# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF1302 PF06980.6 OAI95150.1 - 3.6e-64 217.3 0.9 4e-64 217.1 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1302) Proteasome PF00227.21 OAI95153.1 - 1.1e-16 60.6 0.0 9.4e-15 54.3 0.0 2.0 1 1 0 1 1 1 1 Proteasome subunit Bac_thur_toxin PF01338.13 OAI95158.1 - 0.26 10.4 0.6 0.35 10.0 0.4 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis toxin PAS PF00989.19 OAI95161.1 - 1.1e-17 63.7 0.1 6e-06 26.0 0.0 3.1 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.1 OAI95161.1 - 5.4e-14 51.4 0.0 1.7e-06 27.6 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.6 OAI95161.1 - 9.1e-12 44.9 0.4 5e-08 32.9 0.0 3.1 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.5 OAI95161.1 - 1e-07 31.9 2.6 0.018 15.0 0.1 3.2 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.1 OAI95161.1 - 3.3e-07 30.6 0.0 0.17 12.2 0.0 3.2 3 0 0 3 3 3 3 PAS domain Autotransporter PF03797.14 OAI95175.1 - 8.7e-31 107.2 3.8 1.2e-30 106.7 2.6 1.2 1 0 0 1 1 1 1 Autotransporter beta-domain Ets PF00178.17 OAI95182.1 - 0.083 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Ets-domain Nitr_red_assoc PF09655.5 OAI95182.1 - 0.087 13.1 0.3 0.14 12.5 0.2 1.2 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) ORMDL PF04061.9 OAI95184.1 - 2e-54 182.8 3.2 2.3e-54 182.6 2.2 1.0 1 0 0 1 1 1 1 ORMDL family MerC PF03203.9 OAI95184.1 - 0.1 12.9 1.1 0.17 12.2 0.5 1.6 1 1 0 1 1 1 0 MerC mercury resistance protein DDE_Tnp_4 PF13359.1 OAI95189.1 - 1.9e-27 95.7 0.0 2.4e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAI95189.1 - 0.0023 17.3 0.0 0.0086 15.4 0.0 1.9 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 OAI95189.1 - 0.0034 16.9 0.1 0.019 14.4 0.1 2.1 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.1 OAI95189.1 - 0.012 15.8 0.1 0.027 14.6 0.1 1.5 1 0 0 1 1 1 0 Transposase DDE domain BCA_ABC_TP_C PF12399.3 OAI95189.1 - 0.016 14.8 0.3 0.13 11.9 0.0 2.3 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter Sulfatase PF00884.18 OAI95194.1 - 2.8e-28 99.0 0.0 3e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 OAI95194.1 - 0.048 12.9 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Prenylcys_lyase PF07156.9 OAI95196.1 - 2.9e-16 59.3 0.0 3.3e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase DUF605 PF04652.11 OAI95202.1 - 3.6 6.8 7.7 3.6 6.8 5.3 1.0 1 0 0 1 1 1 0 Vta1 like TrbH PF07283.6 OAI95206.1 - 0.096 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Conjugal transfer protein TrbH DUF3558 PF12079.3 OAI95216.1 - 0.063 12.9 0.1 0.074 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) ADH_N PF08240.7 OAI95217.1 - 0.0017 18.0 0.2 0.0022 17.7 0.1 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain UBN2_2 PF14227.1 OAI95219.1 - 2.1e-05 24.0 0.1 2.5e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAI95219.1 - 0.022 14.5 0.2 0.028 14.2 0.1 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type VP4_haemagglut PF00426.13 OAI95219.1 - 0.023 12.6 0.0 0.028 12.4 0.0 1.0 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) AMP-binding PF00501.23 OAI95229.1 - 1.2e-24 86.5 0.0 1.3e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Pheromone PF08015.6 OAI95235.1 - 0.44 11.4 6.7 1.9 9.3 0.0 3.7 3 1 0 3 3 3 0 Fungal mating-type pheromone zf-RVT PF13966.1 OAI95237.1 - 0.042 14.1 1.4 0.15 12.3 0.1 2.2 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase GGDEF PF00990.16 OAI95241.1 - 5.3e-27 94.3 0.0 1.1e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 GGDEF domain PAS_3 PF08447.6 OAI95241.1 - 1.5e-20 73.0 0.0 3e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 OAI95241.1 - 3.2e-13 49.9 0.0 8.8e-13 48.5 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 OAI95241.1 - 4.8e-10 39.4 2.5 1.1e-09 38.3 0.5 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 OAI95241.1 - 8.4e-09 35.2 0.1 2.7e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 OAI95241.1 - 7.9e-06 25.5 0.0 2.3e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.1 OAI95241.1 - 0.012 15.5 0.0 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 PAS domain L27_N PF09060.5 OAI95241.1 - 0.082 12.7 0.9 11 5.9 0.0 2.6 2 0 0 2 2 2 0 L27_N Afi1 PF07792.7 OAI95257.1 - 4.1e-44 150.1 0.0 5.5e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.4 OAI95257.1 - 6.4e-06 24.9 0.0 2.5e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 OAI95257.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Phage_integrase PF00589.17 OAI95260.1 - 0.0036 16.9 0.0 0.0051 16.5 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family TAP42 PF04177.7 OAI95262.1 - 0.054 12.4 0.2 0.065 12.1 0.1 1.1 1 0 0 1 1 1 0 TAP42-like family DUF1170 PF06663.8 OAI95265.1 - 0.019 14.9 0.3 0.024 14.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1170) ALIX_LYPXL_bnd PF13949.1 OAI95265.1 - 0.021 13.7 0.3 0.024 13.6 0.2 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV AlkA_N PF06029.6 OAI95265.1 - 0.12 12.4 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 AlkA N-terminal domain SRA1 PF07304.6 OAI95274.1 - 0.00034 20.3 0.0 0.00064 19.4 0.0 1.3 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Apolipoprotein PF01442.13 OAI95279.1 - 0.0032 16.9 1.9 0.0042 16.6 1.4 1.2 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4164 PF13747.1 OAI95279.1 - 0.0081 16.2 4.8 0.045 13.8 3.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4164) ISG65-75 PF11727.3 OAI95279.1 - 0.021 13.9 0.2 0.024 13.7 0.2 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein Dzip-like_N PF13815.1 OAI95279.1 - 0.069 12.9 0.6 0.085 12.6 0.4 1.1 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal COG5 PF10392.4 OAI95279.1 - 0.12 12.3 0.9 0.16 11.9 0.6 1.3 1 1 0 1 1 1 0 Golgi transport complex subunit 5 AATF-Che1 PF13339.1 OAI95279.1 - 0.13 12.4 1.1 0.15 12.1 0.8 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor FlgN PF05130.7 OAI95279.1 - 0.16 12.1 3.7 0.44 10.7 2.5 1.7 1 1 0 1 1 1 0 FlgN protein Lipase_GDSL PF00657.17 OAI95283.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 OAI95283.1 - 0.02 15.0 0.0 0.031 14.4 0.0 1.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Nfu_N PF08712.6 OAI95286.1 - 4.5e-33 112.7 0.0 8.5e-33 111.8 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 OAI95286.1 - 2.6e-14 52.7 0.1 4.1e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Med25_NR-box PF11244.3 OAI95286.1 - 0.063 13.7 15.1 0.12 12.8 10.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing MTP18 PF10558.4 OAI95286.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Pex14_N PF04695.8 OAI95286.1 - 0.58 10.1 9.7 1.3 9.0 5.9 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Shisa PF13908.1 OAI95286.1 - 1.6 8.8 5.4 2.3 8.3 3.7 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator AflR PF08493.5 OAI95286.1 - 9.6 5.1 9.4 15 4.5 6.5 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein DUF3492 PF11997.3 OAI95289.1 - 7.6e-74 248.6 0.0 9.6e-74 248.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) TPR_16 PF13432.1 OAI95289.1 - 0.0008 20.0 6.3 0.009 16.6 0.4 1.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAI95289.1 - 0.0027 17.4 1.2 0.0089 15.8 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAI95289.1 - 0.052 13.2 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 TPR repeat TPR_14 PF13428.1 OAI95289.1 - 0.076 13.6 1.2 0.27 11.9 0.9 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAI95289.1 - 0.13 12.8 2.8 0.27 11.7 0.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Pyridoxal_deC PF00282.14 OAI95294.1 - 4.8e-67 225.9 0.0 1.9e-65 220.7 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 OAI95294.1 - 0.00055 19.1 0.0 0.00074 18.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 OAI95294.1 - 0.032 12.9 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Glyoxalase PF00903.20 OAI95294.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily COG5 PF10392.4 OAI95311.1 - 1.1e-10 41.5 1.4 1.8e-10 40.9 1.0 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 RVT_2 PF07727.9 OAI95320.1 - 1.8e-53 181.0 0.0 2.4e-53 180.6 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBN2 PF14223.1 OAI95323.1 - 8.8e-11 41.6 0.0 1.3e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAI95323.1 - 6.3e-10 38.6 0.0 1.1e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 OAI95323.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) DUF4642 PF15484.1 OAI95328.1 - 0.041 13.8 0.6 0.063 13.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) BUD22 PF09073.5 OAI95328.1 - 0.048 12.7 4.4 0.049 12.7 3.1 1.1 1 0 0 1 1 1 0 BUD22 Phostensin_N PF13916.1 OAI95330.1 - 0.057 13.4 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal HEAT_PBS PF03130.11 OAI95334.1 - 0.15 12.6 0.9 15 6.4 0.0 2.2 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Phage_integrase PF00589.17 OAI95338.1 - 4.1e-05 23.3 0.0 4.9e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family DUF4431 PF14485.1 OAI95338.1 - 0.017 14.7 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) UPF0183 PF03676.9 OAI95344.1 - 4.8e-12 45.1 0.0 0.0018 16.9 0.0 3.0 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0183) FAD_binding_2 PF00890.19 OAI95346.1 - 2.6e-14 52.9 0.0 2.7e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain RNA_pol_Rpb1_5 PF04998.12 OAI95354.1 - 8.2e-34 117.1 1.0 1.1e-33 116.7 0.7 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RVT_2 PF07727.9 OAI95356.1 - 9.7e-20 70.5 0.0 1.5e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAI95356.1 - 0.033 13.5 0.1 0.056 12.7 0.1 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cache_2 PF08269.6 OAI95358.1 - 1.7e-05 24.7 0.0 0.065 13.2 0.0 2.4 2 0 0 2 2 2 2 Cache domain MMPL PF03176.10 OAI95364.1 - 0.0013 17.5 0.6 0.0013 17.5 0.4 2.6 2 2 0 2 2 2 1 MMPL family Phage_integrase PF00589.17 OAI95366.1 - 2.2e-05 24.1 0.0 4.4e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Phage integrase family Nop14 PF04147.7 OAI95370.1 - 3.4 5.4 7.2 3.8 5.3 5.0 1.0 1 0 0 1 1 1 0 Nop14-like family Atg14 PF10186.4 OAI95372.1 - 0.06 12.2 34.7 0.27 10.1 5.3 3.0 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3882 PF07066.6 OAI95372.1 - 0.1 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Lactococcus phage M3 protein Filament PF00038.16 OAI95372.1 - 0.14 11.5 36.4 0.72 9.2 7.4 4.4 1 1 2 4 4 4 0 Intermediate filament protein WEMBL PF05701.6 OAI95372.1 - 0.23 9.8 39.2 1.5 7.2 27.2 2.3 1 1 0 1 1 1 0 Weak chloroplast movement under blue light IF-2B PF01008.12 OAI95372.1 - 3.5 6.5 9.7 0.98 8.3 3.7 2.0 1 1 1 2 2 2 0 Initiation factor 2 subunit family Retrotrans_gag PF03732.12 OAI95389.1 - 0.006 16.6 0.2 0.0095 15.9 0.1 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein UQ_con PF00179.21 OAI95398.1 - 4.7e-37 126.5 0.0 5.8e-37 126.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HC2 PF07382.6 OAI95399.1 - 2.6e-08 33.9 38.7 8.8e-05 22.4 13.1 2.7 1 1 2 3 3 3 3 Histone H1-like nucleoprotein HC2 ANAPC15 PF15243.1 OAI95400.1 - 3 7.9 11.9 2.2 8.3 1.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Fasciclin PF02469.17 OAI95404.1 - 2.9e-06 27.2 0.0 1.2e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 Fasciclin domain Glyco_hydro_45 PF02015.11 OAI95408.1 - 1.9e-23 83.5 0.3 2.3e-23 83.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 TetR_N PF00440.18 OAI95415.1 - 3.8e-10 39.2 0.1 7.7e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TMCO5 PF14992.1 OAI95418.1 - 0.029 13.5 2.0 0.061 12.4 1.4 1.6 1 0 0 1 1 1 0 TMCO5 family YgaB PF14182.1 OAI95418.1 - 2.7 8.2 6.8 2.5 8.3 2.2 2.4 2 0 0 2 2 2 0 YgaB-like protein SDA1 PF05285.7 OAI95419.1 - 0.24 10.6 6.3 0.31 10.2 4.4 1.2 1 0 0 1 1 1 0 SDA1 Response_reg PF00072.19 OAI95426.1 - 4.1e-07 29.9 0.0 4.7e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain HD_5 PF13487.1 OAI95427.1 - 5.2e-20 71.1 0.1 9.8e-20 70.3 0.1 1.5 1 0 0 1 1 1 1 HD domain HD PF01966.17 OAI95427.1 - 7.3e-06 26.0 0.1 1.5e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 HD domain Methyltransf_28 PF02636.12 OAI95440.1 - 0.056 12.8 0.2 1.7 7.9 0.2 2.1 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase HisKA_3 PF07730.8 OAI95444.1 - 1.7e-12 47.4 7.6 1.7e-12 47.4 5.3 2.5 3 0 0 3 3 3 1 Histidine kinase HATPase_c PF02518.21 OAI95444.1 - 3.7e-12 45.9 0.0 5.6e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 OAI95444.1 - 2.6e-06 27.2 0.0 5.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF2867 PF11066.3 OAI95444.1 - 0.019 14.6 0.5 0.035 13.8 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2867) HATPase_c_3 PF13589.1 OAI95444.1 - 0.033 13.8 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ACC_epsilon PF13822.1 OAI95444.1 - 0.078 13.3 1.4 0.24 11.8 1.0 1.8 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Response_reg PF00072.19 OAI95445.1 - 2.9e-25 88.4 0.0 4.4e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.23 OAI95445.1 - 4e-25 87.5 0.2 9.8e-25 86.2 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Synapsin_N PF10581.4 OAI95445.1 - 0.016 15.0 0.4 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 Synapsin N-terminal Ribosomal_S21 PF01165.15 OAI95445.1 - 0.15 11.5 0.2 22 4.5 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S21 DUF566 PF04484.7 OAI95448.1 - 0.055 12.9 6.1 0.06 12.8 4.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) Presenilin PF01080.12 OAI95448.1 - 0.27 10.0 1.4 0.32 9.7 1.0 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.8 OAI95448.1 - 0.4 10.5 6.5 0.44 10.3 4.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-CCHC PF00098.18 OAI95454.1 - 0.002 17.9 5.4 0.0039 17.0 3.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAI95454.1 - 0.0077 15.9 0.6 0.018 14.7 0.4 1.7 1 0 0 1 1 1 1 Zinc knuckle DUF4319 PF14203.1 OAI95454.1 - 0.02 14.4 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) TPR_12 PF13424.1 OAI95466.1 - 1.1e-05 25.2 15.9 0.14 12.1 0.2 4.7 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_4 PF07721.9 OAI95466.1 - 0.6 10.6 7.1 44 4.9 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat MutS_III PF05192.13 OAI95474.1 - 3.2e-07 30.3 0.1 4e-07 30.0 0.1 1.1 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 OAI95474.1 - 3.3e-06 27.1 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 MutS family domain IV Orthopox_F6 PF06601.7 OAI95474.1 - 0.051 13.4 0.1 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 Orthopoxvirus F6 protein WXG100 PF06013.7 OAI95474.1 - 0.11 12.4 0.0 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG GILT PF03227.11 OAI95484.1 - 2.8e-08 33.6 0.1 5.5e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) polyprenyl_synt PF00348.12 OAI95489.1 - 2.5e-57 193.7 0.0 3.3e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HTH_1 PF00126.22 OAI95491.1 - 1.4e-16 59.9 0.2 2.9e-16 58.9 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.15 OAI95491.1 - 1.9e-07 30.3 0.1 4.9e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 LysR substrate binding domain HTH_30 PF13556.1 OAI95491.1 - 0.1 12.1 0.0 0.39 10.3 0.0 1.9 1 1 1 2 2 2 0 PucR C-terminal helix-turn-helix domain SHOCT PF09851.4 OAI95491.1 - 7.9 6.1 9.3 19 4.8 0.1 4.0 4 0 0 4 4 4 0 Short C-terminal domain XdhC_CoxI PF02625.11 OAI95492.1 - 2.1e-23 81.7 1.5 4.9e-21 74.1 0.1 2.2 2 0 0 2 2 2 2 XdhC and CoxI family CRISPR_assoc PF08798.6 OAI95499.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 CRISPR associated protein MFS_1 PF07690.11 OAI95504.1 - 2.6e-22 79.0 20.5 3.1e-22 78.7 14.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAI95504.1 - 3e-07 29.3 10.9 4e-07 28.9 7.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 OAI95504.1 - 0.04 12.0 0.8 0.053 11.6 0.4 1.3 1 1 0 1 1 1 0 Transmembrane secretion effector KAAG1 PF15354.1 OAI95505.1 - 1.3 9.4 7.8 2.1 8.7 0.4 2.7 1 1 1 2 2 2 0 Kidney-associated antigen 1 DNA_ligase_OB_2 PF14743.1 OAI95506.1 - 0.00015 21.4 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 DNA ligase OB-like domain Peptidase_S8 PF00082.17 OAI95508.1 - 1e-28 100.3 0.0 2.1e-28 99.2 0.0 1.5 1 1 0 1 1 1 1 Subtilase family PA PF02225.17 OAI95508.1 - 1.1e-09 37.8 0.5 4.4e-09 35.9 0.0 2.2 2 0 0 2 2 2 1 PA domain Aminotran_4 PF01063.14 OAI95517.1 - 2.1e-19 69.8 0.0 2.7e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Acetyltransf_6 PF13480.1 OAI95517.1 - 0.03 14.2 0.0 1.5 8.7 0.0 2.4 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain ABC_tran PF00005.22 OAI95524.1 - 6.4e-08 32.9 0.1 3.2e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC_trans_N PF14510.1 OAI95524.1 - 9.7e-08 31.9 0.1 1.5e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal FtsK_SpoIIIE PF01580.13 OAI95524.1 - 0.06 12.8 0.2 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 OAI95524.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 OAI95524.1 - 0.14 12.1 0.0 2.6 8.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain MutS_V PF00488.16 OAI95527.1 - 0.026 13.9 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 MutS domain V MRP-63 PF14978.1 OAI95527.1 - 0.079 13.4 0.1 0.18 12.2 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 ATP-grasp_4 PF13535.1 OAI95533.1 - 1.4e-19 70.5 0.3 2e-17 63.4 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAI95533.1 - 2.1e-07 30.0 0.0 0.011 14.5 0.0 2.3 1 1 1 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 OAI95533.1 - 0.0006 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Phage_integrase PF00589.17 OAI95535.1 - 0.042 13.5 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family WD40 PF00400.27 OAI95544.1 - 5.2e-28 95.8 2.8 2.6e-09 36.6 0.0 4.2 3 1 1 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 OAI95544.1 - 0.01 13.9 0.1 0.38 8.8 0.0 2.4 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Phlebovirus_G2 PF07245.6 OAI95544.1 - 0.03 12.5 0.0 0.041 12.1 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 BBS2_Mid PF14783.1 OAI95544.1 - 0.093 12.5 0.0 0.77 9.5 0.0 2.3 1 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF1911 PF08929.5 OAI95544.1 - 0.098 13.3 0.4 0.6 10.8 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1911) RVT_2 PF07727.9 OAI95548.1 - 1.8e-71 240.0 0.0 2.2e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GntR PF00392.16 OAI95548.1 - 0.025 14.0 0.1 1.4 8.4 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family GP41 PF00517.12 OAI95563.1 - 0.044 13.3 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Retroviral envelope protein Herpes_US9 PF06072.6 OAI95563.1 - 0.073 12.9 0.5 0.12 12.2 0.4 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Glyco_hydro_30 PF02055.11 OAI95563.1 - 0.095 10.8 0.1 0.1 10.7 0.1 1.1 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 DNA_pol_viral_N PF00242.12 OAI95571.1 - 0.095 11.7 7.3 0.12 11.3 5.1 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 OAI95571.1 - 1.3 7.1 10.2 2 6.6 7.0 1.3 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 OAI95571.1 - 1.5 8.2 31.2 3.2 7.1 21.6 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF572 PF04502.8 OAI95571.1 - 5.8 6.0 11.9 9 5.4 8.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) FHA PF00498.21 OAI95572.1 - 0.00043 20.3 0.0 0.0007 19.6 0.0 1.3 1 0 0 1 1 1 1 FHA domain rRNA_processing PF08524.6 OAI95578.1 - 9.9e-06 25.4 0.1 9.9e-06 25.4 0.1 3.4 3 1 1 4 4 4 2 rRNA processing Retrotrans_gag PF03732.12 OAI95579.1 - 8e-15 54.6 0.6 1.2e-14 54.1 0.4 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAI95579.1 - 0.00011 21.9 1.5 0.00019 21.1 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 OAI95579.1 - 0.18 11.5 3.4 0.34 10.6 2.4 1.4 1 0 0 1 1 1 0 Zinc knuckle An_peroxidase PF03098.10 OAI95582.1 - 0.00018 20.0 0.0 0.00024 19.6 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase VirD1 PF07328.6 OAI95585.1 - 0.063 13.0 0.0 0.077 12.8 0.0 1.1 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 RVT_2 PF07727.9 OAI95586.1 - 5.9e-62 208.8 0.0 7.5e-62 208.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI95588.1 - 4.9e-16 58.9 0.0 7.5e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 OAI95588.1 - 0.00025 20.6 0.1 0.00049 19.7 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Septin PF00735.13 OAI95592.1 - 2e-08 33.5 0.0 2.6e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Septin Snf7 PF03357.16 OAI95597.1 - 1.9e-17 63.1 7.6 2.2e-17 62.9 5.3 1.0 1 0 0 1 1 1 1 Snf7 SYCE1 PF15233.1 OAI95597.1 - 0.0031 17.4 3.1 0.0047 16.8 2.2 1.4 1 1 0 1 1 1 1 Synaptonemal complex central element protein 1 IMP_cyclohyd PF07826.6 OAI95597.1 - 0.032 13.5 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein Ist1 PF03398.9 OAI95597.1 - 0.069 12.5 2.0 0.094 12.1 1.4 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway YlqD PF11068.3 OAI95597.1 - 0.13 12.3 3.3 0.14 12.1 0.7 1.9 1 1 0 2 2 2 0 YlqD protein DUF2155 PF09923.4 OAI95599.1 - 0.03 14.4 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2155) Mito_fiss_reg PF05308.6 OAI95604.1 - 1.8 7.8 5.7 1.9 7.7 0.4 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Macoilin PF09726.4 OAI95604.1 - 2.8 6.1 5.3 6.1 5.0 0.8 2.0 2 0 0 2 2 2 0 Transmembrane protein CENP-B_dimeris PF09026.5 OAI95604.1 - 8.6 6.6 16.9 0.83 9.9 4.3 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain rve PF00665.21 OAI95608.1 - 2.2e-21 76.1 0.0 3.5e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAI95608.1 - 0.00033 20.1 0.0 0.00065 19.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Pheromone PF08015.6 OAI95618.1 - 6.2 7.7 8.8 1.4 9.7 1.2 3.1 3 0 0 3 3 3 0 Fungal mating-type pheromone Collagen_bind_2 PF12904.2 OAI95625.1 - 0.12 12.1 0.3 0.31 10.8 0.2 1.7 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase DUF4102 PF13356.1 OAI95625.1 - 0.23 11.3 1.6 0.35 10.7 0.4 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4102) CAP160 PF07918.6 OAI95625.1 - 1.4 8.6 3.7 0.33 10.6 0.4 1.5 2 0 0 2 2 2 0 CAP160 repeat DDE_Tnp_4 PF13359.1 OAI95628.1 - 2.9e-21 75.7 0.0 3.8e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 OAI95628.1 - 0.00044 19.8 0.4 0.026 14.0 0.0 2.6 3 1 0 3 3 3 2 Transposase DDE domain Asn_synthase PF00733.16 OAI95641.1 - 4.8e-13 49.1 0.1 1.7e-12 47.3 0.0 1.7 1 1 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 OAI95641.1 - 0.005 15.7 0.0 0.0065 15.4 0.0 1.1 1 0 0 1 1 1 1 NAD synthase Ribosomal_60s PF00428.14 OAI95641.1 - 0.018 15.4 0.6 0.027 14.8 0.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein AalphaY_MDB PF04611.7 OAI95641.1 - 0.075 12.9 0.1 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region QueC PF06508.8 OAI95641.1 - 0.15 11.2 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Retrotrans_gag PF03732.12 OAI95644.1 - 0.037 14.0 0.0 0.096 12.7 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein ResIII PF04851.10 OAI95648.1 - 1.1e-13 51.4 0.0 2e-13 50.5 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAI95648.1 - 0.0038 16.7 0.0 0.064 12.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase FAP PF07174.6 OAI95651.1 - 1.4 8.1 14.8 1.6 7.9 10.3 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PAT1 PF09770.4 OAI95651.1 - 3.3 5.8 8.1 3 5.9 5.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ATP-synt_G PF04718.10 OAI95660.1 - 2.3e-16 60.3 1.5 5.3e-16 59.1 0.1 2.1 1 1 1 2 2 2 1 Mitochondrial ATP synthase g subunit ApoC-I PF04691.7 OAI95660.1 - 0.02 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) SR-25 PF10500.4 OAI95660.1 - 0.26 10.7 7.8 0.36 10.2 5.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein KdpC PF02669.10 OAI95660.1 - 5.2 6.7 8.8 7.4 6.2 6.1 1.2 1 0 0 1 1 1 0 K+-transporting ATPase, c chain DUF2514 PF10721.4 OAI95662.1 - 0.11 12.2 2.1 0.19 11.4 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) RNA_pol_3_Rpc31 PF11705.3 OAI95667.1 - 3.4e-25 89.3 25.7 6.3e-25 88.4 17.8 1.5 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Cation_ATPase_N PF00690.21 OAI95673.1 - 6.9e-05 22.2 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Frag1 PF10277.4 OAI95674.1 - 1.7e-15 57.0 5.1 2.2e-15 56.7 3.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2079 PF09852.4 OAI95674.1 - 0.053 12.2 1.5 0.1 11.2 1.0 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2079) Ail_Lom PF06316.6 OAI95677.1 - 0.35 10.3 0.1 0.35 10.3 0.0 1.9 3 0 0 3 3 3 0 Enterobacterial Ail/Lom protein GRP PF07172.6 OAI95677.1 - 6.8 7.2 24.8 0.45 11.0 0.1 3.3 2 1 0 3 3 3 0 Glycine rich protein family KOW PF00467.24 OAI95683.1 - 0.00027 20.5 5.1 0.28 10.9 0.1 3.5 3 0 0 3 3 3 2 KOW motif DUF3006 PF11213.3 OAI95683.1 - 0.015 15.0 0.2 0.12 12.0 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3006) Dimer_Tnp_hAT PF05699.9 OAI95685.1 - 2.2e-08 33.6 0.0 3.6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAI95685.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) DUF1034 PF06280.7 OAI95698.1 - 1.8e-13 50.8 0.1 3.1e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) NAD_binding_4 PF07993.7 OAI95706.1 - 8.3e-09 34.7 0.0 1.2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 OAI95706.1 - 1.2e-05 24.9 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Retrotrans_gag PF03732.12 OAI95725.1 - 0.037 14.0 0.0 0.093 12.8 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Mt_ATP-synt_B PF05405.9 OAI95734.1 - 0.0083 15.5 0.6 0.0095 15.4 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) YlqD PF11068.3 OAI95734.1 - 0.018 15.0 2.3 0.021 14.8 1.6 1.1 1 0 0 1 1 1 0 YlqD protein LEA_4 PF02987.11 OAI95734.1 - 0.054 13.3 7.0 0.091 12.6 4.8 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein Spc24 PF08286.6 OAI95734.1 - 0.14 11.8 1.4 0.17 11.5 1.0 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Atg14 PF10186.4 OAI95734.1 - 0.68 8.8 2.6 0.76 8.6 1.8 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FadA PF09403.5 OAI95734.1 - 5.5 7.0 7.0 6.6 6.7 4.9 1.1 1 0 0 1 1 1 0 Adhesion protein FadA HsbA PF12296.3 OAI95736.1 - 1.4e-08 34.6 7.9 1.8e-08 34.3 5.5 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Pox_A6 PF04924.7 OAI95736.1 - 0.17 10.6 1.3 0.19 10.5 0.9 1.0 1 0 0 1 1 1 0 Poxvirus A6 protein FUN14 PF04930.10 OAI95736.1 - 0.2 11.9 1.0 0.3 11.3 0.7 1.4 1 1 0 1 1 1 0 FUN14 family ApbA PF02558.11 OAI95741.1 - 1.4e-08 34.3 0.0 2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA RdRP_2 PF00978.16 OAI95743.1 - 1.1e-13 50.7 0.0 1.4e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Serpin PF00079.15 OAI95743.1 - 0.014 14.5 0.1 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) PAS_9 PF13426.1 OAI95746.1 - 5.9e-34 116.5 0.0 1.9e-25 89.2 0.0 2.8 2 1 0 2 2 2 2 PAS domain PAS_8 PF13188.1 OAI95746.1 - 2.1e-16 59.0 0.2 1.2e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 OAI95746.1 - 3.7e-15 55.6 0.2 3.8e-09 36.3 0.0 2.8 1 1 2 3 3 3 2 PAS fold PAS_4 PF08448.5 OAI95746.1 - 7.2e-14 51.7 0.2 1.2e-08 34.9 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.6 OAI95746.1 - 1.1e-12 47.8 0.1 2.9e-08 33.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold Response_reg PF00072.19 OAI95746.1 - 0.00071 19.5 0.0 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain GGDEF PF00990.16 OAI95746.1 - 0.0067 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 GGDEF domain MEKHLA PF08670.6 OAI95746.1 - 0.042 13.3 0.0 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 MEKHLA domain Phage_integrase PF00589.17 OAI95748.1 - 0.00046 19.9 0.0 0.0005 19.7 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family CHRD PF07452.7 OAI95750.1 - 0.00012 22.7 0.0 0.00031 21.3 0.0 1.7 1 1 0 1 1 1 1 CHRD domain RVT_2 PF07727.9 OAI95755.1 - 4.9e-34 117.3 0.0 5.3e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RuvC PF02075.12 OAI95756.1 - 0.048 13.4 0.1 0.4 10.5 0.1 2.1 2 0 0 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC RVT_3 PF13456.1 OAI95756.1 - 0.073 12.8 0.1 0.26 11.1 0.0 2.1 2 1 0 2 2 2 0 Reverse transcriptase-like Cellulase PF00150.13 OAI95758.1 - 0.11 11.6 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.11 OAI95760.1 - 0.0025 16.6 2.5 0.0025 16.6 1.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily CAAD PF14159.1 OAI95760.1 - 0.016 14.8 0.8 0.53 9.9 0.0 2.8 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase HTH_OrfB_IS605 PF12323.3 OAI95781.1 - 4.2e-11 41.9 1.5 8e-11 41.0 1.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Thi4 PF01946.12 OAI95783.1 - 0.00069 18.7 0.0 0.0009 18.4 0.0 1.1 1 0 0 1 1 1 1 Thi4 family RNase_H PF00075.19 OAI95787.1 - 0.0024 18.2 0.0 0.0045 17.3 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAI95787.1 - 0.042 13.6 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like Ank PF00023.25 OAI95795.1 - 0.0069 16.1 0.0 0.039 13.7 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 OAI95795.1 - 0.02 15.0 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.2 OAI95795.1 - 0.021 15.1 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAI95795.1 - 0.094 13.2 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Sec66 PF09802.4 OAI95800.1 - 2.6e-49 167.1 0.1 4e-49 166.5 0.1 1.3 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 EBV-NA3 PF05009.7 OAI95800.1 - 0.067 12.4 5.9 0.62 9.2 0.0 2.3 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) PPP4R2 PF09184.6 OAI95800.1 - 1.6 8.2 11.8 2.4 7.6 8.2 1.3 1 0 0 1 1 1 0 PPP4R2 FLO_LFY PF01698.11 OAI95800.1 - 2 7.1 12.1 1.3 7.8 6.6 1.7 1 1 1 2 2 2 0 Floricaula / Leafy protein RR_TM4-6 PF06459.7 OAI95800.1 - 2.2 8.1 12.6 3.6 7.3 8.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-C3HC4_3 PF13920.1 OAI95815.1 - 0.022 14.4 4.7 0.042 13.5 3.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAI95815.1 - 0.29 10.8 7.9 0.52 10.0 5.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pro_racemase PF05544.6 OAI95820.1 - 0.068 11.9 0.1 0.083 11.7 0.1 1.1 1 0 0 1 1 1 0 Proline racemase Trypan_PARP PF05887.6 OAI95824.1 - 5.3 6.8 14.3 0.31 10.8 1.7 2.7 2 1 1 3 3 3 0 Procyclic acidic repetitive protein (PARP) zf-CCHC PF00098.18 OAI95827.1 - 0.0002 21.1 12.1 0.0023 17.7 0.8 3.2 2 1 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 OAI95827.1 - 2.8 7.5 9.0 3.1 7.3 1.1 2.8 1 1 1 2 2 2 0 Zinc knuckle DSHCT PF08148.7 OAI95829.1 - 7.5e-28 96.9 0.2 1.6e-27 95.8 0.1 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain BAR PF03114.13 OAI95840.1 - 2.5e-40 138.4 0.7 3.4e-40 137.9 0.5 1.1 1 0 0 1 1 1 1 BAR domain FAM92 PF06730.6 OAI95840.1 - 0.0022 17.3 0.8 0.0033 16.7 0.6 1.2 1 0 0 1 1 1 1 FAM92 protein BLYB PF05289.6 OAI95840.1 - 0.026 14.3 0.1 0.07 12.9 0.0 1.7 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein zf-CCHC PF00098.18 OAI95844.1 - 0.25 11.3 5.7 0.25 11.3 2.8 1.9 2 0 0 2 2 2 0 Zinc knuckle DUF2235 PF09994.4 OAI95848.1 - 0.00031 20.2 0.0 0.00038 19.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) RVT_2 PF07727.9 OAI95851.1 - 2.7e-46 157.5 0.0 3.5e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_bind PF08675.6 OAI95851.1 - 0.13 12.2 0.0 0.56 10.2 0.0 2.0 1 0 0 1 1 1 0 RNA binding domain DUF1820 PF08850.6 OAI95851.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1820) Dimer_Tnp_hAT PF05699.9 OAI95858.1 - 4.5e-10 39.0 0.0 6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3489 PF11994.3 OAI95858.1 - 0.038 13.9 0.2 0.086 12.7 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3489) HTH_Tnp_Tc3_2 PF01498.13 OAI95863.1 - 1.8e-11 43.8 0.0 2.7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Transposase DUF2789 PF10982.3 OAI95863.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) AAA_28 PF13521.1 OAI95863.1 - 0.074 13.0 0.0 0.087 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain Exo_endo_phos PF03372.18 OAI95864.1 - 1e-09 38.6 0.1 1.5e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family p450 PF00067.17 OAI95867.1 - 1.6e-35 122.5 0.0 2.1e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ldh_1_C PF02866.13 OAI95874.1 - 4.8e-20 71.9 0.0 6.2e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Retrotrans_gag PF03732.12 OAI95876.1 - 0.14 12.2 0.3 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein HSP70 PF00012.15 OAI95879.1 - 9.6e-14 50.2 0.2 1.1e-13 49.9 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein FtsA PF14450.1 OAI95879.1 - 0.0037 17.0 0.1 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 Cell division protein FtsA DbpA PF03880.10 OAI95879.1 - 0.06 13.0 0.0 0.074 12.7 0.0 1.1 1 0 0 1 1 1 0 DbpA RNA binding domain Hydantoinase_A PF01968.13 OAI95879.1 - 0.077 12.0 0.7 0.087 11.9 0.5 1.0 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase RRM_1 PF00076.17 OAI95880.1 - 2.8e-06 26.8 0.0 3.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAI95880.1 - 1.1e-05 25.2 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAI95880.1 - 1.7e-05 24.6 0.0 2.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Phage_integrase PF00589.17 OAI95883.1 - 0.03 14.0 0.1 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family CbiA PF01656.18 OAI95885.1 - 4.5e-25 88.1 0.0 5.2e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 OAI95885.1 - 2e-10 40.8 0.2 7.1e-10 39.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 OAI95885.1 - 7e-09 35.1 0.3 1.2e-07 31.0 0.2 2.0 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 OAI95885.1 - 2.6e-07 29.9 0.0 3.5e-07 29.5 0.0 1.4 2 0 0 2 2 2 1 Anion-transporting ATPase YhjQ PF06564.7 OAI95885.1 - 7.9e-06 25.4 0.2 1e-05 25.0 0.1 1.2 1 1 0 1 1 1 1 YhjQ protein VirC1 PF07015.6 OAI95885.1 - 1.2e-05 24.5 0.0 0.00017 20.7 0.0 2.0 2 0 0 2 2 2 1 VirC1 protein SRP54 PF00448.17 OAI95885.1 - 0.00082 18.8 0.1 0.047 13.1 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 OAI95885.1 - 0.00087 18.7 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 OAI95885.1 - 0.006 15.8 0.0 0.0069 15.6 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MobB PF03205.9 OAI95885.1 - 0.0069 16.1 0.1 0.027 14.1 0.1 1.9 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 OAI95885.1 - 0.032 14.3 0.0 0.037 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAI95885.1 - 0.1 12.3 1.0 0.21 11.3 0.7 1.7 1 1 0 1 1 1 0 Part of AAA domain Phage_AlpA PF05930.7 OAI95886.1 - 1.3e-19 69.6 0.1 1.7e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Prophage CP4-57 regulatory protein (AlpA) LysR_substrate PF03466.15 OAI95886.1 - 1.9e-05 23.8 0.0 2.4e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_17 PF12728.2 OAI95886.1 - 0.0056 16.8 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Zip PF02535.17 OAI95893.1 - 2e-05 23.8 0.9 2.5e-05 23.4 0.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter BAF1_ABF1 PF04684.8 OAI95893.1 - 7e-05 21.8 18.5 9.2e-05 21.4 12.8 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Methyltransf_16 PF10294.4 OAI95893.1 - 0.0056 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase DUF2946 PF11162.3 OAI95893.1 - 0.02 15.0 3.2 0.02 15.0 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Pex14_N PF04695.8 OAI95893.1 - 0.056 13.4 4.0 0.087 12.8 0.9 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4366 PF14283.1 OAI95893.1 - 0.092 12.1 0.2 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Neur_chan_memb PF02932.11 OAI95893.1 - 0.12 12.2 0.1 0.14 12.0 0.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PDGF_N PF04692.8 OAI95893.1 - 0.21 12.0 5.1 0.38 11.2 3.5 1.3 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region NUT_N PF12881.2 OAI95893.1 - 0.27 10.3 4.9 0.19 10.8 1.5 1.8 2 0 0 2 2 2 0 NUT protein N terminus Mucin PF01456.12 OAI95893.1 - 3.1 7.5 5.9 0.79 9.5 0.4 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein zf-MYND PF01753.13 OAI95907.1 - 3.6e-05 23.5 20.4 7.3e-05 22.5 14.2 1.6 1 1 0 1 1 1 1 MYND finger Myb_DNA-bind_3 PF12776.2 OAI95914.1 - 0.0015 19.0 1.0 0.0022 18.5 0.3 1.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain PBP1_TM PF14812.1 OAI95914.1 - 0.014 15.7 1.8 0.014 15.7 1.3 1.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0167 PF03691.9 OAI95914.1 - 0.14 11.5 0.8 0.27 10.6 0.5 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0167) Sigma70_ner PF04546.8 OAI95914.1 - 0.17 11.4 2.7 0.19 11.3 1.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.5 OAI95914.1 - 0.49 9.4 7.1 0.57 9.1 4.9 1.0 1 0 0 1 1 1 0 BUD22 Nucleoplasmin PF03066.10 OAI95914.1 - 1.4 8.4 5.1 1.7 8.1 3.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin Asp_protease_2 PF13650.1 OAI95918.1 - 0.087 13.3 0.1 1.7 9.2 0.0 2.7 2 1 0 2 2 2 0 Aspartyl protease Serinc PF03348.10 OAI95925.1 - 4.3e-25 88.3 0.0 5.1e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) BTP PF05232.7 OAI95932.1 - 0.017 14.8 1.0 0.024 14.3 0.7 1.3 1 0 0 1 1 1 0 Bacterial Transmembrane Pair family DUF3180 PF11377.3 OAI95932.1 - 0.1 12.4 2.8 0.16 11.8 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3180) CRAL_TRIO PF00650.15 OAI95933.1 - 2.8e-29 101.6 0.0 3.8e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAI95933.1 - 3.9e-09 36.4 0.6 1.2e-08 34.9 0.4 2.0 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain UPF0181 PF03701.9 OAI95940.1 - 0.092 12.0 0.8 0.55 9.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) ATE_N PF04376.8 OAI95941.1 - 1.4e-23 82.5 0.2 2.3e-23 81.8 0.2 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus ATE_C PF04377.10 OAI95941.1 - 8.1e-06 25.9 0.1 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus PQ-loop PF04193.9 OAI95943.1 - 4e-11 42.2 0.2 5.9e-11 41.7 0.1 1.3 1 0 0 1 1 1 1 PQ loop repeat DUF4537 PF15057.1 OAI95946.1 - 0.0072 16.1 0.1 0.041 13.6 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) GOLD_2 PF13897.1 OAI95946.1 - 0.04 14.1 0.0 0.049 13.8 0.0 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Imm32 PF15579.1 OAI95949.1 - 6.1e-06 25.7 0.0 1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Immunity protein 32 Spt5-NGN PF03439.8 OAI95950.1 - 5.5e-20 70.8 0.0 1.4e-19 69.5 0.0 1.8 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 OAI95950.1 - 9.9e-10 38.9 3.1 9.9e-10 38.9 2.1 3.1 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal ADH_N_assoc PF13823.1 OAI95950.1 - 0.0019 17.7 0.1 0.0059 16.2 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated DUF2457 PF10446.4 OAI95950.1 - 1.3 7.6 24.2 2.6 6.6 16.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 OAI95950.1 - 8.8 4.2 13.6 14 3.6 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Cyt-b5 PF00173.23 OAI95954.1 - 1.5e-21 75.9 0.0 1.8e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Leuk-A4-hydro_C PF09127.6 OAI95957.1 - 1.7e-44 150.9 0.0 2.6e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Gly-zipper_OmpA PF13436.1 OAI95969.1 - 0.00069 19.2 1.1 0.0014 18.2 0.8 1.5 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain DUF1269 PF06897.7 OAI95969.1 - 0.091 12.8 0.1 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) DUF2051 PF09738.4 OAI95974.1 - 0.012 14.9 1.3 0.013 14.8 0.9 1.0 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Herpes_capsid PF06112.6 OAI95974.1 - 1 9.4 11.1 1.1 9.2 7.7 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein UQ_con PF00179.21 OAI95977.1 - 1.6e-41 141.0 0.0 2.1e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 OAI95977.1 - 0.0049 16.7 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 OAI95977.1 - 0.033 13.9 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Nop14 PF04147.7 OAI95999.1 - 2.8 5.7 6.0 3.4 5.4 4.2 1.1 1 0 0 1 1 1 0 Nop14-like family Abhydrolase_3 PF07859.8 OAI96000.1 - 4e-06 26.5 0.0 4.1e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAI96000.1 - 0.011 14.4 0.0 0.012 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Spt20 PF12090.3 OAI96004.1 - 2.7 7.2 7.7 4.8 6.4 1.5 2.2 2 0 0 2 2 2 0 Spt20 family FimP PF09766.4 OAI96004.1 - 3 6.8 12.8 3.7 6.5 0.3 2.3 2 0 0 2 2 2 0 Fms-interacting protein OmpH PF03938.9 OAI96004.1 - 5.5 6.9 12.7 3.5 7.5 0.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Transthyretin PF00576.16 OAI96006.1 - 4.7e-31 106.9 0.0 4.8e-30 103.7 0.0 1.9 1 1 0 1 1 1 1 HIUase/Transthyretin family Clathrin_H_link PF13838.1 OAI96011.1 - 1.9e-29 101.3 0.0 2.9e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Clathrin-H-link Hid1 PF12722.2 OAI96018.1 - 1.6e-28 98.9 0.2 2e-28 98.6 0.1 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 OAI96018.1 - 1.7e-09 36.3 0.4 9.9e-09 33.8 0.0 1.8 1 1 1 2 2 2 1 Dyggve-Melchior-Clausen syndrome protein DUF605 PF04652.11 OAI96018.1 - 0.02 14.2 9.5 0.024 14.0 6.6 1.1 1 0 0 1 1 1 0 Vta1 like Glyoxalase_2 PF12681.2 OAI96025.1 - 3.9e-08 33.8 0.0 1.4e-07 32.0 0.0 1.9 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.20 OAI96025.1 - 0.017 15.0 0.0 0.22 11.5 0.0 2.5 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HeH PF12949.2 OAI96036.1 - 0.011 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 HeH/LEM domain DUF3136 PF11334.3 OAI96036.1 - 0.077 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) ThiW PF09512.5 OAI96036.1 - 0.092 12.5 0.8 0.15 11.9 0.1 1.6 2 0 0 2 2 2 0 Thiamine-precursor transporter protein (ThiW) Glyco_hydro_45 PF02015.11 OAI96038.1 - 1.1e-16 61.5 2.9 1.4e-16 61.1 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 DnaJ PF00226.26 OAI96041.1 - 0.00046 19.8 0.0 0.0015 18.2 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Sec62 PF03839.11 OAI96041.1 - 0.0068 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 DDHD PF02862.12 OAI96041.1 - 0.99 9.1 5.4 1.3 8.7 3.8 1.1 1 0 0 1 1 1 0 DDHD domain DUF1703 PF08011.6 OAI96041.1 - 1.7 8.3 6.6 10 5.9 5.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1703) CDC45 PF02724.9 OAI96041.1 - 7.4 4.4 9.3 9 4.1 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Phage_integrase PF00589.17 OAI96045.1 - 3.3e-05 23.6 0.0 5.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Acetate_kinase PF00871.12 OAI96046.1 - 2.3e-20 72.5 0.0 2.5e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family ImcF-related_N PF14331.1 OAI96051.1 - 1e-31 109.8 0.5 8.1e-31 106.8 0.4 1.9 1 1 0 1 1 1 1 ImcF-related N-terminal domain CDC45 PF02724.9 OAI96055.1 - 0.013 13.6 1.3 0.019 13.0 0.7 1.5 1 1 1 2 2 2 0 CDC45-like protein UPF0104 PF03706.8 OAI96055.1 - 0.02 14.1 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) VID27 PF08553.5 OAI96055.1 - 1.5 6.9 5.3 2 6.5 3.7 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Myc_N PF01056.13 OAI96055.1 - 1.9 7.5 11.2 1.5 7.9 1.2 2.1 2 0 0 2 2 2 0 Myc amino-terminal region Prothymosin PF03247.9 OAI96055.1 - 4 7.6 27.0 0.36 11.0 13.1 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family Nop14 PF04147.7 OAI96055.1 - 9.9 3.9 16.6 16 3.2 11.5 1.3 1 0 0 1 1 1 0 Nop14-like family Collagen PF01391.13 OAI96061.1 - 4.1e-26 90.2 133.4 5.2e-11 41.9 24.8 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) HeH PF12949.2 OAI96073.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 HeH/LEM domain DUF3136 PF11334.3 OAI96073.1 - 0.072 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) RVT_3 PF13456.1 OAI96079.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like DUF726 PF05277.7 OAI96081.1 - 9.6 4.9 6.6 17 4.1 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Med15 PF09606.5 OAI96094.1 - 0.032 12.4 16.9 0.04 12.1 11.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 OAI96094.1 - 0.59 8.3 14.1 0.91 7.6 9.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 OAI96094.1 - 3.2 5.3 14.2 4.4 4.8 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MCM PF00493.18 OAI96095.1 - 2.7e-38 131.6 0.0 3.1e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 OAI96095.1 - 0.064 12.3 0.1 0.18 10.9 0.1 1.7 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF427 PF04248.7 OAI96098.1 - 5e-11 42.1 0.1 1e-10 41.1 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF427) HrpB1_HrpK PF09613.5 OAI96099.1 - 0.44 10.0 2.3 0.3 10.5 0.1 1.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Lamp PF01299.12 OAI96099.1 - 6.9 5.7 6.9 10 5.1 4.8 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Methyltransf_16 PF10294.4 OAI96103.1 - 2.3e-07 30.4 0.0 4e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 OAI96103.1 - 5.6e-06 26.9 0.0 9.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 OAI96103.1 - 0.00024 20.3 0.0 0.00038 19.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 OAI96103.1 - 0.0021 18.0 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAI96103.1 - 0.045 13.4 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 OAI96103.1 - 0.054 13.9 0.0 0.1 13.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 OAI96103.1 - 0.058 12.9 0.0 0.68 9.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Baculo_p48 PF04878.8 OAI96106.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Baculovirus P48 protein Tom37_C PF11801.3 OAI96107.1 - 1.6 8.5 5.3 2.5 7.9 3.7 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Spore_coat_CotO PF14153.1 OAI96107.1 - 4 6.8 8.5 6.1 6.2 5.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Peptidase_M1 PF01433.15 OAI96111.1 - 4.4e-59 200.5 0.0 6e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 OAI96111.1 - 1e-07 32.0 0.1 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily DUF3439 PF11921.3 OAI96111.1 - 0.62 9.8 4.7 1.3 8.7 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) rve PF00665.21 OAI96115.1 - 4.1e-22 78.5 0.1 7.6e-22 77.6 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAI96115.1 - 0.00064 19.1 0.0 0.0016 17.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain PAS_3 PF08447.6 OAI96115.1 - 0.041 13.9 0.8 0.14 12.2 0.5 1.9 1 0 0 1 1 1 0 PAS fold WD40 PF00400.27 OAI96119.1 - 3.3e-17 61.6 4.5 7.7e-07 28.7 0.0 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 OAI96119.1 - 9.9e-07 27.2 2.0 0.0017 16.5 0.1 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Cortex-I_coil PF09304.5 OAI96119.1 - 0.16 11.9 4.1 0.29 11.1 2.9 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil NPIP PF06409.6 OAI96124.1 - 0.065 11.9 1.4 0.12 11.0 1.0 1.5 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) YiiD_Cterm PF09500.5 OAI96124.1 - 0.16 11.5 1.6 0.2 11.1 0.1 1.9 2 0 0 2 2 2 0 Putative thioesterase (yiiD_Cterm) DUF4041 PF13250.1 OAI96124.1 - 0.55 9.8 3.8 20 4.8 0.1 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4041) DUF720 PF05302.6 OAI96124.1 - 0.76 9.5 11.9 0.026 14.3 2.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF720) NPV_P10 PF05531.7 OAI96124.1 - 1.2 9.3 14.0 3 8.1 0.9 4.5 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1342 PF07072.6 OAI96124.1 - 4 7.0 17.3 0.29 10.7 3.0 3.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1342) Filament PF00038.16 OAI96124.1 - 9.9 5.5 37.9 2.7 7.3 4.9 3.8 1 1 3 4 4 4 0 Intermediate filament protein DUF605 PF04652.11 OAI96128.1 - 0.47 9.8 23.6 0.52 9.6 16.3 1.1 1 0 0 1 1 1 0 Vta1 like Gemini_AL2 PF01440.11 OAI96128.1 - 9.6 6.3 10.3 3.7 7.6 4.9 1.9 1 1 1 2 2 2 0 Geminivirus AL2 protein Septin PF00735.13 OAI96133.1 - 1.8e-110 368.4 0.2 2.2e-110 368.0 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 OAI96133.1 - 1.9e-08 34.2 0.0 5.1e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 OAI96133.1 - 6.1e-05 22.2 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 OAI96133.1 - 0.0002 20.5 1.0 0.00037 19.6 0.0 2.0 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.22 OAI96133.1 - 0.00052 19.5 0.6 0.0067 15.8 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 OAI96133.1 - 0.0021 17.5 0.0 0.0056 16.1 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 OAI96133.1 - 0.0028 17.4 3.5 0.56 10.0 0.1 2.7 2 1 1 3 3 3 2 Dynamin family AAA_10 PF12846.2 OAI96133.1 - 0.019 14.4 0.2 0.035 13.5 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 OAI96133.1 - 0.026 14.7 0.0 0.061 13.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 OAI96133.1 - 0.027 13.3 0.0 0.057 12.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 OAI96133.1 - 0.098 12.7 0.0 0.28 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 OAI96133.1 - 0.12 13.1 2.4 14 6.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 OAI96133.1 - 0.13 12.1 0.7 2.9 7.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 OAI96133.1 - 1.1 9.0 3.5 2 8.1 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_23 PF13476.1 OAI96133.1 - 3.4 7.9 6.6 17 5.6 4.5 2.0 1 1 0 1 1 1 0 AAA domain Peptidase_M16 PF00675.15 OAI96140.1 - 7.7e-22 77.6 0.0 9.3e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Transaldolase PF00923.14 OAI96140.1 - 0.011 14.9 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 0 Transaldolase HlyD_3 PF13437.1 OAI96141.1 - 8.3e-14 51.8 0.0 4.5e-13 49.4 0.0 1.9 1 1 0 1 1 1 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 OAI96141.1 - 9.2e-06 25.2 0.3 5.6e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD PF00529.15 OAI96141.1 - 0.062 12.6 0.1 0.12 11.6 0.0 1.5 1 1 0 1 1 1 0 HlyD family secretion protein Biotin_lipoyl PF00364.17 OAI96141.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Biotin-requiring enzyme LRR_6 PF13516.1 OAI96145.1 - 6e-12 44.3 5.8 0.055 13.5 0.0 7.4 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.2 OAI96145.1 - 3.1e-08 33.0 8.2 0.0053 16.3 0.6 6.1 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAI96145.1 - 2.3e-06 27.2 10.0 0.04 13.6 0.4 5.4 4 2 2 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 OAI96145.1 - 1.1e-05 24.7 1.1 7.7 6.9 0.0 6.7 7 2 0 7 7 7 1 Leucine Rich Repeat Plasmodium_Vir PF05795.6 OAI96145.1 - 1.2 8.2 3.4 1.2 8.2 1.2 1.8 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SAPS PF04499.10 OAI96145.1 - 1.4 7.4 4.0 1.8 7.1 2.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein YqfQ PF14181.1 OAI96145.1 - 4.5 7.2 7.7 12 5.9 5.4 1.8 1 0 0 1 1 1 0 YqfQ-like protein Daxx PF03344.10 OAI96145.1 - 6.3 5.1 22.6 8.9 4.6 15.7 1.2 1 0 0 1 1 1 0 Daxx Family Paf1 PF03985.8 OAI96145.1 - 7.5 5.1 17.7 0.9 8.2 9.6 1.4 2 0 0 2 2 2 0 Paf1 LRR_7 PF13504.1 OAI96145.1 - 9.3 6.9 7.5 22 5.8 0.1 5.1 7 0 0 7 7 7 0 Leucine rich repeat DDE_3 PF13358.1 OAI96148.1 - 4.5e-14 52.4 0.0 6.6e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 OAI96148.1 - 8.9e-11 41.7 0.1 1.4e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 Transposase Transthyretin PF00576.16 OAI96150.1 - 7.1e-36 122.5 0.0 8.2e-36 122.2 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family MG1 PF11974.3 OAI96150.1 - 0.00055 20.4 0.0 0.00071 20.0 0.0 1.1 1 0 0 1 1 1 1 Alpha-2-macroglobulin MG1 domain DUF4469 PF14734.1 OAI96150.1 - 0.014 15.2 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold A2M_N PF01835.14 OAI96150.1 - 0.016 15.4 0.1 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 MG2 domain Big_1 PF02369.11 OAI96150.1 - 0.021 14.7 0.1 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) DUF824 PF05688.6 OAI96150.1 - 0.041 13.5 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) CarboxypepD_reg PF13620.1 OAI96150.1 - 0.073 13.1 0.1 0.17 11.9 0.1 1.6 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain CopC PF04234.7 OAI96150.1 - 0.14 12.7 0.0 0.19 12.3 0.0 1.2 1 0 0 1 1 1 0 CopC domain Cna_B PF05738.8 OAI96150.1 - 0.16 11.7 1.0 0.31 10.8 0.7 1.5 1 1 0 1 1 1 0 Cna protein B-type domain Hydrolase_like PF13242.1 OAI96152.1 - 1.2e-09 37.7 0.1 1.4e-09 37.5 0.1 1.0 1 0 0 1 1 1 1 HAD-hyrolase-like CFEM PF05730.6 OAI96153.1 - 8.4e-09 35.1 11.4 1.5e-08 34.3 7.9 1.4 1 0 0 1 1 1 1 CFEM domain PEP-utilizers PF00391.18 OAI96153.1 - 0.37 10.3 3.8 0.96 9.0 0.0 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain HSP70 PF00012.15 OAI96155.1 - 4.8e-07 28.0 0.1 5.9e-07 27.7 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein Nipped-B_C PF12830.2 OAI96158.1 - 4.6e-24 85.0 0.2 5.9e-24 84.7 0.2 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus Cnl2_NKP2 PF09447.5 OAI96158.1 - 0.073 12.7 0.3 0.34 10.6 0.0 2.1 2 1 0 2 2 2 0 Cnl2/NKP2 family protein Asp_protease_2 PF13650.1 OAI96161.1 - 0.002 18.5 0.0 0.0048 17.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 OAI96163.1 - 0.14 12.1 4.1 0.25 11.3 2.8 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 OAI96170.1 - 3.6e-18 65.7 0.0 6.6e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI96170.1 - 0.091 12.8 0.0 0.8 9.8 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain UDPG_MGDP_dh PF00984.14 OAI96173.1 - 5.7e-26 90.5 0.0 1.1e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 OAI96173.1 - 6.4e-23 80.9 0.0 1.5e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh_N PF03721.9 OAI96173.1 - 1.6e-20 73.2 0.0 7.9e-20 71.0 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ANT PF03374.9 OAI96173.1 - 0.034 14.1 0.0 4.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Phage antirepressor protein KilAC domain DUF2624 PF11116.3 OAI96173.1 - 0.059 13.8 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) DUF1912 PF08930.5 OAI96174.1 - 0.032 14.3 0.3 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1912) Carn_acyltransf PF00755.15 OAI96186.1 - 2.3e-48 164.6 0.0 1e-47 162.5 0.0 1.9 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Nop14 PF04147.7 OAI96191.1 - 0.00033 18.7 13.0 0.00035 18.6 9.0 1.1 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 OAI96191.1 - 0.003 16.1 15.4 0.0039 15.7 10.7 1.1 1 0 0 1 1 1 1 Daxx Family SDA1 PF05285.7 OAI96191.1 - 0.018 14.3 13.7 0.024 13.9 9.5 1.2 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.8 OAI96191.1 - 0.019 14.5 11.9 0.035 13.7 8.2 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 OAI96191.1 - 0.024 12.7 8.3 0.029 12.4 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 OAI96191.1 - 0.052 12.8 10.6 0.075 12.2 7.4 1.2 1 0 0 1 1 1 0 NOA36 protein Lin-8 PF03353.10 OAI96191.1 - 0.21 10.8 7.6 0.12 11.5 4.0 1.5 1 1 1 2 2 2 0 Ras-mediated vulval-induction antagonist PPP4R2 PF09184.6 OAI96191.1 - 0.42 10.1 13.3 0.67 9.4 9.2 1.3 1 0 0 1 1 1 0 PPP4R2 YL1 PF05764.8 OAI96191.1 - 0.5 9.9 21.4 0.39 10.2 14.1 1.4 1 1 0 1 1 1 0 YL1 nuclear protein VID27 PF08553.5 OAI96191.1 - 1.2 7.2 8.2 1.5 6.9 5.7 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Paf1 PF03985.8 OAI96191.1 - 1.5 7.4 11.0 2 7.0 7.6 1.2 1 0 0 1 1 1 0 Paf1 DUF1510 PF07423.6 OAI96191.1 - 1.6 8.0 13.1 2.3 7.5 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_RNA_Pol_19 PF05320.7 OAI96191.1 - 2 8.1 6.7 0.87 9.3 3.2 1.6 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit RRN3 PF05327.6 OAI96191.1 - 2.7 6.0 8.9 3.6 5.5 6.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Prothymosin PF03247.9 OAI96191.1 - 3 8.0 29.1 0.25 11.4 16.4 2.0 2 0 0 2 2 2 0 Prothymosin/parathymosin family zf-DHHC PF01529.15 OAI96199.1 - 2.7e-38 131.0 3.9 2.7e-38 131.0 2.7 1.6 1 1 1 2 2 2 1 DHHC palmitoyltransferase Zip PF02535.17 OAI96199.1 - 0.01 14.8 4.8 0.012 14.6 1.8 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Arc_PepC_II PF06847.6 OAI96199.1 - 0.15 12.4 1.3 0.43 11.0 0.9 1.7 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II RIC3 PF15361.1 OAI96199.1 - 5.3 7.2 5.6 10 6.3 1.8 2.2 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Esterase PF00756.15 OAI96218.1 - 5.1e-36 124.3 0.0 7e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 OAI96218.1 - 1e-05 25.3 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 OAI96218.1 - 0.092 11.6 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.16 OAI96218.1 - 0.12 11.5 0.1 0.79 8.9 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family MAT1 PF06391.8 OAI96220.1 - 0.39 10.2 3.5 0.62 9.6 2.4 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 TIR_2 PF13676.1 OAI96220.1 - 0.99 9.5 6.6 1.3 9.2 3.5 1.9 1 1 1 2 2 2 0 TIR domain DEAD PF00270.24 OAI96229.1 - 1.5e-16 60.3 0.0 2.5e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAI96229.1 - 3e-05 23.7 0.0 0.00019 21.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3505 PF12013.3 OAI96233.1 - 0.003 17.7 0.0 0.0083 16.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) Geminin PF07412.7 OAI96241.1 - 0.062 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Geminin UBN2_2 PF14227.1 OAI96249.1 - 8.2e-11 41.5 0.3 1.2e-10 40.9 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAI96249.1 - 1.1e-09 38.1 1.0 1.7e-09 37.5 0.7 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 OAI96249.1 - 2.4e-06 27.1 0.0 5.4e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAI96249.1 - 0.00028 20.4 0.0 0.00061 19.3 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 OAI96249.1 - 0.05 13.5 4.1 0.17 11.8 2.8 1.9 1 0 0 1 1 1 0 Zinc knuckle FHA PF00498.21 OAI96261.1 - 0.0099 15.9 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain alpha-hel2 PF14456.1 OAI96263.1 - 0.035 12.8 0.0 0.056 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha-helical domain 2 Xpo1 PF08389.7 OAI96263.1 - 0.04 13.8 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 Exportin 1-like protein NAD_binding_5 PF07994.7 OAI96265.1 - 6.7e-23 81.6 0.0 8.8e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Secretin_N_2 PF07655.8 OAI96269.1 - 0.24 11.8 4.1 3.9 7.9 0.1 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain CytochromB561_N PF09786.4 OAI96269.1 - 7.6 4.8 9.0 10 4.4 6.2 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Yae1_N PF09811.4 OAI96271.1 - 2.7e-06 26.7 9.7 2.7e-06 26.7 6.7 1.8 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Transposase_21 PF02992.9 OAI96284.1 - 0.033 13.2 1.0 1.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Transposase family tnp2 Resolvase PF00239.16 OAI96287.1 - 1.4e-23 83.3 0.0 1.5e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Resolvase, N terminal domain FYVE PF01363.16 OAI96291.1 - 6.1e-19 67.6 9.7 6.1e-19 67.6 6.7 3.0 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 OAI96291.1 - 3.4e-11 42.7 3.0 3.4e-11 42.7 2.1 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAI96291.1 - 0.0001 22.2 4.4 0.0001 22.2 3.1 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAI96291.1 - 0.0085 15.7 1.9 0.0085 15.7 1.3 3.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAI96291.1 - 0.012 15.2 3.8 0.012 15.2 2.7 3.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 OAI96291.1 - 0.017 15.2 4.5 0.017 15.2 3.1 2.9 3 1 0 3 3 3 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 OAI96291.1 - 0.038 13.7 1.7 0.038 13.7 1.2 2.8 4 0 0 4 4 4 0 RING-type zinc-finger FYVE_2 PF02318.11 OAI96291.1 - 0.44 10.4 13.3 0.13 12.1 4.5 2.6 2 1 0 2 2 2 0 FYVE-type zinc finger UPF0547 PF10571.4 OAI96291.1 - 1.2 8.9 6.6 2.5 7.8 0.0 3.9 3 2 0 3 3 3 0 Uncharacterised protein family UPF0547 HypA PF01155.14 OAI96291.1 - 2.2 8.0 9.2 1.2 8.8 2.4 2.8 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family NAD_binding_4 PF07993.7 OAI96295.1 - 1.8e-05 23.8 0.0 0.00014 20.8 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 OAI96295.1 - 0.00014 21.7 0.2 0.00065 19.6 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAI96295.1 - 0.0037 16.9 0.4 0.043 13.4 0.0 2.1 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 OAI96295.1 - 0.032 13.1 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 OAI96295.1 - 0.086 13.1 0.0 0.22 11.8 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Arena_nucleocap PF00843.12 OAI96295.1 - 0.15 9.9 0.0 0.2 9.4 0.0 1.1 1 0 0 1 1 1 0 Arenavirus nucleocapsid protein Ras PF00071.17 OAI96303.1 - 2.6e-65 218.7 0.0 3e-65 218.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAI96303.1 - 1.6e-19 70.5 0.0 2.2e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAI96303.1 - 2e-13 49.9 0.0 2.4e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAI96303.1 - 3.5e-05 23.0 0.0 4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 OAI96303.1 - 3.9e-05 23.1 0.0 0.0001 21.8 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAI96303.1 - 0.0005 20.0 0.0 0.00074 19.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 OAI96303.1 - 0.027 14.4 0.0 0.084 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.5 OAI96303.1 - 0.03 13.5 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 OAI96303.1 - 0.039 13.1 0.0 0.073 12.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 OAI96303.1 - 0.044 13.3 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 OAI96303.1 - 0.045 13.9 0.1 0.58 10.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 OAI96303.1 - 0.055 12.7 0.0 3.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.1 OAI96303.1 - 0.068 13.3 0.0 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 OAI96303.1 - 0.081 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MCM PF00493.18 OAI96303.1 - 0.12 11.1 0.0 0.36 9.5 0.0 1.7 2 0 0 2 2 2 0 MCM2/3/5 family MULE PF10551.4 OAI96315.1 - 3.8e-09 36.5 0.0 9.8e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAI96315.1 - 0.016 13.8 0.0 0.023 13.2 0.0 1.1 1 0 0 1 1 1 0 Transposase, Mutator family PHP PF02811.14 OAI96322.1 - 7.8e-10 38.8 0.0 1.7e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 PHP domain Sel1 PF08238.7 OAI96325.1 - 0.00016 22.1 13.6 0.22 12.1 0.0 5.7 7 0 0 7 7 7 2 Sel1 repeat DUF2587 PF10759.4 OAI96325.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) TPR_2 PF07719.12 OAI96325.1 - 0.038 13.9 0.0 0.46 10.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAI96325.1 - 0.04 14.6 1.7 0.46 11.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4232 PF14016.1 OAI96331.1 - 0.026 14.1 1.2 0.03 13.9 0.8 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4232) MULE PF10551.4 OAI96340.1 - 5.3e-19 68.1 0.1 1.3e-18 66.8 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 OAI96340.1 - 9.1e-05 22.9 0.1 0.00017 22.0 0.1 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain STAT_int PF02865.12 OAI96340.1 - 0.78 9.7 5.8 0.34 10.8 0.3 2.6 3 0 0 3 3 3 0 STAT protein, protein interaction domain DUF1289 PF06945.8 OAI96346.1 - 0.15 11.5 0.2 0.26 10.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) BRF1 PF07741.8 OAI96349.1 - 0.064 13.4 1.3 0.17 12.1 0.9 1.8 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Neisseria_TspB PF05616.8 OAI96350.1 - 3.5 5.8 6.7 3.8 5.7 4.6 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein RNase_H PF00075.19 OAI96353.1 - 2e-05 24.9 0.0 3.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAI96353.1 - 0.0041 16.8 0.0 0.0094 15.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like YfbU PF03887.9 OAI96354.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 YfbU domain GCIP PF13324.1 OAI96360.1 - 0.053 12.7 0.4 0.054 12.7 0.3 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.7 OAI96360.1 - 2.3 7.4 5.3 2.5 7.2 3.6 1.1 1 0 0 1 1 1 0 NOA36 protein FNIP_N PF14636.1 OAI96360.1 - 4.4 7.7 6.4 1.3 9.4 2.1 1.7 1 1 0 2 2 2 0 Folliculin-interacting protein N-terminus ICMT PF04140.9 OAI96365.1 - 8.9e-16 57.8 0.5 2.7e-15 56.3 0.4 1.7 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 OAI96365.1 - 2e-10 40.7 3.3 2e-09 37.4 2.3 2.0 1 1 0 1 1 1 1 Phospholipid methyltransferase FdhE PF04216.7 OAI96369.1 - 0.0039 16.9 1.0 0.13 11.9 0.1 2.0 2 0 0 2 2 2 2 Protein involved in formate dehydrogenase formation DcpS_C PF11969.3 OAI96369.1 - 0.046 13.9 0.0 0.062 13.5 0.0 1.2 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Glyco_hydro_45 PF02015.11 OAI96375.1 - 1.7e-07 31.5 0.0 2e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 MULE PF10551.4 OAI96384.1 - 1.9e-10 40.7 0.0 4.6e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAI96384.1 - 0.0004 19.0 0.0 0.00067 18.3 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Asp_protease_2 PF13650.1 OAI96386.1 - 0.0053 17.2 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Herpes_ORF11 PF04797.8 OAI96386.1 - 0.015 13.7 0.0 0.021 13.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus dUTPase protein gag-asp_proteas PF13975.1 OAI96386.1 - 0.041 13.7 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAI96386.1 - 0.05 13.5 0.0 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease DUF922 PF06037.6 OAI96389.1 - 0.68 9.2 7.1 0.12 11.6 2.3 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) Mur_ligase_C PF02875.16 OAI96393.1 - 0.13 12.2 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain zf-CCHC_4 PF14392.1 OAI96393.1 - 5.1 6.8 6.2 3.1 7.5 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle Asp PF00026.18 OAI96394.1 - 2.7e-15 56.4 0.0 3.2e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Retrotrans_gag PF03732.12 OAI96397.1 - 0.067 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Retrotrans_gag PF03732.12 OAI96403.1 - 0.0097 15.9 0.2 0.02 14.9 0.2 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein DUF2796 PF10986.3 OAI96407.1 - 0.42 10.5 8.6 0.57 10.1 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Bystin PF05291.6 OAI96408.1 - 0.15 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Bystin Daxx PF03344.10 OAI96408.1 - 0.84 8.0 10.6 1.1 7.6 7.4 1.2 1 0 0 1 1 1 0 Daxx Family PPP4R2 PF09184.6 OAI96408.1 - 1.2 8.5 8.6 1.6 8.2 6.0 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.7 OAI96408.1 - 9.1 4.0 13.2 11 3.8 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family Spore_coat_CotO PF14153.1 OAI96419.1 - 0.00013 21.4 14.7 0.00016 21.2 10.2 1.2 1 0 0 1 1 1 1 Spore coat protein CotO Ycf1 PF05758.7 OAI96419.1 - 0.001 16.9 7.9 0.001 16.9 5.5 1.0 1 0 0 1 1 1 1 Ycf1 CDC45 PF02724.9 OAI96419.1 - 0.0047 15.0 18.0 0.006 14.6 12.5 1.2 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.7 OAI96419.1 - 0.0049 16.2 29.0 0.0058 15.9 20.1 1.1 1 0 0 1 1 1 1 SDA1 SAPS PF04499.10 OAI96419.1 - 0.011 14.4 7.7 0.01 14.5 5.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4175 PF13779.1 OAI96419.1 - 0.056 11.1 24.2 0.067 10.8 16.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Plasmodium_Vir PF05795.6 OAI96419.1 - 0.18 11.0 5.7 0.21 10.7 4.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Nop14 PF04147.7 OAI96419.1 - 0.22 9.3 41.0 0.28 9.0 28.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4045 PF13254.1 OAI96419.1 - 1.1 8.5 12.8 1.4 8.0 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF1510 PF07423.6 OAI96419.1 - 2.5 7.3 35.0 3.4 6.9 24.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4407 PF14362.1 OAI96419.1 - 3.9 6.3 8.4 4.3 6.1 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MIP-T3 PF10243.4 OAI96419.1 - 5.9 5.2 28.9 7.8 4.8 20.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AAA PF00004.24 OAI96424.1 - 4.3e-33 114.3 0.0 6.2e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAI96424.1 - 1e-05 25.5 0.1 4.6e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 OAI96424.1 - 1.8e-05 24.4 0.2 0.00042 20.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 OAI96424.1 - 0.00021 21.4 0.1 0.0051 16.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAI96424.1 - 0.00054 19.4 0.5 0.025 13.9 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 OAI96424.1 - 0.00084 19.2 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAI96424.1 - 0.0012 18.5 0.1 0.015 15.0 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_2 PF07724.9 OAI96424.1 - 0.0018 18.1 0.0 0.013 15.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) Zot PF05707.7 OAI96424.1 - 0.0029 17.1 0.1 0.076 12.4 0.0 2.4 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_24 PF13479.1 OAI96424.1 - 0.018 14.6 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 OAI96424.1 - 0.026 13.6 0.1 0.23 10.5 0.0 2.3 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 OAI96424.1 - 0.043 14.6 0.0 0.077 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 OAI96424.1 - 0.044 13.4 0.4 8.7 6.0 0.0 2.3 1 1 0 2 2 2 0 NTPase AAA_33 PF13671.1 OAI96424.1 - 0.046 13.6 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 OAI96424.1 - 0.052 13.1 0.0 0.097 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 OAI96424.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 OAI96424.1 - 0.099 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 OAI96424.1 - 0.13 11.3 0.1 0.21 10.6 0.1 1.6 1 1 0 1 1 1 0 KaiC Arch_ATPase PF01637.13 OAI96424.1 - 0.18 11.4 0.0 0.45 10.1 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase RVT_2 PF07727.9 OAI96427.1 - 0.00027 19.9 0.1 0.00038 19.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asn_synthase PF00733.16 OAI96436.1 - 8.1e-15 55.0 0.0 1.1e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_6 PF13522.1 OAI96436.1 - 0.0062 16.5 0.0 0.064 13.2 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain NAD_synthase PF02540.12 OAI96436.1 - 0.073 11.9 0.0 0.098 11.5 0.0 1.1 1 0 0 1 1 1 0 NAD synthase SDA1 PF05285.7 OAI96445.1 - 4.5 6.4 7.0 5.6 6.1 4.8 1.1 1 0 0 1 1 1 0 SDA1 rve PF00665.21 OAI96448.1 - 8.3e-22 77.5 0.0 1.3e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 OAI96448.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 DDE domain Phage_integrase PF00589.17 OAI96458.1 - 0.00024 20.8 0.0 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Lipocalin_5 PF13924.1 OAI96458.1 - 0.036 13.7 0.1 0.085 12.5 0.1 1.6 1 0 0 1 1 1 0 Lipocalin-like domain TetR PF13972.1 OAI96475.1 - 5.7e-14 51.7 0.0 6.3e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial transcriptional repressor DUF2622 PF11080.3 OAI96475.1 - 0.086 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2622) OEP PF02321.13 OAI96476.1 - 1.2e-48 165.1 42.5 7.8e-29 100.6 9.7 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein SMC_N PF02463.14 OAI96476.1 - 0.13 11.5 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain RNA_pol_Rpb4 PF03874.11 OAI96479.1 - 1e-14 54.5 0.0 5.1e-14 52.2 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb4 PsaX PF08078.7 OAI96480.1 - 8.6 6.3 6.5 32 4.5 3.3 2.5 2 1 0 2 2 2 0 PsaX family CoA_binding PF02629.14 OAI96483.1 - 0.085 13.3 0.5 0.19 12.2 0.3 1.6 1 0 0 1 1 1 0 CoA binding domain Rad60-SLD PF11976.3 OAI96485.1 - 0.00022 20.8 0.1 0.00069 19.2 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ApoO PF09769.4 OAI96488.1 - 0.03 14.0 0.8 0.072 12.8 0.5 1.6 1 0 0 1 1 1 0 Apolipoprotein O CDK5_activator PF03261.10 OAI96488.1 - 0.91 8.7 7.3 0.38 10.0 0.4 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein DUF3464 PF11947.3 OAI96488.1 - 2.1 7.7 5.5 8.6 5.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3464) DDHD PF02862.12 OAI96488.1 - 2.9 7.6 5.3 3 7.5 2.6 1.7 2 0 0 2 2 2 0 DDHD domain Vmethyltransf PF01660.12 OAI96498.1 - 3.8e-32 111.2 0.0 4.8e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Viral methyltransferase Fungal_trans PF04082.13 OAI96500.1 - 2e-09 36.7 0.0 3.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_10 PF13374.1 OAI96500.1 - 0.68 9.9 4.4 6.5 6.8 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Sporozoite_P67 PF05642.6 OAI96500.1 - 1.8 6.3 8.3 0.032 12.1 0.9 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Med15 PF09606.5 OAI96500.1 - 5.4 5.0 20.8 0.055 11.6 7.1 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAD_binding_2 PF00890.19 OAI96509.1 - 2.6e-17 62.7 0.1 4e-17 62.1 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Asn_synthase PF00733.16 OAI96518.1 - 2.6e-08 33.6 0.0 4.3e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase HTH_28 PF13518.1 OAI96520.1 - 0.00031 20.6 0.0 0.00077 19.4 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 OAI96520.1 - 0.004 17.0 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.1 OAI96520.1 - 0.033 13.8 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain CENP-B_N PF04218.8 OAI96520.1 - 0.14 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Phage_Nu1 PF07471.7 OAI96524.1 - 0.017 14.6 2.2 0.026 13.9 1.5 1.2 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 HTH_6 PF01418.12 OAI96524.1 - 0.052 13.2 0.1 10 5.9 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family DUF4473 PF14747.1 OAI96527.1 - 0.0046 17.1 0.1 0.0089 16.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4473) Zeta_toxin PF06414.7 OAI96527.1 - 0.041 12.9 0.0 0.084 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PilO PF04350.8 OAI96531.1 - 0.038 13.8 1.0 0.047 13.5 0.7 1.1 1 0 0 1 1 1 0 Pilus assembly protein, PilO Nif11 PF07862.6 OAI96531.1 - 0.042 13.7 0.2 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function TilS PF09179.6 OAI96531.1 - 0.054 13.5 0.3 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 TilS substrate binding domain MMPL PF03176.10 OAI96531.1 - 0.089 11.4 0.2 0.098 11.3 0.1 1.0 1 0 0 1 1 1 0 MMPL family DUF1484 PF07363.6 OAI96531.1 - 0.091 13.1 1.8 0.35 11.2 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1484) WD40 PF00400.27 OAI96532.1 - 4.4e-42 140.4 1.8 8.7e-11 41.2 0.2 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 OAI96532.1 - 0.0079 15.9 0.0 4.3 7.1 0.0 3.2 1 1 2 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Coatomer_WDAD PF04053.9 OAI96543.1 - 1.6e-29 102.9 0.0 2e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region SH3_8 PF13457.1 OAI96546.1 - 0.00086 19.4 0.2 0.0013 18.8 0.1 1.2 1 0 0 1 1 1 1 SH3-like domain RR_TM4-6 PF06459.7 OAI96551.1 - 0.96 9.2 14.6 1.1 9.0 10.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.6 OAI96551.1 - 5.4 5.1 25.2 5.3 5.1 17.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Ycf1 PF05758.7 OAI96551.1 - 8.1 4.0 13.6 8.9 3.8 9.4 1.1 1 0 0 1 1 1 0 Ycf1 TMF_DNA_bd PF12329.3 OAI96558.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Retrotrans_gag PF03732.12 OAI96558.1 - 0.14 12.2 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein FAP PF07174.6 OAI96558.1 - 4.3 6.5 21.1 0.99 8.6 4.0 2.2 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) TAP_C PF03943.8 OAI96567.1 - 3.2e-10 39.2 0.0 4.8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 TAP C-terminal domain DDE_Tnp_4 PF13359.1 OAI96573.1 - 9.1e-20 70.8 0.0 2.1e-19 69.6 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease CinA PF02464.12 OAI96575.1 - 0.087 12.2 0.2 2.5 7.5 0.1 2.2 2 0 0 2 2 2 0 Competence-damaged protein PEMT PF04191.8 OAI96581.1 - 3.2e-34 117.2 5.8 3.2e-34 117.2 4.0 1.4 2 0 0 2 2 2 1 Phospholipid methyltransferase EI24 PF07264.6 OAI96581.1 - 0.0051 16.2 6.6 0.0092 15.4 3.9 1.7 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) DUF1510 PF07423.6 OAI96590.1 - 0.12 11.7 11.3 0.13 11.5 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 OAI96590.1 - 0.41 8.2 11.5 0.41 8.3 8.0 1.0 1 0 0 1 1 1 0 Ycf1 Tom37_C PF11801.3 OAI96590.1 - 0.57 10.0 6.7 0.71 9.7 4.7 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF3381 PF11861.3 OAI96590.1 - 4.9 6.6 18.0 6.9 6.1 12.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CDC45 PF02724.9 OAI96590.1 - 5.4 4.9 12.1 5.4 4.9 8.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Usp PF00582.21 OAI96590.1 - 7.5 6.7 7.8 13 5.9 5.4 1.5 1 1 0 1 1 1 0 Universal stress protein family GRA6 PF05084.8 OAI96590.1 - 8.4 5.8 7.7 13 5.2 5.4 1.3 1 1 0 1 1 1 0 Granule antigen protein (GRA6) FAM176 PF14851.1 OAI96590.1 - 9.3 5.9 10.1 13 5.4 7.0 1.3 1 0 0 1 1 1 0 FAM176 family TctB PF07331.6 OAI96602.1 - 0.029 14.0 0.2 0.031 13.9 0.1 1.2 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF2976 PF11190.3 OAI96602.1 - 0.21 11.1 1.4 0.24 10.9 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) Fructosamin_kin PF03881.9 OAI96613.1 - 5.6e-62 209.3 0.0 9.2e-62 208.6 0.0 1.3 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 OAI96613.1 - 1.2e-08 34.9 0.0 1.8e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family UCH PF00443.24 OAI96616.1 - 0.047 12.8 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Histone PF00125.19 OAI96619.1 - 3.4e-20 71.9 0.1 5.3e-20 71.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RRM_1 PF00076.17 OAI96626.1 - 1.3e-10 40.7 0.0 3.5e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAI96626.1 - 1.8e-08 34.2 0.0 2.7e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAI96626.1 - 1.9e-05 24.3 0.0 3.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1_C PF08265.6 OAI96627.1 - 6.7e-14 51.1 0.3 1e-13 50.5 0.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Pyr_redox_3 PF13738.1 OAI96635.1 - 4.5e-25 88.9 0.0 2.2e-24 86.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAI96635.1 - 6.7e-11 41.0 0.0 1.1e-09 37.0 0.0 2.3 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAI96635.1 - 1.2e-09 38.0 0.0 2.2e-08 33.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAI96635.1 - 1.6e-09 37.9 0.0 1.3e-07 31.6 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAI96635.1 - 2e-07 30.2 0.0 0.00064 18.7 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 OAI96635.1 - 6.7e-06 25.2 0.1 0.0028 16.6 0.1 3.6 3 1 0 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAI96635.1 - 1.9e-05 23.8 0.1 0.00019 20.6 0.0 2.3 3 0 0 3 3 3 1 Thi4 family NAD_binding_9 PF13454.1 OAI96635.1 - 7.6e-05 22.5 0.9 0.48 10.1 0.0 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 OAI96635.1 - 0.00033 19.6 0.1 0.0016 17.3 0.0 2.1 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.7 OAI96635.1 - 0.00047 19.1 0.1 0.081 11.8 0.0 2.6 2 0 0 2 2 2 1 Lycopene cyclase protein Shikimate_DH PF01488.15 OAI96635.1 - 0.0018 18.4 0.0 1.8 8.6 0.0 2.7 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Mqo PF06039.10 OAI96635.1 - 0.0036 15.5 0.2 0.62 8.1 0.0 2.6 2 1 1 3 3 3 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.22 OAI96635.1 - 0.011 16.1 0.0 7.2 7.0 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAI96635.1 - 0.023 13.5 0.2 1.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 OAI96635.1 - 0.14 11.1 0.3 0.4 9.6 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 OAI96635.1 - 0.17 10.2 0.3 0.67 8.3 0.0 2.1 3 0 0 3 3 3 0 HI0933-like protein Abhydrolase_5 PF12695.2 OAI96636.1 - 4e-07 29.8 0.2 8.1e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAI96636.1 - 0.00019 21.3 0.4 0.00032 20.6 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAI96636.1 - 0.043 13.3 0.1 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1749 PF08538.5 OAI96636.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF3464 PF11947.3 OAI96639.1 - 1.3 8.4 13.9 0.018 14.4 2.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Neur_chan_memb PF02932.11 OAI96639.1 - 9.9 5.9 15.8 9 6.0 3.2 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MMS19_C PF12460.3 OAI96642.1 - 8.2e-09 34.6 1.7 4.3e-08 32.3 0.3 1.9 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal HEAT PF02985.17 OAI96642.1 - 0.013 15.5 2.5 0.11 12.6 0.0 3.2 3 1 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.1 OAI96642.1 - 0.1 12.8 0.4 2 8.7 0.1 2.2 2 0 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.1 OAI96642.1 - 0.29 11.6 3.5 1.7 9.2 0.4 2.6 2 0 0 2 2 2 0 HEAT-like repeat Sulfate_tra_GLY PF13792.1 OAI96643.1 - 0.037 13.7 0.9 0.27 10.9 0.4 2.3 2 0 0 2 2 2 0 Sulfate transporter N-terminal domain with GLY motif RVT_1 PF00078.22 OAI96648.1 - 5.5e-20 71.6 0.0 9.3e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Trypsin_2 PF13365.1 OAI96656.1 - 0.0098 15.8 0.0 0.17 11.8 0.0 2.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain ORC6 PF05460.8 OAI96660.1 - 0.57 9.2 7.7 0.018 14.1 1.1 1.7 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF4231 PF14015.1 OAI96663.1 - 0.084 12.8 1.2 0.17 11.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Phosducin PF02114.11 OAI96667.1 - 1.3e-08 33.8 0.1 2.9e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 Phosducin Apc9 PF12856.2 OAI96667.1 - 0.4 10.8 2.9 0.92 9.6 0.3 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 9 PBP1_TM PF14812.1 OAI96667.1 - 0.97 9.7 13.1 1.2 9.4 4.9 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 OAI96667.1 - 1.2 8.6 4.5 1 8.8 0.6 2.2 2 0 0 2 2 2 0 Nucleoplasmin DDE_1 PF03184.14 OAI96669.1 - 4.6e-33 114.1 0.0 7.7e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAI96669.1 - 9.1e-06 25.4 0.1 7.4e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain rve PF00665.21 OAI96671.1 - 0.021 14.9 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain Apolipoprotein PF01442.13 OAI96675.1 - 0.00079 18.9 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 OAI96675.1 - 0.043 14.2 0.3 0.043 14.2 0.2 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) LysR_substrate PF03466.15 OAI96677.1 - 1.4e-25 89.6 1.2 2.1e-25 89.0 0.8 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.22 OAI96677.1 - 2.2e-21 75.3 0.3 2.2e-21 75.3 0.2 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.2 OAI96677.1 - 0.0023 17.7 0.7 0.012 15.3 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.2 OAI96677.1 - 0.045 13.4 0.4 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.1 OAI96677.1 - 0.085 12.2 0.1 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF3905 PF13045.1 OAI96678.1 - 0.076 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3905) LysR_substrate PF03466.15 OAI96679.1 - 7e-14 51.4 1.4 8.3e-14 51.1 1.0 1.0 1 0 0 1 1 1 1 LysR substrate binding domain IlvN PF07991.7 OAI96683.1 - 6.3e-47 159.0 0.0 1.4e-46 157.8 0.0 1.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 OAI96683.1 - 4.6e-41 140.1 0.0 7e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 OAI96683.1 - 0.063 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 OAI96683.1 - 0.098 13.0 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Dicty_REP PF05086.7 OAI96689.1 - 0.19 9.4 0.9 0.19 9.4 0.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Methyltransf_2 PF00891.13 OAI96693.1 - 5.3e-28 97.8 0.0 9.5e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 OAI96693.1 - 0.00058 20.2 0.0 0.0014 19.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAI96693.1 - 0.016 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 OAI96693.1 - 0.016 14.7 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain HTH_AraC PF00165.18 OAI96693.1 - 0.018 14.8 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Methyltransf_18 PF12847.2 OAI96693.1 - 0.043 14.4 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RPA_C PF08784.6 OAI96693.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Replication protein A C terminal Rrf2 PF02082.15 OAI96693.1 - 0.054 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator DBD_Tnp_Mut PF03108.10 OAI96697.1 - 2.2e-07 30.3 0.0 4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 MuDR family transposase MULE PF10551.4 OAI96697.1 - 1.2e-06 28.5 0.1 3.2e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 MULE transposase domain Hydrolase PF00702.21 OAI96705.1 - 9.8e-07 29.4 0.1 3.2e-06 27.6 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAI96705.1 - 0.00083 19.0 0.2 0.0012 18.4 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pro_isomerase PF00160.16 OAI96711.1 - 1.6e-47 161.5 0.7 1.9e-47 161.3 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_2 PF00152.15 OAI96716.1 - 2.6e-29 102.0 1.0 3.7e-29 101.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAI96716.1 - 8.4e-06 25.5 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SH3_2 PF07653.12 OAI96718.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 1 0 1 1 1 0 Variant SH3 domain Acetyltransf_7 PF13508.1 OAI96719.1 - 0.00024 21.2 0.0 0.00065 19.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Mito_carr PF00153.22 OAI96727.1 - 1.4e-12 47.1 0.5 2.8e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein RVT_3 PF13456.1 OAI96730.1 - 0.023 14.4 0.3 0.14 11.9 0.1 2.4 3 0 0 3 3 3 0 Reverse transcriptase-like DUF2215 PF10225.4 OAI96743.1 - 0.025 14.0 0.1 0.042 13.3 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF3306 PF11748.3 OAI96743.1 - 0.66 10.6 8.0 0.84 10.3 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Peptidase_M43 PF05572.8 OAI96745.1 - 1.5e-11 44.1 0.0 2.7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 OAI96745.1 - 0.00033 21.1 1.0 0.0011 19.4 0.7 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAI96745.1 - 0.00065 19.6 0.6 0.00096 19.1 0.4 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 OAI96745.1 - 0.0034 17.4 1.0 0.0052 16.8 0.6 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 OAI96745.1 - 0.016 14.9 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Matrixin Peptidase_M7 PF02031.11 OAI96745.1 - 0.023 14.3 1.1 0.023 14.3 0.8 1.7 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_4 PF13583.1 OAI96745.1 - 0.026 14.0 0.1 0.046 13.2 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Abhydrolase_5 PF12695.2 OAI96751.1 - 3e-08 33.5 0.0 4.7e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAI96751.1 - 4.5e-08 33.2 0.2 0.00046 20.1 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAI96751.1 - 2.5e-05 23.9 0.1 0.22 11.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 OAI96751.1 - 0.062 12.7 3.6 0.76 9.1 0.4 2.5 2 1 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) VID27 PF08553.5 OAI96754.1 - 1.6e-119 400.3 0.1 2e-119 400.1 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein TPR_12 PF13424.1 OAI96755.1 - 3.2e-06 26.9 18.2 0.019 14.8 0.0 5.6 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAI96755.1 - 3.2e-05 23.4 12.7 3.2 7.8 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 OAI96755.1 - 0.0018 17.8 0.9 3.6 7.3 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat UNC45-central PF11701.3 OAI96755.1 - 0.0022 17.6 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central TPR_11 PF13414.1 OAI96755.1 - 0.0047 16.5 10.6 0.57 9.8 0.0 4.9 4 2 1 5 5 5 2 TPR repeat TPR_19 PF14559.1 OAI96755.1 - 0.51 10.7 12.1 13 6.1 0.0 5.9 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAI96755.1 - 1.2 9.9 18.1 54 4.8 0.0 7.5 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAI96755.1 - 7.9 7.1 9.7 11 6.7 0.1 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAI96755.1 - 9.8 6.9 17.4 1.6 9.4 0.1 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat tRNA-synt_1 PF00133.17 OAI96757.1 - 6.2e-53 179.7 0.0 1.3e-52 178.6 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 OAI96757.1 - 4e-23 81.8 0.0 6.5e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 OAI96757.1 - 9.4e-05 21.2 0.0 0.00013 20.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 OAI96757.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Hydrolase PF00702.21 OAI96763.1 - 2e-06 28.3 0.0 3.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAI96763.1 - 0.0027 17.8 0.0 0.0038 17.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAI96763.1 - 0.033 14.1 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Axin_b-cat_bind PF08833.5 OAI96763.1 - 8.4 6.1 8.9 0.92 9.2 1.6 2.9 2 0 0 2 2 2 0 Axin beta-catenin binding domain LSM PF01423.17 OAI96776.1 - 4e-17 61.5 0.1 5.6e-17 61.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain PTPA PF03095.10 OAI96777.1 - 1.4e-87 293.7 0.0 1.7e-87 293.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein YqaJ PF09588.5 OAI96777.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain DC_STAMP PF07782.8 OAI96780.1 - 0.057 13.0 0.9 4.2 6.9 0.0 2.2 1 1 0 2 2 2 0 DC-STAMP-like protein KAR9 PF08580.5 OAI96781.1 - 1.2 7.2 10.1 2.2 6.4 0.0 2.1 1 1 0 2 2 2 0 Yeast cortical protein KAR9 Viral_helicase1 PF01443.13 OAI96787.1 - 4.1e-15 55.9 0.0 5.3e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 OAI96787.1 - 0.026 13.9 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 OAI96787.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ETX_MTX2 PF03318.8 OAI96787.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 DUF572 PF04502.8 OAI96797.1 - 0.6 9.2 13.2 0.78 8.9 9.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) BBP1_C PF15272.1 OAI96797.1 - 1.1 8.7 13.3 1.8 8.1 9.2 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Vfa1 PF08432.5 OAI96797.1 - 2.4 8.1 14.1 3.7 7.5 9.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3584 PF12128.3 OAI96797.1 - 2.5 5.3 15.6 3.2 4.9 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EF-hand_like PF09279.6 OAI96801.1 - 0.052 13.5 0.2 0.06 13.3 0.2 1.1 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Pyr_redox_2 PF07992.9 OAI96802.1 - 7.3e-29 101.0 0.2 8.9e-29 100.8 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAI96802.1 - 4.7e-18 65.3 0.1 3e-15 56.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAI96802.1 - 3.5e-08 33.7 0.1 0.00085 19.4 0.0 3.1 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAI96802.1 - 1.5e-06 27.4 0.1 9e-05 21.6 0.0 2.5 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 OAI96802.1 - 3.8e-06 26.2 0.0 0.038 13.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 OAI96802.1 - 2.2e-05 23.5 2.0 0.0053 15.6 0.1 3.5 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 OAI96802.1 - 4.1e-05 22.8 0.2 0.036 13.1 0.0 3.0 2 1 1 3 3 3 1 FAD binding domain DAO PF01266.19 OAI96802.1 - 0.0001 21.3 3.1 0.006 15.5 0.0 3.3 2 2 2 4 4 4 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 OAI96802.1 - 0.00013 22.1 0.2 0.0098 16.1 0.0 2.9 2 2 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 OAI96802.1 - 0.00014 21.7 0.4 0.0097 15.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 OAI96802.1 - 0.00018 21.6 0.0 0.14 12.3 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 OAI96802.1 - 0.0019 17.1 3.9 0.005 15.7 0.3 2.5 2 1 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 OAI96802.1 - 0.0037 15.9 0.1 0.053 12.1 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.9 OAI96802.1 - 0.0045 15.5 0.1 0.028 12.9 0.1 2.3 3 0 0 3 3 3 1 HI0933-like protein K_oxygenase PF13434.1 OAI96802.1 - 0.0045 15.9 0.0 0.57 9.0 0.0 3.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 OAI96802.1 - 0.024 14.2 0.2 0.095 12.2 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Cro PF09048.5 OAI96805.1 - 0.051 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Cro Sec15 PF04091.7 OAI96807.1 - 1.1e-38 133.3 0.0 1.3e-38 133.1 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like 4HBT_3 PF13622.1 OAI96811.1 - 0.067 12.9 1.2 0.68 9.6 0.8 2.1 1 1 0 1 1 1 0 Thioesterase-like superfamily PPP4R2 PF09184.6 OAI96811.1 - 1.9 7.9 9.0 2.7 7.4 6.3 1.1 1 0 0 1 1 1 0 PPP4R2 DUF11 PF01345.13 OAI96811.1 - 3.1 7.8 6.0 31 4.7 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF11 DUF3288 PF11691.3 OAI96813.1 - 0.032 13.9 0.1 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3288) RVT_1 PF00078.22 OAI96819.1 - 7.5e-22 77.7 0.0 9.6e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1232 PF06803.7 OAI96819.1 - 0.23 10.9 1.4 0.66 9.4 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) PAD_porph PF04371.10 OAI96822.1 - 0.0038 16.3 0.7 0.22 10.5 0.1 2.1 1 1 1 2 2 2 2 Porphyromonas-type peptidyl-arginine deiminase ATP-synt_S1 PF05827.7 OAI96823.1 - 0.029 13.7 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Methyltransf_4 PF02390.12 OAI96825.1 - 5.5e-50 169.1 0.0 7.2e-38 129.6 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 OAI96825.1 - 0.008 16.7 0.2 0.12 12.9 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAI96825.1 - 0.021 15.2 0.0 0.077 13.4 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 OAI96825.1 - 0.044 14.1 0.1 0.16 12.3 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Glycos_transf_2 PF00535.21 OAI96825.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Collagen PF01391.13 OAI96827.1 - 2.1e-23 81.6 82.0 1.3e-10 40.6 27.5 3.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) CH PF00307.26 OAI96831.1 - 1.7e-07 31.2 0.1 2e-07 31.0 0.1 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain Yos1 PF08571.5 OAI96832.1 - 5.5e-28 96.8 1.4 7e-28 96.5 1.0 1.1 1 0 0 1 1 1 1 Yos1-like HNH PF01844.18 OAI96839.1 - 0.015 15.1 0.4 0.07 13.0 0.1 2.1 2 0 0 2 2 2 0 HNH endonuclease Exo_endo_phos_2 PF14529.1 OAI96841.1 - 1.7e-12 46.9 0.0 3.1e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAI96841.1 - 7.1e-06 26.1 0.1 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NIT PF08376.5 OAI96841.1 - 0.0043 16.6 1.4 0.0094 15.4 0.6 1.7 1 1 0 1 1 1 1 Nitrate and nitrite sensing RVT_3 PF13456.1 OAI96843.1 - 0.026 14.2 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like RVT_1 PF00078.22 OAI96843.1 - 0.037 13.3 0.0 0.085 12.2 0.0 1.5 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AMP-binding PF00501.23 OAI96849.1 - 2.2e-05 23.0 0.0 2.6e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Actin PF00022.14 OAI96855.1 - 1.2e-158 527.7 0.0 1.3e-158 527.5 0.0 1.0 1 0 0 1 1 1 1 Actin Methyltransf_29 PF03141.11 OAI96855.1 - 0.026 12.8 0.0 0.036 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ESSS PF10183.4 OAI96855.1 - 0.073 13.4 0.0 0.17 12.3 0.0 1.6 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) BLOC1_2 PF10046.4 OAI96859.1 - 0.024 14.7 3.8 0.03 14.4 2.3 1.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 OAI96859.1 - 0.036 13.1 6.2 0.04 12.9 4.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 HSP70 PF00012.15 OAI96859.1 - 0.58 7.9 7.7 0.67 7.7 5.3 1.0 1 0 0 1 1 1 0 Hsp70 protein AAA_23 PF13476.1 OAI96859.1 - 0.67 10.2 4.9 0.8 9.9 3.4 1.2 1 0 0 1 1 1 0 AAA domain XkdW PF09636.5 OAI96859.1 - 0.78 9.6 8.4 0.31 10.9 1.2 2.1 1 1 1 2 2 2 0 XkdW protein DUF4072 PF13284.1 OAI96865.1 - 0.037 14.1 0.1 0.057 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) FHA PF00498.21 OAI96870.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 FHA domain FHA PF00498.21 OAI96876.1 - 0.092 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 FHA domain adh_short PF00106.20 OAI96879.1 - 1.4e-07 31.5 0.0 2.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAI96879.1 - 0.021 14.4 0.1 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 KR domain rve PF00665.21 OAI96886.1 - 1.5e-20 73.4 0.0 3.4e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAI96886.1 - 0.00021 20.7 0.0 0.00021 20.7 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain Omp28 PF11551.3 OAI96886.1 - 0.046 13.2 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein Omp28 Histone PF00125.19 OAI96898.1 - 0.00022 21.2 0.5 0.00042 20.3 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 BON PF04972.12 OAI96898.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 BON domain DUF45 PF01863.12 OAI96914.1 - 4.1e-49 167.1 0.6 1.2e-48 165.6 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF45 WLM PF08325.5 OAI96914.1 - 4e-07 30.0 0.7 1.6e-06 28.1 0.1 2.1 2 0 0 2 2 2 1 WLM domain SprT-like PF10263.4 OAI96914.1 - 4e-05 23.3 0.4 0.00011 21.9 0.2 1.7 1 0 0 1 1 1 1 SprT-like family RimK PF08443.6 OAI96914.1 - 0.018 14.5 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain DUF1320 PF07030.7 OAI96914.1 - 5.2 6.8 7.2 29 4.4 0.1 4.1 2 2 2 4 4 4 0 Protein of unknown function (DUF1320) MS_channel PF00924.13 OAI96917.1 - 1.2e-10 41.0 5.9 1.4e-08 34.3 4.1 2.2 1 1 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.1 OAI96917.1 - 0.011 15.8 0.0 0.03 14.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 OAI96917.1 - 0.026 13.8 0.0 0.074 12.3 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 OAI96917.1 - 0.15 12.0 0.0 0.64 10.0 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain Transposase_21 PF02992.9 OAI96920.1 - 2.1e-07 30.2 0.0 2.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 RVT_1 PF00078.22 OAI96923.1 - 2.5e-13 49.9 0.0 4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAI96923.1 - 6.7e-13 49.1 0.0 1.2e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAI96923.1 - 0.024 14.4 0.0 0.2 11.4 0.0 2.3 1 1 0 1 1 1 0 Reverse transcriptase-like DUF2404 PF10296.4 OAI96926.1 - 0.00014 21.8 0.0 0.0003 20.8 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF3682 PF12446.3 OAI96927.1 - 0.066 13.5 5.8 0.086 13.1 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) FliX PF10768.4 OAI96927.1 - 0.12 12.5 0.5 0.16 12.1 0.4 1.2 1 0 0 1 1 1 0 Class II flagellar assembly regulator SR-25 PF10500.4 OAI96927.1 - 0.29 10.5 6.2 0.37 10.2 4.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein His_Phos_1 PF00300.17 OAI96928.1 - 2.8e-06 27.5 0.0 3.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2072 PF09845.4 OAI96933.1 - 0.2 11.5 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) SAM_decarbox PF01536.11 OAI96936.1 - 1.9e-78 263.4 0.0 3.4e-77 259.3 0.0 2.6 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase EF-hand_10 PF14788.1 OAI96939.1 - 0.0016 18.0 0.2 0.0033 17.0 0.1 1.5 1 0 0 1 1 1 1 EF hand SQS_PSY PF00494.14 OAI96939.1 - 0.047 12.9 0.8 0.067 12.4 0.3 1.5 2 0 0 2 2 2 0 Squalene/phytoene synthase HEPN PF05168.9 OAI96939.1 - 0.081 12.8 0.1 0.23 11.3 0.0 1.7 1 1 0 1 1 1 0 HEPN domain HBS1_N PF08938.5 OAI96939.1 - 0.099 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 HBS1 N-terminus RRM_1 PF00076.17 OAI96941.1 - 7.5e-37 124.8 0.0 6.4e-16 57.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAI96941.1 - 9e-21 73.6 0.0 1.4e-07 31.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAI96941.1 - 8.5e-07 28.7 0.0 0.0061 16.3 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 OAI96941.1 - 0.19 9.5 31.3 0.31 8.8 21.7 1.3 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.10 OAI96941.1 - 0.27 9.8 8.3 0.47 9.0 5.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NOA36 PF06524.7 OAI96941.1 - 9.8 5.3 20.5 20 4.2 14.2 1.5 1 0 0 1 1 1 0 NOA36 protein Phage_integrase PF00589.17 OAI96946.1 - 0.00092 18.9 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF4431 PF14485.1 OAI96946.1 - 0.16 11.6 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) BCDHK_Adom3 PF10436.4 OAI96952.1 - 5e-05 22.8 0.1 8.3e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Mito_carr PF00153.22 OAI96956.1 - 9.3e-64 211.1 2.7 9.7e-20 70.0 0.0 4.6 3 1 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 OAI96956.1 - 0.016 15.0 0.3 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 UcrQ family DUF164 PF02591.10 OAI96956.1 - 0.14 12.0 0.0 0.46 10.3 0.0 1.9 1 0 0 1 1 1 0 Putative zinc ribbon domain Retrotrans_gag PF03732.12 OAI96958.1 - 0.033 14.2 0.1 0.11 12.5 0.1 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Zn_clus PF00172.13 OAI96961.1 - 0.00043 20.1 15.1 0.00062 19.6 10.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain U3snoRNP10 PF12397.3 OAI96966.1 - 0.039 13.9 0.1 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 Methyltransf_2 PF00891.13 OAI96969.1 - 7.1e-16 58.1 0.0 1.1e-15 57.4 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase DDE_1 PF03184.14 OAI96974.1 - 2.1e-32 112.0 0.1 5.9e-32 110.5 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAI96974.1 - 2.5e-08 33.5 0.1 2.5e-08 33.5 0.0 2.7 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain rve PF00665.21 OAI96977.1 - 1.2e-12 47.9 0.0 2.4e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain MobB PF03205.9 OAI96982.1 - 0.13 11.9 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PfkB PF00294.19 OAI96986.1 - 2.6e-59 200.8 0.3 3.1e-59 200.5 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 OAI96986.1 - 0.00059 19.1 0.0 0.0014 17.8 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DUF3245 PF11595.3 OAI96988.1 - 0.14 12.4 1.1 0.31 11.3 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Nucleoporin_FG PF13634.1 OAI96991.1 - 1.7 8.8 11.8 0.12 12.5 4.5 1.7 2 0 0 2 2 2 0 Nucleoporin FG repeat region MULE PF10551.4 OAI96993.1 - 6.9e-08 32.5 0.0 1.8e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain TrkA_N PF02254.13 OAI96993.1 - 0.061 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain His_binding PF02098.11 OAI96993.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Tick histamine binding protein rve PF00665.21 OAI96996.1 - 1.2e-19 70.5 0.0 2.5e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAI96996.1 - 0.0048 16.3 0.0 0.017 14.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.9 OAI97003.1 - 5.1e-77 258.1 0.0 6.8e-77 257.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF726 PF05277.7 OAI97012.1 - 1.4e-62 211.5 0.1 1.9e-62 211.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 OAI97012.1 - 0.0008 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family FliD_N PF02465.13 OAI97017.1 - 0.0046 17.2 0.4 0.014 15.7 0.3 1.7 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 N-terminus Peptidase_S10 PF00450.17 OAI97025.1 - 1.8e-72 244.8 0.1 2.4e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase MT-A70 PF05063.9 OAI97029.1 - 2e-07 30.7 0.0 0.0087 15.6 0.1 3.4 2 1 0 2 2 2 2 MT-A70 FUSC PF04632.7 OAI97046.1 - 0.22 9.9 0.9 0.29 9.5 0.5 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF3347 PF11827.3 OAI97046.1 - 1 9.3 6.3 0.34 10.9 2.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) rve_3 PF13683.1 OAI97051.1 - 0.084 12.4 0.0 0.19 11.2 0.0 1.7 1 1 1 2 2 2 0 Integrase core domain Sec1 PF00995.18 OAI97055.1 - 1.3e-98 331.0 0.0 2.3e-98 330.2 0.0 1.3 1 1 0 1 1 1 1 Sec1 family YlbD_coat PF14071.1 OAI97055.1 - 0.012 15.6 0.1 0.029 14.4 0.1 1.6 1 0 0 1 1 1 0 Putative coat protein Peptidase_C48 PF02902.14 OAI97059.1 - 6.3e-08 32.5 0.5 5.4e-07 29.4 0.0 2.4 1 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain WD40 PF00400.27 OAI97060.1 - 4.3e-05 23.2 17.7 0.053 13.4 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoplasmin PF03066.10 OAI97060.1 - 0.13 11.8 2.3 0.2 11.1 1.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 OAI97060.1 - 0.29 11.3 8.8 0.7 10.1 6.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SWIM PF04434.12 OAI97064.1 - 0.00092 18.6 0.5 0.0015 17.9 0.4 1.4 1 0 0 1 1 1 1 SWIM zinc finger Asp_protease_2 PF13650.1 OAI97072.1 - 0.0016 18.8 0.0 0.0035 17.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI97072.1 - 0.022 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI97072.1 - 0.046 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 OAI97072.1 - 0.051 12.9 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF165 PF02592.10 OAI97073.1 - 0.0081 16.3 0.5 0.0081 16.3 0.3 1.9 3 0 0 3 3 3 1 Uncharacterized ACR, YhhQ family COG1738 HSBP1 PF06825.7 OAI97084.1 - 4.6e-12 45.3 0.0 5.1e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF1515 PF07439.6 OAI97084.1 - 0.031 14.0 0.0 0.035 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) HR1 PF02185.11 OAI97084.1 - 0.11 12.2 0.7 0.13 12.0 0.5 1.3 1 1 0 1 1 1 0 Hr1 repeat YvrJ PF12841.2 OAI97084.1 - 0.12 11.6 0.2 0.39 10.0 0.1 1.8 1 1 1 2 2 2 0 YvrJ protein family FlaC_arch PF05377.6 OAI97084.1 - 0.12 12.2 0.5 0.19 11.6 0.3 1.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DELLA PF12041.3 OAI97084.1 - 0.21 11.2 0.9 9.8 5.9 0.0 2.1 1 1 1 2 2 2 0 Transcriptional regulator DELLA protein N terminal PXB PF12828.2 OAI97085.1 - 7.3e-40 135.7 0.2 1.1e-39 135.1 0.1 1.2 1 0 0 1 1 1 1 PX-associated PX PF00787.19 OAI97085.1 - 1.2e-05 25.0 0.1 3.9e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 PX domain rve PF00665.21 OAI97088.1 - 5.5e-13 49.0 0.0 5.7e-12 45.8 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_3 PF13456.1 OAI97088.1 - 0.0018 18.0 0.3 0.018 14.8 0.0 2.7 3 0 0 3 3 3 1 Reverse transcriptase-like Cupin_4 PF08007.7 OAI97091.1 - 3e-47 161.4 0.1 3.8e-47 161.0 0.1 1.0 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 OAI97091.1 - 1.8e-11 44.0 0.2 1e-09 38.2 0.0 2.5 1 1 0 2 2 2 1 Cupin-like domain Cupin_2 PF07883.6 OAI97091.1 - 0.04 13.4 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 Cupin domain tRNA_NucTran2_2 PF13735.1 OAI97091.1 - 0.07 12.9 0.0 1.1 9.0 0.0 2.5 3 0 0 3 3 3 0 tRNA nucleotidyltransferase domain 2 putative Y1_Tnp PF01797.11 OAI97097.1 - 0.064 13.1 0.3 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 Transposase IS200 like ADH_zinc_N_2 PF13602.1 OAI97109.1 - 1.8e-17 64.4 0.0 5.6e-17 62.8 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 OAI97109.1 - 5.3e-17 61.5 0.3 1.1e-16 60.6 0.2 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAI97109.1 - 4.6e-10 39.2 0.0 1.2e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 OAI97109.1 - 0.013 15.1 0.2 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 OAI97109.1 - 0.045 13.3 0.1 0.079 12.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CMAS PF02353.15 OAI97109.1 - 0.06 12.4 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase SSB PF00436.20 OAI97109.1 - 0.085 12.7 0.3 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 Single-strand binding protein family 2-Hacid_dh_C PF02826.14 OAI97109.1 - 0.16 11.0 0.2 0.33 10.0 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 OAI97112.1 - 1.1e-14 55.3 0.0 3.2e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 OAI97112.1 - 1.6e-13 50.3 0.0 2.8e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DeoRC PF00455.17 OAI97112.1 - 0.0032 17.1 0.1 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 DeoR C terminal sensor domain ADH_N PF08240.7 OAI97112.1 - 0.0048 16.6 0.0 0.037 13.7 0.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Ima1_N PF09779.4 OAI97122.1 - 2 8.9 6.6 4.1 7.8 0.2 3.0 2 0 0 2 2 2 0 Ima1 N-terminal domain MitMem_reg PF13012.1 OAI97125.1 - 4.8e-20 71.7 0.0 8.5e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 OAI97125.1 - 6.9e-17 61.2 0.0 1.5e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RNase_PH PF01138.16 OAI97128.1 - 4e-16 59.5 0.0 6.8e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 3Beta_HSD PF01073.14 OAI97129.1 - 8.3e-20 70.6 0.0 3.2e-19 68.6 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAI97129.1 - 3e-16 59.5 0.0 3.7e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAI97129.1 - 1.9e-12 47.5 0.0 3.4e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAI97129.1 - 5.2e-12 45.2 0.9 4.7e-11 42.1 0.6 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 OAI97129.1 - 6.3e-08 32.1 0.1 9.2e-08 31.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 OAI97129.1 - 5.1e-05 22.3 0.1 9.3e-05 21.4 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 OAI97129.1 - 0.00096 19.1 0.4 0.0037 17.1 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_2 PF03446.10 OAI97129.1 - 0.005 16.6 0.0 0.012 15.4 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 OAI97129.1 - 0.016 14.5 0.1 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain KR PF08659.5 OAI97129.1 - 0.017 14.7 0.8 0.33 10.6 0.6 2.2 1 1 0 1 1 1 0 KR domain RVT_3 PF13456.1 OAI97134.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like RVT_3 PF13456.1 OAI97137.1 - 0.022 14.5 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like DNA_pol_viral_C PF00336.13 OAI97137.1 - 0.031 13.5 0.1 0.067 12.4 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Phage_integrase PF00589.17 OAI97138.1 - 6.9e-05 22.5 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF4431 PF14485.1 OAI97138.1 - 0.099 12.2 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) FHA PF00498.21 OAI97143.1 - 0.14 12.3 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 FHA domain RmlD_sub_bind PF04321.12 OAI97150.1 - 0.038 12.8 0.2 0.078 11.8 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Cornifin PF02389.10 OAI97150.1 - 0.094 12.4 8.9 0.12 12.1 6.2 1.2 1 0 0 1 1 1 0 Cornifin (SPRR) family SR-25 PF10500.4 OAI97150.1 - 0.38 10.2 15.5 0.52 9.7 10.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 OAI97150.1 - 0.86 7.8 6.8 1 7.5 4.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Apt1 PF10351.4 OAI97150.1 - 0.9 8.3 2.9 1.1 8.0 2.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pol_alpha_B_N PF08418.5 OAI97150.1 - 0.93 8.9 7.8 1.2 8.6 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal TMEM154 PF15102.1 OAI97150.1 - 4.3 7.0 6.5 7.2 6.3 4.5 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF1014 PF06244.7 OAI97152.1 - 5.1e-13 49.2 4.5 4.6e-10 39.7 2.1 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF1014) CheZ PF04344.8 OAI97152.1 - 0.064 12.9 0.1 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ CMS1 PF14617.1 OAI97156.1 - 1.6e-19 69.9 3.1 2e-09 36.8 0.3 4.2 2 2 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 OAI97156.1 - 0.1 12.0 0.0 0.28 10.6 0.0 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase BRF1 PF07741.8 OAI97156.1 - 8.9 6.6 8.1 5.1 7.3 0.4 3.0 3 0 0 3 3 3 0 Brf1-like TBP-binding domain BBE PF08031.7 OAI97157.1 - 0.00092 19.0 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Berberine and berberine like DUF4218 PF13960.1 OAI97165.1 - 0.0088 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Histone PF00125.19 OAI97166.1 - 5.1e-29 100.2 0.4 8.3e-29 99.5 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAI97166.1 - 0.00062 19.9 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S MannoseP_isomer PF01050.13 OAI97166.1 - 0.07 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase BATS PF06968.8 OAI97179.1 - 3.1e-26 91.0 0.1 1.2e-25 89.1 0.0 2.1 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 OAI97179.1 - 3.5e-13 50.0 0.1 5.7e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily SPX PF03105.14 OAI97182.1 - 0.12 12.1 4.5 0.26 11.0 3.1 1.7 1 1 0 1 1 1 0 SPX domain ESX-1_EspG PF14011.1 OAI97186.1 - 0.045 12.9 0.6 0.12 11.5 0.2 1.7 1 1 1 2 2 2 0 EspG family Phage_int_SAM_1 PF02899.12 OAI97187.1 - 0.038 14.1 0.0 7.4 6.8 0.0 2.7 1 1 2 3 3 3 0 Phage integrase, N-terminal SAM-like domain Aldedh PF00171.17 OAI97192.1 - 1.6e-10 39.9 0.0 1.6e-10 39.9 0.0 1.6 2 0 0 2 2 2 1 Aldehyde dehydrogenase family Pkinase PF00069.20 OAI97213.1 - 3.2e-24 85.4 0.0 5e-18 65.1 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAI97213.1 - 1.1e-10 41.0 0.0 5.7e-08 32.1 0.0 3.2 1 1 0 1 1 1 1 Protein tyrosine kinase FAM47 PF14642.1 OAI97220.1 - 3.2 6.9 15.0 0.29 10.3 3.4 2.0 1 1 1 2 2 2 0 FAM47 family CTD PF12815.2 OAI97222.1 - 6.5e-10 39.4 58.3 0.0001 22.7 6.1 4.7 1 1 3 4 4 4 4 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.24 OAI97222.1 - 0.00073 19.1 0.6 0.00073 19.1 0.4 2.3 3 0 0 3 3 3 1 KOW motif FAD_binding_8 PF08022.7 OAI97227.1 - 5.7e-19 67.9 0.0 1.1e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 OAI97227.1 - 8e-15 55.0 0.0 1.7e-13 50.7 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 OAI97227.1 - 2.4e-09 37.3 4.8 2.4e-09 37.3 3.3 1.9 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 OAI97227.1 - 0.00046 20.2 0.0 0.024 14.7 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Phage_integrase PF00589.17 OAI97231.1 - 5.8e-05 22.8 0.0 9.6e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 Phage integrase family FAD_binding_4 PF01565.18 OAI97236.1 - 4.2e-22 78.1 1.7 1.4e-21 76.4 0.9 1.9 2 0 0 2 2 2 1 FAD binding domain Nuc_N PF14448.1 OAI97238.1 - 0.12 11.9 0.0 4 7.0 0.0 2.5 2 0 0 2 2 2 0 Nuclease N terminal gag-asp_proteas PF13975.1 OAI97240.1 - 0.014 15.2 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 OAI97240.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease BRF1 PF07741.8 OAI97240.1 - 0.022 14.9 1.8 0.17 12.0 1.1 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain zf-CCHC PF00098.18 OAI97240.1 - 0.057 13.3 1.8 0.12 12.3 1.2 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 OAI97240.1 - 0.1 11.9 0.0 0.54 9.5 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_4 PF14392.1 OAI97240.1 - 0.3 10.7 1.8 0.91 9.2 1.2 1.8 1 0 0 1 1 1 0 Zinc knuckle CENP-B_dimeris PF09026.5 OAI97243.1 - 0.063 13.5 7.0 0.16 12.2 4.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 OAI97243.1 - 0.31 10.5 4.5 0.59 9.6 3.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 OAI97243.1 - 0.34 10.1 1.8 0.66 9.1 1.2 1.4 1 0 0 1 1 1 0 NOA36 protein PI3K_1B_p101 PF10486.4 OAI97243.1 - 1.5 6.3 2.8 2.1 5.8 1.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BSP_II PF05432.6 OAI97243.1 - 8.8 5.5 16.0 0.024 13.9 3.4 2.3 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) RNase_H2_suC PF08615.6 OAI97246.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) zf-CCHC PF00098.18 OAI97250.1 - 1.2e-05 25.0 3.8 2.2e-05 24.1 2.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Pkinase PF00069.20 OAI97254.1 - 1.4e-54 185.0 0.0 1.9e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI97254.1 - 9.8e-31 106.7 0.0 1.3e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI97254.1 - 9.4e-07 28.0 0.0 1.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAI97254.1 - 0.0022 17.0 0.0 0.0041 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAI97254.1 - 0.0025 17.5 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 OAI97254.1 - 0.043 12.5 0.1 0.062 12.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 OAI97254.1 - 0.086 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Helicase_C PF00271.26 OAI97259.1 - 1.6e-05 24.6 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAI97259.1 - 0.00032 20.2 0.0 0.005 16.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4193 PF13834.1 OAI97260.1 - 0.14 12.3 4.1 0.085 13.0 1.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) MCM PF00493.18 OAI97264.1 - 5.1e-32 110.9 0.0 5.6e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 OAI97264.1 - 0.016 14.4 0.1 0.021 14.0 0.0 1.4 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI MCM PF00493.18 OAI97265.1 - 2.3e-38 131.8 0.1 2.8e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 OAI97266.1 - 6.3e-13 49.2 0.0 9.6e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 MCM N-terminal domain Zeta_toxin PF06414.7 OAI97266.1 - 0.071 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DCX PF03607.12 OAI97266.1 - 0.11 12.0 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 Doublecortin FAD_binding_4 PF01565.18 OAI97268.1 - 5.4e-17 61.5 0.1 7.6e-17 61.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAI97269.1 - 0.00083 19.2 0.4 0.0019 18.0 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like DDE_3 PF13358.1 OAI97273.1 - 3.7e-14 52.7 0.0 8.7e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAI97273.1 - 5.1e-06 27.1 0.3 1.9e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 OAI97273.1 - 7.4e-06 26.0 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_21 PF13276.1 OAI97273.1 - 0.0065 16.4 0.4 0.013 15.4 0.3 1.4 1 0 0 1 1 1 1 HTH-like domain HTH_Tnp_Tc3_2 PF01498.13 OAI97273.1 - 0.0092 16.0 0.4 0.016 15.2 0.3 1.3 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.1 OAI97273.1 - 0.0093 15.4 1.0 0.023 14.2 0.4 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_IS630 PF01710.11 OAI97273.1 - 0.018 14.7 0.2 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 Transposase DUF1580 PF07618.6 OAI97273.1 - 0.095 12.0 0.4 0.29 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1580) UBX PF00789.15 OAI97274.1 - 1.6e-06 28.0 0.0 2.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 UBX domain CRAL_TRIO PF00650.15 OAI97290.1 - 6.1e-14 51.8 0.0 1.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAI97290.1 - 2.5e-13 49.9 1.0 5.1e-13 48.9 0.7 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 OAI97290.1 - 0.034 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 OAI97291.1 - 0.0084 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Pkinase PF00069.20 OAI97298.1 - 2.8e-33 115.1 0.0 4.6e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI97298.1 - 2.1e-11 43.3 0.0 3.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TP2 PF01254.13 OAI97304.1 - 0.015 15.6 5.2 0.028 14.7 3.6 1.4 1 0 0 1 1 1 0 Nuclear transition protein 2 DUF605 PF04652.11 OAI97304.1 - 0.51 9.6 6.7 0.62 9.4 4.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF837 PF05769.6 OAI97308.1 - 4.7e-06 26.2 7.7 0.0001 21.9 2.1 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF837) Nop14 PF04147.7 OAI97308.1 - 0.00052 18.1 28.2 0.00095 17.2 19.5 1.5 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 OAI97308.1 - 9.7 5.3 38.8 2.4 7.3 23.5 2.1 2 0 0 2 2 2 0 SDA1 Melittin PF01372.12 OAI97313.1 - 0.02 14.2 0.2 0.041 13.2 0.1 1.5 1 0 0 1 1 1 0 Melittin Thi4 PF01946.12 OAI97316.1 - 3e-15 55.9 0.1 1.5e-08 34.0 0.0 2.1 1 1 1 2 2 2 2 Thi4 family Homeobox PF00046.24 OAI97324.1 - 1.5e-23 82.1 1.4 1e-14 53.8 0.1 2.6 2 0 0 2 2 2 2 Homeobox domain Homeobox_KN PF05920.6 OAI97324.1 - 8.8e-06 25.3 0.8 0.0014 18.2 0.1 2.6 2 0 0 2 2 2 2 Homeobox KN domain SusE PF14292.1 OAI97324.1 - 0.0044 16.8 0.3 2.3 8.0 0.1 2.6 2 1 0 2 2 2 2 SusE outer membrane protein HTH_28 PF13518.1 OAI97324.1 - 0.0077 16.2 0.1 2.7 8.0 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain 2Fe-2S_thioredx PF01257.14 OAI97324.1 - 0.012 15.2 0.1 0.22 11.1 0.1 2.2 2 0 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin HTH_23 PF13384.1 OAI97324.1 - 0.025 14.2 0.2 14 5.5 0.0 3.0 3 0 0 3 3 3 0 Homeodomain-like domain Inhibitor_I53 PF11714.3 OAI97324.1 - 4.7 7.2 8.6 0.55 10.2 1.8 2.2 2 0 0 2 2 2 0 Thrombin inhibitor Madanin DSPc PF00782.15 OAI97328.1 - 8.2e-17 61.0 0.0 7.1e-16 58.0 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAI97328.1 - 0.036 13.3 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Pex14_N PF04695.8 OAI97328.1 - 0.23 11.4 2.1 0.82 9.7 1.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CTP_transf_1 PF01148.15 OAI97330.1 - 1.6e-11 44.3 7.7 5.5e-09 36.0 2.6 2.8 1 1 1 2 2 2 2 Cytidylyltransferase family Menin PF05053.8 OAI97330.1 - 5.7 4.9 10.2 8.4 4.4 7.1 1.2 1 0 0 1 1 1 0 Menin rve PF00665.21 OAI97346.1 - 2.7e-17 62.9 0.0 6.9e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain UBN2 PF14223.1 OAI97346.1 - 6.9e-07 29.0 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAI97346.1 - 3.2e-06 26.6 0.0 5.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAI97346.1 - 6.5 6.8 12.9 0.97 9.4 6.1 1.9 2 0 0 2 2 2 0 Zinc knuckle MULE PF10551.4 OAI97351.1 - 1.5e-18 66.7 0.1 1e-17 64.0 0.0 2.2 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 OAI97351.1 - 5.9e-08 31.6 0.0 8.5e-08 31.1 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Ribosomal_S13 PF00416.17 OAI97358.1 - 2.8e-24 85.6 0.0 3.6e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 OAI97358.1 - 0.0014 17.3 0.0 0.0017 16.9 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) FAM70 PF14967.1 OAI97358.1 - 3.4 6.7 5.3 4.5 6.3 3.7 1.1 1 0 0 1 1 1 0 FAM70 protein Herpes_capsid PF06112.6 OAI97358.1 - 3.6 7.6 7.7 2.4 8.1 2.7 2.0 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein UPF0203 PF05254.7 OAI97359.1 - 0.02 14.6 0.6 0.051 13.4 0.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 OAI97359.1 - 0.065 13.0 1.5 0.14 11.9 0.4 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 OAI97359.1 - 0.19 11.7 1.5 0.61 10.1 1.0 1.8 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.8 OAI97359.1 - 0.73 9.8 3.6 1.1 9.2 0.4 2.0 2 0 0 2 2 2 0 CHCH domain IPPT PF01715.12 OAI97362.1 - 9.1e-32 110.0 0.1 2.3e-27 95.6 0.1 3.2 2 1 0 2 2 2 2 IPP transferase Mito_carr PF00153.22 OAI97367.1 - 0.025 14.2 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial carrier protein AMMECR1 PF01871.12 OAI97370.1 - 8.3e-42 142.2 0.0 1.1e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 Cullin_binding PF03556.10 OAI97375.1 - 4.8e-31 107.3 0.0 8.2e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 OAI97375.1 - 1.6e-07 30.7 0.1 2.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Herpes_UL21 PF03252.8 OAI97375.1 - 0.051 12.0 1.0 0.055 11.9 0.2 1.3 2 0 0 2 2 2 0 Herpesvirus UL21 Peptidase_C48 PF02902.14 OAI97380.1 - 0.036 13.6 0.0 0.064 12.8 0.0 1.4 1 1 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain Cutinase PF01083.17 OAI97383.1 - 8.1e-24 84.3 0.0 1e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAI97383.1 - 2.1e-05 24.1 0.2 2.6e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAI97383.1 - 0.0014 18.3 0.3 0.0022 17.7 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAI97383.1 - 0.0047 16.8 1.0 0.027 14.3 0.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAI97383.1 - 1.1 9.1 3.3 6.2 6.7 0.7 2.5 2 0 0 2 2 2 0 Putative lysophospholipase zf-RING_UBOX PF13445.1 OAI97386.1 - 3.2e-16 58.7 0.3 7.2e-16 57.6 0.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 OAI97386.1 - 1.8e-11 43.9 0.0 3.7e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_5 PF14634.1 OAI97386.1 - 5.7e-05 22.7 0.7 0.00012 21.7 0.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 OAI97386.1 - 9.8e-05 22.1 0.7 0.00022 20.9 0.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAI97386.1 - 0.00015 21.6 1.1 0.0003 20.7 0.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAI97386.1 - 0.00024 20.9 0.4 0.00054 19.7 0.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 OAI97386.1 - 0.00027 20.5 0.6 0.00049 19.7 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 OAI97386.1 - 0.0025 17.0 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 OAI97386.1 - 0.0034 16.9 0.9 0.0072 15.9 0.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PilJ PF13675.1 OAI97386.1 - 0.086 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term CbiG_C PF01890.11 OAI97390.1 - 0.031 14.5 3.3 0.21 11.8 3.0 1.8 2 0 0 2 2 2 0 Cobalamin synthesis G C-terminus Phage_int_SAM_4 PF13495.1 OAI97390.1 - 0.15 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain RVT_3 PF13456.1 OAI97393.1 - 0.056 13.2 0.1 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like DDE_Tnp_1 PF01609.16 OAI97397.1 - 2.6e-16 59.8 0.1 4.5e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 Transposase DDE domain PepSY_TM_2 PF13703.1 OAI97397.1 - 0.11 12.7 0.3 0.24 11.5 0.2 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix DUF1178 PF06676.6 OAI97399.1 - 0.39 10.8 4.5 0.18 12.0 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) OrfB_Zn_ribbon PF07282.6 OAI97404.1 - 4.2e-13 48.7 0.1 8.8e-13 47.7 0.1 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.3 OAI97404.1 - 4.3e-09 35.5 0.3 1e-08 34.3 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_IS605 PF01385.14 OAI97404.1 - 1.1e-07 31.4 0.0 2.2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Probable transposase Peptidase_S10 PF00450.17 OAI97417.1 - 8.1e-28 97.7 0.0 4e-22 78.9 0.0 2.2 2 0 0 2 2 2 2 Serine carboxypeptidase Abhydrolase_6 PF12697.2 OAI97417.1 - 0.00095 19.1 4.1 0.0038 17.1 2.8 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family CW_binding_2 PF04122.7 OAI97417.1 - 0.096 12.9 0.2 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 G10 PF01125.12 OAI97420.1 - 6.7e-52 174.8 8.8 7.7e-52 174.7 6.1 1.0 1 0 0 1 1 1 1 G10 protein Syntaxin-6_N PF09177.6 OAI97421.1 - 5.9e-17 61.8 0.7 6.2e-16 58.5 0.0 2.2 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 OAI97421.1 - 9.7e-09 34.7 1.2 9.7e-09 34.7 0.8 2.3 2 0 0 2 2 2 1 SNARE domain FliJ PF02050.11 OAI97421.1 - 0.0007 19.6 2.5 0.019 15.0 0.3 2.6 2 1 1 3 3 3 1 Flagellar FliJ protein Use1 PF09753.4 OAI97421.1 - 0.0026 17.2 0.0 0.0046 16.4 0.0 1.5 2 0 0 2 2 2 1 Membrane fusion protein Use1 HisKA_3 PF07730.8 OAI97421.1 - 0.011 16.0 5.5 0.37 11.1 0.2 2.4 2 0 0 2 2 2 0 Histidine kinase DUF2046 PF09755.4 OAI97421.1 - 0.023 13.6 1.8 0.96 8.2 0.5 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF812 PF05667.6 OAI97421.1 - 0.099 11.1 1.1 5.5 5.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Sec34 PF04136.10 OAI97421.1 - 0.11 12.2 0.0 0.86 9.2 0.0 2.1 2 0 0 2 2 2 0 Sec34-like family GP41 PF00517.12 OAI97421.1 - 0.44 10.0 1.9 13 5.2 0.1 2.4 2 1 1 3 3 3 0 Retroviral envelope protein DUF848 PF05852.6 OAI97421.1 - 0.77 9.6 4.2 1.4 8.7 0.7 2.2 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) p450 PF00067.17 OAI97428.1 - 2.7e-13 49.2 0.0 3.7e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Spt5-NGN PF03439.8 OAI97431.1 - 5.7e-17 61.2 0.0 1.4e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 OAI97431.1 - 5.7e-10 39.6 12.0 5.7e-10 39.6 8.3 3.7 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 OAI97431.1 - 4.3e-06 26.2 10.6 4.1e-05 23.1 0.2 3.2 3 0 0 3 3 3 2 KOW motif Chordopox_G2 PF05796.7 OAI97431.1 - 0.083 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus protein G2 Ribosomal_L19 PF01245.15 OAI97431.1 - 0.72 9.6 3.9 10 5.9 1.1 2.6 1 1 1 2 2 2 0 Ribosomal protein L19 Ribosomal_L21e PF01157.13 OAI97431.1 - 0.88 9.4 5.3 3 7.6 0.8 3.1 2 1 1 3 3 3 0 Ribosomal protein L21e FAD_binding_1 PF00667.15 OAI97433.1 - 6.8e-30 104.1 0.0 1.1e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 OAI97433.1 - 1.1e-23 83.7 0.0 3.1e-23 82.3 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 OAI97433.1 - 6.4e-08 33.1 0.0 1.8e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 OAI97433.1 - 0.005 16.8 0.0 0.0089 16.0 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.2 OAI97433.1 - 0.098 12.0 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Flavodoxin domain PRA-PH PF01503.12 OAI97440.1 - 1.5e-11 44.3 0.4 3.3e-11 43.2 0.3 1.6 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 OAI97440.1 - 0.00036 20.4 0.1 0.00065 19.6 0.1 1.4 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Vps5 PF09325.5 OAI97447.1 - 2e-06 27.2 3.7 0.00055 19.2 0.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like FAM92 PF06730.6 OAI97447.1 - 0.0083 15.4 0.7 0.016 14.5 0.5 1.4 1 0 0 1 1 1 1 FAM92 protein BAR PF03114.13 OAI97447.1 - 0.07 12.6 0.9 0.93 8.9 0.0 2.1 2 0 0 2 2 2 0 BAR domain SMI1_KNR4 PF09346.5 OAI97455.1 - 4.1e-23 81.8 0.0 6.6e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Mitofilin PF09731.4 OAI97460.1 - 0.044 12.4 64.5 0.1 11.2 18.7 2.2 2 0 0 2 2 2 0 Mitochondrial inner membrane protein NPV_P10 PF05531.7 OAI97460.1 - 1.1 9.5 0.0 1.1 9.5 0.0 4.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.6 OAI97460.1 - 1.5 6.2 4.4 2.3 5.6 3.1 1.2 1 0 0 1 1 1 0 Prominin DUF1770 PF08589.5 OAI97468.1 - 0.23 12.1 6.1 0.11 13.0 2.0 2.1 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) Asp PF00026.18 OAI97479.1 - 1.1e-23 84.0 7.1 3.5e-23 82.3 4.9 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAI97479.1 - 2.3e-06 27.6 2.1 4e-05 23.6 1.5 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAI97479.1 - 0.0015 18.9 1.0 0.0066 16.9 0.3 2.0 2 0 0 2 2 2 1 Aspartyl protease DUF3370 PF11850.3 OAI97479.1 - 0.063 11.7 0.0 0.091 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3370) Asp PF00026.18 OAI97480.1 - 1.2e-33 116.7 0.1 1.5e-33 116.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 OAI97480.1 - 2.1e-05 24.1 0.0 7.3e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF3344 PF11824.3 OAI97480.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3344) Exo_endo_phos_2 PF14529.1 OAI97486.1 - 1.4e-14 53.7 0.6 4.4e-14 52.1 0.1 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAI97486.1 - 4.2e-07 30.1 0.0 6.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dimer_Tnp_hAT PF05699.9 OAI97494.1 - 1.1e-20 72.9 0.0 3.2e-20 71.5 0.0 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAI97494.1 - 0.052 13.5 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) PMT PF02366.13 OAI97502.1 - 5.8e-08 32.3 1.9 0.00051 19.4 0.1 2.1 1 1 1 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase RVT_2 PF07727.9 OAI97508.1 - 7.8e-19 67.6 0.0 1e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 OAI97508.1 - 0.021 14.5 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like RVT_2 PF07727.9 OAI97509.1 - 1.6e-29 102.6 0.1 2.2e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ELFV_dehydrog PF00208.16 OAI97524.1 - 4.2e-23 82.1 0.0 5.1e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RRM_5 PF13893.1 OAI97530.1 - 6e-09 35.6 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAI97530.1 - 9.3e-09 34.8 0.0 1.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAI97530.1 - 6.7e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 OAI97530.1 - 0.00012 21.6 1.9 0.0002 20.9 1.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.1 OAI97530.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Malectin_like PF12819.2 OAI97530.1 - 0.17 10.9 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate-binding protein of the ER Prenyltrans PF00432.16 OAI97531.1 - 2.4e-09 36.5 0.0 3.7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 OAI97531.1 - 0.034 14.5 0.0 0.038 14.3 0.0 1.1 1 0 0 1 1 1 0 Prenyltransferase-like FliD_N PF02465.13 OAI97536.1 - 0.31 11.4 3.5 0.46 10.8 2.4 1.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Rifin_STEVOR PF02009.11 OAI97544.1 - 0.052 13.1 0.6 0.11 12.1 0.4 1.4 1 1 0 1 1 1 0 Rifin/stevor family RVT_2 PF07727.9 OAI97548.1 - 2.9e-83 278.6 0.0 3.8e-83 278.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4316 PF14195.1 OAI97552.1 - 4.1 7.5 7.1 4.5e+02 1.0 4.9 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4316) RVT_1 PF00078.22 OAI97563.1 - 1.3e-23 83.4 0.0 2.3e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAI97563.1 - 0.0028 17.2 0.0 0.0059 16.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase CN_hydrolase PF00795.17 OAI97577.1 - 4.1e-19 68.6 0.0 1.6e-17 63.4 0.0 2.2 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase YlbD_coat PF14071.1 OAI97577.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative coat protein Med26 PF08711.6 OAI97588.1 - 1.3e-05 24.6 0.0 1.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Med3 PF11593.3 OAI97588.1 - 1.1 8.4 6.4 1.2 8.2 4.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ras PF00071.17 OAI97589.1 - 2.3e-50 170.1 0.2 3.2e-50 169.6 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAI97589.1 - 6.1e-15 55.7 0.0 1.1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAI97589.1 - 5.4e-11 42.0 0.0 1.8e-10 40.3 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 OAI97589.1 - 1.2e-05 25.2 0.0 2.6e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAI97589.1 - 0.00033 20.1 0.0 0.00099 18.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 OAI97589.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 OAI97589.1 - 0.0056 16.5 0.5 0.018 14.8 0.3 2.1 1 1 0 1 1 1 1 Dynamin family DUF89 PF01937.14 OAI97589.1 - 0.024 13.4 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF89 DDE_Tnp_4 PF13359.1 OAI97594.1 - 1.4e-07 31.2 0.0 1.9e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Proteasome PF00227.21 OAI97598.1 - 8.4e-23 80.6 0.0 1.2e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Mito_carr PF00153.22 OAI97608.1 - 9.7e-11 41.2 1.4 0.00027 20.5 0.0 4.1 4 0 0 4 4 4 2 Mitochondrial carrier protein PRA1 PF03208.14 OAI97608.1 - 0.4 10.0 3.2 15 4.8 0.0 2.6 2 0 0 2 2 2 0 PRA1 family protein Varsurf_PPLC PF03490.8 OAI97616.1 - 3.3e-05 23.4 0.0 8.1e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C PI-PLC-X PF00388.14 OAI97616.1 - 0.00012 21.5 0.0 0.00028 20.2 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain RVT_1 PF00078.22 OAI97620.1 - 7.1e-13 48.3 0.0 1.3e-12 47.5 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBN2_2 PF14227.1 OAI97641.1 - 4.2e-05 23.0 0.1 7.2e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAI97641.1 - 0.001 18.8 11.6 0.0048 16.7 0.8 2.9 2 1 0 2 2 2 2 Zinc knuckle PIN_4 PF13638.1 OAI97644.1 - 6e-21 74.9 0.0 3.6e-20 72.4 0.0 2.2 1 1 0 1 1 1 1 PIN domain DUF3696 PF12476.3 OAI97652.1 - 0.091 12.7 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) CobT PF06213.7 OAI97656.1 - 0.021 13.9 9.0 0.023 13.8 6.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nucleo_P87 PF07267.6 OAI97656.1 - 0.029 13.0 6.0 0.03 13.0 4.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2457 PF10446.4 OAI97656.1 - 0.032 12.9 10.9 0.034 12.8 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 OAI97656.1 - 0.1 12.0 5.8 0.11 11.9 4.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin FimP PF09766.4 OAI97656.1 - 0.16 11.0 5.0 0.18 10.8 3.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein Daxx PF03344.10 OAI97656.1 - 0.33 9.3 8.5 0.34 9.3 5.9 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 OAI97656.1 - 0.86 7.4 10.7 0.82 7.5 7.4 1.0 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.6 OAI97656.1 - 1.1 8.7 11.2 1.1 8.6 7.8 1.1 1 0 0 1 1 1 0 PPP4R2 Sigma70_ner PF04546.8 OAI97656.1 - 1.4 8.4 11.0 1.8 8.1 7.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 OAI97656.1 - 2.3 7.4 8.0 2.4 7.3 5.6 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 OAI97656.1 - 2.4 6.0 12.4 2.8 5.8 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 OAI97656.1 - 2.8 7.7 7.3 3.7 7.3 5.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF1510 PF07423.6 OAI97656.1 - 3.2 7.0 11.4 3.5 6.9 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sec62 PF03839.11 OAI97656.1 - 3.9 6.8 5.2 4.4 6.6 3.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3245 PF11595.3 OAI97656.1 - 5.8 7.1 14.0 8.1 6.6 9.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3245) TRAP_alpha PF03896.11 OAI97656.1 - 9.2 5.1 8.7 12 4.8 6.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit AAA PF00004.24 OAI97657.1 - 6.5e-26 91.0 0.0 7.5e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAI97657.1 - 1e-06 28.8 0.3 7e-06 26.1 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAI97657.1 - 1.6e-06 28.2 0.2 0.00033 20.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAI97657.1 - 1.2e-05 24.8 0.9 4.9e-05 22.8 0.7 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAI97657.1 - 6.4e-05 22.6 1.0 0.00036 20.2 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 OAI97657.1 - 8.5e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 OAI97657.1 - 0.00016 21.3 1.0 0.00089 18.8 0.7 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAI97657.1 - 0.0054 16.6 0.0 0.0064 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 OAI97657.1 - 0.0063 15.2 0.0 0.0067 15.1 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 OAI97657.1 - 0.0086 16.8 0.0 0.012 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAI97657.1 - 0.0092 15.4 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 OAI97657.1 - 0.0098 15.8 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 OAI97657.1 - 0.01 15.2 0.2 0.033 13.6 0.1 2.0 1 1 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 OAI97657.1 - 0.025 14.2 0.2 0.54 9.9 0.2 2.0 1 1 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 OAI97657.1 - 0.032 13.8 0.4 0.24 10.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 OAI97657.1 - 0.04 13.8 0.0 0.051 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 OAI97657.1 - 0.048 13.3 0.1 0.42 10.3 0.0 2.1 1 1 1 2 2 2 0 NTPase AAA_11 PF13086.1 OAI97657.1 - 0.048 13.2 0.0 0.055 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 OAI97657.1 - 0.064 12.4 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 OAI97657.1 - 0.065 13.5 0.0 0.092 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 OAI97657.1 - 0.084 11.7 0.0 0.089 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Miro PF08477.8 OAI97657.1 - 0.12 12.9 0.0 0.27 11.7 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein AAA_35 PF14516.1 OAI97657.1 - 0.14 10.7 0.0 0.44 9.1 0.0 1.6 1 1 1 2 2 2 0 AAA-like domain PhoH PF02562.11 OAI97657.1 - 0.17 11.1 0.4 0.61 9.2 0.1 1.7 1 1 1 2 2 2 0 PhoH-like protein MRP-L47 PF06984.8 OAI97661.1 - 4.5e-14 52.1 0.5 8.9e-14 51.1 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DASH_Spc19 PF08287.6 OAI97662.1 - 3.3e-10 39.7 5.4 5.6e-10 39.0 3.7 1.4 1 1 0 1 1 1 1 Spc19 WASH_WAHD PF11945.3 OAI97662.1 - 0.075 12.3 5.3 0.16 11.2 0.8 2.0 1 1 1 2 2 2 0 WAHD domain of WASH complex DUF3259 PF11652.3 OAI97662.1 - 0.13 12.4 1.3 4.9 7.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3259) IFT43 PF15305.1 OAI97662.1 - 0.24 11.4 3.8 0.31 11.0 2.6 1.4 1 1 0 1 1 1 0 Intraflagellar transport protein 43 Sipho_Gp157 PF05565.6 OAI97662.1 - 0.75 9.3 6.6 3.8 7.0 0.6 2.1 1 1 1 2 2 2 0 Siphovirus Gp157 GCN5L1 PF06320.8 OAI97662.1 - 0.77 9.6 6.7 0.35 10.7 0.1 2.0 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Myosin_tail_1 PF01576.14 OAI97662.1 - 0.82 7.3 13.2 0.097 10.3 0.8 2.0 2 0 0 2 2 2 0 Myosin tail DUF641 PF04859.7 OAI97662.1 - 0.87 9.3 7.2 0.71 9.6 2.1 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) K-box PF01486.12 OAI97662.1 - 0.95 9.2 5.4 2.3 8.0 3.0 2.1 1 1 0 1 1 1 0 K-box region TBPIP PF07106.8 OAI97662.1 - 1.5 8.3 5.0 1.4 8.4 0.3 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) OEP PF02321.13 OAI97662.1 - 2.3 7.7 12.4 2.4 7.7 2.6 2.2 2 0 0 2 2 2 0 Outer membrane efflux protein DUF4446 PF14584.1 OAI97662.1 - 3.2 7.5 4.9 5.6 6.7 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Prefoldin_2 PF01920.15 OAI97662.1 - 4.4 7.1 7.7 15 5.4 0.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit NTR2 PF15458.1 OAI97662.1 - 6.1 6.0 9.4 7.8 5.6 5.8 1.7 1 1 1 2 2 2 0 Nineteen complex-related protein 2 DUF4337 PF14235.1 OAI97662.1 - 9.9 5.9 12.9 3.6 7.4 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Y_phosphatase2 PF03162.8 OAI97666.1 - 2.4e-22 79.0 0.0 3.1e-13 49.4 0.0 2.5 3 0 0 3 3 3 2 Tyrosine phosphatase family Ribosomal_60s PF00428.14 OAI97666.1 - 1.7e-05 25.1 1.5 3.3e-05 24.2 1.0 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein NOA36 PF06524.7 OAI97666.1 - 0.63 9.2 6.4 1.1 8.4 4.4 1.3 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 OAI97666.1 - 2 7.9 16.6 4.6 6.7 11.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 OAI97666.1 - 2.9 7.4 14.8 0.52 9.9 6.8 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region BSP_II PF05432.6 OAI97666.1 - 5.7 6.1 18.9 3.5 6.8 10.4 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Sporozoite_P67 PF05642.6 OAI97666.1 - 6.5 4.4 7.8 0.49 8.1 1.0 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF2722 PF10846.3 OAI97666.1 - 6.8 5.6 8.5 10 5.0 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RXT2_N PF08595.6 OAI97666.1 - 9.1 6.0 10.1 9.3 6.0 5.8 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal rve PF00665.21 OAI97670.1 - 2e-15 56.9 0.0 4.8e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain p450 PF00067.17 OAI97674.1 - 7.6e-20 70.8 0.0 2.5e-19 69.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.19 OAI97679.1 - 1.1e-14 54.1 0.1 1.5e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAI97679.1 - 0.00019 21.5 0.0 0.00022 21.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAI97679.1 - 0.0004 20.0 0.0 0.00059 19.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 OAI97679.1 - 0.00079 19.5 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAI97679.1 - 0.0052 16.6 0.2 0.0083 15.9 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAI97679.1 - 0.032 14.1 0.0 0.037 13.9 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SspB PF04386.8 OAI97679.1 - 0.048 13.2 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Stringent starvation protein B PIF1 PF05970.9 OAI97683.1 - 0.0059 15.6 0.0 0.0085 15.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Torsin PF06309.6 OAI97683.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Torsin rve PF00665.21 OAI97692.1 - 1.7e-14 53.9 0.0 6.3e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 OAI97692.1 - 0.0014 18.0 0.0 0.02 14.4 0.0 2.7 3 0 0 3 3 3 1 Integrase core domain DUF2268 PF10026.4 OAI97692.1 - 0.015 14.7 0.7 0.029 13.7 0.5 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Myb_DNA-bind_4 PF13837.1 OAI97695.1 - 0.018 15.1 0.0 0.042 13.9 0.0 1.7 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain His_Phos_1 PF00300.17 OAI97700.1 - 0.028 14.4 0.1 0.053 13.6 0.1 1.7 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Sterol_MT_C PF08498.5 OAI97701.1 - 4.2e-28 97.0 0.1 5.5e-28 96.7 0.0 1.2 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal HRM PF02793.17 OAI97701.1 - 0.0084 16.1 1.0 0.013 15.4 0.7 1.2 1 0 0 1 1 1 1 Hormone receptor domain RRM_6 PF14259.1 OAI97708.1 - 8.9e-06 25.5 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAI97708.1 - 0.0087 15.6 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L29 PF00831.18 OAI97709.1 - 5.1e-19 67.6 3.9 5.1e-19 67.6 2.7 2.0 2 0 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 OAI97709.1 - 0.013 15.7 0.5 0.016 15.4 0.4 1.3 1 0 0 1 1 1 0 Ribosomal protein S9/S16 DUF607 PF04678.8 OAI97709.1 - 1.4 8.7 4.5 3.4 7.5 3.2 1.5 1 1 1 2 2 2 0 Protein of unknown function, DUF607 SurE PF01975.12 OAI97718.1 - 7.4e-40 136.3 0.0 1.3e-39 135.5 0.0 1.4 1 0 0 1 1 1 1 Survival protein SurE ATE_C PF04377.10 OAI97723.1 - 3.7e-30 104.6 0.1 5.4e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus Glyco_transf_8 PF01501.15 OAI97724.1 - 1.9e-24 86.3 0.0 3.1e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 OAI97724.1 - 0.0013 18.1 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative p450 PF00067.17 OAI97730.1 - 6.7e-60 202.9 0.6 1.3e-49 169.0 0.4 3.8 1 1 1 2 2 2 2 Cytochrome P450 TM_helix PF05552.7 OAI97730.1 - 2 8.1 6.4 4.1 7.1 4.4 1.5 1 0 0 1 1 1 0 Conserved TM helix MLANA PF14991.1 OAI97734.1 - 0.04 13.9 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A Complex1_49kDa PF00346.14 OAI97755.1 - 0.15 11.0 0.0 1.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit SBP_bac_7 PF03480.8 OAI97755.1 - 0.3 10.1 5.1 0.52 9.3 3.6 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 zf-CCHC_5 PF14787.1 OAI97755.1 - 1 8.8 8.2 4.9 6.7 3.6 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Tom37_C PF11801.3 OAI97755.1 - 3.1 7.6 7.0 4.8 7.0 4.9 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain FUSC PF04632.7 OAI97755.1 - 6.3 5.0 6.4 9 4.5 4.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TPR_12 PF13424.1 OAI97760.1 - 2.4e-10 40.1 12.2 0.0004 20.2 0.4 4.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 OAI97760.1 - 8.7e-06 25.5 14.8 0.013 15.4 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAI97760.1 - 0.0029 17.3 10.8 11 6.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat SLT_2 PF13406.1 OAI97760.1 - 0.12 11.2 3.2 0.32 9.8 0.0 2.7 4 0 0 4 4 4 0 Transglycosylase SLT domain TPR_6 PF13174.1 OAI97760.1 - 2.1 8.9 5.4 24 5.6 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.20 OAI97765.1 - 8.7e-24 84.0 0.2 1.2e-23 83.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI97765.1 - 2.6e-14 52.9 0.2 3.4e-14 52.5 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 OAI97765.1 - 0.0073 15.1 0.0 0.009 14.8 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Myc_N PF01056.13 OAI97765.1 - 0.41 9.7 8.1 0.3 10.2 4.8 1.4 1 1 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 OAI97765.1 - 1 8.8 8.1 2 7.9 5.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin gag_pre-integrs PF13976.1 OAI97773.1 - 2.5e-06 27.0 0.0 7.9e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain UBN2 PF14223.1 OAI97773.1 - 0.00081 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RVP PF00077.15 OAI97773.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF2348 PF09807.4 OAI97796.1 - 0.00022 20.4 0.0 0.0004 19.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) NACHT PF05729.7 OAI97796.1 - 0.006 16.2 0.1 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Telomere_Sde2 PF13019.1 OAI97801.1 - 0.012 15.3 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 Telomere stability and silencing Sua5_yciO_yrdC PF01300.13 OAI97809.1 - 1.9e-47 160.8 0.0 7e-46 155.7 0.0 2.5 1 1 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 OAI97809.1 - 3e-24 85.4 0.0 9.6e-23 80.6 0.0 2.5 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding Glyco_hydro_92 PF07971.7 OAI97813.1 - 2.2e-38 132.1 0.0 2.6e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 VWA PF00092.23 OAI97814.1 - 0.00039 20.1 0.1 0.00045 19.9 0.1 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain Zip PF02535.17 OAI97818.1 - 0.28 10.1 4.2 0.44 9.5 2.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter UPF0560 PF10577.4 OAI97818.1 - 3.1 5.9 11.1 5.1 5.2 7.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Serglycin PF04360.7 OAI97818.1 - 5.3 6.7 18.1 3.9 7.1 1.9 2.8 2 0 0 2 2 2 0 Serglycin MerR-DNA-bind PF09278.6 OAI97819.1 - 0.12 12.7 0.6 0.19 12.1 0.4 1.2 1 0 0 1 1 1 0 MerR, DNA binding Asp_protease_2 PF13650.1 OAI97821.1 - 6.4e-05 23.3 0.0 0.00014 22.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI97821.1 - 0.0013 18.6 0.0 0.0047 16.8 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI97821.1 - 0.018 14.8 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Phage_integrase PF00589.17 OAI97835.1 - 0.0003 20.5 0.0 0.00034 20.3 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family TMEM171 PF15471.1 OAI97836.1 - 0.34 9.6 1.5 0.63 8.7 1.0 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 TPR_12 PF13424.1 OAI97839.1 - 2.1e-17 62.8 26.2 3.9e-06 26.7 0.2 6.2 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 OAI97839.1 - 1.5e-12 46.9 22.2 0.00094 19.0 0.2 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 OAI97839.1 - 0.00013 21.5 15.8 1.5 8.5 0.3 6.1 5 3 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 OAI97839.1 - 0.00017 21.2 17.1 15 5.7 0.0 7.6 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAI97839.1 - 0.00035 20.9 19.8 22 6.0 0.0 7.8 5 2 2 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAI97839.1 - 0.0028 17.3 1.0 1.1 9.1 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat T2SF PF00482.18 OAI97839.1 - 0.056 13.3 8.6 4.8 7.1 0.8 4.1 1 1 3 4 4 4 0 Type II secretion system (T2SS), protein F TPR_4 PF07721.9 OAI97839.1 - 0.4 11.2 12.7 9.5 6.9 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc5 PF12862.2 OAI97839.1 - 0.53 10.1 11.5 2 8.3 0.4 5.4 2 2 3 5 5 5 0 Anaphase-promoting complex subunit 5 SPOR PF05036.8 OAI97839.1 - 1.3 9.1 4.7 0.82 9.8 0.2 2.9 3 0 0 3 3 3 0 Sporulation related domain Myb_DNA-bind_4 PF13837.1 OAI97845.1 - 6.9e-05 22.8 0.2 0.00023 21.2 0.1 2.0 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF362 PF04015.7 OAI97845.1 - 0.14 11.5 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF362) Cytochrom_NNT PF03264.9 OAI97845.1 - 1.4 8.3 6.3 6.6 6.1 1.0 2.2 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region rve PF00665.21 OAI97853.1 - 1.2e-14 54.4 0.0 3.7e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAI97853.1 - 4.1e-12 45.9 0.0 7.8e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MSA-2c PF12238.3 OAI97857.1 - 0.16 11.6 5.8 0.28 10.8 3.9 1.5 1 1 0 1 1 1 0 Merozoite surface antigen 2c DUF755 PF05501.6 OAI97858.1 - 3.6 7.6 29.0 6.6 6.8 20.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TLP-20 PF06088.6 OAI97862.1 - 0.054 13.1 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAD_binding_2 PF00890.19 OAI97870.1 - 4.6e-60 203.6 4.1 3.8e-48 164.3 0.1 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAI97870.1 - 6.5e-23 81.2 8.2 3.9e-13 49.0 0.8 3.0 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAI97870.1 - 1.3e-21 76.3 7.1 5.1e-10 39.2 0.2 3.4 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 OAI97870.1 - 1.1e-14 54.4 3.8 4.3e-07 29.3 0.5 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAI97870.1 - 2.9e-14 53.4 3.7 1.2e-07 31.8 0.3 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAI97870.1 - 2.8e-13 49.1 0.7 2.7e-05 22.8 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.14 OAI97870.1 - 6.4e-13 48.4 2.0 5.3e-06 25.7 0.5 2.5 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 OAI97870.1 - 8.8e-12 45.5 1.3 6.2e-05 23.1 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAI97870.1 - 1.1e-10 40.9 4.2 0.0011 17.9 0.2 3.1 3 0 0 3 3 3 3 Glucose inhibited division protein A Amino_oxidase PF01593.19 OAI97870.1 - 9.2e-10 38.1 0.1 0.0014 17.8 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 OAI97870.1 - 3e-09 36.3 3.3 0.00033 19.8 0.2 2.6 3 0 0 3 3 3 2 Thi4 family Pyr_redox PF00070.22 OAI97870.1 - 8.5e-09 35.7 2.3 0.0025 18.1 0.1 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAI97870.1 - 5.7e-08 32.6 0.6 0.084 12.6 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 OAI97870.1 - 1.1e-06 27.8 0.3 0.018 13.9 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 OAI97870.1 - 1.5e-06 27.8 0.2 0.02 14.4 0.0 2.5 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 OAI97870.1 - 1.7e-06 28.2 0.1 0.024 14.9 0.0 2.6 3 0 0 3 3 2 2 Putative NAD(P)-binding GDI PF00996.13 OAI97870.1 - 2e-06 26.4 0.2 0.016 13.5 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor TrkA_N PF02254.13 OAI97870.1 - 3.2e-05 23.9 0.5 0.21 11.5 0.0 2.7 3 0 0 3 3 3 2 TrkA-N domain 3HCDH_N PF02737.13 OAI97870.1 - 0.00013 21.6 0.3 0.13 11.8 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 OAI97870.1 - 0.0036 17.2 0.6 1.5 8.7 0.0 2.6 3 0 0 3 3 2 1 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.9 OAI97870.1 - 0.0048 16.3 0.7 0.92 8.8 0.1 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 OAI97870.1 - 0.054 12.1 0.4 1.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase KR PF08659.5 OAI97870.1 - 0.07 12.7 0.1 7.1 6.2 0.0 2.3 2 0 0 2 2 2 0 KR domain YjeF_N PF03853.10 OAI97870.1 - 0.087 12.4 0.1 11 5.5 0.0 2.3 2 0 0 2 2 2 0 YjeF-related protein N-terminus PcrB PF01884.12 OAI97870.1 - 0.11 11.7 0.1 5.5 6.1 0.0 2.2 2 0 0 2 2 2 0 PcrB family DUF4341 PF14241.1 OAI97870.1 - 0.24 11.1 2.5 15 5.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4341) Shikimate_DH PF01488.15 OAI97870.1 - 0.28 11.3 0.9 33 4.5 0.1 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase RVT_1 PF00078.22 OAI97874.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97877.1 - 3e-16 59.6 0.0 4.8e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain CDC45 PF02724.9 OAI97880.1 - 0.28 9.1 7.3 0.35 8.8 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 OAI97880.1 - 0.45 8.9 11.1 0.53 8.7 7.7 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 OAI97880.1 - 7 5.2 25.9 10 4.6 17.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Complex1_LYR_1 PF13232.1 OAI97881.1 - 1.6e-09 37.8 4.1 2.5e-09 37.1 2.8 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 OAI97881.1 - 5.1e-09 35.8 5.5 9.7e-09 34.8 3.8 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 OAI97881.1 - 0.026 15.0 0.6 0.041 14.3 0.4 1.3 1 0 0 1 1 1 0 Complex1_LYR-like DUF1768 PF08719.6 OAI97890.1 - 8.2e-19 67.8 0.1 9.2e-19 67.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Sec61_beta PF03911.11 OAI97894.1 - 8.1e-17 60.7 0.3 1e-16 60.3 0.2 1.1 1 0 0 1 1 1 1 Sec61beta family NDUFB10 PF10249.4 OAI97896.1 - 0.0094 16.0 0.4 0.011 15.9 0.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HAD_2 PF13419.1 OAI97896.1 - 0.012 15.8 0.1 0.013 15.6 0.1 1.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF605 PF04652.11 OAI97902.1 - 0.011 15.1 38.2 0.0046 16.4 10.2 2.1 2 0 0 2 2 2 0 Vta1 like DUF2201_N PF13203.1 OAI97902.1 - 2.2 7.3 15.7 5.4 6.1 10.9 1.7 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2890 PF11081.3 OAI97905.1 - 0.034 14.1 16.3 0.064 13.3 7.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) SOBP PF15279.1 OAI97905.1 - 0.076 13.3 7.3 0.11 12.8 5.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Nucleoplasmin PF03066.10 OAI97905.1 - 0.24 10.8 12.6 0.46 10.0 6.3 2.2 2 0 0 2 2 2 0 Nucleoplasmin Sigma70_ner PF04546.8 OAI97905.1 - 0.76 9.3 13.5 0.096 12.2 4.5 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region eIF3_subunit PF08597.5 OAI97905.1 - 0.81 9.2 11.8 0.19 11.2 3.3 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Med3 PF11593.3 OAI97905.1 - 1.2 8.3 21.5 1.7 7.7 14.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal YL1 PF05764.8 OAI97905.1 - 1.7 8.1 18.2 0.069 12.7 5.8 2.1 1 1 1 2 2 2 0 YL1 nuclear protein RAP1 PF07218.6 OAI97905.1 - 3 5.8 10.0 4.2 5.3 6.9 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PRP21_like_P PF12230.3 OAI97905.1 - 3.2 7.1 11.2 0.2 11.1 2.4 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Plasmodium_Vir PF05795.6 OAI97905.1 - 6.6 5.8 5.4 9.9 5.2 3.7 1.3 1 1 0 1 1 1 0 Plasmodium vivax Vir protein PBP1_TM PF14812.1 OAI97905.1 - 7.2 6.9 24.2 0.071 13.4 5.3 2.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CM_2 PF01817.16 OAI97906.1 - 5.3e-07 29.6 0.0 0.00011 22.1 0.0 3.0 2 1 0 2 2 2 2 Chorismate mutase type II MULE PF10551.4 OAI97918.1 - 5.3e-19 68.1 0.0 1.4e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAI97918.1 - 3e-10 39.2 0.1 5.1e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 Transposase, Mutator family SWIM PF04434.12 OAI97918.1 - 2.3e-07 30.1 0.1 6.6e-07 28.6 0.1 1.8 1 0 0 1 1 1 1 SWIM zinc finger DDE_Tnp_ISL3 PF01610.12 OAI97918.1 - 0.087 12.3 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Transposase Pantoate_transf PF02548.10 OAI97934.1 - 3.9e-87 291.6 0.5 3.9e-82 275.2 0.1 2.3 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 OAI97934.1 - 0.014 14.6 0.1 0.014 14.6 0.0 2.5 3 0 0 3 3 3 0 Phosphoenolpyruvate phosphomutase ORC6 PF05460.8 OAI97935.1 - 0.21 10.6 4.8 0.071 12.1 1.2 1.8 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) RRM_1 PF00076.17 OAI97944.1 - 1.9e-79 261.2 2.0 5.2e-19 67.6 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAI97944.1 - 1.5e-53 178.6 5.0 1.1e-15 57.3 0.0 4.5 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAI97944.1 - 4.2e-42 141.7 5.4 2.3e-12 46.5 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 OAI97944.1 - 5.7e-29 99.5 0.5 7.2e-28 96.0 0.3 2.9 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 OAI97944.1 - 8.1e-07 28.7 0.5 0.87 9.4 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 OAI97944.1 - 0.016 15.4 3.9 4.2 7.6 0.0 4.1 4 0 0 4 4 4 0 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 OAI97944.1 - 0.017 14.8 3.4 4.3 7.1 0.1 3.8 4 0 0 4 4 4 0 Limkain b1 YL1 PF05764.8 OAI97954.1 - 0.11 12.1 13.6 0.15 11.6 9.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein TFIIF_alpha PF05793.7 OAI97954.1 - 0.21 9.8 20.3 0.29 9.4 14.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNase_H2-Ydr279 PF09468.5 OAI97954.1 - 1.7 7.7 13.0 0.37 9.9 4.6 2.0 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Abhydrolase_6 PF12697.2 OAI97963.1 - 3.7e-08 33.5 1.4 1.1e-07 31.9 1.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAI97963.1 - 2.4e-07 30.6 0.1 4.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family RVT_1 PF00078.22 OAI97966.1 - 7.1e-16 58.2 0.0 1.4e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSP70 PF00012.15 OAI97970.1 - 1.1e-17 63.2 0.0 5.3e-17 60.9 0.0 1.8 1 1 0 1 1 1 1 Hsp70 protein WD40 PF00400.27 OAI97974.1 - 2.9e-23 80.8 5.4 1.4e-07 31.0 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat IKI3 PF04762.7 OAI97974.1 - 0.00034 18.5 0.9 0.045 11.5 0.3 2.1 2 0 0 2 2 2 2 IKI3 family eIF2A PF08662.6 OAI97974.1 - 0.0031 17.2 0.4 0.11 12.2 0.3 2.9 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Tubulin PF00091.20 OAI97985.1 - 1.5e-63 214.5 0.0 3.1e-63 213.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 OAI97985.1 - 1.1e-40 138.6 0.0 1.6e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 OAI97985.1 - 0.00022 21.2 0.0 0.00074 19.5 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 OAI97985.1 - 0.002 17.6 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain ART PF01129.13 OAI97985.1 - 0.1 11.6 0.1 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase Tubulin_2 PF13809.1 OAI97985.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Ribonuclease_3 PF00636.21 OAI97998.1 - 3.8e-15 56.3 2.9 5.6e-15 55.7 0.0 2.7 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 OAI97998.1 - 0.00013 21.9 0.0 0.017 15.0 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease-III-like RVT_1 PF00078.22 OAI98007.1 - 2.3e-13 50.0 0.1 3.8e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAI98007.1 - 0.00013 22.4 0.1 0.00029 21.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI98007.1 - 0.0058 16.5 0.0 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI98007.1 - 0.0081 15.9 0.1 0.023 14.5 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF4218 PF13960.1 OAI98014.1 - 0.00027 20.3 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Pkinase PF00069.20 OAI98023.1 - 9.2e-43 146.2 0.0 2.1e-42 145.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI98023.1 - 1.1e-23 83.7 0.0 3.1e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Tropomyosin PF00261.15 OAI98023.1 - 0.00012 21.2 13.5 0.00012 21.2 9.3 4.1 1 1 3 4 4 4 2 Tropomyosin Kinase-like PF14531.1 OAI98023.1 - 0.002 17.1 0.2 0.0052 15.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like AAA_27 PF13514.1 OAI98023.1 - 0.012 13.3 50.8 0.017 12.8 35.2 1.2 1 0 0 1 1 1 0 AAA domain DUF3504 PF12012.3 OAI98023.1 - 0.074 12.8 5.2 0.035 13.8 1.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3504) APH PF01636.18 OAI98023.1 - 0.26 11.0 0.1 0.26 11.0 0.0 3.6 2 2 1 3 3 2 0 Phosphotransferase enzyme family Tropomyosin_1 PF12718.2 OAI98023.1 - 0.32 10.8 57.6 0.014 15.2 15.4 4.1 1 1 4 5 5 5 0 Tropomyosin like ERM PF00769.14 OAI98023.1 - 2.1 7.7 57.1 0.026 14.0 19.9 2.6 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 OAI98023.1 - 3.1 6.8 18.0 0.056 12.6 1.1 3.0 1 1 1 3 3 3 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 OAI98023.1 - 9.9 6.1 11.0 1.1 9.1 0.4 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Got1 PF04178.7 OAI98027.1 - 2.2e-20 72.8 13.5 2.5e-20 72.7 9.3 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family Thioredoxin PF00085.15 OAI98028.1 - 7.5e-31 105.8 0.0 9.2e-31 105.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 OAI98028.1 - 1.1e-08 35.1 0.2 9.5e-08 32.2 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAI98028.1 - 3.3e-08 33.5 0.0 1.3e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 OAI98028.1 - 2.5e-07 30.3 0.0 3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 OAI98028.1 - 3.6e-06 26.5 0.0 5.7e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAI98028.1 - 5.3e-05 22.8 0.0 6.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 OAI98028.1 - 0.00055 19.9 0.0 0.00078 19.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 OAI98028.1 - 0.0023 17.4 0.0 0.003 17.0 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF2847 PF11009.3 OAI98028.1 - 0.0044 16.6 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Glutaredoxin PF00462.19 OAI98028.1 - 0.0099 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_4 PF13462.1 OAI98028.1 - 0.02 14.9 0.0 2.4 8.1 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin DIM1 PF02966.11 OAI98028.1 - 0.023 14.2 0.0 0.025 14.1 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_3 PF13192.1 OAI98028.1 - 0.024 14.4 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain adh_short PF00106.20 OAI98041.1 - 6.7e-08 32.6 0.2 2.5e-07 30.7 0.1 2.0 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAI98041.1 - 0.00069 19.4 0.0 0.0012 18.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAI98041.1 - 0.0031 17.5 0.0 0.0039 17.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 OAI98041.1 - 0.014 14.5 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.20 OAI98042.1 - 1.2e-09 38.2 1.6 3.4e-09 36.8 0.1 2.4 3 2 0 3 3 3 1 short chain dehydrogenase Epimerase PF01370.16 OAI98042.1 - 5.2e-07 29.3 0.0 7.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 OAI98042.1 - 1.9e-06 27.8 0.0 7.6e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAI98042.1 - 2.4e-06 27.6 0.0 8.4e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 OAI98042.1 - 0.014 15.1 0.0 0.087 12.6 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 OAI98042.1 - 0.029 14.0 0.1 3.2 7.3 0.1 3.0 1 1 0 2 2 2 0 KR domain HHH_5 PF14520.1 OAI98042.1 - 0.09 12.9 0.1 0.3 11.2 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain PALP PF00291.20 OAI98046.1 - 6.9e-60 202.8 1.4 1.4e-59 201.8 1.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 OAI98046.1 - 7.7e-08 31.8 0.0 0.0001 21.8 0.0 3.0 3 0 0 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase mit_SMPDase PF14724.1 OAI98058.1 - 0.2 9.4 1.8 0.28 8.9 1.2 1.1 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase GMC_oxred_N PF00732.14 OAI98062.1 - 1.2e-30 106.7 0.0 2e-30 105.9 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAI98062.1 - 4.6e-05 22.4 1.1 0.00053 19.0 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAI98062.1 - 6.2e-05 22.9 0.0 0.00019 21.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAI98062.1 - 0.00063 18.6 0.5 0.001 18.0 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 OAI98062.1 - 0.0019 17.1 0.1 0.0028 16.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAI98062.1 - 0.049 13.6 0.1 0.097 12.7 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAI98062.1 - 0.15 11.1 0.1 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DDE_1 PF03184.14 OAI98068.1 - 8.6e-32 110.0 0.0 1.3e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAI98068.1 - 1.1e-08 34.7 0.0 6.1e-08 32.3 0.0 2.2 1 1 1 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 OAI98068.1 - 0.032 13.7 0.2 0.086 12.4 0.0 1.8 2 0 0 2 2 2 0 helix-turn-helix, Psq domain RVT_1 PF00078.22 OAI98083.1 - 0.0085 15.4 0.0 0.025 13.9 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 OAI98083.1 - 0.04 13.6 0.2 0.27 11.0 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase-like Mito_carr PF00153.22 OAI98101.1 - 2e-64 213.2 0.1 4.8e-20 71.0 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Lipase_GDSL PF00657.17 OAI98106.1 - 4.1e-06 26.7 0.0 7.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DCR PF14047.1 OAI98106.1 - 0.089 13.0 0.1 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Dppa2/4 conserved region MFS_1 PF07690.11 OAI98107.1 - 0.0046 15.7 1.8 0.0059 15.3 1.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.1 OAI98107.1 - 0.037 13.4 2.9 0.27 10.6 2.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF998 PF06197.8 OAI98107.1 - 4.2 6.6 9.3 5.2 6.3 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DNA_pol_viral_C PF00336.13 OAI98113.1 - 0.006 15.8 0.1 0.013 14.7 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain Phage_integrase PF00589.17 OAI98114.1 - 6.7e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 OAI98120.1 - 2.8e-13 49.7 0.0 6e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 OAI98120.1 - 0.0064 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAI98120.1 - 0.059 13.8 0.0 0.36 11.3 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease rve PF00665.21 OAI98130.1 - 7e-14 51.9 0.0 1.5e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAI98130.1 - 1.6e-06 27.6 0.0 3.6e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.17 OAI98146.1 - 3.9e-32 111.3 0.0 4.5e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Yae1_N PF09811.4 OAI98151.1 - 1.6e-05 24.2 8.9 2.7e-05 23.5 6.2 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Myticin-prepro PF10690.4 OAI98162.1 - 0.33 11.0 4.2 0.25 11.4 1.7 1.7 1 1 1 2 2 2 0 Myticin pre-proprotein from the mussel NOA36 PF06524.7 OAI98162.1 - 0.48 9.6 20.7 0.62 9.2 14.4 1.3 1 0 0 1 1 1 0 NOA36 protein FYDLN_acid PF09538.5 OAI98162.1 - 0.85 10.2 32.5 1.1 9.8 22.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CDC45 PF02724.9 OAI98162.1 - 1.4 6.8 26.0 1.5 6.7 18.0 1.0 1 0 0 1 1 1 0 CDC45-like protein U79_P34 PF03064.11 OAI98162.1 - 2.3 7.6 13.4 2.7 7.4 9.3 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1510 PF07423.6 OAI98162.1 - 3.1 7.1 23.9 3.4 6.9 16.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CENP-T PF15511.1 OAI98162.1 - 4.1 6.5 22.3 4.8 6.3 15.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T FLO_LFY PF01698.11 OAI98162.1 - 5.4 5.7 9.2 5.9 5.6 6.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein PPP4R2 PF09184.6 OAI98162.1 - 5.5 6.4 27.8 6.2 6.2 19.3 1.1 1 0 0 1 1 1 0 PPP4R2 DUF2151 PF10221.4 OAI98162.1 - 7.6 4.5 9.7 7.8 4.5 6.7 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Vfa1 PF08432.5 OAI98162.1 - 7.9 6.4 17.0 10 6.0 11.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Peptidase_M16 PF00675.15 OAI98174.1 - 8.2e-40 135.9 0.0 1.6e-39 135.0 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 OAI98174.1 - 3e-38 131.3 0.0 8.4e-38 129.8 0.0 1.8 1 1 0 1 1 1 1 Peptidase M16 inactive domain Iso_dh PF00180.15 OAI98182.1 - 5e-91 305.2 0.0 1.2e-90 303.9 0.0 1.5 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Synaptobrevin PF00957.16 OAI98183.1 - 1e-26 92.3 0.2 1.4e-26 91.8 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 OAI98183.1 - 2.3e-19 68.7 0.0 3.3e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain Actin PF00022.14 OAI98187.1 - 3.7e-76 256.0 0.0 4.5e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Actin AAA PF00004.24 OAI98190.1 - 2.2e-06 27.9 0.0 2.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 OAI98190.1 - 0.0003 20.4 1.1 0.00043 19.9 0.7 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 OAI98190.1 - 0.00042 20.0 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 OAI98190.1 - 0.00072 19.0 0.0 0.00087 18.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAI98190.1 - 0.00076 19.6 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAI98190.1 - 0.0031 17.5 0.0 0.0032 17.4 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 OAI98190.1 - 0.0043 17.8 0.0 0.0062 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAI98190.1 - 0.0074 16.1 0.0 0.0092 15.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAI98190.1 - 0.0078 15.6 0.0 0.0089 15.4 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 OAI98190.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 OAI98190.1 - 0.038 13.5 0.1 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 OAI98190.1 - 0.042 13.4 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 OAI98190.1 - 0.059 12.9 0.0 0.078 12.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.4 OAI98190.1 - 0.067 12.1 0.1 0.08 11.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.7 OAI98190.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Trypan_PARP PF05887.6 OAI98190.1 - 0.16 11.7 6.1 0.22 11.3 4.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RNA_helicase PF00910.17 OAI98190.1 - 0.16 12.1 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA helicase Neisseria_TspB PF05616.8 OAI98190.1 - 4 5.6 8.2 4.6 5.4 5.7 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein EXS PF03124.9 OAI98197.1 - 3.2e-58 197.4 1.8 1.5e-52 178.7 1.9 2.2 2 0 0 2 2 2 2 EXS family Homeobox PF00046.24 OAI98210.1 - 2.5e-14 52.6 0.5 6.6e-14 51.2 0.4 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 OAI98210.1 - 0.0025 17.4 0.7 0.0069 16.0 0.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Peptidase_C8 PF03569.8 OAI98210.1 - 0.071 12.4 0.2 0.11 11.7 0.2 1.3 1 0 0 1 1 1 0 Peptidase family C8 Sigma70_ner PF04546.8 OAI98210.1 - 0.1 12.2 4.7 0.25 10.9 3.2 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region WD40 PF00400.27 OAI98216.1 - 1.1e-29 101.1 4.9 8.2e-11 41.3 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 OAI98216.1 - 0.09 12.2 0.0 0.53 9.8 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain CCDC-167 PF15188.1 OAI98230.1 - 0.073 13.0 0.1 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Retrotrans_gag PF03732.12 OAI98231.1 - 0.00057 19.9 0.5 0.00082 19.4 0.4 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein DUF3366 PF11846.3 OAI98234.1 - 0.011 15.6 0.1 0.011 15.6 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3366) DUF3566 PF12089.3 OAI98234.1 - 1.2 9.1 8.3 0.89 9.5 0.1 2.9 3 0 0 3 3 3 0 Transmembrane domain of unknown function (DUF3566) PQ-loop PF04193.9 OAI98235.1 - 0.0055 16.2 0.4 0.012 15.1 0.0 1.8 2 0 0 2 2 2 1 PQ loop repeat DUF3515 PF12028.3 OAI98235.1 - 0.1 11.8 0.2 0.16 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) 60KD_IMP PF02096.15 OAI98239.1 - 2.2e-39 135.1 0.5 3.6e-39 134.4 0.4 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Peptidase_S10 PF00450.17 OAI98243.1 - 1.2e-98 331.0 0.0 1.5e-98 330.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Collagen PF01391.13 OAI98252.1 - 0.00018 20.9 22.1 0.00018 20.9 15.3 3.8 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) HTH_Mga PF08280.6 OAI98256.1 - 0.055 13.2 0.2 0.094 12.4 0.2 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain RVT_1 PF00078.22 OAI98269.1 - 1.3e-25 90.0 0.0 7.6e-25 87.5 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAI98269.1 - 0.097 12.2 0.6 3.4 7.3 0.4 3.1 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase BAAT_C PF08840.6 OAI98269.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal UBN2 PF14223.1 OAI98273.1 - 6.2e-15 55.0 0.1 1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAI98273.1 - 3.3e-14 52.4 0.0 4.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 OAI98273.1 - 2.7e-05 23.4 2.9 0.0001 21.6 0.1 3.0 3 1 1 4 4 4 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 OAI98273.1 - 8.7e-05 22.1 0.1 0.00021 20.9 0.0 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type eIF3g PF12353.3 OAI98273.1 - 0.0053 16.6 1.2 0.011 15.7 0.8 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G MULE PF10551.4 OAI98280.1 - 1.5e-19 69.9 0.0 2.8e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAI98280.1 - 1.2e-07 30.6 0.0 2e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Transposase, Mutator family DUF1370 PF07114.6 OAI98310.1 - 0.17 11.0 9.5 0.2 10.8 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1370) DUF1120 PF06551.7 OAI98310.1 - 0.31 11.3 4.1 0.49 10.7 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) DUF606 PF04657.8 OAI98310.1 - 3.7 7.6 12.5 3.2 7.8 5.7 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF606 BAF1_ABF1 PF04684.8 OAI98311.1 - 0.42 9.4 3.4 0.95 8.2 0.5 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor TSC22 PF01166.13 OAI98327.1 - 0.0019 18.1 2.6 0.0024 17.8 0.1 2.2 2 0 0 2 2 2 1 TSC-22/dip/bun family DUF972 PF06156.8 OAI98327.1 - 0.022 15.1 3.4 0.23 11.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) GAS PF13851.1 OAI98327.1 - 0.079 12.1 5.3 1.3 8.1 1.6 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ERM PF00769.14 OAI98327.1 - 1.1 8.7 10.1 0.11 11.9 2.0 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Rab5-bind PF09311.6 OAI98327.1 - 9.8 6.0 13.6 43 3.9 9.4 2.0 1 1 0 1 1 1 0 Rabaptin-like protein Ribosomal_60s PF00428.14 OAI98328.1 - 1.1e-21 76.9 9.8 1.8e-21 76.3 6.8 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sulf_transp PF04143.9 OAI98328.1 - 0.0017 18.3 1.0 0.0035 17.3 0.7 1.6 1 0 0 1 1 1 1 Sulphur transport Sigma70_r1_1 PF03979.9 OAI98328.1 - 0.19 11.6 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 PSK_trans_fac PF07704.6 OAI98335.1 - 0.0075 16.9 1.1 0.014 16.0 0.8 1.4 1 0 0 1 1 1 1 Rv0623-like transcription factor NatB_MDM20 PF09797.4 OAI98335.1 - 0.01 14.5 0.1 0.02 13.5 0.0 1.5 1 1 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF4618 PF15397.1 OAI98335.1 - 0.13 11.5 0.5 0.47 9.7 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Thymidylat_synt PF00303.14 OAI98344.1 - 2e-112 374.6 0.0 2.6e-112 374.2 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.17 OAI98344.1 - 1.7e-29 102.9 0.2 4.8e-29 101.5 0.1 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF2235 PF09994.4 OAI98351.1 - 5.7e-45 153.8 0.0 2.1e-29 102.7 0.0 3.3 2 1 0 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) NTP_transferase PF00483.18 OAI98382.1 - 1.1e-39 136.2 0.0 1.7e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase MannoseP_isomer PF01050.13 OAI98382.1 - 3.2e-06 26.8 0.1 5.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase TAF4 PF05236.9 OAI98387.1 - 0.17 11.1 1.4 0.18 11.0 1.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Aminotran_1_2 PF00155.16 OAI98388.1 - 1e-18 67.4 0.0 1.5e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SecY PF00344.15 OAI98388.1 - 6.4e-15 54.9 0.0 9.7e-11 41.1 0.0 2.3 2 1 0 2 2 2 2 SecY translocase DUF883 PF05957.8 OAI98404.1 - 0.16 12.4 0.3 0.25 11.7 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) IDO PF01231.13 OAI98412.1 - 7e-121 403.5 0.0 1.4e-100 336.6 0.0 2.1 2 0 0 2 2 2 2 Indoleamine 2,3-dioxygenase GLE1 PF07817.8 OAI98415.1 - 2.5e-62 210.1 0.0 3.8e-62 209.5 0.0 1.3 1 0 0 1 1 1 1 GLE1-like protein Spore_coat_CotO PF14153.1 OAI98415.1 - 0.038 13.4 12.4 0.069 12.5 8.6 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Macoilin PF09726.4 OAI98415.1 - 0.34 9.1 15.2 0.49 8.6 10.6 1.3 1 0 0 1 1 1 0 Transmembrane protein RR_TM4-6 PF06459.7 OAI98415.1 - 2.4 7.9 14.0 5.3 6.8 9.7 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WYL PF13280.1 OAI98425.1 - 1.2e-26 93.6 0.1 1.9e-26 92.9 0.1 1.2 1 0 0 1 1 1 1 WYL domain HTH_Tnp_Tc3_2 PF01498.13 OAI98425.1 - 0.063 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Transposase TPR_12 PF13424.1 OAI98430.1 - 3.8e-27 94.0 30.6 2.4e-10 40.1 2.5 6.5 3 1 4 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.1 OAI98430.1 - 2e-07 30.6 37.2 0.0034 17.2 0.6 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.23 OAI98430.1 - 1.8e-06 27.2 1.7 0.29 10.7 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAI98430.1 - 2.1e-06 28.2 29.4 0.022 15.3 1.3 7.0 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAI98430.1 - 6.6e-06 25.6 17.2 0.26 11.2 0.0 8.4 9 0 0 9 9 8 1 Tetratricopeptide repeat Apc5 PF12862.2 OAI98430.1 - 3.4e-05 23.5 14.8 1.2 9.0 0.0 6.6 3 2 5 8 8 8 2 Anaphase-promoting complex subunit 5 TPR_8 PF13181.1 OAI98430.1 - 8.2e-05 22.1 14.6 0.48 10.3 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAI98430.1 - 0.00013 21.5 1.7 0.00013 21.5 1.2 5.8 5 2 2 7 7 7 1 TPR repeat YfdX PF10938.3 OAI98430.1 - 0.0039 16.8 7.7 1.5 8.4 0.1 5.4 5 2 0 5 5 5 1 YfdX protein DUF3856 PF12968.2 OAI98430.1 - 0.055 13.3 5.5 1.9 8.2 0.1 4.3 2 2 3 5 5 5 0 Domain of Unknown Function (DUF3856) DUF627 PF04781.7 OAI98430.1 - 0.069 12.7 2.8 2.9 7.5 0.0 4.1 5 0 0 5 5 4 0 Protein of unknown function (DUF627) TPR_7 PF13176.1 OAI98430.1 - 0.07 12.9 15.7 15 5.7 0.0 7.4 7 1 0 7 7 7 0 Tetratricopeptide repeat MCRS_N PF13325.1 OAI98430.1 - 0.17 11.3 0.4 87 2.5 0.0 3.6 3 1 1 4 4 4 0 N-terminal region of micro-spherule protein Utp11 PF03998.8 OAI98430.1 - 0.24 11.2 0.6 20 4.9 0.0 3.0 2 2 2 4 4 4 0 Utp11 protein Bundlin PF05307.6 OAI98430.1 - 0.54 10.1 2.6 7.2 6.5 0.0 3.8 3 2 2 5 5 5 0 Bundlin TPR_14 PF13428.1 OAI98430.1 - 2.6 8.8 25.2 38 5.2 0.2 9.1 9 1 1 10 10 10 0 Tetratricopeptide repeat Rop PF01815.11 OAI98436.1 - 0.14 11.6 0.6 0.22 10.9 0.4 1.4 1 0 0 1 1 1 0 Rop protein RVP PF00077.15 OAI98437.1 - 0.00094 19.0 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAI98437.1 - 0.00097 19.5 0.1 0.0023 18.3 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Phage_integrase PF00589.17 OAI98443.1 - 0.00042 20.0 0.0 0.00074 19.2 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family RVT_3 PF13456.1 OAI98444.1 - 0.0077 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like DNA_pol_viral_C PF00336.13 OAI98444.1 - 0.027 13.7 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain DUF89 PF01937.14 OAI98459.1 - 6.9e-107 357.3 0.0 1.2e-106 356.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function DUF89 PAZ PF02170.17 OAI98472.1 - 1.6e-11 43.6 0.0 2.2e-11 43.1 0.0 1.3 1 1 0 1 1 1 1 PAZ domain Aconitase_B_N PF11791.3 OAI98472.1 - 0.008 16.0 0.1 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Aconitate B N-terminal domain HTH_29 PF13551.1 OAI98472.1 - 0.03 14.4 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix AA_permease_2 PF13520.1 OAI98482.1 - 6.6e-08 31.4 5.5 6e-06 25.0 2.9 2.0 1 1 1 2 2 2 2 Amino acid permease RVT_1 PF00078.22 OAI98513.1 - 1.4e-17 63.7 0.0 3.2e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI98513.1 - 3.7e-16 59.3 0.0 1.1e-15 57.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain CpcD PF01383.16 OAI98513.1 - 0.087 13.0 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 CpcD/allophycocyanin linker domain NT5C PF06941.7 OAI98513.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Polysacc_deac_1 PF01522.16 OAI98521.1 - 3.9e-27 94.3 0.0 7.7e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Sporozoite_P67 PF05642.6 OAI98521.1 - 0.16 9.7 13.6 0.59 7.9 9.4 1.7 1 1 0 1 1 1 0 Sporozoite P67 surface antigen RVT_1 PF00078.22 OAI98531.1 - 4.8e-18 65.2 0.0 1.1e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAI98531.1 - 0.0022 18.4 0.1 0.0066 16.9 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI98531.1 - 0.062 13.1 0.3 0.24 11.2 0.2 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease MRP-S26 PF14943.1 OAI98538.1 - 2.5 7.6 8.2 1.6 8.2 3.4 2.0 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 PX PF00787.19 OAI98539.1 - 7e-21 74.1 0.0 1.1e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 PX domain DUF2360 PF10152.4 OAI98539.1 - 9.5 6.4 6.6 25 5.1 2.7 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) zf-CCHC PF00098.18 OAI98543.1 - 0.0016 18.2 2.5 0.0028 17.4 1.7 1.4 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 OAI98543.1 - 0.012 16.1 0.0 0.03 14.8 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.1 OAI98543.1 - 0.019 14.4 0.6 0.038 13.5 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.1 OAI98543.1 - 0.029 14.1 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease SPX PF03105.14 OAI98552.1 - 3.8e-29 102.3 4.4 3.1e-27 96.0 3.1 3.1 1 1 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.20 OAI98552.1 - 1.8e-06 27.5 7.3 3.2e-06 26.6 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAI98552.1 - 2.7e-06 27.1 7.1 5.5e-06 26.1 4.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 OAI98552.1 - 5.6e-06 25.9 6.9 5.6e-06 25.9 4.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAI98552.1 - 6.1e-06 25.9 10.8 1.5e-05 24.7 7.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAI98552.1 - 7.3e-06 25.9 10.0 7.3e-06 25.9 6.9 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAI98552.1 - 0.00066 19.3 7.0 0.00066 19.3 4.8 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAI98552.1 - 0.002 17.8 5.4 0.0047 16.6 3.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 OAI98552.1 - 0.012 15.1 2.2 0.025 14.1 1.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 OAI98552.1 - 0.032 13.7 4.8 0.095 12.2 3.3 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 OAI98552.1 - 0.98 9.5 7.0 3.1 7.9 4.9 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger zf-P11 PF03854.9 OAI98552.1 - 1.5 8.3 6.2 2.8 7.4 4.3 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-DHHC PF01529.15 OAI98559.1 - 7.9 5.8 10.4 0.87 8.9 1.7 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF4064 PF13273.1 OAI98559.1 - 8.9 6.4 16.5 6.1 7.0 2.9 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) Pyridoxal_deC PF00282.14 OAI98563.1 - 4e-32 111.0 0.0 1.1e-30 106.3 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Phage_integrase PF00589.17 OAI98570.1 - 6.5e-05 22.6 0.0 8.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DUF4431 PF14485.1 OAI98570.1 - 0.077 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) RVT_3 PF13456.1 OAI98571.1 - 0.041 13.6 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like DNA_pol_viral_C PF00336.13 OAI98571.1 - 0.065 12.4 0.1 0.14 11.3 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain WD40 PF00400.27 OAI98577.1 - 1.2e-49 164.4 4.0 1.3e-11 43.9 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Tup_N PF08581.5 OAI98577.1 - 7.5e-19 67.7 1.2 7.5e-19 67.7 0.8 2.5 2 0 0 2 2 2 1 Tup N-terminal DUF1777 PF08648.7 OAI98577.1 - 0.0073 16.0 34.8 0.0073 16.0 24.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1777) PD40 PF07676.7 OAI98577.1 - 0.011 15.3 0.1 34 4.2 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nup160 PF11715.3 OAI98577.1 - 0.013 13.7 0.3 3.8 5.5 0.0 2.6 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 OAI98577.1 - 0.088 11.0 0.1 0.25 9.5 0.0 1.7 1 1 0 1 1 1 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 OAI98577.1 - 0.092 11.4 0.1 0.55 8.9 0.0 2.1 1 1 0 2 2 2 0 Nup133 N terminal like PRP38_assoc PF12871.2 OAI98577.1 - 0.15 12.6 38.5 0.027 15.0 23.5 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term IncA PF04156.9 OAI98577.1 - 1.3 8.6 24.3 4.1 6.9 0.0 2.7 2 1 0 2 2 2 0 IncA protein RRM_1 PF00076.17 OAI98590.1 - 4.1e-09 35.9 0.0 9.6e-09 34.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAI98590.1 - 6.8e-08 32.3 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) LEA_4 PF02987.11 OAI98590.1 - 0.00067 19.4 4.8 0.00067 19.4 3.4 2.8 2 1 1 3 3 3 1 Late embryogenesis abundant protein RRM_5 PF13893.1 OAI98590.1 - 0.0051 16.6 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF883 PF05957.8 OAI98590.1 - 0.014 15.7 2.0 0.014 15.7 1.4 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1798 PF08807.5 OAI98590.1 - 0.24 11.1 2.9 0.19 11.4 0.5 1.9 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) YtxH PF12732.2 OAI98590.1 - 2.3 8.6 15.9 21 5.5 6.6 3.7 2 1 0 2 2 2 0 YtxH-like protein HMGL-like PF00682.14 OAI98595.1 - 1e-61 208.6 0.0 1.5e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 OAI98595.1 - 3.4e-18 65.7 0.1 3.6e-09 36.5 0.0 2.6 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain Bax1-I PF01027.15 OAI98602.1 - 3.1e-44 151.0 20.9 3.7e-44 150.7 14.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF3464 PF11947.3 OAI98602.1 - 1.4 8.3 6.2 2 7.8 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3464) Pox_I5 PF04713.7 OAI98602.1 - 5 6.9 8.7 1.1 8.9 0.1 2.9 2 1 1 3 3 3 0 Poxvirus protein I5 Nop53 PF07767.6 OAI98603.1 - 1.2e-21 77.1 0.5 8.4e-21 74.4 0.4 1.9 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) PGAP1 PF07819.8 OAI98611.1 - 0.0002 21.0 0.0 0.00042 19.9 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 OAI98611.1 - 0.0034 17.1 0.0 0.0074 16.0 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAI98611.1 - 0.018 14.9 0.2 0.04 13.8 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Pex14_N PF04695.8 OAI98618.1 - 0.18 11.8 2.9 0.14 12.1 0.4 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RVT_3 PF13456.1 OAI98619.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like OPT PF03169.10 OAI98625.1 - 1.1e-93 314.7 40.9 1.3e-93 314.5 28.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3353 PF11833.3 OAI98625.1 - 0.68 9.3 4.2 0.7 9.3 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) CBFB_NFYA PF02045.10 OAI98655.1 - 6.7e-20 71.3 23.4 2.5e-11 43.9 3.6 3.4 2 2 0 2 2 2 2 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B SR-25 PF10500.4 OAI98655.1 - 1.5 8.2 16.9 0.059 12.8 3.0 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein CYSTM PF12734.2 OAI98661.1 - 0.065 13.3 0.2 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Asp_protease_2 PF13650.1 OAI98669.1 - 0.00043 20.7 0.0 0.00086 19.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI98669.1 - 0.004 16.9 0.0 0.014 15.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAI98669.1 - 0.065 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Pyocin_S PF06958.7 OAI98670.1 - 1.8 8.9 4.5 8.6 6.7 0.2 2.1 2 0 0 2 2 2 0 S-type Pyocin AA_permease PF00324.16 OAI98677.1 - 2.2e-27 95.5 3.8 2.6e-27 95.3 2.6 1.0 1 0 0 1 1 1 1 Amino acid permease SR-25 PF10500.4 OAI98678.1 - 9.2 5.6 14.2 15 5.0 9.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CRAL_TRIO PF00650.15 OAI98690.1 - 6.5e-17 61.4 0.0 7.5e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain G_glu_transpept PF01019.16 OAI98691.1 - 4.4e-140 467.5 0.0 5.4e-140 467.2 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Exo_endo_phos PF03372.18 OAI98697.1 - 0.0012 18.8 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 OAI98697.1 - 0.0028 17.2 0.0 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase NIT PF08376.5 OAI98698.1 - 0.036 13.6 0.2 0.081 12.4 0.2 1.5 1 0 0 1 1 1 0 Nitrate and nitrite sensing TFIID_20kDa PF03847.8 OAI98719.1 - 7.9e-32 109.3 0.3 1.2e-31 108.7 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 OAI98719.1 - 0.0084 16.1 0.1 0.019 15.0 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Occludin_ELL PF07303.8 OAI98719.1 - 0.051 14.3 0.2 0.051 14.3 0.1 2.3 2 0 0 2 2 2 0 Occludin homology domain R3H-assoc PF13902.1 OAI98719.1 - 0.29 11.1 2.5 7.7 6.4 0.0 3.3 3 1 1 4 4 4 0 R3H-associated N-terminal domain rve PF00665.21 OAI98725.1 - 1.7e-15 57.2 0.0 3.2e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAI98725.1 - 5.8e-15 55.2 0.0 1.2e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Denso_VP4 PF02336.10 OAI98725.1 - 0.4 9.6 0.0 0.67 8.8 0.0 1.3 1 0 0 1 1 1 0 Capsid protein VP4 SNARE_assoc PF09335.6 OAI98731.1 - 1.4e-21 76.9 7.8 2.8e-14 53.3 0.0 3.1 4 0 0 4 4 4 2 SNARE associated Golgi protein Phytoreo_S7 PF07236.6 OAI98732.1 - 0.1 10.8 0.0 0.1 10.8 0.0 1.0 1 0 0 1 1 1 0 Phytoreovirus S7 protein Peptidase_C48 PF02902.14 OAI98740.1 - 1.3e-12 47.8 0.1 1.3e-12 47.8 0.1 2.1 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain SWIM PF04434.12 OAI98740.1 - 0.099 12.1 0.8 0.21 11.1 0.6 1.5 1 0 0 1 1 1 0 SWIM zinc finger MTP18 PF10558.4 OAI98748.1 - 2.9e-23 82.4 2.5 3.6e-23 82.0 1.7 1.3 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DSHCT PF08148.7 OAI98749.1 - 1.7e-24 86.0 0.1 3.3e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain Herpes_U47 PF05467.6 OAI98756.1 - 0.069 10.9 0.0 0.11 10.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 CBFD_NFYB_HMF PF00808.18 OAI98789.1 - 1.5e-14 53.7 0.0 1.7e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAI98789.1 - 3.2e-06 27.1 0.0 3.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 OAI98789.1 - 0.0045 16.7 0.1 0.0045 16.7 0.0 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region TRAM PF01938.15 OAI98789.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.4 1 1 0 1 1 1 0 TRAM domain 5-FTHF_cyc-lig PF01812.15 OAI98790.1 - 4.6e-28 98.2 0.0 8.6e-27 94.1 0.0 2.2 2 0 0 2 2 2 1 5-formyltetrahydrofolate cyclo-ligase family PMT PF02366.13 OAI98796.1 - 1.4e-06 27.8 6.6 0.0015 17.9 0.5 2.5 3 0 0 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase Ycf9 PF01737.12 OAI98796.1 - 0.1 12.0 0.0 0.1 12.0 0.0 2.3 2 1 0 2 2 2 0 YCF9 DNA_pol_phi PF04931.8 OAI98806.1 - 3.4e-13 48.3 0.0 7.1e-08 30.7 0.0 3.2 3 0 0 3 3 3 2 DNA polymerase phi CRISPR_Cse2 PF09485.5 OAI98806.1 - 0.0079 16.2 1.4 0.024 14.6 1.0 1.8 1 0 0 1 1 1 1 CRISPR-associated protein Cse2 (CRISPR_cse2) RVT_1 PF00078.22 OAI98823.1 - 4.8e-16 58.7 0.0 1e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BCDHK_Adom3 PF10436.4 OAI98833.1 - 0.12 11.8 1.1 0.16 11.4 0.8 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase ATP11 PF06644.6 OAI98833.1 - 0.17 11.3 16.5 0.23 10.9 11.4 1.3 1 0 0 1 1 1 0 ATP11 protein Glycohydro_20b2 PF14845.1 OAI98833.1 - 0.2 12.3 2.8 0.27 11.8 1.9 1.2 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like FAM74 PF15026.1 OAI98833.1 - 0.85 9.2 4.6 1.1 8.9 3.2 1.4 1 0 0 1 1 1 0 FAM74 protein Neur_chan_memb PF02932.11 OAI98833.1 - 1 9.2 9.2 1.2 8.9 6.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Orbi_VP5 PF00901.12 OAI98833.1 - 1.7 6.7 13.9 2 6.5 9.6 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF1311 PF07007.7 OAI98833.1 - 4.1 7.5 10.9 2.1 8.4 5.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1311) Syntaxin-6_N PF09177.6 OAI98833.1 - 6.6 7.2 12.6 8.5 6.8 1.6 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF334 PF03904.8 OAI98833.1 - 8.1 5.6 13.1 5.2 6.3 8.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF334) Uricase PF01014.13 OAI98834.1 - 2e-54 183.3 0.0 8.6e-34 116.5 0.0 2.6 2 1 0 2 2 2 2 Uricase 6PGD PF00393.14 OAI98842.1 - 1.9e-116 388.3 0.0 2.1e-116 388.2 0.0 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain Aldo_ket_red PF00248.16 OAI98843.1 - 2.6e-56 190.5 0.0 2.9e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DBD_Tnp_Mut PF03108.10 OAI98849.1 - 5.5e-14 51.4 1.3 1.2e-13 50.4 0.9 1.4 1 0 0 1 1 1 1 MuDR family transposase Ima1_N PF09779.4 OAI98849.1 - 0.03 14.8 1.8 0.033 14.6 0.1 1.8 2 0 0 2 2 2 0 Ima1 N-terminal domain TSGP1 PF07771.6 OAI98857.1 - 0.023 14.6 1.3 0.023 14.6 0.9 2.3 3 0 0 3 3 3 0 Tick salivary peptide group 1 SSP160 PF06933.6 OAI98857.1 - 0.56 8.1 5.5 0.48 8.3 3.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1566 PF07603.6 OAI98866.1 - 0.0028 17.3 0.4 0.0069 16.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1566) zf-BED PF02892.10 OAI98866.1 - 0.012 15.3 0.1 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 BED zinc finger Stm1_N PF09598.5 OAI98866.1 - 0.043 14.5 4.2 0.043 14.5 2.9 3.2 4 0 0 4 4 4 0 Stm1 Dimer_Tnp_hAT PF05699.9 OAI98867.1 - 4.8e-11 42.1 0.0 1.1e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAI98867.1 - 5e-05 23.2 0.0 0.00022 21.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) RVT_1 PF00078.22 OAI98875.1 - 1.9e-15 56.8 0.0 3.9e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAI98885.1 - 1.9e-16 60.0 0.0 3.8e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI98885.1 - 2.8e-07 30.6 0.0 0.011 15.8 0.0 2.5 1 1 1 2 2 2 2 Integrase core domain TniQ PF06527.6 OAI98897.1 - 0.27 11.4 2.0 0.44 10.7 1.4 1.3 1 0 0 1 1 1 0 TniQ KdpC PF02669.10 OAI98897.1 - 0.79 9.3 4.9 1.5 8.4 3.4 1.4 1 0 0 1 1 1 0 K+-transporting ATPase, c chain DDE_1 PF03184.14 OAI98903.1 - 1.2e-28 99.6 0.0 1.5e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Mcm10 PF09332.6 OAI98953.1 - 0.054 12.8 0.0 0.06 12.6 0.0 1.1 1 0 0 1 1 1 0 Mcm10 replication factor DUF1974 PF09317.6 OAI98954.1 - 0.0017 17.7 0.1 0.0026 17.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1974) Strabismus PF06638.6 OAI98954.1 - 0.054 11.8 0.1 0.073 11.3 0.0 1.1 1 0 0 1 1 1 0 Strabismus protein MFS_1 PF07690.11 OAI98961.1 - 2e-09 36.6 24.7 2e-09 36.6 17.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Clat_adaptor_s PF01217.15 OAI99000.1 - 9.8e-54 180.9 1.3 1.1e-53 180.8 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mito_carr PF00153.22 OAI99001.1 - 4.6e-55 183.3 0.3 3.8e-20 71.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 OAI99010.1 - 1.2e-35 122.9 0.0 1.6e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI99010.1 - 7e-17 61.3 0.0 1.6e-16 60.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI99010.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pantoate_transf PF02548.10 OAI99022.1 - 0.1 11.6 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase STAG PF08514.6 OAI99023.1 - 0.13 12.0 0.1 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 STAG domain RVT_2 PF07727.9 OAI99033.1 - 3e-85 285.1 0.0 4.1e-85 284.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI99033.1 - 1.6e-22 79.8 0.2 5.4e-21 74.9 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAI99033.1 - 9.5e-06 25.1 0.0 2.3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAI99033.1 - 0.0084 15.6 0.0 0.042 13.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain PRP21_like_P PF12230.3 OAI99033.1 - 0.13 11.7 5.8 0.22 11.0 4.0 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein ICMT PF04140.9 OAI99040.1 - 7.1e-14 51.7 0.4 2.8e-13 49.8 0.3 1.8 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 OAI99040.1 - 5.1e-07 29.7 0.8 2.8e-06 27.3 0.6 1.9 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 OAI99040.1 - 0.01 14.4 0.0 0.53 8.7 0.0 2.1 2 0 0 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family TRAPPC10 PF12584.3 OAI99050.1 - 1.8e-22 79.4 0.0 3.1e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 DUF1279 PF06916.8 OAI99051.1 - 0.028 14.7 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) E1-E2_ATPase PF00122.15 OAI99063.1 - 3.4e-61 206.2 0.6 4.7e-61 205.7 0.4 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 OAI99063.1 - 3e-11 42.6 0.1 8.5e-11 41.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.21 OAI99063.1 - 0.0045 17.4 0.1 0.009 16.4 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAI99063.1 - 0.093 12.8 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase TPR_11 PF13414.1 OAI99076.1 - 2.1e-10 40.1 8.5 1.7e-09 37.1 0.7 3.2 3 0 0 3 3 3 2 TPR repeat DnaJ PF00226.26 OAI99076.1 - 7.6e-06 25.5 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.23 OAI99076.1 - 0.0026 17.2 1.1 0.025 14.1 0.8 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat CytochromB561_N PF09786.4 OAI99076.1 - 0.013 13.9 1.9 0.042 12.3 1.3 1.9 1 0 0 1 1 1 0 Cytochrome B561, N terminal TPR_2 PF07719.12 OAI99076.1 - 0.18 11.7 13.5 0.027 14.3 1.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAI99076.1 - 2.1 8.3 5.5 0.24 11.3 0.4 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Carboxyl_trans PF01039.17 OAI99096.1 - 5.2e-141 470.3 0.0 6.7e-141 470.0 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ACCA PF03255.9 OAI99096.1 - 0.036 13.6 0.2 5.5 6.5 0.0 2.7 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ECH PF00378.15 OAI99096.1 - 0.19 10.8 0.8 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase family Alpha-amylase PF00128.19 OAI99114.1 - 0.016 14.6 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha amylase, catalytic domain CK_II_beta PF01214.13 OAI99132.1 - 3.9e-77 257.9 0.1 1.1e-76 256.4 0.0 1.8 2 0 0 2 2 2 1 Casein kinase II regulatory subunit CDC27 PF09507.5 OAI99132.1 - 0.6 9.2 17.5 1.3 8.1 12.1 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Band_3_cyto PF07565.8 OAI99132.1 - 0.75 9.2 5.5 1 8.8 3.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Suf PF05843.9 OAI99132.1 - 2 8.0 7.5 4.1 7.0 5.2 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-CCHC PF00098.18 OAI99142.1 - 1.9e-06 27.5 3.1 3.1e-06 26.8 2.2 1.3 1 0 0 1 1 1 1 Zinc knuckle Yae1_N PF09811.4 OAI99142.1 - 7e-05 22.2 9.1 0.00014 21.3 6.3 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal zf-CCHC_2 PF13696.1 OAI99142.1 - 0.00033 20.0 0.3 0.00093 18.6 0.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 OAI99142.1 - 0.6 9.8 3.1 1.1 8.9 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle MRP-S25 PF13741.1 OAI99153.1 - 0.09 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 Phage_lambd_GpG PF06894.6 OAI99178.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage lambda minor tail protein (GpG) Asp_protease_2 PF13650.1 OAI99190.1 - 0.00012 22.5 0.0 0.00026 21.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI99190.1 - 0.004 16.9 0.1 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAI99190.1 - 0.0052 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 OAI99190.1 - 0.0093 16.0 0.2 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein dUTPase PF00692.14 OAI99190.1 - 0.025 14.0 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 dUTPase DHHW PF14286.1 OAI99198.1 - 0.0096 15.2 0.8 0.016 14.5 0.6 1.3 1 0 0 1 1 1 1 DHHW protein ACOX PF01756.14 OAI99198.1 - 0.11 11.8 0.2 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Acyl-CoA oxidase GATA PF00320.22 OAI99210.1 - 2.9e-05 23.3 5.7 0.0001 21.5 2.9 2.3 1 1 1 2 2 2 1 GATA zinc finger ADK_lid PF05191.9 OAI99210.1 - 0.082 12.5 1.6 0.17 11.5 1.1 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid DNA_pol_viral_C PF00336.13 OAI99223.1 - 0.074 12.3 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain AAA PF00004.24 OAI99236.1 - 2.2e-17 63.5 0.0 8.3e-17 61.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 OAI99236.1 - 1.5e-16 60.1 0.0 2.8e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 OAI99236.1 - 3.3e-16 59.3 0.0 2.2e-14 53.4 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 OAI99236.1 - 2.7e-11 42.8 0.0 9.8e-09 34.4 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 OAI99236.1 - 3.6e-06 27.1 0.2 0.015 15.4 0.0 2.7 2 1 1 3 3 2 2 AAA domain RuvB_N PF05496.7 OAI99236.1 - 1.2e-05 24.4 0.0 2.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 OAI99236.1 - 3e-05 23.9 0.0 8.4e-05 22.4 0.0 1.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 OAI99236.1 - 3.4e-05 22.8 0.0 5.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.8 OAI99236.1 - 4.2e-05 23.1 0.0 0.00011 21.7 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_11 PF13086.1 OAI99236.1 - 5.9e-05 22.7 0.1 0.0039 16.8 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 OAI99236.1 - 6.1e-05 22.7 0.1 0.00024 20.8 0.0 2.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 OAI99236.1 - 0.00011 21.8 0.0 0.00036 20.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 OAI99236.1 - 0.00019 21.4 0.0 0.0031 17.5 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_3 PF07726.6 OAI99236.1 - 0.00031 20.3 0.0 0.00064 19.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 OAI99236.1 - 0.00056 19.4 0.3 0.38 10.1 0.0 2.3 1 1 1 2 2 2 2 AAA-like domain AAA_25 PF13481.1 OAI99236.1 - 0.0014 18.0 0.0 0.0075 15.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 OAI99236.1 - 0.0016 18.0 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 OAI99236.1 - 0.0017 17.9 0.0 0.0044 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 OAI99236.1 - 0.0068 15.9 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 OAI99236.1 - 0.017 14.5 0.1 0.24 10.8 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase T2SE PF00437.15 OAI99236.1 - 0.021 13.7 0.0 0.039 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 OAI99236.1 - 0.029 13.8 0.0 0.082 12.3 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.10 OAI99236.1 - 0.031 14.0 0.0 0.25 11.1 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 OAI99236.1 - 0.042 14.1 0.0 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter IstB_IS21 PF01695.12 OAI99236.1 - 0.054 12.8 0.0 0.19 11.1 0.0 1.9 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 OAI99236.1 - 0.092 12.6 0.0 0.18 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 OAI99236.1 - 0.097 11.8 0.0 0.37 9.9 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 OAI99236.1 - 0.1 12.1 0.0 0.32 10.5 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 OAI99236.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.8 2 1 0 2 2 1 0 AAA domain COX14 PF14880.1 OAI99237.1 - 0.0028 17.2 0.2 0.0048 16.4 0.1 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c assembly DUF2530 PF10745.4 OAI99237.1 - 0.072 13.0 0.2 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Pro_dh-DNA_bdg PF14850.1 OAI99237.1 - 0.15 12.2 0.0 0.19 11.9 0.0 1.1 1 0 0 1 1 1 0 DNA-binding domain of Proline dehydrogenase FAD_binding_4 PF01565.18 OAI99248.1 - 3.6e-15 55.6 0.3 6.6e-10 38.5 0.0 4.1 5 0 0 5 5 5 2 FAD binding domain BBE PF08031.7 OAI99248.1 - 3.7e-07 29.9 0.0 8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Med3 PF11593.3 OAI99248.1 - 0.58 9.3 11.4 1.1 8.3 7.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SH3_1 PF00018.23 OAI99250.1 - 4.5e-11 41.9 0.0 7.5e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAI99250.1 - 4.4e-09 35.7 0.0 7.1e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAI99250.1 - 2.7e-07 29.9 0.0 4.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Lipocalin_2 PF08212.7 OAI99261.1 - 5.5e-16 58.6 0.0 7.6e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin_2 PF08212.7 OAI99262.1 - 1.1e-07 31.7 0.0 3e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Lipocalin-like domain MORN_2 PF07661.8 OAI99262.1 - 0.15 12.1 0.1 0.42 10.7 0.0 1.8 1 0 0 1 1 1 0 MORN repeat variant DDE_3 PF13358.1 OAI99273.1 - 6.8e-20 71.2 0.0 1.1e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 OAI99273.1 - 0.0023 18.0 0.1 0.0055 16.8 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_IS630 PF01710.11 OAI99273.1 - 0.0039 16.8 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 OAI99273.1 - 0.0051 17.5 0.9 0.02 15.6 0.0 2.3 2 1 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.1 OAI99273.1 - 0.011 15.2 2.1 0.035 13.6 0.1 2.4 2 1 0 2 2 2 0 Winged helix-turn helix DDE_1 PF03184.14 OAI99273.1 - 0.11 11.6 0.0 0.35 9.9 0.0 1.8 2 0 0 2 2 2 0 DDE superfamily endonuclease AAA PF00004.24 OAI99286.1 - 4.6e-17 62.4 0.0 5.1e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LSM PF01423.17 OAI99294.1 - 6.6e-15 54.4 0.0 8.5e-15 54.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain PRP3 PF08572.5 OAI99295.1 - 1.3e-61 207.8 5.7 2.4e-61 206.9 4.0 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 OAI99295.1 - 6.6e-28 96.9 0.0 1.5e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) TRAP-gamma PF07074.7 OAI99295.1 - 0.31 10.5 1.9 0.63 9.5 1.3 1.5 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) TPR_12 PF13424.1 OAI99311.1 - 1.4e-14 53.7 32.4 7e-05 22.6 1.0 7.4 3 3 4 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 OAI99311.1 - 1.2e-07 31.3 24.8 0.0084 16.0 0.4 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAI99311.1 - 2.9e-07 29.8 19.8 0.047 13.6 0.3 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 OAI99311.1 - 0.00013 21.5 1.7 2.5 8.0 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAI99311.1 - 0.00035 20.9 22.5 0.092 13.4 0.1 8.3 7 2 2 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAI99311.1 - 0.0014 18.8 9.9 2.4 8.5 0.0 6.1 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAI99311.1 - 0.0057 16.2 12.6 0.061 12.9 0.5 4.9 5 1 1 6 6 5 1 TPR repeat MIT PF04212.13 OAI99311.1 - 0.0094 15.8 10.2 0.047 13.5 1.3 4.2 4 0 0 4 4 3 1 MIT (microtubule interacting and transport) domain MTBP_C PF14920.1 OAI99311.1 - 0.014 14.9 1.1 0.026 14.0 0.5 1.6 1 1 0 1 1 1 0 MDM2-binding PPR PF01535.15 OAI99311.1 - 0.02 14.8 3.3 24 5.2 0.0 4.8 5 0 0 5 5 4 0 PPR repeat TPR_1 PF00515.23 OAI99311.1 - 0.024 14.2 11.0 0.26 10.9 0.0 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat Apc5 PF12862.2 OAI99311.1 - 0.031 14.0 15.6 0.72 9.7 0.7 5.7 3 2 3 6 6 6 0 Anaphase-promoting complex subunit 5 PPR_1 PF12854.2 OAI99311.1 - 0.8 9.2 5.2 2.7 7.5 0.1 3.2 3 0 0 3 3 3 0 PPR repeat TPR_7 PF13176.1 OAI99311.1 - 1 9.3 7.9 4.1 7.4 0.1 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAI99311.1 - 6.9 7.4 25.0 17 6.2 0.6 7.6 8 0 0 8 8 7 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.12 OAI99324.1 - 4.3e-93 310.4 0.0 2.5e-82 275.2 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 OAI99324.1 - 1.2e-41 141.2 0.3 3e-41 140.0 0.1 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 OAI99324.1 - 9.6e-35 119.0 0.0 3e-16 59.5 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 OAI99324.1 - 2.1e-21 76.4 0.0 9.9e-16 58.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAI99324.1 - 2.4e-18 66.0 0.0 3e-07 29.4 0.0 3.2 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 OAI99324.1 - 6e-10 38.7 0.0 6.3e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 OAI99324.1 - 2e-08 33.9 0.0 0.00012 21.5 0.0 2.6 2 1 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 OAI99324.1 - 1.2e-05 24.9 0.0 0.071 12.5 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 OAI99324.1 - 1.5e-05 24.3 0.1 0.02 14.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 OAI99324.1 - 2.8e-05 24.0 0.0 9.5e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain RVT_3 PF13456.1 OAI99336.1 - 2.4e-06 27.2 0.0 5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like Retrotrans_gag PF03732.12 OAI99357.1 - 4.3e-12 45.9 0.6 8.2e-12 45.0 0.1 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein UDPGT PF00201.13 OAI99370.1 - 5.5e-15 54.8 0.1 8.4e-15 54.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GHMP_kinases_C PF08544.8 OAI99370.1 - 0.013 15.6 0.1 0.58 10.3 0.0 2.5 1 1 0 1 1 1 0 GHMP kinases C terminal Glyco_trans_1_3 PF13528.1 OAI99370.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 UDPGT PF00201.13 OAI99371.1 - 7e-14 51.2 0.1 9.3e-14 50.8 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 OAI99371.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 MULE PF10551.4 OAI99385.1 - 4.6e-09 36.3 0.0 1.2e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAI99385.1 - 0.0019 16.8 0.0 0.0043 15.6 0.0 1.5 1 0 0 1 1 1 1 Transposase, Mutator family TT_ORF2 PF02957.10 OAI99385.1 - 0.027 15.1 2.1 0.064 13.9 1.4 1.6 1 0 0 1 1 1 0 TT viral ORF2 Spectrin PF00435.16 OAI99422.1 - 0.00098 19.3 0.5 0.0014 18.8 0.4 1.2 1 0 0 1 1 1 1 Spectrin repeat Cep57_MT_bd PF06657.8 OAI99422.1 - 0.0021 17.9 0.2 1.7 8.6 0.0 2.1 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 DMPK_coil PF08826.5 OAI99422.1 - 0.0065 16.3 0.4 0.017 15.0 0.3 1.7 1 0 0 1 1 1 1 DMPK coiled coil domain like DUF1351 PF07083.6 OAI99422.1 - 0.048 13.2 0.2 0.056 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) Syntaxin-6_N PF09177.6 OAI99422.1 - 0.084 13.2 0.9 0.57 10.6 0.3 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal KfrA_N PF11740.3 OAI99422.1 - 0.52 10.7 4.3 1.6 9.1 3.0 1.8 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term UPF0029 PF01205.14 OAI99435.1 - 1.2e-24 86.1 0.0 7.6e-24 83.5 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.17 OAI99435.1 - 0.0015 18.3 0.0 0.0044 16.8 0.0 1.7 1 1 0 1 1 1 1 RWD domain PsbX PF06596.6 OAI99460.1 - 0.047 13.3 1.5 0.094 12.4 1.1 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) RVT_1 PF00078.22 OAI99481.1 - 3.3e-26 91.9 0.0 5.3e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAI99481.1 - 3.3e-14 53.3 0.0 6.5e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAI99481.1 - 0.00038 20.1 0.0 0.0011 18.6 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like Rota_NSP4 PF01452.11 OAI99481.1 - 0.31 10.3 0.0 0.56 9.5 0.0 1.3 1 0 0 1 1 1 0 Rotavirus non structural protein Peroxidase_2 PF01328.12 OAI99493.1 - 3.2e-19 68.7 0.0 4.5e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 zf-C2H2 PF00096.21 OAI99506.1 - 9.9e-05 22.4 0.1 0.0003 20.9 0.0 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAI99506.1 - 0.055 13.8 0.4 0.18 12.2 0.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger RVT_2 PF07727.9 OAI99524.1 - 7.8e-68 228.0 0.0 3.8e-61 206.1 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI99524.1 - 1.6e-20 73.4 0.0 6.3e-20 71.4 0.0 2.1 3 0 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.1 OAI99524.1 - 1.6e-06 27.6 0.0 2.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain RVP PF00077.15 OAI99524.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Autotransporter PF03797.14 OAI99524.1 - 0.12 11.6 0.1 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Autotransporter beta-domain zf-CCHC PF00098.18 OAI99524.1 - 0.13 12.2 5.4 0.32 10.9 3.7 1.7 1 0 0 1 1 1 0 Zinc knuckle Phage_holin_2 PF04550.7 OAI99536.1 - 0.057 13.5 6.1 3.9 7.6 0.3 3.1 2 1 1 3 3 3 0 Phage holin family 2 DUF616 PF04765.8 OAI99546.1 - 0.018 14.2 0.2 0.024 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF616) KaiC PF06745.8 OAI99546.1 - 0.058 12.5 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 KaiC zf-CCHC_4 PF14392.1 OAI99546.1 - 2.2 8.0 8.9 0.3 10.7 1.4 2.4 2 0 0 2 2 2 0 Zinc knuckle DDE_3 PF13358.1 OAI99577.1 - 4.3e-32 110.8 0.0 8e-32 109.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 OAI99577.1 - 0.00032 19.8 0.0 0.00054 19.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 OAI99577.1 - 0.00068 19.7 0.0 0.0024 17.9 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain HTH_32 PF13565.1 OAI99577.1 - 0.001 19.8 0.0 0.0056 17.4 0.0 2.2 2 1 1 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.1 OAI99577.1 - 0.015 14.8 0.1 0.045 13.2 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix HTH_29 PF13551.1 OAI99577.1 - 0.061 13.4 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 OAI99577.1 - 0.16 10.7 0.0 0.38 9.4 0.0 1.6 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain ABC_tran PF00005.22 OAI99624.1 - 1.3e-16 61.1 0.0 6.3e-16 58.9 0.0 2.0 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 OAI99624.1 - 1.6e-10 41.4 0.1 0.00012 22.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 OAI99624.1 - 9.7e-07 28.1 0.0 0.0049 15.9 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 OAI99624.1 - 0.0002 20.8 0.0 0.00042 19.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 OAI99624.1 - 0.0023 17.3 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 OAI99624.1 - 0.0028 16.9 0.1 1 8.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 OAI99624.1 - 0.0074 16.2 0.1 0.037 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 OAI99624.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.1 OAI99624.1 - 0.017 15.0 1.1 0.017 15.0 0.1 1.7 2 1 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 OAI99624.1 - 0.025 14.5 0.0 0.043 13.7 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.16 OAI99624.1 - 0.034 13.3 0.1 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_10 PF12846.2 OAI99624.1 - 0.041 13.3 0.7 0.18 11.2 0.1 2.0 1 1 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 OAI99624.1 - 0.045 14.0 0.0 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 OAI99624.1 - 0.05 12.7 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 OAI99624.1 - 0.059 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 OAI99624.1 - 0.071 13.6 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein MutS_V PF00488.16 OAI99624.1 - 0.075 12.4 0.1 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 MutS domain V Sigma54_activat PF00158.21 OAI99624.1 - 0.1 12.0 0.2 10 5.5 0.1 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 OAI99624.1 - 0.14 12.3 0.2 1.5 9.0 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 OAI99624.1 - 0.25 12.1 1.2 0.43 11.4 0.3 2.0 2 1 0 2 2 1 0 AAA domain Dus PF01207.12 OAI99635.1 - 5.2e-63 212.7 0.0 9.4e-62 208.6 0.0 2.1 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TPR_11 PF13414.1 OAI99635.1 - 7e-10 38.4 2.1 0.00025 20.6 0.4 3.5 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 OAI99635.1 - 1.6e-05 24.2 3.5 1.3 8.7 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAI99635.1 - 0.0032 18.0 6.1 0.27 11.9 0.0 3.8 4 1 1 5 5 5 3 Tetratricopeptide repeat IL6 PF00489.12 OAI99635.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family His_biosynth PF00977.16 OAI99635.1 - 0.095 11.9 0.0 0.47 9.6 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein TPR_12 PF13424.1 OAI99635.1 - 0.1 12.5 3.2 1.2 9.1 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAI99635.1 - 0.14 12.1 6.8 0.75 9.8 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat eIF3_subunit PF08597.5 OAI99667.1 - 0.015 14.8 9.9 0.021 14.3 6.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1227 PF06777.6 OAI99667.1 - 0.086 12.5 0.4 0.14 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1227) ATP11 PF06644.6 OAI99667.1 - 0.13 11.7 4.3 0.19 11.2 3.0 1.2 1 0 0 1 1 1 0 ATP11 protein Complex1_LYR PF05347.10 OAI99667.1 - 0.24 11.2 1.2 0.57 10.0 0.8 1.6 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DUF2457 PF10446.4 OAI99667.1 - 0.31 9.7 6.6 0.43 9.2 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Tom37_C PF11801.3 OAI99667.1 - 0.92 9.3 2.9 1.4 8.7 2.0 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF4192 PF13830.1 OAI99667.1 - 1.8 8.1 11.7 3 7.3 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DUF605 PF04652.11 OAI99676.1 - 7 5.9 18.6 7.9 5.7 12.9 1.1 1 0 0 1 1 1 0 Vta1 like Asp PF00026.18 OAI99677.1 - 6e-24 84.8 6.1 1.9e-23 83.2 4.2 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAI99677.1 - 0.0003 20.7 1.9 0.0072 16.2 0.1 2.5 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAI99677.1 - 0.043 14.3 1.5 0.081 13.4 0.3 2.0 2 1 0 2 2 2 0 Aspartyl protease OppC_N PF12911.2 OAI99690.1 - 0.098 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Polysacc_deac_1 PF01522.16 OAI99691.1 - 2.5e-23 82.0 0.0 5.1e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF3292 PF11696.3 OAI99702.1 - 4.3e-12 44.7 1.3 2.6e-07 28.9 0.1 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF3292) PRT_C PF08372.5 OAI99702.1 - 4.1e-05 23.1 4.1 0.00059 19.3 0.8 2.4 1 1 1 2 2 2 2 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.12 OAI99702.1 - 0.018 14.6 5.5 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Reticulon PH_BEACH PF14844.1 OAI99702.1 - 0.031 14.1 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH Tox-GHH PF15636.1 OAI99721.1 - 0.022 14.3 0.7 0.11 12.0 0.0 2.4 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF572 PF04502.8 OAI99721.1 - 0.21 10.7 10.1 0.28 10.3 7.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DDE_Tnp_4 PF13359.1 OAI99722.1 - 1.4e-14 53.9 0.1 5.5e-14 52.0 0.0 1.9 1 1 1 2 2 2 1 DDE superfamily endonuclease Mnd1 PF03962.10 OAI99722.1 - 0.17 11.5 4.8 0.22 11.1 3.3 1.1 1 0 0 1 1 1 0 Mnd1 family Enkurin PF13864.1 OAI99722.1 - 0.18 12.0 6.0 0.31 11.2 4.1 1.3 1 0 0 1 1 1 0 Calmodulin-binding ABC2_membrane_3 PF12698.2 OAI99734.1 - 0.011 14.7 0.2 0.015 14.3 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein UPRTase PF14681.1 OAI99749.1 - 5.6e-50 169.4 0.0 6.2e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 OAI99749.1 - 0.00013 21.7 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain VAD1-2 PF15310.1 OAI99785.1 - 3.5 7.2 5.6 4 7.0 3.9 1.1 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling Vfa1 PF08432.5 OAI99785.1 - 5.3 7.0 13.7 6.1 6.8 9.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Spore_coat_CotO PF14153.1 OAI99785.1 - 6.7 6.1 10.0 7.5 5.9 6.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO RNA_pol_Rpc4 PF05132.9 OAI99785.1 - 8.5 6.3 6.9 11 6.0 4.8 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Herpes_gE PF02480.11 OAI99829.1 - 0.22 9.7 0.1 0.34 9.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E HSP70 PF00012.15 OAI99842.1 - 2e-71 240.7 0.6 2.3e-71 240.5 0.4 1.0 1 0 0 1 1 1 1 Hsp70 protein FtsA PF14450.1 OAI99842.1 - 0.01 15.6 0.1 0.049 13.4 0.1 2.2 1 1 0 1 1 1 0 Cell division protein FtsA RskA PF10099.4 OAI99842.1 - 0.025 14.3 1.2 0.045 13.4 0.4 1.8 2 1 0 2 2 2 0 Anti-sigma-K factor rskA GCR1_C PF12550.3 OAI99858.1 - 5.4e-10 38.9 0.9 8.9e-10 38.3 0.0 1.7 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes LCCL PF03815.14 OAI99870.1 - 1.5e-16 60.1 0.0 2.7e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 LCCL domain DUF4579 PF15158.1 OAI99870.1 - 5.9 6.3 4.9 19 4.6 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4579) zf-BED PF02892.10 OAI99894.1 - 0.0052 16.5 1.6 0.0094 15.6 1.1 1.4 1 0 0 1 1 1 1 BED zinc finger zf-CCHC_6 PF15288.1 OAI99897.1 - 0.0058 16.2 0.5 0.018 14.7 0.4 1.8 1 0 0 1 1 1 1 Zinc knuckle ELFV_dehydrog_N PF02812.13 OAI99898.1 - 9.9e-17 60.7 0.0 1.8e-16 59.9 0.0 1.4 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Pkinase PF00069.20 OAI99913.1 - 1.8e-48 164.9 0.0 2.6e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI99913.1 - 2.3e-30 105.5 0.0 2.6e-29 102.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI99913.1 - 3e-06 26.4 0.0 5.8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 OAI99913.1 - 0.35 9.6 0.1 0.5 9.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Fumble PF03630.9 OAI99927.1 - 1.3e-108 362.9 0.0 2.3e-82 276.5 0.0 3.2 3 0 0 3 3 3 3 Fumble K_channel_TID PF07941.6 OAI99927.1 - 0.012 15.7 2.5 0.012 15.7 1.7 3.5 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain DNA_pol_phi PF04931.8 OAI99927.1 - 1.7 6.3 4.8 2.4 5.8 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2510 PF10708.4 OAI99960.1 - 0.015 14.7 0.6 0.064 12.7 0.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2510) AICARFT_IMPCHas PF01808.13 OAI99961.1 - 2.4e-06 26.8 0.0 2.7e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme DUF4611 PF15387.1 OAI99978.1 - 0.16 12.0 1.0 0.47 10.6 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) rve PF00665.21 OAI99994.1 - 1e-09 38.5 0.0 4.5e-09 36.4 0.0 2.2 1 1 1 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAI99994.1 - 3.6e-05 23.2 0.0 6.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 OAI99994.1 - 0.049 13.0 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger rve_3 PF13683.1 OAI99994.1 - 0.057 12.9 0.0 0.18 11.3 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain E1-E2_ATPase PF00122.15 OAJ00001.1 - 2.1e-51 174.1 2.6 3.2e-51 173.5 1.8 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 OAJ00001.1 - 5.3e-17 61.0 0.0 1e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2157 PF09925.4 OAJ00001.1 - 0.0066 16.0 2.5 0.082 12.5 0.0 2.5 2 1 0 2 2 2 1 Predicted membrane protein (DUF2157) Hydrolase PF00702.21 OAJ00001.1 - 0.032 14.6 0.2 0.072 13.4 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MARVEL PF01284.18 OAJ00001.1 - 0.046 13.5 4.0 0.058 13.2 0.4 2.3 2 0 0 2 2 2 0 Membrane-associating domain DUF202 PF02656.10 OAJ00001.1 - 1.2 9.3 4.8 11 6.2 0.5 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF1469 PF07332.6 OAJ00001.1 - 3.2 7.5 7.6 4.5 7.0 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) cNMP_binding PF00027.24 OAJ00043.1 - 1.3e-39 133.8 0.0 5.7e-20 70.9 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 OAJ00043.1 - 9.5e-13 47.3 0.2 1.8e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Phage_Cox PF10743.4 OAJ00044.1 - 0.0004 20.3 1.4 18 5.4 0.0 5.2 1 1 3 4 4 4 2 Regulatory phage protein cox DUF1247 PF06851.6 OAJ00060.1 - 0.1 12.2 0.2 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1247) Pkinase PF00069.20 OAJ00061.1 - 0.00063 18.9 0.0 0.00068 18.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Macoilin PF09726.4 OAJ00062.1 - 0.0093 14.3 12.0 0.012 13.9 8.3 1.1 1 0 0 1 1 1 1 Transmembrane protein GAGA_bind PF06217.7 OAJ00062.1 - 0.066 13.1 5.2 0.088 12.7 3.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.9 OAJ00062.1 - 0.9 7.4 13.3 1.2 7.1 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.1 OAJ00062.1 - 0.97 9.1 10.6 1.5 8.4 7.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A YqzE PF14038.1 OAJ00062.1 - 4.6 7.0 0.0 4.6 7.0 0.0 2.9 2 1 0 2 2 2 0 YqzE-like protein Nop14 PF04147.7 OAJ00062.1 - 7.7 4.3 16.1 9.9 3.9 11.1 1.1 1 0 0 1 1 1 0 Nop14-like family Phi-29_GP3 PF05435.6 OAJ00075.1 - 0.056 12.6 0.1 0.065 12.4 0.1 1.1 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 LIP PF03583.9 OAJ00093.1 - 9.6e-43 146.4 0.6 1.2e-40 139.5 0.4 2.0 1 1 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 OAJ00093.1 - 5.3e-10 39.5 0.0 6.9e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ00093.1 - 6e-08 32.5 0.0 1.1e-07 31.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 OAJ00093.1 - 0.024 14.3 0.1 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase Peptidase_S9 PF00326.16 OAJ00093.1 - 0.029 13.5 1.0 1.1 8.4 0.0 2.6 2 1 0 2 2 2 0 Prolyl oligopeptidase family F-box-like PF12937.2 OAJ00111.1 - 0.0017 18.0 0.5 0.089 12.5 0.1 2.9 2 0 0 2 2 2 2 F-box-like Pkinase PF00069.20 OAJ00127.1 - 0.0064 15.6 0.1 0.015 14.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Macoilin PF09726.4 OAJ00127.1 - 5.7 5.0 7.1 6.3 4.9 4.9 1.2 1 0 0 1 1 1 0 Transmembrane protein ParA PF10609.4 OAJ00128.1 - 5e-31 106.4 0.0 9.2e-31 105.5 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 OAJ00128.1 - 1.1e-10 41.2 0.0 2.8e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 OAJ00128.1 - 4.9e-06 26.5 0.0 0.00016 21.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 OAJ00128.1 - 0.00025 20.1 1.8 0.0014 17.6 0.3 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.1 OAJ00128.1 - 0.0004 19.8 0.0 0.00091 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 OAJ00128.1 - 0.0073 15.4 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MipZ PF09140.6 OAJ00128.1 - 0.025 13.6 0.0 0.55 9.2 0.0 2.1 1 1 0 2 2 2 0 ATPase MipZ AAA_26 PF13500.1 OAJ00128.1 - 0.026 14.1 0.1 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 OAJ00128.1 - 0.097 12.6 0.2 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 OAJ00128.1 - 0.14 12.3 0.0 0.44 10.7 0.0 1.8 2 0 0 2 2 2 0 RNA helicase RWD PF05773.17 OAJ00129.1 - 8.5e-07 28.8 1.0 1.5e-06 28.0 0.7 1.4 1 1 0 1 1 1 1 RWD domain PAT1 PF09770.4 OAJ00129.1 - 1.7 6.7 5.0 1.8 6.7 3.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-CCHC PF00098.18 OAJ00145.1 - 3e-32 108.9 46.9 2.6e-07 30.2 0.6 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ00145.1 - 1.2e-07 31.2 37.5 0.017 14.8 0.1 6.1 6 0 0 6 6 6 4 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ00145.1 - 7.6e-07 28.7 33.3 0.0074 15.9 0.2 6.0 3 2 3 6 6 6 4 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ00145.1 - 6.4e-06 25.5 35.8 0.0066 15.9 0.9 6.1 4 2 2 6 6 6 5 Zinc knuckle Mu-like_Com PF10122.4 OAJ00145.1 - 0.087 11.8 0.2 0.087 11.8 0.2 4.3 3 2 2 5 5 5 0 Mu-like prophage protein Com DZR PF12773.2 OAJ00145.1 - 7.2 6.5 35.9 6.8 6.6 2.2 4.4 2 1 0 2 2 2 0 Double zinc ribbon DnaJ_CXXCXGXG PF00684.14 OAJ00145.1 - 9 6.4 39.5 0.71 9.9 7.8 4.5 3 2 0 3 3 3 0 DnaJ central domain Abhydrolase_6 PF12697.2 OAJ00146.1 - 1.9e-13 50.8 0.2 1e-12 48.4 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ00146.1 - 0.00041 20.1 0.0 0.0069 16.1 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_10 PF05971.7 OAJ00153.1 - 9.8e-52 175.9 0.0 4.9e-31 107.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 OAJ00153.1 - 0.003 17.5 0.0 0.0088 16.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ00153.1 - 0.011 16.3 0.0 0.047 14.2 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ00153.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Mod_r PF07200.8 OAJ00154.1 - 7.7e-14 51.8 3.4 2.8e-10 40.3 1.9 2.1 2 0 0 2 2 2 2 Modifier of rudimentary (Mod(r)) protein Herpes_UL14 PF03580.9 OAJ00154.1 - 0.0022 17.8 1.6 0.0049 16.6 0.9 1.8 1 1 0 1 1 1 1 Herpesvirus UL14-like protein FlgN PF05130.7 OAJ00154.1 - 0.024 14.9 1.0 0.024 14.9 0.7 2.2 1 1 1 2 2 2 0 FlgN protein TraI_2 PF07514.6 OAJ00154.1 - 0.17 10.6 1.7 0.34 9.6 0.2 1.9 1 1 1 2 2 2 0 Putative helicase DUF972 PF06156.8 OAJ00154.1 - 0.33 11.3 1.7 0.89 9.9 0.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Abhydrolase_6 PF12697.2 OAJ00154.1 - 0.51 10.1 3.7 0.31 10.8 1.3 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family OPA3 PF07047.7 OAJ00156.1 - 1.4e-17 63.6 0.5 3e-17 62.6 0.3 1.6 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF2763 PF10961.3 OAJ00156.1 - 5.7 7.4 12.7 10 6.5 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) Histone_HNS PF00816.16 OAJ00156.1 - 8.6 6.9 8.4 1.9 9.0 1.4 2.3 2 0 0 2 2 2 0 H-NS histone family WEMBL PF05701.6 OAJ00187.1 - 0.00079 18.0 23.1 0.056 11.9 4.2 2.5 2 1 0 2 2 2 2 Weak chloroplast movement under blue light APG6 PF04111.7 OAJ00187.1 - 0.0033 16.5 0.8 0.0033 16.5 0.5 3.4 2 2 1 3 3 3 1 Autophagy protein Apg6 Cast PF10174.4 OAJ00187.1 - 0.33 8.9 28.5 0.17 9.9 7.4 2.6 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone Filament PF00038.16 OAJ00187.1 - 0.81 9.0 24.6 1.7 8.0 5.5 4.0 2 2 2 4 4 4 0 Intermediate filament protein Atg14 PF10186.4 OAJ00187.1 - 2.5 6.9 22.1 1.5 7.6 3.1 2.9 2 2 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MFS_1 PF07690.11 OAJ00203.1 - 3.8e-35 121.2 42.4 3.8e-35 121.2 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ00203.1 - 5.3e-06 25.2 24.1 0.00014 20.5 16.7 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Sec6 PF06046.8 OAJ00215.1 - 0.021 12.9 0.0 0.096 10.7 0.0 1.8 2 0 0 2 2 2 0 Exocyst complex component Sec6 AAA_32 PF13654.1 OAJ00215.1 - 0.059 12.0 0.0 0.096 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain GMC_oxred_C PF05199.8 OAJ00230.1 - 7.1e-32 110.6 0.1 1.7e-31 109.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 OAJ00230.1 - 3.3e-26 92.1 0.0 5.7e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 OAJ00230.1 - 0.019 15.0 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CheZ PF04344.8 OAJ00231.1 - 0.0003 20.5 0.8 0.00039 20.1 0.5 1.1 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ Cob_adeno_trans PF01923.13 OAJ00231.1 - 0.025 14.3 0.6 0.031 14.0 0.4 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Fib_alpha PF08702.5 OAJ00231.1 - 0.028 14.5 1.7 0.038 14.1 1.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3571 PF12095.3 OAJ00231.1 - 0.066 13.4 1.6 0.11 12.7 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3571) FliJ PF02050.11 OAJ00231.1 - 0.068 13.2 10.0 0.1 12.6 6.9 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein Med9 PF07544.8 OAJ00231.1 - 0.25 11.1 4.4 0.44 10.3 3.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 M_domain PF12938.2 OAJ00231.1 - 0.25 11.1 6.9 0.35 10.6 4.8 1.2 1 0 0 1 1 1 0 M domain of GW182 Rho_Binding PF08912.6 OAJ00231.1 - 7.2 6.9 8.4 19 5.6 0.8 2.3 1 1 1 2 2 2 0 Rho Binding F-box-like PF12937.2 OAJ00245.1 - 6.3e-15 54.6 0.8 1.8e-14 53.1 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ00245.1 - 3e-11 42.6 0.2 5.3e-11 41.8 0.2 1.4 1 0 0 1 1 1 1 F-box domain zf-C2HC5 PF06221.8 OAJ00261.1 - 4.6e-06 26.2 3.9 8.9e-06 25.3 2.7 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF2413 PF10310.4 OAJ00261.1 - 0.96 8.1 7.0 2.1 7.0 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Cactin_mid PF10312.4 OAJ00279.1 - 1.6e-60 203.6 4.3 1.6e-60 203.6 3.0 1.9 2 0 0 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.4 OAJ00279.1 - 4.1e-54 181.4 6.1 7.6e-54 180.6 4.2 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Homeobox_KN PF05920.6 OAJ00314.1 - 0.0016 18.0 0.0 0.0062 16.2 0.0 2.1 1 1 0 1 1 1 1 Homeobox KN domain Ustilago_mating PF05722.7 OAJ00314.1 - 0.019 14.2 0.2 0.019 14.2 0.1 3.2 3 1 0 3 3 3 0 Ustilago B locus mating-type protein Pyr_redox_3 PF13738.1 OAJ00335.1 - 4.7e-19 69.2 0.0 1.7e-17 64.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAJ00335.1 - 1.7e-09 36.4 0.0 2.2e-05 22.8 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAJ00335.1 - 1e-08 35.0 0.0 4.4e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAJ00335.1 - 3.3e-08 33.4 0.7 0.00056 19.7 0.2 3.6 3 1 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 OAJ00335.1 - 3e-06 26.3 0.0 0.00014 20.9 0.0 2.9 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 OAJ00335.1 - 6.1e-05 22.0 0.0 0.0043 15.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 OAJ00335.1 - 0.044 12.6 0.2 0.24 10.2 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 OAJ00335.1 - 0.13 11.1 0.0 9 5.0 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 OAJ00335.1 - 0.18 10.8 0.2 0.5 9.4 0.1 1.7 2 0 0 2 2 2 0 Thi4 family WD40 PF00400.27 OAJ00357.1 - 2.4e-20 71.5 0.4 7.9e-11 41.4 0.1 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 OAJ00357.1 - 0.00097 17.3 0.1 0.18 9.8 0.0 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Racemase_4 PF13615.1 OAJ00358.1 - 2.9e-15 56.3 0.0 8.6e-15 54.8 0.0 1.9 1 1 0 1 1 1 1 Putative alanine racemase MCM_bind PF09739.4 OAJ00358.1 - 4.3e-15 55.3 0.0 1.1e-13 50.8 0.0 2.3 1 1 0 1 1 1 1 Mini-chromosome maintenance replisome factor Hepar_II_III PF07940.8 OAJ00422.1 - 3.3e-10 39.9 1.7 1.4e-09 37.9 0.2 2.3 2 0 0 2 2 2 1 Heparinase II/III-like protein Methyltransf_PK PF05891.7 OAJ00465.1 - 3.8e-49 166.9 0.0 9.1e-16 57.8 0.0 4.2 3 1 0 3 3 3 3 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 OAJ00465.1 - 2.7e-05 23.9 0.0 0.00018 21.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ00465.1 - 0.00019 21.9 0.1 0.014 15.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ00465.1 - 0.00091 19.6 0.0 1.1 9.8 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ00465.1 - 0.027 14.8 0.0 7 7.0 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain MRVI1 PF05781.7 OAJ00465.1 - 0.041 12.2 1.4 0.083 11.2 0.0 1.9 2 0 0 2 2 2 0 MRVI1 protein Methyltransf_2 PF00891.13 OAJ00465.1 - 0.094 11.8 0.0 0.24 10.5 0.0 1.7 1 0 0 1 1 1 0 O-methyltransferase Metallothio_2 PF01439.13 OAJ00482.1 - 0.00061 20.2 4.5 0.046 14.2 0.8 2.4 2 0 0 2 2 2 2 Metallothionein DrsE_2 PF13686.1 OAJ00482.1 - 0.032 14.0 2.0 0.52 10.0 0.1 3.0 2 1 2 4 4 4 0 DsrE/DsrF/DrsH-like family Ring_hydroxyl_B PF00866.13 OAJ00482.1 - 0.056 13.1 0.0 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Ring hydroxylating beta subunit rve PF00665.21 OAJ00497.1 - 3.6e-14 52.8 0.0 9.4e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ00497.1 - 2.9e-06 26.7 0.0 6.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) KfrA_N PF11740.3 OAJ00497.1 - 0.23 11.9 8.3 0.99 9.8 0.8 2.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term AAA_13 PF13166.1 OAJ00552.1 - 0.0034 15.9 1.9 0.0037 15.8 1.3 1.0 1 0 0 1 1 1 1 AAA domain Spc7 PF08317.6 OAJ00552.1 - 0.0048 15.6 1.2 0.0058 15.3 0.8 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Atg14 PF10186.4 OAJ00552.1 - 0.0049 15.8 1.5 0.0061 15.5 1.1 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF3450 PF11932.3 OAJ00552.1 - 0.0051 16.1 0.0 0.0054 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) HOOK PF05622.7 OAJ00552.1 - 0.01 13.6 0.2 0.012 13.4 0.2 1.0 1 0 0 1 1 1 0 HOOK protein HAUS5 PF14817.1 OAJ00552.1 - 0.011 14.3 0.1 0.012 14.2 0.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Fez1 PF06818.10 OAJ00552.1 - 0.016 15.2 0.7 0.018 15.0 0.5 1.1 1 0 0 1 1 1 0 Fez1 ADIP PF11559.3 OAJ00552.1 - 0.023 14.6 1.7 0.028 14.3 1.2 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HrpB7 PF09486.5 OAJ00552.1 - 0.026 14.4 0.5 0.035 14.0 0.3 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) IncA PF04156.9 OAJ00552.1 - 0.04 13.5 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 OAJ00552.1 - 0.074 13.1 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FemAB PF02388.11 OAJ00552.1 - 0.077 11.6 1.3 0.096 11.3 0.9 1.1 1 0 0 1 1 1 0 FemAB family DUF1910 PF08928.5 OAJ00552.1 - 0.41 10.6 2.9 5.2 7.1 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1910) Med9 PF07544.8 OAJ00552.1 - 0.44 10.3 3.7 1.3 8.8 2.5 1.8 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.15 OAJ00552.1 - 0.44 10.3 3.6 3.5 7.4 2.0 1.9 1 1 1 2 2 2 0 Prefoldin subunit Lyase_aromatic PF00221.14 OAJ00553.1 - 0.00019 20.0 0.1 0.2 10.0 0.0 2.0 2 0 0 2 2 2 2 Aromatic amino acid lyase CRT10 PF08728.5 OAJ00572.1 - 5.2 4.9 19.9 8.5 4.2 13.8 1.3 1 0 0 1 1 1 0 CRT10 PLRV_ORF5 PF01690.12 OAJ00572.1 - 7.2 5.6 41.7 9.3 5.2 28.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein IBR PF01485.16 OAJ00573.1 - 9.1e-09 35.0 0.9 9.1e-09 35.0 0.6 3.8 2 1 2 4 4 4 1 IBR domain zf-RING_2 PF13639.1 OAJ00573.1 - 4.2e-08 32.8 15.1 6.5e-08 32.2 5.4 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ00573.1 - 6e-07 29.3 7.9 6e-07 29.3 5.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RWD PF05773.17 OAJ00573.1 - 9.8e-07 28.6 0.0 1.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_5 PF14634.1 OAJ00573.1 - 4.4e-05 23.1 7.2 4.4e-05 23.1 5.0 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 OAJ00573.1 - 6.7e-05 22.4 12.2 0.00012 21.6 4.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAJ00573.1 - 0.00024 20.7 2.8 0.00024 20.7 1.9 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 OAJ00573.1 - 0.0042 16.8 6.0 0.03 14.1 4.2 2.3 1 1 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 OAJ00573.1 - 0.11 12.4 12.9 0.26 11.2 3.7 3.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 OAJ00573.1 - 0.71 9.5 15.5 0.14 11.7 1.0 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain UPF0547 PF10571.4 OAJ00573.1 - 0.8 9.4 5.5 2.6 7.7 0.0 3.3 2 1 1 3 3 3 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.1 OAJ00573.1 - 4.3 6.6 10.1 7.5 5.8 2.5 4.0 3 1 0 3 3 3 0 zinc-ribbon domain FYVE PF01363.16 OAJ00573.1 - 9.6 6.1 17.5 7.9 6.4 4.5 3.1 2 1 1 3 3 3 0 FYVE zinc finger DUF3735 PF12537.3 OAJ00590.1 - 0.039 13.9 0.0 0.093 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) Pkinase PF00069.20 OAJ00606.1 - 4.8e-21 75.0 0.0 9.2e-21 74.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ00606.1 - 3.6e-11 42.6 0.0 5.4e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ00606.1 - 8.5e-09 34.7 0.0 1.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 OAJ00606.1 - 0.014 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 OAJ00606.1 - 0.072 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HpaP PF09483.5 OAJ00629.1 - 4.6 7.1 15.5 5.6 6.8 10.8 1.1 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Zn_protease PF05618.6 OAJ00630.1 - 0.024 14.3 0.1 0.027 14.1 0.1 1.1 1 0 0 1 1 1 0 Putative ATP-dependant zinc protease MFS_1 PF07690.11 OAJ00654.1 - 1.6e-17 63.2 36.4 1.6e-17 63.2 25.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ00654.1 - 0.003 16.2 16.1 0.003 16.2 11.2 3.0 2 2 1 3 3 3 1 Sugar (and other) transporter CRT-like PF08627.5 OAJ00654.1 - 0.056 13.3 2.6 1.4 8.8 0.1 2.9 3 0 0 3 3 3 0 CRT-like PT PF04886.7 OAJ00655.1 - 0.91 8.8 6.5 1.2 8.5 0.7 2.2 1 1 1 2 2 2 0 PT repeat RVT_2 PF07727.9 OAJ00670.1 - 2.6e-86 288.6 0.0 3.5e-86 288.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ00670.1 - 5.4e-21 74.9 0.0 1.1e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ00670.1 - 0.00046 19.6 0.9 0.01 15.3 0.4 3.1 2 1 0 2 2 2 1 Integrase core domain Rifin_STEVOR PF02009.11 OAJ00710.1 - 0.012 15.2 0.2 0.014 15.0 0.2 1.1 1 0 0 1 1 1 0 Rifin/stevor family MCPVI PF02993.9 OAJ00710.1 - 0.031 14.4 8.9 0.04 14.0 6.1 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Trypan_PARP PF05887.6 OAJ00710.1 - 0.036 13.8 0.2 0.052 13.3 0.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Raftlin PF15250.1 OAJ00710.1 - 0.055 11.9 3.4 0.071 11.6 2.3 1.1 1 0 0 1 1 1 0 Raftlin BRF1 PF07741.8 OAJ00710.1 - 0.058 13.6 6.2 0.12 12.6 3.4 1.9 2 0 0 2 2 2 0 Brf1-like TBP-binding domain NARP1 PF12569.3 OAJ00710.1 - 0.17 10.6 5.0 0.21 10.2 3.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PAT1 PF09770.4 OAJ00710.1 - 0.57 8.3 17.1 0.64 8.1 11.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ERF PF04404.7 OAJ00710.1 - 0.64 9.5 10.0 1 8.8 6.9 1.2 1 0 0 1 1 1 0 ERF superfamily DUF4557 PF15101.1 OAJ00710.1 - 0.99 9.2 7.4 1.5 8.6 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Het-C PF07217.6 OAJ00710.1 - 3.5 5.6 5.3 4.2 5.4 0.0 2.0 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C G0-G1_switch_2 PF15103.1 OAJ00710.1 - 5.8 7.1 6.8 12 6.1 4.7 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF4175 PF13779.1 OAJ00710.1 - 7.3 4.1 17.0 9.4 3.7 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Peptidase_S49_N PF08496.5 OAJ00710.1 - 9.4 6.0 7.0 14 5.4 4.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HLH PF00010.21 OAJ00733.1 - 0.00011 21.8 0.0 0.018 14.7 0.4 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain SPX PF03105.14 OAJ00733.1 - 0.0026 17.5 4.1 0.0026 17.5 2.8 2.0 2 0 0 2 2 2 1 SPX domain DUF4407 PF14362.1 OAJ00733.1 - 0.09 11.7 3.5 0.18 10.6 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Raftlin PF15250.1 OAJ00733.1 - 1.4 7.3 12.4 2.6 6.4 8.6 1.3 1 0 0 1 1 1 0 Raftlin Otopetrin PF03189.8 OAJ00733.1 - 2.7 6.9 5.7 0.26 10.2 0.1 1.8 2 0 0 2 2 2 0 Otopetrin Band_3_cyto PF07565.8 OAJ00733.1 - 5.8 6.3 15.7 1.5 8.2 5.6 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Thioredoxin PF00085.15 OAJ00751.1 - 5.7e-34 115.9 0.0 9.1e-22 76.7 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 OAJ00751.1 - 5.3e-12 45.9 0.0 0.007 16.1 0.0 3.9 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 OAJ00751.1 - 9.9e-08 32.1 0.9 0.00093 19.3 0.2 3.9 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_3 PF13192.1 OAJ00751.1 - 8e-06 25.5 0.0 0.0027 17.4 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_8 PF13905.1 OAJ00751.1 - 0.0012 18.8 0.1 0.01 15.9 0.1 2.5 2 1 1 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 OAJ00751.1 - 0.01 15.5 0.0 0.038 13.6 0.0 2.1 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 OAJ00751.1 - 0.037 13.5 0.1 0.35 10.4 0.0 2.4 2 0 0 2 2 2 0 Redoxin Thioredoxin_4 PF13462.1 OAJ00751.1 - 0.088 12.8 0.5 0.55 10.2 0.2 2.2 2 0 0 2 2 2 0 Thioredoxin R3H PF01424.17 OAJ00776.1 - 8.9e-12 44.5 0.0 2.4e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 R3H domain Myb_DNA-bind_3 PF12776.2 OAJ00796.1 - 4.7e-12 46.3 0.2 8.2e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ00796.1 - 0.00023 21.2 0.0 0.00061 19.8 0.0 1.8 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain TMEM247 PF15444.1 OAJ00796.1 - 0.48 10.2 2.0 0.26 11.0 0.1 1.5 2 0 0 2 2 2 0 Transmembrane protein 247 CwfJ_C_1 PF04677.10 OAJ00812.1 - 1.8e-26 92.1 0.0 2.5e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 OAJ00812.1 - 1.7e-22 79.7 0.1 3.5e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DDE_Tnp_4 PF13359.1 OAJ00835.1 - 4.9e-26 91.2 0.0 6.2e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ00835.1 - 6.8e-11 41.9 0.0 2.7e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 Plant transposon protein DDE_Tnp_1 PF01609.16 OAJ00835.1 - 8e-08 32.0 0.1 0.0093 15.5 0.0 2.2 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.1 OAJ00835.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.2 OAJ00836.1 - 5.6e-14 52.5 1.6 5.6e-14 52.5 1.1 2.5 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ00836.1 - 8.3e-07 29.0 0.8 2.4e-06 27.5 0.6 1.9 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 OAJ00836.1 - 0.029 14.2 0.1 0.13 12.1 0.1 2.1 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ00836.1 - 0.042 13.9 0.2 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain FHA PF00498.21 OAJ00858.1 - 0.052 13.6 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 FHA domain UQ_con PF00179.21 OAJ00906.1 - 1.4e-49 167.1 0.0 1.6e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ00906.1 - 1.8e-07 30.9 0.0 5.2e-07 29.4 0.0 1.7 1 1 1 2 2 2 1 Prokaryotic E2 family B FYVE PF01363.16 OAJ00907.1 - 9.8e-19 67.0 0.0 2.2e-18 65.9 0.0 1.6 1 1 0 1 1 1 1 FYVE zinc finger TerY-C PF15616.1 OAJ00907.1 - 0.0076 16.1 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 TerY-C metal binding domain zf-DHHC PF01529.15 OAJ00907.1 - 0.11 11.9 0.9 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase DZR PF12773.2 OAJ00907.1 - 0.79 9.5 4.1 1.1 9.1 1.1 2.1 2 0 0 2 2 2 0 Double zinc ribbon UPF0547 PF10571.4 OAJ00907.1 - 6.8 6.4 6.3 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DDE_Tnp_4 PF13359.1 OAJ00928.1 - 3.3e-21 75.5 0.0 4e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 OAJ00928.1 - 9.9e-06 25.2 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain U3snoRNP10 PF12397.3 OAJ00991.1 - 6.7e-06 26.0 0.7 1.8e-05 24.6 0.5 1.8 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 10 RVT_1 PF00078.22 OAJ01020.1 - 2.5e-19 69.5 0.0 4.8e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ01020.1 - 6.2e-14 52.1 0.0 1.3e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain WD40 PF00400.27 OAJ01043.1 - 1.8e-38 129.0 8.5 1.3e-08 34.4 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Sof1 PF04158.9 OAJ01043.1 - 2.1e-24 85.3 11.2 3.2e-24 84.7 7.8 1.3 1 0 0 1 1 1 1 Sof1-like domain Nucleoporin_N PF08801.6 OAJ01043.1 - 0.0041 15.9 0.1 1.5 7.4 0.0 3.1 2 2 0 4 4 4 2 Nup133 N terminal like Me-amine-dh_H PF06433.6 OAJ01043.1 - 0.037 12.6 0.0 0.053 12.1 0.0 1.2 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) DSBA PF01323.15 OAJ01044.1 - 0.015 14.8 0.2 0.036 13.6 0.1 1.6 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Pyr_redox_2 PF07992.9 OAJ01063.1 - 1.2e-26 93.8 0.1 9.9e-17 61.4 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ01063.1 - 6.3e-12 45.7 0.1 8.5e-11 42.1 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAJ01063.1 - 0.0013 18.7 0.1 0.15 12.0 0.0 3.3 3 2 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ01063.1 - 0.24 10.2 4.2 0.62 8.9 0.0 3.0 2 2 2 4 4 4 0 FAD dependent oxidoreductase Spore_YtfJ PF09579.5 OAJ01083.1 - 2.6 7.9 14.5 0.93 9.3 3.7 2.8 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) MIP-T3 PF10243.4 OAJ01106.1 - 0.81 8.0 5.9 0.89 7.9 4.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 zf-C3HC4_3 PF13920.1 OAJ01107.1 - 0.048 13.3 3.1 0.092 12.4 2.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cyt-b5 PF00173.23 OAJ01172.1 - 7.7e-09 35.2 0.0 1.1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TAP35_44 PF07265.6 OAJ01172.1 - 0.064 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 HECT PF00632.20 OAJ01173.1 - 5.1e-92 308.4 0.0 5.9e-92 308.1 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AMP-binding PF00501.23 OAJ01192.1 - 2.5e-21 75.5 0.7 2.4e-19 69.0 0.5 2.5 2 1 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.7 OAJ01192.1 - 1.2e-13 50.5 0.0 2.4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 OAJ01192.1 - 1.4e-06 27.8 0.0 3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 OAJ01192.1 - 5.1e-06 26.5 0.2 4.9e-05 23.3 0.1 2.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ01192.1 - 0.00063 19.4 0.1 0.0055 16.3 0.0 2.6 2 1 0 2 2 2 1 KR domain PP-binding PF00550.20 OAJ01192.1 - 0.019 15.2 0.0 0.16 12.2 0.0 2.3 1 1 0 1 1 1 0 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 OAJ01192.1 - 0.14 10.9 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ran_BP1 PF00638.13 OAJ01194.1 - 4.3e-51 172.0 2.0 7.3e-51 171.3 1.4 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 OAJ01194.1 - 4.5e-06 26.3 1.0 2.5e-05 23.9 0.7 1.9 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.9 OAJ01194.1 - 0.0002 20.9 0.7 0.00026 20.5 0.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) FctA PF12892.2 OAJ01194.1 - 0.27 12.0 4.9 0.32 11.8 0.2 2.9 2 1 1 3 3 3 0 T surface-antigen of pili ASFV_J13L PF05568.6 OAJ01194.1 - 0.91 9.0 5.1 1.4 8.4 3.5 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein APG12 PF04110.8 OAJ01195.1 - 5.7e-32 109.7 0.0 7.2e-32 109.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 OAJ01195.1 - 0.004 17.1 0.0 0.0047 16.8 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like FliP PF00813.15 OAJ01195.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 FliP family rve PF00665.21 OAJ01216.1 - 1.6e-22 79.8 0.0 3.8e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 OAJ01216.1 - 3.4e-06 26.7 3.0 3.4e-06 26.7 2.1 1.9 2 0 0 2 2 2 1 Zinc knuckle gag_pre-integrs PF13976.1 OAJ01216.1 - 1.2e-05 24.8 0.1 3.1e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ01216.1 - 0.0045 16.4 0.5 0.036 13.6 0.4 2.4 1 1 0 1 1 1 1 Integrase core domain KH_1 PF00013.24 OAJ01237.1 - 1e-08 34.6 0.0 6.6e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 OAJ01237.1 - 7.3e-05 22.3 0.8 0.0031 17.1 0.0 2.5 2 0 0 2 2 2 1 KH domain Trp_repressor PF01371.14 OAJ01237.1 - 0.04 13.8 0.1 0.089 12.7 0.1 1.5 1 0 0 1 1 1 0 Trp repressor protein RAP1 PF07218.6 OAJ01258.1 - 4.6 5.2 10.7 4.8 5.1 7.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Asp PF00026.18 OAJ01299.1 - 2.7e-42 145.1 0.0 8.1e-42 143.5 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 OAJ01299.1 - 0.00069 20.0 0.3 0.039 14.4 0.1 2.5 2 0 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.1 OAJ01299.1 - 0.00073 19.5 1.8 0.0064 16.4 1.3 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Acyl-CoA_dh_1 PF00441.19 OAJ01323.1 - 4.6e-49 166.3 5.8 4.6e-49 166.3 4.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ01323.1 - 6.4e-25 86.4 0.4 2e-24 84.8 0.3 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 OAJ01323.1 - 1.3e-24 86.9 0.2 1.3e-24 86.9 0.2 2.6 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAJ01323.1 - 1.3e-18 67.5 5.8 1.3e-18 67.5 4.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 OAJ01323.1 - 1.3e-05 24.7 0.2 5.4e-05 22.7 0.1 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Ras PF00071.17 OAJ01351.1 - 1.1e-56 190.6 0.0 1.4e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ01351.1 - 1.7e-19 70.4 0.0 2.5e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ01351.1 - 9.9e-17 60.7 0.0 8.7e-16 57.6 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ01351.1 - 2.6e-07 30.0 0.0 3.4e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 OAJ01351.1 - 3.1e-05 23.4 0.0 4.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ01351.1 - 0.0014 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 OAJ01351.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ATP-synt_10 PF05176.9 OAJ01352.1 - 1.4e-47 162.0 0.0 4.3e-31 108.0 0.0 2.1 2 0 0 2 2 2 2 ATP10 protein Abhydrolase_6 PF12697.2 OAJ01352.1 - 0.073 12.9 2.6 0.11 12.3 0.8 2.0 2 1 0 2 2 2 0 Alpha/beta hydrolase family CKS PF01111.14 OAJ01353.1 - 3.1e-35 119.8 0.1 4.1e-35 119.4 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Lipase_3 PF01764.20 OAJ01375.1 - 1.4e-16 60.4 0.0 2.1e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.8 OAJ01375.1 - 0.021 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ01375.1 - 0.058 13.1 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_45 PF02015.11 OAJ01376.1 - 2.6e-22 79.8 0.6 3.1e-22 79.6 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 HSP33 PF01430.14 OAJ01400.1 - 0.16 11.0 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Hsp33 protein DUF202 PF02656.10 OAJ01401.1 - 0.049 13.8 0.6 0.11 12.7 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF202) FA_hydroxylase PF04116.8 OAJ01427.1 - 1.1e-12 48.3 9.6 1.1e-12 48.3 6.6 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MULE PF10551.4 OAJ01444.1 - 2e-09 37.4 0.3 4.4e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 OAJ01444.1 - 0.0002 20.0 0.1 0.00025 19.7 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family zf-CCHC PF00098.18 OAJ01470.1 - 0.0043 16.9 6.0 0.0075 16.1 4.2 1.4 1 0 0 1 1 1 1 Zinc knuckle GrpE PF01025.14 OAJ01470.1 - 0.81 9.2 4.0 1.1 8.8 1.6 1.8 2 0 0 2 2 2 0 GrpE Thaumatin PF00314.12 OAJ01494.1 - 4.5e-19 68.7 4.4 1.1e-18 67.4 3.1 1.6 1 1 0 1 1 1 1 Thaumatin family FAD_binding_4 PF01565.18 OAJ01515.1 - 1.5e-27 95.7 1.6 2.8e-27 94.8 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAJ01515.1 - 1.7e-06 27.8 0.1 3.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF3357 PF11837.3 OAJ01515.1 - 0.032 14.0 0.5 0.075 12.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) NLBH PF05211.7 OAJ01515.1 - 0.23 10.6 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) Fringe PF02434.11 OAJ01536.1 - 2.2e-05 23.8 0.7 0.00021 20.6 0.3 2.3 2 1 0 2 2 2 1 Fringe-like Phage_integrase PF00589.17 OAJ01537.1 - 0.0028 17.3 0.0 0.0045 16.6 0.0 1.4 1 1 0 1 1 1 1 Phage integrase family Cu-oxidase_3 PF07732.10 OAJ01562.1 - 5.5e-28 97.0 3.3 1.1e-26 92.8 0.1 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 OAJ01562.1 - 3.2e-15 56.3 0.0 6.7e-14 52.0 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAJ01562.1 - 1e-14 54.1 9.9 3.4e-11 42.8 2.5 3.5 2 2 0 2 2 2 2 Multicopper oxidase Histone PF00125.19 OAJ01587.1 - 9.9e-11 41.6 0.7 1.4e-10 41.0 0.1 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 BON PF04972.12 OAJ01587.1 - 0.019 14.6 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 BON domain zf-BED PF02892.10 OAJ01588.1 - 0.001 18.7 0.4 0.001 18.7 0.3 2.0 2 0 0 2 2 2 1 BED zinc finger zf-C2H2 PF00096.21 OAJ01588.1 - 0.073 13.4 0.7 0.22 11.9 0.5 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type PRCC PF10253.4 OAJ01588.1 - 1.2 9.8 6.6 1.3 9.6 3.0 2.1 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Med3 PF11593.3 OAJ01588.1 - 5.8 6.0 11.1 10 5.2 7.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CH PF00307.26 OAJ01608.1 - 1.1e-66 221.6 0.0 1.6e-17 63.5 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 OAJ01608.1 - 2.3e-06 27.1 0.0 1.4 8.6 0.0 4.1 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_7 PF13499.1 OAJ01608.1 - 0.0018 18.4 0.9 0.005 16.9 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 OAJ01608.1 - 0.036 13.3 1.3 0.65 9.4 0.0 3.2 3 0 0 3 3 3 0 EF hand DUF1509 PF07420.6 OAJ01625.1 - 0.16 11.2 4.5 0.18 11.0 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) UPF0506 PF11703.3 OAJ01648.1 - 0.06 13.3 6.8 3 7.8 1.5 2.4 2 0 0 2 2 2 0 UPF0506 Omega-toxin PF06357.6 OAJ01648.1 - 1.2 8.7 14.1 2.7 7.6 3.4 2.5 1 1 1 2 2 2 0 Omega-atracotoxin EB PF01683.13 OAJ01648.1 - 1.4 9.0 9.7 4.1 7.5 6.7 1.8 1 1 0 1 1 1 0 EB module Colipase-like PF15083.1 OAJ01648.1 - 1.8 8.5 4.9 43 4.1 3.2 2.3 1 1 0 1 1 1 0 Colipase-like CCDC84 PF14968.1 OAJ01648.1 - 3.6 7.0 7.8 3.9 6.8 5.4 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 TFIIA PF03153.8 OAJ01648.1 - 3.8 7.3 15.1 4.2 7.1 10.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 OAJ01648.1 - 5 6.4 19.2 5.1 6.3 13.3 1.0 1 0 0 1 1 1 0 Vta1 like AUX_IAA PF02309.11 OAJ01648.1 - 6 6.5 8.9 6.5 6.4 6.2 1.2 1 0 0 1 1 1 0 AUX/IAA family rve PF00665.21 OAJ01673.1 - 7.2e-05 22.8 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_Crp_2 PF13545.1 OAJ01673.1 - 0.027 14.2 0.4 0.086 12.6 0.1 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Trp_repressor PF01371.14 OAJ01673.1 - 0.051 13.4 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 Trp repressor protein DDRGK PF09756.4 OAJ01674.1 - 0.68 9.3 8.0 0.8 9.0 5.5 1.1 1 0 0 1 1 1 0 DDRGK domain Nop14 PF04147.7 OAJ01674.1 - 4.6 5.0 13.0 3.5 5.4 7.4 1.6 1 1 0 2 2 2 0 Nop14-like family COesterase PF00135.23 OAJ01744.1 - 2e-58 198.4 0.0 6.4e-58 196.7 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ01744.1 - 3.2e-11 43.1 0.2 1.8e-10 40.7 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 OAJ01744.1 - 0.00063 19.0 0.1 0.0014 17.8 0.1 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 OAJ01744.1 - 0.0084 15.8 0.6 0.02 14.6 0.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DcpS_C PF11969.3 OAJ01744.1 - 0.0087 16.2 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 OAJ01744.1 - 0.039 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 HIT domain Esterase PF00756.15 OAJ01744.1 - 0.057 12.8 0.2 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 OAJ01744.1 - 0.15 11.2 0.1 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Collagen PF01391.13 OAJ01769.1 - 3.8e-15 55.1 60.5 2.1e-09 36.7 19.7 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) PIF1 PF05970.9 OAJ01787.1 - 2.8e-53 181.1 0.0 3.7e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ01787.1 - 5.5e-05 22.8 0.0 0.00014 21.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Brr6_like_C_C PF10104.4 OAJ01821.1 - 0.028 13.9 1.6 0.046 13.2 1.0 1.5 1 1 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain PetN PF03742.9 OAJ01821.1 - 0.099 12.2 0.2 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 PetN NolV PF06635.7 OAJ01849.1 - 0.12 11.5 0.1 0.39 9.8 0.0 1.8 2 0 0 2 2 2 0 Nodulation protein NolV Tachystatin_B PF11478.3 OAJ01894.1 - 0.3 10.8 4.5 0.79 9.4 3.1 1.7 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B RTC4 PF14474.1 OAJ01916.1 - 0.024 14.5 0.0 0.061 13.2 0.0 1.7 1 1 0 1 1 1 0 RTC4-like domain zf-HC2 PF13490.1 OAJ01916.1 - 0.15 12.0 0.7 0.29 11.1 0.1 1.8 2 0 0 2 2 2 0 Putative zinc-finger ATP-synt_D PF01813.12 OAJ01941.1 - 0.036 13.6 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 ATP synthase subunit D Sec23_helical PF04815.10 OAJ01994.1 - 5.5e-25 86.7 0.5 1e-24 85.9 0.4 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 OAJ01994.1 - 8.4e-09 35.0 0.0 2.4e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat DUF3429 PF11911.3 OAJ01995.1 - 6.1e-38 130.0 16.1 8.4e-38 129.5 11.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) RVT_1 PF00078.22 OAJ02022.1 - 8.9e-20 70.9 0.0 1.6e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ02022.1 - 2.3e-15 56.7 0.0 5.5e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ02023.1 - 3.5e-05 24.2 0.1 6.5e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ02023.1 - 0.0005 19.9 0.0 0.0013 18.6 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ02023.1 - 0.0029 17.3 0.1 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease MDMPI_C PF07398.6 OAJ02023.1 - 0.35 11.4 3.6 0.17 12.5 0.5 2.0 2 0 0 2 2 2 0 MDMPI C-terminal domain adh_short PF00106.20 OAJ02025.1 - 0.02 14.7 0.1 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase DS PF01916.12 OAJ02026.1 - 1.8e-134 447.5 0.0 2.1e-134 447.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF1168 PF06658.7 OAJ02046.1 - 4.3e-39 133.2 12.8 8e-39 132.3 8.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF3043 PF11241.3 OAJ02046.1 - 0.51 9.9 4.9 0.68 9.4 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DDHD PF02862.12 OAJ02046.1 - 3.2 7.4 6.4 4.8 6.9 4.5 1.2 1 0 0 1 1 1 0 DDHD domain Sec62 PF03839.11 OAJ02046.1 - 4.9 6.5 6.3 6.8 6.0 4.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 RAMP4 PF06624.7 OAJ02047.1 - 0.00011 21.6 4.7 0.00035 20.0 3.3 1.8 1 1 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF4366 PF14283.1 OAJ02047.1 - 0.031 13.7 0.0 0.036 13.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) UQ_con PF00179.21 OAJ02048.1 - 1.9e-44 150.5 0.0 2.2e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Helicase_C PF00271.26 OAJ02078.1 - 1.3e-11 44.1 0.2 1.4e-10 40.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ02078.1 - 0.00019 20.9 0.0 0.00067 19.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase PBP1_TM PF14812.1 OAJ02078.1 - 5.1 7.4 10.3 5.4 7.4 5.7 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BRCT PF00533.21 OAJ02131.1 - 1.1e-09 38.2 0.3 7.5e-09 35.6 0.1 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 OAJ02131.1 - 0.00051 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain DCX PF03607.12 OAJ02131.1 - 0.035 13.6 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 Doublecortin TGF_beta_GS PF08515.7 OAJ02131.1 - 0.09 12.1 0.9 0.27 10.5 0.6 1.8 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif adh_short PF00106.20 OAJ02132.1 - 1.1e-14 54.7 0.8 2e-14 53.8 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAJ02132.1 - 1.2e-08 34.8 0.1 2.4e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ02132.1 - 8.7e-05 22.3 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 OAJ02132.1 - 0.042 12.7 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein WW PF00397.21 OAJ02157.1 - 4.1e-08 32.9 1.6 0.0015 18.3 0.1 2.5 2 0 0 2 2 2 2 WW domain TBX PF12598.3 OAJ02187.1 - 0.072 13.4 2.4 0.084 13.2 1.6 1.1 1 0 0 1 1 1 0 T-box transcription factor Zn_protease PF05618.6 OAJ02189.1 - 0.0092 15.6 0.2 0.011 15.4 0.2 1.1 1 0 0 1 1 1 1 Putative ATP-dependant zinc protease Herpes_ICP4_N PF03584.10 OAJ02189.1 - 0.056 12.9 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region PSRT PF07636.6 OAJ02189.1 - 2.5 7.6 5.5 1.7 8.1 2.3 1.9 1 1 0 1 1 1 0 PSRT CDC45 PF02724.9 OAJ02252.1 - 0.00044 18.4 6.8 0.00055 18.1 4.7 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 OAJ02252.1 - 0.014 13.3 13.0 0.017 13.0 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 OAJ02252.1 - 0.028 14.0 8.8 0.045 13.3 6.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.7 OAJ02252.1 - 0.061 12.5 9.9 0.095 11.9 6.9 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 OAJ02252.1 - 0.26 10.3 12.7 0.44 9.5 8.8 1.3 1 0 0 1 1 1 0 BUD22 Paf1 PF03985.8 OAJ02252.1 - 0.94 8.1 12.9 1.5 7.4 8.9 1.2 1 0 0 1 1 1 0 Paf1 Vfa1 PF08432.5 OAJ02252.1 - 1.6 8.6 8.3 3.3 7.6 5.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TLP-20 PF06088.6 OAJ02252.1 - 1.7 8.3 5.9 3.8 7.1 4.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAM176 PF14851.1 OAJ02252.1 - 2.1 8.0 6.3 4.5 6.9 4.4 1.5 1 0 0 1 1 1 0 FAM176 family Ldh_1_C PF02866.13 OAJ02287.1 - 6.5e-07 29.2 0.0 1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_45 PF02015.11 OAJ02317.1 - 2.1e-48 165.1 4.7 2.5e-48 164.8 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 HsbA PF12296.3 OAJ02320.1 - 2e-13 50.2 12.1 3e-13 49.7 8.4 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A FUN14 PF04930.10 OAJ02320.1 - 0.076 13.3 2.6 0.19 12.0 1.8 2.0 1 1 0 1 1 1 0 FUN14 family Baculo_PEP_C PF04513.7 OAJ02320.1 - 1.9 8.3 9.1 3.8 7.3 6.1 1.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SNF2_N PF00176.18 OAJ02345.1 - 4.6e-27 94.5 0.0 7.2e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2019 PF09450.5 OAJ02345.1 - 0.027 14.3 0.1 0.069 13.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) Aida_N PF08910.5 OAJ02345.1 - 0.053 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Aida N-terminus Aa_trans PF01490.13 OAJ02374.1 - 2.4e-86 289.8 5.3 3e-86 289.4 3.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RVT_1 PF00078.22 OAJ02424.1 - 2.7e-17 62.8 0.0 8.5e-17 61.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 OAJ02424.1 - 0.36 10.8 4.1 0.75 9.8 2.8 1.6 1 0 0 1 1 1 0 Zinc knuckle Pterin_bind PF00809.17 OAJ02454.1 - 5.3e-50 169.7 0.0 1.5e-49 168.2 0.0 1.8 1 1 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 OAJ02454.1 - 1.3e-27 96.0 0.1 3.3e-24 85.0 0.0 2.5 1 1 0 2 2 2 2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 OAJ02454.1 - 1.9e-21 76.3 0.0 3.9e-12 46.3 0.0 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase Rap1_C PF11626.3 OAJ02454.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Asparaginase PF00710.15 OAJ02482.1 - 9.4e-126 418.9 0.0 1.2e-125 418.5 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 OAJ02482.1 - 6.4e-12 45.6 0.0 1.4e-11 44.5 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ02482.1 - 2.7e-11 42.6 0.9 1.6e-05 24.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 OAJ02482.1 - 3.7e-10 40.0 0.2 2.1e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ02482.1 - 5.4e-10 38.5 1.6 1.8e-05 24.4 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 OAJ02482.1 - 3.2e-08 33.5 0.5 0.00017 21.7 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) RFamide_26RFa PF11109.3 OAJ02508.1 - 0.13 12.1 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 DUF4413 PF14372.1 OAJ02565.1 - 0.002 18.0 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) DUF1146 PF06612.6 OAJ02565.1 - 0.04 13.8 0.1 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1146) SDA1 PF05285.7 OAJ02565.1 - 2.8 7.1 13.0 0.39 9.9 5.5 1.8 2 0 0 2 2 2 0 SDA1 ATE_N PF04376.8 OAJ02570.1 - 0.05 13.4 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, N terminus GATase_4 PF13230.1 OAJ02655.1 - 7.5e-19 67.4 0.0 2.2e-18 65.9 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 OAJ02655.1 - 9.4e-10 38.5 0.0 4.2e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 OAJ02655.1 - 4.6e-08 32.1 0.1 5.5e-07 28.6 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferases class-II DUF1454 PF07305.7 OAJ02655.1 - 0.077 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) Asp PF00026.18 OAJ02658.1 - 2.1e-37 129.0 0.0 3.6e-37 128.3 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ02658.1 - 3.9e-07 30.1 0.3 9.8e-07 28.8 0.1 1.7 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal RVT_1 PF00078.22 OAJ02689.1 - 3.8e-17 62.3 0.0 6.7e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fringe PF02434.11 OAJ02712.1 - 5.9e-06 25.6 0.2 1.4e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 OAJ02712.1 - 0.066 12.7 0.0 1.3 8.5 0.0 2.2 1 1 0 1 1 1 0 Galactosyltransferase DUF4328 PF14219.1 OAJ02742.1 - 0.027 13.7 0.2 0.082 12.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) zf-RING_4 PF14570.1 OAJ02742.1 - 0.17 11.5 3.1 0.41 10.2 2.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DDE_3 PF13358.1 OAJ02804.1 - 8.7e-33 113.1 0.0 2.1e-32 111.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 OAJ02804.1 - 1.7e-06 27.9 0.0 5.7e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 OAJ02804.1 - 6.8e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 OAJ02804.1 - 0.00019 21.3 0.0 0.00045 20.1 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain DDE_1 PF03184.14 OAJ02804.1 - 0.00049 19.2 0.0 0.00081 18.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAJ02804.1 - 0.00089 20.0 0.0 0.0032 18.2 0.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 OAJ02804.1 - 0.00095 18.2 0.1 0.047 12.8 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 rve PF00665.21 OAJ02804.1 - 0.0043 17.1 0.0 0.015 15.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_33 PF13592.1 OAJ02804.1 - 0.024 14.1 0.0 0.083 12.4 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix HTH_11 PF08279.7 OAJ02804.1 - 0.06 12.9 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 HTH domain MULE PF10551.4 OAJ02838.1 - 3.5e-12 46.3 0.1 9.7e-12 44.9 0.0 1.7 2 0 0 2 2 2 1 MULE transposase domain rve PF00665.21 OAJ02866.1 - 8.3e-17 61.4 0.0 5.7e-16 58.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain p450 PF00067.17 OAJ02867.1 - 4.2e-15 55.2 0.0 5.2e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2236 PF09995.4 OAJ02897.1 - 1.9e-21 76.4 0.3 5.2e-20 71.7 0.0 3.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) RVP PF00077.15 OAJ02931.1 - 0.0011 18.8 0.0 0.0056 16.5 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAJ02931.1 - 0.0013 19.1 0.1 0.0038 17.7 0.0 1.8 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ02931.1 - 0.1 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Tim54 PF11711.3 OAJ02955.1 - 0.16 10.5 0.1 0.2 10.2 0.0 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PAT1 PF09770.4 OAJ02955.1 - 9.1 4.3 6.1 10 4.1 4.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ABC1 PF03109.11 OAJ03015.1 - 7.4e-26 90.4 0.0 1.5e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Oxidored-like PF09791.4 OAJ03015.1 - 6.8e-18 63.8 1.5 1.7e-17 62.5 1.0 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal gag_pre-integrs PF13976.1 OAJ03047.1 - 5.6e-07 29.1 0.0 1.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain RVP PF00077.15 OAJ03047.1 - 0.0063 16.4 0.0 0.0096 15.8 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Big_1 PF02369.11 OAJ03048.1 - 0.073 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) RVT_2 PF07727.9 OAJ03050.1 - 1.9e-83 279.2 0.0 2.8e-83 278.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ03050.1 - 6.2e-22 77.9 0.5 3.3e-21 75.5 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain rve_3 PF13683.1 OAJ03050.1 - 5.2e-06 25.8 0.0 1.7e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ03050.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) FHA PF00498.21 OAJ03075.1 - 0.0014 18.6 0.0 0.084 13.0 0.0 2.4 2 0 0 2 2 2 2 FHA domain RVT_1 PF00078.22 OAJ03193.1 - 1.9e-18 66.6 0.0 4e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ03193.1 - 7e-14 51.9 0.0 1.4e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain KfrA_N PF11740.3 OAJ03193.1 - 1.1 9.7 7.9 4 7.9 0.4 2.5 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Pkinase PF00069.20 OAJ03223.1 - 1.3e-52 178.5 0.0 1.3e-52 178.5 0.0 2.7 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ03223.1 - 5.9e-20 71.4 0.0 5.9e-20 71.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 OAJ03223.1 - 0.003 17.3 0.1 0.003 17.3 0.0 4.1 3 1 1 4 4 4 1 Phosphotransferase enzyme family Med15 PF09606.5 OAJ03223.1 - 0.024 12.8 142.3 0.017 13.3 83.9 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2763 PF10961.3 OAJ03223.1 - 0.93 9.9 6.5 6 7.3 0.2 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) rve PF00665.21 OAJ03256.1 - 1e-13 51.4 0.0 3.1e-12 46.6 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 OAJ03256.1 - 0.0015 17.8 0.1 0.0037 16.6 0.1 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger PAZ PF02170.17 OAJ03256.1 - 0.078 12.2 0.0 0.24 10.6 0.0 1.7 2 0 0 2 2 2 0 PAZ domain RVT_1 PF00078.22 OAJ03256.1 - 0.23 10.8 0.0 0.5 9.6 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_S14 PF00253.16 OAJ03290.1 - 6.4e-19 67.0 0.1 1.1e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e QLQ PF08880.6 OAJ03290.1 - 0.14 11.5 1.9 0.18 11.2 0.2 2.0 2 1 0 2 2 2 0 QLQ Ribosomal_L12 PF00542.14 OAJ03291.1 - 1.5e-19 69.7 8.7 5.3e-19 67.9 3.8 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Med7 PF05983.6 OAJ03292.1 - 4.7e-33 114.2 5.1 4.9e-32 110.9 3.5 1.9 1 1 0 1 1 1 1 MED7 protein Rootletin PF15035.1 OAJ03292.1 - 0.0075 16.2 0.5 0.01 15.8 0.3 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DUF607 PF04678.8 OAJ03292.1 - 0.014 15.3 0.2 0.021 14.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF342 PF03961.8 OAJ03292.1 - 0.016 13.6 0.2 0.022 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FAM75 PF14650.1 OAJ03292.1 - 0.083 12.2 2.0 0.11 11.9 0.3 1.7 1 1 1 2 2 2 0 FAM75 family FliJ PF02050.11 OAJ03292.1 - 0.089 12.8 2.3 0.15 12.1 1.6 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein tRNA-synt_1b PF00579.20 OAJ03372.1 - 3e-59 200.5 0.0 8.9e-59 198.9 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) MSP1_C PF07462.6 OAJ03372.1 - 1.8 6.8 6.6 3.8 5.8 4.6 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Rad60-SLD PF11976.3 OAJ03373.1 - 1.2e-23 82.5 0.2 1.5e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 OAJ03373.1 - 7.6e-10 38.0 0.0 9.6e-10 37.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family RVT_2 PF07727.9 OAJ03442.1 - 2.2e-60 203.6 0.0 3.4e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ03442.1 - 9.2e-19 67.7 0.0 4.5e-18 65.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 OAJ03442.1 - 8.4e-14 51.1 0.0 1.5e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ03442.1 - 1.1e-08 34.8 0.1 2.1e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ03442.1 - 1.7e-06 27.6 1.9 1.7e-06 27.6 1.3 1.9 2 0 0 2 2 2 1 Zinc knuckle gag_pre-integrs PF13976.1 OAJ03442.1 - 2.4e-06 27.0 0.0 4.9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ03442.1 - 0.017 14.6 0.0 0.05 13.1 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain UBN2_3 PF14244.1 OAJ03442.1 - 0.099 12.1 0.1 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 OAJ03442.1 - 0.77 9.4 2.8 0.58 9.8 0.4 2.0 2 0 0 2 2 2 0 Zinc knuckle 2OG-FeII_Oxy_3 PF13640.1 OAJ03444.1 - 2.1e-05 24.9 0.1 4.3e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ03444.1 - 0.0002 21.6 0.0 0.00042 20.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FlgD_ig PF13860.1 OAJ03517.1 - 0.045 13.4 0.1 0.085 12.6 0.1 1.5 1 0 0 1 1 1 0 FlgD Ig-like domain MFS_1 PF07690.11 OAJ03558.1 - 2.9e-19 68.9 7.0 2.9e-19 68.9 4.9 1.7 1 1 0 2 2 2 1 Major Facilitator Superfamily Asp PF00026.18 OAJ03560.1 - 2.3e-114 381.9 0.2 2.8e-114 381.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ03560.1 - 5.1e-11 42.7 0.0 1.1e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 OAJ03560.1 - 1.1e-06 28.3 0.0 3.1e-05 23.5 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 OAJ03560.1 - 4e-06 27.2 0.0 0.017 15.5 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease DUF3564 PF12087.3 OAJ03560.1 - 0.047 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) DUF1768 PF08719.6 OAJ03563.1 - 2.4e-27 95.6 0.0 3.9e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PALP PF00291.20 OAJ03639.1 - 1.8e-59 201.4 0.5 6.8e-37 127.3 0.1 2.0 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme hGDE_N PF14699.1 OAJ03683.1 - 0.14 12.0 0.3 0.58 10.0 0.0 2.0 1 1 1 2 2 2 0 N-terminal domain from the human glycogen debranching enzyme DUF4064 PF13273.1 OAJ03725.1 - 0.12 12.4 5.1 4.5 7.4 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) PGG PF13962.1 OAJ03725.1 - 0.24 11.0 2.9 0.25 10.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function Arif-1 PF06770.6 OAJ03725.1 - 6.3 6.1 8.3 1.1 8.5 0.1 2.5 3 0 0 3 3 3 0 Actin-rearrangement-inducing factor (Arif-1) RNase_H PF00075.19 OAJ03759.1 - 2.3e-07 31.1 0.0 3.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 RNase H Pkinase PF00069.20 OAJ03798.1 - 2.5e-41 141.5 0.0 3.1e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ03798.1 - 2.5e-26 92.3 0.0 3e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ03798.1 - 0.032 13.9 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family ResIII PF04851.10 OAJ03800.1 - 1.9e-16 60.4 0.0 4e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ03800.1 - 1.2e-12 47.5 0.0 2.2e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ03800.1 - 4.8e-12 45.5 0.0 1.1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 OAJ03800.1 - 0.0017 17.1 0.0 0.0027 16.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 OAJ03800.1 - 0.0021 18.2 0.0 0.0053 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 OAJ03800.1 - 0.0027 16.6 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 OAJ03800.1 - 0.0028 17.6 0.2 0.01 15.8 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 OAJ03800.1 - 0.048 13.2 2.3 4.8 6.6 0.0 3.0 2 1 1 3 3 3 0 AAA domain MobB PF03205.9 OAJ03800.1 - 0.1 12.2 0.0 0.4 10.3 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RVT_2 PF07727.9 OAJ03835.1 - 2.6e-62 209.9 0.0 2.4e-54 183.9 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ03835.1 - 7.9e-21 74.3 0.0 5.9e-20 71.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ03835.1 - 4.3e-05 23.0 0.0 8.3e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_2 PF14227.1 OAJ03836.1 - 6.6e-12 45.0 0.0 9.4e-12 44.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ03836.1 - 1.4e-07 31.2 0.0 2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ03836.1 - 0.0014 18.4 3.9 0.0033 17.2 2.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ03836.1 - 0.0026 17.2 2.4 0.0055 16.1 0.8 2.1 2 0 0 2 2 2 1 Zinc knuckle Copper-fist PF00649.13 OAJ03836.1 - 0.085 12.0 0.2 0.26 10.5 0.1 1.8 1 0 0 1 1 1 0 Copper fist DNA binding domain RVP PF00077.15 OAJ03836.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease SH3_9 PF14604.1 OAJ03874.1 - 1.5e-07 30.9 0.0 2.7e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ03874.1 - 3.4e-06 26.3 0.0 7e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain TMEM51 PF15345.1 OAJ03874.1 - 0.0062 16.2 0.2 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 Transmembrane protein 51 gpUL132 PF11359.3 OAJ03874.1 - 0.047 13.0 0.1 0.047 13.0 0.1 2.3 2 0 0 2 2 2 0 Glycoprotein UL132 DDE_1 PF03184.14 OAJ03952.1 - 6.2e-20 71.2 1.8 3.6e-18 65.5 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease Ribosomal_60s PF00428.14 OAJ03952.1 - 0.0056 17.0 3.0 0.11 12.8 1.6 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein DDE_3 PF13358.1 OAJ03952.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Helicase_C_2 PF13307.1 OAJ03986.1 - 1.9e-23 83.2 0.5 5.7e-23 81.6 0.4 1.7 1 1 0 1 1 1 1 Helicase C-terminal domain FLILHELTA PF10306.4 OAJ04021.1 - 1.5e-13 50.5 0.1 3.4e-13 49.4 0.1 1.7 1 1 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 OAJ04021.1 - 0.0072 16.5 0.3 0.012 15.8 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Chorein_N PF12624.2 OAJ04023.1 - 3.6e-07 29.7 0.0 4.1e-06 26.3 0.0 2.4 1 1 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Glyco_hydro_45 PF02015.11 OAJ04052.1 - 9.3e-14 51.9 2.9 1.8e-11 44.5 0.6 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 45 PAS_9 PF13426.1 OAJ04092.1 - 2.7e-19 69.4 0.0 5.7e-18 65.2 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 OAJ04092.1 - 3.7e-07 29.9 0.0 1.1e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 OAJ04092.1 - 1.2e-05 25.2 0.0 0.00013 21.9 0.0 2.6 3 0 0 3 3 3 1 PAS fold RGS PF00615.14 OAJ04092.1 - 3.2e-05 23.9 0.0 5.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS_3 PF08447.6 OAJ04092.1 - 0.007 16.4 0.0 0.4 10.8 0.0 3.0 3 0 0 3 3 3 1 PAS fold Myb_DNA-bind_3 PF12776.2 OAJ04094.1 - 2.9e-17 63.0 1.0 4.9e-17 62.3 0.7 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ04094.1 - 1.6e-08 34.5 2.0 4e-08 33.2 1.4 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ04094.1 - 0.0096 16.0 0.5 0.022 14.8 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain PBP1_TM PF14812.1 OAJ04094.1 - 0.12 12.6 2.4 0.33 11.2 1.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_18 PF13512.1 OAJ04095.1 - 0.0038 17.2 0.0 0.0042 17.1 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat YfiO PF13525.1 OAJ04095.1 - 0.084 12.3 0.0 0.087 12.2 0.0 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein COesterase PF00135.23 OAJ04135.1 - 3.2e-102 342.9 0.0 4.4e-102 342.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ04135.1 - 1.6e-10 40.9 1.2 9e-10 38.4 0.9 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ04135.1 - 0.00071 19.3 0.3 0.0041 16.8 0.2 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ04135.1 - 0.011 15.0 0.3 0.019 14.1 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ribosomal_L10 PF00466.15 OAJ04172.1 - 1.5e-24 85.7 0.0 3.1e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 OAJ04172.1 - 2.8e-24 85.3 10.6 2.8e-24 85.3 7.4 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein ATP-synt_ab_C PF00306.22 OAJ04206.1 - 0.51 10.8 8.3 0.98 9.9 5.8 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain TFIIA PF03153.8 OAJ04206.1 - 8.8 6.1 17.6 2.1 8.1 8.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ThylakoidFormat PF11264.3 OAJ04244.1 - 0.024 14.2 0.2 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 Thylakoid formation protein DUF948 PF06103.6 OAJ04244.1 - 0.099 12.5 2.6 0.11 12.3 0.3 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Vma12 PF11712.3 OAJ04247.1 - 2.8e-27 95.1 0.0 5.2e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase TFIIIC_sub6 PF10419.4 OAJ04247.1 - 3.5e-09 35.9 0.0 6.3e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit DUF1772 PF08592.6 OAJ04247.1 - 0.0045 16.7 1.9 0.008 15.9 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) PA_decarbox PF05870.6 OAJ04247.1 - 0.091 12.2 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) Band_7 PF01145.20 OAJ04248.1 - 3.1e-24 85.8 4.4 3.8e-24 85.5 1.7 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family RskA PF10099.4 OAJ04283.1 - 0.17 11.6 3.1 0.23 11.1 2.1 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA NARP1 PF12569.3 OAJ04324.1 - 2 7.1 11.3 3.5 6.2 7.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BLVR PF06375.6 OAJ04324.1 - 3.7 7.3 19.6 0.31 10.8 6.9 3.1 3 0 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) U79_P34 PF03064.11 OAJ04324.1 - 5.3 6.4 13.3 18 4.7 9.2 1.9 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Myb_DNA-bind_3 PF12776.2 OAJ04367.1 - 0.0098 16.4 0.0 0.013 16.1 0.0 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain rve PF00665.21 OAJ04370.1 - 5.8e-14 52.2 0.0 1.4e-12 47.8 0.0 2.5 2 1 1 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ04370.1 - 1.8e-08 33.8 0.0 4.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Transcript_VP30 PF11507.3 OAJ04370.1 - 0.076 12.8 0.1 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 RVP PF00077.15 OAJ04370.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease E3_binding PF02817.12 OAJ04412.1 - 1.4e-09 37.4 0.0 3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 e3 binding domain Response_reg PF00072.19 OAJ04413.1 - 6e-08 32.6 0.0 7.4e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain DDE_3 PF13358.1 OAJ04454.1 - 2.3e-16 59.8 0.0 3.7e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAJ04454.1 - 1.4e-05 25.7 0.2 5e-05 24.0 0.1 2.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 OAJ04454.1 - 0.00014 21.9 0.1 0.00052 20.1 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 OAJ04454.1 - 0.00027 20.9 0.3 0.00072 19.5 0.2 1.8 1 0 0 1 1 1 1 Transposase DDE_1 PF03184.14 OAJ04454.1 - 0.0038 16.4 0.0 0.0069 15.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_hydro_47 PF01532.15 OAJ04495.1 - 6.1e-130 433.8 0.0 1.2e-129 432.9 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 AIG1 PF04548.11 OAJ04497.1 - 0.043 12.9 0.1 0.16 11.0 0.0 1.8 1 1 1 2 2 2 0 AIG1 family Glyco_trans_1_4 PF13692.1 OAJ04561.1 - 3.6e-18 65.9 0.1 2.8e-15 56.6 0.0 3.6 4 0 0 4 4 4 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 OAJ04561.1 - 4.8e-05 22.8 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 OAJ04561.1 - 9.5e-05 22.6 0.0 0.00028 21.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Nucleoplasmin PF03066.10 OAJ04561.1 - 0.7 9.4 3.7 1.6 8.2 2.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 OAJ04561.1 - 6.4 4.5 20.8 0.091 10.6 8.4 2.3 1 1 0 2 2 2 0 Sporozoite P67 surface antigen Ribosomal_S27 PF01599.14 OAJ04564.1 - 0.09 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S27a GSK-3_bind PF05350.7 OAJ04565.1 - 1.5 8.2 4.7 0.7 9.2 1.9 1.4 1 1 0 1 1 1 0 Glycogen synthase kinase-3 binding Glutaredoxin PF00462.19 OAJ04655.1 - 6.3e-19 67.7 0.0 1e-17 63.8 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 OAJ04655.1 - 2.8e-17 62.2 0.0 5e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 OAJ04655.1 - 1.2e-05 25.2 0.1 0.0069 16.4 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ04655.1 - 0.0021 18.2 0.0 0.011 15.8 0.0 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.6 OAJ04655.1 - 0.0066 16.3 0.0 0.033 14.0 0.0 2.1 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE GST_N_3 PF13417.1 OAJ04655.1 - 0.068 13.3 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ArsC PF03960.10 OAJ04655.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 ArsC family RVT_1 PF00078.22 OAJ04695.1 - 4.6e-18 65.3 0.0 7.4e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 OAJ04695.1 - 0.0057 16.6 0.6 0.012 15.5 0.4 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Macoilin PF09726.4 OAJ04696.1 - 0.64 8.2 11.0 0.69 8.1 7.7 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 OAJ04696.1 - 2.2 7.7 19.7 2.5 7.5 13.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Pkinase PF00069.20 OAJ04743.1 - 2.4e-41 141.5 0.0 3.5e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04743.1 - 1.7e-26 92.8 0.0 2.3e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ04743.1 - 0.0019 18.0 1.0 0.0043 16.8 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ04743.1 - 0.0033 16.4 0.0 0.034 13.1 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 OAJ04743.1 - 0.087 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Transposase_21 PF02992.9 OAJ04785.1 - 6e-18 64.7 0.1 1.1e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Mpv17_PMP22 PF04117.7 OAJ04834.1 - 8e-09 35.0 0.8 9.9e-08 31.5 0.6 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family Sigma70_r1_2 PF00140.15 OAJ04834.1 - 0.12 12.0 0.2 0.44 10.2 0.1 1.9 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 CaM_bdg_C0 PF10562.4 OAJ04834.1 - 0.16 11.8 0.5 0.28 11.0 0.4 1.4 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit RRM_1 PF00076.17 OAJ04835.1 - 1.2e-18 66.5 0.0 2.2e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ04835.1 - 8.5e-12 44.8 0.0 1.4e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ04835.1 - 1.8e-09 37.2 0.0 2.9e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAJ04835.1 - 0.0053 16.4 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Tim17 PF02466.14 OAJ04836.1 - 7.6e-37 126.2 4.3 1.1e-36 125.7 3.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 OAJ04836.1 - 0.07 13.0 0.6 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) DUF4117 PF13491.1 OAJ04836.1 - 0.12 11.8 1.5 0.94 8.9 1.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4117) bZIP_2 PF07716.10 OAJ04882.1 - 0.0022 17.7 6.1 0.0022 17.7 4.2 1.6 2 0 0 2 2 2 1 Basic region leucine zipper DUF4515 PF14988.1 OAJ04882.1 - 0.0027 17.3 1.3 0.0035 17.0 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) GLTSCR1 PF15249.1 OAJ04882.1 - 0.0058 16.7 0.2 0.008 16.2 0.2 1.3 1 0 0 1 1 1 1 Glioma tumor suppressor candidate region NYD-SP28_assoc PF14775.1 OAJ04882.1 - 0.016 14.8 3.2 0.029 14.0 2.2 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF349 PF03993.7 OAJ04882.1 - 0.036 14.2 7.2 0.052 13.6 5.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Mnd1 PF03962.10 OAJ04882.1 - 0.042 13.5 2.0 0.048 13.3 1.4 1.1 1 0 0 1 1 1 0 Mnd1 family DUF3138 PF11336.3 OAJ04882.1 - 0.54 8.3 5.6 0.57 8.2 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Pkinase PF00069.20 OAJ04929.1 - 1.2e-54 185.1 0.0 2.4e-54 184.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04929.1 - 1.1e-24 86.9 0.0 1.8e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ04929.1 - 0.0051 16.5 0.2 0.022 14.4 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ04929.1 - 0.021 13.7 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RNA_pol_Rpb6 PF01192.17 OAJ04930.1 - 3.7e-20 71.4 0.3 5.4e-20 70.9 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 RVT_1 PF00078.22 OAJ04964.1 - 1.6e-17 63.6 0.0 3.2e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ04964.1 - 8.3e-15 54.9 0.0 2e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Herpes_ORF11 PF04797.8 OAJ04964.1 - 0.34 9.3 0.0 0.53 8.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus dUTPase protein FlaC_arch PF05377.6 OAJ04966.1 - 0.0094 15.8 6.3 3.3 7.6 0.1 4.7 5 0 0 5 5 5 1 Flagella accessory protein C (FlaC) LOH1CR12 PF10158.4 OAJ04966.1 - 0.029 14.1 1.8 0.08 12.7 0.6 2.2 2 0 0 2 2 2 0 Tumour suppressor protein HTH_1 PF00126.22 OAJ04966.1 - 0.09 12.5 0.1 0.09 12.5 0.1 3.8 4 0 0 4 4 4 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF976 PF06162.7 OAJ04966.1 - 0.099 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF976) DivIVA PF05103.8 OAJ04966.1 - 0.33 11.0 43.5 1.2 9.2 3.9 5.7 4 1 1 5 5 5 0 DivIVA protein Mnd1 PF03962.10 OAJ04966.1 - 3.5 7.2 28.6 1.5 8.4 0.1 4.4 2 1 2 4 4 4 0 Mnd1 family CPSase_sm_chain PF00988.17 OAJ04967.1 - 5.1e-44 148.9 0.0 7.8e-44 148.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 OAJ04967.1 - 5.3e-36 123.8 0.0 5.8e-35 120.4 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 OAJ04967.1 - 2.9e-05 23.6 0.2 0.00022 20.7 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 PHD PF00628.24 OAJ05013.1 - 0.003 17.2 10.5 0.0087 15.7 7.3 1.8 1 0 0 1 1 1 1 PHD-finger Pex14_N PF04695.8 OAJ05013.1 - 2.2 8.3 8.8 4.3 7.3 6.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region rve PF00665.21 OAJ05014.1 - 0.00033 20.7 0.1 0.00071 19.6 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain Herpes_capsid PF06112.6 OAJ05065.1 - 0.15 12.0 5.7 0.18 11.8 4.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein EHN PF06441.7 OAJ05066.1 - 1.7e-26 92.2 0.0 3.1e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 OAJ05066.1 - 5e-07 29.8 2.1 7e-07 29.3 1.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ05066.1 - 0.00047 19.7 0.0 0.00096 18.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold TPR_12 PF13424.1 OAJ05069.1 - 5.7e-10 38.9 11.3 0.0054 16.6 0.0 6.1 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ05069.1 - 5.6e-08 32.1 2.5 0.79 9.7 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ05069.1 - 6.7e-06 25.6 1.0 0.35 10.5 0.0 4.3 4 0 0 4 4 4 2 TPR repeat TPR_7 PF13176.1 OAJ05069.1 - 4.6e-05 22.9 2.9 1.1 9.2 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ05069.1 - 0.00013 21.4 0.5 3 7.6 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ05069.1 - 0.00029 21.1 5.3 0.05 14.2 0.1 5.7 5 1 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ05069.1 - 0.0038 16.8 0.0 19 5.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ05069.1 - 0.015 15.6 0.2 1 9.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 OAJ05069.1 - 0.017 15.2 0.2 19 5.5 0.0 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 OAJ05069.1 - 0.018 14.9 9.3 15 5.7 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ05069.1 - 0.093 13.4 8.0 0.093 13.4 1.2 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ05069.1 - 0.54 10.8 0.1 0.54 10.8 0.0 3.8 3 0 0 3 3 2 0 Tetratricopeptide repeat Helicase_C PF00271.26 OAJ05158.1 - 2.8e-10 39.8 0.0 6.8e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ05159.1 - 4.4e-06 26.2 0.1 5.3e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2392 PF10288.4 OAJ05159.1 - 0.046 14.0 0.0 0.06 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) AAA_19 PF13245.1 OAJ05159.1 - 0.068 12.9 0.0 0.077 12.7 0.0 1.4 1 1 0 1 1 1 0 Part of AAA domain Mpv17_PMP22 PF04117.7 OAJ05159.1 - 0.13 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Mpv17 / PMP22 family RVT_1 PF00078.22 OAJ05251.1 - 7.2e-17 61.4 0.0 1.3e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ05251.1 - 7.7e-13 48.6 0.0 1.8e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain TruD PF01142.13 OAJ05351.1 - 5.1e-41 140.5 0.1 9.2e-30 103.5 0.0 6.3 5 2 0 5 5 5 3 tRNA pseudouridine synthase D (TruD) WD40 PF00400.27 OAJ05353.1 - 3.2e-26 90.2 16.9 5.4e-06 26.0 0.0 6.7 6 1 0 6 6 6 5 WD domain, G-beta repeat CLTH PF10607.4 OAJ05353.1 - 8.7e-06 25.4 0.1 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SGL PF08450.7 OAJ05353.1 - 0.0018 17.6 0.0 0.096 12.0 0.0 2.7 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region CDO_I PF05995.7 OAJ05409.1 - 7.3e-07 28.5 0.1 1.4e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 OAJ05409.1 - 0.0076 15.6 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) ASF1_hist_chap PF04729.8 OAJ05455.1 - 1.1e-13 51.0 0.0 1.6e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone ICL PF00463.16 OAJ05456.1 - 5.5e-100 335.0 4.8 7.8e-51 172.8 2.0 3.8 1 1 0 2 2 2 2 Isocitrate lyase family DUF3549 PF12069.3 OAJ05458.1 - 0.05 12.3 0.2 0.077 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) DUF3138 PF11336.3 OAJ05458.1 - 3.1 5.8 5.6 5.1 5.1 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Helitron_like_N PF14214.1 OAJ05550.1 - 8.1e-32 110.4 0.0 1.4e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Gelsolin PF00626.17 OAJ05553.1 - 1.7e-38 130.1 0.0 7.4e-15 54.4 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat DUF4243 PF14027.1 OAJ05554.1 - 7.9e-69 232.6 4.0 1.1e-68 232.1 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Phage_int_SAM_1 PF02899.12 OAJ05587.1 - 0.0088 16.1 0.0 0.04 14.0 0.0 2.0 1 1 1 2 2 2 1 Phage integrase, N-terminal SAM-like domain Mito_carr PF00153.22 OAJ05638.1 - 5.3e-06 26.0 2.0 0.012 15.3 0.0 2.8 2 1 0 2 2 2 2 Mitochondrial carrier protein rve PF00665.21 OAJ05641.1 - 1.5e-08 34.8 0.0 4.3e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain HTH_OrfB_IS605 PF12323.3 OAJ05698.1 - 2.1e-10 39.7 0.6 3.9e-10 38.8 0.4 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Aldo_ket_red PF00248.16 OAJ05757.1 - 2.7e-30 105.1 0.0 3.5e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3701 PF12482.3 OAJ05758.1 - 0.024 14.3 0.4 0.21 11.3 0.0 2.6 2 1 1 3 3 3 0 Phage integrase protein Dimer_Tnp_hAT PF05699.9 OAJ05761.1 - 7.4e-11 41.5 0.0 1.6e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ESR1_C PF12743.2 OAJ05761.1 - 0.11 12.0 0.2 0.36 10.4 0.2 1.8 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal PIF1 PF05970.9 OAJ05762.1 - 9.9e-36 123.4 0.0 2.9e-35 121.8 0.0 1.7 1 1 0 1 1 1 1 PIF1-like helicase RVT_1 PF00078.22 OAJ05815.1 - 8.6e-15 54.6 0.0 1.8e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 OAJ05815.1 - 0.0025 17.6 2.5 0.0047 16.7 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ05815.1 - 0.027 13.9 0.8 0.059 12.8 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.20 OAJ05866.1 - 3.3e-71 239.4 0.0 4.6e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ05866.1 - 3e-39 134.6 0.0 5e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 OAJ05866.1 - 1.2e-07 31.2 0.1 3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 OAJ05866.1 - 3.9e-05 22.8 0.1 0.00014 20.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ05866.1 - 0.0009 18.2 0.0 0.01 14.7 0.0 2.3 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 OAJ05866.1 - 0.0015 17.9 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 OAJ05866.1 - 0.0036 17.0 0.6 0.033 13.9 0.0 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 OAJ05866.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinesin-relat_1 PF12711.2 OAJ05866.1 - 0.15 12.5 0.5 1.6 9.1 0.0 2.5 3 0 0 3 3 3 0 Kinesin motor MPC PF03650.8 OAJ05931.1 - 2.2e-37 127.6 0.4 2.4e-37 127.5 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) ILVD_EDD PF00920.16 OAJ05932.1 - 8.5e-196 651.3 0.1 1e-195 651.1 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family CTK3 PF12243.3 OAJ05985.1 - 2.2e-28 98.6 0.0 4.1e-28 97.7 0.0 1.4 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 OAJ05985.1 - 4.1e-14 52.3 2.0 6.9e-11 42.0 0.1 2.5 2 0 0 2 2 2 2 CTD kinase subunit gamma CTK3 C-terminus Pho88 PF10032.4 OAJ05986.1 - 1.3e-60 203.9 0.0 1.4e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DEC-1_N PF04625.8 OAJ05986.1 - 1.4 7.5 6.4 2 6.9 4.4 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Ribosomal_60s PF00428.14 OAJ05986.1 - 2.3 8.6 9.8 3.4 8.1 6.8 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein RabGAP-TBC PF00566.13 OAJ06048.1 - 2.2e-48 164.5 0.0 2.9e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RVT_1 PF00078.22 OAJ06098.1 - 1.3e-18 67.1 0.0 2.4e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ06098.1 - 8e-15 55.0 0.0 2.5e-14 53.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ06098.1 - 0.0002 21.7 0.0 0.00049 20.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ06098.1 - 0.0025 17.6 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ06098.1 - 0.014 15.1 0.1 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease dUTPase PF00692.14 OAJ06098.1 - 0.27 10.6 0.0 0.58 9.6 0.0 1.5 1 0 0 1 1 1 0 dUTPase PH PF00169.24 OAJ06162.1 - 5.8e-07 29.6 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 PH domain Nucleoplasmin PF03066.10 OAJ06162.1 - 0.33 10.4 6.4 3.2 7.2 5.6 1.7 2 0 0 2 2 2 0 Nucleoplasmin Paf1 PF03985.8 OAJ06162.1 - 0.34 9.5 7.1 0.64 8.7 4.9 1.3 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.7 OAJ06162.1 - 1.1 7.0 9.6 2.4 5.9 6.6 1.5 1 0 0 1 1 1 0 Nop14-like family CAF1A PF12253.3 OAJ06162.1 - 1.2 9.2 8.8 3 8.0 5.4 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A RVT_1 PF00078.22 OAJ06165.1 - 2.3e-18 66.3 0.0 3.8e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ06165.1 - 1e-05 25.6 0.0 2.7e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ06279.1 - 5.8e-19 68.3 0.0 9.9e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ06279.1 - 3e-15 56.3 0.0 7.4e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ06279.1 - 0.0099 16.3 0.1 0.053 14.0 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease Dimer_Tnp_hAT PF05699.9 OAJ06331.1 - 1.7e-18 66.0 0.5 5.4e-18 64.3 0.4 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAJ06331.1 - 0.00077 19.4 0.0 0.0033 17.3 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) DEAD PF00270.24 OAJ06334.1 - 1.8e-46 157.7 0.0 3.1e-46 156.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ06334.1 - 7.4e-27 93.0 0.0 1.7e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ06334.1 - 0.019 14.7 0.0 0.054 13.3 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Transferase PF02458.10 OAJ06335.1 - 0.00016 20.2 0.0 0.46 8.8 0.0 2.8 3 0 0 3 3 3 2 Transferase family Condensation PF00668.15 OAJ06335.1 - 0.15 10.9 0.0 14 4.4 0.0 2.2 2 0 0 2 2 2 0 Condensation domain Aa_trans PF01490.13 OAJ06457.1 - 2.7e-57 194.1 7.7 1.2e-56 191.9 5.3 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 OAJ06457.1 - 0.00029 19.7 5.5 0.00029 19.7 3.8 2.0 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family YL1 PF05764.8 OAJ06457.1 - 0.08 12.5 8.2 0.16 11.5 5.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 OAJ06457.1 - 0.76 7.6 14.1 1 7.1 9.8 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 OAJ06457.1 - 0.95 7.8 13.0 1.6 7.0 9.0 1.3 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 OAJ06457.1 - 3.9 6.6 14.0 6.9 5.8 9.7 1.4 1 0 0 1 1 1 0 SDA1 rve PF00665.21 OAJ06580.1 - 2.1e-21 76.2 0.0 3.9e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ06580.1 - 0.0014 18.1 2.1 0.0019 17.7 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain Helicase_C PF00271.26 OAJ06583.1 - 3.4e-11 42.8 0.0 7.9e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ06583.1 - 0.0081 15.6 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Prominin PF05478.6 OAJ06584.1 - 0.033 11.7 0.1 0.046 11.2 0.0 1.1 1 0 0 1 1 1 0 Prominin rve PF00665.21 OAJ06644.1 - 2.5e-16 59.8 0.0 3.7e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Clr2 PF10383.4 OAJ06644.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 RVT_1 PF00078.22 OAJ06646.1 - 1.8e-14 53.6 0.0 2.8e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UCH_1 PF13423.1 OAJ06705.1 - 5.4e-36 124.5 0.0 1.1e-35 123.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 OAJ06705.1 - 3.4e-21 76.2 0.0 6e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 OAJ06705.1 - 0.00062 18.9 0.0 0.28 10.2 0.0 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_pol_A_exo1 PF01612.15 OAJ06707.1 - 1e-14 54.3 0.0 2.2e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease SR-25 PF10500.4 OAJ06707.1 - 2.2 7.6 22.7 0.016 14.6 7.5 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SRP19 PF01922.12 OAJ06708.1 - 5.8e-18 65.2 0.3 1.2e-17 64.2 0.0 1.6 2 0 0 2 2 2 1 SRP19 protein EF-hand_1 PF00036.27 OAJ06776.1 - 3.1e-20 69.8 0.1 6e-06 25.1 0.0 4.4 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 OAJ06776.1 - 8.8e-19 65.6 0.1 4.4e-07 29.2 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 OAJ06776.1 - 1.3e-16 59.0 0.1 0.00058 19.0 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 OAJ06776.1 - 8e-15 54.7 0.0 6.9e-06 26.1 0.1 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 OAJ06776.1 - 8.7e-11 41.2 1.2 4.9e-06 26.0 0.0 3.6 3 2 2 5 5 5 4 EF-hand domain pair Nop PF01798.13 OAJ06847.1 - 1e-54 183.9 1.0 2.4e-54 182.7 0.7 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 OAJ06847.1 - 5.7e-26 90.0 0.1 1e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 OAJ06847.1 - 6.1e-11 42.3 0.0 1.9e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Nop16 PF09420.5 OAJ06848.1 - 7.6e-35 120.4 0.0 9.3e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 PAT1 PF09770.4 OAJ06849.1 - 9.3 4.3 48.2 11 4.0 33.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Histone PF00125.19 OAJ06852.1 - 5.7e-09 35.9 0.0 1.4e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Dimer_Tnp_hAT PF05699.9 OAJ06853.1 - 1.5e-14 53.3 0.0 3.3e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAJ06853.1 - 0.088 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) ORC6 PF05460.8 OAJ06854.1 - 3.7 6.5 8.2 4 6.4 5.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TP53IP5 PF15331.1 OAJ06854.1 - 4.8 7.0 6.3 5.5 6.8 4.3 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 LIP PF03583.9 OAJ06923.1 - 1.5e-27 96.6 4.1 2.1e-27 96.0 2.9 1.2 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 OAJ06923.1 - 0.0095 15.6 0.4 0.016 14.9 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family GFA PF04828.9 OAJ06926.1 - 5.3e-08 32.6 0.3 1.3e-05 25.0 0.1 2.3 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF3580 PF12117.3 OAJ06926.1 - 0.064 13.1 1.2 0.68 9.8 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3580) Inhibitor_Mig-6 PF11555.3 OAJ07069.1 - 0.026 14.8 3.0 0.05 13.9 2.1 1.4 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 rve PF00665.21 OAJ07070.1 - 2.4e-10 40.5 0.0 5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ07070.1 - 0.088 12.1 0.1 0.22 10.8 0.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Rhomboid PF01694.17 OAJ07222.1 - 3.3e-30 105.0 12.3 3.3e-30 105.0 8.5 2.3 3 0 0 3 3 3 1 Rhomboid family Topoisom_bac PF01131.15 OAJ07297.1 - 2.5e-80 270.2 0.0 3.4e-80 269.8 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 OAJ07297.1 - 1.6e-20 72.9 0.0 2.9e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain zf-CCHC PF00098.18 OAJ07297.1 - 7.8e-06 25.5 4.0 1.8e-05 24.4 2.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ07297.1 - 0.23 11.2 2.7 0.33 10.7 1.2 1.8 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 OAJ07300.1 - 2.7e-16 59.6 0.0 5.4e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ07300.1 - 3.4e-14 52.9 0.0 9.6e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ07300.1 - 0.0003 21.2 0.0 0.0009 19.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ07300.1 - 0.0042 16.9 0.0 0.0092 15.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF788 PF05620.6 OAJ07384.1 - 4.4e-36 124.2 0.4 5.7e-36 123.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Ribosomal_60s PF00428.14 OAJ07384.1 - 0.35 11.2 5.7 0.083 13.2 1.2 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_S28e PF01200.13 OAJ07385.1 - 9.7e-32 108.5 1.0 1e-31 108.4 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e UEV PF05743.8 OAJ07386.1 - 5.5e-39 132.5 0.1 8.5e-39 131.9 0.1 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 OAJ07386.1 - 1.7e-23 82.0 0.3 3.2e-23 81.0 0.2 1.5 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 OAJ07386.1 - 2.8e-05 23.5 0.0 8e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IncA PF04156.9 OAJ07386.1 - 0.0096 15.5 0.0 0.0096 15.5 0.0 2.2 2 0 0 2 2 2 1 IncA protein HEAT PF02985.17 OAJ07389.1 - 4.7e-06 26.2 1.4 0.88 9.8 0.0 5.1 6 0 0 6 6 6 2 HEAT repeat Pkinase PF00069.20 OAJ07389.1 - 0.046 12.8 0.0 0.13 11.3 0.0 1.6 1 1 0 1 1 1 0 Protein kinase domain HEAT_EZ PF13513.1 OAJ07389.1 - 0.066 13.7 0.1 0.066 13.7 0.1 3.8 5 0 0 5 5 5 0 HEAT-like repeat TFIIF_alpha PF05793.7 OAJ07477.1 - 3 6.1 38.5 9.2 4.5 26.7 1.8 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.5 OAJ07477.1 - 9.6 5.1 34.4 30 3.5 23.8 1.8 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 OAJ07482.1 - 0.14 10.0 10.1 0.25 9.2 7.0 1.4 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.22 OAJ07565.1 - 4.1e-08 32.8 0.0 4.7e-08 32.6 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3762 PF12591.3 OAJ07565.1 - 0.048 13.6 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) rve PF00665.21 OAJ07566.1 - 4.7e-19 68.6 0.0 9.2e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ07566.1 - 0.0014 18.1 0.0 0.0034 16.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain AIPR PF10592.4 OAJ07566.1 - 0.1 11.8 0.1 4.7 6.4 0.1 2.1 2 0 0 2 2 2 0 AIPR protein Phage_integrase PF00589.17 OAJ07569.1 - 0.016 14.9 0.2 0.037 13.7 0.0 1.7 2 0 0 2 2 2 0 Phage integrase family TFIIF_alpha PF05793.7 OAJ07570.1 - 0.21 9.9 12.2 0.23 9.7 8.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ORC6 PF05460.8 OAJ07570.1 - 1.4 7.9 10.7 1.5 7.8 7.4 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Hepatitis_core PF00906.15 OAJ07570.1 - 2.3 7.8 7.6 2.7 7.6 4.8 1.3 1 1 0 1 1 1 0 Hepatitis core antigen SR-25 PF10500.4 OAJ07570.1 - 2.7 7.3 23.9 3.2 7.1 16.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 OAJ07570.1 - 3.4 7.7 24.8 4.5 7.3 17.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Herpes_DNAp_acc PF04929.7 OAJ07570.1 - 3.6 6.4 8.0 3.7 6.4 5.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RNA_pol_Rpc4 PF05132.9 OAJ07570.1 - 4.8 7.1 7.4 6.8 6.6 5.1 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 RVT_1 PF00078.22 OAJ07635.1 - 3.9e-15 55.7 0.0 6.1e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ07635.1 - 0.00018 21.9 0.0 0.00044 20.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ07635.1 - 0.00096 19.0 0.0 0.0025 17.7 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ07635.1 - 0.014 15.2 0.1 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RHD3 PF05879.7 OAJ07639.1 - 0.0035 15.3 0.0 0.0035 15.3 0.0 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Thi4 PF01946.12 OAJ07640.1 - 7.8e-86 286.8 0.0 1e-85 286.5 0.0 1.1 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 OAJ07640.1 - 2e-07 30.2 1.0 2e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.19 OAJ07640.1 - 3.2e-07 29.5 0.2 3.3e-06 26.2 0.1 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ07640.1 - 5.4e-06 26.3 0.1 1.8e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAJ07640.1 - 0.00036 20.4 0.0 0.00061 19.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ07640.1 - 0.0016 18.2 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 OAJ07640.1 - 0.0016 17.3 1.6 0.035 12.9 0.2 2.5 2 1 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 OAJ07640.1 - 0.07 11.5 0.1 0.1 11.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 OAJ07640.1 - 0.085 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Cpn60_TCP1 PF00118.19 OAJ07719.1 - 5.8e-139 463.8 11.3 8.7e-89 298.3 3.1 1.9 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Stomoxyn PF11585.3 OAJ07719.1 - 7.7 6.4 9.1 32 4.4 0.0 4.2 4 0 0 4 4 4 0 Insect antimicrobial peptide, stomoxyn RGS PF00615.14 OAJ07720.1 - 2.2e-12 47.0 0.0 2.3e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain SSP160 PF06933.6 OAJ07813.1 - 0.3 9.0 12.9 0.45 8.4 9.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tir_receptor_C PF07489.6 OAJ07813.1 - 0.85 9.3 9.5 1.6 8.4 6.6 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus LIP PF03583.9 OAJ07817.1 - 1.2e-52 178.8 0.1 1.7e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 OAJ07817.1 - 3.9e-07 29.9 0.1 9.1e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ07817.1 - 1.5e-06 28.2 0.0 2.8e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ07817.1 - 0.00028 20.1 0.6 0.011 14.9 0.0 2.5 2 1 0 2 2 2 1 Prolyl oligopeptidase family Cutinase PF01083.17 OAJ07817.1 - 0.093 12.4 0.3 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_2 PF02230.11 OAJ07817.1 - 0.2 11.0 0.2 1.1 8.6 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LIP PF03583.9 OAJ07818.1 - 2.1e-08 33.7 0.0 2.4e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.16 OAJ07818.1 - 0.026 13.7 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family NAD_binding_4 PF07993.7 OAJ08016.1 - 7.1e-27 93.9 0.0 1.4e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 OAJ08016.1 - 6.5e-14 51.9 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.23 OAJ08016.1 - 2.6e-09 36.0 0.0 1.2e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme 3Beta_HSD PF01073.14 OAJ08016.1 - 3.4e-06 25.9 0.0 1.5e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 OAJ08016.1 - 1.4e-05 25.0 1.0 0.00088 19.2 0.4 3.4 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 OAJ08016.1 - 4e-05 22.6 0.2 0.0071 15.2 0.0 2.8 3 0 0 3 3 3 1 RmlD substrate binding domain KR PF08659.5 OAJ08016.1 - 0.0002 21.0 1.0 0.0013 18.4 0.1 2.8 2 1 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 OAJ08016.1 - 0.0034 16.3 0.0 0.31 9.9 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein HAD_2 PF13419.1 OAJ08016.1 - 0.032 14.4 0.0 6.2 6.9 0.0 2.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AMP-binding_C PF13193.1 OAJ08016.1 - 0.073 14.0 0.5 0.29 12.1 0.1 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Kelch_4 PF13418.1 OAJ08018.1 - 9.6e-22 76.5 2.9 2.2e-07 30.5 0.0 7.2 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.1 OAJ08018.1 - 2.4e-15 56.2 13.0 0.0021 18.1 0.1 7.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 OAJ08018.1 - 1.5e-13 50.2 2.2 0.0024 17.9 0.0 6.1 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.1 OAJ08018.1 - 7.7e-12 44.8 4.4 0.0023 17.8 0.0 5.9 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 OAJ08018.1 - 9.6e-06 25.0 0.0 0.082 12.4 0.0 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 OAJ08018.1 - 0.00037 20.1 0.0 5.8 6.8 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Cupin_8 PF13621.1 OAJ08023.1 - 2.3e-46 158.3 0.3 4.2e-26 91.9 0.0 4.3 3 1 0 4 4 4 2 Cupin-like domain Clathrin_H_link PF13838.1 OAJ08024.1 - 1.5e-27 95.2 0.0 2.7e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Clathrin-H-link Luciferase_N PF05295.6 OAJ08024.1 - 0.54 10.0 2.7 3.9 7.3 0.1 2.8 3 0 0 3 3 3 0 Luciferase/LBP N-terminal domain CbiC PF02570.10 OAJ08027.1 - 0.069 12.5 0.2 0.12 11.8 0.1 1.3 1 1 0 1 1 1 0 Precorrin-8X methylmutase DUF1542 PF07564.6 OAJ08027.1 - 0.094 12.7 1.7 0.2 11.7 1.1 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1542) SSP160 PF06933.6 OAJ08031.1 - 0.02 12.8 9.3 0.027 12.4 6.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Aldo_ket_red PF00248.16 OAJ08032.1 - 2.9e-49 167.3 0.0 3.8e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Slx4 PF09494.5 OAJ08032.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Slx4 endonuclease RVT_1 PF00078.22 OAJ08037.1 - 6.3e-17 61.6 0.0 1.2e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08037.1 - 1.8e-12 47.4 0.0 6.2e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ08037.1 - 0.00075 19.9 0.1 0.0028 18.1 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAJ08037.1 - 0.0091 15.8 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ08037.1 - 0.029 14.2 0.1 0.096 12.5 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 OAJ08041.1 - 3.3e-17 62.5 0.0 6e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08041.1 - 2.1e-15 56.9 0.0 3.6e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ08041.1 - 0.00068 20.0 0.2 0.0018 18.7 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease SWIM PF04434.12 OAJ08046.1 - 5.4e-08 32.1 0.1 1e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger MULE PF10551.4 OAJ08046.1 - 1.6e-07 31.3 0.0 3.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Med11 PF10280.4 OAJ08050.1 - 0.14 12.1 1.4 0.19 11.7 1.0 1.1 1 0 0 1 1 1 0 Mediator complex protein AAA_18 PF13238.1 OAJ08051.1 - 6.4e-07 29.7 2.0 2e-06 28.1 0.1 2.5 2 1 0 2 2 2 1 AAA domain PRK PF00485.13 OAJ08051.1 - 1.4e-06 28.0 0.0 2.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 OAJ08051.1 - 0.00052 20.8 0.2 0.0029 18.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 OAJ08051.1 - 0.022 14.4 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 OAJ08051.1 - 0.058 13.2 0.3 0.15 11.9 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 OAJ08051.1 - 0.08 12.9 2.1 0.25 11.2 0.7 2.3 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 OAJ08051.1 - 0.11 11.6 0.1 0.19 10.7 0.1 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 OAJ08051.1 - 0.11 12.4 0.5 0.28 11.1 0.4 1.6 1 0 0 1 1 1 0 AAA domain GMC_oxred_N PF00732.14 OAJ08053.1 - 4.2e-48 164.0 0.2 9.7e-25 87.3 0.1 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ08053.1 - 1.2e-07 32.1 0.0 2.8e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 OAJ08053.1 - 4.8e-06 26.5 0.1 1.9e-05 24.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAJ08053.1 - 1.3e-05 24.2 0.4 0.00057 18.8 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 OAJ08053.1 - 0.00013 21.0 0.0 0.00018 20.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 OAJ08053.1 - 0.00032 19.7 0.2 0.00068 18.6 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAJ08053.1 - 0.0057 16.5 0.1 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ08053.1 - 0.014 14.4 0.1 0.03 13.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 OAJ08053.1 - 0.018 13.5 0.1 0.057 11.8 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 OAJ08053.1 - 0.032 14.2 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ08053.1 - 0.035 13.8 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 OAJ08053.1 - 0.043 12.8 0.0 0.076 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 OAJ08053.1 - 0.047 13.6 0.1 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Aldo_ket_red PF00248.16 OAJ08054.1 - 1.1e-43 149.1 0.0 1.3e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Amidohydro_1 PF01979.15 OAJ08054.1 - 0.058 13.0 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family FAD_binding_4 PF01565.18 OAJ08056.1 - 4.8e-26 90.9 4.6 6.7e-26 90.4 1.8 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 OAJ08056.1 - 2.1e-06 27.5 0.2 3.9e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like LIP PF03583.9 OAJ08062.1 - 4e-25 88.6 0.0 4.7e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 OAJ08062.1 - 0.018 14.7 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ08062.1 - 0.032 14.1 0.0 0.042 13.7 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Med3 PF11593.3 OAJ08063.1 - 0.97 8.6 8.4 1 8.5 5.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SelP_N PF04592.9 OAJ08063.1 - 3.8 6.8 7.0 5.1 6.4 4.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF566 PF04484.7 OAJ08063.1 - 8.2 5.8 10.4 11 5.4 7.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) TFIIA PF03153.8 OAJ08063.1 - 8.9 6.0 6.8 11 5.7 4.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1566 PF07603.6 OAJ08067.1 - 0.058 13.1 0.8 0.18 11.5 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1566) MULE PF10551.4 OAJ08067.1 - 0.06 13.5 0.1 0.86 9.8 0.0 2.3 1 1 1 2 2 2 0 MULE transposase domain Pneumo_matrix PF03393.11 OAJ08079.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Pneumovirus matrix protein Daxx PF03344.10 OAJ08079.1 - 0.21 10.0 16.2 0.34 9.3 11.3 1.3 1 0 0 1 1 1 0 Daxx Family TEX15 PF15326.1 OAJ08079.1 - 1.9 8.0 6.0 0.18 11.4 1.1 1.5 2 0 0 2 2 2 0 Testis expressed sequence 15 DDE_Tnp_4 PF13359.1 OAJ08080.1 - 1.1e-30 106.3 0.0 1.2e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ08080.1 - 7.2e-08 32.0 0.0 1.3e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 OAJ08080.1 - 1.6e-06 27.8 0.1 1.6e-05 24.5 0.1 2.0 1 1 0 1 1 1 1 Transposase DDE domain Pmp3 PF01679.12 OAJ08086.1 - 2.6e-12 46.2 3.2 3.7e-12 45.7 2.2 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator GST_C_2 PF13410.1 OAJ08087.1 - 1.1e-16 60.4 0.0 2e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAJ08087.1 - 7.4e-16 57.9 0.0 1.5e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ08087.1 - 3.5e-07 30.1 0.0 6.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ08087.1 - 1.3e-06 28.7 0.0 2.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAJ08087.1 - 0.0019 18.3 0.0 2 8.7 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain BBP1_C PF15272.1 OAJ08092.1 - 0.011 15.2 0.2 0.013 15.0 0.1 1.1 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Mto2_bdg PF12808.2 OAJ08092.1 - 0.015 15.3 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF1944 PF09175.5 OAJ08092.1 - 0.04 13.5 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1944) Sec2p PF06428.6 OAJ08092.1 - 0.063 13.1 0.4 0.078 12.8 0.3 1.1 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p RVT_1 PF00078.22 OAJ08094.1 - 2.6e-17 62.9 0.0 5.3e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08094.1 - 3.5e-12 46.5 0.0 8.8e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ08094.1 - 0.00013 22.3 0.0 0.00042 20.7 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ08094.1 - 0.0094 15.7 0.0 0.057 13.2 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ08094.1 - 0.035 14.0 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease TPR_12 PF13424.1 OAJ08099.1 - 4.5e-37 125.8 59.9 7.6e-08 32.1 0.2 10.2 3 3 7 12 12 12 12 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ08099.1 - 2.3e-24 84.5 56.7 0.02 14.8 0.4 15.6 16 0 0 16 16 16 11 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ08099.1 - 2.4e-10 39.5 28.8 2.2 8.3 0.1 13.0 15 0 0 15 15 14 4 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ08099.1 - 9.8e-06 24.9 9.5 12 5.7 0.0 9.3 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ08099.1 - 0.00045 19.8 36.3 1 9.0 0.6 9.6 5 2 6 11 11 11 5 TPR repeat DUF4206 PF13901.1 OAJ08099.1 - 0.0045 16.5 1.2 18 4.8 0.0 4.7 4 1 0 4 4 4 0 Domain of unknown function (DUF4206) DUF2186 PF09952.4 OAJ08099.1 - 0.0092 16.2 0.2 10 6.3 0.0 3.3 2 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2186) Ssu72 PF04722.8 OAJ08099.1 - 0.011 15.0 0.2 23 4.2 0.0 5.1 3 2 3 6 6 6 0 Ssu72-like protein M PF02370.11 OAJ08099.1 - 0.045 14.0 0.8 0.87 10.1 0.9 3.1 2 0 0 2 2 1 0 M protein repeat T2SF PF00482.18 OAJ08099.1 - 0.13 12.1 14.4 0.64 9.9 0.2 5.5 5 2 0 6 6 6 0 Type II secretion system (T2SS), protein F TPR_16 PF13432.1 OAJ08099.1 - 0.57 10.9 38.3 0.03 15.0 1.5 9.0 7 3 2 10 10 10 0 Tetratricopeptide repeat Prefoldin_2 PF01920.15 OAJ08099.1 - 0.89 9.3 8.9 26 4.6 0.1 5.5 6 0 0 6 6 6 0 Prefoldin subunit RVT_3 PF13456.1 OAJ08102.1 - 0.001 18.8 0.1 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like DNA_pol_viral_C PF00336.13 OAJ08102.1 - 0.012 14.8 0.1 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Phage_integrase PF00589.17 OAJ08103.1 - 0.00025 20.7 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DOT1 PF08123.8 OAJ08104.1 - 5.1e-65 218.6 0.0 6.9e-65 218.1 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Romo1 PF10247.4 OAJ08105.1 - 1.6e-10 40.9 1.7 2e-10 40.7 1.2 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Acetyltransf_1 PF00583.19 OAJ08107.1 - 0.00064 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ08107.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DEAD PF00270.24 OAJ08110.1 - 8.5e-46 155.5 0.0 2.2e-45 154.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ08110.1 - 1.9e-22 78.8 0.0 4.4e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 OAJ08110.1 - 4.4e-22 77.3 0.2 9e-22 76.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 OAJ08110.1 - 0.001 18.9 0.0 0.0037 17.1 0.0 2.0 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 OAJ08110.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain DDE_3 PF13358.1 OAJ08118.1 - 1.5e-18 66.9 0.0 1.7e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 OAJ08118.1 - 7.1e-05 22.9 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain 2OG-Fe_Oxy_2 PF10014.4 OAJ08118.1 - 0.03 13.7 0.3 1.7 8.0 0.0 2.0 1 1 1 2 2 2 0 2OG-Fe dioxygenase DDE_Tnp_ISAZ013 PF07592.6 OAJ08118.1 - 0.032 12.9 0.0 0.033 12.9 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain GMC_oxred_N PF00732.14 OAJ08126.1 - 1.1e-49 169.2 0.0 1.4e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ08126.1 - 3.1e-35 121.5 0.1 5.2e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAJ08126.1 - 4.1e-06 25.9 0.4 0.00028 19.9 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ08126.1 - 0.00013 21.0 1.0 0.0047 15.8 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 OAJ08126.1 - 0.00022 21.1 0.7 0.00059 19.8 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAJ08126.1 - 0.0026 16.7 0.2 0.004 16.1 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAJ08126.1 - 0.014 15.4 0.9 1.7 8.6 0.3 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ08126.1 - 0.015 15.2 0.2 0.084 12.7 0.1 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAJ08126.1 - 0.053 12.5 0.1 0.091 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DUF3336 PF11815.3 OAJ08132.1 - 1.1e-43 148.2 1.8 1.8e-43 147.4 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 OAJ08132.1 - 2.5e-21 76.5 3.3 1.3e-20 74.2 0.1 3.2 2 2 0 2 2 2 1 Patatin-like phospholipase TadE PF07811.7 OAJ08132.1 - 0.27 11.1 2.5 0.68 9.8 1.7 1.6 1 0 0 1 1 1 0 TadE-like protein RGS PF00615.14 OAJ08137.1 - 1.6e-05 24.9 0.2 5.2e-05 23.3 0.1 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain MutS_V PF00488.16 OAJ08142.1 - 4.5e-45 153.8 0.0 9.4e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAJ08142.1 - 9.9e-27 94.0 0.5 1.9e-26 93.1 0.4 1.5 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 OAJ08142.1 - 4.1e-06 26.9 1.7 0.054 13.5 0.9 3.5 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 OAJ08142.1 - 2.6e-05 24.3 0.0 6.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV SMC_N PF02463.14 OAJ08142.1 - 0.0069 15.6 0.0 1.3 8.2 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 OAJ08142.1 - 0.056 13.5 0.0 0.21 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Orthopox_F6 PF06601.7 OAJ08142.1 - 0.11 12.3 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 Orthopoxvirus F6 protein DAP3 PF10236.4 OAJ08142.1 - 0.18 10.6 3.5 0.37 9.6 0.1 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 tRNA-synt_1b PF00579.20 OAJ08146.1 - 2.4e-20 72.8 0.0 9.9e-20 70.8 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) NgoMIV_restric PF09015.5 OAJ08149.1 - 0.031 13.2 0.0 0.033 13.1 0.0 1.0 1 0 0 1 1 1 0 NgoMIV restriction enzyme Abhydrolase_3 PF07859.8 OAJ08152.1 - 1.7e-19 70.2 0.0 3.2e-19 69.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAJ08152.1 - 1.1e-07 30.7 0.0 0.0038 15.9 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 OAJ08152.1 - 0.00014 21.8 1.3 0.0002 21.2 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ08152.1 - 0.00064 19.5 0.0 0.0011 18.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Gly_rich PF12810.2 OAJ08162.1 - 0.36 10.3 49.1 0.077 12.5 28.6 3.1 1 1 1 2 2 2 0 Glycine rich protein RVT_2 PF07727.9 OAJ08166.1 - 1.7e-76 256.4 0.0 2.5e-76 255.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08166.1 - 6e-17 61.8 0.3 2.8e-16 59.6 0.1 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ08166.1 - 0.00039 20.0 0.0 0.0008 19.0 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain GCR1_C PF12550.3 OAJ08178.1 - 2.2e-19 69.1 0.1 5.8e-19 67.7 0.1 1.8 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Phage_int_SAM_1 PF02899.12 OAJ08178.1 - 0.84 9.8 5.3 1.1 9.4 0.4 3.5 3 1 1 4 4 4 0 Phage integrase, N-terminal SAM-like domain IGF2_C PF08365.6 OAJ08179.1 - 0.027 14.2 0.2 5.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide Glycolipid_bind PF06475.6 OAJ08185.1 - 0.12 11.5 0.0 0.34 10.0 0.0 1.8 2 0 0 2 2 2 0 Putative glycolipid-binding Sec7 PF01369.15 OAJ08186.1 - 5.4e-35 120.7 0.0 8.8e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 OAJ08186.1 - 4.2e-09 36.5 0.0 6.6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 OAJ08186.1 - 0.0011 19.0 0.5 0.005 16.9 0.2 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Vac_Fusion PF02346.11 OAJ08190.1 - 0.077 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus fusion protein FliD_N PF02465.13 OAJ08190.1 - 0.14 12.5 2.4 0.35 11.2 0.1 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus CAP PF00188.21 OAJ08193.1 - 6.1e-25 88.1 1.7 1e-24 87.3 1.2 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Na_Ca_ex PF01699.19 OAJ08197.1 - 1.8e-35 121.5 22.7 2e-18 66.3 6.8 3.1 2 1 0 2 2 2 2 Sodium/calcium exchanger protein BTB_2 PF02214.17 OAJ08197.1 - 0.1 12.8 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain DDE_1 PF03184.14 OAJ08205.1 - 1.5e-28 99.4 0.0 1.2e-27 96.4 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 OAJ08205.1 - 2.7e-05 23.9 0.0 0.00075 19.2 0.0 2.7 1 1 1 2 2 2 1 DDE superfamily endonuclease DDHD PF02862.12 OAJ08206.1 - 0.91 9.2 9.4 1.1 8.9 6.5 1.1 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 OAJ08206.1 - 2.1 8.2 9.7 2.4 8.0 6.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Asp-B-Hydro_N PF05279.6 OAJ08206.1 - 2.7 7.7 16.8 3.1 7.5 11.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CAF-1_p150 PF11600.3 OAJ08206.1 - 3 7.1 36.4 3.7 6.8 25.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ycf1 PF05758.7 OAJ08206.1 - 4.1 4.9 12.9 4.8 4.7 9.0 1.0 1 0 0 1 1 1 0 Ycf1 DUF1777 PF08648.7 OAJ08206.1 - 5.5 6.6 24.4 6.9 6.3 16.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF1510 PF07423.6 OAJ08206.1 - 9.4 5.5 14.1 13 5.0 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Frataxin_Cyay PF01491.11 OAJ08219.1 - 8.7e-27 93.0 0.0 1.2e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain SLD3 PF08639.5 OAJ08219.1 - 0.12 11.0 4.5 0.15 10.6 3.1 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 Apc15p PF05841.6 OAJ08219.1 - 3.1 8.5 6.3 4.6 7.9 4.4 1.3 1 0 0 1 1 1 0 Apc15p protein Ric8 PF10165.4 OAJ08220.1 - 3.7e-54 184.2 6.4 1.6e-38 132.6 0.0 3.4 3 0 0 3 3 3 3 Guanine nucleotide exchange factor synembryn RVT_2 PF07727.9 OAJ08224.1 - 2e-56 190.6 0.0 2.6e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 OAJ08225.1 - 0.0066 16.0 0.1 0.016 14.8 0.0 1.6 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-CCHC PF00098.18 OAJ08225.1 - 0.026 14.4 3.2 0.026 14.4 2.2 1.8 2 0 0 2 2 2 0 Zinc knuckle RVP PF00077.15 OAJ08225.1 - 0.076 12.9 0.0 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease UBN2_3 PF14244.1 OAJ08226.1 - 6.1e-05 22.6 0.0 6.3e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Phospholip_A2_2 PF05826.7 OAJ08226.1 - 0.093 12.6 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 Phospholipase A2 MULE PF10551.4 OAJ08229.1 - 2.8e-17 62.6 0.1 7.3e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ08229.1 - 9.7e-06 24.3 0.2 0.00038 19.1 0.0 2.1 2 0 0 2 2 2 2 Transposase, Mutator family Glyco_hydro_cc PF11790.3 OAJ08230.1 - 6.1e-44 150.2 3.5 6.9e-44 150.0 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core CDC45 PF02724.9 OAJ08237.1 - 1.6e-182 607.8 0.0 1.7e-135 452.5 0.0 2.1 1 1 1 2 2 2 2 CDC45-like protein Cas_Csy4 PF09618.5 OAJ08237.1 - 0.11 12.3 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) RVT_1 PF00078.22 OAJ08243.1 - 2.6e-20 72.6 0.0 4.5e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAJ08243.1 - 1.3e-14 54.6 0.0 3e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 OAJ08243.1 - 8.2e-13 48.0 0.1 8.2e-13 48.0 0.1 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase DivIVA PF05103.8 OAJ08246.1 - 0.0053 16.8 8.7 0.0096 15.9 6.0 1.4 1 0 0 1 1 1 1 DivIVA protein Transposase_22 PF02994.9 OAJ08246.1 - 0.012 14.1 2.4 0.015 13.7 1.6 1.2 1 0 0 1 1 1 0 L1 transposable element DUF3584 PF12128.3 OAJ08246.1 - 0.051 10.9 6.0 0.068 10.4 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RTBV_P46 PF06216.6 OAJ08246.1 - 0.07 11.9 0.1 0.097 11.4 0.0 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein APG6 PF04111.7 OAJ08246.1 - 0.2 10.6 4.5 0.27 10.2 3.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 OAJ08246.1 - 0.67 9.9 12.7 0.65 10.0 6.7 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Viral_P18 PF04521.8 OAJ08246.1 - 0.81 9.1 5.2 1.3 8.5 3.1 1.7 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DivIC PF04977.10 OAJ08246.1 - 1.4 8.4 12.1 0.92 9.0 1.7 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF4407 PF14362.1 OAJ08246.1 - 6.4 5.6 10.6 13 4.6 7.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3373 PF11853.3 OAJ08246.1 - 7.1 5.0 6.3 23 3.3 4.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) Retrotrans_gag PF03732.12 OAJ08250.1 - 0.72 9.9 3.7 0.51 10.4 0.2 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein GRP PF07172.6 OAJ08250.1 - 1.4 9.4 29.2 2.3 8.7 20.3 1.3 1 0 0 1 1 1 0 Glycine rich protein family DUF566 PF04484.7 OAJ08252.1 - 1.9 7.9 13.3 2 7.8 9.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) THOC7 PF05615.8 OAJ08255.1 - 7.5e-09 35.9 4.8 7.5e-09 35.9 3.4 2.4 1 1 1 2 2 2 1 Tho complex subunit 7 AAA_13 PF13166.1 OAJ08255.1 - 3.7e-05 22.4 2.8 5.8e-05 21.7 1.9 1.2 1 0 0 1 1 1 1 AAA domain Mnd1 PF03962.10 OAJ08255.1 - 0.00084 19.0 2.2 0.00084 19.0 1.6 2.3 1 1 1 2 2 2 1 Mnd1 family Phlebovirus_NSM PF07246.6 OAJ08255.1 - 0.031 13.4 1.7 0.034 13.3 0.2 1.7 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M ADIP PF11559.3 OAJ08255.1 - 4.1 7.2 11.3 6.7 6.6 2.3 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding GCR1_C PF12550.3 OAJ08264.1 - 2.2e-21 75.4 0.8 4.3e-21 74.5 0.5 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Steroid_dh PF02544.11 OAJ08270.1 - 1.4e-32 112.5 0.5 2.4e-32 111.8 0.3 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 OAJ08270.1 - 2.1e-07 30.5 0.1 3.5e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ubiquitin PF00240.18 OAJ08270.1 - 1.1e-05 24.7 0.0 1.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family ICMT PF04140.9 OAJ08270.1 - 0.0011 19.1 0.2 0.0025 17.9 0.1 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family COX6A PF02046.10 OAJ08270.1 - 0.0013 18.5 0.1 0.0024 17.7 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa PEMT PF04191.8 OAJ08270.1 - 0.0027 17.7 2.4 0.0097 16.0 0.5 2.3 1 1 2 3 3 3 1 Phospholipid methyltransferase DUF2986 PF11661.3 OAJ08271.1 - 0.0039 17.4 0.7 0.0039 17.4 0.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) DUF2868 PF11067.3 OAJ08271.1 - 0.31 10.1 4.5 0.57 9.2 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) WLM PF08325.5 OAJ08271.1 - 0.67 9.7 3.9 6.3 6.6 0.0 2.3 2 0 0 2 2 2 0 WLM domain AAA PF00004.24 OAJ08276.1 - 3.9e-44 150.0 0.0 6.8e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 OAJ08276.1 - 2.3e-08 34.1 0.0 4.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 OAJ08276.1 - 1.1e-06 28.3 0.0 5.8e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 OAJ08276.1 - 2e-06 28.0 0.2 0.00031 20.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ08276.1 - 2.1e-06 27.8 0.1 1.5e-05 25.0 0.0 2.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 OAJ08276.1 - 6.4e-05 22.6 0.0 0.00018 21.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 OAJ08276.1 - 7.2e-05 23.5 0.0 0.00018 22.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAJ08276.1 - 8.3e-05 21.7 0.0 0.00017 20.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 OAJ08276.1 - 0.00042 19.7 0.0 0.00088 18.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 OAJ08276.1 - 0.00098 17.9 0.0 0.002 16.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 OAJ08276.1 - 0.0013 18.5 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ08276.1 - 0.0015 18.4 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAJ08276.1 - 0.0025 16.9 0.0 0.0048 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.1 OAJ08276.1 - 0.0029 17.2 0.0 0.046 13.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 OAJ08276.1 - 0.0037 17.2 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 OAJ08276.1 - 0.0039 16.8 0.0 0.0082 15.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 OAJ08276.1 - 0.0041 16.3 0.0 0.068 12.3 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 OAJ08276.1 - 0.0069 15.5 0.1 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 OAJ08276.1 - 0.0075 16.5 0.0 0.028 14.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain DUF2072 PF09845.4 OAJ08276.1 - 0.014 15.3 0.1 0.027 14.3 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) KaiC PF06745.8 OAJ08276.1 - 0.015 14.3 0.0 0.035 13.2 0.0 1.6 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 OAJ08276.1 - 0.018 14.5 0.0 0.096 12.1 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_25 PF13481.1 OAJ08276.1 - 0.021 14.2 0.1 0.09 12.1 0.0 1.9 1 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 OAJ08276.1 - 0.027 13.4 0.0 0.052 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 OAJ08276.1 - 0.036 14.2 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 OAJ08276.1 - 0.042 13.4 0.0 0.59 9.7 0.0 2.2 1 1 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 OAJ08276.1 - 0.054 13.5 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 OAJ08276.1 - 0.056 12.3 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 OAJ08276.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Amidase PF01425.16 OAJ08277.1 - 2.6e-78 263.8 0.1 1.5e-64 218.5 0.1 2.0 2 0 0 2 2 2 2 Amidase Apc3 PF12895.2 OAJ08285.1 - 4.2e-09 36.4 6.0 0.11 12.6 0.1 5.3 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 OAJ08285.1 - 4.4e-09 36.1 30.3 0.0013 18.5 0.9 7.1 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ08285.1 - 2.2e-07 30.4 15.6 0.0015 18.1 0.1 6.5 6 0 0 6 6 6 2 TPR repeat TPR_14 PF13428.1 OAJ08285.1 - 9.2e-07 28.9 29.5 0.31 11.8 0.2 9.0 10 1 0 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ08285.1 - 2.2e-05 24.9 25.5 0.0057 17.3 4.0 6.3 6 3 1 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ08285.1 - 6.1e-05 22.6 29.3 1.5 8.8 0.7 9.3 11 0 0 11 11 11 2 Tetratricopeptide repeat Apc5 PF12862.2 OAJ08285.1 - 0.002 17.8 9.8 1.6 8.5 0.4 5.1 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 5 CK_II_beta PF01214.13 OAJ08285.1 - 0.028 13.9 0.0 0.077 12.4 0.0 1.7 1 0 0 1 1 1 0 Casein kinase II regulatory subunit TPR_1 PF00515.23 OAJ08285.1 - 0.45 10.2 17.8 0.9 9.2 0.0 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat YfdX PF10938.3 OAJ08285.1 - 0.63 9.6 4.5 0.6 9.7 0.0 3.1 4 0 0 4 4 4 0 YfdX protein TPR_4 PF07721.9 OAJ08285.1 - 6.3 7.5 34.6 0.38 11.3 0.7 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ08285.1 - 8.3 7.1 17.0 83 3.9 0.1 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat PBP1_TM PF14812.1 OAJ08286.1 - 0.89 9.9 11.4 0.11 12.8 4.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Polysacc_deac_1 PF01522.16 OAJ08288.1 - 3.8e-05 23.3 0.0 5.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase MULE PF10551.4 OAJ08297.1 - 7.4e-12 45.2 0.0 1.7e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 OAJ08297.1 - 1.1e-06 29.0 0.9 2.3e-06 28.0 0.3 1.7 2 0 0 2 2 2 1 FAR1 DNA-binding domain RVT_1 PF00078.22 OAJ08300.1 - 8.1e-19 67.8 0.0 1.4e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08300.1 - 3e-15 56.3 0.0 8.2e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ08300.1 - 0.00074 19.9 0.0 0.0019 18.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ08300.1 - 0.0063 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ08300.1 - 0.023 14.5 0.1 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Flavokinase PF01687.12 OAJ08303.1 - 4e-35 120.4 0.0 5.6e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase Metallophos PF00149.23 OAJ08304.1 - 3.4e-07 29.8 2.4 2.9e-06 26.8 0.3 2.5 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase MCM PF00493.18 OAJ08307.1 - 5.9e-19 68.0 0.0 8.4e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Ribosomal_L3 PF00297.17 OAJ08308.1 - 3.4e-120 400.3 4.9 4.2e-120 400.0 3.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DUF3619 PF12279.3 OAJ08311.1 - 0.089 12.8 0.2 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Cytadhesin_P30 PF07271.6 OAJ08311.1 - 0.097 11.9 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF390 PF04094.9 OAJ08311.1 - 0.11 10.5 7.3 0.13 10.3 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Dicty_REP PF05086.7 OAJ08311.1 - 0.38 8.4 1.6 0.39 8.4 1.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein API5 PF05918.6 OAJ08312.1 - 0.024 13.1 0.3 0.026 13.0 0.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Utp11 PF03998.8 OAJ08312.1 - 0.024 14.4 0.1 0.026 14.3 0.1 1.1 1 0 0 1 1 1 0 Utp11 protein rve PF00665.21 OAJ08317.1 - 4.9e-20 71.8 0.0 8.2e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ08317.1 - 0.0013 18.2 0.2 0.0036 16.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain CIAPIN1 PF05093.8 OAJ08318.1 - 8.4e-31 106.0 3.5 1.9e-30 104.8 2.4 1.6 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis HsbA PF12296.3 OAJ08324.1 - 1.4e-14 54.0 13.1 2.2e-14 53.3 9.1 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A FUN14 PF04930.10 OAJ08324.1 - 0.7 10.1 4.3 3.5 7.9 2.9 2.3 1 1 0 1 1 1 0 FUN14 family Glyco_tranf_2_3 PF13641.1 OAJ08334.1 - 4.4e-26 92.0 0.0 5.8e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 OAJ08334.1 - 8.1e-21 74.6 4.7 8.1e-21 74.6 3.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 OAJ08334.1 - 9.9e-11 41.2 0.0 1.5e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 OAJ08334.1 - 1.3e-06 28.2 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 OAJ08334.1 - 0.064 12.3 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Ribosomal_L29e PF01779.12 OAJ08335.1 - 1.4e-08 34.4 0.6 2.3e-08 33.7 0.4 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family rve PF00665.21 OAJ08338.1 - 3.3e-15 56.2 0.0 7.1e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ08338.1 - 1.1e-14 54.2 0.0 2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) An_peroxidase PF03098.10 OAJ08343.1 - 1.8e-73 247.7 0.0 3.1e-56 190.8 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase DUF106 PF01956.11 OAJ08344.1 - 1.9e-57 193.4 0.8 2.3e-57 193.1 0.6 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 Cwf_Cwc_15 PF04889.7 OAJ08345.1 - 6e-67 225.9 16.6 7e-67 225.6 11.5 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop53 PF07767.6 OAJ08345.1 - 0.12 11.3 21.0 0.052 12.5 8.3 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) SGT1 PF07093.6 OAJ08345.1 - 2.2 6.5 20.3 2.7 6.2 14.1 1.1 1 0 0 1 1 1 0 SGT1 protein Histone PF00125.19 OAJ08350.1 - 3.5e-20 71.9 0.1 5.3e-20 71.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SPRY PF00622.23 OAJ08354.1 - 4e-18 65.6 0.2 6.8e-18 64.9 0.2 1.4 1 0 0 1 1 1 1 SPRY domain SPA PF08616.5 OAJ08354.1 - 0.23 11.1 0.1 0.45 10.2 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis GCR1_C PF12550.3 OAJ08366.1 - 3.8e-09 36.2 0.6 3.8e-09 36.2 0.4 1.8 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Daxx PF03344.10 OAJ08368.1 - 0.013 13.9 1.5 0.032 12.7 1.0 1.5 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 OAJ08368.1 - 0.26 11.5 8.8 0.69 10.1 6.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 OAJ08368.1 - 1.7 8.1 6.8 3.8 6.9 4.7 1.5 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 OAJ08368.1 - 2.1 6.1 6.2 3.7 5.3 4.3 1.3 1 0 0 1 1 1 0 Nop14-like family RAI16-like PF10257.4 OAJ08371.1 - 1.2e-57 195.4 0.0 5e-57 193.4 0.0 1.9 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein Sigma70_ner PF04546.8 OAJ08371.1 - 1.5 8.4 2.8 23 4.5 0.1 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Hydant_A_N PF05378.8 OAJ08376.1 - 2.5e-18 66.2 0.0 3.1e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region Glyco_tran_28_C PF04101.11 OAJ08377.1 - 8.3e-23 80.8 0.0 1.3e-22 80.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Mo25 PF08569.6 OAJ08378.1 - 1.1e-116 389.5 0.7 2e-109 365.7 2.8 2.6 1 1 1 2 2 2 2 Mo25-like HEAT_2 PF13646.1 OAJ08378.1 - 0.024 14.8 0.0 0.56 10.5 0.0 2.8 3 0 0 3 3 3 0 HEAT repeats RepA_N PF06970.6 OAJ08378.1 - 0.47 10.2 3.6 0.19 11.5 0.6 1.8 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus Sporozoite_P67 PF05642.6 OAJ08378.1 - 2.6 5.8 18.3 4.2 5.1 12.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Amidohydro_4 PF13147.1 OAJ08383.1 - 4.8e-09 36.6 3.0 9.3e-08 32.4 0.4 2.2 1 1 0 2 2 2 2 Amidohydrolase Amidohydro_2 PF04909.9 OAJ08383.1 - 5.6e-06 26.1 0.9 1.3e-05 24.9 0.3 2.0 1 1 1 2 2 2 1 Amidohydrolase HALZ PF02183.13 OAJ08386.1 - 0.0069 16.0 0.8 0.0069 16.0 0.5 4.2 3 2 1 4 4 4 2 Homeobox associated leucine zipper Orthopox_A5L PF06193.6 OAJ08386.1 - 0.0088 15.9 8.7 0.37 10.6 6.0 2.3 1 1 0 1 1 1 1 Orthopoxvirus A5L protein-like CENP-F_leu_zip PF10473.4 OAJ08386.1 - 0.011 15.5 30.2 0.36 10.6 6.6 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 OAJ08386.1 - 0.029 14.1 35.0 0.06 13.0 16.3 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Erythro-docking PF09277.6 OAJ08386.1 - 0.034 13.8 0.5 0.097 12.3 0.4 1.8 1 0 0 1 1 1 0 Erythronolide synthase, docking TBD PF12845.2 OAJ08386.1 - 0.039 13.5 1.5 0.039 13.5 1.1 2.8 3 0 0 3 3 3 0 TBD domain AAA_13 PF13166.1 OAJ08386.1 - 0.053 11.9 13.2 0.063 11.7 9.2 1.1 1 0 0 1 1 1 0 AAA domain TraF_2 PF13729.1 OAJ08386.1 - 0.12 11.1 0.9 0.2 10.4 0.6 1.6 1 1 0 1 1 1 0 F plasmid transfer operon, TraF, protein Peptidase_S49 PF01343.13 OAJ08386.1 - 0.18 11.6 7.6 0.3 10.8 4.2 1.9 1 1 1 2 2 2 0 Peptidase family S49 Mnd1 PF03962.10 OAJ08386.1 - 0.31 10.6 28.2 0.59 9.7 6.2 2.5 1 1 2 3 3 3 0 Mnd1 family ApoO PF09769.4 OAJ08386.1 - 0.32 10.7 3.7 0.3 10.7 0.4 2.1 1 1 1 2 2 2 0 Apolipoprotein O KaiC PF06745.8 OAJ08386.1 - 0.42 9.6 5.3 0.12 11.5 1.2 1.7 1 1 0 2 2 2 0 KaiC FUSC PF04632.7 OAJ08386.1 - 0.71 8.2 14.1 0.9 7.8 9.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Reo_sigmaC PF04582.7 OAJ08386.1 - 0.74 8.9 5.4 1.6 7.8 3.5 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein COG5 PF10392.4 OAJ08386.1 - 1.1 9.2 12.1 0.18 11.7 4.5 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Mt_ATP-synt_B PF05405.9 OAJ08386.1 - 1.2 8.5 22.5 0.13 11.6 7.6 2.1 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF479 PF04336.7 OAJ08386.1 - 1.7 8.8 6.6 0.31 11.1 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF479 GAS PF13851.1 OAJ08386.1 - 2.1 7.4 26.3 0.38 9.9 10.9 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 OAJ08386.1 - 2.5 7.9 33.0 0.16 11.7 10.4 2.3 1 1 1 2 2 2 0 Tropomyosin like DUF3347 PF11827.3 OAJ08386.1 - 2.9 7.8 16.4 0.12 12.3 4.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) DUF3584 PF12128.3 OAJ08386.1 - 3.5 4.8 29.7 4 4.6 20.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) VPS11_C PF12451.3 OAJ08386.1 - 3.6 7.5 5.8 26 4.7 0.3 2.9 2 1 1 3 3 3 0 Vacuolar protein sorting protein 11 C terminal DASH_Dam1 PF08653.5 OAJ08386.1 - 4.4 7.1 7.5 2.4 7.9 0.1 3.4 3 1 2 5 5 4 0 DASH complex subunit Dam1 DNA_topoisoIV PF00521.15 OAJ08386.1 - 4.8 5.9 10.6 6.1 5.5 7.3 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF87 PF01935.12 OAJ08386.1 - 5.3 6.8 11.5 1.1 9.0 4.1 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF87 Ax_dynein_light PF10211.4 OAJ08386.1 - 6 6.6 26.9 0.6 9.9 7.2 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain DUF972 PF06156.8 OAJ08386.1 - 7 7.0 20.4 8.6 6.7 4.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Cupin_4 PF08007.7 OAJ08386.1 - 8.8 5.4 13.4 1.5 8.0 2.3 2.0 1 1 1 2 2 2 0 Cupin superfamily protein IncA PF04156.9 OAJ08386.1 - 8.9 5.8 34.2 12 5.4 15.7 2.1 1 1 1 2 2 2 0 IncA protein Exonuc_VII_L PF02601.10 OAJ08386.1 - 9.2 5.3 14.3 13 4.8 9.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ank_2 PF12796.2 OAJ08387.1 - 2.6e-21 75.7 1.5 1.3e-09 38.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ08387.1 - 5.1e-17 60.7 14.1 3.1e-07 29.8 0.7 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 OAJ08387.1 - 3.8e-13 49.5 4.0 0.00023 21.6 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ08387.1 - 6.7e-12 45.2 5.1 2.5e-06 27.5 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ08387.1 - 2e-10 39.8 5.3 0.00091 19.2 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat BAF1_ABF1 PF04684.8 OAJ08387.1 - 1.9 7.2 16.2 2.9 6.6 11.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1777 PF08648.7 OAJ08387.1 - 2.6 7.7 9.3 3.2 7.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Serinc PF03348.10 OAJ08387.1 - 2.7 6.6 4.6 3.9 6.0 3.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Porin_3 PF01459.17 OAJ08390.1 - 9.3e-59 198.9 0.1 1.1e-58 198.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Esterase PF00756.15 OAJ08400.1 - 0.00033 20.1 0.0 0.00052 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 OAJ08400.1 - 0.0087 15.8 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF605 PF04652.11 OAJ08400.1 - 0.52 9.6 14.8 0.74 9.1 10.2 1.2 1 0 0 1 1 1 0 Vta1 like YchF-GTPase_C PF06071.8 OAJ08402.1 - 9.1e-35 118.3 0.1 2.4e-34 116.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 OAJ08402.1 - 1.8e-13 50.4 0.0 5.2e-13 48.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ08402.1 - 8.9e-06 25.0 0.0 1.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Zip PF02535.17 OAJ08403.1 - 1.4e-51 175.4 9.0 1.7e-51 175.1 6.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter RNA_pol_3_Rpc31 PF11705.3 OAJ08410.1 - 0.0047 16.8 1.8 0.0047 16.8 1.2 2.5 2 1 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 PI3K_1B_p101 PF10486.4 OAJ08410.1 - 0.02 12.5 5.2 0.025 12.1 3.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Cwf_Cwc_15 PF04889.7 OAJ08410.1 - 0.49 10.0 26.7 1.8 8.2 7.3 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Voldacs PF03517.8 OAJ08410.1 - 0.57 10.0 9.5 1.6 8.5 0.6 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling PCEMA1 PF07418.6 OAJ08410.1 - 0.79 9.0 9.3 0.93 8.7 1.6 2.0 2 0 0 2 2 2 0 Acidic phosphoprotein precursor PCEMA1 ANAPC15 PF15243.1 OAJ08410.1 - 1.2 9.2 21.4 1.7 8.7 3.2 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 RXT2_N PF08595.6 OAJ08410.1 - 2.2 8.0 16.2 1.1 8.9 0.8 2.5 3 0 0 3 3 3 0 RXT2-like, N-terminal Nop14 PF04147.7 OAJ08410.1 - 3.5 5.4 24.9 5.1 4.8 17.3 1.3 1 1 0 1 1 1 0 Nop14-like family Nucleo_P87 PF07267.6 OAJ08410.1 - 5 5.6 11.5 0.58 8.7 2.7 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 CENP-B_dimeris PF09026.5 OAJ08410.1 - 9.3 6.5 33.1 0.23 11.7 4.5 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DIM PF08194.7 OAJ08411.1 - 0.62 10.0 3.6 1.7 8.6 0.1 2.5 2 0 0 2 2 2 0 DIM protein KAAG1 PF15354.1 OAJ08412.1 - 0.053 13.8 0.6 0.1 12.9 0.4 1.5 1 0 0 1 1 1 0 Kidney-associated antigen 1 MBOAT PF03062.14 OAJ08415.1 - 4.9e-41 140.9 0.0 2.2e-40 138.7 0.0 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family RNase_T PF00929.19 OAJ08416.1 - 4.6e-07 30.2 0.0 2.5e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Exonuclease Adeno_E3_CR2 PF02439.10 OAJ08425.1 - 0.46 10.0 2.2 0.53 9.8 1.5 1.1 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pox_P21 PF05313.7 OAJ08425.1 - 0.9 8.7 6.4 0.95 8.6 4.4 1.0 1 0 0 1 1 1 0 Poxvirus P21 membrane protein PGM_PMM_I PF02878.11 OAJ08428.1 - 2.2e-36 124.4 0.1 3.3e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 OAJ08428.1 - 1.8e-27 95.5 0.0 4.6e-27 94.3 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 OAJ08428.1 - 1.5e-14 54.1 0.0 4.4e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 OAJ08428.1 - 2e-09 37.3 0.0 7.1e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain mRNA_cap_enzyme PF01331.14 OAJ08429.1 - 4e-48 163.6 0.3 5.3e-48 163.2 0.2 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 OAJ08429.1 - 4.2e-14 52.7 0.0 5.1e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 OAJ08429.1 - 1.1e-07 31.4 0.1 2.9e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain FHA PF00498.21 OAJ08432.1 - 0.014 15.4 0.1 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 FHA domain CRPA PF05745.6 OAJ08439.1 - 0.25 11.1 1.5 0.44 10.3 1.0 1.4 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Claudin_2 PF13903.1 OAJ08439.1 - 0.76 9.4 5.6 2.4 7.7 0.0 2.6 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2029 PF09594.5 OAJ08440.1 - 0.016 14.7 2.4 1.3 8.4 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2029) Claudin_2 PF13903.1 OAJ08440.1 - 0.022 14.4 1.2 0.03 14.0 0.5 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF3648 PF12364.3 OAJ08440.1 - 0.093 12.7 0.0 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3648) DUF4013 PF13197.1 OAJ08440.1 - 0.13 11.5 6.9 0.43 9.9 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4013) MARVEL PF01284.18 OAJ08440.1 - 0.15 11.8 4.3 0.24 11.2 2.9 1.4 1 1 0 1 1 1 0 Membrane-associating domain FA_desaturase PF00487.19 OAJ08440.1 - 3.4 7.0 8.0 0.96 8.8 3.4 1.6 1 1 1 2 2 2 0 Fatty acid desaturase PIF1 PF05970.9 OAJ08441.1 - 2.1e-46 158.5 0.0 1.6e-45 155.6 0.0 2.1 1 1 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ08441.1 - 3.2e-29 101.9 0.1 6.4e-29 100.9 0.1 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 OAJ08441.1 - 3.3e-07 30.0 0.0 1e-06 28.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 OAJ08441.1 - 0.0018 17.9 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 OAJ08441.1 - 0.0019 17.9 0.0 0.022 14.4 0.1 2.4 2 0 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.13 OAJ08441.1 - 0.008 15.7 0.2 1.8 8.0 0.1 3.0 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 OAJ08441.1 - 0.0091 15.0 0.0 0.068 12.1 0.0 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 OAJ08441.1 - 0.017 14.0 0.0 0.037 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 OAJ08441.1 - 0.023 14.7 0.6 0.21 11.5 0.2 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 OAJ08441.1 - 0.023 14.4 0.1 0.068 12.9 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 OAJ08441.1 - 0.024 14.7 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 OAJ08441.1 - 0.07 12.8 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.10 OAJ08441.1 - 0.13 12.1 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 OAJ08441.1 - 0.14 11.6 0.0 0.35 10.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.9 OAJ08441.1 - 0.5 8.0 0.0 3.5 5.2 0.0 2.0 2 0 0 2 2 2 0 Helicase RVT_1 PF00078.22 OAJ08443.1 - 5.9e-20 71.5 0.0 1.2e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08445.1 - 1.2e-13 51.1 0.0 2.5e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain LIM PF00412.17 OAJ08451.1 - 1.6e-34 117.7 25.2 7.8e-14 51.4 4.3 5.1 5 0 0 5 5 5 5 LIM domain zf-DNA_Pol PF08996.5 OAJ08451.1 - 7.6 5.8 12.0 0.46 9.8 0.6 3.1 3 1 1 4 4 4 0 DNA Polymerase alpha zinc finger MARVEL PF01284.18 OAJ08452.1 - 3.4e-12 46.4 9.5 4.5e-12 46.0 6.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4064 PF13273.1 OAJ08452.1 - 0.23 11.5 8.6 0.49 10.5 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Snf7 PF03357.16 OAJ08453.1 - 7e-30 103.6 18.6 7e-30 103.6 12.9 1.3 1 1 0 1 1 1 1 Snf7 DUF2428 PF10350.4 OAJ08453.1 - 0.048 12.6 0.5 0.08 11.9 0.4 1.3 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Vac14_Fig4_bd PF11916.3 OAJ08459.1 - 5.6e-74 247.2 7.2 7.4e-74 246.8 3.8 2.0 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 OAJ08459.1 - 2.4e-46 156.0 0.0 2.4e-41 140.0 0.0 4.0 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 OAJ08459.1 - 2.2e-17 61.5 3.4 5.6e-05 22.8 0.0 8.0 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 OAJ08459.1 - 1.9e-09 37.6 7.0 0.26 11.6 0.3 5.8 4 1 1 5 5 5 4 HEAT repeats Cnd1 PF12717.2 OAJ08459.1 - 9.9e-05 22.2 1.3 1.2 8.9 0.0 4.0 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 OAJ08459.1 - 0.00028 20.8 0.5 0.081 12.8 0.1 3.1 4 0 0 4 4 4 1 Parkin co-regulated protein HEAT_EZ PF13513.1 OAJ08459.1 - 0.0014 19.0 11.6 0.06 13.8 0.0 7.1 7 1 1 8 8 8 1 HEAT-like repeat CLASP_N PF12348.3 OAJ08459.1 - 0.0021 17.4 0.2 4.5 6.5 0.0 4.0 3 1 1 4 4 4 1 CLASP N terminal Dopey_N PF04118.9 OAJ08459.1 - 0.066 11.9 0.3 1.3 7.7 0.0 2.7 2 1 1 3 3 3 0 Dopey, N-terminal Adaptin_N PF01602.15 OAJ08459.1 - 0.54 8.5 2.8 12 4.0 0.4 2.8 2 1 1 3 3 3 0 Adaptin N terminal region Arm PF00514.18 OAJ08459.1 - 0.76 9.7 5.6 6.8 6.6 0.0 5.2 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Brr6_like_C_C PF10104.4 OAJ08464.1 - 1e-06 28.3 0.0 1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF3693 PF12472.3 OAJ08464.1 - 3.1 7.4 5.7 10 5.7 0.7 2.3 2 0 0 2 2 2 0 Phage related protein Ribosomal_L2_C PF03947.13 OAJ08469.1 - 5.1e-44 149.2 5.6 4.6e-32 110.5 3.3 2.6 1 1 1 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 OAJ08469.1 - 1.2e-25 89.2 0.0 2.2e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PrpF PF04303.8 OAJ08470.1 - 8.5e-48 162.9 0.2 1.2e-33 116.3 0.0 2.5 2 1 0 2 2 2 2 PrpF protein Peptidase_S8 PF00082.17 OAJ08474.1 - 7.4e-25 87.6 0.1 1.1e-24 87.0 0.1 1.2 1 0 0 1 1 1 1 Subtilase family RVT_1 PF00078.22 OAJ08478.1 - 4.6e-17 62.0 0.0 1.1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08478.1 - 2.9e-14 53.2 0.0 1.5e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Prefoldin_2 PF01920.15 OAJ08481.1 - 5.2e-23 80.8 0.6 6.2e-23 80.5 0.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.10 OAJ08481.1 - 5.5e-05 22.5 2.2 0.083 12.3 0.0 2.2 1 1 1 2 2 2 2 Septum formation initiator FTA4 PF13093.1 OAJ08481.1 - 0.0011 18.5 0.2 0.0013 18.2 0.2 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 ADIP PF11559.3 OAJ08481.1 - 0.0068 16.3 1.5 2.5 8.0 0.0 2.1 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding Spc24 PF08286.6 OAJ08481.1 - 0.016 14.8 5.7 0.62 9.7 1.3 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin PF02996.12 OAJ08481.1 - 0.024 14.2 0.9 0.069 12.8 0.6 1.6 1 1 0 1 1 1 0 Prefoldin subunit Atg14 PF10186.4 OAJ08481.1 - 0.03 13.2 0.2 0.038 12.9 0.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NIT PF08376.5 OAJ08481.1 - 0.033 13.7 0.3 0.083 12.4 0.1 1.6 2 0 0 2 2 2 0 Nitrate and nitrite sensing STAT_alpha PF01017.15 OAJ08481.1 - 0.057 13.1 1.3 0.3 10.7 0.9 1.9 1 1 0 1 1 1 0 STAT protein, all-alpha domain TMF_DNA_bd PF12329.3 OAJ08481.1 - 0.059 13.1 1.6 1.5 8.6 0.