# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF3605 PF12239.3 OAI95151.1 - 4.8e-05 23.2 0.0 5.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) RHH_1 PF01402.16 OAI95152.1 - 7.6e-07 28.7 0.6 7.6e-07 28.7 0.4 2.0 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family TraY PF05509.6 OAI95152.1 - 1.7e-05 24.5 1.0 3.6e-05 23.4 0.7 1.5 1 0 0 1 1 1 1 TraY domain HicB PF05534.7 OAI95152.1 - 0.025 14.1 0.1 0.059 12.9 0.1 1.7 1 0 0 1 1 1 0 HicB family DUF4407 PF14362.1 OAI95154.1 - 0.067 12.1 0.3 0.092 11.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDE_Tnp_4 PF13359.1 OAI95155.1 - 1.8e-27 95.9 0.0 2.2e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAI95155.1 - 0.0025 17.2 0.0 0.009 15.4 0.0 1.9 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 OAI95155.1 - 0.0031 17.0 0.1 0.018 14.5 0.1 2.1 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.1 OAI95155.1 - 0.011 15.8 0.1 0.026 14.7 0.1 1.5 1 0 0 1 1 1 0 Transposase DDE domain BCA_ABC_TP_C PF12399.3 OAI95155.1 - 0.015 14.9 0.3 0.13 12.0 0.0 2.3 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter BLUF PF04940.7 OAI95159.1 - 6.1e-31 105.9 0.0 9.1e-31 105.4 0.0 1.3 1 0 0 1 1 1 1 Sensors of blue-light using FAD PRA-PH PF01503.12 OAI95164.1 - 1.4e-10 41.2 0.3 2.8e-10 40.3 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 OAI95164.1 - 0.00011 22.0 0.1 0.00017 21.4 0.1 1.2 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain TonB_dep_Rec PF00593.19 OAI95165.1 - 8.6e-30 104.5 18.5 1.2e-29 104.0 12.8 1.2 1 0 0 1 1 1 1 TonB dependent receptor DUF4278 PF14105.1 OAI95165.1 - 0.89 9.5 12.1 0.69 9.8 0.7 4.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4278) DsbC PF11412.3 OAI95177.1 - 4.5e-21 74.8 0.0 6e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Disulphide bond corrector protein DsbC DsbD PF02683.10 OAI95177.1 - 6.2e-18 65.1 16.9 7.5e-18 64.8 11.7 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.1 OAI95177.1 - 2.2e-12 47.1 24.9 3.2e-12 46.6 17.3 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region TrbC PF04956.8 OAI95180.1 - 0.086 12.8 0.3 0.086 12.8 0.2 1.0 1 0 0 1 1 1 0 TrbC/VIRB2 family Sigma70_r2 PF04542.9 OAI95188.1 - 9.7e-17 60.3 0.1 1.6e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.7 OAI95188.1 - 3.9e-15 55.0 0.1 1.3e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.11 OAI95188.1 - 6.1e-07 28.6 0.0 1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.6 OAI95188.1 - 7e-05 22.5 0.0 8.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 ECF sigma factor DUF134 PF02001.11 OAI95188.1 - 0.0018 18.1 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF134 GerE PF00196.14 OAI95188.1 - 0.0096 15.2 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Hexokinase_2 PF03727.11 OAI95188.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.4 1 1 0 1 1 1 0 Hexokinase ADSL_C PF10397.4 OAI95188.1 - 0.12 12.3 0.1 1.7 8.7 0.0 2.3 1 1 0 1 1 1 0 Adenylosuccinate lyase C-terminus DUF4347 PF14252.1 OAI95195.1 - 3e-54 182.9 1.8 4e-54 182.5 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4347) DNA_pol_viral_N PF00242.12 OAI95200.1 - 0.085 11.8 7.0 0.1 11.6 4.9 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 OAI95200.1 - 0.22 9.7 7.8 0.23 9.7 5.4 1.2 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 OAI95200.1 - 0.85 9.0 30.8 1.9 7.9 21.3 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF572 PF04502.8 OAI95200.1 - 3.2 6.8 13.1 4.7 6.3 9.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) RAP1 PF07218.6 OAI95200.1 - 5.3 5.0 9.0 6.6 4.6 6.2 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SnoaL_2 PF12680.2 OAI95208.1 - 7.8e-05 23.0 0.0 0.00013 22.3 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.11 OAI95209.1 - 1.6e-13 50.1 20.7 1.8e-13 49.9 14.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 OAI95209.1 - 0.07 11.5 14.7 0.8 8.0 2.0 2.0 1 1 1 2 2 2 0 MFS/sugar transport protein UPF0060 PF02694.10 OAI95209.1 - 0.59 10.1 9.0 4.7 7.2 0.2 2.5 1 1 1 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Coa1 PF08695.5 OAI95212.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 MSP1_C PF07462.6 OAI95212.1 - 0.49 8.7 3.4 0.65 8.3 2.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3464 PF11947.3 OAI95215.1 - 0.0084 15.5 2.3 0.0084 15.5 1.6 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3464) FAM60A PF15396.1 OAI95215.1 - 3.3 7.3 21.2 0.15 11.7 6.0 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Cyt-b5 PF00173.23 OAI95218.1 - 1.6e-21 75.8 0.0 2e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GlcNAc_2-epim PF07221.6 OAI95221.1 - 1.4e-47 162.3 0.1 1.7e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) S-methyl_trans PF02574.11 OAI95222.1 - 7e-18 64.9 0.0 8.5e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Trns_repr_metal PF02583.12 OAI95224.1 - 4.3e-22 78.0 0.3 4.7e-22 77.9 0.2 1.1 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor Pkinase PF00069.20 OAI95228.1 - 9.9e-30 103.5 0.0 1.2e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI95228.1 - 2.4e-17 62.8 0.0 3e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI95228.1 - 3.7e-07 29.3 0.0 4.8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like HATPase_c PF02518.21 OAI95233.1 - 3.5e-19 68.5 0.0 8.8e-19 67.2 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 OAI95233.1 - 6e-07 29.3 0.5 1.6e-06 27.9 0.4 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 OAI95233.1 - 0.049 13.3 0.0 0.19 11.4 0.0 1.9 1 1 0 1 1 1 0 GHKL domain B12-binding PF02310.14 OAI95233.1 - 0.061 13.1 0.3 0.56 10.0 0.2 2.3 1 1 0 1 1 1 0 B12 binding domain Nuc_deoxyrib_tr PF05014.10 OAI95233.1 - 0.097 12.5 0.1 0.41 10.5 0.0 2.0 3 0 0 3 3 3 0 Nucleoside 2-deoxyribosyltransferase RVT_1 PF00078.22 OAI95239.1 - 8e-12 44.9 0.0 1.8e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Afi1 PF07792.7 OAI95243.1 - 3.1e-44 150.4 0.0 4.3e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.4 OAI95243.1 - 2.1e-06 26.4 0.0 8e-06 24.5 0.0 1.8 1 1 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 OAI95243.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) DUF461 PF04314.8 OAI95250.1 - 0.0027 17.3 0.0 0.0036 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF461) Glyco_hydro_9 PF00759.14 OAI95259.1 - 2.5e-18 66.2 0.1 3.2e-09 36.2 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 9 PP2C PF00481.16 OAI95259.1 - 5.2e-08 32.6 0.0 7.5e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Peripla_BP_6 PF13458.1 OAI95267.1 - 1.8e-29 103.1 2.4 2e-29 103.0 1.7 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.1 OAI95267.1 - 5.5e-05 22.0 0.0 7e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain DUF3435 PF11917.3 OAI95268.1 - 3.7e-12 45.6 0.0 4.7e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) HHH_5 PF14520.1 OAI95268.1 - 0.011 15.8 0.0 0.13 12.4 0.0 2.5 2 1 0 2 2 2 0 Helix-hairpin-helix domain DUF2483 PF10656.4 OAI95268.1 - 0.022 14.8 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2483) Myc_N PF01056.13 OAI95271.1 - 0.00048 19.3 0.4 0.00052 19.2 0.2 1.1 1 0 0 1 1 1 1 Myc amino-terminal region PBP1_TM PF14812.1 OAI95271.1 - 0.0021 18.3 0.2 0.0031 17.8 0.2 1.3 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal TIMELESS_C PF05029.8 OAI95271.1 - 0.0082 15.1 0.5 0.0087 15.0 0.4 1.0 1 0 0 1 1 1 1 Timeless protein C terminal region Ribosomal_60s PF00428.14 OAI95271.1 - 0.02 15.3 1.8 0.028 14.8 1.3 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein SLAIN PF15301.1 OAI95271.1 - 0.021 13.9 1.5 0.024 13.8 1.0 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family Prok-TraM PF09228.5 OAI95271.1 - 0.029 14.5 0.1 0.035 14.2 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM CENP-B_dimeris PF09026.5 OAI95271.1 - 0.032 14.4 0.3 0.038 14.2 0.2 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BSP_II PF05432.6 OAI95271.1 - 0.035 13.3 3.7 0.041 13.1 2.5 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 OAI95271.1 - 0.037 13.5 2.1 0.047 13.2 1.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin RNA_polI_A34 PF08208.6 OAI95271.1 - 0.16 11.6 1.5 0.19 11.3 1.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Asp_protease_2 PF13650.1 OAI95276.1 - 0.00015 22.1 0.0 0.00047 20.5 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI95276.1 - 0.0027 17.4 0.0 0.03 14.1 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAI95276.1 - 0.0052 16.6 0.0 0.02 14.8 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease DUF1302 PF06980.6 OAI95278.1 - 1e-58 199.3 0.6 1.8e-58 198.4 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1302) E1_dh PF00676.15 OAI95281.1 - 2e-38 131.8 0.0 2.3e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component ACR_tran PF00873.14 OAI95282.1 - 4.2e-84 282.7 0.5 4.7e-84 282.5 0.4 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family PADR1 PF08063.7 OAI95290.1 - 0.078 12.3 0.2 0.2 11.0 0.1 1.6 1 0 0 1 1 1 0 PADR1 (NUC008) domain P-II PF00543.17 OAI95292.1 - 0.022 15.2 0.0 0.024 15.1 0.0 1.1 1 0 0 1 1 1 0 Nitrogen regulatory protein P-II DUF1538 PF07556.6 OAI95293.1 - 1e-49 168.5 12.9 1.2e-49 168.3 9.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1538) Histone PF00125.19 OAI95297.1 - 2.6e-21 75.5 0.2 3.2e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAI95297.1 - 1.7e-07 31.1 0.1 2.5e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 OAI95297.1 - 0.00011 22.3 0.0 0.00016 21.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Bt_P21 PF05560.6 OAI95297.1 - 0.085 12.2 0.0 0.092 12.1 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Glyco_hydro_18 PF00704.23 OAI95299.1 - 1.2e-11 44.7 0.0 1.3e-11 44.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 IF-2 PF11987.3 OAI95300.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Translation-initiation factor 2 DNA_pol_viral_C PF00336.13 OAI95303.1 - 0.005 16.1 0.1 0.0097 15.1 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain NOPS PF08075.6 OAI95306.1 - 0.03 14.7 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 NOPS (NUC059) domain Phage_portal_2 PF05136.8 OAI95306.1 - 0.1 11.0 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Phage portal protein, lambda family MMPL PF03176.10 OAI95307.1 - 0.0021 16.8 6.1 0.0024 16.6 4.3 1.2 1 0 0 1 1 1 1 MMPL family ACR_tran PF00873.14 OAI95307.1 - 0.056 10.8 5.5 0.072 10.4 3.8 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Adaptin_binding PF10199.4 OAI95312.1 - 0.12 12.6 3.1 0.19 12.0 2.1 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF506 PF04720.7 OAI95312.1 - 0.56 9.8 4.2 0.86 9.1 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Orthopox_A36R PF05950.6 OAI95312.1 - 2.6 7.9 11.2 2.8 7.8 6.9 1.7 2 0 0 2 2 2 0 Orthopoxvirus A36R protein SURF2 PF05477.6 OAI95312.1 - 3.2 6.8 7.6 4.5 6.3 5.3 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SSP160 PF06933.6 OAI95312.1 - 4.6 5.1 15.3 5.9 4.7 10.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-CCHC PF00098.18 OAI95318.1 - 0.015 15.1 6.3 0.063 13.2 0.3 2.6 2 0 0 2 2 2 0 Zinc knuckle DUF2996 PF11210.3 OAI95318.1 - 0.11 12.8 0.0 2.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2996) Macoilin PF09726.4 OAI95318.1 - 0.23 9.7 5.1 0.25 9.5 3.5 1.1 1 0 0 1 1 1 0 Transmembrane protein IBR PF01485.16 OAI95318.1 - 0.89 9.4 4.3 6.4 6.7 0.2 2.4 2 0 0 2 2 2 0 IBR domain RAP1 PF07218.6 OAI95318.1 - 7.2 4.5 9.8 11 3.9 6.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) GFO_IDH_MocA PF01408.17 OAI95326.1 - 3.6e-14 53.3 0.0 5.9e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 OAI95326.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Hydrolase PF00702.21 OAI95327.1 - 4.2e-30 105.7 2.8 5.5e-30 105.3 1.9 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAI95327.1 - 4.3e-13 49.8 0.1 6e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAI95327.1 - 6e-08 32.5 0.6 4.7e-05 23.0 0.1 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF4342 PF14242.1 OAI95327.1 - 3.5 7.4 5.7 2 8.2 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) MFS_3 PF05977.8 OAI95331.1 - 4.9e-43 147.0 0.1 5.8e-43 146.8 0.1 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector HTH_IclR PF09339.5 OAI95332.1 - 6.1e-08 32.1 0.0 1.4e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR PF01047.17 OAI95332.1 - 1.8e-05 24.3 0.0 4.7e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.2 OAI95332.1 - 0.00051 19.6 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.1 OAI95332.1 - 0.0088 15.4 0.0 0.021 14.1 0.0 1.7 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.15 OAI95332.1 - 0.02 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator HTH_27 PF13463.1 OAI95332.1 - 0.049 13.9 0.0 0.092 13.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_23 PF13384.1 OAI95332.1 - 0.081 12.5 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_20 PF12840.2 OAI95332.1 - 0.1 12.3 0.1 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain zf-CCHC PF00098.18 OAI95340.1 - 0.088 12.7 4.1 0.13 12.2 2.8 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAI95340.1 - 0.42 10.3 2.0 0.77 9.4 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle PAS_3 PF08447.6 OAI95341.1 - 6.9e-10 38.8 0.0 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 OAI95341.1 - 1.1e-08 34.8 0.0 2.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 OAI95341.1 - 4.3e-07 29.9 0.2 5.2e-06 26.4 0.0 2.5 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.1 OAI95341.1 - 6e-07 29.7 0.0 1.5e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.1 OAI95341.1 - 0.026 14.4 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 PAS domain DUF2865 PF11064.3 OAI95348.1 - 0.098 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2865) GFO_IDH_MocA PF01408.17 OAI95351.1 - 1.4e-24 86.9 0.0 1.7e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 OAI95351.1 - 0.00021 21.6 0.2 0.00026 21.3 0.1 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 OAI95351.1 - 0.005 16.0 0.0 0.0068 15.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 OAI95351.1 - 0.056 12.8 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 OAI95351.1 - 0.076 12.8 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 OAI95351.1 - 0.093 13.1 0.1 0.22 11.9 0.0 1.6 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Nop14 PF04147.7 OAI95353.1 - 0.77 7.6 9.4 0.85 7.4 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family FAD_binding_2 PF00890.19 OAI95357.1 - 2.6e-14 52.9 0.0 2.7e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain TraC_F_IV PF11130.3 OAI95362.1 - 5.7e-15 55.3 0.0 9.2e-12 44.8 0.0 2.5 1 1 1 2 2 2 2 F pilus assembly Type-IV secretion system for plasmid transfer adh_short PF00106.20 OAI95365.1 - 1.5e-23 83.5 4.9 1.7e-23 83.3 3.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAI95365.1 - 2.1e-07 30.7 2.1 2.9e-07 30.3 1.5 1.1 1 0 0 1 1 1 1 KR domain TPR_4 PF07721.9 OAI95365.1 - 0.046 14.1 1.3 0.046 14.1 0.9 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAI95365.1 - 0.093 13.4 0.5 0.24 12.1 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat MR_MLE_C PF13378.1 OAI95365.1 - 0.16 11.9 0.2 0.16 11.9 0.1 2.2 2 1 1 3 3 3 0 Enolase C-terminal domain-like UQ_con PF00179.21 OAI95378.1 - 4.7e-37 126.5 0.0 5.8e-37 126.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Toprim_4 PF13662.1 OAI95380.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.7 2 1 0 2 2 2 0 Toprim domain Phage_integrase PF00589.17 OAI95384.1 - 0.00031 20.4 0.0 0.00049 19.8 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF4431 PF14485.1 OAI95384.1 - 0.063 12.8 0.5 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) rve PF00665.21 OAI95385.1 - 5e-19 68.5 0.0 1e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAI95385.1 - 0.0029 17.1 0.0 0.012 15.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain AXE1 PF05448.7 OAI95387.1 - 0.077 11.4 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) UBN2_2 PF14227.1 OAI95391.1 - 1.3e-13 50.5 0.0 2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAI95391.1 - 5.2e-09 35.9 0.0 1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 OAI95391.1 - 0.06 12.8 0.0 0.15 11.6 0.0 1.5 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Ets PF00178.17 OAI95396.1 - 0.085 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Ets-domain CtnDOT_TraJ PF07863.6 OAI95402.1 - 0.75 10.2 2.7 8.3 6.9 1.9 2.1 1 1 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon UPF0183 PF03676.9 OAI95403.1 - 5.5e-12 44.9 0.0 0.0017 17.0 0.0 3.0 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0183) PALP PF00291.20 OAI95405.1 - 1.1e-19 70.8 0.0 1.2e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAD_binding_8 PF13450.1 OAI95405.1 - 0.043 13.8 0.0 0.51 10.3 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Peptidase_S41 PF03572.13 OAI95405.1 - 0.046 13.1 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S41 DUF1720 PF08226.6 OAI95409.1 - 0.29 11.2 13.8 0.69 10.0 9.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) HAMP PF00672.20 OAI95410.1 - 3.2e-07 30.4 6.0 3.2e-07 30.4 4.2 2.2 2 0 0 2 2 2 1 HAMP domain 4HB_MCP_1 PF12729.2 OAI95410.1 - 1.2e-05 24.7 0.0 1.2e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Four helix bundle sensory module for signal transduction TarH PF02203.10 OAI95410.1 - 0.0072 16.1 0.3 0.0072 16.1 0.2 2.1 2 0 0 2 2 2 1 Tar ligand binding domain homologue Dynactin PF12455.3 OAI95410.1 - 0.032 13.1 0.1 0.035 13.0 0.1 1.1 1 0 0 1 1 1 0 Dynein associated protein HlyD_2 PF12700.2 OAI95412.1 - 9.3e-23 80.8 0.0 1.5e-22 80.1 0.0 1.3 1 1 0 1 1 1 1 HlyD family secretion protein HlyD PF00529.15 OAI95412.1 - 4.5e-19 68.8 24.4 6.3e-19 68.3 16.9 1.2 1 0 0 1 1 1 1 HlyD family secretion protein HlyD_3 PF13437.1 OAI95412.1 - 6.2e-14 52.2 1.0 5.4e-09 36.3 0.0 2.6 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 OAI95412.1 - 5.3e-11 42.0 7.6 4.8e-10 38.9 1.3 3.1 2 1 0 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.17 OAI95412.1 - 7e-05 22.3 0.1 0.025 14.2 0.0 2.8 2 0 0 2 2 2 1 Biotin-requiring enzyme V-SNARE_C PF12352.3 OAI95412.1 - 0.0031 17.5 1.6 0.016 15.2 0.3 2.7 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus OEP PF02321.13 OAI95412.1 - 0.0039 16.8 16.7 0.006 16.2 11.6 1.3 1 0 0 1 1 1 1 Outer membrane efflux protein TPR_19 PF14559.1 OAI95412.1 - 0.018 15.3 2.7 0.018 15.3 1.9 2.7 3 1 0 3 3 3 0 Tetratricopeptide repeat PYNP_C PF07831.8 OAI95412.1 - 0.082 12.3 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain DUF4407 PF14362.1 OAI95412.1 - 0.62 8.9 11.6 2 7.2 7.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SDA1 PF05285.7 OAI95414.1 - 0.55 9.4 7.2 0.75 9.0 5.0 1.2 1 0 0 1 1 1 0 SDA1 Phage_integrase PF00589.17 OAI95416.1 - 0.0003 20.5 0.0 0.00047 19.8 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family ThiF PF00899.16 OAI95424.1 - 3.2e-10 39.9 0.0 4.2e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 OAI95424.1 - 0.042 13.9 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Multi_ubiq PF14452.1 OAI95425.1 - 3.4e-11 42.9 0.0 4.1e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Multiubiquitin DUF1840 PF08895.6 OAI95430.1 - 0.0015 18.5 0.1 0.0052 16.7 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF1840) AMP-binding_C PF13193.1 OAI95431.1 - 1.5e-17 64.3 0.0 1.8e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Oxysterol_BP PF01237.13 OAI95433.1 - 2.5e-52 177.5 0.0 3e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DUF2956 PF11169.3 OAI95433.1 - 0.043 13.7 0.2 0.067 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Serglycin PF04360.7 OAI95436.1 - 0.0023 17.6 1.7 0.0071 16.0 1.2 1.9 1 0 0 1 1 1 1 Serglycin CENP-B_dimeris PF09026.5 OAI95437.1 - 0.011 15.9 1.9 0.011 15.9 1.3 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain rve PF00665.21 OAI95439.1 - 0.021 14.9 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain Cellulase PF00150.13 OAI95441.1 - 5.5e-09 35.6 0.0 8e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CR6_interact PF10147.4 OAI95443.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 HAD PF12710.2 OAI95447.1 - 0.068 13.3 0.0 0.068 13.3 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Nop14 PF04147.7 OAI95450.1 - 2.5 5.9 5.0 3.2 5.5 3.4 1.1 1 0 0 1 1 1 0 Nop14-like family RNase_T PF00929.19 OAI95456.1 - 0.0067 16.7 0.0 0.031 14.5 0.0 1.9 1 1 0 1 1 1 1 Exonuclease ResIII PF04851.10 OAI95458.1 - 7.3e-19 68.3 0.0 3.1e-18 66.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAI95458.1 - 2.1e-10 40.3 0.0 6.6e-10 38.7 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 OAI95458.1 - 2.5e-05 23.2 0.0 9.9e-05 21.2 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 OAI95458.1 - 0.035 14.2 0.1 0.18 11.9 0.0 2.1 1 1 1 2 2 2 0 AAA domain CheR PF01739.13 OAI95461.1 - 7.9e-59 198.2 0.0 1.1e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.10 OAI95461.1 - 5.7e-14 51.2 1.5 1e-13 50.4 1.0 1.5 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Response_reg PF00072.19 OAI95461.1 - 3.2e-08 33.5 0.0 6.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Methyltransf_12 PF08242.7 OAI95461.1 - 8.5e-05 22.9 0.0 0.00046 20.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAI95461.1 - 0.0054 17.0 0.0 0.015 15.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAI95461.1 - 0.0056 17.2 0.0 0.017 15.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAI95461.1 - 0.006 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Dicer_dimer PF03368.9 OAI95463.1 - 5.7e-21 74.0 0.1 1.1e-20 73.2 0.1 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain dsrm PF00035.20 OAI95463.1 - 0.00018 21.9 0.0 0.00045 20.7 0.0 1.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif MRF_C2 PF13888.1 OAI95463.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 UBN2_2 PF14227.1 OAI95467.1 - 5.1e-10 38.9 0.1 7.7e-10 38.3 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAI95467.1 - 5.6e-05 22.9 0.1 8e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAI95467.1 - 0.00014 21.6 17.4 0.00014 21.5 2.0 3.4 3 1 0 3 3 3 2 Zinc knuckle zf-CCHC_3 PF13917.1 OAI95467.1 - 0.023 14.4 1.3 0.059 13.1 0.9 1.7 1 0 0 1 1 1 0 Zinc knuckle Cytochrome_C554 PF13435.1 OAI95467.1 - 0.032 14.2 4.7 0.054 13.5 3.3 1.4 1 0 0 1 1 1 0 Cytochrome c554 and c-prime RVP PF00077.15 OAI95467.1 - 0.065 13.1 0.0 2.1 8.2 0.0 2.4 2 1 0 2 2 2 0 Retroviral aspartyl protease VP4_haemagglut PF00426.13 OAI95467.1 - 0.13 10.2 0.0 0.14 10.0 0.0 1.1 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) zf-CCHC_2 PF13696.1 OAI95467.1 - 0.23 11.0 8.9 0.56 9.7 1.3 2.4 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAI95467.1 - 3.9 7.2 7.9 2.8 7.6 0.9 2.5 2 0 0 2 2 2 0 Zinc knuckle Actin PF00022.14 OAI95469.1 - 1.2e-55 188.5 0.0 1.5e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 Actin DUF2114 PF09887.4 OAI95469.1 - 0.038 12.3 0.0 0.045 12.0 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Antimicrobial_6 PF08036.6 OAI95476.1 - 0.046 13.4 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 Diapausin family of antimicrobial peptide PS_pyruv_trans PF04230.8 OAI95477.1 - 5.7e-06 26.2 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase HAD_2 PF13419.1 OAI95477.1 - 0.00071 19.8 0.9 0.1 12.8 0.5 2.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAI95477.1 - 0.17 12.2 0.0 2.2 8.6 0.0 2.3 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Epimerase PF01370.16 OAI95481.1 - 3.1e-54 183.9 0.0 3.6e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 OAI95481.1 - 5.3e-14 51.7 0.0 6.1e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 OAI95481.1 - 4.7e-13 48.4 0.0 6e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 OAI95481.1 - 2.8e-10 40.5 0.0 7.8e-10 39.0 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 OAI95481.1 - 7.3e-10 39.0 0.2 1.7e-09 37.7 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 OAI95481.1 - 4.4e-09 35.6 0.0 2.2e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 OAI95481.1 - 9.1e-09 34.5 0.0 3.9e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein KR PF08659.5 OAI95481.1 - 0.00027 20.6 0.1 0.00064 19.4 0.1 1.7 1 1 1 2 2 2 1 KR domain NmrA PF05368.8 OAI95481.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family HypD PF01924.11 OAI95483.1 - 3.8e-141 469.9 0.0 4.3e-141 469.7 0.0 1.0 1 0 0 1 1 1 1 Hydrogenase formation hypA family MutS_III PF05192.13 OAI95509.1 - 3.2e-07 30.3 0.1 4e-07 30.0 0.1 1.1 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 OAI95509.1 - 3.3e-06 27.1 0.0 5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 MutS family domain IV Orthopox_F6 PF06601.7 OAI95509.1 - 0.051 13.5 0.1 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Orthopoxvirus F6 protein WXG100 PF06013.7 OAI95509.1 - 0.11 12.4 0.0 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF4537 PF15057.1 OAI95511.1 - 0.0072 16.1 0.1 0.041 13.6 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) GOLD_2 PF13897.1 OAI95511.1 - 0.04 14.1 0.0 0.049 13.8 0.0 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking NAD_binding_8 PF13450.1 OAI95518.1 - 1e-15 57.4 1.2 3.2e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 OAI95518.1 - 7.2e-07 28.6 0.0 8.5e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 OAI95518.1 - 1.2e-05 24.3 0.0 1.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAI95518.1 - 0.0015 17.4 0.1 0.0021 16.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAI95518.1 - 0.0053 16.6 0.0 0.17 11.7 0.0 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAI95518.1 - 0.0061 16.9 0.0 0.0099 16.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAI95518.1 - 0.042 12.3 0.0 0.057 11.8 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 OAI95518.1 - 0.063 12.3 0.1 0.098 11.7 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 OAI95518.1 - 0.068 13.2 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 OAI95518.1 - 0.14 11.4 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RadC PF04002.10 OAI95522.1 - 2.8e-43 146.5 0.0 5.1e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 RadC-like JAB domain Prok-JAB PF14464.1 OAI95522.1 - 0.00051 19.5 0.2 0.00081 18.9 0.1 1.5 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain Phage_integrase PF00589.17 OAI95537.1 - 0.00073 19.2 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF4431 PF14485.1 OAI95537.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) An_peroxidase PF03098.10 OAI95540.1 - 0.00049 18.6 0.0 0.00067 18.1 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase Septin PF00735.13 OAI95543.1 - 1e-08 34.5 0.0 1.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Septin MFS_1 PF07690.11 OAI95551.1 - 1.3e-10 40.5 3.2 1.4e-10 40.4 2.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAI95551.1 - 5e-05 22.0 0.6 5e-05 22.0 0.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 OAI95551.1 - 0.023 12.8 0.3 0.023 12.8 0.2 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector DUF2752 PF10825.3 OAI95551.1 - 0.2 11.6 1.6 0.33 10.9 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) NAD_binding_8 PF13450.1 OAI95552.1 - 6.5e-09 35.6 0.1 1.1e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 OAI95552.1 - 8.8e-06 24.9 0.1 1.2e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 OAI95552.1 - 1.4e-05 24.4 0.0 1.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 OAI95552.1 - 0.0001 21.3 0.0 0.00011 21.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAI95552.1 - 0.00012 21.0 0.4 0.00017 20.5 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 OAI95552.1 - 0.00055 19.0 0.6 0.00081 18.5 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 OAI95552.1 - 0.0041 15.6 1.1 0.0056 15.2 0.8 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 OAI95552.1 - 0.0056 17.0 0.9 0.01 16.2 0.6 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 OAI95552.1 - 0.0059 15.0 0.3 0.0082 14.5 0.2 1.1 1 0 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family Pyr_redox_2 PF07992.9 OAI95552.1 - 0.014 15.2 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 OAI95552.1 - 0.06 12.4 0.1 0.064 12.3 0.1 1.3 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 OAI95552.1 - 0.078 13.0 0.1 0.11 12.5 0.0 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase XhlA PF10779.4 OAI95560.1 - 0.18 11.7 6.0 0.19 11.6 3.9 1.3 1 1 0 1 1 1 0 Haemolysin XhlA DUF3616 PF12275.3 OAI95560.1 - 0.21 10.5 4.0 0.24 10.3 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) GMC_oxred_N PF00732.14 OAI95562.1 - 1.2e-27 96.9 0.0 1.5e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAI95562.1 - 8.3e-05 21.6 0.0 0.00022 20.2 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAI95562.1 - 0.00011 22.0 0.1 0.00031 20.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAI95562.1 - 0.00019 20.4 0.1 0.00028 19.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 OAI95562.1 - 0.0014 17.5 0.1 0.0024 16.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAI95562.1 - 0.016 15.0 0.1 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAI95562.1 - 0.028 13.4 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 OAI95562.1 - 0.042 13.6 0.1 0.075 12.7 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 OAI95562.1 - 0.11 12.5 0.2 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAI95562.1 - 0.16 10.4 0.0 0.23 9.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein MerR-DNA-bind PF09278.6 OAI95564.1 - 0.077 13.4 1.2 0.11 12.8 0.8 1.4 1 1 0 1 1 1 0 MerR, DNA binding PAS_9 PF13426.1 OAI95566.1 - 2.4e-12 47.1 0.0 4.2e-10 39.9 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 OAI95566.1 - 2.7e-12 46.4 0.0 5.7e-08 32.5 0.0 2.7 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.1 OAI95566.1 - 6e-11 41.7 0.1 1.9e-05 24.3 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 OAI95566.1 - 8.3e-11 41.9 0.1 3.1e-07 30.3 0.0 4.1 4 0 0 4 4 4 1 PAS fold GAF_2 PF13185.1 OAI95566.1 - 1.6e-07 31.9 0.1 2e-06 28.3 0.0 2.3 2 0 0 2 2 2 1 GAF domain PAS_3 PF08447.6 OAI95566.1 - 3.1e-06 27.2 0.0 8e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 PAS fold GAF PF01590.21 OAI95566.1 - 9.2e-06 25.8 0.1 1.8e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 OAI95566.1 - 0.006 16.6 1.0 0.073 13.1 0.0 2.8 3 0 0 3 3 3 1 GAF domain DUF1998 PF09369.5 OAI95566.1 - 0.1 13.1 0.0 19 5.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1998) PMSR PF01625.16 OAI95568.1 - 1.2e-31 109.6 0.0 1.6e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase zf-U1 PF06220.7 OAI95570.1 - 8e-16 57.3 3.4 1.2e-15 56.8 2.4 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 OAI95570.1 - 0.15 12.2 0.9 0.31 11.2 0.6 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAI95570.1 - 1.4 9.2 3.9 24 5.3 2.7 2.7 1 1 0 1 1 1 0 Zinc-finger of C2H2 type TPR_19 PF14559.1 OAI95573.1 - 4.6e-08 33.2 26.4 0.12 12.6 0.1 5.9 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 OAI95573.1 - 0.00023 21.0 15.9 0.0033 17.3 2.1 4.8 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 OAI95573.1 - 0.0029 17.8 31.0 0.81 10.3 0.4 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAI95573.1 - 0.038 14.6 39.2 1.2 10.0 1.5 8.0 5 3 3 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAI95573.1 - 0.042 14.3 17.6 0.32 11.5 0.1 6.0 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAI95573.1 - 0.045 13.5 2.3 26 4.9 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAI95573.1 - 0.063 13.1 23.1 6.8 6.7 0.1 6.9 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAI95573.1 - 0.094 12.3 1.9 27 4.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAI95573.1 - 0.19 11.7 13.5 13 5.9 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF4363 PF14276.1 OAI95573.1 - 0.32 10.7 4.2 0.67 9.6 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) TPR_17 PF13431.1 OAI95573.1 - 0.35 11.1 6.1 6.2 7.2 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAI95573.1 - 2.3 8.9 33.2 0.9 10.2 0.6 6.9 7 1 1 8 8 8 0 Tetratricopeptide repeat Acetyltransf_3 PF13302.1 OAI95575.1 - 1.4e-13 51.1 0.0 1.6e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAI95575.1 - 6.2e-06 26.1 0.0 1e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family AICARFT_IMPCHas PF01808.13 OAI95580.1 - 3.6e-09 36.1 0.0 4e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme RVT_2 PF07727.9 OAI95590.1 - 1e-20 73.7 0.0 1.4e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2CSK_N PF08521.5 OAI95590.1 - 0.04 13.4 0.0 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 Two-component sensor kinase N-terminal ICL PF00463.16 OAI95593.1 - 2.1e-97 326.5 0.1 1.1e-95 320.8 0.0 2.0 1 1 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 OAI95593.1 - 2e-10 40.2 0.0 4.2e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 OAI95593.1 - 0.0014 18.0 0.5 0.0032 16.8 0.0 1.8 2 0 0 2 2 2 1 Arginine repressor, C-terminal domain RVT_1 PF00078.22 OAI95600.1 - 8.5e-16 57.9 0.0 1.1e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ADH_N PF08240.7 OAI95601.1 - 0.0038 16.9 0.1 0.005 16.5 0.1 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF3558 PF12079.3 OAI95602.1 - 0.063 12.9 0.1 0.074 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) Phage_int_SAM_1 PF02899.12 OAI95609.1 - 0.0062 16.6 0.0 0.053 13.6 0.0 2.5 1 1 1 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.17 OAI95611.1 - 0.00052 19.7 0.0 0.0006 19.5 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family DUF4431 PF14485.1 OAI95611.1 - 0.013 15.0 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) Asn_synthase PF00733.16 OAI95616.1 - 3.8e-13 49.5 0.1 1.4e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 OAI95616.1 - 0.0044 15.9 0.0 0.0056 15.5 0.0 1.1 1 0 0 1 1 1 1 NAD synthase Ribosomal_60s PF00428.14 OAI95616.1 - 0.016 15.6 0.5 0.023 15.0 0.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein AalphaY_MDB PF04611.7 OAI95616.1 - 0.067 13.0 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region QueC PF06508.8 OAI95616.1 - 0.13 11.4 0.0 0.16 11.2 0.0 1.3 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC SR-25 PF10500.4 OAI95621.1 - 0.0079 15.6 21.3 0.014 14.8 14.8 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Autoind_bind PF03472.10 OAI95621.1 - 0.066 12.5 0.2 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Autoinducer binding domain TFIIA PF03153.8 OAI95623.1 - 0.32 10.8 2.3 0.52 10.1 1.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S19 PF00203.16 OAI95626.1 - 7.1e-32 108.8 0.2 1e-31 108.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 OAI95626.1 - 0.033 14.0 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein FliH DSHCT PF08148.7 OAI95629.1 - 7.8e-17 61.0 0.1 1.8e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain CCDC92 PF14916.1 OAI95629.1 - 0.059 12.9 0.4 0.13 11.8 0.1 1.7 1 1 0 1 1 1 0 Coiled-coil domain of unknown function 6PGD PF00393.14 OAI95631.1 - 4.7e-05 22.7 0.0 5.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain PDZ_2 PF13180.1 OAI95634.1 - 0.00039 20.2 0.0 0.00052 19.8 0.0 1.2 1 0 0 1 1 1 1 PDZ domain DUF3394 PF11874.3 OAI95634.1 - 0.041 13.4 0.0 0.051 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) PDZ PF00595.19 OAI95634.1 - 0.048 13.8 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) PAS_4 PF08448.5 OAI95642.1 - 5.8e-20 71.3 1.2 3.9e-09 36.5 0.0 4.4 4 1 0 4 4 4 3 PAS fold PAS_9 PF13426.1 OAI95642.1 - 1.3e-11 44.7 0.0 0.052 13.9 0.0 4.3 4 0 0 4 4 4 3 PAS domain PAS_8 PF13188.1 OAI95642.1 - 5.3e-10 38.7 0.4 0.0015 18.3 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS PF00989.19 OAI95642.1 - 9.2e-10 38.3 0.1 0.0012 18.6 0.0 3.9 3 1 0 3 3 3 2 PAS fold PAS_3 PF08447.6 OAI95642.1 - 5.3e-08 32.8 0.0 0.0022 18.0 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_7 PF12860.2 OAI95642.1 - 8.2e-06 25.8 0.3 0.71 9.9 0.1 3.8 3 1 0 3 3 3 2 PAS fold PAS_10 PF13596.1 OAI95642.1 - 0.16 12.2 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 PAS domain Cytochrome_CBB3 PF13442.1 OAI95643.1 - 1.4e-14 54.0 0.0 2.2e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 OAI95643.1 - 1.7e-06 28.7 0.1 5.3e-06 27.1 0.1 1.8 1 1 0 1 1 1 1 Cytochrome c DUF1952 PF09189.5 OAI95645.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) Pro_isomerase PF00160.16 OAI95649.1 - 1.6e-47 161.5 0.7 1.9e-47 161.3 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RecO_N PF11967.3 OAI95661.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Recombination protein O N terminal AMP-binding PF00501.23 OAI95665.1 - 4.4e-51 173.5 0.0 5e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme RVT_1 PF00078.22 OAI95676.1 - 0.0042 16.4 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sel1 PF08238.7 OAI95679.1 - 1.2e-05 25.7 12.9 0.15 12.7 0.0 6.0 7 0 0 7 7 7 2 Sel1 repeat TPR_16 PF13432.1 OAI95679.1 - 0.011 16.4 1.6 0.28 11.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2587 PF10759.4 OAI95679.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) TPR_2 PF07719.12 OAI95679.1 - 0.042 13.7 1.7 0.31 11.0 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat cEGF PF12662.2 OAI95681.1 - 0.036 13.6 80.4 0.12 12.0 0.4 12.5 13 0 0 13 13 13 0 Complement Clr-like EGF-like CHASE PF03924.8 OAI95684.1 - 4.2e-55 185.9 0.3 5.5e-55 185.5 0.2 1.1 1 0 0 1 1 1 1 CHASE domain Glyoxalase PF00903.20 OAI95687.1 - 1.3e-10 41.3 1.2 4.2e-08 33.2 0.2 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short_C2 PF13561.1 OAI95687.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase IGF2_C PF08365.6 OAI95689.1 - 0.028 14.1 0.2 5.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide DUF1325 PF07039.6 OAI95691.1 - 1e-10 41.3 0.0 1.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain HDV_ag PF01517.13 OAI95691.1 - 0.013 15.1 0.3 0.028 14.1 0.0 1.6 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen Chorion_2 PF03964.10 OAI95691.1 - 1.5 9.4 7.8 0.45 11.0 1.7 2.4 2 1 0 2 2 2 0 Chorion family 2 IstB_IS21 PF01695.12 OAI95697.1 - 3.7e-36 124.2 0.0 7.1e-36 123.2 0.0 1.5 2 0 0 2 2 2 1 IstB-like ATP binding protein rve PF00665.21 OAI95697.1 - 7.1e-11 42.2 0.0 1.3e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain PhoH PF02562.11 OAI95697.1 - 1.6e-06 27.4 0.0 8.2e-06 25.1 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein ArgK PF03308.11 OAI95697.1 - 8.8e-05 21.4 0.0 0.00014 20.7 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA PF00004.24 OAI95697.1 - 0.0005 20.2 0.0 0.00094 19.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 OAI95697.1 - 0.0012 18.3 0.2 0.004 16.5 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 OAI95697.1 - 0.0015 18.2 0.1 0.0059 16.3 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain rve_3 PF13683.1 OAI95697.1 - 0.0032 16.9 0.1 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Sigma54_activ_2 PF14532.1 OAI95697.1 - 0.0083 16.1 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 OAI95697.1 - 0.011 15.7 1.3 0.062 13.2 0.1 2.4 1 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 OAI95697.1 - 0.013 15.4 0.2 0.05 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 OAI95697.1 - 0.023 15.5 0.4 0.084 13.6 0.0 2.2 3 0 0 3 3 1 0 AAA domain KaiC PF06745.8 OAI95697.1 - 0.037 13.1 0.0 0.073 12.1 0.0 1.4 1 0 0 1 1 1 0 KaiC Bac_DnaA PF00308.13 OAI95697.1 - 0.061 12.9 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Bacterial dnaA protein ABC_tran PF00005.22 OAI95697.1 - 0.067 13.4 0.0 0.3 11.3 0.0 2.1 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 OAI95697.1 - 0.084 13.0 0.1 0.68 10.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 OAI95697.1 - 0.16 11.5 0.1 0.85 9.1 0.1 1.9 1 1 1 2 2 2 0 AAA domain KTI12 PF08433.5 OAI95697.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF258 PF03193.11 OAI95697.1 - 0.21 10.7 0.0 0.4 9.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Phage_integrase PF00589.17 OAI95702.1 - 0.004 16.8 0.0 0.0058 16.3 0.0 1.4 1 1 0 1 1 1 1 Phage integrase family Rib_5-P_isom_A PF06026.9 OAI95708.1 - 1.1e-54 184.3 0.0 1.2e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) MarR_2 PF12802.2 OAI95709.1 - 2.1e-07 30.4 1.6 2.9e-07 30.0 0.3 1.8 2 1 0 2 2 2 1 MarR family MarR PF01047.17 OAI95709.1 - 6.6e-06 25.7 0.0 1.4e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.1 OAI95709.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain DUF605 PF04652.11 OAI95714.1 - 7 5.9 18.6 7.9 5.7 12.9 1.1 1 0 0 1 1 1 0 Vta1 like CorA PF01544.13 OAI95716.1 - 1.2e-32 113.1 0.0 1.5e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein GST_N PF02798.15 OAI95716.1 - 3.2e-10 40.0 0.0 7.7e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAI95716.1 - 1.2e-07 31.6 0.0 2.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 OAI95716.1 - 5.9e-07 29.6 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 OAI95716.1 - 2.8e-05 24.5 0.1 0.00026 21.4 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAI95716.1 - 8.8e-05 22.4 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAI95716.1 - 0.0014 18.4 0.4 0.0063 16.3 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Helicase_C PF00271.26 OAI95717.1 - 2.3e-09 36.9 0.0 6.6e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain NgoMIV_restric PF09015.5 OAI95717.1 - 0.04 12.9 0.3 0.055 12.4 0.2 1.2 1 0 0 1 1 1 0 NgoMIV restriction enzyme FokI_N PF02981.10 OAI95717.1 - 0.12 12.0 0.0 0.38 10.3 0.0 1.7 2 0 0 2 2 2 0 Restriction endonuclease FokI, recognition domain rve PF00665.21 OAI95719.1 - 4.3e-18 65.5 0.0 6.5e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAI95719.1 - 0.00031 20.2 0.0 0.00079 18.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Abhydrolase_6 PF12697.2 OAI95720.1 - 2.1e-14 53.9 0.1 2.3e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 OAI95720.1 - 9.9e-06 25.3 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 OAI95720.1 - 0.00065 19.3 0.0 0.0007 19.