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 OAJ08481.1 - 0.069 13.0 1.1 1.1 9.1 0.1 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) PEP-utilisers_N PF05524.8 OAJ08481.1 - 0.087 12.6 0.7 0.84 9.4 0.0 2.0 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF869 PF05911.6 OAJ08481.1 - 0.096 10.9 2.8 0.38 8.9 0.1 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) Seryl_tRNA_N PF02403.17 OAJ08481.1 - 0.12 12.3 2.3 3.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4164 PF13747.1 OAJ08481.1 - 0.17 12.0 4.6 3.1 7.9 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TPR_MLP1_2 PF07926.7 OAJ08481.1 - 0.19 11.4 1.8 7 6.4 0.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF465 PF04325.8 OAJ08481.1 - 0.32 10.7 2.9 1.7 8.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF465) CCDC-167 PF15188.1 OAJ08481.1 - 0.4 10.6 3.0 6.6 6.7 0.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 HalX PF08663.5 OAJ08481.1 - 0.53 10.2 5.1 0.31 11.0 1.1 2.2 2 0 0 2 2 2 0 HalX domain Cytadhesin_P30 PF07271.6 OAJ08482.1 - 2.3 7.4 4.5 3.2 6.9 3.1 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 CoA_binding PF02629.14 OAJ08483.1 - 1.1e-28 99.5 1.9 3e-27 94.9 0.1 2.5 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 OAJ08483.1 - 1e-19 70.6 0.6 2.2e-19 69.5 0.4 1.6 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 OAJ08483.1 - 8.7e-09 35.1 0.1 1.9e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 OAJ08483.1 - 7.9e-05 22.8 0.0 0.00042 20.4 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 OAJ08483.1 - 0.0025 18.3 0.0 0.0065 16.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF3844 PF12955.2 OAJ08484.1 - 7.6e-26 90.2 0.2 1.4e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 OAJ08484.1 - 0.17 12.0 2.8 0.37 11.0 1.9 1.5 1 0 0 1 1 1 0 EGF-like domain DDE_Tnp_4 PF13359.1 OAJ08488.1 - 2.1e-30 105.4 0.0 2.9e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ08488.1 - 1.4e-07 31.1 0.0 1.7e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.16 OAJ08488.1 - 0.00024 20.7 0.0 0.00088 18.8 0.0 1.9 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.1 OAJ08488.1 - 0.0015 18.7 0.3 0.0044 17.1 0.0 1.8 2 0 0 2 2 2 1 Transposase DDE domain Myb_DNA-bind_3 PF12776.2 OAJ08489.1 - 4.4e-13 49.6 0.5 7.7e-13 48.9 0.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ08489.1 - 3.8e-05 23.7 1.4 0.00042 20.3 1.0 2.2 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain PBP1_TM PF14812.1 OAJ08493.1 - 0.21 11.9 9.7 0.23 11.7 1.7 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 OAJ08493.1 - 4.4 7.0 7.6 1.3 8.8 0.8 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal TRAM_LAG1_CLN8 PF03798.11 OAJ08494.1 - 6.1e-10 38.9 1.2 6.1e-10 38.9 0.8 1.5 2 0 0 2 2 2 1 TLC domain E1-E2_ATPase PF00122.15 OAJ08497.1 - 5.9e-49 166.1 1.3 9.3e-49 165.5 0.9 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 OAJ08497.1 - 2.1e-39 136.1 0.2 2.9e-32 112.8 0.0 3.6 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase HMA PF00403.21 OAJ08497.1 - 5.8e-17 61.5 0.0 8.2e-10 38.6 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 OAJ08497.1 - 1.4e-13 51.4 0.0 1.4e-12 48.1 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ08497.1 - 0.016 14.8 0.4 0.07 12.7 0.4 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Aminotran_3 PF00202.16 OAJ08502.1 - 3.2e-77 259.6 0.0 4.5e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DAO PF01266.19 OAJ08503.1 - 2e-47 161.8 2.1 2.3e-47 161.6 1.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAJ08503.1 - 7.9e-07 29.3 0.1 0.004 17.5 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAJ08503.1 - 0.00023 21.0 1.2 0.00073 19.5 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 OAJ08503.1 - 0.0079 15.3 0.1 0.02 13.9 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 OAJ08503.1 - 0.014 15.2 0.1 0.06 13.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 OAJ08503.1 - 0.043 12.4 0.3 0.43 9.1 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Chlam_vir PF05475.6 OAJ08504.1 - 0.085 11.9 1.6 0.14 11.2 1.1 1.3 1 1 0 1 1 1 0 Chlamydia virulence protein PGP3-D NUDE_C PF04880.8 OAJ08504.1 - 1.9 8.8 7.1 2.2 8.6 4.9 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Sporozoite_P67 PF05642.6 OAJ08504.1 - 3.7 5.2 13.9 4 5.1 9.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Clathrin_propel PF01394.15 OAJ08507.1 - 2.5e-22 77.5 7.4 3e-05 24.0 0.1 5.6 5 1 0 5 5 5 4 Clathrin propeller repeat Cactin_mid PF10312.4 OAJ08507.1 - 0.052 12.7 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Conserved mid region of cactin AAA PF00004.24 OAJ08509.1 - 5.8e-43 146.2 0.0 9.6e-43 145.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAJ08509.1 - 2.5e-07 30.5 0.1 3.4e-06 26.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 OAJ08509.1 - 5.5e-07 29.7 0.1 3e-05 24.0 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 OAJ08509.1 - 1.3e-06 28.4 0.0 9.4e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 OAJ08509.1 - 2.8e-06 27.4 0.1 0.0012 19.0 0.0 2.7 2 1 1 3 3 2 1 AAA domain RuvB_N PF05496.7 OAJ08509.1 - 1.1e-05 24.5 0.0 2.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 OAJ08509.1 - 6.1e-05 22.7 0.1 0.0002 21.0 0.1 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_17 PF13207.1 OAJ08509.1 - 0.00032 21.4 0.9 0.0012 19.6 0.2 2.4 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 OAJ08509.1 - 0.00093 18.1 0.0 0.0019 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 OAJ08509.1 - 0.0023 17.8 0.0 0.0054 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 OAJ08509.1 - 0.0029 16.7 0.0 0.006 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 OAJ08509.1 - 0.0033 16.8 0.0 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 OAJ08509.1 - 0.0034 16.1 0.0 0.0059 15.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 OAJ08509.1 - 0.0037 17.1 0.0 0.0077 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ08509.1 - 0.0042 17.3 0.2 0.022 15.0 0.0 2.3 2 1 0 3 3 2 1 AAA domain DUF4200 PF13863.1 OAJ08509.1 - 0.0063 16.4 0.3 0.0063 16.4 0.2 1.7 2 0 0 2 2 1 1 Domain of unknown function (DUF4200) AAA_28 PF13521.1 OAJ08509.1 - 0.0071 16.3 0.1 0.021 14.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 OAJ08509.1 - 0.0078 15.6 0.2 0.041 13.2 0.1 2.1 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.21 OAJ08509.1 - 0.0087 15.5 0.0 0.032 13.6 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 OAJ08509.1 - 0.0089 15.1 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 OAJ08509.1 - 0.0098 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 OAJ08509.1 - 0.011 15.3 0.1 0.028 14.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 OAJ08509.1 - 0.011 15.5 0.0 0.039 13.7 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 OAJ08509.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 OAJ08509.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.1 OAJ08509.1 - 0.032 13.8 0.4 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 OAJ08509.1 - 0.042 12.9 0.1 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 KaiC UPF0079 PF02367.12 OAJ08509.1 - 0.044 13.4 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 OAJ08509.1 - 0.051 12.4 0.0 0.084 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 OAJ08509.1 - 0.072 12.7 0.0 0.37 10.4 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase NACHT PF05729.7 OAJ08509.1 - 0.073 12.7 0.0 0.21 11.2 0.0 1.8 1 1 1 2 2 2 0 NACHT domain CPT PF07931.7 OAJ08509.1 - 0.089 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.1 OAJ08509.1 - 0.11 12.8 3.7 4.2 7.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain Sec23_trunk PF04811.10 OAJ08512.1 - 7.6e-71 238.3 0.0 1.2e-70 237.6 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.10 OAJ08512.1 - 5.6e-17 61.0 7.9 1.1e-16 60.1 5.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 OAJ08512.1 - 3e-16 58.7 0.2 7.1e-16 57.5 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 OAJ08512.1 - 1.2e-15 57.7 0.0 3.4e-15 56.3 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain RVT_1 PF00078.22 OAJ08514.1 - 1.8e-19 69.9 0.0 3.2e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08514.1 - 3.4e-13 49.7 0.0 9.4e-13 48.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ08514.1 - 0.0022 18.4 0.0 0.0058 17.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ08514.1 - 0.054 13.4 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ08514.1 - 0.087 12.6 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4131 PF13567.1 OAJ08516.1 - 0.95 8.8 4.6 0.34 10.3 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Phage_integrase PF00589.17 OAJ08520.1 - 0.00054 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Dak2 PF02734.12 OAJ08525.1 - 0.015 14.9 0.5 0.049 13.2 0.1 1.9 2 0 0 2 2 2 0 DAK2 domain MAT_Alpha1 PF04769.7 OAJ08525.1 - 0.067 12.5 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 DUF3008 PF11450.3 OAJ08525.1 - 0.074 13.1 0.2 4.7 7.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) Methyltransf_11 PF08241.7 OAJ08529.1 - 4.2e-09 36.7 0.0 2.9e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ08529.1 - 3.7e-06 27.4 0.0 5.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ08529.1 - 1.6e-05 25.2 0.0 0.0058 17.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ08529.1 - 0.00013 22.2 0.0 0.00037 20.7 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ08529.1 - 0.0013 18.7 0.0 0.0044 17.0 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ08529.1 - 0.0022 17.7 0.0 0.0026 17.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ08529.1 - 0.0032 17.0 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain FHA PF00498.21 OAJ08530.1 - 0.038 14.0 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 FHA domain RVT_1 PF00078.22 OAJ08533.1 - 4.4e-09 36.0 0.0 1.3e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 OAJ08533.1 - 0.0076 16.1 1.2 0.015 15.1 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.1 OAJ08533.1 - 0.016 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 OAJ08533.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease gag_pre-integrs PF13976.1 OAJ08534.1 - 0.043 13.4 0.1 2.6 7.7 0.0 2.8 3 0 0 3 3 3 0 GAG-pre-integrase domain APO_RNA-bind PF05634.6 OAJ08534.1 - 0.12 11.5 0.3 9.3 5.3 0.1 2.1 2 0 0 2 2 2 0 APO RNA-binding zf-H2C2 PF09337.5 OAJ08534.1 - 0.18 11.2 0.5 0.31 10.4 0.4 1.4 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger BIR PF00653.16 OAJ08548.1 - 1.5e-26 92.5 1.9 7.2e-19 67.9 1.2 2.9 2 1 0 2 2 2 2 Inhibitor of Apoptosis domain Tfb4 PF03850.9 OAJ08548.1 - 1 8.5 6.3 2.2 7.4 4.4 1.5 1 0 0 1 1 1 0 Transcription factor Tfb4 Mem_trans PF03547.13 OAJ08548.1 - 5.5 5.1 4.5 7.6 4.7 3.1 1.3 1 0 0 1 1 1 0 Membrane transport protein Ycf1 PF05758.7 OAJ08548.1 - 5.6 4.5 20.0 9.3 3.8 13.9 1.3 1 0 0 1 1 1 0 Ycf1 UMP1 PF05348.6 OAJ08550.1 - 3.9e-18 65.6 0.7 4.8e-18 65.3 0.5 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 LepA_C PF06421.7 OAJ08553.1 - 0.089 12.7 0.3 0.089 12.7 0.2 1.8 2 1 0 2 2 2 0 GTP-binding protein LepA C-terminus DUF3435 PF11917.3 OAJ08553.1 - 0.59 8.7 6.8 0.77 8.4 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Herpes_UL3 PF03369.8 OAJ08553.1 - 0.78 9.7 3.6 4 7.4 0.7 2.2 1 1 0 2 2 2 0 Herpesvirus UL3 protein S4_2 PF13275.1 OAJ08554.1 - 0.054 13.0 0.1 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 S4 domain FHA PF00498.21 OAJ08554.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 FHA domain SPT2 PF08243.6 OAJ08558.1 - 0.061 13.6 23.2 0.2 11.9 16.1 1.9 1 1 0 1 1 1 0 SPT2 chromatin protein Herpes_UL32 PF06070.6 OAJ08558.1 - 6.2 5.1 28.8 8.2 4.7 20.0 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 FYVE PF01363.16 OAJ08560.1 - 5.5e-15 55.0 8.8 7.3e-15 54.6 6.1 1.2 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 OAJ08560.1 - 0.019 14.8 7.5 0.045 13.6 5.2 1.5 1 1 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.2 OAJ08560.1 - 0.067 13.0 7.4 0.64 9.8 0.2 2.5 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.1 OAJ08560.1 - 0.29 10.9 6.1 0.46 10.2 2.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Cript PF10235.4 OAJ08560.1 - 1.8 8.9 4.7 0.33 11.3 0.8 1.6 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT HypA PF01155.14 OAJ08560.1 - 2 8.1 7.9 1.6 8.4 2.3 2.3 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-B_box PF00643.19 OAJ08560.1 - 4.1 7.3 11.4 10 6.0 5.4 2.4 2 1 0 2 2 2 0 B-box zinc finger IBR PF01485.16 OAJ08560.1 - 7.7 6.4 10.4 8.8 6.2 5.3 2.1 2 1 0 2 2 2 0 IBR domain zf-RING_2 PF13639.1 OAJ08561.1 - 0.0028 17.4 0.3 0.0051 16.6 0.2 1.4 1 0 0 1 1 1 1 Ring finger domain DUF1525 PF07511.6 OAJ08561.1 - 0.022 14.7 0.1 7.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) MFS_1 PF07690.11 OAJ08566.1 - 1.7e-25 89.4 35.9 6.4e-17 61.2 9.1 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Utp12 PF04003.7 OAJ08570.1 - 0.069 13.0 0.4 0.069 13.0 0.3 1.4 2 0 0 2 2 2 0 Dip2/Utp12 Family Helicase_C PF00271.26 OAJ08571.1 - 1.2e-10 41.0 0.0 1.3e-08 34.5 0.0 2.9 3 1 0 3 3 3 1 Helicase conserved C-terminal domain Herpes_capsid PF06112.6 OAJ08571.1 - 0.078 13.0 7.8 0.14 12.2 5.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DELLA PF12041.3 OAJ08571.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal DEAD PF00270.24 OAJ08571.1 - 0.14 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase zf-DHHC PF01529.15 OAJ08574.1 - 4.6e-41 140.1 3.0 4.6e-41 140.1 2.1 2.4 3 1 1 4 4 4 1 DHHC palmitoyltransferase Spt4 PF06093.8 OAJ08574.1 - 0.38 10.6 3.1 0.94 9.4 2.2 1.7 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Voldacs PF03517.8 OAJ08575.1 - 1.6e-19 70.0 0.0 2.2e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling GRAM PF02893.15 OAJ08575.1 - 0.013 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 GRAM domain NOA36 PF06524.7 OAJ08575.1 - 0.29 10.3 3.1 0.36 10.0 2.1 1.1 1 0 0 1 1 1 0 NOA36 protein Skp1_POZ PF03931.10 OAJ08576.1 - 0.00032 20.7 0.0 0.00063 19.7 0.0 1.5 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain RVT_1 PF00078.22 OAJ08582.1 - 1.8e-15 56.8 0.0 3.9e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Elicitin PF00964.12 OAJ08591.1 - 0.44 10.5 4.6 2.3 8.2 3.2 1.8 1 1 0 1 1 1 0 Elicitin Calcipressin PF04847.7 OAJ08595.1 - 2e-26 92.6 0.0 1.7e-22 79.8 0.3 2.2 2 0 0 2 2 2 2 Calcipressin Septin PF00735.13 OAJ08596.1 - 2.8e-116 387.4 0.4 3.7e-116 387.0 0.3 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 OAJ08596.1 - 1.6e-08 34.4 0.0 4.1e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 OAJ08596.1 - 1.6e-07 30.6 0.0 4.1e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 OAJ08596.1 - 3.4e-07 29.8 0.8 9.9e-06 25.1 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.17 OAJ08596.1 - 4.6e-05 22.8 0.6 0.00015 21.2 0.4 1.8 1 1 0 1 1 1 1 Ras family AAA_10 PF12846.2 OAJ08596.1 - 0.00036 20.0 0.0 0.00076 18.9 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain AIG1 PF04548.11 OAJ08596.1 - 0.0004 19.5 0.0 0.00087 18.4 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 OAJ08596.1 - 0.00041 20.8 0.1 0.0015 19.0 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 OAJ08596.1 - 0.00069 19.2 0.6 0.0015 18.1 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ08596.1 - 0.00074 19.6 1.6 0.0051 16.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.4 OAJ08596.1 - 0.00099 18.6 2.0 0.017 14.6 0.4 2.9 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 OAJ08596.1 - 0.001 19.3 0.1 0.0034 17.6 0.0 1.9 2 0 0 2 2 2 1 ABC transporter Gtr1_RagA PF04670.7 OAJ08596.1 - 0.0011 18.1 0.1 0.0034 16.5 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 OAJ08596.1 - 0.0017 18.3 0.5 0.0067 16.4 0.0 2.2 3 0 0 3 3 3 1 AAA ATPase domain MobB PF03205.9 OAJ08596.1 - 0.0027 17.4 0.2 0.0074 15.9 0.1 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 OAJ08596.1 - 0.0094 15.7 6.1 0.35 10.6 0.2 2.8 2 1 1 3 3 3 2 Dynamin family NACHT PF05729.7 OAJ08596.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 OAJ08596.1 - 0.012 15.4 0.6 0.088 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 OAJ08596.1 - 0.014 14.9 0.8 2 7.8 0.1 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 OAJ08596.1 - 0.014 14.6 0.1 0.04 13.1 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_33 PF13671.1 OAJ08596.1 - 0.027 14.3 0.1 0.079 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 OAJ08596.1 - 0.04 14.2 0.5 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 OAJ08596.1 - 0.041 13.4 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pox_A32 PF04665.7 OAJ08596.1 - 0.053 12.8 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein SRPRB PF09439.5 OAJ08596.1 - 0.063 12.4 0.1 0.13 11.4 0.1 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RNA_helicase PF00910.17 OAJ08596.1 - 0.075 13.2 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 OAJ08596.1 - 0.076 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain cobW PF02492.14 OAJ08596.1 - 0.087 12.2 3.3 0.5 9.7 0.3 2.5 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 OAJ08596.1 - 0.1 12.0 1.2 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family CHCH PF06747.8 OAJ08597.1 - 1.1e-05 25.1 1.1 1.5e-05 24.7 0.8 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 OAJ08597.1 - 0.00024 20.7 0.5 0.00029 20.5 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.3 OAJ08597.1 - 0.077 13.1 0.4 0.11 12.6 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Polysacc_deac_1 PF01522.16 OAJ08600.1 - 5.1e-17 61.6 0.0 8.3e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Macoilin PF09726.4 OAJ08601.1 - 5.5 5.1 19.4 7.2 4.7 13.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DEAD PF00270.24 OAJ08605.1 - 4.5e-40 136.9 0.0 8.3e-40 136.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ08605.1 - 4.6e-20 71.2 0.1 1e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ08605.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HRXXH PF13933.1 OAJ08606.1 - 3.6e-80 268.9 0.0 4e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family HCV_NS5a_1a PF08300.8 OAJ08606.1 - 0.061 13.2 0.3 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a zinc finger domain MVL PF12151.3 OAJ08606.1 - 0.17 11.5 2.6 0.35 10.5 1.8 1.5 1 0 0 1 1 1 0 Mannan-binding protein Methyltransf_15 PF09445.5 OAJ08608.1 - 1.5e-33 115.6 0.0 2.6e-27 95.3 0.0 2.4 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 OAJ08608.1 - 6.2e-10 39.1 0.0 1.4e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ08608.1 - 2.6e-07 31.1 0.0 6.8e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 OAJ08608.1 - 4.1e-07 29.7 0.0 6.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 OAJ08608.1 - 2.5e-05 23.9 0.0 5.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 OAJ08608.1 - 0.00011 21.7 0.0 0.00011 21.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 OAJ08608.1 - 0.00025 20.1 0.0 0.00042 19.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 OAJ08608.1 - 0.00066 20.0 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 OAJ08608.1 - 0.0049 16.0 1.3 0.016 14.3 0.9 1.7 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.6 OAJ08608.1 - 0.033 12.8 0.0 0.033 12.8 0.0 1.5 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase Cons_hypoth95 PF03602.10 OAJ08608.1 - 0.071 12.5 0.1 0.071 12.5 0.1 2.8 3 0 0 3 3 3 0 Conserved hypothetical protein 95 TRM PF02005.11 OAJ08608.1 - 0.16 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase SAPS PF04499.10 OAJ08608.1 - 0.22 10.1 5.2 0.19 10.3 2.3 1.7 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF1326 PF07040.6 OAJ08608.1 - 0.3 10.8 0.1 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1326) Suf PF05843.9 OAJ08608.1 - 7 6.2 19.3 0.39 10.3 9.4 1.8 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Transposase_21 PF02992.9 OAJ08614.1 - 3.1e-24 85.3 0.0 5.4e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Herpes_capsid PF06112.6 OAJ08614.1 - 3.3 7.7 10.5 6.9 6.6 7.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein IncA PF04156.9 OAJ08615.1 - 0.54 9.8 4.3 1.2 8.7 0.9 2.1 2 0 0 2 2 2 0 IncA protein DUF1253 PF06862.7 OAJ08619.1 - 7.2e-94 314.6 0.0 1.1e-93 314.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1253) TFIIA PF03153.8 OAJ08619.1 - 0.023 14.5 4.7 0.038 13.9 3.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AICARFT_IMPCHas PF01808.13 OAJ08620.1 - 1.5e-104 349.4 0.2 1.9e-104 349.1 0.1 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 OAJ08620.1 - 1.3e-21 76.2 0.0 2.4e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain MFS_1 PF07690.11 OAJ08623.1 - 1.8e-14 53.2 53.7 6.1e-14 51.4 30.3 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily A_deamin PF02137.13 OAJ08636.1 - 9.9e-32 110.5 0.0 1.5e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Adeno_E4_ORF3 PF06931.6 OAJ08637.1 - 0.17 11.9 1.4 0.19 11.8 1.0 1.3 1 1 0 1 1 1 0 Mastadenovirus E4 ORF3 protein DUF2628 PF10947.3 OAJ08637.1 - 2.6 7.8 12.1 3.7 7.3 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) FA_desaturase PF00487.19 OAJ08637.1 - 2.9 7.2 7.7 3.2 7.1 5.3 1.2 1 0 0 1 1 1 0 Fatty acid desaturase ABC2_membrane_2 PF12679.2 OAJ08637.1 - 3.6 6.3 11.5 4 6.2 8.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein RVT_2 PF07727.9 OAJ08646.1 - 3.9e-84 281.4 0.0 5.3e-84 281.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08646.1 - 4e-20 72.1 0.0 2.2e-19 69.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ08646.1 - 6.3e-07 28.9 0.0 1.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC_2 PF13696.1 OAJ08647.1 - 0.096 12.1 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 OAJ08647.1 - 1.2 9.1 3.6 2.2 8.3 2.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Amidase PF01425.16 OAJ08653.1 - 2.4e-89 300.2 0.0 7.8e-89 298.5 0.0 1.8 2 0 0 2 2 2 1 Amidase DUF455 PF04305.9 OAJ08654.1 - 5e-93 311.0 0.0 6.6e-93 310.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 OAJ08654.1 - 3.5e-08 32.8 1.5 1.3e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 OAJ08654.1 - 0.0012 18.5 0.0 0.0033 17.1 0.0 1.7 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain Histone PF00125.19 OAJ08659.1 - 1.2e-28 99.0 0.4 1.2e-28 99.0 0.3 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ08659.1 - 7.5e-06 26.0 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 OAJ08659.1 - 0.0058 15.9 0.2 0.0058 15.9 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 OAJ08659.1 - 0.024 14.6 1.5 0.1 12.6 0.1 2.1 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Tfb2 PF03849.9 OAJ08660.1 - 1e-15 57.2 0.0 1.2e-15 57.0 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 OrfB_Zn_ribbon PF07282.6 OAJ08666.1 - 0.00061 19.3 1.1 0.021 14.4 0.8 2.5 1 1 0 1 1 1 1 Putative transposase DNA-binding domain RVT_1 PF00078.22 OAJ08674.1 - 0.0066 15.8 0.0 0.015 14.6 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.17 OAJ08675.1 - 0.0032 17.1 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 OAJ08679.1 - 6.8e-15 55.0 0.0 1.6e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 OAJ08679.1 - 0.0052 16.6 4.7 0.0052 16.6 3.2 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ08679.1 - 4.8 6.9 6.9 0.86 9.3 1.8 2.1 2 0 0 2 2 2 0 Zinc knuckle rve PF00665.21 OAJ08680.1 - 1.3e-18 67.2 0.0 2e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ08680.1 - 0.0012 18.3 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Pkinase PF00069.20 OAJ08684.1 - 1.8e-69 233.8 0.0 2.2e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ08684.1 - 3.1e-29 101.8 0.0 3.7e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ08684.1 - 3.7e-06 26.1 0.0 4.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ08684.1 - 0.0091 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 OAJ08684.1 - 0.024 13.9 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 OAJ08684.1 - 0.035 13.8 0.1 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF677 PF05055.7 OAJ08688.1 - 0.061 11.9 0.1 0.065 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Glyco_transf_20 PF00982.16 OAJ08689.1 - 2.8e-54 184.3 0.0 1.2e-46 159.1 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Serglycin PF04360.7 OAJ08689.1 - 0.35 10.6 11.1 0.081 12.6 3.8 2.3 2 0 0 2 2 2 0 Serglycin RVT_2 PF07727.9 OAJ08694.1 - 1e-89 299.7 0.0 1.5e-89 299.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08694.1 - 1.7e-26 92.6 0.1 6.5e-26 90.8 0.1 2.1 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ08694.1 - 8.3e-06 25.3 0.0 2.6e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ08694.1 - 0.00088 18.7 0.0 0.0023 17.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 OAJ08695.1 - 6.3e-05 22.7 2.6 0.00011 21.9 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 OAJ08695.1 - 0.00022 20.6 4.1 0.0011 18.3 2.5 2.3 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 OAJ08695.1 - 0.00026 20.6 1.8 0.00069 19.3 1.3 1.7 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 OAJ08695.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type TIP_N PF12457.3 OAJ08695.1 - 0.54 10.3 5.2 1.1 9.3 3.6 1.5 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal TP_methylase PF00590.15 OAJ08710.1 - 6.9e-33 114.1 0.2 1.3e-32 113.2 0.1 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 OAJ08710.1 - 1.9e-07 31.3 0.0 0.00036 20.7 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 OAJ08710.1 - 5e-07 28.5 0.1 1e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.1 OAJ08710.1 - 3.1e-06 26.3 0.0 0.0034 16.6 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal gag-asp_proteas PF13975.1 OAJ08716.1 - 0.0025 17.5 0.0 0.0091 15.7 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.1 OAJ08716.1 - 0.0051 16.2 0.1 0.009 15.4 0.1 1.3 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 OAJ08716.1 - 0.0056 17.1 0.0 0.6 10.6 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.18 OAJ08716.1 - 0.065 13.2 1.4 0.1 12.5 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle GCV_T_C PF08669.6 OAJ08716.1 - 0.081 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain ZZ PF00569.12 OAJ08716.1 - 0.089 12.3 2.2 0.17 11.4 1.5 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type RVT_2 PF07727.9 OAJ08718.1 - 2.4e-86 288.7 0.0 3.2e-86 288.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 OAJ08719.1 - 9e-07 28.5 3.0 2.1e-06 27.3 2.1 1.7 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 OAJ08719.1 - 3.6e-05 23.5 0.0 7.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 OAJ08719.1 - 0.31 10.7 0.9 0.63 9.7 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Prenylcys_lyase PF07156.9 OAJ08725.1 - 7.6e-39 133.6 0.0 7e-20 71.2 0.0 2.8 2 1 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 OAJ08725.1 - 3.8e-10 39.6 0.2 2.7e-09 36.9 0.1 2.4 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAJ08725.1 - 7.2e-07 29.2 0.1 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ08725.1 - 1.6e-05 23.9 0.2 4e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAJ08725.1 - 5.9e-05 22.8 0.2 0.0032 17.2 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 OAJ08725.1 - 0.011 14.6 0.6 0.011 14.6 0.4 1.7 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 OAJ08725.1 - 0.012 14.2 0.1 0.018 13.6 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 OAJ08725.1 - 0.012 15.6 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ08725.1 - 0.018 14.1 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 OAJ08725.1 - 0.021 13.8 1.5 0.032 13.3 1.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 OAJ08725.1 - 0.035 12.5 0.1 0.05 12.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 OAJ08725.1 - 0.06 13.0 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 OAJ08725.1 - 0.11 12.9 0.1 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAJ08725.1 - 0.21 10.4 3.5 0.41 9.4 0.9 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A TAFII28 PF04719.9 OAJ08725.1 - 0.24 11.2 0.0 0.44 10.3 0.0 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Lactonase PF10282.4 OAJ08726.1 - 8e-18 64.6 0.0 2.5e-17 62.9 0.0 1.7 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Eno-Rase_NADH_b PF12242.3 OAJ08726.1 - 0.066 13.0 0.0 0.68 9.7 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HMG_box PF00505.14 OAJ08729.1 - 4e-08 33.3 0.8 9.3e-08 32.2 0.9 3.5 3 1 0 3 3 3 2 HMG (high mobility group) box Exo_endo_phos_2 PF14529.1 OAJ08734.1 - 9.1e-12 44.6 0.0 1.9e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ08734.1 - 4.1e-08 33.4 0.0 8.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SRP54 PF00448.17 OAJ08734.1 - 0.027 13.8 0.0 0.062 12.7 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain zf-CCHC_4 PF14392.1 OAJ08735.1 - 3.7 7.2 10.1 1.6 8.4 1.0 2.5 2 0 0 2 2 2 0 Zinc knuckle ICL PF00463.16 OAJ08742.1 - 1.8e-05 23.1 0.1 1.9e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Phage_integrase PF00589.17 OAJ08743.1 - 2.4e-05 24.0 0.0 3.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family DUF1308 PF07000.6 OAJ08746.1 - 2.8e-20 72.3 0.0 2.8e-10 39.4 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1308) Pkinase PF00069.20 OAJ08747.1 - 6.8e-06 25.4 0.0 1.2e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ08747.1 - 0.076 12.0 0.0 0.28 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase DUF866 PF05907.8 OAJ08755.1 - 4e-38 130.4 0.3 5.1e-38 130.0 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF1272 PF06906.6 OAJ08755.1 - 0.012 15.4 2.1 0.06 13.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Cytochrome_C7 PF14522.1 OAJ08755.1 - 0.061 12.9 1.2 0.13 11.8 0.8 1.5 1 0 0 1 1 1 0 Cytochrome c7 Lar_restr_allev PF14354.1 OAJ08755.1 - 0.69 10.2 7.2 1.7 9.0 0.3 2.7 1 1 1 2 2 2 0 Restriction alleviation protein Lar DDE_3 PF13358.1 OAJ08759.1 - 1.4e-09 37.8 0.1 2.1e-09 37.2 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease PqqD PF05402.7 OAJ08759.1 - 0.14 12.1 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Abhydrolase_6 PF12697.2 OAJ08764.1 - 5e-14 52.7 0.6 6.9e-14 52.2 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ08764.1 - 3.8e-06 26.6 0.1 6.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ08764.1 - 2.7e-05 23.9 0.1 5.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_S27 PF01599.14 OAJ08771.1 - 0.09 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S27a GSK-3_bind PF05350.7 OAJ08772.1 - 0.093 12.1 1.7 0.14 11.5 1.2 1.3 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Asp_protease_2 PF13650.1 OAJ08773.1 - 5.3e-05 23.6 0.0 0.00014 22.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ08773.1 - 0.003 17.4 0.0 0.0082 16.0 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ08773.1 - 0.018 14.8 0.3 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Zn_protease PF05618.6 OAJ08773.1 - 0.053 13.1 0.9 2.8 7.6 0.0 2.8 3 0 0 3 3 3 0 Putative ATP-dependant zinc protease RVT_1 PF00078.22 OAJ08774.1 - 7.1e-18 64.7 0.0 1.4e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exc PF07825.6 OAJ08774.1 - 0.29 10.9 2.8 0.32 10.7 0.4 2.1 2 0 0 2 2 2 0 Excisionase-like protein G-patch PF01585.18 OAJ08777.1 - 2.9e-11 42.9 5.6 4.2e-11 42.4 0.9 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 OAJ08777.1 - 0.00012 21.8 1.2 0.00019 21.2 0.8 1.5 1 1 0 1 1 1 1 DExH-box splicing factor binding site DAP3 PF10236.4 OAJ08778.1 - 1.9e-38 132.1 0.0 4.4e-38 130.9 0.0 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 OAJ08778.1 - 0.00077 19.4 4.2 0.0018 18.3 2.9 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ08778.1 - 0.018 15.1 0.0 1 9.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAJ08778.1 - 0.022 14.5 0.1 0.079 12.7 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain GTP1_OBG PF01018.17 OAJ08779.1 - 1.6e-38 131.8 2.2 7.5e-28 97.1 0.4 3.1 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.18 OAJ08779.1 - 2.8e-17 62.7 0.0 7.5e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ08779.1 - 0.00041 19.6 0.1 0.00081 18.6 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 OAJ08779.1 - 0.017 14.5 0.0 3.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ArgK PF03308.11 OAJ08779.1 - 0.12 11.1 0.7 0.81 8.4 0.1 2.2 2 0 0 2 2 2 0 ArgK protein ABC_tran PF00005.22 OAJ08779.1 - 0.15 12.3 0.8 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.18 OAJ08779.1 - 0.47 10.2 3.8 0.52 10.1 0.1 2.7 2 1 0 2 2 2 0 Dynamin family CPSase_L_chain PF00289.17 OAJ08782.1 - 1.5e-16 60.4 0.0 3.1e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 OAJ08782.1 - 0.00043 20.0 0.0 0.00069 19.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 OAJ08782.1 - 0.00045 19.5 0.0 0.00068 18.9 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 OAJ08782.1 - 0.083 11.6 0.0 0.29 9.8 0.0 1.7 1 1 1 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_chain PF00289.17 OAJ08783.1 - 0.00065 19.7 0.0 0.00098 19.2 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Integrase_DNA PF02920.10 OAJ08784.1 - 0.12 11.8 0.8 0.25 10.7 0.1 1.9 2 0 0 2 2 2 0 DNA binding domain of tn916 integrase YuzL PF14115.1 OAJ08784.1 - 0.48 10.7 3.0 0.84 9.9 2.1 1.4 1 0 0 1 1 1 0 YuzL-like protein CPSase_L_D2 PF02786.12 OAJ08785.1 - 5.3e-64 215.3 0.0 5.9e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 OAJ08785.1 - 1.1e-15 57.8 0.0 1.2e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 OAJ08785.1 - 3.4e-08 33.0 0.0 4.1e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAJ08785.1 - 2.7e-06 26.3 0.0 0.036 12.8 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 OAJ08785.1 - 2.6e-05 24.1 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 OAJ08785.1 - 7.4e-05 22.2 0.0 0.00022 20.7 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.1 OAJ08785.1 - 0.0055 15.9 0.1 0.0089 15.2 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain MGS PF02142.17 OAJ08786.1 - 0.0095 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Epimerase PF01370.16 OAJ08786.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HsbA PF12296.3 OAJ08789.1 - 7.6e-16 58.0 8.9 1e-15 57.6 6.2 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Reo_sigmaC PF04582.7 OAJ08789.1 - 0.22 10.6 3.1 0.25 10.4 1.7 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 OAJ08789.1 - 1.6 8.5 9.3 1.4 8.7 5.4 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HsbA PF12296.3 OAJ08790.1 - 4e-15 55.7 11.6 4.7e-15 55.5 8.1 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Reo_sigmaC PF04582.7 OAJ08790.1 - 0.027 13.6 3.7 0.034 13.3 2.5 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DivIVA PF05103.8 OAJ08790.1 - 0.062 13.3 1.0 0.085 12.9 0.7 1.2 1 0 0 1 1 1 0 DivIVA protein DUF3713 PF12506.3 OAJ08790.1 - 0.073 13.1 2.8 0.12 12.5 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) DUF759 PF05537.6 OAJ08790.1 - 0.074 11.8 0.9 0.09 11.5 0.6 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) Pox_A6 PF04924.7 OAJ08790.1 - 0.11 11.2 1.6 0.13 11.0 1.1 1.1 1 0 0 1 1 1 0 Poxvirus A6 protein DUF1341 PF07071.6 OAJ08790.1 - 0.13 11.7 3.4 0.16 11.4 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1341) Cupin_8 PF13621.1 OAJ08791.1 - 6.9e-25 87.9 0.0 1.8e-24 86.6 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 OAJ08791.1 - 3.3e-08 33.1 0.1 3.3e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 OAJ08791.1 - 1e-05 25.7 0.0 0.00082 19.6 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 OAJ08791.1 - 0.034 13.6 0.0 0.14 11.7 0.0 2.0 1 0 0 1 1 1 0 Cupin domain Snf7 PF03357.16 OAJ08794.1 - 1.4e-38 131.9 15.6 2.1e-38 131.3 10.8 1.2 1 0 0 1 1 1 1 Snf7 TPR_MLP1_2 PF07926.7 OAJ08794.1 - 0.001 18.7 6.1 0.0015 18.2 4.2 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.7 OAJ08794.1 - 0.049 12.9 16.7 0.11 11.8 3.9 2.1 1 1 1 2 2 2 0 PspA/IM30 family YlqD PF11068.3 OAJ08794.1 - 0.4 10.7 12.7 3.1 7.8 8.8 2.1 1 1 0 1 1 1 0 YlqD protein ADK PF00406.17 OAJ08795.1 - 2.1e-44 151.0 0.0 9.8e-24 83.9 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase AAA_18 PF13238.1 OAJ08795.1 - 1.1e-11 45.1 0.0 2.1e-11 44.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 OAJ08795.1 - 1.3e-07 31.1 0.2 0.0021 17.4 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_17 PF13207.1 OAJ08795.1 - 1.1e-06 29.4 0.0 1.8e-06 28.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ08795.1 - 5e-05 23.2 0.0 0.00062 19.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ08795.1 - 0.048 13.4 0.1 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain zf-CHCC PF10276.4 OAJ08796.1 - 9.9e-18 63.7 1.1 1.5e-17 63.1 0.8 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 OAJ08796.1 - 0.002 17.8 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb DUF605 PF04652.11 OAJ08796.1 - 0.0057 16.1 6.9 0.0063 15.9 4.8 1.0 1 0 0 1 1 1 1 Vta1 like RVT_1 PF00078.22 OAJ08804.1 - 1.9e-17 63.3 0.0 3.7e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08804.1 - 3.7e-13 49.6 0.0 6.9e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ08804.1 - 1e-05 25.9 0.0 2.8e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ08804.1 - 0.0017 18.2 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ08804.1 - 0.0052 16.5 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease HpaP PF09483.5 OAJ08805.1 - 0.23 11.4 8.6 0.27 11.1 6.0 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Herpes_capsid PF06112.6 OAJ08805.1 - 0.91 9.5 7.8 1.1 9.2 5.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Stm1_N PF09598.5 OAJ08805.1 - 2.8 8.7 14.4 4.6 8.0 9.4 1.8 1 1 1 2 2 2 0 Stm1 Pheromone PF08015.6 OAJ08805.1 - 5.2 7.9 7.2 89 4.0 5.0 2.2 1 1 0 1 1 1 0 Fungal mating-type pheromone Med3 PF11593.3 OAJ08805.1 - 7.3 5.7 8.5 7.6 5.6 5.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-U1 PF06220.7 OAJ08816.1 - 8.2e-16 57.2 3.4 1.2e-15 56.8 2.4 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 OAJ08816.1 - 0.15 12.2 0.9 0.31 11.2 0.6 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAJ08816.1 - 1.4 9.2 3.9 24 5.3 2.7 2.6 1 1 0 1 1 1 0 Zinc-finger of C2H2 type TIP41 PF04176.8 OAJ08817.1 - 1.3e-43 148.3 0.0 1.4e-39 135.2 0.0 2.7 2 1 0 2 2 2 2 TIP41-like family RecQ5 PF06959.6 OAJ08822.1 - 0.05 13.2 0.6 0.2 11.2 0.0 2.3 2 0 0 2 2 2 0 RecQ helicase protein-like 5 (RecQ5) IQ PF00612.22 OAJ08822.1 - 0.55 10.0 5.5 0.17 11.5 0.3 3.0 3 0 0 3 3 3 0 IQ calmodulin-binding motif DEAD PF00270.24 OAJ08823.1 - 3.7e-09 36.2 0.0 5.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 OAJ08823.1 - 0.12 11.6 0.0 0.37 9.9 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein PMM PF03332.8 OAJ08827.1 - 2.9e-101 337.6 0.4 3.5e-101 337.3 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 OAJ08827.1 - 4.6e-05 23.1 0.0 0.00026 20.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF600 PF04634.7 OAJ08827.1 - 0.072 13.1 0.1 0.19 11.7 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF600 Response_reg PF00072.19 OAJ08828.1 - 7.4e-20 71.0 0.0 2.1e-19 69.5 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 OAJ08828.1 - 2.6e-17 62.5 0.2 5.6e-17 61.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 OAJ08828.1 - 7.4e-08 32.2 0.2 5.2e-07 29.5 0.1 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Fmp27 PF10344.4 OAJ08833.1 - 0.04 11.5 1.2 0.076 10.6 0.8 1.3 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Velvet PF11754.3 OAJ08835.1 - 2.9e-43 147.8 0.0 2.3e-36 125.3 0.0 2.1 2 0 0 2 2 2 2 Velvet factor WD40 PF00400.27 OAJ08836.1 - 1.5e-22 78.5 7.0 2.5e-11 42.9 0.1 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat RXT2_N PF08595.6 OAJ08836.1 - 1.1 9.0 2.8 1.6 8.5 1.9 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 OAJ08836.1 - 8.2 5.9 7.0 11 5.5 4.8 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Mito_carr PF00153.22 OAJ08841.1 - 0.027 14.1 0.5 2.2 8.0 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial carrier protein Peptidase_C1_2 PF03051.10 OAJ08842.1 - 2.3e-32 112.1 0.0 1.1e-29 103.2 0.0 2.0 2 0 0 2 2 2 2 Peptidase C1-like family BTV_NS2 PF04514.7 OAJ08845.1 - 0.22 10.3 1.0 1.4 7.7 0.4 1.9 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Synaptobrevin PF00957.16 OAJ08845.1 - 1.3 8.6 3.2 6.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Synaptobrevin CDC45 PF02724.9 OAJ08846.1 - 0.037 12.0 9.5 0.068 11.1 6.6 1.4 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 OAJ08846.1 - 0.25 9.2 10.7 0.35 8.7 7.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1640 PF07798.6 OAJ08850.1 - 5.8e-13 49.2 0.3 8.5e-13 48.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) SF-assemblin PF06705.6 OAJ08850.1 - 0.0035 16.5 2.0 0.0055 15.8 1.4 1.3 1 0 0 1 1 1 1 SF-assemblin/beta giardin OmpH PF03938.9 OAJ08850.1 - 0.0078 16.1 1.2 0.0078 16.1 0.8 2.1 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) F-box PF00646.28 OAJ08851.1 - 2.8e-06 26.8 0.0 7.3e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 F-box domain DUF4530 PF15039.1 OAJ08851.1 - 0.035 13.9 0.1 0.16 11.8 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4530) F-box-like PF12937.2 OAJ08851.1 - 0.041 13.6 0.0 0.099 12.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box-like_2 PF13013.1 OAJ08851.1 - 0.045 13.4 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain F-box PF00646.28 OAJ08852.1 - 0.00028 20.4 0.0 0.00056 19.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ08852.1 - 0.00042 19.9 0.1 0.00089 18.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 OAJ08852.1 - 0.0049 16.5 0.0 0.0093 15.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain P53_TAD PF08563.6 OAJ08852.1 - 2 7.5 4.7 10 5.3 0.8 2.5 2 0 0 2 2 2 0 P53 transactivation motif APH PF01636.18 OAJ08856.1 - 1.6e-17 64.0 0.0 2.9e-17 63.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family CDC37_M PF08565.6 OAJ08856.1 - 0.16 11.4 0.1 0.24 10.8 0.1 1.2 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain NAD_binding_7 PF13241.1 OAJ08862.1 - 1.1e-27 96.2 0.0 2e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 OAJ08862.1 - 1.9e-21 75.1 0.2 3.2e-21 74.4 0.2 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 OAJ08862.1 - 3.6e-10 38.6 0.1 6.5e-10 37.8 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central SH3_9 PF14604.1 OAJ08863.1 - 6.6e-14 51.2 0.2 1.6e-13 50.0 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ08863.1 - 1.7e-13 49.7 0.1 3.5e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ08863.1 - 2.7e-12 45.9 0.1 7e-12 44.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 OAJ08863.1 - 0.00039 20.2 3.5 0.063 13.1 0.2 2.5 2 0 0 2 2 2 2 WW domain PQQ PF01011.16 OAJ08863.1 - 0.0077 15.7 0.0 0.035 13.6 0.0 2.1 2 0 0 2 2 2 1 PQQ enzyme repeat DUF617 PF04759.8 OAJ08863.1 - 0.022 14.4 0.3 0.09 12.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF617 COesterase PF00135.23 OAJ08866.1 - 3.8e-109 365.8 0.1 5.2e-109 365.3 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ08866.1 - 8.3e-06 25.5 0.1 9.7e-05 22.0 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Mtc PF03820.12 OAJ08867.1 - 1.3e-85 286.8 0.0 1.5e-85 286.5 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier PSK_trans_fac PF07704.6 OAJ08872.1 - 0.17 12.5 1.6 0.24 12.1 1.1 1.3 1 1 0 1 1 1 0 Rv0623-like transcription factor PilZ PF07238.9 OAJ08873.1 - 0.059 13.3 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 PilZ domain Acyltransferase PF01553.16 OAJ08881.1 - 3.4e-20 71.8 0.0 7.5e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase DUF1675 PF07897.6 OAJ08881.1 - 0.041 13.7 0.8 0.067 13.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) ELL PF10390.4 OAJ08881.1 - 0.054 12.7 4.1 0.084 12.0 2.8 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL DUF3275 PF11679.3 OAJ08881.1 - 0.089 12.4 3.4 0.19 11.3 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) MFS_1 PF07690.11 OAJ08885.1 - 6.7e-39 133.5 40.8 6.7e-39 133.5 28.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAJ08885.1 - 7.3e-13 47.5 16.3 9.3e-13 47.2 11.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sporozoite_P67 PF05642.6 OAJ08886.1 - 0.035 12.0 1.4 0.04 11.8 1.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GATA PF00320.22 OAJ08889.1 - 4.4e-17 61.1 4.6 1e-16 59.9 3.2 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 OAJ08889.1 - 9.5e-14 50.6 2.0 1.7e-13 49.8 1.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) FA_hydroxylase PF04116.8 OAJ08893.1 - 3.1e-06 27.5 9.7 4e-06 27.2 6.7 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Ribonuclease_T2 PF00445.13 OAJ08894.1 - 2.9e-31 108.5 0.0 3.7e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Melibiase PF02065.13 OAJ08894.1 - 0.067 11.8 0.0 0.78 8.3 0.0 2.0 2 0 0 2 2 2 0 Melibiase AIRS PF00586.19 OAJ08894.1 - 0.09 13.0 0.0 0.27 11.4 0.0 1.8 1 1 0 1 1 1 0 AIR synthase related protein, N-terminal domain DUF3292 PF11696.3 OAJ08898.1 - 3e-161 537.5 0.0 3.7e-73 246.4 0.0 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF3292) PBP1_TM PF14812.1 OAJ08898.1 - 7.3 6.9 19.5 6.5 7.1 4.5 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2722 PF10846.3 OAJ08899.1 - 0.012 14.6 0.7 0.012 14.6 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) GHMP_kinases_C PF08544.8 OAJ08899.1 - 2.4 8.4 7.0 3.5 7.8 0.0 2.7 2 1 1 3 3 3 0 GHMP kinases C terminal AMP-binding PF00501.23 OAJ08903.1 - 2.7e-66 223.6 0.2 3.5e-66 223.3 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ08903.1 - 1.4e-21 77.2 1.7 8.2e-21 74.7 0.1 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain EamA PF00892.15 OAJ08904.1 - 6.6e-07 29.4 20.9 0.00082 19.4 0.4 2.8 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 OAJ08904.1 - 0.00092 19.3 0.5 0.00092 19.3 0.3 2.7 3 0 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 OAJ08904.1 - 0.021 14.4 18.3 0.096 12.3 7.3 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family UAA PF08449.6 OAJ08904.1 - 0.035 13.0 3.0 0.078 11.8 0.1 2.1 2 0 0 2 2 2 0 UAA transporter family MDM31_MDM32 PF08118.6 OAJ08909.1 - 1.8e-121 406.0 2.0 4.1e-56 190.4 0.0 3.1 2 1 0 3 3 3 3 Yeast mitochondrial distribution and morphology (MDM) proteins NOC3p PF07540.6 OAJ08915.1 - 9.4e-22 77.1 0.3 9.3e-18 64.3 0.0 3.0 3 0 0 3 3 3 2 Nucleolar complex-associated protein CBF PF03914.12 OAJ08915.1 - 1.1e-17 63.9 0.0 1.1e-17 63.9 0.0 4.4 4 2 1 5 5 5 1 CBF/Mak21 family 60KD_IMP PF02096.15 OAJ08915.1 - 0.55 9.8 0.5 0.96 9.0 0.4 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein PHD PF00628.24 OAJ08918.1 - 2.7e-05 23.7 8.2 2.7e-05 23.7 5.7 2.6 2 1 0 2 2 2 1 PHD-finger C1_1 PF00130.17 OAJ08918.1 - 0.0086 15.7 0.3 0.0086 15.7 0.2 2.9 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FANCL_C PF11793.3 OAJ08918.1 - 0.049 13.5 1.1 0.15 12.0 0.8 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain PHD_2 PF13831.1 OAJ08918.1 - 1.4 8.3 8.3 0.5 9.7 0.4 3.5 3 0 0 3 3 3 0 PHD-finger zf-HC5HC2H PF13771.1 OAJ08918.1 - 1.9 8.6 8.9 0.37 10.9 2.2 2.7 2 1 0 2 2 2 0 PHD-like zinc-binding domain ABC_membrane PF00664.18 OAJ08922.1 - 8.2e-07 28.7 0.0 8.9e-07 28.5 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region SBDS PF01172.13 OAJ08923.1 - 2.9e-16 59.0 0.4 3.6e-16 58.7 0.2 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Methyltransf_18 PF12847.2 OAJ08924.1 - 8.7e-09 35.9 0.0 1.7e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ08924.1 - 1.5e-05 24.8 0.0 3.6e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ08924.1 - 0.00025 20.6 0.2 0.00049 19.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 OAJ08924.1 - 0.0032 17.0 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 OAJ08924.1 - 0.05 14.0 0.0 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 OAJ08924.1 - 0.082 12.2 0.2 0.26 10.6 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_26 PF13659.1 OAJ08924.1 - 0.092 12.7 0.0 0.17 11.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 OAJ08924.1 - 0.18 10.4 0.0 0.32 9.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) ABA_GPCR PF12430.3 OAJ08925.1 - 3.8e-34 117.5 4.0 8.3e-34 116.4 2.8 1.5 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 OAJ08925.1 - 1.4e-12 47.4 0.8 3.4e-12 46.2 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) LcrR PF09621.5 OAJ08925.1 - 0.044 13.0 0.4 0.1 11.8 0.1 1.7 2 0 0 2 2 2 0 Type III secretion system regulator (LcrR) rve PF00665.21 OAJ08928.1 - 4.8e-16 58.9 0.0 1.7e-15 57.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ08928.1 - 5.9e-06 25.7 0.1 0.001 18.4 0.0 2.6 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ08928.1 - 0.00065 20.1 1.0 0.0019 18.6 0.1 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ08928.1 - 0.012 15.3 0.2 0.036 13.8 0.1 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ08928.1 - 0.073 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease SOG2 PF10428.4 OAJ08930.1 - 0.29 9.7 6.4 0.33 9.5 4.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Rrn6 PF10214.4 OAJ08930.1 - 0.77 7.7 2.4 0.95 7.4 1.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Herpes_capsid PF06112.6 OAJ08930.1 - 0.94 9.5 11.6 1.3 9.0 8.0 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein MSA-2c PF12238.3 OAJ08930.1 - 1.5 8.4 9.1 2 8.0 6.3 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Kisspeptin PF15152.1 OAJ08930.1 - 5.2 7.8 7.0 1.7 9.4 0.4 2.2 1 1 1 2 2 2 0 Kisspeptin Pyr_redox_2 PF07992.9 OAJ08937.1 - 1.3e-26 93.7 0.0 1.6e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ08937.1 - 5.5e-12 45.9 3.4 1.3e-09 38.3 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAJ08937.1 - 2.5e-06 27.7 0.2 6.1e-06 26.4 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAJ08937.1 - 4.5e-05 22.7 0.5 6e-05 22.2 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 OAJ08937.1 - 0.0016 17.4 0.0 0.0095 14.8 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 OAJ08937.1 - 0.0037 16.3 0.1 0.0061 15.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 OAJ08937.1 - 0.0038 17.2 0.8 0.011 15.7 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAJ08937.1 - 0.0043 15.9 0.7 0.037 12.8 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 OAJ08937.1 - 0.014 13.8 1.3 1.2 7.4 0.6 2.1 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.13 OAJ08937.1 - 0.16 11.6 1.3 3.7 7.1 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glutenin_hmw PF03157.8 OAJ08938.1 - 0.44 8.7 16.1 0.63 8.2 11.1 1.1 1 0 0 1 1 1 0 High molecular weight glutenin subunit WD40 PF00400.27 OAJ08942.1 - 1.9e-16 59.2 0.3 9e-10 38.0 0.0 2.0 2 0 0 2 2 2 2 WD domain, G-beta repeat E3_UbLigase_EDD PF11547.3 OAJ08942.1 - 0.15 11.5 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD RVT_1 PF00078.22 OAJ08945.1 - 9.6e-19 67.5 0.0 2.4e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08945.1 - 4.7e-13 49.3 0.0 1.4e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Phage_integrase PF00589.17 OAJ08951.1 - 9.2e-05 22.1 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF4431 PF14485.1 OAJ08951.1 - 0.09 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) RVT_3 PF13456.1 OAJ08952.1 - 0.0021 17.8 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like DNA_pol_viral_C PF00336.13 OAJ08952.1 - 0.054 12.7 0.3 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain HNH_2 PF13391.1 OAJ08956.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.4 1 1 0 1 1 1 0 HNH endonuclease Daxx PF03344.10 OAJ08957.1 - 0.0043 15.6 13.2 0.0044 15.5 9.2 1.1 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 OAJ08957.1 - 0.011 13.7 17.0 0.012 13.6 11.8 1.0 1 0 0 1 1 1 0 Nop14-like family Tom22 PF04281.8 OAJ08957.1 - 0.07 12.6 6.7 0.098 12.1 4.7 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Pox_Ag35 PF03286.9 OAJ08957.1 - 0.073 12.5 6.8 0.093 12.2 4.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFIIF_alpha PF05793.7 OAJ08957.1 - 0.15 10.4 13.4 0.16 10.3 9.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-T PF15511.1 OAJ08957.1 - 0.19 10.9 14.3 0.22 10.7 9.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1510 PF07423.6 OAJ08957.1 - 0.21 10.9 11.5 0.23 10.7 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NOA36 PF06524.7 OAJ08957.1 - 0.59 9.3 13.6 0.7 9.0 9.4 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 OAJ08957.1 - 0.66 7.9 14.7 0.73 7.8 10.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Upf2 PF04050.9 OAJ08957.1 - 0.66 9.7 15.8 0.84 9.3 11.0 1.3 1 0 0 1 1 1 0 Up-frameshift suppressor 2 BUD22 PF09073.5 OAJ08957.1 - 0.95 8.4 20.1 1.1 8.2 13.9 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.7 OAJ08957.1 - 1 8.5 17.7 1.2 8.3 12.3 1.1 1 0 0 1 1 1 0 SDA1 DUF2201_N PF13203.1 OAJ08957.1 - 1.2 8.2 7.4 1.3 8.1 5.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2890 PF11081.3 OAJ08957.1 - 1.4 8.9 10.4 1.7 8.6 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Vfa1 PF08432.5 OAJ08957.1 - 1.4 8.8 8.3 1.7 8.6 5.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.7 OAJ08957.1 - 3.3 7.5 7.1 3.8 7.3 4.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 OAJ08957.1 - 3.7 5.1 4.4 3.9 5.0 3.0 1.0 1 0 0 1 1 1 0 Ycf1 Pox_RNA_Pol_19 PF05320.7 OAJ08957.1 - 3.9 7.2 8.6 5.9 6.6 6.0 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF4637 PF15470.1 OAJ08957.1 - 8.9 5.9 12.4 11 5.5 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) PIN_4 PF13638.1 OAJ08958.1 - 0.013 15.5 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 PIN domain rve PF00665.21 OAJ08962.1 - 9.6e-16 57.9 0.0 2.4e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ08962.1 - 2.1e-09 37.0 0.1 4.5e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3546 PF12066.3 OAJ08968.1 - 1.3e-14 54.1 0.3 3.9e-14 52.5 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 OAJ08968.1 - 0.00042 20.5 0.0 0.0015 18.7 0.0 2.0 1 0 0 1 1 1 1 Arsenite-resistance protein 2 GRP PF07172.6 OAJ08971.1 - 4.4 7.8 19.2 9.4 6.7 13.3 1.5 1 0 0 1 1 1 0 Glycine rich protein family RRM_6 PF14259.1 OAJ08974.1 - 2.4e-10 40.2 0.0 4.5e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ08974.1 - 7.3e-10 38.3 0.0 8e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ08974.1 - 1.9e-05 24.4 0.0 3.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4283 PF14111.1 OAJ08974.1 - 0.067 12.2 0.0 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4283) Sec5 PF15469.1 OAJ08975.1 - 2.9e-55 186.8 1.6 3.9e-54 183.1 0.0 3.0 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.6 OAJ08975.1 - 0.0098 15.7 0.0 0.062 13.1 0.0 2.5 1 0 0 1 1 1 1 Vps51/Vps67 Lyase_1 PF00206.15 OAJ08978.1 - 5.6e-118 393.6 0.1 8.3e-118 393.1 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 OAJ08978.1 - 9.3e-20 70.4 0.0 2.9e-19 68.8 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.7 OAJ08978.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain GLTSCR1 PF15249.1 OAJ08979.1 - 1.3e-10 41.3 0.0 2.8e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Glioma tumor suppressor candidate region NAD_binding_10 PF13460.1 OAJ08985.1 - 3.9e-18 66.1 0.0 5.5e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAJ08985.1 - 2.4e-05 23.9 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 OAJ08985.1 - 0.0022 17.3 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family TAP42 PF04177.7 OAJ08986.1 - 6.2e-59 199.6 0.0 2.7e-58 197.5 0.0 1.7 1 1 0 1 1 1 1 TAP42-like family Nop PF01798.13 OAJ08986.1 - 0.054 12.8 0.5 0.12 11.7 0.3 1.5 1 0 0 1 1 1 0 Putative snoRNA binding domain rve PF00665.21 OAJ08995.1 - 3.9e-21 75.3 0.2 1.2e-20 73.8 0.1 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ08995.1 - 3.4e-13 49.4 0.0 7.7e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 OAJ08995.1 - 0.0025 17.2 0.0 0.0068 15.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 OAJ08995.1 - 0.0073 16.1 2.2 0.017 15.0 1.6 1.7 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.1 OAJ08995.1 - 0.0074 16.0 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAJ08995.1 - 0.17 12.4 0.0 0.74 10.3 0.0 2.1 1 0 0 1 1 1 0 Aspartyl protease OPT PF03169.10 OAJ08998.1 - 4.7e-160 534.0 52.1 5.6e-160 533.7 36.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4083 PF13314.1 OAJ08998.1 - 0.13 12.0 0.2 0.37 10.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) MFS_1 PF07690.11 OAJ09008.1 - 2.5e-40 138.2 27.9 1.1e-36 126.3 6.2 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ09008.1 - 2.6e-10 39.4 2.3 2.6e-10 39.4 1.6 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter COX2-transmemb PF09125.5 OAJ09008.1 - 0.32 10.5 0.0 0.32 10.5 0.0 2.4 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane Phage_integrase PF00589.17 OAJ09014.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Phage integrase family DUF390 PF04094.9 OAJ09014.1 - 0.018 13.1 0.5 0.025 12.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) RVT_1 PF00078.22 OAJ09015.1 - 0.0028 17.0 0.0 0.0083 15.5 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Amidase PF01425.16 OAJ09015.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Amidase F-box-like PF12937.2 OAJ09019.1 - 0.001 18.7 0.6 0.0023 17.6 0.4 1.6 1 0 0 1 1 1 1 F-box-like TFIID-31kDa PF02291.10 OAJ09029.1 - 7e-39 132.5 0.0 1e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 OAJ09029.1 - 0.0039 16.9 0.0 0.0075 15.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated MAD PF05557.8 OAJ09030.1 - 7.4e-34 116.9 45.9 2.6e-25 88.6 9.5 3.0 2 1 0 2 2 2 2 Mitotic checkpoint protein ATG16 PF08614.6 OAJ09030.1 - 0.0029 17.4 23.4 0.0029 17.4 16.2 5.5 2 2 1 3 3 3 1 Autophagy protein 16 (ATG16) COG5 PF10392.4 OAJ09030.1 - 0.0039 17.1 5.1 0.0039 17.1 3.5 3.2 3 0 0 3 3 3 1 Golgi transport complex subunit 5 KIAA1430 PF13879.1 OAJ09030.1 - 0.029 14.7 0.0 0.029 14.7 0.0 2.9 2 1 1 3 3 3 0 KIAA1430 homologue Pox_G5 PF04599.7 OAJ09030.1 - 0.61 8.7 2.0 1.6 7.3 1.4 1.6 1 0 0 1 1 1 0 Poxvirus G5 protein Reo_sigmaC PF04582.7 OAJ09030.1 - 0.81 8.8 17.6 0.3 10.2 1.1 4.6 4 1 1 5 5 5 0 Reovirus sigma C capsid protein Orthopox_A5L PF06193.6 OAJ09030.1 - 1 9.3 14.0 15 5.4 5.9 3.5 2 2 0 2 2 2 0 Orthopoxvirus A5L protein-like DUF3037 PF11236.3 OAJ09030.1 - 1.6 8.8 7.4 0.51 10.4 0.6 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3037) HALZ PF02183.13 OAJ09030.1 - 9.5 6.0 34.4 0.49 10.1 1.5 6.5 7 0 0 7 7 7 0 Homeobox associated leucine zipper DLH PF01738.13 OAJ09035.1 - 3.7e-19 68.8 0.1 4.7e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 OAJ09035.1 - 8.7e-07 28.7 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family SOR_SNZ PF01680.12 OAJ09036.1 - 8.2e-115 381.6 5.9 1.2e-114 381.0 4.1 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 OAJ09036.1 - 1.2e-06 27.8 7.9 3.7e-05 22.9 0.5 2.6 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 OAJ09036.1 - 0.002 17.0 0.9 0.71 8.6 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 OAJ09036.1 - 0.033 13.4 0.1 0.65 9.2 0.0 2.3 2 0 0 2 2 2 0 Histidine biosynthesis protein NMO PF03060.10 OAJ09036.1 - 0.035 13.2 4.8 0.078 12.1 0.1 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase IGPS PF00218.16 OAJ09036.1 - 0.093 11.7 0.1 0.82 8.6 0.0 2.4 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase API5 PF05918.6 OAJ09040.1 - 0.039 12.4 1.5 0.046 12.2 1.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Utp11 PF03998.8 OAJ09040.1 - 0.039 13.7 2.2 0.045 13.5 1.5 1.1 1 0 0 1 1 1 0 Utp11 protein UPF0257 PF06788.8 OAJ09040.1 - 0.047 12.9 0.2 0.062 12.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0257) ACCA PF03255.9 OAJ09040.1 - 0.19 11.3 1.7 0.26 10.8 0.8 1.5 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ADIP PF11559.3 OAJ09040.1 - 0.22 11.4 6.8 0.17 11.8 3.9 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3782 PF12644.2 OAJ09040.1 - 0.27 11.0 1.7 1.9 8.3 1.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) WD40 PF00400.27 OAJ09046.1 - 5e-15 54.7 5.8 1.8e-06 27.6 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Spore_coat_CotO PF14153.1 OAJ09053.1 - 0.0011 18.4 8.0 0.0014 18.0 5.5 1.3 1 0 0 1 1 1 1 Spore coat protein CotO SAPS PF04499.10 OAJ09053.1 - 0.0013 17.4 5.3 0.0018 16.9 3.7 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Sec62 PF03839.11 OAJ09053.1 - 0.058 12.7 2.6 0.087 12.2 1.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4407 PF14362.1 OAJ09053.1 - 0.097 11.6 13.5 0.16 10.9 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BUD22 PF09073.5 OAJ09053.1 - 0.13 11.3 24.4 0.21 10.6 16.9 1.3 1 0 0 1 1 1 0 BUD22 Ycf1 PF05758.7 OAJ09053.1 - 0.29 8.8 13.5 0.39 8.3 9.4 1.1 1 0 0 1 1 1 0 Ycf1 CobT PF06213.7 OAJ09053.1 - 0.59 9.2 24.6 0.85 8.6 17.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mem_trans PF03547.13 OAJ09053.1 - 1 7.5 3.5 1.6 6.9 2.4 1.4 1 0 0 1 1 1 0 Membrane transport protein Merozoite_SPAM PF07133.6 OAJ09053.1 - 1.3 8.9 30.1 2 8.3 20.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RR_TM4-6 PF06459.7 OAJ09053.1 - 2.1 8.1 17.3 3.7 7.3 12.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.7 OAJ09053.1 - 3.5 5.4 32.1 4.8 4.9 22.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 OAJ09053.1 - 4.6 6.5 27.8 7.3 5.8 19.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Fe_hyd_lg_C PF02906.9 OAJ09054.1 - 6.3e-57 193.0 0.1 7.7e-56 189.4 0.1 2.4 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SR-25 PF10500.4 OAJ09054.1 - 6 6.2 11.3 5.8 6.3 4.2 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RVT_2 PF07727.9 OAJ09063.1 - 3.8e-88 294.6 0.0 6e-88 293.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09063.1 - 1.2e-28 99.5 0.0 3.4e-28 98.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ09063.1 - 3.2e-06 26.6 0.0 7.1e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ09063.1 - 6e-05 22.4 0.1 0.00022 20.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain UBN2 PF14223.1 OAJ09064.1 - 4.1e-05 23.3 0.0 7.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ09064.1 - 0.019 14.9 4.0 0.03 14.2 2.7 1.4 1 0 0 1 1 1 0 Zinc knuckle eIF-3_zeta PF05091.7 OAJ09073.1 - 1.1e-09 37.5 0.0 1.3e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BCAS2 PF05700.6 OAJ09074.1 - 1.8e-33 115.8 0.8 2.1e-33 115.6 0.5 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) CASP_C PF08172.7 OAJ09074.1 - 0.00081 18.4 0.0 0.0015 17.5 0.0 1.5 1 0 0 1 1 1 1 CASP C terminal T2SE_Nter PF05157.10 OAJ09074.1 - 0.007 16.4 0.2 0.11 12.5 0.1 2.5 1 1 2 3 3 3 1 Type II secretion system (T2SS), protein E, N-terminal domain Mak10 PF04112.8 OAJ09075.1 - 0.046 12.9 0.1 0.092 11.9 0.1 1.5 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Fun_ATP-synt_8 PF05933.8 OAJ09075.1 - 1.3 9.1 5.5 0.43 10.6 0.6 2.4 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) Glyco_hydro_47 PF01532.15 OAJ09082.1 - 2.2e-82 277.1 0.0 2.7e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Tfb4 PF03850.9 OAJ09083.1 - 5.4e-34 117.7 13.1 4.9e-19 68.6 5.6 4.0 2 1 1 3 3 3 3 Transcription factor Tfb4 Prenyltrans PF00432.16 OAJ09089.1 - 0.034 13.7 0.2 0.067 12.7 0.1 1.4 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Phage_integrase PF00589.17 OAJ09090.1 - 0.0029 17.2 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 OAJ09090.1 - 0.0033 17.5 0.0 0.011 15.8 0.0 1.9 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Na_H_Exchanger PF00999.16 OAJ09094.1 - 8.7e-68 228.5 50.1 1.3e-67 228.0 34.7 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TspO_MBR PF03073.10 OAJ09094.1 - 0.021 14.3 11.2 0.011 15.3 5.2 2.3 1 1 1 2 2 2 0 TspO/MBR family DnaJ_CXXCXGXG PF00684.14 OAJ09099.1 - 8.1e-05 22.5 4.0 0.035 14.1 0.2 2.3 2 0 0 2 2 2 2 DnaJ central domain PADR1 PF08063.7 OAJ09099.1 - 3.4 7.1 8.6 0.6 9.5 1.0 2.4 3 0 0 3 3 3 0 PADR1 (NUC008) domain tRNA_int_endo PF01974.12 OAJ09100.1 - 1.6e-19 69.4 0.1 3e-19 68.5 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 OAJ09100.1 - 0.0037 16.7 0.6 0.0088 15.5 0.4 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain PQ-loop PF04193.9 OAJ09101.1 - 1.7e-28 97.9 9.2 3.4e-17 61.7 1.5 2.4 2 0 0 2 2 2 2 PQ loop repeat Frag1 PF10277.4 OAJ09101.1 - 0.00025 20.6 6.3 0.00038 20.0 4.4 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Mg_trans_NIPA PF05653.9 OAJ09101.1 - 0.0048 15.9 3.0 0.0066 15.4 1.4 1.6 1 1 1 2 2 2 1 Magnesium transporter NIPA Arteri_Gl PF00951.13 OAJ09101.1 - 0.011 15.3 0.5 0.021 14.4 0.4 1.4 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein DUF998 PF06197.8 OAJ09101.1 - 0.025 13.8 7.2 0.97 8.7 0.9 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF998) MARVEL PF01284.18 OAJ09101.1 - 0.027 14.3 0.8 0.027 14.3 0.5 2.4 2 1 0 2 2 2 0 Membrane-associating domain DUF2781 PF10914.3 OAJ09101.1 - 0.038 13.7 1.4 0.056 13.2 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) Intg_mem_TP0381 PF09529.5 OAJ09101.1 - 0.25 10.5 4.4 0.05 12.8 0.7 1.5 2 0 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) DUF1345 PF07077.6 OAJ09101.1 - 0.27 10.7 3.9 0.45 9.9 0.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1345) DUF1218 PF06749.7 OAJ09101.1 - 0.86 10.0 4.7 0.42 11.0 0.9 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1218) DUF4149 PF13664.1 OAJ09101.1 - 3.1 7.9 6.8 0.2 11.7 0.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) NIR_SIR PF01077.17 OAJ09107.1 - 2e-29 101.9 0.1 3.9e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 OAJ09107.1 - 3.2e-21 76.1 0.0 6.5e-21 75.1 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 OAJ09107.1 - 4.3e-15 55.2 0.0 3.3e-14 52.4 0.0 2.3 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.22 OAJ09107.1 - 1.1e-13 51.3 0.4 1.1e-13 51.3 0.3 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 OAJ09107.1 - 3.1e-13 49.5 5.0 8.2e-12 45.0 3.7 2.6 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.12 OAJ09107.1 - 5.5e-11 41.9 0.0 1e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.21 OAJ09107.1 - 7.5e-11 41.4 0.2 3.2e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 OAJ09107.1 - 4.5e-05 23.6 1.4 0.0016 18.5 0.0 2.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ09107.1 - 0.0011 18.8 3.5 1.2 8.9 0.0 3.3 2 1 1 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 OAJ09107.1 - 0.0015 17.5 4.8 0.071 11.9 0.2 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ09107.1 - 0.003 16.4 0.9 1.4 7.6 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 OAJ09107.1 - 0.0094 15.9 0.8 0.04 13.9 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 OAJ09107.1 - 0.025 14.5 2.7 1.8 8.6 0.0 3.3 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_7 PF13241.1 OAJ09107.1 - 0.031 14.5 0.2 15 5.8 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 OAJ09107.1 - 0.1 11.4 0.2 4.8 5.9 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A ThiF PF00899.16 OAJ09107.1 - 0.27 11.0 2.2 1.5 8.6 0.1 2.4 2 0 0 2 2 2 0 ThiF family Glyco_hydro_15 PF00723.16 OAJ09113.1 - 1.2e-79 268.0 0.1 1.5e-79 267.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 NAC PF01849.13 OAJ09114.1 - 1.7e-18 65.9 0.0 2.9e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 NAC domain TMEM154 PF15102.1 OAJ09118.1 - 0.057 13.1 0.0 0.057 13.1 0.0 2.7 3 0 0 3 3 3 0 TMEM154 protein family RAB3GAP2_N PF14655.1 OAJ09118.1 - 2.6 6.9 11.0 6.4 5.6 0.8 2.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TSA PF03249.8 OAJ09119.1 - 9.3 4.6 9.3 15 3.9 6.4 1.3 1 0 0 1 1 1 0 Type specific antigen FA_desaturase PF00487.19 OAJ09122.1 - 3.1e-13 49.7 7.0 4.1e-13 49.3 4.9 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3425 PF11905.3 OAJ09124.1 - 1.4e-09 37.9 1.3 1.4e-09 37.9 0.9 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 OAJ09124.1 - 4.1e-08 33.0 5.5 4.1e-08 33.0 3.8 2.2 2 1 0 2 2 2 1 bZIP transcription factor UCR_14kD PF02271.11 OAJ09124.1 - 0.1 12.3 0.4 0.18 11.5 0.3 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit bZIP_2 PF07716.10 OAJ09124.1 - 0.25 11.1 8.8 0.56 10.0 3.3 2.6 1 1 1 2 2 2 0 Basic region leucine zipper FUSC PF04632.7 OAJ09124.1 - 0.5 8.7 4.1 0.86 7.9 2.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_C50 PF03568.12 OAJ09128.1 - 1.9e-75 253.9 0.0 2.4e-75 253.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C50 Ribosomal_L6 PF00347.18 OAJ09129.1 - 6.4e-19 68.2 0.0 1e-12 48.3 0.0 3.6 4 0 0 4 4 4 2 Ribosomal protein L6 DUF2106 PF09879.4 OAJ09134.1 - 0.032 13.5 0.1 0.053 12.8 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) WD40 PF00400.27 OAJ09138.1 - 2e-25 87.6 3.0 2.7e-07 30.2 0.0 6.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Peptidase_S8 PF00082.17 OAJ09142.1 - 3.1e-41 141.4 9.2 3.6e-40 137.8 6.4 2.3 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 OAJ09142.1 - 9.4e-08 32.4 2.0 1.8e-07 31.5 0.0 2.3 3 0 0 3 3 3 1 Fn3-like domain (DUF1034) PA PF02225.17 OAJ09142.1 - 0.0039 16.8 0.1 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 PA domain Pkinase PF00069.20 OAJ09146.1 - 1.3e-47 162.1 0.0 2.1e-46 158.1 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ09146.1 - 7.9e-26 90.6 0.0 2.1e-25 89.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ09146.1 - 0.00047 19.9 0.0 0.00047 19.9 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Med15 PF09606.5 OAJ09146.1 - 0.12 10.5 28.7 0.28 9.3 19.9 1.6 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal YrbL-PhoP_reg PF10707.4 OAJ09146.1 - 0.31 10.3 0.0 0.31 10.3 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pinin_SDK_memA PF04696.8 OAJ09146.1 - 0.49 9.9 13.4 0.48 10.0 7.9 1.9 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Ycf1 PF05758.7 OAJ09146.1 - 7.2 4.1 6.0 10 3.6 4.1 1.1 1 0 0 1 1 1 0 Ycf1 DUF4337 PF14235.1 OAJ09150.1 - 0.18 11.6 10.2 0.015 15.0 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) MTBP_C PF14920.1 OAJ09150.1 - 7.6 5.9 11.1 34 3.8 7.7 2.1 1 1 0 1 1 1 0 MDM2-binding Cytochrom_B_N PF00033.14 OAJ09151.1 - 0.0029 16.9 4.4 0.005 16.2 3.1 1.5 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB 7tm_7 PF08395.7 OAJ09151.1 - 0.1 11.5 0.8 0.15 11.0 0.6 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Ni_hydr_CYTB PF01292.15 OAJ09151.1 - 0.13 11.6 4.8 0.19 11.0 3.0 1.5 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF2628 PF10947.3 OAJ09151.1 - 5.6 6.8 7.2 4.1 7.2 2.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2628) Pantoate_ligase PF02569.10 OAJ09160.1 - 8.2e-81 270.8 0.0 8e-80 267.5 0.0 2.0 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase BPL_N PF09825.4 OAJ09165.1 - 3.7e-78 262.8 0.0 5.1e-78 262.4 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 OAJ09165.1 - 1.2e-12 47.9 0.0 2.4e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family vMSA PF00695.14 OAJ09168.1 - 0.1 11.7 0.2 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus AMP-binding PF00501.23 OAJ09172.1 - 2.5e-81 273.2 0.0 2.9e-81 272.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ09172.1 - 4.6e-12 46.6 0.1 9.2e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain cwf21 PF08312.7 OAJ09174.1 - 4.7e-16 58.3 3.5 4.7e-16 58.3 2.4 2.8 2 1 0 2 2 2 1 cwf21 domain GMC_oxred_N PF00732.14 OAJ09179.1 - 1.7e-60 204.7 0.0 2.2e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ09179.1 - 5e-29 101.4 0.0 9.6e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAJ09179.1 - 1.2e-08 34.2 0.3 1.1e-05 24.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ09179.1 - 1.2e-06 28.4 0.0 1.8e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAJ09179.1 - 6.6e-06 25.2 0.1 9.8e-05 21.3 0.1 2.3 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 OAJ09179.1 - 9.6e-06 25.7 0.0 0.0013 18.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAJ09179.1 - 4.2e-05 22.6 0.1 0.0001 21.3 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 OAJ09179.1 - 0.0027 16.8 0.1 0.0055 15.8 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 OAJ09179.1 - 0.0027 17.6 0.0 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ09179.1 - 0.062 11.7 0.6 0.16 10.3 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 OAJ09179.1 - 0.064 11.8 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 OAJ09179.1 - 0.082 12.6 0.1 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Alpha_GJ PF03229.8 OAJ09179.1 - 6.8 7.0 16.3 5.9 7.2 2.3 2.6 2 0 0 2 2 2 0 Alphavirus glycoprotein J Pal1 PF08316.6 OAJ09185.1 - 6.8e-17 62.2 1.6 1.5e-16 61.1 1.0 1.7 1 1 0 1 1 1 1 Pal1 cell morphology protein PPP4R2 PF09184.6 OAJ09186.1 - 4.1e-14 52.8 0.0 4.1e-14 52.8 0.0 3.0 3 0 0 3 3 3 1 PPP4R2 PTS_EIIA_2 PF00359.17 OAJ09194.1 - 0.065 12.9 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 RVT_1 PF00078.22 OAJ09204.1 - 7.3e-22 77.7 0.1 1.5e-21 76.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09204.1 - 3.5e-19 69.0 0.0 6.7e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 OAJ09204.1 - 7.9e-16 57.4 0.2 1.7e-15 56.4 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 OAJ09204.1 - 0.00064 19.0 0.0 0.0013 18.0 0.0 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Mtf2_C PF14061.1 OAJ09204.1 - 0.33 10.8 1.5 0.91 9.4 0.4 2.1 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Exo_endo_phos_2 PF14529.1 OAJ09206.1 - 0.00071 19.1 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Speriolin_N PF15058.1 OAJ09214.1 - 0.1 12.4 0.0 0.31 10.9 0.0 1.7 1 1 1 2 2 2 0 Speriolin N terminus Ferritin PF00210.19 OAJ09216.1 - 0.047 13.4 0.1 0.054 13.2 0.1 1.1 1 0 0 1 1 1 0 Ferritin-like domain 4HBT PF03061.17 OAJ09217.1 - 2.3e-06 27.6 0.1 0.022 14.8 0.0 2.9 2 1 0 2 2 2 2 Thioesterase superfamily CTF_NFI PF00859.13 OAJ09217.1 - 0.00077 19.3 2.3 0.00077 19.3 1.6 2.2 2 0 0 2 2 2 1 CTF/NF-I family transcription modulation region DUF515 PF04415.7 OAJ09217.1 - 1.6 6.8 4.2 2.4 6.2 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SR-25 PF10500.4 OAJ09217.1 - 2.9 7.3 12.9 0.17 11.3 5.3 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Syntaxin-18_N PF10496.4 OAJ09225.1 - 1.6e-06 27.8 0.6 1.8e-05 24.4 0.0 2.9 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Motilin_assoc PF04643.7 OAJ09225.1 - 0.043 13.3 0.3 0.094 12.2 0.2 1.6 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide Abhydrolase_3 PF07859.8 OAJ09226.1 - 6.9e-27 94.3 0.0 1.2e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAJ09226.1 - 1.8e-07 30.5 0.1 0.0017 17.5 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAJ09226.1 - 1.7e-05 24.5 0.3 5.3e-05 23.0 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAJ09226.1 - 0.00057 19.3 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Ribosomal_60s PF00428.14 OAJ09226.1 - 0.015 15.6 16.5 0.034 14.5 8.1 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glyco_transf_22 PF03901.12 OAJ09227.1 - 2e-27 96.2 9.3 2.4e-27 95.9 6.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Peptidase_M18 PF02127.10 OAJ09230.1 - 9.1e-153 508.7 0.0 1.2e-152 508.3 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 OAJ09230.1 - 0.00013 20.8 0.0 0.031 13.0 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Exo_endo_phos PF03372.18 OAJ09231.1 - 7e-19 68.7 0.5 1e-18 68.2 0.3 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family IATP PF04568.7 OAJ09231.1 - 0.13 12.3 0.5 0.33 10.9 0.3 1.7 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP RRM_1 PF00076.17 OAJ09243.1 - 2.3e-23 81.5 0.0 3.4e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ09243.1 - 1.2e-18 66.8 0.0 1.7e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ09243.1 - 2.6e-11 43.2 0.0 3.8e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HsbA PF12296.3 OAJ09244.1 - 3e-13 49.7 13.2 4.7e-13 49.0 9.2 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Pox_A6 PF04924.7 OAJ09244.1 - 0.041 12.6 0.7 0.043 12.5 0.5 1.1 1 0 0 1 1 1 0 Poxvirus A6 protein FUN14 PF04930.10 OAJ09244.1 - 2.3 8.5 5.2 14 6.0 3.6 2.4 1 1 0 1 1 1 0 FUN14 family Ribosomal_L28e PF01778.12 OAJ09244.1 - 3.6 7.9 6.4 2 8.8 1.7 2.2 1 1 0 2 2 2 0 Ribosomal L28e protein family Sigma70_ner PF04546.8 OAJ09247.1 - 1.2 8.7 8.6 0.12 11.9 2.5 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Vfa1 PF08432.5 OAJ09247.1 - 7.5 6.5 14.6 2 8.4 2.2 2.5 2 1 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Med14 PF08638.6 OAJ09253.1 - 3.9e-37 127.3 0.0 7.4e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 Collagen PF01391.13 OAJ09258.1 - 0.0004 19.8 2.6 0.00056 19.4 1.8 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) CAP18_C PF12153.3 OAJ09258.1 - 0.11 12.1 1.2 0.23 11.1 0.8 1.5 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) HsbA PF12296.3 OAJ09259.1 - 2.8e-15 56.2 4.9 4.7e-15 55.5 3.4 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A TIP49 PF06068.8 OAJ09265.1 - 4.5e-176 585.4 0.0 6.5e-176 584.9 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 OAJ09265.1 - 1.9e-10 41.0 0.1 3.8e-06 27.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 OAJ09265.1 - 4.7e-09 35.6 0.6 1.8e-05 23.9 0.0 2.8 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 OAJ09265.1 - 5.2e-07 29.8 0.2 0.056 13.5 0.1 2.7 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAJ09265.1 - 3.5e-05 23.8 0.0 0.0015 18.5 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 OAJ09265.1 - 4.2e-05 23.2 0.2 0.014 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 OAJ09265.1 - 5.3e-05 22.9 0.1 0.0003 20.4 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 OAJ09265.1 - 0.0002 21.3 0.1 0.00038 20.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAJ09265.1 - 0.00027 20.3 0.0 0.00055 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 OAJ09265.1 - 0.0033 16.6 0.1 0.24 10.5 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 OAJ09265.1 - 0.0036 16.7 0.2 0.012 14.9 0.1 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 OAJ09265.1 - 0.011 15.6 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAJ09265.1 - 0.017 14.7 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 OAJ09265.1 - 0.018 14.9 0.0 5.1 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 OAJ09265.1 - 0.019 14.4 0.1 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.4 OAJ09265.1 - 0.034 13.1 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 OAJ09265.1 - 0.056 12.5 0.4 0.12 11.4 0.3 1.5 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 OAJ09265.1 - 0.068 12.8 0.1 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 OAJ09265.1 - 0.068 13.9 0.0 0.22 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.10 OAJ09265.1 - 0.085 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DDE_3 PF13358.1 OAJ09266.1 - 2.8e-16 59.5 0.0 4.9e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAJ09266.1 - 0.00037 21.2 0.1 0.0011 19.7 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.1 OAJ09266.1 - 0.06 12.8 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Arteri_nucleo PF01481.11 OAJ09266.1 - 0.095 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein AAA_30 PF13604.1 OAJ09266.1 - 0.14 11.7 0.1 6.3 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF3661 PF12400.3 OAJ09273.1 - 2.9e-39 134.1 5.8 4.1e-39 133.6 4.1 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein SR-25 PF10500.4 OAJ09277.1 - 0.003 17.0 13.8 0.003 17.0 9.6 3.4 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein RAP1 PF07218.6 OAJ09277.1 - 1.1 7.2 8.1 2.1 6.3 5.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Phage_integrase PF00589.17 OAJ09278.1 - 5.2e-06 26.2 0.0 7.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Ribosomal_L23 PF00276.15 OAJ09284.1 - 2.7e-08 33.6 0.0 1.7e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L23 Sec1 PF00995.18 OAJ09286.1 - 9.2e-09 34.4 0.0 1e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF1967 PF09269.6 OAJ09287.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) TPR_12 PF13424.1 OAJ09293.1 - 0.018 14.9 0.2 0.06 13.2 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ09293.1 - 0.12 12.3 0.8 4.9 7.2 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Laminin_II PF06009.7 OAJ09294.1 - 0.012 15.3 1.3 0.024 14.3 0.2 1.8 1 1 1 2 2 2 0 Laminin Domain II DUF1465 PF07323.7 OAJ09294.1 - 0.029 13.9 3.6 0.82 9.2 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) GP41 PF00517.12 OAJ09294.1 - 0.036 13.6 0.0 0.06 12.8 0.0 1.4 1 1 0 1 1 1 0 Retroviral envelope protein GreA_GreB_N PF03449.10 OAJ09294.1 - 0.041 13.9 1.8 0.097 12.7 1.1 1.7 1 1 1 2 2 2 0 Transcription elongation factor, N-terminal Cep57_CLD PF14073.1 OAJ09294.1 - 0.08 12.7 1.2 0.096 12.5 0.8 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Seryl_tRNA_N PF02403.17 OAJ09294.1 - 0.088 12.8 3.2 0.23 11.4 2.2 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.3 OAJ09294.1 - 0.11 11.6 1.7 0.27 10.4 0.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Nup88 PF10168.4 OAJ09294.1 - 0.19 9.5 1.6 0.23 9.2 1.1 1.0 1 0 0 1 1 1 0 Nuclear pore component Dor1 PF04124.7 OAJ09294.1 - 0.37 9.1 2.9 2.1 6.7 0.2 2.0 1 1 1 2 2 2 0 Dor1-like family DnaJ-X PF14308.1 OAJ09301.1 - 8.7e-46 155.7 1.5 2e-45 154.5 1.0 1.6 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 OAJ09301.1 - 1.2e-25 88.9 0.4 1.2e-25 88.9 0.3 2.5 3 0 0 3 3 3 1 DnaJ domain LRR_8 PF13855.1 OAJ09302.1 - 0.03 14.0 0.1 0.35 10.6 0.0 2.9 3 0 0 3 3 3 0 Leucine rich repeat SGT1 PF07093.6 OAJ09305.1 - 2.1e-41 142.0 38.7 3.7e-36 124.6 0.3 2.6 1 1 1 2 2 2 2 SGT1 protein Flavin_Reduct PF01613.13 OAJ09306.1 - 2.3e-31 108.7 0.5 3.4e-31 108.1 0.4 1.3 1 0 0 1 1 1 1 Flavin reductase like domain ADK PF00406.17 OAJ09307.1 - 8.6e-43 145.8 0.0 1.1e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 OAJ09307.1 - 6.1e-12 45.0 0.0 1.3e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid Zeta_toxin PF06414.7 OAJ09307.1 - 0.00097 18.2 0.0 0.002 17.2 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 OAJ09307.1 - 0.0038 18.0 0.0 0.0059 17.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ09307.1 - 0.0059 16.4 0.0 0.016 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ09307.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain Asp PF00026.18 OAJ09313.1 - 1.4e-48 165.7 0.0 3.3e-48 164.5 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ09313.1 - 0.00014 21.8 2.7 0.00038 20.4 0.3 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal RVP PF00077.15 OAJ09313.1 - 0.14 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease SHR3_chaperone PF08229.6 OAJ09314.1 - 2e-30 105.2 2.1 8.1e-30 103.2 1.5 1.8 1 1 0 1 1 1 1 ER membrane protein SH3 DUF2269 PF10027.4 OAJ09314.1 - 0.07 12.9 3.2 0.28 10.9 0.7 2.4 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2269) Ras PF00071.17 OAJ09315.1 - 1.2e-15 57.2 0.0 1.5e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Ras family F-box-like PF12937.2 OAJ09321.1 - 0.033 13.9 0.4 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 F-box-like RNA_pol_Rpb1_1 PF04997.7 OAJ09339.1 - 1.9e-97 326.5 0.0 2.1e-97 326.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 OAJ09339.1 - 9e-14 51.7 0.0 1.6e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RrnaAD PF00398.15 OAJ09340.1 - 5.3e-11 42.0 0.0 1.7e-10 40.4 0.0 1.7 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCI PF01399.22 OAJ09341.1 - 7.8e-20 71.1 0.0 2.1e-19 69.7 0.0 1.8 1 0 0 1 1 1 1 PCI domain HTH_27 PF13463.1 OAJ09341.1 - 0.0079 16.4 0.0 0.026 14.8 0.0 1.9 1 0 0 1 1 1 1 Winged helix DNA-binding domain TPR_14 PF13428.1 OAJ09341.1 - 0.086 13.5 3.6 5.3 7.9 1.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ09341.1 - 0.19 11.8 2.6 1 9.4 0.8 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ09341.1 - 0.39 11.0 3.3 6.5 7.1 0.9 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ09341.1 - 0.42 11.1 3.6 15 6.3 1.5 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Hus1 PF04005.7 OAJ09347.1 - 2.5e-72 243.3 0.1 3.7e-72 242.7 0.1 1.3 1 0 0 1 1 1 1 Hus1-like protein DUF1681 PF07933.9 OAJ09348.1 - 5.4e-51 172.3 0.0 6.3e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DUF500 PF04366.7 OAJ09358.1 - 1.7e-43 147.0 1.0 1e-41 141.3 0.1 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF500) AhpC-TSA PF00578.16 OAJ09363.1 - 8.7e-22 77.1 0.0 1.4e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 OAJ09363.1 - 5.6e-14 51.9 0.0 8.4e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin MSA-2c PF12238.3 OAJ09363.1 - 1.5 8.4 10.5 2.3 7.8 7.3 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c MSP1_C PF07462.6 OAJ09363.1 - 5.8 5.1 8.1 7.6 4.7 5.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus rve PF00665.21 OAJ09367.1 - 1.9e-14 53.8 0.0 5.6e-14 52.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ09367.1 - 5.3e-12 45.5 0.2 1.4e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 OAJ09367.1 - 9.1e-08 32.1 0.0 1.9e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ09367.1 - 1.8e-07 30.8 0.0 4.5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAJ09367.1 - 1.9e-06 28.2 0.0 3.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.19 OAJ09367.1 - 0.00012 21.6 0.8 0.00038 20.0 0.2 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 OAJ09367.1 - 0.00053 20.0 0.2 0.0023 17.9 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAJ09367.1 - 0.00086 19.1 3.5 0.0024 17.7 2.4 1.8 1 0 0 1 1 1 1 Zinc knuckle NAD_binding_10 PF13460.1 OAJ09373.1 - 0.00049 20.1 0.3 0.016 15.2 0.2 2.7 1 1 0 1 1 1 1 NADH(P)-binding RVT_2 PF07727.9 OAJ09377.1 - 7.9e-89 296.8 0.0 1.2e-88 296.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09377.1 - 7.5e-26 90.5 0.0 2e-25 89.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ09377.1 - 1.2e-05 24.7 0.0 4.4e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ09377.1 - 3.4e-05 23.3 0.3 7.5e-05 22.2 0.2 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 OAJ09378.1 - 0.00061 19.5 5.7 0.001 18.9 3.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ09378.1 - 0.0013 18.3 1.2 0.0027 17.3 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 OAJ09378.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.1 OAJ09378.1 - 0.072 12.5 2.2 0.13 11.7 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 OAJ09378.1 - 2.2 7.8 10.7 0.35 10.3 4.5 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Histone PF00125.19 OAJ09384.1 - 8.6e-14 51.4 0.1 1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ09384.1 - 0.00012 22.2 0.0 0.00016 21.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 OAJ09384.1 - 0.00024 20.9 0.1 0.00034 20.4 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 OAJ09384.1 - 0.00077 19.4 0.1 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 OAJ09384.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T HA2 PF04408.18 OAJ09385.1 - 1.9e-24 85.6 0.0 6.4e-24 83.9 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 OAJ09385.1 - 4.1e-23 81.3 0.0 1.3e-22 79.7 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 OAJ09385.1 - 6.4e-13 48.3 0.0 1.5e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ09385.1 - 8.9e-09 35.0 0.1 2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ09385.1 - 3.6e-06 27.1 0.1 9.5e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 OAJ09385.1 - 0.0011 17.9 0.0 0.0023 16.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 OAJ09385.1 - 0.0049 16.9 0.1 0.031 14.3 0.0 2.3 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 OAJ09385.1 - 0.011 15.5 0.1 0.083 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 OAJ09385.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 KaiC SRP54 PF00448.17 OAJ09385.1 - 0.014 14.8 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ResIII PF04851.10 OAJ09385.1 - 0.022 14.6 0.0 8.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.7 OAJ09385.1 - 0.082 12.5 0.4 0.85 9.2 0.0 2.4 3 0 0 3 3 3 0 NACHT domain Arch_ATPase PF01637.13 OAJ09385.1 - 0.086 12.5 0.1 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Myosin_head PF00063.16 OAJ09385.1 - 0.11 10.5 0.0 0.17 9.9 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) RAP1 PF07218.6 OAJ09385.1 - 1.5 6.8 4.1 2.3 6.1 2.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PTS_2-RNA PF01885.11 OAJ09390.1 - 7.5e-43 146.0 0.0 7.7e-42 142.7 0.0 2.4 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family FXR1P_C PF12235.3 OAJ09390.1 - 0.018 15.1 6.6 0.018 15.1 4.6 2.9 3 1 0 3 3 3 0 Fragile X-related 1 protein C terminal GLTP PF08718.6 OAJ09391.1 - 1.2e-43 148.7 0.0 1.7e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Ribosomal_L24e PF01246.15 OAJ09392.1 - 7e-32 109.1 0.7 7e-32 109.1 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e PVL_ORF50 PF07768.6 OAJ09392.1 - 0.6 10.1 6.3 0.89 9.5 4.4 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family CLTH PF10607.4 OAJ09393.1 - 5.9e-29 100.6 0.0 7.4e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 OAJ09393.1 - 9.9e-11 41.0 0.6 1.8e-10 40.1 0.1 1.8 2 0 0 2 2 2 1 LisH Ribosomal_60s PF00428.14 OAJ09393.1 - 7.6e-06 26.2 7.1 1.8e-05 25.0 4.9 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein Nucleoplasmin PF03066.10 OAJ09393.1 - 0.0061 16.0 0.8 0.0091 15.5 0.5 1.2 1 0 0 1 1 1 1 Nucleoplasmin Myc_N PF01056.13 OAJ09393.1 - 0.049 12.7 1.6 0.077 12.1 1.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region BSP_II PF05432.6 OAJ09393.1 - 0.078 12.2 5.8 0.11 11.7 4.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Retinal PF15449.1 OAJ09393.1 - 0.099 10.2 0.4 0.12 9.9 0.2 1.1 1 0 0 1 1 1 0 Retinal protein PBP1_TM PF14812.1 OAJ09393.1 - 0.78 10.0 4.7 1.2 9.4 3.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LAT PF15234.1 OAJ09393.1 - 3.2 7.1 6.9 1.4 8.3 2.7 1.7 2 0 0 2 2 2 0 Linker for activation of T-cells Transposase_21 PF02992.9 OAJ09397.1 - 1.2e-07 31.1 0.0 2.8e-07 29.8 0.0 1.5 2 0 0 2 2 2 1 Transposase family tnp2 Leucyl-specific PF14795.1 OAJ09397.1 - 0.1 12.4 0.1 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain Myc_N PF01056.13 OAJ09398.1 - 0.59 9.2 3.5 0.92 8.6 2.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 OAJ09398.1 - 1.3 8.5 5.8 2 7.9 4.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin LSM PF01423.17 OAJ09399.1 - 5.7e-20 70.6 0.1 7.1e-20 70.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF4006 PF13179.1 OAJ09403.1 - 0.076 12.5 0.6 0.14 11.7 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) UBN2_2 PF14227.1 OAJ09409.1 - 4e-05 23.1 0.0 5.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ09409.1 - 0.003 17.3 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 OAJ09409.1 - 0.079 12.4 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) DDE_Tnp_4 PF13359.1 OAJ09415.1 - 1.1e-21 77.0 0.9 1.8e-21 76.3 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease ATG16 PF08614.6 OAJ09416.1 - 0.00096 19.0 5.8 0.0019 18.0 4.0 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Macoilin PF09726.4 OAJ09416.1 - 0.096 10.9 7.1 0.17 10.1 4.9 1.5 1 0 0 1 1 1 0 Transmembrane protein TPR_2 PF07719.12 OAJ09423.1 - 2.2e-06 27.1 7.7 0.022 14.6 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ09423.1 - 7e-06 25.4 5.1 0.023 14.2 0.1 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ09423.1 - 1.7e-05 24.2 0.4 0.034 13.9 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ09423.1 - 0.00014 21.3 10.9 0.077 12.6 0.0 5.0 4 1 2 6 6 6 2 TPR repeat DUF3856 PF12968.2 OAJ09423.1 - 0.005 16.6 1.2 2.6 7.8 0.1 3.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF3856) Apc3 PF12895.2 OAJ09423.1 - 0.0058 16.7 0.9 4.7 7.4 0.0 3.3 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Apc5 PF12862.2 OAJ09423.1 - 0.016 15.0 7.1 0.025 14.4 0.0 4.0 4 2 1 5 5 5 0 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 OAJ09423.1 - 0.02 14.8 1.1 0.02 14.8 0.8 6.8 8 2 1 9 9 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ09423.1 - 0.41 10.5 4.4 5.8 6.9 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ09423.1 - 1.1 10.1 0.0 1.1 10.1 0.0 7.6 7 2 2 9 9 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ09423.1 - 1.2 9.7 20.5 2.4 8.8 0.1 6.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ09423.1 - 2.3 8.6 12.1 4.4 7.7 0.5 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ09423.1 - 3.1 7.7 15.9 0.97 9.3 0.3 5.0 3 1 2 5 5 4 0 Tetratricopeptide repeat MutS_III PF05192.13 OAJ09423.1 - 6.5 6.4 11.6 34 4.1 4.9 3.4 1 1 1 2 2 2 0 MutS domain III RNase_PH PF01138.16 OAJ09427.1 - 1.6e-11 44.6 0.1 2.8e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF4121 PF13497.1 OAJ09429.1 - 0.043 12.8 0.1 0.06 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) Glug PF07581.7 OAJ09430.1 - 5.7 7.3 7.6 11 6.4 0.6 2.5 2 0 0 2 2 2 0 The GLUG motif Glyco_tranf_2_3 PF13641.1 OAJ09437.1 - 3.9e-25 88.9 0.0 5.6e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 OAJ09437.1 - 3.4e-09 36.2 0.1 1.2e-08 34.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 OAJ09437.1 - 3.9e-09 36.4 0.0 6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 OAJ09437.1 - 2e-06 27.6 5.7 2e-06 27.6 3.9 1.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.10 OAJ09437.1 - 0.0039 15.6 0.1 0.023 13.1 0.0 1.8 1 1 0 1 1 1 1 Chitin synthase Tropomodulin PF03250.9 OAJ09438.1 - 0.027 14.0 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Tropomodulin DUF3352 PF11832.3 OAJ09438.1 - 0.11 10.7 0.3 0.12 10.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) Pkinase PF00069.20 OAJ09445.1 - 1.1e-52 178.7 0.0 1.1e-52 178.7 0.0 3.2 4 1 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ09445.1 - 1.9e-21 76.3 0.0 1.9e-21 76.3 0.0 3.0 4 0 0 4 4 4 1 Protein tyrosine kinase HEM4 PF02602.10 OAJ09450.1 - 1.1e-16 60.7 0.7 4.5e-08 32.6 0.0 4.8 5 0 0 5 5 5 4 Uroporphyrinogen-III synthase HemD Helicase_C PF00271.26 OAJ09451.1 - 3.2e-16 58.9 0.2 1.8e-15 56.5 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ09451.1 - 4.9e-15 55.4 0.0 9.3e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ09451.1 - 2.9e-11 43.5 0.0 7.5e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 OAJ09451.1 - 2.1e-06 26.7 0.1 2.1e-06 26.7 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Dicer_dimer PF03368.9 OAJ09451.1 - 7.3e-05 22.4 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain AAA_22 PF13401.1 OAJ09451.1 - 0.00057 20.0 0.0 0.0027 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 OAJ09451.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 OAJ09451.1 - 0.013 14.5 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Helicase_C_2 PF13307.1 OAJ09451.1 - 0.022 14.7 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 Helicase C-terminal domain CALCOCO1 PF07888.6 OAJ09451.1 - 0.022 13.0 0.5 0.035 12.4 0.4 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Troponin PF00992.15 OAJ09451.1 - 0.025 14.6 2.0 0.062 13.3 1.4 1.7 1 0 0 1 1 1 0 Troponin DUF904 PF06005.7 OAJ09451.1 - 0.048 13.9 1.4 0.12 12.6 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) MRF_C2 PF13888.1 OAJ09451.1 - 0.099 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 ATP-sulfurylase PF01747.12 OAJ09457.1 - 3.1e-87 291.4 0.6 4.4e-87 290.9 0.4 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 OAJ09457.1 - 9.8e-54 181.2 0.0 1.6e-53 180.5 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 OAJ09457.1 - 2.8e-51 173.0 0.0 4.8e-51 172.3 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain RALF PF05498.6 OAJ09463.1 - 0.075 13.8 0.0 1.7 9.5 0.0 2.1 1 1 1 2 2 2 0 Rapid ALkalinization Factor (RALF) Aldedh PF00171.17 OAJ09471.1 - 5.9e-155 516.1 0.5 6.7e-155 515.9 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.20 OAJ09472.1 - 2.7e-73 246.3 0.0 3.2e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ09472.1 - 1.3e-33 116.2 0.0 3.2e-33 114.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ09472.1 - 0.0023 16.9 0.0 0.0049 15.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ09472.1 - 0.0026 16.8 0.1 0.0046 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ09472.1 - 0.064 12.9 0.1 0.18 11.5 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF418 PF04235.7 OAJ09478.1 - 0.033 13.8 0.3 0.033 13.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF418) DUF212 PF02681.9 OAJ09478.1 - 0.13 12.0 0.1 0.13 12.0 0.1 1.6 2 0 0 2 2 2 0 Divergent PAP2 family Glyco_hydro_45 PF02015.11 OAJ09483.1 - 1.9e-49 168.4 10.0 2.2e-49 168.2 6.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Glyco_hydro_45 PF02015.11 OAJ09484.1 - 1.6e-24 87.0 0.8 2.3e-24 86.6 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Asn_synthase PF00733.16 OAJ09489.1 - 3.2e-18 66.1 0.0 4.1e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase tRNA-synt_2d PF01409.15 OAJ09490.1 - 5.5e-43 146.9 0.2 3.2e-25 88.7 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 OAJ09490.1 - 4.3e-23 81.2 0.0 1e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain DUF883 PF05957.8 OAJ09491.1 - 0.037 14.4 0.4 0.037 14.4 0.3 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Nop14 PF04147.7 OAJ09491.1 - 0.66 7.8 6.6 1.2 6.9 4.5 1.4 1 0 0 1 1 1 0 Nop14-like family FLO_LFY PF01698.11 OAJ09491.1 - 9.6 4.9 7.7 2 7.1 2.8 1.7 2 0 0 2 2 2 0 Floricaula / Leafy protein Adap_comp_sub PF00928.16 OAJ09492.1 - 2e-60 204.1 0.0 2.9e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 OAJ09492.1 - 3.5e-08 33.2 0.1 6e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Fez1 PF06818.10 OAJ09499.1 - 0.00076 19.5 3.9 0.00089 19.3 2.7 1.1 1 0 0 1 1 1 1 Fez1 IncA PF04156.9 OAJ09499.1 - 0.0028 17.2 8.0 0.0077 15.8 5.6 1.6 1 1 0 1 1 1 1 IncA protein Reo_sigmaC PF04582.7 OAJ09499.1 - 0.003 16.8 5.1 0.0035 16.5 3.5 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein ATG16 PF08614.6 OAJ09499.1 - 0.0096 15.7 5.7 0.014 15.2 3.9 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Nup54 PF13874.1 OAJ09499.1 - 0.012 15.2 1.2 0.057 13.0 0.4 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 CENP-F_leu_zip PF10473.4 OAJ09499.1 - 0.013 15.3 5.5 0.051 13.4 3.7 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 OAJ09499.1 - 0.038 13.9 6.3 0.17 11.8 3.0 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 OAJ09499.1 - 0.041 12.8 3.5 0.055 12.4 2.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spectrin PF00435.16 OAJ09499.1 - 0.052 13.8 3.8 0.077 13.2 2.6 1.3 1 0 0 1 1 1 0 Spectrin repeat TPR_MLP1_2 PF07926.7 OAJ09499.1 - 0.062 13.0 9.7 0.11 12.3 6.7 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cluap1 PF10234.4 OAJ09499.1 - 0.071 12.3 3.1 0.09 11.9 2.1 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 CENP-Q PF13094.1 OAJ09499.1 - 0.077 13.0 7.4 0.17 11.8 5.1 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF812 PF05667.6 OAJ09499.1 - 0.078 11.4 4.6 0.09 11.2 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3584 PF12128.3 OAJ09499.1 - 0.098 9.9 4.7 0.13 9.5 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 OAJ09499.1 - 0.11 11.1 3.8 0.25 9.9 2.0 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 OAJ09499.1 - 0.11 12.3 7.7 2 8.3 1.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding MscS_porin PF12795.2 OAJ09499.1 - 0.11 11.7 10.5 0.32 10.2 7.3 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Mnd1 PF03962.10 OAJ09499.1 - 0.12 12.0 1.3 0.15 11.6 0.9 1.2 1 0 0 1 1 1 0 Mnd1 family BRE1 PF08647.6 OAJ09499.1 - 0.16 11.9 2.4 0.28 11.1 1.7 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase FlgM PF04316.8 OAJ09499.1 - 0.24 11.3 2.4 0.58 10.1 1.2 2.1 1 1 0 1 1 1 0 Anti-sigma-28 factor, FlgM DUF2968 PF11180.3 OAJ09499.1 - 0.24 10.7 9.1 0.33 10.3 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4140 PF13600.1 OAJ09499.1 - 0.25 11.8 11.1 1.9 8.9 3.8 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) GvpG PF05120.7 OAJ09499.1 - 0.27 11.0 2.6 0.19 11.5 0.2 1.9 2 1 0 2 2 2 0 Gas vesicle protein G GAS PF13851.1 OAJ09499.1 - 0.38 9.9 2.4 0.49 9.5 1.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cortex-I_coil PF09304.5 OAJ09499.1 - 0.42 10.6 7.6 0.55 10.3 4.9 1.5 1 1 0 1 1 1 0 Cortexillin I, coiled coil Filament PF00038.16 OAJ09499.1 - 0.7 9.3 6.2 1 8.7 2.5 1.9 1 1 1 2 2 2 0 Intermediate filament protein Seryl_tRNA_N PF02403.17 OAJ09499.1 - 1 9.3 4.3 2.1 8.4 3.0 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain GrpE PF01025.14 OAJ09499.1 - 1.2 8.6 5.1 3.3 7.2 3.5 1.6 1 1 0 1 1 1 0 GrpE HAUS-augmin3 PF14932.1 OAJ09499.1 - 1.3 8.1 5.2 1.7 7.7 3.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4231 PF14015.1 OAJ09500.1 - 1.5 8.8 7.2 1.7 8.6 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) MSP1_C PF07462.6 OAJ09500.1 - 4.1 5.6 5.5 4.2 5.6 3.8 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Myticin-prepro PF10690.4 OAJ09500.1 - 4.2 7.4 7.2 3.5 7.7 4.4 1.4 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel Ribosomal_L10 PF00466.15 OAJ09504.1 - 0.002 17.9 0.0 0.0043 16.9 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L10 Transket_pyr PF02779.19 OAJ09505.1 - 6.9e-37 126.6 0.0 1.1e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 OAJ09505.1 - 1.6e-27 95.9 0.0 2e-26 92.3 0.0 2.3 1 1 0 1 1 1 1 Transketolase, C-terminal domain MCPVI PF02993.9 OAJ09506.1 - 0.17 12.0 2.6 0.19 11.8 1.8 1.0 1 0 0 1 1 1 0 Minor capsid protein VI Cullin PF00888.17 OAJ09512.1 - 9.2e-148 493.3 0.0 2.7e-143 478.6 0.0 2.1 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 OAJ09512.1 - 4.4e-29 100.1 0.3 8.6e-29 99.1 0.2 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain Penicillinase_R PF03965.11 OAJ09512.1 - 0.02 14.9 0.0 0.091 12.8 0.0 2.2 1 0 0 1 1 1 0 Penicillinase repressor TrmB PF01978.14 OAJ09512.1 - 0.023 14.4 0.2 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF2580 PF10824.3 OAJ09519.1 - 0.049 13.9 35.7 1.4 9.3 1.1 5.8 1 1 3 5 5 5 0 Protein of unknown function (DUF2580) DUF3321 PF11968.3 OAJ09524.1 - 6.1e-44 150.2 0.0 5.3e-26 91.6 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase (DUF3321) RVT_3 PF13456.1 OAJ09526.1 - 0.054 13.2 0.1 0.087 12.6 0.1 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like UPF0183 PF03676.9 OAJ09532.1 - 2e-12 46.4 0.0 6.3e-06 25.0 0.1 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0183) TSA PF03249.8 OAJ09532.1 - 6 5.2 7.4 9.4 4.6 5.1 1.2 1 0 0 1 1 1 0 Type specific antigen PTCB-BRCT PF12738.2 OAJ09533.1 - 1.8e-30 104.5 0.5 8.8e-19 67.1 0.1 5.3 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.21 OAJ09533.1 - 6.9e-26 90.2 0.0 3.9e-12 46.1 0.0 7.1 7 1 0 7 7 7 5 BRCA1 C Terminus (BRCT) domain DnaJ PF00226.26 OAJ09536.1 - 6.6e-14 51.4 0.8 1.4e-13 50.3 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain Ras PF00071.17 OAJ09537.1 - 1.9e-56 189.9 0.3 2.4e-56 189.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ09537.1 - 1.2e-18 67.7 0.1 1.7e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ09537.1 - 2.6e-13 49.6 0.2 3.1e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ09537.1 - 6.3e-07 29.0 0.1 1.2e-06 28.0 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 OAJ09537.1 - 0.00018 20.7 0.1 0.00022 20.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 OAJ09537.1 - 0.0021 17.2 0.2 0.0024 17.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Lipase_GDSL_2 PF13472.1 OAJ09538.1 - 1.1e-06 28.8 0.3 1.5e-06 28.4 0.2 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 OAJ09538.1 - 9.9e-06 25.5 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DCR PF14047.1 OAJ09538.1 - 0.12 12.6 0.2 0.6 10.4 0.0 2.1 2 0 0 2 2 2 0 Dppa2/4 conserved region GCR1_C PF12550.3 OAJ09542.1 - 1.3e-17 63.4 0.1 2.5e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Gag_spuma PF03276.9 OAJ09542.1 - 3.8 5.7 10.9 5.7 5.1 7.6 1.2 1 0 0 1 1 1 0 Spumavirus gag protein TryThrA_C PF12319.3 OAJ09548.1 - 0.13 11.4 2.1 0.25 10.5 1.5 1.4 1 0 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal DUF2457 PF10446.4 OAJ09548.1 - 0.35 9.5 14.5 0.15 10.7 8.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Pox_Ag35 PF03286.9 OAJ09556.1 - 0.084 12.3 3.9 0.15 11.5 2.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ICAP-1_inte_bdg PF10480.4 OAJ09556.1 - 2.2 7.9 7.6 3.1 7.5 5.3 1.2 1 0 0 1 1 1 0 Beta-1 integrin binding protein AMP-binding PF00501.23 OAJ09563.1 - 1.1e-71 241.5 0.0 2e-48 164.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ09563.1 - 2e-10 41.4 0.3 2e-08 35.0 0.0 3.4 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain UDPGP PF01704.13 OAJ09564.1 - 5e-34 117.5 0.0 6.3e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase MRP-L20 PF12824.2 OAJ09575.1 - 3.7e-20 72.5 0.1 5.9e-20 71.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 GntR PF00392.16 OAJ09575.1 - 0.12 11.8 0.1 0.37 10.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_AsnC-type PF13404.1 OAJ09575.1 - 0.86 9.1 0.0 0.86 9.1 0.0 2.8 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain WD40 PF00400.27 OAJ09582.1 - 4.9e-29 99.1 1.2 4.2e-08 32.7 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 OAJ09582.1 - 7.6e-05 22.5 0.0 0.014 15.1 0.0 2.4 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DcpS_C PF11969.3 OAJ09583.1 - 7.1e-21 74.5 0.7 1.2e-20 73.9 0.5 1.3 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 OAJ09583.1 - 1.3e-08 35.2 3.6 5.5e-08 33.2 2.5 1.8 1 1 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.10 OAJ09583.1 - 0.008 15.8 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Dimer_Tnp_hAT PF05699.9 OAJ09592.1 - 5.2e-05 22.7 0.0 7.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region GCR1_C PF12550.3 OAJ09593.1 - 0.00032 20.5 0.0 0.00054 19.7 0.0 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Metal_resist PF13801.1 OAJ09593.1 - 0.0048 16.8 0.1 0.024 14.6 0.0 2.0 2 0 0 2 2 2 1 Heavy-metal resistance BNIP2 PF12496.3 OAJ09595.1 - 0.0038 17.3 1.0 0.0038 17.3 0.7 2.3 2 0 0 2 2 2 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CDC45 PF02724.9 OAJ09595.1 - 0.58 8.1 2.6 1.2 7.0 1.8 1.5 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 OAJ09595.1 - 2.2 7.8 7.0 4.8 6.7 1.0 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF3439 PF11921.3 OAJ09603.1 - 0.031 14.0 0.9 0.038 13.7 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF3446 PF11928.3 OAJ09603.1 - 3.9 7.7 13.7 0.23 11.6 2.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3446) SSP160 PF06933.6 OAJ09603.1 - 4.8 5.0 6.7 6.3 4.6 4.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ADH_N PF08240.7 OAJ09609.1 - 1.2e-27 95.8 4.1 2e-27 95.0 2.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ09609.1 - 4.3e-19 68.3 0.0 6.6e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 OAJ09609.1 - 0.013 14.7 0.1 0.021 13.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain An_peroxidase PF03098.10 OAJ09610.1 - 1.8e-11 43.1 0.0 2.3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase UCH PF00443.24 OAJ09613.1 - 2.9e-39 134.7 0.0 4e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ09613.1 - 1.1e-11 44.7 0.0 4.5e-11 42.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SUZ PF12752.2 OAJ09614.1 - 7.5e-14 52.0 0.0 7.5e-14 52.0 0.0 6.5 6 1 0 6 6 6 1 SUZ domain R3H PF01424.17 OAJ09614.1 - 9.3e-06 25.2 0.1 1.9e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 R3H domain SNF2_N PF00176.18 OAJ09623.1 - 1.8e-65 220.7 0.0 3.6e-65 219.7 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Rad54_N PF08658.5 OAJ09623.1 - 1.8e-40 138.7 0.0 3e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 OAJ09623.1 - 1.4e-10 40.9 0.0 3.6e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 OAJ09623.1 - 5.3e-06 25.4 0.0 2.3e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 OAJ09623.1 - 0.044 13.6 0.0 0.71 9.6 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ERAP1_C PF11838.3 OAJ09624.1 - 2e-62 211.2 0.1 2.9e-62 210.7 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.15 OAJ09624.1 - 5e-08 32.4 0.0 8.8e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 OAJ09624.1 - 0.033 14.2 0.0 0.087 12.8 0.0 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily Ribosomal_L5_C PF00673.16 OAJ09633.1 - 8e-21 73.5 0.0 1.3e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 OAJ09633.1 - 2.2e-19 68.9 0.0 4.5e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Prefoldin_2 PF01920.15 OAJ09634.1 - 2.8e-22 78.4 14.3 3.5e-22 78.1 9.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit NPV_P10 PF05531.7 OAJ09634.1 - 8.2e-05 22.7 5.6 0.057 13.6 0.1 2.1 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein Lzipper-MIP1 PF14389.1 OAJ09634.1 - 0.0016 18.4 7.7 0.002 18.2 1.5 2.3 2 1 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 Uds1 PF15456.1 OAJ09634.1 - 0.012 15.5 7.7 0.015 15.2 4.9 1.6 1 1 0 1 1 1 0 Up-regulated During Septation Prefoldin_3 PF13758.1 OAJ09634.1 - 0.015 15.0 6.5 0.018 14.7 4.2 1.4 1 1 0 1 1 1 0 Prefoldin subunit DUF3166 PF11365.3 OAJ09634.1 - 0.024 15.1 3.2 4.5 7.7 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) MAP65_ASE1 PF03999.7 OAJ09634.1 - 0.026 13.1 4.6 0.031 12.8 3.2 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DASH_Dam1 PF08653.5 OAJ09634.1 - 0.049 13.3 2.0 4.7 7.0 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 BRE1 PF08647.6 OAJ09634.1 - 0.053 13.4 1.7 0.053 13.4 1.2 2.3 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase OmdA PF13376.1 OAJ09634.1 - 0.056 13.1 0.4 0.16 11.6 0.1 1.9 2 0 0 2 2 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Spore_YpjB PF09577.5 OAJ09634.1 - 0.071 12.6 3.9 0.088 12.3 2.7 1.1 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) DUF724 PF05266.9 OAJ09634.1 - 0.077 12.6 10.1 0.11 12.1 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FlxA PF14282.1 OAJ09634.1 - 0.13 12.1 14.4 0.22 11.4 1.0 2.2 2 0 0 2 2 2 0 FlxA-like protein AAA_27 PF13514.1 OAJ09634.1 - 0.14 9.8 11.9 0.15 9.6 8.3 1.0 1 0 0 1 1 1 0 AAA domain Fucose_iso_N2 PF07882.7 OAJ09634.1 - 0.14 11.7 2.0 0.15 11.6 1.4 1.1 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Vac_Fusion PF02346.11 OAJ09634.1 - 0.18 11.2 2.1 11 5.5 0.3 2.3 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Mnd1 PF03962.10 OAJ09634.1 - 0.18 11.4 13.4 0.4 10.3 3.9 2.0 1 1 1 2 2 2 0 Mnd1 family DUF2205 PF10224.4 OAJ09634.1 - 0.18 11.3 11.4 0.06 12.9 1.0 2.2 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Atg14 PF10186.4 OAJ09634.1 - 0.2 10.5 12.3 0.52 9.2 8.5 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 OAJ09634.1 - 0.21 11.4 14.0 0.14 12.0 3.2 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_MT_bd PF06657.8 OAJ09634.1 - 0.26 11.2 8.5 0.3 11.0 1.2 2.7 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 KxDL PF10241.4 OAJ09634.1 - 0.31 10.9 5.2 0.6 10.0 0.1 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein Nup54 PF13874.1 OAJ09634.1 - 0.32 10.6 11.5 0.75 9.4 2.2 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Macoilin PF09726.4 OAJ09634.1 - 0.33 9.1 13.3 0.38 8.9 9.2 1.0 1 0 0 1 1 1 0 Transmembrane protein PHTB1_C PF14728.1 OAJ09634.1 - 0.4 9.4 4.5 0.53 9.0 3.1 1.3 1 1 0 1 1 1 0 PTHB1 C-terminus Spc7 PF08317.6 OAJ09634.1 - 0.41 9.2 14.1 0.56 8.8 9.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein KMP11 PF03037.11 OAJ09634.1 - 0.44 11.1 4.7 0.8 10.3 2.4 1.9 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 APG6 PF04111.7 OAJ09634.1 - 0.45 9.5 15.0 0.16 11.0 5.6 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 LPP PF04728.8 OAJ09634.1 - 0.53 10.1 5.2 3.4 7.5 1.0 2.7 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Occludin_ELL PF07303.8 OAJ09634.1 - 0.59 10.9 7.9 5.2 7.8 1.7 2.2 1 1 1 2 2 2 0 Occludin homology domain HrpB7 PF09486.5 OAJ09634.1 - 0.72 9.7 8.5 6.6 6.6 0.4 2.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) LLC1 PF14945.1 OAJ09634.1 - 0.72 10.1 3.8 0.36 11.1 0.6 1.8 1 1 1 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Laminin_II PF06009.7 OAJ09634.1 - 0.73 9.5 11.2 0.26 11.0 1.0 2.1 1 1 0 2 2 2 0 Laminin Domain II SlyX PF04102.7 OAJ09634.1 - 0.76 10.1 11.1 0.085 13.2 0.9 2.5 2 1 0 2 2 2 0 SlyX Baculo_PEP_C PF04513.7 OAJ09634.1 - 0.77 9.5 6.7 1.8 8.4 0.4 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliD_C PF07195.7 OAJ09634.1 - 0.85 8.8 10.4 6.1 6.0 7.2 1.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus IncA PF04156.9 OAJ09634.1 - 0.94 9.0 16.2 5.7 6.4 11.3 1.9 1 1 0 1 1 1 0 IncA protein Med4 PF10018.4 OAJ09634.1 - 1.1 8.6 8.5 0.34 10.2 0.1 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF1664 PF07889.7 OAJ09634.1 - 1.3 8.8 9.2 1.6 8.5 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Sas10_Utp3 PF04000.10 OAJ09634.1 - 1.5 9.0 5.6 5.6 7.2 0.1 2.4 2 1 0 2 2 2 0 Sas10/Utp3/C1D family Fib_alpha PF08702.5 OAJ09634.1 - 1.8 8.6 11.8 15 5.7 7.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GrpE PF01025.14 OAJ09634.1 - 2.1 7.8 12.3 2.7 7.5 1.7 2.1 2 0 0 2 2 2 0 GrpE Phlebovirus_NSM PF07246.6 OAJ09634.1 - 2.2 7.3 7.0 3 6.9 4.9 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Peptidase_S46 PF10459.4 OAJ09634.1 - 2.3 6.5 9.0 2.8 6.2 6.2 1.0 1 0 0 1 1 1 0 Peptidase S46 Mto2_bdg PF12808.2 OAJ09634.1 - 2.4 8.3 10.6 11 6.2 0.3 3.4 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region AATF-Che1 PF13339.1 OAJ09634.1 - 2.5 8.2 10.1 12 6.1 7.0 1.9 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Med28 PF11594.3 OAJ09634.1 - 2.6 8.3 9.0 2.7 8.2 2.1 2.0 1 1 1 2 2 2 0 Mediator complex subunit 28 Dict-STAT-coil PF09267.5 OAJ09634.1 - 2.7 8.2 8.0 2 8.6 1.9 2.2 1 1 0 2 2 2 0 Dictyostelium STAT, coiled coil Seryl_tRNA_N PF02403.17 OAJ09634.1 - 2.7 8.0 13.8 48 4.0 9.5 2.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.6 OAJ09634.1 - 2.8 7.6 14.6 11 5.8 10.1 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.3 OAJ09634.1 - 2.9 7.6 14.9 4.5 7.0 2.6 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding SKIP_SNW PF02731.10 OAJ09634.1 - 3.3 7.1 9.0 2.7 7.4 1.4 2.1 2 0 0 2 2 2 0 SKIP/SNW domain Allexi_40kDa PF05549.6 OAJ09634.1 - 3.4 6.8 6.5 1.9 7.6 1.6 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF3106 PF11304.3 OAJ09634.1 - 3.4 8.1 8.4 1 9.8 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) bZIP_1 PF00170.16 OAJ09634.1 - 3.4 7.6 11.1 8.3 6.4 0.8 3.0 2 1 1 3 3 3 0 bZIP transcription factor ORF6C PF10552.4 OAJ09634.1 - 3.4 7.4 8.4 1.1 8.9 2.0 2.3 1 1 1 2 2 2 0 ORF6C domain CENP-Q PF13094.1 OAJ09634.1 - 4.6 7.2 16.5 3.5 7.6 1.8 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc24 PF08286.6 OAJ09634.1 - 5.2 6.7 15.8 12 5.5 2.9 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF948 PF06103.6 OAJ09634.1 - 5.4 6.9 6.8 2.1 8.2 0.8 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) YgaB PF14182.1 OAJ09634.1 - 5.4 7.3 13.3 0.44 10.8 2.4 2.4 2 1 0 2 2 2 0 YgaB-like protein Tropomyosin_1 PF12718.2 OAJ09634.1 - 5.5 6.8 18.3 99 2.7 12.7 2.3 1 1 0 1 1 1 0 Tropomyosin like DUF607 PF04678.8 OAJ09634.1 - 5.5 6.8 7.2 4.4 7.1 2.0 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Prefoldin PF02996.12 OAJ09634.1 - 5.5 6.6 14.9 0.87 9.2 3.1 2.7 2 1 1 3 3 3 0 Prefoldin subunit Rootletin PF15035.1 OAJ09634.1 - 5.7 6.8 14.1 3.4 7.6 5.9 2.5 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion ADIP PF11559.3 OAJ09634.1 - 6.3 6.6 16.4 4.6 7.1 2.7 2.2 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 OAJ09634.1 - 6.7 7.1 12.9 10 6.5 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 OAJ09634.1 - 6.8 5.0 14.3 12 4.2 9.9 1.4 1 1 0 1 1 1 0 AAA domain Kinetocho_Slk19 PF12709.2 OAJ09634.1 - 8.2 6.5 13.8 5.2 7.2 1.5 3.1 2 2 2 4 4 3 0 Central kinetochore-associated DUF641 PF04859.7 OAJ09634.1 - 8.5 6.1 13.0 2.8 7.7 3.0 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TPR_MLP1_2 PF07926.7 OAJ09634.1 - 9 6.0 17.5 1.6e+02 1.9 11.0 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 OAJ09634.1 - 9.7 5.6 17.1 21 4.5 3.8 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 ALS_ss_C PF10369.4 OAJ09635.1 - 1.2e-20 72.9 0.0 3.1e-19 68.4 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 OAJ09635.1 - 2.5e-12 45.9 0.1 5e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 OAJ09635.1 - 7.4e-09 35.2 0.1 2.6e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 ACT domain Macoilin PF09726.4 OAJ09635.1 - 3.8 5.6 12.0 6.1 5.0 8.3 1.2 1 0 0 1 1 1 0 Transmembrane protein Oxygenase-NA PF09859.4 OAJ09639.1 - 0.028 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA RVT_1 PF00078.22 OAJ09640.1 - 8.9e-16 57.8 0.0 1.9e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_14 PF13428.1 OAJ09640.1 - 0.073 13.7 2.1 1.3 9.8 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Hap4_Hap_bind PF10297.4 OAJ09640.1 - 0.74 9.7 3.9 2 8.3 0.9 2.6 2 0 0 2 2 2 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 Formyl_trans_N PF00551.14 OAJ09645.1 - 8.7e-28 97.0 0.0 2.3e-27 95.6 0.0 1.8 1 1 0 1 1 1 1 Formyl transferase CAP PF00188.21 OAJ09646.1 - 1.1e-19 71.0 1.2 1.7e-19 70.5 0.9 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Med3 PF11593.3 OAJ09646.1 - 0.0041 16.4 13.2 0.0047 16.2 9.2 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Tyrosinase PF00264.15 OAJ09646.1 - 0.1 12.7 0.4 0.13 12.3 0.3 1.3 1 0 0 1 1 1 0 Common central domain of tyrosinase TFIIA PF03153.8 OAJ09646.1 - 1.8 8.3 3.5 2.5 7.9 2.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GMC_oxred_N PF00732.14 OAJ09651.1 - 7.4e-48 163.2 0.0 1e-47 162.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ09651.1 - 5.2e-37 127.3 0.0 9e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAJ09651.1 - 2.2e-06 26.8 0.2 0.00052 19.0 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ09651.1 - 0.00018 20.4 0.3 0.0055 15.6 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 OAJ09651.1 - 0.00026 20.9 0.1 0.0007 19.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAJ09651.1 - 0.00043 19.3 0.1 0.00063 18.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAJ09651.1 - 0.002 18.2 0.2 0.51 10.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ09651.1 - 0.014 15.3 0.4 0.065 13.1 0.1 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ09651.1 - 0.061 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 OAJ09651.1 - 0.097 12.4 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding EntA_Immun PF08951.5 OAJ09652.1 - 0.042 14.0 0.1 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 Enterocin A Immunity Peptidase_S10 PF00450.17 OAJ09659.1 - 1.6e-73 248.2 0.0 2.1e-73 247.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 OAJ09659.1 - 0.016 15.1 0.0 0.054 13.3 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family MPC PF03650.8 OAJ09664.1 - 9.2e-39 132.0 0.2 1.1e-38 131.8 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Pex19 PF04614.7 OAJ09665.1 - 4.7e-55 186.8 1.0 4.7e-55 186.8 0.7 1.7 1 1 1 2 2 2 1 Pex19 protein family DUF1018 PF06252.7 OAJ09665.1 - 0.055 13.9 0.0 21 5.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1018) Sigma70_ner PF04546.8 OAJ09665.1 - 0.85 9.1 11.2 0.96 9.0 4.0 2.4 3 0 0 3 3 3 0 Sigma-70, non-essential region ALAD PF00490.16 OAJ09666.1 - 1.3e-116 389.0 0.0 1.4e-116 388.9 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Retrotrans_gag PF03732.12 OAJ09671.1 - 0.03 14.3 0.0 0.087 12.9 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.22 OAJ09672.1 - 3.7e-17 62.4 0.0 7.2e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09672.1 - 3e-16 59.6 0.0 5.5e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ09672.1 - 0.02 15.4 0.0 0.092 13.2 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease FTR1 PF03239.9 OAJ09677.1 - 0.0055 15.6 0.4 0.0066 15.4 0.2 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3262 PF11660.3 OAJ09677.1 - 0.47 10.5 3.6 0.82 9.7 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3262) UCR_TM PF02921.9 OAJ09678.1 - 1.2e-19 70.2 2.6 2.8e-19 69.0 1.8 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 OAJ09678.1 - 1.2e-16 60.0 0.1 2.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pex2_Pex12 PF04757.9 OAJ09679.1 - 1.2e-24 87.0 0.3 1.3e-24 86.8 0.2 1.0 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region CDRN PF05174.7 OAJ09679.1 - 0.12 11.8 1.0 2.8 7.4 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich D. radiodurans N terminus Striatin PF08232.7 OAJ09686.1 - 0.98 9.7 16.1 0.012 15.9 3.6 2.6 2 0 0 2 2 2 0 Striatin family Gti1_Pac2 PF09729.4 OAJ09697.1 - 1.6e-33 115.9 6.1 3.4e-29 101.8 0.8 6.0 4 2 1 5 5 5 2 Gti1/Pac2 family RVT_1 PF00078.22 OAJ09704.1 - 9.3e-19 67.6 0.0 1.7e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09704.1 - 3.7e-12 46.4 0.0 1.2e-11 44.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.15 OAJ09704.1 - 0.00031 20.6 0.0 0.00064 19.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAJ09704.1 - 0.028 14.9 0.0 0.08 13.4 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Myb_DNA-binding PF00249.26 OAJ09714.1 - 8.1e-11 41.8 0.0 1.3e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain AATase PF07247.7 OAJ09719.1 - 0.026 13.1 0.0 0.058 11.9 0.0 1.4 1 1 0 1 1 1 0 Alcohol acetyltransferase Tetraspannin PF00335.15 OAJ09720.1 - 0.0029 16.9 10.3 0.0029 16.9 7.2 1.6 1 1 0 1 1 1 1 Tetraspanin family ApoO PF09769.4 OAJ09720.1 - 0.012 15.2 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 Apolipoprotein O TMEM51 PF15345.1 OAJ09720.1 - 0.017 14.8 0.4 0.47 10.0 0.3 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 DUF3481 PF11980.3 OAJ09720.1 - 0.22 11.3 0.1 0.22 11.3 0.0 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF3481) Cyto_ox_2 PF02322.10 OAJ09720.1 - 2.3 7.3 18.0 3.3 6.8 12.5 1.2 1 0 0 1 1 1 0 Cytochrome oxidase subunit II DUF3302 PF11742.3 OAJ09720.1 - 2.9 7.7 10.2 3.2 7.6 1.6 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3302) EphA2_TM PF14575.1 OAJ09720.1 - 7.1 7.1 0.0 7.1 7.1 0.0 3.4 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF2157 PF09925.4 OAJ09720.1 - 9.3 5.8 17.3 12 5.4 0.5 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) VWA_2 PF13519.1 OAJ09721.1 - 4.2e-10 39.9 0.2 4.2e-10 39.9 0.1 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 OAJ09721.1 - 0.00012 21.9 0.4 0.063 12.9 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain BNR_assoc_N PF14873.1 OAJ09721.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of BNR-repeat neuraminidase ANAPC15 PF15243.1 OAJ09729.1 - 0.19 11.8 4.7 0.36 10.9 3.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Nop14 PF04147.7 OAJ09729.1 - 0.42 8.4 4.4 0.57 8.0 3.1 1.1 1 0 0 1 1 1 0 Nop14-like family COPI_C PF06957.6 OAJ09729.1 - 1.9 6.9 5.3 3.2 6.1 3.7 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Sigma70_ner PF04546.8 OAJ09729.1 - 3.8 7.0 4.9 8.6 5.9 3.4 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM72 PF14976.1 OAJ09730.1 - 0.034 13.9 0.9 0.067 13.0 0.6 1.4 1 0 0 1 1 1 0 FAM72 protein Ribonucleas_3_3 PF14622.1 OAJ09735.1 - 1.5e-07 31.3 0.0 0.026 14.4 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 OAJ09735.1 - 1.6e-05 25.3 0.0 4.7e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.20 OAJ09735.1 - 0.091 13.3 0.0 0.091 13.3 0.0 2.0 2 0 0 2 2 2 0 Double-stranded RNA binding motif WD40 PF00400.27 OAJ09736.1 - 7.4e-43 142.9 13.1 2.4e-12 46.1 0.3 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 OAJ09736.1 - 0.0017 17.4 0.4 0.016 14.2 0.0 2.6 4 0 0 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.3 OAJ09736.1 - 0.013 13.6 4.4 0.37 8.8 0.0 3.7 3 2 1 4 4 4 0 Nucleoporin Nup120/160 DUF605 PF04652.11 OAJ09736.1 - 1.2 8.4 12.6 1.6 8.0 8.8 1.1 1 0 0 1 1 1 0 Vta1 like IPPT PF01715.12 OAJ09737.1 - 1.9e-10 40.2 0.0 2.4e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 OAJ09737.1 - 5.8e-05 23.9 0.0 6.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ09737.1 - 0.0031 17.2 0.0 0.0072 16.0 0.0 1.6 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 OAJ09737.1 - 0.0037 17.2 0.1 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ09737.1 - 0.0043 17.1 0.0 0.0053 16.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ09737.1 - 0.0061 16.8 0.0 0.0061 16.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 OAJ09737.1 - 0.0061 15.8 0.0 0.0098 15.1 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein IPT PF01745.11 OAJ09737.1 - 0.013 14.6 0.4 0.19 10.8 0.2 2.0 1 1 0 1 1 1 0 Isopentenyl transferase AAA_25 PF13481.1 OAJ09737.1 - 0.018 14.4 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 OAJ09737.1 - 0.026 14.4 0.1 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 OAJ09737.1 - 0.028 14.3 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 OAJ09737.1 - 0.08 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein MobB PF03205.9 OAJ09737.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 OAJ09737.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Ribosomal_L35Ae PF01247.13 OAJ09738.1 - 2.8e-39 132.8 0.8 3.1e-39 132.6 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 OAJ09738.1 - 0.086 12.7 0.1 12 5.9 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain SWIB PF02201.13 OAJ09741.1 - 5.3e-28 96.5 0.1 8.2e-28 95.9 0.1 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 OAJ09741.1 - 7.2e-07 28.8 1.6 5.6e-05 22.8 0.4 2.9 3 0 0 3 3 3 1 DEK C terminal domain TFIIF_alpha PF05793.7 OAJ09741.1 - 3.6 5.8 11.1 0.26 9.6 3.0 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LSM PF01423.17 OAJ09742.1 - 7.1e-16 57.5 0.1 9.8e-16 57.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain MRJP PF03022.11 OAJ09742.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.0 1 0 0 1 1 1 0 Major royal jelly protein GCV_T PF01571.16 OAJ09747.1 - 2.3e-14 53.2 0.0 1.8e-13 50.3 0.0 2.0 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 OAJ09747.1 - 0.00092 19.1 0.0 0.0026 17.7 0.0 1.9 1 1 1 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain eIF2A PF08662.6 OAJ09748.1 - 4.2e-41 140.8 0.7 1.9e-36 125.6 0.1 4.4 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 OAJ09748.1 - 6.6e-06 25.6 0.1 1.5e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ09748.1 - 8.6e-06 25.6 0.1 2.3e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ09748.1 - 7.2e-05 22.5 0.1 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 OAJ09748.1 - 0.00058 19.6 7.1 0.2 11.6 0.0 5.4 6 0 0 6 6 6 1 WD domain, G-beta repeat DPPIV_N PF00930.16 OAJ09748.1 - 0.031 12.8 0.1 2.4 6.6 0.0 3.2 3 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Phage_integrase PF00589.17 OAJ09754.1 - 3e-06 27.0 0.0 4.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family zf-CCHC PF00098.18 OAJ09762.1 - 1.3e-06 27.9 2.0 1.3e-06 27.9 1.4 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ09762.1 - 0.00055 19.3 0.4 0.0011 18.4 0.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 OAJ09762.1 - 0.03 13.8 0.5 0.056 12.9 0.3 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.1 OAJ09762.1 - 0.053 13.1 1.4 0.09 12.4 1.0 1.3 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.21 OAJ09763.1 - 2.2e-19 69.6 0.0 4e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ09763.1 - 6.2e-07 28.9 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ09763.1 - 0.0011 18.4 0.1 0.031 13.8 0.0 2.7 3 0 0 3 3 3 1 Integrase core domain Flt3_lig PF02947.9 OAJ09763.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 flt3 ligand RVT_2 PF07727.9 OAJ09764.1 - 7.1e-55 185.6 0.0 9.5e-55 185.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAJ09764.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_3 PF12776.2 OAJ09770.1 - 0.0056 17.2 0.1 0.012 16.1 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Pox_T4_N PF04491.7 OAJ09770.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus Retrotrans_gag PF03732.12 OAJ09771.1 - 0.0061 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF2205 PF10224.4 OAJ09771.1 - 0.07 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Golgin_A5 PF09787.4 OAJ09771.1 - 3.2 6.1 7.6 4.4 5.7 5.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 zf-C4H2 PF10146.4 OAJ09771.1 - 7.3 6.5 6.7 0.4 10.6 0.5 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein DDE_Tnp_4 PF13359.1 OAJ09772.1 - 3.6e-28 98.1 0.0 4.6e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ09772.1 - 3.7e-06 26.4 0.1 7.6e-06 25.4 0.0 1.5 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.16 OAJ09772.1 - 1.1e-05 25.0 0.0 2.7e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.1 OAJ09772.1 - 0.01 15.9 0.2 0.022 14.9 0.1 1.4 1 0 0 1 1 1 0 Transposase DDE domain SPX PF03105.14 OAJ09776.1 - 0.00026 20.8 2.0 0.00029 20.7 1.4 1.1 1 0 0 1 1 1 1 SPX domain HOOK PF05622.7 OAJ09776.1 - 0.0027 15.6 4.2 0.0029 15.5 2.9 1.0 1 0 0 1 1 1 1 HOOK protein Herpes_UL25 PF01499.11 OAJ09776.1 - 0.0052 15.1 2.3 0.0054 15.1 1.6 1.0 1 0 0 1 1 1 1 Herpesvirus UL25 family WD40_alt PF14077.1 OAJ09776.1 - 0.017 14.7 0.5 0.037 13.6 0.4 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF4482 PF14818.1 OAJ09776.1 - 0.022 15.4 1.7 0.038 14.6 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) DUF607 PF04678.8 OAJ09776.1 - 0.037 13.9 0.9 0.04 13.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 HAUS-augmin3 PF14932.1 OAJ09776.1 - 0.16 11.1 4.0 0.19 10.8 2.8 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 V_ATPase_I PF01496.14 OAJ09776.1 - 0.18 9.6 1.2 0.17 9.6 0.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 OAJ09776.1 - 0.34 9.9 2.9 0.37 9.7 2.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 T2SM PF04612.7 OAJ09776.1 - 0.45 10.2 4.6 3.3 7.4 1.3 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M IncA PF04156.9 OAJ09776.1 - 0.69 9.4 3.7 0.78 9.2 2.6 1.1 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 OAJ09776.1 - 1.7 7.5 4.5 2.3 7.1 3.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4337 PF14235.1 OAJ09776.1 - 7.2 6.4 7.7 8.7 6.1 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) TAF8_C PF10406.4 OAJ09777.1 - 0.062 13.3 1.0 0.4 10.7 0.1 2.2 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term DUF4207 PF13904.1 OAJ09781.1 - 0.034 13.5 4.8 0.051 12.9 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DUF4398 PF14346.1 OAJ09782.1 - 0.046 13.7 1.2 0.088 12.8 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) DUF3596 PF12167.3 OAJ09783.1 - 0.014 14.9 0.1 0.027 14.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) GBA2_N PF12215.3 OAJ09795.1 - 0.0092 15.1 0.0 0.02 14.0 0.0 1.6 2 0 0 2 2 2 1 beta-Glucocerebrosidase 2 N terminal Gag_spuma PF03276.9 OAJ09797.1 - 0.13 10.5 0.0 0.19 10.0 0.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein UQ_con PF00179.21 OAJ09801.1 - 9.9e-17 60.6 0.0 1.1e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 OAJ09801.1 - 0.004 17.0 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 OAJ09801.1 - 0.12 12.0 0.1 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 UEV domain Ribonuc_P_40 PF08584.6 OAJ09802.1 - 1.6e-35 122.5 0.0 3.8e-21 75.3 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit Myc_N PF01056.13 OAJ09802.1 - 0.6 9.2 5.8 1 8.4 4.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.9 OAJ09802.1 - 1.3 6.9 12.0 2 6.3 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 OAJ09802.1 - 2.2 7.9 14.2 0.17 11.5 6.3 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 OAJ09802.1 - 2.2 6.0 9.9 3.3 5.5 6.9 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C2H2_4 PF13894.1 OAJ09803.1 - 0.008 16.4 8.9 0.93 9.9 0.0 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger SSP160 PF06933.6 OAJ09803.1 - 0.17 9.8 4.5 0.19 9.6 3.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-C2H2 PF00096.21 OAJ09803.1 - 0.33 11.3 13.7 2.3 8.7 0.6 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Ribosomal_S3Ae PF01015.13 OAJ09810.1 - 9.3e-80 266.5 0.9 1.1e-79 266.3 0.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 OAJ09810.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region SET PF00856.23 OAJ09811.1 - 8e-05 22.9 0.0 0.02 15.1 0.0 2.4 2 0 0 2 2 2 2 SET domain SAF PF08666.7 OAJ09811.1 - 0.035 14.5 0.0 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 SAF domain Cation_ATPase_C PF00689.16 OAJ09815.1 - 2.8e-36 124.7 2.1 4.2e-36 124.1 1.5 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ09815.1 - 2.7e-27 96.6 0.0 3.6e-26 92.9 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ09815.1 - 7.8e-15 54.6 0.0 1.4e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 OAJ09815.1 - 1.2e-12 48.4 0.2 2.9e-12 47.1 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2556 PF10831.3 OAJ09815.1 - 0.016 14.8 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2556) Hydrolase_3 PF08282.7 OAJ09815.1 - 0.083 12.4 0.2 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase An_peroxidase PF03098.10 OAJ09816.1 - 6.3e-74 249.2 0.0 2.4e-71 240.7 0.0 2.3 1 1 0 1 1 1 1 Animal haem peroxidase RRM_6 PF14259.1 OAJ09823.1 - 0.00092 19.1 0.0 0.1 12.5 0.0 3.3 3 1 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) OrfB_Zn_ribbon PF07282.6 OAJ09824.1 - 0.00086 18.9 1.0 0.038 13.6 0.0 2.6 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Acetyltransf_10 PF13673.1 OAJ09824.1 - 0.018 15.1 0.0 0.075 13.1 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain HEAT PF02985.17 OAJ09830.1 - 2.3e-25 86.3 7.8 9.7e-05 22.1 0.0 11.1 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.1 OAJ09830.1 - 1.1e-19 70.3 6.0 1.4e-07 31.7 0.0 8.7 8 0 0 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.1 OAJ09830.1 - 1.5e-18 66.8 13.8 0.00042 20.5 0.0 6.9 3 2 5 8 8 8 6 HEAT repeats IBN_N PF03810.14 OAJ09830.1 - 6.6e-12 45.1 2.9 1.1e-09 38.0 0.1 3.8 3 1 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 OAJ09830.1 - 0.00047 20.0 0.7 0.083 12.8 0.2 3.7 2 1 0 2 2 2 1 Exportin 1-like protein Arm PF00514.18 OAJ09830.1 - 0.00051 19.7 11.4 0.028 14.2 0.1 5.5 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 OAJ09830.1 - 0.00052 20.3 0.2 0.55 10.6 0.1 4.9 5 1 2 7 7 7 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 OAJ09830.1 - 0.00065 18.1 2.1 1.1 7.5 0.1 3.5 2 2 1 3 3 3 2 Adaptin N terminal region TIP120 PF08623.5 OAJ09830.1 - 0.00082 18.9 0.2 4.4 6.8 0.0 4.1 3 1 1 4 4 4 1 TATA-binding protein interacting (TIP20) MMS19_N PF14500.1 OAJ09830.1 - 0.0021 17.3 0.1 0.018 14.2 0.1 2.2 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II CLASP_N PF12348.3 OAJ09830.1 - 0.028 13.8 0.3 3.2 7.0 0.0 3.7 3 1 1 4 4 4 0 CLASP N terminal Pex14_N PF04695.8 OAJ09831.1 - 1.2e-31 109.5 0.0 1.2e-31 109.5 0.0 3.8 2 1 0 3 3 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 OAJ09831.1 - 1.9e-06 27.6 3.5 3.4e-06 26.7 2.4 1.4 1 0 0 1 1 1 1 IncA protein NPV_P10 PF05531.7 OAJ09831.1 - 0.0003 20.9 5.7 0.027 14.6 0.3 3.0 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 OAJ09831.1 - 0.0012 18.5 2.9 0.0012 18.5 2.0 2.4 2 1 1 3 3 2 2 Laminin Domain II Atg14 PF10186.4 OAJ09831.1 - 0.0034 16.3 0.5 0.0049 15.8 0.3 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 OAJ09831.1 - 0.0042 15.6 1.9 0.0058 15.1 1.3 1.1 1 0 0 1 1 1 1 AAA domain MAD PF05557.8 OAJ09831.1 - 0.0055 14.8 4.1 0.01 13.9 2.9 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein EzrA PF06160.7 OAJ09831.1 - 0.0096 14.1 3.4 0.015 13.5 2.4 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA OmpH PF03938.9 OAJ09831.1 - 0.011 15.7 7.2 0.02 14.8 5.0 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PilJ PF13675.1 OAJ09831.1 - 0.011 16.0 7.5 0.053 13.8 3.2 2.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Baculo_PEP_C PF04513.7 OAJ09831.1 - 0.021 14.6 0.7 0.074 12.8 0.5 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 OAJ09831.1 - 0.025 11.9 10.0 0.033 11.5 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_I PF06008.9 OAJ09831.1 - 0.026 13.8 8.1 0.044 13.0 5.6 1.3 1 0 0 1 1 1 0 Laminin Domain I TBPIP PF07106.8 OAJ09831.1 - 0.032 13.7 4.9 0.033 13.7 1.2 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Sipho_Gp157 PF05565.6 OAJ09831.1 - 0.041 13.4 4.0 0.066 12.7 2.8 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 IFT57 PF10498.4 OAJ09831.1 - 0.059 12.1 6.4 0.019 13.6 1.9 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1395 PF07160.7 OAJ09831.1 - 0.073 12.5 4.8 0.13 11.7 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Spc7 PF08317.6 OAJ09831.1 - 0.075 11.6 4.9 0.17 10.4 3.4 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 OAJ09831.1 - 0.082 11.9 8.6 0.12 11.4 5.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2968 PF11180.3 OAJ09831.1 - 0.098 12.0 11.8 0.34 10.2 8.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) HALZ PF02183.13 OAJ09831.1 - 0.22 11.2 7.9 0.41 10.4 0.1 3.2 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF342 PF03961.8 OAJ09831.1 - 0.29 9.5 3.3 0.43 8.9 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2317 PF10079.4 OAJ09831.1 - 0.32 9.5 4.2 0.47 9.0 2.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Rep_4 PF05797.6 OAJ09831.1 - 0.35 9.5 2.8 0.48 9.0 2.0 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) FlgN PF05130.7 OAJ09831.1 - 0.37 11.0 10.9 0.63 10.2 7.6 1.3 1 0 0 1 1 1 0 FlgN protein Nup88 PF10168.4 OAJ09831.1 - 0.43 8.3 4.2 0.59 7.9 2.9 1.1 1 0 0 1 1 1 0 Nuclear pore component Occludin_ELL PF07303.8 OAJ09831.1 - 0.5 11.1 5.1 2.1 9.1 1.8 2.3 1 1 1 2 2 2 0 Occludin homology domain DUF1664 PF07889.7 OAJ09831.1 - 0.58 9.9 8.1 0.71 9.6 2.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMPIT PF07851.8 OAJ09831.1 - 0.87 8.5 3.5 1.2 8.1 2.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.1 OAJ09831.1 - 0.98 8.3 9.0 0.07 12.0 2.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.5 OAJ09831.1 - 1 9.5 3.7 1.9 8.6 1.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin PF00804.20 OAJ09831.1 - 1.1 9.4 8.5 36 4.5 5.9 2.4 1 1 0 1 1 1 0 Syntaxin DUF2408 PF10303.4 OAJ09831.1 - 1.5 8.9 5.0 11 6.1 3.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Spectrin PF00435.16 OAJ09831.1 - 1.6 9.0 7.6 0.66 10.2 1.7 2.2 1 1 1 2 2 2 0 Spectrin repeat BLOC1_2 PF10046.4 OAJ09831.1 - 1.7 8.8 6.3 3 8.0 1.3 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG2 PF06148.6 OAJ09831.1 - 1.8 8.4 6.5 25 4.7 4.5 2.2 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 ADIP PF11559.3 OAJ09831.1 - 1.9 8.3 9.2 0.5 10.2 2.9 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 OAJ09831.1 - 2.5 5.8 3.7 3.6 5.3 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 OAJ09831.1 - 3.4 8.0 7.4 5.9 7.2 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 OAJ09831.1 - 3.6 7.2 9.6 8.9 5.9 6.7 1.6 1 1 0 1 1 1 0 Mnd1 family V-SNARE PF05008.10 OAJ09831.1 - 5 7.3 9.8 7.6 6.7 5.3 2.2 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Med9 PF07544.8 OAJ09831.1 - 5.8 6.7 8.9 8.4 6.2 0.2 3.0 2 1 1 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.15 OAJ09831.1 - 7.1 6.4 11.2 12 5.6 4.1 2.9 1 1 2 3 3 3 0 Prefoldin subunit Bax1-I PF01027.15 OAJ09837.1 - 2e-34 119.0 7.8 3.6e-34 118.1 5.4 1.4 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CitT PF12431.3 OAJ09838.1 - 0.00049 20.0 0.2 5.2 7.2 0.0 4.1 3 0 0 3 3 3 2 Transcriptional regulator AAA_2 PF07724.9 OAJ09845.1 - 7.9e-46 156.0 0.0 7.1e-44 149.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 OAJ09845.1 - 1e-23 83.9 0.0 2.7e-12 47.0 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 OAJ09845.1 - 1e-21 76.5 0.1 4.5e-21 74.5 0.0 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 OAJ09845.1 - 5.6e-14 52.0 0.0 1.1e-07 31.6 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 OAJ09845.1 - 1.3e-12 47.4 3.0 3.5e-06 26.8 0.5 3.8 3 0 0 3 3 3 2 Clp amino terminal domain AAA_16 PF13191.1 OAJ09845.1 - 7.2e-11 42.4 0.1 2.1e-07 31.0 0.0 5.8 5 3 1 7 7 6 2 AAA ATPase domain AAA_22 PF13401.1 OAJ09845.1 - 2.7e-10 40.4 1.5 0.002 18.2 0.0 4.6 3 2 1 4 4 3 2 AAA domain IstB_IS21 PF01695.12 OAJ09845.1 - 6.2e-08 32.2 0.0 0.016 14.6 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_17 PF13207.1 OAJ09845.1 - 4.5e-07 30.7 4.2 0.0093 16.7 0.0 4.0 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.1 OAJ09845.1 - 2e-06 28.1 0.5 0.16 12.2 0.0 3.4 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 OAJ09845.1 - 4e-06 26.4 0.0 0.0025 17.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 OAJ09845.1 - 1.5e-05 24.8 0.1 0.025 14.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 OAJ09845.1 - 6.5e-05 23.0 0.0 0.22 11.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.8 OAJ09845.1 - 7.9e-05 21.7 0.0 0.45 9.3 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF815) AAA_19 PF13245.1 OAJ09845.1 - 8.7e-05 22.2 0.1 0.089 12.5 0.1 3.1 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 OAJ09845.1 - 0.00011 21.3 0.0 0.023 13.7 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin Arch_ATPase PF01637.13 OAJ09845.1 - 0.00022 20.9 8.3 0.038 13.6 0.0 5.1 4 2 1 6 6 6 1 Archaeal ATPase DUF258 PF03193.11 OAJ09845.1 - 0.00023 20.4 0.0 0.53 9.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 OAJ09845.1 - 0.00029 20.5 0.0 0.34 10.6 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 OAJ09845.1 - 0.00031 20.4 0.0 0.17 11.5 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.1 OAJ09845.1 - 0.00071 19.2 0.0 0.65 9.5 0.0 3.0 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.16 OAJ09845.1 - 0.00075 18.7 0.0 0.18 10.9 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 OAJ09845.1 - 0.00093 19.1 2.7 0.78 9.6 0.0 3.6 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 OAJ09845.1 - 0.0013 17.8 0.0 0.21 10.5 0.0 2.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 OAJ09845.1 - 0.0015 17.9 1.6 1.5 8.1 0.0 4.2 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.22 OAJ09845.1 - 0.0034 17.6 0.4 1.6 9.0 0.0 3.4 3 0 0 3 3 3 1 ABC transporter NTPase_1 PF03266.10 OAJ09845.1 - 0.0035 17.0 0.0 2.2 7.9 0.0 2.9 3 0 0 3 3 2 1 NTPase AAA_29 PF13555.1 OAJ09845.1 - 0.0038 16.7 0.0 3.2 7.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.17 OAJ09845.1 - 0.0039 16.6 0.0 0.67 9.3 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_10 PF12846.2 OAJ09845.1 - 0.0065 15.9 2.0 3.5 6.9 0.0 3.7 4 1 1 5 5 5 1 AAA-like domain ATP_bind_1 PF03029.12 OAJ09845.1 - 0.011 15.3 0.0 0.88 9.0 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 OAJ09845.1 - 0.018 14.6 0.0 7 6.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 OAJ09845.1 - 0.044 13.3 0.0 14 5.2 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 OAJ09845.1 - 0.059 13.8 0.0 4.6 7.7 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Rsa3 PF14615.1 OAJ09845.1 - 0.11 11.7 2.6 1.6 8.0 0.3 2.7 2 0 0 2 2 2 0 Ribosome-assembly protein 3 PduV-EutP PF10662.4 OAJ09845.1 - 0.13 11.7 0.0 3 7.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 OAJ09845.1 - 0.15 12.3 0.0 0.15 12.3 0.0 3.6 4 1 0 4 4 2 0 AAA domain AAA_21 PF13304.1 OAJ09845.1 - 0.16 11.9 0.0 31 4.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain Tht1 PF04163.7 OAJ09845.1 - 0.4 9.0 0.1 0.65 8.3 0.1 1.2 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein AAA_13 PF13166.1 OAJ09845.1 - 0.42 9.0 6.1 0.71 8.2 4.2 1.3 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 OAJ09849.1 - 1.1e-272 906.4 0.0 1.2e-272 906.2 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.3 OAJ09849.1 - 0.13 11.9 2.4 0.26 11.0 1.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Prefoldin_2 PF01920.15 OAJ09849.1 - 0.3 10.8 5.6 0.059 13.1 0.3 2.3 3 0 0 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.5 OAJ09849.1 - 0.4 10.8 6.2 0.23 11.6 2.3 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Gp58 PF07902.6 OAJ09849.1 - 0.54 8.4 2.3 0.8 7.8 1.6 1.1 1 0 0 1 1 1 0 gp58-like protein FTA4 PF13093.1 OAJ09849.1 - 1.4 8.3 10.6 8.4 5.7 3.7 2.4 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Helicase_C PF00271.26 OAJ09850.1 - 4.4e-25 87.3 0.0 7e-25 86.6 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RVT_2 PF07727.9 OAJ09858.1 - 8.3e-81 270.5 0.0 1.1e-80 270.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09859.1 - 5.2e-26 91.1 0.0 9.3e-26 90.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ09859.1 - 7.6e-07 28.6 0.0 6.1e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ09859.1 - 0.0051 16.3 0.1 0.02 14.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Fer2_BFD PF04324.10 OAJ09859.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain TcpQ PF10671.4 OAJ09859.1 - 1.3 8.9 5.6 2.9 7.8 0.9 2.4 1 1 1 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q UBN2 PF14223.1 OAJ09860.1 - 8.6e-09 35.2 0.1 2.2e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 OAJ09860.1 - 2e-07 30.9 0.1 6e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2_2 PF14227.1 OAJ09860.1 - 0.0001 21.8 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Asp_protease_2 PF13650.1 OAJ09863.1 - 4e-06 27.2 0.0 1.3e-05 25.5 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 OAJ09863.1 - 7.3e-06 25.4 0.0 1.7e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 OAJ09863.1 - 1.8e-05 24.5 0.0 3.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 OAJ09863.1 - 5.5e-05 22.7 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ09863.1 - 0.00061 19.5 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 OAJ09863.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 OAJ09864.1 - 0.003 17.1 0.1 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Transposase_21 PF02992.9 OAJ09868.1 - 4.1e-13 48.9 0.0 7.4e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ09868.1 - 0.0021 17.5 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) FHA PF00498.21 OAJ09869.1 - 0.097 12.8 0.0 2.4 8.3 0.0 2.3 2 0 0 2 2 2 0 FHA domain GAPT PF11770.3 OAJ09878.1 - 0.24 11.0 0.2 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) NAD_binding_8 PF13450.1 OAJ09884.1 - 4.6e-10 39.3 0.1 8.1e-10 38.5 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 OAJ09884.1 - 5.3e-08 32.3 0.0 3.9e-05 22.9 0.0 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 OAJ09884.1 - 5.8e-05 23.2 0.0 0.00012 22.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ09884.1 - 0.0047 16.8 0.0 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAJ09884.1 - 0.01 14.9 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAJ09884.1 - 0.021 13.8 0.1 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 OAJ09884.1 - 0.024 13.1 0.1 0.035 12.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 OAJ09884.1 - 0.035 12.9 0.1 0.057 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 OAJ09884.1 - 0.039 13.0 0.0 0.094 11.7 0.0 1.6 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 OAJ09884.1 - 0.04 12.7 0.0 0.061 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 OAJ09884.1 - 0.11 11.4 0.3 0.33 9.8 0.2 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 OAJ09884.1 - 0.18 11.5 0.0 0.18 11.5 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding DSHCT PF08148.7 OAJ09885.1 - 1.9e-24 85.9 0.1 2e-24 85.8 0.1 1.0 1 0 0 1 1 1 1 DSHCT (NUC185) domain ArsC PF03960.10 OAJ09885.1 - 0.09 12.8 0.0 0.093 12.8 0.0 1.0 1 0 0 1 1 1 0 ArsC family Uds1 PF15456.1 OAJ09887.1 - 0.015 15.2 1.9 0.023 14.6 0.6 1.8 2 0 0 2 2 2 0 Up-regulated During Septation Seryl_tRNA_N PF02403.17 OAJ09887.1 - 0.055 13.4 3.4 0.28 11.2 0.5 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain eIF-3c_N PF05470.7 OAJ09887.1 - 0.063 11.3 0.3 0.087 10.8 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCRF PF03462.13 OAJ09887.1 - 0.26 10.9 1.3 0.39 10.4 0.1 1.8 2 0 0 2 2 2 0 PCRF domain GAS PF13851.1 OAJ09887.1 - 0.71 9.0 9.0 4.4 6.4 0.1 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding EMP70 PF02990.11 OAJ09895.1 - 5.6e-170 566.2 0.0 6.8e-170 565.9 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 NPBW PF15180.1 OAJ09895.1 - 0.044 13.4 0.4 0.14 11.7 0.1 1.9 2 0 0 2 2 2 0 Neuropeptides B and W TFIIA PF03153.8 OAJ09896.1 - 0.13 12.1 5.2 0.17 11.7 3.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RVT_1 PF00078.22 OAJ09911.1 - 9.6e-24 83.9 0.0 1.6e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) eIF3_subunit PF08597.5 OAJ09919.1 - 0.00018 21.1 0.0 0.00018 21.1 0.0 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Zip PF02535.17 OAJ09919.1 - 0.093 11.7 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 OAJ09919.1 - 0.17 9.8 8.3 0.21 9.5 5.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF755 PF05501.6 OAJ09919.1 - 0.22 11.5 13.0 0.35 10.9 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RR_TM4-6 PF06459.7 OAJ09919.1 - 0.38 10.6 5.5 0.54 10.1 3.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_DNAp_acc PF04929.7 OAJ09919.1 - 1.4 7.7 8.5 1.7 7.5 5.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Med19 PF10278.4 OAJ09919.1 - 4.1 7.0 10.0 5.4 6.6 6.9 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RVT_1 PF00078.22 OAJ09926.1 - 7.9e-17 61.3 0.0 1.4e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09926.1 - 1.6e-13 50.8 0.0 3.3e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ09926.1 - 1.3e-06 28.8 0.2 6.3e-06 26.6 0.1 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ09926.1 - 0.0044 16.7 0.1 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ09926.1 - 0.38 10.7 0.0 0.9 9.5 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Macoilin PF09726.4 OAJ09936.1 - 0.53 8.4 25.4 1.7 6.8 17.6 1.8 1 1 0 1 1 1 0 Transmembrane protein SAPS PF04499.10 OAJ09936.1 - 2.2 6.7 14.8 0.016 13.8 1.8 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Fib_alpha PF08702.5 OAJ09936.1 - 3.3 7.8 10.4 11 6.1 7.0 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family GAS PF13851.1 OAJ09936.1 - 8.2 5.5 24.1 10 5.2 9.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Piwi PF02171.12 OAJ09943.1 - 7.7e-74 248.3 0.0 1.1e-73 247.9 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 OAJ09943.1 - 3e-16 58.9 0.0 9.6e-16 57.3 0.0 1.8 2 0 0 2 2 2 1 PAZ domain Alpha-amyl_C2 PF07821.7 OAJ09943.1 - 0.021 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Alpha-amylase C-terminal beta-sheet domain DUF1797 PF08796.5 OAJ09943.1 - 0.27 11.1 0.6 0.84 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) Mannosyl_trans PF05007.8 OAJ09944.1 - 5.4e-52 176.9 18.7 1.7e-47 162.2 10.9 3.5 2 1 0 2 2 2 2 Mannosyltransferase (PIG-M) F-box-like PF12937.2 OAJ09949.1 - 0.0002 21.0 0.6 0.00064 19.3 0.4 1.9 1 0 0 1 1 1 1 F-box-like Thg1 PF04446.7 OAJ09949.1 - 0.12 12.0 0.0 15 5.1 0.0 2.6 1 1 1 2 2 2 0 tRNAHis guanylyltransferase Thioredoxin PF00085.15 OAJ09950.1 - 7.4e-10 38.4 0.0 8.3e-10 38.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.19 OAJ09950.1 - 0.055 13.4 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin TatD_DNase PF01026.16 OAJ09951.1 - 3.1e-19 69.1 0.4 5.6e-19 68.3 0.2 1.4 1 0 0 1 1 1 1 TatD related DNase IF4E PF01652.13 OAJ09962.1 - 9.1e-44 148.8 0.6 5.6e-43 146.3 0.4 2.0 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E Mitofilin PF09731.4 OAJ09966.1 - 9.6e-07 27.8 2.1 1e-06 27.7 1.4 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein HhH-GPD PF00730.20 OAJ09967.1 - 2.8e-14 53.3 0.0 6.1e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 OAJ09967.1 - 5.1e-14 51.6 0.0 1.5e-13 50.2 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain Bul1_C PF04426.7 OAJ09967.1 - 0.011 14.9 2.1 0.022 13.9 1.4 1.4 1 0 0 1 1 1 0 Bul1 C terminus PG_binding_2 PF08823.6 OAJ09967.1 - 0.045 13.8 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain HHH PF00633.18 OAJ09967.1 - 0.047 13.4 0.1 0.13 11.9 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif SNase PF00565.12 OAJ09973.1 - 4.6e-21 75.0 2.4 2e-19 69.8 0.7 2.7 2 1 0 2 2 2 1 Staphylococcal nuclease homologue DUF3526 PF12040.3 OAJ09973.1 - 0.044 13.9 0.2 0.37 10.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3526) DUF4592 PF15262.1 OAJ09979.1 - 0.13 12.7 2.4 0.16 12.5 0.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4592) LSM14 PF12701.2 OAJ09980.1 - 5.9e-28 96.5 0.0 1.2e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 OAJ09980.1 - 1.1e-09 38.7 0.0 1.6e-08 35.0 0.0 2.8 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.1 OAJ09980.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Ataxin 2 SM domain CDC37_N PF03234.9 OAJ09981.1 - 2e-39 135.7 1.2 6.2e-38 130.8 0.8 2.5 1 1 0 1 1 1 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 OAJ09981.1 - 3.6e-21 75.4 0.7 5.4e-17 61.8 0.0 2.6 2 0 0 2 2 2 2 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 OAJ09981.1 - 5.8e-14 51.7 0.1 2.3e-13 49.8 0.0 2.0 1 0 0 1 1 1 1 Cdc37 C terminal domain Ldh_1_C PF02866.13 OAJ09986.1 - 2.6e-19 69.6 0.0 2.9e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Transposase_21 PF02992.9 OAJ09997.1 - 0.0057 15.7 0.0 0.0072 15.4 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 InaF-motif PF15018.1 OAJ09999.1 - 0.096 12.1 0.8 0.15 11.4 0.2 1.6 2 0 0 2 2 2 0 TRP-interacting helix DUF4218 PF13960.1 OAJ10001.1 - 0.027 13.8 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) UBN2 PF14223.1 OAJ10006.1 - 1.1e-06 28.4 0.0 5.1e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ10006.1 - 7.7e-05 22.4 2.2 0.00017 21.3 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ10006.1 - 0.092 12.4 0.9 0.19 11.4 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 OAJ10006.1 - 0.66 9.5 2.9 0.49 9.9 0.2 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RVT_2 PF07727.9 OAJ10007.1 - 8.3e-85 283.6 0.0 1.1e-84 283.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAJ10007.1 - 0.07 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) GTP_EFTU PF00009.22 OAJ10015.1 - 7.1e-49 165.8 0.0 1.2e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 OAJ10015.1 - 1.2e-34 118.4 0.1 2.3e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 OAJ10015.1 - 3e-13 49.4 0.0 7.4e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 OAJ10015.1 - 1.3e-05 25.2 0.2 2.7e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 OAJ10015.1 - 0.00012 21.8 0.0 0.00029 20.6 0.0 1.7 1 1 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 OAJ10015.1 - 0.0032 16.7 0.0 0.0065 15.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 OAJ10015.1 - 0.032 14.7 0.0 0.065 13.7 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein RR_TM4-6 PF06459.7 OAJ10028.1 - 2.2 8.0 5.8 3.9 7.2 4.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.3 OAJ10028.1 - 4 6.0 9.4 5.9 5.5 6.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Hid1 PF12722.2 OAJ10028.1 - 4.2 4.9 4.8 6.3 4.3 3.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2201_N PF13203.1 OAJ10028.1 - 6.5 5.8 13.4 0.48 9.5 5.7 1.7 2 0 0 2 2 2 0 Putative metallopeptidase domain TAP35_44 PF07265.6 OAJ10035.1 - 0.022 14.5 0.1 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 Polysacc_deac_1 PF01522.16 OAJ10042.1 - 1.1e-22 79.9 0.0 2e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 OAJ10042.1 - 0.011 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 zf-CCHC PF00098.18 OAJ10043.1 - 0.00065 19.5 5.2 0.0014 18.4 3.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ10043.1 - 0.035 13.8 0.4 0.082 12.6 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle TPR_14 PF13428.1 OAJ10057.1 - 8.3e-08 32.2 17.4 0.22 12.2 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ10057.1 - 5.2e-06 25.9 1.0 0.13 12.2 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ10057.1 - 4.7e-05 22.8 0.1 0.026 14.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ10057.1 - 0.00035 20.1 1.1 0.43 10.4 0.1 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ10057.1 - 0.0005 19.6 0.0 0.22 11.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ10057.1 - 0.0062 16.1 3.2 2.6 7.7 0.2 3.1 3 1 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 OAJ10057.1 - 0.012 16.2 18.5 0.88 10.3 0.0 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ10057.1 - 0.018 15.4 16.6 5.3 7.7 0.4 5.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ10057.1 - 0.035 14.0 12.9 0.33 10.9 0.2 4.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ10057.1 - 5.1 7.7 5.9 34 5.1 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat FmrO PF07091.6 OAJ10060.1 - 0.078 11.9 0.1 0.22 10.4 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) TFIIA PF03153.8 OAJ10065.1 - 0.16 11.8 9.9 0.18 11.6 6.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 OAJ10065.1 - 0.16 10.2 24.9 0.18 9.9 17.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4207 PF13904.1 OAJ10066.1 - 0.026 13.9 6.3 0.038 13.3 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DUF2477 PF10631.4 OAJ10066.1 - 0.036 14.2 0.9 0.055 13.6 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Dimer_Tnp_hAT PF05699.9 OAJ10067.1 - 2.6e-25 87.8 0.1 4e-25 87.2 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Prp19_bind PF06991.6 OAJ10067.1 - 0.05 12.8 0.0 0.083 12.1 0.0 1.3 1 1 0 1 1 1 0 Splicing factor, Prp19-binding domain WD40 PF00400.27 OAJ10075.1 - 2.4e-13 49.3 20.0 2.8e-05 23.8 0.1 6.3 5 1 0 5 5 5 3 WD domain, G-beta repeat RWD PF05773.17 OAJ10075.1 - 0.01 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 RWD domain TFIIF_alpha PF05793.7 OAJ10083.1 - 9.2 4.5 8.4 14 3.8 5.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-RING_2 PF13639.1 OAJ10091.1 - 5.3e-08 32.5 1.1 2.2e-07 30.5 0.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 OAJ10091.1 - 3.8e-06 26.5 1.4 1.6e-05 24.5 0.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ10091.1 - 1e-05 25.1 0.8 2.9e-05 23.7 0.1 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 OAJ10091.1 - 7e-05 22.7 0.3 7e-05 22.7 0.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ10091.1 - 7.7e-05 22.2 0.1 7.7e-05 22.2 0.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 OAJ10091.1 - 0.0023 18.0 0.1 0.0061 16.6 0.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 OAJ10091.1 - 0.0027 17.3 0.2 0.0027 17.3 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Peptidase_C27 PF05407.7 OAJ10092.1 - 0.048 13.3 3.1 0.055 13.1 2.1 1.1 1 0 0 1 1 1 0 Rubella virus endopeptidase HEAT_EZ PF13513.1 OAJ10097.1 - 1.2e-09 38.3 17.5 0.057 13.9 0.3 6.9 4 2 4 8 8 8 3 HEAT-like repeat HEAT PF02985.17 OAJ10097.1 - 3.4e-06 26.6 10.8 4.9 7.4 0.0 8.0 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.1 OAJ10097.1 - 0.00058 20.0 20.1 0.0067 16.6 0.9 5.8 3 2 0 5 5 5 2 HEAT repeats ParcG PF10274.4 OAJ10097.1 - 0.0027 17.6 0.0 0.039 13.8 0.0 2.6 3 0 0 3 3 3 1 Parkin co-regulated protein DUF3647 PF12363.3 OAJ10097.1 - 0.0047 17.0 0.1 0.097 12.7 0.0 2.7 3 0 0 3 3 3 1 Phage protein tRNA_synt_2f PF02092.12 OAJ10097.1 - 0.039 12.5 0.7 0.093 11.2 0.1 1.8 2 0 0 2 2 2 0 Glycyl-tRNA synthetase beta subunit RIX1 PF08167.7 OAJ10097.1 - 0.069 12.8 0.4 2.5 7.7 0.0 3.1 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.11 OAJ10097.1 - 3.6 8.3 11.3 1.1 9.9 0.2 4.9 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DDE_Tnp_4 PF13359.1 OAJ10104.1 - 7.4e-13 48.3 0.0 9.2e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.1 OAJ10104.1 - 0.011 15.9 0.1 0.021 15.0 0.1 1.5 1 0 0 1 1 1 0 Transposase DDE domain Plant_tran PF04827.9 OAJ10104.1 - 0.019 14.3 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein DDE_Tnp_1 PF01609.16 OAJ10104.1 - 0.049 13.1 0.6 0.17 11.4 0.4 1.9 1 1 0 1 1 1 0 Transposase DDE domain Transposase_21 PF02992.9 OAJ10111.1 - 0.0019 17.3 0.0 0.004 16.2 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 KIF1B PF12423.3 OAJ10111.1 - 0.051 13.6 0.2 0.16 12.0 0.1 1.8 1 0 0 1 1 1 0 Kinesin protein 1B CDC45 PF02724.9 OAJ10112.1 - 0.091 10.7 5.7 0.11 10.5 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Uds1 PF15456.1 OAJ10112.1 - 0.22 11.5 3.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Sigma70_ner PF04546.8 OAJ10112.1 - 0.31 10.6 6.6 2.6 7.6 3.8 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region RVT_1 PF00078.22 OAJ10121.1 - 2.7e-15 56.3 0.0 4.2e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spc97_Spc98 PF04130.8 OAJ10121.1 - 0.013 13.7 0.2 0.02 13.1 0.1 1.2 1 0 0 1 1 1 0 Spc97 / Spc98 family MULE PF10551.4 OAJ10130.1 - 6.7e-09 35.7 0.3 4.2e-08 33.2 0.1 2.4 3 0 0 3 3 3 1 MULE transposase domain SWIM PF04434.12 OAJ10130.1 - 0.00023 20.5 1.3 0.00069 19.0 0.9 1.8 1 0 0 1 1 1 1 SWIM zinc finger PGK PF00162.14 OAJ10137.1 - 3.2e-150 499.9 2.9 3.7e-150 499.7 2.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase NTF2 PF02136.15 OAJ10138.1 - 8e-34 116.5 0.2 9.7e-34 116.2 0.1 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain PAXIP1_C PF15364.1 OAJ10139.1 - 3.7 7.4 13.0 0.12 12.2 1.5 2.4 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein TFIID_30kDa PF03540.8 OAJ10140.1 - 7.7e-26 89.6 0.0 1.3e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CBS PF00571.23 OAJ10140.1 - 4.2e-05 23.2 0.1 0.0077 16.0 0.1 2.5 2 0 0 2 2 2 2 CBS domain Ribosomal_60s PF00428.14 OAJ10140.1 - 0.42 11.0 0.1 0.42 11.0 0.1 3.2 4 0 0 4 4 4 0 60s Acidic ribosomal protein FoP_duplication PF13865.1 OAJ10140.1 - 2.8 8.4 4.4 1.3 9.5 0.2 2.4 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 GIT_SHD PF08518.6 OAJ10145.1 - 2.5e-24 84.3 8.7 1.9e-14 52.6 0.8 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF3584 PF12128.3 OAJ10145.1 - 0.17 9.2 24.5 0.42 7.8 17.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 OAJ10145.1 - 0.38 9.1 19.4 1.4 7.2 13.3 1.8 1 1 0 1 1 1 0 AAA domain APG6 PF04111.7 OAJ10145.1 - 4.1 6.3 33.1 0.082 11.9 11.7 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 FKBP_C PF00254.23 OAJ10146.1 - 2.6e-34 117.0 0.4 1e-32 112.0 0.0 2.3 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Apolipoprotein PF01442.13 OAJ10146.1 - 2.5e-05 23.8 9.5 3.3e-05 23.4 6.6 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Phasin_2 PF09361.5 OAJ10146.1 - 0.013 15.5 16.6 0.013 15.5 11.5 2.1 1 1 1 2 2 2 0 Phasin protein DUF883 PF05957.8 OAJ10146.1 - 0.073 13.4 16.4 0.21 11.9 3.9 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 OAJ10146.1 - 0.57 10.5 19.2 2.9e+03 -1.3 12.8 3.3 2 1 0 2 2 2 0 YtxH-like protein Prominin PF05478.6 OAJ10146.1 - 0.69 7.3 6.2 0.83 7.1 4.3 1.1 1 0 0 1 1 1 0 Prominin Borrelia_P83 PF05262.6 OAJ10146.1 - 1.3 7.2 17.9 1.8 6.7 12.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein HisKA_3 PF07730.8 OAJ10146.1 - 2.3 8.6 5.7 84 3.6 4.0 3.0 1 1 0 1 1 1 0 Histidine kinase DUF1508 PF07411.7 OAJ10146.1 - 3.9 6.9 11.9 6.3 6.3 0.3 4.1 2 2 2 4 4 4 0 Domain of unknown function (DUF1508) Acyltransferase PF01553.16 OAJ10151.1 - 1.2e-23 82.9 0.0 2e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Form-deh_trans PF09163.6 OAJ10151.1 - 0.043 13.3 0.2 0.081 12.4 0.1 1.4 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane MIP-T3 PF10243.4 OAJ10156.1 - 0.051 12.0 11.8 0.069 11.6 8.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Peptidase_M23 PF01551.17 OAJ10157.1 - 0.00016 21.6 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M23 RVT_1 PF00078.22 OAJ10164.1 - 1.8e-19 69.9 0.0 3.4e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10164.1 - 7.5e-14 51.8 0.0 1.5e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ10164.1 - 0.0008 19.8 0.0 0.0033 17.8 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAJ10164.1 - 0.21 11.5 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease PEP-utilisers_N PF05524.8 OAJ10172.1 - 0.032 14.0 1.2 0.081 12.7 0.9 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal SseC PF04888.7 OAJ10172.1 - 0.33 10.2 6.6 0.19 10.9 1.7 2.0 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Baculo_PEP_C PF04513.7 OAJ10172.1 - 0.81 9.5 4.2 0.32 10.8 0.9 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HTH_28 PF13518.1 OAJ10173.1 - 0.0025 17.7 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 OAJ10173.1 - 0.0074 15.9 0.3 0.02 14.5 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 OAJ10173.1 - 0.017 15.0 0.3 0.064 13.2 0.1 2.1 2 0 0 2 2 2 0 Transposase Coatomer_WDAD PF04053.9 OAJ10177.1 - 3.6e-103 345.7 0.0 1.1e-70 238.6 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region 7TMR-HDED PF07697.6 OAJ10178.1 - 0.045 13.4 0.1 0.061 13.0 0.1 1.2 1 0 0 1 1 1 0 7TM-HD extracellular DUF2937 PF11157.3 OAJ10178.1 - 0.096 12.0 0.2 0.18 11.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) rve PF00665.21 OAJ10199.1 - 4.6e-17 62.2 0.0 1.6e-16 60.4 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ10199.1 - 5.3e-16 58.6 0.0 1.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 OAJ10199.1 - 0.0031 17.0 0.0 0.013 15.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain DUF2268 PF10026.4 OAJ10199.1 - 0.048 13.0 0.7 0.1 11.9 0.5 1.5 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) PEPCK_ATP PF01293.15 OAJ10204.1 - 7.8e-214 710.4 0.0 9.3e-214 710.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 OAJ10204.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAJ10204.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Histone PF00125.19 OAJ10211.1 - 6.3e-27 93.5 0.8 1.6e-26 92.1 0.5 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ10211.1 - 0.00085 19.4 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S DUF4413 PF14372.1 OAJ10211.1 - 0.008 16.1 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) F-box PF00646.28 OAJ10219.1 - 9e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ10219.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 F-box-like Vinculin PF01044.14 OAJ10221.1 - 0.12 10.3 0.2 0.17 9.8 0.1 1.1 1 0 0 1 1 1 0 Vinculin family UBN2 PF14223.1 OAJ10228.1 - 2.1e-06 27.5 0.0 4.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ10228.1 - 2.3e-05 24.1 1.8 5.7e-05 22.8 1.3 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ10228.1 - 0.0047 16.3 0.1 0.014 14.8 0.1 1.8 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 OAJ10228.1 - 0.073 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_5 PF14787.1 OAJ10228.1 - 0.72 9.3 2.6 0.98 8.9 0.2 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RVT_2 PF07727.9 OAJ10229.1 - 3.1e-85 285.0 0.0 4.4e-85 284.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10229.1 - 1.3e-19 70.4 0.1 5.8e-19 68.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ10229.1 - 7.8e-07 28.6 0.0 2.3e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ10229.1 - 7.5e-05 22.1 0.3 0.002 17.6 0.2 2.7 1 1 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ10229.1 - 0.02 14.2 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AF-4 PF05110.8 OAJ10229.1 - 0.41 8.4 3.0 0.6 7.9 2.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein HAUS5 PF14817.1 OAJ10236.1 - 0.018 13.6 1.1 0.02 13.4 0.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 YcbB PF08664.5 OAJ10236.1 - 0.028 14.2 0.2 0.034 13.9 0.2 1.1 1 0 0 1 1 1 0 YcbB domain Nup54 PF13874.1 OAJ10236.1 - 0.035 13.7 0.1 0.049 13.2 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 RNA_pol_Rpb1_6 PF04992.9 OAJ10236.1 - 0.044 13.5 0.2 0.054 13.2 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 7TMR-HDED PF07697.6 OAJ10236.1 - 0.064 12.9 0.6 0.068 12.8 0.4 1.1 1 0 0 1 1 1 0 7TM-HD extracellular Methyltrans_Mon PF14314.1 OAJ10236.1 - 0.065 11.0 0.2 0.069 10.9 0.1 1.0 1 0 0 1 1 1 0 Virus-capping methyltransferase DUF3347 PF11827.3 OAJ10236.1 - 0.069 13.1 0.4 0.085 12.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Ribosomal_L15e PF00827.12 OAJ10244.1 - 6.4e-88 293.2 8.4 7.6e-88 293.0 5.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L18p PF00861.17 OAJ10245.1 - 3.1e-39 133.8 1.5 4.6e-39 133.2 0.0 2.0 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 OAJ10245.1 - 1.8e-34 118.1 5.2 4.5e-34 116.8 3.6 1.7 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region MtrA PF04208.9 OAJ10245.1 - 0.053 12.9 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A UPF0449 PF15136.1 OAJ10245.1 - 0.11 12.7 1.0 0.21 11.7 0.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Phage_integrase PF00589.17 OAJ10254.1 - 5.2e-05 22.9 0.0 6.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family Cyclin_N PF00134.18 OAJ10255.1 - 4.3e-12 45.6 0.0 7.1e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 OAJ10255.1 - 6.1e-12 46.1 0.0 1.2e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin Isochorismatase PF00857.15 OAJ10256.1 - 3e-32 111.9 0.2 3.8e-32 111.6 0.2 1.1 1 0 0 1 1 1 1 Isochorismatase family DDE_Tnp_IS1595 PF12762.2 OAJ10256.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 ISXO2-like transposase domain CMAS PF02353.15 OAJ10261.1 - 7.6e-56 189.1 0.0 1.8e-51 174.8 0.0 2.9 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 OAJ10261.1 - 6.3e-11 42.8 0.0 1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ10261.1 - 2e-09 37.3 0.0 5.4e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ10261.1 - 5.1e-08 33.2 0.0 1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ10261.1 - 1.7e-07 30.9 0.0 2.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ10261.1 - 2.1e-06 27.7 0.1 4.7e-06 26.6 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ10261.1 - 8e-05 23.0 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ10261.1 - 0.0002 21.6 0.0 0.00039 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 OAJ10261.1 - 0.0007 19.2 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_24 PF13578.1 OAJ10261.1 - 0.0056 17.5 0.0 0.013 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 OAJ10261.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.9 OAJ10261.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 OAJ10261.1 - 0.044 13.2 0.0 0.13 11.7 0.0 1.6 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.5 OAJ10261.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_3 PF01596.12 OAJ10261.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DUF3184 PF11380.3 OAJ10262.1 - 3.8e-19 68.1 9.4 3.6e-11 41.7 0.3 4.2 2 1 1 3 3 3 3 Protein of unknown function (DUF3184) PAT1 PF09770.4 OAJ10262.1 - 2.5e-12 45.9 0.1 6.5e-12 44.5 0.0 1.7 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 SdpI PF13630.1 OAJ10262.1 - 0.024 14.3 0.3 0.049 13.3 0.2 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family CitMHS PF03600.11 OAJ10262.1 - 0.096 11.2 0.9 0.15 10.6 0.3 1.4 2 0 0 2 2 2 0 Citrate transporter PAT1 PF09770.4 OAJ10263.1 - 2.2e-18 65.9 0.2 4.6e-18 64.9 0.1 1.5 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 OPT PF03169.10 OAJ10270.1 - 6.4e-89 299.0 28.9 7.3e-89 298.8 20.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.10 OAJ10271.1 - 1.6e-74 251.4 23.9 1.9e-74 251.2 16.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1700 PF08006.6 OAJ10271.1 - 5 6.3 7.3 1.1 8.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Hydantoinase_A PF01968.13 OAJ10275.1 - 5.3e-88 294.8 3.1 8.1e-87 290.9 0.4 2.4 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 OAJ10275.1 - 7e-57 191.7 0.4 2e-54 183.7 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region DUF3053 PF11254.3 OAJ10276.1 - 0.039 13.2 0.3 0.063 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) DUF3169 PF11368.3 OAJ10276.1 - 0.44 9.7 1.1 0.87 8.7 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) FRQ PF09421.5 OAJ10276.1 - 4 5.0 7.3 6.3 4.4 5.1 1.2 1 0 0 1 1 1 0 Frequency clock protein PAPA-1 PF04795.7 OAJ10282.1 - 5.5e-14 52.6 19.0 1e-13 51.7 5.7 3.8 2 2 0 2 2 2 1 PAPA-1-like conserved region Daxx PF03344.10 OAJ10282.1 - 0.003 16.1 32.2 0.003 16.1 22.3 2.1 2 0 0 2 2 2 2 Daxx Family Mito_carr PF00153.22 OAJ10283.1 - 2.3e-53 177.8 5.2 2.2e-17 62.5 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.2 OAJ10283.1 - 1.8 8.9 5.2 0.2 12.0 0.2 2.0 2 0 0 2 2 2 0 YtxH-like protein RVT_1 PF00078.22 OAJ10288.1 - 1.3e-05 24.7 0.0 2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ10288.1 - 4e-05 24.0 0.0 8.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ10288.1 - 0.0059 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ10288.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease rve PF00665.21 OAJ10290.1 - 5.8e-12 45.7 0.0 1.5e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Helicase_C PF00271.26 OAJ10296.1 - 5.1e-08 32.6 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ10296.1 - 1.4e-05 24.6 0.0 3.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C2H2 PF00096.21 OAJ10296.1 - 0.0076 16.5 2.7 0.0076 16.5 1.8 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ10296.1 - 0.014 15.7 6.2 0.41 11.0 1.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 OAJ10296.1 - 0.15 12.1 6.2 0.87 9.7 0.2 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 OAJ10296.1 - 0.28 11.1 5.3 0.52 10.3 0.7 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.1 OAJ10296.1 - 3.5 8.0 11.8 8 6.9 4.0 3.3 2 1 0 2 2 2 0 Zinc-finger double domain Pex14_N PF04695.8 OAJ10300.1 - 1.9 8.5 6.5 1.1 9.3 0.1 2.3 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RVT_1 PF00078.22 OAJ10301.1 - 1.5e-14 53.8 0.0 3.9e-14 52.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CAV_VP3 PF04771.7 OAJ10301.1 - 0.048 13.6 0.4 9 6.2 0.1 2.4 2 0 0 2 2 2 0 Chicken anaemia virus VP-3 protein APG6 PF04111.7 OAJ10305.1 - 0.0015 17.6 5.3 0.0015 17.6 3.7 2.1 2 0 0 2 2 2 1 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 OAJ10305.1 - 0.0021 17.7 3.5 0.0021 17.7 2.4 2.5 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 OAJ10305.1 - 0.0046 16.8 14.0 0.0046 16.8 9.7 2.8 2 2 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 OAJ10305.1 - 0.0052 16.3 10.9 0.0052 16.3 7.6 2.2 2 0 0 2 2 2 1 IncA protein GAS PF13851.1 OAJ10305.1 - 0.13 11.4 8.0 0.1 11.7 1.0 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Glyco_hydro_9 PF00759.14 OAJ10306.1 - 1.9e-83 280.8 4.3 2.3e-49 168.5 1.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 9 PP2C PF00481.16 OAJ10306.1 - 6.2e-12 45.4 0.0 1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PAT1 PF09770.4 OAJ10316.1 - 6 4.9 10.8 6.5 4.8 7.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tyrosinase PF00264.15 OAJ10325.1 - 1.1e-33 117.3 2.1 1.1e-33 117.3 1.5 2.1 2 0 0 2 2 2 1 Common central domain of tyrosinase Adaptin_binding PF10199.4 OAJ10325.1 - 0.00035 20.8 11.2 0.00035 20.8 7.8 1.9 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 RNA_polI_A34 PF08208.6 OAJ10325.1 - 0.0073 15.9 21.0 0.012 15.3 14.6 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Med19 PF10278.4 OAJ10325.1 - 0.024 14.3 12.5 0.035 13.7 8.7 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Cellulose_synt PF03552.9 OAJ10325.1 - 0.34 9.1 2.5 0.48 8.6 1.8 1.1 1 0 0 1 1 1 0 Cellulose synthase VID27 PF08553.5 OAJ10325.1 - 1.5 6.9 20.9 1.9 6.5 14.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Pox_Ag35 PF03286.9 OAJ10325.1 - 2.5 7.5 26.0 3.8 6.9 18.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFIIF_alpha PF05793.7 OAJ10325.1 - 2.8 6.2 37.1 3.9 5.7 25.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4175 PF13779.1 OAJ10325.1 - 4.3 4.9 19.2 6.1 4.4 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Nucleo_P87 PF07267.6 OAJ10325.1 - 5 5.6 12.4 7.3 5.1 8.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Spore_coat_CotO PF14153.1 OAJ10325.1 - 6.2 6.2 26.2 11 5.3 18.2 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Helicase_C PF00271.26 OAJ10333.1 - 5.4e-10 38.9 0.0 1.2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GP40 PF11025.3 OAJ10334.1 - 0.18 11.3 1.5 0.3 10.6 1.0 1.3 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Proteasome PF00227.21 OAJ10340.1 - 1.5e-41 141.7 0.1 1.9e-41 141.4 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit DnaJ-X PF14308.1 OAJ10341.1 - 3.1e-60 202.9 4.8 1.1e-58 197.8 0.2 2.3 2 0 0 2 2 2 2 X-domain of DnaJ-containing DnaJ PF00226.26 OAJ10341.1 - 1.8e-18 66.0 0.2 1.8e-18 66.0 0.2 2.7 4 0 0 4 4 4 1 DnaJ domain FAM70 PF14967.1 OAJ10341.1 - 1.3 8.1 3.2 2 7.5 2.2 1.1 1 0 0 1 1 1 0 FAM70 protein EcKinase PF02958.15 OAJ10352.1 - 4.7e-20 71.9 0.0 3.6e-19 69.0 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 OAJ10352.1 - 1.6e-07 31.2 1.9 3.5e-07 30.2 1.3 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 OAJ10352.1 - 1.9e-07 30.0 0.0 3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) SKG6 PF08693.5 OAJ10361.1 - 0.0096 15.2 0.0 0.038 13.3 0.0 2.1 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1191 PF06697.7 OAJ10361.1 - 0.012 14.5 0.1 0.053 12.3 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1191) Syndecan PF01034.15 OAJ10361.1 - 0.047 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain RAP1 PF07218.6 OAJ10362.1 - 1.5 6.8 9.1 2 6.4 6.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RVT_1 PF00078.22 OAJ10374.1 - 2.2e-17 63.1 0.0 4.1e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10374.1 - 4.3e-15 55.8 0.0 7.6e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ10375.1 - 0.00035 21.0 0.0 0.00079 19.8 0.0 1.7 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ10375.1 - 0.011 15.5 0.0 0.027 14.3 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease Toxin_58 PF15536.1 OAJ10381.1 - 0.13 12.1 1.5 0.17 11.7 1.0 1.1 1 0 0 1 1 1 0 Putative toxin 58 HSP70 PF00012.15 OAJ10383.1 - 1.3e-06 26.6 0.0 1.5e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Rax2 PF12768.2 OAJ10391.1 - 5.3e-82 275.1 1.2 3e-60 203.8 0.0 5.2 4 2 1 5 5 5 4 Cortical protein marker for cell polarity SH3_1 PF00018.23 OAJ10391.1 - 1e-14 53.6 0.0 1.9e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ10391.1 - 5.9e-12 44.9 0.0 1.4e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ10391.1 - 1.8e-07 30.5 0.0 3.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Kelch_2 PF07646.10 OAJ10391.1 - 0.11 12.2 6.1 8.8 6.2 0.0 4.8 5 0 0 5 5 5 0 Kelch motif SlyX PF04102.7 OAJ10396.1 - 0.44 10.9 0.1 0.44 10.9 0.1 3.0 3 0 0 3 3 3 0 SlyX zf-C2H2 PF00096.21 OAJ10396.1 - 0.53 10.7 4.5 2.2 8.8 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ10396.1 - 9.5 6.8 7.6 1.3 9.4 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF282 PF03380.9 OAJ10405.1 - 0.65 9.7 3.8 4.1 7.2 0.1 2.7 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF282 Helitron_like_N PF14214.1 OAJ10412.1 - 2.3e-12 47.0 0.1 5.7e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 OAJ10412.1 - 2.8e-10 39.7 0.0 4.4e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase MFS_1 PF07690.11 OAJ10423.1 - 2.7e-32 111.8 29.5 1.1e-30 106.6 5.5 2.9 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ10423.1 - 1.2e-09 37.2 1.1 1.2e-09 37.2 0.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Nucleoplasmin PF03066.10 OAJ10423.1 - 0.083 12.4 1.0 0.19 11.2 0.7 1.6 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 OAJ10423.1 - 0.21 9.5 7.1 0.32 8.8 4.9 1.1 1 0 0 1 1 1 0 Nop14-like family PGA2 PF07543.7 OAJ10423.1 - 3 7.6 8.3 17 5.2 0.1 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 NOA36 PF06524.7 OAJ10423.1 - 7.4 5.7 6.8 12 5.0 4.7 1.2 1 0 0 1 1 1 0 NOA36 protein RVT_1 PF00078.22 OAJ10427.1 - 4.1e-11 42.6 0.1 8e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 OAJ10427.1 - 1.4e-06 28.2 0.0 2.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_3 PF13917.1 OAJ10427.1 - 0.00032 20.3 0.1 0.00082 19.0 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 OAJ10427.1 - 0.00049 19.8 2.3 0.00098 18.9 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 OAJ10427.1 - 0.0022 17.5 0.4 0.0022 17.5 0.2 1.9 2 0 0 2 2 2 1 Zinc knuckle Asp_protease_2 PF13650.1 OAJ10427.1 - 0.015 15.7 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.1 OAJ10427.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 OAJ10427.1 - 0.045 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein RVP PF00077.15 OAJ10427.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_4 PF14392.1 OAJ10427.1 - 0.24 11.1 0.2 0.45 10.2 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle USP7_ICP0_bdg PF12436.3 OAJ10437.1 - 7.1e-81 271.1 0.0 2.1e-80 269.5 0.0 1.9 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 OAJ10437.1 - 1.3e-64 217.5 0.8 7.3e-63 211.8 0.3 2.9 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 OAJ10437.1 - 1.6e-54 184.8 0.1 4.4e-54 183.3 0.0 1.8 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ10437.1 - 3.1e-31 108.9 0.0 6.2e-31 107.9 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 OAJ10437.1 - 3.5e-08 33.7 0.3 8.3e-07 29.2 0.0 3.2 2 1 0 2 2 2 1 MATH domain zf-met PF12874.2 OAJ10443.1 - 3.5e-06 27.0 1.6 4.4e-06 26.6 0.6 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type ATP_transf PF09830.4 OAJ10444.1 - 1.4e-12 47.2 0.0 2.8e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 OAJ10444.1 - 0.014 15.8 0.0 0.045 14.2 0.0 1.8 1 0 0 1 1 1 0 HIT domain TBP PF00352.16 OAJ10445.1 - 8.6e-69 226.9 0.2 1.6e-34 117.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 OAJ10445.1 - 0.00011 22.1 0.0 0.45 10.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Asp PF00026.18 OAJ10455.1 - 1.2e-17 64.1 0.0 1.8e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease AAA_5 PF07728.9 OAJ10456.1 - 1.1e-26 93.2 0.0 2.5e-26 92.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) VWA_2 PF13519.1 OAJ10456.1 - 1.4e-06 28.5 0.2 3.3e-06 27.3 0.2 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_22 PF13401.1 OAJ10456.1 - 0.0013 18.8 0.0 0.0058 16.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ10456.1 - 0.0026 17.7 0.9 1.2 9.1 0.0 3.7 3 1 1 4 4 4 1 AAA ATPase domain HI0933_like PF03486.9 OAJ10456.1 - 0.047 12.1 2.1 0.078 11.4 1.4 1.3 1 0 0 1 1 1 0 HI0933-like protein COMP PF11598.3 OAJ10456.1 - 1.2 9.2 4.8 12 6.0 0.6 3.1 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein ABC_membrane PF00664.18 OAJ10461.1 - 5.2e-61 206.4 25.0 5.2e-32 111.3 7.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ10461.1 - 3.7e-59 198.9 0.0 4.9e-29 101.3 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAJ10461.1 - 3.3e-16 59.1 2.4 6.8e-08 32.0 0.6 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 OAJ10461.1 - 1.8e-09 36.9 0.0 0.00061 19.0 0.0 2.6 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAJ10461.1 - 8e-09 36.3 0.3 0.00023 21.9 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAJ10461.1 - 3.5e-08 32.8 2.6 0.00059 19.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 OAJ10461.1 - 4.2e-08 33.5 0.1 0.21 11.4 0.0 4.3 3 1 0 4 4 4 2 AAA domain AAA_16 PF13191.1 OAJ10461.1 - 5.8e-07 29.6 1.0 0.075 13.0 0.1 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 OAJ10461.1 - 5.3e-06 26.6 0.3 0.06 13.4 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 OAJ10461.1 - 8e-06 26.1 0.1 0.006 16.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain ABC_ATPase PF09818.4 OAJ10461.1 - 3.3e-05 22.6 0.2 0.15 10.5 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.1 OAJ10461.1 - 6.9e-05 22.3 0.1 0.18 11.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 OAJ10461.1 - 8.9e-05 22.3 2.1 0.013 15.4 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_10 PF12846.2 OAJ10461.1 - 0.00034 20.1 4.5 1.3 8.4 0.1 3.5 3 0 0 3 3 3 2 AAA-like domain DUF3987 PF13148.1 OAJ10461.1 - 0.00047 18.8 1.3 0.00047 18.8 0.9 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3987) AAA_23 PF13476.1 OAJ10461.1 - 0.00061 20.1 2.6 0.038 14.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 OAJ10461.1 - 0.0014 18.5 4.0 0.54 10.2 0.2 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.24 OAJ10461.1 - 0.002 18.3 0.2 0.5 10.5 0.0 3.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 OAJ10461.1 - 0.0026 17.7 0.2 3 7.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 OAJ10461.1 - 0.0037 16.9 0.0 0.62 9.7 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 OAJ10461.1 - 0.008 15.6 0.0 3.6 7.0 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 OAJ10461.1 - 0.022 14.5 0.9 0.4 10.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 OAJ10461.1 - 0.024 13.7 2.6 0.3 10.1 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_14 PF13173.1 OAJ10461.1 - 0.042 13.7 0.0 0.31 10.9 0.0 2.4 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 OAJ10461.1 - 0.046 13.8 0.0 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 OAJ10461.1 - 0.085 12.5 0.0 3.3 7.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.18 OAJ10461.1 - 0.093 12.5 0.6 15 5.3 0.0 2.9 3 0 0 3 3 3 0 Dynamin family DUF2075 PF09848.4 OAJ10461.1 - 0.11 11.4 0.2 0.24 10.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_15 PF13175.1 OAJ10461.1 - 0.35 9.8 0.0 0.78 8.7 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain Sugar_tr PF00083.19 OAJ10468.1 - 2.7e-08 32.8 0.1 4.1e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter ATP-synt_DE_N PF02823.11 OAJ10468.1 - 0.00056 19.6 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain adh_short PF00106.20 OAJ10469.1 - 9.2e-11 41.9 0.1 1.1e-10 41.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ10469.1 - 2.4e-06 27.4 0.2 3.4e-06 27.0 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ10469.1 - 0.079 12.6 0.1 0.092 12.4 0.1 1.2 1 0 0 1 1 1 0 KR domain PIGA PF08288.7 OAJ10473.1 - 3.6e-41 139.4 0.0 7.4e-41 138.4 0.0 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 OAJ10473.1 - 1.7e-25 89.3 0.0 2.6e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 OAJ10473.1 - 1.2e-15 57.6 0.4 3.2e-15 56.2 0.3 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 OAJ10473.1 - 1.6e-15 57.5 2.5 5.9e-15 55.7 0.2 2.5 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 OAJ10473.1 - 2.3e-11 43.9 0.0 4.5e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 OAJ10473.1 - 0.00019 21.2 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 OAJ10473.1 - 0.00064 19.9 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 rve PF00665.21 OAJ10487.1 - 1.3e-15 57.5 0.0 2.4e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ10487.1 - 5.7e-05 22.5 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 OAJ10487.1 - 0.07 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease_2 PF13650.1 OAJ10488.1 - 0.00037 20.9 0.0 0.00095 19.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ10488.1 - 0.0075 16.0 0.0 0.061 13.1 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ10488.1 - 0.013 15.4 0.0 0.043 13.7 0.0 1.9 1 1 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.22 OAJ10488.1 - 0.093 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PsbH PF00737.15 OAJ10496.1 - 0.56 9.8 3.4 4.8 6.8 0.3 2.5 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein RVT_1 PF00078.22 OAJ10504.1 - 1.9e-29 102.6 0.0 2.9e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ10504.1 - 2.9e-07 30.1 0.0 5.9e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ10504.1 - 6.4e-07 29.5 0.1 1.4e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family rve PF00665.21 OAJ10507.1 - 2.8e-18 66.1 0.0 7.5e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ10507.1 - 5.9e-14 51.9 0.0 1.2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 OAJ10507.1 - 0.00058 19.3 0.0 0.0016 17.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 OAJ10507.1 - 1.8 8.6 4.6 0.24 11.3 0.1 1.9 3 0 0 3 3 3 0 Zinc knuckle Med8 PF10232.4 OAJ10516.1 - 0.087 12.3 2.9 0.18 11.2 1.2 2.0 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 PPI_Ypi1 PF07491.6 OAJ10517.1 - 1.2e-25 88.9 1.7 7.9e-25 86.2 1.2 2.5 1 1 0 1 1 1 1 Protein phosphatase inhibitor Nop14 PF04147.7 OAJ10517.1 - 0.00088 17.3 0.7 0.00088 17.3 0.5 1.7 2 0 0 2 2 2 1 Nop14-like family CDC45 PF02724.9 OAJ10517.1 - 2.6 5.9 11.0 0.032 12.2 2.2 1.6 2 0 0 2 2 2 0 CDC45-like protein Histidinol_dh PF00815.15 OAJ10518.1 - 5.8e-166 552.2 0.4 1.5e-163 544.2 0.3 2.1 1 1 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 OAJ10518.1 - 2.7e-21 74.9 0.2 5.3e-21 74.0 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 OAJ10518.1 - 1.5e-11 44.3 0.9 1.5e-11 44.3 0.6 2.3 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 OAJ10518.1 - 0.0014 18.5 0.2 0.0027 17.5 0.2 1.5 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain DUF460 PF04312.8 OAJ10518.1 - 0.012 15.1 0.1 0.029 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Helicase_C PF00271.26 OAJ10527.1 - 3.2e-12 46.1 0.0 7.2e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Phage_integrase PF00589.17 OAJ10527.1 - 0.042 13.5 0.0 5.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Phage integrase family DEAD PF00270.24 OAJ10527.1 - 0.048 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Guanylate_cyc_2 PF09778.4 OAJ10528.1 - 0.028 13.5 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Guanylylate cyclase zf-C3HC4_3 PF13920.1 OAJ10534.1 - 1.4 8.6 9.0 0.2 11.3 1.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ10534.1 - 3.5 7.4 9.9 2.3 8.0 1.7 2.3 2 0 0 2 2 2 0 zinc-RING finger domain MULE PF10551.4 OAJ10535.1 - 7.3e-19 67.7 0.0 1.7e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ10535.1 - 8.5e-07 27.8 0.0 1.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family Fis1_TPR_N PF14852.1 OAJ10535.1 - 0.089 12.1 0.0 0.26 10.6 0.0 1.7 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat Mcp5_PH PF12814.2 OAJ10546.1 - 0.07 13.0 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PQQ PF01011.16 OAJ10547.1 - 0.0021 17.4 0.7 0.39 10.3 0.0 2.9 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.1 OAJ10547.1 - 0.039 13.4 0.1 0.65 9.4 0.1 2.4 2 1 0 2 2 2 0 PQQ-like domain F-box PF00646.28 OAJ10548.1 - 3.7e-05 23.2 0.4 6e-05 22.5 0.3 1.3 1 0 0 1 1 1 1 F-box domain Fer2_BFD PF04324.10 OAJ10557.1 - 0.19 11.7 0.3 0.41 10.7 0.2 1.6 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain Dimer_Tnp_hAT PF05699.9 OAJ10562.1 - 2.1e-14 52.8 0.0 4.6e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CorA PF01544.13 OAJ10562.1 - 0.15 11.0 2.7 0.27 10.2 1.9 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CobT PF06213.7 OAJ10562.1 - 0.49 9.4 14.1 1.3 8.0 9.8 1.7 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pkinase PF00069.20 OAJ10563.1 - 1.9e-38 132.1 0.0 2.6e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ10563.1 - 1.8e-17 63.2 0.0 3.2e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ10563.1 - 1.6e-07 30.5 0.0 2.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like adh_short_C2 PF13561.1 OAJ10569.1 - 3.4e-16 59.7 0.1 3.8e-16 59.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ10569.1 - 1.4e-05 25.0 0.1 2e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DDOST_48kD PF03345.9 OAJ10570.1 - 4.5e-82 275.8 0.0 4.5e-54 183.6 0.0 2.1 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta DUF3530 PF12048.3 OAJ10570.1 - 0.14 11.1 1.5 5.5 5.8 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3530) Phosphodiest PF01663.17 OAJ10571.1 - 0.00011 21.7 0.1 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase zf-TFIIB PF13453.1 OAJ10571.1 - 0.0058 15.7 0.0 0.018 14.2 0.0 1.8 2 0 0 2 2 2 1 Transcription factor zinc-finger RLAN PF14401.1 OAJ10580.1 - 0.0027 17.2 0.2 0.0049 16.3 0.1 1.6 1 1 0 1 1 1 1 RimK-like ATPgrasp N-terminal domain DUF4566 PF15130.1 OAJ10580.1 - 0.024 13.8 0.1 0.034 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) DUF4413 PF14372.1 OAJ10581.1 - 0.022 14.7 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Pkinase PF00069.20 OAJ10582.1 - 5.9e-27 94.4 0.0 7.6e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ10582.1 - 2.8e-16 59.3 0.0 3.6e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ10582.1 - 1.3e-07 30.8 0.0 2.1e-07 30.1 0.0 1.3 1 1 0 1 1 1 1 Kinase-like DUF1900 PF08954.6 OAJ10591.1 - 1.4e-46 157.4 0.0 6.6e-46 155.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 OAJ10591.1 - 6.1e-31 105.8 0.3 1.8e-30 104.3 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 OAJ10591.1 - 5e-16 57.8 1.5 7.3e-06 25.6 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat PAT1 PF09770.4 OAJ10591.1 - 0.51 8.5 3.1 0.68 8.1 2.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RNA_pol_Rpb8 PF03870.10 OAJ10592.1 - 2e-37 128.4 0.2 1.1e-35 122.8 0.1 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb8 polyprenyl_synt PF00348.12 OAJ10593.1 - 2.9e-46 157.4 0.0 1.2e-22 80.0 0.0 3.1 3 0 0 3 3 3 3 Polyprenyl synthetase DUF2296 PF10058.4 OAJ10594.1 - 3.3e-08 33.1 0.0 7e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Med15 PF09606.5 OAJ10594.1 - 0.35 9.0 27.9 0.42 8.7 19.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 OAJ10594.1 - 2.6 6.1 24.1 3.2 5.8 16.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 OAJ10594.1 - 5.7 6.2 15.2 7.6 5.8 10.5 1.1 1 0 0 1 1 1 0 Vta1 like Fe-ADH PF00465.14 OAJ10600.1 - 3.7e-93 312.0 0.0 4.8e-93 311.7 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 OAJ10600.1 - 1.4e-13 50.7 0.0 2.1e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase SH3_9 PF14604.1 OAJ10601.1 - 9.4e-06 25.1 0.1 0.00015 21.2 0.1 2.4 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ10601.1 - 2.8e-05 23.4 0.0 0.00013 21.2 0.0 2.1 2 0 0 2 2 2 1 SH3 domain Proteasome PF00227.21 OAJ10602.1 - 1.4e-59 200.6 0.0 2.3e-59 199.9 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 OAJ10602.1 - 3.1e-10 39.1 0.2 7.7e-10 37.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DNA_ligase_A_C PF04679.10 OAJ10609.1 - 0.13 12.6 0.1 0.26 11.7 0.1 1.5 1 1 0 1 1 1 0 ATP dependent DNA ligase C terminal region SH2_2 PF14633.1 OAJ10616.1 - 4.9e-66 221.9 0.1 1.2e-65 220.6 0.1 1.7 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 OAJ10616.1 - 1.3e-23 83.2 5.4 1.2e-22 80.1 0.0 3.8 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 OAJ10616.1 - 7e-23 80.7 0.0 1.4e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 OAJ10616.1 - 8.9e-20 70.7 1.3 4.5e-13 49.0 0.0 2.9 3 0 0 3 3 3 2 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 OAJ10616.1 - 1.3e-17 63.7 26.9 1.3e-17 63.7 18.7 6.6 5 1 2 7 7 7 2 Acidic N-terminal SPT6 SH2 PF00017.19 OAJ10616.1 - 0.00045 19.9 0.0 0.00094 18.9 0.0 1.6 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 OAJ10616.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif AAA_27 PF13514.1 OAJ10624.1 - 0.00021 19.1 0.4 0.00025 18.8 0.3 1.0 1 0 0 1 1 1 1 AAA domain Spectrin PF00435.16 OAJ10624.1 - 0.0086 16.3 0.8 0.018 15.3 0.6 1.5 1 1 0 1 1 1 1 Spectrin repeat Rab5-bind PF09311.6 OAJ10624.1 - 0.024 14.5 0.5 0.041 13.7 0.4 1.3 1 0 0 1 1 1 0 Rabaptin-like protein IncA PF04156.9 OAJ10624.1 - 0.074 12.6 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 IncA protein Uds1 PF15456.1 OAJ10624.1 - 0.079 12.9 1.2 0.12 12.4 0.9 1.2 1 0 0 1 1 1 0 Up-regulated During Septation BDV_P24 PF06595.6 OAJ10624.1 - 0.08 12.6 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Borna disease virus P24 protein Spore_II_R PF09551.5 OAJ10624.1 - 0.081 12.9 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) bZIP_1 PF00170.16 OAJ10624.1 - 0.11 12.5 3.7 0.11 12.4 0.4 2.1 1 1 1 2 2 2 0 bZIP transcription factor DUF4512 PF14975.1 OAJ10624.1 - 0.12 13.1 0.4 0.36 11.6 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) TMF_TATA_bd PF12325.3 OAJ10624.1 - 0.12 12.0 2.6 0.23 11.1 1.8 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CENP-Q PF13094.1 OAJ10624.1 - 0.69 9.9 4.4 1.4 8.9 3.0 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ETS_PEA3_N PF04621.8 OAJ10625.1 - 0.1 11.7 2.5 0.11 11.6 1.7 1.1 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain RVT_1 PF00078.22 OAJ10633.1 - 2.1e-07 30.5 0.0 5.3e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10634.1 - 3.6e-20 72.2 0.1 8.2e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ10634.1 - 0.0019 17.6 0.0 0.0047 16.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 OAJ10635.1 - 0.0015 18.3 2.5 0.0026 17.6 1.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ10635.1 - 0.017 14.6 0.6 0.035 13.6 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.1 OAJ10635.1 - 0.021 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAJ10635.1 - 0.03 14.7 0.0 0.062 13.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.22 OAJ10644.1 - 3.2e-19 69.1 0.0 5.9e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10644.1 - 4.1e-14 52.7 0.0 1.4e-13 50.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ10644.1 - 9.1e-05 22.8 0.0 0.00029 21.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ10644.1 - 0.022 14.6 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ10644.1 - 0.025 14.3 0.1 0.07 12.9 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Pkinase PF00069.20 OAJ10653.1 - 8.5e-72 241.4 0.1 4.5e-65 219.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ10653.1 - 1.9e-36 125.4 0.1 2.4e-33 115.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.14 OAJ10653.1 - 3.3e-18 64.8 0.4 5.8e-18 64.0 0.3 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 OAJ10653.1 - 3.1e-05 23.1 0.0 5.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ10653.1 - 0.00029 20.6 0.9 0.015 15.0 0.0 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ10653.1 - 0.0098 14.8 0.0 0.023 13.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like WaaY PF06176.6 OAJ10653.1 - 0.16 11.1 0.3 0.25 10.5 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Ribosomal_L7Ae PF01248.21 OAJ10661.1 - 3.6e-27 93.7 1.5 1.3e-26 91.9 1.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Phage_integrase PF00589.17 OAJ10661.1 - 8.4e-05 22.3 0.0 0.00017 21.2 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Ribosomal_S17 PF00366.15 OAJ10662.1 - 6.6e-31 106.1 0.7 1e-30 105.5 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 zf-C2H2_2 PF12756.2 OAJ10670.1 - 0.07 13.2 0.1 0.57 10.3 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Sec1 PF00995.18 OAJ10675.1 - 2.8e-132 442.2 0.0 4.1e-132 441.6 0.0 1.2 1 0 0 1 1 1 1 Sec1 family Aida_N PF08910.5 OAJ10676.1 - 6.3 7.0 12.4 0.04 14.1 1.4 2.6 3 0 0 3 3 3 0 Aida N-terminus Transposase_21 PF02992.9 OAJ10682.1 - 8.6e-10 38.0 0.0 1.3e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ10683.1 - 0.0011 18.3 0.1 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Collagen PF01391.13 OAJ10690.1 - 3.4e-48 161.0 305.8 1.8e-09 37.0 21.5 8.8 3 3 5 8 8 8 7 Collagen triple helix repeat (20 copies) AMP-binding PF00501.23 OAJ10691.1 - 4.9e-84 282.1 0.0 6.3e-84 281.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Activator-TraM PF11657.3 OAJ10695.1 - 0.11 11.9 0.1 0.21 11.0 0.1 1.5 1 1 0 1 1 1 0 Transcriptional activator TraM CAS_CSE1 PF03378.10 OAJ10705.1 - 1.9e-120 402.1 0.0 3.3e-120 401.3 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 OAJ10705.1 - 1.3e-117 392.4 0.0 2.3e-117 391.7 0.0 1.4 1 0 0 1 1 1 1 Cse1 ubiquitin PF00240.18 OAJ10711.1 - 9.1e-19 66.6 0.4 1.4e-18 66.0 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 OAJ10711.1 - 1.2e-13 50.4 5.7 2.3e-06 27.2 0.2 3.2 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.6 OAJ10711.1 - 2.3e-12 46.1 14.5 4.5e-12 45.2 10.0 1.5 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.3 OAJ10711.1 - 1.1e-07 31.4 0.5 1.9e-07 30.6 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 OAJ10711.1 - 0.00071 19.4 0.1 0.0015 18.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 OAJ10711.1 - 0.011 15.2 0.0 0.28 10.7 0.0 2.7 2 0 0 2 2 2 0 UBA-like domain DUF2407 PF10302.4 OAJ10711.1 - 0.049 13.8 0.0 0.088 13.0 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CSTF2_hinge PF14327.1 OAJ10711.1 - 0.2 11.7 6.4 1.7 8.7 4.3 2.3 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 RAP1 PF07218.6 OAJ10711.1 - 1.5 6.8 5.2 2 6.4 3.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PCI PF01399.22 OAJ10712.1 - 0.0085 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 PCI domain RVT_2 PF07727.9 OAJ10722.1 - 7.5e-68 228.1 0.0 1e-67 227.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10722.1 - 2.4e-22 79.2 0.1 1.3e-21 76.8 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ10722.1 - 1.2e-08 34.4 0.3 1.7e-07 30.7 0.0 2.5 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-CCHC PF00098.18 OAJ10722.1 - 1.9e-07 30.6 8.0 0.00021 21.0 1.0 2.6 2 0 0 2 2 2 2 Zinc knuckle UBN2 PF14223.1 OAJ10722.1 - 2.9e-05 23.8 0.1 7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAJ10722.1 - 9.4e-05 21.9 0.1 0.00022 20.7 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 OAJ10722.1 - 0.00087 18.7 0.1 0.012 15.0 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain DUF1820 PF08850.6 OAJ10722.1 - 0.055 13.5 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1820) Asp_protease_2 PF13650.1 OAJ10731.1 - 2.8e-05 24.5 0.0 7.2e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ10731.1 - 0.00018 21.2 0.0 0.00067 19.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ10731.1 - 0.0052 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease WD40 PF00400.27 OAJ10739.1 - 7e-21 73.2 2.9 2.8e-07 30.1 0.2 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 OAJ10739.1 - 0.0046 15.1 0.1 0.012 13.7 0.0 1.6 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Ras PF00071.17 OAJ10740.1 - 1.3e-53 180.6 0.0 1.5e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ10740.1 - 9.9e-16 58.3 0.0 1.3e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ10740.1 - 1.5e-06 27.5 0.0 2.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AhpC-TSA_2 PF13911.1 OAJ10749.1 - 5.5e-14 52.0 0.0 9.5e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 OAJ10749.1 - 2.1e-08 33.8 0.0 4.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAJ10749.1 - 4.5e-08 32.8 0.0 8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DUF899 PF05988.7 OAJ10749.1 - 0.058 12.8 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Sugarporin_N PF11471.3 OAJ10755.1 - 0.098 12.3 0.3 0.25 11.0 0.2 1.7 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension zf-RING_2 PF13639.1 OAJ10756.1 - 1.2e-10 40.9 5.3 5.4e-09 35.7 0.4 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ10756.1 - 1.1e-06 28.5 0.4 1.1e-06 28.5 0.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ10756.1 - 2e-05 24.2 2.7 5.5e-05 22.8 0.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 OAJ10756.1 - 2.5e-05 23.8 3.0 0.00038 20.0 0.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 OAJ10756.1 - 3.3e-05 23.8 0.7 0.00023 21.2 0.0 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 OAJ10756.1 - 0.00014 21.4 4.5 0.00023 20.7 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAJ10756.1 - 0.0038 16.9 0.3 0.0038 16.9 0.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING-like PF08746.6 OAJ10756.1 - 0.013 15.5 0.4 0.026 14.5 0.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-Apc11 PF12861.2 OAJ10756.1 - 0.034 13.9 0.2 0.034 13.9 0.2 1.6 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RAB3GAP2_N PF14655.1 OAJ10756.1 - 0.067 12.1 5.0 0.13 11.2 3.4 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Rad50_zn_hook PF04423.9 OAJ10756.1 - 0.075 12.5 2.3 0.58 9.6 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif FANCL_C PF11793.3 OAJ10756.1 - 0.3 11.0 7.8 0.31 11.0 2.3 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 OAJ10756.1 - 2.7 7.6 7.1 0.46 10.0 0.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.2 OAJ10756.1 - 3 7.9 7.8 0.3 11.1 1.1 2.1 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.1 OAJ10756.1 - 4 7.3 8.9 0.67 9.8 0.2 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 OAJ10756.1 - 4.2 6.9 6.9 0.28 10.6 0.8 1.9 2 0 0 2 2 2 0 P-11 zinc finger RVT_1 PF00078.22 OAJ10761.1 - 2.5e-13 49.8 0.0 6.3e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MMR_HSR1 PF01926.18 OAJ10769.1 - 3.9e-12 46.1 0.0 2.6e-11 43.4 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ10769.1 - 0.0009 18.5 0.1 0.0018 17.5 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 OAJ10769.1 - 0.0015 18.3 0.1 0.0055 16.5 0.1 2.0 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 OAJ10769.1 - 0.13 11.4 0.1 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SspB PF04386.8 OAJ10769.1 - 1.6 8.2 3.7 0.74 9.4 0.2 2.1 2 0 0 2 2 2 0 Stringent starvation protein B NPL4 PF05021.10 OAJ10770.1 - 9.8e-85 284.3 0.0 1.7e-82 277.0 0.0 3.3 2 1 0 2 2 2 1 NPL4 family zf-NPL4 PF05020.10 OAJ10770.1 - 5.9e-66 220.6 0.1 9.1e-66 220.0 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 OAJ10770.1 - 8.8e-05 22.7 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 UIM PF02809.15 OAJ10770.1 - 0.0065 15.9 0.6 0.02 14.4 0.4 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif zf-RanBP PF00641.13 OAJ10770.1 - 8.6 5.5 7.8 0.15 11.1 0.5 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others RVT_1 PF00078.22 OAJ10778.1 - 2.4e-17 62.9 0.0 4.5e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10778.1 - 8.8e-15 54.8 0.0 2.6e-14 53.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ10778.1 - 0.0015 18.9 0.1 0.0044 17.5 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ10778.1 - 0.044 13.7 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF3658 PF12395.3 OAJ10788.1 - 0.1 12.1 0.9 0.12 11.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function ATP-synt_E PF05680.7 OAJ10788.1 - 0.13 12.2 1.7 0.17 11.8 1.2 1.3 1 0 0 1 1 1 0 ATP synthase E chain Metal_resist PF13801.1 OAJ10788.1 - 0.45 10.5 7.6 0.52 10.3 5.3 1.1 1 0 0 1 1 1 0 Heavy-metal resistance RVT_2 PF07727.9 OAJ10789.1 - 8.4e-79 264.0 0.0 1.3e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10789.1 - 3.8e-20 72.1 0.0 1.8e-19 70.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ10789.1 - 2.3e-06 27.1 0.0 2.3e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain RVP PF00077.15 OAJ10789.1 - 0.0018 18.1 0.0 0.0051 16.7 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RdRP PF05183.7 OAJ10795.1 - 3.1e-148 495.0 0.0 4.3e-148 494.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Period_C PF12114.3 OAJ10795.1 - 0.34 10.5 0.3 0.57 9.7 0.2 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region MULE PF10551.4 OAJ10804.1 - 6.5e-07 29.4 0.1 1.3e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 OAJ10804.1 - 0.0001 21.7 0.1 0.00032 20.0 0.1 1.8 1 0 0 1 1 1 1 SWIM zinc finger CDRN PF05174.7 OAJ10804.1 - 0.0056 16.0 0.1 0.016 14.6 0.1 1.7 1 0 0 1 1 1 1 Cysteine-rich D. radiodurans N terminus zf-C4H2 PF10146.4 OAJ10804.1 - 0.11 12.5 0.4 0.21 11.5 0.2 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein RasGAP PF00616.14 OAJ10812.1 - 0.086 12.4 0.1 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase YL1 PF05764.8 OAJ10812.1 - 0.32 10.5 21.6 0.015 14.8 10.5 1.8 2 0 0 2 2 2 0 YL1 nuclear protein TSC22 PF01166.13 OAJ10812.1 - 0.5 10.3 4.7 0.13 12.2 0.5 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF3782 PF12644.2 OAJ10812.1 - 0.63 9.8 5.4 1.5 8.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) RVT_1 PF00078.22 OAJ10816.1 - 2.7e-24 85.7 0.0 4.9e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ10816.1 - 2.3e-17 62.6 0.2 5.6e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ10816.1 - 1.5e-06 28.3 0.6 4.2e-06 26.8 0.4 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 OAJ10818.1 - 0.00026 21.2 0.5 0.00059 20.1 0.4 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.19 OAJ10818.1 - 0.00027 21.3 0.0 0.00063 20.0 0.0 1.7 2 0 0 2 2 2 1 RNase H HypA PF01155.14 OAJ10818.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family CTD PF12815.2 OAJ10825.1 - 0.0018 18.6 13.1 0.11 12.8 9.1 2.1 1 1 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 UCH PF00443.24 OAJ10826.1 - 1.3e-80 270.4 0.0 2.5e-80 269.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ10826.1 - 9.4e-20 71.2 0.0 8.8e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 OAJ10826.1 - 7.8e-13 48.6 0.0 2e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 DUSP domain USP7_C2 PF14533.1 OAJ10826.1 - 0.0076 15.6 0.0 3 7.2 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin-specific protease C-terminal zf-FPG_IleRS PF06827.9 OAJ10826.1 - 0.1 12.2 0.9 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS CW_binding_1 PF01473.15 OAJ10826.1 - 0.12 12.5 1.9 0.31 11.2 0.6 2.1 2 0 0 2 2 2 0 Putative cell wall binding repeat Velvet PF11754.3 OAJ10834.1 - 3.1e-43 147.7 7.8 5.8e-31 107.6 0.0 3.3 3 0 0 3 3 3 2 Velvet factor ENTH PF01417.15 OAJ10835.1 - 4.4e-48 162.2 0.0 1.1e-47 161.0 0.0 1.7 1 0 0 1 1 1 1 ENTH domain UIM PF02809.15 OAJ10835.1 - 0.0029 17.0 9.0 0.042 13.4 0.7 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif ANTH PF07651.11 OAJ10835.1 - 0.0033 16.1 2.4 0.0033 16.1 1.7 2.5 2 1 0 2 2 2 1 ANTH domain DUF4192 PF13830.1 OAJ10835.1 - 2.6 7.5 8.6 4.3 6.8 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) LSM PF01423.17 OAJ10836.1 - 1.3e-17 63.1 0.1 1.5e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 OAJ10836.1 - 1.3e-06 28.2 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain EBP PF05241.7 OAJ10843.1 - 1.1e-05 24.5 5.7 2.1e-05 23.6 3.9 1.4 1 1 0 1 1 1 1 Emopamil binding protein eIF2A PF08662.6 OAJ10844.1 - 1.6e-81 272.6 0.1 4.7e-79 264.6 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 OAJ10844.1 - 0.0086 15.9 3.6 0.57 10.1 0.1 4.3 6 0 0 6 6 6 1 WD domain, G-beta repeat CDV3 PF15359.1 OAJ10844.1 - 0.013 15.5 2.2 0.013 15.5 1.5 3.6 2 1 1 4 4 4 0 Carnitine deficiency-associated protein 3 Proteasome_A_N PF10584.4 OAJ10844.1 - 2.1 7.7 4.4 31 4.0 0.0 3.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Pkinase PF00069.20 OAJ10845.1 - 7.9e-58 195.6 0.0 9.3e-58 195.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ10845.1 - 3.3e-20 72.2 0.0 4.6e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ10845.1 - 2.4e-07 30.7 0.4 1.7e-05 24.6 0.2 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAJ10845.1 - 0.0084 15.7 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 OAJ10845.1 - 0.02 13.9 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ10845.1 - 0.09 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like ThiF PF00899.16 OAJ10850.1 - 1.1e-42 145.1 0.0 1.9e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 OAJ10850.1 - 2.3e-27 94.3 0.1 4.5e-27 93.4 0.1 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 OAJ10850.1 - 3.9e-21 74.1 3.2 9.4e-21 72.9 2.2 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 OAJ10850.1 - 1.3e-05 25.2 0.2 0.00048 20.1 0.1 2.6 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 OAJ10850.1 - 0.00064 19.8 0.2 0.0025 17.9 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 OAJ10850.1 - 0.071 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 OAJ10850.1 - 0.11 12.9 0.1 0.37 11.2 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase P21-Arc PF04062.9 OAJ10857.1 - 1.2e-76 256.3 0.0 1.4e-76 256.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit vATP-synt_E PF01991.13 OAJ10858.1 - 8.1e-58 194.9 13.9 9.4e-58 194.7 9.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF3355 PF11835.3 OAJ10858.1 - 0.14 11.9 1.5 0.25 11.1 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3355) Pyr_redox_2 PF07992.9 OAJ10859.1 - 1.4e-19 70.8 0.0 2.4e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ10859.1 - 3.1e-13 49.9 0.1 1.8e-09 37.8 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 OAJ10859.1 - 2.1e-08 32.8 4.0 4.7e-05 22.3 0.9 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 OAJ10859.1 - 3.1e-07 30.4 3.1 1.1e-06 28.6 2.3 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 OAJ10859.1 - 3.5e-07 29.5 2.8 0.00033 20.2 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 OAJ10859.1 - 1.6e-06 27.1 3.9 0.0014 17.9 0.7 2.4 2 0 0 2 2 2 2 EF hand NAD_binding_7 PF13241.1 OAJ10859.1 - 0.0055 16.9 0.5 2.5 8.4 0.0 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding EF-hand_8 PF13833.1 OAJ10859.1 - 0.0099 15.4 5.1 1.4 8.6 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair Mito_fiss_reg PF05308.6 OAJ10859.1 - 0.078 12.3 1.8 0.14 11.5 1.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator SPARC_Ca_bdg PF10591.4 OAJ10859.1 - 0.12 12.3 1.8 1.2 9.1 0.2 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Rad60-SLD PF11976.3 OAJ10866.1 - 0.042 13.5 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 OAJ10866.1 - 0.075 12.4 0.0 0.35 10.3 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin family TP2 PF01254.13 OAJ10876.1 - 0.62 10.4 5.9 1.6 9.1 4.1 1.6 1 0 0 1 1 1 0 Nuclear transition protein 2 Med3 PF11593.3 OAJ10876.1 - 3.7 6.6 5.3 6.5 5.8 3.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RVT_1 PF00078.22 OAJ10877.1 - 9e-18 64.4 0.0 1.6e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10877.1 - 1.7e-10 41.0 0.0 3.1e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ10877.1 - 0.0052 17.2 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ10877.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.22 OAJ10883.1 - 1.1e-16 60.8 0.0 2.2e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10883.1 - 5.3e-13 49.1 0.0 1.6e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ10883.1 - 0.00026 21.4 0.0 0.00085 19.7 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ10883.1 - 0.024 14.5 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease dUTPase PF00692.14 OAJ10883.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 dUTPase Drc1-Sld2 PF11719.3 OAJ10890.1 - 1.7e-10 40.6 5.0 1.7e-10 40.6 3.4 5.3 1 1 1 3 3 3 1 DNA replication and checkpoint protein ALG3 PF05208.8 OAJ10891.1 - 6.3e-118 394.1 9.7 8.9e-118 393.7 6.7 1.2 1 0 0 1 1 1 1 ALG3 protein PBP PF01161.15 OAJ10892.1 - 2.2e-14 53.5 0.1 3.5e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FAM72 PF14976.1 OAJ10899.1 - 1.8e-21 76.5 0.2 5.3e-21 75.0 0.1 1.7 2 0 0 2 2 2 1 FAM72 protein GST_N_3 PF13417.1 OAJ10900.1 - 3.8e-16 59.0 0.0 7.7e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAJ10900.1 - 1.2e-13 50.9 0.0 2.7e-13 49.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ10900.1 - 8.7e-12 44.8 0.0 3.7e-11 42.8 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ10900.1 - 9e-10 38.4 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ10900.1 - 9.5e-09 35.6 0.1 1.6e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ10900.1 - 1.1e-05 25.2 0.0 2.8e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Retrotrans_gag PF03732.12 OAJ10908.1 - 2.5e-12 46.6 0.2 1.4e-11 44.2 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF2205 PF10224.4 OAJ10908.1 - 0.0064 16.0 1.3 0.014 14.9 0.9 1.5 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) TSC22 PF01166.13 OAJ10908.1 - 0.038 13.9 1.0 0.12 12.3 0.2 2.2 3 0 0 3 3 3 0 TSC-22/dip/bun family RVT_1 PF00078.22 OAJ10909.1 - 4.7e-26 91.4 0.1 1.1e-25 90.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10909.1 - 1.3e-21 76.8 0.0 4.3e-21 75.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 OAJ10909.1 - 4.1e-08 32.7 0.0 1.2e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 OAJ10909.1 - 2.2e-05 24.8 0.0 5.9e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ10909.1 - 7.1e-05 22.5 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease FHA PF00498.21 OAJ10917.1 - 0.0035 17.4 0.1 0.0068 16.4 0.1 1.5 1 0 0 1 1 1 1 FHA domain FHA PF00498.21 OAJ10918.1 - 0.071 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 FHA domain zf-HIT PF04438.11 OAJ10928.1 - 7.8e-08 31.8 9.6 1.4e-07 31.0 6.6 1.3 1 0 0 1 1 1 1 HIT zinc finger TRAM_LAG1_CLN8 PF03798.11 OAJ10929.1 - 6.3e-18 65.0 4.8 7.6e-18 64.7 3.3 1.0 1 0 0 1 1 1 1 TLC domain Aldose_epim PF01263.15 OAJ10930.1 - 3e-57 194.0 0.1 4.9e-57 193.3 0.1 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Helitron_like_N PF14214.1 OAJ10940.1 - 2.4e-34 118.7 0.0 3.8e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus HMG-CoA_red PF00368.13 OAJ10941.1 - 0.083 11.5 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase PIF1 PF05970.9 OAJ10942.1 - 1.4e-51 175.5 0.0 4.1e-51 174.0 0.0 1.7 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ10942.1 - 3.2e-08 33.3 0.1 7.5e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 OAJ10942.1 - 0.00077 19.0 0.6 1.1 8.7 0.0 2.9 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 OAJ10942.1 - 0.0055 16.3 0.0 0.0099 15.5 0.0 1.4 1 0 0 1 1 1 1 Helicase AAA_19 PF13245.1 OAJ10942.1 - 0.0061 16.2 0.1 0.015 15.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 OAJ10942.1 - 0.012 15.7 0.0 0.036 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 OAJ10942.1 - 0.026 13.2 0.1 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_5 PF07728.9 OAJ10942.1 - 0.063 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Herpes_Helicase PF02689.9 OAJ10942.1 - 0.066 10.9 0.0 0.79 7.3 0.0 2.2 3 0 0 3 3 3 0 Helicase UvrD_C_2 PF13538.1 OAJ10942.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain RPA_C PF08784.6 OAJ10942.1 - 0.17 12.2 0.0 31 5.0 0.0 2.5 2 0 0 2 2 2 0 Replication protein A C terminal Dimer_Tnp_hAT PF05699.9 OAJ10950.1 - 2.1e-12 46.4 0.0 5.5e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3279 PF11682.3 OAJ10950.1 - 0.023 14.2 0.1 0.051 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) zf-BED PF02892.10 OAJ10950.1 - 0.079 12.7 3.5 0.14 11.9 1.1 2.3 2 0 0 2 2 2 0 BED zinc finger DUF4413 PF14372.1 OAJ10950.1 - 0.1 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Pkinase PF00069.20 OAJ10951.1 - 5.1e-40 137.2 0.0 6.2e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ10951.1 - 4.4e-17 62.0 0.0 7e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ10951.1 - 2.6e-06 26.6 0.0 4.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ10951.1 - 0.00069 18.7 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Acyl-CoA_dh_1 PF00441.19 OAJ10960.1 - 1.1e-31 109.9 0.2 1.8e-31 109.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ10960.1 - 5.3e-16 57.8 0.2 1.3e-15 56.6 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 OAJ10960.1 - 6.2e-16 57.9 0.0 1.5e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 OAJ10960.1 - 4.6e-12 46.5 0.5 2.5e-11 44.1 0.0 2.5 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAJ10960.1 - 9.4e-05 22.6 0.1 0.00017 21.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.11 OAJ10968.1 - 2.1e-06 26.6 1.3 2.8e-06 26.2 0.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Chorein_N PF12624.2 OAJ10970.1 - 1.7e-33 114.6 0.0 4.1e-33 113.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter adh_short_C2 PF13561.1 OAJ10970.1 - 2.3e-10 40.6 0.0 5.3e-10 39.4 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ10970.1 - 6.3e-08 32.7 1.8 0.0003 20.7 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 OAJ10970.1 - 2.1e-05 24.2 0.4 0.0021 17.7 0.0 2.4 2 0 0 2 2 2 2 KR domain SelP_N PF04592.9 OAJ10980.1 - 0.29 10.4 4.2 0.3 10.4 2.9 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Vfa1 PF08432.5 OAJ10980.1 - 0.31 11.0 18.5 0.34 10.9 12.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1897 PF09005.5 OAJ10980.1 - 0.59 9.6 3.7 2.5 7.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1897) FYDLN_acid PF09538.5 OAJ10980.1 - 4 8.0 36.6 4.6 7.8 25.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Rhabdo_ncap PF00945.13 OAJ10980.1 - 4.3 5.8 10.4 5.2 5.5 7.2 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF3449 PF11931.3 OAJ10980.1 - 5.7 6.4 9.2 6.5 6.2 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) CDC45 PF02724.9 OAJ10980.1 - 6.9 4.5 26.8 7.5 4.4 18.6 1.0 1 0 0 1 1 1 0 CDC45-like protein UBN2 PF14223.1 OAJ10987.1 - 4.5e-05 23.2 0.0 0.00012 21.8 0.0 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ10987.1 - 7.2e-05 22.5 2.2 0.00017 21.3 1.5 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ10987.1 - 0.083 12.5 0.7 0.17 11.5 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 OAJ10987.1 - 0.23 10.9 2.1 0.26 10.7 0.1 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RVT_2 PF07727.9 OAJ10988.1 - 9.8e-87 289.9 0.0 1.3e-86 289.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAJ10988.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) HHH_8 PF14716.1 OAJ10989.1 - 0.095 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain DSS1_SEM1 PF05160.8 OAJ10997.1 - 8.3e-19 67.1 9.3 3.7e-12 45.8 2.2 2.2 2 0 0 2 2 2 2 DSS1/SEM1 family Stm1_N PF09598.5 OAJ10997.1 - 1.2 9.9 7.4 1.3 9.8 0.0 3.0 3 0 0 3 3 3 0 Stm1 Med15 PF09606.5 OAJ10998.1 - 0.0017 16.6 25.3 0.0023 16.2 17.5 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal SWIRM PF04433.12 OAJ10999.1 - 2e-16 59.8 0.0 7.9e-16 57.9 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 OAJ10999.1 - 3.3e-10 39.8 0.0 1.1e-09 38.1 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 OAJ10999.1 - 2e-09 36.8 7.2 3.4e-09 36.0 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 OAJ10999.1 - 3.2e-06 27.1 0.0 1e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain RNA_pol_Rpb4 PF03874.11 OAJ10999.1 - 0.14 12.1 0.5 0.3 11.0 0.4 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb4 RAP1 PF07218.6 OAJ11008.1 - 0.55 8.2 5.4 0.56 8.2 3.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Spt5_N PF11942.3 OAJ11009.1 - 0.015 15.9 14.1 0.024 15.2 9.8 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Spore_coat_CotO PF14153.1 OAJ11009.1 - 0.017 14.5 7.6 0.018 14.5 5.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Ycf1 PF05758.7 OAJ11009.1 - 0.039 11.6 4.1 0.036 11.8 2.8 1.0 1 0 0 1 1 1 0 Ycf1 Nop14 PF04147.7 OAJ11009.1 - 0.04 11.8 10.9 0.05 11.5 7.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3513 PF12026.3 OAJ11009.1 - 0.11 12.0 8.0 0.15 11.6 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) eIF-3_zeta PF05091.7 OAJ11009.1 - 0.15 10.6 8.6 0.17 10.4 6.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CDC45 PF02724.9 OAJ11009.1 - 0.54 8.2 13.2 0.65 7.9 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SUFU_C PF12470.3 OAJ11009.1 - 0.75 9.3 4.4 0.74 9.3 2.5 1.3 1 1 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain PAT1 PF09770.4 OAJ11009.1 - 2.7 6.1 28.7 3.2 5.8 19.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 OAJ11009.1 - 2.7 7.7 11.8 4 7.2 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ebola_NP PF05505.7 OAJ11009.1 - 2.8 5.8 11.1 3.1 5.7 7.7 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DUF605 PF04652.11 OAJ11009.1 - 3.3 7.0 22.6 4.1 6.6 15.7 1.1 1 0 0 1 1 1 0 Vta1 like MCPVI PF02993.9 OAJ11009.1 - 5.2 7.1 20.5 7.5 6.6 14.1 1.4 1 1 0 1 1 1 0 Minor capsid protein VI NARP1 PF12569.3 OAJ11009.1 - 5.4 5.6 10.7 6.8 5.3 7.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Menin PF05053.8 OAJ11009.1 - 6.4 4.8 10.8 6.7 4.7 7.5 1.0 1 0 0 1 1 1 0 Menin VID27 PF08553.5 OAJ11010.1 - 2.7e-15 55.7 5.9 1.2e-09 37.0 1.8 2.0 2 0 0 2 2 2 2 VID27 cytoplasmic protein PRP1_N PF06424.7 OAJ11010.1 - 0.38 11.0 3.7 0.31 11.3 1.7 1.5 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Nop14 PF04147.7 OAJ11010.1 - 2.9 5.6 6.7 3 5.6 4.7 1.0 1 0 0 1 1 1 0 Nop14-like family CAF-1_p150 PF11600.3 OAJ11018.1 - 6 6.1 57.0 0.047 13.0 25.1 2.5 2 1 1 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal HAD PF12710.2 OAJ11019.1 - 0.057 13.5 0.0 0.057 13.5 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2066 PF09839.4 OAJ11020.1 - 0.15 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) RVT_1 PF00078.22 OAJ11031.1 - 1.1e-16 60.9 0.1 2e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ11031.1 - 4.4e-12 46.1 0.0 8.6e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ11031.1 - 0.00042 20.7 0.0 0.0014 19.0 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ11031.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease dUTPase PF00692.14 OAJ11031.1 - 0.2 11.1 0.0 0.45 9.9 0.0 1.5 1 0 0 1 1 1 0 dUTPase DUF2360 PF10152.4 OAJ11031.1 - 5.3 7.3 9.6 35 4.6 1.0 3.6 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) MTP18 PF10558.4 OAJ11041.1 - 1.3e-24 86.7 0.0 2.6e-24 85.8 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial 18 KDa protein (MTP18) DUF3464 PF11947.3 OAJ11041.1 - 0.016 14.6 0.1 0.016 14.6 0.1 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3464) A1_Propeptide PF07966.7 OAJ11052.1 - 0.12 12.1 0.4 0.2 11.4 0.3 1.3 1 0 0 1 1 1 0 A1 Propeptide MULE PF10551.4 OAJ11053.1 - 2.4e-10 40.4 0.1 4.2e-09 36.4 0.0 2.8 2 1 1 3 3 3 1 MULE transposase domain DDE_Tnp_IS240 PF13610.1 OAJ11053.1 - 0.015 15.2 0.0 6.3 6.7 0.1 2.6 1 1 0 2 2 2 0 DDE domain Septin PF00735.13 OAJ11054.1 - 1e-08 34.5 0.0 1.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Septin Sugar_tr PF00083.19 OAJ11060.1 - 2.8e-99 332.7 20.4 3.3e-99 332.4 14.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ11060.1 - 1.6e-24 86.2 24.8 1.9e-23 82.7 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FYDLN_acid PF09538.5 OAJ11060.1 - 4.8 7.8 11.9 0.47 11.0 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Dimer_Tnp_hAT PF05699.9 OAJ11070.1 - 5.9e-05 22.6 0.0 0.00017 21.1 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DEAD PF00270.24 OAJ11079.1 - 2e-09 37.1 0.0 3.8e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ11079.1 - 1.6e-08 34.2 0.0 2.1e-07 30.7 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ11079.1 - 0.0013 18.5 0.1 0.0046 16.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF87 PF01935.12 OAJ11079.1 - 0.058 13.2 1.8 2 8.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 DUF3886 PF13025.1 OAJ11079.1 - 0.38 10.7 10.7 0.75 9.7 4.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) MitMem_reg PF13012.1 OAJ11089.1 - 2e-33 114.9 0.1 5.7e-33 113.4 0.0 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 OAJ11089.1 - 3e-27 94.6 0.0 4.9e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Pkinase PF00069.20 OAJ11090.1 - 3e-59 200.3 0.0 4.2e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ11090.1 - 3.9e-31 108.0 0.0 5.2e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ11090.1 - 0.0053 15.7 0.0 0.008 15.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like rve PF00665.21 OAJ11098.1 - 2.9e-14 53.1 0.0 6.2e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ11098.1 - 3.6e-09 36.2 0.0 1.2e-05 24.8 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Phospholip_B PF04916.8 OAJ11098.1 - 0.37 8.8 0.0 0.59 8.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase B Myb_DNA-bind_3 PF12776.2 OAJ11099.1 - 2.1e-05 25.0 0.6 4.2e-05 24.1 0.1 1.7 2 0 0 2 2 1 1 Myb/SANT-like DNA-binding domain Trypan_PARP PF05887.6 OAJ11099.1 - 0.012 15.3 5.6 0.021 14.6 3.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Myc_N PF01056.13 OAJ11099.1 - 0.023 13.8 2.7 0.03 13.4 1.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region PBP1_TM PF14812.1 OAJ11099.1 - 0.15 12.4 5.6 0.34 11.2 3.9 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 OAJ11099.1 - 0.15 12.3 6.6 0.23 11.7 4.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 OAJ11099.1 - 0.25 10.8 4.2 0.33 10.4 2.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 OAJ11099.1 - 0.27 10.4 3.0 0.33 10.1 2.1 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 OAJ11099.1 - 0.38 8.7 2.9 0.36 8.8 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.1 OAJ11099.1 - 0.47 10.6 9.0 0.27 11.3 4.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Atrophin-1 PF03154.10 OAJ11099.1 - 0.62 8.1 4.5 0.73 7.9 3.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family TT_ORF2 PF02957.10 OAJ11099.1 - 1.4 9.6 5.2 2.8 8.6 3.6 1.6 1 0 0 1 1 1 0 TT viral ORF2 An_peroxidase PF03098.10 OAJ11106.1 - 1.5e-18 66.4 0.0 2.1e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 OAJ11106.1 - 3.1e-13 49.0 0.0 7.9e-13 47.7 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 GMC_oxred_N PF00732.14 OAJ11107.1 - 7.4e-62 209.1 0.0 1e-61 208.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ11107.1 - 2.1e-30 105.9 0.0 4.8e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAJ11107.1 - 2.5e-07 29.9 0.9 6.5e-06 25.2 0.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ11107.1 - 6.2e-06 25.3 0.1 0.00081 18.3 0.2 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 OAJ11107.1 - 2.5e-05 24.2 0.1 9.4e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAJ11107.1 - 2.5e-05 24.4 0.0 0.23 11.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAJ11107.1 - 0.00038 19.4 0.2 0.00055 18.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 OAJ11107.1 - 0.0011 17.5 0.6 0.0042 15.6 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 OAJ11107.1 - 0.0084 15.9 0.3 0.044 13.6 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SURF4 PF02077.10 OAJ11115.1 - 4.5e-95 318.0 3.2 5.1e-95 317.8 2.2 1.0 1 0 0 1 1 1 1 SURF4 family Trp_oprn_chp PF09534.5 OAJ11115.1 - 1.8 8.1 4.7 1 8.9 0.7 2.2 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) HR_lesion PF05514.6 OAJ11115.1 - 10 5.9 8.7 2.1 8.2 0.9 3.1 3 1 1 4 4 4 0 HR-like lesion-inducing Citrate_synt PF00285.16 OAJ11116.1 - 2.7e-18 65.8 0.1 1.3e-15 56.9 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 OAJ11116.1 - 1.8e-14 53.5 0.1 5e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 OAJ11116.1 - 3.2e-11 43.5 0.0 8.3e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 OAJ11116.1 - 1.3e-06 27.9 0.0 2.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 OAJ11116.1 - 9.2e-05 22.0 0.0 0.0003 20.3 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.1 OAJ11116.1 - 0.0054 15.9 0.0 0.022 13.9 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain HTH_32 PF13565.1 OAJ11127.1 - 0.083 13.6 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain TerB PF05099.8 OAJ11127.1 - 0.099 12.3 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TerB SurE PF01975.12 OAJ11137.1 - 8.2e-33 113.3 1.1 2.1e-32 112.0 0.0 2.1 1 1 1 2 2 2 1 Survival protein SurE ABC2_membrane PF01061.19 OAJ11138.1 - 4.9e-83 277.4 59.3 6.5e-43 146.3 17.0 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 OAJ11138.1 - 3e-39 134.4 0.0 7.9e-19 68.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 OAJ11138.1 - 9.9e-23 79.7 2.9 8.8e-20 70.2 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter AAA_17 PF13207.1 OAJ11138.1 - 4.8e-07 30.6 0.0 0.012 16.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAJ11138.1 - 5.4e-07 29.1 0.1 0.0021 17.4 0.1 3.4 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 OAJ11138.1 - 1.7e-06 27.9 0.7 0.049 13.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 OAJ11138.1 - 3.7e-06 26.3 0.0 0.00053 19.2 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 OAJ11138.1 - 1.4e-05 24.4 0.5 0.008 15.6 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 OAJ11138.1 - 2.1e-05 23.7 57.3 0.0025 16.9 17.4 3.8 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 OAJ11138.1 - 5.2e-05 23.3 0.0 0.037 14.0 0.0 2.6 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAJ11138.1 - 0.0001 22.4 0.0 0.43 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 OAJ11138.1 - 0.00012 21.6 0.0 0.0076 15.7 0.0 2.5 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 OAJ11138.1 - 0.0002 20.5 0.0 0.013 14.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 OAJ11138.1 - 0.00072 19.5 1.2 0.076 12.9 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 OAJ11138.1 - 0.0017 17.8 0.0 0.38 10.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 OAJ11138.1 - 0.0019 18.5 3.7 0.26 11.6 0.0 3.6 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 OAJ11138.1 - 0.011 15.3 0.4 2.9 7.5 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 OAJ11138.1 - 0.017 14.8 0.8 6.2 6.6 0.1 3.1 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 OAJ11138.1 - 0.029 14.3 0.1 0.088 12.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain DUF1825 PF08855.5 OAJ11138.1 - 0.041 13.8 3.0 0.85 9.6 0.0 3.0 4 0 0 4 4 2 0 Domain of unknown function (DUF1825) AAA_10 PF12846.2 OAJ11138.1 - 0.048 13.0 0.1 2.8 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 OAJ11138.1 - 0.056 13.0 0.5 2.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 OAJ11138.1 - 0.059 13.2 0.0 0.87 9.5 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 OAJ11138.1 - 0.09 11.8 0.3 8.9 5.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.24 OAJ11138.1 - 0.11 12.6 0.2 21 5.3 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 OAJ11138.1 - 0.11 12.6 0.0 12 6.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.1 OAJ11138.1 - 0.12 11.9 0.1 4.8 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 OAJ11138.1 - 0.12 12.3 0.0 22 5.0 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_trans_N PF14510.1 OAJ11138.1 - 0.19 11.8 0.0 0.44 10.6 0.0 1.7 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal Miro PF08477.8 OAJ11138.1 - 0.2 12.1 0.1 18 5.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_15 PF13175.1 OAJ11138.1 - 0.23 10.4 0.0 8.3 5.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 OAJ11138.1 - 0.38 11.0 1.7 0.87 9.8 0.1 2.4 3 0 0 3 3 1 0 AAA domain NB-ARC PF00931.17 OAJ11138.1 - 0.47 9.2 0.8 26 3.5 0.1 2.8 3 0 0 3 3 3 0 NB-ARC domain T2SE PF00437.15 OAJ11138.1 - 0.6 8.9 0.5 4.5 6.0 0.0 2.3 3 0 0 3 3 2 0 Type II/IV secretion system protein zf-CCHC PF00098.18 OAJ11147.1 - 6.1e-07 29.0 0.7 9.4e-07 28.4 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ11147.1 - 0.0012 18.3 0.5 0.0025 17.2 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Orbi_NS3 PF01616.11 OAJ11148.1 - 0.004 16.1 2.5 0.18 10.7 0.1 2.5 2 0 0 2 2 2 1 Orbivirus NS3 IncA PF04156.9 OAJ11148.1 - 0.044 13.3 25.5 0.081 12.5 0.6 2.6 2 1 0 2 2 2 0 IncA protein TEBP_beta PF07404.6 OAJ11148.1 - 0.11 11.5 4.5 0.2 10.7 3.1 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) TBPIP PF07106.8 OAJ11148.1 - 0.25 10.8 15.3 1.1 8.7 0.5 3.2 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 OAJ11148.1 - 0.29 11.3 3.8 2.5 8.4 0.1 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Vfa1 PF08432.5 OAJ11148.1 - 1.9 8.4 11.3 4.6 7.2 0.1 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.1 OAJ11148.1 - 2.1 7.2 22.2 1.9 7.3 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FH2 PF02181.18 OAJ11148.1 - 2.3 6.9 7.1 0.19 10.5 0.9 1.9 2 1 1 3 3 3 0 Formin Homology 2 Domain DUF972 PF06156.8 OAJ11148.1 - 2.7 8.3 17.2 9.4 6.6 1.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Prefoldin_2 PF01920.15 OAJ11148.1 - 3.6 7.3 13.7 5.8 6.7 0.2 3.2 3 0 0 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.5 OAJ11148.1 - 3.6 7.6 7.9 25 4.9 3.5 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DivIVA PF05103.8 OAJ11148.1 - 4.2 7.4 23.3 0.42 10.6 4.9 3.2 2 1 1 3 3 3 0 DivIVA protein Latarcin PF10279.4 OAJ11148.1 - 4.7 7.4 7.0 4.7 7.4 0.3 2.5 2 0 0 2 2 2 0 Latarcin precursor TMF_DNA_bd PF12329.3 OAJ11148.1 - 5.1 6.9 21.9 1.2 8.9 1.4 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 OAJ11148.1 - 7.3 5.4 20.9 5.5 5.8 10.2 2.4 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Phage_GP20 PF06810.6 OAJ11148.1 - 8 5.8 16.5 0.81 9.1 0.9 3.2 2 1 1 3 3 3 0 Phage minor structural protein GP20 HALZ PF02183.13 OAJ11148.1 - 8.9 6.1 7.4 11 5.7 0.9 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Seryl_tRNA_N PF02403.17 OAJ11148.1 - 9 6.3 16.0 9 6.3 1.0 3.1 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 OAJ11148.1 - 9.6 5.7 20.8 0.39 10.2 0.6 3.3 3 0 0 3 3 3 0 Septum formation initiator Transposase_21 PF02992.9 OAJ11160.1 - 5.8e-05 22.2 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 GldM_N PF12081.3 OAJ11160.1 - 0.051 13.0 0.1 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 GldM N-terminal domain Med4 PF10018.4 OAJ11160.1 - 0.12 11.7 1.7 0.23 10.8 1.2 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 zf-C2H2_2 PF12756.2 OAJ11160.1 - 0.12 12.4 0.5 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF3886 PF13025.1 OAJ11160.1 - 1.7 8.6 5.2 0.43 10.5 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) zf-C2H2_2 PF12756.2 OAJ11161.1 - 0.096 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Mito_carr PF00153.22 OAJ11171.1 - 3.7e-65 215.6 4.8 7e-24 83.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NMO PF03060.10 OAJ11172.1 - 9.1e-70 235.4 3.6 1.1e-69 235.1 2.5 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 OAJ11172.1 - 8.5e-05 21.5 2.6 0.00016 20.6 1.8 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 OAJ11172.1 - 0.00018 20.5 4.6 0.0012 17.7 3.2 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain IF2_N PF04760.10 OAJ11172.1 - 0.025 14.2 0.0 0.071 12.7 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Tim17 PF02466.14 OAJ11173.1 - 3.9e-14 52.8 13.1 5.4e-14 52.3 9.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family FAA_hydrolase PF01557.13 OAJ11174.1 - 5.9e-54 182.8 0.0 7.7e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF4218 PF13960.1 OAJ11189.1 - 0.0023 17.3 0.1 0.0023 17.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.9 OAJ11189.1 - 0.0032 16.5 0.0 0.0046 16.0 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 PIF1 PF05970.9 OAJ11206.1 - 1.6e-21 76.7 0.0 3.7e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ11206.1 - 1.8e-12 47.2 2.1 1e-11 44.8 0.0 2.7 3 1 0 4 4 4 1 AAA domain Helitron_like_N PF14214.1 OAJ11206.1 - 4.7e-07 29.7 0.8 8.3e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAJ11206.1 - 3.6e-06 26.6 2.2 6.4e-06 25.8 0.1 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 OAJ11206.1 - 0.0031 17.5 0.0 0.018 15.0 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 OAJ11206.1 - 0.052 13.2 0.4 1.3 8.7 0.1 3.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 OAJ11206.1 - 0.11 11.9 0.0 0.43 10.0 0.0 2.0 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 OAJ11206.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 OAJ11206.1 - 0.15 11.9 0.0 0.47 10.3 0.0 1.8 1 0 0 1 1 1 0 Torsin DDE_1 PF03184.14 OAJ11213.1 - 4.2e-34 117.5 0.1 9.5e-34 116.4 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAJ11213.1 - 5.6e-09 35.6 0.0 8.5e-08 31.9 0.0 2.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain VASP_tetra PF08776.6 OAJ11213.1 - 0.07 12.4 0.8 0.16 11.3 0.6 1.6 1 0 0 1 1 1 0 VASP tetramerisation domain Nop14 PF04147.7 OAJ11222.1 - 0.68 7.7 2.3 1.3 6.8 1.6 1.3 1 0 0 1 1 1 0 Nop14-like family CRAL_TRIO_N PF03765.10 OAJ11228.1 - 8e-14 51.5 0.5 1.7e-13 50.4 0.3 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CdCA1 PF10563.4 OAJ11228.1 - 0.08 12.4 0.3 0.31 10.4 0.1 1.8 2 0 0 2 2 2 0 Cadmium carbonic anhydrase repeat adh_short PF00106.20 OAJ11234.1 - 4e-23 82.1 0.0 6.1e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ11234.1 - 2.8e-06 27.3 0.0 4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ11234.1 - 5.9e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAJ11234.1 - 0.0046 16.9 0.0 0.0078 16.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAJ11234.1 - 0.05 13.0 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2975 PF11188.3 OAJ11235.1 - 8.4 6.1 9.0 1.2 8.8 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) DUF1768 PF08719.6 OAJ11236.1 - 9.6e-12 44.9 1.4 1.5e-11 44.2 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) UPF0167 PF03691.9 OAJ11236.1 - 0.03 13.7 0.3 0.048 13.0 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) PPR_2 PF13041.1 OAJ11245.1 - 1.2e-27 95.6 0.0 1.8e-07 31.0 0.0 9.3 7 2 3 10 10 10 4 PPR repeat family PPR_3 PF13812.1 OAJ11245.1 - 3.6e-25 86.0 27.3 0.00034 20.6 0.0 15.6 17 0 0 17 17 17 6 Pentatricopeptide repeat domain PPR PF01535.15 OAJ11245.1 - 7.4e-21 72.6 11.7 0.014 15.3 0.0 11.7 14 0 0 14 14 14 6 PPR repeat PPR_1 PF12854.2 OAJ11245.1 - 1.4e-10 40.4 0.0 8.2 5.9 0.0 8.9 9 0 0 9 9 9 3 PPR repeat TPR_16 PF13432.1 OAJ11245.1 - 0.03 15.0 0.0 0.03 15.0 0.0 6.1 7 1 1 8 8 8 0 Tetratricopeptide repeat Ferritin-like PF12902.2 OAJ11245.1 - 0.035 13.7 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Ferritin-like TPR_19 PF14559.1 OAJ11245.1 - 0.053 13.8 4.5 0.48 10.8 0.0 4.7 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ11245.1 - 0.12 13.0 0.1 0.12 13.0 0.1 8.2 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ11245.1 - 0.27 11.1 9.8 1.6 8.7 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat DLIC PF05783.6 OAJ11246.1 - 1.8e-41 142.3 4.6 7.1e-27 94.2 0.0 5.6 4 2 1 5 5 5 4 Dynein light intermediate chain (DLIC) MCM PF00493.18 OAJ11246.1 - 5.2e-05 22.2 0.1 0.0001 21.2 0.0 1.5 2 0 0 2 2 2 1 MCM2/3/5 family AAA_16 PF13191.1 OAJ11246.1 - 0.0029 17.6 0.3 0.021 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.22 OAJ11246.1 - 0.004 16.6 0.0 2.2 7.6 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 OAJ11246.1 - 0.0047 16.3 0.1 1.4 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 OAJ11246.1 - 0.068 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 OAJ11246.1 - 0.072 13.5 0.4 1.4 9.4 0.0 2.8 3 1 1 4 4 4 0 Miro-like protein AAA_28 PF13521.1 OAJ11246.1 - 0.073 13.0 0.3 0.19 11.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 OAJ11246.1 - 0.14 12.9 0.0 0.45 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Cellulase PF00150.13 OAJ11255.1 - 6.9e-13 48.4 8.9 2.1e-12 46.8 6.2 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) V-SNARE_C PF12352.3 OAJ11256.1 - 2.7e-13 49.7 0.3 6.3e-13 48.5 0.2 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 OAJ11256.1 - 3.7e-06 26.5 0.0 7.4e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Sec20 RVT_1 PF00078.22 OAJ11257.1 - 6.3e-25 87.7 0.0 8.6e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GTP_EFTU PF00009.22 OAJ11266.1 - 7.3e-33 113.5 0.1 3.7e-25 88.4 0.5 3.0 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain IF-2 PF11987.3 OAJ11266.1 - 1e-20 73.6 0.0 1.8e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 OAJ11266.1 - 9.2e-06 25.5 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 OAJ11266.1 - 0.0015 18.5 2.1 0.97 9.5 0.3 2.8 2 0 0 2 2 2 2 Elongation factor Tu domain 2 SRPRB PF09439.5 OAJ11266.1 - 0.0052 16.0 0.0 0.051 12.7 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit IF2_N PF04760.10 OAJ11266.1 - 0.0099 15.5 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Miro PF08477.8 OAJ11266.1 - 0.043 14.3 0.0 0.099 13.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 OAJ11266.1 - 0.18 11.0 0.0 6 6.1 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B HLH PF00010.21 OAJ11267.1 - 9.4e-10 38.0 0.2 1.8e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UcrQ PF02939.11 OAJ11278.1 - 5.6e-19 67.7 4.2 7e-19 67.4 2.9 1.1 1 0 0 1 1 1 1 UcrQ family UQ_con PF00179.21 OAJ11279.1 - 4e-22 78.1 0.0 4.7e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ11279.1 - 0.017 14.8 0.0 0.034 13.9 0.0 1.5 1 1 1 2 2 2 0 Prokaryotic E2 family B MCM PF00493.18 OAJ11292.1 - 1.7e-139 464.2 0.0 2.3e-139 463.8 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 OAJ11292.1 - 2.1e-32 112.2 30.3 2.1e-32 112.2 21.0 2.2 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 OAJ11292.1 - 1.9e-18 67.0 0.1 6.5e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 OAJ11292.1 - 2.1e-08 33.5 0.0 7.8e-07 28.4 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 OAJ11292.1 - 4.1e-06 26.5 0.0 9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 OAJ11292.1 - 0.00044 19.8 0.0 0.0039 16.8 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAJ11292.1 - 0.013 14.9 0.0 0.099 12.1 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain DNA_gyraseB_C PF00986.16 OAJ11292.1 - 0.033 13.9 0.3 2.4 7.9 0.0 3.1 3 0 0 3 3 3 0 DNA gyrase B subunit, carboxyl terminus AAA PF00004.24 OAJ11292.1 - 0.11 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zn_ribbon_2 PF12674.2 OAJ11292.1 - 0.16 12.2 0.3 0.42 10.9 0.2 1.6 1 0 0 1 1 1 0 Putative zinc ribbon domain Septin PF00735.13 OAJ11293.1 - 4.6e-43 147.2 0.1 2e-15 56.5 0.0 4.7 5 0 0 5 5 5 4 Septin TFIIA PF03153.8 OAJ11293.1 - 0.00013 22.0 15.4 0.00013 22.0 10.7 3.3 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit GTP_EFTU PF00009.22 OAJ11293.1 - 0.033 13.6 0.0 8.5 5.7 0.0 3.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Nop25 PF09805.4 OAJ11293.1 - 0.9 9.6 45.9 1.2 9.2 25.5 2.6 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Dynamin_N PF00350.18 OAJ11293.1 - 2.3 7.9 12.4 1.8 8.3 0.0 3.7 4 0 0 4 4 4 0 Dynamin family RRN3 PF05327.6 OAJ11293.1 - 3.4 5.6 12.5 5.7 4.9 8.6 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 rve PF00665.21 OAJ11301.1 - 2.8e-17 62.9 0.0 3.8e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain FHA PF00498.21 OAJ11303.1 - 0.027 14.5 0.0 0.086 12.9 0.0 1.9 2 0 0 2 2 2 0 FHA domain RVT_1 PF00078.22 OAJ11308.1 - 1.2e-16 60.7 0.0 2.2e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ11308.1 - 6.1e-12 45.7 0.0 1.3e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ11308.1 - 0.00011 22.6 0.0 0.00029 21.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ11308.1 - 0.0018 18.1 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 OAJ11308.1 - 0.0038 17.2 0.4 0.0097 15.9 0.3 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 OAJ11308.1 - 0.0056 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Dus PF01207.12 OAJ11318.1 - 3.8e-44 150.7 0.0 2.2e-24 85.8 0.0 3.1 3 0 0 3 3 3 3 Dihydrouridine synthase (Dus) DUF3752 PF12572.3 OAJ11318.1 - 0.015 15.3 0.3 0.026 14.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Mito_carr PF00153.22 OAJ11319.1 - 4e-72 238.0 1.5 2.2e-26 91.3 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2457 PF10446.4 OAJ11319.1 - 0.037 12.7 1.1 0.057 12.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 OAJ11319.1 - 3.8 5.3 5.5 5.1 4.8 3.8 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L14 PF00238.14 OAJ11320.1 - 6.6e-42 142.1 0.7 7.8e-42 141.8 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RRM_1 PF00076.17 OAJ11330.1 - 6.7e-48 160.1 0.0 1.2e-22 79.2 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ11330.1 - 1.6e-37 127.2 0.0 1.6e-18 66.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ11330.1 - 2.4e-21 75.3 0.0 6.6e-10 38.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ11330.1 - 7.7e-06 25.7 8.2 0.013 15.3 0.0 3.8 4 0 0 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.1 OAJ11330.1 - 0.018 14.8 0.0 4.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Bud13 PF09736.4 OAJ11331.1 - 3.3e-08 33.9 6.7 3.3e-08 33.9 4.7 2.5 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DUF3275 PF11679.3 OAJ11331.1 - 0.05 13.2 3.7 0.074 12.6 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Herpes_US9 PF06072.6 OAJ11331.1 - 0.17 11.6 0.2 0.44 10.4 0.1 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF3350 PF11830.3 OAJ11331.1 - 2.1 8.4 5.9 32 4.6 2.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) RRM_1 PF00076.17 OAJ11332.1 - 1e-45 153.2 0.0 1.8e-22 78.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ11332.1 - 3e-38 129.6 0.0 1.6e-18 66.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ11332.1 - 8.8e-19 67.1 0.0 1.5e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ11332.1 - 3.3e-05 23.6 0.0 0.12 12.2 0.0 2.6 2 1 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 OAJ11332.1 - 0.0094 15.6 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 OAJ11332.1 - 0.052 13.1 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Calcipressin NTPase_P4 PF11602.3 OAJ11333.1 - 0.13 11.2 1.1 0.14 11.1 0.8 1.0 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 SNAP PF14938.1 OAJ11334.1 - 4e-93 311.6 11.8 4.5e-93 311.4 8.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 OAJ11334.1 - 1.3e-07 31.1 16.9 0.00023 20.7 1.5 3.8 1 1 3 4 4 4 4 TPR repeat TPR_12 PF13424.1 OAJ11334.1 - 6.5e-06 25.9 13.9 0.004 17.0 0.4 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ11334.1 - 0.00038 21.0 26.5 0.0048 17.5 1.5 4.6 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ11334.1 - 0.0073 16.6 17.8 17 6.1 0.2 6.6 5 2 1 6 6 6 0 Tetratricopeptide repeat Spatacsin_C PF14649.1 OAJ11334.1 - 0.0085 14.9 3.1 0.17 10.7 0.4 2.2 1 1 0 2 2 2 2 Spatacsin C-terminus TPR_9 PF13371.1 OAJ11334.1 - 0.011 15.5 5.2 1.4 8.8 0.1 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat PerC PF06069.6 OAJ11334.1 - 0.027 14.5 0.7 1.8 8.6 0.1 2.6 2 1 1 3 3 3 0 PerC transcriptional activator DUF4170 PF13773.1 OAJ11334.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4170) TPR_2 PF07719.12 OAJ11334.1 - 0.31 11.0 20.4 4.8 7.3 0.1 7.1 3 3 5 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ11334.1 - 0.34 10.7 13.3 3.3 7.7 0.1 5.5 4 2 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ11334.1 - 1.1 10.0 14.4 5.7 7.8 0.1 5.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ11334.1 - 2.4 7.9 18.4 3.5 7.4 0.1 6.7 6 2 2 8 8 8 0 Tetratricopeptide repeat DUF885 PF05960.6 OAJ11341.1 - 0.018 14.2 0.1 0.021 14.0 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Zip PF02535.17 OAJ11342.1 - 4.3e-36 124.5 14.3 4.3e-36 124.5 9.9 2.6 2 1 0 2 2 2 2 ZIP Zinc transporter SPOUT_MTase_2 PF14419.1 OAJ11351.1 - 0.098 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP LigB PF02900.13 OAJ11353.1 - 1.4e-30 106.1 0.6 7.4e-30 103.8 0.4 1.8 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Mrr_cat PF04471.7 OAJ11353.1 - 0.023 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease DUF2959 PF11172.3 OAJ11362.1 - 0.0047 16.7 0.3 0.0054 16.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) Acetyltransf_11 PF13720.1 OAJ11362.1 - 0.045 13.9 0.3 0.12 12.5 0.1 1.7 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 HisKA_3 PF07730.8 OAJ11362.1 - 0.067 13.5 1.6 0.85 10.0 0.5 2.0 1 1 1 2 2 2 0 Histidine kinase FUSC PF04632.7 OAJ11362.1 - 0.25 9.7 2.4 0.26 9.6 1.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Metal_resist PF13801.1 OAJ11363.1 - 0.036 14.0 1.7 0.057 13.4 1.2 1.2 1 0 0 1 1 1 0 Heavy-metal resistance Cutinase PF01083.17 OAJ11367.1 - 2.1e-28 99.2 0.0 3.1e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ11367.1 - 0.00082 18.9 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ11367.1 - 0.0049 16.7 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 OAJ11367.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Mitofilin PF09731.4 OAJ11379.1 - 3.5e-71 240.6 41.4 8.4e-44 150.2 24.2 2.8 2 1 0 2 2 2 2 Mitochondrial inner membrane protein DUF639 PF04842.7 OAJ11379.1 - 0.0068 14.6 0.2 0.014 13.5 0.2 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) CPSase_L_chain PF00289.17 OAJ11380.1 - 3.8e-05 23.7 0.0 4.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Abhydrolase_8 PF06259.7 OAJ11380.1 - 0.012 15.1 0.0 1.2 8.5 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase Peptidase_M17_N PF02789.12 OAJ11380.1 - 0.075 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Mtr2 PF10429.4 OAJ11387.1 - 0.058 13.1 0.0 0.69 9.6 0.0 2.3 1 1 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 NTF2 PF02136.15 OAJ11387.1 - 0.1 12.9 0.0 1.7 9.0 0.0 2.7 2 1 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain DUF1752 PF08550.5 OAJ11388.1 - 2.2e-10 39.9 3.9 4.6e-10 38.8 2.7 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) GTP_EFTU PF00009.22 OAJ11410.1 - 5.9e-59 198.6 0.5 9.2e-59 198.0 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 OAJ11410.1 - 1.1e-28 99.2 0.0 2.5e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 OAJ11410.1 - 3.1e-16 59.2 3.1 3.1e-16 59.2 2.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAJ11410.1 - 1.3e-05 25.1 0.1 2.9e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAJ11410.1 - 0.0047 17.4 0.1 0.0086 16.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 OAJ11410.1 - 0.075 12.5 0.4 9 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 OAJ11410.1 - 0.077 12.4 0.9 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zn_clus PF00172.13 OAJ11411.1 - 1.3e-08 34.5 10.4 2e-08 34.0 7.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim54 PF11711.3 OAJ11412.1 - 2.7e-49 167.7 0.0 4.5e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 adh_short PF00106.20 OAJ11413.1 - 0.00018 21.4 0.1 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 OAJ11413.1 - 0.0047 16.6 1.0 0.0091 15.7 0.7 1.6 1 1 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 OAJ11413.1 - 0.028 13.5 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AlaDh_PNT_N PF05222.10 OAJ11422.1 - 1.5e-27 96.2 0.0 2.4e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 OAJ11422.1 - 1e-07 31.6 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiC-associated PF13667.1 OAJ11422.1 - 0.075 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 ThiC-associated domain Cyclin_N PF00134.18 OAJ11423.1 - 0.00068 19.2 0.1 0.00068 19.2 0.1 2.9 4 0 0 4 4 4 1 Cyclin, N-terminal domain TMEM237 PF15383.1 OAJ11423.1 - 0.73 8.9 3.2 1.2 8.2 2.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 tRNA-synt_1e PF01406.14 OAJ11431.1 - 1.1 8.3 0.0 1.7 7.6 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Ku PF02735.11 OAJ11441.1 - 8.1e-26 90.6 0.0 4.7e-22 78.3 0.0 2.3 2 0 0 2 2 2 2 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 OAJ11441.1 - 2.9e-14 53.0 0.1 1e-13 51.2 0.0 1.8 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 OAJ11441.1 - 5.4e-08 32.1 0.2 1.4e-07 30.8 0.2 1.7 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 OAJ11441.1 - 9.2e-05 22.8 0.2 0.12 12.9 0.0 2.9 2 0 0 2 2 2 2 Ku70/Ku80 C-terminal arm Nop53 PF07767.6 OAJ11441.1 - 0.0014 17.6 1.6 0.0023 16.9 1.1 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) BNIP2 PF12496.3 OAJ11441.1 - 0.036 14.2 1.4 0.086 13.0 1.0 1.6 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Med4 PF10018.4 OAJ11442.1 - 4.6e-19 68.5 4.5 6.5e-19 68.0 3.1 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 zf-CpG_bind_C PF12269.3 OAJ11442.1 - 0.55 9.6 3.0 0.8 9.1 1.5 1.6 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain CBFD_NFYB_HMF PF00808.18 OAJ11443.1 - 4.8e-13 48.9 0.4 8.9e-13 48.1 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAJ11443.1 - 0.00024 21.1 0.5 0.0004 20.4 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Prothymosin PF03247.9 OAJ11443.1 - 0.058 13.5 10.2 0.15 12.2 7.1 1.7 1 0 0 1 1 1 0 Prothymosin/parathymosin family Thioredoxin PF00085.15 OAJ11454.1 - 1.3e-61 204.6 0.3 1e-26 92.6 0.0 4.4 4 1 0 4 4 4 4 Thioredoxin Thioredoxin_6 PF13848.1 OAJ11454.1 - 1.1e-44 152.4 0.1 9e-38 129.9 0.2 3.4 2 2 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAJ11454.1 - 1.6e-15 56.9 0.3 0.0038 17.3 0.0 4.5 4 0 0 4 4 4 4 Thioredoxin-like Calsequestrin PF01216.12 OAJ11454.1 - 3.2e-14 52.5 0.9 5.1e-14 51.8 0.1 1.7 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_2 PF13098.1 OAJ11454.1 - 4e-13 49.5 4.9 0.00018 21.7 0.1 5.1 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 OAJ11454.1 - 6.2e-10 38.9 0.1 0.00051 20.0 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 OAJ11454.1 - 1.4e-06 28.0 1.7 0.019 14.6 0.0 3.4 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.5 OAJ11454.1 - 3.9e-05 23.2 2.4 0.25 10.8 0.0 3.5 3 0 0 3 3 3 2 Redoxin Thioredoxin_4 PF13462.1 OAJ11454.1 - 0.00019 21.4 3.3 0.14 12.1 0.0 3.5 3 1 0 3 3 3 2 Thioredoxin ERp29_N PF07912.8 OAJ11454.1 - 0.011 15.6 0.0 0.26 11.2 0.0 2.6 2 0 0 2 2 2 0 ERp29, N-terminal domain Thioredoxin_5 PF13743.1 OAJ11454.1 - 0.11 12.0 0.7 20 4.6 0.0 3.4 3 1 0 3 3 3 0 Thioredoxin Glutaredoxin PF00462.19 OAJ11454.1 - 0.12 12.3 0.4 25 4.9 0.0 3.7 4 1 0 4 4 4 0 Glutaredoxin PAT1 PF09770.4 OAJ11455.1 - 5.7 5.0 41.8 9.8 4.2 29.0 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-DHHC PF01529.15 OAJ11464.1 - 1.8e-42 144.6 1.3 5.3e-42 143.1 0.0 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase COX17 PF05051.8 OAJ11465.1 - 7.1e-18 64.3 5.7 1.2e-17 63.6 4.0 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Abhydrolase_6 PF12697.2 OAJ11466.1 - 0.0091 15.8 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family zf-CCHC PF00098.18 OAJ11487.1 - 0.21 11.5 3.8 0.78 9.7 2.6 2.1 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.21 OAJ11488.1 - 3.1e-14 53.1 0.0 6.2e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain AAA PF00004.24 OAJ11508.1 - 6.8e-58 194.5 0.0 3.7e-45 153.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ11508.1 - 8.5e-08 32.3 5.7 0.011 15.7 0.1 4.3 3 1 1 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 OAJ11508.1 - 1.9e-07 31.9 0.0 0.0084 16.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 OAJ11508.1 - 5.6e-06 26.2 0.0 0.073 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 OAJ11508.1 - 2.1e-05 24.2 0.1 0.018 14.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 OAJ11508.1 - 6e-05 22.5 0.3 0.045 13.1 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ11508.1 - 6.1e-05 22.7 0.0 0.0069 16.1 0.0 3.2 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 OAJ11508.1 - 7.1e-05 22.9 0.1 0.0061 16.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 OAJ11508.1 - 0.00029 21.1 0.0 0.16 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAJ11508.1 - 0.00041 20.2 0.0 0.21 11.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 OAJ11508.1 - 0.00068 18.7 0.0 0.0057 15.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 OAJ11508.1 - 0.0013 18.6 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 OAJ11508.1 - 0.0013 18.7 0.0 2.9 7.9 0.0 2.7 3 0 0 3 3 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 OAJ11508.1 - 0.0016 17.8 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 OAJ11508.1 - 0.0017 17.8 0.0 1.7 8.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 OAJ11508.1 - 0.0022 16.9 0.0 1.7 7.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) KaiC PF06745.8 OAJ11508.1 - 0.0028 16.7 0.3 0.006 15.7 0.0 1.5 2 0 0 2 2 2 1 KaiC TIP49 PF06068.8 OAJ11508.1 - 0.0033 16.2 0.0 0.032 12.9 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_2 PF07724.9 OAJ11508.1 - 0.0063 16.4 0.0 0.016 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.7 OAJ11508.1 - 0.0073 15.9 0.9 3.2 7.4 0.0 3.3 4 0 0 4 4 4 1 NACHT domain Parvo_NS1 PF01057.12 OAJ11508.1 - 0.0089 14.9 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.16 OAJ11508.1 - 0.016 14.3 1.1 0.048 12.8 0.1 2.2 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 OAJ11508.1 - 0.021 14.9 0.0 0.097 12.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_3 PF07726.6 OAJ11508.1 - 0.042 13.4 0.0 0.55 9.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 OAJ11508.1 - 0.043 13.0 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 OAJ11508.1 - 0.054 13.0 0.2 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 OAJ11508.1 - 0.08 12.5 0.1 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 OAJ11508.1 - 0.1 12.4 0.0 8.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase T2SE PF00437.15 OAJ11508.1 - 0.16 10.8 0.0 2.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 OAJ11508.1 - 0.17 10.9 0.0 0.52 9.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.17 OAJ11508.1 - 0.23 10.2 0.0 1.5 7.6 0.0 2.1 3 0 0 3 3 3 0 NB-ARC domain NTPase_1 PF03266.10 OAJ11508.1 - 0.28 10.8 0.0 4.8 6.8 0.0 2.2 2 0 0 2 2 2 0 NTPase CBM_21 PF03370.8 OAJ11517.1 - 3e-30 104.4 0.1 5.2e-30 103.7 0.1 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit DUF3712 PF12505.3 OAJ11536.1 - 9.6e-24 83.8 0.0 4.8e-12 46.0 0.0 4.7 4 0 0 4 4 4 4 Protein of unknown function (DUF3712) TMEM171 PF15471.1 OAJ11537.1 - 0.4 9.4 2.1 0.59 8.8 1.5 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 RVT_1 PF00078.22 OAJ11549.1 - 1.6e-23 83.2 0.0 3.1e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4210 PF13915.1 OAJ11562.1 - 3.5e-17 62.4 1.7 3e-16 59.4 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 OAJ11562.1 - 1.2e-11 44.2 0.0 2.7e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis adh_short PF00106.20 OAJ11562.1 - 0.0037 17.1 1.1 0.011 15.6 0.8 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Aldose_epim PF01263.15 OAJ11563.1 - 5.8e-30 104.4 0.0 7.2e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Alg6_Alg8 PF03155.10 OAJ11564.1 - 0.12 11.2 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 ALG6, ALG8 glycosyltransferase family GrpE PF01025.14 OAJ11578.1 - 0.082 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 GrpE Erf4 PF10256.4 OAJ11589.1 - 1.2e-30 105.7 0.0 1.5e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Adap_comp_sub PF00928.16 OAJ11590.1 - 5.6e-67 225.6 0.1 8.7e-67 224.9 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 OAJ11590.1 - 7.8e-06 25.6 0.8 1.4e-05 24.8 0.3 1.6 1 1 1 2 2 2 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 OAJ11590.1 - 0.022 14.6 0.2 0.046 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) RNA_pol_Rpb5_C PF01191.14 OAJ11591.1 - 5e-34 115.7 0.1 9.9e-34 114.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 OAJ11591.1 - 1.9e-30 105.1 0.4 5.8e-30 103.5 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 OAJ11591.1 - 8.6e-05 22.3 0.1 0.00025 20.8 0.0 1.8 2 0 0 2 2 2 1 Restriction endonuclease BLVR PF06375.6 OAJ11591.1 - 0.076 12.8 3.7 0.31 10.8 2.3 1.9 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Ebola_NP PF05505.7 OAJ11591.1 - 0.27 9.2 0.0 0.27 9.2 0.0 2.0 2 0 0 2 2 2 0 Ebola nucleoprotein Drf_DAD PF06345.6 OAJ11603.1 - 0.12 12.2 0.2 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 DRF Autoregulatory Domain RVT_2 PF07727.9 OAJ11604.1 - 1.3e-83 279.7 0.0 2e-83 279.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ11604.1 - 4.7e-24 84.7 0.0 4.9e-23 81.5 0.0 2.6 2 1 1 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ11604.1 - 3.6e-07 29.7 0.0 3.6e-06 26.5 0.0 2.5 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ11604.1 - 7e-05 22.2 0.0 0.00017 21.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain UBN2 PF14223.1 OAJ11604.1 - 0.00031 20.4 0.0 0.00067 19.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Transcript_VP30 PF11507.3 OAJ11604.1 - 0.024 14.4 0.1 0.05 13.4 0.1 1.4 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 RVT_1 PF00078.22 OAJ11604.1 - 0.078 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PPR_2 PF13041.1 OAJ11615.1 - 3.3e-14 52.5 0.0 0.0041 17.0 0.0 6.5 5 1 1 6 6 6 4 PPR repeat family PPR_3 PF13812.1 OAJ11615.1 - 1.7e-13 49.6 17.9 0.0063 16.7 0.1 7.9 8 0 0 8 8 8 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 OAJ11615.1 - 4.7e-07 29.1 4.7 0.068 12.6 0.0 5.5 6 1 0 6 6 6 2 PPR repeat PPR PF01535.15 OAJ11615.1 - 1.2e-05 24.9 8.9 0.063 13.2 0.0 6.2 6 1 0 6 6 6 2 PPR repeat Peptidase_C48 PF02902.14 OAJ11628.1 - 9e-11 41.7 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.4 OAJ11628.1 - 0.00042 20.4 0.3 0.013 15.6 0.1 2.8 2 1 0 2 2 2 1 MULE transposase domain SWIM PF04434.12 OAJ11628.1 - 0.027 13.9 0.6 0.07 12.6 0.4 1.6 1 0 0 1 1 1 0 SWIM zinc finger Prok-JAB PF14464.1 OAJ11629.1 - 0.042 13.4 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain BSP_II PF05432.6 OAJ11629.1 - 0.8 8.9 10.7 1.2 8.3 7.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Serine_rich PF08824.5 OAJ11640.1 - 0.073 12.7 0.3 0.17 11.6 0.2 1.6 1 1 0 1 1 1 0 Serine rich protein interaction domain KCl_Cotrans_1 PF03522.10 OAJ11640.1 - 0.89 9.1 3.5 4 7.0 2.4 2.2 1 1 0 1 1 1 0 K-Cl Co-transporter type 1 (KCC1) MARVEL PF01284.18 OAJ11641.1 - 1.5e-07 31.3 16.8 2.3e-07 30.7 11.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF3784 PF12650.2 OAJ11641.1 - 8.6 6.3 8.6 0.49 10.3 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF621 PF04789.10 OAJ11642.1 - 4.9 6.0 8.6 4.7 6.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF621) Apo-CII PF05355.6 OAJ11648.1 - 0.0049 16.7 0.0 0.017 14.9 0.0 1.9 2 0 0 2 2 2 1 Apolipoprotein C-II Zn_clus PF00172.13 OAJ11649.1 - 1.3 9.0 5.7 4.6 7.2 4.0 1.9 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CsoSCA PF08936.5 OAJ11650.1 - 0.11 10.8 0.0 0.11 10.7 0.0 1.0 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase RVT_2 PF07727.9 OAJ11661.1 - 2.6e-72 242.7 0.0 3.4e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 OAJ11661.1 - 0.035 13.8 0.1 0.38 10.5 0.0 2.5 2 0 0 2 2 2 0 Reverse transcriptase-like PQ-loop PF04193.9 OAJ11662.1 - 4.2e-14 51.8 0.2 9.7e-14 50.6 0.1 1.6 1 0 0 1 1 1 1 PQ loop repeat WWbp PF10349.4 OAJ11662.1 - 1.1 10.2 11.1 0.23 12.3 3.6 2.3 2 0 0 2 2 2 0 WW-domain ligand protein DUF3435 PF11917.3 OAJ11675.1 - 0.15 10.7 2.9 0.22 10.1 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Peptidase_S8 PF00082.17 OAJ11685.1 - 9.2e-56 189.0 3.9 1.3e-55 188.5 2.7 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 OAJ11685.1 - 1e-27 95.7 0.2 2e-27 94.7 0.1 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain F-box-like PF12937.2 OAJ11686.1 - 6.8e-12 44.9 0.1 6.8e-12 44.9 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ11686.1 - 1.4e-07 30.9 1.4 3.1e-07 29.8 0.1 2.1 2 0 0 2 2 2 1 F-box domain PQQ PF01011.16 OAJ11686.1 - 0.0071 15.8 0.1 0.23 11.0 0.0 2.5 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.1 OAJ11686.1 - 0.043 13.2 0.0 0.78 9.1 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain Mpp10 PF04006.7 OAJ11700.1 - 2e-07 29.8 14.6 2e-07 29.8 10.1 3.9 2 1 2 4 4 4 1 Mpp10 protein DENN PF02141.16 OAJ11701.1 - 2.2e-22 79.6 0.0 3.7e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain DUF3450 PF11932.3 OAJ11701.1 - 0.047 12.9 7.4 0.093 11.9 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GAS PF13851.1 OAJ11701.1 - 0.2 10.8 13.0 0.029 13.5 6.2 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.14 OAJ11701.1 - 0.27 8.9 17.7 0.023 12.4 8.9 1.5 2 0 0 2 2 2 0 Myosin tail OmpH PF03938.9 OAJ11701.1 - 0.62 9.9 10.6 0.14 12.0 4.4 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FlgM PF04316.8 OAJ11701.1 - 0.92 9.5 4.3 0.89 9.5 0.6 2.6 2 1 0 2 2 2 0 Anti-sigma-28 factor, FlgM Syntaxin PF00804.20 OAJ11701.1 - 0.97 9.6 10.9 6.9 6.8 0.5 2.7 2 0 0 2 2 2 0 Syntaxin AAA_13 PF13166.1 OAJ11701.1 - 1 7.7 6.4 0.38 9.1 1.9 1.8 2 0 0 2 2 2 0 AAA domain DUF342 PF03961.8 OAJ11701.1 - 1.1 7.6 2.5 2 6.7 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 OAJ11701.1 - 1.4 7.8 13.4 0.056 12.4 5.0 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 Atg14 PF10186.4 OAJ11701.1 - 2.1 7.1 13.3 0.79 8.6 3.8 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 OAJ11701.1 - 4.3 5.6 9.2 9.6 4.4 6.4 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Filament PF00038.16 OAJ11701.1 - 4.3 6.7 19.5 0.2 11.0 8.1 2.3 2 1 1 3 3 3 0 Intermediate filament protein Prominin PF05478.6 OAJ11701.1 - 6.5 4.1 2.7 11 3.3 1.8 1.2 1 0 0 1 1 1 0 Prominin TMF_TATA_bd PF12325.3 OAJ11701.1 - 8.8 6.0 16.1 1.2 8.9 5.8 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding IFT57 PF10498.4 OAJ11701.1 - 9 4.9 10.5 15 4.1 0.1 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF1423 PF07227.6 OAJ11701.1 - 9.1 4.8 9.4 14 4.2 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) DDE_3 PF13358.1 OAJ11713.1 - 4.1e-28 97.9 0.0 6.7e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAJ11713.1 - 3.9e-05 24.3 0.0 0.00012 22.7 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 OAJ11713.1 - 6.1e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix rve PF00665.21 OAJ11713.1 - 0.00032 20.8 0.0 0.00064 19.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_7 PF02796.10 OAJ11713.1 - 0.028 14.2 0.9 0.19 11.5 0.0 2.8 4 0 0 4 4 4 0 Helix-turn-helix domain of resolvase Transposase_mut PF00872.13 OAJ11713.1 - 0.15 10.6 0.1 12 4.3 0.0 2.1 2 0 0 2 2 2 0 Transposase, Mutator family Histone PF00125.19 OAJ11726.1 - 2.8e-10 40.1 0.1 6.6e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 BON PF04972.12 OAJ11726.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 BON domain DUF3450 PF11932.3 OAJ11728.1 - 0.018 14.3 0.3 0.061 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ADIP PF11559.3 OAJ11728.1 - 0.022 14.6 3.2 1.9 8.3 0.1 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 OAJ11728.1 - 0.61 9.6 3.4 0.65 9.5 0.1 2.3 2 1 0 2 2 2 0 Septum formation initiator Cep57_MT_bd PF06657.8 OAJ11728.1 - 0.66 9.9 5.5 0.37 10.7 0.3 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 rve PF00665.21 OAJ11743.1 - 5.5e-19 68.4 0.0 1.6e-18 66.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ11743.1 - 5.8e-15 55.2 0.0 1.5e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 OAJ11743.1 - 0.00042 20.1 8.0 0.00042 20.1 5.6 2.6 3 0 0 3 3 3 1 Zinc knuckle rve_3 PF13683.1 OAJ11743.1 - 0.028 13.9 0.0 0.074 12.5 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.22 OAJ11754.1 - 6.4e-25 87.7 0.1 1.4e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ11754.1 - 2.6e-20 72.7 0.0 2.1e-19 69.7 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain Retrotrans_gag PF03732.12 OAJ11754.1 - 5.6e-09 35.9 0.7 3.2e-08 33.5 0.0 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein RVP_2 PF08284.6 OAJ11754.1 - 0.00018 21.4 0.0 0.00053 19.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAJ11754.1 - 0.00023 21.6 0.0 0.00058 20.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ11754.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease BTAD PF03704.12 OAJ11765.1 - 0.032 14.5 1.2 0.18 12.1 0.2 2.1 2 0 0 2 2 2 0 Bacterial transcriptional activator domain RVT_1 PF00078.22 OAJ11766.1 - 5.7e-17 61.7 0.0 1.3e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ11766.1 - 1.4e-12 47.7 0.0 2.5e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ11766.1 - 0.031 14.7 0.1 0.11 13.0 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease Nramp PF01566.13 OAJ11766.1 - 0.67 8.6 0.1 1 8.0 0.1 1.2 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein Retrotrans_gag PF03732.12 OAJ11783.1 - 0.15 12.1 0.1 0.43 10.6 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.22 OAJ11784.1 - 3.9e-16 59.0 0.0 7.2e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ11784.1 - 0.00034 21.0 0.0 0.00074 19.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ11784.1 - 0.013 15.3 0.0 0.049 13.5 0.0 1.9 1 1 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ11784.1 - 0.018 14.8 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAJ11803.1 - 0.00017 21.9 0.0 0.00047 20.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease TAFH PF07531.9 OAJ11803.1 - 0.046 13.3 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 NHR1 homology to TAF RVP PF00077.15 OAJ11803.1 - 0.12 12.3 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Retroviral aspartyl protease RVT_1 PF00078.22 OAJ11804.1 - 7.7e-12 45.0 0.0 2e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ11804.1 - 5.3e-09 36.2 0.0 1.3e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain PH_10 PF15411.1 OAJ11819.1 - 1.3e-21 76.9 0.0 2.8e-21 75.8 0.0 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 OAJ11819.1 - 9.9e-05 22.0 0.0 0.014 15.0 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain PH PF00169.24 OAJ11819.1 - 0.072 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 PH domain Tub_2 PF04525.7 OAJ11820.1 - 2e-28 99.0 0.0 2.4e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 MFS_1 PF07690.11 OAJ11843.1 - 2e-17 62.9 45.4 2e-17 62.9 31.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAJ11843.1 - 2.8e-05 22.5 21.1 7.5e-05 21.1 14.6 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) K_channel_TID PF07941.6 OAJ11844.1 - 0.012 15.8 7.5 0.012 15.8 5.2 3.6 2 1 3 5 5 5 0 Potassium channel Kv1.4 tandem inactivation domain Nucleoplasmin PF03066.10 OAJ11844.1 - 0.59 9.6 6.1 0.23 10.9 2.2 1.8 2 0 0 2 2 2 0 Nucleoplasmin DUF1387 PF07139.6 OAJ11844.1 - 0.78 9.2 10.8 0.17 11.4 4.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) zf-DHHC PF01529.15 OAJ11845.1 - 1.3e-39 135.3 0.5 2.3e-39 134.5 0.3 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Arc_PepC_II PF06847.6 OAJ11845.1 - 2.7 8.4 5.6 0.4 11.1 0.8 1.9 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II rve PF00665.21 OAJ11857.1 - 1.3e-21 76.8 0.1 2.2e-21 76.1 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ11857.1 - 0.00048 19.5 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 OAJ11857.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 DDE domain RVT_1 PF00078.22 OAJ11858.1 - 7.2e-10 38.5 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CPSF_A PF03178.10 OAJ11869.1 - 1.4e-43 149.2 0.0 2.1e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 OAJ11869.1 - 1.2e-16 59.9 0.0 1.9e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CSTF2_hinge PF14327.1 OAJ11870.1 - 2.5e-27 94.7 6.5 6.3e-27 93.4 4.5 1.7 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 OAJ11870.1 - 1.7e-22 78.8 0.1 2.6e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ11870.1 - 9.5e-15 54.3 0.0 2.1e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 OAJ11870.1 - 1.9e-12 46.2 2.5 1.9e-12 46.2 1.7 2.8 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 OAJ11870.1 - 5.9e-07 29.2 0.0 1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) bZIP_1 PF00170.16 OAJ11888.1 - 0.00058 19.7 20.9 0.00067 19.5 9.6 2.7 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 OAJ11888.1 - 0.15 11.9 24.6 0.088 12.6 9.8 2.9 2 0 0 2 2 2 0 Basic region leucine zipper PWI PF01480.12 OAJ11895.1 - 7.9e-26 89.9 0.0 1.1e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 PWI domain DUF605 PF04652.11 OAJ11895.1 - 4.5 6.5 13.5 6.2 6.1 9.4 1.2 1 0 0 1 1 1 0 Vta1 like F-box-like PF12937.2 OAJ11896.1 - 0.0015 18.2 0.7 0.0048 16.5 0.1 2.3 2 0 0 2 2 2 1 F-box-like Rep_fac-A_C PF08646.5 OAJ11897.1 - 3e-55 185.9 2.2 6.2e-54 181.6 0.5 2.5 2 0 0 2 2 2 1 Replication factor-A C terminal domain Rep-A_N PF04057.7 OAJ11897.1 - 1.5e-24 85.6 0.0 3.5e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 OAJ11897.1 - 1.2e-13 50.7 0.4 1.6e-11 43.9 0.0 2.9 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 OAJ11897.1 - 0.00011 22.2 0.2 0.0057 16.7 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function DUF223 Phenol_Hydrox PF02332.13 OAJ11909.1 - 0.046 13.0 0.1 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase CIA30 PF08547.7 OAJ11948.1 - 0.022 14.6 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) CAF-1_p150 PF11600.3 OAJ11948.1 - 4.5 6.5 4.8 5.6 6.2 3.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF508 PF04370.7 OAJ11948.1 - 6.8 6.2 7.1 9.7 5.8 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Tim44 PF04280.10 OAJ11950.1 - 2.5e-14 53.4 2.4 5.1e-12 46.0 0.0 3.0 3 0 0 3 3 3 2 Tim44-like domain Sec10 PF07393.6 OAJ11959.1 - 1.7e-82 277.8 0.0 4e-78 263.3 0.0 2.1 2 0 0 2 2 2 2 Exocyst complex component Sec10 F-box-like PF12937.2 OAJ11959.1 - 0.0092 15.6 0.3 0.033 13.8 0.2 2.0 1 0 0 1 1 1 1 F-box-like tRNA-synt_1b PF00579.20 OAJ11960.1 - 2.9e-56 190.7 0.0 2.6e-55 187.6 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 OAJ11960.1 - 0.00075 18.8 0.1 0.0018 17.6 0.1 1.6 1 0 0 1 1 1 1 S4 domain Chitin_synth_1 PF01644.12 OAJ11960.1 - 0.19 11.5 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Chitin synthase Ctf8 PF09696.5 OAJ11972.1 - 8.5e-12 44.9 0.3 2.1e-11 43.6 0.2 1.6 1 1 0 1 1 1 1 Ctf8 zf-CCCH PF00642.19 OAJ11973.1 - 1.4e-18 66.0 14.9 6.3e-11 41.6 1.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 OAJ11973.1 - 10 6.3 11.0 0.79 9.8 0.3 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type SDA1 PF05285.7 OAJ11989.1 - 2.8e-71 240.4 57.4 5.2e-69 233.0 34.6 3.8 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 OAJ11989.1 - 3.5e-15 56.0 0.1 6.6e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 NUC130/3NT domain DEAD PF00270.24 OAJ11990.1 - 1.4e-32 112.5 0.0 5.5e-31 107.3 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 OAJ11990.1 - 3.9e-18 64.7 0.5 7e-18 63.9 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 OAJ11990.1 - 1.3e-17 63.3 0.0 3e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ11990.1 - 1.5e-05 24.8 0.0 6e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 OAJ11990.1 - 0.051 13.7 0.0 1.5 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF2315 PF10231.4 OAJ12001.1 - 1.2e-08 34.8 2.4 0.00012 21.9 0.8 2.6 2 1 0 2 2 2 2 Uncharacterised conserved protein (DUF2315) Aft1_OSA PF11785.3 OAJ12001.1 - 1.5 9.4 11.6 0.93 10.0 0.3 2.8 3 0 0 3 3 3 0 Aft1 osmotic stress response (OSM) domain MutS_V PF00488.16 OAJ12002.1 - 1.5e-95 319.0 0.0 2.3e-95 318.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAJ12002.1 - 9.6e-36 123.4 2.5 2.4e-35 122.1 0.2 2.3 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 OAJ12002.1 - 6.5e-19 67.8 0.4 2.4e-18 66.0 0.0 2.3 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 OAJ12002.1 - 2.3e-15 56.8 0.1 7.7e-15 55.1 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.15 OAJ12002.1 - 3.3e-15 56.0 0.0 1.2e-14 54.2 0.0 2.1 1 0 0 1 1 1 1 MutS domain I Syntaxin PF00804.20 OAJ12002.1 - 0.058 13.5 2.4 3.9 7.6 0.6 2.8 2 0 0 2 2 2 0 Syntaxin TBCA PF02970.11 OAJ12002.1 - 1.6 8.8 8.2 98 3.1 0.0 3.7 3 0 0 3 3 3 0 Tubulin binding cofactor A G_glu_transpept PF01019.16 OAJ12012.1 - 1.3e-138 462.6 0.1 2.4e-119 399.1 0.0 2.1 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase Peroxidase_2 PF01328.12 OAJ12013.1 - 1.6e-20 73.0 0.4 3.3e-20 71.9 0.3 1.5 1 1 0 1 1 1 1 Peroxidase, family 2 HAD_2 PF13419.1 OAJ12029.1 - 4.1e-14 53.1 0.0 2.9e-10 40.6 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAJ12029.1 - 2.4e-08 34.6 0.0 8.3e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 OAJ12029.1 - 0.042 13.7 0.0 8.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD PF12710.2 OAJ12029.1 - 0.044 13.9 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Stimulus_sens_1 PF13756.1 OAJ12029.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Stimulus-sensing domain FH2 PF02181.18 OAJ12030.1 - 7.5e-83 278.4 0.0 9.9e-83 278.0 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Chal_sti_synt_N PF00195.14 OAJ12046.1 - 0.039 13.2 0.1 0.041 13.1 0.0 1.0 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3416 PF11896.3 OAJ12047.1 - 0.0067 16.4 0.0 0.0069 16.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3416) Vip3A_N PF12495.3 OAJ12047.1 - 0.015 15.0 0.2 0.016 14.8 0.1 1.1 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal DUF2746 PF10874.3 OAJ12047.1 - 0.056 13.6 4.2 0.079 13.1 2.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2746) MutS_II PF05188.12 OAJ12048.1 - 1.4e-08 34.9 0.1 1.7e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 MutS domain II MutS_V PF00488.16 OAJ12049.1 - 4.2e-17 62.3 0.6 1.2e-11 44.4 0.2 2.3 1 1 1 2 2 2 2 MutS domain V MutS_V PF00488.16 OAJ12050.1 - 1.7e-07 30.9 0.2 3.9e-06 26.4 0.1 2.2 1 1 0 1 1 1 1 MutS domain V DUF2188 PF09954.4 OAJ12072.1 - 0.78 9.7 5.7 0.23 11.3 1.7 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) GATA PF00320.22 OAJ12072.1 - 1.1 8.6 5.7 2.2 7.6 4.0 1.5 1 0 0 1 1 1 0 GATA zinc finger HlyD PF00529.15 OAJ12072.1 - 7.9 5.6 15.8 9.8 5.3 11.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF155 PF02582.9 OAJ12087.1 - 2.7e-33 115.3 0.0 1.4e-16 60.9 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised ACR, YagE family COG1723 Ndc1_Nup PF09531.5 OAJ12087.1 - 0.26 9.6 10.7 0.45 8.8 7.4 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.8 OAJ12087.1 - 0.94 9.3 24.0 1.8 8.4 16.7 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex16 PF08610.5 OAJ12087.1 - 4.2 6.2 15.8 11 4.9 11.0 1.7 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Neur_chan_memb PF02932.11 OAJ12087.1 - 7 6.4 6.2 16 5.3 4.3 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.4 OAJ12087.1 - 7.3 4.6 43.1 11 4.0 29.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF106 PF01956.11 OAJ12087.1 - 8.4 5.8 8.4 19 4.7 5.7 1.6 2 0 0 2 2 2 0 Integral membrane protein DUF106 JmjC PF02373.17 OAJ12088.1 - 3.9e-38 130.2 0.5 7.3e-38 129.3 0.3 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 OAJ12088.1 - 1.8e-12 46.5 0.6 3.4e-12 45.6 0.4 1.5 1 0 0 1 1 1 1 jmjN domain DUF4463 PF14703.1 OAJ12088.1 - 0.0045 17.4 0.1 0.021 15.3 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) HMG_box PF00505.14 OAJ12104.1 - 3.3e-10 40.0 1.1 6.2e-10 39.2 0.8 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 OAJ12104.1 - 0.00014 21.2 0.2 0.00025 20.4 0.1 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 UPF0254 PF06787.6 OAJ12105.1 - 0.17 11.4 4.5 0.17 11.3 3.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) Coatomer_E PF04733.9 OAJ12113.1 - 6e-44 150.3 8.2 7.6e-44 150.0 5.7 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 OAJ12113.1 - 8.3e-05 22.8 24.4 0.00084 19.6 2.8 4.3 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ12113.1 - 0.00036 20.1 0.3 0.00036 20.1 0.2 3.6 3 1 2 5 5 5 1 TPR repeat TPR_2 PF07719.12 OAJ12113.1 - 1 9.4 0.1 1 9.4 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ12113.1 - 4.9 8.0 25.3 0.61 10.8 2.1 5.5 3 2 3 6 6 6 0 Tetratricopeptide repeat Mpv17_PMP22 PF04117.7 OAJ12114.1 - 7.1e-25 86.4 3.5 1.3e-24 85.5 2.4 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family tRNA-synt_1 PF00133.17 OAJ12115.1 - 5.7e-154 513.3 0.0 7.9e-154 512.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 OAJ12115.1 - 1.4e-28 99.5 0.0 2.6e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 OAJ12115.1 - 1.3e-20 73.4 0.3 5.5e-11 41.7 0.0 4.2 4 0 0 4 4 4 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 OAJ12115.1 - 0.0025 17.3 8.4 0.0056 16.2 5.8 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 OAJ12115.1 - 0.0046 16.2 0.0 0.0084 15.4 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 OAJ12115.1 - 0.021 13.9 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain JmjC PF02373.17 OAJ12143.1 - 1.3e-40 138.1 0.1 3e-40 136.9 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 OAJ12143.1 - 9.7e-12 44.2 0.1 2.2e-11 43.0 0.1 1.7 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 OAJ12143.1 - 1.2e-09 38.1 1.7 1.2e-09 38.1 1.2 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 OAJ12143.1 - 2.3e-09 37.2 4.0 1.4e-08 34.6 1.1 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain CENP-C_C PF11699.3 OAJ12155.1 - 3.3e-28 97.5 0.4 5.8e-28 96.7 0.2 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 OAJ12155.1 - 0.00024 20.5 0.0 0.0005 19.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Sirohm_synth_M PF14824.1 OAJ12155.1 - 0.028 13.3 0.6 3.2 6.7 0.2 2.5 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central AraC_binding PF02311.14 OAJ12155.1 - 0.2 11.3 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain 60KD_IMP PF02096.15 OAJ12156.1 - 4.6e-16 59.0 0.0 1.6e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 60Kd inner membrane protein GCR1_C PF12550.3 OAJ12174.1 - 3.2e-05 23.6 0.0 7.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_Tnp_1 PF01527.15 OAJ12174.1 - 0.031 14.2 0.3 0.2 11.6 0.0 2.6 2 0 0 2 2 2 0 Transposase HTH_23 PF13384.1 OAJ12174.1 - 0.047 13.3 2.2 0.2 11.3 0.0 3.3 3 0 0 3 3 3 0 Homeodomain-like domain HTH_28 PF13518.1 OAJ12174.1 - 0.1 12.5 3.1 0.31 11.0 0.0 3.3 4 0 0 4 4 4 0 Helix-turn-helix domain LTV PF04180.9 OAJ12194.1 - 3e-46 158.7 32.5 4.6e-46 158.1 13.4 2.7 2 1 0 2 2 2 2 Low temperature viability protein Peptidase_C8 PF03569.8 OAJ12194.1 - 0.093 12.0 0.7 0.21 10.8 0.5 1.6 1 0 0 1 1 1 0 Peptidase family C8 CwfJ_C_2 PF04676.9 OAJ12196.1 - 1.1e-17 64.3 0.0 1.4e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 FMO-like PF00743.14 OAJ12209.1 - 1.5e-33 115.7 0.0 4.9e-19 67.9 0.0 3.1 2 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 OAJ12209.1 - 2.3e-13 50.6 0.0 2.6e-12 47.2 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ12209.1 - 4.1e-06 25.9 0.3 0.0018 17.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAJ12209.1 - 5.4e-06 26.2 0.0 0.00024 20.9 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAJ12209.1 - 4.9e-05 23.3 0.0 0.13 12.1 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAJ12209.1 - 0.00047 20.1 0.1 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 OAJ12209.1 - 0.016 14.3 0.0 0.3 10.1 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Malic_M PF03949.10 OAJ12209.1 - 0.17 11.3 0.1 0.69 9.4 0.0 1.9 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Mating_C PF12737.2 OAJ12210.1 - 0.014 14.3 22.7 0.019 13.8 15.7 1.2 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 DUF572 PF04502.8 OAJ12210.1 - 0.069 12.3 15.2 0.094 11.9 10.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Macoilin PF09726.4 OAJ12210.1 - 0.83 7.8 8.3 1 7.5 5.8 1.3 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 OAJ12210.1 - 2.6 6.0 7.4 3 5.8 5.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FHA PF00498.21 OAJ12211.1 - 4.2e-14 52.4 0.0 7.5e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain ZapA PF05164.8 OAJ12212.1 - 0.0034 17.3 1.3 0.0064 16.4 0.9 1.4 1 0 0 1 1 1 1 Cell division protein ZapA RVT_1 PF00078.22 OAJ12224.1 - 1.2e-26 93.4 0.0 1.8e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ12224.1 - 4.4e-12 45.6 0.0 7.6e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ12224.1 - 0.0033 17.4 0.0 0.0058 16.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.19 OAJ12225.1 - 1.8e-13 50.9 0.0 2.8e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 RNase H NAD_binding_10 PF13460.1 OAJ12239.1 - 4.9e-11 42.9 0.0 6.6e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 OAJ12239.1 - 2.1e-09 37.5 4.4 9.1e-08 32.1 0.7 3.3 2 2 1 3 3 3 1 short chain dehydrogenase Epimerase PF01370.16 OAJ12239.1 - 1.4e-07 31.2 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 OAJ12239.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Ycf1 PF05758.7 OAJ12240.1 - 1.1 6.8 7.9 0.13 9.9 1.2 2.0 2 0 0 2 2 2 0 Ycf1 Hira PF07569.6 OAJ12240.1 - 1.3 8.2 8.3 2.3 7.3 5.8 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split DUF1510 PF07423.6 OAJ12240.1 - 1.7 7.9 21.5 0.43 9.8 4.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) FliP PF00813.15 OAJ12240.1 - 2.3 7.8 7.4 43 3.7 0.0 2.3 2 0 0 2 2 2 0 FliP family RRM_1 PF00076.17 OAJ12254.1 - 7.4e-10 38.3 0.0 1.7e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ12254.1 - 1.6e-09 37.4 0.0 2.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ12254.1 - 4.2e-09 36.2 0.0 7.2e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PGI PF00342.14 OAJ12255.1 - 7e-209 694.2 0.0 8.7e-209 693.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase SNF5 PF04855.7 OAJ12256.1 - 3.9e-51 173.8 2.3 4.3e-50 170.4 1.6 2.0 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 MBF1 PF08523.5 OAJ12257.1 - 7.1e-13 48.3 0.5 1.6e-12 47.2 0.3 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 OAJ12257.1 - 1.7e-11 43.7 0.3 3.1e-11 42.9 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 OAJ12257.1 - 5.4e-06 26.3 0.1 7.6e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 OAJ12257.1 - 0.00033 20.8 0.0 0.00053 20.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HpcH_HpaI PF03328.9 OAJ12257.1 - 0.027 13.3 0.0 0.029 13.2 0.0 1.2 1 1 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Cation_efflux PF01545.16 OAJ12289.1 - 3.7e-37 127.9 8.2 4.9e-37 127.5 5.7 1.2 1 0 0 1 1 1 1 Cation efflux family DUF1772 PF08592.6 OAJ12291.1 - 5.7e-13 48.7 1.3 9.5e-13 48.0 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Muskelin_N PF06588.6 OAJ12311.1 - 4.9e-23 81.8 0.0 8.2e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Muskelin N-terminus SOG2 PF10428.4 OAJ12311.1 - 2.5 6.6 13.5 3.7 6.0 9.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.4 OAJ12311.1 - 2.5 6.2 4.9 3.1 5.9 3.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Hamartin PF04388.7 OAJ12311.1 - 4.4 5.8 9.6 5.6 5.5 6.7 1.1 1 0 0 1 1 1 0 Hamartin protein RAP1 PF07218.6 OAJ12311.1 - 5.5 4.9 8.7 8.5 4.3 6.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MutS_III PF05192.13 OAJ12312.1 - 0.17 11.6 1.7 0.5 10.1 1.3 1.7 1 1 0 1 1 1 0 MutS domain III RVT_2 PF07727.9 OAJ12328.1 - 2.2e-81 272.4 0.0 2.8e-81 272.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAJ12328.1 - 0.0074 15.6 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2360 PF10152.4 OAJ12328.1 - 1.7 8.9 6.1 3.2 8.0 4.2 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Peptidase_M24 PF00557.19 OAJ12329.1 - 1.4e-41 142.3 0.1 1.9e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 CDC45 PF02724.9 OAJ12329.1 - 0.046 11.7 4.2 0.064 11.2 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BAF1_ABF1 PF04684.8 OAJ12329.1 - 1.6 7.5 8.0 2.3 6.9 5.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Nop14 PF04147.7 OAJ12329.1 - 3.9 5.2 8.3 6.2 4.5 5.8 1.2 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 OAJ12329.1 - 4.5 6.1 11.1 0.37 9.7 4.5 1.4 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Cnd2 PF05786.9 OAJ12329.1 - 5.1 5.4 8.9 7.2 4.9 6.2 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 UBN2 PF14223.1 OAJ12330.1 - 4.3e-10 39.4 0.6 7.9e-10 38.5 0.4 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ12330.1 - 8.3e-05 22.3 2.7 8.3e-05 22.3 1.9 1.6 2 0 0 2 2 2 1 Zinc knuckle UBN2_2 PF14227.1 OAJ12330.1 - 0.0029 17.1 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF413 PF04219.7 OAJ12330.1 - 0.31 10.7 1.8 0.61 9.8 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF YlbD_coat PF14071.1 OAJ12355.1 - 0.023 14.7 0.3 0.039 14.0 0.2 1.4 1 0 0 1 1 1 0 Putative coat protein Macoilin PF09726.4 OAJ12355.1 - 0.39 8.9 6.9 0.5 8.5 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S64 PF08192.6 OAJ12355.1 - 0.5 8.6 3.8 0.6 8.3 2.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 TATR PF03430.8 OAJ12355.1 - 1.8 7.0 5.3 2.7 6.5 3.7 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator SRA1 PF07304.6 OAJ12355.1 - 4.1 7.0 6.7 1.1 8.9 1.4 2.1 1 1 0 2 2 2 0 Steroid receptor RNA activator (SRA1) Asp_protease_2 PF13650.1 OAJ12356.1 - 7.4e-06 26.3 0.0 1.9e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ12356.1 - 9.1e-06 25.5 0.0 2.1e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 OAJ12356.1 - 3.3e-05 23.4 0.0 6.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 OAJ12356.1 - 4.9e-05 22.7 0.0 9.3e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rad60-SLD PF11976.3 OAJ12356.1 - 0.0028 17.2 0.5 0.019 14.6 0.1 2.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like gag-asp_proteas PF13975.1 OAJ12356.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 OAJ12356.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease SBF PF01758.11 OAJ12369.1 - 2.2e-39 134.8 15.6 2.2e-39 134.8 10.8 2.1 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF3169 PF11368.3 OAJ12369.1 - 0.027 13.6 0.4 0.027 13.6 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) MFS_1 PF07690.11 OAJ12370.1 - 1e-41 142.8 51.1 1e-41 142.8 35.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ12370.1 - 2.2e-10 39.6 9.7 2.2e-10 39.6 6.7 3.2 2 1 0 3 3 3 2 Sugar (and other) transporter Ank_2 PF12796.2 OAJ12371.1 - 0.16 12.3 0.0 0.7 10.2 0.0 2.1 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) SR-25 PF10500.4 OAJ12371.1 - 7.8 5.8 9.2 6.9 6.0 1.1 2.9 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Helitron_like_N PF14214.1 OAJ12390.1 - 9.4e-11 41.7 0.2 2.8e-10 40.2 0.2 1.9 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Toxin_29 PF08116.6 OAJ12390.1 - 0.4 10.5 2.7 0.82 9.5 1.9 1.4 1 0 0 1 1 1 0 PhTx neurotoxin family UPF0203 PF05254.7 OAJ12425.1 - 1.9e-12 46.8 0.0 2.3e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0203) Serglycin PF04360.7 OAJ12425.1 - 0.23 11.1 5.9 0.39 10.4 0.0 2.2 2 0 0 2 2 2 0 Serglycin Pol_alpha_B_N PF08418.5 OAJ12425.1 - 6.7 6.1 7.5 8.7 5.7 5.2 1.3 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF1517 PF07466.6 OAJ12425.1 - 8.9 5.1 8.5 17 4.3 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Rubredoxin PF00301.15 OAJ12426.1 - 0.085 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Rubredoxin Raftlin PF15250.1 OAJ12426.1 - 4.4 5.7 10.0 3.4 6.1 0.1 2.1 2 0 0 2 2 2 0 Raftlin AdoMet_MTase PF07757.8 OAJ12427.1 - 1.1e-30 105.9 0.0 1.4e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 OAJ12427.1 - 0.022 14.4 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain zf-Tim10_DDP PF02953.10 OAJ12428.1 - 9.7e-18 63.2 0.8 1.2e-17 62.8 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PCI PF01399.22 OAJ12429.1 - 5.6e-15 55.5 0.0 3e-14 53.1 0.0 2.2 2 1 0 2 2 2 1 PCI domain SpoU_methylas_C PF12105.3 OAJ12441.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal Collagen PF01391.13 OAJ12442.1 - 1e-17 63.4 71.8 5.8e-10 38.5 22.7 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF4401 PF14351.1 OAJ12443.1 - 2.6 6.9 12.2 0.034 13.1 2.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) Methyltransf_23 PF13489.1 OAJ12458.1 - 0.032 13.9 0.0 0.045 13.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ12458.1 - 0.089 13.3 0.6 1.7 9.2 0.2 2.7 2 1 0 2 2 2 0 Methyltransferase domain TehB PF03848.9 OAJ12458.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_25 PF13649.1 OAJ12458.1 - 0.12 12.6 0.1 0.33 11.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Thymidylat_synt PF00303.14 OAJ12459.1 - 2.3e-105 351.4 0.0 3.5e-105 350.8 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.17 OAJ12459.1 - 3.1e-29 102.0 0.1 9.3e-29 100.5 0.1 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Cid2 PF09774.4 OAJ12460.1 - 0.05 13.7 0.4 0.064 13.3 0.3 1.3 1 1 0 1 1 1 0 Caffeine-induced death protein 2 WD40 PF00400.27 OAJ12473.1 - 1.9e-63 208.2 26.5 5.9e-12 44.9 0.4 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 OAJ12473.1 - 2.2e-07 30.7 0.0 0.0014 18.3 0.0 3.6 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 OAJ12473.1 - 3.5e-07 28.7 8.6 0.026 12.6 0.2 5.6 2 1 3 5 5 5 4 Nucleoporin Nup120/160 DUF3312 PF11768.3 OAJ12473.1 - 0.041 12.0 0.0 0.083 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Orbi_VP6 PF01516.11 OAJ12473.1 - 0.18 10.8 3.5 0.36 9.8 2.4 1.4 1 0 0 1 1 1 0 Orbivirus helicase VP6 SR-25 PF10500.4 OAJ12473.1 - 0.25 10.7 5.6 0.57 9.6 3.9 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ras PF00071.17 OAJ12474.1 - 2.3e-33 114.8 0.5 4.7e-16 58.5 0.0 2.0 1 1 1 2 2 2 2 Ras family Miro PF08477.8 OAJ12474.1 - 1.1e-08 35.6 0.5 7.2e-07 29.7 0.1 2.1 1 1 1 2 2 2 1 Miro-like protein AAA_22 PF13401.1 OAJ12474.1 - 0.0026 17.8 0.0 0.0036 17.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain Arf PF00025.16 OAJ12474.1 - 0.01 15.0 0.0 0.68 9.1 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family MobB PF03205.9 OAJ12474.1 - 0.016 14.9 0.1 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 OAJ12474.1 - 0.018 14.9 0.2 0.026 14.4 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ12474.1 - 0.019 14.2 0.0 4.3 6.5 0.0 2.2 1 1 0 2 2 2 0 Ferrous iron transport protein B DUF258 PF03193.11 OAJ12474.1 - 0.071 12.3 0.2 0.11 11.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 OAJ12474.1 - 0.12 11.6 1.0 0.42 9.8 0.0 2.0 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit ArsR PF09824.4 OAJ12476.1 - 0.011 15.0 0.2 0.017 14.4 0.2 1.3 1 0 0 1 1 1 0 ArsR transcriptional regulator DUF3373 PF11853.3 OAJ12476.1 - 0.06 11.8 2.0 0.066 11.7 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Calici_MSP PF05752.6 OAJ12476.1 - 0.2 11.2 2.6 0.26 10.8 1.8 1.2 1 0 0 1 1 1 0 Calicivirus minor structural protein FAM117 PF15388.1 OAJ12476.1 - 0.73 9.0 7.2 0.86 8.7 5.0 1.1 1 0 0 1 1 1 0 Protein Family FAM117 PA26 PF04636.8 OAJ12476.1 - 0.92 8.1 6.0 1 7.9 4.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SPX PF03105.14 OAJ12476.1 - 1.5 8.5 15.7 2.6 7.7 10.9 1.3 1 1 0 1 1 1 0 SPX domain Herpes_UL25 PF01499.11 OAJ12476.1 - 1.9 6.7 14.6 2.4 6.3 10.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF3450 PF11932.3 OAJ12476.1 - 3.1 6.9 15.8 1.7 7.8 8.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) UPF0449 PF15136.1 OAJ12476.1 - 3.4 7.9 10.6 0.49 10.6 4.1 2.0 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 REV PF00424.13 OAJ12476.1 - 4.1 7.3 7.7 1.1 9.1 3.0 1.9 2 1 0 2 2 2 0 REV protein (anti-repression trans-activator protein) GAS PF13851.1 OAJ12476.1 - 4.9 6.2 19.9 14 4.7 13.8 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding zf-BED PF02892.10 OAJ12489.1 - 0.0055 16.4 1.7 0.0095 15.6 1.1 1.4 1 0 0 1 1 1 1 BED zinc finger Cep57_CLD_2 PF14197.1 OAJ12492.1 - 0.91 9.5 3.0 13 5.8 0.1 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 UBN2 PF14223.1 OAJ12502.1 - 0.0021 17.8 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ12502.1 - 0.031 14.2 8.3 0.064 13.2 5.8 1.6 1 0 0 1 1 1 0 Zinc knuckle MULE PF10551.4 OAJ12504.1 - 5e-18 65.0 0.0 1.4e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.10 OAJ12504.1 - 2.5e-12 46.1 0.1 6.2e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.13 OAJ12504.1 - 6.9e-07 28.1 0.1 1.3e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 Transposase, Mutator family Ion_trans_N PF08412.5 OAJ12504.1 - 0.049 12.9 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Ion transport protein N-terminal WH1 PF00568.18 OAJ12504.1 - 0.084 12.5 0.2 0.23 11.1 0.1 1.7 2 0 0 2 2 2 0 WH1 domain WW PF00397.21 OAJ12516.1 - 0.031 14.1 0.2 0.071 12.9 0.1 1.6 1 0 0 1 1 1 0 WW domain Glyco_transf_22 PF03901.12 OAJ12518.1 - 1.7e-70 238.1 14.7 1.3e-68 231.9 10.0 2.0 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family Prenyltrans PF00432.16 OAJ12532.1 - 2.3e-21 75.0 11.8 1.7e-07 30.6 0.0 3.9 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 OAJ12532.1 - 2.2e-12 47.4 0.0 2.1e-11 44.2 0.0 2.1 1 1 1 2 2 2 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 OAJ12532.1 - 0.00014 21.8 0.0 0.00074 19.4 0.0 2.1 1 1 1 2 2 2 1 Prenyltransferase-like Helicase_C_4 PF13871.1 OAJ12532.1 - 0.064 12.6 0.0 0.09 12.1 0.0 1.1 1 0 0 1 1 1 0 Helicase_C-like PIP5K PF01504.13 OAJ12533.1 - 6.6e-82 274.3 0.0 1.6e-81 273.1 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DDHD PF02862.12 OAJ12533.1 - 5.6 6.6 9.7 0.9 9.2 1.3 2.6 3 1 0 3 3 3 0 DDHD domain Arm PF00514.18 OAJ12534.1 - 2.1e-70 230.3 32.4 6.3e-13 48.0 0.1 12.2 11 1 2 13 13 13 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 OAJ12534.1 - 7.1e-25 87.1 11.7 2.1e-06 27.9 0.1 7.4 2 1 5 7 7 7 7 HEAT repeats HEAT PF02985.17 OAJ12534.1 - 5.6e-19 66.4 12.4 0.074 13.1 0.0 9.1 8 0 0 8 8 8 6 HEAT repeat HEAT_EZ PF13513.1 OAJ12534.1 - 6.3e-16 58.3 9.2 0.012 16.0 0.0 8.3 7 2 3 10 10 10 5 HEAT-like repeat Adaptin_N PF01602.15 OAJ12534.1 - 1.1e-10 40.4 11.9 1.7e-08 33.2 0.6 2.4 2 1 1 3 3 3 2 Adaptin N terminal region KAP PF05804.7 OAJ12534.1 - 2.5e-10 38.9 1.8 3.9e-10 38.3 1.2 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 OAJ12534.1 - 2.3e-09 36.7 11.5 2.6e-05 23.4 3.6 3.8 1 1 0 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.9 OAJ12534.1 - 4.6e-08 32.5 9.4 0.0003 19.9 0.8 4.5 1 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.3 OAJ12534.1 - 0.00031 20.6 5.3 2.8 7.9 0.1 4.8 2 1 3 5 5 5 2 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 OAJ12534.1 - 0.018 15.3 0.1 2.4 8.5 0.0 3.2 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 OAJ12534.1 - 0.021 15.2 9.8 94 3.9 0.0 7.4 9 0 0 9 9 8 0 PBS lyase HEAT-like repeat DUF3361 PF11841.3 OAJ12534.1 - 0.024 14.3 8.1 0.58 9.8 0.1 3.9 2 2 1 3 3 3 0 Domain of unknown function (DUF3361) Tom37 PF10568.4 OAJ12534.1 - 0.1 12.8 3.1 3.4 8.0 0.0 4.0 5 0 0 5 5 4 0 Outer mitochondrial membrane transport complex protein YqfD PF06898.6 OAJ12534.1 - 0.12 11.0 0.0 0.23 10.1 0.0 1.4 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD IBN_N PF03810.14 OAJ12534.1 - 0.14 12.0 3.6 6 6.8 0.1 4.1 4 0 0 4 4 4 0 Importin-beta N-terminal domain CDP-OH_P_transf PF01066.16 OAJ12556.1 - 2.4e-11 43.8 6.7 2.4e-11 43.8 4.7 3.5 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.20 OAJ12557.1 - 2.9e-50 170.8 0.0 4.8e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ12557.1 - 1.7e-43 148.6 0.0 2.3e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 OAJ12557.1 - 0.001 18.7 6.4 0.002 17.7 4.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.18 OAJ12557.1 - 0.0024 17.6 0.4 0.0049 16.6 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ12557.1 - 0.056 12.4 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-HC5HC2H_2 PF13832.1 OAJ12557.1 - 0.24 11.4 3.6 0.48 10.4 2.5 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain FAM60A PF15396.1 OAJ12557.1 - 0.26 11.0 8.6 0.71 9.5 6.0 1.7 1 0 0 1 1 1 0 Protein Family FAM60A Mcm10 PF09332.6 OAJ12557.1 - 0.27 10.5 9.3 0.66 9.2 6.4 1.6 1 0 0 1 1 1 0 Mcm10 replication factor Pox_ser-thr_kin PF05445.6 OAJ12557.1 - 0.42 9.3 0.0 0.61 8.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TFIIF_alpha PF05793.7 OAJ12557.1 - 0.6 8.4 20.1 0.018 13.4 8.7 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SOG2 PF10428.4 OAJ12557.1 - 2.5 6.6 11.4 5.1 5.6 7.9 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein MIP-T3 PF10243.4 OAJ12557.1 - 4.6 5.5 22.8 0.3 9.5 11.5 1.9 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Paf1 PF03985.8 OAJ12557.1 - 4.6 5.8 12.6 9.8 4.7 8.8 1.5 1 0 0 1 1 1 0 Paf1 DUF4614 PF15391.1 OAJ12557.1 - 8.2 6.1 13.3 19 4.9 9.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Phage_integrase PF00589.17 OAJ12570.1 - 2.9e-06 27.0 0.0 1.1e-05 25.1 0.0 1.6 1 1 1 2 2 2 1 Phage integrase family Asp_protease_2 PF13650.1 OAJ12580.1 - 5.5e-05 23.5 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ12580.1 - 0.0035 17.2 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ12580.1 - 0.023 14.5 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 OAJ12581.1 - 0.002 18.1 1.5 0.0031 17.5 0.4 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein Ras PF00071.17 OAJ12611.1 - 3.7e-33 114.2 0.0 4.2e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ12611.1 - 2.3e-13 50.6 0.0 2.6e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ12611.1 - 2e-08 33.6 0.0 2.2e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 OAJ12611.1 - 0.00039 20.3 0.0 0.00045 20.1 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 OAJ12611.1 - 0.0004 19.5 0.0 0.00047 19.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 OAJ12611.1 - 0.026 13.7 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 G-alpha PF00503.15 OAJ12611.1 - 0.041 12.5 0.1 4.2 5.9 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.1 OAJ12611.1 - 0.052 13.5 0.0 0.062 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 OAJ12611.1 - 0.092 12.8 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.17 OAJ12612.1 - 2.5e-17 62.2 0.0 2.3e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ12612.1 - 2.6e-10 39.9 0.0 2e-07 30.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ12612.1 - 5.4e-07 29.5 0.0 5.2e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Aldo_ket_red PF00248.16 OAJ12613.1 - 1.7e-69 233.8 0.0 1.9e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GCR1_C PF12550.3 OAJ12639.1 - 8.8e-15 54.3 0.0 1.8e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Sporozoite_P67 PF05642.6 OAJ12639.1 - 0.1 10.4 3.5 0.17 9.6 2.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ATP_synt_H PF05493.8 OAJ12640.1 - 9.8e-22 76.8 3.3 1.2e-21 76.5 2.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit H Claudin_2 PF13903.1 OAJ12640.1 - 0.072 12.7 6.2 0.079 12.6 4.3 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2456 PF10445.4 OAJ12640.1 - 0.3 11.0 3.1 7.8 6.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) DUF4131 PF13567.1 OAJ12640.1 - 0.38 10.1 1.9 0.43 9.9 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Xan_ur_permease PF00860.15 OAJ12640.1 - 0.41 9.0 4.3 0.69 8.3 3.0 1.4 1 1 0 1 1 1 0 Permease family MFS_1 PF07690.11 OAJ12640.1 - 0.72 8.5 6.8 0.78 8.3 4.7 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF1720 PF08226.6 OAJ12654.1 - 0.29 11.2 13.8 0.69 10.0 9.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) Complex1_LYR PF05347.10 OAJ12655.1 - 0.00011 21.8 3.3 0.00015 21.4 0.5 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAJ12655.1 - 0.0013 18.9 2.3 0.003 17.7 0.4 2.2 2 0 0 2 2 2 1 Complex1_LYR-like Dor1 PF04124.7 OAJ12670.1 - 0.083 11.3 5.8 0.31 9.4 0.6 2.6 3 0 0 3 3 3 0 Dor1-like family G-patch PF01585.18 OAJ12671.1 - 1.1e-05 25.0 0.2 2.3e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.3 OAJ12671.1 - 0.018 15.1 4.7 0.034 14.3 3.2 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF3449 PF11931.3 OAJ12671.1 - 0.064 12.7 0.2 0.064 12.7 0.1 2.8 5 0 0 5 5 5 0 Domain of unknown function (DUF3449) Ribosomal_60s PF00428.14 OAJ12671.1 - 0.68 10.3 0.0 0.68 10.3 0.0 3.9 1 1 1 2 2 2 0 60s Acidic ribosomal protein Secretin_N_2 PF07655.8 OAJ12672.1 - 0.4 11.1 5.9 4.5 7.7 0.1 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain DNA_pol_B PF00136.16 OAJ12689.1 - 5.8e-149 496.8 2.1 8.4e-149 496.3 1.5 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 OAJ12689.1 - 4.3e-76 255.8 0.0 5e-66 222.7 0.0 2.4 1 1 1 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 OAJ12689.1 - 7.4e-22 77.1 6.7 1.6e-21 76.0 4.7 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 OAJ12689.1 - 0.0018 17.8 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.8 OAJ12689.1 - 0.0019 16.9 2.9 0.014 14.0 0.0 2.7 3 0 0 3 3 3 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.1 OAJ12689.1 - 0.0051 16.6 0.6 0.02 14.6 0.1 2.4 2 1 0 2 2 2 1 RNase_H superfamily zf-RING-like PF08746.6 OAJ12689.1 - 0.13 12.2 5.5 0.06 13.3 0.7 2.6 2 0 0 2 2 2 0 RING-like domain DZR PF12773.2 OAJ12689.1 - 9.7 6.1 9.2 0.4 10.5 0.2 2.3 2 0 0 2 2 2 0 Double zinc ribbon Amino_oxidase PF01593.19 OAJ12690.1 - 1.5e-48 166.0 0.3 2.3e-48 165.3 0.2 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAJ12690.1 - 6.5e-12 45.2 0.5 1.5e-11 44.1 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 OAJ12690.1 - 1.2e-06 27.2 2.6 0.0029 16.1 0.7 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.19 OAJ12690.1 - 1.3e-06 27.6 1.8 1.8e-05 23.8 1.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ12690.1 - 1.6e-05 23.9 0.8 2.5e-05 23.3 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 OAJ12690.1 - 0.00015 20.9 0.2 0.00026 20.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 OAJ12690.1 - 0.00069 19.9 0.6 0.0027 18.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAJ12690.1 - 0.00073 19.6 0.6 0.27 11.2 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ12690.1 - 0.00097 18.2 0.4 0.0018 17.4 0.3 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 OAJ12690.1 - 0.0021 17.8 0.4 0.36 10.6 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAJ12690.1 - 0.0038 17.1 0.4 0.019 14.8 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAJ12690.1 - 0.011 14.7 0.3 1.9 7.2 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Methyltransf_31 PF13847.1 OAJ12706.1 - 5.2e-10 39.1 0.0 7.6e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAJ12706.1 - 1.5e-09 37.3 0.0 2e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 OAJ12706.1 - 1.2e-07 32.2 0.0 2.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ12706.1 - 2.6e-07 30.6 0.1 4.3e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ12706.1 - 4.6e-07 30.1 0.0 1.1e-06 28.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 OAJ12706.1 - 2.6e-06 27.1 0.0 3.6e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 OAJ12706.1 - 5.5e-05 22.6 0.0 7.9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 OAJ12706.1 - 0.00015 22.1 0.0 0.00028 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ12706.1 - 0.00026 20.7 0.0 0.0004 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ12706.1 - 0.00028 21.3 0.3 0.0061 17.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 OAJ12706.1 - 0.00044 19.8 0.0 0.00059 19.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.1 OAJ12706.1 - 0.0015 18.1 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 OAJ12706.1 - 0.0042 16.2 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 OAJ12706.1 - 0.014 14.5 0.1 0.023 13.9 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase UPF0020 PF01170.13 OAJ12706.1 - 0.027 14.0 0.1 0.06 12.9 0.0 1.6 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 DUF3060 PF11259.3 OAJ12706.1 - 0.043 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3060) MetW PF07021.7 OAJ12706.1 - 0.061 12.6 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.15 OAJ12706.1 - 0.068 12.1 0.0 0.094 11.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 OAJ12706.1 - 0.14 11.1 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_3 PF01596.12 OAJ12706.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase RVT_3 PF13456.1 OAJ12707.1 - 0.069 12.9 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like RVT_1 PF00078.22 OAJ12730.1 - 6.1e-19 68.2 0.0 9.9e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BCDHK_Adom3 PF10436.4 OAJ12731.1 - 3e-36 124.3 0.0 4.3e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 OAJ12731.1 - 1.3e-12 47.3 0.2 1.2e-07 31.3 0.0 3.3 3 0 0 3 3 3 3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAJ12731.1 - 2e-05 24.2 0.0 4.5e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase V-SNARE_C PF12352.3 OAJ12732.1 - 4.8e-17 61.7 3.9 1.2e-16 60.5 2.7 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 OAJ12732.1 - 0.00066 19.3 0.0 0.0021 17.7 0.0 1.9 1 0 0 1 1 1 1 Sec20 HDV_ag PF01517.13 OAJ12732.1 - 0.009 15.7 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Hepatitis delta virus delta antigen Caudo_TAP PF02413.12 OAJ12732.1 - 0.083 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein PilJ PF13675.1 OAJ12732.1 - 4.1 7.7 10.0 0.21 11.9 0.6 2.7 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Glyco_hydro_16 PF00722.16 OAJ12744.1 - 6.1e-15 54.9 2.0 9.3e-15 54.3 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_tranf_2_3 PF13641.1 OAJ12745.1 - 2.1e-19 70.2 0.5 2.9e-15 56.7 0.2 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 OAJ12745.1 - 1.9e-12 47.3 6.5 1.9e-12 47.3 4.5 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.10 OAJ12745.1 - 2.9e-11 42.4 5.9 1.4e-09 36.8 3.3 3.1 2 1 0 2 2 2 1 Chitin synthase Glyco_transf_21 PF13506.1 OAJ12745.1 - 1.7e-10 40.4 0.1 4.7e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 OAJ12745.1 - 3.3e-05 23.6 0.0 0.066 12.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 THUMP PF02926.12 OAJ12759.1 - 8.8e-14 51.5 0.1 2.3e-13 50.2 0.0 1.7 2 0 0 2 2 2 1 THUMP domain Pkinase PF00069.20 OAJ12760.1 - 2.2e-64 217.1 0.0 2.7e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ12760.1 - 4.4e-44 150.5 0.0 5.9e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ12760.1 - 1.1e-08 34.3 0.0 1.9e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ12760.1 - 7.2e-06 25.8 0.4 0.0087 15.8 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 OAJ12760.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MTP18 PF10558.4 OAJ12776.1 - 7.1e-25 87.6 0.8 7.8e-25 87.5 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) TPR_12 PF13424.1 OAJ12778.1 - 3.8e-11 42.7 16.8 0.0016 18.2 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ12778.1 - 3.5e-08 32.7 1.6 0.21 11.2 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ12778.1 - 4.4e-07 29.3 10.4 0.035 14.0 0.1 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ12778.1 - 5.4e-06 25.9 11.4 0.00092 18.8 0.0 4.7 4 0 0 4 4 4 3 TPR repeat TPR_14 PF13428.1 OAJ12778.1 - 0.0052 17.3 15.0 2.9 8.7 0.2 8.2 8 1 1 9 9 9 1 Tetratricopeptide repeat Apc3 PF12895.2 OAJ12778.1 - 0.0059 16.7 5.3 0.77 9.9 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 OAJ12778.1 - 0.013 15.2 4.1 18 5.4 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ12778.1 - 0.013 15.2 3.3 21 5.1 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Phage_term_smal PF05944.7 OAJ12778.1 - 0.039 13.6 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Phage small terminase subunit MIT PF04212.13 OAJ12778.1 - 0.13 12.1 2.3 0.21 11.4 0.2 2.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Molybdopterin PF00384.17 OAJ12795.1 - 7.9e-72 242.3 0.0 1.7e-36 125.9 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase DUF1982 PF09326.6 OAJ12795.1 - 2.6e-13 49.8 0.0 6.6e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) TPP_enzyme_M PF00205.17 OAJ12795.1 - 0.0058 16.3 0.0 1.5 8.6 0.0 2.8 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain FDF PF09532.5 OAJ12796.1 - 3.3e-08 33.9 0.0 3.3e-08 33.9 0.0 3.3 5 0 0 5 5 5 1 FDF domain SM-ATX PF14438.1 OAJ12796.1 - 0.078 12.9 0.0 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 Ataxin 2 SM domain tRNA-synt_1c PF00749.16 OAJ12810.1 - 1.5e-70 237.3 0.0 2.7e-70 236.5 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain ESSS PF10183.4 OAJ12811.1 - 4.8e-23 81.5 0.2 6.8e-23 81.0 0.2 1.3 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PHY PF00360.15 OAJ12829.1 - 1.4e-24 86.2 0.0 2.8e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 OAJ12829.1 - 1e-18 67.0 0.1 2.3e-18 65.9 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAJ12829.1 - 1.7e-13 50.5 0.0 7.7e-13 48.4 0.0 2.1 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 OAJ12829.1 - 8.1e-13 48.7 0.0 2.4e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 GAF domain HisKA PF00512.20 OAJ12829.1 - 1.1e-12 47.7 0.7 2.8e-12 46.4 0.5 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 OAJ12829.1 - 7.5e-11 42.4 0.0 1.8e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAT1 PF09770.4 OAJ12829.1 - 1.2 7.2 15.0 2.4 6.3 10.4 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 rve PF00665.21 OAJ12845.1 - 3.5e-23 81.9 0.0 7.3e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ12845.1 - 3.5e-14 52.6 0.0 8.3e-14 51.4 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 OAJ12845.1 - 4.1e-08 32.7 0.1 7.8e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.6 OAJ12845.1 - 4.4e-07 29.9 0.0 6.8e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAJ12845.1 - 0.00045 20.6 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.1 OAJ12845.1 - 0.0048 16.3 0.1 0.015 14.8 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain LANC_like PF05147.8 OAJ12845.1 - 0.54 8.7 0.0 0.84 8.1 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Retrotrans_gag PF03732.12 OAJ12846.1 - 5.7e-11 42.3 0.6 5.5e-10 39.1 0.4 2.2 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAJ12846.1 - 0.00053 19.7 0.6 0.00083 19.1 0.4 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF4473 PF14747.1 OAJ12846.1 - 0.0073 16.4 0.0 0.024 14.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4473) SPC12 PF06645.8 OAJ12862.1 - 3.2e-24 84.5 0.1 3.8e-24 84.2 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2892 PF11127.3 OAJ12862.1 - 0.00088 19.0 0.5 0.0012 18.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) rve PF00665.21 OAJ12880.1 - 6.3e-19 68.2 0.2 1.7e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Daxx PF03344.10 OAJ12880.1 - 0.0043 15.6 0.5 0.0055 15.2 0.3 1.2 1 0 0 1 1 1 1 Daxx Family rve_3 PF13683.1 OAJ12880.1 - 0.026 14.0 0.0 0.087 12.3 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain Nop14 PF04147.7 OAJ12880.1 - 3.4 5.4 11.6 5 4.9 8.0 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.22 OAJ12881.1 - 1.8e-15 56.9 0.0 3.7e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 OAJ12881.1 - 0.22 11.5 8.5 0.042 13.7 2.4 2.2 2 0 0 2 2 2 0 Zinc knuckle AA_permease_2 PF13520.1 OAJ12901.1 - 6.7e-43 146.8 21.4 8.3e-43 146.4 14.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAJ12901.1 - 1.5e-11 43.3 19.3 2e-11 42.9 13.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAJ12902.1 - 1.9e-77 260.6 34.0 2.5e-77 260.2 23.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAJ12902.1 - 2.9e-20 72.0 30.3 3.9e-20 71.6 17.9 2.0 1 1 1 2 2 2 2 Amino acid permease DUF4632 PF15451.1 OAJ12937.1 - 0.01 15.7 0.1 0.01 15.7 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4632) NUP50 PF08911.6 OAJ12937.1 - 0.25 11.7 0.0 0.25 11.7 0.0 5.9 5 2 0 5 5 5 0 NUP50 (Nucleoporin 50 kDa) NOA36 PF06524.7 OAJ12937.1 - 1.2 8.3 14.7 2.3 7.4 10.2 1.4 1 0 0 1 1 1 0 NOA36 protein Sugar_tr PF00083.19 OAJ12938.1 - 9e-64 215.6 12.5 1.1e-63 215.4 8.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ12938.1 - 7.2e-12 44.6 26.4 1.1e-11 44.1 15.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 OAJ12938.1 - 0.0011 17.5 25.7 0.014 13.8 1.4 3.6 3 1 0 4 4 4 2 MFS/sugar transport protein MMgT PF10270.4 OAJ12940.1 - 2e-20 73.1 0.0 2.3e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter TctB PF07331.6 OAJ12940.1 - 0.055 13.1 0.0 0.062 12.9 0.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family adh_short PF00106.20 OAJ12953.1 - 4.1e-19 69.0 0.6 5.8e-19 68.6 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ12953.1 - 7.5e-11 42.0 0.2 1.1e-10 41.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAJ12953.1 - 1.5e-07 31.1 0.2 3.5e-07 29.8 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 OAJ12953.1 - 0.00011 22.0 0.1 0.00062 19.5 0.1 2.0 1 1 1 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 OAJ12953.1 - 0.00074 18.4 0.1 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 OAJ12953.1 - 0.0029 17.2 1.5 0.0099 15.5 0.2 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 OAJ12953.1 - 0.16 12.4 1.2 0.52 10.7 0.5 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PI3_PI4_kinase PF00454.22 OAJ12954.1 - 3.6e-30 105.1 0.0 7.9e-30 104.0 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Cupin_8 PF13621.1 OAJ12955.1 - 3.7e-34 118.3 0.0 5e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain RVT_1 PF00078.22 OAJ12977.1 - 3.4e-32 111.5 0.0 5.8e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UCH PF00443.24 OAJ12994.1 - 6.3e-38 130.4 0.0 2.4e-36 125.2 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ12994.1 - 1.5e-11 44.3 0.0 1e-10 41.5 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ras PF00071.17 OAJ12996.1 - 3e-52 176.2 0.3 3.5e-52 176.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ12996.1 - 1.6e-18 67.3 0.0 2e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ12996.1 - 3.4e-16 58.9 0.0 4.8e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ12996.1 - 6.7e-05 22.1 0.0 8.3e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 OAJ12996.1 - 0.0002 21.3 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAJ12996.1 - 0.00028 20.4 0.1 0.0021 17.5 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 OAJ12996.1 - 0.0012 18.1 0.1 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Muskelin_N PF06588.6 OAJ13011.1 - 1e-41 142.7 0.3 6.3e-33 114.1 0.0 2.1 2 0 0 2 2 2 2 Muskelin N-terminus Kelch_3 PF13415.1 OAJ13011.1 - 3e-12 46.3 23.1 9.6e-06 25.6 0.6 8.7 8 1 0 8 8 8 4 Galactose oxidase, central domain Kelch_6 PF13964.1 OAJ13011.1 - 8.1e-12 44.7 3.2 0.033 14.3 0.0 6.9 7 0 0 7 7 7 3 Kelch motif Kelch_5 PF13854.1 OAJ13011.1 - 3.7e-11 42.7 5.8 0.0028 17.5 0.0 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 OAJ13011.1 - 2.3e-10 39.8 0.2 0.00026 20.4 0.1 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 OAJ13011.1 - 2.9e-05 23.7 19.4 0.0011 18.6 0.1 7.1 7 1 0 7 7 7 2 Galactose oxidase, central domain Kelch_2 PF07646.10 OAJ13011.1 - 0.00057 19.5 6.4 0.066 13.0 0.1 4.8 5 0 0 5 5 5 2 Kelch motif tRNA_int_endo PF01974.12 OAJ13012.1 - 4.8e-15 55.1 0.0 7.3e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Polysacc_deac_1 PF01522.16 OAJ13013.1 - 0.0011 18.5 0.1 0.0035 16.9 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide deacetylase Dimer_Tnp_hAT PF05699.9 OAJ13031.1 - 2.6e-18 65.4 0.3 5.6e-18 64.3 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-MYND PF01753.13 OAJ13031.1 - 0.018 14.9 2.5 0.039 13.8 1.7 1.6 1 0 0 1 1 1 0 MYND finger DUF4413 PF14372.1 OAJ13031.1 - 0.029 14.3 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Pkinase PF00069.20 OAJ13032.1 - 5.2e-31 107.7 0.0 2.3e-27 95.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ13032.1 - 1.1e-15 57.4 0.0 1.9e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ13032.1 - 2.1e-05 23.6 0.0 0.00012 21.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RAP1 PF07218.6 OAJ13032.1 - 0.054 11.6 0.2 0.082 10.9 0.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) APH PF01636.18 OAJ13032.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family PAG PF15347.1 OAJ13032.1 - 0.13 11.3 1.0 0.2 10.6 0.7 1.2 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Pox_ser-thr_kin PF05445.6 OAJ13032.1 - 0.21 10.3 0.0 0.3 9.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase bZIP_1 PF00170.16 OAJ13048.1 - 1.1e-05 25.2 6.8 2.3e-05 24.2 4.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAJ13048.1 - 0.00013 21.6 3.7 0.00033 20.4 2.6 1.6 1 0 0 1 1 1 1 Basic region leucine zipper LysM PF01476.15 OAJ13049.1 - 5e-12 45.5 0.0 1.7e-06 27.7 0.0 2.6 3 0 0 3 3 3 2 LysM domain RskA PF10099.4 OAJ13049.1 - 0.051 13.3 4.6 0.086 12.5 3.2 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3040 PF11239.3 OAJ13049.1 - 0.097 12.7 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF3357 PF11837.3 OAJ13049.1 - 1.2 8.9 6.8 3.1 7.6 4.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) RasGEF PF00617.14 OAJ13064.1 - 7.9e-41 139.8 0.1 1.3e-40 139.1 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 OAJ13064.1 - 1.9e-07 31.1 0.0 4.6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 OAJ13064.1 - 1.7e-05 25.3 0.0 3.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 OAJ13064.1 - 0.00011 21.6 0.0 0.00026 20.4 0.0 1.7 1 1 0 1 1 1 1 Ras family Arf PF00025.16 OAJ13064.1 - 0.006 15.8 0.0 0.015 14.5 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.18 OAJ13064.1 - 0.12 12.1 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Dynamin family Aminotran_1_2 PF00155.16 OAJ13065.1 - 2.9e-36 125.1 0.0 5.7e-36 124.2 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAJ13065.1 - 0.0031 16.7 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.2 OAJ13065.1 - 0.031 12.8 0.0 0.064 11.7 0.0 1.4 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase CMD PF02627.15 OAJ13066.1 - 0.1 12.4 0.0 0.78 9.6 0.0 2.2 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family TLD PF07534.11 OAJ13084.1 - 1.4e-24 86.6 0.0 4.6e-21 75.2 0.0 3.1 2 1 0 2 2 2 2 TLD Glyco_hydro_3 PF00933.16 OAJ13085.1 - 3.3e-49 167.4 1.6 6.6e-49 166.4 0.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 OAJ13085.1 - 0.057 12.9 0.1 0.057 12.9 0.1 2.7 3 0 0 3 3 3 0 Glycosyl hydrolase family 3 C-terminal domain SDA1 PF05285.7 OAJ13086.1 - 8.6 5.5 7.4 13 4.9 5.1 1.2 1 0 0 1 1 1 0 SDA1 DDE_3 PF13358.1 OAJ13099.1 - 1.1e-20 73.8 0.0 1.9e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 OAJ13099.1 - 1.7e-16 60.0 2.7 5.3e-16 58.4 1.9 1.9 1 0 0 1 1 1 1 Transposase rve PF00665.21 OAJ13099.1 - 0.0049 16.9 0.3 0.014 15.5 0.0 1.9 2 1 1 3 3 3 1 Integrase core domain HTH_38 PF13936.1 OAJ13099.1 - 0.009 15.5 0.8 0.53 9.8 0.0 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.1 OAJ13099.1 - 0.014 15.5 1.9 0.02 15.0 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_31 PF13560.1 OAJ13099.1 - 0.4 10.9 2.2 23 5.3 0.2 3.1 3 1 0 3 3 3 0 Helix-turn-helix domain HTH_32 PF13565.1 OAJ13099.1 - 0.91 10.3 14.1 0.29 11.9 0.4 4.0 3 1 1 4 4 4 0 Homeodomain-like domain UDPGP PF01704.13 OAJ13100.1 - 3.5e-184 612.1 0.5 4.1e-184 611.9 0.3 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase EthD PF07110.6 OAJ13101.1 - 0.00023 22.0 0.8 0.051 14.4 0.1 2.8 2 1 0 2 2 2 2 EthD domain GATase_7 PF13537.1 OAJ13102.1 - 1.3e-11 44.2 0.0 2.3e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 OAJ13102.1 - 1.1e-09 38.3 0.0 1.4e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 OAJ13102.1 - 0.012 14.4 0.0 0.082 11.5 0.0 1.9 1 1 0 1 1 1 0 Glutamine amidotransferases class-II RBD PF02196.10 OAJ13102.1 - 0.085 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain DUF3700 PF12481.3 OAJ13102.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein DUF1295 PF06966.7 OAJ13117.1 - 5.2e-41 140.4 0.8 9.3e-41 139.6 0.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 OAJ13117.1 - 0.00036 20.3 1.5 0.00073 19.3 0.1 2.1 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 OAJ13117.1 - 0.0011 18.9 0.0 0.0011 18.9 0.0 2.4 3 1 1 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.9 OAJ13117.1 - 0.012 15.8 0.0 0.034 14.3 0.0 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family FAD_binding_7 PF03441.9 OAJ13118.1 - 7.9e-90 300.8 0.0 1.2e-89 300.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 OAJ13118.1 - 9.5e-39 132.7 0.0 1.5e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase DUF4543 PF15076.1 OAJ13152.1 - 0.094 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) FA_desaturase PF00487.19 OAJ13155.1 - 1.4e-12 47.6 9.6 2.2e-12 46.9 6.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase RVT_1 PF00078.22 OAJ13176.1 - 8.8e-17 61.1 0.0 2e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ13176.1 - 1.1e-13 51.3 0.0 2.8e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ13195.1 - 5.8e-17 61.7 0.0 1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ13195.1 - 1.3e-14 54.2 0.0 4.3e-14 52.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ13195.1 - 0.0013 19.2 0.0 0.0037 17.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ13195.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_6 PF15288.1 OAJ13232.1 - 0.00079 19.0 0.4 0.0019 17.8 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 OAJ13232.1 - 0.091 12.7 0.4 0.16 11.9 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF2417 PF10329.4 OAJ13251.1 - 4.7e-14 52.3 0.0 7.3e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) DUF3951 PF13131.1 OAJ13251.1 - 1.5 8.6 0.0 1.5 8.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3951) DUF4131 PF13567.1 OAJ13251.1 - 4.1 6.7 6.8 18 4.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CLPTM1 PF05602.7 OAJ13252.1 - 2.2e-91 306.7 1.1 1.5e-89 300.7 0.5 3.0 2 1 0 2 2 2 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 OAJ13252.1 - 5.6e-09 35.4 0.9 2.2e-07 30.3 0.4 2.6 2 0 0 2 2 2 1 PQ loop repeat ECH PF00378.15 OAJ13269.1 - 1.2e-18 67.1 0.3 2.7e-17 62.7 0.2 2.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 OAJ13269.1 - 7.3e-09 35.8 0.7 0.0032 17.6 0.5 3.1 3 1 0 3 3 3 2 2-enoyl-CoA Hydratase C-terminal region PRELI PF04707.9 OAJ13270.1 - 3.4e-18 65.6 0.8 7.4e-06 25.6 0.0 3.3 2 1 1 3 3 3 3 PRELI-like family Hs1pro-1_N PF07231.7 OAJ13270.1 - 0.0019 17.8 0.1 0.0039 16.7 0.1 1.4 1 1 0 1 1 1 1 Hs1pro-1 N-terminus Pkinase PF00069.20 OAJ13271.1 - 4.6e-42 143.9 0.0 4.3e-24 85.0 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ13271.1 - 3.2e-20 72.2 0.0 2.4e-10 39.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ13271.1 - 7.3e-09 34.9 0.0 9.3e-07 28.0 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 OAJ13271.1 - 0.036 13.7 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Metallophos PF00149.23 OAJ13286.1 - 3e-41 141.0 0.1 5e-41 140.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3306 PF11748.3 OAJ13286.1 - 1.1 9.9 7.2 2.4 8.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) DUF2486 PF10667.4 OAJ13286.1 - 1.6 9.2 17.7 2.3 8.7 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) GKAP PF03359.8 OAJ13286.1 - 2.2 7.8 16.5 3.3 7.2 11.4 1.3 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein PAT1 PF09770.4 OAJ13286.1 - 7.6 4.6 32.9 10 4.2 22.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sigma70_ner PF04546.8 OAJ13287.1 - 0.0034 17.0 0.7 0.0043 16.6 0.5 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region FAM176 PF14851.1 OAJ13287.1 - 0.03 13.9 3.4 0.041 13.5 2.3 1.1 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 OAJ13287.1 - 0.19 9.7 1.9 0.21 9.6 1.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_RNA_Pol_19 PF05320.7 OAJ13287.1 - 1.5 8.5 4.9 2.1 8.0 3.4 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Apt1 PF10351.4 OAJ13287.1 - 1.5 7.5 6.7 1.8 7.3 4.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain PI3K_1B_p101 PF10486.4 OAJ13287.1 - 4.1 4.8 7.1 5.2 4.5 4.9 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Spc7_N PF15402.1 OAJ13287.1 - 5 5.0 11.7 5.8 4.7 8.1 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF2457 PF10446.4 OAJ13287.1 - 5.1 5.6 19.8 7.1 5.2 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.5 OAJ13287.1 - 6.4 5.7 7.4 7.7 5.4 5.1 1.1 1 0 0 1 1 1 0 BUD22 DUF3128 PF11326.3 OAJ13288.1 - 0.00073 19.6 0.6 0.0011 19.0 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.12 OAJ13288.1 - 0.0051 16.7 1.8 0.054 13.5 0.1 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 OAJ13288.1 - 0.007 16.3 0.8 0.01 15.8 0.5 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 OAJ13288.1 - 0.017 14.9 2.1 0.024 14.4 1.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.4 OAJ13288.1 - 0.028 14.3 1.6 0.047 13.6 1.1 1.4 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.8 OAJ13288.1 - 0.66 9.9 8.0 4 7.4 1.1 2.1 1 1 1 2 2 2 0 CHCH domain UQ_con PF00179.21 OAJ13289.1 - 2.9e-42 143.4 0.0 3.2e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ13289.1 - 0.0052 16.5 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B TipAS PF07739.8 OAJ13289.1 - 0.015 15.5 0.0 0.46 10.8 0.0 2.1 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain RWD PF05773.17 OAJ13289.1 - 0.039 13.8 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain TFIID_90kDa PF04494.10 OAJ13290.1 - 4.2e-31 107.9 0.0 9.4e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit WD40 PF00400.27 OAJ13290.1 - 3.3e-25 86.9 3.2 1.3e-10 40.6 0.1 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat LisH PF08513.6 OAJ13290.1 - 0.0085 15.8 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 LisH NUC153 PF08159.7 OAJ13305.1 - 9.1e-08 31.5 0.0 9.1e-08 31.5 0.0 3.1 3 0 0 3 3 3 1 NUC153 domain TMEM51 PF15345.1 OAJ13305.1 - 0.015 15.0 1.0 0.015 15.0 0.7 2.6 3 1 0 3 3 3 0 Transmembrane protein 51 Ank_5 PF13857.1 OAJ13308.1 - 1.1e-30 104.9 0.3 1.3e-09 37.9 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 OAJ13308.1 - 2.8e-30 102.5 0.0 8.8e-07 28.4 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 OAJ13308.1 - 1.3e-29 102.3 0.0 1.7e-21 76.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ13308.1 - 2.9e-27 94.5 0.5 1.7e-12 47.4 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ13308.1 - 1.1e-19 68.4 0.1 0.00076 19.4 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeat FYVE PF01363.16 OAJ13308.1 - 0.018 14.9 1.5 0.058 13.3 0.2 2.1 2 0 0 2 2 2 0 FYVE zinc finger CMS1 PF14617.1 OAJ13308.1 - 0.32 10.0 0.0 2 7.4 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AMP-binding PF00501.23 OAJ13328.1 - 3e-19 68.7 0.0 3.8e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Dicer_dimer PF03368.9 OAJ13329.1 - 1.2e-20 73.0 0.1 3.2e-20 71.6 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 OAJ13329.1 - 2.5e-14 52.8 0.0 5.4e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 OAJ13329.1 - 0.039 14.5 0.0 0.093 13.3 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif FXR1P_C PF12235.3 OAJ13351.1 - 1.8 8.6 18.7 0.28 11.2 8.8 2.6 2 1 1 3 3 3 0 Fragile X-related 1 protein C terminal Gp_dh_C PF02800.15 OAJ13377.1 - 8.9e-73 242.9 0.0 1.2e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 OAJ13377.1 - 4.2e-58 195.6 0.1 6.8e-58 194.9 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PalH PF08733.5 OAJ13390.1 - 0.0044 15.9 6.2 0.01 14.7 4.2 1.5 1 1 0 1 1 1 1 PalH/RIM21 His_Phos_1 PF00300.17 OAJ13391.1 - 6.1e-19 68.6 0.2 3.3e-18 66.2 0.0 2.1 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Atg14 PF10186.4 OAJ13418.1 - 0.0079 15.1 4.3 0.013 14.4 3.0 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF4218 PF13960.1 OAJ13419.1 - 0.0034 16.8 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Ytp1 PF10355.4 OAJ13447.1 - 2.2e-87 292.7 2.1 2.9e-87 292.3 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 OAJ13447.1 - 1.6e-17 62.9 0.4 1.6e-17 62.9 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Peptidase_M43 PF05572.8 OAJ13448.1 - 2.3e-13 50.0 0.0 3.7e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.1 OAJ13448.1 - 0.00075 19.0 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAJ13448.1 - 0.002 18.0 0.0 0.0042 17.0 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 OAJ13448.1 - 0.0025 18.3 0.1 0.0065 17.0 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 OAJ13448.1 - 0.017 15.1 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 OAJ13448.1 - 0.041 12.7 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.19 OAJ13448.1 - 0.054 13.2 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Matrixin Peptidase_M43 PF05572.8 OAJ13449.1 - 2e-13 50.2 0.0 3.7e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 OAJ13449.1 - 3.5e-06 27.5 0.0 6.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 OAJ13449.1 - 0.00027 21.0 0.2 0.00037 20.5 0.1 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAJ13449.1 - 0.00076 19.4 0.1 0.0014 18.5 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 OAJ13449.1 - 0.01 15.4 0.3 0.027 13.9 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 OAJ13449.1 - 0.015 15.0 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.4 OAJ13449.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M54 PF07998.6 OAJ13449.1 - 0.15 11.7 0.0 0.56 9.9 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M54 Myc_N PF01056.13 OAJ13466.1 - 0.011 14.9 1.2 0.011 14.9 0.8 2.0 2 0 0 2 2 2 0 Myc amino-terminal region DUF4350 PF14258.1 OAJ13466.1 - 0.018 15.2 0.3 0.12 12.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Nucleoplasmin PF03066.10 OAJ13466.1 - 0.05 13.1 2.3 0.093 12.2 1.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF3953 PF13129.1 OAJ13466.1 - 0.95 9.1 3.3 0.32 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) CENP-B_dimeris PF09026.5 OAJ13466.1 - 3.4 7.9 9.3 7.7 6.8 6.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Brevenin PF03032.10 OAJ13466.1 - 3.8 7.4 4.9 7.5 6.4 3.4 1.5 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family WW PF00397.21 OAJ13467.1 - 0.01 15.7 1.0 0.027 14.3 0.7 1.7 1 0 0 1 1 1 0 WW domain RNA_polI_A34 PF08208.6 OAJ13467.1 - 0.019 14.6 7.1 0.028 14.0 4.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 IncA PF04156.9 OAJ13467.1 - 0.036 13.6 0.8 0.052 13.1 0.6 1.1 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 OAJ13467.1 - 0.083 11.8 5.0 0.11 11.4 3.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ycf1 PF05758.7 OAJ13467.1 - 0.5 8.0 7.9 0.61 7.7 5.5 1.0 1 0 0 1 1 1 0 Ycf1 ATP-synt_E PF05680.7 OAJ13467.1 - 1.1 9.2 6.3 1.7 8.6 4.4 1.2 1 0 0 1 1 1 0 ATP synthase E chain Hid1 PF12722.2 OAJ13467.1 - 1.2 6.7 7.7 1.5 6.3 5.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 OAJ13467.1 - 1.3 8.0 5.1 1.9 7.4 3.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 OAJ13467.1 - 2.4 7.8 7.1 3.5 7.3 4.9 1.3 1 0 0 1 1 1 0 DDHD domain MIP-T3 PF10243.4 OAJ13467.1 - 3 6.2 24.9 4.2 5.7 17.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF572 PF04502.8 OAJ13467.1 - 3.2 6.8 20.7 4.6 6.3 14.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RPEL PF02755.10 OAJ13468.1 - 9.8e-19 66.0 8.2 8.2e-08 31.3 1.0 3.5 3 0 0 3 3 3 3 RPEL repeat MEA1 PF06910.6 OAJ13468.1 - 0.041 13.5 0.1 0.051 13.2 0.1 1.4 1 1 0 1 1 1 0 Male enhanced antigen 1 (MEA1) DUF1992 PF09350.5 OAJ13468.1 - 0.07 12.9 4.4 0.48 10.2 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1992) PilP PF04351.8 OAJ13468.1 - 0.71 9.7 5.7 2.9 7.7 1.4 2.6 1 1 2 3 3 3 0 Pilus assembly protein, PilP PPTA PF01239.17 OAJ13469.1 - 1.6e-39 131.6 3.8 1.3e-09 36.9 0.2 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.1 OAJ13469.1 - 0.0074 16.3 0.2 11 6.5 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ13469.1 - 0.04 13.5 0.9 3 7.5 0.0 3.0 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.1 OAJ13469.1 - 0.36 11.5 4.5 1.9 9.3 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DEC-1_N PF04625.8 OAJ13469.1 - 0.37 9.4 2.7 0.79 8.3 1.9 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region TPR_16 PF13432.1 OAJ13469.1 - 1 10.1 0.1 1 10.1 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF1769 PF08588.5 OAJ13484.1 - 6.9e-06 25.9 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Cys_Met_Meta_PP PF01053.15 OAJ13485.1 - 4.2e-22 77.9 0.0 2.3e-15 55.7 0.0 2.2 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 OAJ13485.1 - 0.15 11.0 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Exo_endo_phos PF03372.18 OAJ13486.1 - 3.2e-10 40.3 0.7 1.3e-09 38.3 0.1 2.3 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF4078 PF13300.1 OAJ13487.1 - 2e-16 59.8 1.3 2e-16 59.8 0.9 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) rve PF00665.21 OAJ13502.1 - 8.9e-20 70.9 0.0 2.1e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ13502.1 - 0.0004 19.8 2.2 0.0013 18.1 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain Omp28 PF11551.3 OAJ13502.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein Omp28 MULE PF10551.4 OAJ13516.1 - 0.00025 21.1 0.1 0.095 12.8 0.0 2.4 1 1 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 OAJ13516.1 - 0.0015 17.9 0.1 0.0033 16.8 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger GDNF PF02351.11 OAJ13516.1 - 0.051 14.0 1.3 0.094 13.2 0.9 1.5 1 1 0 1 1 1 0 GDNF/GAS1 domain DUF1128 PF06569.6 OAJ13516.1 - 0.058 13.1 0.1 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) CAS_CSE1 PF03378.10 OAJ13534.1 - 0.00024 19.5 0.4 0.0021 16.4 0.1 1.9 1 1 1 2 2 2 2 CAS/CSE protein, C-terminus IL22 PF14565.1 OAJ13534.1 - 0.12 12.4 0.1 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor HTH_23 PF13384.1 OAJ13573.1 - 0.011 15.4 2.1 0.16 11.6 0.0 3.7 3 1 1 4 4 4 0 Homeodomain-like domain HTH_Tnp_1 PF01527.15 OAJ13573.1 - 0.015 15.2 0.9 0.15 12.0 0.0 2.8 3 0 0 3 3 3 0 Transposase HTH_28 PF13518.1 OAJ13573.1 - 0.4 10.7 0.0 0.4 10.7 0.0 3.5 6 0 0 6 6 6 0 Helix-turn-helix domain Sec63 PF02889.11 OAJ13591.1 - 3.3e-44 151.4 0.0 4.8e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.26 OAJ13591.1 - 8.1e-10 38.4 0.0 1.8e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 OAJ13591.1 - 0.01 16.0 0.1 0.051 13.7 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain Pkinase PF00069.20 OAJ13607.1 - 9.1e-47 159.3 0.0 2.1e-32 112.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ13607.1 - 1.9e-19 69.7 0.0 1.7e-18 66.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ13607.1 - 2e-05 23.7 0.0 4.6e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAJ13607.1 - 4.2e-05 23.3 0.0 9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ13607.1 - 0.0055 15.7 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2702 PF10863.3 OAJ13626.1 - 0.032 13.9 0.4 0.085 12.5 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2702) Gly-rich_Ago1 PF12764.2 OAJ13626.1 - 1.1 9.9 6.4 2.9 8.5 4.4 1.7 1 0 0 1 1 1 0 Glycine-rich region of argonaut PBP1_TM PF14812.1 OAJ13626.1 - 2.4 8.5 8.2 1 9.7 1.1 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4218 PF13960.1 OAJ13627.1 - 2.3e-05 23.8 0.2 4.3e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) TFIIA PF03153.8 OAJ13627.1 - 0.039 13.8 3.8 0.048 13.5 2.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2339 PF10101.4 OAJ13627.1 - 2 6.6 17.0 3.1 5.9 11.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF3136 PF11334.3 OAJ13668.1 - 0.013 14.8 0.1 0.21 11.0 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3136) HeH PF12949.2 OAJ13668.1 - 0.019 14.5 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 HeH/LEM domain Prp19 PF08606.6 OAJ13708.1 - 1.9e-28 97.9 0.8 3.7e-28 97.0 0.5 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 OAJ13708.1 - 1.6e-24 84.7 2.5 2.6e-08 33.4 0.0 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat U-box PF04564.10 OAJ13708.1 - 0.00081 19.2 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 U-box domain Rtf2 PF04641.7 OAJ13708.1 - 0.0028 16.8 0.1 0.0072 15.5 0.0 1.7 2 0 0 2 2 2 1 Rtf2 RING-finger zf-Nse PF11789.3 OAJ13708.1 - 0.0057 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RibD_C PF01872.12 OAJ13709.1 - 5.6e-34 117.4 0.0 1.7e-33 115.9 0.0 1.8 2 0 0 2 2 2 1 RibD C-terminal domain Sec7 PF01369.15 OAJ13709.1 - 1.5e-29 103.0 0.0 2.3e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain Hist_deacetyl PF00850.14 OAJ13728.1 - 5.9e-90 301.7 0.0 9.3e-90 301.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 OAJ13728.1 - 0.0011 18.3 0.0 0.0071 15.7 0.0 2.1 1 1 0 1 1 1 1 Arb2 domain HTH_IclR PF09339.5 OAJ13728.1 - 0.073 12.6 0.2 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Gly_transf_sug PF04488.10 OAJ13729.1 - 2e-19 69.9 0.1 3.2e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 OAJ13729.1 - 0.00099 17.7 2.1 0.21 10.0 0.5 2.9 3 0 0 3 3 3 3 TcdA/TcdB catalytic glycosyltransferase domain SusD-like_2 PF12771.2 OAJ13729.1 - 0.084 11.2 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Starch-binding associating with outer membrane rve PF00665.21 OAJ13754.1 - 5.1e-12 45.9 0.0 1.2e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ13754.1 - 3.4e-08 33.1 0.0 0.00013 21.3 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ13754.1 - 0.035 14.6 0.0 0.087 13.3 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.15 OAJ13754.1 - 0.16 11.8 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.18 OAJ13774.1 - 0.0039 17.0 5.4 0.0082 16.0 3.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ13774.1 - 0.022 14.4 0.7 0.046 13.4 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4319 PF14203.1 OAJ13774.1 - 0.046 13.2 0.1 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) AF-4 PF05110.8 OAJ13775.1 - 0.21 9.3 15.5 0.29 8.9 10.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Collagen PF01391.13 OAJ13786.1 - 3.2e-05 23.3 12.8 4.9e-05 22.7 8.9 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Prefoldin_2 PF01920.15 OAJ13798.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Prefoldin subunit ADH_zinc_N_2 PF13602.1 OAJ13820.1 - 6.1e-17 62.7 0.4 6.9e-16 59.2 0.0 2.4 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 OAJ13820.1 - 2.2e-14 53.0 0.4 4.6e-14 52.0 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ13820.1 - 4.3e-13 48.9 0.4 1.7e-09 37.4 0.1 3.4 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain Abhydrolase_6 PF12697.2 OAJ13821.1 - 7.7e-09 35.7 0.6 1.3e-08 35.0 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ13821.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family PIN_4 PF13638.1 OAJ13822.1 - 1.3e-10 41.5 0.0 4.1e-09 36.6 0.0 2.3 1 1 0 1 1 1 1 PIN domain Pkinase PF00069.20 OAJ13839.1 - 6.5e-33 113.9 0.0 3e-32 111.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ13839.1 - 4.6e-09 35.7 0.0 1.9e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ13839.1 - 0.15 10.9 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ABC2_membrane PF01061.19 OAJ13856.1 - 6.1e-30 103.9 17.0 8.4e-30 103.5 11.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 OAJ13856.1 - 8.3e-26 90.9 0.1 1.4e-25 90.1 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 OAJ13856.1 - 8.6e-09 35.7 0.1 0.0043 17.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAJ13856.1 - 2.2e-05 23.9 0.3 0.02 14.3 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 OAJ13856.1 - 5.5e-05 22.3 0.0 0.013 14.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 OAJ13856.1 - 6.6e-05 23.0 0.2 0.00047 20.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 OAJ13856.1 - 0.00011 21.6 0.9 0.00075 18.9 0.3 2.5 2 1 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ13856.1 - 0.00014 21.8 0.3 0.0004 20.4 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 OAJ13856.1 - 0.0015 17.6 0.1 0.0026 16.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 OAJ13856.1 - 0.0088 15.7 0.4 0.024 14.3 0.3 1.8 1 1 0 1 1 1 1 Part of AAA domain AAA_23 PF13476.1 OAJ13856.1 - 0.0096 16.2 0.1 0.015 15.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 OAJ13856.1 - 0.014 14.8 0.1 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 OAJ13856.1 - 0.03 14.1 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 OAJ13856.1 - 0.075 13.8 0.0 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 OAJ13856.1 - 0.11 11.3 0.1 0.24 10.2 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 OAJ13856.1 - 0.11 12.1 0.2 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 OAJ13856.1 - 0.13 12.0 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 OAJ13856.1 - 0.24 11.0 0.0 0.55 9.8 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 OAJ13856.1 - 0.63 9.9 2.3 0.54 10.2 0.3 1.8 2 0 0 2 2 2 0 AAA domain FAD_binding_8 PF08022.7 OAJ13857.1 - 2e-19 69.4 0.0 5.3e-19 68.0 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 OAJ13857.1 - 2.1e-14 53.7 0.0 2.6e-13 50.1 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 OAJ13857.1 - 3.4e-09 36.8 4.2 8e-09 35.6 2.9 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 OAJ13857.1 - 0.00044 20.3 0.0 0.0017 18.4 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain DUF2119 PF09892.4 OAJ13857.1 - 0.22 10.7 0.0 4.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2119) Adaptin_N PF01602.15 OAJ13870.1 - 3.2e-100 335.9 11.1 5.2e-100 335.2 7.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 OAJ13870.1 - 2.1e-66 221.5 0.0 5.8e-66 220.1 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 OAJ13870.1 - 5.7e-62 207.5 0.1 1.4e-61 206.2 0.1 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 OAJ13870.1 - 3.6e-13 49.5 8.7 0.00032 20.9 0.0 5.6 3 1 1 5 5 5 3 HEAT repeats Cnd1 PF12717.2 OAJ13870.1 - 6.3e-10 39.1 7.9 0.0044 16.8 0.0 5.1 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 OAJ13870.1 - 5.1e-07 29.2 0.2 0.0068 16.4 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 OAJ13870.1 - 0.00015 22.0 0.5 1.5 9.3 0.0 4.3 3 0 0 3 3 3 2 HEAT-like repeat Cullin PF00888.17 OAJ13870.1 - 0.001 17.6 1.1 0.0034 15.9 0.2 2.0 2 0 0 2 2 2 1 Cullin family ParcG PF10274.4 OAJ13870.1 - 0.02 14.8 0.8 0.82 9.5 0.0 2.7 2 1 0 2 2 2 0 Parkin co-regulated protein DUF3810 PF12725.2 OAJ13870.1 - 0.075 11.9 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Arm PF00514.18 OAJ13870.1 - 0.86 9.5 3.9 81 3.2 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Peptidase_S9 PF00326.16 OAJ13871.1 - 3e-38 131.2 0.0 4.7e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAJ13871.1 - 2e-10 40.5 0.4 6.4e-10 38.9 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ13871.1 - 3.1e-06 27.2 3.6 1e-05 25.5 2.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 OAJ13871.1 - 0.00017 20.8 0.1 0.00033 19.9 0.1 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.15 OAJ13871.1 - 0.001 18.5 0.4 0.0041 16.5 0.2 2.0 2 1 0 2 2 2 1 Putative esterase AXE1 PF05448.7 OAJ13871.1 - 0.0085 14.6 0.4 0.78 8.1 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) PD40 PF07676.7 OAJ13871.1 - 0.069 12.8 0.8 0.48 10.1 0.0 2.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat COesterase PF00135.23 OAJ13871.1 - 0.59 8.7 3.6 0.77 8.3 1.5 1.9 2 1 0 2 2 2 0 Carboxylesterase family Dabb PF07876.7 OAJ13872.1 - 6.2e-15 55.4 0.1 7.1e-15 55.2 0.1 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Hep_59 PF07052.6 OAJ13893.1 - 1.9e-26 92.4 0.6 1.9e-26 92.4 0.4 2.9 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 ABC_tran PF00005.22 OAJ13894.1 - 7.6e-36 123.4 0.1 6.8e-18 65.2 0.0 3.1 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 OAJ13894.1 - 8.8e-15 54.0 5.8 2.2e-14 52.7 4.0 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 OAJ13894.1 - 3.9e-14 53.3 5.7 8.4e-05 22.6 0.9 4.2 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 OAJ13894.1 - 1.1e-09 37.8 4.9 0.00059 19.1 0.5 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 OAJ13894.1 - 2.2e-07 30.1 3.3 2.2e-07 30.1 2.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.1 OAJ13894.1 - 1.5e-06 27.5 0.2 4.1 6.3 0.0 4.4 5 0 0 5 5 4 0 AAA ATPase domain DUF258 PF03193.11 OAJ13894.1 - 5.2e-06 25.7 0.8 0.12 11.5 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 OAJ13894.1 - 6.8e-06 26.2 0.2 0.0044 17.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 OAJ13894.1 - 8e-06 26.0 0.0 0.032 14.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 OAJ13894.1 - 1.4e-05 24.4 0.2 0.039 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain VirE PF05272.6 OAJ13894.1 - 7.3e-05 22.3 0.0 0.41 10.0 0.0 2.4 2 0 0 2 2 2 2 Virulence-associated protein E Fer4_6 PF12837.2 OAJ13894.1 - 8.2e-05 22.3 2.4 8.2e-05 22.3 1.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.2 OAJ13894.1 - 0.0001 22.5 8.4 0.00049 20.4 0.2 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_23 PF13476.1 OAJ13894.1 - 0.00025 21.4 4.9 0.0056 17.0 0.2 2.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 OAJ13894.1 - 0.00027 20.6 1.3 0.031 13.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 OAJ13894.1 - 0.00034 21.0 0.4 0.54 10.7 0.0 3.0 2 1 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 OAJ13894.1 - 0.0004 20.4 0.0 0.058 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 OAJ13894.1 - 0.00047 19.6 0.1 0.39 10.1 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 OAJ13894.1 - 0.00067 19.5 0.2 0.12 12.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 OAJ13894.1 - 0.00072 19.8 0.3 0.51 10.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 OAJ13894.1 - 0.00088 19.1 0.0 1.3 9.0 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 OAJ13894.1 - 0.00095 19.9 2.9 1.2 9.9 0.1 2.9 2 2 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 OAJ13894.1 - 0.0014 18.8 0.0 0.33 11.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase MobB PF03205.9 OAJ13894.1 - 0.0017 18.0 0.7 0.31 10.7 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_2 PF12797.2 OAJ13894.1 - 0.002 17.9 2.7 0.002 17.9 1.9 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain SRP54 PF00448.17 OAJ13894.1 - 0.002 17.6 1.3 0.23 10.8 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain UPF0079 PF02367.12 OAJ13894.1 - 0.0032 17.1 0.2 0.052 13.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_21 PF14697.1 OAJ13894.1 - 0.0034 17.2 13.0 0.0082 15.9 9.0 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 OAJ13894.1 - 0.0051 16.5 1.9 0.0051 16.5 1.3 2.3 1 1 1 2 2 2 1 4Fe-4S dicluster domain AAA_28 PF13521.1 OAJ13894.1 - 0.0059 16.5 0.3 1.4 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 OAJ13894.1 - 0.0064 15.3 0.0 0.27 10.0 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Fer4_16 PF13484.1 OAJ13894.1 - 0.009 16.7 0.2 0.009 16.7 0.1 2.5 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain AAA_14 PF13173.1 OAJ13894.1 - 0.0094 15.8 0.3 6.5 6.6 0.0 3.1 2 1 1 3 3 2 0 AAA domain Fer4_9 PF13187.1 OAJ13894.1 - 0.01 16.1 2.3 0.01 16.1 1.6 2.3 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 OAJ13894.1 - 0.023 14.7 1.4 0.023 14.7 1.0 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_24 PF13479.1 OAJ13894.1 - 0.041 13.4 0.2 1.7 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 OAJ13894.1 - 0.048 13.0 0.1 6.8 6.0 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Fer4_17 PF13534.1 OAJ13894.1 - 0.053 13.8 0.2 0.053 13.8 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_10 PF12846.2 OAJ13894.1 - 0.077 12.4 0.8 4.8 6.5 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain Rad17 PF03215.10 OAJ13894.1 - 0.089 11.4 0.0 1.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 OAJ13894.1 - 0.18 11.5 0.9 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Fer4_4 PF12800.2 OAJ13894.1 - 0.43 11.0 13.2 0.071 13.4 1.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.2 OAJ13894.1 - 5.7 7.7 13.5 0.11 13.0 2.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain LSM PF01423.17 OAJ13895.1 - 1.8e-09 36.9 0.0 3.4e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 LSM domain RrnaAD PF00398.15 OAJ13896.1 - 0.00019 20.5 0.0 0.00026 20.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase AT_hook PF02178.14 OAJ13896.1 - 0.0011 18.3 16.7 0.04 13.5 2.8 2.7 2 0 0 2 2 2 2 AT hook motif Glyco_hydro_63 PF03200.11 OAJ13913.1 - 2.3e-09 35.6 1.7 8.7e-08 30.5 0.2 3.3 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase Methyltransf_16 PF10294.4 OAJ13913.1 - 2.3e-08 33.7 0.0 0.0018 17.7 0.0 2.4 2 0 0 2 2 2 2 Putative methyltransferase UDPGT PF00201.13 OAJ13913.1 - 0.73 8.3 0.0 1.1 7.6 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Exo_endo_phos PF03372.18 OAJ13931.1 - 2.2e-12 47.4 0.3 1.6e-11 44.6 0.2 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peripla_BP_2 PF01497.13 OAJ13931.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein TPR_11 PF13414.1 OAJ13932.1 - 1.8e-36 123.5 50.3 5.3e-10 38.8 1.9 13.3 10 5 3 13 13 13 10 TPR repeat TPR_1 PF00515.23 OAJ13932.1 - 4.6e-29 98.8 29.6 3.6e-05 23.1 0.2 13.9 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ13932.1 - 2.5e-25 86.2 9.0 0.0061 16.2 0.0 12.9 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ13932.1 - 2e-24 83.4 71.5 0.00011 21.8 1.0 18.9 20 0 0 20 20 19 6 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ13932.1 - 4.6e-23 79.6 92.8 2.1e-05 24.7 0.2 20.1 14 4 6 20 20 20 7 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ13932.1 - 1.2e-20 73.5 126.1 5.7e-06 26.8 1.4 19.5 14 6 6 21 21 20 7 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ13932.1 - 3.9e-20 70.3 27.6 0.0025 17.8 0.1 14.8 18 0 0 18 18 17 4 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ13932.1 - 7.1e-19 67.5 62.6 6.2e-09 35.6 1.3 13.9 10 6 4 14 14 13 5 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ13932.1 - 6.6e-11 42.3 69.5 0.00058 20.1 0.3 12.5 11 4 2 13 13 12 5 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ13932.1 - 8.4e-10 38.4 33.7 0.02 15.3 0.0 13.6 14 0 0 14 14 13 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ13932.1 - 5.5e-09 35.1 30.7 0.13 12.1 0.0 11.4 10 0 0 10 10 10 4 Tetratricopeptide repeat Apc3 PF12895.2 OAJ13932.1 - 4.4e-06 26.7 22.9 0.0017 18.4 0.4 8.3 9 0 0 9 9 9 2 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 OAJ13932.1 - 0.025 13.9 3.7 4.5 6.6 0.1 4.5 3 2 0 3 3 3 0 26S proteasome subunit RPN7 TPR_9 PF13371.1 OAJ13932.1 - 0.16 11.8 51.4 1.1 9.1 0.8 12.0 10 2 2 12 12 11 0 Tetratricopeptide repeat ChAPs PF09295.5 OAJ13932.1 - 0.28 9.8 3.7 6.6 5.3 0.0 3.0 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.1 OAJ13932.1 - 0.78 9.9 40.6 0.87 9.7 0.7 8.5 6 3 1 9 9 8 0 Tetratricopeptide repeat zf-SNAP50_C PF12251.3 OAJ13950.1 - 1.1e-08 34.7 0.0 3.1e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal KCl_Cotrans_1 PF03522.10 OAJ13950.1 - 2.7 7.5 5.9 0.31 10.5 0.5 2.2 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) SMC_Nse1 PF07574.8 OAJ13951.1 - 3.9e-20 72.3 0.0 4.4e-11 42.7 0.0 2.2 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 OAJ13951.1 - 0.0016 18.3 8.0 0.0036 17.2 5.6 1.6 1 0 0 1 1 1 1 RING-like domain Myc_N PF01056.13 OAJ13951.1 - 0.004 16.3 3.5 0.0059 15.8 2.5 1.3 1 0 0 1 1 1 1 Myc amino-terminal region BSP_II PF05432.6 OAJ13951.1 - 0.0048 16.2 13.2 0.0069 15.7 9.2 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Pox_Ag35 PF03286.9 OAJ13951.1 - 0.31 10.5 6.5 0.55 9.7 4.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sigma70_ner PF04546.8 OAJ13951.1 - 0.75 9.3 7.7 1.5 8.3 5.4 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region FANCL_C PF11793.3 OAJ13951.1 - 1.5 8.8 5.5 6.5 6.7 3.4 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain PBP1_TM PF14812.1 OAJ13951.1 - 3.8 7.8 21.1 0.81 10.0 9.6 2.9 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UBN2 PF14223.1 OAJ13952.1 - 9.9e-06 25.3 0.1 4.7e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ13952.1 - 4.1e-05 23.3 2.1 9.9e-05 22.0 1.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 OAJ13952.1 - 0.02 14.3 0.6 0.059 12.8 0.4 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.1 OAJ13952.1 - 0.021 14.2 0.2 0.057 12.9 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF1110 PF06533.7 OAJ13952.1 - 0.071 12.9 0.4 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1110) MSP1b PF03429.8 OAJ13971.1 - 0.073 10.9 0.0 0.097 10.5 0.0 1.1 1 0 0 1 1 1 0 Major surface protein 1B RWD PF05773.17 OAJ13973.1 - 4.8e-19 68.3 0.2 7.6e-19 67.6 0.1 1.3 1 0 0 1 1 1 1 RWD domain TFIIA PF03153.8 OAJ13973.1 - 0.054 13.3 3.6 0.06 13.2 2.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3410 PF11890.3 OAJ13973.1 - 0.24 11.0 2.6 15 5.3 0.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3410) OmpH PF03938.9 OAJ13973.1 - 4.6 7.1 12.1 0.68 9.8 1.5 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Frag1 PF10277.4 OAJ13974.1 - 3.4e-26 92.0 18.2 3.9e-26 91.8 12.6 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF1345 PF07077.6 OAJ13974.1 - 0.0051 16.3 5.2 0.05 13.1 0.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1345) Git3 PF11710.3 OAJ13974.1 - 0.37 10.3 12.5 0.5 9.9 0.0 3.0 3 1 1 4 4 4 0 G protein-coupled glucose receptor regulating Gpa2 Glyco_hydro_45 PF02015.11 OAJ13993.1 - 3.3e-13 50.1 2.0 4.3e-13 49.8 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 DUF3302 PF11742.3 OAJ13993.1 - 0.24 11.3 0.8 0.43 10.4 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3302) Colipase PF01114.13 OAJ13993.1 - 2.7 7.5 5.6 0.23 10.9 0.4 1.7 2 0 0 2 2 2 0 Colipase, N-terminal domain Glyco_hydro_45 PF02015.11 OAJ13995.1 - 1.7e-49 168.6 8.5 1.9e-49 168.4 5.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 NIPSNAP PF07978.8 OAJ14030.1 - 1.4e-35 121.3 2.5 5.5e-28 96.9 0.2 2.2 2 0 0 2 2 2 2 NIPSNAP DUF718 PF05336.8 OAJ14030.1 - 0.012 15.4 1.6 0.013 15.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF718) TFIIF_alpha PF05793.7 OAJ14032.1 - 0.019 13.3 2.5 0.023 13.0 1.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Spt5_N PF11942.3 OAJ14032.1 - 0.035 14.7 4.0 0.035 14.7 2.8 1.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF445 PF04286.7 OAJ14032.1 - 0.038 13.5 0.0 0.044 13.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Glyco_hydro_85 PF03644.8 OAJ14033.1 - 4.6e-53 180.3 0.0 6.3e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Acyl-CoA_dh_1 PF00441.19 OAJ14034.1 - 0.11 12.6 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain zf-H2C2_2 PF13465.1 OAJ14073.1 - 8.2e-06 25.8 3.3 8.2e-06 25.8 2.3 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ14073.1 - 0.00042 20.5 20.5 0.0012 19.0 1.4 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ14073.1 - 0.0044 17.2 18.7 0.0067 16.6 1.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger CRISPR_Cse2 PF09485.5 OAJ14092.1 - 1.5 8.8 11.3 27 4.7 7.2 3.0 2 1 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Peptidase_M50B PF13398.1 OAJ14114.1 - 1.8e-54 184.1 15.4 2.3e-54 183.8 10.7 1.1 1 0 0 1 1 1 1 Peptidase M50B-like HATPase_c PF02518.21 OAJ14115.1 - 3e-30 104.1 0.7 8.6e-30 102.7 0.0 2.2 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAJ14115.1 - 7e-25 87.2 0.1 3.7e-24 84.8 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 OAJ14115.1 - 3.6e-20 71.7 0.1 1.2e-19 69.9 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 OAJ14115.1 - 2.2e-18 66.1 0.4 2.2e-18 66.1 0.3 2.3 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.1 OAJ14115.1 - 9.4e-17 61.3 0.0 2.5e-12 47.0 0.0 4.3 4 1 0 4 4 4 2 PAS domain PAS_4 PF08448.5 OAJ14115.1 - 2.2e-16 59.8 1.0 2e-07 30.9 0.0 4.8 4 0 0 4 4 4 3 PAS fold PAS PF00989.19 OAJ14115.1 - 6e-11 42.1 0.0 0.011 15.4 0.0 4.6 4 0 0 4 4 4 2 PAS fold HATPase_c_3 PF13589.1 OAJ14115.1 - 0.001 18.7 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.1 OAJ14115.1 - 0.2 11.9 0.0 8.3 6.7 0.0 3.1 3 0 0 3 3 3 0 PAS domain DUF605 PF04652.11 OAJ14175.1 - 0.00011 21.8 7.7 0.00011 21.8 5.3 1.8 2 0 0 2 2 2 1 Vta1 like WH2 PF02205.15 OAJ14175.1 - 0.00083 18.8 0.1 0.0019 17.7 0.1 1.7 1 0 0 1 1 1 1 WH2 motif EFG_C PF00679.19 OAJ14175.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Elongation factor G C-terminus F-box-like PF12937.2 OAJ14176.1 - 3.3e-09 36.3 0.3 7.3e-09 35.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ14176.1 - 7.2e-09 35.0 0.3 1.7e-08 33.9 0.2 1.7 1 0 0 1 1 1 1 F-box domain DUF1034 PF06280.7 OAJ14177.1 - 6.7e-08 32.9 0.0 1.3e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) zf-DHHC PF01529.15 OAJ14196.1 - 1e-33 116.1 7.7 1.6e-33 115.5 5.3 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_2 PF12796.2 OAJ14196.1 - 4.2e-33 113.5 3.1 3.6e-11 43.2 0.0 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ14196.1 - 1.7e-28 96.9 11.6 1.6e-07 30.7 0.1 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 OAJ14196.1 - 1.3e-26 92.4 4.9 1.3e-10 41.5 0.1 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ14196.1 - 2.3e-21 75.3 7.5 4.2e-06 26.8 0.1 6.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ14196.1 - 2e-18 64.6 3.3 0.00045 20.1 0.0 6.2 5 0 0 5 5 5 4 Ankyrin repeat DUF1843 PF08898.5 OAJ14196.1 - 3.7 7.6 10.4 6.6 6.8 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) PrgI PF12666.2 OAJ14196.1 - 6 7.0 5.8 2.2 8.4 0.8 2.4 2 0 0 2 2 2 0 PrgI family protein Pet127 PF08634.5 OAJ14197.1 - 4.3e-104 347.5 0.1 5.7e-104 347.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 rve PF00665.21 OAJ14219.1 - 2e-07 31.1 0.0 7.3e-07 29.3 0.0 2.0 2 1 0 2 2 2 1 Integrase core domain CPSase_L_D3 PF02787.14 OAJ14219.1 - 0.004 16.9 0.0 0.0087 15.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_23 PF13384.1 OAJ14219.1 - 0.0048 16.5 0.0 0.024 14.2 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain zf-C2HC_2 PF13913.1 OAJ14220.1 - 0.073 12.7 0.3 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type CcmD PF04995.9 OAJ14244.1 - 0.11 12.2 0.5 0.22 11.2 0.3 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) WD40 PF00400.27 OAJ14245.1 - 2.7e-43 144.3 10.4 2.5e-10 39.8 0.0 7.2 7 1 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 OAJ14245.1 - 0.001 18.5 0.1 0.0092 15.4 0.0 2.4 2 1 1 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.11 OAJ14245.1 - 0.0056 15.0 0.0 1.1 7.4 0.0 2.6 2 1 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 OAJ14245.1 - 0.065 11.3 0.9 1.7 6.6 0.6 2.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 LRR_7 PF13504.1 OAJ14267.1 - 0.00077 19.2 2.6 4.7 7.8 0.0 5.7 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 OAJ14267.1 - 0.0011 18.7 5.3 6.4 7.1 0.0 5.9 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.2 OAJ14267.1 - 0.015 14.8 0.3 18 5.1 0.0 4.6 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 OAJ14267.1 - 0.34 11.1 9.9 0.81 9.9 0.0 5.2 5 1 1 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.1 OAJ14267.1 - 0.4 10.4 8.3 4.2 7.1 0.0 4.4 4 2 0 4 4 4 0 Leucine rich repeat Polysacc_deac_1 PF01522.16 OAJ14268.1 - 1.2e-23 83.0 0.0 1.9e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase GST_N PF02798.15 OAJ14269.1 - 8.4e-11 41.8 0.0 1.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 OAJ14269.1 - 1.4e-10 41.2 0.0 2.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ14269.1 - 2.7e-10 40.0 0.0 4.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ14269.1 - 8.8e-09 35.2 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ14269.1 - 1.4e-08 34.5 0.1 2.6e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ14269.1 - 2.9e-06 27.6 0.1 4.8e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3220 PF11516.3 OAJ14269.1 - 0.094 12.6 0.1 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) RRM_1 PF00076.17 OAJ14292.1 - 7.8e-33 111.9 0.0 2.3e-17 62.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ14292.1 - 8.3e-22 76.9 0.0 9.5e-10 38.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ14292.1 - 1.7e-17 62.9 0.0 2.4e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 OAJ14292.1 - 0.067 12.7 0.2 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Ribonuclease B OB domain cwf18 PF08315.7 OAJ14293.1 - 7.2e-26 91.1 6.9 9.6e-26 90.7 4.8 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor SCP1201-deam PF14428.1 OAJ14293.1 - 0.13 11.9 0.2 0.29 10.8 0.0 1.7 2 1 0 2 2 2 0 SCP1.201-like deaminase SNF5 PF04855.7 OAJ14294.1 - 2.7e-18 66.3 0.0 2.7e-18 66.3 0.0 3.8 3 1 0 3 3 3 1 SNF5 / SMARCB1 / INI1 Proteasome PF00227.21 OAJ14295.1 - 1.3e-32 112.6 0.0 1.7e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit NTP_transf_2 PF01909.18 OAJ14325.1 - 1.7e-05 25.0 0.0 4.4e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyltransferase domain MatP PF06303.7 OAJ14326.1 - 1 9.2 7.9 3 7.7 0.5 2.5 1 1 1 2 2 2 0 Organiser of macrodomain of Terminus of chromosome IncA PF04156.9 OAJ14326.1 - 1.1 8.7 15.7 1.9 8.0 10.9 1.5 1 1 0 1 1 1 0 IncA protein PGA_cap PF09587.5 OAJ14326.1 - 2 7.7 5.9 0.22 10.8 1.2 1.5 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap DUF1664 PF07889.7 OAJ14326.1 - 6.5 6.5 7.0 11 5.8 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Daxx PF03344.10 OAJ14365.1 - 0.71 8.2 17.8 0.004 15.7 5.2 2.0 2 0 0 2 2 2 0 Daxx Family DUF3153 PF11353.3 OAJ14365.1 - 1.1 8.6 4.8 0.28 10.6 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) GATase_2 PF00310.16 OAJ14369.1 - 1.8e-09 36.7 0.1 2.4e-09 36.3 0.1 1.3 1 1 0 1 1 1 1 Glutamine amidotransferases class-II Kazal_2 PF07648.10 OAJ14369.1 - 0.025 14.5 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain SIS PF01380.17 OAJ14369.1 - 0.071 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 SIS domain Kinesin PF00225.18 OAJ14391.1 - 1.2e-97 326.6 5.5 1.6e-52 178.2 0.0 4.1 4 0 0 4 4 4 2 Kinesin motor domain Spc7 PF08317.6 OAJ14391.1 - 5.2e-05 22.0 8.4 5.2e-05 22.0 5.8 11.5 6 2 4 12 12 12 6 Spc7 kinetochore protein ADH_zinc_N_2 PF13602.1 OAJ14408.1 - 1.1e-16 61.8 0.0 2.3e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 OAJ14408.1 - 1.5e-14 53.6 0.0 2.9e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DeoRC PF00455.17 OAJ14408.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 DeoR C terminal sensor domain ADH_N PF08240.7 OAJ14408.1 - 0.02 14.6 0.0 0.089 12.5 0.0 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain His_biosynth PF00977.16 OAJ14410.1 - 4.4e-34 117.7 0.0 5.7e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 OAJ14410.1 - 0.037 13.1 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family SnoaL_2 PF12680.2 OAJ14450.1 - 0.074 13.4 0.0 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 SnoaL-like domain LtrA PF06772.6 OAJ14451.1 - 5.8e-17 61.6 22.1 4.4e-09 35.7 0.3 2.4 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Retrotrans_gag PF03732.12 OAJ14473.1 - 0.043 13.8 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.22 OAJ14474.1 - 7.5e-17 61.4 0.0 1.6e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ14474.1 - 0.0012 19.2 0.0 0.003 18.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ14474.1 - 0.012 15.3 0.3 0.038 13.8 0.0 1.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ14474.1 - 0.036 13.9 0.0 0.09 12.7 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.21 OAJ14477.1 - 6.9e-14 51.9 0.0 1.2e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Ubiq_cyt_C_chap PF03981.7 OAJ14500.1 - 2.2e-29 102.0 0.1 1.2e-25 90.0 0.0 2.3 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone Aminotran_1_2 PF00155.16 OAJ14501.1 - 1.2e-43 149.4 0.0 5.1e-43 147.4 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Gpi16 PF04113.9 OAJ14502.1 - 2.7e-91 306.2 0.0 3.2e-41 141.0 0.0 4.3 3 1 0 3 3 3 3 Gpi16 subunit, GPI transamidase component DUF3283 PF11686.3 OAJ14502.1 - 0.21 11.3 0.0 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) GalP_UDP_transf PF01087.17 OAJ14525.1 - 2.8e-60 203.5 0.2 4.1e-60 202.9 0.1 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 OAJ14525.1 - 1.3e-39 135.4 0.0 4.5e-20 71.8 0.0 2.6 3 0 0 3 3 3 2 Galactose-1-phosphate uridyl transferase, C-terminal domain Rpn3_C PF08375.6 OAJ14526.1 - 4.6e-23 81.4 1.0 9.5e-23 80.3 0.7 1.5 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 OAJ14526.1 - 5e-18 65.3 0.2 9.8e-18 64.4 0.1 1.5 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 OAJ14526.1 - 0.0011 18.7 0.1 0.0018 18.0 0.1 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 WD40 PF00400.27 OAJ14527.1 - 5e-09 35.6 2.0 0.38 10.7 0.0 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat AT_hook PF02178.14 OAJ14527.1 - 0.0007 18.9 90.4 1.9 8.4 4.7 8.5 7 0 0 7 7 7 7 AT hook motif SSB PF00436.20 OAJ14528.1 - 1.3e-14 53.8 0.0 1.7e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family ParA PF10609.4 OAJ14557.1 - 1.4e-25 88.9 0.0 2.4e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 OAJ14557.1 - 1e-14 54.3 0.2 8.8e-14 51.3 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 OAJ14557.1 - 9e-07 28.9 0.1 2.4e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ14557.1 - 0.00039 20.1 1.6 0.47 10.2 0.1 2.6 3 0 0 3 3 3 2 Part of AAA domain AAA_25 PF13481.1 OAJ14557.1 - 0.00099 18.5 0.0 0.003 16.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 OAJ14557.1 - 0.0023 17.0 0.0 0.016 14.2 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_26 PF13500.1 OAJ14557.1 - 0.0076 15.8 0.1 0.62 9.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 OAJ14557.1 - 0.054 12.5 0.8 0.26 10.2 0.1 2.2 2 1 1 3 3 3 0 Anion-transporting ATPase Fer4_NifH PF00142.13 OAJ14557.1 - 0.063 12.4 0.1 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family YadA_anchor PF03895.10 OAJ14558.1 - 0.84 9.6 13.1 0.33 10.9 1.9 3.7 3 0 0 3 3 3 0 YadA-like C-terminal region WND PF07861.6 OAJ14578.1 - 0.01 14.9 0.5 0.014 14.4 0.4 1.2 1 0 0 1 1 1 0 WisP family N-Terminal Region DUF1183 PF06682.7 OAJ14578.1 - 0.075 12.6 0.1 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Cutinase PF01083.17 OAJ14580.1 - 7.2e-28 97.5 0.0 9.2e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ14580.1 - 4.3e-05 23.1 0.0 5.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ14580.1 - 0.0075 16.1 0.0 0.0096 15.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 OAJ14580.1 - 0.013 15.7 0.0 0.018 15.2 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain PE-PPE PF08237.6 OAJ14580.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain WD40 PF00400.27 OAJ14581.1 - 1.8e-22 78.2 16.5 1.1e-05 25.0 0.5 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 OAJ14581.1 - 0.095 12.3 0.0 3.1 7.4 0.0 2.6 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nucleo_P87 PF07267.6 OAJ14581.1 - 6.9 5.2 6.9 14 4.2 4.8 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pro_isomerase PF00160.16 OAJ14603.1 - 1.3e-43 148.9 0.1 1.4e-43 148.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Choline_transpo PF04515.7 OAJ14604.1 - 6.1e-86 288.1 23.6 6.1e-86 288.1 16.4 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.8 OAJ14604.1 - 0.028 14.4 0.9 0.083 12.9 0.6 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1418 PF07214.7 OAJ14604.1 - 0.19 11.3 1.3 0.69 9.5 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) HSF_DNA-bind PF00447.12 OAJ14605.1 - 6.7e-20 71.2 0.0 1e-18 67.4 0.0 2.2 1 1 0 1 1 1 1 HSF-type DNA-binding Docking PF08990.6 OAJ14622.1 - 0.28 10.4 3.5 0.68 9.2 2.4 1.6 1 0 0 1 1 1 0 Erythronolide synthase docking Sld5 PF05916.6 OAJ14623.1 - 8.7e-18 64.6 0.5 1.6e-17 63.7 0.0 1.6 2 0 0 2 2 2 1 GINS complex protein DSPn PF14671.1 OAJ14624.1 - 3.7e-31 108.0 0.0 2.8e-30 105.1 0.0 2.1 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 OAJ14624.1 - 3.4e-13 49.3 0.0 7.1e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAJ14624.1 - 2.1e-05 23.9 0.0 4.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 OAJ14624.1 - 0.0041 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate zf-RING_2 PF13639.1 OAJ14650.1 - 3.8e-08 33.0 11.9 5.9e-08 32.4 8.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAJ14650.1 - 8.7e-06 25.7 3.3 1.5e-05 25.0 2.3 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 OAJ14650.1 - 2.2e-05 24.0 9.7 3.5e-05 23.3 6.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ14650.1 - 0.00025 21.0 12.6 0.00038 20.4 8.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ14650.1 - 0.009 15.7 10.4 0.014 15.1 7.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 OAJ14650.1 - 2.1 8.1 10.5 3.1 7.5 7.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CRCB PF02537.10 OAJ14651.1 - 2.9e-22 78.7 17.5 6e-15 55.1 3.8 2.6 2 0 0 2 2 2 2 CrcB-like protein Aldedh PF00171.17 OAJ14652.1 - 3.4e-146 487.2 0.3 3.9e-146 487.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Chitin_synth_1 PF01644.12 OAJ14674.1 - 2.1e-69 232.5 1.7 3.1e-69 231.9 1.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 OAJ14674.1 - 3.1e-22 78.6 0.1 2.6e-18 65.7 0.0 2.6 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 OAJ14674.1 - 4.6e-20 71.1 0.1 8.4e-20 70.2 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 OAJ14674.1 - 1.8e-08 34.3 0.4 1.8e-08 34.3 0.3 2.8 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ14674.1 - 6.7e-08 32.6 0.0 1.8e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Colicin_im PF03857.8 OAJ14675.1 - 0.046 13.4 0.2 0.27 10.9 0.0 2.1 1 1 1 2 2 2 0 Colicin immunity protein Fungal_trans PF04082.13 OAJ14702.1 - 0.00059 18.7 0.0 0.0012 17.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Spt20 PF12090.3 OAJ14702.1 - 0.02 14.2 0.2 0.038 13.3 0.1 1.5 1 0 0 1 1 1 0 Spt20 family RAB3GAP2_N PF14655.1 OAJ14702.1 - 0.16 10.9 2.5 0.26 10.2 1.7 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Hid1 PF12722.2 OAJ14702.1 - 0.44 8.1 1.5 0.62 7.6 1.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Suf PF05843.9 OAJ14702.1 - 0.59 9.8 5.9 0.064 12.9 0.9 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Cpn60_TCP1 PF00118.19 OAJ14703.1 - 5.7e-134 447.3 7.3 6.7e-134 447.1 5.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Gp49 PF05973.9 OAJ14703.1 - 0.046 13.7 0.1 9.9 6.2 0.0 3.3 3 0 0 3 3 3 0 Phage derived protein Gp49-like (DUF891) DUF2422 PF10337.4 OAJ14704.1 - 0.015 14.0 2.4 0.018 13.8 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF4349 PF14257.1 OAJ14704.1 - 0.017 14.3 1.4 0.022 14.0 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) RRN3 PF05327.6 OAJ14704.1 - 0.061 11.4 3.0 0.069 11.2 2.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.7 OAJ14704.1 - 0.41 8.5 18.7 0.46 8.3 13.0 1.0 1 0 0 1 1 1 0 Nop14-like family AAA_11 PF13086.1 OAJ14704.1 - 0.44 10.0 3.1 0.56 9.7 2.2 1.1 1 0 0 1 1 1 0 AAA domain SLX9 PF15341.1 OAJ14705.1 - 1.5e-18 67.3 3.6 1.5e-18 67.3 2.5 1.6 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 Phage_int_SAM_1 PF02899.12 OAJ14725.1 - 0.066 13.3 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Myb_DNA-bind_3 PF12776.2 OAJ14747.1 - 3.4e-13 50.0 0.5 6.4e-13 49.1 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DEAD PF00270.24 OAJ14748.1 - 4.9e-39 133.5 0.0 7.7e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ14748.1 - 1e-23 82.9 0.0 2.7e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ14748.1 - 0.014 15.2 0.3 0.064 13.0 0.0 2.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DDE_Tnp_4 PF13359.1 OAJ14749.1 - 7.1e-09 35.4 0.1 1.3e-08 34.5 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ14749.1 - 1.4e-05 24.6 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein IRK PF01007.15 OAJ14749.1 - 0.015 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Inward rectifier potassium channel Pkinase PF00069.20 OAJ14772.1 - 5.4e-43 147.0 0.0 7.5e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ14772.1 - 1.1e-20 73.8 0.0 1.6e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ14772.1 - 3.6e-06 26.1 0.0 5.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ14772.1 - 0.00036 20.3 0.4 0.0044 16.7 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ14772.1 - 0.011 14.7 0.1 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 OAJ14772.1 - 0.044 13.1 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Dimer_Tnp_hAT PF05699.9 OAJ14774.1 - 2e-15 56.1 0.1 6.2e-15 54.5 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SHMT PF00464.14 OAJ14795.1 - 2.4e-167 556.3 0.0 2.8e-167 556.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 OAJ14795.1 - 0.0064 15.6 0.0 0.009 15.1 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 OAJ14795.1 - 0.019 13.9 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_5 PF00266.14 OAJ14795.1 - 0.08 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Cyt-b5 PF00173.23 OAJ14796.1 - 1.1e-20 73.1 0.0 2.3e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 OAJ14796.1 - 0.014 15.7 0.5 0.11 12.9 0.0 2.3 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily TspO_MBR PF03073.10 OAJ14797.1 - 2.7e-41 140.5 11.5 3.1e-41 140.3 8.0 1.0 1 0 0 1 1 1 1 TspO/MBR family DUF1771 PF08590.5 OAJ14797.1 - 0.072 13.1 1.9 0.13 12.2 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) PDH PF02153.12 OAJ14798.1 - 4.7e-12 45.3 0.0 6.6e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 OAJ14798.1 - 1.4e-07 31.8 0.0 4.5e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 OAJ14798.1 - 7.4e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 OAJ14798.1 - 0.00043 19.4 0.0 0.00075 18.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 OAJ14798.1 - 0.0012 18.9 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 OAJ14798.1 - 0.0059 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 ThiF family ApbA PF02558.11 OAJ14798.1 - 0.0092 15.4 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 OAJ14798.1 - 0.017 14.8 0.0 0.04 13.5 0.0 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pheromone PF08015.6 OAJ14819.1 - 0.03 15.1 0.8 0.03 15.1 0.5 4.7 4 1 0 4 4 4 0 Fungal mating-type pheromone Abhydrolase_6 PF12697.2 OAJ14840.1 - 2.1e-30 106.3 3.9 2.2e-30 106.2 0.2 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ14840.1 - 3.9e-18 65.8 0.0 2.3e-17 63.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ14840.1 - 7.7e-13 48.4 0.0 5e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 OAJ14840.1 - 5.3e-06 26.1 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_3 PF07859.8 OAJ14840.1 - 0.00033 20.3 0.4 0.0027 17.3 0.0 2.4 1 1 2 3 3 3 1 alpha/beta hydrolase fold Esterase PF00756.15 OAJ14840.1 - 0.0011 18.4 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.6 OAJ14840.1 - 0.0024 17.6 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 OAJ14840.1 - 0.0084 15.5 0.0 5.4 6.3 0.0 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Ndr PF03096.9 OAJ14840.1 - 0.029 12.8 0.0 0.05 12.0 0.0 1.3 1 0 0 1 1 1 0 Ndr family Hydrolase_4 PF12146.3 OAJ14840.1 - 0.085 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase DUF2305 PF10230.4 OAJ14840.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) zf-C3HC4_3 PF13920.1 OAJ14841.1 - 3.8e-06 26.4 7.7 3.8e-06 26.4 5.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 OAJ14841.1 - 9.4 6.8 24.1 0.14 12.5 0.4 5.6 6 0 0 6 6 6 0 Zinc finger, C2H2 type Pkinase PF00069.20 OAJ14864.1 - 5.2e-68 229.0 0.0 8.5e-68 228.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ14864.1 - 1.6e-29 102.7 0.0 2.6e-28 98.8 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 OAJ14864.1 - 0.00014 21.2 0.6 0.00025 20.4 0.4 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 OAJ14864.1 - 0.0002 20.3 0.7 0.52 9.2 0.0 3.1 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 OAJ14864.1 - 0.0019 17.9 3.7 0.29 10.8 0.1 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 OAJ14864.1 - 0.082 11.6 0.1 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Peptidase_S64 PF08192.6 OAJ14864.1 - 1.1 7.4 8.5 1.7 6.9 5.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 F-box-like PF12937.2 OAJ14887.1 - 3.6e-10 39.4 0.7 1e-09 37.9 0.5 1.9 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 OAJ14887.1 - 2e-07 30.6 0.9 0.0016 18.2 0.2 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box PF00646.28 OAJ14887.1 - 1.3e-06 27.9 0.7 3.5e-06 26.4 0.5 1.9 1 0 0 1 1 1 1 F-box domain MscS_porin PF12795.2 OAJ14888.1 - 0.011 15.0 0.4 0.011 15.0 0.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain ADIP PF11559.3 OAJ14888.1 - 0.027 14.3 0.5 0.028 14.3 0.3 1.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.4 OAJ14888.1 - 0.029 12.9 0.4 0.028 12.9 0.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3391 PF11871.3 OAJ14888.1 - 0.042 14.0 0.1 0.05 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Acyl-CoA_dh_2 PF08028.6 OAJ14888.1 - 0.11 12.7 0.7 0.12 12.6 0.5 1.1 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Sugarporin_N PF11471.3 OAJ14888.1 - 0.51 10.0 3.5 0.57 9.8 0.6 1.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension F-box PF00646.28 OAJ14889.1 - 1.5e-07 30.9 0.1 3.2e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ14889.1 - 0.015 15.0 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 F-box-like Ribosomal_L3 PF00297.17 OAJ14912.1 - 7.4e-31 107.5 1.9 3.7e-30 105.2 1.5 1.8 1 1 0 1 1 1 1 Ribosomal protein L3 Ribosomal_S15 PF00312.17 OAJ14913.1 - 2.5e-17 62.3 0.1 2.5e-17 62.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S15 EVE PF01878.13 OAJ14940.1 - 3.5e-27 95.1 0.0 6.2e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 EVE domain NAM-associated PF14303.1 OAJ14940.1 - 9.1 6.5 11.1 15 5.9 7.7 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain MCM PF00493.18 OAJ14941.1 - 9.4e-08 31.2 0.1 1.4e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family DMP1 PF07263.6 OAJ14941.1 - 0.0027 16.4 12.5 0.0041 15.9 8.7 1.3 1 0 0 1 1 1 1 Dentin matrix protein 1 (DMP1) DUF2457 PF10446.4 OAJ14941.1 - 3.9 6.0 8.2 1.1 7.8 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Thr_dehydrat_C PF00585.13 OAJ14942.1 - 1.4e-17 63.0 0.0 1.9e-13 49.8 0.0 3.2 3 0 0 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase Hid1 PF12722.2 OAJ14942.1 - 2.3e-07 28.9 0.0 2.4e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein SEN1_N PF12726.2 OAJ14968.1 - 3.7e-67 226.9 0.4 3.5e-66 223.7 0.2 2.3 1 1 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 OAJ14968.1 - 6.3e-67 225.6 2.7 6.3e-67 225.6 1.9 2.3 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 OAJ14968.1 - 7e-60 201.8 0.0 6.8e-59 198.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 OAJ14968.1 - 3.6e-10 39.4 0.0 1.6e-09 37.3 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 OAJ14968.1 - 2.2e-05 24.1 0.0 1.2 8.6 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 OAJ14968.1 - 4.2e-05 22.9 1.3 4.2e-05 22.9 0.9 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 OAJ14968.1 - 0.0011 18.4 0.4 0.3 10.4 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 OAJ14968.1 - 0.031 14.4 0.5 0.48 10.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 OAJ14968.1 - 0.06 13.1 3.6 1 9.1 2.5 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.24 OAJ14968.1 - 0.26 11.4 3.3 0.37 10.9 0.8 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TPR_12 PF13424.1 OAJ14994.1 - 4e-06 26.6 10.7 2.2 8.2 0.0 7.2 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ14994.1 - 0.0032 17.9 38.0 11 6.9 0.0 12.3 10 4 3 13 13 13 2 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ14994.1 - 0.012 15.7 12.0 1.2e+02 3.2 0.0 8.2 8 0 0 8 8 8 0 Tetratricopeptide repeat PPR_3 PF13812.1 OAJ14994.1 - 0.022 15.0 0.0 1.3 9.4 0.0 4.2 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Mad3_BUB1_I PF08311.7 OAJ14994.1 - 0.039 13.7 3.5 0.25 11.1 0.2 3.9 4 1 0 4 4 4 0 Mad3/BUB1 homology region 1 HAT PF02184.11 OAJ14994.1 - 0.41 10.4 8.1 2.4 7.9 0.1 5.7 5 0 0 5 5 5 0 HAT (Half-A-TPR) repeat TPR_2 PF07719.12 OAJ14994.1 - 1.1 9.3 19.8 4.8 7.3 0.1 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Methyltransf_23 PF13489.1 OAJ14995.1 - 7.1e-22 77.8 0.0 2.2e-21 76.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ14995.1 - 1.7e-15 57.2 0.0 9.7e-15 54.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ14995.1 - 1.3e-13 50.7 0.0 1.6e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ14995.1 - 3.8e-13 49.7 0.1 2e-12 47.4 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ14995.1 - 5.6e-12 46.2 0.1 1.1e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ14995.1 - 2.5e-07 30.7 1.8 4.7e-07 29.8 0.5 2.1 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 OAJ14995.1 - 9.8e-07 28.1 0.0 0.011 14.8 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 OAJ14995.1 - 6.9e-06 24.9 0.0 0.0044 15.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 OAJ14995.1 - 8.2e-05 22.9 0.0 0.00017 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 OAJ14995.1 - 0.00019 20.6 0.0 0.0004 19.6 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 OAJ14995.1 - 0.0037 16.9 0.0 0.0071 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ14995.1 - 0.006 15.9 0.1 0.021 14.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain NodS PF05401.6 OAJ14995.1 - 0.0088 15.4 0.0 3.5 6.9 0.0 2.2 2 0 0 2 2 2 2 Nodulation protein S (NodS) DREV PF05219.7 OAJ14995.1 - 0.019 13.8 0.0 0.046 12.5 0.0 1.6 1 1 0 1 1 1 0 DREV methyltransferase Ubie_methyltran PF01209.13 OAJ14995.1 - 0.043 12.9 0.0 0.17 10.9 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family TPMT PF05724.6 OAJ14995.1 - 0.081 12.3 0.0 0.28 10.5 0.0 1.7 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MetW PF07021.7 OAJ14995.1 - 0.087 12.1 0.0 0.45 9.8 0.0 2.0 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW DPBB_1 PF03330.13 OAJ15018.1 - 3.2e-05 23.8 0.0 7.2e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ15018.1 - 0.0025 17.4 0.2 0.0046 16.6 0.1 1.3 1 1 0 1 1 1 1 Barwin family Cyclin_N PF00134.18 OAJ15019.1 - 2.3e-11 43.3 0.0 4.1e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 OAJ15019.1 - 0.023 14.4 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DUF1018 PF06252.7 OAJ15021.1 - 0.074 13.5 0.0 0.087 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) HsbA PF12296.3 OAJ15050.1 - 1.5e-12 47.4 6.8 1.5e-12 47.4 4.7 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DivIVA PF05103.8 OAJ15050.1 - 0.027 14.4 0.4 0.08 12.9 0.0 1.8 2 0 0 2 2 2 0 DivIVA protein NMO PF03060.10 OAJ15070.1 - 5e-51 173.8 0.6 4e-50 170.8 0.4 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 OAJ15070.1 - 5.2e-07 28.8 0.9 0.0079 15.1 0.5 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 OAJ15070.1 - 0.00014 20.8 0.1 0.00023 20.1 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 OAJ15070.1 - 0.026 13.8 0.1 0.053 12.7 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Glu_synthase PF01645.12 OAJ15070.1 - 0.045 12.6 1.3 0.14 11.0 0.9 1.9 1 1 0 1 1 1 0 Conserved region in glutamate synthase DUF1902 PF08972.6 OAJ15070.1 - 0.06 12.9 1.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) DHO_dh PF01180.16 OAJ15070.1 - 0.12 11.3 0.2 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase UBN2_2 PF14227.1 OAJ15071.1 - 3.8e-12 45.8 0.0 6.9e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ15071.1 - 0.00016 21.4 0.1 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ15071.1 - 0.00027 20.7 4.9 0.00027 20.7 3.4 2.1 2 0 0 2 2 2 1 Zinc knuckle DUF4219 PF13961.1 OAJ15071.1 - 0.0009 18.6 0.1 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) zf-CCHC_2 PF13696.1 OAJ15071.1 - 0.0081 15.6 3.0 0.018 14.4 2.0 1.6 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.3 OAJ15071.1 - 0.19 11.6 5.0 0.83 9.5 0.9 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G NifU_N PF01592.11 OAJ15072.1 - 1.8e-52 176.6 0.1 2.9e-52 175.9 0.1 1.4 1 0 0 1 1 1 1 NifU-like N terminal domain RVT_1 PF00078.22 OAJ15097.1 - 4.9e-19 68.5 0.0 1.2e-18 67.2 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) INCENP_ARK-bind PF03941.10 OAJ15123.1 - 1.5e-07 31.1 0.2 4e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region DNA_primase_S PF01896.14 OAJ15124.1 - 1.2e-52 177.5 0.0 2e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit HTH_36 PF13730.1 OAJ15124.1 - 0.034 14.2 0.1 0.37 10.9 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2890 PF11081.3 OAJ15125.1 - 0.097 12.7 0.1 0.097 12.7 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2890) Seipin PF06775.9 OAJ15152.1 - 2.7e-39 134.7 0.0 9e-26 90.6 0.0 2.2 2 0 0 2 2 2 2 Putative adipose-regulatory protein (Seipin) SDA1 PF05285.7 OAJ15152.1 - 2.7 7.1 31.1 1.4 8.1 9.4 2.4 2 0 0 2 2 2 0 SDA1 tRNA-synt_His PF13393.1 OAJ15153.1 - 2.8e-37 128.4 1.1 8.6e-33 113.7 0.0 3.0 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 OAJ15153.1 - 1.3e-18 67.1 0.0 2.2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ15153.1 - 2e-07 30.8 0.0 3.8e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.15 OAJ15153.1 - 2.4e-06 27.1 2.0 2.4e-06 27.1 1.4 2.2 2 0 0 2 2 2 1 WHEP-TRS domain tRNA-synt_2 PF00152.15 OAJ15153.1 - 9e-05 21.3 0.2 0.013 14.3 0.1 2.4 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) RNA_pol_A_bac PF01000.21 OAJ15180.1 - 3e-27 94.9 0.0 4.7e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 OAJ15180.1 - 1e-15 56.5 0.0 1.4e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.20 OAJ15181.1 - 1.4e-62 211.2 0.0 1.3e-61 208.0 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ15181.1 - 5.6e-34 117.3 0.0 4.2e-27 94.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ15181.1 - 1.6e-06 27.3 0.1 0.0012 17.8 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Seadorna_VP7 PF07387.6 OAJ15181.1 - 0.0009 18.1 0.0 0.0017 17.2 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 OAJ15181.1 - 0.0021 17.8 0.8 0.02 14.6 0.0 2.9 4 0 0 4 4 4 1 Phosphotransferase enzyme family Palm_thioest PF02089.10 OAJ15182.1 - 2.9e-64 216.7 0.0 3.4e-51 173.8 0.0 2.0 2 0 0 2 2 2 2 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 OAJ15182.1 - 4.8e-05 23.3 0.1 9.9e-05 22.3 0.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ15182.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold COQ7 PF03232.8 OAJ15206.1 - 2.5e-55 186.6 0.0 4.2e-55 185.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 SYF2 PF08231.7 OAJ15207.1 - 2e-41 141.6 5.5 2e-41 141.6 3.8 1.9 2 0 0 2 2 2 1 SYF2 splicing factor WD40 PF00400.27 OAJ15207.1 - 0.02 14.7 0.0 1.4 8.9 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat BBE PF08031.7 OAJ15235.1 - 0.043 13.7 0.0 9.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Berberine and berberine like DUF608 PF04685.8 OAJ15235.1 - 0.054 12.2 0.3 0.06 12.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF608 Cation_efflux PF01545.16 OAJ15236.1 - 2.7e-57 194.0 6.2 2.7e-57 194.0 4.3 3.6 4 0 0 4 4 4 1 Cation efflux family DUF1713 PF08213.6 OAJ15237.1 - 4.5e-10 38.9 24.2 7.8e-10 38.1 16.8 1.4 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) TSA PF03249.8 OAJ15237.1 - 0.13 10.7 8.1 0.16 10.4 5.6 1.1 1 0 0 1 1 1 0 Type specific antigen DDHD PF02862.12 OAJ15237.1 - 0.33 10.6 6.8 0.41 10.4 4.7 1.1 1 0 0 1 1 1 0 DDHD domain SOBP PF15279.1 OAJ15237.1 - 1.1 9.6 10.8 1.2 9.4 7.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Protamine_P2 PF00841.14 OAJ15237.1 - 8.4 7.0 14.7 19 5.8 10.2 1.6 1 1 0 1 1 1 0 Sperm histone P2 ABC_tran_2 PF12848.2 OAJ15237.1 - 8.5 6.2 13.3 13 5.6 9.2 1.3 1 0 0 1 1 1 0 ABC transporter Pkinase PF00069.20 OAJ15257.1 - 5.3e-50 169.9 0.0 7.7e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ15257.1 - 1.8e-29 102.5 0.0 3.6e-29 101.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase AAA_27 PF13514.1 OAJ15257.1 - 0.0045 14.7 6.8 0.0064 14.2 4.7 1.1 1 0 0 1 1 1 1 AAA domain Kdo PF06293.9 OAJ15257.1 - 0.021 13.8 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IncA PF04156.9 OAJ15257.1 - 0.033 13.7 0.9 0.058 12.9 0.6 1.3 1 0 0 1 1 1 0 IncA protein Kinase-like PF14531.1 OAJ15257.1 - 0.088 11.7 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like GAS PF13851.1 OAJ15257.1 - 0.094 11.9 1.3 0.16 11.1 0.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Allexi_40kDa PF05549.6 OAJ15257.1 - 0.16 11.2 1.2 0.56 9.4 0.3 2.1 1 1 0 2 2 2 0 Allexivirus 40kDa protein CENP-F_leu_zip PF10473.4 OAJ15257.1 - 0.41 10.5 3.9 0.58 10.0 1.7 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4140 PF13600.1 OAJ15257.1 - 0.47 10.9 3.7 5 7.6 1.7 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Uds1 PF15456.1 OAJ15257.1 - 0.87 9.5 3.9 2 8.4 2.7 1.5 1 1 0 1 1 1 0 Up-regulated During Septation DivIC PF04977.10 OAJ15257.1 - 2.1 7.8 6.4 3.1 7.3 0.2 2.7 2 1 1 3 3 3 0 Septum formation initiator Dimer_Tnp_hAT PF05699.9 OAJ15258.1 - 4e-16 58.4 0.0 9e-16 57.2 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DBD_Tnp_Hermes PF10683.4 OAJ15258.1 - 0.0021 17.4 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 Hermes transposase DNA-binding domain DUF4413 PF14372.1 OAJ15258.1 - 0.24 11.3 0.0 0.51 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Senescence_reg PF04520.8 OAJ15309.1 - 0.18 12.3 1.6 0.3 11.5 0.2 1.9 2 0 0 2 2 2 0 Senescence regulator DUF3245 PF11595.3 OAJ15309.1 - 2.1 8.6 3.9 3.5 7.9 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) PI-PLC-X PF00388.14 OAJ15310.1 - 4.7e-49 165.5 0.0 8.3e-49 164.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 OAJ15310.1 - 2.4e-37 127.4 0.0 5e-37 126.4 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 OAJ15310.1 - 1.2e-07 31.5 0.2 2.9e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.12 OAJ15310.1 - 0.072 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Phosphoprotein PF00922.12 OAJ15310.1 - 1.7 7.7 5.6 3.1 6.9 2.3 2.2 2 0 0 2 2 2 0 Vesiculovirus phosphoprotein S4 PF01479.20 OAJ15329.1 - 3e-13 48.9 0.1 5.1e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 OAJ15329.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 S4 domain SAPS PF04499.10 OAJ15329.1 - 0.06 11.9 0.2 0.076 11.6 0.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Secretin_N_2 PF07655.8 OAJ15329.1 - 0.42 11.0 0.1 0.42 11.0 0.1 3.5 3 1 0 3 3 3 0 Secretin N-terminal domain Ras PF00071.17 OAJ15330.1 - 8.7e-45 152.0 0.0 4.2e-42 143.2 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 OAJ15330.1 - 2e-20 73.4 0.0 3.2e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ15330.1 - 1.4e-11 43.9 0.0 2.3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ15330.1 - 3.1e-05 23.2 0.0 4.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 OAJ15330.1 - 0.033 14.1 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 OAJ15330.1 - 0.073 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RVT_1 PF00078.22 OAJ15350.1 - 5.3e-18 65.1 0.0 9.1e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.27 OAJ15378.1 - 6.3e-17 60.7 12.2 4.7e-09 35.7 0.8 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 OAJ15378.1 - 1.9e-06 27.7 0.0 0.018 14.7 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 OAJ15378.1 - 5.9e-05 22.6 0.1 0.013 14.9 0.0 2.9 3 0 0 3 3 3 1 PQQ-like domain PQQ_3 PF13570.1 OAJ15378.1 - 0.0012 19.0 0.0 0.14 12.4 0.0 2.9 2 0 0 2 2 2 1 PQQ-like domain Mito_fiss_reg PF05308.6 OAJ15378.1 - 0.0044 16.4 2.8 0.0044 16.4 1.9 1.6 2 0 0 2 2 2 1 Mitochondrial fission regulator Kelch_4 PF13418.1 OAJ15378.1 - 0.022 14.4 0.1 2.5 7.9 0.0 2.9 2 0 0 2 2 2 0 Galactose oxidase, central domain LigD_N PF13298.1 OAJ15378.1 - 0.092 12.8 0.1 1.9 8.6 0.0 2.7 2 1 1 3 3 3 0 DNA polymerase Ligase (LigD) Cytochrom_D1 PF02239.11 OAJ15378.1 - 0.12 10.6 0.0 5.4 5.2 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain bZIP_1 PF00170.16 OAJ15379.1 - 9.9e-11 41.4 3.2 1.7e-10 40.7 2.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor Aft1_HRA PF11786.3 OAJ15379.1 - 3.3e-09 36.8 22.3 3.3e-09 36.8 15.4 5.0 3 1 0 3 3 3 1 Aft1 HRA domain bZIP_2 PF07716.10 OAJ15379.1 - 4.6e-07 29.5 5.7 1e-06 28.4 3.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Nop53 PF07767.6 OAJ15379.1 - 0.017 14.0 3.1 0.036 13.0 2.2 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.9 OAJ15379.1 - 0.35 8.8 3.8 0.71 7.8 2.6 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF3597 PF12200.3 OAJ15407.1 - 1.6 9.1 9.3 8.8 6.7 1.7 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3597) Peptidase_M57 PF12388.3 OAJ15407.1 - 7 5.9 8.2 0.21 10.9 1.0 1.9 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase LIM PF00412.17 OAJ15408.1 - 1.4e-14 53.8 14.7 0.00021 21.2 0.0 5.5 6 0 0 6 6 6 4 LIM domain TPR_12 PF13424.1 OAJ15410.1 - 5.9e-35 119.0 65.1 8.8e-08 31.9 2.5 6.4 3 1 5 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ15410.1 - 3.5e-34 115.7 36.2 1.9e-05 24.4 0.1 8.6 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ15410.1 - 3e-13 48.5 28.0 0.093 12.6 0.2 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ15410.1 - 2.9e-11 42.8 25.8 0.002 17.7 0.3 6.2 4 2 2 6 6 6 4 TPR repeat TPR_1 PF00515.23 OAJ15410.1 - 1.4e-07 30.8 15.7 0.28 10.8 0.1 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ15410.1 - 1.1e-05 24.8 19.1 14 5.7 0.0 8.2 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF3366 PF11846.3 OAJ15410.1 - 0.00023 21.0 2.8 0.76 9.6 0.0 3.4 1 1 1 3 3 3 2 Domain of unknown function (DUF3366) Vps4_C PF09336.5 OAJ15410.1 - 0.00024 20.8 0.0 4.3 7.2 0.0 4.3 4 0 0 4 4 4 1 Vps4 C terminal oligomerisation domain DUF3856 PF12968.2 OAJ15410.1 - 0.00043 20.1 20.0 0.72 9.6 3.0 4.9 1 1 4 5 5 5 3 Domain of Unknown Function (DUF3856) TPR_16 PF13432.1 OAJ15410.1 - 0.0047 17.5 32.3 0.098 13.3 0.2 6.8 4 3 3 7 7 7 2 Tetratricopeptide repeat Ssu72 PF04722.8 OAJ15410.1 - 0.0073 15.6 0.7 76 2.5 0.0 5.0 1 1 4 6 6 6 0 Ssu72-like protein TPR_14 PF13428.1 OAJ15410.1 - 0.018 15.6 31.5 4.9 8.0 0.0 8.1 8 1 1 9 9 7 0 Tetratricopeptide repeat PLD_C PF12357.3 OAJ15410.1 - 0.096 12.2 0.0 27 4.3 0.0 3.2 3 0 0 3 3 3 0 Phospholipase D C terminal TPR_7 PF13176.1 OAJ15410.1 - 0.1 12.4 27.1 4.5 7.3 0.1 8.2 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ15410.1 - 0.28 11.4 5.1 52 4.3 0.0 5.8 8 0 0 8 8 7 0 Tetratricopeptide repeat Apc5 PF12862.2 OAJ15410.1 - 0.37 10.6 22.1 4.5 7.1 0.0 7.3 3 1 2 8 8 8 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.1 OAJ15410.1 - 0.46 11.0 14.0 45 4.8 0.0 8.1 10 0 0 10 10 9 0 Tetratricopeptide repeat SPOR PF05036.8 OAJ15410.1 - 1.2 9.3 3.9 15 5.8 0.3 3.4 2 1 1 3 3 3 0 Sporulation related domain INTS5_N PF14837.1 OAJ15410.1 - 1.8 7.9 8.3 5.9 6.2 0.3 4.5 1 1 1 4 4 4 0 Integrator complex subunit 5 N-terminus Tcp11 PF05794.8 OAJ15436.1 - 8.7e-61 205.9 0.2 5.6e-45 153.8 0.7 5.0 4 1 0 4 4 4 4 T-complex protein 11 Motile_Sperm PF00635.21 OAJ15437.1 - 3.1e-20 71.8 0.1 6.7e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Pex14_N PF04695.8 OAJ15437.1 - 0.99 9.4 7.7 1.4 8.9 0.8 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region rve PF00665.21 OAJ15461.1 - 3.1e-16 59.5 0.0 6.6e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ15462.1 - 1.4e-18 67.0 0.0 2.5e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ15462.1 - 2.5e-06 27.8 0.0 6.5e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ15462.1 - 0.00025 20.7 0.1 0.00093 18.9 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TMF_DNA_bd PF12329.3 OAJ15462.1 - 0.41 10.4 0.0 0.85 9.4 0.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding rve PF00665.21 OAJ15463.1 - 1e-05 25.6 0.0 2.1e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain MULE PF10551.4 OAJ15486.1 - 1.2e-19 70.2 0.2 3.3e-19 68.8 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ15486.1 - 1.8e-08 33.3 2.1 1.9e-08 33.2 0.1 1.9 2 0 0 2 2 2 1 Transposase, Mutator family DDE_Tnp_IS240 PF13610.1 OAJ15486.1 - 5.3e-05 23.1 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 DDE domain DDE_Tnp_ISL3 PF01610.12 OAJ15486.1 - 0.00012 21.7 0.3 0.00071 19.2 0.0 2.0 1 1 1 2 2 2 1 Transposase rve PF00665.21 OAJ15486.1 - 0.016 15.3 0.1 0.041 13.9 0.1 1.7 1 0 0 1 1 1 0 Integrase core domain DUF1722 PF08349.6 OAJ15486.1 - 0.16 11.8 0.0 0.57 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Retrotrans_gag PF03732.12 OAJ15512.1 - 6.7e-17 61.3 1.0 1.2e-16 60.5 0.7 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAJ15512.1 - 0.00025 20.8 0.6 0.00043 20.0 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ15512.1 - 0.02 14.5 0.5 0.042 13.5 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Roughex PF06020.6 OAJ15512.1 - 0.05 12.2 0.7 0.084 11.5 0.5 1.3 1 0 0 1 1 1 0 Drosophila roughex protein CPSase_L_D2 PF02786.12 OAJ15513.1 - 3e-50 170.4 0.0 4.8e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Carboxyl_trans PF01039.17 OAJ15513.1 - 1.4e-45 155.6 0.1 3e-41 141.3 0.0 2.1 2 0 0 2 2 2 2 Carboxyl transferase domain Biotin_carb_C PF02785.14 OAJ15513.1 - 3e-21 75.4 0.0 6.8e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 OAJ15513.1 - 5.4e-20 71.5 0.0 3.9e-18 65.5 0.0 2.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_lipoyl PF00364.17 OAJ15513.1 - 1.5e-17 62.9 0.1 3.2e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 OAJ15513.1 - 6.3e-11 42.3 0.0 1.5e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 OAJ15513.1 - 8.9e-11 41.2 0.3 0.00037 20.0 0.0 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like ATPgrasp_Ter PF15632.1 OAJ15513.1 - 6.1e-07 28.4 0.0 6.5e-06 25.1 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon HlyD_2 PF12700.2 OAJ15513.1 - 2.3e-05 23.7 0.8 0.021 13.9 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 OAJ15513.1 - 5e-05 22.7 5.4 0.0016 17.8 1.9 2.3 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 OAJ15513.1 - 0.0031 17.8 0.2 2.2 8.6 0.0 2.8 3 0 0 3 3 2 1 HlyD family secretion protein RnfC_N PF13375.1 OAJ15513.1 - 0.0045 16.6 0.1 0.016 14.9 0.1 1.9 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain MdcE PF06833.6 OAJ15513.1 - 0.0054 15.9 0.0 0.0091 15.2 0.0 1.4 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) DUF2118 PF09891.4 OAJ15513.1 - 0.011 15.4 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) ATPgrasp_ST PF14397.1 OAJ15513.1 - 0.03 13.4 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp RVT_1 PF00078.22 OAJ15514.1 - 6.8e-23 81.1 0.0 1.1e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 OAJ15514.1 - 3.2e-07 30.3 0.0 5.8e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAJ15514.1 - 2.4e-05 24.7 0.0 4.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ15514.1 - 0.0002 21.1 0.0 0.00043 20.0 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease TFIIA PF03153.8 OAJ15537.1 - 0.0013 18.7 23.7 0.0013 18.7 16.4 3.6 2 2 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 OAJ15537.1 - 1.9 6.3 16.2 3.5 5.4 11.2 1.3 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 OAJ15537.1 - 7.6 6.0 10.9 9.3 5.8 5.8 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region TPR_2 PF07719.12 OAJ15538.1 - 0.016 15.0 2.1 1.3 9.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 OAJ15538.1 - 0.043 14.1 2.9 7.9 6.7 0.9 2.5 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_12 PF13424.1 OAJ15538.1 - 0.076 12.9 7.1 6.4 6.8 1.8 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat p450 PF00067.17 OAJ15560.1 - 1.9e-10 39.8 0.0 2.7e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 AAA PF00004.24 OAJ15562.1 - 3.8e-14 53.0 0.0 8.2e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 OAJ15562.1 - 1.3e-12 47.7 0.0 6.8e-12 45.3 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 OAJ15562.1 - 5.4e-08 33.0 0.0 1.7e-07 31.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain Rep_fac_C PF08542.6 OAJ15562.1 - 3.5e-06 26.9 0.0 8.1e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_19 PF13245.1 OAJ15562.1 - 9e-06 25.3 0.0 6.4e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Rad17 PF03215.10 OAJ15562.1 - 9.3e-06 24.5 0.0 0.00088 18.0 0.0 2.2 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 OAJ15562.1 - 0.00027 20.9 0.9 0.015 15.2 0.0 3.2 2 1 0 3 3 3 1 AAA ATPase domain DUF2075 PF09848.4 OAJ15562.1 - 0.00033 19.7 0.0 0.00051 19.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 OAJ15562.1 - 0.00059 19.8 0.1 0.019 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 OAJ15562.1 - 0.00074 18.6 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 OAJ15562.1 - 0.0018 17.8 0.0 0.0068 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 OAJ15562.1 - 0.0019 17.6 0.0 0.0052 16.2 0.0 1.7 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.1 OAJ15562.1 - 0.0032 17.0 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 OAJ15562.1 - 0.013 14.7 0.0 0.081 12.0 0.0 2.1 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 OAJ15562.1 - 0.023 14.2 0.2 0.051 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAJ15562.1 - 0.028 13.8 0.2 0.13 11.6 0.2 2.3 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 OAJ15562.1 - 0.046 13.1 0.1 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.8 OAJ15562.1 - 0.086 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 OAJ15562.1 - 0.088 12.2 0.1 0.78 9.1 0.0 2.1 1 1 1 2 2 2 0 AAA-like domain AAA_5 PF07728.9 OAJ15562.1 - 0.09 12.4 0.3 0.94 9.1 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 OAJ15562.1 - 0.14 10.7 0.0 0.27 9.7 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SseC PF04888.7 OAJ15584.1 - 0.0045 16.3 58.4 0.0083 15.4 40.5 1.4 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Unstab_antitox PF09720.5 OAJ15584.1 - 0.01 15.4 2.1 0.016 14.8 0.3 2.2 2 0 0 2 2 2 0 Putative addiction module component DUF4218 PF13960.1 OAJ15585.1 - 7.4e-06 25.4 0.2 1.5e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Ribosomal_L18e PF00828.14 OAJ15616.1 - 4.3e-24 85.3 0.9 5.4e-24 85.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 UAA PF08449.6 OAJ15617.1 - 4.5e-66 222.8 4.4 6.4e-59 199.3 3.5 2.4 2 1 0 2 2 2 2 UAA transporter family EamA PF00892.15 OAJ15617.1 - 5.1e-06 26.5 2.4 5.1e-06 26.5 1.6 4.5 5 0 0 5 5 5 1 EamA-like transporter family TPT PF03151.11 OAJ15617.1 - 1.9e-05 24.3 10.6 0.0022 17.6 5.2 3.0 2 1 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 OAJ15617.1 - 0.0018 17.4 4.9 0.069 12.2 0.1 2.6 3 0 0 3 3 3 2 Nucleotide-sugar transporter UPF0546 PF10639.4 OAJ15617.1 - 0.017 14.9 2.7 1.4 8.7 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 EmrE PF13536.1 OAJ15617.1 - 0.019 15.1 5.3 0.019 15.1 3.6 3.4 3 1 0 3 3 3 0 Multidrug resistance efflux transporter CbiG_N PF11760.3 OAJ15617.1 - 0.11 12.2 2.1 0.19 11.4 0.1 2.2 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal RRM_1 PF00076.17 OAJ15618.1 - 1.4e-14 53.4 0.0 2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ15618.1 - 5.2e-11 42.3 0.0 8e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ15618.1 - 1.1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF566 PF04484.7 OAJ15618.1 - 6.3 6.2 10.3 9.3 5.6 7.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) SUR7 PF06687.7 OAJ15619.1 - 5.7e-17 61.9 7.3 7.9e-17 61.5 5.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 OAJ15619.1 - 2.6e-08 33.7 2.2 2.6e-08 33.7 1.5 2.2 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF3754 PF12576.3 OAJ15619.1 - 1.2 8.8 4.7 2.3 7.8 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) GFA PF04828.9 OAJ15647.1 - 0.039 13.8 0.1 0.059 13.3 0.1 1.3 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme EMA PF02488.10 OAJ15647.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Merozoite Antigen Bac_luciferase PF00296.15 OAJ15648.1 - 0.26 10.3 2.7 0.31 10.1 1.8 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase DUF883 PF05957.8 OAJ15648.1 - 3.1 8.2 10.0 7.8 6.9 2.7 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3432 PF11914.3 OAJ15673.1 - 0.32 11.0 7.6 0.5 10.4 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Glyco_transf_20 PF00982.16 OAJ15674.1 - 2.3e-142 474.8 0.0 3.2e-142 474.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 OAJ15674.1 - 4.5e-22 78.1 0.0 8.2e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Methyltransf_28 PF02636.12 OAJ15704.1 - 7.5e-33 113.9 0.0 1.4e-32 113.1 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rsm22 PF09243.5 OAJ15704.1 - 4.1e-26 91.6 9.6 1.1e-09 37.7 0.0 5.9 4 2 1 5 5 5 3 Mitochondrial small ribosomal subunit Rsm22 RrnaAD PF00398.15 OAJ15704.1 - 0.0035 16.4 0.0 0.006 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 OAJ15704.1 - 0.055 13.9 0.0 0.33 11.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ15704.1 - 0.072 13.1 1.4 0.43 10.6 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain GPI-anchored PF10342.4 OAJ15705.1 - 8.4e-13 48.6 1.9 8.4e-13 48.6 1.3 2.4 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.4 OAJ15705.1 - 0.2 10.3 8.0 0.21 10.2 5.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1206 PF06724.6 OAJ15705.1 - 0.25 11.1 5.5 0.37 10.5 0.2 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) Pex14_N PF04695.8 OAJ15705.1 - 1.9 8.5 11.0 1.1 9.3 5.8 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DNA_pol_viral_N PF00242.12 OAJ15705.1 - 4.5 6.1 11.1 6.1 5.7 7.7 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SSP160 PF06933.6 OAJ15705.1 - 7.7 4.3 29.0 16 3.3 20.1 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Macoilin PF09726.4 OAJ15705.1 - 9.5 4.3 13.6 12 4.0 9.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Cyclin_N PF00134.18 OAJ15732.1 - 1.4e-40 137.8 0.7 2.7e-40 136.8 0.2 1.8 2 1 1 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ15732.1 - 2.5e-28 98.3 0.0 7.3e-28 96.8 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Peptidase_M28 PF04389.12 OAJ15733.1 - 6.4e-27 94.4 0.0 1.5e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 OAJ15733.1 - 0.037 13.5 0.1 0.091 12.2 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 DPM2 PF07297.7 OAJ15734.1 - 3.7e-24 84.7 0.2 4.5e-24 84.5 0.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 OAJ15734.1 - 8.5e-06 25.4 0.1 9.7e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 PIG-P Sensor PF13796.1 OAJ15734.1 - 0.017 14.7 1.6 0.018 14.6 1.1 1.1 1 0 0 1 1 1 0 Putative sensor DUF1206 PF06724.6 OAJ15734.1 - 0.25 11.1 3.9 0.99 9.2 0.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) DUF1469 PF07332.6 OAJ15734.1 - 0.74 9.5 4.1 3.4 7.4 2.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) DJ-1_PfpI PF01965.19 OAJ15735.1 - 1.8e-26 92.3 0.1 2.8e-26 91.7 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 OAJ15735.1 - 2.6e-12 46.3 0.0 3.4e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase VWA_2 PF13519.1 OAJ15735.1 - 0.027 14.5 0.0 0.11 12.5 0.0 1.9 1 1 1 2 2 2 0 von Willebrand factor type A domain DUF1793 PF08760.6 OAJ15761.1 - 1e-66 224.0 0.5 2e-66 223.0 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF3653 PF12375.3 OAJ15762.1 - 1.3 9.2 5.2 1.3 9.3 1.3 2.5 1 1 2 3 3 3 0 Phage protein Proteasome PF00227.21 OAJ15763.1 - 2e-50 170.7 0.2 2.7e-50 170.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit DUF2188 PF09954.4 OAJ15763.1 - 0.0022 17.8 0.5 0.072 13.0 0.1 2.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2188) PfkB PF00294.19 OAJ15764.1 - 3.3e-09 36.3 0.5 5.4e-07 29.0 0.0 2.6 3 0 0 3 3 3 2 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 OAJ15764.1 - 4.4e-09 35.8 0.0 9.6e-09 34.7 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DPPIV_N PF00930.16 OAJ15789.1 - 3.2e-72 243.0 0.0 9.5e-71 238.2 0.0 2.3 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 OAJ15789.1 - 2.1e-41 141.5 0.5 3.4e-41 140.8 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAJ15789.1 - 1.5e-05 24.7 0.3 4.8e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 OAJ15789.1 - 0.00014 21.4 0.6 0.00047 19.6 0.3 1.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 OAJ15789.1 - 0.031 12.7 0.0 0.084 11.3 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Actin PF00022.14 OAJ15816.1 - 2.1e-99 332.5 0.0 3.8e-99 331.7 0.0 1.4 1 1 0 1 1 1 1 Actin Sad1_UNC PF07738.8 OAJ15817.1 - 1.3e-11 44.4 0.0 0.00019 21.2 0.0 3.1 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal SNARE PF05739.14 OAJ15817.1 - 0.093 12.4 1.3 0.23 11.1 0.9 1.7 1 0 0 1 1 1 0 SNARE domain Ebola_NP PF05505.7 OAJ15817.1 - 7 4.5 6.8 12 3.8 4.7 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein BOP1NT PF08145.7 OAJ15818.1 - 9.1e-103 343.5 1.5 1.4e-102 342.9 1.1 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 OAJ15818.1 - 1.2e-26 91.5 1.2 4.2e-05 23.2 0.0 7.3 8 0 0 8 8 8 4 WD domain, G-beta repeat Daxx PF03344.10 OAJ15818.1 - 2.2 6.6 23.1 3.5 6.0 16.0 1.2 1 0 0 1 1 1 0 Daxx Family Pox_RNA_Pol_19 PF05320.7 OAJ15818.1 - 3.9 7.2 13.6 7.5 6.2 9.4 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Nop14 PF04147.7 OAJ15818.1 - 5 4.9 32.3 7.1 4.4 22.4 1.1 1 0 0 1 1 1 0 Nop14-like family OTCace_N PF02729.16 OAJ15846.1 - 2.2e-43 147.3 0.1 3.2e-43 146.8 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 OAJ15846.1 - 1e-41 142.4 0.0 1.6e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Pribosyltran_N PF13793.1 OAJ15848.1 - 2.1e-44 149.9 0.0 9.6e-43 144.6 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 OAJ15848.1 - 9.9e-35 119.9 3.0 2.8e-31 108.6 0.4 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 OAJ15848.1 - 2.7e-14 52.9 0.3 5.2e-13 48.8 0.3 2.7 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 OAJ15848.1 - 0.011 14.9 0.1 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Rft-1 PF04506.8 OAJ15849.1 - 4.9e-64 216.6 0.7 1.1e-62 212.2 0.2 2.7 2 1 0 2 2 2 1 Rft protein RabGAP-TBC PF00566.13 OAJ15850.1 - 1.1e-36 126.3 0.1 1.5e-36 125.9 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ADSL_C PF10397.4 OAJ15850.1 - 0.0063 16.4 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Zn_clus PF00172.13 OAJ15877.1 - 0.00011 22.0 10.3 0.00019 21.2 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 3HCDH_N PF02737.13 OAJ15904.1 - 5.8e-56 188.9 1.4 1.1e-55 188.0 1.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 OAJ15904.1 - 2.2e-34 117.7 0.0 5e-34 116.5 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 OAJ15904.1 - 2.6e-05 23.9 0.6 4.7e-05 23.1 0.4 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF1188 PF06690.6 OAJ15904.1 - 0.0031 16.6 0.4 0.016 14.3 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1188) Saccharop_dh PF03435.13 OAJ15904.1 - 0.0058 15.6 0.2 0.0083 15.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 OAJ15904.1 - 0.0094 15.3 1.2 0.078 12.3 0.7 2.5 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 OAJ15904.1 - 0.047 13.5 3.1 0.23 11.3 1.7 2.3 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 OAJ15904.1 - 0.065 13.4 1.8 0.49 10.6 0.3 2.5 3 0 0 3 3 3 0 Putative NAD(P)-binding DapB_N PF01113.15 OAJ15904.1 - 0.079 12.8 2.4 0.29 11.0 0.8 2.5 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Rrf2 PF02082.15 OAJ15904.1 - 0.11 12.6 0.0 34 4.6 0.0 3.1 3 0 0 3 3 3 0 Transcriptional regulator His_Phos_1 PF00300.17 OAJ15905.1 - 1.3e-40 139.0 0.0 1.5e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3414 PF11894.3 OAJ15928.1 - 6e-247 822.4 11.2 7.1e-247 822.1 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Myc_N PF01056.13 OAJ15951.1 - 0.0016 17.7 0.4 0.0017 17.5 0.3 1.1 1 0 0 1 1 1 1 Myc amino-terminal region PBP1_TM PF14812.1 OAJ15951.1 - 0.0028 17.9 1.1 0.0043 17.3 0.8 1.3 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal TIMELESS_C PF05029.8 OAJ15951.1 - 0.0088 15.0 0.4 0.009 14.9 0.3 1.0 1 0 0 1 1 1 1 Timeless protein C terminal region SLAIN PF15301.1 OAJ15951.1 - 0.033 13.3 2.7 0.037 13.1 1.9 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family CENP-B_dimeris PF09026.5 OAJ15951.1 - 0.042 14.0 0.5 0.052 13.7 0.3 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Prok-TraM PF09228.5 OAJ15951.1 - 0.059 13.5 0.0 0.065 13.3 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Nucleoplasmin PF03066.10 OAJ15951.1 - 0.077 12.5 1.3 0.086 12.3 0.9 1.1 1 0 0 1 1 1 0 Nucleoplasmin Ribosomal_60s PF00428.14 OAJ15951.1 - 0.095 13.1 0.6 0.12 12.7 0.4 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein HATPase_c PF02518.21 OAJ15952.1 - 2.8e-31 107.5 0.1 2.8e-28 97.8 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAJ15952.1 - 5.1e-24 84.4 0.3 1.2e-23 83.2 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.5 OAJ15952.1 - 1.8e-23 82.6 2.3 2.4e-11 43.6 0.0 6.2 5 1 0 5 5 5 3 PAS fold HisKA PF00512.20 OAJ15952.1 - 2.3e-20 72.3 0.1 6e-20 71.0 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 OAJ15952.1 - 2.9e-17 62.9 0.0 1.8e-10 41.0 0.0 4.6 4 1 0 4 4 4 3 PAS domain PAS PF00989.19 OAJ15952.1 - 1.4e-13 50.6 0.2 0.0056 16.4 0.0 5.7 6 1 0 6 6 6 3 PAS fold PAS_3 PF08447.6 OAJ15952.1 - 1.6e-12 47.3 0.2 4.8e-12 45.8 0.1 1.9 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 OAJ15952.1 - 0.00094 18.9 0.0 4.5 7.2 0.0 4.2 4 0 0 4 4 4 1 PAS domain HATPase_c_3 PF13589.1 OAJ15952.1 - 0.0035 16.9 0.2 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.1 OAJ15952.1 - 0.14 12.4 0.0 96 3.3 0.0 4.0 4 0 0 4 4 4 0 PAS domain Mto2_bdg PF12808.2 OAJ15976.1 - 0.012 15.6 0.1 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region ADIP PF11559.3 OAJ15976.1 - 0.032 14.1 0.8 0.041 13.7 0.5 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 OAJ15976.1 - 0.056 13.2 0.1 0.067 13.0 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SNF5 PF04855.7 OAJ16007.1 - 4.2e-69 232.7 1.8 7.8e-69 231.8 1.2 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 OAJ16007.1 - 0.003 16.8 1.6 0.013 14.8 1.1 2.1 1 0 0 1 1 1 1 GATA zinc finger TolB_N PF04052.8 OAJ16007.1 - 0.1 12.6 0.2 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 TolB amino-terminal domain FYDLN_acid PF09538.5 OAJ16007.1 - 0.18 12.4 0.0 0.18 12.4 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Inhibitor_I53 PF11714.3 OAJ16008.1 - 0.0019 18.1 0.9 0.0019 18.1 0.6 1.8 2 0 0 2 2 2 1 Thrombin inhibitor Madanin SWIM PF04434.12 OAJ16034.1 - 0.011 15.1 0.6 0.024 14.1 0.4 1.5 1 0 0 1 1 1 0 SWIM zinc finger Iso_dh PF00180.15 OAJ16056.1 - 7.3e-78 261.9 0.0 9.4e-78 261.5 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TMEM51 PF15345.1 OAJ16057.1 - 0.38 10.3 9.2 0.68 9.5 6.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 DUF1387 PF07139.6 OAJ16057.1 - 3.2 7.2 6.3 4.6 6.7 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Spt20 PF12090.3 OAJ16057.1 - 4.7 6.5 8.2 1.4 8.2 2.5 2.1 2 0 0 2 2 2 0 Spt20 family Ribonuclease_T2 PF00445.13 OAJ16058.1 - 3.8e-35 121.2 0.1 5.3e-35 120.7 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family GFO_IDH_MocA PF01408.17 OAJ16059.1 - 7.8e-18 65.1 0.1 1.2e-17 64.5 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold RhoGEF PF00621.15 OAJ16087.1 - 9.6e-13 48.3 0.0 5.3e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain RVT_1 PF00078.22 OAJ16110.1 - 4.1e-18 65.5 0.0 7.1e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ16110.1 - 1.9e-15 56.9 0.0 3.6e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain AAA PF00004.24 OAJ16111.1 - 7e-09 35.9 0.1 2.8e-08 34.0 0.0 1.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mito_carr PF00153.22 OAJ16111.1 - 1.6e-08 34.1 0.0 3.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial carrier protein AAA_22 PF13401.1 OAJ16111.1 - 1.7e-05 24.9 0.0 3.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ16111.1 - 3.6e-05 23.6 0.0 6.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ16111.1 - 0.0011 18.7 0.7 0.0026 17.4 0.5 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 OAJ16111.1 - 0.0012 18.8 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 OAJ16111.1 - 0.0016 18.1 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 OAJ16111.1 - 0.0041 16.5 0.0 0.0087 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 OAJ16111.1 - 0.0067 16.3 0.0 0.019 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ16111.1 - 0.011 16.6 0.0 0.023 15.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 OAJ16111.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 OAJ16111.1 - 0.077 12.4 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.1 OAJ16111.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 OAJ16111.1 - 0.2 11.2 0.0 0.5 9.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain Orthopox_F8 PF05886.6 OAJ16144.1 - 0.0057 16.4 6.1 0.14 12.0 1.5 3.3 2 0 0 2 2 2 2 Orthopoxvirus F8 protein DUF3381 PF11861.3 OAJ16145.1 - 0.32 10.4 1.4 0.33 10.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF619 PF04768.8 OAJ16146.1 - 2.4e-28 98.6 0.0 2.5e-19 69.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF619) DDE_1 PF03184.14 OAJ16174.1 - 3e-33 114.7 0.0 5.3e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAJ16174.1 - 4.9e-06 26.2 0.0 1.5e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 OAJ16174.1 - 0.0098 15.4 0.1 0.03 13.8 0.1 1.8 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Asp-B-Hydro_N PF05279.6 OAJ16174.1 - 3.9 7.2 25.7 6.2 6.5 17.8 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PHD PF00628.24 OAJ16175.1 - 9.8e-05 21.9 8.1 9.8e-05 21.9 5.6 1.9 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.1 OAJ16175.1 - 0.14 12.1 2.7 2.9 7.9 0.6 2.3 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 OAJ16175.1 - 0.38 10.9 3.4 4.3 7.5 0.8 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain rve PF00665.21 OAJ16176.1 - 1.1e-07 31.9 0.0 3.5e-07 30.3 0.0 2.0 2 1 0 2 2 2 1 Integrase core domain HTH_21 PF13276.1 OAJ16176.1 - 0.014 15.3 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 HTH-like domain CPSase_L_D3 PF02787.14 OAJ16176.1 - 0.076 12.7 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain WD40 PF00400.27 OAJ16201.1 - 6.6e-16 57.5 0.8 2.1e-05 24.1 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat p450 PF00067.17 OAJ16202.1 - 5.1e-64 216.5 0.0 1.1e-63 215.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 OAJ16203.1 - 2.6e-63 214.1 0.0 6.2e-63 212.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DUF4611 PF15387.1 OAJ16227.1 - 5.7 7.1 27.4 6.1 7.0 4.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Kinesin PF00225.18 OAJ16228.1 - 1.8e-71 240.5 0.5 3.4e-43 147.6 0.0 2.9 3 0 0 3 3 3 2 Kinesin motor domain Abhydrolase_6 PF12697.2 OAJ16261.1 - 3.3e-08 33.7 1.1 0.00055 19.8 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family DUF1749 PF08538.5 OAJ16261.1 - 1.1e-06 27.7 0.0 2e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.2 OAJ16261.1 - 3.8e-06 26.7 0.1 5.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 OAJ16261.1 - 0.18 10.8 0.0 0.34 9.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) RVT_3 PF13456.1 OAJ16292.1 - 0.033 13.9 0.0 0.098 12.4 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase-like Histone PF00125.19 OAJ16325.1 - 1.8e-27 95.2 0.6 2.9e-27 94.5 0.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ16325.1 - 1.8e-05 24.7 0.0 2.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAJ16325.1 - 0.0004 20.3 0.1 0.00078 19.4 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 OAJ16325.1 - 0.047 12.9 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Transposase_21 PF02992.9 OAJ16328.1 - 1.1e-19 70.4 0.0 1.9e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ16328.1 - 0.0025 17.2 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Zn_clus PF00172.13 OAJ16358.1 - 5e-07 29.5 11.1 9.6e-07 28.6 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Telomerase_RBD PF12009.3 OAJ16359.1 - 8.9e-36 122.8 0.0 1.9e-35 121.7 0.0 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 OAJ16359.1 - 1e-12 47.8 0.1 4.9e-12 45.6 0.0 2.2 3 1 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Macin PF14865.1 OAJ16389.1 - 2.5 8.2 13.9 0.15 12.1 1.8 2.7 2 2 0 2 2 2 0 Macin Peroxin-3 PF04882.7 OAJ16390.1 - 8.5e-93 311.4 0.1 3.2e-92 309.5 0.0 1.8 1 1 0 1 1 1 1 Peroxin-3 EXS PF03124.9 OAJ16415.1 - 6.4e-89 298.3 26.4 8.6e-89 297.9 18.3 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 OAJ16415.1 - 1.4e-24 87.3 1.4 1.4e-24 87.3 1.0 1.6 2 0 0 2 2 2 1 SPX domain MMR_HSR1 PF01926.18 OAJ16416.1 - 1.4e-17 63.6 0.1 3.4e-14 52.7 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ16416.1 - 1.8e-07 30.5 0.2 1.3e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 OAJ16416.1 - 8.6e-05 22.4 0.6 0.077 12.8 0.1 3.1 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 OAJ16416.1 - 9e-05 21.9 0.0 0.0064 15.9 0.0 2.9 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 OAJ16416.1 - 0.0082 15.3 0.1 0.018 14.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 KAP_NTPase PF07693.9 OAJ16416.1 - 0.066 12.1 0.1 0.3 10.0 0.0 2.0 2 0 0 2 2 2 0 KAP family P-loop domain MULE PF10551.4 OAJ16447.1 - 3.4e-15 55.9 0.1 6.6e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 OAJ16447.1 - 9.2e-07 29.3 1.6 2.1e-06 28.1 1.1 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain Transposase_mut PF00872.13 OAJ16447.1 - 8.6e-06 24.5 0.0 1.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_IS240 PF13610.1 OAJ16447.1 - 0.0014 18.5 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 DDE domain AFT PF08731.6 OAJ16447.1 - 0.11 12.7 2.0 0.15 12.2 0.5 1.9 2 1 0 2 2 2 0 Transcription factor AFT DUF1722 PF08349.6 OAJ16447.1 - 0.11 12.4 0.3 0.22 11.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) gp12-short_mid PF09089.5 OAJ16447.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Phage short tail fibre protein gp12, middle domain SWIM PF04434.12 OAJ16448.1 - 0.0045 16.4 0.8 0.008 15.6 0.6 1.4 1 0 0 1 1 1 1 SWIM zinc finger PIF1 PF05970.9 OAJ16479.1 - 2e-105 352.7 0.0 2.7e-105 352.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ16479.1 - 7.8e-59 198.4 0.0 1.4e-58 197.6 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 OAJ16479.1 - 8.4e-06 25.4 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 OAJ16479.1 - 5.2e-05 21.2 0.0 0.00011 20.1 0.0 1.4 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 OAJ16479.1 - 0.0033 17.5 0.0 0.0083 16.2 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain T2SE PF00437.15 OAJ16479.1 - 0.015 14.2 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 OAJ16479.1 - 0.034 13.8 0.1 0.1 12.3 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain TrwB_AAD_bind PF10412.4 OAJ16479.1 - 0.038 12.6 0.1 0.17 10.4 0.0 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.7 OAJ16479.1 - 0.073 12.1 0.0 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.4 OAJ16479.1 - 0.16 10.9 0.0 0.31 9.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CorA PF01544.13 OAJ16508.1 - 2e-08 33.6 4.5 4.4e-08 32.4 3.1 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Sporozoite_P67 PF05642.6 OAJ16508.1 - 4.8 4.9 7.9 7.2 4.3 5.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Epimerase PF01370.16 OAJ16510.1 - 2.6e-39 135.0 0.0 3.8e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 OAJ16510.1 - 2.8e-24 84.8 0.0 4.6e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 OAJ16510.1 - 4.3e-12 45.3 0.0 1.5e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 OAJ16510.1 - 2.4e-08 33.1 0.0 4.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 OAJ16510.1 - 4e-08 32.4 0.1 6.6e-08 31.7 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 OAJ16510.1 - 2.3e-07 30.8 0.0 4.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 OAJ16510.1 - 1.1e-06 27.7 0.0 2.3e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 OAJ16510.1 - 4.3e-06 26.8 0.0 0.00024 21.1 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 OAJ16510.1 - 1.3e-05 24.9 0.0 3.5e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 KR domain Ribonuc_L-PSP PF01042.16 OAJ16510.1 - 0.036 13.8 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 Endoribonuclease L-PSP ATP-synt_C PF00137.16 OAJ16567.1 - 2.8e-29 100.7 34.8 7.9e-18 64.1 9.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Fe-S_biosyn PF01521.15 OAJ16568.1 - 0.00019 21.3 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Cation_efflux PF01545.16 OAJ16569.1 - 1.1e-09 37.8 0.3 2e-09 36.9 0.2 1.4 1 0 0 1 1 1 1 Cation efflux family Transposase_20 PF02371.11 OAJ16569.1 - 0.0019 18.2 0.7 0.005 16.9 0.5 1.6 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DNA_pol_delta_4 PF04081.8 OAJ16570.1 - 1.1e-17 64.4 0.0 1.5e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Cutinase PF01083.17 OAJ16594.1 - 3.1e-27 95.4 0.0 3.8e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 OAJ16594.1 - 0.003 17.0 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 OAJ16594.1 - 0.016 14.7 0.1 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ16594.1 - 0.029 14.1 0.1 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF218 PF02698.12 OAJ16595.1 - 0.0058 16.1 0.4 0.2 11.1 0.0 2.6 3 0 0 3 3 3 2 DUF218 domain Pkinase PF00069.20 OAJ16596.1 - 1.3e-59 201.5 0.0 1.2e-58 198.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.3 OAJ16596.1 - 7e-42 143.2 0.0 1.2e-37 129.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.12 OAJ16596.1 - 2e-38 131.9 0.0 3.8e-38 131.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ16596.1 - 0.0002 20.4 0.0 0.65 8.8 0.0 2.7 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 OAJ16596.1 - 0.079 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arrestin_C PF02752.17 OAJ16625.1 - 1.8e-07 31.3 0.0 6.9e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 OAJ16625.1 - 0.00072 19.3 0.1 0.44 10.3 0.0 3.1 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain NTR2 PF15458.1 OAJ16625.1 - 0.087 12.0 0.3 7.6 5.6 0.3 2.7 3 0 0 3 3 3 0 Nineteen complex-related protein 2 Peptidase_S10 PF00450.17 OAJ16626.1 - 2.6e-90 303.5 0.0 3.5e-90 303.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase FF PF01846.14 OAJ16657.1 - 4.9e-17 61.6 14.7 1.1e-07 31.6 0.2 4.9 4 1 0 4 4 4 4 FF domain Glyco_trans_4_3 PF12000.3 OAJ16657.1 - 0.042 13.4 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Gkycosyl transferase family 4 group DUF3391 PF11871.3 OAJ16657.1 - 3.4 7.8 13.0 14 5.8 4.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) Oxysterol_BP PF01237.13 OAJ16658.1 - 1.3e-110 369.2 0.3 3.2e-110 367.9 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 OAJ16658.1 - 4e-16 58.8 0.0 7.7e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 OAJ16658.1 - 0.00013 22.1 0.0 0.00031 20.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 OAJ16658.1 - 0.01 16.0 0.7 0.039 14.1 0.5 1.9 1 1 1 2 2 2 0 Pleckstrin homology domain MOZ_SAS PF01853.13 OAJ16659.1 - 1.7e-82 275.2 0.1 2.5e-82 274.7 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 OAJ16659.1 - 3e-19 68.4 0.1 1.2e-18 66.5 0.1 2.1 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Daxx PF03344.10 OAJ16659.1 - 0.87 8.0 22.9 0.069 11.6 9.2 2.4 2 0 0 2 2 2 0 Daxx Family RXT2_N PF08595.6 OAJ16659.1 - 8.4 6.1 13.0 0.93 9.2 3.3 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.1 OAJ16659.1 - 9.1 5.9 11.7 1.6 8.4 3.9 2.6 2 0 0 2 2 2 0 FAM176 family DUF2919 PF11143.3 OAJ16751.1 - 0.18 11.6 3.6 0.61 9.9 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) MPC PF03650.8 OAJ16751.1 - 0.22 11.4 1.2 0.25 11.2 0.3 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0041) Tmemb_14 PF03647.8 OAJ16752.1 - 6.3e-16 58.5 9.8 8e-16 58.2 6.8 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF155 PF02582.9 OAJ16753.1 - 8e-52 175.6 0.0 1.2e-51 175.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 COLFI PF01410.13 OAJ16754.1 - 0.046 13.1 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain VHS PF00790.14 OAJ16755.1 - 1.7e-35 121.7 1.7 2.3e-35 121.2 0.0 2.0 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 OAJ16755.1 - 2.7e-16 59.2 9.3 5e-16 58.3 6.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 OAJ16755.1 - 5.2e-05 22.4 6.7 0.0044 16.4 0.6 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.11 OAJ16755.1 - 9.7e-05 22.2 2.8 0.0002 21.2 2.0 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger DUF3602 PF12223.3 OAJ16755.1 - 0.00016 22.0 1.2 0.00016 22.0 0.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3602) zf-RING_5 PF14634.1 OAJ16755.1 - 1.2 8.9 11.4 1.9 8.2 7.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DDE_Tnp_4 PF13359.1 OAJ16790.1 - 2.3e-21 76.0 0.0 4.2e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease IncA PF04156.9 OAJ16791.1 - 0.017 14.6 0.4 0.029 13.9 0.3 1.3 1 0 0 1 1 1 0 IncA protein DUF3425 PF11905.3 OAJ16792.1 - 3.4e-10 39.9 0.0 1e-09 38.3 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 OAJ16792.1 - 3.3e-07 30.1 5.7 9e-07 28.7 3.9 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAJ16792.1 - 1.4 8.7 7.4 1.1 9.1 2.3 2.3 2 0 0 2 2 2 0 Basic region leucine zipper NAD_binding_10 PF13460.1 OAJ16827.1 - 4.1e-09 36.6 0.0 1.4e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAJ16827.1 - 8.6e-05 22.0 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAJ16827.1 - 0.023 13.4 0.0 0.037 12.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 OAJ16827.1 - 0.026 13.4 0.0 0.33 9.8 0.0 2.4 2 1 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.20 OAJ16827.1 - 0.07 13.0 0.1 0.21 11.4 0.0 1.9 1 1 0 1 1 1 0 short chain dehydrogenase Nop14 PF04147.7 OAJ16828.1 - 3.5e-228 759.6 4.2 4.9e-228 759.1 2.9 1.2 1 0 0 1 1 1 1 Nop14-like family 2OG-FeII_Oxy_3 PF13640.1 OAJ16861.1 - 3.4e-09 37.0 0.0 6.2e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 OAJ16861.1 - 1.9e-06 27.3 0.0 4.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Exc PF07825.6 OAJ16861.1 - 0.097 12.4 0.1 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Excisionase-like protein PACT_coil_coil PF10495.4 OAJ16862.1 - 1.6e-11 43.9 0.1 6.1e-11 42.0 0.1 2.1 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.4 OAJ16862.1 - 0.0069 16.2 87.7 0.59 9.9 2.2 6.4 3 1 3 6 6 6 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 OAJ16862.1 - 0.008 15.3 13.9 0.046 12.9 1.1 4.7 2 2 2 5 5 5 2 Reovirus sigma C capsid protein DUF948 PF06103.6 OAJ16862.1 - 5.1 7.0 24.8 2.9 7.7 0.3 6.5 6 2 2 8 8 8 0 Bacterial protein of unknown function (DUF948) HrpB2 PF09487.5 OAJ16862.1 - 5.2 7.3 9.2 13 6.0 0.3 3.6 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB2) GAS PF13851.1 OAJ16862.1 - 5.2 6.1 75.9 0.11 11.7 8.2 5.1 3 2 1 4 4 4 0 Growth-arrest specific micro-tubule binding Collagen PF01391.13 OAJ16863.1 - 3.4e-20 71.3 72.0 2.4e-08 33.3 15.9 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Dimer_Tnp_hAT PF05699.9 OAJ16897.1 - 1.9e-12 46.6 0.0 3.4e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.20 OAJ16898.1 - 3.8e-40 137.6 0.0 6e-40 137.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ16898.1 - 1.1e-23 83.5 0.0 1.6e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RMMBL PF07521.7 OAJ16960.1 - 0.067 13.0 0.6 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase RNase_HII PF01351.13 OAJ16987.1 - 4.6e-42 143.9 0.0 3.7e-38 131.1 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease HII DNA_pol_A_exo1 PF01612.15 OAJ16988.1 - 3.6e-38 130.7 0.1 5.3e-38 130.2 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 OAJ16988.1 - 3.7e-15 56.0 0.0 8.2e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 OAJ16988.1 - 9.1e-12 44.5 0.2 1.8e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 HRDC domain Hepar_II_III PF07940.8 OAJ16989.1 - 0.038 13.8 0.1 2.1 8.1 0.1 2.5 2 0 0 2 2 2 0 Heparinase II/III-like protein SDA1 PF05285.7 OAJ17019.1 - 0.0037 16.5 15.7 0.005 16.1 10.9 1.3 1 0 0 1 1 1 1 SDA1 Pox_Ag35 PF03286.9 OAJ17019.1 - 0.011 15.2 12.9 0.019 14.5 9.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.7 OAJ17019.1 - 0.016 13.1 20.5 0.021 12.8 14.2 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 OAJ17019.1 - 0.037 13.1 22.2 0.058 12.5 15.4 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cwf_Cwc_15 PF04889.7 OAJ17019.1 - 0.054 13.1 12.8 0.092 12.4 8.9 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Myb_DNA-bind_3 PF12776.2 OAJ17019.1 - 0.055 14.1 0.2 0.095 13.3 0.1 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Cytomega_UL84 PF06284.6 OAJ17019.1 - 0.061 11.7 4.7 0.083 11.2 3.3 1.4 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein BSP_II PF05432.6 OAJ17019.1 - 0.095 11.9 26.7 0.21 10.8 18.5 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TLP-20 PF06088.6 OAJ17019.1 - 0.26 10.9 5.4 0.48 10.0 3.7 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2457 PF10446.4 OAJ17019.1 - 0.38 9.4 28.2 0.62 8.7 19.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleo_P87 PF07267.6 OAJ17019.1 - 0.72 8.4 6.7 0.95 8.0 4.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ycf1 PF05758.7 OAJ17019.1 - 1.1 6.8 7.1 1.4 6.5 4.9 1.2 1 0 0 1 1 1 0 Ycf1 CDC27 PF09507.5 OAJ17019.1 - 1.3 8.1 18.4 2 7.5 12.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Astro_capsid PF03115.9 OAJ17019.1 - 1.8 6.6 6.5 2.6 6.1 4.5 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor NARP1 PF12569.3 OAJ17019.1 - 1.8 7.1 11.2 2.9 6.5 7.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FYDLN_acid PF09538.5 OAJ17019.1 - 2.2 8.9 23.2 4.8 7.8 16.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Daxx PF03344.10 OAJ17019.1 - 3.3 6.0 30.5 4.6 5.6 21.1 1.1 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 OAJ17019.1 - 3.9 6.4 35.1 17 4.3 24.3 1.9 1 1 0 1 1 1 0 BUD22 Vfa1 PF08432.5 OAJ17019.1 - 5.2 7.0 14.4 0.98 9.4 7.6 1.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 OAJ17019.1 - 7 5.9 23.0 13 5.0 16.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNA_pol_3_Rpc31 PF11705.3 OAJ17019.1 - 9.7 6.0 29.9 5.8 6.7 19.4 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 PAF-AH_p_II PF03403.8 OAJ17059.1 - 1.1e-37 129.2 0.0 6.8e-20 70.6 0.2 3.0 2 2 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 OAJ17059.1 - 5.4e-10 39.2 0.3 1.1e-08 34.8 0.2 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ17059.1 - 0.028 14.2 0.2 0.058 13.2 0.1 1.4 1 0 0 1 1 1 0 Putative lysophospholipase HSP70 PF00012.15 OAJ17060.1 - 0 1157.7 17.7 5.3e-261 866.8 7.9 3.0 3 0 0 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.8 OAJ17060.1 - 4.1e-25 88.0 5.5 9.7e-13 47.4 0.4 3.4 3 0 0 3 3 3 3 MreB/Mbl protein FtsA PF14450.1 OAJ17060.1 - 3.6e-05 23.5 4.6 0.49 10.2 0.2 4.1 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.13 OAJ17060.1 - 0.00024 20.2 11.0 0.88 8.6 0.1 4.0 3 1 0 3 3 3 3 Hydantoinase/oxoprolinase DDR PF08841.5 OAJ17060.1 - 0.0008 18.3 1.2 1.7 7.3 0.0 3.4 4 0 0 4 4 4 2 Diol dehydratase reactivase ATPase-like domain Seryl_tRNA_N PF02403.17 OAJ17060.1 - 0.018 15.0 7.5 0.047 13.7 5.2 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain NrfD PF03916.9 OAJ17061.1 - 0.015 14.6 6.5 0.052 12.9 0.2 2.0 1 1 1 2 2 2 0 Polysulphide reductase, NrfD VirB3 PF05101.8 OAJ17061.1 - 3 7.9 5.6 1.8 8.5 0.4 2.1 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein DUF588 PF04535.7 OAJ17091.1 - 0.081 12.4 0.8 0.12 11.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) DUF588 PF04535.7 OAJ17094.1 - 0.081 12.4 0.8 0.12 11.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) Vps8 PF12816.2 OAJ17126.1 - 2e-50 170.7 0.0 3.1e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 OAJ17126.1 - 0.02 14.5 0.2 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Region in Clathrin and VPS DUF605 PF04652.11 OAJ17126.1 - 8 5.7 23.6 19 4.5 0.3 2.6 2 0 0 2 2 2 0 Vta1 like Kin17_mid PF10357.4 OAJ17127.1 - 2.8e-44 149.8 0.1 5.6e-44 148.8 0.0 1.5 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 OAJ17127.1 - 0.037 14.1 2.3 0.066 13.3 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 OAJ17127.1 - 0.11 12.6 1.3 0.17 11.9 0.1 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Mito_carr PF00153.22 OAJ17157.1 - 4.5e-64 212.2 3.4 2.4e-21 75.2 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein zf-CCHC_4 PF14392.1 OAJ17158.1 - 0.8 9.4 3.3 5.7 6.7 0.2 2.3 2 0 0 2 2 2 0 Zinc knuckle Ycf1 PF05758.7 OAJ17159.1 - 9.5 3.7 12.1 14 3.1 8.4 1.2 1 0 0 1 1 1 0 Ycf1 Proteasome PF00227.21 OAJ17160.1 - 9.7e-51 171.7 0.0 1.3e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAJ17160.1 - 1.2e-11 43.7 0.1 2e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature VPS9 PF02204.13 OAJ17187.1 - 2.3e-18 66.1 0.0 3.4e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Transferase PF02458.10 OAJ17188.1 - 1.1e-08 33.9 0.0 0.00077 18.0 0.0 3.0 3 0 0 3 3 3 3 Transferase family EutH PF04346.7 OAJ17219.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.0 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH CAF-1_p150 PF11600.3 OAJ17220.1 - 0.016 14.5 24.1 0.043 13.2 16.7 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SpoVR PF04293.8 OAJ17220.1 - 4 5.6 10.5 6.1 5.0 7.3 1.2 1 0 0 1 1 1 0 SpoVR like protein MFS_1 PF07690.11 OAJ17221.1 - 3.7e-38 131.1 39.9 3.7e-38 131.1 27.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sin_N PF04801.8 OAJ17253.1 - 8.5e-15 54.5 0.3 3.6e-13 49.1 0.0 2.4 2 0 0 2 2 2 2 Sin-like protein conserved region RNase_PH PF01138.16 OAJ17254.1 - 5.9e-16 58.9 0.0 1.2e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_S9_N PF02897.10 OAJ17255.1 - 7.8e-78 261.8 0.1 1e-77 261.5 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 OAJ17255.1 - 1.2e-47 161.9 0.0 2e-47 161.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 OAJ17255.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Methyltransf_6 PF03737.10 OAJ17255.1 - 0.081 12.7 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Demethylmenaquinone methyltransferase Imm21 PF15569.1 OAJ17255.1 - 0.12 12.1 1.1 6.4 6.6 0.1 2.6 2 0 0 2 2 2 0 Immunity protein 21 Adap_comp_sub PF00928.16 OAJ17256.1 - 3.3e-40 137.8 0.0 4.4e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family stn_TNFRSF12A PF12191.3 OAJ17289.1 - 0.43 10.6 5.1 0.46 10.5 3.6 1.0 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain zf-RING_2 PF13639.1 OAJ17290.1 - 0.038 13.8 0.3 6.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Ring finger domain MSP1_C PF07462.6 OAJ17290.1 - 1.6 7.0 1.6 2.6 6.3 1.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DAGK_cat PF00781.19 OAJ17291.1 - 3.1e-11 42.8 0.0 7.2e-11 41.6 0.0 1.6 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Nucleoplasmin PF03066.10 OAJ17326.1 - 0.36 10.3 5.8 0.79 9.2 4.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 OAJ17326.1 - 2 6.3 4.4 2.9 5.8 3.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 OAJ17326.1 - 2.2 7.8 6.9 0.79 9.2 2.5 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region NOA36 PF06524.7 OAJ17326.1 - 7.1 5.7 7.2 14 4.8 5.0 1.4 1 0 0 1 1 1 0 NOA36 protein Atg14 PF10186.4 OAJ17327.1 - 0.28 10.1 8.2 0.48 9.3 5.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TSA PF03249.8 OAJ17327.1 - 0.3 9.5 9.4 0.49 8.8 6.5 1.2 1 0 0 1 1 1 0 Type specific antigen Pex14_N PF04695.8 OAJ17327.1 - 1.3 9.1 9.4 0.24 11.4 3.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CPSF_A PF03178.10 OAJ17359.1 - 1.5e-61 208.2 0.0 2.5e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region N2227 PF07942.7 OAJ17360.1 - 1.3e-87 293.2 0.0 1.8e-87 292.7 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 OAJ17360.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Apolipoprotein PF01442.13 OAJ17394.1 - 0.018 14.5 2.0 0.018 14.5 1.4 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DASH_Dad2 PF08654.5 OAJ17394.1 - 0.045 13.7 0.7 0.045 13.7 0.5 2.2 1 1 1 2 2 2 0 DASH complex subunit Dad2 DUF883 PF05957.8 OAJ17394.1 - 0.4 11.1 5.7 3.1 8.2 1.3 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) OmpH PF03938.9 OAJ17394.1 - 0.45 10.4 7.2 4.5 7.1 0.0 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.7 OAJ17394.1 - 2 8.7 5.3 30 4.9 3.6 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein UBN2 PF14223.1 OAJ17395.1 - 0.013 15.3 1.9 0.019 14.7 1.3 1.3 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type SUV3_C PF12513.3 OAJ17395.1 - 0.021 14.2 0.1 0.32 10.4 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal DUF2802 PF10975.3 OAJ17395.1 - 0.36 10.6 4.9 0.89 9.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) DUF1151 PF06625.6 OAJ17395.1 - 6.1 6.6 9.7 3.2 7.5 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1151) T2SF PF00482.18 OAJ17396.1 - 0.037 13.9 0.1 0.12 12.2 0.1 1.9 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Myb_DNA-bind_4 PF13837.1 OAJ17396.1 - 0.039 14.0 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Abhydrolase_5 PF12695.2 OAJ17431.1 - 0.00079 19.1 0.0 0.0039 16.9 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Nup35_RRM PF05172.8 OAJ17431.1 - 0.036 13.8 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PGAP1 PF07819.8 OAJ17431.1 - 0.043 13.4 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein ASFV_L11L PF05293.6 OAJ17431.1 - 2 8.6 3.9 0.65 10.1 0.1 2.2 3 0 0 3 3 3 0 African swine fever virus (ASFV) L11L protein SIS PF01380.17 OAJ17465.1 - 2.2e-62 208.4 0.1 3e-34 117.4 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 OAJ17465.1 - 1e-29 103.3 0.1 2.6e-18 65.8 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 OAJ17465.1 - 1.9e-18 66.7 0.0 3.8e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 OAJ17465.1 - 2.8e-13 49.6 0.0 5.9e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 OAJ17465.1 - 6.9e-07 28.2 0.0 9.8e-07 27.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 OAJ17465.1 - 0.0011 18.6 0.0 0.05 13.3 0.0 3.0 3 1 1 4 4 4 1 SIS domain Plasmid_Txe PF06769.8 OAJ17465.1 - 0.14 12.0 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Plasmid encoded toxin Txe P16-Arc PF04699.9 OAJ17466.1 - 5.3e-48 162.8 0.0 5.9e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Ras PF00071.17 OAJ17500.1 - 8.3e-28 96.8 0.0 1.4e-26 92.8 0.0 2.1 2 0 0 2 2 2 1 Ras family Miro PF08477.8 OAJ17500.1 - 1.4e-09 38.5 0.0 2.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ17500.1 - 0.00014 21.1 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ17500.1 - 0.001 18.2 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Nucleoplasmin PF03066.10 OAJ17500.1 - 5 6.6 16.7 0.77 9.2 1.2 3.6 4 0 0 4 4 4 0 Nucleoplasmin Cation_efflux PF01545.16 OAJ17501.1 - 3.2e-26 92.0 6.0 3.8e-26 91.8 4.1 1.1 1 0 0 1 1 1 1 Cation efflux family BPL_LplA_LipB PF03099.14 OAJ17502.1 - 0.00013 21.9 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family SDA1 PF05285.7 OAJ17540.1 - 0.053 12.7 7.4 3.6 6.7 4.1 2.3 2 0 0 2 2 2 0 SDA1 DUF1687 PF07955.6 OAJ17541.1 - 7.7e-10 38.8 0.1 0.0018 18.2 0.0 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF1687) DUF2611 PF11022.3 OAJ17581.1 - 3.3e-13 49.5 1.4 1.3e-12 47.5 1.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2611) DUF533 PF04391.7 OAJ17581.1 - 0.077 12.3 0.2 0.09 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Cyt-b5 PF00173.23 OAJ17582.1 - 3.8e-17 61.8 0.0 5.2e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain OB_NTP_bind PF07717.11 OAJ17583.1 - 1.2e-27 95.9 0.0 2.6e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 OAJ17583.1 - 2.8e-27 94.6 0.1 8e-27 93.2 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ17583.1 - 6.9e-12 45.0 0.0 1.6e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ17583.1 - 3.3e-05 23.4 0.2 7.6e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 OAJ17583.1 - 5.9e-05 22.1 0.0 0.00016 20.6 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 OAJ17583.1 - 0.00037 20.6 0.0 0.00096 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 OAJ17583.1 - 0.043 14.1 0.3 0.43 10.8 0.2 2.4 1 1 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.1 OAJ17583.1 - 0.055 13.5 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 OAJ17583.1 - 0.057 13.0 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 OAJ17583.1 - 0.13 12.1 0.1 1.6 8.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain ATP11 PF06644.6 OAJ17583.1 - 0.27 10.7 5.6 0.45 9.9 0.0 2.5 2 0 0 2 2 2 0 ATP11 protein AAA_19 PF13245.1 OAJ17583.1 - 0.47 10.2 6.1 0.049 13.3 0.3 2.3 3 0 0 3 3 3 0 Part of AAA domain NuA4 PF09340.5 OAJ17584.1 - 7.2e-20 70.4 0.0 1.5e-19 69.4 0.0 1.5 1 1 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Bac_surface_Ag PF01103.18 OAJ17585.1 - 2.3e-25 89.7 0.4 4.4e-25 88.8 0.2 1.4 1 1 0 1 1 1 1 Surface antigen Cyclin PF08613.6 OAJ17623.1 - 3.2e-14 53.6 0.4 1.3e-11 45.1 0.0 2.4 2 0 0 2 2 2 2 Cyclin Ras PF00071.17 OAJ17624.1 - 3.6e-62 208.5 0.1 4.2e-62 208.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ17624.1 - 5.5e-20 72.0 0.0 7.6e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ17624.1 - 2.1e-12 46.6 0.0 2.8e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 OAJ17624.1 - 1.2e-06 28.4 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAJ17624.1 - 1.9e-05 24.2 0.1 7.3e-05 22.2 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 OAJ17624.1 - 9e-05 22.6 0.0 0.00031 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 OAJ17624.1 - 0.002 17.3 0.1 0.0046 16.1 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 OAJ17624.1 - 0.0047 16.1 0.0 0.0068 15.6 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_15 PF13175.1 OAJ17624.1 - 0.015 14.4 0.0 0.018 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.1 OAJ17624.1 - 0.017 15.1 0.5 0.047 13.6 0.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 OAJ17624.1 - 0.031 13.7 0.0 0.088 12.2 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 OAJ17624.1 - 0.034 13.3 0.0 0.082 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 OAJ17624.1 - 0.035 14.3 0.1 0.06 13.6 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 OAJ17624.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 OAJ17624.1 - 0.07 12.8 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 OAJ17624.1 - 0.11 12.4 0.1 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 OAJ17625.1 - 1.6e-26 93.1 0.0 1.4e-11 44.9 0.0 4.2 3 1 0 3 3 3 2 Miro-like protein EF_assoc_2 PF08356.7 OAJ17625.1 - 5.6e-23 80.5 0.0 1.6e-22 79.0 0.0 1.8 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 OAJ17625.1 - 3e-20 71.2 0.0 8.5e-20 69.8 0.0 1.8 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 OAJ17625.1 - 6.2e-16 58.2 0.0 0.00028 20.3 0.0 4.9 5 0 0 5 5 5 3 Ras family MMR_HSR1 PF01926.18 OAJ17625.1 - 2.2e-06 27.6 0.0 0.00028 20.8 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 OAJ17625.1 - 4.3e-06 26.8 0.0 0.066 13.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 OAJ17625.1 - 8.6e-06 25.8 0.7 0.02 14.8 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain EF-hand_7 PF13499.1 OAJ17625.1 - 1.2e-05 25.3 0.3 0.2 11.8 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair Dynamin_N PF00350.18 OAJ17625.1 - 2.6e-05 24.0 0.1 0.27 11.0 0.1 2.5 2 0 0 2 2 2 2 Dynamin family ABC_tran PF00005.22 OAJ17625.1 - 4.4e-05 23.7 0.1 0.03 14.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 OAJ17625.1 - 0.00013 21.3 0.2 0.043 13.3 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 OAJ17625.1 - 0.00023 20.3 0.2 0.0018 17.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 EF-hand_6 PF13405.1 OAJ17625.1 - 0.00039 20.0 6.4 0.08 12.8 0.1 3.1 3 0 0 3 3 2 2 EF-hand domain AIG1 PF04548.11 OAJ17625.1 - 0.00048 19.2 0.1 0.00082 18.5 0.1 1.3 1 0 0 1 1 1 1 AIG1 family NACHT PF05729.7 OAJ17625.1 - 0.00094 18.8 0.2 1.6 8.3 0.0 2.4 2 0 0 2 2 2 2 NACHT domain MobB PF03205.9 OAJ17625.1 - 0.0012 18.5 0.1 0.029 14.0 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 OAJ17625.1 - 0.0067 16.3 0.2 2.9 7.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 OAJ17625.1 - 0.012 15.8 0.1 0.78 9.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 OAJ17625.1 - 0.012 15.4 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 OAJ17625.1 - 0.013 14.4 0.2 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 OAJ17625.1 - 0.018 14.5 0.1 4.6 6.6 0.1 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.13 OAJ17625.1 - 0.02 13.8 0.0 0.075 12.0 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_18 PF13238.1 OAJ17625.1 - 0.021 15.1 0.4 0.8 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 OAJ17625.1 - 0.022 14.2 0.0 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 OAJ17625.1 - 0.024 15.4 0.0 2.8 8.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 OAJ17625.1 - 0.026 14.0 0.1 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 OAJ17625.1 - 0.041 13.4 0.3 22 4.5 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein EF-hand_1 PF00036.27 OAJ17625.1 - 0.042 13.1 9.2 0.35 10.2 0.1 3.5 4 0 0 4 4 3 0 EF hand cobW PF02492.14 OAJ17625.1 - 0.042 13.2 0.1 4.7 6.6 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 OAJ17625.1 - 0.047 13.8 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 OAJ17625.1 - 0.051 13.2 0.1 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase Viral_helicase1 PF01443.13 OAJ17625.1 - 0.065 12.7 0.0 5.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 OAJ17625.1 - 0.11 11.9 0.1 3.8 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 OAJ17625.1 - 0.17 11.3 0.1 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase Arf PF00025.16 OAJ17625.1 - 0.27 10.4 0.0 4.3 6.5 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_23 PF13476.1 OAJ17625.1 - 0.29 11.4 0.3 13 6.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain EF-hand_10 PF14788.1 OAJ17625.1 - 0.35 10.5 0.4 1.2 8.8 0.0 1.9 2 0 0 2 2 2 0 EF hand NB-ARC PF00931.17 OAJ17625.1 - 0.36 9.6 0.0 5.8 5.6 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.12 OAJ17625.1 - 0.45 10.2 0.2 8.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_21 PF13304.1 OAJ17625.1 - 0.48 10.3 0.0 18 5.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.1 OAJ17625.1 - 0.58 9.8 1.2 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair Macoilin PF09726.4 OAJ17625.1 - 0.61 8.2 5.2 0.18 10.0 0.5 2.1 2 0 0 2 2 2 0 Transmembrane protein EF-hand_5 PF13202.1 OAJ17625.1 - 7 6.1 11.9 0.16 11.3 0.1 3.0 3 0 0 3 3 2 0 EF hand Glyco_hydro_45 PF02015.11 OAJ17656.1 - 8.9e-49 166.2 3.3 1.1e-48 165.9 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 CPT PF07931.7 OAJ17657.1 - 0.098 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TFIIA PF03153.8 OAJ17658.1 - 0.0049 16.8 10.1 0.0061 16.5 7.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CENP-T PF15511.1 OAJ17658.1 - 0.047 12.9 12.6 0.062 12.5 8.7 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 OAJ17658.1 - 0.07 11.0 16.1 0.091 10.6 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 OAJ17658.1 - 0.1 10.6 8.5 0.19 9.8 5.9 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 VID27 PF08553.5 OAJ17658.1 - 0.25 9.5 4.3 0.32 9.1 3.0 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Na_trans_assoc PF06512.8 OAJ17658.1 - 0.32 10.9 4.3 0.45 10.4 3.0 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated CDC45 PF02724.9 OAJ17658.1 - 0.76 7.7 8.8 1 7.2 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein LCE PF14672.1 OAJ17658.1 - 2.1 8.8 7.7 1.3 9.5 1.7 2.3 2 0 0 2 2 2 0 Late cornified envelope SURF2 PF05477.6 OAJ17658.1 - 3.1 6.8 8.1 5 6.1 5.6 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CobT PF06213.7 OAJ17658.1 - 3.3 6.7 16.4 6.1 5.8 11.4 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ebola_NP PF05505.7 OAJ17658.1 - 4.4 5.2 8.8 5.6 4.8 6.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Sigma70_ner PF04546.8 OAJ17658.1 - 5.7 6.4 12.8 10 5.6 8.9 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region PPP4R2 PF09184.6 OAJ17658.1 - 6.3 6.2 12.3 10 5.5 8.5 1.3 1 0 0 1 1 1 0 PPP4R2 Glyco_hydro_45 PF02015.11 OAJ17659.1 - 2.4e-51 174.6 5.4 2.9e-51 174.3 3.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 SelP_N PF04592.9 OAJ17659.1 - 5.9 6.2 12.4 10 5.4 8.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Helicase_C PF00271.26 OAJ17695.1 - 5.8e-11 42.1 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ17695.1 - 0.019 14.4 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase SDA1 PF05285.7 OAJ17696.1 - 0.043 13.1 14.3 0.072 12.3 9.9 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 OAJ17696.1 - 0.18 9.8 10.9 0.3 9.0 7.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 OAJ17696.1 - 0.47 8.3 21.4 0.69 7.7 14.8 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 OAJ17696.1 - 0.63 9.6 13.8 1.2 8.6 9.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein DUF605 PF04652.11 OAJ17696.1 - 9.4 5.5 46.8 0.26 10.6 5.5 2.7 3 0 0 3 3 3 0 Vta1 like VTC PF09359.5 OAJ17737.1 - 1e-98 329.8 0.0 2e-98 328.8 0.0 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 OAJ17737.1 - 2.3e-30 106.3 15.4 1.3e-29 103.9 5.9 3.2 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 OAJ17737.1 - 4.3e-12 46.0 1.6 6.5e-12 45.4 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) BRAP2 PF07576.7 OAJ17738.1 - 4.3e-20 71.3 0.0 1e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 OAJ17738.1 - 8.7e-17 60.9 4.5 8.7e-17 60.9 3.1 1.8 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 OAJ17738.1 - 1.1e-08 34.6 10.6 1.1e-08 34.6 7.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 OAJ17738.1 - 7.8e-06 25.9 4.5 7.8e-06 25.9 3.1 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 OAJ17738.1 - 2.9e-05 23.6 9.4 2.9e-05 23.6 6.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ17738.1 - 6.2e-05 22.6 8.3 6.2e-05 22.6 5.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain CENP-Q PF13094.1 OAJ17738.1 - 0.00059 19.9 7.3 0.6 10.1 0.0 2.6 2 0 0 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit zf-RING_UBOX PF13445.1 OAJ17738.1 - 0.00065 19.3 5.4 0.0049 16.5 1.7 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 OAJ17738.1 - 0.00065 19.6 10.1 0.00065 19.6 7.0 2.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ17738.1 - 0.00098 18.7 8.0 0.00098 18.7 5.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAJ17738.1 - 0.0012 18.6 4.0 0.0012 18.6 2.8 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_6 PF14259.1 OAJ17738.1 - 0.0016 18.3 0.0 0.0045 16.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DEC-1_C PF04626.8 OAJ17738.1 - 0.014 15.5 5.4 0.032 14.3 3.7 1.5 1 0 0 1 1 1 0 Dec-1 protein, C terminal region zf-RING_4 PF14570.1 OAJ17738.1 - 0.054 13.0 6.9 0.12 12.0 4.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 OAJ17738.1 - 0.086 12.4 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_RING PF05883.6 OAJ17738.1 - 0.21 11.3 0.6 0.47 10.2 0.4 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Spc24 PF08286.6 OAJ17738.1 - 2.1 8.0 5.3 0.63 9.7 0.1 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 zf-RING_6 PF14835.1 OAJ17738.1 - 5.3 6.8 11.8 0.04 13.6 1.9 2.1 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Cornifin PF02389.10 OAJ17739.1 - 0.0032 17.2 2.9 0.0076 16.0 2.0 1.5 1 1 0 1 1 1 1 Cornifin (SPRR) family Dimer_Tnp_hAT PF05699.9 OAJ17767.1 - 2.2e-14 52.8 0.1 6.5e-14 51.3 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 OAJ17767.1 - 0.0083 15.8 2.1 0.033 13.9 0.6 2.4 2 0 0 2 2 2 1 BED zinc finger IL13 PF03487.8 OAJ17767.1 - 4.4 7.0 6.6 0.62 9.8 0.0 3.0 4 0 0 4 4 4 0 Interleukin-13 Pkinase PF00069.20 OAJ17768.1 - 2.1e-37 128.6 0.0 2.6e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ17768.1 - 3.9e-18 65.4 0.0 6.2e-18 64.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ17768.1 - 1.5e-06 27.4 0.0 4.3e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAJ17768.1 - 3.3e-05 23.7 0.3 0.00011 22.0 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 OAJ17768.1 - 0.0054 16.1 0.0 0.0083 15.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 OAJ17768.1 - 0.027 13.5 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 OAJ17768.1 - 0.075 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.15 OAJ17768.1 - 0.2 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase MULE PF10551.4 OAJ17769.1 - 9.7e-15 54.5 0.0 2.6e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ17769.1 - 0.0022 16.5 0.1 0.0036 15.9 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family FAR1 PF03101.10 OAJ17769.1 - 0.0048 17.3 0.9 0.0084 16.6 0.6 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain Peptidase_C48 PF02902.14 OAJ17808.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain Sensor_TM1 PF13755.1 OAJ17810.1 - 0.017 14.6 0.1 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain Spc97_Spc98 PF04130.8 OAJ17838.1 - 3.4e-36 124.7 0.0 2.4e-17 62.5 0.0 2.3 2 0 0 2 2 2 2 Spc97 / Spc98 family DHHW PF14286.1 OAJ17838.1 - 0.55 9.4 0.1 0.88 8.8 0.1 1.2 1 0 0 1 1 1 0 DHHW protein DNA_pol_phi PF04931.8 OAJ17838.1 - 8 4.0 8.5 12 3.4 5.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi XPG_I_2 PF12813.2 OAJ17839.1 - 1e-05 25.2 0.0 4.2e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 XPG domain containing XPG_N PF00752.12 OAJ17839.1 - 0.00021 21.5 0.0 0.0007 19.8 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 OAJ17839.1 - 0.056 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 XPG I-region K_channel_TID PF07941.6 OAJ17839.1 - 0.36 11.0 6.6 1.5 9.1 4.6 2.0 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain FCH PF00611.18 OAJ17874.1 - 2.2e-16 59.7 0.0 2.2e-16 59.7 0.0 3.0 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SdrG_C_C PF10425.4 OAJ17874.1 - 0.022 14.7 0.5 0.038 13.9 0.3 1.3 1 0 0 1 1 1 0 C-terminus of bacterial fibrinogen-binding adhesin MFS_1 PF07690.11 OAJ17875.1 - 3.8e-30 104.8 27.5 3.8e-30 104.8 19.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily ABC_tran PF00005.22 OAJ17876.1 - 9.5e-45 152.2 0.0 1e-23 84.1 0.0 3.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 OAJ17876.1 - 5.6e-16 59.3 2.8 0.0001 22.4 0.0 4.3 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 OAJ17876.1 - 2.4e-10 40.0 0.1 0.017 14.3 0.0 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAJ17876.1 - 3e-08 34.2 0.0 0.0022 18.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAJ17876.1 - 9e-07 28.3 0.3 0.052 13.0 0.1 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain HEAT PF02985.17 OAJ17876.1 - 2.5e-06 27.0 2.2 1 9.5 0.0 5.8 5 0 0 5 5 5 1 HEAT repeat Chromo PF00385.19 OAJ17876.1 - 7.2e-06 25.5 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Miro PF08477.8 OAJ17876.1 - 9.6e-06 26.0 0.2 0.071 13.6 0.0 3.5 3 0 0 3 3 3 1 Miro-like protein MMR_HSR1 PF01926.18 OAJ17876.1 - 1e-05 25.4 0.0 0.022 14.6 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_15 PF13175.1 OAJ17876.1 - 2.3e-05 23.6 0.0 1.1 8.2 0.0 3.3 2 1 0 3 3 3 2 AAA ATPase domain HEAT_2 PF13646.1 OAJ17876.1 - 2.7e-05 24.3 13.2 0.00047 20.3 0.8 4.7 2 1 1 4 4 3 1 HEAT repeats AAA_22 PF13401.1 OAJ17876.1 - 0.00016 21.8 0.1 2.6 8.1 0.0 4.0 4 1 0 4 4 3 2 AAA domain HEAT_EZ PF13513.1 OAJ17876.1 - 0.00023 21.5 10.3 0.2 12.1 0.1 6.1 4 2 3 7 7 6 1 HEAT-like repeat AAA_10 PF12846.2 OAJ17876.1 - 0.00044 19.7 2.2 0.95 8.8 0.0 4.2 4 1 0 4 4 4 1 AAA-like domain AAA_25 PF13481.1 OAJ17876.1 - 0.00053 19.4 0.1 6.3 6.1 0.0 3.9 4 0 0 4 4 4 0 AAA domain NACHT PF05729.7 OAJ17876.1 - 0.00079 19.1 0.0 1 9.0 0.0 2.8 2 0 0 2 2 2 2 NACHT domain DUF258 PF03193.11 OAJ17876.1 - 0.00088 18.4 0.1 0.056 12.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 OAJ17876.1 - 0.00099 19.1 8.0 0.021 14.7 0.0 4.4 3 1 0 4 4 4 1 AAA ATPase domain AAA_28 PF13521.1 OAJ17876.1 - 0.0011 19.0 0.1 6.7 6.6 0.0 3.7 3 0 0 3 3 3 0 AAA domain ArgK PF03308.11 OAJ17876.1 - 0.0013 17.5 0.2 0.17 10.6 0.0 2.5 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 OAJ17876.1 - 0.0025 18.6 0.0 0.59 10.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAJ17876.1 - 0.0033 17.3 0.0 0.55 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 OAJ17876.1 - 0.0037 17.1 0.0 0.68 9.8 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 OAJ17876.1 - 0.0042 16.6 0.3 1.1 8.8 0.0 3.1 4 0 0 4 4 2 1 AAA domain MobB PF03205.9 OAJ17876.1 - 0.0047 16.6 0.4 2 8.0 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Adaptin_N PF01602.15 OAJ17876.1 - 0.0049 15.2 0.6 0.14 10.4 0.3 2.5 1 1 1 2 2 2 2 Adaptin N terminal region DUF87 PF01935.12 OAJ17876.1 - 0.017 14.9 0.7 7.5 6.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 GTP_EFTU PF00009.22 OAJ17876.1 - 0.022 14.2 0.3 0.74 9.2 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Zeta_toxin PF06414.7 OAJ17876.1 - 0.037 13.1 0.3 12 4.9 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin KAP_NTPase PF07693.9 OAJ17876.1 - 0.077 11.9 0.1 8.9 5.1 0.0 2.9 3 0 0 3 3 3 0 KAP family P-loop domain Dynamin_N PF00350.18 OAJ17876.1 - 0.12 12.1 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.17 OAJ17876.1 - 0.16 12.1 0.0 6.2 7.0 0.0 3.0 3 0 0 3 3 3 0 RNA helicase PduV-EutP PF10662.4 OAJ17876.1 - 0.17 11.3 1.1 7.6 6.0 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Abhydrolase_6 PF12697.2 OAJ17908.1 - 5.2e-29 101.7 0.1 7.2e-29 101.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ17908.1 - 6.5e-17 61.8 0.0 1.3e-15 57.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ17908.1 - 3.3e-11 43.1 0.0 5.2e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAJ17908.1 - 0.0039 16.6 0.0 0.0053 16.2 0.0 1.3 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 OAJ17908.1 - 0.0055 16.1 0.0 0.14 11.5 0.0 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 OAJ17908.1 - 0.028 14.2 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase FSH1 PF03959.8 OAJ17908.1 - 0.05 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Thioesterase PF00975.15 OAJ17908.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 OAJ17908.1 - 0.14 11.7 0.1 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.13 OAJ17908.1 - 0.16 11.1 0.0 6.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family CybS PF05328.7 OAJ17909.1 - 1.2e-42 144.6 0.0 2e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 CybS DPM2 PF07297.7 OAJ17909.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) START PF01852.14 OAJ17910.1 - 0.0056 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 START domain Ion_trans PF00520.26 OAJ17911.1 - 5.4e-06 25.7 0.1 1e-05 24.8 0.0 1.5 2 0 0 2 2 2 1 Ion transport protein IMS PF00817.15 OAJ17948.1 - 3.1e-28 98.4 0.0 6e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.3 OAJ17948.1 - 0.014 15.4 0.0 0.031 14.3 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif Nuf2 PF03800.9 OAJ17948.1 - 0.26 11.2 0.0 0.54 10.2 0.0 1.4 1 0 0 1 1 1 0 Nuf2 family HSCB_C PF07743.8 OAJ17949.1 - 1.8e-14 53.9 0.7 1.8e-14 53.9 0.5 1.6 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 OAJ17949.1 - 8.4e-10 38.2 0.0 1.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain cwf21 PF08312.7 OAJ17949.1 - 0.0045 16.8 1.4 0.011 15.5 0.9 1.6 1 0 0 1 1 1 1 cwf21 domain EF-hand_1 PF00036.27 OAJ17950.1 - 3.7e-27 91.5 13.3 4.1e-08 31.9 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 OAJ17950.1 - 2.3e-22 78.8 3.8 3.3e-12 46.3 1.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 OAJ17950.1 - 3.7e-20 69.9 8.3 8.6e-05 22.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 OAJ17950.1 - 1.4e-19 68.4 14.2 2.4e-06 26.6 1.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 OAJ17950.1 - 4.1e-15 55.1 15.7 0.00012 21.6 2.0 4.6 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 OAJ17950.1 - 4.1e-05 23.2 6.5 0.0037 16.9 0.6 3.4 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 OAJ17950.1 - 0.00028 20.7 0.1 0.14 12.1 0.1 3.0 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 OAJ17950.1 - 0.00033 20.6 0.0 0.0024 17.8 0.0 2.0 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region VCBS PF13517.1 OAJ17950.1 - 0.017 15.4 1.1 2.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SelR PF01641.13 OAJ17951.1 - 3.2e-50 168.9 0.0 4.3e-50 168.5 0.0 1.2 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.1 OAJ17951.1 - 0.049 13.4 2.2 0.13 12.1 0.2 2.5 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Thymidylat_synt PF00303.14 OAJ17980.1 - 1.3e-27 96.4 0.0 2.3e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Thymidylate synthase AAA_27 PF13514.1 OAJ17980.1 - 0.014 13.0 0.0 0.019 12.7 0.0 1.0 1 0 0 1 1 1 0 AAA domain Cyclin_N PF00134.18 OAJ17981.1 - 3.6e-36 123.5 0.1 8.5e-36 122.3 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ17981.1 - 7.2e-11 42.0 0.5 2.1e-10 40.5 0.4 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF2256 PF10013.4 OAJ18014.1 - 5.3e-12 45.2 4.2 9.9e-12 44.4 2.9 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) Sugar_tr PF00083.19 OAJ18015.1 - 5.6e-34 117.4 23.7 2.8e-33 115.2 16.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ18015.1 - 1.3e-16 60.2 39.4 2.7e-12 46.1 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 OAJ18015.1 - 0.00058 18.6 0.8 0.37 9.4 0.0 2.4 2 0 0 2 2 2 2 BT1 family Baculo_PEP_C PF04513.7 OAJ18016.1 - 4e-05 23.4 11.1 0.0013 18.5 0.3 3.5 2 2 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 OAJ18016.1 - 0.032 13.6 3.0 1.5 8.2 0.2 2.2 2 0 0 2 2 2 0 Intermediate filament protein AAA_13 PF13166.1 OAJ18016.1 - 0.066 11.6 4.1 0.12 10.7 2.3 1.7 1 1 0 1 1 1 0 AAA domain PIN_2 PF10130.4 OAJ18016.1 - 0.15 12.1 1.2 1.6 8.8 0.1 2.5 2 0 0 2 2 2 0 PIN domain Syntaxin PF00804.20 OAJ18016.1 - 0.16 12.1 6.8 0.61 10.2 0.0 3.2 3 1 0 3 3 3 0 Syntaxin Syntaxin-6_N PF09177.6 OAJ18016.1 - 0.29 11.5 4.5 6 7.3 0.7 2.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Sas10_Utp3 PF04000.10 OAJ18016.1 - 0.54 10.4 5.1 0.92 9.7 0.1 3.6 3 1 0 3 3 3 0 Sas10/Utp3/C1D family DUF4407 PF14362.1 OAJ18016.1 - 0.54 9.1 8.2 3.5 6.4 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.8 OAJ18016.1 - 1.3 9.8 4.8 1.3 9.8 1.0 2.3 2 0 0 2 2 2 0 Occludin homology domain Nup54 PF13874.1 OAJ18016.1 - 1.3 8.7 5.6 24 4.5 0.2 3.2 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 Fzo_mitofusin PF04799.8 OAJ18016.1 - 2.2 7.6 6.0 4.4 6.6 1.4 2.4 2 0 0 2 2 2 0 fzo-like conserved region Seryl_tRNA_N PF02403.17 OAJ18016.1 - 3.6 7.6 8.9 7 6.7 0.4 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain WXG100 PF06013.7 OAJ18016.1 - 7 6.7 9.7 20 5.3 0.5 3.7 4 1 0 4 4 4 0 Proteins of 100 residues with WXG Glycoprotein_B PF00606.13 OAJ18017.1 - 0.061 11.3 0.2 0.073 11.1 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B DUF3685 PF12452.3 OAJ18017.1 - 0.097 11.8 0.8 0.18 10.9 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3685) rve PF00665.21 OAJ18062.1 - 5.3e-15 55.5 0.0 2.3e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ18062.1 - 9.7e-07 28.3 0.0 1.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAJ18064.1 - 1.8e-16 60.1 0.0 3.4e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ18064.1 - 3.3e-14 53.0 0.0 8.8e-14 51.6 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.1 OAJ18064.1 - 0.0017 18.1 0.3 0.014 15.1 0.1 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAJ18064.1 - 0.0079 16.6 0.1 0.029 14.8 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 OAJ18100.1 - 4.8e-17 62.0 0.0 8.4e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ18100.1 - 2.8e-13 50.0 0.0 6.3e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ18100.1 - 0.012 16.0 0.0 0.034 14.6 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease RVT_3 PF13456.1 OAJ18138.1 - 0.011 15.4 0.2 0.054 13.2 0.1 2.0 2 0 0 2 2 2 0 Reverse transcriptase-like DNA_pol_viral_C PF00336.13 OAJ18138.1 - 0.045 13.0 0.1 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain Phage_integrase PF00589.17 OAJ18139.1 - 0.0036 16.9 0.0 0.0039 16.8 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family LIP PF03583.9 OAJ18140.1 - 2e-41 142.0 0.2 3e-40 138.2 0.1 2.0 1 1 0 1 1 1 1 Secretory lipase TFIIA PF03153.8 OAJ18176.1 - 0.0034 17.3 0.8 0.0054 16.6 0.5 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RAI16-like PF10257.4 OAJ18178.1 - 4.2e-06 25.9 0.1 4.8e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Nop14 PF04147.7 OAJ18179.1 - 0.0012 16.8 3.6 0.0012 16.8 2.5 1.0 1 0 0 1 1 1 1 Nop14-like family Nucleoplasmin PF03066.10 OAJ18179.1 - 0.011 15.2 10.6 0.018 14.5 7.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 OAJ18179.1 - 0.018 12.9 3.2 0.017 12.9 2.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Prp19_bind PF06991.6 OAJ18179.1 - 0.021 14.1 4.2 0.024 13.9 2.9 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Utp14 PF04615.8 OAJ18179.1 - 0.035 12.2 6.3 0.041 12.0 4.3 1.0 1 0 0 1 1 1 0 Utp14 protein XAP5 PF04921.9 OAJ18179.1 - 0.036 13.6 2.6 0.043 13.3 1.8 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator PBP1_TM PF14812.1 OAJ18179.1 - 0.051 13.8 8.2 0.1 12.9 5.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Daxx PF03344.10 OAJ18179.1 - 0.051 12.0 3.9 0.057 11.8 2.7 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 OAJ18179.1 - 0.053 12.7 5.0 0.057 12.7 3.5 1.1 1 0 0 1 1 1 0 SDA1 eIF-3c_N PF05470.7 OAJ18179.1 - 0.1 10.6 1.5 0.11 10.5 1.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CENP-B_dimeris PF09026.5 OAJ18179.1 - 0.11 12.7 15.2 0.2 11.9 10.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BUD22 PF09073.5 OAJ18179.1 - 0.12 11.4 5.0 0.12 11.3 3.5 1.2 1 0 0 1 1 1 0 BUD22 PI3K_1B_p101 PF10486.4 OAJ18179.1 - 0.16 9.5 3.8 0.18 9.3 2.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RRN3 PF05327.6 OAJ18179.1 - 0.16 10.0 3.2 0.19 9.7 2.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 OAJ18179.1 - 0.17 9.9 3.4 0.18 9.8 2.4 1.2 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 OAJ18179.1 - 0.4 9.7 7.8 0.5 9.4 5.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM176 PF14851.1 OAJ18179.1 - 0.4 10.3 5.4 0.57 9.8 3.8 1.2 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.7 OAJ18179.1 - 0.5 9.5 11.3 0.6 9.3 7.8 1.1 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.13 OAJ18179.1 - 1.1 8.3 6.8 2 7.5 4.7 1.4 1 0 0 1 1 1 0 Myc amino-terminal region DUF2890 PF11081.3 OAJ18179.1 - 1.7 8.7 7.3 2.2 8.3 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Pox_RNA_Pol_19 PF05320.7 OAJ18179.1 - 3.1 7.5 10.2 4.7 6.9 7.0 1.3 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Trypan_PARP PF05887.6 OAJ18179.1 - 4.8 6.9 10.7 5.9 6.7 7.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) S-antigen PF05756.6 OAJ18179.1 - 6 6.9 8.3 10 6.1 5.7 1.3 1 0 0 1 1 1 0 S-antigen protein EBV-NA3 PF05009.7 OAJ18179.1 - 8.4 5.5 7.5 12 5.0 5.2 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) TPR_10 PF13374.1 OAJ18180.1 - 4.4e-07 29.6 10.0 0.015 15.2 0.8 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ18180.1 - 3e-06 27.0 24.9 0.0015 18.4 2.9 6.8 6 1 3 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ18180.1 - 5.8e-05 22.7 10.9 1.3 9.1 1.5 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ18180.1 - 8.2e-05 22.9 14.1 2.2 9.1 0.0 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat Apc3 PF12895.2 OAJ18180.1 - 0.00018 21.5 7.7 5 7.3 0.0 5.3 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 OAJ18180.1 - 0.00031 20.6 0.7 2.6 8.4 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ18180.1 - 0.0007 19.2 4.3 0.91 9.2 0.0 3.7 4 0 0 4 4 2 2 TPR repeat TPR_19 PF14559.1 OAJ18180.1 - 0.0052 17.0 14.6 13 6.2 0.5 6.6 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ18180.1 - 0.01 15.4 8.1 1.4 8.6 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.2 OAJ18180.1 - 0.015 15.1 0.8 0.075 12.8 0.0 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_7 PF13176.1 OAJ18180.1 - 0.027 14.2 7.6 8.5 6.4 0.0 5.4 4 1 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 OAJ18180.1 - 0.051 13.4 2.0 13 5.7 0.0 3.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat YyzF PF14116.1 OAJ18180.1 - 0.08 12.9 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 YyzF-like protein TPR_4 PF07721.9 OAJ18180.1 - 0.14 12.6 13.6 0.19 12.2 0.3 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ18180.1 - 0.22 12.2 15.4 17 6.2 0.0 5.5 5 1 0 5 5 4 0 Tetratricopeptide repeat RNase_PH PF01138.16 OAJ18213.1 - 2.6e-19 69.8 0.0 5.1e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 OAJ18213.1 - 2.1e-05 24.3 0.0 5.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 TPR_11 PF13414.1 OAJ18214.1 - 8e-50 166.3 36.9 4.7e-15 54.9 1.1 6.5 5 1 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 OAJ18214.1 - 4.4e-45 149.5 28.8 2e-05 24.0 0.2 10.1 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ18214.1 - 8.1e-31 103.4 34.1 0.0052 16.6 0.1 10.1 11 0 0 11 11 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ18214.1 - 4.8e-22 78.0 29.9 5.1e-07 30.1 0.6 7.2 4 3 3 7 7 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ18214.1 - 1.2e-21 76.3 28.4 1.3e-11 44.2 0.6 6.2 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ18214.1 - 5.2e-17 60.2 27.1 0.012 15.2 0.1 9.7 8 2 2 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ18214.1 - 5.8e-16 57.5 19.9 0.034 14.7 0.0 9.8 3 3 6 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ18214.1 - 8.7e-10 38.0 11.0 0.036 14.2 0.1 7.9 9 1 0 9 9 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ18214.1 - 1.6e-07 31.5 25.8 1.7e-05 25.0 0.4 6.1 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ18214.1 - 5.2e-07 28.9 17.1 0.036 13.8 0.0 7.4 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ18214.1 - 2.2e-05 24.2 13.3 0.036 13.9 0.6 5.6 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ18214.1 - 2.6e-05 24.3 17.5 2.2 8.9 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ18214.1 - 0.003 17.6 1.4 0.003 17.6 1.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 OAJ18214.1 - 0.034 14.0 3.0 4.7 7.1 0.1 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 OAJ18214.1 - 0.042 13.8 10.8 1.3 9.0 0.2 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3808 PF10300.4 OAJ18214.1 - 0.044 12.3 3.0 0.063 11.8 0.0 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3808) XPC-binding PF09280.6 OAJ18214.1 - 0.13 11.7 4.7 0.29 10.6 1.8 2.6 2 0 0 2 2 2 0 XPC-binding domain Exonuc_VII_S PF02609.11 OAJ18214.1 - 0.22 11.3 5.0 2.7 7.8 0.0 4.9 5 0 0 5 5 5 0 Exonuclease VII small subunit DHHW PF14286.1 OAJ18214.1 - 3.7 6.7 11.8 0.12 11.6 0.3 2.9 2 1 0 3 3 3 0 DHHW protein Ribosomal_S13 PF00416.17 OAJ18215.1 - 1.2e-38 131.8 1.0 1.4e-38 131.6 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.1 OAJ18215.1 - 0.0098 15.9 0.1 0.025 14.6 0.1 1.7 1 1 0 1 1 1 1 Helix-hairpin-helix motif FbpA PF05833.6 OAJ18215.1 - 0.01 14.4 0.0 0.01 14.4 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) WD40 PF00400.27 OAJ18216.1 - 5.7e-20 70.3 1.3 0.00011 21.9 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ARHGEF5_35 PF15441.1 OAJ18216.1 - 0.0035 16.2 0.6 0.0049 15.7 0.4 1.1 1 0 0 1 1 1 1 Rho guanine nucleotide exchange factor 5/35 DEAD PF00270.24 OAJ18249.1 - 2.4e-30 105.2 0.0 5.3e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ18249.1 - 1.3e-20 72.9 0.0 9.7e-12 44.5 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ18249.1 - 9.9e-05 22.2 0.0 9.9e-05 22.2 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 OAJ18249.1 - 0.0065 14.9 0.0 0.49 8.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) RhoGAP PF00620.22 OAJ18250.1 - 2.1e-45 154.0 0.0 3.7e-45 153.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 OAJ18250.1 - 5.5e-17 61.7 0.8 1.9e-16 60.0 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PDEase_II PF02112.10 OAJ18251.1 - 1.1e-39 136.3 0.0 1.5e-20 73.4 0.0 2.2 2 0 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 OAJ18251.1 - 0.00043 19.8 0.0 0.019 14.5 0.0 2.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain SR-25 PF10500.4 OAJ18251.1 - 0.0056 16.1 3.6 0.0056 16.1 2.5 3.3 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein HSP70 PF00012.15 OAJ18291.1 - 2.4e-24 85.2 0.4 2.9e-24 84.9 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein ASF1_hist_chap PF04729.8 OAJ18291.1 - 0.019 14.5 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 ASF1 like histone chaperone MmgE_PrpD PF03972.9 OAJ18292.1 - 1.2e-72 244.5 0.3 4.3e-37 127.3 0.0 2.0 1 1 1 2 2 2 2 MmgE/PrpD family MmgE_PrpD PF03972.9 OAJ18293.1 - 4.1e-12 45.0 0.1 4.7e-12 44.8 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Zeta_toxin PF06414.7 OAJ18337.1 - 0.089 11.8 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Transposase_21 PF02992.9 OAJ18338.1 - 0.0014 17.8 0.1 0.0027 16.8 0.0 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF2457 PF10446.4 OAJ18368.1 - 0.024 13.3 2.6 0.019 13.7 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 OAJ18368.1 - 0.098 10.5 3.0 0.089 10.7 2.1 1.0 1 0 0 1 1 1 0 Nop14-like family AF-4 PF05110.8 OAJ18368.1 - 0.099 10.5 9.0 0.11 10.3 6.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Osteopontin PF00865.13 OAJ18368.1 - 1 8.5 9.7 1.2 8.2 6.7 1.1 1 0 0 1 1 1 0 Osteopontin BUD22 PF09073.5 OAJ18368.1 - 2 7.4 4.0 2 7.4 2.8 1.0 1 0 0 1 1 1 0 BUD22 Myco_19_kDa PF05481.7 OAJ18368.1 - 2.1 8.1 9.8 2.7 7.7 6.8 1.2 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen RNase_H PF00075.19 OAJ18370.1 - 5.3e-06 26.8 0.0 9.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 RNase H Na_Ca_ex PF01699.19 OAJ18403.1 - 8.5e-43 145.3 31.5 2.2e-21 75.9 6.7 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3742 PF12553.3 OAJ18403.1 - 0.53 10.7 2.8 13 6.3 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3742) RNA_pol_Rpb4 PF03874.11 OAJ18404.1 - 5.1e-13 49.0 0.1 7.2e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF1548 PF07579.6 OAJ18404.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) Mito_carr PF00153.22 OAJ18441.1 - 2.6e-28 97.5 2.2 1.6e-14 53.3 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein B12D PF06522.6 OAJ18442.1 - 2.5e-14 52.7 0.0 3e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit GTP_EFTU PF00009.22 OAJ18443.1 - 6.6e-47 159.3 0.1 1.4e-46 158.3 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 OAJ18443.1 - 3.1e-22 78.6 0.1 1.2e-21 76.7 0.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 OAJ18443.1 - 4.3e-08 33.1 0.2 1.6e-07 31.3 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAJ18443.1 - 0.00011 22.1 0.0 0.0003 20.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Med15 PF09606.5 OAJ18443.1 - 0.055 11.6 54.6 0.079 11.1 37.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MSP1_C PF07462.6 OAJ18443.1 - 0.68 8.2 9.7 1.1 7.5 6.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus TFIIA PF03153.8 OAJ18443.1 - 2.8 7.7 33.2 4.7 7.0 23.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit rve PF00665.21 OAJ18472.1 - 7.2e-21 74.5 0.0 4.2e-20 72.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ18472.1 - 1e-15 57.7 0.0 1.9e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ18472.1 - 0.019 15.4 0.0 0.069 13.6 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease rve_3 PF13683.1 OAJ18472.1 - 0.028 13.9 0.0 0.082 12.4 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Myb_DNA-bind_5 PF13873.1 OAJ18511.1 - 0.0085 15.9 0.1 0.029 14.2 0.1 1.9 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Nop14 PF04147.7 OAJ18511.1 - 0.018 13.0 10.4 0.022 12.7 7.2 1.0 1 0 0 1 1 1 0 Nop14-like family Myb_DNA-bind_4 PF13837.1 OAJ18511.1 - 0.055 13.6 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain BUD22 PF09073.5 OAJ18511.1 - 0.1 11.6 5.7 0.11 11.4 3.9 1.1 1 0 0 1 1 1 0 BUD22 FYDLN_acid PF09538.5 OAJ18511.1 - 0.19 12.2 15.7 0.36 11.4 10.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SDA1 PF05285.7 OAJ18511.1 - 2.4 7.3 13.4 3 7.0 9.3 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 OAJ18511.1 - 3.1 5.7 7.1 3.8 5.4 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 OAJ18540.1 - 0.37 11.1 9.3 0.72 10.1 6.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 OAJ18540.1 - 0.4 10.1 5.4 0.18 11.3 1.9 1.8 2 0 0 2 2 2 0 Nucleoplasmin FimP PF09766.4 OAJ18540.1 - 0.89 8.5 5.5 1.4 7.9 3.8 1.2 1 0 0 1 1 1 0 Fms-interacting protein AAA PF00004.24 OAJ18541.1 - 8.9e-34 116.5 0.0 1.4e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ18541.1 - 3.8e-06 27.0 0.2 0.12 12.5 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 OAJ18541.1 - 3.8e-05 23.3 0.2 0.0046 16.6 0.0 3.0 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 OAJ18541.1 - 4e-05 23.6 0.5 0.00017 21.6 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 OAJ18541.1 - 4.6e-05 23.1 0.0 0.00018 21.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 OAJ18541.1 - 0.00053 19.4 1.5 0.046 13.1 0.3 2.4 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ18541.1 - 0.0012 19.6 0.2 0.0064 17.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ18541.1 - 0.0031 17.4 0.1 0.0071 16.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 OAJ18541.1 - 0.0049 16.7 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 OAJ18541.1 - 0.0081 15.7 0.1 0.56 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 OAJ18541.1 - 0.01 15.4 0.0 0.018 14.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAJ18541.1 - 0.037 14.3 1.7 0.26 11.6 0.0 2.5 2 2 0 2 2 2 0 AAA domain AAA_28 PF13521.1 OAJ18541.1 - 0.041 13.8 0.1 0.18 11.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 OAJ18541.1 - 0.093 12.3 0.0 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 OAJ18541.1 - 0.18 11.5 0.6 0.82 9.3 0.0 2.1 2 1 0 2 2 2 0 Archaeal ATPase ANF_receptor PF01094.23 OAJ18541.1 - 0.24 10.1 0.5 12 4.5 0.1 2.1 1 1 1 2 2 2 0 Receptor family ligand binding region Malate_synthase PF01274.17 OAJ18578.1 - 0.011 13.8 0.2 0.074 11.0 0.1 1.9 1 1 0 2 2 2 0 Malate synthase Tyr-DNA_phospho PF06087.7 OAJ18617.1 - 5.3e-38 130.7 0.0 2.5e-21 75.8 0.0 3.3 3 1 0 3 3 3 3 Tyrosyl-DNA phosphodiesterase COX17 PF05051.8 OAJ18618.1 - 0.0056 16.6 3.5 0.14 12.2 0.5 2.5 2 1 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 OAJ18618.1 - 0.0077 15.9 6.1 3.3 7.5 0.9 3.5 1 1 2 3 3 3 2 Cytochrome c oxidase biogenesis protein Cmc1 like YbfN PF13982.1 OAJ18618.1 - 0.017 15.2 0.6 6 7.1 0.0 2.4 2 1 0 2 2 2 0 YbfN-like lipoprotein CHCH PF06747.8 OAJ18618.1 - 0.34 10.8 6.8 5.7 6.9 0.4 3.3 2 2 1 3 3 3 0 CHCH domain UCR_hinge PF02320.11 OAJ18618.1 - 0.38 10.7 4.7 14 5.7 0.1 3.5 2 2 2 4 4 4 0 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 OAJ18618.1 - 0.77 9.8 4.1 4.2 7.4 0.7 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb TPR_12 PF13424.1 OAJ18642.1 - 4.2e-29 100.3 25.1 1.4e-10 40.9 4.2 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ18642.1 - 5.8e-21 73.7 28.6 0.00012 21.8 0.8 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ18642.1 - 4.9e-06 26.0 15.0 0.69 9.9 0.3 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat DUF3856 PF12968.2 OAJ18642.1 - 2.9e-05 23.9 13.5 0.011 15.4 1.1 3.5 2 1 2 4 4 4 3 Domain of Unknown Function (DUF3856) TPR_1 PF00515.23 OAJ18642.1 - 9.7e-05 21.8 2.5 15 5.3 0.1 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ18642.1 - 0.00037 20.0 16.1 0.39 10.3 1.9 4.3 2 2 1 4 4 4 3 TPR repeat PPR PF01535.15 OAJ18642.1 - 0.013 15.3 8.4 66 3.8 0.0 6.9 7 0 0 7 7 7 0 PPR repeat TPR_7 PF13176.1 OAJ18642.1 - 0.026 14.2 20.3 0.32 10.8 0.2 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ18642.1 - 0.058 13.8 8.6 75 4.2 0.0 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF2052 PF09747.4 OAJ18642.1 - 0.088 12.7 0.1 0.088 12.7 0.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) TPR_16 PF13432.1 OAJ18642.1 - 2.5 8.8 22.9 6 7.6 3.0 5.6 4 2 2 6 6 6 0 Tetratricopeptide repeat AP2 PF00847.15 OAJ18642.1 - 2.8 8.1 4.9 40 4.4 0.0 3.1 3 0 0 3 3 3 0 AP2 domain TPR_6 PF13174.1 OAJ18642.1 - 6.2 7.5 10.5 68 4.2 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ18642.1 - 7 7.5 23.4 11 7.0 0.0 7.9 6 2 3 9 9 8 0 Tetratricopeptide repeat rve PF00665.21 OAJ18643.1 - 2.6e-18 66.2 0.0 5.9e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ18643.1 - 0.00028 20.3 0.0 0.00028 20.3 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain DUF2268 PF10026.4 OAJ18643.1 - 0.041 13.2 0.6 0.092 12.1 0.4 1.5 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) HTH_Tnp_4 PF13613.1 OAJ18644.1 - 0.00044 19.7 0.0 0.0011 18.3 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 OAJ18644.1 - 0.002 17.7 0.0 0.0068 16.0 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.2 OAJ18644.1 - 0.0038 16.8 0.0 0.0097 15.5 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.1 OAJ18644.1 - 0.0058 16.3 0.0 0.019 14.7 0.0 1.9 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.17 OAJ18644.1 - 0.01 15.5 0.0 0.032 13.9 0.0 1.8 1 0 0 1 1 1 0 MarR family HTH_28 PF13518.1 OAJ18644.1 - 0.01 15.8 0.2 0.035 14.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain CENP-B_N PF04218.8 OAJ18644.1 - 0.011 15.1 0.0 0.05 13.0 0.0 2.2 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_29 PF13551.1 OAJ18644.1 - 0.031 14.4 0.4 0.089 12.9 0.3 1.8 1 0 0 1 1 1 0 Winged helix-turn helix HTH_38 PF13936.1 OAJ18644.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 OAJ18644.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PPR PF01535.15 OAJ18685.1 - 1.3e-06 28.0 0.0 0.29 11.1 0.0 4.3 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.1 OAJ18685.1 - 3.9e-06 26.7 0.2 0.12 12.7 0.0 4.2 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 OAJ18685.1 - 2.6e-05 24.1 0.0 1.2 9.1 0.0 4.8 4 0 0 4 4 4 1 PPR repeat family PPR_1 PF12854.2 OAJ18685.1 - 0.0019 17.6 0.3 0.033 13.6 0.0 2.4 2 0 0 2 2 2 1 PPR repeat SURF6 PF04935.7 OAJ18729.1 - 1.5e-32 112.6 41.0 1.5e-32 112.6 28.4 3.3 2 2 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 OAJ18729.1 - 1.2e-09 38.0 11.1 1.2e-09 38.0 7.7 5.7 3 2 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 WD40 PF00400.27 OAJ18730.1 - 1.9e-82 268.4 25.5 9.5e-13 47.4 0.0 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 OAJ18730.1 - 1e-05 25.4 0.1 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 OAJ18730.1 - 4.2e-05 23.3 0.0 0.0017 18.1 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 OAJ18730.1 - 0.0011 17.2 6.0 4.7 5.2 0.1 4.7 3 2 0 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAJ18730.1 - 0.0017 17.1 3.5 0.19 10.4 0.1 4.0 3 2 1 4 4 4 1 Nup133 N terminal like Proteasome_A_N PF10584.4 OAJ18730.1 - 0.0018 17.5 1.8 0.2 10.9 0.1 3.0 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Nbas_N PF15492.1 OAJ18730.1 - 0.016 14.3 1.0 0.88 8.6 0.0 2.6 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 OAJ18730.1 - 0.2 9.4 0.1 0.4 8.4 0.0 1.4 1 0 0 1 1 1 0 IKI3 family GreA_GreB_N PF03449.10 OAJ18730.1 - 0.33 11.0 3.7 0.99 9.5 2.6 1.7 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal Beta-lactamase PF00144.19 OAJ18731.1 - 2.9e-37 128.4 0.0 4e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase HMG_box_2 PF09011.5 OAJ18732.1 - 0.033 14.5 0.1 0.12 12.7 0.1 2.0 1 0 0 1 1 1 0 HMG-box domain Trp_syntA PF00290.15 OAJ18766.1 - 3.6e-81 271.5 0.1 7e-81 270.5 0.0 1.5 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 OAJ18766.1 - 2.9e-46 158.1 0.5 6e-46 157.0 0.3 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 OAJ18766.1 - 1.1e-05 24.8 0.1 4e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein PA PF02225.17 OAJ18766.1 - 0.00076 19.1 2.4 0.0052 16.4 0.0 2.6 2 1 0 2 2 2 1 PA domain DFP PF04127.10 OAJ18766.1 - 0.02 14.5 0.1 0.31 10.6 0.1 2.4 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein DUF1631 PF07793.6 OAJ18767.1 - 0.05 11.7 1.7 0.081 11.0 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Arrestin_N PF00339.24 OAJ18801.1 - 9.8e-05 22.2 0.1 0.00051 19.8 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain PAP_central PF04928.12 OAJ18802.1 - 1.2e-92 309.3 0.0 1.6e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 OAJ18802.1 - 1.2e-40 138.6 0.0 2.3e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 OAJ18802.1 - 3.3e-09 36.9 0.0 8.9e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 OAJ18802.1 - 0.049 11.1 0.0 0.07 10.6 0.0 1.1 1 0 0 1 1 1 0 Nrap protein YABBY PF04690.8 OAJ18803.1 - 2.5e-07 31.1 0.9 3.2e-07 30.7 0.6 1.2 1 1 0 1 1 1 1 YABBY protein HMG_box PF00505.14 OAJ18803.1 - 6.4e-05 23.1 0.5 8.4e-05 22.7 0.3 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ18803.1 - 0.017 15.5 0.3 0.023 15.0 0.2 1.2 1 0 0 1 1 1 0 HMG-box domain IER PF05760.7 OAJ18803.1 - 0.21 11.5 1.5 0.22 11.4 1.1 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) RVT_2 PF07727.9 OAJ18847.1 - 2.1e-78 262.7 0.0 2.9e-78 262.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ18847.1 - 6.7e-24 84.3 0.1 3.6e-23 81.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ18847.1 - 6.2e-07 28.9 0.0 8.9e-06 25.2 0.0 2.3 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ18847.1 - 0.054 13.0 0.1 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain UBN2 PF14223.1 OAJ18848.1 - 1.3e-14 53.9 0.1 2.8e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAJ18848.1 - 2.2e-10 40.1 0.0 3.9e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 OAJ18848.1 - 1.4e-08 34.6 0.1 3.5e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAJ18848.1 - 0.31 11.0 2.8 0.58 10.2 2.0 1.5 1 0 0 1 1 1 0 Zinc knuckle NAD_binding_8 PF13450.1 OAJ18849.1 - 1.2e-13 50.8 0.0 2.9e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ18849.1 - 0.00054 18.9 0.1 0.0071 15.2 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAJ18849.1 - 0.043 12.8 0.1 0.069 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 OAJ18849.1 - 0.079 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Chorismate_bind PF00425.13 OAJ18893.1 - 1.1e-73 247.7 0.0 2.8e-73 246.4 0.0 1.7 2 0 0 2 2 2 1 chorismate binding enzyme GATase PF00117.23 OAJ18893.1 - 2.3e-28 98.9 0.0 2e-17 63.3 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 OAJ18893.1 - 3.2e-14 53.1 0.3 1.6e-13 50.8 0.0 2.3 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 OAJ18893.1 - 0.0072 15.7 0.0 0.59 9.5 0.0 2.3 2 0 0 2 2 2 2 Peptidase C26 Tmemb_cc2 PF10267.4 OAJ18894.1 - 0.0062 15.1 6.2 0.0081 14.7 4.3 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Sporozoite_P67 PF05642.6 OAJ18894.1 - 0.13 10.1 9.0 0.18 9.6 6.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.7 OAJ18894.1 - 1.1 8.9 7.4 0.073 12.7 0.5 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Macoilin PF09726.4 OAJ18894.1 - 1.4 7.0 12.5 2.3 6.3 8.7 1.3 1 0 0 1 1 1 0 Transmembrane protein Corona_nucleoca PF00937.13 OAJ18894.1 - 1.7 7.5 10.1 2.5 6.9 7.0 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF2217 PF10265.4 OAJ18894.1 - 1.8 7.2 9.0 2.6 6.7 6.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Sec3_C PF09763.4 OAJ18894.1 - 7.5 4.5 7.3 0.95 7.5 2.3 1.5 2 0 0 2 2 2 0 Exocyst complex component Sec3 Dabb PF07876.7 OAJ18895.1 - 2.8e-19 69.3 0.0 3.2e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Pkinase_Tyr PF07714.12 OAJ18932.1 - 1.5e-08 34.0 0.0 2.6e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 OAJ18932.1 - 4.2e-08 32.6 0.0 3.3e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain F-box PF00646.28 OAJ18968.1 - 1.5e-05 24.4 0.0 9.5e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 F-box domain MFS_1 PF07690.11 OAJ18969.1 - 1.3e-41 142.4 26.5 6.5e-39 133.6 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ18969.1 - 4.7e-14 51.8 7.6 1e-13 50.6 1.6 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 OAJ18969.1 - 0.00031 19.0 3.7 0.00052 18.3 2.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF697 PF05128.7 OAJ18969.1 - 0.0087 15.5 1.6 0.69 9.3 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF697) MCM PF00493.18 OAJ18970.1 - 1.4e-135 451.3 0.2 1.4e-135 451.3 0.2 1.5 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 OAJ18970.1 - 8.5e-19 68.2 0.0 2.5e-18 66.7 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 OAJ18970.1 - 1.1e-07 31.2 0.0 9.1e-07 28.2 0.0 2.2 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 OAJ18970.1 - 0.0015 18.0 0.0 0.0033 16.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ18970.1 - 0.0024 17.6 0.0 0.0066 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 OAJ18970.1 - 0.0026 17.3 0.0 0.0056 16.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SapB_1 PF05184.10 OAJ18970.1 - 0.26 11.1 1.5 1.9 8.4 0.4 2.5 2 0 0 2 2 2 0 Saposin-like type B, region 1 WD40 PF00400.27 OAJ19016.1 - 7e-73 238.1 21.8 2.1e-08 33.7 0.2 12.2 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.7 OAJ19016.1 - 4e-19 68.5 0.2 6.9e-19 67.7 0.2 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 OAJ19016.1 - 8.3e-05 21.5 0.2 2.8 6.5 0.0 4.9 5 1 0 6 6 6 2 Nup133 N terminal like Nbas_N PF15492.1 OAJ19016.1 - 0.0011 18.2 1.3 0.36 9.8 0.0 3.7 4 0 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Pox_Ag35 PF03286.9 OAJ19016.1 - 0.028 13.9 4.2 0.056 12.9 2.9 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sporozoite_P67 PF05642.6 OAJ19016.1 - 0.4 8.4 7.3 0.19 9.5 2.5 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen CDC45 PF02724.9 OAJ19016.1 - 0.51 8.2 5.8 0.95 7.4 4.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 OAJ19016.1 - 9 6.2 9.6 2.2 8.2 4.4 1.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CS PF04969.11 OAJ19017.1 - 1.9e-07 31.5 0.0 2.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 CS domain Serglycin PF04360.7 OAJ19018.1 - 0.0066 16.1 2.7 0.0066 16.1 1.8 2.8 2 1 0 2 2 2 1 Serglycin A_deaminase PF00962.17 OAJ19062.1 - 1.7e-46 158.6 0.0 4.3e-46 157.3 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 OAJ19062.1 - 2.8e-06 27.2 0.0 5.6e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal NOB1_Zn_bind PF08772.6 OAJ19063.1 - 1.3e-27 95.3 2.4 3.5e-27 94.0 1.7 1.7 1 1 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.1 OAJ19063.1 - 1.6 8.0 4.9 3.6 6.9 3.4 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Rad21_Rec8_N PF04825.8 OAJ19064.1 - 1.2e-41 141.1 0.0 2.1e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 OAJ19064.1 - 9.1e-15 53.5 0.1 2.5e-14 52.2 0.1 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 OAJ19064.1 - 4.6e-05 23.1 0.0 0.00061 19.4 0.0 2.2 2 0 0 2 2 2 1 ScpA/B protein FliG_C PF01706.11 OAJ19064.1 - 0.1 12.5 0.6 0.23 11.4 0.4 1.5 1 0 0 1 1 1 0 FliG C-terminal domain Zn_clus PF00172.13 OAJ19128.1 - 2.8e-08 33.5 8.3 4.5e-08 32.8 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAJ19128.1 - 1.9e-06 26.9 0.0 7.4e-06 25.0 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain CENP-X PF09415.5 OAJ19128.1 - 7.5 6.4 5.6 1.8 8.4 0.3 2.5 3 0 0 3 3 3 0 CENP-S associating Centromere protein X HD_3 PF13023.1 OAJ19129.1 - 2.8e-38 131.2 0.0 4.8e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 HD domain HD PF01966.17 OAJ19129.1 - 0.0002 21.3 0.1 0.00051 20.0 0.1 1.7 1 0 0 1 1 1 1 HD domain adh_short PF00106.20 OAJ19171.1 - 4.1e-20 72.3 0.3 6.6e-20 71.6 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ19171.1 - 7.8e-09 35.4 0.5 1.7e-08 34.3 0.3 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ19171.1 - 3.2e-05 23.8 0.7 4.3e-05 23.4 0.1 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase HMG_box PF00505.14 OAJ19172.1 - 8.1e-17 61.2 21.6 5.3e-09 36.2 0.8 3.7 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ19172.1 - 6.7e-16 58.4 14.5 3.5e-10 40.0 0.4 2.8 3 0 0 3 3 3 2 HMG-box domain HMG_box_5 PF14887.1 OAJ19172.1 - 0.0054 16.4 0.2 0.019 14.7 0.1 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box 5 YABBY PF04690.8 OAJ19172.1 - 6.4 6.9 12.7 0.47 10.6 0.1 3.1 3 1 1 4 4 4 0 YABBY protein Sec1 PF00995.18 OAJ19209.1 - 0.01 14.5 0.1 0.012 14.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 OAJ19210.1 - 0.0095 14.6 0.0 0.013 14.1 0.0 1.2 1 1 0 1 1 1 1 Sec1 family FAD_binding_6 PF00970.19 OAJ19254.1 - 1.3e-06 28.4 0.0 8.4e-06 25.8 0.0 2.3 3 0 0 3 3 3 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 OAJ19254.1 - 0.0016 18.9 0.0 0.84 10.2 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain RVT_2 PF07727.9 OAJ19303.1 - 4.8e-71 238.6 0.0 6.7e-71 238.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ19303.1 - 3e-21 75.7 0.0 1e-20 74.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain UBN2 PF14223.1 OAJ19303.1 - 5.8e-08 32.5 0.0 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAJ19303.1 - 5.6e-07 29.1 0.0 9.8e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 OAJ19303.1 - 2.5e-05 23.5 0.2 0.0001 21.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 OAJ19303.1 - 0.0012 18.4 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAJ19303.1 - 0.012 15.1 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain RVP PF00077.15 OAJ19303.1 - 0.017 15.0 0.2 0.14 12.0 0.0 2.5 3 0 0 3 3 3 0 Retroviral aspartyl protease RVT_3 PF13456.1 OAJ19303.1 - 0.049 13.4 0.3 1.1 9.1 0.0 2.9 3 0 0 3 3 3 0 Reverse transcriptase-like GntR PF00392.16 OAJ19303.1 - 0.072 12.5 0.2 1.8 8.0 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family zf-CCHC PF00098.18 OAJ19303.1 - 0.3 11.1 7.4 0.8 9.7 5.1 1.8 1 0 0 1 1 1 0 Zinc knuckle MKT1_C PF12246.3 OAJ19304.1 - 3.8e-64 216.0 0.0 7.3e-63 211.8 0.0 2.5 3 0 0 3 3 3 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 OAJ19304.1 - 2.6e-21 75.7 0.0 5.9e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 OAJ19304.1 - 5.5e-08 32.9 0.0 1.5e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 OAJ19304.1 - 2.6e-05 24.1 0.0 6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region Phostensin_N PF13916.1 OAJ19304.1 - 0.051 13.5 1.1 0.16 11.9 0.8 1.8 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal PB1 PF00564.19 OAJ19305.1 - 5.5e-05 22.7 0.0 9.8e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 PB1 domain Zip PF02535.17 OAJ19305.1 - 0.1 11.6 2.0 0.11 11.5 1.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CBS PF00571.23 OAJ19305.1 - 0.11 12.2 0.4 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 CBS domain SDA1 PF05285.7 OAJ19305.1 - 0.87 8.8 5.8 1.1 8.4 4.0 1.1 1 0 0 1 1 1 0 SDA1 SelP_N PF04592.9 OAJ19305.1 - 3.7 6.8 8.2 4.5 6.5 5.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SMN PF06003.7 OAJ19305.1 - 8.2 5.4 10.5 10 5.1 7.3 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF2340 PF10209.4 OAJ19352.1 - 2.9e-42 143.6 0.0 4e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) RRP7 PF12923.2 OAJ19353.1 - 2.6e-21 76.0 8.2 2.6e-21 76.0 5.7 3.2 2 1 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 OAJ19353.1 - 5.7e-05 22.6 0.0 0.00013 21.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ19353.1 - 0.0018 18.2 0.0 0.004 17.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sec7 PF01369.15 OAJ19354.1 - 6.6e-37 127.0 0.0 1.5e-36 125.8 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 OAJ19354.1 - 1.2e-29 102.8 0.0 2.1e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 OAJ19354.1 - 0.00028 21.0 0.0 0.00055 20.1 0.0 1.4 1 0 0 1 1 1 1 PH domain PhyH PF05721.8 OAJ19355.1 - 1.4e-41 142.8 0.0 2.5e-41 142.0 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pkinase PF00069.20 OAJ19398.1 - 3.7e-72 242.5 0.0 4.5e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ19398.1 - 7.2e-31 107.2 0.0 8.8e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ19398.1 - 0.00055 19.7 0.0 0.00088 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ19398.1 - 0.001 18.2 0.0 0.0031 16.6 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ19398.1 - 0.0039 16.1 0.0 0.029 13.3 0.0 2.0 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 OAJ19398.1 - 0.05 12.9 0.1 0.1 11.9 0.0 1.5 2 0 0 2 2 2 0 RIO1 family DEAD PF00270.24 OAJ19400.1 - 8.8e-13 48.0 0.0 1.3e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DSHCT PF08148.7 OAJ19401.1 - 1.7e-16 60.0 0.1 4.7e-16 58.5 0.1 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.1 OAJ19401.1 - 1.2e-05 24.5 1.9 0.0002 20.6 1.3 2.1 1 1 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 OAJ19401.1 - 0.088 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain H_lectin PF09458.5 OAJ19441.1 - 4.7e-16 58.2 0.0 1.5e-06 27.7 0.0 3.5 3 1 0 3 3 3 3 H-type lectin domain HAD_2 PF13419.1 OAJ19485.1 - 4.9e-11 43.1 0.0 5.2e-08 33.3 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAJ19485.1 - 0.018 14.7 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like COX6B PF02297.12 OAJ19485.1 - 0.083 12.9 0.1 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb DUF2373 PF10180.4 OAJ19486.1 - 2.7e-13 49.2 0.1 1.6e-10 40.3 0.1 2.3 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) NOT2_3_5 PF04153.13 OAJ19486.1 - 0.13 12.1 0.3 0.27 11.1 0.2 1.5 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family CDC45 PF02724.9 OAJ19486.1 - 2.2 6.2 6.0 3.5 5.5 4.1 1.5 1 0 0 1 1 1 0 CDC45-like protein Pro_isomerase PF00160.16 OAJ19487.1 - 7.1e-41 140.0 0.0 1.3e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 OAJ19487.1 - 0.0029 16.8 0.1 0.0029 16.8 0.0 2.7 3 1 0 3 3 3 1 Rtf2 RING-finger AstB PF04996.7 OAJ19487.1 - 2.1 7.0 6.2 0.082 11.7 0.4 1.5 2 0 0 2 2 2 0 Succinylarginine dihydrolase DUF1295 PF06966.7 OAJ19488.1 - 3.5e-35 121.3 0.1 2.4e-34 118.6 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) DnaJ PF00226.26 OAJ19528.1 - 3.7e-14 52.2 0.2 6.8e-14 51.3 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain PDGLE PF13190.1 OAJ19529.1 - 0.043 13.4 2.7 1.3 8.7 0.6 2.5 2 1 0 2 2 2 0 PDGLE domain MoaF PF10703.4 OAJ19529.1 - 0.16 10.9 1.2 0.22 10.5 0.8 1.1 1 0 0 1 1 1 0 Molybdenum cofactor biosynthesis protein F SCHIP-1 PF10148.4 OAJ19529.1 - 0.6 9.4 4.2 0.85 8.9 2.9 1.2 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 Macoilin PF09726.4 OAJ19529.1 - 1.1 7.3 6.1 1.2 7.2 4.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Mucin PF01456.12 OAJ19530.1 - 0.00013 21.7 25.5 0.00013 21.7 17.6 3.3 3 0 0 3 3 3 2 Mucin-like glycoprotein SCIMP PF15050.1 OAJ19530.1 - 0.043 13.6 0.3 0.26 11.1 0.0 2.1 1 1 1 2 2 2 0 SCIMP protein ApbA_C PF08546.6 OAJ19577.1 - 1.1e-23 83.6 0.0 2.9e-23 82.2 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 OAJ19577.1 - 3.7e-19 68.6 0.0 5.8e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.19 OAJ19577.1 - 0.0031 16.4 0.2 0.0065 15.4 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 OAJ19577.1 - 0.0064 16.7 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 OAJ19577.1 - 0.038 13.5 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 OAJ19577.1 - 0.042 13.2 0.2 0.4 10.0 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 OAJ19577.1 - 0.053 13.3 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 ThiF family NAD_binding_10 PF13460.1 OAJ19577.1 - 0.068 13.1 0.0 0.27 11.2 0.0 2.1 3 0 0 3 3 3 0 NADH(P)-binding 3HCDH_N PF02737.13 OAJ19577.1 - 0.11 12.2 0.4 0.43 10.2 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 OAJ19577.1 - 0.13 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 OAJ19577.1 - 0.14 12.6 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.1 OAJ19578.1 - 8.6e-08 32.0 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ19578.1 - 1.3e-07 32.0 0.0 4.4e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ19578.1 - 2.4e-07 31.1 0.0 1.8e-06 28.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ19578.1 - 4.6e-05 23.4 0.0 0.00011 22.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 OAJ19578.1 - 0.00016 22.4 0.1 0.0022 18.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ19578.1 - 0.00073 19.1 0.0 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ19578.1 - 0.0019 18.4 0.0 0.0044 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 OAJ19578.1 - 0.0024 17.2 0.0 0.0086 15.5 0.0 1.8 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.2 OAJ19578.1 - 0.014 15.9 0.0 0.041 14.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ19578.1 - 0.074 12.1 0.0 0.15 11.1 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Chitin_bind_1 PF00187.14 OAJ19579.1 - 0.038 13.9 3.5 0.038 13.9 2.4 2.8 2 1 0 2 2 2 0 Chitin recognition protein MFS_1 PF07690.11 OAJ19580.1 - 8.5e-29 100.3 13.3 8.5e-29 100.3 9.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAJ19580.1 - 2e-09 36.3 4.2 0.0015 17.0 0.0 3.2 2 2 1 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 OAJ19580.1 - 7.6e-07 28.0 8.2 1.4e-06 27.1 4.8 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 OAJ19580.1 - 0.0045 15.2 0.9 0.0069 14.6 0.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 OAJ19580.1 - 0.33 9.3 8.1 0.021 13.3 1.3 2.0 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like Profilin PF00235.14 OAJ19628.1 - 1.3e-39 135.0 0.0 1.4e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Profilin DASH_Dad2 PF08654.5 OAJ19629.1 - 2.8e-21 75.4 0.0 6.5e-21 74.2 0.0 1.6 1 1 0 1 1 1 1 DASH complex subunit Dad2 NDUFA12 PF05071.11 OAJ19630.1 - 3.7e-24 85.1 0.2 4.7e-24 84.8 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PTH2 PF01981.11 OAJ19631.1 - 6.6e-49 164.4 1.1 8.5e-49 164.0 0.8 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Rabaptin PF03528.10 OAJ19631.1 - 0.06 13.2 0.1 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Rabaptin TPR_16 PF13432.1 OAJ19631.1 - 0.43 11.3 0.2 0.43 11.3 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Asp_protease PF09668.5 OAJ19632.1 - 6.3e-60 200.1 0.0 9e-60 199.6 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 OAJ19632.1 - 2e-10 41.0 0.0 5.8e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 OAJ19632.1 - 3.5e-10 39.1 0.0 6.4e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.1 OAJ19632.1 - 6.6e-07 29.0 0.3 3.6e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 OAJ19632.1 - 1.9e-05 24.6 0.0 3.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 OAJ19632.1 - 0.00042 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP PF00077.15 OAJ19632.1 - 0.0007 19.4 0.0 0.0023 17.8 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease Ubiquitin_2 PF14560.1 OAJ19632.1 - 0.0034 17.5 0.0 0.0092 16.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain RabGAP-TBC PF00566.13 OAJ19633.1 - 3e-44 151.0 0.3 6.4e-44 149.9 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SNF2_N PF00176.18 OAJ19678.1 - 3.7e-60 203.2 0.0 5.2e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ19678.1 - 1.7e-13 50.2 0.0 4.4e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ19678.1 - 3.3e-08 33.2 0.0 8.6e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ19678.1 - 9.1e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 OAJ19678.1 - 6.5e-05 21.8 0.0 0.00015 20.6 0.0 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2075 PF09848.4 OAJ19678.1 - 0.056 12.4 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TPR_1 PF00515.23 OAJ19679.1 - 1.6e-28 97.1 11.0 1.6e-05 24.3 0.0 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ19679.1 - 1e-25 87.5 15.8 1.8e-05 24.2 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ19679.1 - 1.4e-25 88.7 13.0 6.8e-09 35.2 0.1 6.4 4 1 2 6 6 6 5 TPR repeat TPR_8 PF13181.1 OAJ19679.1 - 7e-24 81.7 6.5 7.9e-05 22.1 0.0 8.7 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ19679.1 - 6.4e-16 57.4 25.7 0.0027 18.2 0.1 10.3 6 4 5 11 11 9 4 Tetratricopeptide repeat APC8 PF04049.8 OAJ19679.1 - 1.2e-15 57.4 3.1 3.1e-14 52.8 2.2 2.4 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_17 PF13431.1 OAJ19679.1 - 5.9e-15 54.1 6.8 0.00092 19.2 0.0 8.0 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ19679.1 - 1.4e-13 50.5 19.8 0.00025 20.9 0.0 7.7 4 3 4 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 OAJ19679.1 - 7.3e-13 48.4 8.7 0.0063 16.6 0.1 4.6 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 OAJ19679.1 - 1.5e-10 41.4 26.4 0.00074 20.1 0.0 8.2 6 2 2 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ19679.1 - 1.5e-10 40.0 13.3 0.00015 21.3 0.0 6.6 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ19679.1 - 7.3e-10 39.0 9.9 0.019 15.2 0.0 7.3 6 1 0 6 6 6 2 Tetratricopeptide repeat ChAPs PF09295.5 OAJ19679.1 - 6.9e-05 21.7 0.0 0.036 12.8 0.0 3.0 2 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.1 OAJ19679.1 - 0.0003 21.0 17.9 10 6.8 0.0 9.5 10 1 1 11 11 10 0 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ19679.1 - 0.00047 19.9 13.0 1.4 8.8 0.4 5.8 3 1 2 6 6 5 1 Tetratricopeptide repeat RPN7 PF10602.4 OAJ19679.1 - 0.052 12.9 0.7 2.2 7.6 0.1 2.5 2 0 0 2 2 2 0 26S proteasome subunit RPN7 YfiO PF13525.1 OAJ19679.1 - 0.058 12.8 1.5 0.15 11.4 0.0 2.6 4 0 0 4 4 4 0 Outer membrane lipoprotein PPR PF01535.15 OAJ19679.1 - 0.29 11.2 1.8 15 5.8 0.0 3.8 5 0 0 5 5 4 0 PPR repeat PMI_typeI PF01238.16 OAJ19720.1 - 5.7e-110 367.8 0.0 1.8e-109 366.1 0.0 1.7 1 1 0 1 1 1 1 Phosphomannose isomerase type I SSrecog PF03531.9 OAJ19721.1 - 1.2e-73 247.1 0.1 2.4e-72 242.8 0.1 2.1 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 OAJ19721.1 - 3.3e-21 75.0 0.3 7.3e-21 73.9 0.0 1.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CDC45 PF02724.9 OAJ19721.1 - 0.0011 17.0 3.4 0.0016 16.5 2.4 1.1 1 0 0 1 1 1 1 CDC45-like protein Peptidase_M41 PF01434.13 OAJ19760.1 - 5.5e-71 238.4 1.9 6.5e-71 238.1 0.4 1.7 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 OAJ19760.1 - 2.5e-42 144.1 0.0 6.6e-42 142.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 OAJ19760.1 - 2.1e-10 40.7 0.0 7.1e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.1 OAJ19760.1 - 0.00026 21.1 0.0 0.18 11.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 OAJ19760.1 - 0.0045 15.7 0.0 0.007 15.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 OAJ19760.1 - 0.0046 16.3 2.4 0.025 13.9 0.3 2.8 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.1 OAJ19760.1 - 0.0047 16.6 0.2 0.0047 16.6 0.1 2.5 2 0 0 2 2 1 1 Part of AAA domain AAA_5 PF07728.9 OAJ19760.1 - 0.0088 15.7 0.1 0.074 12.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 OAJ19760.1 - 0.0098 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 OAJ19760.1 - 0.013 15.5 0.2 0.13 12.2 0.1 2.5 1 1 1 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 OAJ19760.1 - 0.017 15.9 0.0 0.059 14.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 OAJ19760.1 - 0.02 13.9 0.0 0.047 12.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.7 OAJ19760.1 - 0.067 12.2 1.6 0.069 12.1 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Collagen PF01391.13 OAJ19761.1 - 5.2e-24 83.5 152.3 4.5e-07 29.3 18.1 5.4 1 1 3 4 4 4 3 Collagen triple helix repeat (20 copies) DUF3474 PF11960.3 OAJ19762.1 - 9.1 6.3 10.0 2.4 8.2 1.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3474) Ail_Lom PF06316.6 OAJ19806.1 - 0.033 13.6 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein Alpha_GJ PF03229.8 OAJ19806.1 - 0.056 13.7 2.5 11 6.3 0.0 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J Med3 PF11593.3 OAJ19808.1 - 0.31 10.2 5.1 0.53 9.4 3.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Histone PF00125.19 OAJ19809.1 - 7.9e-28 96.3 0.7 7.8e-27 93.2 0.2 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ19809.1 - 1.5e-05 25.0 0.1 3.1e-05 24.0 0.0 1.5 2 0 0 2 2 2 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAJ19809.1 - 0.0068 16.4 0.4 0.25 11.4 0.0 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 OAJ19809.1 - 0.05 13.3 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated p450 PF00067.17 OAJ19858.1 - 2.5e-49 168.0 0.0 3.3e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3071 PF11268.3 OAJ19858.1 - 0.08 12.6 0.1 0.18 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3071) DDE_1 PF03184.14 OAJ19859.1 - 4.6e-35 120.7 0.0 8.4e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAJ19859.1 - 7.4e-12 44.9 0.2 6.2e-11 41.9 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain Rpn3_C PF08375.6 OAJ19859.1 - 1 9.8 3.9 5.5 7.4 2.7 2.3 1 1 0 1 1 1 0 Proteasome regulatory subunit C-terminal TFIIA PF03153.8 OAJ19860.1 - 0.22 11.3 11.2 0.29 10.9 7.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3474 PF11960.3 OAJ19860.1 - 0.47 10.4 3.2 16 5.5 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) Gag_spuma PF03276.9 OAJ19860.1 - 1.4 7.1 14.8 2.1 6.5 10.2 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Pex14_N PF04695.8 OAJ19860.1 - 1.5 8.8 11.5 2.6 8.1 8.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region p450 PF00067.17 OAJ19861.1 - 1.7e-52 178.5 0.0 2e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4142 PF13628.1 OAJ19861.1 - 0.033 14.2 0.1 0.065 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) CHRD PF07452.7 OAJ19903.1 - 1.8e-16 60.7 0.0 1.7e-07 31.8 0.0 2.9 2 2 0 2 2 2 2 CHRD domain Herpes_UL32 PF06070.6 OAJ19905.1 - 0.0058 15.1 1.5 0.006 15.1 1.0 1.1 1 0 0 1 1 1 1 Herpesvirus large structural phosphoprotein UL32 DUF4611 PF15387.1 OAJ19905.1 - 4.4 7.5 7.4 62 3.8 4.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Acetyltransf_3 PF13302.1 OAJ19906.1 - 9.6e-10 38.7 0.0 1.1e-09 38.6 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ADH_zinc_N PF00107.21 OAJ19945.1 - 1.3e-35 121.7 0.2 2.2e-35 121.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ19945.1 - 1.1e-12 48.9 0.0 2.3e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ19945.1 - 2.7e-06 27.0 0.0 1.1e-05 25.1 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 OAJ19945.1 - 0.018 14.6 0.1 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ribosomal_L4 PF00573.17 OAJ19946.1 - 3.9e-60 202.5 0.0 6.6e-60 201.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Thioredoxin_3 PF13192.1 OAJ19946.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain DUF3591 PF12157.3 OAJ19947.1 - 5.4e-170 565.7 0.1 7e-170 565.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 OAJ19947.1 - 1.4e-05 24.6 3.5 3.5e-05 23.3 2.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 OAJ19947.1 - 0.096 12.6 2.0 0.16 11.9 1.4 1.3 1 0 0 1 1 1 0 Zinc knuckle Mtf2_C PF14061.1 OAJ19991.1 - 0.033 14.0 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 FANCF PF11107.3 OAJ19993.1 - 0.11 11.6 0.0 0.13 11.5 0.0 1.0 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) RVT_1 PF00078.22 OAJ20033.1 - 2.4e-22 79.3 0.0 4.5e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cellulase PF00150.13 OAJ20079.1 - 9.6e-14 51.2 0.5 1.4e-13 50.6 0.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TPR_11 PF13414.1 OAJ20080.1 - 3e-11 42.7 6.2 2.5e-05 23.8 0.1 4.8 3 1 1 4 4 4 3 TPR repeat TPR_16 PF13432.1 OAJ20080.1 - 1.8e-10 41.2 29.4 0.00011 22.7 1.9 6.6 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ20080.1 - 9.4e-10 37.9 0.7 0.014 15.4 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ20080.1 - 2.2e-07 30.2 7.1 0.11 12.4 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ20080.1 - 9e-07 28.9 1.2 0.0087 16.1 0.0 4.5 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 OAJ20080.1 - 5.3e-06 26.5 22.8 0.031 14.8 0.4 7.5 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ20080.1 - 5.1e-05 23.5 17.1 0.14 12.5 0.1 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ20080.1 - 0.0003 20.2 2.7 1.7 8.4 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ20080.1 - 0.0043 16.7 0.1 3.3 7.7 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.5 OAJ20080.1 - 0.056 12.1 1.8 1.5 7.5 0.2 2.5 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.1 OAJ20080.1 - 1.5 8.7 8.3 4.2 7.4 0.0 4.6 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ20080.1 - 1.6 8.6 17.4 1.7 8.5 0.4 5.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ20080.1 - 2 8.3 26.6 0.5 10.3 0.4 6.8 8 1 1 9 9 8 0 Tetratricopeptide repeat RNase_P_Rpp14 PF01900.14 OAJ20081.1 - 2.5e-24 85.2 0.0 3.3e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family TrbC PF04956.8 OAJ20123.1 - 9.4 6.3 14.9 1.1 9.3 0.2 4.4 4 0 0 4 4 4 0 TrbC/VIRB2 family Clp1 PF06807.9 OAJ20124.1 - 2e-05 24.4 0.0 8.6e-05 22.3 0.0 2.0 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 OAJ20124.1 - 0.0073 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 OAJ20124.1 - 0.021 14.8 0.0 0.069 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 OAJ20124.1 - 0.033 13.6 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activat PF00158.21 OAJ20124.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 OAJ20124.1 - 0.098 12.5 0.2 3.1 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 OAJ20124.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAJ20124.1 - 0.21 11.7 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase SH3_1 PF00018.23 OAJ20125.1 - 2e-13 49.4 0.1 3.1e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ20125.1 - 3.8e-10 39.1 0.0 6.5e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ20125.1 - 4e-08 32.6 0.0 7.3e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 OAJ20125.1 - 0.055 13.6 0.5 0.27 11.4 0.1 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain Rib_5-P_isom_A PF06026.9 OAJ20170.1 - 1.6e-54 183.7 0.0 2.5e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 OAJ20170.1 - 0.037 13.6 0.1 0.81 9.3 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain Presenilin PF01080.12 OAJ20171.1 - 0.2 10.4 1.5 0.25 10.1 1.0 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.7 OAJ20171.1 - 7 6.4 9.9 9.6 6.0 6.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cellulase PF00150.13 OAJ20172.1 - 6.9e-12 45.1 0.1 1.5e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Myb_DNA-bind_3 PF12776.2 OAJ20210.1 - 3.2e-16 59.7 2.8 5.4e-16 58.9 1.9 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ20210.1 - 5.9e-07 29.5 3.9 5.9e-07 29.5 2.7 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ20210.1 - 0.0027 17.7 1.7 0.0027 17.7 1.2 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 OAJ20210.1 - 0.017 14.9 3.2 0.017 14.9 2.2 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain YebG PF07130.7 OAJ20210.1 - 0.096 12.3 0.5 0.68 9.6 0.0 2.1 2 0 0 2 2 2 0 YebG protein CENP-B_dimeris PF09026.5 OAJ20210.1 - 0.14 12.3 4.2 0.32 11.2 2.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 OAJ20210.1 - 1.4 8.1 3.4 2 7.5 2.4 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 OAJ20210.1 - 3.3 5.5 6.5 4.1 5.1 4.5 1.2 1 0 0 1 1 1 0 Nop14-like family Spt5_N PF11942.3 OAJ20210.1 - 5.7 7.6 12.3 0.49 11.0 4.4 2.2 2 1 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DNA_pol_phi PF04931.8 OAJ20210.1 - 7.1 4.2 7.2 11 3.6 5.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_60s PF00428.14 OAJ20210.1 - 8.8 6.8 13.0 2.7 8.4 1.5 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein G-alpha PF00503.15 OAJ20211.1 - 7e-134 446.3 1.7 8.5e-134 446.0 1.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 OAJ20211.1 - 7.3e-17 61.1 0.5 7.9e-12 44.7 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ20211.1 - 9.1e-05 21.7 1.0 0.013 14.6 0.0 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 OAJ20211.1 - 0.00056 20.4 0.1 0.78 10.2 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein zf-CHC2 PF01807.15 OAJ20211.1 - 0.0022 17.5 0.0 0.0077 15.7 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger AAA_29 PF13555.1 OAJ20211.1 - 0.0058 16.1 0.2 0.039 13.4 0.1 2.2 1 1 1 2 2 2 1 P-loop containing region of AAA domain MCM PF00493.18 OAJ20211.1 - 0.0094 14.7 0.0 0.02 13.6 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MMR_HSR1 PF01926.18 OAJ20211.1 - 0.013 15.4 0.0 4 7.4 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 OAJ20211.1 - 0.023 14.1 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 OAJ20211.1 - 0.063 12.6 0.0 2.5 7.5 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 OAJ20211.1 - 0.12 12.6 0.0 0.26 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Arm PF00514.18 OAJ20212.1 - 2.6e-74 242.7 9.5 8.8e-12 44.3 0.0 8.5 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 OAJ20212.1 - 2.5e-27 94.9 8.8 5.9e-08 32.8 0.1 6.0 2 1 4 6 6 6 5 HEAT repeats HEAT_EZ PF13513.1 OAJ20212.1 - 7.8e-19 67.5 5.1 2.3e-07 31.0 0.0 5.9 3 3 3 6 6 6 5 HEAT-like repeat HEAT PF02985.17 OAJ20212.1 - 1.7e-15 55.5 1.8 0.0015 18.4 0.0 7.2 7 0 0 7 7 7 3 HEAT repeat IBB PF01749.15 OAJ20212.1 - 5.6e-12 45.6 0.6 1.1e-11 44.7 0.4 1.5 1 0 0 1 1 1 1 Importin beta binding domain RICTOR_V PF14668.1 OAJ20212.1 - 0.00018 21.3 2.2 0.37 10.7 0.0 3.7 3 2 1 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.15 OAJ20212.1 - 0.0011 17.4 0.0 0.0033 15.8 0.0 1.8 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_PBS PF03130.11 OAJ20212.1 - 0.015 15.7 4.3 2.2 9.0 0.0 4.9 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 OAJ20212.1 - 0.24 9.6 0.0 8.7 4.4 0.0 2.3 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit UTP15_C PF09384.5 OAJ20253.1 - 1.8e-36 125.0 0.0 2.9e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 OAJ20253.1 - 1.9e-29 100.4 4.0 3.1e-10 39.5 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF2305 PF10230.4 OAJ20255.1 - 8.8e-47 159.7 0.0 5.9e-46 157.0 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 OAJ20255.1 - 1.6e-08 34.6 1.3 2.9e-08 33.8 0.9 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ20255.1 - 9.8e-06 25.3 0.0 2.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAJ20255.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 OAJ20255.1 - 0.033 13.7 0.1 0.18 11.3 0.1 2.2 3 0 0 3 3 3 0 Serine hydrolase PGAP1 PF07819.8 OAJ20255.1 - 0.043 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 OAJ20255.1 - 0.14 11.7 0.1 0.35 10.4 0.1 1.7 1 1 0 1 1 1 0 Lipase (class 3) DUF3089 PF11288.3 OAJ20255.1 - 0.18 10.9 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) MULE PF10551.4 OAJ20301.1 - 4.2e-17 62.1 0.0 9.1e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ20301.1 - 1.4e-12 46.9 0.0 2.9e-12 45.8 0.0 1.4 2 0 0 2 2 2 1 Transposase, Mutator family FAR1 PF03101.10 OAJ20301.1 - 8.9e-06 26.1 0.3 3e-05 24.4 0.2 1.9 1 0 0 1 1 1 1 FAR1 DNA-binding domain SWIM PF04434.12 OAJ20301.1 - 0.0019 17.6 0.1 0.0043 16.4 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger DDE_Tnp_IS240 PF13610.1 OAJ20301.1 - 0.0023 17.9 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 DDE domain rve PF00665.21 OAJ20301.1 - 0.0038 17.3 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_ISL3 PF01610.12 OAJ20301.1 - 0.0089 15.6 0.1 0.098 12.2 0.0 2.1 1 1 1 2 2 2 1 Transposase PP2C PF00481.16 OAJ20344.1 - 1e-27 97.1 0.0 3.7e-26 92.0 0.0 2.7 2 1 0 2 2 2 1 Protein phosphatase 2C Ribosomal_60s PF00428.14 OAJ20344.1 - 1 9.7 6.6 0.34 11.3 0.7 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein BAF1_ABF1 PF04684.8 OAJ20344.1 - 2.2 7.0 11.1 3.9 6.2 7.7 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor zf-RING_2 PF13639.1 OAJ20345.1 - 9.5e-15 54.1 4.3 2.2e-14 53.0 3.0 1.6 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 OAJ20345.1 - 8.7e-09 34.9 0.0 5.8e-07 29.1 0.0 2.7 2 0 0 2 2 2 1 PA domain zf-C3HC4_2 PF13923.1 OAJ20345.1 - 1.9e-08 34.1 3.4 4e-08 33.1 2.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ20345.1 - 9.5e-06 25.2 2.1 1.8e-05 24.3 1.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 OAJ20345.1 - 1.3e-05 25.2 0.5 2.8e-05 24.1 0.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 OAJ20345.1 - 2.5e-05 23.8 1.7 5.1e-05 22.8 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ20345.1 - 5.6e-05 22.7 5.5 0.00014 21.4 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAJ20345.1 - 0.033 14.0 1.9 0.084 12.7 1.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 OAJ20345.1 - 0.084 12.6 2.7 0.33 10.6 1.2 2.5 2 1 1 3 3 3 0 RING-type zinc-finger zf-Nse PF11789.3 OAJ20345.1 - 0.19 11.2 1.1 0.38 10.3 0.5 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 OAJ20345.1 - 2.4 8.1 4.6 10 6.1 3.1 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain CARD PF00619.16 OAJ20394.1 - 0.18 11.6 0.8 0.28 11.0 0.0 1.6 2 0 0 2 2 2 0 Caspase recruitment domain rve PF00665.21 OAJ20395.1 - 3.8e-22 78.6 0.0 6.1e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 OAJ20395.1 - 4e-06 26.3 0.0 7.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 OAJ20396.1 - 1.5e-08 34.6 0.1 1.1e-07 31.7 0.1 2.2 1 1 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.22 OAJ20397.1 - 4e-24 85.1 0.0 9.3e-24 83.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Daxx PF03344.10 OAJ20442.1 - 0.0022 16.5 9.8 0.003 16.1 6.8 1.1 1 0 0 1 1 1 1 Daxx Family DAHP_synth_2 PF01474.11 OAJ20442.1 - 0.028 12.7 1.0 0.044 12.1 0.7 1.2 1 0 0 1 1 1 0 Class-II DAHP synthetase family CDC45 PF02724.9 OAJ20442.1 - 0.072 11.1 9.0 0.093 10.7 6.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 OAJ20442.1 - 0.62 7.9 20.5 1.1 7.0 14.2 1.3 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.6 OAJ20442.1 - 0.92 9.3 11.6 2.1 8.1 8.1 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) BUD22 PF09073.5 OAJ20442.1 - 1.8 7.5 22.3 0.022 13.8 9.9 1.7 2 0 0 2 2 2 0 BUD22 DUF4656 PF15551.1 OAJ20445.1 - 0.012 14.8 0.3 0.028 13.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4656) COesterase PF00135.23 OAJ20492.1 - 1.9e-110 370.0 0.2 2.5e-110 369.7 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ20492.1 - 3.9e-07 29.8 0.6 5.6e-06 26.0 0.0 2.7 2 2 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_6 PF03737.10 OAJ20493.1 - 2.8e-25 88.9 0.1 1.8e-20 73.3 0.0 2.3 2 0 0 2 2 2 2 Demethylmenaquinone methyltransferase DnaJ PF00226.26 OAJ20493.1 - 1.8e-23 82.0 0.8 3.2e-23 81.2 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 OAJ20493.1 - 2.9e-21 75.1 0.0 1.5e-15 56.8 0.0 2.8 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 OAJ20493.1 - 6.2e-14 51.7 18.6 1.1e-13 51.0 12.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 OAJ20493.1 - 0.069 13.4 6.1 0.14 12.4 4.2 1.6 1 0 0 1 1 1 0 Cytochrome c3 Stc1 PF12898.2 OAJ20493.1 - 0.08 13.0 6.9 0.54 10.3 1.1 2.4 2 0 0 2 2 2 0 Stc1 domain Neisseria_TspB PF05616.8 OAJ20493.1 - 1.3 7.2 5.2 1.9 6.7 3.6 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein NatB_MDM20 PF09797.4 OAJ20494.1 - 3.4e-49 167.5 0.0 5.3e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Exo_endo_phos PF03372.18 OAJ20544.1 - 1.2e-15 58.1 0.1 7e-15 55.6 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sfi1 PF08457.5 OAJ20545.1 - 1.3e-17 63.4 85.2 4.8e-11 41.7 44.4 3.5 1 1 2 3 3 3 3 Sfi1 spindle body protein DUF4366 PF14283.1 OAJ20545.1 - 0.016 14.6 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Ebola_NP PF05505.7 OAJ20545.1 - 3.1 5.7 13.4 4.6 5.1 9.3 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Arm PF00514.18 OAJ20546.1 - 0.00093 18.9 3.1 0.13 12.1 0.1 5.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat DNA_pol_E_B PF04042.11 OAJ20596.1 - 7.3e-29 100.5 0.3 1.1e-28 99.9 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 OAJ20596.1 - 4.4e-18 65.7 0.0 8.9e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal GMC_oxred_N PF00732.14 OAJ20597.1 - 2.9e-51 174.4 1.1 8.5e-50 169.5 0.8 2.3 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ20597.1 - 1.6e-30 106.2 0.0 3.1e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 OAJ20597.1 - 1.7e-06 27.2 0.1 0.0001 21.2 0.0 3.0 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 OAJ20597.1 - 4.4e-06 26.6 0.1 1.1e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAJ20597.1 - 2.4e-05 23.4 0.0 3.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 OAJ20597.1 - 0.00018 20.5 0.1 0.0003 19.8 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAJ20597.1 - 0.012 14.7 0.1 0.023 13.7 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 OAJ20597.1 - 0.013 14.6 0.1 0.029 13.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 OAJ20597.1 - 0.013 15.3 0.1 0.013 15.3 0.1 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ20597.1 - 0.029 14.1 0.2 0.087 12.5 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 OAJ20597.1 - 0.034 12.6 0.1 0.079 11.4 0.1 1.6 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.13 OAJ20597.1 - 0.057 13.4 0.2 0.26 11.3 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain Myb_DNA-bind_3 PF12776.2 OAJ20598.1 - 3.5e-14 53.2 0.3 5.1e-14 52.6 0.2 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain HHH_8 PF14716.1 OAJ20598.1 - 0.007 16.5 0.1 0.012 15.7 0.1 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain Myb_DNA-bind_4 PF13837.1 OAJ20598.1 - 0.041 14.0 0.6 0.041 14.0 0.4 1.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain ORC3_N PF07034.6 OAJ20644.1 - 4.2e-17 62.1 0.1 1.6e-16 60.2 0.1 2.0 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus F-box-like PF12937.2 OAJ20645.1 - 0.00025 20.6 0.3 0.00076 19.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 OAJ20645.1 - 0.029 14.3 2.4 31 5.1 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 OAJ20645.1 - 0.18 12.1 5.6 17 6.2 0.0 4.4 4 0 0 4 4 4 0 Leucine rich repeat LRR_8 PF13855.1 OAJ20645.1 - 2.9 7.7 3.4 22 4.9 0.3 3.2 3 1 0 3 3 3 0 Leucine rich repeat TFIIF_alpha PF05793.7 OAJ20688.1 - 0.83 7.9 11.4 2 6.6 7.9 1.7 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.5 OAJ20688.1 - 1 8.3 10.9 1.8 7.5 7.6 1.3 1 0 0 1 1 1 0 BUD22 DWNN PF08783.6 OAJ20689.1 - 5.4e-31 106.3 0.0 9.7e-31 105.5 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 OAJ20689.1 - 4.5e-06 26.0 3.5 1e-05 24.8 2.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 OAJ20689.1 - 1.7e-05 24.5 2.0 3.3e-05 23.5 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 OAJ20689.1 - 0.00055 19.9 12.0 0.00055 19.9 8.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.1 OAJ20689.1 - 0.002 17.7 0.1 0.0067 16.1 0.1 1.9 1 0 0 1 1 1 1 Zinc knuckle Suf PF05843.9 OAJ20689.1 - 0.44 10.2 3.2 0.82 9.3 2.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-C3HC4_3 PF13920.1 OAJ20689.1 - 5 6.8 13.2 0.75 9.5 6.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CN_hydrolase PF00795.17 OAJ20690.1 - 3.7e-10 39.4 0.0 6.6e-09 35.3 0.0 2.2 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase BUD22 PF09073.5 OAJ20752.1 - 0.11 11.5 11.9 0.13 11.3 8.3 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.7 OAJ20752.1 - 0.16 11.2 11.4 0.17 11.1 7.9 1.1 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 OAJ20752.1 - 0.21 10.0 16.9 0.31 9.4 11.7 1.3 1 0 0 1 1 1 0 Daxx Family RRN3 PF05327.6 OAJ20752.1 - 0.21 9.6 4.2 0.16 10.0 2.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2890 PF11081.3 OAJ20752.1 - 0.27 11.2 10.2 0.3 11.1 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Pox_Ag35 PF03286.9 OAJ20752.1 - 0.48 9.9 8.4 0.95 8.9 5.0 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CDC45 PF02724.9 OAJ20752.1 - 0.49 8.3 11.1 0.52 8.2 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Tom22 PF04281.8 OAJ20752.1 - 0.55 9.7 8.7 0.83 9.1 6.0 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 eIF-3c_N PF05470.7 OAJ20752.1 - 0.66 7.9 3.6 0.55 8.2 2.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF4637 PF15470.1 OAJ20752.1 - 1.6 8.3 8.9 2 8.0 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2457 PF10446.4 OAJ20752.1 - 1.9 7.1 22.0 2.5 6.7 15.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 OAJ20752.1 - 2 6.2 21.9 2.6 5.8 15.1 1.0 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.5 OAJ20752.1 - 2.2 8.2 7.0 2.9 7.8 4.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sigma70_ner PF04546.8 OAJ20752.1 - 2.8 7.5 13.8 4.2 6.9 9.6 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-T PF15511.1 OAJ20752.1 - 3.7 6.6 13.8 4.5 6.4 9.6 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Pox_RNA_Pol_19 PF05320.7 OAJ20752.1 - 4.3 7.0 8.8 7 6.3 6.1 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit TEX19 PF15553.1 OAJ20752.1 - 5.3 6.8 7.7 8.1 6.2 5.3 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 RVT_1 PF00078.22 OAJ20962.1 - 4.9e-16 58.7 0.0 9.8e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NT5C PF06941.7 OAJ20962.1 - 0.05 13.1 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Myb_DNA-bind_3 PF12776.2 OAJ20964.1 - 1.6e-13 51.1 0.6 2.6e-13 50.4 0.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ20964.1 - 0.0037 17.3 2.5 0.011 15.8 1.7 1.9 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.1 OAJ20965.1 - 9.4e-29 100.0 0.0 1.6e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ20965.1 - 3.5e-07 29.8 0.0 0.00021 20.7 0.0 2.5 3 0 0 3 3 3 2 Plant transposon protein DDE_Tnp_1 PF01609.16 OAJ20965.1 - 0.069 12.6 0.1 1.6 8.1 0.0 2.9 2 1 0 2 2 2 0 Transposase DDE domain Herpes_US9 PF06072.6 OAJ20965.1 - 0.57 10.0 2.9 15 5.4 0.1 2.7 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF1793 PF08760.6 OAJ21021.1 - 2.1e-66 222.9 0.8 4.1e-66 222.0 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) zf-CCCH PF00642.19 OAJ21083.1 - 0.18 11.5 10.3 1.6 8.5 2.1 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MFS_1 PF07690.11 OAJ21084.1 - 1.5e-33 115.9 36.8 1.1e-27 96.7 0.2 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Pkinase PF00069.20 OAJ21130.1 - 2.1e-71 240.1 0.0 2.9e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ21130.1 - 8.2e-35 120.1 0.0 1.5e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ21130.1 - 0.00042 19.3 0.0 0.0012 17.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAJ21130.1 - 0.0016 18.2 0.0 0.0069 16.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAJ21130.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 OAJ21130.1 - 0.026 13.5 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Asp PF00026.18 OAJ21131.1 - 1.4e-27 96.8 0.0 2.2e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 OAJ21131.1 - 6.1e-06 26.6 0.1 0.00093 19.6 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease PQ-loop PF04193.9 OAJ21188.1 - 5.1e-20 70.7 18.3 1.7e-10 40.2 0.3 3.3 3 0 0 3 3 3 2 PQ loop repeat Bindin PF02084.10 OAJ21188.1 - 0.0098 15.9 5.6 0.018 15.1 3.9 1.3 1 0 0 1 1 1 1 Bindin DUF21 PF01595.15 OAJ21188.1 - 0.019 14.2 0.2 0.019 14.2 0.1 3.9 4 1 1 5 5 5 0 Domain of unknown function DUF21 DUF3328 PF11807.3 OAJ21188.1 - 0.019 14.6 1.5 6.5 6.3 0.2 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3328) BSP_II PF05432.6 OAJ21188.1 - 0.024 13.9 3.0 0.037 13.3 2.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 OAJ21188.1 - 0.49 10.0 2.9 2.4 7.8 1.1 2.2 2 0 0 2 2 2 0 FAM176 family YrhC PF14143.1 OAJ21188.1 - 1.8 8.6 3.9 3.5 7.6 0.2 2.9 2 0 0 2 2 2 0 YrhC-like protein Daxx PF03344.10 OAJ21188.1 - 4 5.8 7.5 5.4 5.3 5.2 1.1 1 0 0 1 1 1 0 Daxx Family Annexin PF00191.15 OAJ21189.1 - 1.4e-52 175.4 0.2 5e-13 48.7 0.1 4.2 4 0 0 4 4 4 4 Annexin PqqA PF08042.6 OAJ21189.1 - 0.15 11.7 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 PqqA family Peptidase_M43 PF05572.8 OAJ21190.1 - 6.8e-18 64.7 0.1 1e-17 64.1 0.1 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 OAJ21190.1 - 0.0012 18.8 0.4 0.0021 18.0 0.3 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 OAJ21190.1 - 0.0023 17.6 0.1 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.1 OAJ21190.1 - 0.005 17.3 0.1 0.012 16.0 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF2950 PF11453.3 OAJ21190.1 - 0.011 14.7 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) Peptidase_M7 PF02031.11 OAJ21190.1 - 0.025 14.2 0.4 0.056 13.1 0.3 1.7 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_2 PF13574.1 OAJ21190.1 - 0.043 13.8 3.8 0.12 12.4 2.6 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 OAJ21190.1 - 0.18 11.2 1.0 0.29 10.6 0.7 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like LIN37 PF15306.1 OAJ21191.1 - 0.013 15.4 4.6 0.013 15.4 3.2 2.2 2 0 0 2 2 2 0 LIN37 NDK PF00334.14 OAJ21192.1 - 0.00011 21.9 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Pkinase PF00069.20 OAJ21243.1 - 8.2e-53 179.2 0.0 1.1e-29 103.4 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ21243.1 - 8.3e-22 77.4 0.1 1.5e-13 50.4 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ21243.1 - 0.00019 20.5 0.0 0.074 11.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 OAJ21243.1 - 0.002 17.8 0.0 0.0068 16.1 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family YukC PF10140.4 OAJ21243.1 - 0.092 11.3 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC TPR_2 PF07719.12 OAJ21245.1 - 0.013 15.4 3.3 0.072 13.0 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ21245.1 - 0.43 11.3 4.4 29 5.6 0.2 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Apq12 PF12716.2 OAJ21246.1 - 0.21 11.2 2.3 0.52 10.0 1.6 1.6 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Hepatitis_core PF00906.15 OAJ21246.1 - 7.4 6.1 11.8 4 7.0 1.3 2.2 2 0 0 2 2 2 0 Hepatitis core antigen PBP1_TM PF14812.1 OAJ21246.1 - 9.7 6.5 11.7 0.43 10.9 2.6 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDE_1 PF03184.14 OAJ21295.1 - 5.6e-32 110.6 0.0 7e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 OAJ21295.1 - 1.5e-05 24.7 0.1 3.8e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 OAJ21296.1 - 0.01 15.9 0.1 0.031 14.4 0.0 1.7 1 1 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.1 OAJ21296.1 - 0.058 13.4 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 OAJ21296.1 - 0.061 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 ABC2_membrane PF01061.19 OAJ21297.1 - 9.9e-41 139.2 18.9 9.9e-41 139.2 13.1 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 OAJ21297.1 - 4.4e-38 130.6 0.0 1.7e-18 67.2 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 OAJ21297.1 - 1.4e-28 98.5 0.3 6.1e-28 96.5 0.0 2.1 2 0 0 2 2 2 1 CDR ABC transporter ABC_trans_N PF14510.1 OAJ21297.1 - 3.5e-13 49.4 0.1 8.3e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 OAJ21297.1 - 2.9e-07 30.0 0.0 0.00049 19.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 OAJ21297.1 - 1.5e-06 28.3 0.5 4.8e-05 23.4 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain UPF0079 PF02367.12 OAJ21297.1 - 9.9e-06 25.1 0.4 0.013 15.0 0.1 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 OAJ21297.1 - 2e-05 23.8 0.0 8.4e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 OAJ21297.1 - 3.9e-05 23.7 0.3 0.053 13.6 0.1 3.7 2 2 0 2 2 2 1 AAA domain NACHT PF05729.7 OAJ21297.1 - 0.001 18.7 0.0 0.062 12.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain cobW PF02492.14 OAJ21297.1 - 0.001 18.5 0.7 0.012 15.0 0.3 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 OAJ21297.1 - 0.0017 17.8 0.0 0.53 9.7 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 OAJ21297.1 - 0.0037 18.0 0.1 0.071 13.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 OAJ21297.1 - 0.0051 17.1 0.0 0.085 13.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 OAJ21297.1 - 0.012 16.0 0.0 0.68 10.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_19 PF13245.1 OAJ21297.1 - 0.013 15.2 2.3 1.9 8.2 0.1 3.4 3 0 0 3 3 2 0 Part of AAA domain AAA_29 PF13555.1 OAJ21297.1 - 0.013 14.9 0.3 0.13 11.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.1 OAJ21297.1 - 0.014 15.2 0.1 0.24 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 OAJ21297.1 - 0.025 14.5 0.1 0.29 11.1 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.24 OAJ21297.1 - 0.038 14.1 0.3 2 8.6 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 OAJ21297.1 - 0.043 13.7 0.0 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 OAJ21297.1 - 0.15 12.0 0.0 4.1 7.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 OAJ21297.1 - 0.19 11.3 0.4 4.9 6.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 OAJ21297.1 - 0.2 11.1 0.3 0.6 9.5 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC2_membrane PF01061.19 OAJ21298.1 - 3.2e-33 114.6 24.3 3.2e-33 114.6 16.9 1.9 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.7 OAJ21298.1 - 0.02 14.5 0.0 0.059 13.0 0.0 1.8 1 0 0 1 1 1 0 CDR ABC transporter ABC2_membrane_3 PF12698.2 OAJ21298.1 - 4.1 6.3 26.4 0.058 12.4 12.4 2.0 2 1 1 3 3 3 0 ABC-2 family transporter protein DEAD PF00270.24 OAJ21354.1 - 5.2e-49 165.9 0.0 3.3e-47 160.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ21354.1 - 4.4e-27 93.7 0.0 2.1e-26 91.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ21354.1 - 2.3e-05 24.2 0.0 0.00015 21.6 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 OAJ21354.1 - 2.6e-05 23.1 0.0 4.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 OAJ21354.1 - 0.00071 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain AAA_30 PF13604.1 OAJ21354.1 - 0.017 14.6 0.0 0.76 9.3 0.0 3.0 2 1 0 2 2 2 0 AAA domain DUF1253 PF06862.7 OAJ21354.1 - 0.085 11.2 0.0 0.56 8.5 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1253) Glyco_hydro_65m PF03632.10 OAJ21355.1 - 4.6e-76 255.8 2.8 1.6e-75 254.1 0.5 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 OAJ21355.1 - 1.3e-23 83.6 0.0 2.1e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 OAJ21355.1 - 0.0058 16.6 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain DUF2152 PF10222.4 OAJ21355.1 - 0.36 8.9 0.0 24 2.9 0.0 2.7 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2152) p450 PF00067.17 OAJ21356.1 - 2e-65 221.1 0.0 6.7e-50 169.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF1864 PF08933.6 OAJ21356.1 - 0.088 11.3 0.0 0.15 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) OmpH PF03938.9 OAJ21417.1 - 3.5 7.5 10.9 5.4 6.9 7.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Mnd1 PF03962.10 OAJ21417.1 - 6.9 6.2 9.3 10 5.7 6.4 1.3 1 0 0 1 1 1 0 Mnd1 family Presenilin PF01080.12 OAJ21417.1 - 9.6 4.9 5.6 14 4.4 3.9 1.2 1 0 0 1 1 1 0 Presenilin PIF1 PF05970.9 OAJ21418.1 - 1.5e-06 27.4 0.0 5.2e-06 25.6 0.0 1.7 1 1 1 2 2 2 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ21418.1 - 2.8e-06 27.1 0.0 8.3e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Bunya_RdRp PF04196.7 OAJ21418.1 - 0.1 10.6 0.0 0.16 9.9 0.0 1.2 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase MS_channel PF00924.13 OAJ21480.1 - 6.5e-15 55.0 0.5 1.6e-14 53.7 0.4 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 OAJ21480.1 - 0.00016 20.7 0.1 0.00036 19.6 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 OAJ21480.1 - 0.0024 17.5 0.0 0.0076 16.0 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 OAJ21480.1 - 0.009 16.1 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 OAJ21480.1 - 0.016 14.5 0.1 0.036 13.4 0.1 1.6 1 0 0 1 1 1 0 EF hand Zip PF02535.17 OAJ21480.1 - 1.3 7.9 18.8 0.38 9.7 10.2 2.2 1 1 1 2 2 2 0 ZIP Zinc transporter CDK2AP PF09806.4 OAJ21480.1 - 1.7 8.8 12.0 0.51 10.5 4.5 2.3 3 0 0 3 3 3 0 Cyclin-dependent kinase 2-associated protein MS_channel PF00924.13 OAJ21481.1 - 1.1e-22 80.4 0.0 1.6e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 OAJ21481.1 - 0.013 14.8 0.0 0.028 13.7 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 OAJ21481.1 - 0.02 14.7 0.0 0.069 13.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain Orthopox_F8 PF05886.6 OAJ21481.1 - 4.7 7.1 6.5 48 3.8 2.4 2.8 2 0 0 2 2 2 0 Orthopoxvirus F8 protein PHD PF00628.24 OAJ21482.1 - 5.1e-08 32.4 7.2 8.5e-08 31.7 5.0 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 OAJ21482.1 - 2e-06 27.9 0.0 4.7e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD_2 PF13831.1 OAJ21482.1 - 0.02 14.2 1.6 0.035 13.4 1.1 1.5 1 0 0 1 1 1 0 PHD-finger zf-BED PF02892.10 OAJ21536.1 - 0.00045 19.9 2.1 0.00096 18.8 1.4 1.5 1 0 0 1 1 1 1 BED zinc finger IATP PF04568.7 OAJ21538.1 - 0.13 12.3 0.4 0.36 10.8 0.3 1.8 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP LrgB PF04172.11 OAJ21539.1 - 3.7e-11 42.5 0.0 4e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 LrgB-like family PRCC PF10253.4 OAJ21584.1 - 1.5e-06 29.0 20.3 9e-06 26.5 14.1 2.4 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting DAD PF02109.11 OAJ21585.1 - 2.9e-47 159.3 2.9 4e-47 158.9 2.0 1.2 1 0 0 1 1 1 1 DAD family MAGE_N PF12440.3 OAJ21585.1 - 0.021 15.0 20.2 0.04 14.2 14.0 1.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal MDFI PF15316.1 OAJ21585.1 - 0.03 14.2 1.0 0.042 13.8 0.7 1.2 1 0 0 1 1 1 0 MyoD family inhibitor DUF2061 PF09834.4 OAJ21585.1 - 0.041 14.0 0.1 0.094 12.9 0.1 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2061) DUF1180 PF06679.7 OAJ21585.1 - 0.53 10.1 5.0 0.85 9.4 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DNA_pol_viral_N PF00242.12 OAJ21585.1 - 2.5 7.0 5.0 3 6.7 3.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Pex14_N PF04695.8 OAJ21585.1 - 2.5 8.1 10.2 7.1 6.6 7.1 2.0 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Alpha_GJ PF03229.8 OAJ21585.1 - 7.4 6.9 14.5 8.2 6.7 7.5 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J Paf1 PF03985.8 OAJ21586.1 - 3.7e-33 114.9 32.8 4.3e-18 65.2 0.0 4.4 3 1 1 4 4 4 3 Paf1 Pex24p PF06398.6 OAJ21587.1 - 0.00026 19.9 4.2 0.00047 19.0 2.9 1.4 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Adeno_PV PF03910.8 OAJ21587.1 - 0.05 12.6 8.5 0.088 11.8 5.9 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV GCR1_C PF12550.3 OAJ21645.1 - 3.2e-19 68.5 0.4 7.3e-19 67.4 0.3 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Phage_int_SAM_1 PF02899.12 OAJ21645.1 - 0.029 14.5 6.5 11 6.2 0.0 4.7 4 1 1 5 5 5 0 Phage integrase, N-terminal SAM-like domain Xpo1 PF08389.7 OAJ21645.1 - 0.031 14.1 0.2 0.066 13.1 0.1 1.5 1 0 0 1 1 1 0 Exportin 1-like protein Fzo_mitofusin PF04799.8 OAJ21645.1 - 0.08 12.3 1.2 0.17 11.2 0.8 1.5 1 0 0 1 1 1 0 fzo-like conserved region DDE_Tnp_4 PF13359.1 OAJ21646.1 - 0.004 16.7 0.0 0.005 16.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ21646.1 - 0.037 13.4 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein PDT PF00800.13 OAJ21705.1 - 2.6e-42 144.4 0.0 9.7e-36 123.0 0.0 2.9 2 1 0 2 2 2 2 Prephenate dehydratase Pkinase PF00069.20 OAJ21706.1 - 8.6e-37 126.6 0.0 5.1e-11 42.2 0.0 4.2 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ21706.1 - 5e-15 55.2 0.0 3.7e-08 32.7 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase F-box PF00646.28 OAJ21706.1 - 0.026 14.1 2.4 0.072 12.7 1.7 1.7 1 0 0 1 1 1 0 F-box domain ubiquitin PF00240.18 OAJ21707.1 - 1.3e-34 117.3 1.1 1.7e-34 116.9 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 OAJ21707.1 - 1.1e-29 101.7 8.3 1.7e-29 101.1 5.8 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 OAJ21707.1 - 6.4e-20 70.6 0.8 8.5e-20 70.2 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAJ21707.1 - 7.3e-06 26.1 0.2 2.7e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAJ21707.1 - 0.00016 21.3 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 OAJ21707.1 - 0.0077 16.1 0.1 0.015 15.1 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 OAJ21707.1 - 0.011 15.9 0.1 0.014 15.6 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain zf-DHHC PF01529.15 OAJ21707.1 - 0.3 10.4 2.6 0.45 9.8 1.8 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Ribosomal_L18ae PF01775.12 OAJ21708.1 - 2.6e-57 192.0 0.3 3.1e-57 191.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain DUF2883 PF11097.3 OAJ21708.1 - 0.054 13.6 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2883) Transposase_21 PF02992.9 OAJ21765.1 - 0.0015 17.6 0.0 0.0029 16.7 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 ApoC-I PF04691.7 OAJ21766.1 - 0.086 12.5 0.3 17 5.1 0.1 2.7 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) 6PGD PF00393.14 OAJ21831.1 - 1.2e-50 172.3 0.1 1.6e-50 171.9 0.1 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 OAJ21831.1 - 1.4e-14 54.2 0.3 2.1e-14 53.6 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.13 OAJ21831.1 - 3.5e-10 39.6 8.6 5.4e-10 39.0 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_11 PF14833.1 OAJ21831.1 - 0.031 14.3 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Cgr1 PF03879.9 OAJ21832.1 - 5.2e-16 58.7 21.9 5.6e-16 58.6 15.2 1.0 1 0 0 1 1 1 1 Cgr1 family Titin_Z PF09042.6 OAJ21832.1 - 0.055 13.0 0.9 0.055 13.0 0.6 2.4 1 1 1 2 2 2 0 Titin Z PEARLI-4 PF05278.7 OAJ21832.1 - 0.44 9.8 11.2 0.51 9.6 7.8 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Pilt PF15453.1 OAJ21832.1 - 1.4 8.5 7.7 1.6 8.3 5.3 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions DUF4337 PF14235.1 OAJ21832.1 - 10 5.9 9.4 12 5.6 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) MIP PF00230.15 OAJ21833.1 - 4.1e-41 140.9 13.2 5.5e-41 140.5 9.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2160 PF09928.4 OAJ21833.1 - 0.12 12.4 3.0 0.26 11.3 2.1 1.6 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2160) Metallophos PF00149.23 OAJ21834.1 - 6.8e-44 149.6 0.0 1.9e-43 148.2 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Atg14 PF10186.4 OAJ21836.1 - 1.1e-12 47.4 15.5 2.2e-07 30.1 0.0 4.1 2 2 1 3 3 3 2 UV radiation resistance protein and autophagy-related subunit 14 Tat PF00539.13 OAJ21836.1 - 0.18 11.4 1.4 0.36 10.4 0.9 1.4 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) APG6 PF04111.7 OAJ21836.1 - 0.29 10.1 0.9 27 3.6 0.8 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 PAP1 PF08601.5 OAJ21836.1 - 1.6 8.3 4.2 3.6 7.1 2.9 1.5 1 0 0 1 1 1 0 Transcription factor PAP1 COesterase PF00135.23 OAJ21906.1 - 6e-08 31.8 0.0 1e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 OAJ21906.1 - 2.1e-07 30.7 0.1 0.0095 15.6 0.0 3.3 2 1 1 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAJ21906.1 - 5.4e-05 22.8 1.7 0.0011 18.5 0.0 3.1 3 1 1 4 4 4 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAJ21906.1 - 0.00071 18.8 0.0 0.0018 17.5 0.0 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family VirB3 PF05101.8 OAJ21906.1 - 0.08 12.9 1.0 0.18 11.8 0.7 1.5 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Abhydrolase_2 PF02230.11 OAJ21906.1 - 0.082 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase SH3_1 PF00018.23 OAJ21907.1 - 3.5e-39 131.9 8.3 2.1e-16 59.0 0.2 4.5 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 OAJ21907.1 - 4.3e-38 128.6 8.5 5.8e-13 48.1 0.1 4.2 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.7 OAJ21907.1 - 9.5e-28 95.6 0.0 1.8e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.12 OAJ21907.1 - 1.2e-21 75.9 0.0 4.2e-07 29.3 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 OAJ21907.1 - 0.00012 22.1 2.2 0.23 11.6 0.1 3.6 3 0 0 3 3 3 2 Bacterial SH3 domain Lactamase_B_2 PF12706.2 OAJ21908.1 - 1e-17 64.3 0.0 4.7e-17 62.1 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 OAJ21908.1 - 1e-07 31.8 0.0 2.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 OAJ21908.1 - 1.9e-05 24.0 0.0 4.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease PDEase_II PF02112.10 OAJ21908.1 - 0.056 12.3 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II API5 PF05918.6 OAJ21908.1 - 0.11 10.9 2.8 0.15 10.5 1.9 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) EGL-1 PF11430.3 OAJ21908.1 - 0.15 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 Peptidase_C48 PF02902.14 OAJ21968.1 - 5.4e-07 29.4 0.0 9.8e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.4 OAJ21969.1 - 9.4e-10 38.5 0.1 2.5e-08 33.9 0.1 2.5 1 1 0 1 1 1 1 MULE transposase domain E7 PF00527.13 OAJ21969.1 - 0.14 12.3 3.0 9.3 6.4 0.0 3.1 3 0 0 3 3 3 0 E7 protein, Early protein Nop14 PF04147.7 OAJ21969.1 - 0.63 7.8 5.0 0.85 7.4 3.4 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_60s PF00428.14 OAJ21969.1 - 2.5 8.5 10.1 7 7.1 3.9 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein F-box-like PF12937.2 OAJ22027.1 - 0.00062 19.4 0.1 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like LRV PF01816.12 OAJ22028.1 - 0.15 12.2 2.1 0.39 11.0 1.4 1.7 1 0 0 1 1 1 0 Leucine rich repeat variant RVT_1 PF00078.22 OAJ22029.1 - 5.2e-20 71.7 0.0 7e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_4 PF12799.2 OAJ22083.1 - 5.9e-06 25.7 0.0 9.1 6.0 0.0 5.3 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) F-box-like PF12937.2 OAJ22083.1 - 1.1e-05 25.0 3.8 2.4e-05 23.9 1.9 2.3 2 0 0 2 2 2 1 F-box-like CRAL_TRIO PF00650.15 OAJ22084.1 - 8.4e-36 122.8 0.1 1.4e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ22084.1 - 3.5e-13 49.4 0.9 3.5e-13 49.4 0.6 2.3 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DNA_repr_REX1B PF14966.1 OAJ22204.1 - 0.037 14.3 3.8 5.9 7.3 0.1 3.8 3 1 0 3 3 3 0 DNA repair REX1-B Use1 PF09753.4 OAJ22204.1 - 0.21 10.9 5.7 0.27 10.6 1.5 2.0 2 0 0 2 2 2 0 Membrane fusion protein Use1 FliT PF05400.8 OAJ22204.1 - 0.29 11.5 9.2 0.51 10.7 5.8 1.9 1 1 1 2 2 2 0 Flagellar protein FliT SUI1 PF01253.17 OAJ22205.1 - 0.069 12.9 0.2 0.2 11.4 0.1 1.9 1 1 1 2 2 2 0 Translation initiation factor SUI1 Cyt-b5 PF00173.23 OAJ22206.1 - 4.7e-09 35.9 0.1 7.4e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Fungal_trans PF04082.13 OAJ22207.1 - 1.3e-22 79.9 0.0 1.3e-22 79.9 0.0 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ22207.1 - 1.7e-09 37.4 2.4 3.3e-09 36.5 1.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AIP3 PF03915.8 OAJ22362.1 - 1.8e-96 323.6 0.0 3.5e-96 322.6 0.0 1.5 1 1 0 1 1 1 1 Actin interacting protein 3 Syntaxin_2 PF14523.1 OAJ22362.1 - 0.018 15.0 0.4 10 6.2 0.0 3.1 3 0 0 3 3 3 0 Syntaxin-like protein Halo_GVPC PF05465.8 OAJ22362.1 - 0.046 13.6 2.1 1.5 8.8 0.1 2.8 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF2962 PF11176.3 OAJ22363.1 - 3.4e-38 130.6 0.0 4.3e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) HTH_32 PF13565.1 OAJ22363.1 - 0.68 10.7 3.5 0.3 11.9 0.2 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Bud13 PF09736.4 OAJ22364.1 - 5.4e-26 91.5 0.1 7e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex 4HBT_3 PF13622.1 OAJ22365.1 - 4.1e-23 82.4 0.9 4.1e-23 82.4 0.6 2.1 2 1 0 2 2 2 1 Thioesterase-like superfamily Chromate_transp PF02417.10 OAJ22452.1 - 1.9e-54 183.7 31.2 2.6e-29 102.0 7.1 2.9 3 1 0 3 3 3 2 Chromate transporter HEAT_EZ PF13513.1 OAJ22453.1 - 6.7e-06 26.4 5.1 0.0041 17.5 0.2 3.0 1 1 2 3 3 3 3 HEAT-like repeat HEAT_2 PF13646.1 OAJ22453.1 - 0.00024 21.3 3.6 0.061 13.6 0.2 2.5 1 1 2 3 3 3 3 HEAT repeats HEAT PF02985.17 OAJ22453.1 - 0.0012 18.7 8.2 0.0057 16.6 0.1 4.1 4 1 1 5 5 5 1 HEAT repeat DUF1546 PF07571.8 OAJ22453.1 - 0.021 14.9 0.4 0.041 13.9 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1546) DUF2363 PF10155.4 OAJ22453.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2363) MDMPI_N PF11716.3 OAJ22453.1 - 0.45 10.9 3.8 0.65 10.4 2.6 1.3 1 1 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain HEAT_PBS PF03130.11 OAJ22453.1 - 6.9 7.4 7.7 24 5.7 0.4 3.0 2 1 0 2 2 2 0 PBS lyase HEAT-like repeat SAMP PF05924.6 OAJ22453.1 - 8.1 5.7 6.0 14 4.9 0.9 2.5 2 0 0 2 2 2 0 SAMP Motif MFS_1 PF07690.11 OAJ22533.1 - 8.3e-09 34.6 20.7 8.3e-09 34.6 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3526 PF12040.3 OAJ22534.1 - 0.025 14.7 0.1 0.031 14.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) Baculo_PEP_C PF04513.7 OAJ22535.1 - 0.15 11.9 7.7 1.1 9.0 0.9 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_17 PF00332.13 OAJ22536.1 - 5.3e-08 32.2 0.5 0.00057 19.0 0.2 2.4 2 1 0 2 2 2 2 Glycosyl hydrolases family 17 DUF1517 PF07466.6 OAJ22536.1 - 0.71 8.8 3.0 1.2 8.0 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Peptidase_M16 PF00675.15 OAJ22618.1 - 2e-51 173.6 2.8 2.2e-50 170.2 1.3 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 OAJ22618.1 - 5.9e-42 143.4 0.0 5.8e-39 133.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain zf-C3HC4 PF00097.20 OAJ22619.1 - 9.2e-09 34.8 1.3 9.2e-09 34.8 0.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ22619.1 - 2.1e-08 34.0 2.0 2.1e-08 34.0 1.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ22619.1 - 2.2e-07 30.4 1.8 3.1e-05 23.5 0.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ22619.1 - 5.9e-07 29.2 4.7 1.2e-06 28.2 0.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 OAJ22619.1 - 5.3e-05 22.8 1.1 0.00011 21.8 0.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 OAJ22619.1 - 0.00021 21.1 2.6 0.00046 20.0 1.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 OAJ22619.1 - 0.00054 19.6 2.7 0.00054 19.6 1.8 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 OAJ22619.1 - 0.19 11.5 3.8 0.3 10.9 0.8 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-B_box PF00643.19 OAJ22619.1 - 0.72 9.7 2.3 1.4 8.8 1.6 1.4 1 0 0 1 1 1 0 B-box zinc finger zf-rbx1 PF12678.2 OAJ22619.1 - 0.89 9.7 1.0 6.9 6.8 0.2 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger Malate_synthase PF01274.17 OAJ22700.1 - 2.9e-204 678.9 0.0 3.2e-204 678.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase SecE PF00584.15 OAJ22786.1 - 1.2e-13 50.4 0.0 1.3e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Aminotran_1_2 PF00155.16 OAJ22787.1 - 1.6e-20 73.4 0.0 4.7e-20 71.8 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 OAJ22787.1 - 8.5e-05 20.9 0.0 0.00014 20.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3153 PF11353.3 OAJ22787.1 - 0.025 14.0 0.0 0.056 12.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) Pollen_Ole_e_I PF01190.12 OAJ22806.1 - 0.013 15.2 0.1 0.019 14.7 0.1 1.2 1 0 0 1 1 1 0 Pollen proteins Ole e I like PorB PF11565.3 OAJ22806.1 - 0.051 13.7 0.1 0.077 13.2 0.1 1.3 1 0 0 1 1 1 0 Alpha helical Porin B MULE PF10551.4 OAJ22807.1 - 1.3e-08 34.8 0.0 4.6e-08 33.1 0.0 2.0 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 OAJ22807.1 - 0.017 14.5 0.6 0.017 14.5 0.4 2.5 2 0 0 2 2 2 0 SWIM zinc finger DDE_Tnp_IS240 PF13610.1 OAJ22807.1 - 0.075 13.0 0.0 22 5.0 0.0 3.0 3 0 0 3 3 3 0 DDE domain DUF2242 PF10001.4 OAJ22807.1 - 5.5 6.8 6.5 0.35 10.7 0.2 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2242) Carn_acyltransf PF00755.15 OAJ22911.1 - 2.2e-76 257.2 0.0 2.8e-76 256.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CAF-1_p150 PF11600.3 OAJ22912.1 - 0.11 11.8 15.4 0.18 11.1 10.6 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Myb_DNA-bind_4 PF13837.1 OAJ22913.1 - 0.04 14.0 0.1 0.04 14.0 0.1 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Glyco_hydro_47 PF01532.15 OAJ22914.1 - 2.9e-147 490.9 0.0 3.4e-147 490.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TauD PF02668.11 OAJ22915.1 - 2.5e-47 161.7 1.7 3.1e-47 161.4 1.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 OAJ22915.1 - 0.063 13.7 0.3 0.77 10.3 0.1 2.5 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily zf-CCHC_4 PF14392.1 OAJ22932.1 - 2.9 7.6 7.0 1 9.0 0.8 2.3 2 0 0 2 2 2 0 Zinc knuckle Dimer_Tnp_hAT PF05699.9 OAJ22933.1 - 8.3e-15 54.1 0.4 1.7e-14 53.1 0.3 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAJ22933.1 - 5.7e-07 29.4 0.2 7.6e-06 25.8 0.0 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF4413) Pkinase PF00069.20 OAJ22934.1 - 5.3e-20 71.6 0.1 1.1e-19 70.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ22934.1 - 7.2e-13 48.1 0.0 9.5e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ22934.1 - 3.3e-05 22.9 0.1 5.5e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Kinase-like DNA_pol_viral_C PF00336.13 OAJ22935.1 - 0.032 13.4 0.0 0.071 12.3 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain RVT_3 PF13456.1 OAJ22935.1 - 0.098 12.4 0.1 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase-like Rac1 PF09632.5 OAJ22936.1 - 0.071 12.1 0.0 0.087 11.8 0.0 1.1 1 0 0 1 1 1 0 Rac1-binding domain MULE PF10551.4 OAJ22955.1 - 4.5e-18 65.2 0.0 1e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ22955.1 - 3.9e-14 52.0 0.1 7.9e-14 50.9 0.0 1.5 2 0 0 2 2 2 1 Transposase, Mutator family SWIM PF04434.12 OAJ22955.1 - 6.4e-06 25.5 0.4 1.5e-05 24.3 0.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger DDE_Tnp_IS240 PF13610.1 OAJ22955.1 - 0.00027 20.9 0.0 0.00069 19.5 0.0 1.6 1 0 0 1 1 1 1 DDE domain rve PF00665.21 OAJ22955.1 - 0.011 15.8 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain DDE_Tnp_ISL3 PF01610.12 OAJ22955.1 - 0.05 13.1 0.0 0.14 11.7 0.0 1.7 1 1 1 2 2 2 0 Transposase HA2 PF04408.18 OAJ22973.1 - 7.7e-19 67.6 0.1 2.6e-18 65.9 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ22973.1 - 5.7e-13 48.5 0.2 1.4e-12 47.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 OAJ22973.1 - 1.8e-09 37.3 0.0 4.5e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 OAJ22973.1 - 4.4e-09 36.0 0.0 9e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ22973.1 - 1.9e-07 31.2 0.2 1.1e-06 28.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 OAJ22973.1 - 0.012 14.5 0.0 0.027 13.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 OAJ22973.1 - 0.021 14.5 0.0 0.099 12.4 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_29 PF13555.1 OAJ22973.1 - 0.03 13.8 0.0 0.084 12.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 OAJ22973.1 - 0.049 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 KaiC Arch_ATPase PF01637.13 OAJ22973.1 - 0.13 11.9 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase AAA_23 PF13476.1 OAJ22973.1 - 0.23 11.7 0.1 0.79 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Abhydrolase_5 PF12695.2 OAJ22974.1 - 0.039 13.6 0.0 0.093 12.4 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ22974.1 - 0.051 13.4 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2613 PF11021.3 OAJ22990.1 - 0.95 9.2 4.3 0.29 10.8 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Fork_head PF00250.13 OAJ22991.1 - 2.3e-21 75.6 0.0 4.6e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Fork head domain tRNA-synt_2d PF01409.15 OAJ22992.1 - 7.4e-87 290.6 0.0 1e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 OAJ22992.1 - 4.9e-06 26.2 0.0 8.9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 OAJ22992.1 - 4.8e-05 22.3 1.1 0.0012 17.6 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) GRP PF07172.6 OAJ23012.1 - 2.8 8.4 12.5 1.9 9.0 7.7 1.4 1 1 0 1 1 1 0 Glycine rich protein family Aldo_ket_red PF00248.16 OAJ23013.1 - 2.5e-42 144.6 0.0 3e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HxlR PF01638.12 OAJ23013.1 - 0.078 12.6 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 HxlR-like helix-turn-helix NUP PF06516.6 OAJ23014.1 - 2.2e-113 378.2 0.1 2.7e-113 377.9 0.1 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) zf-C3HC4_2 PF13923.1 OAJ23015.1 - 1.8e-08 34.2 3.0 1.8e-08 34.2 2.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ23015.1 - 5.4e-08 32.5 1.7 6.5e-07 29.0 0.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 OAJ23015.1 - 1.3e-07 31.1 1.2 1.3e-07 31.1 0.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ23015.1 - 2.3e-05 23.9 3.2 0.00024 20.7 0.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ23015.1 - 0.0002 21.0 1.8 0.0002 21.0 1.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 OAJ23015.1 - 0.00086 19.1 3.9 0.00086 19.1 2.7 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 OAJ23015.1 - 0.0034 17.0 0.9 0.0034 17.0 0.7 1.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-dskA_traR PF01258.12 OAJ23015.1 - 0.049 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger zf-Nse PF11789.3 OAJ23015.1 - 0.088 12.3 0.3 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Hid1 PF12722.2 OAJ23015.1 - 4.9 4.7 3.6 7.4 4.1 2.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Methyltransf_23 PF13489.1 OAJ23016.1 - 0.00019 21.1 0.0 0.0016 18.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Rhodanese PF00581.15 OAJ23016.1 - 0.0036 17.6 0.0 0.0067 16.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain TehB PF03848.9 OAJ23016.1 - 0.19 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB AA_permease_2 PF13520.1 OAJ23035.1 - 6.7e-55 186.3 50.5 8.3e-55 186.0 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAJ23035.1 - 7e-12 44.4 50.1 1.6e-11 43.2 34.8 1.5 1 1 0 1 1 1 1 Amino acid permease HIG_1_N PF04588.8 OAJ23036.1 - 2.8e-05 23.7 1.5 7e-05 22.4 1.1 1.7 1 0 0 1 1 1 1 Hypoxia induced protein conserved region ENOD93 PF03386.9 OAJ23036.1 - 0.005 16.5 0.3 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 Early nodulin 93 ENOD93 protein Opi1 PF08618.5 OAJ23037.1 - 5.1e-69 233.2 5.6 5.1e-69 233.2 3.9 4.2 4 1 0 5 5 5 1 Transcription factor Opi1 Glyco_hydro_2 PF00703.16 OAJ23054.1 - 9.6e-09 35.6 0.1 2e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 OAJ23054.1 - 0.06 12.2 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Membr_traf_MHD PF10540.4 OAJ23055.1 - 3.4e-15 56.0 0.0 1e-14 54.5 0.0 1.8 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 OAJ23055.1 - 0.00035 20.3 0.0 0.00074 19.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain SSXT PF05030.7 OAJ23056.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 SSXT protein (N-terminal region) Pkinase PF00069.20 OAJ23078.1 - 2.3e-40 138.4 0.0 1e-29 103.5 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ23078.1 - 6.6e-23 81.1 0.0 4.6e-16 58.6 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 OAJ23078.1 - 0.015 15.0 4.2 0.037 13.7 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Serglycin PF04360.7 OAJ23078.1 - 0.089 12.5 8.7 0.28 10.8 6.1 1.8 1 0 0 1 1 1 0 Serglycin Kinase-like PF14531.1 OAJ23078.1 - 0.11 11.4 0.0 0.81 8.5 0.0 1.9 2 0 0 2 2 2 0 Kinase-like LSM PF01423.17 OAJ23079.1 - 1.7e-13 49.9 0.0 2.6e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 OAJ23079.1 - 7.4e-05 22.5 0.0 9.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2642 PF10842.3 OAJ23079.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) Sds3 PF08598.6 OAJ23098.1 - 1.3e-22 80.3 5.2 1.3e-22 80.3 3.6 1.9 2 1 0 2 2 2 1 Sds3-like Y_phosphatase2 PF03162.8 OAJ23099.1 - 5e-31 107.2 0.0 1.1e-23 83.4 0.0 3.1 3 0 0 3 3 3 3 Tyrosine phosphatase family CoA_trans PF01144.18 OAJ23100.1 - 7.8e-106 352.1 0.3 1.4e-63 213.9 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 OAJ23100.1 - 0.13 11.9 0.1 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Involucrin_N PF10583.4 OAJ23100.1 - 0.2 12.0 0.5 0.38 11.1 0.3 1.5 1 0 0 1 1 1 0 Involucrin of squamous epithelia N-terminus B56 PF01603.15 OAJ23110.1 - 4.2e-169 562.4 3.0 5e-169 562.2 2.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Hat1_N PF10394.4 OAJ23111.1 - 4e-35 121.2 0.0 8.7e-35 120.1 0.0 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 OAJ23111.1 - 0.001 19.1 0.0 0.0031 17.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAJ23111.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAJ23111.1 - 0.09 12.8 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MOZ_SAS PF01853.13 OAJ23111.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 MOZ/SAS family Phage_integrase PF00589.17 OAJ23125.1 - 3.4e-05 23.6 0.2 0.00011 21.8 0.0 2.0 3 0 0 3 3 3 1 Phage integrase family RVT_3 PF13456.1 OAJ23125.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like DUF2778 PF10908.3 OAJ23125.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2778) MIP-T3 PF10243.4 OAJ23126.1 - 1.4 7.2 50.0 0.94 7.8 24.6 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 GCR1_C PF12550.3 OAJ23127.1 - 7.7e-19 67.3 1.0 1.4e-18 66.5 0.7 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Leo1 PF04004.8 OAJ23127.1 - 0.31 10.7 3.9 0.26 10.9 0.2 2.2 2 0 0 2 2 2 0 Leo1-like protein Cellulase PF00150.13 OAJ23147.1 - 0.002 17.4 0.0 0.0022 17.2 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Fork_head PF00250.13 OAJ23148.1 - 3.9e-11 42.8 0.0 1.4e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Fork head domain Phostensin_N PF13916.1 OAJ23148.1 - 0.6 10.1 15.2 0.55 10.2 1.9 3.1 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal FimP PF09766.4 OAJ23148.1 - 3 6.8 15.4 0.6 9.1 3.2 2.1 2 0 0 2 2 2 0 Fms-interacting protein Spt20 PF12090.3 OAJ23148.1 - 9.5 5.5 12.3 8.8 5.6 0.8 2.2 2 0 0 2 2 2 0 Spt20 family SWIM PF04434.12 OAJ23169.1 - 0.00026 20.3 0.1 0.00058 19.2 0.0 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-BED PF02892.10 OAJ23170.1 - 0.055 13.2 0.3 0.086 12.6 0.2 1.3 1 0 0 1 1 1 0 BED zinc finger FAR1 PF03101.10 OAJ23172.1 - 0.0038 17.6 0.2 0.0062 17.0 0.1 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain ALS2CR8 PF15299.1 OAJ23172.1 - 0.046 13.3 1.0 4.3 6.8 0.0 2.2 1 1 1 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Aldedh PF00171.17 OAJ23173.1 - 1.7e-11 43.1 0.1 2.3e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1325 PF07039.6 OAJ23173.1 - 8.6e-10 38.3 0.0 1.2e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain PGM_PMM_I PF02878.11 OAJ23173.1 - 0.0019 17.6 0.0 0.0035 16.8 0.0 1.5 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Aldedh PF00171.17 OAJ23174.1 - 7.4e-22 77.3 0.0 8.4e-22 77.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family cNMP_binding PF00027.24 OAJ23192.1 - 9.1e-13 47.8 0.0 1.9e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Sulfate_transp PF00916.15 OAJ23192.1 - 4e-12 45.7 0.2 7.2e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 OAJ23192.1 - 1.9e-10 40.1 0.1 4.2e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 STAS domain DUF1985 PF09331.6 OAJ23192.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) TM_helix PF05552.7 OAJ23192.1 - 8.2 6.1 8.5 0.7 9.6 1.0 2.5 2 0 0 2 2 2 0 Conserved TM helix Sulfate_transp PF00916.15 OAJ23193.1 - 3.8e-06 26.1 0.2 7.2e-06 25.2 0.2 1.4 1 0 0 1 1 1 1 Sulfate transporter family SAM_2 PF07647.12 OAJ23209.1 - 0.00052 19.8 0.0 0.00087 19.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) KilA-N PF04383.8 OAJ23209.1 - 0.00077 19.0 0.0 1.4 8.5 0.0 2.3 1 1 1 2 2 2 2 KilA-N domain WD40 PF00400.27 OAJ23210.1 - 1.6e-19 69.0 11.9 2.9e-07 30.0 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Es2 PF09751.4 OAJ23211.1 - 1.3e-63 215.8 3.4 4.1e-63 214.2 2.3 1.9 1 1 0 1 1 1 1 Nuclear protein Es2 QRPTase_C PF01729.14 OAJ23212.1 - 3e-42 144.0 0.4 2.4e-40 137.8 0.2 2.1 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 OAJ23212.1 - 6.1e-21 74.0 0.0 1.6e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribosomal_60s PF00428.14 OAJ23213.1 - 1.1 9.7 6.2 1.5 9.2 4.3 1.3 1 1 0 1 1 1 0 60s Acidic ribosomal protein E2_bind PF08825.5 OAJ23232.1 - 0.076 12.7 0.6 0.13 12.0 0.4 1.4 1 0 0 1 1 1 0 E2 binding domain TBPIP PF07106.8 OAJ23232.1 - 0.2 11.1 1.8 1.7 8.1 0.8 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Zn_clus PF00172.13 OAJ23234.1 - 2.8e-05 23.9 8.0 4.9e-05 23.1 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PITH PF06201.8 OAJ23235.1 - 3.6e-21 75.5 0.0 1.4e-15 57.3 0.0 2.1 2 0 0 2 2 2 2 PITH domain MTHFR PF02219.12 OAJ23273.1 - 1.5e-110 368.8 0.0 2e-110 368.4 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Cyt-b5 PF00173.23 OAJ23292.1 - 2.8e-13 49.4 0.0 4.2e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain LETM1 PF07766.8 OAJ23293.1 - 1.9e-95 318.9 1.6 1.9e-95 318.9 1.1 2.2 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.1 OAJ23293.1 - 0.00015 21.8 0.4 0.0017 18.4 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.1 OAJ23293.1 - 0.0028 17.2 0.2 0.011 15.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 OAJ23293.1 - 0.015 14.5 2.2 1.9 8.0 0.0 3.4 4 0 0 4 4 4 0 EF hand EF-hand_6 PF13405.1 OAJ23293.1 - 0.059 13.2 3.3 7.6 6.7 0.0 4.0 4 0 0 4 4 4 0 EF-hand domain Neur_chan_memb PF02932.11 OAJ23293.1 - 0.72 9.6 2.7 4.3 7.1 0.7 2.3 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Rot1 PF10681.4 OAJ23294.1 - 1.5e-60 204.1 1.4 2.3e-60 203.5 1.0 1.2 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal NAD_synthase PF02540.12 OAJ23295.1 - 1.9e-23 82.6 0.0 2.2e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 NAD synthase CN_hydrolase PF00795.17 OAJ23295.1 - 1.8e-12 46.9 0.0 3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.16 OAJ23295.1 - 0.11 11.9 0.0 0.29 10.5 0.0 1.6 1 1 0 1 1 1 0 Asparagine synthase DSBA PF01323.15 OAJ23308.1 - 2.9e-25 88.9 0.0 3.7e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Aldo_ket_red PF00248.16 OAJ23310.1 - 3.5e-52 176.9 0.0 4.2e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RNA_pol_I_A49 PF06870.7 OAJ23332.1 - 3.3e-61 206.9 0.0 1.3e-60 205.0 0.0 1.7 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor Methyltransf_23 PF13489.1 OAJ23332.1 - 8.9e-14 51.5 0.0 2.1e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ23332.1 - 5.9e-09 36.3 0.0 1.3e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ23332.1 - 6.1e-08 33.0 0.0 1.4e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ23332.1 - 3.3e-05 24.4 0.0 8.9e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ23332.1 - 0.0011 18.5 0.0 0.0023 17.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 OAJ23332.1 - 0.0014 17.3 0.0 0.0023 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 OAJ23332.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Asp PF00026.18 OAJ23344.1 - 3e-47 161.4 0.0 3.4e-29 102.0 0.1 3.5 3 1 0 3 3 3 3 Eukaryotic aspartyl protease TAXi_C PF14541.1 OAJ23344.1 - 0.00026 20.5 0.3 0.021 14.3 0.1 3.1 3 1 0 3 3 3 1 Xylanase inhibitor C-terminal DUF2781 PF10914.3 OAJ23345.1 - 3.7e-30 104.6 7.7 4.4e-30 104.4 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Zn_clus PF00172.13 OAJ23346.1 - 1.3e-06 28.2 9.6 2.2e-06 27.4 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.21 OAJ23360.1 - 6.8e-07 28.7 0.0 6.1e-05 22.3 0.0 2.0 1 1 0 1 1 1 1 Proteasome subunit CHCH PF06747.8 OAJ23361.1 - 3.1e-05 23.7 4.9 3.1e-05 23.7 3.4 2.5 2 1 0 2 2 2 1 CHCH domain Pet191_N PF10203.4 OAJ23361.1 - 0.33 11.0 9.7 0.37 10.8 2.9 2.7 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 DUF3128 PF11326.3 OAJ23361.1 - 1.1 9.4 5.9 0.38 10.9 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) FAD-oxidase_C PF02913.14 OAJ23362.1 - 1.4e-58 198.1 0.0 2.2e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 OAJ23362.1 - 1.4e-33 115.2 1.0 2.8e-33 114.3 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain SMP_2 PF10144.4 OAJ23362.1 - 0.087 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin Relaxase PF03432.9 OAJ23362.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Ilar_coat PF01787.11 OAJ23362.1 - 0.19 11.3 0.6 0.69 9.4 0.0 2.1 2 1 0 2 2 2 0 Ilarvirus coat protein EpuA PF11772.3 OAJ23362.1 - 0.34 10.3 1.8 1.1 8.7 1.3 1.9 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta MMR_HSR1 PF01926.18 OAJ23363.1 - 9.7e-17 60.9 0.0 1.1e-14 54.4 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ23363.1 - 5.8e-06 25.6 0.0 6e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 OAJ23363.1 - 8e-05 21.8 0.0 0.00016 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 OAJ23363.1 - 0.0014 17.8 0.0 0.0046 16.1 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 OAJ23363.1 - 0.095 13.2 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein SAPS PF04499.10 OAJ23363.1 - 0.15 10.6 3.5 0.22 10.1 2.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HTH_17 PF12728.2 OAJ23363.1 - 0.18 12.0 0.8 12 6.2 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain Nop14 PF04147.7 OAJ23363.1 - 0.2 9.5 21.4 0.27 9.1 14.8 1.1 1 0 0 1 1 1 0 Nop14-like family Dynamin_N PF00350.18 OAJ23363.1 - 0.3 10.8 7.0 0.12 12.2 0.5 2.8 3 1 1 4 4 4 0 Dynamin family SDA1 PF05285.7 OAJ23363.1 - 0.34 10.1 21.6 0.53 9.5 15.0 1.2 1 0 0 1 1 1 0 SDA1 RNA_pol_3_Rpc31 PF11705.3 OAJ23363.1 - 1.4 8.7 21.1 3 7.7 14.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Spore_coat_CotO PF14153.1 OAJ23363.1 - 1.7 8.0 9.8 0.3 10.5 4.2 1.6 2 0 0 2 2 2 0 Spore coat protein CotO MscS_TM PF12794.2 OAJ23363.1 - 3.5 6.1 3.5 5.4 5.5 2.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Ribosomal_60s PF00428.14 OAJ23363.1 - 3.7 8.0 17.5 11 6.5 12.1 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein NOA36 PF06524.7 OAJ23363.1 - 5.4 6.1 14.5 8.7 5.5 10.1 1.3 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 OAJ23363.1 - 5.7 5.2 25.6 8.5 4.7 17.7 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 OAJ23363.1 - 7.6 4.4 16.9 11 3.9 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA PF00004.24 OAJ23364.1 - 1.2e-90 300.5 0.0 3.5e-46 156.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 OAJ23364.1 - 6.2e-14 51.6 0.0 9.3e-07 28.1 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 OAJ23364.1 - 9.9e-12 45.1 0.2 0.0032 17.6 0.0 4.9 3 2 1 4 4 3 3 AAA domain AAA_17 PF13207.1 OAJ23364.1 - 4e-11 43.7 0.0 8e-06 26.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.9 OAJ23364.1 - 7.9e-11 42.1 0.0 0.00022 21.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 OAJ23364.1 - 1.4e-10 41.0 0.3 0.0014 18.3 0.1 4.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 OAJ23364.1 - 1.6e-10 41.2 6.0 0.00041 20.3 0.1 4.3 3 1 0 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 OAJ23364.1 - 1.5e-09 37.0 0.0 1.8e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 OAJ23364.1 - 6.3e-09 35.8 0.0 0.0044 16.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.1 OAJ23364.1 - 7.8e-09 35.5 0.0 0.0045 16.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 OAJ23364.1 - 9e-08 31.4 0.0 0.013 14.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 OAJ23364.1 - 1.7e-07 30.8 0.0 0.013 14.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.7 OAJ23364.1 - 4e-07 29.8 0.7 0.034 13.8 0.1 4.0 3 1 1 4 4 4 2 NACHT domain Mg_chelatase PF01078.16 OAJ23364.1 - 4.3e-07 29.2 2.3 0.017 14.2 0.0 2.8 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 OAJ23364.1 - 5e-07 29.8 0.0 0.019 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 OAJ23364.1 - 5.9e-07 29.6 0.0 0.047 13.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 OAJ23364.1 - 9e-07 28.4 5.7 0.23 10.8 0.1 4.6 2 2 2 4 4 4 2 AAA domain ABC_tran PF00005.22 OAJ23364.1 - 4.2e-06 27.0 0.0 0.076 13.3 0.0 3.0 3 0 0 3 3 2 2 ABC transporter AAA_19 PF13245.1 OAJ23364.1 - 4.5e-06 26.3 8.5 0.013 15.2 0.0 4.4 4 1 0 4 4 3 2 Part of AAA domain AAA_18 PF13238.1 OAJ23364.1 - 3e-05 24.3 0.0 0.2 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 OAJ23364.1 - 3.1e-05 23.5 0.0 0.052 13.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 OAJ23364.1 - 3.3e-05 23.9 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 OAJ23364.1 - 7.5e-05 22.2 0.1 0.44 10.0 0.0 4.0 5 0 0 5 5 4 1 Sigma-54 interaction domain KaiC PF06745.8 OAJ23364.1 - 8.7e-05 21.7 0.1 1.5 7.8 0.0 3.2 3 0 0 3 3 3 1 KaiC Viral_helicase1 PF01443.13 OAJ23364.1 - 0.00032 20.3 0.0 0.75 9.2 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 OAJ23364.1 - 0.00069 18.5 0.1 0.34 9.7 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain SKI PF01202.17 OAJ23364.1 - 0.0012 18.7 0.0 1.4 8.7 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase PhoH PF02562.11 OAJ23364.1 - 0.0014 17.8 0.2 1 8.5 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein Cytidylate_kin2 PF13189.1 OAJ23364.1 - 0.0023 17.8 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family Arch_ATPase PF01637.13 OAJ23364.1 - 0.0024 17.6 0.0 1.5 8.4 0.0 3.1 2 1 1 3 3 3 1 Archaeal ATPase Parvo_NS1 PF01057.12 OAJ23364.1 - 0.0025 16.7 0.1 1.6 7.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.8 OAJ23364.1 - 0.0029 16.5 0.0 0.03 13.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ResIII PF04851.10 OAJ23364.1 - 0.0035 17.1 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Rad17 PF03215.10 OAJ23364.1 - 0.0046 15.7 0.0 1.1 7.8 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein ATP-synt_ab PF00006.20 OAJ23364.1 - 0.005 16.3 0.0 0.59 9.5 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 OAJ23364.1 - 0.0057 16.2 0.8 3.4 7.3 0.0 2.7 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 Lzipper-MIP1 PF14389.1 OAJ23364.1 - 0.01 15.8 0.3 0.058 13.4 0.1 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 AAA_11 PF13086.1 OAJ23364.1 - 0.012 15.2 0.1 5.9 6.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain AFG1_ATPase PF03969.11 OAJ23364.1 - 0.012 14.4 0.3 1.4 7.6 0.0 2.6 3 0 0 3 3 2 0 AFG1-like ATPase AAA_24 PF13479.1 OAJ23364.1 - 0.022 14.3 0.2 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 OAJ23364.1 - 0.028 14.1 0.0 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 OAJ23364.1 - 0.067 12.6 0.0 9.1 5.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.13 OAJ23364.1 - 0.25 10.9 0.0 4.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein DUF2075 PF09848.4 OAJ23364.1 - 0.25 10.2 0.1 20 4.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TFIIA PF03153.8 OAJ23364.1 - 6 6.6 10.0 9.4 6.0 7.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fibrillarin PF01269.12 OAJ23379.1 - 2e-107 357.3 0.0 2.6e-107 356.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 OAJ23379.1 - 3.7e-05 23.3 0.0 5.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 OAJ23379.1 - 0.0021 17.6 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 OAJ23379.1 - 0.0087 15.6 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Shadoo PF14999.1 OAJ23379.1 - 3.7 7.4 13.3 7.2 6.4 9.2 1.5 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective 2_5_RNA_ligase2 PF13563.1 OAJ23380.1 - 0.12 12.0 0.7 0.13 11.9 0.5 1.0 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily Fungal_trans PF04082.13 OAJ23381.1 - 1.1e-28 99.8 0.0 2e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ23381.1 - 8.5e-10 38.3 6.5 1.5e-09 37.5 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1769 PF08588.5 OAJ23382.1 - 5e-17 61.5 0.2 8.5e-17 60.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) HSF_DNA-bind PF00447.12 OAJ23395.1 - 1.1e-34 118.7 0.5 1.6e-34 118.2 0.4 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding UPF0172 PF03665.8 OAJ23396.1 - 1e-42 145.8 0.0 1.3e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 OAJ23396.1 - 0.15 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SRF-TF PF00319.13 OAJ23397.1 - 8.1e-19 66.6 0.0 1.4e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) LZ_Tnp_IS66 PF13007.2 OAJ23418.1 - 0.58 10.8 15.7 0.072 13.7 4.8 2.2 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Sporozoite_P67 PF05642.6 OAJ23418.1 - 1 7.1 7.4 1.2 6.8 5.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_88 PF07470.8 OAJ23441.1 - 3.7e-15 55.8 0.6 7.8e-14 51.4 0.4 2.2 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Pil1 PF13805.1 OAJ23442.1 - 8.5e-25 87.4 0.4 1.8e-24 86.3 0.1 1.6 1 1 0 1 1 1 1 Eisosome component PIL1 Lzipper-MIP1 PF14389.1 OAJ23442.1 - 0.12 12.4 6.5 2.2 8.4 1.7 2.7 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 GAS PF13851.1 OAJ23442.1 - 0.12 11.4 2.0 0.32 10.1 1.4 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF747 PF05346.6 OAJ23443.1 - 4.4e-111 371.1 0.0 3.5e-99 331.9 0.2 2.0 2 0 0 2 2 2 2 Eukaryotic membrane protein family Pkinase PF00069.20 OAJ23483.1 - 1.4e-45 155.4 0.0 2.4e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ23483.1 - 1.8e-25 89.5 0.0 3.2e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ23483.1 - 0.00054 19.0 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Phage_GP20 PF06810.6 OAJ23483.1 - 0.0072 15.7 0.6 0.0072 15.7 0.4 2.2 2 0 0 2 2 2 1 Phage minor structural protein GP20 Filament PF00038.16 OAJ23483.1 - 0.0082 15.6 13.6 0.0082 15.6 9.4 2.2 1 1 0 2 2 2 1 Intermediate filament protein TcdB_N PF12918.2 OAJ23483.1 - 0.051 13.6 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain RIO1 PF01163.17 OAJ23483.1 - 0.08 12.2 0.1 0.08 12.2 0.1 2.2 2 0 0 2 2 2 0 RIO1 family Sec8_exocyst PF04048.9 OAJ23483.1 - 0.2 11.2 9.1 0.9 9.1 0.2 2.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Occludin_ELL PF07303.8 OAJ23483.1 - 0.21 12.3 6.8 1.9 9.2 0.0 2.5 2 0 0 2 2 2 0 Occludin homology domain TBPIP PF07106.8 OAJ23483.1 - 1.1 8.7 15.1 0.25 10.8 4.6 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2937 PF11157.3 OAJ23483.1 - 2.5 7.4 12.0 4.4 6.5 4.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) FlxA PF14282.1 OAJ23483.1 - 3.1 7.7 16.6 1.3 8.9 7.8 2.4 2 1 0 2 2 2 0 FlxA-like protein Viral_P18 PF04521.8 OAJ23483.1 - 3.6 7.0 13.1 3.8 6.9 0.2 3.1 2 1 1 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein PhoU PF01895.14 OAJ23483.1 - 5 7.6 9.2 3.9 8.0 1.0 2.9 2 1 1 3 3 3 0 PhoU domain HEAT_EZ PF13513.1 OAJ23504.1 - 3.1e-07 30.6 0.0 0.00086 19.7 0.0 2.8 2 1 1 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.1 OAJ23504.1 - 5.6e-05 23.3 0.1 0.0065 16.7 0.0 2.2 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 OAJ23504.1 - 0.00032 20.5 0.0 0.18 11.9 0.0 2.7 2 0 0 2 2 2 2 HEAT repeat Xpo1 PF08389.7 OAJ23504.1 - 0.049 13.5 0.0 0.4 10.5 0.0 2.2 1 1 1 2 2 2 0 Exportin 1-like protein CAS_CSE1 PF03378.10 OAJ23505.1 - 0.11 10.8 0.0 0.11 10.8 0.0 1.0 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Dynamitin PF04912.9 OAJ23505.1 - 0.13 11.0 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Dynamitin Cytochrom_NNT PF03264.9 OAJ23507.1 - 0.048 13.0 0.5 0.077 12.4 0.1 1.5 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region tRNA-synt_1 PF00133.17 OAJ23510.1 - 2.8e-06 25.6 0.0 3.1e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 OAJ23510.1 - 0.039 13.2 0.0 0.045 13.0 0.0 1.0 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 RVT_1 PF00078.22 OAJ23529.1 - 2.1e-10 40.3 0.0 5.7e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) OGG_N PF07934.7 OAJ23553.1 - 8.8e-22 77.2 0.0 5e-21 74.8 0.0 2.1 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain NmrA PF05368.8 OAJ23553.1 - 5.1e-11 42.2 0.0 0.00043 19.6 0.0 3.3 3 0 0 3 3 3 3 NmrA-like family HhH-GPD PF00730.20 OAJ23553.1 - 1.1e-09 38.5 0.0 2.3e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 OAJ23553.1 - 0.00071 19.1 0.0 0.0022 17.5 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif NAD_binding_10 PF13460.1 OAJ23553.1 - 0.0046 16.9 0.1 0.056 13.4 0.0 2.6 2 1 0 2 2 2 1 NADH(P)-binding Orn_Arg_deC_N PF02784.11 OAJ23570.1 - 2.6e-69 233.2 0.0 3.6e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 OAJ23570.1 - 6.8e-29 99.9 0.0 1.3e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain B12-binding PF02310.14 OAJ23570.1 - 0.04 13.7 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain zf-C2H2_jaz PF12171.3 OAJ23571.1 - 2.2e-09 37.1 2.2 3.8e-09 36.4 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAJ23571.1 - 6.5e-06 26.1 1.3 1e-05 25.5 0.9 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 OAJ23571.1 - 0.00082 19.4 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Bot1p PF12298.3 OAJ23571.1 - 0.034 14.1 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein AKAP95 PF04988.7 OAJ23571.1 - 0.058 13.1 1.0 0.068 12.9 0.1 1.5 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.21 OAJ23571.1 - 0.12 12.7 2.3 0.12 12.7 1.6 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Sulfate_transp PF00916.15 OAJ23596.1 - 4.9e-22 78.2 1.6 7.9e-22 77.5 1.1 1.3 1 0 0 1 1 1 1 Sulfate transporter family DUF350 PF03994.9 OAJ23596.1 - 0.049 13.3 0.1 0.049 13.3 0.1 2.9 2 1 1 3 3 3 0 Domain of Unknown Function (DUF350) SPW PF03779.9 OAJ23596.1 - 0.12 11.7 6.0 1.7 8.0 0.1 2.7 2 0 0 2 2 2 0 SPW repeat DUF2910 PF11139.3 OAJ23596.1 - 0.12 11.4 9.6 1.5 7.9 6.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2910) DUF3975 PF13126.1 OAJ23620.1 - 0.42 10.8 5.3 0.18 11.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) Cys_Met_Meta_PP PF01053.15 OAJ23622.1 - 2.9e-53 180.5 0.0 1.8e-45 154.9 0.0 2.3 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 OAJ23622.1 - 0.066 11.9 0.1 0.13 10.9 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-V Aminotran_1_2 PF00155.16 OAJ23622.1 - 0.08 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II EPSP_synthase PF00275.15 OAJ23644.1 - 0.0023 16.4 0.0 0.0035 15.8 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) MULE PF10551.4 OAJ23645.1 - 5.7e-07 29.6 0.0 1.6e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 OAJ23645.1 - 1.9e-06 28.3 0.2 8.7e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 FAR1 DNA-binding domain SWIM PF04434.12 OAJ23645.1 - 0.00052 19.4 0.2 0.0011 18.3 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger Phage_integrase PF00589.17 OAJ23662.1 - 0.00032 20.4 0.0 0.00048 19.8 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Glyco_hydro_85 PF03644.8 OAJ23663.1 - 6e-10 38.7 0.2 9.1e-10 38.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 TPR_12 PF13424.1 OAJ23689.1 - 0.00029 20.6 23.3 2.3 8.2 0.0 7.5 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ23689.1 - 0.24 11.0 12.7 5.4 6.7 0.0 5.8 4 2 3 7 7 7 0 TPR repeat TPR_2 PF07719.12 OAJ23689.1 - 3.8 7.6 16.8 7.3 6.7 0.0 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ23689.1 - 5.2 7.7 7.4 15 6.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat E1-E2_ATPase PF00122.15 OAJ23690.1 - 1.6e-14 53.5 3.8 3e-14 52.6 0.0 2.7 2 1 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 OAJ23690.1 - 6.1e-14 52.6 0.2 2.5e-13 50.6 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAJ23690.1 - 1.1e-13 52.1 0.4 7.9e-12 46.0 0.3 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ23690.1 - 9.8e-12 44.6 0.0 2.2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAJ23690.1 - 0.002 17.7 0.1 0.0054 16.3 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Exo_endo_phos PF03372.18 OAJ23710.1 - 7.1e-20 71.9 0.1 1.6e-19 70.8 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 OAJ23710.1 - 2.2e-15 55.8 5.0 3.9e-07 29.5 0.2 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ23710.1 - 2e-08 33.8 5.9 3.6e-05 23.4 0.7 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 OAJ23710.1 - 5.8e-05 22.5 3.4 0.26 11.4 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 OAJ23710.1 - 0.00012 21.6 6.5 0.33 11.3 0.0 4.1 4 0 0 4 4 4 2 Leucine rich repeat CENP-B_dimeris PF09026.5 OAJ23710.1 - 0.026 14.7 1.8 0.08 13.1 1.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Steroid_dh PF02544.11 OAJ23711.1 - 5e-23 81.5 1.9 9.4e-08 31.9 0.0 4.2 3 1 1 4 4 4 4 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 OAJ23711.1 - 0.0078 15.5 0.1 0.02 14.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Pkinase PF00069.20 OAJ23712.1 - 3.5e-41 141.0 0.0 8.2e-27 93.9 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ23712.1 - 2.2e-16 59.7 0.0 7.1e-14 51.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 OAJ23712.1 - 0.00045 20.0 0.3 1 9.0 0.1 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pam16 PF03656.8 OAJ23713.1 - 4.7e-11 42.5 11.4 1.8e-06 27.7 7.9 4.0 1 1 0 1 1 1 1 Pam16 SR-25 PF10500.4 OAJ23713.1 - 8.5 5.7 12.0 7.5 5.9 2.4 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 OAJ23733.1 - 0.085 10.8 10.1 0.14 10.1 7.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 OAJ23733.1 - 1.6 6.8 23.3 0.25 9.5 9.8 2.2 2 0 0 2 2 2 0 Transmembrane protein Mpp10 PF04006.7 OAJ23734.1 - 7.9e-67 225.9 0.1 9.5e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Mpp10 protein Peptidase_C1_2 PF03051.10 OAJ23735.1 - 2e-134 448.4 0.0 5.4e-133 443.7 0.0 2.0 1 1 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 OAJ23735.1 - 6.1e-06 26.2 0.0 0.00056 19.8 0.1 2.3 2 0 0 2 2 2 2 Papain family cysteine protease BRO1 PF03097.13 OAJ23754.1 - 7.1e-05 21.7 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain Methyltransf_26 PF13659.1 OAJ23755.1 - 0.017 15.1 0.0 0.017 15.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 OAJ23755.1 - 0.064 12.8 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DEAD PF00270.24 OAJ23757.1 - 0.00078 18.9 0.0 0.0009 18.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Lipase_3 PF01764.20 OAJ23758.1 - 0.00011 21.8 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Candida_ALS PF05792.8 OAJ23758.1 - 0.26 11.4 2.7 7.7 6.7 0.2 2.5 2 0 0 2 2 2 0 Candida agglutinin-like (ALS) CDV3 PF15359.1 OAJ23759.1 - 2.3 8.2 15.2 1.6 8.7 9.3 1.5 1 1 0 1 1 1 0 Carnitine deficiency-associated protein 3 DUF605 PF04652.11 OAJ23759.1 - 2.8 7.2 15.0 3.4 6.9 10.4 1.2 1 0 0 1 1 1 0 Vta1 like Aldedh PF00171.17 OAJ23778.1 - 9.4e-125 416.5 0.1 1.2e-124 416.1 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAJ23778.1 - 0.093 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) WD40 PF00400.27 OAJ23779.1 - 0.0017 18.1 2.8 0.14 12.1 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat WD40 PF00400.27 OAJ23780.1 - 1.1e-73 240.7 31.9 1.1e-08 34.5 0.4 12.0 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp13 PF08625.6 OAJ23780.1 - 4.4e-29 100.9 0.0 3.3e-18 65.6 0.0 2.3 2 0 0 2 2 2 2 Utp13 specific WD40 associated domain Nup160 PF11715.3 OAJ23780.1 - 4.3e-08 31.7 9.2 0.29 9.2 0.4 5.8 3 2 2 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAJ23780.1 - 2.5e-05 23.2 1.0 0.06 12.0 0.0 4.4 4 2 1 5 5 5 2 Nup133 N terminal like Metallophos PF00149.23 OAJ23781.1 - 7.8e-40 136.4 0.3 9.6e-40 136.1 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAJ23781.1 - 0.0043 16.9 0.0 0.0053 16.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2268 PF10026.4 OAJ23781.1 - 0.056 12.8 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) RRM_1 PF00076.17 OAJ23798.1 - 2.5e-18 65.4 0.0 3.4e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ23798.1 - 6.9e-14 51.5 0.0 9.4e-14 51.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ23798.1 - 6.8e-10 38.6 0.0 9.9e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MRC1 PF09444.5 OAJ23799.1 - 3.5e-17 63.0 20.7 3.5e-17 63.0 14.3 5.4 5 1 0 5 5 5 1 MRC1-like domain GP38 PF05268.6 OAJ23799.1 - 0.66 9.3 10.9 1.1 8.6 7.5 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 DUF4254 PF14063.1 OAJ23800.1 - 0.085 12.4 1.1 0.18 11.4 0.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4254) DUF904 PF06005.7 OAJ23800.1 - 0.29 11.4 4.2 0.39 11.0 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF465 PF04325.8 OAJ23800.1 - 0.44 10.2 5.1 1.7 8.4 3.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF465) CTP_transf_1 PF01148.15 OAJ23801.1 - 0.0004 20.1 3.4 0.0004 20.1 2.3 4.4 2 2 1 4 4 4 2 Cytidylyltransferase family IBN_N PF03810.14 OAJ23817.1 - 1.8e-07 31.0 0.0 2.3e-05 24.2 0.0 3.4 2 1 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 OAJ23817.1 - 0.0076 16.1 0.1 0.19 11.6 0.0 3.2 2 1 0 2 2 2 1 Exportin 1-like protein Arf PF00025.16 OAJ23818.1 - 4e-36 123.8 0.0 1.4e-24 86.3 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 OAJ23818.1 - 3.5e-13 49.2 0.0 1.6e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 OAJ23818.1 - 2.9e-08 33.1 0.0 5.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 OAJ23818.1 - 2.6e-07 31.1 0.0 8e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 OAJ23818.1 - 6.5e-06 25.4 0.0 9.2e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 OAJ23818.1 - 1.5e-05 23.9 0.0 2.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 OAJ23818.1 - 0.00047 20.1 0.0 0.00072 19.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 OAJ23818.1 - 0.044 13.5 0.1 0.089 12.6 0.1 1.5 2 0 0 2 2 2 0 Dynamin family GTP_EFTU PF00009.22 OAJ23818.1 - 0.11 11.9 0.0 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DPBB_1 PF03330.13 OAJ23819.1 - 0.00029 20.7 0.1 0.0016 18.4 0.1 2.1 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ23819.1 - 0.0095 15.6 0.1 0.013 15.1 0.1 1.2 1 0 0 1 1 1 1 Barwin family TPR_14 PF13428.1 OAJ23820.1 - 0.16 12.6 0.9 0.41 11.4 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat PUF PF00806.14 OAJ23842.1 - 3.1e-59 193.2 2.8 4.1e-10 38.5 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Fer2_3 PF13085.1 OAJ23843.1 - 1e-31 108.9 0.0 1.6e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 OAJ23843.1 - 7.9e-10 38.9 6.2 7.9e-10 38.9 4.3 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 OAJ23843.1 - 2.8e-09 36.8 5.0 2.8e-09 36.8 3.5 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 OAJ23843.1 - 0.00015 22.1 3.1 0.00015 22.1 2.1 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 OAJ23843.1 - 0.00018 21.6 5.5 0.041 14.1 0.4 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 OAJ23843.1 - 0.00027 20.6 4.5 0.00027 20.6 3.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 OAJ23843.1 - 0.011 15.4 1.4 0.011 15.4 1.0 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 OAJ23843.1 - 0.019 15.3 6.4 0.019 15.3 4.4 2.6 2 2 2 4 4 4 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 OAJ23843.1 - 0.17 12.4 5.2 1.8 9.1 0.2 2.9 3 0 0 3 3 3 0 4Fe-4S single cluster domain DNA_pol3_tau_4 PF12168.3 OAJ23843.1 - 0.87 10.0 3.7 1.3 9.4 0.7 2.3 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Tetraspannin PF00335.15 OAJ23844.1 - 2.3e-17 63.0 8.5 2.9e-17 62.6 5.9 1.1 1 0 0 1 1 1 1 Tetraspanin family Glyco_hydro_18 PF00704.23 OAJ23865.1 - 4.7e-45 154.5 0.0 6.1e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TarH PF02203.10 OAJ23866.1 - 0.039 13.7 0.0 0.044 13.6 0.0 1.0 1 0 0 1 1 1 0 Tar ligand binding domain homologue Ribosomal_S4 PF00163.14 OAJ23888.1 - 3.4e-12 46.5 0.5 4.9e-12 46.0 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 OAJ23888.1 - 1.5e-10 40.3 0.0 2.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 S4 domain Peptidase_M24 PF00557.19 OAJ23889.1 - 7.2e-49 166.1 0.0 1e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 OAJ23889.1 - 1.1e-34 118.7 0.0 1.9e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.19 OAJ23890.1 - 8.2e-41 139.8 0.0 1.2e-40 139.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 OAJ23890.1 - 6.2e-20 72.0 0.0 5.2e-19 69.0 0.0 2.4 2 1 1 3 3 3 1 Creatinase/Prolidase N-terminal domain Xan_ur_permease PF00860.15 OAJ23891.1 - 1.8e-54 184.7 30.8 4.4e-53 180.1 21.4 2.1 1 1 0 1 1 1 1 Permease family RNA_pol_A_bac PF01000.21 OAJ23892.1 - 9.5e-27 93.3 0.0 2.1e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 OAJ23892.1 - 7.1e-19 66.6 0.0 9.4e-19 66.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 OAJ23892.1 - 0.00044 19.7 0.1 0.0053 16.2 0.0 2.6 2 1 1 3 3 3 1 Domain of unknown function DUF22 Formyl_trans_N PF00551.14 OAJ23911.1 - 1.4e-32 112.6 0.0 4.3e-18 65.4 0.1 2.0 1 1 1 2 2 2 2 Formyl transferase DUF3367 PF11847.3 OAJ23911.1 - 0.1 10.5 0.0 0.14 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) RhoGEF PF00621.15 OAJ23912.1 - 8.3e-16 58.3 0.0 3.4e-12 46.6 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain Chromo PF00385.19 OAJ23912.1 - 9.2e-08 31.6 3.1 9.2e-08 31.6 2.1 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 OAJ23912.1 - 2.8e-06 27.0 0.0 7.3e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Chromo shadow domain Ribosomal_L7Ae PF01248.21 OAJ23913.1 - 1.1e-21 76.1 0.2 1.7e-21 75.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 OAJ23913.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 Arch_ATPase PF01637.13 OAJ23913.1 - 0.11 12.2 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Archaeal ATPase Transposase_21 PF02992.9 OAJ23933.1 - 8.3e-13 47.9 0.0 1.2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 PspB PF06667.7 OAJ23934.1 - 0.0022 17.8 1.3 0.0022 17.8 0.9 3.2 2 1 1 3 3 3 1 Phage shock protein B FlaC_arch PF05377.6 OAJ23934.1 - 0.048 13.5 6.9 0.52 10.2 0.4 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) FlxA PF14282.1 OAJ23934.1 - 0.14 12.0 11.0 0.62 10.0 2.9 2.4 1 1 1 2 2 2 0 FlxA-like protein Peptidase_S46 PF10459.4 OAJ23934.1 - 0.46 8.8 16.7 0.6 8.4 11.5 1.0 1 0 0 1 1 1 0 Peptidase S46 DivIC PF04977.10 OAJ23934.1 - 1 8.8 18.4 0.04 13.4 2.1 2.9 3 0 0 3 3 3 0 Septum formation initiator AKNA PF12443.3 OAJ23934.1 - 2.2 8.3 10.7 0.37 10.8 0.4 2.9 1 1 1 3 3 3 0 AT-hook-containing transcription factor DNA_pol3_a_NII PF11490.3 OAJ23934.1 - 5.3 6.6 9.5 6.4 6.4 1.8 2.5 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II TSC22 PF01166.13 OAJ23934.1 - 6.5 6.8 11.4 2.3 8.2 0.8 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family Peptidase_M35 PF02102.10 OAJ23936.1 - 0.54 8.8 3.6 0.62 8.6 2.5 1.1 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Flavoprotein PF02441.14 OAJ23956.1 - 1.3e-39 134.8 0.0 1.7e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein TPR_11 PF13414.1 OAJ23957.1 - 1.8e-22 78.7 2.9 9.9e-08 31.5 0.0 3.6 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 OAJ23957.1 - 9.3e-19 66.1 2.5 1.4e-06 27.5 0.0 4.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ23957.1 - 7.3e-18 62.9 3.5 1.5e-05 24.5 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ23957.1 - 2.5e-13 50.2 8.2 2.1e-07 31.4 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ23957.1 - 4.6e-13 49.3 0.4 1.6e-05 25.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ23957.1 - 4e-11 42.5 12.4 0.034 14.7 0.0 6.1 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ23957.1 - 5e-11 41.5 2.3 0.021 14.5 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ23957.1 - 7.4e-11 41.8 3.8 6.3e-05 22.8 0.0 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ23957.1 - 1.8e-10 40.1 0.6 0.051 13.7 0.0 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ23957.1 - 2.2e-09 37.1 0.1 0.00026 21.2 0.0 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ23957.1 - 1.1e-06 28.3 0.1 0.00084 19.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ23957.1 - 3.3e-06 26.4 2.1 0.37 10.7 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ23957.1 - 3.3e-05 23.9 0.4 0.011 15.8 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 SPATA24 PF15175.1 OAJ23957.1 - 0.026 14.2 2.5 0.03 14.0 0.2 2.1 2 1 0 2 2 2 0 Spermatogenesis-associated protein 24 TPR_5 PF12688.2 OAJ23957.1 - 0.05 13.6 2.5 0.17 11.9 0.7 2.3 2 1 0 2 2 2 0 Tetratrico peptide repeat TPR_10 PF13374.1 OAJ23957.1 - 0.074 13.0 3.1 12 5.9 0.3 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF2580 PF10824.3 OAJ23957.1 - 4.4 7.7 8.5 1.1 9.7 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) RTC4 PF14474.1 OAJ23958.1 - 2.5e-09 37.1 0.0 5.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain VanZ PF04892.7 OAJ23977.1 - 2.6e-08 33.8 1.2 5e-08 32.9 0.9 1.5 1 1 0 1 1 1 1 VanZ like family HECT PF00632.20 OAJ23978.1 - 5e-92 308.4 0.0 7.4e-92 307.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 OAJ23978.1 - 1.9e-32 110.7 14.6 1.6e-10 40.6 1.9 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.25 OAJ23978.1 - 2.1e-14 53.0 0.1 4.8e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 C2 domain Complex1_LYR PF05347.10 OAJ23979.1 - 1.5e-05 24.7 0.3 3.4e-05 23.5 0.2 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAJ23979.1 - 9.7e-05 22.4 0.2 0.00029 20.9 0.1 1.8 1 0 0 1 1 1 1 Complex1_LYR-like Tctex-1 PF03645.8 OAJ23980.1 - 3.1e-09 36.5 0.0 3.8e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Totivirus_coat PF05518.6 OAJ23980.1 - 6.1 4.5 11.5 7.4 4.2 8.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein RCR PF12273.3 OAJ23981.1 - 8.3e-06 26.3 5.3 1.8e-05 25.3 3.7 1.5 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM51 PF15345.1 OAJ23981.1 - 0.00018 21.2 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 Shisa PF13908.1 OAJ23981.1 - 0.0011 19.1 0.2 0.0025 18.0 0.2 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 OAJ23981.1 - 0.003 15.9 0.0 0.0032 15.8 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E GRP PF07172.6 OAJ23981.1 - 0.0077 16.6 2.2 0.017 15.6 1.5 1.5 1 1 0 1 1 1 1 Glycine rich protein family EphA2_TM PF14575.1 OAJ23981.1 - 0.0079 16.5 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Sensor PF13796.1 OAJ23981.1 - 0.014 14.9 3.7 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 Putative sensor Rax2 PF12768.2 OAJ23981.1 - 0.023 13.9 0.1 0.029 13.5 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF3094 PF11293.3 OAJ23981.1 - 0.029 13.8 0.1 0.048 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) DUF3357 PF11837.3 OAJ23981.1 - 0.057 13.2 0.9 0.12 12.2 0.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) TMEM154 PF15102.1 OAJ23981.1 - 0.059 13.0 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family PgaD PF13994.1 OAJ23981.1 - 0.082 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 PgaD-like protein Mid2 PF04478.7 OAJ23981.1 - 0.17 11.3 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF1049 PF06305.6 OAJ23981.1 - 1.2 8.7 7.0 0.47 9.9 2.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) DUF912 PF06024.7 OAJ23981.1 - 2.2 8.3 4.3 0.72 9.9 0.2 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) IncA PF04156.9 OAJ23981.1 - 6 6.4 6.3 0.54 9.8 0.1 1.9 2 0 0 2 2 2 0 IncA protein DUF1180 PF06679.7 OAJ23981.1 - 6.2 6.6 12.2 1.1 9.1 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) UBN2_2 PF14227.1 OAJ24001.1 - 1.9e-07 30.6 0.0 2.5e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ24001.1 - 9.3e-07 28.6 0.1 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type CoaE PF01121.15 OAJ24001.1 - 0.052 12.9 0.0 0.06 12.7 0.0 1.1 1 0 0 1 1 1 0 Dephospho-CoA kinase Pkinase PF00069.20 OAJ24028.1 - 2.4e-72 243.2 0.0 3.3e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ24028.1 - 2.5e-36 125.0 0.0 3.8e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ24028.1 - 1.5e-07 30.6 0.0 3.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like UBA_2 PF08587.6 OAJ24028.1 - 0.0073 16.4 0.4 0.025 14.7 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) RIO1 PF01163.17 OAJ24028.1 - 0.02 14.2 0.1 0.042 13.1 0.1 1.5 1 0 0 1 1 1 0 RIO1 family PLA2_B PF01735.13 OAJ24029.1 - 5.4e-14 51.2 0.0 8.7e-07 27.4 0.0 3.2 3 0 0 3 3 3 3 Lysophospholipase catalytic domain G-alpha PF00503.15 OAJ24044.1 - 2.6e-79 266.7 0.0 2.4e-52 177.9 0.0 3.2 3 0 0 3 3 3 3 G-protein alpha subunit Arf PF00025.16 OAJ24044.1 - 5.8e-10 38.6 0.0 9.4e-06 24.9 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.1 OAJ24044.1 - 0.002 18.2 0.0 0.038 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 OAJ24044.1 - 0.0045 17.4 0.0 0.035 14.5 0.0 2.4 3 0 0 3 3 3 1 Miro-like protein Zeta_toxin PF06414.7 OAJ24044.1 - 0.006 15.7 0.0 0.027 13.5 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.22 OAJ24044.1 - 0.006 16.8 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 OAJ24044.1 - 0.0084 15.6 0.0 0.15 11.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 OAJ24044.1 - 0.011 15.2 0.0 0.32 10.4 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 OAJ24044.1 - 0.021 14.4 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 OAJ24044.1 - 0.091 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RVT_1 PF00078.22 OAJ24045.1 - 2.5e-15 56.3 0.0 4.7e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ24045.1 - 2e-11 44.0 0.0 4.3e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ24045.1 - 0.00079 19.8 0.0 0.0021 18.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ24045.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DRIM PF07539.7 OAJ24064.1 - 1.9e-43 147.2 0.0 6.5e-43 145.5 0.0 2.1 1 0 0 1 1 1 1 Down-regulated in metastasis ParcG PF10274.4 OAJ24064.1 - 0.034 14.0 0.5 0.73 9.7 0.0 2.7 2 0 0 2 2 2 0 Parkin co-regulated protein Sec7_N PF12783.2 OAJ24064.1 - 0.12 11.8 4.1 0.35 10.2 0.0 3.6 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal SURF2 PF05477.6 OAJ24084.1 - 0.011 14.9 5.2 0.018 14.1 3.6 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Daxx PF03344.10 OAJ24084.1 - 0.011 14.2 6.5 0.013 14.0 4.5 1.0 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 OAJ24084.1 - 0.088 10.8 4.8 0.099 10.6 3.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Colicin_D PF11429.3 OAJ24084.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Colicin D DUF2106 PF09879.4 OAJ24105.1 - 0.019 14.2 0.2 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) Flavin_Reduct PF01613.13 OAJ24106.1 - 1.2e-24 86.8 0.0 1.7e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain BCS1_N PF08740.6 OAJ24107.1 - 1.6e-49 168.0 0.0 2.9e-49 167.2 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 OAJ24107.1 - 5.8e-17 62.1 0.0 1.8e-16 60.5 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 OAJ24107.1 - 0.00014 22.6 0.0 0.00034 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 OAJ24107.1 - 0.00029 19.8 0.0 0.00063 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 OAJ24107.1 - 0.002 17.6 0.2 0.0092 15.4 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ24107.1 - 0.0022 17.9 1.3 0.015 15.2 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.1 OAJ24107.1 - 0.0035 17.3 0.0 0.0055 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAJ24107.1 - 0.004 16.5 0.0 0.021 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAJ24107.1 - 0.017 15.2 0.0 0.047 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 OAJ24107.1 - 0.032 13.9 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 OAJ24107.1 - 0.038 14.2 0.1 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 OAJ24107.1 - 0.056 13.3 0.2 0.21 11.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAJ24107.1 - 0.083 12.6 0.6 0.58 9.9 0.0 2.8 3 0 0 3 3 2 0 Part of AAA domain AAA_24 PF13479.1 OAJ24107.1 - 0.098 12.2 0.1 0.3 10.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 OAJ24107.1 - 0.1 11.6 0.0 0.37 9.8 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.18 OAJ24107.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Keratin_matx PF04579.7 OAJ24108.1 - 3.4 7.9 8.0 1.5 9.1 0.7 3.0 3 0 0 3 3 3 0 Keratin, high-sulphur matrix protein Gtr1_RagA PF04670.7 OAJ24123.1 - 6e-35 120.4 0.0 8.1e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 OAJ24123.1 - 0.00093 18.9 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase MMR_HSR1 PF01926.18 OAJ24123.1 - 0.0025 17.7 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAJ24123.1 - 0.007 16.8 0.0 0.021 15.3 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 OAJ24123.1 - 0.017 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 OAJ24123.1 - 0.021 14.7 0.0 0.053 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 OAJ24123.1 - 0.043 13.0 0.0 0.22 10.7 0.0 2.1 1 1 0 1 1 1 0 ADP-ribosylation factor family RRM_1 PF00076.17 OAJ24124.1 - 1.4e-10 40.6 0.0 0.00022 20.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ24124.1 - 2.2e-10 40.3 0.0 0.00031 20.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.8 OAJ24124.1 - 0.0035 17.2 25.1 0.039 13.8 9.6 2.5 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Cuticle_1 PF08140.6 OAJ24124.1 - 0.043 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Cytochrom_B561 PF03188.11 OAJ24125.1 - 9.9e-08 31.9 11.3 9.9e-08 31.9 7.9 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.12 OAJ24125.1 - 1.4e-05 25.0 1.5 2.6e-05 24.1 0.8 1.7 1 1 1 2 2 2 1 DOMON domain DUF2427 PF10348.4 OAJ24125.1 - 0.015 14.8 4.7 0.072 12.6 3.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) Thioredoxin PF00085.15 OAJ24126.1 - 2.7e-09 36.6 0.0 3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin HLH PF00010.21 OAJ24149.1 - 0.12 12.1 0.7 0.23 11.1 0.5 1.4 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Sec66 PF09802.4 OAJ24149.1 - 0.17 11.2 1.1 0.26 10.6 0.8 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 AMP-binding PF00501.23 OAJ24150.1 - 2.4e-72 243.6 0.0 3.4e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.19 OAJ24150.1 - 1.8e-05 23.9 7.2 0.61 9.6 0.2 7.1 8 1 0 8 8 8 2 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.20 OAJ24150.1 - 0.0056 16.9 0.0 0.015 15.5 0.0 1.8 1 1 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.1 OAJ24150.1 - 3.5 7.2 9.3 0.87 9.2 0.2 4.6 6 1 1 7 7 7 0 Hexapeptide repeat of succinyl-transferase Vanabin-2 PF11437.3 OAJ24177.1 - 0.09 12.7 9.4 0.12 12.3 6.5 1.2 1 0 0 1 1 1 0 Vanadium-binding protein 2 STAG PF08514.6 OAJ24178.1 - 8.3e-31 106.1 1.0 3e-30 104.3 0.7 2.0 1 0 0 1 1 1 1 STAG domain WD40 PF00400.27 OAJ24179.1 - 1.6e-55 183.1 26.3 3.3e-10 39.4 0.0 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 OAJ24179.1 - 2.5e-14 53.4 1.0 8.4e-08 32.1 0.1 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 OAJ24179.1 - 0.019 13.7 0.0 0.039 12.7 0.0 1.5 1 1 0 1 1 1 0 Coatomer WD associated region Cytochrom_D1 PF02239.11 OAJ24179.1 - 0.068 11.4 0.0 0.14 10.4 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF4340 PF14238.1 OAJ24179.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4340) Polysacc_deac_1 PF01522.16 OAJ24200.1 - 1.2e-27 95.9 0.0 2e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase cobW PF02492.14 OAJ24220.1 - 1.4e-33 115.8 0.0 1.9e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 OAJ24220.1 - 7e-06 25.0 1.7 2.1e-05 23.4 1.2 1.6 1 1 0 1 1 1 1 ArgK protein GTP_EFTU PF00009.22 OAJ24220.1 - 0.0066 15.9 0.0 1.1 8.6 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 OAJ24220.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 OAJ24220.1 - 0.015 15.5 0.1 0.035 14.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 OAJ24220.1 - 0.019 15.8 0.0 0.036 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAJ24220.1 - 0.049 13.3 0.1 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 OAJ24220.1 - 0.077 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.22 OAJ24220.1 - 0.094 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 OAJ24220.1 - 0.11 12.4 0.0 0.59 10.1 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase T2SE PF00437.15 OAJ24220.1 - 0.13 11.1 0.0 0.28 10.0 0.0 1.4 1 1 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 OAJ24220.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.9 OAJ24220.1 - 0.17 10.8 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain SelP_N PF04592.9 OAJ24220.1 - 0.36 10.1 10.2 0.52 9.6 7.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 OAJ24220.1 - 3.3 6.6 6.6 4.5 6.1 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ufd2P_core PF10408.4 OAJ24221.1 - 2.3e-177 591.0 0.0 2.8e-177 590.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 OAJ24221.1 - 4.1e-26 90.7 0.4 1.3e-25 89.1 0.3 2.0 1 0 0 1 1 1 1 U-box domain HutP PF09021.6 OAJ24222.1 - 0.33 11.1 4.4 2 8.6 0.2 2.5 2 1 0 2 2 2 0 HutP Ten1_2 PF15490.1 OAJ24223.1 - 4.1e-06 26.3 0.0 2.3e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit RNA_Me_trans PF04252.8 OAJ24224.1 - 9.4e-18 64.3 0.0 8e-15 54.7 0.0 3.0 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase adh_short PF00106.20 OAJ24248.1 - 8e-64 214.5 12.4 5.1e-32 111.1 2.8 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 OAJ24248.1 - 1.5e-28 99.7 7.6 6.3e-14 52.0 0.3 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 OAJ24248.1 - 1.1e-27 95.8 0.0 2.4e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 OAJ24248.1 - 2.2e-10 40.4 0.0 1.2e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 2-Hacid_dh_C PF02826.14 OAJ24248.1 - 7.7e-06 25.1 2.2 0.072 12.2 0.1 2.9 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 OAJ24248.1 - 0.00017 20.6 0.8 0.11 11.5 0.2 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 OAJ24248.1 - 0.0015 18.2 9.3 0.055 13.1 1.2 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF543 PF04418.7 OAJ24248.1 - 0.057 13.3 5.7 0.87 9.5 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF543) DUF3887 PF13026.1 OAJ24248.1 - 0.058 13.6 0.2 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) DHHA1 PF02272.14 OAJ24248.1 - 0.088 12.5 6.8 0.034 13.8 2.2 2.3 2 0 0 2 2 2 0 DHHA1 domain YjeF_N PF03853.10 OAJ24248.1 - 0.45 10.1 6.0 0.37 10.3 0.4 2.4 2 0 0 2 2 2 0 YjeF-related protein N-terminus Mur_ligase PF01225.20 OAJ24248.1 - 0.87 9.7 5.7 0.65 10.1 0.1 3.2 2 1 1 3 3 3 0 Mur ligase family, catalytic domain Pkinase PF00069.20 OAJ24250.1 - 2.1e-52 177.8 0.0 3.4e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ24250.1 - 4.4e-48 163.5 0.0 5.9e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ24250.1 - 0.013 15.2 1.2 0.049 13.3 0.0 2.6 2 2 0 2 2 2 0 Phosphotransferase enzyme family TLP-20 PF06088.6 OAJ24250.1 - 4.4 6.9 8.3 0.22 11.1 0.2 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) zf-RanBP PF00641.13 OAJ24277.1 - 9e-12 43.8 10.8 4e-07 29.0 0.7 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others W2 PF02020.13 OAJ24298.1 - 1.7e-17 63.1 0.3 1.7e-17 63.1 0.2 2.3 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon FAD_binding_1 PF00667.15 OAJ24299.1 - 1.7e-55 187.8 0.0 3.7e-55 186.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 OAJ24299.1 - 9.5e-32 109.9 0.2 2e-31 108.9 0.1 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 OAJ24299.1 - 5.7e-21 75.1 0.0 2.4e-20 73.0 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain zf-Nse PF11789.3 OAJ24301.1 - 6.7e-14 51.1 0.1 1.3e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 OAJ24301.1 - 0.0056 16.6 0.0 0.026 14.4 0.0 2.1 2 0 0 2 2 2 1 U-box domain DUF3246 PF11596.3 OAJ24301.1 - 0.013 14.8 5.3 0.029 13.6 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) zf-RING_UBOX PF13445.1 OAJ24301.1 - 0.019 14.6 0.0 0.056 13.1 0.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Snapin_Pallidin PF14712.1 OAJ24301.1 - 0.1 12.9 1.2 0.23 11.7 0.8 1.6 1 0 0 1 1 1 0 Snapin/Pallidin Pkinase PF00069.20 OAJ24325.1 - 2.3e-19 69.5 0.0 3.6e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ24325.1 - 4.3e-11 42.3 0.0 5.7e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 OAJ24325.1 - 0.0054 15.8 0.1 0.013 14.5 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_pol_viral_C PF00336.13 OAJ24325.1 - 0.011 15.0 0.1 0.08 12.1 0.0 2.4 2 1 0 2 2 2 0 DNA polymerase (viral) C-terminal domain RVT_3 PF13456.1 OAJ24325.1 - 0.045 13.5 0.1 0.28 10.9 0.1 2.2 2 0 0 2 2 2 0 Reverse transcriptase-like Bul1_N PF04425.7 OAJ24325.1 - 0.13 10.7 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Bul1 N terminus HisK_N PF09385.5 OAJ24326.1 - 0.071 12.7 0.3 0.18 11.4 0.2 1.6 1 0 0 1 1 1 0 Histidine kinase N terminal PspA_IM30 PF04012.7 OAJ24326.1 - 7.4 5.8 50.9 1.8 7.8 5.6 3.4 3 1 1 4 4 4 0 PspA/IM30 family Dimer_Tnp_hAT PF05699.9 OAJ24350.1 - 1.1e-20 73.0 0.1 2.1e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Abhydrolase_5 PF12695.2 OAJ24374.1 - 1.4e-06 28.1 0.1 6.4e-06 25.9 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ24374.1 - 3.1e-06 27.2 2.0 4.8e-06 26.6 1.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 OAJ24374.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.13 OAJ24374.1 - 0.052 12.8 0.0 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family ACBP PF00887.14 OAJ24375.1 - 3.4e-32 109.9 0.2 4.9e-32 109.4 0.1 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Tox-REase-5 PF15648.1 OAJ24375.1 - 0.063 13.5 0.6 0.085 13.1 0.4 1.3 1 1 0 1 1 1 0 Restriction endonuclease fold toxin 5 DUF221 PF02714.10 OAJ24376.1 - 7e-98 327.4 18.0 1e-97 326.9 12.5 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAJ24376.1 - 5e-35 120.3 2.2 5e-35 120.3 1.5 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 OAJ24376.1 - 3.5e-20 72.3 1.9 5.6e-20 71.6 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 OAJ24376.1 - 4.4e-13 48.9 0.0 1.1e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein zf-U1 PF06220.7 OAJ24400.1 - 3.7e-05 23.2 0.0 5.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 U1 zinc finger BTB PF00651.26 OAJ24401.1 - 2.4e-12 46.7 0.1 1.4e-05 25.0 0.0 3.4 3 0 0 3 3 3 2 BTB/POZ domain 2OG-FeII_Oxy_3 PF13640.1 OAJ24402.1 - 2.9e-07 30.9 0.0 5.4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 OAJ24402.1 - 9.7e-06 25.1 0.0 9.2e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Vps5 PF09325.5 OAJ24403.1 - 1.3e-58 198.0 5.0 1.3e-58 198.0 3.5 3.6 3 1 1 4 4 4 1 Vps5 C terminal like RmlD_sub_bind PF04321.12 OAJ24403.1 - 7.7e-48 162.8 0.0 7.7e-48 162.8 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.16 OAJ24403.1 - 5.6e-23 81.6 0.0 1.4e-22 80.2 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PX PF00787.19 OAJ24403.1 - 5.1e-22 77.7 0.0 1.9e-21 75.9 0.0 2.0 1 0 0 1 1 1 1 PX domain NAD_binding_4 PF07993.7 OAJ24403.1 - 2.7e-07 29.7 0.1 1e-05 24.6 0.0 2.9 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 OAJ24403.1 - 9.3e-06 24.7 0.2 0.0002 20.3 0.1 2.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein MIP-T3 PF10243.4 OAJ24403.1 - 6.1 5.1 102.9 0.012 14.1 36.9 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Pep3_Vps18 PF05131.9 OAJ24427.1 - 1.3e-43 147.9 0.0 8.4e-43 145.3 0.0 2.2 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 OAJ24427.1 - 7.2e-08 32.1 9.4 5.3e-07 29.3 0.4 2.8 2 1 0 2 2 2 2 Region in Clathrin and VPS zf-RING_5 PF14634.1 OAJ24427.1 - 0.0017 18.0 1.0 0.0041 16.8 0.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 OAJ24427.1 - 0.028 14.2 4.9 0.023 14.5 1.7 2.1 2 0 0 2 2 2 0 Ring finger domain Vps39_2 PF10367.4 OAJ24427.1 - 0.039 14.1 0.4 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Terminase_5 PF06056.7 OAJ24427.1 - 0.11 12.0 3.1 0.067 12.7 0.3 2.0 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) DUF2175 PF09943.4 OAJ24427.1 - 0.2 11.7 0.0 0.2 11.7 0.0 3.0 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2175) TPR_11 PF13414.1 OAJ24427.1 - 1.9 8.1 4.5 8 6.1 0.0 3.5 3 1 1 4 4 4 0 TPR repeat DNA_pol_phi PF04931.8 OAJ24428.1 - 0.034 11.9 18.4 0.048 11.4 12.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF1822 PF08852.6 OAJ24428.1 - 0.038 12.8 0.0 0.038 12.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1822) Daxx PF03344.10 OAJ24428.1 - 0.12 10.8 24.4 0.16 10.4 16.9 1.1 1 0 0 1 1 1 0 Daxx Family BSP_II PF05432.6 OAJ24428.1 - 0.18 11.0 18.8 0.3 10.3 13.0 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Borrelia_P83 PF05262.6 OAJ24428.1 - 0.49 8.5 19.8 0.55 8.4 13.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein MIP-T3 PF10243.4 OAJ24428.1 - 0.83 8.0 36.1 1.1 7.6 25.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Raftlin PF15250.1 OAJ24428.1 - 0.85 8.0 11.9 0.56 8.6 7.0 1.5 1 1 0 1 1 1 0 Raftlin Nop53 PF07767.6 OAJ24428.1 - 0.88 8.4 38.1 1.4 7.8 26.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PPP4R2 PF09184.6 OAJ24428.1 - 2.4 7.6 24.3 4.5 6.7 16.9 1.4 1 0 0 1 1 1 0 PPP4R2 TEX19 PF15553.1 OAJ24428.1 - 2.6 7.9 7.9 17 5.2 5.0 2.2 2 0 0 2 2 2 0 Testis-expressed protein 19 PLRV_ORF5 PF01690.12 OAJ24428.1 - 3 6.8 14.9 4.3 6.3 10.3 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Sporozoite_P67 PF05642.6 OAJ24428.1 - 3.4 5.4 12.0 1.9 6.2 6.9 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 OAJ24428.1 - 6.2 6.3 24.0 17 4.9 16.6 1.7 1 0 0 1 1 1 0 Nucleoplasmin Pox_RNA_Pol_19 PF05320.7 OAJ24428.1 - 7.3 6.3 17.7 9.5 5.9 11.8 1.5 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Borrelia_P83 PF05262.6 OAJ24429.1 - 0.012 13.9 3.1 0.014 13.6 2.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC37_N PF03234.9 OAJ24429.1 - 0.032 14.5 3.2 0.064 13.5 2.2 1.5 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF3450 PF11932.3 OAJ24429.1 - 0.057 12.6 4.8 0.091 12.0 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Uds1 PF15456.1 OAJ24429.1 - 0.061 13.3 5.0 0.1 12.5 3.5 1.4 1 0 0 1 1 1 0 Up-regulated During Septation V_ATPase_I PF01496.14 OAJ24429.1 - 0.15 9.9 0.4 0.19 9.5 0.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 OAJ24429.1 - 0.15 11.7 2.1 0.27 10.9 1.4 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 PA26 PF04636.8 OAJ24429.1 - 0.15 10.6 0.4 0.22 10.1 0.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) HAUS6_N PF14661.1 OAJ24429.1 - 0.32 10.3 3.6 0.49 9.6 2.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus APG6 PF04111.7 OAJ24429.1 - 0.96 8.4 6.9 1.4 7.8 4.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 OAJ24429.1 - 1.2 9.1 9.7 2.8 8.0 6.7 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Med21 PF11221.3 OAJ24429.1 - 1.6 8.7 10.3 2.7 7.9 7.1 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Bap31 PF05529.7 OAJ24429.1 - 2.3 7.6 8.6 3.7 6.9 6.0 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Ribosomal_L7Ae PF01248.21 OAJ24447.1 - 6.6e-22 76.8 0.1 1.5e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 OAJ24447.1 - 0.0023 17.7 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 Daxx PF03344.10 OAJ24447.1 - 0.41 9.0 14.7 0.52 8.7 10.2 1.1 1 0 0 1 1 1 0 Daxx Family Utp14 PF04615.8 OAJ24447.1 - 1.7 6.7 24.0 2 6.4 16.6 1.1 1 0 0 1 1 1 0 Utp14 protein APC_CDC26 PF10471.4 OAJ24447.1 - 6.3 7.6 8.5 2.4 8.9 0.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 rve PF00665.21 OAJ24448.1 - 1.3e-05 25.2 0.1 3e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain MutS_V PF00488.16 OAJ24449.1 - 7.3e-79 264.4 0.3 1.3e-78 263.6 0.1 1.6 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 OAJ24449.1 - 1.3e-42 145.8 0.4 1.3e-42 145.8 0.3 2.1 3 0 0 3 3 3 1 MutS domain III MutS_I PF01624.15 OAJ24449.1 - 2.6e-22 78.9 3.8 1.2e-15 57.5 0.2 3.1 2 1 1 3 3 3 2 MutS domain I zf-C2H2_3 PF13878.1 OAJ24449.1 - 1.7e-12 46.6 2.0 3.7e-12 45.6 1.4 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO MutS_II PF05188.12 OAJ24449.1 - 5.4e-12 45.9 0.2 1.7e-11 44.3 0.1 1.9 1 0 0 1 1 1 1 MutS domain II Acetyltransf_13 PF13880.1 OAJ24449.1 - 2.9e-10 39.7 0.0 1.2e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 ESCO1/2 acetyl-transferase MutS_IV PF05190.13 OAJ24449.1 - 2.7e-06 27.4 0.4 1.3e-05 25.3 0.1 2.2 2 0 0 2 2 2 1 MutS family domain IV Fe-S_biosyn PF01521.15 OAJ24450.1 - 1e-14 54.4 0.0 1.5e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SUI1 PF01253.17 OAJ24470.1 - 1.3e-31 108.1 1.1 1.7e-31 107.8 0.8 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 EB PF01683.13 OAJ24474.1 - 1.4 9.0 31.7 0.25 11.4 3.2 4.1 3 3 0 3 3 3 0 EB module DUF4231 PF14015.1 OAJ24475.1 - 0.0043 17.0 0.9 0.3 11.0 0.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4231) DUF2721 PF11026.3 OAJ24475.1 - 0.065 12.8 0.2 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF2207 PF09972.4 OAJ24475.1 - 0.29 9.6 4.4 1.1 7.7 0.0 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) zf-RING_2 PF13639.1 OAJ24498.1 - 1.2e-13 50.6 3.8 2.6e-13 49.5 2.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAJ24498.1 - 1.8e-13 50.3 0.7 3.1e-13 49.6 0.5 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 OAJ24498.1 - 7.9e-07 28.6 2.5 1.6e-06 27.6 1.7 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAJ24498.1 - 9.9e-07 28.5 0.8 1.9e-06 27.6 0.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 OAJ24498.1 - 7.2e-06 25.6 2.6 1.2e-05 24.9 1.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAJ24498.1 - 1.1e-05 25.0 4.6 4.3e-05 23.0 3.3 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ24498.1 - 1.5e-05 24.9 3.3 1.5e-05 24.9 2.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAJ24498.1 - 0.00012 21.7 2.6 0.00029 20.4 1.8 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 OAJ24498.1 - 0.0053 16.6 3.0 0.0089 15.8 1.6 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 OAJ24498.1 - 0.036 14.0 0.2 0.08 12.9 0.2 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain ORC6 PF05460.8 OAJ24498.1 - 0.62 9.1 1.1 1.4 7.9 0.7 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf-RING_4 PF14570.1 OAJ24498.1 - 2.1 7.9 4.0 1.3 8.6 1.4 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Glycophorin_A PF01102.13 OAJ24499.1 - 0.00041 20.0 0.2 0.00041 20.0 0.1 2.4 2 1 1 3 3 3 1 Glycophorin A Mucin PF01456.12 OAJ24499.1 - 0.013 15.3 13.1 0.013 15.3 9.1 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Syndecan PF01034.15 OAJ24499.1 - 0.034 13.8 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.1 OAJ24499.1 - 0.056 13.1 0.5 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family Plasmodium_Vir PF05795.6 OAJ24499.1 - 0.11 11.7 0.5 0.18 10.9 0.3 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SOG2 PF10428.4 OAJ24499.1 - 5.1 5.6 8.9 6.2 5.3 6.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein TMEM154 PF15102.1 OAJ24500.1 - 0.0022 17.6 1.1 0.0022 17.6 0.7 1.8 2 0 0 2 2 2 1 TMEM154 protein family DUF1191 PF06697.7 OAJ24500.1 - 0.035 12.9 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 OAJ24500.1 - 0.048 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 OAJ24500.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Mucin PF01456.12 OAJ24500.1 - 0.17 11.6 24.6 0.015 15.0 12.7 2.2 3 0 0 3 3 3 0 Mucin-like glycoprotein IncA PF04156.9 OAJ24500.1 - 2.3 7.7 3.8 0.45 10.0 0.2 1.6 2 0 0 2 2 2 0 IncA protein Dynamitin PF04912.9 OAJ24501.1 - 9.7e-14 50.9 0.0 6.3e-07 28.5 0.0 2.0 2 0 0 2 2 2 2 Dynamitin CAP_N PF01213.14 OAJ24502.1 - 2e-80 270.4 22.4 4.8e-79 265.8 15.5 3.1 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 OAJ24502.1 - 5.7e-52 175.2 3.6 7.3e-52 174.8 2.5 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 OAJ24502.1 - 0.004 16.5 0.8 0.0067 15.8 0.5 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF2360 PF10152.4 OAJ24502.1 - 0.018 15.3 0.7 0.018 15.3 0.5 2.6 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Mito_fiss_reg PF05308.6 OAJ24502.1 - 0.032 13.5 15.9 0.33 10.2 3.9 3.2 3 0 0 3 3 3 0 Mitochondrial fission regulator RdRP_1 PF00680.15 OAJ24502.1 - 0.18 9.9 0.0 0.27 9.4 0.0 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase NUDIX PF00293.23 OAJ24503.1 - 2.1e-20 72.7 0.0 3.2e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PG_binding_1 PF01471.13 OAJ24503.1 - 0.035 14.0 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Putative peptidoglycan binding domain NUDIX_2 PF13869.1 OAJ24503.1 - 0.038 13.3 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase SnoaL_2 PF12680.2 OAJ24522.1 - 0.00019 21.7 0.2 0.007 16.7 0.0 2.7 2 1 0 2 2 2 1 SnoaL-like domain zf-C2H2 PF00096.21 OAJ24523.1 - 1.1e-06 28.6 2.2 0.0067 16.7 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ24523.1 - 0.0013 18.9 2.2 0.12 12.7 0.0 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger Daxx PF03344.10 OAJ24523.1 - 0.0017 16.9 6.9 0.0017 16.9 4.8 3.5 3 1 1 4 4 4 1 Daxx Family eIF-3c_N PF05470.7 OAJ24523.1 - 2 6.4 2.6 3.6 5.5 1.8 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RRN3 PF05327.6 OAJ24523.1 - 2 6.4 5.6 3.5 5.6 3.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.7 OAJ24523.1 - 2.1 6.1 23.6 0.019 12.9 10.6 1.7 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.9 OAJ24523.1 - 8.9 4.2 22.0 0.06 11.3 7.7 2.1 2 0 0 2 2 2 0 CDC45-like protein Sod_Fe_C PF02777.13 OAJ24548.1 - 1.5e-14 53.6 0.0 5e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 OAJ24548.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Hemerythrin PF01814.18 OAJ24549.1 - 9.9e-11 41.9 4.8 1.6e-09 37.9 3.4 2.0 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain BTB PF00651.26 OAJ24550.1 - 6.2e-07 29.4 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF1768 PF08719.6 OAJ24552.1 - 5.6e-26 91.1 0.0 7.9e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) F-box-like PF12937.2 OAJ24574.1 - 8.4e-05 22.2 0.0 0.00023 20.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like DUF433 PF04255.9 OAJ24574.1 - 0.062 12.7 0.0 0.4 10.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF433) F-box-like PF12937.2 OAJ24575.1 - 0.029 14.0 1.6 0.035 13.8 0.1 1.9 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 OAJ24575.1 - 0.14 11.8 1.2 0.35 10.5 0.2 2.2 2 0 0 2 2 2 0 F-box domain RRF PF01765.14 OAJ24576.1 - 0.0022 17.4 0.0 0.0026 17.2 0.0 1.1 1 0 0 1 1 1 1 Ribosome recycling factor TRH PF05438.7 OAJ24576.1 - 0.027 13.8 0.1 0.028 13.7 0.0 1.1 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) TPR_12 PF13424.1 OAJ24577.1 - 0.06 13.2 0.5 0.83 9.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc5 PF12862.2 OAJ24577.1 - 0.088 12.6 0.0 0.31 10.8 0.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 Uds1 PF15456.1 OAJ24577.1 - 0.61 10.0 3.7 0.8 9.7 1.1 2.2 2 0 0 2 2 2 0 Up-regulated During Septation zf-CCHC PF00098.18 OAJ24601.1 - 0.051 13.5 0.6 0.14 12.1 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle HAD_2 PF13419.1 OAJ24603.1 - 1.8e-09 38.0 0.0 4.3e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAJ24603.1 - 8.7e-05 23.0 0.0 0.00028 21.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAJ24603.1 - 0.0082 16.3 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TRAUB PF08164.7 OAJ24604.1 - 1.1e-22 79.9 0.0 8.9e-22 77.0 0.0 2.6 1 1 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 OAJ24604.1 - 4e-09 36.7 5.7 1.3e-08 35.0 0.1 2.8 1 1 1 2 2 2 1 Apoptosis antagonizing transcription factor Daxx PF03344.10 OAJ24604.1 - 6.8 5.0 19.6 20 3.5 13.3 1.9 1 1 1 2 2 2 0 Daxx Family Pkinase PF00069.20 OAJ24605.1 - 9.4e-70 234.7 0.0 1.3e-69 234.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ24605.1 - 7.8e-35 120.1 0.0 1.1e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CDC27 PF09507.5 OAJ24605.1 - 0.00079 18.7 8.1 0.00079 18.7 5.6 2.4 2 0 0 2 2 2 1 DNA polymerase subunit Cdc27 Kinase-like PF14531.1 OAJ24605.1 - 0.02 13.8 0.0 0.072 12.0 0.0 1.7 2 0 0 2 2 2 0 Kinase-like MIP-T3 PF10243.4 OAJ24605.1 - 0.029 12.8 60.2 0.0028 16.1 13.0 2.7 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 OrfB_Zn_ribbon PF07282.6 OAJ24648.1 - 0.00013 21.5 1.4 0.091 12.4 0.1 2.5 2 0 0 2 2 2 2 Putative transposase DNA-binding domain IncFII_repA PF02387.10 OAJ24648.1 - 0.057 12.5 0.3 0.11 11.6 0.2 1.4 1 0 0 1 1 1 0 IncFII RepA protein family UMP1 PF05348.6 OAJ24649.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 DUF2457 PF10446.4 OAJ24650.1 - 5.7 5.5 27.3 0.024 13.3 11.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Dimer_Tnp_hAT PF05699.9 OAJ24651.1 - 6.3e-07 28.9 0.0 9.2e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Alpha-amylase PF00128.19 OAJ24677.1 - 9.2e-84 281.5 0.0 1.3e-83 281.0 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 OAJ24677.1 - 0.0041 16.0 0.1 0.0062 15.4 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme DUF2838 PF10998.3 OAJ24678.1 - 1.4e-37 127.9 9.6 3.7e-37 126.6 6.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) Cellulase PF00150.13 OAJ24679.1 - 2.6e-09 36.7 9.8 2.9e-09 36.5 6.2 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3357 PF11837.3 OAJ24679.1 - 0.032 14.0 1.3 0.066 13.0 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DPBB_1 PF03330.13 OAJ24705.1 - 2.4e-06 27.4 0.1 3.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Zip PF02535.17 OAJ24705.1 - 0.023 13.7 0.7 0.018 14.0 0.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Barwin PF00967.12 OAJ24705.1 - 0.028 14.0 0.2 0.064 12.9 0.1 1.6 1 1 0 1 1 1 0 Barwin family SelP_N PF04592.9 OAJ24705.1 - 0.35 10.2 8.3 0.48 9.7 5.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Abhydrolase_3 PF07859.8 OAJ24706.1 - 1.5e-38 132.5 0.0 1.2e-30 106.6 0.0 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold DUF2424 PF10340.4 OAJ24706.1 - 8.2e-11 41.1 0.0 2.6e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 OAJ24706.1 - 3.5e-05 23.6 0.0 8.1e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 OAJ24706.1 - 0.084 11.5 0.1 0.65 8.6 0.0 2.5 4 0 0 4 4 4 0 Carboxylesterase family Peptidase_S9 PF00326.16 OAJ24706.1 - 0.088 12.0 0.0 0.21 10.7 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family AXE1 PF05448.7 OAJ24706.1 - 0.19 10.1 0.0 0.37 9.2 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) CFEM PF05730.6 OAJ24724.1 - 4.9e-08 32.6 10.1 7.2e-08 32.1 7.0 1.2 1 0 0 1 1 1 1 CFEM domain Sperm_Ag_HE2 PF05324.8 OAJ24724.1 - 0.14 12.1 0.1 4 7.4 0.0 2.4 2 0 0 2 2 2 0 Sperm antigen HE2 TIL PF01826.12 OAJ24724.1 - 0.51 10.5 7.9 0.84 9.7 5.5 1.3 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain CFEM PF05730.6 OAJ24725.1 - 0.0032 17.2 10.6 0.024 14.4 3.0 2.3 2 0 0 2 2 2 2 CFEM domain CFEM PF05730.6 OAJ24726.1 - 9e-07 28.6 12.5 2.1e-06 27.4 8.6 1.7 1 1 0 1 1 1 1 CFEM domain Toxin_3 PF00537.13 OAJ24726.1 - 0.021 14.6 5.7 0.052 13.4 3.9 1.5 1 0 0 1 1 1 0 Scorpion toxin-like domain WD40 PF00400.27 OAJ24727.1 - 1.4e-13 50.1 14.8 8.8e-06 25.4 0.1 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ATP-synt_D PF01813.12 OAJ24728.1 - 1.6e-66 223.6 3.0 2.6e-66 222.9 2.0 1.3 1 0 0 1 1 1 1 ATP synthase subunit D Daxx PF03344.10 OAJ24728.1 - 0.031 12.7 17.9 0.044 12.2 12.4 1.1 1 0 0 1 1 1 0 Daxx Family DUF876 PF05936.7 OAJ24728.1 - 0.095 11.1 0.4 1.2 7.4 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF876) K_channel_TID PF07941.6 OAJ24728.1 - 0.26 11.5 12.4 0.75 10.0 8.6 1.8 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Nop14 PF04147.7 OAJ24728.1 - 0.55 8.0 16.3 0.29 8.9 9.8 1.7 2 0 0 2 2 2 0 Nop14-like family NOA36 PF06524.7 OAJ24728.1 - 9.7 5.3 8.3 15 4.7 5.8 1.3 1 0 0 1 1 1 0 NOA36 protein RRM_1 PF00076.17 OAJ24729.1 - 6.5e-13 48.1 0.0 1e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ24729.1 - 3.9e-09 36.3 0.0 6.3e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ24729.1 - 0.0021 17.8 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YqeY PF09424.5 OAJ24730.1 - 8.6e-24 84.0 1.0 1.1e-23 83.6 0.7 1.1 1 0 0 1 1 1 1 Yqey-like protein DUF3365 PF11845.3 OAJ24730.1 - 0.03 14.1 0.5 0.04 13.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) DUF4254 PF14063.1 OAJ24730.1 - 0.038 13.5 0.6 0.061 12.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) PAP_assoc PF03828.14 OAJ24754.1 - 8.4e-15 54.4 0.0 2.1e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 OAJ24754.1 - 1.8e-08 34.5 0.0 3.7e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DEAD PF00270.24 OAJ24755.1 - 4e-20 71.9 0.0 4.4e-14 52.3 0.0 3.5 3 0 0 3 3 3 3 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ24755.1 - 6.5e-05 22.7 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ24755.1 - 0.0005 19.9 0.3 0.0012 18.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ24756.1 - 4.3e-45 153.2 0.0 2e-44 151.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ24756.1 - 6.2e-24 83.6 0.0 3.5e-23 81.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 OAJ24756.1 - 0.0096 14.7 0.0 0.027 13.2 0.0 1.5 1 1 0 2 2 2 1 SNF2 family N-terminal domain YqgF PF14639.1 OAJ24756.1 - 0.24 10.9 3.0 7.1 6.1 0.2 3.0 2 1 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 MIF4G PF02854.14 OAJ24777.1 - 1.3e-54 184.8 0.8 2.2e-54 184.0 0.5 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 OAJ24777.1 - 4.8e-12 45.5 0.0 2e-11 43.6 0.0 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 THRAP3_BCLAF1 PF15440.1 OAJ24777.1 - 0.00025 19.8 36.7 0.00025 19.8 25.4 4.5 4 1 1 5 5 5 1 THRAP3/BCLAF1 family MIP-T3 PF10243.4 OAJ24777.1 - 0.00048 18.7 61.2 0.00048 18.7 42.4 4.5 4 1 0 5 5 5 1 Microtubule-binding protein MIP-T3 Y_phosphatase2 PF03162.8 OAJ24778.1 - 2.7e-50 169.9 0.0 3e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 OAJ24778.1 - 4.9e-05 23.6 0.0 0.0011 19.2 0.0 2.0 1 1 1 2 2 2 1 Tyrosine phosphatase family HTH_CodY PF08222.6 OAJ24778.1 - 0.13 11.6 0.0 0.55 9.6 0.0 2.0 2 1 0 2 2 2 0 CodY helix-turn-helix domain PseudoU_synth_2 PF00849.17 OAJ24779.1 - 9.3e-27 93.8 0.1 1.4e-26 93.2 0.1 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ribosomal_L22 PF00237.14 OAJ24801.1 - 1.9e-20 72.7 0.5 3.4e-20 71.9 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF2934 PF11154.3 OAJ24801.1 - 0.021 14.1 2.6 0.054 12.8 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) SIR2 PF02146.12 OAJ24802.1 - 7.5e-29 100.7 0.0 3.6e-17 62.6 0.0 2.1 2 0 0 2 2 2 2 Sir2 family ADH_zinc_N PF00107.21 OAJ24803.1 - 2e-27 95.2 0.1 3.2e-27 94.6 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ24803.1 - 7.9e-10 38.4 0.0 1.8e-08 34.1 0.0 2.4 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 OAJ24803.1 - 8.7e-10 39.5 0.0 2.2e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3317 PF11779.3 OAJ24804.1 - 3.4e-06 26.3 0.4 5.4e-06 25.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Epiglycanin_C PF14654.1 OAJ24804.1 - 0.052 13.5 0.2 0.081 12.9 0.1 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Myosin_N PF02736.14 OAJ24805.1 - 0.0017 17.9 4.0 0.0033 17.0 2.8 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF2945 PF11160.3 OAJ24805.1 - 0.057 13.2 2.1 0.086 12.6 1.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2945) 2OG-FeII_Oxy PF03171.15 OAJ24851.1 - 0.021 15.1 0.0 0.063 13.5 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Phage_integrase PF00589.17 OAJ24852.1 - 0.00034 20.3 0.0 0.00074 19.2 0.0 1.5 2 0 0 2 2 2 1 Phage integrase family Peroxin-3 PF04882.7 OAJ24853.1 - 1.2e-07 30.8 0.0 1.4e-05 23.9 0.0 2.3 2 1 0 2 2 2 2 Peroxin-3 DUF676 PF05057.9 OAJ24880.1 - 2.2e-29 102.3 0.0 4e-24 85.1 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 OAJ24880.1 - 0.0019 17.9 0.0 0.006 16.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ24880.1 - 0.038 13.8 1.6 0.69 9.7 1.1 2.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 OAJ24881.1 - 8.2e-27 93.9 0.0 1.6e-21 76.6 0.0 2.3 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 OAJ24881.1 - 0.00035 20.3 0.0 0.00064 19.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAJ24881.1 - 0.0025 17.4 0.1 0.0049 16.4 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 OAJ24881.1 - 0.004 17.0 0.5 0.0081 16.0 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Sarcoglycan_2 PF05510.8 OAJ24881.1 - 0.019 13.2 0.0 0.077 11.2 0.0 1.8 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon Lipase_3 PF01764.20 OAJ24881.1 - 0.057 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2235 PF09994.4 OAJ24881.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) SNF2_N PF00176.18 OAJ24882.1 - 7.7e-68 228.4 0.0 2.6e-66 223.4 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ24882.1 - 6.4e-17 61.1 0.0 4.6e-16 58.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 OAJ24882.1 - 2.7e-08 33.0 0.3 9.4e-07 27.9 0.0 2.8 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 OAJ24882.1 - 2.8e-06 27.2 0.0 1.7e-05 24.7 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit EXOSC1 PF10447.4 OAJ24899.1 - 9.6e-27 92.7 0.0 1.8e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 TFIIS_M PF07500.9 OAJ24900.1 - 2.1e-18 66.4 0.0 4e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 OAJ24900.1 - 6.1e-11 41.8 6.9 9.4e-11 41.2 4.8 1.3 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.8 OAJ24900.1 - 1e-07 32.4 0.0 2.1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 SPOC domain DUF2890 PF11081.3 OAJ24900.1 - 0.23 11.5 11.3 0.83 9.6 7.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) zf-RING_2 PF13639.1 OAJ24900.1 - 0.45 10.3 5.0 0.82 9.5 3.5 1.4 1 0 0 1 1 1 0 Ring finger domain PHD_2 PF13831.1 OAJ24900.1 - 0.78 9.0 1.6 1.3 8.4 1.1 1.4 1 0 0 1 1 1 0 PHD-finger HAP1_N PF04849.8 OAJ24901.1 - 0.015 14.2 16.5 0.021 13.7 6.5 2.3 2 0 0 2 2 2 0 HAP1 N-terminal conserved region CR6_interact PF10147.4 OAJ24901.1 - 0.06 12.6 4.7 0.06 12.6 2.4 1.6 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 CENP-F_leu_zip PF10473.4 OAJ24901.1 - 0.081 12.7 17.1 5.6 6.8 0.2 3.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 OAJ24901.1 - 0.099 11.8 10.3 0.84 8.7 4.3 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DivIVA PF05103.8 OAJ24901.1 - 0.28 11.2 14.0 2.5 8.1 0.0 3.7 2 1 1 3 3 3 0 DivIVA protein Phlebovirus_NSM PF07246.6 OAJ24901.1 - 0.48 9.5 6.9 1.2 8.1 2.8 2.2 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M HALZ PF02183.13 OAJ24901.1 - 2.5 7.9 10.7 4 7.2 0.1 4.9 6 0 0 6 6 6 0 Homeobox associated leucine zipper Spc7 PF08317.6 OAJ24901.1 - 3.6 6.1 12.3 0.51 8.9 0.2 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein WEMBL PF05701.6 OAJ24901.1 - 5.8 5.2 32.0 1.9 6.8 17.4 2.7 1 1 0 1 1 1 0 Weak chloroplast movement under blue light TMCO5 PF14992.1 OAJ24901.1 - 6.6 5.7 8.1 15 4.5 4.9 1.9 2 0 0 2 2 2 0 TMCO5 family Peptidase_C97 PF05903.9 OAJ24902.1 - 2.8e-15 56.4 0.0 1.7e-11 44.1 0.0 2.2 2 0 0 2 2 2 2 PPPDE putative peptidase domain ATP_bind_4 PF01902.12 OAJ24926.1 - 1.9e-40 138.5 0.0 5.6e-29 101.0 0.0 2.3 2 0 0 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 OAJ24926.1 - 1.9e-22 79.2 0.1 2.3e-15 56.4 0.1 2.5 2 0 0 2 2 2 2 Endoribonuclease L-PSP tRNA_Me_trans PF03054.11 OAJ24926.1 - 0.0086 14.6 0.0 0.013 14.1 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase VEFS-Box PF09733.4 OAJ24926.1 - 0.067 12.8 0.2 0.57 9.8 0.0 2.3 2 0 0 2 2 2 0 VEFS-Box of polycomb protein NMD3 PF04981.8 OAJ24927.1 - 5.3e-76 254.8 0.5 7.8e-76 254.2 0.4 1.3 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 OAJ24927.1 - 0.011 15.5 6.5 0.047 13.5 3.1 2.6 2 1 1 3 3 3 0 Double zinc ribbon Ribosomal_L37e PF01907.14 OAJ24927.1 - 1.4 8.8 3.5 17 5.2 0.1 2.7 2 0 0 2 2 2 0 Ribosomal protein L37e zf-dskA_traR PF01258.12 OAJ24927.1 - 6.8 6.5 6.6 0.68 9.7 0.0 2.6 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Complex1_LYR PF05347.10 OAJ24946.1 - 3.9e-08 32.9 0.2 7.3e-08 32.0 0.2 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAJ24946.1 - 1.7e-07 31.3 0.2 3.4e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 OAJ24946.1 - 2.3e-06 27.9 0.0 3.9e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 Complex1_LYR-like A_deamin PF02137.13 OAJ24947.1 - 1.5e-52 179.0 0.0 2e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Asp PF00026.18 OAJ24948.1 - 1.3e-31 109.9 0.1 1.7e-22 80.1 0.0 2.8 2 1 0 2 2 2 2 Eukaryotic aspartyl protease Ribosomal_L36e PF01158.13 OAJ24949.1 - 3.4e-37 126.3 6.3 4e-37 126.1 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF3140 PF11338.3 OAJ24949.1 - 0.086 12.9 0.5 0.14 12.3 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3140) CTP_transf_1 PF01148.15 OAJ24950.1 - 3.6e-67 226.7 26.9 3.5e-66 223.4 18.6 2.0 1 1 0 1 1 1 1 Cytidylyltransferase family LRR19-TM PF15176.1 OAJ24950.1 - 0.086 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain ATP-synt_B PF00430.13 OAJ24950.1 - 0.49 10.1 5.4 1.1 9.0 3.7 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF2433 PF10360.4 OAJ24978.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) Acyl_transf_1 PF00698.16 OAJ24979.1 - 7.9e-12 45.1 0.1 2.9e-06 26.8 0.0 3.0 1 1 1 2 2 2 2 Acyl transferase domain Hexapep PF00132.19 OAJ24980.1 - 1e-13 50.0 6.4 6.3e-11 41.2 3.0 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 OAJ24980.1 - 6.1e-13 48.0 7.1 1.4e-11 43.7 2.5 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 OAJ24980.1 - 3.6e-08 33.3 0.0 1e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep_2 PF14602.1 OAJ24981.1 - 1.4e-12 46.8 3.3 8.5e-11 41.2 1.2 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 OAJ24981.1 - 3e-12 45.4 2.0 4.6e-09 35.3 1.0 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 OAJ24981.1 - 9.3e-10 38.3 0.1 2.3e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Maltose acetyltransferase WW PF00397.21 OAJ25009.1 - 0.0025 17.6 4.5 0.013 15.3 3.1 2.0 1 1 0 1 1 1 1 WW domain ATG11 PF10377.4 OAJ25010.1 - 4.4e-24 84.8 0.0 9.9e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein 11 Baculo_PEP_C PF04513.7 OAJ25010.1 - 6.4 6.6 18.6 1 9.2 0.2 4.5 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus MFS_1_like PF12832.2 OAJ25011.1 - 6.6e-19 67.4 0.2 6.6e-19 67.4 0.2 2.2 2 0 0 2 2 2 1 MFS_1 like family ABC2_membrane PF01061.19 OAJ25030.1 - 5.6e-32 110.6 17.5 5.6e-32 110.6 12.1 1.9 3 0 0 3 3 1 1 ABC-2 type transporter ABC_tran PF00005.22 OAJ25030.1 - 3.9e-26 91.9 0.0 6.2e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 OAJ25030.1 - 2.7e-08 34.1 0.0 0.00028 20.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAJ25030.1 - 1.7e-06 27.5 0.0 8.2e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ25030.1 - 3.6e-05 23.8 0.3 7.9e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ25030.1 - 0.00028 21.0 0.0 0.00084 19.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ25030.1 - 0.00053 19.6 0.3 0.0022 17.7 0.2 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 OAJ25030.1 - 0.00097 18.6 0.2 0.003 17.0 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 OAJ25030.1 - 0.0013 17.9 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAJ25030.1 - 0.0023 18.7 0.0 0.0045 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 OAJ25030.1 - 0.0043 17.0 0.0 0.0075 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 OAJ25030.1 - 0.0043 16.7 0.0 0.0088 15.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain SbcCD_C PF13558.1 OAJ25030.1 - 0.0074 16.1 0.0 0.067 13.1 0.0 2.6 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 OAJ25030.1 - 0.02 14.1 0.0 0.044 13.0 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAJ25030.1 - 0.039 14.2 0.2 0.061 13.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 OAJ25030.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 OAJ25030.1 - 0.051 13.7 0.0 0.86 9.8 0.0 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 OAJ25030.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAJ25030.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 OAJ25030.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 OAJ25030.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.12 OAJ25030.1 - 0.19 11.0 0.3 1.2 8.4 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.1 OAJ25030.1 - 0.21 11.1 0.3 0.37 10.3 0.2 1.2 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 OAJ25030.1 - 0.37 10.4 0.0 0.67 9.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase hEGF PF12661.2 OAJ25030.1 - 4.8 7.4 7.9 24 5.3 2.2 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF Ribosomal_L19 PF01245.15 OAJ25031.1 - 2.4e-22 78.8 0.1 3.6e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 Not3 PF04065.10 OAJ25032.1 - 4.7e-95 317.2 18.7 4.7e-95 317.2 12.9 2.2 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 OAJ25032.1 - 9.3e-46 155.0 11.0 9.3e-46 155.0 7.6 2.9 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family RVT_1 PF00078.22 OAJ25056.1 - 8.5e-27 93.9 0.0 1.5e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIA PF03153.8 OAJ25056.1 - 6.4 6.5 16.5 12 5.6 11.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.5 OAJ25058.1 - 0.012 14.7 4.4 0.016 14.2 3.0 1.2 1 0 0 1 1 1 0 BUD22 RTC_insert PF05189.8 OAJ25058.1 - 0.019 14.9 0.2 0.039 13.9 0.1 1.5 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain DBD_Tnp_Hermes PF10683.4 OAJ25058.1 - 0.13 11.7 0.1 0.38 10.2 0.0 1.8 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain Transposase_21 PF02992.9 OAJ25083.1 - 2.9e-15 55.9 0.0 6.2e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 NAM-associated PF14303.1 OAJ25084.1 - 5.3 7.3 12.3 0.39 11.0 3.4 2.3 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Retrotrans_gag PF03732.12 OAJ25104.1 - 0.025 14.6 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein Pkinase PF00069.20 OAJ25105.1 - 1e-39 136.2 0.0 1.4e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ25105.1 - 7.2e-21 74.4 0.0 9.9e-21 73.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RTC4 PF14474.1 OAJ25105.1 - 0.002 18.0 0.0 0.0056 16.6 0.0 1.7 1 1 0 1 1 1 1 RTC4-like domain APH PF01636.18 OAJ25105.1 - 0.0021 17.8 0.0 0.0077 15.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 OAJ25105.1 - 0.019 13.8 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 OAJ25105.1 - 0.18 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dimer_Tnp_hAT PF05699.9 OAJ25106.1 - 2.7e-14 52.5 0.0 6.3e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Nop14 PF04147.7 OAJ25106.1 - 0.0012 16.8 20.0 0.0012 16.8 13.8 1.8 2 0 0 2 2 2 1 Nop14-like family CKAP2_C PF15297.1 OAJ25106.1 - 0.21 10.3 4.9 6 5.5 0.0 2.4 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus Lin-8 PF03353.10 OAJ25106.1 - 0.7 9.1 6.4 1.4 8.1 4.4 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Herpes_TAF50 PF03326.8 OAJ25106.1 - 1.2 8.0 6.3 2.1 7.1 4.4 1.3 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) YL1 PF05764.8 OAJ25106.1 - 1.3 8.5 27.1 0.034 13.7 14.1 1.8 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.9 OAJ25106.1 - 2.2 6.2 15.6 4.2 5.2 10.8 1.4 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 OAJ25106.1 - 2.2 8.1 21.5 0.21 11.4 10.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LRR_4 PF12799.2 OAJ25134.1 - 2e-32 110.2 25.1 1.1e-06 28.0 0.9 8.0 6 2 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ25134.1 - 2.2e-22 78.5 24.2 3.6e-09 36.2 1.4 5.8 4 1 0 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 OAJ25134.1 - 8.9e-13 46.3 34.1 0.26 11.4 0.4 10.9 10 1 1 11 11 11 6 Leucine Rich Repeat LRR_6 PF13516.1 OAJ25134.1 - 1.6e-06 27.5 21.3 2.5 8.4 0.1 9.0 9 1 1 10 10 10 3 Leucine Rich repeat LRR_7 PF13504.1 OAJ25134.1 - 3.3e-05 23.3 39.6 0.92 9.9 0.1 10.9 12 0 0 12 12 12 4 Leucine rich repeat LRR_9 PF14580.1 OAJ25134.1 - 7.9e-05 22.2 12.2 0.014 14.9 0.2 4.6 3 1 0 4 4 4 2 Leucine-rich repeat JAB PF01398.16 OAJ25135.1 - 1.4e-14 53.8 0.0 3.5e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 OAJ25135.1 - 4.7e-07 29.3 0.3 1.2e-06 27.9 0.2 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain NPL4 PF05021.10 OAJ25135.1 - 0.22 10.6 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 NPL4 family DnaJ PF00226.26 OAJ25136.1 - 1e-13 50.8 0.1 7.2e-13 48.0 0.0 2.4 2 1 0 2 2 2 1 DnaJ domain zf-CSL PF05207.8 OAJ25136.1 - 3.8e-09 35.9 0.7 3.8e-09 35.9 0.5 2.3 2 1 0 2 2 2 1 CSL zinc finger APH PF01636.18 OAJ25137.1 - 6.7e-11 42.3 0.1 9.9e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 OAJ25137.1 - 0.021 13.9 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF3673 PF12425.3 OAJ25137.1 - 0.025 14.4 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) Choline_kinase PF01633.15 OAJ25137.1 - 0.048 13.2 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase UDP-g_GGTase PF06427.6 OAJ25189.1 - 2.1e-53 180.7 0.0 3.7e-53 179.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 OAJ25189.1 - 5.4e-07 29.2 0.1 1.1e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 PspA_IM30 PF04012.7 OAJ25189.1 - 0.15 11.3 2.4 0.35 10.1 0.3 2.2 2 0 0 2 2 2 0 PspA/IM30 family NKWYS PF10364.4 OAJ25216.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein Transposase_21 PF02992.9 OAJ25217.1 - 0.066 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Transposase family tnp2 Mit_ribos_Mrp51 PF11709.3 OAJ25242.1 - 0.0011 18.2 0.5 1.5 7.9 0.0 3.1 2 1 0 2 2 2 2 Mitochondrial ribosomal protein subunit zf-Mss51 PF13824.1 OAJ25243.1 - 5e-21 74.2 2.1 1.1e-20 73.2 1.5 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Calreticulin PF00262.13 OAJ25245.1 - 5.4e-156 518.8 12.4 6.9e-156 518.4 8.6 1.1 1 0 0 1 1 1 1 Calreticulin family MtrD PF04207.7 OAJ25245.1 - 0.0027 17.1 2.6 0.0041 16.5 1.8 1.2 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit D DUF883 PF05957.8 OAJ25245.1 - 0.0063 16.8 2.9 0.0063 16.8 2.0 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) 2_5_RNA_ligase2 PF13563.1 OAJ25271.1 - 2.8e-18 66.0 1.9 1.1e-10 41.4 0.1 2.3 2 0 0 2 2 2 2 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 OAJ25271.1 - 6.4e-05 22.8 0.1 0.21 11.5 0.0 3.2 3 0 0 3 3 3 2 LigT like Phosphoesterase CPDase PF07823.6 OAJ25271.1 - 0.0039 16.7 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 2 Cyclic phosphodiesterase-like protein Med3 PF11593.3 OAJ25272.1 - 0.012 14.9 0.8 0.015 14.5 0.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Prefoldin PF02996.12 OAJ25272.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Prefoldin subunit TruB_N PF01509.13 OAJ25274.1 - 4.3e-37 127.5 0.0 6e-36 123.8 0.0 2.2 1 1 1 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) DUF4637 PF15470.1 OAJ25274.1 - 0.014 14.9 1.8 0.014 14.9 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) CENP-B_dimeris PF09026.5 OAJ25275.1 - 0.012 15.8 1.9 0.012 15.8 1.3 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MOR2-PAG1_N PF14222.1 OAJ25297.1 - 8.6e-114 381.2 0.0 1.5e-113 380.4 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 OAJ25297.1 - 2e-61 208.0 3.8 2e-61 208.0 2.7 3.1 3 1 1 4 4 4 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 OAJ25297.1 - 1.9e-20 72.1 1.2 7.4e-07 27.1 0.0 4.9 5 0 0 5 5 5 4 Cell morphogenesis central region Fungal_trans PF04082.13 OAJ25298.1 - 1.1e-28 99.9 0.0 2.2e-28 98.8 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ25298.1 - 2.5e-08 33.7 6.1 4.5e-08 32.8 4.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DDE_1 PF03184.14 OAJ25322.1 - 2e-30 105.5 0.0 3.9e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAJ25322.1 - 6.7e-09 35.4 0.0 3.1e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Mg_trans_NIPA PF05653.9 OAJ25323.1 - 3.8e-61 206.6 0.0 3.5e-56 190.3 0.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 OAJ25323.1 - 5.7e-08 32.9 8.7 2.4e-05 24.4 0.1 2.7 2 1 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 OAJ25323.1 - 0.0004 20.4 0.6 0.0004 20.4 0.4 3.1 3 1 0 3 3 3 1 EamA-like transporter family 7TMR-DISM_7TM PF07695.6 OAJ25323.1 - 0.023 14.3 4.3 0.056 13.1 3.0 1.6 1 0 0 1 1 1 0 7TM diverse intracellular signalling Pkinase PF00069.20 OAJ25324.1 - 2.5e-66 223.4 0.0 4.2e-66 222.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ25324.1 - 1.6e-34 119.1 0.0 1.4e-33 116.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ25324.1 - 1.3e-06 27.6 0.0 2.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.14 OAJ25324.1 - 0.00037 19.8 0.0 0.00061 19.1 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 RIO1 PF01163.17 OAJ25324.1 - 0.039 13.2 0.1 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pyrid_oxidase_2 PF13883.1 OAJ25349.1 - 5.3e-25 88.1 0.0 7.2e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Kelch_2 PF07646.10 OAJ25349.1 - 0.037 13.7 0.8 1.5 8.7 0.3 2.9 2 1 0 2 2 2 0 Kelch motif ATP-synt_J PF04911.7 OAJ25349.1 - 0.069 12.6 0.6 0.33 10.4 0.0 2.3 2 1 0 2 2 2 0 ATP synthase j chain GDI PF00996.13 OAJ25350.1 - 8.5e-195 647.1 0.0 1e-194 646.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 OAJ25350.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Amidase PF01425.16 OAJ25351.1 - 7.1e-94 315.1 0.9 1.1e-93 314.5 0.6 1.2 1 0 0 1 1 1 1 Amidase ECH PF00378.15 OAJ25352.1 - 3.3e-51 173.7 0.0 4.7e-45 153.6 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 OAJ25352.1 - 0.0095 16.0 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region DUF755 PF05501.6 OAJ25352.1 - 1.8 8.6 7.9 3.1 7.8 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) PAT1 PF09770.4 OAJ25381.1 - 9.3 4.3 39.6 0.025 12.8 1.9 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Cupin_1 PF00190.17 OAJ25382.1 - 3.3e-29 101.1 0.0 4.2e-15 55.4 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 OAJ25382.1 - 3.2e-26 90.6 0.5 7.6e-14 50.9 0.0 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 OAJ25382.1 - 3.7e-10 39.6 0.4 2.5e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 OAJ25382.1 - 1.9e-07 30.3 0.0 0.013 14.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 OAJ25382.1 - 0.00085 18.9 0.3 0.012 15.2 0.1 2.4 1 1 0 2 2 2 1 Cupin MannoseP_isomer PF01050.13 OAJ25382.1 - 0.00087 18.9 0.0 0.45 10.1 0.0 2.3 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase Cupin_7 PF12973.2 OAJ25382.1 - 0.0093 15.7 0.2 0.95 9.3 0.0 2.7 2 1 0 2 2 2 1 ChrR Cupin-like domain ARD PF03079.9 OAJ25382.1 - 0.015 15.2 0.0 0.33 10.8 0.0 2.4 2 0 0 2 2 2 0 ARD/ARD' family 3-HAO PF06052.7 OAJ25382.1 - 0.016 14.6 0.0 3.9 6.8 0.0 2.4 2 1 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase GPI PF06560.6 OAJ25382.1 - 0.1 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Sugar_tr PF00083.19 OAJ25383.1 - 4.8e-118 394.5 20.5 5.9e-117 391.0 14.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ25383.1 - 2.3e-19 69.3 41.2 3e-14 52.4 12.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily YqhR PF11085.3 OAJ25383.1 - 0.00071 19.1 1.5 0.15 11.5 0.3 2.7 2 0 0 2 2 2 2 Conserved membrane protein YqhR DUF1229 PF06797.6 OAJ25383.1 - 0.054 12.3 4.8 4.6 5.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1229) DUF441 PF04284.8 OAJ25383.1 - 1.5 8.6 8.6 0.54 10.1 3.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF441) DUF1049 PF06305.6 OAJ25383.1 - 6.8 6.2 8.3 8.7 5.8 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) 4HBT_3 PF13622.1 OAJ25384.1 - 1.2e-31 110.3 1.5 1.7e-31 109.9 1.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 OAJ25384.1 - 4.8e-06 26.2 0.0 9.5e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA thioesterase Alk_phosphatase PF00245.15 OAJ25418.1 - 5.2e-08 32.0 0.0 7.2e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Peptidase_M20 PF01546.23 OAJ25419.1 - 4.6e-29 101.2 0.0 7.9e-29 100.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 OAJ25419.1 - 8.1e-15 54.5 0.0 1.3e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Coatomer_WDAD PF04053.9 OAJ25420.1 - 1.2e-139 465.9 0.0 2e-139 465.2 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 OAJ25420.1 - 2.6e-78 263.4 0.0 3.9e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 OAJ25420.1 - 3.2e-51 169.4 10.1 4.4e-11 42.2 0.0 8.1 9 0 0 9 9 9 6 WD domain, G-beta repeat Clathrin PF00637.15 OAJ25420.1 - 0.011 15.3 0.1 0.026 14.1 0.1 1.6 1 0 0 1 1 1 0 Region in Clathrin and VPS Nup160 PF11715.3 OAJ25420.1 - 0.018 13.2 5.3 0.12 10.4 0.1 3.0 1 1 2 3 3 3 0 Nucleoporin Nup120/160 TPR_2 PF07719.12 OAJ25420.1 - 0.092 12.7 0.1 12 6.1 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Neur_chan_memb PF02932.11 OAJ25421.1 - 1.6 8.5 4.6 2.5 7.9 3.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DNA_pol_viral_N PF00242.12 OAJ25421.1 - 6.5 5.6 15.2 12 4.8 10.5 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Peptidase_M24 PF00557.19 OAJ25422.1 - 5.2e-43 147.0 0.1 6.5e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Med26 PF08711.6 OAJ25423.1 - 1.4e-05 24.4 0.0 2.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain HAT PF02184.11 OAJ25423.1 - 0.051 13.3 0.2 0.094 12.4 0.1 1.4 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat DNA_Packaging PF11053.3 OAJ25423.1 - 0.06 12.9 0.2 0.082 12.5 0.2 1.2 1 0 0 1 1 1 0 Terminase DNA packaging enzyme CBF_beta PF02312.12 OAJ25424.1 - 0.14 11.7 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 Core binding factor beta subunit CAF1 PF04857.15 OAJ25425.1 - 2.1e-64 217.3 0.0 3.1e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease VWA_2 PF13519.1 OAJ25427.1 - 1.1e-09 38.6 0.1 1.1e-09 38.6 0.1 1.7 2 1 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.9 OAJ25427.1 - 0.00045 19.8 0.0 0.00066 19.3 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 OAJ25427.1 - 0.0033 16.8 11.9 0.086 12.4 1.1 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif Chorismate_bind PF00425.13 OAJ25427.1 - 0.062 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 chorismate binding enzyme TFIIE_beta PF02186.10 OAJ25454.1 - 0.00062 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 TFIIE beta subunit core domain RA PF00788.18 OAJ25455.1 - 2.2e-15 56.9 0.0 4.3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 OAJ25455.1 - 5.6e-14 51.2 0.4 1.7e-06 27.2 0.0 3.1 3 0 0 3 3 3 2 SH3 domain SAM_2 PF07647.12 OAJ25455.1 - 6e-10 38.8 0.0 9.3e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 OAJ25455.1 - 1.2e-09 37.5 1.8 2.5e-06 26.8 0.0 2.9 2 1 0 2 2 2 2 Variant SH3 domain SAM_1 PF00536.25 OAJ25455.1 - 2.6e-09 37.1 0.0 3.9e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 OAJ25455.1 - 1.1e-08 34.5 5.3 0.00033 20.1 0.1 2.8 3 0 0 3 3 3 2 Variant SH3 domain SAM_PNT PF02198.11 OAJ25455.1 - 0.26 11.0 0.0 1 9.1 0.0 1.8 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain RRM_1 PF00076.17 OAJ25456.1 - 4.7e-18 64.5 0.0 9.7e-17 60.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ25456.1 - 7.3e-13 48.3 0.0 5e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ25456.1 - 1.1e-11 44.4 0.0 1.5e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 OAJ25456.1 - 0.054 13.1 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 DbpA RNA binding domain OB_RNB PF08206.6 OAJ25456.1 - 0.11 12.0 0.2 0.39 10.2 0.2 1.8 1 1 0 1 1 1 0 Ribonuclease B OB domain RVT_1 PF00078.22 OAJ25457.1 - 1.5e-09 37.4 0.0 2.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSP70 PF00012.15 OAJ25458.1 - 5.4e-207 688.4 11.3 6.1e-207 688.2 7.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAJ25458.1 - 2.1e-17 62.7 0.1 3.4e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein DDR PF08841.5 OAJ25458.1 - 6.7e-05 21.8 1.2 0.0064 15.3 0.3 2.5 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 OAJ25458.1 - 0.012 15.1 0.0 0.043 13.4 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain RasGAP PF00616.14 OAJ25458.1 - 0.06 12.9 0.6 0.14 11.8 0.4 1.5 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Hydantoinase_A PF01968.13 OAJ25458.1 - 0.19 10.8 5.5 0.15 11.1 0.1 2.7 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase CENP-I PF07778.6 OAJ25458.1 - 0.29 9.2 2.8 2.2 6.3 0.6 2.1 2 0 0 2 2 2 0 Mis6 AAA_23 PF13476.1 OAJ25458.1 - 0.72 10.1 9.6 0.13 12.5 3.4 1.9 2 0 0 2 2 2 0 AAA domain Seryl_tRNA_N PF02403.17 OAJ25458.1 - 0.78 9.7 14.2 3.6 7.6 4.8 3.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Uds1 PF15456.1 OAJ25458.1 - 1.1 9.2 6.7 0.45 10.5 1.4 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Spectrin PF00435.16 OAJ25458.1 - 8 6.8 10.9 12 6.2 0.9 2.8 2 1 1 3 3 3 0 Spectrin repeat Phage_integrase PF00589.17 OAJ25492.1 - 3.9e-05 23.3 0.1 9e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 OAJ25492.1 - 0.077 12.3 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) HbrB PF08539.6 OAJ25494.1 - 5.6e-20 71.7 0.0 3e-08 33.6 0.0 3.3 3 0 0 3 3 3 3 HbrB-like Neur_chan_memb PF02932.11 OAJ25494.1 - 8.3 6.2 10.4 78 3.0 5.4 2.6 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SDA1 PF05285.7 OAJ25495.1 - 0.74 9.0 14.9 0.45 9.7 3.1 2.4 2 0 0 2 2 2 0 SDA1 RRM_1 PF00076.17 OAJ25522.1 - 1.1e-23 82.6 0.0 1.3e-11 43.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ25522.1 - 5e-19 68.0 0.0 3.2e-09 36.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 OAJ25522.1 - 1.2e-18 65.4 0.0 0.00015 21.0 0.0 5.6 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_5 PF13893.1 OAJ25522.1 - 7.1e-14 51.4 0.0 6.6e-08 32.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_21 PF13276.1 OAJ25522.1 - 0.15 12.0 0.1 0.39 10.7 0.1 1.6 1 0 0 1 1 1 0 HTH-like domain Nab6_mRNP_bdg PF10567.4 OAJ25522.1 - 0.24 10.3 0.0 0.63 8.9 0.0 1.6 2 0 0 2 2 2 0 RNA-recognition motif LIM_bind PF01803.11 OAJ25522.1 - 3.9 6.4 7.0 8.1 5.4 4.8 1.4 1 0 0 1 1 1 0 LIM-domain binding protein tRNA-synt_1g PF09334.6 OAJ25523.1 - 1.2e-91 307.2 0.4 4.8e-75 252.6 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 OAJ25523.1 - 7.8e-12 43.9 0.0 7.1e-05 21.0 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 OAJ25523.1 - 3.8e-06 26.2 0.4 0.017 14.2 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Acyl-CoA_dh_C PF12806.2 OAJ25523.1 - 0.15 11.9 1.3 0.32 10.8 0.9 1.5 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like TBX PF12598.3 OAJ25524.1 - 4.1 7.8 9.8 0.84 10.0 0.5 2.5 1 1 2 3 3 3 0 T-box transcription factor HLH PF00010.21 OAJ25525.1 - 4.4e-06 26.2 0.9 1.1e-05 25.0 0.6 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain ELL PF10390.4 OAJ25525.1 - 0.018 14.2 0.3 0.018 14.2 0.2 3.0 3 1 0 3 3 3 0 RNA polymerase II elongation factor ELL Nop14 PF04147.7 OAJ25525.1 - 0.039 11.8 17.0 0.077 10.9 3.9 2.1 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.7 OAJ25525.1 - 1.2 8.3 21.6 0.2 10.9 3.5 2.7 3 0 0 3 3 3 0 SDA1 Sigma70_ner PF04546.8 OAJ25525.1 - 1.9 8.0 14.0 2.7 7.5 1.2 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Ribosomal_L27 PF01016.14 OAJ25557.1 - 1.2e-34 117.9 0.2 2.1e-34 117.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein TRP PF06011.7 OAJ25558.1 - 3.2e-76 256.6 3.2 5.1e-76 256.0 2.2 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 OAJ25558.1 - 1.2e-28 99.9 0.0 1.6e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 OAJ25558.1 - 0.08 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 ML domain Abhydrolase_3 PF07859.8 OAJ25559.1 - 1.1e-32 113.3 0.0 1.4e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ25559.1 - 0.00054 19.7 0.0 0.00091 19.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 OAJ25559.1 - 0.0026 17.0 0.1 2 7.6 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family DUF2424 PF10340.4 OAJ25559.1 - 0.025 13.2 0.0 0.036 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Thioesterase PF00975.15 OAJ25559.1 - 0.12 12.5 0.1 0.24 11.6 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 OAJ25559.1 - 0.19 11.0 0.6 1.8 7.9 0.2 2.5 2 1 0 2 2 2 0 Putative esterase TFIIA PF03153.8 OAJ25560.1 - 2.6e-47 162.5 7.7 1.7e-27 97.2 3.9 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit PWWP PF00855.12 OAJ25561.1 - 5.4e-15 55.3 0.1 5.4e-15 55.3 0.1 2.3 2 1 0 2 2 2 1 PWWP domain YL1 PF05764.8 OAJ25561.1 - 0.0017 18.0 16.5 0.0022 17.6 11.4 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Daxx PF03344.10 OAJ25561.1 - 0.41 9.0 13.9 0.51 8.7 9.6 1.1 1 0 0 1 1 1 0 Daxx Family GAGA_bind PF06217.7 OAJ25561.1 - 1.6 8.6 7.8 2.1 8.2 5.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Hid1 PF12722.2 OAJ25561.1 - 2 5.9 8.8 2.5 5.6 6.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TATR PF03430.8 OAJ25561.1 - 2.1 6.8 6.1 2.5 6.6 4.3 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator RhoGEF PF00621.15 OAJ25585.1 - 4.7e-29 101.5 0.5 1.2e-28 100.1 0.3 1.6 1 0 0 1 1 1 1 RhoGEF domain SKN1 PF03935.10 OAJ25588.1 - 5.6e-174 579.0 0.7 6.5e-174 578.7 0.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 OAJ25588.1 - 1.6e-06 27.5 0.3 0.012 14.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Herpes_U59 PF04529.7 OAJ25617.1 - 0.087 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus U59 protein TPR_12 PF13424.1 OAJ25618.1 - 1e-05 25.3 0.6 0.084 12.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF494 PF04361.8 OAJ25618.1 - 0.015 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF494) Imm6 PF14434.1 OAJ25618.1 - 0.02 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Immunity protein Imm6 Apc5 PF12862.2 OAJ25618.1 - 0.048 13.5 0.3 8.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 Lon_C PF05362.8 OAJ25620.1 - 1.7e-05 24.2 0.0 1.7e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain GDH_N PF12466.3 OAJ25620.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal Rhodanese PF00581.15 OAJ25651.1 - 2e-12 47.4 0.0 5.8e-12 45.9 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain Nup188 PF10487.4 OAJ25652.1 - 0.00063 17.8 0.0 0.019 12.8 0.0 2.4 3 0 0 3 3 3 2 Nucleoporin subcomplex protein binding to Pom34 MFS_1 PF07690.11 OAJ25653.1 - 8.3e-30 103.6 24.3 8.3e-30 103.6 16.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ25653.1 - 5.5e-22 77.9 18.2 4.1e-19 68.4 4.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Myc_target_1 PF15179.1 OAJ25653.1 - 0.57 9.7 1.5 1.5 8.4 1.1 1.6 1 0 0 1 1 1 0 Myc target protein 1 SET PF00856.23 OAJ25675.1 - 5.3e-06 26.8 0.0 0.045 14.0 0.0 2.6 2 0 0 2 2 2 2 SET domain BSP_II PF05432.6 OAJ25676.1 - 0.21 10.8 4.4 7.6 5.7 4.0 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Peptidase_M16 PF00675.15 OAJ25677.1 - 3.6e-41 140.3 0.3 2.6e-40 137.5 0.0 2.6 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 OAJ25677.1 - 5.5e-36 123.9 0.3 2.3e-20 73.0 0.0 4.1 4 0 0 4 4 4 2 Peptidase M16 inactive domain Coagulin PF02035.10 OAJ25677.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Coagulin rve PF00665.21 OAJ25709.1 - 1.5e-15 57.3 0.0 5.1e-15 55.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ25709.1 - 4.8e-07 29.3 0.0 8.2e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ25710.1 - 1.6e-21 76.6 0.0 3e-20 72.5 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.1 OAJ25710.1 - 4.8e-11 42.3 0.0 6.2e-10 38.7 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAJ25710.1 - 4.9e-09 36.5 0.0 1.1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 OAJ25710.1 - 3.9e-05 23.2 0.1 7.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Phage_integrase PF00589.17 OAJ25710.1 - 5.7e-05 22.8 0.0 0.00015 21.5 0.0 1.7 1 0 0 1 1 1 1 Phage integrase family RVP PF00077.15 OAJ25710.1 - 0.0002 21.2 0.0 0.00049 19.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.5 OAJ25710.1 - 0.005 16.2 0.1 0.013 14.8 0.0 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 OAJ25710.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_IS240 PF13610.1 OAJ25710.1 - 0.039 13.9 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 DDE domain RVP_2 PF08284.6 OAJ25710.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Lact_bio_phlase PF09508.5 OAJ25744.1 - 0.023 12.3 0.0 0.033 11.8 0.0 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase SecY PF00344.15 OAJ25745.1 - 1.6e-98 329.8 8.1 1.9e-98 329.5 5.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 OAJ25745.1 - 3e-17 61.8 0.3 1.1e-16 60.0 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p Claudin_3 PF06653.6 OAJ25745.1 - 0.8 9.4 5.2 1.2 8.7 0.0 3.3 3 1 0 3 3 3 0 Tight junction protein, Claudin-like Histone PF00125.19 OAJ25746.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 PTPA PF03095.10 OAJ25747.1 - 4.6e-87 291.9 0.0 6e-87 291.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Bd3614-deam PF14439.1 OAJ25747.1 - 0.12 12.2 2.1 0.31 10.9 1.5 1.7 1 0 0 1 1 1 0 Bd3614-like deaminase DUF659 PF04937.10 OAJ25779.1 - 5.3e-05 22.7 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.9 OAJ25779.1 - 0.00029 20.4 0.0 0.00074 19.0 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ATP-grasp_4 PF13535.1 OAJ25780.1 - 8.4e-09 35.4 0.0 1.6e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain DHQ_synthase PF01761.15 OAJ25780.1 - 6.7e-05 21.9 0.0 0.00012 21.0 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase ATPgrasp_Ter PF15632.1 OAJ25780.1 - 0.0013 17.5 0.0 0.037 12.7 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon DUF4601 PF15373.1 OAJ25810.1 - 0.059 12.2 0.1 0.078 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) Ion_trans PF00520.26 OAJ25811.1 - 2.3e-06 26.9 8.6 9.8e-05 21.6 5.9 2.2 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 OAJ25811.1 - 0.00018 20.0 14.5 0.0038 15.7 4.1 2.3 3 0 0 3 3 3 2 Polycystin cation channel HALZ PF02183.13 OAJ25811.1 - 0.037 13.7 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Glyoxal_oxid_N PF07250.6 OAJ25812.1 - 5.6e-26 91.0 0.0 2.2e-23 82.5 0.0 3.7 3 1 0 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 OAJ25812.1 - 4.1e-20 71.7 0.2 8.2e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) SKG6 PF08693.5 OAJ25812.1 - 0.27 10.5 0.7 0.53 9.6 0.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Septin PF00735.13 OAJ25813.1 - 3e-06 26.4 0.3 3.3e-06 26.3 0.2 1.1 1 0 0 1 1 1 1 Septin Vps16_C PF04840.7 OAJ25814.1 - 1.6e-06 27.3 0.7 0.02 13.8 0.0 2.0 2 0 0 2 2 2 2 Vps16, C-terminal region K_channel_TID PF07941.6 OAJ25814.1 - 0.00024 21.2 11.2 0.00024 21.2 7.8 2.3 3 0 0 3 3 3 1 Potassium channel Kv1.4 tandem inactivation domain Retinal PF15449.1 OAJ25814.1 - 2.5 5.6 14.4 3.1 5.3 10.0 1.1 1 0 0 1 1 1 0 Retinal protein Ribosomal_60s PF00428.14 OAJ25814.1 - 5.7 7.4 12.0 0.76 10.2 5.0 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Orbi_NS3 PF01616.11 OAJ25817.1 - 0.33 9.8 1.2 0.78 8.6 0.1 2.0 2 0 0 2 2 2 0 Orbivirus NS3 Abhydrolase_9_N PF15420.1 OAJ25817.1 - 1.5 8.4 7.6 0.36 10.5 2.5 1.8 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus ANTH PF07651.11 OAJ25818.1 - 3.6e-48 163.7 0.0 4.7e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 OAJ25818.1 - 3e-05 23.8 0.0 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 ENTH domain PARG_cat PF05028.9 OAJ25818.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) 2OG-FeII_Oxy_3 PF13640.1 OAJ25846.1 - 0.00065 20.1 0.1 0.0014 19.1 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Med12 PF09497.5 OAJ25875.1 - 2.4e-23 81.8 0.0 6.1e-23 80.5 0.0 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 ARPC4 PF05856.7 OAJ25876.1 - 2.6e-76 254.7 3.5 2.8e-76 254.6 2.4 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) CBP4 PF07960.6 OAJ25877.1 - 1e-13 51.0 0.0 1.2e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.1 OAJ25877.1 - 0.00018 21.2 0.0 0.0002 21.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4574) DUF4414 PF14377.1 OAJ25877.1 - 0.088 12.7 0.2 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) DUF1206 PF06724.6 OAJ25877.1 - 0.11 12.2 0.5 0.22 11.2 0.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) HMG_CoA_synt_N PF01154.12 OAJ25878.1 - 8.9e-83 276.0 0.3 1.6e-82 275.2 0.1 1.5 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 OAJ25878.1 - 2.1e-82 276.7 0.0 2.7e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal Ribosomal_L1 PF00687.16 OAJ25878.1 - 0.026 13.8 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family Zn_protease PF05618.6 OAJ25879.1 - 0.0079 15.8 0.2 0.0091 15.6 0.1 1.1 1 0 0 1 1 1 1 Putative ATP-dependant zinc protease DUF3375 PF11855.3 OAJ25879.1 - 0.2 10.3 6.0 0.23 10.1 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) DUF3099 PF11298.3 OAJ25879.1 - 4.1 7.2 0.0 4.1 7.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) adh_short PF00106.20 OAJ25880.1 - 3e-09 37.0 0.0 3.8e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ25880.1 - 6e-05 22.7 0.0 7.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 KR domain PIF1 PF05970.9 OAJ25881.1 - 5.9e-21 74.8 0.1 2.3e-20 72.8 0.1 2.0 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ25881.1 - 6.4e-11 42.1 1.1 9.7e-10 38.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain Helitron_like_N PF14214.1 OAJ25881.1 - 1.2e-10 41.4 0.0 2.8e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAJ25881.1 - 4e-06 26.4 0.9 3e-05 23.6 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 OAJ25881.1 - 0.0023 17.9 0.0 0.0073 16.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ25881.1 - 0.02 15.0 0.0 0.056 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 OAJ25881.1 - 0.075 12.7 0.4 2.3 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF4171 PF13775.1 OAJ25882.1 - 0.11 12.7 0.1 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) Histone PF00125.19 OAJ25908.1 - 3.7e-27 94.2 0.6 5.8e-27 93.6 0.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ25908.1 - 8.7e-05 22.6 0.1 0.00014 21.9 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAJ25908.1 - 0.1 12.6 0.2 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone KAR9 PF08580.5 OAJ25909.1 - 0.13 10.4 3.3 0.13 10.5 2.3 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Macoilin PF09726.4 OAJ25909.1 - 0.54 8.4 3.0 0.62 8.2 2.1 1.1 1 0 0 1 1 1 0 Transmembrane protein BASP1 PF05466.7 OAJ25909.1 - 9.3 5.9 21.5 15 5.3 14.9 1.2 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) zf-BED PF02892.10 OAJ25910.1 - 0.00087 19.0 3.2 0.0018 17.9 2.2 1.5 1 0 0 1 1 1 1 BED zinc finger DUF2051 PF09738.4 OAJ25913.1 - 0.1 11.8 0.7 0.12 11.6 0.5 1.1 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) PS_Dcarbxylase PF02666.10 OAJ25937.1 - 1.2e-47 161.8 0.0 2.6e-47 160.7 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase C2 PF00168.25 OAJ25937.1 - 6.3e-29 99.6 0.0 2.5e-14 52.8 0.0 3.6 3 0 0 3 3 3 3 C2 domain SDA1 PF05285.7 OAJ25937.1 - 0.37 10.0 17.8 0.25 10.5 9.8 2.2 2 0 0 2 2 2 0 SDA1 Daxx PF03344.10 OAJ25937.1 - 1.8 6.9 17.9 0.021 13.3 6.5 1.9 2 0 0 2 2 2 0 Daxx Family TFIIA PF03153.8 OAJ25937.1 - 6.1 6.6 33.0 0.44 10.3 16.8 2.7 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DASH_Dam1 PF08653.5 OAJ25968.1 - 1.8e-20 72.4 0.5 3.5e-20 71.5 0.3 1.5 1 0 0 1 1 1 1 DASH complex subunit Dam1 Sen15 PF09631.5 OAJ25969.1 - 4.3e-12 46.1 0.0 2.3e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 Sen15 protein DUF2392 PF10288.4 OAJ25970.1 - 2e-15 57.0 0.0 3.3e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) MIP PF00230.15 OAJ25971.1 - 3.7e-36 124.7 11.9 4.9e-36 124.3 8.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein RCC1 PF00415.13 OAJ25972.1 - 1.4e-19 69.9 14.8 5.8e-05 23.2 0.0 7.0 5 2 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ25972.1 - 1.1e-18 66.3 24.2 7.4e-11 41.3 0.3 6.0 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Helicase_C_2 PF13307.1 OAJ25973.1 - 8.4e-37 126.6 0.0 1.2e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Helicase C-terminal domain NADH_dehy_S2_C PF06444.6 OAJ25973.1 - 0.2 12.0 1.8 0.5 10.7 0.0 2.3 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 C-terminus SE PF08491.5 OAJ26005.1 - 1.1e-80 270.4 0.0 6.2e-37 126.9 0.0 3.2 3 0 0 3 3 3 3 Squalene epoxidase DAO PF01266.19 OAJ26005.1 - 4.6e-13 48.8 2.2 4.2e-09 35.7 0.3 2.8 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAJ26005.1 - 6.9e-10 38.5 0.6 6.3e-06 25.4 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 OAJ26005.1 - 2.4e-07 30.8 0.0 3.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAJ26005.1 - 4.1e-05 23.5 0.9 0.0001 22.2 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 OAJ26005.1 - 0.00024 20.5 0.2 0.00053 19.4 0.2 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 OAJ26005.1 - 0.00029 20.5 0.1 0.0005 19.7 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 OAJ26005.1 - 0.00032 19.8 0.1 0.0005 19.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 OAJ26005.1 - 0.00061 18.7 0.8 0.00087 18.2 0.3 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 OAJ26005.1 - 0.00067 18.6 2.4 0.0022 16.9 1.1 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 OAJ26005.1 - 0.0011 18.0 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 OAJ26005.1 - 0.0019 17.9 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 OAJ26005.1 - 0.0019 18.5 0.4 0.0057 17.0 0.1 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 OAJ26005.1 - 0.0021 16.7 0.8 0.02 13.5 0.1 2.1 1 1 1 2 2 2 1 Tryptophan halogenase ThiF PF00899.16 OAJ26005.1 - 0.0054 16.5 0.1 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 OAJ26005.1 - 0.0085 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 OAJ26005.1 - 0.015 14.3 0.2 0.022 13.7 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Lycopene_cycl PF05834.7 OAJ26005.1 - 0.016 14.1 1.1 0.043 12.7 0.3 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein F420_oxidored PF03807.12 OAJ26005.1 - 0.084 13.3 0.1 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HI0933_like PF03486.9 OAJ26005.1 - 0.097 11.1 0.1 0.15 10.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_2 PF03446.10 OAJ26005.1 - 0.12 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GDI PF00996.13 OAJ26005.1 - 0.15 10.3 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Brix PF04427.13 OAJ26006.1 - 3.2e-48 163.9 0.0 4e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Brix domain PCI PF01399.22 OAJ26008.1 - 0.0009 19.5 0.0 0.0032 17.7 0.0 1.9 1 1 0 1 1 1 1 PCI domain DUF3767 PF12597.3 OAJ26009.1 - 2.9e-29 101.1 0.1 3.4e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) XRN_N PF03159.13 OAJ26010.1 - 1.7e-105 351.7 0.0 2.9e-105 350.8 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 OAJ26010.1 - 0.0013 18.5 2.8 0.0036 17.1 1.9 1.8 1 0 0 1 1 1 1 Zinc knuckle DUF2497 PF10691.4 OAJ26010.1 - 0.1 12.5 0.3 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) Pkinase PF00069.20 OAJ26012.1 - 1.9e-05 23.9 0.0 0.00024 20.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ26012.1 - 0.00027 20.1 0.1 0.067 12.2 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 OAJ26012.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ26012.1 - 0.011 15.5 0.1 0.026 14.2 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Na_Ca_ex PF01699.19 OAJ26045.1 - 4.6e-24 84.6 33.1 8e-13 48.1 8.8 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 OAJ26045.1 - 1.7e-14 53.9 4.3 1.7e-14 53.9 3.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF307) DEAD PF00270.24 OAJ26047.1 - 4.2e-46 156.5 0.0 7.8e-45 152.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ26047.1 - 5.6e-26 90.2 0.0 1.5e-25 88.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Phage_Gp23 PF10669.4 OAJ26047.1 - 0.033 14.3 0.1 0.033 14.3 0.1 3.2 2 1 1 3 3 3 0 Protein gp23 (Bacteriophage A118) Ctf8 PF09696.5 OAJ26048.1 - 0.00017 21.3 2.1 0.00041 20.1 1.4 1.8 1 1 0 1 1 1 1 Ctf8 CENP-T PF15511.1 OAJ26048.1 - 0.0046 16.2 5.2 0.005 16.1 3.6 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CDC45 PF02724.9 OAJ26048.1 - 0.0089 14.1 15.1 0.011 13.8 10.5 1.1 1 0 0 1 1 1 1 CDC45-like protein Daxx PF03344.10 OAJ26048.1 - 0.016 13.7 12.7 0.02 13.4 8.8 1.1 1 0 0 1 1 1 0 Daxx Family YL1 PF05764.8 OAJ26048.1 - 0.028 14.0 11.0 0.03 13.9 7.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CDC27 PF09507.5 OAJ26048.1 - 0.34 10.0 11.1 0.47 9.6 7.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.7 OAJ26048.1 - 0.89 7.4 21.7 1.1 7.0 15.0 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2890 PF11081.3 OAJ26048.1 - 0.96 9.4 4.0 1.3 9.0 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) NOA36 PF06524.7 OAJ26048.1 - 3.8 6.6 17.6 5.2 6.2 12.2 1.3 1 0 0 1 1 1 0 NOA36 protein eIF-3c_N PF05470.7 OAJ26048.1 - 3.9 5.4 7.2 4.4 5.2 5.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Pox_RNA_Pol_19 PF05320.7 OAJ26048.1 - 4.2 7.0 7.1 5.6 6.6 4.9 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF2457 PF10446.4 OAJ26048.1 - 5.8 5.5 32.3 7.5 5.1 22.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ebola_NP PF05505.7 OAJ26048.1 - 5.8 4.8 9.1 6.6 4.6 6.3 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DUF1510 PF07423.6 OAJ26048.1 - 6.5 6.0 14.8 8.5 5.6 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PPP4R2 PF09184.6 OAJ26048.1 - 7.3 6.0 16.2 9.5 5.6 11.3 1.2 1 0 0 1 1 1 0 PPP4R2 DUF2404 PF10296.4 OAJ26049.1 - 0.027 14.5 0.0 0.075 13.1 0.0 1.7 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) FAM176 PF14851.1 OAJ26049.1 - 4.9 6.8 7.8 8.1 6.1 0.2 2.3 2 0 0 2 2 2 0 FAM176 family TPR_11 PF13414.1 OAJ26050.1 - 2.3e-15 55.9 8.7 9.8e-05 21.9 0.3 7.1 6 0 0 6 6 6 3 TPR repeat TPR_2 PF07719.12 OAJ26050.1 - 5.1e-11 41.6 18.2 0.2 11.6 0.0 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ26050.1 - 1.8e-10 41.1 27.9 0.0016 19.0 0.0 7.7 8 1 0 8 8 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ26050.1 - 2.8e-10 40.0 24.1 2.6e-05 24.0 1.4 7.4 5 2 3 8 8 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ26050.1 - 1.3e-08 34.1 9.6 0.29 10.8 0.3 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ26050.1 - 1.6e-08 34.3 28.3 0.27 11.9 0.5 11.3 8 2 3 11 11 11 3 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ26050.1 - 5.1e-07 29.0 3.7 0.42 10.5 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ26050.1 - 1.1e-06 28.8 12.0 3.1e-05 24.2 0.8 6.2 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ26050.1 - 7.7e-06 25.3 10.4 5.6 7.0 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ26050.1 - 8.1e-06 25.9 16.0 0.47 11.0 0.2 9.5 10 0 0 10 10 9 1 Tetratricopeptide repeat BTAD PF03704.12 OAJ26050.1 - 5.3e-05 23.5 8.3 0.049 13.9 0.2 3.6 2 1 0 2 2 2 2 Bacterial transcriptional activator domain TPR_9 PF13371.1 OAJ26050.1 - 0.00028 20.6 14.2 0.23 11.3 1.0 6.3 3 2 3 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ26050.1 - 0.00034 20.6 13.9 0.0021 18.1 0.6 5.3 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 OAJ26050.1 - 0.00072 19.4 10.1 0.48 10.4 0.3 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ26050.1 - 0.0024 17.9 0.9 6.7 7.1 0.0 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat PPR_3 PF13812.1 OAJ26050.1 - 0.026 14.7 0.1 0.94 9.9 0.0 3.5 2 0 0 2 2 2 0 Pentatricopeptide repeat domain ChAPs PF09295.5 OAJ26050.1 - 0.25 10.0 0.0 0.59 8.8 0.0 1.5 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.9 OAJ26050.1 - 0.53 10.8 13.4 0.93 10.1 0.1 6.0 6 0 0 6 6 3 0 Tetratricopeptide repeat HrpA_pilin PF09589.5 OAJ26051.1 - 0.0028 18.0 2.0 0.0039 17.6 0.8 1.7 1 1 0 1 1 1 1 HrpA pilus formation protein Barwin PF00967.12 OAJ26052.1 - 0.015 14.9 0.1 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Barwin family DPBB_1 PF03330.13 OAJ26052.1 - 0.028 14.4 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel RVT_3 PF13456.1 OAJ26078.1 - 0.0035 17.0 0.0 0.0076 16.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like RVT_1 PF00078.22 OAJ26078.1 - 0.023 14.0 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.17 OAJ26079.1 - 4.1e-05 23.3 0.0 9e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 OAJ26079.1 - 0.0076 16.3 0.0 0.027 14.6 0.0 1.9 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DUF3440 PF11922.3 OAJ26079.1 - 0.043 13.3 0.0 0.61 9.6 0.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF3440) Phage_int_SAM_4 PF13495.1 OAJ26079.1 - 0.086 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Lon_C PF05362.8 OAJ26080.1 - 7.8e-65 218.0 0.1 1.4e-64 217.2 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 OAJ26080.1 - 9.6e-23 80.8 0.0 2.4e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAJ26080.1 - 2.6e-09 36.9 0.0 1.9e-08 34.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 OAJ26080.1 - 5.5e-09 35.5 0.0 1.2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase LON PF02190.11 OAJ26080.1 - 1.7e-06 27.8 0.0 3.9e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA_16 PF13191.1 OAJ26080.1 - 5.1e-05 23.3 0.1 5.1e-05 23.3 0.1 2.7 2 2 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 OAJ26080.1 - 7.3e-05 23.5 0.0 0.00028 21.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ26080.1 - 0.00033 20.5 0.2 0.011 15.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 OAJ26080.1 - 0.00046 20.1 0.0 0.0022 17.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 OAJ26080.1 - 0.00058 20.0 0.2 0.012 15.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 OAJ26080.1 - 0.0053 17.0 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAJ26080.1 - 0.0097 15.3 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 OAJ26080.1 - 0.012 14.6 0.0 0.036 13.1 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 OAJ26080.1 - 0.015 14.4 0.1 0.041 13.0 0.0 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 OAJ26080.1 - 0.015 15.0 2.2 0.017 14.8 0.3 2.1 2 0 0 2 2 1 0 Part of AAA domain RNA_helicase PF00910.17 OAJ26080.1 - 0.022 14.9 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 OAJ26080.1 - 0.023 14.3 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_PrkA PF08298.6 OAJ26080.1 - 0.035 12.8 0.0 0.62 8.6 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_14 PF13173.1 OAJ26080.1 - 0.05 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 OAJ26080.1 - 0.054 12.6 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.7 OAJ26080.1 - 0.065 12.8 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 OAJ26080.