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAI95720.1 - 0.023 14.4 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family UBA PF00627.26 OAI95724.1 - 0.004 16.9 0.0 0.0082 15.9 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain HrpB1_HrpK PF09613.5 OAI95724.1 - 4.2 6.8 5.5 0.58 9.6 0.1 2.2 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Glycos_transf_2 PF00535.21 OAI95729.1 - 4.1e-31 107.9 0.0 6e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 OAI95729.1 - 4.9e-12 46.1 0.0 7.4e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 OAI95729.1 - 0.00059 20.1 0.0 0.0053 17.0 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 2 Pkinase PF00069.20 OAI95735.1 - 4.3e-23 81.7 0.0 4.9e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI95735.1 - 6.3e-14 51.6 0.0 8.8e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI95735.1 - 0.00013 21.0 0.0 0.00017 20.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAI95735.1 - 0.066 12.9 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family U3snoRNP10 PF12397.3 OAI95737.1 - 6.3e-06 26.1 1.0 2e-05 24.5 0.7 1.9 1 1 0 1 1 1 1 U3 small nucleolar RNA-associated protein 10 HTH_Tnp_4 PF13613.1 OAI95742.1 - 0.00023 20.6 0.0 0.00048 19.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 OAI95742.1 - 0.001 18.6 0.3 0.0026 17.3 0.0 1.8 2 0 0 2 2 1 1 Homeodomain-like domain MarR_2 PF12802.2 OAI95742.1 - 0.0016 18.0 0.0 0.0039 16.8 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.1 OAI95742.1 - 0.0027 17.4 0.0 0.0072 16.0 0.0 1.8 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_28 PF13518.1 OAI95742.1 - 0.0029 17.5 0.3 0.012 15.5 0.0 2.2 2 1 1 3 3 3 1 Helix-turn-helix domain MarR PF01047.17 OAI95742.1 - 0.005 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 MarR family CENP-B_N PF04218.8 OAI95742.1 - 0.0075 15.6 0.0 0.02 14.3 0.0 1.7 1 1 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_29 PF13551.1 OAI95742.1 - 0.013 15.5 0.4 0.026 14.6 0.3 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_38 PF13936.1 OAI95742.1 - 0.024 14.1 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 OAI95742.1 - 0.054 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.11 OAI95742.1 - 0.071 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_IclR PF09339.5 OAI95742.1 - 0.081 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain Crp PF00325.15 OAI95742.1 - 0.081 12.4 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family HTH_Tnp_IS630 PF01710.11 OAI95742.1 - 0.086 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Transposase RVT_1 PF00078.22 OAI95749.1 - 0.0076 15.6 0.0 0.0087 15.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2514 PF10721.4 OAI95753.1 - 0.11 12.2 2.1 0.19 11.4 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Mur_ligase_C PF02875.16 OAI95757.1 - 0.043 13.8 0.1 0.73 9.9 0.0 2.5 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain PTS_EIIA_2 PF00359.17 OAI95761.1 - 6e-18 64.9 0.5 1e-13 51.2 0.0 2.3 1 1 1 2 2 2 2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 GrpE PF01025.14 OAI95762.1 - 2.3e-48 163.8 0.1 2.6e-48 163.6 0.1 1.0 1 0 0 1 1 1 1 GrpE Rep_3 PF01051.16 OAI95768.1 - 5.1e-25 88.3 0.0 6.1e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 Initiator Replication protein WXG100 PF06013.7 OAI95768.1 - 0.045 13.7 0.1 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG ECH PF00378.15 OAI95771.1 - 5.1e-13 48.7 0.7 6e-13 48.4 0.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Clathrin_H_link PF13838.1 OAI95772.1 - 2.7e-28 97.6 0.0 4.1e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Clathrin-H-link Pyr_redox_3 PF13738.1 OAI95774.1 - 7.9e-23 81.5 0.0 1.2e-22 80.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAI95774.1 - 1.4e-10 40.0 0.0 2.3e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAI95774.1 - 7.5e-09 34.9 0.0 1.2e-08 34.2 0.0 1.3 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAI95774.1 - 5.6e-05 23.1 0.0 0.00021 21.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAI95774.1 - 0.056 13.2 0.5 0.98 9.1 0.0 2.7 2 1 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 OAI95774.1 - 0.064 11.7 0.0 0.15 10.5 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_2 PF03446.10 OAI95774.1 - 0.078 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 OAI95774.1 - 0.079 12.1 0.0 0.18 10.9 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UBN2 PF14223.1 OAI95782.1 - 6.2e-15 55.0 0.1 1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAI95782.1 - 3.3e-14 52.4 0.0 4.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 OAI95782.1 - 2.7e-05 23.4 2.9 0.0001 21.6 0.1 3.0 3 1 1 4 4 4 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 OAI95782.1 - 8.7e-05 22.1 0.1 0.00021 20.9 0.0 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type eIF3g PF12353.3 OAI95782.1 - 0.0053 16.6 1.2 0.011 15.7 0.8 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G GH97_C PF14509.1 OAI95785.1 - 3.1e-32 110.7 0.1 3.9e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl-hydrolase 97 C-terminal, oligomerisation Glyco_hydro_97 PF10566.4 OAI95785.1 - 1.1e-13 50.9 0.0 1.6e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 97 MFS_1 PF07690.11 OAI95786.1 - 2.4e-11 42.9 15.9 3.1e-11 42.6 11.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF914 PF06027.7 OAI95786.1 - 0.1 11.4 4.3 0.17 10.6 3.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) DUF2231 PF09990.4 OAI95786.1 - 0.13 12.5 0.0 0.13 12.5 0.0 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) VEK-30 PF12107.3 OAI95786.1 - 0.24 11.1 0.5 0.53 10.0 0.4 1.5 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway DUF1129 PF06570.6 OAI95786.1 - 3.9 6.7 9.3 0.59 9.3 1.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Cytochrom_B_N PF00033.14 OAI95786.1 - 5.4 6.3 9.5 1e+02 2.1 6.6 2.6 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Chorismate_synt PF01264.16 OAI95788.1 - 3.5e-122 407.2 0.1 5.9e-122 406.4 0.1 1.3 1 1 0 1 1 1 1 Chorismate synthase Gag_spuma PF03276.9 OAI95802.1 - 0.034 12.4 4.5 0.042 12.1 3.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Cwf_Cwc_15 PF04889.7 OAI95802.1 - 0.051 13.2 15.2 0.079 12.6 10.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM60A PF15396.1 OAI95802.1 - 0.068 12.9 9.4 0.088 12.5 6.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Pox_Ag35 PF03286.9 OAI95802.1 - 0.23 10.9 16.2 0.31 10.5 11.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ustilago_mating PF05722.7 OAI95802.1 - 0.23 10.7 12.0 0.3 10.3 8.3 1.1 1 0 0 1 1 1 0 Ustilago B locus mating-type protein DUF2217 PF10265.4 OAI95802.1 - 0.62 8.7 6.5 0.61 8.7 4.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DNA_pol_viral_N PF00242.12 OAI95802.1 - 0.63 9.0 10.3 0.71 8.8 7.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Neur_chan_memb PF02932.11 OAI95802.1 - 2.6 7.8 4.8 2.8 7.7 3.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ebola_NP PF05505.7 OAI95802.1 - 4.6 5.1 10.5 4.8 5.1 7.3 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Hid1 PF12722.2 OAI95802.1 - 4.7 4.7 7.8 4.7 4.7 5.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FancD2 PF14631.1 OAI95802.1 - 5.5 3.9 6.6 5.8 3.8 4.6 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF1510 PF07423.6 OAI95802.1 - 5.6 6.2 13.7 7.7 5.8 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Presenilin PF01080.12 OAI95802.1 - 5.9 5.6 6.4 6.9 5.3 4.5 1.2 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.8 OAI95802.1 - 6.4 5.1 15.2 8.2 4.8 10.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 LysR_substrate PF03466.15 OAI95811.1 - 3.2e-50 170.1 1.5 5.8e-50 169.2 1.0 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.22 OAI95811.1 - 2.5e-21 75.1 3.5 8.4e-21 73.4 2.5 2.0 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.2 OAI95811.1 - 4.4e-05 22.5 0.0 0.0005 19.0 0.0 2.1 2 0 0 2 2 2 1 PBP superfamily domain HTH_20 PF12840.2 OAI95811.1 - 0.00036 20.2 0.9 0.0032 17.2 0.2 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain MarR_2 PF12802.2 OAI95811.1 - 0.00056 19.5 0.5 0.0022 17.6 0.4 2.1 1 0 0 1 1 1 1 MarR family HTH_30 PF13556.1 OAI95811.1 - 0.0007 19.1 0.2 0.0016 18.0 0.1 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain MarR PF01047.17 OAI95811.1 - 0.0016 18.1 0.2 0.042 13.5 0.1 2.7 2 0 0 2 2 2 1 MarR family HTH_5 PF01022.15 OAI95811.1 - 0.013 15.1 0.0 0.033 13.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 OAI95811.1 - 0.02 14.3 0.2 0.048 13.0 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.1 OAI95811.1 - 0.047 13.3 0.1 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_AsnC-type PF13404.1 OAI95811.1 - 0.23 11.0 0.1 0.23 11.0 0.1 2.6 4 0 0 4 4 4 0 AsnC-type helix-turn-helix domain Cellulase PF00150.13 OAI95828.1 - 0.066 12.4 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) DUF417 PF04224.7 OAI95830.1 - 2.1e-18 66.2 6.4 8.6e-17 61.0 4.4 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF417 DoxX_2 PF13564.1 OAI95830.1 - 0.068 13.1 7.0 0.12 12.3 4.9 1.7 1 1 0 1 1 1 0 DoxX-like family DoxX PF07681.7 OAI95830.1 - 2 8.9 9.9 0.42 11.0 3.0 2.0 1 1 1 2 2 2 0 DoxX Resolvase PF00239.16 OAI95831.1 - 1.3e-34 119.0 0.0 1.5e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Resolvase, N terminal domain DsrH PF04077.7 OAI95831.1 - 0.098 12.3 0.2 6.3 6.5 0.0 2.5 2 1 1 3 3 3 0 DsrH like protein RVT_2 PF07727.9 OAI95835.1 - 1.8e-48 164.6 0.0 2.3e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RuvC PF02075.12 OAI95835.1 - 0.11 12.3 0.0 0.79 9.5 0.0 2.2 2 0 0 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC ABC2_membrane PF01061.19 OAI95836.1 - 1.6e-44 151.5 22.2 1.6e-44 151.5 15.4 1.4 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.7 OAI95836.1 - 3.7e-19 68.2 3.6 9.4e-19 66.9 0.0 2.5 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_2 PF12679.2 OAI95836.1 - 9.4e-07 27.9 0.3 2.8e-06 26.3 0.2 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.2 OAI95836.1 - 0.00035 19.7 30.6 0.00054 19.0 15.5 3.0 2 1 0 2 2 2 1 ABC-2 family transporter protein rve PF00665.21 OAI95839.1 - 1.4e-18 67.1 0.0 2.2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAI95839.1 - 0.008 15.6 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain GFA PF04828.9 OAI95841.1 - 1.3e-18 66.7 0.8 2.3e-18 65.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.1 OAI95841.1 - 2.4 8.5 5.6 22 5.4 1.4 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar SBP_bac_3 PF00497.15 OAI95850.1 - 7.9e-24 84.1 0.0 1.1e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 PAS_4 PF08448.5 OAI95850.1 - 1.3e-20 73.4 0.1 4.4e-20 71.7 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 OAI95850.1 - 1.4e-08 34.9 0.1 3.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.1 OAI95850.1 - 6.7e-05 22.5 0.0 0.00022 20.9 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 OAI95850.1 - 0.00018 21.2 0.0 0.00036 20.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold NMT1 PF09084.6 OAI95850.1 - 0.0084 15.7 0.0 0.03 13.9 0.0 1.7 2 0 0 2 2 2 1 NMT1/THI5 like DUF4149 PF13664.1 OAI95850.1 - 0.036 14.1 0.1 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF4332 PF14229.1 OAI95854.1 - 0.048 13.6 0.1 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) RadC PF04002.10 OAI95855.1 - 2.7e-34 117.4 0.0 4.8e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 RadC-like JAB domain MarR_2 PF12802.2 OAI95855.1 - 0.00024 20.7 0.0 0.00071 19.2 0.0 1.9 1 0 0 1 1 1 1 MarR family Prok-JAB PF14464.1 OAI95855.1 - 0.00024 20.6 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain HTH_27 PF13463.1 OAI95855.1 - 0.00098 19.4 0.1 0.012 15.8 0.0 2.5 3 0 0 3 3 3 1 Winged helix DNA-binding domain HTH_IclR PF09339.5 OAI95855.1 - 0.018 14.5 0.2 0.057 13.0 0.0 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain Toxin-JAB1 PF15659.1 OAI95855.1 - 0.019 14.8 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 JAB-like toxin 1 MarR PF01047.17 OAI95855.1 - 0.056 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.1 OAI95855.1 - 0.068 12.5 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Asp_protease_2 PF13650.1 OAI95856.1 - 7.4e-05 23.1 0.1 0.00018 21.9 0.1 1.8 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI95856.1 - 0.00033 20.5 0.0 0.00093 19.0 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI95856.1 - 0.0071 16.1 0.1 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.21 OAI95868.1 - 7.8e-06 25.9 0.3 1.6e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain TMF_DNA_bd PF12329.3 OAI95870.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Retrotrans_gag PF03732.12 OAI95870.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein FAP PF07174.6 OAI95870.1 - 4.3 6.5 21.1 0.98 8.6 4.0 2.2 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Acyl_transf_1 PF00698.16 OAI95877.1 - 3.2e-54 184.4 0.9 3.6e-54 184.2 0.1 1.4 2 0 0 2 2 2 1 Acyl transferase domain MaoC_dehydratas PF01575.14 OAI95877.1 - 5e-29 100.1 0.0 1.6e-28 98.5 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain HbrB PF08539.6 OAI95877.1 - 0.2 11.4 2.2 0.76 9.6 0.0 2.2 2 0 0 2 2 2 0 HbrB-like Pec_lyase_C PF00544.14 OAI95881.1 - 4.3e-53 179.7 3.8 6.1e-53 179.2 2.7 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 OAI95881.1 - 3.6e-05 23.5 25.3 0.0017 18.1 8.7 2.7 1 1 1 2 2 2 2 Right handed beta helix region TMEM171 PF15471.1 OAI95884.1 - 0.31 9.7 1.5 0.55 8.9 1.0 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Resolvase PF00239.16 OAI95899.1 - 4.6e-13 49.2 0.0 4.8e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 Resolvase, N terminal domain Phage_integrase PF00589.17 OAI95902.1 - 5.8e-06 26.0 0.0 7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family OCD_Mu_crystall PF02423.10 OAI95903.1 - 2.5e-32 111.9 0.0 3.1e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 OAI95903.1 - 0.0034 17.4 0.0 0.0065 16.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 OAI95903.1 - 0.038 14.4 0.0 0.081 13.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RVT_3 PF13456.1 OAI95905.1 - 0.011 15.5 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase-like DNA_pol_viral_C PF00336.13 OAI95905.1 - 0.02 14.1 0.3 0.047 12.9 0.0 1.6 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain rve PF00665.21 OAI95908.1 - 3.9e-13 49.5 0.0 9.7e-13 48.2 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Thioredoxin_4 PF13462.1 OAI95919.1 - 6.2e-23 81.5 0.0 7.9e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 OAI95919.1 - 1.4e-16 60.5 1.1 1.9e-14 53.6 0.8 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 OAI95919.1 - 3.7e-06 27.0 0.2 1.3e-05 25.3 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 OAI95919.1 - 0.0001 22.0 0.0 0.33 10.7 0.0 2.7 2 1 0 2 2 2 2 Thioredoxin domain Thioredoxin PF00085.15 OAI95919.1 - 0.0019 17.8 0.0 0.0051 16.4 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 OAI95919.1 - 0.0073 15.8 0.1 0.3 10.6 0.0 2.2 2 0 0 2 2 2 1 Redoxin Thioredoxin_8 PF13905.1 OAI95919.1 - 0.016 15.3 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like HTH_38 PF13936.1 OAI95919.1 - 0.096 12.2 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain TFIIF_alpha PF05793.7 OAI95919.1 - 0.14 10.4 0.1 0.18 10.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AhpC-TSA PF00578.16 OAI95919.1 - 0.15 11.7 0.0 1.4 8.6 0.0 2.0 2 0 0 2 2 2 0 AhpC/TSA family S4_2 PF13275.1 OAI95922.1 - 0.032 13.8 0.1 0.05 13.1 0.1 1.3 1 0 0 1 1 1 0 S4 domain FHA PF00498.21 OAI95922.1 - 0.074 13.1 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 FHA domain DUF417 PF04224.7 OAI95928.1 - 3.9e-19 68.6 0.7 4.4e-19 68.5 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF417 DoxX PF07681.7 OAI95928.1 - 0.79 10.1 9.1 0.17 12.2 3.2 1.9 1 1 1 2 2 2 0 DoxX MarR_2 PF12802.2 OAI95929.1 - 2.8e-10 39.6 1.2 9.3e-10 38.0 0.1 2.2 2 1 0 2 2 2 1 MarR family MarR PF01047.17 OAI95929.1 - 3.3e-08 33.0 0.0 7.5e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 OAI95929.1 - 2.8e-07 30.7 0.1 7.5e-07 29.3 0.1 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain Ftsk_gamma PF09397.5 OAI95929.1 - 0.00026 20.6 0.1 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 Ftsk gamma domain HTH_29 PF13551.1 OAI95929.1 - 0.0075 16.3 0.1 0.017 15.2 0.1 1.7 1 1 1 2 2 2 1 Winged helix-turn helix TrmB PF01978.14 OAI95929.1 - 0.023 14.3 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 OAI95929.1 - 0.07 12.5 0.0 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding p450 PF00067.17 OAI95934.1 - 1.6e-35 122.5 0.0 2.1e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rtf2 PF04641.7 OAI95945.1 - 0.1 11.7 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Retrotrans_gag PF03732.12 OAI95951.1 - 0.11 12.5 0.1 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein Autotransporter PF03797.14 OAI95956.1 - 4.1e-37 127.9 7.6 6.2e-37 127.3 5.3 1.2 1 0 0 1 1 1 1 Autotransporter beta-domain Peptidase_M28 PF04389.12 OAI95956.1 - 0.01 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M28 DDE_Tnp_Tn3 PF01526.12 OAI95962.1 - 9.2e-130 432.7 0.0 1e-129 432.5 0.0 1.0 1 0 0 1 1 1 1 Tn3 transposase DDE domain Totivirus_coat PF05518.6 OAI95972.1 - 1.7 6.3 5.0 2 6.1 3.5 1.0 1 0 0 1 1 1 0 Totivirus coat protein rve PF00665.21 OAI95973.1 - 6.4e-12 45.6 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain GntR PF00392.16 OAI95973.1 - 0.084 12.3 0.1 0.35 10.3 0.1 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family rve_3 PF13683.1 OAI95973.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain PID PF00640.18 OAI95976.1 - 0.089 12.7 0.1 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) TauE PF01925.14 OAI95981.1 - 1.3e-11 44.4 9.7 1.5e-11 44.2 6.7 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE ThiW PF09512.5 OAI95981.1 - 0.032 14.0 3.3 0.04 13.7 2.3 1.3 1 0 0 1 1 1 0 Thiamine-precursor transporter protein (ThiW) DUF3169 PF11368.3 OAI95981.1 - 0.11 11.6 1.3 0.14 11.3 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF2232 PF09991.4 OAI95981.1 - 0.19 10.6 4.4 0.21 10.5 3.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DoxX_3 PF13781.1 OAI95981.1 - 0.21 11.9 4.4 0.28 11.5 3.0 1.2 1 0 0 1 1 1 0 DoxX-like family Thioredoxin_2 PF13098.1 OAI95982.1 - 5.1e-14 52.4 0.0 9.7e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 OAI95982.1 - 5.5e-07 29.7 0.0 4e-06 26.9 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin DSBA PF01323.15 OAI95982.1 - 0.00048 19.7 0.5 0.099 12.1 0.2 2.6 2 1 0 2 2 2 2 DSBA-like thioredoxin domain DsbC_N PF10411.4 OAI95982.1 - 0.0024 17.0 0.0 0.0056 15.9 0.0 1.6 1 0 0 1 1 1 1 Disulfide bond isomerase protein N-terminus PepSY_2 PF13670.1 OAI95982.1 - 0.043 13.7 0.7 0.69 9.8 0.0 2.5 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain Thioredoxin_3 PF13192.1 OAI95982.1 - 0.13 12.1 0.0 8.5 6.2 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin domain MCPsignal PF00015.16 OAI95987.1 - 5.6e-17 62.0 5.4 8.4e-17 61.4 3.8 1.4 1 1 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain ArdA PF07275.6 OAI95987.1 - 0.0073 16.5 0.0 0.0092 16.2 0.0 1.2 1 0 0 1 1 1 1 Antirestriction protein (ArdA) EamA PF00892.15 OAI95988.1 - 1.8e-13 50.6 3.7 1.8e-13 50.6 2.6 2.3 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 OAI95988.1 - 3.5e-08 33.6 4.7 3.5e-08 33.6 3.2 2.2 2 0 0 2 2 2 1 Multidrug resistance efflux transporter DUF914 PF06027.7 OAI95988.1 - 0.00013 20.9 1.6 0.0002 20.3 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) Nuc_sug_transp PF04142.10 OAI95988.1 - 0.044 12.8 0.8 0.063 12.3 0.6 1.3 1 0 0 1 1 1 0 Nucleotide-sugar transporter CreD PF06123.7 OAI95988.1 - 0.25 9.8 3.7 0.33 9.4 2.6 1.1 1 0 0 1 1 1 0 Inner membrane protein CreD RAP1 PF07218.6 OAI95993.1 - 0.35 8.9 6.2 0.42 8.6 4.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF572 PF04502.8 OAI95993.1 - 0.88 8.7 16.2 1.2 8.2 11.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Spt5-NGN PF03439.8 OAI96005.1 - 7.7e-20 70.4 0.0 1.6e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 OAI96005.1 - 2.5e-09 37.6 5.8 2.5e-09 37.6 4.0 2.9 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 OAI96005.1 - 0.0066 16.1 10.0 0.61 9.9 0.4 3.7 3 0 0 3 3 3 2 KOW motif DUF2457 PF10446.4 OAI96005.1 - 0.44 9.2 19.0 0.86 8.2 13.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 OAI96005.1 - 5.3 5.4 12.2 1.2 7.5 5.8 1.7 2 0 0 2 2 2 0 Daxx Family SDA1 PF05285.7 OAI96005.1 - 8.3 5.5 15.2 17 4.5 10.6 1.5 1 0 0 1 1 1 0 SDA1 His_Phos_1 PF00300.17 OAI96016.1 - 2.8e-06 27.5 0.0 3.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Vps16_N PF04841.8 OAI96020.1 - 0.0002 20.0 0.0 0.00021 19.9 0.0 1.0 1 0 0 1 1 1 1 Vps16, N-terminal region HSBP1 PF06825.7 OAI96021.1 - 5.5e-11 41.8 0.1 7.9e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Helicase_C PF00271.26 OAI96022.1 - 6.3e-07 29.1 0.1 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 OAI96022.1 - 7e-05 22.1 0.2 9.2e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain DUF3516 PF12029.3 OAI96022.1 - 0.042 12.6 0.2 0.061 12.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) DUF3573 PF12097.3 OAI96022.1 - 0.15 10.6 0.2 0.21 10.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DEDD_Tnp_IS110 PF01548.12 OAI96024.1 - 2.7e-27 95.2 0.3 9.6e-27 93.4 0.0 1.9 2 0 0 2 2 2 1 Transposase Transposase_20 PF02371.11 OAI96024.1 - 5.7e-25 87.2 0.1 1.4e-24 85.9 0.1 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family TSCPD PF12637.2 OAI96024.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 TSCPD domain FHA PF00498.21 OAI96027.1 - 0.0099 15.9 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain Retrotrans_gag PF03732.12 OAI96032.1 - 2.1e-05 24.4 0.1 6.7e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Herpes_US9 PF06072.6 OAI96037.1 - 0.079 12.8 0.6 0.15 11.9 0.4 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 UPF0149 PF03695.8 OAI96039.1 - 4.8e-31 108.0 3.4 5.6e-31 107.7 2.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0149) SEC-C PF02810.10 OAI96039.1 - 1.9e-10 40.0 6.9 2.8e-10 39.4 4.8 1.3 1 0 0 1 1 1 1 SEC-C motif AAA_4 PF04326.9 OAI96040.1 - 9.5e-12 45.1 0.0 2.2e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Divergent AAA domain LysR_substrate PF03466.15 OAI96043.1 - 1.7e-08 33.8 0.0 1.9e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 LysR substrate binding domain LysR_substrate PF03466.15 OAI96044.1 - 1.5e-23 82.9 4.8 2.6e-23 82.2 3.3 1.3 1 1 0 1 1 1 1 LysR substrate binding domain BTP PF05232.7 OAI96050.1 - 0.017 14.8 1.0 0.024 14.3 0.7 1.3 1 0 0 1 1 1 0 Bacterial Transmembrane Pair family DUF3180 PF11377.3 OAI96050.1 - 0.1 12.4 2.8 0.16 11.8 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3180) Isochorismatase PF00857.15 OAI96052.1 - 3e-32 111.9 0.2 3.8e-32 111.6 0.2 1.1 1 0 0 1 1 1 1 Isochorismatase family DDE_Tnp_IS1595 PF12762.2 OAI96052.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 ISXO2-like transposase domain COX3 PF00510.13 OAI96054.1 - 3.2e-21 75.9 8.8 4e-21 75.6 6.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III Voltage_CLC PF00654.15 OAI96056.1 - 1.4e-50 172.3 25.1 1.4e-50 172.3 17.4 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel HTH_Tnp_1 PF01527.15 OAI96057.1 - 3.9e-18 65.1 0.0 4.5e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.1 OAI96057.1 - 8.2e-06 25.7 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 OAI96057.1 - 5.3e-05 22.7 0.1 0.00012 21.5 0.0 1.6 1 1 1 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 OAI96057.1 - 0.00031 20.8 0.0 0.0004 20.5 0.0 1.3 1 1 0 1 1 1 1 Winged helix-turn helix Phage_CI_repr PF07022.8 OAI96057.1 - 0.0036 17.3 0.1 0.74 9.9 0.0 2.7 2 1 1 3 3 3 1 Bacteriophage CI repressor helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 OAI96057.1 - 0.006 15.7 0.0 0.016 14.3 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_7 PF02796.10 OAI96057.1 - 0.011 15.6 0.1 0.04 13.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_26 PF13443.1 OAI96057.1 - 0.047 13.9 0.0 0.14 12.3 0.0 1.8 1 1 1 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_Tnp_IS630 PF01710.11 OAI96057.1 - 0.049 13.2 0.0 0.055 13.1 0.0 1.1 1 0 0 1 1 1 0 Transposase BcrAD_BadFG PF01869.15 OAI96062.1 - 4.1e-25 88.5 1.2 4.6e-25 88.4 0.8 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Lambda_CIII PF02061.11 OAI96062.1 - 0.022 14.7 0.5 0.76 9.8 0.0 2.5 2 0 0 2 2 2 0 Lambda Phage CIII FGGY_N PF00370.16 OAI96062.1 - 0.031 13.6 0.0 0.41 9.9 0.0 2.1 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain DUF1289 PF06945.8 OAI96065.1 - 0.12 11.8 0.2 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) UPF0515 PF15135.1 OAI96069.1 - 0.014 14.5 0.1 0.014 14.4 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 HGTP_anticodon PF03129.15 OAI96069.1 - 0.049 13.5 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 Anticodon binding domain HupE_UreJ_2 PF13795.1 OAI96072.1 - 2e-49 166.9 9.5 2.6e-49 166.5 6.6 1.1 1 0 0 1 1 1 1 HupE / UreJ protein DUF872 PF05915.7 OAI96072.1 - 3.6 7.4 7.7 0.18 11.6 0.4 2.3 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) PIF1 PF05970.9 OAI96076.1 - 0.0059 15.6 0.0 0.0085 15.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Torsin PF06309.6 OAI96076.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Torsin DUF4158 PF13700.1 OAI96088.1 - 4.1e-42 143.4 1.2 4.1e-42 143.4 0.9 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4158) SpoIID PF08486.5 OAI96100.1 - 1.7 8.9 6.6 3.9 7.7 4.6 1.6 1 0 0 1 1 1 0 Stage II sporulation protein Med3 PF11593.3 OAI96100.1 - 2.2 7.4 38.8 3.3 6.8 26.4 1.6 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal Ferritin_2 PF13668.1 OAI96105.1 - 1.9e-06 27.8 0.3 2.7e-06 27.3 0.2 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF3449 PF11931.3 OAI96110.1 - 4.8e-64 215.4 1.1 5.2e-64 215.3 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) zf-H2C2_5 PF13909.1 OAI96110.1 - 0.42 10.9 2.1 0.72 10.2 1.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc-finger domain PMSR PF01625.16 OAI96116.1 - 0.00011 22.1 0.1 0.011 15.6 0.0 2.2 1 1 0 1 1 1 1 Peptide methionine sulfoxide reductase Oxidored_molyb PF00174.14 OAI96117.1 - 1.9e-27 95.7 0.2 4.4e-13 48.9 0.0 2.0 1 1 1 2 2 2 2 Oxidoreductase molybdopterin binding domain DUF3089 PF11288.3 OAI96117.1 - 0.16 11.1 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) ATP-grasp_4 PF13535.1 OAI96125.1 - 2.1e-43 148.1 0.1 7.3e-38 130.1 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain ATP-grasp_3 PF02655.9 OAI96125.1 - 0.03 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain TPR_12 PF13424.1 OAI96130.1 - 4.7e-06 26.4 15.3 0.12 12.3 0.2 4.7 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_4 PF07721.9 OAI96130.1 - 0.41 11.2 7.1 41 5.0 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat adh_short_C2 PF13561.1 OAI96138.1 - 4.3e-18 65.9 0.1 4.8e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAI96138.1 - 3.7e-11 43.2 0.1 5.1e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAI96138.1 - 0.0011 18.7 0.1 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 KR domain DDOST_48kD PF03345.9 OAI96139.1 - 1e-24 86.8 0.0 1.3e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta PepSY_2 PF13670.1 OAI96139.1 - 1.8 8.4 5.3 1.7 8.5 1.1 2.4 2 1 0 2 2 2 0 Peptidase propeptide and YPEB domain OMP_b-brl_3 PF14905.1 OAI96144.1 - 0.0013 17.5 3.6 0.0016 17.1 2.5 1.0 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family TonB_dep_Rec PF00593.19 OAI96144.1 - 0.015 15.2 10.6 0.14 12.0 7.4 2.0 1 1 0 1 1 1 0 TonB dependent receptor OEP PF02321.13 OAI96144.1 - 0.025 14.1 0.3 0.038 13.5 0.2 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein STOP PF05217.7 OAI96144.1 - 0.1 12.2 0.1 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 STOP protein AAA PF00004.24 OAI96147.1 - 8.1e-16 58.4 0.1 4.3e-15 56.0 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAI96147.1 - 0.00031 20.7 0.8 0.0021 18.0 0.5 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 OAI96147.1 - 0.00079 19.1 0.4 0.002 17.8 0.3 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 OAI96147.1 - 0.0012 18.9 0.1 0.0047 17.0 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 OAI96147.1 - 0.0054 17.5 0.0 0.0083 16.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAI96147.1 - 0.007 16.0 0.1 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 OAI96147.1 - 0.0094 15.8 0.0 0.012 15.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF2442 PF10387.4 OAI96147.1 - 0.016 15.2 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) AAA_11 PF13086.1 OAI96147.1 - 0.036 13.6 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 OAI96147.1 - 0.049 13.6 0.5 0.089 12.7 0.1 1.7 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.1 OAI96147.1 - 0.05 13.0 1.1 0.37 10.1 0.8 2.0 1 1 0 1 1 1 0 AAA domain Lambda_CIII PF02061.11 OAI96151.1 - 0.033 14.1 0.1 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Lambda Phage CIII Thr_dehydrat_C PF00585.13 OAI96154.1 - 4.9e-16 58.1 0.1 1.3e-14 53.5 0.0 2.2 1 1 0 1 1 1 1 C-terminal regulatory domain of Threonine dehydratase rve PF00665.21 OAI96157.1 - 1.4e-16 60.6 0.0 3.1e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAI96157.1 - 0.025 14.1 0.0 0.081 12.4 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain zf-H2C2 PF09337.5 OAI96157.1 - 0.025 13.9 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger WD40 PF00400.27 OAI96160.1 - 3.3e-17 61.6 4.5 7.7e-07 28.7 0.0 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 OAI96160.1 - 1e-06 27.2 2.0 0.0017 16.5 0.1 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Cortex-I_coil PF09304.5 OAI96160.1 - 0.16 11.9 4.1 0.29 11.1 2.9 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil NAD_binding_5 PF07994.7 OAI96168.1 - 6.7e-23 81.6 0.0 8.8e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NPIP PF06409.6 OAI96175.1 - 0.065 11.9 1.4 0.12 11.0 1.0 1.5 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) YiiD_Cterm PF09500.5 OAI96175.1 - 0.16 11.5 1.6 0.2 11.1 0.1 1.9 2 0 0 2 2 2 0 Putative thioesterase (yiiD_Cterm) DUF4041 PF13250.1 OAI96175.1 - 0.55 9.8 3.8 20 4.8 0.1 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4041) DUF720 PF05302.6 OAI96175.1 - 0.76 9.5 11.9 0.026 14.3 2.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF720) NPV_P10 PF05531.7 OAI96175.1 - 1.2 9.3 14.0 3 8.1 0.9 4.5 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1342 PF07072.6 OAI96175.1 - 4 7.0 17.3 0.29 10.7 3.0 3.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1342) Filament PF00038.16 OAI96175.1 - 9.9 5.5 37.9 2.7 7.3 4.9 3.8 1 1 3 4 4 4 0 Intermediate filament protein Pro_Al_protease PF02983.9 OAI96178.1 - 0.12 12.3 0.2 0.23 11.4 0.0 1.5 2 0 0 2 2 2 0 Alpha-lytic protease prodomain COX1 PF00115.15 OAI96179.1 - 2.4e-160 534.0 58.1 2.7e-160 533.8 40.3 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I HAMP PF00672.20 OAI96181.1 - 3.2e-11 43.2 1.4 1e-10 41.6 1.0 1.9 1 0 0 1 1 1 1 HAMP domain TarH PF02203.10 OAI96181.1 - 2.3e-06 27.5 3.1 4.4e-06 26.6 2.1 1.5 1 0 0 1 1 1 1 Tar ligand binding domain homologue 4HB_MCP_1 PF12729.2 OAI96181.1 - 0.046 13.0 0.2 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Asn_synthase PF00733.16 OAI96185.1 - 2.3e-08 33.8 0.0 3.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase zf-C2H2 PF00096.21 OAI96188.1 - 8.1e-06 25.8 0.1 1.8e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAI96188.1 - 0.0084 16.3 0.6 0.02 15.1 0.1 1.8 2 0 0 2 2 2 1 C2H2-type zinc finger Retrotrans_gag PF03732.12 OAI96193.1 - 0.0052 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Sec8_exocyst PF04048.9 OAI96193.1 - 0.079 12.5 0.0 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Golgin_A5 PF09787.4 OAI96193.1 - 2.1 6.7 8.1 2.9 6.3 5.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF605 PF04652.11 OAI96201.1 - 3.6 6.8 7.7 3.6 6.8 5.3 1.0 1 0 0 1 1 1 0 Vta1 like Helicase_C_4 PF13871.1 OAI96205.1 - 8.7e-44 150.0 0.0 1.3e-43 149.4 0.0 1.2 1 0 0 1 1 1 1 Helicase_C-like CFEM PF05730.6 OAI96208.1 - 8.6e-09 35.1 11.5 1.6e-08 34.2 8.0 1.4 1 0 0 1 1 1 1 CFEM domain PEP-utilizers PF00391.18 OAI96208.1 - 0.27 10.8 3.8 0.69 9.5 0.0 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain Hydrolase_like PF13242.1 OAI96209.1 - 1.8e-13 49.9 0.0 1.9e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 HAD-hyrolase-like PGP_phosphatase PF09419.5 OAI96209.1 - 0.021 14.1 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Hydrolase PF00702.21 OAI96209.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Catalase PF00199.14 OAI96217.1 - 1.1e-57 195.4 0.0 1.4e-57 195.1 0.0 1.0 1 0 0 1 1 1 1 Catalase DUF3435 PF11917.3 OAI96222.1 - 0.021 13.5 0.1 0.03 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) RRM_1 PF00076.17 OAI96228.1 - 2.8e-06 26.8 0.0 3.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAI96228.1 - 1.1e-05 25.2 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAI96228.1 - 1.7e-05 24.6 0.0 2.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DDE_Tnp_4 PF13359.1 OAI96232.1 - 1.5e-14 53.9 0.0 2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Abhydro_lipase PF04083.11 OAI96235.1 - 0.061 12.6 0.1 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Pyr_redox_3 PF13738.1 OAI96237.1 - 1.5e-22 80.6 0.0 2.1e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAI96237.1 - 7.7e-14 50.7 0.0 1e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAI96237.1 - 1.1e-12 47.5 0.0 1.2e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAI96237.1 - 1.1e-10 41.4 0.0 5.7e-08 32.6 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAI96237.1 - 3.2e-08 33.4 0.0 1.2e-05 25.0 0.0 3.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAI96237.1 - 3.2e-07 30.4 0.0 2.1e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAI96237.1 - 8.2e-07 28.2 0.1 0.013 14.3 0.0 3.1 2 1 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 OAI96237.1 - 4.3e-05 22.1 0.0 0.21 9.9 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.22 OAI96237.1 - 0.00017 21.8 0.0 0.073 13.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAI96237.1 - 0.0042 16.2 0.0 0.056 12.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 OAI96237.1 - 0.051 13.8 0.0 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 OAI96237.1 - 0.055 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DSHCT PF08148.7 OAI96242.1 - 7.5e-28 96.9 0.2 1.7e-27 95.8 0.1 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain Pkinase PF00069.20 OAI96246.1 - 1.2e-26 93.3 0.0 1.7e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI96246.1 - 3e-10 39.6 0.0 4e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI96246.1 - 0.037 12.9 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like FliD_N PF02465.13 OAI96248.1 - 0.00026 21.2 0.9 0.0016 18.7 0.3 2.0 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 N-terminus DUF1814 PF08843.6 OAI96257.1 - 0.0009 19.0 0.5 0.038 13.7 0.3 2.1 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) RVT_3 PF13456.1 OAI96259.1 - 0.038 13.7 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like DNA_pol_viral_C PF00336.13 OAI96259.1 - 0.059 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Peptidase_MA_2 PF13485.1 OAI96274.1 - 0.031 14.3 0.7 0.079 13.0 0.1 2.1 2 1 0 2 2 2 0 Peptidase MA superfamily Velvet PF11754.3 OAI96283.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Velvet factor DDE_1 PF03184.14 OAI96286.1 - 1.3e-43 148.7 0.0 2.1e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAI96286.1 - 8.7e-15 54.2 0.2 2.7e-14 52.6 0.1 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 OAI96286.1 - 1.2e-05 25.0 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Allantoicase PF03561.10 OAI96286.1 - 0.053 12.9 0.0 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 Allantoicase repeat HTH_26 PF13443.1 OAI96286.1 - 0.12 12.5 0.0 0.48 10.6 0.2 1.9 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Methyltransf_6 PF03737.10 OAI96289.1 - 3.4e-26 91.9 0.0 4.6e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 Demethylmenaquinone methyltransferase AMP-binding PF00501.23 OAI96290.1 - 2e-06 26.5 0.0 2.4e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Dimer_Tnp_hAT PF05699.9 OAI96301.1 - 1.8e-08 33.9 0.0 2.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CMV_1a PF12467.3 OAI96301.1 - 0.00065 20.1 0.3 0.00076 19.9 0.2 1.1 1 0 0 1 1 1 1 Cucumber mosaic virus 1a protein family DUF922 PF06037.6 OAI96304.1 - 0.58 9.4 6.7 0.11 11.8 2.1 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) RVT_1 PF00078.22 OAI96307.1 - 1.5e-17 63.6 0.0 2.6e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAI96307.1 - 0.0018 18.7 0.5 0.0053 17.2 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI96307.1 - 0.025 14.3 1.7 0.14 11.9 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAI96307.1 - 0.028 14.3 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-met PF12874.2 OAI96308.1 - 3.5e-06 27.0 1.6 4.4e-06 26.6 0.6 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PAS PF00989.19 OAI96310.1 - 5.3e-21 74.5 0.2 8.4e-10 38.4 0.0 3.2 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.1 OAI96310.1 - 1.3e-13 50.2 0.1 2.8e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.6 OAI96310.1 - 7.8e-12 45.1 0.3 8.7e-08 32.1 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.1 OAI96310.1 - 8.5e-09 35.7 0.0 0.018 15.3 0.0 3.2 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.5 OAI96310.1 - 2.7e-08 33.8 3.1 0.0012 18.8 0.1 3.2 3 0 0 3 3 3 2 PAS fold DUF1418 PF07214.7 OAI96310.1 - 0.02 14.5 0.3 0.041 13.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) DUF1469 PF07332.6 OAI96310.1 - 0.17 11.6 3.0 0.33 10.6 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DNA_methylase PF00145.12 OAI96312.1 - 1.5e-26 93.3 0.0 2.2e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase RE_EcoO109I PF14511.1 OAI96313.1 - 1.3e-17 63.9 0.0 1.7e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Type II restriction endonuclease EcoO109I SoxE PF06525.6 OAI96324.1 - 3.9 6.7 5.9 0.51 9.5 0.2 2.0 2 0 0 2 2 2 0 Sulfocyanin (SoxE) CRAL_TRIO_N PF03765.10 OAI96328.1 - 7.9e-14 51.5 0.5 1.7e-13 50.4 0.3 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CdCA1 PF10563.4 OAI96328.1 - 0.079 12.4 0.3 0.31 10.5 0.1 1.8 2 0 0 2 2 2 0 Cadmium carbonic anhydrase repeat p450 PF00067.17 OAI96332.1 - 2.3e-10 39.6 0.0 2.7e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 End3 PF12761.2 OAI96332.1 - 0.099 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 TPR_19 PF14559.1 OAI96339.1 - 4e-10 39.8 24.2 0.0011 19.2 0.2 5.9 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 OAI96339.1 - 1.9e-05 24.8 42.6 0.0069 16.9 0.0 8.4 3 2 6 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 OAI96339.1 - 0.00028 21.4 32.5 0.076 13.7 0.7 5.5 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_20 PF14561.1 OAI96339.1 - 0.0016 18.5 9.6 0.15 12.2 0.1 3.8 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAI96339.1 - 0.035 14.0 6.5 15 5.8 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAI96339.1 - 0.091 13.2 10.7 24 5.6 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAI96339.1 - 0.35 10.7 7.3 2.5 8.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3425 PF11905.3 OAI96339.1 - 1 9.2 5.7 37 4.2 4.0 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3425) DUF4328 PF14219.1 OAI96345.1 - 0.0084 15.4 0.2 0.036 13.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4328) RVT_2 PF07727.9 OAI96357.1 - 4.3e-42 143.7 0.0 5.4e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 OAI96357.1 - 0.066 12.9 0.0 0.19 11.5 0.0 1.9 1 0 0 1 1 1 0 Reverse transcriptase-like Myb_DNA-bind_3 PF12776.2 OAI96358.1 - 0.0011 19.5 0.4 0.0022 18.5 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain PBP1_TM PF14812.1 OAI96358.1 - 0.012 15.9 2.5 0.023 15.0 1.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0167 PF03691.9 OAI96358.1 - 0.068 12.5 0.5 0.12 11.8 0.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0167) Sigma70_ner PF04546.8 OAI96358.1 - 0.14 11.7 1.9 0.15 11.6 1.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.5 OAI96358.1 - 0.27 10.2 5.8 0.32 10.0 4.0 1.0 1 0 0 1 1 1 0 BUD22 Nucleoplasmin PF03066.10 OAI96358.1 - 0.72 9.3 4.1 0.85 9.1 2.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin Phage_integrase PF00589.17 OAI96364.1 - 3.2e-05 23.6 0.0 3.8e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family DUF433 PF04255.9 OAI96364.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF433) DcpS_C PF11969.3 OAI96367.1 - 0.024 14.8 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Thi4 PF01946.12 OAI96370.1 - 0.067 12.2 1.2 3.7 6.5 0.0 2.1 1 1 1 2 2 2 0 Thi4 family rve PF00665.21 OAI96374.1 - 7.4e-15 55.1 0.0 1.3e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.12 OAI96378.1 - 0.041 13.9 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein DUF3549 PF12069.3 OAI96380.1 - 0.034 12.9 0.3 0.049 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) HK97-gp10_like PF04883.7 OAI96380.1 - 0.053 14.4 0.2 1.2 10.0 0.2 2.2 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Acyl-CoA_ox_N PF14749.1 OAI96388.1 - 5.4e-16 59.0 0.0 8.4e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 OAI96388.1 - 2.1e-05 23.9 0.0 4.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF4611 PF15387.1 OAI96391.1 - 0.011 15.8 3.2 0.25 11.5 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.5 OAI96391.1 - 0.014 15.6 5.3 0.021 15.0 3.7 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.7 OAI96391.1 - 0.016 13.1 0.5 0.017 13.1 0.4 1.2 1 0 0 1 1 1 0 Nop14-like family Packaging_FI PF14000.1 OAI96391.1 - 0.097 12.8 1.7 0.14 12.3 0.2 1.8 2 0 0 2 2 2 0 DNA packaging protein FI DUF2890 PF11081.3 OAI96391.1 - 0.13 12.2 1.9 0.19 11.7 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) ANAPC15 PF15243.1 OAI96391.1 - 0.14 12.2 6.1 0.28 11.2 4.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 CobT PF06213.7 OAI96391.1 - 0.17 10.9 3.6 0.27 10.3 2.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.8 OAI96391.1 - 0.17 9.6 8.4 0.24 9.1 5.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nucleoplasmin PF03066.10 OAI96391.1 - 0.28 10.6 7.8 0.44 10.0 5.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 OAI96391.1 - 1.8 6.3 7.1 3 5.6 4.9 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.8 OAI96391.1 - 8.9 5.8 11.4 12 5.4 7.9 1.6 1 1 0 1 1 1 0 Sigma-70, non-essential region VAD1-2 PF15310.1 OAI96392.1 - 3.6 7.1 5.6 4.2 6.9 3.9 1.1 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling Spore_coat_CotO PF14153.1 OAI96392.1 - 5.2 6.4 9.8 5.8 6.3 6.