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 OAJ26080.1 - 0.17 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 OAJ26080.1 - 0.19 10.9 0.0 0.34 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 OAJ26080.1 - 0.75 10.0 0.0 0.75 10.0 0.0 2.5 2 1 0 3 3 2 0 AAA domain HEAT_2 PF13646.1 OAJ26081.1 - 0.072 13.3 1.0 0.2 11.9 0.7 1.7 1 0 0 1 1 1 0 HEAT repeats SQS_PSY PF00494.14 OAJ26113.1 - 3.7e-36 124.8 0.0 7.9e-36 123.7 0.0 1.6 1 0 0 1 1 1 1 Squalene/phytoene synthase Alk_phosphatase PF00245.15 OAJ26114.1 - 1.2e-71 241.6 0.3 1.5e-71 241.3 0.2 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Glutaredoxin PF00462.19 OAJ26115.1 - 1.2e-18 66.8 0.0 1.5e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 OAJ26115.1 - 0.00051 20.2 0.1 0.001 19.2 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.9 OAJ26115.1 - 0.00059 20.0 0.0 0.00078 19.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.1 OAJ26115.1 - 0.00086 19.4 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ26115.1 - 0.0021 17.9 0.0 0.003 17.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.1 OAJ26115.1 - 0.016 14.7 0.0 0.03 13.8 0.0 1.5 1 1 1 2 2 2 0 Thioredoxin TraF PF13728.1 OAJ26115.1 - 0.018 14.5 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Zn_ribbon_2 PF12674.2 OAJ26115.1 - 0.024 14.9 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative zinc ribbon domain Thioredoxin_7 PF13899.1 OAJ26115.1 - 0.03 14.3 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like DSBA PF01323.15 OAJ26115.1 - 0.058 12.9 0.1 0.29 10.6 0.1 1.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 OAJ26115.1 - 0.13 12.2 0.5 3.2 7.7 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin AAA PF00004.24 OAJ26116.1 - 5.1e-41 139.9 0.0 1.1e-40 138.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ26116.1 - 1.5e-05 25.1 0.0 0.0011 19.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAJ26116.1 - 1.7e-05 24.5 0.1 8.7e-05 22.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 OAJ26116.1 - 0.0002 21.3 0.0 0.00069 19.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 OAJ26116.1 - 0.00069 19.6 0.1 0.0025 17.8 0.0 1.8 2 1 0 2 2 1 1 AAA ATPase domain DUF815 PF05673.8 OAJ26116.1 - 0.002 17.0 0.0 0.0035 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 OAJ26116.1 - 0.0029 18.4 0.5 0.0076 17.0 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 OAJ26116.1 - 0.0056 16.4 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 OAJ26116.1 - 0.0086 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAJ26116.1 - 0.0089 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 OAJ26116.1 - 0.0091 15.1 0.0 0.021 13.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 OAJ26116.1 - 0.0094 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 OAJ26116.1 - 0.02 14.9 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 OAJ26116.1 - 0.023 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 OAJ26116.1 - 0.038 13.6 0.0 0.084 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 OAJ26116.1 - 0.041 14.1 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 OAJ26116.1 - 0.048 12.8 0.1 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 OAJ26116.1 - 0.049 13.5 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 OAJ26116.1 - 0.06 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Arch_ATPase PF01637.13 OAJ26116.1 - 0.12 12.0 0.1 19 4.8 0.0 2.5 2 1 1 3 3 2 0 Archaeal ATPase Sigma54_activat PF00158.21 OAJ26116.1 - 0.12 11.8 0.0 0.31 10.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 OAJ26116.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MSP1_C PF07462.6 OAJ26118.1 - 4 5.6 5.6 0.83 7.9 0.2 1.9 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus DUF221 PF02714.10 OAJ26119.1 - 6e-83 278.3 18.8 6.2e-83 278.3 12.4 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAJ26119.1 - 5e-35 120.3 1.0 5e-35 120.3 0.7 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 OAJ26119.1 - 4.1e-15 56.0 0.0 1e-14 54.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3318 PF11780.3 OAJ26120.1 - 0.051 13.1 0.7 0.11 12.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Pcc1 PF09341.5 OAJ26153.1 - 4.3e-20 71.5 0.9 5.1e-20 71.2 0.6 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF3323 PF11796.3 OAJ26156.1 - 0.00026 20.3 0.6 0.00026 20.3 0.4 2.2 2 0 0 2 2 2 1 Protein of unknown function N-terminus (DUF3323) Eclosion PF04736.7 OAJ26156.1 - 0.05 13.0 0.3 0.088 12.2 0.2 1.3 1 0 0 1 1 1 0 Eclosion hormone GATA PF00320.22 OAJ26157.1 - 3.3e-05 23.1 1.7 5.4e-05 22.4 1.2 1.4 1 0 0 1 1 1 1 GATA zinc finger Rod_cone_degen PF15201.1 OAJ26157.1 - 0.055 13.3 1.7 0.14 12.0 0.1 2.5 3 0 0 3 3 3 0 Progressive rod-cone degeneration T2SM PF04612.7 OAJ26157.1 - 1.1 9.0 5.9 0.55 10.0 2.2 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Gag_spuma PF03276.9 OAJ26157.1 - 4.1 5.6 12.8 5.9 5.1 8.9 1.3 1 0 0 1 1 1 0 Spumavirus gag protein MCPVI PF02993.9 OAJ26157.1 - 7.4 6.6 7.2 1.6 8.8 2.2 1.8 2 0 0 2 2 2 0 Minor capsid protein VI DUF3608 PF12257.3 OAJ26187.1 - 7.7e-68 228.4 0.0 8.6e-46 156.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3608) GST_N_3 PF13417.1 OAJ26188.1 - 0.00022 21.3 0.0 0.0016 18.5 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain DUF1365 PF07103.6 OAJ26189.1 - 1.4e-21 76.6 0.0 4.6e-20 71.7 0.0 3.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) HLH PF00010.21 OAJ26190.1 - 1.8e-16 59.5 0.2 4.9e-16 58.1 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_60s PF00428.14 OAJ26190.1 - 0.00068 19.9 3.9 0.00068 19.9 2.7 6.3 7 0 0 7 7 7 1 60s Acidic ribosomal protein ECH PF00378.15 OAJ26222.1 - 2.2e-35 121.9 0.0 3.4e-23 82.0 0.0 2.5 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase family AA_permease PF00324.16 OAJ26223.1 - 1.1e-130 436.2 38.6 1.3e-130 435.9 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAJ26223.1 - 2.7e-42 144.8 43.0 3.4e-42 144.4 29.8 1.1 1 0 0 1 1 1 1 Amino acid permease FHA PF00498.21 OAJ26224.1 - 1.3e-05 25.2 0.0 3.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain DUF3402 PF11882.3 OAJ26225.1 - 1.3e-130 436.1 0.0 4.1e-128 427.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.8 OAJ26225.1 - 1.1e-40 139.2 0.0 7.9e-37 126.6 0.0 2.6 2 1 0 2 2 2 2 N1221-like protein DPBB_1 PF03330.13 OAJ26227.1 - 0.0077 16.2 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ26227.1 - 0.022 14.4 0.2 0.038 13.6 0.1 1.4 1 0 0 1 1 1 0 Barwin family Trypan_PARP PF05887.6 OAJ26228.1 - 0.24 11.2 11.2 0.31 10.8 7.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) tRNA_bind PF01588.15 OAJ26259.1 - 2.3e-27 94.6 0.0 3.9e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.20 OAJ26259.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ26259.1 - 0.0083 15.9 0.1 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Menin PF05053.8 OAJ26259.1 - 2.2 6.3 5.1 0.87 7.6 1.3 1.9 2 0 0 2 2 2 0 Menin Aa_trans PF01490.13 OAJ26260.1 - 5.2e-07 28.5 0.3 0.00099 17.6 0.2 2.6 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein ABC_tran PF00005.22 OAJ26261.1 - 4.8e-37 127.3 1.4 1.1e-19 71.1 0.0 3.9 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 OAJ26261.1 - 2.2e-10 40.9 0.1 0.00011 22.2 0.0 4.2 4 0 0 4 4 4 1 AAA domain SMC_N PF02463.14 OAJ26261.1 - 1.2e-07 31.2 2.5 0.28 10.3 0.1 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_tran_2 PF12848.2 OAJ26261.1 - 2.8e-06 27.0 3.6 2.8e-06 27.0 2.5 2.5 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 OAJ26261.1 - 8.6e-06 25.1 0.2 0.019 14.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 OAJ26261.1 - 4.3e-05 23.3 0.0 0.002 18.0 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 OAJ26261.1 - 7.2e-05 22.0 0.5 0.0054 15.9 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 OAJ26261.1 - 0.00026 21.3 1.4 1.2 9.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 OAJ26261.1 - 0.0021 17.9 0.0 0.13 12.1 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 OAJ26261.1 - 0.0032 16.9 0.2 2.8 7.2 0.0 3.4 3 0 0 3 3 3 1 AAA-like domain ArgK PF03308.11 OAJ26261.1 - 0.0051 15.6 0.9 0.024 13.4 0.3 2.1 2 0 0 2 2 2 1 ArgK protein NACHT PF05729.7 OAJ26261.1 - 0.012 15.2 0.0 5.8 6.5 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 OAJ26261.1 - 0.037 14.1 0.3 2.2 8.4 0.0 3.4 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 OAJ26261.1 - 0.044 13.9 0.0 2.8 8.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 OAJ26261.1 - 0.074 12.7 0.6 14 5.3 0.0 3.8 5 0 0 5 5 5 0 AAA domain (dynein-related subfamily) DUF737 PF05300.6 OAJ26262.1 - 0.0028 17.6 10.0 0.0039 17.1 6.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF737) tRNA-synt_1e PF01406.14 OAJ26262.1 - 0.3 10.1 2.7 0.46 9.5 1.9 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain BTV_NS2 PF04514.7 OAJ26262.1 - 2.8 6.7 13.3 3.7 6.3 9.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Nup96 PF12110.3 OAJ26295.1 - 1.8e-83 279.9 0.1 2.6e-83 279.4 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 OAJ26295.1 - 2.5e-40 137.5 0.0 6.1e-40 136.2 0.0 1.7 1 1 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 OAJ26295.1 - 4.2e-30 104.3 285.7 5.3e-11 42.7 26.4 12.3 2 1 10 12 12 12 9 Nucleoporin FG repeat region RCC1 PF00415.13 OAJ26296.1 - 5.5e-48 160.9 8.5 5.6e-07 29.6 0.3 8.7 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ26296.1 - 8.4e-33 111.2 31.4 3e-06 26.7 0.5 8.5 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat Aldo_ket_red PF00248.16 OAJ26297.1 - 4.3e-48 163.5 0.0 5e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_C48 PF02902.14 OAJ26336.1 - 5.4e-09 35.9 0.1 1.4e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.4 OAJ26336.1 - 6.9e-08 32.5 0.1 7.6e-07 29.2 0.1 2.4 1 1 0 1 1 1 1 MULE transposase domain NA37 PF04245.8 OAJ26336.1 - 0.15 11.4 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein Spt5_N PF11942.3 OAJ26336.1 - 0.85 10.2 13.0 2 9.1 1.7 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal ADK PF00406.17 OAJ26338.1 - 2.1e-56 189.9 0.1 2.6e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 OAJ26338.1 - 1.9e-13 49.8 0.0 4.5e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid Zeta_toxin PF06414.7 OAJ26338.1 - 2.3e-05 23.5 0.0 3.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 OAJ26338.1 - 0.00067 19.5 0.0 0.0015 18.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ26338.1 - 0.034 14.9 0.0 0.047 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 OAJ26338.1 - 0.041 14.0 0.1 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 OAJ26338.1 - 0.084 13.1 0.1 0.21 11.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 OAJ26338.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain IncA PF04156.9 OAJ26339.1 - 0.002 17.7 0.3 0.0032 17.0 0.2 1.3 1 0 0 1 1 1 1 IncA protein Myosin_tail_1 PF01576.14 OAJ26339.1 - 0.0036 15.1 0.7 0.0051 14.6 0.5 1.1 1 0 0 1 1 1 1 Myosin tail Tropomyosin_1 PF12718.2 OAJ26339.1 - 0.014 15.2 0.1 0.022 14.5 0.1 1.2 1 0 0 1 1 1 0 Tropomyosin like DUF773 PF05600.7 OAJ26339.1 - 0.029 13.1 0.2 0.04 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF773) ADIP PF11559.3 OAJ26339.1 - 0.11 12.4 2.8 0.18 11.7 2.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 OAJ26339.1 - 0.19 12.0 1.0 0.36 11.1 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 OAJ26339.1 - 0.22 11.9 0.5 0.4 11.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) UQ_con PF00179.21 OAJ26340.1 - 1.2e-46 157.5 0.0 1.4e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ26340.1 - 2.8e-06 27.1 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 OAJ26340.1 - 0.049 13.5 2.5 0.11 12.4 1.7 1.8 1 1 0 1 1 1 0 RWD domain DUF3493 PF11998.3 OAJ26341.1 - 0.059 13.2 0.2 0.059 13.2 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) GATA PF00320.22 OAJ26342.1 - 1.5e-13 49.8 3.4 2.8e-13 48.9 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 OAJ26342.1 - 5e-07 29.4 0.0 5e-07 29.4 0.0 3.2 2 1 0 2 2 1 1 PAS fold PAS_3 PF08447.6 OAJ26342.1 - 7.4e-05 22.7 0.0 7.4e-05 22.7 0.0 2.3 2 1 0 2 2 1 1 PAS fold Mem_trans PF03547.13 OAJ26342.1 - 0.0008 17.8 0.4 0.00097 17.5 0.3 1.1 1 0 0 1 1 1 1 Membrane transport protein SAPS PF04499.10 OAJ26342.1 - 0.0013 17.4 16.3 0.0021 16.8 11.3 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Spore_coat_CotO PF14153.1 OAJ26342.1 - 0.0029 17.0 28.3 0.0049 16.3 19.6 1.3 1 0 0 1 1 1 1 Spore coat protein CotO PAS_4 PF08448.5 OAJ26342.1 - 0.012 15.6 0.0 0.012 15.6 0.0 2.4 2 0 0 2 2 1 0 PAS fold PAS_9 PF13426.1 OAJ26342.1 - 0.014 15.7 0.0 0.014 15.7 0.0 2.2 2 0 0 2 2 1 0 PAS domain Neur_chan_memb PF02932.11 OAJ26342.1 - 0.018 14.9 12.4 0.035 14.0 8.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TF_Zn_Ribbon PF08271.7 OAJ26342.1 - 0.044 13.0 0.3 0.21 10.9 0.0 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4045 PF13254.1 OAJ26342.1 - 0.052 12.8 18.1 0.1 11.8 12.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) HlyD_2 PF12700.2 OAJ26342.1 - 0.093 11.8 14.7 0.14 11.2 10.2 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Zip PF02535.17 OAJ26342.1 - 0.89 8.4 12.3 1.8 7.5 8.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 OAJ26342.1 - 2.9 5.8 20.9 4.3 5.2 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein LMBR1 PF04791.11 OAJ26342.1 - 3 6.3 6.6 4 5.8 4.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RR_TM4-6 PF06459.7 OAJ26342.1 - 3.3 7.5 22.7 6.8 6.5 15.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dimer_Tnp_hAT PF05699.9 OAJ26378.1 - 6.9e-08 32.0 0.1 1.6e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region Bud13 PF09736.4 OAJ26380.1 - 0.0029 17.8 16.3 0.003 17.8 11.3 1.1 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex Dynamin_N PF00350.18 OAJ26380.1 - 0.02 14.7 3.5 0.021 14.6 2.4 1.1 1 0 0 1 1 1 0 Dynamin family DUF4045 PF13254.1 OAJ26380.1 - 0.025 13.8 12.0 0.027 13.7 8.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) MIP-T3 PF10243.4 OAJ26380.1 - 0.046 12.1 23.8 0.048 12.1 16.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NARP1 PF12569.3 OAJ26380.1 - 0.049 12.3 18.9 0.054 12.2 13.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.9 OAJ26380.1 - 0.057 11.4 14.3 0.057 11.4 9.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 OAJ26380.1 - 0.064 10.9 13.3 0.064 10.9 9.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 OAJ26380.1 - 0.14 11.5 20.4 0.16 11.3 14.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Tim54 PF11711.3 OAJ26380.1 - 0.17 10.4 12.1 0.19 10.2 8.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Vfa1 PF08432.5 OAJ26380.1 - 0.19 11.7 17.5 0.23 11.4 12.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Med15 PF09606.5 OAJ26380.1 - 0.2 9.8 36.8 0.21 9.7 25.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_TAF50 PF03326.8 OAJ26380.1 - 0.21 10.4 17.9 0.21 10.4 12.4 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF4246 PF14033.1 OAJ26380.1 - 0.27 9.7 10.8 0.27 9.7 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) YqfQ PF14181.1 OAJ26380.1 - 0.33 10.9 17.5 0.42 10.6 12.1 1.2 1 0 0 1 1 1 0 YqfQ-like protein DDRGK PF09756.4 OAJ26380.1 - 0.34 10.3 29.0 0.42 9.9 20.1 1.1 1 0 0 1 1 1 0 DDRGK domain Hid1 PF12722.2 OAJ26380.1 - 0.35 8.5 14.4 0.38 8.3 10.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pox_Ag35 PF03286.9 OAJ26380.1 - 0.37 10.2 15.8 0.42 10.1 11.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CCDC71L PF15374.1 OAJ26380.1 - 0.4 9.9 16.0 0.48 9.7 11.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L TRAP_alpha PF03896.11 OAJ26380.1 - 0.52 9.2 6.7 0.6 9.0 4.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SAPS PF04499.10 OAJ26380.1 - 0.54 8.8 11.8 0.59 8.6 8.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF966 PF06136.8 OAJ26380.1 - 0.6 9.4 12.0 0.64 9.3 8.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4175 PF13779.1 OAJ26380.1 - 0.66 7.6 37.4 0.71 7.5 25.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Asp-B-Hydro_N PF05279.6 OAJ26380.1 - 0.71 9.6 15.6 0.83 9.4 10.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Spore_coat_CotO PF14153.1 OAJ26380.1 - 0.72 9.2 24.2 0.79 9.1 16.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO RR_TM4-6 PF06459.7 OAJ26380.1 - 0.93 9.3 21.2 1.2 9.0 14.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.8 OAJ26380.1 - 0.96 7.9 14.7 0.99 7.8 10.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BORG_CEP PF14957.1 OAJ26380.1 - 1 10.2 12.9 1.3 9.9 9.0 1.2 1 0 0 1 1 1 0 Cdc42 effector PIH1 PF08190.7 OAJ26380.1 - 1.2 8.4 18.1 1.3 8.4 12.5 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Gag_spuma PF03276.9 OAJ26380.1 - 1.3 7.3 25.1 1.4 7.1 17.4 1.2 1 0 0 1 1 1 0 Spumavirus gag protein AUX_IAA PF02309.11 OAJ26380.1 - 1.3 8.6 14.1 1.6 8.4 9.8 1.1 1 0 0 1 1 1 0 AUX/IAA family Hex_IIIa PF02455.11 OAJ26380.1 - 1.4 7.5 11.1 1.6 7.3 7.7 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) FLO_LFY PF01698.11 OAJ26380.1 - 1.4 7.6 15.8 1.6 7.4 11.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4407 PF14362.1 OAJ26380.1 - 1.5 7.7 18.8 1.7 7.5 13.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.3 OAJ26380.1 - 1.7 5.9 21.7 1.7 5.9 15.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FYDLN_acid PF09538.5 OAJ26380.1 - 1.7 9.2 13.0 2.4 8.7 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RP-C_C PF11800.3 OAJ26380.1 - 2.1 8.0 13.5 2.4 7.7 9.4 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region PAT1 PF09770.4 OAJ26380.1 - 2.1 6.4 32.0 2.1 6.4 22.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S21 PF00716.12 OAJ26380.1 - 2.5 7.3 8.2 2.8 7.1 5.7 1.0 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) UPF0560 PF10577.4 OAJ26380.1 - 2.5 6.2 17.6 2.7 6.1 12.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Med19 PF10278.4 OAJ26380.1 - 2.6 7.7 19.4 3.4 7.3 13.4 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 VID27 PF08553.5 OAJ26380.1 - 2.7 6.0 11.7 3.2 5.8 8.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein ATAD4 PF15321.1 OAJ26380.1 - 2.7 9.0 16.2 4.1 8.4 11.3 1.3 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 DUF3449 PF11931.3 OAJ26380.1 - 2.8 7.4 17.5 3.6 7.0 12.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) BSMAP PF12280.3 OAJ26380.1 - 2.9 7.7 12.0 3.4 7.5 8.3 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein FAM60A PF15396.1 OAJ26380.1 - 2.9 7.5 12.7 3.3 7.3 8.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Peptidase_S64 PF08192.6 OAJ26380.1 - 3 6.0 10.1 3.4 5.8 7.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 GAGA_bind PF06217.7 OAJ26380.1 - 3.4 7.5 16.0 3.9 7.3 11.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SLD3 PF08639.5 OAJ26380.1 - 3.5 6.1 19.9 4.3 5.8 13.8 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 Rtf2 PF04641.7 OAJ26380.1 - 3.7 6.6 19.0 4.4 6.4 13.2 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Borrelia_P83 PF05262.6 OAJ26380.1 - 3.9 5.6 19.6 4.1 5.5 13.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4557 PF15101.1 OAJ26380.1 - 4 7.2 20.7 5.3 6.8 14.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) G-7-MTase PF12803.2 OAJ26380.1 - 4.1 6.4 5.7 4.7 6.2 3.9 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Raftlin PF15250.1 OAJ26380.1 - 4.1 5.8 14.9 4.7 5.6 10.4 1.0 1 0 0 1 1 1 0 Raftlin Hom_end_hint PF05203.11 OAJ26380.1 - 4.9 6.8 10.5 5.9 6.5 7.3 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Cellulose_synt PF03552.9 OAJ26380.1 - 5 5.3 7.0 5.2 5.2 4.8 1.0 1 0 0 1 1 1 0 Cellulose synthase Gti1_Pac2 PF09729.4 OAJ26380.1 - 5.1 6.9 12.2 6.4 6.6 8.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family eIF-3_zeta PF05091.7 OAJ26380.1 - 5.3 5.5 20.0 6 5.3 13.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2201_N PF13203.1 OAJ26380.1 - 5.3 6.1 17.7 5.8 5.9 12.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF853 PF05872.7 OAJ26380.1 - 5.4 5.2 11.0 6 5.0 7.7 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) TAF4 PF05236.9 OAJ26380.1 - 5.6 6.1 24.1 6.7 5.9 16.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family RNase_H2-Ydr279 PF09468.5 OAJ26380.1 - 5.8 6.0 14.4 7.2 5.6 10.0 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) U79_P34 PF03064.11 OAJ26380.1 - 5.8 6.3 18.6 7.5 5.9 12.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 HSP70 PF00012.15 OAJ26380.1 - 5.9 4.6 13.0 6.5 4.5 9.0 1.0 1 0 0 1 1 1 0 Hsp70 protein Parvo_coat PF00740.13 OAJ26380.1 - 5.9 5.7 13.4 6.8 5.5 9.3 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF2828 PF11443.3 OAJ26380.1 - 6.1 4.9 13.2 6.8 4.7 9.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Band_3_cyto PF07565.8 OAJ26380.1 - 6.3 6.2 13.6 7.5 5.9 9.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2413 PF10310.4 OAJ26380.1 - 6.7 5.4 21.4 7.7 5.2 14.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Mem_trans PF03547.13 OAJ26380.1 - 7 4.8 7.1 7.2 4.7 4.9 1.0 1 0 0 1 1 1 0 Membrane transport protein AvrE PF11725.3 OAJ26380.1 - 7.5 3.4 16.3 8 3.3 11.3 1.0 1 0 0 1 1 1 0 Pathogenicity factor FHIPEP PF00771.15 OAJ26380.1 - 8.1 4.6 8.0 9.8 4.3 5.5 1.2 1 0 0 1 1 1 0 FHIPEP family CPSF100_C PF13299.1 OAJ26380.1 - 8.3 6.5 15.9 10 6.2 11.0 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Sporozoite_P67 PF05642.6 OAJ26380.1 - 9.4 3.9 10.1 10 3.8 7.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SOBP PF15279.1 OAJ26380.1 - 9.8 6.4 16.9 10 6.4 11.7 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein RCC1 PF00415.13 OAJ26417.1 - 4.5e-10 39.5 3.3 0.1 12.8 0.0 6.7 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ26417.1 - 0.00076 19.0 19.7 0.042 13.4 1.2 5.9 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat TRAPPC9-Trs120 PF08626.6 OAJ26418.1 - 6.2e-89 298.7 0.0 5.5e-74 249.2 0.0 3.5 3 1 0 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Ank PF00023.25 OAJ26419.1 - 6.4e-06 25.7 0.2 0.017 14.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 OAJ26419.1 - 9.7e-06 25.9 0.1 9.5e-05 22.8 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 OAJ26419.1 - 3.6e-05 24.0 0.1 0.0005 20.3 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 OAJ26419.1 - 0.0024 17.9 0.0 0.15 12.4 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat NUDIX PF00293.23 OAJ26420.1 - 3.7e-13 49.2 0.0 9.4e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain RVT_2 PF07727.9 OAJ26451.1 - 6e-82 274.3 0.0 8.8e-82 273.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ26451.1 - 8.7e-20 71.0 0.0 5.6e-19 68.4 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 OAJ26451.1 - 2.9e-12 46.1 0.0 5.3e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAJ26451.1 - 3.2e-10 39.4 0.1 9.8e-10 37.9 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 OAJ26451.1 - 9.5e-08 31.8 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ26451.1 - 6.5e-07 28.9 2.8 1.4e-06 27.9 2.0 1.6 1 0 0 1 1 1 1 Zinc knuckle UBN2_3 PF14244.1 OAJ26451.1 - 0.054 13.0 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type rve_3 PF13683.1 OAJ26451.1 - 0.058 12.9 0.0 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain zf-CCHC_4 PF14392.1 OAJ26451.1 - 0.21 11.2 6.0 0.039 13.6 1.1 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 OAJ26451.1 - 1.7 8.3 5.4 3.8 7.2 3.7 1.6 1 0 0 1 1 1 0 Zinc knuckle SAP18 PF06487.7 OAJ26453.1 - 1.3e-07 31.4 0.0 3.1e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) UPF0254 PF06787.6 OAJ26453.1 - 0.0053 16.2 0.3 0.0081 15.7 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0254) Ribosomal_60s PF00428.14 OAJ26453.1 - 0.62 10.5 18.4 0.44 10.9 1.6 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF2422 PF10337.4 OAJ26498.1 - 1.2e-63 215.5 2.2 3.8e-63 213.8 1.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 OAJ26498.1 - 1.6e-44 152.2 0.1 2.7e-44 151.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 OAJ26498.1 - 5.2e-05 23.1 27.1 0.0011 18.9 10.4 3.9 2 1 1 3 3 3 2 Fusaric acid resistance protein-like AATF-Che1 PF13339.1 OAJ26498.1 - 0.07 13.2 0.9 0.16 12.0 0.7 1.6 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor C2 PF00168.25 OAJ26499.1 - 4.4e-09 36.0 0.1 0.069 13.0 0.0 3.5 2 1 1 3 3 3 3 C2 domain DDE_Tnp_1_6 PF13751.1 OAJ26499.1 - 0.045 13.7 0.4 0.12 12.3 0.3 1.7 1 0 0 1 1 1 0 Transposase DDE domain Alginate_lyase PF05426.7 OAJ26501.1 - 1.8e-49 168.5 5.7 4.1e-48 164.0 1.1 2.3 2 0 0 2 2 2 2 Alginate lyase ETF PF01012.16 OAJ26502.1 - 3e-40 137.6 5.6 5.9e-40 136.6 3.9 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 OAJ26502.1 - 1.6e-35 120.5 1.8 2.4e-35 119.9 0.4 2.0 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain BMC PF00936.14 OAJ26502.1 - 0.0035 16.9 0.9 0.0035 16.9 0.6 2.6 2 0 0 2 2 2 1 BMC domain CRAL_TRIO_N PF03765.10 OAJ26504.1 - 1e-05 25.5 0.0 3.1e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.15 OAJ26504.1 - 0.0021 17.5 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2217 PF10265.4 OAJ26504.1 - 0.11 11.2 0.3 0.13 11.0 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) RNase_P_p30 PF01876.11 OAJ26505.1 - 3.8e-33 113.8 0.0 5.6e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 SAGA-Tad1 PF12767.2 OAJ26505.1 - 0.017 14.8 5.7 0.031 13.9 4.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Phage_integrase PF00589.17 OAJ26550.1 - 0.0061 16.2 0.0 0.038 13.6 0.0 2.2 2 1 0 2 2 2 1 Phage integrase family Amidase_2 PF01510.20 OAJ26551.1 - 0.025 14.6 0.0 0.072 13.1 0.0 1.7 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase RVT_3 PF13456.1 OAJ26552.1 - 0.00087 19.0 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like DUF2946 PF11162.3 OAJ26553.1 - 0.13 12.4 0.5 0.37 10.9 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) MutL_C PF08676.6 OAJ26587.1 - 8.3e-21 74.1 0.1 3.2e-20 72.1 0.0 2.0 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 OAJ26587.1 - 4.2e-16 58.4 0.0 1e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 OAJ26587.1 - 1.6e-12 47.2 0.1 6.4e-12 45.3 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 OAJ26587.1 - 8.2e-12 44.8 0.2 5.6e-11 42.1 0.0 2.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_C97 PF05903.9 OAJ26588.1 - 1.7e-38 131.7 0.0 4e-38 130.5 0.0 1.6 2 0 0 2 2 2 1 PPPDE putative peptidase domain SRR1 PF07985.7 OAJ26588.1 - 1.1e-15 57.2 0.3 5e-15 55.1 0.1 2.2 2 0 0 2 2 2 1 SRR1 PIF1 PF05970.9 OAJ26627.1 - 5.1e-20 71.7 0.0 7.4e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ26627.1 - 3.6e-10 39.7 0.0 1.1e-09 38.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ26627.1 - 1.2e-07 31.3 0.1 4.8e-07 29.4 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 OAJ26627.1 - 0.00045 20.2 0.4 0.0017 18.3 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 OAJ26627.1 - 0.0038 16.8 1.0 1.8 8.0 0.1 2.7 2 1 1 3 3 3 2 AAA domain Torsin PF06309.6 OAJ26627.1 - 0.0059 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Torsin AAA_22 PF13401.1 OAJ26627.1 - 0.013 15.6 0.0 0.035 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 OAJ26627.1 - 0.014 14.8 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 OAJ26627.1 - 0.046 13.3 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 OAJ26627.1 - 0.047 13.7 0.0 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ26627.1 - 0.053 13.2 0.1 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 OAJ26627.1 - 0.062 13.4 0.0 0.18 12.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 OAJ26627.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) GST_C_4 PF14834.1 OAJ26628.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribosom_S12_S23 PF00164.20 OAJ26669.1 - 3.2e-45 152.4 0.1 4.2e-45 152.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S17e PF00833.13 OAJ26672.1 - 8.4e-58 193.4 0.0 1e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S8 PF00410.14 OAJ26673.1 - 1.9e-23 82.6 0.0 2.6e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 FAD_binding_7 PF03441.9 OAJ26710.1 - 3.6e-60 203.5 0.9 5.7e-60 202.8 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 OAJ26710.1 - 3.7e-20 72.3 0.0 7.6e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase 7TMR-DISMED2 PF07696.6 OAJ26710.1 - 0.064 12.6 0.3 0.27 10.6 0.1 2.1 2 0 0 2 2 2 0 7TMR-DISM extracellular 2 CRAL_TRIO_2 PF13716.1 OAJ26711.1 - 5.5e-31 107.4 0.0 1e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 OAJ26711.1 - 2e-23 82.6 0.0 3.5e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Nucleoplasmin PF03066.10 OAJ26711.1 - 0.0038 16.7 1.1 0.01 15.3 0.7 1.7 1 0 0 1 1 1 1 Nucleoplasmin SelP_N PF04592.9 OAJ26712.1 - 8.4 5.6 13.4 11 5.2 0.4 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region GFO_IDH_MocA PF01408.17 OAJ26713.1 - 6.2e-17 62.2 0.0 1.2e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 OAJ26713.1 - 2.6e-11 43.2 0.0 6.1e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 OAJ26713.1 - 0.058 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Senescence_reg PF04520.8 OAJ26764.1 - 0.38 11.2 2.2 1.1 9.8 1.5 1.9 1 1 0 1 1 1 0 Senescence regulator Nuc-transf PF10127.4 OAJ26765.1 - 0.072 12.4 0.1 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Predicted nucleotidyltransferase DUF605 PF04652.11 OAJ26767.1 - 0.0072 15.7 21.6 0.0079 15.6 15.0 1.1 1 0 0 1 1 1 1 Vta1 like DUF2036 PF09724.4 OAJ26808.1 - 5.2e-50 170.4 0.0 7.7e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Peptidase_S8 PF00082.17 OAJ26810.1 - 1.5e-41 142.4 0.0 2.8e-41 141.5 0.0 1.4 1 1 0 1 1 1 1 Subtilase family PA PF02225.17 OAJ26810.1 - 4.5e-08 32.7 1.0 1e-07 31.5 0.1 2.0 2 0 0 2 2 2 1 PA domain DUF1034 PF06280.7 OAJ26810.1 - 4.2e-07 30.3 0.1 1.1e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Lipase_3 PF01764.20 OAJ26812.1 - 4.2e-23 81.5 0.0 5.6e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 OAJ26812.1 - 0.01 15.6 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAJ26812.1 - 0.02 14.4 0.1 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_9 PF10081.4 OAJ26812.1 - 0.032 12.9 0.1 5.6 5.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta-hydrolase family HMG_box PF00505.14 OAJ26813.1 - 0.044 14.0 6.2 0.082 13.1 4.3 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box HMG_box PF00505.14 OAJ26814.1 - 4.3e-09 36.5 3.6 4.6e-05 23.6 1.2 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ26814.1 - 0.0031 17.8 0.7 0.0077 16.5 0.5 1.6 1 0 0 1 1 1 1 HMG-box domain Fimbrial_K88 PF02432.10 OAJ26814.1 - 0.06 12.7 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Fimbrial, major and minor subunit Drf_GBD PF06371.8 OAJ26860.1 - 1.6e-13 50.4 0.0 2.7e-12 46.4 0.0 2.4 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain 2OG-FeII_Oxy_2 PF13532.1 OAJ26862.1 - 3.2e-15 56.4 0.0 9e-15 55.0 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ26862.1 - 0.0041 17.3 0.0 0.019 15.2 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Serglycin PF04360.7 OAJ26862.1 - 0.68 9.6 4.1 2 8.1 2.6 1.9 2 0 0 2 2 2 0 Serglycin ATP-synt_DE_N PF02823.11 OAJ26864.1 - 3.8e-19 68.2 0.0 5.3e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Cas_Csa5 PF09702.5 OAJ26864.1 - 0.12 12.4 0.6 0.65 10.1 0.1 2.2 2 1 1 3 3 3 0 CRISPR-associated protein (Cas_Csa5) DBR1 PF05011.8 OAJ26865.1 - 3.8e-12 46.3 0.0 4.4e-11 42.8 0.0 2.4 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 OAJ26865.1 - 4.9e-05 22.8 1.2 9.4e-05 21.8 0.8 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PQ-loop PF04193.9 OAJ26903.1 - 4.7e-10 38.8 0.4 4.7e-10 38.8 0.3 1.6 2 0 0 2 2 2 1 PQ loop repeat Form-deh_trans PF09163.6 OAJ26903.1 - 0.002 17.5 0.1 0.0038 16.6 0.1 1.4 1 0 0 1 1 1 1 Formate dehydrogenase N, transmembrane Na_H_Exchanger PF00999.16 OAJ26904.1 - 0.0018 16.9 0.3 0.0024 16.4 0.2 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ded_cyto PF06920.8 OAJ26943.1 - 1.4e-36 125.4 0.2 1.4e-35 122.1 0.0 2.4 2 0 0 2 2 2 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 OAJ26943.1 - 1.1e-31 109.8 0.0 3e-21 75.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins CK_II_beta PF01214.13 OAJ26945.1 - 1.2e-72 243.2 0.0 1.5e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit FAD_binding_8 PF08022.7 OAJ26946.1 - 4.1e-19 68.4 0.0 8.7e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 OAJ26946.1 - 6.2e-14 52.1 0.1 3.5e-12 46.4 0.0 3.2 2 2 1 3 3 3 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 OAJ26946.1 - 4.9e-09 36.3 9.6 5.9e-09 36.0 5.6 1.9 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 OAJ26946.1 - 0.0022 18.0 0.0 0.0061 16.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain PAT1 PF09770.4 OAJ26947.1 - 8.3e-158 527.0 20.6 1.5e-156 522.9 14.3 2.5 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 GIDA_assoc_3 PF13932.1 OAJ26947.1 - 1.4 9.0 4.4 7.4 6.7 0.3 2.9 3 0 0 3 3 3 0 GidA associated domain 3 ELYS PF13934.1 OAJ26948.1 - 1.3e-07 31.5 1.5 5.1e-07 29.6 1.0 1.8 1 1 0 1 1 1 1 Nuclear pore complex assembly Serglycin PF04360.7 OAJ26948.1 - 2.3 7.9 8.2 72 3.0 4.1 3.7 4 0 0 4 4 4 0 Serglycin Epimerase PF01370.16 OAJ26993.1 - 1.1e-07 31.5 0.0 1.5e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 OAJ26993.1 - 1.8e-06 27.9 0.1 3.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 OAJ26993.1 - 0.0002 21.4 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 OAJ26993.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NIR_SIR PF01077.17 OAJ26994.1 - 7.4e-44 148.8 0.0 8.6e-38 129.1 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 OAJ26994.1 - 1.9e-28 97.8 0.0 3.6e-14 52.1 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 OAJ26994.1 - 6.3e-27 94.3 0.0 1.3e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 OAJ26994.1 - 3.5e-09 36.5 0.0 3.5e-09 36.5 0.0 2.6 3 0 0 3 3 3 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg HtaA PF04213.8 OAJ26994.1 - 0.032 14.4 0.1 0.066 13.4 0.1 1.4 1 0 0 1 1 1 0 Htaa Toprim_N PF08275.6 OAJ26995.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA primase catalytic core, N-terminal domain HsbA PF12296.3 OAJ26996.1 - 1.6e-05 24.7 7.9 0.017 14.9 1.1 2.5 2 1 1 3 3 3 2 Hydrophobic surface binding protein A GST_N_3 PF13417.1 OAJ26997.1 - 1.6e-15 57.0 0.0 4.3e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAJ26997.1 - 1.3e-12 47.6 0.0 2.2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ26997.1 - 6.2e-11 42.1 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Aldo_ket_red PF00248.16 OAJ27054.1 - 2.9e-15 55.8 0.0 2.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family zf-UBR PF02207.15 OAJ27055.1 - 0.098 12.3 7.9 0.19 11.4 5.3 1.6 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Stress-antifung PF01657.12 OAJ27055.1 - 0.17 12.1 5.7 0.22 11.8 4.0 1.2 1 0 0 1 1 1 0 Salt stress response/antifungal Dickkopf_N PF04706.7 OAJ27055.1 - 0.45 10.7 5.9 0.67 10.1 4.1 1.3 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Gpi1 PF05024.10 OAJ27058.1 - 3.7e-41 140.8 0.5 5.9e-41 140.2 0.3 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DUF443 PF04276.7 OAJ27059.1 - 0.19 11.1 8.2 0.54 9.6 1.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF443) Chromate_transp PF02417.10 OAJ27059.1 - 0.86 9.1 19.5 0.027 14.0 3.8 2.7 2 1 0 2 2 2 0 Chromate transporter Rop PF01815.11 OAJ27060.1 - 0.12 11.7 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Rop protein MelC1 PF06236.6 OAJ27063.1 - 0.039 13.9 2.4 0.12 12.3 0.8 2.1 1 1 1 2 2 2 0 Tyrosinase co-factor MelC1 DUF1155 PF06633.6 OAJ27063.1 - 0.14 11.4 0.1 0.52 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1155) TMEM171 PF15471.1 OAJ27064.1 - 0.013 14.3 0.9 0.021 13.6 0.6 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Cutinase PF01083.17 OAJ27065.1 - 2.3e-25 89.3 0.0 2.8e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ27065.1 - 0.0011 18.5 0.1 0.0013 18.3 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ27065.1 - 0.0014 18.5 0.1 0.0016 18.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ27065.1 - 0.01 15.5 0.2 0.014 15.1 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Nsp3_PL2pro PF12124.3 OAJ27065.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain Fib_alpha PF08702.5 OAJ27066.1 - 0.1 12.7 0.3 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family YgaB PF14182.1 OAJ27066.1 - 0.14 12.3 1.5 0.24 11.6 0.7 1.6 1 1 0 1 1 1 0 YgaB-like protein DDE_Tnp_4 PF13359.1 OAJ27116.1 - 2.9e-30 104.9 0.0 3.9e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ27116.1 - 1.4e-07 31.1 0.0 3.9e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 OAJ27116.1 - 0.00053 20.1 1.1 0.001 19.2 0.1 1.9 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.16 OAJ27116.1 - 0.002 17.6 0.0 0.0051 16.3 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain Fer4 PF00037.22 OAJ27117.1 - 5.2e-15 54.3 16.3 7.9e-09 34.7 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 OAJ27117.1 - 7.1e-13 48.7 10.8 1.1e-12 48.1 7.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 OAJ27117.1 - 1.1e-10 41.0 23.2 2.4e-08 33.6 9.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 OAJ27117.1 - 1.2e-10 41.9 7.7 2.7e-05 24.8 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 OAJ27117.1 - 1.3e-10 40.9 5.1 2.9e-05 23.8 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 OAJ27117.1 - 4.4e-10 39.4 29.7 6e-06 26.1 8.2 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.1 OAJ27117.1 - 9.1e-10 38.6 11.2 1.9e-09 37.6 7.8 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 OAJ27117.1 - 5.4e-09 35.4 14.6 4.4e-05 23.1 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 OAJ27117.1 - 2e-08 33.7 18.0 0.00035 20.3 3.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 OAJ27117.1 - 2.5e-07 30.9 28.5 0.00036 20.8 7.5 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 OAJ27117.1 - 6.4e-07 29.2 12.1 0.00031 20.8 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 OAJ27117.1 - 8.2e-06 26.1 10.6 0.0067 16.8 0.6 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 OAJ27117.1 - 5.8e-05 23.3 12.0 0.02 15.2 0.5 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 OAJ27117.1 - 0.0012 19.3 12.7 0.14 12.7 1.1 2.7 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 OAJ27117.1 - 0.011 16.2 18.1 0.039 14.5 3.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 OAJ27117.1 - 0.024 14.7 4.5 0.24 11.5 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_11 PF13247.1 OAJ27117.1 - 0.027 14.3 3.7 0.04 13.7 2.6 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain ACOX PF01756.14 OAJ27120.1 - 1.5e-39 135.3 0.4 3.2e-39 134.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 OAJ27120.1 - 2.2e-22 79.6 0.1 4.6e-22 78.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 OAJ27120.1 - 8.6e-11 41.1 0.4 2.2e-10 39.8 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 OAJ27120.1 - 1.3e-05 25.3 0.5 0.00055 20.0 0.4 2.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAJ27120.1 - 0.11 13.1 0.0 0.45 11.1 0.0 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Myb_DNA-bind_3 PF12776.2 OAJ27121.1 - 7.4e-16 58.5 0.0 1.2e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ27121.1 - 3.5e-06 27.0 0.5 0.00012 22.1 0.0 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain CAF-1_p150 PF11600.3 OAJ27121.1 - 0.88 8.8 8.1 0.078 12.3 0.6 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal STT3 PF02516.9 OAJ27166.1 - 9.4e-135 450.2 34.2 8.6e-133 443.8 23.7 2.1 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit DUF1978 PF09321.5 OAJ27166.1 - 0.18 11.2 0.1 0.27 10.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) RhoGAP PF00620.22 OAJ27167.1 - 8.8e-37 126.0 0.0 1.9e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain tRNA-synt_1g PF09334.6 OAJ27168.1 - 3.6e-144 480.2 0.0 4.5e-144 479.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 OAJ27168.1 - 1.1e-08 33.5 0.5 5.2e-05 21.4 0.0 3.3 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) WHEP-TRS PF00458.15 OAJ27168.1 - 7.6e-06 25.4 3.5 7.6e-06 25.4 2.5 2.0 2 0 0 2 2 2 1 WHEP-TRS domain DZR PF12773.2 OAJ27168.1 - 0.067 13.0 4.0 0.15 11.9 2.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon DUF2201_N PF13203.1 OAJ27168.1 - 0.16 11.1 4.8 0.27 10.3 3.3 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain PepSY_2 PF13670.1 OAJ27168.1 - 7.5 6.5 10.6 1.3 8.9 4.2 1.9 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain Brix PF04427.13 OAJ27169.1 - 2.6e-38 131.6 0.0 3.8e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain Trypan_PARP PF05887.6 OAJ27169.1 - 1.3 8.8 22.2 2.9 7.7 1.9 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Daxx PF03344.10 OAJ27169.1 - 6.3 5.1 27.4 0.054 11.9 12.2 1.9 2 0 0 2 2 2 0 Daxx Family DUF2910 PF11139.3 OAJ27170.1 - 0.87 8.6 0.0 0.87 8.6 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2910) zf-CCHC_4 PF14392.1 OAJ27172.1 - 0.21 11.2 1.9 0.87 9.3 0.9 2.2 2 0 0 2 2 2 0 Zinc knuckle CRAL_TRIO PF00650.15 OAJ27243.1 - 0.12 11.9 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 CRAL/TRIO domain TPK_catalytic PF04263.11 OAJ27244.1 - 5.1e-17 61.5 0.0 8.6e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 OAJ27244.1 - 2.1e-09 36.9 0.0 3.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Ferric_reduct PF01794.14 OAJ27245.1 - 4e-21 75.3 10.8 4e-21 75.3 7.5 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 OAJ27245.1 - 1.8e-17 63.6 0.0 2.6e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 OAJ27245.1 - 1.7e-09 37.4 0.0 5e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 OAJ27245.1 - 0.037 14.6 0.0 0.78 10.3 0.0 2.3 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain TniQ PF06527.6 OAJ27247.1 - 0.32 11.1 2.4 0.73 10.0 1.6 1.5 1 0 0 1 1 1 0 TniQ MitoNEET_N PF10660.4 OAJ27249.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Apolipoprotein PF01442.13 OAJ27250.1 - 0.0007 19.1 10.9 0.002 17.6 7.6 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain HAUS-augmin3 PF14932.1 OAJ27250.1 - 0.0014 17.8 5.9 0.0014 17.8 4.1 1.3 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 3 Baculo_PEP_C PF04513.7 OAJ27250.1 - 0.016 15.0 6.9 0.11 12.3 1.7 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hemerythrin PF01814.18 OAJ27250.1 - 0.088 12.9 3.8 0.67 10.1 0.1 2.1 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain SF-assemblin PF06705.6 OAJ27250.1 - 0.093 11.8 2.0 0.14 11.2 1.4 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin Exonuc_VII_L PF02601.10 OAJ27250.1 - 0.12 11.5 2.9 0.15 11.2 2.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1640 PF07798.6 OAJ27250.1 - 0.17 11.9 5.3 1.2 9.1 3.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Bacillus_HBL PF05791.6 OAJ27250.1 - 0.2 11.0 4.2 0.16 11.3 1.4 1.8 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Snapin_Pallidin PF14712.1 OAJ27250.1 - 0.2 11.9 4.6 0.28 11.5 2.4 1.9 1 1 0 1 1 1 0 Snapin/Pallidin DUF4164 PF13747.1 OAJ27250.1 - 0.53 10.4 3.5 0.95 9.6 2.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Fzo_mitofusin PF04799.8 OAJ27250.1 - 2.9 7.2 7.8 1.4 8.3 2.1 2.4 1 1 2 3 3 3 0 fzo-like conserved region FlxA PF14282.1 OAJ27250.1 - 3.2 7.7 9.4 4.3 7.3 6.2 1.5 1 1 0 1 1 1 0 FlxA-like protein OmpH PF03938.9 OAJ27250.1 - 6.3 6.7 9.5 14 5.5 6.6 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) PIF1 PF05970.9 OAJ27251.1 - 1.7e-22 79.8 0.0 2.1e-21 76.2 0.0 2.1 2 0 0 2 2 2 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ27251.1 - 1.6e-11 44.3 0.1 3.9e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 OAJ27251.1 - 8e-10 38.6 0.0 3.3e-09 36.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ27251.1 - 1.5e-07 31.0 1.7 2.6e-06 27.0 0.1 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 OAJ27251.1 - 0.0062 16.5 1.7 0.014 15.3 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 OAJ27251.1 - 0.047 13.4 0.1 0.18 11.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Torsin PF06309.6 OAJ27251.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.21 OAJ27251.1 - 0.064 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Peptidase_M48 PF01435.13 OAJ27319.1 - 1.3e-37 129.6 0.0 3.5e-36 124.8 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 OAJ27319.1 - 0.0079 15.1 0.1 0.0079 15.1 0.0 2.0 2 0 0 2 2 2 1 BlaR1 peptidase M56 Abhydrolase_6 PF12697.2 OAJ27320.1 - 5.7e-27 95.0 0.0 7.2e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ27320.1 - 2.7e-13 49.8 0.0 3.9e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ27320.1 - 2.7e-10 40.1 0.0 8e-10 38.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAJ27320.1 - 0.052 13.4 0.0 0.26 11.1 0.0 2.2 2 1 0 2 2 2 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 OAJ27320.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 OAJ27320.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_4 PF08386.5 OAJ27320.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Acyl-CoA_dh_1 PF00441.19 OAJ27321.1 - 8.5e-37 126.5 0.1 1.2e-36 126.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ27321.1 - 1.1e-16 60.0 0.1 2e-16 59.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 OAJ27321.1 - 1e-14 55.0 0.2 2.7e-14 53.7 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAJ27321.1 - 3.3e-10 40.3 0.1 5.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HD PF01966.17 OAJ27322.1 - 0.055 13.4 0.8 0.25 11.3 0.5 2.1 1 1 0 1 1 1 0 HD domain Orn_Arg_deC_N PF02784.11 OAJ27323.1 - 1.6e-35 122.4 0.0 2.3e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 OAJ27323.1 - 5e-17 61.6 0.0 8.4e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain eIF-3c_N PF05470.7 OAJ27324.1 - 1.1e-182 608.3 4.1 1.1e-182 608.3 2.8 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 OAJ27324.1 - 5.2e-08 33.1 0.0 1.8e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 PCI domain DUF3818 PF12825.2 OAJ27324.1 - 0.11 11.1 0.5 0.26 9.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) DUF3439 PF11921.3 OAJ27324.1 - 1.7 8.3 6.5 0.11 12.2 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Aconitase_2_N PF06434.8 OAJ27326.1 - 0.054 12.8 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus APH PF01636.18 OAJ27328.1 - 9.3e-20 71.3 0.4 9.3e-20 71.3 0.3 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 OAJ27328.1 - 0.043 13.1 0.0 0.84 8.9 0.0 2.1 2 0 0 2 2 2 0 RIO1 family TIM21 PF08294.6 OAJ27329.1 - 1.1e-12 47.8 0.1 1.8e-11 43.8 0.0 2.6 2 1 0 2 2 2 1 TIM21 DUF1744 PF08490.7 OAJ27331.1 - 9.6e-119 396.4 0.0 1.5e-118 395.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 OAJ27331.1 - 8.3e-63 212.2 0.0 1.7e-62 211.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 OAJ27331.1 - 4.4e-19 68.5 0.0 1.3e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 OAJ27331.1 - 2.5e-09 36.9 0.1 8.4e-09 35.2 0.0 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 OAJ27331.1 - 9.6e-06 25.4 0.0 4.8e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 RNase_H superfamily IDO PF01231.13 OAJ27332.1 - 2.3e-46 158.0 0.0 3.4e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase HSP9_HSP12 PF04119.7 OAJ27333.1 - 4.3e-18 65.1 6.1 4.3e-18 65.1 4.3 1.7 2 0 0 2 2 2 1 Heat shock protein 9/12 Pol_alpha_B_N PF08418.5 OAJ27333.1 - 0.23 10.9 3.6 0.24 10.8 2.5 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Endosulfine PF04667.12 OAJ27334.1 - 1.7e-17 63.1 0.0 3.8e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DDE_3 PF13358.1 OAJ27335.1 - 1.3e-29 102.7 0.0 3.9e-29 101.2 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAJ27335.1 - 1.6e-08 35.2 4.7 1.7e-08 35.0 0.3 2.8 2 1 1 3 3 3 1 Homeodomain-like domain rve PF00665.21 OAJ27335.1 - 2e-06 27.8 0.0 4.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_29 PF13551.1 OAJ27335.1 - 0.00029 20.9 0.2 0.0016 18.5 0.1 2.3 1 1 1 2 2 2 1 Winged helix-turn helix HTH_33 PF13592.1 OAJ27335.1 - 0.00032 20.1 0.1 0.00096 18.6 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_IS630 PF01710.11 OAJ27335.1 - 0.00065 19.3 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Transposase HTH_7 PF02796.10 OAJ27335.1 - 0.061 13.1 0.3 1.7 8.5 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DDE_Tnp_ISAZ013 PF07592.6 OAJ27335.1 - 0.15 10.7 0.1 3.4 6.3 0.0 2.1 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain ERG4_ERG24 PF01222.12 OAJ27336.1 - 1.4e-139 465.3 4.1 1.6e-139 465.1 2.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 OAJ27336.1 - 3.1e-05 23.3 0.1 6.4e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 OAJ27336.1 - 0.00016 21.7 2.0 0.00034 20.6 0.0 2.7 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.9 OAJ27336.1 - 0.0054 16.9 0.0 0.018 15.2 0.0 1.9 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF4448 PF14610.1 OAJ27337.1 - 0.015 14.8 0.2 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) SAPS PF04499.10 OAJ27338.1 - 0.031 12.9 3.4 0.048 12.3 2.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Band_7 PF01145.20 OAJ27339.1 - 0.1 12.5 22.1 21 4.9 0.0 4.0 2 1 0 2 2 2 0 SPFH domain / Band 7 family DUF4230 PF14014.1 OAJ27339.1 - 3.3 7.5 8.2 7.1 6.4 5.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4230) CAF-1_p150 PF11600.3 OAJ27339.1 - 7.3 5.8 7.3 13 5.0 5.1 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FA_hydroxylase PF04116.8 OAJ27340.1 - 6e-13 49.1 6.6 6.2e-13 49.1 2.8 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RVT_2 PF07727.9 OAJ27341.1 - 2.4e-22 79.1 0.0 3.5e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ27341.1 - 7.8e-21 74.4 0.0 1.6e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ27341.1 - 2.7e-08 33.3 0.0 6.4e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_2 PF14227.1 OAJ27341.1 - 1.1e-06 28.1 0.0 2.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ27341.1 - 5.1e-05 23.0 0.0 9.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ27341.1 - 0.00012 21.7 9.0 0.00075 19.3 1.9 2.5 2 0 0 2 2 2 2 Zinc knuckle rve_3 PF13683.1 OAJ27341.1 - 0.0036 16.7 0.0 0.0099 15.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_4 PF14392.1 OAJ27341.1 - 0.52 10.0 5.9 5.2 6.8 0.6 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ27341.1 - 2.3 7.7 5.5 1.5 8.4 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle Macoilin PF09726.4 OAJ27341.1 - 3.7 5.7 7.1 5.4 5.1 4.9 1.1 1 0 0 1 1 1 0 Transmembrane protein WD40 PF00400.27 OAJ27342.1 - 1.4e-25 88.1 1.2 5.3e-07 29.2 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat PD40 PF07676.7 OAJ27342.1 - 0.063 12.9 0.7 0.17 11.5 0.1 2.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Cpn60_TCP1 PF00118.19 OAJ27343.1 - 1.9e-143 478.5 0.2 2.2e-143 478.4 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TFIIB PF00382.14 OAJ27344.1 - 2.5e-26 91.2 0.0 1.1e-17 63.5 0.0 2.8 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 OAJ27344.1 - 1.7e-22 79.4 4.6 1.7e-22 79.4 3.2 4.6 3 1 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 OAJ27344.1 - 5.4e-07 28.8 1.1 1.1e-06 27.8 0.8 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 OAJ27344.1 - 3.4e-06 26.6 0.0 0.11 12.0 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Ribosomal_S27e PF01667.12 OAJ27344.1 - 0.091 12.3 1.2 0.17 11.4 0.8 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 DNA_RNApol_7kD PF03604.8 OAJ27344.1 - 0.24 10.8 4.2 0.49 9.9 2.9 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Las1 PF04031.8 OAJ27345.1 - 5.5e-44 149.5 0.0 7.4e-44 149.1 0.0 1.1 1 0 0 1 1 1 1 Las1-like Methyltransf_31 PF13847.1 OAJ27346.1 - 1.2e-12 47.7 0.0 1.7e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ27346.1 - 1.2e-12 48.4 0.0 1.9e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ27346.1 - 4.7e-06 27.0 0.0 8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ27346.1 - 8.2e-06 25.8 0.0 1.9e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 OAJ27346.1 - 4.9e-05 23.0 0.0 6.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ27346.1 - 8.8e-05 22.8 0.0 0.00017 21.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ27346.1 - 0.00025 21.4 0.0 0.004 17.6 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ27346.1 - 0.00053 19.7 0.0 0.00098 18.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 OAJ27346.1 - 0.12 11.6 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Spo12 PF05032.7 OAJ27347.1 - 2.2e-09 36.7 4.6 4.2e-09 35.8 3.2 1.5 1 0 0 1 1 1 1 Spo12 family SnoaL_2 PF12680.2 OAJ27347.1 - 0.001 19.4 0.0 0.0017 18.7 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain ubiquitin PF00240.18 OAJ27348.1 - 2e-24 84.7 0.1 2.2e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 OAJ27348.1 - 1.6e-15 56.4 0.0 1.8e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAJ27348.1 - 0.0003 20.9 0.0 0.00038 20.6 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-like domain Smg4_UPF3 PF03467.10 OAJ27349.1 - 2e-32 112.5 0.0 2e-32 112.5 0.0 2.5 2 1 0 2 2 2 1 Smg-4/UPF3 family 2-Hacid_dh_C PF02826.14 OAJ27350.1 - 2.3e-40 137.6 0.0 2.8e-37 127.5 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAJ27350.1 - 2.7e-24 85.1 0.0 3.6e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Mito_carr PF00153.22 OAJ27351.1 - 3.8e-50 167.5 5.3 1.2e-16 60.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SRP1_TIP1 PF00660.12 OAJ27351.1 - 0.094 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Seripauperin and TIP1 family zf-CCHC PF00098.18 OAJ27353.1 - 7.9e-10 38.1 37.9 5.6e-07 29.1 1.1 5.7 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ27353.1 - 0.056 12.9 15.4 2.5 7.6 0.2 3.4 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ27353.1 - 7.8 6.2 29.0 0.75 9.5 0.6 4.7 5 0 0 5 5 5 0 Zinc knuckle PH PF00169.24 OAJ27355.1 - 1.2e-08 35.1 0.0 8.8e-08 32.2 0.0 2.2 1 1 0 1 1 1 1 PH domain PH_9 PF15410.1 OAJ27355.1 - 3.1e-08 33.8 0.6 0.0012 18.9 0.1 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 OAJ27355.1 - 0.00019 21.6 0.1 0.09 13.0 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain Nop14 PF04147.7 OAJ27355.1 - 0.92 7.3 6.0 1.3 6.7 4.2 1.1 1 0 0 1 1 1 0 Nop14-like family Glyco_transf_54 PF04666.8 OAJ27357.1 - 9.8e-08 31.0 0.0 0.029 13.1 0.0 3.1 3 0 0 3 3 3 3 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region GCR1_C PF12550.3 OAJ27358.1 - 6.9e-06 25.8 0.1 1.5e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_23 PF13384.1 OAJ27358.1 - 0.00068 19.1 1.3 0.075 12.7 0.0 3.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 OAJ27358.1 - 0.014 15.3 0.7 0.98 9.4 0.0 3.4 3 0 0 3 3 3 0 Transposase HTH_28 PF13518.1 OAJ27358.1 - 0.036 14.0 0.2 0.85 9.6 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain Sulfate_tra_GLY PF13792.1 OAJ27359.1 - 5.6e-09 35.5 0.1 1.1e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif Zn_clus PF00172.13 OAJ27360.1 - 1.6e-06 27.8 4.8 1e-05 25.3 3.4 2.0 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myosin_tail_1 PF01576.14 OAJ27360.1 - 0.075 10.7 0.3 0.11 10.2 0.2 1.1 1 0 0 1 1 1 0 Myosin tail Fungal_trans PF04082.13 OAJ27362.1 - 1.7e-05 23.8 0.0 4.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ27362.1 - 0.0022 17.8 5.9 0.22 11.4 0.5 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DSPc PF00782.15 OAJ27363.1 - 5.7e-06 25.9 0.0 1.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAJ27363.1 - 2.2e-05 23.8 0.0 0.0069 15.7 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase CDKN3 PF05706.7 OAJ27363.1 - 0.039 13.3 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PPR_2 PF13041.1 OAJ27364.1 - 1.3e-35 121.1 0.0 1.3e-11 44.2 0.0 9.3 8 2 3 11 11 11 6 PPR repeat family PPR_3 PF13812.1 OAJ27364.1 - 3.5e-32 107.9 2.0 1.6e-05 24.7 0.0 10.8 11 0 0 11 11 11 5 Pentatricopeptide repeat domain PPR PF01535.15 OAJ27364.1 - 3.1e-27 92.6 5.2 9.9e-05 22.0 0.0 11.2 11 2 0 11 11 11 5 PPR repeat PPR_1 PF12854.2 OAJ27364.1 - 3.2e-19 68.1 3.7 5.6e-07 28.9 0.0 7.0 9 1 0 9 9 9 3 PPR repeat TPR_7 PF13176.1 OAJ27364.1 - 0.0027 17.3 0.0 8.2 6.4 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ27364.1 - 0.11 12.2 0.0 28 4.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Cyclin_N PF00134.18 OAJ27365.1 - 2.2e-39 133.9 0.7 7.8e-38 128.9 0.3 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ27365.1 - 1e-25 89.9 0.0 2e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain CBF PF03914.12 OAJ27366.1 - 5.8e-34 116.9 0.0 4.4e-33 114.0 0.0 2.5 1 1 0 1 1 1 1 CBF/Mak21 family Adaptin_N PF01602.15 OAJ27366.1 - 0.083 11.1 0.0 0.79 7.9 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region zf-C2H2_4 PF13894.1 OAJ27367.1 - 0.021 15.1 11.5 0.16 12.4 0.3 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ27367.1 - 0.26 11.6 6.4 4.2 7.8 1.0 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ27367.1 - 0.93 9.9 14.7 0.71 10.3 0.5 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type 4HBT_3 PF13622.1 OAJ27368.1 - 4.5e-32 111.8 1.0 6.1e-32 111.3 0.7 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 OAJ27368.1 - 0.00023 20.8 0.0 0.00048 19.7 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA thioesterase DPBB_1 PF03330.13 OAJ27369.1 - 7.6e-07 29.0 0.0 7.6e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ27369.1 - 0.0046 16.6 0.9 0.01 15.5 0.6 1.6 1 0 0 1 1 1 1 Barwin family DUF1180 PF06679.7 OAJ27369.1 - 0.14 12.0 8.6 0.083 12.7 4.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF737 PF05300.6 OAJ27369.1 - 0.68 9.8 7.6 1.1 9.2 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) FNIP_N PF14636.1 OAJ27369.1 - 1 9.8 7.9 2.1 8.8 5.5 1.5 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Neisseria_TspB PF05616.8 OAJ27369.1 - 2.2 6.5 8.9 3 6.1 6.2 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Mito_fiss_reg PF05308.6 OAJ27369.1 - 5.4 6.3 13.4 8.7 5.6 9.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4551 PF15087.1 OAJ27369.1 - 7.9 4.7 10.2 10 4.3 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MCPVI PF02993.9 OAJ27369.1 - 8.3 6.4 11.0 14 5.7 7.6 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Ribosomal_L14 PF00238.14 OAJ27370.1 - 1.1e-32 112.3 0.0 2.2e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Kri1_C PF12936.2 OAJ27370.1 - 3.8e-23 81.2 0.1 3.8e-23 81.2 0.0 4.1 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 OAJ27370.1 - 5.2e-20 71.6 15.8 5.2e-20 71.6 10.9 5.2 4 1 1 5 5 5 1 KRI1-like family Toxin_29 PF08116.6 OAJ27371.1 - 0.26 11.1 0.0 0.26 11.1 0.0 5.5 5 1 1 6 6 6 0 PhTx neurotoxin family Colipase-like PF15083.1 OAJ27371.1 - 1.4 8.9 26.0 2.8 7.9 0.0 4.1 2 1 3 5 5 5 0 Colipase-like zf-Sec23_Sec24 PF04810.10 OAJ27372.1 - 0.11 12.1 0.2 0.23 11.0 0.2 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Tubulin_3 PF14881.1 OAJ27374.1 - 2.4e-28 98.8 13.5 4.3e-19 68.6 1.2 4.3 2 1 1 3 3 3 3 Tubulin domain Misat_Tub_SegII PF10644.4 OAJ27374.1 - 7.5e-26 90.4 0.0 3.1e-25 88.4 0.0 2.1 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain MT-A70 PF05063.9 OAJ27375.1 - 9.5e-49 165.3 0.0 7.7e-33 113.5 0.0 2.2 2 0 0 2 2 2 2 MT-A70 Methyltransf_26 PF13659.1 OAJ27375.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Retrotrans_gag PF03732.12 OAJ27376.1 - 0.069 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein DUF2205 PF10224.4 OAJ27376.1 - 0.11 12.1 0.2 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) RVT_1 PF00078.22 OAJ27377.1 - 5.3e-16 58.6 0.0 1e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ27377.1 - 1.3e-12 47.8 0.0 3.1e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain BUD22 PF09073.5 OAJ27378.1 - 2.1 7.2 4.8 3.4 6.6 3.3 1.2 1 0 0 1 1 1 0 BUD22 MFS_1 PF07690.11 OAJ27381.1 - 1.1e-17 63.8 46.4 1.1e-17 63.8 32.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 OAJ27381.1 - 0.02 14.6 0.3 0.02 14.6 0.2 3.1 3 1 0 3 3 3 0 MFS_1 like family CMAS PF02353.15 OAJ27382.1 - 7.5e-34 117.0 0.4 3.4e-33 114.8 0.3 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 OAJ27382.1 - 2.2e-11 44.0 0.0 4.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ27382.1 - 1.8e-10 40.6 0.0 5.2e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ27382.1 - 2.7e-07 30.4 0.0 6.2e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ27382.1 - 9.5e-07 29.3 0.0 3.7e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ27382.1 - 7.1e-06 26.4 0.0 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ27382.1 - 7.2e-06 25.4 0.0 1.6e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 OAJ27382.1 - 1.5e-05 25.2 0.0 4.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 OAJ27382.1 - 0.0028 16.7 0.0 0.005 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.10 OAJ27382.1 - 0.017 14.2 0.0 0.037 13.1 0.0 1.5 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G TehB PF03848.9 OAJ27382.1 - 0.025 13.7 0.1 0.091 11.9 0.0 1.8 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 OAJ27382.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 OAJ27382.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Chitin_synth_2 PF03142.10 OAJ27383.1 - 3e-281 933.4 0.0 3.6e-281 933.1 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 OAJ27383.1 - 8.6e-17 61.4 0.7 2e-16 60.2 0.5 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ27383.1 - 3.2e-16 59.8 0.0 3.8e-15 56.3 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 OAJ27383.1 - 3.5e-05 23.1 0.1 0.00083 18.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 OAJ27383.1 - 0.0052 16.4 0.0 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Abhydrolase_5 PF12695.2 OAJ27385.1 - 0.0021 17.8 0.1 0.018 14.8 0.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 OAJ27385.1 - 0.089 11.6 0.0 0.21 10.4 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Herpes_gE PF02480.11 OAJ27385.1 - 0.12 10.5 0.0 0.22 9.7 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2919 PF11143.3 OAJ27385.1 - 0.24 11.2 0.3 0.48 10.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) Pkinase PF00069.20 OAJ27387.1 - 7.6e-63 212.0 0.0 1.1e-62 211.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ27387.1 - 2.3e-28 98.9 0.0 4e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 OAJ27387.1 - 1e-07 32.3 0.1 1e-07 32.3 0.0 2.8 2 2 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.9 OAJ27387.1 - 0.003 16.6 0.0 0.0058 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ27387.1 - 0.15 10.9 0.1 0.88 8.4 0.0 2.2 2 1 0 2 2 2 0 Kinase-like PAS_9 PF13426.1 OAJ27388.1 - 3.6e-26 91.5 0.0 1.5e-15 57.4 0.0 3.3 3 0 0 3 3 3 2 PAS domain PAS PF00989.19 OAJ27388.1 - 5.4e-16 58.3 0.0 3.3e-09 36.5 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS_3 PF08447.6 OAJ27388.1 - 2e-11 43.8 0.0 5.1e-07 29.6 0.0 3.7 2 1 1 3 3 3 2 PAS fold PAS_4 PF08448.5 OAJ27388.1 - 1.2e-08 34.8 0.0 0.0015 18.5 0.0 4.8 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.1 OAJ27388.1 - 2.1e-05 24.1 0.0 0.0037 17.0 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.1 OAJ27388.1 - 0.0004 20.3 0.0 0.0018 18.2 0.0 2.2 1 1 0 1 1 1 1 PAS domain Kei1 PF08552.6 OAJ27389.1 - 0.071 12.7 4.5 0.1 12.2 3.1 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 PAP1 PF08601.5 OAJ27389.1 - 0.23 11.0 9.5 0.35 10.4 6.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.4 OAJ27389.1 - 1.2 7.3 6.7 1.5 6.9 4.6 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF515 PF04415.7 OAJ27389.1 - 3.3 5.8 15.6 4.8 5.2 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Golgin_A5 PF09787.4 OAJ27389.1 - 7.6 4.9 10.4 11 4.4 7.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF2992 PF11208.3 OAJ27390.1 - 0.077 12.8 0.7 0.15 11.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Phage_int_SAM_1 PF02899.12 OAJ27392.1 - 0.065 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain GCR1_C PF12550.3 OAJ27393.1 - 8.1e-19 67.2 1.3 1.3e-18 66.6 0.9 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes NPV_P10 PF05531.7 OAJ27393.1 - 0.22 11.8 2.1 0.56 10.4 1.4 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein EF-hand_7 PF13499.1 OAJ27394.1 - 0.00035 20.6 0.0 0.00045 20.3 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 OAJ27394.1 - 0.015 14.8 0.1 0.029 13.9 0.0 1.5 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 OAJ27394.1 - 0.025 13.8 0.0 0.051 12.9 0.0 1.5 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 OAJ27394.1 - 0.033 14.0 0.0 0.073 12.9 0.0 1.6 2 0 0 2 2 2 0 EF-hand domain Sugar_tr PF00083.19 OAJ27397.1 - 0.0035 15.9 6.1 0.0046 15.6 4.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter EF_assoc_1 PF08355.7 OAJ27397.1 - 0.058 12.6 1.2 0.13 11.6 0.8 1.5 1 0 0 1 1 1 0 EF hand associated DUF1115 PF06544.7 OAJ27398.1 - 3.5e-06 26.7 0.0 0.00053 19.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1115) NicO PF03824.11 OAJ27399.1 - 6.1e-29 101.2 13.7 3e-12 46.4 0.0 5.0 4 1 1 5 5 5 3 High-affinity nickel-transport protein PDGLE PF13190.1 OAJ27399.1 - 0.03 13.9 3.7 0.045 13.4 0.0 2.9 3 0 0 3 3 3 0 PDGLE domain DUF3818 PF12825.2 OAJ27400.1 - 1e-35 123.0 0.0 1.5e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 OAJ27400.1 - 1.2e-21 76.7 0.0 2.4e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 PX-associated GAS PF13851.1 OAJ27402.1 - 1.9 7.6 16.2 3.9 6.6 11.2 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 OAJ27402.1 - 3.5 7.1 15.9 9.5 5.7 11.0 1.7 1 0 0 1 1 1 0 IncA protein LCD1 PF09798.4 OAJ27402.1 - 4.3 5.2 9.9 4.3 5.2 0.0 2.2 2 0 0 2 2 2 0 DNA damage checkpoint protein DUF1771 PF08590.5 OAJ27406.1 - 5.3e-18 64.7 3.7 7.8e-18 64.2 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 OAJ27406.1 - 2.5e-15 56.4 0.0 4.7e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Smr domain DUF3450 PF11932.3 OAJ27407.1 - 0.0024 17.1 0.1 0.069 12.4 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) NPV_P10 PF05531.7 OAJ27407.1 - 0.0089 16.2 0.2 1.4 9.1 0.0 2.2 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein COMP PF11598.3 OAJ27407.1 - 0.073 13.1 1.0 0.22 11.6 0.1 2.0 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein LEAP-2 PF07359.6 OAJ27407.1 - 0.078 12.6 0.2 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) dsrm PF00035.20 OAJ27408.1 - 0.1 13.2 0.0 0.1 13.2 0.0 2.9 4 1 1 5 5 5 0 Double-stranded RNA binding motif BRF1 PF07741.8 OAJ27408.1 - 5.4 7.3 18.4 0.1 12.8 4.4 2.7 2 1 0 3 3 3 0 Brf1-like TBP-binding domain Ssl1 PF04056.9 OAJ27409.1 - 2.8e-69 232.5 0.0 5.8e-69 231.5 0.0 1.5 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 OAJ27409.1 - 1.5e-14 53.6 7.5 1.5e-14 53.6 5.2 3.2 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 OAJ27409.1 - 1e-11 45.2 0.0 2.5e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Tfb4 PF03850.9 OAJ27409.1 - 0.33 10.1 5.8 3.9 6.6 4.1 2.3 2 1 1 3 3 3 0 Transcription factor Tfb4 DZR PF12773.2 OAJ27409.1 - 1.9 8.4 23.3 0.13 12.0 3.3 3.4 2 1 0 2 2 2 0 Double zinc ribbon DUF1610 PF07754.6 OAJ27409.1 - 4.8 7.3 16.7 0.44 10.7 0.7 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1610) IBR PF01485.16 OAJ27409.1 - 4.8 7.1 16.7 0.13 12.1 4.4 2.7 2 1 0 2 2 2 0 IBR domain Dynein_light PF01221.13 OAJ27410.1 - 2.9e-37 126.5 0.4 3.5e-37 126.2 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Pkinase PF00069.20 OAJ27411.1 - 9.3e-71 238.0 0.0 1.2e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ27411.1 - 2e-45 154.8 0.0 3e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 OAJ27411.1 - 2.9e-21 75.6 0.1 6.4e-21 74.5 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 OAJ27411.1 - 9.6e-05 21.4 0.0 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ27411.1 - 0.018 14.7 0.2 0.65 9.6 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family DSHCT PF08148.7 OAJ27411.1 - 0.021 14.0 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.9 OAJ27411.1 - 0.22 10.5 0.1 1.8 7.5 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family P5CR_dimer PF14748.1 OAJ27412.1 - 8.5e-38 128.6 4.8 1e-37 128.4 2.2 2.0 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 OAJ27412.1 - 1.9e-13 50.6 0.0 4.4e-09 36.6 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent DUF633 PF04816.7 OAJ27412.1 - 0.14 11.5 0.0 2.6 7.3 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF633) PBP1_TM PF14812.1 OAJ27415.1 - 2.3 8.5 5.6 0.69 10.2 0.2 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal rve PF00665.21 OAJ27416.1 - 2.7e-13 50.0 0.0 5.3e-12 45.8 0.0 2.6 2 1 1 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ27416.1 - 2.6e-07 30.1 0.0 2.1e-06 27.2 0.0 2.4 2 1 0 2 2 2 1 GAG-pre-integrase domain UBN2 PF14223.1 OAJ27416.1 - 0.00031 20.5 0.0 0.00062 19.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Transcript_VP30 PF11507.3 OAJ27416.1 - 0.014 15.1 0.4 0.038 13.8 0.0 1.8 2 0 0 2 2 2 0 Ebola virus-specific transcription factor VP30 RVT_2 PF07727.9 OAJ27417.1 - 2.1e-82 275.7 0.0 3e-82 275.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAJ27417.1 - 0.031 13.6 0.0 0.088 12.1 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Tannase PF07519.6 OAJ27418.1 - 1.1e-07 30.9 0.0 1.4e-07 30.6 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Tannase PF07519.6 OAJ27419.1 - 4e-68 230.2 0.2 2.9e-66 224.1 0.1 2.2 1 1 0 1 1 1 1 Tannase and feruloyl esterase Zip PF02535.17 OAJ27419.1 - 0.0083 15.1 3.2 0.012 14.6 2.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter SelP_N PF04592.9 OAJ27419.1 - 3.5 6.9 11.0 7.6 5.8 7.6 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RRM_6 PF14259.1 OAJ27420.1 - 2.4e-34 117.1 0.2 4.4e-08 32.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ27420.1 - 4.5e-27 93.4 0.8 5e-07 29.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ27420.1 - 5.2e-20 71.0 0.2 3.8e-05 23.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ27420.1 - 0.0018 18.1 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif Mob1_phocein PF03637.12 OAJ27421.1 - 8.9e-73 243.6 0.1 1e-72 243.4 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family DUF2380 PF09533.5 OAJ27421.1 - 0.11 11.8 0.0 13 5.1 0.0 2.1 1 1 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) Pyridoxal_deC PF00282.14 OAJ27422.1 - 3.9e-71 239.4 0.0 5.1e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 OAJ27422.1 - 1.7e-05 24.1 0.0 2.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 OAJ27422.1 - 9.1e-05 21.3 0.0 0.00016 20.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 OAJ27422.1 - 0.0064 15.0 0.0 0.0098 14.4 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Rad4 PF03835.10 OAJ27423.1 - 3.2e-27 94.7 0.0 3.2e-27 94.7 0.0 2.4 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 OAJ27423.1 - 1.9e-23 81.9 0.0 3.5e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 OAJ27423.1 - 2.4e-18 65.4 0.0 4.4e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.14 OAJ27423.1 - 6.9e-08 32.6 1.0 6.7e-07 29.5 0.0 3.1 3 0 0 3 3 3 1 Transglutaminase-like superfamily BHD_2 PF10404.4 OAJ27423.1 - 0.016 15.4 0.3 0.016 15.4 0.2 3.5 4 1 0 4 4 4 0 Rad4 beta-hairpin domain 2 Mito_carr PF00153.22 OAJ27424.1 - 4e-44 148.2 9.7 3.5e-16 58.6 0.5 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF508 PF04370.7 OAJ27424.1 - 0.52 9.9 2.9 0.87 9.1 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) EBP PF05241.7 OAJ27426.1 - 2.9e-56 189.5 8.7 3.5e-56 189.3 6.1 1.0 1 0 0 1 1 1 1 Emopamil binding protein NAD_binding_8 PF13450.1 OAJ27426.1 - 0.0051 16.8 0.1 0.013 15.4 0.0 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HR_lesion PF05514.6 OAJ27426.1 - 0.082 12.7 2.2 0.64 9.8 0.1 2.4 2 0 0 2 2 2 0 HR-like lesion-inducing Glyco_transf_20 PF00982.16 OAJ27427.1 - 4.2e-137 457.4 0.0 5.2e-137 457.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 OAJ27427.1 - 0.0069 15.8 0.1 2.2 7.6 0.0 2.7 2 1 0 2 2 2 2 Glycosyl transferases group 1 Sedlin_N PF04628.8 OAJ27428.1 - 4.2e-37 126.9 0.0 8.4e-37 125.9 0.0 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 OAJ27428.1 - 3e-05 23.7 0.0 4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sporozoite_P67 PF05642.6 OAJ27428.1 - 0.56 8.0 6.1 0.65 7.7 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_Rpb1_5 PF04998.12 OAJ27430.1 - 3.8e-104 347.8 0.1 5.2e-104 347.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.9 OAJ27430.1 - 4.7e-61 205.8 0.2 7.9e-61 205.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_2 PF00623.15 OAJ27430.1 - 1.2e-46 158.6 0.0 2.7e-46 157.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 OAJ27430.1 - 1.6e-45 154.6 0.0 3.4e-45 153.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 OAJ27430.1 - 3.2e-42 143.4 0.5 6.9e-42 142.3 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 OAJ27430.1 - 1.5e-36 124.3 0.1 3.5e-36 123.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 OAJ27430.1 - 7.2e-21 72.4 234.8 0.012 15.6 6.5 15.7 10 1 6 18 18 18 17 RNA polymerase Rpb1 C-terminal repeat Evr1_Alr PF04777.8 OAJ27431.1 - 1.1e-28 98.8 0.2 1.7e-28 98.3 0.1 1.3 1 0 0 1 1 1 1 Erv1 / Alr family DUF4585 PF15232.1 OAJ27431.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) Phage_integrase PF00589.17 OAJ27432.1 - 0.0016 18.1 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Gemin6 PF06372.7 OAJ27432.1 - 0.16 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Gemin6 protein RNase_H PF00075.19 OAJ27433.1 - 0.00012 22.3 0.0 0.00022 21.5 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAJ27433.1 - 0.028 14.2 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Gemini_AL1 PF00799.15 OAJ27433.1 - 0.23 11.3 0.0 0.46 10.3 0.0 1.5 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain IF-2B PF01008.12 OAJ27434.1 - 5.9e-61 205.9 0.0 8.1e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Sugar_tr PF00083.19 OAJ27435.1 - 5.6e-84 282.3 22.0 6.4e-84 282.1 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ27435.1 - 1.3e-27 96.4 22.8 1.3e-27 96.4 15.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAJ27435.1 - 0.00023 19.4 0.5 0.00047 18.5 0.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4227 PF14004.1 OAJ27435.1 - 1.9 8.4 3.9 21 5.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) NAGLU PF05089.7 OAJ27436.1 - 0.058 12.1 0.1 0.092 11.4 0.1 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain Seryl_tRNA_N PF02403.17 OAJ27436.1 - 3.3 7.7 7.0 1.5 8.8 0.1 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DDE_3 PF13358.1 OAJ27437.1 - 1.4e-32 112.4 0.0 2.3e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAJ27437.1 - 6.2e-08 33.3 0.0 1.8e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 OAJ27437.1 - 1.4e-07 31.5 0.0 3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix DDE_1 PF03184.14 OAJ27437.1 - 4.7e-06 25.9 0.0 8.1e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 OAJ27437.1 - 1.1e-05 25.2 0.3 0.0014 18.5 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 OAJ27437.1 - 0.00033 20.6 0.0 0.0019 18.2 0.0 2.1 2 0 0 2 2 2 1 Transposase HTH_33 PF13592.1 OAJ27437.1 - 0.00055 19.4 0.7 0.0017 17.8 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix rve PF00665.21 OAJ27437.1 - 0.0021 18.1 0.0 0.0072 16.4 0.0 2.0 1 1 0 1 1 1 1 Integrase core domain HTH_23 PF13384.1 OAJ27437.1 - 0.0027 17.2 0.0 0.12 12.0 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain DDE_Tnp_ISAZ013 PF07592.6 OAJ27437.1 - 0.062 12.0 0.0 6.8 5.3 0.0 2.1 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain Myotub-related PF06602.9 OAJ27438.1 - 5.7e-121 403.6 0.0 3.4e-66 223.4 0.0 2.1 2 0 0 2 2 2 2 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 OAJ27438.1 - 0.038 14.2 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 OAJ27438.1 - 0.075 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase adh_short PF00106.20 OAJ27440.1 - 2.7e-11 43.6 8.1 9.1e-07 28.9 1.9 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 OAJ27440.1 - 2.9e-06 27.0 5.1 4.5e-05 23.1 0.7 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 OAJ27440.1 - 0.0014 18.4 0.7 0.33 10.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase RNA_polI_A34 PF08208.6 OAJ27441.1 - 0.021 14.5 45.9 6e+02 -0.1 31.8 3.1 1 1 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 BMF PF15185.1 OAJ27441.1 - 0.41 9.8 9.6 0.036 13.3 0.4 2.4 2 1 0 2 2 2 0 Bcl-2-modifying factor, apoptosis ABC_membrane PF00664.18 OAJ27442.1 - 6.1e-47 160.3 1.5 7.9e-47 159.9 1.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ27442.1 - 1.4e-31 109.6 0.0 4.2e-31 108.0 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 OAJ27442.1 - 0.00018 21.5 0.0 0.037 14.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ27442.1 - 0.00031 20.7 0.1 0.0016 18.4 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 OAJ27442.1 - 0.0014 17.9 0.6 0.041 13.0 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF637 PF04830.8 OAJ27442.1 - 0.0024 17.5 0.2 0.0075 15.9 0.1 1.8 1 0 0 1 1 1 1 Possible hemagglutinin (DUF637) AAA PF00004.24 OAJ27442.1 - 0.0049 17.0 0.0 0.084 13.0 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ27442.1 - 0.0065 16.6 0.1 0.046 13.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 OAJ27442.1 - 0.0069 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 OAJ27442.1 - 0.012 14.2 0.0 0.02 13.4 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_5 PF07728.9 OAJ27442.1 - 0.035 13.8 0.0 0.63 9.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 OAJ27442.1 - 0.055 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 OAJ27442.1 - 0.081 12.0 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 OAJ27442.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Peptidase_M28 PF04389.12 OAJ27443.1 - 1.1e-32 113.2 0.0 1.9e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 CCER1 PF15482.1 OAJ27444.1 - 0.0027 17.3 0.6 0.0029 17.2 0.4 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing glutamate-rich protein family 1 DUF1418 PF07214.7 OAJ27444.1 - 0.061 12.9 0.2 0.061 12.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) SCIMP PF15050.1 OAJ27444.1 - 0.15 11.9 1.3 0.18 11.6 0.4 1.5 1 1 0 1 1 1 0 SCIMP protein DUF605 PF04652.11 OAJ27444.1 - 0.82 8.9 25.0 0.92 8.8 17.4 1.0 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 OAJ27444.1 - 1.7 8.4 12.3 2 8.2 8.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hydrolase_6 PF13344.1 OAJ27445.1 - 7.4e-29 99.6 0.0 1.5e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAJ27445.1 - 2.1e-15 56.1 0.1 4e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 OAJ27445.1 - 1.3e-11 45.3 0.0 5.4e-11 43.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 OAJ27445.1 - 5.1e-05 23.5 0.0 0.026 14.7 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 OAJ27445.1 - 0.014 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) PGP_phosphatase PF09419.5 OAJ27445.1 - 0.058 12.7 0.0 0.26 10.6 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase DUF2346 PF09803.4 OAJ27446.1 - 7.1e-09 35.4 0.0 1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) SR-25 PF10500.4 OAJ27446.1 - 0.031 13.7 6.1 0.037 13.4 4.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CLN3 PF02487.12 OAJ27447.1 - 2.3e-64 217.7 10.6 9.2e-28 97.1 0.0 4.0 3 1 1 4 4 4 4 CLN3 protein PI3K_1B_p101 PF10486.4 OAJ27447.1 - 0.016 12.8 0.4 0.023 12.3 0.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nucleoplasmin PF03066.10 OAJ27447.1 - 0.24 10.8 6.5 1.2 8.6 3.8 2.1 2 0 0 2 2 2 0 Nucleoplasmin BSP_II PF05432.6 OAJ27447.1 - 0.32 10.2 8.1 0.48 9.6 5.6 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) NOA36 PF06524.7 OAJ27447.1 - 3 7.0 5.2 6.1 6.0 3.6 1.4 1 0 0 1 1 1 0 NOA36 protein Fcf1 PF04900.7 OAJ27448.1 - 8.2e-39 131.7 0.5 1.2e-38 131.2 0.4 1.3 1 0 0 1 1 1 1 Fcf1 UreD PF01774.12 OAJ27449.1 - 2e-49 167.9 0.0 7.6e-49 166.0 0.0 1.9 1 1 0 1 1 1 1 UreD urease accessory protein Tannase PF07519.6 OAJ27450.1 - 5.7e-72 242.9 0.0 1.6e-64 218.3 0.0 2.8 2 1 0 2 2 2 2 Tannase and feruloyl esterase GATA PF00320.22 OAJ27451.1 - 1.9e-15 55.8 6.0 4.6e-15 54.6 4.2 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 OAJ27451.1 - 0.0027 17.7 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold LRR_4 PF12799.2 OAJ27452.1 - 2.3e-18 65.3 18.8 1.4e-07 30.9 4.7 5.6 3 2 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ27452.1 - 3e-18 65.2 15.5 4.2e-08 32.8 6.9 4.1 3 1 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 OAJ27452.1 - 8.1e-09 34.3 16.5 0.93 9.7 0.6 7.6 6 1 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 OAJ27452.1 - 2.8e-07 29.9 19.3 1.3 9.2 0.4 7.5 6 1 1 7 7 7 3 Leucine Rich repeat zf-CCCH PF00642.19 OAJ27452.1 - 4.2e-06 26.3 7.2 0.0027 17.3 0.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_7 PF13504.1 OAJ27452.1 - 0.0024 17.7 20.7 5.8 7.5 0.1 7.4 6 1 1 7 7 7 2 Leucine rich repeat Pyr_redox_3 PF13738.1 OAJ27453.1 - 3.3e-22 79.5 0.1 2.2e-21 76.8 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAJ27453.1 - 3.3e-21 75.0 0.0 9.2e-21 73.6 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 OAJ27453.1 - 3.6e-11 43.3 1.8 3.5e-06 27.0 0.2 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ27453.1 - 7.2e-10 38.3 0.4 4.5e-07 29.1 0.0 2.8 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAJ27453.1 - 2.5e-09 37.0 1.1 1.3e-07 31.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ27453.1 - 6.1e-08 31.9 0.9 4.3e-06 25.8 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAJ27453.1 - 1.2e-05 25.5 3.3 0.04 14.3 0.4 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ27453.1 - 1.2e-05 25.1 5.3 0.0033 17.1 0.1 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding HI0933_like PF03486.9 OAJ27453.1 - 3.2e-05 22.6 0.2 0.03 12.7 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein AlaDh_PNT_C PF01262.16 OAJ27453.1 - 0.00021 20.9 1.3 0.048 13.2 0.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 OAJ27453.1 - 0.00027 20.1 3.1 0.041 12.9 0.2 2.5 3 0 0 3 3 3 2 Thi4 family Shikimate_DH PF01488.15 OAJ27453.1 - 0.00041 20.4 0.2 0.45 10.6 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 OAJ27453.1 - 0.00059 20.0 0.0 0.15 12.3 0.0 2.6 3 0 0 3 3 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 OAJ27453.1 - 0.00095 18.8 0.4 0.00095 18.8 0.3 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 OAJ27453.1 - 0.018 14.4 0.8 0.018 14.4 0.6 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 OAJ27453.1 - 0.045 12.6 2.5 2.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 OAJ27453.1 - 0.069 12.1 1.6 0.53 9.2 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 OAJ27453.1 - 0.075 12.0 0.1 0.79 8.7 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ27453.1 - 0.086 11.6 7.0 0.057 12.2 0.3 2.4 3 0 0 3 3 3 0 FAD binding domain Abhydrolase_5 PF12695.2 OAJ27455.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 OAJ27455.1 - 0.099 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF4563 PF15124.1 OAJ27456.1 - 0.15 11.6 0.4 7.5 6.0 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4563) DUF2721 PF11026.3 OAJ27456.1 - 0.46 10.1 1.6 0.75 9.4 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) UPRTase PF14681.1 OAJ27458.1 - 6.6e-64 214.9 0.0 7.7e-64 214.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 OAJ27458.1 - 3.3e-08 33.2 0.0 5.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Ras PF00071.17 OAJ27459.1 - 7.6e-58 194.4 0.2 8.8e-58 194.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ27459.1 - 1.9e-18 67.0 0.0 2.7e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ27459.1 - 3.4e-08 32.9 0.0 4.2e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ27459.1 - 3.3e-06 26.6 0.0 6e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ27459.1 - 0.0061 16.5 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ27459.1 - 0.028 13.7 0.1 0.07 12.4 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_25 PF13481.1 OAJ27459.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sec23_trunk PF04811.10 OAJ27460.1 - 7e-76 254.7 0.0 1e-75 254.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 OAJ27460.1 - 1.2e-34 117.8 0.3 2.1e-34 117.0 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 OAJ27460.1 - 4.1e-31 107.3 0.0 7.6e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 OAJ27460.1 - 1.7e-16 59.4 5.4 3.1e-16 58.6 3.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 OAJ27460.1 - 7.8e-13 47.9 0.0 1.8e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat RF-1 PF00472.15 OAJ27461.1 - 1.9e-13 50.2 0.3 3.4e-13 49.4 0.2 1.4 1 0 0 1 1 1 1 RF-1 domain PNK3P PF08645.6 OAJ27462.1 - 1.4e-37 128.6 0.2 8.2e-21 74.0 0.0 2.4 2 0 0 2 2 2 2 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 OAJ27462.1 - 1.4e-25 89.8 0.0 1.7e-24 86.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAJ27462.1 - 3.6e-05 22.9 0.0 0.09 11.8 0.0 2.3 1 1 1 2 2 2 2 Zeta toxin AAA_17 PF13207.1 OAJ27462.1 - 0.015 16.1 0.0 0.42 11.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.5 OAJ27462.1 - 0.02 14.0 0.0 0.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_22 PF13401.1 OAJ27462.1 - 0.037 14.1 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain MUG113 PF13455.1 OAJ27463.1 - 6.9e-17 61.6 0.0 2.2e-16 60.0 0.0 1.9 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 OAJ27463.1 - 2.1e-09 37.6 0.0 1.5e-08 34.9 0.0 2.3 1 1 0 1 1 1 1 T5orf172 domain Aminotran_5 PF00266.14 OAJ27464.1 - 5.5e-31 107.6 0.1 1.2e-26 93.2 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 OAJ27464.1 - 1.5e-06 26.7 0.0 4.2e-06 25.3 0.0 1.9 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme HTH_9 PF08221.6 OAJ27464.1 - 0.099 12.5 0.1 4.9 7.0 0.0 2.8 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Glyco_transf_22 PF03901.12 OAJ27465.1 - 6e-83 279.1 12.4 2.3e-64 217.9 4.5 2.8 2 1 0 2 2 2 2 Alg9-like mannosyltransferase family PMT_2 PF13231.1 OAJ27465.1 - 1.4e-07 31.5 4.9 4.5e-07 29.9 3.4 1.8 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Cellulase PF00150.13 OAJ27466.1 - 4.3e-16 58.9 0.6 6.5e-16 58.3 0.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cyt-b5 PF00173.23 OAJ27467.1 - 2.9e-26 91.0 0.0 3.7e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Y_phosphatase2 PF03162.8 OAJ27468.1 - 1.2e-56 190.6 0.0 1.8e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 OAJ27468.1 - 9.7e-08 32.4 0.0 2.7e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 OAJ27468.1 - 0.00084 18.7 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 OAJ27468.1 - 0.0077 15.8 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain WD40 PF00400.27 OAJ27469.1 - 1.7e-14 53.0 0.5 2.9e-08 33.2 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat BRCT PF00533.21 OAJ27470.1 - 1.1e-07 31.9 0.0 2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 OAJ27470.1 - 2.2e-06 27.3 0.0 5.3e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.3 OAJ27470.1 - 0.00011 21.9 0.0 0.00022 20.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.16 OAJ27470.1 - 0.00063 19.8 0.1 0.0018 18.3 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Myc_N PF01056.13 OAJ27470.1 - 0.032 13.3 4.6 0.056 12.6 3.2 1.4 1 0 0 1 1 1 0 Myc amino-terminal region dCMP_cyt_deam_1 PF00383.17 OAJ27471.1 - 6.2e-20 70.7 0.1 1.1e-19 69.9 0.0 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 OAJ27471.1 - 2e-05 24.4 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Bd3614-like deaminase Ima1_N PF09779.4 OAJ27472.1 - 2.1 8.8 5.5 8.1 6.9 0.2 2.8 2 0 0 2 2 2 0 Ima1 N-terminal domain DDHD PF02862.12 OAJ27475.1 - 2.9e-28 99.2 0.0 2.9e-28 99.2 0.0 3.8 3 2 0 3 3 3 2 DDHD domain Tetraspannin PF00335.15 OAJ27476.1 - 1.4e-05 24.4 6.1 2e-05 24.0 1.2 2.1 1 1 1 2 2 2 1 Tetraspanin family Shisa PF13908.1 OAJ27476.1 - 0.002 18.3 0.0 0.0062 16.7 0.0 1.8 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator COX15-CtaA PF02628.10 OAJ27476.1 - 0.04 12.7 2.7 0.062 12.1 0.9 1.8 2 0 0 2 2 2 0 Cytochrome oxidase assembly protein DsbB PF02600.11 OAJ27476.1 - 0.052 13.3 5.7 0.033 13.9 1.7 1.9 2 0 0 2 2 2 0 Disulfide bond formation protein DsbB Claudin_2 PF13903.1 OAJ27476.1 - 0.057 13.1 2.5 0.37 10.4 0.2 2.4 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2207 PF09972.4 OAJ27476.1 - 0.098 11.2 1.1 1.2 7.6 0.0 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF3040 PF11239.3 OAJ27476.1 - 1.8 8.6 6.7 9.6 6.3 1.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) zf-HIT PF04438.11 OAJ27477.1 - 5.6e-09 35.4 10.3 7.9e-09 35.0 7.1 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.19 OAJ27477.1 - 0.14 12.1 4.8 0.22 11.4 3.3 1.3 1 0 0 1 1 1 0 B-box zinc finger CM_2 PF01817.16 OAJ27478.1 - 0.085 12.9 0.0 11 6.1 0.0 2.5 2 1 0 2 2 2 0 Chorismate mutase type II CDP-OH_P_transf PF01066.16 OAJ27479.1 - 1.9e-11 44.1 1.4 4.2e-11 43.0 1.0 1.6 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.20 OAJ27480.1 - 4.4e-56 189.9 0.0 6.8e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ27480.1 - 1.9e-20 73.0 0.0 9.9e-20 70.6 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase TIP49 PF06068.8 OAJ27481.1 - 1.1e-172 574.2 0.2 1.3e-172 574.0 0.2 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 OAJ27481.1 - 4.1e-12 46.4 0.7 2.7e-09 37.3 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 OAJ27481.1 - 6.7e-12 44.9 0.8 9.4e-09 34.6 0.0 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 OAJ27481.1 - 3e-08 33.8 0.0 1.3e-07 31.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ27481.1 - 1.8e-07 31.3 0.1 0.0058 16.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain DnaB_C PF03796.10 OAJ27481.1 - 6.1e-06 25.3 0.2 1.1e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_5 PF07728.9 OAJ27481.1 - 7e-06 25.8 0.2 0.0033 17.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 OAJ27481.1 - 1.1e-05 24.6 0.7 0.00045 19.4 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 OAJ27481.1 - 4.8e-05 22.9 0.0 0.062 12.7 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 OAJ27481.1 - 7.6e-05 22.3 0.0 0.00029 20.5 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 OAJ27481.1 - 0.00014 21.3 0.2 0.00039 19.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ27481.1 - 0.00015 22.5 0.1 0.00088 20.0 0.0 2.2 2 2 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 OAJ27481.1 - 0.00037 19.9 0.0 0.00077 18.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 OAJ27481.1 - 0.0005 19.9 0.0 1.1 9.2 0.0 3.3 4 0 0 4 4 3 1 AAA domain Parvo_NS1 PF01057.12 OAJ27481.1 - 0.00057 18.8 0.0 0.00087 18.2 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.7 OAJ27481.1 - 0.0009 18.3 0.1 0.0018 17.4 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 OAJ27481.1 - 0.0019 17.8 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 OAJ27481.1 - 0.0021 18.3 0.3 0.0089 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAJ27481.1 - 0.0072 16.1 0.0 0.021 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAJ27481.1 - 0.0073 15.9 0.1 0.012 15.1 0.1 1.4 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 OAJ27481.1 - 0.01 14.8 0.2 0.026 13.5 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 OAJ27481.1 - 0.014 14.6 0.1 0.034 13.3 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 OAJ27481.1 - 0.014 14.9 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 OAJ27481.1 - 0.016 15.5 0.1 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 OAJ27481.1 - 0.018 14.0 0.6 0.74 8.6 0.1 2.2 2 0 0 2 2 2 0 PIF1-like helicase ResIII PF04851.10 OAJ27481.1 - 0.024 14.4 0.2 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 OAJ27481.1 - 0.025 14.5 0.5 0.053 13.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_2 PF07724.9 OAJ27481.1 - 0.029 14.2 0.1 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 OAJ27481.1 - 0.04 13.9 0.0 0.53 10.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain T2SE PF00437.15 OAJ27481.1 - 0.045 12.6 1.7 0.12 11.1 0.1 2.2 1 1 1 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.17 OAJ27481.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 OAJ27481.1 - 0.067 12.7 0.5 1.1 8.8 0.0 2.6 3 0 0 3 3 2 0 P-loop containing region of AAA domain APS_kinase PF01583.15 OAJ27481.1 - 0.081 12.5 0.2 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase NTPase_1 PF03266.10 OAJ27481.1 - 0.1 12.2 1.9 0.38 10.4 0.3 2.5 2 1 0 2 2 2 0 NTPase Sipho_tail PF05709.6 OAJ27481.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Phage tail protein ACC_central PF08326.7 OAJ27482.1 - 1.9e-186 621.3 0.0 2.8e-186 620.7 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 OAJ27482.1 - 2.6e-160 534.0 0.0 3.5e-160 533.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 OAJ27482.1 - 1.4e-52 178.0 0.0 3e-52 176.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 OAJ27482.1 - 2.3e-24 85.6 0.1 5.5e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 OAJ27482.1 - 1.1e-21 76.8 0.0 3e-20 72.1 0.0 3.0 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 OAJ27482.1 - 1.3e-14 53.5 0.2 2.5e-14 52.6 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 OAJ27482.1 - 2e-12 47.2 0.0 7.5e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 OAJ27482.1 - 3.9e-06 26.4 0.0 1.3e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp PF02222.17 OAJ27482.1 - 0.00082 18.7 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.1 OAJ27482.1 - 0.0027 17.3 0.0 0.0078 15.9 0.0 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain ATP-grasp_3 PF02655.9 OAJ27482.1 - 0.013 15.4 0.0 0.046 13.5 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain Dala_Dala_lig_C PF07478.8 OAJ27482.1 - 0.025 13.9 0.0 0.061 12.7 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus RimK PF08443.6 OAJ27482.1 - 0.08 12.4 0.0 1.5 8.2 0.0 2.6 2 1 0 2 2 2 0 RimK-like ATP-grasp domain HlyD_2 PF12700.2 OAJ27482.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein SEP PF08059.8 OAJ27483.1 - 8e-19 67.7 0.0 1.5e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 OAJ27483.1 - 3.4e-13 49.4 0.0 5.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 OAJ27483.1 - 2.1e-09 36.7 1.5 3.6e-09 36.0 1.1 1.4 1 0 0 1 1 1 1 UBA-like domain SUR7 PF06687.7 OAJ27484.1 - 6.3e-21 74.9 13.3 8.1e-21 74.5 9.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family JAB PF01398.16 OAJ27485.1 - 1.2e-14 53.9 0.0 2.1e-13 50.0 0.0 2.3 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 OAJ27485.1 - 2.2e-09 37.3 0.0 4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function MGC-24 PF05283.6 OAJ27485.1 - 0.21 11.3 10.8 0.44 10.3 7.5 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DUF4349 PF14257.1 OAJ27485.1 - 5.5 6.1 14.4 0.44 9.7 0.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) LSM PF01423.17 OAJ27486.1 - 1.1e-20 72.9 0.3 1.3e-20 72.7 0.2 1.0 1 0 0 1 1 1 1 LSM domain Ribosomal_L16 PF00252.13 OAJ27487.1 - 5.7e-41 139.3 0.4 7.9e-41 138.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PX PF00787.19 OAJ27488.1 - 3.8e-13 49.2 0.0 7.3e-13 48.3 0.0 1.5 1 1 0 1 1 1 1 PX domain SNARE PF05739.14 OAJ27488.1 - 4.7e-08 32.6 1.0 6.7e-08 32.1 0.7 1.2 1 0 0 1 1 1 1 SNARE domain Med3 PF11593.3 OAJ27488.1 - 0.31 10.2 7.9 0.43 9.7 5.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Bap31 PF05529.7 OAJ27490.1 - 6.9e-54 182.2 8.4 8.5e-54 181.9 5.8 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like GrpE PF01025.14 OAJ27490.1 - 0.2 11.2 4.5 0.11 12.0 1.1 1.8 2 0 0 2 2 2 0 GrpE HMG_box PF00505.14 OAJ27490.1 - 0.25 11.6 2.0 0.43 10.8 1.4 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box SeleniumBinding PF11524.3 OAJ27490.1 - 0.26 11.4 2.3 18 5.5 0.1 2.7 1 1 2 3 3 3 0 Selenium binding protein HDAC4_Gln PF12203.3 OAJ27490.1 - 0.92 9.4 7.9 0.56 10.1 1.6 2.5 1 1 2 3 3 3 0 Glutamine rich N terminal domain of histone deacetylase 4 TFIIF_beta PF02270.10 OAJ27491.1 - 1.7e-11 44.4 0.0 2.2e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit SNARE PF05739.14 OAJ27492.1 - 0.0078 15.8 0.0 0.0095 15.6 0.0 1.1 1 0 0 1 1 1 1 SNARE domain V-SNARE_C PF12352.3 OAJ27492.1 - 0.09 12.8 0.3 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Peptidase_S8 PF00082.17 OAJ27493.1 - 1.2e-42 146.0 1.4 2e-42 145.2 1.0 1.3 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.3 OAJ27493.1 - 1.1e-38 132.5 0.0 1.6e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II Ribosomal_L37 PF08561.5 OAJ27494.1 - 9.5e-23 79.5 4.1 9.6e-21 73.1 2.9 2.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 Terminase_3 PF04466.8 OAJ27494.1 - 0.24 10.4 1.5 0.32 10.0 1.1 1.1 1 0 0 1 1 1 0 Phage terminase large subunit DUF4510 PF14971.1 OAJ27494.1 - 5 7.2 15.5 0.19 11.9 6.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4510) SHQ1 PF04925.10 OAJ27497.1 - 7.2e-25 87.5 0.0 1.4e-14 53.9 0.0 2.2 2 0 0 2 2 2 2 SHQ1 protein YuzL PF14115.1 OAJ27497.1 - 0.81 10.0 3.6 2.9 8.2 2.5 1.9 1 0 0 1 1 1 0 YuzL-like protein DASH_Hsk3 PF08227.6 OAJ27498.1 - 1.7e-05 24.9 1.7 2.4e-05 24.4 1.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like BAF1_ABF1 PF04684.8 OAJ27499.1 - 8 5.1 8.4 16 4.2 5.8 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Cys_Met_Meta_PP PF01053.15 OAJ27500.1 - 1.4e-95 319.8 0.0 1.6e-95 319.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 OAJ27500.1 - 5.4e-12 45.4 0.2 8e-12 44.8 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 OAJ27500.1 - 1.6e-10 40.4 0.1 2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 OAJ27500.1 - 2.2e-09 36.5 0.2 2.8e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 OAJ27500.1 - 3.2e-05 22.4 0.0 4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 OAJ27500.1 - 4.7e-05 22.6 0.1 0.00015 21.0 0.1 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 OAJ27500.1 - 0.12 11.0 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein SLA_LP_auto_ag PF05889.8 OAJ27500.1 - 0.19 10.1 0.1 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Aminotran_5 PF00266.14 OAJ27501.1 - 7.6e-90 301.3 0.0 1.1e-89 300.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MR_MLE_C PF13378.1 OAJ27501.1 - 0.016 15.1 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Enolase C-terminal domain-like Grp1_Fun34_YaaH PF01184.14 OAJ27502.1 - 1.3e-39 135.6 6.3 1.7e-39 135.2 4.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family IncA PF04156.9 OAJ27502.1 - 0.089 12.3 0.6 0.089 12.3 0.4 1.9 2 1 0 2 2 2 0 IncA protein RRM_1 PF00076.17 OAJ27503.1 - 5e-26 90.1 0.1 3e-12 45.9 0.0 5.2 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ27503.1 - 9.6e-17 60.7 0.0 1.4e-06 28.1 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ27503.1 - 2e-14 53.1 0.0 0.00023 20.9 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RhoGAP PF00620.22 OAJ27504.1 - 7.9e-38 129.4 0.1 1.8e-37 128.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 OAJ27504.1 - 2.3e-24 85.2 32.6 3.4e-10 39.8 4.7 5.1 5 0 0 5 5 5 4 LIM domain Ribosomal_L28e PF01778.12 OAJ27505.1 - 7.7e-27 94.0 0.4 3.1e-26 92.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 OAJ27505.1 - 1.4e-19 70.0 22.0 1.4e-19 70.0 15.3 3.4 2 1 1 3 3 3 2 Mak16 protein C-terminal region PYC_OADA PF02436.13 OAJ27505.1 - 0.06 12.7 0.6 0.13 11.6 0.4 1.6 1 0 0 1 1 1 0 Conserved carboxylase domain MSA_2 PF00985.12 OAJ27506.1 - 0.0022 18.1 0.5 0.0023 18.0 0.3 1.0 1 0 0 1 1 1 1 Merozoite Surface Antigen 2 (MSA-2) family CPSF73-100_C PF11718.3 OAJ27507.1 - 8.1e-47 159.3 2.8 8.4e-45 152.7 0.5 3.3 3 1 0 3 3 3 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 OAJ27507.1 - 4.9e-31 107.2 0.0 9.4e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 OAJ27507.1 - 1e-13 51.3 1.0 1e-13 51.3 0.7 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 OAJ27507.1 - 3.9e-11 42.5 0.1 7.8e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 OAJ27507.1 - 1.3e-09 37.9 0.3 1.3e-09 37.9 0.2 2.2 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 OAJ27507.1 - 2.3e-06 27.4 0.1 1.1e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Thg1 PF04446.7 OAJ27509.1 - 5.8e-44 148.9 0.0 8.3e-44 148.4 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 OAJ27509.1 - 2.6e-43 146.5 0.0 4.1e-43 145.9 0.0 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain cNMP_binding PF00027.24 OAJ27510.1 - 6.7e-37 125.1 0.0 5.2e-17 61.4 0.0 5.5 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.17 OAJ27510.1 - 1.4e-17 64.3 7.9 3.8e-16 59.6 4.0 3.3 2 1 0 2 2 2 1 Patatin-like phospholipase Transposase_21 PF02992.9 OAJ27512.1 - 0.006 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Ribonuclease_3 PF00636.21 OAJ27513.1 - 5.4e-10 39.7 0.0 7.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 OAJ27513.1 - 0.0012 18.7 0.1 0.0024 17.8 0.0 1.4 2 0 0 2 2 2 1 Ribonuclease-III-like Peptidase_S8 PF00082.17 OAJ27514.1 - 1.9e-42 145.3 4.6 1e-41 143.0 3.2 2.1 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 OAJ27514.1 - 2.6e-13 50.3 1.3 5.2e-13 49.3 0.0 2.3 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) PA PF02225.17 OAJ27514.1 - 0.0059 16.2 0.0 0.016 14.8 0.0 1.8 1 0 0 1 1 1 1 PA domain DPBB_1 PF03330.13 OAJ27515.1 - 0.00025 20.9 1.0 0.00086 19.2 0.7 2.0 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ27515.1 - 0.00047 19.8 0.1 0.0007 19.2 0.1 1.3 1 0 0 1 1 1 1 Barwin family Glycogen_syn PF05693.8 OAJ27517.1 - 0 1116.3 0.0 0 1116.0 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 OAJ27517.1 - 8.9e-09 34.9 0.0 7.4e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 OAJ27517.1 - 6.6e-07 29.0 0.1 1.7e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 OAJ27517.1 - 1.3e-05 25.4 0.0 2.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Caleosin PF05042.8 OAJ27518.1 - 1.3e-49 168.0 0.0 1.8e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein Rap_GAP PF02145.10 OAJ27519.1 - 1.1e-47 161.8 0.0 1.7e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP DUF3384 PF11864.3 OAJ27519.1 - 1.6e-39 135.7 0.0 2.4e-38 131.8 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3384) Tuberin PF03542.11 OAJ27519.1 - 5.1e-26 91.5 5.7 3e-24 85.7 3.3 2.9 2 1 0 2 2 2 1 Tuberin rve PF00665.21 OAJ27521.1 - 1.1e-06 28.7 0.2 2.6e-06 27.5 0.1 1.7 2 0 0 2 2 2 1 Integrase core domain CPSase_L_D3 PF02787.14 OAJ27521.1 - 0.15 11.8 0.1 0.48 10.1 0.0 1.9 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Helitron_like_N PF14214.1 OAJ27523.1 - 1e-08 35.1 0.0 1.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF883 PF05957.8 OAJ27524.1 - 0.00076 19.8 1.6 0.32 11.4 0.3 2.3 1 1 0 2 2 2 2 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 OAJ27524.1 - 0.012 15.1 1.9 0.063 12.7 1.3 1.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain FliT PF05400.8 OAJ27524.1 - 0.037 14.4 1.0 0.24 11.8 0.7 2.2 1 1 0 1 1 1 0 Flagellar protein FliT Erp_C PF06780.6 OAJ27524.1 - 0.051 13.4 0.1 12 5.6 0.0 2.7 2 1 1 3 3 3 0 Erp protein C-terminus DUF2316 PF10078.4 OAJ27524.1 - 0.053 13.5 0.6 0.83 9.6 0.1 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) cwf21 PF08312.7 OAJ27524.1 - 0.16 11.8 1.2 1.6 8.6 0.5 2.3 2 0 0 2 2 2 0 cwf21 domain Fzo_mitofusin PF04799.8 OAJ27524.1 - 0.5 9.7 2.6 9.3 5.5 0.3 2.3 1 1 1 2 2 2 0 fzo-like conserved region DUF4164 PF13747.1 OAJ27524.1 - 0.51 10.5 3.7 0.86 9.7 0.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Mst1_SARAH PF11629.3 OAJ27524.1 - 0.55 10.1 3.1 9.1 6.1 0.2 2.4 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 KfrA_N PF11740.3 OAJ27524.1 - 0.59 10.5 3.8 0.88 10.0 0.2 2.6 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term FA_hydroxylase PF04116.8 OAJ27526.1 - 5.1e-15 55.8 16.5 5.1e-15 55.8 11.4 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_S6 PF01250.12 OAJ27527.1 - 5.4e-14 51.8 0.0 6.7e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 UQ_con PF00179.21 OAJ27528.1 - 1.2e-20 73.3 0.0 2.1e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 OAJ27528.1 - 0.019 14.8 0.0 0.049 13.5 0.0 1.7 1 0 0 1 1 1 0 RWD domain zf-4CXXC_R1 PF10497.4 OAJ27528.1 - 0.038 14.1 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 CLTH PF10607.4 OAJ27529.1 - 1.5e-20 73.3 0.0 2.4e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 OAJ27529.1 - 0.013 15.2 0.2 0.035 13.8 0.2 1.8 1 0 0 1 1 1 0 LisH rve PF00665.21 OAJ27533.1 - 2.9e-07 30.6 0.0 5.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Alg14 PF08660.6 OAJ27534.1 - 7e-45 153.0 0.0 2.2e-44 151.4 0.0 1.7 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DUF1639 PF07797.9 OAJ27534.1 - 5.2 6.5 6.4 19 4.7 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) SHS2_Rpb7-N PF03876.12 OAJ27535.1 - 3.1e-06 27.2 0.0 6.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 YL1 PF05764.8 OAJ27535.1 - 0.0099 15.5 19.1 0.0099 15.5 13.2 2.3 2 0 0 2 2 2 1 YL1 nuclear protein Cwf_Cwc_15 PF04889.7 OAJ27535.1 - 1.9 8.1 29.4 0.054 13.2 14.5 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Glypican PF01153.14 OAJ27535.1 - 5 5.6 10.0 9.6 4.6 6.9 1.4 1 0 0 1 1 1 0 Glypican Chitin_synth_2 PF03142.10 OAJ27536.1 - 8.6e-234 776.8 0.0 1.2e-233 776.3 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 OAJ27536.1 - 6e-14 52.1 9.9 6e-14 52.1 6.9 2.8 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ27536.1 - 6e-13 49.1 0.1 1.7e-11 44.3 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 OAJ27536.1 - 0.0022 17.7 0.1 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 OAJ27536.1 - 0.047 13.3 0.0 0.92 9.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Tom5 PF10642.4 OAJ27537.1 - 0.39 10.3 3.5 0.55 9.9 2.4 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase TALPID3 PF15324.1 OAJ27537.1 - 0.43 7.8 2.7 0.38 8.0 1.8 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Atg14 PF10186.4 OAJ27538.1 - 6.2e-16 58.2 3.2 1e-15 57.5 2.2 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 ALO PF04030.9 OAJ27538.1 - 0.039 13.5 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase DUF202 PF02656.10 OAJ27539.1 - 4.8e-05 23.4 5.0 0.00017 21.7 2.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Baculo_E56 PF04639.7 OAJ27539.1 - 0.028 13.0 0.1 0.039 12.6 0.1 1.2 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope Shisa PF13908.1 OAJ27539.1 - 0.57 10.3 5.4 0.18 11.9 0.1 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Gly-zipper_OmpA PF13436.1 OAJ27540.1 - 0.0039 16.8 0.6 0.0062 16.1 0.4 1.4 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain PRP1_N PF06424.7 OAJ27540.1 - 0.1 12.9 0.2 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Tom5 PF10642.4 OAJ27540.1 - 0.96 9.1 4.9 0.22 11.1 0.6 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase zf-C2H2_4 PF13894.1 OAJ27541.1 - 0.5 10.8 0.1 0.5 10.8 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 OAJ27541.1 - 0.61 10.5 0.0 0.61 10.5 0.0 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type TPR_MLP1_2 PF07926.7 OAJ27542.1 - 2.2e-23 82.4 16.3 2.2e-23 82.4 11.3 19.3 8 5 10 18 18 18 4 TPR/MLP1/MLP2-like protein GRASP55_65 PF04495.9 OAJ27543.1 - 5e-60 201.4 0.0 6.7e-49 165.4 0.0 2.3 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 OAJ27543.1 - 0.097 12.5 0.0 41 4.1 0.0 3.4 3 1 0 3 3 3 0 PDZ domain Myc_N PF01056.13 OAJ27543.1 - 0.12 11.5 3.9 0.18 10.9 2.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_60s PF00428.14 OAJ27543.1 - 1.1 9.7 12.3 0.077 13.4 3.5 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPR_11 PF13414.1 OAJ27545.1 - 1e-47 159.6 33.1 3.3e-13 49.0 4.9 7.5 3 3 5 8 8 8 8 TPR repeat TPR_2 PF07719.12 OAJ27545.1 - 3.9e-30 101.3 21.6 1.9e-05 24.2 0.0 11.0 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ27545.1 - 7.6e-30 101.2 20.9 2e-06 27.1 0.8 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ27545.1 - 2.6e-27 94.8 12.8 3.4e-07 30.7 0.0 6.4 4 2 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ27545.1 - 7.1e-23 78.8 14.0 1.4e-05 24.8 0.0 9.2 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ27545.1 - 4.1e-20 71.5 18.4 5e-06 26.3 0.0 7.1 3 2 7 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ27545.1 - 5.1e-15 54.0 16.8 0.0016 18.1 0.2 8.8 8 2 1 9 9 8 4 Tetratricopeptide repeat Apc3 PF12895.2 OAJ27545.1 - 8e-15 54.7 11.5 0.00018 21.5 0.1 5.0 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 OAJ27545.1 - 5.1e-14 51.5 16.6 0.002 18.6 0.0 9.2 4 4 6 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ27545.1 - 3.3e-13 49.7 19.5 0.00024 21.3 0.0 6.2 4 1 3 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ27545.1 - 2e-09 37.1 11.9 1.5e-05 24.7 0.1 5.5 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ27545.1 - 3.6e-07 29.4 16.7 0.44 10.4 0.0 7.7 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 OAJ27545.1 - 1.5e-05 24.1 11.4 0.021 13.9 1.4 4.3 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ27545.1 - 7.9e-05 22.7 11.2 0.036 14.1 0.0 5.5 3 2 4 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ27545.1 - 0.00097 19.4 23.6 0.44 11.1 0.0 8.1 10 0 0 10 10 6 3 Tetratricopeptide repeat DUF3856 PF12968.2 OAJ27545.1 - 0.012 15.4 11.1 0.35 10.6 0.0 5.4 4 2 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.9 OAJ27545.1 - 0.016 15.6 1.2 20 5.9 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 OAJ27545.1 - 0.059 13.1 0.3 1.6 8.5 0.0 3.2 4 0 0 4 4 3 0 Rapsyn N-terminal myristoylation and linker region TPR_10 PF13374.1 OAJ27545.1 - 0.16 11.9 17.0 6.2 6.8 0.0 7.2 6 1 1 7 7 7 0 Tetratricopeptide repeat Methyltransf_2 PF00891.13 OAJ27546.1 - 8.2e-31 107.0 0.0 9.4e-28 97.0 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase Methyltransf_18 PF12847.2 OAJ27546.1 - 0.0028 18.2 0.0 0.0061 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Rrf2 PF02082.15 OAJ27546.1 - 0.015 15.3 0.0 5.6 7.1 0.0 2.9 3 0 0 3 3 3 0 Transcriptional regulator tRNA-synt_2c PF01411.14 OAJ27550.1 - 6.9e-210 698.0 0.0 1.1e-209 697.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 OAJ27550.1 - 9.7e-17 60.5 0.1 2.3e-16 59.3 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain cobW PF02492.14 OAJ27552.1 - 1.4e-42 145.1 4.9 2.1e-41 141.3 3.4 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 OAJ27552.1 - 6.6e-18 64.2 0.2 1.5e-12 47.0 0.0 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain CDC45 PF02724.9 OAJ27552.1 - 0.0059 14.7 1.6 0.0086 14.1 1.1 1.2 1 0 0 1 1 1 1 CDC45-like protein AAA_22 PF13401.1 OAJ27552.1 - 0.021 14.9 0.7 0.18 11.9 0.4 2.5 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 OAJ27552.1 - 0.027 13.9 0.0 0.077 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 OAJ27552.1 - 0.039 13.5 0.1 0.081 12.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 OAJ27552.1 - 0.056 13.3 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 OAJ27552.1 - 0.057 12.9 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PEPCK_ATP PF01293.15 OAJ27552.1 - 0.099 11.1 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 OAJ27552.1 - 0.11 12.0 0.2 0.26 10.8 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 OAJ27552.1 - 0.19 12.0 3.5 2.8 8.2 2.4 2.8 1 1 0 1 1 1 0 AAA domain Nop14 PF04147.7 OAJ27552.1 - 0.26 9.1 6.9 0.4 8.5 4.8 1.2 1 0 0 1 1 1 0 Nop14-like family AAA_16 PF13191.1 OAJ27552.1 - 0.93 9.4 4.3 1.9 8.4 0.2 2.8 3 1 0 3 3 3 0 AAA ATPase domain DUF2890 PF11081.3 OAJ27552.1 - 1.4 8.9 5.4 0.35 10.8 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) DUF2457 PF10446.4 OAJ27552.1 - 10 4.7 14.1 19 3.8 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_N PF01194.12 OAJ27553.1 - 1.7e-26 92.0 0.3 2.2e-26 91.6 0.2 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Pkinase PF00069.20 OAJ27554.1 - 5.8e-56 189.5 0.0 7e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ27554.1 - 3.5e-38 131.1 0.0 4.6e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ27554.1 - 4.2e-07 29.2 0.0 1.1e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAJ27554.1 - 0.016 14.9 0.0 0.13 11.9 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family PAPS_reduct PF01507.14 OAJ27555.1 - 3e-20 72.7 0.0 5.3e-15 55.6 0.0 2.6 2 1 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family DUF2235 PF09994.4 OAJ27556.1 - 5.9e-57 193.1 0.0 9.8e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.4 OAJ27557.1 - 5e-56 190.1 0.0 4.8e-55 186.8 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 OAJ27557.1 - 0.003 17.3 0.1 0.0059 16.3 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hormone_recep PF00104.25 OAJ27557.1 - 0.032 13.3 0.0 0.64 9.1 0.0 2.2 2 0 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor Tim17 PF02466.14 OAJ27558.1 - 1.8e-20 73.2 9.4 2.8e-20 72.6 6.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PRCC PF10253.4 OAJ27558.1 - 3.7 8.2 11.9 4.9 7.8 8.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF2235 PF09994.4 OAJ27559.1 - 1.3e-65 221.5 0.0 1.8e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 OAJ27559.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.20 OAJ27560.1 - 2.3e-74 249.8 0.1 2.3e-74 249.8 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ27560.1 - 5.2e-53 179.7 1.1 1.4e-52 178.3 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 OAJ27560.1 - 7e-21 74.4 0.1 3.9e-20 72.0 0.0 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.24 OAJ27560.1 - 7.1e-10 39.0 1.4 1.5e-09 38.0 1.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 OAJ27560.1 - 9.5e-07 28.0 0.0 1.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 OAJ27560.1 - 0.00049 20.3 0.7 0.046 13.9 0.5 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 OAJ27560.1 - 0.0039 16.9 4.1 0.01 15.6 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1777 PF08648.7 OAJ27560.1 - 0.0061 16.3 7.9 0.015 15.0 5.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Rotamase PF00639.16 OAJ27560.1 - 1.6 9.5 7.1 4.3 8.1 4.9 1.8 1 0 0 1 1 1 0 PPIC-type PPIASE domain DUF2514 PF10721.4 OAJ27560.1 - 5.8 6.5 28.6 12 5.5 19.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Glyco_hydro_32N PF00251.15 OAJ27561.1 - 4.4e-38 131.3 0.0 2.1e-36 125.8 0.0 2.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 OAJ27561.1 - 8.4e-11 42.1 0.0 1.8e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal TPR_1 PF00515.23 OAJ27564.1 - 9.4e-58 189.6 14.5 3.2e-07 29.6 0.0 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ27564.1 - 2.3e-51 167.6 14.3 5.6e-06 25.8 0.0 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ27564.1 - 1.5e-50 168.6 17.6 2e-11 43.3 0.0 6.7 4 2 2 6 6 6 6 TPR repeat TPR_8 PF13181.1 OAJ27564.1 - 3.1e-34 114.1 12.1 0.00021 20.8 0.0 10.4 7 1 3 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ27564.1 - 8.5e-34 115.5 14.6 4e-08 33.7 0.1 7.5 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ27564.1 - 2.1e-31 105.4 13.3 0.00013 21.8 0.2 10.3 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ27564.1 - 3.6e-31 104.7 10.9 0.00089 19.6 0.0 10.3 2 2 7 10 10 10 7 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ27564.1 - 2.5e-29 98.7 4.5 0.011 15.4 0.0 9.7 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ27564.1 - 4.4e-28 97.0 15.8 1.3e-06 28.1 0.2 6.6 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ27564.1 - 1.6e-27 95.6 8.1 2e-07 31.2 0.3 7.1 3 3 2 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ27564.1 - 4.8e-23 79.9 10.0 0.0013 19.0 0.0 10.8 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ27564.1 - 1.9e-15 56.4 10.5 0.0041 16.9 0.1 6.9 1 1 8 9 9 9 7 Tetratricopeptide repeat Apc3 PF12895.2 OAJ27564.1 - 2.5e-13 49.9 6.0 1.5e-05 24.9 0.4 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 OAJ27564.1 - 1.8e-07 30.5 9.7 0.00091 18.3 0.7 4.4 1 1 2 4 4 4 3 Tetratricopeptide repeat TOM20_plant PF06552.7 OAJ27564.1 - 0.0028 17.2 0.1 3 7.3 0.0 3.2 2 1 1 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_20 PF14561.1 OAJ27564.1 - 0.018 15.1 0.0 0.018 15.1 0.0 4.5 5 1 0 5 5 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ27564.1 - 0.028 14.3 12.3 0.74 9.8 0.1 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.5 OAJ27564.1 - 0.039 12.7 1.0 5.2 5.7 0.1 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_WDAD PF04053.9 OAJ27564.1 - 0.3 9.8 1.1 7.6 5.1 0.1 2.2 2 0 0 2 2 2 0 Coatomer WD associated region RAB3GAP2_N PF14655.1 OAJ27564.1 - 3 6.7 3.8 5.4 5.9 2.6 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus UCH PF00443.24 OAJ27566.1 - 2.2e-70 236.8 0.0 3.9e-70 236.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ27566.1 - 1.1e-26 93.9 0.0 3.4e-26 92.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 OAJ27566.1 - 3.3e-07 30.2 0.8 8.3e-07 28.9 0.5 1.7 1 1 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.15 OAJ27566.1 - 7.9e-05 22.9 0.0 0.00097 19.4 0.0 2.6 2 0 0 2 2 2 1 Rhodanese-like domain MIT PF04212.13 OAJ27566.1 - 0.058 13.2 0.7 0.12 12.3 0.5 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DUF104 PF01954.11 OAJ27566.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF104 Paramyxo_PNT PF13825.1 OAJ27566.1 - 0.67 9.0 7.3 2 7.5 0.4 2.3 2 0 0 2 2 2 0 Paramyxovirus structural protein V/P N-terminus Bestrophin PF01062.16 OAJ27567.1 - 2.7e-38 131.6 1.5 9.6e-37 126.5 1.0 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Sec1 PF00995.18 OAJ27568.1 - 4.6e-78 263.2 0.0 5.7e-77 259.6 0.0 2.5 1 1 0 1 1 1 1 Sec1 family ATP_Ca_trans_C PF12424.3 OAJ27569.1 - 0.045 14.1 2.0 0.089 13.1 0.1 2.5 2 0 0 2 2 2 0 Plasma membrane calcium transporter ATPase C terminal LRR19-TM PF15176.1 OAJ27569.1 - 1 9.0 4.7 0.9 9.2 0.2 3.1 3 1 0 3 3 3 0 Leucine-rich repeat family 19 TM domain Transposase_21 PF02992.9 OAJ27571.1 - 7e-09 35.1 0.0 1.1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Nop14 PF04147.7 OAJ27571.1 - 0.046 11.6 8.5 0.066 11.1 5.9 1.1 1 0 0 1 1 1 0 Nop14-like family IncA PF04156.9 OAJ27573.1 - 0.45 10.0 7.6 0.85 9.1 5.3 1.4 1 0 0 1 1 1 0 IncA protein Vfa1 PF08432.5 OAJ27573.1 - 0.84 9.6 6.0 0.12 12.3 1.5 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RRN3 PF05327.6 OAJ27573.1 - 5.4 5.0 9.3 7.5 4.5 6.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AAA PF00004.24 OAJ27574.1 - 0.0018 18.4 0.0 0.0018 18.4 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF3435 PF11917.3 OAJ27575.1 - 0.00054 18.8 0.0 0.0007 18.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Lyase_aromatic PF00221.14 OAJ27576.1 - 2.4e-157 524.2 4.4 3e-157 523.8 3.1 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase G-patch PF01585.18 OAJ27577.1 - 6.2e-14 51.5 0.7 6.2e-14 51.5 0.5 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 OAJ27577.1 - 0.00012 21.8 0.3 0.00012 21.8 0.2 3.8 4 1 0 4 4 4 1 DExH-box splicing factor binding site Daxx PF03344.10 OAJ27577.1 - 0.033 12.6 24.2 0.049 12.1 16.8 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 OAJ27577.1 - 1.3 6.9 17.5 0.017 13.2 3.2 2.1 2 0 0 2 2 2 0 CDC45-like protein Sds3 PF08598.6 OAJ27578.1 - 0.012 15.1 0.3 0.019 14.4 0.2 1.2 1 0 0 1 1 1 0 Sds3-like TT_ORF2 PF02957.10 OAJ27578.1 - 0.15 12.7 3.1 0.15 12.7 0.1 2.2 1 1 1 2 2 2 0 TT viral ORF2 DUF4414 PF14377.1 OAJ27578.1 - 2 8.3 5.0 21 5.1 1.7 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4414) PH PF00169.24 OAJ27579.1 - 8.8e-08 32.2 0.0 2.4e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_7 PF15408.1 OAJ27579.1 - 0.066 13.1 0.0 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Cauli_VI PF01693.11 OAJ27580.1 - 0.0023 17.8 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin She9_MDM33 PF05546.6 OAJ27581.1 - 3.6e-60 203.0 9.1 5.3e-60 202.5 6.3 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family TINF2_N PF14973.1 OAJ27581.1 - 0.02 15.0 0.9 2 8.5 0.0 2.2 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus DUF2524 PF10732.4 OAJ27581.1 - 2 8.5 8.9 0.36 10.9 1.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) GDC-P PF02347.11 OAJ27582.1 - 1.2e-183 610.7 0.0 3e-171 569.8 0.0 2.8 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 OAJ27582.1 - 0.00021 20.5 0.0 0.00051 19.2 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase DUF1885 PF08968.5 OAJ27582.1 - 0.087 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) SGL PF08450.7 OAJ27583.1 - 0.065 12.5 0.1 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region TMP_2 PF06791.8 OAJ27584.1 - 0.0072 15.9 0.0 0.0098 15.5 0.0 1.3 1 1 0 1 1 1 1 Prophage tail length tape measure protein Sipho_Gp157 PF05565.6 OAJ27584.1 - 0.029 13.9 0.6 0.036 13.6 0.4 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 Uso1_p115_C PF04871.8 OAJ27584.1 - 0.038 13.9 0.5 0.049 13.5 0.3 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2857 PF11198.3 OAJ27584.1 - 0.062 12.8 0.2 0.075 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) HHA PF05321.6 OAJ27584.1 - 0.11 12.6 0.5 16 5.7 0.0 2.2 2 0 0 2 2 2 0 Haemolysin expression modulating protein Methyltrn_RNA_2 PF04013.7 OAJ27584.1 - 0.11 11.9 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase HsbA PF12296.3 OAJ27585.1 - 2.6e-16 59.6 13.0 4.1e-16 58.9 9.0 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A ALS_ss_C PF10369.4 OAJ27585.1 - 0.02 14.6 0.2 0.23 11.2 0.1 2.2 1 1 1 2 2 2 0 Small subunit of acetolactate synthase Baculo_PEP_C PF04513.7 OAJ27585.1 - 0.17 11.6 7.6 0.21 11.3 5.1 1.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUN14 PF04930.10 OAJ27585.1 - 0.54 10.5 3.6 1.1 9.5 0.9 2.3 1 1 0 2 2 2 0 FUN14 family Ribosomal_L22 PF00237.14 OAJ27585.1 - 0.84 9.6 3.3 2.4 8.1 2.3 2.0 1 1 0 1 1 1 0 Ribosomal protein L22p/L17e Iso_dh PF00180.15 OAJ27586.1 - 1.7e-101 339.6 0.0 2.2e-101 339.3 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PhzC-PhzF PF02567.11 OAJ27587.1 - 5.9e-40 137.2 0.0 7.1e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 OAJ27587.1 - 0.002 17.0 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 Proline racemase Fungal_trans PF04082.13 OAJ27588.1 - 2.9e-11 42.7 0.1 4.4e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ27588.1 - 0.0029 17.4 2.0 0.005 16.7 1.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.14 OAJ27588.1 - 0.25 11.7 6.1 0.8 10.1 4.2 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein F-box-like PF12937.2 OAJ27589.1 - 6.4e-09 35.3 1.8 1.6e-08 34.1 1.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ27589.1 - 3.5e-07 29.7 1.3 6e-07 28.9 0.9 1.4 1 0 0 1 1 1 1 F-box domain CD99L2 PF12301.3 OAJ27589.1 - 0.85 9.2 8.4 0.03 14.0 1.0 1.9 2 0 0 2 2 2 0 CD99 antigen like protein 2 CSTF_C PF14304.1 OAJ27591.1 - 0.046 12.9 1.4 0.1 11.9 0.9 1.5 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal Pox_A21 PF05323.7 OAJ27592.1 - 0.062 13.7 0.1 0.12 12.8 0.1 1.5 1 1 0 1 1 1 0 Poxvirus A21 Protein URO-D PF01208.12 OAJ27594.1 - 2.9e-130 434.1 0.0 3.3e-130 433.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Ribosomal_L11_N PF03946.9 OAJ27595.1 - 4.3e-18 64.5 0.1 7.1e-18 63.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 OAJ27595.1 - 3.7e-11 42.9 0.1 6.5e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Mg_trans_NIPA PF05653.9 OAJ27596.1 - 1e-107 359.5 15.1 1.4e-107 359.1 10.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 OAJ27596.1 - 2e-08 34.3 1.5 2e-08 34.3 1.0 3.0 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 OAJ27596.1 - 9.8e-05 22.3 6.6 9.8e-05 22.3 4.6 3.1 3 1 0 3 3 3 2 EamA-like transporter family WD40 PF00400.27 OAJ27597.1 - 5.7e-22 76.7 10.6 1.9e-06 27.4 0.0 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 OAJ27597.1 - 0.2 11.3 0.2 41 3.7 0.0 3.3 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A PI3_PI4_kinase PF00454.22 OAJ27598.1 - 8.7e-53 179.2 0.4 1.3e-52 178.6 0.3 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 OAJ27598.1 - 4.4e-43 147.6 0.0 6.1e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 FAT domain Rapamycin_bind PF08771.6 OAJ27598.1 - 9.2e-39 131.5 1.2 2.7e-38 130.0 0.8 1.9 1 0 0 1 1 1 1 Rapamycin binding domain FATC PF02260.15 OAJ27598.1 - 1.4e-10 40.4 0.0 3.3e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 FATC domain TPT PF03151.11 OAJ27599.1 - 7.9e-21 74.3 13.0 7.9e-21 74.3 9.0 2.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 OAJ27599.1 - 0.0055 16.7 7.5 0.0055 16.7 5.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family zf-met2 PF12907.2 OAJ27600.1 - 3.2e-13 49.4 0.9 4.7e-13 48.8 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 OAJ27600.1 - 3.9e-09 37.0 9.6 3.9e-09 37.0 6.6 1.8 2 0 0 2 2 2 1 4F5 protein family Eapp_C PF10238.4 OAJ27600.1 - 0.066 13.1 0.8 0.083 12.7 0.5 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein zinc_ribbon_4 PF13717.1 OAJ27600.1 - 0.072 12.7 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 OAJ27600.1 - 0.084 13.2 0.4 11 6.5 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zinc_ribbon_5 PF13719.1 OAJ27600.1 - 0.089 12.3 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain PI3_PI4_kinase PF00454.22 OAJ27601.1 - 2.2e-55 187.6 0.6 3.3e-55 187.1 0.4 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 OAJ27601.1 - 2.5e-43 148.3 0.0 3.6e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 FAT domain Rapamycin_bind PF08771.6 OAJ27601.1 - 1.9e-24 85.6 0.2 4.6e-24 84.4 0.2 1.7 1 0 0 1 1 1 1 Rapamycin binding domain FATC PF02260.15 OAJ27601.1 - 8.6e-10 37.8 0.1 1.8e-09 36.8 0.1 1.6 1 0 0 1 1 1 1 FATC domain TFIID-18kDa PF02269.11 OAJ27601.1 - 0.045 13.5 0.1 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit IMS PF00817.15 OAJ27602.1 - 9.6e-38 129.3 0.1 3.2e-37 127.5 0.1 1.9 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 OAJ27602.1 - 4.3e-06 26.6 0.0 9.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF1610 PF07754.6 OAJ27602.1 - 0.092 12.8 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) IMS_HHH PF11798.3 OAJ27602.1 - 0.16 12.0 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif Fungal_trans PF04082.13 OAJ27604.1 - 1.9e-09 36.7 0.0 4e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ27604.1 - 2.1e-07 30.7 8.2 3.8e-07 29.8 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 OAJ27604.1 - 0.057 13.6 9.0 0.11 12.6 6.2 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Peptidase_M16_C PF05193.16 OAJ27604.1 - 0.2 11.3 0.0 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase M16 inactive domain Sec20 PF03908.8 OAJ27605.1 - 3.9e-20 71.3 0.7 3.9e-20 71.3 0.5 1.9 2 0 0 2 2 2 1 Sec20 DNA_ligase_A_N PF04675.9 OAJ27606.1 - 2.9e-10 40.2 0.0 3.9e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 DNA ligase N terminus Fungal_trans PF04082.13 OAJ27607.1 - 7.5e-10 38.1 0.1 2e-09 36.7 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ27607.1 - 9e-08 31.9 6.2 1.5e-07 31.2 4.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4448 PF14610.1 OAJ27609.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) RNase_H PF00075.19 OAJ27612.1 - 1e-16 61.4 0.1 2.1e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAJ27612.1 - 1.6e-05 24.5 0.0 3.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like Exo_endo_phos_2 PF14529.1 OAJ27612.1 - 0.084 12.4 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase 2Fe-2S_thioredx PF01257.14 OAJ27614.1 - 3.6e-59 198.5 0.0 4.5e-59 198.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.6 OAJ27614.1 - 0.12 12.6 0.1 0.27 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1636) rve PF00665.21 OAJ27616.1 - 2.6e-08 34.0 0.0 5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ27617.1 - 4.1e-24 85.1 0.0 5.8e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MULE PF10551.4 OAJ27618.1 - 3.8e-12 46.1 0.1 1.4e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 OAJ27618.1 - 7.2e-09 34.6 2.5 3.4e-08 32.4 0.1 2.2 2 0 0 2 2 2 1 Transposase, Mutator family FAR1 PF03101.10 OAJ27618.1 - 0.014 15.9 1.2 0.029 14.8 0.8 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain NB-ARC PF00931.17 OAJ27619.1 - 5.4e-05 22.1 0.0 8.4e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 OAJ27619.1 - 0.0013 18.6 0.3 0.0054 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 OAJ27619.1 - 0.0053 15.5 0.0 0.0077 15.0 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 OAJ27619.1 - 0.012 16.4 0.1 0.046 14.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 OAJ27619.1 - 0.02 14.4 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 OAJ27619.1 - 0.026 13.4 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.13 OAJ27619.1 - 0.03 13.8 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.5 OAJ27619.1 - 0.09 11.9 0.0 0.2 10.8 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 OAJ27619.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 OAJ27619.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.24 OAJ27619.1 - 0.16 12.1 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) COesterase PF00135.23 OAJ27620.1 - 6.1e-77 259.5 0.3 2.2e-68 231.2 0.3 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ27620.1 - 0.00083 18.9 0.1 0.0062 16.1 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold KH_1 PF00013.24 OAJ27621.1 - 2.4e-05 23.8 0.0 4.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 OAJ27621.1 - 4.7e-05 22.9 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 OAJ27621.1 - 0.047 13.3 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 KH domain RhoGEF PF00621.15 OAJ27623.1 - 1.4e-38 132.5 0.0 2.1e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.2 OAJ27623.1 - 3.7e-12 45.5 0.5 1.9e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ27623.1 - 4.2e-10 39.2 0.5 1.8e-05 24.4 0.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 OAJ27623.1 - 7.6e-08 31.3 0.3 0.14 12.2 0.0 4.8 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 OAJ27623.1 - 1.3e-05 24.6 0.9 0.47 10.8 0.0 4.3 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 OAJ27623.1 - 0.012 15.5 1.9 5.1 7.4 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat SSV1_ORF_D-335 PF07935.6 OAJ27623.1 - 0.66 9.7 0.3 13 5.6 0.0 2.4 2 0 0 2 2 2 0 ORF D-335-like protein HSF_DNA-bind PF00447.12 OAJ27624.1 - 4.8e-31 107.0 0.2 7.1e-31 106.4 0.2 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Nucleoplasmin PF03066.10 OAJ27624.1 - 0.039 13.4 2.8 0.067 12.7 1.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 OAJ27624.1 - 0.95 7.8 9.9 3.9 5.8 0.1 2.2 2 0 0 2 2 2 0 Daxx Family PBP1_TM PF14812.1 OAJ27624.1 - 4.2 7.7 7.2 13 6.2 5.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 OAJ27624.1 - 4.6 7.5 10.1 10 6.4 7.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 OAJ27624.1 - 8.5 5.9 7.6 11 5.5 4.1 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Alpha-amylase_C PF02806.13 OAJ27625.1 - 1.2e-26 92.6 0.2 3.5e-26 91.1 0.1 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 OAJ27625.1 - 2.3e-19 69.9 0.0 4.2e-15 55.9 0.0 2.6 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 OAJ27625.1 - 4.2e-14 52.3 0.4 1.2e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) AP_endonuc_2 PF01261.19 OAJ27625.1 - 0.0075 15.5 0.0 0.021 14.0 0.0 1.8 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_hydro_66 PF13199.1 OAJ27625.1 - 0.023 13.1 0.1 0.042 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 hDGE_amylase PF14701.1 OAJ27625.1 - 0.034 13.0 0.0 0.9 8.3 0.0 2.1 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme Aminotran_1_2 PF00155.16 OAJ27625.1 - 0.12 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II PAT1 PF09770.4 OAJ27626.1 - 0.042 12.1 68.6 0.054 11.7 47.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 OAJ27626.1 - 0.52 9.6 22.5 0.82 9.0 15.6 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MARVEL PF01284.18 OAJ27627.1 - 0.1 12.4 16.5 0.42 10.4 11.1 2.2 1 1 0 1 1 1 0 Membrane-associating domain MFS_1 PF07690.11 OAJ27628.1 - 8.5e-46 156.2 46.7 8.5e-46 156.2 32.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Septin PF00735.13 OAJ27629.1 - 2.7e-123 410.4 0.1 2.7e-123 410.4 0.1 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 OAJ27629.1 - 4.5e-07 29.8 0.0 1.3e-06 28.3 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 OAJ27629.1 - 2.3e-06 26.8 0.0 5.8e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 OAJ27629.1 - 3.3e-05 23.3 0.5 0.00051 19.5 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.17 OAJ27629.1 - 0.0003 20.2 0.3 0.0032 16.8 0.0 2.4 2 0 0 2 2 2 1 Ras family AAA_10 PF12846.2 OAJ27629.1 - 0.00047 19.6 0.0 0.00077 18.9 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 OAJ27629.1 - 0.0015 18.6 0.0 0.015 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.11 OAJ27629.1 - 0.0018 17.3 1.4 0.0039 16.3 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 OAJ27629.1 - 0.0033 17.9 0.2 0.021 15.3 0.0 2.4 2 1 0 2 2 2 1 Miro-like protein Arch_ATPase PF01637.13 OAJ27629.1 - 0.0033 17.1 1.7 1.5 8.4 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase Dynamin_N PF00350.18 OAJ27629.1 - 0.0041 16.9 6.2 0.063 13.0 0.0 3.3 2 2 0 3 3 3 1 Dynamin family AAA_16 PF13191.1 OAJ27629.1 - 0.0042 17.0 0.3 0.022 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 OAJ27629.1 - 0.0047 17.2 7.5 0.94 9.7 5.2 2.6 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 OAJ27629.1 - 0.008 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 OAJ27629.1 - 0.03 14.4 0.1 0.36 11.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 OAJ27629.1 - 0.03 14.0 0.1 0.1 12.2 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 OAJ27629.1 - 0.033 13.7 0.0 0.082 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAJ27629.1 - 0.061 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 OAJ27629.1 - 0.11 11.9 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Exonuc_VII_L PF02601.10 OAJ27629.1 - 0.19 10.8 7.2 0.4 9.8 5.0 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_5 PF07728.9 OAJ27629.1 - 0.21 11.3 1.5 1.5 8.5 0.0 2.8 3 1 1 4 4 3 0 AAA domain (dynein-related subfamily) YlqD PF11068.3 OAJ27629.1 - 0.38 10.7 8.7 1.1 9.3 6.0 1.8 1 0 0 1 1 1 0 YlqD protein DUF87 PF01935.12 OAJ27629.1 - 0.43 10.3 5.4 2 8.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 ArgK PF03308.11 OAJ27629.1 - 1 8.1 3.0 10 4.7 0.0 2.3 2 0 0 2 2 2 0 ArgK protein ATP_bind_1 PF03029.12 OAJ27629.1 - 1.5 8.2 4.5 19 4.6 0.0 3.2 4 1 0 4 4 4 0 Conserved hypothetical ATP binding protein IncA PF04156.9 OAJ27629.1 - 2 8.0 8.2 3.6 7.1 5.7 1.4 1 0 0 1 1 1 0 IncA protein Strep_SA_rep PF06696.6 OAJ27629.1 - 4 7.3 5.8 4.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Dimer_Tnp_hAT PF05699.9 OAJ27630.1 - 2.3e-08 33.5 0.0 7.2e-08 31.9 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAJ27630.1 - 0.023 14.6 0.0 0.059 13.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Vps26 PF03643.10 OAJ27631.1 - 5e-130 432.2 3.6 5.8e-130 432.0 2.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 OAJ27631.1 - 0.022 14.5 1.2 2 8.2 0.1 3.4 3 1 0 4 4 4 0 Arrestin (or S-antigen), N-terminal domain DUF4098 PF13345.1 OAJ27633.1 - 5.5e-10 39.0 7.9 1.5e-07 31.2 0.1 4.9 4 2 2 6 6 6 4 Domain of unknown function (DUF4098) Aminotran_5 PF00266.14 OAJ27634.1 - 1.7e-29 102.7 0.0 2.4e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 OAJ27634.1 - 0.00041 20.1 0.0 0.0014 18.5 0.0 1.9 2 1 0 2 2 2 1 B12 binding domain Beta_elim_lyase PF01212.16 OAJ27634.1 - 0.01 15.0 0.0 0.07 12.2 0.0 1.9 1 1 0 1 1 1 0 Beta-eliminating lyase UPF0180 PF03698.8 OAJ27634.1 - 0.1 12.4 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) Tropomyosin_1 PF12718.2 OAJ27635.1 - 3.5e-44 150.1 30.5 4.2e-44 149.8 21.1 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 OAJ27635.1 - 1.6e-12 47.0 30.8 6.9e-07 28.5 7.4 2.1 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.4 OAJ27635.1 - 0.0002 21.2 31.7 0.0019 18.0 6.0 3.2 1 1 2 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.14 OAJ27635.1 - 0.0005 19.6 33.1 0.0097 15.4 12.1 2.0 1 1 1 2 2 2 2 Ezrin/radixin/moesin family TelA PF05816.6 OAJ27635.1 - 0.0009 18.0 3.0 0.0009 18.0 2.1 2.0 1 1 1 2 2 2 1 Toxic anion resistance protein (TelA) BLOC1_2 PF10046.4 OAJ27635.1 - 0.0027 17.7 14.9 0.013 15.6 1.2 3.2 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 RasGAP_C PF03836.10 OAJ27635.1 - 0.0071 16.0 12.0 0.0099 15.5 8.3 1.3 1 0 0 1 1 1 1 RasGAP C-terminus FliD_C PF07195.7 OAJ27635.1 - 0.021 14.1 12.4 0.1 11.8 3.0 2.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus TPR_MLP1_2 PF07926.7 OAJ27635.1 - 0.023 14.4 29.4 0.42 10.3 13.2 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 OAJ27635.1 - 0.027 14.3 26.8 0.48 10.3 5.0 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Myosin_tail_1 PF01576.14 OAJ27635.1 - 0.038 11.7 30.3 0.046 11.4 21.0 1.1 1 0 0 1 1 1 0 Myosin tail Dynamitin PF04912.9 OAJ27635.1 - 0.045 12.5 14.5 0.08 11.7 10.1 1.6 1 1 0 1 1 1 0 Dynamitin DUF4200 PF13863.1 OAJ27635.1 - 0.06 13.2 29.0 0.18 11.7 5.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Filament PF00038.16 OAJ27635.1 - 0.071 12.5 26.0 0.25 10.7 8.3 2.0 1 1 1 2 2 2 0 Intermediate filament protein EzrA PF06160.7 OAJ27635.1 - 0.12 10.5 19.3 0.034 12.3 4.2 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA V_ATPase_I PF01496.14 OAJ27635.1 - 0.13 10.0 14.5 0.16 9.8 10.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF919 PF06034.6 OAJ27635.1 - 0.16 11.5 7.4 0.13 11.8 0.4 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) HrpB7 PF09486.5 OAJ27635.1 - 0.18 11.7 18.0 0.28 11.0 4.3 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF641 PF04859.7 OAJ27635.1 - 0.24 11.1 17.8 0.075 12.7 3.2 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) APG6 PF04111.7 OAJ27635.1 - 0.26 10.2 29.7 1 8.3 9.4 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF3584 PF12128.3 OAJ27635.1 - 0.27 8.5 25.6 0.35 8.1 17.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF972 PF06156.8 OAJ27635.1 - 0.27 11.5 21.0 0.88 9.9 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HisKA_3 PF07730.8 OAJ27635.1 - 0.3 11.4 12.4 4.6 7.6 2.9 3.9 1 1 2 3 3 3 0 Histidine kinase Fib_alpha PF08702.5 OAJ27635.1 - 0.31 11.1 12.4 2 8.5 2.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.3 OAJ27635.1 - 0.34 10.1 20.0 1.4 8.0 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) LRS4 PF10422.4 OAJ27635.1 - 0.43 9.9 16.4 0.54 9.5 11.3 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 TMF_DNA_bd PF12329.3 OAJ27635.1 - 0.46 10.3 34.0 0.59 9.9 8.2 3.6 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Mod_r PF07200.8 OAJ27635.1 - 0.46 10.3 22.0 0.29 11.0 6.6 2.6 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.1 OAJ27635.1 - 0.5 9.5 25.7 1.3 8.1 13.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.15 OAJ27635.1 - 0.52 10.1 27.0 2.4 7.9 2.2 3.8 1 1 1 3 3 3 0 Prefoldin subunit AAA_13 PF13166.1 OAJ27635.1 - 0.65 8.3 19.7 2 6.7 12.9 1.7 1 1 0 1 1 1 0 AAA domain Striatin PF08232.7 OAJ27635.1 - 0.89 9.8 22.1 0.22 11.8 9.1 2.1 1 1 1 2 2 2 0 Striatin family CDC37_N PF03234.9 OAJ27635.1 - 0.94 9.7 18.6 1.3 9.3 12.9 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF1664 PF07889.7 OAJ27635.1 - 1.1 9.1 10.8 6 6.6 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.1 OAJ27635.1 - 1.1 8.1 18.8 1.8 7.4 13.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Laminin_II PF06009.7 OAJ27635.1 - 1.3 8.7 15.2 2.4 7.9 3.1 2.6 1 1 1 2 2 2 0 Laminin Domain II IpaD PF06511.6 OAJ27635.1 - 1.3 7.9 7.2 2 7.3 5.0 1.3 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD Spc7 PF08317.6 OAJ27635.1 - 1.4 7.5 24.3 1 7.9 6.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Occludin_ELL PF07303.8 OAJ27635.1 - 1.5 9.5 17.0 12 6.6 3.9 3.6 1 1 2 3 3 3 0 Occludin homology domain Sec20 PF03908.8 OAJ27635.1 - 1.5 8.5 5.5 0.54 10.0 1.3 2.1 2 0 0 2 2 2 0 Sec20 Flagellin_N PF00669.15 OAJ27635.1 - 1.6 8.5 6.8 0.6 9.8 0.7 2.4 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region Fmp27_WPPW PF10359.4 OAJ27635.1 - 1.7 6.9 22.6 2.7 6.3 7.1 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Reo_sigmaC PF04582.7 OAJ27635.1 - 1.8 7.6 5.8 6.6 5.8 1.7 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein SlyX PF04102.7 OAJ27635.1 - 1.9 8.8 14.0 1 9.7 2.0 3.2 1 1 2 3 3 2 0 SlyX CCDC155 PF14662.1 OAJ27635.1 - 2 7.9 29.5 0.66 9.5 6.2 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF812 PF05667.6 OAJ27635.1 - 2.1 6.7 24.9 0.94 7.9 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF2959 PF11172.3 OAJ27635.1 - 2.1 8.0 13.3 0.75 9.5 0.8 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2959) IncA PF04156.9 OAJ27635.1 - 2.3 7.7 28.3 95 2.5 19.5 2.1 1 1 0 1 1 1 0 IncA protein Cortex-I_coil PF09304.5 OAJ27635.1 - 2.4 8.2 25.2 0.4 10.7 6.4 2.7 2 1 0 2 2 2 0 Cortexillin I, coiled coil Laminin_I PF06008.9 OAJ27635.1 - 2.4 7.3 23.1 1.8 7.8 11.4 2.4 1 1 1 2 2 2 0 Laminin Domain I Ax_dynein_light PF10211.4 OAJ27635.1 - 2.6 7.8 22.5 0.74 9.6 6.0 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain Allexi_40kDa PF05549.6 OAJ27635.1 - 2.7 7.2 13.0 3.4 6.8 4.5 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF730 PF05325.6 OAJ27635.1 - 2.7 7.8 11.6 1.9 8.2 2.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF730) THOC7 PF05615.8 OAJ27635.1 - 3 8.1 23.3 0.29 11.4 5.9 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 Kinetocho_Slk19 PF12709.2 OAJ27635.1 - 3.5 7.7 20.8 4.4 7.4 1.6 3.1 1 1 1 3 3 2 0 Central kinetochore-associated DUF4140 PF13600.1 OAJ27635.1 - 3.8 8.0 23.8 5.4 7.5 2.7 3.6 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) CASP_C PF08172.7 OAJ27635.1 - 4.3 6.2 19.5 0.37 9.7 1.0 2.2 1 1 1 2 2 2 0 CASP C terminal Atg14 PF10186.4 OAJ27635.1 - 4.5 6.1 23.6 0.15 10.9 4.4 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Sipho_Gp157 PF05565.6 OAJ27635.1 - 5 6.6 16.8 2 7.9 4.7 2.3 1 1 1 2 2 2 0 Siphovirus Gp157 CorA PF01544.13 OAJ27635.1 - 5.4 5.9 6.3 7.6 5.4 4.1 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein KxDL PF10241.4 OAJ27635.1 - 5.6 6.9 7.7 1.2 9.1 1.3 2.6 1 1 2 3 3 3 0 Uncharacterized conserved protein Cep57_CLD PF14073.1 OAJ27635.1 - 5.6 6.7 24.2 0.97 9.2 8.6 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 ATG16 PF08614.6 OAJ27635.1 - 5.9 6.6 24.8 0.35 10.6 5.6 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Prefoldin PF02996.12 OAJ27635.1 - 6.8 6.3 22.8 44 3.7 0.4 3.9 1 1 0 2 2 2 0 Prefoldin subunit DUF724 PF05266.9 OAJ27635.1 - 7.1 6.2 24.4 5.8 6.4 6.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Syntaxin-6_N PF09177.6 OAJ27635.1 - 8.5 6.8 18.9 1 9.8 5.8 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FemAB PF02388.11 OAJ27635.1 - 8.7 4.8 15.8 1.3 7.6 2.3 2.1 1 1 0 2 2 2 0 FemAB family OmpH PF03938.9 OAJ27635.1 - 9.4 6.1 22.4 5.9e+02 0.3 15.4 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Tup_N PF08581.5 OAJ27635.1 - 9.6 6.4 14.7 0.68 10.1 1.8 2.7 2 1 0 2 2 2 0 Tup N-terminal HEAT_2 PF13646.1 OAJ27636.1 - 0.0051 17.0 1.6 0.0051 17.0 1.1 2.3 1 1 1 2 2 2 2 HEAT repeats DUF4098 PF13345.1 OAJ27638.1 - 2.3e-05 24.2 0.2 0.0017 18.2 0.0 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4098) PBP1_TM PF14812.1 OAJ27638.1 - 0.52 10.6 13.0 15 5.9 0.5 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDE_3 PF13358.1 OAJ27639.1 - 1.3e-14 54.2 0.0 1.8e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 OAJ27639.1 - 0.0026 17.8 0.0 0.0039 17.2 0.0 1.4 1 1 0 1 1 1 1 Integrase core domain DUF423 PF04241.10 OAJ27640.1 - 1.8e-24 85.4 3.3 1.8e-24 85.4 2.3 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF423) Bax1-I PF01027.15 OAJ27640.1 - 0.12 12.0 3.8 0.14 11.6 2.6 1.3 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Glyco_transf_28 PF03033.15 OAJ27641.1 - 8.3e-28 96.8 0.1 2.6e-27 95.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 OAJ27641.1 - 3.5e-08 32.8 0.3 0.00093 18.6 0.0 3.2 3 0 0 3 3 3 2 GRAM domain UDPGT PF00201.13 OAJ27641.1 - 0.00016 20.4 0.0 0.00028 19.5 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.24 OAJ27641.1 - 0.094 12.9 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 PH domain Glyco_tran_28_C PF04101.11 OAJ27641.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Antimicrobial10 PF08105.6 OAJ27642.1 - 0.16 11.6 0.4 0.42 10.2 0.3 1.7 1 0 0 1 1 1 0 Metchnikowin family Histone PF00125.19 OAJ27644.1 - 2.6e-09 37.0 0.1 3.1e-09 36.8 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ27644.1 - 0.00047 20.2 0.1 0.00072 19.6 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 OAJ27644.1 - 0.0007 19.4 0.0 0.00095 19.0 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) PCP_red PF08369.5 OAJ27644.1 - 0.0087 15.9 0.9 1.7 8.5 0.1 2.8 2 1 0 2 2 2 1 Proto-chlorophyllide reductase 57 kD subunit CENP-T PF15511.1 OAJ27644.1 - 0.013 14.8 0.0 0.013 14.7 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 OAJ27644.1 - 0.063 13.0 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated DUF4095 PF13338.1 OAJ27644.1 - 0.068 13.3 0.1 0.08 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4095) CBFD_NFYB_HMF PF00808.18 OAJ27644.1 - 0.1 12.6 0.1 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_S49 PF01343.13 OAJ27646.1 - 0.057 13.1 0.1 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 DEC-1_N PF04625.8 OAJ27647.1 - 4.1 5.9 11.6 4 6.0 8.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Apolipoprotein PF01442.13 OAJ27648.1 - 2.1e-06 27.4 7.6 2.6e-06 27.1 5.3 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Prominin PF05478.6 OAJ27648.1 - 0.0027 15.3 1.0 0.0033 15.0 0.7 1.3 1 0 0 1 1 1 1 Prominin DUF1664 PF07889.7 OAJ27648.1 - 0.023 14.4 3.8 0.64 9.8 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Histidinol_dh PF00815.15 OAJ27648.1 - 0.041 12.5 0.2 0.051 12.2 0.1 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase Baculo_PEP_C PF04513.7 OAJ27648.1 - 0.076 12.8 6.1 0.61 9.9 3.7 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2317 PF10079.4 OAJ27648.1 - 0.079 11.5 3.0 0.11 11.1 2.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) CENP-F_leu_zip PF10473.4 OAJ27648.1 - 0.11 12.3 6.7 0.59 9.9 1.2 3.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fzo_mitofusin PF04799.8 OAJ27648.1 - 0.12 11.7 8.3 0.54 9.6 5.0 2.1 1 1 1 2 2 2 0 fzo-like conserved region Muted PF14942.1 OAJ27648.1 - 0.22 11.4 6.8 0.74 9.6 2.2 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF842 PF05811.8 OAJ27648.1 - 0.22 10.9 4.0 0.32 10.4 2.6 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) ApoLp-III PF07464.6 OAJ27648.1 - 0.25 11.3 5.0 1.2 9.1 3.2 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.8 OAJ27648.1 - 1.7 9.1 6.6 2.9 8.3 2.9 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) MxiH PF09392.5 OAJ27648.1 - 2.6 8.6 6.7 1.5 9.4 2.7 2.2 2 1 0 2 2 2 0 Type III secretion needle MxiH like Homeobox_KN PF05920.6 OAJ27650.1 - 2.3e-09 36.7 0.0 6.8e-09 35.2 0.0 1.9 1 1 0 1 1 1 1 Homeobox KN domain Ribonucleas_3_3 PF14622.1 OAJ27651.1 - 2.2e-20 72.9 0.0 4.3e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Brevenin PF03032.10 OAJ27651.1 - 0.25 11.2 0.4 0.55 10.1 0.0 1.7 2 0 0 2 2 2 0 Brevenin/esculentin/gaegurin/rugosin family Ndc1_Nup PF09531.5 OAJ27651.1 - 0.56 8.5 4.7 0.7 8.2 3.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.4 OAJ27651.1 - 2 6.5 22.9 2.6 6.1 15.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GKAP PF03359.8 OAJ27651.1 - 2.2 7.7 9.7 2.8 7.4 6.8 1.1 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein TFIIA PF03153.8 OAJ27651.1 - 4.4 7.1 10.9 5.8 6.7 7.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 OAJ27651.1 - 8.6 5.6 17.3 11 5.2 12.0 1.2 1 0 0 1 1 1 0 Vta1 like DAO PF01266.19 OAJ27652.1 - 8.1e-42 143.3 0.6 1e-40 139.7 0.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ27652.1 - 0.0003 20.7 0.1 0.0012 18.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAJ27652.1 - 0.041 14.2 0.0 0.97 9.8 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ27652.1 - 0.068 13.0 0.0 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ATP13 PF12921.2 OAJ27652.1 - 0.1 11.9 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ATPase expression Shikimate_DH PF01488.15 OAJ27652.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 OAJ27652.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Mqo PF06039.10 OAJ27652.1 - 0.21 9.6 0.0 0.31 9.1 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) FHA PF00498.21 OAJ27653.1 - 8.8e-15 54.5 0.0 1.9e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain Catalase PF00199.14 OAJ27654.1 - 1.4e-160 534.1 1.3 1.8e-160 533.8 0.9 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 OAJ27654.1 - 3e-15 55.8 0.1 8.9e-15 54.3 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive ATP13 PF12921.2 OAJ27655.1 - 0.067 12.5 0.0 0.35 10.2 0.0 2.1 1 1 1 2 2 2 0 Mitochondrial ATPase expression Ribosomal_L44 PF00935.14 OAJ27657.1 - 2.1e-35 120.5 12.3 3.1e-35 120.0 8.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L14e PF01929.12 OAJ27658.1 - 8.9e-25 86.8 0.7 1.4e-24 86.2 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 OAJ27658.1 - 0.026 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 KOW motif DUF1768 PF08719.6 OAJ27664.1 - 5.5e-25 87.9 0.0 7.6e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Pkinase PF00069.20 OAJ27665.1 - 1.2e-53 181.8 0.0 1.9e-53 181.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ27665.1 - 3.5e-42 144.2 0.0 4.9e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ27665.1 - 0.014 14.3 0.0 0.033 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 OAJ27665.1 - 0.026 14.2 1.4 0.087 12.5 0.5 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 OAJ27665.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA PF03153.8 OAJ27665.1 - 4.1 7.1 9.5 6.3 6.5 6.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Menin PF05053.8 OAJ27665.1 - 5.9 4.9 7.5 8.4 4.4 5.2 1.3 1 0 0 1 1 1 0 Menin Med21 PF11221.3 OAJ27667.1 - 7.2e-17 61.6 1.6 1e-16 61.2 1.1 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex IncA PF04156.9 OAJ27667.1 - 0.18 11.3 3.7 0.24 10.9 2.6 1.1 1 0 0 1 1 1 0 IncA protein DHH PF01368.15 OAJ27668.1 - 4.4e-08 32.8 0.3 2.8e-07 30.2 0.0 2.4 2 2 0 2 2 2 1 DHH family DHHA2 PF02833.9 OAJ27668.1 - 9.1e-05 22.6 0.0 0.0002 21.5 0.0 1.5 1 0 0 1 1 1 1 DHHA2 domain Sugar_tr PF00083.19 OAJ27669.1 - 5.6e-86 288.8 25.3 6.8e-86 288.6 17.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ27669.1 - 6.8e-14 51.3 41.4 5e-12 45.2 10.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Met_asp_mut_E PF06368.6 OAJ27672.1 - 0.17 10.0 0.0 0.24 9.5 0.0 1.1 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Helicase_C_3 PF13625.1 OAJ27674.1 - 1.9e-25 89.1 0.0 4.7e-25 87.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ27674.1 - 3.4e-14 53.1 0.0 6.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 OAJ27674.1 - 2.3e-11 43.0 0.0 3.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ27674.1 - 9e-10 38.2 0.1 2.3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cyclin_N PF00134.18 OAJ27675.1 - 1.5e-11 43.9 0.4 1.5e-11 43.9 0.3 2.3 3 0 0 3 3 3 1 Cyclin, N-terminal domain TFIIB PF00382.14 OAJ27675.1 - 0.00022 20.9 0.5 0.00055 19.6 0.4 1.7 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Helicase_C PF00271.26 OAJ27676.1 - 6.3e-12 45.1 0.0 2e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ27676.1 - 4.7e-11 42.4 0.0 5.6e-10 38.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ27676.1 - 0.0015 18.3 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Med3 PF11593.3 OAJ27676.1 - 8 5.5 11.5 0.24 10.6 2.3 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal PIF1 PF05970.9 OAJ27678.1 - 1.1e-47 162.7 0.0 1.8e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ27678.1 - 7.8e-16 58.3 0.1 1.8e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 OAJ27678.1 - 1.9e-08 34.1 0.1 3.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAJ27678.1 - 0.0012 18.5 0.0 0.0037 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 OAJ27678.1 - 0.0013 18.9 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ27678.1 - 0.0015 18.6 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 OAJ27678.1 - 0.0018 18.0 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 OAJ27678.1 - 0.0035 17.0 0.0 0.0065 16.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 OAJ27678.1 - 0.025 14.5 0.0 11 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.4 OAJ27678.1 - 0.035 13.0 0.0 0.12 11.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 OAJ27678.1 - 0.047 12.5 0.0 0.092 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 OAJ27678.1 - 0.074 12.8 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain SCP2 PF02036.12 OAJ27679.1 - 4.6e-16 58.9 0.0 7.6e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family WD40 PF00400.27 OAJ27680.1 - 8.4e-08 31.8 14.6 0.0058 16.4 2.6 5.6 5 1 0 5 5 5 2 WD domain, G-beta repeat Equine_IAV_S2 PF06502.6 OAJ27680.1 - 0.067 13.0 0.2 0.38 10.6 0.0 2.3 2 0 0 2 2 2 0 Equine infectious anaemia virus S2 protein D123 PF07065.9 OAJ27681.1 - 1.8e-62 211.1 0.0 5.5e-62 209.5 0.0 1.8 1 1 0 1 1 1 1 D123 Pkinase PF00069.20 OAJ27682.1 - 1.1e-60 204.9 0.0 9.9e-59 198.5 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ27682.1 - 2e-22 79.5 0.0 1.7e-20 73.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ27682.1 - 1.2e-05 24.3 0.0 2.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ27682.1 - 0.0065 16.2 0.1 0.038 13.7 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAJ27682.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase CDK2AP PF09806.4 OAJ27682.1 - 0.028 14.6 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3138 PF11336.3 OAJ27682.1 - 0.034 12.3 3.4 0.046 11.8 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1679 PF07914.6 OAJ27682.1 - 0.067 11.8 0.5 0.15 10.6 0.3 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) Aminotran_1_2 PF00155.16 OAJ27683.1 - 3.2e-58 197.4 0.0 4.2e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Ofd1_CTDD PF10637.4 OAJ27684.1 - 3.1e-88 295.3 0.0 3e-82 275.7 0.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 OAJ27684.1 - 1.5e-17 63.9 0.1 3.3e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nop14 PF04147.7 OAJ27684.1 - 1.2 6.9 13.0 1.9 6.3 9.0 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 OAJ27684.1 - 1.4 7.9 13.6 3 6.8 9.4 1.5 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.7 OAJ27684.1 - 2.5 7.7 8.6 5.9 6.5 6.0 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein rve PF00665.21 OAJ27686.1 - 6.1e-23 81.1 0.0 1.2e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain UBN2_2 PF14227.1 OAJ27686.1 - 2e-12 46.7 0.0 3.3e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ27686.1 - 3.5e-09 36.4 0.0 5.8e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 OAJ27686.1 - 0.0089 15.4 0.1 0.025 13.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) gag_pre-integrs PF13976.1 OAJ27686.1 - 0.01 15.4 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain RVP PF00077.15 OAJ27686.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease UBN2_3 PF14244.1 OAJ27686.1 - 0.063 12.8 0.2 0.93 9.0 0.1 2.3 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type CCDC-167 PF15188.1 OAJ27687.1 - 0.48 10.4 2.2 0.92 9.4 1.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF2146 PF10220.4 OAJ27687.1 - 5.4 4.8 7.7 6.9 4.5 5.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) RVT_2 PF07727.9 OAJ27688.1 - 6.6e-16 58.0 0.0 8.5e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Autotransporter PF03797.14 OAJ27688.1 - 0.038 13.3 0.1 0.061 12.6 0.1 1.2 1 0 0 1 1 1 0 Autotransporter beta-domain RVT_3 PF13456.1 OAJ27688.1 - 0.052 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like dCMP_cyt_deam_1 PF00383.17 OAJ27690.1 - 1.4e-24 85.6 0.8 2.5e-24 84.8 0.6 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 OAJ27690.1 - 0.00037 21.3 0.0 0.00095 19.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ27690.1 - 0.0018 18.1 0.0 0.0044 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ27690.1 - 0.0029 17.9 0.0 0.0082 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain TRAM_LAG1_CLN8 PF03798.11 OAJ27693.1 - 1.3e-31 109.7 24.2 1.3e-31 109.7 16.8 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 OAJ27693.1 - 1.5e-12 46.8 0.0 4.5e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein tRNA-synt_2b PF00587.20 OAJ27694.1 - 2.7e-65 219.1 0.0 3.9e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ27694.1 - 3.6e-21 74.8 0.3 1.4e-20 72.9 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain LtrA PF06772.6 OAJ27695.1 - 1.8e-17 63.3 12.2 2.5e-17 62.8 8.5 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) 4HBT_2 PF13279.1 OAJ27696.1 - 6.5e-18 65.3 0.1 1.1e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 OAJ27696.1 - 0.00022 20.2 0.0 0.001 18.0 0.1 1.9 2 0 0 2 2 2 1 Acyl-ACP thioesterase 4HBT PF03061.17 OAJ27696.1 - 0.0079 16.3 0.0 0.016 15.3 0.0 1.6 1 1 0 1 1 1 1 Thioesterase superfamily adh_short PF00106.20 OAJ27697.1 - 4.3e-20 72.3 0.0 6.4e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ27697.1 - 3.6e-06 26.9 0.0 5.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ27697.1 - 8.1e-06 25.6 0.1 2.5e-05 24.0 0.1 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAJ27697.1 - 0.00063 19.2 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family WD40 PF00400.27 OAJ27698.1 - 2.6e-24 84.1 7.6 2e-10 40.1 0.5 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 OAJ27698.1 - 1.1e-17 63.6 0.0 2.8e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex GARS_A PF01071.14 OAJ27699.1 - 2.8e-67 226.0 0.0 4.1e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 OAJ27699.1 - 1.7e-31 108.6 0.0 5.3e-31 107.0 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 OAJ27699.1 - 1.2e-26 92.7 0.1 2.8e-26 91.5 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS_C PF02769.17 OAJ27699.1 - 2.4e-25 89.3 0.0 5e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 OAJ27699.1 - 7.7e-17 61.3 2.1 1.7e-16 60.1 0.7 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Shikimate_DH PF01488.15 OAJ27699.1 - 0.039 14.0 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase WD40 PF00400.27 OAJ27700.1 - 2.5e-51 169.8 23.4 1.1e-08 34.5 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Sfi1 PF08457.5 OAJ27700.1 - 0.17 10.2 0.3 0.21 9.9 0.2 1.1 1 0 0 1 1 1 0 Sfi1 spindle body protein zf-C2H2 PF00096.21 OAJ27701.1 - 4.6e-25 86.4 56.9 0.0014 18.8 0.4 10.6 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ27701.1 - 1.3e-21 75.2 56.4 0.0035 17.5 0.7 10.6 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ27701.1 - 1.1e-06 28.5 4.9 0.00097 19.3 1.5 12.7 14 1 0 14 14 14 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 OAJ27701.1 - 4.6e-06 26.6 17.2 2.7 8.2 0.0 7.6 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding Ank_2 PF12796.2 OAJ27702.1 - 1.5e-11 44.5 0.0 1.5e-10 41.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ27702.1 - 4.9e-10 38.7 1.1 0.023 14.4 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 OAJ27702.1 - 2e-07 31.3 0.2 0.0085 16.5 0.0 4.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ27702.1 - 7.6e-07 29.1 0.5 0.085 13.1 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ27702.1 - 0.00012 21.9 0.0 17 6.0 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat RVP PF00077.15 OAJ27702.1 - 0.19 11.6 0.0 22 5.0 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease OB_NTP_bind PF07717.11 OAJ27704.1 - 2e-17 63.0 0.0 6.9e-17 61.3 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 OAJ27704.1 - 6.2e-13 48.6 1.3 9.3e-13 48.0 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ27704.1 - 7.1e-09 35.4 0.0 1.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ27704.1 - 0.00026 20.5 0.2 0.19 11.2 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase T2SE PF00437.15 OAJ27704.1 - 0.00071 18.5 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 OAJ27704.1 - 0.0015 18.0 0.0 0.037 13.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 OAJ27704.1 - 0.0038 17.3 0.1 0.44 10.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain ResIII PF04851.10 OAJ27704.1 - 0.01 15.6 0.0 1.6 8.5 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 OAJ27704.1 - 0.047 13.2 0.4 0.34 10.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain PhoH PF02562.11 OAJ27704.1 - 0.15 11.2 0.2 0.73 9.0 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein DUF1741 PF08427.5 OAJ27705.1 - 5e-11 42.5 1.7 0.00011 21.7 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF1741) Abhydrolase_6 PF12697.2 OAJ27707.1 - 1.4e-13 51.2 15.4 6.7e-09 35.9 0.9 4.1 4 0 0 4 4 4 2 Alpha/beta hydrolase family DUF1057 PF06342.7 OAJ27707.1 - 0.64 8.7 0.0 0.98 8.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) GRIM-19 PF06212.7 OAJ27708.1 - 6.6e-33 113.1 0.0 7.7e-33 112.9 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein CDP-OH_P_transf PF01066.16 OAJ27709.1 - 3.7e-19 68.9 4.8 3.7e-19 68.9 3.4 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GMC_oxred_C PF05199.8 OAJ27710.1 - 3.7e-11 43.4 0.0 4.1e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase R3H PF01424.17 OAJ27711.1 - 8e-12 44.6 0.8 4e-11 42.4 0.1 2.2 2 0 0 2 2 2 1 R3H domain RRM_6 PF14259.1 OAJ27711.1 - 8.2e-10 38.5 0.1 1.6e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ27711.1 - 1.3e-06 27.9 0.0 3e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ27711.1 - 4e-06 26.5 0.1 8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAC PF01849.13 OAJ27712.1 - 1.8e-21 75.3 0.0 5.3e-21 73.9 0.0 1.8 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 OAJ27712.1 - 0.0074 16.1 0.0 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Striatin PF08232.7 OAJ27713.1 - 1.2e-40 139.0 0.0 6.9e-39 133.2 0.0 4.9 5 0 0 5 5 5 2 Striatin family DAGAT PF03982.8 OAJ27715.1 - 2.3e-94 315.4 0.0 1.3e-49 168.5 0.0 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase Glyco_trans_2_3 PF13632.1 OAJ27715.1 - 0.021 14.5 1.7 1.8 8.2 0.1 2.9 3 0 0 3 3 3 0 Glycosyl transferase family group 2 Urm1 PF09138.6 OAJ27716.1 - 4.5e-32 110.0 0.0 7e-32 109.4 0.0 1.3 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) His_Phos_1 PF00300.17 OAJ27716.1 - 7.2e-25 87.9 0.2 3.6e-24 85.6 0.1 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ThiS PF02597.15 OAJ27716.1 - 0.018 15.4 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 ThiS family LRR_4 PF12799.2 OAJ27717.1 - 6.7e-12 44.7 2.2 9.6e-11 41.0 0.2 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ27717.1 - 5e-11 42.1 1.8 1e-10 41.1 1.2 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 OAJ27717.1 - 3.4e-08 32.4 3.8 0.1 12.6 0.1 4.1 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 OAJ27717.1 - 6.1e-05 22.5 3.5 1.8 9.1 0.1 4.1 3 0 0 3 3 3 2 Leucine rich repeat Pkinase PF00069.20 OAJ27718.1 - 4.5e-30 104.6 0.0 3.7e-19 68.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ27718.1 - 3.2e-13 49.3 0.0 1.3e-08 34.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ27718.1 - 0.002 17.1 0.0 0.73 8.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RVT_3 PF13456.1 OAJ27719.1 - 0.0019 17.9 0.1 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like DNA_pol_viral_C PF00336.13 OAJ27719.1 - 0.017 14.4 0.1 0.031 13.5 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain COesterase PF00135.23 OAJ27720.1 - 2.5e-34 118.9 0.4 4.6e-34 118.0 0.3 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ27720.1 - 9.3e-07 28.6 0.0 2.1e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ27720.1 - 0.0041 16.8 0.1 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ27720.1 - 0.077 12.1 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Phage_integrase PF00589.17 OAJ27721.1 - 0.00031 20.4 0.0 0.00065 19.4 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family ATP_bind_1 PF03029.12 OAJ27722.1 - 1.1e-72 244.4 0.0 1.3e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 OAJ27722.1 - 4.1e-05 24.3 0.0 0.00011 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 OAJ27722.1 - 0.0054 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_19 PF13245.1 OAJ27722.1 - 0.015 14.9 0.0 0.048 13.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 OAJ27722.1 - 0.039 13.8 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 OAJ27722.1 - 0.04 13.8 0.6 0.26 11.2 0.4 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 OAJ27722.1 - 0.058 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 OAJ27722.1 - 0.061 12.7 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 OAJ27722.1 - 0.07 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 ArgK protein SRP54 PF00448.17 OAJ27722.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain STE PF02200.11 OAJ27725.1 - 6.3e-35 119.6 0.1 1.1e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor WD40 PF00400.27 OAJ27726.1 - 2.6e-33 112.6 15.0 5.4e-07 29.2 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat RAP1 PF07218.6 OAJ27726.1 - 4 5.4 4.0 8.1 4.3 2.8 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Abhydrolase_1 PF00561.15 OAJ27727.1 - 2e-17 63.5 0.0 2.4e-12 46.9 0.0 3.0 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 OAJ27727.1 - 3.6e-12 46.0 0.0 7.1e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 OAJ27727.1 - 2.5e-11 43.9 0.0 2e-10 40.9 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ27727.1 - 0.012 15.4 0.0 0.042 13.6 0.0 1.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family Glyco_hydro_8 PF01270.12 OAJ27728.1 - 1.7e-37 128.9 0.0 2e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 Peptidase_S29 PF02907.10 OAJ27728.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease GTP_EFTU PF00009.22 OAJ27730.1 - 6.3e-39 133.3 0.0 9.9e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 OAJ27730.1 - 2.8e-27 94.6 0.0 6.2e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 OAJ27730.1 - 2.2e-19 69.1 0.0 6.2e-19 67.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus Miro PF08477.8 OAJ27730.1 - 8.5e-08 32.7 0.0 1.9e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 OAJ27730.1 - 2.8e-07 30.5 1.5 4e-07 30.0 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAJ27730.1 - 1.2e-06 28.5 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 OAJ27730.1 - 7.1e-05 22.5 0.1 0.00015 21.5 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.17 OAJ27730.1 - 0.00063 19.1 0.0 0.0018 17.6 0.0 1.8 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.18 OAJ27730.1 - 0.048 13.4 0.2 6.7 6.4 0.0 2.3 1 1 1 2 2 2 0 Dynamin family SRPRB PF09439.5 OAJ27730.1 - 0.089 12.0 0.2 0.29 10.3 0.0 1.9 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Spo7 PF03907.8 OAJ27731.1 - 7.8e-10 38.7 0.2 0.00054 19.6 0.0 2.1 2 0 0 2 2 2 2 Spo7-like protein MARVEL PF01284.18 OAJ27731.1 - 0.62 9.8 8.3 0.14 11.9 0.5 2.6 3 0 0 3 3 3 0 Membrane-associating domain DUF3989 PF13150.1 OAJ27731.1 - 0.64 9.5 5.9 4.8 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) Nop14 PF04147.7 OAJ27732.1 - 0.046 11.6 7.1 0.055 11.3 5.0 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 OAJ27732.1 - 3.6 7.0 10.3 6.2 6.3 1.9 2.2 2 0 0 2 2 2 0 Nucleoplasmin Cut8_N PF14482.1 OAJ27732.1 - 3.7 7.6 12.3 0.27 11.2 1.6 3.4 2 1 1 3 3 3 0 Cut8 proteasome-binding domain Serglycin PF04360.7 OAJ27733.1 - 0.083 12.6 1.7 0.095 12.4 0.2 1.9 2 0 0 2 2 2 0 Serglycin PSK_trans_fac PF07704.6 OAJ27733.1 - 4.7 7.9 6.4 3.7 8.3 0.1 2.8 3 0 0 3 3 3 0 Rv0623-like transcription factor OPT PF03169.10 OAJ27735.1 - 2.2e-146 488.9 35.0 1e-145 486.6 24.2 1.8 1 1 0 1 1 1 1 OPT oligopeptide transporter protein CENP-T PF15511.1 OAJ27735.1 - 0.046 12.9 4.0 0.066 12.4 2.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BofA PF07441.6 OAJ27735.1 - 0.12 12.3 7.1 0.029 14.3 1.8 2.3 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA Spt5-NGN PF03439.8 OAJ27737.1 - 3e-20 71.7 0.1 8.1e-20 70.3 0.0 1.8 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 OAJ27737.1 - 1.1e-10 40.7 17.4 0.004 16.8 0.1 5.2 5 0 0 5 5 5 4 KOW motif Spt5_N PF11942.3 OAJ27737.1 - 1.9e-10 41.2 10.9 1.9e-10 41.2 7.6 3.8 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal FHA PF00498.21 OAJ27738.1 - 0.00046 20.2 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 FHA domain Zn_clus PF00172.13 OAJ27739.1 - 1.4e-05 24.8 10.2 2.2e-05 24.2 7.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cutinase PF01083.17 OAJ27740.1 - 9.6e-24 84.0 0.0 1.2e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ27740.1 - 8.5e-05 22.2 0.0 0.00017 21.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 OAJ27740.1 - 0.0021 17.5 0.1 0.0039 16.7 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase Abhydrolase_6 PF12697.2 OAJ27740.1 - 0.0055 16.6 0.0 0.0059 16.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 OAJ27740.1 - 0.04 13.3 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_9 PF10081.4 OAJ27740.1 - 0.1 11.2 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Cutinase PF01083.17 OAJ27741.1 - 3.5e-28 98.5 0.0 8.1e-28 97.3 0.0 1.5 1 1 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ27741.1 - 0.0008 19.0 0.0 0.00099 18.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 OAJ27741.1 - 0.0024 17.3 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PE-PPE PF08237.6 OAJ27741.1 - 0.028 13.8 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_9 PF10081.4 OAJ27741.1 - 0.028 13.1 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family DUF676 PF05057.9 OAJ27741.1 - 0.058 12.6 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.7 OAJ27741.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase Thioesterase PF00975.15 OAJ27741.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF3684 PF12449.3 OAJ27743.1 - 6.2e-284 944.6 0.0 9.2e-266 884.4 0.0 4.4 2 2 0 2 2 2 2 Protein of unknown function (DUF3684) DUF4112 PF13430.1 OAJ27744.1 - 6.8e-28 96.6 0.1 9e-28 96.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Sec16_C PF12931.2 OAJ27745.1 - 3.2e-71 240.3 0.0 7.1e-71 239.2 0.0 1.6 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 OAJ27745.1 - 5.1e-21 74.8 0.0 1.1e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Tyr_Deacylase PF02580.11 OAJ27746.1 - 9.4e-46 155.3 0.2 1.2e-44 151.7 0.2 1.9 1 1 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase E1-E2_ATPase PF00122.15 OAJ27747.1 - 3.2e-65 219.3 3.1 3.2e-65 219.3 2.2 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAJ27747.1 - 5.7e-35 120.4 2.7 5.7e-35 120.4 1.9 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ27747.1 - 3.8e-30 105.9 0.0 1.3e-28 100.8 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ27747.1 - 1.9e-17 62.9 0.0 3.8e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 OAJ27747.1 - 1.2e-14 53.5 0.0 1.2e-14 53.5 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 OAJ27747.1 - 3e-12 47.1 0.1 9.1e-12 45.5 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ27747.1 - 3e-07 30.3 0.1 1.1e-05 25.2 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.4 OAJ27747.1 - 9.2 4.7 8.0 2.3 6.7 0.1 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Pkinase PF00069.20 OAJ27748.1 - 9.1e-42 142.9 0.0 4e-39 134.3 0.0 3.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ27748.1 - 2.8e-23 82.3 0.0 1.4e-19 70.2 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 OAJ27748.1 - 0.0036 16.3 0.0 0.36 9.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Dynamin_N PF00350.18 OAJ27749.1 - 1.4e-16 60.7 0.0 3.5e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 OAJ27749.1 - 9.4e-11 41.6 0.0 4.6e-10 39.4 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAJ27749.1 - 4.5e-08 32.7 0.4 8e-07 28.6 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 OAJ27749.1 - 0.00051 20.5 0.0 0.092 13.2 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein IIGP PF05049.8 OAJ27749.1 - 0.0034 16.2 0.2 0.014 14.1 0.0 1.9 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 OAJ27749.1 - 0.0078 15.7 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FeoB_N PF02421.13 OAJ27749.1 - 0.1 11.8 0.2 7.1 5.8 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.4 OAJ27749.1 - 0.15 11.5 0.1 7.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NPV_P10 PF05531.7 OAJ27749.1 - 0.16 12.2 6.3 22 5.4 0.1 4.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Proteasome PF00227.21 OAJ27750.1 - 8.3e-38 129.5 0.0 9.4e-38 129.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Zn_clus PF00172.13 OAJ27751.1 - 3.9e-06 26.6 9.9 8.1e-06 25.6 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_ligase_OB_2 PF14743.1 OAJ27752.1 - 3.7e-29 100.2 0.3 7.9e-29 99.1 0.2 1.6 2 0 0 2 2 2 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.16 OAJ27752.1 - 1.2e-09 37.7 0.0 1.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain TraV PF09676.5 OAJ27753.1 - 4.4 8.0 8.9 6.2 7.5 6.2 1.3 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) TRAUB PF08164.7 OAJ27753.1 - 5.3 7.2 12.3 17 5.5 7.7 2.2 1 1 1 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal TP53IP5 PF15331.1 OAJ27753.1 - 7.7 6.3 11.3 9.1 6.1 7.8 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Sox_N PF12444.3 OAJ27753.1 - 7.9 7.6 10.6 6.5 7.9 6.1 1.7 1 1 1 2 2 2 0 Sox developmental protein N terminal Methyltransf_11 PF08241.7 OAJ27754.1 - 2.5e-10 40.7 0.0 1.3e-09 38.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ27754.1 - 1e-06 29.2 0.0 2.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ27754.1 - 2.4e-06 27.9 0.0 0.00011 22.5 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ27754.1 - 1.2e-05 25.5 0.0 6.4e-05 23.2 0.0 2.2 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ27754.1 - 2.2e-05 24.4 0.1 0.00012 22.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ27754.1 - 0.00017 21.3 0.0 0.0006 19.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ27754.1 - 0.0053 16.3 0.0 0.13 11.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain ELFV_dehydrog PF00208.16 OAJ27755.1 - 4.3e-46 157.4 0.0 6.6e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 OAJ27755.1 - 1.8e-20 72.1 0.1 1.3e-14 52.6 0.0 2.3 3 0 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 OAJ27755.1 - 0.0013 18.2 0.0 0.0033 17.0 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain UQ_con PF00179.21 OAJ27756.1 - 1.1e-39 135.0 0.0 1.4e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 OAJ27756.1 - 2.4e-21 75.0 0.1 3.5e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Gly-zipper_OmpA PF13436.1 OAJ27756.1 - 0.0035 17.0 11.9 0.0053 16.4 8.3 1.2 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain DUF1421 PF07223.6 OAJ27756.1 - 0.02 14.7 0.4 0.026 14.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) UBA_2 PF08587.6 OAJ27756.1 - 0.087 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Sporozoite_P67 PF05642.6 OAJ27756.1 - 0.51 8.1 6.4 0.66 7.7 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Meth_synt_2 PF01717.13 OAJ27757.1 - 3e-144 479.9 0.0 1.2e-136 454.9 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 OAJ27757.1 - 5.3e-121 403.6 0.0 2.8e-109 365.1 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Exo70 PF03081.10 OAJ27758.1 - 4.9e-52 176.9 0.0 5.1e-50 170.3 0.0 2.2 2 0 0 2 2 2 2 Exo70 exocyst complex subunit Vps52 PF04129.7 OAJ27758.1 - 0.011 14.2 0.1 0.12 10.8 0.0 2.4 3 0 0 3 3 3 0 Vps52 / Sac2 family Baculo_PEP_C PF04513.7 OAJ27758.1 - 0.038 13.8 0.2 0.97 9.2 0.0 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PaREP1 PF05942.6 OAJ27758.1 - 0.085 12.7 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family DUF2951 PF11166.3 OAJ27758.1 - 0.11 12.3 0.1 0.34 10.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) PROL5-SMR PF15621.1 OAJ27759.1 - 1.4 9.3 9.9 2.2 8.7 6.9 1.3 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family RNase_H PF00075.19 OAJ27761.1 - 1.5e-25 90.0 0.0 2e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 OAJ27761.1 - 2.7e-17 62.5 0.1 4.8e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin TPR_10 PF13374.1 OAJ27762.1 - 0.028 14.3 0.5 0.028 14.3 0.4 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Pox_P4B PF03292.9 OAJ27763.1 - 0.41 8.5 0.1 0.61 7.9 0.1 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein SDA1 PF05285.7 OAJ27763.1 - 0.47 9.6 16.5 1.2 8.4 11.4 1.6 1 0 0 1 1 1 0 SDA1 DUF3827 PF12877.2 OAJ27763.1 - 0.85 7.6 3.5 1.5 6.8 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) ATP-synt_DE PF00401.15 OAJ27764.1 - 0.13 12.1 4.0 0.21 11.5 2.8 1.3 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain SR-25 PF10500.4 OAJ27764.1 - 0.13 11.7 1.8 0.14 11.6 0.3 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cellulase PF00150.13 OAJ27765.1 - 3.5e-10 39.5 2.1 7.1e-10 38.5 1.4 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Serglycin PF04360.7 OAJ27765.1 - 0.02 14.5 0.9 0.02 14.5 0.6 2.2 2 0 0 2 2 2 0 Serglycin MAD PF05557.8 OAJ27766.1 - 0.45 8.5 16.3 0.71 7.8 11.3 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Whi5 PF08528.6 OAJ27767.1 - 6.4e-10 38.3 0.0 1e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Whi5 like PGP_phosphatase PF09419.5 OAJ27768.1 - 7.2e-40 136.0 0.0 1.4e-35 122.1 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase FAD_binding_3 PF01494.14 OAJ27768.1 - 5.9e-16 58.4 3.9 1.4e-06 27.6 0.2 3.3 3 0 0 3 3 3 3 FAD binding domain Lycopene_cycl PF05834.7 OAJ27768.1 - 0.0005 19.0 0.0 0.56 9.0 0.0 2.5 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAJ27768.1 - 0.00086 19.2 0.2 0.014 15.3 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAJ27768.1 - 0.073 13.4 0.1 0.66 10.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 OAJ27768.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Atrophin-1 PF03154.10 OAJ27769.1 - 0.00011 20.5 8.7 0.00012 20.4 6.0 1.1 1 0 0 1 1 1 1 Atrophin-1 family DUF3048 PF11258.3 OAJ27769.1 - 0.041 13.0 2.3 0.044 12.8 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) STAG PF08514.6 OAJ27769.1 - 0.21 11.2 2.3 0.34 10.6 1.6 1.4 1 1 0 1 1 1 0 STAG domain Conotoxin PF02950.12 OAJ27769.1 - 0.23 12.2 1.2 0.61 10.9 0.5 1.9 1 1 1 2 2 2 0 Conotoxin DUF2514 PF10721.4 OAJ27769.1 - 0.45 10.1 15.8 0.51 10.0 11.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) DUF2956 PF11169.3 OAJ27769.1 - 0.5 10.3 7.0 0.84 9.6 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF1682 PF07946.9 OAJ27769.1 - 1.3 7.8 8.5 1.6 7.5 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4337 PF14235.1 OAJ27769.1 - 3.6 7.4 6.5 5.2 6.8 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2058 PF09831.4 OAJ27769.1 - 5.5 6.8 9.9 7.6 6.3 6.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF2217 PF10265.4 OAJ27769.1 - 8.1 5.0 8.7 12 4.5 6.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Fringe PF02434.11 OAJ27770.1 - 8.7e-09 34.9 0.0 1.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Fringe-like RRM_1 PF00076.17 OAJ27772.1 - 1.8e-55 184.4 0.0 2.9e-17 62.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ27772.1 - 6.4e-43 144.5 0.0 4.7e-14 52.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ27772.1 - 3.1e-21 74.9 0.0 2.4e-07 30.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ27772.1 - 5.5e-06 26.1 0.0 0.29 10.9 0.0 3.3 3 0 0 3 3 3 3 RNA binding motif Limkain-b1 PF11608.3 OAJ27772.1 - 0.043 13.5 1.5 7.2 6.4 0.0 3.8 4 2 0 4 4 4 0 Limkain b1 ATP-grasp_2 PF08442.5 OAJ27772.1 - 0.052 12.9 0.0 5.5 6.3 0.0 2.7 3 0 0 3 3 3 0 ATP-grasp domain ArsA_ATPase PF02374.10 OAJ27773.1 - 2.8e-108 361.5 0.1 3.3e-108 361.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 OAJ27773.1 - 1.2e-13 50.9 0.2 1.8e-13 50.3 0.1 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 OAJ27773.1 - 6.4e-08 32.6 0.0 1.6e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 OAJ27773.1 - 1.7e-05 24.1 0.0 7.1e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 OAJ27773.1 - 0.00057 19.3 0.5 0.0046 16.4 0.1 2.2 1 1 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 OAJ27773.1 - 0.0042 16.2 0.0 0.0076 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 OAJ27773.1 - 0.0054 16.1 0.1 0.015 14.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain YhjQ PF06564.7 OAJ27773.1 - 0.0061 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 YhjQ protein AAA_18 PF13238.1 OAJ27773.1 - 0.019 15.2 0.0 0.058 13.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 OAJ27773.1 - 0.02 14.9 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 OAJ27773.1 - 0.026 14.2 0.1 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain PhoH PF02562.11 OAJ27773.1 - 0.053 12.7 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 OAJ27773.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 OAJ27773.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.17 OAJ27773.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Alba PF01918.16 OAJ27775.1 - 0.00026 20.5 0.0 0.00045 19.7 0.0 1.3 1 0 0 1 1 1 1 Alba SNARE_assoc PF09335.6 OAJ27776.1 - 2.2e-16 60.1 7.2 2.2e-16 60.1 5.0 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein adh_short PF00106.20 OAJ27777.1 - 4.7e-16 59.1 0.8 6e-14 52.3 0.6 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ27777.1 - 1.6e-06 28.1 0.2 5.5e-06 26.3 0.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ27777.1 - 2.5e-05 24.0 0.1 6.6e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 KR domain ubiquitin PF00240.18 OAJ27777.1 - 0.038 13.3 0.1 0.071 12.5 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin family NAD_binding_10 PF13460.1 OAJ27777.1 - 0.059 13.3 0.1 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding Methyltransf_16 PF10294.4 OAJ27778.1 - 4e-06 26.3 0.0 5.2e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Cellulase PF00150.13 OAJ27780.1 - 1.6e-16 60.3 0.1 3.3e-16 59.3 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.13 OAJ27781.1 - 1.1e-14 54.2 9.6 4e-14 52.4 6.7 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) tRNA-synt_2 PF00152.15 OAJ27782.1 - 2.1e-102 342.3 0.0 8.7e-53 179.2 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAJ27782.1 - 4.9e-08 32.7 0.0 8.8e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 OAJ27782.1 - 0.0027 17.3 0.0 0.44 10.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Ebola_NP PF05505.7 OAJ27783.1 - 0.57 8.1 4.9 0.64 8.0 3.4 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein SDA1 PF05285.7 OAJ27783.1 - 1.3 8.1 12.1 1.5 8.0 8.4 1.1 1 0 0 1 1 1 0 SDA1 Transposase_21 PF02992.9 OAJ27784.1 - 1.1e-20 73.7 0.0 1.7e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ27784.1 - 0.15 11.5 0.1 0.28 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Retrotrans_gag PF03732.12 OAJ27785.1 - 0.016 15.2 0.2 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 Retrotransposon gag protein Abhydrolase_3 PF07859.8 OAJ27786.1 - 2.6e-30 105.5 0.1 4.6e-21 75.3 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold FBP PF07299.6 OAJ27787.1 - 0.054 12.8 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) Pkinase PF00069.20 OAJ27788.1 - 1.5e-40 139.0 0.0 2.2e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ27788.1 - 4e-25 88.3 0.0 5.9e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ27788.1 - 0.0042 16.0 0.0 0.0067 15.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ27788.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 OAJ27788.1 - 0.41 9.6 0.0 0.7 8.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 OAJ27788.1 - 1.3 7.7 0.0 2 7.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 PS_Dcarbxylase PF02666.10 OAJ27789.1 - 3.1e-41 140.9 0.0 4.1e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase adh_short PF00106.20 OAJ27790.1 - 8.6e-27 94.0 0.2 1.1e-26 93.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ27790.1 - 4.1e-19 69.2 0.0 4.2e-11 43.0 0.1 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ27790.1 - 1e-17 64.4 0.2 6.5e-17 61.7 0.1 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 OAJ27790.1 - 0.00047 19.6 0.1 0.00059 19.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ27790.1 - 0.011 15.7 0.6 0.021 14.8 0.4 1.7 1 1 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 OAJ27790.1 - 0.026 14.1 1.8 0.047 13.3 1.1 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cutinase PF01083.17 OAJ27791.1 - 4.8e-30 104.6 0.0 5.7e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ27791.1 - 0.00018 21.1 0.0 0.00018 21.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ27791.1 - 0.0045 16.7 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ27791.1 - 0.013 15.3 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIP PF03583.9 OAJ27791.1 - 0.15 11.2 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Secretory lipase FtsJ PF01728.14 OAJ27792.1 - 4.4e-43 147.3 0.0 5.7e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase CwfJ_C_2 PF04676.9 OAJ27793.1 - 2.1e-13 50.5 0.1 3.8e-13 49.7 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_2 PF13696.1 OAJ27793.1 - 5.4e-10 38.5 6.4 4.7e-06 25.9 1.2 2.5 2 0 0 2 2 2 2 Zinc knuckle CwfJ_C_1 PF04677.10 OAJ27793.1 - 1.2e-06 28.1 0.0 2.9e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 zf-CCHC PF00098.18 OAJ27793.1 - 0.083 12.8 0.4 0.28 11.2 0.3 1.9 1 0 0 1 1 1 0 Zinc knuckle DFP PF04127.10 OAJ27794.1 - 6e-20 71.6 0.0 2e-12 47.1 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Amidase PF01425.16 OAJ27795.1 - 1.8e-58 198.4 0.1 2.2e-57 194.9 0.1 2.1 1 1 0 1 1 1 1 Amidase ubiquitin PF00240.18 OAJ27797.1 - 5.3e-09 35.3 0.1 9.9e-09 34.4 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 OAJ27797.1 - 5e-06 26.6 0.1 2.4e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 OAJ27797.1 - 0.00014 21.5 0.0 0.00016 21.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PI3K_rbd PF00794.13 OAJ27797.1 - 0.11 12.3 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain YukD PF08817.5 OAJ27797.1 - 0.13 12.8 0.0 0.15 12.6 0.0 1.3 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD DUF3523 PF12037.3 OAJ27798.1 - 0.1 11.5 1.8 0.14 11.1 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Oxysterol_BP PF01237.13 OAJ27800.1 - 1.3e-52 178.4 0.0 2.2e-42 144.8 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein COesterase PF00135.23 OAJ27801.1 - 5.6e-81 272.8 0.1 2.6e-72 244.2 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ27801.1 - 1.1e-05 25.1 0.0 2.7e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Prp18 PF02840.10 OAJ27802.1 - 1.3e-57 193.7 0.0 2.2e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.6 OAJ27802.1 - 3.4e-12 45.4 3.7 7.8e-12 44.2 2.5 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Rad21_Rec8_N PF04825.8 OAJ27805.1 - 5.7e-23 80.9 0.0 1.1e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 OAJ27805.1 - 8.2e-07 28.1 0.0 2.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein CCDC66 PF15236.1 OAJ27805.1 - 0.0044 16.6 0.6 0.0096 15.5 0.4 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 66 DUF2236 PF09995.4 OAJ27806.1 - 8.6e-23 80.8 3.2 8.6e-23 80.8 2.2 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Pex24p PF06398.6 OAJ27807.1 - 1.5e-24 86.4 5.3 1.5e-24 86.4 3.7 2.8 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin DUF3605 PF12239.3 OAJ27808.1 - 0.0031 17.3 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) CK1gamma_C PF12605.3 OAJ27808.1 - 0.2 12.2 4.2 0.28 11.7 0.4 2.1 1 1 1 2 2 2 0 Casein kinase 1 gamma C terminal AMP-binding PF00501.23 OAJ27809.1 - 7.3e-11 41.1 0.0 8.1e-11 40.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MBOAT_2 PF13813.1 OAJ27810.1 - 5.7e-14 51.9 0.2 3.8e-06 26.8 0.0 3.0 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family Ribophorin_I PF04597.9 OAJ27811.1 - 2e-100 336.3 0.0 8.1e-70 235.4 0.0 2.0 2 0 0 2 2 2 2 Ribophorin I WD40 PF00400.27 OAJ27811.1 - 2.8e-17 61.8 12.2 0.0035 17.1 0.0 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Polysacc_deac_1 PF01522.16 OAJ27812.1 - 1.5e-14 53.6 0.0 3.4e-14 52.5 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase Mt_ATP-synt_B PF05405.9 OAJ27813.1 - 3.5e-46 156.6 7.0 4.4e-46 156.3 4.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2730 PF10805.3 OAJ27813.1 - 0.00022 20.8 0.4 0.0004 20.0 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) DUF445 PF04286.7 OAJ27813.1 - 0.032 13.7 4.5 0.043 13.3 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Cauli_DNA-bind PF03310.8 OAJ27813.1 - 0.068 13.0 2.7 0.066 13.0 0.7 1.7 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein DUF1539 PF07560.6 OAJ27813.1 - 0.07 12.9 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) IBR PF01485.16 OAJ27814.1 - 7.3e-07 28.9 27.4 0.00048 19.9 2.7 3.6 3 0 0 3 3 3 3 IBR domain COX5A PF02284.11 OAJ27815.1 - 2.7e-41 139.9 0.4 3.6e-41 139.4 0.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va RICTOR_M PF14666.1 OAJ27816.1 - 4.8e-69 231.8 0.0 6.9e-68 228.0 0.0 2.8 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.1 OAJ27816.1 - 1.9e-49 168.2 0.0 7.7e-40 136.6 0.0 3.5 4 1 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.1 OAJ27816.1 - 9.9e-26 89.9 0.0 4.4e-25 87.8 0.0 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 OAJ27816.1 - 2.2e-25 88.3 0.2 5.5e-24 83.8 0.0 3.1 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 OAJ27816.1 - 0.00036 20.2 0.0 0.0008 19.1 0.0 1.6 1 0 0 1 1 1 1 Hr1 repeat HEAT PF02985.17 OAJ27816.1 - 0.18 12.0 0.5 2.8 8.2 0.2 3.0 2 0 0 2 2 2 0 HEAT repeat Coa1 PF08695.5 OAJ27817.1 - 1.3e-30 105.3 0.0 1.8e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF1604 PF07713.8 OAJ27818.1 - 1.2e-32 111.5 9.2 1e-29 102.1 6.4 2.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 OAJ27818.1 - 3.7e-05 23.4 0.4 0.00015 21.4 0.0 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 OAJ27818.1 - 0.0088 15.8 4.5 0.011 15.5 0.0 3.2 3 0 0 3 3 3 1 DExH-box splicing factor binding site GPI-anchored PF10342.4 OAJ27819.1 - 4.5e-06 27.0 0.0 9.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family WD40 PF00400.27 OAJ27820.1 - 0.28 11.1 2.5 25 4.9 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Sld5 PF05916.6 OAJ27821.1 - 0.00013 22.2 2.0 0.00015 21.9 0.0 1.9 2 0 0 2 2 2 1 GINS complex protein 4HBT_3 PF13622.1 OAJ27822.1 - 5e-25 88.7 2.6 6.8e-25 88.2 1.8 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 OAJ27822.1 - 0.00066 19.3 0.0 0.002 17.7 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA thioesterase zf-UBR PF02207.15 OAJ27823.1 - 0.07 12.8 0.8 0.13 11.9 0.6 1.5 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) TF_Zn_Ribbon PF08271.7 OAJ27823.1 - 0.22 10.8 2.3 0.23 10.8 0.5 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding Elf1 PF05129.8 OAJ27823.1 - 0.41 10.3 7.9 0.096 12.3 2.6 2.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DUF2397 PF09660.5 OAJ27823.1 - 5.7 5.4 9.1 0.16 10.5 2.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2397) SSF PF00474.12 OAJ27824.1 - 5.1e-24 84.6 34.4 5.1e-24 84.6 23.9 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family Mid2 PF04478.7 OAJ27824.1 - 1.3 8.3 3.8 61 2.9 0.1 3.5 3 0 0 3 3 3 0 Mid2 like cell wall stress sensor ABC_tran PF00005.22 OAJ27825.1 - 3.2e-41 140.8 0.0 2.7e-26 92.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 OAJ27825.1 - 1.7e-40 139.1 29.8 4.3e-25 88.6 9.2 3.5 4 0 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.14 OAJ27825.1 - 1.7e-08 33.9 2.9 0.011 15.0 0.0 4.5 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAJ27825.1 - 2.6e-05 24.6 0.0 0.19 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAJ27825.1 - 0.00011 21.6 0.2 0.14 11.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 OAJ27825.1 - 0.0026 17.2 1.2 0.57 9.5 0.3 3.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAJ27825.1 - 0.0088 16.1 1.6 3.8 7.6 0.0 3.6 4 0 0 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.13 OAJ27825.1 - 0.0088 15.5 0.1 2.5 7.5 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 OAJ27825.1 - 0.0098 15.7 0.2 0.0098 15.7 0.2 1.8 2 0 0 2 2 1 1 Domain of unknown function DUF87 AAA_10 PF12846.2 OAJ27825.1 - 0.015 14.7 0.6 3.3 7.0 0.1 2.8 2 1 0 3 3 3 0 AAA-like domain AAA_16 PF13191.1 OAJ27825.1 - 0.034 14.1 1.5 0.23 11.4 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 OAJ27825.1 - 0.044 13.9 0.4 4.6 7.4 0.1 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 OAJ27825.1 - 0.059 13.2 0.3 13 5.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 OAJ27825.1 - 0.067 13.6 1.3 3.4 8.1 0.2 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 OAJ27825.1 - 0.15 12.9 0.3 0.58 10.9 0.0 2.2 2 0 0 2 2 1 0 AAA domain ATP-synt_ab PF00006.20 OAJ27825.1 - 0.16 11.4 0.7 0.46 9.9 0.1 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 OAJ27825.1 - 0.17 11.0 0.3 15 4.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 OAJ27825.1 - 0.17 12.0 1.0 2.9 8.1 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_18 PF13238.1 OAJ27825.1 - 0.18 12.0 0.1 3.3 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 OAJ27825.1 - 0.19 11.6 2.8 2.4 8.0 0.0 2.9 3 1 0 3 3 3 0 AAA domain Tcp11 PF05794.8 OAJ27826.1 - 9.2e-07 27.9 0.0 0.44 9.2 0.0 3.2 3 0 0 3 3 3 3 T-complex protein 11 Sod_Fe_C PF02777.13 OAJ27827.1 - 1.4e-36 124.5 0.1 2.7e-36 123.6 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 OAJ27827.1 - 1.6e-32 111.6 3.2 3.1e-32 110.6 2.2 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ATP-synt_DE PF00401.15 OAJ27827.1 - 3 7.7 7.4 0.47 10.3 0.4 2.8 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain RRM_1 PF00076.17 OAJ27828.1 - 3.6e-58 193.0 0.0 1.2e-19 69.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ27828.1 - 1.2e-44 150.1 0.0 7.2e-14 51.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ27828.1 - 5.6e-32 109.3 0.0 1.2e-10 41.0 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAJ27828.1 - 0.0022 17.7 0.0 7.9 6.3 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 OAJ27828.1 - 0.15 12.0 0.0 26 4.8 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) TP6A_N PF04406.9 OAJ27829.1 - 3.4e-14 52.2 0.2 7.8e-14 51.0 0.0 1.7 2 0 0 2 2 2 1 Type IIB DNA topoisomerase zf-UBR PF02207.15 OAJ27830.1 - 2.3e-13 49.6 11.4 2.3e-13 49.6 7.9 3.3 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 OAJ27830.1 - 0.00018 21.1 3.0 0.00018 21.1 2.1 3.2 3 0 0 3 3 3 1 PHD-finger Sel1 PF08238.7 OAJ27832.1 - 3.6e-35 119.6 32.4 5.3e-06 26.8 0.1 8.7 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.1 OAJ27832.1 - 1.1 9.8 5.4 2.1 8.9 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Na_H_Exchanger PF00999.16 OAJ27833.1 - 1e-64 218.4 35.6 1.4e-64 218.0 24.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4366 PF14283.1 OAJ27833.1 - 0.03 13.7 0.0 4.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) zf-C2H2_4 PF13894.1 OAJ27834.1 - 1.8e-11 43.5 11.4 0.00067 19.8 0.0 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 OAJ27834.1 - 3.2e-11 42.8 11.4 0.0048 17.1 0.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAJ27834.1 - 7e-10 38.7 13.8 0.0004 20.5 1.8 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 OAJ27834.1 - 0.0044 17.1 9.2 0.13 12.4 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 OAJ27834.1 - 0.013 15.3 1.0 0.59 10.1 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAJ27834.1 - 0.053 13.6 0.2 0.053 13.6 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2HC PF01530.13 OAJ27834.1 - 0.077 12.7 4.0 6.1 6.6 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2HC type OSTMP1 PF09777.4 OAJ27834.1 - 0.13 11.3 0.3 0.24 10.5 0.2 1.3 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor zf-C2HC_2 PF13913.1 OAJ27834.1 - 0.22 11.2 0.5 0.48 10.1 0.3 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type DUF1796 PF08795.5 OAJ27834.1 - 6.4 6.3 5.7 1.3 8.6 0.6 2.0 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) FAM220 PF15487.1 OAJ27835.1 - 0.76 9.0 9.9 1.8 7.8 6.9 1.7 1 0 0 1 1 1 0 FAM220 family Pex16 PF08610.5 OAJ27836.1 - 1.3e-75 254.5 0.1 2.6e-58 197.6 0.0 3.1 2 1 0 2 2 2 2 Peroxisomal membrane protein (Pex16) RTC PF01137.16 OAJ27837.1 - 1.7e-57 193.8 0.0 2.2e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 OAJ27837.1 - 6.4e-29 99.9 0.0 1.2e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain MarR_2 PF12802.2 OAJ27837.1 - 0.1 12.3 0.2 19 5.0 0.0 2.9 2 0 0 2 2 2 0 MarR family IL13 PF03487.8 OAJ27837.1 - 0.12 12.1 0.1 0.36 10.5 0.1 1.9 1 0 0 1 1 1 0 Interleukin-13 Ribosomal_S2 PF00318.15 OAJ27838.1 - 4.1e-41 140.5 0.0 7.3e-41 139.7 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S2 HSP70 PF00012.15 OAJ27839.1 - 4.8e-237 787.6 7.4 5.9e-237 787.4 5.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAJ27839.1 - 1.2e-18 66.8 0.8 8e-18 64.1 0.5 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 OAJ27839.1 - 0.0013 17.6 1.0 0.0096 14.7 0.2 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 OAJ27839.1 - 0.0014 18.3 0.1 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 OAJ27839.1 - 0.024 13.6 0.0 0.051 12.5 0.0 1.6 1 0 0 1 1 1 0 StbA protein Hydantoinase_A PF01968.13 OAJ27839.1 - 0.053 12.6 1.6 0.12 11.4 0.1 2.3 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase QRPTase_N PF02749.11 OAJ27839.1 - 0.091 12.5 0.1 16 5.4 0.0 3.1 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain Cpn60_TCP1 PF00118.19 OAJ27840.1 - 1.9e-135 452.2 1.0 2.2e-135 452.0 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.6 OAJ27840.1 - 0.049 13.0 0.4 0.36 10.2 0.1 2.5 3 0 0 3 3 3 0 Propionate catabolism activator DUF1408 PF07193.6 OAJ27841.1 - 0.48 9.9 5.8 0.2 11.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1408) Adaptin_N PF01602.15 OAJ27842.1 - 8.5e-99 331.2 0.0 6e-98 328.4 0.0 1.9 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 OAJ27842.1 - 0.0023 17.8 0.1 0.15 11.8 0.0 3.1 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 OAJ27842.1 - 0.0048 16.7 0.3 4.3 7.3 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF2435) Ipi1_N PF12333.3 OAJ27842.1 - 0.01 15.8 0.9 0.066 13.1 0.2 2.7 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.18 OAJ27842.1 - 0.025 14.4 1.9 14 5.7 0.0 5.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat CortBP2 PF09727.4 OAJ27842.1 - 0.15 11.5 0.2 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Cortactin-binding protein-2 DLIC PF05783.6 OAJ27842.1 - 2.1 6.8 4.9 4 5.9 3.4 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) LRR_9 PF14580.1 OAJ27843.1 - 2.4e-57 193.3 0.0 3.2e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 OAJ27843.1 - 2.2e-14 52.6 1.4 7.6e-07 28.6 0.1 3.0 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ27843.1 - 3.2e-10 39.5 0.4 7.5e-09 35.2 0.2 2.8 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 OAJ27843.1 - 0.0013 18.5 2.3 12 6.3 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.28 OAJ27843.1 - 0.006 16.4 2.5 12 6.4 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 OAJ27843.1 - 0.052 13.7 3.4 56 4.6 0.0 4.5 4 0 0 4 4 4 0 Leucine rich repeat MRP-S33 PF08293.6 OAJ27844.1 - 5.3e-15 55.1 0.4 3.1e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal subunit S27 DUF3408 PF11888.3 OAJ27844.1 - 0.088 12.7 1.0 0.17 11.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Trs65 PF12735.2 OAJ27844.1 - 2.3 7.4 9.0 2.8 7.1 6.2 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 DUF2360 PF10152.4 OAJ27844.1 - 3 8.1 5.1 5.5 7.2 3.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Tim17 PF02466.14 OAJ27845.1 - 1.2e-18 67.4 0.0 1.9e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family His_Phos_2 PF00328.17 OAJ27846.1 - 1.7e-24 86.8 0.0 2.2e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 OAJ27846.1 - 0.03 14.4 0.0 0.08 13.0 0.0 1.7 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Catalase PF00199.14 OAJ27848.1 - 4.7e-153 509.4 0.4 6e-153 509.0 0.3 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 OAJ27848.1 - 3.5e-14 52.3 0.1 1.5e-13 50.3 0.0 2.2 2 0 0 2 2 2 1 Catalase-related immune-responsive TPR_2 PF07719.12 OAJ27849.1 - 3.8e-29 98.2 13.8 6.2e-05 22.6 0.1 10.0 11 0 0 11 11 11 5 Tetratricopeptide repeat Apc3 PF12895.2 OAJ27849.1 - 4.7e-25 87.5 5.2 1.5e-09 37.8 0.3 6.0 5 1 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 OAJ27849.1 - 8.5e-25 86.1 12.9 1.3e-05 24.7 0.0 7.7 6 1 2 8 8 8 5 TPR repeat TPR_1 PF00515.23 OAJ27849.1 - 3.9e-21 73.7 10.0 0.0001 21.7 0.0 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ27849.1 - 1.9e-19 69.3 11.2 7.2e-06 25.8 0.0 8.2 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ27849.1 - 5.7e-16 58.7 25.8 6.3e-07 29.8 0.0 7.7 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ27849.1 - 2.5e-15 54.9 0.0 1.3e-05 24.5 0.1 7.4 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ27849.1 - 1.7e-14 52.7 2.8 1.5 9.2 0.0 8.0 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ27849.1 - 5.4e-14 51.4 23.4 0.0032 17.9 0.4 9.4 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ27849.1 - 3.8e-13 49.5 14.7 0.19 12.0 0.1 8.7 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ27849.1 - 2.6e-08 33.7 20.5 0.78 10.3 0.1 8.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ27849.1 - 5.9e-06 25.6 9.7 15 5.6 0.0 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ27849.1 - 4.8e-05 23.1 8.2 1.5 8.8 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ27849.1 - 0.025 14.4 11.2 0.73 9.7 0.1 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat bZIP_1 PF00170.16 OAJ27850.1 - 6.9e-06 25.9 7.7 6.9e-06 25.9 5.3 2.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 OAJ27850.1 - 0.003 17.3 7.1 0.003 17.3 4.9 3.1 3 0 0 3 3 3 1 Basic region leucine zipper Serinc PF03348.10 OAJ27850.1 - 0.98 8.0 2.5 1.5 7.4 1.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4557 PF15101.1 OAJ27850.1 - 7 6.4 13.3 15 5.3 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) MBOAT_2 PF13813.1 OAJ27851.1 - 6.6e-10 38.9 2.8 2.7e-05 24.1 0.6 2.8 1 1 1 2 2 2 2 Membrane bound O-acyl transferase family adh_short PF00106.20 OAJ27852.1 - 4.4e-15 56.0 1.3 8.2e-15 55.1 0.9 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ27852.1 - 4.3e-06 26.5 0.1 9.8e-06 25.3 0.1 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ27852.1 - 2e-05 24.4 0.0 7.4e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAJ27852.1 - 0.00021 21.3 0.3 0.0011 19.0 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 OAJ27852.1 - 0.0089 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 OAJ27852.1 - 0.013 14.9 0.0 2.4 7.5 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 OAJ27852.1 - 0.021 14.9 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 OAJ27852.1 - 0.11 12.3 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.8 OAJ27852.1 - 0.13 11.4 0.1 0.68 9.1 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family WD40 PF00400.27 OAJ27853.1 - 3.3e-49 163.0 12.9 1.4e-09 37.4 0.1 9.4 10 0 0 10 10 10 8 WD domain, G-beta repeat Nup160 PF11715.3 OAJ27853.1 - 0.00013 20.2 0.6 0.0095 14.1 0.0 3.1 2 2 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAJ27853.1 - 0.0008 18.2 0.0 0.4 9.3 0.0 3.4 3 0 0 3 3 3 1 Nup133 N terminal like Nbas_N PF15492.1 OAJ27853.1 - 0.011 14.8 0.1 2.3 7.2 0.0 3.1 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF3312 PF11768.3 OAJ27853.1 - 0.016 13.5 0.0 0.028 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF4394 PF14339.1 OAJ27853.1 - 0.027 13.7 1.2 0.17 11.1 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4394) PQQ PF01011.16 OAJ27853.1 - 0.031 13.8 2.7 14 5.4 0.1 4.2 4 0 0 4 4 4 0 PQQ enzyme repeat PQQ_3 PF13570.1 OAJ27853.1 - 3.7 7.9 22.1 4.9 7.5 0.1 6.7 5 2 1 6 6 6 0 PQQ-like domain HEAT_EZ PF13513.1 OAJ27854.1 - 3.6e-20 71.8 21.3 3.7e-09 36.8 0.0 10.3 10 1 1 11 11 11 3 HEAT-like repeat HEAT_2 PF13646.1 OAJ27854.1 - 1.7e-18 66.6 7.9 1.2e-06 28.6 0.0 7.3 4 3 5 9 9 9 5 HEAT repeats HEAT PF02985.17 OAJ27854.1 - 2e-18 64.7 13.0 0.0019 18.1 0.0 9.8 10 0 0 10 10 10 4 HEAT repeat Vac14_Fab1_bd PF12755.2 OAJ27854.1 - 2.4e-11 43.8 0.0 0.0022 18.3 0.0 5.2 3 2 1 4 4 4 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 OAJ27854.1 - 1e-05 25.1 7.6 0.5 10.2 0.0 6.3 7 0 0 7 7 6 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 OAJ27854.1 - 1.1e-05 24.3 8.6 0.011 14.5 0.0 4.1 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal IBN_N PF03810.14 OAJ27854.1 - 1.2e-05 25.1 0.1 6.5e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cnd1 PF12717.2 OAJ27854.1 - 2.3e-05 24.3 0.0 0.0054 16.5 0.0 3.8 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 OAJ27854.1 - 0.0013 17.1 0.3 0.0042 15.4 0.1 1.9 2 0 0 2 2 2 1 Adaptin N terminal region ParcG PF10274.4 OAJ27854.1 - 0.0023 17.8 0.1 2.3 8.0 0.0 3.4 2 1 1 3 3 3 1 Parkin co-regulated protein DUF2435 PF10363.4 OAJ27854.1 - 0.0028 17.5 0.2 0.023 14.5 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) CLASP_N PF12348.3 OAJ27854.1 - 0.044 13.1 0.4 4.3 6.6 0.1 3.8 3 2 1 4 4 4 0 CLASP N terminal DARPP-32 PF05395.7 OAJ27854.1 - 0.046 13.8 0.2 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Proteasom_PSMB PF10508.4 OAJ27854.1 - 0.081 11.1 0.0 0.58 8.3 0.0 2.2 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit RNA_pol_3_Rpc31 PF11705.3 OAJ27854.1 - 0.082 12.8 9.2 0.14 12.1 6.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RPAP3_C PF13877.1 OAJ27854.1 - 0.087 12.8 0.0 0.39 10.7 0.0 2.2 2 0 0 2 2 1 0 Potential Monad-binding region of RPAP3 DUF3437 PF11919.3 OAJ27854.1 - 0.14 11.8 0.0 19 5.0 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Cnd3 PF12719.2 OAJ27854.1 - 0.35 9.8 1.4 1.8 7.4 0.0 2.7 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain TRM PF02005.11 OAJ27855.1 - 4.5e-115 384.5 0.0 1.1e-86 291.1 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase DUF3138 PF11336.3 OAJ27855.1 - 0.21 9.6 6.2 0.37 8.9 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FAD_binding_8 PF08022.7 OAJ27856.1 - 2.6e-16 59.4 0.0 2.5e-10 40.1 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain Ferric_reduct PF01794.14 OAJ27856.1 - 8.8e-14 51.6 14.6 8.8e-14 51.6 10.1 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 OAJ27856.1 - 1.8e-11 44.1 0.0 5.7e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Phytase-like PF13449.1 OAJ27857.1 - 1e-25 90.7 0.1 2.2e-25 89.6 0.0 1.5 1 1 0 1 1 1 1 Esterase-like activity of phytase Asp PF00026.18 OAJ27858.1 - 3.6e-73 246.5 0.4 5e-73 246.1 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ27858.1 - 4.7e-07 29.8 0.1 4.7e-07 29.8 0.1 2.5 4 0 0 4 4 4 1 Xylanase inhibitor N-terminal Epimerase PF01370.16 OAJ27859.1 - 4.5e-42 144.0 0.0 8.1e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 OAJ27859.1 - 7.1e-10 38.2 0.0 8.2e-06 24.9 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 OAJ27859.1 - 1.9e-09 36.8 0.0 4.3e-09 35.6 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 OAJ27859.1 - 3.6e-09 35.7 0.0 5.2e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 OAJ27859.1 - 1.5e-05 24.0 0.0 0.052 12.4 0.0 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 OAJ27859.1 - 0.00016 21.7 0.0 0.00036 20.5 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 OAJ27859.1 - 0.025 14.5 2.9 0.033 14.1 0.0 2.4 2 0 0 2 2 2 0 short chain dehydrogenase NmrA PF05368.8 OAJ27859.1 - 0.21 10.8 0.4 0.89 8.7 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family Lum_binding PF00677.12 OAJ27860.1 - 7.8e-27 92.9 0.0 1.2e-17 63.5 0.0 3.7 3 1 0 3 3 3 3 Lumazine binding domain Herpes_gI PF01688.12 OAJ27860.1 - 0.061 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I Sld5 PF05916.6 OAJ27861.1 - 2.6e-05 24.4 0.0 5e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 GINS complex protein DUF410 PF04190.8 OAJ27862.1 - 2.8e-26 92.6 0.2 5.9e-18 65.3 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF410) zf-DNL PF05180.7 OAJ27863.1 - 5.4e-29 99.7 0.0 8e-29 99.1 0.0 1.3 1 0 0 1 1 1 1 DNL zinc finger Ogr_Delta PF04606.7 OAJ27863.1 - 0.16 11.6 1.7 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger PRP1_N PF06424.7 OAJ27864.1 - 8.6e-44 149.0 2.9 8.6e-44 149.0 2.0 1.8 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 OAJ27864.1 - 3.4e-26 89.3 24.4 0.014 15.9 0.1 13.9 7 5 8 15 15 15 7 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ27864.1 - 1.8e-18 66.6 14.2 0.0096 16.2 0.0 8.9 7 2 1 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ27864.1 - 1.1e-17 64.1 14.5 0.0069 17.0 0.2 7.9 6 1 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ27864.1 - 5.6e-11 41.9 0.1 0.00024 20.6 0.0 6.5 6 1 0 7 7 7 1 TPR repeat TPR_2 PF07719.12 OAJ27864.1 - 4.1e-08 32.5 1.4 9.8 6.3 0.0 8.3 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ27864.1 - 1.6e-05 24.6 0.2 0.16 11.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Suf PF05843.9 OAJ27864.1 - 0.0009 19.0 0.0 1.2 8.7 0.0 4.6 6 1 0 6 6 6 1 Suppressor of forked protein (Suf) TPR_17 PF13431.1 OAJ27864.1 - 0.0022 18.0 0.0 31 5.1 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ27864.1 - 0.017 15.5 6.3 15 6.3 0.0 7.3 9 1 0 9 9 8 0 Tetratricopeptide repeat MIT PF04212.13 OAJ27864.1 - 0.02 14.7 0.3 0.56 10.1 0.0 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain NARP1 PF12569.3 OAJ27864.1 - 0.024 13.4 8.2 1.9 7.1 0.1 4.5 4 1 1 5 5 5 0 NMDA receptor-regulated protein 1 FAT PF02259.18 OAJ27864.1 - 0.047 12.6 11.9 0.24 10.3 0.3 3.9 3 1 0 3 3 3 0 FAT domain TPR_12 PF13424.1 OAJ27864.1 - 0.055 13.4 2.8 48 3.9 0.2 5.7 6 1 2 8 8 7 0 Tetratricopeptide repeat Helitron_like_N PF14214.1 OAJ27865.1 - 1.5e-65 220.4 0.1 2.7e-65 219.5 0.1 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 OAJ27865.1 - 0.017 14.6 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) tRNA_anti-codon PF01336.20 OAJ27866.1 - 0.65 9.8 3.1 1.1 9.2 0.5 2.2 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Tub_2 PF04525.7 OAJ27867.1 - 1.2e-15 57.3 0.0 1.5e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Tubby C 2 G6PD_C PF02781.11 OAJ27869.1 - 1.6e-121 404.7 0.0 2e-121 404.3 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 OAJ27869.1 - 7.7e-63 212.0 0.1 1.6e-62 210.9 0.1 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Allantoicase PF03561.10 OAJ27870.1 - 8.5e-84 278.5 0.0 7.4e-42 142.3 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_hydro PF04115.7 OAJ27870.1 - 2.5e-46 157.0 0.0 3.8e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate hydrolase DUF2985 PF11204.3 OAJ27871.1 - 1.1e-27 95.5 3.6 2.2e-27 94.6 2.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Sensor PF13796.1 OAJ27871.1 - 0.0042 16.7 0.1 0.017 14.7 0.0 2.0 1 0 0 1 1 1 1 Putative sensor DUF4255 PF14065.1 OAJ27874.1 - 0.018 14.4 0.7 0.045 13.2 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) LSM PF01423.17 OAJ27875.1 - 2e-12 46.4 0.0 2.4e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain Sec23_trunk PF04811.10 OAJ27876.1 - 1.3e-57 194.9 0.0 3.7e-51 173.8 0.0 2.1 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 OAJ27876.1 - 5.7e-22 77.0 0.0 9.8e-22 76.3 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 OAJ27876.1 - 1.3e-20 73.6 0.0 3.3e-20 72.4 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 OAJ27876.1 - 4.9e-16 57.9 5.5 9.5e-16 57.0 3.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 OAJ27876.1 - 0.0001 21.8 0.0 0.00024 20.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat TTL PF03133.10 OAJ27877.1 - 6.6e-42 143.4 0.0 1.9e-28 99.2 0.0 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family CENP-B_dimeris PF09026.5 OAJ27877.1 - 0.00046 20.3 1.0 0.001 19.2 0.7 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Nro1 PF12753.2 OAJ27877.1 - 0.0047 15.9 4.9 0.007 15.3 3.4 1.2 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 Nucleoplasmin PF03066.10 OAJ27877.1 - 0.087 12.3 6.5 0.15 11.5 4.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 OAJ27877.1 - 0.92 8.1 7.9 1.5 7.4 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BSP_II PF05432.6 OAJ27877.1 - 6.8 5.8 10.2 13 4.9 7.1 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.7 OAJ27877.1 - 7.3 4.3 7.5 9.7 3.9 5.2 1.1 1 0 0 1 1 1 0 Nop14-like family ABC2_membrane_4 PF12730.2 OAJ27878.1 - 0.0069 15.5 5.7 0.012 14.8 0.1 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF1129 PF06570.6 OAJ27878.1 - 1.2 8.4 5.4 11 5.2 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4231 PF14015.1 OAJ27878.1 - 1.9 8.4 16.6 2.7 8.0 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF1628 PF07790.6 OAJ27878.1 - 2.5 8.8 10.5 6.6 7.5 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1628) OTT_1508_deam PF14441.1 OAJ27879.1 - 8e-06 25.7 0.5 3.4e-05 23.6 0.4 1.9 1 1 0 1 1 1 1 OTT_1508-like deaminase dCMP_cyt_deam_1 PF00383.17 OAJ27879.1 - 0.002 17.7 1.2 0.0052 16.4 0.1 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.1 OAJ27879.1 - 0.0022 17.6 0.1 0.004 16.8 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase HATPase_c_2 PF13581.1 OAJ27879.1 - 0.084 12.6 0.3 0.26 11.0 0.1 1.9 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Mod_r PF07200.8 OAJ27880.1 - 0.019 14.8 0.9 0.024 14.5 0.6 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein GAF_3 PF13492.1 OAJ27882.1 - 0.019 15.0 0.0 0.26 11.3 0.0 2.7 2 1 0 2 2 2 0 GAF domain Pex14_N PF04695.8 OAJ27882.1 - 0.34 10.9 6.3 1.3 9.0 4.4 2.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region rve PF00665.21 OAJ27884.1 - 5.5e-21 74.8 0.0 1.5e-20 73.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ27884.1 - 0.0053 16.2 0.2 0.027 13.9 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Toprim_2 PF13155.1 OAJ27884.1 - 0.095 13.0 1.0 0.37 11.1 0.7 2.0 1 0 0 1 1 1 0 Toprim-like DUF87 PF01935.12 OAJ27884.1 - 0.14 11.9 2.9 0.8 9.4 2.2 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 Trehalase_Ca-bi PF07492.6 OAJ27884.1 - 0.76 9.1 4.1 17 4.8 0.2 2.6 2 0 0 2 2 2 0 Neutral trehalase Ca2+ binding domain zf-CCHC PF00098.18 OAJ27885.1 - 0.00062 19.5 3.4 0.0011 18.8 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ27885.1 - 0.0037 16.7 0.3 0.0081 15.6 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 OAJ27885.1 - 0.0048 17.3 0.0 0.015 15.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ27885.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Peptidase_M43 PF05572.8 OAJ27886.1 - 8.9e-15 54.6 0.0 1.3e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 OAJ27886.1 - 6.6e-05 23.4 0.1 0.00034 21.1 0.1 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAJ27886.1 - 0.0013 18.6 1.7 0.0034 17.3 1.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.4 OAJ27886.1 - 0.004 16.0 0.0 0.0061 15.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_2 PF13574.1 OAJ27886.1 - 0.005 16.9 1.1 0.0099 15.9 0.6 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 OAJ27886.1 - 0.0073 16.0 0.0 0.0089 15.7 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.1 OAJ27886.1 - 0.01 15.3 0.3 0.022 14.2 0.1 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Phos_pyr_kin PF08543.7 OAJ27887.1 - 2.3e-70 236.6 0.1 6.7e-53 179.4 0.1 3.2 2 1 1 3 3 3 3 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 OAJ27887.1 - 9.6e-27 94.1 0.1 1.5e-26 93.4 0.1 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.10 OAJ27887.1 - 0.0079 15.3 0.8 1 8.4 0.0 2.6 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family PfkB PF00294.19 OAJ27887.1 - 0.0092 15.1 0.0 0.32 10.0 0.0 2.6 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Enolase_N PF03952.11 OAJ27887.1 - 0.089 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Enolase, N-terminal domain NPBW PF15180.1 OAJ27887.1 - 0.1 12.2 0.4 1.8 8.2 0.1 2.4 2 0 0 2 2 2 0 Neuropeptides B and W Adaptin_N PF01602.15 OAJ27888.1 - 2.1e-141 471.8 5.3 2.5e-141 471.5 3.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 OAJ27888.1 - 4.1e-23 81.8 3.5 8.3e-23 80.9 2.5 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT PF02985.17 OAJ27888.1 - 0.0022 17.8 0.3 16 5.9 0.0 5.2 4 0 0 4 4 4 1 HEAT repeat RIX1 PF08167.7 OAJ27888.1 - 0.0046 16.6 0.3 0.056 13.1 0.0 3.0 2 1 1 3 3 3 1 rRNA processing/ribosome biogenesis TIP120 PF08623.5 OAJ27888.1 - 0.013 15.1 3.2 0.018 14.6 0.2 2.7 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 OAJ27888.1 - 0.35 10.6 6.4 0.15 11.8 0.5 2.9 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Peptidase_M43 PF05572.8 OAJ27889.1 - 3e-15 56.1 0.0 4.5e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 OAJ27889.1 - 2.6e-06 27.9 0.1 1.1e-05 25.9 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAJ27889.1 - 4e-05 23.6 1.0 5.8e-05 23.1 0.7 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 OAJ27889.1 - 0.00036 20.6 1.8 0.0006 19.9 1.2 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 OAJ27889.1 - 0.0014 18.2 0.9 0.003 17.1 0.2 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 OAJ27889.1 - 0.024 14.3 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M54 PF07998.6 OAJ27889.1 - 0.028 14.2 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 Orn_Arg_deC_N PF02784.11 OAJ27890.1 - 2.2e-35 122.0 0.0 3.2e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 OAJ27890.1 - 1.4e-15 57.0 0.0 2.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Abhydrolase_6 PF12697.2 OAJ27890.1 - 9.4e-05 22.3 0.0 0.00023 21.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family TAF8_C PF10406.4 OAJ27891.1 - 6e-07 29.4 4.6 4.9e-06 26.4 2.3 2.8 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term K_oxygenase PF13434.1 OAJ27892.1 - 1.1e-06 27.7 0.0 0.015 14.2 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 OAJ27892.1 - 0.0047 17.0 0.0 25 4.8 0.0 3.7 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase COG5 PF10392.4 OAJ27893.1 - 0.088 12.7 2.4 12 5.8 0.6 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF4201 PF13870.1 OAJ27893.1 - 0.28 10.6 5.1 0.24 10.7 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Filament PF00038.16 OAJ27893.1 - 0.3 10.5 18.4 0.8 9.1 0.1 3.1 2 1 1 3 3 3 0 Intermediate filament protein ADIP PF11559.3 OAJ27893.1 - 1.1 9.0 8.9 0.5 10.2 1.6 3.0 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Cep57_CLD_2 PF14197.1 OAJ27893.1 - 1.2 9.1 18.6 0.091 12.7 4.2 3.4 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Myosin_tail_1 PF01576.14 OAJ27893.1 - 2 6.0 29.3 0.93 7.1 4.3 3.1 2 1 1 3 3 3 0 Myosin tail CENP-F_leu_zip PF10473.4 OAJ27893.1 - 6 6.7 18.6 1.9 8.3 0.3 3.7 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HLH PF00010.21 OAJ27894.1 - 5.5e-13 48.3 0.0 2.1e-12 46.5 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tyrosinase PF00264.15 OAJ27896.1 - 1.6e-37 129.8 0.3 2.2e-37 129.3 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Peptidase_S9 PF00326.16 OAJ27897.1 - 0.091 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Tyrosinase PF00264.15 OAJ27898.1 - 6e-36 124.6 1.4 6e-36 124.6 1.0 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyrosinase PF00264.15 OAJ27900.1 - 1.7e-38 132.9 2.1 2.4e-38 132.5 1.4 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.15 OAJ27901.1 - 1.4e-35 123.4 4.1 1.8e-35 123.0 2.8 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase RAP1 PF07218.6 OAJ27902.1 - 3.6 5.5 4.1 4.8 5.1 2.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PIF1 PF05970.9 OAJ27903.1 - 2.5e-47 161.6 0.0 4.7e-47 160.6 0.0 1.4 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ27903.1 - 0.00023 20.8 0.0 0.00072 19.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ27903.1 - 0.0011 18.7 0.1 0.0037 16.9 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 OAJ27903.1 - 0.039 13.6 0.1 0.13 11.9 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 OAJ27903.1 - 0.044 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ27903.1 - 0.081 13.0 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 OAJ27903.1 - 0.26 10.7 4.7 1.2 8.6 0.2 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase MARVEL PF01284.18 OAJ27905.1 - 1.5e-06 28.1 8.8 2.3e-06 27.4 6.1 1.3 1 0 0 1 1 1 1 Membrane-associating domain WH1 PF00568.18 OAJ27906.1 - 3.8e-13 49.1 0.0 1.3e-12 47.3 0.0 1.7 1 1 0 1 1 1 1 WH1 domain PBD PF00786.23 OAJ27906.1 - 6.5e-09 36.0 0.0 1.5e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Pmp3 PF01679.12 OAJ27907.1 - 2e-21 75.4 6.8 2.3e-21 75.2 4.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Phage_int_SAM_1 PF02899.12 OAJ27908.1 - 0.062 13.4 0.0 0.28 11.3 0.0 2.0 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.17 OAJ27909.1 - 0.0025 17.5 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Leo1 PF04004.8 OAJ27912.1 - 1.2e-43 148.8 1.1 2.6e-43 147.7 0.0 2.2 2 0 0 2 2 2 1 Leo1-like protein DUF3473 PF11959.3 OAJ27912.1 - 0.2 11.0 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) Abhydrolase_6 PF12697.2 OAJ27913.1 - 8.2e-27 94.5 0.0 1.2e-26 93.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ27913.1 - 8.3e-21 74.5 0.0 4.8e-18 65.5 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ27913.1 - 1e-08 35.0 0.1 3.3e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAJ27913.1 - 0.00055 19.4 0.0 0.00055 19.4 0.0 2.0 2 1 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.11 OAJ27913.1 - 0.0019 17.6 0.1 0.32 10.4 0.0 2.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 OAJ27913.1 - 0.0033 16.6 0.0 0.099 11.8 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 OAJ27913.1 - 0.0056 15.9 0.0 2.5 7.3 0.0 2.8 2 1 0 2 2 2 2 Dienelactone hydrolase family Esterase_phd PF10503.4 OAJ27913.1 - 0.02 14.1 1.7 0.78 8.9 0.0 2.9 3 0 0 3 3 3 0 Esterase PHB depolymerase PGAP1 PF07819.8 OAJ27913.1 - 0.11 12.0 0.0 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein SR-25 PF10500.4 OAJ27913.1 - 8 5.8 14.7 5.2 6.4 1.5 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein BP28CT PF08146.7 OAJ27914.1 - 7.6e-36 123.1 0.6 3.8e-35 120.8 0.4 2.4 1 0 0 1 1 1 1 BP28CT (NUC211) domain CLASP_N PF12348.3 OAJ27914.1 - 0.044 13.1 6.8 2.1 7.6 0.2 3.6 3 0 0 3 3 3 0 CLASP N terminal RVT_1 PF00078.22 OAJ27915.1 - 2.5e-16 59.6 0.0 5.7e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ27915.1 - 0.0063 16.9 0.0 0.018 15.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ27915.1 - 0.064 13.0 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RRF PF01765.14 OAJ27916.1 - 4.5e-33 114.0 0.1 8.2e-33 113.1 0.1 1.4 1 0 0 1 1 1 1 Ribosome recycling factor Acyl-CoA_dh_C PF12806.2 OAJ27916.1 - 0.018 14.8 0.5 3.5 7.4 0.0 2.7 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like zf-CCHC PF00098.18 OAJ27917.1 - 1.3e-48 160.7 58.8 3.6e-07 29.8 3.2 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ27917.1 - 7.2e-11 41.6 31.5 0.069 12.8 0.7 7.0 4 2 3 7 7 7 6 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ27917.1 - 3.6e-10 39.3 44.4 0.014 15.0 1.2 7.0 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.1 OAJ27917.1 - 4.6e-05 23.0 14.4 0.0015 18.1 1.3 7.0 5 2 2 7 7 7 4 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ27917.1 - 0.07 12.6 0.1 0.07 12.6 0.1 6.9 4 2 3 7 7 7 0 Zinc knuckle Sporozoite_P67 PF05642.6 OAJ27918.1 - 1.2 6.9 10.4 1.4 6.6 7.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen VCBS PF13517.1 OAJ27919.1 - 9.1e-21 73.9 14.3 2e-06 28.0 0.4 5.8 3 2 3 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 OAJ27919.1 - 1.4e-13 50.1 8.3 0.00036 20.1 0.1 5.9 5 1 0 5 5 5 5 FG-GAP repeat TcdB_toxin_midN PF12256.3 OAJ27919.1 - 1.3e-05 24.6 1.1 8.6 5.7 0.0 5.2 5 0 0 5 5 5 3 Insecticide toxin TcdB middle/N-terminal region Cauli_VI PF01693.11 OAJ27920.1 - 1.5e-12 47.2 0.3 2.4e-12 46.6 0.2 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin TauD PF02668.11 OAJ27921.1 - 1.3e-34 120.0 0.1 4.4e-34 118.3 0.0 1.8 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 OAJ27921.1 - 0.00014 22.2 4.7 0.00017 21.9 0.4 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF971) SurE PF01975.12 OAJ27921.1 - 0.09 12.0 0.8 0.15 11.3 0.6 1.3 1 0 0 1 1 1 0 Survival protein SurE FAD_binding_7 PF03441.9 OAJ27922.1 - 2e-67 227.3 0.6 1.7e-49 168.4 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 OAJ27922.1 - 2.4e-35 121.7 0.0 4.1e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase zf-H2C2_2 PF13465.1 OAJ27923.1 - 4.8e-13 48.6 7.5 2.7e-05 24.2 0.0 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ27923.1 - 1.1e-08 34.9 25.2 0.00024 21.2 0.5 4.9 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ27923.1 - 2e-08 34.0 24.4 0.00019 21.4 0.0 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-BED PF02892.10 OAJ27923.1 - 0.024 14.3 0.0 0.024 14.3 0.0 3.3 3 1 1 4 4 4 0 BED zinc finger zf-C2HC_2 PF13913.1 OAJ27923.1 - 0.26 10.9 7.8 0.048 13.3 0.6 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Glyco_hydro_cc PF11790.3 OAJ27924.1 - 4.3e-50 170.3 2.0 5.4e-50 170.0 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Mito_carr PF00153.22 OAJ27926.1 - 1.4e-15 56.7 3.1 2.3e-05 23.9 0.0 5.7 6 0 0 6 6 6 5 Mitochondrial carrier protein DDE_Tnp_1_6 PF13751.1 OAJ27926.1 - 0.085 12.8 0.1 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain DUF3682 PF12446.3 OAJ27927.1 - 0.087 13.1 0.2 0.2 11.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF2360 PF10152.4 OAJ27927.1 - 0.28 11.4 2.3 0.84 9.9 1.6 1.8 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) V-ATPase_G PF03179.10 OAJ27929.1 - 0.0067 16.7 0.3 0.0067 16.7 0.2 2.2 2 0 0 2 2 2 1 Vacuolar (H+)-ATPase G subunit FAM219A PF15260.1 OAJ27929.1 - 1.2 9.4 4.6 15 5.9 0.1 2.3 1 1 0 2 2 2 0 Protein family FAM219A Peptidase_S64 PF08192.6 OAJ27929.1 - 1.5 7.0 5.5 1.5 7.0 3.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.4 OAJ27929.1 - 3.5 5.7 9.0 3.6 5.7 6.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Cyt-b5 PF00173.23 OAJ27930.1 - 0.0097 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 OAJ27930.1 - 0.013 15.0 8.1 0.021 14.2 5.6 1.5 1 0 0 1 1 1 0 Fatty acid desaturase MIS13 PF08202.6 OAJ27931.1 - 1.4e-17 63.6 0.0 1.5e-14 53.7 0.0 3.4 2 1 0 2 2 2 2 Mis12-Mtw1 protein family HEAT_2 PF13646.1 OAJ27932.1 - 1e-24 86.6 38.4 3.6e-08 33.5 0.0 13.4 9 4 3 13 13 13 5 HEAT repeats HEAT PF02985.17 OAJ27932.1 - 4.6e-23 79.1 22.0 0.01 15.8 0.0 15.7 18 0 0 18 18 18 6 HEAT repeat HEAT_EZ PF13513.1 OAJ27932.1 - 2.3e-16 59.7 47.1 0.0011 19.3 0.0 17.1 14 3 4 19 19 19 5 HEAT-like repeat Vac14_Fab1_bd PF12755.2 OAJ27932.1 - 1.1e-08 35.3 0.0 0.011 16.0 0.0 5.5 4 2 1 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 OAJ27932.1 - 4.5e-08 32.7 0.0 3e-05 23.4 0.0 4.2 3 1 1 4 4 4 1 CLASP N terminal Cohesin_HEAT PF12765.2 OAJ27932.1 - 1.8e-05 24.5 3.0 0.24 11.3 0.0 5.4 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion UME PF08064.8 OAJ27932.1 - 0.00034 20.5 0.1 7 6.6 0.0 5.7 5 1 2 7 7 7 1 UME (NUC010) domain Ecm29 PF13001.2 OAJ27932.1 - 0.012 14.0 0.6 0.43 9.0 0.0 3.1 2 1 1 3 3 3 0 Proteasome stabiliser Cnd1 PF12717.2 OAJ27932.1 - 0.043 13.6 0.0 1.7e+02 1.9 0.0 5.2 4 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.2 OAJ27932.1 - 0.11 11.5 0.1 15 4.4 0.0 3.4 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain VID27 PF08553.5 OAJ27933.1 - 4e-24 84.9 0.1 4.7e-24 84.6 0.1 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein SMN PF06003.7 OAJ27933.1 - 0.022 13.8 0.4 0.034 13.2 0.3 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) VID27 PF08553.5 OAJ27934.1 - 9.1e-244 811.3 12.4 3.7e-165 551.3 0.4 2.1 2 0 0 2 2 2 2 VID27 cytoplasmic protein Transposase_21 PF02992.9 OAJ27936.1 - 4.1e-23 81.6 0.0 7.5e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ27936.1 - 0.032 13.6 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Spindle_Spc25 PF08234.7 OAJ27937.1 - 8e-14 51.4 0.0 2.1e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 ERM PF00769.14 OAJ27937.1 - 0.03 13.8 13.9 0.057 12.9 9.7 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Macoilin PF09726.4 OAJ27937.1 - 0.04 12.2 3.8 0.048 11.9 2.6 1.1 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 OAJ27937.1 - 0.049 13.2 9.3 0.087 12.4 6.5 1.4 1 0 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 OAJ27937.1 - 0.11 12.3 11.6 0.2 11.5 8.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 OAJ27937.1 - 0.19 11.4 16.5 0.37 10.5 11.5 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 OAJ27937.1 - 0.82 8.5 7.2 1.4 7.7 5.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Creb_binding PF09030.5 OAJ27937.1 - 7.1 6.8 11.0 0.2 11.8 1.7 2.6 3 1 0 3 3 3 0 Creb binding CAF-1_p150 PF11600.3 OAJ27937.1 - 9.5 5.5 13.0 23 4.2 9.0 1.6 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal APG6 PF04111.7 OAJ27937.1 - 9.6 5.1 12.5 15 4.5 8.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Pkinase PF00069.20 OAJ27939.1 - 6.4e-56 189.3 0.0 4.1e-55 186.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ27939.1 - 1.5e-27 96.2 0.0 1.2e-18 67.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ27939.1 - 0.00011 21.2 0.2 0.02 13.8 0.0 2.5 3 0 0 3 3 3 2 Kinase-like Myc-LZ PF02344.10 OAJ27939.1 - 0.003 17.1 2.1 2.1 8.0 0.0 2.5 2 0 0 2 2 2 2 Myc leucine zipper domain APH PF01636.18 OAJ27939.1 - 0.011 15.4 0.5 0.17 11.5 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 OAJ27939.1 - 0.052 12.6 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 OAJ27939.1 - 0.074 13.5 1.5 0.15 12.6 0.0 2.4 2 0 0 2 2 2 0 Protein kinase C terminal domain RIO1 PF01163.17 OAJ27939.1 - 0.075 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family ABC_tran PF00005.22 OAJ27940.1 - 2.4e-33 115.3 0.0 5.5e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 OAJ27940.1 - 3.6e-29 102.0 7.3 4.6e-29 101.6 5.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 OAJ27940.1 - 9.2e-08 32.3 0.0 3.1e-05 24.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 OAJ27940.1 - 0.0024 17.3 0.1 0.0063 16.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ27940.1 - 0.0061 16.5 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 OAJ27940.1 - 0.013 15.7 0.0 0.12 12.5 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 OAJ27940.1 - 0.018 14.2 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAJ27940.1 - 0.031 15.0 0.0 0.069 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 OAJ27940.1 - 0.034 14.2 0.0 0.17 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 OAJ27940.1 - 0.14 12.4 1.0 0.19 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain ATP_bind_3 PF01171.15 OAJ27941.1 - 1.3e-35 122.5 0.0 3.1e-35 121.2 0.0 1.6 1 0 0 1 1 1 1 PP-loop family MMR_HSR1 PF01926.18 OAJ27941.1 - 5.7e-12 45.6 0.0 1.7e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 OAJ27941.1 - 0.00024 20.3 0.2 0.00076 18.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Asn_synthase PF00733.16 OAJ27941.1 - 0.0021 17.6 0.0 0.0046 16.4 0.0 1.6 1 0 0 1 1 1 1 Asparagine synthase AAA_28 PF13521.1 OAJ27941.1 - 0.015 15.2 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 OAJ27941.1 - 0.017 14.4 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B MobB PF03205.9 OAJ27941.1 - 0.026 14.2 0.1 0.051 13.2 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 OAJ27941.1 - 0.027 14.7 0.0 0.062 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NAD_synthase PF02540.12 OAJ27941.1 - 0.058 12.2 0.0 0.19 10.5 0.0 1.7 2 0 0 2 2 2 0 NAD synthase AAA_17 PF13207.1 OAJ27941.1 - 0.059 14.1 0.0 0.23 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 OAJ27941.1 - 0.11 11.2 0.2 0.21 10.3 0.1 1.3 1 0 0 1 1 1 0 ArgK protein AAA_29 PF13555.1 OAJ27941.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.16 OAJ27941.1 - 0.2 10.9 0.0 0.47 9.6 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family NAD_binding_8 PF13450.1 OAJ27942.1 - 9.1e-14 51.2 0.1 2.4e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 OAJ27942.1 - 6.5e-10 38.6 0.6 0.00011 21.4 0.0 3.1 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 OAJ27942.1 - 4.9e-06 26.7 0.1 0.00011 22.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ27942.1 - 1.2e-05 24.4 2.5 5.5e-05 22.2 0.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAJ27942.1 - 2.1e-05 24.3 0.1 0.0068 16.1 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 OAJ27942.1 - 9.2e-05 21.4 0.4 9.2e-05 21.4 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 OAJ27942.1 - 0.0076 16.6 0.3 0.016 15.6 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ27942.1 - 0.073 12.9 0.2 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 OAJ27942.1 - 0.21 11.1 0.1 0.35 10.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 OAJ27942.1 - 0.23 9.9 0.2 0.34 9.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 OAJ27942.1 - 0.66 8.7 1.6 0.99 8.1 1.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short PF00106.20 OAJ27943.1 - 4.4e-32 111.3 1.0 5.7e-32 110.9 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ27943.1 - 2.8e-15 56.4 0.3 3.7e-15 56.0 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ27943.1 - 2.9e-14 53.4 0.0 3.7e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAJ27943.1 - 0.00037 20.5 1.2 0.0043 17.0 0.8 2.2 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 OAJ27943.1 - 0.00049 19.8 0.4 0.0012 18.5 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 OAJ27943.1 - 0.00099 18.3 0.1 0.0024 17.0 0.1 1.7 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.5 OAJ27943.1 - 0.001 18.2 0.0 0.0014 17.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 OAJ27943.1 - 0.0022 17.4 0.1 0.0032 16.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 OAJ27943.1 - 0.0034 17.0 0.5 0.0062 16.1 0.3 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 OAJ27943.1 - 0.058 12.4 0.1 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain E2F_TDP PF02319.15 OAJ27943.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain RNA12 PF10443.4 OAJ27944.1 - 7.4e-126 420.1 0.1 1.5e-125 419.1 0.0 1.4 1 1 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 OAJ27944.1 - 0.0042 16.8 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase UCH PF00443.24 OAJ27946.1 - 2.7e-30 105.3 0.0 5.9e-30 104.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 OAJ27946.1 - 3.8e-11 42.9 0.0 6.4e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 OAJ27946.1 - 6.5e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MutS_V PF00488.16 OAJ27947.1 - 1.8e-71 240.2 0.0 1.3e-70 237.4 0.0 2.0 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAJ27947.1 - 1.3e-37 129.6 2.3 2.1e-37 128.9 1.6 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 OAJ27947.1 - 2.2e-23 82.4 0.0 6.9e-23 80.8 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 OAJ27947.1 - 6e-11 42.3 0.0 1.6e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 OAJ27947.1 - 6.4e-10 39.2 0.0 1.5e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain II zf-CCCH PF00642.19 OAJ27948.1 - 0.021 14.4 1.9 0.04 13.6 1.3 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mito_carr PF00153.22 OAJ27949.1 - 7e-49 163.5 9.3 6.2e-16 57.8 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Retrotrans_gag PF03732.12 OAJ27950.1 - 0.057 13.4 0.3 0.057 13.4 0.2 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein TMF_DNA_bd PF12329.3 OAJ27950.1 - 1.7 8.5 14.8 1.4 8.8 7.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cyclin PF08613.6 OAJ27951.1 - 7.7e-35 120.5 0.0 2e-21 76.9 0.0 2.4 2 0 0 2 2 2 2 Cyclin DUF2183 PF09949.4 OAJ27953.1 - 3e-25 88.0 0.0 5.5e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 OAJ27953.1 - 0.24 10.9 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) AAA PF00004.24 OAJ27954.1 - 1.4e-40 138.5 0.1 4.1e-40 137.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ27954.1 - 4.8e-05 23.4 2.6 0.0032 17.4 0.0 2.9 2 2 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 OAJ27954.1 - 0.00057 20.0 0.4 0.018 15.1 0.3 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAJ27954.1 - 0.00087 18.4 0.0 0.0019 17.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 OAJ27954.1 - 0.0014 17.9 0.0 0.0081 15.4 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_5 PF07728.9 OAJ27954.1 - 0.0014 18.3 0.7 0.0086 15.8 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 OAJ27954.1 - 0.0019 18.1 2.5 0.0065 16.3 0.0 2.7 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 OAJ27954.1 - 0.0022 18.7 0.1 0.0084 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ27954.1 - 0.0066 16.1 0.1 0.022 14.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 OAJ27954.1 - 0.0075 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Ribosomal_S19 PF00203.16 OAJ27954.1 - 0.0083 15.7 0.1 6.4 6.4 0.0 3.3 3 0 0 3 3 3 1 Ribosomal protein S19 Mg_chelatase PF01078.16 OAJ27954.1 - 0.012 14.7 0.1 0.039 13.0 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 OAJ27954.1 - 0.013 15.4 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 OAJ27954.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 OAJ27954.1 - 0.047 13.2 2.3 1.1 8.8 0.0 2.2 1 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 OAJ27954.1 - 0.057 12.3 0.0 0.098 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 OAJ27954.1 - 0.072 12.4 2.9 0.18 11.1 0.1 2.5 2 1 1 3 3 3 0 AAA domain G-gamma PF00631.17 OAJ27955.1 - 3e-22 78.1 0.0 3.3e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 GGL domain CBFD_NFYB_HMF PF00808.18 OAJ27956.1 - 1.4e-15 57.1 0.3 2.5e-15 56.2 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAJ27956.1 - 2e-10 40.6 0.2 3.4e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF4 PF05236.9 OAJ27956.1 - 0.093 11.9 0.5 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family SGT1 PF07093.6 OAJ27958.1 - 1.2 7.4 15.5 1.2 7.4 10.7 1.1 1 0 0 1 1 1 0 SGT1 protein MSP1_C PF07462.6 OAJ27958.1 - 1.5 7.0 9.7 2 6.7 6.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Dicty_REP PF05086.7 OAJ27958.1 - 2.9 5.5 6.8 3.4 5.3 4.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nucleoplasmin PF03066.10 OAJ27958.1 - 4.7 6.7 23.3 0.12 11.8 9.5 2.1 2 0 0 2 2 2 0 Nucleoplasmin Kelch_3 PF13415.1 OAJ27959.1 - 4.1e-31 106.4 19.5 7.5e-10 38.7 0.1 7.2 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 OAJ27959.1 - 9.4e-28 95.7 15.0 1.8e-07 30.8 0.1 7.2 6 2 0 6 6 6 5 Galactose oxidase, central domain DUF4110 PF13422.1 OAJ27959.1 - 4.6e-24 84.0 0.5 4.6e-24 84.0 0.3 3.8 4 1 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_5 PF13854.1 OAJ27959.1 - 3.2e-23 81.2 6.4 3.9e-06 26.6 0.0 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 OAJ27959.1 - 1.2e-18 66.3 10.7 2e-06 27.6 0.1 6.0 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.20 OAJ27959.1 - 5e-13 48.3 8.2 7.5e-07 28.5 0.0 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 OAJ27959.1 - 1.5e-11 43.5 3.2 0.00024 20.7 0.0 5.5 5 1 0 5 5 5 3 Kelch motif Grp1_Fun34_YaaH PF01184.14 OAJ27961.1 - 4.1e-22 78.5 12.3 5.5e-22 78.1 8.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2306 PF10067.4 OAJ27961.1 - 0.032 14.3 9.9 0.047 13.8 2.0 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) Ribosomal_L34e PF01199.13 OAJ27962.1 - 2.2e-37 127.1 4.4 2.8e-37 126.8 3.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e Cytochrome_C7 PF14522.1 OAJ27962.1 - 0.0049 16.4 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c7 FhuF_C PF11575.3 OAJ27962.1 - 0.23 11.1 2.0 8.1 6.1 0.1 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Lactamase_B_2 PF12706.2 OAJ27963.1 - 2e-25 89.4 0.0 6e-24 84.6 0.0 2.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 OAJ27963.1 - 8.2e-08 32.1 0.0 1.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DAGK_cat PF00781.19 OAJ27964.1 - 4.2e-21 74.7 0.1 8e-21 73.8 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Antimicrobial_5 PF08026.6 OAJ27964.1 - 0.048 13.5 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 Bee antimicrobial peptide Med15 PF09606.5 OAJ27965.1 - 0.00026 19.3 26.0 0.00035 18.9 18.0 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Maf1 PF09174.5 OAJ27965.1 - 0.011 15.5 5.7 0.011 15.5 3.9 2.2 2 0 0 2 2 2 0 Maf1 regulator MIP-T3 PF10243.4 OAJ27965.1 - 0.017 13.6 24.2 0.024 13.1 16.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Suf PF05843.9 OAJ27965.1 - 5.5 6.6 25.4 1 9.0 12.4 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RR_TM4-6 PF06459.7 OAJ27965.1 - 7.5 6.3 19.4 0.61 9.9 6.1 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TFIIF_alpha PF05793.7 OAJ27966.1 - 0.0004 18.9 0.0 0.0004 18.9 0.0 5.2 4 1 0 4 4 4 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) rve PF00665.21 OAJ27968.1 - 1.7e-05 24.8 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.1 OAJ27968.1 - 0.041 13.5 0.1 0.13 11.9 0.1 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.1 OAJ27968.1 - 0.042 13.3 0.1 0.087 12.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Aldo_ket_red PF00248.16 OAJ27970.1 - 4.1e-70 235.8 0.0 4.6e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_6 PF12697.2 OAJ27971.1 - 3e-30 105.8 1.2 7.2e-30 104.5 0.8 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ27971.1 - 1.1e-14 54.5 0.0 2e-14 53.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ27971.1 - 1.6e-10 40.9 0.1 1.4e-09 37.8 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family CMD PF02627.15 OAJ27971.1 - 2.7e-06 27.1 1.4 1.7e-05 24.5 0.0 2.7 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family Hydrolase_4 PF12146.3 OAJ27971.1 - 0.0086 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 OAJ27971.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 OAJ27971.1 - 0.12 11.8 0.0 0.3 10.4 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase F-box PF00646.28 OAJ27972.1 - 5.6e-10 38.6 0.7 1.4e-09 37.3 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ27972.1 - 0.0011 18.6 0.2 0.0026 17.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 OAJ27972.1 - 0.0067 16.1 0.0 0.0095 15.6 0.0 1.3 1 0 0 1 1 1 1 F-box-like domain Fun_ATP-synt_8 PF05933.8 OAJ27974.1 - 0.014 15.4 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) RINT1_TIP1 PF04437.8 OAJ27975.1 - 6.6e-40 137.0 0.0 1.8e-26 92.7 0.0 4.2 2 1 0 2 2 2 2 RINT-1 / TIP-1 family PBP1_TM PF14812.1 OAJ27975.1 - 0.11 12.8 1.1 0.29 11.4 0.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AFG1_ATPase PF03969.11 OAJ27976.1 - 4.2e-56 190.2 0.1 4e-42 144.3 0.0 3.9 3 1 0 3 3 3 3 AFG1-like ATPase AAA_16 PF13191.1 OAJ27976.1 - 3.6e-08 33.6 0.6 1.2e-07 31.8 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAJ27976.1 - 1.7e-05 25.0 0.0 0.019 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 OAJ27976.1 - 0.00012 21.8 0.0 0.033 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 OAJ27976.1 - 0.0012 19.0 0.0 0.022 14.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 OAJ27976.1 - 0.003 17.5 0.0 2.2 8.3 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 OAJ27976.1 - 0.0049 16.0 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 OAJ27976.1 - 0.0063 16.0 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 OAJ27976.1 - 0.0066 16.1 0.0 0.035 13.8 0.0 2.3 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 OAJ27976.1 - 0.03 13.7 0.4 1.4 8.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 OAJ27976.1 - 0.042 13.7 0.0 9.5 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain GATase_7 PF13537.1 OAJ27976.1 - 0.076 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase domain IstB_IS21 PF01695.12 OAJ27976.1 - 0.14 11.5 0.0 0.33 10.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 OAJ27976.1 - 0.28 9.8 0.0 16 4.0 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus SR-25 PF10500.4 OAJ27976.1 - 1.5 8.2 20.7 0.01 15.2 5.4 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Methyltransf_11 PF08241.7 OAJ27977.1 - 3e-09 37.2 0.0 5.2e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ27977.1 - 8.8e-07 28.7 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ27977.1 - 1.2e-05 25.5 0.1 2.6e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ27977.1 - 0.00015 22.3 0.2 0.00021 21.8 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ27977.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ27977.1 - 0.0016 18.8 0.0 0.005 17.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 OAJ27977.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase BCDHK_Adom3 PF10436.4 OAJ27978.1 - 1.6e-42 144.7 0.0 2.4e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 OAJ27978.1 - 2.3e-13 49.7 0.0 3.4e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAJ27978.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase F-box-like PF12937.2 OAJ27979.1 - 0.013 15.2 0.6 0.013 15.2 0.4 2.2 2 0 0 2 2 2 0 F-box-like zf-CCHC_6 PF15288.1 OAJ27982.1 - 0.013 15.1 0.6 0.041 13.5 0.4 1.8 1 0 0 1 1 1 0 Zinc knuckle DUF336 PF03928.9 OAJ27983.1 - 0.094 12.5 0.9 0.18 11.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF336) DDE_3 PF13358.1 OAJ27984.1 - 3e-29 101.6 0.0 4.8e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAJ27984.1 - 3.1e-08 34.2 1.8 0.00014 22.5 0.0 2.7 2 0 0 2 2 2 2 Homeodomain-like domain HTH_33 PF13592.1 OAJ27984.1 - 2.9e-06 26.7 0.0 8.2e-06 25.2 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix rve PF00665.21 OAJ27984.1 - 6.3e-06 26.2 0.0 1.8e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain HTH_29 PF13551.1 OAJ27984.1 - 0.00014 21.9 0.1 0.00039 20.5 0.1 1.9 1 1 0 1 1 1 1 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 OAJ27984.1 - 0.00068 18.4 0.2 0.081 11.6 0.0 2.1 2 0 0 2 2 2 2 Rhodopirellula transposase DDE domain HTH_Tnp_IS630 PF01710.11 OAJ27984.1 - 0.028 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Transposase HECT PF00632.20 OAJ27985.1 - 0.028 13.5 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) DAHP_synth_1 PF00793.15 OAJ27987.1 - 2.8e-92 308.2 0.0 3.4e-92 307.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family AMP-binding PF00501.23 OAJ27988.1 - 2.2e-66 224.0 0.0 2.7e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ27988.1 - 2.7e-10 41.0 0.0 6.9e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GATA PF00320.22 OAJ27989.1 - 2.2e-12 46.0 12.4 1.3e-06 27.6 2.2 2.5 2 0 0 2 2 2 2 GATA zinc finger Zn-ribbon_8 PF09723.5 OAJ27989.1 - 0.027 14.4 0.5 4.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 OAJ27989.1 - 0.56 9.5 9.8 0.27 10.5 0.2 3.1 2 1 0 2 2 2 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 OAJ27989.1 - 2.7 7.8 8.2 2.3 8.0 0.2 3.3 2 1 1 3 3 3 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 OAJ27989.1 - 3.7 7.2 5.4 4.9 6.8 0.3 2.8 2 2 1 3 3 3 0 Putative transposase DNA-binding domain RhoGEF PF00621.15 OAJ27990.1 - 9.2e-29 100.5 0.2 1.7e-28 99.7 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain Nucleic_acid_bd PF13820.1 OAJ27990.1 - 0.015 14.8 0.4 0.084 12.4 0.0 2.4 2 0 0 2 2 2 0 Putative nucleic acid-binding region TRAPP PF04051.11 OAJ27991.1 - 7.9e-34 116.3 0.0 9.4e-34 116.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component eIF3_N PF09440.5 OAJ27992.1 - 6.3e-40 136.4 2.2 7.9e-40 136.0 0.3 2.0 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 OAJ27992.1 - 9.4e-10 38.7 0.1 2e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.1 OAJ27992.1 - 0.0083 15.8 2.1 2 8.3 0.4 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ27992.1 - 0.81 9.7 4.1 3.5 7.7 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3628 PF12300.3 OAJ27992.1 - 5.4 7.0 22.8 11 6.0 15.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) Matrilin_ccoil PF10393.4 OAJ27993.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.7 OAJ27993.1 - 0.045 14.0 0.1 0.058 13.6 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein PTRF_SDPR PF15237.1 OAJ27993.1 - 0.061 12.7 0.1 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 PTRF/SDPR family Collagen PF01391.13 OAJ27994.1 - 0.00016 21.1 17.3 0.00016 21.1 12.0 3.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Rab5ip PF07019.7 OAJ27995.1 - 1.5 8.9 6.0 0.17 12.0 0.6 2.1 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) Nop25 PF09805.4 OAJ27997.1 - 0.85 9.6 10.5 0.21 11.6 0.4 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Peptidase_S46 PF10459.4 OAJ27997.1 - 5.5 5.2 8.0 5.9 5.1 5.6 1.0 1 0 0 1 1 1 0 Peptidase S46 K_channel_TID PF07941.6 OAJ27997.1 - 7.5 6.8 20.1 2.8 8.2 9.3 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain NAM-associated PF14303.1 OAJ27997.1 - 7.7 6.8 8.6 12 6.2 6.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain TFIIA PF03153.8 OAJ27999.1 - 0.059 13.2 15.5 0.33 10.8 5.7 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit DUF4017 PF13209.1 OAJ27999.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) DUF2933 PF11666.3 OAJ28000.1 - 0.29 10.6 0.0 0.29 10.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2933) CFEM PF05730.6 OAJ28000.1 - 0.37 10.6 5.5 0.58 10.0 3.3 1.8 1 1 0 1 1 1 0 CFEM domain Agouti PF05039.7 OAJ28000.1 - 0.4 11.0 3.8 0.83 10.0 0.5 2.2 2 0 0 2 2 2 0 Agouti protein GPI-anchored PF10342.4 OAJ28001.1 - 1.9e-10 41.1 2.5 3.5e-10 40.2 1.7 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CarbpepA_inh PF02977.10 OAJ28003.1 - 0.025 14.1 1.7 0.025 14.1 1.2 1.8 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Hydrophobin PF01185.13 OAJ28003.1 - 0.027 14.9 5.6 0.15 12.5 3.9 1.9 1 1 0 1 1 1 0 Fungal hydrophobin zf-AN1 PF01428.11 OAJ28004.1 - 3.9e-15 55.4 21.4 1.3e-10 40.9 3.6 3.1 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 OAJ28004.1 - 0.014 15.5 14.0 0.32 11.2 1.9 3.2 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain C1_4 PF07975.7 OAJ28004.1 - 0.72 9.8 9.6 2.1 8.4 0.4 2.9 2 0 0 2 2 2 0 TFIIH C1-like domain IBR PF01485.16 OAJ28004.1 - 2.9 7.8 16.8 2.1 8.3 3.3 3.0 2 1 0 2 2 2 0 IBR domain zf-trcl PF13451.1 OAJ28004.1 - 3 7.5 6.9 8.3 6.1 0.5 2.6 2 0 0 2 2 2 0 Probable zinc-binding domain RCC1 PF00415.13 OAJ28005.1 - 1.7e-16 60.1 8.1 0.00066 19.8 0.0 7.5 7 2 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ28005.1 - 5.5e-16 57.7 8.2 0.00018 20.9 0.1 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Helicase_C PF00271.26 OAJ28006.1 - 1.6e-20 72.7 0.1 1.7e-19 69.4 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ28006.1 - 2.4e-18 66.6 0.0 6.5e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ28006.1 - 6e-18 64.9 0.0 1.3e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ACT PF01842.20 OAJ28006.1 - 0.1 12.0 0.2 0.46 10.0 0.2 2.1 1 0 0 1 1 1 0 ACT domain UDPGT PF00201.13 OAJ28008.1 - 1.6e-13 50.0 0.0 2.2e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase SpoIIE PF07228.7 OAJ28010.1 - 5.9e-08 32.6 0.0 0.019 14.6 0.0 3.4 3 0 0 3 3 3 3 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 OAJ28010.1 - 4.7e-06 26.1 0.3 0.12 11.7 0.0 2.9 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C PF00481.16 OAJ28010.1 - 1.9e-05 24.1 0.0 0.00041 19.8 0.0 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C PPR_2 PF13041.1 OAJ28011.1 - 9.4e-30 102.3 0.4 1.4e-07 31.4 0.0 8.6 4 1 6 10 10 10 6 PPR repeat family PPR_3 PF13812.1 OAJ28011.1 - 1e-21 75.2 5.2 0.0064 16.6 0.0 10.9 11 0 0 11 11 11 4 Pentatricopeptide repeat domain PPR PF01535.15 OAJ28011.1 - 5e-21 73.1 1.6 0.0077 16.1 0.0 9.5 12 1 0 12 12 12 4 PPR repeat PPR_1 PF12854.2 OAJ28011.1 - 1.4e-11 43.6 5.1 0.00058 19.2 0.0 6.7 7 1 0 7 7 7 3 PPR repeat TPR_14 PF13428.1 OAJ28011.1 - 1.1e-05 25.6 10.0 9.1 7.2 0.0 7.9 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ28011.1 - 0.00071 19.1 0.0 2 8.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ28011.1 - 2.5 8.8 13.4 35 5.2 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat GTP_EFTU PF00009.22 OAJ28012.1 - 8.9e-41 139.3 0.0 1.9e-40 138.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 OAJ28012.1 - 3.2e-35 120.2 0.1 1.1e-34 118.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 OAJ28012.1 - 4.6e-29 100.0 0.0 1e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 OAJ28012.1 - 2.2e-22 78.7 0.1 5.9e-22 77.3 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 OAJ28012.1 - 2.5e-12 46.7 0.0 7.1e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Usp PF00582.21 OAJ28014.1 - 0.00075 19.7 7.3 0.021 15.0 0.0 3.8 4 0 0 4 4 4 2 Universal stress protein family UPF0081 PF03652.10 OAJ28014.1 - 0.023 14.8 0.6 0.17 12.0 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0081) Fungal_trans PF04082.13 OAJ28015.1 - 1.1e-10 40.8 0.0 1.8e-09 36.8 0.0 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 OAJ28015.1 - 7.2e-05 22.9 10.3 0.014 15.7 0.8 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type Serglycin PF04360.7 OAJ28015.1 - 0.0016 18.1 0.8 0.0016 18.1 0.6 3.8 4 0 0 4 4 4 1 Serglycin zf-C2H2_4 PF13894.1 OAJ28015.1 - 0.0025 18.0 6.0 0.37 11.2 1.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 OAJ28015.1 - 0.18 11.7 7.9 0.68 9.9 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Thi4 PF01946.12 OAJ28017.1 - 9.2e-12 44.5 0.0 1.1e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Thi4 family TPR_12 PF13424.1 OAJ28018.1 - 1.1e-06 28.4 0.9 0.00013 21.8 0.2 3.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ28018.1 - 0.0036 17.1 2.3 3.7 7.6 0.8 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat AstE_AspA PF04952.9 OAJ28018.1 - 0.0064 15.4 0.2 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family TPR_11 PF13414.1 OAJ28018.1 - 0.01 15.4 0.2 0.037 13.6 0.1 2.0 1 0 0 1 1 1 0 TPR repeat TPR_19 PF14559.1 OAJ28018.1 - 0.068 13.5 2.1 0.16 12.2 0.1 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ28018.1 - 0.11 12.5 1.2 12 6.1 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 OAJ28019.1 - 5.4e-08 32.3 12.4 7e-08 31.9 6.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ28019.1 - 1.2e-06 28.2 13.1 1.3e-05 24.9 7.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 OAJ28019.1 - 1.8e-06 27.7 9.1 1.8e-06 27.7 6.3 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 OAJ28019.1 - 4e-06 26.4 3.1 4e-06 26.4 2.1 2.1 3 0 0 3 3 2 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 OAJ28019.1 - 7.5e-06 25.8 13.6 1.4e-05 25.0 7.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ28019.1 - 1.6e-05 24.5 13.9 2.2e-05 24.1 6.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 OAJ28019.1 - 4.2e-05 23.3 4.9 0.00011 21.9 2.2 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 OAJ28019.1 - 5e-05 22.8 12.1 0.0003 20.3 6.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 OAJ28019.1 - 8.9e-05 21.8 1.0 0.00034 20.0 0.0 2.3 2 0 0 2 2 2 1 SAP domain zf-RING_UBOX PF13445.1 OAJ28019.1 - 0.00049 19.7 4.0 0.00049 19.7 2.8 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 OAJ28019.1 - 0.0033 16.9 4.8 0.0033 16.9 3.3 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Serglycin PF04360.7 OAJ28019.1 - 0.0049 16.6 0.5 0.009 15.7 0.3 1.4 1 0 0 1 1 1 1 Serglycin zf-rbx1 PF12678.2 OAJ28019.1 - 0.0066 16.5 7.3 0.047 13.8 2.9 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger Phage_Cox PF10743.4 OAJ28019.1 - 0.059 13.3 0.1 0.8 9.7 0.1 2.3 2 0 0 2 2 2 0 Regulatory phage protein cox DUF3505 PF12013.3 OAJ28019.1 - 0.077 13.2 2.5 2.6 8.3 0.0 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3505) FYVE PF01363.16 OAJ28019.1 - 0.72 9.7 10.4 6 6.8 0.1 2.6 2 0 0 2 2 2 0 FYVE zinc finger zf-MIZ PF02891.15 OAJ28019.1 - 1 8.9 11.7 3.5 7.2 5.8 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger NOB1_Zn_bind PF08772.6 OAJ28019.1 - 1.1 9.0 12.7 2.8 7.8 0.0 3.4 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf-RING_4 PF14570.1 OAJ28019.1 - 1.3 8.6 11.3 5 6.7 6.4 2.6 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DZR PF12773.2 OAJ28019.1 - 1.7 8.5 7.1 1.3 8.8 2.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon Kp4 PF09044.5 OAJ28020.1 - 0.015 15.1 0.2 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 Kp4 Pex2_Pex12 PF04757.9 OAJ28021.1 - 9.4e-26 90.6 9.6 1.5e-25 89.9 6.7 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 OAJ28021.1 - 2.9e-10 39.8 7.9 4.6e-10 39.1 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAJ28021.1 - 2.5e-09 36.7 5.7 3.8e-09 36.1 4.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAJ28021.1 - 2.2e-08 33.9 7.1 3.5e-08 33.3 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ28021.1 - 2.7e-08 33.3 4.9 4.6e-08 32.6 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ28021.1 - 4.3e-07 29.4 6.1 7e-07 28.8 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAJ28021.1 - 2.5e-06 27.0 1.1 5.1e-06 26.1 0.3 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 OAJ28021.1 - 1.1e-05 25.4 4.2 1.9e-05 24.6 2.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 OAJ28021.1 - 0.0006 19.6 2.9 0.0006 19.6 2.0 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 OAJ28021.1 - 0.0081 15.7 6.6 0.013 15.0 4.6 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 OAJ28021.1 - 0.017 14.9 2.5 0.03 14.1 1.7 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 OAJ28021.1 - 0.03 14.1 2.3 0.061 13.1 1.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.6 OAJ28021.1 - 0.052 13.2 0.3 0.091 12.4 0.2 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.1 OAJ28021.1 - 0.23 11.0 2.6 0.52 9.8 1.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 IBR PF01485.16 OAJ28021.1 - 1.1 9.1 6.4 2.6 7.9 4.4 1.6 1 1 0 1 1 1 0 IBR domain Rtf2 PF04641.7 OAJ28021.1 - 2.2 7.4 5.9 0.5 9.5 0.2 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger Btz PF09405.5 OAJ28022.1 - 1.6e-05 24.9 0.0 1.6e-05 24.9 0.0 4.6 4 1 1 5 5 5 2 CASC3/Barentsz eIF4AIII binding Daxx PF03344.10 OAJ28022.1 - 0.051 12.0 28.4 0.12 10.8 19.7 1.6 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 OAJ28022.1 - 0.39 9.9 23.4 0.66 9.2 16.2 1.3 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.7 OAJ28022.1 - 2.4 7.3 10.1 5.2 6.2 7.0 1.5 1 0 0 1 1 1 0 NOA36 protein DUF3295 PF11702.3 OAJ28024.1 - 3.4e-11 42.8 2.5 3.4e-11 42.8 1.7 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF3295) EPL1 PF10513.4 OAJ28025.1 - 1.4e-19 70.9 0.0 1.4e-19 70.9 0.0 5.0 5 1 0 5 5 5 1 Enhancer of polycomb-like Pro_isomerase PF00160.16 OAJ28026.1 - 1.4e-44 152.0 0.2 2.4e-44 151.2 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Xpo1 PF08389.7 OAJ28026.1 - 4.6e-14 52.5 0.0 2.4e-13 50.2 0.0 2.3 2 0 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.1 OAJ28026.1 - 0.0014 18.8 0.7 0.006 16.8 0.1 2.4 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 OAJ28026.1 - 0.003 17.4 0.1 0.12 12.4 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.18 OAJ28026.1 - 0.012 15.3 0.1 0.074 12.9 0.1 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat MULE PF10551.4 OAJ28027.1 - 3.2e-19 68.8 0.0 5.1e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ28027.1 - 1.1e-08 34.0 0.0 1.4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family DUF4449 PF14613.1 OAJ28028.1 - 5.8e-26 91.3 1.3 5.8e-26 91.3 0.9 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Phage_connect_1 PF05135.8 OAJ28028.1 - 5.4 7.2 7.1 21 5.3 0.2 3.2 3 0 0 3 3 3 0 Phage gp6-like head-tail connector protein UPF0029 PF01205.14 OAJ28030.1 - 8e-16 57.7 0.0 2.8e-15 55.9 0.0 2.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF605 PF04652.11 OAJ28030.1 - 0.02 14.3 36.2 0.12 11.7 16.6 2.3 2 0 0 2 2 2 0 Vta1 like Con-6 PF10346.4 OAJ28031.1 - 5.3e-09 35.3 0.8 9.6e-09 34.5 0.5 1.5 1 1 0 1 1 1 1 Conidiation protein 6 UQ_con PF00179.21 OAJ28032.1 - 8.5e-22 77.0 0.0 1.3e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ28032.1 - 0.023 14.4 0.1 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic E2 family B UEV PF05743.8 OAJ28032.1 - 0.03 14.0 0.1 0.069 12.8 0.1 1.7 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 OAJ28032.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain HALZ PF02183.13 OAJ28034.1 - 0.00026 20.6 0.0 0.00039 20.0 0.0 1.2 1 0 0 1 1 1 1 Homeobox associated leucine zipper Apolipoprotein PF01442.13 OAJ28035.1 - 0.012 15.1 2.1 0.017 14.6 1.5 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain RNF111_N PF15303.1 OAJ28035.1 - 0.045 13.2 0.6 0.045 13.2 0.4 1.6 1 1 1 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus ROF PF07073.7 OAJ28035.1 - 0.11 12.5 1.4 0.14 12.1 0.4 1.6 2 0 0 2 2 2 0 Modulator of Rho-dependent transcription termination (ROF) MFS_1 PF07690.11 OAJ28037.1 - 6.8e-42 143.4 49.5 6.8e-42 143.4 34.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ28037.1 - 1.2e-11 43.8 9.7 1.2e-11 43.8 6.7 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter SHR3_chaperone PF08229.6 OAJ28038.1 - 0.066 12.1 0.0 0.08 11.8 0.0 1.0 1 0 0 1 1 1 0 ER membrane protein SH3 Cellulase PF00150.13 OAJ28039.1 - 0.00013 21.3 0.0 0.29 10.3 0.0 2.2 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) ATP-synt_ab PF00006.20 OAJ28039.1 - 0.00028 20.4 0.0 0.0005 19.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain UPF0061 PF02696.9 OAJ28040.1 - 1.8e-07 29.8 0.1 2.4e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF2107 PF09880.4 OAJ28043.1 - 0.096 12.5 0.4 0.37 10.6 0.0 2.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2107) Glyco_hydro_30 PF02055.11 OAJ28044.1 - 6.3e-20 70.8 0.9 3.5e-19 68.3 0.6 1.9 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_tranf_2_3 PF13641.1 OAJ28047.1 - 6.1e-28 98.1 0.0 8.2e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 OAJ28047.1 - 5.8e-17 62.0 5.0 5.8e-17 62.0 3.5 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 OAJ28047.1 - 6.2e-09 35.3 0.0 9.7e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 OAJ28047.1 - 1.4e-06 28.0 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 PIF1 PF05970.9 OAJ28049.1 - 9.8e-18 64.2 0.0 1.6e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ28049.1 - 2.5e-12 46.7 0.2 1e-11 44.7 0.2 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ28049.1 - 8.8e-08 31.7 0.1 3.3e-07 29.9 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain Helitron_like_N PF14214.1 OAJ28049.1 - 0.00027 20.7 0.0 0.00092 18.9 0.0 1.9 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_16 PF13191.1 OAJ28049.1 - 0.0027 17.7 0.1 0.016 15.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 OAJ28049.1 - 0.039 14.0 0.1 0.5 10.4 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_22 PF13401.1 OAJ28049.1 - 0.047 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 OAJ28049.1 - 0.062 13.0 0.3 0.5 10.0 0.2 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 OAJ28049.1 - 0.1 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Torsin PF06309.6 OAJ28049.1 - 0.11 12.3 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 Torsin Pkinase PF00069.20 OAJ28051.1 - 2.1e-47 161.4 0.0 5.4e-47 160.1 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28051.1 - 6.9e-33 113.8 0.0 1.4e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 OAJ28051.1 - 0.0004 19.5 0.3 0.0018 17.3 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ28051.1 - 0.0065 15.4 0.2 0.02 13.8 0.0 2.0 2 1 0 2 2 2 1 Kinase-like IncA PF04156.9 OAJ28051.1 - 4.6 6.8 41.8 0.11 12.1 0.5 3.9 1 1 2 3 3 3 0 IncA protein RskA PF10099.4 OAJ28053.1 - 0.053 13.2 5.1 0.16 11.7 1.4 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA F5_F8_type_C PF00754.20 OAJ28053.1 - 0.15 11.9 1.3 1.9 8.3 0.0 3.3 5 0 0 5 5 5 0 F5/8 type C domain BNR PF02012.15 OAJ28053.1 - 5.5 7.2 27.9 15 5.9 0.0 6.6 6 0 0 6 6 6 0 BNR/Asp-box repeat E1-E2_ATPase PF00122.15 OAJ28054.1 - 8.2e-26 90.4 0.1 6.1e-25 87.5 0.1 2.2 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 OAJ28054.1 - 1.2e-25 90.8 0.8 1.7e-25 90.3 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 OAJ28054.1 - 5.6e-25 87.5 0.0 1.5e-24 86.1 0.0 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.21 OAJ28054.1 - 9.9e-22 78.4 0.0 4.9e-20 72.8 0.0 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 OAJ28054.1 - 6.5e-06 25.7 10.0 6.5e-06 25.7 6.9 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 OAJ28054.1 - 8.9e-05 22.3 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAJ28054.1 - 0.021 14.4 0.0 0.11 12.1 0.0 2.1 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAJ28054.1 - 0.021 14.2 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus NAD_kinase PF01513.16 OAJ28055.1 - 1.3e-51 175.0 0.0 1.6e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase PIF1 PF05970.9 OAJ28056.1 - 2.3e-59 201.1 0.6 2.4e-46 158.3 0.1 2.1 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 OAJ28056.1 - 2.6e-17 63.0 0.0 4.8e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ28056.1 - 4.3e-08 33.3 0.0 8.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ28056.1 - 0.00018 21.2 0.7 0.00044 19.9 0.5 1.6 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 OAJ28056.1 - 0.00031 20.8 0.0 0.0063 16.6 0.0 2.6 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 OAJ28056.1 - 0.00042 19.8 0.1 0.47 9.9 0.1 3.1 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 OAJ28056.1 - 0.00053 18.9 0.0 0.00088 18.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 OAJ28056.1 - 0.0011 18.0 0.0 0.0021 17.0 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 OAJ28056.1 - 0.0011 19.0 0.1 0.0037 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain TrwB_AAD_bind PF10412.4 OAJ28056.1 - 0.0026 16.4 0.0 0.0047 15.5 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.24 OAJ28056.1 - 0.0041 17.3 0.0 0.009 16.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 OAJ28056.1 - 0.0056 16.2 0.1 0.53 9.8 0.0 2.6 1 1 1 2 2 2 1 AAA domain PhoH PF02562.11 OAJ28056.1 - 0.01 15.0 0.0 0.025 13.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 OAJ28056.1 - 0.011 15.4 0.0 0.028 14.0 0.0 1.8 1 1 0 1 1 1 0 NACHT domain Herpes_Helicase PF02689.9 OAJ28056.1 - 0.013 13.2 0.1 0.31 8.7 0.0 2.2 2 0 0 2 2 2 0 Helicase AAA_14 PF13173.1 OAJ28056.1 - 0.014 15.3 0.0 0.084 12.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 OAJ28056.1 - 0.017 14.8 0.1 0.088 12.4 0.1 2.0 1 1 0 1 1 1 0 Archaeal ATPase IstB_IS21 PF01695.12 OAJ28056.1 - 0.023 14.1 0.0 2.9 7.2 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.2 OAJ28056.1 - 0.065 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 Sigma54_activat PF00158.21 OAJ28056.1 - 0.072 12.5 0.1 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 OAJ28056.1 - 0.089 12.5 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 OAJ28056.1 - 0.12 12.0 0.2 0.97 9.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) HTH_17 PF12728.2 OAJ28056.1 - 0.13 12.4 0.1 9.8 6.5 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain Mg_trans_NIPA PF05653.9 OAJ28057.1 - 7.5e-92 307.4 23.1 1.1e-91 306.9 16.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 OAJ28057.1 - 2.2e-05 24.5 8.4 2.2e-05 24.5 5.8 4.4 3 1 2 5 5 5 1 Multidrug resistance efflux transporter EamA PF00892.15 OAJ28057.1 - 5.1e-05 23.3 6.2 5.1e-05 23.3 4.3 3.8 3 2 1 4 4 4 1 EamA-like transporter family DUF2208 PF09973.4 OAJ28057.1 - 0.68 9.1 3.4 1.4 8.0 2.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) LRR_4 PF12799.2 OAJ28058.1 - 2.9e-49 163.9 56.2 1.3e-07 31.0 2.0 12.9 6 4 6 14 14 14 13 Leucine Rich repeats (2 copies) PP2C PF00481.16 OAJ28058.1 - 4.1e-48 163.9 0.0 7.5e-48 163.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 OAJ28058.1 - 1.6e-40 136.6 51.1 1.6e-10 40.5 0.6 9.6 4 2 8 12 12 12 11 Leucine rich repeat Guanylate_cyc PF00211.15 OAJ28058.1 - 3.4e-24 85.2 0.0 6e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 OAJ28058.1 - 1.5e-19 67.0 57.3 0.043 13.8 0.0 20.0 21 1 0 21 21 21 7 Leucine Rich Repeat LRR_7 PF13504.1 OAJ28058.1 - 1.8e-08 33.2 47.2 1.6 9.2 0.0 17.0 18 0 0 18 18 18 3 Leucine rich repeat RA PF00788.18 OAJ28058.1 - 8.5e-07 29.3 0.0 1.6e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_6 PF13516.1 OAJ28058.1 - 6.4e-06 25.7 44.5 2.1 8.6 0.1 15.2 15 0 0 15 15 15 1 Leucine Rich repeat LRR_5 PF13306.1 OAJ28058.1 - 0.0092 15.6 1.3 9.5 5.9 0.0 3.5 2 1 2 4 4 4 1 Leucine rich repeats (6 copies) COesterase PF00135.23 OAJ28059.1 - 1.6e-98 330.7 0.0 2.6e-98 330.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ28059.1 - 0.00021 20.9 0.1 0.00048 19.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAJ28059.1 - 0.0047 16.1 0.1 0.0084 15.3 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Pkinase PF00069.20 OAJ28061.1 - 1.6e-18 66.8 0.0 1e-17 64.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28061.1 - 6.5e-06 25.4 0.1 0.00051 19.1 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 OAJ28061.1 - 0.0019 17.9 1.8 0.0026 17.5 0.4 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family zf-C3HC4 PF00097.20 OAJ28062.1 - 7.1e-06 25.5 2.3 2.7e-05 23.7 0.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ28062.1 - 4.9e-05 23.0 4.5 0.00058 19.6 0.1 2.7 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 OAJ28062.1 - 0.0092 15.6 1.9 0.053 13.2 0.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAJ28062.1 - 0.18 11.4 7.6 0.26 10.9 0.3 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ28062.1 - 0.43 10.6 10.1 0.025 14.6 1.3 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 OAJ28062.1 - 2.6 7.8 9.2 17 5.2 0.1 2.7 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 OAJ28062.1 - 9.9 6.3 12.3 0.11 12.4 3.0 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type SIP1 PF04938.7 OAJ28064.1 - 4.6e-16 58.8 0.5 1.9e-12 47.0 0.1 3.0 3 0 0 3 3 3 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) PH_BEACH PF14844.1 OAJ28064.1 - 2.4 8.0 4.3 0.86 9.4 0.4 2.2 3 0 0 3 3 3 0 PH domain associated with Beige/BEACH RRM_6 PF14259.1 OAJ28065.1 - 1.2e-06 28.3 0.0 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 OAJ28065.1 - 0.00013 21.5 8.4 0.00036 20.1 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ28065.1 - 0.38 10.5 9.6 0.8 9.4 6.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 OAJ28065.1 - 4.2 7.1 10.4 9.4 5.9 7.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MAS20 PF02064.10 OAJ28066.1 - 6.9e-13 48.5 0.0 6e-12 45.5 0.0 2.0 1 1 0 1 1 1 1 MAS20 protein import receptor EutA PF06277.6 OAJ28066.1 - 1.2 7.6 5.1 1.8 7.0 3.5 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA Myosin_head PF00063.16 OAJ28067.1 - 4.2e-248 824.9 0.0 4.2e-248 824.9 0.0 2.0 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 OAJ28067.1 - 2e-06 25.8 57.0 2e-06 25.8 39.5 3.5 1 1 2 3 3 3 2 Myosin tail Myosin_N PF02736.14 OAJ28067.1 - 0.00011 21.8 0.3 0.00029 20.4 0.2 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 OAJ28067.1 - 0.0081 15.8 1.0 0.038 13.7 0.7 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 OAJ28067.1 - 0.16 12.0 0.0 0.16 12.0 0.0 4.8 4 1 1 6 6 6 0 AAA domain IQ PF00612.22 OAJ28067.1 - 0.22 11.2 4.2 0.51 10.1 0.9 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF4206 PF13901.1 OAJ28067.1 - 2.3 7.7 0.0 2.3 7.7 0.0 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4206) Sec20 PF03908.8 OAJ28068.1 - 4.5e-19 67.9 1.3 1.1e-18 66.7 0.9 1.6 1 0 0 1 1 1 1 Sec20 DUF2776 PF10951.3 OAJ28068.1 - 0.021 13.9 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) YrhK PF14145.1 OAJ28068.1 - 0.54 9.9 2.6 0.33 10.6 0.3 1.8 2 0 0 2 2 2 0 YrhK-like protein DctM PF06808.7 OAJ28068.1 - 8.8 4.7 10.3 17 3.8 4.6 2.1 2 0 0 2 2 2 0 DctM-like transporters DAHP_synth_1 PF00793.15 OAJ28069.1 - 1.4e-93 312.5 0.0 1.7e-93 312.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Aminotran_5 PF00266.14 OAJ28070.1 - 4.9e-29 101.2 0.0 7.6e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 OAJ28070.1 - 0.00066 19.5 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain RVT_2 PF07727.9 OAJ28072.1 - 6.6e-74 247.9 0.0 9.4e-74 247.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ28072.1 - 6.1e-21 74.7 0.0 1.7e-20 73.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ28072.1 - 2.2e-07 30.4 0.0 3.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ28072.1 - 0.00069 19.0 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain SPC25 PF06703.6 OAJ28073.1 - 7.1e-35 119.9 0.0 9.3e-35 119.6 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) UBN2_2 PF14227.1 OAJ28074.1 - 4.9e-13 48.6 0.0 8.3e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ28074.1 - 9.2e-09 35.1 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 OAJ28074.1 - 0.019 14.5 0.1 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type MIF4G_like PF09088.6 OAJ28076.1 - 2.8e-59 199.7 0.0 1.4e-58 197.4 0.0 2.1 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 OAJ28076.1 - 1e-34 119.9 0.4 2.5e-29 102.2 0.0 3.1 2 1 0 2 2 2 2 MIF4G like GKAP PF03359.8 OAJ28076.1 - 0.00025 20.7 0.4 0.0005 19.8 0.3 1.4 1 0 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein Myb_DNA-bind_3 PF12776.2 OAJ28077.1 - 0.00019 21.9 0.4 0.0004 20.9 0.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain NIPSNAP PF07978.8 OAJ28077.1 - 0.12 12.3 0.4 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 NIPSNAP Skp1 PF01466.14 OAJ28078.1 - 1.5e-37 127.4 1.1 2.4e-37 126.7 0.7 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 OAJ28078.1 - 7.2e-18 64.4 0.0 1.7e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Spt4 PF06093.8 OAJ28079.1 - 2.7e-29 100.8 0.1 3.1e-29 100.6 0.1 1.0 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Integrin_B_tail PF07965.7 OAJ28079.1 - 0.076 13.4 1.3 0.11 12.9 0.9 1.2 1 0 0 1 1 1 0 Integrin beta tail domain DZR PF12773.2 OAJ28079.1 - 0.078 12.8 1.5 0.13 12.0 1.0 1.3 1 0 0 1 1 1 0 Double zinc ribbon Med11 PF10280.4 OAJ28080.1 - 8.6e-05 22.5 0.0 9.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Mediator complex protein zf-CCHC PF00098.18 OAJ28082.1 - 9.6e-05 22.1 5.0 0.00019 21.1 3.5 1.5 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 OAJ28082.1 - 0.0013 18.4 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.1 OAJ28082.1 - 0.025 14.0 0.8 0.044 13.2 0.5 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ28082.1 - 0.036 13.8 1.5 0.065 12.9 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.9 OAJ28083.1 - 1.7e-79 266.2 0.0 2.7e-79 265.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ28083.1 - 3.4e-23 82.0 0.0 8.7e-23 80.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ28083.1 - 6.4e-05 22.3 0.1 0.00037 19.9 0.1 2.2 1 1 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ28083.1 - 0.00063 19.3 0.1 0.0014 18.1 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Pkinase PF00069.20 OAJ28084.1 - 6.4e-69 231.9 0.0 8.2e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28084.1 - 4.9e-49 166.7 0.0 6.5e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ28084.1 - 8.1e-06 24.9 0.0 5.5e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Apt1 PF10351.4 OAJ28084.1 - 2.9 6.6 8.6 0.42 9.4 3.2 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF4563 PF15124.1 OAJ28085.1 - 0.021 14.3 0.2 2.6 7.6 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4563) DUF4140 PF13600.1 OAJ28085.1 - 1.4 9.4 4.5 4 7.9 0.9 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Bromodomain PF00439.20 OAJ28086.1 - 1.3e-30 105.0 1.8 1.1e-14 54.0 0.1 3.8 3 1 0 3 3 3 2 Bromodomain DUF4600 PF15372.1 OAJ28087.1 - 0.0054 16.9 4.0 0.014 15.6 0.6 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4600) MEDS PF14417.1 OAJ28087.1 - 0.095 11.7 1.8 0.18 10.8 1.3 1.3 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Abhydro_lipase PF04083.11 OAJ28088.1 - 2.5e-14 52.3 0.0 4.7e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 OAJ28088.1 - 6.9e-06 25.8 0.0 9.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ28088.1 - 0.014 14.9 0.1 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DinB_2 PF12867.2 OAJ28090.1 - 0.0002 21.7 0.2 0.00041 20.6 0.1 1.4 1 1 0 1 1 1 1 DinB superfamily MDMPI_N PF11716.3 OAJ28090.1 - 0.0083 16.5 0.2 0.014 15.8 0.1 1.3 1 0 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain ATP-synt_J PF04911.7 OAJ28091.1 - 5.1e-24 83.4 1.0 7.2e-24 82.9 0.7 1.2 1 0 0 1 1 1 1 ATP synthase j chain DASH_Dad3 PF08656.5 OAJ28092.1 - 2.7e-19 68.6 0.4 3.4e-19 68.3 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Fork_head PF00250.13 OAJ28093.1 - 3.3e-21 75.1 0.1 1.6e-19 69.7 0.0 2.5 1 1 0 1 1 1 1 Fork head domain BAF1_ABF1 PF04684.8 OAJ28093.1 - 0.024 13.5 31.8 0.036 12.9 22.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 OAJ28093.1 - 0.08 11.9 0.4 0.13 11.2 0.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 OAJ28093.1 - 1.9 8.3 4.3 2.6 7.8 0.8 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.9 OAJ28093.1 - 2.1 7.9 8.8 4.9 6.7 6.1 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.2 OAJ28093.1 - 8.5 3.9 6.2 13 3.2 4.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dynein_heavy PF03028.10 OAJ28094.1 - 2.5e-168 561.3 0.0 5.1e-168 560.3 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 OAJ28094.1 - 1.4e-46 158.8 4.8 2.7e-46 157.9 3.3 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 OAJ28094.1 - 3.1e-46 157.0 0.5 3e-45 153.8 0.0 2.5 2 1 0 2 2 2 1 ATP-binding dynein motor region D5 Reo_sigmaC PF04582.7 OAJ28094.1 - 4.7 6.2 12.1 0.67 9.0 0.3 3.5 4 0 0 4 4 4 0 Reovirus sigma C capsid protein IFT46_B_C PF12317.3 OAJ28094.1 - 7.5 5.8 8.0 1.2 8.4 0.1 3.0 3 0 0 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal Sugar_tr PF00083.19 OAJ28095.1 - 2.1e-70 237.5 10.8 2.2e-38 131.9 0.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ28095.1 - 8.1e-19 67.5 38.7 9.6e-19 67.2 22.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_16 PF10294.4 OAJ28096.1 - 3.2e-22 78.8 0.0 4.2e-10 39.3 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase AMP-binding PF00501.23 OAJ28097.1 - 3.3e-72 243.1 0.0 5.1e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme DUF2462 PF09495.5 OAJ28098.1 - 2.1e-15 57.1 7.4 2.1e-15 57.1 5.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) RNR_inhib PF08591.5 OAJ28098.1 - 0.18 12.7 1.8 0.39 11.6 1.3 1.5 1 1 0 1 1 1 0 Ribonucleotide reductase inhibitor MSA-2c PF12238.3 OAJ28098.1 - 0.21 11.2 3.0 0.23 11.0 2.1 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c TauD PF02668.11 OAJ28101.1 - 2.6e-53 181.3 0.4 4.5e-53 180.5 0.0 1.6 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family SUZ-C PF12901.2 OAJ28102.1 - 0.11 12.1 0.5 0.29 10.8 0.3 1.6 1 0 0 1 1 1 0 SUZ-C motif Sigma70_ner PF04546.8 OAJ28102.1 - 0.14 11.7 1.6 0.17 11.5 0.8 1.4 1 1 1 2 2 2 0 Sigma-70, non-essential region RhoGAP PF00620.22 OAJ28103.1 - 3.3e-45 153.4 0.0 1.2e-44 151.5 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 OAJ28103.1 - 5.2e-12 45.6 16.0 3.8e-08 33.2 4.9 3.4 3 1 0 3 3 3 2 LIM domain C1_1 PF00130.17 OAJ28103.1 - 2e-05 24.2 7.2 2e-05 24.2 5.0 3.4 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Serglycin PF04360.7 OAJ28103.1 - 0.018 14.7 0.2 0.018 14.7 0.2 6.8 5 2 0 6 6 6 0 Serglycin DUF2559 PF10832.3 OAJ28103.1 - 0.029 14.1 0.1 0.085 12.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) PGA2 PF07543.7 OAJ28103.1 - 0.058 13.1 6.3 0.25 11.1 4.3 2.1 1 0 0 1 1 1 0 Protein trafficking PGA2 Nup88 PF10168.4 OAJ28103.1 - 0.25 9.1 6.8 0.47 8.2 4.7 1.3 1 0 0 1 1 1 0 Nuclear pore component KH_1 PF00013.24 OAJ28104.1 - 2.3e-29 100.7 1.2 1.2e-09 37.6 0.0 5.8 6 0 0 6 6 6 4 KH domain KH_3 PF13014.1 OAJ28104.1 - 1.6e-21 75.5 1.5 4.2e-07 29.4 0.1 5.1 5 0 0 5 5 5 4 KH domain HATPase_c_5 PF14501.1 OAJ28104.1 - 0.19 11.4 0.0 0.63 9.7 0.0 1.8 1 0 0 1 1 1 0 GHKL domain TENA_THI-4 PF03070.11 OAJ28105.1 - 3.9e-08 33.2 0.0 5.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family UQ_con PF00179.21 OAJ28106.1 - 1.9e-12 46.8 0.0 2.5e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Phage_integrase PF00589.17 OAJ28107.1 - 0.00047 19.8 0.0 0.00083 19.0 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family NST1 PF13945.1 OAJ28108.1 - 9.5e-50 169.3 0.0 9.5e-50 169.3 0.0 8.9 7 2 2 9 9 9 2 Salt tolerance down-regulator TFIIA PF03153.8 OAJ28108.1 - 0.0001 22.3 23.3 0.0001 22.3 16.2 9.2 4 2 4 8 8 8 2 Transcription factor IIA, alpha/beta subunit Nsp1_C PF05064.8 OAJ28109.1 - 1.1e-20 73.4 0.0 3.2e-20 71.9 0.0 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region PLDc_2 PF13091.1 OAJ28110.1 - 5.8e-17 61.6 0.0 1.3e-07 31.3 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.17 OAJ28110.1 - 3.4e-15 55.2 0.6 1.1e-06 28.1 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 OAJ28110.1 - 0.071 12.0 1.3 0.28 10.1 0.0 2.3 3 0 0 3 3 3 0 Archaeal transcriptional regulator TrmB MULE PF10551.4 OAJ28111.1 - 7e-20 70.9 0.0 1.5e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.10 OAJ28111.1 - 4.6e-12 45.3 0.3 1.1e-11 44.1 0.2 1.6 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.13 OAJ28111.1 - 1.1e-08 34.0 0.0 2.1e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family zf-CCHC PF00098.18 OAJ28111.1 - 0.00038 20.2 1.3 0.0014 18.4 0.9 2.0 1 0 0 1 1 1 1 Zinc knuckle AFT PF08731.6 OAJ28111.1 - 0.002 18.3 0.2 0.0048 17.0 0.2 1.6 1 0 0 1 1 1 1 Transcription factor AFT SWIM PF04434.12 OAJ28111.1 - 0.0039 16.6 5.3 0.027 13.9 0.7 2.7 2 0 0 2 2 2 1 SWIM zinc finger DUF1059 PF06348.6 OAJ28111.1 - 0.0054 16.5 0.2 0.091 12.5 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1059) Gly-rich_Ago1 PF12764.2 OAJ28113.1 - 0.0019 18.8 1.3 0.0022 18.5 0.9 1.2 1 0 0 1 1 1 1 Glycine-rich region of argonaut Kdo_hydroxy PF11004.3 OAJ28113.1 - 0.022 13.7 0.0 0.026 13.5 0.0 1.0 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase NEMO PF11577.3 OAJ28113.1 - 0.082 12.6 0.6 0.13 12.0 0.4 1.3 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO DUF2702 PF10863.3 OAJ28113.1 - 0.11 12.1 0.3 0.15 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2702) Pyridoxal_deC PF00282.14 OAJ28114.1 - 7.1e-104 347.2 0.0 2.8e-102 341.9 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 OAJ28114.1 - 0.0014 17.7 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 OAJ28114.1 - 0.02 13.8 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_5 PF00266.14 OAJ28114.1 - 0.072 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V AMP-binding PF00501.23 OAJ28115.1 - 8.7e-230 762.2 0.0 3.7e-81 272.6 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 OAJ28115.1 - 2.4e-100 335.3 0.8 1.3e-26 93.1 0.1 4.5 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 OAJ28115.1 - 8.2e-37 125.2 2.2 3.3e-08 33.6 0.0 5.0 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 OAJ28115.1 - 2.2e-11 44.5 0.7 0.0017 19.2 0.0 4.4 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 OAJ28115.1 - 0.035 14.4 1.5 9.9 6.5 0.0 3.3 3 0 0 3 3 3 0 HxxPF-repeated domain Transferase PF02458.10 OAJ28115.1 - 0.038 12.4 0.0 0.41 9.0 0.0 2.5 3 0 0 3 3 3 0 Transferase family Shugoshin_N PF07558.6 OAJ28116.1 - 0.023 14.4 0.4 0.023 14.4 0.3 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region MamL-1 PF09596.5 OAJ28116.1 - 0.025 14.3 3.8 0.073 12.8 2.6 1.8 1 0 0 1 1 1 0 MamL-1 domain Glyco_transf_28 PF03033.15 OAJ28116.1 - 0.052 13.3 0.1 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain DUF972 PF06156.8 OAJ28116.1 - 0.35 11.2 17.5 2.6 8.4 0.0 4.7 3 1 1 4 4 4 0 Protein of unknown function (DUF972) DUF904 PF06005.7 OAJ28116.1 - 0.62 10.3 25.9 0.16 12.3 0.5 4.7 3 1 0 3 3 3 0 Protein of unknown function (DUF904) Tom37_C PF11801.3 OAJ28120.1 - 0.13 12.1 2.5 2 8.2 1.7 2.1 2 0 0 2 2 2 0 Tom37 C-terminal domain DUF4355 PF14265.1 OAJ28120.1 - 0.23 11.3 9.8 0.56 10.1 6.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) RVT_2 PF07727.9 OAJ28121.1 - 3.2e-85 285.0 0.0 4.5e-85 284.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ28121.1 - 1.9e-21 76.3 0.0 3.4e-20 72.3 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ28121.1 - 2.5e-05 23.8 0.0 6.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 OAJ28122.1 - 1.2e-09 37.9 0.0 2.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAJ28122.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ28122.1 - 0.12 12.3 3.6 0.21 11.5 2.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Peroxin-13_N PF04088.8 OAJ28123.1 - 4.2e-46 156.7 0.0 6.6e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 OAJ28123.1 - 2.9e-12 45.8 0.0 5.5e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ28123.1 - 3.2e-12 45.6 0.0 6.3e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ28123.1 - 2e-11 43.3 0.0 3.2e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain RRM_1 PF00076.17 OAJ28124.1 - 8.3e-17 60.5 0.0 1.6e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ28124.1 - 4.6e-13 48.9 0.0 7.4e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ28124.1 - 1.4e-09 37.6 0.0 2.6e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 OAJ28124.1 - 0.049 13.3 0.2 14 5.4 0.0 2.7 2 1 0 2 2 2 0 Limkain b1 Dendrin PF15498.1 OAJ28124.1 - 0.67 8.3 10.5 0.95 7.8 7.3 1.2 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin DNA_pol_phi PF04931.8 OAJ28124.1 - 6.6 4.3 9.8 10 3.7 6.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Mito_carr PF00153.22 OAJ28125.1 - 8.7e-70 230.5 3.6 1.7e-23 82.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.17 OAJ28126.1 - 1.6e-45 154.4 0.0 1.9e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ28126.1 - 3.3e-13 50.1 0.0 4.3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ28126.1 - 3.2e-07 29.7 0.0 4.1e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ28126.1 - 0.00019 20.9 0.0 0.00065 19.1 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 OAJ28126.1 - 0.00044 19.4 0.0 0.00047 19.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Glutaredoxin PF00462.19 OAJ28126.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin ATP_bind_1 PF03029.12 OAJ28126.1 - 0.037 13.5 0.1 0.57 9.6 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 OAJ28126.1 - 0.04 13.8 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 OAJ28126.1 - 0.045 13.6 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 OAJ28126.1 - 0.056 12.7 0.0 0.15 11.3 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B UAA PF08449.6 OAJ28128.1 - 3.6e-72 242.8 3.6 6.1e-53 179.7 0.0 2.1 2 0 0 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.10 OAJ28128.1 - 0.0003 19.9 0.1 0.00057 19.0 0.1 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter CBM_20 PF00686.14 OAJ28129.1 - 0.018 14.6 0.1 0.058 12.9 0.1 1.9 1 0 0 1 1 1 0 Starch binding domain COX15-CtaA PF02628.10 OAJ28129.1 - 0.68 8.7 3.7 15 4.3 0.0 2.4 2 1 0 2 2 2 0 Cytochrome oxidase assembly protein Glt_symporter PF03616.9 OAJ28129.1 - 3.8 5.9 5.5 5.5 5.3 0.0 3.0 3 0 0 3 3 3 0 Sodium/glutamate symporter NUDIX_2 PF13869.1 OAJ28130.1 - 2.1e-80 268.4 0.0 2.4e-80 268.2 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase ATP-synt_C PF00137.16 OAJ28131.1 - 9e-28 95.9 31.7 4.6e-16 58.4 7.3 3.0 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.19 OAJ28131.1 - 4.3 6.9 11.0 0.18 11.4 1.1 3.0 1 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L NAD_binding_2 PF03446.10 OAJ28135.1 - 3.5e-47 160.2 0.1 3.9e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 OAJ28135.1 - 0.0012 19.2 0.1 0.0018 18.6 0.1 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 OAJ28135.1 - 0.043 13.9 0.2 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase DRTGG PF07085.7 OAJ28135.1 - 0.13 11.8 0.0 0.32 10.6 0.0 1.7 1 1 0 1 1 1 0 DRTGG domain 2-Hacid_dh_C PF02826.14 OAJ28135.1 - 0.15 11.2 0.1 0.39 9.8 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YL1_C PF08265.6 OAJ28138.1 - 6.2e-10 38.4 1.4 1.1e-09 37.6 1.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Bac_luciferase PF00296.15 OAJ28139.1 - 2 7.4 9.3 1.4 7.9 2.9 2.0 2 0 0 2 2 2 0 Luciferase-like monooxygenase FAD_binding_3 PF01494.14 OAJ28141.1 - 0.0054 15.8 0.0 0.0071 15.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain eIF-1a PF01176.14 OAJ28142.1 - 5.8e-28 96.1 0.1 8.2e-28 95.6 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ATG_C PF09333.6 OAJ28143.1 - 3.8e-26 91.0 0.5 1.2e-25 89.5 0.1 2.0 2 0 0 2 2 2 1 ATG C terminal domain Fib_alpha PF08702.5 OAJ28143.1 - 0.0028 17.8 0.2 0.0053 16.8 0.1 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DPM3 PF08285.6 OAJ28144.1 - 6.1e-27 93.2 0.0 6.8e-27 93.1 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) HhH-GPD PF00730.20 OAJ28145.1 - 5e-10 39.6 0.0 1.1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein AA_permease PF00324.16 OAJ28146.1 - 1.4e-117 392.9 37.7 1.6e-117 392.8 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAJ28146.1 - 4.4e-35 121.0 43.6 5.5e-35 120.7 30.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 OAJ28146.1 - 0.061 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) tRNA-synt_2b PF00587.20 OAJ28149.1 - 7.9e-17 61.3 0.0 7.5e-16 58.1 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) AATF-Che1 PF13339.1 OAJ28149.1 - 0.16 12.1 0.8 0.36 10.9 0.6 1.6 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor PTR2 PF00854.16 OAJ28150.1 - 4.3e-40 137.6 14.8 3.6e-23 81.9 4.7 2.3 2 0 0 2 2 2 2 POT family WD40 PF00400.27 OAJ28151.1 - 1.8e-17 62.4 5.0 4.2e-06 26.4 0.0 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat Catalase PF00199.14 OAJ28152.1 - 1.5e-177 590.0 1.2 1.8e-177 589.8 0.8 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 OAJ28152.1 - 3.1e-20 71.8 0.0 7.1e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive HLH PF00010.21 OAJ28153.1 - 1.5e-07 31.0 0.3 2.6e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nucleoplasmin PF03066.10 OAJ28153.1 - 0.0061 16.0 3.3 0.0093 15.4 2.3 1.3 1 0 0 1 1 1 1 Nucleoplasmin Daxx PF03344.10 OAJ28153.1 - 0.035 12.6 7.2 0.082 11.3 5.0 1.6 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 OAJ28153.1 - 0.063 12.3 8.4 0.11 11.5 5.8 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 OAJ28153.1 - 0.074 10.9 7.4 0.14 10.0 5.1 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 OAJ28153.1 - 0.12 10.4 2.8 0.21 9.5 1.9 1.5 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 OAJ28153.1 - 0.25 10.2 1.7 0.39 9.6 1.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.4 OAJ28153.1 - 1 8.0 17.1 8.1 5.0 11.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 OAJ28153.1 - 1.1 9.6 11.9 3.8 7.8 8.3 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.11 OAJ28154.1 - 4.4e-41 140.7 20.7 4.4e-41 140.7 14.4 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF1183 PF06682.7 OAJ28155.1 - 3.6e-51 174.6 27.3 1e-49 169.9 18.9 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) TPR_12 PF13424.1 OAJ28157.1 - 2.4e-64 213.2 88.9 1.8e-10 40.6 0.3 14.3 5 3 13 18 18 18 16 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ28157.1 - 4.3e-58 191.7 103.3 9.8e-06 25.3 0.3 21.7 23 0 0 23 23 23 16 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ28157.1 - 2.2e-14 52.1 53.4 1.1 9.3 0.1 19.4 22 0 0 22 22 21 5 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ28157.1 - 1.4e-08 33.9 16.8 3.9 7.2 0.0 14.1 17 0 0 17 17 17 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ28157.1 - 6e-07 29.0 57.2 0.046 13.3 0.1 12.0 8 4 7 15 15 15 8 TPR repeat DUF3856 PF12968.2 OAJ28157.1 - 3.7e-06 26.8 41.8 0.13 12.0 0.0 8.9 4 3 3 9 9 9 6 Domain of Unknown Function (DUF3856) Cas_Csm6 PF09659.5 OAJ28157.1 - 3.7e-05 22.5 0.4 13 4.2 0.0 6.0 6 1 2 8 8 8 0 CRISPR-associated protein (Cas_Csm6) TPR_8 PF13181.1 OAJ28157.1 - 0.0017 17.9 19.2 24 4.9 0.0 11.3 13 0 0 13 13 13 0 Tetratricopeptide repeat Transcript_VP30 PF11507.3 OAJ28157.1 - 0.0021 17.8 0.0 17 5.2 0.0 4.6 4 0 0 4 4 4 0 Ebola virus-specific transcription factor VP30 MIT PF04212.13 OAJ28157.1 - 0.015 15.1 9.1 0.026 14.4 0.0 5.8 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 OAJ28157.1 - 0.065 13.3 14.2 0.97 9.6 0.9 6.0 5 0 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 OAJ28157.1 - 0.17 11.1 25.9 0.36 10.1 0.1 9.8 12 0 0 12 12 12 0 SHNi-TPR GTPase_Cys_C PF12631.2 OAJ28157.1 - 6.8 7.1 16.9 3.9 7.9 0.2 6.3 7 1 0 8 8 8 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE TPR_12 PF13424.1 OAJ28158.1 - 0.0087 15.9 0.6 0.056 13.3 0.0 2.6 4 1 0 4 4 4 1 Tetratricopeptide repeat Aminotran_3 PF00202.16 OAJ28159.1 - 2.3e-82 276.5 0.0 2.9e-82 276.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Ets PF00178.17 OAJ28160.1 - 0.079 13.1 0.2 0.36 10.9 0.0 2.2 3 0 0 3 3 3 0 Ets-domain DUF3827 PF12877.2 OAJ28160.1 - 1.4 6.9 6.7 2.1 6.3 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) MS_channel PF00924.13 OAJ28161.1 - 5.8e-24 84.5 0.8 1.1e-23 83.7 0.5 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.1 OAJ28161.1 - 0.025 14.7 0.1 0.069 13.2 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 OAJ28161.1 - 0.037 13.3 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 EF hand Flu_PB2 PF00604.12 OAJ28161.1 - 0.23 9.2 0.0 0.33 8.7 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB2 DUF4328 PF14219.1 OAJ28161.1 - 0.99 8.6 12.7 0.28 10.4 5.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4328) RVT_2 PF07727.9 OAJ28162.1 - 2.1e-75 252.8 0.0 2.9e-75 252.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ28162.1 - 1.2e-17 64.0 0.0 3.5e-17 62.6 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 OAJ28162.1 - 1.7e-11 43.6 0.0 3.6e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ28162.1 - 4.2e-08 32.9 0.0 7.1e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAJ28162.1 - 7.1e-06 25.5 0.0 1.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.1 OAJ28162.1 - 0.00023 20.5 0.1 0.00048 19.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) RVP PF00077.15 OAJ28162.1 - 0.02 14.7 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease rve_3 PF13683.1 OAJ28162.1 - 0.022 14.2 0.0 0.059 12.8 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain zf-CCHC PF00098.18 OAJ28162.1 - 0.027 14.4 4.9 0.068 13.1 3.4 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_3 PF13456.1 OAJ28162.1 - 0.084 12.6 0.0 0.37 10.5 0.0 2.1 1 0 0 1 1 1 0 Reverse transcriptase-like zf-CCHC_2 PF13696.1 OAJ28162.1 - 0.1 12.0 4.1 0.22 11.0 2.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Pkinase_Tyr PF07714.12 OAJ28165.1 - 5.5e-09 35.4 0.0 9e-06 24.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 OAJ28165.1 - 1.6e-08 34.0 0.0 3.1e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.18 OAJ28165.1 - 0.00096 18.9 0.1 0.0024 17.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAJ28165.1 - 0.048 13.2 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase H_lectin PF09458.5 OAJ28166.1 - 1.1e-11 44.1 0.1 5.3e-08 32.4 0.0 2.7 2 0 0 2 2 2 2 H-type lectin domain CR6_interact PF10147.4 OAJ28166.1 - 0.03 13.6 0.4 0.051 12.8 0.3 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Complex1_LYR_1 PF13232.1 OAJ28169.1 - 1.1e-13 51.1 0.0 1.8e-13 50.5 0.0 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 OAJ28169.1 - 9.8e-07 28.4 6.4 2e-06 27.5 4.4 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) GCR1_C PF12550.3 OAJ28170.1 - 2.6e-05 23.9 0.0 6.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_Tnp_1_2 PF13022.1 OAJ28170.1 - 0.027 14.2 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_23 PF13384.1 OAJ28170.1 - 0.029 14.0 0.1 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain Phage_integrase PF00589.17 OAJ28170.1 - 0.12 12.0 0.0 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 Phage integrase family XS PF03468.9 OAJ28171.1 - 0.053 13.4 0.0 0.061 13.2 0.0 1.1 1 0 0 1 1 1 0 XS domain RRM_6 PF14259.1 OAJ28173.1 - 0.00018 21.4 0.0 0.0011 18.8 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ28173.1 - 0.00092 18.8 0.0 0.23 11.1 0.0 3.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 OAJ28173.1 - 0.38 8.6 33.7 0.0066 14.4 8.2 2.0 2 0 0 2 2 2 0 Nop14-like family UPF0052 PF01933.13 OAJ28174.1 - 7.9e-38 130.4 0.0 9.5e-26 90.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family UPF0052 RNB PF00773.14 OAJ28175.1 - 3.3e-89 299.3 0.0 4.4e-89 298.9 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 OAJ28175.1 - 3.1e-07 30.5 0.0 1e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 PIN domain DicB PF05358.6 OAJ28175.1 - 0.12 11.8 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 DicB protein DUF1162 PF06650.7 OAJ28176.1 - 9e-75 251.4 0.1 8.9e-71 238.3 0.0 4.0 3 1 1 4 4 4 3 Protein of unknown function (DUF1162) Chorein_N PF12624.2 OAJ28176.1 - 2.8e-40 136.5 0.4 1e-39 134.7 0.0 2.2 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 OAJ28176.1 - 3.7e-08 33.4 0.2 2.5e-07 30.7 0.0 2.5 2 0 0 2 2 2 1 ATG C terminal domain RRM_1 PF00076.17 OAJ28177.1 - 7.9e-05 22.2 0.0 0.00017 21.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ28177.1 - 0.018 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) N2227 PF07942.7 OAJ28177.1 - 0.15 11.0 0.0 0.29 10.0 0.0 1.4 1 0 0 1 1 1 0 N2227-like protein Pkinase PF00069.20 OAJ28178.1 - 1e-74 250.9 0.0 1.4e-74 250.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28178.1 - 1.3e-41 142.4 0.0 2.1e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 OAJ28178.1 - 5.2e-19 67.9 0.0 3.3e-08 33.3 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 OAJ28178.1 - 5e-09 35.5 0.0 6.6e-08 31.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 OAJ28178.1 - 0.058 12.4 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tbf5 PF06331.7 OAJ28179.1 - 3.7e-23 81.0 0.1 4e-23 80.9 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 FlbD PF06289.6 OAJ28179.1 - 0.072 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Flagellar protein (FlbD) BTB PF00651.26 OAJ28180.1 - 2.1e-14 53.4 0.3 8.2e-10 38.6 0.0 3.5 3 0 0 3 3 3 3 BTB/POZ domain CAP_GLY PF01302.20 OAJ28180.1 - 4e-08 32.8 0.0 2.1e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 CAP-Gly domain Pyr_redox_3 PF13738.1 OAJ28181.1 - 0.07 13.1 0.6 6.6 6.7 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ28181.1 - 0.1 13.0 0.2 1.2 9.6 0.1 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LisH PF08513.6 OAJ28182.1 - 0.00037 20.1 0.0 0.00072 19.2 0.0 1.5 1 0 0 1 1 1 1 LisH AMP-binding PF00501.23 OAJ28184.1 - 6.6e-35 120.3 0.2 1.9e-34 118.8 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 OAJ28184.1 - 4.1e-26 91.4 0.0 7.4e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 OAJ28184.1 - 3.8e-08 33.0 0.0 1.2e-07 31.4 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 OAJ28184.1 - 4.1e-06 26.9 0.0 8.9e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 OAJ28184.1 - 0.0076 14.9 0.0 0.39 9.3 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 OAJ28184.1 - 0.013 15.3 0.4 0.075 12.9 0.1 2.5 2 1 0 2 2 2 0 short chain dehydrogenase zf-4CXXC_R1 PF10497.4 OAJ28184.1 - 0.14 12.3 0.2 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Polysacc_synt_2 PF02719.10 OAJ28184.1 - 0.22 10.4 0.0 5.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein p450 PF00067.17 OAJ28185.1 - 1.1e-78 264.7 0.0 1.3e-78 264.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PspB PF06667.7 OAJ28185.1 - 0.063 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Phage shock protein B Co_AT_N PF12557.3 OAJ28185.1 - 0.064 13.1 0.2 0.15 12.0 0.2 1.6 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal ketoacyl-synt PF00109.21 OAJ28186.1 - 1.3e-76 257.5 0.0 3.9e-76 255.8 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 OAJ28186.1 - 6.7e-47 160.3 0.0 1.4e-43 149.4 0.0 3.7 3 1 1 4 4 4 2 Acyl transferase domain Ketoacyl-synt_C PF02801.17 OAJ28186.1 - 4.7e-33 113.5 0.9 1e-32 112.5 0.6 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 OAJ28186.1 - 1.2e-27 96.8 0.0 2.4e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 OAJ28186.1 - 8.3e-27 94.8 0.1 8.5e-26 91.5 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 OAJ28186.1 - 4.4e-15 55.6 3.1 1.1e-06 28.7 0.2 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 OAJ28186.1 - 9.9e-11 41.9 2.3 6.5e-09 36.0 0.0 3.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ28186.1 - 2.5e-09 37.0 0.3 0.00012 21.8 0.0 3.9 4 0 0 4 4 4 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 OAJ28186.1 - 2.7e-05 23.2 0.1 8.2e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_1 PF00561.15 OAJ28186.1 - 0.056 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold p450 PF00067.17 OAJ28187.1 - 1.8e-05 23.4 0.0 1.8e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sporozoite_P67 PF05642.6 OAJ28188.1 - 0.2 9.5 21.3 0.23 9.2 14.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen D123 PF07065.9 OAJ28188.1 - 2.2 7.2 12.6 2.4 7.1 8.8 1.1 1 0 0 1 1 1 0 D123 POX PF07526.6 OAJ28188.1 - 3 8.0 11.2 3.6 7.8 7.8 1.2 1 0 0 1 1 1 0 Associated with HOX Endonuc_Holl PF10107.4 OAJ28188.1 - 8.5 6.0 9.5 9.5 5.8 6.6 1.0 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF3381 PF11861.3 OAJ28188.1 - 9.1 5.7 27.0 10 5.5 18.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) YqfQ PF14181.1 OAJ28188.1 - 9.8 6.1 19.3 11 6.0 13.4 1.1 1 0 0 1 1 1 0 YqfQ-like protein Fasciclin PF02469.17 OAJ28189.1 - 3e-11 43.4 0.0 4.1e-08 33.2 0.0 2.7 2 1 0 2 2 2 2 Fasciclin domain Xpo1 PF08389.7 OAJ28190.1 - 0.0027 17.6 0.1 0.011 15.6 0.0 2.0 2 1 0 2 2 2 1 Exportin 1-like protein FAT PF02259.18 OAJ28191.1 - 3.3e-66 223.6 2.0 3.3e-66 223.6 1.4 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 OAJ28191.1 - 1.7e-23 83.3 0.0 5.1e-23 81.7 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 OAJ28191.1 - 0.013 14.9 0.5 0.033 13.6 0.3 1.7 1 0 0 1 1 1 0 FATC domain AAA_5 PF07728.9 OAJ28193.1 - 9.8e-37 125.7 0.0 7.1e-29 100.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) NTR2 PF15458.1 OAJ28195.1 - 0.019 14.2 0.3 0.023 13.9 0.2 1.1 1 0 0 1 1 1 0 Nineteen complex-related protein 2 SPT2 PF08243.6 OAJ28195.1 - 0.15 12.3 1.4 0.18 12.1 1.0 1.5 1 1 0 1 1 1 0 SPT2 chromatin protein Pkinase PF00069.20 OAJ28196.1 - 3.3e-45 154.2 0.0 6.1e-45 153.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28196.1 - 1.3e-17 63.7 0.0 1.9e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ28196.1 - 0.0012 17.8 0.0 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 OAJ28196.1 - 0.0033 16.7 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family DUF294_C PF10335.4 OAJ28196.1 - 0.069 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain Choline_kinase PF01633.15 OAJ28196.1 - 0.18 11.3 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Transket_pyr PF02779.19 OAJ28197.1 - 9.2e-61 204.4 0.0 1.5e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 OAJ28197.1 - 4.7e-43 147.0 0.0 1.5e-42 145.3 0.0 1.7 2 0 0 2 2 2 1 Dehydrogenase E1 component PQ-loop PF04193.9 OAJ28198.1 - 6.6e-14 51.1 0.2 1.8e-12 46.5 0.1 2.6 2 0 0 2 2 2 1 PQ loop repeat Amidinotransf PF02274.12 OAJ28199.1 - 1.2e-21 77.0 0.0 5e-21 75.0 0.0 1.7 1 1 0 1 1 1 1 Amidinotransferase MMtag PF10159.4 OAJ28200.1 - 2e-31 107.8 3.0 2e-31 107.8 2.1 3.5 2 1 1 3 3 3 1 Kinase phosphorylation protein DUF4042 PF13251.1 OAJ28201.1 - 5.3e-09 35.8 3.6 3e-08 33.3 0.1 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.1 OAJ28201.1 - 7.9e-07 29.2 35.7 0.19 12.0 2.3 6.6 3 2 3 6 6 6 5 HEAT repeats HEAT PF02985.17 OAJ28201.1 - 6.8e-06 25.7 24.8 0.98 9.6 0.2 8.5 8 0 0 8 8 8 4 HEAT repeat Cyto_heme_lyase PF01265.12 OAJ28202.1 - 2.5e-63 214.0 0.0 3.3e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Clat_adaptor_s PF01217.15 OAJ28203.1 - 1.2e-43 148.2 0.3 4.2e-34 117.3 0.2 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain MAGE_N PF12440.3 OAJ28203.1 - 0.13 12.5 2.8 1.6 9.0 0.3 2.2 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Herpes_capsid PF06112.6 OAJ28203.1 - 3 7.8 11.3 1.3 9.0 1.1 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein YfhE PF14152.1 OAJ28204.1 - 0.15 11.9 0.7 0.3 11.0 0.5 1.4 1 0 0 1 1 1 0 YfhE-like protein Fungal_trans_2 PF11951.3 OAJ28204.1 - 0.19 10.3 1.2 0.41 9.1 0.9 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain Pex14_N PF04695.8 OAJ28204.1 - 2.9 7.9 7.4 0.35 10.9 0.5 2.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_S7e PF01251.13 OAJ28205.1 - 1.9e-79 265.6 0.1 2.3e-79 265.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e Thr_synth_N PF14821.1 OAJ28206.1 - 6.8e-27 93.3 0.0 2.3e-26 91.5 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 OAJ28206.1 - 1.4e-21 77.0 0.0 3.1e-20 72.6 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme WD40 PF00400.27 OAJ28208.1 - 2.9e-38 128.3 10.4 1.5e-08 34.2 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 OAJ28208.1 - 3.7e-30 103.6 0.1 7.8e-30 102.6 0.1 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Apc4_WD40 PF12894.2 OAJ28208.1 - 0.0015 17.9 0.1 1.1 8.7 0.0 3.8 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Rad51 PF08423.6 OAJ28209.1 - 3.6e-138 458.6 0.1 4.4e-138 458.3 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 OAJ28209.1 - 1.7e-15 56.9 0.0 2.5e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 OAJ28209.1 - 7.4e-09 35.0 0.1 1e-08 34.6 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 OAJ28209.1 - 2.5e-08 33.9 0.0 5.3e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 OAJ28209.1 - 5.5e-08 32.1 0.0 8.8e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 KaiC PAXNEB PF05625.6 OAJ28209.1 - 0.01 14.7 0.7 0.026 13.3 0.3 1.7 1 1 1 2 2 2 0 PAXNEB protein HHH PF00633.18 OAJ28209.1 - 0.012 15.2 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif AAA_22 PF13401.1 OAJ28209.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.10 OAJ28209.1 - 0.15 10.9 0.1 0.32 9.8 0.0 1.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Fungal_trans PF04082.13 OAJ28210.1 - 6.3e-06 25.2 0.1 1.1e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ28210.1 - 0.0047 16.8 14.8 0.0076 16.1 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fasciclin PF02469.17 OAJ28211.1 - 5.7e-39 133.0 0.0 3.1e-08 33.6 0.0 6.5 5 2 0 5 5 5 5 Fasciclin domain Aminotran_1_2 PF00155.16 OAJ28212.1 - 2e-40 138.8 0.0 3.6e-40 138.0 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 OAJ28212.1 - 0.00046 18.5 0.0 0.00096 17.5 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PfkB PF00294.19 OAJ28213.1 - 0.00035 19.7 0.9 0.006 15.7 0.3 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase UBX PF00789.15 OAJ28214.1 - 3.3e-05 23.8 0.0 0.00013 21.9 0.0 2.0 2 0 0 2 2 2 1 UBX domain UBA PF00627.26 OAJ28214.1 - 0.0053 16.5 0.1 0.24 11.3 0.0 3.2 3 0 0 3 3 3 1 UBA/TS-N domain zf-C2H2 PF00096.21 OAJ28214.1 - 0.073 13.4 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zinc_ribbon_4 PF13717.1 OAJ28214.1 - 0.098 12.3 0.1 0.28 10.8 0.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain Rtf2 PF04641.7 OAJ28214.1 - 0.11 11.7 20.9 0.18 10.9 14.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zinc_ribbon_5 PF13719.1 OAJ28214.1 - 0.11 12.0 0.4 0.31 10.6 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain DUF572 PF04502.8 OAJ28214.1 - 0.13 11.4 22.8 0.18 11.0 15.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Asp-B-Hydro_N PF05279.6 OAJ28214.1 - 1.4 8.6 23.0 2.1 8.1 16.0 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PLRV_ORF5 PF01690.12 OAJ28214.1 - 1.8 7.6 11.0 2.2 7.3 7.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein zf-C2H2_2 PF12756.2 OAJ28214.1 - 2.1 8.4 7.0 0.3 11.1 0.2 2.4 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Peptidase_S49_N PF08496.5 OAJ28214.1 - 3.8 7.2 20.1 0.43 10.3 4.6 2.2 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Hex_IIIa PF02455.11 OAJ28214.1 - 4 6.0 8.9 5.8 5.4 6.1 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Lipoprotein_X PF03305.8 OAJ28214.1 - 9.7 5.4 9.3 15 4.8 6.5 1.2 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein SKN1 PF03935.10 OAJ28215.1 - 3.7e-174 579.5 2.7 4.3e-174 579.3 1.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) BAR_2 PF10455.4 OAJ28216.1 - 1.2e-41 142.5 0.0 3.6e-41 140.9 0.0 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 OAJ28216.1 - 8.4e-13 48.3 0.5 1.5e-10 41.0 0.1 2.1 2 0 0 2 2 2 2 BAR domain ATG16 PF08614.6 OAJ28216.1 - 0.0048 16.7 1.9 0.27 11.0 0.6 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Phycobilisome PF00502.14 OAJ28216.1 - 0.069 12.9 1.0 2.3 7.9 0.0 2.5 1 1 0 2 2 2 0 Phycobilisome protein Uds1 PF15456.1 OAJ28216.1 - 0.37 10.7 7.8 0.89 9.5 0.1 2.9 2 1 1 3 3 3 0 Up-regulated During Septation Seryl_tRNA_N PF02403.17 OAJ28216.1 - 0.51 10.3 0.0 0.51 10.3 0.0 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1090 PF06476.7 OAJ28216.1 - 3 7.5 9.0 0.22 11.1 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) Met_10 PF02475.11 OAJ28217.1 - 1.2e-49 168.6 0.0 6.2e-40 136.9 0.0 2.3 2 0 0 2 2 2 2 Met-10+ like-protein PhoD PF09423.5 OAJ28218.1 - 0.00049 18.8 0.0 0.019 13.5 0.1 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Dehydrin PF00257.14 OAJ28218.1 - 0.014 15.6 0.3 0.03 14.6 0.2 1.5 1 0 0 1 1 1 0 Dehydrin DUF3366 PF11846.3 OAJ28219.1 - 0.056 13.3 3.4 0.11 12.3 0.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3366) F-box PF00646.28 OAJ28220.1 - 2.3e-07 30.2 0.1 3.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ28220.1 - 0.00021 20.9 0.1 0.00043 19.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like PBD PF00786.23 OAJ28221.1 - 6.5e-05 23.2 0.0 0.00031 21.0 0.0 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain eIF-3c_N PF05470.7 OAJ28222.1 - 0.2 9.6 3.3 0.26 9.3 2.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus HTH_Tnp_IS630 PF01710.11 OAJ28223.1 - 0.02 14.5 0.3 0.052 13.2 0.2 1.7 1 0 0 1 1 1 0 Transposase N-glycanase_N PF09112.5 OAJ28223.1 - 0.044 13.1 0.3 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Peptide-N-glycosidase F, N terminal TFR_dimer PF04253.10 OAJ28223.1 - 0.16 11.5 1.1 0.31 10.5 0.0 2.0 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain RVT_1 PF00078.22 OAJ28225.1 - 9.7e-23 80.6 0.0 1.7e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ28225.1 - 0.0034 16.9 0.0 0.0075 15.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase AA_permease PF00324.16 OAJ28226.1 - 2.2e-132 441.7 48.4 2.7e-132 441.5 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAJ28226.1 - 1.2e-38 132.7 51.3 1.5e-38 132.5 35.5 1.1 1 0 0 1 1 1 1 Amino acid permease DnaJ PF00226.26 OAJ28227.1 - 6.8e-23 80.1 0.6 1.1e-22 79.4 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 OAJ28227.1 - 3.7e-21 74.7 0.2 1.5e-19 69.6 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 OAJ28227.1 - 2.1e-14 53.2 19.2 3.5e-14 52.6 13.3 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 OAJ28227.1 - 0.22 11.2 12.0 0.57 9.8 2.6 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Stc1 PF12898.2 OAJ28227.1 - 1.1 9.3 7.8 9.1 6.4 0.4 2.3 2 0 0 2 2 2 0 Stc1 domain PS_Dcarbxylase PF02666.10 OAJ28228.1 - 4.8e-76 254.5 0.0 6.2e-74 247.6 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.6 OAJ28228.1 - 0.0029 17.1 0.0 0.0081 15.7 0.0 1.7 1 0 0 1 1 1 1 MNLL subunit DUF3309 PF11752.3 OAJ28228.1 - 0.14 11.9 0.8 2.4 7.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) DUF427 PF04248.7 OAJ28230.1 - 5e-28 96.6 0.9 9.1e-27 92.5 0.1 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF427) Sdh_cyt PF01127.17 OAJ28231.1 - 0.00036 20.3 1.9 0.0032 17.3 0.2 2.6 2 1 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1691 PF07950.6 OAJ28231.1 - 0.0013 18.6 1.5 0.0013 18.6 1.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1691) zf-C3Hc3H PF13891.1 OAJ28232.1 - 1.3 9.1 6.4 1.5 8.9 2.1 2.1 2 0 0 2 2 2 0 Potential DNA-binding domain Yip1 PF04893.12 OAJ28233.1 - 3.3e-09 36.4 11.5 3.3e-09 36.4 8.0 1.5 2 0 0 2 2 2 1 Yip1 domain LCM PF04072.9 OAJ28234.1 - 3.6e-16 59.2 0.0 2.2e-15 56.7 0.0 2.1 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase NT-C2 PF10358.4 OAJ28235.1 - 9.8e-12 44.5 0.0 1.9e-05 24.1 0.0 3.1 2 1 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins Nucleoplasmin PF03066.10 OAJ28235.1 - 7 6.1 11.4 19 4.7 7.9 1.7 1 0 0 1 1 1 0 Nucleoplasmin UBA PF00627.26 OAJ28236.1 - 0.0023 17.7 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain TFIIA PF03153.8 OAJ28238.1 - 0.79 9.5 10.9 0.94 9.3 7.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 OAJ28238.1 - 4.2 6.6 26.8 5.6 6.2 18.6 1.1 1 0 0 1 1 1 0 Vta1 like Chitin_synth_2 PF03142.10 OAJ28239.1 - 1.9e-243 808.6 0.0 2.5e-243 808.2 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 OAJ28239.1 - 8.4e-108 361.2 0.0 1.4e-107 360.4 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 OAJ28239.1 - 5.4e-18 65.4 3.0 5.4e-18 65.4 2.1 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ28239.1 - 6.5e-18 65.3 0.0 5.9e-15 55.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 OAJ28239.1 - 1.3e-16 60.1 0.1 1.5e-11 43.9 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 OAJ28239.1 - 2.7e-13 49.4 0.0 2.2e-11 43.3 0.0 2.6 2 0 0 2 2 2 1 DEK C terminal domain Glycos_transf_2 PF00535.21 OAJ28239.1 - 2e-09 37.3 0.0 7.8e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 OAJ28239.1 - 7.3e-07 28.6 0.0 1.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Pkinase PF00069.20 OAJ28241.1 - 5.5e-23 81.4 0.0 7.4e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28241.1 - 3e-17 62.5 0.0 3.7e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SDH_beta PF03315.10 OAJ28241.1 - 0.52 10.3 3.7 0.93 9.5 2.6 1.5 1 1 0 1 1 1 0 Serine dehydratase beta chain Transposase_21 PF02992.9 OAJ28242.1 - 5.8e-21 74.6 0.0 8.8e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ28242.1 - 0.00048 19.5 0.0 0.00084 18.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Barstar PF01337.13 OAJ28244.1 - 0.011 15.5 2.0 0.047 13.5 0.0 3.0 3 2 2 5 5 5 0 Barstar (barnase inhibitor) DUF4574 PF15141.1 OAJ28244.1 - 0.16 11.7 6.0 0.3 10.8 3.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4574) Phage_Gp23 PF10669.4 OAJ28244.1 - 3.2 7.8 17.8 2.7 8.1 2.0 2.6 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Histone PF00125.19 OAJ28246.1 - 1.2e-29 102.2 0.5 2e-29 101.4 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ28246.1 - 1.8e-05 24.8 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAJ28246.1 - 0.0026 17.7 0.2 0.0043 17.0 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 OAJ28246.1 - 0.0039 16.4 0.1 0.005 16.1 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T MCPVI PF02993.9 OAJ28247.1 - 5.7 7.0 7.5 0.9 9.6 2.5 1.6 2 0 0 2 2 2 0 Minor capsid protein VI DUF2360 PF10152.4 OAJ28248.1 - 0.038 14.2 3.2 0.08 13.2 2.2 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Transglut_core3 PF13471.1 OAJ28250.1 - 0.017 14.8 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 Transglutaminase-like superfamily BCL9 PF11502.3 OAJ28250.1 - 0.025 14.0 0.1 0.047 13.2 0.1 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein DUF2746 PF10874.3 OAJ28250.1 - 0.092 12.9 1.4 0.15 12.2 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2746) Syntaxin PF00804.20 OAJ28250.1 - 0.2 11.8 1.1 0.26 11.4 0.8 1.2 1 0 0 1 1 1 0 Syntaxin Methyltransf_11 PF08241.7 OAJ28251.1 - 2.7e-18 66.2 0.0 1.1e-17 64.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ28251.1 - 1.4e-15 57.1 0.0 2.1e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ28251.1 - 6e-12 46.1 0.0 1.3e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ28251.1 - 4.2e-11 43.1 0.0 1.2e-10 41.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ28251.1 - 1.1e-10 41.7 0.0 2.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ28251.1 - 1.2e-10 40.9 0.0 1.8e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 OAJ28251.1 - 1.9e-10 40.6 0.0 3.1e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ28251.1 - 6.6e-10 39.0 0.1 2.8e-09 37.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 OAJ28251.1 - 3.3e-05 23.3 0.0 0.00011 21.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 OAJ28251.1 - 0.00012 21.1 0.0 0.00037 19.5 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.11 OAJ28251.1 - 0.00014 20.4 0.0 0.00018 20.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPMT PF05724.6 OAJ28251.1 - 0.0002 20.8 0.0 0.0009 18.7 0.0 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.15 OAJ28251.1 - 0.0051 15.9 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 OAJ28251.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 OAJ28251.1 - 0.015 14.3 0.0 0.039 12.9 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.5 OAJ28251.1 - 0.023 14.2 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_8 PF05148.10 OAJ28251.1 - 0.13 11.9 0.0 3.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase PrmA PF06325.8 OAJ28251.1 - 0.19 10.7 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Lung_7-TM_R PF06814.8 OAJ28253.1 - 5e-52 176.6 19.0 8.2e-52 175.9 13.1 1.3 1 1 0 1 1 1 1 Lung seven transmembrane receptor YlaC PF10777.4 OAJ28253.1 - 0.028 13.9 7.5 0.29 10.6 2.1 2.4 2 0 0 2 2 2 0 Inner membrane protein YlaC S1 PF00575.18 OAJ28254.1 - 2.7e-37 126.6 7.1 2.8e-07 30.5 0.4 8.0 9 0 0 9 9 9 5 S1 RNA binding domain TPR_16 PF13432.1 OAJ28254.1 - 2.1e-09 37.7 1.3 0.00063 20.3 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat Suf PF05843.9 OAJ28254.1 - 2.3e-06 27.5 11.6 0.00015 21.6 0.0 3.7 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.1 OAJ28254.1 - 3.2e-06 27.3 0.0 1.8 8.9 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.5 OAJ28254.1 - 0.00012 21.0 3.8 0.011 14.6 0.8 3.2 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 OAJ28254.1 - 0.00039 20.8 1.1 3.9 8.3 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 OAJ28254.1 - 0.00061 18.9 1.8 0.0025 16.9 1.2 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TFIIA PF03153.8 OAJ28254.1 - 0.0038 17.1 13.5 0.0038 17.1 9.4 4.0 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit TPR_6 PF13174.1 OAJ28254.1 - 0.011 16.1 0.3 3.8 8.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Nop14 PF04147.7 OAJ28254.1 - 0.19 9.5 58.7 0.02 12.8 1.0 3.5 3 0 0 3 3 3 0 Nop14-like family NUDIX PF00293.23 OAJ28255.1 - 3.9e-13 49.2 0.0 6.9e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Collagen PF01391.13 OAJ28257.1 - 3.1e-13 49.0 81.1 0.00015 21.2 13.2 3.8 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) GCD14 PF08704.5 OAJ28258.1 - 4.2e-72 242.5 5.3 6.7e-30 104.3 0.1 4.2 3 1 0 4 4 4 4 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 OAJ28258.1 - 0.0016 18.0 0.0 0.0038 16.7 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 OAJ28258.1 - 0.0028 17.6 0.1 0.0072 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 OAJ28258.1 - 0.045 12.7 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 OAJ28258.1 - 0.1 13.1 0.0 1.5 9.4 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ28258.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Nop14 PF04147.7 OAJ28258.1 - 3 5.6 17.8 4.9 4.9 12.4 1.2 1 0 0 1 1 1 0 Nop14-like family Ldh_1_N PF00056.18 OAJ28259.1 - 6.7e-46 155.6 0.5 9.9e-46 155.0 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 OAJ28259.1 - 7.8e-42 142.9 0.0 1.1e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 OAJ28259.1 - 9.2e-06 24.5 0.0 1.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 OAJ28259.1 - 0.0021 17.1 0.2 0.036 13.1 0.2 2.3 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.11 OAJ28259.1 - 0.038 13.2 0.1 1.4 8.1 0.0 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Mito_carr PF00153.22 OAJ28260.1 - 2.4e-45 152.1 7.8 1.2e-17 63.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S24e PF01282.14 OAJ28261.1 - 2.5e-32 110.5 0.1 3.8e-32 109.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Sec39 PF08314.6 OAJ28262.1 - 0.12 10.3 0.1 0.18 9.7 0.1 1.2 1 0 0 1 1 1 0 Secretory pathway protein Sec39 DUF2348 PF09807.4 OAJ28263.1 - 0.00021 20.5 0.0 0.00035 19.7 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) AAA_25 PF13481.1 OAJ28263.1 - 0.00061 19.2 0.1 0.00099 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 OAJ28263.1 - 0.015 14.9 0.0 0.034 13.8 0.0 1.5 1 1 0 1 1 1 0 NACHT domain Aminotran_5 PF00266.14 OAJ28264.1 - 3.1e-30 105.1 0.0 4e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MFS_1 PF07690.11 OAJ28264.1 - 2.9e-27 95.3 49.2 8.3e-27 93.8 33.4 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4028 PF13220.1 OAJ28265.1 - 0.0018 17.8 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4028) ABC2_membrane PF01061.19 OAJ28266.1 - 1.5e-13 50.4 13.7 7.1e-09 35.1 0.3 2.4 1 1 1 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 OAJ28266.1 - 5e-12 46.2 0.0 8.6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 OAJ28266.1 - 0.0021 18.0 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 OAJ28266.1 - 0.0041 16.2 0.0 0.0059 15.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.20 OAJ28267.1 - 1.4e-71 240.7 0.0 1.7e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28267.1 - 5.4e-31 107.6 0.0 7e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 OAJ28267.1 - 3.8e-13 49.7 0.9 1.2e-12 48.0 0.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 OAJ28267.1 - 1.7e-05 23.9 0.0 4.8e-05 22.4 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 OAJ28267.1 - 0.0081 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ28267.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ceramidase_alk PF04734.8 OAJ28268.1 - 3.4e-207 689.4 0.0 4.7e-206 685.7 0.0 2.2 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Abhydrolase_6 PF12697.2 OAJ28270.1 - 4.3e-06 26.7 2.6 7.4e-06 26.0 1.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ28270.1 - 0.00046 19.9 0.0 0.0008 19.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAJ28270.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF3566 PF12089.3 OAJ28272.1 - 0.8 9.7 6.5 0.46 10.5 0.6 2.4 2 0 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) DUF4389 PF14333.1 OAJ28272.1 - 8.6 6.1 8.9 1.3 8.7 1.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) ATG22 PF11700.3 OAJ28273.1 - 3.9e-114 381.7 23.9 4.5e-114 381.5 16.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 OAJ28273.1 - 5.6e-07 28.5 35.5 0.0036 16.0 2.1 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MOSC PF03473.12 OAJ28274.1 - 2.1e-11 43.3 0.0 5.4e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.14 OAJ28274.1 - 2e-08 33.3 0.0 2.3e-06 26.6 0.0 3.5 3 1 0 3 3 3 1 Aminotransferase class-V MOSC_N PF03476.11 OAJ28274.1 - 3.8e-08 33.0 0.0 0.00023 20.8 0.0 2.7 2 0 0 2 2 2 2 MOSC N-terminal beta barrel domain SKN1 PF03935.10 OAJ28275.1 - 2.3e-175 583.5 1.9 2.7e-175 583.3 1.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) GST_N PF02798.15 OAJ28276.1 - 1.1e-11 44.7 0.2 6.3e-11 42.2 0.0 2.3 2 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 OAJ28276.1 - 1.6e-10 41.0 0.0 2.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ28276.1 - 3.9e-09 36.3 0.0 8.8e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAJ28276.1 - 6.8e-09 35.6 0.0 2e-08 34.1 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAJ28276.1 - 4.2e-07 29.7 0.1 9.8e-07 28.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ28276.1 - 2.5e-05 24.6 0.0 4.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TSSC4 PF15264.1 OAJ28276.1 - 0.08 13.3 0.1 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 Bac_rhodopsin PF01036.13 OAJ28277.1 - 8.5e-51 172.3 20.5 1.1e-50 172.0 14.2 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 OAJ28277.1 - 0.4 10.0 9.7 1.2 8.5 1.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Arteri_Gl PF00951.13 OAJ28277.1 - 0.8 9.2 5.6 0.14 11.7 0.9 1.9 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein AgrB PF04647.10 OAJ28277.1 - 3.5 6.6 9.6 0.12 11.4 2.1 1.9 2 0 0 2 2 2 0 Accessory gene regulator B ABC2_membrane_3 PF12698.2 OAJ28277.1 - 4.2 6.3 17.1 4.3 6.2 0.9 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF3810 PF12725.2 OAJ28277.1 - 4.9 5.9 6.2 0.26 10.1 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF2754 PF10953.3 OAJ28277.1 - 8 6.6 7.9 8.8 6.4 4.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) Acyltransferase PF01553.16 OAJ28278.1 - 7.7e-15 54.5 0.0 2e-10 40.2 0.0 2.2 2 0 0 2 2 2 2 Acyltransferase BPL_LplA_LipB PF03099.14 OAJ28279.1 - 1.9e-12 47.3 0.0 3.2e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Pkinase PF00069.20 OAJ28280.1 - 8.1e-05 21.8 0.0 0.00015 21.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28280.1 - 0.00078 18.5 0.0 0.0015 17.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 OAJ28280.1 - 0.17 10.9 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GHMP_kinases_N PF00288.21 OAJ28282.1 - 1.6e-12 47.2 2.3 5.5e-12 45.5 1.6 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 OAJ28282.1 - 0.0019 18.3 0.0 0.0052 16.9 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal CorA PF01544.13 OAJ28283.1 - 3e-45 154.4 0.2 4.1e-45 154.0 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ACT_4 PF13291.1 OAJ28283.1 - 0.15 12.3 0.1 0.38 11.1 0.1 1.6 1 0 0 1 1 1 0 ACT domain Pkinase PF00069.20 OAJ28284.1 - 2.4e-06 26.9 0.0 3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 OAJ28284.1 - 4.8e-05 22.5 0.0 7.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ28284.1 - 0.0018 18.0 0.1 0.0025 17.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 OAJ28284.1 - 0.0033 16.5 0.0 0.0065 15.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 OAJ28284.1 - 0.16 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 OAJ28285.1 - 1.4e-05 24.3 0.0 1.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 OAJ28285.1 - 0.00025 20.1 0.0 0.00034 19.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 OAJ28285.1 - 0.014 14.4 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 OAJ28285.1 - 0.021 14.5 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltransf_25 PF13649.1 OAJ28286.1 - 0.046 14.0 0.0 16 5.9 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Mon1 PF03164.9 OAJ28287.1 - 2.9e-63 213.9 0.0 1.8e-20 72.9 0.0 4.1 4 0 0 4 4 4 4 Trafficking protein Mon1 Solute_trans_a PF03619.11 OAJ28288.1 - 4.7e-68 229.4 12.0 5.5e-68 229.2 8.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PepSY_TM_2 PF13703.1 OAJ28288.1 - 0.0073 16.4 1.4 0.013 15.6 0.2 2.2 2 0 0 2 2 2 1 PepSY-associated TM helix Nramp PF01566.13 OAJ28288.1 - 0.033 12.9 0.3 0.033 12.9 0.2 1.6 2 0 0 2 2 2 0 Natural resistance-associated macrophage protein DUF4396 PF14342.1 OAJ28288.1 - 0.21 11.7 1.9 0.65 10.1 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4396) Dopey_N PF04118.9 OAJ28289.1 - 9.3e-106 353.0 0.0 2e-105 351.9 0.0 1.5 1 0 0 1 1 1 1 Dopey, N-terminal UCR_hinge PF02320.11 OAJ28290.1 - 2e-07 30.8 2.3 3.4e-07 30.0 1.6 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein GDNF PF02351.11 OAJ28290.1 - 0.043 14.3 0.8 0.086 13.3 0.5 1.4 1 0 0 1 1 1 0 GDNF/GAS1 domain SART-1 PF03343.8 OAJ28290.1 - 0.61 8.3 7.7 0.68 8.2 5.3 1.0 1 0 0 1 1 1 0 SART-1 family Daxx PF03344.10 OAJ28290.1 - 3.3 6.0 12.4 3.7 5.9 8.6 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 OAJ28290.1 - 3.6 5.3 10.3 3.8 5.3 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 OAJ28290.1 - 6.8 5.8 9.6 8.5 5.5 6.7 1.2 1 0 0 1 1 1 0 SDA1 Pribosyltran PF00156.22 OAJ28291.1 - 6.8e-19 67.8 0.5 1.5e-18 66.7 0.3 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Yqai PF09466.5 OAJ28291.1 - 0.09 12.7 0.1 0.25 11.3 0.0 1.8 1 1 0 1 1 1 0 Hypothetical protein Yqai PRTase_2 PF15609.1 OAJ28291.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase DDE_3 PF13358.1 OAJ28292.1 - 2e-17 63.2 0.0 3.7e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 OAJ28292.1 - 0.0027 17.8 0.1 0.0027 17.8 0.1 1.6 2 0 0 2 2 2 1 Winged helix-turn helix DDE_1 PF03184.14 OAJ28292.1 - 0.015 14.4 0.0 0.064 12.3 0.0 1.8 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_33 PF13592.1 OAJ28292.1 - 0.076 12.5 0.2 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_IS630 PF01710.11 OAJ28292.1 - 0.09 12.4 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Transposase HTH_7 PF02796.10 OAJ28292.1 - 0.099 12.5 0.1 20 5.1 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase AT_hook PF02178.14 OAJ28293.1 - 5.3 7.0 10.2 0.44 10.3 1.7 3.1 2 0 0 2 2 2 0 AT hook motif Sec7_N PF12783.2 OAJ28295.1 - 6e-29 100.6 2.0 2.3e-28 98.7 0.0 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 OAJ28295.1 - 0.0008 18.8 0.0 0.0098 15.3 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) OST3_OST6 PF04756.8 OAJ28296.1 - 8.4e-16 57.9 2.4 1.6e-15 57.0 1.6 1.4 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 OAJ28296.1 - 0.0012 18.4 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin HlyIII PF03006.15 OAJ28296.1 - 5.8 6.2 10.7 0.24 10.7 0.5 2.5 3 0 0 3 3 3 0 Haemolysin-III related Cyclin PF08613.6 OAJ28297.1 - 4.3e-28 98.5 0.1 7.4e-28 97.8 0.1 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 OAJ28297.1 - 0.00013 21.5 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain NAD_kinase PF01513.16 OAJ28298.1 - 6.9e-66 221.9 0.0 3.4e-65 219.6 0.0 1.9 1 1 0 1 1 1 1 ATP-NAD kinase TFIIA PF03153.8 OAJ28298.1 - 0.14 12.0 17.5 0.33 10.8 12.2 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 OAJ28298.1 - 0.57 8.0 22.7 0.077 10.9 12.6 1.8 2 0 0 2 2 2 0 Nop14-like family Nucleoplasmin PF03066.10 OAJ28298.1 - 0.77 9.2 22.5 0.082 12.4 10.8 2.4 2 0 0 2 2 2 0 Nucleoplasmin DUF2457 PF10446.4 OAJ28298.1 - 8.1 5.0 29.8 1.5 7.4 17.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) La PF05383.12 OAJ28299.1 - 2.2e-16 59.3 0.0 3.3e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 La domain tRNA_anti-codon PF01336.20 OAJ28300.1 - 0.0042 16.9 1.2 0.008 16.0 0.8 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF966 PF06136.8 OAJ28300.1 - 0.42 9.9 13.6 0.04 13.3 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) PAP2 PF01569.16 OAJ28301.1 - 1.8e-25 89.0 6.0 1.8e-25 89.0 4.1 1.6 2 0 0 2 2 2 1 PAP2 superfamily CoA_binding_2 PF13380.1 OAJ28302.1 - 7.3e-32 109.9 0.1 8.7e-32 109.7 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 OAJ28302.1 - 5.6e-05 23.5 0.0 8.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain DUF4231 PF14015.1 OAJ28303.1 - 0.31 11.0 0.1 0.31 11.0 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Phage_integrase PF00589.17 OAJ28304.1 - 1.3e-07 31.4 0.0 2.3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family adh_short_C2 PF13561.1 OAJ28307.1 - 4.1e-29 102.0 0.1 4.1e-29 102.0 0.1 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ28307.1 - 8.7e-27 94.0 0.1 8.7e-27 94.0 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAJ28307.1 - 2.7e-12 46.7 0.1 6.3e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAJ28307.1 - 2e-05 24.1 0.2 6.5e-05 22.4 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 OAJ28307.1 - 0.077 11.8 0.1 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein OGFr_III PF04680.8 OAJ28308.1 - 6.2 7.1 7.4 1.5 9.0 1.5 2.3 2 0 0 2 2 2 0 Opioid growth factor receptor repeat DHQ_synthase PF01761.15 OAJ28309.1 - 1.1e-43 149.0 0.0 1.4e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 OAJ28309.1 - 0.0075 15.6 0.0 0.012 14.9 0.0 1.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 OAJ28310.1 - 0.019 14.3 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase GMC_oxred_N PF00732.14 OAJ28311.1 - 0.02 14.0 0.0 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 GMC oxidoreductase DUF2805 PF10985.3 OAJ28311.1 - 0.026 14.4 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) H_lectin PF09458.5 OAJ28312.1 - 0.00018 21.0 0.0 0.036 13.7 0.0 3.7 4 0 0 4 4 4 1 H-type lectin domain DUF3584 PF12128.3 OAJ28313.1 - 1.3 6.2 24.7 1.9 5.7 17.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 OAJ28313.1 - 2.6 6.6 16.5 4.2 5.9 11.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Fmp27_WPPW PF10359.4 OAJ28313.1 - 3.7 5.8 16.0 0.063 11.6 2.7 2.6 2 1 1 3 3 3 0 RNA pol II promoter Fmp27 protein domain TPR_MLP1_2 PF07926.7 OAJ28313.1 - 3.9 7.2 29.2 3.2 7.4 7.6 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ATPgrasp_Ter PF15632.1 OAJ28315.1 - 1.1e-08 34.2 0.0 2.8e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 OAJ28315.1 - 4.4e-07 29.8 0.0 9.4e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain Abhydrolase_5 PF12695.2 OAJ28315.1 - 0.045 13.4 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ28315.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Nop14 PF04147.7 OAJ28316.1 - 0.021 12.7 14.4 0.031 12.2 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 OAJ28316.1 - 0.12 10.2 1.7 0.18 9.6 1.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.8 OAJ28316.1 - 0.22 11.1 10.7 0.54 9.8 7.5 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Rpp20 PF12328.3 OAJ28316.1 - 0.75 9.4 5.1 0.11 12.1 0.6 1.7 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P CENP-B_dimeris PF09026.5 OAJ28316.1 - 6.8 7.0 14.0 0.3 11.3 5.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain VID27 PF08553.5 OAJ28316.1 - 9.2 4.3 8.9 1.2 7.3 2.9 1.7 2 0 0 2 2 2 0 VID27 cytoplasmic protein Mcp5_PH PF12814.2 OAJ28317.1 - 3e-40 136.9 0.2 1.3e-39 134.9 0.0 2.2 2 1 1 3 3 3 1 Meiotic cell cortex C-terminal pleckstrin homology DUF3166 PF11365.3 OAJ28317.1 - 0.014 15.8 2.4 0.014 15.8 1.7 8.3 6 2 3 9 9 9 0 Protein of unknown function (DUF3166) Filament PF00038.16 OAJ28317.1 - 0.82 9.0 107.3 1.7 7.9 6.4 7.1 2 2 3 5 5 5 0 Intermediate filament protein GRAB PF10375.4 OAJ28318.1 - 3.4e-05 23.3 0.7 3.4e-05 23.3 0.5 2.5 2 0 0 2 2 2 1 GRIP-related Arf-binding domain Macoilin PF09726.4 OAJ28318.1 - 0.00029 19.2 4.2 0.00029 19.2 2.9 3.9 3 1 1 4 4 3 1 Transmembrane protein TMF_DNA_bd PF12329.3 OAJ28318.1 - 0.00087 19.0 1.9 0.00087 19.0 1.3 4.8 2 2 2 5 5 5 1 TATA element modulatory factor 1 DNA binding FliJ PF02050.11 OAJ28318.1 - 0.031 14.3 43.1 0.22 11.5 6.4 3.4 1 1 2 3 3 3 0 Flagellar FliJ protein IncA PF04156.9 OAJ28318.1 - 0.15 11.6 49.4 0.017 14.7 10.9 3.3 2 1 1 3 3 3 0 IncA protein DUF812 PF05667.6 OAJ28318.1 - 0.58 8.6 29.4 0.83 8.0 5.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Myosin_tail_1 PF01576.14 OAJ28318.1 - 1.3 6.6 43.6 0.027 12.2 21.3 2.1 2 0 0 2 2 2 0 Myosin tail Bacillus_HBL PF05791.6 OAJ28318.1 - 1.9 7.8 8.9 0.73 9.1 0.7 2.4 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Reo_sigmaC PF04582.7 OAJ28318.1 - 2 7.5 16.1 4 6.5 8.3 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 OAJ28318.1 - 2.6 6.3 18.6 0.71 8.2 9.0 2.1 2 0 0 2 2 2 0 AAA domain Baculo_PEP_C PF04513.7 OAJ28318.1 - 4.4 7.1 13.5 6.1 6.6 0.3 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 OAJ28318.1 - 6.5 6.5 41.9 0.029 14.2 7.9 3.3 2 1 1 3 3 2 0 Tropomyosin like Ctr PF04145.10 OAJ28319.1 - 5.9e-17 62.0 0.1 2.5e-15 56.8 0.1 2.1 1 1 0 1 1 1 1 Ctr copper transporter family RRM_1 PF00076.17 OAJ28320.1 - 1.6e-18 66.0 0.0 3.1e-12 45.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ28320.1 - 1e-11 44.6 0.0 6.1e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CBFD_NFYB_HMF PF00808.18 OAJ28321.1 - 8.3e-08 32.1 0.3 1.4e-07 31.4 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BUD22 PF09073.5 OAJ28321.1 - 0.0017 17.4 18.3 0.0021 17.1 12.7 1.3 1 0 0 1 1 1 1 BUD22 Peptidase_S49_N PF08496.5 OAJ28321.1 - 0.023 14.4 0.8 0.023 14.4 0.6 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CDC27 PF09507.5 OAJ28321.1 - 0.11 11.7 18.9 0.12 11.5 13.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.8 OAJ28321.1 - 0.12 12.2 15.7 0.16 11.8 10.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pox_Ag35 PF03286.9 OAJ28321.1 - 0.16 11.4 20.1 0.19 11.2 7.0 2.4 1 1 1 2 2 2 0 Pox virus Ag35 surface protein CENP-T PF15511.1 OAJ28321.1 - 4.5 6.3 28.0 15 4.6 19.4 2.0 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 OAJ28321.1 - 7.4 4.9 32.7 14 4.0 22.6 1.4 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 OAJ28322.1 - 1.1 7.1 7.7 2 6.2 0.3 2.0 1 1 1 2 2 2 0 Nop14-like family Nucleo_P87 PF07267.6 OAJ28322.1 - 4 5.9 5.7 6.6 5.2 3.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DDE_1 PF03184.14 OAJ28324.1 - 1.5e-26 92.9 0.0 3.1e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease MIP-T3 PF10243.4 OAJ28324.1 - 0.4 9.0 36.1 0.61 8.4 25.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SRP-alpha_N PF04086.8 OAJ28324.1 - 1.4 8.1 24.3 2.1 7.6 16.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Borrelia_P83 PF05262.6 OAJ28324.1 - 2 6.5 32.6 3 6.0 22.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CAF-1_p150 PF11600.3 OAJ28324.1 - 2.6 7.3 56.1 4.1 6.7 38.9 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PLRV_ORF5 PF01690.12 OAJ28324.1 - 2.9 6.9 16.5 4.3 6.3 11.5 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DNA_pol_viral_N PF00242.12 OAJ28324.1 - 5.9 5.8 12.0 8.7 5.2 8.3 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SWIB PF02201.13 OAJ28325.1 - 7.8e-17 60.7 0.0 1.5e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain UPF0160 PF03690.8 OAJ28326.1 - 1e-122 409.5 0.0 1.8e-122 408.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) RNase_H2-Ydr279 PF09468.5 OAJ28326.1 - 6.7e-19 68.1 0.1 6.9e-10 38.5 0.5 4.0 2 1 0 2 2 2 2 Ydr279p protein family (RNase H2 complex component) DDE_Tnp_4 PF13359.1 OAJ28327.1 - 2.3e-07 30.5 0.0 3.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ28327.1 - 6.8e-05 22.3 0.0 8.9e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 OAJ28327.1 - 0.051 13.1 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain zf-CCCH_2 PF14608.1 OAJ28328.1 - 1.6e-07 31.0 19.1 4.3e-06 26.5 4.3 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type Ank_2 PF12796.2 OAJ28328.1 - 2.8e-07 30.7 0.0 5.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ28328.1 - 5.6e-06 25.8 0.0 1.5e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 OAJ28328.1 - 9.6e-05 22.5 0.1 0.00044 20.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ28328.1 - 0.0001 22.2 0.0 0.00024 21.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat zf-CCCH PF00642.19 OAJ28328.1 - 0.0007 19.2 11.5 0.024 14.3 1.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_4 PF13637.1 OAJ28328.1 - 0.0015 18.9 0.0 0.0041 17.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PPR_2 PF13041.1 OAJ28329.1 - 0.011 15.6 0.0 0.18 11.7 0.0 2.8 2 0 0 2 2 2 0 PPR repeat family Pkinase PF00069.20 OAJ28330.1 - 1.5e-73 247.1 0.0 2e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28330.1 - 1.5e-31 109.4 0.0 2.3e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ28330.1 - 3.4e-07 29.5 0.3 0.00083 18.4 0.1 2.4 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.17 OAJ28330.1 - 0.00068 19.0 0.1 0.0012 18.2 0.1 1.4 1 0 0 1 1 1 1 RIO1 family SEEEED PF14797.1 OAJ28330.1 - 0.12 12.5 11.2 0.18 11.9 7.8 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex RRM_1 PF00076.17 OAJ28331.1 - 5.4e-20 70.7 0.0 5.2e-12 45.2 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ28331.1 - 9.7e-17 60.7 0.0 1.8e-09 37.4 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ28331.1 - 7.1e-10 38.5 0.1 0.0013 18.5 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDK2AP PF09806.4 OAJ28332.1 - 0.007 16.6 2.8 0.007 16.6 2.0 2.5 3 1 0 3 3 3 1 Cyclin-dependent kinase 2-associated protein DUF3357 PF11837.3 OAJ28332.1 - 0.026 14.3 2.9 0.72 9.7 0.7 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF4366 PF14283.1 OAJ28332.1 - 0.66 9.3 0.0 0.66 9.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) Macoilin PF09726.4 OAJ28332.1 - 3.4 5.8 5.3 6.1 4.9 3.7 1.3 1 0 0 1 1 1 0 Transmembrane protein FA_desaturase PF00487.19 OAJ28333.1 - 0.18 11.1 0.9 0.36 10.2 0.6 1.4 1 0 0 1 1 1 0 Fatty acid desaturase DUF2077 PF09850.4 OAJ28333.1 - 0.26 10.6 3.6 0.21 10.9 1.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) Lipase_3 PF01764.20 OAJ28334.1 - 3.2e-11 43.0 0.0 4.3e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) Colicin_immun PF09204.5 OAJ28334.1 - 0.18 11.8 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial self-protective colicin-like immunity Lipase_3 PF01764.20 OAJ28335.1 - 4.9e-06 26.2 0.1 4.4e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 Lipase (class 3) Phage_holin_2 PF04550.7 OAJ28336.1 - 0.074 13.1 3.8 30 4.8 0.1 3.1 3 0 0 3 3 3 0 Phage holin family 2 Abhydrolase_3 PF07859.8 OAJ28337.1 - 5.1e-49 166.7 0.1 8.1e-49 166.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAJ28337.1 - 9.7e-13 47.4 0.0 2.4e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 OAJ28337.1 - 0.00027 20.7 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S3 PF00944.14 OAJ28338.1 - 0.035 13.5 0.3 0.047 13.1 0.2 1.2 1 0 0 1 1 1 0 Alphavirus core protein AAA_10 PF12846.2 OAJ28339.1 - 0.6 9.4 3.1 1.1 8.6 2.1 1.3 1 0 0 1 1 1 0 AAA-like domain RNase_T PF00929.19 OAJ28340.1 - 1.8e-23 83.5 0.0 2.6e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 OAJ28340.1 - 0.0016 17.9 0.0 0.005 16.3 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease DUF1658 PF07871.6 OAJ28340.1 - 0.012 15.1 1.1 0.012 15.1 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) Sporozoite_P67 PF05642.6 OAJ28340.1 - 0.54 8.0 4.5 1 7.1 2.7 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 OAJ28340.1 - 2 8.7 6.9 0.91 9.8 2.9 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 OAJ28340.1 - 2.8 5.8 5.5 3.6 5.4 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Coq4 PF05019.8 OAJ28341.1 - 1.1e-80 269.7 0.0 1.4e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 MMS19_N PF14500.1 OAJ28342.1 - 1e-60 205.2 0.8 2.1e-59 200.9 0.5 2.2 1 1 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 OAJ28342.1 - 5.3e-15 55.0 0.0 1.3e-13 50.5 0.0 2.8 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal Glyco_hydro_20 PF00728.17 OAJ28343.1 - 2.4e-24 86.1 0.0 3.9e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF775 PF05603.7 OAJ28344.1 - 3e-36 124.8 0.0 3.5e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) FimP PF09766.4 OAJ28345.1 - 0.0078 15.3 1.7 0.012 14.7 1.2 1.3 1 0 0 1 1 1 1 Fms-interacting protein TPR_16 PF13432.1 OAJ28345.1 - 0.0083 16.7 0.3 0.027 15.1 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat FAT PF02259.18 OAJ28345.1 - 0.035 13.1 1.3 0.043 12.7 0.9 1.2 1 0 0 1 1 1 0 FAT domain DUF1090 PF06476.7 OAJ28345.1 - 0.035 13.7 0.2 0.076 12.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) THOC7 PF05615.8 OAJ28345.1 - 0.038 14.2 1.6 0.16 12.1 0.4 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 TPR_14 PF13428.1 OAJ28345.1 - 0.055 14.1 0.6 18 6.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ28345.1 - 0.063 12.9 2.5 4.4 7.0 0.0 2.9 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 OAJ28345.1 - 0.13 12.2 3.1 13 5.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ28345.1 - 1.4 8.6 4.5 7 6.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.19 OAJ28346.1 - 7e-13 48.4 0.0 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAJ28346.1 - 1.9e-05 24.7 0.0 2.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAJ28346.1 - 9.8e-05 22.3 0.0 0.0002 21.3 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ28346.1 - 0.00046 19.8 0.0 0.00082 19.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 OAJ28346.1 - 0.0014 18.7 0.0 0.0034 17.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAJ28346.1 - 0.0025 17.6 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 OAJ28346.1 - 0.0032 17.6 0.0 0.004 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAJ28346.1 - 0.008 16.0 0.1 0.25 11.1 0.1 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 OAJ28346.1 - 0.067 13.0 0.0 0.087 12.6 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Raptor_N PF14538.1 OAJ28347.1 - 2.2e-49 167.2 0.0 2.2e-49 167.2 0.0 2.0 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 OAJ28347.1 - 3.7e-08 32.9 2.7 1 9.3 0.0 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT PF02985.17 OAJ28347.1 - 0.0022 17.9 6.6 0.41 10.8 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 OAJ28347.1 - 0.035 14.5 1.3 0.99 9.9 0.0 3.7 2 1 1 3 3 3 0 HEAT-like repeat TFIIA PF03153.8 OAJ28347.1 - 0.044 13.6 15.4 0.098 12.5 10.7 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BBS2_Mid PF14783.1 OAJ28347.1 - 0.052 13.3 0.0 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.4 OAJ28347.1 - 0.11 12.2 0.1 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain BRF1 PF07741.8 OAJ28347.1 - 7.6 6.8 9.6 26 5.1 6.6 1.9 1 0 0 1 1 1 0 Brf1-like TBP-binding domain CLASP_N PF12348.3 OAJ28348.1 - 1.2e-67 227.6 5.2 9.2e-55 185.4 0.2 3.3 3 0 0 3 3 3 3 CLASP N terminal HEAT PF02985.17 OAJ28348.1 - 1.9e-07 30.5 1.4 0.043 13.9 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat DPBB_1 PF03330.13 OAJ28349.1 - 1.7e-07 31.1 0.0 3.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ28349.1 - 0.00092 18.8 0.4 0.0016 18.1 0.2 1.3 1 0 0 1 1 1 1 Barwin family DUF2722 PF10846.3 OAJ28349.1 - 0.098 11.6 1.6 0.13 11.2 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Lipase_3 PF01764.20 OAJ28350.1 - 8.4e-14 51.3 0.0 2.1e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) PsaL PF02605.10 OAJ28350.1 - 0.0088 15.5 0.1 0.034 13.6 0.0 2.0 2 0 0 2 2 2 1 Photosystem I reaction centre subunit XI Mito_carr PF00153.22 OAJ28351.1 - 7.3e-49 163.4 5.6 2.7e-16 59.0 0.0 3.9 4 0 0 4 4 4 3 Mitochondrial carrier protein DSBA PF01323.15 OAJ28353.1 - 1.5e-21 76.8 0.0 1.9e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Zn_clus PF00172.13 OAJ28354.1 - 1.5e-08 34.3 2.7 3e-08 33.4 1.8 1.5 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TraI PF07057.6 OAJ28355.1 - 0.12 12.4 1.6 0.12 12.3 1.1 1.2 1 0 0 1 1 1 0 DNA helicase TraI TBP PF00352.16 OAJ28356.1 - 2.3e-68 225.5 0.2 2.8e-34 116.3 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 OAJ28356.1 - 0.00018 21.4 0.0 0.67 10.0 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) N_NLPC_P60 PF12912.2 OAJ28357.1 - 0.083 12.9 0.2 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term Glucos_trans_II PF14264.1 OAJ28357.1 - 0.086 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII zf-RING_2 PF13639.1 OAJ28359.1 - 6.6e-09 35.4 11.0 0.00014 21.6 0.5 2.4 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ28359.1 - 7e-08 32.3 16.9 1.5e-05 24.8 3.6 2.9 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 OAJ28359.1 - 1.4e-06 27.7 4.2 9.1e-05 21.7 0.1 3.0 2 1 2 4 4 4 2 Rtf2 RING-finger zf-RING_5 PF14634.1 OAJ28359.1 - 2.5e-06 27.0 12.3 1.7e-05 24.4 1.1 2.9 2 1 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAJ28359.1 - 7.6e-06 25.5 13.1 0.011 15.3 3.4 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 OAJ28359.1 - 0.002 17.9 8.9 0.0028 17.5 2.0 2.8 2 1 0 2 2 2 1 FYVE zinc finger zf-C3HC4_4 PF15227.1 OAJ28359.1 - 0.026 14.4 4.3 0.026 14.4 3.0 3.3 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 OAJ28359.1 - 0.11 12.1 17.0 0.15 11.7 3.6 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Calici_PP_N PF08405.6 OAJ28359.1 - 0.13 11.0 0.1 0.27 10.0 0.1 1.4 1 0 0 1 1 1 0 Viral polyprotein N-terminal TerY-C PF15616.1 OAJ28359.1 - 0.21 11.5 11.0 0.21 11.5 0.3 3.2 2 1 1 3 3 3 0 TerY-C metal binding domain zf-RING_UBOX PF13445.1 OAJ28359.1 - 0.36 10.5 8.8 4.7 6.9 2.0 2.7 2 0 0 2 2 2 0 RING-type zinc-finger Atg14 PF10186.4 OAJ28359.1 - 1.5 7.6 12.1 2.2 7.1 8.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zf-RING_6 PF14835.1 OAJ28359.1 - 6.7 6.5 11.0 0.48 10.2 0.4 2.8 3 0 0 3 3 3 0 zf-RING of BARD1-type protein DUF500 PF04366.7 OAJ28360.1 - 3.7e-36 123.3 0.4 7.6e-36 122.3 0.3 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_9 PF14604.1 OAJ28360.1 - 3.1e-13 49.0 0.0 5.6e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ28360.1 - 1e-11 44.0 0.0 1.8e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ28360.1 - 6e-10 38.4 0.0 1.2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain AA_permease_2 PF13520.1 OAJ28361.1 - 1.9e-40 138.7 24.7 6.9e-40 136.8 17.1 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAJ28361.1 - 1.4e-12 46.7 15.9 1.4e-12 46.7 11.0 1.9 2 0 0 2 2 2 1 Amino acid permease ETF_QO PF05187.8 OAJ28363.1 - 6e-40 135.6 0.1 1.3e-39 134.5 0.0 1.6 2 0 0 2 2 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 OAJ28363.1 - 2.1e-08 33.5 1.5 0.00089 18.2 0.2 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ28363.1 - 6.9e-08 31.7 0.2 3.9e-05 22.6 0.2 2.2 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 OAJ28363.1 - 7.4e-07 29.1 0.0 2.2e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAJ28363.1 - 6.3e-05 22.9 0.0 0.00015 21.7 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ28363.1 - 6.4e-05 21.5 0.2 0.0001 20.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 OAJ28363.1 - 9.9e-05 21.5 0.1 0.00066 18.8 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 OAJ28363.1 - 0.00021 20.3 0.0 0.00033 19.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Fer4_7 PF12838.2 OAJ28363.1 - 0.0011 19.3 1.2 0.0027 18.0 0.8 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_oxidored PF12831.2 OAJ28363.1 - 0.0018 17.4 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAJ28363.1 - 0.0022 17.7 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Fer4_10 PF13237.1 OAJ28363.1 - 0.0022 17.7 0.8 0.0041 16.8 0.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox_3 PF13738.1 OAJ28363.1 - 0.0031 17.5 0.0 0.0059 16.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_21 PF14697.1 OAJ28363.1 - 0.0078 16.0 0.3 0.016 15.0 0.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox PF00070.22 OAJ28363.1 - 0.0083 16.5 0.2 0.3 11.5 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ28363.1 - 0.02 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_2 PF12797.2 OAJ28363.1 - 0.053 13.4 0.4 0.14 12.0 0.3 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain FAD_binding_3 PF01494.14 OAJ28363.1 - 0.13 11.2 0.1 0.24 10.3 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Fer4_6 PF12837.2 OAJ28363.1 - 1.5 8.8 4.8 0.45 10.4 0.6 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Transposase_21 PF02992.9 OAJ28364.1 - 3.5e-08 32.8 0.0 1e-07 31.2 0.0 1.8 2 1 0 2 2 2 1 Transposase family tnp2 Zn-ribbon_8 PF09723.5 OAJ28364.1 - 0.17 11.8 0.9 0.48 10.4 0.6 1.8 1 0 0 1 1 1 0 Zinc ribbon domain Beta_elim_lyase PF01212.16 OAJ28365.1 - 1.7e-60 204.6 0.0 2.4e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DUF1903 PF08991.5 OAJ28365.1 - 1.5e-23 82.7 6.4 3.2e-23 81.6 4.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) Aminotran_1_2 PF00155.16 OAJ28365.1 - 1.6e-05 24.0 0.0 0.00082 18.4 0.0 2.2 3 0 0 3 3 3 2 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 OAJ28365.1 - 0.00017 20.7 0.0 0.00035 19.7 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family bZIP_1 PF00170.16 OAJ28366.1 - 1.5e-08 34.5 6.5 3.4e-06 26.8 2.5 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 OAJ28366.1 - 2.2e-06 27.4 4.9 2.2e-06 27.4 3.4 1.5 2 0 0 2 2 2 1 Basic region leucine zipper DUF3450 PF11932.3 OAJ28366.1 - 0.0072 15.6 1.7 0.011 15.0 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Glutaredoxin2_C PF04399.8 OAJ28366.1 - 0.075 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Ribosomal_S20p PF01649.13 OAJ28366.1 - 0.12 12.7 1.8 0.18 12.1 0.7 1.7 2 0 0 2 2 2 0 Ribosomal protein S20 Spc7 PF08317.6 OAJ28366.1 - 0.21 10.1 3.4 0.34 9.5 2.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 OAJ28366.1 - 3.5 6.4 6.0 5.1 5.9 4.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CDC50 PF03381.10 OAJ28368.1 - 6.1e-88 294.5 0.0 7.5e-88 294.3 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Pertus-S4-tox PF09275.5 OAJ28368.1 - 0.15 12.1 0.1 0.59 10.2 0.0 2.0 2 0 0 2 2 2 0 Pertussis toxin S4 subunit MHYT PF03707.11 OAJ28369.1 - 5.3e-12 45.6 19.8 2.9e-06 27.2 1.3 4.6 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat APC_CDC26 PF10471.4 OAJ28370.1 - 4.5e-07 30.5 4.7 1.3e-06 29.0 3.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 RNR_inhib PF08591.5 OAJ28370.1 - 0.11 13.4 1.4 0.29 12.0 1.0 1.6 1 1 1 2 2 2 0 Ribonucleotide reductase inhibitor ESCRT-II PF05871.7 OAJ28371.1 - 2.4e-44 150.6 0.0 7.2e-44 149.0 0.0 1.7 1 1 1 2 2 2 1 ESCRT-II complex subunit FeoC PF09012.5 OAJ28371.1 - 0.15 11.7 0.0 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 FeoC like transcriptional regulator Fis1_TPR_C PF14853.1 OAJ28372.1 - 9.6e-24 83.0 0.3 1.5e-23 82.4 0.2 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 OAJ28372.1 - 2.3e-13 49.1 0.0 4.9e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 OAJ28372.1 - 0.00092 18.9 0.6 0.0028 17.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ28372.1 - 0.0012 19.4 0.4 0.011 16.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ28372.1 - 0.028 14.8 1.9 17 6.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ28372.1 - 0.05 14.2 1.3 0.42 11.3 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ28372.1 - 0.077 13.3 1.3 0.4 11.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ28372.1 - 0.24 11.9 1.0 0.79 10.3 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat UPF0016 PF01169.14 OAJ28373.1 - 8.4e-43 144.3 26.7 1.3e-22 79.7 5.9 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Ion_trans PF00520.26 OAJ28373.1 - 3.6e-05 23.0 0.9 3.6e-05 23.0 0.6 2.0 2 1 0 2 2 2 1 Ion transport protein MttA_Hcf106 PF02416.11 OAJ28373.1 - 0.17 11.0 1.1 17 4.6 0.0 2.5 2 0 0 2 2 2 0 mttA/Hcf106 family DUF2678 PF10856.3 OAJ28373.1 - 0.22 11.2 2.1 0.24 11.1 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) DUF308 PF03729.8 OAJ28373.1 - 4.6 7.3 16.6 0.6 10.1 0.2 3.3 4 1 0 4 4 4 0 Short repeat of unknown function (DUF308) TrkH PF02386.11 OAJ28374.1 - 1.8e-89 299.7 10.3 2.1e-87 293.0 2.4 2.1 2 0 0 2 2 2 2 Cation transport protein FMN_dh PF01070.13 OAJ28376.1 - 1e-118 396.3 0.0 1.2e-118 395.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 OAJ28376.1 - 6.5e-21 73.9 0.6 1.2e-20 73.0 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 OAJ28376.1 - 1.1e-05 24.5 0.0 1.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 OAJ28376.1 - 0.00042 19.3 0.0 0.00081 18.3 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 OAJ28376.1 - 0.041 13.0 0.1 0.064 12.3 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Vps5 PF09325.5 OAJ28376.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Vps5 C terminal like F-box-like PF12937.2 OAJ28377.1 - 0.00036 20.1 0.3 0.0094 15.6 0.0 3.0 2 1 0 2 2 2 1 F-box-like Sporozoite_P67 PF05642.6 OAJ28377.1 - 0.19 9.5 0.4 0.37 8.6 0.3 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen F-box PF00646.28 OAJ28377.1 - 0.27 10.9 2.0 2.7 7.7 0.2 2.4 2 0 0 2 2 2 0 F-box domain Aldedh PF00171.17 OAJ28378.1 - 4e-180 599.0 1.0 4.6e-180 598.8 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Nop14 PF04147.7 OAJ28379.1 - 0.007 14.3 4.8 0.01 13.8 3.3 1.1 1 0 0 1 1 1 1 Nop14-like family DUF4228 PF14009.1 OAJ28379.1 - 0.063 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) TRAP_alpha PF03896.11 OAJ28379.1 - 1 8.3 6.0 1.9 7.4 3.4 1.8 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit TFIIA PF03153.8 OAJ28380.1 - 0.14 12.0 10.1 1.9 8.2 5.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NAP PF00956.13 OAJ28381.1 - 1.1e-31 109.7 0.7 3.1e-31 108.3 0.5 1.6 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) DUF4611 PF15387.1 OAJ28381.1 - 4.9 7.3 8.4 0.44 10.7 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) dCMP_cyt_deam_1 PF00383.17 OAJ28382.1 - 5.1e-07 29.2 3.2 0.054 13.1 2.9 3.5 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Stm1_N PF09598.5 OAJ28383.1 - 0.44 11.2 4.2 0.93 10.2 2.9 1.6 1 0 0 1 1 1 0 Stm1 zf-Tim10_DDP PF02953.10 OAJ28384.1 - 2.9e-19 68.0 2.1 3.7e-19 67.7 1.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Flagellin_N PF00669.15 OAJ28384.1 - 0.02 14.6 0.2 0.026 14.3 0.1 1.1 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region FANCI_S3 PF14677.1 OAJ28384.1 - 0.075 12.4 0.3 0.091 12.1 0.2 1.2 1 0 0 1 1 1 0 FANCI solenoid 3 Phage_int_SAM_1 PF02899.12 OAJ28385.1 - 0.029 14.5 0.0 0.07 13.2 0.0 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain FAM220 PF15487.1 OAJ28385.1 - 0.12 11.7 5.0 0.17 11.2 3.5 1.2 1 0 0 1 1 1 0 FAM220 family DUF566 PF04484.7 OAJ28385.1 - 1.5 8.2 6.8 2 7.8 4.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) SR-25 PF10500.4 OAJ28385.1 - 1.7 8.0 8.7 2.6 7.4 6.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rubella_Capsid PF05750.6 OAJ28385.1 - 2.3 7.5 8.3 4.7 6.5 5.3 1.6 1 1 0 2 2 2 0 Rubella capsid protein FAD_binding_4 PF01565.18 OAJ28386.1 - 1.5e-13 50.3 1.6 2.8e-13 49.5 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAJ28386.1 - 7.6e-09 35.3 0.5 1.9e-08 34.0 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like WD40 PF00400.27 OAJ28387.1 - 7.9e-17 60.4 9.1 1.9e-06 27.5 0.1 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ArfGap PF01412.13 OAJ28388.1 - 2.9e-32 110.9 0.4 5.2e-32 110.0 0.3 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 OAJ28388.1 - 7.7e-08 32.4 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF1724 PF08350.5 OAJ28388.1 - 0.52 9.8 0.2 1 8.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) RR_TM4-6 PF06459.7 OAJ28389.1 - 0.41 10.4 5.2 0.88 9.4 3.6 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Phage_integrase PF00589.17 OAJ28390.1 - 0.00019 21.1 0.0 0.00024 20.8 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family FimP PF09766.4 OAJ28392.1 - 4e-23 82.0 11.6 5e-23 81.7 8.0 1.1 1 0 0 1 1 1 1 Fms-interacting protein Mating_N PF12731.2 OAJ28392.1 - 0.082 12.7 0.4 0.18 11.7 0.3 1.6 1 0 0 1 1 1 0 Mating-type protein beta 1 DUF1376 PF07120.6 OAJ28392.1 - 0.21 11.7 3.6 1.6 8.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1376) HAUS-augmin3 PF14932.1 OAJ28392.1 - 1.6 7.8 13.2 4.9 6.2 9.1 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 V_ATPase_I PF01496.14 OAJ28392.1 - 2.1 6.0 6.7 12 3.6 4.6 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 OAJ28392.1 - 4.6 6.8 17.4 6.1 6.3 0.6 2.2 1 1 1 2 2 2 0 IncA protein HsbA PF12296.3 OAJ28393.1 - 2.1e-12 46.9 1.9 2.9e-12 46.5 1.3 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A WPP PF13943.1 OAJ28393.1 - 0.17 12.0 0.8 0.23 11.6 0.0 1.6 2 0 0 2 2 2 0 WPP domain Ribosomal_L35p PF01632.14 OAJ28394.1 - 4.2e-11 42.5 1.0 7e-11 41.8 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L35 HsbA PF12296.3 OAJ28395.1 - 4.5e-12 45.9 4.5 6.2e-12 45.4 3.1 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A CheZ PF04344.8 OAJ28395.1 - 0.0036 16.9 0.1 0.0047 16.6 0.1 1.1 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ adh_short_C2 PF13561.1 OAJ28396.1 - 8.4e-24 84.6 0.0 1.5e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 OAJ28396.1 - 7.5e-23 81.2 1.0 1.7e-22 80.1 0.7 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 OAJ28396.1 - 4.6e-16 58.7 0.8 1.4e-15 57.2 0.5 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 OAJ28396.1 - 5.8e-14 51.8 0.0 1.3e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.20 OAJ28396.1 - 2.5e-08 34.0 0.0 8.7e-08 32.2 0.0 2.1 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.18 OAJ28396.1 - 0.0021 17.1 0.1 0.0045 16.0 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PI3_PI4_kinase PF00454.22 OAJ28397.1 - 1.6e-32 112.8 0.0 2.5e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase K_oxygenase PF13434.1 OAJ28398.1 - 9.3e-87 291.1 0.0 1.8e-86 290.1 0.0 1.5 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAJ28398.1 - 1.1e-08 35.0 0.0 2.7e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 OAJ28398.1 - 4.8e-05 23.5 0.0 0.00033 20.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ28398.1 - 0.0071 16.7 0.0 0.035 14.5 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ABC_membrane PF00664.18 OAJ28399.1 - 5.3e-80 268.7 26.0 1.1e-42 146.3 3.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ28399.1 - 7.8e-62 207.5 0.0 2.8e-31 108.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAJ28399.1 - 1.5e-12 47.2 4.0 7.8e-05 21.9 0.2 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 OAJ28399.1 - 3e-07 29.8 0.1 0.035 13.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.12 OAJ28399.1 - 9.3e-07 28.8 0.0 0.014 15.1 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function DUF87 AAA_17 PF13207.1 OAJ28399.1 - 1.3e-06 29.2 0.0 0.076 13.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 OAJ28399.1 - 7.1e-06 26.1 0.0 0.7 9.8 0.0 4.3 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 OAJ28399.1 - 2.3e-05 24.5 1.3 3.3 7.8 0.1 4.2 3 1 0 4 4 4 1 AAA domain ABC_ATPase PF09818.4 OAJ28399.1 - 2.8e-05 22.8 0.1 0.043 12.4 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.13 OAJ28399.1 - 9.4e-05 21.9 0.1 0.014 14.8 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.1 OAJ28399.1 - 0.00011 22.0 0.4 0.87 9.5 0.1 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 OAJ28399.1 - 0.00014 21.9 3.6 0.25 11.2 0.3 3.4 2 2 0 2 2 2 2 AAA ATPase domain PRK PF00485.13 OAJ28399.1 - 0.00042 19.9 0.2 0.77 9.2 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 OAJ28399.1 - 0.00049 20.4 0.5 1.2 9.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 OAJ28399.1 - 0.0005 19.3 0.0 0.23 10.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 OAJ28399.1 - 0.00083 18.5 0.0 1.5 7.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 OAJ28399.1 - 0.0011 18.8 0.7 2.7 7.8 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_10 PF12846.2 OAJ28399.1 - 0.0013 18.2 3.7 2.8 7.2 0.1 3.9 4 0 0 4 4 4 2 AAA-like domain AAA_30 PF13604.1 OAJ28399.1 - 0.0016 18.0 0.0 0.87 9.1 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 OAJ28399.1 - 0.0025 17.2 0.2 2 7.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain APS_kinase PF01583.15 OAJ28399.1 - 0.0055 16.3 0.0 2 8.0 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase MobB PF03205.9 OAJ28399.1 - 0.011 15.4 0.1 7.5 6.2 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 OAJ28399.1 - 0.015 13.9 0.0 3.3 6.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit TrwB_AAD_bind PF10412.4 OAJ28399.1 - 0.088 11.4 0.0 13 4.2 0.0 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.1 OAJ28399.1 - 0.088 13.1 0.0 15 5.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 OAJ28399.1 - 0.3 10.5 0.4 12 5.3 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Helicase_C PF00271.26 OAJ28400.1 - 3.2e-07 30.1 0.1 2.9e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ28400.1 - 2.9e-06 26.9 0.0 9.9e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Fungal_trans PF04082.13 OAJ28403.1 - 8.5e-21 73.9 0.0 2.2e-20 72.6 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ28403.1 - 3.3e-09 36.4 10.9 5.5e-09 35.7 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain H_lectin PF09458.5 OAJ28404.1 - 1.1e-14 53.8 0.0 9.9e-07 28.3 0.0 2.6 2 0 0 2 2 2 2 H-type lectin domain Rad51 PF08423.6 OAJ28405.1 - 4.2e-09 35.7 0.0 1.1e-08 34.2 0.0 1.6 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 OAJ28405.1 - 1.5e-07 30.9 0.2 4.5e-07 29.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 OAJ28405.1 - 1.4e-05 24.3 0.1 2.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 OAJ28405.1 - 0.00012 21.2 0.1 0.00026 20.1 0.1 1.5 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.1 OAJ28405.1 - 0.006 16.3 0.2 0.03 14.0 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain PAXNEB PF05625.6 OAJ28405.1 - 0.17 10.6 0.4 0.33 9.7 0.1 1.5 2 0 0 2 2 2 0 PAXNEB protein HSP20 PF00011.16 OAJ28406.1 - 2.3e-17 62.7 0.9 4.3e-12 45.7 0.1 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family EPSP_synthase PF00275.15 OAJ28407.1 - 6.5e-46 156.5 0.0 7.9e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Pkinase PF00069.20 OAJ28409.1 - 2.5e-73 246.4 0.0 4e-73 245.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28409.1 - 3e-35 121.5 0.0 5.1e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ28409.1 - 0.00089 18.2 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 OAJ28409.1 - 0.14 10.9 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SNARE PF05739.14 OAJ28410.1 - 3.3e-05 23.4 0.0 4.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 OAJ28410.1 - 0.03 13.7 0.2 0.039 13.3 0.1 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 L51_S25_CI-B8 PF05047.11 OAJ28411.1 - 8.5e-10 38.2 0.2 1.3e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PEX11 PF05648.9 OAJ28412.1 - 9.2e-14 51.2 0.0 1.6e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Abhydrolase_3 PF07859.8 OAJ28413.1 - 1.2e-21 77.2 0.1 3.6e-21 75.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Transposase_21 PF02992.9 OAJ28413.1 - 1.4e-12 47.2 0.0 3.2e-12 46.0 0.0 1.5 1 1 0 1 1 1 1 Transposase family tnp2 Abhydrolase_5 PF12695.2 OAJ28413.1 - 2.5e-07 30.5 0.0 1.2e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF4218 PF13960.1 OAJ28413.1 - 5.9e-05 22.5 0.1 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Cutinase PF01083.17 OAJ28413.1 - 0.0076 16.0 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Cutinase Dimer_Tnp_hAT PF05699.9 OAJ28414.1 - 1.3e-10 40.7 0.0 3e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Chs3p PF12271.3 OAJ28415.1 - 1.5e-11 43.8 0.2 1.8e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit ATP-synt_ab_N PF02874.18 OAJ28415.1 - 5.2e-07 29.7 0.2 8.3e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RVT_2 PF07727.9 OAJ28416.1 - 6.1e-76 254.6 0.0 8.1e-76 254.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 OAJ28416.1 - 0.057 13.1 0.0 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase-like tRNA-synt_1d PF00750.14 OAJ28417.1 - 1.4e-82 277.3 1.6 1.9e-82 276.9 1.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 OAJ28417.1 - 9.6e-21 73.9 0.0 4e-20 71.9 0.0 2.2 2 0 0 2 2 2 1 DALR anticodon binding domain HsbA PF12296.3 OAJ28418.1 - 4.9e-13 49.0 14.0 7.2e-13 48.4 9.7 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF1307 PF06998.6 OAJ28418.1 - 0.015 15.3 0.3 0.023 14.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1307) DivIVA PF05103.8 OAJ28418.1 - 0.052 13.6 1.0 0.082 12.9 0.7 1.2 1 0 0 1 1 1 0 DivIVA protein WAC_Acf1_DNA_bd PF10537.4 OAJ28419.1 - 6.9e-34 116.0 0.0 1.7e-33 114.8 0.0 1.7 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 OAJ28419.1 - 1.4e-10 40.8 0.0 3.4e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 OAJ28419.1 - 1.3e-05 24.9 0.3 3.3e-05 23.6 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 OAJ28419.1 - 0.027 14.4 0.1 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 OAJ28419.1 - 0.094 12.5 1.1 0.21 11.3 0.1 2.2 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 3 DUF3275 PF11679.3 OAJ28419.1 - 4.6 6.8 15.7 0.1 12.2 1.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3275) rve PF00665.21 OAJ28422.1 - 4.4e-15 55.8 0.0 1.1e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ28422.1 - 1.8e-07 30.7 0.0 3.4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PH_4 PF15404.1 OAJ28423.1 - 9.1e-30 103.5 0.1 3.6e-29 101.6 0.0 2.1 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 OAJ28423.1 - 0.0019 18.3 0.0 8.4 6.6 0.0 3.9 4 0 0 4 4 4 2 PH domain Rad60-SLD PF11976.3 OAJ28424.1 - 7.9e-11 41.4 0.1 0.22 11.2 0.0 5.7 6 0 0 6 6 6 3 Ubiquitin-2 like Rad60 SUMO-like Asp_protease_2 PF13650.1 OAJ28424.1 - 3.6e-07 30.5 0.1 1.1e-06 29.0 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ28424.1 - 0.0083 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ28424.1 - 0.012 15.4 0.0 0.04 13.8 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.5 OAJ28424.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Ribonuclease PF00545.15 OAJ28425.1 - 1e-15 57.5 0.8 1.4e-15 57.0 0.6 1.3 1 1 0 1 1 1 1 ribonuclease adh_short PF00106.20 OAJ28426.1 - 1.1e-24 87.2 3.0 2.2e-24 86.2 2.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ28426.1 - 1.8e-11 44.0 0.8 3.4e-11 43.1 0.5 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ28426.1 - 6.4e-11 42.4 0.0 7.6e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UPF1_Zn_bind PF09416.5 OAJ28428.1 - 6.7e-74 246.5 8.6 6.2e-73 243.4 5.5 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 OAJ28428.1 - 1.1e-58 197.8 0.0 3.2e-58 196.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 OAJ28428.1 - 7e-56 189.4 1.4 1e-55 188.8 1.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ28428.1 - 1.4e-12 47.1 0.3 4.9e-12 45.4 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 OAJ28428.1 - 2.1e-11 43.7 0.0 2.9e-10 40.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 OAJ28428.1 - 2.2e-07 30.8 0.0 5.3e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 OAJ28428.1 - 1.6e-05 24.5 0.9 0.24 10.8 0.0 3.4 2 1 2 4 4 4 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 OAJ28428.1 - 4.9e-05 22.4 0.3 0.00075 18.5 0.0 2.6 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 OAJ28428.1 - 0.00027 20.6 0.1 0.001 18.7 0.1 2.0 1 1 0 1 1 1 1 Helicase SRP54 PF00448.17 OAJ28428.1 - 0.016 14.6 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PIF1 PF05970.9 OAJ28428.1 - 0.018 13.9 0.1 0.96 8.3 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_10 PF12846.2 OAJ28428.1 - 0.049 13.0 0.0 0.086 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 OAJ28428.1 - 0.05 13.7 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 OAJ28428.1 - 0.054 12.9 0.3 0.13 11.7 0.2 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase KaiC PF06745.8 OAJ28428.1 - 0.069 12.2 0.0 0.23 10.5 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA PF00004.24 OAJ28428.1 - 0.097 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 OAJ28428.1 - 0.13 11.4 0.0 0.31 10.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ADH_N PF08240.7 OAJ28429.1 - 2e-07 30.7 0.0 3.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ28429.1 - 9e-07 28.4 0.0 3.7e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ApbA PF02558.11 OAJ28429.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Acyl-CoA_dh_2 PF08028.6 OAJ28430.1 - 1.2e-14 54.6 0.1 2.2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAJ28430.1 - 4.4e-06 27.2 0.1 1e-05 26.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 OAJ28430.1 - 0.0025 17.9 1.2 0.0079 16.3 0.1 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain GP11 PF08677.5 OAJ28432.1 - 0.1 11.7 0.3 0.15 11.1 0.2 1.2 1 0 0 1 1 1 0 GP11 baseplate wedge protein Pkinase PF00069.20 OAJ28433.1 - 7.1e-47 159.7 0.0 1.6e-44 152.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28433.1 - 2.7e-16 59.4 0.0 7.6e-15 54.6 0.0 2.7 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ28433.1 - 0.00088 18.3 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ28433.1 - 0.0061 15.6 0.0 0.0097 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 OAJ28433.1 - 0.71 9.1 0.0 1.3 8.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Nucleoplasmin PF03066.10 OAJ28433.1 - 0.77 9.2 9.6 2.6 7.5 0.3 3.4 4 0 0 4 4 4 0 Nucleoplasmin PBP1_TM PF14812.1 OAJ28433.1 - 1.4 9.2 9.0 8.7 6.7 1.7 3.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mg_trans_NIPA PF05653.9 OAJ28434.1 - 1.7e-27 96.1 7.6 8.6e-15 54.4 2.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Tetraspannin PF00335.15 OAJ28434.1 - 0.062 12.5 10.6 2.1 7.5 0.1 2.9 2 1 1 3 3 3 0 Tetraspanin family Neurensin PF14927.1 OAJ28434.1 - 1.2 8.5 3.9 8.5 5.7 0.2 2.6 2 0 0 2 2 2 0 Neurensin MFS_1 PF07690.11 OAJ28436.1 - 6.5e-42 143.5 26.2 6.5e-42 143.5 18.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Chitin_synth_2 PF03142.10 OAJ28436.1 - 0.043 12.1 0.2 0.07 11.5 0.1 1.2 1 0 0 1 1 1 0 Chitin synthase Rdx PF10262.4 OAJ28437.1 - 1.7e-20 72.7 0.0 3.8e-20 71.6 0.0 1.6 1 1 0 1 1 1 1 Rdx family Abhydrolase_6 PF12697.2 OAJ28438.1 - 1.9e-18 67.1 0.2 3.4e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ28438.1 - 3e-10 40.0 0.0 6.2e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ28438.1 - 5.5e-06 26.1 0.4 1e-05 25.2 0.3 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 OAJ28438.1 - 0.0001 21.9 0.1 0.00084 18.9 0.2 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ28439.1 - 1.2e-16 61.3 0.1 2.1e-16 60.4 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ28439.1 - 1.1e-15 57.6 0.0 2.1e-15 56.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ28439.1 - 4.7e-12 45.6 0.1 9.7e-12 44.5 0.1 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 OAJ28439.1 - 7.1e-06 25.7 1.1 0.0012 18.4 0.4 3.3 3 1 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 OAJ28439.1 - 1.6e-05 24.4 1.0 0.00099 18.6 0.0 2.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 OAJ28439.1 - 0.016 14.6 0.1 0.032 13.6 0.0 1.6 1 1 0 1 1 1 0 Putative esterase SH3_9 PF14604.1 OAJ28440.1 - 8.9e-06 25.1 0.0 2.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ28440.1 - 0.0001 21.7 0.0 0.00034 20.0 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 OAJ28440.1 - 0.00034 19.9 0.0 0.63 9.4 0.0 2.5 2 0 0 2 2 2 2 SH3 domain MFS_1 PF07690.11 OAJ28441.1 - 5.5e-36 124.0 23.5 1.7e-35 122.4 16.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DNA_pol_viral_C PF00336.13 OAJ28443.1 - 0.031 13.5 0.0 0.069 12.4 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain RVT_3 PF13456.1 OAJ28443.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase-like PepSY_TM_2 PF13703.1 OAJ28444.1 - 0.003 17.6 1.2 0.003 17.6 0.9 2.7 3 0 0 3 3 3 1 PepSY-associated TM helix RFC1 PF08519.7 OAJ28444.1 - 0.093 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain Mito_carr PF00153.22 OAJ28445.1 - 2.8e-54 180.7 9.1 2.5e-18 65.5 0.1 4.6 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF2423 PF10338.4 OAJ28446.1 - 5.2e-09 35.9 6.0 5.2e-09 35.9 4.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) CDC45 PF02724.9 OAJ28446.1 - 1.5 6.7 4.9 1.6 6.6 3.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DAO PF01266.19 OAJ28447.1 - 1e-36 126.6 0.1 1.3e-36 126.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAJ28447.1 - 4.8e-06 26.4 0.6 0.0016 18.2 0.0 2.4 1 1 1 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAJ28447.1 - 0.00071 19.5 0.2 0.0021 18.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAJ28447.1 - 0.0039 17.2 0.0 0.073 13.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ28447.1 - 0.066 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltrans_RNA PF04452.9 OAJ28447.1 - 0.092 11.8 0.1 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase WD40 PF00400.27 OAJ28448.1 - 1.6e-36 122.8 27.2 3.5e-09 36.2 0.3 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat Hira PF07569.6 OAJ28448.1 - 7.5e-32 110.3 0.0 1.4e-18 66.9 0.0 2.2 2 0 0 2 2 2 2 TUP1-like enhancer of split HIRA_B PF09453.5 OAJ28448.1 - 0.002 17.6 0.4 0.002 17.6 0.3 1.9 2 0 0 2 2 2 1 HIRA B motif Paramyxo_ncap PF00973.14 OAJ28451.1 - 0.25 9.9 5.4 0.27 9.9 3.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Vfa1 PF08432.5 OAJ28451.1 - 0.28 11.2 9.7 0.36 10.8 6.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF501 PF04417.7 OAJ28451.1 - 2.5 7.9 9.9 0.091 12.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF501) CDC27 PF09507.5 OAJ28451.1 - 3.1 6.9 18.0 4 6.5 12.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Herpes_DNAp_acc PF04929.7 OAJ28451.1 - 3.4 6.5 6.1 4.5 6.1 4.2 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Ycf1 PF05758.7 OAJ28451.1 - 4.2 4.9 5.4 4.3 4.9 3.8 1.0 1 0 0 1 1 1 0 Ycf1 IQ PF00612.22 OAJ28452.1 - 0.001 18.5 0.2 0.0023 17.4 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Ank_5 PF13857.1 OAJ28453.1 - 1.7e-11 43.9 3.8 0.0022 18.1 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ28453.1 - 5.1e-10 38.6 0.3 0.0065 16.6 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 OAJ28453.1 - 5.5e-10 39.4 0.1 0.002 18.4 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ28453.1 - 2e-07 31.3 0.6 0.07 13.6 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 OAJ28453.1 - 2.3e-06 27.1 10.4 0.0066 16.2 0.1 4.1 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.8 OAJ28453.1 - 0.00052 19.6 0.0 0.0018 17.8 0.0 1.8 1 1 0 1 1 1 1 KilA-N domain MitMem_reg PF13012.1 OAJ28453.1 - 0.057 13.5 0.7 0.11 12.6 0.5 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function FAD_binding_6 PF00970.19 OAJ28455.1 - 5e-31 106.7 0.0 8.2e-31 106.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 OAJ28455.1 - 1.8e-28 99.2 0.0 3.2e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 OAJ28455.1 - 2.3e-06 27.6 0.0 0.00016 21.6 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF1761 PF08570.5 OAJ28455.1 - 0.036 14.0 0.8 0.054 13.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) FAD_binding_9 PF08021.6 OAJ28455.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain SET PF00856.23 OAJ28456.1 - 6.1e-24 85.1 0.4 2.8e-23 83.0 0.0 2.2 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.11 OAJ28456.1 - 6.6e-15 55.2 10.4 6.6e-15 55.2 7.2 1.8 2 0 0 2 2 2 1 Pre-SET motif CDC45 PF02724.9 OAJ28456.1 - 6.5 4.6 7.1 12 3.7 4.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_3 PF01596.12 OAJ28457.1 - 1.6e-52 177.5 0.0 2.2e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 OAJ28457.1 - 3.3e-12 47.1 0.0 5.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ28457.1 - 2.8e-07 30.5 0.0 5.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ28457.1 - 0.0011 19.5 0.0 0.0021 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 OAJ28457.1 - 0.044 13.3 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Aldo_ket_red PF00248.16 OAJ28458.1 - 2.3e-63 213.6 0.0 2.9e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.23 OAJ28459.1 - 1.4e-28 99.4 0.0 1e-27 96.6 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 OAJ28459.1 - 5e-24 84.5 0.0 9.7e-24 83.6 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 OAJ28459.1 - 1.4e-09 38.0 0.1 2.6e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 OAJ28459.1 - 1.3e-07 31.2 0.0 2.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 OAJ28459.1 - 0.0038 16.9 0.5 0.042 13.5 0.4 2.4 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 OAJ28459.1 - 0.017 15.0 1.1 0.15 11.9 0.8 2.4 1 1 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 OAJ28459.1 - 0.15 12.3 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 OAJ28459.1 - 0.28 10.0 0.0 0.5 9.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CAP PF00188.21 OAJ28460.1 - 4.4e-24 85.3 2.8 7e-24 84.6 1.9 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family BUD22 PF09073.5 OAJ28461.1 - 2.7e-44 151.9 41.3 1.9e-43 149.1 28.6 2.3 1 1 0 1 1 1 1 BUD22 RIO1 PF01163.17 OAJ28462.1 - 9.2e-64 214.2 0.7 9.2e-64 214.2 0.5 2.4 2 1 0 2 2 2 1 RIO1 family SDA1 PF05285.7 OAJ28462.1 - 0.58 9.3 30.1 0.22 10.7 11.6 2.4 2 0 0 2 2 2 0 SDA1 Clathrin_lg_ch PF01086.12 OAJ28463.1 - 2.9e-32 112.3 16.6 9.8e-29 100.8 11.5 2.3 1 1 0 1 1 1 1 Clathrin light chain UCH PF00443.24 OAJ28464.1 - 3.5e-52 177.1 0.0 5.3e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ28464.1 - 4e-26 92.1 0.0 7.4e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PTPlike_phytase PF14566.1 OAJ28465.1 - 7e-109 360.4 0.0 2.8e-40 137.7 0.0 3.6 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.15 OAJ28465.1 - 0.00099 18.6 0.0 2.2 7.8 0.0 3.3 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain TFIIE-A_C-term PF11521.3 OAJ28465.1 - 0.0013 18.6 0.0 1.3 8.9 0.0 3.7 3 0 0 3 3 3 1 C-terminal general transcription factor TFIIE alpha Y_phosphatase PF00102.22 OAJ28465.1 - 0.036 13.4 0.3 23 4.2 0.0 3.2 3 0 0 3 3 3 0 Protein-tyrosine phosphatase Acyl-thio_N PF12590.3 OAJ28466.1 - 0.00071 20.0 3.8 0.0013 19.2 2.6 1.4 1 0 0 1 1 1 1 Acyl-ATP thioesterase SR-25 PF10500.4 OAJ28466.1 - 0.0022 17.5 6.9 0.0029 17.1 4.8 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Saccharop_dh_N PF04455.7 OAJ28466.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region PGM_PMM_I PF02878.11 OAJ28468.1 - 3.3e-38 130.2 0.3 5.6e-38 129.5 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 OAJ28468.1 - 4.8e-23 81.4 0.1 1.6e-22 79.7 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 OAJ28468.1 - 8.9e-09 35.3 0.0 2e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 OAJ28468.1 - 1.8e-07 31.0 0.1 8.1e-07 28.9 0.0 2.2 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain SR-25 PF10500.4 OAJ28468.1 - 1.4 8.3 11.6 2.6 7.4 8.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein dCMP_cyt_deam_1 PF00383.17 OAJ28469.1 - 1.1e-19 69.9 0.0 1.9e-19 69.1 0.0 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 OAJ28469.1 - 2e-06 27.6 0.0 3.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Bd3614-like deaminase RimK PF08443.6 OAJ28469.1 - 0.086 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain PNRC PF15365.1 OAJ28469.1 - 0.58 10.2 3.9 1.3 9.1 2.7 1.6 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator EMP24_GP25L PF01105.19 OAJ28471.1 - 2.5e-34 118.5 0.1 3.2e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GRAM PF02893.15 OAJ28472.1 - 1.6e-19 69.1 0.1 1.6e-18 65.9 0.0 2.3 2 0 0 2 2 2 1 GRAM domain DUF3262 PF11660.3 OAJ28472.1 - 0.32 11.1 1.6 0.75 9.9 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) MULE PF10551.4 OAJ28473.1 - 2.9e-18 65.8 0.0 6.6e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.10 OAJ28473.1 - 1.4e-09 37.3 0.0 3.5e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.13 OAJ28473.1 - 1.1e-06 27.5 0.0 1.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family PhyH PF05721.8 OAJ28475.1 - 3.6e-08 33.7 0.0 1.3e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1325 PF07039.6 OAJ28476.1 - 1.3e-28 99.1 0.0 1.9e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain GvpG PF05120.7 OAJ28476.1 - 0.73 9.6 4.6 15 5.4 0.1 3.5 4 0 0 4 4 4 0 Gas vesicle protein G KH_3 PF13014.1 OAJ28477.1 - 2.2e-05 23.9 0.3 3.7e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 KH domain KH_1 PF00013.24 OAJ28477.1 - 2.3e-05 23.9 0.3 3.3e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 KH domain DHHA1 PF02272.14 OAJ28477.1 - 0.062 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 DHHA1 domain TPR_2 PF07719.12 OAJ28478.1 - 0.00043 20.0 0.2 5.3 7.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ28478.1 - 0.00052 19.9 2.8 0.0032 17.3 0.1 3.3 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ28478.1 - 0.0037 17.1 10.0 0.026 14.4 0.3 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat RHH_4 PF13467.1 OAJ28478.1 - 0.018 14.9 0.3 0.086 12.7 0.1 2.4 2 1 0 2 2 2 0 Ribbon-helix-helix domain TPR_11 PF13414.1 OAJ28478.1 - 0.024 14.2 0.5 0.18 11.4 0.1 2.6 3 1 0 3 3 3 0 TPR repeat Muted PF14942.1 OAJ28478.1 - 0.1 12.4 2.3 0.12 12.2 0.8 1.8 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Apc5 PF12862.2 OAJ28478.1 - 0.11 12.3 4.0 8.1 6.3 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 Toxin_39 PF15500.1 OAJ28478.1 - 0.54 10.4 2.2 2.2 8.4 0.3 2.3 2 0 0 2 2 2 0 Putative RNase-like toxin TPR_16 PF13432.1 OAJ28478.1 - 1.1 10.0 5.1 7.9 7.2 0.1 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF2730 PF10805.3 OAJ28479.1 - 0.069 12.8 0.8 0.13 12.0 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Cofilin_ADF PF00241.15 OAJ28480.1 - 3.7e-41 139.9 0.2 4.2e-41 139.8 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CBM_4_9 PF02018.12 OAJ28480.1 - 0.063 13.2 0.0 0.087 12.8 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain LRR_6 PF13516.1 OAJ28481.1 - 1.6e-12 46.0 26.9 0.08 13.0 0.0 10.9 10 1 0 10 10 10 5 Leucine Rich repeat LRR_4 PF12799.2 OAJ28481.1 - 3.3e-05 23.4 24.7 0.00072 19.1 0.2 6.8 3 2 6 9 9 9 4 Leucine Rich repeats (2 copies) GAT PF03127.9 OAJ28481.1 - 9e-05 22.3 0.0 0.001 19.0 0.0 2.6 1 1 0 1 1 1 1 GAT domain LRR_1 PF00560.28 OAJ28481.1 - 0.0015 18.2 19.3 15 6.0 0.1 8.8 10 0 0 10 10 10 3 Leucine Rich Repeat LRR_8 PF13855.1 OAJ28481.1 - 0.32 10.7 20.9 0.37 10.5 1.1 5.6 4 2 2 6 6 6 0 Leucine rich repeat MOSC_N PF03476.11 OAJ28483.1 - 1.9e-20 72.7 0.0 2.9e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 OAJ28483.1 - 1.4e-10 40.7 1.8 6.2e-05 22.4 0.0 2.9 2 1 0 2 2 2 2 MOSC domain HTH_28 PF13518.1 OAJ28485.1 - 0.0043 17.0 0.0 0.027 14.4 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 OAJ28485.1 - 0.066 12.8 0.2 0.38 10.4 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Abhydrolase_5 PF12695.2 OAJ28486.1 - 0.00027 20.6 0.0 0.0015 18.2 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 OAJ28486.1 - 0.0003 20.3 0.0 0.00061 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 OAJ28486.1 - 0.0079 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ28486.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1421 PF07223.6 OAJ28486.1 - 5 6.8 6.7 5.4 6.6 3.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1421) PAT1 PF09770.4 OAJ28487.1 - 8.1 4.5 23.9 8.9 4.4 16.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PCI_Csn8 PF10075.4 OAJ28488.1 - 1.4e-33 115.7 0.0 1.9e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 OAJ28488.1 - 3.1e-30 105.2 0.0 3.9e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Abhydrolase_3 PF07859.8 OAJ28489.1 - 2.1e-15 56.8 0.0 4.6e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ28489.1 - 3.9e-09 36.4 0.0 1.2e-08 34.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ28489.1 - 9.3e-07 28.2 0.0 2e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.23 OAJ28489.1 - 0.011 14.4 0.0 0.019 13.6 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family DEC-1_N PF04625.8 OAJ28489.1 - 2.3 6.7 6.9 3.5 6.2 4.8 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RTA1 PF04479.8 OAJ28490.1 - 5.2e-21 75.1 6.2 5.2e-21 75.1 4.3 2.0 2 1 0 2 2 2 1 RTA1 like protein Cation_ATPase_C PF00689.16 OAJ28490.1 - 0.0071 15.8 8.1 0.11 12.0 5.6 2.2 1 1 0 1 1 1 1 Cation transporting ATPase, C-terminus ABC2_membrane_5 PF13346.1 OAJ28490.1 - 0.33 10.2 10.7 3.2 6.9 0.2 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein RRN3 PF05327.6 OAJ28492.1 - 9.4e-135 449.8 0.0 7.4e-131 437.0 0.0 2.9 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 OAJ28492.1 - 0.035 12.6 15.7 0.083 11.3 10.9 1.5 1 0 0 1 1 1 0 Daxx Family Apt1 PF10351.4 OAJ28492.1 - 5.8 5.6 5.0 14 4.4 3.5 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain SET PF00856.23 OAJ28493.1 - 0.0012 19.1 0.0 0.0049 17.1 0.0 1.8 1 1 0 1 1 1 1 SET domain Rhodanese PF00581.15 OAJ28494.1 - 2.9e-16 59.8 0.0 4.9e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain P19Arf_N PF07392.7 OAJ28494.1 - 0.06 13.5 0.4 0.19 11.8 0.3 1.9 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus ING PF12998.2 OAJ28495.1 - 1.1e-13 51.3 0.4 2e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 OAJ28495.1 - 2.6e-08 33.4 10.9 4.3e-08 32.7 7.6 1.4 1 0 0 1 1 1 1 PHD-finger Phosphoesterase PF04185.9 OAJ28496.1 - 5.6e-29 101.4 3.1 1e-28 100.6 2.1 1.3 1 1 0 1 1 1 1 Phosphoesterase family Calcipressin PF04847.7 OAJ28496.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Calcipressin Histone PF00125.19 OAJ28497.1 - 1.3e-25 89.2 0.0 1.8e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAJ28497.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAJ28498.1 - 1.4e-22 79.5 0.4 1.9e-22 79.1 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAJ28498.1 - 4.5e-07 29.8 0.1 8.5e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 OAJ28498.1 - 0.00037 20.7 0.0 0.00058 20.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 OAJ28498.1 - 0.034 14.6 0.3 0.045 14.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.8 OAJ28498.1 - 0.042 13.2 0.1 0.074 12.5 0.1 1.4 1 1 0 1 1 1 0 Replication protein C N-terminal domain AIRS PF00586.19 OAJ28499.1 - 8.7e-16 57.9 0.0 1.6e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Trehalase PF01204.13 OAJ28500.1 - 1.1e-170 568.7 0.2 1.4e-170 568.3 0.1 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 OAJ28500.1 - 6.3e-15 54.1 0.0 1e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Cpn60_TCP1 PF00118.19 OAJ28501.1 - 3.3e-143 477.8 0.3 3.8e-143 477.6 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.16 OAJ28501.1 - 0.086 12.6 0.4 1 9.1 0.1 2.6 2 0 0 2 2 2 0 Resolvase, N terminal domain Enolase_N PF03952.11 OAJ28501.1 - 0.52 10.2 3.9 32 4.4 0.1 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain GSHPx PF00255.14 OAJ28502.1 - 3.5e-31 106.7 0.1 4.5e-31 106.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.5 OAJ28502.1 - 1.7e-05 24.3 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAJ28502.1 - 0.00016 21.3 0.1 0.00046 19.8 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.1 OAJ28502.1 - 0.081 13.0 0.1 0.097 12.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) Cys_rich_CWC PF14375.1 OAJ28503.1 - 1.6 8.6 7.1 0.65 9.9 3.1 1.7 2 0 0 2 2 2 0 Cysteine-rich CWC GSH_synth_ATP PF03917.12 OAJ28504.1 - 3.3e-78 262.8 0.0 7.7e-38 130.0 0.0 4.3 2 2 0 2 2 2 2 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 OAJ28504.1 - 1.6e-29 102.1 0.0 3e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Collagen PF01391.13 OAJ28505.1 - 4.3e-23 80.6 83.5 3.4e+02 0.8 57.9 3.0 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Ribosomal_S8e PF01201.17 OAJ28507.1 - 8.8e-38 129.4 9.8 6.9e-37 126.5 6.8 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e Mer2 PF09074.5 OAJ28507.1 - 0.014 15.3 0.0 0.014 15.3 0.0 1.9 2 0 0 2 2 2 0 Mer2 Methyltransf_16 PF10294.4 OAJ28508.1 - 2.6e-12 46.5 0.2 2.8e-10 39.9 0.2 2.9 2 1 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 OAJ28508.1 - 0.011 15.1 0.0 0.25 10.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_26 PF13659.1 OAJ28508.1 - 0.022 14.7 0.0 0.043 13.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 OAJ28508.1 - 0.07 12.6 0.1 0.82 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.20 OAJ28509.1 - 4.9e-36 124.2 0.0 6.4e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28509.1 - 1.4e-12 47.2 0.0 1.9e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Sporozoite_P67 PF05642.6 OAJ28509.1 - 0.97 7.2 13.8 1.3 6.8 9.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TB2_DP1_HVA22 PF03134.14 OAJ28510.1 - 8.1e-29 99.2 6.6 1.1e-28 98.7 4.6 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family GrpE PF01025.14 OAJ28511.1 - 1.3e-42 145.1 0.1 1.9e-42 144.6 0.1 1.2 1 0 0 1 1 1 1 GrpE Kdo PF06293.9 OAJ28512.1 - 4.3e-05 22.6 0.0 0.001 18.1 0.0 2.4 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 OAJ28512.1 - 0.00014 21.1 0.0 0.00022 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 OAJ28512.1 - 0.00059 19.6 0.0 0.0084 15.8 0.0 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 OAJ28512.1 - 0.032 13.3 0.0 4.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Ecdysteroid kinase RIO1 PF01163.17 OAJ28512.1 - 0.053 12.8 0.0 3.8 6.7 0.0 2.2 2 0 0 2 2 2 0 RIO1 family DNA_topoisoIV PF00521.15 OAJ28513.1 - 7.1e-127 423.7 0.1 2.4e-126 422.0 0.0 1.9 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 OAJ28513.1 - 6e-34 116.7 0.5 1.5e-33 115.4 0.3 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 OAJ28513.1 - 2.4e-14 53.1 0.0 2.9e-13 49.6 0.0 2.8 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 OAJ28513.1 - 1.5e-07 31.1 0.0 4.5e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC27 PF09507.5 OAJ28513.1 - 3.2 6.8 33.8 0.068 12.3 15.6 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 RhoGEF PF00621.15 OAJ28514.1 - 1.7e-36 125.8 0.0 3.4e-36 124.7 0.0 1.5 1 1 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 OAJ28514.1 - 6.3e-18 64.4 9.3 1.2e-17 63.5 6.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 OAJ28514.1 - 2.7e-09 37.1 0.0 5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 PH domain TPP1 PF10341.4 OAJ28515.1 - 2.5e-05 24.1 0.0 4.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD Sel1 PF08238.7 OAJ28516.1 - 4.7e-16 58.8 19.6 3.5e-06 27.4 0.2 4.5 4 0 0 4 4 4 3 Sel1 repeat TPR_11 PF13414.1 OAJ28516.1 - 0.1 12.2 5.1 1.1 9.0 0.0 3.3 3 1 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 OAJ28516.1 - 4 7.5 5.8 6.2 6.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.26 OAJ28517.1 - 1.3e-28 98.7 1.0 5.3e-16 58.4 1.0 3.8 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ28517.1 - 1.3e-24 86.0 0.1 3.9e-16 58.9 0.1 3.9 1 1 2 3 3 3 3 Myb-like DNA-binding domain PSP1 PF04468.7 OAJ28518.1 - 8.3e-32 109.0 0.1 1.3e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DNA_primase_lrg PF04104.9 OAJ28519.1 - 2.1e-78 263.2 0.0 2.5e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit KH_1 PF00013.24 OAJ28520.1 - 2.8e-05 23.6 0.1 7.9e-05 22.2 0.1 1.7 2 0 0 2 2 2 1 KH domain RAP1 PF07218.6 OAJ28520.1 - 0.0015 16.6 1.4 0.0022 16.1 1.0 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) DEAD PF00270.24 OAJ28521.1 - 1.5e-41 141.7 0.0 3.6e-41 140.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ28521.1 - 2.9e-26 91.1 0.0 2.4e-25 88.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Borrelia_P83 PF05262.6 OAJ28521.1 - 0.036 12.3 13.4 0.045 12.0 9.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC27 PF09507.5 OAJ28521.1 - 2.5 7.2 26.1 4 6.5 18.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 F-box-like PF12937.2 OAJ28522.1 - 0.00015 21.3 0.2 0.00032 20.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 OAJ28522.1 - 0.055 13.2 0.3 0.4 10.4 0.3 2.2 1 1 1 2 2 2 0 Leucine rich repeat RVT_1 PF00078.22 OAJ28524.1 - 1.3e-26 93.3 0.0 6.4e-26 91.0 0.0 2.1 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) WES_acyltransf PF03007.11 OAJ28525.1 - 9.2e-18 64.7 0.0 2e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF566 PF04484.7 OAJ28525.1 - 3.3 7.1 7.4 6.3 6.2 5.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) Phage_integrase PF00589.17 OAJ28527.1 - 3.9e-05 23.3 0.0 5.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF4431 PF14485.1 OAJ28527.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) ERCC4 PF02732.10 OAJ28528.1 - 5.6e-26 91.0 0.0 9.3e-26 90.2 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 OAJ28528.1 - 0.0024 17.9 0.0 0.0064 16.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain Aldo_ket_red PF00248.16 OAJ28530.1 - 1e-29 103.2 0.0 3.6e-28 98.2 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family Dec-1 PF04624.9 OAJ28531.1 - 0.08 12.5 1.2 0.08 12.5 0.8 2.3 2 0 0 2 2 2 0 Dec-1 repeat Hrs_helical PF12210.3 OAJ28531.1 - 0.2 11.8 1.9 0.29 11.4 1.3 1.3 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Far-17a_AIG1 PF04750.9 OAJ28532.1 - 9.5e-42 142.4 6.1 1.2e-41 142.1 4.2 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Inositol_P PF00459.20 OAJ28533.1 - 1.1e-52 178.9 0.6 8e-52 176.2 0.4 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family AAA_33 PF13671.1 OAJ28534.1 - 5.8e-20 71.6 1.2 4.4e-19 68.7 0.9 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAJ28534.1 - 1e-08 34.5 0.0 0.00055 19.0 0.0 2.2 1 1 1 2 2 2 2 Zeta toxin tRNA_lig_kinase PF08303.6 OAJ28534.1 - 4.7e-08 33.0 0.1 7e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 tRNA ligase kinase domain KTI12 PF08433.5 OAJ28534.1 - 5.6e-08 32.3 1.7 3.7e-06 26.3 1.2 2.1 1 1 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.7 OAJ28534.1 - 0.00074 19.1 0.1 0.11 12.1 0.0 2.2 1 1 1 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.1 OAJ28534.1 - 0.00081 19.5 0.0 0.0018 18.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ28534.1 - 0.0012 19.1 2.0 0.11 12.8 1.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ28534.1 - 0.02 15.7 0.0 0.037 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 OAJ28534.1 - 0.034 12.8 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.1 OAJ28534.1 - 0.037 14.0 0.0 0.072 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 OAJ28534.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.9 1 1 0 1 1 1 0 Part of AAA domain APS_kinase PF01583.15 OAJ28534.1 - 0.051 13.2 0.3 0.22 11.1 0.0 1.9 1 1 1 2 2 2 0 Adenylylsulphate kinase SKI PF01202.17 OAJ28534.1 - 0.065 13.0 0.4 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase Thymidylate_kin PF02223.12 OAJ28534.1 - 0.11 11.8 0.0 4.1 6.7 0.1 2.5 2 1 0 2 2 2 0 Thymidylate kinase C1-set PF07654.10 OAJ28534.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin C1-set domain Exo5 PF09810.4 OAJ28535.1 - 9.8e-51 172.8 0.0 2.3e-44 151.9 0.0 3.3 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease DUF2865 PF11064.3 OAJ28537.1 - 0.098 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2865) Peptidase_M76 PF09768.4 OAJ28538.1 - 1.4e-48 164.6 0.0 2.2e-48 163.9 0.0 1.3 1 1 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 OAJ28538.1 - 0.0028 17.3 0.1 0.015 14.9 0.0 1.9 2 0 0 2 2 2 1 SprT-like family Hex_IIIa PF02455.11 OAJ28539.1 - 0.053 12.2 1.7 0.062 11.9 1.2 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) TFIIA PF03153.8 OAJ28539.1 - 4.4 7.0 10.8 6 6.6 7.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec1 PF00995.18 OAJ28540.1 - 1.6e-148 495.8 0.0 1.8e-148 495.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family IFT20 PF14931.1 OAJ28540.1 - 0.12 12.2 0.4 0.23 11.3 0.3 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 UPF0020 PF01170.13 OAJ28541.1 - 3.4e-13 49.5 0.0 1.7e-12 47.2 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 OAJ28541.1 - 1.3e-10 41.2 0.0 2.8e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 OAJ28541.1 - 7.5e-06 25.5 0.0 0.00013 21.5 0.0 2.6 2 1 0 2 2 2 1 DNA methylase N6_Mtase PF02384.11 OAJ28541.1 - 0.0012 17.9 0.0 0.0041 16.2 0.0 1.8 1 1 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.10 OAJ28541.1 - 0.008 15.6 0.0 0.027 13.9 0.0 1.8 2 0 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase Met_10 PF02475.11 OAJ28541.1 - 0.028 14.0 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein RRM_1 PF00076.17 OAJ28542.1 - 1.4e-34 117.5 0.1 2.8e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ28542.1 - 5.3e-32 109.6 0.1 1.4e-15 57.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ28542.1 - 2.5e-10 40.0 0.1 0.00014 21.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAJ28542.1 - 0.015 15.0 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 OAJ28542.1 - 0.016 15.0 0.0 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif HA2 PF04408.18 OAJ28544.1 - 2.1e-24 85.4 0.1 1.2e-23 83.0 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 OAJ28544.1 - 3.3e-24 84.9 0.0 8.9e-24 83.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 OAJ28544.1 - 2.8e-14 52.7 0.0 6.6e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ28544.1 - 1.7e-06 27.6 0.0 4.5e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ28544.1 - 0.00074 19.6 0.0 0.0025 17.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 OAJ28544.1 - 0.0048 15.8 0.0 0.0089 14.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 OAJ28544.1 - 0.01 15.2 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 OAJ28544.1 - 0.012 15.5 1.2 0.86 9.5 0.0 3.4 2 1 0 2 2 2 0 AAA domain PWI PF01480.12 OAJ28544.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 PWI domain ResIII PF04851.10 OAJ28544.1 - 0.028 14.2 0.0 7.4 6.3 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 OAJ28544.1 - 0.065 12.9 0.0 0.24 11.1 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 OAJ28544.1 - 0.14 12.4 1.0 0.45 10.8 0.1 2.3 1 1 1 2 2 2 0 ABC transporter UPF0079 PF02367.12 OAJ28544.1 - 0.15 11.7 0.0 0.42 10.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 OAJ28544.1 - 1.5 9.1 0.0 1.5 9.1 0.0 2.9 2 1 0 2 2 1 0 AAA domain Metallophos PF00149.23 OAJ28545.1 - 5.1e-43 146.8 0.9 6.3e-43 146.4 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rtf2 PF04641.7 OAJ28548.1 - 1.9e-54 184.6 0.0 5.4e-54 183.1 0.0 1.8 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 OAJ28548.1 - 0.069 12.6 0.0 1.8 8.1 0.0 2.7 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit tRNA_m1G_MT PF01746.16 OAJ28549.1 - 2.1e-20 73.1 0.1 9.7e-16 57.8 0.1 3.2 2 1 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase GCV_H PF01597.14 OAJ28550.1 - 1.5e-40 137.6 1.0 1.8e-40 137.4 0.7 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 OAJ28550.1 - 0.0012 18.4 0.6 0.0025 17.4 0.3 1.6 2 0 0 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.1 OAJ28550.1 - 0.009 15.7 0.1 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain TfoX_C PF04994.8 OAJ28550.1 - 0.12 12.2 0.0 0.76 9.7 0.0 2.1 2 1 0 2 2 2 0 TfoX C-terminal domain Syja_N PF02383.13 OAJ28551.1 - 8.4e-90 300.7 0.0 1.1e-89 300.3 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain zf-Tim10_DDP PF02953.10 OAJ28552.1 - 3.3e-18 64.7 4.5 3.3e-18 64.7 3.1 1.5 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Ssu72 PF04722.8 OAJ28552.1 - 0.051 12.8 0.1 0.058 12.7 0.1 1.1 1 0 0 1 1 1 0 Ssu72-like protein Mmp37 PF09139.6 OAJ28552.1 - 0.079 11.9 0.1 0.086 11.8 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 FA_hydroxylase PF04116.8 OAJ28553.1 - 2.6e-12 47.1 11.0 2.6e-12 47.1 7.6 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily YL1 PF05764.8 OAJ28554.1 - 0.0037 16.9 8.7 0.0037 16.9 6.0 3.2 3 0 0 3 3 3 2 YL1 nuclear protein Stonin2_N PF12016.3 OAJ28555.1 - 0.073 12.1 2.2 0.081 12.0 1.5 1.0 1 0 0 1 1 1 0 Stonin 2 Smr PF01713.16 OAJ28556.1 - 4.5e-10 39.5 0.0 3.9e-09 36.5 0.0 2.7 2 1 0 2 2 2 1 Smr domain DUF3535 PF12054.3 OAJ28557.1 - 8.2e-112 374.0 0.0 1.7e-110 369.7 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 OAJ28557.1 - 1.6e-70 237.2 0.0 2.4e-70 236.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 OAJ28557.1 - 3.5e-13 48.4 28.2 0.031 14.3 0.0 11.2 13 0 0 13 13 13 3 HEAT repeat Helicase_C PF00271.26 OAJ28557.1 - 6.2e-12 45.2 0.0 1.6e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 OAJ28557.1 - 0.0048 17.1 0.2 0.0048 17.1 0.2 8.9 9 2 0 9 9 9 1 HEAT repeats HEAT_EZ PF13513.1 OAJ28557.1 - 0.016 15.6 35.2 12 6.5 0.1 11.5 11 1 1 12 12 12 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 OAJ28557.1 - 0.017 15.5 0.0 0.2 12.0 0.0 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 OAJ28557.1 - 0.022 14.1 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 0 CLASP N terminal HDA2-3 PF11496.3 OAJ28557.1 - 0.078 11.7 0.0 0.19 10.4 0.0 1.5 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 RIX1 PF08167.7 OAJ28557.1 - 0.095 12.3 0.1 4.5 6.9 0.0 2.7 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Arginosuc_synth PF00764.14 OAJ28558.1 - 1.3e-155 518.2 0.0 1.6e-155 517.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 OAJ28558.1 - 0.00025 20.3 0.0 0.00039 19.7 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 OAJ28558.1 - 0.002 17.6 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase LolA PF03548.10 OAJ28558.1 - 0.028 14.0 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA tRNA_Me_trans PF03054.11 OAJ28558.1 - 0.07 11.6 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase RNA_POL_M_15KD PF02150.11 OAJ28559.1 - 6.3e-13 48.1 7.4 1.2e-12 47.3 2.8 2.1 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 OAJ28559.1 - 2.4e-06 27.0 5.6 0.00044 19.8 0.1 3.0 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) GFA PF04828.9 OAJ28559.1 - 3.1e-05 23.8 1.0 0.0051 16.7 0.1 2.1 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 OAJ28559.1 - 0.00035 20.3 1.8 0.17 11.7 0.3 2.3 2 0 0 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.1 OAJ28559.1 - 0.0059 15.7 6.2 0.1 11.8 0.1 3.1 3 0 0 3 3 3 1 zinc-ribbon domain Zn-ribbon_8 PF09723.5 OAJ28559.1 - 0.0064 16.4 3.6 1.6 8.7 0.1 3.0 3 0 0 3 3 3 1 Zinc ribbon domain Lar_restr_allev PF14354.1 OAJ28559.1 - 0.008 16.4 1.1 2.8 8.2 0.1 2.2 2 0 0 2 2 2 2 Restriction alleviation protein Lar Elf1 PF05129.8 OAJ28559.1 - 0.021 14.5 1.1 2 8.1 0.3 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C4_Topoisom PF01396.14 OAJ28559.1 - 0.036 13.5 2.8 3.5 7.2 0.7 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Zn_Tnp_IS1595 PF12760.2 OAJ28559.1 - 0.038 13.8 5.5 0.87 9.4 0.1 2.5 3 0 0 3 3 2 0 Transposase zinc-ribbon domain zf-ISL3 PF14690.1 OAJ28559.1 - 0.086 12.8 1.9 0.99 9.4 0.0 2.7 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 OrfB_Zn_ribbon PF07282.6 OAJ28559.1 - 0.13 11.9 1.6 3.9 7.1 0.3 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain C1_4 PF07975.7 OAJ28559.1 - 0.13 12.3 3.6 0.41 10.7 1.0 2.1 2 0 0 2 2 2 0 TFIIH C1-like domain eIF-5_eIF-2B PF01873.12 OAJ28559.1 - 0.2 11.2 2.0 0.44 10.2 0.5 1.9 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Zn_Tnp_IS1 PF03811.8 OAJ28559.1 - 0.21 11.1 0.1 0.21 11.1 0.0 2.5 3 0 0 3 3 3 0 InsA N-terminal domain Rubredoxin PF00301.15 OAJ28559.1 - 0.41 10.5 4.2 4.7 7.1 0.0 2.8 3 0 0 3 3 3 0 Rubredoxin zf-3CxxC PF13695.1 OAJ28559.1 - 0.47 10.7 3.8 1.9 8.7 2.4 2.0 1 1 0 1 1 1 0 Zinc-binding domain HypA PF01155.14 OAJ28559.1 - 0.62 9.7 3.4 2.1 8.0 2.4 1.8 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family TF_Zn_Ribbon PF08271.7 OAJ28559.1 - 0.65 9.3 3.6 3.4 7.0 0.0 2.8 3 0 0 3 3 3 0 TFIIB zinc-binding Prim_Zn_Ribbon PF08273.7 OAJ28559.1 - 0.88 9.6 4.9 1.6 8.8 0.0 2.7 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-nanos PF05741.8 OAJ28559.1 - 1.1 9.2 5.2 3.1 7.8 0.0 2.5 3 0 0 3 3 2 0 Nanos RNA binding domain Rpr2 PF04032.11 OAJ28559.1 - 1.1 9.1 6.2 7.7 6.4 4.3 2.4 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-RING_3 PF14369.1 OAJ28559.1 - 4.7 7.3 6.5 13 5.8 0.4 2.2 2 0 0 2 2 2 0 zinc-finger zf-LITAF-like PF10601.4 OAJ28559.1 - 6.3 6.7 5.7 4.5 7.2 0.0 2.7 2 1 0 3 3 3 0 LITAF-like zinc ribbon domain DUF3716 PF12511.3 OAJ28559.1 - 6.8 6.3 6.6 6.1 6.5 2.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3716) Nudix_N_2 PF14803.1 OAJ28559.1 - 7.7 6.3 7.1 40 4.0 0.1 2.7 2 1 0 2 2 2 0 Nudix N-terminal RecR PF02132.10 OAJ28559.1 - 9.6 5.7 6.9 2.4 7.6 0.2 2.7 3 0 0 3 3 3 0 RecR protein Ribosomal_L31e PF01198.14 OAJ28560.1 - 6.3e-33 112.3 3.0 1.1e-32 111.5 2.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L31e Ldh_1_N PF00056.18 OAJ28562.1 - 7.4e-44 148.9 0.1 1.1e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 OAJ28562.1 - 7.7e-42 142.9 0.0 1.2e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 OAJ28562.1 - 0.0027 16.4 0.0 0.0067 15.1 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 OAJ28562.1 - 0.0074 16.3 0.8 0.026 14.5 0.6 1.9 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 OAJ28562.1 - 0.017 15.4 0.3 0.11 12.7 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 OAJ28562.1 - 0.05 12.6 0.9 0.74 8.8 0.0 2.6 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SAP30_Sin3_bdg PF13867.1 OAJ28564.1 - 9.6e-08 31.7 0.0 1.1e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 CDC45 PF02724.9 OAJ28564.1 - 0.0032 15.5 2.5 0.004 15.2 1.7 1.1 1 0 0 1 1 1 1 CDC45-like protein Sporozoite_P67 PF05642.6 OAJ28564.1 - 0.012 13.4 7.7 0.017 13.0 5.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.7 OAJ28564.1 - 0.032 13.5 3.3 0.041 13.1 2.3 1.3 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 OAJ28564.1 - 0.053 12.0 2.1 0.062 11.7 1.5 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 OAJ28564.1 - 0.094 10.6 6.8 0.11 10.3 4.7 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 OAJ28564.1 - 1.4 8.7 9.6 1.3 8.7 5.4 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Prothymosin PF03247.9 OAJ28564.1 - 1.5 9.0 17.9 0.88 9.7 8.6 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family Sas10 PF09368.5 OAJ28566.1 - 6e-25 87.2 3.0 1.8e-24 85.6 2.1 1.9 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 OAJ28566.1 - 3.7e-09 36.6 0.0 1.4e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Fcf2 PF08698.6 OAJ28567.1 - 5.9e-14 51.8 0.0 3.7e-13 49.3 0.0 2.2 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing DUF2839 PF10999.3 OAJ28568.1 - 0.096 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) AAA_23 PF13476.1 OAJ28569.1 - 3.9e-26 92.6 2.1 3.9e-26 92.6 1.5 8.5 1 1 2 3 3 1 1 AAA domain AAA_21 PF13304.1 OAJ28569.1 - 5.4e-15 56.1 0.6 3.6e-06 27.1 0.4 2.9 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 OAJ28569.1 - 1.3e-10 41.0 0.2 1.3e-09 37.8 0.0 2.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 OAJ28569.1 - 2.9e-09 36.4 0.1 2.9e-09 36.4 0.1 3.2 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 OAJ28569.1 - 2.8e-07 29.9 38.2 0.00032 19.8 4.2 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_13 PF13166.1 OAJ28569.1 - 6.4e-05 21.6 0.1 6.4e-05 21.6 0.1 8.0 3 1 3 7 7 6 4 AAA domain AAA_29 PF13555.1 OAJ28569.1 - 0.00019 20.9 0.0 0.00037 19.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 OAJ28569.1 - 0.0013 19.0 0.0 0.0013 19.0 0.0 7.1 3 2 1 4 4 2 1 ABC transporter AAA_19 PF13245.1 OAJ28569.1 - 0.023 14.4 0.1 0.13 12.0 0.1 2.3 1 0 0 1 1 1 0 Part of AAA domain Miro PF08477.8 OAJ28569.1 - 0.028 14.8 1.2 0.59 10.6 0.0 3.7 3 0 0 3 3 3 0 Miro-like protein DUF1829 PF08862.5 OAJ28569.1 - 0.073 13.3 0.1 0.073 13.3 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function DUF1829 FH2 PF02181.18 OAJ28570.1 - 5.3e-64 216.4 3.7 5.3e-64 216.4 2.5 2.4 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 OAJ28570.1 - 2.9e-45 153.9 2.8 3.1e-45 153.8 0.0 2.6 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 OAJ28570.1 - 6.1e-43 146.5 0.4 5.8e-42 143.3 0.0 2.6 3 0 0 3 3 3 1 Diaphanous FH3 Domain G-gamma PF00631.17 OAJ28570.1 - 1.2 8.9 3.6 1.3 8.8 0.1 2.7 2 0 0 2 2 2 0 GGL domain TPR_11 PF13414.1 OAJ28571.1 - 3.5e-16 58.6 2.2 4.1e-12 45.5 0.3 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 OAJ28571.1 - 6.1e-08 32.0 4.9 0.079 12.9 0.1 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ28571.1 - 3.8e-07 29.4 2.3 0.11 12.1 0.1 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ28571.1 - 0.0035 17.9 3.1 0.0035 17.9 2.2 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat zf-RING_4 PF14570.1 OAJ28571.1 - 0.057 13.0 0.4 0.12 12.0 0.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TPR_12 PF13424.1 OAJ28571.1 - 0.18 11.7 5.1 1.2 9.1 0.2 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat PFK PF00365.15 OAJ28572.1 - 3.4e-165 547.9 4.0 1.3e-97 326.2 0.3 3.2 3 0 0 3 3 3 3 Phosphofructokinase FAM216B PF15107.1 OAJ28572.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 FAM216B protein family Zip PF02535.17 OAJ28573.1 - 9.2e-30 103.7 12.7 9.2e-30 103.7 8.8 4.2 2 2 1 3 3 3 2 ZIP Zinc transporter DUF605 PF04652.11 OAJ28573.1 - 0.0016 17.8 4.5 0.0016 17.8 3.1 2.1 1 1 0 2 2 2 1 Vta1 like PspC PF04024.7 OAJ28573.1 - 0.12 11.8 0.2 9 5.8 0.1 2.6 2 0 0 2 2 2 0 PspC domain ATE_C PF04377.10 OAJ28573.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, C terminus HisG_C PF08029.6 OAJ28574.1 - 0.036 14.0 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 HisG, C-terminal domain YlaH PF14036.1 OAJ28574.1 - 0.044 13.8 0.7 0.044 13.8 0.5 2.1 3 0 0 3 3 3 0 YlaH-like protein PMT_2 PF13231.1 OAJ28574.1 - 2 8.2 10.5 1.9 8.3 3.2 2.4 2 1 1 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DEP PF00610.16 OAJ28575.1 - 8.8e-17 60.6 0.2 3.2e-16 58.8 0.1 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Porin_3 PF01459.17 OAJ28577.1 - 9.1e-61 205.5 0.5 1e-60 205.3 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin Rrp15p PF07890.7 OAJ28578.1 - 9e-27 93.6 0.5 9e-27 93.6 0.4 2.4 2 1 0 2 2 2 1 Rrp15p Daxx PF03344.10 OAJ28578.1 - 0.013 14.0 12.0 0.018 13.5 8.3 1.3 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 OAJ28578.1 - 0.026 12.8 20.6 0.047 12.0 14.3 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YL1 PF05764.8 OAJ28578.1 - 0.34 10.4 22.8 0.92 9.0 15.8 1.7 1 1 0 1 1 1 0 YL1 nuclear protein DUF3295 PF11702.3 OAJ28578.1 - 0.53 9.2 9.5 0.91 8.4 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Ebola_NP PF05505.7 OAJ28578.1 - 0.84 7.6 11.1 1.3 7.0 7.7 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein Med17 PF10156.4 OAJ28578.1 - 1.2 7.2 7.3 5.1 5.2 0.0 2.1 2 0 0 2 2 2 0 Subunit 17 of Mediator complex BUD22 PF09073.5 OAJ28578.1 - 1.7 7.6 25.8 0.35 9.9 12.3 2.2 2 0 0 2 2 2 0 BUD22 CDC45 PF02724.9 OAJ28578.1 - 7.6 4.4 19.6 1.5 6.8 10.6 1.7 2 0 0 2 2 2 0 CDC45-like protein Mpp10 PF04006.7 OAJ28578.1 - 7.9 4.7 20.9 17 3.5 14.5 1.4 1 0 0 1 1 1 0 Mpp10 protein Myc_N PF01056.13 OAJ28578.1 - 9.9 5.2 17.2 1.5e+04 -5.4 11.9 2.5 1 1 0 1 1 0 0 Myc amino-terminal region Pro-kuma_activ PF09286.6 OAJ28579.1 - 3.3e-16 59.6 0.0 6.3e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 OAJ28579.1 - 1e-13 51.0 6.4 1e-13 51.0 4.5 1.6 2 0 0 2 2 2 1 Subtilase family PhoPQ_related PF10142.4 OAJ28579.1 - 0.14 10.5 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein PT PF04886.7 OAJ28580.1 - 0.037 13.3 7.1 1.1 8.5 0.3 4.2 3 1 2 5 5 5 0 PT repeat PTR2 PF00854.16 OAJ28581.1 - 0.1 11.3 1.1 0.13 11.0 0.8 1.1 1 0 0 1 1 1 0 POT family Abhydrolase_5 PF12695.2 OAJ28582.1 - 0.084 12.6 0.0 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ28582.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family WD40 PF00400.27 OAJ28583.1 - 3.7e-05 23.4 4.4 0.00062 19.5 0.2 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat SPX PF03105.14 OAJ28585.1 - 1.7e-07 31.3 0.0 1.7e-07 31.3 0.0 3.1 2 1 0 2 2 2 1 SPX domain Phage_integrase PF00589.17 OAJ28585.1 - 3.2e-07 30.1 0.0 1.2e-05 25.1 0.0 2.7 2 0 0 2 2 2 1 Phage integrase family RVT_3 PF13456.1 OAJ28585.1 - 0.00089 18.9 0.1 0.0026 17.4 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like Glycophorin_A PF01102.13 OAJ28586.1 - 0.00022 20.9 1.0 0.00022 20.9 0.7 2.1 2 1 0 2 2 2 1 Glycophorin A GRA6 PF05084.8 OAJ28586.1 - 0.0027 17.2 2.3 0.0053 16.3 1.6 1.6 1 1 0 1 1 1 1 Granule antigen protein (GRA6) DUF1191 PF06697.7 OAJ28586.1 - 0.0043 15.9 0.0 0.0065 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) TMEM154 PF15102.1 OAJ28586.1 - 0.06 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.15 OAJ28586.1 - 0.11 12.1 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Pex14_N PF04695.8 OAJ28586.1 - 2.2 8.3 7.8 0.17 11.9 1.5 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Alpha_GJ PF03229.8 OAJ28586.1 - 7.9 6.8 20.8 0.056 13.7 5.4 2.5 2 1 0 2 2 2 0 Alphavirus glycoprotein J DUF1517 PF07466.6 OAJ28586.1 - 9.1 5.1 8.7 0.75 8.7 2.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1517) An_peroxidase PF03098.10 OAJ28588.1 - 0.018 13.4 0.0 0.021 13.2 0.0 1.1 1 0 0 1 1 1 0 Animal haem peroxidase Sec23_helical PF04815.10 OAJ28588.1 - 0.059 12.8 0.1 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Sec23/Sec24 helical domain Helicase_C PF00271.26 OAJ28592.1 - 3.3e-07 30.0 0.0 8.4e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ28592.1 - 0.00067 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase p450 PF00067.17 OAJ28594.1 - 5.7e-59 199.8 0.0 1.1e-58 198.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 FTO_CTD PF12934.2 OAJ28594.1 - 0.049 13.2 0.1 0.089 12.3 0.1 1.4 1 0 0 1 1 1 0 FTO C-terminal domain PTPS_related PF10131.4 OAJ28595.1 - 0.023 12.8 0.1 0.033 12.3 0.1 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein TMEM154 PF15102.1 OAJ28597.1 - 0.049 13.3 1.5 0.15 11.7 1.0 1.9 1 0 0 1 1 1 0 TMEM154 protein family Ebp2 PF05890.7 OAJ28600.1 - 2.8e-71 240.0 13.2 2.8e-71 240.0 9.2 2.5 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DUF573 PF04504.9 OAJ28600.1 - 0.047 13.9 1.0 0.13 12.5 0.6 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF573 DUF3295 PF11702.3 OAJ28600.1 - 4.5 6.1 22.9 8.3 5.2 15.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Nipped-B_C PF12830.2 OAJ28602.1 - 1.9e-47 161.3 3.3 3.7e-47 160.3 1.1 2.5 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 OAJ28602.1 - 4.2e-08 32.9 1.1 3.7e-06 26.7 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 OAJ28602.1 - 0.006 16.4 0.4 0.046 13.5 0.1 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 OAJ28602.1 - 0.028 12.7 6.8 1.8 6.8 0.1 3.6 3 2 0 3 3 3 0 Adaptin N terminal region HEAT_EZ PF13513.1 OAJ28602.1 - 0.03 14.7 10.2 2.2 8.8 1.7 5.3 3 1 1 4 4 4 0 HEAT-like repeat EVE PF01878.13 OAJ28603.1 - 5.1e-44 149.7 0.0 8.7e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 EVE domain DUF202 PF02656.10 OAJ28604.1 - 1.4e-06 28.3 10.5 1.1e-05 25.5 4.6 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF202) MCM PF00493.18 OAJ28605.1 - 2.2e-129 431.0 0.0 3.2e-129 430.5 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 OAJ28605.1 - 5.6e-24 84.9 0.0 1.4e-23 83.7 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 OAJ28605.1 - 9.4e-08 31.4 0.0 1.1e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 OAJ28605.1 - 0.0036 16.8 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAJ28605.1 - 0.0056 16.1 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ28605.1 - 0.054 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Peptidase_S26 PF10502.4 OAJ28606.1 - 1.3e-06 27.9 0.0 0.00012 21.5 0.0 3.0 3 1 0 3 3 3 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 OAJ28606.1 - 0.00019 21.0 0.0 0.0007 19.2 0.0 2.0 1 1 0 1 1 1 1 Peptidase S24-like Herpes_capsid PF06112.6 OAJ28606.1 - 0.49 10.4 4.3 0.66 10.0 3.0 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Cut8_C PF08559.5 OAJ28607.1 - 0.034 13.9 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Cut8 six-helix bundle Linker_histone PF00538.14 OAJ28608.1 - 7.7e-12 45.1 0.1 1.5e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family Peptidase_S15 PF02129.13 OAJ28608.1 - 0.0048 16.3 0.6 0.0067 15.8 0.4 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DAO PF01266.19 OAJ28611.1 - 3.1e-17 62.5 0.0 2e-07 30.2 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ28611.1 - 0.00044 20.2 0.3 0.001 19.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAJ28611.1 - 0.00048 19.0 0.0 0.00069 18.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 OAJ28611.1 - 0.0011 18.3 0.1 0.0021 17.5 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 OAJ28611.1 - 0.0022 17.1 0.5 0.0037 16.3 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 OAJ28611.1 - 0.0035 17.7 0.8 0.0068 16.7 0.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 OAJ28611.1 - 0.004 16.5 0.2 0.0075 15.6 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.9 OAJ28611.1 - 0.017 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ28611.1 - 0.051 12.6 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 OAJ28611.1 - 0.13 11.8 0.4 0.31 10.6 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 OAJ28611.1 - 0.15 10.4 0.1 0.22 9.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein MIR PF02815.14 OAJ28612.1 - 1.1e-07 31.5 0.0 3.7e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 MIR domain DHC PF09626.5 OAJ28612.1 - 0.11 13.2 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Dihaem cytochrome c Cu_amine_oxid PF01179.15 OAJ28614.1 - 6e-156 519.3 0.0 7.3e-156 519.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 OAJ28614.1 - 2.5e-14 53.1 0.0 5.8e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 OAJ28614.1 - 0.00046 20.2 0.1 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CRM1_C PF08767.6 OAJ28615.1 - 6.8e-121 403.0 1.0 6.8e-121 403.0 0.7 2.5 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 OAJ28615.1 - 4.1e-40 137.1 2.1 4.1e-40 137.1 1.5 3.9 4 1 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 OAJ28615.1 - 5.1e-13 48.7 0.6 2.2e-12 46.7 0.4 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF1654 PF07867.6 OAJ28615.1 - 0.14 11.5 1.8 13 5.2 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) DnaJ PF00226.26 OAJ28616.1 - 8.5e-07 28.6 0.1 1.3e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Ank_2 PF12796.2 OAJ28617.1 - 1.6e-54 182.1 6.0 3.4e-20 72.1 0.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ28617.1 - 4.6e-36 120.8 6.4 4.6e-09 35.6 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat SPX PF03105.14 OAJ28617.1 - 4.9e-33 115.0 1.3 1.5e-18 67.5 0.0 3.0 3 1 0 3 3 3 2 SPX domain Ank_4 PF13637.1 OAJ28617.1 - 3.7e-32 110.1 3.8 5.4e-11 42.7 0.0 5.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ28617.1 - 1.2e-29 101.6 13.0 6.2e-06 26.2 0.0 7.6 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ28617.1 - 1.5e-22 77.4 1.6 0.0031 17.6 0.0 7.8 8 0 0 8 8 8 5 Ankyrin repeat GDPD PF03009.12 OAJ28617.1 - 1.9e-12 47.2 0.0 3.6e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family zf-C2H2 PF00096.21 OAJ28618.1 - 2.7e-06 27.3 4.7 0.0076 16.5 0.1 2.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 OAJ28618.1 - 4.7e-05 23.3 5.6 0.01 15.9 0.4 2.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 OAJ28618.1 - 8.1e-05 22.6 4.4 0.0034 17.6 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 OAJ28618.1 - 0.00011 22.2 1.9 0.078 13.1 0.2 2.2 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.14 OAJ28618.1 - 0.1 12.2 0.2 0.17 11.6 0.2 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C2H2_6 PF13912.1 OAJ28618.1 - 0.14 12.1 2.1 0.26 11.2 0.1 2.3 1 1 1 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 OAJ28618.1 - 0.14 12.2 0.8 2 8.5 0.5 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 OAJ28618.1 - 0.29 11.4 5.6 0.74 10.2 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger double domain PyrI_C PF02748.10 OAJ28618.1 - 1.1 8.7 3.1 1.3 8.4 0.1 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-H2C2_5 PF13909.1 OAJ28618.1 - 2.4 8.5 5.7 18 5.7 1.2 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Ribosomal_60s PF00428.14 OAJ28619.1 - 3.3e-26 91.5 7.3 3.9e-26 91.2 5.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein OAD_beta PF03977.8 OAJ28619.1 - 0.059 12.0 0.3 0.069 11.8 0.2 1.1 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit Peptidase_C27 PF05407.7 OAJ28619.1 - 0.092 12.4 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Rubella virus endopeptidase Pkinase PF00069.20 OAJ28620.1 - 1.6e-69 233.9 0.0 2e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28620.1 - 2.1e-30 105.6 0.0 2.8e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ28620.1 - 0.0021 17.0 0.0 0.18 10.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.6 OAJ28620.1 - 0.051 12.4 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 OAJ28620.1 - 0.089 12.5 0.0 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family HsbA PF12296.3 OAJ28621.1 - 2.5e-14 53.1 7.0 4e-14 52.5 4.8 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A ALS_ss_C PF10369.4 OAJ28621.1 - 0.067 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Small subunit of acetolactate synthase TPP_enzyme_C PF02775.16 OAJ28621.1 - 0.07 12.7 0.1 0.091 12.3 0.1 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF2721 PF11026.3 OAJ28622.1 - 0.87 9.2 10.7 0.65 9.6 0.3 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) ENTH PF01417.15 OAJ28623.1 - 2.8e-44 149.9 0.1 3.8e-44 149.5 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 OAJ28623.1 - 0.0018 17.0 0.1 0.0024 16.6 0.1 1.1 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 OAJ28623.1 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 VHS domain TPR_12 PF13424.1 OAJ28624.1 - 9.8e-39 131.1 56.3 7.3e-09 35.4 0.4 8.7 2 1 8 11 11 11 10 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ28624.1 - 2.4e-24 84.4 40.2 0.00052 19.8 0.2 12.5 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ28624.1 - 2.1e-08 33.3 6.5 7.5 6.5 0.0 9.4 10 1 0 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ28624.1 - 1.8e-06 27.4 23.8 0.31 10.7 0.6 7.5 3 1 6 9 9 9 7 TPR repeat SHNi-TPR PF10516.4 OAJ28624.1 - 3.1e-06 26.2 6.9 1.7 7.9 0.1 7.0 7 0 0 7 7 7 1 SHNi-TPR TPR_1 PF00515.23 OAJ28624.1 - 8.8e-06 25.1 11.7 0.79 9.4 0.0 9.0 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ28624.1 - 3.6e-05 23.3 26.8 0.73 9.9 0.1 10.6 12 0 0 12 12 11 1 Tetratricopeptide repeat Apc5 PF12862.2 OAJ28624.1 - 0.00043 20.0 9.7 27 4.7 0.0 7.7 4 2 2 6 6 6 0 Anaphase-promoting complex subunit 5 TPR_19 PF14559.1 OAJ28624.1 - 0.0033 17.7 6.6 2 8.8 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat DUF2186 PF09952.4 OAJ28624.1 - 0.0058 16.8 0.7 0.4 10.9 0.0 3.3 3 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2186) DUF3856 PF12968.2 OAJ28624.1 - 0.061 13.1 8.7 4.9 6.9 0.0 5.3 4 1 0 6 6 6 0 Domain of Unknown Function (DUF3856) TPR_7 PF13176.1 OAJ28624.1 - 2.7 8.0 18.2 0.7 9.8 0.0 7.4 10 0 0 10 10 8 0 Tetratricopeptide repeat PPR PF01535.15 OAJ28624.1 - 7.8 6.7 9.0 1.1e+02 3.0 0.0 6.2 6 0 0 6 6 6 0 PPR repeat TPR_4 PF07721.9 OAJ28624.1 - 8.8 7.0 16.0 20 5.9 0.4 6.5 7 0 0 7 7 5 0 Tetratricopeptide repeat PQ-loop PF04193.9 OAJ28625.1 - 6.4e-32 108.8 13.0 2.3e-18 65.5 1.3 2.8 3 0 0 3 3 3 2 PQ loop repeat PLDc_N PF13396.1 OAJ28625.1 - 0.0085 15.7 0.1 0.0085 15.7 0.1 2.4 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal DUF1301 PF06979.7 OAJ28625.1 - 0.16 12.1 0.5 0.45 10.6 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1301) DUF2721 PF11026.3 OAJ28626.1 - 0.24 11.0 9.4 0.22 11.1 0.2 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) Lectin_N PF03954.9 OAJ28626.1 - 0.49 9.7 0.0 0.49 9.7 0.0 2.6 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF3366 PF11846.3 OAJ28626.1 - 4.5 7.1 15.5 0.38 10.5 0.1 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3366) Sec63 PF02889.11 OAJ28629.1 - 2.7e-31 108.9 0.0 5.3e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 OAJ28629.1 - 1.6e-16 59.8 0.3 3.2e-16 58.8 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DUF2305 PF10230.4 OAJ28629.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Peptidase_M16_C PF05193.16 OAJ28630.1 - 0.063 12.9 1.2 0.14 11.8 0.4 2.0 2 0 0 2 2 2 0 Peptidase M16 inactive domain DUF2360 PF10152.4 OAJ28630.1 - 0.98 9.6 6.9 0.98 9.6 2.8 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Utp12 PF04003.7 OAJ28631.1 - 1.3e-09 37.9 2.1 7.2e-08 32.3 0.5 2.3 2 0 0 2 2 2 2 Dip2/Utp12 Family Sds3 PF08598.6 OAJ28632.1 - 3.6e-10 39.7 10.2 3.6e-10 39.7 7.1 2.4 2 0 0 2 2 2 1 Sds3-like Hid1 PF12722.2 OAJ28632.1 - 0.85 7.2 6.3 1.5 6.4 4.4 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Baculo_PP31 PF05311.6 OAJ28632.1 - 2 7.5 19.2 0.03 13.6 1.2 2.4 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Peptidase_C12 PF01088.16 OAJ28633.1 - 2.4e-56 190.2 0.0 2.7e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 PX PF00787.19 OAJ28634.1 - 1.2e-23 83.0 0.1 1.2e-23 83.0 0.1 1.8 2 0 0 2 2 2 1 PX domain PAT1 PF09770.4 OAJ28634.1 - 0.00032 19.1 55.0 0.00039 18.8 38.1 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 OAJ28634.1 - 0.077 11.1 66.6 0.12 10.6 46.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SAGA-Tad1 PF12767.2 OAJ28634.1 - 0.55 9.8 18.2 0.97 9.0 12.6 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2664 PF10867.3 OAJ28635.1 - 0.0092 16.5 4.3 0.014 15.9 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2664) ERM PF00769.14 OAJ28635.1 - 0.012 15.1 8.1 0.016 14.7 5.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Tom37_C PF11801.3 OAJ28635.1 - 0.27 11.0 2.1 0.32 10.8 1.5 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain APG6 PF04111.7 OAJ28635.1 - 0.3 10.0 4.7 0.33 9.9 3.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF572 PF04502.8 OAJ28635.1 - 0.35 10.0 6.5 0.4 9.8 4.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) HlyD PF00529.15 OAJ28635.1 - 0.82 8.9 12.6 0.95 8.7 8.7 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Spc7_N PF15402.1 OAJ28635.1 - 4.3 5.2 10.0 4.3 5.2 6.9 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 FUSC PF04632.7 OAJ28635.1 - 9.2 4.5 9.8 9.5 4.5 6.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FIVAR PF07554.8 OAJ28636.1 - 0.025 14.7 3.3 0.053 13.7 0.9 2.2 1 1 1 2 2 2 0 Uncharacterised Sugar-binding Domain Prominin PF05478.6 OAJ28636.1 - 0.066 10.7 0.2 0.083 10.4 0.1 1.0 1 0 0 1 1 1 0 Prominin FbpA PF05833.6 OAJ28636.1 - 0.075 11.5 0.2 0.088 11.3 0.1 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HCaRG PF07258.9 OAJ28636.1 - 0.13 11.8 0.8 2.2 7.7 0.4 2.0 1 1 1 2 2 2 0 HCaRG protein YwqJ-deaminase PF14431.1 OAJ28636.1 - 0.13 12.1 0.3 0.26 11.1 0.1 1.5 1 1 1 2 2 2 0 YwqJ-like deaminase BssS PF13991.1 OAJ28636.1 - 0.14 11.9 0.2 0.29 10.8 0.1 1.6 1 1 0 1 1 1 0 BssS protein family ATP-synt_DE PF00401.15 OAJ28636.1 - 2.2 8.2 8.6 0.45 10.4 0.6 2.4 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Abhydrolase_5 PF12695.2 OAJ28637.1 - 2.1e-09 37.3 0.8 5.5e-09 35.9 0.5 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ28637.1 - 1.3e-06 27.8 0.0 3.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 OAJ28637.1 - 0.00075 19.1 0.1 0.0072 15.9 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 OAJ28637.1 - 0.0044 15.9 0.1 0.2 10.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Esterase PF00756.15 OAJ28639.1 - 1.6e-05 24.4 0.0 3.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 OAJ28639.1 - 0.00024 20.8 0.0 0.00091 19.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ28639.1 - 0.0022 17.9 0.6 0.0052 16.6 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Pterin_4a PF01329.14 OAJ28640.1 - 1e-25 89.3 0.2 1.3e-25 89.0 0.1 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase KSHV_K8 PF07188.6 OAJ28640.1 - 0.089 12.0 0.1 0.08 12.1 0.1 1.1 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein UPF0086 PF01868.11 OAJ28641.1 - 5.2e-12 45.2 0.0 1.6e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function UPF0086 Sdh5 PF03937.11 OAJ28643.1 - 1.4e-22 79.1 0.3 8.9e-22 76.5 0.1 2.1 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase GIY-YIG PF01541.19 OAJ28645.1 - 1.2e-05 25.5 0.0 8.9e-05 22.7 0.0 2.5 3 0 0 3 3 3 1 GIY-YIG catalytic domain Tmemb_55A PF09788.4 OAJ28645.1 - 0.052 12.6 0.5 0.084 11.9 0.0 1.5 2 0 0 2 2 2 0 Transmembrane protein 55A Macoilin PF09726.4 OAJ28645.1 - 0.4 8.8 11.5 0.78 7.9 7.9 1.4 1 0 0 1 1 1 0 Transmembrane protein Cyclin PF08613.6 OAJ28646.1 - 1e-10 42.2 0.0 2.5e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Cyclin DUF1275 PF06912.6 OAJ28647.1 - 8e-25 87.2 14.8 1e-24 86.8 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) YibE_F PF07907.6 OAJ28647.1 - 0.1 11.7 9.2 0.21 10.7 5.5 1.9 1 1 0 1 1 1 0 YibE/F-like protein Mito_carr PF00153.22 OAJ28648.1 - 2.5e-47 158.5 0.0 2.3e-15 56.0 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein TrkH PF02386.11 OAJ28649.1 - 1.6e-87 293.4 14.7 4.4e-86 288.6 3.6 2.1 2 0 0 2 2 2 2 Cation transport protein CytochromB561_N PF09786.4 OAJ28649.1 - 0.01 14.3 0.1 0.016 13.6 0.1 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal ERO1 PF04137.10 OAJ28650.1 - 2.7e-117 391.7 0.0 1.8e-115 385.7 0.0 2.1 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) LCAT PF02450.10 OAJ28651.1 - 6e-82 275.6 0.1 1.1e-81 274.7 0.1 1.4 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF2523 PF10734.4 OAJ28651.1 - 0.2 11.9 1.7 0.44 10.8 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2523) TRAPP PF04051.11 OAJ28652.1 - 7.1e-36 123.0 0.0 1.1e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component ATP-grasp_2 PF08442.5 OAJ28653.1 - 3.9e-68 228.8 0.1 6.6e-68 228.0 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 OAJ28653.1 - 2e-23 82.7 0.8 3.6e-23 81.8 0.5 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 OAJ28653.1 - 3.1e-12 46.2 0.1 5.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 OAJ28653.1 - 0.001 18.7 0.1 0.0025 17.3 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.12 OAJ28653.1 - 0.025 13.8 0.1 0.065 12.5 0.0 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 OAJ28653.1 - 0.053 13.2 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.17 OAJ28653.1 - 0.062 12.6 0.1 0.18 11.1 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain HipA_N PF07805.7 OAJ28653.1 - 0.077 13.2 0.1 1.6 9.0 0.0 2.8 2 0 0 2 2 2 0 HipA-like N-terminal domain ApbA PF02558.11 OAJ28654.1 - 4.5e-27 94.3 0.0 7e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 OAJ28654.1 - 2.5e-26 92.1 0.0 5.9e-26 90.9 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal DAO PF01266.19 OAJ28654.1 - 0.0022 16.9 0.2 0.006 15.5 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAJ28654.1 - 0.036 13.1 0.0 0.064 12.2 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain ThiF PF00899.16 OAJ28654.1 - 0.064 13.0 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.22 OAJ28654.1 - 0.15 12.4 0.1 0.36 11.2 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TAF PF02969.12 OAJ28655.1 - 1.3e-21 76.2 0.0 3.7e-21 74.8 0.0 1.8 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 OAJ28655.1 - 7.4e-13 48.4 0.3 1.2e-11 44.5 0.2 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1546) Histone PF00125.19 OAJ28655.1 - 7.3e-06 26.0 0.5 1.9e-05 24.6 0.3 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF4611 PF15387.1 OAJ28655.1 - 0.014 15.5 0.3 0.87 9.7 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) TFIID-31kDa PF02291.10 OAJ28655.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit MSP1_C PF07462.6 OAJ28655.1 - 0.17 10.2 1.1 0.3 9.4 0.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RRM_1 PF00076.17 OAJ28656.1 - 3.3e-15 55.4 0.0 4.9e-07 29.2 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ28656.1 - 1.7e-12 47.1 0.0 1.2e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ28656.1 - 7e-05 22.6 0.0 0.0055 16.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) E1-E2_ATPase PF00122.15 OAJ28659.1 - 3.9e-64 215.8 5.0 1.2e-63 214.2 2.7 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAJ28659.1 - 5.4e-49 166.1 4.2 1.1e-47 161.8 1.1 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ28659.1 - 1.2e-32 114.0 0.1 7.5e-32 111.4 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAJ28659.1 - 1.2e-20 72.7 0.0 3.5e-20 71.2 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 OAJ28659.1 - 4.8e-18 64.8 0.0 8.8e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 OAJ28659.1 - 8.7e-15 55.3 0.6 2.2e-14 54.0 0.4 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ28659.1 - 2.8e-06 27.1 0.9 5.9e-05 22.7 0.5 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 OAJ28659.1 - 0.047 13.9 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase US22 PF02393.11 OAJ28659.1 - 0.1 12.5 0.0 0.49 10.4 0.0 2.2 2 0 0 2 2 2 0 US22 like SASP_gamma PF04259.9 OAJ28660.1 - 0.26 11.4 2.4 0.54 10.4 1.1 1.7 1 1 0 1 1 1 0 Small, acid-soluble spore protein, gamma-type PHD PF00628.24 OAJ28661.1 - 2.1e-08 33.7 8.4 2.1e-08 33.7 5.8 1.8 2 0 0 2 2 2 1 PHD-finger Xpo1 PF08389.7 OAJ28662.1 - 1.4e-26 93.2 0.2 4.7e-24 84.9 0.0 3.6 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 OAJ28662.1 - 1.4e-06 28.1 0.3 5.2e-06 26.2 0.1 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain ParcG PF10274.4 OAJ28662.1 - 0.0014 18.5 0.1 0.34 10.7 0.0 3.1 2 1 1 3 3 3 1 Parkin co-regulated protein DUF2489 PF10675.4 OAJ28662.1 - 0.048 13.3 0.1 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) HEAT PF02985.17 OAJ28662.1 - 0.6 10.3 4.2 1.4 9.1 0.1 3.8 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 OAJ28662.1 - 2.3 8.8 15.9 2 9.0 0.1 6.3 4 2 2 6 6 6 0 HEAT-like repeat Indigoidine_A PF04227.7 OAJ28663.1 - 4.3e-107 357.6 1.1 4.3e-107 357.6 0.8 1.6 2 0 0 2 2 2 1 Indigoidine synthase A like protein PfkB PF00294.19 OAJ28663.1 - 2.2e-17 63.1 1.3 1.2e-09 37.7 0.1 2.4 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Sec10 PF07393.6 OAJ28664.1 - 4.3e-238 792.1 0.0 5.5e-238 791.7 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Kri1 PF05178.7 OAJ28664.1 - 0.055 13.7 0.3 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 KRI1-like family MscS_porin PF12795.2 OAJ28664.1 - 0.31 10.3 0.1 0.57 9.4 0.1 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DNA_ligase_A_M PF01068.16 OAJ28665.1 - 6.8e-37 126.8 0.0 1.9e-25 89.4 0.0 3.9 3 1 0 3 3 3 3 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 OAJ28665.1 - 5.9e-35 120.6 0.1 1.6e-34 119.2 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 OAJ28665.1 - 1e-17 64.3 0.1 6e-17 61.8 0.0 2.5 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Myb_DNA-binding PF00249.26 OAJ28666.1 - 7e-19 67.6 4.7 4.5e-14 52.2 1.4 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ28666.1 - 2.4e-13 49.9 4.9 2.7e-12 46.6 1.8 4.1 2 1 2 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ28666.1 - 2.6e-05 24.2 8.7 0.0057 16.7 0.0 3.4 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 OAJ28666.1 - 0.045 13.9 0.8 0.045 13.9 0.6 2.6 3 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like CNH PF00780.17 OAJ28667.1 - 0.48 9.7 0.0 31 3.8 0.0 2.2 2 0 0 2 2 2 0 CNH domain GST_C_3 PF14497.1 OAJ28669.1 - 1.6e-08 34.9 0.0 2.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAJ28669.1 - 2.8e-07 30.4 0.0 4.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ28669.1 - 0.0013 18.5 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RhoGEF PF00621.15 OAJ28670.1 - 2.4e-12 47.1 0.0 2.7e-08 33.9 0.0 2.5 2 1 0 2 2 2 2 RhoGEF domain PH PF00169.24 OAJ28670.1 - 0.00022 21.3 0.0 0.00041 20.5 0.0 1.4 1 0 0 1 1 1 1 PH domain La PF05383.12 OAJ28671.1 - 2.5e-12 46.3 0.1 1e-05 25.1 0.3 2.5 2 0 0 2 2 2 2 La domain RRM_1 PF00076.17 OAJ28671.1 - 2e-06 27.3 0.1 4.4e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ28671.1 - 8.9e-05 22.3 0.0 0.00021 21.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ28671.1 - 0.021 14.6 0.0 0.065 13.1 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyt-b5 PF00173.23 OAJ28672.1 - 1.4e-23 82.5 0.2 1.5e-23 82.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 OAJ28672.1 - 0.04 13.8 0.0 0.08 12.8 0.0 1.5 1 1 0 1 1 1 0 V-ATPase subunit H HlyIII PF03006.15 OAJ28673.1 - 4.8e-50 170.0 21.1 6e-50 169.7 14.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related ABC2_membrane_5 PF13346.1 OAJ28673.1 - 0.47 9.7 7.0 0.37 10.0 3.3 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Arrestin_C PF02752.17 OAJ28674.1 - 1.5e-05 25.1 0.0 4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 OAJ28674.1 - 0.0011 18.8 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain TFIIA_gamma_N PF02268.11 OAJ28676.1 - 9e-26 89.2 0.1 1.2e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 OAJ28676.1 - 7.6e-23 80.0 0.3 1e-22 79.6 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DUF2414 PF10309.4 OAJ28677.1 - 8.5e-05 22.1 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 OAJ28677.1 - 0.00012 21.9 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain RRM_3 PF08777.6 OAJ28677.1 - 0.033 14.0 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif MAPEG PF01124.13 OAJ28679.1 - 1.9e-24 85.7 1.7 2.3e-24 85.4 1.2 1.1 1 0 0 1 1 1 1 MAPEG family TPR_12 PF13424.1 OAJ28681.1 - 9.5e-15 54.3 27.6 5.1e-06 26.3 4.3 5.8 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ28681.1 - 1.2e-07 31.4 21.4 0.3 11.0 1.5 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ28681.1 - 0.00033 20.1 11.4 6.6 6.5 0.5 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat DUF3856 PF12968.2 OAJ28681.1 - 0.0013 18.6 6.9 0.66 9.7 0.1 3.8 1 1 2 3 3 3 2 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.4 OAJ28681.1 - 0.0016 17.6 7.4 0.63 9.3 0.0 4.2 5 0 0 5 5 5 2 SHNi-TPR Apc5 PF12862.2 OAJ28681.1 - 0.0018 18.0 13.8 6.4 6.6 0.1 6.5 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 5 TPR_2 PF07719.12 OAJ28681.1 - 0.0051 16.6 24.8 10 6.3 0.5 8.4 8 2 1 9 9 9 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ28681.1 - 0.027 15.0 14.5 13 6.7 0.7 6.6 7 1 0 7 7 7 0 Tetratricopeptide repeat DUF4288 PF14119.1 OAJ28681.1 - 0.93 9.6 3.7 4.8 7.3 0.1 3.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4288) TPR_16 PF13432.1 OAJ28681.1 - 4.4 8.1 20.0 6.4 7.5 2.0 6.1 4 2 3 7 7 7 0 Tetratricopeptide repeat DinB_2 PF12867.2 OAJ28682.1 - 0.039 14.2 2.0 2.6 8.3 0.2 2.6 2 0 0 2 2 2 0 DinB superfamily FAM60A PF15396.1 OAJ28682.1 - 0.76 9.4 16.0 0.03 14.0 3.8 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DNA_pol_viral_N PF00242.12 OAJ28682.1 - 1.6 7.6 17.6 0.095 11.7 5.7 2.1 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Cwf_Cwc_15 PF04889.7 OAJ28682.1 - 3.7 7.2 24.1 0.53 9.9 9.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein OB_NTP_bind PF07717.11 OAJ28685.1 - 3.1e-25 88.2 0.0 6.5e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 OAJ28685.1 - 2.8e-21 75.4 0.0 5.9e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ28685.1 - 7.1e-15 54.6 0.0 1.4e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ28685.1 - 3.2e-05 23.4 0.0 7.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ28685.1 - 7.1e-05 22.9 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 OAJ28685.1 - 0.01 15.7 0.0 0.09 12.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 OAJ28685.1 - 0.1 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase T2SE PF00437.15 OAJ28685.1 - 0.11 11.4 0.0 0.27 10.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 OAJ28685.1 - 0.15 11.2 0.0 0.92 8.7 0.0 2.2 2 1 1 3 3 3 0 PhoH-like protein LAG1-DNAbind PF09271.6 OAJ28686.1 - 5.6e-23 81.9 0.0 1.2e-18 67.9 0.0 2.5 2 0 0 2 2 2 2 LAG1, DNA binding BTD PF09270.5 OAJ28686.1 - 3e-17 62.8 0.0 6.6e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF2205 PF10224.4 OAJ28687.1 - 2.6e-15 55.7 0.0 3.5e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 OAJ28687.1 - 0.00095 19.4 0.0 0.0011 19.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Cast PF10174.4 OAJ28687.1 - 0.08 10.9 0.0 0.09 10.8 0.0 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Metallophos PF00149.23 OAJ28688.1 - 1.3e-40 138.9 0.9 1.9e-40 138.4 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase V-ATPase_G PF03179.10 OAJ28689.1 - 1.2e-20 73.7 11.8 1.3e-20 73.6 8.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 OAJ28689.1 - 0.0012 18.6 11.7 0.0012 18.6 8.1 1.0 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) DUF3552 PF12072.3 OAJ28689.1 - 0.06 12.5 9.9 0.059 12.5 6.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) vATP-synt_E PF01991.13 OAJ28689.1 - 0.35 10.0 9.4 0.38 9.9 6.5 1.0 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Seryl_tRNA_N PF02403.17 OAJ28689.1 - 0.38 10.8 6.1 0.59 10.1 4.3 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3072 PF11272.3 OAJ28689.1 - 4.5 7.0 6.0 88 2.8 4.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3072) DUF2461 PF09365.5 OAJ28690.1 - 1.2e-55 188.1 0.0 1.7e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Pkinase PF00069.20 OAJ28691.1 - 1.1e-59 201.7 0.0 2.3e-34 118.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28691.1 - 8.7e-23 80.7 0.0 2.1e-20 72.8 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase WD40 PF00400.27 OAJ28692.1 - 7e-09 35.2 4.3 0.0046 16.7 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Macoilin PF09726.4 OAJ28692.1 - 0.83 7.8 4.4 1.2 7.2 0.4 2.4 2 0 0 2 2 2 0 Transmembrane protein FAD_binding_3 PF01494.14 OAJ28693.1 - 1.2e-67 228.4 0.0 1.6e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAJ28693.1 - 2.2e-05 24.4 0.1 7.2e-05 22.7 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ28693.1 - 6.2e-05 23.3 0.0 0.0003 21.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ28693.1 - 9.7e-05 21.4 0.6 0.008 15.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAJ28693.1 - 0.00026 20.1 0.0 0.0004 19.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 OAJ28693.1 - 0.00076 19.4 0.2 0.002 18.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAJ28693.1 - 0.00095 18.1 0.2 0.0016 17.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 OAJ28693.1 - 0.0025 16.7 0.3 0.0046 15.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 OAJ28693.1 - 0.0041 15.6 0.4 0.0066 14.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 OAJ28693.1 - 0.027 13.3 0.4 0.041 12.7 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 OAJ28693.1 - 0.036 14.1 0.2 0.086 12.8 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 OAJ28693.1 - 0.072 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 OAJ28693.1 - 0.073 12.8 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 ThiF family adh_short PF00106.20 OAJ28694.1 - 3.6e-21 75.7 3.7 7.2e-21 74.8 2.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ28694.1 - 1e-13 51.6 1.0 1.8e-13 50.8 0.7 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ28694.1 - 3e-09 36.7 0.7 4.5e-09 36.2 0.5 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAJ28694.1 - 6.2e-07 29.0 0.1 9.2e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ28694.1 - 2e-06 27.9 1.4 5.2e-06 26.5 1.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 OAJ28694.1 - 0.022 13.9 0.5 0.039 13.1 0.3 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 OAJ28694.1 - 0.046 12.6 0.1 0.12 11.2 0.1 1.9 2 1 0 2 2 2 0 RmlD substrate binding domain TrkA_N PF02254.13 OAJ28694.1 - 0.076 13.0 0.5 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain 3Beta_HSD PF01073.14 OAJ28694.1 - 0.09 11.4 0.2 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_2 PF00891.13 OAJ28695.1 - 6.9e-32 110.5 0.0 1e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 OAJ28695.1 - 0.0006 20.3 0.0 0.0015 19.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain HTH_IclR PF09339.5 OAJ28695.1 - 0.0075 15.8 0.3 2.2 7.9 0.0 2.7 2 0 0 2 2 2 2 IclR helix-turn-helix domain MTS PF05175.9 OAJ28695.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF3115 PF11312.3 OAJ28695.1 - 0.22 10.3 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) Aldo_ket_red PF00248.16 OAJ28696.1 - 7.3e-45 152.9 0.0 8.4e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GSDH PF07995.6 OAJ28697.1 - 2.7e-06 26.7 0.5 1.2e-05 24.6 0.2 2.3 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase Fungal_trans PF04082.13 OAJ28698.1 - 3.6e-07 29.3 0.0 6.5e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ28698.1 - 2e-06 27.5 10.4 3.2e-06 26.9 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 OAJ28699.1 - 0.00048 19.1 19.3 0.00049 19.0 13.4 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Draxin PF15550.1 OAJ28699.1 - 0.02 14.5 5.2 0.022 14.4 3.6 1.0 1 0 0 1 1 1 0 Draxin Apc15p PF05841.6 OAJ28699.1 - 0.062 14.0 11.6 0.08 13.6 8.1 1.2 1 0 0 1 1 1 0 Apc15p protein VAD1-2 PF15310.1 OAJ28699.1 - 0.09 12.4 14.4 0.1 12.2 10.0 1.1 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling CTNNB1_binding PF08347.6 OAJ28699.1 - 0.13 12.5 10.4 0.16 12.2 7.2 1.1 1 0 0 1 1 1 0 N-terminal CTNNB1 binding FCP1_C PF09309.5 OAJ28699.1 - 0.19 11.0 8.3 0.26 10.5 5.7 1.3 1 0 0 1 1 1 0 FCP1, C-terminal Suf PF05843.9 OAJ28699.1 - 0.21 11.2 10.1 0.22 11.2 7.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Gti1_Pac2 PF09729.4 OAJ28699.1 - 0.21 11.4 3.6 0.24 11.2 2.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Plasmodium_Vir PF05795.6 OAJ28699.1 - 0.27 10.4 1.8 0.31 10.2 1.2 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4557 PF15101.1 OAJ28699.1 - 0.32 10.8 14.5 0.35 10.6 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) MCPVI PF02993.9 OAJ28699.1 - 0.38 10.8 11.4 0.47 10.5 7.9 1.0 1 0 0 1 1 1 0 Minor capsid protein VI FimP PF09766.4 OAJ28699.1 - 0.43 9.5 17.1 0.54 9.2 11.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein Ctr PF04145.10 OAJ28699.1 - 0.48 10.4 3.1 0.57 10.2 2.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF4175 PF13779.1 OAJ28699.1 - 0.53 7.9 26.4 0.63 7.6 18.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Tim54 PF11711.3 OAJ28699.1 - 0.72 8.3 4.9 0.84 8.1 3.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S64 PF08192.6 OAJ28699.1 - 0.75 8.0 5.9 0.89 7.8 4.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 Spt20 PF12090.3 OAJ28699.1 - 0.77 9.0 13.0 1 8.6 9.0 1.2 1 0 0 1 1 1 0 Spt20 family PSI_PsaJ PF01701.13 OAJ28699.1 - 1.1 9.1 3.2 2 8.2 2.2 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ Lin-8 PF03353.10 OAJ28699.1 - 1.3 8.2 12.0 1.4 8.1 8.3 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2457 PF10446.4 OAJ28699.1 - 1.4 7.5 7.9 1.5 7.5 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Spc7_N PF15402.1 OAJ28699.1 - 1.5 6.7 11.4 1.7 6.5 7.9 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Macoilin PF09726.4 OAJ28699.1 - 1.6 6.9 8.2 1.9 6.7 5.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Otopetrin PF03189.8 OAJ28699.1 - 1.7 7.5 4.7 2.2 7.2 3.3 1.0 1 0 0 1 1 1 0 Otopetrin Pex16 PF08610.5 OAJ28699.1 - 2.1 7.2 8.2 2.1 7.2 5.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) CDK5_activator PF03261.10 OAJ28699.1 - 2.2 7.5 11.9 2.6 7.2 8.2 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein MRF_C2 PF13888.1 OAJ28699.1 - 2.2 8.0 8.9 3.5 7.4 5.0 1.9 2 0 0 2 2 2 0 Myelin gene regulatory factor C-terminal domain 2 CagX PF03524.10 OAJ28699.1 - 2.3 7.4 9.1 3.2 6.9 6.3 1.2 1 0 0 1 1 1 0 Conjugal transfer protein UPF0560 PF10577.4 OAJ28699.1 - 3.3 5.8 16.8 4 5.5 11.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Hid1 PF12722.2 OAJ28699.1 - 4.5 4.8 10.0 4.8 4.7 6.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EIIBC-GUT_N PF03612.9 OAJ28699.1 - 4.8 6.7 6.2 6.8 6.2 4.3 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus AIF_C PF14721.1 OAJ28699.1 - 7.2 6.8 7.6 12 6.1 5.3 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Radical_SAM_N PF08497.5 OAJ28699.1 - 7.5 5.3 7.1 9.8 4.9 4.9 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal TFIIA PF03153.8 OAJ28699.1 - 8.7 6.1 21.0 10 5.8 14.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SHS2_Rpb7-N PF03876.12 OAJ28701.1 - 3.4e-14 52.7 0.0 5.5e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 OAJ28701.1 - 4.5e-11 42.6 0.1 6.5e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 OAJ28701.1 - 0.033 14.3 0.0 0.049 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 DUF3682 PF12446.3 OAJ28702.1 - 0.0016 18.6 8.5 0.0016 18.6 5.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3682) RVT_1 PF00078.22 OAJ28703.1 - 6.9e-24 84.3 0.0 1.1e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAJ28703.1 - 2.8e-17 63.2 0.0 5.8e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 OAJ28703.1 - 4.7e-16 58.4 0.1 1.5e-15 56.8 0.1 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ28703.1 - 2.1e-07 31.1 1.3 8.7e-07 29.1 0.4 2.3 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 OAJ28703.1 - 0.036 14.3 1.2 0.13 12.5 0.8 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase G-patch PF01585.18 OAJ28705.1 - 0.0021 17.7 1.0 0.0075 16.0 0.7 2.0 1 0 0 1 1 1 1 G-patch domain DSPc PF00782.15 OAJ28706.1 - 6.3e-28 97.0 0.0 7.2e-22 77.3 0.0 2.7 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAJ28706.1 - 0.00026 20.4 0.0 0.00081 18.7 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 OAJ28706.1 - 0.15 12.1 0.1 0.99 9.4 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate Exo_endo_phos_2 PF14529.1 OAJ28708.1 - 3.3e-12 46.0 0.0 1.1e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ28708.1 - 1.1e-06 28.7 0.4 2.2e-06 27.8 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 OAJ28708.1 - 1.5e-05 24.4 0.0 0.00036 19.9 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) GARS_N PF02844.10 OAJ28709.1 - 1.9e-36 124.5 0.2 2.3e-36 124.2 0.2 1.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain p450 PF00067.17 OAJ28710.1 - 2.6e-63 214.1 0.0 3.5e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PLA2_B PF01735.13 OAJ28712.1 - 4e-12 45.0 0.0 2.7e-06 25.8 0.9 2.6 2 1 0 2 2 2 2 Lysophospholipase catalytic domain SUZ PF12752.2 OAJ28713.1 - 1.1e-10 41.9 1.8 1.1e-10 41.9 1.2 2.8 3 1 0 3 3 3 1 SUZ domain Metallophos_2 PF12850.2 OAJ28714.1 - 1.1e-19 70.8 0.0 1.7e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 OAJ28714.1 - 0.00056 19.3 1.5 0.015 14.6 0.0 2.2 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase TFIIF_alpha PF05793.7 OAJ28714.1 - 5 5.3 18.0 6.8 4.9 12.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HhH-GPD PF00730.20 OAJ28716.1 - 2.2e-12 47.1 0.0 4.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein TraG-D_C PF12696.2 OAJ28716.1 - 1.5 8.6 4.0 25 4.7 2.9 2.2 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG FHA PF00498.21 OAJ28717.1 - 0.0093 16.0 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain FHA PF00498.21 OAJ28718.1 - 0.00038 20.5 0.0 0.0013 18.8 0.0 1.8 2 0 0 2 2 2 1 FHA domain TRIC PF05197.8 OAJ28720.1 - 0.13 11.6 0.0 0.55 9.6 0.0 1.9 2 0 0 2 2 2 0 TRIC channel U79_P34 PF03064.11 OAJ28721.1 - 0.22 11.0 3.3 0.39 10.1 2.3 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 tRNA-synt_His PF13393.1 OAJ28722.1 - 0.0067 15.5 0.0 0.0083 15.2 0.0 1.0 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Uso1_p115_C PF04871.8 OAJ28723.1 - 0.019 14.8 0.4 0.066 13.1 0.2 2.1 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Exo_endo_phos_2 PF14529.1 OAJ28724.1 - 9.2e-12 44.6 0.0 2e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 OAJ28724.1 - 2.8e-06 27.1 3.1 3.4e-05 23.6 2.1 2.4 1 1 0 1 1 1 1 GRF zinc finger DUF3808 PF10300.4 OAJ28725.1 - 1.8e-77 260.8 0.0 3e-77 260.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) CRAL_TRIO PF00650.15 OAJ28725.1 - 1.6e-31 108.9 0.0 3.1e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ28725.1 - 4.1e-12 46.0 0.6 1.3e-11 44.4 0.4 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 OAJ28725.1 - 5.2e-12 45.9 0.1 2.4e-11 43.7 0.0 2.1 3 0 0 3 3 3 1 Divergent CRAL/TRIO domain TPR_11 PF13414.1 OAJ28725.1 - 0.00049 19.6 6.6 0.068 12.8 2.3 3.6 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 OAJ28725.1 - 0.15 12.0 10.9 21 5.3 1.2 5.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ28725.1 - 0.74 9.5 7.4 0.93 9.2 0.9 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ28725.1 - 2 8.4 12.7 0.34 10.8 2.2 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF383 PF04063.9 OAJ28726.1 - 4.2e-58 196.0 0.0 2.7e-57 193.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 OAJ28726.1 - 1.6e-18 66.0 1.5 3.2e-18 65.0 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) DUF883 PF05957.8 OAJ28726.1 - 0.042 14.2 0.5 0.042 14.2 0.4 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) AAA_18 PF13238.1 OAJ28727.1 - 8.2e-22 77.8 0.0 2.7e-21 76.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ28727.1 - 7.9e-09 36.3 0.0 1.7e-08 35.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ28727.1 - 0.0042 16.9 0.1 0.6 9.9 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_28 PF13521.1 OAJ28727.1 - 0.0061 16.5 0.0 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 OAJ28727.1 - 0.016 14.4 0.0 0.051 12.7 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 OAJ28727.1 - 0.022 14.7 0.4 0.068 13.1 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 OAJ28727.1 - 0.03 14.0 0.1 0.068 12.9 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 OAJ28727.1 - 0.033 13.3 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 OAJ28727.1 - 0.045 13.8 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 OAJ28727.1 - 0.048 13.8 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 OAJ28727.1 - 0.053 12.9 0.1 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ADK PF00406.17 OAJ28727.1 - 0.056 13.3 0.1 6.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase AAA_29 PF13555.1 OAJ28727.1 - 0.098 12.2 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sdh_cyt PF01127.17 OAJ28728.1 - 3.4e-23 81.7 4.9 4.7e-23 81.3 3.4 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Pam16 PF03656.8 OAJ28728.1 - 0.082 12.7 0.3 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Pam16 FSIP1 PF15554.1 OAJ28728.1 - 0.27 9.9 2.5 0.36 9.5 1.7 1.0 1 0 0 1 1 1 0 FSIP1 family His_Phos_1 PF00300.17 OAJ28729.1 - 8.7e-16 58.4 0.0 1.4e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.20 OAJ28730.1 - 1.1e-52 178.8 0.0 6.8e-34 117.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28730.1 - 8.1e-23 80.8 0.1 1.4e-15 57.1 0.0 2.7 2 1 1 3 3 3 2 Protein tyrosine kinase APH PF01636.18 OAJ28730.1 - 0.002 17.8 1.4 0.054 13.2 0.1 2.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ28730.1 - 0.038 12.9 0.0 0.18 10.7 0.0 2.0 2 0 0 2 2 2 0 Kinase-like AA_permease_2 PF13520.1 OAJ28731.1 - 6.5e-62 209.4 38.9 8.3e-62 209.0 27.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAJ28731.1 - 7.5e-30 103.6 35.2 1.1e-29 103.0 24.4 1.2 1 0 0 1 1 1 1 Amino acid permease Semialdhyde_dhC PF02774.13 OAJ28733.1 - 1.7e-42 145.3 0.1 2.9e-42 144.6 0.0 1.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 OAJ28733.1 - 2.5e-28 98.8 0.0 5.1e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 OAJ28733.1 - 0.00032 20.6 0.0 0.00081 19.3 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.15 OAJ28733.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.11 OAJ28733.1 - 0.065 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase SNARE PF05739.14 OAJ28735.1 - 5.3e-17 61.2 1.0 5.3e-17 61.2 0.7 2.2 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.1 OAJ28735.1 - 3.4e-11 43.0 3.6 5.6e-11 42.3 1.3 2.1 2 1 0 2 2 2 1 Syntaxin-like protein MCPsignal PF00015.16 OAJ28735.1 - 0.013 15.0 0.9 0.013 15.0 0.6 2.0 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin PF00804.20 OAJ28735.1 - 0.51 10.5 5.4 0.29 11.3 1.0 2.5 2 1 0 2 2 2 0 Syntaxin DnaJ PF00226.26 OAJ28736.1 - 2.8e-18 65.4 0.1 9.6e-18 63.6 0.0 2.0 1 0 0 1 1 1 1 DnaJ domain AAA_23 PF13476.1 OAJ28736.1 - 0.1 12.9 8.1 0.18 12.1 5.6 1.3 1 0 0 1 1 1 0 AAA domain ELFV_dehydrog PF00208.16 OAJ28738.1 - 4.2e-48 164.0 0.2 4.8e-48 163.8 0.1 1.0 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF390 PF04094.9 OAJ28738.1 - 0.025 12.6 0.2 0.031 12.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) WGG PF10273.4 OAJ28739.1 - 1.1e-21 76.7 0.0 2e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 OAJ28739.1 - 0.021 14.8 1.3 0.021 14.8 0.9 1.6 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) Utp14 PF04615.8 OAJ28739.1 - 0.12 10.5 9.1 0.18 9.9 6.3 1.2 1 0 0 1 1 1 0 Utp14 protein CDC45 PF02724.9 OAJ28739.1 - 2.5 6.0 11.8 3.4 5.5 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 OAJ28739.1 - 4 6.0 18.7 6.8 5.3 12.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pox_RNA_Pol_19 PF05320.7 OAJ28739.1 - 10 5.8 8.3 21 4.8 5.8 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit SKN1 PF03935.10 OAJ28740.1 - 2.1e-81 273.6 0.2 2.6e-81 273.3 0.1 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 OAJ28740.1 - 0.0092 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 OAJ28741.1 - 5.7e-20 70.9 0.0 6e-20 70.8 0.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Aconitase PF00330.15 OAJ28742.1 - 2.7e-174 580.0 0.0 5.8e-174 578.9 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAJ28742.1 - 3.7e-44 150.0 0.0 6.4e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain SKN1 PF03935.10 OAJ28743.1 - 1.2e-144 482.2 9.5 1.1e-101 340.5 5.4 2.2 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 OAJ28743.1 - 8.3e-05 21.9 0.2 0.03 13.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 SKN1 PF03935.10 OAJ28744.1 - 3e-06 25.6 0.0 3.9e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DDE_3 PF13358.1 OAJ28747.1 - 1e-19 70.7 0.0 2.3e-19 69.6 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 OAJ28747.1 - 2.7e-17 62.5 7.2 8.5e-17 60.9 5.0 1.9 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 OAJ28747.1 - 5.5e-05 23.8 1.4 5.5e-05 23.8 0.9 3.2 2 2 1 3 3 3 1 Homeodomain-like domain rve PF00665.21 OAJ28747.1 - 0.0015 18.6 0.0 0.0057 16.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_21 PF13276.1 OAJ28747.1 - 0.0028 17.6 1.5 0.011 15.7 1.0 2.0 1 0 0 1 1 1 1 HTH-like domain DDE_Tnp_ISAZ013 PF07592.6 OAJ28747.1 - 0.0084 14.8 0.2 0.54 8.9 0.1 2.2 2 0 0 2 2 2 1 Rhodopirellula transposase DDE domain HTH_28 PF13518.1 OAJ28747.1 - 0.041 13.8 3.9 0.15 12.0 0.1 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain DUF668 PF05003.7 OAJ28747.1 - 0.081 13.1 0.3 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF668) GcrA PF07750.6 OAJ28747.1 - 0.23 11.6 3.2 0.41 10.8 2.2 1.4 1 0 0 1 1 1 0 GcrA cell cycle regulator HTH_38 PF13936.1 OAJ28747.1 - 1.8 8.1 5.8 6.8 6.3 0.0 3.6 3 1 1 4 4 4 0 Helix-turn-helix domain HLH PF00010.21 OAJ28748.1 - 3.4e-07 29.8 0.0 1e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Suf PF05843.9 OAJ28748.1 - 0.24 11.0 20.9 1.3 8.6 5.8 2.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PBP1_TM PF14812.1 OAJ28748.1 - 2.1 8.6 6.3 1.3 9.4 0.2 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PRANC PF09372.5 OAJ28749.1 - 0.32 10.9 0.0 0.57 10.1 0.0 1.3 1 0 0 1 1 1 0 PRANC domain Citrate_synt PF00285.16 OAJ28750.1 - 1.6e-95 319.9 0.0 1.9e-95 319.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 OAJ28750.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Voltage_CLC PF00654.15 OAJ28752.1 - 1.8e-91 306.7 28.9 1.8e-91 306.7 20.1 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 OAJ28752.1 - 0.0018 18.0 0.0 0.0041 16.8 0.0 1.6 1 0 0 1 1 1 1 CBS domain CBS PF00571.23 OAJ28754.1 - 0.0079 15.9 0.1 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 CBS domain Cutinase PF01083.17 OAJ28757.1 - 2.2e-28 99.2 0.3 2.6e-28 98.9 0.2 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 OAJ28757.1 - 0.037 13.7 0.1 0.045 13.4 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 OAJ28757.1 - 0.042 13.2 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Pro_dh PF01619.13 OAJ28759.1 - 2.3e-33 115.5 0.0 4.1e-17 62.1 0.0 3.3 2 1 0 2 2 2 2 Proline dehydrogenase DPBB_1 PF03330.13 OAJ28760.1 - 1.4e-08 34.5 0.1 2.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ28760.1 - 0.00024 20.7 0.7 0.00041 20.0 0.5 1.6 1 1 0 1 1 1 1 Barwin family PPR_2 PF13041.1 OAJ28761.1 - 9.2e-17 60.7 0.0 0.00057 19.8 0.0 4.6 4 0 0 4 4 4 4 PPR repeat family PPR_3 PF13812.1 OAJ28761.1 - 1.6e-09 37.2 2.7 0.22 11.8 0.0 6.6 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR PF01535.15 OAJ28761.1 - 4.9e-07 29.3 2.5 0.22 11.5 0.1 5.2 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.2 OAJ28761.1 - 0.00016 21.0 0.2 1.5 8.3 0.0 4.0 4 0 0 4 4 4 2 PPR repeat SelB-wing_2 PF09106.6 OAJ28761.1 - 0.033 14.1 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Elongation factor SelB, winged helix DUF2431 PF10354.4 OAJ28763.1 - 6.9e-31 107.4 0.0 1.9e-28 99.5 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) RVT_1 PF00078.22 OAJ28764.1 - 1e-22 80.5 0.0 1.7e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ28764.1 - 0.00063 19.3 0.1 0.0014 18.2 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase SET PF00856.23 OAJ28765.1 - 6.1e-22 78.6 0.0 5.2e-21 75.6 0.0 2.3 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 OAJ28765.1 - 1.1e-05 25.6 2.6 2.4e-05 24.5 1.8 1.6 1 0 0 1 1 1 1 Pre-SET motif PPR_2 PF13041.1 OAJ28766.1 - 5.1e-09 35.9 0.0 2.1e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 PPR repeat family IMS_C PF11799.3 OAJ28766.1 - 0.056 13.3 0.1 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain PPR_3 PF13812.1 OAJ28766.1 - 0.06 13.6 0.0 6.3 7.3 0.0 3.4 3 0 0 3 3 3 0 Pentatricopeptide repeat domain DUF3653 PF12375.3 OAJ28766.1 - 1.2 9.3 4.8 0.69 10.1 0.2 2.4 2 0 0 2 2 2 0 Phage protein Dus PF01207.12 OAJ28767.1 - 2.4e-47 161.2 0.0 6.3e-32 110.6 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 OAJ28767.1 - 1.7e-07 30.7 5.6 0.00072 19.1 0.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Apolipoprotein PF01442.13 OAJ28768.1 - 0.00013 21.6 12.3 0.00023 20.7 8.5 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain PHTB1_C PF14728.1 OAJ28768.1 - 0.00098 18.0 2.6 0.0012 17.6 1.8 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus OmpH PF03938.9 OAJ28768.1 - 0.0011 18.8 6.4 0.0022 17.9 4.5 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF724 PF05266.9 OAJ28768.1 - 0.0068 16.0 5.0 0.0092 15.6 1.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF724) Baculo_PEP_C PF04513.7 OAJ28768.1 - 0.0088 15.8 3.8 0.56 10.0 0.3 2.6 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus IMD PF08397.6 OAJ28768.1 - 0.014 14.7 0.7 0.019 14.2 0.5 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain Phage_GPO PF05929.6 OAJ28768.1 - 0.017 14.3 5.6 0.03 13.5 3.9 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase GAS PF13851.1 OAJ28768.1 - 0.02 14.0 5.0 0.034 13.3 3.5 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.15 OAJ28768.1 - 0.021 14.5 1.2 0.021 14.5 0.8 1.8 2 0 0 2 2 2 0 Prefoldin subunit IZUMO PF15005.1 OAJ28768.1 - 0.049 13.6 1.0 0.35 10.8 0.1 2.0 1 1 1 2 2 2 0 Izumo sperm-egg fusion Phage_Mu_Gam PF07352.7 OAJ28768.1 - 0.056 12.9 0.4 0.088 12.3 0.3 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein AF0941-like PF14591.1 OAJ28768.1 - 0.14 12.2 0.8 0.21 11.6 0.6 1.3 1 0 0 1 1 1 0 AF0941-like CENP-F_leu_zip PF10473.4 OAJ28768.1 - 0.17 11.7 6.4 0.55 10.0 4.3 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fzo_mitofusin PF04799.8 OAJ28768.1 - 0.18 11.1 8.4 3.3 7.0 0.2 2.6 1 1 1 2 2 2 0 fzo-like conserved region DUF342 PF03961.8 OAJ28768.1 - 0.19 10.1 0.6 0.24 9.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF842 PF05811.8 OAJ28768.1 - 0.35 10.3 6.0 0.39 10.1 2.2 2.2 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Cep57_MT_bd PF06657.8 OAJ28768.1 - 0.39 10.6 3.1 0.69 9.9 1.4 2.0 2 0 0 2 2 1 0 Centrosome microtubule-binding domain of Cep57 Spectrin PF00435.16 OAJ28768.1 - 0.39 11.0 7.5 4.8 7.5 5.2 2.2 1 1 0 1 1 1 0 Spectrin repeat FlxA PF14282.1 OAJ28768.1 - 0.4 10.6 7.3 1.5 8.7 4.8 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF1664 PF07889.7 OAJ28768.1 - 0.43 10.3 3.7 0.85 9.4 0.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Suppressor_APC PF11414.3 OAJ28768.1 - 1.8 8.4 11.9 1.5 8.6 0.0 2.8 2 1 1 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein DUF883 PF05957.8 OAJ28768.1 - 2.4 8.6 9.0 28 5.1 3.2 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Glyco_hydro_cc PF11790.3 OAJ28769.1 - 1e-50 172.4 2.3 1.4e-50 171.9 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Utp14 PF04615.8 OAJ28770.1 - 0.15 10.1 67.0 0.2 9.7 11.1 2.2 2 0 0 2 2 2 0 Utp14 protein PAT1 PF09770.4 OAJ28770.1 - 4 5.5 139.5 0.85 7.7 38.6 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 OAJ28770.1 - 4.8 5.3 46.1 2.9 6.0 8.5 2.2 2 0 0 2 2 2 0 Transmembrane protein Med15 PF09606.5 OAJ28770.1 - 6.8 4.7 173.5 0.41 8.8 63.4 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DEAD PF00270.24 OAJ28771.1 - 4.3e-16 58.8 0.0 2.2e-15 56.5 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ28771.1 - 0.033 14.0 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain PhoH PF02562.11 OAJ28771.1 - 0.23 10.6 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein LIP PF03583.9 OAJ28772.1 - 3.3e-41 141.3 0.3 1.2e-39 136.3 0.2 2.0 1 1 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 OAJ28772.1 - 0.00041 20.1 0.0 0.00078 19.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 OAJ28772.1 - 0.0083 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Cutinase DUF2920 PF11144.3 OAJ28772.1 - 0.043 12.8 0.0 0.29 10.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) NAD_binding_8 PF13450.1 OAJ28774.1 - 1.3e-07 31.5 0.0 3.7e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAJ28774.1 - 0.004 17.2 0.0 0.25 11.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ28774.1 - 0.0054 16.6 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAJ28774.1 - 0.026 13.4 0.6 0.061 12.1 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 OAJ28774.1 - 0.052 13.9 0.0 17 5.8 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MukE PF04288.8 OAJ28774.1 - 0.13 11.0 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 MukE-like family HI0933_like PF03486.9 OAJ28774.1 - 0.16 10.3 0.1 0.52 8.7 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Mito_carr PF00153.22 OAJ28775.1 - 1.5e-67 223.3 3.5 4.8e-23 80.6 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein PDCD2_C PF04194.8 OAJ28776.1 - 2.1e-24 85.9 0.4 1e-21 77.2 0.0 3.5 4 1 0 4 4 4 2 Programmed cell death protein 2, C-terminal putative domain NOA36 PF06524.7 OAJ28776.1 - 0.07 12.3 22.9 0.039 13.2 4.1 2.3 2 0 0 2 2 2 0 NOA36 protein Nucleoplasmin PF03066.10 OAJ28776.1 - 0.36 10.3 22.4 1.2 8.5 3.5 2.6 2 0 0 2 2 2 0 Nucleoplasmin DUF4611 PF15387.1 OAJ28776.1 - 1.7 8.8 19.5 1.2 9.3 4.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.7 OAJ28776.1 - 7.4 6.1 27.2 4.3 6.9 6.8 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.4 OAJ28776.1 - 9.7 4.7 31.8 1.7 7.2 4.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Glutaredoxin PF00462.19 OAJ28777.1 - 3.3e-18 65.4 0.0 5.6e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin F-box-like PF12937.2 OAJ28778.1 - 1.3e-05 24.8 0.1 2.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ28778.1 - 0.0013 18.2 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 OAJ28778.1 - 0.0037 16.9 0.6 0.0066 16.1 0.4 1.7 1 1 0 1 1 1 1 F-box-like domain E3_binding PF02817.12 OAJ28778.1 - 0.065 12.8 0.3 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 e3 binding domain Hamartin PF04388.7 OAJ28780.1 - 4.7e-17 61.9 0.0 4.7e-17 61.9 0.0 4.2 4 1 1 5 5 5 2 Hamartin protein Phlebovirus_NSM PF07246.6 OAJ28780.1 - 1.8 7.6 6.7 0.95 8.5 2.5 2.0 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M EF-hand_6 PF13405.1 OAJ28781.1 - 2.2e-09 36.3 2.4 0.00011 21.8 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 OAJ28781.1 - 1.4e-08 34.7 1.3 9.8e-07 28.8 0.9 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 OAJ28781.1 - 5.8e-08 31.4 5.9 0.00029 19.9 0.2 3.3 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 OAJ28781.1 - 0.0025 17.0 2.9 0.03 13.6 0.4 2.6 2 0 0 2 2 2 1 EF hand PRTP PF01366.13 OAJ28781.1 - 0.19 9.6 0.0 0.22 9.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein EF-hand_8 PF13833.1 OAJ28781.1 - 0.34 10.5 3.2 15 5.3 0.0 3.1 2 1 1 3 3 3 0 EF-hand domain pair Cellulase PF00150.13 OAJ28782.1 - 0.00039 19.7 0.0 0.00053 19.2 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) tRNA-synt_2 PF00152.15 OAJ28783.1 - 6.1e-69 232.3 0.0 8.6e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAJ28783.1 - 5.7e-11 42.1 0.0 1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RRP7 PF12923.2 OAJ28783.1 - 0.036 14.0 3.8 0.073 13.1 2.6 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) Nucleos_tra2_C PF07662.8 OAJ28784.1 - 4.9e-69 232.0 0.5 1e-68 230.9 0.4 1.6 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 OAJ28784.1 - 9.8e-13 48.2 3.9 9.8e-13 48.2 2.7 3.4 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 OAJ28784.1 - 2.2 8.2 16.2 3.5 7.5 5.9 3.4 2 1 0 2 2 2 0 Nucleoside recognition zf-DHHC PF01529.15 OAJ28785.1 - 3.6e-30 104.6 0.2 1.1e-29 103.0 0.1 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase UDPGT PF00201.13 OAJ28786.1 - 4.4e-08 32.1 0.0 1.2e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 OAJ28786.1 - 0.00044 20.0 0.2 0.0012 18.6 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_4_2 PF13477.1 OAJ28786.1 - 0.013 15.3 0.0 4 7.2 0.0 2.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like Ribosomal_S21 PF01165.15 OAJ28787.1 - 2.2e-11 43.0 3.9 4.4e-11 42.0 2.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 adh_short_C2 PF13561.1 OAJ28788.1 - 2.8e-30 105.8 0.0 3.4e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ28788.1 - 5.7e-19 68.6 0.8 2e-18 66.8 0.7 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAJ28788.1 - 2.6e-08 33.7 0.1 3.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 KR domain PA PF02225.17 OAJ28788.1 - 0.031 13.9 0.6 0.086 12.5 0.0 1.9 2 0 0 2 2 2 0 PA domain Saccharop_dh PF03435.13 OAJ28788.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase Put_Phosphatase PF06888.7 OAJ28789.1 - 2.1e-50 171.1 0.0 2.6e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase LRR_4 PF12799.2 OAJ28790.1 - 0.00082 18.9 2.9 5 6.8 0.0 4.9 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 OAJ28790.1 - 0.00096 18.9 12.9 9.8 6.5 0.7 7.6 7 1 0 7 7 7 1 Leucine Rich repeat LRR_8 PF13855.1 OAJ28790.1 - 0.001 18.7 1.6 2.5 7.9 0.0 4.7 4 1 0 4 4 4 1 Leucine rich repeat Vac7 PF12751.2 OAJ28790.1 - 0.098 11.4 7.5 0.19 10.5 5.2 1.4 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 LRR_7 PF13504.1 OAJ28790.1 - 0.16 12.2 3.4 49 4.7 0.0 5.2 5 0 0 5 5 5 0 Leucine rich repeat 3Beta_HSD PF01073.14 OAJ28791.1 - 3.5e-16 58.7 0.0 3.5e-15 55.4 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAJ28791.1 - 1.3e-14 54.2 0.1 3.3e-14 52.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ28791.1 - 6.6e-13 49.0 0.0 1.2e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 OAJ28791.1 - 4.9e-08 32.5 0.0 6.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 OAJ28791.1 - 8.6e-08 31.4 0.1 7.4e-07 28.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 OAJ28791.1 - 1.3e-05 24.2 0.0 2.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 OAJ28791.1 - 3.4e-05 23.8 0.5 0.00011 22.1 0.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ28791.1 - 0.0026 17.4 0.7 0.062 12.9 0.5 2.4 1 1 0 1 1 1 1 KR domain NAD_binding_2 PF03446.10 OAJ28791.1 - 0.0079 16.0 0.0 0.023 14.5 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 OAJ28791.1 - 0.031 13.6 0.1 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Complex1_LYR_2 PF13233.1 OAJ28792.1 - 1e-11 45.2 0.0 1.8e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 Complex1_LYR-like HTH_28 PF13518.1 OAJ28792.1 - 0.12 12.3 0.1 4 7.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Ribosomal_60s PF00428.14 OAJ28792.1 - 0.72 10.2 4.1 0.34 11.3 0.7 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein UFD1 PF03152.9 OAJ28793.1 - 4.1e-64 214.9 0.0 5.3e-64 214.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 OAJ28793.1 - 0.27 10.8 1.6 3 7.5 0.0 2.7 2 1 1 3 3 3 0 Cell division protein 48 (CDC48), domain 2 TRAM_LAG1_CLN8 PF03798.11 OAJ28794.1 - 4.8e-06 26.2 10.4 9.5e-06 25.2 7.2 1.5 1 0 0 1 1 1 1 TLC domain zf-LYAR PF08790.6 OAJ28796.1 - 3.5e-11 42.5 0.9 3.5e-11 42.5 0.7 1.8 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DUF3133 PF11331.3 OAJ28796.1 - 0.34 10.5 1.9 3.1 7.4 1.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) eIF3_subunit PF08597.5 OAJ28797.1 - 1e-41 143.1 23.4 1.3e-41 142.8 16.2 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PBP1_TM PF14812.1 OAJ28797.1 - 0.028 14.7 33.9 0.063 13.5 6.1 3.4 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3246 PF11596.3 OAJ28797.1 - 0.053 12.8 6.4 0.083 12.1 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Merozoite_SPAM PF07133.6 OAJ28797.1 - 0.38 10.6 17.3 0.035 14.0 7.8 1.9 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) zf-LYAR PF08790.6 OAJ28798.1 - 3.5e-11 42.5 0.9 3.5e-11 42.5 0.7 1.8 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DUF3133 PF11331.3 OAJ28798.1 - 0.34 10.5 1.9 3.1 7.4 1.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) DUF3541 PF12060.3 OAJ28799.1 - 0.021 14.1 0.1 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) Ion_trans PF00520.26 OAJ28799.1 - 0.14 11.4 0.4 0.14 11.3 0.3 1.1 1 0 0 1 1 1 0 Ion transport protein Peptidase_S8 PF00082.17 OAJ28800.1 - 1.2e-35 123.0 1.1 1.9e-35 122.3 0.7 1.3 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 OAJ28800.1 - 1.6e-08 34.9 0.0 3.2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) tRNA-synt_2b PF00587.20 OAJ28801.1 - 1.1e-43 148.7 0.0 2e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ28801.1 - 2.1e-16 59.6 0.2 4.7e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 OAJ28801.1 - 7.5e-13 48.1 0.0 1.6e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 OAJ28801.1 - 7.4e-11 41.7 0.0 1.8e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF502 PF04367.8 OAJ28801.1 - 0.03 14.0 0.1 0.17 11.6 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF502) DUF4316 PF14195.1 OAJ28801.1 - 0.89 9.6 3.2 29 4.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) eIF3_subunit PF08597.5 OAJ28802.1 - 1e-41 143.1 23.4 1.3e-41 142.8 16.2 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PBP1_TM PF14812.1 OAJ28802.1 - 0.028 14.7 33.9 0.063 13.5 6.1 3.4 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3246 PF11596.3 OAJ28802.1 - 0.053 12.8 6.4 0.083 12.1 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Merozoite_SPAM PF07133.6 OAJ28802.1 - 0.38 10.6 17.3 0.035 14.0 7.8 1.9 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) NAD_binding_10 PF13460.1 OAJ28803.1 - 1.1e-17 64.6 0.0 2.1e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 OAJ28803.1 - 9.1e-11 41.4 0.0 1.2e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 OAJ28803.1 - 2.1e-10 40.4 0.0 4.7e-10 39.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAJ28803.1 - 2.4e-10 39.5 0.0 6.6e-10 38.1 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 OAJ28803.1 - 3.6e-08 32.6 0.0 4.1e-06 25.9 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 OAJ28803.1 - 7.7e-08 31.5 0.2 0.0013 17.6 0.1 3.0 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 OAJ28803.1 - 0.0023 16.9 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 OAJ28803.1 - 0.0029 17.5 0.0 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAJ28803.1 - 0.017 14.7 0.0 0.22 11.1 0.0 2.3 2 0 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.10 OAJ28803.1 - 0.025 13.4 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Nt_Gln_amidase PF09764.4 OAJ28804.1 - 2e-26 92.3 0.7 2.3e-08 33.5 0.0 4.8 4 1 0 4 4 4 4 N-terminal glutamine amidase PrmA PF06325.8 OAJ28805.1 - 1.1e-09 37.9 0.0 1.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 OAJ28805.1 - 4.4e-06 26.3 0.0 8.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ28805.1 - 1.2e-05 25.8 0.0 2.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ28805.1 - 1.5e-05 24.9 0.1 5.8e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ28805.1 - 2.6e-05 23.9 0.0 5.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ28805.1 - 0.00037 19.9 0.0 0.00069 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 OAJ28805.1 - 0.00072 20.0 0.0 0.0017 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ28805.1 - 0.0012 19.1 0.0 0.003 17.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 OAJ28805.1 - 0.0091 14.9 0.0 0.016 14.1 0.0 1.4 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.6 OAJ28805.1 - 0.045 12.4 0.0 0.072 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.10 OAJ28805.1 - 0.054 12.8 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_12 PF08242.7 OAJ28805.1 - 0.056 13.9 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain SDA1 PF05285.7 OAJ28805.1 - 0.22 10.7 4.9 0.35 10.1 3.4 1.3 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.4 OAJ28805.1 - 9.3 4.8 16.5 22 3.6 11.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Arginase PF00491.16 OAJ28806.1 - 3.7e-74 249.5 0.0 4.3e-74 249.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family COX6B PF02297.12 OAJ28807.1 - 5e-23 80.8 0.2 6.3e-23 80.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb SR-25 PF10500.4 OAJ28807.1 - 1.6 8.1 6.4 0.44 9.9 1.2 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Glyco_hydro_9 PF00759.14 OAJ28808.1 - 3.2e-38 131.7 2.5 7.2e-31 107.5 0.1 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 9 PP2C PF00481.16 OAJ28808.1 - 2.9e-10 39.9 0.0 4.4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Aconitase PF00330.15 OAJ28809.1 - 3.8e-180 599.3 0.0 4.7e-180 599.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAJ28809.1 - 6.6e-44 149.1 0.0 1.3e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain RNase_H PF00075.19 OAJ28810.1 - 2.3e-18 66.7 0.0 3.9e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 OAJ28810.1 - 0.012 15.9 0.3 0.027 14.7 0.2 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_1 PF00078.22 OAJ28811.1 - 1.6e-24 86.4 0.0 2.8e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ28811.1 - 1.1e-18 66.9 0.1 2.1e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ28811.1 - 0.00011 22.2 0.2 0.00025 21.0 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YPEB PF14620.1 OAJ28813.1 - 0.047 12.7 0.6 0.091 11.7 0.2 1.5 2 0 0 2 2 2 0 YpeB sporulation HAUS-augmin3 PF14932.1 OAJ28813.1 - 0.12 11.5 3.5 0.21 10.7 0.3 2.2 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 DEAD PF00270.24 OAJ28814.1 - 7.5e-37 126.4 0.3 2.3e-36 124.8 0.2 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ28814.1 - 7.6e-19 67.3 0.0 2e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 OAJ28814.1 - 3.5e-14 52.0 0.0 7.1e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 OAJ28814.1 - 4.5e-06 26.6 0.0 2.6e-05 24.1 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4137 PF13593.1 OAJ28814.1 - 0.0068 15.5 0.1 0.01 14.9 0.1 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) AAA_22 PF13401.1 OAJ28814.1 - 0.036 14.2 1.2 0.47 10.5 0.9 2.4 1 1 0 1 1 1 0 AAA domain SR-25 PF10500.4 OAJ28814.1 - 0.44 9.9 20.1 0.023 14.1 9.7 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Tombus_P33 PF08500.5 OAJ28814.1 - 6.3 6.5 7.3 14 5.4 4.6 1.8 1 1 0 1 1 1 0 Tombusvirus p33 CDC45 PF02724.9 OAJ28814.1 - 6.3 4.6 15.4 12 3.8 10.6 1.3 1 0 0 1 1 1 0 CDC45-like protein RAP1 PF07218.6 OAJ28815.1 - 0.024 12.7 14.4 0.029 12.4 10.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Hamartin PF04388.7 OAJ28815.1 - 0.28 9.8 19.8 0.26 9.8 13.7 1.0 1 0 0 1 1 1 0 Hamartin protein DUF605 PF04652.11 OAJ28815.1 - 0.41 10.0 17.5 0.45 9.8 12.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF566 PF04484.7 OAJ28815.1 - 1.2 8.5 19.2 1.3 8.4 13.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Pol_alpha_B_N PF08418.5 OAJ28815.1 - 8.9 5.7 23.3 14 5.1 16.2 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Mito_fiss_reg PF05308.6 OAJ28816.1 - 1 8.6 3.6 1.1 8.5 2.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator Omega-toxin PF06357.6 OAJ28816.1 - 1.5 8.4 5.7 0.11 12.0 0.6 1.7 2 0 0 2 2 2 0 Omega-atracotoxin EB PF01683.13 OAJ28816.1 - 3 7.9 7.2 7.3 6.7 0.2 1.6 1 1 1 2 2 2 0 EB module SSP160 PF06933.6 OAJ28816.1 - 4.9 5.0 17.2 5.3 4.8 11.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 OAJ28816.1 - 9 3.9 7.1 8.6 3.9 4.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1688 PF07958.6 OAJ28817.1 - 6.6e-143 476.2 0.0 2.5e-92 309.5 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1688) Rb_C PF08934.5 OAJ28818.1 - 0.08 12.5 0.6 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Rb C-terminal domain Mito_carr PF00153.22 OAJ28819.1 - 3e-62 206.3 4.6 5e-21 74.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TSA PF03249.8 OAJ28820.1 - 0.052 12.0 5.5 0.077 11.5 3.8 1.2 1 0 0 1 1 1 0 Type specific antigen Macoilin PF09726.4 OAJ28820.1 - 0.37 9.0 6.4 0.44 8.7 4.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Dmrt1 PF12374.3 OAJ28820.1 - 9.9 6.6 21.5 2.3 8.6 7.4 2.4 1 1 1 2 2 2 0 Double-sex mab3 related transcription factor 1 Actin PF00022.14 OAJ28821.1 - 4.3e-30 104.4 0.0 2.2e-19 69.1 0.0 3.6 3 1 0 3 3 3 2 Actin Sporozoite_P67 PF05642.6 OAJ28821.1 - 0.87 7.3 9.2 0.15 9.9 3.3 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Nitroreductase PF00881.19 OAJ28822.1 - 2.2e-11 43.8 0.0 2.7e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family YodL PF14191.1 OAJ28822.1 - 0.043 14.3 0.0 0.091 13.2 0.0 1.5 1 0 0 1 1 1 0 YodL-like HK PF02110.10 OAJ28824.1 - 2e-58 197.4 8.5 6.8e-57 192.4 4.3 2.5 2 1 0 3 3 3 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 OAJ28824.1 - 1.1e-43 148.4 0.1 1.6e-42 144.6 0.0 2.2 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 OAJ28824.1 - 1.2e-07 31.1 0.8 2e-07 30.4 0.6 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Polysacc_deac_1 PF01522.16 OAJ28825.1 - 2.5e-23 82.0 0.0 4.7e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase nec1 PF10379.4 OAJ28825.1 - 0.0027 16.9 0.0 0.0058 15.9 0.0 1.7 1 0 0 1 1 1 1 Virulence protein nec1 Lipase_3 PF01764.20 OAJ28827.1 - 3.8e-13 49.2 0.0 7.7e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) FAM60A PF15396.1 OAJ28827.1 - 7.2 6.2 5.7 5.3 6.7 0.0 2.6 2 1 0 2 2 2 0 Protein Family FAM60A Pex24p PF06398.6 OAJ28828.1 - 3.2e-32 111.7 0.1 2.7e-25 88.9 0.0 2.4 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin RNA_pol_Rpb1_1 PF04997.7 OAJ28829.1 - 3.9e-88 295.9 0.0 6e-88 295.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 OAJ28829.1 - 4.2e-64 215.4 0.0 7.2e-64 214.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 OAJ28829.1 - 4.8e-38 130.3 0.0 9.3e-38 129.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_5 PF04998.12 OAJ28829.1 - 2e-30 105.9 0.0 3.5e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.12 OAJ28829.1 - 9e-28 96.1 0.0 2e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Zn_Tnp_IS1 PF03811.8 OAJ28829.1 - 0.053 13.0 0.1 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 InsA N-terminal domain Use1 PF09753.4 OAJ28830.1 - 0.22 10.9 7.6 0.17 11.2 3.6 2.1 2 0 0 2 2 2 0 Membrane fusion protein Use1 Nexin_C PF08628.7 OAJ28830.1 - 0.96 9.5 4.1 7.5 6.6 0.1 2.9 2 0 0 2 2 2 0 Sorting nexin C terminal EHN PF06441.7 OAJ28832.1 - 2.9e-23 81.9 0.1 5.6e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 OAJ28832.1 - 1.2e-10 41.3 0.0 2.2e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ28832.1 - 2.1e-08 34.3 3.6 2.1e-08 34.3 2.5 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family NAD_binding_10 PF13460.1 OAJ28832.1 - 4.4e-06 26.8 0.0 6.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Mg_trans_NIPA PF05653.9 OAJ28833.1 - 1.8e-07 30.4 0.9 2.1e-07 30.1 0.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA Yip1 PF04893.12 OAJ28833.1 - 0.034 13.6 6.1 0.073 12.5 4.1 1.6 1 1 0 1 1 1 0 Yip1 domain Cmc1 PF08583.5 OAJ28834.1 - 1.5e-17 63.0 1.3 2.2e-17 62.5 0.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 OAJ28834.1 - 0.081 12.9 0.4 14 5.7 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 OAJ28834.1 - 0.91 9.5 3.2 5.1 7.1 2.3 2.2 1 1 1 2 2 2 0 CHCH domain DEAD PF00270.24 OAJ28835.1 - 2.9e-28 98.4 0.0 4.9e-13 48.9 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ28835.1 - 9.9e-21 73.4 0.1 5.4e-20 71.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ28835.1 - 0.00066 19.5 0.2 0.0057 16.5 0.0 2.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DJ-1_PfpI PF01965.19 OAJ28836.1 - 9.5e-26 90.0 0.0 1.5e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 OAJ28836.1 - 5.3e-17 61.0 0.0 9.7e-17 60.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family MFS_1 PF07690.11 OAJ28837.1 - 4e-23 81.7 29.6 9.7e-18 63.9 7.8 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 OAJ28837.1 - 2.5e-08 32.8 17.4 6e-06 25.0 2.6 2.7 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_3 PF05977.8 OAJ28837.1 - 0.16 10.0 0.0 0.16 10.0 0.0 2.8 3 0 0 3 3 3 0 Transmembrane secretion effector TAP42 PF04177.7 OAJ28837.1 - 0.33 9.8 4.0 0.14 11.0 0.8 1.7 2 0 0 2 2 2 0 TAP42-like family LRR_4 PF12799.2 OAJ28838.1 - 2.2e-14 52.6 8.9 1.3e-05 24.7 2.0 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ28838.1 - 1.3e-13 50.4 10.3 1.7e-08 34.1 3.4 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 OAJ28838.1 - 1.3e-05 24.5 13.5 0.82 9.9 0.1 5.7 4 1 1 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 OAJ28838.1 - 0.37 11.1 17.1 8.8 7.0 0.2 5.6 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 OAJ28838.1 - 2.1 8.6 10.4 11 6.3 0.1 4.5 4 1 1 5 5 5 0 Leucine Rich repeat Sec6 PF06046.8 OAJ28839.1 - 4.4e-143 477.3 0.0 6.2e-143 476.8 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 OAJ28839.1 - 0.00054 18.8 3.5 0.0035 16.1 0.8 2.8 3 0 0 3 3 3 1 Vps53-like, N-terminal MutS_III PF05192.13 OAJ28839.1 - 0.0014 18.4 0.0 0.012 15.4 0.0 2.6 1 1 0 2 2 2 1 MutS domain III Ribosomal_60s PF00428.14 OAJ28840.1 - 6.8e-28 96.9 10.5 8.2e-28 96.6 7.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sigma70_r1_1 PF03979.9 OAJ28840.1 - 0.35 10.8 0.0 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 DUF3138 PF11336.3 OAJ28840.1 - 0.37 8.9 1.9 0.39 8.8 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_S19 PF00203.16 OAJ28841.1 - 7.1e-32 108.8 0.2 1e-31 108.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 OAJ28841.1 - 0.033 14.0 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein FliH TPR_11 PF13414.1 OAJ28842.1 - 1.8e-12 46.7 1.2 2.6e-06 26.9 0.2 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 OAJ28842.1 - 3.3e-07 29.7 0.7 8.7e-05 22.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ28842.1 - 2.4e-06 26.9 0.9 0.00017 21.0 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ28842.1 - 0.0028 17.3 0.0 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ28842.1 - 0.018 14.8 0.0 0.018 14.8 0.0 2.7 2 1 2 4 4 4 0 Tetratricopeptide repeat YppG PF14179.1 OAJ28842.1 - 9.5 6.8 7.5 17 6.0 5.2 1.4 1 0 0 1 1 1 0 YppG-like protein TPR_19 PF14559.1 OAJ28843.1 - 3.8e-08 33.5 0.9 0.0029 17.9 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ28843.1 - 5.2e-07 30.1 3.3 0.006 17.2 0.0 4.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ28843.1 - 2.5e-05 24.5 5.5 0.18 12.5 0.0 5.2 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ28843.1 - 4.3e-05 23.6 0.1 0.0045 17.3 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ28843.1 - 7.7e-05 22.3 0.0 0.011 15.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ28843.1 - 0.00017 21.1 0.3 0.029 14.0 0.0 2.9 3 1 0 3 3 3 1 TPR repeat TPR_12 PF13424.1 OAJ28843.1 - 0.00067 19.5 1.8 0.1 12.5 0.0 3.7 2 2 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ28843.1 - 0.003 17.6 0.0 0.55 10.4 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 OAJ28843.1 - 0.011 15.4 0.0 1.7 8.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ28843.1 - 0.014 15.7 0.1 1.2 9.7 0.0 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.2 OAJ28843.1 - 0.022 14.7 0.5 5.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_10 PF13374.1 OAJ28843.1 - 0.042 13.7 0.4 0.042 13.7 0.3 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ28843.1 - 0.11 12.1 0.0 4.6 7.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Thioredoxin PF00085.15 OAJ28845.1 - 3e-23 81.4 0.0 1.5e-22 79.2 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 OAJ28845.1 - 6.1e-05 23.0 0.0 0.0002 21.3 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ28845.1 - 0.00026 21.1 0.1 0.00026 21.1 0.0 3.1 2 2 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.16 OAJ28845.1 - 0.004 16.8 0.2 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 OAJ28845.1 - 0.0077 16.2 0.0 0.0077 16.2 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_6 PF13848.1 OAJ28845.1 - 0.038 13.7 0.0 0.33 10.7 0.0 2.3 1 1 0 1 1 1 0 Thioredoxin-like domain GHMP_kinases_N PF00288.21 OAJ28846.1 - 1.1e-13 51.0 0.2 5.1e-13 48.8 0.1 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 OAJ28846.1 - 0.0013 18.8 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal RNA_pol_Rpb1_5 PF04998.12 OAJ28847.1 - 1.5e-12 47.3 0.0 3e-12 46.3 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Daxx PF03344.10 OAJ28847.1 - 1.2 7.5 10.8 1.4 7.3 7.5 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 OAJ28847.1 - 6.4 4.5 19.3 8.2 4.2 13.4 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 OAJ28847.1 - 7.1 4.8 20.3 8.6 4.6 14.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 OAJ28847.1 - 8.8 4.2 18.4 12 3.7 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Phage_integrase PF00589.17 OAJ28849.1 - 6.6e-06 25.8 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family RCC1 PF00415.13 OAJ28850.1 - 5.6e-15 55.2 6.6 0.0055 16.8 0.0 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.1 OAJ28850.1 - 7.3e-11 41.9 0.6 6.4e-08 32.6 0.2 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) BTB PF00651.26 OAJ28850.1 - 1.4e-09 37.8 0.0 9.5e-05 22.3 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 OAJ28850.1 - 8.9e-08 32.4 0.4 0.00031 21.1 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ28850.1 - 3.2e-05 23.7 1.4 0.4 11.0 0.1 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 OAJ28850.1 - 3.3e-05 24.1 0.2 0.00019 21.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.1 OAJ28850.1 - 0.00064 19.2 15.6 0.0023 17.5 0.0 5.5 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat Ank PF00023.25 OAJ28850.1 - 0.0029 17.3 1.6 0.011 15.4 0.2 2.6 2 0 0 2 2 2 1 Ankyrin repeat AMP-binding PF00501.23 OAJ28851.1 - 4.4e-72 242.7 0.0 5.6e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ28851.1 - 6.1e-08 33.4 0.2 1.4e-07 32.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ig_Tie2_1 PF10430.4 OAJ28851.1 - 0.038 14.3 0.0 0.087 13.1 0.0 1.5 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 Prp19_bind PF06991.6 OAJ28852.1 - 4.8e-59 199.9 23.3 4.8e-59 199.9 16.1 2.0 2 0 0 2 2 2 1 Splicing factor, Prp19-binding domain zf-CCHC_2 PF13696.1 OAJ28852.1 - 0.2 11.1 0.8 0.46 10.0 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 OAJ28852.1 - 0.31 11.0 1.9 0.9 9.5 1.3 1.8 1 1 0 1 1 1 0 Zinc knuckle THF_DHG_CYH PF00763.18 OAJ28853.1 - 9.5e-16 57.8 0.0 1.1e-06 28.6 0.0 2.3 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 OAJ28853.1 - 1.4e-13 50.2 0.1 3.9e-08 32.5 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.17 OAJ28853.1 - 0.039 12.7 0.4 0.057 12.2 0.3 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Shikimate_DH PF01488.15 OAJ28853.1 - 0.064 13.3 0.6 0.98 9.5 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase VKG_Carbox PF05090.9 OAJ28853.1 - 0.11 11.2 0.1 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase DUF2420 PF10336.4 OAJ28854.1 - 1.4e-08 34.2 0.0 2.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) NAD_binding_11 PF14833.1 OAJ28855.1 - 1.5e-14 54.1 0.0 2.4e-14 53.4 0.0 1.4 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Pyridoxal_deC PF00282.14 OAJ28856.1 - 1.3e-46 158.7 0.0 1.5e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain AJAP1_PANP_C PF15298.1 OAJ28859.1 - 0.17 11.7 2.1 0.17 11.7 1.4 1.0 1 0 0 1 1 1 0 AJAP1/PANP C-terminus PCI PF01399.22 OAJ28860.1 - 9.2e-20 70.9 0.1 3.5e-19 69.0 0.0 2.1 1 0 0 1 1 1 1 PCI domain TPR_16 PF13432.1 OAJ28860.1 - 0.00011 22.8 17.7 0.091 13.4 4.4 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ28860.1 - 0.0017 17.9 9.8 0.21 11.2 1.2 3.7 3 0 0 3 3 3 2 TPR repeat DUF627 PF04781.7 OAJ28860.1 - 0.004 16.7 1.5 2.8 7.5 0.1 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF627) TPR_7 PF13176.1 OAJ28860.1 - 0.055 13.2 1.0 6.2 6.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ28860.1 - 0.089 13.1 13.9 0.24 11.7 1.2 4.6 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.4 OAJ28860.1 - 0.11 12.4 17.7 1.2 9.0 5.7 3.7 2 1 1 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 OAJ28860.1 - 0.11 12.5 4.9 4.4 7.5 0.1 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.1 OAJ28860.1 - 0.15 12.2 6.2 0.35 11.0 0.5 3.6 3 1 2 5 5 5 0 Alkyl sulfatase dimerisation TPR_6 PF13174.1 OAJ28860.1 - 0.15 12.5 8.4 13 6.5 0.2 5.1 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ28860.1 - 0.34 11.6 16.1 0.73 10.6 1.4 5.2 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ28860.1 - 6.6 6.9 13.1 54 4.0 0.1 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.4 OAJ28861.1 - 2e-52 177.1 1.6 2.8e-52 176.6 1.1 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 OAJ28861.1 - 3.1e-14 53.1 0.0 7.4e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 PCI domain SAC3_GANP PF03399.11 OAJ28861.1 - 0.0098 15.4 0.7 0.015 14.8 0.1 1.6 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Selenoprotein_S PF06936.6 OAJ28861.1 - 0.029 13.9 0.3 0.79 9.2 0.2 2.2 2 0 0 2 2 2 0 Selenoprotein S (SelS) RVT_1 PF00078.22 OAJ28862.1 - 7.1e-16 58.2 0.0 1.4e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 OAJ28862.1 - 0.0011 18.7 1.9 0.0011 18.7 1.3 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ28862.1 - 3.5 7.3 6.7 0.36 10.5 1.2 1.9 2 0 0 2 2 2 0 Zinc knuckle Pribosyltran PF00156.22 OAJ28863.1 - 7e-17 61.3 0.2 9.8e-17 60.8 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 OAJ28863.1 - 0.0039 16.4 0.0 0.0052 16.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase zf-CCHC PF00098.18 OAJ28864.1 - 4.4e-06 26.3 2.4 4.4e-06 26.3 1.6 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ28864.1 - 0.05 13.1 0.3 0.092 12.2 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 OAJ28864.1 - 0.088 12.3 1.7 0.18 11.2 1.2 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.1 OAJ28864.1 - 0.12 12.0 0.7 0.22 11.2 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle CDRN PF05174.7 OAJ28864.1 - 0.13 11.7 0.1 0.31 10.5 0.1 1.6 1 0 0 1 1 1 0 Cysteine-rich D. radiodurans N terminus RVT_2 PF07727.9 OAJ28865.1 - 5.4e-85 284.2 0.0 7.5e-85 283.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ28865.1 - 6.9e-20 71.3 0.1 1.8e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ28865.1 - 0.00057 19.3 0.2 0.0093 15.4 0.3 2.7 2 1 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ28865.1 - 0.053 12.8 0.0 0.098 11.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AMP-binding PF00501.23 OAJ28866.1 - 1.4e-81 274.0 0.0 1.7e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ28866.1 - 3.7e-10 40.5 0.0 9.9e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TFIIS_M PF07500.9 OAJ28868.1 - 9.9e-23 80.4 1.6 1.6e-22 79.7 0.1 2.0 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 OAJ28868.1 - 7e-19 67.1 7.8 1.2e-18 66.4 5.4 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 OAJ28868.1 - 1.6e-15 56.3 0.4 1.6e-15 56.3 0.3 1.7 2 0 0 2 2 2 1 TFIIS helical bundle-like domain TF_Zn_Ribbon PF08271.7 OAJ28868.1 - 0.014 14.6 0.5 0.025 13.8 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 OAJ28868.1 - 0.73 9.4 4.7 0.3 10.7 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 OAJ28868.1 - 1.2 8.8 4.8 0.54 10.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain SLT_L PF14718.1 OAJ28869.1 - 0.077 12.8 0.6 0.6 9.9 0.2 2.3 1 1 1 2 2 2 0 Soluble lytic murein transglycosylase L domain DUF4482 PF14818.1 OAJ28870.1 - 0.035 14.7 1.7 0.035 14.7 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Phage_integrase PF00589.17 OAJ28871.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DNA_pol_viral_C PF00336.13 OAJ28871.1 - 0.023 13.9 0.2 0.049 12.8 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Ins_beta PF03488.9 OAJ28872.1 - 0.064 13.0 0.8 0.064 13.0 0.6 2.2 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Pyridox_ox_2 PF12900.2 OAJ28874.1 - 1.4e-36 125.4 0.0 1.8e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DEAD PF00270.24 OAJ28875.1 - 3.3e-40 137.3 0.7 8.9e-40 135.9 0.5 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Pyridox_ox_2 PF12900.2 OAJ28875.1 - 1.3e-15 57.4 0.1 2.5e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Helicase_C PF00271.26 OAJ28875.1 - 2.2e-08 33.8 0.1 8.8e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 OAJ28875.1 - 0.00017 21.2 0.2 0.00049 19.7 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 OAJ28875.1 - 0.00091 19.1 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 OAJ28875.1 - 0.022 14.8 0.1 0.059 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 OAJ28875.1 - 0.066 12.7 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 OAJ28875.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain CMS1 PF14617.1 OAJ28875.1 - 0.073 12.1 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.9 OAJ28875.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Helicase UvrD-helicase PF00580.16 OAJ28875.1 - 0.11 11.7 0.1 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Cutinase PF01083.17 OAJ28877.1 - 8e-29 100.6 0.0 9.8e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 OAJ28877.1 - 0.00078 18.9 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Lipase_3 PF01764.20 OAJ28877.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.15 OAJ28877.1 - 0.016 14.7 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold ECR1_N PF14382.1 OAJ28877.1 - 0.02 14.1 0.0 0.057 12.7 0.0 1.8 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region Abhydrolase_8 PF06259.7 OAJ28877.1 - 0.037 13.5 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase LIP PF03583.9 OAJ28877.1 - 0.06 12.5 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase Cutinase PF01083.17 OAJ28878.1 - 3.3e-21 75.8 0.0 4.2e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Cutinase Cutinase PF01083.17 OAJ28879.1 - 8.6e-27 94.0 0.1 1.1e-26 93.7 0.1 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ28879.1 - 0.002 17.7 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 OAJ28879.1 - 0.044 13.2 0.1 0.15 11.4 0.0 1.7 1 1 1 2 2 2 0 Serine hydrolase (FSH1) PE-PPE PF08237.6 OAJ28879.1 - 0.093 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain GEMIN8 PF15348.1 OAJ28880.1 - 0.026 14.5 2.1 0.071 13.1 1.5 1.7 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Transposase_21 PF02992.9 OAJ28881.1 - 2.1e-19 69.5 0.0 6e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Transposase family tnp2 Spore_coat_CotO PF14153.1 OAJ28881.1 - 0.0067 15.8 5.0 0.013 14.9 3.4 1.4 1 0 0 1 1 1 1 Spore coat protein CotO BUD22 PF09073.5 OAJ28881.1 - 0.05 12.6 16.6 0.089 11.8 11.5 1.3 1 0 0 1 1 1 0 BUD22 Ycf1 PF05758.7 OAJ28881.1 - 0.15 9.7 0.5 0.19 9.4 0.4 1.1 1 0 0 1 1 1 0 Ycf1 Radial_spoke PF04712.7 OAJ28881.1 - 0.19 10.4 9.0 0.3 9.7 6.3 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Atrophin-1 PF03154.10 OAJ28881.1 - 0.67 8.0 6.9 0.99 7.4 4.8 1.2 1 0 0 1 1 1 0 Atrophin-1 family Menin PF05053.8 OAJ28881.1 - 1.6 6.8 4.1 3.7 5.6 3.0 1.4 2 0 0 2 2 2 0 Menin TRAP_alpha PF03896.11 OAJ28881.1 - 1.7 7.5 9.6 3.5 6.5 6.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Clathrin PF00637.15 OAJ28882.1 - 6e-180 590.0 30.6 3.5e-31 107.7 0.7 8.0 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 OAJ28882.1 - 8.5e-31 105.6 0.1 3.9e-30 103.5 0.1 2.3 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.5 OAJ28882.1 - 2.7e-07 29.4 0.2 2.7e-07 29.4 0.1 1.8 2 0 0 2 2 2 1 Clathrin, heavy-chain linker Clathrin_propel PF01394.15 OAJ28882.1 - 5.6e-06 26.2 0.0 0.03 14.6 0.0 2.6 2 0 0 2 2 2 2 Clathrin propeller repeat Coatomer_WDAD PF04053.9 OAJ28882.1 - 0.0011 17.7 3.4 1.3 7.7 0.0 3.9 4 0 0 4 4 4 2 Coatomer WD associated region TPR_7 PF13176.1 OAJ28882.1 - 0.0019 17.8 8.3 27 4.8 0.0 6.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ28882.1 - 0.0032 17.1 1.3 34 4.5 0.0 5.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ28882.1 - 0.0074 16.1 14.8 5.2 7.2 0.1 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ28882.1 - 0.066 13.4 2.6 26 5.3 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ28882.1 - 0.15 11.6 14.7 8 6.2 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ28882.1 - 0.16 11.9 16.2 23 5.0 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ28882.1 - 0.27 10.8 13.3 4.3 7.0 0.1 6.1 6 1 0 6 6 5 0 TPR repeat TPR_14 PF13428.1 OAJ28882.1 - 1.2 9.9 21.7 43 5.1 0.1 10.2 12 1 1 13 13 12 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.19 OAJ28883.1 - 4.5e-14 52.2 0.0 6.9e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAJ28883.1 - 0.00017 21.7 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAJ28883.1 - 0.00018 21.5 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ28883.1 - 0.0024 17.5 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 OAJ28883.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DnaJ PF00226.26 OAJ28884.1 - 1.2e-06 28.1 0.1 1.7e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 OAJ28884.1 - 0.00014 21.6 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Pam16 Aminotran_1_2 PF00155.16 OAJ28887.1 - 1.5e-15 57.0 0.0 1.9e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 OAJ28887.1 - 6.8e-06 24.8 0.0 9.6e-06 24.3 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Glutaredoxin PF00462.19 OAJ28888.1 - 2.1e-18 66.0 0.0 2.8e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 OAJ28888.1 - 0.00058 20.0 0.1 0.0021 18.2 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.9 OAJ28888.1 - 0.001 19.2 0.0 0.0012 19.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 OAJ28888.1 - 0.0018 18.0 0.1 0.0026 17.5 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin domain DUF953 PF06110.6 OAJ28888.1 - 0.0064 15.9 0.0 0.0071 15.7 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 OAJ28888.1 - 0.017 14.7 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin GST_N_3 PF13417.1 OAJ28888.1 - 0.028 14.6 0.0 0.038 14.2 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.1 OAJ28888.1 - 0.033 14.1 0.2 4.7 7.1 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin DSBA PF01323.15 OAJ28888.1 - 0.034 13.6 0.1 0.35 10.3 0.1 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_7 PF13899.1 OAJ28888.1 - 0.083 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like TusA PF01206.12 OAJ28888.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.4 1 1 0 1 1 1 0 Sulfurtransferase TusA Zn_ribbon_2 PF12674.2 OAJ28888.1 - 0.096 13.0 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative zinc ribbon domain Myb_DNA-binding PF00249.26 OAJ28889.1 - 6.7e-32 109.3 4.7 1.4e-10 41.0 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ28889.1 - 5.3e-31 106.4 0.3 1.4e-12 47.4 0.0 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 OAJ28889.1 - 0.015 15.1 3.5 12 5.8 0.1 3.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain GntR PF00392.16 OAJ28889.1 - 0.16 11.4 0.0 4.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Myb_DNA-bind_4 PF13837.1 OAJ28889.1 - 6.8 6.9 7.7 17 5.5 0.1 3.3 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain WD40 PF00400.27 OAJ28890.1 - 2.9e-35 118.8 0.5 1.5e-08 34.1 0.0 7.5 6 1 1 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 OAJ28890.1 - 0.00033 18.9 0.2 0.0005 18.3 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 OAJ28890.1 - 0.00066 19.2 0.6 0.0015 18.0 0.4 1.7 1 1 0 1 1 1 1 PQQ-like domain DPBB_1 PF03330.13 OAJ28891.1 - 6.1e-06 26.1 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel FNIP_N PF14636.1 OAJ28891.1 - 1.1 9.7 9.1 1.8 9.0 6.3 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Mucin PF01456.12 OAJ28891.1 - 3.6 7.3 18.4 9.2 6.0 12.7 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein V-SNARE_C PF12352.3 OAJ28892.1 - 9.2e-18 64.0 7.6 2e-17 63.0 4.9 1.9 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 OAJ28892.1 - 1.8e-15 56.8 12.1 2.8e-15 56.2 2.3 3.1 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Prominin PF05478.6 OAJ28892.1 - 0.0051 14.4 1.4 0.027 12.0 0.0 2.1 2 1 0 2 2 2 1 Prominin Fusion_gly PF00523.13 OAJ28892.1 - 0.0066 14.5 0.2 0.0066 14.5 0.1 1.5 2 0 0 2 2 2 1 Fusion glycoprotein F0 PNK3P PF08645.6 OAJ28892.1 - 0.013 14.8 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Sec20 PF03908.8 OAJ28892.1 - 0.059 13.0 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 Sec20 YqjK PF13997.1 OAJ28892.1 - 0.075 13.2 0.6 0.075 13.2 0.4 2.1 2 0 0 2 2 2 0 YqjK-like protein DUF912 PF06024.7 OAJ28892.1 - 0.11 12.5 1.1 0.74 9.8 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2939 PF11159.3 OAJ28892.1 - 0.13 12.4 0.8 0.27 11.4 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) ApoLp-III PF07464.6 OAJ28892.1 - 0.18 11.8 10.1 1.5 8.8 0.2 2.8 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Fib_alpha PF08702.5 OAJ28892.1 - 0.28 11.2 5.7 0.8 9.8 1.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Sec8_exocyst PF04048.9 OAJ28892.1 - 0.33 10.5 3.7 0.67 9.5 0.1 2.5 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Sigma_reg_N PF13800.1 OAJ28892.1 - 0.45 10.5 3.6 0.86 9.6 2.5 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal ODV-E18 PF10717.4 OAJ28892.1 - 1.9 7.9 4.6 0.81 9.1 0.3 2.2 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Methyltransf_23 PF13489.1 OAJ28893.1 - 7e-18 64.8 1.5 1.8e-17 63.5 1.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ28893.1 - 5.5e-16 58.8 0.1 8.8e-15 54.9 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ28893.1 - 1.5e-15 57.0 0.0 7.2e-13 48.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ28893.1 - 8.9e-15 55.2 0.0 2.2e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ28893.1 - 2.7e-13 50.2 1.8 2.1e-12 47.3 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ28893.1 - 3.1e-09 37.0 0.1 3.1e-09 37.0 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ28893.1 - 4.5e-08 33.1 0.5 1.4e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ28893.1 - 2.6e-06 26.7 0.1 0.014 14.4 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family MTS PF05175.9 OAJ28893.1 - 0.00039 19.8 5.8 0.0024 17.2 0.1 3.3 1 1 2 3 3 3 1 Methyltransferase small domain NodS PF05401.6 OAJ28893.1 - 0.00046 19.6 0.0 0.01 15.2 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) RrnaAD PF00398.15 OAJ28893.1 - 0.00049 19.2 0.0 0.0012 17.9 0.0 1.6 1 1 1 2 2 2 1 Ribosomal RNA adenine dimethylase Zip PF02535.17 OAJ28893.1 - 0.0028 16.7 17.7 0.0038 16.2 12.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DREV PF05219.7 OAJ28893.1 - 0.0045 15.8 0.0 0.013 14.3 0.0 1.6 2 0 0 2 2 2 1 DREV methyltransferase TehB PF03848.9 OAJ28893.1 - 0.005 16.0 0.0 0.11 11.6 0.0 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TehB PCMT PF01135.14 OAJ28893.1 - 0.01 15.3 0.0 0.16 11.5 0.0 2.1 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 OAJ28893.1 - 0.031 12.9 0.0 0.58 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) TPMT PF05724.6 OAJ28893.1 - 0.061 12.7 0.0 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) AlaDh_PNT_C PF01262.16 OAJ28893.1 - 0.072 12.6 0.1 0.16 11.5 0.0 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pox_MCEL PF03291.11 OAJ28893.1 - 0.094 11.5 0.0 0.17 10.7 0.0 1.4 1 1 0 1 1 1 0 mRNA capping enzyme Gryzun PF07919.7 OAJ28894.1 - 2.9e-29 101.8 0.0 7e-28 97.2 0.0 2.6 2 1 0 2 2 2 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 OAJ28894.1 - 0.001 18.6 0.0 0.0027 17.2 0.0 1.7 1 1 0 1 1 1 1 Foie gras liver health family 1 PPTA PF01239.17 OAJ28896.1 - 4e-43 143.0 18.0 5.5e-09 34.9 0.1 5.8 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat GalKase_gal_bdg PF10509.4 OAJ28897.1 - 5.5e-21 73.5 0.0 9.2e-21 72.8 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 OAJ28897.1 - 4.4e-13 49.0 3.4 1.3e-12 47.6 0.8 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain Aconitase PF00330.15 OAJ28898.1 - 3.6e-150 500.4 0.0 7.2e-150 499.5 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAJ28898.1 - 6.5e-32 110.3 0.0 1.4e-31 109.2 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain MRP-L28 PF09812.4 OAJ28898.1 - 0.00079 19.2 0.3 0.0036 17.1 0.2 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L28 CoA_transf_3 PF02515.12 OAJ28899.1 - 4.2e-46 156.6 0.0 6.5e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III DUF544 PF04424.8 OAJ28904.1 - 5.4e-15 55.2 0.0 1.1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF1764 PF08576.5 OAJ28907.1 - 5.9e-18 65.5 22.9 8.9e-18 64.9 4.0 2.6 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) DUF3484 PF11983.3 OAJ28907.1 - 0.55 11.0 13.3 0.073 13.9 5.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3484) DUF966 PF06136.8 OAJ28907.1 - 0.95 8.8 14.2 1.2 8.4 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Consortin_C PF15281.1 OAJ28907.1 - 1.7 8.1 5.7 1.4 8.4 2.3 2.0 1 1 2 3 3 3 0 Consortin C-terminus DUF1510 PF07423.6 OAJ28907.1 - 4.2 6.6 17.5 5.3 6.3 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CMV_1a PF12467.3 OAJ28907.1 - 6.7 7.0 13.6 8.7 6.6 9.4 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Macoilin PF09726.4 OAJ28907.1 - 9.1 4.4 12.4 11 4.1 8.6 1.1 1 0 0 1 1 1 0 Transmembrane protein HA2 PF04408.18 OAJ28908.1 - 2e-14 53.4 0.2 7.8e-14 51.5 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ28908.1 - 9.3e-12 44.6 0.1 2.6e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 OAJ28908.1 - 1.7e-07 31.7 5.5 0.00029 21.3 0.2 3.0 3 0 0 3 3 3 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.11 OAJ28908.1 - 1.5e-06 28.0 0.0 3.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 OAJ28908.1 - 8.1e-06 25.4 0.0 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Cytochrom_C PF00034.16 OAJ28909.1 - 8.6e-10 39.3 0.1 1.5e-09 38.5 0.1 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 OAJ28909.1 - 1e-07 31.9 2.2 1.4e-06 28.3 1.6 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 OAJ28909.1 - 0.0011 18.4 0.1 0.0088 15.4 0.0 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain Haem_bd PF14376.1 OAJ28909.1 - 0.062 12.9 0.2 0.93 9.1 0.0 2.1 2 0 0 2 2 2 0 Haem-binding domain EOS1 PF12326.3 OAJ28910.1 - 1.9e-17 63.3 0.0 3.7e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 N-glycosylation protein Serglycin PF04360.7 OAJ28910.1 - 0.0031 17.2 4.6 0.0031 17.2 3.2 6.2 5 1 1 6 6 6 1 Serglycin ARL6IP6 PF15062.1 OAJ28910.1 - 1.4 8.8 7.6 1.5 8.8 0.5 2.9 1 1 0 2 2 2 0 Haemopoietic lineage transmembrane helix EMP24_GP25L PF01105.19 OAJ28911.1 - 1.7e-28 99.6 6.0 3.5e-15 56.1 1.7 2.0 1 1 1 2 2 2 2 emp24/gp25L/p24 family/GOLD DUF3500 PF12006.3 OAJ28911.1 - 0.058 12.3 0.0 0.28 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3500) eRF1_2 PF03464.10 OAJ28912.1 - 3.9e-43 146.9 0.0 6.3e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 OAJ28912.1 - 3e-37 127.3 0.1 5.8e-37 126.4 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 OAJ28912.1 - 1.8e-25 89.0 0.0 3.1e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 TIP120 PF08623.5 OAJ28913.1 - 4.5e-51 172.7 5.2 4.6e-50 169.4 0.1 3.6 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 OAJ28913.1 - 8.6e-24 83.6 26.0 0.0044 17.2 0.0 9.7 6 3 2 8 8 8 7 HEAT repeats HEAT PF02985.17 OAJ28913.1 - 8.4e-11 41.0 27.6 0.65 10.2 0.1 12.3 14 1 1 15 15 12 3 HEAT repeat HEAT_EZ PF13513.1 OAJ28913.1 - 5.9e-08 32.9 45.3 0.55 10.7 0.0 13.8 12 3 3 15 15 15 4 HEAT-like repeat Adaptin_N PF01602.15 OAJ28913.1 - 7.4e-07 27.8 21.2 0.00038 18.9 0.2 6.5 2 2 3 5 5 5 3 Adaptin N terminal region UME PF08064.8 OAJ28913.1 - 2.4e-06 27.4 1.3 4.8 7.1 0.0 5.9 6 1 1 7 7 6 2 UME (NUC010) domain Vac14_Fab1_bd PF12755.2 OAJ28913.1 - 0.0004 20.7 0.8 3.6 8.0 0.1 6.9 8 1 1 9 9 8 1 Vacuolar 14 Fab1-binding region Pex16 PF08610.5 OAJ28913.1 - 0.0027 16.7 0.0 0.078 11.9 0.0 2.4 2 0 0 2 2 2 1 Peroxisomal membrane protein (Pex16) SporV_AA PF12164.3 OAJ28913.1 - 0.057 13.4 0.1 13 5.8 0.0 2.8 2 0 0 2 2 2 0 Stage V sporulation protein AA RRN3 PF05327.6 OAJ28913.1 - 0.071 11.2 5.0 0.076 11.1 1.1 2.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Upf2 PF04050.9 OAJ28913.1 - 0.089 12.5 7.1 0.18 11.5 5.0 1.4 1 0 0 1 1 1 0 Up-frameshift suppressor 2 DUF3385 PF11865.3 OAJ28913.1 - 0.11 12.4 5.8 4 7.3 0.0 4.9 5 1 1 6 6 6 0 Domain of unknown function (DUF3385) CDC45 PF02724.9 OAJ28913.1 - 1.4 6.8 7.6 0.88 7.5 2.8 2.0 2 0 0 2 2 2 0 CDC45-like protein DUF3752 PF12572.3 OAJ28914.1 - 5.3e-11 42.8 15.3 5.3e-11 42.8 10.6 4.1 2 1 2 4 4 4 2 Protein of unknown function (DUF3752) TFIIE-A_C-term PF11521.3 OAJ28915.1 - 0.48 10.3 3.4 0.3 11.0 0.7 1.8 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Formyl_trans_N PF00551.14 OAJ28916.1 - 3.2e-30 104.9 0.0 4.4e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 OAJ28916.1 - 3.6e-08 32.7 0.0 9e-08 31.4 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 OAJ28916.1 - 0.0001 21.9 0.2 0.00028 20.5 0.0 1.8 2 0 0 2 2 2 1 ACT domain DUF3722 PF12519.3 OAJ28917.1 - 6.3e-82 274.6 4.1 3.4e-80 269.0 0.2 3.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 OAJ28917.1 - 0.00012 21.4 0.1 0.0006 19.2 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic porin DUF605 PF04652.11 OAJ28917.1 - 2.1 7.6 34.3 0.074 12.4 8.8 2.2 2 0 0 2 2 2 0 Vta1 like PAT1 PF09770.4 OAJ28917.1 - 2.8 6.0 14.0 6.2 4.9 0.2 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Septin PF00735.13 OAJ28918.1 - 1.5e-107 358.7 0.0 1.5e-107 358.7 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 OAJ28918.1 - 3.4e-07 30.2 0.0 7.2e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 OAJ28918.1 - 0.00024 20.9 5.4 0.046 13.5 0.1 3.1 2 1 1 3 3 3 2 Dynamin family AAA_17 PF13207.1 OAJ28918.1 - 0.00039 21.2 3.9 0.0052 17.5 2.7 2.6 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 OAJ28918.1 - 0.00041 19.8 0.1 0.0099 15.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 OAJ28918.1 - 0.00054 20.1 0.0 0.0028 17.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 OAJ28918.1 - 0.0006 19.0 0.4 0.003 16.7 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 OAJ28918.1 - 0.0012 18.8 1.4 0.047 13.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 OAJ28918.1 - 0.0013 19.2 0.0 0.0038 17.7 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 OAJ28918.1 - 0.0014 18.1 0.4 0.0032 16.9 0.1 1.6 2 0 0 2 2 1 1 FtsK/SpoIIIE family AIG1 PF04548.11 OAJ28918.1 - 0.0022 17.1 0.1 0.0044 16.1 0.0 1.6 1 1 0 1 1 1 1 AIG1 family AAA_33 PF13671.1 OAJ28918.1 - 0.0031 17.3 0.4 0.0086 15.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 OAJ28918.1 - 0.0047 16.6 0.0 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.8 OAJ28918.1 - 0.0057 15.5 0.1 0.014 14.2 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 OAJ28918.1 - 0.011 15.9 0.4 0.035 14.4 0.0 2.0 2 1 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.12 OAJ28918.1 - 0.026 14.0 0.4 1 8.8 0.2 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IncA PF04156.9 OAJ28918.1 - 0.045 13.3 4.3 0.075 12.6 3.0 1.3 1 0 0 1 1 1 0 IncA protein cobW PF02492.14 OAJ28918.1 - 0.055 12.9 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AbiH PF14253.1 OAJ28918.1 - 0.063 12.8 1.1 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH AAA_19 PF13245.1 OAJ28918.1 - 0.07 12.8 0.2 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 OAJ28918.1 - 0.084 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 OAJ28918.1 - 0.088 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 OAJ28918.1 - 0.093 12.1 0.3 0.27 10.6 0.1 1.7 1 1 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.4 OAJ28918.1 - 0.1 12.0 0.3 0.32 10.4 0.0 1.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 OAJ28918.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.1 OAJ28918.1 - 0.12 12.6 5.5 0.081 13.2 0.7 2.9 1 1 2 3 3 3 0 AAA domain Ras PF00071.17 OAJ28918.1 - 0.15 11.4 0.7 0.48 9.8 0.0 2.2 3 0 0 3 3 3 0 Ras family OmpH PF03938.9 OAJ28918.1 - 0.17 11.7 4.5 0.35 10.8 3.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF87 PF01935.12 OAJ28918.1 - 0.46 10.2 5.2 0.61 9.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Atg14 PF10186.4 OAJ28918.1 - 0.67 8.8 6.3 0.97 8.3 4.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Histone PF00125.19 OAJ28919.1 - 6.3e-19 67.8 0.1 1e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAT1 PF09770.4 OAJ28920.1 - 0.38 8.9 7.3 0.44 8.7 5.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Oxidored_FMN PF00724.15 OAJ28922.1 - 8e-50 169.7 0.0 2e-39 135.5 0.0 3.1 3 0 0 3 3 3 3 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 OAJ28922.1 - 0.014 14.6 0.0 4.8 6.4 0.0 2.4 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel MutL PF13941.1 OAJ28922.1 - 0.084 11.1 0.1 0.13 10.5 0.1 1.2 1 0 0 1 1 1 0 MutL protein CTDII PF01556.13 OAJ28923.1 - 6.5e-27 93.2 0.4 4.6e-18 64.8 0.0 3.4 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 OAJ28923.1 - 3.4e-22 77.9 4.4 5.5e-22 77.2 3.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 OAJ28923.1 - 1.8e-09 37.4 16.8 3.9e-09 36.4 11.1 2.0 2 0 0 2 2 2 1 DnaJ central domain UQ_con PF00179.21 OAJ28924.1 - 8.7e-53 177.5 0.0 9.8e-53 177.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ28924.1 - 0.00012 21.8 0.0 0.00014 21.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 OAJ28924.1 - 0.013 15.4 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 OAJ28924.1 - 0.044 13.4 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Peptidase_C48 PF02902.14 OAJ28925.1 - 1.3e-25 90.2 0.0 3.8e-25 88.7 0.0 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SUR7 PF06687.7 OAJ28926.1 - 1.1e-25 90.5 2.7 1.3e-25 90.2 1.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2207 PF09972.4 OAJ28926.1 - 0.026 13.1 0.0 0.03 12.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Lig_chan PF00060.21 OAJ28926.1 - 0.059 13.0 0.4 0.12 12.0 0.1 1.6 1 1 0 1 1 1 0 Ligand-gated ion channel Amastin PF07344.6 OAJ28926.1 - 1.9 8.0 7.3 0.49 10.0 2.8 1.7 2 0 0 2 2 2 0 Amastin surface glycoprotein HAD PF12710.2 OAJ28928.1 - 6.6e-17 62.3 0.0 2.4e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 OAJ28928.1 - 1.6e-16 60.0 0.1 1.1e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 OAJ28928.1 - 2.3e-13 51.0 5.1 3.2e-09 37.5 3.3 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ28928.1 - 8.4e-13 48.0 0.0 2.2e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAJ28928.1 - 0.0022 17.5 0.1 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PAP2 PF01569.16 OAJ28929.1 - 4.1e-10 39.4 7.0 1.5e-09 37.5 4.9 1.9 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 OAJ28929.1 - 8.3e-05 22.1 8.4 0.00042 19.8 5.8 2.1 1 1 0 1 1 1 1 PAP2 superfamily Serglycin PF04360.7 OAJ28929.1 - 0.011 15.4 5.3 0.011 15.4 3.7 4.5 2 1 1 3 3 3 0 Serglycin PAP2_C PF14360.1 OAJ28929.1 - 2.1 8.6 8.3 0.42 10.9 2.5 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Ribosomal_L37ae PF01780.14 OAJ28930.1 - 2.7e-39 132.9 7.0 3e-39 132.7 4.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 OAJ28930.1 - 0.0015 18.3 2.3 0.0023 17.6 1.6 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 OAJ28930.1 - 0.0075 16.0 4.8 1.1 9.0 3.3 2.4 1 1 0 1 1 1 1 BED zinc finger Zn-ribbon_8 PF09723.5 OAJ28930.1 - 0.033 14.1 1.8 0.27 11.2 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain A2L_zn_ribbon PF08792.5 OAJ28930.1 - 0.05 13.0 4.5 0.22 11.0 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-FCS PF06467.9 OAJ28930.1 - 0.08 12.6 2.5 0.14 11.8 0.2 2.0 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.1 OAJ28930.1 - 0.14 12.4 7.4 0.31 11.4 0.7 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Elf1 PF05129.8 OAJ28930.1 - 0.16 11.6 3.5 0.28 10.9 2.5 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like C1_1 PF00130.17 OAJ28930.1 - 0.19 11.5 2.5 0.27 10.9 1.7 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Tnp_zf-ribbon_2 PF13842.1 OAJ28930.1 - 0.24 11.8 3.1 0.46 10.9 2.1 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon OrfB_Zn_ribbon PF07282.6 OAJ28930.1 - 0.25 11.0 4.5 0.29 10.8 2.4 1.6 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Sgf11 PF08209.6 OAJ28930.1 - 0.41 9.9 2.2 1.1 8.5 0.0 2.4 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Ribosomal_L44 PF00935.14 OAJ28930.1 - 2.3 8.2 7.5 7.4 6.6 1.5 2.2 1 1 1 2 2 2 0 Ribosomal protein L44 Sec8_exocyst PF04048.9 OAJ28931.1 - 1.6e-33 115.3 0.2 4.2e-33 113.9 0.1 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 OAJ28931.1 - 1.2e-05 24.4 0.4 2.6e-05 23.2 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 OAJ28931.1 - 1.4e-05 24.9 0.6 0.00014 21.7 0.1 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2451 PF10474.4 OAJ28931.1 - 0.03 14.0 0.0 0.099 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) COG6 PF06419.6 OAJ28932.1 - 0.21 9.6 0.2 0.28 9.2 0.1 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Fe-ADH PF00465.14 OAJ28933.1 - 6.3e-68 229.0 0.0 8.2e-68 228.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 OAJ28933.1 - 6.5e-16 58.3 0.4 1.4e-14 54.0 0.3 2.3 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 OAJ28933.1 - 0.0051 15.7 0.2 0.31 9.9 0.0 2.4 3 0 0 3 3 3 2 3-dehydroquinate synthase DUF1676 PF07898.8 OAJ28934.1 - 0.016 15.4 0.8 0.059 13.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Methyltransf_11 PF08241.7 OAJ28935.1 - 4.5e-06 27.0 0.2 5.6e-05 23.5 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ28935.1 - 0.00034 20.2 0.0 0.0015 18.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ28935.1 - 0.00098 19.4 0.0 0.017 15.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ28935.1 - 0.0084 15.8 0.0 0.033 13.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ28935.1 - 0.0089 16.6 0.3 0.032 14.8 0.2 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ28935.1 - 0.011 16.2 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ28935.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF3663 PF12404.3 OAJ28935.1 - 0.32 10.7 2.2 0.64 9.8 0.4 2.0 2 0 0 2 2 2 0 Peptidase DUF4131 PF13567.1 OAJ28936.1 - 0.054 12.9 1.1 0.16 11.3 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) UPF0182 PF03699.8 OAJ28936.1 - 8.5 4.1 12.1 0.5 8.2 3.3 2.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0182) CNH PF00780.17 OAJ28939.1 - 2.2e-83 279.8 0.0 3.8e-83 279.0 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 OAJ28939.1 - 1.9e-45 154.1 0.0 4e-45 153.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 OAJ28939.1 - 1.4e-39 135.8 0.6 2.5e-39 135.0 0.4 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 OAJ28939.1 - 1.4e-11 43.9 0.0 2.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_10 PF15411.1 OAJ28939.1 - 0.042 14.0 0.1 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain BolA PF01722.13 OAJ28940.1 - 8.4e-28 96.1 0.5 1.1e-27 95.7 0.3 1.1 1 0 0 1 1 1 1 BolA-like protein HATPase_c PF02518.21 OAJ28941.1 - 3.8e-17 62.0 0.2 1e-16 60.6 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAJ28941.1 - 6.6e-17 61.5 0.0 4.7e-10 39.4 0.0 3.5 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.20 OAJ28941.1 - 3.2e-16 59.0 0.0 1.1e-15 57.3 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 OAJ28941.1 - 0.0011 19.1 0.1 0.038 14.0 0.0 2.8 2 0 0 2 2 2 1 GAF domain p450 PF00067.17 OAJ28942.1 - 3.3e-54 184.1 0.0 4e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF987 PF06174.6 OAJ28943.1 - 0.14 11.7 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF987) Tim17 PF02466.14 OAJ28944.1 - 5.2e-27 94.4 6.1 6.4e-27 94.1 4.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.20 OAJ28947.1 - 4.9e-58 196.3 0.0 4.8e-57 193.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28947.1 - 1.2e-33 116.3 0.0 1.9e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ28947.1 - 5.5e-05 23.0 0.0 5.5e-05 23.0 0.0 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ28947.1 - 0.0016 17.4 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF3584 PF12128.3 OAJ28947.1 - 0.01 13.2 11.5 0.017 12.5 8.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PNP_UDP_1 PF01048.15 OAJ28948.1 - 3.6e-34 117.7 0.7 4.2e-34 117.5 0.5 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Zn_clus PF00172.13 OAJ28949.1 - 0.00016 21.4 11.6 0.00016 21.4 8.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.1 OAJ28949.1 - 0.00022 21.5 0.0 0.00078 19.7 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 OAJ28949.1 - 0.00028 20.6 0.0 0.00069 19.3 0.0 1.7 2 0 0 2 2 2 1 PAS fold LysM PF01476.15 OAJ28950.1 - 0.00016 21.5 0.0 0.00037 20.3 0.0 1.7 1 0 0 1 1 1 1 LysM domain DTHCT PF08070.6 OAJ28950.1 - 0.11 13.1 3.4 0.43 11.2 2.4 2.0 1 0 0 1 1 1 0 DTHCT (NUC029) region WD40 PF00400.27 OAJ28951.1 - 1e-27 94.9 10.3 2.1e-07 30.5 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat SNF2_N PF00176.18 OAJ28952.1 - 3.4e-69 232.9 0.5 5e-69 232.3 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 OAJ28952.1 - 4.2e-16 59.0 0.6 4.2e-16 59.0 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 OAJ28952.1 - 4.8e-14 51.9 0.0 1.3e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 OAJ28952.1 - 4.5e-13 48.6 1.0 2.5e-08 33.4 0.2 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain TRAPP PF04051.11 OAJ28953.1 - 2.2e-31 108.4 0.0 2.6e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component TFIIIC_delta PF12657.2 OAJ28954.1 - 1.5e-08 34.5 0.2 3.8e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 OAJ28954.1 - 0.0028 17.5 0.7 0.0062 16.4 0.5 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TPT PF03151.11 OAJ28955.1 - 6.7e-31 107.0 4.2 6.7e-31 107.0 2.9 2.8 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 OAJ28955.1 - 1.3e-12 47.8 21.9 5.9e-07 29.5 3.3 2.6 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 OAJ28955.1 - 1e-09 37.7 12.5 2.2e-09 36.7 8.7 1.5 1 1 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.14 OAJ28955.1 - 1.1 9.7 10.1 0.19 12.2 3.5 2.3 2 0 0 2 2 2 0 Small Multidrug Resistance protein Chitin_synth_1 PF01644.12 OAJ28956.1 - 8.7e-86 285.7 0.1 1.9e-85 284.6 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 OAJ28956.1 - 5e-28 96.6 0.0 1.1e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 OAJ28956.1 - 2.3e-22 79.1 3.8 3.9e-17 61.8 0.0 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 OAJ28956.1 - 1.2e-06 28.3 6.4 5.7e-06 26.1 4.4 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ28956.1 - 2.4e-06 27.5 0.0 5.3e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 TFIIA PF03153.8 OAJ28956.1 - 1.5 8.6 9.0 2.3 8.0 6.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4451 PF14616.1 OAJ28957.1 - 0.19 11.4 0.0 0.49 10.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Dicty_REP PF05086.7 OAJ28958.1 - 0.85 7.3 9.1 1.8 6.2 6.3 1.5 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.20 OAJ28959.1 - 6.1e-61 205.8 0.0 8.4e-61 205.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28959.1 - 4.9e-39 133.9 0.0 6.5e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ28959.1 - 1.2e-05 24.3 0.0 2.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Sororin PF09666.5 OAJ28959.1 - 0.0041 17.3 1.3 0.0072 16.5 0.5 1.6 1 1 0 1 1 1 1 Sororin protein F-box PF00646.28 OAJ28960.1 - 8.4e-08 31.6 0.0 1.7e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 OAJ28960.1 - 0.056 13.1 0.2 0.55 9.9 0.2 2.1 1 1 0 1 1 1 0 F-box-like domain DUF572 PF04502.8 OAJ28962.1 - 0.31 10.2 11.6 0.51 9.4 8.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Sigma70_ner PF04546.8 OAJ28962.1 - 0.44 10.1 14.8 0.38 10.3 6.7 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region COPI_C PF06957.6 OAJ28962.1 - 0.66 8.4 4.2 0.96 7.9 2.9 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Macoilin PF09726.4 OAJ28962.1 - 0.96 7.6 10.7 1.2 7.3 7.4 1.1 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 OAJ28962.1 - 1.1 8.7 30.0 0.84 9.0 19.5 1.6 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein YL1 PF05764.8 OAJ28962.1 - 8.1 5.9 30.7 0.027 14.0 14.5 1.7 2 1 0 2 2 2 0 YL1 nuclear protein Nucleoplasmin PF03066.10 OAJ28962.1 - 8.6 5.8 18.2 5.6 6.4 8.5 2.5 2 0 0 2 2 2 0 Nucleoplasmin MOSC_N PF03476.11 OAJ28963.1 - 2.5e-17 62.7 0.0 4.7e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 OAJ28963.1 - 5e-08 32.4 0.0 0.2 11.0 0.0 3.4 3 1 0 3 3 3 3 MOSC domain LELP1 PF15042.1 OAJ28964.1 - 0.042 14.0 3.9 0.053 13.7 2.7 1.1 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Vanabin-2 PF11437.3 OAJ28964.1 - 0.06 13.3 6.0 0.078 12.9 4.2 1.2 1 0 0 1 1 1 0 Vanadium-binding protein 2 zf-met PF12874.2 OAJ28964.1 - 0.48 10.6 0.1 0.48 10.6 0.1 2.7 2 1 1 3 3 3 0 Zinc-finger of C2H2 type zf-RING_2 PF13639.1 OAJ28965.1 - 1.6e-09 37.4 4.8 1.6e-09 37.4 3.3 2.7 2 1 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 OAJ28965.1 - 6.5e-09 35.7 0.7 6.5e-09 35.7 0.5 1.7 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_3 PF14369.1 OAJ28965.1 - 1.5e-06 28.0 1.1 1.5e-06 28.0 0.8 3.0 3 0 0 3 3 3 1 zinc-finger zf-C3HC4_3 PF13920.1 OAJ28965.1 - 2.3e-06 27.1 9.8 5e-06 26.0 2.2 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ28965.1 - 6.3e-06 26.1 0.6 6.3e-06 26.1 0.4 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ28965.1 - 3.7e-05 23.3 0.6 3.7e-05 23.3 0.4 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 OAJ28965.1 - 0.00058 19.6 2.3 0.0018 18.0 1.6 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 OAJ28965.1 - 0.00072 19.1 2.2 0.00072 19.1 1.5 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 OAJ28965.1 - 0.017 14.9 1.6 0.043 13.6 1.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.2 OAJ28965.1 - 0.04 13.7 3.8 1.4 8.8 0.1 3.1 3 0 0 3 3 3 0 Double zinc ribbon FANCL_C PF11793.3 OAJ28965.1 - 0.073 13.0 4.2 1.2 9.1 2.9 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain Zn-ribbon_8 PF09723.5 OAJ28965.1 - 0.16 11.9 6.0 0.29 11.0 0.4 3.0 3 0 0 3 3 3 0 Zinc ribbon domain HypA PF01155.14 OAJ28965.1 - 0.85 9.3 3.2 0.79 9.4 0.1 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Prok-RING_4 PF14447.1 OAJ28965.1 - 2 8.0 6.4 0.089 12.3 0.4 1.8 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 2-oxoacid_dh PF00198.18 OAJ28967.1 - 5e-79 264.8 0.0 7.4e-79 264.2 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 OAJ28967.1 - 2e-19 69.0 1.9 3.6e-19 68.1 1.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.1 OAJ28967.1 - 0.0011 19.2 0.1 0.73 10.2 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 OAJ28967.1 - 0.0026 17.4 0.0 0.24 11.1 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 OAJ28967.1 - 0.0046 16.1 16.4 0.065 12.3 6.2 2.4 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.14 OAJ28967.1 - 0.013 15.1 0.3 0.028 14.0 0.2 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF605 PF04652.11 OAJ28967.1 - 0.84 8.9 18.8 1.1 8.5 13.0 1.1 1 0 0 1 1 1 0 Vta1 like NUDIX PF00293.23 OAJ28968.1 - 2.2e-16 59.6 0.1 7.1e-16 58.0 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain DUF1770 PF08589.5 OAJ28969.1 - 0.00018 22.0 1.5 0.00033 21.1 0.2 1.9 1 1 1 2 2 2 1 Fungal protein of unknown function (DUF1770) Thiolase_N PF00108.18 OAJ28971.1 - 5.7e-83 277.9 2.1 7.6e-83 277.5 1.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAJ28971.1 - 3.2e-49 165.4 0.5 8.7e-49 164.0 0.3 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 OAJ28971.1 - 3.6e-05 23.3 1.6 9.2e-05 22.0 1.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Yippee-Mis18 PF03226.9 OAJ28973.1 - 3.7e-20 71.7 0.5 4.1e-20 71.6 0.4 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 OAJ28973.1 - 0.13 12.1 1.3 0.27 11.1 0.9 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I Evr1_Alr PF04777.8 OAJ28973.1 - 0.15 11.9 0.5 0.44 10.4 0.0 1.9 1 1 1 2 2 2 0 Erv1 / Alr family Endonuclease_7 PF02945.10 OAJ28973.1 - 0.16 11.6 2.4 0.51 10.0 1.7 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII UPF0047 PF01894.12 OAJ28974.1 - 6.1e-41 138.9 0.0 8.6e-41 138.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Mito_carr PF00153.22 OAJ28975.1 - 1.7e-46 155.8 0.9 9.4e-16 57.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PQ-loop PF04193.9 OAJ28976.1 - 1.4e-29 101.3 1.0 5.8e-17 60.9 0.3 2.6 2 0 0 2 2 2 2 PQ loop repeat Alb1 PF09135.6 OAJ28977.1 - 0.054 14.1 8.2 0.11 13.1 5.7 1.5 1 0 0 1 1 1 0 Alb1 DDE_Tnp_4 PF13359.1 OAJ28978.1 - 7.6e-23 80.8 0.0 1.4e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Nucleoplasmin PF03066.10 OAJ28979.1 - 0.44 10.0 10.0 0.85 9.1 6.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin Nucleo_P87 PF07267.6 OAJ28979.1 - 1.5 7.4 7.4 2.5 6.6 5.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.7 OAJ28979.1 - 9.7 5.3 9.2 16 4.6 6.4 1.3 1 0 0 1 1 1 0 NOA36 protein SH3_1 PF00018.23 OAJ28980.1 - 7.2e-14 50.9 0.2 1.4e-13 49.9 0.2 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 OAJ28980.1 - 2.2e-12 47.0 0.0 5e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.1 OAJ28980.1 - 1.1e-11 44.0 0.1 2.2e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 OAJ28980.1 - 1.2e-08 34.6 0.0 1.9e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 OAJ28980.1 - 2e-08 33.5 0.0 4.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 OAJ28980.1 - 6.8e-06 26.1 0.1 1.5e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 OAJ28980.1 - 0.00041 20.3 0.2 0.00076 19.4 0.2 1.4 1 0 0 1 1 1 1 Ste50p, sterile alpha motif PH_11 PF15413.1 OAJ28980.1 - 0.19 12.0 0.2 0.52 10.5 0.1 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain WD40 PF00400.27 OAJ28981.1 - 2.6e-54 179.2 17.8 2.6e-10 39.7 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 OAJ28981.1 - 0.00017 19.9 0.0 0.0015 16.8 0.0 2.0 2 0 0 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.3 OAJ28981.1 - 0.0022 16.2 1.0 2.8 5.9 0.0 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 OAJ28981.1 - 0.041 13.6 0.0 0.42 10.4 0.0 2.6 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region SH3_6 PF12913.2 OAJ28981.1 - 0.095 11.9 0.0 0.72 9.1 0.0 2.3 2 0 0 2 2 2 0 SH3 domain of the SH3b1 type PD40 PF07676.7 OAJ28981.1 - 0.15 11.7 1.7 26 4.6 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 OAJ28981.1 - 0.93 9.8 8.0 1.2 9.5 0.5 4.0 3 1 0 3 3 3 0 PQQ-like domain Pkinase PF00069.20 OAJ28982.1 - 7.2e-20 71.2 0.0 1.2e-11 44.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ28982.1 - 6.9e-10 38.4 0.3 6.5e-08 31.9 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Gtr1_RagA PF04670.7 OAJ28983.1 - 1.5e-82 276.2 0.0 2.1e-82 275.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 OAJ28983.1 - 0.00017 20.9 0.0 0.00036 19.9 0.0 1.6 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 OAJ28983.1 - 0.00026 20.9 0.0 0.00054 19.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 OAJ28983.1 - 0.00033 19.9 0.0 0.00051 19.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 OAJ28983.1 - 0.0018 18.7 0.0 0.0041 17.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 OAJ28983.1 - 0.0056 16.1 0.7 0.025 14.0 0.1 2.3 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 OAJ28983.1 - 0.033 13.1 0.0 0.069 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 OAJ28983.1 - 0.093 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter WD40 PF00400.27 OAJ28984.1 - 2.8e-12 46.0 1.1 0.00037 20.2 0.2 3.3 2 1 0 2 2 2 2 WD domain, G-beta repeat PQQ_3 PF13570.1 OAJ28984.1 - 0.05 13.8 0.3 0.38 11.0 0.3 2.1 2 0 0 2 2 2 0 PQQ-like domain CRT10 PF08728.5 OAJ28984.1 - 0.16 9.9 0.0 0.21 9.5 0.0 1.1 1 0 0 1 1 1 0 CRT10 TPR_12 PF13424.1 OAJ28985.1 - 0.00063 19.6 10.6 0.18 11.7 4.2 4.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ28985.1 - 0.0017 18.1 4.3 0.61 10.0 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF3856 PF12968.2 OAJ28985.1 - 0.018 14.8 1.8 4.9 6.9 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) HTH_Mga PF08280.6 OAJ28985.1 - 0.081 12.7 0.6 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain TPR_14 PF13428.1 OAJ28985.1 - 2.4 9.0 5.8 29 5.6 0.4 4.8 5 1 0 6 6 6 0 Tetratricopeptide repeat tRNA_U5-meth_tr PF05958.6 OAJ28986.1 - 2.6e-18 65.8 0.0 6.4e-17 61.2 0.0 2.4 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_26 PF13659.1 OAJ28986.1 - 6.7e-07 29.3 0.0 1.2e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ28986.1 - 3.3e-06 26.7 0.0 5.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 OAJ28986.1 - 3.5e-05 23.4 0.0 6.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TRAM PF01938.15 OAJ28986.1 - 8.2e-05 22.3 1.4 0.00018 21.2 0.9 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_18 PF12847.2 OAJ28986.1 - 0.00071 20.1 0.0 0.002 18.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ28986.1 - 0.0039 16.5 0.0 0.009 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.6 OAJ28986.1 - 0.0052 16.2 0.0 0.0095 15.3 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Met_10 PF02475.11 OAJ28986.1 - 0.0062 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein MEF2_binding PF09047.5 OAJ28986.1 - 0.017 14.7 0.1 2.6 7.7 0.0 2.9 2 0 0 2 2 2 0 MEF2 binding PrmA PF06325.8 OAJ28986.1 - 0.02 14.0 0.0 0.044 12.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aminotran_4 PF01063.14 OAJ28987.1 - 3.5e-21 75.7 0.0 5.8e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV SKN1 PF03935.10 OAJ28989.1 - 3.5e-181 602.7 0.5 4.5e-181 602.4 0.3 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 OAJ28989.1 - 4.9e-07 29.2 0.1 0.00024 20.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 EF-hand_5 PF13202.1 OAJ28989.1 - 0.065 12.5 0.0 0.22 10.9 0.0 1.9 1 0 0 1 1 1 0 EF hand DUF2673 PF10880.3 OAJ28990.1 - 0.034 14.1 0.1 0.042 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) zf-ribbon_3 PF13248.1 OAJ28993.1 - 0.27 10.5 9.0 0.08 12.1 3.6 1.9 1 1 0 1 1 1 0 zinc-ribbon domain SWIRM PF04433.12 OAJ28994.1 - 1.2e-33 115.1 0.0 2.2e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 OAJ28994.1 - 2.8e-08 33.1 0.8 4.8e-08 32.4 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 OAJ28994.1 - 7.3e-07 29.2 0.0 2.1e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 OAJ28994.1 - 7.9e-05 22.6 0.1 0.00017 21.5 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2450 PF10475.4 OAJ28994.1 - 0.23 10.3 0.5 0.44 9.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) ODC_AZ PF02100.12 OAJ28996.1 - 5e-15 54.9 0.0 1.2e-14 53.7 0.0 1.5 1 1 0 1 1 1 1 Ornithine decarboxylase antizyme Med21 PF11221.3 OAJ28999.1 - 0.19 11.6 1.4 0.21 11.5 0.2 1.7 2 0 0 2 2 2 0 Subunit 21 of Mediator complex LAGLIDADG_3 PF14528.1 OAJ29001.1 - 1.5e-05 25.1 0.0 0.00036 20.7 0.0 2.5 2 0 0 2 2 2 1 LAGLIDADG-like domain Hom_end PF05204.9 OAJ29001.1 - 0.007 16.3 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 1 Homing endonuclease KASH PF10541.4 OAJ29002.1 - 2.3 8.1 6.0 4.8 7.1 4.2 1.5 1 1 0 1 1 1 0 Nuclear envelope localisation domain PCI PF01399.22 OAJ29004.1 - 2.6e-05 24.4 0.0 5.5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain LRR_6 PF13516.1 OAJ29008.1 - 0.077 13.1 4.6 63 4.1 0.0 5.5 5 0 0 5 5 5 0 Leucine Rich repeat Hydantoinase_B PF02538.9 OAJ29009.1 - 1e-183 611.3 0.0 3.8e-182 606.1 0.0 2.0 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase PPR_3 PF13812.1 OAJ29012.1 - 0.0018 18.4 0.6 0.39 11.1 0.0 4.6 4 0 0 4 4 4 1 Pentatricopeptide repeat domain DIL PF01843.14 OAJ29013.1 - 1.9e-19 69.4 0.2 4.1e-19 68.4 0.1 1.6 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.2 OAJ29013.1 - 5.7e-16 58.6 0.0 3e-15 56.3 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ29013.1 - 2.9e-12 45.7 0.3 9.2e-07 28.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 OAJ29013.1 - 4.2e-11 41.9 0.1 0.00012 21.9 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 OAJ29013.1 - 9.4e-11 41.9 0.0 2.7e-09 37.2 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ29013.1 - 9.7e-11 41.5 0.3 1.1e-07 31.8 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Yae1_N PF09811.4 OAJ29014.1 - 2e-07 30.3 4.8 4.6e-07 29.2 3.3 1.7 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RRM_1 PF00076.17 OAJ29014.1 - 0.00048 19.7 0.1 0.072 12.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zip PF02535.17 OAJ29014.1 - 0.79 8.6 6.0 1.6 7.6 4.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 OAJ29014.1 - 1.5 8.6 6.2 3.5 7.4 4.3 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region adh_short PF00106.20 OAJ29015.1 - 1.6e-25 89.9 1.0 2.9e-25 89.1 0.7 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ29015.1 - 5.1e-10 39.3 2.6 8.3e-10 38.6 0.3 2.3 2 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 OAJ29015.1 - 6.7e-08 32.5 0.0 9.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HHH_5 PF14520.1 OAJ29015.1 - 0.027 14.6 0.0 24 5.1 0.0 3.1 3 1 0 3 3 3 0 Helix-hairpin-helix domain AMP-binding PF00501.23 OAJ29016.1 - 9.3e-78 261.4 0.3 6.9e-56 189.4 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ29016.1 - 6.6e-10 39.7 0.0 1.7e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.1 OAJ29016.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain ETF PF01012.16 OAJ29016.1 - 0.043 13.5 0.1 0.08 12.6 0.1 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein domain DUF202 PF02656.10 OAJ29017.1 - 8.4e-15 54.7 0.3 3.9e-14 52.6 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF202) UPF0061 PF02696.9 OAJ29018.1 - 2.2e-79 267.0 0.0 3.8e-79 266.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Bac_luciferase PF00296.15 OAJ29019.1 - 2.4e-62 210.7 0.8 3.2e-62 210.4 0.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase UPF0233 PF06781.7 OAJ29021.1 - 0.049 13.2 0.4 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Rifin_STEVOR PF02009.11 OAJ29021.1 - 0.094 12.3 5.9 0.52 9.8 0.0 2.1 1 1 1 2 2 2 0 Rifin/stevor family MLANA PF14991.1 OAJ29021.1 - 0.14 12.1 0.3 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein melan-A OppC_N PF12911.2 OAJ29021.1 - 0.17 11.2 0.2 0.41 10.0 0.2 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF2029 PF09594.5 OAJ29021.1 - 2.5 7.5 12.3 0.079 12.4 3.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) C2 PF00168.25 OAJ29022.1 - 9.6e-11 41.3 0.0 2.4e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 C2 domain 4HBT PF03061.17 OAJ29023.1 - 1e-07 31.9 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily zf-RING_6 PF14835.1 OAJ29023.1 - 0.094 12.5 1.9 0.33 10.7 1.1 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein UQ_con PF00179.21 OAJ29024.1 - 1e-38 131.9 0.0 1.4e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 OAJ29024.1 - 0.041 13.7 0.1 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 OAJ29024.1 - 0.049 13.3 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 UEV domain MFS_1 PF07690.11 OAJ29025.1 - 9.1e-21 73.9 38.5 1.7e-13 50.0 15.7 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 OAJ29025.1 - 1.8e-12 47.0 4.9 1.8e-12 47.0 3.4 2.6 2 1 0 2 2 2 1 Nodulin-like zf-CCHH PF10283.4 OAJ29025.1 - 0.026 14.3 2.3 0.049 13.4 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger (CX5CX6HX5H) motif DUF3464 PF11947.3 OAJ29025.1 - 0.62 9.5 2.6 2.8 7.3 1.8 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Lustrin_cystein PF14625.1 OAJ29025.1 - 0.89 9.6 2.7 1.6 8.9 1.9 1.3 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain XFP_N PF09364.5 OAJ29027.1 - 6.6e-124 413.2 0.4 3.2e-103 345.2 0.0 2.1 2 0 0 2 2 2 2 XFP N-terminal domain XFP_C PF09363.5 OAJ29027.1 - 4e-53 179.8 0.0 3.4e-39 134.3 0.0 2.3 2 0 0 2 2 2 2 XFP C-terminal domain XFP PF03894.10 OAJ29027.1 - 3.7e-49 166.7 0.0 7.5e-49 165.7 0.0 1.5 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.16 OAJ29027.1 - 0.0094 15.5 0.3 0.022 14.3 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PI3_PI4_kinase PF00454.22 OAJ29028.1 - 3.2e-51 174.0 0.0 6.2e-51 173.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 OAJ29028.1 - 1e-31 110.1 0.0 2.1e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.8 OAJ29028.1 - 1.1e-19 70.3 0.0 6.3e-19 67.9 0.0 2.4 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 OAJ29028.1 - 2.9e-08 32.9 0.0 7e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.3 OAJ29028.1 - 0.0039 17.1 0.0 0.016 15.1 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) HEAT_EZ PF13513.1 OAJ29028.1 - 0.2 12.2 8.5 1.8 9.1 1.5 4.5 4 0 0 4 4 4 0 HEAT-like repeat DRMBL PF07522.9 OAJ29029.1 - 7.3e-27 93.5 0.0 1.5e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 OAJ29029.1 - 2.5e-06 27.1 0.0 1.1e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain zf-C2HC_2 PF13913.1 OAJ29029.1 - 0.00093 18.7 4.1 0.0017 17.9 0.6 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type Lactamase_B PF00753.22 OAJ29029.1 - 0.0082 15.8 0.2 0.02 14.5 0.1 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily CcdB PF01845.12 OAJ29029.1 - 0.23 11.3 0.0 0.43 10.5 0.0 1.4 1 0 0 1 1 1 0 CcdB protein Rad60-SLD_2 PF13881.1 OAJ29030.1 - 1.5e-10 40.9 0.0 2.8e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MTBP_C PF14920.1 OAJ29030.1 - 0.93 8.9 5.5 1.5 8.2 3.8 1.3 1 0 0 1 1 1 0 MDM2-binding Mucin PF01456.12 OAJ29030.1 - 1.7 8.3 8.7 3 7.6 6.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2361 PF10153.4 OAJ29031.1 - 7.2e-18 64.8 5.3 2.1e-17 63.3 3.7 1.8 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2361) Sigma70_ner PF04546.8 OAJ29031.1 - 0.83 9.2 20.3 2.7 7.5 2.4 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Spt5_N PF11942.3 OAJ29031.1 - 1.3 9.7 18.3 0.084 13.4 5.5 3.1 2 1 1 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal NOA36 PF06524.7 OAJ29031.1 - 2.5 7.2 6.7 4.7 6.3 4.7 1.4 1 0 0 1 1 1 0 NOA36 protein CCDC-167 PF15188.1 OAJ29031.1 - 3.8 7.5 6.0 0.66 9.9 0.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Mito_carr PF00153.22 OAJ29032.1 - 7e-66 217.9 0.6 4.6e-25 87.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rhomboid PF01694.17 OAJ29033.1 - 1.2e-06 28.6 13.8 0.00064 19.7 0.4 2.9 2 1 0 2 2 2 2 Rhomboid family Mitochondr_Som1 PF11093.3 OAJ29034.1 - 3.1e-06 26.9 0.3 4.5e-06 26.3 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Mito_carr PF00153.22 OAJ29035.1 - 7.5e-57 189.0 4.2 2.3e-19 68.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Bromodomain PF00439.20 OAJ29037.1 - 2.7e-22 78.4 0.2 4.9e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 OAJ29037.1 - 2.2e-06 27.3 0.2 7.6e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 Bromodomain associated EIF_2_alpha PF07541.7 OAJ29038.1 - 1.3e-38 131.1 0.0 2.6e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 OAJ29038.1 - 1.8e-12 47.1 0.1 4.2e-12 45.9 0.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 OAJ29038.1 - 0.044 13.7 0.1 0.097 12.6 0.1 1.6 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 AP_endonuc_2 PF01261.19 OAJ29038.1 - 0.054 12.7 0.0 0.096 11.9 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Histone PF00125.19 OAJ29039.1 - 2.4e-30 104.4 0.4 3.7e-30 103.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ29039.1 - 4e-05 23.7 0.0 6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAJ29039.1 - 0.028 14.4 0.1 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 OAJ29039.1 - 0.055 12.7 0.8 0.085 12.0 0.6 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 OAJ29039.1 - 0.087 12.5 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated GDA1_CD39 PF01150.12 OAJ29040.1 - 8.5e-98 327.6 0.0 1.2e-97 327.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family SNF2_N PF00176.18 OAJ29041.1 - 1.8e-46 158.2 0.0 3.1e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ29041.1 - 9e-13 47.8 0.0 4.6e-11 42.4 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ29041.1 - 0.00019 20.9 0.0 0.00042 19.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ29041.1 - 0.00024 20.9 1.1 0.0013 18.6 0.0 2.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DUF1980 PF09323.5 OAJ29041.1 - 6.7 6.4 5.8 20 4.8 4.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) WD40 PF00400.27 OAJ29042.1 - 1.7e-37 125.9 3.3 7.8e-09 35.0 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 OAJ29042.1 - 3.1e-06 27.0 0.1 1.7e-05 24.5 0.1 2.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PepSY_TM_2 PF13703.1 OAJ29043.1 - 0.13 12.4 11.8 0.12 12.5 3.5 3.5 3 0 0 3 3 3 0 PepSY-associated TM helix Ribosomal_L34 PF00468.12 OAJ29044.1 - 2e-17 62.5 9.5 3.2e-17 61.9 6.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Ctr PF04145.10 OAJ29045.1 - 1.1e-37 129.2 2.0 5.2e-37 127.1 1.4 1.9 1 1 0 1 1 1 1 Ctr copper transporter family Snf7 PF03357.16 OAJ29046.1 - 9e-44 148.8 12.3 9e-44 148.8 8.5 2.0 2 0 0 2 2 2 2 Snf7 Misat_Tub_SegII PF10644.4 OAJ29046.1 - 0.039 14.0 0.2 0.086 12.8 0.1 1.6 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain DUF3508 PF12018.3 OAJ29046.1 - 0.072 12.0 4.4 0.26 10.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) LTXXQ PF07813.7 OAJ29046.1 - 2.8 8.4 10.9 0.14 12.6 3.1 2.1 3 0 0 3 3 3 0 LTXXQ motif family protein Atg14 PF10186.4 OAJ29046.1 - 8.1 5.2 8.6 9 5.1 5.5 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Dynamitin PF04912.9 OAJ29047.1 - 4.2e-07 29.1 0.0 7.3e-05 21.7 0.0 2.1 2 0 0 2 2 2 2 Dynamitin WD40 PF00400.27 OAJ29048.1 - 1e-52 174.1 13.3 1.6e-08 34.0 0.0 8.6 8 1 0 8 8 8 7 WD domain, G-beta repeat LisH PF08513.6 OAJ29048.1 - 2.9e-06 26.8 0.1 6.1e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 OAJ29048.1 - 0.0021 16.2 1.9 0.4 8.7 0.0 3.2 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 OAJ29048.1 - 0.018 14.5 0.0 8.5 5.9 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.1 OAJ29048.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus dUTPase PF00692.14 OAJ29049.1 - 1e-43 147.8 0.0 1.2e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 dUTPase Chorion_2 PF03964.10 OAJ29049.1 - 0.084 13.4 2.5 0.12 12.8 1.8 1.5 1 1 0 1 1 1 0 Chorion family 2 Ribosomal_S7 PF00177.16 OAJ29050.1 - 5.5e-39 133.0 0.7 6.8e-39 132.8 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SURF1 PF02104.10 OAJ29051.1 - 7.2e-44 150.1 0.0 1.3e-43 149.3 0.0 1.4 1 1 0 1 1 1 1 SURF1 family PWWP PF00855.12 OAJ29052.1 - 1.7e-05 24.9 0.1 3.3e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 PWWP domain ACOX PF01756.14 OAJ29053.1 - 7.1e-22 77.6 0.0 2.1e-15 56.6 0.0 2.3 2 0 0 2 2 2 2 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.19 OAJ29053.1 - 4.1e-08 33.4 0.0 1.5e-07 31.6 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CTNNBL PF08216.6 OAJ29053.1 - 0.19 11.3 0.0 0.74 9.4 0.0 1.9 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear CDC50 PF03381.10 OAJ29054.1 - 7.1e-72 241.8 0.0 9.2e-72 241.5 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF1049 PF06305.6 OAJ29054.1 - 2 7.9 4.1 0.64 9.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) PIP5K PF01504.13 OAJ29055.1 - 9.7e-44 149.3 0.0 1.4e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase p450 PF00067.17 OAJ29056.1 - 1.5e-44 152.2 0.0 2.2e-44 151.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 RHH_4 PF13467.1 OAJ29056.1 - 0.1 12.4 0.7 1.4 8.8 0.6 2.6 3 0 0 3 3 3 0 Ribbon-helix-helix domain Rifin_STEVOR PF02009.11 OAJ29056.1 - 0.28 10.7 4.4 0.51 9.9 3.0 1.4 1 0 0 1 1 1 0 Rifin/stevor family Phasin_2 PF09361.5 OAJ29056.1 - 1.1 9.2 19.2 2.9 7.9 13.3 1.7 1 0 0 1 1 1 0 Phasin protein HAD PF12710.2 OAJ29057.1 - 1.5e-08 35.0 0.0 2.9e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase SNARE_assoc PF09335.6 OAJ29058.1 - 7.5e-12 45.5 4.7 7.5e-12 45.5 3.3 2.6 3 0 0 3 3 3 1 SNARE associated Golgi protein Nop14 PF04147.7 OAJ29058.1 - 3.7 5.3 11.9 6.7 4.4 8.3 1.3 1 0 0 1 1 1 0 Nop14-like family Mic1 PF07035.7 OAJ29059.1 - 5.5 6.3 7.8 0.42 9.9 0.9 1.9 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like FKBP_C PF00254.23 OAJ29060.1 - 1.2e-32 111.8 0.0 1.3e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FDC-SP PF15215.1 OAJ29061.1 - 0.15 12.3 2.4 0.26 11.5 1.7 1.3 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide FKBP_C PF00254.23 OAJ29062.1 - 6.2e-30 103.0 0.0 7e-30 102.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Metallophos PF00149.23 OAJ29063.1 - 1.5e-10 40.8 0.0 2.5e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-C3HC4 PF00097.20 OAJ29065.1 - 4.2e-06 26.3 0.4 4.2e-06 26.3 0.3 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ29065.1 - 8.4e-06 25.7 2.3 8.4e-06 25.7 1.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ29065.1 - 7.8e-05 22.2 4.9 0.00032 20.2 0.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ29065.1 - 0.00021 21.0 7.8 0.00022 20.9 1.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 OAJ29065.1 - 0.0005 19.7 3.4 0.0027 17.3 0.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 OAJ29065.1 - 0.00095 18.9 3.0 0.0029 17.3 1.2 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 OAJ29065.1 - 0.0015 18.3 2.9 0.0015 18.3 2.0 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 OAJ29065.1 - 0.0088 15.7 2.0 0.0088 15.7 1.4 2.1 2 0 0 2 2 2 1 RING-type zinc-finger ATP-synt_ab_N PF02874.18 OAJ29065.1 - 0.11 12.7 0.7 10 6.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain FAP PF07174.6 OAJ29065.1 - 6.3 6.0 28.7 2.3 7.4 8.1 2.2 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Rhodanese PF00581.15 OAJ29066.1 - 8.8e-09 35.7 0.0 1.6e-08 34.8 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain CBFB_NFYA PF02045.10 OAJ29067.1 - 1.2e-07 32.0 4.7 6.7e-07 29.7 3.2 2.5 1 1 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B RNase_H PF00075.19 OAJ29068.1 - 4.6e-12 46.4 0.0 7.5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 RNase H Mito_carr PF00153.22 OAJ29069.1 - 3e-60 199.9 6.0 8.5e-24 83.0 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF1370 PF07114.6 OAJ29069.1 - 0.0026 17.0 0.0 0.0054 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1370) CTP_transf_2 PF01467.21 OAJ29070.1 - 5.8e-08 32.9 0.0 1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 OAJ29070.1 - 0.0069 16.0 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 FAD synthetase ANTH PF07651.11 OAJ29071.1 - 4.7e-70 235.4 0.2 4.7e-70 235.4 0.1 2.5 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.12 OAJ29071.1 - 2.4e-62 209.3 10.0 2.4e-62 209.3 6.9 4.7 5 1 0 5 5 5 1 I/LWEQ domain ENTH PF01417.15 OAJ29071.1 - 3.2e-08 33.4 2.0 4.2e-07 29.8 0.0 3.7 3 1 1 4 4 4 1 ENTH domain FlaC_arch PF05377.6 OAJ29071.1 - 5 7.1 11.3 2.5 8.0 0.4 4.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) AMP-binding PF00501.23 OAJ29072.1 - 1.4e-64 218.0 0.2 2e-64 217.5 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ29072.1 - 2.8e-18 66.6 0.1 8.8e-18 65.0 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HECT PF00632.20 OAJ29073.1 - 3.3e-96 322.1 0.0 4.2e-96 321.8 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) adh_short PF00106.20 OAJ29074.1 - 2.1e-14 53.7 0.2 3e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ29074.1 - 6.5e-05 22.6 0.2 9.1e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAJ29074.1 - 0.0001 22.3 0.1 0.00027 21.0 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 OAJ29074.1 - 0.0007 19.4 0.0 0.0017 18.1 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAJ29074.1 - 0.0064 15.9 0.0 0.012 15.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 OAJ29074.1 - 0.098 11.7 0.1 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SMN PF06003.7 OAJ29075.1 - 0.00026 20.1 0.1 0.00026 20.1 0.1 1.9 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 OAJ29075.1 - 0.0016 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Tudor domain PWWP PF00855.12 OAJ29075.1 - 0.0066 16.6 1.1 0.062 13.5 0.0 2.3 2 0 0 2 2 2 1 PWWP domain LBR_tudor PF09465.5 OAJ29075.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Peptidase_S24 PF00717.18 OAJ29076.1 - 2.3e-05 23.9 0.3 0.00023 20.7 0.2 2.2 1 1 0 1 1 1 1 Peptidase S24-like Rhomboid PF01694.17 OAJ29077.1 - 3.2e-20 72.6 1.2 5.9e-20 71.7 0.8 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.5 OAJ29077.1 - 0.0015 18.7 0.1 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) RabGAP-TBC PF00566.13 OAJ29078.1 - 2.3e-49 167.8 0.0 4e-49 166.9 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Nucleo_P87 PF07267.6 OAJ29078.1 - 0.91 8.1 7.0 0.06 12.0 0.7 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 PfkB PF00294.19 OAJ29079.1 - 4e-41 141.0 0.1 5.6e-41 140.6 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Sugar_tr PF00083.19 OAJ29080.1 - 1.1e-46 159.3 14.9 1.3e-46 159.1 10.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ29080.1 - 2.1e-24 85.9 25.9 1.5e-15 56.7 7.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Spin-Ssty PF02513.12 OAJ29080.1 - 0.14 11.6 0.1 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 Spin/Ssty Family Peptidase_C13 PF01650.13 OAJ29082.1 - 2.5e-43 148.2 0.4 3.6e-43 147.7 0.3 1.2 1 0 0 1 1 1 1 Peptidase C13 family His_Phos_2 PF00328.17 OAJ29083.1 - 2.6e-40 138.8 0.0 5.7e-40 137.7 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) YtpI PF14007.1 OAJ29083.1 - 0.087 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 YtpI-like protein Peptidase_S8 PF00082.17 OAJ29084.1 - 0.43 9.6 5.7 0.54 9.3 3.9 1.1 1 0 0 1 1 1 0 Subtilase family zf-CCHC PF00098.18 OAJ29085.1 - 4.9e-15 54.6 16.8 0.00062 19.5 0.4 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ29085.1 - 6.6e-08 32.0 16.1 0.015 14.9 0.3 4.5 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ29085.1 - 1.3e-06 27.7 10.3 0.033 13.6 0.1 4.5 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ29085.1 - 0.34 10.6 5.5 8.9 6.1 0.3 3.7 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_5 PF14787.1 OAJ29085.1 - 3.2 7.3 13.0 13 5.3 0.0 4.3 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger DUF1903 PF08991.5 OAJ29086.1 - 2.5e-06 27.5 2.7 3.6e-06 27.0 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 OAJ29086.1 - 8.5e-06 25.5 4.0 1.2e-05 25.0 2.8 1.2 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.8 OAJ29086.1 - 0.00042 19.6 1.8 0.00054 19.3 1.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX6B PF02297.12 OAJ29086.1 - 0.0024 17.8 2.6 0.0036 17.2 1.8 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb UPF0203 PF05254.7 OAJ29086.1 - 0.064 13.1 2.8 0.16 11.8 2.0 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 OAJ29086.1 - 0.11 12.5 3.6 0.19 11.7 2.5 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 OAJ29086.1 - 0.62 9.8 5.4 5.9 6.7 0.9 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like EamA PF00892.15 OAJ29087.1 - 0.00015 21.8 6.2 0.00015 21.8 4.3 3.4 3 2 0 3 3 3 1 EamA-like transporter family DUF1003 PF06210.6 OAJ29087.1 - 0.02 14.8 0.0 0.02 14.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) EPSP_synthase PF00275.15 OAJ29088.1 - 9.5e-107 356.9 0.0 1.4e-106 356.4 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 OAJ29088.1 - 1.1e-95 319.4 0.0 3.5e-95 317.8 0.0 1.8 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 OAJ29088.1 - 1.1e-48 165.8 0.0 1.9e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 OAJ29088.1 - 5.8e-23 80.7 0.0 2.4e-22 78.7 0.0 2.1 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 OAJ29088.1 - 1.1e-21 77.3 0.0 2.6e-20 72.8 0.0 2.8 3 1 0 3 3 3 1 Shikimate kinase Shikimate_DH PF01488.15 OAJ29088.1 - 1.3e-10 41.5 0.0 2.8e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 OAJ29088.1 - 1.2e-05 24.7 0.0 3e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase rRNA_proc-arch PF13234.1 OAJ29090.1 - 1.8e-78 263.3 0.1 2.9e-78 262.7 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 OAJ29090.1 - 1.1e-56 190.9 1.1 2.6e-56 189.7 0.7 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 OAJ29090.1 - 1.3e-21 76.7 0.0 4.1e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ29090.1 - 4e-06 26.5 0.0 1.2e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IU_nuc_hydro PF01156.14 OAJ29091.1 - 8.6e-93 310.9 0.0 1e-92 310.7 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase VHS PF00790.14 OAJ29092.1 - 5.7e-41 139.4 0.0 1.6e-40 138.0 0.0 1.7 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 OAJ29092.1 - 2.5e-20 72.3 0.0 6.2e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 GAT domain Spc97_Spc98 PF04130.8 OAJ29093.1 - 1.8e-108 363.2 0.0 2.9e-108 362.5 0.0 1.4 1 1 0 1 1 1 1 Spc97 / Spc98 family Nop53 PF07767.6 OAJ29093.1 - 0.0036 16.3 9.8 0.0036 16.3 6.8 1.8 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) DUF4484 PF14831.1 OAJ29093.1 - 0.0099 15.9 6.2 1.8 8.6 2.6 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4484) Apt1 PF10351.4 OAJ29093.1 - 0.12 11.2 3.6 0.25 10.1 2.5 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.9 OAJ29093.1 - 1.4 6.8 19.4 2.4 6.0 13.4 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 OAJ29093.1 - 1.6 8.3 21.3 5.1 6.6 14.8 1.8 1 0 0 1 1 1 0 YL1 nuclear protein HSP90 PF00183.13 OAJ29093.1 - 4.3 5.6 10.0 8 4.7 6.9 1.3 1 0 0 1 1 1 0 Hsp90 protein Nucleoporin_FG PF13634.1 OAJ29094.1 - 0.0015 18.7 28.8 0.0015 18.7 20.0 3.4 2 1 1 3 3 3 2 Nucleoporin FG repeat region RR_TM4-6 PF06459.7 OAJ29094.1 - 6.8 6.5 15.0 13 5.6 10.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HCO3_cotransp PF00955.16 OAJ29095.1 - 5.4e-40 137.5 16.5 8e-22 77.5 4.1 3.1 2 1 1 3 3 3 3 HCO3- transporter family Acyl-CoA_dh_1 PF00441.19 OAJ29096.1 - 9e-46 155.6 5.0 9e-46 155.6 3.5 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAJ29096.1 - 2.5e-27 95.7 0.0 7.5e-27 94.1 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAJ29096.1 - 1.8e-22 79.9 2.6 1.8e-22 79.9 1.8 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ29096.1 - 5.3e-18 64.2 0.0 1e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain RasGAP PF00616.14 OAJ29097.1 - 4.4e-24 85.2 0.0 4.2e-23 82.0 0.0 2.0 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 OAJ29097.1 - 0.00051 19.8 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF1115 PF06544.7 OAJ29098.1 - 1.6e-11 44.0 0.0 2.2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF2638 PF10937.3 OAJ29098.1 - 0.063 14.2 0.9 0.14 13.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) Acyl-CoA_dh_N PF02771.11 OAJ29099.1 - 6.4e-28 97.5 0.1 1.3e-27 96.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 OAJ29099.1 - 1.1e-23 84.0 0.0 2.2e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ29099.1 - 5.7e-18 64.1 0.0 1.3e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 OAJ29099.1 - 2.9e-05 24.3 0.0 2.9e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Spc24 PF08286.6 OAJ29100.1 - 1.1 9.0 3.2 0.35 10.5 0.1 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 PTH2 PF01981.11 OAJ29101.1 - 2.2e-05 24.1 0.1 4e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 AAA_2 PF07724.9 OAJ29102.1 - 2.6e-43 147.9 0.0 4.2e-40 137.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 OAJ29102.1 - 9.8e-26 89.4 1.0 3.2e-25 87.8 0.0 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 OAJ29102.1 - 7e-20 71.5 0.0 2.8e-10 40.4 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAJ29102.1 - 4.6e-11 42.4 0.1 1.2e-07 31.3 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ29102.1 - 6.5e-11 42.1 0.0 8.5e-06 25.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 OAJ29102.1 - 1.4e-09 38.1 14.9 0.00041 20.3 0.0 5.3 4 3 1 6 6 5 3 AAA ATPase domain AAA_22 PF13401.1 OAJ29102.1 - 1.3e-07 31.8 1.4 0.0026 17.9 0.0 4.2 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 OAJ29102.1 - 2e-06 27.4 0.0 0.075 12.7 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 OAJ29102.1 - 8.9e-06 25.6 0.2 0.013 15.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 OAJ29102.1 - 1.6e-05 25.2 0.0 0.14 12.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 OAJ29102.1 - 6.8e-05 22.0 0.0 0.028 13.5 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 OAJ29102.1 - 7.6e-05 23.5 0.2 0.3 11.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.4 OAJ29102.1 - 0.00011 20.9 0.1 0.32 9.5 0.0 2.7 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.16 OAJ29102.1 - 0.00012 21.2 0.0 0.26 10.4 0.0 3.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 OAJ29102.1 - 0.00024 20.7 0.0 0.14 11.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF853 PF05872.7 OAJ29102.1 - 0.00034 19.0 1.7 0.19 10.0 0.0 2.7 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF853) TIP49 PF06068.8 OAJ29102.1 - 0.00041 19.1 0.5 0.071 11.8 0.0 3.0 3 0 0 3 3 3 1 TIP49 C-terminus ResIII PF04851.10 OAJ29102.1 - 0.00042 20.1 1.1 0.66 9.7 0.0 3.5 2 2 2 4 4 3 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 OAJ29102.1 - 0.00064 19.7 2.6 0.99 9.3 0.0 3.9 4 1 0 4 4 4 1 AAA domain Arch_ATPase PF01637.13 OAJ29102.1 - 0.00082 19.1 4.1 0.058 13.0 0.1 3.4 3 1 0 3 3 2 1 Archaeal ATPase NACHT PF05729.7 OAJ29102.1 - 0.0011 18.6 0.3 0.47 10.1 0.0 3.1 3 0 0 3 3 3 1 NACHT domain T2SE PF00437.15 OAJ29102.1 - 0.0011 17.8 0.0 0.025 13.4 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 OAJ29102.1 - 0.0016 18.1 0.0 0.66 9.6 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 OAJ29102.1 - 0.0022 17.4 0.0 1.6 8.1 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 OAJ29102.1 - 0.004 17.3 0.1 2.9 8.1 0.0 2.9 3 0 0 3 3 2 1 RNA helicase Torsin PF06309.6 OAJ29102.1 - 0.0052 16.6 0.0 0.039 13.8 0.0 2.1 2 0 0 2 2 2 1 Torsin SRP54 PF00448.17 OAJ29102.1 - 0.0073 15.7 0.1 2.2 7.6 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CENP-F_leu_zip PF10473.4 OAJ29102.1 - 0.0075 16.1 10.7 0.016 15.0 7.4 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2075 PF09848.4 OAJ29102.1 - 0.011 14.7 1.7 0.055 12.4 0.0 2.7 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) IncA PF04156.9 OAJ29102.1 - 0.014 14.9 6.8 0.033 13.7 4.7 1.6 1 0 0 1 1 1 0 IncA protein AAA_33 PF13671.1 OAJ29102.1 - 0.03 14.1 0.2 11 5.8 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.1 OAJ29102.1 - 0.034 13.5 2.8 8.3 5.7 0.0 3.5 3 1 0 4 4 3 0 AAA domain AAA_3 PF07726.6 OAJ29102.1 - 0.04 13.5 0.0 0.4 10.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.16 OAJ29102.1 - 0.049 12.9 0.1 0.049 12.9 0.0 3.4 2 1 0 2 2 1 0 UvrD/REP helicase N-terminal domain FadA PF09403.5 OAJ29102.1 - 0.052 13.5 3.5 0.14 12.1 2.4 1.7 1 0 0 1 1 1 0 Adhesion protein FadA PhoH PF02562.11 OAJ29102.1 - 0.071 12.3 0.1 7.1 5.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein UPF0079 PF02367.12 OAJ29102.1 - 0.12 12.0 0.0 13 5.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF4266 PF14086.1 OAJ29102.1 - 0.22 12.0 5.8 0.65 10.5 2.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) DUF87 PF01935.12 OAJ29102.1 - 0.36 10.5 5.2 4.3 7.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_23 PF13476.1 OAJ29102.1 - 1.6 9.0 12.3 1.9 8.8 0.0 3.4 2 1 0 2 2 1 0 AAA domain Elong_Iki1 PF10483.4 OAJ29103.1 - 2.2e-11 43.6 0.2 5.9e-05 22.5 0.1 2.4 2 0 0 2 2 2 2 Elongator subunit Iki1 DUF1077 PF06417.7 OAJ29104.1 - 8e-48 160.9 0.4 1.1e-47 160.4 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF4658 PF15555.1 OAJ29104.1 - 0.33 10.8 2.0 2.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) Slu7 PF11708.3 OAJ29105.1 - 2.1e-80 269.9 17.5 2.1e-80 269.9 12.1 3.2 2 2 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor Elongin_A PF06881.6 OAJ29106.1 - 2.9e-26 91.9 0.3 4.9e-26 91.2 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Zn_clus PF00172.13 OAJ29107.1 - 1.9e-06 27.6 9.1 3.4e-06 26.8 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAJ29107.1 - 0.00085 18.2 0.2 0.00085 18.2 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain B3_4 PF03483.12 OAJ29108.1 - 1.5e-27 96.1 0.0 3.2e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 OAJ29108.1 - 1.1e-18 66.8 0.0 1.1e-16 60.3 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF382 PF04037.8 OAJ29110.1 - 2.2e-55 185.9 0.1 3.8e-55 185.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 OAJ29110.1 - 2.3e-20 71.6 6.1 4.8e-20 70.6 4.3 1.6 1 0 0 1 1 1 1 PSP PBP1_TM PF14812.1 OAJ29110.1 - 2.4 8.5 30.6 0.45 10.8 2.1 3.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Thioredoxin_4 PF13462.1 OAJ29111.1 - 5.5e-07 29.7 0.0 2.9e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin PDZ_2 PF13180.1 OAJ29112.1 - 1.2e-05 25.1 0.0 2.9e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.19 OAJ29112.1 - 0.00043 20.4 0.0 0.00099 19.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 OAJ29112.1 - 0.096 12.6 0.0 0.3 11.0 0.0 1.7 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain Cnd3 PF12719.2 OAJ29113.1 - 6.8e-79 264.9 0.0 6.5e-76 255.1 0.0 3.1 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 OAJ29113.1 - 9.1e-06 25.8 16.8 0.00068 19.8 1.2 6.0 5 1 1 6 6 6 3 HEAT repeats HEAT PF02985.17 OAJ29113.1 - 0.00057 19.7 6.1 21 5.5 0.0 6.9 8 0 0 8 8 8 2 HEAT repeat FANCI_S2 PF14676.1 OAJ29113.1 - 0.017 15.0 0.2 5.5 6.8 0.0 2.7 2 0 0 2 2 2 0 FANCI solenoid 2 Cnd1 PF12717.2 OAJ29113.1 - 0.03 14.1 2.3 0.97 9.2 0.1 3.3 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 OAJ29113.1 - 0.042 14.3 9.6 34 5.1 0.0 6.2 5 0 0 5 5 5 0 HEAT-like repeat Homeobox PF00046.24 OAJ29114.1 - 6.1e-19 67.3 4.8 1.2e-18 66.5 3.4 1.5 1 0 0 1 1 1 1 Homeobox domain Transket_pyr PF02779.19 OAJ29115.1 - 6.8e-61 204.8 0.0 1e-60 204.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 OAJ29115.1 - 2.7e-59 200.3 0.0 4.4e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component ACBP PF00887.14 OAJ29117.1 - 2.7e-26 91.0 0.0 4.1e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Nucleoplasmin PF03066.10 OAJ29117.1 - 0.19 11.2 7.4 0.36 10.3 5.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin Menin PF05053.8 OAJ29117.1 - 0.23 9.5 0.7 0.34 9.0 0.5 1.1 1 0 0 1 1 1 0 Menin Myc_N PF01056.13 OAJ29117.1 - 0.89 8.6 5.5 1.4 7.9 3.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 OAJ29117.1 - 0.92 7.9 8.3 1.3 7.4 5.8 1.0 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 OAJ29117.1 - 2.1 7.9 7.4 3.2 7.4 5.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.8 OAJ29117.1 - 5.6 6.5 7.1 10 5.6 4.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 OAJ29117.1 - 6.5 5.9 5.7 9.8 5.3 4.0 1.2 1 0 0 1 1 1 0 NOA36 protein PI3Ka PF00613.15 OAJ29118.1 - 7.7e-53 178.4 0.0 1.2e-52 177.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 OAJ29118.1 - 1.6e-43 148.8 0.0 3.2e-42 144.6 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 OAJ29118.1 - 5.7e-34 116.9 0.0 9.1e-34 116.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.25 OAJ29118.1 - 0.0056 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain Caudo_TAP PF02413.12 OAJ29120.1 - 1.2 9.2 7.3 3.1 7.9 5.0 1.6 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein Transketolase_N PF00456.16 OAJ29122.1 - 2.3e-17 62.8 2.7 1.3e-15 57.0 1.8 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 OAJ29122.1 - 9.9e-11 41.6 0.0 3.4e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 OAJ29122.1 - 3.4e-05 23.4 0.0 8.2e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 OAJ29122.1 - 0.012 14.3 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 OAJ29122.1 - 0.1 12.1 0.2 0.46 10.0 0.0 2.1 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Elf1 PF05129.8 OAJ29123.1 - 4.5e-25 87.1 2.3 5.3e-25 86.9 1.6 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.1 OAJ29123.1 - 0.04 14.2 2.7 0.057 13.7 1.8 1.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar ABC_membrane_2 PF06472.10 OAJ29124.1 - 3.6e-101 337.9 4.2 4.7e-101 337.6 2.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 OAJ29124.1 - 5.2e-20 72.1 0.0 1.7e-19 70.4 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 OAJ29124.1 - 0.00022 21.3 0.1 0.00057 19.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 OAJ29124.1 - 0.014 14.6 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 OAJ29124.1 - 0.016 15.2 0.0 0.055 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 OAJ29124.1 - 0.022 15.0 3.3 0.16 12.2 2.3 2.2 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 OAJ29124.1 - 0.028 13.8 0.0 1.2 8.6 0.0 2.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_29 PF13555.1 OAJ29124.1 - 0.043 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 OAJ29124.1 - 0.047 12.8 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 OMPdecase PF00215.19 OAJ29125.1 - 1.4e-74 250.2 0.1 1.8e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF2508 PF10704.4 OAJ29125.1 - 0.094 12.9 0.0 0.34 11.0 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) WW PF00397.21 OAJ29126.1 - 0.0027 17.5 0.5 0.0056 16.5 0.3 1.6 1 0 0 1 1 1 1 WW domain Dynamin_M PF01031.15 OAJ29128.1 - 5.5e-104 347.0 0.0 1.5e-103 345.7 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 OAJ29128.1 - 8.7e-50 168.8 0.0 2.6e-49 167.2 0.0 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 OAJ29128.1 - 5.3e-29 99.9 5.3 5.3e-29 99.9 3.7 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain Acetyltransf_1 PF00583.19 OAJ29129.1 - 3.9e-11 42.8 0.0 6.5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ29129.1 - 3.6e-05 23.8 0.1 8.1e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ29129.1 - 5e-05 22.9 0.0 8.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 OAJ29129.1 - 0.0087 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAJ29129.1 - 0.014 15.4 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Hydrolase PF00702.21 OAJ29130.1 - 9.9e-23 81.6 0.0 1e-21 78.3 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 OAJ29130.1 - 8.1e-20 70.8 0.0 1.8e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 OAJ29130.1 - 1.2e-19 71.2 0.0 2.3e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ29130.1 - 0.00089 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAJ29130.1 - 0.0032 17.0 0.0 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 OAJ29130.1 - 0.064 12.5 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase IPP-2 PF04979.9 OAJ29131.1 - 7.5e-10 39.1 11.1 0.00037 20.7 0.0 2.5 2 1 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) PhoD PF09423.5 OAJ29132.1 - 3e-138 461.2 8.3 3.5e-138 460.9 5.8 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase HNH_2 PF13391.1 OAJ29132.1 - 0.042 13.6 0.0 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease Fork_head PF00250.13 OAJ29133.1 - 8.6e-30 102.6 0.0 1.7e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Fork head domain Abhydrolase_6 PF12697.2 OAJ29134.1 - 1e-25 90.9 0.0 1.3e-25 90.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ29134.1 - 5.1e-17 62.2 0.0 9.3e-11 41.7 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ29134.1 - 2.4e-10 40.3 0.0 3.6e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAJ29134.1 - 0.00098 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 OAJ29134.1 - 0.012 15.0 0.1 0.67 9.3 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 OAJ29134.1 - 0.044 13.3 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 OAJ29134.1 - 0.17 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Mito_carr PF00153.22 OAJ29135.1 - 1.2e-58 194.8 20.8 7.5e-23 80.0 0.0 5.0 4 1 0 4 4 4 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 OAJ29135.1 - 2.8e-05 23.0 0.2 0.00034 19.7 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 OAJ29135.1 - 0.00037 20.1 0.1 0.004 16.9 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 OAJ29135.1 - 0.0005 19.2 0.4 0.0015 17.7 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 OAJ29135.1 - 0.0007 19.6 0.5 0.0019 18.2 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair Tubulin PF00091.20 OAJ29136.1 - 9.8e-62 208.5 0.0 1.5e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 OAJ29136.1 - 7.7e-45 152.0 0.0 1.2e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 OAJ29136.1 - 0.0004 19.9 0.0 0.0008 18.9 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 OAJ29136.1 - 0.038 13.6 0.1 0.68 9.5 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) Glycos_transf_1 PF00534.15 OAJ29137.1 - 1.7e-13 50.3 0.0 9.7e-13 47.8 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 OAJ29137.1 - 6.5e-06 26.3 0.0 5.9e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 OAJ29137.1 - 0.059 13.5 0.6 0.16 12.1 0.4 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 OAJ29137.1 - 0.086 13.1 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 FCP1_C PF09309.5 OAJ29138.1 - 0.022 14.1 0.2 0.022 14.1 0.2 1.9 2 0 0 2 2 2 0 FCP1, C-terminal DUF4477 PF14780.1 OAJ29138.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) IF-2B PF01008.12 OAJ29139.1 - 1.4e-34 119.3 0.3 5.3e-31 107.6 0.0 2.8 3 0 0 3 3 3 2 Initiation factor 2 subunit family HSP90 PF00183.13 OAJ29139.1 - 3.3 5.9 6.9 4.7 5.4 4.8 1.1 1 0 0 1 1 1 0 Hsp90 protein DUF1244 PF06844.6 OAJ29140.1 - 0.084 12.7 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) RabGAP-TBC PF00566.13 OAJ29141.1 - 1.1e-21 77.3 3.3 9.4e-18 64.4 0.6 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Hydrophob_seed PF14547.1 OAJ29141.1 - 0.024 14.5 0.1 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 Hydrophobic seed protein MFS_1 PF07690.11 OAJ29142.1 - 3.2e-38 131.3 38.7 5.5e-32 110.8 12.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WCOR413 PF05562.6 OAJ29142.1 - 0.47 9.9 5.4 1.5 8.3 0.5 3.2 3 0 0 3 3 3 0 Cold acclimation protein WCOR413 DUF2484 PF10658.4 OAJ29142.1 - 0.56 10.3 11.3 0.024 14.7 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) SNF2_N PF00176.18 OAJ29144.1 - 4e-63 213.0 0.2 6.1e-63 212.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ29144.1 - 1.3e-08 34.5 0.0 2.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain XPG_I PF00867.13 OAJ29144.1 - 1.6e-08 34.4 0.0 1.6e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 XPG I-region zf-RING_5 PF14634.1 OAJ29144.1 - 1.8e-05 24.3 0.6 4.3e-05 23.1 0.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 OAJ29144.1 - 0.001 18.8 0.7 0.0022 17.7 0.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ29144.1 - 0.0012 18.8 4.1 0.0021 18.0 1.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ29144.1 - 0.0017 17.9 0.7 0.0017 17.9 0.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) XPG_N PF00752.12 OAJ29144.1 - 0.0051 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 OAJ29144.1 - 0.02 15.0 0.0 0.078 13.2 0.0 2.0 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold zf-RING_UBOX PF13445.1 OAJ29144.1 - 0.044 13.5 0.1 0.099 12.3 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 OAJ29144.1 - 0.078 12.8 1.4 0.26 11.1 1.0 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Glypican PF01153.14 OAJ29144.1 - 0.41 9.1 2.8 4.2 5.8 2.9 1.9 2 0 0 2 2 2 0 Glypican Metallopep PF12044.3 OAJ29145.1 - 9.7e-85 284.5 0.0 1.8e-33 115.6 0.0 3.0 3 0 0 3 3 3 3 Putative peptidase family Jacalin PF01419.12 OAJ29145.1 - 0.00063 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain Peptidase_M66 PF10462.4 OAJ29145.1 - 0.0016 17.4 0.5 0.0027 16.6 0.4 1.3 1 0 0 1 1 1 1 Peptidase M66 Choline_kinase PF01633.15 OAJ29146.1 - 1.8e-33 115.8 0.0 1.6e-22 80.1 0.0 2.9 3 1 0 3 3 3 2 Choline/ethanolamine kinase APH PF01636.18 OAJ29146.1 - 0.00094 18.9 0.8 0.038 13.7 0.0 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family GCV_T PF01571.16 OAJ29149.1 - 2.5e-66 223.0 0.0 3.3e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 OAJ29149.1 - 1e-24 86.3 0.0 2.1e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 OAJ29149.1 - 0.0015 18.4 0.0 0.016 15.0 0.0 2.3 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family Thymidylate_kin PF02223.12 OAJ29150.1 - 6e-44 149.6 0.0 7.5e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 OAJ29150.1 - 4.2e-06 26.8 0.0 7.2e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 OAJ29150.1 - 0.0014 17.9 0.0 0.0037 16.5 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 OAJ29150.1 - 0.0097 15.7 0.4 0.074 12.9 0.3 2.4 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 OAJ29150.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 OAJ29150.1 - 0.025 14.5 1.0 0.1 12.5 0.7 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 OAJ29150.1 - 0.065 14.0 0.1 0.16 12.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.20 OAJ29151.1 - 1.1e-67 228.2 0.0 1.3e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Adeno_PVIII PF01310.13 OAJ29151.1 - 0.0091 15.8 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 1 Adenovirus hexon associated protein, protein VIII RCC1 PF00415.13 OAJ29152.1 - 1.3e-16 60.5 12.2 0.0006 19.9 0.0 7.3 6 3 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ29152.1 - 4.1e-12 45.3 14.6 0.029 14.0 0.0 7.9 8 1 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat L51_S25_CI-B8 PF05047.11 OAJ29153.1 - 8.6e-11 41.4 0.0 1.1e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Acatn PF13000.2 OAJ29155.1 - 1.3e-141 472.7 29.6 6e-71 239.6 8.4 4.4 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Pkinase PF00069.20 OAJ29158.1 - 8.2e-65 218.5 0.0 3.8e-64 216.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ29158.1 - 5e-34 117.5 0.0 1.1e-33 116.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 OAJ29158.1 - 1.5e-28 98.3 15.1 1.3e-17 63.2 5.6 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 OAJ29158.1 - 8.1e-21 73.5 22.7 3.6e-11 42.6 6.4 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 OAJ29158.1 - 1.6e-08 34.8 2.3 6.3e-08 33.0 1.6 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 OAJ29158.1 - 0.0032 16.4 0.0 0.007 15.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Uds1 PF15456.1 OAJ29158.1 - 0.19 11.7 7.3 0.14 12.1 1.9 2.4 2 0 0 2 2 2 0 Up-regulated During Septation DUF2937 PF11157.3 OAJ29158.1 - 0.3 10.4 7.7 1.1 8.5 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) FYVE_2 PF02318.11 OAJ29158.1 - 4.9 7.0 17.3 14 5.6 4.8 2.9 2 1 1 3 3 3 0 FYVE-type zinc finger DEAD PF00270.24 OAJ29160.1 - 1.2e-12 47.6 0.0 2.5e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ29160.1 - 1.6e-07 31.0 0.0 1e-06 28.4 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Calpain_III PF01067.17 OAJ29160.1 - 0.19 11.3 1.1 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Calpain large subunit, domain III Astro_capsid PF03115.9 OAJ29161.1 - 0.00051 18.4 4.2 0.0076 14.5 0.6 2.0 1 1 1 2 2 2 2 Astrovirus capsid protein precursor TFIIA PF03153.8 OAJ29161.1 - 0.0037 17.2 4.9 0.0037 17.2 3.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.3 OAJ29161.1 - 0.063 13.2 11.6 0.1 12.5 8.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RNA_pol_Rpb2_7 PF04560.15 OAJ29161.1 - 0.11 12.8 0.1 0.3 11.3 0.0 1.7 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 7 Pox_Ag35 PF03286.9 OAJ29161.1 - 0.33 10.4 4.3 0.48 9.9 3.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Daxx PF03344.10 OAJ29161.1 - 6.3 5.1 14.3 8.7 4.6 9.9 1.2 1 0 0 1 1 1 0 Daxx Family ABC2_membrane PF01061.19 OAJ29162.1 - 3.2e-36 124.4 19.1 3.2e-36 124.4 13.2 2.1 3 0 0 3 3 2 1 ABC-2 type transporter ABC_tran PF00005.22 OAJ29162.1 - 8e-25 87.7 0.0 1.3e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 OAJ29162.1 - 2.3e-09 37.6 0.0 1.9e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 OAJ29162.1 - 2.1e-05 23.7 25.7 5.2e-05 22.4 17.8 1.7 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 OAJ29162.1 - 0.0008 18.8 0.1 0.022 14.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ29162.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 OAJ29162.1 - 0.021 14.3 0.1 0.073 12.6 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 OAJ29162.1 - 0.025 15.3 0.0 0.047 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 OAJ29162.1 - 0.025 13.6 0.0 6 5.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 OAJ29162.1 - 0.041 14.1 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 OAJ29162.1 - 0.058 12.5 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 OAJ29162.1 - 0.083 12.8 0.0 0.52 10.2 0.0 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.10 OAJ29162.1 - 0.088 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 OAJ29162.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 OAJ29162.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 OAJ29162.1 - 0.23 11.4 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 OAJ29162.1 - 0.23 11.7 0.1 0.41 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 OAJ29162.1 - 0.23 11.1 0.0 0.44 10.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DASH_Spc19 PF08287.6 OAJ29163.1 - 0.002 17.7 0.0 0.0026 17.3 0.0 1.1 1 0 0 1 1 1 1 Spc19 Pkinase PF00069.20 OAJ29165.1 - 9.3e-57 192.1 0.0 1.4e-56 191.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ29165.1 - 7.9e-19 67.7 0.0 1.5e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 OAJ29165.1 - 0.0051 16.1 0.1 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 OAJ29165.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 OAJ29165.1 - 0.12 11.9 0.2 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Nop14 PF04147.7 OAJ29165.1 - 0.82 7.5 23.9 0.056 11.3 4.2 2.3 2 0 0 2 2 2 0 Nop14-like family VID27 PF08553.5 OAJ29165.1 - 6.7 4.7 6.0 19 3.3 4.1 1.7 1 0 0 1 1 1 0 VID27 cytoplasmic protein Exo_endo_phos_2 PF14529.1 OAJ29166.1 - 6.6e-17 61.2 0.0 1.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase OLF PF02191.11 OAJ29170.1 - 0.057 12.6 0.1 0.065 12.4 0.1 1.0 1 0 0 1 1 1 0 Olfactomedin-like domain RNase_P_pop3 PF08228.6 OAJ29171.1 - 0.0023 17.7 0.0 2.3 8.0 0.0 2.5 2 0 0 2 2 2 2 RNase P subunit Pop3 GTP_EFTU PF00009.22 OAJ29173.1 - 5.7e-38 130.2 0.0 9.8e-38 129.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 OAJ29173.1 - 1.4e-37 127.6 0.4 3.5e-37 126.3 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 OAJ29173.1 - 4.1e-12 46.0 0.4 1.4e-11 44.3 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAJ29173.1 - 0.037 13.9 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Asp_Glu_race PF01177.17 OAJ29174.1 - 1.7e-24 86.9 0.1 2e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DDE_Tnp_4 PF13359.1 OAJ29177.1 - 4.7e-22 78.2 0.0 7.4e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 OAJ29177.1 - 0.0016 18.0 0.3 0.0016 18.0 0.2 3.0 3 1 0 3 3 3 1 Transposase DDE domain NAM-associated PF14303.1 OAJ29177.1 - 3.6 7.8 11.1 7.5 6.8 7.7 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Tautomerase_3 PF14832.1 OAJ29178.1 - 2.3e-37 128.0 0.0 2.6e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Glyco_hydro_16 PF00722.16 OAJ29181.1 - 5.3e-06 25.8 0.0 1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RhoGEF PF00621.15 OAJ29182.1 - 6.2e-42 143.5 0.1 1.5e-41 142.2 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 OAJ29182.1 - 5.7e-05 23.2 0.0 0.00015 21.9 0.0 1.8 1 0 0 1 1 1 1 PH domain Arteri_nucleo PF01481.11 OAJ29182.1 - 0.11 12.6 1.4 0.28 11.2 1.0 1.6 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein Cwf_Cwc_15 PF04889.7 OAJ29182.1 - 2.4 7.7 13.9 4.6 6.8 9.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SH3_1 PF00018.23 OAJ29183.1 - 8.4e-18 63.4 0.3 7.3e-09 34.8 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 OAJ29183.1 - 3.7e-17 61.6 0.1 8.5e-10 38.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.2 OAJ29183.1 - 4.4e-16 58.5 0.0 9.5e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_2 PF07653.12 OAJ29183.1 - 2.2e-10 39.8 0.0 2.2e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.15 OAJ29183.1 - 1.4e-07 30.8 0.3 1.4e-07 30.8 0.2 2.3 2 0 0 2 2 2 1 WH2 motif EF-hand_7 PF13499.1 OAJ29183.1 - 0.007 16.4 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair AAA PF00004.24 OAJ29184.1 - 9.9e-41 139.0 0.0 2.3e-40 137.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ29184.1 - 3.3e-07 30.4 0.2 0.00033 20.7 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAJ29184.1 - 1.7e-06 28.2 0.2 0.00017 21.7 0.2 2.8 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 OAJ29184.1 - 2.7e-06 26.6 0.0 4.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 OAJ29184.1 - 3e-06 27.0 0.1 3.1e-05 23.7 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 OAJ29184.1 - 8.8e-06 25.6 0.0 0.00012 21.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ29184.1 - 1.3e-05 25.9 0.0 3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 OAJ29184.1 - 7.4e-05 22.6 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ29184.1 - 0.00024 21.4 0.1 0.0012 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 OAJ29184.1 - 0.00031 20.6 0.0 0.00067 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 OAJ29184.1 - 0.0004 19.8 0.0 0.00066 19.1 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 OAJ29184.1 - 0.00067 19.1 1.6 0.037 13.4 0.4 2.2 1 1 1 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 OAJ29184.1 - 0.00081 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.8 OAJ29184.1 - 0.002 16.9 0.0 0.0038 16.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 OAJ29184.1 - 0.0022 18.1 0.0 0.0077 16.4 0.0 1.9 1 1 1 2 2 1 1 RNA helicase AAA_24 PF13479.1 OAJ29184.1 - 0.0023 17.5 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 OAJ29184.1 - 0.0028 16.8 0.2 0.0095 15.1 0.1 1.7 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 OAJ29184.1 - 0.0035 17.0 0.5 0.0082 15.8 0.4 1.6 1 0 0 1 1 1 1 Part of AAA domain Bac_DnaA PF00308.13 OAJ29184.1 - 0.0042 16.7 0.0 0.0087 15.7 0.0 1.4 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_28 PF13521.1 OAJ29184.1 - 0.0045 16.9 0.0 0.0082 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAJ29184.1 - 0.007 15.4 0.1 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF815 PF05673.8 OAJ29184.1 - 0.0084 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_21 PF13304.1 OAJ29184.1 - 0.0087 16.0 0.5 2 8.3 0.1 2.3 1 1 1 2 2 2 1 AAA domain Arch_ATPase PF01637.13 OAJ29184.1 - 0.0089 15.7 0.8 2 8.0 0.0 3.0 2 1 1 3 3 3 1 Archaeal ATPase Sigma54_activat PF00158.21 OAJ29184.1 - 0.0098 15.3 0.0 0.021 14.2 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain KaiC PF06745.8 OAJ29184.1 - 0.015 14.4 0.0 0.13 11.3 0.0 2.1 1 1 1 2 2 2 0 KaiC Parvo_NS1 PF01057.12 OAJ29184.1 - 0.018 13.9 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 OAJ29184.1 - 0.028 13.6 0.1 0.052 12.7 0.1 1.4 1 1 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.6 OAJ29184.1 - 0.044 13.3 0.1 0.17 11.5 0.0 2.0 3 0 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) S1FA PF04689.8 OAJ29184.1 - 0.065 13.1 0.2 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA Guanylate_kin PF00625.16 OAJ29184.1 - 0.077 12.4 0.0 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Guanylate kinase DUF2075 PF09848.4 OAJ29184.1 - 0.099 11.5 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 OAJ29184.1 - 0.11 12.1 0.6 0.29 10.7 0.1 2.0 3 0 0 3 3 2 0 NACHT domain IPT PF01745.11 OAJ29184.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase UPF0079 PF02367.12 OAJ29184.1 - 0.13 11.8 0.1 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 OAJ29184.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 OAJ29184.1 - 0.15 12.3 0.1 0.21 11.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter SAICAR_synt PF01259.13 OAJ29185.1 - 2.8e-76 255.9 0.0 4.2e-58 196.3 0.0 2.1 2 0 0 2 2 2 2 SAICAR synthetase Pro-kuma_activ PF09286.6 OAJ29185.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain SCA7 PF08313.7 OAJ29186.1 - 7e-26 89.6 0.2 1.8e-25 88.3 0.1 1.6 1 0 0 1 1 1 1 SCA7, zinc-binding domain Abhydrolase_6 PF12697.2 OAJ29187.1 - 1.3e-11 44.8 0.8 7.6e-05 22.6 0.6 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ29187.1 - 2.2e-11 43.6 0.1 3.2e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 OAJ29187.1 - 1.8e-08 34.1 0.1 1.3e-05 24.7 0.0 2.1 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 OAJ29187.1 - 8.7e-08 31.9 0.1 0.0079 15.7 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 OAJ29187.1 - 0.042 13.2 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 OAJ29187.1 - 0.046 13.5 0.1 0.13 12.1 0.0 1.9 1 1 0 1 1 1 0 Putative lysophospholipase PC_rep PF01851.17 OAJ29188.1 - 2.4e-45 150.2 17.6 3.7e-09 36.3 0.0 10.1 10 0 0 10 10 10 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 OAJ29188.1 - 4.6e-22 78.1 7.3 3.2e-11 43.3 0.0 5.0 2 1 4 6 6 6 5 HEAT repeats HEAT PF02985.17 OAJ29188.1 - 2.1e-07 30.4 2.5 1.4 9.2 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 OAJ29188.1 - 2.4e-07 31.0 8.3 0.025 15.0 0.1 5.5 4 1 2 6 6 6 3 HEAT-like repeat HEAT_PBS PF03130.11 OAJ29188.1 - 0.0035 17.6 2.1 59 4.5 0.0 5.9 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat DUF3439 PF11921.3 OAJ29188.1 - 1.5 8.5 4.0 3.5 7.4 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TPR_19 PF14559.1 OAJ29188.1 - 2 8.8 9.6 3.2 8.1 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RRN3 PF05327.6 OAJ29189.1 - 0.24 9.4 0.3 0.46 8.5 0.2 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_M43 PF05572.8 OAJ29190.1 - 9.7e-08 31.7 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Oxidored-like PF09791.4 OAJ29190.1 - 1.6e-05 24.2 4.2 3.2e-05 23.2 2.9 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Pro-kuma_activ PF09286.6 OAJ29191.1 - 1e-16 61.2 0.0 2.4e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 OAJ29191.1 - 1.6e-13 50.4 0.7 4.5e-13 48.9 0.3 1.6 1 1 0 1 1 1 1 Subtilase family OmpA PF00691.15 OAJ29191.1 - 0.12 12.7 0.0 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 OmpA family IPPT PF01715.12 OAJ29192.1 - 1.6e-36 125.6 0.0 4.6e-22 78.2 0.0 3.0 2 1 0 2 2 2 2 IPP transferase AAA_17 PF13207.1 OAJ29192.1 - 0.00011 22.9 0.0 0.0008 20.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAJ29192.1 - 0.0024 18.0 0.0 0.0085 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ29192.1 - 0.0037 17.5 0.1 0.05 13.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 OAJ29192.1 - 0.005 16.8 0.6 0.05 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 OAJ29192.1 - 0.014 15.0 0.0 0.042 13.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 OAJ29192.1 - 0.031 13.5 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein IPT PF01745.11 OAJ29192.1 - 0.049 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase AAA_33 PF13671.1 OAJ29192.1 - 0.059 13.2 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 OAJ29192.1 - 0.065 13.1 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAJ29192.1 - 0.067 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 OAJ29192.1 - 0.12 11.3 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Fungal_trans PF04082.13 OAJ29193.1 - 2.5e-21 75.7 0.0 1.3e-20 73.4 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ29193.1 - 3.6e-07 29.9 8.0 3.6e-07 29.9 5.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_4 PF08386.5 OAJ29194.1 - 4.1e-15 55.5 0.0 1.4e-14 53.8 0.0 1.9 1 1 1 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 OAJ29194.1 - 1.7e-13 50.6 0.0 4.1e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ29194.1 - 1.8e-09 37.8 0.0 5e-08 33.1 0.0 2.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ29194.1 - 2e-05 24.3 0.0 0.00029 20.6 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Dec-1 PF04624.9 OAJ29194.1 - 0.0085 15.6 2.3 1 9.0 0.3 2.3 2 0 0 2 2 2 2 Dec-1 repeat PAP2 PF01569.16 OAJ29195.1 - 4.2e-17 62.0 5.6 1.3e-16 60.4 3.9 1.8 1 0 0 1 1 1 1 PAP2 superfamily RecT PF03837.9 OAJ29195.1 - 0.19 11.0 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 RecT family Aminotran_5 PF00266.14 OAJ29196.1 - 1.2e-32 113.0 0.0 2.3e-31 108.9 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V LSM PF01423.17 OAJ29197.1 - 6.5e-16 57.6 0.0 8.1e-16 57.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Glypican PF01153.14 OAJ29198.1 - 2.4 6.6 4.5 6.8 5.1 3.1 1.8 1 0 0 1 1 1 0 Glypican API5 PF05918.6 OAJ29198.1 - 6.1 5.2 12.0 0.061 11.8 1.9 2.0 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Pkinase PF00069.20 OAJ29199.1 - 3.6e-70 236.0 0.0 4.5e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ29199.1 - 1.2e-29 103.2 0.0 1.6e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ29199.1 - 0.029 14.0 0.1 0.029 14.0 0.0 2.9 2 2 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 OAJ29199.1 - 0.92 8.5 4.0 0.47 9.4 0.1 2.3 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rootletin PF15035.1 OAJ29200.1 - 0.0029 17.5 11.3 0.0029 17.5 7.8 4.7 3 2 1 4 4 4 1 Ciliary rootlet component, centrosome cohesion DUF4200 PF13863.1 OAJ29200.1 - 0.008 16.1 9.0 0.008 16.1 6.3 4.6 4 1 0 4 4 4 1 Domain of unknown function (DUF4200) Myosin_tail_1 PF01576.14 OAJ29200.1 - 0.017 12.8 35.8 0.18 9.4 21.8 2.5 2 1 0 2 2 2 0 Myosin tail SseC PF04888.7 OAJ29200.1 - 1.2 8.4 0.0 1.2 8.4 0.0 3.5 5 0 0 5 5 5 0 Secretion system effector C (SseC) like family HALZ PF02183.13 OAJ29200.1 - 3.2 7.5 16.4 0.43 10.3 0.4 4.7 3 1 1 4 4 4 0 Homeobox associated leucine zipper RNA_pol_Rpc34 PF05158.7 OAJ29201.1 - 2.3e-79 266.9 1.8 1.1e-68 231.8 0.1 2.5 2 1 0 2 2 2 2 RNA polymerase Rpc34 subunit HTH_36 PF13730.1 OAJ29201.1 - 0.023 14.7 0.0 0.069 13.2 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.14 OAJ29201.1 - 0.06 13.0 0.0 0.55 9.9 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.1 OAJ29201.1 - 0.09 12.6 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix U1snRNP70_N PF12220.3 OAJ29202.1 - 8.2e-11 42.0 21.7 6.9e-09 35.9 15.0 2.4 1 1 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PITH PF06201.8 OAJ29203.1 - 6.4e-19 68.2 0.0 1.2e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 PITH domain Ribonuclease_3 PF00636.21 OAJ29205.1 - 5.6e-26 91.2 0.0 2.2e-12 47.4 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 OAJ29205.1 - 1.2e-15 57.6 0.1 9.2e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease-III-like tRNA-synt_1 PF00133.17 OAJ29206.1 - 1e-88 297.8 0.0 2.1e-82 277.0 0.0 2.0 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) PUB PF09409.5 OAJ29206.1 - 0.058 13.1 0.7 0.11 12.2 0.5 1.5 1 0 0 1 1 1 0 PUB domain tRNA-synt_1 PF00133.17 OAJ29207.1 - 1.9e-18 65.8 0.1 2.2e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) WD40 PF00400.27 OAJ29211.1 - 1.1e-15 56.7 0.1 5.3e-07 29.2 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat SAM_MT PF04445.8 OAJ29212.1 - 0.15 11.1 0.1 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Asp PF00026.18 OAJ29213.1 - 5.9e-33 114.4 5.8 5e-18 65.4 2.9 2.5 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ29213.1 - 5.9e-06 26.3 1.8 6.1e-05 23.0 1.3 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal DUF390 PF04094.9 OAJ29214.1 - 0.035 12.1 3.0 0.043 11.8 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) YbgS PF13985.1 OAJ29215.1 - 0.04 13.8 0.1 0.055 13.3 0.1 1.1 1 0 0 1 1 1 0 YbgS-like protein PBP PF01161.15 OAJ29216.1 - 9.2e-22 77.4 0.2 1.7e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein WD40 PF00400.27 OAJ29217.1 - 5.8e-75 244.7 15.1 6.6e-14 51.1 0.1 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 OAJ29217.1 - 2.5e-10 39.1 17.1 0.0045 15.1 0.2 5.5 2 1 3 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAJ29217.1 - 7.2e-05 21.7 1.9 2 7.0 0.0 4.2 1 1 3 5 5 5 4 Nup133 N terminal like eIF2A PF08662.6 OAJ29217.1 - 0.013 15.2 0.0 3.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 OAJ29217.1 - 0.031 12.5 0.2 2 6.6 0.0 2.3 2 1 0 2 2 2 0 Cytochrome D1 heme domain DUF1652 PF07865.6 OAJ29217.1 - 0.073 12.6 0.0 19 4.9 0.0 4.1 6 0 0 6 6 6 0 Protein of unknown function (DUF1652) Enolase_C PF00113.17 OAJ29218.1 - 1e-143 477.7 0.2 1.3e-143 477.3 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 OAJ29218.1 - 9.4e-57 190.6 0.2 1.7e-56 189.7 0.1 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 OAJ29218.1 - 6.2e-05 22.9 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 OAJ29218.1 - 0.0074 15.2 0.1 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 OAJ29218.1 - 0.06 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain APC10 PF03256.11 OAJ29219.1 - 3.1e-42 144.3 0.7 4.8e-42 143.7 0.0 1.7 2 1 0 2 2 2 1 Anaphase-promoting complex, subunit 10 (APC10) Chitin_synth_2 PF03142.10 OAJ29220.1 - 7.4e-239 793.5 0.1 7.4e-239 793.5 0.1 1.6 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.16 OAJ29220.1 - 4.5e-150 500.9 0.0 7.2e-150 500.2 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 OAJ29220.1 - 4.5e-18 65.6 0.9 1.2e-17 64.2 0.2 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 OAJ29220.1 - 6.8e-15 54.6 0.0 8.9e-07 28.6 0.0 2.9 2 1 1 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 OAJ29220.1 - 1.6e-13 50.9 0.0 6.5e-10 39.2 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DEK_C PF08766.6 OAJ29220.1 - 1.7e-13 50.1 1.6 4.4e-12 45.5 0.0 3.4 4 0 0 4 4 4 1 DEK C terminal domain Glycos_transf_2 PF00535.21 OAJ29220.1 - 0.00013 21.6 0.0 0.014 15.1 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 OAJ29220.1 - 0.028 13.6 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 21 AAA_16 PF13191.1 OAJ29220.1 - 0.06 13.3 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 OAJ29220.1 - 0.15 11.1 0.0 0.38 9.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 OAJ29220.1 - 0.17 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Lyase_aromatic PF00221.14 OAJ29221.1 - 8.6e-09 34.3 0.7 1.6e-06 26.9 0.3 2.7 2 1 0 2 2 2 2 Aromatic amino acid lyase IncA PF04156.9 OAJ29222.1 - 0.057 13.0 1.2 0.08 12.5 0.9 1.3 1 0 0 1 1 1 0 IncA protein FlxA PF14282.1 OAJ29222.1 - 0.11 12.4 8.8 0.15 11.9 6.1 1.1 1 0 0 1 1 1 0 FlxA-like protein DASH_Spc34 PF08657.5 OAJ29222.1 - 0.11 12.1 3.0 0.14 11.8 2.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 M_domain PF12938.2 OAJ29222.1 - 0.16 11.7 3.7 0.23 11.2 2.5 1.1 1 0 0 1 1 1 0 M domain of GW182 YlqD PF11068.3 OAJ29222.1 - 0.68 9.9 4.1 0.86 9.6 2.8 1.1 1 0 0 1 1 1 0 YlqD protein Ricin_B_lectin PF00652.17 OAJ29224.1 - 0.068 13.1 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain 2OG-FeII_Oxy_3 PF13640.1 OAJ29227.1 - 0.00029 21.2 0.3 0.00083 19.8 0.2 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ29227.1 - 0.016 15.4 0.1 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Clostridium_P47 PF06597.6 OAJ29227.1 - 0.058 11.9 0.0 0.092 11.2 0.0 1.2 1 0 0 1 1 1 0 Clostridium P-47 protein LAT PF15234.1 OAJ29228.1 - 0.068 12.6 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells DUF4017 PF13209.1 OAJ29228.1 - 0.1 12.4 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) HA2 PF04408.18 OAJ29229.1 - 6.9e-15 54.9 0.0 2.3e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ29229.1 - 7.2e-14 51.4 0.1 1.5e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ29229.1 - 1.1e-09 38.0 0.0 4.3e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ29229.1 - 9.5e-05 22.5 0.0 0.00031 20.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 OAJ29229.1 - 0.048 12.7 0.1 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 KaiC ResIII PF04851.10 OAJ29229.1 - 0.33 10.7 0.0 0.76 9.5 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_membrane PF00664.18 OAJ29230.1 - 3.5e-95 318.5 24.8 6.1e-50 170.1 9.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ29230.1 - 1.6e-68 229.2 0.0 2.7e-33 115.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAJ29230.1 - 8.5e-17 61.1 1.3 9.8e-05 21.6 0.0 4.4 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAJ29230.1 - 5.4e-14 52.8 0.0 0.021 14.7 0.0 4.3 3 1 0 4 4 4 4 AAA domain ABC_ATPase PF09818.4 OAJ29230.1 - 5.5e-14 51.5 1.5 0.00027 19.6 0.1 4.2 4 0 0 4 4 4 3 Predicted ATPase of the ABC class AAA_29 PF13555.1 OAJ29230.1 - 1.6e-08 33.9 1.0 0.00033 20.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 OAJ29230.1 - 3.8e-07 30.9 0.0 0.036 14.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAJ29230.1 - 1.2e-06 28.6 0.4 0.16 12.1 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAJ29230.1 - 1.9e-06 27.9 6.7 0.011 15.6 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain DUF258 PF03193.11 OAJ29230.1 - 2.2e-06 26.9 0.0 0.071 12.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 OAJ29230.1 - 5.6e-06 25.8 0.1 0.051 12.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 OAJ29230.1 - 1e-05 25.9 0.3 0.23 11.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 OAJ29230.1 - 1.1e-05 25.2 2.0 0.13 12.1 0.2 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 OAJ29230.1 - 6e-05 22.7 0.3 0.36 10.3 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 OAJ29230.1 - 0.00022 21.5 0.0 0.69 10.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 OAJ29230.1 - 0.00035 20.4 0.0 2.3 8.1 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_5 PF07728.9 OAJ29230.1 - 0.00067 19.3 0.1 2.9 7.6 0.0 3.9 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) DUF87 PF01935.12 OAJ29230.1 - 0.001 18.9 0.2 2 8.1 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_33 PF13671.1 OAJ29230.1 - 0.0027 17.6 0.3 1.1 9.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain PRK PF00485.13 OAJ29230.1 - 0.0087 15.6 0.0 1.5 8.3 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 OAJ29230.1 - 0.01 15.8 0.5 4.7 7.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.1 OAJ29230.1 - 0.011 14.7 0.0 1.3 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 OAJ29230.1 - 0.022 14.2 0.5 2.3 7.6 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 OAJ29230.1 - 0.023 14.1 0.7 6.8 6.0 0.0 3.3 4 0 0 4 4 4 0 AAA-like domain Miro PF08477.8 OAJ29230.1 - 0.024 15.1 0.0 5.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 OAJ29230.1 - 0.024 14.7 0.0 6.1 7.0 0.0 3.3 3 0 0 3 3 2 0 RNA helicase Viral_helicase1 PF01443.13 OAJ29230.1 - 0.035 13.6 0.0 2.1 7.8 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.15 OAJ29230.1 - 0.036 13.7 0.1 0.76 9.4 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF815 PF05673.8 OAJ29230.1 - 0.04 12.8 0.0 7.9 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MobB PF03205.9 OAJ29230.1 - 0.045 13.4 0.1 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 OAJ29230.1 - 0.087 11.6 0.1 12 4.6 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.10 OAJ29230.1 - 0.13 10.9 0.0 1.1 7.7 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein IMS PF00817.15 OAJ29231.1 - 3.8e-39 133.8 0.0 9.8e-39 132.5 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 OAJ29231.1 - 2.2e-14 53.4 0.0 5.7e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 OAJ29231.1 - 6.5e-07 29.2 0.1 0.028 14.3 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) ABC_membrane_3 PF13748.1 OAJ29232.1 - 0.07 12.1 0.6 0.14 11.1 0.4 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region Thioredoxin PF00085.15 OAJ29233.1 - 3.5e-27 94.1 0.0 8.6e-26 89.6 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 OAJ29233.1 - 5.2e-05 23.2 0.0 0.00018 21.5 0.0 1.9 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ29233.1 - 0.00025 21.2 0.0 0.0012 19.0 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 OAJ29233.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.5 OAJ29233.1 - 0.011 15.3 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.16 OAJ29233.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Mog1 PF04603.7 OAJ29234.1 - 3.5e-31 108.0 0.1 7.3e-31 106.9 0.0 1.5 1 1 0 1 1 1 1 Ran-interacting Mog1 protein IMPDH PF00478.20 OAJ29235.1 - 6.3e-137 456.1 0.0 3e-135 450.6 0.0 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 OAJ29235.1 - 2.8e-20 71.8 0.0 1.5e-09 37.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 OAJ29235.1 - 1.1e-10 41.1 11.9 2e-07 30.4 7.2 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 OAJ29235.1 - 1.3e-08 34.0 4.1 3.7e-08 32.6 2.8 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 OAJ29235.1 - 8.2e-08 31.7 2.8 8.2e-07 28.5 2.0 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 OAJ29235.1 - 1.1e-05 24.6 1.6 1.8e-05 23.9 1.1 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Dus PF01207.12 OAJ29235.1 - 0.14 11.0 0.6 0.62 8.8 0.0 2.0 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DUF1767 PF08585.7 OAJ29236.1 - 3.6e-13 49.5 0.0 6.3e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) DUF619 PF04768.8 OAJ29238.1 - 4.6e-43 146.5 0.0 7.7e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) AA_kinase PF00696.23 OAJ29238.1 - 1.9e-22 80.0 0.0 3.9e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.19 OAJ29238.1 - 3.2e-22 79.0 0.0 7.3e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 OAJ29238.1 - 0.012 16.1 0.0 0.15 12.5 0.0 2.9 3 1 1 4 4 4 0 Oxidoreductase family, NAD-binding Rossmann fold Arm PF00514.18 OAJ29238.1 - 0.036 13.9 0.2 0.41 10.5 0.0 2.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DapB_N PF01113.15 OAJ29238.1 - 0.072 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF1917 PF08939.5 OAJ29239.1 - 2.7e-11 43.7 1.6 2.7e-11 43.7 1.1 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF1917) Serglycin PF04360.7 OAJ29239.1 - 0.65 9.7 5.5 1.6 8.4 3.8 1.8 1 1 0 1 1 1 0 Serglycin Acetyltransf_8 PF13523.1 OAJ29240.1 - 4.6e-39 133.7 0.1 6.3e-39 133.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 OAJ29240.1 - 0.077 13.1 0.1 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Rcd1 PF04078.8 OAJ29241.1 - 2e-125 416.9 1.3 2.6e-125 416.5 0.9 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Cupin_8 PF13621.1 OAJ29242.1 - 0.0004 19.9 0.0 0.00046 19.7 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 OAJ29242.1 - 0.00053 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.6 OAJ29242.1 - 0.0007 19.0 0.2 0.23 10.9 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 OAJ29242.1 - 0.0019 17.6 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 OAJ29242.1 - 0.046 13.3 0.3 0.49 9.9 0.0 2.2 2 1 1 3 3 3 0 Cupin AraC_binding PF02311.14 OAJ29242.1 - 0.11 12.2 0.6 0.3 10.7 0.4 1.8 1 1 0 1 1 1 0 AraC-like ligand binding domain PepSY_2 PF13670.1 OAJ29242.1 - 0.12 12.2 0.2 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain FdtA PF05523.6 OAJ29242.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 WxcM-like, C-terminal Peptidase_M1 PF01433.15 OAJ29243.1 - 4.3e-67 226.8 0.3 7.5e-40 137.2 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M1 Cyclin_N PF00134.18 OAJ29244.1 - 9.7e-09 34.8 0.0 1.9e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 OAJ29244.1 - 0.0086 15.8 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C PF02984.14 OAJ29244.1 - 0.072 13.0 0.6 12 5.8 0.0 2.7 2 1 0 2 2 2 0 Cyclin, C-terminal domain HABP4_PAI-RBP1 PF04774.10 OAJ29245.1 - 1.1e-05 25.8 2.9 1.1e-05 25.8 2.0 3.6 3 1 1 4 4 4 1 Hyaluronan / mRNA binding family Methyltransf_33 PF10017.4 OAJ29246.1 - 6.1e-27 94.0 0.0 1.7e-26 92.5 0.0 1.8 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 OAJ29246.1 - 2.1e-17 63.3 1.7 3.7e-17 62.5 0.1 2.0 2 0 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 OAJ29246.1 - 1e-05 25.8 2.6 2e-05 24.9 0.9 2.3 2 0 0 2 2 2 1 DinB superfamily Ribosomal_S9 PF00380.14 OAJ29247.1 - 2e-39 134.5 0.4 2.3e-39 134.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_S3_C PF00189.15 OAJ29248.1 - 1.3e-16 60.5 0.1 2.3e-16 59.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 OAJ29248.1 - 2.4e-09 36.5 0.0 4.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 KH domain tRNA_int_end_N2 PF12928.2 OAJ29249.1 - 2.2e-09 36.6 0.0 5.1e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 OAJ29249.1 - 0.0004 19.8 0.0 0.00084 18.8 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain TFIIF_alpha PF05793.7 OAJ29250.1 - 0.19 10.0 11.0 0.28 9.5 7.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 OAJ29250.1 - 0.21 10.0 8.7 0.31 9.4 6.0 1.2 1 0 0 1 1 1 0 Daxx Family PBP_sp32 PF07222.7 OAJ29250.1 - 0.29 10.2 3.1 0.57 9.3 2.2 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 NARP1 PF12569.3 OAJ29250.1 - 2.5 6.7 7.4 3.8 6.1 5.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MULE PF10551.4 OAJ29251.1 - 2.2e-08 34.1 0.0 4.6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Sigma70_ner PF04546.8 OAJ29251.1 - 0.04 13.5 2.5 0.079 12.5 1.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CIA30 PF08547.7 OAJ29252.1 - 3.5e-18 65.9 0.0 3.1e-09 36.8 0.0 2.2 1 1 1 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Pol_alpha_B_N PF08418.5 OAJ29252.1 - 2.1 7.7 6.1 0.36 10.3 1.3 1.8 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Glyco_hydro_92 PF07971.7 OAJ29253.1 - 1.3e-08 33.9 0.0 5.2e-05 22.0 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 Histone PF00125.19 OAJ29254.1 - 2.5e-28 97.9 0.6 4e-28 97.3 0.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ29254.1 - 1.3e-05 25.3 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 OAJ29254.1 - 0.043 13.0 0.0 0.043 13.0 0.0 1.3 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 OAJ29254.1 - 0.045 13.4 0.1 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CBFD_NFYB_HMF PF00808.18 OAJ29254.1 - 0.22 11.6 1.3 0.22 11.5 0.1 1.5 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.20 OAJ29255.1 - 1.4e-73 247.2 0.0 1.7e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ29255.1 - 2.3e-40 138.2 0.0 2.9e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ29255.1 - 1.6e-06 27.2 0.0 2.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ29255.1 - 7.1e-06 25.2 0.0 1.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 OAJ29255.1 - 3.9e-05 23.0 0.0 6.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 OAJ29255.1 - 0.00094 18.9 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 OAJ29255.1 - 0.039 13.0 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pox_ser-thr_kin PF05445.6 OAJ29255.1 - 0.11 11.3 0.1 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 OAJ29255.1 - 0.14 11.7 0.1 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC_membrane PF00664.18 OAJ29256.1 - 4.9e-78 262.3 20.4 4e-46 157.6 4.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ29256.1 - 2.3e-50 170.4 0.1 2.9e-31 108.5 0.1 3.0 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAJ29256.1 - 1.6e-06 27.5 0.4 0.012 14.8 0.0 3.8 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 OAJ29256.1 - 0.00026 20.9 0.2 0.3 11.0 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 OAJ29256.1 - 0.00029 20.8 5.4 0.024 14.6 0.4 2.9 2 1 1 3 3 3 2 AAA ATPase domain DUF87 PF01935.12 OAJ29256.1 - 0.0013 18.6 0.8 0.29 10.9 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF258 PF03193.11 OAJ29256.1 - 0.0025 17.0 0.2 1 8.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 OAJ29256.1 - 0.003 17.0 0.8 3.2 7.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 OAJ29256.1 - 0.0034 17.2 0.4 0.48 10.2 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.1 OAJ29256.1 - 0.0043 16.4 0.2 4 6.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 OAJ29256.1 - 0.0047 15.8 0.0 0.47 9.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 OAJ29256.1 - 0.01 15.4 1.0 0.95 9.0 0.1 2.9 3 1 0 3 3 2 0 AAA domain AAA_21 PF13304.1 OAJ29256.1 - 0.031 14.2 0.0 8.2 6.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 OAJ29256.1 - 0.038 14.4 2.5 5.4 7.5 0.1 3.2 4 0 0 4 4 2 0 Miro-like protein ABC_ATPase PF09818.4 OAJ29256.1 - 0.13 10.8 0.5 0.8 8.2 0.1 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NmrA PF05368.8 OAJ29257.1 - 1.9e-35 122.2 0.1 2.3e-35 121.9 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAJ29257.1 - 1.6e-14 54.3 0.1 3.3e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 OAJ29257.1 - 5.5e-05 23.1 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 OAJ29257.1 - 0.00035 19.3 0.0 0.00049 18.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 OAJ29257.1 - 0.0014 18.3 0.0 0.0025 17.4 0.0 1.5 1 1 0 1 1 1 1 KR domain RAB3GAP2_N PF14655.1 OAJ29258.1 - 4.4 6.2 10.7 0.7 8.8 1.5 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Suf PF05843.9 OAJ29258.1 - 6.5 6.3 14.3 0.31 10.7 3.0 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) UPF0560 PF10577.4 OAJ29258.1 - 7.1 4.7 20.8 2.2 6.4 7.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 EPL1 PF10513.4 OAJ29258.1 - 9.8 6.3 11.8 4.9 7.3 2.4 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like adh_short_C2 PF13561.1 OAJ29259.1 - 3.5e-28 98.9 0.0 4e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ29259.1 - 4.3e-24 85.3 0.1 5.7e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ29259.1 - 2.7e-09 36.9 0.0 3.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 OAJ29259.1 - 0.0026 16.9 0.0 0.0031 16.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Nop14 PF04147.7 OAJ29260.1 - 1.1 7.0 12.5 1.5 6.6 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 OAJ29260.1 - 3.4 6.6 12.6 6.1 5.8 8.7 1.4 1 0 0 1 1 1 0 BUD22 DUF1757 PF08560.5 OAJ29261.1 - 0.037 13.7 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) TctB PF07331.6 OAJ29261.1 - 0.13 11.8 2.7 0.22 11.1 0.4 2.1 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DIM PF08194.7 OAJ29262.1 - 0.025 14.5 0.4 0.041 13.8 0.3 1.4 1 0 0 1 1 1 0 DIM protein WD40 PF00400.27 OAJ29263.1 - 2.5e-38 128.6 19.2 6.8e-08 32.1 0.4 7.0 8 0 0 8 8 8 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 OAJ29263.1 - 0.044 12.5 1.0 12 4.4 0.0 3.2 2 1 1 3 3 3 0 Nup133 N terminal like Pro_isomerase PF00160.16 OAJ29264.1 - 3.4e-16 59.8 0.0 4.5e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_C50 PF03568.12 OAJ29264.1 - 0.21 10.2 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C50 eIF-5_eIF-2B PF01873.12 OAJ29265.1 - 3.4e-41 139.7 0.1 5.3e-41 139.1 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 OAJ29265.1 - 1.8e-22 79.0 0.4 1.2e-21 76.4 0.1 2.5 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon DUF974 PF06159.8 OAJ29266.1 - 4.6e-38 131.0 0.0 1.3e-30 106.6 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF974) Transglut_C PF00927.17 OAJ29266.1 - 0.023 14.7 0.0 0.082 12.9 0.0 1.8 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain Med26 PF08711.6 OAJ29267.1 - 7.1e-10 38.2 0.0 1.6e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain PH PF00169.24 OAJ29268.1 - 3.3e-39 133.2 1.3 2.6e-19 69.3 0.2 3.3 3 0 0 3 3 3 3 PH domain PH_11 PF15413.1 OAJ29268.1 - 4.6e-18 65.5 8.9 1.7e-07 31.4 3.5 4.3 3 1 0 3 3 3 3 Pleckstrin homology domain PH_3 PF14593.1 OAJ29268.1 - 4.4e-16 58.6 2.2 1e-07 31.8 0.3 3.2 3 0 0 3 3 3 3 PH domain PH_8 PF15409.1 OAJ29268.1 - 1.5e-11 44.1 5.0 3.7e-07 30.1 0.9 3.0 3 0 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.1 OAJ29268.1 - 7.7e-07 29.2 7.8 0.00071 19.7 0.8 4.3 3 1 0 3 3 3 2 Pleckstrin homology domain Mcp5_PH PF12814.2 OAJ29268.1 - 1.1e-05 25.3 3.2 0.16 11.9 0.6 3.5 3 0 0 3 3 3 2 Meiotic cell cortex C-terminal pleckstrin homology PH_7 PF15408.1 OAJ29268.1 - 7.7e-05 22.5 0.9 0.00035 20.4 0.1 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.1 OAJ29268.1 - 1.5 8.3 16.1 0.17 11.3 0.2 4.5 3 1 2 5 5 5 0 Pleckstrin homology domain Cupin_8 PF13621.1 OAJ29269.1 - 4e-18 65.8 0.0 7.7e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 OAJ29269.1 - 1.2e-17 64.2 0.1 1.1e-16 61.1 0.1 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase GPI PF06560.6 OAJ29269.1 - 0.02 13.8 0.0 0.043 12.8 0.0 1.5 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) NUDIX PF00293.23 OAJ29270.1 - 2.1e-10 40.3 0.0 3.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DNA_pol_viral_C PF00336.13 OAJ29273.1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain RVT_3 PF13456.1 OAJ29273.1 - 0.084 12.6 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like zf-CCHC_4 PF14392.1 OAJ29273.1 - 0.37 10.5 5.6 0.092 12.4 0.9 2.1 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.20 OAJ29274.1 - 1.4e-22 80.1 0.0 2.7e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ29274.1 - 5.2e-13 48.6 0.0 1.3e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ29274.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF1880 PF08976.6 OAJ29274.1 - 0.61 10.2 3.9 1.9 8.6 2.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1880) Peptidase_S9 PF00326.16 OAJ29275.1 - 2.1e-32 112.0 0.0 6e-32 110.6 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 OAJ29275.1 - 4.6e-12 46.3 0.1 9.3e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ29275.1 - 8.9e-11 41.7 0.0 2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 OAJ29275.1 - 5.2e-05 23.0 0.0 0.00013 21.6 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 OAJ29275.1 - 0.00036 19.8 0.0 0.0026 17.0 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.7 OAJ29275.1 - 0.0014 17.1 0.0 0.0021 16.6 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 OAJ29275.1 - 0.0051 16.4 0.1 0.036 13.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 OAJ29275.1 - 0.055 12.8 0.0 2.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2439 PF10382.4 OAJ29276.1 - 7e-09 35.7 0.1 1.1e-08 35.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) FKBP_C PF00254.23 OAJ29277.1 - 4.1e-27 94.0 0.0 8.7e-27 92.9 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2457 PF10446.4 OAJ29277.1 - 0.0064 15.2 16.0 0.0064 15.2 11.1 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 OAJ29277.1 - 0.013 15.7 10.4 0.013 15.7 7.2 4.2 4 1 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Daxx PF03344.10 OAJ29277.1 - 0.7 8.3 34.9 0.42 9.0 12.4 2.1 2 0 0 2 2 2 0 Daxx Family DUF812 PF05667.6 OAJ29277.1 - 2.8 6.3 11.8 3.8 5.9 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Macoilin PF09726.4 OAJ29277.1 - 3.8 5.6 12.0 5.3 5.2 8.3 1.1 1 0 0 1 1 1 0 Transmembrane protein KH_1 PF00013.24 OAJ29278.1 - 1.2e-82 271.4 33.9 1.5e-12 46.9 0.1 13.7 13 1 0 13 13 13 11 KH domain KH_3 PF13014.1 OAJ29278.1 - 9.5e-61 200.6 21.9 3.8e-08 32.7 0.0 11.8 11 0 0 11 11 11 10 KH domain KH_2 PF07650.12 OAJ29278.1 - 7.7e-11 41.4 27.4 0.3 10.6 0.3 9.4 9 1 1 10 10 10 6 KH domain KH_4 PF13083.1 OAJ29278.1 - 0.00013 21.5 22.5 0.056 13.0 0.1 8.8 7 1 2 9 9 9 3 KH domain DDE_3 PF13358.1 OAJ29279.1 - 1.5e-20 73.4 0.0 2.4e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 OAJ29279.1 - 3.9e-09 36.4 3.2 3.9e-09 36.4 2.2 3.2 4 0 0 4 4 4 1 Transposase HTH_Tnp_ISL3 PF13542.1 OAJ29279.1 - 4.1e-08 32.2 2.5 3.4e-05 22.9 0.0 3.7 4 0 0 4 4 4 2 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.1 OAJ29279.1 - 1.8e-06 27.4 0.6 7e-06 25.5 0.0 2.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.1 OAJ29279.1 - 6.8e-06 25.5 0.0 1.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 OAJ29279.1 - 0.00011 22.3 0.4 0.044 14.0 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain CENP-B_N PF04218.8 OAJ29279.1 - 0.00029 20.1 0.0 0.00067 19.0 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain GerE PF00196.14 OAJ29279.1 - 0.00065 18.9 0.1 0.0025 17.0 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_28 PF13518.1 OAJ29279.1 - 0.0023 17.9 0.0 0.0082 16.1 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain DUF2857 PF11198.3 OAJ29279.1 - 0.015 14.8 0.1 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) Sigma70_r4_2 PF08281.7 OAJ29279.1 - 0.032 13.6 0.3 0.18 11.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 rve PF00665.21 OAJ29279.1 - 0.045 13.8 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain HTH_7 PF02796.10 OAJ29279.1 - 0.091 12.6 0.5 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_3 PF01381.17 OAJ29279.1 - 0.092 12.6 0.3 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix LacI PF00356.16 OAJ29279.1 - 0.11 12.1 0.6 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_31 PF13560.1 OAJ29279.1 - 0.32 11.2 2.2 0.49 10.6 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain BRO1 PF03097.13 OAJ29280.1 - 3.5e-17 62.2 0.0 1.2e-13 50.5 0.0 2.0 2 0 0 2 2 2 2 BRO1-like domain DPBB_1 PF03330.13 OAJ29282.1 - 1.4e-09 37.8 0.1 2.9e-09 36.8 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ29282.1 - 0.087 12.5 0.5 0.16 11.6 0.4 1.5 1 1 0 1 1 1 0 Barwin family Redoxin PF08534.5 OAJ29283.1 - 1.1e-07 31.5 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAJ29283.1 - 9.4e-06 25.3 0.0 8.9e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family Phage_integrase PF00589.17 OAJ29285.1 - 0.00057 19.5 0.0 0.00075 19.2 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family MULE PF10551.4 OAJ29287.1 - 3.2e-19 68.9 0.0 6.8e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ29287.1 - 2.7e-10 39.3 0.0 3.6e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Paf1 PF03985.8 OAJ29288.1 - 0.022 13.5 6.2 0.027 13.2 4.3 1.2 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.7 OAJ29288.1 - 0.098 12.5 4.5 0.1 12.4 3.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spt5_N PF11942.3 OAJ29288.1 - 0.12 12.9 11.7 0.21 12.2 8.1 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.9 OAJ29288.1 - 0.48 8.4 7.7 0.6 8.0 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2072 PF09845.4 OAJ29288.1 - 1.2 9.0 6.7 1.2 9.1 3.7 1.6 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) DUF3381 PF11861.3 OAJ29288.1 - 2.3 7.7 10.5 4 6.9 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Herpes_DNAp_acc PF04929.7 OAJ29288.1 - 2.6 6.9 6.2 3 6.6 4.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor zf-CHY PF05495.7 OAJ29289.1 - 1.7e-14 53.7 14.0 2.5e-14 53.1 9.7 1.2 1 0 0 1 1 1 1 CHY zinc finger Zn-ribbon_8 PF09723.5 OAJ29289.1 - 0.046 13.6 10.0 0.052 13.5 1.3 2.6 2 0 0 2 2 2 0 Zinc ribbon domain MoCo_carrier PF12694.2 OAJ29289.1 - 0.095 12.1 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Putative molybdenum carrier Evr1_Alr PF04777.8 OAJ29289.1 - 0.29 11.0 4.5 0.62 9.9 3.0 1.7 1 1 0 1 1 1 0 Erv1 / Alr family Elf1 PF05129.8 OAJ29289.1 - 0.71 9.5 9.2 0.11 12.1 3.3 1.8 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-HYPF PF07503.7 OAJ29289.1 - 1.1 8.7 6.8 0.12 11.8 0.9 2.1 2 0 0 2 2 2 0 HypF finger DZR PF12773.2 OAJ29289.1 - 1.2 9.0 9.3 0.72 9.7 4.5 2.1 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 OAJ29289.1 - 2.3 7.9 8.9 0.22 11.2 1.1 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family C1_4 PF07975.7 OAJ29289.1 - 2.7 8.0 9.2 4.2 7.4 5.0 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 OAJ29289.1 - 3.3 7.5 10.4 28 4.6 5.5 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 OAJ29289.1 - 8.7 6.0 13.0 55 3.4 5.1 3.4 2 1 0 2 2 2 0 zinc-ribbon domain Sugar_tr PF00083.19 OAJ29290.1 - 2.9e-86 289.8 19.1 4.6e-71 239.7 3.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ29290.1 - 7.2e-22 77.5 15.6 7.2e-22 77.5 10.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily COX16 PF14138.1 OAJ29291.1 - 1.1e-24 86.3 0.1 2e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Evr1_Alr PF04777.8 OAJ29291.1 - 4.3e-24 84.2 0.0 1.3e-23 82.7 0.0 1.8 2 0 0 2 2 2 1 Erv1 / Alr family KH_1 PF00013.24 OAJ29292.1 - 1.3e-42 143.1 9.0 4e-16 58.3 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 OAJ29292.1 - 5e-31 105.7 15.0 2.5e-10 39.7 1.4 3.8 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 OAJ29292.1 - 4.8e-15 54.8 7.0 2.5e-05 23.7 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 OAJ29292.1 - 3.3e-06 26.6 1.8 0.64 9.7 0.0 3.4 3 0 0 3 3 3 3 KH domain CEP170_C PF15308.1 OAJ29292.1 - 0.0085 14.4 13.7 0.011 14.0 9.5 1.1 1 0 0 1 1 1 1 CEP170 C-terminus KH_5 PF13184.1 OAJ29292.1 - 0.01 15.5 5.0 1.5 8.6 0.1 3.5 3 0 0 3 3 3 0 NusA-like KH domain Sugar_tr PF00083.19 OAJ29294.1 - 2.4e-120 402.1 23.3 2.8e-120 401.9 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ29294.1 - 2.3e-21 75.9 41.2 2.8e-20 72.3 8.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RVT_2 PF07727.9 OAJ29295.1 - 2.2e-85 285.5 0.0 2.9e-85 285.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ29295.1 - 8.9e-25 87.1 0.1 2.3e-24 85.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ29295.1 - 3.6e-06 26.5 0.0 3.6e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ29295.1 - 0.00027 20.3 0.0 0.00062 19.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Transcript_VP30 PF11507.3 OAJ29295.1 - 0.039 13.7 0.2 0.077 12.8 0.1 1.4 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 RVT_1 PF00078.22 OAJ29295.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_E_B PF04042.11 OAJ29297.1 - 1.3e-40 138.9 0.0 2.9e-40 137.7 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Mito_carr PF00153.22 OAJ29298.1 - 2.5e-38 129.6 2.3 3.6e-14 52.2 0.1 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein Fungal_trans PF04082.13 OAJ29299.1 - 6.2e-16 58.0 4.2 1e-15 57.3 2.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ29299.1 - 0.00011 21.9 7.7 0.00021 21.1 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Daxx PF03344.10 OAJ29299.1 - 0.00093 17.8 6.3 0.00093 17.8 4.4 1.7 2 0 0 2 2 2 1 Daxx Family CENP-B_dimeris PF09026.5 OAJ29299.1 - 0.44 10.8 19.4 1.2 9.3 11.4 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Borrelia_P83 PF05262.6 OAJ29302.1 - 0.15 10.3 9.8 0.21 9.8 6.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein NARP1 PF12569.3 OAJ29302.1 - 0.27 9.9 11.9 0.37 9.4 8.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.7 OAJ29302.1 - 3.7 7.3 9.4 7 6.4 6.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDRGK PF09756.4 OAJ29302.1 - 4.5 6.6 14.4 6.8 6.0 10.0 1.2 1 0 0 1 1 1 0 DDRGK domain DUF4407 PF14362.1 OAJ29302.1 - 4.9 6.0 10.4 7.7 5.3 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2413 PF10310.4 OAJ29302.1 - 6.4 5.4 14.8 10 4.8 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Dynamin_M PF01031.15 OAJ29304.1 - 1.5e-113 378.4 0.0 2.3e-113 377.8 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 OAJ29304.1 - 8.9e-56 188.3 0.0 1.6e-55 187.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 OAJ29304.1 - 3.3e-28 97.4 0.2 2.3e-27 94.6 0.1 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 OAJ29304.1 - 0.0021 18.0 0.0 0.0064 16.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAJ29304.1 - 0.042 14.3 0.0 0.09 13.2 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Surp PF01805.15 OAJ29306.1 - 1.8e-12 46.7 0.3 3.9e-12 45.6 0.2 1.5 1 0 0 1 1 1 1 Surp module RRM_6 PF14259.1 OAJ29306.1 - 2.3e-06 27.5 0.0 5.3e-05 23.1 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ29306.1 - 1.7e-05 24.3 0.0 0.17 11.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTK3 PF12243.3 OAJ29306.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 RRM_5 PF13893.1 OAJ29306.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GatB_N PF02934.10 OAJ29307.1 - 3.6e-84 282.0 0.0 1.4e-83 280.1 0.0 1.9 1 1 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 OAJ29307.1 - 3.5e-26 91.7 0.0 1.3e-14 54.1 0.0 2.4 2 0 0 2 2 2 2 GatB domain ADH_zinc_N PF00107.21 OAJ29308.1 - 2.5e-28 98.1 0.3 5.5e-28 97.1 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ29308.1 - 7.7e-13 49.4 0.7 1.8e-12 48.2 0.0 2.0 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ29308.1 - 2.8e-09 36.7 0.0 4e-08 32.9 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain UvrD_C PF13361.1 OAJ29309.1 - 1.9e-15 57.2 0.1 5e-15 55.8 0.1 1.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 OAJ29309.1 - 7.6e-11 41.8 0.7 7.6e-11 41.8 0.5 3.2 4 1 0 4 4 4 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 OAJ29309.1 - 3.6e-09 36.7 0.0 1.1e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 OAJ29309.1 - 1.5e-07 31.2 0.0 0.0011 18.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 OAJ29309.1 - 1.8e-07 30.9 0.1 0.084 12.3 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 OAJ29309.1 - 0.0021 17.7 0.0 0.0064 16.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 OAJ29309.1 - 0.011 15.8 1.1 12 6.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain Mito_carr PF00153.22 OAJ29311.1 - 2.3e-48 161.8 4.6 3.5e-17 61.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PMSR PF01625.16 OAJ29312.1 - 1.4e-54 184.1 0.3 1.7e-54 183.9 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase 2-Hacid_dh_C PF02826.14 OAJ29313.1 - 8.5e-37 126.0 0.0 6.3e-36 123.1 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 OAJ29313.1 - 8.9e-05 22.6 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh PF00389.25 OAJ29313.1 - 0.0064 15.9 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain PA_decarbox PF05870.6 OAJ29314.1 - 4.3e-26 91.3 0.7 4.9e-26 91.1 0.5 1.0 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) MoaF PF10703.4 OAJ29314.1 - 7.5e-06 25.2 0.4 1e-05 24.7 0.3 1.2 1 0 0 1 1 1 1 Molybdenum cofactor biosynthesis protein F Glyco_hydro_20 PF00728.17 OAJ29315.1 - 1.3e-78 264.6 0.0 1.6e-78 264.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 OAJ29315.1 - 4.5e-15 56.4 0.0 7.5e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 OAJ29315.1 - 0.0015 19.0 0.4 0.02 15.3 0.3 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Rhomboid PF01694.17 OAJ29316.1 - 7.3e-09 35.7 13.7 0.00023 21.2 0.2 2.8 2 1 0 2 2 2 2 Rhomboid family zf-C2H2_jaz PF12171.3 OAJ29317.1 - 2.5e-07 30.6 0.1 3.8e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAJ29317.1 - 4.5e-05 23.4 0.2 7.1e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 OAJ29317.1 - 0.00021 20.9 0.0 0.00043 19.8 0.0 1.5 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2 PF00096.21 OAJ29317.1 - 0.16 12.4 0.7 0.28 11.6 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type CAF-1_p150 PF11600.3 OAJ29317.1 - 0.54 9.5 25.9 0.09 12.1 8.7 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PIG-L PF02585.12 OAJ29318.1 - 2.2e-24 86.3 0.6 5.5e-24 85.0 0.4 1.7 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase SDA1 PF05285.7 OAJ29319.1 - 0.084 12.1 6.9 0.12 11.6 4.8 1.1 1 0 0 1 1 1 0 SDA1 Spt5_N PF11942.3 OAJ29319.1 - 2.2 8.9 15.5 4.6 7.9 1.4 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RXT2_N PF08595.6 OAJ29319.1 - 3.6 7.3 8.8 12 5.6 5.7 1.9 1 1 1 2 2 2 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 OAJ29319.1 - 3.8 7.0 10.7 5.4 6.5 2.4 2.3 2 0 0 2 2 2 0 Nucleoplasmin tRNA-synt_1 PF00133.17 OAJ29320.1 - 4.1e-69 233.1 0.1 4.6e-69 232.9 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 OAJ29320.1 - 1.1e-08 34.1 0.5 6e-07 28.4 0.3 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) Phosducin PF02114.11 OAJ29321.1 - 6.5e-15 54.5 0.2 6.8e-07 28.2 0.0 3.3 3 0 0 3 3 3 3 Phosducin FAM176 PF14851.1 OAJ29321.1 - 3 7.5 10.9 2.8 7.6 1.4 3.2 3 0 0 3 3 3 0 FAM176 family ABC2_membrane PF01061.19 OAJ29322.1 - 0.0011 18.1 0.3 0.0011 18.1 0.2 1.7 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.7 OAJ29322.1 - 0.16 11.6 0.3 0.23 11.1 0.2 1.4 1 1 0 1 1 1 0 CDR ABC transporter Ndc1_Nup PF09531.5 OAJ29324.1 - 1.5e-09 36.8 17.1 1.4e-08 33.6 0.0 4.9 4 2 1 5 5 5 3 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.11 OAJ29325.1 - 3.1e-43 147.8 58.0 9.2e-43 146.2 35.5 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAJ29325.1 - 7e-18 64.1 13.4 7e-18 64.1 9.3 1.9 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 OAJ29325.1 - 3.9e-15 55.3 5.0 3.9e-15 55.3 3.5 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter SurE PF01975.12 OAJ29327.1 - 2.2e-14 53.2 2.3 2.8e-14 52.8 0.0 1.9 1 1 1 2 2 2 1 Survival protein SurE ABC1 PF03109.11 OAJ29328.1 - 3.8e-22 78.4 0.0 3.8e-14 52.6 0.0 2.4 2 0 0 2 2 2 2 ABC1 family MFS_1 PF07690.11 OAJ29329.1 - 4.9e-33 114.3 37.4 7.9e-33 113.6 25.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 OAJ29329.1 - 0.0071 14.4 1.0 0.016 13.2 0.7 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_32N PF00251.15 OAJ29330.1 - 4.2e-23 82.1 0.0 9.6e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 OAJ29330.1 - 2.9e-05 24.3 0.0 5.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 OAJ29330.1 - 0.073 12.9 1.7 0.48 10.4 0.0 3.2 2 0 0 2 2 2 0 BNR/Asp-box repeat Amino_oxidase PF01593.19 OAJ29331.1 - 6.2e-58 196.9 0.1 1.8e-57 195.4 0.1 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAJ29331.1 - 2.7e-08 33.7 3.4 2.3e-07 30.7 2.4 2.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ29331.1 - 5.3e-07 28.8 2.1 4.9e-06 25.6 1.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAJ29331.1 - 0.0038 17.1 0.1 0.029 14.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAJ29331.1 - 0.0064 15.3 1.3 0.016 14.0 0.9 1.7 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 OAJ29331.1 - 0.0089 16.1 0.1 0.03 14.3 0.1 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ29331.1 - 0.039 13.0 0.1 0.078 12.0 0.1 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 OAJ29331.1 - 0.046 12.7 0.2 0.74 8.7 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 OAJ29331.1 - 0.07 13.5 0.1 22 5.5 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAJ29331.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 OAJ29331.1 - 0.26 9.7 0.1 3 6.2 0.0 2.6 4 0 0 4 4 4 0 HI0933-like protein Rubredoxin PF00301.15 OAJ29333.1 - 0.034 14.0 1.7 0.07 13.0 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin OAD_gamma PF04277.8 OAJ29334.1 - 0.023 15.0 1.0 9.4 6.6 0.0 2.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Nucleoplasmin PF03066.10 OAJ29334.1 - 0.26 10.8 4.1 0.43 10.0 2.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin Utp11 PF03998.8 OAJ29335.1 - 2.5e-50 171.6 12.9 4.8e-50 170.6 8.9 1.5 1 1 0 1 1 1 1 Utp11 protein Syntaxin_2 PF14523.1 OAJ29335.1 - 0.0086 16.0 2.1 0.14 12.2 0.0 2.7 3 0 0 3 3 3 1 Syntaxin-like protein Flu_NS2 PF00601.14 OAJ29335.1 - 0.12 12.5 0.7 10 6.4 0.1 2.5 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) Aa_trans PF01490.13 OAJ29336.1 - 7.9e-30 103.6 31.6 9.3e-30 103.4 21.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PsbI PF02532.9 OAJ29336.1 - 0.021 14.4 2.2 0.11 12.1 1.5 2.3 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Transposase_21 PF02992.9 OAJ29338.1 - 0.0015 17.6 0.1 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 TFIIA PF03153.8 OAJ29339.1 - 0.00038 20.4 28.5 0.00038 20.4 19.8 2.8 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 OAJ29339.1 - 0.0011 17.2 51.2 0.0011 17.2 35.5 2.6 2 1 1 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal Hid1 PF12722.2 OAJ29339.1 - 5 4.6 22.2 7.2 4.1 15.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 OAJ29339.1 - 5.1 4.6 17.5 6.9 4.2 12.1 1.1 1 0 0 1 1 1 0 Ycf1 RBP_receptor PF14752.1 OAJ29339.1 - 7.1 4.8 6.6 10 4.2 4.6 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor RR_TM4-6 PF06459.7 OAJ29339.1 - 7.1 6.4 19.2 18 5.1 13.3 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PLRV_ORF5 PF01690.12 OAJ29339.1 - 8.6 5.3 26.9 20 4.1 18.6 1.6 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DEAD PF00270.24 OAJ29340.1 - 2.9e-41 140.7 0.4 4.7e-41 140.0 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ29340.1 - 1e-23 82.9 0.1 2e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 OAJ29340.1 - 0.0013 17.8 0.1 0.0026 16.8 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Apolipoprotein PF01442.13 OAJ29341.1 - 0.00095 18.7 0.0 0.00095 18.7 0.0 6.1 3 2 0 4 4 4 1 Apolipoprotein A1/A4/E domain DUF1283 PF06932.6 OAJ29341.1 - 0.061 13.3 0.9 0.21 11.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) LEA_4 PF02987.11 OAJ29341.1 - 0.25 11.2 17.2 0.047 13.5 0.6 4.6 3 0 0 3 3 3 0 Late embryogenesis abundant protein Fungal_trans PF04082.13 OAJ29342.1 - 4.4e-10 38.8 0.0 9.3e-10 37.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ29342.1 - 7.1e-08 32.2 6.1 1.2e-07 31.4 4.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Init_tRNA_PT PF04179.7 OAJ29343.1 - 1.8e-98 330.3 0.0 2.2e-98 330.0 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Kinesin PF00225.18 OAJ29344.1 - 5.1e-93 311.4 0.0 8.1e-93 310.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain FlgN PF05130.7 OAJ29344.1 - 0.2 11.8 5.1 0.8 9.9 0.1 2.5 2 0 0 2 2 2 0 FlgN protein E1-E2_ATPase PF00122.15 OAJ29346.1 - 1.4e-58 197.6 0.1 1.4e-58 197.6 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAJ29346.1 - 2.2e-43 147.8 5.5 2.2e-43 147.8 3.8 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ29346.1 - 3.8e-26 92.8 0.1 2.5e-25 90.1 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ29346.1 - 4.1e-19 68.3 0.4 1.1e-18 66.9 0.3 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 OAJ29346.1 - 1.9e-15 57.5 0.0 6.3e-15 55.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAJ29346.1 - 7.3e-10 38.1 0.0 4.8e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 OAJ29346.1 - 9.8e-05 22.0 1.1 0.012 15.2 0.2 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Polysacc_deac_1 PF01522.16 OAJ29347.1 - 5.1e-17 61.6 0.0 1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 OAJ29347.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Glyco_transf_17 PF04724.8 OAJ29348.1 - 1.7e-94 316.7 0.0 2.1e-94 316.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 Glycos_transf_1 PF00534.15 OAJ29349.1 - 4.2e-30 104.4 0.1 3.4e-28 98.1 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 OAJ29349.1 - 2.7e-13 50.3 0.0 8.2e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 OAJ29349.1 - 2e-12 47.4 0.0 4.9e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 OAJ29349.1 - 1.2e-11 44.6 0.0 2.1e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 OAJ29349.1 - 7.3e-05 22.9 0.5 0.82 9.9 0.0 3.1 3 0 0 3 3 3 2 Glycosyl transferases group 1 APG5 PF04106.7 OAJ29350.1 - 6.7e-46 156.2 0.0 7.1e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 Autophagy protein Apg5 adh_short PF00106.20 OAJ29351.1 - 8.1e-06 25.8 0.2 0.00029 20.7 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ29351.1 - 0.083 12.6 0.0 0.23 11.1 0.0 1.6 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase RVT_1 PF00078.22 OAJ29353.1 - 4.7e-21 75.1 0.0 8e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ29353.1 - 3.9e-17 61.9 0.6 1.7e-16 59.8 0.1 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 OAJ29353.1 - 1.3e-14 54.6 0.1 4e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 RNase H Exo_endo_phos PF03372.18 OAJ29353.1 - 0.00014 21.8 0.4 0.00032 20.7 0.3 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 OAJ29353.1 - 0.043 14.1 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase NIF3 PF01784.13 OAJ29354.1 - 2.7e-56 190.8 0.0 3.4e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) COPIIcoated_ERV PF07970.7 OAJ29355.1 - 2.1e-37 128.9 0.2 3.2e-37 128.3 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 OAJ29355.1 - 7.9e-23 80.2 0.0 1.3e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) V-ATPase_H_N PF03224.9 OAJ29356.1 - 0.1 11.7 0.0 5.2 6.0 0.0 2.4 2 0 0 2 2 2 0 V-ATPase subunit H DUF1183 PF06682.7 OAJ29356.1 - 1.6 8.3 8.1 4.5 6.7 5.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Ycf1 PF05758.7 OAJ29356.1 - 4 5.0 5.7 5.6 4.5 4.0 1.1 1 0 0 1 1 1 0 Ycf1 Herpes_UL25 PF01499.11 OAJ29356.1 - 5.7 5.1 11.0 11 4.2 7.7 1.4 1 0 0 1 1 1 0 Herpesvirus UL25 family GRP PF07172.6 OAJ29356.1 - 7 7.1 17.9 0.31 11.5 8.2 1.9 2 0 0 2 2 2 0 Glycine rich protein family Cauli_VI PF01693.11 OAJ29357.1 - 0.003 17.5 0.0 0.0061 16.5 0.0 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin BSD PF03909.12 OAJ29358.1 - 4.6e-16 58.2 0.1 1.4e-11 43.9 0.0 2.6 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 OAJ29358.1 - 0.00024 20.6 0.0 0.00065 19.2 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF4632 PF15451.1 OAJ29358.1 - 5.6 6.9 7.2 4.5 7.2 1.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4632) Cauli_VI PF01693.11 OAJ29360.1 - 1.3e-16 60.3 0.8 1.5e-16 60.1 0.1 1.4 2 0 0 2 2 2 1 Caulimovirus viroplasmin Med9 PF07544.8 OAJ29361.1 - 0.021 14.5 2.6 0.32 10.7 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ATP-synt_D PF01813.12 OAJ29361.1 - 0.03 13.8 1.1 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 ATP synthase subunit D DUF4140 PF13600.1 OAJ29361.1 - 0.034 14.5 1.1 3.7 8.0 0.4 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Prefoldin_2 PF01920.15 OAJ29361.1 - 0.039 13.7 1.3 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit Prefoldin PF02996.12 OAJ29361.1 - 0.081 12.5 0.9 4.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit Peptidase_S15 PF02129.13 OAJ29361.1 - 0.17 11.2 0.3 0.2 11.0 0.2 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Laminin_I PF06008.9 OAJ29361.1 - 0.3 10.3 6.2 0.22 10.7 1.7 1.9 1 1 1 2 2 2 0 Laminin Domain I Mnd1 PF03962.10 OAJ29361.1 - 0.39 10.3 3.9 0.67 9.5 2.7 1.3 1 1 0 1 1 1 0 Mnd1 family IncA PF04156.9 OAJ29361.1 - 4.1 6.9 6.4 6.6 6.2 4.5 1.4 1 1 0 1 1 1 0 IncA protein Choline_transpo PF04515.7 OAJ29362.1 - 3.4e-25 88.4 9.1 9.5e-12 44.2 0.0 3.3 3 0 0 3 3 3 3 Plasma-membrane choline transporter SDA1 PF05285.7 OAJ29362.1 - 1.1 8.4 13.1 2.2 7.5 9.1 1.4 1 0 0 1 1 1 0 SDA1 Yippee-Mis18 PF03226.9 OAJ29363.1 - 1.6e-18 66.5 0.1 1.9e-18 66.2 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 OAJ29363.1 - 0.081 12.8 0.4 2.5 8.1 0.0 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DNA_RNApol_7kD PF03604.8 OAJ29363.1 - 0.099 12.1 1.1 1.3 8.6 0.1 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit YhfH PF14149.1 OAJ29363.1 - 0.18 11.6 1.7 0.5 10.2 0.0 2.3 2 0 0 2 2 2 0 YhfH-like protein F-box PF00646.28 OAJ29364.1 - 0.004 16.7 0.1 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain PI31_Prot_N PF11566.3 OAJ29365.1 - 7.7e-33 113.2 0.0 1e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 OAJ29365.1 - 5.1e-15 55.8 19.0 5.1e-15 55.8 13.2 2.9 3 0 0 3 3 3 1 PI31 proteasome regulator Aa_trans PF01490.13 OAJ29366.1 - 7e-72 242.1 18.9 9.8e-72 241.6 13.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 OAJ29366.1 - 2.6e-05 23.2 17.5 5.8e-05 22.0 12.1 1.7 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family SAM_1 PF00536.25 OAJ29367.1 - 0.00029 20.9 0.2 0.00064 19.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 OAJ29367.1 - 0.0034 17.1 0.1 0.0077 16.0 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Myb_DNA-binding PF00249.26 OAJ29368.1 - 2.2e-16 59.6 2.6 1.4e-11 44.2 0.2 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ29368.1 - 4.1e-10 39.6 11.9 6.2e-09 35.8 0.2 3.7 3 1 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ29368.1 - 0.0059 16.7 12.6 0.017 15.2 0.3 4.1 2 2 1 3 3 3 2 Myb/SANT-like DNA-binding domain DUF3782 PF12644.2 OAJ29368.1 - 0.18 11.6 1.5 0.37 10.6 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) Myb_DNA-binding PF00249.26 OAJ29369.1 - 3.8e-07 30.0 0.0 7.8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain GST_N_3 PF13417.1 OAJ29371.1 - 1.1e-17 64.0 0.0 2.3e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ29371.1 - 5.8e-10 39.0 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAJ29371.1 - 0.00032 20.5 0.5 0.0009 19.0 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 OAJ29371.1 - 0.03 14.4 0.0 0.13 12.4 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SHOCT PF09851.4 OAJ29372.1 - 0.34 10.4 0.0 0.81 9.2 0.0 1.7 1 0 0 1 1 1 0 Short C-terminal domain NOGCT PF08155.6 OAJ29373.1 - 1.9e-28 97.9 3.0 4.5e-28 96.7 2.1 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 OAJ29373.1 - 2.6e-28 97.6 0.1 4.5e-28 96.8 0.1 1.4 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 OAJ29373.1 - 5.7e-19 68.1 0.0 1.4e-18 66.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ29373.1 - 1.5e-09 37.3 0.0 2.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 OAJ29373.1 - 4.9e-05 23.8 0.0 0.00013 22.4 0.0 1.8 2 0 0 2 2 1 1 Miro-like protein Dynamin_N PF00350.18 OAJ29373.1 - 0.00075 19.3 0.0 0.63 9.8 0.0 2.8 1 1 1 2 2 2 2 Dynamin family DUF258 PF03193.11 OAJ29373.1 - 0.0029 16.7 0.0 0.044 12.9 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AIG1 PF04548.11 OAJ29373.1 - 0.046 12.8 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family COX16 PF14138.1 OAJ29373.1 - 0.079 13.1 0.1 0.44 10.7 0.1 2.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 SRPRB PF09439.5 OAJ29373.1 - 0.099 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MobB PF03205.9 OAJ29373.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 OAJ29373.1 - 0.12 12.5 0.0 0.95 9.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 OAJ29373.1 - 1.7 9.5 7.6 2.4 9.0 0.0 3.6 3 2 0 3 3 3 0 AAA domain Peptidase_M43 PF05572.8 OAJ29374.1 - 3.7e-18 65.5 0.0 5.9e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 OAJ29374.1 - 0.00026 21.4 0.4 0.0014 19.1 0.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 OAJ29374.1 - 0.0022 18.0 1.4 0.0033 17.5 1.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 OAJ29374.1 - 0.0039 16.7 0.4 0.0084 15.6 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAJ29374.1 - 0.031 14.1 2.5 0.054 13.4 1.7 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 OAJ29374.1 - 0.13 11.9 1.5 0.16 11.6 1.0 1.4 1 1 0 1 1 1 0 Matrixin Acetyltransf_1 PF00583.19 OAJ29375.1 - 6.6e-06 26.0 0.0 1.7e-05 24.7 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ29375.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain YjeF_N PF03853.10 OAJ29376.1 - 5.7e-36 123.6 0.0 7.9e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus WW PF00397.21 OAJ29377.1 - 1.4e-06 27.9 4.9 3.4e-06 26.8 3.4 1.7 1 0 0 1 1 1 1 WW domain Fringe PF02434.11 OAJ29378.1 - 4.8e-09 35.8 0.4 2.8e-08 33.2 0.3 2.2 1 1 0 1 1 1 1 Fringe-like eIF-3_zeta PF05091.7 OAJ29379.1 - 2e-143 478.7 0.0 3.8e-140 467.9 0.0 2.8 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ribosomal_60s PF00428.14 OAJ29379.1 - 6.7 7.1 17.8 31 5.0 7.3 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein Helicase_C_2 PF13307.1 OAJ29380.1 - 3.9e-54 183.0 0.0 8e-54 182.0 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 OAJ29380.1 - 7.8e-42 142.6 0.0 1.6e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 PhoH PF02562.11 OAJ29380.1 - 0.0078 15.4 0.1 1.3 8.1 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.1 OAJ29380.1 - 0.025 14.7 0.2 2.1 8.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Herpes_UL14 PF03580.9 OAJ29380.1 - 0.052 13.3 5.2 0.2 11.4 1.8 2.6 2 0 0 2 2 2 0 Herpesvirus UL14-like protein TFIIE-A_C-term PF11521.3 OAJ29380.1 - 7.1 6.6 10.2 20 5.2 0.4 3.9 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha RNase_H2-Ydr279 PF09468.5 OAJ29380.1 - 7.6 5.6 10.2 1 8.4 0.8 2.4 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) SNF2_N PF00176.18 OAJ29383.1 - 1e-70 237.9 0.0 1.9e-70 237.0 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ29383.1 - 2e-12 46.7 0.0 5.2e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ29383.1 - 2e-10 40.4 0.0 3.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 OAJ29383.1 - 1.6e-07 30.8 3.6 1.6e-07 30.8 2.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ29383.1 - 2.4e-07 30.6 5.1 2.4e-07 30.6 3.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAJ29383.1 - 4.2e-06 26.5 5.6 4.2e-06 26.5 3.9 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 OAJ29383.1 - 1.4e-05 24.8 6.5 1.4e-05 24.8 4.5 2.4 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAJ29383.1 - 2e-05 24.1 5.1 2e-05 24.1 3.6 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ29383.1 - 0.00013 21.6 5.8 0.00013 21.6 4.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ29383.1 - 0.00013 21.5 1.0 0.00037 20.1 0.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 OAJ29383.1 - 0.0012 18.5 3.6 0.0029 17.3 2.5 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-CHY PF05495.7 OAJ29383.1 - 1.3 9.1 11.2 0.052 13.7 1.5 2.5 2 0 0 2 2 2 0 CHY zinc finger Zn_Tnp_IS91 PF14319.1 OAJ29383.1 - 1.7 8.2 12.1 4.1 6.9 0.6 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain Ank_2 PF12796.2 OAJ29384.1 - 8.9e-13 48.3 0.0 6.1e-12 45.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ29384.1 - 6e-11 41.5 0.5 0.023 14.4 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 OAJ29384.1 - 1.8e-08 34.6 0.0 0.00045 20.6 0.0 4.0 2 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ29384.1 - 3.1e-06 27.2 0.3 0.065 13.5 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ29384.1 - 2.6e-05 24.0 0.0 1.1 9.6 0.0 5.0 6 0 0 6 6 6 1 Ankyrin repeat FMN_red PF03358.10 OAJ29385.1 - 6.9e-08 32.1 0.0 9.7e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 OAJ29385.1 - 4.9e-05 23.3 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_4 PF12682.2 OAJ29385.1 - 0.017 14.5 0.0 0.053 12.8 0.0 1.9 2 1 0 2 2 2 0 Flavodoxin zf-4CXXC_R1 PF10497.4 OAJ29386.1 - 1.3e-05 25.2 10.5 2.7e-05 24.2 7.3 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 FYVE_2 PF02318.11 OAJ29386.1 - 0.22 11.4 2.9 0.47 10.3 2.0 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger DUF3446 PF11928.3 OAJ29387.1 - 0.14 12.3 1.9 0.17 12.1 0.4 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3446) Hid1 PF12722.2 OAJ29388.1 - 2.1e-102 343.4 0.0 4.3e-88 296.0 0.0 3.2 2 2 0 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 OAJ29388.1 - 3e-37 128.1 0.0 7.2e-36 123.5 0.0 2.4 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF2360 PF10152.4 OAJ29388.1 - 9.2 6.5 9.1 0.55 10.4 1.1 2.8 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) SF-assemblin PF06705.6 OAJ29389.1 - 0.004 16.3 0.7 0.005 16.0 0.5 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Apolipoprotein PF01442.13 OAJ29389.1 - 0.017 14.6 0.1 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4366 PF14283.1 OAJ29389.1 - 0.076 12.4 1.5 0.093 12.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) SpoIIIAH PF12685.2 OAJ29389.1 - 0.16 11.4 3.7 0.22 10.9 2.5 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein ApoLp-III PF07464.6 OAJ29389.1 - 0.39 10.7 4.9 0.59 10.1 3.4 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Herpes_UL25 PF01499.11 OAJ29389.1 - 0.45 8.7 4.0 0.54 8.5 2.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Phasin PF05597.6 OAJ29389.1 - 0.49 10.1 5.7 14 5.4 3.9 2.1 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MRFAP1 PF15155.1 OAJ29389.1 - 2.6 8.4 6.6 0.96 9.7 2.3 1.6 1 1 1 2 2 2 0 MORF4 family-associated protein1 Mpv17_PMP22 PF04117.7 OAJ29390.1 - 8.2e-25 86.2 1.0 1.2e-24 85.7 0.7 1.2 1 0 0 1 1 1 1 Mpv17 / PMP22 family Zn_clus PF00172.13 OAJ29391.1 - 2.3e-08 33.7 12.6 3.7e-08 33.1 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4637 PF15470.1 OAJ29392.1 - 8.9 5.8 10.3 0.76 9.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) C5-epim_C PF06662.8 OAJ29393.1 - 0.11 11.7 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Hist_deacetyl PF00850.14 OAJ29395.1 - 2.6e-92 309.4 0.1 3.8e-92 308.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 OAJ29395.1 - 3.6e-15 55.8 0.0 6.8e-14 51.6 0.0 2.2 2 0 0 2 2 2 1 Arb2 domain DnaJ PF00226.26 OAJ29396.1 - 9.5e-23 79.7 1.1 1.5e-22 79.0 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain EF_assoc_1 PF08355.7 OAJ29397.1 - 0.00028 20.1 0.0 0.0005 19.3 0.0 1.4 1 0 0 1 1 1 1 EF hand associated Daxx PF03344.10 OAJ29397.1 - 0.031 12.7 5.3 0.049 12.1 3.7 1.3 1 0 0 1 1 1 0 Daxx Family DUF572 PF04502.8 OAJ29397.1 - 0.063 12.4 2.2 0.088 12.0 1.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Nop14 PF04147.7 OAJ29397.1 - 0.066 11.1 4.3 0.081 10.8 3.0 1.1 1 0 0 1 1 1 0 Nop14-like family Pol_alpha_B_N PF08418.5 OAJ29397.1 - 0.066 12.7 4.4 0.1 12.1 3.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Synaphin PF05835.7 OAJ29397.1 - 0.46 10.6 7.3 0.83 9.8 5.1 1.3 1 0 0 1 1 1 0 Synaphin protein DUF605 PF04652.11 OAJ29397.1 - 2.6 7.3 15.4 3.5 6.9 10.6 1.1 1 0 0 1 1 1 0 Vta1 like CDC45 PF02724.9 OAJ29397.1 - 3.1 5.7 5.1 3.8 5.4 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RGS PF00615.14 OAJ29398.1 - 1.1e-35 122.2 0.1 3.4e-25 88.4 0.0 3.6 3 1 0 3 3 3 2 Regulator of G protein signaling domain DEP PF00610.16 OAJ29398.1 - 1.8e-14 53.2 0.0 1.4e-07 31.1 0.0 2.7 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) rve PF00665.21 OAJ29399.1 - 8e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 OAJ29399.1 - 3.6e-06 26.5 0.0 7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Acid_PPase PF12689.2 OAJ29400.1 - 2.6e-52 176.8 0.0 6.8e-52 175.4 0.0 1.7 2 0 0 2 2 2 1 Acid Phosphatase RVT_1 PF00078.22 OAJ29400.1 - 3.2e-09 36.4 0.0 9.7e-09 34.8 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) HAD_2 PF13419.1 OAJ29400.1 - 0.00017 21.8 0.6 0.00092 19.4 0.0 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase NIF PF03031.13 OAJ29400.1 - 0.0081 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase gag-asp_proteas PF13975.1 OAJ29400.1 - 0.03 14.1 0.0 0.082 12.7 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 OAJ29400.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.18 OAJ29400.1 - 0.31 11.0 1.7 0.59 10.1 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle DPBB_1 PF03330.13 OAJ29401.1 - 6.9e-11 41.9 0.6 1.9e-10 40.5 0.4 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 OAJ29401.1 - 0.0054 16.7 0.6 0.025 14.5 0.0 2.2 2 0 0 2 2 2 1 Cerato-platanin Nop14 PF04147.7 OAJ29401.1 - 0.0081 14.1 19.2 0.01 13.8 13.3 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.4 OAJ29401.1 - 0.0082 14.9 21.4 0.011 14.4 14.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Daxx PF03344.10 OAJ29401.1 - 0.018 13.5 13.3 0.022 13.2 9.2 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 OAJ29401.1 - 0.043 13.0 12.5 0.054 12.7 8.6 1.2 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.8 OAJ29401.1 - 0.13 12.1 26.7 0.012 15.4 15.0 1.7 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.7 OAJ29401.1 - 0.81 9.3 15.7 1.3 8.7 10.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.7 OAJ29401.1 - 1.1 8.4 18.5 1.7 7.8 12.9 1.2 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.11 OAJ29401.1 - 1.7 7.5 14.4 2.8 6.8 10.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPP4R2 PF09184.6 OAJ29401.1 - 2.1 7.7 19.7 3.4 7.1 13.7 1.3 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.5 OAJ29401.1 - 6.2 5.7 18.0 8.6 5.3 12.5 1.2 1 0 0 1 1 1 0 BUD22 Rer1 PF03248.8 OAJ29402.1 - 3.1e-77 258.1 0.0 4.2e-77 257.7 0.0 1.2 1 0 0 1 1 1 1 Rer1 family GTP_EFTU PF00009.22 OAJ29404.1 - 1e-21 77.2 0.0 3e-21 75.6 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 OAJ29404.1 - 1.9e-09 37.5 0.9 5.5e-09 36.0 0.6 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 OAJ29404.1 - 4e-06 26.9 0.8 0.067 13.3 0.0 2.7 2 1 1 3 3 3 2 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 OAJ29404.1 - 0.0044 16.9 0.0 0.013 15.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 OAJ29404.1 - 0.005 16.3 0.2 8.7 5.8 0.0 3.5 2 1 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.1 OAJ29404.1 - 0.0078 15.8 1.6 0.023 14.3 0.2 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Erythro-docking PF09277.6 OAJ29404.1 - 0.03 13.9 0.1 0.077 12.6 0.0 1.7 1 0 0 1 1 1 0 Erythronolide synthase, docking Miro PF08477.8 OAJ29404.1 - 0.17 12.4 0.7 1.2 9.5 0.5 2.5 1 1 0 1 1 1 0 Miro-like protein CBS PF00571.23 OAJ29405.1 - 3.5e-16 58.7 6.0 3.8e-05 23.4 0.5 5.3 5 0 0 5 5 5 4 CBS domain SART-1 PF03343.8 OAJ29406.1 - 8.1e-109 364.6 52.9 9.7e-109 364.4 36.7 1.1 1 0 0 1 1 1 1 SART-1 family Actin PF00022.14 OAJ29407.1 - 1.3e-58 198.3 0.0 4.5e-34 117.5 0.0 2.2 2 0 0 2 2 2 2 Actin Cornichon PF03311.9 OAJ29408.1 - 1.5e-52 177.0 11.1 1.7e-52 176.8 7.7 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1673 PF07895.6 OAJ29408.1 - 0.25 10.8 9.0 0.67 9.4 6.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) DUF1634 PF07843.6 OAJ29408.1 - 1.3 8.6 6.0 0.12 11.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) MFS_1 PF07690.11 OAJ29409.1 - 3.2e-41 141.2 29.9 3.2e-41 141.2 20.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ29409.1 - 9.3e-11 40.9 3.5 9.3e-11 40.9 2.4 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 OAJ29409.1 - 4.6 5.1 8.2 5.2 4.9 0.0 2.7 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Mito_carr PF00153.22 OAJ29410.1 - 2.1e-63 210.0 3.3 5.3e-24 83.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3506 PF12014.3 OAJ29411.1 - 5.7e-11 42.3 0.0 1.8e-10 40.7 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 OAJ29411.1 - 3.9e-07 29.6 0.1 8.1e-07 28.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ29411.1 - 3.1e-05 23.5 0.0 6.9e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain Ribosomal_S17 PF00366.15 OAJ29412.1 - 1.8e-16 59.9 0.2 2.6e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 ALO PF04030.9 OAJ29413.1 - 5.8e-61 206.3 0.1 1.8e-52 178.5 0.0 2.5 3 0 0 3 3 3 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 OAJ29413.1 - 9.4e-18 64.0 0.0 9.4e-18 64.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Ras PF00071.17 OAJ29414.1 - 2.4e-50 170.0 0.0 3.3e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ29414.1 - 3.3e-17 63.0 0.0 4.6e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ29414.1 - 9.7e-06 24.9 0.0 1.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 OAJ29414.1 - 0.12 11.8 0.0 5.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF4349 PF14257.1 OAJ29414.1 - 0.14 11.3 3.5 0.19 10.8 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) SRPRB PF09439.5 OAJ29414.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit UBA_4 PF14555.1 OAJ29415.1 - 1.4e-08 34.0 0.2 2.2e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 UBA-like domain UIM PF02809.15 OAJ29415.1 - 0.0083 15.6 9.3 0.48 10.1 1.0 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif UBA PF00627.26 OAJ29415.1 - 0.032 14.0 0.0 0.095 12.5 0.0 1.8 2 0 0 2 2 2 0 UBA/TS-N domain Pkinase PF00069.20 OAJ29416.1 - 4e-68 229.3 0.0 5.9e-68 228.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ29416.1 - 5.1e-30 104.3 0.1 9e-29 100.3 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ29416.1 - 5.7e-07 28.7 1.7 0.00013 21.0 0.0 3.0 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 OAJ29416.1 - 0.017 14.1 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VWA_2 PF13519.1 OAJ29417.1 - 1.3e-11 44.8 0.0 2.1e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 OAJ29417.1 - 1.1e-05 25.2 0.0 4.6e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain Apt1 PF10351.4 OAJ29419.1 - 1.4e-104 350.5 0.2 1.4e-104 350.5 0.1 2.5 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 OAJ29419.1 - 1.1e-73 248.3 0.0 2.2e-73 247.3 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 OAJ29419.1 - 3.1e-42 144.1 0.0 6e-42 143.2 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 OAJ29419.1 - 1.1e-34 119.4 0.0 2.1e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 OAJ29419.1 - 1.6e-20 73.4 0.0 2.8e-19 69.4 0.0 2.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain PAH PF02671.16 OAJ29420.1 - 7.4e-44 147.1 3.3 5.2e-18 64.4 0.6 3.4 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 OAJ29420.1 - 3e-38 129.6 0.2 3e-38 129.6 0.1 2.5 3 0 0 3 3 3 1 Sin3 family co-repressor Sugar_tr PF00083.19 OAJ29421.1 - 3.6e-83 279.6 22.6 4.3e-83 279.3 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ29421.1 - 2.3e-16 59.4 40.8 3.2e-16 59.0 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zip PF02535.17 OAJ29422.1 - 0.52 9.2 9.8 0.013 14.5 2.0 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 OAJ29422.1 - 4.2 7.1 7.4 8.5 6.1 4.8 1.8 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HPHLAWLY PF14925.1 OAJ29423.1 - 0.37 8.7 10.6 0.85 7.5 7.4 1.5 1 0 0 1 1 1 0 Domain of unknown function Metallophos PF00149.23 OAJ29424.1 - 2.7e-43 147.6 0.1 3.4e-43 147.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DAO PF01266.19 OAJ29425.1 - 7.4e-14 51.4 3.4 5.9e-11 41.8 0.0 2.8 1 1 2 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAJ29425.1 - 0.0038 17.5 0.0 0.0074 16.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PIG-F PF06699.6 OAJ29426.1 - 3.6e-15 56.4 13.1 4.7e-14 52.7 9.1 2.2 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F Uroplakin_II PF07353.7 OAJ29426.1 - 9.6 5.5 8.9 0.39 10.0 2.0 1.6 2 0 0 2 2 2 0 Uroplakin II DUF3602 PF12223.3 OAJ29427.1 - 1.7e-12 47.5 25.6 1.1e-05 25.6 0.3 4.7 1 1 4 5 5 5 3 Protein of unknown function (DUF3602) Creb_binding PF09030.5 OAJ29427.1 - 0.02 15.0 0.2 0.9 9.7 0.0 2.4 2 0 0 2 2 2 0 Creb binding DUF1509 PF07420.6 OAJ29427.1 - 2.5 7.3 9.5 2.9 7.0 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) SOG2 PF10428.4 OAJ29428.1 - 0.97 8.0 8.3 1.4 7.5 5.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein eIF3_subunit PF08597.5 OAJ29428.1 - 1.8 8.0 14.0 0.53 9.8 0.2 2.3 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit Tau95 PF09734.4 OAJ29429.1 - 1.9e-42 145.6 0.0 4.1e-42 144.5 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Suc_Fer-like PF06999.7 OAJ29430.1 - 9.6e-30 104.3 0.0 1.2e-28 100.7 0.0 2.3 1 1 0 1 1 1 1 Sucrase/ferredoxin-like BAR_2 PF10455.4 OAJ29430.1 - 0.044 12.7 1.2 0.065 12.1 0.8 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking FAD-SLDH PF12318.3 OAJ29430.1 - 0.15 11.7 0.9 0.29 10.8 0.6 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF3552 PF12072.3 OAJ29430.1 - 0.17 11.0 6.3 0.27 10.4 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2347 PF09804.4 OAJ29430.1 - 0.37 10.0 2.3 0.57 9.4 1.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Mannosyl_trans2 PF04188.8 OAJ29432.1 - 4.3e-58 197.2 5.5 6.9e-58 196.6 3.8 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) GSAP-16 PF14959.1 OAJ29432.1 - 0.028 14.1 0.4 0.049 13.3 0.3 1.3 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term LIP PF03583.9 OAJ29433.1 - 1.4e-60 205.0 0.0 1.8e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_3 PF07859.8 OAJ29434.1 - 3.7e-19 69.1 0.0 5.3e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAJ29434.1 - 1.7e-09 36.7 0.0 0.00034 19.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 OAJ29434.1 - 0.0064 16.2 0.0 0.0094 15.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1776 PF08643.5 OAJ29435.1 - 0.001 18.2 0.0 0.085 11.9 0.0 2.2 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) JAB PF01398.16 OAJ29436.1 - 7.2e-35 119.1 0.1 1.5e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 OAJ29436.1 - 2.3e-25 88.9 1.2 6.1e-25 87.5 0.8 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 OAJ29436.1 - 6.1e-08 32.1 0.0 9.3e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain CN_hydrolase PF00795.17 OAJ29437.1 - 5e-25 87.9 0.0 7.7e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PH PF00169.24 OAJ29438.1 - 1.2e-07 31.8 0.1 2.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 OAJ29438.1 - 0.15 12.3 1.8 0.19 12.0 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Abhydrolase_3 PF07859.8 OAJ29439.1 - 2e-18 66.7 0.0 1.5e-17 63.8 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAJ29439.1 - 6.9e-10 38.1 0.0 6.3e-07 28.3 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF2424) SAPS PF04499.10 OAJ29439.1 - 1.1 7.7 13.2 2.3 6.7 9.2 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.11 OAJ29439.1 - 1.3 8.8 9.2 0.029 14.2 0.4 2.6 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 OAJ29439.1 - 2.3 5.7 16.8 4.5 4.8 11.6 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LSM PF01423.17 OAJ29440.1 - 1.3e-15 56.6 0.1 1.7e-15 56.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain Peptidase_M3 PF01432.15 OAJ29440.1 - 0.086 11.8 0.2 0.096 11.7 0.2 1.0 1 0 0 1 1 1 0 Peptidase family M3 polyprenyl_synt PF00348.12 OAJ29441.1 - 3e-06 26.2 0.0 3.9e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Thy1 PF02511.10 OAJ29441.1 - 0.078 12.3 0.0 0.083 12.2 0.0 1.1 1 0 0 1 1 1 0 Thymidylate synthase complementing protein PCI PF01399.22 OAJ29442.1 - 1.6e-05 25.1 0.0 3.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain K_channel_TID PF07941.6 OAJ29442.1 - 5.8 7.2 10.5 0.41 10.8 0.4 3.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain BCDHK_Adom3 PF10436.4 OAJ29445.1 - 5.9e-62 208.0 0.0 8.8e-62 207.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 OAJ29445.1 - 3e-19 68.7 0.0 5.2e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAJ29445.1 - 3.9e-06 26.5 0.0 6.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC27 PF09507.5 OAJ29446.1 - 1.3e-34 120.2 71.0 1.5e-21 77.1 0.0 4.2 1 1 2 3 3 3 3 DNA polymerase subunit Cdc27 Serglycin PF04360.7 OAJ29446.1 - 0.25 11.0 5.7 0.14 11.9 1.0 2.3 2 0 0 2 2 2 0 Serglycin AFG1_ATPase PF03969.11 OAJ29447.1 - 2.2e-85 286.6 0.0 1.7e-80 270.5 0.0 3.1 3 0 0 3 3 3 3 AFG1-like ATPase AAA_22 PF13401.1 OAJ29447.1 - 0.00012 22.2 0.0 0.0005 20.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ29447.1 - 0.0012 18.8 0.1 0.029 14.3 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 OAJ29447.1 - 0.036 14.2 0.0 2.8 8.1 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.16 OAJ29447.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain DEAD PF00270.24 OAJ29449.1 - 3e-33 114.6 0.1 4.8e-32 110.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ29449.1 - 1.3e-25 89.0 0.2 2.2e-25 88.3 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 OAJ29449.1 - 3.9e-05 23.6 0.0 7.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain AAA_22 PF13401.1 OAJ29449.1 - 0.099 12.7 0.6 0.71 10.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain SUI1 PF01253.17 OAJ29450.1 - 1.3e-15 56.9 0.0 4.8e-15 55.1 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor SUI1 HTH_Tnp_1 PF01527.15 OAJ29450.1 - 0.1 12.5 3.5 0.77 9.7 0.2 2.9 1 1 1 2 2 2 0 Transposase GATase PF00117.23 OAJ29451.1 - 2.7e-08 33.4 0.0 3.2e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 OAJ29451.1 - 0.057 12.8 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase C26 DEAD PF00270.24 OAJ29452.1 - 4.2e-45 153.2 0.0 3.6e-44 150.2 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ29452.1 - 8e-23 80.1 0.0 2.3e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ29452.1 - 0.0025 17.6 0.0 0.01 15.7 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2285 PF10074.4 OAJ29452.1 - 0.007 16.6 4.8 0.028 14.7 1.6 2.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2285) CMS1 PF14617.1 OAJ29452.1 - 0.028 13.4 0.0 0.14 11.1 0.0 2.1 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit zf-CCHC_2 PF13696.1 OAJ29452.1 - 0.13 11.8 0.8 0.35 10.3 0.6 1.7 1 0 0 1 1 1 0 Zinc knuckle Helicase_C_2 PF13307.1 OAJ29452.1 - 0.14 12.0 0.3 1.7 8.5 0.0 2.4 1 1 1 2 2 2 0 Helicase C-terminal domain zf-CCHC PF00098.18 OAJ29452.1 - 0.19 11.6 1.8 0.32 11.0 1.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ29452.1 - 0.23 11.1 1.3 0.54 9.9 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle AD PF09793.4 OAJ29453.1 - 1.3e-18 66.5 0.0 2.3e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain H_lectin PF09458.5 OAJ29456.1 - 4.9e-05 22.8 0.0 0.001 18.6 0.0 2.8 2 0 0 2 2 2 1 H-type lectin domain RNase_PH_C PF03725.10 OAJ29456.1 - 0.012 15.5 0.1 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Jacalin PF01419.12 OAJ29457.1 - 1.7e-06 27.9 0.0 0.0019 18.0 0.0 2.6 2 0 0 2 2 2 2 Jacalin-like lectin domain DUF377 PF04041.8 OAJ29459.1 - 0.015 14.0 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF377) RabGAP-TBC PF00566.13 OAJ29460.1 - 1e-15 57.8 0.0 4.3e-06 26.3 0.0 3.6 3 1 0 3 3 3 3 Rab-GTPase-TBC domain Cofilin_ADF PF00241.15 OAJ29461.1 - 3.1e-10 40.0 0.0 3.4e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein IBR PF01485.16 OAJ29462.1 - 1.2e-20 73.1 45.8 2.5e-12 46.4 4.8 4.5 3 1 1 4 4 4 2 IBR domain zf-C3HC4 PF00097.20 OAJ29462.1 - 0.00036 20.1 5.8 0.00036 20.1 4.0 4.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ29462.1 - 0.0014 18.4 5.6 0.0014 18.4 3.9 3.8 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ29462.1 - 0.0014 18.6 5.1 0.0014 18.6 3.5 4.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 OAJ29462.1 - 1.3 8.6 33.4 1.1 8.8 3.3 4.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 OAJ29462.1 - 8.5 6.3 29.7 0.2 11.5 0.6 4.6 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING FAD_binding_3 PF01494.14 OAJ29465.1 - 1.1e-24 87.1 0.0 1.5e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAJ29465.1 - 0.00048 20.0 0.0 0.0045 16.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ29465.1 - 0.0031 17.8 0.1 0.049 14.0 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ29465.1 - 0.009 14.9 0.9 0.19 10.6 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.5 OAJ29465.1 - 0.023 13.5 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase ApbA PF02558.11 OAJ29465.1 - 0.034 13.5 0.1 0.064 12.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.1 OAJ29465.1 - 0.044 13.8 0.1 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Autophagy_N PF03986.8 OAJ29465.1 - 0.048 13.4 0.1 0.096 12.4 0.1 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain Ribonuc_red_lgC PF02867.10 OAJ29466.1 - 1.7e-210 700.2 0.0 2.2e-210 699.8 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 OAJ29466.1 - 3.4e-24 84.4 0.0 7.4e-24 83.3 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 OAJ29466.1 - 2e-17 63.4 0.3 7.1e-17 61.6 0.2 2.1 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.1 OAJ29466.1 - 0.0017 16.4 0.0 0.0028 15.8 0.0 1.3 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase DisA_N PF02457.11 OAJ29466.1 - 0.023 13.8 0.0 0.056 12.5 0.0 1.6 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding IPK PF03770.11 OAJ29467.1 - 3.9e-36 124.5 0.0 1.7e-21 76.7 0.0 2.1 2 0 0 2 2 2 2 Inositol polyphosphate kinase DcpS_C PF11969.3 OAJ29468.1 - 4.2e-27 94.6 0.0 6.6e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 OAJ29468.1 - 9.5e-21 74.2 0.0 1.8e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal WD40 PF00400.27 OAJ29469.1 - 1.6e-15 56.2 0.6 1.2e-05 25.0 0.1 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat GTP_EFTU PF00009.22 OAJ29470.1 - 3.2e-56 189.7 0.0 4.9e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 OAJ29470.1 - 1.6e-35 121.1 0.1 4.2e-35 119.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 OAJ29470.1 - 5.1e-16 58.5 1.0 5.1e-16 58.5 0.7 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 OAJ29470.1 - 0.00095 18.7 0.4 0.0026 17.3 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 OAJ29470.1 - 0.002 18.0 0.5 0.0073 16.2 0.3 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 OAJ29470.1 - 0.083 12.4 0.2 4 7.0 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Hpt PF01627.18 OAJ29471.1 - 5.2e-11 42.4 0.1 9.8e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Hpt domain Med3 PF11593.3 OAJ29471.1 - 1.1 8.3 5.8 1.1 8.3 4.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF605 PF04652.11 OAJ29471.1 - 2.5 7.3 13.6 3 7.1 9.5 1.2 1 0 0 1 1 1 0 Vta1 like Abhydrolase_6 PF12697.2 OAJ29472.1 - 4.3e-22 79.1 0.2 7.1e-22 78.4 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ29472.1 - 2.1e-08 34.0 0.1 4.9e-08 32.8 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ29472.1 - 3.5e-06 26.7 0.0 9.6e-06 25.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAR PF03114.13 OAJ29473.1 - 1.7e-11 44.0 1.4 2.9e-11 43.3 1.0 1.3 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 OAJ29473.1 - 0.00015 20.7 0.2 0.0003 19.8 0.2 1.5 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking RNase_PH PF01138.16 OAJ29474.1 - 2.5e-22 79.6 0.0 4.1e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 EMG1 PF03587.9 OAJ29476.1 - 3.9e-75 251.5 0.0 5e-75 251.2 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Med10 PF09748.4 OAJ29477.1 - 5.7e-15 55.2 0.0 7.1e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PP2C PF00481.16 OAJ29478.1 - 8.4e-68 228.5 0.4 1.1e-51 175.6 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Arf PF00025.16 OAJ29479.1 - 3.5e-77 257.5 0.0 4e-77 257.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 OAJ29479.1 - 6.2e-13 48.4 0.0 6.7e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 OAJ29479.1 - 2e-11 43.4 0.0 2.5e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 OAJ29479.1 - 2.6e-11 42.8 0.8 2.6e-07 29.7 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 OAJ29479.1 - 4.3e-10 39.1 0.0 5.2e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 OAJ29479.1 - 1.3e-07 32.0 0.0 1.8e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 OAJ29479.1 - 0.00013 21.9 0.0 0.00032 20.6 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 OAJ29479.1 - 0.00083 18.4 0.1 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 OAJ29479.1 - 0.013 14.9 0.0 0.098 12.0 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Methyltransf_31 PF13847.1 OAJ29480.1 - 1.3e-17 63.7 0.0 1.7e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ29480.1 - 2e-14 53.8 0.0 3.6e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ29480.1 - 1.4e-13 51.3 0.0 2.5e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ29480.1 - 1.3e-12 48.0 0.0 1.9e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ29480.1 - 3.3e-10 39.9 0.0 4.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ29480.1 - 8.2e-09 35.5 0.1 1.5e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ29480.1 - 5.3e-08 33.1 0.0 8.1e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ29480.1 - 1.4e-06 27.8 0.0 4e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 OAJ29480.1 - 2.4e-06 27.2 0.0 3.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PCMT PF01135.14 OAJ29480.1 - 2.9e-06 26.9 0.0 4.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 OAJ29480.1 - 3.8e-05 22.9 0.0 4.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 OAJ29480.1 - 0.00013 21.2 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 OAJ29480.1 - 0.0011 18.1 0.0 0.0022 17.1 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 OAJ29480.1 - 0.0029 17.3 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 OAJ29480.1 - 0.0098 15.1 0.0 0.78 8.9 0.0 2.1 1 1 0 1 1 1 1 CheR methyltransferase, SAM binding domain RrnaAD PF00398.15 OAJ29480.1 - 0.041 12.9 0.0 0.068 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase N6_Mtase PF02384.11 OAJ29480.1 - 0.045 12.8 0.0 0.052 12.6 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_9 PF08003.6 OAJ29480.1 - 0.046 12.4 0.1 0.069 11.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.12 OAJ29480.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Acetyltransf_5 PF13444.1 OAJ29481.1 - 0.0001 22.7 0.0 0.00074 20.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAJ29481.1 - 0.072 13.1 0.2 0.16 11.9 0.1 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family AA_permease PF00324.16 OAJ29483.1 - 8.4e-65 218.9 32.9 1.1e-64 218.5 22.8 1.1 1 0 0 1 1 1 1 Amino acid permease Glypican PF01153.14 OAJ29483.1 - 6.1 5.3 5.7 20 3.6 3.9 1.8 1 0 0 1 1 1 0 Glypican UBN2 PF14223.1 OAJ29484.1 - 3.1e-05 23.7 0.0 5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ29484.1 - 0.0018 18.0 6.0 0.0033 17.2 4.2 1.5 1 0 0 1 1 1 1 Zinc knuckle UBN2_2 PF14227.1 OAJ29484.1 - 0.054 13.0 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type MFS_1 PF07690.11 OAJ29485.1 - 5.3e-37 127.3 36.6 5.3e-37 127.3 25.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ29485.1 - 8.5e-07 27.9 13.9 8.5e-07 27.9 9.7 2.5 3 1 0 3 3 3 1 Sugar (and other) transporter POX PF07526.6 OAJ29485.1 - 0.54 10.4 2.4 0.78 9.9 1.6 1.2 1 0 0 1 1 1 0 Associated with HOX Gar1 PF04410.9 OAJ29486.1 - 4.9e-38 130.0 0.0 4.9e-38 130.0 0.0 2.5 1 1 3 4 4 4 1 Gar1/Naf1 RNA binding region vWA-TerF-like PF10138.4 OAJ29487.1 - 0.00084 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus T2SS-T3SS_pil_N PF13629.1 OAJ29487.1 - 0.058 12.9 0.1 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 Pilus formation protein N terminal region VWA_3 PF13768.1 OAJ29487.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.23 OAJ29487.1 - 0.076 12.7 0.1 0.39 10.4 0.1 2.0 1 1 0 1 1 1 0 von Willebrand factor type A domain Collagen PF01391.13 OAJ29488.1 - 5.2e-07 29.1 17.5 8.2e-07 28.4 12.1 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF378 PF04070.7 OAJ29488.1 - 2.7 7.6 4.6 27 4.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF378) RVT_2 PF07727.9 OAJ29489.1 - 5.8e-81 271.0 0.0 8.4e-81 270.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ29489.1 - 2.4e-25 88.9 0.0 6.3e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ29489.1 - 2.1e-07 30.4 0.0 4.8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ29489.1 - 9.2e-05 21.8 0.0 0.00023 20.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Meckelin PF09773.4 OAJ29489.1 - 0.017 12.9 0.1 0.023 12.4 0.1 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) RQC PF09382.5 OAJ29490.1 - 6.2e-23 80.5 0.1 1.2e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 OAJ29490.1 - 5e-20 71.6 0.0 1.3e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ29490.1 - 1.1e-19 70.0 0.0 1.9e-18 66.0 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.18 OAJ29490.1 - 1.8e-10 40.3 0.0 4.4e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Ribosomal_S9 PF00380.14 OAJ29491.1 - 9.8e-36 122.6 0.0 2e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Fungal_trans PF04082.13 OAJ29492.1 - 9.7e-19 67.2 0.0 3.1e-18 65.5 0.0 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain His_Phos_2 PF00328.17 OAJ29494.1 - 1.8e-69 234.7 0.3 2.6e-69 234.2 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 OAJ29494.1 - 1.1e-06 28.2 0.0 2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Sterol-sensing PF12349.3 OAJ29495.1 - 1.1e-38 132.1 12.9 2.7e-38 130.8 8.9 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 OAJ29495.1 - 4.4e-12 44.7 5.1 6.4e-12 44.2 3.5 1.1 1 0 0 1 1 1 1 Patched family Abhydrolase_1 PF00561.15 OAJ29496.1 - 8.8e-14 51.6 0.4 3.2e-11 43.2 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ29496.1 - 4.2e-09 36.6 3.6 1e-07 32.1 2.5 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ29496.1 - 0.00066 19.4 0.0 0.029 14.1 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAJ29496.1 - 0.0024 17.3 0.1 0.0042 16.5 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Erg28 PF03694.8 OAJ29498.1 - 7e-42 141.9 2.2 8.5e-42 141.6 1.5 1.1 1 0 0 1 1 1 1 Erg28 like protein S1FA PF04689.8 OAJ29498.1 - 0.049 13.5 0.2 4.1 7.3 0.0 2.2 2 0 0 2 2 2 0 DNA binding protein S1FA zf-DHHC PF01529.15 OAJ29499.1 - 1.1e-31 109.5 3.8 1.3e-31 109.3 1.7 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase zf-tcix PF14952.1 OAJ29499.1 - 0.04 13.2 1.2 0.084 12.2 0.8 1.5 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding FA_desaturase PF00487.19 OAJ29499.1 - 0.067 12.6 0.6 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Fatty acid desaturase Chorismate_bind PF00425.13 OAJ29501.1 - 2.4e-88 295.8 0.2 5.3e-88 294.6 0.0 1.6 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 OAJ29501.1 - 1.8e-25 89.5 0.0 1.3e-24 86.8 0.0 2.4 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region PRP21_like_P PF12230.3 OAJ29502.1 - 1.6e-56 191.3 0.5 1.6e-56 191.3 0.4 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 OAJ29502.1 - 3.5e-32 109.8 0.3 3.2e-16 58.7 0.0 2.5 2 0 0 2 2 2 2 Surp module SAC3_GANP PF03399.11 OAJ29504.1 - 4.7e-43 147.1 0.0 8.2e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family BRCT PF00533.21 OAJ29505.1 - 8.9e-27 93.0 0.0 2.6e-10 40.2 0.0 5.3 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 OAJ29505.1 - 1.7e-23 82.2 0.0 3e-10 39.8 0.0 4.4 4 0 0 4 4 4 3 twin BRCT domain Abhydrolase_3 PF07859.8 OAJ29506.1 - 2.6e-06 27.1 0.4 6.4e-06 25.8 0.3 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ29506.1 - 0.00038 20.2 0.0 0.00061 19.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ29506.1 - 0.00082 19.3 3.6 0.0012 18.8 2.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 OAJ29506.1 - 0.062 12.7 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) EI24 PF07264.6 OAJ29507.1 - 7e-24 84.4 13.1 1.1e-23 83.8 9.1 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DAP PF15228.1 OAJ29508.1 - 0.13 13.0 0.3 0.13 13.0 0.2 2.8 3 1 0 3 3 3 0 Death-associated protein SelP_N PF04592.9 OAJ29508.1 - 1.4 8.2 4.7 2 7.7 3.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HsbA PF12296.3 OAJ29509.1 - 0.00095 19.0 3.2 0.0017 18.1 2.2 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Cpn60_TCP1 PF00118.19 OAJ29510.1 - 1.5e-141 472.3 11.9 1.8e-141 472.1 8.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 OAJ29510.1 - 0.00095 18.4 0.1 0.004 16.4 0.0 2.1 2 0 0 2 2 2 1 Telomere recombination SNF2_N PF00176.18 OAJ29511.1 - 1.2e-76 257.4 0.1 2.3e-76 256.4 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.8 OAJ29511.1 - 7.3e-19 67.3 9.8 3.1e-18 65.3 6.8 2.2 1 0 0 1 1 1 1 HSA Helicase_C PF00271.26 OAJ29511.1 - 3e-18 65.4 0.0 6.3e-17 61.2 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.20 OAJ29511.1 - 7.3e-17 61.0 0.4 1.8e-16 59.7 0.3 1.8 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 OAJ29511.1 - 1.4e-14 53.9 1.1 1.4e-14 53.9 0.8 3.4 2 1 1 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 OAJ29511.1 - 5.1e-11 41.7 2.9 1.4e-10 40.4 2.0 1.8 1 0 0 1 1 1 1 QLQ DUF3085 PF11284.3 OAJ29511.1 - 0.06 13.5 0.1 16 5.7 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3085) 4HBT_2 PF13279.1 OAJ29513.1 - 6.3e-05 23.4 0.0 0.00012 22.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily PNP_UDP_1 PF01048.15 OAJ29514.1 - 2.1e-23 82.5 0.1 2.5e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Methyltransf_16 PF10294.4 OAJ29515.1 - 3.9e-15 55.7 0.0 7.7e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 OAJ29515.1 - 0.016 15.8 0.1 0.072 13.6 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ29515.1 - 0.079 13.3 0.0 0.22 11.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ29515.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SPO22 PF08631.5 OAJ29516.1 - 8.2e-07 28.3 0.1 8.2e-07 28.3 0.1 3.2 3 1 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_11 PF13414.1 OAJ29516.1 - 0.039 13.5 7.6 3 7.5 0.7 4.2 3 1 1 4 4 4 0 TPR repeat TPR_6 PF13174.1 OAJ29516.1 - 1.5 9.4 9.2 7.3 7.2 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_S8e PF01201.17 OAJ29517.1 - 1.1e-49 167.9 1.6 1.4e-49 167.6 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e TCTP PF00838.12 OAJ29518.1 - 5.1e-63 211.9 0.4 5.7e-63 211.7 0.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Csm1 PF12539.3 OAJ29519.1 - 1.7e-06 28.4 0.0 1.2e-05 25.7 0.0 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 AIP3 PF03915.8 OAJ29519.1 - 0.29 10.0 12.3 0.12 11.1 6.8 1.6 1 1 0 1 1 1 0 Actin interacting protein 3 HAUS6_N PF14661.1 OAJ29519.1 - 0.35 10.1 17.4 0.069 12.4 2.6 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus IncA PF04156.9 OAJ29519.1 - 0.7 9.4 19.7 0.61 9.6 4.9 2.2 2 0 0 2 2 2 0 IncA protein Fib_alpha PF08702.5 OAJ29519.1 - 0.92 9.6 7.8 0.93 9.6 1.3 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RTBV_P46 PF06216.6 OAJ29519.1 - 1.6 7.4 5.8 1.2 7.9 0.3 2.1 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein Tropomyosin PF00261.15 OAJ29519.1 - 1.8 7.5 29.6 2.1 7.3 2.9 3.1 2 1 1 3 3 3 0 Tropomyosin DUF1515 PF07439.6 OAJ29519.1 - 3.1 7.6 10.2 1.3 8.8 1.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Dsh_C PF12316.3 OAJ29519.1 - 3.6 7.6 19.1 2.4 8.2 3.4 2.4 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Ax_dynein_light PF10211.4 OAJ29519.1 - 6.9 6.4 22.3 2.4 7.9 3.2 2.8 2 1 1 3 3 3 0 Axonemal dynein light chain Nop52 PF05997.7 OAJ29520.1 - 6e-51 172.9 0.0 9e-44 149.4 0.0 2.2 2 0 0 2 2 2 2 Nucleolar protein,Nop52 Peptidase_C8 PF03569.8 OAJ29520.1 - 0.12 11.6 0.1 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase family C8 HMG_box PF00505.14 OAJ29521.1 - 1.9e-18 66.5 6.6 3.2e-10 40.1 1.4 3.5 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ29521.1 - 3.9e-10 39.9 4.2 3.8e-07 30.3 0.1 3.4 3 1 0 3 3 3 2 HMG-box domain DUF3106 PF11304.3 OAJ29521.1 - 1 9.8 13.4 0.49 10.8 1.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) Pro_isomerase PF00160.16 OAJ29522.1 - 1.1e-37 129.6 0.0 7.1e-37 127.0 0.0 2.1 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.1 OAJ29522.1 - 0.018 15.2 0.1 0.018 15.2 0.1 3.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4604) SBDS_C PF09377.5 OAJ29524.1 - 1.2e-42 144.4 0.8 1.7e-42 144.0 0.5 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 OAJ29524.1 - 4.9e-16 58.2 0.3 1.3e-15 56.9 0.1 1.8 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein 2-Hacid_dh_C PF02826.14 OAJ29524.1 - 0.073 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.27 OAJ29525.1 - 3.5e-21 74.2 6.9 9.4e-11 41.1 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Pkinase PF00069.20 OAJ29525.1 - 2.7e-16 59.5 0.0 5.6e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ29525.1 - 1.3e-07 30.9 0.0 0.00093 18.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT PF02985.17 OAJ29525.1 - 5.7e-07 29.0 11.1 0.018 15.0 0.4 6.5 6 0 0 6 6 6 1 HEAT repeat Nucleoporin_N PF08801.6 OAJ29525.1 - 0.0019 16.9 2.4 0.21 10.3 0.5 3.3 2 2 2 4 4 4 2 Nup133 N terminal like Cohesin_HEAT PF12765.2 OAJ29525.1 - 0.28 11.1 2.5 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 OAJ29525.1 - 0.49 8.6 0.4 1.3 7.2 0.2 1.6 2 0 0 2 2 2 0 Adaptin N terminal region Myb_DNA-bind_4 PF13837.1 OAJ29527.1 - 0.0084 16.2 0.5 0.1 12.7 0.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MFS_1 PF07690.11 OAJ29529.1 - 4.3e-27 94.7 25.5 4.3e-27 94.7 17.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PfkB PF00294.19 OAJ29530.1 - 4.1e-17 62.2 0.0 2.9e-12 46.3 0.0 2.0 1 1 1 2 2 2 2 pfkB family carbohydrate kinase COX7C PF02935.11 OAJ29530.1 - 0.06 13.1 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc Zn_clus PF00172.13 OAJ29531.1 - 4e-07 29.8 9.1 6.7e-07 29.1 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1777 PF08648.7 OAJ29531.1 - 0.0002 21.1 23.8 0.0002 21.1 16.5 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1777) Fungal_trans PF04082.13 OAJ29531.1 - 0.00038 19.4 0.2 0.03 13.1 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Ribonuc_red_sm PF00268.16 OAJ29532.1 - 1e-119 398.7 1.8 1.2e-119 398.4 1.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Transposase_21 PF02992.9 OAJ29533.1 - 9.4e-08 31.4 0.0 1.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ29533.1 - 4.1e-06 26.2 0.0 7.6e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) ORC6 PF05460.8 OAJ29533.1 - 1.1 8.2 14.4 2.6 7.0 0.1 2.5 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) RVT_2 PF07727.9 OAJ29534.1 - 5.2e-90 300.7 0.0 7.2e-90 300.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ29534.1 - 7.9e-20 71.1 0.0 7.1e-19 68.0 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ29534.1 - 1.3e-05 24.7 0.0 5.3e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain UBN2 PF14223.1 OAJ29535.1 - 2.6e-05 23.9 0.0 4.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ29535.1 - 0.28 11.1 2.2 0.53 10.3 1.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Got1 PF04178.7 OAJ29536.1 - 1.6e-22 79.7 22.3 2.3e-22 79.3 15.5 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Herpes_capsid PF06112.6 OAJ29536.1 - 4.5 7.3 5.7 5.6 7.0 4.0 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF4187 PF13821.1 OAJ29537.1 - 1.8e-15 56.2 4.9 4.5e-15 54.9 3.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 OAJ29537.1 - 0.12 12.1 0.1 0.41 10.4 0.0 1.8 1 0 0 1 1 1 0 G-patch domain AP-5_subunit_s1 PF15001.1 OAJ29537.1 - 0.53 10.1 2.2 1.2 9.0 1.5 1.6 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Pectate_lyase_3 PF12708.2 OAJ29538.1 - 7.7e-69 232.2 8.0 2.6e-51 174.9 2.2 2.6 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 OAJ29538.1 - 0.00024 20.4 4.1 0.047 13.1 0.0 3.3 4 0 0 4 4 4 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 OAJ29538.1 - 0.0022 17.7 2.7 0.0089 15.7 1.9 2.2 1 0 0 1 1 1 1 Right handed beta helix region Trypan_PARP PF05887.6 OAJ29538.1 - 0.18 11.6 3.6 0.43 10.3 2.5 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.7 OAJ29538.1 - 0.61 7.9 9.7 0.86 7.4 6.