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Vfa1 PF08432.5 OAI96392.1 - 6.3 6.7 12.9 7.1 6.6 8.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2722 PF10846.3 OAI96392.1 - 7.2 5.5 10.2 7.3 5.4 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RNA_pol_Rpc4 PF05132.9 OAI96392.1 - 8.3 6.4 7.0 10 6.0 4.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Apolipoprotein PF01442.13 OAI96398.1 - 0.00079 18.9 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 OAI96398.1 - 0.043 14.2 0.3 0.043 14.2 0.2 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Asp PF00026.18 OAI96402.1 - 2.7e-15 56.4 0.0 3.2e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Phage_integrase PF00589.17 OAI96404.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Phage integrase family DUF1253 PF06862.7 OAI96409.1 - 1.9e-32 112.2 0.0 2.2e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DUF1253 PF06862.7 OAI96410.1 - 8.3e-06 24.4 0.0 1.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) CDV3 PF15359.1 OAI96412.1 - 2.3 8.2 15.2 1.6 8.7 9.3 1.5 1 1 0 1 1 1 0 Carnitine deficiency-associated protein 3 DUF605 PF04652.11 OAI96412.1 - 2.8 7.2 15.0 3.4 6.9 10.4 1.2 1 0 0 1 1 1 0 Vta1 like Phage_int_SAM_1 PF02899.12 OAI96414.1 - 0.01 16.0 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain PIN PF01850.16 OAI96417.1 - 0.14 12.4 1.1 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 PIN domain FlaC_arch PF05377.6 OAI96417.1 - 0.24 11.3 1.2 0.55 10.1 0.8 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Resolvase PF00239.16 OAI96420.1 - 4.6e-31 107.5 0.0 5e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Resolvase, N terminal domain GRP PF07172.6 OAI96429.1 - 0.081 13.4 9.8 0.16 12.4 6.8 1.4 1 0 0 1 1 1 0 Glycine rich protein family zf-CCHC PF00098.18 OAI96429.1 - 0.62 10.0 11.2 0.47 10.4 6.1 2.1 2 0 0 2 2 2 0 Zinc knuckle RVT_3 PF13456.1 OAI96430.1 - 0.0092 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like PP2C PF00481.16 OAI96437.1 - 8.1e-12 45.0 0.0 1.2e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C zf-CCHC PF00098.18 OAI96441.1 - 6.2e-07 29.0 0.7 9.6e-07 28.4 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAI96441.1 - 0.0012 18.3 0.5 0.0026 17.2 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Yae1_N PF09811.4 OAI96441.1 - 0.037 13.5 2.1 0.08 12.4 1.4 1.5 1 0 0 1 1 1 0 Essential protein Yae1, N terminal SNARE_assoc PF09335.6 OAI96443.1 - 1.1e-21 77.2 5.7 1.1e-21 77.2 4.0 2.8 3 0 0 3 3 3 1 SNARE associated Golgi protein Pyr_redox_2 PF07992.9 OAI96443.1 - 1.6e-07 31.3 0.0 2.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAI96443.1 - 1.4e-05 24.3 0.2 1.9e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 OAI96443.1 - 3.2e-05 23.0 0.1 4.4e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAI96443.1 - 0.0015 18.5 0.1 0.0028 17.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 OAI96443.1 - 0.0016 17.5 0.0 0.003 16.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 OAI96443.1 - 0.007 15.2 1.7 0.011 14.5 1.0 1.4 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 OAI96443.1 - 0.0099 14.3 0.8 0.013 13.9 0.6 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 OAI96443.1 - 0.019 13.6 0.1 0.024 13.2 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 OAI96443.1 - 0.053 13.9 0.9 0.13 12.7 0.6 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAI96443.1 - 0.11 11.3 0.7 0.14 10.9 0.5 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Vma12 PF11712.3 OAI96443.1 - 2.4 7.8 6.9 4.1 7.1 1.6 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PHD PF00628.24 OAI96446.1 - 0.54 9.9 11.0 0.19 11.4 4.1 2.5 2 1 1 3 3 3 0 PHD-finger zf-RING-like PF08746.6 OAI96446.1 - 3.5 7.6 6.5 0.84 9.6 0.7 2.3 2 0 0 2 2 2 0 RING-like domain rve PF00665.21 OAI96453.1 - 2.9e-20 72.5 0.1 6.7e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAI96453.1 - 0.0017 17.8 0.0 0.004 16.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain MULE PF10551.4 OAI96456.1 - 1.9e-10 40.7 0.0 4.6e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAI96456.1 - 0.0004 19.0 0.0 0.00067 18.3 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Phage_integrase PF00589.17 OAI96459.1 - 5.3e-06 26.2 1.1 1.7e-05 24.5 0.0 2.3 3 0 0 3 3 3 1 Phage integrase family Phage_int_SAM_4 PF13495.1 OAI96459.1 - 0.096 13.0 0.0 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain RIC3 PF15361.1 OAI96461.1 - 0.11 12.7 1.2 0.15 12.2 0.8 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 PHP PF02811.14 OAI96463.1 - 8.6e-10 38.6 0.3 1.8e-09 37.6 0.2 1.6 1 1 0 1 1 1 1 PHP domain RNA_pol_Rpb4 PF03874.11 OAI96468.1 - 1e-14 54.5 0.0 5.1e-14 52.2 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb4 PsaX PF08078.7 OAI96469.1 - 8.6 6.3 6.5 32 4.5 3.3 2.5 2 1 0 2 2 2 0 PsaX family Ail_Lom PF06316.6 OAI96474.1 - 0.34 10.3 0.1 0.34 10.3 0.0 1.8 3 0 0 3 3 3 0 Enterobacterial Ail/Lom protein GRP PF07172.6 OAI96474.1 - 7.2 7.1 24.9 0.44 11.0 0.1 3.2 2 1 0 3 3 3 0 Glycine rich protein family Rad60-SLD PF11976.3 OAI96477.1 - 0.0026 17.3 0.1 0.01 15.4 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like RNase_H PF00075.19 OAI96484.1 - 7.4e-16 58.6 0.1 1.3e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 RNase H Asp PF00026.18 OAI96486.1 - 9.4e-17 61.2 8.7 1e-16 61.0 4.7 2.0 2 1 0 2 2 2 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 OAI96486.1 - 0.00036 20.9 1.7 0.0011 19.4 0.3 2.3 2 1 1 3 3 3 1 Aspartyl protease TAXi_N PF14543.1 OAI96486.1 - 0.0005 20.0 0.8 0.0027 17.6 0.5 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal BBP1_C PF15272.1 OAI96489.1 - 3.3 7.2 12.9 5.7 6.4 8.9 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Vfa1 PF08432.5 OAI96489.1 - 7.2 6.5 13.3 12 5.9 9.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF336 PF03928.9 OAI96491.1 - 2e-21 76.1 0.2 2.2e-21 76.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF336) GAF_2 PF13185.1 OAI96491.1 - 0.054 13.9 0.0 0.055 13.9 0.0 1.2 1 0 0 1 1 1 0 GAF domain Transthyretin PF00576.16 OAI96492.1 - 7.1e-36 122.5 0.0 8.2e-36 122.2 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family MG1 PF11974.3 OAI96492.1 - 0.00055 20.4 0.0 0.00071 20.0 0.0 1.1 1 0 0 1 1 1 1 Alpha-2-macroglobulin MG1 domain DUF4469 PF14734.1 OAI96492.1 - 0.014 15.2 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold A2M_N PF01835.14 OAI96492.1 - 0.016 15.4 0.1 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 MG2 domain Big_1 PF02369.11 OAI96492.1 - 0.021 14.7 0.1 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) DUF824 PF05688.6 OAI96492.1 - 0.041 13.5 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) CarboxypepD_reg PF13620.1 OAI96492.1 - 0.073 13.1 0.1 0.17 11.9 0.1 1.6 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain CopC PF04234.7 OAI96492.1 - 0.14 12.7 0.0 0.19 12.3 0.0 1.2 1 0 0 1 1 1 0 CopC domain Cna_B PF05738.8 OAI96492.1 - 0.16 11.7 1.0 0.31 10.8 0.7 1.5 1 1 0 1 1 1 0 Cna protein B-type domain DUF4280 PF14107.1 OAI96493.1 - 6.8e-25 87.4 0.0 7.5e-25 87.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4280) Retrotrans_gag PF03732.12 OAI96495.1 - 0.082 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein DUF2205 PF10224.4 OAI96495.1 - 0.082 12.4 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Sec8_exocyst PF04048.9 OAI96495.1 - 0.2 11.2 0.0 0.54 9.8 0.0 1.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain zf-C4H2 PF10146.4 OAI96495.1 - 0.22 11.5 0.9 0.55 10.2 0.6 1.7 1 0 0 1 1 1 0 Zinc finger-containing protein Golgin_A5 PF09787.4 OAI96495.1 - 2.6 6.4 6.9 3.7 5.9 4.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Phage_Nu1 PF07471.7 OAI96497.1 - 0.017 14.6 2.2 0.026 13.9 1.5 1.2 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 HTH_6 PF01418.12 OAI96497.1 - 0.052 13.2 0.1 10 5.9 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family Hydant_A_N PF05378.8 OAI96499.1 - 2.1e-57 193.4 0.8 3.4e-55 186.2 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.13 OAI96499.1 - 5.3e-25 88.1 1.6 5.5e-23 81.4 0.6 2.2 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Muskelin_N PF06588.6 OAI96503.1 - 5.6e-17 62.0 0.0 7.7e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Muskelin N-terminus An_peroxidase PF03098.10 OAI96505.1 - 9.6e-40 136.4 0.0 1.3e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase BRO1 PF03097.13 OAI96507.1 - 3.9e-05 22.5 0.0 5.1e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain Luteo_Vpg PF01659.11 OAI96507.1 - 0.73 9.5 12.9 0.14 11.9 1.1 2.2 1 1 1 2 2 2 0 Luteovirus putative VPg genome linked protein Phage_int_SAM_1 PF02899.12 OAI96517.1 - 0.045 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF659 PF04937.10 OAI96519.1 - 0.055 12.9 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) ParBc PF02195.13 OAI96522.1 - 7.7e-14 51.5 0.0 1.3e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 ParB-like nuclease domain HTH_31 PF13560.1 OAI96522.1 - 0.0011 19.0 1.4 0.0041 17.2 0.2 2.5 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 OAI96522.1 - 0.0012 18.8 0.0 0.013 15.5 0.0 2.4 1 1 1 2 2 2 1 Helix-turn-helix domain KorB PF08535.5 OAI96522.1 - 0.032 14.3 0.0 0.077 13.1 0.0 1.7 1 0 0 1 1 1 0 KorB domain HTH_37 PF13744.1 OAI96522.1 - 0.086 12.6 0.0 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 OAI96522.1 - 0.1 12.3 0.3 1.4 8.6 0.0 2.8 2 1 0 2 2 2 0 Homeodomain-like domain CbiA PF01656.18 OAI96523.1 - 6.3e-13 48.5 0.1 8.3e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 OAI96523.1 - 0.00086 18.4 0.1 0.0012 17.9 0.1 1.2 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 OAI96523.1 - 0.009 15.9 0.1 0.04 13.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AA_permease_2 PF13520.1 OAI96540.1 - 2.6e-39 134.9 24.2 9.6e-39 133.1 16.8 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAI96540.1 - 4.2e-12 45.1 17.3 4.2e-12 45.1 12.0 1.9 2 0 0 2 2 2 1 Amino acid permease Fungal_trans PF04082.13 OAI96542.1 - 2.4e-09 36.4 0.0 4e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SGL PF08450.7 OAI96550.1 - 1.4e-34 119.5 0.1 1.7e-34 119.3 0.1 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 OAI96550.1 - 1.5e-07 31.0 1.3 0.11 12.5 0.0 3.6 3 0 0 3 3 3 2 NHL repeat Reg_prop PF07494.6 OAI96550.1 - 3.4e-05 23.3 1.5 0.24 11.5 0.1 3.1 2 1 0 2 2 2 2 Two component regulator propeller Str_synth PF03088.11 OAI96550.1 - 0.04 13.9 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Strictosidine synthase RR_TM4-6 PF06459.7 OAI96553.1 - 2 8.2 15.8 2.5 7.9 11.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF572 PF04502.8 OAI96553.1 - 4.4 6.4 23.0 5.1 6.2 15.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MIP-T3 PF10243.4 OAI96553.1 - 6.7 5.0 32.8 7.1 4.9 22.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Sulfatase PF00884.18 OAI96555.1 - 5.7e-34 117.6 0.0 6.3e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 OAI96555.1 - 0.086 12.1 0.0 0.099 11.9 0.0 1.1 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DNA_gyraseA_C PF03989.8 OAI96560.1 - 0.038 13.3 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller PAP2 PF01569.16 OAI96561.1 - 6.2e-17 61.4 2.2 1.2e-16 60.5 1.6 1.4 1 0 0 1 1 1 1 PAP2 superfamily SpoVAB PF13782.1 OAI96561.1 - 0.13 12.2 0.7 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Stage V sporulation protein AB YhhN PF07947.9 OAI96561.1 - 0.91 8.8 7.8 0.42 9.9 1.2 2.2 2 0 0 2 2 2 0 YhhN-like protein FdhE PF04216.7 OAI96562.1 - 0.15 11.7 0.5 0.18 11.5 0.4 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation YopE PF03545.8 OAI96562.1 - 1.2 9.1 4.6 3.7 7.5 0.5 2.3 1 1 1 2 2 2 0 Yersinia virulence determinant (YopE) TPR_5 PF12688.2 OAI96566.1 - 0.023 14.7 0.0 0.026 14.5 0.0 1.1 1 0 0 1 1 1 0 Tetratrico peptide repeat Histone PF00125.19 OAI96566.1 - 0.05 13.7 0.1 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 YscJ_FliF_C PF08345.6 OAI96566.1 - 0.059 13.3 0.0 0.061 13.2 0.0 1.1 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal TMEM171 PF15471.1 OAI96569.1 - 0.39 9.4 2.1 0.7 8.6 1.4 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 DDE_Tnp_4 PF13359.1 OAI96570.1 - 1.5e-22 79.8 0.0 1.8e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 OAI96570.1 - 0.00016 21.2 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain Pyr_redox_2 PF07992.9 OAI96572.1 - 1.7e-11 44.3 2.3 4.2e-10 39.8 1.6 3.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAI96572.1 - 4.2e-09 36.7 3.5 5.4e-05 23.3 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAI96572.1 - 7.3e-09 35.9 4.7 2e-08 34.5 0.0 2.9 4 0 0 4 4 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAI96572.1 - 9.7e-07 28.0 1.2 2.9e-05 23.1 0.1 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 OAI96572.1 - 1.2e-05 25.5 3.8 0.0049 17.1 0.1 3.4 3 1 0 3 3 3 1 Putative NAD(P)-binding TrkA_N PF02254.13 OAI96572.1 - 9.5e-05 22.3 1.3 0.31 11.0 0.0 3.1 3 0 0 3 3 3 2 TrkA-N domain ThiF PF00899.16 OAI96572.1 - 0.00072 19.3 1.5 0.31 10.8 0.0 3.6 4 0 0 4 4 4 1 ThiF family Trp_halogenase PF04820.9 OAI96572.1 - 0.00098 17.8 2.9 0.0052 15.4 0.1 2.4 2 1 1 3 3 3 1 Tryptophan halogenase DAO PF01266.19 OAI96572.1 - 0.0032 16.4 6.6 0.031 13.1 0.1 3.6 3 1 1 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAI96572.1 - 0.0034 17.1 2.2 2.5 7.8 0.0 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 OAI96572.1 - 0.0037 16.2 1.2 0.97 8.2 0.1 2.4 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAI96572.1 - 0.0057 16.6 0.1 0.029 14.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Abhydrolase_6 PF12697.2 OAI96572.1 - 0.0071 16.2 0.1 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Shikimate_DH PF01488.15 OAI96572.1 - 0.0078 16.3 2.7 0.69 10.0 0.0 3.1 4 0 0 4 4 4 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 OAI96572.1 - 0.023 13.7 0.2 2.6 7.0 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain HI0933_like PF03486.9 OAI96572.1 - 0.088 11.2 3.0 3 6.2 0.0 3.5 2 1 2 4 4 4 0 HI0933-like protein Abhydrolase_5 PF12695.2 OAI96572.1 - 0.093 12.4 3.3 0.45 10.2 0.1 2.4 1 1 1 2 2 2 0 Alpha/beta hydrolase family Ldh_1_N PF00056.18 OAI96572.1 - 0.27 11.0 2.5 11 5.8 0.0 3.1 2 1 1 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 OAI96572.1 - 0.34 11.4 2.0 12 6.4 0.0 3.4 3 1 1 4 4 4 0 Oxidoreductase family, NAD-binding Rossmann fold PEMT PF04191.8 OAI96584.1 - 2.8e-34 117.4 5.8 2.8e-34 117.4 4.0 1.4 2 0 0 2 2 2 1 Phospholipid methyltransferase EI24 PF07264.6 OAI96584.1 - 0.006 16.0 6.8 0.01 15.3 4.2 1.6 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) ICMT PF04140.9 OAI96584.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family FG-GAP PF01839.18 OAI96586.1 - 0.014 15.1 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 FG-GAP repeat Corona_nucleoca PF00937.13 OAI96586.1 - 0.71 8.7 9.4 0.99 8.2 6.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF2730 PF10805.3 OAI96595.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Retrotrans_gag PF03732.12 OAI96595.1 - 0.043 13.8 0.1 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2360 PF10152.4 OAI96595.1 - 1.4 9.1 7.1 5.8 7.1 1.1 2.8 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Abhydrolase_5 PF12695.2 OAI96604.1 - 4e-07 29.8 0.2 8.1e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAI96604.1 - 0.00019 21.3 0.4 0.00032 20.6 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAI96604.1 - 0.043 13.3 0.1 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1749 PF08538.5 OAI96604.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) TFIIA PF03153.8 OAI96609.1 - 1.1 9.0 12.4 1.3 8.8 8.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit rve PF00665.21 OAI96612.1 - 6.2e-22 77.9 0.1 1.1e-21 77.1 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAI96612.1 - 0.00067 19.1 0.0 0.0018 17.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 OAI96612.1 - 0.083 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 DDE domain RVT_3 PF13456.1 OAI96623.1 - 0.005 16.5 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like DNA_pol_viral_C PF00336.13 OAI96623.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain RVT_1 PF00078.22 OAI96628.1 - 1.9e-23 82.9 0.0 2.6e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 OAI96638.1 - 1e-26 93.6 0.0 1.2e-23 83.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAI96638.1 - 4.5e-13 48.8 0.0 7.3e-10 38.3 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase CRS1_YhbY PF01985.16 OAI96646.1 - 0.09 12.7 0.6 0.21 11.6 0.1 1.7 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain DUF4218 PF13960.1 OAI96652.1 - 0.031 13.7 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Leu_zip PF15294.1 OAI96652.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Leucine zipper Pkinase PF00069.20 OAI96655.1 - 4e-08 32.7 0.0 4.5e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Mononeg_mRNAcap PF14318.1 OAI96655.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V ELFV_dehydrog_N PF02812.13 OAI96657.1 - 2.2e-15 56.3 0.0 3.8e-15 55.6 0.0 1.4 1 1 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF2215 PF10225.4 OAI96659.1 - 0.025 14.0 0.1 0.042 13.3 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF3306 PF11748.3 OAI96659.1 - 0.66 10.6 8.0 0.84 10.3 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) FAD_binding_8 PF08022.7 OAI96662.1 - 3.2e-19 68.7 0.0 1.1e-18 67.0 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 OAI96662.1 - 1.2e-14 54.4 0.0 1.5e-13 50.9 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 OAI96662.1 - 3.3e-09 36.8 4.7 7.7e-09 35.7 3.3 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 OAI96662.1 - 0.00056 19.9 0.0 0.0024 17.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain DUF2119 PF09892.4 OAI96662.1 - 0.2 10.9 0.0 4.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2119) rve PF00665.21 OAI96666.1 - 2.6e-20 72.6 0.0 4.1e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 OAI96666.1 - 0.0019 18.1 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 DDE domain DUF2305 PF10230.4 OAI96670.1 - 1.1e-46 159.4 0.0 7.3e-46 156.7 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 OAI96670.1 - 1.3e-08 35.0 1.5 2.3e-08 34.2 1.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAI96670.1 - 6e-06 26.0 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAI96670.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 OAI96670.1 - 0.038 13.5 0.1 0.18 11.3 0.1 2.1 3 0 0 3 3 3 0 Serine hydrolase PGAP1 PF07819.8 OAI96670.1 - 0.045 13.3 0.1 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 OAI96670.1 - 0.14 11.7 0.1 0.33 10.5 0.1 1.7 1 1 0 1 1 1 0 Lipase (class 3) DUF3089 PF11288.3 OAI96670.1 - 0.19 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) TMEM191C PF15194.1 OAI96670.1 - 0.19 11.5 2.3 0.42 10.5 1.6 1.6 1 0 0 1 1 1 0 TMEM191C family DDE_Tnp_Tn3 PF01526.12 OAI96676.1 - 2e-97 326.2 0.0 1.6e-69 234.4 0.0 2.2 1 1 1 2 2 2 2 Tn3 transposase DDE domain Acetyltransf_7 PF13508.1 OAI96680.1 - 0.00024 21.2 0.0 0.00065 19.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain SH3_2 PF07653.12 OAI96681.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 1 0 1 1 1 0 Variant SH3 domain GATase_2 PF00310.16 OAI96686.1 - 2.1e-10 39.8 0.1 2.1e-10 39.8 0.1 1.0 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DUF3288 PF11691.3 OAI96688.1 - 0.076 12.7 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3288) Nucleoplasmin PF03066.10 OAI96694.1 - 0.003 17.0 1.6 0.0033 16.9 1.1 1.2 1 0 0 1 1 1 1 Nucleoplasmin Myc_N PF01056.13 OAI96694.1 - 0.016 14.4 6.9 0.024 13.8 4.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_60s PF00428.14 OAI96694.1 - 0.047 14.0 12.7 0.085 13.2 8.8 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein BSP_II PF05432.6 OAI96694.1 - 0.053 12.8 13.5 0.062 12.5 9.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TRAP_alpha PF03896.11 OAI96694.1 - 0.084 11.8 1.6 0.11 11.5 1.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.5 OAI96694.1 - 0.21 11.8 6.5 0.38 11.0 4.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Daxx PF03344.10 OAI96694.1 - 0.42 9.0 5.1 0.5 8.8 3.5 1.1 1 0 0 1 1 1 0 Daxx Family Med4 PF10018.4 OAI96694.1 - 1.2 8.5 6.6 34 3.7 0.0 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 UDPG_MGDP_dh PF00984.14 OAI96695.1 - 9.1e-19 67.4 0.0 1.1e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain PRRSV_Env PF02340.10 OAI96695.1 - 0.01 15.0 0.1 0.012 14.8 0.0 1.1 1 0 0 1 1 1 0 PRRSV putative envelope protein DUF2824 PF11039.3 OAI96695.1 - 0.098 12.3 0.0 0.098 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) WD40 PF00400.27 OAI96700.1 - 9.7e-56 183.7 6.9 2.9e-12 45.9 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 OAI96700.1 - 0.0012 17.1 1.6 0.51 8.4 0.3 3.2 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Phlebovirus_G2 PF07245.6 OAI96700.1 - 0.11 10.6 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Nif11 PF07862.6 OAI96701.1 - 0.041 13.8 0.2 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function TilS PF09179.6 OAI96701.1 - 0.05 13.6 0.2 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 TilS substrate binding domain PilO PF04350.8 OAI96701.1 - 0.058 13.2 1.5 0.069 13.0 1.1 1.1 1 0 0 1 1 1 0 Pilus assembly protein, PilO DUF1484 PF07363.6 OAI96701.1 - 0.087 13.1 1.8 0.34 11.2 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1484) MMPL PF03176.10 OAI96701.1 - 0.089 11.4 0.2 0.094 11.4 0.1 1.0 1 0 0 1 1 1 0 MMPL family RVT_1 PF00078.22 OAI96706.1 - 1e-17 64.2 0.0 1.5e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LysR_substrate PF03466.15 OAI96709.1 - 2.7e-22 78.8 1.3 4.1e-22 78.3 0.3 1.7 1 1 1 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.22 OAI96709.1 - 8.7e-20 70.2 2.0 2.5e-19 68.7 0.6 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Oxidored_nitro PF00148.14 OAI96709.1 - 0.03 12.9 0.0 0.051 12.2 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase HTH_18 PF12833.2 OAI96710.1 - 8.6e-19 67.4 1.1 2e-18 66.2 0.8 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.18 OAI96710.1 - 2e-07 30.5 0.0 0.00021 21.0 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family SBP_bac_5 PF00496.17 OAI96710.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Aldedh PF00171.17 OAI96714.1 - 1.6e-10 39.9 0.0 1.6e-10 39.9 0.0 1.6 2 0 0 2 2 2 1 Aldehyde dehydrogenase family HsbA PF12296.3 OAI96717.1 - 6e-08 32.5 7.9 7.5e-08 32.2 5.4 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A FUN14 PF04930.10 OAI96717.1 - 0.087 13.1 1.1 0.12 12.6 0.8 1.4 1 1 0 1 1 1 0 FUN14 family Inhibitor_I53 PF11714.3 OAI96720.1 - 0.0053 16.7 0.4 0.015 15.3 0.3 1.7 1 0 0 1 1 1 1 Thrombin inhibitor Madanin Dsl1_C PF11989.3 OAI96720.1 - 0.0082 15.3 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal SDA1 PF05285.7 OAI96720.1 - 8.7 5.5 13.8 0.17 11.1 4.4 1.7 2 0 0 2 2 2 0 SDA1 RVT_2 PF07727.9 OAI96722.1 - 3.5e-77 258.6 0.0 4.5e-77 258.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PTPA PF03095.10 OAI96726.1 - 1.4e-87 293.7 0.0 1.7e-87 293.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein YqaJ PF09588.5 OAI96726.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain TonB_dep_Rec PF00593.19 OAI96729.1 - 2e-25 90.2 6.9 2e-25 90.2 4.8 2.0 2 0 0 2 2 2 1 TonB dependent receptor OMP_b-brl_3 PF14905.1 OAI96729.1 - 7e-06 25.0 0.6 0.00046 18.9 0.1 2.1 2 0 0 2 2 2 2 Outer membrane protein beta-barrel family LIP PF03583.9 OAI96732.1 - 1.9e-26 92.9 3.5 2.7e-26 92.4 2.4 1.2 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 OAI96732.1 - 0.0083 15.8 0.9 0.016 14.9 0.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family TPR_2 PF07719.12 OAI96733.1 - 7.8e-06 25.4 0.7 0.11 12.4 0.2 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAI96733.1 - 4e-05 23.8 15.5 0.19 12.4 0.0 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 OAI96733.1 - 4.5e-05 22.8 0.1 0.023 14.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAI96733.1 - 0.00038 20.0 0.0 0.19 11.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAI96733.1 - 0.00042 19.9 1.7 0.37 10.7 0.1 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAI96733.1 - 0.0018 17.8 1.3 1.9 8.1 0.0 2.7 2 1 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 OAI96733.1 - 0.0018 18.8 15.5 0.75 10.5 0.0 4.6 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAI96733.1 - 0.0088 15.9 10.7 0.28 11.1 0.2 3.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 OAI96733.1 - 0.028 14.8 17.9 4.6 7.9 0.0 5.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAI96733.1 - 0.26 11.8 1.8 29 5.4 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAI96733.1 - 1.1 9.6 9.7 12 6.3 0.2 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Cactin_mid PF10312.4 OAI96734.1 - 2e-10 40.2 0.3 2e-10 40.2 0.2 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin rve PF00665.21 OAI96739.1 - 2.8e-15 56.4 0.0 4.7e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Dfp1_Him1_M PF08630.5 OAI96740.1 - 0.012 15.3 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Dfp1/Him1, central region Erythro-docking PF09277.6 OAI96740.1 - 0.86 9.3 5.7 3.1 7.5 0.6 2.4 1 1 1 2 2 2 0 Erythronolide synthase, docking MULE PF10551.4 OAI96742.1 - 5.5e-08 32.8 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAI96742.1 - 0.061 11.8 0.1 0.091 11.2 0.1 1.1 1 0 0 1 1 1 0 Transposase, Mutator family Collagen PF01391.13 OAI96744.1 - 0.0004 19.8 2.6 0.00056 19.4 1.8 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) CAP18_C PF12153.3 OAI96744.1 - 0.11 12.1 1.2 0.23 11.1 0.8 1.5 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) DUF1910 PF08928.5 OAI96747.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) ABC_tran PF00005.22 OAI96750.1 - 7e-20 71.7 0.8 1.7e-19 70.4 0.0 2.1 3 0 0 3 3 3 1 ABC transporter ABC_trans_N PF14510.1 OAI96750.1 - 1.7e-07 31.2 0.1 4.1e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane PF01061.19 OAI96750.1 - 0.022 13.9 0.5 0.043 12.9 0.1 1.7 2 0 0 2 2 2 0 ABC-2 type transporter AAA_17 PF13207.1 OAI96750.1 - 0.05 14.4 0.0 0.13 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 OAI96750.1 - 0.068 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.1 OAI96750.1 - 0.07 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Meckelin PF09773.4 OAI96753.1 - 0.036 11.8 0.5 0.051 11.3 0.4 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) KxDL PF10241.4 OAI96753.1 - 0.074 12.9 5.0 0.15 11.9 3.5 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein Syntaxin_2 PF14523.1 OAI96753.1 - 0.53 10.3 8.8 8.1 6.5 2.3 2.8 2 1 0 2 2 2 0 Syntaxin-like protein LepA_C PF06421.7 OAI96756.1 - 0.079 12.8 0.3 0.079 12.8 0.2 1.8 2 1 0 2 2 2 0 GTP-binding protein LepA C-terminus Herpes_UL3 PF03369.8 OAI96756.1 - 0.65 9.9 3.6 3.9 7.4 0.8 2.2 1 1 0 2 2 2 0 Herpesvirus UL3 protein DUF3435 PF11917.3 OAI96756.1 - 0.83 8.2 7.5 1.1 7.8 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) HlyD_3 PF13437.1 OAI96774.1 - 0.048 14.0 0.0 0.065 13.5 0.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein eIF3_N PF09440.5 OAI96775.1 - 0.02 15.0 0.1 0.03 14.4 0.1 1.2 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain Avirulence PF03377.8 OAI96775.1 - 0.07 11.8 0.0 0.09 11.4 0.0 1.1 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA HhH-GPD PF00730.20 OAI96775.1 - 0.12 12.6 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein NKWYS PF10364.4 OAI96778.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein FHA PF00498.21 OAI96784.1 - 0.066 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 FHA domain Retrotrans_gag PF03732.12 OAI96788.1 - 0.061 13.4 0.2 0.061 13.4 0.2 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein TMF_DNA_bd PF12329.3 OAI96788.1 - 3.4 7.5 13.9 2 8.2 5.4 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Lipase_GDSL PF00657.17 OAI96790.1 - 3.2e-06 27.1 0.0 5.8e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 OAI96790.1 - 5.3e-05 23.4 0.1 7.6e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family RVT_1 PF00078.22 OAI96792.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.5 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pex14_N PF04695.8 OAI96793.1 - 0.18 11.8 2.9 0.14 12.1 0.4 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region rve PF00665.21 OAI96799.1 - 1.5e-21 76.6 0.0 3.2e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAI96799.1 - 1.3e-07 31.1 0.2 5.4e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 GAG-pre-integrase domain RVT_1 PF00078.22 OAI96804.1 - 1.4e-13 50.7 0.0 2.7e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 OAI96804.1 - 0.0036 17.0 0.0 0.0085 15.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAI96804.1 - 0.067 13.6 0.0 0.3 11.5 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease Fer4 PF00037.22 OAI96806.1 - 5.2e-15 54.3 16.3 7.9e-09 34.7 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 OAI96806.1 - 7.1e-13 48.7 10.8 1.1e-12 48.1 7.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 OAI96806.1 - 1.1e-10 41.0 23.2 2.4e-08 33.6 9.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 OAI96806.1 - 1.2e-10 41.9 7.7 2.7e-05 24.8 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 OAI96806.1 - 1.3e-10 40.9 5.1 2.9e-05 23.8 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 OAI96806.1 - 4.4e-10 39.4 29.7 6e-06 26.1 8.2 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.1 OAI96806.1 - 9.1e-10 38.6 11.2 1.9e-09 37.6 7.8 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 OAI96806.1 - 5.4e-09 35.4 14.6 4.4e-05 23.1 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 OAI96806.1 - 2e-08 33.7 18.0 0.00035 20.3 3.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 OAI96806.1 - 2.5e-07 30.9 28.5 0.00036 20.8 7.5 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 OAI96806.1 - 6.4e-07 29.2 12.1 0.00031 20.8 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 OAI96806.1 - 8.2e-06 26.1 10.6 0.0067 16.8 0.6 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 OAI96806.1 - 5.8e-05 23.3 12.0 0.02 15.2 0.5 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 OAI96806.1 - 0.0012 19.3 12.7 0.14 12.7 1.1 2.7 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 OAI96806.1 - 0.011 16.2 18.1 0.039 14.5 3.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 OAI96806.1 - 0.024 14.7 4.5 0.24 11.5 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_11 PF13247.1 OAI96806.1 - 0.027 14.3 3.7 0.04 13.7 2.6 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain 4HBT_3 PF13622.1 OAI96810.1 - 0.067 12.9 1.2 0.68 9.6 0.8 2.1 1 1 0 1 1 1 0 Thioesterase-like superfamily PPP4R2 PF09184.6 OAI96810.1 - 1.9 7.9 9.0 2.7 7.4 6.3 1.1 1 0 0 1 1 1 0 PPP4R2 DUF11 PF01345.13 OAI96810.1 - 3.1 7.8 6.0 31 4.7 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF11 DUF2051 PF09738.4 OAI96812.1 - 0.012 14.9 1.3 0.013 14.8 0.9 1.0 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Herpes_capsid PF06112.6 OAI96812.1 - 1 9.4 11.1 1.1 9.2 7.7 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Phage_integrase PF00589.17 OAI96817.1 - 1.3e-05 24.9 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family RVT_3 PF13456.1 OAI96818.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like GPS PF01825.16 OAI96818.1 - 0.17 11.9 2.7 0.58 10.3 1.9 1.9 1 1 0 1 1 1 0 Latrophilin/CL-1-like GPS domain adh_short PF00106.20 OAI96834.1 - 1.4e-07 31.5 0.0 2.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAI96834.1 - 0.021 14.4 0.1 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 KR domain zf-CCHC PF00098.18 OAI96837.1 - 0.00035 20.3 1.3 0.00035 20.3 0.9 1.9 2 0 0 2 2 2 1 Zinc knuckle SWIM PF04434.12 OAI96837.1 - 0.0015 17.9 0.9 0.004 16.6 0.6 1.7 1 0 0 1 1 1 1 SWIM zinc finger zf-CCHC_3 PF13917.1 OAI96837.1 - 0.057 13.1 0.3 0.057 13.1 0.2 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.1 OAI96837.1 - 0.22 11.0 5.1 0.13 11.7 1.6 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-ribbon_3 PF13248.1 OAI96837.1 - 1.1 8.5 4.6 0.28 10.4 0.2 2.0 2 0 0 2 2 2 0 zinc-ribbon domain DBD_Tnp_Mut PF03108.10 OAI96838.1 - 6.4e-11 41.6 0.1 1.1e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 MuDR family transposase PQQ PF01011.16 OAI96840.1 - 0.089 12.3 0.5 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_2 PF13360.1 OAI96840.1 - 0.16 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain Frag1 PF10277.4 OAI96842.1 - 6.4e-26 91.1 14.2 8.9e-26 90.6 9.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family CTP_transf_1 PF01148.15 OAI96842.1 - 1.1 8.9 10.0 2 7.9 6.9 1.6 1 1 0 1 1 1 0 Cytidylyltransferase family E1-E2_ATPase PF00122.15 OAI96842.1 - 4.9 6.1 7.8 11 4.9 5.4 1.6 1 1 0 1 1 1 0 E1-E2 ATPase rve PF00665.21 OAI96853.1 - 1.9e-14 53.7 0.0 4.9e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAI96853.1 - 1.7e-06 27.5 0.0 4.5e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-FPG_IleRS PF06827.9 OAI96868.1 - 0.00022 20.7 8.4 0.00038 20.0 5.8 1.3 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS DZR PF12773.2 OAI96868.1 - 0.083 12.7 1.0 0.14 12.0 0.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 OAI96868.1 - 0.11 12.1 0.3 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Mpv17_PMP22 PF04117.7 OAI96869.1 - 7.1e-25 86.4 3.5 1.3e-24 85.5 2.4 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family BBE PF08031.7 OAI96871.1 - 0.00028 20.7 0.2 0.0004 20.2 0.1 1.2 1 0 0 1 1 1 1 Berberine and berberine like PIN_4 PF13638.1 OAI96872.1 - 1.2e-09 38.4 0.0 1.8e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 PIN domain EF-hand_10 PF14788.1 OAI96880.1 - 0.011 15.3 0.1 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 EF hand ORC6 PF05460.8 OAI96885.1 - 0.004 16.3 2.1 0.004 16.3 1.5 1.8 2 0 0 2 2 2 1 Origin recognition complex subunit 6 (ORC6) DUF2798 PF11391.3 OAI96889.1 - 0.053 13.2 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) CPT PF07931.7 OAI96892.1 - 0.098 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Glyco_hydro_45 PF02015.11 OAI96893.1 - 8.2e-17 61.9 0.0 9.7e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 DUF4604 PF15377.1 OAI96895.1 - 0.034 14.3 1.0 0.047 13.9 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF1176 PF06674.6 OAI96895.1 - 0.086 11.9 0.0 0.097 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) AIRC PF00731.15 OAI96897.1 - 7.8e-07 28.4 0.0 9e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 AIR carboxylase DUF330 PF03886.8 OAI96897.1 - 0.15 11.4 0.0 0.17 11.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF330) MRP-L47 PF06984.8 OAI96901.1 - 0.00034 20.4 2.2 0.00073 19.3 1.5 1.6 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.18 OAI96901.1 - 0.0093 15.6 0.3 0.016 14.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal L29 protein Proteasome PF00227.21 OAI96902.1 - 3.6e-21 75.2 0.1 8.1e-21 74.1 0.0 1.5 2 0 0 2 2 2 1 Proteasome subunit Pr_beta_C PF12465.3 OAI96902.1 - 1.6e-06 27.2 0.1 3e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Proteasome PF00227.21 OAI96904.1 - 2e-50 170.7 0.2 2.7e-50 170.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit DUF2188 PF09954.4 OAI96904.1 - 0.0019 18.0 0.3 0.072 13.0 0.1 2.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2188) Yos1 PF08571.5 OAI96907.1 - 5.5e-28 96.8 1.4 7e-28 96.5 1.0 1.1 1 0 0 1 1 1 1 Yos1-like CH PF00307.26 OAI96908.1 - 2.4e-07 30.7 0.1 2.8e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain GMC_oxred_C PF05199.8 OAI96913.1 - 2.1e-37 128.6 0.0 3.6e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 OAI96913.1 - 1.5e-22 80.1 0.0 2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase RVT_1 PF00078.22 OAI96919.1 - 1.3e-10 41.0 0.0 3.1e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAI96922.1 - 2.4e-23 82.6 0.0 3.8e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HAD_2 PF13419.1 OAI96925.1 - 1.8e-09 38.0 0.0 4.3e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAI96925.1 - 8.7e-05 23.0 0.0 0.00028 21.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAI96925.1 - 0.0082 16.3 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase p450 PF00067.17 OAI96932.1 - 1.2e-13 50.4 0.0 1.4e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FUSC PF04632.7 OAI96944.1 - 0.22 9.9 0.9 0.29 9.5 0.5 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF3347 PF11827.3 OAI96944.1 - 1 9.3 6.3 0.34 10.9 2.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) RVT_1 PF00078.22 OAI96955.1 - 0.17 11.2 0.0 0.44 9.8 0.0 1.6 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAI96957.1 - 6.8e-06 26.4 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 RNase H DnaJ PF00226.26 OAI96957.1 - 0.00044 19.9 0.0 0.0015 18.2 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Sec62 PF03839.11 OAI96957.1 - 0.092 12.1 0.4 0.14 11.5 0.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DDHD PF02862.12 OAI96957.1 - 0.99 9.1 5.4 1.3 8.7 3.8 1.1 1 0 0 1 1 1 0 DDHD domain DUF1703 PF08011.6 OAI96957.1 - 2 8.1 6.9 10 5.8 5.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1703) CDC45 PF02724.9 OAI96957.1 - 5.5 4.8 9.0 6.7 4.6 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein LRS4 PF10422.4 OAI96960.1 - 0.58 9.4 3.6 0.67 9.2 2.5 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 SpoIID PF08486.5 OAI96960.1 - 2 8.7 5.1 2.6 8.4 3.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein DHquinase_II PF01220.14 OAI96963.1 - 5.6e-35 119.6 0.0 7.5e-35 119.2 0.0 1.2 1 0 0 1 1 1 1 Dehydroquinase class II PCNA_N PF00705.13 OAI96963.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain DHquinase_II PF01220.14 OAI96964.1 - 1.3e-31 108.8 0.1 1.4e-31 108.7 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II LRR_8 PF13855.1 OAI96965.1 - 6.9e-05 22.5 1.1 6.9e-05 22.5 0.8 1.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 OAI96965.1 - 8.1e-05 22.1 3.8 0.0036 16.8 0.3 2.8 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 OAI96965.1 - 0.0005 19.7 0.8 1.2 9.4 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 OAI96965.1 - 0.43 10.9 6.8 1.5 9.3 0.0 3.3 3 0 0 3 3 3 0 Leucine rich repeat Na_Ca_ex PF01699.19 OAI96968.1 - 2.4e-16 59.6 3.1 3.1e-16 59.2 2.1 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Astro_capsid PF03115.9 OAI96976.1 - 0.07 11.3 2.1 0.16 10.1 0.7 1.9 1 1 1 2 2 2 0 Astrovirus capsid protein precursor Daxx PF03344.10 OAI96976.1 - 2.4 6.5 11.9 3.6 5.9 8.2 1.2 1 0 0 1 1 1 0 Daxx Family COPI_C PF06957.6 OAI96976.1 - 6.6 5.1 6.7 10 4.4 4.7 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus BDV_G PF06208.6 OAI96979.1 - 0.066 12.1 0.1 0.074 11.9 0.0 1.0 1 0 0 1 1 1 0 Borna disease virus G protein DUF2722 PF10846.3 OAI96979.1 - 0.18 10.8 5.5 0.18 10.7 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nucleoporin_FG PF13634.1 OAI96981.1 - 1.7 8.8 11.8 0.12 12.5 4.5 1.7 2 0 0 2 2 2 0 Nucleoporin FG repeat region KAR9 PF08580.5 OAI96990.1 - 1.7 6.8 11.0 1.8 6.7 0.1 2.1 1 1 0 2 2 2 0 Yeast cortical protein KAR9 MitMem_reg PF13012.1 OAI96995.1 - 4.8e-20 71.7 0.0 8.5e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 OAI96995.1 - 6.9e-17 61.2 0.0 1.5e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DDE_Tnp_4 PF13359.1 OAI96998.1 - 1e-15 57.6 0.0 1.2e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease COG5 PF10392.4 OAI96999.1 - 0.011 15.6 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Myb_DNA-bind_5 PF13873.1 OAI96999.1 - 0.014 15.3 0.1 0.045 13.6 0.1 1.8 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAI96999.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain CDC45 PF02724.9 OAI96999.1 - 0.11 10.5 2.9 0.13 10.2 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 OAI96999.1 - 0.14 10.0 11.7 0.2 9.5 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 OAI96999.1 - 0.18 10.8 8.1 0.22 10.5 5.6 1.1 1 0 0 1 1 1 0 BUD22 FYDLN_acid PF09538.5 OAI96999.1 - 0.55 10.8 15.6 0.99 10.0 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TFIIF_alpha PF05793.7 OAI96999.1 - 0.78 8.0 12.8 1.1 7.6 8.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.7 OAI96999.1 - 9 5.4 15.0 12 5.0 10.4 1.1 1 0 0 1 1 1 0 SDA1 SWIM PF04434.12 OAI97002.1 - 0.035 13.5 0.1 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 SWIM zinc finger Glyco_transf_20 PF00982.16 OAI97005.1 - 2.1e-124 415.6 0.0 2.7e-124 415.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 OAI97005.1 - 0.047 13.1 0.1 10 5.4 0.0 2.5 2 1 0 2 2 2 0 Glycosyl transferases group 1 RVT_1 PF00078.22 OAI97007.1 - 3.9e-16 59.0 0.0 9.7e-16 57.7 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.5 OAI97016.1 - 0.01 14.9 4.2 0.014 14.4 2.9 1.2 1 0 0 1 1 1 0 BUD22 RTC_insert PF05189.8 OAI97016.1 - 0.019 14.9 0.2 0.039 13.9 0.1 1.5 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain DBD_Tnp_Hermes PF10683.4 OAI97016.1 - 0.13 11.7 0.1 0.38 10.2 0.0 1.8 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain PP2C PF00481.16 OAI97021.1 - 1.2e-82 277.1 0.0 1.9e-82 276.5 0.0 1.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 OAI97021.1 - 0.00061 19.2 0.0 0.0016 17.8 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C TPR_12 PF13424.1 OAI97024.1 - 9e-08 31.9 1.8 0.00018 21.4 0.2 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAI97024.1 - 1.8e-07 30.8 2.4 2.7e-06 27.0 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAI97024.1 - 0.00026 20.6 0.3 0.044 13.7 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAI97024.1 - 0.011 15.4 0.5 0.92 9.4 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3366 PF11846.3 OAI97024.1 - 0.023 14.5 0.4 0.6 9.9 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3366) TPR_15 PF13429.1 OAI97024.1 - 0.023 13.7 1.0 0.38 9.7 0.5 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 OAI97024.1 - 0.051 13.2 0.8 0.1 12.2 0.6 1.6 1 1 0 1 1 1 0 TPR repeat TPR_4 PF07721.9 OAI97024.1 - 0.067 13.6 0.4 19 6.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAI97024.1 - 0.13 13.0 2.5 1.3 9.8 0.2 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 OAI97024.1 - 0.13 12.4 0.2 20 5.