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 OAJ29538.1 - 4.1 5.3 9.9 6.3 4.6 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 OAJ29538.1 - 9.6 4.8 21.3 17 3.9 14.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GST_N PF02798.15 OAJ29539.1 - 5.5e-13 48.8 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 OAJ29539.1 - 1.5e-10 41.1 0.0 2.6e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ29539.1 - 2.1e-10 40.4 0.0 3.8e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ29539.1 - 4.4e-10 39.4 0.0 6.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ29539.1 - 2.7e-08 33.5 0.1 4.9e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ29539.1 - 3.4e-06 27.4 0.2 5.6e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MCM PF00493.18 OAJ29540.1 - 9.5e-132 438.7 0.0 3.2e-131 437.0 0.0 1.7 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 OAJ29540.1 - 1e-25 90.5 0.0 2.2e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.9 OAJ29540.1 - 1.2e-07 31.5 0.0 2.6e-05 23.9 0.0 2.6 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 OAJ29540.1 - 7e-07 28.6 0.0 5e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Mg_chelatase_2 PF13335.1 OAJ29540.1 - 0.003 17.8 0.2 0.0086 16.4 0.1 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 OAJ29540.1 - 0.03 13.9 0.0 0.088 12.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hexokinase_1 PF00349.16 OAJ29541.1 - 7.3e-64 214.8 0.0 1e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 OAJ29541.1 - 1.9e-61 207.3 0.4 3.5e-45 154.1 0.0 2.1 2 0 0 2 2 2 2 Hexokinase Thiolase_C PF02803.13 OAJ29542.1 - 1.9e-11 43.4 0.7 1.4e-10 40.6 0.2 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 OAJ29542.1 - 2.2e-07 30.1 4.3 5.9e-07 28.7 0.2 2.9 2 1 1 3 3 3 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 OAJ29542.1 - 0.0031 17.1 1.2 0.058 13.0 0.3 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 OAJ29542.1 - 0.011 15.1 4.6 0.15 11.5 1.0 2.4 1 1 1 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 OAJ29542.1 - 0.028 14.2 1.3 0.13 12.1 0.5 2.5 2 1 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain ATP_bind_3 PF01171.15 OAJ29544.1 - 3e-15 56.1 0.0 5.2e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 PP-loop family RecR PF02132.10 OAJ29544.1 - 0.0044 16.4 1.3 0.0044 16.4 0.9 3.0 3 0 0 3 3 3 1 RecR protein tRNA_Me_trans PF03054.11 OAJ29544.1 - 0.078 11.5 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase TF_Zn_Ribbon PF08271.7 OAJ29544.1 - 4 6.8 10.9 1.1 8.6 0.4 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding Het-C PF07217.6 OAJ29545.1 - 6.4e-217 721.5 0.0 1.2e-216 720.6 0.0 1.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF2780 PF11075.3 OAJ29545.1 - 0.0053 16.8 1.9 0.027 14.5 0.6 2.3 2 0 0 2 2 2 1 Protein of unknown function VcgC/VcgE (DUF2780) SSPI PF14098.1 OAJ29545.1 - 0.12 12.2 0.0 3.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Small, acid-soluble spore protein I IDO PF01231.13 OAJ29545.1 - 0.16 10.3 0.0 7.9 4.7 0.0 2.4 2 0 0 2 2 2 0 Indoleamine 2,3-dioxygenase Serglycin PF04360.7 OAJ29546.1 - 0.3 10.7 1.6 0.58 9.8 1.1 1.4 1 0 0 1 1 1 0 Serglycin NAD_binding_1 PF00175.16 OAJ29547.1 - 6.4e-24 84.6 0.0 1.2e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 OAJ29547.1 - 8.3e-19 67.5 0.0 1.8e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 OAJ29547.1 - 3.3e-07 30.3 0.0 2e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 OAJ29547.1 - 0.0017 18.2 0.0 0.013 15.4 0.0 2.4 3 0 0 3 3 3 1 Siderophore-interacting FAD-binding domain PI3_PI4_kinase PF00454.22 OAJ29548.1 - 1e-46 159.3 0.0 2e-46 158.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 OAJ29548.1 - 3.4e-27 95.0 1.4 6.1e-27 94.2 0.2 2.1 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 OAJ29548.1 - 3.7e-07 29.4 0.0 9.1e-07 28.2 0.0 1.7 1 0 0 1 1 1 1 FATC domain DUF971 PF06155.7 OAJ29548.1 - 0.03 14.7 0.0 0.092 13.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF971) DUF2408 PF10303.4 OAJ29550.1 - 2.5e-52 176.5 0.2 3.2e-35 121.1 0.0 4.8 4 1 1 5 5 5 4 Protein of unknown function (DUF2408) PBP1_TM PF14812.1 OAJ29550.1 - 3.9 7.8 9.7 7.9 6.8 6.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.8 OAJ29550.1 - 8.9 5.8 11.8 21 4.6 8.2 1.6 1 0 0 1 1 1 0 YL1 nuclear protein Aminotran_1_2 PF00155.16 OAJ29551.1 - 5.4e-34 117.7 0.0 6.6e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II IF-2B PF01008.12 OAJ29552.1 - 6.1e-66 222.2 0.0 8.7e-66 221.7 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Methyltransf_23 PF13489.1 OAJ29553.1 - 1.5e-11 44.2 0.0 3.2e-11 43.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ29553.1 - 3.3e-10 40.3 0.0 1.1e-09 38.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ29553.1 - 7.1e-09 36.0 0.0 1.4e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ29553.1 - 2.9e-05 23.6 0.0 6.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ29553.1 - 0.0054 17.3 0.0 0.018 15.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ29553.1 - 0.018 15.3 0.0 0.041 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 OAJ29554.1 - 2.1e-09 36.9 4.9 0.00011 21.8 0.1 6.8 7 0 0 7 7 7 2 WD domain, G-beta repeat Sigma70_ner PF04546.8 OAJ29554.1 - 0.63 9.6 2.7 2.2 7.8 1.0 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region FAM176 PF14851.1 OAJ29554.1 - 4.3 6.9 4.5 4.9 6.8 0.7 2.4 2 0 0 2 2 2 0 FAM176 family Shugoshin_C PF07557.6 OAJ29555.1 - 9.2e-21 72.9 23.8 4.1e-11 42.1 3.4 4.1 3 0 0 3 3 3 3 Shugoshin C terminus Vac_ImportDeg PF09783.4 OAJ29557.1 - 1e-52 178.2 0.0 9.1e-49 165.3 0.0 2.2 2 0 0 2 2 2 2 Vacuolar import and degradation protein FAD_binding_4 PF01565.18 OAJ29558.1 - 1.3e-17 63.6 0.9 3.3e-17 62.2 0.6 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAJ29558.1 - 3.9e-12 45.8 0.3 9.7e-12 44.6 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 OAJ29558.1 - 0.045 12.9 0.0 0.097 11.7 0.0 1.5 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Slx4 PF09494.5 OAJ29559.1 - 4e-08 32.8 0.0 2.3e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Slx4 endonuclease Sigma70_ner PF04546.8 OAJ29559.1 - 0.85 9.1 12.5 3 7.3 2.2 3.2 3 0 0 3 3 3 0 Sigma-70, non-essential region Nop14 PF04147.7 OAJ29559.1 - 7.1 4.4 17.9 0.29 9.0 8.3 1.6 2 0 0 2 2 2 0 Nop14-like family Mago-bind PF09282.5 OAJ29560.1 - 9.5e-12 44.2 2.4 9.5e-12 44.2 1.6 1.9 2 0 0 2 2 2 1 Mago binding CAF1-p150_C2 PF15539.1 OAJ29560.1 - 0.033 13.3 1.3 0.057 12.5 0.9 1.4 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term DUF605 PF04652.11 OAJ29560.1 - 0.066 12.6 15.5 0.075 12.4 10.7 1.1 1 0 0 1 1 1 0 Vta1 like BSP_II PF05432.6 OAJ29560.1 - 0.12 11.6 5.9 0.19 11.0 4.1 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Med3 PF11593.3 OAJ29560.1 - 0.14 11.3 19.0 0.034 13.3 8.4 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal PBP1_TM PF14812.1 OAJ29560.1 - 0.49 10.7 3.9 1.4 9.2 2.7 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 OAJ29560.1 - 1.8 6.3 7.0 2.1 6.1 4.9 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 OAJ29560.1 - 6.1 6.0 5.8 8.6 5.5 4.0 1.1 1 0 0 1 1 1 0 NOA36 protein ABC1 PF03109.11 OAJ29561.1 - 4.9e-18 65.2 0.1 2.3e-08 34.0 0.0 2.7 2 0 0 2 2 2 2 ABC1 family FA_desaturase PF00487.19 OAJ29562.1 - 6.7e-33 114.2 17.3 3.5e-32 111.8 12.0 2.2 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 OAJ29562.1 - 1.3e-08 34.4 0.0 4.6e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain CMAS PF02353.15 OAJ29563.1 - 3.2e-62 210.1 0.1 3.9e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 OAJ29563.1 - 4.3e-15 55.7 0.0 8.5e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ29563.1 - 1.7e-09 38.0 0.0 5.6e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ29563.1 - 8.2e-08 32.5 0.0 1.6e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ29563.1 - 1.6e-07 31.8 0.0 3.3e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ29563.1 - 3.3e-07 30.3 0.1 1.2e-06 28.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ29563.1 - 3.2e-06 26.7 0.0 5.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ29563.1 - 1.1e-05 25.8 0.0 2.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 OAJ29563.1 - 0.00015 21.1 0.0 0.00038 19.8 0.0 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 PCMT PF01135.14 OAJ29563.1 - 0.0008 19.0 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 OAJ29563.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 OAJ29563.1 - 0.0074 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 OAJ29563.1 - 0.15 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Ribosomal_S4e PF00900.15 OAJ29564.1 - 1e-29 102.0 0.6 2.1e-29 100.9 0.1 1.8 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 OAJ29564.1 - 7.1e-20 70.5 3.6 1.3e-19 69.7 2.5 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.24 OAJ29564.1 - 0.00027 20.5 1.0 0.0008 19.0 0.7 1.9 1 0 0 1 1 1 1 KOW motif S4 PF01479.20 OAJ29564.1 - 0.0075 15.6 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 S4 domain Chitin_synth_1 PF01644.12 OAJ29566.1 - 8.3e-67 224.0 0.0 1.3e-66 223.3 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 OAJ29566.1 - 1.4e-25 88.7 0.0 2.5e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 OAJ29566.1 - 6e-24 84.3 3.0 5.5e-17 61.3 0.0 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 OAJ29566.1 - 4.6e-11 42.7 7.8 4.7e-11 42.7 0.1 2.4 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ29566.1 - 4e-05 23.5 0.0 7.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 YhjQ PF06564.7 OAJ29566.1 - 0.081 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 YhjQ protein NTP_transferase PF00483.18 OAJ29567.1 - 2.2e-05 23.8 0.0 3.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Fes1 PF08609.5 OAJ29569.1 - 1.6e-16 60.5 0.8 1.5e-14 54.1 0.3 3.0 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT PF02985.17 OAJ29569.1 - 6.1e-05 22.7 2.4 0.83 9.8 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 OAJ29569.1 - 0.00013 22.2 0.8 0.065 13.5 0.0 4.0 3 0 0 3 3 3 1 HEAT repeats Adaptin_N PF01602.15 OAJ29569.1 - 0.014 13.7 0.0 0.99 7.6 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.1 OAJ29569.1 - 3.7 8.1 9.1 22 5.7 0.0 4.6 5 0 0 5 5 5 0 HEAT-like repeat PMT PF02366.13 OAJ29570.1 - 7.6e-72 241.6 12.6 7.6e-72 241.6 8.8 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 OAJ29570.1 - 5.6e-41 140.1 0.0 1.4e-40 138.8 0.0 1.7 1 0 0 1 1 1 1 MIR domain YfzA PF14118.1 OAJ29571.1 - 0.02 14.9 3.3 0.38 10.8 0.1 2.8 3 0 0 3 3 3 0 YfzA-like protein Thioredoxin PF00085.15 OAJ29572.1 - 9.2e-28 95.9 0.0 1.2e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 OAJ29572.1 - 6.4e-08 32.6 0.1 1.5e-05 25.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ29572.1 - 2.1e-07 31.1 0.0 1.1e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 OAJ29572.1 - 1.3e-06 28.3 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 OAJ29572.1 - 0.00011 21.7 0.3 0.0084 15.6 0.1 2.1 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 OAJ29572.1 - 0.00015 21.4 0.1 0.00051 19.7 0.0 1.6 1 1 1 2 2 2 1 AhpC/TSA family DIM1 PF02966.11 OAJ29572.1 - 0.00016 21.1 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_9 PF14595.1 OAJ29572.1 - 0.0011 18.5 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.6 OAJ29572.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE zf-RING_2 PF13639.1 OAJ29573.1 - 4.6e-11 42.3 10.6 2.7e-08 33.4 0.8 3.5 3 1 0 3 3 3 2 Ring finger domain zf-rbx1 PF12678.2 OAJ29573.1 - 3.1e-06 27.2 1.2 3.1e-06 27.2 0.8 2.7 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 OAJ29573.1 - 9.1e-05 22.0 5.5 0.01 15.4 0.5 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ29573.1 - 0.00014 21.4 4.4 0.015 15.0 0.3 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAJ29573.1 - 0.00054 19.5 0.4 0.00054 19.5 0.3 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ29573.1 - 0.00098 19.1 0.8 0.00098 19.1 0.5 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAJ29573.1 - 0.0032 17.2 0.8 0.0032 17.2 0.5 2.6 3 0 0 3 3 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 OAJ29573.1 - 0.44 10.6 5.9 0.22 11.5 1.8 2.3 2 1 0 2 2 2 0 RING-variant domain PHD PF00628.24 OAJ29573.1 - 1.3 8.8 12.1 0.67 9.6 1.5 3.6 4 0 0 4 4 4 0 PHD-finger zf-RING_4 PF14570.1 OAJ29573.1 - 2 8.0 4.6 31 4.2 0.1 3.3 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 OAJ29573.1 - 2.7 8.0 5.1 7.3 6.6 0.1 2.6 2 0 0 2 2 2 0 RING-like domain zf-MIZ PF02891.15 OAJ29573.1 - 5 6.7 9.0 0.44 10.1 1.0 2.8 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger FA_hydroxylase PF04116.8 OAJ29574.1 - 1.6e-09 38.1 11.9 1.6e-09 38.1 8.2 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SPA PF08616.5 OAJ29575.1 - 0.038 13.6 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis Avl9 PF09794.4 OAJ29575.1 - 0.15 10.5 0.0 1.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Transport protein Avl9 ADH_N PF08240.7 OAJ29576.1 - 8.5e-28 96.2 3.5 1.3e-27 95.7 2.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF4241 PF14025.1 OAJ29576.1 - 0.048 13.4 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) Tetraspannin PF00335.15 OAJ29576.1 - 0.12 11.6 0.1 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 Tetraspanin family Arrestin_N PF00339.24 OAJ29577.1 - 0.0036 17.1 0.0 0.0086 15.8 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Ribosomal_L13 PF00572.13 OAJ29578.1 - 1.8e-48 163.7 1.0 2.1e-48 163.5 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 SNARE_assoc PF09335.6 OAJ29580.1 - 1.1e-16 61.0 4.3 1.1e-16 61.0 3.0 2.7 2 1 1 3 3 3 1 SNARE associated Golgi protein FtsX PF02687.16 OAJ29580.1 - 0.53 10.0 12.4 0.62 9.8 0.2 3.3 2 1 1 3 3 3 0 FtsX-like permease family DUF202 PF02656.10 OAJ29580.1 - 4.2 7.6 8.2 2.9 8.1 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Ctr PF04145.10 OAJ29580.1 - 9.1 6.3 7.9 0.57 10.2 0.8 2.4 2 1 0 2 2 2 0 Ctr copper transporter family Ras PF00071.17 OAJ29581.1 - 4.4e-36 123.6 0.1 5e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ29581.1 - 5.5e-11 43.0 0.0 8e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 OAJ29581.1 - 0.0024 17.3 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 OAJ29581.1 - 0.021 14.0 0.0 0.023 13.9 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family FeoB_N PF02421.13 OAJ29581.1 - 0.052 12.8 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B Man-6-P_recep PF02157.10 OAJ29581.1 - 0.064 12.2 0.4 0.14 11.1 0.3 1.6 1 1 0 1 1 1 0 Mannose-6-phosphate receptor Methyltransf_17 PF12692.2 OAJ29582.1 - 0.00041 20.0 0.3 0.0024 17.5 0.1 2.3 2 1 0 2 2 2 1 S-adenosyl-L-methionine methyltransferase Baculo_PEP_C PF04513.7 OAJ29582.1 - 0.0048 16.7 0.4 0.61 9.9 0.1 2.8 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Tannase PF07519.6 OAJ29583.1 - 3.4e-10 39.2 0.4 5.3e-10 38.6 0.3 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase PDGLE PF13190.1 OAJ29584.1 - 0.024 14.2 1.3 0.068 12.8 0.4 2.2 2 0 0 2 2 2 0 PDGLE domain SH3_9 PF14604.1 OAJ29585.1 - 1.5e-22 78.8 0.5 1.8e-13 49.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 OAJ29585.1 - 1.3e-19 69.3 0.0 2.5e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 OAJ29585.1 - 1.6e-15 56.2 0.1 4.4e-09 35.6 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 OAJ29585.1 - 1.3e-13 50.9 0.1 1.4e-12 47.5 0.0 2.8 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.17 OAJ29585.1 - 1.4e-11 43.9 5.2 2.2e-11 43.3 3.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.6 OAJ29585.1 - 0.0012 19.0 1.3 0.0018 18.3 0.2 1.9 2 0 0 2 2 2 1 Bacterial SH3 domain Prominin PF05478.6 OAJ29585.1 - 1.4 6.4 3.6 4.9 4.5 2.5 1.8 1 1 0 1 1 1 0 Prominin MFS_1 PF07690.11 OAJ29586.1 - 2.5e-15 56.0 6.4 1.4e-06 27.3 1.9 3.3 2 1 0 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAJ29586.1 - 1.3e-11 43.5 0.0 7.9e-11 40.9 0.0 2.0 2 1 0 2 2 2 1 MFS/sugar transport protein PBP1_TM PF14812.1 OAJ29586.1 - 0.16 12.3 12.5 0.046 14.0 3.1 3.0 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF788 PF05620.6 OAJ29586.1 - 0.26 11.1 0.0 0.67 9.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Sigma70_ner PF04546.8 OAJ29586.1 - 0.66 9.5 6.5 0.56 9.7 2.3 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Dicty_REP PF05086.7 OAJ29586.1 - 0.82 7.3 1.7 1.3 6.6 1.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4611 PF15387.1 OAJ29586.1 - 1.2 9.3 10.0 2.5 8.3 4.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 OAJ29586.1 - 4.7 6.7 10.4 1.9 8.0 3.6 2.2 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 OAJ29586.1 - 7.6 6.8 16.3 1.9 8.7 6.8 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain EF-hand_7 PF13499.1 OAJ29587.1 - 2.9e-13 49.7 0.0 4e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 OAJ29587.1 - 2.8e-12 45.4 0.2 2.4e-05 23.8 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 OAJ29587.1 - 6.9e-12 43.7 0.1 1.1e-05 24.4 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 OAJ29587.1 - 6e-09 35.7 0.0 3.3e-05 23.7 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 OAJ29587.1 - 4.1e-05 23.1 0.3 0.013 15.1 0.0 3.7 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 OAJ29587.1 - 0.0052 16.0 0.3 0.079 12.3 0.0 2.7 2 0 0 2 2 2 1 EF hand EFhand_Ca_insen PF08726.5 OAJ29587.1 - 0.025 14.5 0.0 0.15 12.0 0.0 2.2 2 1 0 2 2 2 0 Ca2+ insensitive EF hand UPF0154 PF03672.8 OAJ29587.1 - 0.035 13.7 0.0 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) TFIID-18kDa PF02269.11 OAJ29588.1 - 2e-17 62.8 0.1 2.7e-07 30.3 0.2 2.1 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit GLTSCR1 PF15249.1 OAJ29588.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region FAM75 PF14650.1 OAJ29588.1 - 0.38 10.0 5.5 0.52 9.6 3.8 1.1 1 0 0 1 1 1 0 FAM75 family Serglycin PF04360.7 OAJ29588.1 - 7.6 6.2 7.1 1.7 8.3 2.3 1.8 2 0 0 2 2 2 0 Serglycin ThiF PF00899.16 OAJ29589.1 - 8.9e-32 109.7 0.0 1.4e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family Glyco_hydro_17 PF00332.13 OAJ29589.1 - 0.17 10.8 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 TrkA_N PF02254.13 OAJ29589.1 - 0.19 11.6 0.3 0.5 10.3 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Zip PF02535.17 OAJ29589.1 - 4.6 6.1 8.6 0.32 9.9 2.3 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter GTP_cyclohydro2 PF00925.15 OAJ29590.1 - 4e-61 205.1 0.0 2.5e-55 186.2 0.0 2.4 2 0 0 2 2 2 2 GTP cyclohydrolase II PRP21_like_P PF12230.3 OAJ29591.1 - 0.057 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-C3HC4_2 PF13923.1 OAJ29591.1 - 0.23 11.5 11.6 0.39 10.7 8.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_6 PF12697.2 OAJ29592.1 - 4e-24 85.7 0.5 5.3e-24 85.3 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ29592.1 - 7.3e-18 64.7 0.1 2.7e-16 59.6 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 OAJ29592.1 - 4e-10 39.5 0.0 5.2e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 OAJ29592.1 - 1.3e-08 33.7 0.0 5.3e-06 25.1 0.0 2.8 3 0 0 3 3 3 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 OAJ29592.1 - 4.4e-08 32.6 0.0 1.2e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 OAJ29592.1 - 3.6e-07 29.6 0.0 5.6e-06 25.7 0.0 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 OAJ29592.1 - 1.8e-06 27.6 0.0 8.2e-05 22.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 OAJ29592.1 - 7.4e-06 25.8 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 OAJ29592.1 - 0.0002 21.1 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 OAJ29592.1 - 0.00081 18.8 0.1 0.0085 15.5 0.1 2.0 1 1 0 1 1 1 1 Putative esterase Peptidase_S28 PF05577.7 OAJ29592.1 - 0.0019 16.8 0.0 0.0026 16.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 PAF-AH_p_II PF03403.8 OAJ29592.1 - 0.0038 15.5 0.0 1.2 7.3 0.0 2.3 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.8 OAJ29592.1 - 0.0061 16.1 0.3 0.017 14.7 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1100 PF06500.6 OAJ29592.1 - 0.064 11.8 0.0 0.085 11.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_2 PF02230.11 OAJ29592.1 - 0.16 11.3 0.0 17 4.7 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF3678 PF12435.3 OAJ29593.1 - 1.9 8.1 4.5 4.7 6.8 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Se-cys_synth_N PF12390.3 OAJ29593.1 - 3 8.0 5.5 61 3.8 3.2 3.1 1 1 1 2 2 2 0 Selenocysteine synthase N terminal Thioredoxin PF00085.15 OAJ29594.1 - 8.7e-21 73.5 0.0 9.5e-21 73.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 OAJ29594.1 - 7.6e-05 22.7 0.0 0.00055 20.0 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ29594.1 - 0.00071 19.7 0.0 0.0038 17.4 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 OAJ29594.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.3 1 1 0 1 1 1 0 AhpC/TSA family DUF2847 PF11009.3 OAJ29594.1 - 0.026 14.1 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Redoxin PF08534.5 OAJ29594.1 - 0.11 12.0 0.1 2.7 7.5 0.0 2.0 1 1 1 2 2 2 0 Redoxin HyaE PF07449.6 OAJ29594.1 - 0.12 12.2 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE OTU PF02338.14 OAJ29595.1 - 1.1e-10 42.0 0.0 2.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease DUF2360 PF10152.4 OAJ29595.1 - 0.065 13.5 1.5 0.11 12.7 1.1 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 OAJ29595.1 - 0.54 9.6 8.7 0.7 9.2 6.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF4106 PF13388.1 OAJ29595.1 - 0.88 8.4 4.8 1.6 7.5 3.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) NDK PF00334.14 OAJ29596.1 - 2.4e-29 101.8 0.0 2.9e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Reo_sigmaC PF04582.7 OAJ29597.1 - 0.03 13.4 5.1 1.2 8.1 1.5 2.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 OAJ29597.1 - 0.37 10.5 38.3 0.58 9.9 5.6 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF869 PF05911.6 OAJ29597.1 - 1.3 7.2 35.1 0.092 10.9 17.1 2.9 2 1 0 2 2 2 0 Plant protein of unknown function (DUF869) FUSC PF04632.7 OAJ29597.1 - 1.7 6.9 12.7 0.45 8.8 5.8 2.1 1 1 0 1 1 1 0 Fusaric acid resistance protein family COesterase PF00135.23 OAJ29598.1 - 5.5e-77 259.6 0.0 7.6e-77 259.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ29598.1 - 1.2e-08 34.8 1.6 2.3e-05 24.1 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Exo_endo_phos PF03372.18 OAJ29599.1 - 6e-18 65.6 0.0 8.9e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 OAJ29599.1 - 0.0055 16.3 0.0 0.048 13.2 0.0 2.2 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Adeno_VII PF03228.9 OAJ29599.1 - 0.25 11.9 0.0 0.25 11.9 0.0 2.8 2 1 1 3 3 3 0 Adenoviral core protein VII AAA PF00004.24 OAJ29600.1 - 1.1e-13 51.5 0.0 2.3e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 OAJ29600.1 - 4.5e-08 32.2 0.0 0.0028 16.3 0.0 2.9 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 OAJ29600.1 - 2.4e-05 24.2 0.0 4.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ29600.1 - 2.5e-05 23.9 0.0 0.0001 21.9 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 OAJ29600.1 - 7.5e-05 21.8 0.0 0.00015 20.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 OAJ29600.1 - 0.00017 21.6 0.1 0.036 14.0 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 OAJ29600.1 - 0.00018 21.4 0.0 0.00037 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 OAJ29600.1 - 0.00042 21.1 0.0 0.0013 19.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ29600.1 - 0.0038 17.3 0.0 0.014 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 OAJ29600.1 - 0.011 15.7 0.1 0.03 14.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 OAJ29600.1 - 0.021 14.6 0.1 0.08 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 OAJ29600.1 - 0.028 14.1 0.1 0.13 12.0 0.0 2.0 1 1 1 2 2 2 0 NTPase NACHT PF05729.7 OAJ29600.1 - 0.045 13.4 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 OAJ29600.1 - 0.052 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 OAJ29600.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 OAJ29600.1 - 0.067 13.4 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 OAJ29600.1 - 0.076 12.4 0.0 0.25 10.7 0.0 1.8 1 1 1 2 2 2 0 AAA-like domain Membr_traf_MHD PF10540.4 OAJ29600.1 - 0.12 12.1 0.0 0.34 10.7 0.0 1.7 2 0 0 2 2 1 0 Munc13 (mammalian uncoordinated) homology domain KaiC PF06745.8 OAJ29600.1 - 0.25 10.4 0.0 0.55 9.3 0.0 1.4 1 0 0 1 1 1 0 KaiC Tcf25 PF04910.9 OAJ29601.1 - 6.6e-78 262.1 0.0 9.5e-78 261.6 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 XPC-binding PF09280.6 OAJ29601.1 - 0.025 14.0 1.0 1.2 8.6 0.0 2.7 2 0 0 2 2 2 0 XPC-binding domain TPR_12 PF13424.1 OAJ29601.1 - 0.049 13.5 0.8 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TATR PF03430.8 OAJ29601.1 - 1.3 7.5 2.1 2 6.9 1.5 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator RNase_H2-Ydr279 PF09468.5 OAJ29601.1 - 1.5 7.9 5.7 2.7 7.1 4.0 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Spt20 PF12090.3 OAJ29602.1 - 1.2e-34 119.2 0.0 1.2e-34 119.2 0.0 5.5 4 2 0 4 4 4 1 Spt20 family OmpH PF03938.9 OAJ29602.1 - 0.0032 17.4 11.1 0.0032 17.4 7.7 3.7 3 1 0 3 3 3 2 Outer membrane protein (OmpH-like) AAA_23 PF13476.1 OAJ29602.1 - 0.011 16.0 9.6 0.011 16.0 6.7 3.4 3 0 0 3 3 3 0 AAA domain DUF221 PF02714.10 OAJ29604.1 - 3.5e-84 282.4 17.3 5.1e-84 281.8 12.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAJ29604.1 - 9.5e-25 86.9 0.1 9.5e-25 86.9 0.1 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 OAJ29604.1 - 1.9e-08 34.6 0.1 4.4e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF4611 PF15387.1 OAJ29604.1 - 2 8.5 7.0 5.9 7.0 3.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Tetraspannin PF00335.15 OAJ29605.1 - 7.3e-10 38.5 14.0 1.3e-09 37.6 9.7 1.3 1 0 0 1 1 1 1 Tetraspanin family DUF2104 PF09877.4 OAJ29605.1 - 0.07 13.0 0.6 0.14 12.1 0.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2104) FA_desaturase PF00487.19 OAJ29605.1 - 0.48 9.8 2.7 0.96 8.8 1.9 1.4 1 0 0 1 1 1 0 Fatty acid desaturase Prefoldin_2 PF01920.15 OAJ29606.1 - 4.1e-18 65.0 0.3 5.7e-18 64.6 0.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF812 PF05667.6 OAJ29606.1 - 0.0024 16.4 1.0 0.0028 16.2 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Golgin_A5 PF09787.4 OAJ29606.1 - 0.0041 15.7 1.0 0.0044 15.6 0.7 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF641 PF04859.7 OAJ29606.1 - 0.087 12.5 2.1 0.63 9.7 0.6 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF3166 PF11365.3 OAJ29606.1 - 0.095 13.1 0.7 4.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) Prefoldin PF02996.12 OAJ29606.1 - 0.15 11.7 0.9 0.96 9.1 0.6 2.0 1 1 0 1 1 1 0 Prefoldin subunit Psu PF07455.6 OAJ29606.1 - 0.28 10.6 3.1 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Phage polarity suppression protein (Psu) DUF4407 PF14362.1 OAJ29606.1 - 0.57 9.0 4.6 0.82 8.5 3.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Daxx PF03344.10 OAJ29607.1 - 0.023 13.2 9.6 0.033 12.6 6.7 1.2 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 OAJ29607.1 - 0.18 10.4 14.0 0.28 9.8 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIF_alpha PF05793.7 OAJ29607.1 - 0.21 9.9 8.8 0.31 9.3 6.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 OAJ29607.1 - 0.25 9.2 9.4 0.31 8.9 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family Herpes_LMP1 PF05297.6 OAJ29607.1 - 0.39 9.5 3.8 0.69 8.7 2.7 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) EBV-NA3 PF05009.7 OAJ29607.1 - 1.5 8.0 5.4 2.5 7.2 3.8 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RRN3 PF05327.6 OAJ29607.1 - 2.4 6.1 4.2 3.1 5.8 2.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.7 OAJ29607.1 - 3.3 6.9 12.7 4.5 6.4 8.8 1.1 1 0 0 1 1 1 0 SDA1 Menin PF05053.8 OAJ29607.1 - 3.8 5.5 9.0 5.6 5.0 6.2 1.3 1 0 0 1 1 1 0 Menin NOA36 PF06524.7 OAJ29607.1 - 4.8 6.3 7.7 7 5.8 5.3 1.1 1 0 0 1 1 1 0 NOA36 protein EF-hand_4 PF12763.2 OAJ29608.1 - 8e-33 112.2 0.0 3.1e-14 52.5 0.0 3.3 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 OAJ29608.1 - 1.7e-06 27.6 0.0 4.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.1 OAJ29608.1 - 4.1e-06 26.8 0.0 0.0074 16.3 0.0 3.6 3 1 1 4 4 4 2 EF-hand domain pair FliJ PF02050.11 OAJ29608.1 - 0.095 12.7 3.8 0.08 12.9 0.9 2.0 1 1 1 2 2 2 0 Flagellar FliJ protein Reo_sigmaC PF04582.7 OAJ29608.1 - 0.098 11.8 6.0 0.29 10.2 0.2 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ATG16 PF08614.6 OAJ29608.1 - 0.15 11.8 10.0 0.74 9.6 7.0 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) EzrA PF06160.7 OAJ29608.1 - 0.2 9.8 2.5 0.3 9.2 1.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF812 PF05667.6 OAJ29608.1 - 0.23 9.8 8.1 0.35 9.3 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4201 PF13870.1 OAJ29608.1 - 0.9 8.9 4.1 1.9 7.8 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Spc7 PF08317.6 OAJ29608.1 - 1.1 7.8 5.8 1.8 7.1 4.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2570 PF10828.3 OAJ29608.1 - 1.3 8.6 2.4 2.6 7.6 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) CENP-F_leu_zip PF10473.4 OAJ29608.1 - 2.8 7.8 17.1 1.1 9.0 6.8 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 OAJ29608.1 - 2.9 6.2 3.4 4.2 5.7 2.4 1.1 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.7 OAJ29608.1 - 3 7.5 10.2 9.4 5.9 7.0 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.10 OAJ29608.1 - 6 6.8 14.9 13 5.7 10.3 1.4 1 1 0 1 1 1 0 Fez1 CENP-Q PF13094.1 OAJ29608.1 - 6.5 6.7 11.4 6.2 6.8 6.6 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Histone PF00125.19 OAJ29609.1 - 6.2e-20 71.0 0.0 9.8e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAJ29609.1 - 7.9e-06 25.8 0.0 1.8e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HCMVantigenic_N PF12154.3 OAJ29609.1 - 0.13 12.1 1.2 0.25 11.2 0.8 1.4 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV GATase_2 PF00310.16 OAJ29610.1 - 2.3e-24 85.8 0.1 6.1e-19 67.9 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 OAJ29610.1 - 2.3e-16 59.9 0.0 5.3e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 OAJ29610.1 - 4e-14 52.4 0.5 7.5e-14 51.5 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 OAJ29610.1 - 1.6e-12 47.2 0.0 3.2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 OAJ29610.1 - 6.6e-07 28.2 0.0 1.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DnaJ PF00226.26 OAJ29611.1 - 1.5e-21 75.9 2.4 1.6e-21 75.8 0.2 2.3 2 0 0 2 2 2 1 DnaJ domain DUF1843 PF08898.5 OAJ29611.1 - 0.044 13.8 1.7 0.54 10.3 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) RPT PF13446.1 OAJ29611.1 - 0.058 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein DUF221 PF02714.10 OAJ29612.1 - 6e-95 317.8 21.8 9.1e-95 317.2 15.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAJ29612.1 - 7.7e-37 126.2 2.0 2.4e-36 124.6 1.4 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 OAJ29612.1 - 1.8e-20 73.2 3.8 2.9e-20 72.5 2.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 OAJ29612.1 - 2e-13 50.0 0.0 5.8e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein Cyanate_lyase PF02560.9 OAJ29613.1 - 4.3e-35 119.0 0.0 6.3e-35 118.5 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 OAJ29613.1 - 0.00044 20.4 0.0 0.00069 19.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 OAJ29613.1 - 0.0029 17.6 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 OAJ29613.1 - 0.014 15.1 0.0 0.036 13.9 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix KorB PF08535.5 OAJ29613.1 - 0.066 13.3 0.0 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 KorB domain HTH_38 PF13936.1 OAJ29613.1 - 0.091 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Chitin_synth_1 PF01644.12 OAJ29614.1 - 4.5e-33 114.3 0.0 9e-29 100.3 0.0 2.5 2 1 0 2 2 2 2 Chitin synthase Chitin_synth_2 PF03142.10 OAJ29614.1 - 4.9e-12 45.0 0.0 1e-06 27.4 0.0 3.0 2 1 1 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.6 OAJ29614.1 - 3.6e-10 39.3 0.8 6.6e-10 38.5 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Sugar_tr PF00083.19 OAJ29615.1 - 4.7e-121 404.5 30.7 5.4e-121 404.3 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ29615.1 - 3.5e-20 72.0 46.5 9.6e-18 64.0 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DEADboxA PF12343.3 OAJ29615.1 - 0.11 12.7 0.2 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Cold shock protein DEAD box A tRNA-synt_1 PF00133.17 OAJ29616.1 - 1.6e-209 696.8 0.0 1.4e-208 693.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 OAJ29616.1 - 4.1e-36 124.0 0.2 8.4e-36 123.0 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 OAJ29616.1 - 6.4e-19 67.8 0.3 1.2e-09 37.3 0.1 4.9 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 OAJ29616.1 - 7.5e-08 31.8 5.8 4.7e-06 26.0 0.0 2.9 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 OAJ29616.1 - 0.0008 18.6 0.0 0.49 9.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 OAJ29616.1 - 0.0016 17.3 0.0 0.034 12.9 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1c PF00749.16 OAJ29616.1 - 0.027 13.1 0.5 2.4 6.7 0.0 3.5 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain ATG11 PF10377.4 OAJ29616.1 - 0.14 12.0 1.7 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Autophagy-related protein 11 Aldo_ket_red PF00248.16 OAJ29617.1 - 3.7e-53 180.2 0.0 4.4e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ECH PF00378.15 OAJ29618.1 - 1.9e-18 66.5 0.0 2.2e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family UPF0147 PF03685.8 OAJ29619.1 - 0.072 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) F-box-like PF12937.2 OAJ29619.1 - 0.095 12.4 0.2 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 F-box-like ECH PF00378.15 OAJ29620.1 - 3e-19 69.1 0.0 4.1e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Na_Ca_ex PF01699.19 OAJ29621.1 - 1.7e-18 66.5 24.8 8.3e-13 48.1 4.5 2.8 3 1 0 3 3 3 2 Sodium/calcium exchanger protein HUN PF08729.5 OAJ29622.1 - 5.6e-10 38.9 0.1 5.6e-10 38.9 0.1 2.4 2 0 0 2 2 2 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 OAJ29622.1 - 0.0091 15.6 0.1 0.0091 15.6 0.0 3.6 4 0 0 4 4 4 1 Ubinuclein conserved middle domain Nop14 PF04147.7 OAJ29622.1 - 4.9 4.9 15.6 0.19 9.5 4.8 2.1 2 0 0 2 2 2 0 Nop14-like family MTHFR PF02219.12 OAJ29623.1 - 3.7e-94 315.0 0.0 4.1e-84 282.0 0.0 3.3 3 0 0 3 3 3 3 Methylenetetrahydrofolate reductase Ala_racemase_N PF01168.15 OAJ29623.1 - 1.5e-26 93.3 1.6 2.5e-24 86.0 1.1 2.5 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Cytochrom_B561 PF03188.11 OAJ29623.1 - 3.7e-08 33.3 13.0 7.2e-08 32.3 9.0 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Spt20 PF12090.3 OAJ29624.1 - 1.1 8.6 8.2 1.1 8.5 1.2 2.5 2 0 0 2 2 2 0 Spt20 family Cut8_N PF14482.1 OAJ29625.1 - 0.0015 18.4 2.1 0.0015 18.4 1.5 3.0 3 2 0 3 3 3 1 Cut8 proteasome-binding domain DUF3474 PF11960.3 OAJ29625.1 - 0.33 10.9 2.6 0.64 10.0 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Zip PF02535.17 OAJ29625.1 - 1.5 7.7 14.1 2.6 6.9 9.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter HGTP_anticodon2 PF12745.2 OAJ29625.1 - 2.1 7.4 6.2 3 6.9 4.3 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Myb_DNA-binding PF00249.26 OAJ29626.1 - 3.1e-26 91.1 4.0 5.9e-09 35.8 0.6 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ29626.1 - 1.3e-25 89.2 4.2 7.3e-11 42.0 0.0 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain BRF1 PF07741.8 OAJ29626.1 - 1.1 9.5 6.5 6.8 6.9 1.4 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain AvrE PF11725.3 OAJ29626.1 - 9.2 3.1 19.3 12 2.6 13.4 1.1 1 0 0 1 1 1 0 Pathogenicity factor Myb_DNA-binding PF00249.26 OAJ29627.1 - 6.7e-28 96.4 4.7 3.8e-09 36.4 0.0 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ29627.1 - 3.4e-26 91.1 4.9 1.8e-10 40.7 0.0 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 OAJ29627.1 - 0.00043 20.0 3.8 0.5 10.1 0.1 3.0 2 1 0 2 2 2 2 Rap1 Myb domain CDK5_activator PF03261.10 OAJ29627.1 - 0.0071 15.7 5.4 0.0097 15.2 3.7 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 5 activator protein DUF2413 PF10310.4 OAJ29627.1 - 0.23 10.2 8.3 0.33 9.6 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Det1 PF09737.4 OAJ29627.1 - 0.44 9.2 2.4 0.64 8.7 1.7 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 MADF_DNA_bdg PF10545.4 OAJ29627.1 - 1 9.5 7.4 4.8 7.4 0.1 3.1 3 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.1 OAJ29627.1 - 4.4 7.2 9.5 16 5.4 0.6 3.9 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain DUF572 PF04502.8 OAJ29628.1 - 2.5e-88 296.4 0.1 3.3e-88 296.0 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) COG5 PF10392.4 OAJ29628.1 - 0.041 13.8 0.6 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 HrpA_pilin PF09589.5 OAJ29628.1 - 0.095 13.1 0.2 0.095 13.1 0.1 2.1 2 1 0 2 2 2 0 HrpA pilus formation protein DUF866 PF05907.8 OAJ29628.1 - 0.13 11.7 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Benyvirus_14KDa PF07255.6 OAJ29628.1 - 0.14 12.0 0.2 0.35 10.7 0.1 1.6 1 1 0 1 1 1 0 Benyvirus 14KDa protein Lar_restr_allev PF14354.1 OAJ29628.1 - 0.18 12.0 0.9 2.7 8.3 0.6 2.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF2365 PF10157.4 OAJ29628.1 - 0.24 11.2 1.6 12 5.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) Mito_carr PF00153.22 OAJ29629.1 - 3.4e-69 228.6 0.9 5.4e-24 83.7 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein DOR PF14839.1 OAJ29629.1 - 0.014 15.1 5.8 0.014 15.1 4.0 2.5 3 0 0 3 3 3 0 DOR family TFIIA PF03153.8 OAJ29629.1 - 2.6 7.8 12.8 4.3 7.1 8.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM196 PF15265.1 OAJ29629.1 - 5.6 6.0 13.3 8.4 5.5 9.2 1.1 1 0 0 1 1 1 0 FAM196 family peroxidase PF00141.18 OAJ29630.1 - 8.2e-49 166.1 0.0 1.5e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Syntaxin-18_N PF10496.4 OAJ29631.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus SnoaL PF07366.7 OAJ29631.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 OAJ29631.1 - 0.15 12.4 0.0 0.17 12.3 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain PASTA PF03793.14 OAJ29633.1 - 0.074 12.7 2.9 0.08 12.6 0.5 2.2 2 0 0 2 2 2 0 PASTA domain ATP-synt_DE PF00401.15 OAJ29633.1 - 1 9.3 8.0 6.9 6.6 0.8 2.9 2 1 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DnaJ PF00226.26 OAJ29634.1 - 2.8e-15 55.7 1.8 6.6e-15 54.5 1.3 1.7 1 0 0 1 1 1 1 DnaJ domain XdhC_CoxI PF02625.11 OAJ29634.1 - 0.13 11.9 0.1 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 XdhC and CoxI family DUF1279 PF06916.8 OAJ29636.1 - 4e-16 59.0 0.3 4.6e-15 55.7 0.2 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Peptidase_S8 PF00082.17 OAJ29637.1 - 8.8e-51 172.7 0.0 1.3e-50 172.1 0.0 1.3 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 OAJ29637.1 - 1.1e-05 25.8 0.0 1.9e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 OAJ29637.1 - 3.9e-05 23.2 0.0 0.00014 21.5 0.0 2.0 1 0 0 1 1 1 1 PA domain Urb2 PF10441.4 OAJ29638.1 - 8.5e-30 104.0 0.0 6e-29 101.2 0.0 2.7 2 0 0 2 2 2 1 Urb2/Npa2 family F-box-like PF12937.2 OAJ29639.1 - 1.5e-07 31.0 0.5 9e-07 28.5 0.5 2.4 2 0 0 2 2 2 1 F-box-like TPR_11 PF13414.1 OAJ29639.1 - 0.012 15.2 1.2 0.049 13.2 0.5 2.1 1 1 2 3 3 3 0 TPR repeat F-box PF00646.28 OAJ29639.1 - 0.013 15.1 0.6 0.048 13.3 0.4 2.0 1 1 0 1 1 1 0 F-box domain DMRL_synthase PF00885.14 OAJ29640.1 - 4.6e-43 146.3 0.0 7.1e-24 84.1 0.0 2.1 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase BaffR-Tall_bind PF09256.5 OAJ29640.1 - 0.051 13.1 0.1 0.051 13.1 0.0 2.0 2 0 0 2 2 2 0 BAFF-R, TALL-1 binding Sld5 PF05916.6 OAJ29641.1 - 0.0045 17.2 0.0 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Peptidase_M17 PF00883.16 OAJ29641.1 - 0.12 11.1 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 Cytosol aminopeptidase family, catalytic domain Transcrip_reg PF01709.15 OAJ29642.1 - 3.9e-54 183.2 0.0 1.5e-53 181.3 0.0 1.7 1 1 1 2 2 2 1 Transcriptional regulator Spore_III_AB PF09548.5 OAJ29642.1 - 0.01 15.6 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) Adaptin_N PF01602.15 OAJ29643.1 - 3.1e-139 464.6 2.0 3.9e-139 464.3 1.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 OAJ29643.1 - 1e-25 90.5 1.9 6.9e-24 84.6 0.1 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 OAJ29643.1 - 2.3e-16 59.8 8.6 1.8e-09 37.7 0.1 4.9 1 1 3 5 5 5 3 HEAT repeats HEAT PF02985.17 OAJ29643.1 - 3.1e-09 36.1 4.4 0.0047 16.8 0.0 5.4 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.18 OAJ29643.1 - 1.7e-06 27.5 3.2 0.0051 16.5 0.0 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 OAJ29643.1 - 6.6e-05 23.2 6.9 0.52 10.8 0.1 5.8 6 1 1 7 7 7 2 HEAT-like repeat Cnd3 PF12719.2 OAJ29643.1 - 9.2e-05 21.5 0.0 0.0076 15.2 0.0 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Arm_2 PF04826.8 OAJ29643.1 - 0.0011 18.1 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 Armadillo-like Atx10homo_assoc PF09759.4 OAJ29643.1 - 0.099 12.3 0.0 3.1 7.5 0.0 3.0 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 OAJ29643.1 - 0.19 11.0 4.4 5.7 6.2 0.0 3.5 4 1 1 5 5 5 0 CLASP N terminal HAMP PF00672.20 OAJ29644.1 - 8.2e-46 154.0 19.6 1.1e-07 31.8 0.1 8.0 7 0 0 7 7 7 7 HAMP domain Response_reg PF00072.19 OAJ29644.1 - 5.5e-27 93.9 0.7 1.2e-24 86.4 0.3 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 OAJ29644.1 - 5.9e-27 93.5 0.0 2e-26 91.8 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 OAJ29644.1 - 6e-17 61.3 0.3 4.7e-16 58.5 0.2 2.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pox_A_type_inc PF04508.7 OAJ29644.1 - 0.067 13.0 0.2 0.97 9.3 0.0 3.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PMC2NT PF08066.7 OAJ29644.1 - 0.36 11.1 5.3 3.7 7.9 0.0 4.2 4 0 0 4 4 4 0 PMC2NT (NUC016) domain Syntaxin PF00804.20 OAJ29644.1 - 1.7 8.8 6.7 16 5.7 1.2 4.5 3 2 0 3 3 3 0 Syntaxin Proteasome PF00227.21 OAJ29645.1 - 1.7e-31 108.9 0.0 2.1e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit TFIID-18kDa PF02269.11 OAJ29646.1 - 6.2e-32 109.2 0.5 1.7e-30 104.6 0.5 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit NAM-associated PF14303.1 OAJ29647.1 - 0.22 11.8 18.7 0.027 14.7 9.5 1.9 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Nucleoplasmin PF03066.10 OAJ29647.1 - 8.7 5.8 11.4 0.11 11.9 2.7 1.7 2 0 0 2 2 2 0 Nucleoplasmin DDE_Tnp_4 PF13359.1 OAJ29648.1 - 8.6e-18 64.4 0.0 1.6e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease RyR PF02026.11 OAJ29648.1 - 0.0019 18.1 0.7 0.0089 16.0 0.2 2.3 2 0 0 2 2 2 1 RyR domain Toprim_C_rpt PF13368.1 OAJ29648.1 - 0.14 12.7 0.0 0.46 11.0 0.0 1.9 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat MFS_1 PF07690.11 OAJ29649.1 - 0.00017 20.4 2.6 0.00022 20.0 1.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4202 PF13875.1 OAJ29650.1 - 1.7e-54 184.2 0.0 2.9e-54 183.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Methyltransf_12 PF08242.7 OAJ29650.1 - 1.1e-14 54.7 0.0 1e-12 48.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ29650.1 - 1.2e-13 51.0 0.0 3.2e-12 46.4 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ29650.1 - 4e-09 36.8 0.0 2.9e-07 30.8 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ29650.1 - 2.8e-08 33.4 0.0 1.2e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ29650.1 - 3.5e-08 33.7 0.0 1.1e-07 32.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ29650.1 - 7.3e-07 29.7 0.0 2.6e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 OAJ29650.1 - 0.00039 19.8 0.0 0.00068 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 OAJ29650.1 - 0.0014 18.6 0.0 0.0052 16.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 OAJ29650.1 - 0.015 16.0 0.1 0.1 13.4 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain DUF2422 PF10337.4 OAJ29651.1 - 4.8e-91 305.8 0.1 9.4e-89 298.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 OAJ29651.1 - 7.4e-27 94.4 0.0 2.3e-26 92.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 OAJ29651.1 - 3e-08 33.6 18.6 3e-08 33.6 12.9 3.7 2 1 1 3 3 3 1 Fusaric acid resistance protein-like DUF1180 PF06679.7 OAJ29651.1 - 0.0059 16.5 3.5 1.6 8.6 0.0 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1180) 4HBT PF03061.17 OAJ29653.1 - 2.7e-17 62.6 1.7 1.2e-11 44.5 0.1 3.0 3 1 1 4 4 4 2 Thioesterase superfamily SQS_PSY PF00494.14 OAJ29654.1 - 2e-49 168.3 0.6 6.3e-49 166.6 0.4 1.9 1 1 0 1 1 1 1 Squalene/phytoene synthase Saccharop_dh PF03435.13 OAJ29655.1 - 1.1e-104 350.4 0.0 1.8e-104 349.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 OAJ29655.1 - 3.2e-85 284.9 0.0 5.7e-85 284.1 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase Semialdhyde_dh PF01118.19 OAJ29655.1 - 0.00029 21.1 0.2 0.0011 19.2 0.1 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 OAJ29655.1 - 0.00096 19.2 0.3 0.0035 17.3 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding WES_acyltransf PF03007.11 OAJ29658.1 - 2e-15 57.0 0.8 3.2e-15 56.4 0.0 1.8 2 1 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain ACPS PF01648.15 OAJ29659.1 - 1e-08 35.0 0.0 1.6e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Peptidase_C41 PF05417.6 OAJ29659.1 - 0.046 13.2 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Hepatitis E cysteine protease SR-25 PF10500.4 OAJ29659.1 - 0.12 11.8 6.3 0.18 11.2 4.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Helicase_C_2 PF13307.1 OAJ29660.1 - 3.2e-13 49.9 0.0 9.3e-07 28.9 0.0 3.3 2 1 1 3 3 3 3 Helicase C-terminal domain RRM_1 PF00076.17 OAJ29661.1 - 2.9e-27 94.0 0.3 2.1e-16 59.2 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ29661.1 - 7.4e-15 54.6 0.0 4.7e-10 39.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ29661.1 - 3.3e-12 46.0 0.0 4.9e-10 39.1 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ29661.1 - 0.0001 22.1 0.0 0.0001 22.1 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 OAJ29661.1 - 0.0015 18.2 0.0 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Cellulose_synt PF03552.9 OAJ29661.1 - 5.1 5.2 5.4 7.6 4.6 3.7 1.1 1 0 0 1 1 1 0 Cellulose synthase Suf PF05843.9 OAJ29661.1 - 9.5 5.8 26.2 7.2 6.2 11.7 2.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Cellulase PF00150.13 OAJ29662.1 - 0.028 13.6 0.0 0.032 13.4 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) He_PIG PF05345.7 OAJ29663.1 - 5.9e-14 51.8 11.5 1.8e-05 24.6 0.1 4.2 3 0 0 3 3 3 3 Putative Ig domain tRNA-synt_2b PF00587.20 OAJ29664.1 - 1.3e-07 31.4 0.0 1.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Actin PF00022.14 OAJ29666.1 - 2.5e-23 82.1 0.0 1.4e-20 73.0 0.0 3.1 3 1 0 3 3 3 3 Actin DNA_binding_1 PF01035.15 OAJ29667.1 - 2.1e-06 27.3 0.0 3.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain ECH PF00378.15 OAJ29668.1 - 1.8e-32 112.3 0.7 1.3e-30 106.3 0.5 2.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Rop-like PF05082.8 OAJ29668.1 - 0.059 12.8 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Rop-like CD24 PF14984.1 OAJ29669.1 - 5.5 6.8 12.9 4.2 7.2 6.4 2.7 3 0 0 3 3 3 0 CD24 protein Nse4_C PF08743.5 OAJ29670.1 - 1.4e-26 92.2 0.1 3.6e-26 91.0 0.1 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 OAJ29670.1 - 8.2e-09 35.1 0.5 1.7e-08 34.1 0.3 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Snf7 PF03357.16 OAJ29671.1 - 1.6e-45 154.5 12.2 1.9e-45 154.3 8.5 1.0 1 0 0 1 1 1 1 Snf7 Mod_r PF07200.8 OAJ29671.1 - 0.004 17.0 7.2 0.0044 16.9 3.6 1.8 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Soyouz_module PF14313.1 OAJ29671.1 - 0.021 14.3 0.1 1.2 8.7 0.0 2.9 3 0 0 3 3 3 0 N-terminal region of Paramyxovirinae phosphoprotein (P) NuA4 PF09340.5 OAJ29671.1 - 0.062 12.9 0.6 0.062 12.9 0.4 2.0 2 1 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DMPK_coil PF08826.5 OAJ29671.1 - 0.089 12.7 0.3 0.089 12.7 0.2 3.6 4 0 0 4 4 4 0 DMPK coiled coil domain like DUF3091 PF11291.3 OAJ29671.1 - 0.12 12.3 1.1 0.34 10.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) EURL PF06937.6 OAJ29671.1 - 0.12 11.7 3.3 0.15 11.4 2.3 1.1 1 0 0 1 1 1 0 EURL protein DUF4559 PF15112.1 OAJ29671.1 - 0.19 10.8 7.8 0.24 10.5 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Tweety PF04906.8 OAJ29671.1 - 0.42 8.9 2.2 0.39 9.0 0.8 1.4 1 1 0 1 1 1 0 Tweety FlxA PF14282.1 OAJ29671.1 - 0.61 10.0 12.0 1.1 9.2 4.5 2.3 1 1 1 2 2 2 0 FlxA-like protein Prefoldin_2 PF01920.15 OAJ29671.1 - 0.82 9.4 16.9 5.1 6.9 0.6 3.6 2 1 1 3 3 3 0 Prefoldin subunit DUF2730 PF10805.3 OAJ29671.1 - 0.99 9.1 6.4 4.6 7.0 0.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) DUF848 PF05852.6 OAJ29671.1 - 1.7 8.5 11.4 0.95 9.3 5.7 2.1 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) NPV_P10 PF05531.7 OAJ29671.1 - 2.2 8.5 6.7 1.7 8.9 0.7 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 OAJ29671.1 - 2.5 5.8 9.7 5.5 4.7 3.0 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 OAJ29671.1 - 3.5 5.9 9.3 1.4 7.2 3.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) SseC PF04888.7 OAJ29671.1 - 4.7 6.4 9.6 0.6 9.3 1.9 2.4 2 1 0 2 2 2 0 Secretion system effector C (SseC) like family THP2 PF09432.5 OAJ29671.1 - 4.9 7.0 7.3 3.3 7.5 1.9 2.5 1 1 2 3 3 3 0 Tho complex subunit THP2 Mnd1 PF03962.10 OAJ29671.1 - 5.3 6.6 13.9 18 4.9 0.8 2.2 1 1 1 2 2 2 0 Mnd1 family EMP24_GP25L PF01105.19 OAJ29671.1 - 5.5 6.6 6.8 8.1 6.1 0.0 2.8 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Totivirus_coat PF05518.6 OAJ29672.1 - 5.6 4.6 16.0 7.8 4.1 11.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein ADH_N PF08240.7 OAJ29673.1 - 5.9e-27 93.5 1.9 6.5e-27 93.4 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ29673.1 - 9.7e-24 83.3 0.4 9.7e-24 83.3 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ29673.1 - 0.0044 17.9 1.3 0.0082 17.0 0.7 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase mono-CXXC PF15626.1 OAJ29673.1 - 0.047 13.6 0.7 0.14 12.0 0.5 1.8 1 0 0 1 1 1 0 single CXXC unit ACP_syn_III_C PF08541.5 OAJ29673.1 - 0.066 13.2 0.5 0.46 10.5 0.1 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Glyco_hydro_92 PF07971.7 OAJ29674.1 - 1.2e-82 278.2 0.2 1.6e-82 277.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Rrn6 PF10214.4 OAJ29676.1 - 0.0001 20.5 8.1 0.078 11.0 0.2 3.5 2 2 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor Pkinase PF00069.20 OAJ29678.1 - 1.4e-46 158.7 0.0 9.3e-44 149.5 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ29678.1 - 2.1e-22 79.4 0.0 6.9e-22 77.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 OAJ29678.1 - 0.0026 16.8 0.1 0.0041 16.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ29678.1 - 0.054 12.4 0.0 0.19 10.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Ecl1 PF12855.2 OAJ29679.1 - 4.3e-06 25.8 0.7 8.5e-06 24.9 0.5 1.5 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 OAJ29679.1 - 0.00038 20.2 1.5 0.001 18.8 1.0 1.7 1 0 0 1 1 1 1 MYND finger Dicty_REP PF05086.7 OAJ29679.1 - 1.8 6.1 5.3 3.3 5.3 3.7 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RNA_pol_3_Rpc31 PF11705.3 OAJ29680.1 - 0.016 15.1 5.2 0.028 14.3 3.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.7 OAJ29680.1 - 0.73 9.0 4.3 1 8.5 3.0 1.2 1 0 0 1 1 1 0 NOA36 protein TB2_DP1_HVA22 PF03134.14 OAJ29681.1 - 1.4e-31 108.0 4.9 1.8e-31 107.7 3.4 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Polysacc_synt_C PF14667.1 OAJ29681.1 - 0.045 13.5 3.7 0.064 13.0 2.6 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain MFS_1 PF07690.11 OAJ29682.1 - 2.9e-46 157.7 38.2 2.2e-45 154.8 11.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ29682.1 - 3.4e-08 32.4 10.7 3.4e-08 32.4 7.4 3.5 2 2 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 OAJ29682.1 - 2.2e-06 26.0 1.4 0.00022 19.4 1.0 2.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.8 OAJ29682.1 - 1.2e-05 23.7 4.4 2.3e-05 22.7 3.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 OAJ29682.1 - 0.0014 16.8 4.3 0.0029 15.7 3.0 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector DUF4231 PF14015.1 OAJ29682.1 - 0.018 15.0 7.3 3.1 7.8 0.5 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF21 PF01595.15 OAJ29682.1 - 0.025 13.8 0.9 0.025 13.8 0.6 3.0 2 0 0 2 2 2 0 Domain of unknown function DUF21 ESSS PF10183.4 OAJ29682.1 - 0.063 13.6 0.2 0.26 11.6 0.1 2.0 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) SQS_PSY PF00494.14 OAJ29683.1 - 1.4e-46 159.0 1.4 1.7e-46 158.6 0.9 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase BCIP PF13862.1 OAJ29684.1 - 2.9e-32 111.7 0.0 4.7e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Spt5_N PF11942.3 OAJ29684.1 - 0.3 11.7 6.5 2.8 8.6 2.9 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal NIF PF03031.13 OAJ29685.1 - 1.2e-49 168.0 0.1 1.9e-49 167.4 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Nucleoplasmin PF03066.10 OAJ29685.1 - 0.82 9.1 9.6 1.5 8.2 6.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 OAJ29685.1 - 4 7.0 12.8 10 5.6 8.9 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 OAJ29685.1 - 8.3 5.5 7.8 14 4.8 5.4 1.2 1 0 0 1 1 1 0 NOA36 protein ORC2 PF04084.9 OAJ29686.1 - 2.8e-37 128.2 0.0 2e-31 109.0 0.0 2.1 2 0 0 2 2 2 2 Origin recognition complex subunit 2 OATP PF03137.15 OAJ29686.1 - 0.062 11.3 0.0 0.19 9.7 0.0 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TFIID_30kDa PF03540.8 OAJ29686.1 - 0.08 12.7 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit PBP1_TM PF14812.1 OAJ29686.1 - 8.9 6.6 21.8 1.7 8.9 0.0 5.2 6 0 0 6 6 6 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RhoGAP PF00620.22 OAJ29687.1 - 1.4e-06 27.9 0.1 7.2e-05 22.4 0.0 3.3 3 1 0 3 3 3 1 RhoGAP domain FCH PF00611.18 OAJ29687.1 - 0.00021 21.3 0.1 0.0069 16.5 0.0 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain TPP_enzyme_N PF02776.13 OAJ29688.1 - 1.7e-54 183.8 0.0 1.7e-54 183.8 0.0 3.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 OAJ29688.1 - 1e-47 161.5 0.1 3.2e-46 156.6 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAJ29688.1 - 5.5e-38 129.8 0.7 1.5e-37 128.4 0.2 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain RRM_1 PF00076.17 OAJ29689.1 - 3.7e-34 116.1 0.0 8.3e-17 60.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ29689.1 - 2.2e-26 91.5 0.0 6.7e-12 45.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ29689.1 - 9.5e-11 41.3 0.0 0.00029 20.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDK2AP PF09806.4 OAJ29689.1 - 0.00029 21.1 3.0 0.00029 21.1 2.1 3.6 2 1 0 2 2 2 1 Cyclin-dependent kinase 2-associated protein RRM_3 PF08777.6 OAJ29689.1 - 0.14 12.0 0.3 22 4.9 0.0 3.3 3 0 0 3 3 3 0 RNA binding motif Med11 PF10280.4 OAJ29690.1 - 9.8e-06 25.6 0.0 1.6e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Mediator complex protein DUF938 PF06080.7 OAJ29691.1 - 5.5e-29 101.1 0.0 7.6e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_18 PF12847.2 OAJ29691.1 - 0.0015 19.0 0.1 0.0037 17.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ29691.1 - 0.004 16.8 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ29691.1 - 0.022 15.2 0.1 0.09 13.2 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ29691.1 - 0.14 12.5 0.1 0.95 9.8 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Scs3p PF10261.4 OAJ29692.1 - 3.7e-48 163.6 0.0 6.1e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM YsaB PF13983.1 OAJ29692.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 YsaB-like lipoprotein DUF221 PF02714.10 OAJ29693.1 - 2e-39 135.3 16.0 2.9e-39 134.8 11.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAJ29693.1 - 1.9e-15 56.7 2.6 1.9e-15 56.7 1.8 3.8 4 1 1 5 5 5 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 OAJ29693.1 - 0.00087 19.7 0.8 0.06 13.8 0.0 3.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 OAJ29693.1 - 0.0048 16.8 0.0 3.3 7.7 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Katanin_con80 PF13925.1 OAJ29693.1 - 0.12 12.1 0.6 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 con80 domain of Katanin DHO_dh PF01180.16 OAJ29694.1 - 7.1e-91 304.2 0.0 1e-90 303.7 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 OAJ29694.1 - 0.00037 19.4 0.0 0.0067 15.3 0.0 2.9 3 1 0 3 3 3 1 FMN-dependent dehydrogenase NMO PF03060.10 OAJ29694.1 - 0.0019 17.4 0.0 0.005 16.0 0.0 1.7 1 0 0 1 1 1 1 Nitronate monooxygenase FA_hydroxylase PF04116.8 OAJ29695.1 - 4.9e-14 52.7 26.4 1.4e-13 51.2 15.6 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_60s PF00428.14 OAJ29695.1 - 0.083 13.2 6.8 0.15 12.4 4.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Gly-zipper_OmpA PF13436.1 OAJ29695.1 - 3.3 7.4 9.2 0.49 10.0 3.6 1.5 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Ribosomal_L2_C PF03947.13 OAJ29696.1 - 2.1e-41 140.7 1.1 2.9e-41 140.2 0.8 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Tom22 PF04281.8 OAJ29698.1 - 0.02 14.4 0.1 11 5.4 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 MFS_1 PF07690.11 OAJ29699.1 - 6.3e-40 136.9 50.1 8.1e-35 120.1 32.9 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.23 OAJ29700.1 - 2.1e-50 171.3 0.0 2.9e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ29700.1 - 0.0094 16.8 0.0 0.02 15.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.19 OAJ29701.1 - 2.9e-35 121.7 19.7 6.3e-35 120.6 13.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ29701.1 - 1.7e-24 86.1 33.3 1.7e-24 86.1 23.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Cutinase PF01083.17 OAJ29702.1 - 1e-28 100.2 0.0 1.2e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ29702.1 - 0.00035 20.2 0.1 0.00035 20.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 OAJ29702.1 - 0.0024 18.1 0.0 0.003 17.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.6 OAJ29702.1 - 0.0026 17.2 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_8 PF06259.7 OAJ29702.1 - 0.02 14.4 0.1 0.051 13.0 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase Abhydrolase_9 PF10081.4 OAJ29702.1 - 0.04 12.6 0.0 0.062 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Abhydrolase_2 PF02230.11 OAJ29702.1 - 0.061 12.7 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.6 OAJ29702.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Sugar_tr PF00083.19 OAJ29703.1 - 1.2e-34 119.6 21.7 2.7e-34 118.5 15.1 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ29703.1 - 2.2e-28 99.0 35.6 2.2e-28 99.0 24.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 OAJ29703.1 - 0.011 15.5 1.6 0.56 10.0 0.1 3.3 2 1 1 3 3 3 0 MFS_1 like family Ank_2 PF12796.2 OAJ29706.1 - 5.3e-12 45.9 0.1 2.9e-11 43.5 0.1 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ29706.1 - 5.1e-10 38.6 1.2 0.008 15.9 0.1 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 OAJ29706.1 - 6.1e-08 32.9 0.0 0.00024 21.4 0.0 3.8 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ29706.1 - 7.4e-07 28.8 0.0 0.23 11.7 0.0 4.8 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 OAJ29706.1 - 1.8e-06 28.0 0.1 0.021 15.0 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Glyco_hydro_18 PF00704.23 OAJ29707.1 - 2.5e-82 277.0 3.8 3.1e-82 276.8 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 OAJ29707.1 - 3e-08 33.4 23.3 6.2e-08 32.4 16.1 1.6 1 0 0 1 1 1 1 Chitin recognition protein HRM PF02793.17 OAJ29707.1 - 0.0029 17.5 0.2 0.0029 17.5 0.2 2.0 2 0 0 2 2 2 1 Hormone receptor domain LysM PF01476.15 OAJ29708.1 - 5.8e-53 176.5 11.2 1.9e-15 56.4 0.0 6.6 6 0 0 6 6 6 6 LysM domain EF-hand_6 PF13405.1 OAJ29708.1 - 1.3e-08 34.0 0.1 0.0014 18.3 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 OAJ29708.1 - 4.3e-08 31.9 0.1 0.0029 16.7 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 OAJ29708.1 - 2e-06 26.8 1.8 0.0069 15.6 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 OAJ29708.1 - 2.7e-05 24.2 0.0 0.38 10.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 OAJ29708.1 - 0.02 14.5 0.2 0.31 10.6 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair XPA_C PF05181.7 OAJ29710.1 - 2.1e-27 94.4 1.2 5e-27 93.2 0.8 1.7 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 OAJ29710.1 - 0.61 9.8 6.8 0.33 10.6 0.8 2.3 2 0 0 2 2 2 0 XPA protein N-terminal Stc1 PF12898.2 OAJ29710.1 - 3.7 7.6 8.1 7 6.7 0.4 2.7 2 1 0 2 2 2 0 Stc1 domain SPT6_acidic PF14632.1 OAJ29710.1 - 5.7 7.1 8.6 0.28 11.3 0.5 2.5 2 0 0 2 2 2 0 Acidic N-terminal SPT6 E1-E2_ATPase PF00122.15 OAJ29711.1 - 4.8e-57 192.6 4.9 9.5e-57 191.6 3.4 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAJ29711.1 - 9.5e-35 119.7 1.5 9.5e-35 119.7 1.1 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ29711.1 - 1.2e-26 94.5 1.3 2.7e-21 76.9 0.1 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAJ29711.1 - 1.7e-16 59.4 2.3 2e-16 59.1 0.0 2.3 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 OAJ29711.1 - 5.1e-12 45.5 0.0 1.6e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 OAJ29711.1 - 3.1e-11 43.7 0.0 1.1e-10 41.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ29711.1 - 0.058 12.9 0.1 1.9 8.0 0.1 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 OAJ29712.1 - 4.3e-36 124.3 0.0 5.9e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ29712.1 - 2.4e-23 82.5 0.0 3.3e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AhpC-TSA PF00578.16 OAJ29713.1 - 3.1e-34 117.3 0.0 4.4e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 OAJ29713.1 - 1.3e-13 50.7 0.0 1.6e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 OAJ29713.1 - 7.7e-11 41.4 0.1 1.5e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin GATase_2 PF00310.16 OAJ29713.1 - 0.11 11.2 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferases class-II ACOX PF01756.14 OAJ29714.1 - 4.4e-45 153.3 0.0 7.3e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 OAJ29714.1 - 5.4e-15 54.6 0.7 1.4e-14 53.2 0.2 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 OAJ29714.1 - 3.7e-11 43.4 0.0 1.1e-10 41.9 0.0 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 OAJ29714.1 - 8.5e-10 38.9 0.9 3.5e-09 36.9 0.6 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Endonuclease_5 PF04493.9 OAJ29715.1 - 2.3e-37 128.3 0.0 3.9e-37 127.6 0.0 1.5 1 1 0 1 1 1 1 Endonuclease V CDC27 PF09507.5 OAJ29716.1 - 0.0022 17.2 6.9 0.0051 16.1 4.8 1.6 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 zf-C2H2 PF00096.21 OAJ29716.1 - 0.04 14.2 5.3 0.21 12.0 3.7 2.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Nop14 PF04147.7 OAJ29716.1 - 0.9 7.3 21.3 1.3 6.8 14.7 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 OAJ29716.1 - 6.5 5.6 19.9 11 5.0 13.8 1.3 1 0 0 1 1 1 0 BUD22 Methyltransf_23 PF13489.1 OAJ29717.1 - 3.8e-06 26.7 0.0 7.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ29717.1 - 0.046 14.1 0.0 0.33 11.4 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain DUF2457 PF10446.4 OAJ29717.1 - 0.062 12.0 18.3 0.03 13.0 7.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 OAJ29717.1 - 1.2 8.3 7.8 2.4 7.3 5.4 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 OAJ29717.1 - 3.8 5.4 9.7 8.8 4.2 6.7 1.6 1 0 0 1 1 1 0 CDC45-like protein DDE_3 PF13358.1 OAJ29719.1 - 1.4e-32 112.4 0.0 2.1e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 OAJ29719.1 - 6e-08 32.1 0.0 5.2e-06 25.8 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 OAJ29719.1 - 3.6e-05 24.4 0.2 3.6e-05 24.4 0.1 2.5 3 0 0 3 3 3 1 Homeodomain-like domain rve PF00665.21 OAJ29719.1 - 7e-05 22.9 0.0 0.00013 22.0 0.0 1.6 1 1 0 1 1 1 1 Integrase core domain HTH_29 PF13551.1 OAJ29719.1 - 0.00031 20.8 0.1 0.0011 19.1 0.0 2.0 2 1 0 2 2 2 1 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 OAJ29719.1 - 0.17 10.6 0.0 0.29 9.8 0.0 1.3 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain rve PF00665.21 OAJ29720.1 - 3.2e-14 53.0 0.0 9e-14 51.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ29720.1 - 7.3e-12 45.0 0.1 1.6e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 OAJ29720.1 - 1.4e-06 28.0 0.0 4.8e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 OAJ29720.1 - 5.9e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.19 OAJ29720.1 - 9.7e-05 21.9 1.2 0.00025 20.6 0.3 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 OAJ29720.1 - 0.00023 21.5 0.0 0.00052 20.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 OAJ29720.1 - 0.00091 19.0 2.4 0.0017 18.1 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 OAJ29720.1 - 0.007 16.0 0.5 0.025 14.2 0.3 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ29720.1 - 0.016 14.9 0.1 0.045 13.4 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle PseudoU_synth_1 PF01416.15 OAJ29721.1 - 1e-16 61.2 0.0 1.1e-07 32.1 0.0 3.0 2 1 0 2 2 2 2 tRNA pseudouridine synthase GST_N_3 PF13417.1 OAJ29722.1 - 5.6e-07 29.6 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ29722.1 - 0.015 15.2 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GCR1_C PF12550.3 OAJ29723.1 - 2.6e-09 36.8 0.1 7.6e-09 35.3 0.1 1.8 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DcpS_C PF11969.3 OAJ29723.1 - 0.056 13.6 0.2 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding F-box PF00646.28 OAJ29724.1 - 0.079 12.6 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 OAJ29725.1 - 0.72 9.6 3.9 3 7.6 0.6 2.7 2 0 0 2 2 2 0 F-box-like DUF3584 PF12128.3 OAJ29726.1 - 7.4e-05 20.3 0.6 8.4e-05 20.1 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CENP-Q PF13094.1 OAJ29726.1 - 0.0017 18.4 6.7 0.0024 17.9 4.6 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF883 PF05957.8 OAJ29726.1 - 0.0023 18.2 8.4 0.0023 18.2 5.8 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) FPN1 PF06963.7 OAJ29726.1 - 0.0093 14.3 0.1 0.011 14.1 0.1 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) TMCO5 PF14992.1 OAJ29726.1 - 0.012 14.7 1.5 0.015 14.4 1.0 1.1 1 0 0 1 1 1 0 TMCO5 family Prominin PF05478.6 OAJ29726.1 - 0.013 13.1 0.1 0.015 12.8 0.1 1.0 1 0 0 1 1 1 0 Prominin Borrelia_P83 PF05262.6 OAJ29726.1 - 0.017 13.4 3.1 0.019 13.2 2.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ATP-synt_B PF00430.13 OAJ29726.1 - 0.05 13.4 10.2 0.12 12.2 7.1 1.6 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) RRF PF01765.14 OAJ29726.1 - 0.072 12.5 3.9 0.099 12.1 2.7 1.2 1 0 0 1 1 1 0 Ribosome recycling factor RR_TM4-6 PF06459.7 OAJ29726.1 - 0.26 11.1 5.3 0.32 10.8 3.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2317 PF10079.4 OAJ29726.1 - 0.54 8.8 4.9 0.67 8.5 3.4 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Peptidase_S49_N PF08496.5 OAJ29726.1 - 0.73 9.6 5.9 1.1 9.0 4.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal vATP-synt_E PF01991.13 OAJ29726.1 - 3 7.0 11.5 5 6.3 8.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Fzo_mitofusin PF04799.8 OAJ29726.1 - 8.7 5.6 9.0 2.6 7.4 2.6 2.1 1 1 1 2 2 2 0 fzo-like conserved region Zw10 PF06248.8 OAJ29727.1 - 0.00097 17.4 0.7 0.079 11.0 0.0 2.8 3 0 0 3 3 3 2 Centromere/kinetochore Zw10 PUF PF00806.14 OAJ29728.1 - 2.4e-11 42.4 0.0 0.016 14.6 0.0 5.9 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat Adaptin_binding PF10199.4 OAJ29728.1 - 0.19 11.9 26.3 1.3 9.2 1.7 4.1 4 0 0 4 4 4 0 Alpha and gamma adaptin binding protein p34 Tim54 PF11711.3 OAJ29728.1 - 0.21 10.1 22.7 0.057 12.0 1.1 3.4 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 Bot1p PF12298.3 OAJ29729.1 - 5.4e-23 81.8 1.3 6.3e-23 81.5 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.2 OAJ29729.1 - 0.038 13.9 0.0 0.038 13.9 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal protein subunit L20 TPR_11 PF13414.1 OAJ29730.1 - 2.3e-36 123.2 20.8 2.9e-14 52.4 2.5 5.5 4 1 1 5 5 5 5 TPR repeat TPR_2 PF07719.12 OAJ29730.1 - 2e-25 86.5 18.1 0.00034 20.3 0.1 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ29730.1 - 3.4e-23 80.2 12.8 0.0038 16.7 0.1 7.5 7 0 0 7 7 7 7 Tetratricopeptide repeat DnaJ PF00226.26 OAJ29730.1 - 9e-23 79.7 1.5 3.4e-22 77.9 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_16 PF13432.1 OAJ29730.1 - 1.5e-22 79.6 17.9 5.3e-05 23.7 0.1 6.2 3 2 2 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ29730.1 - 6.4e-19 68.0 19.9 1.6e-06 28.3 0.6 6.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ29730.1 - 1.3e-16 60.2 18.0 1e-05 25.3 0.2 5.7 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ29730.1 - 1.9e-16 59.0 17.4 0.0042 17.6 0.0 6.5 5 1 1 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 OAJ29730.1 - 6.9e-12 45.3 10.7 0.00023 21.2 0.2 3.7 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 OAJ29730.1 - 1e-08 34.3 13.9 0.3 10.9 0.1 7.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ29730.1 - 5.4e-08 32.5 11.9 0.012 15.4 0.4 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ29730.1 - 3.6e-06 26.3 10.5 0.28 11.0 0.1 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ29730.1 - 6.7e-06 25.8 8.6 12 6.3 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ29730.1 - 1.4e-05 25.1 20.5 0.24 11.9 0.0 7.1 7 0 0 7 7 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 OAJ29730.1 - 0.00015 21.6 10.7 0.013 15.4 0.1 4.9 4 1 1 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 OAJ29730.1 - 0.022 15.1 4.7 0.4 11.2 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1840 PF08895.6 OAJ29730.1 - 0.31 11.0 6.3 0.39 10.7 0.8 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) MIT PF04212.13 OAJ29730.1 - 1.2 9.1 17.7 6.2 6.7 0.0 5.0 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 OAJ29730.1 - 1.2 9.1 14.6 2.5 8.1 0.4 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat ICL PF00463.16 OAJ29731.1 - 1.3e-159 531.8 0.0 1.4e-159 531.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 OAJ29731.1 - 4e-10 39.3 0.0 7.2e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 OAJ29731.1 - 0.0033 16.8 0.1 0.0068 15.8 0.0 1.5 1 0 0 1 1 1 1 Arginine repressor, C-terminal domain Rad9 PF04139.8 OAJ29732.1 - 7.1e-39 133.4 0.0 4e-38 130.9 0.0 2.0 1 1 0 1 1 1 1 Rad9 DUF953 PF06110.6 OAJ29732.1 - 4.2e-17 61.6 0.0 7e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.15 OAJ29732.1 - 0.0048 16.5 0.0 0.04 13.6 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_9 PF14595.1 OAJ29732.1 - 0.16 11.5 0.2 0.33 10.5 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin MAPEG PF01124.13 OAJ29733.1 - 4.4e-10 39.2 6.2 9.8e-10 38.1 4.3 1.8 1 1 0 1 1 1 1 MAPEG family DUF1227 PF06777.6 OAJ29734.1 - 8.7e-57 190.9 0.1 1.7e-56 190.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 OAJ29734.1 - 9.2e-46 155.4 0.1 1.2e-40 138.7 0.0 2.4 2 0 0 2 2 2 2 DEAD_2 Helicase_C_2 PF13307.1 OAJ29734.1 - 1.3e-45 155.3 0.0 2.9e-45 154.2 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 OAJ29734.1 - 0.0033 16.2 0.2 0.051 12.3 0.1 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 OAJ29734.1 - 0.0075 16.1 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ29734.1 - 0.014 14.9 0.0 3 7.3 0.0 2.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ29734.1 - 0.039 14.1 0.1 4.1 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 OAJ29734.1 - 0.069 12.9 0.0 0.62 9.8 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain YtxC PF08812.6 OAJ29734.1 - 0.079 12.4 0.4 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 YtxC-like family AAA_11 PF13086.1 OAJ29734.1 - 0.12 11.9 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Phyto-Amp PF15438.1 OAJ29735.1 - 0.002 17.7 1.8 0.24 11.0 0.2 2.1 1 1 1 2 2 2 2 Antigenic membrane protein of phytoplasma PTR PF12789.2 OAJ29735.1 - 0.04 13.7 0.1 0.064 13.1 0.1 1.3 1 0 0 1 1 1 0 Phage tail repeat like ABC_tran PF00005.22 OAJ29736.1 - 4.7e-45 153.2 0.1 2.6e-22 79.5 0.0 4.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 OAJ29736.1 - 4.2e-19 69.5 1.6 3.8e-07 30.3 0.0 4.3 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 OAJ29736.1 - 8.9e-15 54.5 1.7 0.011 14.9 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 OAJ29736.1 - 6.3e-10 38.4 0.2 0.00081 18.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 OAJ29736.1 - 1.9e-06 28.7 0.1 0.099 13.4 0.1 3.2 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 OAJ29736.1 - 2e-06 27.6 0.0 0.0047 16.8 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 OAJ29736.1 - 3.6e-06 26.6 0.1 0.011 15.1 0.0 3.1 3 0 0 3 3 2 2 AAA-like domain AAA_22 PF13401.1 OAJ29736.1 - 6.4e-06 26.3 0.0 0.32 11.1 0.0 4.2 5 0 0 5 5 4 2 AAA domain AAA_15 PF13175.1 OAJ29736.1 - 1.9e-05 23.8 0.4 0.42 9.5 0.0 4.3 4 1 0 5 5 4 1 AAA ATPase domain HEAT_2 PF13646.1 OAJ29736.1 - 2.3e-05 24.5 0.6 0.0071 16.6 0.0 4.2 4 1 1 5 5 4 1 HEAT repeats DUF258 PF03193.11 OAJ29736.1 - 3.1e-05 23.2 0.0 0.032 13.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 OAJ29736.1 - 3.2e-05 24.3 0.0 0.038 14.4 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 OAJ29736.1 - 3.3e-05 24.2 9.1 0.058 13.7 0.0 3.7 3 1 0 3 3 2 2 AAA domain NACHT PF05729.7 OAJ29736.1 - 3.5e-05 23.5 0.0 0.28 10.8 0.0 3.2 3 0 0 3 3 3 2 NACHT domain MMR_HSR1 PF01926.18 OAJ29736.1 - 6.5e-05 22.8 0.0 0.47 10.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 OAJ29736.1 - 8.5e-05 22.8 1.8 0.39 11.0 0.0 4.1 4 0 0 4 4 3 1 AAA domain HEAT_EZ PF13513.1 OAJ29736.1 - 0.00011 22.5 3.3 4.8 7.7 0.0 5.4 5 1 1 6 6 5 0 HEAT-like repeat Chromo PF00385.19 OAJ29736.1 - 0.00012 21.6 0.5 0.00028 20.4 0.0 1.9 2 0 0 2 2 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_33 PF13671.1 OAJ29736.1 - 0.00016 21.5 0.0 0.77 9.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_13 PF13166.1 OAJ29736.1 - 0.00029 19.4 0.1 1.1 7.5 0.0 3.4 3 1 0 3 3 3 1 AAA domain DUF87 PF01935.12 OAJ29736.1 - 0.00036 20.4 3.2 0.032 14.0 0.1 3.3 4 0 0 4 4 3 1 Domain of unknown function DUF87 AAA_25 PF13481.1 OAJ29736.1 - 0.0004 19.8 0.1 0.44 9.9 0.0 3.6 4 0 0 4 4 3 1 AAA domain MobB PF03205.9 OAJ29736.1 - 0.00043 19.9 0.3 0.61 9.7 0.0 3.2 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 OAJ29736.1 - 0.00063 19.8 0.0 0.88 9.7 0.0 2.8 2 0 0 2 2 2 1 RNA helicase FtsK_SpoIIIE PF01580.13 OAJ29736.1 - 0.00093 18.7 0.1 0.95 8.8 0.0 2.9 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 OAJ29736.1 - 0.0011 19.0 5.1 0.12 12.3 0.5 4.2 3 1 0 3 3 3 1 AAA ATPase domain CLASP_N PF12348.3 OAJ29736.1 - 0.0011 18.3 0.1 0.56 9.5 0.0 2.5 1 1 0 2 2 2 1 CLASP N terminal G-alpha PF00503.15 OAJ29736.1 - 0.0013 17.5 0.1 0.98 8.0 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit ArgK PF03308.11 OAJ29736.1 - 0.0015 17.3 0.3 0.48 9.1 0.0 2.9 2 0 0 2 2 2 1 ArgK protein HEAT PF02985.17 OAJ29736.1 - 0.0019 18.1 1.1 1.8 8.8 0.0 4.7 5 0 0 5 5 4 1 HEAT repeat Arch_ATPase PF01637.13 OAJ29736.1 - 0.0021 17.8 0.6 1.9 8.1 0.1 3.7 3 1 0 3 3 3 1 Archaeal ATPase AAA_28 PF13521.1 OAJ29736.1 - 0.0024 17.8 0.0 0.86 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 OAJ29736.1 - 0.0032 17.6 0.0 6.5 6.9 0.0 4.4 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 OAJ29736.1 - 0.0045 16.5 0.1 6.6 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 OAJ29736.1 - 0.0055 16.6 0.0 4.3 7.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 OAJ29736.1 - 0.0082 15.0 1.4 2.1 7.1 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain Zeta_toxin PF06414.7 OAJ29736.1 - 0.014 14.5 1.9 21 4.1 0.0 3.4 3 0 0 3 3 3 0 Zeta toxin cobW PF02492.14 OAJ29736.1 - 0.033 13.6 1.9 11 5.3 0.1 3.8 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 OAJ29736.1 - 0.058 12.9 0.5 4.1 6.8 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 OAJ29736.1 - 0.077 12.7 2.3 9.1 6.0 0.0 4.1 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) Solute_trans_a PF03619.11 OAJ29737.1 - 2e-86 289.7 8.6 2.7e-86 289.3 6.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha WD40 PF00400.27 OAJ29738.1 - 9.4e-25 85.5 10.8 1.1e-06 28.2 0.2 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat LRS4 PF10422.4 OAJ29739.1 - 0.23 10.7 9.4 0.64 9.3 0.4 2.6 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 AAA PF00004.24 OAJ29740.1 - 7.5e-19 68.2 0.0 5e-09 36.4 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 OAJ29740.1 - 1.4e-12 47.6 1.4 1.7e-11 44.0 1.0 2.3 1 1 0 1 1 1 1 BCS1 N terminal AAA_19 PF13245.1 OAJ29740.1 - 0.0048 16.6 0.0 0.017 14.8 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 OAJ29740.1 - 0.0058 16.7 0.0 0.049 13.7 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_11 PF13086.1 OAJ29740.1 - 0.0071 15.9 0.0 0.03 13.9 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ29740.1 - 0.0093 16.7 0.0 0.03 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ29740.1 - 0.02 14.8 0.8 0.11 12.4 0.2 2.7 1 1 1 2 2 2 0 AAA ATPase domain RuvB_N PF05496.7 OAJ29740.1 - 0.042 12.8 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus TMEM240 PF15207.1 OAJ29740.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 TMEM240 family Med22 PF06179.7 OAJ29741.1 - 2.5e-13 49.9 0.2 3.7e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Brix PF04427.13 OAJ29742.1 - 4.2e-21 75.4 0.0 1.1e-20 74.1 0.0 1.6 1 1 0 1 1 1 1 Brix domain Nop14 PF04147.7 OAJ29742.1 - 0.66 7.8 36.7 0.94 7.3 25.4 1.2 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 OAJ29742.1 - 0.8 8.8 20.4 1.5 8.0 14.1 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 OAJ29742.1 - 2.6 6.4 29.0 4.3 5.7 20.1 1.4 1 0 0 1 1 1 0 Daxx Family Paf1 PF03985.8 OAJ29742.1 - 2.7 6.6 17.6 4.3 5.9 12.2 1.3 1 0 0 1 1 1 0 Paf1 PIG-X PF08320.7 OAJ29744.1 - 6.5e-12 45.1 0.0 0.00059 19.1 0.0 3.4 3 1 0 3 3 3 3 PIG-X / PBN1 Hist_deacetyl PF00850.14 OAJ29745.1 - 1.8e-51 175.3 0.0 2.6e-51 174.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Rad17 PF03215.10 OAJ29746.1 - 2.3e-37 128.8 0.0 3.7e-14 52.3 0.0 4.4 4 1 0 4 4 4 3 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 OAJ29746.1 - 1.5e-06 28.3 0.0 6.3e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ29746.1 - 0.0001 22.4 0.0 0.00037 20.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 OAJ29746.1 - 0.0048 16.1 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 OAJ29746.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 OAJ29746.1 - 0.016 14.3 0.0 0.038 13.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 OAJ29746.1 - 0.021 15.6 0.0 0.098 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 OAJ29746.1 - 0.028 13.9 0.0 0.085 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.16 OAJ29746.1 - 0.046 13.1 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA_28 PF13521.1 OAJ29746.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 OAJ29746.1 - 0.092 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zn_clus PF00172.13 OAJ29747.1 - 1.8e-08 34.1 7.6 2.8e-08 33.5 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phosphodiest PF01663.17 OAJ29748.1 - 5.6e-52 177.2 0.0 1.9e-49 168.9 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 OAJ29748.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily SPT6_acidic PF14632.1 OAJ29748.1 - 0.18 12.0 11.4 0.07 13.3 3.7 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Ribosomal_L1 PF00687.16 OAJ29749.1 - 2.7e-46 157.6 0.0 8.3e-46 156.0 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family PGC7_Stella PF15549.1 OAJ29749.1 - 0.037 14.0 0.6 0.037 14.0 0.4 2.4 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain TFIIA PF03153.8 OAJ29749.1 - 0.35 10.7 27.6 0.099 12.5 3.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nucleoplasmin PF03066.10 OAJ29749.1 - 0.38 10.2 10.1 0.66 9.4 7.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin CAP_GLY PF01302.20 OAJ29750.1 - 1.6e-14 53.3 0.4 2.8e-14 52.5 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain zf-CCHC_4 PF14392.1 OAJ29750.1 - 0.25 11.0 6.4 1.5 8.5 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF3087 PF11286.3 OAJ29750.1 - 0.94 8.6 2.4 2 7.6 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Snf7 PF03357.16 OAJ29751.1 - 9.3e-19 67.4 7.3 1.3e-18 66.9 5.1 1.2 1 0 0 1 1 1 1 Snf7 ACR_tran PF00873.14 OAJ29751.1 - 0.067 10.5 0.2 0.098 10.0 0.1 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family MCPVI PF02993.9 OAJ29751.1 - 2.4 8.2 8.3 0.3 11.1 2.0 2.1 2 0 0 2 2 2 0 Minor capsid protein VI DUF1191 PF06697.7 OAJ29752.1 - 0.002 16.9 0.0 0.0033 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 OAJ29752.1 - 0.0091 16.3 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 OAJ29752.1 - 0.15 11.7 0.8 0.31 10.7 0.6 1.4 1 0 0 1 1 1 0 Syndecan domain YajC PF02699.10 OAJ29752.1 - 0.23 11.1 0.0 0.36 10.5 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit DUF572 PF04502.8 OAJ29753.1 - 1.6e-57 195.1 2.2 2.1e-57 194.7 1.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF3052 PF11253.3 OAJ29753.1 - 0.0045 16.5 0.2 0.0075 15.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3052) DUF1315 PF07023.7 OAJ29753.1 - 0.027 14.3 0.1 0.069 13.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1315) HALZ PF02183.13 OAJ29754.1 - 0.33 10.6 1.9 1.3 8.8 1.2 1.6 1 1 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 OAJ29754.1 - 0.82 9.5 6.9 0.4 10.5 2.0 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Pectate_lyase_3 PF12708.2 OAJ29755.1 - 6e-68 229.3 5.3 2.9e-48 164.9 2.7 2.8 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 OAJ29755.1 - 2.1e-05 23.8 1.7 0.051 13.0 0.0 3.4 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 OAJ29755.1 - 0.0031 17.2 2.8 0.0096 15.6 1.6 2.1 1 1 0 1 1 1 1 Right handed beta helix region Sec15 PF04091.7 OAJ29756.1 - 4.4e-19 68.9 0.2 1.4e-17 64.0 0.0 2.7 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.9 OAJ29756.1 - 1.6e-05 24.5 2.2 2.3e-05 24.0 0.1 2.4 2 1 1 3 3 3 1 Sec8 exocyst complex component specific domain COG5 PF10392.4 OAJ29756.1 - 0.00021 21.2 0.6 0.0068 16.3 0.1 2.9 2 1 1 3 3 3 1 Golgi transport complex subunit 5 Sec5 PF15469.1 OAJ29756.1 - 0.00023 20.9 0.3 0.00067 19.4 0.2 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 OAJ29756.1 - 0.0059 16.4 1.4 0.022 14.6 0.0 2.7 3 0 0 3 3 3 1 Vps51/Vps67 COG2 PF06148.6 OAJ29756.1 - 0.012 15.4 0.6 0.056 13.3 0.4 2.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.4 OAJ29756.1 - 0.03 14.2 0.2 0.24 11.2 0.0 2.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1049 PF06305.6 OAJ29757.1 - 0.054 12.9 0.5 0.1 12.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Daxx PF03344.10 OAJ29757.1 - 2.1 6.7 3.4 3.7 5.9 2.4 1.3 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 OAJ29757.1 - 2.6 5.8 3.7 3.6 5.3 2.6 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 OAJ29757.1 - 4 6.9 10.6 8.5 5.8 7.4 1.5 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 OAJ29757.1 - 6.5 5.9 4.5 11 5.1 3.1 1.3 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.20 OAJ29758.1 - 1.7e-65 220.7 0.0 2e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ29758.1 - 2e-33 115.5 0.0 2.6e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ29758.1 - 6.6e-05 22.0 0.0 8.9e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ29758.1 - 0.04 12.9 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ29758.1 - 0.36 10.5 4.5 0.25 11.0 1.2 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF1970 PF09301.5 OAJ29758.1 - 0.9 9.5 5.4 1.7 8.7 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) Bestrophin PF01062.16 OAJ29760.1 - 3.1e-24 85.4 0.4 3.2e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF2347 PF09804.4 OAJ29761.1 - 5.8e-30 104.5 0.0 1.4e-29 103.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 OAJ29761.1 - 0.0017 16.9 0.0 0.0025 16.3 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 Nucleoplasmin PF03066.10 OAJ29761.1 - 0.043 13.3 9.0 0.5 9.8 1.3 2.3 2 0 0 2 2 2 0 Nucleoplasmin BSP_II PF05432.6 OAJ29761.1 - 0.15 11.3 12.4 1.1 8.5 2.1 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Afi1 PF07792.7 OAJ29761.1 - 0.34 10.8 0.0 0.34 10.8 0.0 2.6 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Myc_N PF01056.13 OAJ29761.1 - 0.89 8.6 11.1 1 8.4 2.1 2.7 2 0 0 2 2 2 0 Myc amino-terminal region Fungal_trans PF04082.13 OAJ29762.1 - 4.7e-28 97.7 0.0 8e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain tRNA-synt_1c PF00749.16 OAJ29763.1 - 7.4e-104 346.7 0.0 1.4e-103 345.9 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 OAJ29763.1 - 2.5e-36 124.9 0.2 4.1e-36 124.2 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 OAJ29763.1 - 2.5e-05 24.6 0.1 7.8e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DSS1_SEM1 PF05160.8 OAJ29763.1 - 0.04 13.6 0.5 0.11 12.3 0.3 1.7 1 0 0 1 1 1 0 DSS1/SEM1 family GST_C_2 PF13410.1 OAJ29763.1 - 0.042 13.7 1.3 0.078 12.8 0.2 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain CS PF04969.11 OAJ29764.1 - 2.2e-07 31.3 0.0 1.6e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 CS domain Isochorismatase PF00857.15 OAJ29765.1 - 1.6e-22 80.2 0.1 5.4e-14 52.4 0.0 2.4 2 0 0 2 2 2 2 Isochorismatase family zf-ZPR1 PF03367.8 OAJ29766.1 - 2.2e-95 316.2 0.3 4e-46 156.1 0.0 3.2 2 1 1 3 3 3 3 ZPR1 zinc-finger domain HypA PF01155.14 OAJ29766.1 - 0.014 15.1 2.9 1.2 8.8 0.2 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 OAJ29766.1 - 0.13 11.5 6.4 5.6 6.3 0.0 3.6 2 2 1 3 3 3 0 zinc-ribbon domain DZR PF12773.2 OAJ29766.1 - 2.4 8.0 11.8 21 5.0 0.2 4.2 3 2 1 4 4 4 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 OAJ29766.1 - 5.3 6.6 12.3 2.1 7.9 0.7 4.0 5 0 0 5 5 5 0 zinc-ribbon domain tRNA-synt_2b PF00587.20 OAJ29767.1 - 5.4e-30 104.2 0.0 1e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ29767.1 - 1.4e-05 24.9 0.0 3.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Kinesin PF00225.18 OAJ29768.1 - 1.8e-109 365.4 0.0 2.9e-109 364.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 OAJ29768.1 - 1.1e-30 106.1 0.0 2.9e-30 104.7 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 OAJ29768.1 - 1.5e-15 57.2 0.0 5e-15 55.5 0.0 1.9 1 0 0 1 1 1 1 PH domain KIF1B PF12423.3 OAJ29768.1 - 5.5e-11 42.3 0.1 1.5e-10 40.9 0.1 1.8 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 OAJ29768.1 - 1.5e-06 28.2 0.0 7.1e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 FHA domain PH_11 PF15413.1 OAJ29768.1 - 0.00033 20.8 0.4 0.0014 18.9 0.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain Prenyltrans_2 PF13249.1 OAJ29769.1 - 1.1e-43 148.2 0.6 1.6e-13 51.0 0.2 4.9 2 2 4 6 6 6 6 Prenyltransferase-like Prenyltrans PF00432.16 OAJ29769.1 - 2e-30 104.0 10.5 2.8e-08 33.1 0.0 7.4 8 0 0 8 8 8 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 OAJ29769.1 - 2.7e-29 101.3 0.6 2.1e-12 47.0 0.1 6.3 3 3 4 7 7 7 5 Prenyltransferase-like Pec_lyase PF09492.5 OAJ29769.1 - 1.8e-08 33.8 0.0 0.042 13.0 0.0 4.5 1 1 3 5 5 5 3 Pectic acid lyase A2M_comp PF07678.9 OAJ29769.1 - 1.1e-05 24.7 0.1 0.014 14.6 0.0 3.9 2 1 2 4 4 4 2 A-macroglobulin complement component Ank_2 PF12796.2 OAJ29770.1 - 8.5e-19 67.6 5.1 4.4e-10 39.7 0.9 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ29770.1 - 3.6e-12 45.4 0.9 6.4e-06 25.7 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 OAJ29770.1 - 3.9e-11 42.0 0.3 0.00034 20.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 OAJ29770.1 - 4.8e-11 42.8 1.3 5.1e-08 33.2 0.2 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ29770.1 - 1.9e-09 37.4 2.2 0.00011 22.3 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) SPT16 PF08644.6 OAJ29770.1 - 0.036 13.8 0.1 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF4407 PF14362.1 OAJ29770.1 - 0.16 10.9 3.4 0.19 10.6 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Opiods_neuropep PF01160.13 OAJ29772.1 - 0.095 12.4 0.5 0.14 11.8 0.3 1.3 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide WD40 PF00400.27 OAJ29773.1 - 3.8e-50 166.0 27.5 5.4e-11 41.9 0.8 10.9 11 0 0 11 11 11 9 WD domain, G-beta repeat Nucleoporin_N PF08801.6 OAJ29773.1 - 0.057 12.1 0.3 19 3.8 0.1 3.0 2 1 0 3 3 3 0 Nup133 N terminal like Metallopep PF12044.3 OAJ29774.1 - 1.5e-10 40.1 0.0 2.4e-09 36.1 0.0 2.0 2 0 0 2 2 2 2 Putative peptidase family Zn_clus PF00172.13 OAJ29775.1 - 0.046 13.6 7.8 0.12 12.3 5.1 1.9 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-oxoacid_dh PF00198.18 OAJ29776.1 - 4.2e-56 189.8 0.0 7.6e-55 185.6 0.0 2.4 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 OAJ29776.1 - 3.7e-19 68.1 0.1 5.7e-19 67.5 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 OAJ29776.1 - 3.9e-15 55.1 0.3 9.8e-15 53.9 0.2 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 OAJ29776.1 - 0.01 15.4 0.0 0.084 12.5 0.0 2.2 1 1 1 2 2 2 0 Biotin-lipoyl like HlyD_2 PF12700.2 OAJ29776.1 - 0.073 12.2 0.0 0.88 8.6 0.0 2.0 1 1 1 2 2 2 0 HlyD family secretion protein PYNP_C PF07831.8 OAJ29776.1 - 0.078 12.4 0.0 18 4.9 0.0 2.5 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain GCV_H PF01597.14 OAJ29776.1 - 0.2 11.3 0.1 0.36 10.5 0.1 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein RTA1 PF04479.8 OAJ29778.1 - 4.5e-35 121.1 6.4 5.9e-35 120.7 4.4 1.2 1 0 0 1 1 1 1 RTA1 like protein Claudin_2 PF13903.1 OAJ29778.1 - 1.7 8.3 9.1 0.14 11.8 0.6 2.7 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Phage_integrase PF00589.17 OAJ29779.1 - 3.1e-06 26.9 0.0 9.6e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 Phage integrase family Clathrin PF00637.15 OAJ29780.1 - 5.8e-15 55.1 0.4 4.4e-06 26.3 0.0 3.5 3 0 0 3 3 3 3 Region in Clathrin and VPS VPS11_C PF12451.3 OAJ29780.1 - 3.6e-08 33.1 0.4 3.6e-08 33.1 0.3 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 OAJ29780.1 - 0.012 15.4 6.6 0.021 14.6 4.6 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 OAJ29780.1 - 0.17 11.6 6.5 0.29 10.9 4.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAJ29780.1 - 0.44 10.6 6.1 0.78 9.8 4.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 OAJ29780.1 - 0.78 9.5 7.1 1.4 8.7 4.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 OAJ29780.1 - 1.7 8.4 5.6 3.2 7.5 3.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.20 OAJ29780.1 - 6 6.6 6.6 11 5.8 4.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_4 PF13717.1 OAJ29780.1 - 6.6 6.5 4.0 2.5 7.8 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain RVT_3 PF13456.1 OAJ29781.1 - 2.3e-06 27.2 0.2 2.1e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase-like DNA_pol_viral_C PF00336.13 OAJ29781.1 - 0.025 13.8 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Sugarporin_N PF11471.3 OAJ29781.1 - 6.8 6.4 8.9 0.93 9.1 3.0 1.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension AAA_25 PF13481.1 OAJ29782.1 - 0.0023 17.3 0.5 0.16 11.3 0.0 3.3 4 0 0 4 4 4 1 AAA domain DnaB_C PF03796.10 OAJ29782.1 - 0.06 12.2 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Band_7 PF01145.20 OAJ29783.1 - 1.7e-06 28.0 0.0 1.7e-06 28.0 0.0 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Gly-zipper_OmpA PF13436.1 OAJ29783.1 - 9.8 5.8 12.8 16 5.2 8.9 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Carn_acyltransf PF00755.15 OAJ29785.1 - 8.8e-168 559.0 0.0 1e-167 558.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Mito_carr PF00153.22 OAJ29786.1 - 1.7e-66 219.9 4.2 4e-22 77.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4017 PF13209.1 OAJ29787.1 - 0.35 10.6 3.5 0.73 9.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) TcpE PF12648.2 OAJ29787.1 - 1.5 8.9 3.8 5.3 7.2 0.1 2.9 2 1 1 3 3 3 0 TcpE family DUF3087 PF11286.3 OAJ29787.1 - 3.2 6.9 5.6 0.31 10.2 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) DUF883 PF05957.8 OAJ29788.1 - 0.035 14.5 0.8 0.035 14.5 0.5 2.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Pex14_N PF04695.8 OAJ29789.1 - 7.9 6.5 16.0 4.2 7.4 0.0 4.5 4 1 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RNA_pol_Rpb2_6 PF00562.23 OAJ29790.1 - 1e-109 366.8 0.0 1.4e-109 366.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 OAJ29790.1 - 6.4e-31 106.8 0.0 9.2e-31 106.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 OAJ29790.1 - 6.6e-24 83.4 0.0 1.7e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 OAJ29790.1 - 6.1e-23 80.5 0.0 1.4e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 OAJ29790.1 - 1.2e-19 70.4 0.0 2.8e-19 69.3 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 OAJ29790.1 - 5.5e-17 61.7 0.1 1.2e-14 54.3 0.0 3.2 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 7 DUF2058 PF09831.4 OAJ29791.1 - 0.23 11.3 4.1 0.45 10.3 2.8 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF4203 PF13886.1 OAJ29792.1 - 9.8e-31 106.8 20.5 1.3e-30 106.4 14.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Pox_A14 PF05767.7 OAJ29792.1 - 0.13 12.2 1.4 0.33 10.9 0.9 1.7 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Parvo_NS1 PF01057.12 OAJ29793.1 - 0.034 13.0 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ThuA PF06283.6 OAJ29794.1 - 1.9e-40 138.8 6.2 6.4e-30 104.4 0.2 2.9 3 0 0 3 3 3 2 Trehalose utilisation Zip PF02535.17 OAJ29794.1 - 2.1 7.2 6.1 3.1 6.6 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Bd3614_N PF14442.1 OAJ29794.1 - 5.2 7.0 9.9 2.6 8.0 0.8 2.4 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal Pkinase PF00069.20 OAJ29795.1 - 8.4e-72 241.4 0.0 1e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ29795.1 - 7.8e-29 100.5 0.1 1.2e-28 99.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ29795.1 - 1.2e-05 24.4 0.1 4.9e-05 22.4 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 OAJ29795.1 - 0.00026 20.1 0.1 0.00059 18.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ29795.1 - 0.015 15.0 0.6 0.17 11.5 0.3 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 OAJ29795.1 - 0.058 12.7 0.1 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family HAD_2 PF13419.1 OAJ29798.1 - 3.8e-18 66.3 0.0 2.8e-17 63.5 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAJ29798.1 - 6.4e-06 26.7 0.0 1.7e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAJ29798.1 - 3.9e-05 23.2 0.0 6.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like SCO1-SenC PF02630.9 OAJ29799.1 - 3.2e-53 179.9 0.0 4.5e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 OAJ29799.1 - 0.0097 15.5 0.0 0.027 14.1 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family DASH_Ask1 PF08655.5 OAJ29800.1 - 1.9e-28 98.0 0.0 3e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 OHCU_decarbox PF09349.5 OAJ29801.1 - 7.5e-25 88.0 0.0 1.6e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 OHCU decarboxylase Glyco_hydro_18 PF00704.23 OAJ29802.1 - 1.6e-58 198.7 2.4 2e-58 198.4 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MutS_V PF00488.16 OAJ29803.1 - 1.9e-61 207.4 0.0 2.9e-61 206.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAJ29803.1 - 2.3e-10 40.6 0.9 2.3e-10 40.6 0.6 2.9 2 1 1 3 3 3 1 MutS domain III AAA_29 PF13555.1 OAJ29803.1 - 0.0081 15.6 0.0 0.022 14.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 OAJ29803.1 - 0.0097 15.3 0.1 0.073 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 OAJ29803.1 - 0.068 13.0 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 OAJ29803.1 - 0.087 12.9 0.1 19 5.3 0.0 3.3 3 1 0 3 3 3 0 AAA domain COG2 PF06148.6 OAJ29803.1 - 0.17 11.7 3.8 2.3 8.0 0.2 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_23 PF13476.1 OAJ29803.1 - 0.43 10.8 3.1 0.83 9.9 0.0 2.8 4 0 0 4 4 4 0 AAA domain Ras PF00071.17 OAJ29804.1 - 3.7e-57 192.2 0.1 4.4e-57 191.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ29804.1 - 8.9e-19 68.1 0.0 1.9e-18 67.0 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 OAJ29804.1 - 3.9e-14 52.2 0.0 4.5e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ29804.1 - 9.4e-08 31.6 0.0 1.7e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ29804.1 - 2.6e-07 30.5 0.0 3.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 OAJ29804.1 - 7.1e-07 28.6 0.1 8.9e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 OAJ29804.1 - 0.00033 20.2 0.6 0.017 14.7 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 OAJ29804.1 - 0.0005 20.2 0.0 0.00097 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 OAJ29804.1 - 0.0012 18.0 0.1 0.0029 16.7 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 OAJ29804.1 - 0.0016 17.8 0.1 0.18 11.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 OAJ29804.1 - 0.0035 16.4 0.2 0.053 12.5 0.0 2.3 2 1 0 2 2 2 1 Septin AAA_16 PF13191.1 OAJ29804.1 - 0.0043 17.0 0.0 0.02 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 OAJ29804.1 - 0.0048 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 OAJ29804.1 - 0.0063 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase cobW PF02492.14 OAJ29804.1 - 0.0076 15.7 0.0 0.031 13.7 0.0 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 OAJ29804.1 - 0.01 15.2 0.1 0.018 14.5 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain SRPRB PF09439.5 OAJ29804.1 - 0.017 14.3 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 OAJ29804.1 - 0.017 14.8 0.0 0.06 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 OAJ29804.1 - 0.022 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 NTPase MobB PF03205.9 OAJ29804.1 - 0.033 13.9 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 OAJ29804.1 - 0.07 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 OAJ29804.1 - 0.097 11.9 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B FtsX PF02687.16 OAJ29805.1 - 0.017 14.8 0.8 0.036 13.8 0.6 1.5 1 0 0 1 1 1 0 FtsX-like permease family zf-P11 PF03854.9 OAJ29806.1 - 0.06 12.8 0.4 0.06 12.8 0.3 2.2 2 0 0 2 2 2 0 P-11 zinc finger ATG16 PF08614.6 OAJ29807.1 - 1.4e-45 155.5 23.5 3.4e-45 154.2 16.3 1.6 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) COMPASS-Shg1 PF05205.7 OAJ29807.1 - 0.034 14.4 3.0 0.67 10.2 2.5 2.2 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 ISG65-75 PF11727.3 OAJ29807.1 - 0.05 12.6 2.3 0.083 11.9 1.6 1.5 1 0 0 1 1 1 0 Invariant surface glycoprotein Mer2 PF09074.5 OAJ29807.1 - 0.063 13.2 7.6 0.13 12.1 5.3 1.5 1 0 0 1 1 1 0 Mer2 ORF6N PF10543.4 OAJ29807.1 - 0.068 13.2 2.0 0.2 11.7 0.4 2.3 2 1 1 3 3 3 0 ORF6N domain LURAP PF14854.1 OAJ29807.1 - 0.074 12.7 2.4 0.11 12.2 0.1 2.4 1 1 1 3 3 3 0 Leucine rich adaptor protein Herpes_capsid PF06112.6 OAJ29807.1 - 0.32 11.0 5.0 0.18 11.8 1.4 2.0 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein RAP1 PF07218.6 OAJ29807.1 - 0.42 8.6 3.1 0.23 9.5 0.9 1.4 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FlgN PF05130.7 OAJ29807.1 - 0.58 10.4 23.6 0.19 11.9 12.0 2.4 1 1 1 2 2 2 0 FlgN protein Fib_alpha PF08702.5 OAJ29807.1 - 3 7.9 12.4 0.14 12.2 4.0 2.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family ATP-synt_ab PF00006.20 OAJ29808.1 - 1.2e-109 364.8 0.0 1.8e-109 364.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 OAJ29808.1 - 8.1e-21 74.6 0.2 1.7e-20 73.5 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 OAJ29808.1 - 1.1e-13 51.1 3.8 2.8e-13 49.8 2.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 OAJ29808.1 - 0.041 13.7 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Methyltransf_12 PF08242.7 OAJ29809.1 - 0.016 15.6 0.0 0.058 13.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain LRS4 PF10422.4 OAJ29809.1 - 0.22 10.8 3.3 0.3 10.4 2.3 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 MRP-S31 PF15433.1 OAJ29811.1 - 0.012 15.0 13.0 0.013 14.9 9.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF2722 PF10846.3 OAJ29811.1 - 0.12 11.3 27.9 0.15 11.0 19.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med15 PF09606.5 OAJ29811.1 - 0.69 8.0 33.1 0.83 7.7 22.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SprA-related PF12118.3 OAJ29811.1 - 0.94 8.7 28.0 1 8.6 19.4 1.1 1 0 0 1 1 1 0 SprA-related family TFIIA PF03153.8 OAJ29811.1 - 1.1 9.0 26.5 1.5 8.6 18.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FLO_LFY PF01698.11 OAJ29811.1 - 1.6 7.5 5.1 1.7 7.3 3.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein RR_TM4-6 PF06459.7 OAJ29811.1 - 2.4 7.9 8.4 3.1 7.5 5.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S64 PF08192.6 OAJ29811.1 - 3.4 5.9 14.4 3.8 5.7 10.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 Apt1 PF10351.4 OAJ29811.1 - 4.4 6.0 10.7 5.6 5.6 7.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.2 OAJ29811.1 - 7.1 4.1 13.9 7.4 4.1 9.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2486 PF10667.4 OAJ29811.1 - 7.1 7.0 14.0 8.8 6.7 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) DUF4106 PF13388.1 OAJ29811.1 - 8.3 5.2 25.1 12 4.6 17.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Rhodanese PF00581.15 OAJ29813.1 - 9.3e-08 32.4 0.0 1.3e-07 31.9 0.0 1.3 1 1 0 1 1 1 1 Rhodanese-like domain ECH PF00378.15 OAJ29814.1 - 8.2e-17 61.1 0.0 1.6e-16 60.1 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pkinase PF00069.20 OAJ29816.1 - 8.3e-65 218.5 0.0 1.3e-34 119.5 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ29816.1 - 1.6e-31 109.3 0.0 1e-15 57.5 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 OAJ29816.1 - 1.4e-17 63.6 0.0 3.4e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 OAJ29816.1 - 1.1e-13 50.9 0.8 5e-13 48.7 0.0 2.2 2 0 0 2 2 2 1 Histidyl-tRNA synthetase HGTP_anticodon2 PF12745.2 OAJ29816.1 - 2.2e-13 49.9 2.3 3.1e-13 49.4 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs APH PF01636.18 OAJ29816.1 - 1.2e-06 28.5 0.0 1.2e-06 28.5 0.0 3.5 4 1 0 4 4 4 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ29816.1 - 5.3e-05 22.3 1.5 0.00034 19.6 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Methyltransf_16 PF10294.4 OAJ29817.1 - 4.9e-18 65.1 0.0 1.7e-16 60.1 0.0 2.3 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 OAJ29817.1 - 2.7e-05 24.7 0.0 6.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ29817.1 - 0.0017 18.4 0.1 0.0049 16.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 OAJ29817.1 - 0.0029 17.0 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 OAJ29817.1 - 0.0074 16.7 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ29817.1 - 0.056 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ29817.1 - 0.063 13.7 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain COP-gamma_platf PF08752.5 OAJ29817.1 - 0.13 12.0 0.1 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Coatomer gamma subunit appendage platform subdomain DREV PF05219.7 OAJ29817.1 - 0.2 10.5 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase ING PF12998.2 OAJ29819.1 - 2.4e-10 40.6 0.0 4.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 OAJ29819.1 - 3.2e-09 36.3 9.0 5.3e-09 35.6 6.2 1.4 1 0 0 1 1 1 1 PHD-finger DDHD PF02862.12 OAJ29821.1 - 5.6e-35 121.1 0.0 5.6e-35 121.1 0.0 3.5 2 1 0 2 2 2 1 DDHD domain Abhydrolase_5 PF12695.2 OAJ29821.1 - 0.072 12.8 0.0 0.5 10.1 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family CENP-B_dimeris PF09026.5 OAJ29821.1 - 2.3 8.4 34.8 2.4 8.4 2.8 4.5 4 0 0 4 4 4 0 Centromere protein B dimerisation domain DnaJ PF00226.26 OAJ29822.1 - 1.5e-18 66.3 0.3 2.8e-18 65.4 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DUF3166 PF11365.3 OAJ29823.1 - 0.1 13.0 0.4 0.21 12.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3166) Fic_N PF13784.1 OAJ29825.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Fic/DOC family N-terminal MAGP PF05507.6 OAJ29825.1 - 0.16 11.7 0.3 0.53 10.1 0.0 2.0 2 0 0 2 2 2 0 Microfibril-associated glycoprotein (MAGP) Abhydrolase_6 PF12697.2 OAJ29826.1 - 1.1e-07 31.9 0.6 2.3e-07 30.9 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ29826.1 - 4.2e-05 23.3 0.1 6.9e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 OAJ29826.1 - 0.014 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF1749 PF08538.5 OAJ29826.1 - 0.034 13.0 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) YL1 PF05764.8 OAJ29828.1 - 0.0029 17.2 4.3 0.004 16.7 3.0 1.2 1 0 0 1 1 1 1 YL1 nuclear protein SURF1 PF02104.10 OAJ29828.1 - 0.01 15.6 0.1 0.016 15.0 0.1 1.2 1 0 0 1 1 1 0 SURF1 family OrfB_IS605 PF01385.14 OAJ29829.1 - 0.13 11.6 8.3 0.15 11.3 0.7 2.5 1 1 1 2 2 2 0 Probable transposase ADH_zinc_N PF00107.21 OAJ29831.1 - 5.9e-12 45.2 0.2 1.2e-11 44.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ29831.1 - 3.1e-10 39.7 1.1 6.3e-09 35.5 0.7 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 OAJ29831.1 - 0.02 15.7 0.0 0.04 14.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RabGAP-TBC PF00566.13 OAJ29833.1 - 2e-19 69.9 0.0 5.1e-19 68.5 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PARP PF00644.15 OAJ29834.1 - 9.3e-06 25.2 0.2 6.4e-05 22.4 0.1 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain bZIP_1 PF00170.16 OAJ29836.1 - 4.5e-06 26.5 3.6 1.3e-05 25.0 2.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAJ29836.1 - 5e-05 23.0 4.7 0.00012 21.7 3.3 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Herpes_BLRF2 PF05812.7 OAJ29836.1 - 0.00027 20.7 0.3 0.00067 19.4 0.2 1.7 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein Allexi_40kDa PF05549.6 OAJ29836.1 - 0.011 15.0 0.6 0.038 13.3 0.4 1.9 1 0 0 1 1 1 0 Allexivirus 40kDa protein Myosin_tail_1 PF01576.14 OAJ29836.1 - 0.012 13.3 2.0 0.017 12.8 1.4 1.1 1 0 0 1 1 1 0 Myosin tail DivIC PF04977.10 OAJ29836.1 - 0.28 10.7 0.4 0.58 9.6 0.3 1.5 1 0 0 1 1 1 0 Septum formation initiator PALP PF00291.20 OAJ29837.1 - 1.6e-48 165.5 2.7 6.7e-48 163.4 1.9 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.10 OAJ29837.1 - 0.058 12.9 0.4 0.13 11.8 0.3 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Pkinase PF00069.20 OAJ29838.1 - 1.1e-59 201.7 0.0 1.4e-39 135.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ29838.1 - 6.6e-26 90.9 0.0 8.3e-21 74.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 OAJ29838.1 - 5.9e-09 35.9 0.1 1e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 OAJ29838.1 - 5.7e-07 28.7 0.4 1.2e-05 24.4 0.0 2.4 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 OAJ29838.1 - 0.00098 18.9 0.0 0.017 14.8 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ29838.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PAS_4 PF08448.5 OAJ29838.1 - 0.017 15.1 0.0 0.06 13.3 0.0 1.9 1 0 0 1 1 1 0 PAS fold Kdo PF06293.9 OAJ29838.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OKR_DC_1_N PF03709.10 OAJ29838.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Glyco_transf_90 PF05686.7 OAJ29839.1 - 1.2e-25 90.0 6.6 1.1e-22 80.2 4.6 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF3533 PF12051.3 OAJ29840.1 - 4.1e-75 252.9 11.1 4.9e-75 252.6 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.2 OAJ29840.1 - 4.1e-05 22.7 17.0 7.8e-05 21.8 11.8 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein Ibs_toxin PF13956.1 OAJ29840.1 - 0.11 12.3 0.3 0.11 12.3 0.2 2.4 2 0 0 2 2 2 0 Toxin Ibs, type I toxin-antitoxin system HAD_2 PF13419.1 OAJ29841.1 - 1.6e-14 54.5 0.0 4.5e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAJ29841.1 - 2.2e-12 47.8 1.0 4.5e-12 46.8 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAJ29841.1 - 2.9e-07 30.0 0.0 7.3e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 OAJ29841.1 - 0.0097 16.0 0.0 0.023 14.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GDPD PF03009.12 OAJ29842.1 - 1.2e-34 120.0 1.6 3.4e-34 118.5 1.1 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 OAJ29842.1 - 0.0024 18.0 2.7 0.0024 18.0 1.8 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DUF2905 PF11146.3 OAJ29843.1 - 2.3 8.1 5.5 0.22 11.4 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) DUF3533 PF12051.3 OAJ29844.1 - 4.4e-82 275.8 18.2 5.2e-82 275.6 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Cytochrom_B561 PF03188.11 OAJ29845.1 - 1.3e-08 34.7 9.8 1.3e-08 34.7 6.8 1.9 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.12 OAJ29845.1 - 0.0012 18.7 0.2 0.0026 17.6 0.1 1.6 1 1 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 OAJ29845.1 - 0.32 10.5 8.6 0.11 12.1 3.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF4173 PF13777.1 OAJ29845.1 - 3.4 6.9 6.1 0.76 9.0 0.3 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4173) zf-BED PF02892.10 OAJ29846.1 - 0.047 13.4 0.2 0.088 12.5 0.1 1.4 1 0 0 1 1 1 0 BED zinc finger MULE PF10551.4 OAJ29849.1 - 1.2e-14 54.2 0.0 3.4e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 MULE transposase domain FAR1 PF03101.10 OAJ29849.1 - 8.4e-06 26.2 5.9 1.1e-05 25.8 0.5 3.1 3 0 0 3 3 3 1 FAR1 DNA-binding domain AFT PF08731.6 OAJ29849.1 - 0.0013 18.9 0.1 0.003 17.7 0.1 1.6 1 0 0 1 1 1 1 Transcription factor AFT PEX11 PF05648.9 OAJ29850.1 - 1.8e-62 210.5 2.1 2e-62 210.3 1.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) FTCD_C PF04961.7 OAJ29850.1 - 0.026 13.9 1.3 0.1 12.0 0.4 2.0 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase DNApol3-delta_C PF09115.5 OAJ29850.1 - 0.083 12.9 0.1 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal CPSF100_C PF13299.1 OAJ29851.1 - 3.2e-26 92.4 0.0 1.5e-25 90.2 0.0 2.2 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 OAJ29851.1 - 2.3e-16 59.8 0.0 4.4e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain RXT2_N PF08595.6 OAJ29851.1 - 2.1 8.1 4.4 24 4.6 0.1 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Acyltransferase PF01553.16 OAJ29852.1 - 1e-34 118.7 0.0 1.5e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Pex26 PF07163.7 OAJ29853.1 - 0.019 13.8 0.7 0.028 13.3 0.5 1.3 1 0 0 1 1 1 0 Pex26 protein DnaJ PF00226.26 OAJ29855.1 - 3.2e-21 74.8 0.4 6e-21 73.9 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain LMBR1 PF04791.11 OAJ29855.1 - 0.22 10.0 1.1 0.23 9.9 0.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF966 PF06136.8 OAJ29855.1 - 1.4 8.3 8.8 1.8 7.9 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF202 PF02656.10 OAJ29856.1 - 1.1e-12 48.0 5.4 1.1e-12 48.0 3.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) LHC PF00556.15 OAJ29856.1 - 0.078 12.8 0.2 0.078 12.8 0.2 2.3 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit DUF2615 PF11027.3 OAJ29856.1 - 0.34 10.8 0.1 0.34 10.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DUF2207 PF09972.4 OAJ29856.1 - 0.41 9.1 2.6 0.18 10.3 0.6 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2673 PF10880.3 OAJ29857.1 - 0.027 14.5 0.0 0.03 14.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) DASH_Spc19 PF08287.6 OAJ29858.1 - 0.0026 17.3 0.1 0.0057 16.2 0.0 1.6 2 0 0 2 2 2 1 Spc19 DUF3757 PF12582.3 OAJ29858.1 - 0.12 12.6 0.1 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3757) DUF1635 PF07795.6 OAJ29858.1 - 0.15 11.4 1.5 0.16 11.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF913 PF06025.7 OAJ29859.1 - 9.3e-92 307.6 0.0 9.3e-92 307.6 0.0 4.4 5 0 0 5 5 5 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 OAJ29859.1 - 3.5e-71 240.2 0.1 1.2e-70 238.4 0.1 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 OAJ29859.1 - 7.7e-25 86.9 2.8 5.7e-24 84.1 1.9 2.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) UBA PF00627.26 OAJ29859.1 - 1e-09 37.9 0.1 3e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Oxysterol_BP PF01237.13 OAJ29861.1 - 8.2e-85 284.3 0.0 1e-84 284.1 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DUF2673 PF10880.3 OAJ29862.1 - 0.018 15.0 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) IGPD PF00475.13 OAJ29863.1 - 4.1e-60 201.8 0.8 5e-60 201.5 0.3 1.3 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase DUF2917 PF11142.3 OAJ29863.1 - 0.1 11.7 0.1 0.35 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2917) FSH1 PF03959.8 OAJ29864.1 - 1.5e-53 181.3 0.0 1.8e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 OAJ29864.1 - 1.4e-07 31.5 1.2 2.6e-05 24.1 0.0 2.4 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ29864.1 - 4.7e-05 23.1 0.0 6.9e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAJ29864.1 - 0.0024 17.3 0.1 0.025 14.0 0.1 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.13 OAJ29864.1 - 0.019 14.2 0.1 0.078 12.2 0.1 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 OAJ29864.1 - 0.034 13.7 0.0 0.73 9.3 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.6 OAJ29864.1 - 0.13 11.9 0.0 5.8 6.5 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal WD40 PF00400.27 OAJ29865.1 - 1.6e-18 65.7 5.7 1.3e-07 31.2 0.1 5.9 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF3639 PF12341.3 OAJ29865.1 - 0.0017 18.2 2.4 0.0067 16.3 0.7 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) BBS2_Mid PF14783.1 OAJ29865.1 - 0.2 11.4 0.0 0.68 9.7 0.0 1.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Bromodomain PF00439.20 OAJ29866.1 - 6.5e-18 64.4 0.0 1.3e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Cut8_N PF14482.1 OAJ29866.1 - 0.75 9.8 7.1 12 5.9 0.7 4.0 3 0 0 3 3 3 0 Cut8 proteasome-binding domain Ferrochelatase PF00762.14 OAJ29867.1 - 4.2e-104 347.9 0.0 5e-104 347.6 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.12 OAJ29867.1 - 0.016 15.3 0.0 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 CbiX Piwi PF02171.12 OAJ29868.1 - 1.4e-77 260.6 0.0 2e-77 260.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 OAJ29868.1 - 2e-19 69.2 0.0 3.9e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 OAJ29868.1 - 1.3e-13 50.0 0.0 3e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) BC10 PF06726.7 OAJ29869.1 - 9.6e-12 44.7 9.2 1.8e-11 43.8 6.4 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 RRXRR PF14239.1 OAJ29869.1 - 0.24 10.8 2.4 0.39 10.1 1.7 1.2 1 0 0 1 1 1 0 RRXRR protein FlxA PF14282.1 OAJ29869.1 - 0.64 10.0 13.2 1.8 8.5 9.1 1.8 1 0 0 1 1 1 0 FlxA-like protein Malic_M PF03949.10 OAJ29870.1 - 1.8e-84 283.2 0.0 2.4e-84 282.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 OAJ29870.1 - 1.6e-63 213.5 0.0 3e-63 212.6 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Peptidase_A22B PF04258.8 OAJ29873.1 - 5.9e-70 236.0 7.2 7.6e-70 235.7 5.0 1.1 1 0 0 1 1 1 1 Signal peptide peptidase CENP-B_dimeris PF09026.5 OAJ29873.1 - 0.00017 21.7 0.6 0.0013 18.9 0.0 2.2 2 0 0 2 2 2 1 Centromere protein B dimerisation domain FAM176 PF14851.1 OAJ29873.1 - 0.3 10.7 0.0 0.3 10.7 0.0 2.1 2 1 0 2 2 2 0 FAM176 family zf-C2H2_4 PF13894.1 OAJ29874.1 - 2.1e-10 40.1 6.3 0.00012 22.1 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 OAJ29874.1 - 2.1e-09 37.1 9.7 0.00039 20.5 0.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAJ29874.1 - 3e-08 33.5 4.9 2e-06 27.8 0.5 3.0 2 0 0 2 2 2 2 Zinc-finger double domain RRM_1 PF00076.17 OAJ29875.1 - 1.3e-12 47.1 0.0 2.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ29875.1 - 2.5e-10 40.2 0.0 4.2e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ29875.1 - 4.1e-07 29.7 0.0 6.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 OAJ29875.1 - 8.8e-07 29.2 2.8 8.8e-07 29.2 2.0 2.9 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Smg4_UPF3 PF03467.10 OAJ29875.1 - 0.072 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family Methyltransf_23 PF13489.1 OAJ29876.1 - 2.1e-09 37.3 0.0 7.1e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ29876.1 - 5e-08 33.3 0.0 1.3e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ29876.1 - 5.4e-05 23.4 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ29876.1 - 0.00069 19.6 0.0 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ29876.1 - 0.00096 18.5 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 OAJ29876.1 - 0.0045 17.5 0.0 0.0073 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ29876.1 - 0.0047 16.5 0.0 0.0094 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ29876.1 - 0.027 14.9 0.0 0.075 13.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain FmrO PF07091.6 OAJ29876.1 - 0.052 12.5 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Saccharop_dh PF03435.13 OAJ29876.1 - 0.053 12.4 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Med12 PF09497.5 OAJ29876.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Transcription mediator complex subunit Med12 Suf PF05843.9 OAJ29877.1 - 2.9e-79 266.7 0.0 2.3e-76 257.1 0.0 3.9 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 OAJ29877.1 - 9.2e-07 28.9 1.8 19 6.2 0.0 7.4 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ29877.1 - 2.6e-05 24.4 0.0 1.1 9.6 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat AKAP95 PF04988.7 OAJ29878.1 - 0.018 14.8 0.3 0.033 13.9 0.2 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Phage_Gp23 PF10669.4 OAJ29878.1 - 0.48 10.5 6.1 0.18 11.8 2.3 1.7 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DivIVA PF05103.8 OAJ29878.1 - 4.2 7.4 10.9 0.3 11.1 3.9 1.7 2 0 0 2 2 2 0 DivIVA protein DUF2457 PF10446.4 OAJ29879.1 - 0.00062 18.6 4.7 0.00076 18.3 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CobT PF06213.7 OAJ29879.1 - 0.012 14.8 0.4 0.016 14.3 0.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Phytochelatin_C PF09328.5 OAJ29879.1 - 0.049 13.1 0.0 0.061 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) Neisseria_TspB PF05616.8 OAJ29879.1 - 0.062 11.6 0.7 0.08 11.3 0.5 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein PBP1_TM PF14812.1 OAJ29879.1 - 1.2 9.5 9.7 2.3 8.5 6.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SDH_alpha PF03313.10 OAJ29880.1 - 3.3e-93 311.8 1.4 5.6e-93 311.0 1.0 1.3 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 OAJ29880.1 - 1.4e-51 174.6 0.0 2.6e-51 173.7 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain HEAT PF02985.17 OAJ29881.1 - 6.3e-11 41.4 16.0 0.027 14.5 0.0 9.8 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 OAJ29881.1 - 3.2e-10 40.1 16.1 0.0018 18.5 0.0 6.3 2 2 3 5 5 5 4 HEAT repeats Adaptin_N PF01602.15 OAJ29881.1 - 0.0014 17.0 3.3 0.079 11.2 0.0 2.8 3 0 0 3 3 3 2 Adaptin N terminal region DUF4042 PF13251.1 OAJ29881.1 - 0.73 9.2 0.5 24 4.3 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4042) Atg8 PF02991.11 OAJ29882.1 - 3.9e-52 174.5 0.2 4.6e-52 174.3 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 OAJ29882.1 - 5.2e-07 29.7 0.0 6.5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 NAPRTase PF04095.11 OAJ29883.1 - 2.7e-41 141.4 0.2 1.5e-16 60.4 0.0 3.2 3 0 0 3 3 3 3 Nicotinate phosphoribosyltransferase (NAPRTase) family Mt_ATP-synt_D PF05873.7 OAJ29884.1 - 6.7e-10 38.8 0.5 8.4e-10 38.5 0.3 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) MiaE_2 PF13794.1 OAJ29884.1 - 0.013 15.0 0.2 0.022 14.2 0.1 1.4 1 1 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like DUF1366 PF07104.6 OAJ29884.1 - 0.015 14.9 2.8 0.028 14.0 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) DUF2408 PF10303.4 OAJ29884.1 - 0.05 13.7 0.8 0.087 12.9 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) HsbA PF12296.3 OAJ29884.1 - 0.076 12.8 1.9 0.16 11.8 0.4 1.9 1 1 1 2 2 2 0 Hydrophobic surface binding protein A Cauli_AT PF03233.8 OAJ29884.1 - 0.093 12.4 1.3 0.16 11.6 0.9 1.4 1 0 0 1 1 1 0 Aphid transmission protein MbeB_N PF04837.7 OAJ29884.1 - 0.26 11.4 3.3 0.17 12.0 0.6 1.9 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Pribosyltran PF00156.22 OAJ29885.1 - 3.1e-10 39.8 0.0 5.3e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF3628 PF12300.3 OAJ29886.1 - 0.0032 17.5 2.2 0.14 12.1 3.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3628) Lant_dehyd_C PF04738.8 OAJ29886.1 - 0.024 12.8 0.1 0.031 12.5 0.1 1.1 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus DUF4088 PF13317.1 OAJ29886.1 - 0.049 12.9 0.6 0.063 12.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) DUF615 PF04751.9 OAJ29886.1 - 0.75 9.4 5.2 0.4 10.3 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF615) Cys_Met_Meta_PP PF01053.15 OAJ29887.1 - 6.2e-119 396.7 0.0 2.2e-118 394.9 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 OAJ29887.1 - 2.7e-16 59.3 1.9 1.3e-15 57.2 1.1 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 OAJ29887.1 - 6.4e-05 23.0 0.3 0.00079 19.5 0.1 2.9 1 1 1 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 OAJ29887.1 - 0.0063 15.7 0.3 0.013 14.7 0.2 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Aminotran_1_2 PF00155.16 OAJ29887.1 - 0.066 12.1 0.5 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class I and II SPT16 PF08644.6 OAJ29888.1 - 6.5e-51 172.1 0.1 2.2e-50 170.4 0.0 2.0 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 OAJ29888.1 - 4e-40 137.0 0.8 1.1e-39 135.5 0.6 1.8 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 OAJ29888.1 - 1.4e-22 80.2 0.0 2.8e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 OAJ29888.1 - 1.8e-20 72.6 1.2 5.1e-20 71.2 0.0 2.4 4 0 0 4 4 4 1 Histone chaperone Rttp106-like Zip PF02535.17 OAJ29889.1 - 0.018 14.0 1.2 0.024 13.6 0.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 OAJ29889.1 - 6.5 6.0 15.4 11 5.2 10.6 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Paramyx_P_V_C PF03210.8 OAJ29890.1 - 0.00079 19.3 0.8 0.0015 18.4 0.6 1.4 1 0 0 1 1 1 1 Paramyxovirus P/V phosphoprotein C-terminal Cytochrom_C1 PF02167.10 OAJ29890.1 - 0.017 14.7 0.1 0.02 14.5 0.1 1.1 1 0 0 1 1 1 0 Cytochrome C1 family T2SM PF04612.7 OAJ29890.1 - 0.039 13.7 6.1 0.067 12.9 4.2 1.4 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M Cluap1 PF10234.4 OAJ29890.1 - 0.045 12.9 5.4 0.053 12.7 3.7 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 HAUS6_N PF14661.1 OAJ29890.1 - 0.066 12.5 5.1 0.073 12.4 3.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Laminin_II PF06009.7 OAJ29890.1 - 0.066 12.9 4.3 0.12 12.1 2.9 1.5 1 1 0 1 1 1 0 Laminin Domain II End3 PF12761.2 OAJ29890.1 - 0.077 12.6 2.4 0.082 12.5 1.6 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 PFL PF02901.10 OAJ29890.1 - 0.098 11.0 7.5 0.12 10.7 5.2 1.0 1 0 0 1 1 1 0 Pyruvate formate lyase MAP7 PF05672.6 OAJ29890.1 - 0.26 10.6 7.1 0.32 10.3 5.0 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family UPF0122 PF04297.9 OAJ29890.1 - 0.34 10.9 4.1 0.48 10.4 2.6 1.4 1 1 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like TarH PF02203.10 OAJ29890.1 - 0.36 10.6 5.4 0.44 10.3 3.7 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue Cache_3 PF14827.1 OAJ29890.1 - 0.49 10.2 2.1 0.81 9.6 1.4 1.5 1 1 0 1 1 1 0 Sensory domain of two-component sensor kinase DUF342 PF03961.8 OAJ29890.1 - 0.58 8.5 3.1 0.66 8.3 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Eapp_C PF10238.4 OAJ29890.1 - 0.69 9.8 5.5 2 8.2 3.8 1.9 1 1 0 1 1 1 0 E2F-associated phosphoprotein IBN_N PF03810.14 OAJ29891.1 - 1.6e-14 53.5 0.0 7.4e-12 45.0 0.0 3.1 3 0 0 3 3 3 2 Importin-beta N-terminal domain Cse1 PF08506.5 OAJ29891.1 - 1.1e-08 34.0 0.0 3.3e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.7 OAJ29891.1 - 1.5e-05 24.9 1.3 0.00053 19.9 0.0 3.0 2 1 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.1 OAJ29891.1 - 0.0066 16.7 8.2 0.17 12.2 0.0 4.1 5 0 0 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.2 OAJ29891.1 - 0.019 15.3 0.1 0.7 10.3 0.0 3.7 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region HTH_psq PF05225.11 OAJ29891.1 - 0.055 13.0 0.2 0.15 11.6 0.1 1.8 1 0 0 1 1 1 0 helix-turn-helix, Psq domain AAA PF00004.24 OAJ29892.1 - 1e-96 320.1 0.0 2.1e-47 160.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 OAJ29892.1 - 1.6e-22 79.2 0.1 7e-22 77.1 0.0 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 OAJ29892.1 - 8.6e-16 57.6 0.0 2e-05 23.7 0.0 4.0 4 1 0 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 OAJ29892.1 - 2.4e-13 50.1 0.0 1.6e-06 28.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.9 OAJ29892.1 - 4.6e-13 49.4 0.0 3.6e-07 30.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 OAJ29892.1 - 2.5e-12 46.7 0.4 6.1e-06 25.9 0.0 3.9 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 OAJ29892.1 - 1.6e-11 45.0 0.0 0.00054 20.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAJ29892.1 - 3.9e-11 43.2 0.2 0.0016 18.5 0.0 4.0 2 2 1 3 3 2 2 AAA domain CDC48_2 PF02933.12 OAJ29892.1 - 3.6e-10 39.3 0.0 7.7e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.8 OAJ29892.1 - 2.3e-09 36.4 0.0 0.0013 17.4 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 OAJ29892.1 - 4.9e-09 36.4 0.0 0.0065 16.4 0.0 3.3 2 2 0 2 2 2 2 AAA ATPase domain Vps4_C PF09336.5 OAJ29892.1 - 1e-08 34.9 0.1 5.3e-08 32.6 0.0 2.2 2 1 1 3 3 1 1 Vps4 C terminal oligomerisation domain Zeta_toxin PF06414.7 OAJ29892.1 - 1e-08 34.5 0.0 0.005 15.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 OAJ29892.1 - 3.6e-08 33.0 0.0 0.0032 16.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 OAJ29892.1 - 3.8e-08 32.7 0.4 0.0022 17.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 OAJ29892.1 - 4.3e-08 32.7 3.1 0.0031 16.9 0.0 4.0 3 2 1 5 5 4 2 AAA domain AAA_14 PF13173.1 OAJ29892.1 - 6.1e-08 32.6 0.0 0.0064 16.3 0.0 3.2 4 0 0 4 4 2 2 AAA domain AAA_19 PF13245.1 OAJ29892.1 - 3.4e-07 29.9 1.7 0.015 15.0 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain RNA_helicase PF00910.17 OAJ29892.1 - 1.2e-06 28.5 0.0 0.014 15.5 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 OAJ29892.1 - 3.1e-06 27.2 0.0 0.058 13.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 OAJ29892.1 - 4e-06 27.1 0.0 0.042 14.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 OAJ29892.1 - 4.9e-06 25.8 1.0 0.86 8.6 0.0 3.5 2 1 1 3 3 3 2 KaiC Parvo_NS1 PF01057.12 OAJ29892.1 - 5.2e-06 25.5 0.2 0.0053 15.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 OAJ29892.1 - 7.3e-06 25.9 0.0 0.0079 16.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF815 PF05673.8 OAJ29892.1 - 7.5e-06 25.0 0.0 0.0021 17.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 OAJ29892.1 - 1.6e-05 24.6 0.1 0.067 12.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.22 OAJ29892.1 - 1.6e-05 25.2 0.0 0.11 12.7 0.0 3.6 3 1 0 3 3 2 1 ABC transporter Sigma54_activat PF00158.21 OAJ29892.1 - 1.7e-05 24.3 0.0 0.36 10.2 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 OAJ29892.1 - 2.4e-05 24.4 0.0 0.17 11.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 OAJ29892.1 - 4.9e-05 22.6 0.2 0.31 10.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.7 OAJ29892.1 - 5.1e-05 22.9 0.1 0.07 12.7 0.0 3.4 3 0 0 3 3 3 1 NACHT domain Arch_ATPase PF01637.13 OAJ29892.1 - 0.00012 21.8 0.5 2.1 7.9 0.0 3.6 3 1 1 4 4 3 1 Archaeal ATPase AAA_3 PF07726.6 OAJ29892.1 - 0.00014 21.4 0.0 0.42 10.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 OAJ29892.1 - 0.00016 21.3 0.0 0.57 9.7 0.0 2.7 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_11 PF13086.1 OAJ29892.1 - 0.00043 19.9 0.0 0.81 9.2 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 OAJ29892.1 - 0.0006 19.4 0.0 0.91 9.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 OAJ29892.1 - 0.00078 19.0 0.0 0.13 11.7 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 OAJ29892.1 - 0.002 17.6 1.1 1.2 8.5 0.0 3.9 3 1 1 4 4 4 1 AAA-like domain NB-ARC PF00931.17 OAJ29892.1 - 0.0025 16.7 0.1 0.24 10.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 OAJ29892.1 - 0.0027 17.4 0.2 0.75 9.4 0.0 3.5 3 0 0 3 3 3 1 NTPase DUF2075 PF09848.4 OAJ29892.1 - 0.0028 16.6 0.8 0.9 8.4 0.0 2.6 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 OAJ29892.1 - 0.0078 15.1 0.0 0.23 10.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein IPT PF01745.11 OAJ29892.1 - 0.021 13.9 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Molydop_binding PF01568.16 OAJ29892.1 - 0.022 14.5 0.3 0.86 9.4 0.0 3.1 2 1 1 3 3 3 0 Molydopterin dinucleotide binding domain UPF0079 PF02367.12 OAJ29892.1 - 0.026 14.1 0.1 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 OAJ29892.1 - 0.038 13.2 0.0 4.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 KAP_NTPase PF07693.9 OAJ29892.1 - 0.039 12.9 0.0 0.75 8.7 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain ATP-synt_ab PF00006.20 OAJ29892.1 - 0.048 13.1 0.1 3.7 7.0 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DNA_ligase_A_C PF04679.10 OAJ29892.1 - 0.054 13.9 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region AFG1_ATPase PF03969.11 OAJ29892.1 - 0.074 11.8 0.0 7.7 5.2 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase MobB PF03205.9 OAJ29892.1 - 0.093 12.4 0.4 5.3 6.7 0.0 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 OAJ29892.1 - 0.1 12.8 0.0 1 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 OAJ29892.1 - 0.1 12.4 0.8 6.9 6.5 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase UFD1 PF03152.9 OAJ29892.1 - 0.14 11.2 0.0 0.33 10.0 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Pinin_SDK_memA PF04696.8 OAJ29893.1 - 8.1e-08 31.9 5.0 8.1e-08 31.9 3.5 3.1 3 0 0 3 3 3 2 pinin/SDK/memA/ protein conserved region Mei4 PF13971.1 OAJ29893.1 - 0.056 12.3 0.6 0.15 11.0 0.1 1.7 2 0 0 2 2 2 0 Meiosis-specific protein Mei4 DUF2884 PF11101.3 OAJ29893.1 - 0.68 9.2 7.5 1.8 7.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Pkinase PF00069.20 OAJ29894.1 - 5.9e-38 130.4 0.0 1.3e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ29894.1 - 1.8e-10 40.3 0.0 2.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinetochor_Ybp2 PF08568.5 OAJ29894.1 - 4.2e-09 35.2 0.0 3.1e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin APH PF01636.18 OAJ29894.1 - 2e-05 24.4 0.0 9.5e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAJ29894.1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase PP2C PF00481.16 OAJ29895.1 - 3.4e-82 275.6 0.0 6.9e-82 274.6 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SNF2_N PF00176.18 OAJ29897.1 - 1.4e-63 214.4 1.0 3.5e-36 124.5 0.1 3.0 3 0 0 3 3 3 3 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ29897.1 - 3.6e-10 39.5 0.0 7.3e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SDA1 PF05285.7 OAJ29897.1 - 0.15 11.3 25.0 0.062 12.5 7.7 2.6 3 0 0 3 3 3 0 SDA1 DUF2890 PF11081.3 OAJ29897.1 - 1.8 8.5 17.2 0.23 11.4 5.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) BUD22 PF09073.5 OAJ29897.1 - 5.3 6.0 29.5 3.4 6.6 5.9 2.2 2 0 0 2 2 2 0 BUD22 PPP4R2 PF09184.6 OAJ29897.1 - 8.9 5.7 23.6 0.31 10.5 5.4 2.4 2 0 0 2 2 2 0 PPP4R2 Cu-oxidase_3 PF07732.10 OAJ29898.1 - 2.2e-37 127.4 10.7 3e-36 123.7 2.4 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAJ29898.1 - 1.7e-34 118.2 6.2 1.7e-30 105.3 0.0 3.9 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 OAJ29898.1 - 3.7e-24 85.4 0.0 9.4e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase MFS_1 PF07690.11 OAJ29899.1 - 7.6e-29 100.5 30.9 9.9e-29 100.1 21.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Cu-oxidase_3 PF07732.10 OAJ29900.1 - 1.4e-38 131.2 2.6 1.4e-38 131.2 1.8 3.4 4 1 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAJ29900.1 - 5.5e-35 119.8 11.6 3e-33 114.2 0.4 3.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 OAJ29900.1 - 4.6e-30 104.6 0.3 3.6e-28 98.4 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase Nucleoplasmin PF03066.10 OAJ29901.1 - 0.0092 15.5 2.7 0.016 14.7 1.9 1.3 1 0 0 1 1 1 1 Nucleoplasmin Senescence_reg PF04520.8 OAJ29901.1 - 0.02 15.4 2.9 0.02 15.4 2.0 1.9 2 0 0 2 2 2 0 Senescence regulator PBP1_TM PF14812.1 OAJ29901.1 - 0.16 12.3 12.7 0.034 14.4 5.7 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 OAJ29901.1 - 0.37 8.6 1.8 0.46 8.3 1.2 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 OAJ29901.1 - 0.39 10.3 4.5 0.66 9.6 3.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein gpUL132 PF11359.3 OAJ29901.1 - 0.62 9.3 3.0 1.2 8.3 2.1 1.5 1 0 0 1 1 1 0 Glycoprotein UL132 PGA2 PF07543.7 OAJ29901.1 - 1.7 8.4 4.0 3.2 7.5 2.8 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Sigma70_ner PF04546.8 OAJ29901.1 - 1.7 8.2 5.5 2.9 7.4 3.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region BAF1_ABF1 PF04684.8 OAJ29901.1 - 2.4 6.9 13.0 3.1 6.5 1.5 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor CENP-B_dimeris PF09026.5 OAJ29901.1 - 8.9 6.6 12.2 20 5.5 8.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TPR_11 PF13414.1 OAJ29902.1 - 2.7e-26 90.9 15.6 2.4e-11 43.1 0.1 6.7 5 1 2 7 7 7 5 TPR repeat TPR_2 PF07719.12 OAJ29902.1 - 3.9e-16 57.5 26.0 0.011 15.6 0.0 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ29902.1 - 7e-15 53.9 12.6 1.8e-05 24.1 0.0 7.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ29902.1 - 1.6e-13 50.8 10.3 6.3e-06 26.7 0.4 8.4 6 1 4 10 10 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ29902.1 - 2.8e-10 40.3 12.1 4.3e-06 26.9 0.4 6.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ29902.1 - 3.6e-10 39.2 0.3 0.66 10.3 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ29902.1 - 7.2e-10 38.6 40.6 0.024 15.2 0.1 10.3 7 1 4 11 11 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ29902.1 - 5.1e-07 29.0 0.1 0.97 9.3 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ29902.1 - 1.7e-06 27.8 4.6 0.0003 20.6 0.7 6.4 4 1 5 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 OAJ29902.1 - 0.0027 17.8 11.9 1.1 9.4 0.0 5.1 4 1 3 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 OAJ29902.1 - 0.0072 16.1 0.8 0.0072 16.1 0.5 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ29902.1 - 0.12 12.2 18.6 0.33 10.8 0.1 6.7 8 1 1 9 9 8 0 Tetratricopeptide repeat Nop14 PF04147.7 OAJ29902.1 - 8.8 4.1 36.6 13 3.5 25.4 1.1 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_35 PF01301.14 OAJ29903.1 - 5.6e-70 236.1 0.0 8.7e-70 235.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 OAJ29903.1 - 1.5e-34 118.6 0.1 1.1e-18 67.5 0.0 2.5 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 OAJ29903.1 - 4.9e-27 94.4 0.0 7.9e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 OAJ29903.1 - 2.1e-07 30.2 0.0 5.4e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 OAJ29903.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) PPR_2 PF13041.1 OAJ29904.1 - 0.00051 19.9 0.0 0.047 13.6 0.0 2.7 3 0 0 3 3 3 1 PPR repeat family PPR_3 PF13812.1 OAJ29904.1 - 0.0013 18.8 1.4 2.9 8.3 0.0 5.1 5 0 0 5 5 5 1 Pentatricopeptide repeat domain DUF3464 PF11947.3 OAJ29904.1 - 0.058 12.8 0.6 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) TMEM171 PF15471.1 OAJ29904.1 - 1.4 7.6 5.8 8.6 5.0 0.1 3.0 3 0 0 3 3 3 0 Transmembrane protein family 171 Nop PF01798.13 OAJ29905.1 - 3.1e-58 195.3 0.2 6.4e-58 194.3 0.1 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 OAJ29905.1 - 1.6e-25 88.6 1.0 2.3e-25 88.1 0.1 1.8 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 OAJ29905.1 - 5e-18 65.0 0.0 5e-18 65.0 0.0 3.0 3 1 0 3 3 3 1 NOP5NT (NUC127) domain Sporozoite_P67 PF05642.6 OAJ29905.1 - 0.02 12.7 12.1 0.029 12.2 8.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BCDHK_Adom3 PF10436.4 OAJ29905.1 - 0.024 14.1 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase CDC45 PF02724.9 OAJ29905.1 - 1.3 6.9 26.2 2 6.3 18.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.4 OAJ29905.1 - 3.5 6.3 26.2 5.7 5.6 18.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DDHD PF02862.12 OAJ29905.1 - 8.5 6.1 13.0 21 4.7 9.0 1.8 1 0 0 1 1 1 0 DDHD domain ZZ PF00569.12 OAJ29906.1 - 6.2e-22 76.8 64.6 1.1e-07 31.2 1.7 6.1 5 1 0 5 5 5 4 Zinc finger, ZZ type PIG-U PF06728.8 OAJ29907.1 - 4.2e-77 259.5 10.2 5.1e-77 259.2 7.1 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.8 OAJ29907.1 - 5.8e-05 22.8 0.6 0.00041 20.0 0.4 2.1 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) DEAD PF00270.24 OAJ29908.1 - 7.9e-30 103.5 0.0 6.4e-29 100.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ29908.1 - 5.9e-18 64.5 0.1 1.6e-16 59.9 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain NADH_B2 PF14813.1 OAJ29909.1 - 0.0078 15.8 0.3 0.0095 15.5 0.2 1.3 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 NADHdh_A3 PF14987.1 OAJ29910.1 - 0.05 13.5 0.0 0.063 13.1 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 VWA_2 PF13519.1 OAJ29911.1 - 5.5e-12 46.1 0.0 2.8e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 OAJ29911.1 - 0.0068 16.1 0.0 0.022 14.4 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_S16 PF00886.14 OAJ29912.1 - 2.3e-24 84.8 4.3 7.5e-24 83.2 3.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S16 RRM_6 PF14259.1 OAJ29913.1 - 1.5e-33 114.5 0.0 2e-11 43.7 0.0 4.8 5 0 0 5 5 5 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ29913.1 - 2.4e-32 110.3 0.0 1.6e-12 46.8 0.0 4.0 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ29913.1 - 1.5e-14 53.5 0.0 1.4e-06 28.0 0.0 3.7 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAJ29913.1 - 5.9e-07 29.1 0.0 0.011 15.4 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 OAJ29913.1 - 0.00081 19.1 0.0 0.011 15.4 0.0 2.6 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 OAJ29913.1 - 0.051 13.5 0.0 0.51 10.3 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain DUF4651 PF15513.1 OAJ29913.1 - 0.074 12.5 0.1 27 4.2 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4651) ATP_bind_1 PF03029.12 OAJ29914.1 - 3.5e-72 242.7 0.0 1.2e-67 227.9 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 OAJ29914.1 - 0.00047 20.0 0.0 0.0024 17.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 OAJ29914.1 - 0.00053 20.1 0.1 0.0016 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 OAJ29914.1 - 0.0012 18.3 0.5 0.0092 15.4 0.2 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_10 PF12846.2 OAJ29914.1 - 0.0012 18.3 0.1 0.15 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 OAJ29914.1 - 0.0013 18.5 0.2 0.0039 17.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ29914.1 - 0.0014 19.4 0.1 0.0014 19.4 0.1 2.5 2 1 0 2 2 1 1 AAA domain CbiA PF01656.18 OAJ29914.1 - 0.0044 16.4 0.7 0.15 11.4 0.5 2.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 OAJ29914.1 - 0.01 15.4 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 OAJ29914.1 - 0.011 15.1 0.2 0.053 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 OAJ29914.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 OAJ29914.1 - 0.022 13.6 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ArgK PF03308.11 OAJ29914.1 - 0.031 13.0 0.1 1.8 7.2 0.0 2.3 2 0 0 2 2 2 0 ArgK protein AAA_29 PF13555.1 OAJ29914.1 - 0.034 13.6 0.1 0.07 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 OAJ29914.1 - 0.048 13.2 0.1 0.35 10.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAJ29914.1 - 0.072 13.4 0.1 0.072 13.4 0.1 2.5 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 OAJ29914.1 - 0.14 12.6 0.2 6.3 7.3 0.1 2.4 2 0 0 2 2 2 0 Miro-like protein cobW PF02492.14 OAJ29914.1 - 0.14 11.5 0.1 18 4.7 0.0 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 OAJ29914.1 - 0.24 10.9 0.1 0.48 9.9 0.1 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.12 OAJ29914.1 - 2.6 7.7 5.8 0.46 10.2 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF87 Thymidylate_kin PF02223.12 OAJ29914.1 - 3.7 6.8 5.1 10 5.4 0.0 2.6 3 0 0 3 3 3 0 Thymidylate kinase Thiolase_N PF00108.18 OAJ29915.1 - 4.5e-71 238.9 0.0 6.4e-71 238.4 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAJ29915.1 - 2.7e-41 139.8 0.6 8.6e-41 138.2 0.3 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 OAJ29915.1 - 0.00031 20.3 0.1 0.0099 15.5 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 OAJ29915.1 - 0.0066 16.4 0.2 0.021 14.8 0.1 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 OAJ29915.1 - 0.0096 15.4 2.7 0.042 13.3 0.5 2.8 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain DUF4504 PF14953.1 OAJ29916.1 - 9.9e-08 31.5 0.0 7.6e-07 28.6 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4504) LTD PF00932.14 OAJ29916.1 - 0.063 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Lamin Tail Domain FAD_binding_4 PF01565.18 OAJ29917.1 - 4.2e-22 78.1 1.5 7e-22 77.3 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAJ29917.1 - 0.0041 17.0 0.3 0.0089 15.9 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like PIN_4 PF13638.1 OAJ29918.1 - 2.3e-09 37.4 0.0 3.2e-09 37.0 0.0 1.4 1 1 0 1 1 1 1 PIN domain TcdB_toxin_midC PF12255.3 OAJ29918.1 - 0.056 13.0 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/C-terminal region Mit_KHE1 PF10173.4 OAJ29919.1 - 8.4e-52 175.7 0.8 1.2e-51 175.2 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Histone PF00125.19 OAJ29920.1 - 5.6e-19 68.0 0.1 8.1e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Exo_endo_phos PF03372.18 OAJ29921.1 - 4.2e-13 49.7 4.9 6.6e-13 49.1 3.4 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.11 OAJ29922.1 - 4e-35 121.1 40.5 7.5e-35 120.2 26.9 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ29922.1 - 2.3e-13 49.5 20.7 3.1e-12 45.8 6.8 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 OAJ29922.1 - 8.6e-07 27.5 13.1 4.7e-05 21.7 5.6 2.8 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 OAJ29922.1 - 2.9e-05 22.6 20.6 0.0026 16.2 5.4 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Shisa PF13908.1 OAJ29923.1 - 0.11 12.6 0.0 0.11 12.6 0.0 2.8 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Sporozoite_P67 PF05642.6 OAJ29924.1 - 0.45 8.3 3.0 0.65 7.7 2.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cpn60_TCP1 PF00118.19 OAJ29925.1 - 1.5e-149 498.7 1.9 1.7e-149 498.5 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AMP-binding PF00501.23 OAJ29926.1 - 4.8e-50 170.1 0.0 8.6e-50 169.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.19 OAJ29926.1 - 7.5e-12 44.1 0.7 0.00011 21.4 0.0 6.6 7 0 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.20 OAJ29926.1 - 3e-11 43.4 0.5 6.2e-11 42.3 0.3 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 OAJ29926.1 - 5e-09 36.9 2.3 7.3e-06 26.8 0.1 3.3 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.1 OAJ29926.1 - 0.0049 16.3 7.1 3.4 7.3 0.2 5.2 5 1 1 6 6 6 2 Hexapeptide repeat of succinyl-transferase GH3 PF03321.8 OAJ29926.1 - 0.48 8.8 0.1 14 4.0 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter DnaJ PF00226.26 OAJ29927.1 - 3.3e-24 84.3 0.4 5.6e-24 83.6 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 OAJ29927.1 - 4.9e-14 52.4 0.0 9.4e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Ashwin PF15323.1 OAJ29927.1 - 0.034 14.1 2.7 0.048 13.6 1.9 1.2 1 0 0 1 1 1 0 Developmental protein SR-25 PF10500.4 OAJ29927.1 - 0.059 12.8 6.0 0.093 12.1 4.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF605 PF04652.11 OAJ29928.1 - 1.2 8.4 9.3 1.6 8.0 6.5 1.1 1 0 0 1 1 1 0 Vta1 like DNA_pol_viral_N PF00242.12 OAJ29928.1 - 2.7 6.9 5.0 3.7 6.4 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain ABC_tran PF00005.22 OAJ29929.1 - 1.6e-15 57.6 0.1 2e-13 50.8 0.0 3.3 2 2 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 OAJ29929.1 - 6.5e-08 32.8 2.5 0.0048 16.9 0.2 3.1 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 OAJ29929.1 - 9.8e-07 28.6 0.0 0.013 15.3 0.0 2.8 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 OAJ29929.1 - 0.00037 20.8 0.2 0.00067 20.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 OAJ29929.1 - 0.0021 17.5 0.1 0.004 16.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 OAJ29929.1 - 0.016 14.5 0.1 0.17 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 OAJ29929.1 - 0.023 13.9 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit SMC_N PF02463.14 OAJ29929.1 - 0.025 13.7 0.1 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Guanylate_kin PF00625.16 OAJ29929.1 - 0.037 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA_19 PF13245.1 OAJ29929.1 - 0.041 13.6 0.1 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 OAJ29929.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 OAJ29929.1 - 0.14 11.0 0.1 0.37 9.6 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF258 PF03193.11 OAJ29929.1 - 0.17 11.0 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_15 PF13175.1 OAJ29929.1 - 0.17 10.8 0.0 0.38 9.7 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AMPKBI PF04739.10 OAJ29930.1 - 9.1e-27 92.8 0.0 1.6e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain Myb_DNA-bind_6 PF13921.1 OAJ29933.1 - 0.021 14.9 0.3 0.083 13.0 0.2 2.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF3712 PF12505.3 OAJ29934.1 - 1.7e-109 360.8 46.2 6.5e-23 81.1 0.0 10.3 10 0 0 10 10 10 7 Protein of unknown function (DUF3712) LEA_2 PF03168.8 OAJ29934.1 - 1.9e-06 28.1 19.1 0.21 11.9 0.0 8.9 8 0 0 8 8 8 2 Late embryogenesis abundant protein Bactofilin PF04519.8 OAJ29934.1 - 0.076 13.0 0.1 0.44 10.5 0.0 2.4 2 0 0 2 2 2 0 Polymer-forming cytoskeletal Apt1 PF10351.4 OAJ29934.1 - 5 5.8 6.2 7.8 5.2 4.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Cyclin_N PF00134.18 OAJ29935.1 - 3.8e-09 36.1 0.0 7.1e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 OAJ29935.1 - 4e-07 30.5 1.1 9.3e-07 29.3 0.0 2.2 2 2 0 2 2 2 1 Cyclin Ribosomal_60s PF00428.14 OAJ29935.1 - 2.4 8.6 12.5 7.5 7.0 8.7 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein TPR_11 PF13414.1 OAJ29936.1 - 1.5e-24 85.4 16.0 4.8e-12 45.3 0.1 3.5 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 OAJ29936.1 - 3.6e-22 76.9 0.5 5e-08 32.2 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ29936.1 - 1.9e-21 74.2 7.3 3.8e-06 26.4 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ29936.1 - 8.8e-15 53.8 6.8 0.00041 20.7 0.1 5.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ29936.1 - 1.9e-12 47.4 6.5 5.6e-08 33.2 0.2 4.8 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ29936.1 - 8e-12 44.3 2.5 0.00013 21.9 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ29936.1 - 1.3e-11 43.3 0.0 0.039 13.7 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ29936.1 - 1.5e-10 41.2 2.7 0.0048 17.2 0.2 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ29936.1 - 1.4e-09 37.7 10.6 1.8e-05 24.5 1.2 4.1 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ29936.1 - 5.8e-08 31.9 1.9 0.017 14.9 0.0 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ29936.1 - 5.5e-05 23.3 8.3 5.6 7.6 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ29936.1 - 0.00043 20.3 5.5 0.26 11.4 0.1 3.8 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ29936.1 - 0.0013 18.6 6.7 0.89 9.5 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ29936.1 - 0.0024 17.9 3.9 0.0045 17.0 0.4 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 OAJ29936.1 - 0.0098 14.9 3.3 1.2 8.1 0.7 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.12 OAJ29936.1 - 0.057 13.7 12.9 0.61 10.3 1.3 4.0 3 1 1 4 4 4 0 Bacterial transcriptional activator domain TPR_3 PF07720.7 OAJ29936.1 - 0.072 12.9 0.5 2.4 8.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ29936.1 - 0.34 10.7 8.3 0.33 10.8 0.7 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4407 PF14362.1 OAJ29936.1 - 6.7 5.5 13.8 0.31 9.9 0.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) ATG13 PF10033.4 OAJ29937.1 - 1.2e-26 93.5 0.0 2e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 Nuc_sug_transp PF04142.10 OAJ29938.1 - 6.1e-52 176.1 0.7 1.3e-36 125.9 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 OAJ29938.1 - 6.4e-05 23.1 4.2 6.4e-05 23.1 2.9 2.7 2 2 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 OAJ29938.1 - 0.00063 19.7 6.2 0.00063 19.7 4.3 3.1 2 2 1 3 3 3 1 EamA-like transporter family DUF3439 PF11921.3 OAJ29938.1 - 0.0077 15.9 0.1 0.024 14.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) TPT PF03151.11 OAJ29938.1 - 0.14 11.7 12.8 0.016 14.8 2.9 3.1 3 1 0 4 4 4 0 Triose-phosphate Transporter family OSCP PF00213.13 OAJ29939.1 - 1.1e-38 132.8 0.6 1.3e-38 132.5 0.4 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit PALP PF00291.20 OAJ29940.1 - 8.1e-63 212.4 0.1 8.1e-63 212.4 0.1 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Telomere_Sde2_2 PF13297.1 OAJ29940.1 - 0.13 11.5 0.2 4.8 6.5 0.0 2.9 3 0 0 3 3 3 0 Telomere stability C-terminal zf-CCCH_2 PF14608.1 OAJ29941.1 - 0.065 13.2 33.0 1.9 8.5 0.5 5.4 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type GYF PF02213.11 OAJ29942.1 - 0.0041 16.6 0.0 0.0096 15.4 0.0 1.6 1 0 0 1 1 1 1 GYF domain DUF2457 PF10446.4 OAJ29943.1 - 0.68 8.5 8.1 0.98 8.0 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 OAJ29943.1 - 1.2 7.1 5.6 1.8 6.5 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein ABC_tran PF00005.22 OAJ29944.1 - 1.8e-42 144.9 0.0 6.5e-24 84.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 OAJ29944.1 - 9.1e-35 120.3 16.9 3.9e-19 69.1 2.2 3.4 4 0 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.14 OAJ29944.1 - 2.5e-09 36.7 0.0 7.5e-05 22.0 0.0 3.6 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 OAJ29944.1 - 5e-05 22.7 0.2 0.2 11.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 OAJ29944.1 - 5.5e-05 23.2 0.0 1.7 8.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 OAJ29944.1 - 9.6e-05 22.5 0.2 0.28 11.3 0.0 3.6 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 OAJ29944.1 - 0.00011 21.2 0.0 0.031 13.1 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 OAJ29944.1 - 0.0016 17.8 1.8 0.052 13.0 0.0 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ29944.1 - 0.0038 17.2 7.9 0.011 15.6 1.2 3.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 OAJ29944.1 - 0.004 16.6 0.0 0.27 10.6 0.0 2.5 2 1 0 2 2 2 1 AAA-like domain KaiC PF06745.8 OAJ29944.1 - 0.016 14.3 0.2 0.37 9.8 0.0 2.3 2 0 0 2 2 2 0 KaiC TrwB_AAD_bind PF10412.4 OAJ29944.1 - 0.11 11.1 0.5 10 4.6 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.1 OAJ29944.1 - 0.13 13.1 1.1 0.81 10.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 OAJ29944.1 - 0.24 10.6 0.1 5.7 6.1 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein cobW PF02492.14 OAJ29944.1 - 0.28 10.6 1.6 0.99 8.8 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 OAJ29944.1 - 0.44 10.8 2.0 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 OAJ29944.1 - 0.72 9.6 3.5 0.21 11.3 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function DUF87 CDC45 PF02724.9 OAJ29944.1 - 3.1 5.7 3.7 4.8 5.0 2.6 1.2 1 0 0 1 1 1 0 CDC45-like protein ParA PF10609.4 OAJ29945.1 - 4.3e-32 109.8 0.0 9.5e-32 108.7 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 OAJ29945.1 - 6.2e-08 32.2 0.8 0.0015 17.9 0.5 2.3 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 OAJ29945.1 - 0.00073 18.6 0.2 0.0013 17.7 0.1 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.1 OAJ29945.1 - 0.005 16.2 0.0 0.0084 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 OAJ29945.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SelB-wing_3 PF09107.6 OAJ29945.1 - 0.032 13.6 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Fer4_NifH PF00142.13 OAJ29945.1 - 0.059 12.5 0.0 4.6 6.3 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Nucleoplasmin PF03066.10 OAJ29945.1 - 0.085 12.3 0.2 0.085 12.3 0.1 1.8 2 0 0 2 2 2 0 Nucleoplasmin NB-ARC PF00931.17 OAJ29945.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain VirE PF05272.6 OAJ29945.1 - 0.19 11.1 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E DUF4611 PF15387.1 OAJ29945.1 - 1.6 8.9 5.8 6.8 6.9 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) MIP PF00230.15 OAJ29946.1 - 1.8e-45 155.2 6.1 2.5e-45 154.7 4.2 1.2 1 0 0 1 1 1 1 Major intrinsic protein Apc1 PF12859.2 OAJ29946.1 - 0.038 14.2 0.6 0.12 12.6 0.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 COX15-CtaA PF02628.10 OAJ29948.1 - 1.5e-78 263.6 9.5 2.3e-77 259.8 6.6 2.6 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein DUF2414 PF10309.4 OAJ29949.1 - 2.9e-06 26.8 0.0 4.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) BRO1 PF03097.13 OAJ29950.1 - 3e-103 345.4 0.0 4.8e-103 344.8 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 OAJ29950.1 - 4.3e-53 180.2 9.1 7.7e-53 179.3 6.3 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV NOT2_3_5 PF04153.13 OAJ29951.1 - 1.7e-36 125.0 2.6 3.1e-36 124.1 1.8 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Tektin PF03148.9 OAJ29951.1 - 0.061 11.8 0.1 0.099 11.1 0.1 1.3 1 0 0 1 1 1 0 Tektin family Robl_LC7 PF03259.12 OAJ29951.1 - 0.99 9.0 0.0 0.99 9.0 0.0 3.1 3 0 0 3 3 3 0 Roadblock/LC7 domain API5 PF05918.6 OAJ29951.1 - 1.9 6.8 8.4 3.3 6.0 5.8 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) TF_Zn_Ribbon PF08271.7 OAJ29952.1 - 0.1 11.9 1.2 0.25 10.6 0.8 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Peptidase_M50 PF02163.17 OAJ29953.1 - 2.6e-15 55.8 0.3 9.9e-15 54.0 0.2 1.9 2 0 0 2 2 2 1 Peptidase family M50 Glyco_hydro_88 PF07470.8 OAJ29955.1 - 6.1e-15 55.0 2.9 2.5e-14 53.0 0.1 2.3 3 0 0 3 3 3 2 Glycosyl Hydrolase Family 88 Glyco_hydro_88 PF07470.8 OAJ29956.1 - 6.9e-11 41.7 0.8 5.9e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 SnoaL_4 PF13577.1 OAJ29956.1 - 0.14 12.0 1.2 0.3 10.9 0.4 1.9 2 0 0 2 2 2 0 SnoaL-like domain CAP PF00188.21 OAJ29957.1 - 5.1e-21 75.4 1.9 1e-20 74.4 1.3 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ABC_membrane PF00664.18 OAJ29958.1 - 1.7e-43 149.0 34.5 3.2e-28 98.9 11.4 3.6 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ29958.1 - 1.4e-40 138.7 0.0 5.8e-26 91.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAJ29958.1 - 4.1e-09 35.9 1.0 0.004 16.3 0.0 4.5 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAJ29958.1 - 4.7e-05 23.8 0.0 0.19 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAJ29958.1 - 0.00013 21.4 0.4 0.17 11.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 OAJ29958.1 - 0.00021 20.7 0.6 0.89 8.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 OAJ29958.1 - 0.003 17.0 0.4 2.3 7.5 0.1 2.7 2 1 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 OAJ29958.1 - 0.012 15.7 2.0 3.6 7.7 0.0 3.6 4 0 0 4 4 4 0 AAA domain DUF87 PF01935.12 OAJ29958.1 - 0.013 15.3 1.6 0.014 15.2 0.1 1.8 2 0 0 2 2 1 0 Domain of unknown function DUF87 AAA_21 PF13304.1 OAJ29958.1 - 0.037 13.9 1.4 2.2 8.1 0.0 3.2 3 1 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 OAJ29958.1 - 0.048 13.1 0.2 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 OAJ29958.1 - 0.12 12.5 0.2 4.2 7.5 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 OAJ29958.1 - 0.13 13.0 0.0 0.48 11.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 OAJ29958.1 - 0.15 11.2 0.2 12 5.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 OAJ29958.1 - 0.19 12.2 1.2 3.1 8.2 0.2 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 OAJ29958.1 - 0.69 9.8 5.9 0.24 11.3 0.2 2.8 2 2 0 2 2 2 0 AAA ATPase domain RNA_pol_3_Rpc31 PF11705.3 OAJ29960.1 - 0.89 9.4 12.2 1.6 8.6 8.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.9 OAJ29960.1 - 1.2 8.6 7.4 2.4 7.6 5.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HEAT_2 PF13646.1 OAJ29961.1 - 1.5e-24 86.0 3.8 1.2e-13 51.1 0.3 4.4 2 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 OAJ29961.1 - 2.3e-11 42.7 2.0 0.2 11.8 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat HEAT_PBS PF03130.11 OAJ29961.1 - 7.5e-11 41.4 8.4 0.0096 16.3 0.0 7.4 8 0 0 8 8 8 3 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 OAJ29961.1 - 1.4e-05 25.4 3.5 0.026 14.9 0.1 5.9 5 2 2 7 7 7 3 HEAT-like repeat Arm PF00514.18 OAJ29961.1 - 0.0058 16.4 0.0 1.2 9.0 0.0 2.9 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat PHD PF00628.24 OAJ29962.1 - 3.3e-13 49.0 20.1 1.6e-08 34.0 6.3 2.9 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.1 OAJ29962.1 - 4.2 6.6 5.7 0.91 8.7 1.4 1.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Glyco_transf_28 PF03033.15 OAJ29963.1 - 9.8e-25 86.9 0.0 2.2e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 OAJ29963.1 - 1.7e-05 24.2 0.0 0.37 10.3 0.0 2.9 3 0 0 3 3 3 2 GRAM domain UDPGT PF00201.13 OAJ29963.1 - 0.0027 16.3 0.0 0.0045 15.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.24 OAJ29963.1 - 0.0043 17.2 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 PH domain CTDII PF01556.13 OAJ29964.1 - 5.2e-22 77.5 0.2 5.2e-19 67.9 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 OAJ29964.1 - 1.2e-20 72.9 4.9 1.9e-20 72.3 3.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 OAJ29964.1 - 2.3e-16 59.5 16.9 3.9e-16 58.8 11.7 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 OAJ29964.1 - 0.02 14.5 7.8 1.3 8.7 2.0 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family TMEM95 PF15203.1 OAJ29964.1 - 0.22 10.8 6.0 0.59 9.5 2.8 2.1 1 1 1 2 2 2 0 TMEM95 family Cytochrom_c3_2 PF14537.1 OAJ29964.1 - 0.76 10.1 11.7 3.6 7.9 7.8 2.2 1 1 1 2 2 2 0 Cytochrome c3 DZR PF12773.2 OAJ29964.1 - 1.7 8.5 10.4 11 5.9 7.7 1.9 1 1 1 2 2 2 0 Double zinc ribbon Ras PF00071.17 OAJ29965.1 - 1.4e-47 161.0 0.0 1.6e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ29965.1 - 3.4e-17 63.0 0.1 6.2e-17 62.1 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 OAJ29965.1 - 1.9e-06 27.2 0.0 2.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ29965.1 - 2.2e-05 24.0 0.0 4.8e-05 22.8 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ29965.1 - 0.01 15.7 0.1 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.1 OAJ29965.1 - 0.025 13.9 0.0 0.032 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.11 OAJ29965.1 - 0.049 12.7 0.1 0.075 12.1 0.1 1.4 1 0 0 1 1 1 0 AIG1 family Usp PF00582.21 OAJ29966.1 - 3.9e-13 49.7 1.5 3.9e-13 49.7 1.1 2.2 2 1 0 2 2 2 1 Universal stress protein family DNA_pol_viral_N PF00242.12 OAJ29966.1 - 2.1 7.2 11.9 1.1 8.2 6.4 1.8 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 OAJ29966.1 - 6.4 4.9 16.8 12 4.0 11.6 1.4 1 0 0 1 1 1 0 Transmembrane protein Spc97_Spc98 PF04130.8 OAJ29967.1 - 2e-112 376.2 0.0 2.6e-112 375.9 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Acyl_transf_3 PF01757.17 OAJ29968.1 - 2e-05 23.6 35.2 2.8e-05 23.1 24.4 1.2 1 0 0 1 1 1 1 Acyltransferase family PAS_9 PF13426.1 OAJ29970.1 - 2.7e-21 75.9 0.0 1.9e-12 47.4 0.0 3.0 3 0 0 3 3 3 2 PAS domain PAS PF00989.19 OAJ29970.1 - 5.8e-13 48.6 0.6 4.6e-08 32.8 0.0 3.9 4 1 0 4 4 4 2 PAS fold PAS_3 PF08447.6 OAJ29970.1 - 1.2e-11 44.4 0.0 4.7e-06 26.5 0.0 4.3 4 0 0 4 4 4 2 PAS fold PAS_4 PF08448.5 OAJ29970.1 - 1.1e-06 28.6 0.0 0.00025 21.0 0.0 3.7 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.1 OAJ29970.1 - 7.8e-05 22.3 0.0 0.025 14.4 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.1 OAJ29970.1 - 0.005 16.7 0.6 0.04 13.8 0.0 2.7 3 0 0 3 3 3 1 PAS domain He_PIG PF05345.7 OAJ29971.1 - 0.14 12.2 0.0 2.9 7.9 0.0 2.1 1 1 1 2 2 2 0 Putative Ig domain Ammonium_transp PF00909.16 OAJ29972.1 - 1.6e-24 86.1 0.5 2.1e-15 56.1 0.0 2.3 1 1 1 2 2 2 2 Ammonium Transporter Family Malate_synthase PF01274.17 OAJ29972.1 - 1.3e-11 43.1 0.1 1.8e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Malate synthase RNA_pol_I_A49 PF06870.7 OAJ29972.1 - 2.1e-06 26.5 0.2 2.9e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor YqzM PF14141.1 OAJ29972.1 - 0.0066 16.2 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 YqzM-like protein GST_N_3 PF13417.1 OAJ29973.1 - 2.5e-09 37.2 0.0 4.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAJ29973.1 - 7.4e-07 28.9 3.0 1.1e-06 28.3 2.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ29973.1 - 3.4e-06 27.4 0.0 6.3e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAJ29973.1 - 7.9e-06 25.7 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ29973.1 - 0.0062 16.4 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LETM1 PF07766.8 OAJ29974.1 - 2.7e-17 62.6 0.1 1.1e-08 34.4 0.0 2.4 2 1 0 2 2 2 2 LETM1-like protein RAP1 PF07218.6 OAJ29974.1 - 2.1 6.3 6.6 4.1 5.3 4.6 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Acyl_transf_1 PF00698.16 OAJ29975.1 - 7.6e-60 202.8 0.1 5.3e-58 196.8 0.0 3.3 4 0 0 4 4 4 1 Acyl transferase domain DUF1729 PF08354.5 OAJ29975.1 - 6.9e-31 105.8 0.4 1.7e-30 104.5 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 OAJ29975.1 - 4.2e-28 97.2 0.0 1.3e-27 95.6 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 OAJ29975.1 - 1.2e-09 38.0 0.0 3.9e-08 33.1 0.0 2.6 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Pkinase PF00069.20 OAJ29977.1 - 7.2e-60 202.3 0.0 5.1e-58 196.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ29977.1 - 9.4e-27 93.7 0.0 1e-25 90.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ29977.1 - 1.4e-05 24.2 0.0 2.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like MmgE_PrpD PF03972.9 OAJ29979.1 - 2.4e-08 32.6 0.1 2.5e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family HSP70 PF00012.15 OAJ29980.1 - 8.6e-54 182.4 0.0 1.1e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Methyltransf_8 PF05148.10 OAJ29980.1 - 0.00042 20.0 0.0 0.00081 19.0 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Tox-ART-HYE1 PF15634.1 OAJ29980.1 - 0.084 11.8 0.2 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase MmgE_PrpD PF03972.9 OAJ29981.1 - 2.7e-91 305.9 0.3 3.2e-91 305.7 0.2 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Methyltransf_31 PF13847.1 OAJ29982.1 - 4.7e-12 45.7 0.3 7.9e-12 45.0 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 OAJ29982.1 - 2.1e-10 40.2 0.1 3.7e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 OAJ29982.1 - 2.3e-10 41.0 0.4 5.7e-10 39.7 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ29982.1 - 7.2e-09 35.5 0.0 2e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ29982.1 - 6.8e-08 32.5 0.0 1.8e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ29982.1 - 1.4e-07 31.9 0.0 3.2e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAJ29982.1 - 4.2e-07 29.3 0.0 5.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 OAJ29982.1 - 5.5e-06 25.8 0.1 1.2e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.11 OAJ29982.1 - 1e-05 24.7 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.6 OAJ29982.1 - 1.1e-05 24.3 0.0 1.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 OAJ29982.1 - 2.6e-05 24.5 0.0 5.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ29982.1 - 0.00011 22.5 0.1 0.00026 21.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 OAJ29982.1 - 0.0014 18.6 0.2 0.0022 18.0 0.2 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 OAJ29982.1 - 0.0034 16.9 0.0 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 OAJ29982.1 - 0.0041 16.5 0.1 0.0066 15.9 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 OAJ29982.1 - 0.0072 15.9 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 OAJ29982.1 - 0.021 13.9 0.3 0.052 12.6 0.1 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MetW PF07021.7 OAJ29982.1 - 0.041 13.2 0.1 0.07 12.4 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 OAJ29982.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 OAJ29982.1 - 0.07 12.2 1.8 0.16 11.1 0.4 2.2 2 1 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_4 PF02390.12 OAJ29982.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Ferric_reduct PF01794.14 OAJ29983.1 - 2.5e-16 59.8 8.9 2.5e-16 59.8 6.2 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 OAJ29983.1 - 1.2e-11 44.7 0.0 2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 OAJ29983.1 - 3.7e-08 33.1 0.0 9e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain DUF92 PF01940.11 OAJ29984.1 - 2.8e-54 183.6 5.0 1.5e-52 178.0 3.5 2.2 1 1 0 1 1 1 1 Integral membrane protein DUF92 Sulfate_transp PF00916.15 OAJ29985.1 - 2.9e-78 262.7 8.1 5e-78 261.9 5.6 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 OAJ29985.1 - 1.6e-30 104.6 4.0 1.6e-30 104.6 2.8 3.7 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 OAJ29985.1 - 3.8e-10 39.1 0.0 7.3e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain Mucin PF01456.12 OAJ29987.1 - 7.9e-05 22.4 17.3 0.00015 21.5 10.7 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein Peptidase_S24 PF00717.18 OAJ29987.1 - 0.14 11.8 0.1 0.63 9.7 0.0 2.1 3 0 0 3 3 3 0 Peptidase S24-like Hexapep PF00132.19 OAJ29988.1 - 0.00025 20.4 0.8 0.3 10.6 0.2 2.8 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 OAJ29988.1 - 0.14 11.7 3.5 8.8 5.9 0.1 3.4 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 OAJ29988.1 - 0.16 11.2 0.0 0.68 9.1 0.0 1.9 2 0 0 2 2 2 0 Nucleotidyl transferase hDGE_amylase PF14701.1 OAJ29989.1 - 5.2e-158 526.3 0.0 7.4e-158 525.8 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 OAJ29989.1 - 1.7e-106 356.0 0.0 2.4e-106 355.5 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 OAJ29989.1 - 7.8e-81 271.0 0.0 1.2e-80 270.4 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 OAJ29989.1 - 1.3e-18 66.5 0.0 2.6e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 OAJ29989.1 - 0.0043 16.4 0.0 0.28 10.5 0.0 2.3 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Mucin PF01456.12 OAJ29989.1 - 7.2 6.3 16.6 15 5.3 11.5 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Maf1 PF09174.5 OAJ29990.1 - 2.8e-27 95.7 0.0 2e-16 60.3 0.0 3.6 3 0 0 3 3 3 3 Maf1 regulator Sad1_UNC PF07738.8 OAJ29991.1 - 1.2e-12 47.7 0.0 5.7e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal RVT_1 PF00078.22 OAJ29994.1 - 1.9e-22 79.6 0.0 3e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ29994.1 - 2e-14 53.1 0.1 4.9e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ29994.1 - 1.9e-05 24.7 0.2 3.5e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC_3 PF13917.1 OAJ29995.1 - 5.1 6.9 17.8 2 8.2 2.0 2.5 2 0 0 2 2 2 0 Zinc knuckle Alg6_Alg8 PF03155.10 OAJ29996.1 - 2.3e-112 376.2 8.7 1.9e-79 267.6 4.4 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family PGM_PMM_I PF02878.11 OAJ29997.1 - 2.9e-22 78.6 0.1 2.9e-12 46.2 0.1 2.6 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 OAJ29997.1 - 2.4e-10 40.6 0.0 1.2e-09 38.4 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 OAJ29997.1 - 4.5e-09 36.1 0.1 1.2e-08 34.7 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 OAJ29997.1 - 0.00013 21.9 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III BCNT PF07572.7 OAJ29998.1 - 1.5e-13 50.4 4.4 8e-08 32.1 1.0 2.2 2 0 0 2 2 2 2 Bucentaur or craniofacial development APC_CDC26 PF10471.4 OAJ29998.1 - 2.3 9.0 6.6 0.34 11.6 1.9 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 NRDE PF05742.7 OAJ29999.1 - 2.1e-34 119.0 0.0 1.9e-31 109.4 0.0 3.2 1 1 0 1 1 1 1 NRDE protein Myc_N PF01056.13 OAJ30001.1 - 0.00062 19.0 3.5 0.00062 19.0 2.4 1.8 1 1 1 2 2 2 1 Myc amino-terminal region BRE1 PF08647.6 OAJ30001.1 - 0.022 14.7 4.1 0.95 9.4 0.3 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase HALZ PF02183.13 OAJ30001.1 - 0.053 13.2 0.5 0.093 12.4 0.3 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Abhydrolase_1 PF00561.15 OAJ30002.1 - 1.4e-26 93.5 0.4 3.4e-12 46.4 0.0 3.2 3 0 0 3 3 3 3 alpha/beta hydrolase fold COX6A PF02046.10 OAJ30003.1 - 8.1e-24 83.7 0.5 1.4e-19 70.0 0.1 2.2 2 0 0 2 2 2 2 Cytochrome c oxidase subunit VIa Git3 PF11710.3 OAJ30005.1 - 5.8e-10 39.0 8.8 1.4e-09 37.8 6.1 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 OAJ30005.1 - 1.1e-08 34.5 0.0 3.5e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 OAJ30005.1 - 0.00045 19.9 0.7 0.0021 17.8 0.0 2.3 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Flu_M2 PF00599.12 OAJ30005.1 - 0.49 10.2 1.4 2.1 8.1 0.0 2.7 3 0 0 3 3 3 0 Influenza Matrix protein (M2) FAR1 PF03101.10 OAJ30006.1 - 7.5e-06 26.3 0.0 1.3e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain HECT PF00632.20 OAJ30007.1 - 1.5e-78 264.1 0.0 2.1e-78 263.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Fungal_trans PF04082.13 OAJ30008.1 - 7.5e-12 44.6 0.4 1.1e-11 44.1 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DER1 PF04511.10 OAJ30009.1 - 2.4e-06 27.1 5.3 8.8e-06 25.3 3.7 1.7 1 1 0 1 1 1 1 Der1-like family DUF1751 PF08551.5 OAJ30009.1 - 2.3e-05 24.6 1.3 3.5e-05 24.0 0.4 1.7 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 OAJ30009.1 - 3.1e-05 24.0 3.2 7.1e-05 22.8 2.2 1.8 1 1 0 1 1 1 1 Rhomboid family Oxidored_q2 PF00420.19 OAJ30009.1 - 5.1 6.7 7.3 0.64 9.6 1.2 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L ELMO_CED12 PF04727.8 OAJ30010.1 - 1.2e-31 109.5 0.0 1.9e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 OAJ30010.1 - 3.4e-09 36.6 0.0 5.3e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) Drf_FH3 PF06367.11 OAJ30010.1 - 0.0014 18.0 0.1 0.0026 17.1 0.1 1.3 1 0 0 1 1 1 1 Diaphanous FH3 Domain V-ATPase_H_N PF03224.9 OAJ30010.1 - 0.0024 17.0 0.1 0.011 14.9 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H Herpes_V23 PF01802.12 OAJ30010.1 - 0.14 11.1 0.2 2.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus VP23 like capsid protein PHF5 PF03660.9 OAJ30011.1 - 2.9e-44 149.5 8.9 3.1e-44 149.4 6.1 1.0 1 0 0 1 1 1 1 PHF5-like protein UPF0547 PF10571.4 OAJ30011.1 - 0.052 13.2 2.1 0.052 13.2 1.5 3.3 5 0 0 5 5 5 0 Uncharacterised protein family UPF0547 DZR PF12773.2 OAJ30011.1 - 0.35 10.7 13.9 5 7.0 9.2 2.7 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.1 OAJ30011.1 - 0.45 10.2 11.4 2.8 7.7 0.2 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 OAJ30011.1 - 0.74 9.5 11.5 0.036 13.7 2.7 2.3 1 1 1 2 2 2 0 PHD-finger PolC_DP2 PF03833.8 OAJ30011.1 - 7.9 3.9 6.9 7.8 4.0 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Pkinase PF00069.20 OAJ30012.1 - 5.6e-60 202.6 0.0 4.6e-33 114.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ30012.1 - 9.5e-20 70.7 0.0 2.8e-16 59.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 OAJ30012.1 - 0.021 13.8 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ30012.1 - 0.062 13.0 4.1 0.13 11.9 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family PPP4R2 PF09184.6 OAJ30012.1 - 0.31 10.5 4.3 0.7 9.3 3.0 1.5 1 0 0 1 1 1 0 PPP4R2 STE3 PF02076.10 OAJ30015.1 - 5.7e-95 317.6 12.9 7.6e-95 317.2 9.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor Epiglycanin_C PF14654.1 OAJ30015.1 - 0.033 14.2 0.7 0.08 12.9 0.5 1.6 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region VWA_2 PF13519.1 OAJ30016.1 - 1.4e-12 48.0 0.1 1.8e-12 47.6 0.1 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 OAJ30016.1 - 3.6e-06 26.7 0.0 4.7e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 OAJ30016.1 - 4.2e-06 26.6 0.1 5e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain Chorismate_bind PF00425.13 OAJ30016.1 - 0.027 13.8 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 chorismate binding enzyme IATP PF04568.7 OAJ30017.1 - 2.2e-13 50.0 0.2 2.4e-13 49.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP YgaB PF14182.1 OAJ30017.1 - 0.1 12.8 2.8 0.13 12.4 1.9 1.1 1 0 0 1 1 1 0 YgaB-like protein PspB PF06667.7 OAJ30017.1 - 0.33 10.9 1.5 0.47 10.4 1.1 1.2 1 0 0 1 1 1 0 Phage shock protein B ATP_sub_h PF10775.4 OAJ30018.1 - 7.4e-23 80.0 1.0 1.1e-22 79.5 0.7 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 OAJ30018.1 - 0.0053 16.6 0.0 0.013 15.3 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase coupling factor 6 Got1 PF04178.7 OAJ30019.1 - 1.3e-22 80.1 13.8 1.8e-22 79.6 9.5 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Acyl_transf_3 PF01757.17 OAJ30019.1 - 0.087 11.6 19.0 0.12 11.2 13.2 1.1 1 0 0 1 1 1 0 Acyltransferase family adh_short PF00106.20 OAJ30021.1 - 0.07 13.0 1.8 0.23 11.3 0.3 2.4 2 1 0 2 2 2 0 short chain dehydrogenase RTA1 PF04479.8 OAJ30022.1 - 1.3e-32 113.1 1.6 3.9e-25 88.6 0.1 2.1 2 0 0 2 2 2 2 RTA1 like protein peroxidase PF00141.18 OAJ30023.1 - 2.2e-51 174.5 0.0 3e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Transposase_21 PF02992.9 OAJ30024.1 - 1.5e-17 63.4 0.1 2.5e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Sigma_reg_C PF13791.1 OAJ30024.1 - 0.078 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma factor regulator C-terminal Pyrophosphatase PF00719.14 OAJ30025.1 - 9.2e-54 181.1 0.2 1.2e-53 180.7 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase ChaC PF04752.7 OAJ30026.1 - 1.7e-50 171.4 0.0 4.1e-50 170.2 0.0 1.7 1 0 0 1 1 1 1 ChaC-like protein DnaJ PF00226.26 OAJ30026.1 - 1.2e-26 92.1 0.7 3.9e-26 90.5 0.5 2.0 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 OAJ30026.1 - 2.6e-09 36.9 1.0 5.9e-09 35.8 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAJ30026.1 - 5e-06 26.5 0.5 9.2e-06 25.6 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 OAJ30026.1 - 0.011 15.8 0.1 0.035 14.2 0.1 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) APOBEC_C PF05240.9 OAJ30026.1 - 0.084 12.2 0.3 0.18 11.2 0.2 1.5 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Lactamase_B_3 PF13483.1 OAJ30027.1 - 0.037 13.7 0.0 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Cut8_N PF14482.1 OAJ30028.1 - 0.078 12.9 1.8 2.9 7.9 0.2 2.9 2 1 0 2 2 2 0 Cut8 proteasome-binding domain DUF4218 PF13960.1 OAJ30029.1 - 0.00041 19.8 0.0 0.00077 18.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF2360 PF10152.4 OAJ30030.1 - 0.0085 16.3 0.2 0.048 13.9 0.1 2.2 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Sugarporin_N PF11471.3 OAJ30030.1 - 0.046 13.3 0.3 0.096 12.3 0.2 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Elongin_A PF06881.6 OAJ30031.1 - 0.097 13.0 2.1 11 6.4 0.9 3.0 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A NDT80_PhoG PF05224.7 OAJ30032.1 - 2.4e-09 37.4 0.0 1.6e-08 34.7 0.0 2.2 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Ank_2 PF12796.2 OAJ30033.1 - 8.9e-17 61.2 0.1 3.1e-16 59.4 0.1 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ30033.1 - 1.4e-14 54.1 0.1 2e-07 31.3 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ30033.1 - 4.3e-13 49.0 0.4 1.4e-08 34.6 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ30033.1 - 2.8e-12 45.6 0.0 7.3e-05 22.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 OAJ30033.1 - 9.4e-12 44.1 2.4 3.8e-06 26.4 0.0 4.6 4 1 0 4 4 4 2 Ankyrin repeat HSF_DNA-bind PF00447.12 OAJ30034.1 - 4.9e-35 119.8 0.1 8.9e-35 118.9 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 OAJ30034.1 - 3e-23 81.9 0.1 5.9e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Bromodomain PF00439.20 OAJ30035.1 - 2.6e-16 59.3 0.0 7e-16 57.9 0.0 1.6 2 0 0 2 2 2 1 Bromodomain CBM_6 PF03422.10 OAJ30035.1 - 0.0015 18.6 0.5 0.39 10.8 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) TFIIA PF03153.8 OAJ30035.1 - 0.0043 17.0 22.2 0.0043 17.0 15.4 3.1 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit SMC_N PF02463.14 OAJ30036.1 - 3.4e-68 229.1 28.7 3.4e-67 225.8 19.9 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 OAJ30036.1 - 3.6e-27 94.7 0.0 1.5e-26 92.7 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 OAJ30036.1 - 1.5e-13 51.5 3.7 1.5e-13 51.5 2.6 7.1 3 2 2 6 6 2 1 AAA domain AAA_21 PF13304.1 OAJ30036.1 - 6.1e-13 49.3 11.2 1.7e-06 28.2 0.2 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 OAJ30036.1 - 4e-05 23.0 0.0 8.4e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 OAJ30036.1 - 4.7e-05 20.9 29.9 4.7e-05 20.9 20.7 4.3 3 1 1 4 4 4 1 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 OAJ30036.1 - 8.8e-05 21.8 23.4 0.028 13.5 0.8 4.6 3 1 1 4 4 4 3 Reovirus sigma C capsid protein AAA_13 PF13166.1 OAJ30036.1 - 0.0019 16.7 14.9 0.0019 16.7 10.3 6.0 3 2 1 5 5 4 2 AAA domain TMF_DNA_bd PF12329.3 OAJ30036.1 - 0.0039 16.9 4.2 0.0039 16.9 2.9 11.1 9 2 3 12 12 11 2 TATA element modulatory factor 1 DNA binding SpoOE-like PF09388.5 OAJ30036.1 - 0.012 15.0 0.4 0.012 15.0 0.3 4.0 3 0 0 3 3 3 0 Spo0E like sporulation regulatory protein Img2 PF05046.9 OAJ30036.1 - 0.029 14.6 3.9 0.13 12.4 0.9 3.2 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Baculo_PEP_C PF04513.7 OAJ30036.1 - 0.098 12.4 15.4 0.17 11.7 0.4 4.9 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus SCAMP PF04144.8 OAJ30037.1 - 3.7e-44 150.7 1.8 4.4e-44 150.4 1.3 1.0 1 0 0 1 1 1 1 SCAMP family HAP1_N PF04849.8 OAJ30037.1 - 0.12 11.2 0.8 0.16 10.8 0.6 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region SAM_2 PF07647.12 OAJ30038.1 - 1.1e-09 37.9 0.0 2.1e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 OAJ30038.1 - 3.5e-06 27.0 0.0 7.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.1 OAJ30038.1 - 0.14 12.1 0.2 0.34 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Velvet PF11754.3 OAJ30039.1 - 2e-22 79.7 0.1 1.3e-21 77.1 0.1 1.8 1 1 0 1 1 1 1 Velvet factor XPA_C PF05181.7 OAJ30040.1 - 0.14 11.7 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 XPA protein C-terminus MarC PF01914.12 OAJ30040.1 - 0.38 9.8 0.6 0.83 8.7 0.4 1.5 1 0 0 1 1 1 0 MarC family integral membrane protein ISG65-75 PF11727.3 OAJ30040.1 - 0.46 9.4 12.2 0.76 8.7 8.4 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein NARP1 PF12569.3 OAJ30040.1 - 5.9 5.5 14.5 11 4.6 10.1 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2514 PF10721.4 OAJ30040.1 - 6.5 6.4 20.8 0.36 10.5 10.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Glyco_hydro_16 PF00722.16 OAJ30041.1 - 8e-07 28.5 0.1 1.8e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Velvet PF11754.3 OAJ30042.1 - 6.6e-34 117.3 0.0 1.5e-33 116.1 0.0 1.5 1 0 0 1 1 1 1 Velvet factor CtIP_N PF10482.4 OAJ30043.1 - 0.0014 18.3 3.3 0.0023 17.7 2.3 1.2 1 0 0 1 1 1 1 Tumour-suppressor protein CtIP N-terminal domain TMF_TATA_bd PF12325.3 OAJ30043.1 - 0.015 14.9 4.6 0.024 14.3 3.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 OAJ30043.1 - 0.038 12.9 4.3 0.059 12.3 3.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF904 PF06005.7 OAJ30043.1 - 0.42 10.9 6.2 0.74 10.1 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) HECT_2 PF09814.4 OAJ30044.1 - 1.3e-29 103.1 0.0 1.4e-29 102.9 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Nudix_N_2 PF14803.1 OAJ30044.1 - 0.34 10.6 2.0 0.59 9.8 0.1 2.4 3 0 0 3 3 3 0 Nudix N-terminal Peroxidase_2 PF01328.12 OAJ30046.1 - 2.2e-15 56.1 0.8 7.6e-15 54.3 0.5 1.8 1 1 0 1 1 1 1 Peroxidase, family 2 Solute_trans_a PF03619.11 OAJ30047.1 - 5.1e-77 258.8 21.9 6.4e-77 258.5 15.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha BTV_NS2 PF04514.7 OAJ30047.1 - 0.5 9.2 1.9 0.91 8.3 1.3 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Abhydrolase_3 PF07859.8 OAJ30048.1 - 3.9e-33 114.8 0.1 5.1e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ30048.1 - 6.2e-06 26.0 0.0 1.3e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ30048.1 - 5.6e-05 22.4 0.0 0.14 11.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 OAJ30048.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 OAJ30048.1 - 0.0034 17.3 1.7 0.0073 16.2 1.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 OAJ30048.1 - 0.0044 16.7 0.0 0.025 14.2 0.0 2.1 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.3 OAJ30048.1 - 0.0046 16.3 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DLH PF01738.13 OAJ30048.1 - 0.074 12.3 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Apc5 PF12862.2 OAJ30049.1 - 1.9e-14 53.2 1.6 5.1e-14 51.8 1.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 OAJ30049.1 - 0.12 12.2 8.9 1.6 8.6 0.9 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ30049.1 - 2.1 8.4 6.2 16 5.6 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat HNH_2 PF13391.1 OAJ30050.1 - 0.028 14.1 0.2 0.064 13.0 0.1 1.6 1 0 0 1 1 1 0 HNH endonuclease HMGL-like PF00682.14 OAJ30051.1 - 5.8e-41 140.7 1.4 1e-39 136.6 0.9 2.6 1 1 0 1 1 1 1 HMGL-like ApoO PF09769.4 OAJ30052.1 - 3.2e-32 111.4 1.0 5.1e-32 110.7 0.3 1.6 2 0 0 2 2 2 1 Apolipoprotein O DUF883 PF05957.8 OAJ30052.1 - 0.02 15.2 0.0 2.3 8.6 0.0 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 OAJ30052.1 - 0.087 12.3 0.8 4.7 6.6 0.2 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain PAP_assoc PF03828.14 OAJ30053.1 - 1e-16 60.6 0.2 1.9e-16 59.7 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 OAJ30053.1 - 1.6e-06 28.3 0.0 3.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Apc1 PF12859.2 OAJ30056.1 - 2.9e-12 46.7 0.0 1.4e-11 44.4 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 OAJ30056.1 - 8.9e-05 22.5 12.6 0.11 12.7 0.0 6.0 7 0 0 7 7 7 3 Proteasome/cyclosome repeat RNA_pol_L_2 PF13656.1 OAJ30057.1 - 4.8e-24 83.6 0.0 6e-24 83.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 OAJ30057.1 - 3.7e-11 41.9 0.0 4.9e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mito_carr PF00153.22 OAJ30058.1 - 3e-65 215.9 2.6 4.7e-23 80.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ku PF02735.11 OAJ30059.1 - 5.1e-17 61.9 0.3 8e-16 58.0 0.0 2.8 3 0 0 3 3 3 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 OAJ30059.1 - 3.9e-12 46.1 0.1 9.9e-12 44.8 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.10 OAJ30059.1 - 0.003 17.0 0.0 0.081 12.3 0.0 2.7 3 1 0 3 3 3 1 Ku70/Ku80 N-terminal alpha/beta domain Ehbp PF10622.4 OAJ30059.1 - 0.064 13.2 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 Energy-converting hydrogenase B subunit P (EhbP) Hexapep PF00132.19 OAJ30060.1 - 1.6e-07 30.4 15.8 0.019 14.4 0.9 4.0 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 OAJ30060.1 - 0.00015 21.2 11.6 0.019 14.5 2.4 3.3 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase MIF4G PF02854.14 OAJ30061.1 - 2.7e-15 56.3 0.0 6.9e-15 55.0 0.0 1.7 1 1 0 1 1 1 1 MIF4G domain MA3 PF02847.12 OAJ30061.1 - 6.8e-10 38.6 0.0 1.6e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 MA3 domain Nop14 PF04147.7 OAJ30061.1 - 0.00021 19.3 23.2 0.00035 18.6 16.1 1.2 1 0 0 1 1 1 1 Nop14-like family TFIIA PF03153.8 OAJ30061.1 - 0.0044 16.9 22.7 0.0044 16.9 15.7 1.7 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF1290 PF06947.7 OAJ30061.1 - 0.12 12.3 0.2 0.24 11.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) COPI_C PF06957.6 OAJ30061.1 - 0.63 8.5 7.7 1.4 7.3 5.3 1.5 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus COX5B PF01215.14 OAJ30062.1 - 8.7e-42 142.0 0.0 1.1e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.4 OAJ30062.1 - 0.0087 15.8 0.3 0.013 15.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger domain MSP1_C PF07462.6 OAJ30062.1 - 0.4 9.0 1.3 0.5 8.6 0.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Chorismate_synt PF01264.16 OAJ30063.1 - 6.1e-132 439.2 0.1 1e-131 438.5 0.0 1.3 1 1 0 1 1 1 1 Chorismate synthase DUF1295 PF06966.7 OAJ30065.1 - 4.6e-42 143.9 0.0 8.3e-42 143.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 OAJ30065.1 - 0.037 14.2 0.0 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1628 PF07790.6 OAJ30065.1 - 0.058 14.1 0.0 0.16 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) DUF4491 PF14898.1 OAJ30065.1 - 0.069 13.2 0.3 0.17 12.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) Steroid_dh PF02544.11 OAJ30065.1 - 0.083 12.6 0.0 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase TGS PF02824.16 OAJ30067.1 - 1.3e-21 76.1 0.0 2.5e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 OAJ30067.1 - 1.7e-18 66.6 0.1 3.6e-18 65.6 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ30067.1 - 9.1e-10 38.0 0.1 2.5e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 OAJ30067.1 - 0.00028 20.7 0.1 0.076 12.8 0.0 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 OAJ30067.1 - 0.0078 15.6 0.5 6.7 6.0 0.1 3.3 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Miro PF08477.8 OAJ30067.1 - 0.012 16.0 0.0 0.033 14.6 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein ArgK PF03308.11 OAJ30067.1 - 0.018 13.8 0.7 0.04 12.6 0.1 1.8 2 0 0 2 2 2 0 ArgK protein PLDc_2 PF13091.1 OAJ30068.1 - 1.6e-13 50.5 0.0 5.4e-08 32.6 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain ERG2_Sigma1R PF04622.7 OAJ30069.1 - 9.6e-83 276.6 0.0 1.4e-82 276.1 0.0 1.2 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein RNA_POL_M_15KD PF02150.11 OAJ30069.1 - 0.065 12.9 0.3 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit RRM_1 PF00076.17 OAJ30070.1 - 2.4e-31 107.1 0.0 3.9e-12 45.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ30070.1 - 5.8e-27 93.4 0.0 4.5e-10 39.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ30070.1 - 4.5e-18 64.8 0.0 2.1e-06 27.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macro PF01661.16 OAJ30071.1 - 1.3e-41 141.2 0.1 1.9e-41 140.6 0.1 1.2 1 0 0 1 1 1 1 Macro domain BcrAD_BadFG PF01869.15 OAJ30072.1 - 8.4e-07 28.5 0.1 0.0045 16.3 0.1 2.3 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Voldacs PF03517.8 OAJ30072.1 - 1.1 9.1 6.1 4.1 7.2 1.2 2.6 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling RXT2_N PF08595.6 OAJ30072.1 - 2 8.1 6.8 0.27 11.0 1.5 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal Aminotran_3 PF00202.16 OAJ30073.1 - 5.8e-105 350.8 0.0 9.6e-105 350.1 0.0 1.3 2 0 0 2 2 2 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 OAJ30073.1 - 0.0075 15.4 0.0 0.036 13.2 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase VPS9 PF02204.13 OAJ30075.1 - 4.5e-31 106.9 0.0 8.5e-31 106.0 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PUA PF01472.15 OAJ30076.1 - 3.1e-15 55.6 0.0 4.8e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 PUA domain MgtE PF01769.11 OAJ30077.1 - 2.7e-20 73.0 34.8 6.8e-09 36.1 0.3 5.3 6 0 0 6 6 6 4 Divalent cation transporter Ribosomal_L23eN PF03939.8 OAJ30078.1 - 8.7e-20 70.5 11.9 1.6e-19 69.6 8.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 OAJ30078.1 - 9.9e-12 44.6 0.1 2e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Cyt-b5 PF00173.23 OAJ30079.1 - 5.7e-09 35.6 0.0 8.1e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Arrestin_C PF02752.17 OAJ30080.1 - 4.6e-14 52.6 0.0 1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Ribosomal_L22 PF00237.14 OAJ30081.1 - 5.3e-31 106.6 0.1 7.2e-31 106.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF2235 PF09994.4 OAJ30083.1 - 2.3e-34 119.0 0.0 3.1e-33 115.3 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) zf-RING_2 PF13639.1 OAJ30084.1 - 0.042 13.6 3.5 0.07 12.9 2.4 1.3 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.2 OAJ30084.1 - 1.3 9.1 3.7 2.2 8.4 2.6 1.3 1 0 0 1 1 1 0 RING-H2 zinc finger DHBP_synthase PF00926.14 OAJ30085.1 - 1.9e-69 232.7 0.0 2.3e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase PEP-utilizers PF00391.18 OAJ30085.1 - 0.031 13.8 0.0 0.08 12.5 0.0 1.7 1 1 0 1 1 1 0 PEP-utilising enzyme, mobile domain Macoilin PF09726.4 OAJ30086.1 - 1.7 6.7 5.1 1.8 6.7 3.5 1.0 1 0 0 1 1 1 0 Transmembrane protein DLIC PF05783.6 OAJ30086.1 - 3.8 6.0 6.3 5 5.6 4.4 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF2413 PF10310.4 OAJ30086.1 - 4 6.1 6.4 5.2 5.7 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) zf-Tim10_DDP PF02953.10 OAJ30087.1 - 0.024 13.9 2.8 0.55 9.5 0.1 2.3 2 0 0 2 2 2 0 Tim10/DDP family zinc finger Toxin_25 PF08095.6 OAJ30087.1 - 0.77 9.5 7.8 1.7 8.4 0.3 2.7 2 1 0 2 2 2 0 Hefutoxin family Peptidase_S8 PF00082.17 OAJ30088.1 - 1.3e-46 159.0 0.0 3.4e-46 157.6 0.0 1.7 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 OAJ30088.1 - 1.4e-11 44.7 0.1 2.9e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 OAJ30088.1 - 1e-09 37.9 1.1 3.6e-09 36.2 0.0 2.3 2 0 0 2 2 2 1 PA domain Inhibitor_I9 PF05922.11 OAJ30088.1 - 0.16 12.5 0.0 0.78 10.3 0.0 2.1 2 0 0 2 2 2 0 Peptidase inhibitor I9 Cyt-b5 PF00173.23 OAJ30089.1 - 5.4e-11 42.1 0.0 7.7e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HTH_Tnp_ISL3 PF13542.1 OAJ30090.1 - 0.038 13.1 0.1 0.075 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF2537 PF10801.3 OAJ30090.1 - 0.067 13.2 1.5 0.18 11.9 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2537) AfsA PF03756.8 OAJ30090.1 - 0.068 12.8 0.2 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 A-factor biosynthesis hotdog domain FAM70 PF14967.1 OAJ30090.1 - 0.32 10.1 3.6 0.26 10.4 1.6 1.5 1 1 0 1 1 1 0 FAM70 protein RVT_2 PF07727.9 OAJ30091.1 - 2.1e-80 269.2 0.0 2.8e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ30091.1 - 6e-26 90.9 0.2 2.4e-25 88.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ30091.1 - 1.7e-05 24.3 0.0 6.6e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain Fer2_BFD PF04324.10 OAJ30091.1 - 0.0041 17.1 0.1 0.0093 16.0 0.1 1.5 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain rve_3 PF13683.1 OAJ30091.1 - 0.018 14.5 0.0 0.083 12.4 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain UBN2 PF14223.1 OAJ30092.1 - 2.3e-08 33.8 0.1 5.3e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 OAJ30092.1 - 1.6e-07 31.3 0.2 6e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2_2 PF14227.1 OAJ30092.1 - 0.00011 21.6 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Foie-gras_1 PF11817.3 OAJ30094.1 - 0.0011 18.4 0.0 0.0032 16.9 0.0 1.8 1 1 0 1 1 1 1 Foie gras liver health family 1 Carn_acyltransf PF00755.15 OAJ30095.1 - 1.3e-155 518.9 0.0 1.8e-155 518.4 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rho_GDI PF02115.12 OAJ30096.1 - 1.6e-49 168.0 0.0 1.9e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor PRKCSH PF07915.8 OAJ30099.1 - 4.5e-12 46.5 0.0 1.1e-07 32.5 0.0 2.8 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein SLAC1 PF03595.12 OAJ30100.1 - 1.4e-64 217.8 46.7 2.2e-64 217.1 32.4 1.3 1 0 0 1 1 1 1 Voltage-dependent anion channel Dimerisation PF08100.6 OAJ30101.1 - 0.062 13.1 0.2 21 5.0 0.0 2.9 1 1 2 3 3 3 0 Dimerisation domain adh_short PF00106.20 OAJ30105.1 - 9.4e-14 51.6 0.5 6.6e-12 45.6 0.4 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ30105.1 - 4.9e-06 26.3 0.0 1.6e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAJ30105.1 - 0.034 14.1 0.1 0.09 12.7 0.1 1.7 1 1 1 2 2 2 0 NADH(P)-binding Shikimate_DH PF01488.15 OAJ30105.1 - 0.11 12.6 0.1 0.29 11.2 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 OAJ30105.1 - 0.2 11.4 2.2 0.16 11.7 0.2 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AhpC-TSA_2 PF13911.1 OAJ30106.1 - 2.5e-15 56.3 0.0 3.5e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 OAJ30106.1 - 0.01 15.4 0.0 0.026 14.0 0.0 1.6 2 0 0 2 2 2 0 Redoxin NAD_binding_7 PF13241.1 OAJ30106.1 - 0.06 13.6 0.0 0.082 13.1 0.0 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding Hydrolase_4 PF12146.3 OAJ30106.1 - 0.092 12.6 0.0 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase RCC1 PF00415.13 OAJ30107.1 - 1.9e-31 108.0 6.2 3e-07 30.5 0.1 6.5 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ30107.1 - 9.8e-21 72.8 12.5 0.0003 20.3 0.0 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 OAJ30107.1 - 4.4e-10 39.0 11.2 4.4e-10 39.0 7.8 1.7 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 OAJ30107.1 - 0.00092 18.8 4.1 0.00092 18.8 2.9 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 OAJ30107.1 - 0.019 14.2 1.3 0.019 14.2 0.9 2.1 3 0 0 3 3 3 0 PHD-finger ADK_lid PF05191.9 OAJ30107.1 - 0.26 10.9 1.8 1.9 8.1 0.6 2.7 2 0 0 2 2 2 0 Adenylate kinase, active site lid C1_1 PF00130.17 OAJ30107.1 - 1.3 8.7 10.7 0.39 10.4 3.7 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Glyco_transf_41 PF13844.1 OAJ30108.1 - 9.2e-97 323.9 0.4 1e-45 155.6 0.0 4.2 4 0 0 4 4 4 4 Glycosyl transferase family 41 TPR_11 PF13414.1 OAJ30108.1 - 4.1e-23 80.8 0.5 6e-09 35.4 0.0 4.8 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 OAJ30108.1 - 5e-19 67.0 0.0 5.6e-05 22.5 0.0 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ30108.1 - 7.8e-18 63.1 0.4 2.9e-05 23.9 0.0 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ30108.1 - 4.2e-14 51.2 0.0 0.0018 18.0 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ30108.1 - 2.4e-12 46.5 0.2 7.7e-05 22.5 0.0 4.9 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ30108.1 - 1.4e-11 43.2 0.0 0.0033 17.0 0.0 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ30108.1 - 4.5e-10 39.2 5.8 0.013 16.1 0.0 5.7 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ30108.1 - 7.4e-07 28.8 1.7 0.06 13.3 0.0 5.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ30108.1 - 2.1e-06 27.9 0.0 0.38 11.1 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ30108.1 - 0.00034 20.1 0.0 5.3 7.0 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ30108.1 - 0.019 15.4 0.0 65 4.3 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MAM33 PF02330.11 OAJ30109.1 - 5.9e-31 107.8 0.0 8.2e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial glycoprotein NESP55 PF06390.7 OAJ30109.1 - 2.9 7.1 13.9 0.18 11.1 6.0 1.5 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF812 PF05667.6 OAJ30110.1 - 0.21 10.0 0.5 0.34 9.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Pyridoxal_deC PF00282.14 OAJ30111.1 - 1.8e-22 79.3 0.0 2.5e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 OAJ30111.1 - 9e-11 41.1 0.0 1.8e-10 40.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 OAJ30111.1 - 0.0057 15.7 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family CHCH PF06747.8 OAJ30112.1 - 4.4e-06 26.4 3.9 8e-06 25.6 2.7 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 OAJ30112.1 - 0.044 13.9 3.5 0.096 12.8 2.4 1.5 1 0 0 1 1 1 0 GCK domain Plasmodium_Vir PF05795.6 OAJ30112.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PQQ_2 PF13360.1 OAJ30112.1 - 0.2 11.0 2.0 0.4 10.0 1.4 1.4 1 1 0 1 1 1 0 PQQ-like domain UPF0220 PF05255.6 OAJ30113.1 - 1.6e-49 167.3 0.0 2.1e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Abhydrolase_5 PF12695.2 OAJ30115.1 - 0.0018 18.0 0.5 0.013 15.2 0.0 2.7 2 1 1 3 3 3 1 Alpha/beta hydrolase family adh_short PF00106.20 OAJ30116.1 - 2.5e-09 37.2 0.7 3.9e-07 30.1 1.0 2.8 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 OAJ30116.1 - 9.9e-08 32.1 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAJ30116.1 - 2.1e-07 30.6 0.0 2.8e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 OAJ30116.1 - 0.0063 15.6 0.0 0.0087 15.2 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) MoCF_biosynth PF00994.19 OAJ30117.1 - 2.1e-34 117.9 0.0 3.6e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain ELO PF01151.13 OAJ30118.1 - 1.7e-57 194.5 7.3 2.2e-57 194.2 5.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family MaoC_dehydratas PF01575.14 OAJ30119.1 - 3.1e-23 81.4 0.0 6.2e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 OAJ30119.1 - 1.1e-08 34.8 0.0 2.7e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Vfa1 PF08432.5 OAJ30120.1 - 8.9e-32 110.5 0.7 3.1e-31 108.7 0.5 1.7 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 PV-1 PF06637.6 OAJ30120.1 - 0.12 10.8 1.7 0.2 10.2 1.2 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) FKBP_N PF01346.13 OAJ30120.1 - 0.15 12.0 3.3 0.27 11.3 2.3 1.3 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Phage_Gp23 PF10669.4 OAJ30120.1 - 1.7 8.7 4.2 2.7 8.0 2.9 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Coprogen_oxidas PF01218.13 OAJ30121.1 - 1.4e-110 368.4 0.7 1.5e-69 233.8 0.0 3.2 2 1 0 2 2 2 2 Coproporphyrinogen III oxidase Saccharop_dh PF03435.13 OAJ30122.1 - 1.6e-23 83.3 0.0 2.3e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 OAJ30122.1 - 1.9e-07 30.7 0.0 3.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ30122.1 - 1.2e-06 28.7 0.0 3.1e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 OAJ30122.1 - 1.5e-05 25.0 0.3 2.7e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 OAJ30122.1 - 0.00016 21.0 0.1 0.00027 20.2 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 OAJ30122.1 - 0.00069 18.3 0.0 0.0014 17.4 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 OAJ30122.1 - 0.0022 17.7 0.1 0.0038 16.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 OAJ30122.1 - 0.0031 17.7 0.0 0.0055 17.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 OAJ30122.1 - 0.0049 16.9 0.0 0.0091 16.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 OAJ30122.1 - 0.024 13.5 0.3 0.13 11.1 0.1 2.3 2 1 0 2 2 2 0 Male sterility protein DapB_N PF01113.15 OAJ30122.1 - 0.097 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Mtr2 PF10429.4 OAJ30123.1 - 0.064 13.0 0.0 0.82 9.4 0.0 2.2 1 1 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 TRAPPC-Trs85 PF12739.2 OAJ30124.1 - 7.3e-94 314.7 0.2 1.1e-93 314.2 0.1 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit CARDB PF07705.6 OAJ30124.1 - 0.025 14.6 0.0 0.065 13.2 0.0 1.7 1 0 0 1 1 1 0 CARDB WD40 PF00400.27 OAJ30125.1 - 1.6e-15 56.2 13.2 0.00065 19.4 0.0 6.1 6 1 0 6 6 6 4 WD domain, G-beta repeat HHH PF00633.18 OAJ30126.1 - 0.019 14.6 0.8 0.037 13.7 0.1 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif Daxx PF03344.10 OAJ30126.1 - 0.73 8.2 17.7 1.2 7.5 12.3 1.2 1 0 0 1 1 1 0 Daxx Family Phospho_p8 PF10195.4 OAJ30126.1 - 4.2 7.3 11.0 33 4.4 7.6 2.5 1 1 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 2-Hacid_dh_C PF02826.14 OAJ30127.1 - 1.1e-51 174.4 0.0 1.9e-51 173.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAJ30127.1 - 2.4e-34 117.6 0.0 3.1e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 OAJ30127.1 - 0.001 18.9 0.0 0.0028 17.5 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase BRCA-2_OB1 PF09103.5 OAJ30128.1 - 3.9e-28 97.5 0.0 7.1e-28 96.6 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 OAJ30128.1 - 4.7e-07 29.5 0.3 7.8e-07 28.8 0.2 1.3 1 0 0 1 1 1 1 BRCA2, helical BRCA2 PF00634.13 OAJ30128.1 - 0.00014 21.0 0.1 0.00029 20.0 0.0 1.4 1 0 0 1 1 1 1 BRCA2 repeat Aldedh PF00171.17 OAJ30129.1 - 1.3e-104 350.1 0.1 1.6e-104 349.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ERCC4 PF02732.10 OAJ30131.1 - 2.5e-24 85.6 0.0 5.5e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain SAM_PNT PF02198.11 OAJ30131.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Pyridox_oxase_2 PF12766.2 OAJ30132.1 - 5.8e-22 77.8 0.0 8.6e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HhH-GPD PF00730.20 OAJ30133.1 - 7e-17 61.6 0.0 1.1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 OAJ30133.1 - 4.8e-08 32.2 0.0 1.6e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 OAJ30133.1 - 2.8 8.2 6.3 6 7.2 4.3 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Tfb2 PF03849.9 OAJ30134.1 - 2.6e-137 457.3 0.0 3.3e-137 457.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 OAJ30134.1 - 6.8e-06 25.8 0.0 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NIF PF03031.13 OAJ30135.1 - 1.9e-20 73.1 0.0 3.1e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 OAJ30135.1 - 0.0034 16.7 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family TAFII55_N PF04658.8 OAJ30136.1 - 2.9e-49 166.6 0.4 2.9e-49 166.6 0.2 1.9 2 0 0 2 2 2 1 TAFII55 protein conserved region DUF4345 PF14248.1 OAJ30137.1 - 0.054 12.9 3.4 0.058 12.8 0.1 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4345) Innate_immun PF12782.2 OAJ30139.1 - 0.31 10.2 8.0 0.35 10.0 5.5 1.0 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Mucin PF01456.12 OAJ30139.1 - 2.5 7.8 9.4 2.6 7.7 6.5 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.4 OAJ30139.1 - 3.9 5.6 5.2 4.2 5.5 3.6 1.0 1 0 0 1 1 1 0 Transmembrane protein APG6 PF04111.7 OAJ30140.1 - 4.6e-103 344.5 0.4 6.2e-103 344.1 0.2 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF972 PF06156.8 OAJ30140.1 - 0.0053 17.0 1.1 0.0053 17.0 0.7 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF972) HAUS-augmin3 PF14932.1 OAJ30140.1 - 0.021 14.0 11.0 0.042 13.0 7.6 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 IncA PF04156.9 OAJ30140.1 - 0.039 13.5 13.6 0.095 12.2 9.5 1.6 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 OAJ30140.1 - 0.051 11.4 4.6 0.073 10.9 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 OAJ30140.1 - 0.071 12.6 6.7 0.14 11.7 4.7 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 OAJ30140.1 - 1.8 7.4 6.9 3.5 6.4 4.8 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Rab5-bind PF09311.6 OAJ30140.1 - 5 6.9 19.5 6.3 6.6 0.2 2.4 2 0 0 2 2 2 0 Rabaptin-like protein Glyco_transf_21 PF13506.1 OAJ30141.1 - 2.6e-22 78.9 0.0 4.6e-09 35.8 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 OAJ30141.1 - 7.3e-15 55.3 0.0 3e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 OAJ30141.1 - 0.0083 15.8 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 PROCN PF08083.6 OAJ30141.1 - 0.089 11.2 0.1 0.14 10.6 0.1 1.2 1 0 0 1 1 1 0 PROCN (NUC071) domain SPC22 PF04573.7 OAJ30142.1 - 4.8e-44 149.6 0.2 5.4e-44 149.5 0.1 1.0 1 0 0 1 1 1 1 Signal peptidase subunit IMS PF00817.15 OAJ30143.1 - 6.9e-44 149.2 0.2 1.2e-43 148.4 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 OAJ30143.1 - 3.1e-16 59.4 0.5 7.1e-16 58.2 0.3 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 OAJ30143.1 - 0.00061 19.6 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif PRA1 PF03208.14 OAJ30144.1 - 1.7e-39 134.6 0.3 2.1e-39 134.3 0.2 1.0 1 0 0 1 1 1 1 PRA1 family protein FA_desaturase PF00487.19 OAJ30144.1 - 4.5 6.6 7.6 60 2.9 5.3 2.0 1 1 0 1 1 1 0 Fatty acid desaturase Sugar_tr PF00083.19 OAJ30145.1 - 5e-39 134.1 15.1 9.2e-39 133.2 10.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ30145.1 - 3.4e-24 85.2 28.5 5e-12 45.2 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_C54 PF03416.14 OAJ30146.1 - 1.2e-83 280.4 0.0 1.4e-82 276.9 0.0 2.3 1 1 0 1 1 1 1 Peptidase family C54 AAA_35 PF14516.1 OAJ30146.1 - 0.83 8.2 0.0 1.2 7.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 OAJ30147.1 - 1.5e-07 32.2 0.1 2.9e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 OAJ30147.1 - 4e-07 30.0 0.0 0.00022 21.1 0.0 2.5 2 0 0 2 2 2 2 Shikimate kinase AAA_18 PF13238.1 OAJ30147.1 - 4.6e-06 26.9 1.3 0.0031 17.8 0.1 2.5 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 OAJ30147.1 - 5.3e-06 26.3 0.2 0.018 14.9 0.0 2.5 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAJ30147.1 - 0.00046 19.6 0.3 0.0023 17.3 0.1 2.1 2 1 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 OAJ30147.1 - 0.00061 19.7 0.3 0.012 15.5 0.0 2.6 2 1 1 3 3 3 1 Cytidylate kinase-like family DUF305 PF03713.8 OAJ30147.1 - 0.0079 16.0 0.9 0.0079 16.0 0.6 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF305) AAA_28 PF13521.1 OAJ30147.1 - 0.009 15.9 0.8 0.036 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 OAJ30147.1 - 0.084 12.5 0.0 0.22 11.2 0.0 1.7 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_29 PF13555.1 OAJ30147.1 - 0.18 11.3 0.4 0.37 10.3 0.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ30147.1 - 1.5 8.7 5.2 1.2 9.0 0.7 2.4 2 1 0 2 2 2 0 AAA ATPase domain Exo_endo_phos PF03372.18 OAJ30148.1 - 1.6e-17 64.2 0.5 2.6e-17 63.5 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Imm1 PF14430.1 OAJ30148.1 - 0.096 12.8 0.0 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Immunity protein Imm1 Cytochrom_D1 PF02239.11 OAJ30148.1 - 0.12 10.6 0.0 0.23 9.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain rve PF00665.21 OAJ30149.1 - 1.8e-22 79.6 0.0 6.3e-22 77.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ30149.1 - 5.8e-07 29.9 0.0 1.4e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ30149.1 - 8.9e-06 25.4 0.0 0.00012 21.8 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease MIP-T3 PF10243.4 OAJ30149.1 - 0.0033 15.9 12.4 0.0054 15.2 8.6 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 RVP PF00077.15 OAJ30149.1 - 0.0048 16.7 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.5 OAJ30149.1 - 0.01 15.2 0.3 0.026 13.9 0.2 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger DUF2201_N PF13203.1 OAJ30149.1 - 0.024 13.8 10.3 0.042 13.0 7.2 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain zf-CCHC PF00098.18 OAJ30149.1 - 0.083 12.8 4.6 0.19 11.7 3.2 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_3 PF13456.1 OAJ30149.1 - 0.15 11.8 0.0 0.43 10.3 0.0 1.8 1 0 0 1 1 1 0 Reverse transcriptase-like DUF605 PF04652.11 OAJ30149.1 - 0.39 10.0 33.0 0.11 11.9 11.0 2.3 2 0 0 2 2 2 0 Vta1 like TFIIF_alpha PF05793.7 OAJ30149.1 - 3.8 5.7 31.2 6.7 4.9 21.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hid1 PF12722.2 OAJ30149.1 - 4.7 4.7 8.2 7.5 4.0 5.7 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF-6 PF01912.13 OAJ30150.1 - 4e-81 270.8 0.3 4.7e-81 270.6 0.2 1.0 1 0 0 1 1 1 1 eIF-6 family Cutinase PF01083.17 OAJ30151.1 - 5.6e-31 107.6 0.2 6.8e-31 107.3 0.2 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ30151.1 - 0.0011 18.6 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ30151.1 - 0.0076 16.0 0.1 0.0092 15.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 OAJ30151.1 - 0.015 14.7 0.0 0.027 13.8 0.0 1.4 1 1 0 1 1 1 0 PE-PPE domain Abhydrolase_6 PF12697.2 OAJ30151.1 - 0.033 14.0 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DPBB_1 PF03330.13 OAJ30153.1 - 2.2e-05 24.3 0.2 8e-05 22.5 0.2 2.1 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel SAPS PF04499.10 OAJ30154.1 - 1e-145 486.0 0.0 4.1e-145 484.0 0.0 2.0 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein HORMA PF02301.13 OAJ30155.1 - 2e-37 128.7 0.7 4.9e-37 127.4 0.0 1.9 2 0 0 2 2 2 1 HORMA domain PHD PF00628.24 OAJ30155.1 - 6e-09 35.4 4.9 1e-08 34.7 3.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 OAJ30155.1 - 0.0011 18.2 2.0 0.0017 17.5 1.4 1.4 1 0 0 1 1 1 1 PHD-finger HTH_24 PF13412.1 OAJ30155.1 - 0.059 12.7 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Lactamase_B PF00753.22 OAJ30156.1 - 1.5e-09 37.8 4.7 3.4e-08 33.3 3.3 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAJ30156.1 - 0.0015 18.1 1.0 0.0032 17.0 0.7 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain FA_hydroxylase PF04116.8 OAJ30157.1 - 5e-14 52.6 16.6 5e-14 52.6 11.5 2.0 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily WD40 PF00400.27 OAJ30158.1 - 8.2e-28 95.2 0.3 4.7e-10 38.9 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 OAJ30158.1 - 0.032 12.5 0.0 0.068 11.4 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain TAF4 PF05236.9 OAJ30159.1 - 5.2e-21 75.0 8.3 1.5e-16 60.4 0.1 3.7 1 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family Y_phosphatase PF00102.22 OAJ30160.1 - 2.3e-29 102.3 0.0 5.2e-14 52.1 0.0 3.3 3 0 0 3 3 3 3 Protein-tyrosine phosphatase DSPc PF00782.15 OAJ30160.1 - 2.7e-06 27.0 0.0 5.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CRISPR_Cse1 PF09481.5 OAJ30161.1 - 0.043 12.5 0.4 0.25 10.0 0.1 1.9 2 0 0 2 2 2 0 CRISPR-associated protein Cse1 (CRISPR_cse1) UvdE PF03851.9 OAJ30162.1 - 4.7e-91 304.6 0.0 6.7e-91 304.1 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE PGA2 PF07543.7 OAJ30162.1 - 5.7 6.7 19.9 0.57 9.9 5.1 2.6 2 0 0 2 2 2 0 Protein trafficking PGA2 Plasmodium_Vir PF05795.6 OAJ30162.1 - 8.7 5.4 6.5 19 4.3 4.5 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein G-alpha PF00503.15 OAJ30163.1 - 9.9e-125 416.2 0.1 1.2e-124 416.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 OAJ30163.1 - 1e-14 54.1 0.1 6.1e-09 35.3 0.0 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ30163.1 - 4.5e-05 22.6 0.1 0.047 12.8 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 OAJ30163.1 - 8e-05 23.1 0.1 0.077 13.4 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 OAJ30163.1 - 0.04 13.4 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DIM1 PF02966.11 OAJ30164.1 - 1.7e-66 221.7 0.1 1.9e-66 221.5 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 OAJ30164.1 - 0.0044 16.6 0.0 0.0056 16.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 OAJ30164.1 - 0.0071 16.3 0.0 0.015 15.2 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ30164.1 - 0.021 14.9 0.0 0.03 14.5 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAJ30164.1 - 0.093 12.8 0.1 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like Preseq_ALAS PF09029.5 OAJ30165.1 - 0.011 15.7 0.4 0.03 14.3 0.0 2.0 2 0 0 2 2 2 0 5-aminolevulinate synthase presequence Calpain_III PF01067.17 OAJ30166.1 - 1.2e-21 76.9 0.0 1.1e-12 47.8 0.0 3.8 4 0 0 4 4 4 2 Calpain large subunit, domain III Peptidase_C2 PF00648.16 OAJ30166.1 - 7.6e-18 64.5 0.0 1.3e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Myb_Cef PF11831.3 OAJ30167.1 - 1.5e-53 181.3 0.0 1.5e-53 181.3 0.0 3.8 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 OAJ30167.1 - 1.4e-22 79.4 4.7 3.3e-11 43.0 0.4 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ30167.1 - 6.2e-20 71.0 8.5 3e-13 49.6 2.7 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain HALZ PF02183.13 OAJ30167.1 - 0.0052 16.4 2.1 0.019 14.6 0.6 2.6 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF217 PF02697.9 OAJ30167.1 - 0.49 10.6 5.4 0.2 11.9 0.5 2.8 2 0 0 2 2 2 0 Uncharacterized ACR, COG1753 DUF3090 PF11290.3 OAJ30167.1 - 0.99 8.8 7.4 0.25 10.7 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) Sec1 PF00995.18 OAJ30168.1 - 7.8e-37 127.1 0.2 9.4e-37 126.8 0.2 1.0 1 0 0 1 1 1 1 Sec1 family F-box PF00646.28 OAJ30169.1 - 1.8e-07 30.6 0.3 3.7e-07 29.6 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ30169.1 - 0.00012 21.7 1.8 0.00016 21.3 0.1 2.1 3 0 0 3 3 3 1 F-box-like HA2 PF04408.18 OAJ30170.1 - 4.8e-28 97.1 0.4 8.6e-28 96.3 0.3 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 OAJ30170.1 - 1.3e-24 86.2 0.0 2.6e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 OAJ30170.1 - 7.5e-11 41.7 0.0 1.6e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ30170.1 - 6.2e-07 29.0 0.0 1.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ30170.1 - 2.4e-06 27.7 0.0 5.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 OAJ30170.1 - 0.012 15.4 0.0 5.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit KaiC PF06745.8 OAJ30170.1 - 0.018 14.1 0.0 0.13 11.3 0.0 2.2 2 0 0 2 2 2 0 KaiC T2SE PF00437.15 OAJ30170.1 - 0.02 13.8 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.17 OAJ30170.1 - 0.026 13.9 0.1 0.1 12.0 0.1 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 OAJ30170.1 - 0.028 14.0 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 OAJ30170.1 - 0.05 13.9 0.0 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 OAJ30170.1 - 0.089 12.3 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRF-TF PF00319.13 OAJ30170.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) ABC_tran PF00005.22 OAJ30170.1 - 0.17 12.1 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Serglycin PF04360.7 OAJ30170.1 - 0.26 11.0 4.0 0.6 9.8 2.8 1.5 1 0 0 1 1 1 0 Serglycin PRELI PF04707.9 OAJ30171.1 - 1.8e-32 112.0 0.0 3.2e-24 85.2 0.0 2.0 2 0 0 2 2 2 2 PRELI-like family Cid2 PF09774.4 OAJ30172.1 - 6.8e-23 81.4 0.1 6.3e-21 75.0 0.1 2.2 1 1 0 1 1 1 1 Caffeine-induced death protein 2 DUF4590 PF15257.1 OAJ30173.1 - 0.05 13.4 0.8 0.065 13.0 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) zf-C3HC4_4 PF15227.1 OAJ30173.1 - 0.63 9.9 5.0 3.1 7.7 3.3 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Furin-like PF00757.15 OAJ30173.1 - 3.3 7.3 10.8 4.1 7.0 7.5 1.1 1 0 0 1 1 1 0 Furin-like cysteine rich region GCR1_C PF12550.3 OAJ30175.1 - 3.7e-19 68.3 2.1 7.2e-19 67.4 1.5 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Bacillus_HBL PF05791.6 OAJ30175.1 - 0.044 13.1 0.1 0.08 12.3 0.1 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Hist_deacetyl PF00850.14 OAJ30176.1 - 6.2e-79 265.5 0.2 1.1e-78 264.6 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain HALZ PF02183.13 OAJ30179.1 - 0.048 13.3 0.1 0.085 12.5 0.1 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper MtrD PF04207.7 OAJ30179.1 - 0.5 9.6 6.0 1.1 8.5 4.2 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D tRNA-synt_2 PF00152.15 OAJ30180.1 - 1.3e-75 254.2 0.0 1.9e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 OAJ30180.1 - 1e-15 57.3 0.1 1.8e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 OAJ30180.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 OAJ30180.1 - 0.0042 16.3 0.2 0.3 10.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF4526 PF15029.1 OAJ30181.1 - 1.6 8.2 5.6 2.4 7.6 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) Abhydrolase_3 PF07859.8 OAJ30182.1 - 1.3e-36 126.1 1.6 3.7e-30 105.0 0.9 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 OAJ30182.1 - 7.2e-11 41.4 0.2 1.5e-10 40.4 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 OAJ30182.1 - 0.00037 20.2 1.5 0.00056 19.6 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 OAJ30182.1 - 0.17 10.3 0.2 2.5 6.4 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) zf-C2H2_2 PF12756.2 OAJ30183.1 - 7.8e-36 122.2 1.8 7.3e-28 96.6 0.0 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 OAJ30183.1 - 6.7e-08 32.4 12.7 7.9e-06 25.8 0.4 3.4 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAJ30183.1 - 2.9e-07 30.4 5.3 3.4e-07 30.2 0.5 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type AKAP95 PF04988.7 OAJ30183.1 - 0.0033 17.1 0.2 0.0061 16.3 0.1 1.4 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.21 OAJ30183.1 - 0.025 14.9 18.1 0.029 14.6 0.3 4.5 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 OAJ30183.1 - 0.077 12.9 5.2 21 5.1 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger NOA36 PF06524.7 OAJ30183.1 - 0.2 10.8 3.8 10 5.2 0.0 2.3 2 0 0 2 2 2 0 NOA36 protein zf-C2H2_4 PF13894.1 OAJ30183.1 - 0.28 11.5 11.9 1.9 9.0 0.1 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-DBF PF07535.7 OAJ30183.1 - 0.46 10.1 0.0 0.46 10.1 0.0 2.3 3 0 0 3 3 3 0 DBF zinc finger Macoilin PF09726.4 OAJ30183.1 - 7.1 4.7 13.7 13 3.9 9.5 1.4 1 0 0 1 1 1 0 Transmembrane protein Prp31_C PF09785.4 OAJ30185.1 - 1.1e-37 129.2 6.9 1.1e-37 129.2 4.8 2.0 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 OAJ30185.1 - 2.9e-36 124.0 0.4 5.5e-36 123.1 0.3 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 OAJ30185.1 - 1.6e-20 72.6 0.6 3.7e-20 71.4 0.0 2.0 2 0 0 2 2 2 1 NOSIC (NUC001) domain Daxx PF03344.10 OAJ30185.1 - 0.28 9.6 14.3 0.0074 14.8 5.3 1.6 2 0 0 2 2 2 0 Daxx Family NOA36 PF06524.7 OAJ30185.1 - 0.89 8.7 13.6 1.6 7.9 9.4 1.3 1 0 0 1 1 1 0 NOA36 protein F-box-like PF12937.2 OAJ30186.1 - 0.00067 19.3 0.1 0.0025 17.5 0.1 2.0 1 0 0 1 1 1 1 F-box-like Toxin_20 PF08089.6 OAJ30187.1 - 4.7 7.1 9.9 0.83 9.6 1.5 3.0 3 0 0 3 3 3 0 Huwentoxin-II family DUF3437 PF11919.3 OAJ30188.1 - 1e-30 105.2 0.5 3.8e-29 100.2 0.0 3.7 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.1 OAJ30188.1 - 0.00011 22.3 0.3 0.029 14.6 0.0 4.3 4 2 1 5 5 5 1 HEAT repeats HEAT PF02985.17 OAJ30188.1 - 0.00058 19.7 0.9 0.056 13.5 0.0 4.6 5 0 0 5 5 5 1 HEAT repeat DUF1546 PF07571.8 OAJ30188.1 - 0.013 15.6 0.1 1.3 9.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1546) Npa1 PF11707.3 OAJ30189.1 - 5e-66 222.9 0.0 1.1e-41 142.9 0.0 3.6 4 1 0 4 4 4 2 Ribosome 60S biogenesis N-terminal HEAT PF02985.17 OAJ30189.1 - 0.15 12.2 2.8 8.9 6.6 0.1 4.7 4 0 0 4 4 4 0 HEAT repeat Na_Ca_ex PF01699.19 OAJ30190.1 - 4.7e-45 152.6 29.8 2.1e-23 82.4 6.4 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Lactonase PF10282.4 OAJ30191.1 - 2e-67 227.7 0.0 2.4e-67 227.4 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NIF PF03031.13 OAJ30194.1 - 1.1e-07 31.7 0.0 0.0062 16.2 0.0 3.5 4 0 0 4 4 4 2 NLI interacting factor-like phosphatase GNAT_acetyltr_2 PF13718.1 OAJ30195.1 - 3.3e-64 215.8 0.0 5.2e-64 215.1 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 OAJ30195.1 - 1.4e-51 174.6 0.0 2.4e-51 173.8 0.0 1.4 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 OAJ30195.1 - 7.7e-32 108.8 0.0 1.7e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 OAJ30195.1 - 1.8e-24 85.7 0.1 5.4e-24 84.2 0.1 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Endonuclease_NS PF01223.18 OAJ30196.1 - 3.3e-51 173.8 0.0 4.6e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease rve PF00665.21 OAJ30197.1 - 1.9e-06 27.9 0.1 3.3e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain DUF3437 PF11919.3 OAJ30198.1 - 9.1e-20 70.1 0.0 4.4e-19 67.9 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.1 OAJ30198.1 - 4.7e-05 23.5 0.1 0.072 13.3 0.0 4.2 2 1 1 3 3 3 2 HEAT repeats DUF2435 PF10363.4 OAJ30198.1 - 0.037 13.9 0.1 0.096 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) adh_short PF00106.20 OAJ30199.1 - 1.5e-28 99.7 1.7 1.5e-28 99.7 1.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ30199.1 - 3.9e-27 95.5 0.3 5e-27 95.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ30199.1 - 3.3e-12 46.4 2.6 3.3e-12 46.4 1.8 2.4 1 1 1 2 2 2 1 KR domain Exo_endo_phos PF03372.18 OAJ30200.1 - 2.3e-14 53.9 0.3 1.9e-10 41.1 0.0 2.3 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family LURAP PF14854.1 OAJ30201.1 - 4.8 6.9 5.3 8.7 6.0 0.7 2.4 2 1 0 2 2 2 0 Leucine rich adaptor protein HSBP1 PF06825.7 OAJ30202.1 - 5.6e-11 41.8 0.1 7.9e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 HAD_2 PF13419.1 OAJ30203.1 - 2.6e-23 83.1 0.5 4.4e-23 82.3 0.3 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 OAJ30203.1 - 1.3e-14 53.4 0.1 4.6e-06 26.2 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box PF00646.28 OAJ30203.1 - 6.1e-06 25.7 0.1 1.7e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ30203.1 - 0.00026 20.6 0.1 0.00063 19.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like COesterase PF00135.23 OAJ30204.1 - 4.5e-109 365.5 0.0 6.5e-109 365.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ30204.1 - 3.5e-10 39.8 0.2 1.3e-09 37.9 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold CNH PF00780.17 OAJ30205.1 - 1.2e-06 28.1 0.0 5.3e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 CNH domain Vps39_2 PF10367.4 OAJ30205.1 - 1.6e-06 28.2 2.7 3.7e-06 27.0 1.9 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 OAJ30205.1 - 0.017 15.1 0.4 0.072 13.1 0.0 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_14 PF13428.1 OAJ30205.1 - 0.11 13.2 11.3 35 5.4 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DNA_pol_E_B PF04042.11 OAJ30206.1 - 6.2e-46 156.2 0.2 8.6e-46 155.8 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_2 PF12850.2 OAJ30206.1 - 0.0025 17.6 0.0 0.033 14.0 0.0 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FleQ PF06490.6 OAJ30206.1 - 0.093 12.8 0.0 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ HAD PF12710.2 OAJ30207.1 - 3.4e-13 50.2 0.0 4.4e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 OAJ30207.1 - 1.2e-06 28.0 0.0 6.7e-06 25.6 0.0 1.9 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.7 OAJ30207.1 - 0.00013 21.1 0.4 0.0012 18.0 0.1 2.0 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.21 OAJ30207.1 - 0.00091 19.6 0.6 0.0044 17.4 0.0 2.1 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 OAJ30207.1 - 0.0011 19.2 0.1 0.0085 16.3 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Pkinase PF00069.20 OAJ30208.1 - 4.6e-66 222.6 0.0 4.6e-66 222.6 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ30208.1 - 6.2e-43 146.7 0.0 6.2e-43 146.7 0.0 1.8 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ30208.1 - 2.7e-07 29.8 0.0 1.8e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Spore_coat_CotO PF14153.1 OAJ30208.1 - 0.015 14.7 15.7 0.12 11.8 3.0 2.4 2 0 0 2 2 2 0 Spore coat protein CotO zf-DHHC PF01529.15 OAJ30208.1 - 0.11 11.9 1.2 1 8.6 0.1 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Ycf1 PF05758.7 OAJ30208.1 - 0.38 8.4 3.3 1.4 6.5 0.1 2.0 2 0 0 2 2 2 0 Ycf1 Seadorna_VP7 PF07387.6 OAJ30208.1 - 2.1 7.0 0.0 3.3 6.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 p450 PF00067.17 OAJ30210.1 - 1.8e-49 168.5 0.0 3.7e-48 164.1 0.0 2.8 1 1 0 1 1 1 1 Cytochrome P450 Pyridoxal_deC PF00282.14 OAJ30211.1 - 4.6e-63 212.9 0.0 7e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 OAJ30211.1 - 0.0025 16.6 0.0 0.0039 16.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Pil1 PF13805.1 OAJ30212.1 - 3.4e-26 91.9 0.1 9.5e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 Eisosome component PIL1 BAF1_ABF1 PF04684.8 OAJ30212.1 - 0.034 13.0 12.3 0.066 12.0 8.5 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GMP_synt_C PF00958.17 OAJ30213.1 - 2.7e-41 139.1 0.0 5.2e-41 138.2 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 OAJ30213.1 - 4.8e-36 124.0 0.0 7.9e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 OAJ30213.1 - 5.4e-11 41.8 0.1 1e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 OAJ30213.1 - 1e-09 38.1 0.0 2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 OAJ30213.1 - 0.0006 18.4 0.2 0.001 17.6 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 OAJ30213.1 - 0.0011 18.4 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 OAJ30213.1 - 0.0018 17.8 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 OAJ30213.1 - 0.016 14.4 0.0 0.24 10.6 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.15 OAJ30213.1 - 0.049 13.1 0.1 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 PP-loop family Arginosuc_synth PF00764.14 OAJ30213.1 - 0.062 12.3 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase DUF2392 PF10288.4 OAJ30213.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) RA PF00788.18 OAJ30215.1 - 1.3e-12 47.9 2.8 4.3e-10 39.9 0.0 3.1 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 OAJ30215.1 - 7.3e-07 28.4 0.0 1.5e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ30215.1 - 0.0011 18.4 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain MRI PF15325.1 OAJ30216.1 - 0.39 11.7 4.9 0.51 11.3 3.4 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection Macoilin PF09726.4 OAJ30216.1 - 8.1 4.5 8.1 8.4 4.5 5.6 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF515 PF04415.7 OAJ30217.1 - 0.27 9.4 17.2 0.36 9.0 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) PAP1 PF08601.5 OAJ30217.1 - 0.38 10.3 8.3 0.45 10.1 5.8 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Pex14_N PF04695.8 OAJ30217.1 - 5.2 7.1 11.4 9.2 6.3 7.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SRP54 PF00448.17 OAJ30218.1 - 3.1e-75 251.9 0.3 3.1e-75 251.9 0.2 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 OAJ30218.1 - 3e-24 85.2 0.7 1.5e-21 76.6 0.0 3.9 2 1 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.14 OAJ30218.1 - 1.3e-11 44.4 1.3 2.6e-11 43.4 0.9 1.5 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 OAJ30218.1 - 2e-05 24.4 0.0 5.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 OAJ30218.1 - 2.2e-05 23.9 0.5 0.00011 21.7 0.4 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 OAJ30218.1 - 0.0018 17.7 0.1 0.0053 16.1 0.1 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 OAJ30218.1 - 0.0029 17.5 0.1 1.4 8.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain MobB PF03205.9 OAJ30218.1 - 0.003 17.2 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 OAJ30218.1 - 0.0068 16.5 0.2 0.023 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 OAJ30218.1 - 0.013 15.1 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.1 OAJ30218.1 - 0.019 15.8 0.0 0.044 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAJ30218.1 - 0.083 13.1 0.0 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 OAJ30218.1 - 0.59 9.5 2.9 0.88 8.9 0.2 2.5 2 1 0 2 2 2 0 AAA domain FAD_binding_7 PF03441.9 OAJ30219.1 - 6.4e-63 212.5 0.1 9.1e-63 212.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 OAJ30219.1 - 2.9e-20 72.6 0.0 5.2e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase HSA PF07529.8 OAJ30220.1 - 3.6e-16 58.7 4.5 3.6e-16 58.7 3.1 4.3 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 OAJ30220.1 - 3.5e-07 30.2 0.0 9.1e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Prefoldin PF02996.12 OAJ30221.1 - 2.1e-26 91.9 0.1 2.5e-26 91.6 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit GAS PF13851.1 OAJ30221.1 - 0.0054 15.9 0.8 0.32 10.1 0.3 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding CCDC155 PF14662.1 OAJ30221.1 - 0.012 15.2 0.7 0.05 13.1 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Prefoldin_2 PF01920.15 OAJ30221.1 - 0.016 14.9 0.2 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit Cep57_MT_bd PF06657.8 OAJ30221.1 - 0.075 12.9 0.3 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Apolipoprotein PF01442.13 OAJ30221.1 - 0.12 11.9 2.4 6 6.3 0.0 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4200 PF13863.1 OAJ30221.1 - 0.27 11.1 1.9 5.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF1192 PF06698.6 OAJ30221.1 - 0.53 10.1 3.1 1.1 9.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) GATA PF00320.22 OAJ30222.1 - 1.1e-26 91.8 21.1 5.7e-14 51.1 3.2 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 OAJ30222.1 - 1.6e-08 33.9 0.2 2.8e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 OAJ30222.1 - 0.0016 17.6 6.3 0.074 12.3 0.9 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding NMD3 PF04981.8 OAJ30222.1 - 0.34 9.9 3.0 2.4 7.1 0.0 2.2 2 0 0 2 2 2 0 NMD3 family DZR PF12773.2 OAJ30222.1 - 0.9 9.4 10.6 2 8.2 0.7 2.8 1 1 2 3 3 3 0 Double zinc ribbon eIF-5_eIF-2B PF01873.12 OAJ30222.1 - 1.4 8.5 7.3 1.7 8.3 0.6 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.7 OAJ30222.1 - 7.8 6.3 9.3 1.1 9.0 0.2 3.1 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ubiquitin PF00240.18 OAJ30223.1 - 2e-34 116.8 1.1 2.7e-34 116.3 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 OAJ30223.1 - 8.9e-20 70.1 0.8 1.3e-19 69.6 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.11 OAJ30223.1 - 3.3e-10 39.6 5.0 6e-10 38.8 3.4 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_2 PF14560.1 OAJ30223.1 - 1.2e-05 25.4 0.2 4.1e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAJ30223.1 - 0.00016 21.3 0.7 0.00023 20.9 0.0 1.6 2 0 0 2 2 2 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 OAJ30223.1 - 0.0038 17.0 0.5 0.015 15.1 0.1 2.1 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 OAJ30223.1 - 0.0091 16.1 0.1 0.011 15.9 0.1 1.3 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Pet191_N PF10203.4 OAJ30224.1 - 1.1e-23 83.0 1.8 1.2e-23 82.8 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Lysine_decarbox PF03641.9 OAJ30225.1 - 7.3e-34 116.4 0.0 1e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase HMG-CoA_red PF00368.13 OAJ30226.1 - 3.1e-157 523.0 8.2 4.3e-157 522.5 5.7 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 OAJ30226.1 - 3.8e-20 71.8 1.0 1e-09 38.0 0.1 2.6 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 OAJ30226.1 - 9.3e-07 27.1 3.1 0.0012 16.8 0.0 2.2 2 0 0 2 2 2 2 Patched family WD40 PF00400.27 OAJ30227.1 - 9e-09 34.8 3.3 0.0092 15.8 0.1 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat PQQ_2 PF13360.1 OAJ30227.1 - 0.0026 17.2 0.0 0.0062 16.0 0.0 1.6 1 0 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 OAJ30227.1 - 0.014 15.6 0.2 0.073 13.3 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain Kelch_6 PF13964.1 OAJ30227.1 - 0.025 14.7 0.0 12 6.3 0.0 2.8 2 0 0 2 2 2 0 Kelch motif Mito_fiss_reg PF05308.6 OAJ30227.1 - 1.4 8.2 9.9 0.34 10.2 3.8 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator Abhydrolase_4 PF08386.5 OAJ30228.1 - 1.1e-12 47.7 0.0 3.4e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 OAJ30228.1 - 2.6e-09 36.9 1.0 4.9e-08 32.8 0.7 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ30228.1 - 2e-06 27.8 6.7 3.1e-05 23.9 4.6 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ30228.1 - 0.0013 18.4 0.0 0.0056 16.4 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1729 PF08354.5 OAJ30229.1 - 1.1e-21 76.3 0.1 4.5e-21 74.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) AhpC-TSA PF00578.16 OAJ30232.1 - 3.8e-06 26.5 0.0 6e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.1 OAJ30232.1 - 4.1e-06 26.6 0.0 6.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 OAJ30232.1 - 1.4e-05 24.6 0.0 0.00015 21.3 0.0 2.0 2 0 0 2 2 2 1 Redoxin EamA PF00892.15 OAJ30233.1 - 2.3e-22 79.3 32.6 2.2e-15 56.8 4.3 3.9 3 1 1 4 4 4 3 EamA-like transporter family EmrE PF13536.1 OAJ30233.1 - 2.9e-08 33.8 4.7 2.9e-08 33.8 3.2 4.1 3 1 2 5 5 5 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 OAJ30233.1 - 0.00079 18.6 1.2 0.002 17.2 0.8 1.6 1 0 0 1 1 1 1 Nucleotide-sugar transporter DUF1516 PF07457.6 OAJ30233.1 - 0.046 13.8 0.3 0.046 13.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) TPT PF03151.11 OAJ30233.1 - 0.39 10.3 19.7 0.32 10.6 2.7 3.2 3 1 0 3 3 3 0 Triose-phosphate Transporter family DUF3021 PF11457.3 OAJ30233.1 - 1.4 8.7 5.5 0.25 11.2 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) AA_permease PF00324.16 OAJ30234.1 - 1.4e-104 350.1 28.0 1.7e-104 349.8 19.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAJ30234.1 - 1.4e-36 125.9 31.0 1.7e-36 125.6 21.5 1.0 1 0 0 1 1 1 1 Amino acid permease PAP2_3 PF14378.1 OAJ30234.1 - 0.023 14.2 3.3 0.057 12.9 0.4 2.6 1 1 2 3 3 3 0 PAP2 superfamily DUF3348 PF11828.3 OAJ30237.1 - 0.012 14.9 0.6 0.027 13.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3348) Apolipoprotein PF01442.13 OAJ30237.1 - 0.023 14.2 1.2 0.059 12.8 0.8 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2316 PF10078.4 OAJ30237.1 - 0.043 13.8 0.6 3.7 7.6 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) COG5 PF10392.4 OAJ30237.1 - 0.088 12.7 0.1 4.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF4481 PF14800.1 OAJ30238.1 - 0.067 12.0 0.6 0.32 9.8 0.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4481) Sigma70_ner PF04546.8 OAJ30238.1 - 0.14 11.7 7.7 0.13 11.8 3.4 2.4 3 0 0 3 3 3 0 Sigma-70, non-essential region Fib_alpha PF08702.5 OAJ30238.1 - 0.17 11.9 3.2 0.27 11.3 0.0 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family HSP70 PF00012.15 OAJ30240.1 - 3.8e-29 101.0 0.1 5.5e-29 100.5 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein RNA_pol_I_A49 PF06870.7 OAJ30240.1 - 2.6e-08 32.8 0.0 4.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Peptidase_U40 PF10464.4 OAJ30240.1 - 0.064 12.6 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Peptidase U40 DUF1455 PF07306.6 OAJ30241.1 - 0.074 13.1 0.9 0.22 11.5 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1455) DASH_Hsk3 PF08227.6 OAJ30242.1 - 0.025 14.7 0.1 0.077 13.2 0.1 1.8 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like KKLCAg1 PF15204.1 OAJ30243.1 - 0.06 13.3 0.1 0.065 13.2 0.0 1.1 1 0 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 DUF3818 PF12825.2 OAJ30244.1 - 2.9e-117 391.1 0.0 4.1e-117 390.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PX PF00787.19 OAJ30244.1 - 0.0034 17.1 0.0 0.011 15.5 0.0 1.9 1 1 0 1 1 1 1 PX domain NOA36 PF06524.7 OAJ30244.1 - 0.34 10.1 3.0 0.85 8.8 2.1 1.6 1 0 0 1 1 1 0 NOA36 protein Methyltransf_26 PF13659.1 OAJ30245.1 - 4.6e-13 49.2 0.0 7.1e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ30245.1 - 2.7e-08 33.5 0.0 4.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ30245.1 - 5.6e-08 33.3 0.0 1.1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 OAJ30245.1 - 2.9e-06 26.5 0.0 3.9e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_25 PF13649.1 OAJ30245.1 - 6.3e-06 26.4 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ30245.1 - 0.00012 21.4 0.4 0.0072 15.7 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase small domain UPF0020 PF01170.13 OAJ30245.1 - 0.0012 18.4 0.2 0.046 13.2 0.0 2.1 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 OAJ30245.1 - 0.0097 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 OAJ30245.1 - 0.012 14.7 0.1 0.027 13.6 0.1 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_10 PF05971.7 OAJ30245.1 - 0.025 13.7 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF890) Methyltransf_15 PF09445.5 OAJ30245.1 - 0.035 13.6 0.0 0.073 12.6 0.0 1.6 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.1 OAJ30245.1 - 0.07 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ30245.1 - 0.1 13.0 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Vps16_C PF04840.7 OAJ30246.1 - 9.8e-67 225.1 1.4 3.5e-36 124.7 0.0 3.1 3 0 0 3 3 3 3 Vps16, C-terminal region Vps16_N PF04841.8 OAJ30246.1 - 3.4e-47 160.9 0.0 1.2e-20 73.4 0.0 4.2 4 0 0 4 4 4 4 Vps16, N-terminal region Nop10p PF04135.7 OAJ30246.1 - 3.2e-19 68.3 2.1 9.7e-19 66.8 0.1 2.4 2 0 0 2 2 2 1 Nucleolar RNA-binding protein, Nop10p family PseudoU_synth_1 PF01416.15 OAJ30248.1 - 2.9e-21 75.8 0.0 2.5e-11 43.9 0.0 2.8 3 0 0 3 3 3 2 tRNA pseudouridine synthase WLM PF08325.5 OAJ30251.1 - 4.7e-40 137.4 0.0 9e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 WLM domain Casc1 PF12366.3 OAJ30252.1 - 2.2 7.7 10.6 0.61 9.5 0.8 2.2 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 CBF PF03914.12 OAJ30254.1 - 1.6e-34 118.7 0.0 6.4e-34 116.7 0.0 2.0 2 0 0 2 2 2 1 CBF/Mak21 family BLVR PF06375.6 OAJ30254.1 - 1.3 8.8 7.7 1.8 8.3 1.9 2.6 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Sas10_Utp3 PF04000.10 OAJ30255.1 - 1.5e-08 34.7 0.5 3.5e-08 33.5 0.3 1.7 1 1 0 1 1 1 1 Sas10/Utp3/C1D family HIRAN PF08797.6 OAJ30256.1 - 1.8e-19 69.5 0.0 3.4e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Ribosomal_L23eN PF03939.8 OAJ30256.1 - 0.029 14.3 5.9 0.084 12.9 4.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain Acetyltransf_1 PF00583.19 OAJ30257.1 - 7.2e-09 35.5 0.0 3.8e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ30257.1 - 0.00011 22.3 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAJ30257.1 - 0.0051 16.6 0.0 0.021 14.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Nop14 PF04147.7 OAJ30257.1 - 0.0099 13.8 19.5 0.01 13.7 1.7 3.0 3 0 0 3 3 3 2 Nop14-like family Acetyltransf_8 PF13523.1 OAJ30257.1 - 0.031 14.1 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ30257.1 - 0.14 11.9 0.0 6.7 6.5 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein Rota_VP2 PF05087.7 OAJ30257.1 - 2.6 5.8 3.2 3.9 5.2 2.2 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein Mucin PF01456.12 OAJ30257.1 - 7.7 6.2 31.5 0.053 13.3 4.0 3.6 3 0 0 3 3 3 0 Mucin-like glycoprotein alpha-hel2 PF14456.1 OAJ30257.1 - 9.1 4.9 9.8 0.3 9.8 2.4 1.7 2 0 0 2 2 2 0 Alpha-helical domain 2 PAP2 PF01569.16 OAJ30258.1 - 1.7e-12 47.1 3.5 2.7e-12 46.4 2.4 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 OAJ30258.1 - 0.039 13.6 0.1 0.039 13.6 0.1 2.5 3 1 0 3 3 3 0 Divergent PAP2 family DUF2517 PF10725.4 OAJ30258.1 - 0.078 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) DUF1768 PF08719.6 OAJ30259.1 - 1.2e-18 67.3 1.2 2.7e-12 46.7 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF1768) GCS PF03074.11 OAJ30260.1 - 6.8e-149 495.9 0.0 1.6e-123 412.4 0.0 2.8 3 0 0 3 3 3 2 Glutamate-cysteine ligase TFIIA PF03153.8 OAJ30260.1 - 0.92 9.3 4.2 2 8.2 2.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PBP1_TM PF14812.1 OAJ30260.1 - 3.1 8.1 7.2 13 6.2 5.0 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIE_alpha PF02002.12 OAJ30261.1 - 5.8e-09 35.4 0.0 1.1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit zf-C2H2_6 PF13912.1 OAJ30261.1 - 0.12 12.2 0.1 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C3HC4_3 PF13920.1 OAJ30262.1 - 0.057 13.1 0.2 0.083 12.5 0.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.2 OAJ30263.1 - 2.9e-21 75.5 0.1 2.8e-09 37.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ30263.1 - 6.5e-21 74.3 0.9 4.4e-12 46.1 0.1 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ30263.1 - 1.4e-17 63.2 0.5 2.6e-08 33.8 0.0 3.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 OAJ30263.1 - 1.5e-17 62.4 0.0 3.8e-07 29.5 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 OAJ30263.1 - 1e-15 56.2 0.5 0.00019 21.3 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat KilA-N PF04383.8 OAJ30263.1 - 7.6e-06 25.5 1.0 5e-05 22.8 0.1 2.4 2 1 0 2 2 2 1 KilA-N domain PTPlike_phytase PF14566.1 OAJ30263.1 - 0.12 12.4 0.0 22 5.0 0.0 2.5 2 0 0 2 2 2 0 Inositol hexakisphosphate BTB PF00651.26 OAJ30263.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain zf-C3HC4_3 PF13920.1 OAJ30264.1 - 4.1e-10 39.1 4.2 6.5e-10 38.5 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ30264.1 - 1.1e-05 25.3 5.1 2.2e-05 24.3 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ30264.1 - 1.6e-05 24.4 4.2 2.8e-05 23.6 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ30264.1 - 2.5e-05 24.0 5.1 4.8e-05 23.1 3.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAJ30264.1 - 0.00072 19.2 4.0 0.0013 18.3 2.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 OAJ30264.1 - 1.6 8.3 4.1 4.2 7.0 2.8 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RIO1 PF01163.17 OAJ30265.1 - 1.7e-38 131.8 0.1 1.6e-26 92.8 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 OAJ30265.1 - 7.2e-29 99.6 0.0 1.5e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 OAJ30265.1 - 2.8e-07 30.5 1.1 0.00039 20.2 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 OAJ30265.1 - 0.0075 15.3 0.0 0.049 12.6 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MarR_2 PF12802.2 OAJ30265.1 - 0.029 14.0 0.2 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 MarR family Epimerase PF01370.16 OAJ30266.1 - 1.5e-19 70.3 0.0 2.3e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAJ30266.1 - 1.2e-14 53.7 0.0 6.8e-14 51.2 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 OAJ30266.1 - 1.4e-09 37.2 0.0 2.7e-08 33.0 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein TcpF PF06340.6 OAJ30266.1 - 0.0012 17.9 0.1 0.002 17.3 0.1 1.3 1 0 0 1 1 1 1 Vibrio cholerae toxin co-regulated pilus biosynthesis protein F RmlD_sub_bind PF04321.12 OAJ30266.1 - 0.016 14.0 0.0 0.042 12.7 0.0 1.7 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 OAJ30266.1 - 0.15 11.2 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family muHD PF10291.4 OAJ30267.1 - 5.4e-38 130.6 0.0 8.6e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 OAJ30267.1 - 7e-07 29.3 0.1 2.6e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Adap_comp_sub PF00928.16 OAJ30267.1 - 1.3e-05 24.4 0.0 7.9e-05 21.8 0.0 1.9 1 1 0 1 1 1 1 Adaptor complexes medium subunit family HrpB7 PF09486.5 OAJ30267.1 - 0.0029 17.5 2.8 0.0067 16.3 1.9 1.5 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) 4F5 PF04419.9 OAJ30269.1 - 5.8e-10 39.7 8.5 5.8e-10 39.7 5.9 2.2 2 0 0 2 2 2 1 4F5 protein family Phage_tail_2 PF06199.6 OAJ30269.1 - 0.078 13.0 0.1 0.082 12.9 0.1 1.1 1 0 0 1 1 1 0 Phage major tail protein 2 CdhC PF03598.10 OAJ30269.1 - 0.11 10.9 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit RPA_C PF08784.6 OAJ30270.1 - 1.8e-09 37.9 0.1 1.8e-09 37.9 0.1 2.2 3 0 0 3 3 3 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 OAJ30270.1 - 2.4e-09 36.9 0.1 4e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HTH_20 PF12840.2 OAJ30270.1 - 0.00052 19.7 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain BOF PF04076.8 OAJ30270.1 - 0.055 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein DOMON PF03351.12 OAJ30270.1 - 0.068 13.1 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 DOMON domain HTH_27 PF13463.1 OAJ30270.1 - 0.12 12.6 0.0 0.4 11.0 0.0 2.0 1 0 0 1 1 1 0 Winged helix DNA-binding domain PRP4 PF08799.6 OAJ30271.1 - 0.14 11.4 0.2 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Chs3p PF12271.3 OAJ30272.1 - 5.9e-26 91.1 18.1 1.1e-24 86.9 6.4 3.0 2 1 0 2 2 2 2 Chitin synthase III catalytic subunit Soyouz_module PF14313.1 OAJ30272.1 - 0.00011 21.6 0.5 0.00056 19.4 0.0 2.1 2 0 0 2 2 2 1 N-terminal region of Paramyxovirinae phosphoprotein (P) HAMP PF00672.20 OAJ30272.1 - 0.032 14.4 0.0 0.098 12.8 0.0 1.8 1 0 0 1 1 1 0 HAMP domain WASH-7_mid PF14744.1 OAJ30272.1 - 0.084 11.7 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 WASH complex subunit 7 PsbX PF06596.6 OAJ30272.1 - 6.2 6.5 8.0 1.2 8.9 0.2 3.2 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) XPG_I PF00867.13 OAJ30273.1 - 4.7e-16 58.6 0.0 2.3e-15 56.4 0.0 2.1 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 OAJ30273.1 - 4.1e-06 26.9 0.0 1.3e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain Ribul_P_3_epim PF00834.14 OAJ30274.1 - 7.1e-69 230.9 0.0 8.6e-69 230.6 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 OAJ30274.1 - 0.00067 19.2 0.0 0.0026 17.2 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain PcrB PF01884.12 OAJ30274.1 - 0.073 12.3 0.1 0.25 10.5 0.0 1.9 1 1 0 1 1 1 0 PcrB family Abhydrolase_5 PF12695.2 OAJ30275.1 - 5.7e-16 58.5 0.1 9e-16 57.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ30275.1 - 2.3e-12 47.2 3.5 4.7e-12 46.2 2.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAJ30275.1 - 6.7e-11 42.1 0.1 9.3e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAJ30275.1 - 0.0031 16.7 0.2 0.015 14.5 0.1 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 OAJ30275.1 - 0.0033 16.9 0.1 0.01 15.4 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 OAJ30275.1 - 0.026 14.7 0.1 0.053 13.7 0.1 1.5 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.3 OAJ30275.1 - 0.036 13.9 0.1 0.33 10.8 0.0 2.4 2 0 0 2 2 2 0 Putative lysophospholipase MOZART1 PF12554.3 OAJ30276.1 - 2.6e-15 55.5 0.1 3.3e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated UPF0181 PF03701.9 OAJ30276.1 - 0.16 11.2 0.2 0.33 10.3 0.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0181) Syja_N PF02383.13 OAJ30278.1 - 1.2e-72 244.4 0.0 2.4e-72 243.4 0.0 1.5 1 1 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 OAJ30278.1 - 1.3e-27 95.4 0.0 7.8e-27 92.9 0.0 2.0 2 0 0 2 2 2 1 Inositol phosphatase FAD_binding_3 PF01494.14 OAJ30279.1 - 2.6e-22 79.3 0.2 5.8e-12 45.3 0.0 3.1 2 2 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAJ30279.1 - 9.9e-07 27.9 0.1 3.6e-06 26.1 0.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ30279.1 - 8.2e-06 25.7 0.0 6.2e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAJ30279.1 - 3.4e-05 24.1 0.0 0.00024 21.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 OAJ30279.1 - 0.0008 18.3 0.0 0.095 11.5 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase ApbA PF02558.11 OAJ30279.1 - 0.00086 18.7 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 OAJ30279.1 - 0.00092 17.7 0.0 0.0014 17.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.13 OAJ30279.1 - 0.0023 17.6 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 OAJ30279.1 - 0.0043 15.9 0.0 0.0063 15.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 OAJ30279.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 OAJ30279.1 - 0.031 14.2 0.0 0.095 12.7 0.0 1.9 1 0 0 1 1 1 0 NADH(P)-binding FAD_oxidored PF12831.2 OAJ30279.1 - 0.06 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.16 OAJ30279.1 - 0.062 13.1 0.2 0.17 11.7 0.2 1.7 1 0 0 1 1 1 0 ThiF family NAD_Gly3P_dh_N PF01210.18 OAJ30279.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 OAJ30279.1 - 0.091 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 OAJ30279.1 - 0.11 11.5 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 OAJ30279.1 - 0.13 10.8 0.0 0.5 8.9 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase MAT1 PF06391.8 OAJ30280.1 - 1.5e-36 125.9 5.1 2.2e-36 125.3 3.5 1.3 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 OAJ30280.1 - 0.00015 21.2 8.1 0.00034 20.1 5.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ30280.1 - 0.00073 19.2 7.4 0.0021 17.7 5.2 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-ISL3 PF14690.1 OAJ30280.1 - 0.008 16.1 1.3 0.14 12.1 0.0 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C3HC4_2 PF13923.1 OAJ30280.1 - 0.014 15.4 10.2 0.048 13.6 7.2 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 OAJ30280.1 - 0.02 14.4 8.5 0.077 12.5 2.8 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 OAJ30280.1 - 0.25 11.1 10.2 0.89 9.4 7.2 1.8 1 1 1 2 2 2 0 Ring finger domain DZR PF12773.2 OAJ30280.1 - 1.9 8.3 8.8 5.4 6.9 6.1 1.7 1 1 0 1 1 1 0 Double zinc ribbon Acetate_kinase PF00871.12 OAJ30283.1 - 3.2e-19 68.7 0.0 2.6e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 Acetokinase family DUF469 PF04320.9 OAJ30283.1 - 0.098 13.4 0.0 0.89 10.3 0.0 2.0 1 1 1 2 2 2 0 Protein with unknown function (DUF469) Acetate_kinase PF00871.12 OAJ30284.1 - 9.1e-32 110.0 0.0 3.1e-28 98.3 0.0 2.1 2 0 0 2 2 2 2 Acetokinase family CTP_synth_N PF06418.9 OAJ30285.1 - 5.8e-116 386.4 0.0 7.9e-116 385.9 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 OAJ30285.1 - 6.9e-47 159.3 0.0 1.1e-36 126.0 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase class-I CbiA PF01656.18 OAJ30285.1 - 0.0031 16.9 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain JmjC PF02373.17 OAJ30286.1 - 1.4e-12 47.8 0.0 3.5e-12 46.5 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 OAJ30286.1 - 3.9e-10 39.6 0.0 2.9e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Cupin-like domain F-box-like PF12937.2 OAJ30286.1 - 0.00076 19.1 0.0 0.0023 17.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like Cupin_4 PF08007.7 OAJ30286.1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Nop25 PF09805.4 OAJ30287.1 - 9.5e-20 71.0 14.0 9.5e-20 71.0 9.7 2.4 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Ebola_NP PF05505.7 OAJ30287.1 - 0.46 8.4 8.6 0.54 8.2 6.0 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein Methyltransf_23 PF13489.1 OAJ30288.1 - 9.6e-11 41.6 0.0 2.3e-10 40.4 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ30288.1 - 1e-08 35.7 0.0 1.7e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ30288.1 - 1.6e-07 31.6 0.0 4.3e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ30288.1 - 1.1e-06 28.9 0.0 6e-06 26.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ30288.1 - 7.1e-06 25.6 0.0 9.4e-05 22.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ30288.1 - 2.2e-05 24.7 0.0 4.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAJ30288.1 - 0.00012 21.2 0.0 0.00031 19.8 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 OAJ30288.1 - 0.00027 20.9 0.1 0.00095 19.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ30288.1 - 0.036 13.4 0.0 0.4 10.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain MetW PF07021.7 OAJ30288.1 - 0.057 12.8 0.2 0.13 11.6 0.0 1.6 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 OAJ30288.1 - 0.065 12.3 0.0 0.18 10.8 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 OAJ30288.1 - 0.099 12.1 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 OAJ30288.1 - 0.15 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Glycos_transf_3 PF00591.16 OAJ30289.1 - 7e-68 228.7 0.0 1.2e-63 214.9 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 OAJ30289.1 - 0.00013 21.5 0.3 0.00031 20.2 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Acyl-CoA_dh_M PF02770.14 OAJ30289.1 - 0.089 12.3 0.2 0.26 10.8 0.1 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain HIT PF01230.18 OAJ30290.1 - 2.1e-23 82.6 0.0 2.7e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 OAJ30290.1 - 2.9e-07 30.7 0.0 4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding NAD_binding_2 PF03446.10 OAJ30291.1 - 4.4e-23 81.9 0.1 6.7e-23 81.3 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 OAJ30291.1 - 1.8e-08 34.5 0.0 3.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.1 OAJ30291.1 - 2.3e-08 34.1 0.1 5.1e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 OAJ30291.1 - 2.2e-05 24.7 0.1 0.00033 21.0 0.0 2.5 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Acyl_transf_3 PF01757.17 OAJ30292.1 - 2.3e-09 36.5 25.9 4.1e-09 35.7 17.9 1.5 1 1 0 1 1 1 1 Acyltransferase family Helicase_C PF00271.26 OAJ30297.1 - 4.6e-12 45.6 0.1 1.1e-11 44.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ30297.1 - 5.8e-09 35.6 0.0 1.6e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase MULE PF10551.4 OAJ30301.1 - 1.8e-16 60.0 0.0 3.8e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.10 OAJ30301.1 - 2.1e-06 27.2 0.0 4.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 MuDR family transposase SWIM PF04434.12 OAJ30301.1 - 1.5e-05 24.3 0.1 1.5e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 SWIM zinc finger Transposase_mut PF00872.13 OAJ30301.1 - 2.9e-05 22.8 0.0 4.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family Molybdopterin PF00384.17 OAJ30301.1 - 0.057 12.1 0.0 0.072 11.8 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Mic1 PF07035.7 OAJ30302.1 - 0.15 11.3 9.8 0.16 11.3 1.0 2.2 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like Gly_radical PF01228.16 OAJ30302.1 - 2.7 8.4 5.6 1.7 8.9 0.8 2.2 2 0 0 2 2 2 0 Glycine radical DUF1768 PF08719.6 OAJ30304.1 - 5.9e-20 71.5 0.0 9.3e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RBD-FIP PF09457.5 OAJ30305.1 - 0.033 13.9 0.3 0.067 12.9 0.2 1.5 1 0 0 1 1 1 0 FIP domain Ribosomal_L18ae PF01775.12 OAJ30305.1 - 0.055 13.3 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal L18ae/LX protein domain Proteasome PF00227.21 OAJ30307.1 - 5.8e-46 156.1 0.4 5.1e-43 146.5 0.1 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 OAJ30307.1 - 3.4e-14 51.8 0.1 6.3e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature AAA_33 PF13671.1 OAJ30308.1 - 3.3e-13 49.7 0.1 5.1e-12 45.8 0.0 2.6 2 1 0 2 2 1 1 AAA domain Y_phosphatase PF00102.22 OAJ30308.1 - 1.1e-06 28.1 0.0 4.6e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase RNA_ligase PF09414.5 OAJ30308.1 - 0.00023 20.9 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 RNA ligase AAA_17 PF13207.1 OAJ30308.1 - 0.00084 20.1 0.7 0.014 16.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain Y_phosphatase3 PF13350.1 OAJ30308.1 - 0.0012 19.1 1.3 0.0087 16.3 0.4 2.3 1 1 1 2 2 2 1 Tyrosine phosphatase family AAA_25 PF13481.1 OAJ30308.1 - 0.0018 17.7 0.1 0.042 13.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain DSPc PF00782.15 OAJ30308.1 - 0.0036 16.8 0.0 0.0078 15.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Zeta_toxin PF06414.7 OAJ30308.1 - 0.004 16.2 0.0 0.0092 15.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 OAJ30308.1 - 0.0063 16.8 0.1 2.5 8.3 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 OAJ30308.1 - 0.0075 16.4 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAJ30308.1 - 0.0087 15.4 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein PTPlike_phytase PF14566.1 OAJ30308.1 - 0.019 15.0 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate KTI12 PF08433.5 OAJ30308.1 - 0.039 13.1 0.3 0.77 8.9 0.2 2.2 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Plus-3 PF03126.13 OAJ30308.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Plus-3 domain AAA_5 PF07728.9 OAJ30308.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 OAJ30308.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 OAJ30308.1 - 0.2 11.5 0.0 0.71 9.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zn_clus PF00172.13 OAJ30309.1 - 1.1e-06 28.4 9.6 1.1e-06 28.4 6.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRAP_alpha PF03896.11 OAJ30309.1 - 9.7 5.0 6.2 23 3.8 4.3 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRM_6 PF14259.1 OAJ30310.1 - 4.2e-06 26.6 0.0 7.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ30310.1 - 7.2e-06 25.5 0.0 4.8e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ30310.1 - 1e-05 25.2 0.0 2.3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 OAJ30310.1 - 0.005 16.5 0.0 0.0098 15.6 0.0 1.5 1 0 0 1 1 1 1 Limkain b1 zf-CCCH_2 PF14608.1 OAJ30310.1 - 0.0061 16.5 2.4 0.019 14.9 1.7 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type FYVE PF01363.16 OAJ30310.1 - 0.007 16.2 0.2 0.007 16.2 0.2 2.1 3 0 0 3 3 3 1 FYVE zinc finger zf-CCCH PF00642.19 OAJ30310.1 - 0.018 14.6 1.2 0.018 14.6 0.8 2.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RXT2_N PF08595.6 OAJ30312.1 - 1.1e-05 25.2 0.1 0.11 12.3 0.0 2.9 2 0 0 2 2 2 2 RXT2-like, N-terminal DUF3292 PF11696.3 OAJ30312.1 - 0.25 9.1 3.0 6.9 4.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) MA3 PF02847.12 OAJ30313.1 - 1.1e-26 92.7 0.2 1.9e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.14 OAJ30313.1 - 4.5e-25 88.3 0.3 5.1e-24 84.8 0.0 2.5 2 1 0 2 2 2 1 MIF4G domain Nop14 PF04147.7 OAJ30313.1 - 2.1 6.1 19.8 0.39 8.5 9.2 2.2 2 0 0 2 2 2 0 Nop14-like family Vfa1 PF08432.5 OAJ30313.1 - 7.2 6.5 13.9 0.13 12.2 1.1 2.9 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Serglycin PF04360.7 OAJ30313.1 - 7.2 6.3 12.3 3.3 7.4 2.7 2.6 2 0 0 2 2 2 0 Serglycin CDC45 PF02724.9 OAJ30313.1 - 8.3 4.3 21.3 0.8 7.6 4.6 2.4 2 0 0 2 2 2 0 CDC45-like protein Mucin PF01456.12 OAJ30314.1 - 5 6.8 19.2 5.4 6.7 13.3 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein MFS_1 PF07690.11 OAJ30315.1 - 5e-08 32.0 21.7 5e-08 32.0 15.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily MBOAT PF03062.14 OAJ30316.1 - 6.3e-06 25.5 8.3 0.019 14.1 2.4 2.3 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 OAJ30316.1 - 9.7e-06 25.5 1.8 0.0043 17.1 0.2 2.6 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family KilA-N PF04383.8 OAJ30317.1 - 0.0011 18.5 0.0 0.0026 17.3 0.0 1.6 1 1 0 1 1 1 1 KilA-N domain TPR_11 PF13414.1 OAJ30318.1 - 1.1e-10 40.9 0.9 1.3e-09 37.5 0.7 2.2 1 1 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 OAJ30318.1 - 4.7e-09 35.4 0.2 3.1e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ30318.1 - 9.8e-06 25.1 0.3 0.18 11.8 0.4 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 OAJ30318.1 - 0.0011 18.7 0.2 0.0052 16.6 0.1 2.3 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 OAJ30318.1 - 0.0018 18.1 0.5 0.28 11.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ30318.1 - 0.02 15.4 0.4 5.3 7.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 OAJ30318.1 - 0.043 13.9 1.0 0.19 11.8 0.6 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 OAJ30318.1 - 0.07 12.9 0.0 2.1 8.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DEAD PF00270.24 OAJ30319.1 - 1.8e-43 147.9 0.0 1.3e-42 145.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ30319.1 - 9e-27 92.7 0.1 1.7e-26 91.8 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 OAJ30319.1 - 0.0063 14.9 0.0 0.011 14.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) ResIII PF04851.10 OAJ30319.1 - 0.19 11.5 0.0 0.82 9.4 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Abhydrolase_4 PF08386.5 OAJ30320.1 - 4.2e-14 52.2 0.0 1e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 OAJ30320.1 - 3.4e-11 43.1 0.1 1.3e-06 28.1 0.0 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ30320.1 - 9e-08 32.2 0.5 4.8e-07 29.8 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ30320.1 - 0.017 14.8 0.0 0.049 13.3 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family Aa_trans PF01490.13 OAJ30322.1 - 5.3e-82 275.4 32.3 6.5e-82 275.1 22.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2890 PF11081.3 OAJ30322.1 - 0.14 12.2 3.4 0.21 11.6 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nucleoplasmin PF03066.10 OAJ30322.1 - 0.55 9.7 5.4 0.9 9.0 3.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 OAJ30322.1 - 1.4 8.4 5.2 2.2 7.8 3.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.7 OAJ30322.1 - 2 8.0 7.4 2.8 7.5 5.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 OAJ30322.1 - 2 6.2 4.1 2.6 5.8 2.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 OAJ30322.1 - 4.2 5.2 5.3 6.8 4.5 3.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Retinal PF15449.1 OAJ30322.1 - 4.6 4.7 6.7 6 4.3 4.7 1.0 1 0 0 1 1 1 0 Retinal protein CAAD PF14159.1 OAJ30322.1 - 4.6 6.9 7.2 1.9 8.2 1.1 3.1 2 1 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF2076 PF09849.4 OAJ30323.1 - 8e-10 39.1 13.0 9.4e-10 38.9 9.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 OAJ30323.1 - 0.0078 16.1 4.9 0.014 15.3 3.4 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 OAJ30323.1 - 0.28 10.9 2.2 12 5.7 0.1 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like TFIIA PF03153.8 OAJ30323.1 - 5.6 6.7 7.2 6.5 6.5 5.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC14 PF08045.6 OAJ30324.1 - 7.3e-10 38.4 0.5 7.7e-05 21.9 0.2 3.0 2 1 0 2 2 2 2 Cell division control protein 14, SIN component zf-CCHC_3 PF13917.1 OAJ30324.1 - 7.8e-07 28.7 5.1 8.9e-07 28.5 2.2 2.1 2 0 0 2 2 2 1 Zinc knuckle SKG6 PF08693.5 OAJ30325.1 - 1.1e-10 40.5 1.1 1.1e-10 40.5 0.8 2.2 2 0 0 2 2 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 OAJ30325.1 - 2.4e-05 23.9 0.1 4.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF1183 PF06682.7 OAJ30325.1 - 0.0012 18.5 4.6 0.0012 18.5 3.2 4.2 4 0 0 4 4 3 1 Protein of unknown function (DUF1183) CSF-1 PF05337.6 OAJ30325.1 - 0.0023 17.3 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Macrophage colony stimulating factor-1 (CSF-1) TMEM154 PF15102.1 OAJ30325.1 - 0.005 16.5 0.2 0.012 15.3 0.2 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF912 PF06024.7 OAJ30325.1 - 0.0076 16.2 0.4 0.025 14.6 0.0 2.0 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Adeno_E3_CR2 PF02439.10 OAJ30325.1 - 0.0096 15.4 1.1 0.024 14.1 0.7 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 CENP-B_dimeris PF09026.5 OAJ30325.1 - 0.032 14.4 0.9 0.089 13.0 0.6 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BUD22 PF09073.5 OAJ30325.1 - 0.064 12.3 5.5 0.12 11.4 3.8 1.4 1 0 0 1 1 1 0 BUD22 DUF2627 PF11118.3 OAJ30325.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Rifin_STEVOR PF02009.11 OAJ30325.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family Zn_clus PF00172.13 OAJ30327.1 - 9.9e-05 22.1 15.3 0.00019 21.2 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aconitase PF00330.15 OAJ30328.1 - 4.4e-73 246.3 0.0 6.4e-48 163.3 0.0 3.0 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAJ30328.1 - 2.2e-20 73.0 0.0 4.6e-20 72.0 0.0 1.6 1 1 0 1 1 1 1 Aconitase C-terminal domain Sedlin_N PF04628.8 OAJ30329.1 - 7.5e-29 100.2 0.0 1.1e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Chorion_2 PF03964.10 OAJ30329.1 - 4.2 7.9 11.0 1.7 9.2 1.4 2.5 2 0 0 2 2 2 0 Chorion family 2 ELO PF01151.13 OAJ30330.1 - 8.2e-55 185.8 10.1 9.5e-55 185.5 7.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Dimer_Tnp_hAT PF05699.9 OAJ30332.1 - 4.9e-14 51.7 0.0 9.3e-14 50.8 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.20 OAJ30333.1 - 1.2e-40 139.3 0.0 1.8e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ30333.1 - 4.9e-20 71.6 0.0 8.3e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ30333.1 - 0.00039 19.4 0.0 0.00065 18.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ30333.1 - 0.0019 17.3 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RTC4 PF14474.1 OAJ30333.1 - 0.004 17.1 0.0 0.009 15.9 0.0 1.6 1 1 0 1 1 1 1 RTC4-like domain Pox_ser-thr_kin PF05445.6 OAJ30333.1 - 0.073 11.8 0.2 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 OAJ30333.1 - 0.12 11.7 0.2 0.37 10.1 0.2 1.8 1 1 0 1 1 1 0 RIO1 family DUF1948 PF09185.5 OAJ30334.1 - 0.065 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) Latarcin PF10279.4 OAJ30334.1 - 2.4 8.3 8.3 0.59 10.3 2.4 2.4 2 1 0 2 2 2 0 Latarcin precursor Telomere_Sde2 PF13019.1 OAJ30336.1 - 1e-37 129.3 1.0 1.7e-37 128.6 0.0 1.8 2 0 0 2 2 2 1 Telomere stability and silencing GTSE1_N PF15259.1 OAJ30336.1 - 0.0025 17.7 1.6 0.011 15.7 0.0 2.4 1 1 1 2 2 2 1 G-2 and S-phase expressed 1 DUF848 PF05852.6 OAJ30336.1 - 0.72 9.6 4.3 0.22 11.3 0.3 1.9 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF755 PF05501.6 OAJ30336.1 - 2.5 8.1 10.7 4.5 7.3 7.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF755) DUF2890 PF11081.3 OAJ30336.1 - 4.6 7.2 11.6 6 6.8 6.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) PCI PF01399.22 OAJ30337.1 - 2.6e-15 56.6 0.0 3.6e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 OAJ30337.1 - 2.6e-07 30.4 0.0 3.9e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 FeoC PF09012.5 OAJ30337.1 - 0.00011 21.7 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 FeoC like transcriptional regulator Aha1_N PF09229.6 OAJ30338.1 - 6.2e-29 100.5 0.0 8.7e-29 100.0 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 OAJ30338.1 - 8e-17 61.4 0.0 1.6e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 OAJ30338.1 - 0.0003 20.9 0.1 0.00073 19.7 0.0 1.7 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Sporozoite_P67 PF05642.6 OAJ30338.1 - 0.22 9.3 8.4 0.28 8.9 5.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MSA-2c PF12238.3 OAJ30338.1 - 0.25 10.9 7.6 0.45 10.1 5.3 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Med3 PF11593.3 OAJ30338.1 - 2 7.5 9.0 2.6 7.2 6.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Herpes_capsid PF06112.6 OAJ30338.1 - 9 6.3 14.3 21 5.1 9.9 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein VHS PF00790.14 OAJ30339.1 - 2.1e-32 111.6 0.0 4.6e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 OAJ30339.1 - 2.8e-16 58.8 0.3 4.7e-16 58.0 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ30339.1 - 1.3e-14 53.2 0.1 2.2e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ30339.1 - 2.2e-11 43.0 0.2 3.6e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 OAJ30339.1 - 0.00059 19.7 0.9 0.0031 17.4 0.2 2.5 2 1 0 2 2 2 1 GAT domain Vir_act_alpha_C PF10400.4 OAJ30339.1 - 0.014 15.7 7.2 6.5 7.1 0.0 2.8 2 0 0 2 2 2 0 Virulence activator alpha C-term Med26 PF08711.6 OAJ30339.1 - 0.11 12.0 0.8 0.71 9.4 0.0 2.2 2 0 0 2 2 2 0 TFIIS helical bundle-like domain DUF2015 PF09435.5 OAJ30340.1 - 7.8e-27 93.5 0.1 1.8e-25 89.1 0.0 2.0 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ammonium_transp PF00909.16 OAJ30341.1 - 1.1e-105 353.4 25.8 1.2e-105 353.2 17.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family MRP-S28 PF10213.4 OAJ30342.1 - 4.9e-26 91.2 0.0 2.9e-25 88.8 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit protein PHD PF00628.24 OAJ30343.1 - 5.8e-08 32.3 7.1 1.2e-07 31.2 4.9 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 OAJ30343.1 - 0.0022 17.2 7.9 0.0036 16.5 5.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.10 OAJ30343.1 - 0.25 11.0 4.6 0.46 10.2 3.2 1.4 1 0 0 1 1 1 0 CW-type Zinc Finger HEAT_EZ PF13513.1 OAJ30344.1 - 3.5e-29 100.5 10.9 1.3e-05 25.5 0.0 11.5 11 2 2 13 13 11 5 HEAT-like repeat HEAT_2 PF13646.1 OAJ30344.1 - 6e-22 77.7 12.4 2.7e-05 24.3 0.0 7.6 7 2 2 9 9 9 5 HEAT repeats HEAT PF02985.17 OAJ30344.1 - 5.8e-19 66.4 9.7 0.00027 20.7 0.1 9.3 8 0 0 8 8 8 5 HEAT repeat IBN_N PF03810.14 OAJ30344.1 - 1.7e-09 37.4 2.6 3.8e-09 36.3 0.1 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 OAJ30344.1 - 5.1e-07 30.0 0.1 0.29 11.5 0.0 5.9 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 OAJ30344.1 - 2.3e-06 27.4 0.0 5.1 7.1 0.0 6.7 8 1 1 9 9 9 1 Rix1 complex component involved in 60S ribosome maturation Adaptin_N PF01602.15 OAJ30344.1 - 3.2e-06 25.7 1.3 0.31 9.3 0.0 4.7 3 1 0 3 3 3 2 Adaptin N terminal region CAS_CSE1 PF03378.10 OAJ30344.1 - 4.9e-06 25.0 2.8 0.0082 14.4 0.0 4.6 5 0 0 5 5 5 2 CAS/CSE protein, C-terminus UME PF08064.8 OAJ30344.1 - 7.7e-06 25.8 0.1 1.8 8.5 0.0 5.9 5 1 1 6 6 6 1 UME (NUC010) domain CLASP_N PF12348.3 OAJ30344.1 - 2.9e-05 23.5 0.0 0.6 9.4 0.0 5.2 5 1 0 5 5 5 1 CLASP N terminal Cohesin_HEAT PF12765.2 OAJ30344.1 - 5.3e-05 23.0 0.2 0.84 9.6 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 OAJ30344.1 - 0.001 18.9 0.1 6.7 6.5 0.0 4.6 4 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF2237 PF09996.4 OAJ30345.1 - 9.2e-33 112.2 1.0 3e-32 110.5 0.7 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) PNRC PF15365.1 OAJ30346.1 - 9.9e-06 25.4 1.0 9.9e-06 25.4 0.7 4.5 5 2 0 5 5 5 1 Proline-rich nuclear receptor coactivator TFIIF_alpha PF05793.7 OAJ30346.1 - 0.27 9.5 16.3 0.35 9.1 11.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.4 OAJ30346.1 - 1.3 7.2 25.9 1.7 6.7 17.9 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF3533 PF12051.3 OAJ30346.1 - 1.8 7.2 3.9 2.7 6.6 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DER1 PF04511.10 OAJ30347.1 - 3.4e-28 98.4 0.8 4.5e-28 98.1 0.5 1.1 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 OAJ30347.1 - 0.052 13.5 3.2 0.083 12.9 2.2 1.4 1 0 0 1 1 1 0 Rhomboid family zf-CCCH PF00642.19 OAJ30348.1 - 6.5e-09 35.2 2.5 1.2e-08 34.4 1.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 OAJ30348.1 - 1.4e-07 31.0 5.3 2.2e-07 30.4 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ30348.1 - 1.4e-07 31.4 9.8 2.4e-07 30.6 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ30348.1 - 2.3e-06 27.3 7.0 3.6e-06 26.6 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAJ30348.1 - 4.8e-06 26.1 8.6 7.8e-06 25.5 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 OAJ30348.1 - 2.5e-05 23.8 8.5 4.3e-05 23.0 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAJ30348.1 - 7.5e-05 22.5 7.8 0.00015 21.5 5.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 OAJ30348.1 - 0.00031 20.4 5.6 0.00078 19.1 3.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 OAJ30348.1 - 0.013 14.9 3.0 0.025 14.0 2.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 OAJ30348.1 - 0.39 10.8 4.6 1.1 9.4 3.2 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger Cript PF10235.4 OAJ30348.1 - 0.4 11.0 3.4 1 9.7 2.4 1.8 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT Aldedh PF00171.17 OAJ30349.1 - 9.5e-156 518.7 0.1 1.1e-155 518.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAJ30349.1 - 0.00019 20.3 0.1 0.00029 19.7 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) V-ATPase_C PF03223.10 OAJ30350.1 - 1.2e-120 402.8 2.9 1.3e-120 402.7 2.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Virulence_fact PF13769.1 OAJ30350.1 - 0.39 10.6 2.8 1.1 9.2 0.1 2.7 2 1 1 3 3 3 0 Virulence factor S10_plectin PF03501.10 OAJ30351.1 - 3.7e-39 132.4 0.1 4.6e-39 132.1 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain HTH_45 PF14947.1 OAJ30351.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DUF4404 PF14357.1 OAJ30351.1 - 0.14 12.6 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Ribosomal_S25 PF03297.10 OAJ30352.1 - 3.6e-40 136.2 2.6 4.4e-40 135.9 1.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 OAJ30352.1 - 0.023 14.0 0.1 0.038 13.3 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.17 OAJ30352.1 - 0.04 13.6 0.2 0.077 12.7 0.1 1.5 2 0 0 2 2 2 0 MarR family CoA_trans PF01144.18 OAJ30352.1 - 0.094 11.8 0.0 0.21 10.7 0.0 1.5 1 1 1 2 2 2 0 Coenzyme A transferase MTS PF05175.9 OAJ30352.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain F_bP_aldolase PF01116.15 OAJ30353.1 - 1.5e-100 336.0 0.0 1.6e-100 335.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Dsh_C PF12316.3 OAJ30354.1 - 0.014 15.4 0.7 0.015 15.3 0.5 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF3818 PF12825.2 OAJ30355.1 - 1.4e-40 139.0 0.0 2.3e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 OAJ30355.1 - 2.2e-19 69.4 0.0 4e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 PX-associated EF1G PF00647.14 OAJ30357.1 - 2.7e-46 155.6 0.2 4.8e-46 154.8 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 OAJ30357.1 - 3.5e-14 52.7 0.0 8.4e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ30357.1 - 2.3e-11 43.5 0.0 5.2e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ30357.1 - 3e-09 36.6 0.0 7.4e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAJ30357.1 - 4e-09 36.5 0.0 8.3e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 OAJ30357.1 - 3.5e-06 27.4 0.0 1.1e-05 25.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAJ30357.1 - 3.8e-06 26.8 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.14 OAJ30357.1 - 0.46 10.9 13.4 1.2 9.5 9.3 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein RNA_pol PF00940.14 OAJ30358.1 - 3.2e-154 513.3 0.0 4.4e-154 512.8 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 OAJ30358.1 - 1e-70 238.5 0.7 1.7e-70 237.8 0.5 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Nop14 PF04147.7 OAJ30358.1 - 0.019 12.9 7.1 0.028 12.3 4.9 1.1 1 0 0 1 1 1 0 Nop14-like family RhoGEF PF00621.15 OAJ30359.1 - 3.4e-40 137.8 0.2 5.7e-40 137.1 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 OAJ30359.1 - 5.7e-33 113.5 0.0 1.1e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 OAJ30359.1 - 1.1e-20 73.4 0.2 2.9e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 CDC24 Calponin PB1 PF00564.19 OAJ30359.1 - 1.2e-09 37.6 0.1 2.4e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 OAJ30359.1 - 0.2 11.8 0.2 1.2 9.3 0.1 2.2 1 1 0 1 1 1 0 PH domain CPDase PF07823.6 OAJ30360.1 - 2.2e-29 102.3 0.0 2.4e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 OAJ30360.1 - 3.1e-05 23.7 0.1 0.0001 22.0 0.1 1.7 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily DUF3349 PF11829.3 OAJ30360.1 - 0.0069 16.7 0.0 0.018 15.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3349) zf-primase PF09329.6 OAJ30362.1 - 1.7e-10 40.3 1.0 2.9e-10 39.5 0.7 1.4 1 0 0 1 1 1 1 Primase zinc finger Glyco_hydro_25 PF01183.15 OAJ30363.1 - 3.9e-44 150.6 0.4 4.9e-44 150.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 RVT_1 PF00078.22 OAJ30365.1 - 1.7e-17 63.4 0.0 2.7e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAJ30365.1 - 1.2e-15 58.0 0.0 2.2e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 OAJ30365.1 - 0.00012 22.2 0.2 0.00027 21.1 0.1 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Clathrin PF00637.15 OAJ30366.1 - 1.5e-26 92.7 0.0 3.2e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS WD40 PF00400.27 OAJ30366.1 - 0.00015 21.5 1.8 0.0088 15.8 0.1 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat zf-rbx1 PF12678.2 OAJ30366.1 - 0.0019 18.2 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 OAJ30366.1 - 0.029 14.2 2.8 0.2 11.5 0.4 2.5 2 0 0 2 2 2 0 Ring finger domain OPT PF03169.10 OAJ30367.1 - 7.8e-135 450.7 2.4 1e-134 450.3 1.7 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1754 PF08555.5 OAJ30368.1 - 3.1e-12 46.9 5.7 3.1e-12 46.9 3.9 2.0 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) PP2C_C PF07830.8 OAJ30368.1 - 0.078 13.0 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain MelC1 PF06236.6 OAJ30368.1 - 0.084 12.8 0.3 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 CAML PF14963.1 OAJ30368.1 - 0.33 10.2 5.1 0.39 10.0 3.5 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Adaptin_binding PF10199.4 OAJ30368.1 - 0.61 10.3 4.7 0.83 9.9 3.3 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF2956 PF11169.3 OAJ30368.1 - 1.6 8.7 6.6 0.77 9.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Macoilin PF09726.4 OAJ30368.1 - 2.9 6.0 11.0 3.5 5.8 7.6 1.0 1 0 0 1 1 1 0 Transmembrane protein RasGAP_C PF03836.10 OAJ30368.1 - 4.8 6.8 9.1 4.1 7.0 1.0 2.1 2 0 0 2 2 2 0 RasGAP C-terminus NDUF_B4 PF07225.7 OAJ30369.1 - 0.012 15.4 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Nucleoside_tran PF01733.13 OAJ30370.1 - 2.4e-20 72.9 10.3 2.9e-18 66.1 2.7 3.8 2 1 1 3 3 3 2 Nucleoside transporter Ribosomal_L21p PF00829.16 OAJ30371.1 - 2.6e-08 33.8 1.4 1e-06 28.7 1.5 2.1 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein zf-CCHC_6 PF15288.1 OAJ30372.1 - 0.0032 17.0 0.4 0.0083 15.7 0.3 1.7 1 0 0 1 1 1 1 Zinc knuckle Pkinase PF00069.20 OAJ30373.1 - 2.5e-23 82.5 0.0 3.4e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ30373.1 - 7.3e-14 51.4 0.0 1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ30373.1 - 0.00027 20.0 0.0 0.00036 19.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Glyco_hydro_63 PF03200.11 OAJ30375.1 - 8.7e-231 768.0 0.0 7.7e-230 764.9 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 OAJ30375.1 - 3.6e-05 22.5 0.0 5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Trehalase DUF4432 PF14486.1 OAJ30376.1 - 0.071 11.6 0.0 0.097 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) F-box-like PF12937.2 OAJ30376.1 - 0.084 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like ARID PF01388.16 OAJ30377.1 - 7.9e-15 54.4 0.0 7.9e-15 54.4 0.0 3.9 4 0 0 4 4 4 1 ARID/BRIGHT DNA binding domain DUF2890 PF11081.3 OAJ30378.1 - 0.023 14.7 4.4 0.027 14.5 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Utp14 PF04615.8 OAJ30378.1 - 0.058 11.5 2.0 0.057 11.5 1.4 1.0 1 0 0 1 1 1 0 Utp14 protein FAM176 PF14851.1 OAJ30378.1 - 0.07 12.8 1.4 0.077 12.6 1.0 1.2 1 0 0 1 1 1 0 FAM176 family DUF4637 PF15470.1 OAJ30378.1 - 0.15 11.6 5.5 0.17 11.4 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Sporozoite_P67 PF05642.6 OAJ30378.1 - 0.16 9.7 2.9 0.15 9.9 2.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 OAJ30378.1 - 0.2 10.0 8.0 0.23 9.9 5.6 1.0 1 0 0 1 1 1 0 Daxx Family PBP1_TM PF14812.1 OAJ30378.1 - 0.41 10.9 10.7 0.56 10.5 7.4 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 OAJ30378.1 - 0.45 10.3 6.5 0.55 10.0 4.5 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.7 OAJ30378.1 - 0.7 7.7 6.7 0.6 7.9 4.6 1.0 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.5 OAJ30378.1 - 1 9.6 13.1 1.5 9.0 9.1 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.9 OAJ30378.1 - 1.1 7.2 4.3 0.94 7.4 3.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 OAJ30378.1 - 1.8 7.2 11.9 2.1 6.9 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.7 OAJ30378.1 - 4.7 6.2 9.3 5.2 6.1 6.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 OAJ30378.1 - 5.6 6.5 10.4 7.1 6.1 7.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.8 OAJ30378.1 - 5.8 4.5 14.7 6.4 4.4 10.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nucleoplasmin PF03066.10 OAJ30378.1 - 7.7 6.0 15.9 10 5.5 11.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin WD40 PF00400.27 OAJ30379.1 - 8.8e-17 60.2 11.7 1.6e-05 24.6 0.3 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Rax2 PF12768.2 OAJ30379.1 - 0.005 16.0 0.1 0.012 14.8 0.0 1.7 2 0 0 2 2 2 1 Cortical protein marker for cell polarity DPPIV_N PF00930.16 OAJ30379.1 - 0.0067 15.0 0.9 0.19 10.3 0.5 2.5 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1748 PF08520.5 OAJ30380.1 - 1.9e-27 94.6 0.0 2.1e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Abhydrolase_3 PF07859.8 OAJ30381.1 - 1.1e-24 87.2 0.0 1.3e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ30381.1 - 0.00092 18.9 0.1 0.0017 18.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 OAJ30381.1 - 0.0018 17.6 0.1 0.003 16.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 OAJ30381.1 - 0.023 14.5 0.9 0.38 10.6 0.7 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.13 OAJ30381.1 - 0.023 13.9 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Glyco_hydro_114 PF03537.8 OAJ30381.1 - 0.049 13.4 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 Glycoprotein_G PF00802.14 OAJ30382.1 - 0.0025 17.0 15.1 0.0041 16.3 10.5 1.3 1 0 0 1 1 1 1 Pneumovirus attachment glycoprotein G QueF_N PF14819.1 OAJ30382.1 - 0.11 12.6 1.6 9.3 6.3 0.0 3.0 2 1 1 3 3 3 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term DUF4106 PF13388.1 OAJ30382.1 - 1 8.2 3.9 2 7.2 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) PRKCSH-like PF12999.2 OAJ30383.1 - 7.7e-43 146.0 6.5 7.7e-43 146.0 4.5 2.4 2 1 1 3 3 3 1 Glucosidase II beta subunit-like Ribosomal_S30 PF04758.9 OAJ30383.1 - 3e-26 90.9 6.7 8e-26 89.5 4.6 1.8 1 0 0 1 1 1 1 Ribosomal protein S30 PRKCSH_1 PF13015.1 OAJ30383.1 - 2.1e-23 82.5 0.1 4.8e-23 81.3 0.1 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 OAJ30383.1 - 1.3e-08 35.5 1.5 1.3e-08 35.5 1.1 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF2968 PF11180.3 OAJ30383.1 - 0.002 17.5 6.7 0.0091 15.3 4.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2968) IncA PF04156.9 OAJ30383.1 - 0.0091 15.6 3.3 0.14 11.7 1.1 2.4 2 0 0 2 2 2 1 IncA protein DUF3584 PF12128.3 OAJ30383.1 - 0.033 11.5 5.8 0.0051 14.2 1.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) bZIP_1 PF00170.16 OAJ30383.1 - 0.044 13.7 9.9 0.75 9.7 0.7 2.7 2 0 0 2 2 2 0 bZIP transcription factor CDC37_N PF03234.9 OAJ30383.1 - 0.076 13.3 4.4 0.27 11.5 1.1 2.4 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Seryl_tRNA_N PF02403.17 OAJ30383.1 - 7 6.7 13.1 13 5.8 4.6 2.9 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TATR PF03430.8 OAJ30384.1 - 1.1 7.8 2.6 1.7 7.2 1.8 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Sad1_UNC PF07738.8 OAJ30385.1 - 7.1e-08 32.3 0.1 0.014 15.1 0.1 2.9 2 1 0 2 2 2 2 Sad1 / UNC-like C-terminal An_peroxidase PF03098.10 OAJ30386.1 - 3.1e-77 260.1 0.0 2.9e-57 194.2 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 OAJ30386.1 - 1.1e-12 47.1 0.0 2e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF2235 PF09994.4 OAJ30387.1 - 1.2e-77 261.0 0.0 1.9e-77 260.3 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 OAJ30387.1 - 0.0045 16.7 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.6 OAJ30387.1 - 0.038 13.6 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PX PF00787.19 OAJ30388.1 - 1e-16 60.6 0.1 5.2e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.4 OAJ30388.1 - 3.7e-07 29.6 0.5 9.9e-07 28.2 0.4 1.6 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.23 OAJ30388.1 - 3.1e-05 23.2 0.0 7.2e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PXA PF02194.10 OAJ30388.1 - 0.8 9.2 1.2 1.4 8.4 0.9 1.3 1 0 0 1 1 1 0 PXA domain Dimer_Tnp_hAT PF05699.9 OAJ30389.1 - 1.5e-23 82.2 0.1 4.9e-23 80.5 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 OAJ30389.1 - 1.2e-06 28.1 2.5 2.5e-06 27.1 1.7 1.6 1 0 0 1 1 1 1 BED zinc finger DUF59 PF01883.14 OAJ30389.1 - 0.026 14.5 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF59 SF3b10 PF07189.6 OAJ30391.1 - 4.8e-29 100.0 0.0 5.5e-29 99.8 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MULE PF10551.4 OAJ30392.1 - 2e-07 31.0 0.1 5.8e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.12 OAJ30392.1 - 0.0018 17.7 0.1 0.0052 16.2 0.1 1.8 1 0 0 1 1 1 1 SWIM zinc finger Abhydrolase_5 PF12695.2 OAJ30393.1 - 0.00025 20.8 0.0 0.00065 19.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ30393.1 - 0.0044 16.2 0.0 0.0099 15.1 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Cullin PF00888.17 OAJ30394.1 - 1.9e-176 588.0 3.4 2.6e-176 587.6 2.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 OAJ30394.1 - 1.2e-27 95.4 1.4 2.7e-27 94.3 0.9 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_27 PF13463.1 OAJ30394.1 - 0.0024 18.1 0.1 6.9 7.0 0.0 3.3 4 0 0 4 4 4 2 Winged helix DNA-binding domain Penicillinase_R PF03965.11 OAJ30394.1 - 0.023 14.8 2.1 18 5.4 0.0 3.9 4 0 0 4 4 4 0 Penicillinase repressor Ubie_methyltran PF01209.13 OAJ30395.1 - 8.1e-71 237.8 0.0 1.3e-37 129.2 0.0 2.2 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 OAJ30395.1 - 5.3e-11 42.8 0.0 6.8e-10 39.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ30395.1 - 2e-10 41.0 0.0 4.1e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ30395.1 - 1.8e-09 37.3 0.0 2.2e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ30395.1 - 7.8e-07 28.9 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ30395.1 - 1e-06 29.3 0.0 2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ30395.1 - 1.7e-06 28.0 0.0 4.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ30395.1 - 1.4e-05 25.3 0.0 2.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 OAJ30395.1 - 0.008 15.8 0.0 0.026 14.1 0.0 1.7 2 0 0 2 2 2 1 Hypothetical methyltransferase MTS PF05175.9 OAJ30395.1 - 0.059 12.7 0.0 0.44 9.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Glyco_transf_90 PF05686.7 OAJ30395.1 - 0.12 10.9 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 90 DUF952 PF06108.7 OAJ30396.1 - 1.4e-10 40.9 0.0 2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) GPI-anchored PF10342.4 OAJ30397.1 - 5.8e-10 39.5 0.1 5.8e-10 39.5 0.1 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mob1_phocein PF03637.12 OAJ30398.1 - 2.3e-55 186.9 0.7 2.9e-55 186.6 0.5 1.1 1 0 0 1 1 1 1 Mob1/phocein family Glycos_transf_4 PF00953.16 OAJ30399.1 - 4.7e-32 111.0 7.2 9.6e-32 109.9 5.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 4 CAP59_mtransfer PF11735.3 OAJ30401.1 - 1.2e-66 224.4 0.0 1.3e-63 214.4 0.0 2.2 2 0 0 2 2 2 2 Cryptococcal mannosyltransferase 1 BUD22 PF09073.5 OAJ30401.1 - 0.71 8.8 9.7 1.3 8.0 6.7 1.3 1 0 0 1 1 1 0 BUD22 Dicty_REP PF05086.7 OAJ30401.1 - 2.1 5.9 5.6 2.9 5.5 3.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Fasciclin PF02469.17 OAJ30402.1 - 5e-28 97.6 8.1 6.3e-21 74.7 2.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Ub-RnfH PF03658.9 OAJ30402.1 - 0.054 13.3 0.1 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RnfH family Ubiquitin DnaJ PF00226.26 OAJ30403.1 - 2.2e-09 36.8 0.5 6.7e-09 35.3 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain Peptidase_M3 PF01432.15 OAJ30404.1 - 6.4e-129 430.9 0.0 8.5e-129 430.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Ras PF00071.17 OAJ30405.1 - 3.1e-54 182.7 0.0 3.6e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ30405.1 - 1.1e-14 54.9 0.0 1.5e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ30405.1 - 1.2e-07 31.0 0.0 2.4e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ30405.1 - 0.0094 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 OAJ30405.1 - 0.029 13.8 0.0 1.7 8.0 0.0 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Iso_dh PF00180.15 OAJ30408.1 - 2.9e-70 236.9 0.0 3.7e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glycos_transf_2 PF00535.21 OAJ30410.1 - 2.8e-20 72.6 0.0 1.5e-19 70.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 OAJ30410.1 - 2.9e-07 30.5 0.2 0.00048 20.0 0.0 2.8 3 0 0 3 3 3 2 Glycosyltransferase like family 2 CDK2AP PF09806.4 OAJ30410.1 - 0.21 11.7 2.4 1.6 8.9 1.3 2.4 2 1 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein SHR3_chaperone PF08229.6 OAJ30413.1 - 4.8e-23 81.1 0.0 1e-22 80.0 0.0 1.5 1 1 0 1 1 1 1 ER membrane protein SH3 Med21 PF11221.3 OAJ30413.1 - 0.095 12.6 2.9 0.16 11.9 2.0 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex SecG PF03840.9 OAJ30413.1 - 3.4 7.4 8.5 0.12 12.0 0.4 2.4 2 0 0 2 2 2 0 Preprotein translocase SecG subunit Mss4 PF04421.8 OAJ30414.1 - 1.1e-10 41.1 1.3 0.00031 20.5 0.0 2.7 2 0 0 2 2 2 2 Mss4 protein Acetyltransf_1 PF00583.19 OAJ30414.1 - 0.00048 20.0 1.2 0.0019 18.1 0.0 2.6 4 0 0 4 4 4 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ30414.1 - 0.074 13.2 0.0 3.1 8.0 0.0 2.8 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain DNA_pol_B_thumb PF14791.1 OAJ30415.1 - 2.6e-20 71.8 0.0 6.9e-20 70.5 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 OAJ30415.1 - 7.9e-20 70.9 0.1 6.3e-19 68.0 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase beta palm HHH_8 PF14716.1 OAJ30415.1 - 4.4e-07 29.9 0.1 1.2e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 OAJ30415.1 - 5.7e-07 28.9 0.0 1.8e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 OAJ30415.1 - 1.5e-05 25.0 0.1 0.00065 19.8 0.0 2.9 3 0 0 3 3 3 1 Helix-hairpin-helix domain XPG_I PF00867.13 OAJ30416.1 - 1.1e-26 92.6 0.0 2.4e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 OAJ30416.1 - 3.3e-25 88.2 0.0 8e-25 87.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 OAJ30416.1 - 0.00059 19.3 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 OAJ30416.1 - 0.042 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Hemerythrin PF01814.18 OAJ30417.1 - 1.3e-08 35.1 9.6 1.4e-07 31.7 5.7 1.8 2 1 1 3 3 3 2 Hemerythrin HHE cation binding domain DDE_Tnp_IS1595 PF12762.2 OAJ30417.1 - 0.06 13.1 0.5 0.18 11.6 0.3 1.7 2 0 0 2 2 2 0 ISXO2-like transposase domain DUF2031 PF09592.5 OAJ30417.1 - 0.22 10.6 3.5 0.12 11.5 0.8 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2031) Ndc80_HEC PF03801.8 OAJ30418.1 - 6.8e-36 123.1 0.4 1.1e-35 122.3 0.0 1.5 2 0 0 2 2 2 1 HEC/Ndc80p family Exo_endo_phos PF03372.18 OAJ30419.1 - 4.4e-28 98.8 0.1 8.6e-28 97.9 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF605 PF04652.11 OAJ30419.1 - 6.4 6.0 21.5 12 5.2 14.9 1.3 1 0 0 1 1 1 0 Vta1 like LSM PF01423.17 OAJ30421.1 - 3.4e-16 58.5 0.9 4.3e-16 58.2 0.7 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 OAJ30421.1 - 0.034 14.0 0.1 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_C PF02237.12 OAJ30421.1 - 0.099 12.3 0.9 0.18 11.5 0.7 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain SRP9-21 PF05486.7 OAJ30422.1 - 7.8e-17 60.7 0.5 9.9e-17 60.4 0.3 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) AAA_27 PF13514.1 OAJ30422.1 - 0.0075 14.0 1.2 0.0086 13.8 0.8 1.0 1 0 0 1 1 1 1 AAA domain CN_hydrolase PF00795.17 OAJ30423.1 - 2.1e-30 105.4 0.0 3e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RRM_1 PF00076.17 OAJ30424.1 - 2.7e-29 100.5 0.1 7.6e-18 63.9 0.2 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ30424.1 - 1.4e-20 73.0 0.1 1.8e-12 47.0 0.1 3.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ30424.1 - 1.8e-12 46.8 0.0 2.8e-07 30.2 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 OAJ30424.1 - 2.6e-10 39.7 0.1 0.0006 19.4 0.0 2.8 2 0 0 2 2 2 2 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 OAJ30424.1 - 0.017 14.8 0.4 9.7 6.0 0.1 2.9 3 0 0 3 3 3 0 Limkain b1 Nup35_RRM PF05172.8 OAJ30424.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Peptidase_S55 PF05580.7 OAJ30424.1 - 0.15 11.4 0.0 0.64 9.4 0.0 2.0 2 0 0 2 2 2 0 SpoIVB peptidase S55 TMPIT PF07851.8 OAJ30425.1 - 1.2 8.0 2.8 3.3 6.6 1.9 1.7 1 0 0 1 1 1 0 TMPIT-like protein UBX PF00789.15 OAJ30426.1 - 1.2e-10 41.2 0.0 1.9e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 UBX domain UDG PF03167.14 OAJ30427.1 - 6.1e-21 74.4 0.0 1.4e-11 44.1 0.0 2.3 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily Xan_ur_permease PF00860.15 OAJ30428.1 - 5.6e-27 94.2 27.7 1.8e-25 89.2 19.2 2.2 1 1 0 1 1 1 1 Permease family Sulfate_transp PF00916.15 OAJ30428.1 - 0.00076 18.5 5.2 0.0013 17.8 3.0 1.8 1 1 0 1 1 1 1 Sulfate transporter family Zn_clus PF00172.13 OAJ30429.1 - 2e-06 27.5 6.8 3.7e-06 26.7 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.4 OAJ30429.1 - 0.12 12.1 1.3 0.23 11.2 0.9 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Arch_ATPase PF01637.13 OAJ30430.1 - 8.4e-11 42.0 0.0 2.3e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase AAA_29 PF13555.1 OAJ30430.1 - 0.36 10.3 1.4 0.98 8.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ30430.1 - 0.69 9.8 5.4 3.4 7.5 0.3 3.6 2 2 1 3 3 3 0 AAA ATPase domain RasGAP_C PF03836.10 OAJ30431.1 - 7.4e-44 148.8 5.9 7.4e-44 148.8 4.1 2.3 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 OAJ30431.1 - 3e-40 137.9 4.6 3.7e-40 137.7 0.0 3.0 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 OAJ30431.1 - 1.3e-22 77.2 28.4 0.02 14.4 0.0 10.0 9 0 0 9 9 9 8 IQ calmodulin-binding motif CH PF00307.26 OAJ30431.1 - 3.6e-12 46.2 0.0 8.8e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain PAZ_siRNAbind PF12212.3 OAJ30431.1 - 0.11 12.1 0.3 17 5.0 0.0 2.6 2 0 0 2 2 2 0 Piwi/Argonaute/Zwille siRNA-binding domain adh_short PF00106.20 OAJ30432.1 - 8.5e-11 42.0 0.0 1.3e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ30432.1 - 0.04 13.5 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.1 OAJ30432.1 - 0.052 13.3 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 OAJ30432.1 - 0.069 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PK PF00224.16 OAJ30433.1 - 4.6e-159 528.6 1.0 5.6e-159 528.3 0.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 OAJ30433.1 - 4.4e-32 110.0 0.0 1.2e-31 108.7 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 OAJ30433.1 - 3.8e-05 22.6 1.1 0.00017 20.5 0.8 2.1 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 OAJ30433.1 - 0.00012 21.1 0.1 0.0022 16.9 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Cellulase PF00150.13 OAJ30433.1 - 0.069 12.3 0.0 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Peptidase_U32 PF01136.14 OAJ30433.1 - 0.081 11.8 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family U32 HVSL PF09749.4 OAJ30435.1 - 2.6e-35 121.5 0.0 3.4e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein SR-25 PF10500.4 OAJ30435.1 - 1.5 8.1 6.2 2.7 7.4 4.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein tRNA-synt_1 PF00133.17 OAJ30436.1 - 3e-43 147.7 0.0 1.2e-34 119.3 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 OAJ30436.1 - 2.1e-15 56.3 0.0 5.4e-09 35.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 OAJ30436.1 - 7.7e-11 41.9 0.0 1.9e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 OAJ30436.1 - 2.4e-07 30.1 0.0 4.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 OAJ30436.1 - 0.011 15.0 0.2 0.21 10.8 0.0 2.4 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 adh_short_C2 PF13561.1 OAJ30437.1 - 4.4e-29 101.9 0.0 5e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ30437.1 - 6e-17 62.0 0.3 7.4e-17 61.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ30437.1 - 4.8e-07 29.6 0.2 7e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAJ30437.1 - 0.021 14.8 0.1 0.041 13.8 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding Shikimate_DH PF01488.15 OAJ30437.1 - 0.023 14.7 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 OAJ30437.1 - 0.027 13.5 0.2 0.067 12.2 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 OAJ30437.1 - 0.08 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Eno-Rase_NADH_b PF12242.3 OAJ30437.1 - 0.094 12.5 0.4 0.21 11.4 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 OAJ30437.1 - 0.1 12.0 0.2 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NYN PF01936.13 OAJ30438.1 - 1.6e-22 80.3 0.0 4.3e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 NYN domain DNA_pol_phi PF04931.8 OAJ30438.1 - 4.5 4.9 8.3 6.5 4.3 5.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi RabGAP-TBC PF00566.13 OAJ30439.1 - 1.1e-28 100.2 6.8 2.4e-28 99.0 0.0 3.3 4 0 0 4 4 4 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 OAJ30439.1 - 1.5e-05 24.3 0.0 8.4e-05 21.9 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3548) PIG-P PF08510.7 OAJ30440.1 - 5.3e-24 84.2 4.8 9.2e-24 83.4 2.9 1.5 1 1 1 2 2 2 1 PIG-P DUF1348 PF07080.6 OAJ30442.1 - 5e-49 165.7 4.7 6.1e-49 165.5 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 OAJ30442.1 - 4.4e-07 30.2 0.0 6.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 OAJ30442.1 - 0.009 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.1 OAJ30442.1 - 0.018 14.9 0.1 0.039 13.8 0.0 1.5 2 0 0 2 2 2 0 SnoaL-like domain SnoaL PF07366.7 OAJ30442.1 - 0.031 13.8 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Oxysterol_BP PF01237.13 OAJ30443.1 - 1.8e-83 279.9 0.0 2.3e-83 279.6 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein LMWPc PF01451.16 OAJ30444.1 - 6e-34 117.3 0.0 6.8e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase BNR PF02012.15 OAJ30445.1 - 2.2 8.4 6.1 1.2e+02 3.1 0.0 4.8 5 0 0 5 5 5 0 BNR/Asp-box repeat Prenyltransf PF01255.14 OAJ30446.1 - 4.6e-75 251.5 0.0 5.8e-75 251.2 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Rer1 PF03248.8 OAJ30446.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Rer1 family Sgf11 PF08209.6 OAJ30449.1 - 1.5e-13 49.7 3.6 8.1e-13 47.4 0.4 2.4 2 0 0 2 2 2 2 Sgf11 (transcriptional regulation protein) Peptidase_M13_N PF05649.8 OAJ30451.1 - 1.4e-06 27.6 0.0 1.7e-06 27.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 DUF605 PF04652.11 OAJ30452.1 - 0.11 11.9 7.6 0.13 11.6 5.2 1.0 1 0 0 1 1 1 0 Vta1 like Ank_2 PF12796.2 OAJ30453.1 - 1.8e-14 53.8 0.0 2e-12 47.2 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 OAJ30453.1 - 4.6e-12 45.7 0.2 0.00067 19.8 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAJ30453.1 - 1.1e-11 44.9 0.0 3.6e-06 27.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 OAJ30453.1 - 2.8e-08 33.1 0.0 0.18 11.6 0.0 4.4 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 OAJ30453.1 - 9.8e-07 28.4 0.3 0.012 15.7 0.0 3.9 4 1 0 4 4 3 1 Ankyrin repeat SGT1 PF07093.6 OAJ30453.1 - 0.02 13.3 2.0 0.021 13.2 1.4 1.2 1 0 0 1 1 1 0 SGT1 protein Nop14 PF04147.7 OAJ30453.1 - 0.039 11.8 11.2 0.042 11.7 7.7 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 OAJ30453.1 - 0.049 12.7 14.3 0.052 12.6 9.2 1.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Nucleoplasmin PF03066.10 OAJ30453.1 - 0.21 11.1 14.4 0.29 10.6 10.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 OAJ30453.1 - 0.46 9.1 18.8 0.53 8.9 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 OAJ30453.1 - 0.49 9.5 14.8 0.62 9.2 10.3 1.1 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 OAJ30453.1 - 0.57 8.6 15.4 0.67 8.3 10.7 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 OAJ30453.1 - 0.7 9.1 12.1 0.84 8.8 8.4 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.8 OAJ30453.1 - 1.7 8.1 13.7 2.4 7.7 9.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Paf1 PF03985.8 OAJ30453.1 - 2.7 6.6 8.6 3.7 6.1 5.9 1.1 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.9 OAJ30453.1 - 4.9 5.0 9.8 5.7 4.8 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 OAJ30453.1 - 5 7.1 7.2 7.2 6.6 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) RXT2_N PF08595.6 OAJ30453.1 - 8.6 6.1 10.5 13 5.5 7.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NMT PF01233.14 OAJ30454.1 - 2.5e-75 251.5 0.0 4.1e-75 250.8 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 OAJ30454.1 - 1.7e-62 210.1 0.0 6.5e-62 208.2 0.0 1.9 2 1 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 OAJ30454.1 - 0.0027 17.5 0.0 0.0084 15.9 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAJ30454.1 - 0.059 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAJ30454.1 - 0.099 12.6 0.1 2.6 8.1 0.0 2.8 2 1 1 3 3 3 0 Acetyltransferase (GNAT) family HC2 PF07382.6 OAJ30455.1 - 3e-13 50.0 47.9 3e-13 50.0 33.2 7.1 2 2 5 7 7 7 2 Histone H1-like nucleoprotein HC2 PAZ PF02170.17 OAJ30456.1 - 3.8e-08 32.7 0.0 5.6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 PAZ domain DUF1797 PF08796.5 OAJ30456.1 - 0.031 14.1 0.1 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) DUF1517 PF07466.6 OAJ30456.1 - 0.091 11.7 1.7 0.12 11.3 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF2763 PF10961.3 OAJ30456.1 - 9.1 6.7 13.5 16 5.9 9.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) CTNNBL PF08216.6 OAJ30457.1 - 2e-27 94.9 1.6 4.7e-27 93.7 0.1 2.3 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 OAJ30457.1 - 0.021 15.0 2.8 0.14 12.4 0.1 3.7 5 0 0 5 5 5 0 HEAT repeats Pox_E10 PF04805.7 OAJ30457.1 - 0.18 11.3 0.0 0.54 9.8 0.0 1.7 1 0 0 1 1 1 0 E10-like protein conserved region Arm PF00514.18 OAJ30457.1 - 0.26 11.1 2.3 1.5 8.8 0.1 2.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat AT_hook PF02178.14 OAJ30458.1 - 0.0067 15.9 21.0 0.063 12.9 3.1 3.1 2 0 0 2 2 2 2 AT hook motif DUF448 PF04296.8 OAJ30458.1 - 0.036 13.7 0.0 0.13 11.9 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF448) MFS_1 PF07690.11 OAJ30459.1 - 3.6e-28 98.3 27.9 1.3e-27 96.4 19.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 OAJ30459.1 - 3.9 7.6 13.5 3 7.9 1.1 3.6 3 1 2 5 5 5 0 NfeD-like C-terminal, partner-binding RRM_1 PF00076.17 OAJ30461.1 - 4e-19 68.0 0.1 6.1e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ30461.1 - 1.5e-10 40.9 0.0 2.1e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ30461.1 - 5.7e-05 22.8 0.0 8.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.4 OAJ30462.1 - 7.7 5.9 23.8 9.1 5.6 1.3 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein WD40 PF00400.27 OAJ30463.1 - 2.5e-13 49.3 11.7 7.5e-07 28.8 0.2 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 OAJ30463.1 - 2.1e-05 22.8 0.1 0.00031 19.0 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 tRNA_Me_trans PF03054.11 OAJ30464.1 - 1.1e-93 313.6 0.0 3.6e-81 272.4 0.0 2.9 2 1 0 2 2 2 2 tRNA methyl transferase NAD_synthase PF02540.12 OAJ30464.1 - 4e-06 25.8 0.0 0.0009 18.2 0.0 2.2 2 0 0 2 2 2 2 NAD synthase ThiI PF02568.9 OAJ30464.1 - 0.00077 18.9 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 OAJ30464.1 - 0.045 13.2 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Kelch_4 PF13418.1 OAJ30467.1 - 2.8e-42 142.2 13.1 2e-07 30.6 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 OAJ30467.1 - 1.4e-30 104.7 26.2 7.9e-08 32.2 0.3 7.8 8 1 0 8 8 8 5 Galactose oxidase, central domain Kelch_1 PF01344.20 OAJ30467.1 - 1.8e-29 101.0 4.2 8.9e-06 25.1 0.0 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 OAJ30467.1 - 5.5e-25 86.8 9.4 9.8e-07 28.6 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 OAJ30467.1 - 4.4e-22 76.9 9.2 4.4e-05 23.0 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 OAJ30467.1 - 1.4e-21 75.6 9.6 0.00029 20.8 0.0 6.2 5 1 1 6 6 6 5 Kelch motif PQQ_3 PF13570.1 OAJ30467.1 - 0.51 10.6 7.0 2.5 8.5 0.1 4.7 5 0 0 5 5 5 0 PQQ-like domain Adaptin_N PF01602.15 OAJ30468.1 - 8.9e-57 192.5 0.0 2.1e-33 115.4 0.0 3.2 3 0 0 3 3 3 3 Adaptin N terminal region HEAT_2 PF13646.1 OAJ30468.1 - 2.3e-08 34.2 10.8 3.1e-06 27.3 3.1 5.7 4 2 2 6 6 6 2 HEAT repeats HEAT PF02985.17 OAJ30468.1 - 0.00011 21.9 7.4 2.6 8.3 0.0 5.5 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 OAJ30468.1 - 0.0076 16.7 1.4 0.0076 16.7 1.0 6.2 7 1 1 8 8 8 2 HEAT-like repeat Myc_N PF01056.13 OAJ30468.1 - 3.1 6.8 23.5 0.012 14.7 1.8 3.8 3 0 0 3 3 3 0 Myc amino-terminal region Chs3p PF12271.3 OAJ30470.1 - 2.1e-117 391.3 17.7 2.4e-117 391.0 12.3 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF605 PF04652.11 OAJ30472.1 - 4.4 6.6 28.7 6 6.1 19.9 1.1 1 0 0 1 1 1 0 Vta1 like RRM_6 PF14259.1 OAJ30473.1 - 4.2e-10 39.4 0.0 5.7e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ30473.1 - 2e-08 33.9 0.0 2.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ30473.1 - 2.2e-08 33.5 0.0 2.8e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NapD PF03927.8 OAJ30473.1 - 0.0052 16.5 0.0 0.0078 16.0 0.0 1.2 1 0 0 1 1 1 1 NapD protein RRM_3 PF08777.6 OAJ30473.1 - 0.033 14.0 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.1 OAJ30473.1 - 0.047 13.4 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF605 PF04652.11 OAJ30473.1 - 1.5 8.1 9.6 1.4 8.2 6.7 1.1 1 0 0 1 1 1 0 Vta1 like Phage_integrase PF00589.17 OAJ30474.1 - 4.3e-06 26.4 0.0 4.8e-06 26.3 0.0 1.3 1 1 0 1 1 1 1 Phage integrase family HIT PF01230.18 OAJ30475.1 - 4.8e-09 36.6 0.0 7.2e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 OAJ30475.1 - 0.0029 17.8 0.0 0.0038 17.4 0.0 1.3 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 OAJ30475.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.8 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Zn_clus PF00172.13 OAJ30476.1 - 1.3e-07 31.3 9.6 2.4e-07 30.5 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L19e PF01280.15 OAJ30476.1 - 0.15 11.8 3.3 5 6.8 0.3 2.7 2 0 0 2 2 2 0 Ribosomal protein L19e Ribosomal_60s PF00428.14 OAJ30476.1 - 5.1 7.5 26.3 1.2 9.5 2.7 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein Methyltransf_16 PF10294.4 OAJ30477.1 - 7.7e-41 139.4 0.0 1.1e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 OAJ30477.1 - 0.00076 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 OAJ30477.1 - 0.001 19.6 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ30477.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Dioxygenase_C PF00775.16 OAJ30478.1 - 1e-07 31.3 0.2 3.2e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Dioxygenase DNA_pol_phi PF04931.8 OAJ30479.1 - 1.9e-12 45.8 41.8 2.9e-12 45.2 29.0 1.2 1 0 0 1 1 1 1 DNA polymerase phi Autophagy_act_C PF03987.10 OAJ30481.1 - 7.7e-11 42.0 4.0 6.2e-10 39.1 2.8 2.3 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RabGAP-TBC PF00566.13 OAJ30482.1 - 4e-50 170.2 0.0 5.4e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_1 PF00018.23 OAJ30482.1 - 0.0072 15.6 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ30482.1 - 0.0086 15.5 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain RRM_1 PF00076.17 OAJ30483.1 - 3.7e-12 45.7 0.0 5e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ30483.1 - 2.5e-08 33.7 0.0 3.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ30483.1 - 0.00014 21.6 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAJ30483.1 - 0.00024 20.7 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif AbiH PF14253.1 OAJ30484.1 - 0.065 12.8 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH SET PF00856.23 OAJ30486.1 - 2.6e-23 83.0 3.3 1.7e-22 80.4 0.2 2.9 2 1 0 2 2 2 1 SET domain SRI PF08236.6 OAJ30486.1 - 1.1e-15 57.3 3.7 1.1e-15 57.3 2.6 2.2 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 OAJ30486.1 - 0.0048 16.3 0.1 0.02 14.3 0.0 2.1 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Abhydrolase_6 PF12697.2 OAJ30487.1 - 0.00049 20.0 0.0 0.0018 18.1 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ30487.1 - 0.0042 16.8 0.0 0.012 15.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAJ30487.1 - 0.04 13.5 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Amino_oxidase PF01593.19 OAJ30488.1 - 2.3e-45 155.5 2.2 3.5e-44 151.6 1.6 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAJ30488.1 - 3.9e-12 46.0 1.3 1.1e-11 44.5 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ30488.1 - 2.9e-07 29.7 0.3 0.00022 20.2 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 OAJ30488.1 - 6.3e-07 28.2 0.7 0.00048 18.7 0.3 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 OAJ30488.1 - 6e-06 25.3 1.0 1e-05 24.6 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 OAJ30488.1 - 6.5e-05 23.2 0.3 0.00043 20.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAJ30488.1 - 7.4e-05 22.9 0.2 0.042 13.9 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ30488.1 - 0.00015 21.6 0.1 0.00048 20.0 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAJ30488.1 - 0.00019 20.5 0.2 0.00035 19.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 OAJ30488.1 - 0.0004 19.5 1.8 0.00062 18.9 0.5 1.8 2 1 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 OAJ30488.1 - 0.0011 18.7 0.6 0.42 10.3 0.1 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 OAJ30488.1 - 0.0022 17.0 0.1 1.3 7.8 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.2 OAJ30488.1 - 0.026 13.6 2.3 0.04 13.0 1.6 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 OAJ30488.1 - 0.063 12.1 1.4 0.23 10.2 0.5 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Glyco_hydro_cc PF11790.3 OAJ30489.1 - 7.5e-55 185.9 2.1 9.8e-55 185.5 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.8 OAJ30489.1 - 0.09 11.5 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 RVT_2 PF07727.9 OAJ30491.1 - 4.8e-88 294.2 0.0 6.7e-88 293.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ30491.1 - 6e-19 68.3 0.0 2.3e-18 66.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ30491.1 - 3.6e-06 26.5 0.0 1.3e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain Diphthamide_syn PF01866.12 OAJ30492.1 - 2.4e-73 247.0 0.0 8.2e-32 110.6 0.0 5.8 4 1 0 4 4 4 4 Putative diphthamide synthesis protein Arrestin_N PF00339.24 OAJ30493.1 - 0.0019 18.0 0.0 0.0054 16.5 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain HMG_box PF00505.14 OAJ30495.1 - 1.4e-08 34.8 1.3 0.00012 22.3 0.2 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box 6PF2K PF01591.13 OAJ30496.1 - 2.3e-63 213.2 0.0 3.2e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 OAJ30496.1 - 2.2e-21 76.6 0.0 5.3e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 OAJ30496.1 - 1.9e-05 24.5 0.0 3.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ30496.1 - 0.0019 18.9 0.7 0.02 15.6 0.0 2.8 3 1 1 4 4 4 1 AAA domain KTI12 PF08433.5 OAJ30496.1 - 0.0019 17.4 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Pkinase PF00069.20 OAJ30498.1 - 3.8e-11 42.6 0.0 7.3e-11 41.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ30498.1 - 1.2e-05 24.5 0.0 0.055 12.5 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 OAJ30500.1 - 1.8e-06 27.3 0.0 4.8e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ30500.1 - 0.0026 16.8 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Peptidase_M43 PF05572.8 OAJ30502.1 - 3.6e-11 42.9 0.1 8.4e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A CRAL_TRIO PF00650.15 OAJ30503.1 - 1.4e-11 44.1 0.0 7.5e-11 41.7 0.0 2.0 1 1 0 1 1 1 1 CRAL/TRIO domain Bunya_NS-S PF01104.12 OAJ30503.1 - 0.15 11.5 1.1 0.31 10.5 0.7 1.4 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s Cellulase PF00150.13 OAJ30504.1 - 7.8e-12 44.9 5.9 1.1e-11 44.4 4.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Redoxin PF08534.5 OAJ30505.1 - 1.2e-33 115.7 0.0 1.3e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAJ30505.1 - 2.8e-10 39.9 0.0 3.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Oxidored_FMN PF00724.15 OAJ30506.1 - 8e-62 209.1 0.0 2.1e-56 191.3 0.0 2.1 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_U32 PF01136.14 OAJ30506.1 - 0.16 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family U32 Peptidase_M19 PF01244.16 OAJ30510.1 - 0.021 13.7 1.6 0.28 10.0 0.4 2.2 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) HTH_Tnp_Tc5 PF03221.11 OAJ30511.1 - 4.5e-05 23.1 0.0 8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 OAJ30511.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease FUN14 PF04930.10 OAJ30512.1 - 1.2e-20 73.6 0.8 2e-20 72.9 0.5 1.3 1 0 0 1 1 1 1 FUN14 family p450 PF00067.17 OAJ30513.1 - 2.5e-72 243.8 0.0 3.3e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ubiquitin PF00240.18 OAJ30514.1 - 2.2e-19 68.5 0.0 7.3e-10 38.1 0.2 2.1 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 OAJ30514.1 - 1.7e-12 46.8 0.1 3e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 OAJ30515.1 - 1.5e-17 62.6 0.0 3.7e-07 29.4 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 OAJ30515.1 - 1.3e-11 44.0 0.0 1.9e-06 27.4 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like FlgD_ig PF13860.1 OAJ30515.1 - 0.015 15.0 1.2 1.2 8.9 0.0 3.0 3 0 0 3 3 3 0 FlgD Ig-like domain DUF3244 PF11589.3 OAJ30515.1 - 0.028 14.1 0.3 2 8.1 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3244) DUF4551 PF15087.1 OAJ30515.1 - 0.17 10.2 0.0 0.24 9.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Nro1 PF12753.2 OAJ30516.1 - 0.0047 15.9 0.8 0.0055 15.7 0.5 1.1 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 NAD_binding_9 PF13454.1 OAJ30516.1 - 0.024 14.4 0.7 0.038 13.7 0.5 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF4238 PF14022.1 OAJ30516.1 - 0.1 11.8 0.1 0.11 11.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) AKNA PF12443.3 OAJ30516.1 - 0.15 12.1 1.5 0.27 11.2 1.1 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor DUF1127 PF06568.6 OAJ30516.1 - 0.18 11.2 0.1 0.18 11.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) FdhE PF04216.7 OAJ30516.1 - 0.19 11.4 3.2 0.22 11.2 1.9 1.3 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation Atg14 PF10186.4 OAJ30516.1 - 0.2 10.5 5.4 0.21 10.4 3.2 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tox-ODYAM1 PF15642.1 OAJ30516.1 - 0.26 9.9 2.4 0.32 9.5 1.7 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Hpt PF01627.18 OAJ30517.1 - 0.047 13.6 1.5 0.21 11.5 0.6 2.1 1 1 1 2 2 2 0 Hpt domain PgaD PF13994.1 OAJ30517.1 - 0.13 11.7 0.1 0.44 10.0 0.0 1.8 1 1 1 2 2 2 0 PgaD-like protein BAR_3_WASP_bdg PF10456.4 OAJ30517.1 - 0.15 11.2 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein SF3b1 PF08920.5 OAJ30518.1 - 7.6e-30 103.8 0.4 3.4e-29 101.7 0.0 2.2 2 1 0 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 OAJ30518.1 - 7.5e-17 61.3 5.4 1.1e-05 25.6 0.1 7.4 6 2 4 10 10 10 5 HEAT repeats HEAT_EZ PF13513.1 OAJ30518.1 - 6.4e-12 45.5 5.0 0.13 12.8 0.0 8.1 7 3 2 9 9 9 3 HEAT-like repeat HEAT PF02985.17 OAJ30518.1 - 5.1e-09 35.4 6.7 0.67 10.1 0.1 9.5 10 0 0 10 10 10 1 HEAT repeat Adaptin_N PF01602.15 OAJ30518.1 - 8.4e-08 30.9 0.5 0.0005 18.5 0.0 3.0 1 1 1 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 OAJ30518.1 - 8.8e-06 26.0 0.3 0.95 9.8 0.0 5.3 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 OAJ30518.1 - 0.00019 20.8 0.3 0.57 9.4 0.0 3.7 4 0 0 4 4 4 1 CLASP N terminal NUC173 PF08161.7 OAJ30518.1 - 0.00035 19.9 0.2 2.6 7.3 0.0 4.3 3 1 1 4 4 4 1 NUC173 domain Dopey_N PF04118.9 OAJ30518.1 - 0.01 14.6 0.5 0.1 11.3 0.0 2.7 3 0 0 3 3 3 0 Dopey, N-terminal MMS19_N PF14500.1 OAJ30518.1 - 0.013 14.7 0.0 27 3.8 0.0 3.6 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 OAJ30518.1 - 0.051 12.2 0.0 26 3.3 0.0 3.9 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal TPR_12 PF13424.1 OAJ30519.1 - 1.4e-09 37.7 18.3 0.0043 16.9 0.0 6.6 6 3 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ30519.1 - 2.4e-09 36.6 8.2 0.0021 17.6 0.4 5.2 4 2 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 OAJ30519.1 - 5.5e-08 32.1 7.7 0.76 9.8 0.3 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ30519.1 - 8.3e-05 22.0 0.1 9.9 6.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ30519.1 - 0.00053 20.5 15.6 0.014 16.0 1.3 5.5 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ30519.1 - 0.00095 18.6 1.8 5 6.9 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3856 PF12968.2 OAJ30519.1 - 0.0017 18.1 0.9 0.0068 16.2 0.2 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_7 PF13176.1 OAJ30519.1 - 0.0021 17.6 3.3 0.47 10.3 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat DSHCT PF08148.7 OAJ30519.1 - 0.012 14.9 0.1 0.092 11.9 0.0 2.4 2 0 0 2 2 2 0 DSHCT (NUC185) domain TPR_6 PF13174.1 OAJ30519.1 - 0.013 15.8 6.1 0.89 10.1 0.0 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ30519.1 - 0.017 15.4 12.5 0.1 12.9 0.9 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ30519.1 - 0.023 15.2 24.5 10 7.0 0.0 8.7 7 3 3 10 10 9 0 Tetratricopeptide repeat MIT PF04212.13 OAJ30519.1 - 1.3 8.9 6.5 25 4.8 0.0 4.6 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain ubiquitin PF00240.18 OAJ30520.1 - 7.7e-10 38.0 0.1 5.8e-05 22.4 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 OAJ30520.1 - 7.9e-05 22.2 0.0 0.0015 18.2 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.3 OAJ30520.1 - 0.0045 17.2 0.0 0.38 11.0 0.0 2.6 2 1 1 3 3 3 1 Nuclear pore localisation protein NPL4 USP7_C2 PF14533.1 OAJ30520.1 - 0.0052 16.2 0.0 0.19 11.1 0.0 1.4 1 1 1 2 2 2 2 Ubiquitin-specific protease C-terminal FERM_N PF09379.5 OAJ30520.1 - 0.039 14.0 0.1 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 FERM N-terminal domain Telomere_Sde2 PF13019.1 OAJ30520.1 - 0.048 13.3 0.0 0.42 10.3 0.0 1.9 1 1 1 2 2 2 0 Telomere stability and silencing RBD PF02196.10 OAJ30520.1 - 0.11 12.2 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Raf-like Ras-binding domain ubiquitin PF00240.18 OAJ30521.1 - 5.9e-30 102.4 0.6 7.1e-12 44.5 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 OAJ30521.1 - 8.3e-17 60.6 0.4 9.2e-08 31.6 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF4634 PF15465.1 OAJ30521.1 - 0.019 15.1 0.2 0.15 12.2 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4634) FlgD_ig PF13860.1 OAJ30521.1 - 0.082 12.6 0.6 10 5.9 0.0 2.4 2 0 0 2 2 2 0 FlgD Ig-like domain USP7_C2 PF14533.1 OAJ30521.1 - 0.086 12.2 0.2 0.92 8.8 0.0 2.4 2 1 1 3 3 3 0 Ubiquitin-specific protease C-terminal Sigma70_ner PF04546.8 OAJ30522.1 - 0.3 10.6 3.9 0.52 9.8 2.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 OAJ30522.1 - 2.1 8.6 15.6 4.8 7.4 10.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.7 OAJ30522.1 - 3.4 5.4 7.8 4.3 5.1 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 OAJ30522.1 - 4.2 6.3 9.1 9.9 5.1 6.3 1.6 1 0 0 1 1 1 0 BUD22 Vps52 PF04129.7 OAJ30523.1 - 2.7e-39 135.0 0.0 1.7e-36 125.8 0.0 2.3 2 0 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.4 OAJ30523.1 - 7.9e-05 20.9 0.0 0.00012 20.3 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 PPP4R2 PF09184.6 OAJ30523.1 - 0.012 15.1 3.2 0.025 14.1 2.2 1.4 1 0 0 1 1 1 0 PPP4R2 PBP1_TM PF14812.1 OAJ30523.1 - 0.09 13.0 8.2 0.18 12.1 5.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Daxx PF03344.10 OAJ30523.1 - 0.12 10.8 5.2 0.23 9.9 3.6 1.3 1 0 0 1 1 1 0 Daxx Family GP41 PF00517.12 OAJ30523.1 - 0.29 10.6 0.1 0.55 9.7 0.1 1.4 1 0 0 1 1 1 0 Retroviral envelope protein CENP-B_dimeris PF09026.5 OAJ30523.1 - 0.91 9.8 15.6 3.6 7.8 10.8 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.7 OAJ30523.1 - 0.94 9.1 13.1 4.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 OAJ30523.1 - 1.1 8.7 12.8 1.9 8.0 8.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 OAJ30523.1 - 8.6 6.1 8.5 19 5.0 5.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.7 OAJ30523.1 - 9.3 4.0 11.7 0.88 7.4 5.0 1.4 2 0 0 2 2 2 0 Nop14-like family Sigma70_ner PF04546.8 OAJ30523.1 - 9.4 5.7 11.7 1.9 8.0 5.4 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region NPR2 PF06218.6 OAJ30524.1 - 2.1e-105 352.8 2.9 3.3e-60 203.9 0.1 4.2 3 1 0 3 3 3 3 Nitrogen permease regulator 2 NPR3 PF03666.8 OAJ30524.1 - 0.0033 16.0 4.2 0.065 11.7 0.0 2.7 2 1 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 ATP_bind_1 PF03029.12 OAJ30525.1 - 8.7e-82 274.2 0.0 1.4e-80 270.2 0.0 1.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 OAJ30525.1 - 3.8e-08 32.9 0.0 9.5e-08 31.6 0.0 1.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 OAJ30525.1 - 1.5e-05 25.7 0.1 6.5e-05 23.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ30525.1 - 8.1e-05 22.7 0.2 0.0039 17.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 OAJ30525.1 - 0.00022 20.8 0.0 0.00068 19.1 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 OAJ30525.1 - 0.00085 19.2 0.1 0.0023 17.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 OAJ30525.1 - 0.0012 18.3 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.1 OAJ30525.1 - 0.002 18.1 0.0 0.021 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 OAJ30525.1 - 0.0031 16.9 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein KaiC PF06745.8 OAJ30525.1 - 0.0033 16.5 0.0 0.0088 15.1 0.0 1.7 1 1 0 1 1 1 1 KaiC AAA_29 PF13555.1 OAJ30525.1 - 0.0041 16.6 0.0 0.0073 15.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.1 OAJ30525.1 - 0.0059 16.2 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 OAJ30525.1 - 0.011 14.5 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 ArgK protein MobB PF03205.9 OAJ30525.1 - 0.012 15.3 0.0 0.032 13.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 OAJ30525.1 - 0.015 14.2 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 OAJ30525.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.1 OAJ30525.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 OAJ30525.1 - 0.019 14.3 0.0 0.25 10.7 0.0 2.4 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain MipZ PF09140.6 OAJ30525.1 - 0.03 13.3 0.0 0.22 10.5 0.0 2.1 1 1 0 1 1 1 0 ATPase MipZ AAA_18 PF13238.1 OAJ30525.1 - 0.036 14.3 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain KTI12 PF08433.5 OAJ30525.1 - 0.054 12.6 0.0 0.26 10.4 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RNA_helicase PF00910.17 OAJ30525.1 - 0.058 13.5 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 OAJ30525.1 - 0.066 12.6 0.2 0.52 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 OAJ30525.1 - 0.068 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 OAJ30525.1 - 0.086 13.0 0.0 1.1 9.4 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ArsA_ATPase PF02374.10 OAJ30525.1 - 0.091 11.7 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase CobU PF02283.11 OAJ30525.1 - 0.1 12.0 0.1 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_14 PF13173.1 OAJ30525.1 - 0.1 12.5 0.0 0.46 10.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 OAJ30525.1 - 0.11 12.3 0.1 0.19 11.5 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF87 CAF1A PF12253.3 OAJ30526.1 - 1.6e-21 76.1 9.8 1.6e-21 76.1 6.8 3.5 3 1 0 3 3 3 1 Chromatin assembly factor 1 subunit A Borrelia_P83 PF05262.6 OAJ30526.1 - 0.026 12.8 34.7 0.047 11.9 24.0 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein HGTP_anticodon2 PF12745.2 OAJ30526.1 - 0.19 10.8 19.8 0.52 9.4 13.7 1.7 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs G-7-MTase PF12803.2 OAJ30526.1 - 3 6.9 10.2 1.2 8.1 5.3 1.6 1 1 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DUF2146 PF10220.4 OAJ30526.1 - 3.3 5.5 20.4 5.8 4.7 14.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Parvo_coat PF00740.13 OAJ30526.1 - 9 5.1 12.7 18 4.1 8.8 1.5 1 0 0 1 1 1 0 Parvovirus coat protein VP2 GAS2 PF02187.12 OAJ30527.1 - 2.4e-08 33.6 0.0 5.9e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Gp-FAR-1 PF05823.7 OAJ30527.1 - 0.14 12.0 7.0 12 5.7 0.1 4.6 4 1 0 4 4 4 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FCH PF00611.18 OAJ30527.1 - 0.17 12.1 3.9 6.4 7.0 0.3 4.1 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain zf-MYND PF01753.13 OAJ30528.1 - 1.1e-09 38.0 13.7 1.1e-09 38.0 9.5 2.7 2 1 1 3 3 3 1 MYND finger SET PF00856.23 OAJ30528.1 - 4.7e-06 27.0 0.0 1.4e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 SET domain DNA_RNApol_7kD PF03604.8 OAJ30528.1 - 0.46 9.9 5.0 10 5.6 0.8 3.2 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-Mss51 PF13824.1 OAJ30528.1 - 3.7 7.4 10.1 1.4 8.8 2.7 2.9 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 AA_kinase PF00696.23 OAJ30529.1 - 6.4e-30 104.4 0.4 8.1e-30 104.1 0.3 1.1 1 0 0 1 1 1 1 Amino acid kinase family H_kinase_N PF12282.3 OAJ30529.1 - 0.09 12.3 0.1 10 5.7 0.0 2.2 2 0 0 2 2 2 0 Signal transduction histidine kinase Dynamin_N PF00350.18 OAJ30530.1 - 1.5e-40 138.7 0.0 2.7e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 OAJ30530.1 - 0.00017 20.4 0.0 0.00049 18.9 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 OAJ30530.1 - 0.0013 18.7 0.0 0.0044 16.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAJ30530.1 - 0.0064 16.9 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Peptidase_S58 PF03576.9 OAJ30530.1 - 0.072 12.2 5.3 0.043 13.0 2.3 1.6 2 0 0 2 2 2 0 Peptidase family S58 GTP_EFTU PF00009.22 OAJ30530.1 - 0.1 12.0 0.1 5.2 6.4 0.1 3.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_21 PF13304.1 OAJ30530.1 - 0.2 11.5 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP40_C PF05022.7 OAJ30533.1 - 8.5e-30 103.0 5.6 2.6e-29 101.5 3.9 1.9 1 0 0 1 1 1 1 SRP40, C-terminal domain Transposase_21 PF02992.9 OAJ30535.1 - 2.1e-14 53.1 0.0 3.7e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ30535.1 - 2e-06 27.2 0.1 4.1e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) PBP1_TM PF14812.1 OAJ30535.1 - 0.014 15.6 2.7 0.014 15.6 1.9 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TLP-20 PF06088.6 OAJ30535.1 - 0.76 9.4 3.3 1.8 8.2 2.3 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) TFIIA PF03153.8 OAJ30536.1 - 0.64 9.8 10.3 0.067 13.0 3.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit vATP-synt_AC39 PF01992.11 OAJ30538.1 - 7.6e-98 327.7 0.0 8.5e-98 327.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit NOA36 PF06524.7 OAJ30540.1 - 8.3 5.5 7.4 13 4.9 5.1 1.2 1 0 0 1 1 1 0 NOA36 protein 3Beta_HSD PF01073.14 OAJ30541.1 - 1.8e-19 69.4 0.0 1.3e-18 66.6 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAJ30541.1 - 7.2e-17 61.6 0.0 1.1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ30541.1 - 3.5e-14 53.2 0.1 1.7e-13 50.9 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAJ30541.1 - 2.1e-11 43.2 0.0 1.9e-10 40.0 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 OAJ30541.1 - 6.2e-08 32.1 0.0 8.9e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 OAJ30541.1 - 2.7e-05 23.2 0.1 4.3e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 OAJ30541.1 - 0.00097 19.0 0.5 0.004 17.0 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_2 PF03446.10 OAJ30541.1 - 0.0046 16.8 0.0 0.028 14.2 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.5 OAJ30541.1 - 0.061 12.9 0.4 1.2 8.7 0.3 2.2 1 1 0 1 1 1 0 KR domain Ribosomal_S8 PF00410.14 OAJ30542.1 - 2.2e-19 69.5 0.0 3.3e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 DUF3385 PF11865.3 OAJ30543.1 - 9e-48 162.2 0.0 1.9e-44 151.4 0.0 3.7 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) HEAT PF02985.17 OAJ30543.1 - 3.4e-16 57.7 15.3 0.041 13.9 0.1 10.5 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 OAJ30543.1 - 3.7e-16 59.1 34.3 0.00059 20.0 0.1 11.1 7 3 6 13 13 11 7 HEAT repeats Cnd1 PF12717.2 OAJ30543.1 - 1.3e-05 25.1 3.3 0.54 10.0 0.3 6.0 5 1 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 FAT PF02259.18 OAJ30543.1 - 2.9e-05 23.2 0.3 7.7e-05 21.8 0.2 1.8 1 0 0 1 1 1 1 FAT domain Adaptin_N PF01602.15 OAJ30543.1 - 0.00026 19.4 6.1 0.47 8.7 0.3 4.7 4 1 1 5 5 5 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 OAJ30543.1 - 0.0029 17.9 0.2 8.9 6.7 0.0 5.6 5 1 0 5 5 5 1 Vacuolar 14 Fab1-binding region VHS PF00790.14 OAJ30543.1 - 0.0051 16.4 0.1 11 5.7 0.0 4.0 5 0 0 5 5 5 1 VHS domain TPR_11 PF13414.1 OAJ30543.1 - 0.02 14.5 0.2 1.1 8.9 0.0 2.9 2 0 0 2 2 2 0 TPR repeat HEAT_EZ PF13513.1 OAJ30543.1 - 0.031 14.7 0.5 0.031 14.7 0.4 13.5 14 3 6 20 20 18 0 HEAT-like repeat IBN_N PF03810.14 OAJ30543.1 - 0.19 11.6 1.4 2.6 8.0 0.0 3.7 4 0 0 4 4 4 0 Importin-beta N-terminal domain ACPS PF01648.15 OAJ30544.1 - 2.8e-19 69.0 0.2 6e-19 67.9 0.2 1.6 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily ABC_membrane PF00664.18 OAJ30545.1 - 1.9e-66 224.3 23.2 1.9e-36 125.8 3.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ30545.1 - 1.6e-60 203.3 0.0 1.2e-32 113.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAJ30545.1 - 1.6e-10 40.5 0.5 0.0036 16.5 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAJ30545.1 - 7.9e-10 39.1 0.2 0.00028 20.9 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA_17 PF13207.1 OAJ30545.1 - 4.3e-08 34.0 0.5 0.00082 20.1 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 OAJ30545.1 - 4.2e-07 29.3 2.5 0.013 15.0 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 OAJ30545.1 - 3.1e-06 27.5 0.0 0.093 13.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 OAJ30545.1 - 1.2e-05 25.3 9.7 0.00029 20.8 0.3 4.1 2 2 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 OAJ30545.1 - 4.1e-05 22.8 0.2 0.022 13.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 OAJ30545.1 - 6.7e-05 22.3 0.1 0.49 9.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 OAJ30545.1 - 0.00028 21.0 2.4 0.18 11.9 0.5 3.7 2 1 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 OAJ30545.1 - 0.0005 18.7 1.4 0.24 9.9 0.0 3.0 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_5 PF07728.9 OAJ30545.1 - 0.003 17.2 0.6 1.7 8.3 0.0 4.0 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 OAJ30545.1 - 0.0079 15.7 0.5 0.86 9.0 0.1 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 OAJ30545.1 - 0.015 14.7 7.9 4.1 6.7 0.2 4.0 4 0 0 4 4 4 0 AAA-like domain AAA_33 PF13671.1 OAJ30545.1 - 0.021 14.7 1.4 5.9 6.7 0.0 3.7 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 OAJ30545.1 - 0.023 14.1 0.2 8.3 5.8 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 OAJ30545.1 - 0.033 14.0 3.9 1.1 9.0 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 Sigma54_activat PF00158.21 OAJ30545.1 - 0.038 13.4 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain APS_kinase PF01583.15 OAJ30545.1 - 0.044 13.4 0.3 2.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_23 PF13476.1 OAJ30545.1 - 0.047 14.0 0.9 2.9 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 OAJ30545.1 - 0.052 13.7 0.2 3.2 7.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 OAJ30545.1 - 0.11 12.4 0.0 2.2 8.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 OAJ30545.1 - 0.12 11.9 1.1 4.1 7.0 0.0 3.2 3 0 0 3 3 2 0 NACHT domain KaiC PF06745.8 OAJ30545.1 - 0.17 10.9 2.7 4.2 6.4 0.1 2.7 3 0 0 3 3 2 0 KaiC G-alpha PF00503.15 OAJ30545.1 - 0.19 10.3 0.7 0.77 8.3 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit MobB PF03205.9 OAJ30545.1 - 0.21 11.2 0.3 16 5.2 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 OAJ30545.1 - 0.24 11.9 0.4 15 6.0 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein PRK PF00485.13 OAJ30545.1 - 0.29 10.6 0.9 2.2 7.8 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 OAJ30545.1 - 0.92 9.4 8.9 0.35 10.8 0.2 3.5 4 0 0 4 4 3 0 AAA domain HSP70 PF00012.15 OAJ30546.1 - 3.4e-29 101.2 7.1 1e-24 86.4 0.0 2.8 3 0 0 3 3 3 2 Hsp70 protein Glyco_transf_20 PF00982.16 OAJ30547.1 - 9.5e-142 472.7 0.0 2e-130 435.4 0.0 2.6 2 1 0 3 3 3 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 OAJ30547.1 - 1.2e-77 260.0 0.0 1.8e-77 259.3 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 OAJ30547.1 - 1.9e-05 24.4 0.0 0.0078 15.8 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase rve_3 PF13683.1 OAJ30547.1 - 0.0018 17.7 0.0 0.0054 16.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain S6PP PF05116.8 OAJ30547.1 - 0.0024 17.2 0.1 0.012 14.8 0.0 2.0 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Pox_A_type_inc PF04508.7 OAJ30547.1 - 0.69 9.8 2.1 4 7.4 0.6 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat GMC_oxred_N PF00732.14 OAJ30548.1 - 3.9e-61 206.7 0.0 9.5e-61 205.5 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ30548.1 - 5.8e-31 107.7 0.1 1.2e-30 106.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAJ30548.1 - 3.1e-08 32.9 0.0 9.6e-08 31.3 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ30548.1 - 6.3e-05 22.0 0.0 0.00048 19.0 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 OAJ30548.1 - 0.00017 21.5 0.0 0.00041 20.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAJ30548.1 - 0.0002 21.4 0.1 0.078 13.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ30548.1 - 0.00042 20.2 0.2 0.051 13.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAJ30548.1 - 0.0012 17.8 0.2 0.0018 17.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 OAJ30548.1 - 0.019 13.4 0.4 0.041 12.3 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 OAJ30548.1 - 0.086 13.2 0.2 1.6 9.2 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Dynactin_p62 PF05502.8 OAJ30549.1 - 1.1e-67 228.9 8.8 9.3e-46 156.5 7.7 2.2 2 0 0 2 2 2 2 Dynactin p62 family UbiA PF01040.13 OAJ30550.1 - 3.6e-31 108.3 22.9 1e-30 106.8 15.9 1.6 1 1 0 1 1 1 1 UbiA prenyltransferase family R3H PF01424.17 OAJ30551.1 - 9.3e-11 41.2 0.5 1.6e-10 40.4 0.4 1.4 1 0 0 1 1 1 1 R3H domain DER1 PF04511.10 OAJ30553.1 - 3.6e-47 160.4 1.4 4.1e-47 160.2 1.0 1.0 1 0 0 1 1 1 1 Der1-like family Serglycin PF04360.7 OAJ30554.1 - 0.0032 17.2 5.5 0.0032 17.2 3.8 15.4 6 6 8 14 14 14 2 Serglycin Usp PF00582.21 OAJ30555.1 - 2.8e-18 66.4 0.0 2.8e-18 66.4 0.0 3.7 3 2 1 4 4 4 2 Universal stress protein family HSP70 PF00012.15 OAJ30556.1 - 9.9e-156 519.1 0.1 1.3e-155 518.7 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAJ30556.1 - 2e-08 33.2 0.1 1.3e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Not1 PF04054.10 OAJ30557.1 - 6.4e-106 354.4 0.0 1.9e-105 352.8 0.0 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 OAJ30557.1 - 4.9e-54 182.0 3.6 1.1e-53 180.9 2.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) TPM PF04536.9 OAJ30557.1 - 0.099 12.5 0.1 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase YppF PF14178.1 OAJ30557.1 - 0.14 11.7 0.4 1.2 8.7 0.1 2.6 3 0 0 3 3 3 0 YppF-like protein APH PF01636.18 OAJ30558.1 - 0.057 13.1 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M1 PF01433.15 OAJ30559.1 - 3.2e-100 335.9 0.0 5.6e-64 216.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 OAJ30559.1 - 2.2e-56 191.4 0.1 4e-56 190.6 0.1 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 OAJ30559.1 - 1.3e-14 54.3 0.0 2.7e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Tht1 PF04163.7 OAJ30560.1 - 0.047 12.0 0.1 0.047 12.0 0.1 1.8 1 1 1 2 2 2 0 Tht1-like nuclear fusion protein MRP-S23 PF10484.4 OAJ30560.1 - 0.6 10.0 3.6 1.7 8.5 0.8 2.6 2 1 1 3 3 3 0 Mitochondrial ribosomal protein S23 GrpE PF01025.14 OAJ30560.1 - 0.81 9.2 11.8 0.052 13.0 1.6 2.2 2 0 0 2 2 2 0 GrpE ApoLp-III PF07464.6 OAJ30560.1 - 1.2 9.1 10.3 0.27 11.2 3.2 2.3 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Nnf1 PF03980.9 OAJ30561.1 - 2.7e-06 27.3 4.9 2.7e-06 27.3 3.4 1.8 2 0 0 2 2 2 1 Nnf1 IFT57 PF10498.4 OAJ30561.1 - 0.00031 19.5 3.6 0.00054 18.8 2.5 1.4 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DASH_Spc34 PF08657.5 OAJ30561.1 - 0.0047 16.6 1.9 0.0047 16.6 1.3 2.1 3 0 0 3 3 3 1 DASH complex subunit Spc34 PrgH PF09480.5 OAJ30561.1 - 0.023 13.5 0.7 0.035 12.9 0.5 1.3 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) Atg14 PF10186.4 OAJ30561.1 - 0.97 8.3 9.8 1.7 7.5 6.8 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Rbsn PF11464.3 OAJ30561.1 - 1.3 8.6 6.0 0.44 10.1 0.4 2.8 4 0 0 4 4 4 0 Rabenosyn Rab binding domain DUF972 PF06156.8 OAJ30561.1 - 5.4 7.4 12.4 1.5 9.1 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 OAJ30561.1 - 6.2 6.4 8.3 2.5 7.7 3.8 1.9 2 0 0 2 2 2 0 Mnd1 family DinB PF05163.7 OAJ30561.1 - 8.3 6.0 8.2 6.4 6.4 0.1 2.3 1 1 0 2 2 2 0 DinB family Med6 PF04934.9 OAJ30562.1 - 3.6e-42 143.2 0.0 4.2e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component Nucleoplasmin PF03066.10 OAJ30562.1 - 0.005 16.3 0.3 0.0058 16.1 0.2 1.3 1 0 0 1 1 1 1 Nucleoplasmin Mpp10 PF04006.7 OAJ30562.1 - 0.037 12.4 1.1 0.048 12.0 0.8 1.1 1 0 0 1 1 1 0 Mpp10 protein Sigma70_ner PF04546.8 OAJ30562.1 - 0.13 11.8 1.4 0.18 11.3 0.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 OAJ30562.1 - 3.2 8.0 11.9 4.9 7.4 7.5 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2457 PF10446.4 OAJ30562.1 - 3.7 6.1 12.1 5.1 5.7 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Rad10 PF03834.9 OAJ30563.1 - 1.9e-31 107.5 0.1 3.5e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 OAJ30563.1 - 9.4e-08 32.1 0.0 2.4e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 OAJ30563.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF2360 PF10152.4 OAJ30563.1 - 0.04 14.1 0.3 0.076 13.2 0.2 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) K_channel_TID PF07941.6 OAJ30563.1 - 0.11 12.7 2.0 0.26 11.5 1.4 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Apc3 PF12895.2 OAJ30563.1 - 0.13 12.3 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 RasGAP PF00616.14 OAJ30565.1 - 2.2e-55 187.3 0.0 5.3e-55 186.1 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 OAJ30565.1 - 1.1e-39 135.3 0.2 3.1e-39 133.9 0.1 1.8 1 0 0 1 1 1 1 RasGAP C-terminus DUF972 PF06156.8 OAJ30565.1 - 0.011 16.0 0.6 4.8 7.5 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF2418 PF10332.4 OAJ30566.1 - 1.1e-18 67.3 1.0 1.1e-18 67.3 0.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Myc_N PF01056.13 OAJ30566.1 - 0.0024 17.1 3.0 0.0024 17.1 2.0 1.7 2 0 0 2 2 2 1 Myc amino-terminal region Nucleo_P87 PF07267.6 OAJ30566.1 - 0.041 12.5 1.1 0.058 12.0 0.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nucleoplasmin PF03066.10 OAJ30566.1 - 0.099 12.1 13.8 0.17 11.3 9.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 OAJ30566.1 - 0.16 9.8 7.4 0.21 9.4 5.1 1.1 1 0 0 1 1 1 0 Nop14-like family Cytomega_UL84 PF06284.6 OAJ30566.1 - 0.64 8.3 3.3 1 7.7 2.3 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF2457 PF10446.4 OAJ30566.1 - 0.8 8.3 11.3 1.9 7.1 7.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) VID27 PF08553.5 OAJ30566.1 - 1.1 7.4 4.8 1.5 6.9 3.3 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Daxx PF03344.10 OAJ30566.1 - 4.1 5.7 11.9 7.4 4.9 8.2 1.3 1 0 0 1 1 1 0 Daxx Family PBP1_TM PF14812.1 OAJ30566.1 - 7.3 6.9 17.2 1.4 9.2 9.0 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ferric_reduct PF01794.14 OAJ30568.1 - 2.4e-16 59.9 10.9 2.4e-16 59.9 7.6 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 OAJ30568.1 - 4.5e-13 49.3 0.0 8.8e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 OAJ30568.1 - 9.5e-07 28.6 0.0 6e-05 22.8 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 OAJ30568.1 - 0.012 16.1 0.0 0.11 13.0 0.0 2.4 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4405 PF14358.1 OAJ30568.1 - 0.056 13.5 7.8 2.4 8.3 0.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) RF-1 PF00472.15 OAJ30569.1 - 9e-38 128.5 1.8 2.1e-37 127.3 1.2 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 OAJ30569.1 - 6.5e-33 112.8 0.0 2.1e-32 111.2 0.0 1.9 1 0 0 1 1 1 1 PCRF domain Ald_Xan_dh_C2 PF02738.13 OAJ30570.1 - 2.1e-175 584.1 0.0 2.8e-175 583.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.17 OAJ30570.1 - 1.4e-30 105.6 0.0 3.2e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.16 OAJ30570.1 - 9.5e-28 96.7 0.0 1.7e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.15 OAJ30570.1 - 2.6e-24 84.8 0.1 5.5e-24 83.8 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.12 OAJ30570.1 - 3.2e-20 72.0 1.3 2e-19 69.4 0.0 3.0 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.22 OAJ30570.1 - 1.9e-06 27.5 0.1 2.2e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain 4HBT PF03061.17 OAJ30572.1 - 4.1e-09 36.4 0.0 7.3e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 OAJ30572.1 - 0.066 13.1 0.0 0.15 12.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4442) Herpes_UL33 PF03581.8 OAJ30572.1 - 0.072 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL33-like protein Nucleoplasmin PF03066.10 OAJ30573.1 - 0.005 16.3 6.6 0.0055 16.2 4.5 1.2 1 0 0 1 1 1 1 Nucleoplasmin DUF4611 PF15387.1 OAJ30573.1 - 0.014 15.4 5.8 0.018 15.1 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CDC45 PF02724.9 OAJ30573.1 - 0.041 11.9 1.6 0.037 12.0 1.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 OAJ30573.1 - 0.058 12.1 12.6 0.055 12.1 8.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Bd3614_N PF14442.1 OAJ30573.1 - 0.062 13.2 9.6 0.073 13.0 6.6 1.1 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Voldacs PF03517.8 OAJ30573.1 - 0.11 12.3 2.7 0.12 12.2 1.9 1.1 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Sigma70_ner PF04546.8 OAJ30573.1 - 0.32 10.5 7.3 0.36 10.4 5.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region ANAPC15 PF15243.1 OAJ30573.1 - 0.36 10.9 6.5 0.45 10.6 4.5 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 CENP-B_dimeris PF09026.5 OAJ30573.1 - 0.4 10.9 10.9 0.43 10.8 7.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 OAJ30573.1 - 0.44 9.7 6.5 0.39 9.9 4.5 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.6 OAJ30573.1 - 0.5 10.1 5.6 0.54 10.0 3.9 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.1 OAJ30573.1 - 1.2 8.8 3.4 1.3 8.6 2.4 1.1 1 0 0 1 1 1 0 FAM176 family Tom22 PF04281.8 OAJ30573.1 - 2 7.9 5.7 2.4 7.7 4.0 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Sporozoite_P67 PF05642.6 OAJ30573.1 - 2.8 5.6 5.0 2.5 5.8 3.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 OAJ30573.1 - 4.3 7.7 14.9 5.3 7.4 10.3 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3295 PF11702.3 OAJ30573.1 - 5.5 5.8 6.8 5.2 5.9 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Cwf_Cwc_15 PF04889.7 OAJ30573.1 - 8.9 5.9 10.6 9.8 5.8 7.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein WLM PF08325.5 OAJ30574.1 - 1.1e-42 146.0 0.3 4.7e-42 143.9 0.0 1.9 2 0 0 2 2 2 1 WLM domain zf-RanBP PF00641.13 OAJ30574.1 - 4.1e-06 25.7 3.2 6.7e-06 25.1 2.2 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others PhdYeFM_antitox PF02604.14 OAJ30574.1 - 0.041 13.4 0.3 0.11 12.1 0.2 1.7 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system DUF45 PF01863.12 OAJ30574.1 - 0.061 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 UvrD_C PF13361.1 OAJ30575.1 - 1.1e-70 238.8 0.0 3.9e-42 144.9 0.0 2.6 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 OAJ30575.1 - 3e-68 230.4 0.3 5.7e-68 229.5 0.2 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 OAJ30575.1 - 2.4e-11 43.6 0.0 6.9e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 OAJ30575.1 - 4.4e-11 42.3 0.9 1.4e-10 40.7 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 OAJ30575.1 - 1e-05 25.1 0.1 0.18 11.2 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 OAJ30575.1 - 0.002 17.4 0.2 0.86 8.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein SMC_Nse1 PF07574.8 OAJ30575.1 - 0.031 13.9 0.3 0.072 12.7 0.2 1.6 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex LAG1-DNAbind PF09271.6 OAJ30576.1 - 1.8e-22 80.3 1.9 5.9e-22 78.6 0.0 2.4 2 0 0 2 2 2 1 LAG1, DNA binding BTD PF09270.5 OAJ30576.1 - 6.6e-08 32.4 0.0 1.9e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain KTI12 PF08433.5 OAJ30577.1 - 1.5e-53 181.8 0.0 2.4e-53 181.0 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 OAJ30577.1 - 2.4e-08 33.9 0.2 4.9e-08 32.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ30577.1 - 0.00077 19.7 0.3 0.0057 16.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain Transket_pyr PF02779.19 OAJ30578.1 - 6.4e-47 159.3 0.0 1.3e-46 158.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 OAJ30578.1 - 5.3e-39 132.9 0.2 4.2e-38 130.0 0.0 2.4 3 0 0 3 3 3 1 Transketolase, C-terminal domain Med3 PF11593.3 OAJ30578.1 - 0.33 10.1 12.1 0.4 9.8 8.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Tannase PF07519.6 OAJ30580.1 - 1.1e-67 228.8 0.1 7e-66 222.8 0.1 2.2 1 1 0 1 1 1 1 Tannase and feruloyl esterase UAA PF08449.6 OAJ30582.1 - 1.8e-11 43.5 14.3 2.7e-07 29.8 0.2 2.1 2 0 0 2 2 2 2 UAA transporter family TPT PF03151.11 OAJ30582.1 - 6.8e-11 42.0 2.7 6.8e-11 42.0 1.9 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family PHO4 PF01384.15 OAJ30582.1 - 0.0017 17.1 0.2 0.0017 17.1 0.2 2.4 2 1 0 2 2 2 1 Phosphate transporter family EamA PF00892.15 OAJ30582.1 - 1.6 8.7 23.4 0.061 13.3 2.1 2.5 2 1 0 2 2 2 0 EamA-like transporter family zf-RING_2 PF13639.1 OAJ30583.1 - 1.2e-08 34.6 7.4 9.7e-08 31.7 3.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ30583.1 - 5.8e-08 32.6 5.0 5.8e-08 32.6 3.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ30583.1 - 1.1e-06 28.1 5.8 1.1e-06 28.1 4.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ30583.1 - 3e-06 26.8 7.3 2.4e-05 23.9 3.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAJ30583.1 - 0.00011 21.8 3.9 0.00027 20.5 2.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 OAJ30583.1 - 0.00018 21.1 5.9 0.00018 21.1 4.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain DUF1644 PF07800.7 OAJ30583.1 - 0.00082 19.2 1.5 0.093 12.5 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1644) zf-C3HC4_4 PF15227.1 OAJ30583.1 - 0.0018 18.1 6.2 0.0018 18.1 4.3 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 OAJ30583.1 - 1.2 9.0 3.9 3.2 7.6 1.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Aldedh PF00171.17 OAJ30584.1 - 7.2e-73 245.4 0.0 8.7e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NOZZLE PF08744.5 OAJ30586.1 - 0.056 12.7 2.9 0.042 13.2 0.5 1.7 2 0 0 2 2 2 0 Plant transcription factor NOZZLE Lyase_1 PF00206.15 OAJ30587.1 - 7.6e-93 311.1 0.0 1.2e-92 310.5 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 OAJ30587.1 - 2.2e-28 98.1 0.1 5.2e-28 96.9 0.1 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF726 PF05277.7 OAJ30588.1 - 6.9e-62 209.3 3.8 9.6e-62 208.8 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) MFS_1 PF07690.11 OAJ30589.1 - 1.7e-26 92.8 30.8 1.7e-26 92.8 21.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily PBP1_TM PF14812.1 OAJ30589.1 - 1.6 9.1 12.1 6.5 7.1 0.4 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 OAJ30589.1 - 4 6.9 11.2 0.31 10.5 1.2 2.1 2 0 0 2 2 2 0 Nucleoplasmin HisG PF01634.13 OAJ30590.1 - 4.5e-36 123.9 0.3 5.3e-35 120.3 0.2 2.2 1 1 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 OAJ30590.1 - 4.7e-26 90.5 0.1 1e-25 89.4 0.1 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain PMI_typeI PF01238.16 OAJ30591.1 - 1.3e-53 182.3 0.0 9.4e-53 179.5 0.0 2.1 1 1 0 1 1 1 1 Phosphomannose isomerase type I Ytp1 PF10355.4 OAJ30592.1 - 1.9e-66 224.0 16.5 1.1e-53 182.1 11.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.4 OAJ30592.1 - 9.3e-24 83.0 3.6 9.3e-24 83.0 2.5 3.5 3 1 1 4 4 4 1 Domain of unknown function (DUF2427) Antimicrobial10 PF08105.6 OAJ30592.1 - 0.011 15.2 0.8 0.028 14.0 0.6 1.6 1 0 0 1 1 1 0 Metchnikowin family YL1 PF05764.8 OAJ30593.1 - 0.00051 19.7 0.1 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Chromo PF00385.19 OAJ30595.1 - 0.046 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Homeobox_KN PF05920.6 OAJ30596.1 - 1e-16 60.2 3.2 2.1e-16 59.3 2.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 OAJ30596.1 - 5.6e-05 22.6 2.1 9.2e-05 21.9 0.7 1.9 2 0 0 2 2 2 1 Homeobox domain MFS_1 PF07690.11 OAJ30597.1 - 7.4e-26 90.6 71.4 2.8e-20 72.3 23.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 OAJ30597.1 - 0.084 12.6 11.8 0.15 11.8 0.6 3.6 3 0 0 3 3 3 0 MFS_1 like family PI3_PI4_kinase PF00454.22 OAJ30598.1 - 9.1e-33 113.6 0.0 5.5e-32 111.1 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 OAJ30598.1 - 9.4e-26 90.1 0.2 3.3e-25 88.3 0.0 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Ipi1_N PF12333.3 OAJ30598.1 - 0.022 14.7 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Utp14 PF04615.8 OAJ30600.1 - 4.8e-148 494.5 33.2 4.8e-148 494.5 23.0 2.9 1 1 1 2 2 2 1 Utp14 protein UPF0113 PF03657.8 OAJ30601.1 - 1.5e-11 44.2 0.0 2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) HMGL-like PF00682.14 OAJ30602.1 - 6.3e-72 242.0 0.5 1.1e-71 241.2 0.2 1.5 2 0 0 2 2 2 1 HMGL-like NUC173 PF08161.7 OAJ30603.1 - 5.2e-39 133.6 0.0 8.4e-38 129.7 0.0 2.6 1 1 0 1 1 1 1 NUC173 domain CAS_CSE1 PF03378.10 OAJ30603.1 - 0.21 9.8 0.0 0.53 8.5 0.0 1.6 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus CDC73 PF05179.9 OAJ30604.1 - 3.2e-42 144.7 1.1 2.1e-30 106.0 0.7 2.4 2 0 0 2 2 2 2 RNA pol II accessory factor, Cdc73 family DUF1436 PF07262.6 OAJ30604.1 - 0.23 10.9 0.0 0.86 9.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1436) Prenyltrans PF00432.16 OAJ30606.1 - 2.2e-29 100.6 11.0 1.1e-07 31.3 0.0 5.6 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 OAJ30606.1 - 1.5e-16 60.7 0.0 2.2e-14 53.8 0.0 3.4 3 0 0 3 3 3 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 OAJ30606.1 - 0.0011 18.9 0.0 0.0095 15.9 0.0 2.4 1 1 1 2 2 2 2 Prenyltransferase-like Cullin PF00888.17 OAJ30607.1 - 5.2e-24 84.7 0.0 3e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 Cullin family FeoC PF09012.5 OAJ30607.1 - 0.092 12.4 0.0 0.28 10.8 0.0 1.8 1 0 0 1 1 1 0 FeoC like transcriptional regulator ABC_tran PF00005.22 OAJ30608.1 - 5.6e-43 146.5 0.0 1e-20 74.4 0.0 3.1 2 1 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 OAJ30608.1 - 3.6e-23 81.2 2.1 3.6e-23 81.2 1.5 2.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 OAJ30608.1 - 1e-15 58.5 0.1 0.00017 21.6 0.0 4.4 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 OAJ30608.1 - 6.6e-13 48.4 0.1 8.3e-06 25.1 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 OAJ30608.1 - 2.1e-08 33.9 0.7 0.03 13.7 0.0 4.4 4 0 0 4 4 4 2 AAA-like domain AAA_22 PF13401.1 OAJ30608.1 - 2.7e-07 30.7 0.4 0.013 15.6 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 OAJ30608.1 - 4.9e-07 30.6 0.6 0.012 16.3 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 OAJ30608.1 - 6.5e-07 28.7 0.1 0.005 16.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 OAJ30608.1 - 1.1e-05 25.3 0.1 0.016 15.1 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase Miro PF08477.8 OAJ30608.1 - 1.3e-05 25.6 0.0 0.22 12.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 OAJ30608.1 - 5.2e-05 22.8 0.0 0.19 11.1 0.0 2.7 2 0 0 2 2 2 2 FtsK/SpoIIIE family NACHT PF05729.7 OAJ30608.1 - 6.5e-05 22.6 0.0 0.12 12.0 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.1 OAJ30608.1 - 0.00026 21.0 0.1 0.96 9.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 OAJ30608.1 - 0.00026 20.8 2.8 0.033 13.9 0.0 3.5 3 1 0 3 3 3 1 Domain of unknown function DUF87 AAA_33 PF13671.1 OAJ30608.1 - 0.00042 20.2 0.7 0.75 9.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 OAJ30608.1 - 0.00059 19.5 0.0 0.25 11.0 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 OAJ30608.1 - 0.00064 19.5 0.1 0.17 11.8 0.1 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 OAJ30608.1 - 0.00065 18.9 0.0 0.19 10.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 OAJ30608.1 - 0.00074 19.6 0.0 0.063 13.4 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 OAJ30608.1 - 0.00082 19.2 0.0 1.3 8.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 OAJ30608.1 - 0.0011 18.3 0.1 0.32 10.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 OAJ30608.1 - 0.0027 18.0 7.0 0.15 12.3 0.0 3.7 4 0 0 4 4 4 1 AAA domain T2SE PF00437.15 OAJ30608.1 - 0.0065 15.4 0.0 0.16 10.8 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein ArgK PF03308.11 OAJ30608.1 - 0.0085 14.8 0.0 1.3 7.7 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_16 PF13191.1 OAJ30608.1 - 0.0088 16.0 7.8 0.59 10.1 0.2 3.7 5 1 0 5 5 3 2 AAA ATPase domain AAA_15 PF13175.1 OAJ30608.1 - 0.012 14.6 0.9 4.9 6.0 0.0 3.4 4 0 0 4 4 4 0 AAA ATPase domain GTP_EFTU PF00009.22 OAJ30608.1 - 0.016 14.6 0.0 0.33 10.3 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MutS_V PF00488.16 OAJ30608.1 - 0.018 14.4 0.0 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 MutS domain V AAA_18 PF13238.1 OAJ30608.1 - 0.02 15.1 0.1 2.1 8.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain DUF287 PF03384.9 OAJ30608.1 - 0.035 14.2 0.3 0.16 12.1 0.1 2.2 2 0 0 2 2 1 0 Drosophila protein of unknown function, DUF287 cobW PF02492.14 OAJ30608.1 - 0.051 13.0 0.1 8.4 5.7 0.0 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 OAJ30608.1 - 0.098 12.4 4.6 0.76 9.5 0.0 3.2 4 0 0 4 4 3 0 Dynamin family Arch_ATPase PF01637.13 OAJ30608.1 - 0.16 11.6 3.8 6.1 6.4 0.0 3.2 4 0 0 4 4 3 0 Archaeal ATPase DUF1746 PF08508.5 OAJ30609.1 - 3.4e-12 46.3 4.4 2.8e-11 43.3 3.0 2.1 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) 2OG-FeII_Oxy PF03171.15 OAJ30610.1 - 3.7e-21 75.2 0.0 6.2e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 OAJ30610.1 - 3.6e-20 72.6 0.0 6.2e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Ub-Mut7C PF14451.1 OAJ30610.1 - 0.13 11.8 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin zf-H2C2_2 PF13465.1 OAJ30612.1 - 5.9e-08 32.6 0.3 5.9e-08 32.6 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ30612.1 - 5e-05 23.4 13.3 0.0002 21.4 0.6 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ30612.1 - 0.00011 22.2 1.0 0.00011 22.2 0.7 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 OAJ30612.1 - 0.059 13.3 3.8 0.12 12.3 0.3 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger SPRR2 PF14820.1 OAJ30612.1 - 1.8 8.5 10.2 0.8 9.6 3.8 2.4 2 0 0 2 2 2 0 Small proline-rich 2 MRP-L46 PF11788.3 OAJ30613.1 - 6.7e-18 65.3 0.2 2.4e-17 63.5 0.0 2.1 2 1 0 2 2 2 1 39S mitochondrial ribosomal protein L46 Tautomerase PF01361.16 OAJ30613.1 - 0.34 10.5 1.3 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Tautomerase enzyme Response_reg PF00072.19 OAJ30614.1 - 1.6e-06 28.0 0.0 0.00011 22.1 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain Symplekin_C PF12295.3 OAJ30615.1 - 5.9e-52 176.2 0.1 1.9e-51 174.5 0.0 1.9 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 OAJ30615.1 - 2.2e-33 115.6 0.1 4.4e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) HEAT_EZ PF13513.1 OAJ30615.1 - 0.0058 17.0 0.4 0.05 14.1 0.1 2.9 2 0 0 2 2 2 1 HEAT-like repeat zf-CCCH PF00642.19 OAJ30616.1 - 2.1e-22 78.3 33.0 1.1e-06 28.1 0.2 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 OAJ30616.1 - 3.4e-06 26.7 1.5 3.4e-06 26.7 1.1 2.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ30616.1 - 0.0087 15.7 3.8 0.024 14.3 0.3 2.5 2 0 0 2 2 2 1 Zinc knuckle Acetyltransf_1 PF00583.19 OAJ30621.1 - 1.7e-14 53.6 0.0 2.7e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAJ30621.1 - 6.8e-10 39.0 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 OAJ30621.1 - 1.6e-07 31.3 0.0 2.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ30621.1 - 9.7e-07 28.4 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 OAJ30621.1 - 6.5e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 OAJ30621.1 - 8e-06 26.0 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAJ30621.1 - 2.5e-05 24.1 0.0 4.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAJ30621.1 - 0.036 13.9 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CtaG_Cox11 PF04442.9 OAJ30622.1 - 6.9e-52 175.2 0.0 1.3e-51 174.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Ipi1_N PF12333.3 OAJ30623.1 - 1.4e-10 41.0 0.4 4.6e-09 36.1 0.1 3.1 1 1 1 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation CENP-B_dimeris PF09026.5 OAJ30623.1 - 0.026 14.7 1.0 0.056 13.6 0.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sec3_C PF09763.4 OAJ30624.1 - 2.2e-88 297.1 0.0 1.9e-87 294.0 0.0 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 OAJ30624.1 - 1.1e-18 66.8 0.0 2.1e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 OAJ30624.1 - 0.036 12.5 0.2 0.056 11.9 0.2 1.2 1 0 0 1 1 1 0 Vps52 / Sac2 family RCC1 PF00415.13 OAJ30625.1 - 5.3e-23 80.9 12.0 0.00044 20.3 0.3 8.5 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ30625.1 - 6.3e-12 44.7 21.0 6.4e-08 32.0 1.2 6.7 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Abhydrolase_5 PF12695.2 OAJ30626.1 - 2.7e-06 27.2 5.6 2.2e-05 24.2 3.8 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ30626.1 - 9.2e-05 22.4 1.5 0.00023 21.1 0.9 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 OAJ30626.1 - 0.0031 16.8 0.0 0.006 15.8 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 OAJ30626.1 - 0.093 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 OAJ30626.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 OAJ30626.1 - 0.2 11.1 2.6 0.6 9.6 1.8 1.8 1 1 0 1 1 1 0 PGAP1-like protein SAP PF02037.22 OAJ30627.1 - 5e-10 38.6 0.4 8.4e-10 37.9 0.3 1.4 1 0 0 1 1 1 1 SAP domain Pex14_N PF04695.8 OAJ30627.1 - 0.0091 16.0 0.7 0.0091 16.0 0.5 4.0 4 1 0 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region RPA_interact_N PF14766.1 OAJ30627.1 - 0.13 11.7 0.1 0.25 10.8 0.1 1.5 1 0 0 1 1 1 0 Replication protein A interacting N-terminal Lactamase_B PF00753.22 OAJ30628.1 - 5.4e-22 78.3 2.6 8.1e-22 77.8 1.8 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily ADH_zinc_N_2 PF13602.1 OAJ30629.1 - 7.2e-09 36.6 0.0 3.1e-08 34.5 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ30629.1 - 0.00015 21.4 0.4 0.00029 20.5 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ30629.1 - 0.011 15.3 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF4137 PF13593.1 OAJ30629.1 - 1.5 7.8 0.1 2.5 7.1 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) GAS PF13851.1 OAJ30630.1 - 0.05 12.7 0.3 0.1 11.8 0.2 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HALZ PF02183.13 OAJ30630.1 - 0.093 12.4 0.5 0.22 11.2 0.4 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper TPT PF03151.11 OAJ30632.1 - 1.4e-31 109.2 3.8 1.4e-31 109.2 2.7 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 OAJ30632.1 - 8.9e-11 41.9 19.2 1.7e-05 24.8 3.3 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 OAJ30632.1 - 0.00074 18.5 13.5 0.0028 16.6 9.4 1.9 1 1 0 1 1 1 1 UAA transporter family Bd3614_N PF14442.1 OAJ30632.1 - 0.017 15.0 1.3 0.045 13.7 0.9 1.7 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal MFS_Mycoplasma PF07672.8 OAJ30632.1 - 0.06 12.5 0.2 0.06 12.5 0.1 2.5 3 0 0 3 3 3 0 Mycoplasma MFS transporter EmrE PF13536.1 OAJ30632.1 - 8.4 6.6 19.9 2.6 8.2 3.4 2.8 2 2 0 2 2 2 0 Multidrug resistance efflux transporter Thiolase_N PF00108.18 OAJ30633.1 - 3.1e-96 321.4 2.6 4.8e-96 320.7 1.8 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAJ30633.1 - 2.9e-43 146.1 1.6 4.3e-42 142.4 0.4 2.5 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 OAJ30633.1 - 4.5e-06 26.3 2.9 3.7e-05 23.3 0.8 2.5 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SRPRB PF09439.5 OAJ30635.1 - 9.5e-10 37.9 0.0 2e-09 36.9 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 OAJ30635.1 - 0.0012 19.2 0.0 0.0026 18.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein DUF374 PF04028.8 OAJ30635.1 - 0.0029 16.8 0.6 0.0076 15.4 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF374) MMR_HSR1 PF01926.18 OAJ30635.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 OAJ30635.1 - 0.051 12.7 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 OAJ30635.1 - 0.06 12.8 0.3 0.06 12.8 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain G-alpha PF00503.15 OAJ30635.1 - 0.067 11.8 0.1 0.13 10.8 0.1 1.4 1 0 0 1 1 1 0 G-protein alpha subunit SMC_N PF02463.14 OAJ30635.1 - 0.077 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 OAJ30635.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain EAP30 PF04157.11 OAJ30636.1 - 6.7e-42 143.1 0.0 1.2e-41 142.3 0.0 1.4 1 1 0 1 1 1 1 EAP30/Vps36 family QLQ PF08880.6 OAJ30636.1 - 0.11 11.9 0.8 0.26 10.7 0.3 1.9 2 0 0 2 2 2 0 QLQ Cellulase PF00150.13 OAJ30637.1 - 5.6e-07 29.0 2.0 1.2e-06 27.9 1.4 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.13 OAJ30638.1 - 3.3e-06 26.5 1.4 5.9e-06 25.6 1.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ribosomal_L30_N PF08079.7 OAJ30639.1 - 1.1e-25 89.3 17.5 2.3e-25 88.4 12.1 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 OAJ30639.1 - 1.3e-17 63.0 0.8 3.1e-17 61.8 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Rep_Org_C PF06926.6 OAJ30639.1 - 0.1 12.7 0.5 0.19 11.8 0.4 1.4 1 0 0 1 1 1 0 Putative replisome organiser protein C-terminus Ribosomal_L16 PF00252.13 OAJ30640.1 - 3.2e-30 104.6 0.0 4e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RNase_PH PF01138.16 OAJ30641.1 - 6.2e-07 29.7 1.7 1.1e-06 29.0 1.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 3HCDH_N PF02737.13 OAJ30642.1 - 6.9e-45 152.9 0.3 3.6e-44 150.5 0.2 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 OAJ30642.1 - 3.1e-35 120.4 0.0 6.6e-35 119.3 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF2680 PF10925.3 OAJ30642.1 - 0.052 13.4 0.2 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) F420_oxidored PF03807.12 OAJ30642.1 - 0.21 12.0 1.6 0.41 11.0 0.4 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_1 PF00667.15 OAJ30643.1 - 1.8e-51 174.7 0.0 2.6e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 OAJ30643.1 - 1.1e-06 29.2 0.0 6.6e-06 26.6 0.0 2.2 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.13 OAJ30643.1 - 0.00016 21.6 0.0 0.00048 20.0 0.0 1.8 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase FAD_binding_6 PF00970.19 OAJ30643.1 - 0.17 12.0 0.0 0.53 10.4 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain AP_endonuc_2 PF01261.19 OAJ30644.1 - 9.3e-11 41.4 0.0 0.00043 19.6 0.0 2.9 2 1 0 2 2 2 2 Xylose isomerase-like TIM barrel Proteasome PF00227.21 OAJ30645.1 - 2.6e-58 196.4 0.0 3.6e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAJ30645.1 - 8.3e-14 50.6 0.2 1.5e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature LSM PF01423.17 OAJ30646.1 - 2.5e-12 46.1 0.1 3.3e-12 45.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 OAJ30646.1 - 0.094 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Aminotran_1_2 PF00155.16 OAJ30647.1 - 5.6e-44 150.5 0.0 5.6e-43 147.2 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAJ30647.1 - 0.0025 17.0 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 OAJ30647.1 - 0.034 12.8 0.0 0.055 12.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V SAMP PF05924.6 OAJ30647.1 - 0.059 12.5 0.1 0.14 11.3 0.1 1.7 1 0 0 1 1 1 0 SAMP Motif Macoilin PF09726.4 OAJ30647.1 - 8.5 4.5 6.8 12 4.0 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein zf-C2H2 PF00096.21 OAJ30648.1 - 7.4e-06 25.9 17.7 5.1e-05 23.3 1.3 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAJ30648.1 - 4.4e-05 23.5 6.7 5.8e-05 23.1 1.4 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 OAJ30648.1 - 0.0026 17.9 0.9 0.0026 17.9 0.6 4.0 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAJ30648.1 - 0.034 14.3 0.1 0.034 14.3 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAJ30648.1 - 0.043 14.0 0.1 0.043 14.0 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 OAJ30648.1 - 1 9.0 3.3 0.8 9.4 1.0 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type MULE PF10551.4 OAJ30651.1 - 5.1e-08 32.9 0.2 2.5e-07 30.7 0.0 2.3 2 1 1 3 3 3 1 MULE transposase domain SWIM PF04434.12 OAJ30651.1 - 3.7e-05 23.1 1.9 0.00012 21.4 1.3 1.9 1 0 0 1 1 1 1 SWIM zinc finger DDE_Tnp_IS240 PF13610.1 OAJ30651.1 - 0.042 13.8 0.0 10 6.1 0.0 3.0 3 0 0 3 3 3 0 DDE domain Sporozoite_P67 PF05642.6 OAJ30651.1 - 0.27 9.0 3.3 0.41 8.4 2.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAP1 PF07218.6 OAJ30651.1 - 3.8 5.4 4.9 5.7 4.9 3.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_M16_C PF05193.16 OAJ30652.1 - 6e-24 84.7 0.0 1.2e-15 57.6 0.0 2.9 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 OAJ30652.1 - 1e-07 31.7 0.0 8.8e-07 28.7 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) PYRIN PF02758.11 OAJ30652.1 - 0.042 13.5 0.1 0.53 10.0 0.1 2.7 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain DUF1949 PF09186.6 OAJ30652.1 - 0.084 12.4 0.1 0.91 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) Chromo PF00385.19 OAJ30654.1 - 1.9e-06 27.4 0.6 3.3e-06 26.6 0.4 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Nucleoplasmin PF03066.10 OAJ30654.1 - 0.009 15.5 16.6 1.1 8.7 1.0 4.2 4 0 0 4 4 4 3 Nucleoplasmin ST7 PF04184.7 OAJ30654.1 - 4.5 5.3 0.6 6.8 4.7 0.5 1.1 1 0 0 1 1 1 0 ST7 protein Macoilin PF09726.4 OAJ30655.1 - 0.063 11.5 6.8 0.075 11.3 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein CDC45 PF02724.9 OAJ30655.1 - 0.35 8.8 5.6 0.46 8.4 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 OAJ30655.1 - 0.41 9.7 7.8 0.54 9.3 5.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF755 PF05501.6 OAJ30655.1 - 2.5 8.1 27.5 1.1 9.3 16.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Oxidored_q6 PF01058.17 OAJ30657.1 - 8.6e-23 80.3 0.1 1.3e-22 79.7 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DUF1213 PF06740.7 OAJ30658.1 - 0.013 15.5 1.8 0.039 14.0 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1213) DUF605 PF04652.11 OAJ30658.1 - 5.4 6.3 21.3 11 5.3 14.8 1.5 1 0 0 1 1 1 0 Vta1 like Nup88 PF10168.4 OAJ30659.1 - 2.8e-06 25.5 5.7 0.18 9.6 0.0 4.3 5 0 0 5 5 5 3 Nuclear pore component AATF-Che1 PF13339.1 OAJ30659.1 - 0.1 12.7 1.3 8.1 6.6 0.2 2.7 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor SlyX PF04102.7 OAJ30659.1 - 2.9 8.3 9.9 11 6.4 0.4 3.6 4 0 0 4 4 4 0 SlyX EAP30 PF04157.11 OAJ30659.1 - 5.7 6.0 9.2 1.7 7.7 0.1 2.6 3 0 0 3 3 3 0 EAP30/Vps36 family OPT PF03169.10 OAJ30660.1 - 2.1e-188 627.6 54.1 2.4e-188 627.4 37.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pkinase PF00069.20 OAJ30661.1 - 5.1e-63 212.6 0.0 1.2e-62 211.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ30661.1 - 3.8e-33 114.6 0.0 5.5e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ30661.1 - 3.3e-07 29.5 0.0 5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ30661.1 - 0.00029 20.6 0.2 0.00075 19.2 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ30661.1 - 0.0047 16.0 0.0 0.0092 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OPT PF03169.10 OAJ30662.1 - 5.1e-188 626.4 56.3 5.8e-188 626.2 39.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Oxidored_FMN PF00724.15 OAJ30663.1 - 0.0028 16.7 0.0 0.0038 16.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NUDIX PF00293.23 OAJ30664.1 - 4.1e-15 55.6 0.0 7.2e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 OAJ30664.1 - 8.3e-11 42.1 1.8 3.9e-10 39.9 1.2 2.2 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Lipase_3 PF01764.20 OAJ30665.1 - 4.1e-13 49.1 0.0 6.9e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 OAJ30665.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 OAJ30665.1 - 0.049 13.3 0.0 0.12 12.0 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family TMEM171 PF15471.1 OAJ30665.1 - 0.094 11.4 2.9 10 4.7 2.4 2.2 2 0 0 2 2 2 0 Transmembrane protein family 171 DUF2974 PF11187.3 OAJ30665.1 - 0.14 11.5 0.0 0.34 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Strabismus PF06638.6 OAJ30665.1 - 0.93 7.7 2.6 1.4 7.1 1.8 1.2 1 0 0 1 1 1 0 Strabismus protein SKN1 PF03935.10 OAJ30667.1 - 1e-19 70.1 0.0 1.1e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF4015 PF13200.1 OAJ30667.1 - 0.042 12.7 0.3 0.31 9.9 0.2 1.9 1 1 0 1 1 1 0 Putative glycosyl hydrolase domain SKN1 PF03935.10 OAJ30668.1 - 3.3e-112 375.2 1.5 8.4e-75 251.8 0.7 2.1 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.10 OAJ30669.1 - 3.8e-65 219.9 16.2 6.8e-65 219.1 11.2 1.4 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) GST_C_3 PF14497.1 OAJ30670.1 - 0.0029 18.0 0.0 0.0063 16.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom22 PF04281.8 OAJ30672.1 - 5.3e-38 129.6 4.6 9.2e-35 119.1 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial import receptor subunit Tom22 Shadoo PF14999.1 OAJ30672.1 - 0.013 15.3 5.2 0.021 14.6 3.6 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Bindin PF02084.10 OAJ30672.1 - 0.14 12.2 4.6 0.23 11.4 1.2 2.0 2 0 0 2 2 2 0 Bindin Daxx PF03344.10 OAJ30672.1 - 2.2 6.6 8.8 3 6.1 6.1 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 OAJ30672.1 - 2.6 5.8 10.9 3.1 5.6 7.5 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 OAJ30672.1 - 5.8 6.5 10.7 8.9 5.9 7.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.1 OAJ30672.1 - 6.1 7.2 12.3 1.4 9.2 4.8 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Yippee-Mis18 PF03226.9 OAJ30673.1 - 1.8e-11 43.9 0.0 4.4e-11 42.6 0.0 1.7 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SET PF00856.23 OAJ30674.1 - 1.7e-17 64.2 0.1 1.7e-17 64.2 0.1 4.3 3 2 0 3 3 3 1 SET domain PHD PF00628.24 OAJ30675.1 - 1.5e-05 24.5 19.2 2.5e-05 23.8 13.3 1.4 1 0 0 1 1 1 1 PHD-finger Ribosomal_L6e PF01159.14 OAJ30677.1 - 7.3e-34 116.2 0.2 7.3e-34 116.2 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 OAJ30677.1 - 0.00076 19.3 2.3 0.00076 19.3 1.6 2.1 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain ThiF PF00899.16 OAJ30680.1 - 1.1e-39 135.3 0.0 5.6e-39 133.0 0.0 1.9 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 OAJ30680.1 - 2.8e-24 84.4 0.6 6.5e-24 83.2 0.4 1.7 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 OAJ30680.1 - 8e-23 80.0 0.0 1.3e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 OAJ30680.1 - 1.5e-18 65.8 1.6 3.1e-18 64.8 1.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 OAJ30680.1 - 0.00093 19.3 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 OAJ30680.1 - 0.0054 16.3 0.6 0.016 14.7 0.0 1.9 2 0 0 2 2 2 1 MoeZ/MoeB domain DAO PF01266.19 OAJ30680.1 - 0.12 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 OAJ30680.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Ecm33 PF12454.3 OAJ30680.1 - 0.27 11.1 2.3 0.51 10.2 1.6 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein zf-Tim10_DDP PF02953.10 OAJ30681.1 - 5.1e-23 80.1 0.8 6.2e-23 79.8 0.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger QCR10 PF09796.4 OAJ30682.1 - 1.2e-14 53.6 0.5 1.8e-14 53.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 OAJ30682.1 - 0.0077 15.9 0.3 0.014 15.0 0.2 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Rep_fac_C PF08542.6 OAJ30683.1 - 4.8e-19 68.1 0.0 9.8e-19 67.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 OAJ30683.1 - 3.1e-12 46.8 0.0 6.1e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 OAJ30683.1 - 1.8e-11 43.9 0.0 7.5e-10 38.7 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 OAJ30683.1 - 1e-07 32.1 0.1 2.5e-06 27.6 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.6 OAJ30683.1 - 3.3e-06 26.7 0.0 5.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 OAJ30683.1 - 4.5e-06 25.6 0.0 0.00085 18.1 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 OAJ30683.1 - 7.2e-06 25.9 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ30683.1 - 1.3e-05 25.3 0.1 0.0036 17.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 OAJ30683.1 - 4.2e-05 23.1 0.0 0.02 14.3 0.0 2.7 1 1 2 3 3 3 1 AAA-like domain RuvB_N PF05496.7 OAJ30683.1 - 8.7e-05 21.6 0.0 0.00018 20.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus ArgK PF03308.11 OAJ30683.1 - 0.00065 18.5 0.0 0.0014 17.4 0.0 1.6 1 0 0 1 1 1 1 ArgK protein NTPase_1 PF03266.10 OAJ30683.1 - 0.0025 17.5 0.0 0.039 13.6 0.0 2.3 1 1 1 2 2 2 1 NTPase Viral_helicase1 PF01443.13 OAJ30683.1 - 0.0026 17.3 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 OAJ30683.1 - 0.0026 17.4 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_31 PF13614.1 OAJ30683.1 - 0.0046 16.9 0.0 0.011 15.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain FtsK_SpoIIIE PF01580.13 OAJ30683.1 - 0.0053 16.2 0.0 0.015 14.7 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family Mg_chelatase PF01078.16 OAJ30683.1 - 0.013 14.6 0.0 0.1 11.7 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 OAJ30683.1 - 0.014 14.9 0.1 0.069 12.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 OAJ30683.1 - 0.016 14.4 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MipZ PF09140.6 OAJ30683.1 - 0.026 13.6 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ SRP54 PF00448.17 OAJ30683.1 - 0.031 13.7 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.9 OAJ30683.1 - 0.031 13.9 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 OAJ30683.1 - 0.044 12.7 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.24 OAJ30683.1 - 0.052 13.0 0.1 0.33 10.4 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase MobB PF03205.9 OAJ30683.1 - 0.055 13.1 0.1 0.28 10.8 0.0 2.0 1 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 OAJ30683.1 - 0.07 12.5 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SNF2_N PF00176.18 OAJ30684.1 - 2.7e-54 183.9 0.0 2.7e-54 183.9 0.0 3.0 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ30684.1 - 1.9e-13 50.0 0.0 1e-12 47.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.19 OAJ30684.1 - 3e-09 36.3 0.2 0.00043 19.8 0.0 3.2 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 OAJ30684.1 - 9e-06 25.2 6.7 0.016 14.9 0.1 2.8 2 0 0 2 2 2 2 PHD-finger RRM_1 PF00076.17 OAJ30685.1 - 3.4e-16 58.6 0.0 4.7e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ30685.1 - 9.8e-13 47.8 0.0 1.5e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ30685.1 - 9.3e-09 35.0 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ30685.1 - 0.021 14.6 0.3 0.042 13.7 0.2 1.6 1 1 0 1 1 1 0 RNA binding motif DUF3227 PF11537.3 OAJ30685.1 - 0.1 12.7 0.3 0.18 11.9 0.1 1.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3227) Mito_carr PF00153.22 OAJ30686.1 - 5.2e-38 128.6 5.9 1.1e-15 57.0 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein RAP1 PF07218.6 OAJ30686.1 - 1.3 7.0 4.3 1.7 6.6 3.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MoaE PF02391.12 OAJ30687.1 - 5.8e-27 93.8 0.0 1.9e-26 92.1 0.0 1.8 1 1 0 1 1 1 1 MoaE protein TOM13 PF08219.6 OAJ30688.1 - 8.6e-11 41.4 1.8 2.2e-10 40.1 1.1 1.9 1 1 0 1 1 1 1 Outer membrane protein TOM13 LAT PF15234.1 OAJ30688.1 - 0.0054 16.2 1.2 0.0063 16.0 0.8 1.3 1 0 0 1 1 1 1 Linker for activation of T-cells CENP-B_dimeris PF09026.5 OAJ30688.1 - 0.06 13.5 10.5 0.2 11.9 7.5 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nop14 PF04147.7 OAJ30688.1 - 0.084 10.7 7.0 0.092 10.6 4.9 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 OAJ30688.1 - 0.15 11.2 7.2 0.19 10.9 5.0 1.1 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.8 OAJ30688.1 - 0.26 11.1 4.6 0.35 10.6 3.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleoplasmin PF03066.10 OAJ30688.1 - 0.37 10.2 7.9 0.51 9.8 5.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin EBV-NA3 PF05009.7 OAJ30688.1 - 0.91 8.7 3.8 1.2 8.3 2.6 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Sigma70_ner PF04546.8 OAJ30688.1 - 2.1 7.9 6.7 2.6 7.6 4.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 OAJ30688.1 - 2.1 7.4 6.4 2.7 7.0 4.5 1.3 1 0 0 1 1 1 0 Myc amino-terminal region BTV_NS2 PF04514.7 OAJ30688.1 - 4.3 6.1 8.4 5.6 5.7 5.9 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PX PF00787.19 OAJ30689.1 - 1.7e-19 69.6 0.0 3.1e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 PX domain Cytomega_UL20A PF05984.7 OAJ30691.1 - 0.0079 16.3 1.4 0.47 10.6 0.1 2.3 2 0 0 2 2 2 2 Cytomegalovirus UL20A protein TRAUB PF08164.7 OAJ30691.1 - 0.44 10.6 3.9 1.5 9.0 2.7 1.9 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal ApbA_C PF08546.6 OAJ30692.1 - 6.8e-19 68.0 0.0 2.6e-09 37.1 0.0 3.2 4 1 0 4 4 4 2 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 OAJ30692.1 - 2.2e-16 59.6 0.0 9.8e-12 44.5 0.0 2.5 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Syd PF07348.7 OAJ30693.1 - 0.0072 15.6 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Syd protein (SUKH-2) DUF1399 PF07173.7 OAJ30694.1 - 2.2e-15 57.1 1.0 1.5e-13 51.1 0.1 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1399) DUF4301 PF14134.1 OAJ30694.1 - 0.18 10.3 0.0 0.27 9.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) Acyl-CoA_ox_N PF14749.1 OAJ30695.1 - 2.9e-19 69.6 0.1 4.5e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 OAJ30695.1 - 5.3e-05 22.6 0.0 0.00011 21.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain UDPGT PF00201.13 OAJ30696.1 - 9e-15 54.1 0.1 2e-14 53.0 0.1 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase RAP-1 PF03085.10 OAJ30697.1 - 0.34 10.2 5.1 0.61 9.3 3.6 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) F-box-like PF12937.2 OAJ30698.1 - 0.026 14.2 1.0 0.072 12.8 0.1 2.2 2 0 0 2 2 2 0 F-box-like Sec7 PF01369.15 OAJ30699.1 - 2.2e-61 206.8 0.0 4.3e-61 205.9 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 OAJ30699.1 - 0.0001 21.7 4.9 0.1 11.9 0.8 4.0 2 1 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal PolyA_pol PF01743.15 OAJ30700.1 - 6.5e-23 81.3 0.0 1.2e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 OAJ30700.1 - 0.0021 17.5 0.1 0.0052 16.3 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A GWT1 PF06423.7 OAJ30701.1 - 4.3e-32 111.0 0.0 2.4e-21 76.2 0.0 2.7 2 0 0 2 2 2 2 GWT1 Med5 PF08689.5 OAJ30702.1 - 8.7e-30 103.1 0.0 1.1e-28 99.5 0.0 2.0 1 1 0 1 1 1 1 Mediator complex subunit Med5 AMP-binding PF00501.23 OAJ30702.1 - 2.5e-15 55.8 1.1 2.2e-14 52.7 0.8 2.0 1 1 0 1 1 1 1 AMP-binding enzyme NUDE_C PF04880.8 OAJ30703.1 - 7.9e-10 39.3 16.5 7.9e-10 39.3 11.5 3.4 2 1 1 3 3 2 1 NUDE protein, C-terminal conserved region DUF3584 PF12128.3 OAJ30703.1 - 7.7e-05 20.2 15.3 0.00011 19.7 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 OAJ30703.1 - 0.0013 18.4 23.4 0.022 14.5 2.3 2.5 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein DivIC PF04977.10 OAJ30703.1 - 0.0021 17.4 14.9 0.17 11.3 0.4 3.7 2 1 1 3 3 3 2 Septum formation initiator Filament PF00038.16 OAJ30703.1 - 0.0032 16.9 7.6 0.0032 16.9 5.3 2.3 1 1 1 2 2 2 1 Intermediate filament protein DUF948 PF06103.6 OAJ30703.1 - 0.0053 16.6 7.0 0.74 9.7 0.5 3.6 3 1 1 4 4 4 2 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.6 OAJ30703.1 - 0.011 16.1 16.2 0.087 13.2 3.4 3.2 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Prefoldin_2 PF01920.15 OAJ30703.1 - 0.015 15.0 23.9 0.12 12.1 7.6 3.1 2 1 1 3 3 3 0 Prefoldin subunit Lzipper-MIP1 PF14389.1 OAJ30703.1 - 0.026 14.6 6.6 2.1 8.4 0.2 3.2 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Laminin_II PF06009.7 OAJ30703.1 - 0.036 13.8 17.6 0.025 14.3 3.5 3.5 2 1 2 4 4 4 0 Laminin Domain II Tox-PLDMTX PF15645.1 OAJ30703.1 - 0.036 14.0 1.3 0.077 13.0 0.9 1.5 1 0 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold IncA PF04156.9 OAJ30703.1 - 0.049 13.2 20.5 0.052 13.1 7.0 2.5 1 1 1 2 2 2 0 IncA protein DUF2935 PF11155.3 OAJ30703.1 - 0.063 13.3 4.2 3.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) AAA_27 PF13514.1 OAJ30703.1 - 0.086 10.5 18.0 0.086 10.5 2.3 2.0 1 1 1 2 2 2 0 AAA domain DivIVA PF05103.8 OAJ30703.1 - 0.096 12.7 14.7 0.24 11.4 0.2 3.2 3 1 0 3 3 3 0 DivIVA protein DUF904 PF06005.7 OAJ30703.1 - 0.16 12.2 25.8 0.028 14.7 3.7 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF904) DUF3452 PF11934.3 OAJ30703.1 - 0.52 9.6 2.8 3.6 6.9 1.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) NPV_P10 PF05531.7 OAJ30703.1 - 0.64 10.2 4.9 4.3 7.6 0.6 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 OAJ30703.1 - 0.81 8.8 15.8 0.015 14.5 2.9 2.6 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 OAJ30703.1 - 0.84 9.4 6.2 0.38 10.5 1.3 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.3 OAJ30703.1 - 1 9.2 20.0 0.17 11.6 2.8 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Viral_P18 PF04521.8 OAJ30703.1 - 1.5 8.2 10.4 4.1 6.8 0.2 3.4 2 1 1 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein TBPIP PF07106.8 OAJ30703.1 - 1.7 8.1 21.4 1.2 8.6 6.8 3.1 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tweety PF04906.8 OAJ30703.1 - 2.8 6.2 3.6 1.2 7.4 0.4 1.9 2 1 0 2 2 2 0 Tweety CCDC84 PF14968.1 OAJ30703.1 - 3.7 6.9 10.4 1.2 8.5 4.4 1.9 1 1 1 2 2 2 0 Coiled coil protein 84 DUF972 PF06156.8 OAJ30703.1 - 3.8 7.8 20.7 1.4 9.3 1.8 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) TMPIT PF07851.8 OAJ30703.1 - 5.8 5.8 14.6 4 6.4 3.7 2.1 1 1 1 2 2 2 0 TMPIT-like protein ADIP PF11559.3 OAJ30703.1 - 6.4 6.6 20.1 1.1 9.1 7.5 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 OAJ30703.1 - 6.8 5.5 13.8 3.6 6.4 0.5 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 OAJ30703.1 - 6.9 6.7 19.4 2.3 8.2 1.2 4.1 3 1 1 4 4 4 0 bZIP transcription factor HALZ PF02183.13 OAJ30703.1 - 6.9 6.4 8.9 1.3 8.7 0.7 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper COG2 PF06148.6 OAJ30703.1 - 7.6 6.4 14.3 0.31 10.8 1.8 3.0 3 1 1 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_GPO PF05929.6 OAJ30703.1 - 8.2 5.5 10.5 3.4 6.8 4.6 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Spc7 PF08317.6 OAJ30703.1 - 9.8 4.7 18.9 4 5.9 8.0 2.3 1 1 0 2 2 2 0 Spc7 kinetochore protein FMN_dh PF01070.13 OAJ30704.1 - 4.9e-108 361.1 0.2 2.5e-97 325.9 0.0 2.0 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.12 OAJ30704.1 - 3.8e-05 22.7 0.1 6.1e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 OAJ30704.1 - 0.00023 20.1 1.4 0.00057 18.8 0.7 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 OAJ30704.1 - 0.0062 15.6 0.8 1.4 7.8 0.0 2.4 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG TGT PF01702.13 OAJ30704.1 - 0.05 12.8 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Queuine tRNA-ribosyltransferase UreF PF01730.11 OAJ30705.1 - 4.9e-09 36.4 4.1 9.9e-08 32.2 2.8 2.4 1 1 0 1 1 1 1 UreF Peptidase_M20 PF01546.23 OAJ30706.1 - 6.2e-23 81.2 0.0 1e-22 80.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 OAJ30706.1 - 1.5e-10 40.8 1.2 1.5e-09 37.6 0.8 2.4 1 1 0 1 1 1 1 Peptidase dimerisation domain ICA69 PF04629.9 OAJ30706.1 - 0.029 14.3 0.2 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Islet cell autoantigen ICA69, C-terminal domain ADH_N PF08240.7 OAJ30707.1 - 1.3e-25 89.2 3.4 1.3e-25 89.2 2.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ30707.1 - 3.8e-13 49.1 0.2 6e-13 48.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ30707.1 - 5.1e-05 24.1 0.0 9.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 OAJ30707.1 - 0.00048 19.3 0.1 0.0011 18.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 OAJ30707.1 - 0.0079 15.8 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 OAJ30707.1 - 0.016 15.0 0.2 0.036 13.9 0.1 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Oxidored_nitro PF00148.14 OAJ30707.1 - 0.016 13.8 0.0 0.028 13.0 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase ELFV_dehydrog PF00208.16 OAJ30707.1 - 0.031 13.8 0.1 0.059 12.9 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.1 OAJ30707.1 - 0.053 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Pro_CA PF00484.14 OAJ30708.1 - 8.6e-39 132.9 0.0 1.2e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_1 PF00561.15 OAJ30708.1 - 0.0072 15.9 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2922 PF11148.3 OAJ30708.1 - 0.06 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) Sda PF08970.5 OAJ30708.1 - 0.079 12.4 0.2 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Sporulation inhibitor A XPG_N PF00752.12 OAJ30709.1 - 8.2e-35 119.1 0.0 1.5e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 OAJ30709.1 - 5.2e-30 103.3 0.0 1.1e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 OAJ30709.1 - 1.1e-07 32.0 0.0 2.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 OAJ30709.1 - 0.024 14.7 0.0 0.064 13.4 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_2 PF12826.2 OAJ30709.1 - 0.095 12.6 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Transposase_20 PF02371.11 OAJ30709.1 - 0.097 12.7 0.0 0.65 10.1 0.0 2.2 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family MFS_1 PF07690.11 OAJ30710.1 - 1.6e-40 138.9 46.3 2.4e-40 138.3 29.9 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAJ30710.1 - 3.7e-17 61.7 10.6 3.7e-17 61.7 7.3 1.7 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 OAJ30710.1 - 1.9e-12 46.4 13.4 1.9e-12 46.4 9.3 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter bZIP_2 PF07716.10 OAJ30711.1 - 1.6e-08 34.2 12.7 1.6e-08 34.2 8.8 3.3 2 1 0 2 2 1 1 Basic region leucine zipper Spore_coat_CotO PF14153.1 OAJ30711.1 - 8.5e-05 22.0 10.4 8.5e-05 22.0 7.2 2.0 2 0 0 2 2 2 1 Spore coat protein CotO Ycf1 PF05758.7 OAJ30711.1 - 0.00034 18.5 4.5 0.00056 17.7 3.1 1.2 1 0 0 1 1 1 1 Ycf1 bZIP_1 PF00170.16 OAJ30711.1 - 0.0023 17.8 10.8 0.0023 17.8 7.5 2.4 2 1 0 2 2 1 1 bZIP transcription factor zf-DHHC PF01529.15 OAJ30711.1 - 0.016 14.6 0.2 0.029 13.7 0.1 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase Zip PF02535.17 OAJ30711.1 - 0.016 14.2 2.6 0.028 13.4 1.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SPX PF03105.14 OAJ30711.1 - 0.017 14.9 12.6 0.045 13.5 5.4 2.3 2 0 0 2 2 2 0 SPX domain FimP PF09766.4 OAJ30711.1 - 0.16 10.9 29.2 0.39 9.7 20.2 1.6 1 0 0 1 1 1 0 Fms-interacting protein Plasmodium_Vir PF05795.6 OAJ30711.1 - 0.19 10.8 1.6 0.38 9.8 1.1 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PAT1 PF09770.4 OAJ30711.1 - 0.31 9.2 54.9 0.64 8.1 38.0 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.11 OAJ30711.1 - 0.4 9.1 0.3 0.57 8.7 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CDK5_activator PF03261.10 OAJ30711.1 - 2.1 7.6 16.8 3.5 6.8 11.6 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Band_3_cyto PF07565.8 OAJ30711.1 - 2.7 7.4 19.7 5.4 6.4 13.6 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3373 PF11853.3 OAJ30711.1 - 7.3 4.9 14.9 14 4.0 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) MFS_1 PF07690.11 OAJ30712.1 - 1.7e-17 63.2 31.4 1.7e-17 63.2 21.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 OAJ30712.1 - 1.6e-14 53.7 7.0 1.6e-14 53.7 4.9 2.8 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 MerC PF03203.9 OAJ30712.1 - 0.027 14.8 1.8 0.027 14.8 1.2 3.1 3 2 1 4 4 4 0 MerC mercury resistance protein DUF2435 PF10363.4 OAJ30713.1 - 1.2e-24 86.0 0.3 1.5e-23 82.5 0.0 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 OAJ30713.1 - 0.046 13.2 0.0 0.15 11.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) TPR_11 PF13414.1 OAJ30714.1 - 8.6e-12 44.5 1.1 8.3e-07 28.5 0.0 4.8 3 1 1 4 4 4 2 TPR repeat TPR_17 PF13431.1 OAJ30714.1 - 3.1e-05 23.8 0.5 0.77 10.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ30714.1 - 6.4e-05 23.5 5.6 0.00088 19.8 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ30714.1 - 0.00018 21.1 15.2 0.18 11.8 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ30714.1 - 0.00026 20.8 3.7 0.13 12.1 0.0 4.9 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ30714.1 - 0.0022 17.5 1.0 2.2 8.0 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ30714.1 - 0.011 15.6 8.2 7.4 6.6 0.3 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ30714.1 - 0.02 15.4 0.1 0.02 15.4 0.1 6.6 6 2 2 8 8 8 0 Tetratricopeptide repeat Proteasome PF00227.21 OAJ30715.1 - 7.8e-33 113.3 0.0 9.2e-33 113.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Bromodomain PF00439.20 OAJ30717.1 - 1.1e-17 63.6 0.1 2.9e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Peptidase_M1 PF01433.15 OAJ30717.1 - 8e-09 35.0 0.1 0.00077 18.6 0.0 3.9 3 1 0 4 4 4 3 Peptidase family M1 HEAT_2 PF13646.1 OAJ30717.1 - 1.5e-05 25.1 0.6 0.029 14.6 0.0 3.8 4 0 0 4 4 4 2 HEAT repeats Glyco_hydro_31 PF01055.21 OAJ30718.1 - 1.1e-142 475.9 1.2 1.5e-142 475.5 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 OAJ30718.1 - 1.2e-19 69.9 0.0 3.7e-19 68.3 0.0 1.9 2 0 0 2 2 2 1 Galactose mutarotase-like DIOX_N PF14226.1 OAJ30719.1 - 3.3e-09 37.2 0.2 6.7e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAJ30719.1 - 1.4e-07 31.7 0.0 5.8e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily RasGEF PF00617.14 OAJ30720.1 - 1.2e-61 207.6 0.1 1.9e-61 207.1 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 OAJ30720.1 - 4e-25 87.9 0.1 8.8e-25 86.8 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Nop14 PF04147.7 OAJ30720.1 - 0.79 7.5 5.0 1.2 6.9 3.4 1.2 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 OAJ30720.1 - 0.84 8.5 2.5 1.5 7.7 1.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PIF1 PF05970.9 OAJ30722.1 - 1.4e-104 349.9 0.0 1.8e-104 349.5 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ30722.1 - 4.1e-61 205.9 0.4 1.5e-60 204.1 0.1 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 OAJ30722.1 - 4.6e-07 29.6 0.1 8.2e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 OAJ30722.1 - 8.1e-06 23.8 0.0 1.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Helicase AAA_19 PF13245.1 OAJ30722.1 - 0.0059 16.3 0.4 0.019 14.7 0.3 1.8 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 OAJ30722.1 - 0.0067 15.5 0.0 0.015 14.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin UvrD_C_2 PF13538.1 OAJ30722.1 - 0.023 14.8 0.0 0.073 13.2 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain T2SE PF00437.15 OAJ30722.1 - 0.079 11.8 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein SUA5 PF03481.8 OAJ30723.1 - 0.071 13.1 0.1 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative GTP-binding controlling metal-binding GST_C_4 PF14834.1 OAJ30723.1 - 0.078 12.9 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pox_VLTF3 PF04947.9 OAJ30723.1 - 0.087 12.3 0.0 0.094 12.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like RVT_1 PF00078.22 OAJ30724.1 - 2e-11 43.6 0.0 3.5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MethyTransf_Reg PF10119.4 OAJ30724.1 - 0.13 12.7 0.0 0.55 10.7 0.0 2.0 2 0 0 2 2 2 0 Predicted methyltransferase regulatory domain Cnd2 PF05786.9 OAJ30728.1 - 1.3e-133 447.1 19.8 8.6e-81 272.5 1.1 4.2 4 0 0 4 4 4 3 Condensin complex subunit 2 DUF4152 PF13680.1 OAJ30728.1 - 0.00085 18.4 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4152) GCFC PF07842.7 OAJ30729.1 - 1.6e-68 231.0 14.2 2.3e-68 230.5 9.8 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 OAJ30729.1 - 1.7e-08 34.1 0.3 1.7e-08 34.1 0.2 2.3 2 0 0 2 2 2 1 G-patch domain DUF1700 PF08006.6 OAJ30730.1 - 7.1 5.8 6.5 10 5.3 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) TatD_DNase PF01026.16 OAJ30731.1 - 4.2e-49 167.0 0.0 6.4e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase His_Phos_1 PF00300.17 OAJ30732.1 - 4.7e-14 52.7 0.0 2.5e-12 47.1 0.0 2.7 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Pol_alpha_B_N PF08418.5 OAJ30732.1 - 0.13 11.7 4.4 0.28 10.6 3.0 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Fer2_4 PF13510.1 OAJ30733.1 - 3.5e-19 68.3 0.1 9.1e-19 67.0 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 OAJ30733.1 - 1.3e-16 59.5 0.0 1.3e-16 59.5 0.0 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.22 OAJ30733.1 - 3.6e-09 36.2 1.2 1.2e-08 34.5 0.2 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 OAJ30733.1 - 0.015 15.8 0.0 0.038 14.5 0.0 1.7 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4 PF00037.22 OAJ30733.1 - 0.024 14.2 1.4 1.9 8.2 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.1 OAJ30733.1 - 0.079 13.3 2.1 0.2 12.0 1.4 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_19 PF06902.6 OAJ30733.1 - 0.096 12.5 2.4 2 8.3 1.7 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster NDUF_B8 PF05821.6 OAJ30734.1 - 1.5e-09 37.7 0.0 2.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) XPG_N PF00752.12 OAJ30735.1 - 8.5e-29 99.7 0.0 1.6e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 OAJ30735.1 - 1e-26 92.7 0.0 2.4e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 XPG I-region PLA2_B PF01735.13 OAJ30738.1 - 7.4e-138 459.7 1.4 8.8e-138 459.5 1.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Metallophos PF00149.23 OAJ30739.1 - 7.5e-43 146.2 0.9 9.5e-43 145.9 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RPE65 PF03055.10 OAJ30740.1 - 3.9e-103 345.6 0.0 5.3e-103 345.1 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF3812 PF12757.2 OAJ30740.1 - 0.27 11.2 4.2 0.47 10.4 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3812) Syja_N PF02383.13 OAJ30741.1 - 9.1e-89 297.3 0.0 1.4e-88 296.7 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain zf-FCS PF06467.9 OAJ30742.1 - 1.1 8.8 4.5 23 4.7 0.0 2.7 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Pil1 PF13805.1 OAJ30743.1 - 2.3e-05 23.6 3.0 7.6e-05 21.9 2.1 1.9 1 0 0 1 1 1 1 Eisosome component PIL1 FHA PF00498.21 OAJ30744.1 - 3.5e-07 30.2 0.0 6.2e-06 26.2 0.0 2.4 1 1 0 1 1 1 1 FHA domain Gti1_Pac2 PF09729.4 OAJ30745.1 - 1.2e-55 187.9 0.0 2.2e-55 187.0 0.0 1.5 1 0 0 1 1 1 1 Gti1/Pac2 family AMP-binding PF00501.23 OAJ30746.1 - 2.3e-74 250.3 0.0 2.9e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ30746.1 - 1.6e-11 44.9 0.1 4e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 OAJ30747.1 - 7.1e-82 275.0 0.0 9.3e-82 274.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ30747.1 - 8e-08 33.1 0.0 3.5e-07 31.0 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Tubulin PF00091.20 OAJ30748.1 - 2.7e-72 243.1 0.0 4.7e-72 242.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 OAJ30748.1 - 4.3e-49 165.7 0.5 6.7e-49 165.1 0.3 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 OAJ30748.1 - 4.7e-07 29.8 0.1 1.3e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 OAJ30748.1 - 0.00063 19.2 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Pirin PF02678.11 OAJ30749.1 - 1.8e-28 98.5 1.3 2.8e-28 97.9 0.9 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 OAJ30749.1 - 1.4e-06 27.6 1.6 1.3e-05 24.5 0.3 2.4 2 0 0 2 2 2 1 Cupin domain CAML PF14963.1 OAJ30749.1 - 0.076 12.3 0.0 0.14 11.5 0.0 1.4 1 1 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF3337 PF11816.3 OAJ30750.1 - 3.7e-41 141.6 0.0 8e-40 137.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 OAJ30750.1 - 1.1e-31 107.4 23.4 1e-09 37.8 0.1 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 OAJ30750.1 - 0.21 9.6 2.5 4 5.4 0.0 3.0 4 0 0 4 4 4 0 Nucleoporin Nup120/160 Ins_P5_2-kin PF06090.7 OAJ30753.1 - 5.3e-42 143.9 0.0 4.7e-41 140.8 0.0 2.0 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase zf-C2H2 PF00096.21 OAJ30753.1 - 3.6e-11 42.7 7.6 3.7e-05 23.7 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ30753.1 - 1.2e-05 25.3 6.6 0.038 14.3 1.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ30753.1 - 0.00055 20.1 9.3 0.00061 19.9 0.4 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 OAJ30753.1 - 0.095 12.6 1.4 7.5 6.6 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 OAJ30753.1 - 0.87 9.3 3.5 15 5.3 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 OAJ30753.1 - 0.97 9.6 10.0 0.59 10.3 1.2 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF2235 PF09994.4 OAJ30755.1 - 1.4e-62 211.6 0.0 3.2e-62 210.4 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 OAJ30755.1 - 0.023 14.4 0.0 0.084 12.6 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family TauD PF02668.11 OAJ30756.1 - 2.7e-25 89.5 0.0 3.4e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_4 PF01565.18 OAJ30757.1 - 7.4e-22 77.3 3.0 1.5e-21 76.2 2.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAJ30757.1 - 0.0079 16.0 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DCP2 PF05026.8 OAJ30758.1 - 9e-29 99.2 0.1 1.6e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 OAJ30758.1 - 1.7e-13 50.3 0.0 2.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-HIT PF04438.11 OAJ30759.1 - 1.5e-08 34.0 9.2 2.5e-08 33.4 6.4 1.3 1 0 0 1 1 1 1 HIT zinc finger PAP2_3 PF14378.1 OAJ30759.1 - 0.024 14.1 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 PAP2 superfamily ORC5_C PF14630.1 OAJ30760.1 - 7.2e-41 140.4 0.5 2.1e-38 132.3 0.4 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 OAJ30760.1 - 0.12 12.4 6.4 0.078 12.9 0.9 2.9 3 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 OAJ30760.1 - 0.12 12.5 0.0 0.33 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF2012 PF09430.5 OAJ30761.1 - 3e-21 75.5 0.0 6.8e-21 74.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2012) DUF4089 PF13318.1 OAJ30762.1 - 1.8 8.9 6.4 0.81 10.0 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4089) Thioesterase PF00975.15 OAJ30763.1 - 1.1e-09 38.9 0.4 2.5e-09 37.6 0.2 1.7 2 0 0 2 2 2 1 Thioesterase domain DUF1762 PF08574.5 OAJ30764.1 - 0.0022 18.3 9.7 0.0022 18.3 6.7 3.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1762) Cnd1 PF12717.2 OAJ30766.1 - 4.7e-63 212.2 5.5 4.3e-56 189.5 0.1 4.3 3 2 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 OAJ30766.1 - 2.3e-38 131.4 7.3 1.6e-37 128.7 0.0 4.6 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 OAJ30766.1 - 1.6e-09 37.8 1.5 0.017 15.3 0.0 5.6 6 0 0 6 6 6 2 HEAT repeats Adaptin_N PF01602.15 OAJ30766.1 - 2e-08 33.0 1.7 0.012 13.9 0.0 4.6 3 2 1 4 4 4 4 Adaptin N terminal region HEAT PF02985.17 OAJ30766.1 - 4.5e-06 26.3 1.9 1.1 9.5 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 OAJ30766.1 - 0.00031 21.1 4.0 1.2 9.7 0.0 5.3 5 0 0 5 5 5 2 HEAT-like repeat Cnd3 PF12719.2 OAJ30766.1 - 0.00073 18.6 0.8 0.017 14.1 0.1 3.1 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain DUF2435 PF10363.4 OAJ30766.1 - 0.025 14.4 2.8 13 5.7 0.0 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF2435) PqqD PF05402.7 OAJ30766.1 - 0.036 14.0 0.9 1.8 8.6 0.0 3.7 3 1 1 4 4 4 0 Coenzyme PQQ synthesis protein D (PqqD) FAD_binding_2 PF00890.19 OAJ30767.1 - 8.8e-33 113.7 0.0 1.5e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 OAJ30767.1 - 1.3e-21 76.1 0.2 3e-21 74.9 0.1 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF756 PF05506.7 OAJ30767.1 - 0.0069 16.8 0.8 0.014 15.8 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF756) Chorion_2 PF03964.10 OAJ30767.1 - 0.017 15.6 3.3 0.034 14.6 2.3 1.4 1 0 0 1 1 1 0 Chorion family 2 Rgp1 PF08737.5 OAJ30768.1 - 1.9e-71 241.3 0.0 5e-71 239.9 0.0 1.7 1 1 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 OAJ30768.1 - 0.00038 20.2 0.1 0.23 11.2 0.0 3.1 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain MCPVI PF02993.9 OAJ30768.1 - 0.28 11.3 4.7 0.94 9.5 3.3 1.9 1 0 0 1 1 1 0 Minor capsid protein VI DPBB_1 PF03330.13 OAJ30769.1 - 0.00044 20.2 0.6 0.00091 19.1 0.1 1.9 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel SRC-1 PF08832.5 OAJ30769.1 - 0.092 13.5 0.1 0.14 12.9 0.1 1.3 1 0 0 1 1 1 0 Steroid receptor coactivator Cerato-platanin PF07249.7 OAJ30769.1 - 0.1 12.6 0.1 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Cerato-platanin ECR1_N PF14382.1 OAJ30770.1 - 6.1e-06 25.4 0.0 1.7e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 OAJ30770.1 - 0.0053 16.6 0.0 0.12 12.3 0.0 2.6 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 RFC1 PF08519.7 OAJ30771.1 - 4.7e-50 169.3 0.0 1.5e-49 167.7 0.0 1.9 2 0 0 2 2 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 OAJ30771.1 - 3.3e-10 39.9 0.0 7.1e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 OAJ30771.1 - 1.5e-09 38.1 0.0 4.3e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 OAJ30771.1 - 2.7e-07 29.6 0.1 8.3e-06 24.7 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 OAJ30771.1 - 0.00014 22.6 0.1 0.00056 20.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 OAJ30771.1 - 0.00078 19.3 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ30771.1 - 0.00084 19.4 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ30771.1 - 0.00094 19.4 0.1 0.0028 17.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 OAJ30771.1 - 0.0016 18.1 0.0 0.0047 16.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 OAJ30771.1 - 0.0017 18.3 0.0 0.0038 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 OAJ30771.1 - 0.003 16.6 0.0 0.0058 15.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 OAJ30771.1 - 0.0047 16.4 0.3 0.036 13.5 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_33 PF13671.1 OAJ30771.1 - 0.02 14.7 0.0 0.09 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 OAJ30771.1 - 0.028 14.0 0.1 0.079 12.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 OAJ30771.1 - 0.074 12.7 0.5 0.2 11.3 0.1 1.9 2 0 0 2 2 1 0 NTPase AAA_28 PF13521.1 OAJ30771.1 - 0.076 12.9 0.1 0.55 10.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 OAJ30771.1 - 0.078 12.6 0.0 0.49 10.0 0.0 2.2 1 1 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 OAJ30771.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 OAJ30771.1 - 0.21 11.1 1.9 0.42 10.1 0.0 2.1 1 1 1 2 2 2 0 AAA domain Sec7 PF01369.15 OAJ30773.1 - 1.8e-64 216.9 0.0 4e-64 215.7 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 OAJ30773.1 - 3.6e-52 176.1 6.8 3.6e-52 176.1 4.7 2.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 OAJ30773.1 - 6.6e-25 86.4 0.3 3.1e-23 81.1 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) DUF3730 PF12530.3 OAJ30773.1 - 0.0023 17.8 0.2 0.0023 17.8 0.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3730) BAF1_ABF1 PF04684.8 OAJ30773.1 - 0.99 8.1 7.6 1.6 7.4 5.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GDI PF00996.13 OAJ30774.1 - 3.4e-48 164.0 0.0 5.4e-47 160.0 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor Methyltransf_8 PF05148.10 OAJ30775.1 - 5.4e-52 176.5 0.0 6.8e-26 91.2 0.0 3.1 3 0 0 3 3 3 2 Hypothetical methyltransferase SLD3 PF08639.5 OAJ30775.1 - 0.0026 16.4 10.5 0.0042 15.7 7.3 1.3 1 1 0 1 1 1 1 DNA replication regulator SLD3 Methyltransf_11 PF08241.7 OAJ30775.1 - 0.0035 17.7 0.0 0.63 10.5 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ30775.1 - 0.0074 15.8 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 OAJ30775.1 - 0.012 15.0 0.2 1.7 7.9 0.1 2.4 2 0 0 2 2 2 0 Methyltransferase small domain eIF3_subunit PF08597.5 OAJ30775.1 - 0.33 10.4 10.8 0.17 11.3 4.2 2.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF3140 PF11338.3 OAJ30776.1 - 1.2e-30 105.4 1.4 1.6e-30 105.0 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) Colicin-DNase PF12639.2 OAJ30776.1 - 0.085 13.1 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin DUF3673 PF12425.3 OAJ30776.1 - 0.096 12.5 0.1 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) DUF3907 PF13047.1 OAJ30776.1 - 0.12 12.0 0.1 0.44 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) TMA7 PF09072.5 OAJ30776.1 - 0.66 10.4 3.4 1.3 9.5 2.4 1.5 1 0 0 1 1 1 0 Translation machinery associated TMA7 Rot1 PF10681.4 OAJ30777.1 - 1.9e-51 174.4 1.5 2.4e-51 174.1 1.1 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal VMA21 PF09446.5 OAJ30778.1 - 2e-10 40.4 8.4 2.9e-10 39.9 5.8 1.3 1 0 0 1 1 1 1 VMA21-like domain DnaJ PF00226.26 OAJ30780.1 - 1.1e-15 57.1 0.3 1.9e-15 56.3 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Kinesin PF00225.18 OAJ30781.1 - 4.3e-109 364.2 0.0 6.2e-109 363.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain DUF2370 PF10176.4 OAJ30781.1 - 0.026 13.8 0.8 0.052 12.8 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Atg14 PF10186.4 OAJ30781.1 - 0.033 13.1 1.6 0.058 12.3 1.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Herpes_UL6 PF01763.11 OAJ30781.1 - 0.26 9.4 1.9 0.43 8.7 1.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Seryl_tRNA_N PF02403.17 OAJ30781.1 - 0.95 9.5 6.6 1.1 9.2 2.5 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Y_phosphatase2 PF03162.8 OAJ30782.1 - 8e-46 155.4 0.0 1.2e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Pex2_Pex12 PF04757.9 OAJ30782.1 - 5.5e-38 130.6 4.0 9e-38 129.9 2.8 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Y_phosphatase3 PF13350.1 OAJ30782.1 - 1.4e-05 25.4 0.0 5.6e-05 23.4 0.0 1.9 1 1 1 2 2 2 1 Tyrosine phosphatase family zf-4CXXC_R1 PF10497.4 OAJ30782.1 - 0.035 14.2 2.1 1.4 9.0 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger domain of monoamine-oxidase A repressor R1 RDD PF06271.7 OAJ30782.1 - 0.1 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 RDD family TRP PF06011.7 OAJ30783.1 - 1.3e-52 178.8 16.2 2.5e-36 125.2 9.2 2.3 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 OAJ30783.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 ML-like domain NOA36 PF06524.7 OAJ30783.1 - 2.2 7.4 2.0 3.4 6.8 1.4 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 OAJ30783.1 - 2.9 7.3 3.9 5 6.6 2.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin FLO_LFY PF01698.11 OAJ30783.1 - 5 5.8 4.5 7.5 5.2 3.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein TFIIA PF03153.8 OAJ30784.1 - 0.02 14.8 18.2 0.028 14.3 12.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAPA-1 PF04795.7 OAJ30784.1 - 0.63 10.7 9.4 0.21 12.3 2.1 2.5 2 0 0 2 2 2 0 PAPA-1-like conserved region FAD_binding_3 PF01494.14 OAJ30785.1 - 9.4e-55 186.0 0.9 7.7e-54 183.0 0.6 2.3 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 OAJ30785.1 - 1.3e-18 67.1 0.0 2.5e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.1 OAJ30785.1 - 2.4e-06 27.4 0.0 6.3e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ30785.1 - 6.8e-05 21.9 0.0 0.00013 21.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 OAJ30785.1 - 0.00021 19.8 0.1 0.00034 19.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 OAJ30785.1 - 0.00022 21.1 0.0 0.00046 20.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAJ30785.1 - 0.00026 20.0 0.2 0.00038 19.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAJ30785.1 - 0.0012 19.0 0.0 0.0029 17.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ30785.1 - 0.0012 17.9 0.0 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 OAJ30785.1 - 0.0023 16.6 0.0 0.0036 15.9 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.19 OAJ30785.1 - 0.0034 16.2 0.5 0.0034 16.2 0.4 1.8 3 1 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.22 OAJ30785.1 - 0.0073 16.6 0.1 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ30785.1 - 0.01 15.6 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding ThiF PF00899.16 OAJ30785.1 - 0.038 13.8 0.3 0.087 12.6 0.2 1.6 1 0 0 1 1 1 0 ThiF family K_oxygenase PF13434.1 OAJ30785.1 - 0.051 12.4 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) ApbA PF02558.11 OAJ30785.1 - 0.095 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 OAJ30785.1 - 0.097 12.6 0.1 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 OAJ30785.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AA_permease PF00324.16 OAJ30787.1 - 1.8e-123 412.4 37.7 2.2e-123 412.1 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAJ30787.1 - 1.2e-39 136.0 42.5 1.6e-39 135.7 29.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 OAJ30787.1 - 0.22 11.1 1.2 15 5.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2665) DUF4481 PF14800.1 OAJ30787.1 - 3.7 6.3 4.8 6.5 5.5 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) TPP_enzyme_N PF02776.13 OAJ30788.1 - 1e-34 119.4 0.1 1.5e-34 118.9 0.1 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAJ30788.1 - 1.6e-27 95.9 0.0 3.2e-26 91.7 0.0 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 OAJ30788.1 - 6e-16 58.3 0.2 1.1e-14 54.2 0.0 2.8 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Cutinase PF01083.17 OAJ30789.1 - 4.8e-10 39.4 0.0 7.2e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Cutinase Pkinase PF00069.20 OAJ30790.1 - 1.8e-60 204.3 0.0 1.5e-41 142.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ30790.1 - 9.7e-26 90.3 0.0 1.1e-19 70.5 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ30790.1 - 0.00085 18.3 0.0 0.00085 18.3 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Pox_ser-thr_kin PF05445.6 OAJ30790.1 - 0.067 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 OAJ30790.1 - 0.087 12.5 0.0 0.087 12.5 0.0 4.1 2 1 2 4 4 4 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ30790.1 - 0.17 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Med15 PF09606.5 OAJ30790.1 - 0.45 8.6 99.1 0.75 7.9 68.7 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-C2H2_4 PF13894.1 OAJ30791.1 - 6.1e-08 32.4 7.9 0.0016 18.6 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 OAJ30791.1 - 0.00019 21.5 12.5 0.0019 18.4 0.5 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAJ30791.1 - 0.069 13.4 0.8 6.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-met PF12874.2 OAJ30791.1 - 0.11 12.7 2.4 0.28 11.4 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ETC_C1_NDUFA5 PF04716.9 OAJ30792.1 - 3e-16 58.6 0.3 4.5e-16 58.1 0.2 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Prefoldin_2 PF01920.15 OAJ30792.1 - 0.0007 19.3 0.6 0.001 18.7 0.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit Abhydrolase_6 PF12697.2 OAJ30793.1 - 9.1e-29 100.9 3.6 4.8e-28 98.5 2.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ30793.1 - 3.2e-10 39.9 0.1 1.3e-06 28.1 0.1 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ30793.1 - 3.6e-10 39.7 0.0 1.1e-09 38.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ30793.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Glyoxalase_2 PF12681.2 OAJ30794.1 - 4.1e-11 43.4 0.0 4.2e-10 40.1 0.0 2.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 OAJ30794.1 - 7.4e-05 22.7 0.0 0.00033 20.6 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BMF PF15185.1 OAJ30794.1 - 0.088 12.0 2.0 0.16 11.2 1.4 1.3 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis DUF3235 PF11574.3 OAJ30794.1 - 0.42 10.8 5.4 1.4 9.1 3.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) SIMPL PF04402.9 OAJ30794.1 - 8.1 6.2 12.9 12 5.6 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Ribophorin_II PF05817.9 OAJ30795.1 - 0.00017 20.0 1.8 0.00027 19.2 1.3 1.3 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II RIC1 PF07064.8 OAJ30798.1 - 1.3e-69 234.5 1.6 1.5e-40 139.2 0.1 3.1 3 0 0 3 3 3 3 RIC1 Formyl_trans_N PF00551.14 OAJ30799.1 - 0.001 18.6 0.3 0.0012 18.3 0.2 1.1 1 0 0 1 1 1 1 Formyl transferase DUF4551 PF15087.1 OAJ30799.1 - 0.43 8.9 4.2 0.49 8.6 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Amidohydro_2 PF04909.9 OAJ30800.1 - 0.0038 16.8 0.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase TBCA PF02970.11 OAJ30801.1 - 2.7e-27 94.6 5.9 2.8e-27 94.6 4.1 2.0 1 1 1 2 2 2 1 Tubulin binding cofactor A TaqI_C PF12950.2 OAJ30801.1 - 0.021 14.5 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain RdRP_4 PF02123.11 OAJ30801.1 - 0.14 10.8 1.4 0.14 10.8 1.0 1.1 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase HN PF00423.14 OAJ30801.1 - 0.15 10.3 1.6 0.16 10.1 1.1 1.0 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase Fib_alpha PF08702.5 OAJ30801.1 - 2.3 8.3 8.0 1.2 9.2 0.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family RHD3 PF05879.7 OAJ30802.1 - 4.3e-247 821.7 0.0 5.4e-247 821.4 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Miro PF08477.8 OAJ30802.1 - 1.7e-06 28.5 0.6 8.3e-06 26.3 0.1 2.2 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 OAJ30802.1 - 1e-05 25.4 0.3 0.00013 21.8 0.0 2.3 2 0 0 2 2 2 1 Dynamin family GBP PF02263.14 OAJ30802.1 - 1.3e-05 24.4 0.2 2.6e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 OAJ30802.1 - 7.2e-05 22.7 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 OAJ30802.1 - 0.0034 17.3 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ30802.1 - 0.013 15.5 0.3 1.4 8.8 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain KAT11 PF08214.6 OAJ30803.1 - 8.1e-25 87.6 0.1 5.1e-13 48.8 0.0 4.2 3 2 0 3 3 3 2 Histone acetylation protein zf-PARP PF00645.13 OAJ30803.1 - 2.8e-18 65.9 0.0 5.7e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Rad52_Rad22 PF04098.10 OAJ30804.1 - 2.6e-57 192.8 0.0 4.2e-57 192.2 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein PAT1 PF09770.4 OAJ30804.1 - 0.44 8.7 6.5 0.72 8.0 4.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF21 PF01595.15 OAJ30805.1 - 2.1e-33 115.1 2.8 2.1e-33 115.1 2.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF21 CBS PF00571.23 OAJ30805.1 - 1e-05 25.2 1.1 1.1 9.1 0.1 3.5 3 0 0 3 3 3 3 CBS domain Sec2p PF06428.6 OAJ30806.1 - 1.4e-14 53.7 7.4 4.3e-14 52.1 5.1 1.8 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p DUF572 PF04502.8 OAJ30806.1 - 2.6 7.1 27.1 0.013 14.7 4.4 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) Lyase_aromatic PF00221.14 OAJ30807.1 - 1.1e-126 423.1 2.5 1.4e-126 422.7 1.7 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase MFS_1 PF07690.11 OAJ30808.1 - 2.1e-33 115.4 33.5 1.7e-31 109.2 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ30808.1 - 2.1e-12 46.3 20.2 3.2e-12 45.7 14.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 OAJ30808.1 - 2.2e-06 26.1 4.8 4.8e-06 25.0 2.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Transp_cyt_pur PF02133.10 OAJ30809.1 - 3.5e-19 68.6 30.7 4.7e-19 68.2 21.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin OrfB_Zn_ribbon PF07282.6 OAJ30810.1 - 7.4e-14 51.1 0.3 1.3e-13 50.4 0.2 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.14 OAJ30810.1 - 5.2e-07 29.3 0.0 7.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Probable transposase DZR PF12773.2 OAJ30810.1 - 0.11 12.3 0.2 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon Apolipoprotein PF01442.13 OAJ30810.1 - 0.11 11.9 0.3 0.2 11.1 0.2 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain zf-TFIIB PF13453.1 OAJ30810.1 - 0.24 10.6 2.0 0.96 8.6 1.4 2.0 1 1 0 1 1 1 0 Transcription factor zinc-finger ADH_N PF08240.7 OAJ30811.1 - 2.3e-25 88.4 0.6 4.4e-25 87.5 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ30811.1 - 2.3e-21 75.6 0.1 3.6e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ30811.1 - 0.015 16.1 0.0 0.036 14.9 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 OAJ30811.1 - 0.019 14.6 0.1 0.031 13.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 OAJ30811.1 - 0.023 13.1 0.2 0.032 12.7 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 OAJ30811.1 - 0.039 13.3 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 OAJ30811.1 - 0.04 14.4 0.0 0.092 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sad1_UNC PF07738.8 OAJ30812.1 - 6.5e-22 77.7 0.0 4.1e-10 39.5 0.0 3.8 2 2 0 2 2 2 2 Sad1 / UNC-like C-terminal Mgr1 PF08602.5 OAJ30812.1 - 0.13 11.2 2.7 0.21 10.5 1.8 1.4 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit AAA_13 PF13166.1 OAJ30812.1 - 0.32 9.4 12.0 0.6 8.4 8.3 1.4 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 OAJ30812.1 - 0.49 9.5 11.9 0.35 10.0 2.1 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 OAJ30812.1 - 2.3 8.3 6.6 1.4 9.0 2.0 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 OAJ30812.1 - 4.1 7.2 10.6 4.9 6.9 0.3 3.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 OAJ30812.1 - 9.4 5.5 23.6 2.2 7.6 3.1 2.8 2 1 1 3 3 3 0 Intermediate filament protein Aminotran_5 PF00266.14 OAJ30813.1 - 1.7e-07 30.3 0.0 2.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SprA-related PF12118.3 OAJ30814.1 - 0.015 14.6 39.2 0.0078 15.5 8.3 2.4 2 0 0 2 2 2 0 SprA-related family Neur_chan_memb PF02932.11 OAJ30814.1 - 2.2 8.0 9.2 11 5.7 0.3 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF3043 PF11241.3 OAJ30814.1 - 6.4 6.3 8.6 0.47 10.0 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) CopD PF05425.8 OAJ30815.1 - 0.16 12.2 6.8 0.46 10.7 0.3 2.7 2 1 1 3 3 3 0 Copper resistance protein D FAD_binding_2 PF00890.19 OAJ30817.1 - 1.4e-47 162.4 0.7 2e-47 162.0 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAJ30817.1 - 0.00026 20.0 0.1 0.00035 19.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAJ30817.1 - 0.0018 17.3 0.1 0.0032 16.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 OAJ30817.1 - 0.0025 16.9 0.2 0.0035 16.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAJ30817.1 - 0.0053 16.6 0.1 0.0078 16.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAJ30817.1 - 0.0079 15.1 2.0 0.011 14.5 1.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 OAJ30817.1 - 0.065 11.6 0.5 0.11 10.9 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 OAJ30818.1 - 9.9e-55 186.0 0.0 1.4e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 OAJ30818.1 - 1.6e-47 160.5 2.9 2.2e-47 160.0 2.0 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term AAA PF00004.24 OAJ30819.1 - 6.1e-14 52.3 0.0 9.6e-13 48.4 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ30819.1 - 4.2e-08 33.4 4.8 4.3e-08 33.3 0.0 3.3 3 2 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 OAJ30819.1 - 7.3e-07 29.3 0.0 4.7e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ30819.1 - 3.8e-05 23.3 3.4 0.00037 20.2 0.0 3.1 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 OAJ30819.1 - 0.019 14.6 0.2 6.9 6.2 0.0 3.3 2 1 0 2 2 2 0 Archaeal ATPase Viral_NABP PF05515.6 OAJ30819.1 - 0.034 14.4 0.4 0.087 13.0 0.3 1.6 1 0 0 1 1 1 0 Viral nucleic acid binding AAA_11 PF13086.1 OAJ30819.1 - 0.055 13.0 1.7 0.094 12.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 OAJ30819.1 - 0.056 13.0 0.0 0.41 10.3 0.0 2.2 1 1 0 1 1 1 0 NACHT domain Nop14 PF04147.7 OAJ30819.1 - 2.4 5.9 18.7 3.6 5.3 13.0 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 OAJ30819.1 - 3.9 6.4 21.9 8.8 5.2 15.2 1.5 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 OAJ30819.1 - 5.3 4.9 12.5 10 4.0 8.7 1.4 1 0 0 1 1 1 0 CDC45-like protein SPT2 PF08243.6 OAJ30820.1 - 1.6e-17 63.8 1.2 1.6e-17 63.8 0.8 5.3 5 0 0 5 5 5 1 SPT2 chromatin protein F-box-like PF12937.2 OAJ30821.1 - 0.00037 20.1 0.1 0.0017 18.0 0.0 2.2 2 0 0 2 2 2 1 F-box-like DUF2433 PF10360.4 OAJ30823.1 - 5.2e-41 140.0 0.1 1.1e-40 139.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) DUF605 PF04652.11 OAJ30823.1 - 0.81 9.0 29.8 0.16 11.3 10.7 2.3 2 0 0 2 2 2 0 Vta1 like PAT1 PF09770.4 OAJ30823.1 - 0.86 7.7 3.9 1.4 7.1 2.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GTP_EFTU PF00009.22 OAJ30824.1 - 1.2e-30 106.3 0.0 6e-30 104.0 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 OAJ30824.1 - 2e-15 56.6 0.1 6.3e-15 54.9 0.0 1.9 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 OAJ30824.1 - 1.4e-10 41.1 10.5 1.1e-09 38.2 0.2 3.8 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAJ30824.1 - 1.1e-06 28.5 0.0 3.6e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 OAJ30824.1 - 0.0091 16.1 0.1 0.036 14.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain PapB PF03333.8 OAJ30824.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein AAA_16 PF13191.1 OAJ30824.1 - 0.38 10.7 0.0 0.38 10.7 0.0 3.1 2 0 0 2 2 2 0 AAA ATPase domain Trm112p PF03966.11 OAJ30825.1 - 6.9e-17 61.5 0.1 1e-16 61.0 0.1 1.3 1 0 0 1 1 1 1 Trm112p-like protein zinc_ribbon_5 PF13719.1 OAJ30825.1 - 0.11 12.1 0.1 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain HypA PF01155.14 OAJ30825.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.7 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Myosin_tail_1 PF01576.14 OAJ30826.1 - 0.0035 15.1 12.6 0.083 10.5 1.2 2.0 1 1 1 2 2 2 2 Myosin tail Leu_zip PF15294.1 OAJ30826.1 - 0.011 14.8 3.8 0.011 14.8 2.6 1.4 1 1 0 1 1 1 0 Leucine zipper ATG_C PF09333.6 OAJ30826.1 - 0.032 14.3 3.1 0.74 10.0 1.3 3.3 1 1 1 2 2 2 0 ATG C terminal domain Laminin_II PF06009.7 OAJ30826.1 - 0.052 13.2 10.1 1.1 8.9 0.1 2.6 1 1 1 2 2 2 0 Laminin Domain II Glyco_tran_28_C PF04101.11 OAJ30826.1 - 0.12 11.9 1.0 0.25 10.9 0.7 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain APG6 PF04111.7 OAJ30826.1 - 0.86 8.5 6.4 1.2 8.1 4.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2968 PF11180.3 OAJ30826.1 - 0.87 8.9 10.9 0.24 10.7 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) AAA_13 PF13166.1 OAJ30826.1 - 1.8 6.9 8.1 2.4 6.5 5.6 1.1 1 0 0 1 1 1 0 AAA domain Sec2p PF06428.6 OAJ30826.1 - 1.9 8.3 12.2 0.5 10.2 4.2 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p EHN PF06441.7 OAJ30827.1 - 2e-26 92.0 0.0 3.7e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 OAJ30827.1 - 2.3e-07 30.9 3.7 5.9e-07 29.5 1.2 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ30827.1 - 0.0041 16.7 0.1 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Polysacc_deac_1 PF01522.16 OAJ30828.1 - 2e-22 79.1 0.0 7.5e-22 77.2 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase DNA_ligase_A_N PF04675.9 OAJ30829.1 - 6e-23 81.5 0.0 8.4e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 DNA ligase N terminus DUF4536 PF15055.1 OAJ30829.1 - 0.045 13.8 0.0 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Abhydrolase_3 PF07859.8 OAJ30831.1 - 1.1e-29 103.5 0.0 2.2e-29 102.5 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAJ30831.1 - 0.00013 20.7 0.0 0.00022 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 OAJ30831.1 - 0.00021 21.0 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ30831.1 - 0.17 11.1 0.0 4.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family GYF PF02213.11 OAJ30832.1 - 3.7e-18 64.8 0.7 8e-18 63.7 0.5 1.5 1 0 0 1 1 1 1 GYF domain zf-DHHC PF01529.15 OAJ30833.1 - 1.3e-20 73.5 1.8 6.1e-19 68.0 0.0 2.2 1 1 0 2 2 2 1 DHHC palmitoyltransferase DUF1180 PF06679.7 OAJ30833.1 - 0.015 15.1 0.1 0.032 14.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4583 PF15190.1 OAJ30833.1 - 0.34 10.5 4.0 0.25 10.9 0.8 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4583) GCR1_C PF12550.3 OAJ30836.1 - 1.1e-19 70.1 0.5 2.1e-19 69.1 0.3 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Glyco_hydro_17 PF00332.13 OAJ30836.1 - 0.0085 15.1 0.1 0.016 14.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DUF2416 PF10315.4 OAJ30837.1 - 1.9e-09 37.6 2.4 8.8e-09 35.5 1.7 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) Mid1 PF12929.2 OAJ30838.1 - 1.8e-59 201.5 0.0 2.7e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component MRP-S25 PF13741.1 OAJ30839.1 - 1.6e-45 155.3 0.0 1.2e-44 152.5 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 OAJ30839.1 - 9.7e-05 22.2 2.1 0.017 15.0 0.0 2.4 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S23 SR-25 PF10500.4 OAJ30839.1 - 4.3 6.7 11.2 7.6 5.9 7.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GN3L_Grn1 PF08701.6 OAJ30840.1 - 9.3e-24 83.1 18.5 9.3e-24 83.1 12.9 2.4 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase zf-H2C2_2 PF13465.1 OAJ30841.1 - 1.6e-05 24.9 10.1 0.00035 20.7 1.1 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ30841.1 - 0.00038 20.6 8.9 0.066 13.5 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type GTP_EFTU PF00009.22 OAJ30842.1 - 2.2e-47 160.9 0.0 4e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 OAJ30842.1 - 9.6e-22 76.6 0.3 4.3e-10 39.3 0.0 2.7 2 0 0 2 2 2 2 Elongation Factor G, domain II EFG_C PF00679.19 OAJ30842.1 - 7.4e-17 61.0 0.4 2.7e-14 52.8 0.3 2.5 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 OAJ30842.1 - 2e-07 31.0 0.0 7.9e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 OAJ30842.1 - 0.068 12.7 0.0 0.32 10.5 0.0 2.0 2 0 0 2 2 2 0 Elongation factor G, domain IV PPR_1 PF12854.2 OAJ30844.1 - 0.005 16.2 0.0 0.0089 15.4 0.0 1.4 1 0 0 1 1 1 1 PPR repeat PPR PF01535.15 OAJ30844.1 - 0.012 15.5 0.0 0.076 13.0 0.0 2.1 2 0 0 2 2 2 0 PPR repeat PPR_2 PF13041.1 OAJ30844.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 PPR repeat family dCMP_cyt_deam_1 PF00383.17 OAJ30845.1 - 0.072 12.7 0.0 0.2 11.2 0.0 1.8 1 1 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region F_actin_cap_B PF01115.12 OAJ30846.1 - 6.7e-86 287.4 0.0 8e-86 287.1 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit AdoHcyase PF05221.12 OAJ30847.1 - 4.4e-139 461.9 0.0 5e-139 461.7 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 OAJ30847.1 - 1.7e-83 278.3 2.1 2.5e-83 277.7 1.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 OAJ30847.1 - 6.3e-09 35.2 0.1 1.4e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 OAJ30847.1 - 0.00057 19.2 0.1 0.00095 18.5 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 OAJ30847.1 - 0.0029 17.5 0.1 0.0067 16.4 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain DUF4448 PF14610.1 OAJ30847.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) NAD_binding_7 PF13241.1 OAJ30847.1 - 0.077 13.2 0.2 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding WD40 PF00400.27 OAJ30848.1 - 1.5e-16 59.5 6.9 3e-05 23.7 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.1 OAJ30848.1 - 1.6e-06 28.1 0.8 0.00051 20.2 0.0 4.0 3 0 0 3 3 3 1 PQQ-like domain polyprenyl_synt PF00348.12 OAJ30849.1 - 6.7e-40 136.5 0.0 4.3e-19 68.3 0.0 4.1 4 0 0 4 4 4 4 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 OAJ30849.1 - 0.026 14.0 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Clat_adaptor_s PF01217.15 OAJ30850.1 - 1.1e-54 184.0 0.2 1.3e-54 183.8 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PAXNEB PF05625.6 OAJ30852.1 - 1.7e-28 99.5 0.0 1e-17 64.0 0.0 3.9 4 0 0 4 4 4 3 PAXNEB protein DUF2457 PF10446.4 OAJ30852.1 - 0.26 9.9 1.0 0.53 8.9 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SRI PF08236.6 OAJ30853.1 - 0.12 12.3 2.5 0.12 12.2 1.7 1.1 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain 2OG-FeII_Oxy_2 PF13532.1 OAJ30855.1 - 1e-26 93.9 0.0 1.5e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ30855.1 - 0.0023 18.2 0.0 0.012 15.8 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily HSP90 PF00183.13 OAJ30856.1 - 8.3e-59 199.3 1.5 1e-36 126.4 0.7 2.2 1 1 1 2 2 2 2 Hsp90 protein Scm3 PF10384.4 OAJ30856.1 - 1.3e-07 30.9 0.5 1.1e-06 28.0 0.4 2.2 2 0 0 2 2 2 1 Centromere protein Scm3 TRAM_LAG1_CLN8 PF03798.11 OAJ30857.1 - 4.4e-39 134.1 18.1 5.4e-39 133.7 12.5 1.1 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 OAJ30857.1 - 0.00027 20.3 2.0 0.00031 20.1 0.0 2.0 2 0 0 2 2 2 1 TRAM1-like protein DUF4011 PF13195.1 OAJ30857.1 - 0.082 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Oxysterol_BP PF01237.13 OAJ30858.1 - 3.7e-56 190.1 6.8 1.1e-45 155.6 0.2 3.0 3 0 0 3 3 3 3 Oxysterol-binding protein Asp_protease_2 PF13650.1 OAJ30859.1 - 0.041 14.3 0.0 0.34 11.4 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.1 OAJ30859.1 - 0.045 13.5 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Amidohydro_1 PF01979.15 OAJ30860.1 - 2.1e-42 145.9 0.0 3.6e-29 102.4 0.0 2.1 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 OAJ30860.1 - 9.3e-08 31.6 0.0 2.1e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 OAJ30860.1 - 2.4e-05 24.0 0.1 9.2e-05 22.1 0.1 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 OAJ30860.1 - 2.6e-05 24.3 0.4 0.35 10.8 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase A_deaminase PF00962.17 OAJ30860.1 - 0.00042 19.3 0.0 0.0007 18.6 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Pkinase PF00069.20 OAJ30861.1 - 2.5e-66 223.5 0.0 5.2e-66 222.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ30861.1 - 3.5e-52 177.0 0.0 5.3e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ30861.1 - 9.7e-07 28.0 0.0 8e-05 21.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like C1_1 PF00130.17 OAJ30861.1 - 0.00062 19.4 7.6 0.0011 18.6 5.2 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CH PF00307.26 OAJ30861.1 - 0.0044 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 OAJ30861.1 - 0.062 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 CDC24 Calponin PHD PF00628.24 OAJ30861.1 - 0.39 10.4 7.0 0.71 9.6 4.9 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 OAJ30861.1 - 1.2 8.8 7.2 2.3 8.0 5.0 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 TPR_12 PF13424.1 OAJ30862.1 - 3.1e-05 23.8 10.9 0.097 12.6 0.3 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ30862.1 - 0.00072 19.1 1.4 12 6.0 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ30862.1 - 0.02 14.5 7.6 7.2 6.3 0.1 4.5 4 1 0 4 4 4 0 TPR repeat TPR_1 PF00515.23 OAJ30862.1 - 0.11 12.1 8.2 14 5.4 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ30862.1 - 0.13 12.2 15.0 1.1 9.3 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ30862.1 - 0.29 11.0 4.2 27 4.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ30862.1 - 5.4 7.8 16.6 19 6.0 1.7 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 OAJ30863.1 - 2.5e-10 40.0 10.1 3.3e-05 23.9 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ30863.1 - 4.8e-07 29.6 10.0 0.0044 17.2 2.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ30863.1 - 3.7e-06 26.9 2.0 3.7e-06 26.9 1.4 3.1 4 0 0 4 4 4 1 Zinc-finger double domain AKAP2_C PF15304.1 OAJ30863.1 - 6.6 6.2 10.8 0.27 10.8 2.2 2.2 2 0 0 2 2 2 0 A-kinase anchor protein 2 C-terminus NTP_transf_2 PF01909.18 OAJ30864.1 - 0.00023 21.4 0.0 0.00041 20.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF3395 PF11875.3 OAJ30865.1 - 1.1e-33 116.0 0.0 2.6e-33 114.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 OAJ30865.1 - 9.6e-22 76.4 0.6 2.5e-21 75.1 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain DDE_3 PF13358.1 OAJ30866.1 - 1.1e-28 99.7 0.0 2.8e-28 98.4 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAJ30866.1 - 1.6e-08 35.2 0.1 1.2e-07 32.3 0.0 2.4 1 1 0 1 1 1 1 Homeodomain-like domain rve PF00665.21 OAJ30866.1 - 4.2e-05 23.6 0.0 0.00011 22.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_29 PF13551.1 OAJ30866.1 - 6.9e-05 22.9 0.0 0.00024 21.1 0.0 2.0 1 1 0 1 1 1 1 Winged helix-turn helix HTH_33 PF13592.1 OAJ30866.1 - 0.00069 19.1 0.1 0.0019 17.6 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_21 PF13276.1 OAJ30866.1 - 0.015 15.2 0.3 0.22 11.5 0.0 2.7 3 0 0 3 3 3 0 HTH-like domain HTH_7 PF02796.10 OAJ30866.1 - 0.02 14.7 0.0 0.15 11.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase FlgN PF05130.7 OAJ30867.1 - 0.58 10.4 2.3 17 5.6 0.1 2.1 1 1 1 2 2 2 0 FlgN protein RNB PF00773.14 OAJ30868.1 - 1.9e-93 313.3 0.0 3.6e-93 312.4 0.0 1.5 1 0 0 1 1 1 1 RNB domain DUF1751 PF08551.5 OAJ30870.1 - 2.8e-26 91.7 7.1 5.4e-26 90.8 4.9 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 OAJ30870.1 - 0.0013 18.7 12.6 0.003 17.5 8.8 1.6 1 0 0 1 1 1 1 Rhomboid family ETF PF01012.16 OAJ30871.1 - 1.7e-35 122.1 3.8 2.3e-35 121.7 2.6 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Rad51 PF08423.6 OAJ30872.1 - 0.041 12.7 0.0 4.8 5.9 0.0 2.1 2 0 0 2 2 2 0 Rad51 HRDC PF00570.18 OAJ30872.1 - 0.061 13.0 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 HRDC domain TraF PF13728.1 OAJ30872.1 - 0.067 12.6 0.1 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein HTH_10 PF04967.7 OAJ30873.1 - 0.0064 16.0 0.0 0.025 14.1 0.0 1.9 2 0 0 2 2 2 1 HTH DNA binding domain IGR PF09597.5 OAJ30874.1 - 5.7e-09 35.7 0.2 4e-08 33.0 0.1 2.2 2 0 0 2 2 2 1 IGR protein motif SLT PF01464.15 OAJ30875.1 - 0.00044 19.7 1.0 0.0048 16.3 0.0 2.6 2 1 0 2 2 2 1 Transglycosylase SLT domain DEAD PF00270.24 OAJ30876.1 - 5.7e-39 133.3 0.0 1.2e-38 132.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ30876.1 - 2.6e-21 75.2 0.0 6.3e-21 74.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 OAJ30876.1 - 6.2e-18 64.3 2.3 6.2e-18 64.3 1.6 2.8 3 0 0 3 3 3 1 DBP10CT (NUC160) domain ResIII PF04851.10 OAJ30876.1 - 0.0035 17.1 0.0 0.089 12.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit GHMP_kinases_C PF08544.8 OAJ30877.1 - 5.5e-11 42.5 0.0 1.2e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 OAJ30877.1 - 6.3e-05 22.9 0.7 0.00018 21.4 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF4142 PF13628.1 OAJ30877.1 - 0.034 14.1 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) Ribosomal_L7Ae PF01248.21 OAJ30878.1 - 3.7e-23 80.8 0.0 4.3e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L37e PF01907.14 OAJ30879.1 - 2.1e-24 85.0 13.7 3.5e-24 84.3 9.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 OAJ30879.1 - 0.0018 18.0 1.8 0.0028 17.4 1.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon LIM PF00412.17 OAJ30879.1 - 0.046 13.7 2.3 0.07 13.2 1.6 1.3 1 0 0 1 1 1 0 LIM domain SelR PF01641.13 OAJ30879.1 - 0.049 13.3 0.1 0.049 13.3 0.1 1.2 1 0 0 1 1 1 0 SelR domain Radical_SAM PF04055.16 OAJ30879.1 - 0.052 13.7 0.5 0.059 13.5 0.3 1.1 1 0 0 1 1 1 0 Radical SAM superfamily HypA PF01155.14 OAJ30879.1 - 0.095 12.3 1.0 0.14 11.8 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 OAJ30879.1 - 1.2 8.4 3.5 3.3 7.0 2.4 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zf-C2H2_3 PF13878.1 OAJ30879.1 - 1.4 8.5 5.2 5.4 6.6 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-C3HC4 PF00097.20 OAJ30879.1 - 4.7 6.9 7.6 7.6 6.2 5.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S14 PF00253.16 OAJ30879.1 - 8.8 5.7 11.6 0.53 9.7 0.5 2.7 1 1 2 3 3 3 0 Ribosomal protein S14p/S29e EnY2 PF10163.4 OAJ30880.1 - 4.1e-11 42.6 0.0 6.9e-11 41.9 0.0 1.4 2 0 0 2 2 2 1 Transcription factor e(y)2 Ten1 PF12658.2 OAJ30880.1 - 0.014 15.1 0.0 0.018 14.7 0.0 1.3 1 1 0 1 1 1 0 Telomere capping, CST complex subunit Mit_KHE1 PF10173.4 OAJ30880.1 - 0.035 13.9 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Prp18 PF02840.10 OAJ30880.1 - 0.055 13.2 0.7 0.19 11.5 0.5 1.7 1 1 1 2 2 2 0 Prp18 domain NRDE-2 PF08424.5 OAJ30880.1 - 0.056 12.3 2.7 0.061 12.1 1.9 1.1 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference DUF2309 PF10070.4 OAJ30880.1 - 0.12 10.4 0.5 0.14 10.2 0.3 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) PRP1_N PF06424.7 OAJ30880.1 - 0.14 12.4 1.2 0.21 11.9 0.9 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal CK_II_beta PF01214.13 OAJ30880.1 - 0.15 11.5 0.4 0.2 11.1 0.3 1.2 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Med15 PF09606.5 OAJ30880.1 - 0.81 7.8 8.3 0.81 7.8 5.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TSA PF03249.8 OAJ30880.1 - 1.7 7.0 9.5 2 6.8 6.6 1.0 1 0 0 1 1 1 0 Type specific antigen DUF4239 PF14023.1 OAJ30881.1 - 0.56 9.5 27.3 0.68 9.2 1.7 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4239) Alg6_Alg8 PF03155.10 OAJ30883.1 - 2.9e-108 362.7 13.9 2.5e-48 165.0 0.0 3.0 3 0 0 3 3 3 3 ALG6, ALG8 glycosyltransferase family ALG3 PF05208.8 OAJ30883.1 - 0.82 8.8 5.6 4.2 6.5 0.7 2.5 1 1 1 2 2 2 0 ALG3 protein Glucan_synthase PF02364.10 OAJ30884.1 - 0 1365.9 0.0 0 1365.5 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 OAJ30884.1 - 2e-37 127.6 0.0 4.6e-37 126.4 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DASH_Duo1 PF08651.5 OAJ30885.1 - 9.6e-18 63.5 0.0 1.4e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 Med2 PF11214.3 OAJ30885.1 - 4.1 7.4 6.6 15 5.7 4.5 1.9 1 1 0 1 1 1 0 Mediator complex subunit 2 AAA_22 PF13401.1 OAJ30886.1 - 5.8e-13 49.1 0.0 1.1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 OAJ30886.1 - 1.9e-09 37.7 0.0 7.5e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ30886.1 - 8.2e-07 29.1 4.5 1.4e-06 28.4 0.6 2.9 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 OAJ30886.1 - 0.00013 21.6 0.0 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 OAJ30886.1 - 0.0052 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 OAJ30886.1 - 0.026 14.2 0.0 0.075 12.7 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase PIF1 PF05970.9 OAJ30886.1 - 0.049 12.5 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Glucosamine_iso PF01182.15 OAJ30887.1 - 9.8e-67 224.5 0.0 1.1e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar_tr PF00083.19 OAJ30889.1 - 0.0087 14.6 2.7 0.065 11.8 0.0 3.3 3 1 1 4 4 4 1 Sugar (and other) transporter TRAP_alpha PF03896.11 OAJ30889.1 - 0.023 13.7 0.3 0.12 11.3 0.0 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.8 OAJ30889.1 - 0.95 9.0 7.4 0.3 10.6 1.3 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 OAJ30889.1 - 3 7.3 9.3 1.4 8.4 3.6 2.1 2 0 0 2 2 2 0 Nucleoplasmin VID27 PF08553.5 OAJ30889.1 - 8.7 4.4 5.0 13 3.8 3.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein tRNA-synt_2b PF00587.20 OAJ30890.1 - 2.4e-43 147.6 0.0 4.1e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ30890.1 - 5.1e-12 45.5 0.1 1.3e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 Anticodon binding domain UbiA PF01040.13 OAJ30891.1 - 1.2e-22 80.4 27.7 2.5e-22 79.3 19.2 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family NIF PF03031.13 OAJ30892.1 - 5.9e-38 130.0 0.0 8.3e-38 129.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HORMA PF02301.13 OAJ30893.1 - 8.8e-39 133.1 0.0 1e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 HORMA domain FlaG PF03646.10 OAJ30893.1 - 0.074 13.2 0.0 7.8 6.6 0.0 2.3 2 0 0 2 2 2 0 FlaG protein Flag1_repress PF03614.8 OAJ30894.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Repressor of phase-1 flagellin DUF3632 PF12311.3 OAJ30895.1 - 0.061 13.1 0.8 11 5.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3632) Det1 PF09737.4 OAJ30895.1 - 0.5 9.0 0.6 0.8 8.3 0.4 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 Nop14 PF04147.7 OAJ30896.1 - 3.3 5.4 18.8 4.9 4.9 13.0 1.3 1 0 0 1 1 1 0 Nop14-like family DUF1793 PF08760.6 OAJ30897.1 - 1.2e-66 223.8 1.1 2e-66 223.0 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF1014 PF06244.7 OAJ30898.1 - 2.2e-20 73.0 26.9 1.2e-18 67.4 18.6 3.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) DUF4551 PF15087.1 OAJ30898.1 - 3.4 5.9 10.1 4.2 5.6 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Cript PF10235.4 OAJ30899.1 - 4.9e-24 84.5 1.1 4.9e-24 84.5 0.8 1.7 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT zinc_ribbon_2 PF13240.1 OAJ30899.1 - 0.036 13.5 1.7 0.036 13.5 1.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain C6_DPF PF10170.4 OAJ30899.1 - 0.095 12.7 5.1 0.3 11.1 2.0 2.2 2 1 0 2 2 2 0 Cysteine-rich domain Herpes_capsid PF06112.6 OAJ30899.1 - 0.2 11.6 3.7 0.23 11.5 2.6 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF2039 PF10217.4 OAJ30899.1 - 0.44 10.5 12.6 0.12 12.3 4.8 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-ribbon_3 PF13248.1 OAJ30899.1 - 1.1 8.5 12.0 0.34 10.1 0.7 3.2 3 0 0 3 3 3 0 zinc-ribbon domain HSP70 PF00012.15 OAJ30900.1 - 9.1e-67 225.3 1.9 1.5e-39 135.4 0.0 2.4 3 0 0 3 3 3 2 Hsp70 protein Actin PF00022.14 OAJ30900.1 - 0.00058 18.3 0.2 0.12 10.8 0.0 2.1 1 1 1 2 2 2 2 Actin PilM_2 PF11104.3 OAJ30900.1 - 0.03 13.2 0.0 0.19 10.5 0.0 2.0 1 1 0 1 1 1 0 Type IV pilus assembly protein PilM; An_peroxidase PF03098.10 OAJ30901.1 - 7.3e-69 232.5 0.0 8.9e-67 225.6 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 OAJ30901.1 - 3.1e-15 55.6 0.0 3.7e-14 52.1 0.0 2.2 2 0 0 2 2 2 1 Cytochrome P450 RINGv PF12906.2 OAJ30902.1 - 2.2e-15 56.4 11.6 3.9e-15 55.6 8.0 1.4 1 0 0 1 1 1 1 RING-variant domain HemY_N PF07219.8 OAJ30902.1 - 0.029 13.9 3.1 0.6 9.6 0.2 3.0 2 0 0 2 2 2 0 HemY protein N-terminus DUF2256 PF10013.4 OAJ30902.1 - 0.038 13.7 0.2 0.038 13.7 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_2 PF13639.1 OAJ30902.1 - 0.23 11.3 10.1 0.55 10.1 7.0 1.7 1 0 0 1 1 1 0 Ring finger domain DUF2968 PF11180.3 OAJ30902.1 - 0.41 10.0 4.6 0.54 9.6 2.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) FANCL_C PF11793.3 OAJ30902.1 - 3.4 7.6 8.5 8.4 6.4 5.9 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Actin PF00022.14 OAJ30903.1 - 6e-117 390.3 0.0 7.4e-117 390.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 OAJ30903.1 - 0.024 13.2 0.0 0.2 10.2 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein PilX_N PF14341.1 OAJ30904.1 - 0.051 13.2 1.8 0.14 11.8 1.3 1.7 1 0 0 1 1 1 0 PilX N-terminal Abhydrolase_6 PF12697.2 OAJ30906.1 - 1.3e-24 87.4 0.2 1.3e-24 87.4 0.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ30906.1 - 4.7e-15 55.7 1.4 2e-09 37.3 0.1 2.5 2 1 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ30906.1 - 3.1e-08 33.4 0.1 5.7e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 OAJ30906.1 - 5.4e-05 21.8 0.0 7e-05 21.4 0.0 1.1 1 0 0 1 1 1 1 Ndr family Esterase PF00756.15 OAJ30906.1 - 6.6e-05 22.4 0.0 0.00013 21.5 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 OAJ30906.1 - 0.0021 17.5 0.1 0.061 12.7 0.0 2.1 1 1 0 2 2 2 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 OAJ30906.1 - 0.021 14.6 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase GTP_cyclohydroI PF01227.17 OAJ30907.1 - 4e-75 251.0 0.1 6.4e-75 250.3 0.1 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 OAJ30907.1 - 0.001 18.9 0.0 0.0031 17.4 0.0 1.8 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 OAJ30907.1 - 0.015 15.0 0.1 0.044 13.5 0.1 1.8 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain NCD2 PF04905.8 OAJ30907.1 - 0.49 10.1 0.0 0.49 10.1 0.0 2.2 2 0 0 2 2 2 0 NAB conserved region 2 (NCD2) BolA PF01722.13 OAJ30908.1 - 1.4e-15 57.0 0.0 2.1e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein HA2 PF04408.18 OAJ30909.1 - 7.2e-20 70.9 0.0 5.7e-19 68.0 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ30909.1 - 7.4e-13 48.1 0.1 7.3e-12 44.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 OAJ30909.1 - 1.9e-11 43.8 0.0 5.7e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 OAJ30909.1 - 2e-06 27.3 0.0 5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ30909.1 - 0.00093 19.3 0.0 0.0033 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 OAJ30909.1 - 0.0032 17.8 5.8 0.23 11.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain KaiC PF06745.8 OAJ30909.1 - 0.025 13.7 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 KaiC Pyr_redox_2 PF07992.9 OAJ30910.1 - 2.2e-11 44.0 1.8 2.9e-10 40.3 1.3 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ30910.1 - 9.1e-09 35.6 1.5 2e-07 31.3 0.0 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAJ30910.1 - 1.3e-08 35.1 3.5 5.4e-05 23.3 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ30910.1 - 1.5e-06 27.4 1.7 2.8e-05 23.2 0.1 2.8 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 OAJ30910.1 - 1.9e-05 24.8 3.9 0.0041 17.3 0.1 3.3 3 1 0 3 3 3 1 Putative NAD(P)-binding TrkA_N PF02254.13 OAJ30910.1 - 6.2e-05 22.9 0.9 0.31 11.0 0.0 3.0 3 0 0 3 3 3 2 TrkA-N domain Trp_halogenase PF04820.9 OAJ30910.1 - 0.00045 18.9 1.1 0.0052 15.4 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.19 OAJ30910.1 - 0.001 18.0 3.4 0.031 13.1 0.1 3.2 4 0 0 4 4 4 1 FAD dependent oxidoreductase ThiF PF00899.16 OAJ30910.1 - 0.0011 18.7 2.1 0.31 10.8 0.0 3.6 4 0 0 4 4 4 1 ThiF family NAD_binding_9 PF13454.1 OAJ30910.1 - 0.003 17.3 2.3 2.5 7.8 0.0 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 OAJ30910.1 - 0.0031 17.5 0.9 0.63 10.1 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 OAJ30910.1 - 0.0035 16.3 1.1 0.97 8.2 0.1 2.4 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAJ30910.1 - 0.0065 16.4 0.1 0.029 14.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Abhydrolase_6 PF12697.2 OAJ30910.1 - 0.0073 16.2 0.1 0.021 14.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 OAJ30910.1 - 0.065 12.2 0.3 2.6 7.0 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain Abhydrolase_5 PF12695.2 OAJ30910.1 - 0.11 12.3 3.8 0.45 10.2 0.1 2.4 1 1 0 2 2 2 0 Alpha/beta hydrolase family NDK PF00334.14 OAJ30911.1 - 1.2e-50 170.7 0.0 1.6e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase SIS PF01380.17 OAJ30911.1 - 0.021 14.4 0.1 5.2 6.6 0.0 2.7 2 1 1 3 3 3 0 SIS domain Herpes_capsid PF06112.6 OAJ30911.1 - 0.11 12.5 3.3 0.17 11.9 2.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ADH_zinc_N PF00107.21 OAJ30912.1 - 0.00045 19.7 0.0 0.00093 18.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ30912.1 - 0.032 13.9 0.0 0.16 11.7 0.0 2.0 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 OAJ30912.1 - 0.09 13.6 0.0 0.39 11.5 0.0 2.1 2 1 1 3 3 3 0 Zinc-binding dehydrogenase Pkinase PF00069.20 OAJ30913.1 - 7.7e-72 241.5 0.0 8.7e-72 241.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ30913.1 - 1e-33 116.5 0.0 1.3e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ30913.1 - 0.00017 20.6 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ30913.1 - 0.0013 18.5 0.1 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ30913.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 OAJ30913.1 - 0.078 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CRAL_TRIO_2 PF13716.1 OAJ30913.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DnaJ PF00226.26 OAJ30914.1 - 1.7e-22 78.9 0.1 5.4e-22 77.3 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.1 OAJ30914.1 - 2e-19 68.9 13.7 3e-12 46.0 1.2 5.0 3 2 2 5 5 5 5 TPR repeat TPR_19 PF14559.1 OAJ30914.1 - 3.1e-14 53.0 14.5 1.4e-05 25.3 0.1 5.7 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ30914.1 - 3.1e-14 53.1 26.8 4.6e-07 30.3 0.4 5.8 4 3 2 6 6 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ30914.1 - 1.1e-12 46.9 2.0 0.00071 19.0 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ30914.1 - 1.4e-12 46.4 13.0 0.014 15.2 0.7 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ30914.1 - 1.2e-11 43.8 0.5 0.023 14.8 0.0 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ30914.1 - 3.2e-10 39.6 18.8 0.049 14.2 0.1 6.4 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ30914.1 - 3.3e-09 36.4 10.4 1.9e-05 24.4 0.4 4.8 3 2 1 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 OAJ30914.1 - 3e-06 27.2 4.3 0.04 14.0 0.1 3.8 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 OAJ30914.1 - 0.00018 21.0 1.2 13 5.8 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ30914.1 - 0.021 14.9 11.9 1.7 8.8 0.2 4.8 2 1 2 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.12 OAJ30914.1 - 0.032 14.5 16.8 0.092 13.0 0.9 4.1 3 1 1 4 4 4 0 Bacterial transcriptional activator domain TPR_12 PF13424.1 OAJ30914.1 - 0.074 13.0 13.3 2.8 7.9 0.2 4.3 3 2 1 4 4 3 0 Tetratricopeptide repeat RPT PF13446.1 OAJ30914.1 - 0.074 12.4 0.0 3.1 7.2 0.0 2.6 2 0 0 2 2 2 0 A repeated domain in UCH-protein DUF4603 PF15376.1 OAJ30914.1 - 0.11 9.6 4.4 0.19 8.8 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Cytochrom_B562 PF07361.6 OAJ30914.1 - 0.71 10.3 7.7 1.3 9.4 0.1 3.9 4 0 0 4 4 3 0 Cytochrome b562 Fis1_TPR_C PF14853.1 OAJ30914.1 - 0.84 9.5 5.4 4.5 7.2 0.1 4.2 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 OAJ30914.1 - 1.6 8.6 7.4 11 6.0 0.1 4.3 5 0 0 5 5 2 0 Tetratricopeptide repeat Pex19 PF04614.7 OAJ30914.1 - 3 7.4 7.9 0.69 9.4 2.5 1.9 2 0 0 2 2 2 0 Pex19 protein family TPR_6 PF13174.1 OAJ30914.1 - 4 8.0 17.9 6.6 7.4 0.0 7.1 9 1 0 9 9 7 0 Tetratricopeptide repeat Abhydro_lipase PF04083.11 OAJ30915.1 - 2.8e-15 55.3 0.0 5.4e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 OAJ30915.1 - 8.7e-06 25.7 0.9 2.2e-05 24.4 0.7 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ30915.1 - 0.00034 20.2 0.1 0.0013 18.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ30915.1 - 0.00073 19.3 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COX4 PF02936.9 OAJ30916.1 - 6.1e-30 103.8 0.0 1.2e-29 102.8 0.0 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase subunit IV Pkinase PF00069.20 OAJ30917.1 - 5.4e-73 245.3 0.0 6.1e-73 245.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ30917.1 - 4.4e-32 111.1 0.0 5.7e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ30917.1 - 7.6e-06 25.0 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ30917.1 - 0.0018 18.0 0.1 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ30917.1 - 0.012 14.4 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DSBA PF01323.15 OAJ30918.1 - 2.3e-24 86.0 0.0 3.1e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Formyl_trans_N PF00551.14 OAJ30919.1 - 2.4e-20 72.8 0.0 3.1e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 OAJ30919.1 - 1e-06 28.7 0.0 2.4e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Formyl transferase, C-terminal domain DKCLD PF08068.7 OAJ30920.1 - 1.8e-29 101.4 0.1 5.7e-29 99.8 0.1 1.8 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 OAJ30920.1 - 2.2e-24 86.3 0.2 3.6e-21 75.9 0.1 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 OAJ30920.1 - 2.2e-19 68.9 0.7 4.8e-19 67.8 0.5 1.6 1 0 0 1 1 1 1 PUA domain Ima1_N PF09779.4 OAJ30921.1 - 6.2e-20 72.0 0.3 6.2e-20 72.0 0.2 1.8 2 0 0 2 2 2 1 Ima1 N-terminal domain Sporozoite_P67 PF05642.6 OAJ30921.1 - 0.038 11.8 10.2 0.056 11.3 7.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.6 OAJ30921.1 - 0.5 8.2 9.6 0.85 7.5 6.7 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Methyltransf_26 PF13659.1 OAJ30922.1 - 1.9e-10 40.8 0.0 3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ30922.1 - 1.8e-06 27.4 0.0 0.00016 21.0 0.0 2.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 OAJ30922.1 - 0.03 14.6 0.0 0.068 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 OAJ30922.1 - 0.074 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 OAJ30922.1 - 0.13 12.7 0.0 0.3 11.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain CmcI PF04989.7 OAJ30922.1 - 0.18 11.0 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase tRNA-synt_2 PF00152.15 OAJ30924.1 - 2.5e-78 263.2 0.2 4.3e-78 262.4 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAJ30924.1 - 1.9e-05 24.4 0.0 3.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 OAJ30924.1 - 0.031 13.4 0.5 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) PcfJ PF14284.1 OAJ30924.1 - 0.57 9.6 5.4 11 5.4 1.4 2.5 2 1 0 2 2 2 0 PcfJ-like protein NIF PF03031.13 OAJ30925.1 - 4.3e-19 68.7 0.0 1.3e-16 60.6 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 OAJ30925.1 - 2.6e-09 36.7 0.0 4.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 OAJ30925.1 - 7.7e-07 29.1 0.0 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BUD22 PF09073.5 OAJ30925.1 - 0.0034 16.5 2.7 0.0034 16.5 1.9 3.5 3 1 0 3 3 3 1 BUD22 Abhydrolase_6 PF12697.2 OAJ30926.1 - 1.9e-17 63.9 0.8 2e-16 60.5 0.6 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ30926.1 - 2.7e-16 59.6 0.0 7.2e-16 58.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ30926.1 - 4.9e-11 42.3 0.0 9.1e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 OAJ30926.1 - 1.8e-06 27.6 1.0 0.00032 20.3 0.6 3.3 3 1 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 OAJ30926.1 - 7.6e-05 22.2 0.0 0.0015 17.9 0.0 2.7 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Ribosomal_L22e PF01776.12 OAJ30928.1 - 1.2e-45 154.0 0.0 1.4e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family SNF2_N PF00176.18 OAJ30929.1 - 2.8e-64 216.7 0.0 4.3e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ30929.1 - 3.3e-15 55.6 0.0 7.1e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ30929.1 - 3.8e-05 23.2 0.0 0.0001 21.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ30929.1 - 0.00018 21.4 0.0 0.00073 19.4 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.1 OAJ30929.1 - 0.00053 19.5 10.8 0.0011 18.6 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ30929.1 - 0.0007 19.2 13.8 0.0014 18.2 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ30929.1 - 0.00077 19.4 15.2 0.0015 18.5 10.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ30929.1 - 0.003 17.3 13.0 0.0062 16.3 9.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAJ30929.1 - 0.034 13.8 14.2 0.067 12.9 9.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DEAD_2 PF06733.10 OAJ30929.1 - 0.039 13.3 0.1 0.16 11.3 0.1 1.9 1 1 0 1 1 1 0 DEAD_2 Pol_alpha_B_N PF08418.5 OAJ30931.1 - 9.5 5.6 7.9 12 5.2 5.5 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RTC4 PF14474.1 OAJ30934.1 - 3.4e-11 43.1 0.0 5.4e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain SBF PF01758.11 OAJ30934.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Sodium Bile acid symporter family SDA1 PF05285.7 OAJ30935.1 - 0.00037 19.8 9.5 0.00041 19.7 6.6 1.2 1 0 0 1 1 1 1 SDA1 Daxx PF03344.10 OAJ30935.1 - 0.0032 16.0 14.0 0.0035 15.8 9.7 1.1 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 OAJ30935.1 - 0.011 13.7 17.5 0.014 13.3 12.1 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 OAJ30935.1 - 0.093 11.7 12.4 0.1 11.6 8.6 1.1 1 0 0 1 1 1 0 BUD22 DUF1510 PF07423.6 OAJ30935.1 - 0.54 9.5 12.9 0.76 9.1 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 OAJ30935.1 - 2.1 6.3 13.3 2.5 6.0 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.1 OAJ30935.1 - 2.3 7.7 14.6 3.9 7.0 10.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pox_Ag35 PF03286.9 OAJ30935.1 - 2.5 7.5 8.4 4.6 6.7 5.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein eIF-3c_N PF05470.7 OAJ30935.1 - 9.8 4.1 6.8 12 3.8 4.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RVT_2 PF07727.9 OAJ30936.1 - 7.6e-82 273.9 0.0 1e-81 273.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ30936.1 - 1.5e-26 92.8 0.0 3.2e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ30936.1 - 0.00015 21.1 0.0 0.00047 19.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ30936.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) NPR1_like_C PF12313.3 OAJ30936.1 - 0.16 11.4 0.0 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 NPR1/NIM1 like defence protein C terminal UBN2 PF14223.1 OAJ30937.1 - 1.8e-06 27.7 0.2 2.8e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ30937.1 - 6.4e-06 25.8 6.7 1e-05 25.1 4.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ30937.1 - 0.01 15.5 1.4 0.021 14.5 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle UBN2_2 PF14227.1 OAJ30937.1 - 0.012 15.1 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type LON PF02190.11 OAJ30938.1 - 1.5e-24 86.8 0.0 1.9e-23 83.2 0.0 2.1 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 OAJ30938.1 - 1.5e-12 47.3 21.6 3.7e-07 30.0 6.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ30938.1 - 3e-11 42.9 19.6 6.7e-07 29.0 7.0 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_4 PF15227.1 OAJ30938.1 - 1.2e-09 37.8 21.6 8.4e-06 25.5 3.0 2.5 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 OAJ30938.1 - 2.8e-09 36.4 17.1 5.2e-06 26.0 3.6 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ30938.1 - 3.8e-09 36.0 21.1 4.9e-05 22.9 5.8 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ30938.1 - 4.3e-09 35.9 19.3 2.1e-05 24.1 5.6 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_6 PF14835.1 OAJ30938.1 - 0.00015 21.4 11.6 0.035 13.8 1.2 2.5 2 0 0 2 2 2 2 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 OAJ30938.1 - 0.0021 17.6 3.6 0.0021 17.6 2.5 3.0 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 OAJ30938.1 - 0.0029 17.2 16.9 0.075 12.7 3.0 2.6 2 0 0 2 2 2 2 RING-type zinc-finger Prok-RING_4 PF14447.1 OAJ30938.1 - 0.13 11.8 13.6 0.32 10.5 4.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 CLTH PF10607.4 OAJ30939.1 - 1.1e-17 64.0 0.0 5.4e-17 61.8 0.0 1.9 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Gly_kinase PF02595.10 OAJ30939.1 - 0.013 14.1 0.5 0.047 12.3 0.0 1.9 2 0 0 2 2 2 0 Glycerate kinase family Kelch_4 PF13418.1 OAJ30940.1 - 1.2e-13 50.6 3.3 0.0019 17.9 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 OAJ30940.1 - 5.4e-12 45.3 2.1 0.097 12.8 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 OAJ30940.1 - 9e-09 35.2 6.6 0.00037 20.5 0.1 6.4 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 OAJ30940.1 - 1.2e-07 31.1 0.1 0.01 15.3 0.0 3.7 3 1 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 OAJ30940.1 - 1.2e-07 31.5 0.5 0.00016 21.5 0.0 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 OAJ30940.1 - 0.00011 21.7 0.3 0.0096 15.6 0.0 3.6 2 0 0 2 2 2 1 Kelch motif DUF3712 PF12505.3 OAJ30941.1 - 1.1e-108 358.2 44.4 8.9e-23 80.6 0.1 8.4 8 0 0 8 8 8 6 Protein of unknown function (DUF3712) LEA_2 PF03168.8 OAJ30941.1 - 1.8e-10 41.1 17.1 0.046 14.0 0.1 9.3 10 0 0 10 10 10 4 Late embryogenesis abundant protein EF1_GNE PF00736.14 OAJ30942.1 - 1.8e-29 101.2 2.2 3.2e-29 100.4 1.5 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 OAJ30942.1 - 6.6e-11 42.1 6.6 6.6e-11 42.1 4.5 2.6 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 OAJ30942.1 - 3e-05 24.4 0.0 6.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ30942.1 - 0.00011 22.0 0.3 0.0012 18.6 0.2 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAJ30942.1 - 0.0013 18.6 0.3 0.004 17.1 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.7 OAJ30942.1 - 0.015 15.0 2.6 0.021 14.5 1.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 OAJ30942.1 - 0.31 10.4 5.5 0.39 10.1 3.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4355 PF14265.1 OAJ30943.1 - 4.4 7.2 18.1 16 5.4 12.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) F-box-like PF12937.2 OAJ30944.1 - 4.3e-05 23.1 0.5 0.00039 20.0 0.4 2.3 1 1 0 1 1 1 1 F-box-like START PF01852.14 OAJ30945.1 - 0.001 18.4 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 START domain PCI PF01399.22 OAJ30946.1 - 8.6e-08 32.4 0.1 2.5e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 OAJ30946.1 - 0.092 12.7 0.1 0.28 11.1 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Abi PF02517.11 OAJ30947.1 - 2e-15 56.6 4.7 2e-15 56.6 3.3 2.6 3 1 0 3 3 3 1 CAAX protease self-immunity Inositol_P PF00459.20 OAJ30948.1 - 1.8e-60 204.5 0.0 2.1e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family p450 PF00067.17 OAJ30949.1 - 1.8e-42 145.4 0.0 7.3e-25 87.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Ribonuclease_3 PF00636.21 OAJ30950.1 - 9.2e-38 129.1 0.0 2.9e-19 69.6 0.0 3.0 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 OAJ30950.1 - 1.4e-20 73.5 6.1 3.3e-12 46.4 0.2 3.7 3 1 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.26 OAJ30950.1 - 5.3e-14 51.8 0.0 1.4e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 OAJ30950.1 - 1.1e-12 47.4 0.1 3.1e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.24 OAJ30950.1 - 5.1e-08 32.5 0.0 1.3e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ30950.1 - 7.6e-08 32.3 0.0 2e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 OAJ30950.1 - 0.0036 17.8 0.0 0.04 14.4 0.0 2.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif SNF2_N PF00176.18 OAJ30950.1 - 0.051 12.3 0.0 0.12 11.1 0.0 1.6 1 0 0 1 1 1 0 SNF2 family N-terminal domain PALP PF00291.20 OAJ30951.1 - 2.2e-42 145.3 0.0 3.4e-40 138.1 0.0 2.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1049 PF06305.6 OAJ30951.1 - 0.0043 16.4 1.5 0.037 13.5 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1049) ADH_zinc_N PF00107.21 OAJ30951.1 - 0.053 13.0 0.0 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Tim17 PF02466.14 OAJ30951.1 - 0.18 11.8 2.4 12 5.9 0.2 2.3 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family F-box-like PF12937.2 OAJ30952.1 - 6.1e-12 45.0 0.0 6.1e-12 45.0 0.0 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 OAJ30952.1 - 4.9e-08 32.4 0.0 4.9e-08 32.4 0.0 2.5 3 0 0 3 3 3 1 F-box domain PQQ_2 PF13360.1 OAJ30952.1 - 2.2e-05 24.0 0.2 0.0026 17.2 0.1 2.3 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 OAJ30952.1 - 8.4e-05 21.9 1.5 0.43 10.2 0.0 3.0 3 0 0 3 3 3 2 PQQ enzyme repeat RXT2_N PF08595.6 OAJ30952.1 - 0.036 13.8 1.9 9.2 6.0 1.7 2.3 1 1 1 2 2 2 0 RXT2-like, N-terminal DUF4175 PF13779.1 OAJ30953.1 - 2 6.0 16.1 2.2 5.8 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3432 PF11914.3 OAJ30953.1 - 5.8 7.0 18.8 9.4 6.3 13.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) DUF605 PF04652.11 OAJ30953.1 - 5.9 6.1 20.3 8.3 5.6 14.1 1.1 1 0 0 1 1 1 0 Vta1 like ABC_membrane PF00664.18 OAJ30955.1 - 7.7e-57 192.7 28.6 2e-29 102.8 10.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ30955.1 - 2.5e-54 183.3 0.0 5.3e-31 107.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 OAJ30955.1 - 3.7e-09 36.9 0.1 0.18 11.7 0.0 4.3 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 OAJ30955.1 - 2.7e-07 30.0 2.5 0.014 14.6 0.0 3.9 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 OAJ30955.1 - 5.9e-07 29.0 0.3 0.064 12.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 OAJ30955.1 - 7.5e-07 28.5 0.2 0.0013 18.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 OAJ30955.1 - 4.8e-06 26.5 0.7 0.0063 16.4 0.1 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 OAJ30955.1 - 5.1e-06 26.9 5.2 0.19 12.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 OAJ30955.1 - 1.3e-05 25.6 1.5 0.035 14.6 0.1 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_16 PF13191.1 OAJ30955.1 - 2.9e-05 24.1 8.6 0.05 13.5 0.1 3.7 2 1 1 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 OAJ30955.1 - 7.2e-05 22.0 0.2 0.33 10.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 OAJ30955.1 - 9.3e-05 22.0 0.1 0.054 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain T2SE PF00437.15 OAJ30955.1 - 0.00014 20.8 0.0 0.0084 15.0 0.0 2.6 3 0 0 3 3 2 1 Type II/IV secretion system protein AAA_17 PF13207.1 OAJ30955.1 - 0.00022 22.0 0.3 0.2 12.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 OAJ30955.1 - 0.0005 19.9 0.6 0.0016 18.3 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_14 PF13173.1 OAJ30955.1 - 0.0013 18.6 0.2 15 5.5 0.0 4.1 4 0 0 4 4 4 0 AAA domain Zeta_toxin PF06414.7 OAJ30955.1 - 0.0015 17.6 0.6 0.4 9.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.9 OAJ30955.1 - 0.002 17.8 1.2 0.3 10.7 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 OAJ30955.1 - 0.0021 18.1 0.8 2.1 8.5 0.0 3.2 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 OAJ30955.1 - 0.006 16.2 1.3 3.1 7.4 0.1 2.6 2 0 0 2 2 2 2 NACHT domain Dynamin_N PF00350.18 OAJ30955.1 - 0.0066 16.2 5.1 0.086 12.6 0.0 3.0 3 0 0 3 3 3 1 Dynamin family FtsK_SpoIIIE PF01580.13 OAJ30955.1 - 0.013 15.0 0.2 0.053 12.9 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 OAJ30955.1 - 0.016 15.0 1.4 8.1 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 OAJ30955.1 - 0.049 13.0 1.8 1.9 7.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 OAJ30955.1 - 0.055 13.7 2.8 0.75 10.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 OAJ30955.1 - 0.07 13.3 0.1 13 5.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase TrwB_AAD_bind PF10412.4 OAJ30955.1 - 0.079 11.5 1.0 0.61 8.6 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.17 OAJ30955.1 - 0.083 11.7 0.5 5.5 5.7 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.20 OAJ30955.1 - 0.11 11.9 0.1 6.8 6.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 OAJ30955.1 - 0.12 12.1 4.1 0.71 9.5 0.0 3.3 5 1 0 5 5 2 0 Archaeal ATPase Adeno_IVa2 PF02456.10 OAJ30955.1 - 0.17 10.4 0.0 6.9 5.2 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA PF00004.24 OAJ30955.1 - 0.2 11.8 1.3 22 5.2 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 OAJ30955.1 - 0.2 11.2 1.2 9.1 5.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 OAJ30955.1 - 0.37 10.2 0.7 18 4.8 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.4 OAJ30955.1 - 0.4 9.1 3.3 9.3 4.7 0.1 3.6 4 0 0 4 4 4 0 Predicted ATPase of the ABC class Viral_helicase1 PF01443.13 OAJ30955.1 - 0.46 9.9 0.5 13 5.2 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DIM PF08194.7 OAJ30955.1 - 3.5 7.6 5.0 1.4 8.9 0.4 2.7 2 0 0 2 2 1 0 DIM protein Acyl-CoA_dh_1 PF00441.19 OAJ30956.1 - 1.4e-27 96.6 2.6 2.2e-27 96.0 1.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 OAJ30956.1 - 1.8e-14 54.1 3.7 1.8e-14 54.1 2.6 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ30956.1 - 3.2e-13 48.9 0.0 6.8e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 OAJ30956.1 - 4.7e-10 40.0 0.0 9.7e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain CPSase_L_D2 PF02786.12 OAJ30957.1 - 6e-83 277.2 0.1 1e-82 276.5 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 OAJ30957.1 - 2.8e-68 229.2 0.0 7.1e-68 227.9 0.0 1.7 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 OAJ30957.1 - 3.7e-36 123.5 0.3 1.9e-35 121.2 0.0 2.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 OAJ30957.1 - 5.4e-31 106.7 0.0 1.1e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 OAJ30957.1 - 3.8e-29 102.0 0.0 7.6e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 OAJ30957.1 - 2e-18 66.8 0.2 3.5e-18 65.9 0.2 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAJ30957.1 - 9.6e-18 64.0 0.1 3.6e-17 62.1 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 OAJ30957.1 - 1.3e-14 53.5 0.8 2.5e-14 52.6 0.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 OAJ30957.1 - 2.1e-12 46.5 0.8 5e-05 22.8 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 OAJ30957.1 - 7.4e-11 41.8 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 OAJ30957.1 - 5.2e-07 29.1 0.0 1.1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 OAJ30957.1 - 6.5e-07 28.9 0.3 0.0052 16.1 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein RimK PF08443.6 OAJ30957.1 - 4.9e-06 26.1 0.0 1.3e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 OAJ30957.1 - 1.9e-05 24.5 0.0 4.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 OAJ30957.1 - 0.0023 18.2 0.2 1.9 8.8 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein GARS_A PF01071.14 OAJ30957.1 - 0.0063 16.0 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SAE2 PF08573.5 OAJ30958.1 - 9.6e-12 45.4 2.2 9.6e-12 45.4 1.5 3.6 2 2 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus SBP_bac_7 PF03480.8 OAJ30958.1 - 0.015 14.3 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 DUF3366 PF11846.3 OAJ30958.1 - 0.066 13.0 0.8 0.13 12.1 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) AF1Q PF15017.1 OAJ30958.1 - 3 7.7 6.2 0.66 9.9 1.2 2.2 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Cyclase PF04199.8 OAJ30959.1 - 2.8e-13 49.9 0.0 5.3e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Putative cyclase Imm8 PF15560.1 OAJ30960.1 - 0.024 14.3 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 8 Syntaxin_2 PF14523.1 OAJ30960.1 - 0.056 13.4 0.7 0.29 11.1 0.1 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Transposase_21 PF02992.9 OAJ30961.1 - 0.0002 20.5 0.0 0.00042 19.4 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 RVT_2 PF07727.9 OAJ30962.1 - 3.9e-49 166.8 0.0 4.9e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 OAJ30962.1 - 0.019 14.7 0.0 0.12 12.2 0.0 2.3 3 0 0 3 3 3 0 Reverse transcriptase-like Cys_Met_Meta_PP PF01053.15 OAJ30963.1 - 1.7e-58 197.8 0.0 1.9e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Cwf_Cwc_15 PF04889.7 OAJ30964.1 - 0.055 13.1 17.8 0.025 14.2 4.4 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.9 OAJ30964.1 - 0.15 11.5 16.2 0.15 11.5 3.5 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DDHD PF02862.12 OAJ30964.1 - 0.24 11.1 10.1 0.24 11.1 0.9 2.2 2 0 0 2 2 2 0 DDHD domain DUF1754 PF08555.5 OAJ30964.1 - 2.4 8.8 23.0 0.42 11.2 7.9 2.7 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) NOA36 PF06524.7 OAJ30964.1 - 7.4 5.7 11.1 14 4.8 7.7 1.4 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.5 OAJ30964.1 - 9.5 5.1 29.3 16 4.4 20.3 1.4 1 1 0 1 1 1 0 BUD22 Ribosomal_60s PF00428.14 OAJ30965.1 - 5.4 7.4 13.2 1.9 8.9 6.8 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_L13e PF01294.13 OAJ30966.1 - 1.5e-59 200.4 7.0 2e-59 200.0 4.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Acetyltransf_1 PF00583.19 OAJ30967.1 - 1.6e-10 40.8 0.2 0.00012 21.9 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ30967.1 - 3.8e-05 23.7 0.0 0.21 11.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ30967.1 - 9.5e-05 22.0 0.1 0.11 12.2 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_10 PF13673.1 OAJ30967.1 - 0.0012 18.9 0.0 0.94 9.6 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 OAJ30967.1 - 0.03 14.2 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAJ30967.1 - 0.044 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1880 PF08976.6 OAJ30968.1 - 6 7.0 6.0 0.97 9.5 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1880) DUF3419 PF11899.3 OAJ30970.1 - 9.7e-16 57.4 0.0 1.2e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Ribonuclease PF00545.15 OAJ30970.1 - 2.3e-08 34.0 0.9 4e-08 33.2 0.3 1.6 2 0 0 2 2 2 1 ribonuclease DUF3419 PF11899.3 OAJ30971.1 - 2e-135 451.4 0.0 2.6e-135 450.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 OAJ30971.1 - 1.6e-10 40.8 0.0 2.4e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ30971.1 - 5.4e-08 32.5 0.0 1.2e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ30971.1 - 2.6e-07 30.0 0.0 4.1e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 OAJ30971.1 - 7.5e-07 29.5 0.0 0.00024 21.5 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ30971.1 - 7.2e-06 26.3 0.0 2.6e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ30971.1 - 1.6e-05 25.2 0.0 5e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ30971.1 - 2.1e-05 25.0 0.0 6.3e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ30971.1 - 0.00055 19.9 0.1 0.061 13.3 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain DnaJ PF00226.26 OAJ30972.1 - 1.8e-18 65.9 0.2 3.2e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DHH PF01368.15 OAJ30972.1 - 1.2e-05 24.9 0.0 4.7e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 DHH family Zip PF02535.17 OAJ30972.1 - 0.052 12.5 0.6 0.064 12.2 0.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Rib_recp_KP_reg PF05104.7 OAJ30972.1 - 3.4 8.1 7.1 8.9 6.8 4.9 1.7 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region MRP-L27 PF09809.4 OAJ30974.1 - 1.4e-06 27.9 0.4 2.8e-05 23.7 0.2 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 BING4CT PF08149.6 OAJ30976.1 - 2.9e-34 116.4 0.0 6.6e-33 112.0 0.0 3.0 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.27 OAJ30976.1 - 3.6e-07 29.8 0.0 3.9e-05 23.3 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 OAJ30976.1 - 0.00041 19.2 0.0 0.0006 18.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region MAGE PF01454.14 OAJ30977.1 - 8.1e-19 67.7 0.0 6.7e-15 54.9 0.0 2.7 2 0 0 2 2 2 2 MAGE family ABC_tran PF00005.22 OAJ30978.1 - 4.3e-47 159.8 0.2 4.2e-23 82.1 0.0 2.9 4 0 0 4 4 2 2 ABC transporter AAA_21 PF13304.1 OAJ30978.1 - 6.2e-21 75.6 1.7 0.00012 22.2 0.0 4.3 3 1 1 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 OAJ30978.1 - 7.5e-20 70.5 4.4 7.5e-20 70.5 3.0 2.2 2 0 0 2 2 1 1 ABC transporter AAA_23 PF13476.1 OAJ30978.1 - 7e-10 39.5 5.7 0.0015 18.8 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 OAJ30978.1 - 6e-09 35.3 0.2 0.0036 16.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 OAJ30978.1 - 1.2e-08 34.5 2.2 0.27 10.4 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 OAJ30978.1 - 1.2e-06 28.6 0.0 0.015 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 OAJ30978.1 - 4e-06 27.6 0.0 0.2 12.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 OAJ30978.1 - 4.4e-06 27.1 0.0 0.18 12.2 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 OAJ30978.1 - 3.3e-05 24.0 0.2 0.046 13.8 0.0 3.5 3 1 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 OAJ30978.1 - 3.4e-05 23.7 0.2 0.035 14.0 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 OAJ30978.1 - 8e-05 22.5 2.6 0.84 9.4 0.0 4.1 4 1 0 4 4 4 2 Dynamin family AAA_28 PF13521.1 OAJ30978.1 - 8.7e-05 22.5 0.0 0.33 10.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 OAJ30978.1 - 0.00017 20.8 11.3 0.073 12.1 0.0 4.7 4 2 0 4 4 4 1 AAA ATPase domain DUF258 PF03193.11 OAJ30978.1 - 0.00019 20.6 0.0 0.05 12.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 OAJ30978.1 - 0.00032 20.5 0.0 0.28 11.1 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 OAJ30978.1 - 0.00034 20.3 0.5 0.14 11.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 OAJ30978.1 - 0.00057 20.2 1.4 0.64 10.3 0.0 3.2 4 0 0 4 4 3 1 AAA domain T2SE PF00437.15 OAJ30978.1 - 0.001 18.0 0.0 0.32 9.8 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.1 OAJ30978.1 - 0.0011 18.8 0.0 1.5 8.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 OAJ30978.1 - 0.0015 18.2 3.5 1.1 8.9 0.1 3.5 3 1 1 4 4 3 2 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 OAJ30978.1 - 0.0015 18.0 0.1 2.3 7.6 0.0 2.8 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_25 PF13481.1 OAJ30978.1 - 0.0022 17.4 0.0 0.96 8.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.17 OAJ30978.1 - 0.0027 16.6 0.1 0.68 8.7 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain ArgK PF03308.11 OAJ30978.1 - 0.003 16.3 0.0 0.44 9.2 0.0 2.8 3 0 0 3 3 3 1 ArgK protein AAA_10 PF12846.2 OAJ30978.1 - 0.0052 16.2 0.2 4.6 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 OAJ30978.1 - 0.0055 16.6 0.2 12 5.7 0.1 4.0 3 1 0 3 3 3 0 AAA domain cobW PF02492.14 OAJ30978.1 - 0.0055 16.1 1.0 0.81 9.1 0.0 2.8 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 OAJ30978.1 - 0.0059 16.7 0.4 1.3 9.2 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 OAJ30978.1 - 0.012 15.8 1.1 7.5 6.7 0.1 3.1 3 0 0 3 3 3 0 RNA helicase FeoB_N PF02421.13 OAJ30978.1 - 0.014 14.6 0.0 0.47 9.7 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B NTPase_1 PF03266.10 OAJ30978.1 - 0.023 14.3 3.2 12 5.5 0.1 3.6 4 0 0 4 4 4 0 NTPase AAA_5 PF07728.9 OAJ30978.1 - 0.036 13.7 0.9 8.3 6.1 0.1 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 OAJ30978.1 - 0.041 13.4 5.6 1.7 8.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 OAJ30978.1 - 0.049 13.1 0.0 4.9 6.5 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.12 OAJ30978.1 - 0.14 11.9 5.6 3.7 7.3 0.0 3.7 4 1 1 5 5 4 0 Domain of unknown function DUF87 Arm PF00514.18 OAJ30979.1 - 3.7e-95 308.9 13.0 7.1e-14 51.0 0.0 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 OAJ30979.1 - 1.6e-24 85.9 0.6 3.2e-08 33.7 0.0 6.6 1 1 6 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 OAJ30979.1 - 1.2e-23 82.8 3.9 6e-09 36.1 0.0 6.5 5 1 2 7 7 7 4 HEAT-like repeat HEAT PF02985.17 OAJ30979.1 - 1.2e-18 65.4 3.8 7.6e-05 22.4 0.0 7.8 7 0 0 7 7 7 3 HEAT repeat IBB PF01749.15 OAJ30979.1 - 3.8e-18 65.4 4.9 8.6e-18 64.3 3.4 1.6 1 0 0 1 1 1 1 Importin beta binding domain Arm_2 PF04826.8 OAJ30979.1 - 5.4e-05 22.4 0.0 0.62 9.1 0.0 3.9 2 1 2 4 4 4 2 Armadillo-like HEAT_PBS PF03130.11 OAJ30979.1 - 6.6e-05 23.0 3.4 0.051 14.0 0.0 5.8 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Adaptin_N PF01602.15 OAJ30979.1 - 0.00054 18.4 0.0 0.0078 14.5 0.0 2.5 1 1 0 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 OAJ30979.1 - 0.0061 16.4 0.1 3.3 7.6 0.0 4.3 3 3 2 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 OAJ30979.1 - 0.0099 14.1 0.0 0.11 10.7 0.0 2.4 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit Vps35 PF03635.12 OAJ30979.1 - 0.12 10.5 0.0 0.22 9.6 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 APG9 PF04109.11 OAJ30980.1 - 8.8e-151 501.9 0.0 1.1e-150 501.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Glyco_hydro_92 PF07971.7 OAJ30981.1 - 8.9e-102 341.2 0.6 1.3e-101 340.7 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Cys_Met_Meta_PP PF01053.15 OAJ30982.1 - 2e-132 441.1 0.0 3.8e-132 440.2 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 OAJ30982.1 - 1.5e-05 23.5 0.0 2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.14 OAJ30982.1 - 0.00012 20.9 0.0 0.00018 20.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 OAJ30982.1 - 0.0098 14.8 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 OAJ30982.1 - 0.014 14.0 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 Allinase DUF2665 PF11654.3 OAJ30984.1 - 5.4e-19 67.4 0.0 7.6e-19 67.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) DUF2934 PF11154.3 OAJ30984.1 - 0.02 14.2 0.3 0.062 12.6 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2934) Spb1_C PF07780.7 OAJ30985.1 - 6.3e-67 225.2 29.2 6.3e-67 225.2 20.3 3.6 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 OAJ30985.1 - 5.7e-53 179.5 0.0 1.4e-52 178.2 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 OAJ30985.1 - 2.2e-41 140.9 9.7 2.2e-41 140.9 6.7 5.3 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) UBN2 PF14223.1 OAJ30986.1 - 9e-06 25.4 0.3 1.8e-05 24.5 0.1 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ30986.1 - 1.2e-05 24.9 1.3 3.7e-05 23.4 0.9 1.9 1 0 0 1 1 1 1 Zinc knuckle UBN2_2 PF14227.1 OAJ30986.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_5 PF14787.1 OAJ30986.1 - 0.079 12.4 2.0 0.21 11.0 0.3 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.1 OAJ30986.1 - 0.16 11.5 0.2 0.42 10.1 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.9 OAJ30987.1 - 1.9e-85 285.7 0.0 2.6e-85 285.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ30987.1 - 6.8e-23 81.0 0.7 3.2e-21 75.6 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ30987.1 - 2e-05 24.1 0.0 5.7e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ30987.1 - 0.0031 16.9 0.4 0.036 13.5 0.3 2.7 1 1 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ30987.1 - 0.041 13.2 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) NPV_P10 PF05531.7 OAJ30988.1 - 0.17 12.1 0.6 0.28 11.4 0.4 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein RVT_2 PF07727.9 OAJ30989.1 - 1.4e-85 286.2 0.0 1.9e-85 285.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ30989.1 - 1e-22 80.4 0.3 4.2e-22 78.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain UBN2 PF14223.1 OAJ30989.1 - 5.6e-06 26.1 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAJ30989.1 - 8e-06 25.4 0.1 2e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ30989.1 - 0.063 12.8 0.0 0.22 11.0 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain UBN2_2 PF14227.1 OAJ30989.1 - 0.13 11.7 0.0 0.61 9.6 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Polysacc_deac_1 PF01522.16 OAJ30990.1 - 2.5e-24 85.2 0.1 8.9e-24 83.4 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase Sporozoite_P67 PF05642.6 OAJ30990.1 - 0.14 10.0 11.5 0.2 9.5 7.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pex14_N PF04695.8 OAJ30990.1 - 0.42 10.6 6.8 1 9.4 1.7 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SSP160 PF06933.6 OAJ30990.1 - 6.2 4.6 23.6 9.4 4.0 16.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Lectin_leg-like PF03388.8 OAJ30991.1 - 8.7e-60 201.7 0.1 1.2e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family DUF3561 PF12084.3 OAJ30991.1 - 0.024 14.4 0.2 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) DUF1517 PF07466.6 OAJ30991.1 - 0.8 8.6 3.1 1.1 8.1 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) FA_hydroxylase PF04116.8 OAJ30992.1 - 1.3e-10 41.6 10.5 1.3e-10 41.6 7.3 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Nup160 PF11715.3 OAJ30993.1 - 2.4e-14 52.4 0.7 2e-10 39.4 0.0 3.1 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Peptidase_S10 PF00450.17 OAJ30994.1 - 1.1e-111 374.0 1.8 1.4e-111 373.6 1.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 OAJ30994.1 - 0.0011 18.9 0.0 0.0094 15.8 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Phasin PF05597.6 OAJ30994.1 - 0.038 13.7 0.9 0.068 12.9 0.6 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Apolipoprotein PF01442.13 OAJ30994.1 - 0.04 13.4 0.4 0.063 12.7 0.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TpcC PF12642.2 OAJ30994.1 - 0.12 11.9 0.1 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Conjugative transposon protein TcpC Pribosyltran_N PF13793.1 OAJ30995.1 - 2.9e-44 149.5 0.3 9.8e-43 144.5 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 OAJ30995.1 - 3.2e-40 137.8 2.0 9.1e-33 113.5 0.1 2.8 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 OAJ30995.1 - 2.6e-11 43.3 0.6 1.8e-10 40.5 0.5 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 OAJ30995.1 - 0.078 12.1 0.1 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase HTH_Tnp_Tc5 PF03221.11 OAJ30996.1 - 1.8e-07 30.8 0.0 4.3e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_4 PF13613.1 OAJ30996.1 - 0.00018 20.9 0.0 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease MarR_2 PF12802.2 OAJ30996.1 - 0.0028 17.3 0.0 0.0066 16.0 0.0 1.6 1 0 0 1 1 1 1 MarR family MarR PF01047.17 OAJ30996.1 - 0.0052 16.4 0.4 0.017 14.8 0.0 2.0 2 0 0 2 2 2 1 MarR family OmpH PF03938.9 OAJ30996.1 - 0.0054 16.6 15.4 0.009 15.9 10.7 1.4 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) HTH_23 PF13384.1 OAJ30996.1 - 0.0056 16.2 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.8 OAJ30996.1 - 0.0065 15.8 0.1 0.011 15.0 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 OAJ30996.1 - 0.01 15.3 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.1 OAJ30996.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_28 PF13518.1 OAJ30996.1 - 0.044 13.7 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 OAJ30996.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Hid1 PF12722.2 OAJ30996.1 - 3 5.4 7.0 4 4.9 4.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.7 OAJ30996.1 - 9.4 6.0 13.6 16 5.2 9.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DEAD PF00270.24 OAJ30998.1 - 1e-13 51.1 0.0 2e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ30998.1 - 3e-07 30.2 0.0 5.4e-05 22.9 0.0 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Polysacc_deac_1 PF01522.16 OAJ31000.1 - 1.6e-22 79.4 0.0 2.8e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF515 PF04415.7 OAJ31000.1 - 2.4 6.3 14.7 3.3 5.8 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) WD40 PF00400.27 OAJ31001.1 - 1.9e-38 128.9 22.8 1.9e-07 30.6 0.0 10.5 11 0 0 11 11 11 6 WD domain, G-beta repeat Utp12 PF04003.7 OAJ31001.1 - 4.4e-15 55.5 0.2 1.6e-07 31.1 0.0 2.6 3 0 0 3 3 3 2 Dip2/Utp12 Family PQQ_2 PF13360.1 OAJ31001.1 - 0.0023 17.4 0.0 0.048 13.1 0.0 2.8 1 1 1 2 2 2 1 PQQ-like domain Nup160 PF11715.3 OAJ31001.1 - 0.0028 15.8 0.0 5.2 5.0 0.0 3.5 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 OAJ31001.1 - 0.0063 14.8 0.1 1 7.5 0.0 3.5 4 1 0 4 4 4 1 Cytochrome D1 heme domain DUF1513 PF07433.6 OAJ31001.1 - 0.0089 14.9 0.2 0.48 9.2 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1513) PQQ PF01011.16 OAJ31001.1 - 0.029 13.9 0.2 3.4 7.3 0.0 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat NUDIX PF00293.23 OAJ31003.1 - 0.00055 19.5 0.0 0.00097 18.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.20 OAJ31004.1 - 5.2e-07 29.0 0.1 1.5e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Seadorna_VP7 PF07387.6 OAJ31004.1 - 0.00035 19.4 0.0 0.00052 18.9 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 OAJ31004.1 - 0.00038 20.2 0.0 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ31004.1 - 0.046 12.7 3.7 0.079 12.0 2.6 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ31004.1 - 0.21 10.5 0.0 0.39 9.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Zip PF02535.17 OAJ31004.1 - 8.8 5.2 9.8 6.9 5.5 0.5 2.6 2 0 0 2 2 2 0 ZIP Zinc transporter Transaldolase PF00923.14 OAJ31007.1 - 9.2e-98 326.8 0.3 1.1e-97 326.7 0.2 1.0 1 0 0 1 1 1 1 Transaldolase Imm31 PF15595.1 OAJ31007.1 - 0.069 12.9 0.1 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Immunity protein 31 Aminotran_1_2 PF00155.16 OAJ31008.1 - 1.3e-80 271.0 0.0 1.5e-80 270.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SCP2 PF02036.12 OAJ31009.1 - 6.5e-26 90.5 1.0 7.3e-26 90.4 0.7 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 OAJ31009.1 - 8.9e-05 22.4 0.5 0.00011 22.1 0.4 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal UPF0197 PF05251.7 OAJ31010.1 - 0.00062 20.0 1.1 0.00088 19.5 0.7 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) Fig1 PF12351.3 OAJ31010.1 - 0.0073 16.2 0.6 0.0073 16.2 0.4 1.0 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 ArfGap PF01412.13 OAJ31011.1 - 3.6e-41 139.6 0.2 3.6e-41 139.6 0.1 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf AAA_23 PF13476.1 OAJ31011.1 - 2.1 8.6 10.1 0.88 9.8 5.4 1.4 2 0 0 2 2 2 0 AAA domain DUF3573 PF12097.3 OAJ31011.1 - 2.6 6.5 10.5 4.5 5.7 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF3373 PF11853.3 OAJ31011.1 - 5.7 5.3 11.1 8.9 4.7 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) RrnaAD PF00398.15 OAJ31013.1 - 1.3e-55 188.2 0.0 1.8e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 OAJ31013.1 - 4.3e-10 39.6 0.0 6.9e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ31013.1 - 9.4e-06 25.1 0.0 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 OAJ31013.1 - 5e-05 23.8 0.0 9.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAJ31013.1 - 8.5e-05 21.7 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 OAJ31013.1 - 0.00013 21.5 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 OAJ31013.1 - 0.00023 20.6 0.0 0.00046 19.6 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.14 OAJ31013.1 - 0.00039 20.0 0.0 0.00062 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 OAJ31013.1 - 0.00046 19.8 0.0 0.001 18.6 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 OAJ31013.1 - 0.0015 19.0 0.0 0.0026 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ31013.1 - 0.003 17.3 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ31013.1 - 0.06 12.4 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 OAJ31013.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.1 OAJ31013.1 - 0.081 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 OAJ31013.1 - 0.14 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase CUE PF02845.11 OAJ31014.1 - 1.7e-09 36.9 0.0 3.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain Noc2 PF03715.8 OAJ31016.1 - 7.8e-101 336.8 0.1 1.8e-100 335.7 0.0 1.6 2 0 0 2 2 2 1 Noc2p family BUD22 PF09073.5 OAJ31016.1 - 5.5 5.9 27.9 12 4.8 19.3 1.5 1 0 0 1 1 1 0 BUD22 zf-C2H2_4 PF13894.1 OAJ31018.1 - 9.8e-10 38.0 7.9 0.00024 21.2 2.6 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 OAJ31018.1 - 1.9e-09 37.2 7.6 0.00037 20.6 3.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAJ31018.1 - 2.8e-09 36.8 9.8 1.6e-07 31.2 1.0 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 OAJ31018.1 - 0.00032 20.7 5.5 0.0044 17.1 0.5 2.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 OAJ31018.1 - 0.015 15.6 2.2 0.022 15.1 1.5 1.3 1 0 0 1 1 1 0 TRAF-type zinc finger zf-met PF12874.2 OAJ31018.1 - 0.017 15.3 1.9 0.03 14.5 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Phage_integrase PF00589.17 OAJ31019.1 - 8.7e-05 22.2 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 OAJ31019.1 - 0.11 12.7 0.0 1.2 9.3 0.0 2.2 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain WD40 PF00400.27 OAJ31021.1 - 1.4e-12 46.9 3.9 0.029 14.2 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat F-box-like PF12937.2 OAJ31021.1 - 1.2e-10 40.9 0.0 2.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ31021.1 - 0.00014 21.3 0.0 0.00031 20.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain UIM PF02809.15 OAJ31021.1 - 0.0056 16.1 7.8 0.088 12.4 0.6 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif LRR_4 PF12799.2 OAJ31023.1 - 1.6e-08 33.9 2.7 4.2e-06 26.2 0.8 2.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 OAJ31023.1 - 0.0044 16.9 0.3 9.2 6.9 0.1 3.5 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 OAJ31023.1 - 0.013 15.4 0.3 1.3 9.2 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.1 OAJ31023.1 - 0.03 14.0 0.9 0.51 10.1 0.1 2.4 2 0 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.28 OAJ31023.1 - 0.098 12.7 0.3 26 5.3 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat DUF732 PF05305.9 OAJ31024.1 - 0.083 12.9 0.2 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF732) Arm PF00514.18 OAJ31025.1 - 1.5e-06 27.8 21.6 0.0035 17.1 0.1 9.4 12 0 0 12 12 12 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 OAJ31025.1 - 7.1e-05 23.0 13.5 1.8 8.9 0.0 6.1 6 0 0 6 6 6 3 HEAT repeats HEAT PF02985.17 OAJ31025.1 - 0.00025 20.8 9.6 2 8.6 0.0 6.8 7 0 0 7 7 7 1 HEAT repeat V-ATPase_H_N PF03224.9 OAJ31025.1 - 0.00094 18.3 0.0 3.9 6.4 0.0 3.7 4 0 0 4 4 4 2 V-ATPase subunit H BSP_II PF05432.6 OAJ31025.1 - 0.09 12.0 2.3 0.18 11.0 1.0 1.8 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) ATP-synt_ab PF00006.20 OAJ31026.1 - 4.6e-63 212.5 0.0 1.1e-62 211.4 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 OAJ31026.1 - 4.2e-25 87.7 2.4 1.3e-24 86.1 1.7 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 OAJ31026.1 - 9.6e-23 80.8 0.7 1.6e-22 80.1 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Arch_ATPase PF01637.13 OAJ31026.1 - 0.0021 17.7 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 OAJ31026.1 - 0.0055 16.1 0.1 0.012 15.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 OAJ31026.1 - 0.0099 15.0 0.2 0.017 14.2 0.1 1.4 1 0 0 1 1 1 1 KaiC DUF258 PF03193.11 OAJ31026.1 - 0.018 14.2 0.1 0.032 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 OAJ31026.1 - 0.019 14.6 0.4 0.96 9.1 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 OAJ31026.1 - 0.026 14.5 0.5 0.077 12.9 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 OAJ31026.1 - 0.038 14.1 0.0 0.21 11.7 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ31026.1 - 0.038 14.1 0.0 0.15 12.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 OAJ31026.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 OAJ31026.1 - 0.05 12.4 0.1 0.096 11.5 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.1 OAJ31026.1 - 0.074 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAJ31026.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MAP65_ASE1 PF03999.7 OAJ31027.1 - 1.9e-38 132.4 0.0 3.7e-34 118.3 0.0 2.3 2 0 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) TBPIP PF07106.8 OAJ31027.1 - 0.037 13.5 0.3 0.29 10.6 0.0 2.5 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Asp PF00026.18 OAJ31028.1 - 2.8e-45 154.9 0.7 7.1e-45 153.6 0.5 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 OAJ31028.1 - 3e-05 24.4 0.5 0.014 15.9 0.1 2.6 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 OAJ31028.1 - 7.8e-05 22.6 0.5 0.0012 18.8 0.3 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 OAJ31028.1 - 0.0049 16.4 0.0 0.018 14.6 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Reg_prop PF07494.6 OAJ31028.1 - 0.11 12.5 0.9 33 4.9 0.0 3.7 3 0 0 3 3 3 0 Two component regulator propeller Rep_fac_C PF08542.6 OAJ31029.1 - 2.3e-18 65.9 0.2 6.1e-18 64.5 0.0 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 OAJ31029.1 - 9.5e-13 48.1 0.0 2.1e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 OAJ31029.1 - 9e-05 22.6 0.2 0.00029 21.0 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ31029.1 - 0.00028 21.0 0.2 0.0017 18.5 0.1 2.3 1 1 1 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 OAJ31029.1 - 0.0039 17.2 0.1 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.7 OAJ31029.1 - 0.0044 16.0 0.3 0.3 10.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 OAJ31029.1 - 0.0059 16.4 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 OAJ31029.1 - 0.0078 15.6 0.1 0.038 13.4 0.0 1.9 1 1 0 2 2 2 1 AAA-like domain Rad17 PF03215.10 OAJ31029.1 - 0.015 14.0 0.0 0.059 12.0 0.0 1.9 1 1 1 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 OAJ31029.1 - 0.015 15.2 1.3 0.25 11.3 0.1 2.9 2 2 0 2 2 2 0 AAA ATPase domain SNF2_N PF00176.18 OAJ31029.1 - 0.03 13.1 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF1254 PF06863.7 OAJ31029.1 - 0.092 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) DUF2454 PF10521.4 OAJ31030.1 - 2e-08 33.5 0.0 2.7e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2454) Complex1_LYR PF05347.10 OAJ31031.1 - 1.4e-08 34.4 0.8 2.2e-08 33.7 0.6 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAJ31031.1 - 0.00057 20.0 0.5 0.0011 19.0 0.4 1.5 1 0 0 1 1 1 1 Complex1_LYR-like DEC-1_N PF04625.8 OAJ31031.1 - 0.061 11.9 1.7 0.079 11.6 1.2 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF1180 PF06679.7 OAJ31031.1 - 0.11 12.3 1.7 0.15 11.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PLRV_ORF5 PF01690.12 OAJ31031.1 - 5.2 6.1 11.5 7.9 5.5 7.9 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Neisseria_TspB PF05616.8 OAJ31031.1 - 5.7 5.1 5.8 8 4.6 4.0 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Rubis-subs-bind PF09273.6 OAJ31032.1 - 1.9e-12 47.2 0.0 4.9e-12 45.8 0.0 1.7 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.23 OAJ31032.1 - 3.4e-12 46.9 0.0 7.1e-11 42.6 0.0 2.3 1 1 0 1 1 1 1 SET domain CENP-B_dimeris PF09026.5 OAJ31032.1 - 0.12 12.5 4.3 0.27 11.5 3.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain EAF PF09816.4 OAJ31033.1 - 2.1e-18 66.2 0.0 4.6e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor NOA36 PF06524.7 OAJ31033.1 - 0.0026 17.0 5.7 0.0026 17.0 3.9 2.5 2 1 0 2 2 2 1 NOA36 protein Nop14 PF04147.7 OAJ31033.1 - 5.6 4.7 54.3 1.1 7.1 18.4 2.1 2 0 0 2 2 2 0 Nop14-like family DUF4505 PF14956.1 OAJ31034.1 - 2e-29 102.5 0.0 3.7e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4505) Asp PF00026.18 OAJ31035.1 - 1.5e-45 155.7 0.2 4.9e-45 154.1 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 OAJ31035.1 - 1.5e-05 24.6 0.0 3.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 OAJ31035.1 - 0.0042 17.0 1.2 0.044 13.7 0.8 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal FAM220 PF15487.1 OAJ31036.1 - 0.59 9.4 3.0 0.94 8.7 2.1 1.4 1 0 0 1 1 1 0 FAM220 family CytochromB561_N PF09786.4 OAJ31036.1 - 6.7 5.0 8.7 8.7 4.6 6.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal tRNA-synt_1e PF01406.14 OAJ31037.1 - 1.4e-120 402.0 0.1 1.6e-72 244.1 0.2 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 OAJ31037.1 - 1.6e-08 33.6 1.1 2.1e-05 23.3 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 OAJ31037.1 - 2.7e-05 22.3 0.2 0.0012 16.9 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 OAJ31037.1 - 0.00021 21.4 0.0 0.00021 21.4 0.0 2.8 4 0 0 4 4 4 1 DALR domain tRNA-synt_1c PF00749.16 OAJ31037.1 - 0.0034 16.0 0.5 0.78 8.3 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.13 OAJ31037.1 - 0.013 14.1 0.1 1.1 7.8 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) DUF3991 PF13154.1 OAJ31037.1 - 0.076 13.2 0.6 0.92 9.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3991) Rab5ip PF07019.7 OAJ31038.1 - 1.7e-09 37.6 2.7 2.8e-09 36.9 1.9 1.3 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) RabGAP-TBC PF00566.13 OAJ31039.1 - 5.7e-28 97.8 0.0 1.4e-27 96.5 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain SNARE PF05739.14 OAJ31040.1 - 7.6e-17 60.7 5.5 1.1e-16 60.2 2.9 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 OAJ31040.1 - 4.5e-11 42.8 3.8 7.3e-10 38.9 0.1 2.3 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 OAJ31040.1 - 0.00014 21.5 6.4 0.00031 20.3 1.4 2.2 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3708 PF12501.3 OAJ31040.1 - 0.6 9.9 7.0 8 6.2 0.1 2.4 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter SlyX PF04102.7 OAJ31040.1 - 1.2 9.5 6.6 8.6 6.8 0.5 3.3 2 1 1 3 3 3 0 SlyX Diphthamide_syn PF01866.12 OAJ31041.1 - 3.5e-47 161.1 0.0 1.8e-23 83.2 0.0 4.2 3 1 0 3 3 3 3 Putative diphthamide synthesis protein zf-UBR PF02207.15 OAJ31042.1 - 7.3e-14 51.2 14.7 7.3e-14 51.2 10.2 3.0 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 OAJ31042.1 - 4.8e-09 35.8 0.1 1.6e-08 34.1 0.1 2.0 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.4 OAJ31042.1 - 0.013 14.7 0.3 0.032 13.4 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL WD40 PF00400.27 OAJ31043.1 - 5.7e-10 38.6 0.0 0.37 10.7 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat CPSF100_C PF13299.1 OAJ31043.1 - 0.049 13.8 0.8 0.11 12.7 0.6 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Nucleoporin_N PF08801.6 OAJ31043.1 - 0.095 11.4 0.0 0.39 9.4 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like Nop14 PF04147.7 OAJ31043.1 - 0.16 9.8 15.2 0.23 9.3 10.5 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 OAJ31043.1 - 0.54 9.4 15.3 0.77 8.9 10.6 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 OAJ31043.1 - 8 4.3 10.3 11 3.8 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Rotamase PF00639.16 OAJ31044.1 - 2.6e-19 69.7 0.0 4.9e-19 68.8 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 OAJ31044.1 - 1.3e-16 60.9 0.0 1.7e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 OAJ31044.1 - 4.1e-07 29.7 0.9 4.1e-07 29.7 0.6 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 OAJ31044.1 - 0.024 15.2 0.0 0.056 14.0 0.0 1.6 2 0 0 2 2 2 0 PPIC-type PPIASE domain Yae1_N PF09811.4 OAJ31045.1 - 6.6e-13 47.9 0.4 6.6e-13 47.9 0.2 2.0 2 0 0 2 2 2 1 Essential protein Yae1, N terminal DUF4246 PF14033.1 OAJ31046.1 - 7.3e-119 397.6 0.1 8.8e-119 397.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-Fe_Oxy_2 PF10014.4 OAJ31046.1 - 0.052 12.9 0.0 0.097 12.0 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe dioxygenase PGAP1 PF07819.8 OAJ31047.1 - 5.6e-58 196.1 0.0 8.6e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 OAJ31047.1 - 0.027 13.7 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) RRM_6 PF14259.1 OAJ31048.1 - 0.0002 21.2 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ31048.1 - 0.0023 17.5 0.0 0.0061 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ebola_NP PF05505.7 OAJ31048.1 - 0.28 9.1 11.6 0.59 8.1 8.1 1.6 1 0 0 1 1 1 0 Ebola nucleoprotein Prim_Zn_Ribbon PF08273.7 OAJ31049.1 - 0.068 13.2 0.2 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase RRN7 PF11781.3 OAJ31049.1 - 0.11 11.9 0.2 0.27 10.7 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Peptidase_M43 PF05572.8 OAJ31050.1 - 3.2e-19 69.0 0.7 3.2e-19 69.0 0.5 1.7 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 OAJ31050.1 - 8e-07 29.6 2.6 2e-06 28.3 0.3 2.4 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 OAJ31050.1 - 1.3e-05 24.7 3.6 2.2e-05 24.0 2.5 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 OAJ31050.1 - 3.8e-05 23.8 7.1 7.9e-05 22.7 4.9 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAJ31050.1 - 4.5e-05 23.4 5.9 6.6e-05 22.9 4.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M7 PF02031.11 OAJ31050.1 - 0.0051 16.5 0.6 0.014 15.0 0.3 1.9 1 1 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M10 PF00413.19 OAJ31050.1 - 0.0062 16.2 0.2 0.0079 15.9 0.1 1.4 1 1 0 1 1 1 1 Matrixin GTP_EFTU PF00009.22 OAJ31051.1 - 1.9e-51 174.1 0.0 3.3e-51 173.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 OAJ31051.1 - 7.4e-13 48.1 0.0 1.6e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 OAJ31051.1 - 6.1e-09 35.5 0.0 1.4e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 OAJ31051.1 - 9.9e-05 22.3 0.2 0.001 19.1 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 OAJ31051.1 - 0.0015 18.1 0.0 0.0086 15.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 OAJ31051.1 - 0.0084 16.0 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Sec63 PF02889.11 OAJ31052.1 - 3.1e-78 263.1 0.0 4.8e-78 262.5 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 OAJ31052.1 - 4e-40 137.0 2.5 1.1e-28 99.8 0.0 4.0 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.10 OAJ31052.1 - 3.1e-10 40.1 0.0 3.7e-08 33.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 OAJ31052.1 - 2.8e-06 27.1 0.0 0.0003 20.5 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 OAJ31052.1 - 0.00042 20.4 0.3 0.0069 16.5 0.0 3.1 4 0 0 4 4 4 1 AAA domain T2SE PF00437.15 OAJ31052.1 - 0.0083 15.0 0.2 0.67 8.8 0.0 2.7 3 0 0 3 3 3 1 Type II/IV secretion system protein UvrD-helicase PF00580.16 OAJ31052.1 - 0.094 12.0 0.2 9.7 5.3 0.0 2.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF3759 PF12585.3 OAJ31053.1 - 1.9e-41 139.8 10.1 2.1e-41 139.7 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Borrelia_P83 PF05262.6 OAJ31054.1 - 0.052 11.8 18.6 0.089 11.0 12.9 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein TPR_12 PF13424.1 OAJ31056.1 - 8e-05 22.5 12.5 0.0088 15.9 0.1 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ31056.1 - 0.064 12.9 6.6 1.3 8.7 0.0 3.9 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 OAJ31056.1 - 0.3 11.1 0.0 0.3 11.1 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Zn_clus PF00172.13 OAJ31057.1 - 3.5e-06 26.8 11.3 5.6e-06 26.1 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt5_N PF11942.3 OAJ31057.1 - 0.09 13.4 5.4 3 8.5 0.5 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal ATP-synt_E PF05680.7 OAJ31058.1 - 9.4e-23 79.9 0.1 1e-22 79.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain DUF349 PF03993.7 OAJ31058.1 - 0.037 14.1 0.6 0.046 13.8 0.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) KIP1 PF07765.7 OAJ31058.1 - 0.051 13.4 0.7 0.074 12.8 0.5 1.2 1 0 0 1 1 1 0 KIP1-like protein LdpA_C PF12617.3 OAJ31058.1 - 0.072 12.3 0.1 0.082 12.1 0.0 1.1 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal ABC_trans_N PF14510.1 OAJ31058.1 - 0.089 12.8 0.2 0.12 12.4 0.2 1.5 1 1 0 1 1 1 0 ABC-transporter extracellular N-terminal NAD_Gly3P_dh_C PF07479.9 OAJ31059.1 - 1.3e-49 167.7 0.1 2.2e-49 167.0 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 OAJ31059.1 - 4.1e-48 163.0 0.0 1.8e-47 160.9 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 OAJ31059.1 - 5.1e-06 26.8 0.7 7.7e-05 23.0 0.5 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 OAJ31059.1 - 0.005 16.2 0.4 0.58 9.5 0.2 2.4 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain DUF3375 PF11855.3 OAJ31059.1 - 0.07 11.8 0.0 0.095 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Pox_VLTF3 PF04947.9 OAJ31059.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like Complex1_30kDa PF00329.14 OAJ31060.1 - 7.7e-35 119.2 0.0 1.1e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Bot1p PF12298.3 OAJ31062.1 - 0.061 13.2 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein Perilipin PF03036.11 OAJ31063.1 - 0.00017 20.5 1.2 0.00093 18.1 0.3 2.4 1 1 1 2 2 2 1 Perilipin family MRP-S27 PF10037.4 OAJ31063.1 - 0.038 12.8 0.2 0.057 12.3 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF2408 PF10303.4 OAJ31063.1 - 0.086 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF883 PF05957.8 OAJ31063.1 - 0.086 13.2 0.9 0.7 10.3 0.4 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 OAJ31063.1 - 0.091 12.2 0.7 0.22 11.0 0.5 1.7 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Ring_hydroxyl_A PF00848.14 OAJ31063.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) Pkinase PF00069.20 OAJ31064.1 - 1.8e-35 122.3 0.0 3.8e-35 121.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ31064.1 - 4.7e-21 75.0 0.0 6.5e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_47 PF01532.15 OAJ31065.1 - 1.3e-114 383.3 0.2 1.6e-114 383.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Na_H_Exchanger PF00999.16 OAJ31066.1 - 4.1e-60 203.3 22.5 5.3e-60 202.9 15.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3811 PF11656.3 OAJ31066.1 - 0.045 13.8 0.9 0.13 12.3 0.6 1.7 1 0 0 1 1 1 0 YjbD family (DUF3811) TMCO5 PF14992.1 OAJ31066.1 - 0.048 12.7 1.1 0.076 12.1 0.0 1.8 2 0 0 2 2 2 0 TMCO5 family Pro_isomerase PF00160.16 OAJ31068.1 - 9.8e-42 142.7 0.1 1.3e-41 142.4 0.0 1.2 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SCP2 PF02036.12 OAJ31069.1 - 9.7e-10 38.6 0.0 1.9e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 OAJ31069.1 - 0.0064 16.4 0.0 0.0096 15.8 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Methyltransf_16 PF10294.4 OAJ31070.1 - 1.9e-08 33.9 0.0 1.2e-07 31.3 0.0 1.9 1 1 0 1 1 1 1 Putative methyltransferase Ribosomal_60s PF00428.14 OAJ31070.1 - 0.76 10.2 4.3 1.8 8.9 2.9 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein CRC_subunit PF08624.5 OAJ31071.1 - 4.9e-38 130.1 0.0 8.5e-38 129.3 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit BEX PF04538.7 OAJ31072.1 - 0.014 15.6 0.1 0.016 15.3 0.1 1.2 1 0 0 1 1 1 0 Brain expressed X-linked like family adh_short PF00106.20 OAJ31073.1 - 0.00074 19.4 0.0 0.58 10.0 0.0 2.8 3 0 0 3 3 3 2 short chain dehydrogenase NOA36 PF06524.7 OAJ31073.1 - 1.4 8.0 3.9 2.3 7.3 2.7 1.2 1 0 0 1 1 1 0 NOA36 protein DHC_N1 PF08385.7 OAJ31074.1 - 3.5e-170 567.2 9.1 3.5e-170 567.2 6.3 3.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 OAJ31074.1 - 1.1e-128 429.2 4.8 1.1e-128 429.2 3.3 3.3 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 OAJ31074.1 - 2.5e-83 279.1 0.0 3.6e-82 275.3 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 OAJ31074.1 - 1.5e-27 96.0 0.0 4.2e-13 49.2 0.0 6.0 6 0 0 6 6 6 3 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 OAJ31074.1 - 1.1e-25 90.1 0.0 2e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 OAJ31074.1 - 1.9e-20 73.1 0.0 1.1e-18 67.3 0.0 3.6 5 0 0 5 5 5 1 P-loop containing dynein motor region D3 AAA PF00004.24 OAJ31074.1 - 6.1e-14 52.3 0.0 0.0057 16.8 0.0 5.4 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ31074.1 - 7.3e-14 52.0 0.1 0.02 14.9 0.0 6.0 6 0 0 6 6 4 3 AAA domain AAA_16 PF13191.1 OAJ31074.1 - 3.2e-10 40.2 0.0 0.011 15.7 0.0 5.5 5 0 0 5 5 5 2 AAA ATPase domain AAA_17 PF13207.1 OAJ31074.1 - 2.3e-09 38.1 0.1 0.21 12.4 0.0 5.8 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.1 OAJ31074.1 - 2.3e-09 37.2 0.0 0.19 11.5 0.0 4.9 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.1 OAJ31074.1 - 8.1e-08 31.9 4.2 0.44 10.3 0.0 5.0 5 0 0 5 5 4 2 Part of AAA domain T2SE PF00437.15 OAJ31074.1 - 3.2e-07 29.5 0.0 0.028 13.3 0.0 3.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_18 PF13238.1 OAJ31074.1 - 8.3e-07 29.3 0.1 0.35 11.1 0.0 4.6 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.12 OAJ31074.1 - 8.9e-06 25.2 0.6 0.34 10.3 0.0 4.3 4 0 0 4 4 4 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 OAJ31074.1 - 2e-05 24.6 0.1 1.5 8.8 0.0 5.4 5 1 0 5 5 4 1 Sigma-54 interaction domain AAA_14 PF13173.1 OAJ31074.1 - 3.1e-05 23.8 0.0 0.53 10.1 0.0 4.4 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.16 OAJ31074.1 - 3.8e-05 22.9 3.0 0.45 9.6 0.0 3.8 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 OAJ31074.1 - 4.3e-05 23.1 0.2 11 5.5 0.0 4.7 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.1 OAJ31074.1 - 0.0017 17.8 0.1 12 5.5 0.0 3.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 OAJ31074.1 - 0.0045 16.4 0.0 4.3 6.7 0.0 3.6 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_25 PF13481.1 OAJ31074.1 - 0.0046 16.3 1.5 1.2 8.4 0.0 3.6 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.17 OAJ31074.1 - 0.014 15.5 0.0 15 5.7 0.0 4.3 4 0 0 4 4 4 0 RNA helicase ABC_tran PF00005.22 OAJ31074.1 - 0.023 15.0 3.9 51 4.1 0.0 5.1 5 0 0 5 5 4 0 ABC transporter AAA_11 PF13086.1 OAJ31074.1 - 0.023 14.2 0.0 2.8 7.4 0.0 3.5 3 0 0 3 3 2 0 AAA domain ResIII PF04851.10 OAJ31074.1 - 0.052 13.3 0.0 3 7.6 0.0 3.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.4 OAJ31074.1 - 0.14 11.6 0.2 49 3.4 0.0 3.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF972 PF06156.8 OAJ31074.1 - 0.28 11.5 1.0 39 4.6 0.0 4.6 4 0 0 4 4 3 0 Protein of unknown function (DUF972) SRP54 PF00448.17 OAJ31074.1 - 0.33 10.3 1.3 49 3.2 0.0 3.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain Abhydrolase_5 PF12695.2 OAJ31075.1 - 0.00019 21.2 0.1 0.00078 19.2 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ31075.1 - 0.00022 21.1 0.7 0.0005 20.0 0.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 OAJ31075.1 - 0.00023 20.1 0.0 0.00033 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.15 OAJ31075.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 OAJ31075.1 - 0.042 13.1 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF900 PF05990.7 OAJ31075.1 - 0.13 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.6 OAJ31075.1 - 0.14 11.2 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) zf-rbx1 PF12678.2 OAJ31076.1 - 2.1e-33 114.2 15.5 2.5e-33 114.0 10.7 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 OAJ31076.1 - 1.2e-17 63.5 11.9 1.6e-17 63.1 8.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 OAJ31076.1 - 5.4e-07 29.3 14.4 1.2e-06 28.2 8.5 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAJ31076.1 - 0.00014 21.4 9.5 0.0012 18.4 2.3 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ31076.1 - 0.00027 20.5 10.7 0.003 17.1 7.4 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) VSP PF03302.8 OAJ31076.1 - 0.0062 15.2 2.3 0.0066 15.1 1.6 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein zf-C3HC4_2 PF13923.1 OAJ31076.1 - 0.015 15.2 8.1 0.015 15.2 5.6 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ31076.1 - 0.21 11.3 11.3 1.4 8.7 7.8 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ31076.1 - 0.39 10.4 6.6 11 5.8 4.5 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 OAJ31076.1 - 1.4 8.8 12.7 3.5 7.6 8.8 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 OAJ31076.1 - 2.3 8.4 13.6 36 4.6 9.1 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.3 OAJ31076.1 - 3.3 7.7 16.8 0.22 11.5 6.7 2.3 1 1 2 3 3 3 0 FANCL C-terminal domain FHA PF00498.21 OAJ31077.1 - 1e-14 54.4 0.1 1.8e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 OAJ31077.1 - 6.4e-08 32.3 13.9 9.8e-08 31.7 9.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAJ31077.1 - 0.00031 20.7 7.0 0.00055 20.0 4.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 OAJ31077.1 - 0.019 14.8 5.2 0.032 14.0 3.6 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 OAJ31077.1 - 0.034 13.7 13.0 0.053 13.1 9.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ31077.1 - 0.094 12.4 11.9 0.16 11.6 8.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.24 OAJ31077.1 - 0.73 9.5 7.8 1.3 8.7 5.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.1 OAJ31077.1 - 0.81 9.7 15.3 1.3 9.1 10.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RPAP1_N PF08621.5 OAJ31078.1 - 2.6e-06 26.9 1.6 5.7e-06 25.8 1.1 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal RPAP1_C PF08620.5 OAJ31078.1 - 0.0059 16.4 0.8 0.04 13.7 0.0 2.4 2 0 0 2 2 2 1 RPAP1-like, C-terminal Syntaxin PF00804.20 OAJ31078.1 - 0.48 10.6 4.2 1.1 9.4 1.4 2.5 2 0 0 2 2 2 0 Syntaxin Cation_efflux PF01545.16 OAJ31079.1 - 2.5e-74 249.8 5.9 1.3e-73 247.6 4.1 1.8 1 1 0 1 1 1 1 Cation efflux family DDE_3 PF13358.1 OAJ31082.1 - 2.2e-29 102.0 0.0 3.3e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAJ31082.1 - 1.1e-06 29.3 0.5 3.4e-06 27.7 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.1 OAJ31082.1 - 3.3e-05 23.3 0.3 0.012 15.1 0.0 3.0 3 0 0 3 3 3 1 Winged helix-turn helix DDE_1 PF03184.14 OAJ31082.1 - 0.00053 19.1 0.0 0.00086 18.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 OAJ31082.1 - 0.0011 19.0 0.0 0.0031 17.6 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain HTH_29 PF13551.1 OAJ31082.1 - 0.08 13.0 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Ham1p_like PF01725.11 OAJ31083.1 - 7e-54 182.0 0.0 7.9e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Histone PF00125.19 OAJ31084.1 - 1.4e-22 79.5 0.4 1.9e-22 79.1 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAJ31084.1 - 4.5e-07 29.8 0.1 8.5e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 OAJ31084.1 - 0.00037 20.7 0.0 0.00058 20.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 OAJ31084.1 - 0.034 14.6 0.3 0.045 14.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.8 OAJ31084.1 - 0.042 13.2 0.1 0.074 12.5 0.1 1.4 1 1 0 1 1 1 0 Replication protein C N-terminal domain Ada3 PF10198.4 OAJ31085.1 - 1.1e-26 93.1 2.2 2.5e-26 91.9 0.0 2.4 2 1 0 2 2 2 1 Histone acetyltransferases subunit 3 Histone PF00125.19 OAJ31087.1 - 1.3e-25 89.2 0.0 1.8e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAJ31087.1 - 1.2e-05 25.3 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Lactamase_B_2 PF12706.2 OAJ31088.1 - 1.4e-20 73.7 0.0 4.2e-20 72.1 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 OAJ31088.1 - 5e-10 38.7 0.0 1.2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 OAJ31088.1 - 5.3e-06 26.2 0.1 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PIF1 PF05970.9 OAJ31089.1 - 1.5e-103 346.5 0.0 2.1e-103 346.1 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ31089.1 - 2.7e-62 209.7 0.1 1.4e-61 207.4 0.1 2.3 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Herpes_Helicase PF02689.9 OAJ31089.1 - 2.7e-08 32.0 0.1 7.8e-08 30.5 0.0 1.6 2 0 0 2 2 2 1 Helicase AAA_30 PF13604.1 OAJ31089.1 - 9.3e-07 28.6 0.1 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 OAJ31089.1 - 0.0047 17.0 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 OAJ31089.1 - 0.0068 16.1 0.2 0.026 14.2 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 OAJ31089.1 - 0.019 13.8 0.0 0.056 12.3 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.11 OAJ31089.1 - 0.2 10.8 0.0 13 4.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DDE_Tnp_4 PF13359.1 OAJ31091.1 - 6.1e-23 81.1 0.0 1.1e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4356 PF14266.1 OAJ31091.1 - 0.0061 15.0 0.1 0.0091 14.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4356) Head-tail_con PF12236.3 OAJ31091.1 - 0.029 12.7 0.9 0.045 12.1 0.6 1.2 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein Trypan_glycop PF00913.14 OAJ31091.1 - 0.33 9.8 4.0 0.49 9.2 2.8 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) Myb_DNA-bind_4 PF13837.1 OAJ31092.1 - 9.1e-05 22.5 1.5 0.0001 22.3 0.1 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF2884 PF11101.3 OAJ31093.1 - 0.022 14.1 0.2 0.48 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) BRCT PF00533.21 OAJ31093.1 - 0.046 13.8 0.0 13 6.0 0.0 2.7 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain She9_MDM33 PF05546.6 OAJ31093.1 - 0.1 12.1 0.6 0.28 10.6 0.2 1.7 2 0 0 2 2 2 0 She9 / Mdm33 family Mating_N PF12731.2 OAJ31093.1 - 0.19 11.6 2.5 2 8.3 0.0 2.6 2 0 0 2 2 2 0 Mating-type protein beta 1 CRAL_TRIO PF00650.15 OAJ31094.1 - 3.1e-29 101.5 0.0 4.7e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 OAJ31094.1 - 1.2e-10 41.5 0.0 2.6e-10 40.3 0.0 1.5 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ31094.1 - 8.5e-07 29.0 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain LSM PF01423.17 OAJ31095.1 - 2e-15 56.0 0.0 3e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain DUF3510 PF12022.3 OAJ31095.1 - 0.0015 18.5 0.0 0.0019 18.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) GRP PF07172.6 OAJ31095.1 - 2.2 8.8 28.4 3.1 8.3 19.7 1.2 1 0 0 1 1 1 0 Glycine rich protein family MFS_1 PF07690.11 OAJ31096.1 - 1.3e-16 60.3 42.7 1.3e-16 60.3 29.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 OAJ31096.1 - 0.024 14.4 1.5 0.097 12.4 1.0 2.1 1 0 0 1 1 1 0 MFS_1 like family Glyco_transf_8 PF01501.15 OAJ31097.1 - 1.3e-28 99.9 0.0 2.9e-25 89.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 OAJ31097.1 - 0.0049 16.2 0.0 0.0081 15.5 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Thiol_cytolysin PF01289.14 OAJ31097.1 - 0.012 13.9 0.0 0.019 13.3 0.0 1.2 1 0 0 1 1 1 0 Thiol-activated cytolysin PITH PF06201.8 OAJ31098.1 - 2.4e-34 118.3 0.0 3.1e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 PITH domain ATP-synt PF00231.14 OAJ31099.1 - 3.4e-69 233.4 3.2 4e-69 233.1 2.2 1.1 1 0 0 1 1 1 1 ATP synthase Bac_rhamnosid_N PF08531.5 OAJ31099.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain eIF-5_eIF-2B PF01873.12 OAJ31100.1 - 8.1e-45 151.5 0.6 1.3e-44 150.8 0.4 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 OAJ31100.1 - 0.0012 18.1 0.1 0.002 17.4 0.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding MSP1_C PF07462.6 OAJ31100.1 - 0.56 8.5 4.6 1.6 7.0 3.3 1.6 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Pyridox_oxidase PF01243.15 OAJ31101.1 - 1.5e-11 44.1 0.0 6.4e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DUF374 PF04028.8 OAJ31101.1 - 0.043 13.0 0.1 0.1 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Nodulin_late PF07127.6 OAJ31102.1 - 0.17 12.0 2.5 1.8 8.7 0.1 2.6 3 0 0 3 3 3 0 Late nodulin protein HeLo PF14479.1 OAJ31103.1 - 0.0011 18.7 1.8 0.0013 18.5 0.0 1.8 2 0 0 2 2 2 1 Prion-inhibition and propagation DUF3338 PF11819.3 OAJ31103.1 - 5.2 6.5 8.6 0.94 8.9 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3338) Ribosomal_L21e PF01157.13 OAJ31104.1 - 2e-36 123.7 1.4 2e-36 123.7 1.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e TRAM PF01938.15 OAJ31104.1 - 0.03 14.1 0.5 9.1 6.1 0.0 2.3 2 0 0 2 2 2 0 TRAM domain TRAP-gamma PF07074.7 OAJ31104.1 - 0.051 13.0 0.2 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF3708 PF12501.3 OAJ31104.1 - 0.063 13.1 0.0 0.074 12.8 0.0 1.1 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Sigma_reg_N PF13800.1 OAJ31105.1 - 0.83 9.7 3.0 3.8 7.6 0.0 2.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF1072 PF06380.6 OAJ31105.1 - 1.1 8.9 5.8 2.1 8.0 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) RasGEF PF00617.14 OAJ31106.1 - 4.1e-42 144.0 0.0 7.4e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 OAJ31106.1 - 3.5e-10 39.9 0.5 3.5e-10 39.9 0.3 1.8 2 0 0 2 2 2 1 RasGEF N-terminal motif Ribosomal_S4 PF00163.14 OAJ31107.1 - 2.8e-27 94.9 0.9 5.9e-27 93.8 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 OAJ31107.1 - 5e-12 45.0 1.5 5e-12 45.0 1.0 2.8 3 0 0 3 3 3 1 S4 domain AAA_13 PF13166.1 OAJ31109.1 - 0.21 10.0 2.5 0.35 9.2 1.7 1.2 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 OAJ31110.1 - 2.3e-18 65.9 0.4 5.1e-18 64.8 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ31110.1 - 1.7e-07 30.9 9.9 2.7e-07 30.3 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3074 PF11274.3 OAJ31111.1 - 1.2e-44 152.1 0.0 1.6e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) ORC4_C PF14629.1 OAJ31112.1 - 1.2e-24 86.9 0.0 3.4e-24 85.3 0.0 1.8 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 OAJ31112.1 - 1.7e-11 44.4 1.4 1.5e-10 41.3 0.5 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 OAJ31112.1 - 0.0062 15.4 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) CDC45 PF02724.9 OAJ31112.1 - 0.54 8.2 15.0 0.11 10.4 4.5 2.1 2 0 0 2 2 2 0 CDC45-like protein AAA_18 PF13238.1 OAJ31112.1 - 1.3 9.2 5.0 1 9.6 0.8 2.7 2 1 0 2 2 2 0 AAA domain Thioredoxin PF00085.15 OAJ31113.1 - 0.00011 21.7 0.1 0.00018 21.1 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.11 OAJ31113.1 - 0.06 12.8 0.2 0.092 12.2 0.1 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 DUF3417 PF11897.3 OAJ31113.1 - 0.066 13.1 0.5 0.12 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) HOOK PF05622.7 OAJ31114.1 - 1.3e-48 165.4 41.7 1.3e-48 165.4 28.9 3.5 2 1 1 3 3 3 1 HOOK protein Filament PF00038.16 OAJ31114.1 - 0.01 15.3 86.8 0.066 12.6 10.3 5.0 1 1 1 3 3 3 0 Intermediate filament protein Reo_sigmaC PF04582.7 OAJ31114.1 - 0.039 13.1 23.3 0.058 12.5 3.8 3.8 3 1 2 5 5 5 0 Reovirus sigma C capsid protein Ribosomal_L7Ae PF01248.21 OAJ31116.1 - 3.6e-26 90.5 0.1 4.3e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 OAJ31116.1 - 0.0033 17.2 0.0 0.0037 17.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 OAJ31116.1 - 0.019 14.7 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Herpes_U34 PF04541.8 OAJ31116.1 - 0.058 12.2 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus virion protein U34 Paf67 PF10255.4 OAJ31117.1 - 1.6e-157 524.5 0.0 2.4e-157 524.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 OAJ31117.1 - 0.0045 16.8 0.0 0.0045 16.8 0.0 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ31117.1 - 0.0069 15.9 0.0 0.054 13.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat DEAD PF00270.24 OAJ31119.1 - 6.7e-32 110.2 0.0 2.1e-31 108.6 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ31119.1 - 2.8e-22 78.3 0.0 7.8e-22 76.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NAD_binding_3 PF03447.11 OAJ31119.1 - 0.015 15.7 0.6 25 5.3 0.0 3.8 3 0 0 3 3 3 0 Homoserine dehydrogenase, NAD binding domain DUF1253 PF06862.7 OAJ31119.1 - 0.079 11.3 0.0 5.5 5.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) PLDc PF00614.17 OAJ31120.1 - 3e-16 58.6 0.3 3.4e-07 29.8 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 OAJ31120.1 - 5.9e-11 42.2 0.0 1e-06 28.5 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 OAJ31120.1 - 9.7e-09 35.0 0.0 2.7e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 PX domain PH PF00169.24 OAJ31120.1 - 0.0053 16.9 0.0 0.023 14.8 0.0 2.0 1 1 0 1 1 1 1 PH domain Lactamase_B_2 PF12706.2 OAJ31121.1 - 6e-09 35.7 0.3 1.8e-08 34.1 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain PXA PF02194.10 OAJ31123.1 - 1.4e-13 50.8 0.0 3.4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 OAJ31123.1 - 5.3e-07 29.7 0.0 1.2e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Sorting nexin C terminal DUF2273 PF10031.4 OAJ31123.1 - 0.11 12.1 1.8 0.19 11.3 1.3 1.3 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) UCH PF00443.24 OAJ31124.1 - 1.7e-49 168.3 0.0 1.3e-48 165.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ31124.1 - 3.2e-19 69.4 0.4 2.4e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 OAJ31124.1 - 1.1e-08 35.0 1.0 1.1e-08 35.0 0.7 3.2 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein PBP1_TM PF14812.1 OAJ31124.1 - 0.84 9.9 17.4 0.21 11.9 5.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 OAJ31124.1 - 1.8 8.0 13.0 3.2 7.2 6.0 2.3 2 0 0 2 2 2 0 Nucleoplasmin RabGAP-TBC PF00566.13 OAJ31125.1 - 7.4e-43 146.5 0.2 9.9e-43 146.0 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CENP-F_leu_zip PF10473.4 OAJ31126.1 - 0.0014 18.4 0.7 0.002 17.9 0.5 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3166 PF11365.3 OAJ31126.1 - 0.0054 17.1 0.4 0.014 15.8 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3166) APG6 PF04111.7 OAJ31126.1 - 0.032 13.2 2.3 0.041 12.9 1.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Herpes_UL6 PF01763.11 OAJ31126.1 - 0.041 12.0 0.2 0.042 12.0 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like RDM PF11002.3 OAJ31126.1 - 0.05 13.2 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 RFPL defining motif (RDM) DivIC PF04977.10 OAJ31126.1 - 0.071 12.6 4.7 0.15 11.5 3.2 1.5 1 1 0 1 1 1 0 Septum formation initiator Blo-t-5 PF11642.3 OAJ31126.1 - 0.12 12.0 3.1 0.17 11.6 2.2 1.2 1 0 0 1 1 1 0 Mite allergen Blo t 5 HMG_box PF00505.14 OAJ31127.1 - 1.6e-11 44.2 0.3 2.9e-11 43.4 0.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ31127.1 - 1.4e-10 41.4 0.2 2.7e-10 40.4 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain DSPc PF00782.15 OAJ31128.1 - 5.3e-16 58.4 0.0 2.4e-14 53.0 0.2 2.6 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAJ31128.1 - 0.014 14.7 0.1 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase GOLD_2 PF13897.1 OAJ31128.1 - 1.1 9.4 1.8 2.3 8.4 0.5 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking WD40 PF00400.27 OAJ31129.1 - 8.3e-12 44.5 1.5 0.00071 19.3 0.2 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat 5_nucleotid_C PF02872.13 OAJ31129.1 - 0.014 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain TPR_12 PF13424.1 OAJ31130.1 - 3.2e-05 23.7 0.0 0.00067 19.5 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc5 PF12862.2 OAJ31130.1 - 0.085 12.7 0.3 0.35 10.7 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 SNARE_assoc PF09335.6 OAJ31132.1 - 6.6e-15 55.4 1.3 1.5e-14 54.2 0.9 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein PUF PF00806.14 OAJ31133.1 - 1.1e-14 52.9 0.9 2.4e-07 29.8 0.0 4.8 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat Abhydrolase_5 PF12695.2 OAJ31134.1 - 8.5e-05 22.3 0.0 0.00021 21.0 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 OAJ31134.1 - 0.00015 21.1 0.0 0.00029 20.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 OAJ31134.1 - 0.0014 18.5 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAJ31134.1 - 0.0087 15.6 0.0 0.029 13.9 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein CAP_GLY PF01302.20 OAJ31136.1 - 1.3e-19 69.6 0.1 2.6e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 OAJ31136.1 - 8.3e-09 34.8 7.6 5e-05 22.8 0.7 5.4 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ31136.1 - 7.8e-06 25.5 1.5 0.058 13.1 0.1 4.1 3 1 2 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 OAJ31136.1 - 0.82 9.9 2.6 22 5.4 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.28 OAJ31136.1 - 3 8.2 11.7 65 4.1 0.1 5.2 4 2 1 5 5 5 0 Leucine Rich Repeat FRG1 PF06229.7 OAJ31137.1 - 4.9e-21 75.0 3.3 1e-08 34.8 0.0 3.4 3 0 0 3 3 3 3 FRG1-like family Fascin PF06268.8 OAJ31137.1 - 1.1e-06 28.7 0.0 0.00085 19.3 0.0 2.4 2 0 0 2 2 2 2 Fascin domain DUF4444 PF14563.1 OAJ31137.1 - 0.043 13.2 0.1 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4444) DNase_NucA_NucB PF14040.1 OAJ31138.1 - 4.4e-26 91.2 1.5 6.3e-26 90.7 1.0 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Me-amine-dh_L PF02975.9 OAJ31138.1 - 1.8 8.5 8.8 0.28 11.1 3.3 1.7 1 1 0 1 1 1 0 Methylamine dehydrogenase, L chain DUF4149 PF13664.1 OAJ31140.1 - 4.6e-19 68.3 3.4 4.6e-19 68.3 2.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF2945 PF11160.3 OAJ31141.1 - 1.8e-11 43.6 1.9 7e-11 41.7 0.0 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2945) MIP-T3 PF10243.4 OAJ31141.1 - 0.013 13.9 65.2 0.017 13.6 45.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 OAJ31141.1 - 7.6 4.6 36.9 9.3 4.3 25.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Rox3 PF08633.5 OAJ31142.1 - 3.1 8.0 19.2 0.75 10.0 4.2 2.9 2 1 0 3 3 3 0 Rox3 mediator complex subunit FGGY_N PF00370.16 OAJ31143.1 - 2.1e-72 243.3 0.1 3e-72 242.8 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 OAJ31143.1 - 1e-67 227.5 3.1 2.5e-67 226.3 1.2 2.1 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF1212 PF06738.7 OAJ31144.1 - 2.8e-39 134.5 1.0 2.8e-39 134.5 0.7 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 OAJ31144.1 - 3.8e-17 62.4 8.3 3.8e-17 62.4 5.7 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3815) ABC_tran PF00005.22 OAJ31145.1 - 3.4e-46 156.9 0.0 3.1e-26 92.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 OAJ31145.1 - 4.1e-37 128.0 19.3 3.5e-16 59.4 8.7 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_23 PF13476.1 OAJ31145.1 - 3.6e-11 43.7 1.3 4.3e-06 27.1 0.4 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 OAJ31145.1 - 2.8e-10 40.6 0.4 0.0012 18.8 0.0 4.2 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 OAJ31145.1 - 5.6e-09 35.5 6.7 0.0028 16.9 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 OAJ31145.1 - 3e-08 33.0 1.0 0.0047 16.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 OAJ31145.1 - 1.4e-06 27.6 0.1 0.02 14.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 OAJ31145.1 - 1.6e-06 28.6 0.9 0.03 14.8 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein T2SE PF00437.15 OAJ31145.1 - 5.8e-06 25.3 0.1 0.02 13.8 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 OAJ31145.1 - 1.9e-05 24.7 0.6 0.25 11.3 0.1 3.3 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 OAJ31145.1 - 5.7e-05 23.0 1.2 0.031 14.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.1 OAJ31145.1 - 6.8e-05 22.0 0.1 0.033 13.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.18 OAJ31145.1 - 9e-05 22.3 3.2 0.15 11.8 0.3 2.6 2 0 0 2 2 2 2 Dynamin family AAA_25 PF13481.1 OAJ31145.1 - 0.00015 21.2 0.0 0.29 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Adeno_IVa2 PF02456.10 OAJ31145.1 - 0.00019 20.2 0.0 0.071 11.7 0.0 2.2 2 0 0 2 2 2 2 Adenovirus IVa2 protein FtsK_SpoIIIE PF01580.13 OAJ31145.1 - 0.00046 19.7 0.3 0.28 10.6 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 OAJ31145.1 - 0.00047 20.0 1.4 0.0063 16.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_30 PF13604.1 OAJ31145.1 - 0.00076 19.1 2.4 0.54 9.8 0.3 3.4 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 OAJ31145.1 - 0.00077 18.6 0.1 0.15 11.1 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 OAJ31145.1 - 0.0018 17.8 1.0 0.45 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain MobB PF03205.9 OAJ31145.1 - 0.0019 17.8 1.1 0.2 11.3 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 OAJ31145.1 - 0.0034 17.5 1.4 3.7 7.7 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_17 PF13207.1 OAJ31145.1 - 0.0055 17.5 1.9 0.65 10.8 0.1 3.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAJ31145.1 - 0.01 15.7 4.7 1.9 8.3 0.0 3.4 4 0 0 4 4 3 2 AAA domain GTP_EFTU PF00009.22 OAJ31145.1 - 0.031 13.7 0.0 5.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_ATPase PF09818.4 OAJ31145.1 - 0.036 12.6 5.2 2 6.8 0.0 3.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class NACHT PF05729.7 OAJ31145.1 - 0.05 13.2 1.9 8.1 6.0 0.2 2.6 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.4 OAJ31145.1 - 0.075 11.6 0.2 2.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.24 OAJ31145.1 - 0.095 12.9 0.3 33 4.6 0.1 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 OAJ31145.1 - 0.097 11.6 0.0 13 4.7 0.0 2.2 2 0 0 2 2 2 0 Septin Viral_helicase1 PF01443.13 OAJ31145.1 - 0.2 11.1 0.2 23 4.4 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 OAJ31145.1 - 0.21 11.0 4.2 4 6.8 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 OAJ31145.1 - 0.22 11.4 0.0 30 4.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 OAJ31145.1 - 0.28 11.3 0.5 27 5.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 OAJ31145.1 - 0.79 10.0 5.2 2 8.7 0.3 3.2 3 0 0 3 3 3 0 AAA domain Maf PF02545.9 OAJ31146.1 - 1.1e-44 151.9 0.0 1.3e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DUF2236 PF09995.4 OAJ31147.1 - 1.4e-20 73.6 1.5 3.5e-19 69.0 1.0 2.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Metallophos PF00149.23 OAJ31148.1 - 2e-07 30.6 0.2 4.1e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Lipase_GDSL_3 PF14606.1 OAJ31148.1 - 0.065 12.9 0.0 7 6.3 0.0 2.3 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Pex14_N PF04695.8 OAJ31149.1 - 4.1 7.4 7.9 6.5 6.8 5.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GATA PF00320.22 OAJ31150.1 - 0.0023 17.2 10.2 0.004 16.4 2.4 3.4 3 0 0 3 3 3 2 GATA zinc finger Pro_CA PF00484.14 OAJ31151.1 - 2.4e-37 128.3 0.0 3.2e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_1 PF00561.15 OAJ31151.1 - 0.034 13.7 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2922 PF11148.3 OAJ31151.1 - 0.068 12.8 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) UDPGT PF00201.13 OAJ31152.1 - 2.1e-13 49.6 0.1 3.3e-13 49.0 0.1 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 OAJ31152.1 - 0.11 11.7 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 ADH_zinc_N PF00107.21 OAJ31154.1 - 7.9e-11 41.6 0.0 1.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ31154.1 - 0.0018 18.0 0.0 0.032 13.9 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ArfGap PF01412.13 OAJ31155.1 - 1.2e-32 112.1 0.5 3e-32 110.8 0.0 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf AIG2 PF06094.7 OAJ31156.1 - 8.5e-12 45.4 0.0 1.4e-11 44.8 0.0 1.4 1 1 0 1 1 1 1 AIG2-like family p450 PF00067.17 OAJ31157.1 - 1.7e-71 241.1 0.0 5.8e-44 150.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 ABC_trans_N PF14510.1 OAJ31157.1 - 0.11 12.5 0.1 0.47 10.5 0.0 2.1 3 0 0 3 3 3 0 ABC-transporter extracellular N-terminal Pkinase PF00069.20 OAJ31158.1 - 1.4e-40 139.0 0.4 2.7e-23 82.4 0.3 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ31158.1 - 1.1e-11 44.2 0.6 5.7e-09 35.4 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 OAJ31158.1 - 0.24 10.1 0.0 0.34 9.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CorA PF01544.13 OAJ31159.1 - 4.8e-20 71.7 3.1 5e-11 42.1 0.1 3.2 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF3605 PF12239.3 OAJ31160.1 - 1.2e-22 80.4 0.4 4.4e-18 65.6 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) DUF605 PF04652.11 OAJ31160.1 - 0.32 10.3 13.2 0.43 9.9 9.2 1.2 1 0 0 1 1 1 0 Vta1 like CAF-1_p150 PF11600.3 OAJ31160.1 - 3.6 6.9 11.1 5.4 6.3 7.7 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AF-4 PF05110.8 OAJ31160.1 - 6.5 4.4 17.9 8.8 4.0 12.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein THRAP3_BCLAF1 PF15440.1 OAJ31160.1 - 7.6 5.0 12.0 10 4.6 8.3 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Dynamin_M PF01031.15 OAJ31161.1 - 3.7e-15 55.4 0.0 3.8e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Dynamin central region Dynamin_M PF01031.15 OAJ31162.1 - 1.6e-11 43.5 0.0 1.8e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 OAJ31163.1 - 7.7e-23 81.1 0.0 1e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 OAJ31163.1 - 3.8e-21 75.1 0.0 5.2e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region CAP18_C PF12153.3 OAJ31164.1 - 0.0013 18.3 0.3 0.023 14.3 0.0 2.4 2 0 0 2 2 2 1 LPS binding domain of CAP18 (C terminal) AphA_like PF14557.1 OAJ31164.1 - 0.03 13.8 0.6 0.044 13.3 0.4 1.2 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator Aminotran_5 PF00266.14 OAJ31165.1 - 1.9e-20 72.9 0.0 1.2e-19 70.3 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 OAJ31165.1 - 0.0015 17.5 0.0 0.0024 16.8 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II SMN PF06003.7 OAJ31165.1 - 0.025 13.6 9.3 0.17 10.9 3.3 2.2 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Nop14 PF04147.7 OAJ31165.1 - 1 7.2 11.9 1.4 6.7 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.6 OAJ31165.1 - 2.3 7.9 7.8 4.7 7.0 5.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CobT PF06213.7 OAJ31165.1 - 7.3 5.6 13.6 15 4.6 9.4 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2456 PF10445.4 OAJ31166.1 - 3.7e-22 78.0 2.1 3.7e-22 78.0 1.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) GTP_EFTU PF00009.22 OAJ31168.1 - 1.4e-60 203.9 0.3 2.4e-60 203.2 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 OAJ31168.1 - 3.4e-36 123.4 0.0 7.8e-36 122.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 OAJ31168.1 - 3.1e-21 75.0 0.0 7.7e-21 73.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 OAJ31168.1 - 1.8e-13 50.1 0.0 5.3e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 OAJ31168.1 - 1.2e-11 44.5 0.0 3.6e-11 43.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAJ31168.1 - 0.00011 22.1 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase UCR_14kD PF02271.11 OAJ31170.1 - 5.6e-37 125.7 0.5 6.4e-37 125.5 0.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit NAD_binding_8 PF13450.1 OAJ31171.1 - 2.4e-07 30.6 0.0 1.5e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 OAJ31171.1 - 6.8e-07 28.7 0.1 3.8e-05 22.9 0.0 2.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 OAJ31171.1 - 3.2e-05 23.0 0.1 7.1e-05 21.8 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 OAJ31171.1 - 0.0031 16.2 0.0 0.0066 15.1 0.0 1.5 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.1 OAJ31171.1 - 0.015 15.0 0.1 0.07 12.9 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 OAJ31171.1 - 0.02 13.9 0.0 0.26 10.3 0.0 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase OCD_Mu_crystall PF02423.10 OAJ31171.1 - 0.05 12.3 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Thi4 PF01946.12 OAJ31171.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 OAJ31171.1 - 0.17 12.3 0.1 2.8 8.4 0.2 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cpn60_TCP1 PF00118.19 OAJ31173.1 - 1.3e-152 508.8 0.1 2.4e-152 507.9 0.0 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1572 PF07609.6 OAJ31173.1 - 0.072 12.6 0.0 0.94 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1572) CLASP_N PF12348.3 OAJ31174.1 - 2e-17 63.3 0.0 9.7e-05 21.8 0.0 5.1 5 0 0 5 5 5 4 CLASP N terminal HEAT_2 PF13646.1 OAJ31174.1 - 2.2e-13 50.2 7.1 0.022 15.0 0.0 8.1 6 3 2 8 8 8 4 HEAT repeats HEAT PF02985.17 OAJ31174.1 - 5.4e-13 47.8 14.6 0.0017 18.2 0.1 9.2 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.1 OAJ31174.1 - 0.00017 21.9 12.0 0.6 10.6 0.0 6.8 6 1 1 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 OAJ31174.1 - 0.00028 21.1 0.0 18 5.7 0.0 5.5 4 2 2 6 6 6 0 Vacuolar 14 Fab1-binding region Proteasom_PSMB PF10508.4 OAJ31174.1 - 0.0027 16.0 0.0 1.6 6.8 0.0 2.9 3 0 0 3 3 3 2 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 OAJ31174.1 - 0.0037 17.1 0.4 0.91 9.3 0.0 4.2 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 OAJ31174.1 - 0.02 14.7 0.2 5.5 6.9 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) Arm PF00514.18 OAJ31174.1 - 0.035 13.9 4.4 1.4 8.8 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 OAJ31174.1 - 0.05 13.5 2.0 6.4 6.8 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion LNS2 PF08235.8 OAJ31176.1 - 7.8e-67 223.7 0.0 6.4e-54 181.7 0.0 2.4 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 OAJ31176.1 - 5.3e-29 100.1 0.0 2.7e-19 68.8 0.0 2.4 2 0 0 2 2 2 2 lipin, N-terminal conserved region AF1Q PF15017.1 OAJ31176.1 - 0.0018 18.1 0.1 0.0075 16.1 0.0 2.0 1 0 0 1 1 1 1 Drug resistance and apoptosis regulator Acid_phosphat_B PF03767.9 OAJ31176.1 - 0.0081 15.5 0.0 0.04 13.2 0.0 2.0 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Bd3614-deam PF14439.1 OAJ31176.1 - 0.041 13.7 0.1 0.097 12.5 0.1 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase Transferase PF02458.10 OAJ31177.1 - 8.1e-09 34.4 0.0 3.5e-06 25.7 0.0 3.0 3 0 0 3 3 3 3 Transferase family DUF1620 PF07774.8 OAJ31178.1 - 2.6e-58 196.8 0.0 4.3e-58 196.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 OAJ31178.1 - 3.3e-11 43.1 7.6 5.3e-05 22.7 0.0 4.0 4 0 0 4 4 4 2 PQQ-like domain PQQ PF01011.16 OAJ31178.1 - 2.7e-09 36.1 0.2 0.0029 17.0 0.0 4.3 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_3 PF13570.1 OAJ31178.1 - 0.24 11.7 4.4 15 5.9 0.0 5.5 6 0 0 6 6 6 0 PQQ-like domain adh_short_C2 PF13561.1 OAJ31179.1 - 3.3e-33 115.4 0.1 4.1e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ31179.1 - 5.9e-29 101.1 0.3 7.8e-29 100.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ31179.1 - 2.1e-11 43.8 0.1 4.2e-11 42.8 0.1 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 OAJ31179.1 - 0.00013 21.5 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 OAJ31179.1 - 0.0093 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 OAJ31179.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) B-block_TFIIIC PF04182.7 OAJ31180.1 - 7e-07 29.0 0.0 2.1e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC PNGaseA PF12222.3 OAJ31181.1 - 6.5e-60 203.1 0.3 1.9e-40 139.0 0.1 2.2 2 0 0 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A SH3_9 PF14604.1 OAJ31183.1 - 1.5e-08 34.0 0.0 2.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ31183.1 - 6.9e-08 31.7 0.0 1.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ31183.1 - 0.00052 19.4 0.1 0.0014 18.0 0.0 1.7 1 1 0 1 1 1 1 Variant SH3 domain NmrA PF05368.8 OAJ31185.1 - 5.7e-25 87.9 0.0 7.4e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAJ31185.1 - 4.8e-12 46.2 0.0 3.6e-11 43.4 0.0 2.0 1 1 1 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 OAJ31185.1 - 7.4e-07 28.4 0.0 1.4e-06 27.5 0.0 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase TrkA_N PF02254.13 OAJ31185.1 - 0.0018 18.2 0.0 0.0067 16.4 0.0 2.0 3 0 0 3 3 3 1 TrkA-N domain Shikimate_DH PF01488.15 OAJ31185.1 - 0.0077 16.3 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 OAJ31185.1 - 0.026 14.3 0.1 0.06 13.1 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 OAJ31185.1 - 0.2 12.0 1.3 0.38 11.2 0.0 2.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent OPA3 PF07047.7 OAJ31186.1 - 6.9e-12 45.2 0.1 7.8e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Pyr_redox_dim PF02852.17 OAJ31187.1 - 1e-40 138.1 0.1 2.5e-40 136.9 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 OAJ31187.1 - 1.7e-38 132.5 19.9 5.4e-28 98.2 5.4 3.8 2 1 2 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ31187.1 - 5.4e-22 78.0 11.2 3.5e-19 68.9 1.6 3.8 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAJ31187.1 - 5.7e-12 46.1 0.6 2.8e-07 30.8 0.1 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAJ31187.1 - 7.5e-12 45.0 0.2 7.5e-12 45.0 0.1 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ31187.1 - 1.8e-09 37.4 4.8 5.8e-05 23.0 0.3 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 OAJ31187.1 - 1.3e-07 30.8 15.1 2.2e-07 30.0 3.8 3.0 2 2 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 OAJ31187.1 - 1.5e-07 30.6 2.5 1.5e-07 30.6 1.7 3.6 3 1 0 4 4 4 1 FAD binding domain K_oxygenase PF13434.1 OAJ31187.1 - 5.2e-07 28.8 0.9 0.032 13.1 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 OAJ31187.1 - 8e-07 28.3 5.0 6.8e-06 25.3 0.1 2.5 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 OAJ31187.1 - 2.7e-06 26.1 14.2 0.00014 20.5 0.8 4.0 3 1 1 4 4 4 2 HI0933-like protein DAO PF01266.19 OAJ31187.1 - 6.4e-05 22.0 18.2 0.0027 16.6 0.4 3.7 3 1 1 4 4 4 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 OAJ31187.1 - 0.00017 21.1 4.0 0.0019 17.7 0.3 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 OAJ31187.1 - 0.00055 19.0 12.4 0.014 14.4 0.8 3.5 3 1 0 3 3 3 2 FAD binding domain THF_DHG_CYH_C PF02882.14 OAJ31187.1 - 0.024 13.7 0.4 0.082 11.9 0.1 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.7 OAJ31187.1 - 0.11 11.4 2.6 0.16 10.8 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 OAJ31187.1 - 7.3 6.9 6.9 24 5.2 0.8 3.0 3 1 0 3 3 3 0 Putative NAD(P)-binding IGPS PF00218.16 OAJ31188.1 - 2.4e-85 285.6 0.0 1.3e-84 283.2 0.0 2.2 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 OAJ31188.1 - 5.3e-45 153.2 0.0 1e-44 152.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.17 OAJ31188.1 - 3.8e-39 134.3 0.0 5.9e-35 120.6 0.0 2.4 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 OAJ31188.1 - 1.3e-06 27.9 0.1 3e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 Peptidase C26 ASF1_hist_chap PF04729.8 OAJ31190.1 - 8.1e-57 191.1 1.2 9.5e-56 187.7 0.8 1.9 1 1 0 1 1 1 1 ASF1 like histone chaperone Sad1_UNC PF07738.8 OAJ31191.1 - 1.7e-22 79.6 0.0 1.2e-12 47.7 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal Abhydrolase_5 PF12695.2 OAJ31192.1 - 3e-24 85.4 0.0 5e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ31192.1 - 3.7e-16 59.6 1.8 2.4e-14 53.7 1.2 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ31192.1 - 3.3e-08 33.3 0.0 0.0046 16.5 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 OAJ31192.1 - 6.3e-07 28.1 0.0 0.0021 16.5 0.0 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 OAJ31192.1 - 0.00035 20.0 0.0 0.0024 17.3 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 OAJ31192.1 - 0.0016 18.2 0.1 0.018 14.7 0.0 2.4 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 OAJ31192.1 - 0.0034 16.6 0.0 0.046 12.9 0.0 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 OAJ31192.1 - 0.013 14.8 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.15 OAJ31192.1 - 0.046 13.1 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Ub-Mut7C PF14451.1 OAJ31192.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 Mut7-C ubiquitin Abhydrolase_2 PF02230.11 OAJ31192.1 - 0.17 11.3 0.0 17 4.7 0.0 2.4 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DUF1768 PF08719.6 OAJ31193.1 - 2.2e-29 102.2 0.0 2.8e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.6 OAJ31193.1 - 8.6e-05 22.0 0.0 0.00029 20.3 0.0 1.8 1 1 0 1 1 1 1 Bacteriophage protein GP30.3 zf-CSL PF05207.8 OAJ31194.1 - 1.1e-23 82.5 1.0 1.1e-23 82.5 0.7 1.4 2 0 0 2 2 2 1 CSL zinc finger zinc_ribbon_5 PF13719.1 OAJ31194.1 - 0.0014 18.1 0.8 0.0022 17.5 0.6 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 OAJ31194.1 - 0.0045 16.6 1.1 0.0072 15.9 0.8 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-RING_4 PF14570.1 OAJ31194.1 - 0.038 13.5 0.5 0.072 12.6 0.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.5 OAJ31194.1 - 0.044 13.7 0.6 0.087 12.7 0.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain U3_assoc_6 PF08640.6 OAJ31195.1 - 3.9e-13 48.9 0.5 2.7e-12 46.2 0.1 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 Mob_synth_C PF06463.8 OAJ31198.1 - 6.8e-32 109.8 0.0 2.6e-31 107.9 0.0 1.9 1 1 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 OAJ31198.1 - 2.1e-25 89.8 0.0 3.2e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 OAJ31198.1 - 5.2e-06 26.6 0.0 9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 OAJ31198.1 - 0.00019 21.4 0.0 0.00038 20.4 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain MoaC PF01967.16 OAJ31199.1 - 5.8e-41 139.3 1.7 2.1e-21 76.0 0.0 2.2 2 0 0 2 2 2 2 MoaC family SRP-alpha_N PF04086.8 OAJ31199.1 - 0.12 11.6 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Glyoxalase_3 PF13468.1 OAJ31200.1 - 7.5e-24 84.5 3.3 3.1e-14 53.2 0.0 3.6 4 0 0 4 4 4 3 Glyoxalase-like domain CPSase_L_D2 PF02786.12 OAJ31201.1 - 2e-114 380.1 0.1 1.6e-82 275.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 OAJ31201.1 - 9.1e-45 151.3 0.0 2e-44 150.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 OAJ31201.1 - 5e-44 149.4 0.0 9.3e-44 148.5 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 OAJ31201.1 - 8.8e-42 141.6 0.0 2.4e-21 75.8 0.0 3.1 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain GATase PF00117.23 OAJ31201.1 - 9.4e-42 142.6 0.0 2.4e-41 141.3 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.14 OAJ31201.1 - 4.7e-40 136.1 0.0 1e-39 135.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.19 OAJ31201.1 - 4.8e-36 124.0 0.0 9.9e-36 122.9 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 OAJ31201.1 - 2.7e-35 121.7 0.3 2.9e-20 72.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAJ31201.1 - 5.5e-21 74.6 0.0 1.6e-12 46.8 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 OAJ31201.1 - 5.4e-16 58.5 0.1 3.8e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 OAJ31201.1 - 7.4e-16 57.9 0.1 5.7e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 OAJ31201.1 - 8.1e-12 44.9 0.0 3.1e-11 43.0 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain Peptidase_C26 PF07722.8 OAJ31201.1 - 1.4e-05 24.6 0.0 0.0004 19.9 0.0 2.6 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 OAJ31201.1 - 2.5e-05 24.2 0.1 0.27 11.0 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 OAJ31201.1 - 0.0049 16.4 0.0 0.29 10.6 0.0 2.8 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 OAJ31201.1 - 0.0087 15.5 0.0 0.92 8.9 0.0 2.4 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Peptidase_C71 PF12386.3 OAJ31201.1 - 0.21 10.9 0.0 0.61 9.5 0.0 1.7 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei GMC_oxred_N PF00732.14 OAJ31202.1 - 2.5e-39 135.1 0.0 3.8e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ31202.1 - 1.7e-19 70.5 0.9 3.5e-19 69.5 0.1 2.0 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 OAJ31202.1 - 3.2e-09 36.1 1.8 1.9e-05 23.6 1.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAJ31202.1 - 1.7e-05 23.8 0.2 0.00019 20.4 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ31202.1 - 6.2e-05 22.9 0.4 0.00014 21.7 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 OAJ31202.1 - 0.00013 21.1 0.1 0.0002 20.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAJ31202.1 - 0.0007 19.5 0.1 0.004 17.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ31202.1 - 0.011 14.2 0.5 0.024 13.1 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 OAJ31202.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 OAJ31202.1 - 0.011 14.8 0.4 0.02 14.0 0.3 1.3 1 0 0 1 1 1 0 Thi4 family FliG_M PF14841.1 OAJ31202.1 - 0.015 15.3 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 FliG middle domain FAD_oxidored PF12831.2 OAJ31202.1 - 0.023 13.7 1.2 0.035 13.2 0.8 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 OAJ31202.1 - 0.076 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.11 OAJ31202.1 - 0.16 11.4 0.1 0.28 10.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DNA_ligase_A_M PF01068.16 OAJ31204.1 - 2.6e-58 196.7 0.1 4.7e-58 195.8 0.1 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 OAJ31204.1 - 2.3e-53 180.6 0.1 3.9e-53 179.8 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 OAJ31204.1 - 5.1e-25 87.7 0.0 1.5e-24 86.2 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 OAJ31204.1 - 0.0055 16.3 0.3 1.1 8.9 0.0 2.7 2 0 0 2 2 2 2 DNA ligase OB-like domain SMC_N PF02463.14 OAJ31205.1 - 9.4e-70 234.2 0.0 7.1e-68 228.1 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 OAJ31205.1 - 5.4e-20 71.5 0.7 3.3e-19 69.0 0.1 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 OAJ31205.1 - 2.7e-16 60.5 12.6 2.7e-16 60.5 8.8 6.3 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 OAJ31205.1 - 5.7e-14 52.7 8.6 1.4e-06 28.4 0.0 3.4 4 0 0 4 4 4 2 AAA domain WEMBL PF05701.6 OAJ31205.1 - 3.3e-06 25.8 44.0 3.3e-06 25.8 30.5 4.1 3 1 1 4 4 4 1 Weak chloroplast movement under blue light AAA_29 PF13555.1 OAJ31205.1 - 2.1e-05 23.9 0.1 6.2e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain FliJ PF02050.11 OAJ31205.1 - 0.0048 16.9 13.4 0.0048 16.9 9.3 9.0 5 3 4 10 10 10 1 Flagellar FliJ protein XhlA PF10779.4 OAJ31205.1 - 0.0064 16.3 3.7 0.0064 16.3 2.6 8.3 10 2 0 11 11 11 2 Haemolysin XhlA Reo_sigmaC PF04582.7 OAJ31205.1 - 0.22 10.6 28.6 0.35 10.0 1.1 5.5 4 1 2 6 6 6 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 OAJ31205.1 - 0.26 11.5 0.0 0.26 11.5 0.0 6.3 3 2 0 3 3 3 0 ABC transporter Longin PF13774.1 OAJ31206.1 - 3.2e-23 81.0 0.0 5.7e-23 80.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 OAJ31206.1 - 4e-14 51.9 0.1 8.5e-14 50.9 0.1 1.6 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 OAJ31206.1 - 0.043 13.6 0.2 0.068 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FliJ PF02050.11 OAJ31206.1 - 0.5 10.4 4.1 0.13 12.3 0.7 1.6 2 0 0 2 2 2 0 Flagellar FliJ protein AAA_2 PF07724.9 OAJ31207.1 - 2.7e-31 108.7 0.0 1.1e-23 84.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 OAJ31207.1 - 1.6e-12 47.7 0.0 3.5e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 OAJ31207.1 - 2e-11 43.6 0.0 4.4e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 OAJ31207.1 - 5.5e-05 23.2 0.6 0.00014 21.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain MCM PF00493.18 OAJ31207.1 - 7.4e-05 21.7 0.1 0.0002 20.2 0.0 1.7 2 0 0 2 2 2 1 MCM2/3/5 family AAA_5 PF07728.9 OAJ31207.1 - 8.9e-05 22.2 0.0 0.00027 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 OAJ31207.1 - 0.0001 22.4 0.1 0.00044 20.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ31207.1 - 0.00089 20.0 0.0 0.0028 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 OAJ31207.1 - 0.0084 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAJ31207.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 OAJ31207.1 - 0.024 14.5 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAJ31207.1 - 0.027 14.1 0.0 0.079 12.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 OAJ31207.1 - 0.058 12.8 0.1 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 OAJ31207.1 - 0.075 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 OAJ31207.1 - 0.089 11.9 1.3 0.58 9.2 0.0 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 OAJ31207.1 - 0.096 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 OAJ31207.1 - 0.13 12.5 0.1 0.35 11.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain 4HBT_2 PF13279.1 OAJ31208.1 - 3.2e-07 30.8 0.0 3.9e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 OAJ31208.1 - 3e-06 27.2 0.0 4.9e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 OAJ31208.1 - 0.022 13.6 0.3 0.041 12.8 0.2 1.4 2 0 0 2 2 2 0 Acyl-ACP thioesterase Pec_lyase_C PF00544.14 OAJ31209.1 - 2.1e-19 69.7 0.8 3.2e-19 69.2 0.6 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 OAJ31209.1 - 0.00011 22.0 5.7 0.00047 19.9 3.9 2.0 1 1 0 1 1 1 1 Right handed beta helix region DAO PF01266.19 OAJ31210.1 - 7e-48 163.3 0.3 1.2e-47 162.5 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase EF-hand_7 PF13499.1 OAJ31210.1 - 2.3e-06 27.6 1.0 5.2e-06 26.4 0.7 1.6 1 0 0 1 1 1 1 EF-hand domain pair FAD_binding_2 PF00890.19 OAJ31210.1 - 8.3e-06 24.9 5.5 9.3e-05 21.4 3.8 2.2 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 OAJ31210.1 - 2.2e-05 23.7 0.5 2.2e-05 23.7 0.4 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAJ31210.1 - 0.00046 20.1 0.2 0.0066 16.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 OAJ31210.1 - 0.00085 18.4 0.3 0.0027 16.8 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 OAJ31210.1 - 0.0073 16.1 0.7 0.044 13.6 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 OAJ31210.1 - 0.0088 15.3 0.4 0.02 14.2 0.3 1.6 1 0 0 1 1 1 1 EF hand GIDA PF01134.17 OAJ31210.1 - 0.017 14.0 0.2 0.15 10.8 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 OAJ31210.1 - 0.02 14.5 0.2 0.059 13.0 0.2 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 OAJ31210.1 - 0.028 14.4 0.2 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ31210.1 - 0.15 12.5 0.7 0.36 11.2 0.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.1 OAJ31210.1 - 0.18 11.4 1.6 1.7 8.2 0.1 3.0 3 1 1 4 4 4 0 EF-hand domain pair NAD_binding_8 PF13450.1 OAJ31210.1 - 2 8.4 6.1 0.26 11.3 0.4 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Topoisom_I_N PF02919.10 OAJ31211.1 - 1.1e-79 266.7 1.4 1.1e-79 266.7 1.0 3.9 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 OAJ31211.1 - 9.2e-58 195.1 0.2 9.2e-58 195.1 0.1 2.5 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 OAJ31211.1 - 2.3e-17 62.4 0.1 2.3e-14 52.8 0.0 3.1 2 0 0 2 2 2 2 C-terminal topoisomerase domain SNARE PF05739.14 OAJ31212.1 - 2.2e-16 59.2 2.3 3.2e-16 58.7 0.7 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 OAJ31212.1 - 5.3e-14 52.2 4.3 1.8e-13 50.4 0.0 2.7 2 1 1 3 3 3 1 Syntaxin Sed5p PF11416.3 OAJ31212.1 - 0.0044 16.4 0.1 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 Integral membrane protein Sed5p FlaC_arch PF05377.6 OAJ31212.1 - 0.0063 16.3 0.7 0.019 14.8 0.2 2.1 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.6 OAJ31212.1 - 0.041 14.2 1.2 2.2 8.7 0.0 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal SlyX PF04102.7 OAJ31212.1 - 0.058 13.7 0.9 0.32 11.3 0.3 2.5 2 1 0 2 2 2 0 SlyX Peripla_BP_2 PF01497.13 OAJ31212.1 - 0.085 11.9 0.9 0.2 10.7 0.4 1.7 1 1 1 2 2 2 0 Periplasmic binding protein DUF1664 PF07889.7 OAJ31212.1 - 0.17 11.6 1.0 0.75 9.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 OAJ31212.1 - 0.22 11.3 7.0 1.9 8.3 0.2 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF148 PF02520.12 OAJ31212.1 - 0.35 10.6 3.3 0.9 9.3 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF148 NPV_P10 PF05531.7 OAJ31212.1 - 5 7.4 6.3 67 3.8 0.2 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Kelch_5 PF13854.1 OAJ31213.1 - 7e-35 118.4 11.7 1.7e-08 34.2 0.3 7.0 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 OAJ31213.1 - 2e-32 110.5 24.7 1.2e-08 34.8 0.1 8.1 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 OAJ31213.1 - 3.1e-32 110.1 21.2 5.7e-08 32.4 0.1 8.3 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_1 PF01344.20 OAJ31213.1 - 3.4e-23 80.9 17.0 4e-07 29.4 2.0 6.2 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.1 OAJ31213.1 - 2e-22 78.3 14.9 4.3e-06 26.6 0.0 7.1 5 1 2 7 7 7 5 Kelch motif Kelch_2 PF07646.10 OAJ31213.1 - 1.9e-16 59.1 16.0 0.0017 18.0 0.1 7.1 6 1 0 6 6 6 5 Kelch motif RAG2 PF03089.9 OAJ31213.1 - 0.0037 16.0 0.8 1.5 7.4 0.0 3.7 4 0 0 4 4 4 1 Recombination activating protein 2 Tropomyosin_1 PF12718.2 OAJ31213.1 - 0.014 15.2 0.5 0.014 15.2 0.3 6.3 3 1 3 6 6 6 0 Tropomyosin like AAA_13 PF13166.1 OAJ31213.1 - 5.2 5.3 32.2 0.12 10.7 7.1 3.9 3 1 0 4 4 4 0 AAA domain PNRC PF15365.1 OAJ31214.1 - 2.9 7.9 6.6 9.7 6.2 3.5 2.7 2 1 0 2 2 2 0 Proline-rich nuclear receptor coactivator Vac7 PF12751.2 OAJ31215.1 - 0.00016 20.6 0.6 0.00019 20.3 0.4 1.1 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 Spt20 PF12090.3 OAJ31215.1 - 0.061 12.6 1.6 0.075 12.3 1.1 1.2 1 0 0 1 1 1 0 Spt20 family SH2_2 PF14633.1 OAJ31215.1 - 0.094 11.7 0.8 0.13 11.2 0.3 1.3 1 1 0 1 1 1 0 SH2 domain TSP9 PF11493.3 OAJ31215.1 - 0.099 13.2 2.0 0.13 12.8 0.5 1.9 1 1 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 DUF605 PF04652.11 OAJ31215.1 - 0.19 11.1 9.5 0.23 10.8 6.6 1.2 1 0 0 1 1 1 0 Vta1 like Myc_N PF01056.13 OAJ31215.1 - 0.19 10.8 6.2 0.34 10.0 4.3 1.4 1 1 0 1 1 1 0 Myc amino-terminal region Bul1_N PF04425.7 OAJ31215.1 - 0.48 8.9 3.6 0.56 8.6 2.5 1.1 1 0 0 1 1 1 0 Bul1 N terminus Tmemb_9 PF05434.6 OAJ31215.1 - 1.6 8.4 4.9 0.92 9.2 0.1 2.2 2 0 0 2 2 2 0 TMEM9 DUF4661 PF15576.1 OAJ31215.1 - 2.3 7.8 4.4 2.8 7.5 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) MRC1 PF09444.5 OAJ31215.1 - 2.3 8.5 9.3 3.7 7.8 6.5 1.3 1 0 0 1 1 1 0 MRC1-like domain Conotoxin PF02950.12 OAJ31215.1 - 4.2 8.2 9.3 3 8.6 0.8 2.5 2 0 0 2 2 2 0 Conotoxin DUF1183 PF06682.7 OAJ31215.1 - 6.1 6.3 7.6 12 5.4 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Herpes_LMP2 PF07415.6 OAJ31215.1 - 7.1 5.1 6.7 16 3.8 4.7 1.5 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Flp_Fap PF04964.9 OAJ31216.1 - 0.026 14.0 3.2 0.039 13.5 1.3 1.9 1 1 1 2 2 2 0 Flp/Fap pilin component DUF759 PF05537.6 OAJ31216.1 - 0.11 11.2 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) BRI3BP PF14965.1 OAJ31216.1 - 0.16 11.3 0.5 0.18 11.1 0.4 1.1 1 0 0 1 1 1 0 Negative regulator of p53/TP53 DUF3481 PF11980.3 OAJ31216.1 - 0.23 11.3 1.0 0.24 11.2 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) SseC PF04888.7 OAJ31216.1 - 2.3 7.4 8.4 4.2 6.6 5.8 1.4 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family PBP_sp32 PF07222.7 OAJ31217.1 - 0.17 11.0 1.2 0.19 10.8 0.8 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CPSF_A PF03178.10 OAJ31218.1 - 1.8e-79 267.1 0.0 6.3e-79 265.3 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 OAJ31218.1 - 2.4e-67 227.2 0.0 3.4e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term IN_DBD_C PF00552.16 OAJ31218.1 - 0.22 11.0 0.0 0.43 10.0 0.0 1.4 1 0 0 1 1 1 0 Integrase DNA binding domain DUF629 PF04780.7 OAJ31219.1 - 0.057 11.9 0.1 0.077 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-B_box PF00643.19 OAJ31219.1 - 0.25 11.2 3.2 0.34 10.8 2.2 1.2 1 0 0 1 1 1 0 B-box zinc finger ADH_N PF08240.7 OAJ31220.1 - 2.1e-26 91.7 1.5 3.3e-26 91.1 1.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ31220.1 - 1.3e-08 34.4 0.1 0.002 17.6 0.1 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 OAJ31220.1 - 0.0071 15.9 1.0 0.02 14.5 0.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.14 OAJ31220.1 - 0.053 12.6 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3136 PF11334.3 OAJ31220.1 - 0.063 12.6 0.0 0.26 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) Pyr_redox_3 PF13738.1 OAJ31220.1 - 0.12 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Senescence PF06911.7 OAJ31223.1 - 1.3e-28 99.9 0.5 2.2e-28 99.1 0.3 1.4 1 0 0 1 1 1 1 Senescence-associated protein DHquinase_II PF01220.14 OAJ31224.1 - 5.8e-59 197.4 0.0 7.6e-59 197.0 0.0 1.1 1 0 0 1 1 1 1 Dehydroquinase class II LRR_4 PF12799.2 OAJ31225.1 - 1.9e-36 123.1 25.3 1.1e-08 34.5 1.7 7.0 5 2 1 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ31225.1 - 8.9e-34 115.0 46.4 3.4e-08 33.0 3.0 6.2 2 1 7 9 9 9 8 Leucine rich repeat LRR_1 PF00560.28 OAJ31225.1 - 1e-17 61.4 20.6 0.12 12.4 0.4 10.9 10 2 0 10 10 10 7 Leucine Rich Repeat LRR_6 PF13516.1 OAJ31225.1 - 1.6e-12 46.0 19.0 0.22 11.6 0.0 10.0 9 2 1 10 10 10 4 Leucine Rich repeat LRR_7 PF13504.1 OAJ31225.1 - 5.8e-12 43.7 18.7 2.1 8.8 0.0 10.5 10 0 0 10 10 10 3 Leucine rich repeat LRR_9 PF14580.1 OAJ31225.1 - 4.3e-11 42.6 4.3 1.7e-05 24.4 0.2 3.7 1 1 2 3 3 3 3 Leucine-rich repeat NPHI_C PF08469.5 OAJ31225.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal Arylsulfotran_2 PF14269.1 OAJ31226.1 - 1.8e-36 125.8 0.0 4.9e-36 124.4 0.0 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 OAJ31226.1 - 7.3e-09 34.6 2.9 1.4e-08 33.7 2.0 1.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) GMC_oxred_N PF00732.14 OAJ31227.1 - 1.2e-39 136.2 1.4 9.2e-38 130.0 0.2 2.8 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ31227.1 - 5.8e-30 104.4 1.0 8.3e-30 103.9 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase Sulfotransfer_3 PF13469.1 OAJ31227.1 - 0.00015 22.7 0.4 0.00037 21.4 0.3 1.6 1 0 0 1 1 1 1 Sulfotransferase family XhlA PF10779.4 OAJ31227.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Haemolysin XhlA FHA PF00498.21 OAJ31228.1 - 3.5e-15 55.8 0.0 5.6e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 FHA domain DUF4611 PF15387.1 OAJ31228.1 - 1.5 8.9 11.0 0.037 14.1 0.7 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4611) Esterase PF00756.15 OAJ31229.1 - 0.00019 20.9 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 OAJ31229.1 - 0.014 15.1 0.2 0.038 13.7 0.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ31229.1 - 0.082 12.4 1.0 0.1 12.0 0.1 1.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold Ribosomal_S9 PF00380.14 OAJ31229.1 - 0.088 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S9/S16 Herpes_capsid PF06112.6 OAJ31229.1 - 6.3 6.8 9.2 17 5.4 6.4 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Pox_MCEL PF03291.11 OAJ31230.1 - 1.2e-68 231.4 0.0 1.6e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.1 OAJ31230.1 - 1.7e-11 43.9 0.0 2.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ31230.1 - 5.4e-09 35.9 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ31230.1 - 1.2e-08 35.2 0.0 2.8e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ31230.1 - 1.9e-08 34.8 0.0 4.2e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ31230.1 - 2e-06 28.0 0.0 4.2e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ31230.1 - 3.5e-06 27.3 0.0 9.7e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 OAJ31230.1 - 0.0003 19.8 0.0 0.0017 17.3 0.0 1.9 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family MTS PF05175.9 OAJ31230.1 - 0.00096 18.5 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 OAJ31230.1 - 0.022 13.9 0.1 0.072 12.1 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MetW PF07021.7 OAJ31230.1 - 0.53 9.6 0.0 0.89 8.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FAD_binding_3 PF01494.14 OAJ31231.1 - 3e-16 59.4 0.0 8.1e-16 58.0 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAJ31231.1 - 0.0087 16.0 0.1 0.018 15.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 OAJ31231.1 - 0.0092 14.8 0.0 0.034 12.9 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.22 OAJ31231.1 - 0.011 16.1 0.2 0.074 13.4 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ31231.1 - 0.011 14.6 0.1 0.82 8.5 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.11 OAJ31231.1 - 0.022 14.2 0.1 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 7tm_4 PF13853.1 OAJ31233.1 - 0.0029 17.4 5.6 0.0045 16.8 3.9 1.2 1 0 0 1 1 1 1 Olfactory receptor Pkinase PF00069.20 OAJ31235.1 - 1.2e-05 24.5 0.0 0.053 12.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ31235.1 - 0.00045 19.3 0.0 0.21 10.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Asn_synthase PF00733.16 OAJ31238.1 - 4e-68 229.6 0.0 9.2e-68 228.4 0.0 1.6 2 0 0 2 2 2 1 Asparagine synthase GATase_7 PF13537.1 OAJ31238.1 - 3.9e-37 126.7 0.0 6.4e-37 126.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 OAJ31238.1 - 3.2e-29 101.5 0.0 1.8e-28 99.1 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 OAJ31238.1 - 3.3e-06 26.0 0.0 0.0033 16.1 0.0 2.7 1 1 2 3 3 3 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 OAJ31238.1 - 1.1e-05 24.8 0.0 2.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 OAJ31238.1 - 0.053 12.4 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 NAD synthase QueC PF06508.8 OAJ31238.1 - 0.2 10.9 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC DUF1933 PF09147.5 OAJ31238.1 - 0.25 10.7 0.0 0.41 10.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) PQ-loop PF04193.9 OAJ31239.1 - 9.5e-36 121.1 6.3 9.5e-18 63.5 0.9 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 OAJ31239.1 - 0.045 13.6 0.4 0.045 13.6 0.2 2.2 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange WD40 PF00400.27 OAJ31241.1 - 1.9e-50 167.0 13.3 4.1e-09 35.9 0.2 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat Tannase PF07519.6 OAJ31241.1 - 4.4e-47 160.8 0.0 1.5e-37 129.4 0.0 2.5 1 1 1 2 2 2 2 Tannase and feruloyl esterase Nup160 PF11715.3 OAJ31241.1 - 0.013 13.6 0.2 4.8 5.1 0.1 3.5 1 1 2 3 3 3 0 Nucleoporin Nup120/160 DUF1264 PF06884.6 OAJ31242.1 - 8.2e-46 155.5 0.0 1.2e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) UDPG_MGDP_dh_N PF03721.9 OAJ31243.1 - 5e-60 202.0 0.3 1.3e-59 200.7 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 OAJ31243.1 - 5.2e-34 116.5 0.1 2.2e-32 111.3 0.0 2.8 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 OAJ31243.1 - 8.4e-32 109.2 0.0 1.6e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 OAJ31243.1 - 0.00083 19.1 0.1 0.067 12.9 0.0 2.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 OAJ31243.1 - 0.004 17.5 0.3 4.3 7.8 0.1 3.1 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent SET PF00856.23 OAJ31245.1 - 0.00023 21.5 0.0 0.0047 17.2 0.0 2.8 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 OAJ31245.1 - 0.016 15.1 0.2 0.098 12.5 0.1 2.0 1 1 0 1 1 1 0 Rubisco LSMT substrate-binding Thioredoxin_7 PF13899.1 OAJ31246.1 - 0.00018 21.4 0.0 0.00052 19.9 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 OAJ31246.1 - 0.00053 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain Radial_spoke_3 PF06098.6 OAJ31246.1 - 1.8 7.4 10.2 3.4 6.5 6.6 1.6 2 0 0 2 2 2 0 Radial spoke protein 3 SIS PF01380.17 OAJ31247.1 - 7.2e-13 48.2 0.0 2.8e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.1 OAJ31247.1 - 0.00012 21.7 0.0 0.0042 16.8 0.0 2.3 1 1 0 1 1 1 1 SIS domain Glyco_hydro_38 PF01074.17 OAJ31248.1 - 4.5e-77 259.0 0.6 7.5e-77 258.2 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 OAJ31248.1 - 2.6e-56 191.3 0.0 4.1e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 OAJ31248.1 - 3.4e-25 88.0 0.0 8e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain DUF1720 PF08226.6 OAJ31249.1 - 6.9 6.8 15.6 0.2 11.7 3.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1720) Defensin_2 PF01097.13 OAJ31251.1 - 0.035 13.8 1.4 0.095 12.4 1.0 1.7 1 0 0 1 1 1 0 Arthropod defensin NDUFA12 PF05071.11 OAJ31252.1 - 3e-10 40.5 0.1 5e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 F-box PF00646.28 OAJ31253.1 - 5.6e-08 32.2 2.2 8.5e-07 28.4 0.1 2.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 OAJ31253.1 - 0.00012 21.6 2.3 0.00012 21.6 1.6 2.2 3 0 0 3 3 3 1 F-box-like MFS_1 PF07690.11 OAJ31254.1 - 6.7e-30 103.9 23.6 6.7e-30 103.9 16.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 OAJ31254.1 - 0.49 8.3 7.1 21 3.0 4.9 2.2 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Pkinase_C PF00433.19 OAJ31255.1 - 0.00034 21.0 0.1 0.00052 20.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Pea-VEAacid PF08111.6 OAJ31255.1 - 0.12 12.4 0.4 0.27 11.4 0.3 1.5 1 0 0 1 1 1 0 Pea-VEAacid family MFS_1 PF07690.11 OAJ31256.1 - 0.00021 20.1 3.8 0.00031 19.5 2.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1768 PF08719.6 OAJ31257.1 - 0.00012 21.8 0.0 0.00015 21.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) SP_C-Propep PF08999.5 OAJ31258.1 - 0.045 13.2 0.2 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide NUDIX PF00293.23 OAJ31259.1 - 1.7e-12 47.0 0.0 1.3e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain Golgin_A5 PF09787.4 OAJ31259.1 - 0.11 11.0 0.8 0.16 10.4 0.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Lon_C PF05362.8 OAJ31260.1 - 2.1e-66 223.1 0.2 4.7e-66 222.0 0.1 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 OAJ31260.1 - 1.3e-31 109.8 0.0 2.7e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 OAJ31260.1 - 1.6e-21 76.9 0.0 5.7e-21 75.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 OAJ31260.1 - 5.9e-07 29.0 0.0 1.8e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 OAJ31260.1 - 3.1e-06 27.2 0.0 5.6e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 OAJ31260.1 - 6.7e-06 25.8 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 OAJ31260.1 - 4.6e-05 23.4 0.2 0.00048 20.1 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.6 OAJ31260.1 - 6.1e-05 21.8 0.0 0.0001 21.1 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 OAJ31260.1 - 0.001 19.8 0.3 0.0036 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAJ31260.1 - 0.0012 18.9 0.1 0.038 14.1 0.0 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAJ31260.1 - 0.0017 17.4 0.0 0.0085 15.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 OAJ31260.1 - 0.0024 17.7 0.0 0.0057 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ31260.1 - 0.0071 16.6 1.4 0.012 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 OAJ31260.1 - 0.021 14.2 0.0 0.058 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 OAJ31260.1 - 0.024 14.3 1.9 8.6 5.9 0.0 3.4 2 1 0 3 3 3 0 Archaeal ATPase TIP49 PF06068.8 OAJ31260.1 - 0.03 13.0 3.1 0.91 8.1 0.0 2.6 3 0 0 3 3 3 0 TIP49 C-terminus RNA_helicase PF00910.17 OAJ31260.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 OAJ31260.1 - 0.053 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 OAJ31260.1 - 0.06 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 GUCT PF08152.7 OAJ31260.1 - 0.089 12.7 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 GUCT (NUC152) domain MotA_activ PF09114.5 OAJ31261.1 - 0.022 14.4 12.4 5.9 6.7 0.1 5.6 3 1 4 7 7 7 0 Transcription factor MotA, activation domain DUF4423 PF14394.1 OAJ31261.1 - 0.038 13.5 0.2 25 4.3 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4423) DUF2540 PF10802.3 OAJ31261.1 - 0.06 13.0 1.8 3.2 7.4 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2540) DrsE_2 PF13686.1 OAJ31261.1 - 0.071 12.8 0.6 19 4.9 0.0 3.9 4 1 1 5 5 5 0 DsrE/DsrF/DrsH-like family DAG_kinase_N PF14513.1 OAJ31261.1 - 3.6 7.7 10.0 11 6.2 0.1 5.3 3 2 3 7 7 7 0 Diacylglycerol kinase N-terminus Strep_pep PF14404.1 OAJ31261.1 - 5.3 7.3 21.7 11 6.3 0.1 7.1 4 3 3 8 8 8 0 Ribosomally synthesized peptide in Streptomyces species CRAL_TRIO PF00650.15 OAJ31262.1 - 1.5e-27 96.0 0.0 2.7e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ31262.1 - 7e-10 38.8 0.4 2.3e-09 37.2 0.3 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 OAJ31262.1 - 3.2e-07 30.3 0.0 5.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Brr6_like_C_C PF10104.4 OAJ31263.1 - 2.7e-34 117.6 0.1 3.5e-34 117.2 0.1 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF1768 PF08719.6 OAJ31264.1 - 3.5e-24 85.3 0.0 1.4e-23 83.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1768) DUF1768 PF08719.6 OAJ31265.1 - 6.1e-12 45.5 1.4 1.1e-06 28.4 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF1768) Translin PF01997.11 OAJ31269.1 - 6.4e-41 140.1 0.2 8.2e-41 139.8 0.1 1.1 1 0 0 1 1 1 1 Translin family BLOC1_2 PF10046.4 OAJ31269.1 - 0.02 15.0 0.1 0.46 10.6 0.0 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mad3_BUB1_I PF08311.7 OAJ31270.1 - 1.8e-32 111.8 0.2 2.8e-32 111.1 0.2 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 OAJ31270.1 - 1.4e-11 44.0 0.0 2.7e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ31270.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Cellulase PF00150.13 OAJ31271.1 - 7.9e-18 64.6 4.7 2.9e-17 62.8 3.2 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CDP-OH_P_transf PF01066.16 OAJ31272.1 - 2.1e-16 60.0 3.6 2.3e-16 59.9 2.0 1.5 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase EST1_DNA_bind PF10373.4 OAJ31273.1 - 1.3e-31 109.8 0.0 1.2e-30 106.7 0.0 2.4 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 OAJ31273.1 - 1.5e-07 31.4 0.0 8.6e-07 29.0 0.0 2.3 2 1 0 2 2 2 1 Telomerase activating protein Est1 TPR_11 PF13414.1 OAJ31273.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 TPR repeat Secretin_N_2 PF07655.8 OAJ31273.1 - 0.036 14.4 0.3 0.036 14.4 0.2 3.6 4 0 0 4 4 4 0 Secretin N-terminal domain NAD_binding_11 PF14833.1 OAJ31274.1 - 4.7e-32 110.6 0.1 9.6e-32 109.6 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 OAJ31274.1 - 1.9e-30 105.8 0.0 4.2e-30 104.7 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 OAJ31274.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2OG-FeII_Oxy_3 PF13640.1 OAJ31275.1 - 0.00023 21.6 0.1 0.00048 20.5 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ31275.1 - 0.00081 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily VID27 PF08553.5 OAJ31276.1 - 4.8e-07 28.4 0.4 1.8e-06 26.5 0.2 1.7 1 1 0 1 1 1 1 VID27 cytoplasmic protein Ras PF00071.17 OAJ31277.1 - 1e-53 181.0 0.0 1.2e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ31277.1 - 6.5e-17 62.1 0.0 8.4e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ31277.1 - 6e-06 25.6 0.0 9e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ31277.1 - 0.0015 17.9 0.0 0.018 14.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF367 PF04034.8 OAJ31278.1 - 7.5e-42 141.9 0.0 1e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 OAJ31278.1 - 1.2e-13 50.3 0.1 2.3e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SDA1 PF05285.7 OAJ31278.1 - 1.7 7.8 19.1 10 5.2 10.4 2.1 2 0 0 2 2 2 0 SDA1 DUF2201_N PF13203.1 OAJ31278.1 - 7.7 5.5 11.5 4.4 6.3 5.0 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain ICL PF00463.16 OAJ31279.1 - 3.7e-254 843.7 1.5 4.2e-254 843.6 1.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 OAJ31279.1 - 1.2e-09 37.7 0.0 2.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 OAJ31279.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Clr2 PF10383.4 OAJ31280.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 Plasmodium_Vir PF05795.6 OAJ31282.1 - 0.095 11.8 0.1 0.81 8.8 0.0 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Nucleoplasmin PF03066.10 OAJ31282.1 - 0.65 9.5 3.6 0.65 9.5 0.8 2.1 2 0 0 2 2 2 0 Nucleoplasmin SVM_signal PF12113.3 OAJ31282.1 - 1.6 8.6 2.9 2.6 7.9 2.0 1.3 1 0 0 1 1 1 0 SVM protein signal sequence Kinesin PF00225.18 OAJ31283.1 - 9.1e-106 353.3 0.1 2.3e-105 352.0 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain PI-PLC-X PF00388.14 OAJ31284.1 - 0.032 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain SUI1 PF01253.17 OAJ31285.1 - 4.3e-11 42.4 0.0 8.2e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 SPATIAL PF15256.1 OAJ31285.1 - 0.062 13.3 0.2 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 SPATIAL GA PF01468.12 OAJ31285.1 - 2.2 8.5 7.8 0.15 12.2 1.1 2.2 3 0 0 3 3 3 0 GA module BRO1 PF03097.13 OAJ31286.1 - 6.1e-94 314.8 0.5 1.1e-93 313.9 0.0 1.6 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 OAJ31286.1 - 4.2e-63 213.0 14.1 1.8e-62 211.0 9.8 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV GST_N_3 PF13417.1 OAJ31287.1 - 6.6e-10 39.0 0.0 1.2e-09 38.2 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAJ31287.1 - 9.5e-07 28.9 0.0 1.5e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ31287.1 - 5.5e-06 26.2 0.0 1.1e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ31287.1 - 7.5e-05 22.6 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ31287.1 - 0.00021 21.6 0.0 0.00032 21.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ31287.1 - 0.0035 17.2 0.0 0.0082 16.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aminotran_3 PF00202.16 OAJ31288.1 - 1.9e-34 119.0 0.0 1.5e-15 56.8 0.0 3.2 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.1 OAJ31288.1 - 2.6e-26 92.4 0.0 6.1e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Gcd10p PF04189.8 OAJ31289.1 - 4.9e-69 232.7 0.0 7.3e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family RNase_H2_suC PF08615.6 OAJ31289.1 - 0.067 13.0 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Ribosomal_S10 PF00338.17 OAJ31290.1 - 2.3e-31 107.4 0.2 2.8e-31 107.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Shisa PF13908.1 OAJ31291.1 - 4.2 7.4 6.6 7.5 6.6 4.6 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PMT PF02366.13 OAJ31293.1 - 1.8e-74 250.2 17.2 3.3e-74 249.3 11.9 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 OAJ31293.1 - 1.6e-11 44.0 2.3 4.9e-10 39.2 0.6 2.7 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 OAJ31293.1 - 1e-05 25.5 11.2 1e-05 25.5 7.8 2.8 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase WD40 PF00400.27 OAJ31294.1 - 5.7e-55 181.3 13.0 1.8e-11 43.4 0.0 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat PRP4 PF08799.6 OAJ31294.1 - 3.2e-13 48.6 3.0 5.7e-13 47.8 2.1 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 OAJ31294.1 - 0.00013 21.1 0.1 0.0078 15.3 0.0 3.0 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 OAJ31294.1 - 0.19 9.8 1.8 4.8 5.1 0.0 2.8 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Ribosomal_L24e PF01246.15 OAJ31295.1 - 6.2e-31 106.0 2.3 6.2e-31 106.0 1.6 1.8 2 1 0 2 2 2 1 Ribosomal protein L24e Flu_M1 PF00598.14 OAJ31295.1 - 0.05 13.0 0.2 0.07 12.5 0.2 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) DUF2116 PF09889.4 OAJ31295.1 - 1.1 9.0 5.7 4.2 7.2 0.5 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Glyco_hydro_cc PF11790.3 OAJ31296.1 - 2.9e-49 167.6 1.2 4.3e-49 167.1 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core TFIIA PF03153.8 OAJ31297.1 - 0.0022 17.9 8.6 0.0022 17.9 6.0 3.4 1 1 2 3 3 3 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 OAJ31297.1 - 0.64 7.8 31.4 1.1 7.1 10.7 2.2 2 0 0 2 2 2 0 Nop14-like family DUF724 PF05266.9 OAJ31297.1 - 5.3 6.6 8.3 15 5.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Myosin_tail_1 PF01576.14 OAJ31298.1 - 5.1e-15 54.3 228.3 9.9e-05 20.2 35.4 6.6 1 1 4 5 5 5 5 Myosin tail Tropomyosin PF00261.15 OAJ31298.1 - 0.00012 21.3 22.1 0.00012 21.3 15.3 7.9 2 1 4 7 7 7 4 Tropomyosin Filament PF00038.16 OAJ31298.1 - 2.1 7.7 190.3 0.25 10.7 29.8 9.4 1 1 5 7 7 7 0 Intermediate filament protein Nucleopor_Nup85 PF07575.8 OAJ31299.1 - 4.6e-70 236.4 0.0 4.8e-37 127.4 0.0 2.3 2 1 0 2 2 2 2 Nup85 Nucleoporin Lsr2 PF11774.3 OAJ31299.1 - 3.3 7.6 7.7 1.4 8.8 0.2 3.0 3 0 0 3 3 3 0 Lsr2 DUF1935 PF09149.5 OAJ31300.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) Glyco_hydro_16 PF00722.16 OAJ31301.1 - 1.8e-05 24.1 0.0 3.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1640 PF07798.6 OAJ31302.1 - 2.6e-65 219.7 2.4 3.1e-65 219.5 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.13 OAJ31302.1 - 0.2 11.3 1.7 1.4 8.7 1.2 2.4 1 1 0 1 1 1 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 OAJ31302.1 - 2.4 8.1 5.4 8 6.4 0.5 2.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) NUDIX PF00293.23 OAJ31303.1 - 3.5e-07 29.9 0.1 1.3e-05 24.8 0.1 2.6 2 1 0 2 2 2 1 NUDIX domain Zds_C PF08632.5 OAJ31304.1 - 4.3e-21 74.0 0.6 7.9e-21 73.1 0.4 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Guanylate_kin PF00625.16 OAJ31305.1 - 8.5e-55 185.0 0.0 1e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 OAJ31305.1 - 5.7e-08 32.9 0.3 4.2e-07 30.1 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ31305.1 - 4.4e-07 30.1 0.0 1.1e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 OAJ31305.1 - 1.4e-05 24.3 0.0 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAJ31305.1 - 5e-05 24.1 0.0 8e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ31305.1 - 0.00013 22.2 0.0 0.00035 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 OAJ31305.1 - 0.00018 21.0 0.0 0.0011 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA-like domain AAA_33 PF13671.1 OAJ31305.1 - 0.00021 21.2 0.1 0.00049 19.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 OAJ31305.1 - 0.00028 21.2 0.0 0.00045 20.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Arch_ATPase PF01637.13 OAJ31305.1 - 0.00052 19.7 0.0 0.00074 19.2 0.0 1.4 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 OAJ31305.1 - 0.00083 19.2 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 OAJ31305.1 - 0.0039 16.8 0.0 0.0081 15.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 OAJ31305.1 - 0.0042 17.0 0.0 0.0066 16.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 OAJ31305.1 - 0.0052 16.9 0.0 0.0083 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA helicase MobB PF03205.9 OAJ31305.1 - 0.0056 16.3 0.0 0.011 15.4 0.0 1.5 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 OAJ31305.1 - 0.0064 16.9 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein NTPase_1 PF03266.10 OAJ31305.1 - 0.0069 16.1 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 NTPase AAA_29 PF13555.1 OAJ31305.1 - 0.0095 15.4 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 OAJ31305.1 - 0.014 15.3 0.2 0.052 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 OAJ31305.1 - 0.043 12.7 0.0 0.088 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PTS_IIB PF02302.12 OAJ31305.1 - 0.047 14.1 0.0 0.34 11.4 0.0 2.3 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit Septin PF00735.13 OAJ31305.1 - 0.047 12.6 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_30 PF13604.1 OAJ31305.1 - 0.048 13.2 0.0 0.077 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 OAJ31305.1 - 0.052 13.7 0.0 0.078 13.1 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAJ31305.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AFG1_ATPase PF03969.11 OAJ31305.1 - 0.064 12.0 0.0 0.25 10.1 0.0 1.9 2 0 0 2 2 2 0 AFG1-like ATPase Rad17 PF03215.10 OAJ31305.1 - 0.064 11.9 0.0 0.087 11.4 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein IstB_IS21 PF01695.12 OAJ31305.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ArgK PF03308.11 OAJ31305.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.4 1 1 0 1 1 1 0 ArgK protein AAA_21 PF13304.1 OAJ31305.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 OAJ31305.1 - 0.11 11.0 0.0 0.22 10.1 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.1 OAJ31305.1 - 0.11 12.0 0.0 0.35 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 OAJ31305.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain NB-ARC PF00931.17 OAJ31305.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DAP3 PF10236.4 OAJ31305.1 - 0.15 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 PNP_UDP_1 PF01048.15 OAJ31306.1 - 4.1e-30 104.4 5.3 4.2e-29 101.1 3.7 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily Na_H_Exchanger PF00999.16 OAJ31308.1 - 4.3e-51 173.6 10.8 5.7e-51 173.2 7.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 OAJ31308.1 - 0.024 14.5 1.5 0.11 12.4 0.0 2.5 2 0 0 2 2 2 0 YrhC-like protein DHquinase_I PF01487.10 OAJ31309.1 - 8.1e-41 140.1 0.0 2.2e-40 138.6 0.0 1.8 1 1 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 OAJ31309.1 - 4.3e-21 75.4 0.0 7.2e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 OAJ31309.1 - 0.002 18.9 0.0 0.0042 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ31309.1 - 0.27 11.5 0.0 0.56 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ureide_permease PF07168.6 OAJ31310.1 - 0.15 10.6 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Ureide permease QueF_N PF14819.1 OAJ31311.1 - 4e-06 26.8 0.4 0.71 9.9 0.1 3.4 3 0 0 3 3 3 3 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term DUF1018 PF06252.7 OAJ31311.1 - 0.089 13.3 0.3 65 4.0 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1018) AIRC PF00731.15 OAJ31312.1 - 7.5e-57 190.8 1.3 1.7e-56 189.6 0.9 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 OAJ31312.1 - 8.7e-53 178.1 0.0 2.3e-30 105.2 0.0 2.3 1 1 1 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.1 OAJ31312.1 - 5e-09 36.1 0.1 1e-07 31.8 0.0 2.4 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 OAJ31312.1 - 5.4e-05 22.5 0.0 0.00017 20.9 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 OAJ31312.1 - 0.001 18.5 0.0 0.0029 17.0 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.14 OAJ31312.1 - 0.0018 17.4 0.0 0.0036 16.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 OAJ31312.1 - 0.015 14.9 0.1 0.044 13.4 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HTH_9 PF08221.6 OAJ31313.1 - 3.7e-19 68.3 0.3 5e-07 29.5 0.0 4.5 4 0 0 4 4 4 4 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 OAJ31313.1 - 2.2e-10 40.5 0.0 4.4e-08 32.9 0.0 3.1 2 1 0 2 2 2 2 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.12 OAJ31313.1 - 6.7e-07 28.7 0.0 0.0004 19.8 0.0 3.1 3 0 0 3 3 3 2 TFIIE alpha subunit SNF2_N PF00176.18 OAJ31314.1 - 2.5e-34 118.4 0.0 1.1e-33 116.3 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ31314.1 - 0.00035 20.3 0.0 0.00086 19.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FUSC_2 PF13515.1 OAJ31315.1 - 3.3e-21 75.5 10.2 3.3e-21 75.5 7.1 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 OAJ31315.1 - 8.2e-17 60.9 2.0 4.1e-11 42.1 0.2 2.2 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.7 OAJ31315.1 - 1.8e-10 39.9 11.5 2.7e-10 39.3 2.6 2.8 2 1 0 2 2 2 2 Fusaric acid resistance protein family DUF2421 PF10334.4 OAJ31315.1 - 1.1e-08 35.0 0.3 3.4e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) PMT PF02366.13 OAJ31316.1 - 3.4e-68 229.6 17.9 6.4e-68 228.7 12.4 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 OAJ31316.1 - 4e-30 104.7 0.1 6.6e-30 104.0 0.1 1.4 1 0 0 1 1 1 1 MIR domain Histone PF00125.19 OAJ31318.1 - 0.00021 21.3 0.0 0.00028 20.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF4095 PF13338.1 OAJ31318.1 - 0.018 15.1 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4095) DUF4218 PF13960.1 OAJ31319.1 - 0.00021 20.7 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) TPR_2 PF07719.12 OAJ31320.1 - 0.021 14.7 5.6 1.6 8.8 0.6 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ31320.1 - 0.03 14.2 11.3 0.38 10.7 1.6 5.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ31320.1 - 0.13 11.8 2.9 12 5.6 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ31320.1 - 1.6 8.3 10.7 0.28 10.8 1.4 3.8 5 0 0 5 5 5 0 TPR repeat DIOX_N PF14226.1 OAJ31321.1 - 2.6e-14 53.7 0.0 5.1e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAJ31321.1 - 2.4e-13 50.2 0.0 4e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NmrA PF05368.8 OAJ31322.1 - 1.7e-15 56.9 0.0 1.9e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAJ31322.1 - 0.0011 19.0 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAJ31322.1 - 0.024 13.3 0.1 0.034 12.8 0.1 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 OAJ31322.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DeoC PF01791.4 OAJ31324.1 - 2.6e-34 118.5 2.5 6.2e-33 114.0 1.7 2.0 1 1 0 1 1 1 1 DeoC/LacD family aldolase RebB PF11747.3 OAJ31324.1 - 0.03 14.1 7.7 0.12 12.2 5.3 2.1 1 0 0 1 1 1 0 Killing trait UPF0121 PF03661.8 OAJ31325.1 - 1.4e-20 73.5 7.1 3.2e-20 72.4 4.9 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF2101 PF09874.4 OAJ31325.1 - 0.06 12.8 0.1 0.06 12.8 0.1 2.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2101) SNF2_N PF00176.18 OAJ31326.1 - 1.8e-71 240.4 0.3 2.9e-71 239.6 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ31326.1 - 2.5e-14 52.8 0.0 9.8e-14 50.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ31326.1 - 3.7e-08 33.4 0.1 1.3e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ31326.1 - 3.3e-05 23.4 0.0 0.00011 21.7 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSA PF07529.8 OAJ31326.1 - 0.0017 18.0 8.1 0.0017 18.0 5.6 2.7 2 1 1 3 3 3 1 HSA HDA2-3 PF11496.3 OAJ31326.1 - 0.012 14.4 0.5 2.6 6.7 0.1 2.5 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 OAJ31327.1 - 2.4e-08 33.7 0.0 4.2e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Fer2 PF00111.22 OAJ31329.1 - 8.8e-09 35.0 1.9 5.8e-08 32.3 1.3 2.0 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain SNase PF00565.12 OAJ31330.1 - 4.8e-45 152.2 0.9 2.4e-17 63.1 0.0 7.2 7 0 0 7 7 7 5 Staphylococcal nuclease homologue TUDOR PF00567.19 OAJ31330.1 - 3.7e-20 71.9 0.0 7.1e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Tudor domain DUF4537 PF15057.1 OAJ31330.1 - 0.0062 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Agenet PF05641.7 OAJ31330.1 - 0.053 13.6 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 Agenet domain WD40 PF00400.27 OAJ31331.1 - 1.5e-60 199.0 19.6 5.3e-12 45.1 1.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 OAJ31331.1 - 3e-07 29.8 0.0 0.0043 16.5 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Proteasome_A_N PF10584.4 OAJ31331.1 - 0.046 13.0 0.1 13 5.2 0.0 3.1 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Abhydrolase_1 PF00561.15 OAJ31332.1 - 2.1e-13 50.3 0.0 8.8e-12 45.0 0.0 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 OAJ31332.1 - 7.6e-13 48.2 0.0 1.7e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 OAJ31332.1 - 6.1e-07 29.5 2.2 2e-06 27.8 0.4 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF836 PF05768.9 OAJ31333.1 - 3.2e-10 40.1 0.0 4.3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 OAJ31333.1 - 0.0084 16.2 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Fcf1 PF04900.7 OAJ31334.1 - 6.9e-13 48.5 0.0 2.1e-12 47.0 0.0 1.8 1 1 0 1 1 1 1 Fcf1 CENP-U PF13097.1 OAJ31334.1 - 0.046 13.6 3.0 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit mRNA_triPase PF02940.10 OAJ31335.1 - 3.3e-45 154.4 0.1 3.9e-45 154.2 0.1 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain SH3_9 PF14604.1 OAJ31336.1 - 2.6e-15 55.7 0.0 5.5e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 OAJ31336.1 - 2.2e-14 53.5 0.0 4.8e-13 49.2 0.0 2.3 2 0 0 2 2 2 1 PH domain SH3_1 PF00018.23 OAJ31336.1 - 2.9e-12 45.7 0.4 6.7e-12 44.6 0.3 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ31336.1 - 1.9e-09 36.8 0.0 4.8e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 OAJ31336.1 - 2.5e-07 30.4 0.0 4.5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 OAJ31336.1 - 0.00069 19.7 0.0 0.002 18.2 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF3104 PF11302.3 OAJ31336.1 - 0.13 11.6 0.0 0.35 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Ste50p-SAM PF09235.5 OAJ31336.1 - 0.19 11.8 0.3 0.37 10.8 0.2 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Nucleoplasmin PF03066.10 OAJ31337.1 - 0.018 14.5 12.2 0.018 14.5 8.5 2.2 2 0 0 2 2 2 0 Nucleoplasmin Sigma70_ner PF04546.8 OAJ31337.1 - 0.079 12.5 19.2 0.019 14.5 5.7 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Spt5_N PF11942.3 OAJ31337.1 - 0.081 13.5 30.0 0.64 10.6 12.7 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Na_trans_assoc PF06512.8 OAJ31337.1 - 0.34 10.8 10.3 0.48 10.3 7.2 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated MIP-T3 PF10243.4 OAJ31337.1 - 0.56 8.6 15.0 0.64 8.4 10.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FAM176 PF14851.1 OAJ31337.1 - 0.56 9.8 13.3 0.53 9.9 2.6 2.2 2 0 0 2 2 2 0 FAM176 family Prothymosin PF03247.9 OAJ31337.1 - 1.3 9.1 36.7 0.26 11.4 12.3 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family Pox_RNA_Pol_19 PF05320.7 OAJ31337.1 - 2.9 7.6 17.1 2.2 8.0 5.8 2.1 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Spore_coat_CotO PF14153.1 OAJ31337.1 - 4.1 6.8 11.3 1.7 8.0 1.3 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Vfa1 PF08432.5 OAJ31337.1 - 5.3 7.0 11.8 0.95 9.4 2.0 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Ribosomal_60s PF00428.14 OAJ31337.1 - 9.7 6.6 22.7 0.46 10.9 2.8 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein KGG PF10685.4 OAJ31338.1 - 7.3e-07 28.9 2.2 7.3e-07 28.9 1.6 4.1 3 1 0 3 3 3 2 Stress-induced bacterial acidophilic repeat motif RNA_pol_3_Rpc31 PF11705.3 OAJ31338.1 - 3.2 7.6 8.9 3.8 7.3 6.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SPX PF03105.14 OAJ31339.1 - 9.6e-47 160.0 1.0 1.3e-46 159.6 0.7 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 OAJ31339.1 - 8.2e-31 107.3 37.7 1.1e-30 106.9 26.1 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 OAJ31339.1 - 2.3e-21 75.7 37.9 3e-14 52.3 12.0 2.2 1 1 1 2 2 2 2 Citrate transporter DEAD PF00270.24 OAJ31341.1 - 1.2e-19 70.4 0.1 3.6e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ31341.1 - 0.00068 19.5 0.1 0.0093 15.8 0.0 2.7 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DUF4228 PF14009.1 OAJ31341.1 - 0.015 15.4 2.0 0.015 15.4 1.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4228) FNIP_C PF14638.1 OAJ31341.1 - 0.016 14.5 0.2 0.032 13.5 0.1 1.5 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus CENP-Q PF13094.1 OAJ31341.1 - 0.041 13.9 1.6 0.073 13.0 1.1 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Metallophos PF00149.23 OAJ31342.1 - 4.1e-18 65.5 0.1 1.9e-09 37.2 0.0 2.7 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase Helicase_C PF00271.26 OAJ31342.1 - 5e-15 55.1 0.1 9.7e-15 54.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Metallophos_C PF14008.1 OAJ31342.1 - 2e-13 50.1 0.0 6.1e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 OAJ31342.1 - 5.6e-07 28.4 0.0 1.9e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 PhoD-like phosphatase fn3 PF00041.16 OAJ31342.1 - 0.0023 17.9 1.4 0.0058 16.7 0.9 1.7 1 0 0 1 1 1 1 Fibronectin type III domain Metallophos_2 PF12850.2 OAJ31342.1 - 0.0075 16.1 0.0 0.046 13.5 0.0 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain RQC PF09382.5 OAJ31342.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 RQC domain Mur_ligase_M PF08245.7 OAJ31343.1 - 4.9e-05 23.4 0.0 0.18 11.8 0.0 2.8 2 1 0 2 2 2 2 Mur ligase middle domain FtsJ PF01728.14 OAJ31344.1 - 3.9e-48 163.8 0.0 5.5e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 OAJ31344.1 - 5.8e-05 23.6 0.1 0.0012 19.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ31344.1 - 0.00032 20.3 0.0 0.0019 17.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ31344.1 - 0.0011 19.2 0.0 0.0039 17.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ31344.1 - 0.014 15.1 0.0 0.045 13.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain CbiA PF01656.18 OAJ31344.1 - 0.028 13.8 0.3 0.098 12.0 0.1 1.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ubie_methyltran PF01209.13 OAJ31344.1 - 0.17 10.9 0.0 0.5 9.4 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family WD40 PF00400.27 OAJ31345.1 - 6.7e-48 158.9 15.7 3.2e-09 36.3 0.0 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat PQQ_3 PF13570.1 OAJ31345.1 - 0.031 14.5 0.8 30 5.0 0.0 3.8 3 0 0 3 3 3 0 PQQ-like domain Nup160 PF11715.3 OAJ31345.1 - 0.032 12.3 1.6 0.29 9.2 0.1 2.7 1 1 1 3 3 3 0 Nucleoporin Nup120/160 CLTH PF10607.4 OAJ31345.1 - 0.048 13.3 0.1 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain EF-hand_7 PF13499.1 OAJ31346.1 - 5e-06 26.5 0.2 5e-06 26.5 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 OAJ31346.1 - 8.5e-06 25.2 0.2 0.072 13.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 OAJ31346.1 - 1.3e-05 24.2 0.1 0.088 12.1 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.27 OAJ31346.1 - 2.7e-05 23.1 0.2 0.14 11.5 0.0 2.8 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.4 OAJ31346.1 - 0.2 11.6 3.7 1.5 8.8 0.0 3.6 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region ABC_ATPase PF09818.4 OAJ31347.1 - 7.8e-134 446.6 0.0 6.4e-133 443.5 0.0 2.0 1 1 0 1 1 1 1 Predicted ATPase of the ABC class AAA_28 PF13521.1 OAJ31347.1 - 0.047 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.3 OAJ31347.1 - 0.17 10.8 0.5 1.4 7.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) ABC_tran PF00005.22 OAJ31347.1 - 0.28 11.4 1.7 0.99 9.6 0.9 1.9 1 1 1 2 2 2 0 ABC transporter Cullin PF00888.17 OAJ31349.1 - 2.5e-104 349.9 0.0 5.9e-104 348.7 0.0 1.5 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 OAJ31349.1 - 2.1e-20 72.3 0.7 5.7e-20 70.9 0.5 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF2407 PF10302.4 OAJ31349.1 - 0.096 12.8 0.3 0.36 11.0 0.2 2.0 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain AAR2 PF05282.6 OAJ31350.1 - 2.3e-35 122.2 0.0 1.3e-34 119.7 0.0 2.1 1 1 1 2 2 2 1 AAR2 protein DUF4414 PF14377.1 OAJ31350.1 - 2 8.3 9.9 0.62 10.0 0.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4414) zf-RING_2 PF13639.1 OAJ31351.1 - 7.1e-08 32.1 7.1 1.4e-07 31.2 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAJ31351.1 - 2.7e-06 27.3 1.0 6.6e-06 26.1 0.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 OAJ31351.1 - 0.0011 18.7 1.5 0.0026 17.5 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 OAJ31351.1 - 0.0048 16.8 3.7 0.011 15.6 2.5 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 OAJ31351.1 - 0.0074 16.3 6.1 0.017 15.1 4.3 1.7 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.20 OAJ31351.1 - 0.011 15.3 8.4 0.02 14.5 5.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 OAJ31351.1 - 0.28 10.9 3.5 0.56 9.9 2.4 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 OAJ31351.1 - 0.53 10.3 8.9 1.1 9.3 6.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 OAJ31351.1 - 2.6 7.8 5.2 4.7 6.9 3.6 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.1 OAJ31351.1 - 4.7 6.9 5.2 8.6 6.1 3.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ31351.1 - 6.1 6.6 6.5 10 5.9 4.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain SynMuv_product PF06047.6 OAJ31352.1 - 2.1e-47 159.2 3.5 6.2e-47 157.6 2.5 1.8 1 0 0 1 1 1 1 Ras-induced vulval development antagonist Ribosomal_L32p PF01783.18 OAJ31353.1 - 1.8e-13 50.4 6.6 4.1e-13 49.3 4.6 1.6 1 0 0 1 1 1 1 Ribosomal L32p protein family DUF164 PF02591.10 OAJ31353.1 - 0.14 12.0 2.6 2.3 8.1 0.2 2.4 1 1 1 2 2 2 0 Putative zinc ribbon domain BTB PF00651.26 OAJ31354.1 - 1.3e-05 25.0 0.0 0.013 15.5 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Polyketide_cyc PF03364.15 OAJ31355.1 - 6e-23 81.2 0.2 1.5e-22 79.9 0.1 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 OAJ31355.1 - 0.001 19.2 0.2 0.024 14.8 0.1 2.3 1 1 1 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Pheromone PF08015.6 OAJ31355.1 - 0.058 14.2 6.2 0.15 12.9 4.3 1.8 1 0 0 1 1 1 0 Fungal mating-type pheromone Myb_DNA-bind_6 PF13921.1 OAJ31356.1 - 1.1e-12 47.8 0.0 0.00012 22.1 0.0 4.5 4 1 1 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 OAJ31356.1 - 3.1e-10 39.9 0.8 0.00064 19.7 0.0 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain FAP PF07174.6 OAJ31357.1 - 0.013 14.7 32.4 0.024 13.9 22.5 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) adh_short PF00106.20 OAJ31359.1 - 5.3e-27 94.7 1.7 5.3e-14 52.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ31359.1 - 1.7e-21 77.0 0.2 6.2e-21 75.2 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ31359.1 - 1.3e-12 47.7 0.4 3.1e-05 23.6 0.2 2.3 2 0 0 2 2 2 2 KR domain 3HCDH_N PF02737.13 OAJ31359.1 - 0.00036 20.2 0.6 0.00068 19.3 0.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 OAJ31359.1 - 0.037 14.1 0.0 0.088 12.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 OAJ31359.1 - 0.074 12.2 0.2 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 OAJ31359.1 - 0.11 13.0 0.1 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.16 OAJ31359.1 - 0.17 11.4 0.1 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain E1-E2_ATPase PF00122.15 OAJ31360.1 - 1.3e-61 207.5 4.5 2.9e-61 206.4 1.9 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAJ31360.1 - 8.4e-46 155.7 4.8 5.4e-45 153.1 1.6 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ31360.1 - 1.3e-29 104.1 0.0 9.7e-23 81.6 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ31360.1 - 3.8e-19 68.4 0.0 7e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 OAJ31360.1 - 2.7e-18 65.1 0.0 6.5e-18 63.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 OAJ31360.1 - 1.5e-12 48.0 0.0 7.5e-12 45.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ31360.1 - 8.1e-05 22.3 1.8 0.0061 16.1 1.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 OAJ31360.1 - 0.018 15.2 0.0 0.066 13.4 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Translin PF01997.11 OAJ31361.1 - 1.1e-40 139.3 0.5 3.9e-38 131.0 0.3 2.4 1 1 0 1 1 1 1 Translin family THEG PF14912.1 OAJ31361.1 - 0.00043 20.7 1.0 0.00043 20.7 0.7 2.3 2 0 0 2 2 2 1 Testicular haploid expressed repeat Adeno_PIX PF03955.9 OAJ31361.1 - 6.1 7.4 6.1 19 5.8 0.0 3.0 3 1 0 3 3 3 0 Adenovirus hexon-associated protein (IX) DAO PF01266.19 OAJ31363.1 - 2e-41 142.1 0.3 3e-41 141.5 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ31363.1 - 0.00014 21.8 0.1 0.00031 20.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.10 OAJ31363.1 - 0.01 14.0 0.1 0.024 12.8 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.7 OAJ31363.1 - 0.018 13.9 0.1 0.068 12.0 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 OAJ31363.1 - 0.029 14.7 0.0 0.065 13.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 OAJ31363.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.1 OAJ31363.1 - 0.076 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SnoaL_2 PF12680.2 OAJ31363.1 - 0.14 12.5 0.0 0.46 10.9 0.0 1.8 1 0 0 1 1 1 0 SnoaL-like domain GDA1_CD39 PF01150.12 OAJ31364.1 - 7.3e-72 242.2 0.0 6.5e-59 199.5 0.0 3.1 3 0 0 3 3 3 3 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 OAJ31364.1 - 0.043 13.0 0.0 0.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Ppx/GppA phosphatase family DUF605 PF04652.11 OAJ31365.1 - 9.3e-87 291.8 22.9 8.2e-86 288.7 15.9 2.0 1 1 0 1 1 1 1 Vta1 like TPR_11 PF13414.1 OAJ31366.1 - 1.8e-09 37.0 7.6 0.011 15.3 0.0 5.7 5 1 0 5 5 5 2 TPR repeat TPR_12 PF13424.1 OAJ31366.1 - 0.00046 20.0 16.3 1.3 9.0 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ31366.1 - 0.0005 20.4 13.8 25 5.8 0.2 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ31366.1 - 0.026 14.8 7.4 9.7 6.6 0.6 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ31366.1 - 0.035 14.0 7.8 1.6 8.8 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ31366.1 - 0.096 12.9 0.1 5.4 7.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ31366.1 - 0.1 12.2 0.3 18 5.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ31366.1 - 1.9 9.2 9.2 8.7 7.1 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat E1_dh PF00676.15 OAJ31367.1 - 5.1e-83 278.2 0.0 6.2e-83 277.9 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 OAJ31367.1 - 0.08 11.8 0.0 0.21 10.4 0.0 1.6 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Grp1_Fun34_YaaH PF01184.14 OAJ31368.1 - 3e-77 258.6 16.1 3.6e-77 258.4 11.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF155 PF02582.9 OAJ31369.1 - 8.3e-48 162.5 0.0 1.2e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 REV PF00424.13 OAJ31370.1 - 0.059 13.2 0.3 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Peptidase_S10 PF00450.17 OAJ31371.1 - 2.4e-76 257.5 0.1 3.2e-76 257.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PLU-1 PF08429.6 OAJ31372.1 - 1.4e-46 158.9 1.8 2.2e-46 158.3 1.2 1.3 1 0 0 1 1 1 1 PLU-1-like protein JmjC PF02373.17 OAJ31372.1 - 8.2e-42 142.0 0.4 1.6e-41 141.1 0.3 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 OAJ31372.1 - 7e-22 76.8 45.1 2.8e-12 46.1 2.3 4.5 4 0 0 4 4 4 3 PHD-finger ARID PF01388.16 OAJ31372.1 - 1.6e-20 72.7 0.0 3.3e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 OAJ31372.1 - 3e-12 46.4 0.2 1.1e-11 44.5 0.2 2.1 1 0 0 1 1 1 1 C5HC2 zinc finger JmjN PF02375.12 OAJ31372.1 - 5.8e-12 44.9 0.9 1.1e-11 43.9 0.6 1.5 1 0 0 1 1 1 1 jmjN domain PHD_2 PF13831.1 OAJ31372.1 - 2 7.8 28.3 1.7 8.0 0.2 4.1 4 0 0 4 4 4 0 PHD-finger Prok-RING_1 PF14446.1 OAJ31372.1 - 2.8 7.7 22.5 3.1 7.5 0.4 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 AAA PF00004.24 OAJ31373.1 - 4.9e-41 140.0 0.0 7.8e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ31373.1 - 6.4e-07 29.5 0.3 0.0026 17.9 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 OAJ31373.1 - 9.9e-06 25.5 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 OAJ31373.1 - 3e-05 23.0 0.0 6.7e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 OAJ31373.1 - 0.00019 21.4 0.1 0.0016 18.4 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 OAJ31373.1 - 0.00035 20.3 0.4 0.003 17.2 0.2 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 OAJ31373.1 - 0.00092 18.3 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 OAJ31373.1 - 0.0016 18.3 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ31373.1 - 0.0039 18.0 0.5 0.011 16.5 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_3 PF07726.6 OAJ31373.1 - 0.0041 16.7 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 OAJ31373.1 - 0.0043 16.4 0.6 0.74 9.1 0.1 2.4 1 1 1 2 2 2 1 AAA domain KaiC PF06745.8 OAJ31373.1 - 0.0061 15.7 0.1 0.18 10.8 0.0 2.3 1 1 1 2 2 2 1 KaiC AAA_33 PF13671.1 OAJ31373.1 - 0.0063 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ31373.1 - 0.007 16.0 0.3 0.015 15.0 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 OAJ31373.1 - 0.01 16.1 0.0 0.029 14.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 OAJ31373.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 OAJ31373.1 - 0.02 13.9 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 OAJ31373.1 - 0.03 13.2 0.0 0.063 12.1 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain TIP49 PF06068.8 OAJ31373.1 - 0.036 12.7 0.0 0.068 11.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_28 PF13521.1 OAJ31373.1 - 0.037 13.9 0.4 0.08 12.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 OAJ31373.1 - 0.064 12.9 0.2 0.43 10.2 0.0 2.1 1 1 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 OAJ31373.1 - 0.074 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 OAJ31373.1 - 0.077 11.9 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 OAJ31373.1 - 0.11 11.6 0.1 0.37 9.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 OAJ31373.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Histone PF00125.19 OAJ31373.1 - 0.14 12.3 0.2 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 AAA_24 PF13479.1 OAJ31373.1 - 0.14 11.7 0.1 0.35 10.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain Mis12 PF05859.7 OAJ31374.1 - 4.2e-17 62.3 0.5 1.4e-16 60.5 0.3 1.9 1 1 0 1 1 1 1 Mis12 protein Myb_DNA-binding PF00249.26 OAJ31375.1 - 5.3e-14 52.0 0.0 6.9e-06 26.0 0.0 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ31375.1 - 4.2e-11 42.7 0.0 5.2e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Nop16 PF09420.5 OAJ31375.1 - 0.076 13.1 0.0 12 5.9 0.0 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 TIM PF00121.13 OAJ31376.1 - 8.1e-93 309.9 0.5 9e-93 309.8 0.4 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 OAJ31376.1 - 0.0062 15.8 0.2 0.077 12.2 0.0 2.0 1 1 1 2 2 2 1 CutC family Cyclin_N PF00134.18 OAJ31377.1 - 4.2e-10 39.2 0.1 1.2e-07 31.3 0.0 2.7 4 0 0 4 4 4 2 Cyclin, N-terminal domain RecO_C PF02565.10 OAJ31377.1 - 0.082 12.7 0.3 2 8.3 0.0 2.4 2 1 0 2 2 2 0 Recombination protein O C terminal AT_hook PF02178.14 OAJ31378.1 - 0.053 13.2 8.8 0.33 10.7 2.5 2.6 2 0 0 2 2 2 0 AT hook motif Hid1 PF12722.2 OAJ31378.1 - 4.9 4.6 31.8 6.4 4.3 22.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4045 PF13254.1 OAJ31378.1 - 5.5 6.1 26.8 12 4.9 18.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3808 PF10300.4 OAJ31379.1 - 7.3e-83 278.6 0.0 2.1e-82 277.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.12 OAJ31379.1 - 1.9e-05 24.2 1.2 0.048 13.5 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ31379.1 - 0.00014 21.3 0.5 0.0022 17.6 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ31379.1 - 0.00051 19.6 1.6 0.31 10.6 0.0 3.4 3 1 0 3 3 3 2 TPR repeat TPR_6 PF13174.1 OAJ31379.1 - 0.018 15.4 0.6 4.5 7.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ31379.1 - 0.092 13.4 0.3 48 4.7 0.1 3.5 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ31379.1 - 0.12 12.3 4.2 3.7 7.5 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ31379.1 - 0.12 12.2 0.3 14 5.7 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ31379.1 - 0.13 11.9 0.9 1.3 8.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Phage_holin_2 PF04550.7 OAJ31380.1 - 0.18 11.8 10.9 10 6.2 0.2 4.2 2 2 2 4 4 4 0 Phage holin family 2 PROCN PF08083.6 OAJ31382.1 - 1.6e-207 688.9 5.6 2.4e-207 688.3 3.9 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 OAJ31382.1 - 1.6e-126 420.2 0.7 2.6e-126 419.5 0.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 OAJ31382.1 - 1.1e-91 304.4 1.3 2.9e-91 303.0 0.9 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 OAJ31382.1 - 5.2e-78 259.9 2.4 5.2e-78 259.9 1.7 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 OAJ31382.1 - 2.5e-61 205.2 0.0 4.7e-61 204.3 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 OAJ31382.1 - 1.2e-41 140.4 0.0 2.7e-41 139.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 OAJ31382.1 - 3.4e-35 120.4 0.0 6.9e-35 119.4 0.0 1.5 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 OAJ31382.1 - 0.0095 15.6 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2370 PF10176.4 OAJ31383.1 - 1.5e-68 230.6 0.0 6.5e-68 228.5 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 OAJ31383.1 - 0.051 13.7 4.3 0.094 12.9 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF202) BAF1_ABF1 PF04684.8 OAJ31383.1 - 0.092 11.5 0.1 0.2 10.4 0.0 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor LSM PF01423.17 OAJ31386.1 - 1.9e-16 59.3 0.1 2.3e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF3106 PF11304.3 OAJ31388.1 - 0.0041 17.5 1.0 0.0041 17.5 0.7 3.0 4 0 0 4 4 4 1 Protein of unknown function (DUF3106) LRR_4 PF12799.2 OAJ31389.1 - 2.6e-13 49.2 18.1 4.5e-06 26.1 0.6 5.5 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ31389.1 - 8e-10 38.3 8.4 8e-10 38.3 5.8 4.0 6 0 0 6 6 6 1 Leucine rich repeat LRR_1 PF00560.28 OAJ31389.1 - 0.00028 20.4 15.8 0.52 10.5 0.6 7.5 8 1 1 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.1 OAJ31389.1 - 0.00091 19.0 17.2 9.1 6.6 0.3 7.5 8 0 0 8 8 8 2 Leucine Rich repeat LRR_9 PF14580.1 OAJ31389.1 - 0.0079 15.7 1.0 0.16 11.4 0.3 2.4 2 1 0 2 2 2 1 Leucine-rich repeat Phage_integrase PF00589.17 OAJ31390.1 - 0.00021 21.0 0.0 0.00072 19.2 0.0 1.8 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.12 OAJ31390.1 - 0.023 14.8 0.0 0.094 12.8 0.0 2.1 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain HIT PF01230.18 OAJ31391.1 - 7.7e-23 80.8 0.1 1.3e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 OAJ31391.1 - 7.7e-11 42.2 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 OAJ31391.1 - 3.3e-06 26.7 0.0 5.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 NGP1NT PF08153.7 OAJ31392.1 - 1e-41 141.9 0.0 2.4e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 OAJ31392.1 - 2.4e-17 62.9 0.0 4.3e-14 52.4 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase Arf PF00025.16 OAJ31392.1 - 0.00028 20.1 0.1 0.041 13.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.13 OAJ31392.1 - 0.00089 18.5 0.1 0.002 17.4 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 OAJ31392.1 - 0.0021 17.2 0.0 0.0047 16.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 OAJ31392.1 - 0.01 15.2 0.2 0.41 10.0 0.0 3.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 OAJ31392.1 - 0.28 11.0 0.0 0.28 11.0 0.0 4.5 5 1 1 6 6 6 0 Dynamin family MSC PF09402.5 OAJ31393.1 - 3.1e-36 124.7 0.0 3.2e-19 68.8 0.0 4.1 2 2 0 2 2 2 2 Man1-Src1p-C-terminal domain DUF1421 PF07223.6 OAJ31393.1 - 5.7 6.6 45.6 0.51 10.0 28.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1421) Zn_clus PF00172.13 OAJ31394.1 - 0.00016 21.4 3.1 0.00041 20.1 2.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltrn_RNA_3 PF02598.12 OAJ31395.1 - 3e-74 250.0 0.0 5.4e-74 249.1 0.0 1.4 1 1 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 OAJ31395.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 SpoU rRNA Methylase family Bromodomain PF00439.20 OAJ31396.1 - 1.5e-24 85.6 0.1 3e-24 84.7 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 OAJ31396.1 - 7.5e-09 35.6 0.1 1.7e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAJ31396.1 - 3.8e-08 33.2 0.0 1.6e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Linker_histone PF00538.14 OAJ31397.1 - 9.5e-18 64.0 0.9 1.2e-17 63.7 0.0 1.6 2 0 0 2 2 2 1 linker histone H1 and H5 family PBP1_TM PF14812.1 OAJ31397.1 - 0.51 10.6 5.0 0.79 10.0 1.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mito_fiss_reg PF05308.6 OAJ31397.1 - 0.62 9.3 12.2 0.087 12.1 2.4 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator SR-25 PF10500.4 OAJ31397.1 - 2 7.8 22.9 2.1 7.7 10.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AFT PF08731.6 OAJ31397.1 - 2.8 8.1 5.7 2 8.6 1.9 2.1 2 0 0 2 2 2 0 Transcription factor AFT CAP_N PF01213.14 OAJ31397.1 - 3.1 7.0 14.9 0.031 13.5 3.4 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Transglut_i_TM PF14400.1 OAJ31397.1 - 5.1 6.5 9.0 0.38 10.2 0.1 2.2 2 0 0 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices ICMT PF04140.9 OAJ31398.1 - 3.6e-27 94.4 0.2 6.3e-27 93.6 0.1 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 OAJ31398.1 - 8.1e-13 48.4 1.9 2e-12 47.1 1.3 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 OAJ31398.1 - 0.00011 21.6 0.2 0.00015 21.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 OAJ31398.1 - 0.0043 15.6 0.2 0.0077 14.8 0.2 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family NnrU PF07298.6 OAJ31398.1 - 0.021 14.2 0.5 0.021 14.2 0.3 2.0 2 1 0 2 2 2 0 NnrU protein RRP7 PF12923.2 OAJ31399.1 - 0.068 13.1 0.4 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) PIN_4 PF13638.1 OAJ31400.1 - 4.5e-05 23.5 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 PIN domain DNA_pol_viral_N PF00242.12 OAJ31400.1 - 0.94 8.4 4.7 1.5 7.8 3.3 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Clat_adaptor_s PF01217.15 OAJ31401.1 - 5.3e-20 71.5 0.8 7.1e-20 71.1 0.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DNA_mis_repair PF01119.14 OAJ31402.1 - 2.2e-31 107.8 0.0 3.6e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 OAJ31402.1 - 3.5e-12 46.1 0.0 1e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 OAJ31402.1 - 1.2e-10 41.1 0.0 5.9e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nop14 PF04147.7 OAJ31402.1 - 7.9e-05 20.7 20.1 0.00012 20.2 13.9 1.2 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.8 OAJ31402.1 - 0.00024 20.7 20.0 0.00045 19.9 13.8 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Daxx PF03344.10 OAJ31402.1 - 0.0024 16.4 23.8 0.0044 15.5 16.5 1.4 1 0 0 1 1 1 1 Daxx Family CDC45 PF02724.9 OAJ31402.1 - 0.017 13.1 16.2 0.029 12.4 11.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 OAJ31402.1 - 0.018 14.3 20.5 0.032 13.5 14.2 1.3 1 0 0 1 1 1 0 SDA1 DUF1510 PF07423.6 OAJ31402.1 - 0.33 10.3 17.0 0.57 9.5 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 OAJ31402.1 - 0.46 9.9 9.3 0.79 9.1 6.5 1.3 1 0 0 1 1 1 0 Spore coat protein CotO TFIIA PF03153.8 OAJ31402.1 - 0.49 10.2 24.4 0.046 13.6 13.9 1.5 2 0 0 2 2 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.6 OAJ31402.1 - 0.58 9.6 20.2 0.95 8.9 14.0 1.4 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.7 OAJ31402.1 - 0.78 8.9 16.1 1.5 8.0 11.2 1.4 1 0 0 1 1 1 0 NOA36 protein TFIIF_alpha PF05793.7 OAJ31402.1 - 0.99 7.6 24.8 1.8 6.8 17.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) VID27 PF08553.5 OAJ31402.1 - 1.9 6.5 17.4 2.8 6.0 12.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Lin-8 PF03353.10 OAJ31402.1 - 2 7.6 9.6 4.3 6.5 6.6 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ycf1 PF05758.7 OAJ31402.1 - 3 5.4 4.8 3.9 5.0 3.3 1.1 1 0 0 1 1 1 0 Ycf1 BUD22 PF09073.5 OAJ31402.1 - 3.3 6.6 23.5 5.6 5.9 16.3 1.3 1 0 0 1 1 1 0 BUD22 eIF-3c_N PF05470.7 OAJ31402.1 - 4 5.4 9.5 6.4 4.7 6.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Mpp10 PF04006.7 OAJ31402.1 - 4.3 5.5 27.2 6.2 5.0 18.9 1.1 1 0 0 1 1 1 0 Mpp10 protein DCP1 PF06058.8 OAJ31404.1 - 4.9e-16 58.8 0.0 5.1e-08 33.0 0.0 2.7 2 1 0 2 2 2 2 Dcp1-like decapping family adh_short PF00106.20 OAJ31405.1 - 4.4e-07 29.9 0.1 9.1e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ31405.1 - 4.6e-06 26.5 0.0 7.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 OAJ31405.1 - 0.0002 21.0 0.3 0.00031 20.4 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 OAJ31405.1 - 0.00076 19.8 1.2 0.0045 17.3 0.5 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 OAJ31405.1 - 0.0042 16.7 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 KR domain ApbA PF02558.11 OAJ31405.1 - 0.089 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CsbD PF05532.7 OAJ31407.1 - 8.8e-19 66.9 16.6 6e-10 38.6 3.4 2.0 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.7 OAJ31407.1 - 0.00085 19.3 1.6 0.0016 18.4 0.7 1.8 1 1 0 1 1 1 1 Heat shock protein 9/12 UCH PF00443.24 OAJ31408.1 - 3.4e-61 206.7 0.0 4.5e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ31408.1 - 1.1e-35 123.5 3.0 1.1e-26 93.9 0.1 2.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 OAJ31408.1 - 0.00064 19.0 0.6 0.08 12.2 0.8 2.3 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Baculo_ME53 PF06061.6 OAJ31408.1 - 0.0071 15.3 1.5 0.01 14.8 1.1 1.1 1 0 0 1 1 1 1 Baculoviridae ME53 DDE_Tnp_4 PF13359.1 OAJ31409.1 - 2.5e-24 85.6 0.0 4.2e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease YrbL-PhoP_reg PF10707.4 OAJ31409.1 - 4.9e-05 22.7 0.0 0.00011 21.5 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pinin_SDK_memA PF04696.8 OAJ31410.1 - 0.021 14.4 16.1 0.063 12.8 11.1 1.9 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region His_Phos_2 PF00328.17 OAJ31412.1 - 1.9e-29 103.1 0.0 2.3e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Aminotran_MocR PF12897.2 OAJ31412.1 - 0.041 12.4 0.0 0.061 11.8 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase zf-FCS PF06467.9 OAJ31414.1 - 0.007 15.9 3.4 0.012 15.1 2.3 1.4 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif TnpB_IS66 PF05717.8 OAJ31414.1 - 0.16 11.4 0.0 0.81 9.1 0.0 2.1 2 0 0 2 2 2 0 IS66 Orf2 like protein DUF581 PF04570.9 OAJ31414.1 - 0.25 10.6 2.1 0.59 9.4 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF581) DUF4604 PF15377.1 OAJ31415.1 - 2.1e-16 60.5 26.4 4.1e-16 59.5 18.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) Med19 PF10278.4 OAJ31415.1 - 9.5 5.8 18.3 1.8 8.2 0.8 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 ATP-synt_ab PF00006.20 OAJ31416.1 - 3e-62 209.9 0.0 4.1e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 OAJ31416.1 - 1.5e-16 60.9 0.0 3e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 OAJ31416.1 - 1.5e-11 44.3 0.3 2.7e-11 43.5 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 OAJ31416.1 - 0.002 18.0 0.1 0.004 17.0 0.1 1.5 1 0 0 1 1 1 1 HAS barrel domain DUF561 PF04481.7 OAJ31416.1 - 0.046 12.6 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Cellulase PF00150.13 OAJ31417.1 - 4.6e-06 26.0 0.1 6.5e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PBP_like_2 PF12849.2 OAJ31420.1 - 0.0021 17.5 0.9 0.0027 17.2 0.5 1.3 1 1 0 1 1 1 1 PBP superfamily domain ADIP PF11559.3 OAJ31420.1 - 0.0071 16.2 3.6 0.0071 16.2 2.5 1.5 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF342 PF03961.8 OAJ31420.1 - 0.052 11.9 0.3 0.065 11.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Filament PF00038.16 OAJ31420.1 - 0.27 10.6 6.4 0.35 10.3 4.4 1.1 1 0 0 1 1 1 0 Intermediate filament protein DUF591 PF04569.9 OAJ31420.1 - 0.46 10.5 5.8 1.7 8.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function SPATA24 PF15175.1 OAJ31420.1 - 0.61 9.7 3.6 8.6 6.0 0.3 2.2 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 Striatin PF08232.7 OAJ31421.1 - 7.7e-18 65.1 1.0 1.2e-12 48.3 0.3 2.3 1 1 1 2 2 2 2 Striatin family G-alpha PF00503.15 OAJ31421.1 - 0.057 12.1 0.0 0.085 11.5 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Kelch_4 PF13418.1 OAJ31422.1 - 0.0015 18.2 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_5 PF13854.1 OAJ31422.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Kelch motif Bacteriocin_IIc PF10439.4 OAJ31423.1 - 9.1 6.4 14.0 16 5.7 9.7 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_OmpA PF13436.1 OAJ31423.1 - 9.4 5.9 19.1 0.35 10.5 9.6 1.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Myosin_head PF00063.16 OAJ31424.1 - 8.9e-227 754.4 3.0 1.5e-226 753.7 2.1 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 OAJ31424.1 - 2e-41 141.5 0.0 3.8e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 OAJ31424.1 - 1.9e-10 39.9 0.2 4e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ31424.1 - 6.5e-10 38.4 0.1 1.6e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ31424.1 - 1.3e-05 24.6 0.0 4.1e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 OAJ31424.1 - 0.0083 16.2 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAJ31424.1 - 0.037 13.1 0.1 0.078 12.0 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 OAJ31424.1 - 0.051 12.8 0.4 5.1 6.3 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_17 PF13207.1 OAJ31424.1 - 0.055 14.2 0.0 0.18 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAJ31424.1 - 0.17 11.5 0.1 0.34 10.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain IQ PF00612.22 OAJ31424.1 - 4.1 7.3 6.6 1.5 8.6 1.0 2.6 1 1 1 2 2 2 0 IQ calmodulin-binding motif MIT PF04212.13 OAJ31425.1 - 1.1e-05 25.1 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain SH3BP5 PF05276.9 OAJ31425.1 - 0.31 10.3 0.1 0.47 9.7 0.1 1.2 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Sugar_tr PF00083.19 OAJ31427.1 - 1.8e-114 382.8 15.6 2.5e-114 382.3 10.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ31427.1 - 9.3e-27 93.6 33.5 5.4e-26 91.1 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NUFIP1 PF10453.4 OAJ31428.1 - 1.7e-11 43.4 0.3 3.9e-11 42.2 0.2 1.6 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) SR-25 PF10500.4 OAJ31428.1 - 1.4 8.2 29.0 2.9 7.3 16.0 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SAPS PF04499.10 OAJ31428.1 - 1.8 7.1 6.5 2.4 6.7 4.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 OAJ31428.1 - 3.7 5.3 26.7 5 4.9 18.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 OAJ31428.1 - 6.2 4.7 16.9 8.4 4.2 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PLDc_2 PF13091.1 OAJ31429.1 - 1.3e-11 44.3 0.0 1.8e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 OAJ31429.1 - 3.8e-05 23.3 4.1 0.085 12.6 0.0 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif 3Beta_HSD PF01073.14 OAJ31430.1 - 8e-60 201.9 0.0 7.2e-56 188.9 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAJ31430.1 - 2.1e-24 86.2 0.0 3.2e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ31430.1 - 8.9e-13 48.6 0.0 1.9e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAJ31430.1 - 1.2e-11 44.0 0.0 6.3e-08 31.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 OAJ31430.1 - 3.1e-07 30.4 0.0 8.4e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 OAJ31430.1 - 8.6e-06 24.8 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 OAJ31430.1 - 0.00065 19.4 0.0 0.0027 17.3 0.0 2.0 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.13 OAJ31430.1 - 0.0041 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.10 OAJ31430.1 - 0.0049 15.8 0.1 0.023 13.6 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 OAJ31430.1 - 0.023 13.9 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family DNA_pol_B_exo1 PF03104.14 OAJ31430.1 - 0.035 12.9 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain UBA_3 PF09288.5 OAJ31430.1 - 0.066 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain PNP_UDP_1 PF01048.15 OAJ31430.1 - 0.11 11.4 0.0 0.24 10.3 0.0 1.6 2 0 0 2 2 2 0 Phosphorylase superfamily Strep_his_triad PF04270.8 OAJ31430.1 - 0.11 12.2 0.3 0.37 10.5 0.1 2.0 2 0 0 2 2 2 0 Streptococcal histidine triad protein Pribosyltran PF00156.22 OAJ31431.1 - 5.7e-07 29.3 0.0 1.3e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain DHOase PF12890.2 OAJ31431.1 - 0.04 13.5 0.1 0.22 11.2 0.0 2.2 1 1 0 1 1 1 0 Dihydro-orotase-like Cofilin_ADF PF00241.15 OAJ31432.1 - 5.4e-12 45.7 0.0 1.5e-05 24.8 0.0 2.6 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Secretin_N PF03958.12 OAJ31432.1 - 0.059 13.5 6.0 0.61 10.3 0.0 3.8 4 0 0 4 4 4 0 Bacterial type II/III secretion system short domain DUF2040 PF09745.4 OAJ31433.1 - 3.4e-30 104.4 21.0 3.4e-30 104.4 14.6 2.8 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Transferase PF02458.10 OAJ31433.1 - 0.094 11.1 1.5 0.12 10.7 1.1 1.3 1 0 0 1 1 1 0 Transferase family CENP-I PF07778.6 OAJ31433.1 - 0.12 10.5 1.0 0.22 9.6 0.7 1.3 1 0 0 1 1 1 0 Mis6 CAF-1_p150 PF11600.3 OAJ31433.1 - 0.47 9.7 32.7 0.5 9.7 6.2 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA PF00004.24 OAJ31435.1 - 3.3e-84 279.7 0.0 9.7e-42 142.3 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAJ31435.1 - 5.4e-14 52.0 0.1 3.2e-06 26.9 0.0 4.7 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 OAJ31435.1 - 5.5e-13 48.4 0.0 4.1e-06 26.0 0.0 3.0 4 0 0 4 4 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 OAJ31435.1 - 2.2e-12 47.3 1.1 0.00072 19.5 0.1 3.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 OAJ31435.1 - 5e-11 42.8 0.1 0.00012 22.2 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 OAJ31435.1 - 1.2e-09 38.9 0.0 0.00017 22.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAJ31435.1 - 2e-08 33.8 4.2 0.017 14.4 0.1 4.6 3 2 1 4 4 3 2 AAA domain TIP49 PF06068.8 OAJ31435.1 - 6.3e-08 31.7 0.1 0.00037 19.3 0.0 2.5 3 0 0 3 3 3 2 TIP49 C-terminus AAA_19 PF13245.1 OAJ31435.1 - 1.1e-07 31.5 1.3 0.00012 21.7 0.0 4.0 2 1 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 OAJ31435.1 - 1.5e-07 31.3 0.0 0.0032 17.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 OAJ31435.1 - 3.3e-07 29.5 0.0 0.00054 19.1 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_2 PF07724.9 OAJ31435.1 - 1e-06 28.7 0.0 0.041 13.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 OAJ31435.1 - 1.4e-06 27.8 0.0 0.02 14.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.1 OAJ31435.1 - 5.9e-06 26.2 0.0 0.0055 16.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 OAJ31435.1 - 2.6e-05 24.3 0.0 0.32 11.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 OAJ31435.1 - 3.2e-05 23.2 2.5 0.084 12.0 0.0 2.8 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 OAJ31435.1 - 6.6e-05 22.9 0.1 0.14 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 OAJ31435.1 - 0.00011 22.4 0.0 0.0068 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 OAJ31435.1 - 0.00025 21.1 0.0 0.3 11.1 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 OAJ31435.1 - 0.00047 19.8 0.1 0.041 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 OAJ31435.1 - 0.0011 17.7 0.1 0.19 10.3 0.0 3.0 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 OAJ31435.1 - 0.0018 17.9 0.0 4 7.0 0.0 3.4 3 1 1 4 4 3 1 NACHT domain AAA_3 PF07726.6 OAJ31435.1 - 0.0028 17.2 0.0 2 8.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 OAJ31435.1 - 0.0028 16.7 0.0 1.8 7.5 0.0 3.1 4 0 0 4 4 3 1 KaiC Sigma54_activat PF00158.21 OAJ31435.1 - 0.0042 16.5 0.2 6.7 6.1 0.0 3.9 3 1 0 3 3 3 0 Sigma-54 interaction domain NTPase_1 PF03266.10 OAJ31435.1 - 0.0048 16.6 0.4 0.84 9.3 0.0 3.8 2 2 2 4 4 4 1 NTPase ABC_tran PF00005.22 OAJ31435.1 - 0.0094 16.2 0.0 0.73 10.1 0.0 3.0 2 0 0 2 2 2 1 ABC transporter ATP-synt_ab PF00006.20 OAJ31435.1 - 0.0097 15.4 0.1 5.7 6.3 0.0 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.1 OAJ31435.1 - 0.011 15.3 0.0 0.26 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 OAJ31435.1 - 0.013 14.7 0.3 0.51 9.5 0.0 2.6 3 0 0 3 3 2 0 PhoH-like protein Parvo_NS1 PF01057.12 OAJ31435.1 - 0.023 13.5 0.0 3.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 OAJ31435.1 - 0.037 13.7 0.0 8.3 6.0 0.0 3.2 2 1 1 3 3 3 0 Archaeal ATPase SKI PF01202.17 OAJ31435.1 - 0.066 13.0 0.0 9.7 6.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase DUF815 PF05673.8 OAJ31435.1 - 0.16 10.8 0.0 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DAP3 PF10236.4 OAJ31435.1 - 0.19 10.6 0.0 0.65 8.8 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Peptidase_M13_N PF05649.8 OAJ31436.1 - 7.6e-88 295.1 0.0 9.4e-88 294.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 OAJ31436.1 - 1e-54 184.8 0.0 1.6e-54 184.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 DUF605 PF04652.11 OAJ31436.1 - 0.026 13.9 2.0 0.04 13.3 1.4 1.3 1 0 0 1 1 1 0 Vta1 like Ribosomal_S18 PF01084.15 OAJ31436.1 - 0.55 10.1 1.9 7 6.6 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S18 YadA_head PF05658.9 OAJ31436.1 - 0.57 10.5 1.8 1.3 9.4 1.3 1.6 1 0 0 1 1 1 0 Head domain of trimeric autotransporter adhesin GATA PF00320.22 OAJ31437.1 - 3e-12 45.6 5.7 5.7e-12 44.7 3.9 1.5 1 0 0 1 1 1 1 GATA zinc finger FAM163 PF15069.1 OAJ31437.1 - 3.8 8.0 5.5 1.3 9.6 0.0 2.8 2 1 1 3 3 3 0 FAM163 family DUF543 PF04418.7 OAJ31438.1 - 2.7e-28 97.7 0.2 6.8e-28 96.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF543) WT1 PF02165.10 OAJ31438.1 - 0.11 11.5 0.2 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 Wilm's tumour protein DUF883 PF05957.8 OAJ31438.1 - 0.11 12.8 4.4 1.2 9.5 0.2 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) ArgK PF03308.11 OAJ31439.1 - 3.6e-06 25.9 0.1 5.6e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 OAJ31439.1 - 7.1e-05 23.6 0.0 0.0002 22.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 OAJ31439.1 - 0.00012 22.1 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 OAJ31439.1 - 0.00022 20.9 0.0 0.00054 19.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 OAJ31439.1 - 0.00024 20.9 0.0 0.00043 20.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase MobB PF03205.9 OAJ31439.1 - 0.00054 19.6 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 OAJ31439.1 - 0.0013 17.9 0.0 0.0024 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 OAJ31439.1 - 0.0031 17.8 0.0 0.0079 16.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.10 OAJ31439.1 - 0.0035 17.0 0.1 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 NTPase RNA_helicase PF00910.17 OAJ31439.1 - 0.0038 17.3 0.0 0.0078 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase KAP_NTPase PF07693.9 OAJ31439.1 - 0.004 16.1 0.0 0.004 16.1 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_14 PF13173.1 OAJ31439.1 - 0.0053 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 OAJ31439.1 - 0.0093 14.9 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NB-ARC PF00931.17 OAJ31439.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 OAJ31439.1 - 0.039 14.2 0.0 0.08 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_35 PF14516.1 OAJ31439.1 - 0.042 12.4 0.0 0.065 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 OAJ31439.1 - 0.048 13.5 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 OAJ31439.1 - 0.063 13.4 0.1 0.26 11.4 0.0 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ31439.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-RING_2 PF13639.1 OAJ31440.1 - 1.8e-07 30.8 4.6 1.8e-07 30.8 3.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAJ31440.1 - 0.00011 21.8 1.7 0.00011 21.8 1.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 OAJ31440.1 - 0.00014 21.9 10.5 0.00096 19.2 7.3 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 OAJ31440.1 - 0.00042 20.2 2.0 0.0011 18.9 1.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ31440.1 - 0.0012 18.4 2.8 0.0012 18.4 2.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ31440.1 - 0.0056 16.3 2.9 0.0056 16.3 2.0 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 OAJ31440.1 - 0.016 15.0 1.0 0.041 13.7 0.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 OAJ31440.1 - 0.074 12.8 0.7 0.18 11.6 0.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Pyridox_oxidase PF01243.15 OAJ31441.1 - 0.0093 15.9 0.0 0.9 9.5 0.0 3.1 3 0 0 3 3 3 1 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 OAJ31441.1 - 0.028 14.5 0.0 0.26 11.4 0.0 2.5 2 1 0 2 2 2 0 Oxidoreductase FAD-binding domain TP_methylase PF00590.15 OAJ31441.1 - 0.065 12.9 0.2 5.6 6.6 0.0 2.8 3 0 0 3 3 3 0 Tetrapyrrole (Corrin/Porphyrin) Methylases MIF4G PF02854.14 OAJ31442.1 - 0.095 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 MIF4G domain OTU PF02338.14 OAJ31443.1 - 9.2e-21 74.6 0.0 2.4e-20 73.3 0.0 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 OAJ31443.1 - 0.0027 17.1 0.0 0.6 9.4 0.0 2.3 2 0 0 2 2 2 2 Peptidase C65 Otubain DUF3618 PF12277.3 OAJ31443.1 - 5.3 7.1 10.0 5.6 7.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) DPBB_1 PF03330.13 OAJ31444.1 - 1.1e-11 44.5 0.1 2.1e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Glyco_hydro_cc PF11790.3 OAJ31446.1 - 3.1e-40 138.0 0.1 4.3e-40 137.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core SOG2 PF10428.4 OAJ31446.1 - 0.04 12.5 0.4 0.05 12.2 0.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Zip PF02535.17 OAJ31446.1 - 0.062 12.2 17.5 0.1 11.5 12.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Epimerase PF01370.16 OAJ31447.1 - 4.9e-06 26.1 0.0 0.1 12.0 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 OAJ31447.1 - 0.0011 19.2 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 OAJ31447.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Glyco_tran_WecB PF03808.8 OAJ31447.1 - 0.044 13.1 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family adh_short PF00106.20 OAJ31447.1 - 0.045 13.6 0.4 0.17 11.7 0.0 2.0 2 1 0 2 2 2 0 short chain dehydrogenase KR PF08659.5 OAJ31447.1 - 0.11 12.1 0.5 0.32 10.6 0.4 1.8 1 1 0 1 1 1 0 KR domain Zn_clus PF00172.13 OAJ31449.1 - 3.8e-07 29.8 8.6 8.1e-07 28.8 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGAP PF00620.22 OAJ31451.1 - 2.3e-35 121.4 0.0 3.6e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain HTH_Tnp_Tc5 PF03221.11 OAJ31453.1 - 1.9e-06 27.5 0.1 3.5e-05 23.5 0.0 2.3 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain HTH_26 PF13443.1 OAJ31453.1 - 0.038 14.1 0.1 0.98 9.6 0.0 2.5 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Pro_CA PF00484.14 OAJ31455.1 - 2.5e-35 121.7 0.1 4.4e-35 120.9 0.1 1.4 1 0 0 1 1 1 1 Carbonic anhydrase SWM_repeat PF13753.1 OAJ31455.1 - 0.0061 15.6 0.2 0.012 14.7 0.1 1.5 1 0 0 1 1 1 1 Putative flagellar system-associated repeat Phospholip_A2_2 PF05826.7 OAJ31455.1 - 0.083 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Phospholipase A2 AAA_12 PF13087.1 OAJ31456.1 - 7.7e-32 110.2 0.0 1.3e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAJ31456.1 - 5.7e-29 101.3 0.0 4.3e-28 98.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ31456.1 - 3.2e-09 36.4 0.5 9.6e-09 34.8 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 OAJ31456.1 - 5.2e-08 32.7 0.1 0.0012 18.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 OAJ31456.1 - 0.00039 19.4 0.0 0.0019 17.2 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 OAJ31456.1 - 0.01 15.1 0.0 0.77 8.9 0.0 2.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain ResIII PF04851.10 OAJ31456.1 - 0.033 14.0 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.1 OAJ31456.1 - 0.043 13.9 0.0 0.16 12.1 0.0 2.0 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD_C PF13361.1 OAJ31456.1 - 0.052 12.9 0.1 0.27 10.6 0.1 2.0 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain ADH_N PF08240.7 OAJ31458.1 - 9.8e-29 99.3 2.1 2.6e-28 97.9 1.4 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ31458.1 - 3.5e-22 78.3 0.2 5.8e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PQQ PF01011.16 OAJ31458.1 - 0.0024 17.3 0.1 0.0053 16.2 0.0 1.6 1 0 0 1 1 1 1 PQQ enzyme repeat Myb_DNA-bind_3 PF12776.2 OAJ31460.1 - 0.00035 21.1 0.5 0.0028 18.2 0.0 2.5 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain PAPS_reduct PF01507.14 OAJ31462.1 - 1.2e-36 126.1 0.0 1.6e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Pkinase PF00069.20 OAJ31464.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain VPS28 PF03997.7 OAJ31465.1 - 7.7e-44 149.5 0.0 1.5e-43 148.6 0.0 1.5 1 1 0 1 1 1 1 VPS28 protein DUF469 PF04320.9 OAJ31465.1 - 0.047 14.4 0.0 0.18 12.5 0.0 1.9 2 1 0 2 2 2 0 Protein with unknown function (DUF469) X PF00739.14 OAJ31466.1 - 3.7 7.4 5.6 7 6.5 3.9 1.5 1 0 0 1 1 1 0 Trans-activation protein X ECF-ribofla_trS PF07155.7 OAJ31467.1 - 0.038 13.7 1.7 0.093 12.4 1.1 1.6 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component PrgI PF12666.2 OAJ31467.1 - 0.27 11.4 1.8 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 PrgI family protein Pkinase PF00069.20 OAJ31468.1 - 1e-40 139.5 0.0 1.1e-27 96.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ31468.1 - 1.2e-23 83.4 0.0 1.8e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ31468.1 - 0.038 12.9 0.0 0.091 11.6 0.0 1.6 1 0 0 1 1 1 0 Kinase-like TPR_12 PF13424.1 OAJ31469.1 - 0.00046 20.0 0.9 0.0023 17.8 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ31469.1 - 0.0073 16.1 0.1 11 6.2 0.0 3.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ31469.1 - 0.036 14.2 0.4 0.14 12.2 0.3 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 F1F0-ATPsyn_F PF10791.4 OAJ31470.1 - 1.9e-31 108.1 0.1 2.3e-31 107.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Hexapep PF00132.19 OAJ31471.1 - 1.5e-11 43.2 4.3 1.7e-05 24.1 0.6 3.5 2 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 OAJ31471.1 - 2.6e-06 26.8 3.5 0.12 11.9 0.0 3.3 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 OAJ31471.1 - 0.044 12.3 0.0 0.058 11.9 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase Polysacc_synt_4 PF04669.8 OAJ31472.1 - 3.6e-25 88.4 4.0 2e-24 86.0 2.8 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis RRP14 PF15459.1 OAJ31472.1 - 0.18 11.8 3.2 0.51 10.4 2.2 1.9 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 NDUF_B12 PF08122.7 OAJ31473.1 - 5.4e-18 64.4 0.2 9.5e-18 63.6 0.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Transp_cyt_pur PF02133.10 OAJ31474.1 - 6.5e-129 430.3 42.5 1.7e-121 405.8 23.4 2.0 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin adh_short PF00106.20 OAJ31475.1 - 2.1e-23 83.0 0.6 3.4e-23 82.4 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ31475.1 - 5.4e-13 49.2 0.2 7e-13 48.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ31475.1 - 1.4e-05 24.8 0.2 4.3e-05 23.2 0.1 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAJ31475.1 - 1.9e-05 24.1 0.5 5.2e-05 22.7 0.1 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ31475.1 - 0.00035 20.6 0.5 0.00066 19.7 0.3 1.5 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 OAJ31475.1 - 0.0099 15.6 0.2 1.3 8.8 0.0 2.9 3 0 0 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peroxidase_2 PF01328.12 OAJ31476.1 - 3.5e-15 55.4 0.3 8.7e-15 54.1 0.2 1.5 1 1 0 1 1 1 1 Peroxidase, family 2 G-patch_2 PF12656.2 OAJ31477.1 - 4.4e-25 87.3 0.3 4.4e-25 87.3 0.2 2.9 3 1 1 4 4 4 1 DExH-box splicing factor binding site G-patch PF01585.18 OAJ31477.1 - 3.5e-06 26.6 3.2 6.7e-06 25.7 2.2 1.5 1 0 0 1 1 1 1 G-patch domain Redoxin PF08534.5 OAJ31478.1 - 5e-29 100.7 0.1 5.7e-29 100.5 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAJ31478.1 - 5.4e-12 45.4 0.0 7.1e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Glycos_transf_2 PF00535.21 OAJ31479.1 - 5.5e-29 101.0 0.0 7.1e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 OAJ31479.1 - 9.2e-13 48.5 0.0 1.8e-12 47.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 OAJ31479.1 - 5.1e-06 25.7 0.0 7e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 OAJ31479.1 - 0.0011 18.3 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_7N PF13733.1 OAJ31479.1 - 0.007 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_trans_2_3 PF13632.1 OAJ31479.1 - 0.02 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.1 OAJ31479.1 - 0.044 14.1 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 HCNGP PF07818.8 OAJ31480.1 - 7.9e-18 64.2 0.0 1.5e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 HCNGP-like protein PRP38_assoc PF12871.2 OAJ31480.1 - 0.0028 18.1 23.9 0.0028 18.1 16.6 2.4 2 0 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Paramyxo_ncap PF00973.14 OAJ31480.1 - 0.13 10.9 9.0 0.21 10.2 6.2 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Apt1 PF10351.4 OAJ31480.1 - 0.19 10.5 5.4 0.3 9.9 3.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM220 PF15487.1 OAJ31480.1 - 2 7.6 14.7 0.052 12.9 4.5 2.3 2 0 0 2 2 2 0 FAM220 family Cwf_Cwc_15 PF04889.7 OAJ31482.1 - 0.045 13.4 21.2 0.079 12.6 14.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.7 OAJ31482.1 - 0.71 8.1 23.5 1 7.6 16.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) eIF-3c_N PF05470.7 OAJ31482.1 - 1.5 6.8 14.1 1.9 6.4 9.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus TFIIA PF03153.8 OAJ31482.1 - 1.8 8.3 21.7 2.2 8.0 15.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 OAJ31482.1 - 3 5.6 23.2 3.5 5.4 16.1 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 OAJ31482.1 - 3.4 6.0 18.4 4.1 5.7 12.7 1.1 1 0 0 1 1 1 0 Daxx Family K_channel_TID PF07941.6 OAJ31483.1 - 0.059 13.6 5.2 0.08 13.1 3.6 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain rve PF00665.21 OAJ31486.1 - 8.7e-17 61.3 0.0 7e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Med13_C PF06333.7 OAJ31488.1 - 5.8e-07 28.3 0.0 1.8e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal RNA_pol_L_2 PF13656.1 OAJ31489.1 - 1.1e-27 95.2 0.0 1.6e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 OAJ31489.1 - 1.2e-08 33.9 0.0 1.8e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain mit_SMPDase PF14724.1 OAJ31489.1 - 0.03 12.1 0.0 0.036 11.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase zf-C2H2 PF00096.21 OAJ31489.1 - 0.073 13.4 0.5 0.13 12.6 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type PEP-utilisers_N PF05524.8 OAJ31489.1 - 0.15 11.8 2.3 0.53 10.1 0.1 2.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Lyase_1 PF00206.15 OAJ31490.1 - 7.2e-22 77.9 0.0 1.1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 OAJ31490.1 - 3.6e-16 58.9 0.0 8.2e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus M20_dimer PF07687.9 OAJ31491.1 - 5.6e-09 35.7 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 OAJ31491.1 - 3.8e-08 33.0 0.2 5.6e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 NKWYS PF10364.4 OAJ31491.1 - 0.044 13.5 0.3 0.076 12.7 0.2 1.3 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein SR-25 PF10500.4 OAJ31492.1 - 0.017 14.6 7.9 0.02 14.3 5.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 OAJ31492.1 - 0.58 10.2 7.7 0.8 9.7 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Med3 PF11593.3 OAJ31492.1 - 2.9 7.0 13.1 3.3 6.8 9.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CH PF00307.26 OAJ31493.1 - 2.4e-40 136.9 0.2 6.2e-22 77.6 0.1 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 OAJ31493.1 - 3.1e-18 65.5 0.0 8.8e-18 64.0 0.0 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 OAJ31493.1 - 1e-13 50.6 0.1 9.3e-10 38.0 0.1 2.5 2 0 0 2 2 2 2 CAMSAP CH domain Tektin PF03148.9 OAJ31493.1 - 0.0007 18.2 0.5 0.0012 17.4 0.3 1.3 1 0 0 1 1 1 1 Tektin family EF-hand_6 PF13405.1 OAJ31493.1 - 0.089 12.7 0.0 1.2 9.1 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain Spectrin PF00435.16 OAJ31493.1 - 0.24 11.6 4.7 1.4 9.1 0.3 3.1 2 1 0 2 2 2 0 Spectrin repeat Baculo_PEP_C PF04513.7 OAJ31493.1 - 0.6 9.9 3.7 0.35 10.7 0.2 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cse1 PF08506.5 OAJ31494.1 - 1.1e-19 70.2 0.0 1.5e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 OAJ31494.1 - 3.8e-10 39.5 0.6 4.3e-06 26.5 0.0 2.8 2 1 1 3 3 3 2 Importin-beta N-terminal domain Xpo1 PF08389.7 OAJ31494.1 - 0.033 14.1 0.1 0.095 12.6 0.0 1.9 1 1 0 1 1 1 0 Exportin 1-like protein HEAT_EZ PF13513.1 OAJ31494.1 - 0.11 13.0 6.9 2.1 8.9 1.4 3.4 3 0 0 3 3 3 0 HEAT-like repeat DASH_Spc34 PF08657.5 OAJ31495.1 - 2.4e-08 34.0 0.4 1.3e-05 25.0 0.1 2.4 1 1 0 2 2 2 2 DASH complex subunit Spc34 DivIC PF04977.10 OAJ31495.1 - 3.6 7.1 9.9 13 5.4 0.4 3.2 3 0 0 3 3 3 0 Septum formation initiator NUC153 PF08159.7 OAJ31496.1 - 6.2e-11 41.6 0.2 1.1e-10 40.9 0.2 1.4 1 0 0 1 1 1 1 NUC153 domain Nop14 PF04147.7 OAJ31496.1 - 0.066 11.1 20.7 0.094 10.6 14.4 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpb4 PF03874.11 OAJ31497.1 - 4.6e-14 52.4 0.1 6.8e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Cep57_CLD_2 PF14197.1 OAJ31497.1 - 1.4 8.9 4.5 8.2 6.4 1.8 2.6 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 NAD_binding_5 PF07994.7 OAJ31498.1 - 4.9e-108 361.1 0.0 6.4e-108 360.7 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 OAJ31498.1 - 2.1e-42 143.4 0.1 3.6e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Peptidase_M17 PF00883.16 OAJ31499.1 - 1.3e-110 369.1 0.1 1.8e-110 368.6 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 OAJ31499.1 - 1.8e-07 30.9 0.0 4.4e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Pmp3 PF01679.12 OAJ31500.1 - 4.5e-20 71.0 5.2 7.7e-20 70.3 3.6 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator APS_kinase PF01583.15 OAJ31501.1 - 1.5e-70 235.8 0.0 1.9e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 OAJ31501.1 - 1.4e-07 31.4 0.0 2e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ31501.1 - 4.9e-06 27.3 0.0 8.4e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ31501.1 - 4.1e-05 23.8 0.0 0.00011 22.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 OAJ31501.1 - 0.00061 19.0 0.0 0.00096 18.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 OAJ31501.1 - 0.0027 17.2 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Thymidylate_kin PF02223.12 OAJ31501.1 - 0.054 12.8 0.0 5.6 6.2 0.0 2.3 1 1 1 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.7 OAJ31501.1 - 0.056 12.5 0.0 0.28 10.2 0.0 1.9 1 1 0 2 2 2 0 Zeta toxin Arf PF00025.16 OAJ31501.1 - 0.058 12.6 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_16 PF13191.1 OAJ31501.1 - 0.096 12.6 0.1 0.21 11.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 OAJ31501.1 - 0.11 12.2 0.0 0.22 11.1 0.0 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 OAJ31501.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family WD40 PF00400.27 OAJ31502.1 - 6.8e-14 51.1 4.4 4.3e-08 32.7 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Ribosomal_L1 PF00687.16 OAJ31503.1 - 1.9e-49 167.9 1.2 2.2e-49 167.7 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Borealin PF10512.4 OAJ31503.1 - 0.14 12.0 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 Adaptin_binding PF10199.4 OAJ31504.1 - 0.14 12.4 26.2 0.058 13.6 11.2 3.8 3 1 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 Fungal_trans PF04082.13 OAJ31505.1 - 1.3e-15 56.9 0.0 1.9e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ31505.1 - 2e-06 27.5 9.7 3.5e-06 26.8 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0020 PF01170.13 OAJ31506.1 - 8.1e-14 51.5 0.0 2.8e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 OAJ31506.1 - 1.3e-12 47.7 0.1 7.9e-12 45.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ31506.1 - 0.0021 17.6 0.0 0.052 13.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ31506.1 - 0.009 16.4 0.0 0.024 15.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ31506.1 - 0.021 15.1 0.0 0.069 13.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ31506.1 - 0.13 11.3 0.0 0.87 8.6 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family zf-CCCH PF00642.19 OAJ31507.1 - 0.00063 19.3 1.9 0.0011 18.5 1.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleoporin_FG PF13634.1 OAJ31507.1 - 0.013 15.7 40.6 0.013 15.7 28.2 6.2 1 1 2 3 3 3 0 Nucleoporin FG repeat region zf-CCCH_2 PF14608.1 OAJ31507.1 - 0.38 10.8 3.2 1.1 9.3 2.2 1.9 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Ribosomal_L10 PF00466.15 OAJ31508.1 - 5.2e-16 58.4 0.0 7.6e-15 54.6 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L10 DUF2457 PF10446.4 OAJ31508.1 - 0.022 13.4 4.5 0.033 12.9 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 OAJ31508.1 - 0.2 11.9 9.1 0.38 11.0 6.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 OAJ31508.1 - 0.29 10.6 5.7 0.52 9.8 4.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 OAJ31508.1 - 0.36 10.0 2.6 0.5 9.5 1.8 1.2 1 0 0 1 1 1 0 NOA36 protein JAB PF01398.16 OAJ31510.1 - 1e-26 92.9 0.1 1.6e-26 92.2 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 OAJ31510.1 - 2.4e-06 27.0 0.0 4.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 OAJ31510.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) TFIIF_alpha PF05793.7 OAJ31510.1 - 1.2 7.4 7.3 1.6 6.9 5.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2360 PF10152.4 OAJ31510.1 - 7.9 6.7 7.7 8.1 6.7 2.1 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) SIN1 PF05422.7 OAJ31511.1 - 2.6e-24 85.6 0.0 2.6e-13 49.3 0.0 2.6 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) MttA_Hcf106 PF02416.11 OAJ31512.1 - 0.097 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 mttA/Hcf106 family Abhydrolase_6 PF12697.2 OAJ31513.1 - 1e-22 81.1 1.7 2.1e-22 80.1 1.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ31513.1 - 2.3e-08 33.9 0.0 5.7e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ31513.1 - 1e-06 28.4 0.0 0.018 14.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAJ31513.1 - 0.00055 19.7 0.5 0.0011 18.7 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase DUF676 PF05057.9 OAJ31513.1 - 0.044 13.0 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) His_biosynth PF00977.16 OAJ31514.1 - 1.1e-39 136.1 0.0 7.5e-24 84.2 0.0 2.9 2 1 0 2 2 2 2 Histidine biosynthesis protein GATase PF00117.23 OAJ31514.1 - 3.9e-22 78.6 0.0 7e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 OAJ31514.1 - 8.9e-09 35.1 0.1 2.6e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 OAJ31514.1 - 9.1e-07 28.6 0.0 4.6e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 OAJ31514.1 - 0.074 12.4 0.3 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 Asp PF00026.18 OAJ31516.1 - 2e-60 204.6 1.2 2.5e-60 204.3 0.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ31516.1 - 1.1e-07 31.9 0.2 2e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 OAJ31516.1 - 0.06 12.8 0.0 0.25 10.8 0.0 2.0 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal MFS_1 PF07690.11 OAJ31517.1 - 2.8e-18 65.7 10.9 2.8e-18 65.7 7.6 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.23 OAJ31518.1 - 2.9e-78 263.1 0.0 4.6e-78 262.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 OAJ31518.1 - 3.6e-65 219.3 0.0 5.7e-65 218.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 OAJ31518.1 - 2.3e-13 50.2 0.0 5.7e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 OAJ31518.1 - 2.8e-09 37.7 0.0 9e-09 36.1 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 OAJ31518.1 - 1.3e-07 31.2 0.0 2.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAJ31518.1 - 0.004 15.8 0.0 0.18 10.4 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.15 OAJ31518.1 - 0.0054 15.6 0.1 0.076 11.8 0.0 2.2 2 0 0 2 2 2 1 Condensation domain Polysacc_synt_2 PF02719.10 OAJ31518.1 - 0.013 14.4 0.0 0.038 12.8 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PTPlike_phytase PF14566.1 OAJ31519.1 - 0.00013 22.0 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 OAJ31519.1 - 0.00022 20.8 0.0 0.00044 19.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 OAJ31519.1 - 0.00061 20.0 0.5 0.0031 17.7 0.0 2.3 2 1 1 3 3 3 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 OAJ31519.1 - 0.021 14.1 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase EF-hand_1 PF00036.27 OAJ31520.1 - 4.2e-28 94.4 12.7 2.7e-08 32.5 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 OAJ31520.1 - 3.4e-25 87.9 10.9 6.3e-13 48.6 3.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 OAJ31520.1 - 4.4e-24 82.1 9.6 1.9e-07 30.3 0.0 4.3 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 OAJ31520.1 - 1.5e-20 72.5 12.3 6.2e-09 35.3 1.8 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 OAJ31520.1 - 7e-16 56.7 11.6 0.00016 20.8 1.0 4.2 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 OAJ31520.1 - 2.9e-12 46.3 0.3 2.5e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 OAJ31520.1 - 1.9e-06 27.5 1.9 0.034 13.8 0.4 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 OAJ31520.1 - 0.025 14.1 0.2 0.28 10.7 0.0 2.3 2 1 1 3 3 3 0 Caleosin related protein SPARC_Ca_bdg PF10591.4 OAJ31520.1 - 0.035 14.1 1.3 7.5 6.6 0.2 2.2 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DHHA1 PF02272.14 OAJ31520.1 - 0.26 10.9 4.8 0.67 9.7 1.1 2.5 2 1 0 2 2 2 0 DHHA1 domain MgtE_N PF03448.12 OAJ31520.1 - 0.33 11.2 3.2 0.45 10.8 0.9 2.0 2 0 0 2 2 2 0 MgtE intracellular N domain Toprim_2 PF13155.1 OAJ31520.1 - 0.36 11.1 2.2 15 6.0 0.1 2.4 1 1 1 2 2 2 0 Toprim-like SHOCT PF09851.4 OAJ31520.1 - 0.79 9.2 3.9 0.6 9.6 0.4 2.6 2 0 0 2 2 2 0 Short C-terminal domain UQ_con PF00179.21 OAJ31521.1 - 8.7e-21 73.8 0.0 1.2e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Kei1 PF08552.6 OAJ31522.1 - 5.4e-45 153.3 1.4 6.7e-45 153.0 0.9 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 ICE2 PF08426.5 OAJ31523.1 - 1.4e-40 139.1 0.0 2.8e-37 128.2 0.0 3.3 1 1 0 1 1 1 1 ICE2 ATP-synt_ab PF00006.20 OAJ31524.1 - 1.3e-69 233.9 0.0 2.2e-69 233.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 OAJ31524.1 - 4.1e-23 81.9 0.0 1.4e-22 80.3 0.0 2.0 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 OAJ31524.1 - 4e-18 65.3 1.8 1e-17 64.0 1.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 OAJ31524.1 - 0.00028 20.7 0.5 0.00089 19.1 0.4 1.9 1 1 0 1 1 1 1 HAS barrel domain Sec62 PF03839.11 OAJ31525.1 - 1.1e-44 152.5 6.3 3.5e-44 150.8 4.4 1.7 1 1 0 1 1 1 1 Translocation protein Sec62 RNA_pol_I_TF PF04090.7 OAJ31526.1 - 7.5e-06 25.3 0.0 6.8e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor DUF92 PF01940.11 OAJ31527.1 - 1.4e-32 112.6 3.3 2e-32 112.1 2.3 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 Nol1_Nop2_Fmu PF01189.12 OAJ31529.1 - 3.7e-27 95.4 0.0 3.6e-17 62.6 0.0 3.9 3 1 1 4 4 4 4 NOL1/NOP2/sun family FtsJ PF01728.14 OAJ31529.1 - 0.087 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Daxx PF03344.10 OAJ31530.1 - 0.025 13.0 14.8 0.036 12.5 10.3 1.3 1 0 0 1 1 1 0 Daxx Family Carb_kinase PF01256.12 OAJ31531.1 - 6e-54 182.8 0.0 7.7e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 OAJ31531.1 - 0.00029 20.1 0.0 0.0015 17.7 0.0 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DUF4516 PF14990.1 OAJ31531.1 - 0.3 10.6 1.6 0.45 10.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) COG6 PF06419.6 OAJ31532.1 - 7e-105 351.4 0.0 4.2e-88 296.0 0.0 2.8 2 1 0 2 2 2 2 Conserved oligomeric complex COG6 Exo70 PF03081.10 OAJ31532.1 - 0.049 12.4 0.0 0.15 10.8 0.0 1.8 1 0 0 1 1 1 0 Exo70 exocyst complex subunit p450 PF00067.17 OAJ31533.1 - 2.6e-40 138.3 0.0 5.6e-40 137.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 OAJ31534.1 - 5.1e-13 48.8 0.0 5.8e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 OAJ31534.1 - 8.5e-05 22.5 0.1 0.00025 21.0 0.0 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAJ31534.1 - 0.0024 17.8 0.0 0.0026 17.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 OAJ31534.1 - 0.0071 16.7 0.0 0.0095 16.3 0.0 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 OAJ31534.1 - 0.0097 14.8 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 OAJ31534.1 - 0.014 15.4 0.0 0.018 15.1 0.0 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 OAJ31534.1 - 0.016 14.2 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain GDI PF00996.13 OAJ31534.1 - 0.018 13.3 0.0 0.021 13.1 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor FAD_binding_2 PF00890.19 OAJ31534.1 - 0.019 13.8 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 OAJ31534.1 - 0.022 14.2 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 OAJ31534.1 - 0.028 14.4 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 OAJ31534.1 - 0.037 12.5 0.0 0.045 12.2 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 OAJ31534.1 - 0.053 13.2 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 OAJ31534.1 - 0.064 12.1 0.0 0.081 11.8 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein ThiF PF00899.16 OAJ31534.1 - 0.086 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 ThiF family GIDA PF01134.17 OAJ31534.1 - 0.15 10.9 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A GMC_oxred_C PF05199.8 OAJ31535.1 - 1e-28 100.4 0.2 1.5e-28 99.8 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 OAJ31535.1 - 4e-20 72.1 0.0 6.2e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase RNA_pol_Rpc4 PF05132.9 OAJ31538.1 - 9.1e-19 67.7 0.0 9.1e-19 67.7 0.0 4.3 5 0 0 5 5 5 2 RNA polymerase III RPC4 Leo1 PF04004.8 OAJ31538.1 - 0.081 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Leo1-like protein ABC_tran PF00005.22 OAJ31539.1 - 6.1e-33 114.0 0.0 1.3e-32 112.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 OAJ31539.1 - 3.4e-25 89.0 4.4 7.6e-25 87.8 3.0 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 OAJ31539.1 - 6e-06 26.4 0.0 0.00053 20.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ31539.1 - 0.00025 21.0 0.2 0.00084 19.3 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 OAJ31539.1 - 0.00048 19.3 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 OAJ31539.1 - 0.0026 17.8 0.1 0.0099 16.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAJ31539.1 - 0.021 13.9 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Acyl_transf_3 PF01757.17 OAJ31540.1 - 5.2e-17 61.6 44.1 1.6e-16 60.0 30.5 1.8 1 1 0 1 1 1 1 Acyltransferase family Metal_resist PF13801.1 OAJ31541.1 - 0.0073 16.3 5.2 0.01 15.8 1.2 2.3 2 0 0 2 2 2 1 Heavy-metal resistance OEP PF02321.13 OAJ31541.1 - 0.057 13.0 0.2 0.057 13.0 0.1 2.0 2 0 0 2 2 2 0 Outer membrane efflux protein PRP38 PF03371.10 OAJ31542.1 - 1.2e-61 207.2 0.1 1.6e-61 206.9 0.1 1.1 1 0 0 1 1 1 1 PRP38 family FMO-like PF00743.14 OAJ31543.1 - 3.8e-18 64.9 0.0 1.8e-13 49.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 OAJ31543.1 - 6.7e-13 49.1 0.0 9.1e-12 45.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ31543.1 - 1.1e-05 25.3 1.9 0.00011 22.0 0.1 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAJ31543.1 - 0.00033 20.6 0.0 0.00083 19.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAJ31543.1 - 0.00083 18.3 0.0 0.025 13.4 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 OAJ31543.1 - 0.03 14.4 0.0 5.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF2244 PF10003.4 OAJ31543.1 - 0.12 11.7 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Y_phosphatase PF00102.22 OAJ31544.1 - 7.3e-53 179.3 0.0 8.3e-46 156.2 0.0 2.8 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 OAJ31544.1 - 5.2e-05 23.5 0.0 0.00036 20.8 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 OAJ31544.1 - 0.0094 16.2 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 OAJ31544.1 - 0.013 15.0 0.1 0.027 14.0 0.1 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Dicty_REP PF05086.7 OAJ31544.1 - 0.25 9.0 2.2 0.48 8.1 1.6 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Asp PF00026.18 OAJ31545.1 - 3e-48 164.7 0.2 9.7e-48 163.0 0.1 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 OAJ31545.1 - 4.2e-06 27.1 1.2 0.012 16.0 0.1 2.7 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 OAJ31545.1 - 0.091 12.3 0.0 0.22 11.0 0.0 1.7 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Arv1 PF04161.8 OAJ31546.1 - 1.3e-20 74.2 0.8 5.6e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 Arv1-like family eIF-5_eIF-2B PF01873.12 OAJ31546.1 - 1.7 8.3 3.0 0.76 9.4 0.6 1.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 ABM PF03992.11 OAJ31547.1 - 9.2e-08 32.0 0.1 1.1e-07 31.7 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase APC_CDC26 PF10471.4 OAJ31548.1 - 0.15 12.8 4.1 0.22 12.2 2.8 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 HpcH_HpaI PF03328.9 OAJ31549.1 - 2.4e-36 124.7 0.1 9.2e-36 122.7 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 OAJ31549.1 - 1.6e-08 33.7 0.0 0.0006 18.7 0.0 2.5 2 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Anoctamin PF04547.7 OAJ31550.1 - 4.8e-96 322.1 0.0 6e-96 321.8 0.0 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel BAG PF02179.11 OAJ31551.1 - 9.7e-13 48.0 0.2 1.1e-11 44.6 0.1 2.2 2 0 0 2 2 2 1 BAG domain ubiquitin PF00240.18 OAJ31551.1 - 4.1e-08 32.5 0.0 7.2e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 OAJ31551.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain TarH PF02203.10 OAJ31551.1 - 0.067 13.0 4.8 0.1 12.3 3.3 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue DUF3824 PF12868.2 OAJ31551.1 - 0.82 10.6 9.5 0.061 14.2 3.0 1.7 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Thioredoxin_8 PF13905.1 OAJ31552.1 - 2.7e-10 40.2 0.1 1.1e-09 38.2 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 OAJ31552.1 - 0.00073 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAJ31552.1 - 0.01 15.5 0.0 0.036 13.7 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Glu_synthase PF01645.12 OAJ31553.1 - 6.6e-160 532.0 0.1 1.9e-159 530.4 0.0 1.8 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 OAJ31553.1 - 3.1e-139 463.6 0.0 4.3e-139 463.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 OAJ31553.1 - 4.6e-116 387.1 0.0 7.5e-116 386.4 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 OAJ31553.1 - 2.6e-68 228.9 1.6 2.6e-68 228.9 1.1 2.0 2 0 0 2 2 2 1 GXGXG motif Fer4_20 PF14691.1 OAJ31553.1 - 4.2e-23 81.0 0.1 1.2e-22 79.6 0.0 1.8 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 OAJ31553.1 - 5e-19 68.9 0.0 3.7e-18 66.1 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAJ31553.1 - 1e-09 38.7 0.3 9.2e-05 22.5 0.1 2.9 2 1 1 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAJ31553.1 - 2.2e-09 37.1 0.0 8.4e-09 35.3 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAJ31553.1 - 7.7e-08 32.6 0.2 0.00014 22.1 0.2 3.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 OAJ31553.1 - 2.3e-07 30.2 0.1 3.6e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 OAJ31553.1 - 4e-05 22.8 0.2 9.8e-05 21.5 0.2 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 OAJ31553.1 - 6.1e-05 22.0 0.3 6.1e-05 22.0 0.2 2.0 2 0 0 2 2 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 OAJ31553.1 - 7.6e-05 21.3 0.1 7.6e-05 21.3 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 OAJ31553.1 - 7.9e-05 22.2 0.0 0.016 14.7 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 OAJ31553.1 - 0.00023 20.3 0.2 0.00023 20.3 0.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 OAJ31553.1 - 0.0004 19.3 3.1 0.00047 19.1 0.2 2.6 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.14 OAJ31553.1 - 0.00057 19.0 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FMN_dh PF01070.13 OAJ31553.1 - 0.003 16.4 1.4 0.079 11.7 0.8 2.8 3 0 0 3 3 3 1 FMN-dependent dehydrogenase NAD_binding_7 PF13241.1 OAJ31553.1 - 0.006 16.8 0.8 0.44 10.8 0.0 3.1 2 0 0 2 2 2 1 Putative NAD(P)-binding DJ-1_PfpI PF01965.19 OAJ31553.1 - 0.0061 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family GIDA PF01134.17 OAJ31553.1 - 0.008 15.0 0.6 0.05 12.4 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 OAJ31553.1 - 0.013 14.7 0.1 0.071 12.2 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 OAJ31553.1 - 0.016 14.9 0.1 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GATase_6 PF13522.1 OAJ31553.1 - 0.029 14.3 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain Lycopene_cycl PF05834.7 OAJ31553.1 - 0.049 12.5 0.2 4.8 5.9 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 OAJ31553.1 - 0.056 13.2 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding AdoHcyase_NAD PF00670.16 OAJ31553.1 - 0.19 11.5 3.4 12 5.6 0.0 3.5 4 0 0 4 4 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.15 OAJ31553.1 - 0.26 11.3 1.5 8.9 6.4 0.0 3.1 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 OAJ31553.1 - 0.47 8.5 0.0 1.1 7.3 0.0 1.6 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like DUF917 PF06032.7 OAJ31554.1 - 0.2 10.1 0.0 0.29 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) SAC3_GANP PF03399.11 OAJ31555.1 - 5.6e-69 231.7 1.5 7.6e-69 231.3 1.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 OAJ31555.1 - 0.0035 17.0 0.8 0.0081 15.9 0.1 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 Nha1_C PF08619.5 OAJ31555.1 - 0.024 13.9 0.6 0.033 13.4 0.4 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus YEATS PF03366.11 OAJ31556.1 - 5.9e-31 106.0 0.0 1.2e-30 105.0 0.0 1.5 1 1 0 1 1 1 1 YEATS family NTR2 PF15458.1 OAJ31556.1 - 0.0059 15.8 1.5 0.0086 15.3 1.0 1.2 1 0 0 1 1 1 1 Nineteen complex-related protein 2 OPA3 PF07047.7 OAJ31556.1 - 0.027 14.2 0.2 0.046 13.5 0.1 1.4 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) DUF2570 PF10828.3 OAJ31556.1 - 4.1 7.0 5.9 1.2 8.7 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) p47_phox_C PF08944.6 OAJ31557.1 - 0.52 10.5 3.1 3.3 7.9 0.2 2.4 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain Actin PF00022.14 OAJ31558.1 - 8.7e-20 70.4 0.0 7.6e-11 41.0 0.0 3.2 3 0 0 3 3 3 3 Actin DUF3188 PF11384.3 OAJ31559.1 - 0.015 14.8 1.1 0.034 13.7 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) PspB PF06667.7 OAJ31559.1 - 0.042 13.7 0.1 0.091 12.7 0.1 1.5 1 0 0 1 1 1 0 Phage shock protein B PgaD PF13994.1 OAJ31559.1 - 0.053 12.9 0.3 0.11 11.9 0.2 1.4 1 0 0 1 1 1 0 PgaD-like protein Neur_chan_memb PF02932.11 OAJ31559.1 - 1.3 8.8 5.4 0.96 9.2 1.9 2.1 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Kinesin PF00225.18 OAJ31561.1 - 1.3e-92 310.1 4.5 1.7e-92 309.7 0.0 2.7 3 0 0 3 3 3 1 Kinesin motor domain Surfac_D-trimer PF09006.6 OAJ31561.1 - 0.013 15.1 3.0 0.051 13.2 2.1 2.0 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Macoilin PF09726.4 OAJ31561.1 - 0.5 8.5 21.4 0.014 13.6 9.3 2.2 2 0 0 2 2 2 0 Transmembrane protein Filament PF00038.16 OAJ31561.1 - 1.5 8.2 26.4 0.41 10.0 7.5 2.4 1 1 1 2 2 2 0 Intermediate filament protein Peptidase_M43 PF05572.8 OAJ31562.1 - 2.9e-17 62.6 0.1 4.5e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.1 OAJ31562.1 - 0.00013 21.5 0.1 0.00018 21.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 OAJ31562.1 - 0.00067 20.1 0.2 0.002 18.6 0.1 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 OAJ31562.1 - 0.00084 19.0 0.0 0.0015 18.2 0.0 1.4 1 1 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.1 OAJ31562.1 - 0.0049 16.9 0.5 0.0095 16.0 0.2 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAJ31562.1 - 0.0054 16.6 0.1 0.01 15.8 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M7 PF02031.11 OAJ31562.1 - 0.034 13.8 0.1 0.068 12.8 0.1 1.5 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family EAP30 PF04157.11 OAJ31563.1 - 5.8e-28 97.5 1.0 2e-27 95.8 0.7 1.8 1 1 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 OAJ31563.1 - 8e-24 83.2 0.0 1.6e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 OAJ31563.1 - 0.051 13.1 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 GRAM domain zf-RanBP PF00641.13 OAJ31563.1 - 0.22 10.6 1.7 0.42 9.7 1.2 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.1 OAJ31563.1 - 0.25 10.6 0.6 0.45 9.7 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Rubredoxin PF00301.15 OAJ31563.1 - 0.54 10.1 4.1 0.26 11.2 0.7 2.0 1 1 0 1 1 1 0 Rubredoxin HsbA PF12296.3 OAJ31564.1 - 0.005 16.6 3.1 0.005 16.6 2.1 2.1 1 1 1 2 2 2 1 Hydrophobic surface binding protein A Vps51 PF08700.6 OAJ31564.1 - 0.088 12.6 0.5 1.9 8.3 0.1 2.8 1 1 1 2 2 2 0 Vps51/Vps67 LZ_Tnp_IS66 PF13007.2 OAJ31564.1 - 0.2 12.3 7.0 0.35 11.5 4.9 1.4 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain DUF677 PF05055.7 OAJ31564.1 - 4.4 5.8 6.3 1.8 7.1 2.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF677) DUF2782 PF11191.3 OAJ31564.1 - 7.8 6.5 6.8 20 5.1 4.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) Frag1 PF10277.4 OAJ31565.1 - 1.2e-36 126.1 14.5 1.4e-36 125.9 10.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Yip1 PF04893.12 OAJ31565.1 - 0.0041 16.6 4.4 0.0041 16.6 3.1 2.5 1 1 1 2 2 2 1 Yip1 domain Tic20 PF09685.5 OAJ31565.1 - 0.051 13.5 12.2 0.41 10.6 2.7 2.8 1 1 1 2 2 2 0 Tic20-like protein Virul_fac_BrkB PF03631.10 OAJ31565.1 - 0.067 12.5 9.4 0.11 11.8 6.1 1.8 1 1 1 2 2 2 0 Virulence factor BrkB DUF1980 PF09323.5 OAJ31565.1 - 0.19 11.4 7.4 0.074 12.7 2.7 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) E1-E2_ATPase PF00122.15 OAJ31565.1 - 2.9 6.8 6.2 5.1 6.0 3.7 1.7 1 1 0 1 1 1 0 E1-E2 ATPase MgtE PF01769.11 OAJ31565.1 - 8.1 6.7 12.9 12 6.1 0.2 2.8 1 1 2 3 3 3 0 Divalent cation transporter DASH_Dad1 PF08649.5 OAJ31566.1 - 1.1e-19 69.8 0.2 1.4e-19 69.5 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Pinin_SDK_N PF04697.8 OAJ31567.1 - 0.06 13.3 0.1 0.076 13.0 0.0 1.2 1 0 0 1 1 1 0 pinin/SDK conserved region DivIC PF04977.10 OAJ31569.1 - 0.025 14.0 1.8 0.025 14.0 1.2 1.9 2 0 0 2 2 2 0 Septum formation initiator Prefoldin PF02996.12 OAJ31569.1 - 0.029 13.9 2.8 0.043 13.4 0.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF812 PF05667.6 OAJ31569.1 - 0.098 11.1 3.5 0.13 10.7 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) AAA_13 PF13166.1 OAJ31569.1 - 0.23 9.9 1.5 0.23 9.8 0.4 1.3 2 0 0 2 2 2 0 AAA domain DUF4407 PF14362.1 OAJ31569.1 - 0.38 9.6 7.0 0.32 9.9 2.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) BRE1 PF08647.6 OAJ31569.1 - 0.63 10.0 5.4 0.5 10.3 1.6 2.2 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase CCAP PF11105.3 OAJ31571.1 - 0.7 9.6 3.6 2 8.1 0.3 2.1 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a zf-CCCH_2 PF14608.1 OAJ31571.1 - 1.2 9.2 14.4 0.87 9.6 0.6 3.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type PINIT PF14324.1 OAJ31573.1 - 2.8e-22 79.3 0.3 4.3e-22 78.7 0.2 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 OAJ31573.1 - 2.2e-20 71.9 4.3 3.5e-20 71.2 3.0 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 OAJ31573.1 - 1.4e-07 30.8 1.0 2.8e-07 29.9 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 OAJ31573.1 - 0.084 12.4 1.2 0.12 11.8 0.1 1.9 2 0 0 2 2 2 0 SAP domain CS PF04969.11 OAJ31574.1 - 3.6e-20 72.3 0.1 6e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 CS domain Dala_Dala_lig_N PF01820.16 OAJ31574.1 - 0.079 13.2 0.4 0.24 11.7 0.0 1.9 2 1 0 2 2 2 0 D-ala D-ala ligase N-terminus CLU PF13236.1 OAJ31575.1 - 8.9e-67 224.7 0.0 2.2e-66 223.4 0.0 1.7 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.2 OAJ31575.1 - 6.3e-43 146.6 0.0 1.6e-42 145.3 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 OAJ31575.1 - 1e-17 63.7 6.0 9.6e-09 35.0 0.7 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ31575.1 - 8.8e-06 25.2 0.7 7.5e-05 22.3 0.3 2.7 3 0 0 3 3 3 1 TPR repeat CLU_N PF15044.1 OAJ31575.1 - 1.1e-05 25.5 0.3 7.9e-05 22.7 0.0 2.5 2 1 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_1 PF00515.23 OAJ31575.1 - 0.00015 21.1 0.2 0.0053 16.3 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ31575.1 - 0.0015 18.1 1.2 0.13 12.0 0.1 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ31575.1 - 0.002 17.9 18.7 0.013 15.4 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ31575.1 - 0.0056 16.5 1.7 0.77 9.8 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ31575.1 - 0.02 14.6 0.1 0.086 12.6 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ31575.1 - 0.091 13.4 0.1 0.091 13.4 0.1 4.4 3 1 1 4 4 3 0 Tetratricopeptide repeat Pox_Ag35 PF03286.9 OAJ31576.1 - 1.1 8.6 5.7 0.2 11.1 0.8 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SDA1 PF05285.7 OAJ31576.1 - 3.7 6.7 10.0 0.81 8.9 0.6 2.1 2 0 0 2 2 2 0 SDA1 Ribosomal_L4 PF00573.17 OAJ31577.1 - 1e-43 148.9 0.4 1e-43 148.9 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 OAJ31577.1 - 3.5e-28 97.2 1.1 1.1e-27 95.7 0.5 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain CAF-1_p150 PF11600.3 OAJ31578.1 - 0.00058 19.3 0.8 0.00089 18.7 0.6 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal PHD PF00628.24 OAJ31579.1 - 1.2e-10 40.8 8.4 2.3e-10 39.9 5.8 1.5 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.3 OAJ31579.1 - 0.00027 20.4 0.0 0.00027 20.4 0.0 2.4 3 0 0 3 3 3 1 CpG binding protein zinc finger C terminal domain PHD_2 PF13831.1 OAJ31579.1 - 0.11 11.8 2.4 0.19 11.0 1.7 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.1 OAJ31580.1 - 2.2e-31 108.0 7.0 2.2e-31 108.0 4.8 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 OAJ31580.1 - 3.8e-23 81.4 5.5 3.8e-23 81.4 3.8 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 OAJ31580.1 - 3.7e-21 76.0 0.5 3.7e-21 76.0 0.3 4.0 4 1 0 4 4 4 1 Enhancer of polycomb-like Bromodomain PF00439.20 OAJ31580.1 - 2.1e-20 72.4 0.1 4.4e-20 71.4 0.1 1.5 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.1 OAJ31580.1 - 3.3e-13 48.6 2.1 3.3e-13 48.6 1.4 2.6 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.12 OAJ31580.1 - 8.7e-11 41.8 0.1 3.2e-10 40.0 0.0 2.1 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 OAJ31580.1 - 1.2e-08 34.4 8.9 1.2e-08 34.4 6.2 2.7 2 0 0 2 2 2 1 PHD-finger PPP4R2 PF09184.6 OAJ31580.1 - 6.7 6.1 29.3 17 4.8 20.3 1.7 1 0 0 1 1 1 0 PPP4R2 AAA PF00004.24 OAJ31581.1 - 2.5e-47 160.3 0.0 1.9e-41 141.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ31581.1 - 4.9e-07 29.9 0.2 2.6e-05 24.3 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 OAJ31581.1 - 1.3e-05 25.1 0.0 4.4e-05 23.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 OAJ31581.1 - 2.1e-05 24.5 0.0 0.056 13.4 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 OAJ31581.1 - 9e-05 21.9 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 OAJ31581.1 - 0.00013 22.1 0.6 0.0094 16.0 0.1 3.4 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.1 OAJ31581.1 - 0.00077 19.1 0.1 0.0033 17.1 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 OAJ31581.1 - 0.0014 18.3 0.0 0.0062 16.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 OAJ31581.1 - 0.0028 17.0 0.1 0.016 14.5 0.0 2.4 3 0 0 3 3 1 1 AAA domain Sigma54_activat PF00158.21 OAJ31581.1 - 0.0039 16.6 0.0 0.86 9.0 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_33 PF13671.1 OAJ31581.1 - 0.0052 16.6 0.1 0.023 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ31581.1 - 0.0056 17.4 0.0 0.03 15.1 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ31581.1 - 0.015 15.5 0.0 0.049 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 OAJ31581.1 - 0.019 15.2 0.1 0.13 12.6 0.0 2.4 3 0 0 3 3 2 0 ABC transporter AAA_14 PF13173.1 OAJ31581.1 - 0.041 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAJ31581.1 - 0.054 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Bromodomain PF00439.20 OAJ31581.1 - 0.055 13.3 0.2 0.15 11.9 0.1 1.8 2 0 0 2 2 1 0 Bromodomain TIP49 PF06068.8 OAJ31581.1 - 0.067 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 OAJ31581.1 - 0.088 11.9 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.6 OAJ31581.1 - 0.1 12.4 0.1 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Torsin PhoH PF02562.11 OAJ31581.1 - 0.13 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 OAJ31581.1 - 0.18 11.6 0.4 0.79 9.5 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MFS_1 PF07690.11 OAJ31583.1 - 1.2e-31 109.7 28.8 1.2e-31 109.7 20.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily LRRC37AB_C PF14914.1 OAJ31583.1 - 0.061 12.7 0.2 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Vpu PF00558.14 OAJ31583.1 - 0.25 10.9 1.4 10 5.7 0.0 3.0 3 0 0 3 3 3 0 Vpu protein DUF202 PF02656.10 OAJ31583.1 - 4.6 7.5 10.3 29 4.9 0.5 4.4 2 2 2 4 4 4 0 Domain of unknown function (DUF202) Helicase_C PF00271.26 OAJ31584.1 - 4.1e-15 55.4 0.0 8.3e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDC45 PF02724.9 OAJ31584.1 - 0.56 8.1 3.2 0.76 7.7 2.2 1.1 1 0 0 1 1 1 0 CDC45-like protein 4HBT PF03061.17 OAJ31585.1 - 2e-11 43.8 0.0 3.8e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DUF3659 PF12396.3 OAJ31585.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) MaoC_dehydratas PF01575.14 OAJ31585.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain DnaJ PF00226.26 OAJ31586.1 - 6.2e-27 93.1 1.5 9.2e-27 92.5 1.0 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 OAJ31586.1 - 1.9e-09 37.2 0.0 8.9e-06 25.5 0.0 2.9 2 1 0 2 2 2 2 DnaJ C terminal domain AAA_12 PF13087.1 OAJ31587.1 - 1.2e-45 155.3 0.0 1.9e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAJ31587.1 - 8.6e-41 140.0 0.0 2.1e-40 138.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ31587.1 - 1.6e-12 46.9 3.2 5.7e-12 45.2 1.4 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 OAJ31587.1 - 2.7e-08 33.6 2.6 7.8e-07 28.8 0.3 3.0 3 0 0 3 3 3 1 AAA domain UvrD-helicase PF00580.16 OAJ31587.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 OAJ31587.1 - 0.00026 20.5 0.1 4 6.8 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 OAJ31587.1 - 0.086 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 OAJ31587.1 - 0.45 9.4 0.4 1.9 7.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Mur_ligase_M PF08245.7 OAJ31588.1 - 0.0012 18.8 0.0 0.003 17.6 0.0 1.5 1 1 0 1 1 1 1 Mur ligase middle domain OTU PF02338.14 OAJ31589.1 - 1.3e-15 58.0 0.0 2.3e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 OAJ31589.1 - 0.02 14.2 0.0 0.81 8.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase C65 Otubain VHS PF00790.14 OAJ31591.1 - 1.2e-19 70.2 0.2 2.2e-19 69.5 0.1 1.3 1 0 0 1 1 1 1 VHS domain Serglycin PF04360.7 OAJ31591.1 - 4.9 6.8 9.7 0.62 9.7 3.1 2.1 2 0 0 2 2 2 0 Serglycin Vps35 PF03635.12 OAJ31592.1 - 0 1100.5 0.0 0 1100.3 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RRM_1 PF00076.17 OAJ31593.1 - 1.4e-21 75.9 0.0 1.9e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ31593.1 - 4.7e-16 58.5 0.0 6.8e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ31593.1 - 1.1e-13 50.7 0.0 1.8e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Adaptin_N PF01602.15 OAJ31594.1 - 1.9e-146 488.4 7.5 2.4e-146 488.1 5.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 OAJ31594.1 - 1.7e-28 99.6 2.0 1.2e-24 87.0 0.1 3.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 OAJ31594.1 - 1.7e-18 66.6 4.5 1.3e-09 38.1 0.0 5.7 1 1 6 7 7 7 6 HEAT repeats HEAT PF02985.17 OAJ31594.1 - 8.9e-12 44.0 4.1 0.00075 19.3 0.0 6.2 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 OAJ31594.1 - 2.7e-08 34.0 4.5 0.0009 19.6 0.0 7.0 6 3 3 9 9 9 1 HEAT-like repeat CLASP_N PF12348.3 OAJ31594.1 - 0.00022 20.6 0.4 1.2 8.4 0.0 4.0 2 2 2 4 4 4 2 CLASP N terminal Cnd3 PF12719.2 OAJ31594.1 - 0.0058 15.6 0.1 0.068 12.1 0.0 2.6 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain Aminoglyc_resit PF10706.4 OAJ31594.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase zf-C2H2_4 PF13894.1 OAJ31595.1 - 4.5e-07 29.7 12.0 0.01 16.1 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ31595.1 - 4.6e-07 29.7 13.2 2.3e-06 27.6 1.4 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ31595.1 - 3.5e-06 27.0 11.8 0.031 14.6 0.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 OAJ31595.1 - 0.025 14.7 2.6 0.025 14.7 1.8 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RINGv PF12906.2 OAJ31596.1 - 1.6e-06 28.0 7.1 5.3e-06 26.3 1.7 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 OAJ31596.1 - 0.0081 15.9 4.0 0.0081 15.9 2.8 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_4 PF14570.1 OAJ31596.1 - 0.32 10.6 1.8 0.75 9.4 1.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 OAJ31596.1 - 1.1 9.2 4.7 0.42 10.6 1.1 1.8 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 OAJ31596.1 - 2.1 8.4 5.2 12 5.9 2.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 OAJ31596.1 - 7.4 6.7 7.8 21 5.3 5.4 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger UCH PF00443.24 OAJ31597.1 - 3.8e-48 163.9 0.0 4.6e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ31597.1 - 1.1e-20 74.3 0.0 2.5e-20 73.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 OAJ31597.1 - 2.3e-08 33.2 0.0 5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 OAJ31597.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain DUF4106 PF13388.1 OAJ31598.1 - 0.58 9.0 4.5 0.7 8.7 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) TIMELESS PF04821.9 OAJ31599.1 - 7e-42 143.5 4.3 2.3e-41 141.8 0.0 3.2 2 1 0 2 2 2 1 Timeless protein RasGEF PF00617.14 OAJ31600.1 - 1e-41 142.7 0.0 2.1e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 OAJ31600.1 - 8.7e-19 67.5 0.0 1.7e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 OAJ31600.1 - 2.9e-14 52.3 0.1 6.1e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ31600.1 - 3.6e-14 51.9 0.1 8.4e-14 50.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ31600.1 - 4.6e-13 48.3 0.0 8.1e-13 47.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain RhoGAP PF00620.22 OAJ31600.1 - 0.27 10.8 0.0 8.1 6.0 0.0 2.3 2 0 0 2 2 2 0 RhoGAP domain Pkinase PF00069.20 OAJ31601.1 - 1.5e-21 76.7 0.0 3.3e-21 75.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ31601.1 - 1.6e-05 24.1 0.0 5.4e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ31601.1 - 0.0084 15.0 0.0 0.016 14.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ31601.1 - 0.05 12.6 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ31601.1 - 0.051 13.2 0.2 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family KH_1 PF00013.24 OAJ31605.1 - 8.3e-40 134.2 13.1 5.1e-16 58.0 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 OAJ31605.1 - 1e-29 101.5 12.1 1.2e-10 40.7 1.7 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 OAJ31605.1 - 3e-10 39.5 6.9 0.0038 16.7 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 OAJ31605.1 - 1.4e-07 31.0 0.9 0.17 11.5 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 OAJ31605.1 - 0.031 14.0 5.1 1.4 8.7 0.1 3.1 3 0 0 3 3 3 0 NusA-like KH domain dUTPase PF00692.14 OAJ31605.1 - 0.041 13.3 1.3 0.26 10.7 0.1 2.6 3 0 0 3 3 3 0 dUTPase Complex1_LYR_1 PF13232.1 OAJ31606.1 - 1.2e-06 28.5 0.6 1.9e-06 27.9 0.3 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 OAJ31606.1 - 1.5e-05 24.6 0.7 2.4e-05 24.0 0.5 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 OAJ31606.1 - 0.074 13.5 0.9 0.11 12.9 0.6 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Ldh_1_N PF00056.18 OAJ31607.1 - 0.012 15.4 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ABC_tran PF00005.22 OAJ31608.1 - 1.2e-47 161.7 0.0 2.3e-26 92.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 OAJ31608.1 - 1.3e-45 155.9 17.9 2.6e-19 69.7 2.0 4.1 3 1 1 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.14 OAJ31608.1 - 1.2e-11 44.2 0.3 2.7e-05 23.5 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 OAJ31608.1 - 2.9e-06 26.8 0.0 0.027 13.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 OAJ31608.1 - 4e-06 26.4 0.0 0.042 13.3 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_29 PF13555.1 OAJ31608.1 - 1.1e-05 24.9 0.8 0.1 12.1 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 OAJ31608.1 - 2.1e-05 24.4 2.0 0.036 13.8 0.2 2.6 3 0 0 3 3 2 2 Dynamin family Miro PF08477.8 OAJ31608.1 - 4.1e-05 24.0 0.0 0.16 12.4 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_21 PF13304.1 OAJ31608.1 - 5.5e-05 23.2 4.5 3.8 7.3 0.0 4.5 5 0 0 5 5 4 1 AAA domain DUF258 PF03193.11 OAJ31608.1 - 8.4e-05 21.8 0.1 0.14 11.3 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 OAJ31608.1 - 0.00023 21.0 0.6 0.36 10.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 OAJ31608.1 - 0.0003 21.1 0.1 0.09 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 OAJ31608.1 - 0.00031 19.8 0.6 0.54 9.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.18 OAJ31608.1 - 0.00033 20.6 0.0 0.83 9.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 OAJ31608.1 - 0.0008 20.2 0.0 0.1 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 OAJ31608.1 - 0.00096 18.6 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 OAJ31608.1 - 0.0011 19.1 0.3 1.9 8.6 0.0 3.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 OAJ31608.1 - 0.0046 15.8 0.0 2.7 6.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein IstB_IS21 PF01695.12 OAJ31608.1 - 0.027 13.8 0.1 1.7 8.0 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF815 PF05673.8 OAJ31608.1 - 0.028 13.3 0.2 3.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 OAJ31608.1 - 0.048 13.6 4.8 1.7 8.6 0.3 3.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 OAJ31608.1 - 0.069 13.4 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 OAJ31608.1 - 0.1 12.4 2.3 12 5.7 0.1 2.8 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 OAJ31608.1 - 0.11 12.4 0.7 0.96 9.4 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 OAJ31608.1 - 0.18 11.4 0.2 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Striatin PF08232.7 OAJ31610.1 - 0.00093 19.5 0.3 0.00093 19.5 0.2 2.4 3 0 0 3 3 3 1 Striatin family AICARFT_IMPCHas PF01808.13 OAJ31611.1 - 0.0019 17.3 0.0 0.0025 16.9 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme Aminotran_1_2 PF00155.16 OAJ31612.1 - 1.1e-54 185.7 0.0 2e-54 184.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAJ31612.1 - 0.032 13.3 0.0 0.091 11.8 0.0 1.8 2 1 0 2 2 2 0 Beta-eliminating lyase adh_short PF00106.20 OAJ31613.1 - 1.9e-18 66.9 0.7 4.6e-18 65.6 0.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ31613.1 - 1.1e-08 34.9 0.2 2.2e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ31613.1 - 0.00029 20.7 0.0 0.00041 20.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAJ31613.1 - 0.00057 19.9 0.3 0.0026 17.8 0.1 2.0 1 1 0 2 2 2 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 OAJ31613.1 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 OAJ31613.1 - 0.014 15.8 0.2 0.029 14.7 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 OAJ31613.1 - 0.017 14.7 0.2 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mito_carr PF00153.22 OAJ31614.1 - 6.5e-70 230.9 13.6 1.2e-23 82.6 0.1 5.2 4 1 0 4 4 4 4 Mitochondrial carrier protein Pkinase PF00069.20 OAJ31615.1 - 1.8e-64 217.4 0.0 2.2e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ31615.1 - 4.9e-38 130.6 0.0 8.1e-37 126.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ31615.1 - 0.00078 18.4 0.0 0.0029 16.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAJ31615.1 - 0.072 12.8 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ31615.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 OAJ31615.1 - 0.11 11.8 0.1 0.42 9.9 0.0 1.8 1 1 1 2 2 2 0 RIO1 family Mid2 PF04478.7 OAJ31618.1 - 0.079 12.3 0.2 0.14 11.6 0.2 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.1 OAJ31618.1 - 0.15 12.4 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain AAA PF00004.24 OAJ31619.1 - 1.1e-40 138.9 0.0 2.2e-40 137.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 OAJ31619.1 - 4.7e-26 90.4 0.1 2.1e-25 88.3 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 OAJ31619.1 - 1.7e-21 75.8 6.4 4.7e-21 74.4 4.5 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 OAJ31619.1 - 6.4e-05 23.1 0.4 0.0058 16.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ31619.1 - 7.2e-05 23.5 0.2 0.00031 21.5 0.0 2.2 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 OAJ31619.1 - 9.1e-05 21.9 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 OAJ31619.1 - 9.5e-05 21.2 0.4 0.0002 20.1 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 OAJ31619.1 - 0.00018 21.2 0.0 0.00057 19.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 OAJ31619.1 - 0.00022 21.1 1.1 0.00033 20.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 OAJ31619.1 - 0.00024 20.2 0.0 0.00045 19.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 OAJ31619.1 - 0.00031 20.6 0.2 0.0013 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ31619.1 - 0.00082 19.3 0.9 0.011 15.7 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 OAJ31619.1 - 0.001 18.4 0.8 0.27 10.5 0.1 2.7 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.17 OAJ31619.1 - 0.0013 18.8 0.0 0.027 14.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.9 OAJ31619.1 - 0.0036 17.2 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 OAJ31619.1 - 0.011 14.7 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 OAJ31619.1 - 0.012 14.8 0.0 0.027 13.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 OAJ31619.1 - 0.043 12.9 0.0 5.1 6.1 0.0 2.3 1 1 1 2 2 2 0 KaiC AAA_24 PF13479.1 OAJ31619.1 - 0.063 12.8 0.2 0.14 11.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.1 OAJ31619.1 - 0.07 12.8 0.0 0.27 11.0 0.0 2.0 2 0 0 2 2 1 0 Part of AAA domain PhoH PF02562.11 OAJ31619.1 - 0.09 11.9 0.6 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_10 PF12846.2 OAJ31619.1 - 0.096 12.1 0.8 0.96 8.8 0.1 2.5 4 0 0 4 4 3 0 AAA-like domain Sigma54_activat PF00158.21 OAJ31619.1 - 0.1 12.0 0.0 0.63 9.5 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 OAJ31619.1 - 0.14 11.8 0.0 0.89 9.1 0.0 2.3 2 1 1 3 3 2 0 NACHT domain DUF4407 PF14362.1 OAJ31619.1 - 9.2 5.1 9.2 0.17 10.7 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pro_isomerase PF00160.16 OAJ31621.1 - 9.9e-51 172.0 0.0 1.1e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PEMT PF04191.8 OAJ31622.1 - 1e-20 73.7 1.2 1e-20 73.7 0.8 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 OAJ31623.1 - 7.7e-121 403.6 21.5 9.1e-121 403.3 14.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Hydrolase_like PF13242.1 OAJ31625.1 - 3.5e-07 29.8 0.0 5.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 OAJ31625.1 - 1.2e-05 25.6 0.0 1.6e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 OAJ31625.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 1 1 2 2 2 0 Mitochondrial PGP phosphatase WD40 PF00400.27 OAJ31626.1 - 2.1e-06 27.3 0.6 0.015 15.1 0.1 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat Sugar_tr PF00083.19 OAJ31627.1 - 1.2e-44 152.6 18.2 1.3e-24 86.6 0.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ31627.1 - 6.3e-17 61.3 33.7 2.6e-08 32.9 8.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M16 PF00675.15 OAJ31628.1 - 6.5e-17 61.6 0.0 1.6e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 OAJ31628.1 - 1.4e-08 34.6 0.0 3.1e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain E1-E2_ATPase PF00122.15 OAJ31629.1 - 1.9e-14 53.2 0.0 5.2e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 OAJ31629.1 - 8.8e-13 48.8 0.1 2.5e-12 47.3 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ31629.1 - 1e-12 47.7 0.0 3.4e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 OAJ31629.1 - 6.7e-11 42.9 0.1 9.6e-05 22.8 0.0 4.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ31629.1 - 0.00081 19.0 0.6 0.0064 16.1 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TPR_11 PF13414.1 OAJ31630.1 - 8.2e-26 89.4 10.6 9.4e-18 63.6 2.2 2.6 3 0 0 3 3 2 2 TPR repeat TPR_1 PF00515.23 OAJ31630.1 - 9.3e-24 82.0 1.9 5.2e-09 35.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ31630.1 - 6.3e-17 60.0 9.6 1.5e-07 30.8 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ31630.1 - 2.2e-13 49.2 0.6 1.3e-06 28.1 0.1 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ31630.1 - 5.8e-10 39.5 9.2 8.7e-06 26.2 3.3 4.0 2 2 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ31630.1 - 7.3e-10 37.9 1.1 1e-05 24.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ31630.1 - 4e-09 35.5 1.8 0.0012 18.4 0.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ31630.1 - 1.6e-08 34.4 5.9 9.5e-06 25.8 0.1 4.8 3 1 3 6 6 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ31630.1 - 2.3e-08 34.2 0.7 0.0013 19.0 0.2 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ31630.1 - 2.1e-07 30.7 1.3 2.1e-07 30.7 0.9 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 OAJ31630.1 - 0.00017 21.6 0.3 0.0003 20.8 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 OAJ31630.1 - 0.0006 19.6 1.9 0.0071 16.2 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ31630.1 - 0.00065 19.4 4.3 0.011 15.6 0.7 3.0 3 1 1 4 4 3 2 Tetratricopeptide repeat RPN7 PF10602.4 OAJ31630.1 - 0.013 14.9 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Med13_N PF11597.3 OAJ31630.1 - 0.066 11.8 0.8 0.11 11.2 0.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal BTAD PF03704.12 OAJ31630.1 - 0.075 13.3 0.3 0.075 13.3 0.2 3.1 3 1 0 3 3 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 OAJ31630.1 - 0.12 12.8 5.8 2.8 8.6 0.2 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.3 OAJ31630.1 - 2.8 6.5 10.6 0.2 10.3 0.4 2.8 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 PPDFL PF15060.1 OAJ31630.1 - 4.2 7.4 8.7 0.92 9.5 0.3 2.7 3 0 0 3 3 2 0 Differentiation and proliferation regulator SR-25 PF10500.4 OAJ31630.1 - 7.3 5.9 12.5 5.1 6.4 1.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ornatin PF02088.10 OAJ31632.1 - 0.36 10.4 3.3 0.75 9.4 2.3 1.5 1 0 0 1 1 1 0 Ornatin SnoaL_2 PF12680.2 OAJ31633.1 - 0.023 15.1 0.2 0.036 14.4 0.2 1.4 1 1 0 1 1 1 0 SnoaL-like domain VHS PF00790.14 OAJ31634.1 - 9.6e-20 70.6 0.0 2.1e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 OAJ31634.1 - 0.00012 21.9 0.9 0.00035 20.4 0.6 1.7 1 0 0 1 1 1 1 GAT domain Atrophin-1 PF03154.10 OAJ31634.1 - 0.0042 15.3 9.6 0.0042 15.3 6.6 1.7 2 0 0 2 2 2 1 Atrophin-1 family Acyltransferase PF01553.16 OAJ31636.1 - 2.4e-10 39.9 0.0 0.00024 20.5 0.0 2.5 2 0 0 2 2 2 2 Acyltransferase Nop14 PF04147.7 OAJ31636.1 - 1.1 7.0 6.5 2.1 6.1 4.5 1.4 1 0 0 1 1 1 0 Nop14-like family Complex1_49kDa PF00346.14 OAJ31637.1 - 7.8e-128 425.1 0.0 8.9e-128 424.9 0.0 1.0 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Thioredoxin PF00085.15 OAJ31638.1 - 1.1e-25 89.2 0.0 1.9e-21 75.7 0.0 2.8 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.1 OAJ31638.1 - 3.5e-07 30.3 0.5 3.6e-06 27.1 0.2 2.6 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 OAJ31638.1 - 0.0001 22.2 0.1 0.0021 18.0 0.0 2.7 2 2 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.1 OAJ31638.1 - 0.0023 18.0 0.2 0.026 14.6 0.1 2.5 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 OAJ31638.1 - 0.0056 16.3 0.0 0.016 14.8 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA family MAS20 PF02064.10 OAJ31639.1 - 6.7e-17 61.5 0.5 1.5e-15 57.1 0.4 2.2 1 1 0 1 1 1 1 MAS20 protein import receptor Nop14 PF04147.7 OAJ31639.1 - 1.5 6.6 4.5 2.3 6.0 3.1 1.2 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 OAJ31639.1 - 6.1 7.2 6.2 9.8 6.5 0.8 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PNPOx_C PF10590.4 OAJ31640.1 - 6e-20 70.4 3.4 1.1e-19 69.6 2.3 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 OAJ31640.1 - 7.5e-17 61.1 0.1 8.5e-16 57.7 0.0 2.2 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase COPIIcoated_ERV PF07970.7 OAJ31641.1 - 2.1e-61 207.3 4.8 5.9e-33 114.3 0.3 2.7 2 1 0 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 OAJ31641.1 - 3.6e-31 106.9 0.2 1e-30 105.5 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Proteasome PF00227.21 OAJ31642.1 - 2.5e-52 176.9 0.0 3.1e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAJ31642.1 - 6e-14 51.0 0.1 1e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RNase_H2_suC PF08615.6 OAJ31643.1 - 6.5e-13 48.7 26.2 9.4e-13 48.1 2.0 5.3 3 2 0 3 3 3 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) TPR_12 PF13424.1 OAJ31644.1 - 0.094 12.6 0.1 0.27 11.1 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3357 PF11837.3 OAJ31645.1 - 2.9 7.7 7.7 2.2 8.1 0.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3357) ETC_C1_NDUFA4 PF04800.7 OAJ31646.1 - 4.9e-31 106.5 0.1 8.4e-31 105.8 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region SR-25 PF10500.4 OAJ31646.1 - 0.54 9.6 10.0 0.75 9.2 6.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF566 PF04484.7 OAJ31646.1 - 6.6 6.1 11.2 8.6 5.7 7.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) TRIC PF05197.8 OAJ31647.1 - 0.0016 17.8 0.1 0.0054 16.1 0.0 1.8 1 1 0 1 1 1 1 TRIC channel UPF0126 PF03458.8 OAJ31647.1 - 0.0055 16.2 6.9 0.1 12.2 0.6 3.1 3 1 0 3 3 3 2 UPF0126 domain PCI PF01399.22 OAJ31648.1 - 6e-13 49.0 0.0 1.5e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 PCI domain SSP160 PF06933.6 OAJ31648.1 - 0.027 12.4 2.6 0.036 12.0 1.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CTP_transf_2 PF01467.21 OAJ31650.1 - 3.7e-14 53.0 0.0 6.1e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase DUF2457 PF10446.4 OAJ31650.1 - 1.5e-05 23.9 14.2 2.7e-05 23.1 9.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) YL1 PF05764.8 OAJ31650.1 - 0.00011 21.8 8.8 0.00019 21.1 6.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Daxx PF03344.10 OAJ31650.1 - 0.0022 16.5 18.3 0.0039 15.7 12.7 1.3 1 0 0 1 1 1 1 Daxx Family SDA1 PF05285.7 OAJ31650.1 - 0.35 10.1 14.9 0.61 9.3 10.3 1.3 1 0 0 1 1 1 0 SDA1 Nucleoplasmin PF03066.10 OAJ31650.1 - 2.4 7.6 19.0 5.4 6.5 13.2 1.6 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 OAJ31650.1 - 6.2 5.9 16.3 12 5.0 11.3 1.4 1 0 0 1 1 1 0 NOA36 protein Atx10homo_assoc PF09759.4 OAJ31651.1 - 6.6e-17 61.1 0.0 9.3e-16 57.4 0.0 2.7 2 1 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Neuropeptide_S PF14993.1 OAJ31651.1 - 0.074 12.7 0.1 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Neuropeptide S precursor protein Synthase_beta PF11421.3 OAJ31651.1 - 0.13 12.9 0.1 0.13 12.9 0.1 3.5 3 0 0 3 3 3 0 ATP synthase F1 beta subunit Med31 PF05669.7 OAJ31652.1 - 5.4e-28 96.7 0.0 6.3e-28 96.5 0.0 1.1 1 0 0 1 1 1 1 SOH1 DUF1708 PF08101.6 OAJ31653.1 - 1.1e-13 50.8 1.2 1.2e-09 37.5 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF1708) RhoGAP PF00620.22 OAJ31653.1 - 0.0087 15.6 0.0 2.6 7.6 0.0 2.4 2 0 0 2 2 2 2 RhoGAP domain Mucin PF01456.12 OAJ31654.1 - 0.59 9.8 17.7 1.1 9.0 12.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SIR2 PF02146.12 OAJ31655.1 - 1.2e-25 90.3 0.1 3.7e-19 69.1 0.0 3.8 3 1 0 3 3 3 2 Sir2 family Histone PF00125.19 OAJ31656.1 - 6.5e-29 99.8 0.4 1e-28 99.2 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ31656.1 - 0.059 13.5 0.1 0.093 12.9 0.1 1.3 1 0 0 1 1 1 0 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAJ31656.1 - 0.089 12.8 0.1 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BAR PF03114.13 OAJ31657.1 - 4.3e-50 170.3 2.0 5.1e-50 170.1 1.4 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 OAJ31657.1 - 0.0002 20.7 1.3 0.00025 20.4 0.9 1.1 1 0 0 1 1 1 1 Arfaptin-like domain AAA_13 PF13166.1 OAJ31657.1 - 0.088 11.2 1.1 0.11 10.9 0.8 1.2 1 0 0 1 1 1 0 AAA domain zf-CCCH PF00642.19 OAJ31658.1 - 1.8e-07 30.6 25.4 3.7e-05 23.2 1.8 4.5 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Chalcone PF02431.10 OAJ31659.1 - 8.1e-43 146.1 0.0 1.1e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase MCM PF00493.18 OAJ31660.1 - 1.1e-142 474.8 0.2 1.3e-142 474.4 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 OAJ31660.1 - 1.5e-16 61.0 0.0 4e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 OAJ31660.1 - 1.8e-06 27.2 0.0 0.00045 19.4 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 OAJ31660.1 - 7.3e-06 25.7 0.0 1.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 OAJ31660.1 - 0.00018 21.1 0.0 0.0025 17.4 0.0 2.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAJ31660.1 - 0.023 14.1 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 OAJ31660.1 - 0.041 14.2 0.3 0.15 12.4 0.2 2.1 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 OAJ31660.1 - 0.09 12.9 0.2 0.53 10.4 0.0 2.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Telomere_reg-2 PF10193.4 OAJ31661.1 - 3.3e-25 88.5 0.0 8.1e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein Mito_carr PF00153.22 OAJ31662.1 - 2.3e-56 187.5 1.4 6e-18 64.3 0.1 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein SNF2_N PF00176.18 OAJ31663.1 - 2e-81 273.0 0.0 3.4e-81 272.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 OAJ31663.1 - 8.1e-38 128.7 0.2 3.4e-37 126.7 0.1 2.2 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 OAJ31663.1 - 2.3e-30 105.2 3.5 2.3e-30 105.2 2.4 3.1 3 0 0 3 3 2 1 HAND Helicase_C PF00271.26 OAJ31663.1 - 2.4e-14 52.9 0.0 2e-13 50.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ31663.1 - 5.9e-09 36.0 0.0 5.5e-08 32.8 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ31663.1 - 2.7e-07 30.2 0.0 7.5e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HWE_HK PF07536.9 OAJ31663.1 - 0.0016 18.8 1.1 0.23 11.9 0.0 3.1 2 0 0 2 2 2 1 HWE histidine kinase Myb_DNA-binding PF00249.26 OAJ31663.1 - 0.0067 16.4 0.0 0.15 12.1 0.0 3.