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAI97024.1 - 0.24 11.2 1.2 2.7 8.0 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAI97024.1 - 0.42 11.3 2.7 1.7 9.3 1.9 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat DEDD_Tnp_IS110 PF01548.12 OAI97028.1 - 1.8e-20 73.0 0.0 2.8e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Transposase Transposase_20 PF02371.11 OAI97028.1 - 1e-18 67.2 0.0 2.3e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family HHH_5 PF14520.1 OAI97028.1 - 0.047 13.8 0.0 0.24 11.5 0.0 2.2 2 1 0 2 2 2 0 Helix-hairpin-helix domain DUF3321 PF11968.3 OAI97032.1 - 6.1e-44 150.2 0.0 5.3e-26 91.6 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase (DUF3321) DUF387 PF04079.11 OAI97034.1 - 0.095 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) CTP_transf_1 PF01148.15 OAI97050.1 - 1.4e-11 44.5 7.7 5.3e-09 36.1 2.6 2.8 1 1 1 2 2 2 2 Cytidylyltransferase family Transposase_21 PF02992.9 OAI97052.1 - 8.2e-14 51.2 0.4 1.8e-13 50.1 0.0 1.6 2 0 0 2 2 2 1 Transposase family tnp2 zf-Di19 PF05605.7 OAI97054.1 - 0.16 12.1 1.5 1.8 8.7 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PRP21_like_P PF12230.3 OAI97054.1 - 7.1 6.0 9.1 13 5.2 4.4 2.0 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein DUF4218 PF13960.1 OAI97057.1 - 6.4e-05 22.3 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF605 PF04652.11 OAI97061.1 - 3.3 6.9 6.8 5.5 6.2 4.7 1.4 1 0 0 1 1 1 0 Vta1 like zf-BED PF02892.10 OAI97065.1 - 0.091 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 BED zinc finger Senescence_reg PF04520.8 OAI97065.1 - 0.55 10.7 2.9 0.86 10.0 2.0 1.3 1 0 0 1 1 1 0 Senescence regulator RVT_3 PF13456.1 OAI97068.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Sec1 PF00995.18 OAI97071.1 - 1.5e-98 330.8 0.0 2.9e-98 329.9 0.0 1.3 1 1 0 1 1 1 1 Sec1 family YlbD_coat PF14071.1 OAI97071.1 - 0.027 14.5 0.1 0.027 14.5 0.1 2.1 2 0 0 2 2 2 0 Putative coat protein Mito_carr PF00153.22 OAI97074.1 - 8.3e-64 211.3 2.5 9.8e-20 70.0 0.0 4.6 3 1 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 OAI97074.1 - 0.016 15.0 0.3 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 UcrQ family DUF164 PF02591.10 OAI97074.1 - 0.12 12.1 0.0 0.46 10.3 0.0 2.0 1 0 0 1 1 1 0 Putative zinc ribbon domain MULE PF10551.4 OAI97080.1 - 1.2e-19 70.2 0.0 2.6e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAI97080.1 - 5.9e-11 41.5 0.1 1e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family GAGA_bind PF06217.7 OAI97082.1 - 7.5 6.4 29.8 2.7 7.8 17.5 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family Herpes_UL87 PF03043.9 OAI97082.1 - 9.2 4.5 16.5 20 3.4 11.5 1.5 1 0 0 1 1 1 0 Herpesvirus UL87 family HSP70 PF00012.15 OAI97086.1 - 8.9e-11 40.4 1.2 2.9e-07 28.7 0.2 2.0 1 1 1 2 2 2 2 Hsp70 protein Peptidase_C48 PF02902.14 OAI97092.1 - 6.3e-08 32.5 0.5 5.4e-07 29.4 0.0 2.4 1 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain WD40 PF00400.27 OAI97093.1 - 5.5e-05 22.8 17.7 0.057 13.3 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoplasmin PF03066.10 OAI97093.1 - 0.13 11.7 2.3 0.21 11.0 1.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 OAI97093.1 - 0.31 11.2 8.8 0.74 10.0 6.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Tannase PF07519.6 OAI97095.1 - 1.1e-28 100.2 0.1 1.3e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase MT-A70 PF05063.9 OAI97098.1 - 2e-07 30.7 0.0 0.0072 15.9 0.1 3.4 2 1 0 2 2 2 2 MT-A70 HSP70 PF00012.15 OAI97100.1 - 4.8e-07 28.0 0.1 5.9e-07 27.7 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein Cro PF09048.5 OAI97103.1 - 0.051 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Cro FAM47 PF14642.1 OAI97104.1 - 8.6 5.5 13.7 1.1 8.4 2.8 2.0 1 1 1 2 2 2 0 FAM47 family RNase_H PF00075.19 OAI97106.1 - 0.00099 19.4 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAI97106.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like TFIIB PF00382.14 OAI97106.1 - 0.11 12.3 0.0 3.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Phage_int_SAM_1 PF02899.12 OAI97107.1 - 0.0024 17.9 0.0 0.0045 17.1 0.0 1.5 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain MIP PF00230.15 OAI97113.1 - 0.046 13.1 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Major intrinsic protein RdRP_2 PF00978.16 OAI97115.1 - 1e-13 50.7 0.0 1.3e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Serpin PF00079.15 OAI97115.1 - 0.014 14.5 0.1 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) ORC6 PF05460.8 OAI97119.1 - 0.0074 15.4 2.7 0.013 14.6 1.9 1.4 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Ets PF00178.17 OAI97119.1 - 0.042 14.0 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Ets-domain Nop14 PF04147.7 OAI97127.1 - 0.018 13.0 23.4 0.02 12.8 16.3 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 OAI97127.1 - 0.05 12.0 11.3 0.063 11.7 7.8 1.2 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 OAI97127.1 - 0.12 11.6 19.9 0.18 11.0 13.8 1.3 1 0 0 1 1 1 0 NOA36 protein Myb_DNA-bind_5 PF13873.1 OAI97127.1 - 0.13 12.1 0.0 0.84 9.5 0.0 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain SDA1 PF05285.7 OAI97127.1 - 0.83 8.8 21.7 1.2 8.3 15.0 1.3 1 0 0 1 1 1 0 SDA1 DUF1510 PF07423.6 OAI97127.1 - 1.1 8.6 9.5 1.6 8.0 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Glypican PF01153.14 OAI97127.1 - 2.5 6.5 5.5 3 6.3 3.8 1.1 1 0 0 1 1 1 0 Glypican SAPS PF04499.10 OAI97127.1 - 2.7 6.5 4.2 3.3 6.2 2.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Atrophin-1 PF03154.10 OAI97127.1 - 4 5.4 12.4 4.5 5.2 8.6 1.0 1 0 0 1 1 1 0 Atrophin-1 family TFIIA PF03153.8 OAI97127.1 - 5 6.9 28.0 7.5 6.3 19.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RPA PF10134.4 OAI97132.1 - 1.7e-14 53.6 0.0 2.1e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Replication initiator protein A Tash_PEST PF07708.6 OAI97132.1 - 3.3 7.7 4.9 7.8 6.5 0.5 2.4 2 0 0 2 2 2 0 Tash protein PEST motif Astro_capsid PF03115.9 OAI97141.1 - 0.00051 18.4 0.4 0.00067 18.0 0.3 1.1 1 0 0 1 1 1 1 Astrovirus capsid protein precursor Ax_dynein_light PF10211.4 OAI97141.1 - 0.39 10.5 7.0 0.72 9.6 4.8 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain Catalase PF00199.14 OAI97142.1 - 3.7e-27 94.9 0.3 4.1e-27 94.8 0.2 1.0 1 0 0 1 1 1 1 Catalase BATS PF06968.8 OAI97146.1 - 3.1e-26 91.0 0.1 1.2e-25 89.1 0.0 2.1 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 OAI97146.1 - 3.5e-13 50.0 0.1 5.7e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Motile_Sperm PF00635.21 OAI97149.1 - 0.081 12.5 0.2 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 MSP (Major sperm protein) domain FHA PF00498.21 OAI97151.1 - 0.064 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 FHA domain TIP120 PF08623.5 OAI97155.1 - 0.12 11.9 1.1 0.15 11.5 0.8 1.3 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) DDHD PF02862.12 OAI97155.1 - 0.42 10.3 5.1 0.6 9.8 3.5 1.3 1 0 0 1 1 1 0 DDHD domain RVT_3 PF13456.1 OAI97160.1 - 0.056 13.2 0.1 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like HTH_40 PF14493.1 OAI97168.1 - 0.073 13.3 0.0 0.16 12.2 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain Phage_integrase PF00589.17 OAI97170.1 - 0.0093 15.6 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_integrase PF00589.17 OAI97185.1 - 1.2e-22 80.4 0.0 4.5e-22 78.5 0.0 1.8 2 0 0 2 2 2 1 Phage integrase family DUF4102 PF13356.1 OAI97185.1 - 5.9e-15 54.9 1.5 2e-14 53.2 1.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4102) MCM PF00493.18 OAI97191.1 - 6.7e-43 146.7 0.0 7.9e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 OAI97191.1 - 0.00045 19.4 0.0 0.0011 18.1 0.0 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI FYVE PF01363.16 OAI97197.1 - 6.1e-11 42.0 4.4 1.1e-10 41.2 3.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger Preseq_ALAS PF09029.5 OAI97198.1 - 0.11 12.5 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence Pkinase PF00069.20 OAI97200.1 - 3e-24 85.5 0.0 4.8e-18 65.2 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAI97200.1 - 1e-10 41.1 0.0 5.6e-08 32.1 0.0 3.2 1 1 0 1 1 1 1 Protein tyrosine kinase Sec23_trunk PF04811.10 OAI97205.1 - 9.1e-72 241.3 0.0 1.5e-71 240.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.10 OAI97205.1 - 5.5e-17 61.0 7.9 1e-16 60.1 5.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 OAI97205.1 - 1.6e-16 59.5 0.1 3.6e-16 58.4 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 OAI97205.1 - 1.5e-07 31.7 0.0 4.6e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain DUF948 PF06103.6 OAI97210.1 - 0.01 15.6 1.4 6.5 6.6 0.1 4.5 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) BBP1_C PF15272.1 OAI97210.1 - 0.3 10.6 10.3 1.2 8.7 2.1 2.6 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal DUF4618 PF15397.1 OAI97210.1 - 0.31 10.3 11.3 0.073 12.3 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) RVP_2 PF08284.6 OAI97212.1 - 6.2e-07 29.4 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_3 PF13917.1 OAI97212.1 - 0.00019 21.1 0.1 0.00042 19.9 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 OAI97212.1 - 0.00026 20.7 2.3 0.00051 19.8 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 OAI97212.1 - 0.00047 19.7 0.4 0.0012 18.5 0.2 1.6 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 OAI97212.1 - 0.0068 16.8 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI97212.1 - 0.009 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 OAI97212.1 - 0.026 14.5 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein RVP PF00077.15 OAI97212.1 - 0.054 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_4 PF14392.1 OAI97212.1 - 0.12 12.0 0.2 0.23 11.1 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Herpes_LMP2 PF07415.6 OAI97212.1 - 6.5 5.2 4.9 12 4.2 3.4 1.4 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein VID27 PF08553.5 OAI97216.1 - 3.8e-120 402.4 0.1 4.6e-120 402.2 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Methyltransf_PK PF05891.7 OAI97219.1 - 3.8e-49 166.9 0.0 9.1e-16 57.8 0.0 4.2 3 1 0 3 3 3 3 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 OAI97219.1 - 3.7e-05 23.5 0.0 0.00028 20.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAI97219.1 - 0.00023 21.6 0.1 0.016 15.7 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAI97219.1 - 0.0011 19.4 0.0 1.1 9.7 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 OAI97219.1 - 0.029 14.7 0.0 7 7.0 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain MRVI1 PF05781.7 OAI97219.1 - 0.083 11.2 0.0 0.083 11.2 0.0 1.8 2 0 0 2 2 2 0 MRVI1 protein Methyltransf_2 PF00891.13 OAI97219.1 - 0.097 11.8 0.0 0.24 10.5 0.0 1.7 1 0 0 1 1 1 0 O-methyltransferase Ras PF00071.17 OAI97224.1 - 4.9e-05 22.7 0.0 6.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Ras family DNA_ligase_OB_2 PF14743.1 OAI97224.1 - 0.00015 21.3 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 DNA ligase OB-like domain Transglut_core3 PF13471.1 OAI97228.1 - 4.6e-18 65.1 0.3 5.3e-18 64.9 0.2 1.0 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_core PF01841.14 OAI97228.1 - 0.0033 17.6 0.1 0.0041 17.3 0.1 1.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF2921 PF11145.3 OAI97228.1 - 0.11 10.2 0.0 0.11 10.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) Transposase_21 PF02992.9 OAI97234.1 - 2.8e-15 56.0 0.0 5.5e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Melittin PF01372.12 OAI97237.1 - 0.023 14.0 0.2 0.047 13.0 0.1 1.5 1 0 0 1 1 1 0 Melittin RVT_1 PF00078.22 OAI97239.1 - 7.1e-16 58.2 0.0 1.4e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) COesterase PF00135.23 OAI97241.1 - 4.6e-32 111.4 0.0 5.5e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAI97241.1 - 1.9e-05 24.3 0.1 3.3e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold SAC3_GANP PF03399.11 OAI97252.1 - 0.0053 16.3 0.1 0.0074 15.8 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family NUDIX PF00293.23 OAI97253.1 - 5.8e-28 97.2 0.0 8.9e-28 96.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain FA_desaturase PF00487.19 OAI97262.1 - 0.073 12.4 0.1 0.094 12.1 0.1 1.1 1 0 0 1 1 1 0 Fatty acid desaturase FAD_binding_2 PF00890.19 OAI97267.1 - 1.6e-48 165.6 0.1 1.9e-48 165.3 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAI97267.1 - 2.2e-14 53.1 1.1 2.7e-13 49.5 0.7 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAI97267.1 - 3.5e-11 42.9 0.6 4.5e-10 39.4 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAI97267.1 - 3.2e-09 36.9 0.4 9.4e-08 32.1 0.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAI97267.1 - 2e-07 30.4 0.7 3.4e-07 29.6 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 OAI97267.1 - 3.9e-07 28.8 0.1 2.4e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 OAI97267.1 - 6.4e-07 28.5 0.8 0.00095 18.1 0.2 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 OAI97267.1 - 2.4e-06 26.8 0.9 4.6e-06 25.9 0.6 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 OAI97267.1 - 3.5e-05 23.9 0.1 5.4e-05 23.3 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAI97267.1 - 0.00018 20.7 1.0 0.00029 20.0 0.2 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 OAI97267.1 - 0.00037 20.8 0.7 0.0022 18.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 OAI97267.1 - 0.00055 19.1 0.0 0.0012 17.9 0.0 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 OAI97267.1 - 0.00067 19.4 0.1 0.075 12.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 OAI97267.1 - 0.0083 15.7 0.1 0.018 14.5 0.0 1.6 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 OAI97267.1 - 0.0089 16.2 0.0 0.02 15.1 0.0 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding GDI PF00996.13 OAI97267.1 - 0.0097 14.2 0.1 0.014 13.7 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor Lycopene_cycl PF05834.7 OAI97267.1 - 0.011 14.6 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 OAI97267.1 - 0.07 13.1 0.2 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.13 OAI97267.1 - 0.078 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CRAL_TRIO PF00650.15 OAI97270.1 - 6.1e-14 51.8 0.0 1.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAI97270.1 - 2.5e-13 49.9 1.0 5.1e-13 48.9 0.7 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 OAI97270.1 - 0.034 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 OAI97271.1 - 0.01 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain PCI PF01399.22 OAI97275.1 - 0.025 14.8 0.0 0.032 14.5 0.0 1.2 1 0 0 1 1 1 0 PCI domain RVT_3 PF13456.1 OAI97279.1 - 0.036 13.8 0.0 0.097 12.4 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like Transposase_21 PF02992.9 OAI97284.1 - 8.3e-11 41.4 0.0 1.8e-10 40.2 0.0 1.5 2 0 0 2 2 2 1 Transposase family tnp2 FAD_binding_4 PF01565.18 OAI97289.1 - 4.2e-21 74.8 0.5 6.6e-21 74.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAI97289.1 - 0.0019 18.0 0.3 0.0042 16.9 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like RVT_3 PF13456.1 OAI97292.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like Phage_integrase PF00589.17 OAI97293.1 - 3.4e-06 26.8 0.0 6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family MFS_1 PF07690.11 OAI97300.1 - 8.9e-33 113.4 57.7 5.3e-19 68.1 19.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAI97300.1 - 0.65 8.3 33.2 0.03 12.7 7.8 3.2 1 1 2 3 3 3 0 MFS/sugar transport protein Fer2 PF00111.22 OAI97301.1 - 9.7e-14 50.8 0.8 1.2e-13 50.6 0.6 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1364 PF07102.7 OAI97301.1 - 0.035 13.9 0.4 0.042 13.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) Pyr_redox_2 PF07992.9 OAI97302.1 - 3.1e-09 37.0 0.0 3.3e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAI97302.1 - 0.00025 20.0 0.0 0.00031 19.7 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAI97302.1 - 0.011 15.7 0.2 0.019 15.0 0.1 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAI97302.1 - 0.017 15.2 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAI97302.1 - 0.031 14.6 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAI97302.1 - 0.043 12.8 0.1 0.058 12.4 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 OAI97302.1 - 0.059 13.1 0.1 0.1 12.3 0.1 1.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 OAI97302.1 - 0.061 13.3 0.1 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.16 OAI97302.1 - 0.068 13.0 0.2 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 ThiF family Trp_halogenase PF04820.9 OAI97302.1 - 0.093 11.3 0.1 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.1 OAI97302.1 - 0.12 11.2 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_10 PF13460.1 OAI97302.1 - 0.13 12.2 0.3 0.2 11.6 0.1 1.4 1 1 0 1 1 1 0 NADH(P)-binding 4HB_MCP_1 PF12729.2 OAI97303.1 - 0.00025 20.4 0.6 0.00054 19.3 0.4 1.6 1 1 0 1 1 1 1 Four helix bundle sensory module for signal transduction TarH PF02203.10 OAI97303.1 - 0.042 13.6 2.0 0.059 13.2 1.4 1.4 1 1 0 1 1 1 0 Tar ligand binding domain homologue DUF4381 PF14316.1 OAI97303.1 - 0.058 13.4 0.1 0.071 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF641 PF04859.7 OAI97303.1 - 0.072 12.8 0.4 0.095 12.4 0.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) HNH_2 PF13391.1 OAI97307.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.4 1 1 0 1 1 1 0 HNH endonuclease HSP33 PF01430.14 OAI97311.1 - 0.16 11.0 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Hsp33 protein DUF202 PF02656.10 OAI97312.1 - 0.049 13.8 0.6 0.11 12.7 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF202) AMMECR1 PF01871.12 OAI97315.1 - 8.3e-42 142.2 0.0 1.1e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 rve PF00665.21 OAI97318.1 - 4.8e-21 75.0 0.0 1e-20 74.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain UBN2_2 PF14227.1 OAI97318.1 - 4.5e-14 52.0 0.0 8.1e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAI97318.1 - 5.5e-09 35.8 0.1 1.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAI97318.1 - 1.1e-06 28.3 1.9 1.1e-06 28.3 1.3 1.8 2 0 0 2 2 2 1 Zinc knuckle gag_pre-integrs PF13976.1 OAI97318.1 - 1.4e-06 27.8 0.0 2.9e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAI97318.1 - 0.00042 19.7 0.1 0.0014 18.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain UBN2_3 PF14244.1 OAI97318.1 - 0.048 13.2 0.1 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 OAI97318.1 - 0.39 10.4 2.8 0.35 10.5 0.4 2.1 2 0 0 2 2 2 0 Zinc knuckle DUF2664 PF10867.3 OAI97321.1 - 0.016 15.8 4.8 0.029 14.9 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) LcrV PF04792.7 OAI97321.1 - 0.031 13.3 0.7 0.041 12.8 0.5 1.1 1 0 0 1 1 1 0 V antigen (LcrV) protein DUF572 PF04502.8 OAI97321.1 - 0.87 8.7 5.3 1 8.5 3.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DEAD PF00270.24 OAI97323.1 - 1.1e-09 37.9 0.0 2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAI97323.1 - 1.1e-08 34.8 0.0 1.7e-07 31.0 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAI97323.1 - 0.002 18.0 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 OAI97323.1 - 0.039 13.5 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 OAI97323.1 - 0.074 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.12 OAI97323.1 - 0.078 12.7 0.0 5.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 Nop53 PF07767.6 OAI97336.1 - 3.9 6.3 16.8 4.5 6.1 11.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TFIIF_alpha PF05793.7 OAI97336.1 - 6.7 4.9 29.5 7.7 4.7 20.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-T PF15511.1 OAI97336.1 - 10 5.2 16.9 10 5.2 11.7 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T rve PF00665.21 OAI97340.1 - 3.4e-16 59.4 0.0 6.4e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RRM_1 PF00076.17 OAI97345.1 - 7.6e-37 124.7 0.0 6.4e-16 57.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAI97345.1 - 9e-21 73.6 0.0 1.4e-07 31.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAI97345.1 - 8.6e-07 28.7 0.0 0.0062 16.3 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAPS PF04499.10 OAI97345.1 - 0.16 10.5 8.3 0.28 9.7 5.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 OAI97345.1 - 0.2 9.5 31.8 0.32 8.8 22.0 1.3 1 0 0 1 1 1 0 Nop14-like family Nha1_C PF08619.5 OAI97345.1 - 0.74 9.0 28.4 0.03 13.6 15.5 1.6 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus BUD22 PF09073.5 OAI97345.1 - 4 6.3 33.1 9.4 5.1 22.9 1.5 1 0 0 1 1 1 0 BUD22 Gly-zipper_OmpA PF13436.1 OAI97348.1 - 0.00071 19.2 1.1 0.0014 18.2 0.8 1.5 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain DUF1269 PF06897.7 OAI97348.1 - 0.089 12.8 0.1 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) RGS PF00615.14 OAI97350.1 - 1.4e-05 25.1 0.0 2.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Ribosomal_L37e PF01907.14 OAI97353.1 - 0.11 12.2 0.3 0.16 11.8 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein L37e Phage_int_SAM_1 PF02899.12 OAI97355.1 - 0.0093 16.0 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 OAI97355.1 - 0.029 14.7 0.0 0.05 13.9 0.0 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF1528 PF07515.6 OAI97361.1 - 3.3e-37 126.7 0.0 5.1e-37 126.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1528) PMT_2 PF13231.1 OAI97361.1 - 1.5e-18 67.2 16.5 1.5e-18 67.2 11.4 3.1 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.13 OAI97361.1 - 2.2e-13 50.1 16.5 5.5e-13 48.8 11.4 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase RP-C_C PF11800.3 OAI97369.1 - 6e-86 287.4 0.0 1e-85 286.6 0.0 1.4 1 0 0 1 1 1 1 Replication protein C C-terminal region RP-C PF03428.8 OAI97369.1 - 5.7e-76 253.8 1.2 9.3e-76 253.2 0.8 1.3 1 0 0 1 1 1 1 Replication protein C N-terminal domain HTH_20 PF12840.2 OAI97369.1 - 0.00014 21.5 0.3 0.004 16.9 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.2 OAI97369.1 - 0.00026 20.5 0.1 0.0011 18.5 0.1 2.1 1 0 0 1 1 1 1 MarR family MarR PF01047.17 OAI97369.1 - 0.002 17.8 0.2 0.024 14.3 0.0 2.4 2 0 0 2 2 2 1 MarR family HTH_5 PF01022.15 OAI97369.1 - 0.0083 15.7 0.4 0.04 13.5 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 OAI97369.1 - 0.028 13.8 0.0 0.09 12.1 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_36 PF13730.1 OAI97369.1 - 0.029 14.4 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_27 PF13463.1 OAI97369.1 - 0.047 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_IclR PF09339.5 OAI97369.1 - 0.078 12.5 2.1 0.85 9.2 1.4 2.5 1 1 0 1 1 1 0 IclR helix-turn-helix domain HTH_DeoR PF08220.7 OAI97369.1 - 0.16 11.5 0.6 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain TPR_14 PF13428.1 OAI97369.1 - 1.4 9.7 11.3 6.7 7.6 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Histone PF00125.19 OAI97372.1 - 1.5e-29 101.9 0.6 2.3e-29 101.3 0.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAI97372.1 - 3.4e-05 23.9 0.0 5.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAI97372.1 - 0.024 14.6 1.1 0.028 14.4 0.1 1.5 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 OAI97372.1 - 0.13 12.0 0.1 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Mucin PF01456.12 OAI97374.1 - 7.9e-05 22.4 17.3 0.00015 21.5 10.7 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein Peptidase_S24 PF00717.18 OAI97374.1 - 0.14 11.8 0.1 0.63 9.7 0.0 2.1 3 0 0 3 3 3 0 Peptidase S24-like Abhydrolase_6 PF12697.2 OAI97379.1 - 9.4e-24 84.5 4.4 1.3e-23 84.0 3.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAI97379.1 - 1.9e-14 53.6 0.9 4.7e-14 52.3 0.6 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAI97379.1 - 3.1e-11 43.2 0.0 3.9e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAI97379.1 - 1.1e-06 28.3 0.1 1.1e-06 28.3 0.1 2.2 2 1 1 3 3 3 1 Putative lysophospholipase Asp PF00026.18 OAI97381.1 - 4.9e-53 180.4 0.8 6.4e-53 180.0 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 OAI97381.1 - 3.2e-05 23.5 0.0 0.00012 21.7 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 OAI97381.1 - 0.25 11.2 3.6 0.13 12.1 0.5 2.1 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal Asp PF00026.18 OAI97382.1 - 5.2e-05 22.6 0.1 8.1e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Sensor PF13796.1 OAI97389.1 - 0.77 9.3 6.7 0.31 10.6 0.2 2.2 2 0 0 2 2 2 0 Putative sensor DDE_Tnp_4 PF13359.1 OAI97392.1 - 1.3e-28 99.5 0.0 1.9e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAI97392.1 - 7.5e-06 25.4 0.0 0.00012 21.4 0.0 2.1 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.16 OAI97392.1 - 0.00026 20.6 0.0 0.0009 18.8 0.0 1.8 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.1 OAI97392.1 - 0.0018 18.4 0.1 0.0043 17.2 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE domain rve PF00665.21 OAI97396.1 - 1.5e-15 57.3 0.0 4.6e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain IPPT PF01715.12 OAI97398.1 - 9.1e-32 110.0 0.1 2.3e-27 95.6 0.1 3.2 2 1 0 2 2 2 2 IPP transferase SMI1_KNR4 PF09346.5 OAI97403.1 - 4.1e-23 81.8 0.0 6.7e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) PV-1 PF06637.6 OAI97406.1 - 0.015 13.9 1.8 0.016 13.8 1.2 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Phage_Mu_Gam PF07352.7 OAI97406.1 - 0.06 12.8 2.3 0.91 9.0 1.7 1.9 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DivIVA PF05103.8 OAI97406.1 - 0.072 13.1 5.2 0.1 12.6 3.6 1.2 1 0 0 1 1 1 0 DivIVA protein CENP-F_leu_zip PF10473.4 OAI97406.1 - 0.11 12.4 6.8 0.22 11.3 4.7 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC155 PF14662.1 OAI97406.1 - 0.31 10.6 8.0 0.61 9.6 5.6 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 DUF743 PF05332.6 OAI97406.1 - 0.34 10.8 2.0 0.51 10.3 1.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF743) APG6 PF04111.7 OAI97406.1 - 1 8.3 6.1 1.3 8.0 4.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 OAI97406.1 - 3.2 7.3 7.8 7.4 6.1 5.4 1.6 1 1 0 1 1 1 0 IncA protein Sua5_yciO_yrdC PF01300.13 OAI97412.1 - 1.9e-47 160.8 0.0 7e-46 155.7 0.0 2.5 1 1 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 OAI97412.1 - 3e-24 85.4 0.0 9.6e-23 80.6 0.0 2.5 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding AA_permease_2 PF13520.1 OAI97414.1 - 6.8e-55 186.3 50.5 8.4e-55 186.0 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAI97414.1 - 7.1e-12 44.4 50.1 1.6e-11 43.2 34.7 1.5 1 1 0 1 1 1 1 Amino acid permease Aldedh PF00171.17 OAI97416.1 - 3.3e-154 513.6 0.4 3.8e-154 513.4 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DEAD PF00270.24 OAI97426.1 - 3.3e-13 49.4 0.0 4.9e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase CoatB PF10389.4 OAI97427.1 - 0.045 13.6 0.6 0.063 13.1 0.4 1.2 1 0 0 1 1 1 0 Bacteriophage coat protein B Pkinase PF00069.20 OAI97430.1 - 4.3e-33 114.5 0.0 7e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI97430.1 - 2.4e-11 43.2 0.0 3.7e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Dimer_Tnp_hAT PF05699.9 OAI97432.1 - 9.8e-23 79.5 0.0 2.6e-22 78.2 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAI97432.1 - 0.003 17.4 0.0 0.009 15.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) DUF1178 PF06676.6 OAI97442.1 - 0.39 10.8 4.5 0.18 12.0 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) HsbA PF12296.3 OAI97450.1 - 4.9e-13 49.0 14.0 7.2e-13 48.4 9.7 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF1307 PF06998.6 OAI97450.1 - 0.015 15.3 0.3 0.023 14.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1307) DivIVA PF05103.8 OAI97450.1 - 0.052 13.6 1.0 0.082 12.9 0.7 1.2 1 0 0 1 1 1 0 DivIVA protein ATP-synt_G PF04718.10 OAI97453.1 - 3.1e-17 63.0 2.2 7.3e-17 61.9 0.1 2.2 1 1 1 2 2 2 1 Mitochondrial ATP synthase g subunit ApoC-I PF04691.7 OAI97453.1 - 0.027 14.1 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) SR-25 PF10500.4 OAI97453.1 - 0.06 12.8 8.5 0.078 12.4 5.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein KdpC PF02669.10 OAI97453.1 - 3 7.5 9.7 4 7.0 6.7 1.2 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Peptidase_S64 PF08192.6 OAI97453.1 - 3.9 5.6 6.5 4.6 5.4 4.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF2413 PF10310.4 OAI97453.1 - 7 5.3 13.5 4.7 5.9 8.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2413) Utp12 PF04003.7 OAI97454.1 - 7.2e-20 70.9 0.2 1e-19 70.4 0.2 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 OAI97454.1 - 5.3e-09 35.6 0.6 1.2e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat API5 PF05918.6 OAI97458.1 - 0.024 13.1 0.3 0.026 13.0 0.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Utp11 PF03998.8 OAI97458.1 - 0.024 14.4 0.1 0.026 14.3 0.1 1.1 1 0 0 1 1 1 0 Utp11 protein Adeno_PV PF03910.8 OAI97459.1 - 0.0048 16.0 0.1 0.0051 15.9 0.1 1.0 1 0 0 1 1 1 1 Adenovirus minor core protein PV DUF3619 PF12279.3 OAI97459.1 - 0.088 12.8 0.2 0.097 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) MGC-24 PF05283.6 OAI97459.1 - 0.85 9.3 7.2 0.94 9.2 5.0 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Spt5-NGN PF03439.8 OAI97464.1 - 4.5e-17 61.5 0.0 1.1e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 OAI97464.1 - 5.7e-10 39.6 12.0 5.7e-10 39.6 8.3 3.7 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 OAI97464.1 - 0.00034 20.2 9.9 0.0049 16.5 0.1 3.2 3 0 0 3 3 3 2 KOW motif Chordopox_G2 PF05796.7 OAI97464.1 - 0.083 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus protein G2 Ribosomal_L19 PF01245.15 OAI97464.1 - 0.6 9.9 3.7 10 5.9 1.1 2.6 1 1 1 2 2 2 0 Ribosomal protein L19 Peptidase_M43 PF05572.8 OAI97471.1 - 1.9e-19 69.7 0.1 2.9e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.1 OAI97471.1 - 5.2e-05 22.8 0.2 9e-05 22.0 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 OAI97471.1 - 0.00018 22.0 0.9 0.00057 20.4 0.6 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 OAI97471.1 - 0.00047 20.2 0.9 0.00083 19.4 0.4 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAI97471.1 - 0.00088 19.2 0.6 0.0014 18.5 0.4 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 OAI97471.1 - 0.0031 17.2 0.1 0.0047 16.6 0.0 1.2 1 0 0 1 1 1 1 Matrixin Peptidase_M7 PF02031.11 OAI97471.1 - 0.0093 15.6 0.6 0.025 14.3 0.4 1.7 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family gag-asp_proteas PF13975.1 OAI97474.1 - 0.0031 17.3 0.0 0.0074 16.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAI97474.1 - 0.0035 17.8 0.0 0.0072 16.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 OAI97474.1 - 0.0041 17.1 1.7 0.0097 15.9 1.2 1.6 1 1 0 1 1 1 1 Retrotransposon gag protein RVT_2 PF07727.9 OAI97482.1 - 1e-72 244.1 0.0 1.3e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 OAI97482.1 - 0.017 14.9 0.1 0.24 11.1 0.0 2.6 2 0 0 2 2 2 0 Reverse transcriptase-like Autotransporter PF03797.14 OAI97482.1 - 0.046 13.0 0.1 0.075 12.3 0.1 1.2 1 0 0 1 1 1 0 Autotransporter beta-domain Pyridox_ox_2 PF12900.2 OAI97492.1 - 1.4e-36 125.4 0.0 1.9e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Helicase_C PF00271.26 OAI97493.1 - 2.2e-23 81.8 0.1 3.3e-23 81.3 0.1 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain tRNA-synt_1b PF00579.20 OAI97493.1 - 0.028 13.5 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) DUF4401 PF14351.1 OAI97496.1 - 3 6.7 12.1 0.045 12.7 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) PAAR_motif PF05488.8 OAI97499.1 - 0.00026 20.9 0.7 0.00065 19.6 0.4 1.7 1 1 0 1 1 1 1 PAAR motif OmdA PF13376.1 OAI97501.1 - 0.17 11.5 0.6 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated TPR_14 PF13428.1 OAI97507.1 - 0.024 15.2 2.2 0.7 10.7 0.1 3.9 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAI97507.1 - 0.1 12.5 0.4 16 5.6 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Fer2 PF00111.22 OAI97513.1 - 0.0074 16.0 2.9 0.012 15.3 2.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FYVE PF01363.16 OAI97513.1 - 0.025 14.4 2.4 0.037 13.9 1.6 1.3 1 0 0 1 1 1 0 FYVE zinc finger IBR PF01485.16 OAI97513.1 - 0.25 11.2 5.6 0.59 10.0 3.9 1.6 1 0 0 1 1 1 0 IBR domain DDE_Tnp_4 PF13359.1 OAI97523.1 - 1.4e-07 31.2 0.0 1.9e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Pyocin_S PF06958.7 OAI97528.1 - 1.4 9.2 6.1 4.2 7.7 0.4 2.1 2 0 0 2 2 2 0 S-type Pyocin FG-GAP_2 PF14312.1 OAI97534.1 - 0.13 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 FG-GAP repeat DUF3435 PF11917.3 OAI97535.1 - 0.13 10.9 1.8 0.17 10.5 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3435) zf-CCHC PF00098.18 OAI97540.1 - 0.0042 16.9 5.4 0.0083 16.0 3.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAI97540.1 - 0.021 14.5 0.7 0.047 13.4 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF4319 PF14203.1 OAI97540.1 - 0.042 13.3 0.1 0.086 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) DUF3136 PF11334.3 OAI97551.1 - 0.034 13.5 0.0 0.1 12.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) Mpp10 PF04006.7 OAI97570.1 - 6.5e-08 31.4 14.2 6.5e-08 31.4 9.8 3.9 2 1 2 4 4 4 1 Mpp10 protein Rox3 PF08633.5 OAI97572.1 - 4.2 7.6 19.7 0.41 10.9 3.2 3.0 3 0 0 3 3 3 0 Rox3 mediator complex subunit DNA_pol_viral_C PF00336.13 OAI97587.1 - 0.09 12.0 0.1 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain RVT_3 PF13456.1 OAI97587.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like DUF3840 PF12944.2 OAI97592.1 - 0.13 12.1 3.8 0.29 10.9 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3840) Tox-GHH PF15636.1 OAI97592.1 - 0.13 11.8 0.1 0.13 11.8 0.0 2.9 3 0 0 3 3 3 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF607 PF04678.8 OAI97592.1 - 2.8 7.8 4.8 4.8 7.0 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF607 NAM-associated PF14303.1 OAI97592.1 - 3 8.1 22.3 1.6 9.0 13.6 1.8 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain RAP1 PF07218.6 OAI97592.1 - 9.9 4.1 8.3 12 3.7 5.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DDE_Tnp_4 PF13359.1 OAI97593.1 - 1.3e-19 70.3 0.0 3.5e-19 68.9 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Enkurin PF13864.1 OAI97593.1 - 0.26 11.5 5.7 0.48 10.6 3.9 1.4 1 0 0 1 1 1 0 Calmodulin-binding RVT_3 PF13456.1 OAI97595.1 - 0.04 13.7 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like DNA_pol_viral_C PF00336.13 OAI97595.1 - 0.069 12.3 0.1 0.15 11.3 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain TniQ PF06527.6 OAI97601.1 - 0.24 11.5 2.3 0.53 10.4 1.6 1.5 1 0 0 1 1 1 0 TniQ KdpC PF02669.10 OAI97601.1 - 2.4 7.8 5.2 4.4 6.9 3.6 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain MitoNEET_N PF10660.4 OAI97602.1 - 0.05 13.4 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus RVT_1 PF00078.22 OAI97609.1 - 3.2e-15 56.0 0.0 5e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spc97_Spc98 PF04130.8 OAI97609.1 - 0.015 13.6 0.2 0.023 13.0 0.1 1.2 1 0 0 1 1 1 0 Spc97 / Spc98 family adh_short PF00106.20 OAI97612.1 - 2.1e-23 83.0 0.6 3.4e-23 82.4 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAI97612.1 - 5.4e-13 49.2 0.2 7e-13 48.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAI97612.1 - 1.4e-05 24.8 0.2 4.3e-05 23.2 0.1 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAI97612.1 - 1.9e-05 24.1 0.5 5.2e-05 22.7 0.1 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAI97612.1 - 0.00035 20.6 0.5 0.00066 19.7 0.3 1.5 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 OAI97612.1 - 0.0099 15.6 0.2 1.3 8.8 0.0 2.9 3 0 0 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ima1_N PF09779.4 OAI97621.1 - 6.2 7.3 6.7 6.3 7.3 0.2 2.8 2 0 0 2 2 2 0 Ima1 N-terminal domain MSA-2c PF12238.3 OAI97624.1 - 0.16 11.6 5.8 0.28 10.8 3.9 1.5 1 1 0 1 1 1 0 Merozoite surface antigen 2c DUF755 PF05501.6 OAI97625.1 - 3.7 7.6 29.0 6.8 6.7 20.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TMP-TENI PF02581.12 OAI97629.1 - 0.085 11.9 0.0 0.087 11.9 0.0 1.1 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI DPM2 PF07297.7 OAI97638.1 - 3.7e-24 84.7 0.2 4.5e-24 84.5 0.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 OAI97638.1 - 8.5e-06 25.4 0.1 9.7e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 PIG-P Sensor PF13796.1 OAI97638.1 - 0.017 14.7 1.6 0.018 14.6 1.1 1.1 1 0 0 1 1 1 0 Putative sensor DUF1206 PF06724.6 OAI97638.1 - 0.25 11.1 3.9 0.99 9.2 0.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) DUF1469 PF07332.6 OAI97638.1 - 0.74 9.5 4.1 3.4 7.4 2.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) DJ-1_PfpI PF01965.19 OAI97639.1 - 1.8e-26 92.3 0.1 2.8e-26 91.7 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 OAI97639.1 - 2.6e-12 46.3 0.0 3.4e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase VWA_2 PF13519.1 OAI97639.1 - 0.027 14.5 0.0 0.11 12.5 0.0 1.9 1 1 1 2 2 2 0 von Willebrand factor type A domain Peptidase_M16 PF00675.15 OAI97658.1 - 3.4e-23 82.0 0.0 4.2e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 OAI97658.1 - 1.1e-07 31.7 0.1 8.1e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Transaldolase PF00923.14 OAI97658.1 - 0.016 14.3 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Transaldolase TetR PF13972.1 OAI97659.1 - 0.00046 19.6 0.0 0.00052 19.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial transcriptional repressor HlyD_3 PF13437.1 OAI97660.1 - 9.4e-16 58.0 0.1 3.1e-12 46.7 0.0 3.2 3 1 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 OAI97660.1 - 1.7e-12 46.8 2.1 2.5e-05 23.8 0.1 3.3 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD_2 PF12700.2 OAI97660.1 - 3.8e-06 26.2 0.0 0.0023 17.1 0.0 2.1 1 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl PF00364.17 OAI97660.1 - 6.9e-06 25.6 0.0 0.028 14.0 0.0 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD PF00529.15 OAI97660.1 - 0.036 13.3 32.5 0.4 9.9 0.0 2.8 1 1 1 2 2 2 0 HlyD family secretion protein Peptidase_M23 PF01551.17 OAI97660.1 - 0.052 13.6 0.0 3.7 7.6 0.0 2.6 2 0 0 2 2 2 0 Peptidase family M23 DUF4610 PF15384.1 OAI97660.1 - 0.072 12.6 0.7 0.14 11.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4610) Lyase_aromatic PF00221.14 OAI97663.1 - 5.3e-07 28.4 2.8 0.0017 16.9 0.8 3.0 2 1 1 3 3 3 3 Aromatic amino acid lyase YL1 PF05764.8 OAI97668.1 - 0.11 12.1 13.6 0.15 11.6 9.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein TFIIF_alpha PF05793.7 OAI97668.1 - 0.21 9.8 20.3 0.29 9.4 14.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNase_H2-Ydr279 PF09468.5 OAI97668.1 - 1.7 7.7 13.0 0.37 9.9 4.6 2.0 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Exo_endo_phos PF03372.18 OAI97671.1 - 4.2e-18 66.1 0.0 6e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 OAI97671.1 - 0.0055 16.3 0.0 0.048 13.2 0.0 2.2 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Adeno_VII PF03228.9 OAI97671.1 - 0.24 11.9 0.0 0.24 11.9 0.0 2.8 2 1 1 3 3 3 0 Adenoviral core protein VII RVT_1 PF00078.22 OAI97676.1 - 2.2e-07 30.4 0.0 4.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAI97677.1 - 0.0061 17.0 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Herpes_ORF11 PF04797.8 OAI97677.1 - 0.017 13.6 0.0 0.025 13.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus dUTPase protein gag-asp_proteas PF13975.1 OAI97677.1 - 0.048 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAI97677.1 - 0.059 13.2 0.0 0.16 11.9 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease DUF1768 PF08719.6 OAI97684.1 - 8.2e-19 67.8 0.1 9.2e-19 67.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Membr_traf_MHD PF10540.4 OAI97696.1 - 3.2e-15 56.1 0.0 9.7e-15 54.5 0.0 1.8 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 OAI97696.1 - 0.00034 20.3 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain Glyco_hydro_cc PF11790.3 OAI97702.1 - 3.7e-53 180.4 0.9 4.2e-53 180.2 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core SurE PF01975.12 OAI97711.1 - 4.5e-40 137.0 0.0 7.5e-40 136.3 0.0 1.4 1 0 0 1 1 1 1 Survival protein SurE Transthyretin PF00576.16 OAI97716.1 - 4.7e-31 106.9 0.0 4.8e-30 103.7 0.0 1.9 1 1 0 1 1 1 1 HIUase/Transthyretin family COG5 PF10392.4 OAI97717.1 - 2.7e-10 40.2 2.4 3.4e-10 39.9 1.0 1.7 2 0 0 2 2 2 1 Golgi transport complex subunit 5 OmpW PF03922.9 OAI97722.1 - 0.057 13.0 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 OmpW family DUF2348 PF09807.4 OAI97728.1 - 0.00022 20.4 0.0 0.0004 19.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) NACHT PF05729.7 OAI97728.1 - 0.006 16.2 0.1 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Helicase_C PF00271.26 OAI97742.1 - 2.7e-08 33.5 0.0 4.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Peripla_BP_4 PF13407.1 OAI97742.1 - 0.034 13.4 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain 7TMR-HDED PF07697.6 OAI97748.1 - 0.045 13.4 0.1 0.061 13.0 0.1 1.2 1 0 0 1 1 1 0 7TM-HD extracellular DUF2937 PF11157.3 OAI97748.1 - 0.096 12.0 0.2 0.18 11.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) RVT_1 PF00078.22 OAI97750.1 - 2.4e-17 62.9 0.0 4.5e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GMC_oxred_N PF00732.14 OAI97754.1 - 3.5e-49 167.5 0.0 4.6e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAI97754.1 - 7.5e-07 28.3 0.9 0.00059 18.8 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAI97754.1 - 3.1e-05 23.0 0.2 0.0011 17.8 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 OAI97754.1 - 6.7e-05 23.0 0.2 0.11 12.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAI97754.1 - 7.1e-05 22.7 0.0 0.00021 21.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAI97754.1 - 0.0021 17.0 0.1 0.003 16.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 OAI97754.1 - 0.17 10.9 0.1 0.28 10.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Herpes_gE PF02480.11 OAI97759.1 - 0.22 9.7 0.1 0.34 9.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Sec61_beta PF03911.11 OAI97762.1 - 8.1e-17 60.7 0.3 1e-16 60.3 0.2 1.1 1 0 0 1 1 1 1 Sec61beta family NDUFB10 PF10249.4 OAI97764.1 - 0.0094 16.0 0.4 0.011 15.9 0.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HAD_2 PF13419.1 OAI97764.1 - 0.012 15.8 0.1 0.013 15.6 0.1 1.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF2890 PF11081.3 OAI97768.1 - 0.051 13.6 16.6 0.07 13.1 7.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) SOBP PF15279.1 OAI97768.1 - 0.085 13.2 7.3 0.12 12.6 5.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Nucleoplasmin PF03066.10 OAI97768.1 - 0.23 10.9 12.4 0.36 10.3 6.1 2.2 2 0 0 2 2 2 0 Nucleoplasmin Sigma70_ner PF04546.8 OAI97768.1 - 0.49 9.9 13.2 0.057 13.0 4.3 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region eIF3_subunit PF08597.5 OAI97768.1 - 0.91 9.0 11.8 0.2 11.1 3.3 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit YL1 PF05764.8 OAI97768.1 - 1.3 8.5 17.6 0.064 12.8 5.6 2.1 1 1 1 2 2 2 0 YL1 nuclear protein Med3 PF11593.3 OAI97768.1 - 1.3 8.1 21.5 2 7.5 14.