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain DEAD_2 PF06733.10 OAJ31663.1 - 0.0084 15.5 0.2 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 DBINO PF13892.1 OAJ31663.1 - 0.0084 16.1 5.0 0.0084 16.1 3.5 4.0 3 0 0 3 3 1 1 DNA-binding domain AAA_14 PF13173.1 OAJ31663.1 - 0.011 15.6 0.2 0.046 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 OAJ31663.1 - 0.079 13.1 1.0 0.27 11.3 0.1 2.4 3 0 0 3 3 3 0 AAA domain Ribosomal_L28e PF01778.12 OAJ31664.1 - 9.7e-28 96.9 0.5 1.6e-27 96.2 0.3 1.3 1 0 0 1 1 1 1 Ribosomal L28e protein family Glyco_hydro_108 PF05838.7 OAJ31664.1 - 0.13 12.4 0.1 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 108 Sec1 PF00995.18 OAJ31665.1 - 1e-13 50.8 0.0 1e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF3182 PF11379.3 OAJ31665.1 - 0.04 12.6 0.0 0.055 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) CBFD_NFYB_HMF PF00808.18 OAJ31666.1 - 1e-20 73.5 0.1 1.8e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAJ31666.1 - 9.9e-06 25.5 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF2613 PF11021.3 OAJ31666.1 - 0.098 12.3 1.4 0.19 11.4 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) PBP1_TM PF14812.1 OAJ31666.1 - 5.1 7.4 10.0 9.2 6.6 6.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Prefoldin PF02996.12 OAJ31667.1 - 3.5e-30 104.1 0.0 4.6e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Syntaxin-6_N PF09177.6 OAJ31667.1 - 0.024 15.0 2.1 0.78 10.1 0.1 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Rabaptin PF03528.10 OAJ31667.1 - 0.046 13.6 1.6 0.061 13.2 0.4 1.7 2 0 0 2 2 2 0 Rabaptin Cortex-I_coil PF09304.5 OAJ31667.1 - 0.35 10.9 5.0 2.9 7.9 0.3 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil AAA_13 PF13166.1 OAJ31668.1 - 0.084 11.3 8.7 0.11 10.8 6.0 1.1 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 OAJ31668.1 - 0.13 11.4 20.0 0.063 12.4 12.1 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 OAJ31668.1 - 2.4 7.1 14.7 3.9 6.4 10.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3246 PF11596.3 OAJ31668.1 - 4.6 6.4 10.1 0.037 13.2 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) DUF465 PF04325.8 OAJ31668.1 - 5.8 6.6 13.6 0.095 12.4 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Atg14 PF10186.4 OAJ31668.1 - 6.4 5.6 15.7 2.7 6.8 7.7 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Mito_carr PF00153.22 OAJ31669.1 - 1.2e-27 95.3 8.1 5e-14 51.7 0.0 3.3 2 1 0 3 3 3 3 Mitochondrial carrier protein Vps53_N PF04100.7 OAJ31670.1 - 6e-85 285.3 2.6 9.7e-85 284.6 1.8 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 OAJ31670.1 - 0.0049 15.8 6.0 0.0095 14.8 4.2 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 OAJ31670.1 - 0.038 13.7 3.3 0.11 12.2 2.3 1.7 1 0 0 1 1 1 0 Exocyst complex component Sec5 PGC7_Stella PF15549.1 OAJ31670.1 - 1.2 9.1 4.9 0.51 10.3 0.1 2.3 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain Baculo_PEP_C PF04513.7 OAJ31670.1 - 4.2 7.1 9.3 8.5 6.1 4.9 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Copper-fist PF00649.13 OAJ31672.1 - 1.4e-14 53.0 0.3 3.3e-14 51.7 0.2 1.7 1 0 0 1 1 1 1 Copper fist DNA binding domain TPR_14 PF13428.1 OAJ31673.1 - 1.1e-18 65.9 26.0 0.0085 16.6 0.0 11.1 8 2 5 13 13 10 7 Tetratricopeptide repeat HAT PF02184.11 OAJ31673.1 - 1.1e-17 63.3 56.7 2.4e-09 36.7 0.4 14.3 16 0 0 16 16 15 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 OAJ31673.1 - 1.6e-12 47.5 1.7 0.033 14.5 0.0 6.6 4 3 3 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ31673.1 - 2e-09 36.9 2.7 0.31 10.7 0.0 6.4 4 2 3 7 7 7 3 TPR repeat TPR_12 PF13424.1 OAJ31673.1 - 2.3e-08 33.8 4.7 4.2 7.3 0.1 5.8 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ31673.1 - 5.6e-08 32.1 5.5 3 7.9 0.0 7.5 8 1 1 9 9 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ31673.1 - 3.4e-07 30.7 18.3 0.00039 20.9 0.1 6.9 4 2 4 9 9 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ31673.1 - 0.00058 19.4 0.0 2.5 8.1 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ31673.1 - 0.0015 18.0 1.0 66 3.3 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ31673.1 - 0.0079 16.3 0.0 1.5 9.1 0.0 3.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ31673.1 - 0.026 14.3 17.4 3.5 7.6 0.0 8.5 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ31673.1 - 0.046 14.1 5.2 77 4.0 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 OAJ31673.1 - 0.11 12.2 11.4 0.24 11.2 0.2 4.8 4 1 1 5 5 5 0 U3 small nucleolar RNA-associated protein 6 Nucleoplasmin PF03066.10 OAJ31673.1 - 2.5 7.5 13.3 0.89 9.0 1.5 2.7 3 0 0 3 3 3 0 Nucleoplasmin CENP-B_dimeris PF09026.5 OAJ31673.1 - 6.3 7.0 17.0 13 6.1 2.4 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 OAJ31673.1 - 7.1 6.8 10.7 13 5.9 2.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Acetyltransf_1 PF00583.19 OAJ31675.1 - 1.6e-05 24.7 0.0 3.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ31675.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain 6PF2K PF01591.13 OAJ31676.1 - 2.6e-69 232.7 0.0 3.8e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 OAJ31676.1 - 7.8e-31 107.2 0.0 1.7e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 OAJ31676.1 - 2.8e-09 36.9 0.0 6.3e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ31676.1 - 0.0003 21.5 0.0 0.0046 17.7 0.0 2.3 1 1 0 2 2 2 1 AAA domain GBP PF02263.14 OAJ31676.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain NO_synthase PF02898.10 OAJ31676.1 - 0.16 10.5 0.0 0.27 9.8 0.0 1.3 1 0 0 1 1 1 0 Nitric oxide synthase, oxygenase domain KTI12 PF08433.5 OAJ31676.1 - 0.19 10.8 0.0 0.58 9.3 0.0 1.7 1 1 0 1 1 1 0 Chromatin associated protein KTI12 TIG PF01833.19 OAJ31677.1 - 2.6e-12 46.5 1.2 2.3e-11 43.5 1.2 2.3 2 0 0 2 2 2 1 IPT/TIG domain Ank PF00023.25 OAJ31677.1 - 8.8e-12 44.2 2.2 1.9e-05 24.2 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 OAJ31677.1 - 4.4e-11 42.6 0.6 4.6e-10 39.4 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 OAJ31677.1 - 5.9e-11 42.5 0.0 1.3e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ31677.1 - 5.6e-09 36.2 1.7 1.2e-08 35.2 1.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ31677.1 - 0.00011 22.0 0.9 0.029 14.5 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Kinesin PF00225.18 OAJ31678.1 - 6.3e-111 370.2 0.0 2.2e-110 368.5 0.0 2.0 1 0 0 1 1 1 1 Kinesin motor domain Sox_N PF12444.3 OAJ31678.1 - 2.5 9.2 0.0 2.5 9.2 0.0 4.2 3 2 0 3 3 3 0 Sox developmental protein N terminal Filament PF00038.16 OAJ31678.1 - 9.8 5.5 79.6 0.16 11.4 31.6 3.8 3 1 2 5 5 5 0 Intermediate filament protein Ribosomal_S21e PF01249.13 OAJ31679.1 - 1.8e-34 117.5 0.0 2e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e SpoA PF01052.15 OAJ31679.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) PUA_2 PF14306.1 OAJ31679.1 - 0.069 12.5 0.0 0.085 12.2 0.0 1.0 1 0 0 1 1 1 0 PUA-like domain Rrn6 PF10214.4 OAJ31680.1 - 9.4e-05 20.7 8.2 9.7e-05 20.6 5.3 1.2 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DUF605 PF04652.11 OAJ31680.1 - 0.68 9.2 21.9 0.018 14.4 10.4 1.8 2 0 0 2 2 2 0 Vta1 like Serinc PF03348.10 OAJ31680.1 - 0.79 8.3 9.5 1.2 7.7 6.6 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Baculo_PP31 PF05311.6 OAJ31680.1 - 2.6 7.2 11.9 5.8 6.0 8.3 1.6 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Zip PF02535.17 OAJ31680.1 - 3.1 6.7 7.3 5.4 5.9 5.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Ndc1_Nup PF09531.5 OAJ31680.1 - 4.5 5.5 11.3 6.3 5.0 7.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.4 OAJ31680.1 - 5 5.2 40.7 1.3 7.2 25.5 1.8 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4106 PF13388.1 OAJ31680.1 - 6.2 5.6 26.5 10 4.9 18.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) RR_TM4-6 PF06459.7 OAJ31680.1 - 6.6 6.5 18.2 0.3 10.9 8.5 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 OAJ31680.1 - 6.8 6.4 16.7 0.32 10.7 7.2 1.9 2 1 0 2 2 2 0 DDHD domain DPBB_1 PF03330.13 OAJ31681.1 - 8.5e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ31681.1 - 0.0011 18.5 0.0 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 Barwin family Sybindin PF04099.7 OAJ31682.1 - 1.2e-39 135.2 0.0 1.3e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 OAJ31682.1 - 1.5e-07 31.3 0.0 1.5e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region PilP PF04351.8 OAJ31682.1 - 0.15 11.9 0.0 0.44 10.4 0.0 1.8 1 1 1 2 2 2 0 Pilus assembly protein, PilP Asp PF00026.18 OAJ31683.1 - 3.6e-47 161.1 0.0 4.5e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ31683.1 - 9.1e-07 28.9 0.1 2e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal DUF4544 PF15077.1 OAJ31683.1 - 0.32 10.4 1.1 0.5 9.8 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) NTF2 PF02136.15 OAJ31684.1 - 1.3e-28 99.7 0.0 2.3e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 OAJ31684.1 - 0.0003 20.3 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ31684.1 - 0.007 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sel1 PF08238.7 OAJ31686.1 - 5.8e-32 109.4 35.4 6.6e-08 32.9 0.4 9.6 10 0 0 10 10 10 7 Sel1 repeat HLH PF00010.21 OAJ31686.1 - 1.8e-14 53.1 5.2 2.5e-09 36.6 0.2 2.9 2 1 1 3 3 3 2 Helix-loop-helix DNA-binding domain EF-hand_1 PF00036.27 OAJ31687.1 - 6.6e-42 137.6 13.4 2e-10 39.1 0.7 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 OAJ31687.1 - 1.2e-37 127.7 3.4 1.3e-20 73.2 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 OAJ31687.1 - 3.6e-33 112.9 10.6 3.7e-16 58.4 0.4 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 OAJ31687.1 - 1.7e-31 105.2 7.4 1.8e-09 36.6 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 OAJ31687.1 - 1.2e-28 97.1 7.5 3.3e-07 29.3 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 OAJ31687.1 - 4.5e-15 55.3 0.1 1.9e-08 34.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 OAJ31687.1 - 2.9e-10 39.7 0.6 2.8e-05 23.7 0.2 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 OAJ31687.1 - 4.5e-09 36.3 0.0 0.00032 20.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 OAJ31687.1 - 7.2e-08 31.9 1.1 0.017 14.7 0.0 3.7 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 OAJ31687.1 - 1e-05 25.4 0.7 4.3e-05 23.4 0.2 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 OAJ31687.1 - 0.00056 19.3 1.2 0.00065 19.1 0.9 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.8 OAJ31687.1 - 0.00098 18.7 0.1 0.079 12.5 0.1 2.6 1 1 0 1 1 1 1 Caleosin related protein EF-hand_like PF09279.6 OAJ31687.1 - 0.0016 18.4 0.6 0.0078 16.2 0.1 2.2 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like TerB PF05099.8 OAJ31687.1 - 0.005 16.5 0.2 0.63 9.7 0.0 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB Poly_export PF02563.11 OAJ31687.1 - 0.019 14.7 0.1 2.8 7.7 0.0 3.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis/export protein MotA_activ PF09114.5 OAJ31687.1 - 0.024 14.3 0.3 4.3 7.1 0.1 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain RNA_pol_Rpb4 PF03874.11 OAJ31687.1 - 0.054 13.5 1.1 5.8 6.9 0.0 2.5 3 0 0 3 3 3 0 RNA polymerase Rpb4 Tenui_NCP PF04876.7 OAJ31687.1 - 0.066 12.7 0.1 0.98 8.9 0.0 2.0 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein LNS2 PF08235.8 OAJ31687.1 - 0.069 12.7 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Toprim_2 PF13155.1 OAJ31687.1 - 0.075 13.3 0.6 18 5.7 0.3 2.6 1 1 2 3 3 3 0 Toprim-like DUF853 PF05872.7 OAJ31687.1 - 0.081 11.2 0.0 3.3 5.9 0.0 2.1 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) SapB_1 PF05184.10 OAJ31687.1 - 0.091 12.6 0.1 34 4.4 0.0 3.1 3 0 0 3 3 3 0 Saposin-like type B, region 1 KIP1 PF07765.7 OAJ31687.1 - 0.21 11.4 1.2 4.4 7.2 0.0 3.1 3 1 1 4 4 4 0 KIP1-like protein VCBS PF13517.1 OAJ31687.1 - 2.8 8.3 6.4 17 5.8 0.3 2.5 2 2 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Rxt3 PF08642.5 OAJ31688.1 - 3.7e-15 56.1 0.0 4.8e-11 42.9 0.0 5.8 4 2 1 5 5 5 2 Histone deacetylation protein Rxt3 DDE_1 PF03184.14 OAJ31689.1 - 2.2e-36 125.0 0.0 3.5e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAJ31689.1 - 1.2e-09 37.7 0.0 5.2e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 OAJ31689.1 - 3.4e-06 26.8 0.1 8.4e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease SH3_1 PF00018.23 OAJ31690.1 - 5.4e-25 86.5 0.0 9.2e-12 44.1 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 OAJ31690.1 - 1e-15 57.0 0.0 8.6e-08 31.6 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 OAJ31690.1 - 3.5e-14 52.0 0.0 6.9e-09 35.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 OAJ31690.1 - 1.2e-10 41.1 0.0 2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 OAJ31690.1 - 1.8e-05 24.2 0.0 3.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Sulf_transp PF04143.9 OAJ31691.1 - 1.8e-14 53.4 16.0 1.2e-08 34.7 4.3 4.1 4 0 0 4 4 4 2 Sulphur transport DUF4341 PF14241.1 OAJ31691.1 - 1.6e-10 40.5 0.9 1.6e-10 40.5 0.6 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4341) CD20 PF04103.10 OAJ31691.1 - 0.0043 16.9 0.0 0.018 14.9 0.0 2.0 1 0 0 1 1 1 1 CD20-like family Chorion_2 PF03964.10 OAJ31691.1 - 0.37 11.3 3.5 0.71 10.4 1.7 2.0 1 1 0 1 1 1 0 Chorion family 2 PC_rep PF01851.17 OAJ31692.1 - 7.2e-16 57.4 18.0 0.0015 18.6 0.0 8.9 9 0 0 9 9 9 5 Proteasome/cyclosome repeat Herpes_DNAp_acc PF04929.7 OAJ31692.1 - 2.7 6.8 9.2 4.8 6.0 6.4 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RRM_1 PF00076.17 OAJ31693.1 - 1.2e-34 117.7 0.0 4.9e-20 70.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ31693.1 - 1.9e-30 104.6 0.0 2.8e-15 56.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ31693.1 - 1.3e-22 79.3 0.0 3.9e-08 33.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 OAJ31693.1 - 4.4e-14 52.5 0.1 1e-13 51.3 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 OAJ31693.1 - 0.00015 21.5 0.0 0.00056 19.7 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 OAJ31693.1 - 0.0077 15.9 0.0 0.75 9.6 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif WD40 PF00400.27 OAJ31694.1 - 6e-10 38.6 4.8 2.9e-05 23.7 0.0 6.0 7 0 0 7 7 7 2 WD domain, G-beta repeat eIF2A PF08662.6 OAJ31694.1 - 0.0032 17.1 0.0 4 7.0 0.0 3.8 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 OAJ31694.1 - 0.012 15.2 2.2 2.3 7.9 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 OAJ31694.1 - 0.024 14.3 1.0 7.3 6.2 0.0 3.5 4 0 0 4 4 4 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 OAJ31694.1 - 0.2 9.4 0.0 1.9 6.1 0.0 2.2 2 0 0 2 2 2 0 IKI3 family His_Phos_1 PF00300.17 OAJ31695.1 - 0.0037 17.3 0.0 0.004 17.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) WD40 PF00400.27 OAJ31696.1 - 3.8e-19 67.7 25.3 1.1e-07 31.4 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 OAJ31696.1 - 1.6e-14 53.6 0.0 2.8e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain PBP1_TM PF14812.1 OAJ31696.1 - 0.49 10.7 3.4 0.83 9.9 2.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TBCC PF07986.7 OAJ31697.1 - 7.9e-15 54.3 2.1 7e-14 51.2 0.9 2.2 2 0 0 2 2 2 1 Tubulin binding cofactor C F_actin_bind PF08919.5 OAJ31697.1 - 0.84 9.3 3.5 3.9 7.2 0.4 3.1 1 1 2 3 3 3 0 F-actin binding E1-E2_ATPase PF00122.15 OAJ31698.1 - 1.4e-22 79.8 0.0 5.7e-22 77.8 0.0 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 OAJ31698.1 - 2.2e-18 67.4 0.0 1.1e-17 65.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAJ31698.1 - 1.3e-11 45.0 0.1 3.8e-11 43.5 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ31698.1 - 4.2e-06 26.6 0.0 1.3e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAJ31698.1 - 0.0014 18.2 0.2 0.0038 16.8 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acetyltransf_1 PF00583.19 OAJ31699.1 - 2.1e-10 40.4 0.0 4.1e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ31699.1 - 3.4e-06 27.1 0.0 6.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 OAJ31699.1 - 3.6e-05 23.9 0.0 6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAJ31699.1 - 0.008 16.2 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ31699.1 - 0.017 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein TEA PF01285.13 OAJ31703.1 - 1.8e-31 109.8 0.0 8.5e-31 107.5 0.0 2.1 1 1 0 1 1 1 1 TEA/ATTS domain family NBP1 PF08537.5 OAJ31703.1 - 0.39 9.8 3.2 0.75 8.9 2.2 1.4 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 XdhC_CoxI PF02625.11 OAJ31704.1 - 0.046 13.3 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 XdhC and CoxI family LcrG PF07216.7 OAJ31704.1 - 3.6 7.6 7.4 0.81 9.7 2.0 1.9 1 1 1 2 2 2 0 LcrG protein Lipase_GDSL_2 PF13472.1 OAJ31705.1 - 1.6e-25 90.3 0.0 1.9e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 OAJ31705.1 - 1.3e-22 80.7 0.0 3.9e-22 79.2 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CHORD PF04968.7 OAJ31706.1 - 2.7e-42 142.8 14.4 2.7e-23 81.9 2.0 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 OAJ31706.1 - 7.4e-09 36.0 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 CS domain BTK PF00779.14 OAJ31706.1 - 0.84 9.3 10.2 0.21 11.2 0.8 2.8 2 1 0 2 2 2 0 BTK motif DUF2013 PF09431.5 OAJ31708.1 - 1e-49 167.9 2.0 1.9e-49 167.0 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) XAP5 PF04921.9 OAJ31709.1 - 2.6e-93 311.9 10.8 2.6e-93 311.9 7.5 2.3 1 1 1 2 2 2 1 XAP5, circadian clock regulator Mucin PF01456.12 OAJ31709.1 - 0.16 11.7 10.2 0.25 11.1 7.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein ABC_tran PF00005.22 OAJ31713.1 - 1.7e-14 54.3 0.0 1.3e-13 51.3 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 OAJ31713.1 - 1.3e-07 31.8 0.8 0.00096 19.1 0.4 2.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAJ31713.1 - 0.0011 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 OAJ31713.1 - 0.0016 18.3 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 OAJ31713.1 - 0.0034 17.7 0.0 0.0049 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ31713.1 - 0.0061 16.2 0.1 0.018 14.8 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 OAJ31713.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAJ31713.1 - 0.012 15.0 0.1 0.046 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 OAJ31713.1 - 0.018 14.5 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Guanylate kinase SMC_N PF02463.14 OAJ31713.1 - 0.019 14.1 0.0 0.27 10.4 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SRPRB PF09439.5 OAJ31713.1 - 0.023 13.9 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DAP3 PF10236.4 OAJ31713.1 - 0.036 13.0 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 T2SE PF00437.15 OAJ31713.1 - 0.047 12.5 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 OAJ31713.1 - 0.079 12.8 0.0 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 OAJ31713.1 - 0.087 12.9 0.0 0.33 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 OAJ31713.1 - 0.091 12.6 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 OAJ31713.1 - 0.097 12.6 0.7 0.18 11.8 0.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 OAJ31713.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 OAJ31713.1 - 0.11 11.9 0.0 0.39 10.1 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_17 PF13207.1 OAJ31713.1 - 0.12 13.1 0.3 0.34 11.7 0.0 1.8 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 OAJ31713.1 - 0.13 11.7 0.1 0.63 9.4 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.1 OAJ31713.1 - 0.13 11.2 0.0 0.34 9.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 OAJ31713.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 UCH PF00443.24 OAJ31714.1 - 3e-48 164.2 0.0 4.6e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ31714.1 - 4.5e-21 75.5 0.0 3.9e-11 42.9 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 OAJ31714.1 - 3.5e-20 71.8 9.9 7.9e-18 64.3 1.0 3.2 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 OAJ31714.1 - 3.5e-19 68.0 0.2 4.7e-09 35.8 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain RVT_1 PF00078.22 OAJ31716.1 - 0.0081 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_43 PF04616.9 OAJ31718.1 - 2.7e-35 121.8 0.4 3.1e-35 121.6 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Radical_SAM PF04055.16 OAJ31719.1 - 8e-14 52.1 0.0 1.2e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily DUF1335 PF07056.6 OAJ31719.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) PAP1 PF08601.5 OAJ31719.1 - 2.9 7.4 7.0 4.2 6.9 4.8 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 PP2C PF00481.16 OAJ31721.1 - 4.8e-34 117.9 0.0 1.4e-31 109.8 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C Radical_SAM PF04055.16 OAJ31722.1 - 1.5e-16 60.9 0.4 1e-15 58.2 0.1 2.2 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 OAJ31722.1 - 1.5e-10 40.9 0.0 4.2e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAJ31722.1 - 0.024 14.7 0.1 0.31 11.1 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ31722.1 - 0.085 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Nol1_Nop2_Fmu PF01189.12 OAJ31723.1 - 7.4e-93 310.9 0.0 9.6e-93 310.6 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 OAJ31723.1 - 0.00021 21.3 0.0 0.0004 20.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 OAJ31723.1 - 0.00024 20.7 0.0 0.0004 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 OAJ31723.1 - 0.00052 19.6 0.0 0.00092 18.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.14 OAJ31723.1 - 0.0015 18.1 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SDA1 PF05285.7 OAJ31723.1 - 2.5 7.3 50.5 0.023 13.9 16.0 2.2 2 0 0 2 2 2 0 SDA1 Mannosyl_trans3 PF11051.3 OAJ31724.1 - 1.8e-10 40.6 0.0 2.2e-09 37.0 0.0 2.5 1 1 0 1 1 1 1 Mannosyltransferase putative Gag_p30 PF02093.11 OAJ31724.1 - 0.008 15.4 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Gag P30 core shell protein ECH PF00378.15 OAJ31726.1 - 1.1e-14 54.1 0.0 2.4e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Formyl_trans_N PF00551.14 OAJ31726.1 - 3.9e-11 42.8 0.0 5.7e-10 39.0 0.0 2.5 1 1 1 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.13 OAJ31726.1 - 0.0012 18.8 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Memo PF01875.12 OAJ31730.1 - 1.1e-70 237.6 0.0 2.8e-70 236.3 0.0 1.6 1 1 0 1 1 1 1 Memo-like protein zf-H2C2_2 PF13465.1 OAJ31731.1 - 8.8e-23 79.4 13.2 7.4e-06 26.0 0.5 4.9 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ31731.1 - 2.2e-20 71.7 22.4 9.7e-05 22.4 1.5 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ31731.1 - 2.2e-12 46.3 20.2 0.0017 18.5 0.3 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 OAJ31731.1 - 0.016 15.1 13.7 0.11 12.4 0.6 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-TRAF PF02176.13 OAJ31731.1 - 0.069 13.5 6.6 0.065 13.6 0.7 2.8 1 1 2 3 3 3 0 TRAF-type zinc finger Nop14 PF04147.7 OAJ31731.1 - 0.24 9.2 9.8 0.38 8.6 6.8 1.2 1 0 0 1 1 1 0 Nop14-like family FYDLN_acid PF09538.5 OAJ31731.1 - 1.2 9.7 13.5 0.11 13.0 5.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-met PF12874.2 OAJ31731.1 - 3 8.1 14.2 5.6 7.3 0.3 4.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Chromo PF00385.19 OAJ31732.1 - 5.7e-15 54.7 2.2 1.3e-14 53.5 1.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 OAJ31732.1 - 4.5e-11 42.4 0.0 1.3e-09 37.7 0.0 2.4 2 0 0 2 2 2 1 Chromo shadow domain PCMT PF01135.14 OAJ31733.1 - 4.9e-64 215.7 0.0 1.8e-62 210.5 0.0 2.0 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 OAJ31733.1 - 0.00011 22.6 0.1 0.0028 18.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ31733.1 - 0.015 15.3 0.0 0.036 14.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ31733.1 - 0.031 13.9 0.0 0.048 13.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ31733.1 - 0.085 12.4 0.1 0.26 10.8 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain PIG-H PF10181.4 OAJ31734.1 - 4.8e-07 29.3 0.1 2.9e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Mito_carr PF00153.22 OAJ31735.1 - 1.3e-50 169.0 5.8 2.9e-18 65.3 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein DNA_ligase_A_M PF01068.16 OAJ31736.1 - 2.8e-17 62.7 0.0 2.8e-08 33.3 0.0 4.2 3 1 0 3 3 3 3 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 OAJ31736.1 - 0.0052 16.6 0.1 0.022 14.5 0.0 2.2 2 1 0 2 2 2 1 DNA ligase N terminus PIP5K PF01504.13 OAJ31737.1 - 1.1e-63 214.7 0.0 2.4e-63 213.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 OAJ31737.1 - 7e-25 87.5 0.1 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 OAJ31737.1 - 9.2e-16 57.4 9.2 9.2e-16 57.4 6.3 1.8 2 0 0 2 2 2 1 FYVE zinc finger NRDE-2 PF08424.5 OAJ31737.1 - 0.32 9.8 0.0 0.74 8.6 0.0 1.5 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference LIP PF03583.9 OAJ31738.1 - 5.1e-50 170.3 0.1 6.3e-50 169.9 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 OAJ31738.1 - 3.8e-07 29.9 0.1 9e-07 28.7 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ31738.1 - 5.4e-06 26.4 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ31738.1 - 1.5e-05 24.3 0.2 0.0031 16.7 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family Cutinase PF01083.17 OAJ31738.1 - 0.027 14.2 0.1 0.057 13.1 0.1 1.6 1 0 0 1 1 1 0 Cutinase DUF1804 PF08822.6 OAJ31739.1 - 0.076 12.7 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) bZIP_1 PF00170.16 OAJ31740.1 - 3.1e-07 30.2 10.9 3.1e-07 30.2 7.5 3.5 2 1 3 5 5 5 4 bZIP transcription factor Hap4_Hap_bind PF10297.4 OAJ31740.1 - 8.3e-07 28.6 5.1 8.3e-07 28.6 3.5 2.8 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 V_ATPase_I PF01496.14 OAJ31740.1 - 0.7 7.6 4.4 0.98 7.1 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SNF2_N PF00176.18 OAJ31741.1 - 8e-71 238.2 2.0 1.5e-70 237.3 1.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 OAJ31741.1 - 1.7e-53 180.4 22.3 1.7e-53 180.4 15.4 3.0 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 OAJ31741.1 - 1.7e-12 46.9 0.0 4.2e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ31741.1 - 1.2e-05 25.2 0.1 0.00011 22.1 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit rve PF00665.21 OAJ31744.1 - 7.9e-19 67.9 0.0 1.8e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ31744.1 - 1.5e-16 60.4 0.0 3.4e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 OAJ31744.1 - 0.0064 15.9 0.0 0.043 13.3 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Prenyltrans PF00432.16 OAJ31746.1 - 1.8e-36 123.3 12.1 2.8e-12 45.9 0.2 5.7 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 OAJ31746.1 - 4.8e-26 91.3 1.4 1.1e-11 45.0 0.0 3.6 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 OAJ31746.1 - 2.6e-09 37.0 0.0 8.9e-05 22.4 0.0 3.3 2 1 0 2 2 2 2 Prenyltransferase-like A2M_comp PF07678.9 OAJ31746.1 - 0.018 14.3 0.0 5.6 6.1 0.0 3.6 4 1 0 5 5 5 0 A-macroglobulin complement component LUC7 PF03194.10 OAJ31747.1 - 3e-72 243.2 2.0 3e-72 243.2 1.4 1.3 2 0 0 2 2 2 1 LUC7 N_terminus ArgJ PF01960.13 OAJ31748.1 - 1.1e-125 419.0 0.0 1.9e-125 418.2 0.0 1.3 1 1 0 1 1 1 1 ArgJ family Hist_deacetyl PF00850.14 OAJ31749.1 - 4.1e-79 266.0 0.0 5.4e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain PPR_2 PF13041.1 OAJ31750.1 - 1.2e-31 108.4 7.2 4.3e-11 42.5 0.1 9.4 7 2 4 11 11 11 6 PPR repeat family PPR_3 PF13812.1 OAJ31750.1 - 3e-30 101.9 8.9 0.0003 20.8 0.1 11.7 9 2 2 11 11 11 5 Pentatricopeptide repeat domain PPR PF01535.15 OAJ31750.1 - 3.6e-26 89.2 9.4 1.8e-06 27.5 0.1 11.2 12 0 0 12 12 12 5 PPR repeat PPR_1 PF12854.2 OAJ31750.1 - 2e-11 43.1 7.5 0.00014 21.2 0.0 7.0 7 1 0 7 7 7 2 PPR repeat TPR_7 PF13176.1 OAJ31750.1 - 0.00029 20.4 0.2 3.5 7.6 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ31750.1 - 0.47 10.8 12.3 39 4.6 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat AA_kinase PF00696.23 OAJ31751.1 - 1.3e-36 126.4 0.0 3.1e-31 108.7 0.0 2.2 2 0 0 2 2 2 2 Amino acid kinase family ACT PF01842.20 OAJ31751.1 - 1.1e-08 34.3 0.1 0.00015 21.1 0.0 3.0 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 OAJ31751.1 - 3e-06 26.6 0.2 3e-06 26.6 0.1 2.1 2 0 0 2 2 2 1 ACT domain CopC PF04234.7 OAJ31752.1 - 0.037 14.6 0.6 0.06 13.9 0.0 1.6 2 0 0 2 2 2 0 CopC domain Ssu72 PF04722.8 OAJ31753.1 - 1e-81 272.9 0.0 1.1e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein LMWPc PF01451.16 OAJ31753.1 - 0.034 14.4 0.1 0.077 13.3 0.0 1.6 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase NAD_Gly3P_dh_C PF07479.9 OAJ31753.1 - 0.12 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus FliT PF05400.8 OAJ31754.1 - 0.02 15.2 7.4 0.02 15.2 5.2 1.9 2 1 1 3 3 3 0 Flagellar protein FliT DNA_repr_REX1B PF14966.1 OAJ31754.1 - 0.092 13.1 1.4 6.2 7.2 0.0 3.0 2 1 0 2 2 2 0 DNA repair REX1-B TMF_TATA_bd PF12325.3 OAJ31754.1 - 0.18 11.5 5.4 0.42 10.3 3.7 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.1 OAJ31754.1 - 0.41 9.5 6.9 0.032 13.2 1.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Use1 PF09753.4 OAJ31754.1 - 0.81 9.0 5.6 0.073 12.4 0.9 1.5 2 0 0 2 2 2 0 Membrane fusion protein Use1 Med17 PF10156.4 OAJ31754.1 - 2.4 6.3 9.4 5.7 5.0 6.5 1.8 1 1 0 1 1 1 0 Subunit 17 of Mediator complex Viral_P18 PF04521.8 OAJ31754.1 - 3.2 7.2 4.9 2.6 7.5 0.6 2.2 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF4140 PF13600.1 OAJ31754.1 - 5.2 7.5 10.2 2.1 8.8 4.0 2.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 OAJ31754.1 - 5.3 6.5 10.4 0.6 9.6 3.7 2.0 2 1 0 2 2 2 0 IncA protein HMG_box PF00505.14 OAJ31756.1 - 2e-14 53.6 1.7 2.6e-14 53.2 0.3 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ31756.1 - 8.8e-10 38.8 0.2 1.9e-09 37.7 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain DASH_Dad4 PF08650.5 OAJ31757.1 - 1.3e-18 66.6 0.0 1.5e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 OAJ31757.1 - 0.011 15.4 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 PRMT5 PF05185.11 OAJ31758.1 - 1.7e-147 492.0 0.0 2e-147 491.7 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 OAJ31758.1 - 0.0065 16.9 0.0 0.021 15.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ceramidase PF05875.7 OAJ31759.1 - 4.2e-65 219.4 4.3 4.9e-65 219.2 3.0 1.0 1 0 0 1 1 1 1 Ceramidase HlyIII PF03006.15 OAJ31759.1 - 0.48 9.7 12.1 3.6 6.9 8.4 2.3 1 1 0 1 1 1 0 Haemolysin-III related UPF0542 PF15086.1 OAJ31760.1 - 0.086 12.5 0.0 0.36 10.5 0.0 2.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 ADH_N PF08240.7 OAJ31761.1 - 1.2e-31 108.6 0.2 2.2e-31 107.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ31761.1 - 4.9e-28 97.2 0.1 7.3e-28 96.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 OAJ31761.1 - 0.0012 18.4 0.0 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 OAJ31761.1 - 0.0023 17.9 0.1 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_11 PF08241.7 OAJ31761.1 - 0.023 15.2 0.0 0.094 13.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Saccharop_dh PF03435.13 OAJ31761.1 - 0.049 12.6 0.2 0.07 12.1 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase ADH_N_assoc PF13823.1 OAJ31761.1 - 0.069 12.8 1.0 0.18 11.4 0.7 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Methyltransf_25 PF13649.1 OAJ31761.1 - 0.079 13.3 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF77 PF01910.12 OAJ31762.1 - 5.4e-23 80.4 0.0 6.8e-23 80.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 OAJ31762.1 - 0.00056 20.0 0.0 0.00087 19.3 0.0 1.3 1 0 0 1 1 1 1 YKOF-related Family F-box-like PF12937.2 OAJ31763.1 - 0.0041 16.8 1.4 0.3 10.8 0.1 2.6 2 0 0 2 2 2 2 F-box-like WD40 PF00400.27 OAJ31765.1 - 2.9e-16 58.6 6.8 0.00041 20.1 0.0 5.8 5 1 0 5 5 5 4 WD domain, G-beta repeat OEP PF02321.13 OAJ31765.1 - 0.0045 16.5 0.1 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 Outer membrane efflux protein UQ_con PF00179.21 OAJ31766.1 - 2.9e-22 78.6 0.0 6.5e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 OAJ31766.1 - 0.0053 16.4 0.0 0.0099 15.5 0.0 1.4 1 0 0 1 1 1 1 UEV domain UBA PF00627.26 OAJ31766.1 - 0.03 14.1 0.0 0.083 12.7 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain IBR PF01485.16 OAJ31766.1 - 0.031 14.1 1.5 0.071 12.9 1.0 1.5 1 0 0 1 1 1 0 IBR domain Neur_chan_memb PF02932.11 OAJ31766.1 - 1.9 8.3 4.3 4.1 7.2 3.0 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BUD22 PF09073.5 OAJ31766.1 - 4.1 6.3 31.5 0.33 9.9 9.1 2.4 2 0 0 2 2 2 0 BUD22 RNA_pol_Rpb2_6 PF00562.23 OAJ31767.1 - 1.4e-122 409.2 0.0 2e-122 408.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 OAJ31767.1 - 4.4e-57 192.2 0.2 7e-57 191.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 OAJ31767.1 - 1.3e-33 116.0 0.2 2.6e-33 115.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 OAJ31767.1 - 2.3e-26 91.8 0.0 6.6e-26 90.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 OAJ31767.1 - 6.1e-23 80.4 0.3 1.5e-22 79.1 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 OAJ31767.1 - 7.6e-21 73.6 0.0 1.7e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 OAJ31767.1 - 7.3e-13 48.2 0.3 2.2e-12 46.7 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 OAJ31767.1 - 0.00051 18.5 0.1 0.00083 17.8 0.0 1.2 1 0 0 1 1 1 1 Baculovirus Y142 protein Mis14 PF08641.7 OAJ31768.1 - 0.0011 19.0 1.2 0.0011 19.0 0.8 1.6 2 0 0 2 2 2 1 Kinetochore protein Mis14 like Sec63 PF02889.11 OAJ31769.1 - 2.3e-180 598.6 0.0 5.5e-97 324.7 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 OAJ31769.1 - 1.4e-45 154.8 0.0 1.5e-27 96.1 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 OAJ31769.1 - 2.7e-12 46.9 0.0 1.4e-09 38.0 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 OAJ31769.1 - 1.2e-11 44.2 0.0 9.5e-09 35.0 0.0 3.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 OAJ31769.1 - 7e-05 22.9 0.0 0.0035 17.4 0.0 3.2 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 OAJ31769.1 - 0.027 13.6 0.0 0.78 8.9 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein Actin PF00022.14 OAJ31770.1 - 1.8e-132 441.5 0.0 2e-132 441.3 0.0 1.0 1 0 0 1 1 1 1 Actin HEAT PF02985.17 OAJ31771.1 - 0.00022 21.0 8.9 1.4 9.1 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 OAJ31771.1 - 0.00029 21.0 6.0 0.033 14.4 0.0 5.0 3 2 2 5 5 5 2 HEAT repeats Het-C PF07217.6 OAJ31771.1 - 0.018 13.2 0.1 0.039 12.1 0.0 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C HEAT_EZ PF13513.1 OAJ31771.1 - 3.3 8.3 10.8 64 4.2 0.0 5.7 5 0 0 5 5 5 0 HEAT-like repeat PHD PF00628.24 OAJ31772.1 - 4.5e-07 29.4 13.8 7.9e-07 28.6 9.5 1.4 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 OAJ31772.1 - 0.0069 16.7 0.0 0.0069 16.7 0.0 4.5 3 2 0 3 3 3 1 SET domain ANF_receptor PF01094.23 OAJ31772.1 - 0.17 10.6 0.1 0.39 9.4 0.0 1.5 2 0 0 2 2 2 0 Receptor family ligand binding region PHD_2 PF13831.1 OAJ31772.1 - 0.35 10.2 5.0 0.61 9.4 3.5 1.3 1 0 0 1 1 1 0 PHD-finger Pkinase PF00069.20 OAJ31773.1 - 7.4e-67 225.2 0.0 1.8e-66 223.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ31773.1 - 4.2e-50 170.2 0.0 6.8e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ31773.1 - 0.018 14.0 1.1 0.034 13.1 0.0 1.9 2 0 0 2 2 2 0 Kinase-like PAT1 PF09770.4 OAJ31773.1 - 2.3 6.3 18.6 3.5 5.7 12.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2422 PF10337.4 OAJ31773.1 - 8.1 5.1 8.9 13 4.4 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) UQ_con PF00179.21 OAJ31774.1 - 7.2e-47 158.3 0.0 8.4e-47 158.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ31774.1 - 4.2e-05 23.3 0.0 5.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 OAJ31774.1 - 0.016 14.8 0.1 0.033 13.8 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 OAJ31774.1 - 0.14 12.0 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain IBN_N PF03810.14 OAJ31775.1 - 4.9e-06 26.3 0.0 3.9e-05 23.4 0.0 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Ribosomal_L38e PF01781.13 OAJ31776.1 - 2e-31 107.5 0.4 2.5e-31 107.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF2344 PF10105.4 OAJ31776.1 - 0.072 12.5 0.2 0.29 10.5 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) zf-H2C2_2 PF13465.1 OAJ31777.1 - 2.9e-25 87.2 33.0 8.4e-08 32.1 0.4 6.6 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ31777.1 - 2.9e-19 68.1 42.4 0.0003 20.9 0.1 8.1 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ31777.1 - 6.6e-11 41.7 49.1 0.0012 18.9 1.0 8.4 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAJ31777.1 - 0.011 15.8 10.0 0.27 11.4 0.2 5.2 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 OAJ31777.1 - 0.026 14.4 23.5 0.047 13.6 0.3 5.5 6 1 0 6 6 6 0 C2H2-type zinc finger zf-met PF12874.2 OAJ31777.1 - 0.038 14.1 0.6 0.038 14.1 0.4 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DZR PF12773.2 OAJ31778.1 - 0.17 11.7 1.0 5.6 6.8 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-4CXXC_R1 PF10497.4 OAJ31778.1 - 0.22 11.6 1.5 0.28 11.3 1.1 1.2 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 ABC1 PF03109.11 OAJ31779.1 - 8.2e-25 87.0 0.1 1.4e-24 86.3 0.1 1.4 1 0 0 1 1 1 1 ABC1 family MBOAT PF03062.14 OAJ31780.1 - 4.4e-49 167.3 21.6 4.4e-49 167.3 14.9 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Ribosomal_S11 PF00411.14 OAJ31781.1 - 6.2e-39 132.5 0.3 8e-39 132.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 RFX_DNA_binding PF02257.10 OAJ31783.1 - 3.2e-22 78.4 0.2 7.2e-22 77.3 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain RRM_1 PF00076.17 OAJ31784.1 - 1.6e-32 110.9 0.9 3.8e-20 71.2 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ31784.1 - 1e-24 86.2 0.1 1.3e-14 53.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ31784.1 - 3.9e-10 39.4 0.0 1.7e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 OAJ31784.1 - 0.00064 19.4 0.0 0.31 10.7 0.0 2.4 2 0 0 2 2 2 2 Limkain b1 Calcipressin PF04847.7 OAJ31784.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Calcipressin DUF221 PF02714.10 OAJ31784.1 - 0.24 10.2 0.0 0.32 9.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF221 Tho2 PF11262.3 OAJ31785.1 - 1.9e-56 191.3 0.1 1.9e-56 191.3 0.1 2.8 2 1 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 OAJ31785.1 - 5e-21 74.2 0.1 1.2e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit DUF1777 PF08648.7 OAJ31785.1 - 5.9e-05 22.8 30.7 5.9e-05 22.8 21.3 8.7 7 2 1 8 8 8 1 Protein of unknown function (DUF1777) RNase_H2-Ydr279 PF09468.5 OAJ31785.1 - 0.58 9.3 5.2 0.81 8.8 1.2 2.7 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Rad1 PF02144.11 OAJ31786.1 - 8.1e-67 224.8 0.0 1.1e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 OAJ31786.1 - 0.11 11.5 0.1 9.4 5.2 0.0 2.2 1 1 1 2 2 2 0 Rad9 CsbD PF05532.7 OAJ31787.1 - 7.7e-06 25.4 20.6 0.0032 17.1 4.7 2.9 1 1 1 2 2 2 2 CsbD-like DUF1804 PF08822.6 OAJ31789.1 - 0.07 12.8 0.0 0.33 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) DUF3025 PF11227.3 OAJ31789.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) GHMP_kinases_N PF00288.21 OAJ31790.1 - 7e-08 32.4 1.2 2.6e-07 30.5 0.8 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain NAP PF00956.13 OAJ31791.1 - 4.4e-85 284.6 5.9 4.4e-85 284.6 4.1 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Kelch_4 PF13418.1 OAJ31792.1 - 1.1e-24 85.8 1.8 6.5e-08 32.2 0.0 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 OAJ31792.1 - 7e-21 73.8 6.7 8.4e-05 22.6 0.1 7.0 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.1 OAJ31792.1 - 1.8e-13 50.0 0.0 0.00062 19.8 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 OAJ31792.1 - 4.3e-13 48.5 0.0 1.5e-06 27.6 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 OAJ31792.1 - 8e-13 48.0 0.0 0.0071 16.2 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 OAJ31792.1 - 4.6e-05 23.0 1.0 0.2 11.5 0.0 3.9 4 0 0 4 4 4 2 Kelch motif PQQ_3 PF13570.1 OAJ31792.1 - 0.014 15.6 0.0 0.09 13.0 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain G-alpha PF00503.15 OAJ31793.1 - 1.5e-114 382.6 0.1 1.9e-114 382.4 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 OAJ31793.1 - 2.8e-12 46.2 0.2 2.3e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 OAJ31793.1 - 0.00065 20.1 0.0 1.1 9.8 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 OAJ31793.1 - 0.012 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 OAJ31793.1 - 0.014 14.8 0.1 0.037 13.4 0.0 1.7 1 1 1 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 OAJ31793.1 - 0.017 15.0 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 OAJ31793.1 - 0.032 13.3 0.2 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region CPT PF07931.7 OAJ31793.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF1212 PF06738.7 OAJ31794.1 - 3.4e-33 114.7 14.7 1.4e-32 112.7 1.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 OAJ31794.1 - 8e-19 67.8 11.6 8e-19 67.8 8.1 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3815) EcsB PF05975.7 OAJ31794.1 - 2.4 6.5 8.7 0.24 9.8 1.9 2.0 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB MCM PF00493.18 OAJ31795.1 - 2e-133 444.3 0.0 3.1e-133 443.6 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 OAJ31795.1 - 1.6e-22 80.2 0.0 9.3e-22 77.7 0.0 2.3 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 OAJ31795.1 - 3.8e-08 33.1 0.0 1e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 OAJ31795.1 - 3.9e-07 29.4 0.0 0.00016 20.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 OAJ31795.1 - 0.00014 21.5 0.0 0.0024 17.4 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAJ31795.1 - 0.0076 15.7 0.0 0.7 9.3 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_32 PF13654.1 OAJ31795.1 - 0.12 11.0 0.2 0.24 10.0 0.2 1.4 1 0 0 1 1 1 0 AAA domain HSP90 PF00183.13 OAJ31796.1 - 1.6e-128 429.4 21.7 2.2e-128 428.9 15.1 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 OAJ31796.1 - 1.7e-11 43.8 0.0 3.3e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAJ31796.1 - 2.4e-11 43.4 0.1 2.4e-11 43.4 0.1 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF45 PF01863.12 OAJ31796.1 - 0.62 9.8 8.9 1.3 8.7 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF45 CDC45 PF02724.9 OAJ31796.1 - 2.2 6.2 8.8 3.3 5.6 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein RNase_PH PF01138.16 OAJ31797.1 - 1.3e-33 116.1 0.1 1.8e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 OAJ31797.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 HSP90 PF00183.13 OAJ31798.1 - 1.3e-98 330.7 0.2 1.4e-98 330.6 0.2 1.0 1 0 0 1 1 1 1 Hsp90 protein HBS1_N PF08938.5 OAJ31798.1 - 0.058 13.5 0.2 0.14 12.2 0.2 1.7 1 0 0 1 1 1 0 HBS1 N-terminus DUF399 PF04187.8 OAJ31798.1 - 0.069 12.6 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF399 Ubiq-assoc PF09145.5 OAJ31798.1 - 0.07 13.0 0.1 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-associated SUV3_C PF12513.3 OAJ31799.1 - 5.8e-15 54.4 0.2 1.2e-14 53.4 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 OAJ31799.1 - 9.1e-11 41.4 0.0 1.9e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2834 PF11196.3 OAJ31800.1 - 0.034 14.2 3.4 0.89 9.7 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2834) YIF1 PF03878.10 OAJ31801.1 - 2.7e-72 242.7 0.0 3.7e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 YIF1 Ribosomal_L11_N PF03946.9 OAJ31801.1 - 0.54 9.7 8.8 0.029 13.8 2.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain Yip1 PF04893.12 OAJ31801.1 - 0.71 9.3 17.5 0.041 13.3 6.0 2.3 1 1 0 2 2 2 0 Yip1 domain SKN1 PF03935.10 OAJ31802.1 - 2.5e-153 510.8 0.1 3.9e-153 510.2 0.1 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) zf-C3HC4_2 PF13923.1 OAJ31803.1 - 2.5e-11 43.3 9.6 2.5e-11 43.3 6.6 3.1 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ31803.1 - 2.3e-09 36.9 9.3 2.3e-09 36.9 6.4 3.0 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAJ31803.1 - 4.2e-08 32.7 6.6 4.2e-08 32.7 4.6 3.2 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ31803.1 - 8e-08 31.8 6.3 8e-08 31.8 4.4 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 OAJ31803.1 - 8.4e-08 31.7 9.0 8.4e-08 31.7 6.2 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAJ31803.1 - 1.3e-05 24.8 5.2 2.9e-05 23.6 3.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 OAJ31803.1 - 2.8e-05 23.7 2.3 2.8e-05 23.7 1.6 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 OAJ31803.1 - 0.00052 19.8 9.2 0.00052 19.8 6.3 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 OAJ31803.1 - 0.0006 19.8 3.6 0.002 18.1 2.5 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger U-box PF04564.10 OAJ31803.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 U-box domain Prok-RING_4 PF14447.1 OAJ31803.1 - 0.055 13.0 4.0 0.16 11.5 2.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-P11 PF03854.9 OAJ31803.1 - 2.9 7.4 11.1 0.97 8.9 4.4 2.6 2 1 1 3 3 3 0 P-11 zinc finger UQ_con PF00179.21 OAJ31804.1 - 3.8e-45 152.7 0.0 4.7e-45 152.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ31804.1 - 0.012 15.3 0.0 0.049 13.3 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B HMG_box PF00505.14 OAJ31805.1 - 1.8e-20 72.9 0.8 1.8e-20 72.9 0.5 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ31805.1 - 1.3e-13 51.0 1.1 1.3e-13 51.0 0.7 1.9 1 1 1 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 OAJ31805.1 - 0.49 10.2 9.5 0.2 11.4 4.3 2.0 1 1 0 1 1 1 0 HMG (high mobility group) box 5 Mus7 PF09462.5 OAJ31806.1 - 3e-107 360.0 0.0 4.1e-107 359.5 0.0 1.1 1 0 0 1 1 1 1 Mus7/MMS22 family MMS22L_N PF14910.1 OAJ31806.1 - 0.0038 15.5 0.0 0.0071 14.6 0.0 1.3 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, N-terminal DUF3128 PF11326.3 OAJ31808.1 - 5.8e-19 68.0 1.1 1.1e-18 67.0 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DSPc PF00782.15 OAJ31808.1 - 2.9e-11 43.0 0.0 4.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAJ31808.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Robl_LC7 PF03259.12 OAJ31810.1 - 3.5e-06 26.4 0.0 6.5e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 Roadblock/LC7 domain TBCA PF02970.11 OAJ31811.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor A zf-CCHC PF00098.18 OAJ31812.1 - 1.6e-09 37.2 13.7 9e-05 22.2 1.3 2.7 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 OAJ31812.1 - 1.5e-07 30.9 0.3 2.8e-07 30.0 0.2 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 OAJ31812.1 - 1.1e-06 28.2 10.5 0.00017 21.2 2.4 2.4 1 1 1 2 2 2 2 Zinc knuckle DUF1897 PF09005.5 OAJ31812.1 - 4.2e-06 26.1 20.0 0.00011 21.6 2.7 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF1897) KH_3 PF13014.1 OAJ31812.1 - 0.00025 20.6 0.1 0.00057 19.4 0.1 1.7 1 0 0 1 1 1 1 KH domain DUF4609 PF15382.1 OAJ31812.1 - 0.16 11.6 0.4 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) zf-CCHC_4 PF14392.1 OAJ31812.1 - 0.17 11.5 9.3 1.1 9.0 0.8 2.3 2 0 0 2 2 2 0 Zinc knuckle adh_short PF00106.20 OAJ31813.1 - 4.7e-25 88.4 2.2 8.5e-24 84.3 1.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ31813.1 - 3.9e-20 72.6 0.3 2e-19 70.3 0.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ31813.1 - 5.5e-09 35.9 2.6 1.5e-08 34.5 0.4 2.3 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 OAJ31813.1 - 0.0003 20.3 1.0 0.0048 16.3 0.7 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 OAJ31813.1 - 0.0031 17.6 1.3 0.014 15.4 0.9 2.1 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 OAJ31813.1 - 0.0085 16.1 0.4 0.02 14.8 0.2 1.7 2 0 0 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 OAJ31813.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 OAJ31813.1 - 0.084 11.7 0.1 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YjeF_N PF03853.10 OAJ31813.1 - 0.088 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus RNase_P_Rpp14 PF01900.14 OAJ31813.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Rpp14/Pop5 family NPR3 PF03666.8 OAJ31814.1 - 3.8e-71 239.9 5.0 4.2e-40 137.6 0.0 3.5 3 0 0 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 OAJ31814.1 - 0.16 10.6 0.0 3.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Nitrogen permease regulator 2 PTPLA PF04387.9 OAJ31815.1 - 4.4e-48 162.8 5.1 4.4e-48 162.8 3.5 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA FAD-oxidase_C PF02913.14 OAJ31817.1 - 6e-51 173.1 0.0 1.2e-50 172.1 0.0 1.5 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 OAJ31817.1 - 3.1e-26 91.5 0.0 2e-25 88.8 0.0 2.4 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.7 OAJ31817.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like DHHW PF14286.1 OAJ31818.1 - 0.2 10.9 1.3 0.6 9.3 0.5 1.8 2 0 0 2 2 2 0 DHHW protein DUF1168 PF06658.7 OAJ31818.1 - 2.2 7.8 9.1 0.13 11.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) RAP1 PF07218.6 OAJ31818.1 - 6.1 4.8 13.3 6.5 4.7 9.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Acyl-thio_N PF12590.3 OAJ31818.1 - 8.1 6.9 10.3 0.083 13.3 1.3 1.9 3 0 0 3 3 3 0 Acyl-ATP thioesterase NCA2 PF08637.5 OAJ31819.1 - 1.7e-72 243.8 0.0 3.4e-72 242.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Nrap PF03813.9 OAJ31820.1 - 8.9e-235 781.5 0.0 1.1e-234 781.2 0.0 1.0 1 0 0 1 1 1 1 Nrap protein Nop14 PF04147.7 OAJ31820.1 - 0.0011 16.9 23.3 0.0017 16.4 16.1 1.1 1 0 0 1 1 1 1 Nop14-like family DUF2890 PF11081.3 OAJ31820.1 - 0.16 12.0 10.0 0.4 10.7 6.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 OAJ31820.1 - 1.1 7.6 23.4 1.7 7.0 16.2 1.2 1 0 0 1 1 1 0 Daxx Family eIF3_subunit PF08597.5 OAJ31820.1 - 1.4 8.4 21.2 1 8.8 5.9 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit SDA1 PF05285.7 OAJ31820.1 - 7.8 5.6 24.0 14 4.8 16.6 1.3 1 0 0 1 1 1 0 SDA1 Ribosomal_L18e PF00828.14 OAJ31821.1 - 2.7e-20 73.0 0.0 4.2e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DUF1649 PF07855.7 OAJ31822.1 - 3.7e-15 55.9 0.0 3.1e-14 52.9 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1649) ABC_membrane PF00664.18 OAJ31826.1 - 3.4e-58 197.2 21.3 2.7e-32 112.2 6.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ31826.1 - 2.3e-50 170.4 0.0 4.5e-26 91.7 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 OAJ31826.1 - 4.1e-07 29.4 0.1 0.016 14.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 OAJ31826.1 - 3.2e-06 27.6 0.1 0.15 12.5 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_21 PF13304.1 OAJ31826.1 - 5e-06 26.6 0.0 0.76 9.6 0.0 4.2 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 OAJ31826.1 - 6.4e-06 26.1 0.0 0.15 11.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 OAJ31826.1 - 7.1e-06 25.5 0.1 0.019 14.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 OAJ31826.1 - 8.2e-06 25.2 1.5 0.55 9.4 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 OAJ31826.1 - 6.8e-05 22.9 1.8 0.15 11.9 0.0 3.6 3 1 1 4 4 4 2 AAA ATPase domain DUF258 PF03193.11 OAJ31826.1 - 0.00067 18.8 0.6 0.27 10.4 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 OAJ31826.1 - 0.0022 18.3 7.2 0.088 13.1 0.0 3.6 4 0 0 4 4 3 1 AAA domain Dynamin_N PF00350.18 OAJ31826.1 - 0.0031 17.3 4.3 0.43 10.3 0.0 3.1 3 0 0 3 3 2 2 Dynamin family AAA_17 PF13207.1 OAJ31826.1 - 0.0031 18.2 0.0 2.6 8.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 OAJ31826.1 - 0.0048 16.0 1.4 0.52 9.3 0.3 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 OAJ31826.1 - 0.0085 16.3 0.4 3.5 7.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 OAJ31826.1 - 0.017 14.7 0.1 7.9 6.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 OAJ31826.1 - 0.03 13.7 0.1 3.6 6.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.1 OAJ31826.1 - 0.12 11.3 3.0 0.31 10.0 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain Arch_ATPase PF01637.13 OAJ31826.1 - 0.32 10.6 0.0 0.32 10.6 0.0 2.9 4 0 0 4 4 2 0 Archaeal ATPase ZZ PF00569.12 OAJ31827.1 - 2.7e-09 36.4 64.6 2e-05 23.9 1.8 6.6 6 1 0 6 6 6 4 Zinc finger, ZZ type PB1 PF00564.19 OAJ31827.1 - 1.1e-05 25.0 0.1 2.3e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 PB1 domain dsDNA_bind PF01984.15 OAJ31828.1 - 3.1e-26 91.4 11.7 2e-25 88.8 8.1 1.9 1 1 0 1 1 1 1 Double-stranded DNA-binding domain TilS PF09179.6 OAJ31828.1 - 0.89 9.6 3.2 0.96 9.5 0.8 2.0 2 0 0 2 2 2 0 TilS substrate binding domain Pkinase PF00069.20 OAJ31829.1 - 1.8e-67 227.2 0.0 3.1e-67 226.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ31829.1 - 4.6e-48 163.5 0.0 7.9e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ31829.1 - 7.8e-05 21.7 0.0 0.00024 20.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAJ31829.1 - 0.046 13.4 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family RTTN_N PF14726.1 OAJ31829.1 - 0.15 12.6 1.8 1.7 9.2 0.1 2.8 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning Trp_DMAT PF11991.3 OAJ31830.1 - 5.4e-57 193.6 0.1 7.5e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase ThiF PF00899.16 OAJ31831.1 - 1.5e-15 57.2 0.0 2.5e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 ThiF family 2-oxoacid_dh PF00198.18 OAJ31832.1 - 1.4e-79 266.6 0.1 1.9e-79 266.2 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 OAJ31832.1 - 1.2e-20 72.8 5.0 1.3e-20 72.7 2.1 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 OAJ31832.1 - 2.6e-17 62.1 0.1 5.7e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 OAJ31832.1 - 5.9e-05 22.6 1.9 0.24 11.1 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like DNA_alkylation PF08713.6 OAJ31832.1 - 0.057 12.9 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 DNA alkylation repair enzyme RR_TM4-6 PF06459.7 OAJ31832.1 - 1.5 8.6 5.0 2.9 7.7 3.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.9 OAJ31832.1 - 3.7 7.1 5.5 1 9.0 1.5 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) ELL PF10390.4 OAJ31832.1 - 4.9 6.2 9.4 16 4.6 6.5 1.8 1 1 0 1 1 1 0 RNA polymerase II elongation factor ELL PIG-S PF10510.4 OAJ31834.1 - 3.8e-107 359.1 0.0 5.6e-107 358.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Myosin_head PF00063.16 OAJ31835.1 - 2.7e-243 809.0 0.6 2.7e-243 809.0 0.4 1.9 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 OAJ31835.1 - 1e-34 118.5 1.8 1e-34 118.5 1.2 2.4 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 OAJ31835.1 - 5.9e-07 28.5 32.5 0.18 11.5 0.2 7.0 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 OAJ31835.1 - 0.0016 18.5 0.2 0.0094 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain TPR_MLP1_2 PF07926.7 OAJ31835.1 - 0.0022 17.7 6.0 0.0022 17.7 4.1 2.7 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein DivIC PF04977.10 OAJ31835.1 - 0.0028 17.0 6.2 0.0028 17.0 4.3 3.1 2 1 0 2 2 2 1 Septum formation initiator AAA_19 PF13245.1 OAJ31835.1 - 0.046 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 OAJ31835.1 - 0.24 10.5 5.0 1.2 8.2 0.2 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Dynactin PF12455.3 OAJ31837.1 - 2.1e-50 171.1 1.0 2.1e-50 171.1 0.7 3.7 4 0 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 OAJ31837.1 - 4.5e-19 67.9 1.1 8.7e-19 67.0 0.8 1.5 1 0 0 1 1 1 1 CAP-Gly domain DUF4407 PF14362.1 OAJ31837.1 - 0.00069 18.6 8.6 0.00069 18.6 6.0 5.4 3 1 2 5 5 5 1 Domain of unknown function (DUF4407) GAS PF13851.1 OAJ31837.1 - 0.0088 15.2 75.4 0.025 13.7 11.6 4.7 3 1 1 4 4 4 4 Growth-arrest specific micro-tubule binding Pyr_redox_3 PF13738.1 OAJ31840.1 - 7.2e-25 88.2 0.0 1.1e-24 87.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ31840.1 - 6.8e-05 21.9 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAJ31840.1 - 7e-05 22.7 0.0 0.00069 19.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ31840.1 - 0.0024 17.6 0.3 0.25 11.1 0.1 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.17 OAJ31840.1 - 0.011 14.6 0.3 0.02 13.8 0.2 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 OAJ31840.1 - 0.07 12.1 0.3 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 OAJ31840.1 - 0.12 10.7 3.5 0.46 8.8 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.16 OAJ31840.1 - 0.16 11.5 0.1 0.3 10.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SNARE PF05739.14 OAJ31841.1 - 1e-10 41.1 2.1 1e-10 41.1 1.4 2.0 2 0 0 2 2 2 1 SNARE domain FliJ PF02050.11 OAJ31841.1 - 0.052 13.5 2.9 0.19 11.7 0.7 2.4 3 0 0 3 3 3 0 Flagellar FliJ protein YjcZ PF13990.1 OAJ31841.1 - 0.084 11.9 2.9 0.13 11.4 0.6 1.9 2 0 0 2 2 2 0 YjcZ-like protein SlyX PF04102.7 OAJ31841.1 - 3.2 8.1 8.8 1.8 8.9 2.0 3.4 3 2 0 3 3 3 0 SlyX Ribosomal_S18 PF01084.15 OAJ31842.1 - 1e-17 63.7 0.0 1.7e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 EMP24_GP25L PF01105.19 OAJ31843.1 - 7.1e-43 146.4 0.0 9.4e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Zn_clus PF00172.13 OAJ31844.1 - 6.6e-05 22.7 6.3 0.00011 22.0 4.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain P34-Arc PF04045.9 OAJ31846.1 - 1.2e-104 348.8 0.1 2.6e-104 347.8 0.0 1.5 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc XRN_N PF03159.13 OAJ31846.1 - 1.6e-87 292.8 0.0 3.1e-87 291.8 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DNA_pol_A PF00476.15 OAJ31848.1 - 9e-89 297.7 0.0 3e-88 296.0 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase family A Glyco_hydro_3 PF00933.16 OAJ31849.1 - 2.6e-84 282.7 0.0 4.1e-84 282.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 OAJ31849.1 - 7.8e-57 192.4 2.5 1.5e-56 191.4 0.4 2.3 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 OAJ31849.1 - 9.3e-19 67.1 0.0 1.9e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF1768 PF08719.6 OAJ31850.1 - 9.4e-24 83.9 0.0 1.4e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) UCH PF00443.24 OAJ31851.1 - 2.9e-41 141.3 0.0 3.7e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ31851.1 - 6.5e-12 45.4 0.0 3.8e-05 23.2 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Lambda_CIII PF02061.11 OAJ31852.1 - 0.1 12.6 0.1 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Lambda Phage CIII PARP PF00644.15 OAJ31853.1 - 0.023 14.0 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain E_Pc_C PF06752.7 OAJ31854.1 - 0.32 10.4 4.1 0.41 10.1 2.8 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus SSP160 PF06933.6 OAJ31854.1 - 2.4 6.0 5.9 2.8 5.8 4.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HlyIII PF03006.15 OAJ31857.1 - 9.5e-56 188.6 19.7 1.4e-55 188.1 13.6 1.3 1 0 0 1 1 1 1 Haemolysin-III related UPF0060 PF02694.10 OAJ31857.1 - 0.064 13.2 3.3 0.063 13.2 0.6 2.2 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family SMC_N PF02463.14 OAJ31859.1 - 1.3e-68 230.5 1.3 1.9e-68 229.9 0.9 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 OAJ31859.1 - 5.4e-31 107.0 0.2 2.1e-30 105.1 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 OAJ31859.1 - 3e-14 53.6 8.0 2.4e-06 27.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 OAJ31859.1 - 4.3e-14 53.3 30.7 4.3e-14 53.3 21.3 6.9 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.1 OAJ31859.1 - 0.0028 17.1 0.0 0.0075 15.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 OAJ31859.1 - 0.19 12.0 19.9 0.54 10.5 0.0 5.2 3 2 0 4 4 4 0 ABC transporter FtsK_SpoIIIE PF01580.13 OAJ31859.1 - 0.34 10.3 0.0 0.34 10.3 0.0 4.6 6 0 0 6 6 6 0 FtsK/SpoIIIE family HMA PF00403.21 OAJ31859.1 - 0.53 10.4 3.7 0.3 11.2 0.1 2.6 3 0 0 3 3 3 0 Heavy-metal-associated domain Mmp37 PF09139.6 OAJ31861.1 - 5.1e-99 331.4 0.0 9.7e-99 330.4 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial matrix Mmp37 FGGY_C PF02782.11 OAJ31863.1 - 1.7e-43 148.5 0.1 2.6e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 OAJ31863.1 - 7.3e-24 84.4 0.0 6.3e-23 81.3 0.0 2.4 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 OAJ31863.1 - 5.3e-06 25.9 0.3 2.3e-05 23.8 0.1 1.9 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.16 OAJ31863.1 - 0.0093 15.3 0.0 0.032 13.5 0.0 1.8 2 0 0 2 2 2 1 Hexokinase DUF4445 PF14574.1 OAJ31863.1 - 0.16 10.1 0.1 4.3 5.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4445) SNF2_N PF00176.18 OAJ31864.1 - 1.3e-59 201.4 0.0 3.7e-30 104.7 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ31864.1 - 6.7e-10 38.6 0.0 2e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 OAJ31864.1 - 3.8e-09 36.4 6.1 7.4e-09 35.4 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ31864.1 - 3.9e-09 36.0 5.3 7.6e-09 35.0 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ31864.1 - 1.8e-08 34.0 4.7 3.4e-08 33.1 3.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 OAJ31864.1 - 2e-06 27.5 8.0 4.8e-06 26.3 5.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 OAJ31864.1 - 2.9e-06 26.8 2.3 5.8e-06 25.8 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ31864.1 - 2e-05 24.2 3.1 4.2e-05 23.1 2.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ31864.1 - 0.00015 21.4 4.1 0.00035 20.2 2.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 OAJ31864.1 - 0.012 15.7 1.9 0.036 14.1 1.3 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger DUF2019 PF09450.5 OAJ31864.1 - 0.039 13.8 0.2 0.099 12.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) zf-RING_6 PF14835.1 OAJ31864.1 - 0.056 13.2 1.9 0.12 12.2 1.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein RNase_PH PF01138.16 OAJ31865.1 - 5.1e-16 59.1 0.0 1.3e-15 57.9 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 OAJ31865.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 QueF_N PF14819.1 OAJ31867.1 - 0.095 12.7 0.3 7.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term Pox_Ag35 PF03286.9 OAJ31867.1 - 0.15 11.5 2.4 0.42 10.1 1.7 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF605 PF04652.11 OAJ31868.1 - 0.51 9.6 39.9 0.24 10.7 23.2 2.1 2 0 0 2 2 2 0 Vta1 like DUF3405 PF11885.3 OAJ31869.1 - 1.5e-136 455.5 0.4 3e-128 428.2 1.2 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF3405) Pex14_N PF04695.8 OAJ31869.1 - 1.7 8.7 4.9 1.5 8.8 0.0 2.7 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Aldo_ket_red PF00248.16 OAJ31870.1 - 1.2e-09 37.3 0.0 1.3e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Vezatin PF12632.2 OAJ31871.1 - 0.002 17.2 0.0 0.0066 15.5 0.0 1.8 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes FF PF01846.14 OAJ31872.1 - 3.9e-19 68.3 8.9 1.6e-08 34.3 0.0 5.3 5 1 0 5 5 5 2 FF domain WW PF00397.21 OAJ31872.1 - 2.5e-12 46.4 14.1 1.3e-06 28.1 1.7 2.7 2 0 0 2 2 2 2 WW domain Sugar_tr PF00083.19 OAJ31873.1 - 1.2e-103 347.1 15.3 1.4e-103 346.9 10.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ31873.1 - 9.4e-28 96.9 23.5 9.4e-28 96.9 16.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 OAJ31873.1 - 5.9e-06 24.9 16.4 0.00079 17.9 1.6 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein DUF3180 PF11377.3 OAJ31873.1 - 0.07 12.9 0.3 0.07 12.9 0.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3180) MFS_3 PF05977.8 OAJ31873.1 - 0.095 10.7 2.3 0.15 10.1 0.2 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector Ribosomal_S11 PF00411.14 OAJ31874.1 - 2.6e-10 40.4 3.4 3.6e-06 27.1 0.0 2.8 3 0 0 3 3 3 2 Ribosomal protein S11 Amidohydro_1 PF01979.15 OAJ31875.1 - 1.2e-59 202.6 0.6 2e-59 201.9 0.4 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 OAJ31875.1 - 2.9e-57 192.0 0.7 8.7e-57 190.5 0.5 1.9 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.13 OAJ31875.1 - 5.2e-41 138.6 0.2 1.2e-40 137.4 0.1 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.15 OAJ31875.1 - 1.4e-35 121.0 0.0 5.8e-35 119.1 0.0 1.9 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_5 PF13594.1 OAJ31875.1 - 6.6e-06 25.8 6.3 1.4e-05 24.8 2.5 2.8 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 OAJ31875.1 - 3.5e-05 23.2 1.9 4.2e-05 22.9 0.1 1.8 1 1 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 OAJ31875.1 - 0.0037 17.3 0.0 2.8 7.8 0.0 2.8 2 0 0 2 2 2 2 Amidohydrolase MT-A70 PF05063.9 OAJ31876.1 - 8.2e-37 126.4 0.2 6.8e-26 90.8 0.0 3.2 3 0 0 3 3 3 3 MT-A70 BAF1_ABF1 PF04684.8 OAJ31876.1 - 4.3 6.0 8.2 8.5 5.0 5.7 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF947 PF06102.7 OAJ31877.1 - 6.2e-31 107.4 9.1 6.2e-31 107.4 6.3 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF947) Aldo_ket_red PF00248.16 OAJ31878.1 - 8.9e-27 93.6 0.0 8.7e-13 47.7 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family AAA PF00004.24 OAJ31879.1 - 1.3e-47 161.2 0.0 2.2e-43 147.6 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 OAJ31879.1 - 3.6e-20 71.7 0.0 8.3e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_17 PF13207.1 OAJ31879.1 - 1.1e-07 32.7 0.1 0.013 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAJ31879.1 - 5.7e-07 29.6 11.9 0.0082 16.1 1.3 4.7 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 OAJ31879.1 - 1.1e-06 28.7 2.1 0.1 12.7 0.1 4.2 3 2 0 3 3 2 2 AAA domain AAA_18 PF13238.1 OAJ31879.1 - 8.7e-06 26.0 0.1 0.095 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 OAJ31879.1 - 8.9e-06 25.3 0.4 0.029 14.1 0.0 3.2 3 0 0 3 3 2 2 Part of AAA domain AAA_5 PF07728.9 OAJ31879.1 - 5.2e-05 23.0 0.1 0.38 10.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 OAJ31879.1 - 5.4e-05 23.0 0.0 0.066 13.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 OAJ31879.1 - 0.00036 19.9 0.2 0.93 8.8 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.7 OAJ31879.1 - 0.00044 19.3 0.0 0.003 16.6 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 OAJ31879.1 - 0.00044 19.9 0.4 5.6 6.6 0.0 4.3 4 0 0 4 4 4 0 NACHT domain RNA_helicase PF00910.17 OAJ31879.1 - 0.00057 20.0 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 OAJ31879.1 - 0.0006 19.0 0.2 0.84 8.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 OAJ31879.1 - 0.00074 18.5 0.0 0.25 10.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 OAJ31879.1 - 0.00078 19.4 0.2 1.2 9.1 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAJ31879.1 - 0.0012 18.2 2.9 3.9 6.8 0.0 4.2 3 1 1 4 4 4 1 AAA domain AAA_14 PF13173.1 OAJ31879.1 - 0.008 16.0 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 OAJ31879.1 - 0.0081 15.8 0.0 0.16 11.6 0.0 2.7 2 1 1 3 3 3 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 OAJ31879.1 - 0.0087 15.1 0.2 1 8.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_2 PF07724.9 OAJ31879.1 - 0.0098 15.8 0.0 0.06 13.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 OAJ31879.1 - 0.011 14.5 0.2 0.14 10.8 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus Viral_helicase1 PF01443.13 OAJ31879.1 - 0.014 14.9 0.0 0.052 13.0 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 OAJ31879.1 - 0.023 13.8 0.3 3.4 6.7 0.1 2.4 2 0 0 2 2 2 0 KaiC SKI PF01202.17 OAJ31879.1 - 0.036 13.9 0.2 0.76 9.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 OAJ31879.1 - 0.045 13.3 0.2 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 OAJ31879.1 - 0.047 13.1 0.1 3.3 7.1 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain T2SE PF00437.15 OAJ31879.1 - 0.062 12.2 0.1 0.48 9.2 0.1 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Cytidylate_kin2 PF13189.1 OAJ31879.1 - 0.078 12.8 0.8 0.57 10.0 0.0 2.7 3 0 0 3 3 3 0 Cytidylate kinase-like family NB-ARC PF00931.17 OAJ31879.1 - 0.082 11.7 0.1 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_3 PF07726.6 OAJ31879.1 - 0.17 11.5 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Thiolase_N PF00108.18 OAJ31882.1 - 6.1e-83 277.8 4.9 6.1e-83 277.8 3.4 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAJ31882.1 - 7e-44 148.1 0.6 1.6e-43 147.0 0.4 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 OAJ31882.1 - 0.24 10.8 5.0 0.17 11.3 0.3 2.9 3 1 1 4 4 4 0 Beta-ketoacyl synthase, N-terminal domain Reprolysin_5 PF13688.1 OAJ31883.1 - 3e-45 154.5 5.2 3e-45 154.5 3.6 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 OAJ31883.1 - 1.1e-43 149.1 0.2 2.5e-43 148.0 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 OAJ31883.1 - 1.6e-39 135.7 3.7 1.8e-39 135.5 1.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 OAJ31883.1 - 4.6e-18 65.9 0.0 1.2e-17 64.6 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 OAJ31883.1 - 1.3e-13 50.9 22.4 1.3e-13 50.9 15.5 4.1 3 1 1 4 4 4 1 Disintegrin Reprolysin PF01421.14 OAJ31883.1 - 5.6e-09 35.8 2.8 2.5e-07 30.4 0.0 3.3 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 OAJ31883.1 - 3.3e-08 33.3 0.1 8e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M66 PF10462.4 OAJ31883.1 - 0.19 10.5 0.1 0.34 9.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 TB2_DP1_HVA22 PF03134.14 OAJ31884.1 - 1.5e-05 24.6 0.2 3.1e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Ank_4 PF13637.1 OAJ31886.1 - 1.5e-12 47.6 1.0 1e-06 29.1 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 OAJ31886.1 - 6e-11 42.5 0.0 1.1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ31886.1 - 4.8e-07 29.2 0.4 4.1e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 OAJ31886.1 - 5.2e-06 26.2 0.2 0.00059 19.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 OAJ31886.1 - 9.3e-06 25.7 0.6 4.1e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Methyltransf_18 PF12847.2 OAJ31886.1 - 9.5e-05 22.9 0.0 0.00044 20.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ31886.1 - 0.00043 20.7 0.0 0.00088 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 OAJ31886.1 - 0.0026 18.5 0.0 0.0088 16.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ31886.1 - 0.069 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ31886.1 - 0.12 12.4 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Pox_A_type_inc PF04508.7 OAJ31887.1 - 0.022 14.5 1.2 2 8.4 0.0 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat FAD-oxidase_C PF02913.14 OAJ31887.1 - 0.058 12.6 0.5 0.088 12.1 0.3 1.4 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Lebercilin PF15619.1 OAJ31887.1 - 0.54 9.6 6.7 0.38 10.1 2.4 2.3 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Myb_DNA-binding PF00249.26 OAJ31888.1 - 6.4e-11 42.1 0.9 1.4e-10 41.0 0.6 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ31888.1 - 6.5e-07 29.3 1.9 1.3e-06 28.4 0.6 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Histone PF00125.19 OAJ31890.1 - 8.6e-14 51.4 0.1 1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ31890.1 - 0.00012 22.2 0.0 0.00016 21.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 OAJ31890.1 - 0.00024 20.9 0.1 0.00034 20.4 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 OAJ31890.1 - 0.00077 19.4 0.1 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 OAJ31890.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Syntaxin PF00804.20 OAJ31891.1 - 5.2e-12 45.8 1.4 5.2e-12 45.8 1.0 2.5 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.14 OAJ31891.1 - 1.9e-08 33.8 12.5 3e-07 30.0 4.2 3.6 3 0 0 3 3 3 1 SNARE domain TPR_10 PF13374.1 OAJ31891.1 - 0.058 13.3 0.3 0.68 9.9 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec8_exocyst PF04048.9 OAJ31891.1 - 0.24 11.0 6.5 0.093 12.3 1.6 2.2 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF2721 PF11026.3 OAJ31891.1 - 0.25 10.9 3.8 12 5.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) TPR_16 PF13432.1 OAJ31891.1 - 0.79 10.4 4.3 1.2 9.9 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Herpes_US9 PF06072.6 OAJ31891.1 - 1 9.2 3.3 2.2 8.1 2.3 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Muted PF14942.1 OAJ31891.1 - 1.4 8.7 13.3 0.067 13.0 2.0 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein GRP PF07172.6 OAJ31891.1 - 2 8.9 13.2 17 5.9 8.2 2.7 2 0 0 2 2 2 0 Glycine rich protein family Syntaxin_2 PF14523.1 OAJ31891.1 - 3.1 7.8 11.5 0.31 11.0 2.5 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DUF3810 PF12725.2 OAJ31891.1 - 9.5 5.0 7.8 5.3 5.8 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Ran_BP1 PF00638.13 OAJ31892.1 - 7.9e-15 54.9 0.0 2e-07 31.0 0.0 2.3 2 0 0 2 2 2 2 RanBP1 domain Histone PF00125.19 OAJ31893.1 - 5.5e-29 100.1 1.1 8.4e-29 99.5 0.7 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ31893.1 - 4.7e-05 23.4 0.1 7.2e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAJ31893.1 - 0.0019 18.2 0.2 0.0037 17.2 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 OAJ31893.1 - 0.028 14.1 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated AAA PF00004.24 OAJ31896.1 - 4.7e-52 175.6 0.0 7.3e-39 132.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.12 OAJ31896.1 - 1.3e-09 37.5 0.1 2e-08 33.7 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.9 OAJ31896.1 - 2.7e-08 33.9 0.1 1.8e-05 24.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 OAJ31896.1 - 4e-07 30.8 0.0 0.0068 17.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAJ31896.1 - 7.6e-07 29.3 0.1 0.0012 19.0 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 OAJ31896.1 - 8.6e-07 28.9 0.0 0.012 15.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 OAJ31896.1 - 1e-06 27.9 0.3 0.024 13.7 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 OAJ31896.1 - 1.4e-06 27.3 0.1 0.042 12.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 OAJ31896.1 - 3.3e-06 27.0 0.0 0.062 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 OAJ31896.1 - 4e-06 27.1 0.1 0.0074 16.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 OAJ31896.1 - 4.7e-06 26.3 0.0 0.002 17.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 OAJ31896.1 - 7.6e-06 25.2 0.4 0.006 15.7 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 OAJ31896.1 - 1.2e-05 24.9 1.4 0.12 12.1 0.0 3.2 2 0 0 2 2 2 2 Part of AAA domain AAA_16 PF13191.1 OAJ31896.1 - 1.6e-05 25.0 0.1 0.12 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.12 OAJ31896.1 - 0.00014 21.3 0.5 0.031 13.7 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 OAJ31896.1 - 0.00015 21.8 0.0 0.097 12.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Parvo_NS1 PF01057.12 OAJ31896.1 - 0.00025 20.0 0.0 0.16 10.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 KTI12 PF08433.5 OAJ31896.1 - 0.00027 20.2 0.1 0.17 11.0 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_28 PF13521.1 OAJ31896.1 - 0.00028 20.8 0.0 0.79 9.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAJ31896.1 - 0.00034 20.0 0.5 0.58 9.5 0.0 3.2 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.7 OAJ31896.1 - 0.00038 19.6 0.1 0.66 9.0 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin CDC48_N PF02359.13 OAJ31896.1 - 0.00087 19.1 0.0 0.0033 17.3 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain ABC_tran PF00005.22 OAJ31896.1 - 0.0011 19.3 0.3 0.037 14.3 0.0 2.6 2 0 0 2 2 2 1 ABC transporter KaiC PF06745.8 OAJ31896.1 - 0.0015 17.6 0.6 0.011 14.8 0.1 2.2 2 0 0 2 2 2 1 KaiC Sigma54_activat PF00158.21 OAJ31896.1 - 0.0022 17.4 0.0 0.82 9.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 OAJ31896.1 - 0.0032 17.0 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 OAJ31896.1 - 0.004 16.7 0.2 0.32 10.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 OAJ31896.1 - 0.0046 16.6 0.1 0.045 13.3 0.0 2.2 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.1 OAJ31896.1 - 0.0059 16.1 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 OAJ31896.1 - 0.006 16.2 0.1 0.54 9.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 OAJ31896.1 - 0.0066 16.1 1.1 3.6 7.2 0.0 3.3 4 0 0 4 4 3 1 NACHT domain PhoH PF02562.11 OAJ31896.1 - 0.01 15.0 0.0 0.82 8.8 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein Arch_ATPase PF01637.13 OAJ31896.1 - 0.015 14.9 0.4 35 3.9 0.0 3.5 2 2 2 4 4 4 0 Archaeal ATPase AAA_30 PF13604.1 OAJ31896.1 - 0.023 14.2 0.1 0.89 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 OAJ31896.1 - 0.034 13.0 0.0 2.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 OAJ31896.1 - 0.066 13.2 0.0 12 5.9 0.0 3.3 3 1 0 3 3 2 0 Sigma-54 interaction domain IPT PF01745.11 OAJ31896.1 - 0.081 12.0 0.4 1.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Isopentenyl transferase DUF2075 PF09848.4 OAJ31896.1 - 0.12 11.3 0.0 0.73 8.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Homoserine_dh PF00742.14 OAJ31897.1 - 4.9e-46 156.6 0.0 7.1e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 OAJ31897.1 - 2.1e-14 53.9 0.0 4e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain SPX PF03105.14 OAJ31898.1 - 9.1 5.9 18.2 0.083 12.6 3.4 3.0 2 1 0 3 3 3 0 SPX domain Apc4 PF12896.2 OAJ31899.1 - 2.8e-21 75.7 0.0 5.6e-21 74.8 0.0 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Hexapep PF00132.19 OAJ31900.1 - 3.6e-10 38.8 10.7 9.6e-08 31.1 4.7 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 OAJ31900.1 - 4.2e-10 39.4 0.0 9.7e-10 38.3 0.0 1.6 1 1 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 OAJ31900.1 - 1.4e-07 30.9 8.9 2.5e-07 30.1 5.3 2.0 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase CytochromB561_N PF09786.4 OAJ31901.1 - 0.057 11.8 1.6 0.054 11.9 1.1 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal GMC_oxred_N PF00732.14 OAJ31902.1 - 6.9e-40 137.0 0.0 1.1e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ31902.1 - 3.1e-21 76.1 0.7 1.5e-19 70.7 0.5 2.9 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 OAJ31902.1 - 1e-08 34.5 0.9 3e-05 23.0 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 OAJ31902.1 - 2.2e-05 24.3 0.5 7.7e-05 22.6 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ31902.1 - 0.00012 21.1 2.4 0.00027 19.9 0.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAJ31902.1 - 0.00044 19.4 0.3 0.00067 18.8 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAJ31902.1 - 0.0014 18.5 0.8 0.0082 16.0 0.3 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ31902.1 - 0.009 15.1 0.2 0.016 14.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 OAJ31902.1 - 0.022 13.2 0.3 0.044 12.2 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 OAJ31902.1 - 0.033 13.1 0.1 0.054 12.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.2 OAJ31902.1 - 0.04 12.9 0.9 0.062 12.3 0.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 OAJ31902.1 - 0.12 11.7 0.6 0.22 10.9 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 OAJ31902.1 - 0.15 10.9 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Ammonium_transp PF00909.16 OAJ31903.1 - 2.2e-104 349.1 29.3 2.8e-104 348.7 20.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family YqzM PF14141.1 OAJ31903.1 - 0.042 13.6 0.2 0.15 11.8 0.1 1.9 1 0 0 1 1 1 0 YqzM-like protein YCII PF03795.9 OAJ31904.1 - 0.0057 16.8 0.0 0.02 15.0 0.0 1.9 1 0 0 1 1 1 1 YCII-related domain Serglycin PF04360.7 OAJ31904.1 - 0.54 9.9 18.1 5.4 6.7 11.8 2.4 2 1 1 3 3 3 0 Serglycin ER_lumen_recept PF00810.13 OAJ31905.1 - 1.3e-50 171.6 4.3 1.8e-50 171.2 3.0 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 OAJ31905.1 - 0.0048 16.4 0.8 0.0048 16.4 0.6 4.0 4 0 0 4 4 4 2 PQ loop repeat Mago_nashi PF02792.9 OAJ31906.1 - 3.3e-74 247.3 0.4 3.8e-74 247.1 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein NIF PF03031.13 OAJ31907.1 - 8e-49 165.3 0.0 2.3e-42 144.3 0.0 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Spt20 PF12090.3 OAJ31907.1 - 0.23 10.7 4.0 12 5.1 0.0 2.1 2 0 0 2 2 2 0 Spt20 family Mitofilin PF09731.4 OAJ31907.1 - 0.38 9.3 7.1 0.52 8.8 4.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FLO_LFY PF01698.11 OAJ31907.1 - 0.72 8.6 9.0 1 8.1 6.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Baculo_PP31 PF05311.6 OAJ31907.1 - 0.87 8.7 5.4 1.2 8.3 3.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Daxx PF03344.10 OAJ31907.1 - 4.5 5.6 20.7 5.9 5.2 14.4 1.1 1 0 0 1 1 1 0 Daxx Family ORC6 PF05460.8 OAJ31907.1 - 5.5 5.9 14.5 6.7 5.7 10.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FAM60A PF15396.1 OAJ31907.1 - 8.5 6.0 9.2 14 5.3 6.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF3449 PF11931.3 OAJ31908.1 - 1.6e-70 236.6 0.5 2.9e-69 232.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) zf-met PF12874.2 OAJ31908.1 - 8.4e-05 22.6 3.9 0.00091 19.3 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 OAJ31908.1 - 0.00093 19.2 7.7 0.0057 16.7 0.1 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 OAJ31908.1 - 0.0024 17.9 0.5 2.5 8.2 0.1 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) SF3a60_bindingd PF12108.3 OAJ31908.1 - 0.0064 16.0 0.8 0.027 13.9 0.0 2.2 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-C2H2 PF00096.21 OAJ31908.1 - 1 9.8 7.1 1.5 9.2 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2175 PF09943.4 OAJ31908.1 - 1.3 9.0 6.9 6 6.9 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) NOA36 PF06524.7 OAJ31908.1 - 1.9 7.6 4.4 2.9 7.0 0.1 2.3 2 0 0 2 2 2 0 NOA36 protein DEAD PF00270.24 OAJ31909.1 - 2.6e-42 144.2 0.5 5e-42 143.2 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ31909.1 - 1.6e-29 101.6 0.1 3.8e-29 100.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 OAJ31909.1 - 0.0051 16.5 0.2 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 OAJ31909.1 - 0.019 14.7 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1253 PF06862.7 OAJ31909.1 - 0.023 13.1 0.0 0.085 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_30 PF13604.1 OAJ31909.1 - 0.059 12.9 0.2 0.14 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 OAJ31909.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase PX PF00787.19 OAJ31910.1 - 1e-11 44.5 0.0 2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 PX domain SpoIIIAH PF12685.2 OAJ31910.1 - 1.1 8.7 3.3 2.4 7.5 2.3 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein 4HBT PF03061.17 OAJ31911.1 - 1.3e-06 28.4 0.0 2.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DUF1180 PF06679.7 OAJ31911.1 - 2.9 7.7 5.6 0.75 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) A_deaminase PF00962.17 OAJ31912.1 - 2.5e-108 361.9 0.1 3.4e-108 361.4 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase TPT PF03151.11 OAJ31913.1 - 8.3e-32 109.9 7.5 8.3e-32 109.9 5.2 2.4 3 1 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 OAJ31913.1 - 6.2e-11 42.4 20.9 3.6e-06 27.0 4.5 2.7 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 OAJ31913.1 - 3.6e-08 32.7 15.0 9.5e-08 31.3 10.4 1.7 1 1 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.14 OAJ31913.1 - 0.021 15.3 5.0 0.021 15.3 3.4 2.2 2 0 0 2 2 2 0 Small Multidrug Resistance protein FXR1P_C PF12235.3 OAJ31913.1 - 4 7.5 8.3 6.1 6.9 5.8 1.2 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal WD40 PF00400.27 OAJ31914.1 - 2.1e-62 204.9 24.1 2.7e-11 42.8 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 OAJ31914.1 - 5.4e-05 21.5 7.5 0.058 11.5 0.2 3.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 OAJ31914.1 - 0.0016 18.1 0.0 0.0072 16.0 0.0 2.0 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 OAJ31914.1 - 0.07 11.4 0.0 3.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.7 OAJ31914.1 - 0.52 10.0 3.4 41 3.9 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Isy1 PF06246.7 OAJ31916.1 - 1.2e-71 241.1 3.6 5.4e-71 238.9 2.5 1.8 1 1 0 1 1 1 1 Isy1-like splicing family ADPrib_exo_Tox PF03496.9 OAJ31916.1 - 0.13 11.4 0.6 0.84 8.8 0.4 2.0 1 1 0 1 1 1 0 ADP-ribosyltransferase exoenzyme MOZ_SAS PF01853.13 OAJ31918.1 - 3.9e-56 189.2 0.2 6.7e-56 188.5 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family FRQ PF09421.5 OAJ31918.1 - 0.097 10.4 0.4 0.14 9.9 0.3 1.1 1 0 0 1 1 1 0 Frequency clock protein Ribosomal_L30 PF00327.15 OAJ31919.1 - 2.5e-09 36.5 0.2 3.4e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_60s PF00428.14 OAJ31919.1 - 0.06 13.7 0.8 0.06 13.7 0.6 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein SAC3_GANP PF03399.11 OAJ31921.1 - 5.4e-27 94.6 0.0 8.6e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 OAJ31921.1 - 7.7e-25 87.3 0.0 1.6e-24 86.2 0.0 1.6 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 NAM PF02365.10 OAJ31921.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 No apical meristem (NAM) protein Mak10 PF04112.8 OAJ31923.1 - 6.1e-39 132.9 0.0 1.1e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase AAA_11 PF13086.1 OAJ31924.1 - 2.1e-51 174.8 5.1 9.6e-51 172.6 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_12 PF13087.1 OAJ31924.1 - 2.5e-49 167.3 0.0 7.4e-49 165.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ31924.1 - 2.3e-13 49.7 2.9 3.8e-12 45.7 0.0 3.3 3 0 0 3 3 3 1 Part of AAA domain Viral_helicase1 PF01443.13 OAJ31924.1 - 0.00022 20.8 0.0 0.4 10.1 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 OAJ31924.1 - 0.0014 17.9 0.3 1.2 8.3 0.0 2.7 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 OAJ31924.1 - 0.0015 18.0 0.0 0.52 9.7 0.0 2.5 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 OAJ31924.1 - 0.0016 18.5 0.0 0.0071 16.4 0.0 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.24 OAJ31924.1 - 0.0029 17.7 0.1 0.025 14.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 OAJ31924.1 - 0.003 16.9 0.0 0.026 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ31924.1 - 0.0035 17.3 1.2 0.016 15.1 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 OAJ31924.1 - 0.0086 16.2 0.0 0.063 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain PIF1 PF05970.9 OAJ31924.1 - 0.086 11.7 0.0 0.3 10.0 0.0 1.7 2 0 0 2 2 2 0 PIF1-like helicase AAA_23 PF13476.1 OAJ31924.1 - 0.31 11.3 8.1 0.48 10.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain MGC-24 PF05283.6 OAJ31925.1 - 3.2 7.5 18.6 0.86 9.3 10.7 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Synaptobrevin PF00957.16 OAJ31926.1 - 6e-33 112.3 1.8 6.9e-33 112.1 1.2 1.0 1 0 0 1 1 1 1 Synaptobrevin GP41 PF00517.12 OAJ31926.1 - 0.02 14.4 0.2 0.031 13.8 0.1 1.2 1 0 0 1 1 1 0 Retroviral envelope protein DUF2976 PF11190.3 OAJ31926.1 - 0.08 12.4 0.6 0.14 11.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Chitin_synth_1 PF01644.12 OAJ31927.1 - 3.7e-87 290.2 0.1 6.4e-87 289.4 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 OAJ31927.1 - 2.1e-31 107.4 0.2 4.8e-31 106.2 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Ion_trans_2 PF07885.11 OAJ31927.1 - 2.5e-29 100.7 35.2 6.1e-16 57.9 7.4 3.4 3 0 0 3 3 3 2 Ion channel Chitin_synth_2 PF03142.10 OAJ31927.1 - 2.2e-21 75.8 3.2 9.5e-20 70.4 0.0 2.2 1 1 1 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 OAJ31927.1 - 2.8e-08 33.7 0.2 9.9e-08 31.9 0.2 2.0 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ31927.1 - 0.025 14.3 0.0 0.066 13.0 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Lig_chan PF00060.21 OAJ31927.1 - 0.98 9.1 6.9 6.5 6.4 1.3 2.9 2 1 0 2 2 2 0 Ligand-gated ion channel NUDIX PF00293.23 OAJ31928.1 - 5.8e-28 97.2 0.0 8.9e-28 96.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain FAM101 PF15068.1 OAJ31929.1 - 0.014 14.8 1.4 0.014 14.8 0.9 2.0 1 1 0 2 2 2 0 FAM101 family YscJ_FliF_C PF08345.6 OAJ31929.1 - 1 9.3 6.9 0.69 9.8 2.1 2.4 2 0 0 2 2 2 0 Flagellar M-ring protein C-terminal Cpn10 PF00166.16 OAJ31930.1 - 3.1e-25 87.9 0.0 3.5e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DEAD PF00270.24 OAJ31931.1 - 1.4e-42 145.0 0.1 2.3e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ31931.1 - 1.8e-20 72.5 0.0 3.4e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 OAJ31931.1 - 4e-20 71.1 0.2 9.1e-20 69.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) RRM_5 PF13893.1 OAJ31932.1 - 1.9e-09 37.2 0.0 2.8e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ31932.1 - 2.3e-09 36.7 0.0 8.3e-09 34.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ31932.1 - 0.00065 19.6 0.0 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-AN1 PF01428.11 OAJ31933.1 - 4.1e-18 64.9 28.0 1e-09 38.1 6.6 2.4 2 0 0 2 2 2 2 AN1-like Zinc finger Cpn60_TCP1 PF00118.19 OAJ31934.1 - 1.3e-119 399.9 6.4 1.7e-119 399.6 4.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RVT_2 PF07727.9 OAJ31936.1 - 1.2e-86 289.7 0.0 1.6e-86 289.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ31936.1 - 7.8e-22 77.6 0.1 2.2e-21 76.1 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ31936.1 - 3e-05 23.5 0.1 9e-05 22.0 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ31936.1 - 0.00033 20.1 0.6 0.0049 16.3 0.4 2.7 1 1 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ31936.1 - 0.042 13.2 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1090 PF06476.7 OAJ31938.1 - 0.005 16.4 1.8 0.012 15.2 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1090) PapD-like PF14874.1 OAJ31938.1 - 0.014 15.3 0.0 26 4.8 0.0 3.6 4 0 0 4 4 4 0 Flagellar-associated PapD-like Vps51 PF08700.6 OAJ31939.1 - 4.5e-16 58.4 0.4 1.3e-15 56.9 0.3 1.8 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 OAJ31939.1 - 1.5e-06 28.1 0.5 3.8e-06 26.7 0.3 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 CRAL_TRIO PF00650.15 OAJ31940.1 - 7e-30 103.6 0.0 9.3e-30 103.2 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 OAJ31940.1 - 1.9e-09 37.6 0.0 2.6e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain UBN2 PF14223.1 OAJ31941.1 - 3.8e-07 29.8 0.0 7.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ31941.1 - 2.9e-05 23.7 1.8 2.9e-05 23.7 1.2 1.8 2 0 0 2 2 2 1 Zinc knuckle SSF PF00474.12 OAJ31943.1 - 8.4e-21 74.0 27.3 1.5e-20 73.1 19.0 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DHH PF01368.15 OAJ31944.1 - 0.00011 21.9 0.0 0.00079 19.0 0.0 2.1 1 1 0 1 1 1 1 DHH family DUF726 PF05277.7 OAJ31946.1 - 4.6e-32 111.2 15.4 5.8e-23 81.3 8.1 3.8 2 2 0 2 2 2 2 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 OAJ31946.1 - 8.9e-05 22.4 1.0 0.00022 21.2 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 OAJ31946.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_5 PF12695.2 OAJ31946.1 - 0.0056 16.4 0.1 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 OAJ31946.1 - 0.014 14.6 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 OAJ31946.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF46 PF01864.12 OAJ31946.1 - 6.3 6.6 9.1 13 5.6 3.2 2.4 2 0 0 2 2 2 0 Putative integral membrane protein DUF46 Abhydrolase_6 PF12697.2 OAJ31947.1 - 5e-12 46.1 0.6 5e-12 46.1 0.4 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ31947.1 - 0.0092 15.5 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold CoA_transf_3 PF02515.12 OAJ31948.1 - 4.8e-67 224.9 0.1 7.9e-67 224.2 0.1 1.4 1 0 0 1 1 1 1 CoA-transferase family III Galactosyl_T PF01762.16 OAJ31949.1 - 1.6e-12 47.4 0.4 2.6e-07 30.4 0.0 3.2 1 1 1 3 3 3 3 Galactosyltransferase DUF2628 PF10947.3 OAJ31949.1 - 0.051 13.3 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) YTH PF04146.10 OAJ31950.1 - 1.8e-42 144.2 0.0 1.3e-41 141.5 0.0 2.2 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 OAJ31950.1 - 0.0033 17.0 0.0 0.63 9.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ31950.1 - 0.14 11.9 0.0 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glutaredoxin PF00462.19 OAJ31951.1 - 9.4e-19 67.1 0.0 5.1e-18 64.8 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 OAJ31951.1 - 5.6e-16 58.1 0.0 9.5e-16 57.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 OAJ31951.1 - 1.6e-05 24.8 0.1 0.02 14.9 0.0 3.0 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ31951.1 - 0.0046 17.1 0.0 0.028 14.6 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.6 OAJ31951.1 - 0.0079 16.0 0.0 0.03 14.2 0.0 1.9 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE GST_N_3 PF13417.1 OAJ31951.1 - 0.02 15.0 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Nucleoplasmin PF03066.10 OAJ31951.1 - 0.027 13.9 0.7 0.034 13.6 0.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin ArsC PF03960.10 OAJ31951.1 - 0.081 13.0 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 ArsC family Sigma70_ner PF04546.8 OAJ31951.1 - 0.084 12.4 1.5 0.13 11.8 1.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 OAJ31951.1 - 0.24 10.5 3.5 0.33 10.0 2.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region EF-hand_1 PF00036.27 OAJ31952.1 - 5.8e-25 84.6 7.4 3.2e-08 32.3 0.0 4.9 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 OAJ31952.1 - 6.3e-23 80.6 8.7 1.2e-11 44.6 1.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 OAJ31952.1 - 3.3e-21 73.2 1.3 3.3e-06 26.5 0.1 4.6 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 OAJ31952.1 - 9.7e-13 47.5 6.6 0.00035 20.1 0.2 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 OAJ31952.1 - 7.5e-11 40.8 13.7 4.8e-05 22.5 0.0 4.5 5 1 0 5 5 5 3 EF hand EF-hand_4 PF12763.2 OAJ31952.1 - 6.4e-10 38.7 6.0 0.00081 19.0 0.1 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 OAJ31952.1 - 5.7e-06 26.1 0.6 0.00086 19.1 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain Mad3_BUB1_II PF08171.6 OAJ31952.1 - 0.0074 16.1 0.0 0.019 14.8 0.0 1.7 1 1 0 1 1 1 1 Mad3/BUB1 homology region 2 SPARC_Ca_bdg PF10591.4 OAJ31952.1 - 0.033 14.2 1.9 1.5 8.9 0.1 3.0 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.6 OAJ31952.1 - 0.054 13.5 0.0 1.6 8.8 0.0 2.5 2 1 0 2 2 2 0 EF hand S10_plectin PF03501.10 OAJ31952.1 - 0.059 13.2 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Plectin/S10 domain Use1 PF09753.4 OAJ31953.1 - 8.7e-05 22.0 0.0 0.0002 20.9 0.0 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 E1_DerP2_DerF2 PF02221.10 OAJ31954.1 - 1e-25 90.5 0.0 1.2e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 OAJ31954.1 - 0.0048 16.9 0.0 0.0062 16.5 0.0 1.1 1 0 0 1 1 1 1 ML-like domain Oligomerisation PF02410.10 OAJ31955.1 - 0.053 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Oligomerisation domain Dynamin_M PF01031.15 OAJ31956.1 - 1.5e-13 50.2 0.1 2e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region HsbA PF12296.3 OAJ31957.1 - 9.7e-12 44.8 4.7 1.5e-11 44.2 3.3 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A CheZ PF04344.8 OAJ31957.1 - 0.013 15.2 0.2 0.016 14.8 0.1 1.3 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Ribosomal_L22 PF00237.14 OAJ31957.1 - 0.1 12.5 2.8 2 8.3 0.2 2.6 2 1 0 2 2 2 0 Ribosomal protein L22p/L17e Dynamin_M PF01031.15 OAJ31958.1 - 0.00037 19.3 0.0 0.00045 19.0 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region Dynamin_M PF01031.15 OAJ31959.1 - 1.9e-24 86.0 0.0 2.6e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 OAJ31959.1 - 9.8e-22 77.5 0.0 1.3e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Dynamin family zf-H2C2_2 PF13465.1 OAJ31961.1 - 1.1e-09 38.1 17.7 7.8e-06 25.9 2.9 4.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ31961.1 - 2.6e-08 33.7 12.3 0.0007 19.7 1.2 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type 14-3-3 PF00244.15 OAJ31962.1 - 1.1e-118 394.5 5.3 1.2e-118 394.3 3.7 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 OAJ31962.1 - 0.009 15.5 3.7 1 8.8 0.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF837) HisKA PF00512.20 OAJ31962.1 - 0.16 11.9 2.2 2.5 8.1 0.1 2.8 2 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain RabGAP-TBC PF00566.13 OAJ31963.1 - 4.1e-48 163.6 0.0 6.4e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 OAJ31963.1 - 1.2e-07 31.1 0.0 3.8e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 GRAM domain NUDIX PF00293.23 OAJ31964.1 - 6.9e-09 35.4 0.0 2.3e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain LIM PF00412.17 OAJ31965.1 - 1.4e-19 69.9 18.4 3.1e-11 43.1 4.5 3.0 2 1 0 2 2 2 2 LIM domain Cytochrom_c3_2 PF14537.1 OAJ31965.1 - 2.1 8.7 12.8 2 8.7 3.7 2.4 2 0 0 2 2 2 0 Cytochrome c3 zf-FPG_IleRS PF06827.9 OAJ31965.1 - 3.6 7.3 0.0 3.6 7.3 0.0 4.9 6 0 0 6 6 6 0 Zinc finger found in FPG and IleRS RhoGAP PF00620.22 OAJ31966.1 - 3.7e-43 146.7 0.0 6.4e-43 145.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PX PF00787.19 OAJ31966.1 - 4.2e-05 23.3 0.0 8.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 PX domain PH PF00169.24 OAJ31966.1 - 0.0012 18.9 0.0 0.0091 16.1 0.0 2.2 1 1 0 1 1 1 1 PH domain Clat_adaptor_s PF01217.15 OAJ31967.1 - 6e-09 35.7 0.0 8e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain IL6 PF00489.12 OAJ31967.1 - 0.09 12.3 0.2 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family DUF4266 PF14086.1 OAJ31967.1 - 0.13 12.8 8.8 0.63 10.5 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4266) RRM_1 PF00076.17 OAJ31968.1 - 3.8e-71 234.6 0.0 2.1e-18 65.7 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ31968.1 - 1e-64 214.4 0.8 1.1e-16 60.5 0.0 6.1 5 1 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ31968.1 - 1e-37 127.7 0.0 1.6e-08 34.2 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 OAJ31968.1 - 0.00052 19.7 3.9 0.13 12.0 0.0 5.1 5 1 1 6 6 6 1 Limkain b1 RRM_2 PF04059.7 OAJ31968.1 - 0.022 14.7 0.0 6.3 6.8 0.0 3.5 3 0 0 3 3 3 0 RNA recognition motif 2 Nup35_RRM_2 PF14605.1 OAJ31968.1 - 0.14 11.9 0.0 7.2 6.4 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif NMO PF03060.10 OAJ31970.1 - 1e-47 162.9 1.3 2.2e-29 102.6 0.1 3.1 2 2 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 OAJ31970.1 - 0.052 12.3 0.1 0.052 12.3 0.0 2.0 3 0 0 3 3 3 0 FMN-dependent dehydrogenase ABC2_membrane PF01061.19 OAJ31971.1 - 8.2e-66 221.1 52.8 4.3e-34 117.5 13.7 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 OAJ31971.1 - 7.9e-37 126.6 0.0 1.1e-18 67.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 OAJ31971.1 - 8.7e-20 70.3 0.0 8.7e-20 70.3 0.0 3.4 3 0 0 3 3 3 1 CDR ABC transporter AAA_25 PF13481.1 OAJ31971.1 - 5.1e-09 35.8 0.2 2.8e-05 23.6 0.1 3.4 3 0 0 3 3 3 2 AAA domain ABC_trans_N PF14510.1 OAJ31971.1 - 4.2e-07 29.9 0.2 1.1e-06 28.5 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_29 PF13555.1 OAJ31971.1 - 1.4e-05 24.5 1.0 0.043 13.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 OAJ31971.1 - 0.00019 20.6 0.3 0.024 13.8 0.1 2.9 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 OAJ31971.1 - 0.0013 18.9 0.7 1.4 9.0 0.1 3.4 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.13 OAJ31971.1 - 0.0019 17.7 0.8 0.39 10.1 0.0 3.2 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_16 PF13191.1 OAJ31971.1 - 0.0049 16.8 4.6 0.27 11.1 1.3 3.1 2 1 0 2 2 2 1 AAA ATPase domain UPF0079 PF02367.12 OAJ31971.1 - 0.005 16.4 4.6 0.89 9.1 0.2 3.2 3 0 0 3 3 3 2 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 OAJ31971.1 - 0.0079 16.1 0.0 0.71 9.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ31971.1 - 0.0087 16.8 0.2 0.2 12.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain DUF150 PF02576.12 OAJ31971.1 - 0.016 14.8 0.0 5.4 6.5 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised BCR, YhbC family COG0779 MMR_HSR1 PF01926.18 OAJ31971.1 - 0.025 14.5 0.1 8.1 6.4 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 OAJ31971.1 - 0.027 14.0 2.0 1 8.9 0.1 3.2 3 0 0 3 3 3 0 AAA domain PhnG PF06754.7 OAJ31971.1 - 0.035 13.7 0.1 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG cobW PF02492.14 OAJ31971.1 - 0.096 12.1 3.3 0.11 11.9 0.7 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 OAJ31971.1 - 0.3 11.0 4.7 0.14 12.1 0.4 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 OAJ31971.1 - 2.9 8.2 4.7 2.3 8.5 0.7 2.7 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.1 OAJ31971.1 - 7.8 6.3 6.8 5.8 6.7 0.2 3.3 3 1 1 4 4 3 0 AAA domain eIF-5a PF01287.15 OAJ31972.1 - 6.7e-28 96.4 1.2 9.5e-28 95.9 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 OAJ31972.1 - 8.4e-05 22.1 0.6 0.0002 20.9 0.4 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 OAJ31972.1 - 0.043 13.7 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Pil1 PF13805.1 OAJ31972.1 - 0.052 12.6 0.0 0.069 12.2 0.0 1.1 1 0 0 1 1 1 0 Eisosome component PIL1 Adaptin_N PF01602.15 OAJ31973.1 - 6.9e-125 417.3 8.8 8.4e-125 417.0 6.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 OAJ31973.1 - 2.4e-40 137.0 0.0 7.7e-40 135.3 0.0 1.9 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 OAJ31973.1 - 5.3e-19 68.6 0.0 2.7e-18 66.3 0.0 2.1 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT PF02985.17 OAJ31973.1 - 8 6.8 6.9 8.2 6.8 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat Ribosomal_L5_C PF00673.16 OAJ31975.1 - 4.1e-05 23.2 0.0 0.00014 21.5 0.0 1.8 1 1 0 1 1 1 1 ribosomal L5P family C-terminus DUF543 PF04418.7 OAJ31975.1 - 0.059 13.3 0.5 0.16 11.9 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF543) SAGA-Tad1 PF12767.2 OAJ31976.1 - 2e-47 161.9 0.0 3.4e-47 161.2 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit DUF4637 PF15470.1 OAJ31976.1 - 1.7 8.2 7.9 0.08 12.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) BRF1 PF07741.8 OAJ31976.1 - 5.6 7.2 10.6 1.9 8.7 1.8 2.9 3 0 0 3 3 3 0 Brf1-like TBP-binding domain CHCH PF06747.8 OAJ31978.1 - 1.4e-06 28.0 5.6 2.1e-06 27.5 3.9 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 OAJ31978.1 - 0.026 14.5 3.4 0.22 11.5 2.6 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 OAJ31978.1 - 0.11 12.5 1.0 0.16 12.0 0.7 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 OAJ31978.1 - 0.25 11.1 4.9 0.6 9.9 3.4 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 OAJ31978.1 - 0.41 10.5 2.1 3.3 7.6 0.1 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) COX17 PF05051.8 OAJ31978.1 - 0.64 10.0 4.5 2.4 8.2 0.4 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) PhoD PF09423.5 OAJ31980.1 - 1.4e-43 149.1 0.1 4.5e-43 147.4 0.1 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase zf-HC5HC2H_2 PF13832.1 OAJ31982.1 - 1.3e-19 70.2 2.1 1.3e-19 70.2 1.4 4.6 4 1 0 4 4 4 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 OAJ31982.1 - 1.6e-16 60.1 2.0 1.6e-16 60.1 1.4 4.9 5 0 0 5 5 5 2 PHD-like zinc-binding domain PHD PF00628.24 OAJ31982.1 - 6.7e-15 54.5 47.1 2.6e-09 36.6 4.1 5.3 6 0 0 6 6 6 3 PHD-finger BAH PF01426.13 OAJ31982.1 - 1.1e-08 34.8 0.0 2.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 BAH domain GATA PF00320.22 OAJ31982.1 - 6.7e-07 28.5 4.1 6.7e-07 28.5 2.9 4.3 5 0 0 5 5 5 1 GATA zinc finger PHD_2 PF13831.1 OAJ31982.1 - 5e-05 22.5 2.8 5e-05 22.5 1.9 5.8 6 0 0 6 6 6 2 PHD-finger ELM2 PF01448.19 OAJ31982.1 - 0.11 13.1 0.0 0.32 11.6 0.0 1.8 1 0 0 1 1 1 0 ELM2 domain DUF498 PF04430.9 OAJ31983.1 - 3.9e-25 87.5 0.0 6.1e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Cyclin PF08613.6 OAJ31984.1 - 2.8e-13 50.5 0.0 5.5e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 OAJ31984.1 - 4.2e-05 23.1 0.0 7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF466 PF04328.8 OAJ31984.1 - 0.055 13.2 4.0 0.16 11.8 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF466) CBF PF03914.12 OAJ31984.1 - 0.058 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 CBF/Mak21 family WD40 PF00400.27 OAJ31985.1 - 5.4e-07 29.2 7.2 1.5e-05 24.6 0.2 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF2415 PF10313.4 OAJ31985.1 - 0.035 13.7 0.0 14 5.4 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) tRNA-synt_2b PF00587.20 OAJ31987.1 - 4.9e-33 114.1 0.0 9.1e-33 113.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 OAJ31987.1 - 8.9e-18 64.2 3.0 8.9e-18 64.2 2.1 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain FlxA PF14282.1 OAJ31987.1 - 0.08 12.8 2.8 0.058 13.3 0.8 1.6 2 0 0 2 2 2 0 FlxA-like protein IFT57 PF10498.4 OAJ31987.1 - 0.098 11.3 5.3 2.6 6.7 0.7 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Serglycin PF04360.7 OAJ31988.1 - 0.0033 17.1 2.4 0.0095 15.6 0.9 2.1 2 0 0 2 2 2 1 Serglycin zf-C2H2_4 PF13894.1 OAJ31988.1 - 0.13 12.6 10.1 2 8.9 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 OAJ31988.1 - 0.16 12.3 0.2 0.16 12.3 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF3246 PF11596.3 OAJ31988.1 - 6 6.0 9.1 13 5.0 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) RVT_1 PF00078.22 OAJ31991.1 - 3.6e-08 33.0 0.1 6.2e-06 25.7 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ31991.1 - 0.00011 22.5 0.1 0.0003 21.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ31991.1 - 0.0017 18.2 0.0 0.0046 16.8 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ31991.1 - 0.0058 16.4 0.6 0.018 14.8 0.2 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease SSP160 PF06933.6 OAJ31993.1 - 1.6 6.6 14.4 1.9 6.3 10.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PsbW PF07123.7 OAJ31993.1 - 7.4 6.6 7.1 1.6 8.7 2.3 1.7 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) TFIIA PF03153.8 OAJ31993.1 - 9.9 5.9 6.6 11 5.7 4.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Abhydrolase_4 PF08386.5 OAJ31995.1 - 3.4e-14 52.5 0.0 1.5e-13 50.4 0.0 2.0 1 1 1 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 OAJ31995.1 - 4.2e-12 46.1 0.0 8.8e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ31995.1 - 7.5e-08 32.5 0.0 6.3e-07 29.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ31995.1 - 4.6e-05 23.2 0.0 0.00021 21.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cep57_MT_bd PF06657.8 OAJ31996.1 - 7.1e-10 38.7 2.0 7.1e-10 38.7 1.4 3.1 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 Vpu PF00558.14 OAJ31996.1 - 0.19 11.2 3.9 15 5.2 2.1 2.8 2 0 0 2 2 2 0 Vpu protein Pkinase PF00069.20 OAJ31997.1 - 1.6e-66 224.1 0.0 2.3e-66 223.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ31997.1 - 1.8e-42 145.2 0.0 2.8e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 OAJ31997.1 - 2.9e-13 49.6 0.0 7.5e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 OAJ31997.1 - 3.4e-12 46.3 0.1 9e-12 45.0 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 OAJ31997.1 - 3.6e-12 45.9 0.0 6.4e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 OAJ31997.1 - 1.6e-07 30.6 0.0 0.00062 18.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 OAJ31997.1 - 0.052 12.6 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RA PF00788.18 OAJ31997.1 - 0.083 13.3 0.0 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Nop14 PF04147.7 OAJ31997.1 - 0.31 8.9 6.2 0.47 8.3 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family Seadorna_VP7 PF07387.6 OAJ31997.1 - 1.3 7.8 0.0 2.7 6.7 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 NOA36 PF06524.7 OAJ31997.1 - 4.1 6.5 4.8 7 5.8 3.3 1.3 1 0 0 1 1 1 0 NOA36 protein CK1gamma_C PF12605.3 OAJ31998.1 - 0.91 10.1 5.3 0.45 11.1 0.1 2.7 3 0 0 3 3 3 0 Casein kinase 1 gamma C terminal COesterase PF00135.23 OAJ31999.1 - 3.4e-58 197.6 0.0 2.2e-57 194.9 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ31999.1 - 3.1e-12 46.5 0.2 1.4e-11 44.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ31999.1 - 0.0032 17.2 0.1 0.0071 16.1 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAJ31999.1 - 0.013 14.9 0.6 0.027 13.8 0.4 1.4 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 OAJ31999.1 - 0.026 13.7 0.1 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.4 OAJ31999.1 - 0.044 13.0 0.1 0.094 11.9 0.1 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase DcpS_C PF11969.3 OAJ32000.1 - 2.8e-09 37.2 0.3 9.6e-09 35.4 0.2 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 OAJ32000.1 - 7.5e-06 26.4 0.7 0.099 13.1 0.1 2.4 2 0 0 2 2 2 2 HIT domain Dimer_Tnp_hAT PF05699.9 OAJ32001.1 - 1.4e-23 82.3 0.0 3.1e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAJ32001.1 - 0.005 16.7 0.0 0.21 11.5 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4413) PP_kinase_C PF13090.1 OAJ32001.1 - 0.12 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain RhoGEF PF00621.15 OAJ32002.1 - 2.8e-31 108.7 0.0 4.4e-26 91.8 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain DUF4547 PF15080.1 OAJ32002.1 - 1.8 7.9 0.0 3.1 7.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4547) 3-HAO PF06052.7 OAJ32003.1 - 7.9e-59 197.3 0.0 9.1e-59 197.2 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 OAJ32003.1 - 3.1e-07 29.7 0.1 4.5e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 OAJ32003.1 - 0.00033 20.1 0.0 0.00048 19.5 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 OAJ32003.1 - 0.035 13.7 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain ARD PF03079.9 OAJ32003.1 - 0.064 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family RVT_1 PF00078.22 OAJ32004.1 - 4.1e-32 111.2 0.0 6.4e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAJ32004.1 - 3.7e-12 46.7 0.0 7.9e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 RNase H Ribosomal_S10 PF00338.17 OAJ32005.1 - 1.2e-19 69.8 0.0 2.1e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DEAD PF00270.24 OAJ32006.1 - 2.4e-13 49.9 0.0 4.6e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ32006.1 - 0.00055 19.7 0.0 0.0019 18.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCHC_4 PF14392.1 OAJ32007.1 - 5.7 6.6 10.6 4 7.1 1.5 3.1 2 1 1 3 3 3 0 Zinc knuckle Med3 PF11593.3 OAJ32007.1 - 9.7 5.3 19.9 20 4.2 13.8 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glycos_transf_1 PF00534.15 OAJ32008.1 - 4e-18 65.4 0.0 1.6e-12 47.1 0.0 3.1 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 OAJ32008.1 - 8.3e-06 25.6 0.1 0.00048 19.8 0.0 3.0 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 OAJ32008.1 - 0.0043 17.2 0.1 0.03 14.4 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 OAJ32008.1 - 0.01 16.0 2.7 0.01 16.0 1.8 2.8 3 1 0 3 3 3 0 Glycosyl transferase 4-like domain ADH_zinc_N PF00107.21 OAJ32009.1 - 8e-20 70.7 0.0 1.4e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ32009.1 - 1.1e-06 29.5 0.0 2.5e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 OAJ32009.1 - 0.011 15.3 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Epimerase PF01370.16 OAJ32009.1 - 0.021 14.2 0.0 0.048 13.0 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ32009.1 - 0.056 13.4 1.2 0.11 12.4 0.9 1.5 1 0 0 1 1 1 0 NADH(P)-binding RRM_1 PF00076.17 OAJ32010.1 - 9.9e-09 34.7 0.0 1.6e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ32010.1 - 7.3e-08 32.2 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ32010.1 - 0.00028 20.6 0.0 0.0005 19.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bin3 PF06859.7 OAJ32011.1 - 1.2e-14 54.2 0.0 2e-08 34.1 0.0 3.1 3 0 0 3 3 3 2 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 OAJ32011.1 - 2e-05 25.1 0.0 5.3e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ32011.1 - 0.00055 19.9 0.0 0.027 14.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ32011.1 - 0.0012 18.4 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ32011.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ32011.1 - 0.026 15.0 0.0 0.07 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF3446 PF11928.3 OAJ32011.1 - 0.15 12.2 7.7 0.066 13.4 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) PI-PLC-X PF00388.14 OAJ32012.1 - 2.1e-45 153.7 0.0 3.4e-45 153.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 OAJ32012.1 - 4.5e-32 110.4 0.0 9.1e-32 109.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 OAJ32012.1 - 0.96 9.3 3.3 4 7.3 0.9 2.7 2 1 0 2 2 2 0 C2 domain F-box-like PF12937.2 OAJ32013.1 - 3.7e-06 26.5 0.1 7.8e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like BSP_II PF05432.6 OAJ32013.1 - 0.0015 17.8 0.3 0.0015 17.8 0.2 3.2 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) F-box PF00646.28 OAJ32013.1 - 0.017 14.7 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 F-box domain Nucleo_P87 PF07267.6 OAJ32013.1 - 0.33 9.6 0.3 0.52 8.9 0.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NAD_binding_8 PF13450.1 OAJ32014.1 - 1.9e-12 46.9 0.1 4.3e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ32014.1 - 8.5e-12 44.6 1.1 9.7e-11 41.1 0.7 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 OAJ32014.1 - 7.8e-07 28.5 0.2 2.2e-05 23.7 0.1 2.7 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 OAJ32014.1 - 1.3e-05 25.2 0.0 3.1e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAJ32014.1 - 3.4e-05 22.8 1.0 8.3e-05 21.6 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 OAJ32014.1 - 0.00016 21.9 3.7 0.00067 20.0 0.8 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ32014.1 - 0.0021 16.6 0.2 0.003 16.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 OAJ32014.1 - 0.0034 16.4 1.0 0.0068 15.5 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 OAJ32014.1 - 0.0052 16.3 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 OAJ32014.1 - 0.0087 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 OAJ32014.1 - 0.01 14.4 0.9 1.2 7.6 0.3 2.2 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.13 OAJ32014.1 - 0.016 15.1 0.1 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 OAJ32014.1 - 0.023 13.8 0.2 0.044 12.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 OAJ32014.1 - 0.028 13.8 0.4 0.056 12.8 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 OAJ32014.1 - 0.044 12.6 0.1 0.081 11.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Rossmann-like PF10727.4 OAJ32014.1 - 0.074 12.7 0.2 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 OAJ32014.1 - 0.086 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 OAJ32014.1 - 0.1 11.6 0.1 0.2 10.7 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 OAJ32014.1 - 0.11 12.1 0.3 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 OAJ32014.1 - 0.17 11.6 0.7 0.35 10.6 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 OAJ32014.1 - 0.17 12.1 0.2 0.98 9.7 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 OAJ32014.1 - 0.22 10.3 3.5 0.2 10.4 0.5 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A DnaJ PF00226.26 OAJ32015.1 - 6.1e-12 45.0 0.0 6.1e-12 45.0 0.0 2.1 2 1 0 2 2 1 1 DnaJ domain Peptidase_C37 PF05416.7 OAJ32015.1 - 0.00048 18.5 8.0 0.00058 18.2 5.5 1.1 1 0 0 1 1 1 1 Southampton virus-type processing peptidase SprA-related PF12118.3 OAJ32015.1 - 0.008 15.5 21.0 0.011 15.1 14.6 1.3 1 0 0 1 1 1 1 SprA-related family DUF1510 PF07423.6 OAJ32015.1 - 0.036 13.4 13.7 0.056 12.8 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SAGA-Tad1 PF12767.2 OAJ32015.1 - 0.056 13.1 13.3 0.066 12.8 9.2 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit RNase_H2-Ydr279 PF09468.5 OAJ32015.1 - 0.062 12.4 3.9 0.075 12.2 2.7 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) TFIIA PF03153.8 OAJ32015.1 - 0.14 11.9 20.8 0.17 11.7 14.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gag_spuma PF03276.9 OAJ32015.1 - 0.19 10.0 24.3 0.27 9.5 16.9 1.2 1 0 0 1 1 1 0 Spumavirus gag protein RR_TM4-6 PF06459.7 OAJ32015.1 - 0.42 10.4 15.7 0.56 10.0 10.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 OAJ32015.1 - 0.44 8.1 14.0 0.49 8.0 9.7 1.1 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 OAJ32015.1 - 0.53 10.0 11.1 0.71 9.6 7.7 1.3 1 0 0 1 1 1 0 DDHD domain DHHW PF14286.1 OAJ32015.1 - 0.78 8.9 7.5 0.92 8.7 5.2 1.1 1 0 0 1 1 1 0 DHHW protein FAM60A PF15396.1 OAJ32015.1 - 0.94 9.1 13.5 1.3 8.7 9.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Asp-B-Hydro_N PF05279.6 OAJ32015.1 - 1.1 9.0 15.5 1.4 8.7 10.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Herpes_DNAp_acc PF04929.7 OAJ32015.1 - 1.2 8.0 8.7 1.2 8.0 6.0 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PAT1 PF09770.4 OAJ32015.1 - 1.4 7.0 30.7 1.6 6.8 21.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.17 OAJ32015.1 - 1.8 7.5 4.4 2.3 7.1 3.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3260 PF11658.3 OAJ32015.1 - 2.2 6.3 7.5 3.3 5.7 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) RNA_pol_Rpb1_5 PF04998.12 OAJ32015.1 - 2.2 7.4 7.2 3.2 6.9 5.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF913 PF06025.7 OAJ32015.1 - 3 6.4 7.0 4.2 6.0 4.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.11 OAJ32015.1 - 3.4 7.4 11.0 4.4 7.1 7.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med15 PF09606.5 OAJ32015.1 - 3.9 5.5 34.0 4.6 5.3 23.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.12 OAJ32015.1 - 6.2 5.5 7.2 7.3 5.2 5.0 1.3 1 0 0 1 1 1 0 Presenilin DUF3492 PF11997.3 OAJ32015.1 - 7.7 5.9 9.1 11 5.4 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) DDRGK PF09756.4 OAJ32015.1 - 8.1 5.8 32.4 14 5.0 22.5 1.4 1 0 0 1 1 1 0 DDRGK domain CAF-1_p150 PF11600.3 OAJ32015.1 - 8.3 5.7 38.5 14 4.9 26.7 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Spore_coat_CotO PF14153.1 OAJ32015.1 - 8.8 5.7 24.6 12 5.2 17.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Gly-rich_Ago1 PF12764.2 OAJ32016.1 - 0.092 13.3 0.3 0.13 12.9 0.2 1.2 1 0 0 1 1 1 0 Glycine-rich region of argonaut Rad60-SLD PF11976.3 OAJ32017.1 - 4.2e-12 45.5 0.4 4.2e-12 45.5 0.3 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 OAJ32017.1 - 0.00056 19.2 0.1 0.0011 18.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DnaJ PF00226.26 OAJ32018.1 - 1.8e-08 34.0 0.1 2.3e-07 30.4 0.1 2.7 1 1 0 1 1 1 1 DnaJ domain MIP-T3 PF10243.4 OAJ32018.1 - 0.12 10.8 47.0 0.17 10.3 32.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF4028 PF13220.1 OAJ32019.1 - 0.021 14.4 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) COesterase PF00135.23 OAJ32020.1 - 1.3e-91 307.9 0.0 1.8e-91 307.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ32020.1 - 5e-06 26.2 0.3 0.0079 15.7 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2317 PF10079.4 OAJ32022.1 - 0.0022 16.6 1.0 0.0031 16.1 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2317) Sec62 PF03839.11 OAJ32022.1 - 0.0025 17.2 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 GAGA_bind PF06217.7 OAJ32022.1 - 0.095 12.6 3.6 0.12 12.3 2.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family TATR PF03430.8 OAJ32022.1 - 0.21 10.1 1.8 0.25 9.9 1.3 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF4337 PF14235.1 OAJ32022.1 - 0.29 10.9 3.5 0.59 9.9 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RR_TM4-6 PF06459.7 OAJ32022.1 - 0.94 9.3 6.9 1.2 9.0 4.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CAF-1_p150 PF11600.3 OAJ32022.1 - 2.2 7.6 25.8 3.2 7.0 17.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Phage_min_cap2 PF06152.6 OAJ32022.1 - 3.6 6.4 10.5 4.7 6.0 7.3 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 NARP1 PF12569.3 OAJ32022.1 - 4 6.0 10.4 5 5.7 7.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S8 PF00082.17 OAJ32023.1 - 1.9e-25 89.5 2.9 1.9e-25 89.5 2.0 1.9 2 0 0 2 2 2 1 Subtilase family DUF1034 PF06280.7 OAJ32023.1 - 9.9e-07 29.1 0.1 2.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 OAJ32023.1 - 1.8e-06 27.5 0.1 6.2e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 PA domain MFS_1 PF07690.11 OAJ32024.1 - 1.8e-26 92.7 63.6 3.7e-21 75.2 22.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ32024.1 - 2.3e-05 23.1 38.4 0.00065 18.3 8.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Sulfatase PF00884.18 OAJ32026.1 - 1.4e-58 198.5 0.0 2e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 OAJ32026.1 - 0.0015 18.7 0.1 0.17 12.1 0.0 2.7 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 OAJ32026.1 - 0.0039 16.5 0.0 0.0081 15.5 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 OAJ32026.1 - 0.008 14.6 0.0 0.011 14.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 OAJ32026.1 - 0.11 11.8 0.0 11 5.3 0.0 2.1 2 0 0 2 2 2 0 Metalloenzyme superfamily Metallophos PF00149.23 OAJ32027.1 - 1.6e-05 24.3 0.0 3.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAJ32027.1 - 0.00012 21.8 0.0 0.0031 17.3 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain ABC_membrane_2 PF06472.10 OAJ32028.1 - 2.4e-98 328.7 5.4 3.3e-98 328.2 3.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 OAJ32028.1 - 1.4e-17 64.2 0.0 3e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 OAJ32028.1 - 0.0017 19.1 0.0 0.0049 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAJ32028.1 - 0.0028 16.7 0.0 0.0065 15.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 OAJ32028.1 - 0.0071 15.5 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 OAJ32028.1 - 0.013 15.5 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 OAJ32028.1 - 0.019 15.1 0.1 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 OAJ32028.1 - 0.019 14.7 0.1 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_21 PF13304.1 OAJ32028.1 - 0.033 14.1 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 OAJ32028.1 - 0.034 13.6 0.0 0.14 11.7 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 OAJ32028.1 - 0.046 14.0 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAJ32028.1 - 0.09 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 OAJ32028.1 - 0.095 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 OAJ32028.1 - 0.099 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ32028.1 - 0.12 12.1 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 OAJ32028.1 - 0.14 12.1 0.0 0.43 10.6 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF3584 PF12128.3 OAJ32028.1 - 0.25 8.6 0.0 0.4 7.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SNO PF01174.14 OAJ32029.1 - 6.9e-51 172.5 0.0 6.9e-40 136.6 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 OAJ32029.1 - 1.8e-07 30.9 0.1 2.6e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 OAJ32029.1 - 0.00042 19.7 0.1 0.00063 19.2 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.12 OAJ32029.1 - 0.0036 17.0 0.0 0.0049 16.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DEC-1_N PF04625.8 OAJ32029.1 - 0.074 11.7 9.3 0.11 11.1 6.5 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region adh_short PF00106.20 OAJ32030.1 - 2.9e-05 24.0 0.0 6.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Collagen PF01391.13 OAJ32031.1 - 0.028 13.9 1.3 0.046 13.2 0.9 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) MFS_1 PF07690.11 OAJ32032.1 - 4.5e-36 124.2 12.0 6.8e-36 123.6 8.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DDE_1 PF03184.14 OAJ32034.1 - 3.9e-06 26.1 0.0 8e-06 25.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease SPRY PF00622.23 OAJ32035.1 - 5.6e-05 23.2 0.0 0.0057 16.7 0.0 3.3 3 0 0 3 3 3 1 SPRY domain Svf1 PF08622.5 OAJ32036.1 - 3.6e-85 285.8 0.0 7.4e-85 284.7 0.0 1.5 1 1 0 1 1 1 1 Svf1-like Spc97_Spc98 PF04130.8 OAJ32037.1 - 1.3e-65 221.7 0.0 1.7e-65 221.3 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Activator_LAG-3 PF11498.3 OAJ32037.1 - 5.9 5.5 23.2 9.7 4.8 16.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4557 PF15101.1 OAJ32037.1 - 7.9 6.2 8.5 14 5.3 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) MFS_1 PF07690.11 OAJ32038.1 - 4.5e-06 25.6 25.6 8.7e-06 24.6 17.8 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 OAJ32038.1 - 0.00011 21.7 5.5 0.00011 21.7 3.8 2.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 ComJ PF11033.3 OAJ32038.1 - 0.03 13.9 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Competence protein J (ComJ) DOMON PF03351.12 OAJ32039.1 - 0.00019 21.3 0.2 0.0003 20.7 0.1 1.3 1 0 0 1 1 1 1 DOMON domain DUF4079 PF13301.1 OAJ32039.1 - 0.046 13.7 0.4 0.096 12.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) CUE PF02845.11 OAJ32041.1 - 1.2e-12 47.0 0.1 1.9e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 CUE domain LIP PF03583.9 OAJ32042.1 - 1.3e-48 165.7 0.0 1.8e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.16 OAJ32042.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family eIF3g PF12353.3 OAJ32043.1 - 1.3e-40 138.2 1.4 2.2e-40 137.5 1.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 OAJ32043.1 - 2.9e-18 65.2 0.0 4.7e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ32043.1 - 3.7e-15 55.6 0.0 6.6e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ32043.1 - 1.4e-08 34.4 0.0 2.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Toxin_ToxA PF11584.3 OAJ32043.1 - 0.017 14.9 0.0 4.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Proteinaceous host-selective toxin ToxA MerB PF03243.10 OAJ32043.1 - 0.12 12.2 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Alkylmercury lyase CTD_bind PF04818.8 OAJ32044.1 - 0.0003 20.9 0.0 0.022 14.9 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Mito_fiss_reg PF05308.6 OAJ32044.1 - 3.9 6.7 9.1 9.3 5.5 6.3 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator Ribosomal_L17 PF01196.14 OAJ32045.1 - 3.6e-25 88.3 0.5 1.4e-24 86.4 0.0 2.3 3 0 0 3 3 3 1 Ribosomal protein L17 Ribosomal_L11_N PF03946.9 OAJ32045.1 - 5e-24 83.5 0.7 1.1e-23 82.4 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 OAJ32045.1 - 6e-21 74.3 0.3 1.4e-20 73.1 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Clat_adaptor_s PF01217.15 OAJ32046.1 - 1.5e-19 70.1 0.0 2.4e-16 59.7 0.0 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain K_channel_TID PF07941.6 OAJ32046.1 - 0.69 10.1 2.9 8.7 6.6 0.3 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Nup84_Nup100 PF04121.8 OAJ32047.1 - 7.2e-80 268.5 0.0 2.9e-38 131.0 0.0 4.3 4 0 0 4 4 4 4 Nuclear pore protein 84 / 107 ThiF PF00899.16 OAJ32048.1 - 1.2e-09 38.0 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family ThiF PF00899.16 OAJ32049.1 - 7.4e-33 113.2 0.0 1.2e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 OAJ32049.1 - 0.0069 16.4 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TFIIB PF00382.14 OAJ32050.1 - 3.9e-39 132.3 3.1 2.7e-22 78.3 0.7 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 OAJ32050.1 - 1.6e-12 46.5 1.6 2.8e-12 45.7 1.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 OAJ32050.1 - 0.004 17.0 0.0 3.5 7.5 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain Cyclin_N PF00134.18 OAJ32050.1 - 0.07 12.7 0.7 0.24 10.9 0.1 1.9 2 0 0 2 2 2 0 Cyclin, N-terminal domain adh_short PF00106.20 OAJ32051.1 - 4.4e-18 65.7 0.5 9.6e-13 48.3 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 OAJ32051.1 - 2e-06 27.6 2.3 1.5e-05 24.7 1.5 2.4 1 1 0 1 1 1 1 KR domain ADH_N PF08240.7 OAJ32052.1 - 1.5e-20 72.9 2.7 2.7e-20 72.1 1.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ32052.1 - 5.2e-16 58.3 0.0 9.7e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 OAJ32052.1 - 1.8e-05 24.8 0.0 0.0018 18.4 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 OAJ32052.1 - 0.00011 21.4 0.1 0.0002 20.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.1 OAJ32052.1 - 0.0053 17.0 0.0 0.051 13.8 0.0 2.2 2 0 0 2 2 2 1 XdhC Rossmann domain 3HCDH_N PF02737.13 OAJ32052.1 - 0.0079 15.8 0.1 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 OAJ32052.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 OAJ32052.1 - 0.023 14.5 2.0 0.051 13.4 1.4 1.5 1 0 0 1 1 1 0 ThiF family GFO_IDH_MocA PF01408.17 OAJ32052.1 - 0.033 14.7 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PP-binding PF00550.20 OAJ32053.1 - 9.8e-16 57.7 0.4 1.6e-15 57.0 0.3 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 OAJ32053.1 - 3.8e-07 30.0 0.2 6.3e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 OAJ32053.1 - 0.076 13.1 0.1 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) FlaC_arch PF05377.6 OAJ32053.1 - 0.094 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Oxidored_FMN PF00724.15 OAJ32054.1 - 8e-60 202.6 0.0 1e-59 202.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 OAJ32054.1 - 0.039 12.8 0.0 0.099 11.4 0.0 1.6 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) DnaJ PF00226.26 OAJ32056.1 - 3.5e-16 58.6 0.1 7.2e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain MoCF_biosynth PF00994.19 OAJ32057.1 - 2.1e-52 176.3 0.3 5.5e-28 97.1 0.0 2.5 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 OAJ32057.1 - 4.1e-30 104.2 1.5 8.2e-30 103.2 1.0 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 OAJ32057.1 - 1e-14 54.2 0.1 2.8e-14 52.8 0.1 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) PyrBI_leader PF08052.6 OAJ32057.1 - 0.09 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 PyrBI operon leader peptide Metallophos PF00149.23 OAJ32058.1 - 2.9e-12 46.3 0.8 1.1e-11 44.5 0.5 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAJ32058.1 - 0.00014 21.7 0.0 0.00087 19.1 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Luteo_coat PF00894.13 OAJ32058.1 - 0.091 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Luteovirus coat protein Rav1p_C PF12234.3 OAJ32060.1 - 9e-88 295.0 0.0 1.2e-87 294.6 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal Pro_CA PF00484.14 OAJ32061.1 - 8.6e-29 100.5 0.1 1e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Syndecan PF01034.15 OAJ32062.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Hex_IIIa PF02455.11 OAJ32062.1 - 4.6 5.8 6.9 8.2 4.9 4.8 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) IPK PF03770.11 OAJ32063.1 - 3.2e-52 177.0 0.0 1.1e-51 175.3 0.0 1.9 2 0 0 2 2 2 1 Inositol polyphosphate kinase WD40 PF00400.27 OAJ32064.1 - 0.00058 19.6 0.3 0.0039 17.0 0.0 2.6 3 0 0 3 3 3 1 WD domain, G-beta repeat F-box PF00646.28 OAJ32065.1 - 0.0021 17.6 0.9 0.004 16.7 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 OAJ32065.1 - 0.0046 16.6 0.1 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 F-box-like domain Pkinase PF00069.20 OAJ32066.1 - 2.3e-58 197.3 0.0 1.4e-57 194.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ32066.1 - 1.1e-25 90.2 0.0 1.6e-24 86.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ32066.1 - 1.2e-08 34.2 0.0 2.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ32066.1 - 0.015 15.0 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ32066.1 - 0.037 12.8 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FAD_binding_2 PF00890.19 OAJ32068.1 - 1.5e-86 290.8 0.1 1.7e-86 290.6 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAJ32068.1 - 1.3e-08 34.7 0.3 7.7e-08 32.2 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAJ32068.1 - 1.5e-08 34.7 0.0 5.8e-05 23.0 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ32068.1 - 4.5e-07 29.1 0.1 2.8e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAJ32068.1 - 1.3e-06 27.7 0.1 4.9e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 OAJ32068.1 - 4.1e-06 27.1 1.8 8.5e-05 22.8 0.3 3.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ32068.1 - 9.4e-05 21.0 0.1 9.4e-05 21.0 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.2 OAJ32068.1 - 0.0011 18.1 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAJ32068.1 - 0.0012 17.8 0.6 0.0019 17.1 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 OAJ32068.1 - 0.0012 17.7 0.6 0.0012 17.7 0.4 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 OAJ32068.1 - 0.0016 18.1 0.3 0.0038 17.0 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 OAJ32068.1 - 0.0037 16.4 1.1 0.0079 15.3 0.1 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 OAJ32068.1 - 0.0045 17.0 0.4 0.01 15.9 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 OAJ32068.1 - 0.0081 16.4 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 OAJ32068.1 - 0.012 15.2 3.0 0.012 15.2 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 OAJ32068.1 - 0.15 11.4 0.1 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ribosomal_S5 PF00333.15 OAJ32069.1 - 5.3e-15 54.9 1.3 1.1e-14 53.8 0.9 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 OAJ32069.1 - 3.9e-14 51.6 0.0 9.5e-14 50.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain PRP1_N PF06424.7 OAJ32069.1 - 0.074 13.3 2.9 7.6 6.8 0.1 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal MRP PF09387.5 OAJ32069.1 - 0.081 12.6 1.3 0.13 11.9 0.9 1.3 1 0 0 1 1 1 0 Mitochondrial RNA binding protein MRP Pex14_N PF04695.8 OAJ32069.1 - 0.21 11.6 6.3 0.35 10.9 4.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Herpes_capsid PF06112.6 OAJ32069.1 - 2.4 8.2 20.2 6.1 6.8 14.0 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF566 PF04484.7 OAJ32069.1 - 3.3 7.1 14.4 5.3 6.4 10.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Period_C PF12114.3 OAJ32069.1 - 8.3 5.9 14.2 14 5.2 9.8 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region PilO PF04350.8 OAJ32070.1 - 8.7 6.2 9.3 1 9.2 1.2 2.4 1 1 1 2 2 2 0 Pilus assembly protein, PilO Rsa3 PF14615.1 OAJ32071.1 - 0.00078 18.6 0.0 0.0042 16.3 0.0 2.0 1 1 0 1 1 1 1 Ribosome-assembly protein 3 DUF3322 PF11795.3 OAJ32071.1 - 0.01 15.4 2.3 0.016 14.8 1.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) F-box PF00646.28 OAJ32072.1 - 4.4e-08 32.5 0.0 9.8e-08 31.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ32072.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 F-box-like Nucleoplasmin PF03066.10 OAJ32072.1 - 0.66 9.4 2.7 1 8.8 1.8 1.2 1 0 0 1 1 1 0 Nucleoplasmin Saccharop_dh PF03435.13 OAJ32073.1 - 2.5e-11 43.1 0.7 3.9e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase SRP14 PF02290.10 OAJ32075.1 - 2.2e-13 49.9 0.1 5.6e-12 45.4 0.0 2.8 2 1 0 2 2 2 1 Signal recognition particle 14kD protein DUF4200 PF13863.1 OAJ32075.1 - 0.57 10.1 9.6 3.8 7.4 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) HECT_2 PF09814.4 OAJ32078.1 - 1.5e-17 63.3 0.0 1.7e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Bromo_TP PF07524.8 OAJ32079.1 - 0.00085 18.9 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated tRNA-synt_2 PF00152.15 OAJ32080.1 - 7.1e-59 199.2 0.0 1.7e-56 191.4 0.0 3.1 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAJ32080.1 - 5.5e-05 22.9 0.0 0.00024 20.8 0.0 2.0 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Thiolase_N PF00108.18 OAJ32081.1 - 1.9e-67 227.0 0.0 9.6e-67 224.7 0.0 2.0 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAJ32081.1 - 1.4e-44 150.4 0.3 3.4e-44 149.1 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 OAJ32081.1 - 1.3e-05 24.8 0.2 3.3e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 OAJ32081.1 - 0.089 12.4 0.2 3.9 7.1 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III YTH PF04146.10 OAJ32082.1 - 1.8e-41 140.9 0.0 2.8e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain Mem_trans PF03547.13 OAJ32083.1 - 1.9e-41 141.6 1.1 1.3e-37 129.0 0.0 2.3 2 1 0 2 2 2 2 Membrane transport protein DUF2428 PF10350.4 OAJ32084.1 - 8.7e-45 152.7 1.3 2e-44 151.5 0.2 2.3 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 OAJ32084.1 - 0.0011 18.9 4.9 11 6.3 0.1 5.0 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 OAJ32084.1 - 0.0025 18.0 1.2 0.0025 18.0 0.8 3.9 4 0 0 4 4 4 1 HEAT repeats Nairo_nucleo PF02477.10 OAJ32084.1 - 0.16 10.6 0.1 0.6 8.7 0.0 1.8 2 0 0 2 2 2 0 Nucleocapsid N protein HEAT_EZ PF13513.1 OAJ32084.1 - 1.2 9.6 12.0 1.2 9.7 0.2 5.3 5 0 0 5 5 5 0 HEAT-like repeat dCMP_cyt_deam_1 PF00383.17 OAJ32085.1 - 2.4e-14 52.8 0.2 3.8e-14 52.1 0.1 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 OAJ32085.1 - 5.1e-12 45.8 1.6 1.8e-10 40.9 0.2 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 OAJ32085.1 - 0.00024 20.5 2.1 0.02 14.2 0.0 2.2 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Abhydrolase_2 PF02230.11 OAJ32086.1 - 1.1e-59 201.4 0.0 1.5e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 OAJ32086.1 - 2.1e-13 50.2 0.0 2.8e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ32086.1 - 3.8e-10 40.0 0.0 8.2e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ32086.1 - 0.0013 18.3 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 OAJ32086.1 - 0.011 15.0 0.0 0.026 13.7 0.0 1.8 1 1 1 2 2 2 0 Esterase PHB depolymerase Cutinase PF01083.17 OAJ32086.1 - 0.022 14.5 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase FSH1 PF03959.8 OAJ32086.1 - 0.027 13.8 0.0 0.15 11.4 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Lipase_3 PF01764.20 OAJ32086.1 - 0.094 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) LIP PF03583.9 OAJ32087.1 - 1.7e-55 188.2 0.1 2.4e-55 187.7 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 OAJ32087.1 - 2.5e-08 34.0 0.5 4.9e-08 33.1 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ32087.1 - 5.3e-08 32.7 0.1 1e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ32087.1 - 0.035 13.3 0.1 8.5 5.5 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Cutinase PF01083.17 OAJ32087.1 - 0.048 13.3 0.3 0.097 12.3 0.0 1.6 2 0 0 2 2 2 0 Cutinase Abhydrolase_1 PF00561.15 OAJ32087.1 - 0.049 13.1 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold EI24 PF07264.6 OAJ32090.1 - 0.015 14.6 8.5 0.034 13.5 5.9 1.7 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF3270 PF11674.3 OAJ32090.1 - 0.1 12.5 1.3 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) TP53IP5 PF15331.1 OAJ32091.1 - 2.2 8.1 7.7 3.3 7.5 1.2 2.3 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 ABC_membrane PF00664.18 OAJ32092.1 - 5.8e-38 130.8 14.0 1.5e-25 90.1 4.3 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ32092.1 - 1.5e-37 128.9 0.0 1.5e-29 103.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAJ32092.1 - 2e-08 33.7 1.1 0.00057 19.1 0.0 3.4 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 OAJ32092.1 - 1.1e-06 28.7 2.8 0.00021 21.3 0.4 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 OAJ32092.1 - 4.1e-06 27.2 0.2 0.061 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAJ32092.1 - 4.5e-06 26.1 0.7 0.073 12.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 OAJ32092.1 - 0.00065 19.1 1.5 0.023 14.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAJ32092.1 - 0.001 19.1 0.2 0.17 12.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 OAJ32092.1 - 0.0011 17.9 0.1 0.16 10.8 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 OAJ32092.1 - 0.0012 18.4 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 OAJ32092.1 - 0.0012 18.8 0.0 1 9.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 OAJ32092.1 - 0.0016 18.8 0.0 3.6 8.1 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 OAJ32092.1 - 0.0026 17.6 0.0 0.59 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 OAJ32092.1 - 0.0032 17.4 0.0 0.37 10.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 OAJ32092.1 - 0.0045 16.8 0.3 0.031 14.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_14 PF13173.1 OAJ32092.1 - 0.0097 15.8 0.1 1.3 8.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 OAJ32092.1 - 0.0098 15.0 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 OAJ32092.1 - 0.0099 15.5 0.1 0.85 9.2 0.0 2.7 2 1 0 2 2 2 1 Archaeal ATPase Dynamin_N PF00350.18 OAJ32092.1 - 0.013 15.2 0.1 1.3 8.8 0.0 2.6 2 0 0 2 2 2 0 Dynamin family ABC_ATPase PF09818.4 OAJ32092.1 - 0.026 13.1 1.3 0.9 8.0 0.0 2.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_10 PF12846.2 OAJ32092.1 - 0.03 13.7 0.8 1.2 8.5 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain AAA_18 PF13238.1 OAJ32092.1 - 0.067 13.4 0.5 0.79 10.0 0.0 2.9 4 0 0 4 4 3 0 AAA domain TrwB_AAD_bind PF10412.4 OAJ32092.1 - 0.079 11.5 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.1 OAJ32092.1 - 0.11 13.2 0.1 3.3 8.5 0.0 3.3 4 0 0 4 4 3 0 AAA domain MobB PF03205.9 OAJ32092.1 - 0.14 11.8 0.1 5.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Abhydrolase_6 PF12697.2 OAJ32093.1 - 6.3e-30 104.7 0.0 1e-29 104.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ32093.1 - 2.2e-15 56.6 0.0 3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAJ32093.1 - 1.7e-09 37.6 0.0 2.6e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 OAJ32093.1 - 2e-09 37.3 0.0 6.4e-08 32.4 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAJ32093.1 - 5e-05 23.0 0.0 0.00013 21.7 0.0 1.7 2 0 0 2 2 1 1 Putative lysophospholipase Thioesterase PF00975.15 OAJ32093.1 - 0.0017 18.6 0.0 0.0026 18.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydro_lipase PF04083.11 OAJ32093.1 - 0.002 17.4 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 2 Partial alpha/beta-hydrolase lipase region Chlorophyllase PF07224.6 OAJ32093.1 - 0.0032 16.3 0.0 0.0045 15.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Peptidase_S9 PF00326.16 OAJ32093.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF676 PF05057.9 OAJ32093.1 - 0.017 14.4 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.15 OAJ32093.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.6 1 1 0 1 1 1 0 Putative esterase LCAT PF02450.10 OAJ32093.1 - 0.031 13.2 0.0 0.046 12.6 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.8 OAJ32093.1 - 0.044 13.3 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 OAJ32093.1 - 0.068 11.4 0.0 2.8 6.1 0.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.2 OAJ32093.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF1343 PF07075.6 OAJ32093.1 - 0.22 10.3 0.2 0.45 9.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1343) WD40 PF00400.27 OAJ32095.1 - 3.4e-47 156.7 26.8 1.4e-09 37.4 0.2 8.7 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 OAJ32095.1 - 1.1e-10 41.0 0.2 2.5e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 OAJ32095.1 - 5e-09 34.8 8.2 0.6 8.1 0.1 5.3 2 1 3 5 5 5 5 Nucleoporin Nup120/160 PQQ_3 PF13570.1 OAJ32095.1 - 7.2e-05 22.9 6.0 4.4 7.6 0.0 6.2 5 1 1 6 6 6 2 PQQ-like domain F-box PF00646.28 OAJ32095.1 - 0.0003 20.3 0.1 0.00062 19.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain Abhydrolase_5 PF12695.2 OAJ32096.1 - 0.00017 21.3 0.0 0.00035 20.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAJ32096.1 - 0.023 14.2 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 OAJ32096.1 - 0.024 14.4 0.0 0.044 13.6 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_L14 PF00238.14 OAJ32096.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L14p/L23e Ndr PF03096.9 OAJ32096.1 - 0.17 10.3 0.0 0.47 8.8 0.0 1.6 2 0 0 2 2 2 0 Ndr family FTHFS PF01268.14 OAJ32097.1 - 1.3e-241 802.5 0.1 2.8e-241 801.3 0.0 1.5 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 OAJ32097.1 - 2.4e-63 211.9 0.7 2.4e-63 211.9 0.5 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 OAJ32097.1 - 2.3e-29 101.8 0.0 6.8e-29 100.2 0.0 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Prefoldin PF02996.12 OAJ32097.1 - 0.24 11.0 0.3 0.66 9.6 0.0 1.8 2 0 0 2 2 2 0 Prefoldin subunit Endotoxin_N PF03945.9 OAJ32098.1 - 1.8 7.8 0.1 3.1 7.1 0.1 1.2 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain HIG_1_N PF04588.8 OAJ32099.1 - 7.3e-19 67.2 0.3 1.1e-18 66.7 0.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region PGA2 PF07543.7 OAJ32099.1 - 0.15 11.8 2.7 0.22 11.3 1.9 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 CAF-1_p150 PF11600.3 OAJ32099.1 - 2.4 7.4 7.9 0.24 10.7 0.6 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PCNA_N PF00705.13 OAJ32100.1 - 9e-51 170.6 3.5 2.6e-50 169.2 0.9 2.2 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 OAJ32100.1 - 7.1e-43 145.5 0.0 3.7e-22 78.5 0.1 2.4 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 OAJ32100.1 - 4.3e-08 32.2 0.7 1.6e-06 27.0 0.5 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 OAJ32100.1 - 2.1e-05 23.7 0.0 8.3e-05 21.8 0.0 1.9 1 1 0 1 1 1 1 Rad9 Myc_N PF01056.13 OAJ32100.1 - 0.026 13.6 1.7 0.037 13.1 1.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region BSP_II PF05432.6 OAJ32100.1 - 0.041 13.1 3.2 0.066 12.4 2.2 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 OAJ32100.1 - 0.053 13.0 1.9 0.095 12.2 1.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 OAJ32100.1 - 0.078 13.2 4.8 0.16 12.2 3.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 OAJ32100.1 - 0.098 12.9 4.0 0.22 11.7 2.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LRS4 PF10422.4 OAJ32100.1 - 0.27 10.5 3.7 0.6 9.4 0.7 2.0 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 Metallopep PF12044.3 OAJ32101.1 - 1.6e-83 280.5 0.0 1.4e-35 122.5 0.0 3.1 3 0 0 3 3 3 3 Putative peptidase family Jacalin PF01419.12 OAJ32101.1 - 3.5e-19 68.9 0.0 0.0027 17.5 0.0 4.9 5 0 0 5 5 5 4 Jacalin-like lectin domain Peptidase_M66 PF10462.4 OAJ32101.1 - 0.0076 15.1 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase M66 Adeno_PX PF05829.7 OAJ32101.1 - 0.1 12.1 0.2 62 3.1 0.0 3.4 3 0 0 3 3 3 0 Adenovirus late L2 mu core protein (Protein X) PARP PF00644.15 OAJ32103.1 - 1.9e-15 56.8 0.1 9.4e-10 38.2 0.0 2.9 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain FdhE PF04216.7 OAJ32103.1 - 0.0092 15.7 0.1 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation Fasciclin PF02469.17 OAJ32103.1 - 0.021 14.8 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Fasciclin domain zf-HC5HC2H PF13771.1 OAJ32103.1 - 0.65 10.1 5.5 8.2 6.6 0.2 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain CNH PF00780.17 OAJ32104.1 - 8.4e-36 123.7 0.0 1.5e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 OAJ32104.1 - 4.4e-24 85.3 0.2 7.3e-24 84.6 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 OAJ32104.1 - 2.3e-05 24.0 0.0 5.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_5 PF15405.1 OAJ32104.1 - 0.0053 16.7 0.0 0.018 14.9 0.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PARP PF00644.15 OAJ32105.1 - 6.2e-08 32.3 0.1 9.8e-07 28.4 0.0 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.6 OAJ32106.1 - 1.9e-18 66.7 0.2 2.3e-18 66.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.6 OAJ32106.1 - 0.0028 17.1 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Bacteriophage protein GP30.3 Dfp1_Him1_M PF08630.5 OAJ32107.1 - 4.4e-30 104.0 0.0 7.6e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 OAJ32107.1 - 1.3e-21 75.9 1.0 2.8e-21 74.9 0.7 1.6 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 OAJ32107.1 - 0.0017 18.4 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 OAJ32107.1 - 0.008 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain SSF PF00474.12 OAJ32108.1 - 8.8e-21 74.0 20.1 1.5e-20 73.2 13.9 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Fungal_trans PF04082.13 OAJ32109.1 - 0.0048 15.7 2.1 0.0076 15.1 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ32109.1 - 0.053 13.4 3.5 0.089 12.7 2.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.1 OAJ32110.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ32110.1 - 6.5e-11 42.0 0.0 1.1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAJ32110.1 - 1.8e-08 34.1 0.0 2.9e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAJ32110.1 - 6e-07 29.3 0.0 9.6e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 OAJ32110.1 - 8.2e-06 25.9 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 OAJ32110.1 - 1.7e-05 25.2 0.0 3.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 OAJ32110.1 - 0.0073 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin RNA_pol_I_A49 PF06870.7 OAJ32110.1 - 0.073 11.6 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor rve PF00665.21 OAJ32111.1 - 1e-14 54.6 0.0 1.4e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ32111.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Ish1 PF10281.4 OAJ32111.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein UBN2_2 PF14227.1 OAJ32112.1 - 1.2e-16 60.2 0.1 1.8e-16 59.7 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ32112.1 - 2.8e-11 43.2 0.2 4.3e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAJ32112.1 - 3.2e-07 29.8 0.0 6.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_3 PF14244.1 OAJ32112.1 - 7.2e-06 25.6 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 OAJ32112.1 - 0.00015 21.0 0.0 0.0003 20.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) RVP PF00077.15 OAJ32112.1 - 0.004 17.0 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.18 OAJ32112.1 - 0.0057 16.5 4.5 0.014 15.3 3.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ32112.1 - 0.14 11.7 3.2 0.17 11.3 1.1 1.9 2 0 0 2 2 2 0 Zinc knuckle Mre11_DNA_bind PF04152.9 OAJ32113.1 - 1.2e-43 148.9 5.1 1.2e-43 148.9 3.5 1.8 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 OAJ32113.1 - 6.5e-22 77.9 0.5 9.6e-22 77.3 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase S-AdoMet_synt_C PF02773.11 OAJ32114.1 - 3.9e-75 250.1 0.2 7.4e-75 249.2 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 OAJ32114.1 - 1.8e-48 163.3 0.0 3.2e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 OAJ32114.1 - 6.8e-44 148.1 0.1 1.3e-43 147.2 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Inhibitor_I9 PF05922.11 OAJ32115.1 - 3.6e-10 40.2 0.1 1.3e-09 38.5 0.1 1.7 1 1 0 1 1 1 1 Peptidase inhibitor I9 Acyl-CoA_dh_1 PF00441.19 OAJ32116.1 - 9.7e-43 145.8 1.0 1.7e-42 145.0 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAJ32116.1 - 1.8e-33 115.4 0.0 3.1e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ32116.1 - 4.1e-19 67.8 0.1 9.9e-19 66.6 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 OAJ32116.1 - 1.4e-16 60.9 0.5 2.4e-16 60.1 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CPSase_L_D2 PF02786.12 OAJ32117.1 - 8.7e-73 244.0 0.0 8.7e-72 240.8 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 OAJ32117.1 - 1.5e-43 147.3 0.0 4.1e-43 145.9 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 OAJ32117.1 - 1.9e-35 121.0 0.0 4.1e-35 120.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 OAJ32117.1 - 5.3e-15 55.6 0.0 1.2e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 OAJ32117.1 - 6.9e-14 51.2 2.2 1.4e-13 50.2 1.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 OAJ32117.1 - 5.8e-12 44.9 0.0 7.8e-11 41.2 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 OAJ32117.1 - 1.2e-09 37.9 0.0 2.4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 OAJ32117.1 - 4.1e-06 26.3 0.4 1.2e-05 24.8 0.2 1.8 1 1 0 1 1 1 1 Biotin-lipoyl like ATP-grasp PF02222.17 OAJ32117.1 - 4.7e-06 26.0 0.0 9.9e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 OAJ32117.1 - 0.0017 18.6 2.5 0.86 9.9 0.0 2.9 3 0 0 3 3 2 2 HlyD family secretion protein DUF3322 PF11795.3 OAJ32117.1 - 0.007 16.0 0.5 0.014 14.9 0.3 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) GARS_A PF01071.14 OAJ32117.1 - 0.0077 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 OAJ32117.1 - 0.046 13.1 0.0 0.34 10.3 0.0 2.1 1 1 0 1 1 1 0 RimK-like ATP-grasp domain P53_tetramer PF07710.6 OAJ32117.1 - 0.1 11.7 0.1 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 P53 tetramerisation motif DHFR_1 PF00186.14 OAJ32118.1 - 7.6e-27 93.8 0.0 2.7e-23 82.3 0.0 2.5 2 1 0 2 2 2 2 Dihydrofolate reductase Spc7 PF08317.6 OAJ32119.1 - 9e-09 34.4 4.9 1.4e-08 33.8 3.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein IncA PF04156.9 OAJ32119.1 - 0.064 12.8 8.5 0.14 11.7 5.9 1.6 1 0 0 1 1 1 0 IncA protein Snf7 PF03357.16 OAJ32120.1 - 1.2e-31 109.3 14.6 2e-31 108.6 10.1 1.4 1 0 0 1 1 1 1 Snf7 TIP39 PF14980.1 OAJ32120.1 - 0.67 9.6 3.7 0.43 10.2 0.9 1.9 2 0 0 2 2 2 0 TIP39 peptide Brix PF04427.13 OAJ32121.1 - 9.3e-37 126.5 0.0 1.4e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.7 OAJ32121.1 - 0.0038 15.2 2.8 0.0038 15.2 1.9 2.2 2 0 0 2 2 2 2 Nop14-like family Spt5_N PF11942.3 OAJ32121.1 - 0.11 13.1 26.0 0.24 12.0 0.7 3.2 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DUF2890 PF11081.3 OAJ32121.1 - 0.12 12.3 10.5 0.46 10.5 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 OAJ32121.1 - 1.9 6.4 21.7 0.93 7.4 7.7 2.2 2 0 0 2 2 2 0 CDC45-like protein Sporozoite_P67 PF05642.6 OAJ32121.1 - 2.5 5.8 10.8 0.35 8.6 1.9 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen BNIP2 PF12496.3 OAJ32121.1 - 4.3 7.5 10.5 4.3 7.5 1.5 2.4 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Serinc PF03348.10 OAJ32122.1 - 1.6e-142 475.2 4.0 2.1e-142 474.8 2.8 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) Nop14 PF04147.7 OAJ32124.1 - 0.032 12.1 3.5 0.084 10.7 2.4 1.7 1 0 0 1 1 1 0 Nop14-like family BNIP3 PF06553.7 OAJ32124.1 - 6.5 6.0 10.7 0.1 11.9 1.8 2.0 2 0 0 2 2 2 0 BNIP3 NDK PF00334.14 OAJ32125.1 - 1.5e-54 183.3 0.0 1.7e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 OAJ32125.1 - 0.0099 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Photosystem I reaction centre subunit IX / PsaJ p450 PF00067.17 OAJ32128.1 - 1.1e-67 228.5 0.0 3.9e-53 180.6 0.0 1.9 2 0 0 2 2 2 2 Cytochrome P450 Ribosomal_L13 PF00572.13 OAJ32129.1 - 1.9e-24 86.1 0.0 3.2e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 Kua-UEV1_localn PF10520.4 OAJ32129.1 - 0.11 12.1 0.3 0.15 11.6 0.2 1.2 1 0 0 1 1 1 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain Ribosomal_L32e PF01655.13 OAJ32130.1 - 1.2e-45 154.0 2.0 1.4e-45 153.8 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 DUF1771 PF08590.5 OAJ32131.1 - 2e-21 75.7 8.7 4.9e-21 74.4 6.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 OAJ32131.1 - 7.1e-17 61.3 0.2 2.2e-16 59.8 0.1 1.9 1 0 0 1 1 1 1 Smr domain PAT1 PF09770.4 OAJ32131.1 - 2.6 6.1 15.2 3.4 5.8 10.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 OAJ32131.1 - 9 4.3 25.8 10 4.1 17.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RNB PF00773.14 OAJ32135.1 - 5.2e-54 183.7 0.0 7.5e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 RNB domain MARVEL PF01284.18 OAJ32137.1 - 7.9e-06 25.7 9.8 1.3e-05 25.0 6.8 1.4 1 1 0 1 1 1 1 Membrane-associating domain Zip PF02535.17 OAJ32137.1 - 0.0001 21.4 0.0 0.00012 21.1 0.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Nup54 PF13874.1 OAJ32138.1 - 3.8e-21 75.2 3.8 4.3e-19 68.5 0.0 2.8 3 0 0 3 3 3 2 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 OAJ32138.1 - 1e-06 28.9 43.6 1e-06 28.9 30.2 4.2 2 2 1 3 3 3 2 Nucleoporin FG repeat region DUF1748 PF08520.5 OAJ32139.1 - 2.6e-19 68.6 0.0 2.9e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) MmgE_PrpD PF03972.9 OAJ32140.1 - 1.2e-147 491.6 0.6 2e-147 490.9 0.4 1.3 1 0 0 1 1 1 1 MmgE/PrpD family Filament_head PF04732.9 OAJ32142.1 - 7.5 7.3 15.5 11 6.7 6.6 2.5 2 1 0 2 2 2 0 Intermediate filament head (DNA binding) region EF-hand_7 PF13499.1 OAJ32144.1 - 2.3e-08 34.0 0.1 3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 OAJ32144.1 - 2.4e-07 29.5 0.1 9.6e-06 24.5 0.0 2.6 2 1 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 OAJ32144.1 - 1e-06 28.0 0.3 5.8e-06 25.7 0.0 2.2 2 1 1 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 OAJ32144.1 - 0.0043 16.3 0.2 0.022 14.0 0.0 2.4 2 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 OAJ32144.1 - 0.0044 16.5 1.3 0.089 12.4 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair DUF4160 PF13711.1 OAJ32144.1 - 0.16 11.7 0.8 3.1 7.7 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4160) DUF2782 PF11191.3 OAJ32145.1 - 0.029 14.3 1.2 0.11 12.4 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) MIP-T3 PF10243.4 OAJ32145.1 - 1.2 7.4 19.8 2.1 6.6 13.7 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 GCIP PF13324.1 OAJ32146.1 - 0.0059 15.8 7.7 0.018 14.2 4.6 2.3 2 1 0 2 2 2 1 Grap2 and cyclin-D-interacting FAM176 PF14851.1 OAJ32146.1 - 1.4 8.5 4.5 4.8 6.8 3.1 1.9 1 0 0 1 1 1 0 FAM176 family RRN3 PF05327.6 OAJ32146.1 - 4.8 5.1 4.9 7.3 4.5 3.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GPI2 PF06432.6 OAJ32147.1 - 1.8e-70 237.4 2.1 2.9e-62 210.5 0.0 2.1 2 0 0 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase Tic20 PF09685.5 OAJ32147.1 - 0.21 11.6 0.0 0.21 11.6 0.0 3.3 4 0 0 4 4 4 0 Tic20-like protein RRM_1 PF00076.17 OAJ32148.1 - 2.1e-17 62.5 0.0 3.2e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ32148.1 - 5.3e-16 58.3 0.0 8e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ32148.1 - 3.9e-08 33.0 0.0 5.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNARE PF05739.14 OAJ32149.1 - 2e-07 30.5 1.6 2e-07 30.5 1.1 3.6 4 0 0 4 4 4 1 SNARE domain Polysacc_deac_2 PF04748.8 OAJ32149.1 - 0.15 11.0 3.6 0.38 9.7 0.1 2.5 3 0 0 3 3 3 0 Divergent polysaccharide deacetylase DUF4211 PF13926.1 OAJ32150.1 - 0.00037 19.9 0.0 0.0008 18.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) OsmC PF02566.14 OAJ32151.1 - 1.2e-18 67.1 0.0 2.1e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 OsmC-like protein AAA PF00004.24 OAJ32152.1 - 0.00051 20.2 0.3 0.0036 17.5 0.1 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 OAJ32152.1 - 0.047 12.5 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein TIP49 PF06068.8 OAJ32152.1 - 0.19 10.4 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus DUF2638 PF10937.3 OAJ32154.1 - 2.6e-08 34.8 3.4 4.3e-08 34.1 2.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2638) Pkinase PF00069.20 OAJ32155.1 - 1.4e-09 37.5 0.0 3.1e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ32155.1 - 0.0028 16.7 0.0 0.061 12.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Adenylsucc_synt PF00709.16 OAJ32157.1 - 5.6e-162 539.1 0.0 6.3e-162 539.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF663 PF04950.7 OAJ32158.1 - 1.9e-80 269.9 0.3 4.9e-80 268.6 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 OAJ32158.1 - 1.1e-29 101.7 0.0 3.3e-29 100.2 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 OAJ32158.1 - 2.2e-06 27.2 0.0 0.00014 21.3 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 OAJ32158.1 - 5.2e-06 26.5 0.1 2e-05 24.6 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ32158.1 - 5.5e-05 23.3 0.0 0.00019 21.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 OAJ32158.1 - 0.00021 20.9 0.1 0.00057 19.6 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 OAJ32158.1 - 0.00024 20.7 0.2 0.00083 19.0 0.0 1.9 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.4 OAJ32158.1 - 0.0011 18.4 0.1 0.0038 16.7 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 OAJ32158.1 - 0.0012 19.3 0.9 0.0041 17.6 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 OAJ32158.1 - 0.0018 19.0 0.0 0.0018 19.0 0.0 3.3 3 2 0 3 3 1 1 AAA domain AAA_25 PF13481.1 OAJ32158.1 - 0.0045 16.4 0.0 0.02 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 OAJ32158.1 - 0.0054 16.9 0.6 0.011 15.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 OAJ32158.1 - 0.017 15.0 2.3 0.021 14.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 OAJ32158.1 - 0.026 14.6 0.0 0.065 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 OAJ32158.1 - 0.03 14.6 1.4 0.06 13.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.18 OAJ32158.1 - 0.04 13.8 0.1 0.13 12.2 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 OAJ32158.1 - 0.064 13.1 0.0 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 OAJ32158.1 - 0.065 12.9 0.2 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 NTPase DUF258 PF03193.11 OAJ32158.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.14 OAJ32158.1 - 0.36 10.2 2.0 0.3 10.5 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF202 PF02656.10 OAJ32159.1 - 6.5e-20 71.1 2.9 6.5e-20 71.1 2.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF202) DUF2157 PF09925.4 OAJ32159.1 - 0.15 11.6 3.2 1.6 8.3 0.0 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) MAPEG PF01124.13 OAJ32160.1 - 5.2e-26 90.7 0.7 6.1e-26 90.5 0.5 1.1 1 0 0 1 1 1 1 MAPEG family Peptidase_M3 PF01432.15 OAJ32160.1 - 0.29 10.1 0.9 7.3 5.4 0.3 2.0 1 1 1 2 2 2 0 Peptidase family M3 MFS_1 PF07690.11 OAJ32161.1 - 2.6e-35 121.8 11.6 2.6e-35 121.8 8.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ32161.1 - 2.5e-07 29.6 18.4 5.9e-07 28.4 4.1 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 OAJ32161.1 - 0.0029 15.8 0.9 0.0049 15.1 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Nuc_H_symport PF03825.11 OAJ32161.1 - 0.011 14.5 7.5 0.024 13.4 0.5 2.4 2 0 0 2 2 2 0 Nucleoside H+ symporter MFS_3 PF05977.8 OAJ32161.1 - 1.1 7.3 8.6 0.18 9.8 0.8 2.4 2 0 0 2 2 2 0 Transmembrane secretion effector Asp PF00026.18 OAJ32162.1 - 6.6e-64 216.1 0.1 8.2e-64 215.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ32162.1 - 1.4e-06 28.3 0.3 3.3e-06 27.1 0.2 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAJ32162.1 - 2.7e-06 27.7 1.8 0.0013 19.1 0.0 3.4 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 OAJ32162.1 - 0.023 14.5 0.5 0.076 12.8 0.0 2.1 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease adh_short PF00106.20 OAJ32163.1 - 9.3e-32 110.2 1.2 1.7e-31 109.3 0.8 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ32163.1 - 7.4e-15 55.0 4.7 6.3e-14 52.0 2.3 2.7 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 OAJ32163.1 - 1.2e-10 41.5 0.0 1.7e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAJ32163.1 - 1.3e-05 24.8 0.2 8.6e-05 22.0 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ32163.1 - 0.00012 22.1 0.9 0.00028 20.9 0.6 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAJ32163.1 - 0.00045 19.0 0.3 0.00066 18.4 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 OAJ32163.1 - 0.0025 16.7 0.1 0.0037 16.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Urocanase PF01175.13 OAJ32163.1 - 0.0077 14.3 0.0 0.01 13.9 0.0 1.1 1 0 0 1 1 1 1 Urocanase FAD_binding_3 PF01494.14 OAJ32163.1 - 0.019 14.0 0.2 0.03 13.3 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 OAJ32163.1 - 0.043 13.4 0.2 0.085 12.4 0.2 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IncA PF04156.9 OAJ32163.1 - 0.093 12.3 1.0 0.26 10.8 0.4 1.9 2 0 0 2 2 2 0 IncA protein ELFV_dehydrog PF00208.16 OAJ32163.1 - 0.13 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ada_Zn_binding PF02805.11 OAJ32164.1 - 8.6e-20 70.1 7.6 1.6e-19 69.2 5.3 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 OAJ32164.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family ADIP PF11559.3 OAJ32165.1 - 6.9e-19 68.2 4.4 1.2e-18 67.4 3.0 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Myosin_tail_1 PF01576.14 OAJ32165.1 - 0.0011 16.8 5.7 0.0015 16.4 4.0 1.1 1 0 0 1 1 1 1 Myosin tail CCDC144C PF14915.1 OAJ32165.1 - 0.0033 16.3 7.2 0.0052 15.7 5.0 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region ERM PF00769.14 OAJ32165.1 - 0.015 14.8 8.0 0.031 13.8 5.6 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF2360 PF10152.4 OAJ32165.1 - 1.6 9.0 4.6 15 5.8 3.2 2.2 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DivIVA PF05103.8 OAJ32165.1 - 10 6.2 9.5 2.9 7.9 3.7 2.0 2 0 0 2 2 2 0 DivIVA protein HSF_DNA-bind PF00447.12 OAJ32166.1 - 5.5e-34 116.4 0.1 5.5e-34 116.4 0.0 2.6 2 0 0 2 2 2 1 HSF-type DNA-binding FA_desaturase PF00487.19 OAJ32167.1 - 2.9e-27 95.7 24.0 8.4e-27 94.2 16.6 1.7 1 1 0 1 1 1 1 Fatty acid desaturase Na_H_Exchanger PF00999.16 OAJ32169.1 - 3.5e-40 137.6 19.3 4.6e-40 137.3 13.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family LsmAD PF06741.8 OAJ32170.1 - 1.6e-24 85.7 0.9 3.3e-24 84.7 0.6 1.6 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 OAJ32170.1 - 7.2e-10 38.6 0.0 1.5e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain L31 PF09784.4 OAJ32171.1 - 9.9e-42 141.2 1.0 1.1e-41 141.0 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Glyco_hydro_18 PF00704.23 OAJ32172.1 - 1.8e-89 300.5 0.1 2.2e-89 300.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Metallophos PF00149.23 OAJ32174.1 - 9.3e-30 103.5 0.0 1.2e-28 99.8 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 OAJ32174.1 - 1.6e-20 72.4 1.0 1.7e-14 53.2 0.1 2.6 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 OAJ32174.1 - 2.9e-14 51.9 0.9 2.5e-06 26.8 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ32174.1 - 5.4e-09 35.2 3.3 0.0021 17.8 0.0 4.1 5 0 0 5 5 5 3 Tetratricopeptide repeat PPP5 PF08321.7 OAJ32174.1 - 7.1e-09 35.5 0.0 2.5e-05 24.2 0.0 2.4 1 1 1 2 2 2 2 PPP5 TPR repeat region TPR_17 PF13431.1 OAJ32174.1 - 0.00075 19.5 0.2 0.04 14.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ32174.1 - 0.0089 16.6 1.4 0.11 13.2 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ32174.1 - 0.0094 15.7 0.6 0.043 13.6 0.0 2.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 OAJ32174.1 - 0.019 14.0 0.0 0.68 8.9 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ32174.1 - 0.096 13.3 0.3 5.4 7.9 0.0 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat RAI1 PF08652.6 OAJ32175.1 - 7.9e-19 67.2 0.0 1.9e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease GATA PF00320.22 OAJ32176.1 - 1.5e-14 53.0 8.5 3.2e-14 51.9 5.9 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 OAJ32176.1 - 0.011 15.0 1.5 0.022 14.0 1.0 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Zip PF02535.17 OAJ32176.1 - 0.033 13.1 8.4 0.051 12.5 5.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter zf-ribbon_3 PF13248.1 OAJ32176.1 - 0.083 12.1 1.1 0.18 11.0 0.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain RRN7 PF11781.3 OAJ32176.1 - 0.29 10.6 1.2 0.59 9.6 0.8 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Synaptobrevin PF00957.16 OAJ32177.1 - 1.4e-14 53.4 1.3 1.4e-14 53.4 0.9 1.8 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.1 OAJ32177.1 - 1.9e-14 52.9 0.0 6.5e-14 51.2 0.0 1.9 2 0 0 2 2 2 1 Regulated-SNARE-like domain Methyltransf_12 PF08242.7 OAJ32178.1 - 1.8e-06 28.3 0.0 3.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ32178.1 - 9.7e-06 26.1 0.0 1.7e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ32178.1 - 4.7e-05 23.1 0.0 0.00017 21.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ32178.1 - 0.00011 22.5 0.0 0.00021 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ32178.1 - 0.0019 17.8 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ32178.1 - 0.032 14.5 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SH3BGR PF04908.10 OAJ32179.1 - 3.5e-16 58.9 0.0 4.5e-08 32.9 0.0 3.2 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 OAJ32179.1 - 0.62 10.0 1.5 59 3.7 0.0 3.5 4 0 0 4 4 4 0 Glutaredoxin DUF500 PF04366.7 OAJ32180.1 - 5.1e-40 135.8 0.0 1.1e-39 134.7 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF500) APC_CDC26 PF10471.4 OAJ32180.1 - 0.00038 21.1 6.7 0.023 15.4 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex APC subunit 1 WD40 PF00400.27 OAJ32182.1 - 0.00045 19.9 2.9 0.0043 16.8 0.0 3.4 4 0 0 4 4 4 1 WD domain, G-beta repeat Ion_trans PF00520.26 OAJ32183.1 - 1.5e-103 344.3 81.6 4.6e-34 117.4 8.2 5.2 5 0 0 5 5 5 4 Ion transport protein EF-hand_1 PF00036.27 OAJ32183.1 - 0.015 14.5 0.0 0.041 13.2 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 OAJ32183.1 - 0.032 14.1 0.0 0.13 12.2 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain HSP70 PF00012.15 OAJ32184.1 - 2.2e-270 897.7 8.5 2.6e-270 897.5 5.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAJ32184.1 - 6.6e-16 57.8 0.5 1.3e-14 53.5 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 OAJ32184.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 OAJ32184.1 - 0.011 14.9 0.2 0.034 13.2 0.2 1.9 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FtsA PF14450.1 OAJ32184.1 - 0.013 15.3 3.8 4.1 7.2 0.2 3.4 2 2 0 2 2 2 0 Cell division protein FtsA NeA_P2 PF12312.3 OAJ32185.1 - 2.2 7.4 7.8 0.86 8.7 0.6 2.1 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein SMN PF06003.7 OAJ32185.1 - 8.6 5.3 8.9 10 5.1 6.2 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Cupin_5 PF06172.6 OAJ32186.1 - 5.7e-15 55.4 0.0 5.4e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily (DUF985) Ribosomal_L6 PF00347.18 OAJ32187.1 - 5e-24 84.5 3.1 2.5e-11 43.9 0.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 TB2_DP1_HVA22 PF03134.14 OAJ32190.1 - 1.2e-21 76.2 8.5 7.3e-19 67.3 3.1 2.3 2 0 0 2 2 2 2 TB2/DP1, HVA22 family CHD5 PF04420.9 OAJ32191.1 - 3e-39 134.2 0.0 3.4e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 CHD5-like protein Rubredoxin PF00301.15 OAJ32192.1 - 0.057 13.3 1.4 2.4 8.1 0.1 2.6 2 0 0 2 2 2 0 Rubredoxin FYVE_2 PF02318.11 OAJ32192.1 - 0.19 11.6 2.3 1.2 9.1 0.1 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger DZR PF12773.2 OAJ32192.1 - 0.38 10.6 3.6 0.61 9.9 0.2 2.1 2 0 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 OAJ32192.1 - 3.7 7.4 6.4 18 5.2 4.4 2.0 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-AD PF07776.10 OAJ32192.1 - 3.8 7.5 5.6 1.4 8.9 0.3 2.0 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) SIR2 PF02146.12 OAJ32193.1 - 6.4e-54 182.3 0.0 9.9e-54 181.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family F-box PF00646.28 OAJ32195.1 - 0.0046 16.5 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ32195.1 - 0.034 13.8 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like Imm18 PF15566.1 OAJ32195.1 - 0.066 12.5 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 18 Tir_receptor_C PF07489.6 OAJ32196.1 - 0.064 13.0 4.9 0.1 12.3 3.4 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF3439 PF11921.3 OAJ32196.1 - 0.12 12.1 5.5 0.22 11.2 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Myosin_HC-like PF07058.6 OAJ32197.1 - 0.076 12.0 0.2 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Myosin II heavy chain-like Dppa2_A PF14049.1 OAJ32197.1 - 0.086 12.7 1.0 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates 4HBT_3 PF13622.1 OAJ32198.1 - 4.2e-41 141.3 0.0 6.5e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 OAJ32198.1 - 9.7e-22 77.0 0.0 1.6e-18 66.6 0.0 2.9 2 1 0 2 2 2 2 Acyl-CoA thioesterase Dus PF01207.12 OAJ32199.1 - 2e-47 161.5 0.0 2.9e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Vps51 PF08700.6 OAJ32200.1 - 8.5e-23 80.0 0.1 1.8e-22 78.9 0.0 1.5 1 1 1 2 2 2 1 Vps51/Vps67 COG5 PF10392.4 OAJ32200.1 - 0.00085 19.2 0.4 0.0012 18.8 0.2 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.7 OAJ32200.1 - 0.0019 16.7 0.5 0.0025 16.3 0.3 1.1 1 0 0 1 1 1 1 Dor1-like family DUF3086 PF11285.3 OAJ32200.1 - 0.013 14.2 0.3 0.017 13.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) FlgN PF05130.7 OAJ32200.1 - 0.075 13.2 0.3 0.11 12.7 0.2 1.2 1 0 0 1 1 1 0 FlgN protein Vps52 PF04129.7 OAJ32200.1 - 0.15 10.5 0.1 0.18 10.2 0.1 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family Chorion_3 PF05387.6 OAJ32200.1 - 0.58 9.5 4.3 0.77 9.1 3.0 1.3 1 0 0 1 1 1 0 Chorion family 3 Patched PF02460.13 OAJ32201.1 - 2.1e-63 214.5 10.0 2e-39 135.2 0.2 2.9 3 1 0 3 3 3 2 Patched family Sterol-sensing PF12349.3 OAJ32201.1 - 4.4e-43 146.3 13.6 2.6e-23 82.1 0.2 3.2 4 0 0 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 OAJ32201.1 - 0.00032 18.2 1.2 0.00048 17.7 0.8 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family ArfGap PF01412.13 OAJ32202.1 - 6.2e-40 135.6 1.4 8.9e-40 135.1 0.9 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Peptidase_S8 PF00082.17 OAJ32203.1 - 9.9e-48 162.7 12.2 1.6e-47 162.0 8.5 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 OAJ32203.1 - 4.6e-12 46.3 0.2 1.2e-11 45.0 0.2 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 BRE1 PF08647.6 OAJ32204.1 - 1.1e-15 57.3 10.2 1.1e-15 57.3 7.1 7.1 5 3 3 8 8 8 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 OAJ32204.1 - 7.8e-08 32.2 12.5 1.4e-07 31.4 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ32204.1 - 1.1e-06 28.2 13.9 1.9e-06 27.4 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 OAJ32204.1 - 2.7e-06 27.0 2.9 4.9e-06 26.2 2.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 OAJ32204.1 - 1.8e-05 24.3 12.1 3.5e-05 23.4 8.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAJ32204.1 - 1.9e-05 24.2 9.4 3.6e-05 23.3 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ32204.1 - 0.00021 21.0 9.9 0.00038 20.2 6.9 1.5 1 0 0 1 1 1 1 Ring finger domain Fez1 PF06818.10 OAJ32204.1 - 0.0009 19.3 17.1 0.0009 19.3 11.9 5.1 4 1 1 5 5 3 1 Fez1 Seryl_tRNA_N PF02403.17 OAJ32204.1 - 0.0086 16.0 4.8 0.0086 16.0 3.3 8.2 5 3 4 10 10 9 1 Seryl-tRNA synthetase N-terminal domain zf-ribbon_3 PF13248.1 OAJ32204.1 - 0.03 13.5 0.2 0.07 12.3 0.2 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zf-rbx1 PF12678.2 OAJ32204.1 - 0.056 13.5 5.4 0.11 12.6 3.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 OAJ32204.1 - 0.059 13.2 10.8 0.037 13.9 6.1 1.7 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.6 OAJ32204.1 - 0.17 11.7 5.1 0.4 10.5 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) UPF0547 PF10571.4 OAJ32204.1 - 0.26 11.0 1.9 0.55 9.9 1.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-RING_UBOX PF13445.1 OAJ32204.1 - 0.29 10.8 6.0 0.76 9.5 4.1 1.8 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.2 OAJ32204.1 - 0.44 10.4 6.2 1.1 9.1 4.3 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-Nse PF11789.3 OAJ32204.1 - 0.72 9.4 4.8 1.6 8.3 3.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Nsp1_C PF05064.8 OAJ32204.1 - 1.5 8.4 18.4 1.7 8.3 4.7 4.1 4 2 0 4 4 4 0 Nsp1-like C-terminal region FlaC_arch PF05377.6 OAJ32204.1 - 3.2 7.7 21.7 2.2 8.2 0.8 6.6 7 1 1 8 8 7 0 Flagella accessory protein C (FlaC) zf-FCS PF06467.9 OAJ32204.1 - 3.3 7.4 6.6 13 5.4 2.9 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-RING_4 PF14570.1 OAJ32204.1 - 7.7 6.1 9.9 24 4.6 6.9 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Per1 PF04080.8 OAJ32205.1 - 6e-91 304.5 0.0 1.1e-90 303.7 0.0 1.4 1 1 0 1 1 1 1 Per1-like Arf PF00025.16 OAJ32206.1 - 2.6e-67 225.4 0.1 3e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 OAJ32206.1 - 4.8e-12 45.2 2.9 9e-07 27.9 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 OAJ32206.1 - 2.7e-09 36.5 0.0 3.6e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 OAJ32206.1 - 3e-08 33.0 0.0 3.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 OAJ32206.1 - 3.1e-07 30.3 0.0 4.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAJ32206.1 - 9.8e-07 29.2 0.0 1.4e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 OAJ32206.1 - 9.8e-07 28.2 0.0 1.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 OAJ32206.1 - 6.3e-05 22.4 0.0 0.0035 16.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 OAJ32206.1 - 0.022 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 OAJ32206.1 - 0.033 15.0 0.2 0.13 13.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAJ32206.1 - 0.034 14.4 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 OAJ32206.1 - 0.04 13.6 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 OAJ32206.1 - 0.091 12.0 0.1 0.27 10.5 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B FTR1 PF03239.9 OAJ32207.1 - 1.5e-54 185.0 4.9 1.5e-34 119.3 2.0 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family Herpes_glycop PF01528.11 OAJ32207.1 - 0.039 12.6 0.1 0.15 10.7 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus glycoprotein M Cu-oxidase_2 PF07731.9 OAJ32208.1 - 6.7e-36 122.8 4.3 3.9e-35 120.3 1.8 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 OAJ32208.1 - 1.2e-35 122.7 0.1 2.4e-32 112.0 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 OAJ32208.1 - 1.1e-26 92.8 5.9 6.9e-24 83.8 0.5 3.7 4 0 0 4 4 4 2 Multicopper oxidase DUF1690 PF07956.6 OAJ32209.1 - 8.9e-14 51.6 2.9 8.9e-14 51.6 2.0 2.1 2 0 0 2 2 2 1 Protein of Unknown function (DUF1690) Rootletin PF15035.1 OAJ32209.1 - 0.027 14.4 11.0 0.67 9.8 7.6 2.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Apolipoprotein PF01442.13 OAJ32209.1 - 0.031 13.7 8.3 1.4 8.3 0.0 2.5 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain GIT1_C PF12205.3 OAJ32209.1 - 0.077 12.8 2.2 0.082 12.7 0.3 2.0 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Tape_meas_lam_C PF09718.5 OAJ32209.1 - 0.65 9.9 10.0 0.24 11.3 1.0 3.2 2 1 1 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF883 PF05957.8 OAJ32209.1 - 1.7 9.1 19.5 0.47 10.8 1.8 3.3 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 OAJ32209.1 - 3 8.2 20.7 5 7.5 7.7 3.7 2 2 0 2 2 2 0 YtxH-like protein FlaC_arch PF05377.6 OAJ32209.1 - 3.5 7.6 4.9 5.7 6.9 0.1 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 OAJ32209.1 - 3.8 7.8 8.0 7.6 6.9 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) COG2 PF06148.6 OAJ32209.1 - 6.3 6.6 13.7 11 5.8 1.0 3.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TP_methylase PF00590.15 OAJ32210.1 - 9.5e-15 54.8 0.6 3e-14 53.2 0.1 2.0 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Ribosomal_L28 PF00830.14 OAJ32211.1 - 4.6e-22 77.6 0.1 7.4e-22 76.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L28 family Brix PF04427.13 OAJ32212.1 - 1.3e-48 165.1 0.1 1.8e-48 164.7 0.1 1.2 1 0 0 1 1 1 1 Brix domain DUF2517 PF10725.4 OAJ32212.1 - 0.0086 15.7 0.1 0.18 11.5 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2517) DUF4128 PF13554.1 OAJ32212.1 - 0.024 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function STAT1_TAZ2bind PF12162.3 OAJ32213.1 - 0.0037 16.6 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 STAT1 TAZ2 binding domain ubiquitin PF00240.18 OAJ32214.1 - 3.5e-69 228.1 8.2 2.7e-34 116.3 0.7 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 OAJ32214.1 - 5e-40 135.0 7.4 1.3e-19 69.5 0.6 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAJ32214.1 - 4.1e-13 49.4 2.6 4.2e-05 23.7 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAJ32214.1 - 5.7e-11 42.3 0.1 0.00025 20.7 0.0 2.0 2 0 0 2 2 2 2 Telomere stability and silencing Rad60-SLD_2 PF13881.1 OAJ32214.1 - 2.8e-07 30.3 0.4 0.035 13.9 0.0 2.7 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 OAJ32214.1 - 4.7e-07 29.9 0.2 0.031 14.4 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 OAJ32214.1 - 5.2e-05 23.2 0.0 0.51 10.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 OAJ32214.1 - 0.0022 17.7 0.6 2.4 7.9 0.0 2.3 2 0 0 2 2 2 2 FlgD Ig-like domain TUG-UBL1 PF11470.3 OAJ32214.1 - 0.0028 17.5 0.7 2.2 8.2 0.0 2.2 2 0 0 2 2 2 2 GLUT4 regulating protein TUG DUF3221 PF11518.3 OAJ32214.1 - 0.0064 16.1 0.2 3.7 7.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3221) Plexin_cytopl PF08337.7 OAJ32214.1 - 0.0069 14.7 3.0 1.1 7.4 0.3 3.3 3 1 0 3 3 3 1 Plexin cytoplasmic RasGAP domain IGR PF09597.5 OAJ32214.1 - 0.018 14.9 0.0 8.8 6.3 0.0 2.4 2 0 0 2 2 2 0 IGR protein motif Big_3_3 PF13750.1 OAJ32214.1 - 0.02 14.2 0.0 6.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) USP7_C2 PF14533.1 OAJ32214.1 - 0.056 12.8 0.5 8.1 5.8 0.0 2.1 1 1 0 2 2 2 0 Ubiquitin-specific protease C-terminal Tash_PEST PF07708.6 OAJ32214.1 - 0.069 13.0 10.5 1.5 8.8 1.2 2.4 2 0 0 2 2 2 0 Tash protein PEST motif GABP-alpha PF11620.3 OAJ32214.1 - 0.088 12.7 0.8 12 5.9 0.1 2.1 2 0 0 2 2 2 0 GA-binding protein alpha chain DUF3861 PF12977.2 OAJ32214.1 - 0.098 12.7 0.7 14 5.8 0.1 2.4 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2207 PF09972.4 OAJ32214.1 - 0.15 10.5 4.0 3.4 6.1 0.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CTDII PF01556.13 OAJ32214.1 - 0.16 11.8 5.0 2 8.3 0.4 2.5 1 1 1 2 2 2 0 DnaJ C terminal domain FERM_N PF09379.5 OAJ32214.1 - 0.25 11.3 4.5 19 5.4 0.3 3.4 2 2 0 2 2 2 0 FERM N-terminal domain eIF_4EBP PF05456.6 OAJ32215.1 - 3e-10 39.7 1.0 3e-10 39.7 0.7 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) ubiquitin PF00240.18 OAJ32216.1 - 1.3e-102 335.2 16.4 6.6e-34 115.1 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 OAJ32216.1 - 6.7e-59 195.5 15.0 3.3e-19 68.3 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAJ32216.1 - 1.1e-18 67.2 7.1 9.6e-05 22.5 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAJ32216.1 - 2.7e-16 59.6 0.5 0.00062 19.4 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing DUF2407 PF10302.4 OAJ32216.1 - 9e-11 41.8 0.8 0.066 13.4 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 OAJ32216.1 - 9.7e-11 41.5 1.5 0.081 12.8 0.0 3.8 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 OAJ32216.1 - 7e-08 32.4 0.0 1 9.4 0.0 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 OAJ32216.1 - 5.7e-05 22.7 2.5 4.5 7.0 0.0 3.3 3 0 0 3 3 3 3 FlgD Ig-like domain TUG-UBL1 PF11470.3 OAJ32216.1 - 0.00017 21.4 3.3 4.8 7.1 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF3221 PF11518.3 OAJ32216.1 - 0.00021 20.9 0.8 8.5 6.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3221) Methyltrans_RNA PF04452.9 OAJ32216.1 - 0.00038 19.6 0.2 0.83 8.7 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase IGR PF09597.5 OAJ32216.1 - 0.00041 20.1 0.1 16 5.4 0.0 3.3 3 0 0 3 3 3 0 IGR protein motif Big_3_3 PF13750.1 OAJ32216.1 - 0.00059 19.2 0.0 12 5.2 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 OAJ32216.1 - 0.0048 15.2 8.7 2.4 6.3 0.2 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain USP7_C2 PF14533.1 OAJ32216.1 - 0.0076 15.6 2.2 14 5.0 0.0 3.0 1 1 1 3 3 3 0 Ubiquitin-specific protease C-terminal ACT_4 PF13291.1 OAJ32216.1 - 0.023 15.0 0.4 72 3.8 0.0 3.2 3 0 0 3 3 3 0 ACT domain DUF3861 PF12977.2 OAJ32216.1 - 0.027 14.5 3.2 34 4.6 0.0 3.4 1 1 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) Tash_PEST PF07708.6 OAJ32216.1 - 0.036 13.9 19.8 2.5 8.1 1.2 3.4 3 0 0 3 3 3 0 Tash protein PEST motif GABP-alpha PF11620.3 OAJ32216.1 - 0.041 13.8 3.9 28 4.7 0.1 3.1 3 0 0 3 3 3 0 GA-binding protein alpha chain EMG1 PF03587.9 OAJ32216.1 - 0.059 12.6 0.9 16 4.6 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase CTDII PF01556.13 OAJ32216.1 - 0.067 13.0 10.9 4.1 7.3 0.3 3.5 1 1 2 3 3 3 0 DnaJ C terminal domain Sortase PF04203.8 OAJ32216.1 - 0.14 11.7 1.6 23 4.5 0.0 3.0 1 1 2 3 3 3 0 Sortase family FERM_N PF09379.5 OAJ32216.1 - 0.39 10.8 9.5 37 4.4 0.2 4.7 3 3 0 3 3 3 0 FERM N-terminal domain DUF3781 PF12636.2 OAJ32216.1 - 0.55 10.2 3.9 82 3.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) Hist_deacetyl PF00850.14 OAJ32217.1 - 5.3e-81 272.2 0.0 7.6e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ATP-synt_F PF01990.12 OAJ32218.1 - 3.9e-27 94.4 0.1 4.4e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF2413 PF10310.4 OAJ32219.1 - 3.1e-54 184.4 4.7 5.2e-53 180.4 3.3 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) Pardaxin PF07425.6 OAJ32219.1 - 0.057 12.8 1.0 0.18 11.2 0.7 1.8 1 0 0 1 1 1 0 Pardaxin DUF3439 PF11921.3 OAJ32219.1 - 4.1 7.1 10.8 10 5.9 7.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CBS PF00571.23 OAJ32221.1 - 1.4e-34 117.5 8.9 5.7e-09 35.6 0.0 5.2 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 OAJ32221.1 - 2.3e-06 27.1 0.1 2.1e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 PB1 domain Ribosomal_S27e PF01667.12 OAJ32223.1 - 1.7e-29 101.1 2.4 2.1e-29 100.8 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-CSL PF05207.8 OAJ32223.1 - 0.028 13.9 0.5 0.052 13.0 0.3 1.4 1 0 0 1 1 1 0 CSL zinc finger RIX1 PF08167.7 OAJ32223.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis DUF3133 PF11331.3 OAJ32223.1 - 0.14 11.7 4.9 0.5 9.9 2.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) Ribosomal_S27e PF01667.12 OAJ32224.1 - 1.7e-29 101.1 2.4 2.1e-29 100.8 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-CSL PF05207.8 OAJ32224.1 - 0.028 13.9 0.5 0.052 13.0 0.3 1.4 1 0 0 1 1 1 0 CSL zinc finger RIX1 PF08167.7 OAJ32224.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis DUF3133 PF11331.3 OAJ32224.1 - 0.14 11.7 4.9 0.5 9.9 2.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) Ribosomal_L19e PF01280.15 OAJ32225.1 - 6.2e-59 198.0 12.4 6.2e-59 198.0 8.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e S4 PF01479.20 OAJ32225.1 - 0.0029 16.9 0.2 0.01 15.2 0.1 1.9 1 0 0 1 1 1 1 S4 domain Adeno_E4_34 PF04528.8 OAJ32225.1 - 2.4 7.7 5.5 18 4.8 0.1 2.3 2 0 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region AA_permease_2 PF13520.1 OAJ32226.1 - 1e-81 274.6 39.2 1.2e-81 274.4 27.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAJ32226.1 - 3.1e-19 68.6 33.0 7.1e-19 67.4 22.9 1.5 1 1 0 1 1 1 1 Amino acid permease ATP12 PF07542.6 OAJ32227.1 - 2.4e-36 124.3 0.0 4.2e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Zn_clus PF00172.13 OAJ32228.1 - 5.9e-08 32.4 28.1 6e-06 26.0 5.9 3.3 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4051 PF13260.1 OAJ32228.1 - 0.21 10.9 0.1 0.44 9.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Ribonuc_L-PSP PF01042.16 OAJ32229.1 - 3.1e-41 139.9 0.1 3.6e-41 139.7 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Serglycin PF04360.7 OAJ32230.1 - 0.0094 15.6 1.1 0.017 14.8 0.8 1.4 1 0 0 1 1 1 1 Serglycin zf-BED PF02892.10 OAJ32230.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 BED zinc finger Glyco_hydro_88 PF07470.8 OAJ32231.1 - 1.3e-14 54.0 1.0 2.7e-14 52.9 0.5 1.6 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 EF_TS PF00889.14 OAJ32232.1 - 1.6e-14 53.7 0.0 6.8e-13 48.4 0.0 2.9 3 0 0 3 3 3 1 Elongation factor TS Afi1 PF07792.7 OAJ32233.1 - 5e-43 146.5 0.0 7.8e-43 145.9 0.0 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 OAJ32233.1 - 1.9e-34 117.7 0.0 4.5e-34 116.5 0.0 1.6 2 0 0 2 2 2 1 Stabilization of polarity axis Avl9 PF09794.4 OAJ32233.1 - 2.8e-09 35.9 0.0 0.00011 20.8 0.0 3.6 2 2 1 3 3 3 2 Transport protein Avl9 DUF2347 PF09804.4 OAJ32233.1 - 0.03 13.6 0.0 3.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) FUSC_2 PF13515.1 OAJ32234.1 - 2e-15 56.8 16.9 2e-15 56.8 11.7 3.0 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 OAJ32234.1 - 1.7e-13 49.9 0.0 3.7e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Aluminium activated malate transporter DUF2422 PF10337.4 OAJ32234.1 - 7.5e-11 41.4 6.9 7.5e-11 41.4 4.8 4.5 4 1 0 4 4 4 1 Protein of unknown function (DUF2422) FUSC PF04632.7 OAJ32234.1 - 1.2e-08 33.9 21.6 1.2e-08 33.9 15.0 3.5 3 2 0 3 3 3 1 Fusaric acid resistance protein family DUF939 PF06081.6 OAJ32234.1 - 2.8e-07 30.4 8.1 1e-06 28.6 5.6 2.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF939) DUF2421 PF10334.4 OAJ32234.1 - 4.7e-05 23.1 0.8 0.00019 21.1 0.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) MbeB_N PF04837.7 OAJ32234.1 - 0.23 11.6 3.1 0.31 11.1 0.1 2.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Ribonuc_2-5A PF06479.7 OAJ32236.1 - 6.3e-43 145.6 0.0 1.1e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 OAJ32236.1 - 9.4e-42 142.9 0.0 1.5e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ32236.1 - 5.6e-20 71.5 0.0 3.2e-19 69.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 OAJ32236.1 - 0.0023 17.3 0.0 0.025 14.1 0.0 2.5 2 0 0 2 2 2 1 PQQ enzyme repeat Kdo PF06293.9 OAJ32236.1 - 0.0042 16.1 0.0 0.0077 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 OAJ32236.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Nucleoplasmin PF03066.10 OAJ32236.1 - 0.25 10.8 2.7 0.22 11.0 0.2 2.0 2 0 0 2 2 2 0 Nucleoplasmin ArsB PF02040.10 OAJ32238.1 - 1.2e-16 60.7 19.5 2.1e-09 36.8 4.7 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein Nucleoporin_C PF03177.9 OAJ32239.1 - 8.2e-78 262.3 8.2 1.1e-77 261.9 5.7 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 OAJ32239.1 - 3.6e-54 184.1 0.1 5.7e-54 183.4 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like SMC_N PF02463.14 OAJ32240.1 - 3.8e-21 75.3 0.0 7.5e-21 74.3 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAJ32240.1 - 3.1e-14 53.7 12.0 3.1e-14 53.7 8.3 5.4 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 OAJ32240.1 - 4.6e-06 26.8 0.0 3.3e-05 24.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 OAJ32240.1 - 0.00013 21.4 0.3 0.0011 18.4 0.0 2.6 3 1 1 4 4 4 1 P-loop containing region of AAA domain AAA_22 PF13401.1 OAJ32240.1 - 0.079 13.1 3.4 1.3 9.2 0.0 3.7 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.22 OAJ32240.1 - 0.079 13.2 0.0 0.079 13.2 0.0 5.1 3 2 0 3 3 3 0 ABC transporter AAA_13 PF13166.1 OAJ32240.1 - 0.094 11.1 62.4 0.096 11.1 9.5 4.7 3 2 1 4 4 4 0 AAA domain AAA_19 PF13245.1 OAJ32240.1 - 0.1 12.3 0.1 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Surfac_D-trimer PF09006.6 OAJ32240.1 - 8.8 6.1 10.6 5.5 6.8 0.6 4.1 3 1 1 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation Peptidase_M28 PF04389.12 OAJ32241.1 - 5.6e-31 107.6 0.0 9e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 OAJ32241.1 - 0.0011 18.5 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF4449 PF14613.1 OAJ32242.1 - 0.0011 18.9 7.6 0.0025 17.7 0.0 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF4449) DUF1910 PF08928.5 OAJ32242.1 - 0.0022 18.0 0.4 0.48 10.4 0.0 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF1910) Phage_connect_1 PF05135.8 OAJ32242.1 - 0.24 11.6 3.5 1.2 9.3 0.5 3.0 2 1 1 3 3 3 0 Phage gp6-like head-tail connector protein SurE PF01975.12 OAJ32243.1 - 2.8e-39 134.4 0.0 6.6e-39 133.2 0.0 1.6 1 1 0 1 1 1 1 Survival protein SurE Glyco_trans_4_4 PF13579.1 OAJ32243.1 - 0.028 14.5 0.1 0.088 12.9 0.0 2.0 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Clp1 PF06807.9 OAJ32244.1 - 1e-18 67.8 0.0 1.1e-17 64.4 0.0 2.1 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 OAJ32244.1 - 0.0034 17.1 0.0 0.0085 15.7 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 OAJ32244.1 - 0.0057 16.6 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 OAJ32244.1 - 0.021 15.3 0.0 0.042 14.3 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 OAJ32244.1 - 0.031 14.2 0.1 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase WD40 PF00400.27 OAJ32245.1 - 9.1e-12 44.3 3.1 0.14 12.1 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.1 OAJ32245.1 - 0.0048 17.1 1.4 6 7.2 0.0 4.6 5 0 0 5 5 5 1 PQQ-like domain PQQ_2 PF13360.1 OAJ32245.1 - 0.0064 15.9 0.1 0.099 12.0 0.0 2.3 2 0 0 2 2 2 1 PQQ-like domain Med3 PF11593.3 OAJ32245.1 - 0.58 9.3 10.3 0.057 12.6 2.4 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF2970 PF11174.3 OAJ32246.1 - 0.09 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Ecl1 PF12855.2 OAJ32247.1 - 7e-08 31.6 0.0 0.0032 16.7 0.0 2.5 2 0 0 2 2 2 2 Life-span regulatory factor Aa_trans PF01490.13 OAJ32248.1 - 1.2e-45 155.7 32.5 1.4e-45 155.5 22.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sex_peptide PF08138.6 OAJ32248.1 - 0.072 12.9 0.0 14 5.6 0.0 3.7 3 0 0 3 3 3 0 Sex peptide (SP) family DUF4231 PF14015.1 OAJ32248.1 - 0.52 10.3 0.0 0.52 10.3 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Anoctamin PF04547.7 OAJ32248.1 - 3.1 6.3 10.7 0.015 14.0 0.7 2.1 2 1 0 2 2 2 0 Calcium-activated chloride channel Milton PF12448.3 OAJ32249.1 - 3 7.9 12.2 0.59 10.3 5.1 2.3 2 1 0 2 2 2 0 Kinesin associated protein Nop14 PF04147.7 OAJ32249.1 - 3.3 5.5 8.8 4.2 5.1 6.1 1.3 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_16 PF00722.16 OAJ32250.1 - 7e-31 106.9 1.7 1.2e-30 106.1 1.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 OAJ32250.1 - 0.0046 16.9 18.3 0.012 15.5 12.7 1.7 1 0 0 1 1 1 1 Chitin recognition protein MutL_C PF08676.6 OAJ32251.1 - 5.9e-09 35.6 0.0 2.5e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 OAJ32251.1 - 0.0015 18.2 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAJ32251.1 - 0.0039 16.8 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GMC_oxred_N PF00732.14 OAJ32252.1 - 3.8e-51 174.0 0.0 6.3e-51 173.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ32252.1 - 1.9e-36 125.4 0.0 4.2e-36 124.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAJ32252.1 - 0.00013 21.0 0.2 0.0012 17.8 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ32252.1 - 0.0014 18.6 0.2 0.006 16.5 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAJ32252.1 - 0.0022 16.8 1.0 0.1 11.4 0.8 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 OAJ32252.1 - 0.0025 16.8 0.7 0.0045 15.9 0.5 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 OAJ32252.1 - 0.0037 17.1 1.2 0.018 14.9 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase SGS PF05002.10 OAJ32253.1 - 9.6e-26 89.3 1.7 2e-25 88.3 1.1 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.11 OAJ32253.1 - 1.9e-08 34.7 0.0 5.4e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 CS domain Methyltransf_28 PF02636.12 OAJ32254.1 - 3.1e-64 216.8 0.0 3.8e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CRAL_TRIO PF00650.15 OAJ32256.1 - 3.7e-34 117.5 0.0 5.7e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ32256.1 - 1.1e-08 35.0 0.4 3.1e-08 33.6 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain ThiS PF02597.15 OAJ32256.1 - 5.3e-08 33.1 0.1 4.7e-07 30.1 0.1 2.5 2 0 0 2 2 2 1 ThiS family Fe_bilin_red PF05996.7 OAJ32256.1 - 1.5 8.2 6.0 2.7 7.4 4.1 1.3 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase Uds1 PF15456.1 OAJ32257.1 - 2.6e-14 53.3 3.8 1.7e-11 44.2 0.2 14.6 6 1 7 14 14 14 2 Up-regulated During Septation Pyr_redox_3 PF13738.1 OAJ32258.1 - 4.3e-13 49.7 0.0 6.7e-12 45.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ32258.1 - 4.1e-09 36.3 0.2 0.0003 20.5 0.0 3.5 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAJ32258.1 - 5.7e-09 35.8 0.0 2.2e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 OAJ32258.1 - 2.9e-06 25.7 0.0 0.13 10.4 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 OAJ32258.1 - 2.9e-05 24.0 0.0 0.091 12.6 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ32258.1 - 4.7e-05 22.4 0.0 0.0092 14.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 OAJ32258.1 - 9.2e-05 21.4 0.4 0.022 13.7 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 OAJ32258.1 - 0.012 15.6 0.0 6.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 OAJ32258.1 - 0.017 14.2 0.0 0.055 12.5 0.0 1.8 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 OAJ32258.1 - 0.033 12.6 0.0 1.5 7.1 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 OAJ32258.1 - 0.037 12.9 0.1 2.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 OAJ32258.1 - 0.049 12.5 0.0 5.6 5.7 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 OAJ32258.1 - 0.19 12.1 0.1 0.42 11.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase E3_binding PF02817.12 OAJ32259.1 - 6.2e-09 35.3 0.1 1.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 e3 binding domain Response_reg PF00072.19 OAJ32260.1 - 1.4e-06 28.2 0.0 4.3e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain DUF1777 PF08648.7 OAJ32262.1 - 2.3e-19 69.8 31.4 2.3e-19 69.8 21.7 3.7 1 1 2 3 3 3 2 Protein of unknown function (DUF1777) Pkinase PF00069.20 OAJ32263.1 - 2.2e-60 203.9 0.0 2.8e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ32263.1 - 8.8e-34 116.7 0.0 1.2e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ32263.1 - 1.3e-06 27.6 0.0 2.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ32263.1 - 0.031 14.0 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ32263.1 - 0.077 11.8 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 OAJ32263.1 - 0.092 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 OAJ32263.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SET PF00856.23 OAJ32264.1 - 1.7e-09 38.1 0.1 1.7e-09 38.1 0.0 3.4 4 2 0 4 4 4 1 SET domain Cytochrom_NNT PF03264.9 OAJ32264.1 - 0.067 12.6 3.3 0.13 11.6 2.3 1.4 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region TPMT PF05724.6 OAJ32265.1 - 1.4e-33 116.2 0.0 1.7e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 OAJ32265.1 - 1.9e-09 37.3 0.0 2.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ32265.1 - 7.4e-09 36.1 0.0 1.3e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ32265.1 - 6.8e-08 32.8 0.0 1e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ32265.1 - 2.8e-06 27.7 0.0 6.6e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ32265.1 - 4e-06 26.8 0.0 8.9e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ32265.1 - 1.1e-05 25.6 0.0 1.6e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ32265.1 - 5.4e-05 22.9 0.0 7.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 OAJ32265.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB DUF4345 PF14248.1 OAJ32266.1 - 0.1 12.0 0.7 0.64 9.4 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) DUF1708 PF08101.6 OAJ32267.1 - 1.7e-23 83.1 0.1 4e-17 62.1 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF1708) RhoGAP PF00620.22 OAJ32267.1 - 3.9e-05 23.2 0.0 0.00036 20.1 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain Peptidase_C65 PF10275.4 OAJ32272.1 - 1e-59 201.8 0.0 1.3e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 OAJ32272.1 - 1.6e-05 25.5 0.0 8.9e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 OTU-like cysteine protease Zn_clus PF00172.13 OAJ32273.1 - 0.00027 20.7 12.0 0.00044 20.0 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 OAJ32273.1 - 0.00052 18.9 20.7 0.00052 18.9 14.3 4.9 3 1 2 5 5 5 1 BAF1 / ABF1 chromatin reorganising factor Macoilin PF09726.4 OAJ32273.1 - 0.98 7.6 17.8 2.2 6.4 0.5 2.3 2 0 0 2 2 2 0 Transmembrane protein His_Phos_1 PF00300.17 OAJ32274.1 - 1.1e-16 61.3 0.0 1.4e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 OAJ32274.1 - 0.015 14.6 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) zf-RING_4 PF14570.1 OAJ32275.1 - 6.1e-21 73.7 11.5 9.8e-21 73.0 8.0 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 OAJ32275.1 - 1.2e-05 24.9 8.2 2e-05 24.1 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ32275.1 - 0.017 15.1 12.1 0.028 14.4 8.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 OAJ32275.1 - 0.022 14.6 0.0 0.12 12.2 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.1 OAJ32275.1 - 0.026 14.2 3.4 0.062 13.0 2.4 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger RRM_1 PF00076.17 OAJ32275.1 - 0.053 13.1 0.0 0.26 10.9 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 OAJ32275.1 - 1.2 8.8 7.9 1 9.0 4.3 1.7 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Vps55 PF04133.9 OAJ32276.1 - 2.2e-44 150.0 4.7 2.5e-44 149.8 3.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 FtsX PF02687.16 OAJ32276.1 - 5 6.9 10.4 1.5 8.6 4.3 2.1 1 1 1 2 2 2 0 FtsX-like permease family Phosducin PF02114.11 OAJ32277.1 - 0.033 12.9 2.1 5.1 5.7 1.1 2.3 2 0 0 2 2 2 0 Phosducin CAP-ZIP_m PF15255.1 OAJ32277.1 - 0.19 11.6 7.0 0.37 10.7 0.4 2.5 2 0 0 2 2 2 0 WASH complex subunit CAP-Z interacting, central region GOLD_2 PF13897.1 OAJ32277.1 - 0.71 10.1 4.9 0.14 12.4 0.4 1.9 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Pap_E4 PF02711.9 OAJ32277.1 - 0.74 10.6 7.4 0.26 12.1 2.1 2.4 2 0 0 2 2 2 0 E4 protein Sigma70_ner PF04546.8 OAJ32277.1 - 1.2 8.6 14.1 0.61 9.6 5.1 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.7 OAJ32277.1 - 1.2 8.7 17.0 0.14 11.8 7.6 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 OAJ32277.1 - 8 5.9 14.9 7.6 6.0 7.5 2.3 2 0 0 2 2 2 0 Nucleoplasmin Response_reg PF00072.19 OAJ32278.1 - 6.7e-24 84.0 0.0 1.4e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 OAJ32278.1 - 6.6e-20 70.8 0.0 1.1e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GxGYxYP PF14323.1 OAJ32278.1 - 0.14 10.8 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function Nucleoplasmin PF03066.10 OAJ32280.1 - 1.7 8.1 5.7 0.57 9.6 0.2 2.1 2 0 0 2 2 2 0 Nucleoplasmin DUF2201_N PF13203.1 OAJ32281.1 - 0.2 10.7 8.0 0.25 10.4 5.6 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4407 PF14362.1 OAJ32281.1 - 0.47 9.3 9.2 0.67 8.8 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.11 OAJ32281.1 - 3.1 7.6 4.4 3.6 7.4 3.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ThiF PF00899.16 OAJ32282.1 - 8.2e-39 132.5 0.1 1.2e-38 132.0 0.1 1.2 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 OAJ32282.1 - 3e-22 77.9 0.0 5e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 OAJ32282.1 - 7.7e-08 32.6 0.0 3.2e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 Rhodanese-like domain NAD_binding_7 PF13241.1 OAJ32282.1 - 4.8e-06 26.7 0.0 9.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 OAJ32282.1 - 1.8e-05 24.8 0.1 4.9e-05 23.4 0.0 1.7 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 OAJ32282.1 - 0.06 12.7 0.1 0.093 12.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 OAJ32282.1 - 0.091 11.6 0.3 0.15 10.9 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GCV_H PF01597.14 OAJ32282.1 - 0.093 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein AAA_5 PF07728.9 OAJ32283.1 - 5.3e-115 379.3 0.1 1.5e-19 70.0 0.0 10.3 9 1 0 10 10 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 OAJ32283.1 - 7e-27 94.2 0.1 0.0039 17.3 0.0 7.9 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 OAJ32283.1 - 1.9e-24 85.7 0.0 7.9e-08 31.9 0.0 7.6 8 0 0 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ32283.1 - 5e-24 84.9 1.3 0.0069 16.5 0.0 8.3 7 0 0 7 7 6 6 AAA domain ABC_tran PF00005.22 OAJ32283.1 - 1.7e-17 64.0 0.3 0.0026 18.0 0.0 6.9 6 1 0 6 6 6 4 ABC transporter AAA_33 PF13671.1 OAJ32283.1 - 5.8e-17 61.9 2.3 0.025 14.4 0.1 8.1 6 1 0 6 6 6 4 AAA domain AAA_19 PF13245.1 OAJ32283.1 - 1.6e-16 59.7 10.1 0.054 13.2 0.0 7.2 6 0 0 6 6 6 5 Part of AAA domain Sigma54_activat PF00158.21 OAJ32283.1 - 1.1e-15 57.4 0.1 0.005 16.3 0.0 5.8 6 0 0 6 6 5 3 Sigma-54 interaction domain AAA_14 PF13173.1 OAJ32283.1 - 2.1e-15 56.7 0.0 0.0037 17.1 0.0 6.7 8 0 0 8 8 5 3 AAA domain AAA_17 PF13207.1 OAJ32283.1 - 6.2e-15 56.0 5.6 0.27 12.0 0.0 7.5 7 0 0 7 7 6 4 AAA domain AAA_18 PF13238.1 OAJ32283.1 - 1.6e-14 54.3 0.4 0.15 12.3 0.0 7.0 6 0 0 6 6 6 2 AAA domain AAA_16 PF13191.1 OAJ32283.1 - 2.6e-14 53.6 60.2 4.3e-05 23.5 0.6 12.5 11 3 0 11 11 7 5 AAA ATPase domain Sigma54_activ_2 PF14532.1 OAJ32283.1 - 5.1e-14 52.4 0.8 0.0098 15.9 0.1 6.8 6 0 0 6 6 6 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 OAJ32283.1 - 6.1e-14 51.5 1.4 0.02 14.0 0.0 7.1 6 1 0 6 6 6 2 Zeta toxin AAA_29 PF13555.1 OAJ32283.1 - 2.4e-12 46.1 1.4 0.071 12.6 0.0 6.2 6 0 0 6 6 6 3 P-loop containing region of AAA domain NACHT PF05729.7 OAJ32283.1 - 5.9e-12 45.5 2.5 0.0027 17.4 0.0 6.1 5 0 0 5 5 5 2 NACHT domain AAA_25 PF13481.1 OAJ32283.1 - 6.7e-12 45.2 10.5 0.087 12.2 0.0 7.1 6 0 0 6 6 6 3 AAA domain UPF0079 PF02367.12 OAJ32283.1 - 2.1e-11 43.5 1.5 0.044 13.4 0.0 6.1 6 0 0 6 6 6 2 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 OAJ32283.1 - 3e-11 43.8 0.3 1.2 9.6 0.0 7.1 7 0 0 7 7 6 2 Miro-like protein AAA_28 PF13521.1 OAJ32283.1 - 3.5e-11 43.3 6.1 0.88 9.5 0.0 7.2 6 0 0 6 6 6 2 AAA domain T2SE PF00437.15 OAJ32283.1 - 7.7e-11 41.4 6.4 0.14 10.9 0.0 6.6 6 0 0 6 6 6 2 Type II/IV secretion system protein DUF258 PF03193.11 OAJ32283.1 - 1.7e-09 37.0 1.2 0.061 12.5 0.0 5.7 6 0 0 6 6 5 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 OAJ32283.1 - 2e-09 37.6 0.6 1.1 9.4 0.0 6.7 6 0 0 6 6 6 1 RNA helicase MobB PF03205.9 OAJ32283.1 - 2.7e-09 36.8 2.0 0.23 11.1 0.0 6.4 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 OAJ32283.1 - 9.5e-09 34.7 6.0 0.1 11.7 0.1 7.8 8 0 0 8 8 7 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 OAJ32283.1 - 2.1e-08 33.3 1.5 0.31 9.9 0.0 6.0 7 0 0 7 7 6 1 Protein of unknown function (DUF815) PduV-EutP PF10662.4 OAJ32283.1 - 5.6e-07 29.1 2.2 0.31 10.5 0.0 5.5 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 OAJ32283.1 - 6.9e-06 25.7 1.3 5.6 6.4 0.0 5.8 6 0 0 6 6 6 0 AAA domain Arch_ATPase PF01637.13 OAJ32283.1 - 1.6e-05 24.7 0.0 3.4 7.3 0.0 5.3 6 0 0 6 6 5 0 Archaeal ATPase SRP54 PF00448.17 OAJ32283.1 - 8.9e-05 22.0 5.2 1.1 8.7 0.0 5.4 5 0 0 5 5 4 1 SRP54-type protein, GTPase domain cobW PF02492.14 OAJ32283.1 - 0.0001 21.7 7.3 2.2 7.6 0.0 5.4 6 0 0 6 6 5 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.2 OAJ32283.1 - 0.00011 21.4 0.0 0.2 10.7 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 MMR_HSR1 PF01926.18 OAJ32283.1 - 0.00015 21.6 0.1 13 5.7 0.0 5.8 6 0 0 6 6 5 0 50S ribosome-binding GTPase ResIII PF04851.10 OAJ32283.1 - 0.00017 21.5 0.8 2.9 7.6 0.0 4.7 5 0 0 5 5 3 1 Type III restriction enzyme, res subunit KaiC PF06745.8 OAJ32283.1 - 0.00022 20.4 0.8 5.7 5.9 0.0 4.9 5 0 0 5 5 5 0 KaiC ArgK PF03308.11 OAJ32283.1 - 0.00032 19.5 1.5 0.84 8.3 0.0 3.4 3 0 0 3 3 3 2 ArgK protein PhoH PF02562.11 OAJ32283.1 - 0.001 18.3 2.8 4.2 6.5 0.1 4.2 4 0 0 4 4 4 0 PhoH-like protein TIP49 PF06068.8 OAJ32283.1 - 0.0019 16.9 3.6 2.7 6.6 0.0 4.5 5 0 0 5 5 5 1 TIP49 C-terminus AAA_23 PF13476.1 OAJ32283.1 - 0.003 17.9 0.0 0.003 17.9 0.0 7.3 7 1 0 7 7 6 2 AAA domain NTPase_1 PF03266.10 OAJ32283.1 - 0.0037 16.9 3.8 4 7.1 0.0 5.2 5 0 0 5 5 5 0 NTPase ATP_bind_1 PF03029.12 OAJ32283.1 - 0.0075 15.8 2.3 9.6 5.6 0.0 4.5 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_6 PF12774.2 OAJ32283.1 - 0.023 14.2 0.0 35 3.8 0.0 4.3 5 0 0 5 5 4 0 Hydrolytic ATP binding site of dynein motor region D1 AAA_21 PF13304.1 OAJ32283.1 - 0.024 14.5 0.0 7.3 6.4 0.0 4.1 4 0 0 4 4 4 0 AAA domain Rad17 PF03215.10 OAJ32283.1 - 0.034 12.8 0.2 4.3 5.8 0.0 3.5 4 0 0 4 4 4 0 Rad17 cell cycle checkpoint protein Bac_DnaA PF00308.13 OAJ32283.1 - 0.048 13.3 0.0 6.5 6.3 0.0 3.2 3 0 0 3 3 2 0 Bacterial dnaA protein Herpes_Helicase PF02689.9 OAJ32283.1 - 0.56 7.8 0.0 20 2.7 0.0 2.3 2 0 0 2 2 2 0 Helicase Gtr1_RagA PF04670.7 OAJ32283.1 - 1.1 8.3 2.2 63 2.5 0.0 3.7 5 0 0 5 5 4 0 Gtr1/RagA G protein conserved region PEPCK_ATP PF01293.15 OAJ32283.1 - 1.8 6.9 0.6 3.2 6.1 0.1 1.5 2 0 0 2 2 1 0 Phosphoenolpyruvate carboxykinase Ferritin_2 PF13668.1 OAJ32284.1 - 1.4e-10 41.2 0.0 2.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Pyr_redox_2 PF07992.9 OAJ32285.1 - 1e-39 136.4 0.2 1.9e-39 135.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 OAJ32285.1 - 2.2e-33 114.5 1.0 5.1e-33 113.3 0.7 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 OAJ32285.1 - 1.6e-19 70.0 4.0 7.8e-18 64.6 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase PAP2 PF01569.16 OAJ32285.1 - 1.5e-16 60.2 2.3 4.6e-16 58.6 1.6 1.9 1 0 0 1 1 1 1 PAP2 superfamily Pyr_redox_3 PF13738.1 OAJ32285.1 - 4.1e-15 56.3 0.0 3.1e-09 37.2 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ32285.1 - 4e-06 25.5 0.6 0.029 12.8 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.2 OAJ32285.1 - 7.1e-05 22.0 0.9 0.00024 20.3 0.6 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 OAJ32285.1 - 0.00052 19.0 0.0 0.0015 17.5 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 OAJ32285.1 - 0.019 14.0 0.2 0.04 12.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 OAJ32285.1 - 0.028 13.3 2.6 1.6 7.5 0.4 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ32285.1 - 0.036 14.1 2.3 0.12 12.3 1.6 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 OAJ32285.1 - 0.07 12.7 3.3 0.13 11.8 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 OAJ32285.1 - 0.11 11.2 2.7 0.48 9.1 1.5 2.2 2 0 0 2 2 2 0 FAD binding domain DUF883 PF05957.8 OAJ32286.1 - 0.0086 16.4 6.9 0.015 15.6 4.1 1.9 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Late_protein_L2 PF00513.13 OAJ32286.1 - 0.011 14.5 1.1 0.014 14.2 0.8 1.1 1 0 0 1 1 1 0 Late Protein L2 Coiled-coil_56 PF09813.4 OAJ32286.1 - 0.014 15.3 0.1 0.03 14.2 0.0 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Aminotran_5 PF00266.14 OAJ32286.1 - 0.035 12.8 0.7 0.048 12.4 0.5 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DUF3384 PF11864.3 OAJ32286.1 - 0.053 11.9 1.9 0.065 11.6 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) Prominin PF05478.6 OAJ32286.1 - 0.087 10.3 1.2 0.11 10.0 0.8 1.0 1 0 0 1 1 1 0 Prominin RFX5_DNA_bdg PF14621.1 OAJ32286.1 - 0.23 11.0 3.8 0.31 10.6 2.6 1.2 1 0 0 1 1 1 0 RFX5 DNA-binding domain ATP-synt_B PF00430.13 OAJ32286.1 - 0.31 10.8 4.7 3.8 7.3 0.3 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Tape_meas_lam_C PF09718.5 OAJ32286.1 - 0.6 10.0 7.0 8.4 6.3 4.7 2.3 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) FliE PF02049.13 OAJ32286.1 - 1.7 8.7 6.1 3.6 7.6 4.2 1.6 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE dCMP_cyt_deam_1 PF00383.17 OAJ32287.1 - 2.4e-11 43.1 0.1 5e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 OAJ32287.1 - 1.1e-06 28.4 0.1 1.5e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Ras PF00071.17 OAJ32288.1 - 2.1e-34 118.2 0.3 2.6e-34 117.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ32288.1 - 2.9e-22 79.3 0.1 1.5e-21 77.1 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 OAJ32288.1 - 6.5e-08 32.0 0.3 8.2e-08 31.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 OAJ32288.1 - 7.9e-08 31.7 0.0 9.8e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ32288.1 - 0.00024 20.6 0.1 0.0022 17.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 OAJ32288.1 - 0.0027 16.4 7.4 0.035 12.8 0.0 2.8 1 1 2 3 3 3 2 G-protein alpha subunit MMR_HSR1 PF01926.18 OAJ32288.1 - 0.0032 17.4 0.0 0.0048 16.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 OAJ32288.1 - 0.062 12.5 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pex14_N PF04695.8 OAJ32288.1 - 0.1 12.6 2.2 0.18 11.8 1.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PHP_C PF13263.1 OAJ32288.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 PHP-associated Utp21 PF04192.7 OAJ32289.1 - 2.6e-51 174.0 0.0 4.7e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 OAJ32289.1 - 1.1e-09 37.8 7.9 0.072 13.0 0.2 7.0 8 0 0 8 8 8 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 OAJ32289.1 - 0.0086 15.8 0.0 0.21 11.3 0.0 3.2 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Apc4_WD40 PF12894.2 OAJ32289.1 - 0.09 12.3 0.0 6 6.4 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PBP1_TM PF14812.1 OAJ32289.1 - 0.094 13.0 2.0 0.26 11.6 1.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 OAJ32289.1 - 3.6 7.0 7.1 0.69 9.4 1.4 2.1 2 0 0 2 2 2 0 Nucleoplasmin SR-25 PF10500.4 OAJ32289.1 - 8.6 5.7 19.4 0.15 11.5 8.3 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein BolA PF01722.13 OAJ32290.1 - 4.5e-17 61.7 0.0 7.1e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein AMP-binding PF00501.23 OAJ32291.1 - 6e-82 275.2 0.0 8e-82 274.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ32291.1 - 0.018 15.9 0.0 0.13 13.2 0.0 2.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain DUF2636 PF11120.3 OAJ32291.1 - 0.11 11.9 0.4 0.26 10.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) RRM_1 PF00076.17 OAJ32292.1 - 5.3e-13 48.4 0.0 8.1e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ32292.1 - 3e-12 46.3 0.0 4.6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ32292.1 - 0.017 14.9 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAF4 PF05236.9 OAJ32292.1 - 4.4 6.5 9.5 14 4.8 5.9 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family RNA_pol_Rpb1_5 PF04998.12 OAJ32293.1 - 2.7e-89 299.0 0.0 6.5e-89 297.8 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 OAJ32293.1 - 8.7e-60 201.4 0.0 1.6e-59 200.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 OAJ32293.1 - 3.3e-34 117.9 0.0 6.9e-34 116.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 OAJ32293.1 - 1.1e-28 100.4 1.7 2.3e-23 83.0 0.0 4.1 5 0 0 5 5 5 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 OAJ32293.1 - 7.5e-22 77.1 0.0 2.6e-21 75.3 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 CDC45 PF02724.9 OAJ32293.1 - 2.2 6.2 26.9 0.72 7.8 12.1 2.3 2 0 0 2 2 2 0 CDC45-like protein C2 PF00168.25 OAJ32294.1 - 1.2e-56 188.5 1.0 6.6e-21 73.9 0.0 4.4 4 0 0 4 4 4 4 C2 domain DUF2404 PF10296.4 OAJ32294.1 - 0.0063 16.6 0.0 0.049 13.7 0.0 2.4 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) W2 PF02020.13 OAJ32295.1 - 1.4e-09 37.7 0.0 1.4e-09 37.7 0.0 4.5 4 1 0 4 4 4 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 OAJ32295.1 - 4.1e-08 32.3 1.2 0.0001 21.6 0.1 3.6 1 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 OAJ32295.1 - 0.00012 21.4 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 OAJ32295.1 - 0.0004 19.8 3.2 0.0036 16.8 2.3 2.4 1 1 1 2 2 2 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 OAJ32295.1 - 0.0045 15.6 0.3 0.0076 14.8 0.2 1.3 1 0 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.2 OAJ32295.1 - 0.019 15.0 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain Autophagy_N PF03986.8 OAJ32296.1 - 1.3e-44 151.5 0.0 2.4e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 OAJ32296.1 - 2.3e-28 98.1 0.1 4.7e-28 97.1 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 OAJ32296.1 - 8.9e-12 43.8 0.3 1.5e-11 43.1 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Mob1_phocein PF03637.12 OAJ32298.1 - 1e-21 77.4 0.0 1.5e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family Vfa1 PF08432.5 OAJ32298.1 - 0.03 14.3 0.2 0.046 13.7 0.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 adh_short PF00106.20 OAJ32299.1 - 2.2e-29 102.4 0.0 2.8e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ32299.1 - 3.3e-21 76.1 0.0 3.9e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ32299.1 - 5.1e-13 49.0 0.0 7.5e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAJ32299.1 - 0.024 14.3 0.2 0.055 13.2 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Requiem_N PF14051.1 OAJ32300.1 - 0.028 14.3 0.1 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. SH3_9 PF14604.1 OAJ32301.1 - 3.6e-14 52.0 1.6 6.9e-14 51.1 0.2 2.0 2 0 0 2 2 2 1 Variant SH3 domain Cofilin_ADF PF00241.15 OAJ32301.1 - 5.8e-14 52.0 0.0 9.8e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.23 OAJ32301.1 - 5.4e-12 44.8 1.1 1.1e-11 43.9 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 OAJ32301.1 - 7.6e-07 28.5 0.1 1.1e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Mgm101p PF06420.7 OAJ32302.1 - 1.9e-85 284.4 0.0 2.3e-85 284.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 DUF2235 PF09994.4 OAJ32303.1 - 1.2e-66 224.9 0.0 1.7e-66 224.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Mso1_C PF14477.1 OAJ32303.1 - 0.077 13.3 0.3 0.26 11.6 0.2 1.9 1 0 0 1 1 1 0 Membrane-polarising domain of Mso1 Abhydrolase_5 PF12695.2 OAJ32303.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2235 PF09994.4 OAJ32304.1 - 1.7e-65 221.1 0.0 2.5e-65 220.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 OAJ32304.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2235 PF09994.4 OAJ32305.1 - 2.4e-65 220.6 0.0 3.3e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Gln-synt_C PF00120.19 OAJ32306.1 - 4e-59 199.8 0.0 4.8e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 OAJ32306.1 - 5.8e-19 67.4 0.0 1.1e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF2235 PF09994.4 OAJ32307.1 - 1.4e-53 182.0 1.0 8.3e-31 107.3 0.1 2.2 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 OAJ32307.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2828 PF11443.3 OAJ32308.1 - 3.6e-144 480.8 0.0 4.2e-144 480.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) adh_short PF00106.20 OAJ32309.1 - 2.1e-22 79.8 0.5 5.9e-22 78.3 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ32309.1 - 2e-17 63.7 0.1 2.5e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ32309.1 - 3e-07 30.2 0.1 6.7e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 OAJ32309.1 - 0.32 10.8 4.0 6.4 6.6 0.2 2.9 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ras PF00071.17 OAJ32310.1 - 6e-58 194.7 0.0 6.9e-58 194.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ32310.1 - 1.6e-16 60.8 0.0 2.3e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ32310.1 - 6e-07 28.8 0.0 1.1e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ32310.1 - 0.00041 19.8 0.0 0.0019 17.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 OAJ32310.1 - 0.0029 16.8 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 OAJ32310.1 - 0.14 11.6 0.0 12 5.3 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Asp PF00026.18 OAJ32311.1 - 1.7e-27 96.5 0.0 5.8e-27 94.7 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ32311.1 - 0.0024 17.8 0.5 0.0053 16.7 0.1 1.7 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 OAJ32311.1 - 0.04 13.7 0.1 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAJ32311.1 - 0.05 14.1 0.0 2.8 8.5 0.0 3.0 2 1 0 2 2 2 0 Aspartyl protease DNA_pol_B PF00136.16 OAJ32312.1 - 1.5e-89 300.9 0.0 2.1e-89 300.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 OAJ32312.1 - 3.9e-22 78.5 0.0 3.3e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 OAJ32312.1 - 5.4e-11 42.3 6.7 1e-10 41.4 4.6 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta HEAT PF02985.17 OAJ32313.1 - 9.1e-37 121.8 24.2 0.0024 17.7 0.1 13.6 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.1 OAJ32313.1 - 5.9e-32 109.8 5.8 1.8e-08 34.5 0.0 6.7 2 2 3 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 OAJ32313.1 - 5.3e-10 39.5 0.8 0.081 13.3 0.1 6.7 4 2 6 10 10 10 4 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 OAJ32313.1 - 5.8e-09 36.1 23.9 0.31 11.6 0.0 8.8 8 2 2 10 10 10 5 HEAT-like repeat CLASP_N PF12348.3 OAJ32313.1 - 0.00041 19.7 2.3 0.026 13.9 0.1 4.3 1 1 2 4 4 4 1 CLASP N terminal Adaptin_N PF01602.15 OAJ32313.1 - 0.0019 16.6 7.8 0.055 11.7 0.2 4.2 4 1 1 5 5 5 1 Adaptin N terminal region DUF3554 PF12074.3 OAJ32313.1 - 0.015 14.7 0.1 14 4.9 0.0 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF3554) Arm PF00514.18 OAJ32313.1 - 0.12 12.2 5.3 7 6.6 0.0 5.5 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat DUF2404 PF10296.4 OAJ32314.1 - 1.4e-07 31.5 0.0 2.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF515 PF04415.7 OAJ32315.1 - 0.41 8.8 12.6 0.49 8.5 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DNA_pol_viral_N PF00242.12 OAJ32315.1 - 7.2 5.5 6.6 8.1 5.3 4.6 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain zf-C2H2_4 PF13894.1 OAJ32316.1 - 0.086 13.2 8.7 1.6 9.2 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C4H2 PF10146.4 OAJ32316.1 - 0.15 12.0 2.7 0.39 10.6 1.9 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein Vps39_1 PF10366.4 OAJ32317.1 - 3e-28 97.9 1.0 6.2e-28 96.9 0.2 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 OAJ32317.1 - 6.8e-20 71.2 0.2 2.1e-19 69.6 0.1 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 OAJ32317.1 - 4.2e-15 55.9 0.0 8.1e-06 25.4 0.0 3.3 3 0 0 3 3 3 3 CNH domain Clathrin PF00637.15 OAJ32317.1 - 3.6e-09 36.3 3.5 1.3e-05 24.8 0.1 2.9 3 0 0 3 3 3 2 Region in Clathrin and VPS Apc3 PF12895.2 OAJ32317.1 - 0.022 14.8 0.7 0.18 11.9 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 OAJ32317.1 - 0.26 11.3 0.3 23 5.2 0.1 3.3 3 0 0 3 3 3 0 PPR repeat TPR_1 PF00515.23 OAJ32317.1 - 0.36 10.5 4.2 1.8 8.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Hamartin PF04388.7 OAJ32318.1 - 0.49 9.0 6.6 0.68 8.5 4.5 1.1 1 0 0 1 1 1 0 Hamartin protein MFS_1 PF07690.11 OAJ32319.1 - 5.6e-28 97.6 32.9 7.8e-28 97.1 22.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Aldedh PF00171.17 OAJ32320.1 - 3e-129 431.3 0.0 3.6e-129 431.1 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family S-methyl_trans PF02574.11 OAJ32321.1 - 8.5e-35 120.5 0.0 1.7e-33 116.2 0.0 2.5 1 1 0 1 1 1 1 Homocysteine S-methyltransferase DUF4107 PF13389.1 OAJ32321.1 - 0.032 13.9 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) DnaJ PF00226.26 OAJ32322.1 - 1.4e-20 72.7 0.5 2.5e-20 71.9 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Gly-zipper_OmpA PF13436.1 OAJ32322.1 - 0.045 13.4 0.4 0.094 12.3 0.3 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 OAJ32322.1 - 2.1 8.5 9.8 0.59 10.3 4.3 1.8 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.1 OAJ32322.1 - 5.8 6.5 9.8 41 3.7 6.8 2.2 1 1 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 OAJ32322.1 - 7.2 6.3 9.5 5.1 6.8 2.4 2.5 1 1 2 3 3 3 0 Glycine zipper 2TM domain SUR7 PF06687.7 OAJ32323.1 - 8.7e-07 28.7 4.4 1.9e-06 27.6 3.1 1.6 1 1 0 1 1 1 1 SUR7/PalI family Cytochrom_B_N PF00033.14 OAJ32323.1 - 0.014 14.7 0.6 0.014 14.7 0.4 2.2 2 1 1 3 3 3 0 Cytochrome b(N-terminal)/b6/petB HCMV_UL139 PF12507.3 OAJ32323.1 - 0.099 12.8 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein FixQ PF05545.6 OAJ32323.1 - 0.1 12.2 0.4 0.1 12.2 0.2 2.8 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ PSK PF06404.7 OAJ32324.1 - 0.016 15.9 0.9 0.06 14.1 0.4 1.9 1 1 1 2 2 2 0 Phytosulfokine precursor protein (PSK) Uso1_p115_head PF04869.9 OAJ32325.1 - 6.3e-32 110.5 0.0 3.7e-30 104.7 0.0 3.4 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region WEMBL PF05701.6 OAJ32325.1 - 0.0019 16.7 39.2 0.0019 16.7 27.2 2.1 2 0 0 2 2 2 1 Weak chloroplast movement under blue light Cep57_MT_bd PF06657.8 OAJ32325.1 - 7.9 6.5 23.3 0.22 11.4 0.4 4.2 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 RVT_1 PF00078.22 OAJ32326.1 - 1.4e-11 44.1 0.0 2.4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HEAT_2 PF13646.1 OAJ32327.1 - 2.3e-06 27.7 20.6 0.067 13.4 0.0 8.3 7 2 1 8 8 8 3 HEAT repeats HEAT_EZ PF13513.1 OAJ32327.1 - 0.00048 20.5 20.5 0.7 10.4 0.2 8.0 6 1 1 7 7 7 2 HEAT-like repeat HEAT PF02985.17 OAJ32327.1 - 0.0014 18.5 24.5 0.13 12.4 0.1 9.4 11 0 0 11 11 11 2 HEAT repeat Arm PF00514.18 OAJ32327.1 - 0.0041 16.8 2.5 0.027 14.2 0.1 3.8 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat RhoGEF PF00621.15 OAJ32328.1 - 7.6e-17 61.7 0.0 1.4e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DUF3381 PF11861.3 OAJ32329.1 - 0.022 14.2 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) YqcI_YcgG PF08892.6 OAJ32330.1 - 0.025 14.1 0.0 0.03 13.8 0.0 1.1 1 0 0 1 1 1 0 YqcI/YcgG family PUF PF00806.14 OAJ32332.1 - 5.3e-59 192.5 16.5 5.5e-08 31.8 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 OAJ32332.1 - 0.0082 16.4 0.1 0.87 9.8 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function DUF260 CoaE PF01121.15 OAJ32333.1 - 3.6e-58 195.9 0.0 5.8e-58 195.2 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 OAJ32333.1 - 5.8e-06 27.1 0.0 1.2e-05 26.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 OAJ32333.1 - 0.0055 16.5 0.0 0.024 14.5 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase AAA_18 PF13238.1 OAJ32333.1 - 0.0057 16.9 0.1 0.021 15.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ32333.1 - 0.0071 16.2 0.7 0.032 14.0 0.0 2.4 4 0 0 4 4 4 1 AAA domain AIF-MLS PF14962.1 OAJ32337.1 - 0.2 11.2 2.2 0.34 10.5 1.5 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Sybindin PF04099.7 OAJ32338.1 - 1.9e-07 30.9 0.6 3.5e-07 30.0 0.4 1.4 1 1 0 1 1 1 1 Sybindin-like family TFIIA PF03153.8 OAJ32338.1 - 9.2 6.0 8.6 15 5.3 6.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ODV-E18 PF10717.4 OAJ32339.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 SMK-1 PF04802.10 OAJ32340.1 - 4.1e-72 241.7 2.8 1.2e-71 240.2 1.9 1.8 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Cys_rich_CPCC PF14206.1 OAJ32341.1 - 0.14 11.7 2.5 0.19 11.2 1.8 1.3 1 0 0 1 1 1 0 Cysteine-rich CPCC DUF4336 PF14234.1 OAJ32343.1 - 0.0012 18.0 0.0 0.18 10.9 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Heme_oxygenase PF01126.15 OAJ32344.1 - 3.9e-08 33.1 0.0 3.8e-06 26.6 0.0 2.9 3 1 0 3 3 3 2 Heme oxygenase Ribosomal_S26e PF01283.14 OAJ32345.1 - 1.3e-51 173.5 9.3 1.7e-51 173.2 6.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 OAJ32345.1 - 0.0041 17.4 1.8 0.0099 16.2 1.2 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 OAJ32345.1 - 0.037 14.0 0.4 0.088 12.8 0.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 OAJ32345.1 - 0.038 13.8 2.9 0.094 12.5 2.0 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain DUF1918 PF08940.6 OAJ32345.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Fer4_16 PF13484.1 OAJ32345.1 - 0.11 13.2 1.9 0.23 12.2 1.3 1.6 1 1 0 1 1 1 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 OAJ32345.1 - 0.12 12.6 2.3 0.74 10.1 2.0 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.2 OAJ32345.1 - 0.12 12.2 1.3 0.12 12.2 0.9 1.8 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.22 OAJ32345.1 - 0.14 11.8 0.7 0.14 11.8 0.5 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain SCA7 PF08313.7 OAJ32345.1 - 0.21 11.2 0.3 0.21 11.2 0.2 1.9 2 0 0 2 2 2 0 SCA7, zinc-binding domain Fer4_18 PF13746.1 OAJ32345.1 - 4.1 7.9 7.5 3.6 8.0 2.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain MFS_1 PF07690.11 OAJ32348.1 - 2.9e-09 36.0 19.8 2.9e-09 36.0 13.7 3.5 1 1 0 2 2 2 1 Major Facilitator Superfamily PSRT PF07636.6 OAJ32348.1 - 0.11 11.9 5.1 0.31 10.5 3.5 1.7 1 0 0 1 1 1 0 PSRT adh_short PF00106.20 OAJ32349.1 - 6.8e-16 58.6 0.1 1.1e-15 57.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ32349.1 - 6.1e-07 29.2 0.0 1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ32349.1 - 9.5e-06 25.5 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAJ32349.1 - 0.017 15.1 0.7 0.04 13.9 0.5 1.8 1 1 0 1 1 1 0 NADH(P)-binding FAM165 PF14981.1 OAJ32349.1 - 0.022 14.2 0.4 0.041 13.3 0.2 1.4 1 0 0 1 1 1 0 FAM165 family 3HCDH_N PF02737.13 OAJ32349.1 - 0.03 13.9 0.1 0.044 13.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TFIIB PF00382.14 OAJ32349.1 - 0.034 13.9 0.1 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Shikimate_DH PF01488.15 OAJ32349.1 - 0.042 13.9 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 OAJ32349.1 - 0.049 12.7 0.1 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IclR PF01614.13 OAJ32349.1 - 0.087 12.5 1.0 0.19 11.4 0.2 1.8 2 0 0 2 2 2 0 Bacterial transcriptional regulator Epimerase PF01370.16 OAJ32349.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pro_isomerase PF00160.16 OAJ32350.1 - 4.2e-47 160.2 0.1 1.8e-46 158.1 0.0 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 OAJ32350.1 - 6e-12 44.9 2.9 0.0011 18.7 0.0 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat Prefoldin_2 PF01920.15 OAJ32351.1 - 3.8e-17 61.9 7.7 4.9e-17 61.6 5.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.2 OAJ32351.1 - 0.027 14.2 2.2 0.027 14.2 1.6 2.1 2 0 0 2 2 2 0 Tropomyosin like RasGAP_C PF03836.10 OAJ32351.1 - 0.045 13.4 0.7 0.045 13.4 0.5 2.7 2 1 1 3 3 3 0 RasGAP C-terminus Snapin_Pallidin PF14712.1 OAJ32351.1 - 0.093 13.0 1.0 0.093 13.0 0.7 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Sec23_trunk PF04811.10 OAJ32351.1 - 0.11 11.8 1.3 0.23 10.7 0.9 1.5 1 1 0 1 1 1 0 Sec23/Sec24 trunk domain Antimicrobial_3 PF08025.6 OAJ32351.1 - 0.27 10.9 1.3 0.7 9.6 0.9 1.7 1 0 0 1 1 1 0 Spider antimicrobial peptide Init_tRNA_PT PF04179.7 OAJ32351.1 - 0.85 8.4 4.7 0.89 8.3 3.3 1.0 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase NPV_P10 PF05531.7 OAJ32351.1 - 1.2 9.4 3.8 1.5 9.0 0.1 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cortex-I_coil PF09304.5 OAJ32351.1 - 1.5 8.9 7.9 0.62 10.1 0.6 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil ADIP PF11559.3 OAJ32351.1 - 2.4 8.0 10.5 4.5 7.1 1.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.6 OAJ32351.1 - 3.2 7.4 8.7 17 5.1 1.5 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CCDC144C PF14915.1 OAJ32351.1 - 3.3 6.5 12.5 21 3.9 8.6 1.9 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region DUF4140 PF13600.1 OAJ32351.1 - 3.4 8.1 6.0 18 5.8 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Asp PF00026.18 OAJ32352.1 - 3.1e-41 141.6 0.0 8.3e-41 140.2 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ32352.1 - 0.00014 21.9 0.2 0.00014 21.9 0.2 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAJ32352.1 - 0.0063 16.9 0.1 2.1 8.9 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease Abhydrolase_6 PF12697.2 OAJ32353.1 - 2.5e-24 86.4 0.6 4.4e-24 85.6 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ32353.1 - 3.4e-22 79.1 0.0 3.6e-21 75.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ32353.1 - 1.4e-13 50.8 0.0 1.1e-12 47.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 OAJ32353.1 - 0.0074 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 OAJ32353.1 - 0.091 12.6 0.0 0.22 11.4 0.0 1.6 1 1 0 1 1 1 0 Putative lysophospholipase Peptidase_S28 PF05577.7 OAJ32353.1 - 0.22 10.0 0.0 0.36 9.3 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 AAA PF00004.24 OAJ32354.1 - 4e-44 150.0 0.1 9.6e-44 148.7 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAJ32354.1 - 7.2e-09 35.4 0.0 4.4e-08 32.9 0.1 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 OAJ32354.1 - 2.1e-07 31.0 0.1 5.6e-07 29.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 OAJ32354.1 - 2.6e-06 27.5 0.1 1.2e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ32354.1 - 3.2e-06 27.3 0.5 0.0021 18.1 0.0 2.8 2 1 1 3 3 2 1 AAA domain DUF815 PF05673.8 OAJ32354.1 - 5.9e-06 25.3 0.0 3e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 OAJ32354.1 - 0.00034 20.5 0.1 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ32354.1 - 0.00051 19.7 0.1 0.0017 18.0 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 OAJ32354.1 - 0.00056 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 OAJ32354.1 - 0.0012 18.6 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 NTPase RuvB_N PF05496.7 OAJ32354.1 - 0.0012 17.8 0.0 0.0027 16.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 OAJ32354.1 - 0.0013 19.4 0.1 0.0072 17.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 OAJ32354.1 - 0.0026 16.5 0.0 0.0057 15.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 OAJ32354.1 - 0.0027 17.6 0.0 0.0073 16.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 OAJ32354.1 - 0.003 17.2 0.1 0.045 13.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 OAJ32354.1 - 0.0033 17.7 0.0 0.018 15.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAJ32354.1 - 0.0035 17.2 0.0 0.011 15.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain Arch_ATPase PF01637.13 OAJ32354.1 - 0.0042 16.8 0.6 0.12 12.0 0.0 2.9 3 1 1 4 4 3 1 Archaeal ATPase AAA_11 PF13086.1 OAJ32354.1 - 0.0042 16.7 0.0 0.029 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 OAJ32354.1 - 0.0051 16.9 0.0 0.013 15.6 0.0 1.7 2 0 0 2 2 1 1 RNA helicase Mg_chelatase PF01078.16 OAJ32354.1 - 0.0069 15.5 0.1 0.019 14.1 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 OAJ32354.1 - 0.0082 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 OAJ32354.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 OAJ32354.1 - 0.01 15.4 0.0 0.029 14.0 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 OAJ32354.1 - 0.012 15.0 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Bac_DnaA PF00308.13 OAJ32354.1 - 0.02 14.5 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_24 PF13479.1 OAJ32354.1 - 0.021 14.3 0.2 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAJ32354.1 - 0.031 13.6 4.2 0.047 13.0 0.1 2.6 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.1 OAJ32354.1 - 0.047 14.0 1.1 0.58 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 OAJ32354.1 - 0.055 12.3 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 OAJ32354.1 - 0.13 11.7 0.1 1.8 7.9 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 OAJ32354.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_60s PF00428.14 OAJ32357.1 - 0.006 16.9 2.9 0.013 15.9 2.0 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein BSP_II PF05432.6 OAJ32357.1 - 0.056 12.7 6.1 0.069 12.4 4.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 OAJ32357.1 - 0.58 9.2 5.4 0.76 8.8 3.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PBP1_TM PF14812.1 OAJ32357.1 - 2.5 8.4 9.5 1 9.7 2.9 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3381 PF11861.3 OAJ32357.1 - 4.3 6.8 8.5 0.25 10.8 2.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) zf-RING_2 PF13639.1 OAJ32358.1 - 4.5e-08 32.7 13.4 7.2e-08 32.1 9.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ32358.1 - 5.6e-07 29.4 15.1 9.2e-07 28.7 10.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ32358.1 - 2.5e-06 27.0 13.0 4.2e-06 26.3 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ32358.1 - 8.6e-06 25.3 10.7 1.5e-05 24.6 7.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAJ32358.1 - 1.6e-05 24.5 14.3 2.4e-05 23.9 9.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAJ32358.1 - 0.0028 17.4 13.0 0.0053 16.6 9.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING TMF_DNA_bd PF12329.3 OAJ32358.1 - 0.017 14.8 1.0 0.034 13.9 0.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.3 OAJ32358.1 - 0.048 12.9 0.3 0.082 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-rbx1 PF12678.2 OAJ32358.1 - 0.048 13.7 11.5 0.1 12.7 7.9 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger YlqD PF11068.3 OAJ32358.1 - 0.097 12.7 1.4 0.17 11.9 1.0 1.3 1 0 0 1 1 1 0 YlqD protein DUF812 PF05667.6 OAJ32358.1 - 1.2 7.5 7.7 0.19 10.1 2.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF812) zf-RING_6 PF14835.1 OAJ32358.1 - 1.4 8.7 9.3 2.4 7.9 6.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 OAJ32358.1 - 7.3 6.2 12.2 12 5.5 8.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain WD40 PF00400.27 OAJ32359.1 - 1.2e-19 69.4 6.4 6.6e-05 22.6 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 OAJ32359.1 - 0.011 13.8 2.4 0.42 8.6 0.4 2.9 2 1 0 2 2 2 0 Nucleoporin Nup120/160 DUF1241 PF06840.6 OAJ32359.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Pro_isomerase PF00160.16 OAJ32360.1 - 3.7e-44 150.6 0.0 5.6e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 OAJ32360.1 - 5.6e-08 32.3 3.9 0.0019 17.7 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 OAJ32360.1 - 0.00021 20.9 5.7 0.22 11.5 0.5 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ32360.1 - 0.47 10.1 2.7 7.5 6.3 0.2 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Pex14_N PF04695.8 OAJ32362.1 - 3.1 7.8 11.4 3.6 7.6 2.8 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region COG4 PF08318.7 OAJ32364.1 - 1.4e-44 152.2 0.0 4.7e-26 91.3 0.0 2.2 2 0 0 2 2 2 2 COG4 transport protein CK2S PF15011.1 OAJ32364.1 - 0.04 13.7 3.4 1.1 8.9 0.7 3.0 3 1 0 3 3 3 0 Casein Kinase 2 substrate Ras PF00071.17 OAJ32365.1 - 9.9e-65 216.8 0.8 1.2e-64 216.6 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ32365.1 - 6.9e-21 74.9 0.0 9.9e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ32365.1 - 1.9e-17 63.0 0.1 2.4e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ32365.1 - 2.6e-07 30.0 0.1 3e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 OAJ32365.1 - 2.7e-06 26.9 0.2 5e-06 26.0 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ32365.1 - 4.1e-05 23.5 0.0 6.6e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 OAJ32365.1 - 7.7e-05 21.9 0.1 9.3e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 OAJ32365.1 - 0.00089 19.3 0.0 0.0016 18.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 OAJ32365.1 - 0.0019 17.5 0.1 0.016 14.5 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.24 OAJ32365.1 - 0.0056 16.8 0.1 0.35 11.0 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ32365.1 - 0.016 15.2 0.2 0.047 13.6 0.1 2.0 1 1 1 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 OAJ32365.1 - 0.016 14.4 0.1 0.047 12.8 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 OAJ32365.1 - 0.036 13.8 0.0 0.088 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 OAJ32365.1 - 0.036 13.5 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 OAJ32365.1 - 0.074 12.5 0.0 1.2 8.6 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NAGLU PF05089.7 OAJ32365.1 - 0.092 11.4 0.0 0.16 10.6 0.0 1.5 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain G-alpha PF00503.15 OAJ32365.1 - 1.1 7.8 5.1 13 4.3 0.7 2.9 1 1 1 2 2 2 0 G-protein alpha subunit Abhydrolase_6 PF12697.2 OAJ32366.1 - 1.7e-21 77.1 0.0 2.2e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ32366.1 - 3.5e-16 59.2 0.0 5.6e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ32366.1 - 8.1e-15 54.4 0.0 1.7e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 OAJ32366.1 - 3.2e-05 23.6 0.0 0.00025 20.6 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAJ32366.1 - 8.7e-05 21.8 0.1 0.054 12.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.15 OAJ32366.1 - 0.00092 18.7 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.7 OAJ32366.1 - 0.0076 14.7 0.3 0.12 10.8 0.0 2.3 3 0 0 3 3 3 1 Acetyl xylan esterase (AXE1) DUF915 PF06028.6 OAJ32366.1 - 0.011 14.8 0.0 0.032 13.3 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.10 OAJ32366.1 - 0.027 13.4 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.8 OAJ32366.1 - 0.07 12.6 0.0 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 OAJ32366.1 - 0.16 11.5 0.0 0.49 9.9 0.0 1.8 3 0 0 3 3 3 0 PGAP1-like protein MFS_1 PF07690.11 OAJ32367.1 - 3.6e-22 78.5 45.6 3.1e-12 45.8 20.5 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Rep_fac-A_3 PF08661.6 OAJ32368.1 - 1.9e-27 95.3 0.3 2.1e-27 95.1 0.2 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Homeobox PF00046.24 OAJ32369.1 - 7.5e-19 67.0 1.5 1.1e-18 66.5 1.1 1.3 1 0 0 1 1 1 1 Homeobox domain Cyto_heme_lyase PF01265.12 OAJ32370.1 - 3.7e-72 243.0 0.2 8.4e-72 241.8 0.2 1.5 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase PX PF00787.19 OAJ32371.1 - 7.6e-22 77.2 0.6 1.9e-21 75.9 0.4 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 OAJ32371.1 - 1.1e-10 41.1 3.7 3e-07 29.9 0.5 2.5 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 OAJ32371.1 - 0.00088 18.8 1.8 0.89 9.0 0.1 3.1 3 0 0 3 3 3 2 BAR domain APC2 PF08672.6 OAJ32371.1 - 0.015 15.5 0.1 1.5 9.1 0.0 2.9 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 CAMP_factor PF07373.6 OAJ32371.1 - 0.028 13.9 0.0 0.67 9.4 0.0 2.2 2 0 0 2 2 2 0 CAMP factor (Cfa) Dynamitin PF04912.9 OAJ32371.1 - 0.098 11.4 1.7 0.11 11.3 0.2 1.6 2 0 0 2 2 2 0 Dynamitin tRNA-synt_1c PF00749.16 OAJ32372.1 - 3.1e-102 341.4 0.0 6e-102 340.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 OAJ32372.1 - 1.5e-29 102.6 0.0 2.5e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 OAJ32372.1 - 2.5e-29 102.1 0.0 8.9e-29 100.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 OAJ32372.1 - 3.2e-08 34.1 10.0 3.2e-08 34.1 6.9 3.2 3 1 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Ribosomal_S5 PF00333.15 OAJ32373.1 - 1.9e-28 98.0 2.2 2.1e-28 97.8 0.8 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 OAJ32373.1 - 1.2e-21 75.7 0.1 2.1e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain RNA_pol PF00940.14 OAJ32373.1 - 0.17 10.3 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 DNA-dependent RNA polymerase FoP_duplication PF13865.1 OAJ32373.1 - 7.9 7.0 7.2 18 5.8 5.0 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 zf-Apc11 PF12861.2 OAJ32374.1 - 4.9e-31 106.4 9.1 6.3e-31 106.0 6.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 OAJ32374.1 - 3.3e-26 91.2 8.8 4.4e-26 90.7 6.1 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 OAJ32374.1 - 1.7e-06 27.7 14.9 5.7e-06 26.0 10.3 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 OAJ32374.1 - 1.7e-05 24.3 11.5 6.5e-05 22.5 8.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ32374.1 - 0.0032 17.4 12.0 0.064 13.2 8.3 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ32374.1 - 0.075 12.7 12.9 0.68 9.6 8.9 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 OAJ32374.1 - 0.55 10.2 9.8 1.4 8.9 6.8 1.8 1 1 0 1 1 1 0 RING-like domain zf-HC5HC2H_2 PF13832.1 OAJ32374.1 - 0.68 9.9 8.9 0.39 10.7 4.9 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-Nse PF11789.3 OAJ32374.1 - 1.4 8.5 6.5 2.4 7.7 4.5 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 OAJ32374.1 - 3.7 7.6 10.6 17 5.5 7.4 2.1 1 1 0 1 1 1 0 RING-variant domain TAFII28 PF04719.9 OAJ32375.1 - 9.6e-24 83.0 0.0 1.3e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF572 PF04502.8 OAJ32375.1 - 0.2 10.8 2.8 0.28 10.3 1.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) M_domain PF12938.2 OAJ32375.1 - 3.9 7.2 11.7 6.6 6.4 8.1 1.3 1 0 0 1 1 1 0 M domain of GW182 Arrestin_C PF02752.17 OAJ32376.1 - 1.2e-14 54.6 0.0 6.7e-14 52.1 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 OAJ32376.1 - 6e-08 32.6 0.0 3.3e-05 23.7 0.0 2.6 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Serglycin PF04360.7 OAJ32376.1 - 0.46 10.2 0.0 0.46 10.2 0.0 6.7 6 3 0 6 6 6 0 Serglycin SKIP_SNW PF02731.10 OAJ32377.1 - 9.3e-65 216.8 1.8 9.3e-65 216.8 1.2 2.1 3 0 0 3 3 3 1 SKIP/SNW domain POT1 PF02765.12 OAJ32378.1 - 3.3e-11 43.3 0.0 1e-10 41.7 0.0 1.8 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 RFX_DNA_binding PF02257.10 OAJ32379.1 - 1.4e-16 60.4 0.0 2.4e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain TPR_11 PF13414.1 OAJ32380.1 - 1e-27 95.5 3.5 1e-12 47.4 0.0 3.7 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 OAJ32380.1 - 4.4e-19 67.2 0.1 4.1e-05 23.0 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ32380.1 - 1.2e-14 52.9 1.4 0.00063 19.4 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ32380.1 - 4.2e-13 48.3 1.5 0.012 15.7 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ32380.1 - 1.6e-10 40.7 4.3 8.6e-06 25.6 0.0 4.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ32380.1 - 3.1e-10 39.0 0.1 0.02 14.6 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ32380.1 - 2.3e-09 37.0 10.7 0.012 16.1 0.0 6.8 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ32380.1 - 3.8e-07 30.6 0.0 0.00015 22.3 0.0 6.4 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ32380.1 - 8.8e-07 29.1 3.5 0.28 11.5 0.0 4.7 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ32380.1 - 1.7e-06 27.4 0.1 0.25 11.1 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ32380.1 - 0.00022 21.0 3.9 1.4 8.8 0.0 4.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ32380.1 - 0.0098 15.9 9.0 0.073 13.1 0.4 4.8 3 2 1 5 5 5 2 Tetratricopeptide repeat 2OG-FeII_Oxy_2 PF13532.1 OAJ32381.1 - 5.7e-15 55.6 0.0 8.2e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ32381.1 - 2.6e-06 27.6 0.0 4.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ATP11 PF06644.6 OAJ32382.1 - 2.8e-63 213.9 0.0 6.7e-63 212.6 0.0 1.6 1 1 0 1 1 1 1 ATP11 protein MHC2-interact PF09307.5 OAJ32382.1 - 0.058 13.1 2.3 1.1 9.0 0.3 2.8 3 1 0 3 3 3 0 CLIP, MHC2 interacting CDC27 PF09507.5 OAJ32382.1 - 0.094 11.9 12.1 0.13 11.4 8.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PepSY_2 PF13670.1 OAJ32382.1 - 0.65 9.9 5.8 0.37 10.7 0.9 2.5 1 1 2 3 3 3 0 Peptidase propeptide and YPEB domain FUSC PF04632.7 OAJ32382.1 - 2.4 6.4 8.0 3.3 6.0 5.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sel1 PF08238.7 OAJ32384.1 - 1.2e-16 60.7 26.3 0.0019 18.7 0.1 8.8 9 0 0 9 9 9 5 Sel1 repeat TPR_11 PF13414.1 OAJ32384.1 - 0.0018 17.9 2.5 2.8 7.6 0.0 4.2 5 0 0 5 5 5 2 TPR repeat TPR_1 PF00515.23 OAJ32384.1 - 0.0081 15.7 3.7 0.24 11.0 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ32384.1 - 0.017 15.0 1.0 0.58 10.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ32384.1 - 0.046 13.5 0.6 0.94 9.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ32384.1 - 0.084 12.8 0.0 0.084 12.8 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ32384.1 - 0.47 10.3 0.0 0.47 10.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ32384.1 - 3.8 8.1 6.7 86 3.9 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Peptidase_M14 PF00246.19 OAJ32385.1 - 1.3e-52 179.2 0.0 7.6e-34 117.5 0.0 3.2 2 1 0 2 2 2 2 Zinc carboxypeptidase Ribosom_S12_S23 PF00164.20 OAJ32386.1 - 2e-38 130.5 1.0 2.3e-38 130.3 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L27e PF01777.13 OAJ32387.1 - 4.4e-38 129.2 1.3 6.8e-38 128.6 0.9 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 OAJ32387.1 - 0.00017 21.1 0.6 0.00039 20.0 0.4 1.6 1 0 0 1 1 1 1 KOW motif Iso_dh PF00180.15 OAJ32388.1 - 1.2e-117 392.8 0.0 1.4e-117 392.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase YebG PF07130.7 OAJ32388.1 - 0.1 12.2 0.1 14 5.4 0.0 2.5 2 0 0 2 2 2 0 YebG protein DUF2034 PF10356.4 OAJ32389.1 - 8.7e-18 64.1 5.8 1.5e-17 63.3 0.0 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 OAJ32389.1 - 4.5e-06 26.4 0.0 1.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Restriction endonuclease MSA_2 PF00985.12 OAJ32389.1 - 0.013 15.6 1.9 0.013 15.6 1.3 1.8 2 0 0 2 2 2 0 Merozoite Surface Antigen 2 (MSA-2) family Diphtheria_T PF02764.9 OAJ32389.1 - 0.32 10.7 1.5 0.55 9.9 1.0 1.3 1 0 0 1 1 1 0 Diphtheria toxin, T domain AT_hook PF02178.14 OAJ32389.1 - 1.2 9.0 18.2 0.27 11.0 1.1 4.1 3 0 0 3 3 3 0 AT hook motif Euplotes_phero PF05842.6 OAJ32389.1 - 2.1 8.7 7.6 4 7.8 5.3 1.4 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein Cmc1 PF08583.5 OAJ32393.1 - 2.3e-10 40.0 1.8 2.9e-10 39.7 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Barwin PF00967.12 OAJ32393.1 - 0.061 12.9 0.4 0.079 12.6 0.2 1.3 1 1 0 1 1 1 0 Barwin family F-box-like PF12937.2 OAJ32394.1 - 0.00083 19.0 0.3 0.0019 17.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like Pyr_redox_2 PF07992.9 OAJ32395.1 - 6e-25 88.2 0.0 5e-09 36.3 0.0 4.1 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ32395.1 - 2e-13 50.5 0.0 3.9e-08 33.5 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAJ32395.1 - 8.2e-07 29.2 0.0 0.0017 18.4 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 OAJ32395.1 - 0.0066 16.6 0.0 0.35 11.1 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding TrkA_N PF02254.13 OAJ32395.1 - 0.0099 15.8 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_8 PF13450.1 OAJ32395.1 - 0.026 14.5 0.0 11 6.1 0.0 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain UQ_con PF00179.21 OAJ32395.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme ACPS PF01648.15 OAJ32396.1 - 3.5e-08 33.2 0.0 1e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Dak1 PF02733.12 OAJ32400.1 - 6.3e-87 291.1 0.6 1.4e-86 290.0 0.4 1.5 1 1 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 OAJ32400.1 - 4.3e-37 127.4 5.0 1e-36 126.2 3.5 1.6 1 0 0 1 1 1 1 DAK2 domain DOT1 PF08123.8 OAJ32400.1 - 0.17 11.1 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 GPI-anchored PF10342.4 OAJ32401.1 - 1.2e-11 44.9 0.1 2.6e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NTF2 PF02136.15 OAJ32401.1 - 0.093 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain GnsAB PF08178.6 OAJ32401.1 - 0.17 11.5 0.1 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 GnsA/GnsB family SKN1 PF03935.10 OAJ32402.1 - 3.5e-175 582.9 0.0 4.5e-175 582.5 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 OAJ32402.1 - 0.0015 17.8 0.0 0.027 13.7 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Peptidase_S28 PF05577.7 OAJ32403.1 - 2.4e-38 131.8 0.5 2e-33 115.6 0.0 2.9 3 0 0 3 3 3 2 Serine carboxypeptidase S28 HEV_ORF1 PF02444.11 OAJ32403.1 - 0.13 12.4 0.9 0.67 10.1 0.0 2.3 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) SRP-alpha_N PF04086.8 OAJ32404.1 - 4.3e-47 160.8 0.0 6.6e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 OAJ32404.1 - 1.2e-45 155.4 0.0 1.3e-28 99.7 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain CbiA PF01656.18 OAJ32404.1 - 1.7e-07 30.8 0.0 3.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 OAJ32404.1 - 2.3e-06 27.6 0.0 8.2e-06 25.8 0.0 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.1 OAJ32404.1 - 0.0032 17.4 1.8 0.047 13.6 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 OAJ32404.1 - 0.004 17.2 0.1 0.02 15.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 OAJ32404.1 - 0.012 15.2 0.0 0.035 13.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 OAJ32404.1 - 0.021 13.6 0.0 0.17 10.6 0.0 2.3 3 0 0 3 3 3 0 ArgK protein Fer4_NifH PF00142.13 OAJ32404.1 - 0.098 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.10 OAJ32404.1 - 0.16 10.9 0.0 3.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Anion-transporting ATPase NTPase_1 PF03266.10 OAJ32404.1 - 0.16 11.6 0.0 1 9.0 0.0 2.1 1 1 0 1 1 1 0 NTPase Sigma70_ner PF04546.8 OAJ32404.1 - 3.9 7.0 5.7 7.3 6.1 3.9 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region START PF01852.14 OAJ32405.1 - 0.017 14.4 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 START domain Lin-8 PF03353.10 OAJ32405.1 - 1.1 8.4 4.9 2 7.6 3.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2419 PF10343.4 OAJ32406.1 - 1.1e-06 28.0 0.0 0.00024 20.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2419) CGI-121 PF08617.5 OAJ32407.1 - 8.2e-27 93.8 0.0 1.2e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Kinase binding protein CGI-121 RCC1_2 PF13540.1 OAJ32408.1 - 0.00023 20.6 13.2 0.12 12.0 0.8 4.9 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 OAJ32408.1 - 0.0015 18.7 6.3 21 5.4 0.0 6.0 6 0 0 6 6 6 1 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 OAJ32408.1 - 0.01 15.5 0.2 0.028 14.1 0.1 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 OAJ32408.1 - 0.053 13.1 0.1 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 F-box domain AMP-binding PF00501.23 OAJ32409.1 - 8.4e-90 301.1 0.0 1e-89 300.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ32409.1 - 2.7e-09 37.8 0.2 7.3e-09 36.4 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Menin PF05053.8 OAJ32409.1 - 4.4 5.3 5.8 6.4 4.8 4.0 1.1 1 0 0 1 1 1 0 Menin RPN7 PF10602.4 OAJ32410.1 - 2e-43 147.8 0.0 9.7e-43 145.5 0.0 2.1 2 1 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 OAJ32410.1 - 3.8e-13 49.6 0.0 8.3e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 PCI domain EAP30 PF04157.11 OAJ32410.1 - 0.04 13.0 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family DUF1242 PF06842.7 OAJ32411.1 - 3.6e-18 64.7 2.1 4.8e-18 64.3 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Jag_N PF14804.1 OAJ32411.1 - 0.076 13.0 0.3 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 Jag N-terminus LSR PF05624.9 OAJ32411.1 - 0.53 10.0 3.0 0.22 11.3 0.5 1.6 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) TPR_11 PF13414.1 OAJ32412.1 - 2e-18 65.7 1.7 5.2e-15 54.8 0.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 OAJ32412.1 - 1.1e-13 50.1 1.0 0.0015 18.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ32412.1 - 2.9e-11 42.3 1.3 0.0062 16.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ32412.1 - 2.6e-06 27.6 0.1 0.001 19.3 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ32412.1 - 4e-06 26.8 0.4 5.9e-06 26.3 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 OAJ32412.1 - 9.8e-05 22.9 1.0 0.22 12.2 0.0 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ32412.1 - 0.0024 18.3 1.6 0.59 10.9 1.5 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ32412.1 - 0.0029 17.6 0.6 0.66 10.3 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ32412.1 - 0.003 17.2 0.3 0.75 9.7 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ32412.1 - 0.0031 17.3 0.5 0.41 10.6 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat HHH_8 PF14716.1 OAJ32412.1 - 0.025 14.7 0.3 4.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain TPR_6 PF13174.1 OAJ32412.1 - 0.16 12.4 1.6 23 5.7 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MmgE_PrpD PF03972.9 OAJ32413.1 - 9.1e-99 330.6 4.6 4.2e-52 176.8 0.2 2.0 1 1 1 2 2 2 2 MmgE/PrpD family HSP70 PF00012.15 OAJ32415.1 - 3.4e-22 78.1 1.5 3.7e-22 77.9 1.0 1.0 1 0 0 1 1 1 1 Hsp70 protein ASF1_hist_chap PF04729.8 OAJ32415.1 - 0.0001 21.9 0.0 0.00021 20.9 0.0 1.5 1 0 0 1 1 1 1 ASF1 like histone chaperone SSF PF00474.12 OAJ32416.1 - 1.1e-12 47.3 25.3 4.5e-12 45.3 17.6 2.0 1 1 0 1 1 1 1 Sodium:solute symporter family Ribosomal_S19 PF00203.16 OAJ32417.1 - 3.5e-24 84.2 0.0 4.4e-24 83.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 ChAPs PF09295.5 OAJ32418.1 - 6.3e-152 505.9 0.0 1.4e-151 504.8 0.0 1.5 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) Apc3 PF12895.2 OAJ32418.1 - 0.00014 21.8 0.2 0.13 12.4 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 OAJ32418.1 - 0.00027 21.1 0.0 0.19 12.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ32418.1 - 0.012 15.2 7.0 0.032 13.8 0.0 3.7 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.12 OAJ32418.1 - 0.012 15.4 0.3 4.9 7.3 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 OAJ32419.1 - 1.1e-64 218.0 0.0 1.6e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ32419.1 - 8.6e-29 100.3 0.0 1.1e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ32419.1 - 4.8e-07 29.0 0.0 8.7e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ32419.1 - 0.045 13.4 0.0 1.7 8.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ32419.1 - 0.063 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 TFIIA PF03153.8 OAJ32419.1 - 2.7 7.7 7.7 3.7 7.3 5.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.3 OAJ32419.1 - 9.5 5.3 20.7 15 4.6 14.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SET PF00856.23 OAJ32420.1 - 1.1e-25 90.8 0.3 8.4e-25 87.9 0.0 2.8 3 0 0 3 3 3 1 SET domain N-SET PF11764.3 OAJ32420.1 - 2.5e-14 53.5 0.3 2.5e-14 53.5 0.2 2.7 2 1 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N BUD22 PF09073.5 OAJ32420.1 - 0.086 11.8 18.3 0.4 9.6 12.7 2.1 1 0 0 1 1 1 0 BUD22 DDE_Tnp_2 PF04693.7 OAJ32420.1 - 1.1 8.2 0.0 1.6 7.6 0.0 1.1 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 Nop14 PF04147.7 OAJ32420.1 - 5.6 4.7 15.2 9.8 3.9 10.6 1.3 1 0 0 1 1 1 0 Nop14-like family ProRS-C_1 PF09180.6 OAJ32421.1 - 3.3e-25 87.7 1.8 7.1e-25 86.7 1.2 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 OAJ32421.1 - 2.1e-23 82.8 0.0 6.5e-23 81.1 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ32421.1 - 8.2e-16 57.7 0.0 1.7e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain TraC_F_IV PF11130.3 OAJ32421.1 - 0.051 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer SNF2_N PF00176.18 OAJ32422.1 - 7.8e-66 221.8 0.2 1.1e-65 221.4 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ32422.1 - 3.9e-14 52.2 0.0 1.1e-13 50.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ32422.1 - 1.1e-06 28.6 0.0 3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ32422.1 - 1.1e-05 25.0 0.0 2.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase UBA PF00627.26 OAJ32422.1 - 3.1e-05 23.6 0.1 8.6e-05 22.2 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain UCH PF00443.24 OAJ32423.1 - 1.3e-38 132.7 0.0 6.9e-38 130.2 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ32423.1 - 5.3e-08 32.6 0.0 0.14 11.5 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase HORMA PF02301.13 OAJ32424.1 - 1.1e-18 67.4 0.0 1.3e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 HORMA domain Sod_Fe_C PF02777.13 OAJ32425.1 - 1.1e-34 118.4 0.7 1.9e-34 117.6 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 OAJ32425.1 - 5.1e-32 109.9 5.1 1.1e-31 108.9 3.6 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AsmA_1 PF13109.1 OAJ32425.1 - 0.0038 16.5 0.1 0.037 13.2 0.0 2.2 1 1 2 3 3 3 1 AsmA-like C-terminal region PAT1 PF09770.4 OAJ32426.1 - 0.0088 14.3 21.6 0.012 13.9 15.0 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Vps54 PF07928.7 OAJ32427.1 - 6.8e-53 178.4 1.5 1.8e-52 177.0 1.1 1.8 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 OAJ32427.1 - 1.9e-05 23.6 2.6 1.9e-05 23.6 1.8 2.1 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Inhibitor_I71 PF12628.2 OAJ32427.1 - 2.8 7.5 6.1 1.3e+02 2.1 0.0 2.6 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor MRG PF05712.8 OAJ32430.1 - 1.7e-54 183.6 0.0 2.6e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 OAJ32430.1 - 3.3e-10 39.5 0.0 7.3e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Hep_59 PF07052.6 OAJ32430.1 - 0.02 15.2 1.5 2.4 8.5 0.0 2.7 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 RVT_1 PF00078.22 OAJ32431.1 - 9.3e-12 44.7 0.0 1.4e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAJ32431.1 - 0.013 15.8 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 RNase H DUF2457 PF10446.4 OAJ32433.1 - 0.099 11.3 7.8 0.091 11.4 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 OAJ32433.1 - 0.74 9.0 6.8 0.75 8.9 4.7 1.0 1 0 0 1 1 1 0 NOA36 protein TFIIF_alpha PF05793.7 OAJ32433.1 - 1.1 7.5 7.9 1.2 7.4 5.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cwf_Cwc_15 PF04889.7 OAJ32433.1 - 1.5 8.4 8.5 1.7 8.3 5.9 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 OAJ32433.1 - 1.9 7.9 8.6 2.2 7.8 6.0 1.1 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 OAJ32433.1 - 3.1 8.1 8.2 3.9 7.8 5.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 OAJ32433.1 - 3.9 7.7 12.2 4.5 7.5 8.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ank_2 PF12796.2 OAJ32434.1 - 3e-34 117.2 0.0 4.8e-14 52.4 0.0 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ32434.1 - 6.4e-32 109.3 1.3 2.8e-13 49.9 0.0 4.8 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 OAJ32434.1 - 6.6e-32 107.7 2.2 9.3e-11 40.9 0.0 5.7 5 1 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 OAJ32434.1 - 3e-28 97.1 1.0 3.5e-10 39.7 0.0 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ32434.1 - 2.5e-26 89.1 0.1 8.7e-08 31.6 0.0 5.8 5 1 1 6 6 6 4 Ankyrin repeat Cytochrom_C1 PF02167.10 OAJ32435.1 - 1.1e-86 289.9 0.0 1.5e-86 289.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 OAJ32435.1 - 0.00061 19.8 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 OAJ32435.1 - 0.033 14.9 0.2 0.15 12.9 0.1 2.3 2 1 0 2 2 2 0 Cytochrome c CAP_GLY PF01302.20 OAJ32436.1 - 2.5e-27 94.3 0.7 3.7e-27 93.8 0.5 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 OAJ32436.1 - 1.1e-11 44.7 0.0 3.5e-11 43.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain HMA PF00403.21 OAJ32437.1 - 7.6e-18 64.4 0.9 8.8e-18 64.2 0.6 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Alba PF01918.16 OAJ32437.1 - 0.05 13.1 0.1 0.085 12.4 0.0 1.6 2 0 0 2 2 2 0 Alba Gp37 PF09646.5 OAJ32437.1 - 0.097 12.1 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Gp37 protein WD40 PF00400.27 OAJ32439.1 - 1.4e-47 157.9 17.9 7.6e-11 41.4 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Rtf2 PF04641.7 OAJ32440.1 - 0.00014 21.1 0.1 0.0003 20.0 0.1 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 OAJ32440.1 - 0.0019 17.9 0.1 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAJ32440.1 - 0.0047 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ32440.1 - 0.023 14.4 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger CDC45 PF02724.9 OAJ32440.1 - 0.27 9.2 0.5 0.37 8.7 0.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M22 PF00814.20 OAJ32441.1 - 5.1e-66 222.9 0.1 6.7e-66 222.5 0.1 1.2 1 0 0 1 1 1 1 Glycoprotease family Adaptin_N PF01602.15 OAJ32442.1 - 1.2e-101 340.6 0.0 1.7e-101 340.1 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 OAJ32442.1 - 3e-53 179.7 0.0 6e-53 178.7 0.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 OAJ32442.1 - 1.7e-13 50.6 5.8 0.0012 19.0 0.1 5.8 2 2 5 7 7 7 4 HEAT repeats HEAT PF02985.17 OAJ32442.1 - 0.00089 19.1 8.6 0.77 10.0 0.1 6.4 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.2 OAJ32442.1 - 0.012 15.4 3.1 7.1 6.4 0.1 3.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.11 OAJ32442.1 - 0.021 15.2 3.4 23 5.8 0.0 5.2 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat OmpW PF03922.9 OAJ32443.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 OmpW family Phosphoesterase PF04185.9 OAJ32444.1 - 7.3e-25 87.9 2.2 9.8e-25 87.5 1.5 1.2 1 0 0 1 1 1 1 Phosphoesterase family DDE_3 PF13358.1 OAJ32445.1 - 1.4e-14 54.0 0.0 2.7e-14 53.1 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 OAJ32445.1 - 6.5e-05 23.0 0.0 9.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain AAA PF00004.24 OAJ32446.1 - 5.8e-18 65.3 0.0 3.3e-17 62.9 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 OAJ32446.1 - 0.00015 21.3 0.1 0.047 13.3 0.0 2.5 3 0 0 3 3 3 2 BCS1 N terminal AAA_22 PF13401.1 OAJ32446.1 - 0.088 12.9 0.0 0.44 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 OAJ32446.1 - 0.098 12.0 0.0 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain ADH_zinc_N PF00107.21 OAJ32448.1 - 2.1e-19 69.3 1.2 4.4e-19 68.3 0.8 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ32448.1 - 5.7e-10 40.1 0.2 1.2e-09 39.0 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ32448.1 - 0.00054 19.7 0.0 0.0029 17.3 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Nucleoporin_C PF03177.9 OAJ32449.1 - 5.5e-54 183.6 4.8 8.2e-54 183.1 3.3 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 OAJ32449.1 - 5.1e-16 58.4 0.0 1e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Nup133 N terminal like YkyA PF10368.4 OAJ32449.1 - 0.28 10.4 1.8 0.63 9.3 1.3 1.5 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF1682 PF07946.9 OAJ32450.1 - 1.2e-51 175.5 0.0 1.4e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Ank_2 PF12796.2 OAJ32451.1 - 2.6e-16 59.7 0.4 3.7e-13 49.6 0.2 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ32451.1 - 1.3e-14 53.1 3.1 3.9e-08 32.6 0.2 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 OAJ32451.1 - 1.3e-14 54.2 1.3 3.5e-10 40.1 0.3 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ32451.1 - 2.5e-11 42.6 0.8 7.6e-05 22.5 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 OAJ32451.1 - 1.7e-08 34.4 5.2 7e-06 26.1 0.4 4.4 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Nramp PF01566.13 OAJ32452.1 - 1e-88 297.5 26.7 1.7e-48 165.2 8.4 2.9 2 1 0 2 2 2 2 Natural resistance-associated macrophage protein CSF-1 PF05337.6 OAJ32452.1 - 0.048 12.9 0.4 1 8.6 0.0 2.3 2 0 0 2 2 2 0 Macrophage colony stimulating factor-1 (CSF-1) DUF572 PF04502.8 OAJ32453.1 - 0.83 8.8 4.1 1 8.5 2.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) FKBP_N PF01346.13 OAJ32453.1 - 0.96 9.5 6.0 1.9 8.5 4.2 1.5 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase TEX13 PF15186.1 OAJ32453.1 - 1.1 8.8 8.6 1.2 8.7 5.4 1.4 1 1 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF3835 PF12927.2 OAJ32454.1 - 1.1e-07 32.6 13.2 1e-05 26.3 0.1 4.8 5 1 1 6 6 6 2 Domain of unknown function (DUF3835) Secretogranin_V PF05281.6 OAJ32454.1 - 0.022 14.1 0.4 0.045 13.1 0.3 1.5 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) Nucleo_P87 PF07267.6 OAJ32454.1 - 0.44 9.1 1.2 0.78 8.3 0.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Myosin_tail_1 PF01576.14 OAJ32455.1 - 0.014 13.1 3.2 0.023 12.4 2.2 1.2 1 0 0 1 1 1 0 Myosin tail Transposase_mut PF00872.13 OAJ32455.1 - 0.35 9.3 2.8 0.61 8.5 1.9 1.3 1 0 0 1 1 1 0 Transposase, Mutator family Zn_clus PF00172.13 OAJ32456.1 - 1.8e-06 27.7 7.2 3.1e-06 27.0 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIE2_ALG10 PF04922.7 OAJ32457.1 - 4.9e-99 331.9 10.9 3.7e-74 250.0 6.8 2.0 2 0 0 2 2 2 2 DIE2/ALG10 family LexA_DNA_bind PF01726.11 OAJ32457.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain VRR_NUC PF08774.6 OAJ32458.1 - 3.9e-18 65.3 0.1 1.2e-17 63.7 0.0 1.9 1 0 0 1 1 1 1 VRR-NUC domain SET PF00856.23 OAJ32459.1 - 3.1e-19 69.8 1.0 1.9e-18 67.2 0.0 2.6 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.11 OAJ32459.1 - 2.3e-16 59.9 6.2 2.3e-16 59.9 4.3 2.1 2 0 0 2 2 2 1 Pre-SET motif YL1 PF05764.8 OAJ32460.1 - 6.9e-39 133.8 20.9 9.7e-39 133.4 14.5 1.2 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.6 OAJ32460.1 - 5.6e-09 35.3 0.0 9.4e-09 34.6 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF1484 PF07363.6 OAJ32460.1 - 2.2 8.6 4.4 2.9 8.2 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) Peptidase_M19 PF01244.16 OAJ32461.1 - 2.8e-93 312.3 0.0 3.2e-93 312.1 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Peptidase_M22 PF00814.20 OAJ32462.1 - 9.6e-74 248.2 0.0 5.2e-73 245.8 0.0 1.8 1 1 0 1 1 1 1 Glycoprotease family MOZ_SAS PF01853.13 OAJ32463.1 - 2.8e-79 264.7 0.1 3.8e-79 264.3 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family Ribosomal_60s PF00428.14 OAJ32463.1 - 0.013 15.9 0.5 0.013 15.9 0.3 3.9 3 1 0 3 3 3 0 60s Acidic ribosomal protein Adeno_terminal PF02459.10 OAJ32463.1 - 0.41 8.7 1.3 0.6 8.2 0.9 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein MIF4G PF02854.14 OAJ32464.1 - 7.1e-55 185.6 0.1 1e-28 100.1 0.0 3.3 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 OAJ32464.1 - 1.8e-23 83.1 13.6 5.2e-23 81.6 9.4 1.8 1 0 0 1 1 1 1 Up-frameshift suppressor 2 Daxx PF03344.10 OAJ32464.1 - 0.00021 19.9 16.9 0.00048 18.7 11.7 1.5 1 0 0 1 1 1 1 Daxx Family Nucleoplasmin PF03066.10 OAJ32464.1 - 0.033 13.6 14.6 0.092 12.2 10.1 1.7 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 OAJ32464.1 - 0.061 11.3 16.5 0.12 10.3 10.6 1.9 2 0 0 2 2 2 0 CDC45-like protein SOG2 PF10428.4 OAJ32465.1 - 4.2e-70 236.6 12.0 4.6e-55 187.0 0.0 3.7 4 0 0 4 4 4 2 RAM signalling pathway protein LRR_4 PF12799.2 OAJ32465.1 - 1.1e-12 47.2 5.9 2.7e-06 26.8 0.0 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ32465.1 - 1.4e-12 47.1 1.9 5.7e-09 35.5 0.1 3.0 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 OAJ32465.1 - 5e-07 28.8 2.0 0.91 9.7 0.0 5.3 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 OAJ32465.1 - 7.9e-05 22.2 0.4 8.3 7.1 0.0 4.9 4 0 0 4 4 4 2 Leucine rich repeat HDA2-3 PF11496.3 OAJ32465.1 - 0.032 13.0 0.6 0.053 12.3 0.0 1.6 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 LrgB PF04172.11 OAJ32466.1 - 3e-23 82.1 5.2 3e-23 82.1 3.6 2.1 2 1 1 3 3 3 1 LrgB-like family Pkr1 PF08636.5 OAJ32468.1 - 1.6e-18 66.4 1.9 2e-18 66.2 1.3 1.1 1 0 0 1 1 1 1 ER protein Pkr1 TGS PF02824.16 OAJ32469.1 - 3.4e-20 71.6 0.1 6.4e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 OAJ32469.1 - 6.5e-19 67.9 0.0 1.3e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ32469.1 - 2.4e-11 43.1 0.0 4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 OAJ32469.1 - 0.0011 18.7 0.2 0.045 13.5 0.0 2.4 1 1 1 2 2 2 1 Dynamin family MCM PF00493.18 OAJ32469.1 - 0.02 13.6 0.0 0.038 12.7 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family Miro PF08477.8 OAJ32469.1 - 0.026 15.0 0.0 0.063 13.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein DUF1002 PF06207.6 OAJ32469.1 - 0.069 12.4 0.7 0.12 11.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) AAA_16 PF13191.1 OAJ32469.1 - 0.092 12.7 0.1 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain zf-CCCH PF00642.19 OAJ32470.1 - 2.3e-07 30.3 2.2 4e-07 29.5 1.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_6 PF14259.1 OAJ32470.1 - 8.5e-07 28.8 0.0 1.9e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ32470.1 - 1.1e-06 28.4 0.1 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 OAJ32470.1 - 1.3e-06 28.3 0.0 3.1e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.1 OAJ32470.1 - 4.9e-05 23.0 0.0 9.2e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 OAJ32470.1 - 0.012 15.2 0.0 0.028 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ32470.1 - 0.45 10.3 0.0 0.45 10.3 0.0 2.5 4 0 0 4 4 4 0 RNA binding motif LSM PF01423.17 OAJ32471.1 - 4.4e-21 74.1 0.1 5.2e-21 73.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 OAJ32471.1 - 0.0004 20.2 0.0 0.00047 20.0 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain MFS_2 PF13347.1 OAJ32472.1 - 6.2e-11 41.3 1.0 6.2e-11 41.3 0.7 2.9 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.11 OAJ32472.1 - 0.0052 15.5 39.8 0.0026 16.5 24.1 2.8 2 2 0 2 2 2 1 Major Facilitator Superfamily PsaM PF07465.8 OAJ32472.1 - 3.7 7.2 6.5 0.28 10.8 0.8 1.9 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) Nuc_sug_transp PF04142.10 OAJ32473.1 - 2.4e-07 30.1 0.3 3.8e-07 29.4 0.2 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter CitMHS PF03600.11 OAJ32473.1 - 2.1e-05 23.3 0.0 4.2e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Citrate transporter EamA PF00892.15 OAJ32473.1 - 7.8e-05 22.7 3.4 7.8e-05 22.7 2.4 4.0 3 1 0 3 3 3 1 EamA-like transporter family TPT PF03151.11 OAJ32473.1 - 0.46 10.1 16.1 0.14 11.8 1.3 3.1 2 1 0 2 2 2 0 Triose-phosphate Transporter family CoxIIa PF08113.6 OAJ32473.1 - 2.6 7.8 7.3 0.16 11.7 0.6 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family Asp PF00026.18 OAJ32474.1 - 2.4e-48 165.0 7.0 7.5e-48 163.3 4.9 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 OAJ32474.1 - 0.00056 19.5 0.0 0.0018 17.8 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 OAJ32474.1 - 0.0024 17.8 4.4 0.017 15.0 2.5 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAJ32474.1 - 0.004 17.6 2.9 0.03 14.8 0.7 2.5 2 0 0 2 2 2 1 Aspartyl protease DUF89 PF01937.14 OAJ32476.1 - 2.4e-109 365.3 0.0 2.7e-109 365.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Response_reg PF00072.19 OAJ32477.1 - 3.1e-22 78.6 0.1 5.8e-16 58.4 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain E1_dh PF00676.15 OAJ32478.1 - 6.4e-108 360.0 0.4 8e-108 359.6 0.3 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 OAJ32478.1 - 0.00011 21.2 0.0 0.00022 20.2 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 OAJ32478.1 - 0.0017 17.9 3.9 0.0018 17.8 1.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain V-ATPase_H_N PF03224.9 OAJ32479.1 - 4.3e-79 265.8 0.0 1.4e-78 264.2 0.0 1.8 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 OAJ32479.1 - 5.3e-31 106.9 0.0 2.3e-30 104.9 0.0 2.2 1 1 0 1 1 1 1 V-ATPase subunit H HEAT PF02985.17 OAJ32479.1 - 0.0015 18.4 0.0 0.12 12.5 0.0 2.8 2 0 0 2 2 2 1 HEAT repeat ORC6 PF05460.8 OAJ32479.1 - 0.11 11.5 2.2 0.22 10.6 1.5 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF1785 PF08699.5 OAJ32480.1 - 5.2e-10 38.5 0.2 1.4e-09 37.1 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) SMC_N PF02463.14 OAJ32481.1 - 1.9e-27 95.9 0.0 6e-27 94.3 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAJ32481.1 - 7.9e-08 32.8 33.4 7.9e-08 32.8 23.2 5.4 3 2 0 3 3 3 1 AAA domain AAA_21 PF13304.1 OAJ32481.1 - 6.7e-06 26.2 0.5 0.13 12.1 0.2 3.0 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 OAJ32481.1 - 2.2e-05 23.6 2.0 2.2e-05 23.6 1.4 2.1 2 1 0 2 2 2 1 AAA ATPase domain Reo_sigmaC PF04582.7 OAJ32481.1 - 0.00019 20.7 8.8 0.69 9.0 0.7 4.4 3 1 1 4 4 4 3 Reovirus sigma C capsid protein SbcCD_C PF13558.1 OAJ32481.1 - 0.0009 19.1 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 OAJ32481.1 - 0.0015 18.0 0.3 0.0042 16.5 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 OAJ32481.1 - 0.0066 14.9 69.3 0.027 12.9 8.5 5.6 3 3 3 6 6 6 4 AAA domain Fer4_NifH PF00142.13 OAJ32481.1 - 1.5 7.9 6.2 0.33 10.0 0.5 2.4 2 1 1 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Rpr2 PF04032.11 OAJ32482.1 - 3.6e-13 49.2 0.0 5.9e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.2 OAJ32482.1 - 0.002 17.8 1.4 0.0038 16.9 0.9 1.4 1 0 0 1 1 1 1 Double zinc ribbon GFA PF04828.9 OAJ32482.1 - 0.019 14.8 0.5 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.11 OAJ32482.1 - 0.16 11.6 0.5 0.75 9.5 0.0 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit HLH PF00010.21 OAJ32483.1 - 5.4e-05 22.7 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain C2 PF00168.25 OAJ32485.1 - 3.3e-21 74.9 0.0 2.3e-14 53.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain Flagellin_IN PF07196.8 OAJ32485.1 - 0.069 13.1 0.5 0.37 10.8 0.0 2.3 2 0 0 2 2 2 0 Flagellin hook IN motif zf-C3HC4_3 PF13920.1 OAJ32486.1 - 0.00046 19.7 3.1 0.00083 18.9 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ32486.1 - 0.0015 18.3 7.0 0.0026 17.5 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 OAJ32486.1 - 0.0023 17.5 5.2 0.004 16.7 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ32486.1 - 0.014 15.4 6.6 0.026 14.5 4.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BTV_NS2 PF04514.7 OAJ32486.1 - 0.54 9.0 5.2 0.95 8.2 3.6 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 WD40 PF00400.27 OAJ32487.1 - 6.4e-13 48.0 1.9 0.7 9.8 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF1180 PF06679.7 OAJ32488.1 - 0.034 14.0 4.8 0.042 13.7 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) RhoGAP PF00620.22 OAJ32489.1 - 2e-38 131.4 0.0 4.6e-38 130.2 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 OAJ32489.1 - 4.3e-16 59.1 0.0 1.1e-14 54.5 0.0 2.9 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 OAJ32489.1 - 4.3e-09 36.3 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif PH_9 PF15410.1 OAJ32489.1 - 0.00046 20.3 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 OAJ32489.1 - 0.015 15.4 0.0 0.49 10.6 0.0 2.4 2 0 0 2 2 2 0 PH domain Tubulin PF00091.20 OAJ32490.1 - 9.4e-73 244.5 0.0 1.7e-72 243.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 OAJ32490.1 - 3.7e-41 140.1 0.0 6.6e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 OAJ32490.1 - 0.00027 20.9 0.0 0.00066 19.7 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 OAJ32490.1 - 0.023 14.1 0.0 0.052 13.0 0.0 1.6 2 0 0 2 2 2 0 Tubulin domain TPR_11 PF13414.1 OAJ32491.1 - 9.1e-07 28.4 3.5 0.0017 17.9 0.0 2.9 3 0 0 3 3 3 2 TPR repeat SHNi-TPR PF10516.4 OAJ32491.1 - 0.00017 20.7 2.5 0.00022 20.3 0.1 2.2 2 0 0 2 2 2 1 SHNi-TPR TPR_2 PF07719.12 OAJ32491.1 - 0.00027 20.6 7.3 0.31 11.0 0.9 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ32491.1 - 0.00069 19.5 3.0 0.068 13.1 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ32491.1 - 0.059 13.0 4.1 5.3 6.8 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ32491.1 - 0.091 12.6 1.3 2.9 7.9 0.0 3.7 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ32491.1 - 0.33 10.8 8.9 1.5 8.7 0.9 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF177 PF02620.12 OAJ32491.1 - 0.79 9.7 4.2 0.25 11.3 0.5 1.9 2 0 0 2 2 2 0 Uncharacterized ACR, COG1399 TPR_14 PF13428.1 OAJ32491.1 - 0.92 10.3 10.5 0.96 10.2 0.5 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Nucleoplasmin PF03066.10 OAJ32491.1 - 1.1 8.8 8.0 2.3 7.7 5.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin PilJ PF13675.1 OAJ32491.1 - 1.1 9.5 5.8 2.8 8.2 0.1 3.6 3 2 1 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term TPR_16 PF13432.1 OAJ32491.1 - 2 9.1 17.6 0.099 13.3 0.6 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat NOA36 PF06524.7 OAJ32491.1 - 3.4 6.8 8.5 5.8 6.0 5.9 1.3 1 0 0 1 1 1 0 NOA36 protein MULE PF10551.4 OAJ32493.1 - 6.7e-10 39.0 0.0 1.3e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ32493.1 - 3.9e-05 22.3 0.0 6.8e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family 4HBT_3 PF13622.1 OAJ32496.1 - 4.4e-29 102.0 2.9 5.7e-29 101.6 2.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily MBOAT PF03062.14 OAJ32497.1 - 3.3e-31 108.5 15.6 3.3e-31 108.5 10.8 3.0 2 2 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family RVT_2 PF07727.9 OAJ32498.1 - 9.3e-86 286.7 0.0 1.3e-85 286.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ32498.1 - 8.6e-20 71.0 0.0 3.3e-19 69.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ32498.1 - 2e-05 24.1 0.3 4.5e-05 22.9 0.2 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF935 PF06074.7 OAJ32498.1 - 1.5 7.4 3.9 2.3 6.8 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) UBN2 PF14223.1 OAJ32499.1 - 4.1e-07 29.7 0.0 7.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAJ32499.1 - 1.5e-05 24.4 0.0 3.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1400 PF07176.6 OAJ32499.1 - 0.014 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) zf-CCHC PF00098.18 OAJ32499.1 - 0.016 15.0 3.9 0.016 15.0 2.7 1.8 2 0 0 2 2 2 0 Zinc knuckle FA_desaturase PF00487.19 OAJ32500.1 - 7.3e-26 91.1 17.5 1.3e-25 90.3 12.2 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 OAJ32500.1 - 1.5e-16 59.3 0.2 2.6e-16 58.5 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Peroxidase_2 PF01328.12 OAJ32501.1 - 2.7e-08 32.8 0.1 5.1e-08 31.9 0.1 1.4 1 1 0 1 1 1 1 Peroxidase, family 2 GTP_EFTU PF00009.22 OAJ32502.1 - 1.2e-16 60.7 0.0 1.8e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LEM PF03020.10 OAJ32503.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 LEM domain zf-C3HC4_2 PF13923.1 OAJ32505.1 - 1.3e-06 28.3 7.8 1.3e-06 28.3 5.4 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ32505.1 - 8.3e-06 25.3 2.2 8.3e-06 25.3 1.6 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ32505.1 - 7.3e-05 22.5 10.2 7.3e-05 22.5 7.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 OAJ32505.1 - 0.00013 21.7 4.4 0.00013 21.7 3.1 3.6 5 0 0 5 5 5 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 OAJ32505.1 - 0.00036 20.1 11.4 0.00036 20.1 7.9 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAJ32505.1 - 0.00078 19.1 1.7 0.00078 19.1 1.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 OAJ32505.1 - 0.0013 18.4 9.0 0.0013 18.4 6.2 2.9 2 1 0 2 2 2 1 zinc-RING finger domain DEAD PF00270.24 OAJ32506.1 - 3.3e-37 127.5 0.1 6.4e-37 126.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ32506.1 - 7e-24 83.4 0.0 3.4e-23 81.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ32506.1 - 2.6e-05 24.1 0.2 6.7e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 OAJ32506.1 - 0.039 13.0 0.0 0.091 11.8 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Hexokinase_2 PF03727.11 OAJ32507.1 - 1.8e-80 269.6 0.0 2.6e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 OAJ32507.1 - 4.2e-66 222.2 0.0 9.1e-66 221.1 0.0 1.5 2 0 0 2 2 2 1 Hexokinase Sigma_reg_N PF13800.1 OAJ32508.1 - 0.052 13.5 0.1 0.052 13.5 0.1 2.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal 7tm_7 PF08395.7 OAJ32508.1 - 9 5.1 18.1 0.067 12.2 6.1 2.1 3 0 0 3 3 3 0 7tm Chemosensory receptor ETF_QO PF05187.8 OAJ32509.1 - 1.8e-22 79.3 0.0 3e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DUF3016 PF11454.3 OAJ32509.1 - 0.032 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) Fer4_21 PF14697.1 OAJ32509.1 - 0.055 13.3 1.1 0.1 12.4 0.8 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 OAJ32509.1 - 0.086 12.7 0.3 0.2 11.6 0.2 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain DPBB_1 PF03330.13 OAJ32510.1 - 1.1e-05 25.3 1.3 0.00014 21.7 0.6 2.8 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ32510.1 - 1.6e-05 24.5 0.3 0.13 11.9 0.1 2.4 2 0 0 2 2 2 2 Barwin family Ank_3 PF13606.1 OAJ32511.1 - 0.0011 18.9 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.25 OAJ32511.1 - 0.0018 17.9 0.4 0.0057 16.4 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 OAJ32511.1 - 0.0044 17.2 0.1 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 OAJ32511.1 - 0.0062 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ32511.1 - 0.0094 16.4 0.1 0.018 15.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) E1-E2_ATPase PF00122.15 OAJ32512.1 - 2.7e-67 226.1 6.6 8.2e-67 224.5 0.3 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 OAJ32512.1 - 9e-23 81.8 0.0 2.3e-22 80.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAJ32512.1 - 2.9e-13 50.3 0.0 5.4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAJ32512.1 - 1.1e-12 47.1 0.0 3.1e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 OAJ32512.1 - 0.00097 18.7 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ32512.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DMA PF03474.9 OAJ32512.1 - 0.029 14.1 0.1 1.9 8.3 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif PsbI PF02532.9 OAJ32512.1 - 0.4 10.3 0.0 0.4 10.3 0.0 3.2 4 0 0 4 4 4 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Kinesin PF00225.18 OAJ32513.1 - 2.8e-103 345.1 0.0 1.6e-102 342.6 0.0 2.2 1 1 0 1 1 1 1 Kinesin motor domain Baculo_PEP_C PF04513.7 OAJ32513.1 - 0.58 9.9 15.2 2.9 7.7 0.1 4.5 3 2 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.4 OAJ32513.1 - 0.67 9.8 7.0 3.6 7.5 0.2 3.9 3 0 0 3 3 3 0 Uncharacterized conserved protein Syntaxin PF00804.20 OAJ32513.1 - 5 7.3 18.7 0.12 12.5 1.7 4.1 3 1 1 4 4 4 0 Syntaxin DUF4126 PF13548.1 OAJ32513.1 - 5.4 6.4 4.2 13 5.1 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) CS PF04969.11 OAJ32514.1 - 1.7e-05 25.3 0.1 3.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 CS domain WD40 PF00400.27 OAJ32515.1 - 1.9e-40 135.3 18.5 2.3e-08 33.6 0.5 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat DUF2415 PF10313.4 OAJ32515.1 - 0.0019 17.8 0.0 0.14 11.8 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) LRR_6 PF13516.1 OAJ32516.1 - 4.6e-20 69.3 0.9 0.46 10.7 0.0 9.0 10 0 0 10 10 9 4 Leucine Rich repeat LRR_4 PF12799.2 OAJ32516.1 - 2.7e-13 49.2 6.8 0.018 14.6 0.4 6.3 3 2 5 8 8 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 OAJ32516.1 - 1.1e-09 36.9 2.1 5.3 7.4 0.0 8.2 7 2 1 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.1 OAJ32516.1 - 2.8e-09 36.5 8.4 0.068 12.9 0.1 6.0 3 2 1 5 5 5 3 Leucine rich repeat LRR_7 PF13504.1 OAJ32516.1 - 1.4e-05 24.4 11.7 13 6.4 0.0 8.2 9 0 0 9 9 8 0 Leucine rich repeat TraH_2 PF06871.6 OAJ32516.1 - 0.039 13.4 0.4 0.057 12.8 0.2 1.3 1 0 0 1 1 1 0 TraH_2 DUF2457 PF10446.4 OAJ32516.1 - 0.08 11.6 20.9 0.11 11.2 14.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TMEM247 PF15444.1 OAJ32516.1 - 0.18 11.5 6.4 0.32 10.7 4.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 CENP-T PF15511.1 OAJ32516.1 - 0.21 10.7 10.9 0.31 10.2 7.6 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Sigma70_ner PF04546.8 OAJ32516.1 - 1.1 8.8 16.0 1.7 8.2 11.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1510 PF07423.6 OAJ32516.1 - 3.8 6.8 11.4 5.7 6.2 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Paf1 PF03985.8 OAJ32516.1 - 6.2 5.4 13.7 8.2 5.0 9.5 1.1 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.9 OAJ32516.1 - 8.6 4.2 12.9 12 3.8 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 OAJ32516.1 - 9.4 4.0 21.5 13 3.5 14.9 1.1 1 0 0 1 1 1 0 Nop14-like family Pex2_Pex12 PF04757.9 OAJ32519.1 - 1.2e-21 77.1 0.4 9.5e-21 74.2 0.3 1.9 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 OAJ32519.1 - 4.4e-07 29.8 1.9 4.8e-07 29.7 0.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ32519.1 - 2.8e-06 26.9 2.1 3.5e-06 26.5 0.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ32519.1 - 0.019 14.7 0.5 0.041 13.7 0.3 1.6 1 0 0 1 1 1 0 Ring finger domain FdhE PF04216.7 OAJ32519.1 - 0.024 14.3 0.2 0.042 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-C3HC4 PF00097.20 OAJ32519.1 - 0.16 11.6 0.7 0.38 10.4 0.2 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAJ32519.1 - 0.43 10.4 2.5 0.84 9.5 1.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING EF-1_beta_acid PF10587.4 OAJ32519.1 - 9 6.5 6.6 33 4.7 0.4 2.5 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Gaa1 PF04114.9 OAJ32521.1 - 3e-45 154.8 6.1 6.6e-21 74.5 0.0 4.1 4 0 0 4 4 4 4 Gaa1-like, GPI transamidase component WD40 PF00400.27 OAJ32522.1 - 2.4e-42 141.3 16.7 4.5e-08 32.6 0.3 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 OAJ32522.1 - 1.9e-10 40.3 0.3 1.9e-10 40.3 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ32522.1 - 0.00012 21.6 0.1 0.00027 20.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.1 OAJ32522.1 - 0.11 12.8 0.4 51 4.3 0.0 4.0 3 0 0 3 3 3 0 PQQ-like domain adh_short_C2 PF13561.1 OAJ32523.1 - 9.2e-28 97.6 0.1 1.1e-27 97.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ32523.1 - 1.2e-26 93.5 1.2 1.6e-26 93.1 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ32523.1 - 1e-10 41.5 0.2 1.6e-10 40.9 0.2 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 OAJ32523.1 - 0.027 13.6 0.0 0.049 12.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 OAJ32523.1 - 0.03 14.7 0.3 0.056 13.8 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 OAJ32523.1 - 0.078 12.7 0.2 0.16 11.6 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TIM-br_sig_trns PF09370.5 OAJ32523.1 - 0.1 11.6 0.8 0.21 10.6 0.2 1.6 2 0 0 2 2 2 0 TIM-barrel signal transduction protein PRTase_2 PF15609.1 OAJ32524.1 - 0.042 13.1 0.1 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Arf PF00025.16 OAJ32526.1 - 1.3e-79 265.4 0.1 1.5e-79 265.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 OAJ32526.1 - 3.6e-14 52.3 0.0 4.4e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 OAJ32526.1 - 2.6e-13 49.7 0.0 2.8e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 OAJ32526.1 - 6e-13 48.2 1.1 1e-09 37.6 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 OAJ32526.1 - 3.1e-11 42.8 0.0 3.6e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 OAJ32526.1 - 3.3e-09 37.2 0.0 4.5e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 OAJ32526.1 - 5.5e-06 26.3 0.0 7.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAJ32526.1 - 0.0053 16.2 0.1 0.042 13.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 OAJ32526.1 - 0.0068 15.4 0.4 0.013 14.5 0.3 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 OAJ32526.1 - 0.077 12.8 0.1 0.14 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain GTP_CH_N PF12471.3 OAJ32527.1 - 2.7e-86 288.1 0.0 4.5e-86 287.4 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 OAJ32527.1 - 6.3e-16 58.0 0.0 1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Sugar_tr PF00083.19 OAJ32528.1 - 8e-27 93.9 8.9 4e-22 78.4 0.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ32528.1 - 1.5e-24 86.3 31.6 4.2e-17 61.8 9.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Peptidase_S10 PF00450.17 OAJ32529.1 - 9.9e-100 334.5 0.0 1.3e-99 334.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 OAJ32529.1 - 0.0012 18.7 0.0 1.8 8.3 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Pyr_redox PF00070.22 OAJ32530.1 - 4.8e-13 49.3 1.0 5.5e-09 36.3 0.5 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ32530.1 - 1e-08 35.3 0.0 0.0061 16.4 0.0 4.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAJ32530.1 - 0.00017 21.6 0.7 0.9 9.5 0.0 3.6 3 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Myosin_N PF02736.14 OAJ32530.1 - 0.12 12.0 0.0 4 7.1 0.1 2.4 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Ctr PF04145.10 OAJ32531.1 - 0.67 9.9 0.0 0.67 9.9 0.0 2.8 3 0 0 3 3 3 0 Ctr copper transporter family MARVEL PF01284.18 OAJ32531.1 - 5.6 6.7 14.1 12 5.6 9.8 1.6 1 0 0 1 1 1 0 Membrane-associating domain Haemolytic PF01809.13 OAJ32532.1 - 0.033 13.7 0.1 0.089 12.4 0.1 1.6 1 0 0 1 1 1 0 Haemolytic domain Nbl1_Borealin_N PF10444.4 OAJ32535.1 - 2.3e-07 30.0 0.7 4e-07 29.3 0.5 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal POX PF07526.6 OAJ32535.1 - 1.7 8.8 4.6 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 Associated with HOX Hydrolase_like PF13242.1 OAJ32537.1 - 1e-19 70.0 0.0 2e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 OAJ32537.1 - 1.1e-17 63.6 0.0 2.3e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase TENA_THI-4 PF03070.11 OAJ32538.1 - 7.1e-15 55.3 0.0 3.6e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 TENA/THI-4/PQQC family FoP_duplication PF13865.1 OAJ32538.1 - 3.9e-06 27.1 0.2 1e-05 25.8 0.2 1.7 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Gar1 PF04410.9 OAJ32539.1 - 2.4e-23 82.2 11.7 4.4e-14 52.2 0.1 3.9 4 0 0 4 4 4 2 Gar1/Naf1 RNA binding region DUF663 PF04950.7 OAJ32541.1 - 9.1e-78 261.2 0.0 1.2e-76 257.5 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 OAJ32541.1 - 7e-21 73.5 0.0 1.3e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain DUF4611 PF15387.1 OAJ32542.1 - 0.036 14.1 1.6 0.11 12.7 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PP_M1 PF03012.9 OAJ32542.1 - 0.1 11.9 1.5 0.17 11.2 1.0 1.3 1 0 0 1 1 1 0 Phosphoprotein SRF-TF PF00319.13 OAJ32543.1 - 2.7e-12 45.7 0.1 4.6e-12 44.9 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Serglycin PF04360.7 OAJ32543.1 - 5.3e-05 22.9 9.3 0.0019 17.9 0.0 3.1 3 0 0 3 3 3 2 Serglycin DUF3099 PF11298.3 OAJ32544.1 - 0.76 9.5 2.3 1.5 8.5 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) WLM PF08325.5 OAJ32545.1 - 0.07 13.0 2.3 0.1 12.4 1.6 1.2 1 0 0 1 1 1 0 WLM domain DUF1183 PF06682.7 OAJ32545.1 - 0.093 12.3 5.3 0.11 12.1 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Pap_E4 PF02711.9 OAJ32545.1 - 0.12 13.2 2.2 0.14 12.9 1.5 1.2 1 0 0 1 1 1 0 E4 protein DUF2360 PF10152.4 OAJ32545.1 - 0.21 11.8 4.8 0.22 11.8 3.3 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) CAP_N PF01213.14 OAJ32545.1 - 0.32 10.2 1.4 0.36 10.0 1.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2201_N PF13203.1 OAJ32545.1 - 0.78 8.8 8.4 1 8.5 5.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain VirionAssem_T7 PF11653.3 OAJ32545.1 - 0.79 10.5 4.5 1.3 9.8 3.1 1.3 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein EMP24_GP25L PF01105.19 OAJ32546.1 - 1.2e-51 174.9 0.0 1.5e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ras PF00071.17 OAJ32547.1 - 1.4e-50 170.7 0.1 1.7e-50 170.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ32547.1 - 6.7e-17 62.0 0.0 1e-16 61.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ32547.1 - 1.3e-11 44.0 0.0 1.7e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ32547.1 - 0.00036 19.7 0.0 0.00043 19.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 OAJ32547.1 - 0.002 16.8 0.8 0.34 9.5 0.1 2.3 2 1 0 2 2 2 2 G-protein alpha subunit RNA_helicase PF00910.17 OAJ32547.1 - 0.018 15.2 0.3 0.61 10.2 0.2 2.2 1 1 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 OAJ32547.1 - 0.084 13.0 0.3 0.19 11.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 OAJ32547.1 - 0.091 12.0 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein SRPRB PF09439.5 OAJ32547.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 OAJ32547.1 - 0.15 11.0 0.4 0.27 10.2 0.1 1.5 2 0 0 2 2 2 0 Septin Thioredoxin PF00085.15 OAJ32548.1 - 4.9e-23 80.7 0.0 6e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 OAJ32548.1 - 7.6e-08 32.5 0.0 1.2e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAJ32548.1 - 8.9e-06 25.7 0.0 0.00031 20.8 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like HyaE PF07449.6 OAJ32548.1 - 0.00058 19.7 0.0 0.00082 19.2 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE KaiB PF07689.7 OAJ32548.1 - 0.00072 18.9 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 KaiB domain Thioredoxin_7 PF13899.1 OAJ32548.1 - 0.00082 19.3 0.0 0.0015 18.5 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 OAJ32548.1 - 0.0011 18.6 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.9 OAJ32548.1 - 0.0029 17.8 0.0 0.0043 17.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_9 PF14595.1 OAJ32548.1 - 0.0034 16.9 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 OAJ32548.1 - 0.0051 16.4 0.0 0.0065 16.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.11 OAJ32548.1 - 0.0057 16.1 0.0 0.0071 15.8 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Redoxin PF08534.5 OAJ32548.1 - 0.0097 15.4 0.0 0.014 14.9 0.0 1.4 1 1 0 1 1 1 1 Redoxin DUF953 PF06110.6 OAJ32548.1 - 0.0098 15.3 0.1 0.042 13.2 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) TraF PF13728.1 OAJ32548.1 - 0.012 15.1 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Glutaredoxin PF00462.19 OAJ32548.1 - 0.018 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin DUF3253 PF11625.3 OAJ32549.1 - 0.011 15.6 0.0 0.039 13.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) RasGAP PF00616.14 OAJ32550.1 - 9.3e-29 100.4 0.0 2.1e-28 99.3 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 OAJ32550.1 - 7.9e-13 48.5 0.0 3.4e-12 46.5 0.0 2.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.1 OAJ32550.1 - 2.1e-06 27.7 0.1 6e-05 22.9 0.0 2.9 2 0 0 2 2 2 1 Cell morphogenesis C-terminal bZIP_1 PF00170.16 OAJ32551.1 - 1.4e-05 24.9 10.7 1.4e-05 24.9 7.4 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 OAJ32551.1 - 0.0013 18.5 8.9 0.0013 18.5 6.2 2.0 2 0 0 2 2 2 1 Basic region leucine zipper Oxysterol_BP PF01237.13 OAJ32553.1 - 1.4e-86 290.1 0.0 2.1e-86 289.6 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Aminotran_1_2 PF00155.16 OAJ32554.1 - 1.1e-33 116.6 0.0 1.3e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAJ32554.1 - 0.063 12.4 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase PAC2 PF09754.4 OAJ32555.1 - 4.2e-25 88.8 0.0 8.3e-25 87.9 0.0 1.5 1 1 0 1 1 1 1 PAC2 family DUF3505 PF12013.3 OAJ32556.1 - 7.4e-05 22.9 3.6 0.00087 19.5 2.4 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3505) bZIP_1 PF00170.16 OAJ32557.1 - 0.00065 19.6 7.5 0.00065 19.6 5.2 2.3 1 1 1 2 2 2 1 bZIP transcription factor CD20 PF04103.10 OAJ32557.1 - 0.18 11.7 0.5 0.3 10.9 0.4 1.2 1 0 0 1 1 1 0 CD20-like family Ndc1_Nup PF09531.5 OAJ32557.1 - 4.3 5.6 5.4 3.2 6.0 2.6 1.4 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Complex1_LYR_2 PF13233.1 OAJ32557.1 - 6.1 7.3 13.1 0.12 12.9 2.5 2.2 2 0 0 2 2 2 0 Complex1_LYR-like Macoilin PF09726.4 OAJ32557.1 - 6.1 5.0 16.4 1.1 7.5 1.7 2.0 2 0 0 2 2 2 0 Transmembrane protein Zip PF02535.17 OAJ32557.1 - 8 5.3 9.6 15 4.4 6.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter MFS_1 PF07690.11 OAJ32558.1 - 4.8e-27 94.6 29.9 9.2e-27 93.6 20.7 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily MutS_V PF00488.16 OAJ32559.1 - 2.4e-70 236.6 0.0 5.4e-69 232.1 0.0 2.4 1 1 1 2 2 2 1 MutS domain V MutS_III PF05192.13 OAJ32559.1 - 4.2e-44 150.7 0.0 1.6e-43 148.8 0.0 2.0 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.15 OAJ32559.1 - 3.3e-19 68.9 0.0 7.3e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 OAJ32559.1 - 1.5e-08 34.7 1.2 5.1e-08 33.0 0.0 2.6 3 0 0 3 3 3 1 MutS domain II AAA_23 PF13476.1 OAJ32559.1 - 0.34 11.2 3.0 2 8.6 0.0 2.7 2 1 1 3 3 3 0 AAA domain NIR_SIR PF01077.17 OAJ32560.1 - 3.2e-29 101.3 0.0 6.1e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 OAJ32560.1 - 2.1e-25 89.8 0.2 5.2e-25 88.5 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ32560.1 - 1.1e-16 61.0 6.7 1.6e-13 50.8 0.5 3.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 OAJ32560.1 - 3.6e-16 58.7 0.0 1.1e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.10 OAJ32560.1 - 2.2e-13 50.0 2.9 4e-11 42.7 3.1 2.6 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.12 OAJ32560.1 - 7.3e-13 47.9 0.0 1.5e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.21 OAJ32560.1 - 4.4e-11 42.2 0.0 1.6e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 OAJ32560.1 - 1e-07 32.2 1.1 0.0028 17.7 0.1 4.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ32560.1 - 0.00017 20.5 3.6 0.025 13.4 0.1 4.2 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ32560.1 - 0.0003 19.7 4.6 0.08 11.7 0.1 3.2 1 1 1 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 OAJ32560.1 - 0.00097 18.9 3.2 5 6.8 0.0 3.7 3 1 1 4 4 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 OAJ32560.1 - 0.0029 16.5 0.0 0.73 8.6 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 OAJ32560.1 - 0.012 15.8 1.7 2.7 8.3 0.0 3.1 3 0 0 3 3 3 0 Putative NAD(P)-binding TrkA_N PF02254.13 OAJ32560.1 - 0.018 15.0 1.9 1.6 8.7 0.2 2.9 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.15 OAJ32560.1 - 0.035 14.2 1.1 4.6 7.3 0.0 3.6 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Oxidored_molyb PF00174.14 OAJ32561.1 - 1.8e-48 164.1 0.0 3.1e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 OAJ32561.1 - 9.7e-42 141.7 0.1 1.8e-41 140.8 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.19 OAJ32561.1 - 1.2e-23 83.0 0.0 4.4e-23 81.2 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 OAJ32561.1 - 4.2e-21 75.5 0.0 2e-20 73.3 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 OAJ32561.1 - 4.4e-20 71.2 0.0 7.8e-20 70.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 OAJ32561.1 - 0.00037 20.4 0.0 0.0064 16.3 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Voltage_CLC PF00654.15 OAJ32562.1 - 8.2e-92 307.9 29.6 1.5e-91 307.0 20.5 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 OAJ32562.1 - 9.4e-13 47.7 0.1 2.3e-06 27.2 0.1 2.6 2 0 0 2 2 2 2 CBS domain Nic96 PF04097.9 OAJ32563.1 - 1.1e-164 548.9 0.0 1.4e-164 548.6 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 DUF3013 PF11217.3 OAJ32564.1 - 0.12 12.0 0.9 0.19 11.4 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3013) NESP55 PF06390.7 OAJ32564.1 - 0.45 9.8 1.7 0.57 9.5 1.1 1.1 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Abhydrolase_5 PF12695.2 OAJ32565.1 - 3.2e-05 23.7 0.1 8.1e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAJ32565.1 - 0.00032 20.3 0.0 0.001 18.7 0.0 1.8 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 OAJ32565.1 - 0.0019 17.5 0.0 0.0038 16.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 OAJ32565.1 - 0.0023 16.9 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 OAJ32565.1 - 0.046 13.2 0.0 0.19 11.2 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold RRS1 PF04939.7 OAJ32566.1 - 4.1e-53 179.2 0.7 4.9e-53 178.9 0.5 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Peptidase_S24 PF00717.18 OAJ32567.1 - 5.4e-09 35.5 0.0 1.1e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase S24-like zf-RING_UBOX PF13445.1 OAJ32569.1 - 0.00063 19.4 0.2 0.0018 17.9 0.1 1.9 1 1 0 1 1 1 1 RING-type zinc-finger SPRR2 PF14820.1 OAJ32569.1 - 5 7.0 15.2 1.2 9.0 5.4 2.2 2 0 0 2 2 2 0 Small proline-rich 2 Aminotran_1_2 PF00155.16 OAJ32570.1 - 1.7e-90 303.6 0.0 1.9e-90 303.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Complex1_51K PF01512.12 OAJ32571.1 - 2.6e-48 163.5 0.0 4.5e-48 162.8 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 OAJ32571.1 - 1e-20 72.6 0.4 2.2e-20 71.5 0.3 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 OAJ32571.1 - 1.6e-07 31.0 0.0 3.6e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 SLBB domain Peptidase_C14 PF00656.17 OAJ32572.1 - 1.8e-64 217.8 0.0 2.2e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DXP_synthase_N PF13292.1 OAJ32572.1 - 0.12 11.2 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Aminotran_1_2 PF00155.16 OAJ32573.1 - 2.9e-70 237.0 0.0 3.8e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 OAJ32573.1 - 2.7e-05 23.0 0.0 4.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 OAJ32573.1 - 0.0013 17.1 0.0 0.003 15.9 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 OAJ32573.1 - 0.015 14.4 0.1 0.026 13.6 0.1 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Arf PF00025.16 OAJ32575.1 - 1.6e-64 216.3 0.0 1.7e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 OAJ32575.1 - 6.8e-09 35.1 0.0 8.9e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 OAJ32575.1 - 2.2e-08 33.2 0.1 4.2e-05 22.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 OAJ32575.1 - 4.5e-08 32.6 0.0 5.6e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ32575.1 - 1.1e-07 32.3 0.0 1.6e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 OAJ32575.1 - 2.2e-06 27.5 0.0 3.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 OAJ32575.1 - 1.9e-05 23.9 0.0 2.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 OAJ32575.1 - 0.0055 16.1 0.0 0.17 11.2 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 OAJ32575.1 - 0.019 14.4 0.0 0.046 13.2 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CENP-M PF11111.3 OAJ32575.1 - 0.049 12.8 0.0 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 Centromere protein M (CENP-M) cobW PF02492.14 OAJ32575.1 - 0.079 12.3 0.0 4.7 6.6 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KOW PF00467.24 OAJ32576.1 - 7.7e-09 34.9 1.6 1.7e-08 33.8 1.1 1.6 1 0 0 1 1 1 1 KOW motif SIR2 PF02146.12 OAJ32577.1 - 2.3e-51 174.0 0.0 1.5e-50 171.4 0.0 2.2 2 1 0 2 2 2 1 Sir2 family DUF592 PF04574.8 OAJ32577.1 - 1.8e-08 34.0 0.3 2.4e-07 30.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF592) WD40 PF00400.27 OAJ32578.1 - 1.8e-16 59.2 9.0 1.8e-06 27.6 0.1 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat DLIC PF05783.6 OAJ32578.1 - 0.91 8.1 3.6 1.9 7.0 2.5 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF2937 PF11157.3 OAJ32579.1 - 0.92 8.8 10.3 5.7 6.2 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Glt_symporter PF03616.9 OAJ32579.1 - 1.5 7.1 0.1 3.4 6.0 0.1 1.4 1 0 0 1 1 1 0 Sodium/glutamate symporter Nuf2 PF03800.9 OAJ32580.1 - 1.7e-31 109.1 1.9 1.8e-31 109.0 0.0 2.0 2 1 0 2 2 2 1 Nuf2 family Reo_sigmaC PF04582.7 OAJ32580.1 - 0.13 11.4 3.3 0.33 10.0 0.2 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Atg14 PF10186.4 OAJ32580.1 - 0.64 8.9 35.5 0.22 10.4 10.8 2.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MscS_porin PF12795.2 OAJ32580.1 - 2.4 7.4 33.0 2.9 7.1 10.2 2.7 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF2935 PF11155.3 OAJ32580.1 - 3.2 7.8 14.1 0.4 10.7 0.6 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) GAS PF13851.1 OAJ32580.1 - 7.2 5.7 38.0 13 4.9 16.1 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 OAJ32580.1 - 8.7 5.8 39.4 0.13 11.7 11.1 3.0 1 1 2 3 3 3 0 IncA protein RNA_lig_T4_1 PF09511.5 OAJ32581.1 - 5.2e-79 264.7 0.0 9.1e-79 263.9 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 OAJ32581.1 - 1.4e-23 83.6 0.2 1.8e-14 53.9 0.0 2.4 1 1 1 2 2 2 2 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 OAJ32581.1 - 3.7e-18 65.6 0.0 1.5e-17 63.6 0.0 2.0 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain KTI12 PF08433.5 OAJ32581.1 - 0.02 14.1 0.2 1.1 8.4 0.2 2.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 OAJ32581.1 - 0.055 13.3 0.0 0.2 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 OAJ32582.1 - 2.7e-59 195.0 25.3 2.5e-09 36.6 0.0 9.4 8 1 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 OAJ32582.1 - 8e-12 44.7 0.1 1.5e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ32582.1 - 8.5e-10 38.0 0.1 1.7e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 OAJ32582.1 - 6.8e-07 27.7 22.9 0.058 11.5 0.3 6.9 4 2 3 7 7 7 6 Nucleoporin Nup120/160 Pkinase PF00069.20 OAJ32584.1 - 3.3e-39 134.6 0.0 4.2e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ32584.1 - 5.7e-16 58.3 0.0 8.4e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ32584.1 - 1.5e-06 28.1 0.1 0.003 17.3 0.0 3.3 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 OAJ32584.1 - 0.022 13.5 0.1 0.032 13.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF2404 PF10296.4 OAJ32585.1 - 1.3e-28 98.8 0.1 2.5e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Pescadillo_N PF06732.6 OAJ32586.1 - 8.6e-116 386.0 1.2 9.6e-116 385.9 0.0 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 OAJ32586.1 - 5e-10 39.3 0.0 1.1e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Mucin PF01456.12 OAJ32587.1 - 0.0018 18.0 17.2 0.021 14.5 5.9 2.5 2 1 0 2 2 2 2 Mucin-like glycoprotein Pkinase PF00069.20 OAJ32588.1 - 4e-66 222.8 0.0 5e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ32588.1 - 5.8e-29 100.9 0.0 7.9e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 OAJ32588.1 - 6.9e-13 48.8 0.6 6.9e-13 48.8 0.4 2.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 OAJ32588.1 - 7.1e-09 35.0 0.0 1.4e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 OAJ32588.1 - 1.3e-05 24.9 0.2 0.076 12.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain APH PF01636.18 OAJ32588.1 - 0.039 13.6 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fibrinogen_BP PF08017.6 OAJ32589.1 - 0.03 12.5 1.2 0.061 11.5 0.9 1.4 1 0 0 1 1 1 0 Fibrinogen binding protein zf-Di19 PF05605.7 OAJ32589.1 - 0.17 12.0 0.1 0.43 10.7 0.1 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Ish1 PF10281.4 OAJ32590.1 - 2.9e-47 158.3 24.1 4.1e-11 42.7 0.2 6.5 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein SAP PF02037.22 OAJ32590.1 - 0.003 17.0 0.0 2.5 7.6 0.0 4.0 4 0 0 4 4 4 1 SAP domain LEM PF03020.10 OAJ32590.1 - 0.028 13.8 0.0 1.7 8.1 0.0 3.2 4 0 0 4 4 4 0 LEM domain HeH PF12949.2 OAJ32590.1 - 0.13 11.8 3.9 3.7 7.1 0.0 4.4 6 0 0 6 6 6 0 HeH/LEM domain RRM_1 PF00076.17 OAJ32591.1 - 3.4e-18 65.0 0.1 3.3e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ32591.1 - 1.4e-12 47.2 0.0 2.8e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ32591.1 - 5.4e-12 45.5 0.0 2.6e-06 27.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 OAJ32591.1 - 0.03 14.0 0.4 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 Ferritin_2 PF13668.1 OAJ32592.1 - 2e-47 160.5 4.3 3.1e-47 159.9 3.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain RNA_pol_Rpb2_6 PF00562.23 OAJ32593.1 - 1.7e-122 408.9 0.2 2.3e-117 392.0 0.1 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 OAJ32593.1 - 2.3e-65 219.3 0.2 3.6e-65 218.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 OAJ32593.1 - 2.1e-47 161.0 0.0 4e-47 160.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 OAJ32593.1 - 4e-28 97.4 0.1 1e-27 96.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 OAJ32593.1 - 7.4e-25 86.5 0.1 2.2e-24 85.0 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 OAJ32593.1 - 6.8e-24 83.4 0.1 1.7e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 OAJ32593.1 - 6.3e-19 67.6 0.1 1.3e-18 66.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 CWC25 PF12542.3 OAJ32594.1 - 3e-25 88.5 1.0 3e-25 88.5 0.7 3.6 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 OAJ32594.1 - 2.1e-13 50.0 12.2 2.1e-13 50.0 8.5 3.7 3 1 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF3635 PF12330.3 OAJ32595.1 - 1.3e-13 50.8 0.0 2.6e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) FG-GAP_2 PF14312.1 OAJ32595.1 - 0.018 15.0 0.0 0.047 13.7 0.0 1.7 1 0 0 1 1 1 0 FG-GAP repeat Nucleoplasmin PF03066.10 OAJ32595.1 - 0.026 14.0 5.2 0.061 12.8 3.6 1.6 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 OAJ32595.1 - 0.59 9.9 6.3 2.2 8.0 4.4 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 OAJ32595.1 - 8.9 5.4 8.8 20 4.3 6.1 1.5 1 0 0 1 1 1 0 NOA36 protein Ribosomal_L1 PF00687.16 OAJ32596.1 - 1.4e-23 83.4 0.0 3.8e-22 78.7 0.0 2.0 2 0 0 2 2 2 2 Ribosomal protein L1p/L10e family NARP1 PF12569.3 OAJ32597.1 - 1.6e-163 545.2 9.9 2.8e-162 541.0 6.9 2.2 1 1 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_7 PF13176.1 OAJ32597.1 - 2.5e-13 48.7 4.5 0.0056 16.3 0.0 7.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ32597.1 - 5.5e-12 45.1 32.6 0.0099 16.4 0.1 10.7 11 1 1 12 12 10 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ32597.1 - 5.9e-12 44.5 26.4 1.7e-05 24.3 0.0 10.1 11 1 0 11 11 11 3 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ32597.1 - 1.1e-11 43.7 3.0 3.5e-05 23.1 0.0 6.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ32597.1 - 1.4e-11 43.8 19.2 1.1e-05 24.9 0.1 7.3 6 2 0 7 7 6 2 TPR repeat TPR_19 PF14559.1 OAJ32597.1 - 5.4e-09 36.2 32.0 0.031 14.6 0.0 8.8 7 2 2 9 9 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ32597.1 - 1.7e-08 34.2 23.1 0.0057 16.5 0.1 7.1 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ32597.1 - 1.2e-06 28.2 6.4 0.0061 16.3 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ32597.1 - 4e-06 26.6 1.9 1.9 8.8 0.0 7.6 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ32597.1 - 7.5e-05 23.2 63.4 0.26 12.0 0.1 11.1 10 3 4 14 14 11 6 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ32597.1 - 0.006 16.9 16.8 0.02 15.3 0.1 7.0 7 1 0 7 7 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ32597.1 - 0.026 14.3 11.3 0.11 12.3 0.0 5.0 7 0 0 7 7 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 OAJ32597.1 - 0.046 13.6 0.6 29 4.6 0.0 4.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat AMP-binding PF00501.23 OAJ32598.1 - 2.8e-92 309.2 0.0 3.6e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ32598.1 - 3.2e-08 34.4 0.2 1.1e-07 32.7 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Amino_oxidase PF01593.19 OAJ32599.1 - 2.9e-47 161.7 0.3 2.2e-46 158.9 0.2 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAJ32599.1 - 2.4e-10 40.2 0.2 5.3e-10 39.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 OAJ32599.1 - 1.4e-06 27.0 0.5 0.0023 16.4 0.2 2.3 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.19 OAJ32599.1 - 4.3e-06 25.8 0.4 0.00098 18.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAJ32599.1 - 7.9e-05 22.9 0.2 0.00075 19.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAJ32599.1 - 0.00017 20.5 0.2 0.00026 19.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 OAJ32599.1 - 0.00022 21.3 0.1 0.037 14.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAJ32599.1 - 0.00025 20.2 0.2 0.00043 19.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 OAJ32599.1 - 0.00066 18.8 0.4 0.0012 17.9 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 OAJ32599.1 - 0.0017 18.3 0.3 0.0055 16.6 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ32599.1 - 0.0024 17.6 0.2 1.9 8.2 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 OAJ32599.1 - 0.017 14.0 0.1 3.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.2 OAJ32599.1 - 0.094 11.7 0.7 0.16 11.0 0.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 OAJ32599.1 - 0.12 11.2 0.8 2.1 7.1 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Period_C PF12114.3 OAJ32600.1 - 0.37 10.3 5.9 0.12 11.9 1.5 1.9 1 1 0 2 2 2 0 Period protein 2/3C-terminal region GLTSCR1 PF15249.1 OAJ32600.1 - 3.1 7.9 5.7 0.31 11.1 0.2 2.0 2 1 0 2 2 2 0 Glioma tumor suppressor candidate region EspF PF04806.7 OAJ32602.1 - 0.096 12.8 6.7 0.27 11.4 3.2 2.8 2 0 0 2 2 2 0 EspF protein repeat PMP1_2 PF08114.6 OAJ32603.1 - 0.039 13.4 0.4 0.071 12.6 0.3 1.3 1 0 0 1 1 1 0 ATPase proteolipid family Podoplanin PF05808.6 OAJ32603.1 - 0.15 11.5 22.5 0.88 9.1 15.6 2.2 1 1 0 1 1 1 0 Podoplanin Adeno_E3_CR2 PF02439.10 OAJ32603.1 - 0.3 10.6 3.5 0.55 9.8 2.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 OAD_gamma PF04277.8 OAJ32603.1 - 4.1 7.8 0.0 4.1 7.8 0.0 3.0 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain TFIIA PF03153.8 OAJ32603.1 - 7.9 6.2 27.2 1.2 9.0 2.6 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Abhydrolase_5 PF12695.2 OAJ32604.1 - 0.00013 21.7 0.0 0.0055 16.4 0.0 2.5 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ32604.1 - 0.00067 19.5 0.1 0.45 10.3 0.0 2.5 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ32604.1 - 0.025 14.1 0.1 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAJ32604.1 - 0.07 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pirin PF02678.11 OAJ32605.1 - 5.1e-29 100.2 0.0 9.2e-29 99.4 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 OAJ32605.1 - 1.1e-23 83.2 0.0 2.7e-23 82.0 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 OAJ32605.1 - 0.0082 15.6 0.6 0.039 13.4 0.5 2.0 2 0 0 2 2 2 1 Cupin domain Pro_isomerase PF00160.16 OAJ32606.1 - 4.7e-29 101.5 0.0 7.4e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 OAJ32606.1 - 1e-13 50.7 0.0 1.7e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ32606.1 - 1e-10 41.3 0.0 2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ32606.1 - 9.8e-07 28.5 0.1 1.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_5 PF12695.2 OAJ32607.1 - 4.9e-05 23.1 0.1 0.00014 21.6 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 OAJ32607.1 - 0.0038 16.8 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) CTP_transf_2 PF01467.21 OAJ32608.1 - 1.1e-30 106.7 0.0 1.5e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase MIP PF00230.15 OAJ32609.1 - 2e-40 138.6 14.5 2.7e-40 138.2 10.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Cucumo_2B PF03263.8 OAJ32609.1 - 0.0081 16.4 5.0 0.015 15.5 3.4 1.4 1 0 0 1 1 1 1 Cucumovirus protein 2B DUF159 PF02586.9 OAJ32610.1 - 1e-47 162.3 0.0 2.2e-47 161.3 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, COG2135 DUF1669 PF07894.7 OAJ32610.1 - 0.19 10.8 2.0 0.32 10.1 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) Amastin PF07344.6 OAJ32611.1 - 0.7 9.5 9.9 0.29 10.7 4.2 2.0 2 0 0 2 2 2 0 Amastin surface glycoprotein PMP22_Claudin PF00822.15 OAJ32611.1 - 4.8 6.8 9.6 0.27 10.8 2.4 1.9 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Nol1_Nop2_Fmu PF01189.12 OAJ32612.1 - 4.8e-16 58.9 0.1 2.6e-10 40.1 0.0 2.7 2 1 0 2 2 2 2 NOL1/NOP2/sun family HWE_HK PF07536.9 OAJ32612.1 - 0.043 14.2 0.3 0.043 14.2 0.2 2.4 3 0 0 3 3 3 0 HWE histidine kinase Sas10_Utp3 PF04000.10 OAJ32613.1 - 4.4e-10 39.6 0.2 9.9e-10 38.4 0.1 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF4444 PF14563.1 OAJ32613.1 - 4 6.8 5.9 26 4.3 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4444) CDC45 PF02724.9 OAJ32613.1 - 7.3 4.4 7.9 9.3 4.1 5.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1900 PF08954.6 OAJ32614.1 - 6.8e-46 155.1 0.0 1.3e-21 76.5 0.0 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF1900) WD40 PF00400.27 OAJ32614.1 - 0.00019 21.1 6.3 0.11 12.3 0.1 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat MFS_1 PF07690.11 OAJ32615.1 - 8.8e-28 97.0 44.0 1.5e-26 92.9 26.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Myc_target_1 PF15179.1 OAJ32615.1 - 0.034 13.7 0.0 0.095 12.2 0.0 1.7 1 0 0 1 1 1 0 Myc target protein 1 DUF1049 PF06305.6 OAJ32615.1 - 0.14 11.6 0.1 0.14 11.6 0.1 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF1049) Plus-3 PF03126.13 OAJ32616.1 - 2e-09 37.4 0.0 3.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain ECSIT PF06239.6 OAJ32616.1 - 0.077 11.8 0.1 0.17 10.7 0.1 1.5 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway DLH PF01738.13 OAJ32617.1 - 4.7e-14 52.1 0.5 6.3e-14 51.7 0.4 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 OAJ32617.1 - 0.00019 21.1 0.1 0.00027 20.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Nup35_RRM PF05172.8 OAJ32618.1 - 2.7e-06 27.0 0.0 6.5e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 OAJ32618.1 - 5.2e-05 22.9 0.0 9.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 OAJ32619.1 - 1e-08 35.0 0.0 0.0016 18.3 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ32619.1 - 1.9e-08 33.8 1.1 0.0063 16.1 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1824 PF08854.5 OAJ32619.1 - 0.033 13.7 0.1 0.088 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) DUF4448 PF14610.1 OAJ32620.1 - 1.6e-07 30.9 0.0 2.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) IKI3 PF04762.7 OAJ32621.1 - 5.2e-235 782.4 0.0 6.3e-235 782.1 0.0 1.1 1 0 0 1 1 1 1 IKI3 family Se-cys_synth_N PF12390.3 OAJ32621.1 - 0.0084 16.1 0.9 0.0084 16.1 0.6 2.4 2 0 0 2 2 2 1 Selenocysteine synthase N terminal DUF342 PF03961.8 OAJ32621.1 - 0.3 9.4 0.1 0.55 8.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Peptidase_M24 PF00557.19 OAJ32622.1 - 1.2e-43 149.0 0.1 1.7e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3663 PF12404.3 OAJ32622.1 - 0.026 14.2 0.3 4.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Peptidase PCI PF01399.22 OAJ32623.1 - 1.2e-10 41.5 0.2 4.3e-10 39.8 0.1 2.0 1 0 0 1 1 1 1 PCI domain Peptidase_M15_2 PF05951.8 OAJ32623.1 - 0.15 11.5 6.6 0.68 9.3 0.0 3.6 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF882) DUF829 PF05705.9 OAJ32624.1 - 8.7e-25 87.7 0.1 2.4e-15 56.9 0.0 3.4 3 1 0 3 3 3 3 Eukaryotic protein of unknown function (DUF829) Avl9 PF09794.4 OAJ32625.1 - 1.1e-122 409.1 0.0 1.4e-122 408.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 OAJ32625.1 - 1.3e-06 27.8 0.0 0.04 13.1 0.0 2.9 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 OAJ32625.1 - 3.9e-06 26.5 0.0 0.0029 17.2 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis Afi1 PF07792.7 OAJ32625.1 - 0.0033 17.4 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Hepar_II_III PF07940.8 OAJ32626.1 - 1.7e-05 24.7 1.8 6.6e-05 22.7 1.3 2.1 1 1 0 1 1 1 1 Heparinase II/III-like protein Ribosomal_S2 PF00318.15 OAJ32627.1 - 4.2e-46 156.8 0.0 5e-24 84.6 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Gloverin PF10793.4 OAJ32627.1 - 1.9 8.0 4.5 2.7 7.6 1.6 2.1 2 1 0 2 2 2 0 Gloverin-like protein Pkinase PF00069.20 OAJ32628.1 - 1.6e-26 92.9 0.0 1.4e-23 83.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ32628.1 - 6.3e-13 48.3 0.0 7.1e-10 38.3 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase ECH PF00378.15 OAJ32629.1 - 1.2e-75 253.8 3.0 1.5e-75 253.5 2.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 OAJ32629.1 - 0.0002 21.1 1.9 0.0021 17.8 0.0 2.3 2 0 0 2 2 2 1 Peptidase family S49 ECH_C PF13766.1 OAJ32629.1 - 0.11 12.6 0.3 0.24 11.5 0.2 1.5 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region SDH_sah PF01972.11 OAJ32629.1 - 0.12 11.1 0.1 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Porphobil_deam PF01379.15 OAJ32630.1 - 1.5e-67 226.6 0.0 3.6e-63 212.3 0.0 2.5 3 0 0 3 3 3 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 OAJ32630.1 - 1e-12 47.9 0.0 6.7e-08 32.5 0.0 2.7 2 0 0 2 2 2 2 Porphobilinogen deaminase, C-terminal domain Profilin PF00235.14 OAJ32630.1 - 0.21 11.6 0.0 0.48 10.5 0.0 1.5 1 0 0 1 1 1 0 Profilin DAHP_synth_1 PF00793.15 OAJ32631.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 DAHP synthetase I family Med3 PF11593.3 OAJ32631.1 - 0.16 11.1 7.4 0.23 10.6 5.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MIP PF00230.15 OAJ32632.1 - 3.5e-48 164.0 5.9 4.9e-48 163.5 4.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF3925 PF13063.1 OAJ32632.1 - 2.3 8.3 6.7 0.35 10.9 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3925) GTP_EFTU PF00009.22 OAJ32633.1 - 5.5e-45 153.1 0.0 7.4e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 OAJ32633.1 - 2.5e-09 37.2 0.1 6.8e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 OAJ32633.1 - 3.5e-07 30.1 0.0 8.6e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 OAJ32633.1 - 6.3e-07 29.4 0.3 1.7e-06 28.0 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 OAJ32633.1 - 1.6e-06 27.6 0.3 3.7e-06 26.4 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SRPRB PF09439.5 OAJ32633.1 - 0.0007 18.8 0.0 0.59 9.3 0.0 2.2 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Miro PF08477.8 OAJ32633.1 - 0.0076 16.7 0.0 0.042 14.3 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein Septin PF00735.13 OAJ32633.1 - 0.023 13.7 0.0 0.081 11.9 0.0 1.8 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.18 OAJ32633.1 - 0.033 14.0 0.0 0.69 9.7 0.0 2.3 1 1 1 2 2 2 0 Dynamin family cobW PF02492.14 OAJ32633.1 - 0.04 13.3 0.0 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 OAJ32633.1 - 0.049 13.3 0.1 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 OAJ32633.1 - 0.067 12.4 0.0 4 6.6 0.0 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B HBS1_N PF08938.5 OAJ32634.1 - 2.3e-09 37.2 0.9 5.6e-09 35.9 0.6 1.6 1 0 0 1 1 1 1 HBS1 N-terminus DUF572 PF04502.8 OAJ32634.1 - 0.058 12.6 5.5 0.08 12.1 3.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Rhodanese PF00581.15 OAJ32635.1 - 3.5e-16 59.5 0.0 6.8e-09 36.0 0.0 3.2 2 1 0 2 2 2 2 Rhodanese-like domain RNA_pol_Rbc25 PF08292.7 OAJ32636.1 - 1.9e-28 99.0 0.0 1.9e-27 95.8 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 OAJ32636.1 - 5.7e-16 58.3 0.0 1.2e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 OAJ32636.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.8 1 1 0 1 1 1 0 S1 RNA binding domain Fip1 PF05182.8 OAJ32638.1 - 8e-19 66.6 0.7 1.4e-18 65.8 0.5 1.4 1 0 0 1 1 1 1 Fip1 motif DUF1777 PF08648.7 OAJ32638.1 - 0.0022 17.7 5.5 0.0022 17.7 3.8 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF1777) COPI_C PF06957.6 OAJ32638.1 - 2.2 6.7 11.0 5.8 5.3 7.6 1.6 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Lipase_GDSL PF00657.17 OAJ32639.1 - 5.7e-15 55.7 0.0 7.3e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 OAJ32639.1 - 2.9e-06 27.5 0.1 4.7e-06 26.8 0.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF3385 PF11865.3 OAJ32640.1 - 1.5e-46 158.2 0.0 7.2e-44 149.5 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) HEAT_2 PF13646.1 OAJ32640.1 - 1.1e-19 70.4 19.9 0.00028 21.0 0.0 9.9 5 3 4 9 9 9 4 HEAT repeats HEAT PF02985.17 OAJ32640.1 - 1.9e-12 46.1 19.6 0.64 10.2 0.1 11.8 12 0 0 12 12 11 4 HEAT repeat Cnd1 PF12717.2 OAJ32640.1 - 9.1e-07 28.8 2.3 0.003 17.4 0.0 5.9 5 1 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 OAJ32640.1 - 2.2e-05 24.4 4.3 0.57 10.0 0.0 5.6 4 1 1 6 6 6 1 Parkin co-regulated protein FAT PF02259.18 OAJ32640.1 - 3.2e-05 23.1 2.1 7.8e-05 21.8 0.2 2.5 2 0 0 2 2 2 1 FAT domain HEAT_EZ PF13513.1 OAJ32640.1 - 0.00012 22.3 44.8 0.15 12.6 0.3 13.3 10 3 7 18 18 16 3 HEAT-like repeat UME PF08064.8 OAJ32640.1 - 0.00012 21.9 0.7 3 7.8 0.0 5.0 4 1 1 5 5 5 2 UME (NUC010) domain IBN_N PF03810.14 OAJ32640.1 - 0.0025 17.7 1.4 1.4 8.9 0.0 5.0 5 1 0 5 5 5 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 OAJ32640.1 - 0.0026 16.1 9.0 0.031 12.5 0.1 5.2 4 2 1 5 5 5 1 Adaptin N terminal region Proteasom_PSMB PF10508.4 OAJ32640.1 - 0.0029 15.9 0.1 0.043 12.0 0.1 2.6 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit FdhE PF04216.7 OAJ32640.1 - 0.014 15.1 5.2 0.2 11.3 0.1 3.7 4 0 0 4 4 4 0 Protein involved in formate dehydrogenase formation RIX1 PF08167.7 OAJ32640.1 - 0.015 14.9 3.5 27 4.3 0.0 5.9 6 1 1 7 7 7 0 rRNA processing/ribosome biogenesis TPR_11 PF13414.1 OAJ32640.1 - 0.018 14.7 0.8 0.74 9.5 0.0 3.5 3 0 0 3 3 3 0 TPR repeat VHS PF00790.14 OAJ32640.1 - 0.02 14.5 0.4 15 5.1 0.0 3.9 4 1 1 5 5 5 0 VHS domain Sec7_N PF12783.2 OAJ32640.1 - 1.1 8.6 7.5 11 5.4 0.0 3.9 5 0 0 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal GPP34 PF05719.6 OAJ32641.1 - 7.2e-62 209.1 0.0 1.2e-61 208.3 0.0 1.4 1 1 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Peptidase_M24 PF00557.19 OAJ32642.1 - 2.3e-20 73.0 0.0 3e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_S19e PF01090.14 OAJ32644.1 - 2.6e-52 175.9 0.0 3e-52 175.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Bd3614_N PF14442.1 OAJ32644.1 - 0.11 12.4 6.0 0.17 11.8 4.1 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal RXT2_N PF08595.6 OAJ32644.1 - 0.16 11.7 4.4 0.18 11.5 3.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.7 OAJ32644.1 - 0.28 10.4 8.2 0.34 10.1 5.7 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.7 OAJ32644.1 - 0.45 10.1 9.2 0.49 10.0 6.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.3 OAJ32644.1 - 0.67 9.8 12.3 0.75 9.6 8.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.8 OAJ32644.1 - 1.8 8.3 9.2 1.9 8.3 6.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.7 OAJ32644.1 - 2.6 7.2 9.7 2.9 7.0 6.7 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 OAJ32644.1 - 3 5.7 7.3 3.5 5.5 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 OAJ32644.1 - 6.9 6.2 14.9 9.5 5.7 10.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 OAJ32644.1 - 10 3.9 11.9 11 3.8 8.3 1.0 1 0 0 1 1 1 0 Nop14-like family TFCD_C PF12612.3 OAJ32645.1 - 2.9e-29 101.8 0.0 2.4e-28 98.8 0.0 2.7 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal Cnd1 PF12717.2 OAJ32645.1 - 0.0039 17.0 0.2 0.91 9.3 0.0 3.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 OAJ32645.1 - 0.0041 17.0 0.0 0.0041 17.0 0.0 7.1 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.1 OAJ32645.1 - 0.011 16.2 0.1 0.011 16.2 0.0 7.5 8 1 1 9 9 9 0 HEAT-like repeat B56 PF01603.15 OAJ32645.1 - 0.019 13.5 0.1 0.26 9.8 0.0 2.3 2 0 0 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) Vac14_Fab1_bd PF12755.2 OAJ32645.1 - 0.021 15.2 0.1 0.23 11.8 0.0 2.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Nefa_Nip30_N PF10187.4 OAJ32646.1 - 8.5e-26 90.1 7.9 1.4e-25 89.4 5.5 1.4 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 zf-C4H2 PF10146.4 OAJ32646.1 - 0.087 12.8 1.2 0.14 12.1 0.8 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Ribosomal_S7 PF00177.16 OAJ32647.1 - 2.2e-28 98.6 0.0 5.2e-28 97.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e Med3 PF11593.3 OAJ32647.1 - 3.6 6.7 8.5 5.4 6.1 5.9 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HLH PF00010.21 OAJ32648.1 - 8.3e-15 54.2 0.2 1.5e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Zip PF02535.17 OAJ32648.1 - 0.27 10.1 3.5 0.35 9.8 2.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 OAJ32648.1 - 0.36 9.0 3.8 0.53 8.5 2.6 1.3 1 0 0 1 1 1 0 Transmembrane protein SMC_N PF02463.14 OAJ32649.1 - 6.6e-61 205.3 0.0 2.7e-60 203.3 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 OAJ32649.1 - 4.5e-28 97.6 1.4 2.3e-27 95.3 0.1 2.9 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 OAJ32649.1 - 7.2e-17 62.2 0.7 1.1e-07 32.0 0.0 3.8 4 0 0 4 4 4 3 AAA domain AAA_23 PF13476.1 OAJ32649.1 - 3.5e-15 56.8 0.2 3.5e-15 56.8 0.2 6.4 2 2 2 5 5 5 1 AAA domain AAA_29 PF13555.1 OAJ32649.1 - 3.2e-08 32.9 0.3 1.2e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.1 OAJ32649.1 - 0.00023 20.3 0.0 0.00073 18.7 0.0 4.7 5 0 0 5 5 5 2 AAA ATPase domain SbcCD_C PF13558.1 OAJ32649.1 - 0.00047 20.0 0.0 0.0021 17.9 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Reo_sigmaC PF04582.7 OAJ32649.1 - 0.0057 15.8 27.2 0.11 11.6 0.7 4.4 2 2 2 4 4 4 3 Reovirus sigma C capsid protein ABC_tran PF00005.22 OAJ32649.1 - 0.061 13.6 0.0 0.061 13.6 0.0 6.0 4 3 0 4 4 4 0 ABC transporter AAA_17 PF13207.1 OAJ32649.1 - 0.71 10.7 0.0 0.71 10.7 0.0 3.7 3 2 1 4 4 4 0 AAA domain Ribosomal_L18e PF00828.14 OAJ32650.1 - 2.2e-34 118.6 0.6 2.8e-34 118.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 COG2 PF06148.6 OAJ32651.1 - 1.9e-12 47.2 0.8 5.6e-12 45.6 0.6 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 OAJ32651.1 - 0.0022 18.0 0.0 0.035 14.2 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3510) BAR PF03114.13 OAJ32651.1 - 0.0092 15.5 0.4 3.1 7.2 0.1 2.6 2 0 0 2 2 2 2 BAR domain JAB PF01398.16 OAJ32652.1 - 2.2e-07 30.5 0.0 1.7e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease F-box-like PF12937.2 OAJ32653.1 - 0.052 13.2 0.0 0.46 10.2 0.0 2.6 2 0 0 2 2 2 0 F-box-like DNA_pol_B PF00136.16 OAJ32654.1 - 1.4e-114 383.4 0.0 1.8e-114 383.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 OAJ32654.1 - 1.8e-48 164.3 0.0 3.4e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 OAJ32654.1 - 1e-28 100.1 0.0 1.7e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 OAJ32654.1 - 7e-23 80.2 3.9 2.1e-22 78.7 2.7 1.9 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal SH3_1 PF00018.23 OAJ32655.1 - 1.3e-17 62.8 0.0 1.7e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ32655.1 - 5.7e-14 51.4 0.1 7.4e-14 51.0 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ32655.1 - 2.6e-12 46.0 0.0 3.2e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain Lamp PF01299.12 OAJ32655.1 - 0.037 13.1 0.1 0.039 13.0 0.1 1.0 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) DUF3104 PF11302.3 OAJ32655.1 - 0.085 12.2 0.1 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Aminotran_3 PF00202.16 OAJ32657.1 - 5.9e-98 327.8 0.1 7.1e-98 327.5 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 OAJ32657.1 - 2.2e-05 23.6 0.0 0.0015 17.5 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class I and II Spc24 PF08286.6 OAJ32658.1 - 5.6e-05 22.8 0.1 0.0046 16.6 0.0 2.3 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Muted PF14942.1 OAJ32658.1 - 0.0011 18.8 3.5 0.0018 18.1 2.4 1.2 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein ABC_membrane_2 PF06472.10 OAJ32658.1 - 0.018 14.1 0.4 0.029 13.4 0.3 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 LpxK PF02606.9 OAJ32658.1 - 0.12 11.2 0.9 0.2 10.5 0.6 1.3 1 1 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase DUF342 PF03961.8 OAJ32658.1 - 0.17 10.2 0.6 0.23 9.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Latarcin PF10279.4 OAJ32658.1 - 1.2 9.3 4.9 1.3 9.2 0.9 2.2 2 0 0 2 2 2 0 Latarcin precursor Med21 PF11221.3 OAJ32658.1 - 1.4 8.8 4.1 40 4.1 1.2 3.1 3 0 0 3 3 3 0 Subunit 21 of Mediator complex Mnd1 PF03962.10 OAJ32658.1 - 2.1 7.9 7.1 57 3.2 0.6 2.0 1 1 1 2 2 2 0 Mnd1 family zf-CCCH PF00642.19 OAJ32659.1 - 7e-13 47.9 14.6 8.4e-07 28.5 1.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 OAJ32659.1 - 0.0009 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CART PF06373.6 OAJ32659.1 - 0.26 11.2 2.8 6.1 6.8 0.2 2.5 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) CBFD_NFYB_HMF PF00808.18 OAJ32661.1 - 3.6e-16 58.9 0.1 7.2e-16 58.0 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 OAJ32661.1 - 0.004 16.8 0.0 0.0068 16.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 OAJ32661.1 - 0.074 13.1 0.0 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Proteasome PF00227.21 OAJ32664.1 - 3.2e-58 196.1 0.1 4.9e-58 195.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAJ32664.1 - 2.3e-15 55.5 1.3 6.9e-15 54.0 0.3 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Methyltransf_16 PF10294.4 OAJ32666.1 - 1.2e-15 57.4 0.0 6.4e-15 55.0 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Phage_min_tail PF05939.8 OAJ32666.1 - 0.041 13.8 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Phage minor tail protein DEAD PF00270.24 OAJ32667.1 - 1.5e-24 86.3 0.0 2.9e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 OAJ32667.1 - 7.2e-13 48.9 1.0 4.3e-12 46.4 0.7 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 OAJ32667.1 - 5e-11 42.2 0.0 1.7e-10 40.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mito_carr PF00153.22 OAJ32667.1 - 2.1e-10 40.1 0.1 1.6e-06 27.7 0.0 2.7 2 0 0 2 2 2 2 Mitochondrial carrier protein CDT1 PF08839.6 OAJ32667.1 - 9.9e-06 25.5 0.0 2.3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.10 OAJ32667.1 - 0.0023 17.7 0.2 0.017 14.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ox_reductase_C PF08635.5 OAJ32668.1 - 2e-77 257.4 0.1 3.1e-77 256.8 0.1 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 OAJ32668.1 - 3.9e-23 82.2 0.0 1.1e-22 80.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold RNA_pol_L_2 PF13656.1 OAJ32669.1 - 3.6e-28 96.8 0.0 4.8e-28 96.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 OAJ32669.1 - 4.1e-09 35.4 0.0 5.8e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain zf-C2H2 PF00096.21 OAJ32669.1 - 0.065 13.5 0.5 0.12 12.7 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Kinesin-related PF06548.6 OAJ32669.1 - 0.095 11.2 2.8 0.12 10.8 1.9 1.1 1 0 0 1 1 1 0 Kinesin-related RRM_1 PF00076.17 OAJ32670.1 - 1.1e-15 57.0 0.1 1.8e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ32670.1 - 1e-12 47.8 0.0 2e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ32670.1 - 4.9e-08 32.7 0.0 7.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ32670.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif MR_MLE PF01188.16 OAJ32670.1 - 0.097 13.2 0.1 0.19 12.2 0.0 1.5 1 1 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain efThoc1 PF11957.3 OAJ32671.1 - 1.4e-51 175.4 22.4 4.9e-46 157.2 12.5 5.5 2 1 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Cornifin PF02389.10 OAJ32672.1 - 0.0033 17.2 12.0 0.0033 17.2 8.3 2.3 1 1 0 2 2 2 1 Cornifin (SPRR) family Macoilin PF09726.4 OAJ32672.1 - 0.46 8.7 3.9 0.73 8.0 2.7 1.2 1 0 0 1 1 1 0 Transmembrane protein Sporozoite_P67 PF05642.6 OAJ32672.1 - 6.6 4.4 17.0 8.8 4.0 10.6 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen SSP160 PF06933.6 OAJ32672.1 - 8.9 4.1 22.3 14 3.4 15.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ubiquitin PF00240.18 OAJ32673.1 - 3e-34 116.2 1.1 3e-34 116.2 0.7 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.14 OAJ32673.1 - 3.4e-26 90.7 0.7 7e-26 89.7 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 OAJ32673.1 - 8.7e-20 70.1 0.8 1.5e-19 69.4 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAJ32673.1 - 2.4e-06 27.7 0.5 4.6e-05 23.5 0.1 2.6 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAJ32673.1 - 0.0002 21.0 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 OAJ32673.1 - 0.00057 19.7 0.7 0.0012 18.7 0.5 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 OAJ32673.1 - 0.004 17.3 0.6 0.0054 16.8 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2207 PF09972.4 OAJ32673.1 - 0.0062 15.1 0.3 0.0072 14.9 0.2 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) IBR PF01485.16 OAJ32673.1 - 0.016 15.0 0.8 0.027 14.3 0.6 1.4 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 OAJ32673.1 - 0.041 13.9 0.8 0.096 12.7 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 OAJ32673.1 - 0.077 11.3 3.3 0.66 8.2 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain TPR_11 PF13414.1 OAJ32675.1 - 5.4e-10 38.7 23.3 6.5e-05 22.5 0.0 9.3 8 2 1 10 10 10 4 TPR repeat TPR_1 PF00515.23 OAJ32675.1 - 6.2e-10 38.2 17.4 0.24 11.0 0.0 8.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ32675.1 - 7.3e-08 31.7 25.4 0.16 11.9 0.1 10.1 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ32675.1 - 2.3e-07 31.0 29.7 0.36 11.2 0.0 8.9 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ32675.1 - 2.4e-07 30.4 2.6 6.6 7.2 0.2 8.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ32675.1 - 4.1e-07 29.8 19.0 0.00012 21.9 0.0 8.5 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ32675.1 - 5.8e-06 25.7 5.1 2.9 7.8 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ32675.1 - 0.0013 18.8 2.2 0.15 12.2 0.0 4.7 5 1 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 OAJ32675.1 - 0.0024 18.3 0.7 0.0024 18.3 0.5 12.1 13 1 0 13 13 13 3 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ32675.1 - 0.0098 16.2 0.3 0.0098 16.2 0.2 10.3 12 0 0 12 12 12 1 Tetratricopeptide repeat NADH-u_ox-rdase PF10785.4 OAJ32676.1 - 9.9e-31 105.8 0.1 1.5e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 OAJ32676.1 - 3.4e-11 42.6 0.0 5.4e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Acyl_transf_3 PF01757.17 OAJ32676.1 - 0.0057 15.5 0.8 0.0076 15.1 0.5 1.1 1 0 0 1 1 1 1 Acyltransferase family POP1 PF06978.6 OAJ32677.1 - 4e-31 108.1 13.6 4e-31 108.1 9.4 4.0 4 0 0 4 4 4 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 OAJ32677.1 - 6.7e-10 38.6 6.1 2.1e-06 27.5 0.0 3.7 3 0 0 3 3 3 2 POPLD (NUC188) domain Peptidase_M28 PF04389.12 OAJ32678.1 - 1.3e-12 47.8 0.0 2.7e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 OAJ32678.1 - 1.4e-07 31.1 0.0 3.5e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 PA domain TFR_dimer PF04253.10 OAJ32678.1 - 1.6e-07 30.9 0.0 5.9e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 Transferrin receptor-like dimerisation domain Actin PF00022.14 OAJ32679.1 - 1.2e-49 168.7 0.0 5.4e-49 166.6 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 OAJ32679.1 - 0.0066 15.0 0.0 0.016 13.7 0.0 1.6 1 0 0 1 1 1 1 MreB/Mbl protein SDA1 PF05285.7 OAJ32679.1 - 0.63 9.2 15.4 2.1 7.5 9.9 2.0 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.5 OAJ32679.1 - 9.1 5.2 17.6 23 3.8 12.2 1.6 1 0 0 1 1 1 0 BUD22 tRNA-synt_2 PF00152.15 OAJ32681.1 - 1.5e-84 283.6 0.0 1.8e-84 283.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAJ32681.1 - 8.9e-11 41.4 0.0 3.4e-10 39.6 0.0 2.1 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 OAJ32681.1 - 4.1e-08 32.7 0.1 8e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 OAJ32681.1 - 0.0062 16.1 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti-like PF12869.2 OAJ32681.1 - 0.08 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 tRNA_anti-like UDPGP PF01704.13 OAJ32682.1 - 9.1e-25 87.0 0.0 3.9e-16 58.5 0.0 2.7 2 1 1 3 3 3 2 UTP--glucose-1-phosphate uridylyltransferase Lipase_3 PF01764.20 OAJ32683.1 - 2e-12 46.9 0.0 4.7e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Phyto_Pns9_10 PF05878.6 OAJ32683.1 - 4.2 6.2 2.0 8.1 5.3 1.4 1.4 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Fungal_trans PF04082.13 OAJ32684.1 - 1.4e-11 43.7 0.6 0.0001 21.2 0.0 2.8 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ32684.1 - 2.2e-05 24.2 8.8 4.1e-05 23.3 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.4 OAJ32684.1 - 0.065 13.0 0.8 0.14 11.8 0.5 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Tom22 PF04281.8 OAJ32684.1 - 0.49 9.9 0.0 0.49 9.9 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 Ribosomal_S6e PF01092.14 OAJ32685.1 - 2.8e-57 191.8 0.2 6.1e-57 190.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e Ribosomal_S13_N PF08069.7 OAJ32686.1 - 6.1e-30 102.8 0.3 1e-29 102.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 OAJ32686.1 - 2.1e-21 75.4 0.2 2.8e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 OAJ32686.1 - 0.098 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain DUF2514 PF10721.4 OAJ32687.1 - 0.019 14.6 1.4 0.022 14.4 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Tyrosinase PF00264.15 OAJ32690.1 - 9.3e-35 120.7 0.1 1.4e-34 120.2 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF21 PF01595.15 OAJ32691.1 - 3.1e-36 124.3 0.9 5.1e-36 123.6 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 OAJ32691.1 - 8.4e-09 35.0 0.1 0.0073 16.0 0.0 2.9 3 0 0 3 3 3 2 CBS domain PIN_4 PF13638.1 OAJ32692.1 - 1.5e-18 67.1 2.1 2.1e-18 66.6 0.1 2.2 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.4 OAJ32692.1 - 3.2e-11 42.9 0.0 6.1e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain eIF3_subunit PF08597.5 OAJ32692.1 - 0.079 12.5 10.6 0.16 11.5 7.3 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DNA_pol_phi PF04931.8 OAJ32692.1 - 0.96 7.1 6.5 1.4 6.5 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF1765 PF08578.5 OAJ32693.1 - 1.4e-28 99.5 1.6 2.1e-28 98.8 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) GATase_5 PF13507.1 OAJ32694.1 - 2.9e-91 304.9 0.0 4.7e-91 304.2 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 OAJ32694.1 - 2.1e-43 147.9 3.0 1.5e-21 77.0 0.0 2.7 2 1 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 OAJ32694.1 - 3.9e-21 75.0 0.0 1.3e-20 73.3 0.0 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain TFR_dimer PF04253.10 OAJ32695.1 - 1.3e-13 50.6 0.0 5e-13 48.7 0.0 1.9 1 1 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 OAJ32695.1 - 1.5e-12 47.5 0.5 3.8e-12 46.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 OAJ32695.1 - 1.5e-05 24.5 0.1 3.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 OAJ32695.1 - 0.0027 17.2 0.0 0.0065 16.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Cep57_CLD PF14073.1 OAJ32695.1 - 0.15 11.8 0.1 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 SOBP PF15279.1 OAJ32696.1 - 3.2 8.0 8.2 6.4 7.0 5.7 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein Pyr_redox_2 PF07992.9 OAJ32698.1 - 3.4e-22 79.3 0.7 1.8e-21 76.9 0.5 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 OAJ32698.1 - 1.9e-14 52.9 0.0 3.8e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 OAJ32698.1 - 6.6e-13 48.8 8.2 3.2e-11 43.4 0.2 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 OAJ32698.1 - 6.8e-07 28.9 0.0 2.3e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox_3 PF13738.1 OAJ32698.1 - 3e-05 24.1 0.7 0.001 19.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 OAJ32698.1 - 0.0049 17.1 0.0 0.015 15.5 0.0 1.9 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.1 OAJ32698.1 - 0.009 14.9 0.2 9.8 4.9 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAJ32698.1 - 0.085 12.6 0.5 1.8 8.3 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding FBPase PF00316.15 OAJ32700.1 - 5.9e-129 429.5 0.0 6.4e-129 429.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 OAJ32700.1 - 0.00082 18.7 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Inositol monophosphatase family AAA PF00004.24 OAJ32701.1 - 5.4e-32 110.7 0.0 1.2e-31 109.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ32701.1 - 3.3e-08 33.7 0.0 1.2e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ32701.1 - 8e-08 32.4 0.1 4.2e-07 30.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 OAJ32701.1 - 1.4e-06 27.8 0.2 0.038 13.4 0.0 2.7 2 1 1 3 3 2 2 AAA domain AAA_17 PF13207.1 OAJ32701.1 - 2e-06 28.6 0.0 4.6e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 OAJ32701.1 - 4.7e-06 26.6 0.0 1.3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 OAJ32701.1 - 4.7e-06 26.5 0.0 2e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 OAJ32701.1 - 1e-05 25.3 0.3 0.00076 19.2 0.2 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 OAJ32701.1 - 2.4e-05 24.6 0.0 4.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ32701.1 - 7.6e-05 22.3 0.0 0.00028 20.5 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_24 PF13479.1 OAJ32701.1 - 0.0001 21.9 0.0 0.00028 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 OAJ32701.1 - 0.00032 20.6 0.0 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 OAJ32701.1 - 0.00035 20.2 0.2 0.0027 17.3 0.1 2.2 1 1 0 1 1 1 1 NACHT domain PhoH PF02562.11 OAJ32701.1 - 0.00064 19.0 0.0 0.21 10.8 0.0 3.2 3 0 0 3 3 3 1 PhoH-like protein UPF0079 PF02367.12 OAJ32701.1 - 0.00091 18.8 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 OAJ32701.1 - 0.0016 18.1 0.3 0.0078 15.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 OAJ32701.1 - 0.0026 17.5 0.1 0.0063 16.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 OAJ32701.1 - 0.003 17.7 0.0 0.0069 16.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 OAJ32701.1 - 0.0032 16.9 0.0 0.0079 15.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 OAJ32701.1 - 0.0039 17.1 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAJ32701.1 - 0.0042 16.1 0.0 0.0079 15.2 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 OAJ32701.1 - 0.0044 16.5 0.0 0.0087 15.6 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 OAJ32701.1 - 0.0051 15.9 0.0 0.01 14.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin KAP_NTPase PF07693.9 OAJ32701.1 - 0.0051 15.8 0.0 0.87 8.5 0.0 2.3 1 1 1 2 2 2 1 KAP family P-loop domain DUF815 PF05673.8 OAJ32701.1 - 0.0058 15.5 0.0 0.041 12.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF2075 PF09848.4 OAJ32701.1 - 0.0063 15.5 0.0 0.0095 14.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 OAJ32701.1 - 0.0069 15.9 0.1 0.045 13.3 0.0 2.3 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.8 OAJ32701.1 - 0.017 13.8 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_3 PF07726.6 OAJ32701.1 - 0.025 14.1 0.1 0.27 10.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 OAJ32701.1 - 0.029 13.5 0.0 0.15 11.1 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 OAJ32701.1 - 0.031 14.5 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 OAJ32701.1 - 0.035 14.4 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 OAJ32701.1 - 0.059 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.1 OAJ32701.1 - 0.069 11.5 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain eRF1_1 PF03463.10 OAJ32702.1 - 2.2e-52 176.1 0.0 3.4e-52 175.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 OAJ32702.1 - 5.6e-23 81.7 0.0 8.6e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 OAJ32702.1 - 3.1e-22 78.9 0.0 5.8e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 DUF2407 PF10302.4 OAJ32703.1 - 1.8e-12 47.2 1.6 4.6e-11 42.7 1.1 2.8 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2407_C PF13373.1 OAJ32703.1 - 1.4e-10 41.2 5.1 3.2e-09 36.8 1.6 3.1 2 1 0 2 2 2 1 DUF2407 C-terminal domain ubiquitin PF00240.18 OAJ32703.1 - 0.0049 16.2 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ifi-6-16 PF06140.8 OAJ32704.1 - 8e-05 22.3 10.7 0.00012 21.8 7.4 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF1576 PF07613.6 OAJ32704.1 - 0.051 13.0 7.9 0.069 12.6 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) Sugar_tr PF00083.19 OAJ32705.1 - 1.2e-20 73.5 18.6 2.3e-16 59.4 5.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ32705.1 - 2.9e-11 42.6 34.0 1e-10 40.8 23.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_S10 PF00450.17 OAJ32707.1 - 6.7e-91 305.5 0.0 6.9e-79 265.9 0.0 2.5 2 1 0 2 2 2 2 Serine carboxypeptidase Sin3_corepress PF08295.7 OAJ32707.1 - 0.21 11.3 0.3 1.7 8.4 0.0 2.4 3 0 0 3 3 3 0 Sin3 family co-repressor PQ-loop PF04193.9 OAJ32708.1 - 1.7e-23 81.9 0.5 4.1e-13 48.6 0.0 2.7 3 0 0 3 3 3 2 PQ loop repeat Zn_clus PF00172.13 OAJ32709.1 - 6.6e-05 22.7 11.6 0.00011 21.9 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.9 OAJ32709.1 - 4.7 5.1 6.2 7.3 4.4 2.0 2.2 2 0 0 2 2 2 0 CDC45-like protein FAM176 PF14851.1 OAJ32709.1 - 6.8 6.3 6.3 23 4.6 0.7 2.7 2 0 0 2 2 2 0 FAM176 family F-actin_cap_A PF01267.12 OAJ32710.1 - 2.5e-63 213.6 0.0 4.2e-63 212.9 0.0 1.3 1 1 0 1 1 1 1 F-actin capping protein alpha subunit DUF4644 PF15486.1 OAJ32710.1 - 1.1 9.1 4.4 0.35 10.8 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4644) TPR_2 PF07719.12 OAJ32712.1 - 2.7e-07 29.9 0.7 0.81 9.7 0.1 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ32712.1 - 8.5e-06 25.9 11.2 0.68 10.7 0.0 5.2 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ32712.1 - 9.3e-05 22.9 5.5 0.35 11.6 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ32712.1 - 0.00036 20.1 0.3 15 5.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ32712.1 - 0.00097 18.7 1.0 4.4 7.0 0.2 3.7 3 1 1 4 4 4 3 TPR repeat TPR_19 PF14559.1 OAJ32712.1 - 0.0059 16.9 8.7 15 6.0 0.1 4.9 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ32712.1 - 0.028 14.0 0.7 34 4.2 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ32712.1 - 0.058 13.2 2.1 8.7 6.2 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_C48 PF02902.14 OAJ32713.1 - 6.1e-24 84.8 0.1 2.2e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain GAS2 PF02187.12 OAJ32714.1 - 0.075 12.8 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain FUSC PF04632.7 OAJ32715.1 - 3.6 5.8 5.1 7 4.9 3.5 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family HALZ PF02183.13 OAJ32715.1 - 5.4 6.8 11.0 6.6 6.5 0.0 4.0 2 1 1 3 3 3 0 Homeobox associated leucine zipper RRM_1 PF00076.17 OAJ32716.1 - 6.9e-18 64.0 0.0 1.1e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ32716.1 - 2.5e-15 56.1 0.2 7.2e-15 54.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ32716.1 - 6.4e-08 32.3 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2763 PF10961.3 OAJ32716.1 - 6.5 7.2 13.7 0.74 10.2 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) DUF59 PF01883.14 OAJ32717.1 - 3e-09 36.7 0.0 5.5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 Sporozoite_P67 PF05642.6 OAJ32717.1 - 0.072 10.9 1.6 0.095 10.5 1.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HsbA PF12296.3 OAJ32718.1 - 0.031 14.1 1.1 0.37 10.6 0.3 2.3 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.7 OAJ32718.1 - 0.034 13.9 1.5 0.88 9.3 0.6 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.6 OAJ32718.1 - 0.037 14.0 0.2 0.96 9.4 0.2 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) RNase_P_pop3 PF08228.6 OAJ32718.1 - 0.12 12.1 0.2 0.28 11.0 0.1 1.6 1 1 0 1 1 1 0 RNase P subunit Pop3 YbjQ_1 PF01906.12 OAJ32718.1 - 0.14 12.5 1.0 9 6.7 0.1 2.9 2 1 2 4 4 4 0 Putative heavy-metal-binding IF4E PF01652.13 OAJ32719.1 - 3.1e-47 160.1 0.0 4.4e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Cation_efflux PF01545.16 OAJ32720.1 - 3e-39 134.8 11.8 9.9e-39 133.1 8.2 1.8 1 1 0 1 1 1 1 Cation efflux family LEA_2 PF03168.8 OAJ32721.1 - 0.0083 16.4 0.0 0.025 14.9 0.0 1.9 1 1 1 2 2 2 1 Late embryogenesis abundant protein Cellulase PF00150.13 OAJ32722.1 - 5.1e-09 35.7 0.0 7.3e-08 31.9 0.0 2.4 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Acyltransferase PF01553.16 OAJ32723.1 - 1e-16 60.5 0.1 1.6e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase Tic20 PF09685.5 OAJ32723.1 - 0.13 12.2 2.0 0.31 11.0 1.4 1.6 1 0 0 1 1 1 0 Tic20-like protein Peptidase_M20 PF01546.23 OAJ32724.1 - 1.5e-18 66.9 4.0 6.6e-18 64.8 2.8 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 OAJ32724.1 - 1.3e-15 56.6 16.7 7.3e-07 28.8 0.0 7.9 8 1 1 9 9 9 4 WD domain, G-beta repeat M20_dimer PF07687.9 OAJ32724.1 - 3.9e-09 36.2 0.0 9.3e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain TACI-CRD2 PF09305.5 OAJ32724.1 - 0.055 13.2 0.2 5 7.0 0.0 2.6 2 0 0 2 2 2 0 TACI, cysteine-rich domain VIT1 PF01988.14 OAJ32725.1 - 1.4e-64 217.4 5.9 1.9e-64 217.0 4.1 1.1 1 0 0 1 1 1 1 VIT family Med3 PF11593.3 OAJ32725.1 - 0.88 8.7 3.0 1.2 8.2 2.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Chromate_transp PF02417.10 OAJ32726.1 - 4.9e-53 179.1 32.4 9e-30 103.4 6.7 2.7 3 1 0 3 3 3 2 Chromate transporter Sugar_tr PF00083.19 OAJ32727.1 - 1.4e-28 99.6 22.8 1.8e-19 69.6 5.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ32727.1 - 7.1e-14 51.2 43.5 6.5e-09 34.9 15.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RNase_T PF00929.19 OAJ32728.1 - 2.1e-10 41.1 0.1 2.6e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 Exonuclease PAS_9 PF13426.1 OAJ32728.1 - 0.024 15.0 0.0 0.036 14.4 0.0 1.2 1 0 0 1 1 1 0 PAS domain WD40 PF00400.27 OAJ32729.1 - 4e-43 143.8 14.1 1.3e-08 34.3 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat PFU PF09070.6 OAJ32729.1 - 7.1e-43 145.3 0.1 1.2e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 OAJ32729.1 - 4.5e-36 124.0 0.0 6e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 PUL domain PQQ_3 PF13570.1 OAJ32729.1 - 0.11 12.8 1.8 37 4.7 0.0 4.4 4 0 0 4 4 4 0 PQQ-like domain ThiF PF00899.16 OAJ32730.1 - 1.2e-44 151.4 0.1 1.6e-28 99.2 0.1 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 OAJ32730.1 - 7.4e-42 142.4 0.0 1.6e-41 141.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 OAJ32730.1 - 1.8e-41 139.5 5.7 1.2e-27 95.2 0.2 3.3 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 OAJ32730.1 - 6.2e-25 86.3 2.0 3.7e-21 74.2 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Pyr_redox PF00070.22 OAJ32730.1 - 0.54 10.7 2.1 44 4.5 0.0 3.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RNase_T PF00929.19 OAJ32731.1 - 8.6e-08 32.6 0.0 1e-07 32.4 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF4363 PF14276.1 OAJ32731.1 - 0.024 14.3 0.2 0.037 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4363)