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PRP21_like_P PF12230.3 OAI97768.1 - 2.5 7.5 11.4 0.16 11.4 2.5 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein RXT2_N PF08595.6 OAI97768.1 - 2.7 7.7 8.3 15 5.3 2.5 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Plasmodium_Vir PF05795.6 OAI97768.1 - 3.6 6.6 4.4 5.4 6.1 3.0 1.3 1 1 0 1 1 1 0 Plasmodium vivax Vir protein RAP1 PF07218.6 OAI97768.1 - 3.8 5.4 10.2 5.3 5.0 7.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PBP1_TM PF14812.1 OAI97768.1 - 8.3 6.7 24.2 0.075 13.3 5.3 2.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CM_2 PF01817.16 OAI97769.1 - 5.3e-07 29.6 0.0 0.00011 22.1 0.0 3.0 2 1 0 2 2 2 2 Chorismate mutase type II PMT PF02366.13 OAI97772.1 - 1.3e-12 47.6 3.3 1.7e-12 47.2 2.3 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Pkinase PF00069.20 OAI97776.1 - 6.3e-42 143.5 0.0 1.5e-41 142.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI97776.1 - 8.4e-23 80.7 0.0 2.3e-22 79.2 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Tropomyosin PF00261.15 OAI97776.1 - 0.00014 21.0 13.6 0.00014 21.0 9.4 4.1 1 1 3 4 4 4 2 Tropomyosin Tropomyosin_1 PF12718.2 OAI97776.1 - 0.0084 15.9 21.0 0.0084 15.9 14.6 4.1 1 1 2 4 4 4 2 Tropomyosin like AAA_27 PF13514.1 OAI97776.1 - 0.014 13.0 52.2 0.023 12.4 36.2 1.2 1 0 0 1 1 1 0 AAA domain APH PF01636.18 OAI97776.1 - 0.29 10.8 0.1 0.29 10.8 0.0 3.6 2 2 0 3 3 3 0 Phosphotransferase enzyme family DUF3504 PF12012.3 OAI97776.1 - 0.93 9.2 9.0 0.033 13.9 1.4 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3504) ERM PF00769.14 OAI97776.1 - 3.6 7.0 59.0 0.025 14.1 19.7 2.6 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 OAI97776.1 - 3.9 6.5 18.7 0.061 12.4 1.1 3.0 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Mo25 PF08569.6 OAI97781.1 - 1.4e-116 389.2 1.0 1.8e-109 365.8 2.6 2.6 1 1 1 2 2 2 2 Mo25-like HEAT_2 PF13646.1 OAI97781.1 - 0.024 14.9 0.0 0.56 10.5 0.0 2.8 3 0 0 3 3 3 0 HEAT repeats RepA_N PF06970.6 OAI97781.1 - 0.47 10.2 3.6 0.19 11.5 0.6 1.8 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus Sporozoite_P67 PF05642.6 OAI97781.1 - 9.4 3.9 18.9 16 3.2 13.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tbf5 PF06331.7 OAI97784.1 - 3.7e-23 81.0 0.1 4e-23 80.9 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 FlbD PF06289.6 OAI97784.1 - 0.072 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Flagellar protein (FlbD) F-box-like PF12937.2 OAI97788.1 - 4.1e-12 45.6 0.1 4.1e-12 45.6 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAI97788.1 - 3.2e-08 33.0 0.3 9.8e-08 31.4 0.0 1.9 2 0 0 2 2 2 1 F-box domain PQQ_2 PF13360.1 OAI97788.1 - 0.00081 18.9 0.1 0.0062 16.0 0.0 2.2 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 OAI97788.1 - 0.0036 16.7 1.6 0.016 14.7 0.1 2.6 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.1 OAI97788.1 - 0.0059 16.8 0.1 1.9 8.8 0.0 3.6 3 0 0 3 3 3 1 PQQ-like domain Arylsulfotran_2 PF14269.1 OAI97788.1 - 0.2 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) Abhydrolase_6 PF12697.2 OAI97794.1 - 2.1e-05 24.5 0.6 8.4e-05 22.5 0.1 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S8 PF00082.17 OAI97797.1 - 7.1e-45 153.3 0.0 1.9e-44 151.9 0.0 1.7 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 OAI97797.1 - 1.4e-10 41.5 0.0 3e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 OAI97797.1 - 2.1e-09 36.9 0.0 5e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF883 PF05957.8 OAI97800.1 - 0.16 12.3 0.3 0.25 11.7 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ABC_tran PF00005.22 OAI97805.1 - 1.3e-16 61.1 0.0 6.3e-16 58.9 0.0 2.0 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 OAI97805.1 - 1.6e-10 41.4 0.1 0.00012 22.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 OAI97805.1 - 9.7e-07 28.1 0.0 0.0049 15.9 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 OAI97805.1 - 0.0002 20.8 0.0 0.00042 19.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 OAI97805.1 - 0.0023 17.3 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 OAI97805.1 - 0.0028 16.9 0.1 1 8.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 OAI97805.1 - 0.0074 16.2 0.1 0.037 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 OAI97805.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.1 OAI97805.1 - 0.017 15.0 1.1 0.017 15.0 0.1 1.7 2 1 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 OAI97805.1 - 0.025 14.5 0.0 0.043 13.7 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.16 OAI97805.1 - 0.034 13.3 0.1 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_10 PF12846.2 OAI97805.1 - 0.041 13.3 0.7 0.18 11.2 0.1 2.0 1 1 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 OAI97805.1 - 0.045 14.0 0.0 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 OAI97805.1 - 0.05 12.7 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 OAI97805.1 - 0.059 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 OAI97805.1 - 0.071 13.6 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein MutS_V PF00488.16 OAI97805.1 - 0.075 12.4 0.1 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 MutS domain V Sigma54_activat PF00158.21 OAI97805.1 - 0.1 12.0 0.2 10 5.5 0.1 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 OAI97805.1 - 0.14 12.3 0.2 1.5 9.0 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 OAI97805.1 - 0.25 12.1 1.2 0.43 11.4 0.3 2.0 2 1 0 2 2 1 0 AAA domain Pantoate_transf PF02548.10 OAI97808.1 - 3.9e-87 291.6 0.5 3.9e-82 275.2 0.1 2.3 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 OAI97808.1 - 0.014 14.6 0.1 0.014 14.6 0.0 2.5 3 0 0 3 3 3 0 Phosphoenolpyruvate phosphomutase RNase_H PF00075.19 OAI97812.1 - 1.4e-14 54.5 0.0 3.1e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAI97812.1 - 0.00019 21.1 0.0 0.0006 19.5 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase-like RVT_1 PF00078.22 OAI97812.1 - 0.0024 17.2 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EIF_2_alpha PF07541.7 OAI97816.1 - 1.6e-38 130.8 0.0 3.2e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 OAI97816.1 - 1.8e-12 47.1 0.1 4.2e-12 45.9 0.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 OAI97816.1 - 0.044 13.7 0.1 0.097 12.6 0.1 1.6 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 AP_endonuc_2 PF01261.19 OAI97816.1 - 0.055 12.7 0.0 0.096 11.9 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Histone PF00125.19 OAI97817.1 - 8.5e-31 105.9 0.4 1e-30 105.6 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAI97817.1 - 1.4e-05 25.1 0.0 1.8e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAI97817.1 - 0.012 15.6 0.1 0.017 15.1 0.0 1.1 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 OAI97817.1 - 0.033 13.4 0.1 0.038 13.2 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 OAI97817.1 - 0.035 13.8 0.0 0.051 13.3 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated DDE_1 PF03184.14 OAI97827.1 - 1e-30 106.5 0.0 1.5e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAI97827.1 - 6.7e-10 38.6 0.0 3.4e-09 36.3 0.0 2.2 1 1 1 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 OAI97827.1 - 0.032 13.7 0.2 0.086 12.4 0.0 1.8 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Ribonuclease_3 PF00636.21 OAI97830.1 - 3.8e-15 56.3 2.9 5.6e-15 55.7 0.0 2.7 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 OAI97830.1 - 0.00013 21.9 0.0 0.017 15.0 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease-III-like Serglycin PF04360.7 OAI97830.1 - 5.5 6.7 8.0 0.42 10.3 1.8 1.8 2 0 0 2 2 2 0 Serglycin FHA PF00498.21 OAI97842.1 - 0.029 14.4 0.0 0.069 13.2 0.0 1.6 1 0 0 1 1 1 0 FHA domain DUF1543 PF07566.7 OAI97842.1 - 0.21 11.1 0.4 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1543) Helicase_C PF00271.26 OAI97848.1 - 1.8e-10 40.5 0.0 4.4e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Herpes_capsid PF06112.6 OAI97851.1 - 6.1 6.8 7.5 8.8 6.3 5.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein CBFB_NFYA PF02045.10 OAI97852.1 - 1.4e-18 67.1 26.6 3.1e-12 46.8 1.0 3.6 3 1 0 3 3 3 2 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Abhydrolase_6 PF12697.2 OAI97861.1 - 0.00049 20.0 0.0 0.0018 18.1 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAI97861.1 - 0.0042 16.8 0.0 0.012 15.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAI97861.1 - 0.04 13.5 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Tropomyosin_1 PF12718.2 OAI97879.1 - 0.11 12.2 5.5 0.14 11.9 3.8 1.1 1 0 0 1 1 1 0 Tropomyosin like DUF1423 PF07227.6 OAI97879.1 - 0.14 10.7 5.4 0.16 10.6 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) FixO PF02433.10 OAI97879.1 - 0.37 10.1 2.2 0.43 9.8 1.6 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO BLOC1_2 PF10046.4 OAI97879.1 - 0.38 10.9 2.5 0.98 9.5 0.9 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.4 OAI97879.1 - 1.1 8.0 3.9 1.3 7.8 2.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OmpH PF03938.9 OAI97879.1 - 1.5 8.7 10.8 1.9 8.4 7.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HlyD PF00529.15 OAI97879.1 - 9.5 5.4 15.9 11 5.2 11.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein LMWPc PF01451.16 OAI97886.1 - 6.6e-35 120.4 0.0 7.5e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Sgf11 PF08209.6 OAI97887.1 - 5.8e-13 47.9 3.1 6.9e-13 47.6 0.4 2.2 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 OAI97887.1 - 0.4 10.4 1.6 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Oligomerisation PF02410.10 OAI97891.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Oligomerisation domain V-ATPase_G PF03179.10 OAI97897.1 - 5.1e-33 113.5 18.3 6e-33 113.2 12.7 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 OAI97897.1 - 0.0042 16.8 21.6 0.0075 16.0 8.0 2.1 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) DUF3402 PF11882.3 OAI97897.1 - 0.053 12.5 7.2 0.054 12.5 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) ATP-synt_F6 PF05511.6 OAI97897.1 - 0.19 11.6 6.3 2.3 8.2 4.1 2.2 1 1 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Phage_Nu1 PF07471.7 OAI97897.1 - 0.33 10.4 5.6 0.38 10.2 3.9 1.2 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 DUF2317 PF10079.4 OAI97897.1 - 1 7.9 13.4 1.2 7.6 9.3 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) HrpE PF06188.7 OAI97897.1 - 1.1 9.0 9.4 1.3 8.6 6.5 1.2 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF1104 PF06518.6 OAI97897.1 - 1.1 9.4 11.9 2.3 8.4 8.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1104) Prominin PF05478.6 OAI97897.1 - 1.1 6.7 4.9 1.1 6.7 3.4 1.0 1 0 0 1 1 1 0 Prominin 4HB_MCP_1 PF12729.2 OAI97897.1 - 1.3 8.3 11.3 1.9 7.7 7.8 1.3 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction PTPlike_phytase PF14566.1 OAI97897.1 - 1.3 9.0 5.3 2 8.4 3.6 1.4 1 1 0 1 1 1 0 Inositol hexakisphosphate Seryl_tRNA_N PF02403.17 OAI97897.1 - 1.6 8.7 14.5 4.8 7.2 9.7 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Ribosomal_L28e PF01778.12 OAI97897.1 - 1.6 9.1 7.7 44 4.4 5.4 2.1 1 1 0 1 1 1 0 Ribosomal L28e protein family ATP11 PF06644.6 OAI97897.1 - 1.8 8.0 11.5 2 7.8 7.9 1.1 1 0 0 1 1 1 0 ATP11 protein DUF964 PF06133.6 OAI97897.1 - 1.8 8.6 12.6 1.5 8.8 6.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF964) DUF4375 PF14300.1 OAI97897.1 - 2.3 8.2 6.8 10 6.1 1.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) DUF3552 PF12072.3 OAI97897.1 - 3.3 6.8 21.0 18 4.5 14.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Vfa1 PF08432.5 OAI97897.1 - 3.5 7.6 15.1 4 7.4 10.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HAUS6_N PF14661.1 OAI97897.1 - 3.7 6.8 11.4 4.6 6.5 7.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4407 PF14362.1 OAI97897.1 - 3.7 6.4 13.3 4.9 6.0 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.8 OAI97897.1 - 3.9 6.4 6.5 4.6 6.2 4.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein AIF-MLS PF14962.1 OAI97897.1 - 3.9 7.0 9.2 3.2 7.3 5.8 1.4 1 1 0 1 1 1 0 Mitochondria Localisation Sequence DUF3450 PF11932.3 OAI97897.1 - 3.9 6.6 10.6 4.2 6.5 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) AAA_32 PF13654.1 OAI97897.1 - 4.3 5.8 12.2 4.4 5.8 8.5 1.0 1 0 0 1 1 1 0 AAA domain PA26 PF04636.8 OAI97897.1 - 5.7 5.5 7.8 6.1 5.4 5.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) eIF3_N PF09440.5 OAI97897.1 - 5.9 7.0 9.9 14 5.8 6.9 1.7 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain OmpH PF03938.9 OAI97897.1 - 6.2 6.7 17.4 8.9 6.2 12.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Mnd1 PF03962.10 OAI97897.1 - 6.3 6.4 13.4 7.7 6.1 9.3 1.2 1 0 0 1 1 1 0 Mnd1 family PEP-utilisers_N PF05524.8 OAI97897.1 - 6.4 6.5 9.6 15 5.3 1.8 2.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF2205 PF10224.4 OAI97899.1 - 2.6e-15 55.7 0.0 3.5e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 OAI97899.1 - 0.00095 19.4 0.0 0.0011 19.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Cast PF10174.4 OAI97899.1 - 0.08 10.9 0.0 0.09 10.8 0.0 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone RVT_1 PF00078.22 OAI97903.1 - 5.3e-13 48.8 0.0 1e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NAD_binding_10 PF13460.1 OAI97919.1 - 4.1e-11 43.2 0.0 5.5e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 OAI97919.1 - 7.9e-10 38.8 3.1 5.6e-08 32.8 1.0 3.0 2 1 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 OAI97919.1 - 5.3e-07 29.3 0.0 8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 OAI97919.1 - 0.0073 15.4 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Spt20 PF12090.3 OAI97920.1 - 2.4 7.4 8.4 3.2 7.0 1.7 2.2 2 0 0 2 2 2 0 Spt20 family FimP PF09766.4 OAI97920.1 - 3.7 6.5 14.1 4.3 6.3 0.5 2.3 2 0 0 2 2 2 0 Fms-interacting protein OmpH PF03938.9 OAI97920.1 - 5.9 6.7 13.5 3.6 7.5 0.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Actin PF00022.14 OAI97923.1 - 3.7e-76 256.0 0.0 4.5e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Actin MULE PF10551.4 OAI97931.1 - 5e-18 65.0 0.0 1.4e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.10 OAI97931.1 - 2.5e-12 46.1 0.1 6.2e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.13 OAI97931.1 - 6.9e-07 28.1 0.1 1.3e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 Transposase, Mutator family Ion_trans_N PF08412.5 OAI97931.1 - 0.049 12.9 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Ion transport protein N-terminal WH1 PF00568.18 OAI97931.1 - 0.084 12.5 0.2 0.23 11.1 0.1 1.7 2 0 0 2 2 2 0 WH1 domain Tim17 PF02466.14 OAI97936.1 - 3.9e-14 52.8 13.1 5.4e-14 52.3 9.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Mito_carr PF00153.22 OAI97937.1 - 3.7e-65 215.6 4.8 7e-24 83.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Nuc_N PF14448.1 OAI97945.1 - 0.017 14.6 0.0 0.55 9.8 0.0 2.5 2 0 0 2 2 2 0 Nuclease N terminal Asp_protease_2 PF13650.1 OAI97946.1 - 0.00072 19.9 0.2 0.0025 18.2 0.0 2.1 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI97946.1 - 0.022 14.5 0.3 0.094 12.5 0.1 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAI97946.1 - 0.049 13.5 0.1 0.38 10.6 0.0 2.3 2 1 0 2 2 2 0 Retroviral aspartyl protease Histone PF00125.19 OAI97949.1 - 9.9e-11 41.6 0.7 1.4e-10 41.0 0.1 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 BON PF04972.12 OAI97949.1 - 0.019 14.6 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 BON domain GspH PF12019.3 OAI97951.1 - 0.035 14.2 0.1 4.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Type II transport protein GspH BBP1_C PF15272.1 OAI97959.1 - 0.011 15.2 0.2 0.013 15.0 0.1 1.1 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Mto2_bdg PF12808.2 OAI97959.1 - 0.015 15.3 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF1944 PF09175.5 OAI97959.1 - 0.04 13.5 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1944) Sec2p PF06428.6 OAI97959.1 - 0.063 13.1 0.4 0.078 12.8 0.3 1.1 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p CRT10 PF08728.5 OAI97964.1 - 5.2 4.9 19.9 8.5 4.2 13.8 1.3 1 0 0 1 1 1 0 CRT10 PLRV_ORF5 PF01690.12 OAI97964.1 - 7.2 5.6 41.7 9.3 5.2 28.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Glyco_hydro_88 PF07470.8 OAI97971.1 - 6.1e-15 55.0 2.9 2.5e-14 53.0 0.1 2.3 3 0 0 3 3 3 2 Glycosyl Hydrolase Family 88 Biotin_lipoyl_2 PF13533.1 OAI97975.1 - 8e-11 41.4 2.1 1.3e-10 40.7 1.2 1.5 1 1 0 1 1 1 1 Biotin-lipoyl like HlyD PF00529.15 OAI97975.1 - 3.7e-07 29.7 2.0 4.4e-07 29.5 1.4 1.1 1 0 0 1 1 1 1 HlyD family secretion protein HlyD_2 PF12700.2 OAI97975.1 - 1.4e-06 27.7 0.0 1.6e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 HlyD family secretion protein Biotin_lipoyl PF00364.17 OAI97975.1 - 0.0071 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme PTS_EIIA_1 PF00358.15 OAI97975.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.3 1 1 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Abhydrolase_5 PF12695.2 OAI97976.1 - 3.6e-08 33.2 0.0 6.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAI97976.1 - 6.1e-07 29.5 0.0 1.6e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAI97976.1 - 2.5e-05 23.9 0.0 5.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.11 OAI97976.1 - 0.00011 21.7 0.0 0.075 12.4 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DUF676 PF05057.9 OAI97976.1 - 0.0016 17.8 0.1 0.0062 15.8 0.0 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) UPF0227 PF05728.7 OAI97976.1 - 0.0053 16.4 0.1 0.044 13.4 0.0 2.2 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.20 OAI97976.1 - 0.0063 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 OAI97976.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 OAI97976.1 - 0.13 11.6 0.0 0.44 9.9 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Chlorophyllase2 PF12740.2 OAI97976.1 - 0.19 10.5 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme LPAM_1 PF08139.7 OAI97976.1 - 1.7 9.0 6.4 4 7.8 4.4 1.7 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site TetR_N PF00440.18 OAI97977.1 - 3.8e-10 39.2 0.1 7.7e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family DDE_Tnp_4 PF13359.1 OAI97979.1 - 3.7e-23 81.8 0.0 4.5e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 OAI97979.1 - 1.4e-05 24.7 0.0 1.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain ACC_epsilon PF13822.1 OAI97980.1 - 0.25 11.7 7.0 0.71 10.2 4.9 1.9 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit DUF3829 PF12889.2 OAI97980.1 - 3.4 6.7 10.2 0.53 9.4 3.9 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3829) Pheromone PF08015.6 OAI97980.1 - 8.7 7.2 6.9 11 6.8 1.2 2.4 2 0 0 2 2 2 0 Fungal mating-type pheromone Pkinase PF00069.20 OAI97986.1 - 5.5e-21 74.8 0.0 8.7e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI97986.1 - 4.2e-11 42.4 0.0 6.2e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI97986.1 - 7.9e-09 34.8 0.0 1.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 OAI97986.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 OAI97986.1 - 0.067 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LIP PF03583.9 OAI97999.1 - 3.1e-22 79.1 0.0 3.6e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.16 OAI97999.1 - 0.00042 19.5 0.0 0.00052 19.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 OAI97999.1 - 0.0048 16.8 0.0 0.0052 16.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAI97999.1 - 0.0074 16.0 0.0 0.0084 15.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAI97999.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Cys_Met_Meta_PP PF01053.15 OAI98003.1 - 2e-132 441.1 0.0 3.8e-132 440.2 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 OAI98003.1 - 1.5e-05 23.5 0.0 2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.14 OAI98003.1 - 0.00012 20.9 0.0 0.00018 20.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 OAI98003.1 - 0.0098 14.8 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 OAI98003.1 - 0.014 14.0 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 Allinase zf-CCHC PF00098.18 OAI98008.1 - 0.0016 18.2 2.5 0.0028 17.4 1.7 1.4 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 OAI98008.1 - 0.012 16.1 0.0 0.03 14.8 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.1 OAI98008.1 - 0.019 14.4 0.6 0.038 13.5 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.1 OAI98008.1 - 0.029 14.1 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-DHHC PF01529.15 OAI98012.1 - 7.9 5.8 10.4 0.87 8.9 1.7 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF4064 PF13273.1 OAI98012.1 - 8.9 6.4 16.5 6.1 7.0 2.9 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) RVT_1 PF00078.22 OAI98015.1 - 2.4e-25 89.1 0.0 1.4e-24 86.6 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAI98015.1 - 0.12 11.9 0.7 3.3 7.3 0.5 3.0 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase BAAT_C PF08840.6 OAI98015.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Septin PF00735.13 OAI98018.1 - 0.013 14.5 0.0 0.015 14.3 0.0 1.0 1 0 0 1 1 1 0 Septin zf-CCHC PF00098.18 OAI98024.1 - 0.0016 18.2 2.5 0.0029 17.4 1.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAI98024.1 - 0.019 14.4 0.6 0.039 13.4 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.1 OAI98024.1 - 0.024 14.4 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAI98024.1 - 0.03 14.8 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Sugar-bind PF04198.8 OAI98033.1 - 0.2 10.5 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 Putative sugar-binding domain rve PF00665.21 OAI98038.1 - 0.001 19.1 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain LTD PF00932.14 OAI98038.1 - 0.022 14.7 0.1 0.045 13.8 0.1 1.5 1 0 0 1 1 1 0 Lamin Tail Domain rve_3 PF13683.1 OAI98038.1 - 0.093 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Ldh_1_C PF02866.13 OAI98043.1 - 5.6e-07 29.4 0.0 8.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ECH PF00378.15 OAI98050.1 - 6.1e-19 68.1 0.0 8.4e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ExbD PF02472.11 OAI98059.1 - 0.15 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR rve PF00665.21 OAI98060.1 - 1.9e-17 63.5 0.0 2.9e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 OAI98060.1 - 0.00089 18.8 0.1 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA PF00004.24 OAI98065.1 - 8.9e-34 116.5 0.0 1.4e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAI98065.1 - 3.8e-06 27.0 0.2 0.12 12.5 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 OAI98065.1 - 3.8e-05 23.3 0.2 0.0046 16.6 0.0 3.0 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 OAI98065.1 - 3.9e-05 23.7 0.5 0.00017 21.6 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 OAI98065.1 - 4.5e-05 23.1 0.0 0.00018 21.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 OAI98065.1 - 0.00053 19.4 1.5 0.046 13.1 0.3 2.4 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 OAI98065.1 - 0.0012 19.6 0.1 0.0063 17.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAI98065.1 - 0.0029 17.4 0.1 0.0071 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 OAI98065.1 - 0.0049 16.7 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 OAI98065.1 - 0.0081 15.7 0.1 0.56 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 OAI98065.1 - 0.0099 15.4 0.0 0.017 14.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAI98065.1 - 0.037 14.3 1.7 0.26 11.6 0.0 2.5 2 2 0 2 2 2 0 AAA domain AAA_28 PF13521.1 OAI98065.1 - 0.041 13.8 0.1 0.18 11.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 OAI98065.1 - 0.093 12.3 0.0 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 OAI98065.1 - 0.18 11.5 0.6 0.82 9.3 0.0 2.2 2 1 0 2 2 2 0 Archaeal ATPase ANF_receptor PF01094.23 OAI98065.1 - 0.24 10.1 0.5 12 4.5 0.1 2.1 1 1 1 2 2 2 0 Receptor family ligand binding region Asp PF00026.18 OAI98069.1 - 6.1e-53 180.1 7.0 1.1e-52 179.2 4.9 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAI98069.1 - 1.9e-06 27.8 2.3 2.3e-05 24.3 1.6 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 OAI98069.1 - 0.0049 16.4 0.2 0.01 15.4 0.1 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Transposase_21 PF02992.9 OAI98075.1 - 7.4e-13 48.1 0.0 2.1e-12 46.6 0.0 1.7 1 1 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 OAI98075.1 - 4.1e-05 23.0 0.0 7.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) zf-C2HC5 PF06221.8 OAI98075.1 - 0.058 13.1 0.1 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-UDP PF14569.1 OAI98075.1 - 0.23 11.2 1.2 0.56 10.0 0.8 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger DNA_ligase_ZBD PF03119.11 OAI98075.1 - 5.6 6.7 7.0 0.5 10.1 0.3 2.2 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Fringe PF02434.11 OAI98088.1 - 2.2e-05 23.8 0.7 0.00021 20.6 0.3 2.3 2 1 0 2 2 2 1 Fringe-like 60KD_IMP PF02096.15 OAI98095.1 - 2.2e-39 135.1 0.5 3.6e-39 134.4 0.4 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein DUF1152 PF06626.7 OAI98095.1 - 0.0056 15.8 0.0 0.009 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1152) Pap_E4 PF02711.9 OAI98095.1 - 1.5 9.6 6.9 6.1 7.7 4.8 2.0 1 0 0 1 1 1 0 E4 protein PP_M1 PF03012.9 OAI98095.1 - 2.9 7.1 4.8 4.5 6.5 3.3 1.2 1 0 0 1 1 1 0 Phosphoprotein RMMBL PF07521.7 OAI98102.1 - 0.067 13.0 0.6 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase Steroid_dh PF02544.11 OAI98115.1 - 1.4e-32 112.5 0.5 2.4e-32 111.8 0.3 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 OAI98115.1 - 2.1e-07 30.5 0.1 3.5e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ubiquitin PF00240.18 OAI98115.1 - 1.1e-05 24.7 0.0 1.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family ICMT PF04140.9 OAI98115.1 - 0.0011 19.1 0.2 0.0025 17.9 0.1 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family COX6A PF02046.10 OAI98115.1 - 0.0013 18.5 0.1 0.0024 17.7 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa PEMT PF04191.8 OAI98115.1 - 0.0027 17.7 2.4 0.0097 16.0 0.5 2.3 1 1 2 3 3 3 1 Phospholipid methyltransferase DUF2986 PF11661.3 OAI98116.1 - 0.0039 17.4 0.7 0.0039 17.4 0.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) DUF1768 PF08719.6 OAI98121.1 - 5.4e-26 91.2 0.0 7.6e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Asp_protease_2 PF13650.1 OAI98126.1 - 4.6e-05 23.8 0.1 8.3e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI98126.1 - 0.00044 20.0 0.1 0.00084 19.1 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAI98126.1 - 0.0015 18.3 0.0 0.0029 17.5 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Synaptobrevin PF00957.16 OAI98131.1 - 1e-26 92.3 0.2 1.4e-26 91.8 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 OAI98131.1 - 2.3e-19 68.7 0.0 3.3e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain Iso_dh PF00180.15 OAI98132.1 - 5e-91 305.2 0.0 1.2e-90 303.9 0.0 1.5 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase FBPase_glpX PF03320.8 OAI98137.1 - 0.0013 17.4 1.5 0.0016 17.1 1.0 1.1 1 0 0 1 1 1 1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded RD3 PF14473.1 OAI98137.1 - 0.29 10.6 1.7 0.55 9.7 1.2 1.4 1 0 0 1 1 1 0 RD3 protein HMG_box PF00505.14 OAI98152.1 - 1.8e-20 72.9 0.8 1.8e-20 72.9 0.5 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 OAI98152.1 - 1.3e-13 51.0 1.1 1.3e-13 51.0 0.7 1.9 1 1 1 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 OAI98152.1 - 0.49 10.2 9.5 0.2 11.4 4.3 2.0 1 1 0 1 1 1 0 HMG (high mobility group) box 5 DUF2384 PF09722.5 OAI98159.1 - 2.1e-05 24.2 0.0 3.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2384) MFS_1 PF07690.11 OAI98163.1 - 2e-17 62.9 45.4 2e-17 62.9 31.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAI98163.1 - 2.8e-05 22.5 21.1 7.5e-05 21.1 14.6 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) rve PF00665.21 OAI98169.1 - 6.1e-22 77.9 0.0 1.4e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain UBN2 PF14223.1 OAI98169.1 - 3.2e-08 33.3 0.0 5.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAI98169.1 - 3.3e-07 29.8 0.0 5.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAI98169.1 - 0.0092 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_2 PF07727.9 OAI98169.1 - 0.011 14.7 0.1 0.015 14.2 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) GntR PF00392.16 OAI98169.1 - 0.027 13.8 0.2 1.1 8.7 0.1 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family RVP PF00077.15 OAI98169.1 - 0.034 14.0 0.1 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.18 OAI98169.1 - 3.8 7.6 11.5 0.51 10.3 5.1 1.8 2 0 0 2 2 2 0 Zinc knuckle Thi4 PF01946.12 OAI98175.1 - 3.1e-44 150.7 0.0 4.1e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 OAI98175.1 - 3e-08 32.9 0.9 7.5e-06 25.0 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.19 OAI98175.1 - 5.8e-07 28.7 0.0 7.1e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAI98175.1 - 3.2e-06 27.0 0.0 6.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAI98175.1 - 0.00016 21.5 0.1 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAI98175.1 - 0.00051 19.8 0.0 0.0012 18.6 0.0 1.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 OAI98175.1 - 0.0046 15.8 0.3 0.0099 14.7 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 OAI98175.1 - 0.03 12.7 0.1 0.04 12.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.11 OAI98175.1 - 0.049 13.0 0.2 0.58 9.5 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 OAI98175.1 - 0.065 11.8 0.0 0.079 11.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DUF3304 PF11745.3 OAI98175.1 - 0.12 12.5 0.1 0.21 11.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3304) RHD3 PF05879.7 OAI98176.1 - 0.0035 15.3 0.0 0.0035 15.3 0.0 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Cactin_mid PF10312.4 OAI98179.1 - 1.6e-60 203.6 4.3 1.6e-60 203.6 3.0 1.9 2 0 0 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.4 OAI98179.1 - 4.1e-54 181.4 6.1 7.6e-54 180.6 4.2 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Polysacc_deac_1 PF01522.16 OAI98184.1 - 3.9e-27 94.3 0.0 7.7e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Sporozoite_P67 PF05642.6 OAI98184.1 - 0.16 9.7 13.6 0.59 7.9 9.4 1.7 1 1 0 1 1 1 0 Sporozoite P67 surface antigen WEMBL PF05701.6 OAI98188.1 - 0.00066 18.2 20.5 0.054 11.9 4.2 2.5 2 1 0 2 2 2 2 Weak chloroplast movement under blue light APG6 PF04111.7 OAI98188.1 - 0.0033 16.5 0.8 0.0033 16.5 0.5 3.2 2 2 1 3 3 3 1 Autophagy protein Apg6 Cast PF10174.4 OAI98188.1 - 0.039 12.0 26.8 0.016 13.2 6.0 2.6 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone Filament PF00038.16 OAI98188.1 - 0.1 12.0 20.7 0.32 10.4 3.5 3.8 2 2 2 4 4 4 0 Intermediate filament protein RVT_1 PF00078.22 OAI98198.1 - 3.4e-11 42.9 0.0 6.7e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 OAI98198.1 - 0.14 12.0 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAI98198.1 - 0.18 12.3 0.0 1.1 9.7 0.0 2.3 3 0 0 3 3 3 0 Aspartyl protease RVT_2 PF07727.9 OAI98201.1 - 1.7e-85 285.9 0.0 2.2e-85 285.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAI98201.1 - 0.039 13.2 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Zeta_toxin PF06414.7 OAI98206.1 - 0.025 13.7 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Pkinase PF00069.20 OAI98211.1 - 8.3e-26 90.6 0.1 2.8e-25 88.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI98211.1 - 4.5e-15 55.4 0.1 1.3e-14 53.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase HisK_N PF09385.5 OAI98211.1 - 0.1 12.2 0.3 0.25 10.9 0.2 1.6 1 0 0 1 1 1 0 Histidine kinase N terminal KKLCAg1 PF15204.1 OAI98217.1 - 0.06 13.3 0.1 0.065 13.2 0.0 1.1 1 0 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 MMR_HSR1 PF01926.18 OAI98219.1 - 3.8e-12 46.1 0.0 2.5e-11 43.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAI98219.1 - 0.0009 18.5 0.1 0.0018 17.5 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 OAI98219.1 - 0.0013 18.5 0.1 0.0053 16.5 0.1 2.1 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 OAI98219.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SspB PF04386.8 OAI98219.1 - 1.2 8.6 3.6 0.63 9.6 0.2 2.1 2 0 0 2 2 2 0 Stringent starvation protein B Bax1-I PF01027.15 OAI98224.1 - 3.1e-44 151.0 20.9 3.7e-44 150.7 14.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF3464 PF11947.3 OAI98224.1 - 1.4 8.3 6.2 2 7.8 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3464) Pox_I5 PF04713.7 OAI98224.1 - 5 6.9 8.7 1.1 8.9 0.1 2.9 2 1 1 3 3 3 0 Poxvirus protein I5 Nop53 PF07767.6 OAI98225.1 - 1.4e-21 76.9 0.5 9.7e-21 74.1 0.4 1.9 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Phage_integrase PF00589.17 OAI98233.1 - 0.00026 20.7 0.1 0.00035 20.2 0.1 1.3 1 0 0 1 1 1 1 Phage integrase family zf-BED PF02892.10 OAI98255.1 - 0.001 18.7 0.4 0.001 18.7 0.3 2.0 2 0 0 2 2 2 1 BED zinc finger zf-C2H2 PF00096.21 OAI98255.1 - 0.073 13.4 0.7 0.22 11.9 0.5 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type PRCC PF10253.4 OAI98255.1 - 1.2 9.8 6.6 1.3 9.6 3.0 2.1 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Med3 PF11593.3 OAI98255.1 - 5.8 6.0 11.1 10 5.2 7.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1509 PF07420.6 OAI98260.1 - 0.16 11.2 4.5 0.18 11.0 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) eIF3_subunit PF08597.5 OAI98268.1 - 0.015 14.8 9.9 0.021 14.3 6.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1227 PF06777.6 OAI98268.1 - 0.086 12.5 0.4 0.14 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1227) ATP11 PF06644.6 OAI98268.1 - 0.13 11.7 4.3 0.19 11.2 3.0 1.2 1 0 0 1 1 1 0 ATP11 protein Complex1_LYR PF05347.10 OAI98268.1 - 0.24 11.2 1.2 0.57 10.0 0.8 1.6 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DUF2457 PF10446.4 OAI98268.1 - 0.31 9.7 6.6 0.43 9.2 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Tom37_C PF11801.3 OAI98268.1 - 0.92 9.3 2.9 1.4 8.7 2.0 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF4192 PF13830.1 OAI98268.1 - 1.8 8.1 11.7 3 7.3 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) SPX PF03105.14 OAI98272.1 - 3.8e-29 102.3 4.4 3.1e-27 96.0 3.1 3.1 1 1 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.20 OAI98272.1 - 1.8e-06 27.5 7.3 3.2e-06 26.6 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAI98272.1 - 2.7e-06 27.1 7.1 5.5e-06 26.1 4.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 OAI98272.1 - 5.6e-06 25.9 6.9 5.6e-06 25.9 4.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAI98272.1 - 6.1e-06 25.9 10.8 1.5e-05 24.7 7.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAI98272.1 - 7.3e-06 25.9 10.0 7.3e-06 25.9 6.9 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAI98272.1 - 0.00066 19.3 7.0 0.00066 19.3 4.8 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAI98272.1 - 0.002 17.8 5.4 0.0047 16.6 3.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 OAI98272.1 - 0.012 15.1 2.2 0.025 14.1 1.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 OAI98272.1 - 0.032 13.7 4.8 0.095 12.2 3.3 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 OAI98272.1 - 0.98 9.5 7.0 3.1 7.9 4.9 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger zf-P11 PF03854.9 OAI98272.1 - 1.5 8.3 6.2 2.8 7.4 4.3 1.4 1 0 0 1 1 1 0 P-11 zinc finger Transferase PF02458.10 OAI98278.1 - 6.5e-09 34.7 0.0 0.00089 17.8 0.0 3.1 3 0 0 3 3 3 3 Transferase family DUF4218 PF13960.1 OAI98284.1 - 1.3e-06 27.9 0.0 2.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF2235 PF09994.4 OAI98290.1 - 2e-28 99.5 0.0 2.3e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 OAI98290.1 - 0.042 13.6 0.1 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2235 PF09994.4 OAI98291.1 - 8.4e-23 81.1 0.1 1.2e-22 80.5 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Mso1_C PF14477.1 OAI98291.1 - 0.053 13.8 0.3 0.13 12.5 0.2 1.6 1 0 0 1 1 1 0 Membrane-polarising domain of Mso1 WD40 PF00400.27 OAI98299.1 - 2.9e-23 80.8 5.4 1.4e-07 31.0 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat IKI3 PF04762.7 OAI98299.1 - 0.00034 18.5 0.9 0.045 11.5 0.3 2.2 2 0 0 2 2 2 2 IKI3 family eIF2A PF08662.6 OAI98299.1 - 0.0031 17.2 0.4 0.11 12.2 0.3 2.9 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF837 PF05769.6 OAI98309.1 - 1.4e-05 24.7 7.8 0.00018 21.1 2.2 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF837) Nop14 PF04147.7 OAI98309.1 - 0.0017 16.3 29.1 0.003 15.5 20.2 1.4 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 OAI98309.1 - 0.25 9.7 33.2 0.66 8.4 23.0 1.7 1 0 0 1 1 1 0 Daxx Family RRM_1 PF00076.17 OAI98318.1 - 4.1e-09 35.9 0.0 9.6e-09 34.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAI98318.1 - 6.8e-08 32.3 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) LEA_4 PF02987.11 OAI98318.1 - 0.00067 19.4 4.8 0.00067 19.4 3.4 2.8 2 1 1 3 3 3 1 Late embryogenesis abundant protein RRM_5 PF13893.1 OAI98318.1 - 0.0051 16.6 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF883 PF05957.8 OAI98318.1 - 0.014 15.7 2.0 0.014 15.7 1.4 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1798 PF08807.5 OAI98318.1 - 0.24 11.1 2.9 0.19 11.4 0.5 1.9 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) YtxH PF12732.2 OAI98318.1 - 2.3 8.6 15.9 21 5.5 6.6 3.7 2 1 0 2 2 2 0 YtxH-like protein PGAP1 PF07819.8 OAI98322.1 - 0.0002 21.0 0.0 0.00042 19.9 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 OAI98322.1 - 0.0034 17.1 0.0 0.0074 16.0 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAI98322.1 - 0.018 14.9 0.2 0.04 13.8 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Phage_integrase PF00589.17 OAI98325.1 - 9.1e-05 22.1 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family GRP PF07172.6 OAI98342.1 - 1.7 9.2 14.6 3.2 8.2 10.1 1.4 1 1 0 1 1 1 0 Glycine rich protein family Serglycin PF04360.7 OAI98343.1 - 0.3 10.7 1.6 0.58 9.8 1.1 1.4 1 0 0 1 1 1 0 Serglycin RVT_1 PF00078.22 OAI98349.1 - 0.0088 15.4 0.0 0.022 14.1 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Zn_clus PF00172.13 OAI98359.1 - 2.9e-10 39.8 2.4 5.2e-10 39.0 1.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Menin PF05053.8 OAI98359.1 - 4.6 5.3 12.8 6.6 4.7 8.9 1.2 1 0 0 1 1 1 0 Menin Phage_integrase PF00589.17 OAI98367.1 - 0.00012 21.8 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DUF2945 PF11160.3 OAI98375.1 - 0.026 14.3 0.4 6.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2945) DUF1542 PF07564.6 OAI98375.1 - 0.055 13.4 2.2 3.3 7.7 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) DUF3460 PF11943.3 OAI98375.1 - 0.14 12.2 1.8 6.6 6.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) Lactamase_B PF00753.22 OAI98379.1 - 0.036 13.7 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Acyltransferase PF01553.16 OAI98380.1 - 1e-34 118.7 0.0 1.5e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Pex26 PF07163.7 OAI98381.1 - 0.07 12.0 0.5 0.1 11.4 0.3 1.3 1 0 0 1 1 1 0 Pex26 protein ATP-grasp PF02222.17 OAI98389.1 - 6.5e-53 178.6 0.0 2.1e-30 105.3 0.0 2.2 1 1 1 2 2 2 2 ATP-grasp domain AIRC PF00731.15 OAI98389.1 - 2e-15 56.3 0.0 5.1e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp_4 PF13535.1 OAI98389.1 - 5e-09 36.1 0.1 6.3e-08 32.5 0.1 2.3 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 OAI98389.1 - 3.7e-05 23.1 0.0 0.00013 21.3 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 OAI98389.1 - 0.00098 18.5 0.0 0.0032 16.8 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.14 OAI98389.1 - 0.0014 17.8 0.0 0.0029 16.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 OAI98389.1 - 0.012 15.2 0.1 0.034 13.7 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HTH_9 PF08221.6 OAI98390.1 - 2.3e-17 62.6 0.0 1.5e-07 31.1 0.0 3.3 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain NIT PF08376.5 OAI98399.1 - 0.036 13.6 0.2 0.081 12.4 0.2 1.5 1 0 0 1 1 1 0 Nitrate and nitrite sensing Exo_endo_phos PF03372.18 OAI98400.1 - 0.0012 18.8 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 OAI98400.1 - 0.0028 17.2 0.0 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF1528 PF07515.6 OAI98405.1 - 9.5e-43 144.5 0.0 1.2e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1528) Pantoate_ligase PF02569.10 OAI98406.1 - 6.5e-104 346.6 0.0 7.3e-104 346.4 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase OPT PF03169.10 OAI98413.1 - 1.8e-88 297.6 39.5 2e-88 297.4 27.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3353 PF11833.3 OAI98413.1 - 0.64 9.4 4.1 0.69 9.3 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) Methyltransf_2 PF00891.13 OAI98416.1 - 1.1e-29 103.3 0.0 1.8e-29 102.6 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 OAI98416.1 - 0.00025 21.4 0.0 0.00055 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAI98416.1 - 0.0049 16.4 0.0 0.0063 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAI98416.1 - 0.006 16.3 0.0 0.0082 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAI98416.1 - 0.0096 16.4 0.0 0.021 15.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Pkinase PF00069.20 OAI98420.1 - 1.2e-46 158.9 0.0 8.2e-44 149.7 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAI98420.1 - 2.2e-22 79.4 0.0 7e-22 77.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 OAI98420.1 - 0.0029 16.6 0.2 0.0047 16.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAI98420.1 - 0.054 12.4 0.0 0.19 10.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like RNA_pol_3_Rpc31 PF11705.3 OAI98439.1 - 1.1e-26 94.2 25.4 2.8e-26 92.9 17.6 1.8 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Vps16_N PF04841.8 OAI98440.1 - 1.2e-12 47.0 0.0 2.8e-12 45.8 0.0 1.5 2 0 0 2 2 2 1 Vps16, N-terminal region p450 PF00067.17 OAI98445.1 - 1.3e-40 139.3 0.0 1.4e-40 139.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 rve PF00665.21 OAI98453.1 - 1.8e-05 24.7 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAI98453.1 - 0.0068 15.8 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain PGG PF13962.1 OAI98460.1 - 0.14 11.8 3.3 0.17 11.5 0.0 2.6 3 1 0 3 3 3 0 Domain of unknown function DUF4064 PF13273.1 OAI98460.1 - 1.2 9.2 9.6 9.5 6.3 0.0 3.2 3 2 0 3 3 3 0 Protein of unknown function (DUF4064) Arif-1 PF06770.6 OAI98460.1 - 3.1 7.1 8.5 0.78 9.0 0.1 2.6 3 0 0 3 3 3 0 Actin-rearrangement-inducing factor (Arif-1) Orbi_NS3 PF01616.11 OAI98460.1 - 7.7 5.4 6.0 4.4 6.2 0.2 2.5 2 1 0 3 3 3 0 Orbivirus NS3 Phage_integrase PF00589.17 OAI98465.1 - 0.00053 19.7 0.0 0.00086 19.0 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 OAI98466.1 - 0.038 13.3 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Sec1 PF00995.18 OAI98474.1 - 0.013 14.1 0.1 0.016 13.8 0.0 1.1 1 0 0 1 1 1 0 Sec1 family Sec1 PF00995.18 OAI98475.1 - 0.0092 14.6 0.0 0.013 14.1 0.0 1.2 1 1 0 1 1 1 1 Sec1 family Sigma70_ner PF04546.8 OAI98483.1 - 0.0016 18.0 1.0 0.0016 18.0 0.7 2.6 2 1 0 2 2 2 1 Sigma-70, non-essential region SR-25 PF10500.4 OAI98489.1 - 0.036 13.5 6.2 0.049 13.0 4.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 OAI98489.1 - 0.29 10.4 1.8 0.43 9.9 1.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF508 PF04370.7 OAI98489.1 - 0.54 9.8 2.5 0.82 9.2 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) GTP_EFTU PF00009.22 OAI98496.1 - 3.2e-08 33.2 0.0 5.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF4407 PF14362.1 OAI98502.1 - 0.44 9.4 4.1 0.53 9.1 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L10 PF00466.15 OAI98503.1 - 1.5e-24 85.7 0.0 3.1e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 OAI98503.1 - 2.8e-24 85.3 10.6 2.8e-24 85.3 7.4 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein MULE PF10551.4 OAI98509.1 - 3.4e-15 55.9 0.1 6.6e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 OAI98509.1 - 9.2e-07 29.3 1.6 2.1e-06 28.1 1.1 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain Transposase_mut PF00872.13 OAI98509.1 - 8.6e-06 24.5 0.0 1.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_IS240 PF13610.1 OAI98509.1 - 0.0014 18.5 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 DDE domain AFT PF08731.6 OAI98509.1 - 0.11 12.7 2.0 0.15 12.2 0.5 1.9 2 1 0 2 2 2 0 Transcription factor AFT DUF1722 PF08349.6 OAI98509.1 - 0.11 12.4 0.3 0.22 11.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) gp12-short_mid PF09089.5 OAI98509.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Phage short tail fibre protein gp12, middle domain DUF3106 PF11304.3 OAI98522.1 - 0.32 11.4 4.0 0.43 11.0 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Sec1 PF00995.18 OAI98540.1 - 8.2e-09 34.6 0.1 1.1e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Nucleocapsid-N PF11030.3 OAI98540.1 - 0.15 11.8 1.4 0.26 11.1 1.0 1.3 1 0 0 1 1 1 0 Nucleocapsid protein N Myb_DNA-bind_3 PF12776.2 OAI98544.1 - 1e-14 54.9 0.5 1.8e-14 54.0 0.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAI98544.1 - 9.8e-06 25.6 1.8 8e-05 22.7 1.3 2.1 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain MFS_1 PF07690.11 OAI98553.1 - 2e-09 36.6 24.7 2e-09 36.6 17.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pardaxin PF07425.6 OAI98560.1 - 0.65 9.4 4.3 0.79 9.1 1.1 2.2 2 0 0 2 2 2 0 Pardaxin AAA_18 PF13238.1 OAI98565.1 - 2.2e-07 31.2 0.2 2e-06 28.1 0.2 2.3 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 OAI98565.1 - 1.4e-06 28.0 0.0 2.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 OAI98565.1 - 0.00054 20.7 0.3 0.003 18.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 OAI98565.1 - 0.022 14.4 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 OAI98565.1 - 0.034 14.1 1.0 0.22 11.4 0.7 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 OAI98565.1 - 0.058 13.2 0.3 0.15 11.9 0.2 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 OAI98565.1 - 0.11 11.5 0.1 0.19 10.7 0.1 1.5 1 1 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 OAI98565.1 - 0.12 12.3 0.5 0.27 11.1 0.4 1.6 1 0 0 1 1 1 0 AAA domain SH3_8 PF13457.1 OAI98572.1 - 0.052 13.7 0.1 0.086 13.0 0.1 1.4 1 0 0 1 1 1 0 SH3-like domain Lipase_chap PF03280.9 OAI98579.1 - 0.019 14.4 3.6 0.028 13.9 2.5 1.2 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein DUF148 PF02520.12 OAI98579.1 - 0.057 13.2 0.4 0.12 12.1 0.3 1.6 1 1 1 2 2 2 0 Domain of unknown function DUF148 RVT_1 PF00078.22 OAI98586.1 - 8.8e-16 57.8 0.0 1.8e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI98586.1 - 4.5e-13 49.3 0.0 8.1e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain MaoC_dehydrat_N PF13452.1 OAI98591.1 - 1.5e-09 37.7 0.0 2.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Acyl_transf_1 PF00698.16 OAI98592.1 - 1.8e-51 175.3 0.0 2.8e-47 161.6 0.0 2.2 1 1 1 2 2 2 2 Acyl transferase domain MaoC_dehydratas PF01575.14 OAI98592.1 - 3.3e-26 91.0 0.0 1.3e-25 89.1 0.0 1.9 2 0 0 2 2 2 1 MaoC like domain NifU_N PF01592.11 OAI98596.1 - 1.8e-52 176.6 0.1 2.9e-52 175.9 0.1 1.4 1 0 0 1 1 1 1 NifU-like N terminal domain NMO PF03060.10 OAI98597.1 - 5e-51 173.8 0.6 4e-50 170.8 0.4 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 OAI98597.1 - 5.2e-07 28.8 0.9 0.0079 15.1 0.5 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 OAI98597.1 - 0.00014 20.8 0.1 0.00023 20.1 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 OAI98597.1 - 0.026 13.8 0.1 0.053 12.7 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Glu_synthase PF01645.12 OAI98597.1 - 0.045 12.6 1.3 0.14 11.0 0.9 1.9 1 1 0 1 1 1 0 Conserved region in glutamate synthase DUF1902 PF08972.6 OAI98597.1 - 0.06 12.9 1.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) DHO_dh PF01180.16 OAI98597.1 - 0.12 11.3 0.2 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Abhydrolase_5 PF12695.2 OAI98604.1 - 0.039 13.6 0.0 0.093 12.4 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAI98604.1 - 0.051 13.4 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Nfu_N PF08712.6 OAI98620.1 - 2.9e-33 113.3 0.0 1.2e-32 111.3 0.0 2.0 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 OAI98620.1 - 2.6e-20 71.9 0.1 4.2e-20 71.2 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Med25_NR-box PF11244.3 OAI98620.1 - 0.085 13.3 15.1 0.16 12.4 10.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing Pex14_N PF04695.8 OAI98620.1 - 0.64 10.0 9.3 1.5 8.9 5.7 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Shisa PF13908.1 OAI98620.1 - 3.8 7.6 6.2 5.7 7.0 4.3 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Pyr_redox_2 PF07992.9 OAI98621.1 - 7.3e-29 101.0 0.2 8.9e-29 100.8 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAI98621.1 - 4.7e-18 65.3 0.1 3e-15 56.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAI98621.1 - 3.5e-08 33.7 0.1 0.00085 19.4 0.0 3.1 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAI98621.1 - 1.5e-06 27.4 0.1 9e-05 21.6 0.0 2.5 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 OAI98621.1 - 3.8e-06 26.2 0.0 0.038 13.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 OAI98621.1 - 2.2e-05 23.5 2.0 0.0053 15.6 0.1 3.5 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 OAI98621.1 - 4.1e-05 22.8 0.2 0.036 13.1 0.0 3.0 2 1 1 3 3 3 1 FAD binding domain DAO PF01266.19 OAI98621.1 - 0.0001 21.3 3.1 0.006 15.5 0.0 3.3 2 2 2 4 4 4 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 OAI98621.1 - 0.00013 22.1 0.2 0.0098 16.1 0.0 2.9 2 2 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 OAI98621.1 - 0.00014 21.7 0.4 0.0097 15.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 OAI98621.1 - 0.00018 21.6 0.0 0.14 12.3 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 OAI98621.1 - 0.0019 17.1 3.9 0.005 15.7 0.3 2.5 2 1 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 OAI98621.1 - 0.0037 15.9 0.1 0.053 12.1 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.9 OAI98621.1 - 0.0045 15.5 0.1 0.028 12.9 0.1 2.3 3 0 0 3 3 3 1 HI0933-like protein K_oxygenase PF13434.1 OAI98621.1 - 0.0045 15.9 0.0 0.57 9.0 0.0 3.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 OAI98621.1 - 0.024 14.2 0.2 0.095 12.2 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Homeobox PF00046.24 OAI98633.1 - 2.8e-23 81.2 1.4 1.5e-14 53.3 0.1 2.7 2 0 0 2 2 2 2 Homeobox domain Homeobox_KN PF05920.6 OAI98633.1 - 1.5e-05 24.5 0.7 0.002 17.8 0.1 2.6 2 0 0 2 2 2 1 Homeobox KN domain SusE PF14292.1 OAI98633.1 - 0.0085 15.9 0.2 3.2 7.5 0.1 2.5 2 1 0 2 2 2 2 SusE outer membrane protein HTH_28 PF13518.1 OAI98633.1 - 0.017 15.1 0.1 3.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain 2Fe-2S_thioredx PF01257.14 OAI98633.1 - 0.022 14.3 0.1 0.31 10.6 0.1 2.2 2 0 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin HTH_23 PF13384.1 OAI98633.1 - 0.05 13.2 0.1 19 5.0 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain zf-CCHC PF00098.18 OAI98639.1 - 2.3e-06 27.2 2.4 2.3e-06 27.2 1.6 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAI98639.1 - 0.027 13.9 0.3 0.046 13.2 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 OAI98639.1 - 0.046 13.2 1.7 0.099 12.1 1.2 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.1 OAI98639.1 - 0.068 12.8 0.7 0.12 12.1 0.5 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF1329 PF07044.6 OAI98646.1 - 1.5e-87 293.9 0.0 1.7e-87 293.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1329) MCPsignal PF00015.16 OAI98647.1 - 4.7e-46 157.0 30.4 3.9e-45 153.9 12.4 2.2 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_9 PF13426.1 OAI98647.1 - 1.3e-13 51.1 0.0 4.1e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 OAI98647.1 - 3.1e-11 43.2 0.0 7.5e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 OAI98647.1 - 1.3e-10 41.0 0.0 1.6e-09 37.5 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 OAI98647.1 - 1.1e-07 31.8 0.2 1e-06 28.7 0.0 2.7 2 1 1 3 3 3 1 PAS fold PAS_8 PF13188.1 OAI98647.1 - 0.011 15.5 0.0 0.038 13.8 0.0 1.9 1 0 0 1 1 1 0 PAS domain HAMP PF00672.20 OAI98647.1 - 0.018 15.2 11.9 4.3 7.6 3.3 4.1 2 2 0 2 2 2 0 HAMP domain Syntaxin PF00804.20 OAI98647.1 - 0.019 15.1 11.7 0.067 13.3 0.5 3.0 1 1 2 3 3 3 0 Syntaxin CRIC_ras_sig PF10534.4 OAI98647.1 - 0.051 13.6 0.9 0.14 12.2 0.6 1.8 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras Seryl_tRNA_N PF02403.17 OAI98647.1 - 0.51 10.3 4.1 2.6 8.1 0.0 3.2 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.7 OAI98647.1 - 1.8 8.3 14.7 0.22 11.2 2.0 3.1 2 1 1 3 3 3 0 Laminin Domain II 5-FTHF_cyc-lig PF01812.15 OAI98656.1 - 4.5e-28 98.2 0.0 8.4e-27 94.1 0.0 2.2 2 0 0 2 2 2 1 5-formyltetrahydrofolate cyclo-ligase family CBFD_NFYB_HMF PF00808.18 OAI98658.1 - 1.5e-14 53.7 0.0 1.7e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAI98658.1 - 3.2e-06 27.1 0.0 3.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 OAI98658.1 - 0.0045 16.7 0.1 0.0045 16.7 0.0 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region TRAM PF01938.15 OAI98658.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.4 1 1 0 1 1 1 0 TRAM domain CK_II_beta PF01214.13 OAI98662.1 - 3.9e-77 257.9 0.1 1.1e-76 256.4 0.0 1.8 2 0 0 2 2 2 1 Casein kinase II regulatory subunit CDC27 PF09507.5 OAI98662.1 - 0.6 9.2 17.5 1.3 8.1 12.1 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Band_3_cyto PF07565.8 OAI98662.1 - 0.75 9.2 5.5 1 8.8 3.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Suf PF05843.9 OAI98662.1 - 2 8.0 7.5 4.1 7.0 5.2 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4400 PF14348.1 OAI98692.1 - 5.9e-59 198.7 7.0 6.6e-59 198.6 4.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4400) GATA PF00320.22 OAI98699.1 - 2.9e-05 23.3 5.7 0.0001 21.5 2.9 2.3 1 1 1 2 2 2 1 GATA zinc finger ADK_lid PF05191.9 OAI98699.1 - 0.082 12.5 1.6 0.17 11.5 1.1 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid VGLL4 PF15245.1 OAI98705.1 - 0.11 12.3 1.7 0.16 11.7 1.1 1.2 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Pkr1 PF08636.5 OAI98714.1 - 1.6e-18 66.4 1.9 2e-18 66.2 1.3 1.1 1 0 0 1 1 1 1 ER protein Pkr1 TGS PF02824.16 OAI98715.1 - 3.4e-20 71.6 0.1 6.4e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 OAI98715.1 - 6.5e-19 67.9 0.0 1.3e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAI98715.1 - 2.4e-11 43.1 0.0 4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 OAI98715.1 - 0.0011 18.7 0.2 0.045 13.5 0.0 2.4 1 1 1 2 2 2 1 Dynamin family MCM PF00493.18 OAI98715.1 - 0.02 13.6 0.0 0.038 12.7 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family Miro PF08477.8 OAI98715.1 - 0.026 15.0 0.0 0.063 13.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein DUF1002 PF06207.6 OAI98715.1 - 0.069 12.4 0.7 0.12 11.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) AAA_16 PF13191.1 OAI98715.1 - 0.092 12.7 0.1 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain RVT_1 PF00078.22 OAI98727.1 - 1.7e-13 50.4 0.1 2.7e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF605 PF04652.11 OAI98750.1 - 1.8 7.8 24.7 2.6 7.3 17.1 1.2 1 0 0 1 1 1 0 Vta1 like Pex14_N PF04695.8 OAI98750.1 - 3.1 7.8 5.1 13 5.7 3.6 2.1 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pho88 PF10032.4 OAI98757.1 - 1.3e-60 203.9 0.0 1.4e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DEC-1_N PF04625.8 OAI98757.1 - 1.4 7.5 6.4 2 6.9 4.4 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Ribosomal_60s PF00428.14 OAI98757.1 - 2.3 8.6 9.8 3.4 8.1 6.8 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein CTK3 PF12243.3 OAI98758.1 - 2.2e-28 98.6 0.0 4.1e-28 97.7 0.0 1.4 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 OAI98758.1 - 5.9e-14 51.8 2.5 6.9e-11 42.0 0.1 2.5 2 0 0 2 2 2 2 CTD kinase subunit gamma CTK3 C-terminus rve PF00665.21 OAI98777.1 - 8.2e-16 58.2 0.0 2.1e-15 56.8 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAI98777.1 - 1.8e-09 37.2 0.1 4e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltransf_23 PF13489.1 OAI98792.1 - 1.1e-14 54.5 0.0 2.4e-14 53.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAI98792.1 - 1.3e-09 38.3 0.0 2.3e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAI98792.1 - 1.5e-08 35.0 0.0 2.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAI98792.1 - 8.4e-06 26.3 0.0 1.5e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAI98792.1 - 0.00016 21.2 0.0 0.00035 20.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 OAI98792.1 - 0.00024 19.9 0.0 0.00033 19.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 OAI98792.1 - 0.0027 17.2 0.0 0.004 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 OAI98792.1 - 0.015 15.3 0.0 0.052 13.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 OAI98792.1 - 0.065 12.5 0.0 0.12 11.7 0.0 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Cmc1 PF08583.5 OAI98807.1 - 3.7e-10 39.4 1.5 5.8e-10 38.8 1.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Barwin PF00967.12 OAI98807.1 - 0.093 12.4 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Barwin family SH3_1 PF00018.23 OAI98814.1 - 4.3e-11 42.0 0.0 7.2e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAI98814.1 - 4.2e-09 35.8 0.0 6.8e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAI98814.1 - 2.6e-07 30.0 0.0 3.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Polysacc_deac_1 PF01522.16 OAI98824.1 - 2.5e-23 82.0 0.0 5.1e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase OppC_N PF12911.2 OAI98825.1 - 0.08 12.3 0.0 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF1768 PF08719.6 OAI98835.1 - 1.8e-12 47.2 0.0 3.1e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) NAD_binding_8 PF13450.1 OAI98844.1 - 1.2e-13 50.8 0.0 2.9e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAI98844.1 - 0.00054 18.9 0.1 0.0071 15.2 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAI98844.1 - 0.043 12.8 0.1 0.069 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 OAI98844.1 - 0.079 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ras PF00071.17 OAI98851.1 - 5.1e-54 182.0 0.0 5.9e-54 181.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAI98851.1 - 1.1e-14 54.9 0.0 1.5e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAI98851.1 - 1.9e-07 30.4 0.0 3.4e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAI98851.1 - 0.0097 15.0 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 OAI98851.1 - 0.039 13.4 0.0 1.7 8.0 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sugar_tr PF00083.19 OAI98858.1 - 0.0035 15.9 6.1 0.0046 15.6 4.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter EF_assoc_1 PF08355.7 OAI98858.1 - 0.058 12.6 1.2 0.13 11.6 0.8 1.5 1 0 0 1 1 1 0 EF hand associated zf-CCHC PF00098.18 OAI98868.1 - 0.00088 19.0 0.2 0.0013 18.5 0.2 1.3 1 0 0 1 1 1 1 Zinc knuckle RVT_2 PF07727.9 OAI98869.1 - 1.1e-32 112.9 0.0 1.2e-31 109.5 0.0 2.0 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI98869.1 - 2.2e-23 82.6 0.0 3.7e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAI98869.1 - 1.6e-06 27.6 0.0 3.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAI98869.1 - 0.0032 16.9 0.0 0.0075 15.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain CRAL_TRIO PF00650.15 OAI98876.1 - 0.11 11.9 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 CRAL/TRIO domain DUF3742 PF12553.3 OAI98876.1 - 0.14 12.6 0.0 3.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) TPK_catalytic PF04263.11 OAI98877.1 - 5.1e-17 61.5 0.0 8.6e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 OAI98877.1 - 2.1e-09 36.9 0.0 3.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Med3 PF11593.3 OAI98886.1 - 4.9 6.2 10.3 5.9 6.0 7.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Herpes_capsid PF06112.6 OAI98886.1 - 5.3 7.0 8.7 8 6.4 6.1 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Asp_protease_2 PF13650.1 OAI98887.1 - 3.4e-05 24.2 0.0 8.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI98887.1 - 0.00022 21.0 0.0 0.00076 19.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAI98887.1 - 0.0065 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-C3HC4_3 PF13920.1 OAI98898.1 - 0.048 13.3 3.1 0.092 12.4 2.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MIP-T3 PF10243.4 OAI98899.1 - 0.81 8.0 5.9 0.89 7.9 4.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Tubulin PF00091.20 OAI98928.1 - 1.5e-63 214.5 0.0 3.1e-63 213.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 OAI98928.1 - 1.1e-40 138.6 0.0 1.6e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 OAI98928.1 - 0.00022 21.2 0.0 0.00074 19.5 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 OAI98928.1 - 0.002 17.6 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain ART PF01129.13 OAI98928.1 - 0.1 11.6 0.1 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase Tubulin_2 PF13809.1 OAI98928.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Tubulin like CPSase_L_D2 PF02786.12 OAI98936.1 - 4e-93 310.5 0.0 2.5e-82 275.2 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 OAI98936.1 - 1.2e-41 141.2 0.3 3e-41 140.0 0.1 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 OAI98936.1 - 9.7e-35 119.0 0.0 3e-16 59.5 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 OAI98936.1 - 1.9e-21 76.6 0.0 9.9e-16 57.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAI98936.1 - 2.2e-18 66.1 0.0 3e-07 29.4 0.0 3.2 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 OAI98936.1 - 5.1e-10 38.9 0.0 6.3e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 OAI98936.1 - 1.2e-08 34.6 0.0 0.00012 21.5 0.0 2.6 2 1 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 OAI98936.1 - 1.1e-05 25.0 0.0 0.064 12.7 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 OAI98936.1 - 1.5e-05 24.3 0.1 0.02 14.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 OAI98936.1 - 2.7e-05 24.0 0.0 9.5e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Aldo_ket_red PF00248.16 OAI98946.1 - 9.9e-46 155.8 0.0 3.3e-29 101.6 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family 6PGD PF00393.14 OAI98947.1 - 3.7e-131 436.6 0.0 4.3e-131 436.4 0.0 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain TPR_12 PF13424.1 OAI98962.1 - 8.4e-11 41.6 21.3 3.4e-05 23.6 1.1 4.6 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 OAI98962.1 - 2e-07 30.6 21.1 0.0047 16.8 0.4 6.2 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAI98962.1 - 0.00016 21.3 16.4 0.026 14.4 0.3 5.4 5 1 1 6 6 6 3 Tetratricopeptide repeat Apc5 PF12862.2 OAI98962.1 - 0.00098 18.9 8.9 0.27 11.0 0.5 4.2 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 5 TPR_1 PF00515.23 OAI98962.1 - 0.0018 17.8 5.8 0.15 11.7 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAI98962.1 - 0.0025 18.1 1.3 1.2 9.4 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAI98962.1 - 0.0036 16.9 0.6 1.4 8.8 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat MIT PF04212.13 OAI98962.1 - 0.0074 16.1 6.6 0.022 14.6 1.2 3.0 2 1 0 2 2 2 1 MIT (microtubule interacting and transport) domain MTBP_C PF14920.1 OAI98962.1 - 0.0087 15.5 1.7 0.011 15.2 0.5 1.5 1 1 1 2 2 2 1 MDM2-binding TPR_14 PF13428.1 OAI98962.1 - 0.0095 16.4 17.0 0.08 13.6 0.7 5.8 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAI98962.1 - 0.027 14.1 0.6 0.027 14.1 0.4 3.8 4 2 0 4 4 4 0 TPR repeat His_kinase PF06580.8 OAI98962.1 - 0.12 12.2 0.6 1.9 8.4 0.0 2.7 2 1 0 2 2 2 0 Histidine kinase TPR_7 PF13176.1 OAI98962.1 - 0.47 10.3 6.2 2.3 8.2 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Varsurf_PPLC PF03490.8 OAI98971.1 - 4.4e-05 23.0 0.0 0.00012 21.7 0.0 1.7 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C PI-PLC-X PF00388.14 OAI98971.1 - 8.3e-05 22.0 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain zf-RING_UBOX PF13445.1 OAI98979.1 - 0.00092 18.8 0.1 0.0018 17.9 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Phage_AlpA PF05930.7 OAI98979.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) SPRR2 PF14820.1 OAI98979.1 - 1 9.2 10.0 1 9.2 5.4 1.9 2 0 0 2 2 2 0 Small proline-rich 2 DUF2347 PF09804.4 OAI98989.1 - 5.8e-30 104.5 0.0 1.4e-29 103.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 OAI98989.1 - 0.0017 16.9 0.0 0.0025 16.3 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 Nucleoplasmin PF03066.10 OAI98989.1 - 0.043 13.3 9.0 0.5 9.8 1.3 2.3 2 0 0 2 2 2 0 Nucleoplasmin BSP_II PF05432.6 OAI98989.1 - 0.15 11.3 12.4 1.1 8.5 2.1 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Afi1 PF07792.7 OAI98989.1 - 0.34 10.8 0.0 0.34 10.8 0.0 2.6 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Myc_N PF01056.13 OAI98989.1 - 0.89 8.6 11.1 1 8.4 2.1 2.7 2 0 0 2 2 2 0 Myc amino-terminal region FHA PF00498.21 OAI99011.1 - 0.071 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 FHA domain DNA_pol_viral_C PF00336.13 OAI99024.1 - 0.083 12.1 0.2 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain BAF1_ABF1 PF04684.8 OAI99024.1 - 8.8 5.0 7.0 12 4.6 4.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Peptidase_S8 PF00082.17 OAI99034.1 - 3.7e-42 144.4 6.7 2.2e-41 141.8 4.6 2.1 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 OAI99034.1 - 2.3e-13 50.5 2.0 3.5e-13 49.9 0.0 2.4 2 1 0 2 2 2 1 Fn3-like domain (DUF1034) PA PF02225.17 OAI99034.1 - 0.0041 16.7 0.0 0.011 15.3 0.0 1.8 1 0 0 1 1 1 1 PA domain IDO PF01231.13 OAI99041.1 - 7e-121 403.5 0.0 1.4e-100 336.6 0.0 2.1 2 0 0 2 2 2 2 Indoleamine 2,3-dioxygenase HTH_Tnp_Tc5 PF03221.11 OAI99052.1 - 1.7e-07 30.9 0.0 4.3e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_4 PF13613.1 OAI99052.1 - 0.00018 20.9 0.0 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease MarR_2 PF12802.2 OAI99052.1 - 0.0027 17.3 0.0 0.0066 16.0 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_23 PF13384.1 OAI99052.1 - 0.0055 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain MarR PF01047.17 OAI99052.1 - 0.0057 16.3 0.4 0.017 14.8 0.0 2.0 2 0 0 2 2 2 1 MarR family CENP-B_N PF04218.8 OAI99052.1 - 0.0065 15.8 0.1 0.011 15.0 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 OAI99052.1 - 0.0091 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.1 OAI99052.1 - 0.026 14.2 0.0 0.026 14.2 0.0 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_28 PF13518.1 OAI99052.1 - 0.044 13.7 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 OAI99052.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF1566 PF07603.6 OAI99064.1 - 0.0027 17.4 0.6 0.0055 16.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1566) zf-BED PF02892.10 OAI99064.1 - 0.014 15.0 0.1 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 BED zinc finger RVT_3 PF13456.1 OAI99103.1 - 0.011 15.4 0.2 0.054 13.2 0.1 2.0 2 0 0 2 2 2 0 Reverse transcriptase-like DNA_pol_viral_C PF00336.13 OAI99103.1 - 0.045 13.0 0.1 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain Phage_integrase PF00589.17 OAI99104.1 - 0.0036 16.9 0.0 0.0039 16.8 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family LIP PF03583.9 OAI99115.1 - 1.5e-34 119.5 0.5 2e-34 119.1 0.3 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 OAI99115.1 - 0.0071 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAI99115.1 - 0.0074 16.0 0.1 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 OAI99115.1 - 0.025 14.2 0.1 0.041 13.6 0.1 1.3 1 0 0 1 1 1 0 Cutinase UPF0029 PF01205.14 OAI99133.1 - 1.2e-24 86.1 0.0 7.6e-24 83.5 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.17 OAI99133.1 - 0.0015 18.3 0.0 0.0044 16.8 0.0 1.7 1 1 0 1 1 1 1 RWD domain E1-E2_ATPase PF00122.15 OAI99155.1 - 1.1e-51 175.1 2.5 1.6e-51 174.5 1.7 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 OAI99155.1 - 8.8e-17 60.3 0.0 1.7e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.21 OAI99155.1 - 4.9e-16 59.7 0.0 1.2e-14 55.2 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAI99155.1 - 3.1e-14 52.6 0.0 5.9e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 OAI99155.1 - 6.6e-07 29.6 0.0 2.1e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.4 OAI99155.1 - 0.0059 16.2 1.6 0.2 11.2 0.0 2.6 2 1 0 2 2 2 1 Predicted membrane protein (DUF2157) PAZ PF02170.17 OAI99166.1 - 1.6e-11 43.6 0.0 2.2e-11 43.1 0.0 1.3 1 1 0 1 1 1 1 PAZ domain Aconitase_B_N PF11791.3 OAI99166.1 - 0.008 16.0 0.1 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Aconitate B N-terminal domain HTH_29 PF13551.1 OAI99166.1 - 0.03 14.4 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix DUF2106 PF09879.4 OAI99211.1 - 0.0052 16.1 0.3 0.0071 15.7 0.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2106) WD40 PF00400.27 OAI99225.1 - 1.2e-20 72.5 0.4 6.4e-11 41.7 0.1 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 OAI99225.1 - 0.0006 18.0 0.1 0.14 10.2 0.0 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Racemase_4 PF13615.1 OAI99226.1 - 2.7e-15 56.4 0.0 7.6e-15 55.0 0.0 1.8 1 1 0 1 1 1 1 Putative alanine racemase MCM_bind PF09739.4 OAI99226.1 - 4.3e-15 55.3 0.0 1.1e-13 50.8 0.0 2.3 1 1 0 1 1 1 1 Mini-chromosome maintenance replisome factor TAF8_C PF10406.4 OAI99249.1 - 0.062 13.3 1.0 0.4 10.7 0.1 2.2 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term LCCL PF03815.14 OAI99260.1 - 1.5e-16 60.1 0.0 2.7e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 LCCL domain DUF4579 PF15158.1 OAI99260.1 - 5.9 6.3 4.9 19 4.6 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4579) DUF4637 PF15470.1 OAI99270.1 - 0.2 11.2 6.9 0.045 13.3 2.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4637) Macoilin PF09726.4 OAI99270.1 - 0.86 7.8 7.3 0.96 7.6 5.1 1.0 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 OAI99270.1 - 8.8 6.1 11.3 11 5.8 7.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RVT_2 PF07727.9 OAI99271.1 - 1.6e-49 168.0 0.0 2.2e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBN2 PF14223.1 OAI99285.1 - 1.3e-05 24.9 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAI99285.1 - 0.078 12.9 11.4 0.064 13.2 5.8 2.3 2 0 0 2 2 2 0 Zinc knuckle UPF0552 PF10574.4 OAI99293.1 - 0.1 12.0 0.3 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0552 NOA36 PF06524.7 OAI99293.1 - 0.21 10.8 0.7 0.22 10.7 0.5 1.1 1 0 0 1 1 1 0 NOA36 protein CAP PF00188.21 OAI99309.1 - 2.6e-06 27.9 0.1 3.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RIO1 PF01163.17 OAI99310.1 - 9.2e-64 214.2 0.7 9.2e-64 214.2 0.5 2.4 2 1 0 2 2 2 1 RIO1 family SDA1 PF05285.7 OAI99310.1 - 0.58 9.3 30.1 0.22 10.7 11.6 2.4 2 0 0 2 2 2 0 SDA1 DUF1631 PF07793.6 OAI99322.1 - 0.19 9.8 1.0 0.23 9.5 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DDE_Tnp_4 PF13359.1 OAI99323.1 - 1.4e-15 57.2 0.0 1.9e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.1 OAI99323.1 - 0.0062 16.0 0.0 0.018 14.5 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DUF4611 PF15387.1 OAI99333.1 - 0.036 14.1 1.6 0.11 12.7 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PP_M1 PF03012.9 OAI99333.1 - 0.1 11.9 1.5 0.17 11.2 1.0 1.3 1 0 0 1 1 1 0 Phosphoprotein Hydrolase_6 PF13344.1 OAI99334.1 - 1.1e-17 63.8 0.0 1.6e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Dimer_Tnp_hAT PF05699.9 OAI99346.1 - 5.7e-16 57.9 0.0 1.1e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Endonuc-FokI_C PF09254.6 OAI99346.1 - 0.04 12.9 0.7 0.077 12.0 0.5 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Pkinase PF00069.20 OAI99347.1 - 3.2e-33 114.9 0.0 4.1e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI99347.1 - 2.3e-17 62.9 0.0 2.9e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI99347.1 - 4.3e-05 22.6 0.0 6.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAI99347.1 - 0.0004 19.5 0.0 0.0006 18.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 OAI99347.1 - 0.0074 15.1 0.3 0.0097 14.7 0.2 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 OAI99347.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 OAI99347.1 - 0.081 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family adh_short PF00106.20 OAI99368.1 - 6.3e-08 32.7 0.8 3.9e-07 30.1 0.3 2.2 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAI99368.1 - 0.00074 19.3 0.0 0.0013 18.5 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAI99368.1 - 0.004 17.1 0.0 0.0069 16.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 OAI99368.1 - 0.018 14.2 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.20 OAI99369.1 - 1.2e-09 38.3 1.6 3.4e-09 36.8 0.1 2.5 3 2 0 3 3 3 1 short chain dehydrogenase Epimerase PF01370.16 OAI99369.1 - 5.2e-07 29.3 0.0 7.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 OAI99369.1 - 1.8e-06 27.9 0.0 7.6e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAI99369.1 - 2.3e-06 27.7 0.0 8.2e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 OAI99369.1 - 0.01 15.5 0.0 0.087 12.6 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 OAI99369.1 - 0.031 13.9 0.1 3 7.4 0.1 2.9 1 1 1 2 2 2 0 KR domain HHH_5 PF14520.1 OAI99369.1 - 0.089 12.9 0.1 0.3 11.2 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain SRP_SPB PF02978.14 OAI99383.1 - 0.042 14.1 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal peptide binding domain Trns_repr_metal PF02583.12 OAI99383.1 - 0.072 13.2 1.3 0.095 12.9 0.3 1.7 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor Phage_int_SAM_1 PF02899.12 OAI99384.1 - 0.066 13.3 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain CTP_transf_2 PF01467.21 OAI99391.1 - 1.2e-07 31.9 0.0 2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 OAI99391.1 - 0.0074 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 FAD synthetase Mito_carr PF00153.22 OAI99392.1 - 3.1e-60 199.9 5.7 8.5e-24 83.0 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF1370 PF07114.6 OAI99392.1 - 0.0026 16.9 0.0 0.0054 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1370) Methyltransf_10 PF05971.7 OAI99400.1 - 9.8e-52 175.9 0.0 4.9e-31 107.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 OAI99400.1 - 0.003 17.5 0.0 0.0088 16.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAI99400.1 - 0.011 16.3 0.0 0.047 14.2 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_23 PF13489.1 OAI99400.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Mod_r PF07200.8 OAI99401.1 - 7.7e-14 51.8 3.4 2.8e-10 40.3 1.9 2.1 2 0 0 2 2 2 2 Modifier of rudimentary (Mod(r)) protein Herpes_UL14 PF03580.9 OAI99401.1 - 0.0022 17.8 1.6 0.0049 16.6 0.9 1.8 1 1 0 1 1 1 1 Herpesvirus UL14-like protein FlgN PF05130.7 OAI99401.1 - 0.024 14.9 1.0 0.024 14.9 0.7 2.2 1 1 1 2 2 2 0 FlgN protein TraI_2 PF07514.6 OAI99401.1 - 0.17 10.6 1.7 0.34 9.6 0.2 1.9 1 1 1 2 2 2 0 Putative helicase DUF972 PF06156.8 OAI99401.1 - 0.33 11.3 1.7 0.89 9.9 0.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Abhydrolase_6 PF12697.2 OAI99401.1 - 0.51 10.1 3.7 0.31 10.8 1.3 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family PRP3 PF08572.5 OAI99420.1 - 1.4e-61 207.7 5.9 2.5e-61 206.8 4.1 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 OAI99420.1 - 1.2e-27 96.1 0.0 2.5e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) TRAP-gamma PF07074.7 OAI99420.1 - 0.32 10.5 1.9 0.64 9.5 1.3 1.5 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) LSM PF01423.17 OAI99421.1 - 2.3e-14 52.6 0.0 3e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain gag-asp_proteas PF13975.1 OAI99447.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4414 PF14377.1 OAI99447.1 - 0.084 12.8 0.3 0.27 11.1 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4414) RVP PF00077.15 OAI99447.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease RVT_1 PF00078.22 OAI99448.1 - 1.6e-05 24.3 0.0 3.4e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sel1 PF08238.7 OAI99459.1 - 3.7e-35 119.5 32.4 5.2e-06 26.9 0.1 8.6 8 0 0 8 8 8 7 Sel1 repeat DUF1395 PF07160.7 OAI99459.1 - 0.06 12.8 0.9 0.099 12.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) OmpH PF03938.9 OAI99459.1 - 0.25 11.2 3.6 0.42 10.5 2.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TPR_6 PF13174.1 OAI99459.1 - 1.1 9.8 5.4 2.1 8.9 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Retrotrans_gag PF03732.12 OAI99470.1 - 2.1e-13 50.1 1.9 4e-13 49.2 0.4 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein RVP_2 PF08284.6 OAI99471.1 - 4.5e-09 36.3 0.0 7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI99471.1 - 0.0057 16.4 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAI99471.1 - 0.029 14.8 0.0 0.063 13.7 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.22 OAI99505.1 - 1.9e-10 40.4 0.0 4.8e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 OAI99505.1 - 2.5e-05 24.2 1.3 0.00025 21.0 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAI99505.1 - 5.1e-05 22.9 2.0 5.4e-05 22.9 0.5 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAI99505.1 - 0.004 16.6 0.5 0.009 15.4 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Uricase PF01014.13 OAI99511.1 - 1.9e-54 183.4 0.0 8.5e-34 116.6 0.0 2.6 2 1 0 2 2 2 2 Uricase ATP11 PF06644.6 OAI99512.1 - 1.4 8.3 18.4 2.7 7.3 12.7 1.5 1 0 0 1 1 1 0 ATP11 protein DUF1311 PF07007.7 OAI99512.1 - 3.9 7.6 9.7 7.5 6.7 6.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1311) DUF334 PF03904.8 OAI99512.1 - 4.3 6.5 10.5 6.5 6.0 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Thi4 PF01946.12 OAI99535.1 - 8.2e-15 54.5 0.1 5.4e-08 32.2 0.0 2.2 1 1 1 2 2 2 2 Thi4 family Malate_synthase PF01274.17 OAI99563.1 - 0.004 15.2 0.0 0.0044 15.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase MFS_1 PF07690.11 OAI99608.1 - 2.4e-33 115.3 12.0 2.4e-33 115.3 8.3 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAI99608.1 - 4.9e-10 38.5 0.4 4.9e-10 38.5 0.3 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter WD40 PF00400.27 OAI99609.1 - 5.4e-18 64.1 5.6 3.3e-06 26.7 0.0 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat RVT_2 PF07727.9 OAI99625.1 - 7.8e-61 205.1 0.0 1.1e-60 204.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI99625.1 - 1e-19 70.7 0.0 2.2e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain UBN2_2 PF14227.1 OAI99625.1 - 2.3e-16 59.4 0.1 2.2e-15 56.2 0.1 2.2 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAI99625.1 - 1.3e-10 41.0 0.2 2.7e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAI99625.1 - 1.7e-06 27.5 0.0 3.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain RVP PF00077.15 OAI99625.1 - 0.0041 16.9 0.0 0.0093 15.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.18 OAI99625.1 - 0.013 15.3 4.5 0.032 14.1 3.1 1.7 1 0 0 1 1 1 0 Zinc knuckle UBN2_3 PF14244.1 OAI99625.1 - 0.039 13.5 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type rve_3 PF13683.1 OAI99625.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain zf-CCHC_2 PF13696.1 OAI99625.1 - 0.13 11.7 1.6 0.4 10.2 1.1 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 OAI99636.1 - 5.2e-19 68.4 0.0 9.6e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAI99636.1 - 0.0012 19.3 0.1 0.0026 18.2 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI99636.1 - 0.028 14.3 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI99636.1 - 0.11 12.2 0.1 0.32 10.8 0.1 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Pyr_redox_2 PF07992.9 OAI99668.1 - 1.2e-26 93.8 0.1 9.9e-17 61.4 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAI99668.1 - 6.3e-12 45.7 0.1 8.5e-11 42.1 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAI99668.1 - 0.0013 18.7 0.1 0.15 12.0 0.0 3.3 3 2 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAI99668.1 - 0.24 10.2 4.2 0.62 8.9 0.0 3.0 2 2 2 4 4 4 0 FAD dependent oxidoreductase CITED PF04487.7 OAI99678.1 - 0.013 15.7 8.1 0.038 14.2 5.6 1.8 1 0 0 1 1 1 0 CITED AAA_32 PF13654.1 OAI99678.1 - 0.075 11.6 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DDE_3 PF13358.1 OAI99693.1 - 6.5e-28 97.3 0.0 1e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 OAI99693.1 - 0.0011 19.0 0.0 0.0036 17.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain DUF3123 PF11321.3 OAI99693.1 - 0.047 13.9 0.3 0.094 13.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Pyridoxal_deC PF00282.14 OAI99704.1 - 1.1e-76 257.6 0.0 3.9e-75 252.6 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 OAI99704.1 - 0.0008 18.6 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 OAI99704.1 - 0.044 12.5 0.0 0.061 12.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V CorA PF01544.13 OAI99751.1 - 2e-08 33.6 4.5 4.4e-08 32.5 3.1 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Sporozoite_P67 PF05642.6 OAI99751.1 - 4.7 4.9 7.9 7.1 4.3 5.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Epimerase PF01370.16 OAI99752.1 - 2.2e-39 135.3 0.0 3.2e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 OAI99752.1 - 1e-12 47.7 0.0 1.7e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 OAI99752.1 - 3.6e-12 45.5 0.0 1.3e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 OAI99752.1 - 2.2e-08 33.3 0.0 3.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 OAI99752.1 - 3.6e-08 32.6 0.1 5.9e-08 31.9 0.1 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 OAI99752.1 - 2.1e-07 30.9 0.0 4.1e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 OAI99752.1 - 9.4e-07 28.0 0.0 2e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 OAI99752.1 - 3.7e-06 27.0 0.0 0.00021 21.3 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 OAI99752.1 - 1.1e-05 25.1 0.0 3.1e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 KR domain Ribonuc_L-PSP PF01042.16 OAI99752.1 - 0.033 13.9 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 Endoribonuclease L-PSP Lyase_aromatic PF00221.14 OAI99767.1 - 0.00019 20.0 0.1 0.2 10.0 0.0 2.0 2 0 0 2 2 2 2 Aromatic amino acid lyase AAA_13 PF13166.1 OAI99768.1 - 0.0034 15.9 1.9 0.0037 15.8 1.3 1.0 1 0 0 1 1 1 1 AAA domain Spc7 PF08317.6 OAI99768.1 - 0.0048 15.6 1.2 0.0058 15.3 0.8 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Atg14 PF10186.4 OAI99768.1 - 0.0049 15.8 1.5 0.0061 15.5 1.1 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF3450 PF11932.3 OAI99768.1 - 0.0051 16.1 0.0 0.0054 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) HOOK PF05622.7 OAI99768.1 - 0.01 13.6 0.2 0.012 13.4 0.2 1.0 1 0 0 1 1 1 0 HOOK protein HAUS5 PF14817.1 OAI99768.1 - 0.011 14.3 0.1 0.012 14.2 0.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Fez1 PF06818.10 OAI99768.1 - 0.016 15.2 0.7 0.018 15.0 0.5 1.1 1 0 0 1 1 1 0 Fez1 ADIP PF11559.3 OAI99768.1 - 0.023 14.6 1.7 0.028 14.3 1.2 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HrpB7 PF09486.5 OAI99768.1 - 0.026 14.4 0.5 0.035 14.0 0.3 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) IncA PF04156.9 OAI99768.1 - 0.04 13.5 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 OAI99768.1 - 0.074 13.1 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FemAB PF02388.11 OAI99768.1 - 0.077 11.6 1.3 0.096 11.3 0.9 1.1 1 0 0 1 1 1 0 FemAB family DUF1910 PF08928.5 OAI99768.1 - 0.41 10.6 2.9 5.2 7.1 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1910) Med9 PF07544.8 OAI99768.1 - 0.44 10.3 3.7 1.3 8.8 2.5 1.8 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.15 OAI99768.1 - 0.44 10.3 3.6 3.5 7.4 2.0 1.9 1 1 1 2 2 2 0 Prefoldin subunit Methyltransf_2 PF00891.13 OAI99783.1 - 1.2e-11 44.2 0.0 2.1e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase DUF4413 PF14372.1 OAI99797.1 - 0.0011 18.8 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) SDA1 PF05285.7 OAI99797.1 - 2.5 7.3 14.8 0.23 10.7 5.6 2.0 2 0 0 2 2 2 0 SDA1 R3H PF01424.17 OAI99828.1 - 8.6e-12 44.5 0.0 2.4e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 R3H domain PfkB PF00294.19 OAI99840.1 - 0.00035 19.7 0.9 0.006 15.7 0.3 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Fasciclin PF02469.17 OAI99841.1 - 3e-06 27.2 0.0 1.2e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 Fasciclin domain 7TMR-HDED PF07697.6 OAI99841.1 - 0.075 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 7TM-HD extracellular zf-RING_2 PF13639.1 OAI99869.1 - 1.2e-10 41.0 5.3 5.4e-09 35.7 0.4 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 OAI99869.1 - 1.1e-06 28.5 0.4 1.1e-06 28.5 0.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAI99869.1 - 2e-05 24.2 2.7 5.4e-05 22.8 0.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 OAI99869.1 - 2.5e-05 23.8 3.0 0.00038 20.0 0.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 OAI99869.1 - 3.3e-05 23.8 0.7 0.00023 21.2 0.0 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 OAI99869.1 - 0.00014 21.4 4.5 0.00023 20.7 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAI99869.1 - 0.0037 16.9 0.3 0.0037 16.9 0.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING-like PF08746.6 OAI99869.1 - 0.013 15.5 0.4 0.026 14.5 0.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-Apc11 PF12861.2 OAI99869.1 - 0.034 13.9 0.2 0.034 13.9 0.2 1.6 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RAB3GAP2_N PF14655.1 OAI99869.1 - 0.06 12.3 2.1 0.11 11.4 1.4 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Rad50_zn_hook PF04423.9 OAI99869.1 - 0.074 12.5 2.3 0.58 9.6 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif FANCL_C PF11793.3 OAI99869.1 - 0.3 11.0 7.8 0.31 11.0 2.3 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 OAI99869.1 - 2.7 7.6 7.1 0.46 10.0 0.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.2 OAI99869.1 - 3 7.9 7.8 0.29 11.1 1.1 2.1 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.1 OAI99869.1 - 4.1 7.3 8.9 0.66 9.8 0.2 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 OAI99869.1 - 4.1 6.9 6.9 0.28 10.6 0.8 1.9 2 0 0 2 2 2 0 P-11 zinc finger Rtf2 PF04641.7 OAI99869.1 - 9.1 5.3 9.3 9 5.4 0.0 3.2 3 0 0 3 3 3 0 Rtf2 RING-finger Sugar_tr PF00083.19 OAI99883.1 - 2.3e-99 333.0 20.4 2.8e-99 332.7 14.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAI99883.1 - 1.3e-24 86.6 24.8 1.7e-23 82.9 13.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SR-25 PF10500.4 OAI99883.1 - 0.22 10.9 11.9 0.42 10.0 8.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BNIP3 PF06553.7 OAI99883.1 - 0.27 10.6 8.2 0.6 9.4 5.7 1.5 1 0 0 1 1 1 0 BNIP3 DUF2062 PF09835.4 OAI99899.1 - 0.0028 17.2 3.0 0.0048 16.5 2.1 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) DUF3366 PF11846.3 OAI99899.1 - 0.13 12.1 2.1 1.8 8.3 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3366) DUF2397 PF09660.5 OAI99902.1 - 0.00055 18.6 1.9 0.00058 18.5 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2397) AIP3 PF03915.8 OAI99902.1 - 0.001 18.0 3.8 0.0011 17.9 2.6 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 IncA PF04156.9 OAI99902.1 - 0.0015 18.1 5.8 0.0016 18.0 4.1 1.1 1 0 0 1 1 1 1 IncA protein Mei5 PF10376.4 OAI99902.1 - 0.0029 17.1 1.2 0.0035 16.8 0.9 1.1 1 0 0 1 1 1 1 Double-strand recombination repair protein Syntaxin-6_N PF09177.6 OAI99902.1 - 0.0073 16.6 4.8 0.011 16.1 3.3 1.3 1 0 0 1 1 1 1 Syntaxin 6, N-terminal Dor1 PF04124.7 OAI99902.1 - 0.015 13.7 2.0 0.017 13.5 1.4 1.1 1 0 0 1 1 1 0 Dor1-like family FH2 PF02181.18 OAI99902.1 - 0.017 14.0 2.1 0.021 13.7 1.5 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF4015 PF13200.1 OAI99902.1 - 0.017 14.0 0.6 0.018 13.9 0.4 1.1 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain CENP-K PF11802.3 OAI99902.1 - 0.025 13.8 2.6 0.024 13.8 1.8 1.1 1 0 0 1 1 1 0 Centromere-associated protein K AAA_13 PF13166.1 OAI99902.1 - 0.032 12.7 3.7 0.032 12.7 2.5 1.0 1 0 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.4 OAI99902.1 - 0.034 14.0 6.4 0.033 14.0 4.0 1.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 OAI99902.1 - 0.048 11.3 8.8 0.052 11.2 6.1 1.0 1 0 0 1 1 1 0 Myosin tail FlxA PF14282.1 OAI99902.1 - 0.08 12.8 6.2 0.13 12.2 4.3 1.4 1 0 0 1 1 1 0 FlxA-like protein DUF2205 PF10224.4 OAI99902.1 - 0.098 12.2 6.4 0.28 10.8 3.2 2.1 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) Seryl_tRNA_N PF02403.17 OAI99902.1 - 0.11 12.5 7.6 0.15 12.1 5.3 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Erp_C PF06780.6 OAI99902.1 - 0.11 12.3 5.1 0.11 12.3 2.6 1.6 1 1 0 2 2 2 0 Erp protein C-terminus Peptidase_S49_N PF08496.5 OAI99902.1 - 0.13 12.0 5.9 0.17 11.6 4.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Spc24 PF08286.6 OAI99902.1 - 0.13 11.9 5.2 0.19 11.4 3.6 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 OmpH PF03938.9 OAI99902.1 - 0.14 12.0 6.2 0.15 11.9 4.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.10 OAI99902.1 - 0.19 10.9 4.2 0.21 10.7 2.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FemAB PF02388.11 OAI99902.1 - 0.21 10.2 3.2 0.28 9.8 2.3 1.2 1 0 0 1 1 1 0 FemAB family TPR_MLP1_2 PF07926.7 OAI99902.1 - 0.22 11.2 6.8 0.31 10.7 4.7 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 OAI99902.1 - 0.23 10.3 8.0 0.23 10.3 5.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 OAI99902.1 - 0.24 9.2 3.3 0.26 9.0 2.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3734 PF12536.3 OAI99902.1 - 0.33 11.0 3.2 0.62 10.2 2.1 1.6 1 1 1 2 2 2 0 Patatin phospholipase Mnd1 PF03962.10 OAI99902.1 - 0.41 10.2 5.3 0.52 9.9 3.7 1.2 1 0 0 1 1 1 0 Mnd1 family DUF972 PF06156.8 OAI99902.1 - 0.48 10.8 3.1 0.58 10.5 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF342 PF03961.8 OAI99902.1 - 0.67 8.2 4.6 0.72 8.1 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Phage_Gp23 PF10669.4 OAI99902.1 - 0.73 9.9 5.0 0.87 9.7 3.1 1.5 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF3186 PF11382.3 OAI99902.1 - 1.2 8.2 4.7 1.5 7.8 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Lge1 PF11488.3 OAI99902.1 - 1.4 9.1 4.6 1.7 8.8 2.9 1.4 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 Cortex-I_coil PF09304.5 OAI99902.1 - 1.7 8.6 9.4 2.1 8.4 5.3 1.8 1 1 1 2 2 2 0 Cortexillin I, coiled coil Pox_A_type_inc PF04508.7 OAI99902.1 - 8.2 6.5 6.7 0.84 9.5 0.9 2.4 2 1 0 2 2 1 0 Viral A-type inclusion protein repeat HALZ PF02183.13 OAI99948.1 - 0.00014 21.4 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF4201 PF13870.1 OAI99948.1 - 0.089 12.2 0.1 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Cytochrom_B561 PF03188.11 OAI99962.1 - 9.9e-08 31.9 11.3 9.9e-08 31.9 7.9 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.12 OAI99962.1 - 1.4e-05 25.0 1.5 2.6e-05 24.1 0.8 1.7 1 1 1 2 2 2 1 DOMON domain DUF2427 PF10348.4 OAI99962.1 - 0.015 14.8 4.7 0.072 12.6 3.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) Vps16_C PF04840.7 OAI99995.1 - 2.5e-67 227.0 1.4 2.1e-36 125.5 0.0 3.1 3 0 0 3 3 3 3 Vps16, C-terminal region Vps16_N PF04841.8 OAI99995.1 - 9.6e-35 119.8 0.0 8e-21 74.0 0.0 3.1 3 0 0 3 3 3 3 Vps16, N-terminal region RVT_1 PF00078.22 OAJ00013.1 - 6.9e-17 61.5 0.0 1.2e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ00013.1 - 0.00038 20.9 0.0 0.00085 19.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ00013.1 - 0.0075 16.0 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ00013.1 - 0.0097 15.8 0.0 0.036 13.9 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease 4HBT_3 PF13622.1 OAJ00028.1 - 4.5e-32 111.7 1.0 6.1e-32 111.3 0.7 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 OAJ00028.1 - 0.00023 20.8 0.0 0.00048 19.7 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA thioesterase DPBB_1 PF03330.13 OAJ00029.1 - 1.3e-07 31.5 0.1 1.3e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ00029.1 - 0.0021 17.7 0.9 0.0047 16.5 0.6 1.6 1 0 0 1 1 1 1 Barwin family Neisseria_TspB PF05616.8 OAJ00029.1 - 0.083 11.2 4.4 0.1 10.9 3.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF1180 PF06679.7 OAJ00029.1 - 0.28 11.0 9.6 0.073 12.9 4.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF737 PF05300.6 OAJ00029.1 - 0.67 9.8 7.6 1.1 9.2 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) FNIP_N PF14636.1 OAJ00029.1 - 0.78 10.2 7.8 2.1 8.8 5.5 1.7 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Mito_fiss_reg PF05308.6 OAJ00029.1 - 5.3 6.3 13.4 8.7 5.6 9.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4551 PF15087.1 OAJ00029.1 - 7.9 4.7 10.2 10 4.3 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MCPVI PF02993.9 OAJ00029.1 - 8.4 6.4 11.0 14 5.7 7.6 1.3 1 0 0 1 1 1 0 Minor capsid protein VI HEAT_2 PF13646.1 OAJ00077.1 - 8.6e-07 29.1 1.3 1.5e-06 28.3 0.9 1.3 1 0 0 1 1 1 1 HEAT repeats Tetraspannin PF00335.15 OAJ00077.1 - 0.02 14.1 0.1 0.037 13.3 0.1 1.3 1 0 0 1 1 1 0 Tetraspanin family ATG22 PF11700.3 OAJ00077.1 - 0.048 12.1 0.4 0.059 11.8 0.3 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like HEAT PF02985.17 OAJ00077.1 - 0.1 12.7 0.3 1.5 9.0 0.1 2.5 2 0 0 2 2 2 0 HEAT repeat DUF3492 PF11997.3 OAJ00079.1 - 1.2e-89 300.4 0.0 1.4e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) Glycos_transf_1 PF00534.15 OAJ00079.1 - 5.2e-21 74.8 0.0 8.6e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 OAJ00079.1 - 9.2e-12 45.2 0.1 2.5e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 OAJ00079.1 - 0.00013 22.1 1.3 0.00022 21.4 0.3 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 OAJ00079.1 - 0.0025 17.5 0.0 0.0069 16.1 0.0 1.7 1 1 1 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 OAJ00079.1 - 0.064 13.5 0.0 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferases group 1 UBA PF00627.26 OAJ00094.1 - 7.6e-07 28.7 0.0 2.4e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain WEMBL PF05701.6 OAJ00094.1 - 0.037 12.4 13.1 0.06 11.8 9.1 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light FliJ PF02050.11 OAJ00094.1 - 0.095 12.7 4.1 0.05 13.6 1.1 1.7 1 1 1 2 2 2 0 Flagellar FliJ protein EzrA PF06160.7 OAJ00094.1 - 0.18 9.9 3.2 0.3 9.2 2.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF812 PF05667.6 OAJ00094.1 - 0.25 9.8 6.3 0.34 9.3 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ATG16 PF08614.6 OAJ00094.1 - 0.57 9.9 8.5 1.3 8.8 5.9 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc7 PF08317.6 OAJ00094.1 - 0.59 8.7 5.4 0.83 8.2 3.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 OAJ00094.1 - 0.84 9.4 16.7 0.26 11.1 5.8 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 OAJ00094.1 - 1.4 6.1 6.8 2 5.6 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.3 OAJ00094.1 - 1.5 8.7 5.7 2.5 7.9 3.4 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.10 OAJ00094.1 - 4 7.4 15.1 8.6 6.3 10.4 1.5 1 1 0 1 1 1 0 Fez1 DUF972 PF06156.8 OAJ00094.1 - 5.1 7.4 5.8 7.4 6.9 1.8 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Atg14 PF10186.4 OAJ00094.1 - 9.2 5.1 8.5 15 4.3 5.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 KH_1 PF00013.24 OAJ00131.1 - 1e-08 34.6 0.0 6.6e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 OAJ00131.1 - 7.3e-05 22.3 0.8 0.0031 17.1 0.0 2.5 2 0 0 2 2 2 1 KH domain Trp_repressor PF01371.14 OAJ00131.1 - 0.04 13.8 0.1 0.089 12.7 0.1 1.5 1 0 0 1 1 1 0 Trp repressor protein DUF4218 PF13960.1 OAJ00147.1 - 0.00049 19.5 0.0 0.00089 18.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Histone PF00125.19 OAJ00149.1 - 1.8e-27 95.2 0.6 2.9e-27 94.5 0.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ00149.1 - 1.8e-05 24.8 0.0 2.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAJ00149.1 - 0.00039 20.4 0.1 0.00078 19.4 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 OAJ00149.1 - 0.049 12.8 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DNA_pol_phi PF04931.8 OAJ00155.1 - 2.1e-30 105.2 30.4 3e-20 71.6 19.9 3.0 3 0 0 3 3 3 2 DNA polymerase phi CRISPR_Cse2 PF09485.5 OAJ00155.1 - 0.014 15.4 1.8 0.041 13.9 1.2 1.8 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) SGT1 PF07093.6 OAJ00155.1 - 4.6 5.5 19.9 0.96 7.7 10.6 2.1 2 1 0 2 2 2 0 SGT1 protein RRM_1 PF00076.17 OAJ00172.1 - 1.9e-79 261.2 2.0 5.2e-19 67.6 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ00172.1 - 1.5e-53 178.6 5.0 1.1e-15 57.3 0.0 4.5 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ00172.1 - 4.2e-42 141.7 5.4 2.3e-12 46.5 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 OAJ00172.1 - 5.7e-29 99.6 0.5 7.2e-28 96.0 0.3 2.9 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 OAJ00172.1 - 8.1e-07 28.7 0.5 0.87 9.4 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 OAJ00172.1 - 0.017 14.8 3.4 4.3 7.1 0.1 3.8 4 0 0 4 4 4 0 Limkain b1 CbiG_mid PF11761.3 OAJ00172.1 - 0.018 15.2 4.2 4.2 7.6 0.0 4.1 4 0 0 4 4 4 0 Cobalamin biosynthesis central region CPSF100_C PF13299.1 OAJ00172.1 - 6.5 6.9 6.5 1.6 8.8 1.7 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PQ-loop PF04193.9 OAJ00202.1 - 3.8e-14 51.9 0.2 8.9e-14 50.7 0.1 1.6 1 0 0 1 1 1 1 PQ loop repeat WWbp PF10349.4 OAJ00202.1 - 0.67 10.8 10.7 0.18 12.6 3.5 2.3 2 0 0 2 2 2 0 WW-domain ligand protein AMP-binding PF00501.23 OAJ00214.1 - 2.6e-21 75.5 0.7 2.4e-19 69.0 0.5 2.5 2 1 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.7 OAJ00214.1 - 7.4e-14 51.2 0.0 1.6e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 OAJ00214.1 - 3.6e-07 29.8 0.0 7.7e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 OAJ00214.1 - 5e-06 26.5 0.2 4.9e-05 23.2 0.1 2.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ00214.1 - 0.00063 19.4 0.1 0.0055 16.3 0.0 2.6 2 1 0 2 2 2 1 KR domain PP-binding PF00550.20 OAJ00214.1 - 0.019 15.2 0.0 0.16 12.2 0.0 2.3 1 1 0 1 1 1 0 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 OAJ00214.1 - 0.14 10.9 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TPR_11 PF13414.1 OAJ00228.1 - 1.9e-12 46.6 1.2 2.6e-06 26.9 0.2 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 OAJ00228.1 - 3.4e-07 29.6 0.7 8.7e-05 22.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ00228.1 - 2.4e-06 26.8 0.9 0.00017 21.0 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ00228.1 - 0.0027 17.3 0.0 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ00228.1 - 0.018 14.8 0.0 0.018 14.8 0.0 2.6 2 1 2 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 OAJ00228.1 - 0.54 10.1 0.0 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.1 OAJ00228.1 - 1.1 10.0 0.0 1.1 10.0 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ00229.1 - 3.5e-08 33.6 0.8 0.0029 17.9 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ00229.1 - 4.1e-07 30.4 3.0 0.006 17.2 0.0 4.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ00229.1 - 2.5e-05 24.4 5.6 0.18 12.5 0.0 5.2 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ00229.1 - 4.8e-05 23.5 0.1 0.0045 17.3 0.0 3.7 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ00229.1 - 7.7e-05 22.3 0.0 0.011 15.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ00229.1 - 0.00017 21.1 0.3 0.029 14.0 0.0 2.9 3 1 0 3 3 3 1 TPR repeat TPR_12 PF13424.1 OAJ00229.1 - 0.00061 19.6 1.7 0.11 12.4 0.0 3.7 2 2 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ00229.1 - 0.003 17.6 0.0 0.55 10.4 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 OAJ00229.1 - 0.011 15.4 0.0 1.7 8.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ00229.1 - 0.013 15.8 0.1 1.2 9.7 0.0 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.2 OAJ00229.1 - 0.023 14.7 0.5 5.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_10 PF13374.1 OAJ00229.1 - 0.042 13.7 0.4 0.042 13.7 0.3 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ00229.1 - 0.11 12.1 0.0 4.6 7.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Thaumatin PF00314.12 OAJ00244.1 - 4.5e-19 68.7 4.4 1.1e-18 67.4 3.1 1.6 1 1 0 1 1 1 1 Thaumatin family adh_short_C2 PF13561.1 OAJ00274.1 - 6.2e-11 42.5 0.0 7.8e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.1 OAJ00275.1 - 2.6e-17 63.0 0.1 3.7e-17 62.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ00275.1 - 0.00097 18.7 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ00275.1 - 0.011 16.2 0.0 0.036 14.5 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ00275.1 - 0.025 15.0 0.0 0.25 11.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_21 PF05050.7 OAJ00276.1 - 2.2e-23 83.0 0.0 3.4e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_18 PF12847.2 OAJ00276.1 - 1.1e-07 32.4 0.0 2.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 OAJ00276.1 - 3.9e-07 29.8 0.0 6.5e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein V_cholerae_RfbT PF05575.6 OAJ00276.1 - 8.9e-05 21.6 0.0 0.00016 20.8 0.0 1.3 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein Methyltransf_4 PF02390.12 OAJ00276.1 - 0.0021 17.1 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 OAJ00276.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 OAJ00276.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.16 OAJ00277.1 - 4.3e-39 134.3 0.0 5.1e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 OAJ00277.1 - 1.6e-10 40.3 0.0 1.2e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 OAJ00277.1 - 7.4e-08 31.6 0.0 1.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 OAJ00277.1 - 0.00067 18.4 0.0 0.00081 18.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 OAJ00277.1 - 0.0012 18.9 0.0 0.0029 17.6 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 OAJ00277.1 - 0.0064 16.4 0.1 0.088 12.7 0.0 2.7 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 OAJ00277.1 - 0.021 13.7 0.0 0.15 10.9 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Glyco_trans_2_3 PF13632.1 OAJ00293.1 - 5e-05 23.0 0.0 6.8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Mucin PF01456.12 OAJ00313.1 - 0.00016 21.4 25.7 0.00016 21.4 17.8 3.3 3 0 0 3 3 3 2 Mucin-like glycoprotein SCIMP PF15050.1 OAJ00313.1 - 0.091 12.6 0.4 0.52 10.2 0.0 2.2 1 1 0 2 2 2 0 SCIMP protein CKS PF01111.14 OAJ00332.1 - 3.3e-35 119.7 0.1 4.1e-35 119.4 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ATP-synt_10 PF05176.9 OAJ00333.1 - 4.9e-47 160.3 0.0 1.5e-30 106.3 0.0 2.1 2 0 0 2 2 2 2 ATP10 protein Abhydrolase_6 PF12697.2 OAJ00333.1 - 0.12 12.2 3.2 0.14 11.9 1.1 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Ras PF00071.17 OAJ00334.1 - 1.1e-56 190.6 0.0 1.4e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ00334.1 - 1.7e-19 70.4 0.0 2.5e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ00334.1 - 9.9e-17 60.7 0.0 8.7e-16 57.6 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ00334.1 - 2.6e-07 30.0 0.0 3.4e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 OAJ00334.1 - 3.1e-05 23.4 0.0 4.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ00334.1 - 0.0014 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 OAJ00334.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Cu-oxidase_3 PF07732.10 OAJ00356.1 - 5.5e-28 97.0 3.3 1.1e-26 92.8 0.1 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 OAJ00356.1 - 3.2e-15 56.3 0.0 6.7e-14 52.0 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAJ00356.1 - 1e-14 54.1 9.9 3.4e-11 42.8 2.5 3.5 2 2 0 2 2 2 2 Multicopper oxidase MIP PF00230.15 OAJ00376.1 - 1.5e-08 34.4 8.4 2.4e-08 33.7 5.8 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF4449 PF14613.1 OAJ00392.1 - 0.0011 18.9 7.6 0.0024 17.7 0.0 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF4449) DUF1910 PF08928.5 OAJ00392.1 - 0.0021 18.0 0.4 0.47 10.4 0.0 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF1910) Phage_connect_1 PF05135.8 OAJ00392.1 - 0.099 12.8 1.3 1.1 9.4 0.5 2.6 1 1 1 2 2 2 0 Phage gp6-like head-tail connector protein DDE_1 PF03184.14 OAJ00407.1 - 1.3e-28 99.5 0.1 1.3e-27 96.3 0.0 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 OAJ00407.1 - 0.00013 21.7 2.3 0.0022 17.7 0.0 3.4 2 1 1 3 3 3 2 DDE superfamily endonuclease DDHD PF02862.12 OAJ00407.1 - 3 7.5 7.2 6.9 6.3 5.0 1.5 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 OAJ00407.1 - 3.7 7.4 7.3 7.9 6.3 4.9 1.6 2 0 0 2 2 2 0 GAGA binding protein-like family Ycf1 PF05758.7 OAJ00407.1 - 8.7 3.9 10.0 12 3.4 6.9 1.1 1 0 0 1 1 1 0 Ycf1 DDE_3 PF13358.1 OAJ00420.1 - 9.3e-29 100.0 0.0 1.3e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 OAJ00420.1 - 5.8e-05 23.1 0.0 0.00012 22.1 0.0 1.8 1 1 0 1 1 1 1 Integrase core domain HTH_29 PF13551.1 OAJ00420.1 - 0.016 15.3 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_7 PF02796.10 OAJ00420.1 - 0.068 13.0 0.0 0.41 10.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase TarH PF02203.10 OAJ00441.1 - 0.051 13.4 0.0 0.062 13.1 0.0 1.1 1 0 0 1 1 1 0 Tar ligand binding domain homologue Glyco_hydro_18 PF00704.23 OAJ00442.1 - 1.2e-38 133.5 0.0 1.4e-38 133.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 tRNA-synt_1 PF00133.17 OAJ00463.1 - 1.5e-105 353.5 0.0 2.7e-105 352.6 0.0 1.3 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 OAJ00463.1 - 7.5e-23 80.9 0.0 1.5e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 OAJ00463.1 - 3.9e-07 29.0 0.0 0.00027 19.7 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 OAJ00463.1 - 0.02 14.0 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain UBN2 PF14223.1 OAJ00516.1 - 0.0021 17.8 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ00516.1 - 0.03 14.2 8.3 0.064 13.2 5.8 1.6 1 0 0 1 1 1 0 Zinc knuckle HTH_23 PF13384.1 OAJ00571.1 - 0.00098 18.7 0.0 0.0091 15.6 0.0 2.5 3 0 0 3 3 3 1 Homeodomain-like domain CPSase_L_D3 PF02787.14 OAJ00571.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain WW PF00397.21 OAJ00607.1 - 4e-08 32.9 1.6 0.0014 18.3 0.1 2.5 2 0 0 2 2 2 2 WW domain Cation_efflux PF01545.16 OAJ00631.1 - 4e-26 91.7 4.9 4e-26 91.7 3.4 3.2 3 2 0 3 3 3 1 Cation efflux family DUF1713 PF08213.6 OAJ00632.1 - 4.5e-10 38.9 24.2 7.8e-10 38.1 16.8 1.4 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) TSA PF03249.8 OAJ00632.1 - 0.13 10.7 8.1 0.16 10.4 5.6 1.1 1 0 0 1 1 1 0 Type specific antigen DDHD PF02862.12 OAJ00632.1 - 0.33 10.6 6.8 0.41 10.4 4.7 1.1 1 0 0 1 1 1 0 DDHD domain SOBP PF15279.1 OAJ00632.1 - 1.1 9.6 10.8 1.2 9.4 7.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Protamine_P2 PF00841.14 OAJ00632.1 - 8.4 7.0 14.7 19 5.8 10.2 1.6 1 1 0 1 1 1 0 Sperm histone P2 ABC_tran_2 PF12848.2 OAJ00632.1 - 8.5 6.2 13.3 13 5.6 9.2 1.3 1 0 0 1 1 1 0 ABC transporter RVT_1 PF00078.22 OAJ00656.1 - 7.9e-16 58.0 0.0 1.5e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ00656.1 - 2.9e-15 56.4 0.0 6.4e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain GATase_4 PF13230.1 OAJ00690.1 - 7.5e-19 67.4 0.0 2.2e-18 65.9 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 OAJ00690.1 - 9.4e-10 38.5 0.0 4.2e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 OAJ00690.1 - 4.6e-08 32.1 0.1 5.5e-07 28.6 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferases class-II DUF1454 PF07305.7 OAJ00690.1 - 0.077 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) Chromo PF00385.19 OAJ00692.1 - 9.4e-07 28.4 0.0 2.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.20 OAJ00709.1 - 2.7e-73 246.3 0.0 3.2e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ00709.1 - 1.3e-33 116.1 0.0 3.3e-33 114.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ00709.1 - 0.0023 16.9 0.0 0.005 15.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ00709.1 - 0.0028 16.7 0.1 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ00709.1 - 0.066 12.9 0.1 0.2 11.3 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pex14_N PF04695.8 OAJ00731.1 - 1.9 8.5 6.5 1.1 9.3 0.1 2.3 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RVT_1 PF00078.22 OAJ00748.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.13 OAJ00774.1 - 0.022 13.9 0.1 0.13 11.5 0.0 2.2 3 0 0 3 3 3 0 DNA polymerase (viral) C-terminal domain RVT_1 PF00078.22 OAJ00774.1 - 0.063 12.6 0.0 0.23 10.8 0.0 2.0 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.17 OAJ00775.1 - 6.8e-05 22.6 0.0 9.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family TRAM_LAG1_CLN8 PF03798.11 OAJ00795.1 - 4.6e-06 26.3 10.3 7.6e-06 25.6 7.1 1.3 1 0 0 1 1 1 1 TLC domain TFIIA PF03153.8 OAJ00795.1 - 0.0022 17.9 12.3 0.0022 17.9 8.5 2.4 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF1034 PF06280.7 OAJ00815.1 - 3.8e-09 36.9 0.1 5.9e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) DUF4232 PF14016.1 OAJ00815.1 - 0.074 12.7 1.2 0.11 12.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) GLE1 PF07817.8 OAJ00837.1 - 2.5e-62 210.1 0.0 3.8e-62 209.5 0.0 1.3 1 0 0 1 1 1 1 GLE1-like protein Spore_coat_CotO PF14153.1 OAJ00837.1 - 0.038 13.4 12.4 0.069 12.5 8.6 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Macoilin PF09726.4 OAJ00837.1 - 0.34 9.1 15.2 0.49 8.6 10.6 1.3 1 0 0 1 1 1 0 Transmembrane protein RR_TM4-6 PF06459.7 OAJ00837.1 - 2.4 7.9 14.0 5.3 6.8 9.7 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Snf7 PF03357.16 OAJ00838.1 - 1e-16 60.7 11.2 1.2e-16 60.6 7.8 1.0 1 0 0 1 1 1 1 Snf7 SYCE1 PF15233.1 OAJ00838.1 - 0.0038 17.1 2.7 0.0058 16.5 1.9 1.3 1 1 0 1 1 1 1 Synaptonemal complex central element protein 1 IMP_cyclohyd PF07826.6 OAJ00838.1 - 0.079 12.2 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein Ist1 PF03398.9 OAJ00838.1 - 0.086 12.2 1.8 0.11 11.8 1.2 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway YlqD PF11068.3 OAJ00838.1 - 0.36 10.8 5.0 0.48 10.4 0.8 2.1 1 1 0 2 2 2 0 YlqD protein ABC1 PF03109.11 OAJ00859.1 - 7.4e-26 90.4 0.0 1.5e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Oxidored-like PF09791.4 OAJ00859.1 - 6.8e-18 63.8 1.5 1.7e-17 62.5 1.0 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Dimer_Tnp_hAT PF05699.9 OAJ00880.1 - 3.4e-11 42.6 0.0 9.2e-11 41.2 0.0 1.8 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAJ00880.1 - 0.0051 16.7 0.0 0.019 14.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) Sec23_helical PF04815.10 OAJ00904.1 - 5.6e-25 86.7 0.5 1e-24 85.9 0.4 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 OAJ00904.1 - 8.6e-09 34.9 0.0 2.4e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat DUF3429 PF11911.3 OAJ00905.1 - 5.8e-38 130.0 16.1 8.5e-38 129.5 11.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) MULE PF10551.4 OAJ00930.1 - 6.3e-09 35.8 1.2 1.9e-07 31.1 0.4 2.9 2 1 0 2 2 2 1 MULE transposase domain HsbA PF12296.3 OAJ00945.1 - 3.6e-15 55.9 13.7 5.6e-15 55.2 9.5 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A bZIP_1 PF00170.16 OAJ00968.1 - 3.6e-08 33.2 5.8 3.6e-08 33.2 4.0 2.3 2 1 0 2 2 2 1 bZIP transcription factor FUSC PF04632.7 OAJ00968.1 - 0.068 11.5 1.2 0.12 10.8 0.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family UCR_14kD PF02271.11 OAJ00968.1 - 0.07 12.9 0.4 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit bZIP_2 PF07716.10 OAJ00968.1 - 0.11 12.3 8.6 0.33 10.8 3.1 2.6 1 1 1 2 2 2 0 Basic region leucine zipper FA_desaturase PF00487.19 OAJ00969.1 - 1e-12 48.0 6.0 1.5e-12 47.4 4.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3947 PF13135.1 OAJ00969.1 - 0.046 13.9 3.7 0.08 13.1 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) CCER1 PF15482.1 OAJ00970.1 - 5.4 6.5 11.2 0.21 11.2 2.4 2.2 2 1 0 2 2 2 0 Coiled-coil domain-containing glutamate-rich protein family 1 DDE_Tnp_4 PF13359.1 OAJ00993.1 - 7.5e-23 80.8 0.0 1.4e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Alb1 PF09135.6 OAJ00994.1 - 0.09 13.4 7.1 0.18 12.4 4.9 1.5 1 0 0 1 1 1 0 Alb1 Asp PF00026.18 OAJ01019.1 - 2.1e-37 129.0 0.0 3.6e-37 128.3 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ01019.1 - 3.9e-07 30.1 0.3 9.8e-07 28.8 0.1 1.7 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal DUF4315 PF14193.1 OAJ01042.1 - 0.13 12.2 0.4 0.16 11.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) hGDE_N PF14699.1 OAJ01062.1 - 0.14 11.9 0.3 0.59 10.0 0.0 2.0 1 1 1 2 2 2 0 N-terminal domain from the human glycogen debranching enzyme RVT_1 PF00078.22 OAJ01064.1 - 4.6e-17 62.0 0.0 1.1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ01064.1 - 2.9e-14 53.1 0.0 1.5e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Aa_trans PF01490.13 OAJ01105.1 - 4.3e-85 285.6 5.6 5.5e-85 285.3 3.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ResIII PF04851.10 OAJ01127.1 - 1.9e-16 60.4 0.0 4e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ01127.1 - 1.2e-12 47.6 0.0 2.2e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ01127.1 - 9.5e-12 44.6 0.0 2.2e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 OAJ01127.1 - 0.0017 17.2 0.0 0.0027 16.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 OAJ01127.1 - 0.0021 18.2 0.0 0.0053 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 OAJ01127.1 - 0.0026 16.6 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 OAJ01127.1 - 0.0031 17.5 0.2 0.01 15.8 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 OAJ01127.1 - 0.037 13.6 2.1 4.8 6.6 0.0 3.0 2 1 1 3 3 3 0 AAA domain Helicase_C PF00271.26 OAJ01129.1 - 2.3e-07 30.5 0.0 1.3e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 OAJ01129.1 - 0.024 14.5 1.0 5.9 6.8 0.0 2.8 2 1 1 3 3 3 0 Helicase C-terminal domain DUF755 PF05501.6 OAJ01129.1 - 2 8.4 13.3 1.1 9.2 7.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF755) RVT_3 PF13456.1 OAJ01155.1 - 2e-05 24.2 0.3 6.9e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase-like TMCO5 PF14992.1 OAJ01155.1 - 0.48 9.5 4.4 0.77 8.8 3.0 1.2 1 0 0 1 1 1 0 TMCO5 family DUF2236 PF09995.4 OAJ01193.1 - 1.9e-21 76.4 0.3 5.2e-20 71.7 0.0 3.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF500 PF04366.7 OAJ01215.1 - 1.7e-43 147.0 1.0 1e-41 141.3 0.1 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF500) zf-CCHC PF00098.18 OAJ01235.1 - 6.3e-05 22.7 0.6 8.9e-05 22.2 0.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ01235.1 - 0.0013 18.4 0.6 0.0024 17.5 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle rve PF00665.21 OAJ01236.1 - 5.4e-17 62.0 0.0 1.4e-16 60.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ01236.1 - 5.9e-08 32.3 0.0 7.7e-07 28.6 0.0 2.2 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 OAJ01236.1 - 7.2e-07 29.2 0.0 1.5e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAJ01236.1 - 6.1e-05 23.4 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ01236.1 - 0.00026 20.7 0.0 0.00082 19.1 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease NMO PF03060.10 OAJ01278.1 - 9.1e-70 235.4 3.6 1.1e-69 235.1 2.5 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 OAJ01278.1 - 8.5e-05 21.5 2.6 0.00016 20.6 1.8 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 OAJ01278.1 - 0.00018 20.5 4.6 0.0012 17.7 3.2 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain IF2_N PF04760.10 OAJ01278.1 - 0.025 14.2 0.0 0.071 12.7 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region FAA_hydrolase PF01557.13 OAJ01279.1 - 5.9e-54 182.8 0.0 7.7e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family NRDE PF05742.7 OAJ01297.1 - 1.7e-27 96.4 0.0 1.7e-26 93.1 0.0 2.5 1 1 0 1 1 1 1 NRDE protein Sad1_UNC PF07738.8 OAJ01298.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal COPI_C PF06957.6 OAJ01322.1 - 0.14 10.6 3.9 0.22 10.0 2.7 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Nop14 PF04147.7 OAJ01322.1 - 1.4 6.7 12.7 1.9 6.3 8.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 OAJ01322.1 - 2.6 7.2 17.2 3.9 6.6 11.9 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.8 OAJ01322.1 - 4.5 4.9 16.2 6.2 4.4 11.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Syntaxin-6_N PF09177.6 OAJ01324.1 - 0.15 12.4 0.1 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Tsp45I PF06300.7 OAJ01324.1 - 0.17 11.2 0.0 3.8 6.8 0.0 2.0 1 1 0 1 1 1 0 Tsp45I type II restriction enzyme DUF3275 PF11679.3 OAJ01377.1 - 0.71 9.4 4.1 0.86 9.1 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) RAP1 PF07218.6 OAJ01377.1 - 4.2 5.3 8.5 4.9 5.1 5.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ycf1 PF05758.7 OAJ01378.1 - 0.016 12.9 4.1 0.016 12.9 2.9 1.0 1 0 0 1 1 1 0 Ycf1 Nop14 PF04147.7 OAJ01378.1 - 0.021 12.7 10.3 0.028 12.3 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family PIH1 PF08190.7 OAJ01378.1 - 0.043 13.2 9.8 0.049 13.0 6.8 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 eIF-3_zeta PF05091.7 OAJ01378.1 - 0.048 12.2 6.9 0.059 11.9 4.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Paf1 PF03985.8 OAJ01378.1 - 0.074 11.7 12.3 0.093 11.4 8.5 1.1 1 0 0 1 1 1 0 Paf1 Spt5_N PF11942.3 OAJ01378.1 - 0.12 13.0 13.8 0.19 12.3 9.6 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.9 OAJ01378.1 - 0.17 9.8 11.4 0.22 9.4 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.1 OAJ01378.1 - 0.19 10.1 5.3 0.23 9.9 3.7 1.1 1 0 0 1 1 1 0 Raftlin Plasmodium_Vir PF05795.6 OAJ01378.1 - 0.34 10.0 2.1 0.35 10.0 1.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3513 PF12026.3 OAJ01378.1 - 0.34 10.4 8.9 0.46 10.0 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) SUFU_C PF12470.3 OAJ01378.1 - 0.87 9.1 4.3 0.96 9.0 2.6 1.3 1 1 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain Ebola_NP PF05505.7 OAJ01378.1 - 0.98 7.3 11.4 1.2 7.1 7.9 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DUF853 PF05872.7 OAJ01378.1 - 1 7.6 5.7 1.4 7.1 3.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF605 PF04652.11 OAJ01378.1 - 1.3 8.3 21.6 1.7 7.9 15.0 1.1 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 OAJ01378.1 - 1.3 8.6 13.3 1.9 8.1 9.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.2 OAJ01378.1 - 2.4 5.7 11.1 2.8 5.4 7.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Menin PF05053.8 OAJ01378.1 - 2.6 6.1 9.4 2.9 5.9 6.5 1.0 1 0 0 1 1 1 0 Menin DUF4557 PF15101.1 OAJ01378.1 - 3 7.6 11.7 4.5 7.0 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) eIF3_subunit PF08597.5 OAJ01378.1 - 3.3 7.1 13.0 4.8 6.6 9.0 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PAT1 PF09770.4 OAJ01378.1 - 3.5 5.7 28.4 4.2 5.5 19.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MCPVI PF02993.9 OAJ01378.1 - 5.7 7.0 19.5 8.3 6.4 13.3 1.4 1 1 0 1 1 1 0 Minor capsid protein VI NARP1 PF12569.3 OAJ01378.1 - 5.8 5.5 10.4 7.4 5.1 7.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Apt1 PF10351.4 OAJ01378.1 - 5.9 5.6 9.3 2.4 6.9 5.0 1.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain Nop53 PF07767.6 OAJ01378.1 - 6.8 5.5 19.6 9.5 5.0 13.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.7 OAJ01402.1 - 0.17 9.8 11.6 0.28 9.0 8.0 1.4 1 0 0 1 1 1 0 Nop14-like family Dimer_Tnp_hAT PF05699.9 OAJ01442.1 - 7.1e-13 47.9 0.0 1.7e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAJ01442.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Histone PF00125.19 OAJ01443.1 - 5.7e-09 35.9 0.0 1.4e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SR-25 PF10500.4 OAJ01469.1 - 0.0017 17.8 15.8 0.0017 17.8 10.9 3.0 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein FancD2 PF14631.1 OAJ01469.1 - 7.7 3.4 7.0 12 2.8 4.9 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease TPR_12 PF13424.1 OAJ01535.1 - 2.4e-10 40.1 12.2 0.0004 20.2 0.4 4.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ01535.1 - 8.7e-06 25.5 14.8 0.013 15.4 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ01535.1 - 0.0029 17.3 10.8 11 6.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat SLT_2 PF13406.1 OAJ01535.1 - 0.12 11.2 3.2 0.32 9.8 0.0 2.7 4 0 0 4 4 4 0 Transglycosylase SLT domain TPR_6 PF13174.1 OAJ01535.1 - 2.1 8.9 5.4 24 5.6 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat ELFV_dehydrog_N PF02812.13 OAJ01538.1 - 9e-44 148.2 0.0 1.3e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain zf-CCHC_6 PF15288.1 OAJ01540.1 - 0.006 16.2 0.5 0.018 14.6 0.4 1.8 1 0 0 1 1 1 1 Zinc knuckle NPV_P10 PF05531.7 OAJ01586.1 - 0.00029 21.0 0.1 0.0007 19.7 0.1 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein An_peroxidase PF03098.10 OAJ01606.1 - 4.3e-10 38.5 0.0 5.2e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase rRNA_processing PF08524.6 OAJ01645.1 - 9.2e-06 25.5 0.1 9.2e-06 25.5 0.1 3.4 3 1 1 4 4 4 2 rRNA processing SDA1 PF05285.7 OAJ01646.1 - 0.16 11.2 16.1 0.26 10.5 11.2 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 OAJ01646.1 - 0.23 9.4 11.3 0.39 8.7 7.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 OAJ01646.1 - 0.46 8.3 21.4 0.67 7.8 14.8 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 OAJ01646.1 - 0.79 9.2 14.2 1.5 8.3 9.8 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Transposase_21 PF02992.9 OAJ01672.1 - 0.0037 16.3 0.0 0.006 15.6 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 zf-C3HC4 PF00097.20 OAJ01675.1 - 4.2e-06 26.3 0.4 4.2e-06 26.3 0.3 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ01675.1 - 8.4e-06 25.7 2.3 8.4e-06 25.7 1.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ01675.1 - 7.8e-05 22.2 4.9 0.00032 20.2 0.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ01675.1 - 0.00021 21.0 7.8 0.00022 20.9 1.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 OAJ01675.1 - 0.0005 19.7 3.4 0.0027 17.3 0.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 OAJ01675.1 - 0.00095 18.9 3.0 0.0029 17.3 1.2 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 OAJ01675.1 - 0.0015 18.3 2.9 0.0015 18.3 2.0 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 OAJ01675.1 - 0.0088 15.7 2.0 0.0088 15.7 1.4 2.1 2 0 0 2 2 2 1 RING-type zinc-finger ATP-synt_ab_N PF02874.18 OAJ01675.1 - 0.11 12.7 0.7 10 6.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain FAP PF07174.6 OAJ01675.1 - 6.3 6.0 28.7 2.3 7.4 8.1 2.2 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Rhodanese PF00581.15 OAJ01676.1 - 8.8e-09 35.7 0.0 1.6e-08 34.8 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain Ribonuclease PF00545.15 OAJ01721.1 - 1.2e-10 41.3 1.1 2e-10 40.6 0.7 1.3 1 0 0 1 1 1 1 ribonuclease FHA PF00498.21 OAJ01721.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 FHA domain FLILHELTA PF10306.4 OAJ01767.1 - 1.5e-13 50.5 0.1 3.4e-13 49.4 0.1 1.7 1 1 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 OAJ01767.1 - 0.0072 16.5 0.3 0.012 15.8 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Chorein_N PF12624.2 OAJ01768.1 - 3.6e-07 29.7 0.0 4.1e-06 26.3 0.0 2.4 1 1 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Helicase_C_2 PF13307.1 OAJ01804.1 - 1.7e-21 76.9 0.0 1.9e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain zf-met2 PF12907.2 OAJ01846.1 - 0.14 12.1 0.8 0.63 10.0 0.1 2.4 3 0 0 3 3 3 0 Zinc-binding Cutinase PF01083.17 OAJ01847.1 - 6.7e-23 81.3 0.0 7.9e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ01847.1 - 1.3e-05 24.8 0.0 1.4e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ01847.1 - 0.002 17.9 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ01847.1 - 0.0026 17.6 0.0 0.0027 17.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 OAJ01847.1 - 0.0055 16.9 0.0 0.0071 16.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.6 OAJ01847.1 - 0.036 13.4 0.0 0.047 13.1 0.0 1.1 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_2 PF02230.11 OAJ01847.1 - 0.097 12.1 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF676 PF05057.9 OAJ01847.1 - 0.15 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) SAP25 PF15476.1 OAJ01896.1 - 0.088 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 Myb_DNA-bind_4 PF13837.1 OAJ01917.1 - 0.022 14.9 0.0 0.041 14.0 0.0 1.6 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain T2SF PF00482.18 OAJ01919.1 - 0.0099 15.7 0.8 0.023 14.6 0.1 1.8 1 1 1 2 2 2 1 Type II secretion system (T2SS), protein F MitMem_reg PF13012.1 OAJ01919.1 - 0.06 13.4 3.8 0.079 13.0 2.6 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF2721 PF11026.3 OAJ01919.1 - 2.7 7.6 4.4 3.2 7.4 2.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) DDE_Tnp_4 PF13359.1 OAJ01920.1 - 4e-20 71.9 0.0 5.8e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 OAJ01920.1 - 0.003 17.1 0.3 0.2 11.1 0.0 2.7 3 0 0 3 3 3 1 Transposase DDE domain UBN2 PF14223.1 OAJ01920.1 - 0.03 14.1 1.2 0.1 12.4 1.1 1.7 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type RNase_H PF00075.19 OAJ01943.1 - 4.4e-09 36.7 0.0 6.7e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAJ01943.1 - 0.016 14.9 0.1 0.032 14.0 0.1 1.6 1 1 0 1 1 1 0 Reverse transcriptase-like AAA PF00004.24 OAJ01944.1 - 6.7e-18 65.1 0.0 3.7e-17 62.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 OAJ01944.1 - 0.00018 21.1 0.0 0.051 13.1 0.0 2.5 2 0 0 2 2 2 2 BCS1 N terminal AAA_22 PF13401.1 OAJ01944.1 - 0.093 12.8 0.0 0.48 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 OAJ01944.1 - 0.11 11.9 0.0 0.37 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF3157 PF11355.3 OAJ01997.1 - 7.1 5.8 7.0 13 4.9 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) E1-E2_ATPase PF00122.15 OAJ02045.1 - 4.6e-64 215.6 5.1 1.4e-63 214.0 2.7 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAJ02045.1 - 5.4e-49 166.1 4.2 1.1e-47 161.8 1.1 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ02045.1 - 1.2e-32 114.0 0.1 8.1e-32 111.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAJ02045.1 - 1.2e-20 72.7 0.0 3.5e-20 71.2 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 OAJ02045.1 - 5.5e-18 64.6 0.0 1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 OAJ02045.1 - 8.6e-15 55.4 0.5 2.2e-14 54.0 0.4 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ02045.1 - 2.7e-06 27.1 0.9 5.9e-05 22.7 0.5 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 OAJ02045.1 - 0.047 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase US22 PF02393.11 OAJ02045.1 - 0.1 12.6 0.0 0.49 10.4 0.0 2.2 2 0 0 2 2 2 0 US22 like SH3_9 PF14604.1 OAJ02077.1 - 1.3e-07 31.0 0.0 2.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ02077.1 - 3e-06 26.5 0.0 6.2e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain TMEM51 PF15345.1 OAJ02077.1 - 0.0055 16.4 0.2 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 Transmembrane protein 51 gpUL132 PF11359.3 OAJ02077.1 - 0.041 13.2 0.1 0.041 13.2 0.1 2.2 2 0 0 2 2 2 0 Glycoprotein UL132 APG12 PF04110.8 OAJ02103.1 - 5.7e-32 109.7 0.0 7.2e-32 109.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 OAJ02103.1 - 0.004 17.1 0.0 0.0047 16.8 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like FliP PF00813.15 OAJ02103.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 FliP family Ran_BP1 PF00638.13 OAJ02104.1 - 4.3e-51 172.0 2.0 7.3e-51 171.3 1.4 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 OAJ02104.1 - 4.5e-06 26.3 1.0 2.5e-05 23.9 0.7 1.9 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.9 OAJ02104.1 - 0.0002 20.9 0.7 0.00026 20.5 0.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) FctA PF12892.2 OAJ02104.1 - 0.27 12.0 4.9 0.32 11.8 0.2 2.9 2 1 1 3 3 3 0 T surface-antigen of pili ASFV_J13L PF05568.6 OAJ02104.1 - 0.91 9.0 5.1 1.4 8.4 3.5 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein BTB_2 PF02214.17 OAJ02129.1 - 0.02 15.1 0.0 0.52 10.5 0.0 2.6 2 1 0 2 2 2 0 BTB/POZ domain FAM177 PF14774.1 OAJ02129.1 - 0.046 13.6 0.2 7.2 6.5 0.0 2.2 2 0 0 2 2 2 0 FAM177 family Nucleoplasmin PF03066.10 OAJ02129.1 - 0.18 11.3 3.3 6.8 6.1 0.1 2.3 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 OAJ02129.1 - 1.2 9.4 7.7 7.7 6.8 0.5 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Na_Ca_ex PF01699.19 OAJ02130.1 - 9.1e-24 83.6 22.5 2e-18 66.3 8.6 3.1 3 1 0 3 3 3 2 Sodium/calcium exchanger protein DUF872 PF05915.7 OAJ02130.1 - 0.61 9.9 3.0 0.57 10.0 0.4 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) PIF1 PF05970.9 OAJ02155.1 - 5.8e-24 84.7 0.0 2e-23 82.9 0.0 1.7 1 1 0 1 1 1 1 PIF1-like helicase Dimer_Tnp_hAT PF05699.9 OAJ02156.1 - 5.6e-11 41.9 0.0 9.1e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ESR1_C PF12743.2 OAJ02156.1 - 0.13 11.7 0.1 0.36 10.4 0.1 1.7 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal BRX PF08381.6 OAJ02156.1 - 1.6 7.8 4.3 4.9 6.3 3.0 1.8 1 1 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 FHA PF00498.21 OAJ02186.1 - 0.014 15.4 0.1 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 FHA domain Tim17 PF02466.14 OAJ02220.1 - 7.6e-37 126.2 4.3 1.1e-36 125.7 3.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 OAJ02220.1 - 0.07 13.0 0.6 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) DUF4117 PF13491.1 OAJ02220.1 - 0.12 11.8 1.5 0.94 8.9 1.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4117) RRM_1 PF00076.17 OAJ02221.1 - 1.2e-18 66.5 0.0 2.2e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ02221.1 - 8.5e-12 44.8 0.0 1.4e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ02221.1 - 1.8e-09 37.2 0.0 2.9e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAJ02221.1 - 0.0053 16.4 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Mpv17_PMP22 PF04117.7 OAJ02222.1 - 8e-09 35.0 0.8 9.9e-08 31.5 0.6 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family Sigma70_r1_2 PF00140.15 OAJ02222.1 - 0.12 12.0 0.2 0.44 10.2 0.1 1.9 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 CaM_bdg_C0 PF10562.4 OAJ02222.1 - 0.16 11.8 0.5 0.28 11.0 0.4 1.4 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit rve PF00665.21 OAJ02250.1 - 1.1e-05 25.5 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ02251.1 - 9.1e-19 67.6 0.0 1.6e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ02251.1 - 1.4e-06 28.7 0.0 4.1e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ02251.1 - 0.0002 21.1 0.1 0.00079 19.1 0.1 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ02251.1 - 0.18 11.7 0.0 0.5 10.3 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease ATP-synt_ab_C PF00306.22 OAJ02254.1 - 0.51 10.8 8.3 0.98 9.9 5.8 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain TFIIA PF03153.8 OAJ02254.1 - 8.8 6.1 17.6 2.1 8.1 8.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Dynamin_M PF01031.15 OAJ02288.1 - 1.5e-113 378.4 0.0 2.3e-113 377.8 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 OAJ02288.1 - 8.9e-56 188.3 0.0 1.6e-55 187.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 OAJ02288.1 - 3.3e-28 97.4 0.2 2.3e-27 94.6 0.1 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 OAJ02288.1 - 0.0021 18.0 0.0 0.0064 16.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAJ02288.1 - 0.042 14.3 0.0 0.09 13.2 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Retrotrans_gag PF03732.12 OAJ02318.1 - 0.0029 17.6 2.2 0.0031 17.5 0.4 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 OAJ02319.1 - 5.5e-05 23.5 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ02319.1 - 0.0035 17.2 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ02319.1 - 0.023 14.5 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease 2OG-FeII_Oxy_3 PF13640.1 OAJ02343.1 - 2.1e-05 24.9 0.1 4.3e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ02343.1 - 0.00019 21.6 0.0 0.00042 20.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PIF1 PF05970.9 OAJ02372.1 - 5.2e-19 68.4 0.0 5.8e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ02372.1 - 4.9e-06 26.2 0.0 6.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ02372.1 - 0.00013 21.6 0.7 0.00019 21.1 0.0 1.6 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 OAJ02372.1 - 0.013 15.3 0.1 0.047 13.5 0.0 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 OAJ02372.1 - 0.019 14.5 0.0 0.037 13.5 0.0 1.5 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 OAJ02372.1 - 0.025 14.2 0.2 0.073 12.7 0.1 1.6 1 1 1 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.4 OAJ02372.1 - 0.048 12.2 0.1 0.065 11.8 0.1 1.3 1 1 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain FliL PF03748.9 OAJ02372.1 - 0.049 13.6 0.0 0.89 9.5 0.0 2.0 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL Arch_ATPase PF01637.13 OAJ02372.1 - 0.056 13.1 0.0 0.075 12.7 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 OAJ02372.1 - 0.066 12.9 0.1 0.52 10.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 OAJ02372.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain IMS_HHH PF11798.3 OAJ02373.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 IMS family HHH motif Band_7 PF01145.20 OAJ02393.1 - 3.1e-24 85.8 4.4 3.8e-24 85.5 1.7 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family Vma12 PF11712.3 OAJ02394.1 - 3.1e-27 95.0 0.0 4.9e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase TFIIIC_sub6 PF10419.4 OAJ02394.1 - 3.3e-09 36.0 0.0 6e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit DUF1772 PF08592.6 OAJ02394.1 - 0.0027 17.4 2.1 0.0077 15.9 1.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) PA_decarbox PF05870.6 OAJ02394.1 - 0.095 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) ALAD PF00490.16 OAJ02396.1 - 1.7e-116 388.6 0.0 1.9e-116 388.5 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase MPC PF03650.8 OAJ02397.1 - 1.1e-38 131.8 0.2 1.3e-38 131.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Pex19 PF04614.7 OAJ02398.1 - 1.9e-54 184.8 3.8 5.4e-54 183.4 2.6 1.7 1 1 0 1 1 1 1 Pex19 protein family DUF1018 PF06252.7 OAJ02398.1 - 0.056 13.9 0.0 21 5.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1018) Sigma70_ner PF04546.8 OAJ02398.1 - 1.3 8.6 11.1 1.3 8.6 4.3 2.4 3 0 0 3 3 3 0 Sigma-70, non-essential region RVT_1 PF00078.22 OAJ02426.1 - 2e-18 66.5 0.0 4.2e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ02426.1 - 7.3e-14 51.9 0.0 1.5e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain KfrA_N PF11740.3 OAJ02426.1 - 1 9.8 7.9 4.1 7.8 0.4 2.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term BUD22 PF09073.5 OAJ02457.1 - 1.6 7.7 12.6 1.7 7.5 8.7 1.0 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.9 OAJ02457.1 - 2 7.8 8.4 2.6 7.5 5.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ribosomal_60s PF00428.14 OAJ02457.1 - 2.9 8.3 10.0 26 5.2 0.0 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Daxx PF03344.10 OAJ02457.1 - 3 6.2 12.2 3.1 6.1 8.5 1.0 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 OAJ02457.1 - 7.4 4.3 13.9 8.2 4.2 9.6 1.0 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.6 OAJ02457.1 - 9.9 5.9 14.1 12 5.6 9.7 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) bZIP_2 PF07716.10 OAJ02483.1 - 0.0069 16.1 6.1 0.0069 16.1 4.2 2.1 2 0 0 2 2 2 1 Basic region leucine zipper GLTSCR1 PF15249.1 OAJ02483.1 - 0.03 14.4 1.5 0.031 14.3 0.1 1.7 2 0 0 2 2 2 0 Glioma tumor suppressor candidate region DUF4092 PF13322.1 OAJ02483.1 - 0.039 13.6 0.3 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4092) NYD-SP28_assoc PF14775.1 OAJ02483.1 - 0.055 13.1 3.5 0.11 12.2 2.5 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF3138 PF11336.3 OAJ02483.1 - 1.8 6.6 5.6 2.3 6.2 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Mnd1 PF03962.10 OAJ02483.1 - 5.7 6.5 8.2 0.19 11.3 1.3 1.7 2 0 0 2 2 2 0 Mnd1 family Pkinase PF00069.20 OAJ02510.1 - 4.2e-41 140.8 0.0 5.9e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ02510.1 - 2.7e-26 92.2 0.0 3.7e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ02510.1 - 0.0019 17.9 0.8 0.0042 16.8 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ02510.1 - 0.0033 16.4 0.0 0.034 13.1 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 OAJ02510.1 - 0.084 11.9 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA PF03153.8 OAJ02510.1 - 5.4 6.7 5.8 9 6.0 4.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GCR1_C PF12550.3 OAJ02536.1 - 2.6e-19 68.8 1.3 4.1e-19 68.2 0.9 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes NPV_P10 PF05531.7 OAJ02536.1 - 0.038 14.2 0.8 0.095 12.9 0.6 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein AvrB_AvrC PF05394.6 OAJ02567.1 - 0.08 11.9 1.0 0.093 11.7 0.7 1.0 1 0 0 1 1 1 0 Avirulence protein EB PF01683.13 OAJ02567.1 - 0.09 12.8 6.9 0.13 12.3 4.8 1.3 1 0 0 1 1 1 0 EB module UPF0506 PF11703.3 OAJ02567.1 - 0.23 11.4 2.8 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 UPF0506 Omega-toxin PF06357.6 OAJ02567.1 - 8 6.1 11.0 1.1 8.8 3.4 2.2 1 1 1 2 2 2 0 Omega-atracotoxin Aldo_ket_red PF00248.16 OAJ02568.1 - 1.1e-26 93.2 0.0 1.3e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 OAJ02569.1 - 1.7e-14 53.3 0.0 2.1e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RVT_1 PF00078.22 OAJ02596.1 - 4.6e-18 65.3 0.0 7.4e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 OAJ02596.1 - 0.0057 16.6 0.6 0.012 15.5 0.4 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Macoilin PF09726.4 OAJ02597.1 - 0.64 8.2 11.0 0.69 8.1 7.7 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 OAJ02597.1 - 2.2 7.7 19.7 2.5 7.5 13.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Zn_protease PF05618.6 OAJ02624.1 - 0.025 14.2 0.2 0.03 14.0 0.1 1.1 1 0 0 1 1 1 0 Putative ATP-dependant zinc protease Herpes_ICP4_N PF03584.10 OAJ02624.1 - 0.049 13.1 0.1 0.055 12.9 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region SH3_8 PF13457.1 OAJ02626.1 - 0.00092 19.3 0.2 0.0014 18.7 0.1 1.2 1 0 0 1 1 1 1 SH3-like domain Histone PF00125.19 OAJ02656.1 - 7.9e-28 96.3 0.7 7.8e-27 93.2 0.2 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ02656.1 - 1.5e-05 25.0 0.1 3.1e-05 24.0 0.0 1.5 2 0 0 2 2 2 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAJ02656.1 - 0.0068 16.4 0.4 0.25 11.4 0.0 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 OAJ02656.1 - 0.05 13.3 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF1325 PF07039.6 OAJ02657.1 - 8.3e-10 38.3 0.0 9.2e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 SGF29 tudor-like domain PGM_PMM_I PF02878.11 OAJ02657.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I RVT_1 PF00078.22 OAJ02688.1 - 5.8e-12 45.4 0.3 1.4e-11 44.1 0.2 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3435 PF11917.3 OAJ02710.1 - 0.00067 18.4 0.0 0.00069 18.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) IncA PF04156.9 OAJ02711.1 - 0.46 10.0 6.6 0.86 9.1 4.6 1.5 1 0 0 1 1 1 0 IncA protein RRN3 PF05327.6 OAJ02711.1 - 0.66 8.0 7.7 0.91 7.5 5.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.8 OAJ02711.1 - 2 8.0 14.2 8.8 5.8 9.8 2.0 1 1 0 1 1 1 0 Sigma-70, non-essential region Pkinase PF00069.20 OAJ02772.1 - 3.3e-71 239.4 0.0 4.6e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ02772.1 - 3e-39 134.6 0.0 5e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 OAJ02772.1 - 1.2e-07 31.2 0.1 3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 OAJ02772.1 - 3.9e-05 22.8 0.1 0.00014 20.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ02772.1 - 0.0009 18.2 0.0 0.01 14.7 0.0 2.3 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 OAJ02772.1 - 0.0015 17.9 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 OAJ02772.1 - 0.0036 17.0 0.6 0.033 13.9 0.0 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 OAJ02772.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinesin-relat_1 PF12711.2 OAJ02772.1 - 0.15 12.5 0.5 1.6 9.1 0.0 2.5 3 0 0 3 3 3 0 Kinesin motor V-SNARE_C PF12352.3 OAJ02836.1 - 4.8e-17 61.7 3.9 1.2e-16 60.5 2.7 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 OAJ02836.1 - 0.00066 19.3 0.0 0.0021 17.7 0.0 1.9 1 0 0 1 1 1 1 Sec20 HDV_ag PF01517.13 OAJ02836.1 - 0.009 15.7 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Hepatitis delta virus delta antigen Caudo_TAP PF02413.12 OAJ02836.1 - 0.083 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein PilJ PF13675.1 OAJ02836.1 - 4.1 7.7 10.0 0.21 11.9 0.6 2.7 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term BCDHK_Adom3 PF10436.4 OAJ02837.1 - 3e-36 124.3 0.0 4.3e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 OAJ02837.1 - 1.3e-12 47.3 0.2 1.2e-07 31.3 0.0 3.3 3 0 0 3 3 3 3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAJ02837.1 - 2e-05 24.2 0.0 4.5e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Vac14_Fig4_bd PF11916.3 OAJ02865.1 - 5.5e-74 247.2 7.2 7.4e-74 246.8 3.8 2.0 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 OAJ02865.1 - 2.4e-46 156.0 0.0 2.3e-41 140.0 0.0 4.0 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 OAJ02865.1 - 2.2e-17 61.5 3.4 5.6e-05 22.8 0.0 8.0 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 OAJ02865.1 - 7.8e-10 38.9 4.9 0.26 11.5 0.0 5.7 4 1 1 5 5 5 4 HEAT repeats Cnd1 PF12717.2 OAJ02865.1 - 7.4e-05 22.6 0.9 1.2 8.9 0.0 4.0 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 OAJ02865.1 - 0.00027 20.8 0.5 0.08 12.8 0.1 3.1 4 0 0 4 4 4 1 Parkin co-regulated protein HEAT_EZ PF13513.1 OAJ02865.1 - 0.00032 21.1 9.3 0.059 13.8 0.0 7.0 7 1 1 8 8 8 1 HEAT-like repeat CLASP_N PF12348.3 OAJ02865.1 - 0.0021 17.4 0.2 4.4 6.5 0.0 4.0 3 1 1 4 4 4 1 CLASP N terminal Dopey_N PF04118.9 OAJ02865.1 - 0.066 11.9 0.3 1.3 7.7 0.0 2.7 2 1 1 3 3 3 0 Dopey, N-terminal Adaptin_N PF01602.15 OAJ02865.1 - 0.54 8.5 2.8 12 4.0 0.4 2.8 2 1 1 3 3 3 0 Adaptin N terminal region Arm PF00514.18 OAJ02865.1 - 0.75 9.7 5.6 6.8 6.6 0.0 5.2 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Gelsolin PF00626.17 OAJ02868.1 - 1.7e-38 130.1 0.0 7.4e-15 54.4 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat DUF4243 PF14027.1 OAJ02869.1 - 7.9e-69 232.6 4.0 1.1e-68 232.1 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Glyco_hydro_47 PF01532.15 OAJ02898.1 - 9.3e-143 476.1 0.0 1.1e-142 475.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 WD40 PF00400.27 OAJ02933.1 - 3.1e-42 140.9 16.9 4.4e-08 32.7 0.3 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 OAJ02933.1 - 1.9e-10 40.3 0.3 1.9e-10 40.3 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ02933.1 - 0.00011 21.7 0.1 0.00026 20.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.1 OAJ02933.1 - 0.062 13.5 1.5 50 4.3 0.0 4.6 4 0 0 4 4 4 0 PQQ-like domain TruD PF01142.13 OAJ02956.1 - 4.7e-41 140.7 0.1 9.1e-30 103.5 0.0 6.3 5 2 0 5 5 5 3 tRNA pseudouridine synthase D (TruD) Peptidase_M23 PF01551.17 OAJ02986.1 - 0.00016 21.6 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M23 EamA PF00892.15 OAJ03016.1 - 0.015 15.3 12.5 0.015 15.3 8.7 1.9 2 0 0 2 2 2 0 EamA-like transporter family TPT PF03151.11 OAJ03016.1 - 0.035 13.7 10.4 0.066 12.8 7.2 1.4 1 0 0 1 1 1 0 Triose-phosphate Transporter family AMP-binding PF00501.23 OAJ03017.1 - 9.5e-72 241.6 0.1 1.2e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ03017.1 - 1.2e-21 77.3 1.9 9.2e-21 74.5 0.1 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain UCH_1 PF13423.1 OAJ03049.1 - 6.2e-36 124.3 0.0 1.2e-35 123.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 OAJ03049.1 - 3.5e-21 76.1 0.0 6.1e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 OAJ03049.1 - 0.00063 18.9 0.0 0.27 10.3 0.0 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PH PF00169.24 OAJ03074.1 - 5.8e-07 29.6 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 PH domain Nucleoplasmin PF03066.10 OAJ03074.1 - 0.33 10.4 6.4 3.2 7.2 5.6 1.7 2 0 0 2 2 2 0 Nucleoplasmin Paf1 PF03985.8 OAJ03074.1 - 0.34 9.5 7.1 0.64 8.7 4.9 1.3 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.7 OAJ03074.1 - 1.1 7.0 9.6 2.4 5.9 6.6 1.5 1 0 0 1 1 1 0 Nop14-like family CAF1A PF12253.3 OAJ03074.1 - 1.2 9.2 8.8 3 8.0 5.4 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A CH PF00307.26 OAJ03111.1 - 1.1e-66 221.6 0.0 1.6e-17 63.5 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 OAJ03111.1 - 2.3e-06 27.1 0.0 1.4 8.6 0.0 4.1 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_7 PF13499.1 OAJ03111.1 - 0.0018 18.4 0.9 0.005 16.9 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 OAJ03111.1 - 0.036 13.3 1.3 0.65 9.4 0.0 3.2 3 0 0 3 3 3 0 EF hand Band_7 PF01145.20 OAJ03112.1 - 6.8e-09 35.8 1.1 1e-08 35.3 0.8 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family PTS_2-RNA PF01885.11 OAJ03112.1 - 0.049 12.9 0.2 0.07 12.4 0.1 1.1 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family Peptidase_S8 PF00082.17 OAJ03114.1 - 1.6e-41 142.3 8.8 1.8e-40 138.8 6.1 2.2 1 1 0 1 1 1 1 Subtilase family PA PF02225.17 OAJ03114.1 - 0.0033 17.0 0.1 0.0089 15.7 0.0 1.7 1 0 0 1 1 1 1 PA domain RVT_1 PF00078.22 OAJ03150.1 - 5.4e-19 68.3 0.0 8.2e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UEV PF05743.8 OAJ03190.1 - 5e-39 132.7 0.1 7.7e-39 132.1 0.1 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 OAJ03190.1 - 1.7e-23 82.0 0.3 3.2e-23 81.0 0.2 1.5 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 OAJ03190.1 - 4e-05 23.0 0.0 0.00011 21.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IncA PF04156.9 OAJ03190.1 - 0.0096 15.5 0.0 0.0096 15.5 0.0 2.2 2 0 0 2 2 2 1 IncA protein DUF788 PF05620.6 OAJ03191.1 - 4.4e-36 124.2 0.4 5.7e-36 123.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Ribosomal_60s PF00428.14 OAJ03191.1 - 0.35 11.2 5.7 0.083 13.2 1.2 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_S28e PF01200.13 OAJ03192.1 - 9.7e-32 108.5 1.0 1e-31 108.4 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e ATP-synt_ab PF00006.20 OAJ03221.1 - 1.2e-109 364.8 0.0 1.8e-109 364.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 OAJ03221.1 - 8.1e-21 74.6 0.2 1.7e-20 73.5 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 OAJ03221.1 - 1.1e-13 51.1 3.8 2.8e-13 49.8 2.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 OAJ03221.1 - 0.041 13.7 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATG16 PF08614.6 OAJ03222.1 - 1.4e-45 155.5 23.5 3.4e-45 154.2 16.3 1.6 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) COMPASS-Shg1 PF05205.7 OAJ03222.1 - 0.034 14.4 3.0 0.67 10.2 2.5 2.2 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 ISG65-75 PF11727.3 OAJ03222.1 - 0.05 12.6 2.3 0.083 11.9 1.6 1.5 1 0 0 1 1 1 0 Invariant surface glycoprotein Mer2 PF09074.5 OAJ03222.1 - 0.063 13.2 7.6 0.13 12.1 5.3 1.5 1 0 0 1 1 1 0 Mer2 ORF6N PF10543.4 OAJ03222.1 - 0.068 13.2 2.0 0.2 11.7 0.4 2.3 2 1 1 3 3 3 0 ORF6N domain LURAP PF14854.1 OAJ03222.1 - 0.074 12.7 2.4 0.11 12.2 0.1 2.4 1 1 1 3 3 3 0 Leucine rich adaptor protein Herpes_capsid PF06112.6 OAJ03222.1 - 0.32 11.0 5.0 0.18 11.8 1.4 2.0 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein RAP1 PF07218.6 OAJ03222.1 - 0.42 8.6 3.1 0.23 9.5 0.9 1.4 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FlgN PF05130.7 OAJ03222.1 - 0.58 10.4 23.6 0.19 11.9 12.0 2.4 1 1 1 2 2 2 0 FlgN protein Fib_alpha PF08702.5 OAJ03222.1 - 3 7.9 12.4 0.14 12.2 4.0 2.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family HsbA PF12296.3 OAJ03255.1 - 0.031 14.1 1.1 0.37 10.6 0.3 2.3 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.7 OAJ03255.1 - 0.034 13.9 1.5 0.88 9.3 0.6 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.6 OAJ03255.1 - 0.037 14.0 0.2 0.96 9.4 0.2 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) RNase_P_pop3 PF08228.6 OAJ03255.1 - 0.12 12.1 0.2 0.28 11.0 0.1 1.6 1 1 0 1 1 1 0 RNase P subunit Pop3 YbjQ_1 PF01906.12 OAJ03255.1 - 0.14 12.5 1.0 9 6.7 0.1 2.9 2 1 2 4 4 4 0 Putative heavy-metal-binding FAD_binding_4 PF01565.18 OAJ03295.1 - 1.5e-27 95.7 1.6 2.8e-27 94.8 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAJ03295.1 - 1.7e-06 27.8 0.1 3.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF3357 PF11837.3 OAJ03295.1 - 0.032 14.0 0.5 0.075 12.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) NLBH PF05211.7 OAJ03295.1 - 0.23 10.6 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) K_channel_TID PF07941.6 OAJ03336.1 - 0.0095 16.1 7.6 0.0095 16.1 5.3 3.7 2 1 3 5 5 5 1 Potassium channel Kv1.4 tandem inactivation domain Nucleoplasmin PF03066.10 OAJ03336.1 - 0.38 10.2 5.8 0.15 11.5 2.0 1.8 2 0 0 2 2 2 0 Nucleoplasmin DUF1387 PF07139.6 OAJ03336.1 - 0.67 9.4 10.7 0.12 11.9 4.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) zf-DHHC PF01529.15 OAJ03337.1 - 1.3e-39 135.3 0.5 2.3e-39 134.5 0.3 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Arc_PepC_II PF06847.6 OAJ03337.1 - 2.7 8.4 5.6 0.4 11.1 0.8 1.9 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II tRNA_int_end_N2 PF12928.2 OAJ03370.1 - 8.8e-05 21.8 0.0 0.0002 20.7 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 OAJ03370.1 - 0.00029 20.3 0.0 0.00061 19.2 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain TFIIF_alpha PF05793.7 OAJ03371.1 - 0.19 10.0 11.0 0.28 9.5 7.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 OAJ03371.1 - 0.2 10.1 8.7 0.31 9.4 6.0 1.2 1 0 0 1 1 1 0 Daxx Family PBP_sp32 PF07222.7 OAJ03371.1 - 0.29 10.2 3.1 0.56 9.3 2.2 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 NARP1 PF12569.3 OAJ03371.1 - 2.5 6.7 7.4 3.8 6.1 5.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Myb_DNA-bind_3 PF12776.2 OAJ03405.1 - 2.1e-05 25.0 0.6 4.2e-05 24.1 0.1 1.7 2 0 0 2 2 1 1 Myb/SANT-like DNA-binding domain Trypan_PARP PF05887.6 OAJ03405.1 - 0.008 16.0 5.0 0.014 15.2 3.5 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Myc_N PF01056.13 OAJ03405.1 - 0.02 14.1 4.0 0.025 13.7 2.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 OAJ03405.1 - 0.24 11.6 6.4 0.41 10.9 4.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 OAJ03405.1 - 0.25 10.8 4.2 0.33 10.4 2.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin FLO_LFY PF01698.11 OAJ03405.1 - 0.31 9.8 1.7 0.36 9.6 1.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein NOA36 PF06524.7 OAJ03405.1 - 0.33 10.1 3.4 0.42 9.8 2.3 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 OAJ03405.1 - 0.34 8.9 3.0 0.32 8.9 2.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 OAJ03405.1 - 0.35 11.2 6.8 0.83 9.9 4.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Atrophin-1 PF03154.10 OAJ03405.1 - 0.48 8.4 4.4 0.56 8.2 3.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF4611 PF15387.1 OAJ03405.1 - 0.71 10.0 9.6 0.27 11.3 4.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) TT_ORF2 PF02957.10 OAJ03405.1 - 9.4 6.9 8.2 2.8 8.6 3.6 1.7 2 0 0 2 2 2 0 TT viral ORF2 RVT_2 PF07727.9 OAJ03408.1 - 2.7e-88 295.0 0.0 3.7e-88 294.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ03410.1 - 1.8e-06 28.0 0.0 4.7e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ03410.1 - 0.00038 20.0 0.1 0.0008 18.9 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain DPBB_1 PF03330.13 OAJ03443.1 - 1.1e-05 25.3 1.3 0.00014 21.7 0.6 2.8 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ03443.1 - 1.6e-05 24.5 0.3 0.13 11.9 0.1 2.4 2 0 0 2 2 2 2 Barwin family FAM220 PF15487.1 OAJ03479.1 - 0.95 8.7 6.4 2.2 7.6 4.4 1.5 1 0 0 1 1 1 0 FAM220 family SR-25 PF10500.4 OAJ03479.1 - 5.9 6.2 13.5 11 5.3 9.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ets PF00178.17 OAJ03480.1 - 0.078 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Ets-domain HEAT PF02985.17 OAJ03482.1 - 4.7e-06 26.2 1.4 0.88 9.8 0.0 5.1 6 0 0 6 6 6 2 HEAT repeat Pkinase PF00069.20 OAJ03482.1 - 0.046 12.8 0.0 0.13 11.3 0.0 1.6 1 1 0 1 1 1 0 Protein kinase domain HEAT_EZ PF13513.1 OAJ03482.1 - 0.066 13.7 0.1 0.066 13.7 0.1 3.8 5 0 0 5 5 5 0 HEAT-like repeat AA_permease_2 PF13520.1 OAJ03518.1 - 1.5e-08 33.5 13.2 8.6e-07 27.8 8.8 2.1 1 1 1 2 2 2 2 Amino acid permease RVT_3 PF13456.1 OAJ03561.1 - 0.025 14.3 0.1 0.41 10.4 0.0 2.6 3 0 0 3 3 3 0 Reverse transcriptase-like MotB_plug PF13677.1 OAJ03561.1 - 0.032 13.5 0.1 2.3 7.6 0.0 2.7 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB RVT_1 PF00078.22 OAJ03561.1 - 0.077 12.3 0.0 0.25 10.6 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 OAJ03562.1 - 0.019 14.8 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 OAJ03562.1 - 0.024 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease BRF1 PF07741.8 OAJ03562.1 - 0.032 14.4 2.5 0.14 12.3 1.0 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain zf-CCHC PF00098.18 OAJ03562.1 - 0.078 12.9 1.8 0.16 11.9 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ03562.1 - 0.49 10.1 1.6 1.1 8.9 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 OAJ03605.1 - 1.7e-19 70.0 0.0 2.9e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ03605.1 - 3.1e-15 56.3 0.0 9.6e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ03605.1 - 0.00017 21.9 0.0 0.00046 20.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ03605.1 - 0.0052 16.6 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ03605.1 - 0.011 15.5 0.1 0.028 14.2 0.1 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease dUTPase PF00692.14 OAJ03605.1 - 0.19 11.1 0.0 0.4 10.1 0.0 1.4 1 0 0 1 1 1 0 dUTPase Senescence PF06911.7 OAJ03642.1 - 1.3e-28 99.9 0.5 2.2e-28 99.1 0.3 1.4 1 0 0 1 1 1 1 Senescence-associated protein Gar1 PF04410.9 OAJ03681.1 - 2.4e-23 82.2 11.7 4.4e-14 52.2 0.1 3.9 4 0 0 4 4 4 2 Gar1/Naf1 RNA binding region FoP_duplication PF13865.1 OAJ03682.1 - 5.1e-07 30.0 0.2 8.3e-07 29.3 0.2 1.4 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Neisseria_TspB PF05616.8 OAJ03682.1 - 0.3 9.4 1.6 0.3 9.4 1.1 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF1014 PF06244.7 OAJ03761.1 - 2.2e-20 73.0 26.9 1.2e-18 67.4 18.6 3.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) DUF4551 PF15087.1 OAJ03761.1 - 3.4 5.9 10.1 4.2 5.6 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Cript PF10235.4 OAJ03762.1 - 3.6e-24 84.9 0.9 3.6e-24 84.9 0.6 1.7 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT zinc_ribbon_2 PF13240.1 OAJ03762.1 - 0.036 13.5 1.7 0.036 13.5 1.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain C6_DPF PF10170.4 OAJ03762.1 - 0.12 12.4 5.5 0.3 11.1 2.0 2.2 2 1 0 2 2 2 0 Cysteine-rich domain Herpes_capsid PF06112.6 OAJ03762.1 - 0.25 11.3 4.1 0.28 11.2 2.8 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF2039 PF10217.4 OAJ03762.1 - 0.44 10.5 12.7 0.12 12.3 4.8 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-ribbon_3 PF13248.1 OAJ03762.1 - 1.5 8.1 12.5 0.34 10.1 0.7 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Phage_integrase PF00589.17 OAJ03799.1 - 0.011 15.3 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Phage integrase family Phage_int_SAM_1 PF02899.12 OAJ03799.1 - 0.096 12.8 0.0 0.49 10.5 0.0 2.2 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain RVT_1 PF00078.22 OAJ03834.1 - 2.7e-16 59.5 0.0 5.5e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ03834.1 - 3.8e-14 52.8 0.0 9.7e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ03834.1 - 0.0003 21.2 0.0 0.0009 19.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ03834.1 - 0.0043 16.9 0.0 0.0092 15.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.21 OAJ03872.1 - 4.5e-14 52.5 0.0 9.1e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ03872.1 - 9.9e-05 21.7 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ03873.1 - 0.0024 18.3 0.0 0.0066 16.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ03873.1 - 0.051 13.3 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ03873.1 - 0.11 12.4 0.0 0.55 10.1 0.0 2.0 1 1 0 1 1 1 0 Retroviral aspartyl protease Transposase_21 PF02992.9 OAJ03918.1 - 4.6e-17 61.8 0.0 1e-16 60.7 0.0 1.4 2 0 0 2 2 2 1 Transposase family tnp2 Leucyl-specific PF14795.1 OAJ03918.1 - 0.11 12.3 0.1 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain Arylsulfotran_2 PF14269.1 OAJ03953.1 - 1.8e-36 125.8 0.0 4.9e-36 124.4 0.0 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 OAJ03953.1 - 7.3e-09 34.6 2.9 1.4e-08 33.7 2.0 1.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) LRR_4 PF12799.2 OAJ03954.1 - 1.3e-30 104.4 12.7 3.3e-08 32.9 0.5 5.7 4 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ03954.1 - 8.5e-20 70.2 22.6 8.5e-07 28.6 1.6 4.7 2 1 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 OAJ03954.1 - 2.2e-15 54.2 13.1 0.5 10.5 0.0 8.4 7 2 0 7 7 7 6 Leucine Rich Repeat LRR_6 PF13516.1 OAJ03954.1 - 1.8e-12 45.9 11.3 0.09 12.8 0.0 8.1 6 2 1 7 7 7 3 Leucine Rich repeat LRR_7 PF13504.1 OAJ03954.1 - 7.7e-12 43.3 7.5 0.95 9.9 0.0 8.2 9 0 0 9 9 9 3 Leucine rich repeat LRR_9 PF14580.1 OAJ03954.1 - 9.8e-11 41.5 2.2 0.0012 18.4 0.0 3.6 1 1 2 3 3 3 3 Leucine-rich repeat NPHI_C PF08469.5 OAJ03954.1 - 0.024 14.5 0.1 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal RVT_1 PF00078.22 OAJ04024.1 - 4.3e-18 65.4 0.0 9.1e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 OAJ04054.1 - 0.72 9.9 3.7 0.51 10.4 0.2 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein GRP PF07172.6 OAJ04054.1 - 1.4 9.4 29.2 2.3 8.7 20.3 1.3 1 0 0 1 1 1 0 Glycine rich protein family DUF566 PF04484.7 OAJ04055.1 - 1.9 7.9 13.3 2 7.8 9.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) TFIIF_alpha PF05793.7 OAJ04091.1 - 2.9 6.1 38.5 9.2 4.4 26.7 1.8 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.5 OAJ04091.1 - 9.8 5.1 34.4 31 3.4 23.8 1.8 1 0 0 1 1 1 0 BUD22 Transposase_21 PF02992.9 OAJ04093.1 - 5.8e-20 71.3 0.0 9.9e-20 70.5 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 CPSase_L_chain PF00289.17 OAJ04134.1 - 6.1e-05 23.0 0.0 7.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Abhydrolase_8 PF06259.7 OAJ04134.1 - 0.0055 16.2 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 2 Alpha/beta hydrolase Peptidase_M17_N PF02789.12 OAJ04134.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Ribosomal_L7Ae PF01248.21 OAJ04170.1 - 5.4e-28 96.3 1.8 6.8e-28 96.0 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1353 PF07087.6 OAJ04170.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) DUF2042 PF09743.4 OAJ04170.1 - 0.15 11.3 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2042) Ribosomal_S17 PF00366.15 OAJ04171.1 - 6.6e-31 106.1 0.7 1e-30 105.5 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 RVT_1 PF00078.22 OAJ04204.1 - 8.8e-16 57.9 0.0 1.6e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ04204.1 - 0.0053 17.2 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease SWIM PF04434.12 OAJ04207.1 - 6.6e-08 31.8 0.1 1.3e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger MULE PF10551.4 OAJ04207.1 - 1.1e-07 31.9 0.0 2.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Collagen PF01391.13 OAJ04245.1 - 3.8e-15 55.1 60.5 2.1e-09 36.7 19.7 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) TPR_12 PF13424.1 OAJ04281.1 - 1.3e-36 124.3 60.0 8.5e-08 32.0 0.2 10.3 3 3 8 13 13 13 12 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ04281.1 - 1e-23 82.5 56.7 0.022 14.6 0.4 15.7 16 0 0 16 16 16 11 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ04281.1 - 1.6e-09 36.9 29.6 2.5 8.2 0.1 12.9 15 0 0 15 15 15 4 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ04281.1 - 2.4e-05 23.7 9.5 13 5.6 0.0 9.1 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ04281.1 - 0.0011 18.5 36.3 1.1 8.9 0.6 9.5 5 2 5 10 10 10 7 TPR repeat DUF4206 PF13901.1 OAJ04281.1 - 0.0069 15.9 1.1 20 4.6 0.0 4.5 4 1 0 4 4 4 0 Domain of unknown function (DUF4206) Ssu72 PF04722.8 OAJ04281.1 - 0.016 14.5 0.2 24 4.1 0.0 5.0 3 2 0 4 4 4 0 Ssu72-like protein TPR_16 PF13432.1 OAJ04281.1 - 0.96 10.1 37.7 0.032 14.9 1.4 8.8 7 3 2 10 10 10 0 Tetratricopeptide repeat Prefoldin_2 PF01920.15 OAJ04281.1 - 1.3 8.7 8.9 29 4.4 0.1 5.5 6 0 0 6 6 6 0 Prefoldin subunit FA_hydroxylase PF04116.8 OAJ04323.1 - 1.1e-12 48.3 9.6 1.1e-12 48.3 6.6 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RVT_1 PF00078.22 OAJ04325.1 - 4.1e-08 32.8 0.0 4.7e-08 32.6 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3762 PF12591.3 OAJ04325.1 - 0.048 13.6 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) rve PF00665.21 OAJ04326.1 - 4.7e-19 68.6 0.0 9.2e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ04326.1 - 0.0014 18.1 0.0 0.0034 16.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain AIPR PF10592.4 OAJ04326.1 - 0.1 11.8 0.1 4.7 6.4 0.1 2.1 2 0 0 2 2 2 0 AIPR protein PHBC_N PF12551.3 OAJ04368.1 - 0.00035 20.0 1.5 0.00044 19.7 1.1 1.2 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase N terminal Peroxidase_2 PF01328.12 OAJ04369.1 - 1.3e-19 69.9 0.1 1.9e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 SseC PF04888.7 OAJ04414.1 - 0.41 9.9 8.0 0.18 11.1 2.3 2.0 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Baculo_PEP_C PF04513.7 OAJ04414.1 - 0.43 10.3 3.8 0.18 11.5 0.8 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RVT_1 PF00078.22 OAJ04496.1 - 9.1e-26 90.5 0.0 1.3e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hist_deacetyl PF00850.14 OAJ04531.1 - 1.5e-65 221.5 1.6 2.8e-65 220.6 1.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain IF-2B PF01008.12 OAJ04562.1 - 5.9e-61 205.9 0.0 8.1e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Sugar_tr PF00083.19 OAJ04563.1 - 5.6e-84 282.3 22.0 6.4e-84 282.1 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ04563.1 - 1.3e-27 96.4 22.8 1.3e-27 96.4 15.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAJ04563.1 - 0.00023 19.4 0.5 0.00047 18.5 0.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4227 PF14004.1 OAJ04563.1 - 1.9 8.4 3.9 21 5.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) MutS_V PF00488.16 OAJ04608.1 - 1.8e-17 63.5 0.6 7e-12 45.2 0.2 2.1 1 1 1 2 2 2 2 MutS domain V MutS_V PF00488.16 OAJ04609.1 - 1.6e-07 30.9 0.2 3.8e-06 26.4 0.1 2.2 1 1 0 1 1 1 1 MutS domain V DUF3416 PF11896.3 OAJ04610.1 - 0.012 15.5 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) Vip3A_N PF12495.3 OAJ04610.1 - 0.023 14.4 0.1 0.026 14.2 0.1 1.2 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Hrs_helical PF12210.3 OAJ04610.1 - 0.088 13.0 1.1 0.12 12.6 0.7 1.3 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF2746 PF10874.3 OAJ04610.1 - 0.19 11.9 5.5 0.14 12.3 2.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2746) MutS_II PF05188.12 OAJ04611.1 - 1.4e-08 34.9 0.1 1.7e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 MutS domain II Mtf2_C PF14061.1 OAJ04653.1 - 0.1 12.5 0.1 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 GAF_3 PF13492.1 OAJ04654.1 - 0.019 15.0 0.0 0.27 11.3 0.0 2.7 2 1 0 2 2 2 0 GAF domain Pex14_N PF04695.8 OAJ04654.1 - 1.7 8.6 8.8 1.3 9.0 4.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ASF1_hist_chap PF04729.8 OAJ04697.1 - 1.2e-10 41.2 0.0 1.2e-10 41.1 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone ICL PF00463.16 OAJ04698.1 - 3.1e-116 388.6 4.2 1e-67 228.5 0.1 3.7 1 1 2 3 3 3 3 Isocitrate lyase family Arg_repressor_C PF02863.13 OAJ04698.1 - 0.051 13.0 0.1 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain RVT_1 PF00078.22 OAJ04742.1 - 1.8e-17 63.3 0.0 3.6e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ04742.1 - 2.5e-12 46.9 0.0 4.7e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ04742.1 - 1e-05 25.9 0.0 2.7e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ04742.1 - 0.0015 18.3 0.0 0.0039 17.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ04742.1 - 0.0052 16.5 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Exo_endo_phos_2 PF14529.1 OAJ04784.1 - 5.5e-12 45.3 0.0 2.2e-11 43.3 0.0 2.0 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ04784.1 - 6.2e-06 26.3 0.4 1.1e-05 25.4 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 OAJ04784.1 - 1.2e-05 24.7 0.0 0.00032 20.1 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ04838.1 - 8.7e-17 61.3 0.0 7e-16 58.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ05011.1 - 2.6e-14 53.1 0.0 5.2e-14 52.1 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ05012.1 - 6.1e-21 74.7 0.1 1.1e-20 73.8 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ05012.1 - 0.00077 18.9 0.0 0.002 17.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain PAS_3 PF08447.6 OAJ05012.1 - 0.054 13.6 0.8 0.18 11.9 0.5 1.9 1 0 0 1 1 1 0 PAS fold Exo_endo_phos PF03372.18 OAJ05016.1 - 3.6e-05 23.8 0.1 5.8e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 OAJ05016.1 - 9.5e-05 22.0 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RRM_1 PF00076.17 OAJ05067.1 - 9e-37 124.5 0.0 1.4e-17 63.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ05067.1 - 4.3e-30 103.4 0.0 2.3e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ05067.1 - 2e-14 53.1 0.0 1.2e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ05067.1 - 0.013 15.3 0.0 4.3 7.2 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif ATP-grasp_2 PF08442.5 OAJ05067.1 - 0.025 13.9 0.0 2.9 7.2 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain Glyco_hydro_30 PF02055.11 OAJ05068.1 - 4.4e-20 71.3 0.8 2.4e-19 68.9 0.5 1.8 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 RVT_1 PF00078.22 OAJ05115.1 - 4.2e-16 58.9 0.0 7.8e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ05115.1 - 1.8e-12 47.4 0.0 6.2e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ05115.1 - 0.00094 19.6 0.0 0.0028 18.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ05115.1 - 0.009 15.9 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ05115.1 - 0.028 14.2 0.1 0.096 12.5 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Sec23_trunk PF04811.10 OAJ05202.1 - 7e-76 254.7 0.0 1e-75 254.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 OAJ05202.1 - 1.2e-34 117.8 0.3 2.1e-34 117.0 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 OAJ05202.1 - 4.1e-31 107.3 0.0 7.6e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 OAJ05202.1 - 1.7e-16 59.4 5.4 3.1e-16 58.6 3.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 OAJ05202.1 - 7.8e-13 47.9 0.0 1.8e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat RF-1 PF00472.15 OAJ05203.1 - 1.9e-13 50.2 0.3 3.4e-13 49.4 0.2 1.4 1 0 0 1 1 1 1 RF-1 domain Gly_rich PF12810.2 OAJ05205.1 - 0.36 10.3 49.1 0.077 12.5 28.6 3.1 1 1 1 2 2 2 0 Glycine rich protein RVT_1 PF00078.22 OAJ05252.1 - 1.9e-11 43.7 0.0 2.8e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PSP1 PF04468.7 OAJ05299.1 - 8.2e-32 109.0 0.1 1.3e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Serinc PF03348.10 OAJ05352.1 - 6e-53 180.0 0.0 8.7e-53 179.5 0.0 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) MMS19_C PF12460.3 OAJ05407.1 - 7.5e-09 34.8 1.7 4.2e-08 32.3 0.3 2.0 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal HEAT PF02985.17 OAJ05407.1 - 0.047 13.7 4.4 0.11 12.6 0.0 3.2 3 1 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.1 OAJ05407.1 - 0.071 13.4 0.6 1.2 9.4 0.1 2.2 2 0 0 2 2 2 0 HEAT repeats DUF4042 PF13251.1 OAJ05407.1 - 0.22 10.9 0.6 1.1 8.6 0.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4042) HEAT_EZ PF13513.1 OAJ05407.1 - 0.26 11.8 3.7 1.4 9.5 0.4 2.6 2 0 0 2 2 2 0 HEAT-like repeat DUF1302 PF06980.6 OAJ05410.1 - 1.6e-117 393.3 9.1 2.4e-117 392.8 6.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1302) DUF1329 PF07044.6 OAJ05411.1 - 1e-125 419.5 4.7 1.2e-125 419.2 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1329) TSC22 PF01166.13 OAJ05457.1 - 0.024 14.5 0.1 0.064 13.2 0.1 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family CDC45 PF02724.9 OAJ05457.1 - 1.3 6.9 15.2 0.15 10.0 7.6 1.6 2 0 0 2 2 2 0 CDC45-like protein YL1 PF05764.8 OAJ05457.1 - 3.1 7.3 22.6 0.3 10.6 12.3 1.6 2 0 0 2 2 2 0 YL1 nuclear protein Asp_protease_2 PF13650.1 OAJ05501.1 - 0.0001 22.7 0.2 0.0003 21.2 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ05501.1 - 0.051 13.4 0.1 0.19 11.5 0.1 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ05501.1 - 0.18 11.7 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Glyco_tranf_2_3 PF13641.1 OAJ05551.1 - 4.4e-26 92.0 0.0 5.8e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 OAJ05551.1 - 8.1e-21 74.6 4.7 8.1e-21 74.6 3.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 OAJ05551.1 - 9.9e-11 41.2 0.0 1.5e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 OAJ05551.1 - 1.3e-06 28.2 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 OAJ05551.1 - 0.064 12.3 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Ribosomal_L29e PF01779.12 OAJ05552.1 - 1.4e-08 34.4 0.6 2.3e-08 33.7 0.4 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family Pkinase PF00069.20 OAJ05586.1 - 7.2e-60 202.3 0.0 5.1e-58 196.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ05586.1 - 9.4e-27 93.7 0.0 1e-25 90.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ05586.1 - 1.4e-05 24.2 0.0 2.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF2155 PF09923.4 OAJ05639.1 - 0.031 14.3 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2155) Cellulase PF00150.13 OAJ05640.1 - 4.6e-06 26.0 0.1 6.5e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Chorein_N PF12624.2 OAJ05695.1 - 5.8e-34 116.1 0.0 1.2e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter adh_short_C2 PF13561.1 OAJ05695.1 - 9.5e-11 41.9 0.0 1.4e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ05695.1 - 5.1e-05 23.2 0.1 9.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ05695.1 - 0.00038 20.1 0.0 0.00067 19.3 0.0 1.4 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.11 OAJ05697.1 - 2.1e-06 26.6 1.3 2.8e-06 26.2 0.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_integrase PF00589.17 OAJ05699.1 - 0.00024 20.8 0.0 0.00039 20.1 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family RVT_3 PF13456.1 OAJ05700.1 - 0.001 18.8 0.1 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like DNA_pol_viral_C PF00336.13 OAJ05700.1 - 0.012 14.8 0.1 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Exo_endo_phos_2 PF14529.1 OAJ05755.1 - 0.051 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase RVT_1 PF00078.22 OAJ05756.1 - 1.2e-12 47.6 0.0 1.5e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Med3 PF11593.3 OAJ05759.1 - 1.1 8.3 8.5 1.2 8.2 5.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SelP_N PF04592.9 OAJ05759.1 - 6.1 6.1 7.8 8.5 5.6 5.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF566 PF04484.7 OAJ05759.1 - 8.1 5.8 10.5 11 5.3 7.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) LIP PF03583.9 OAJ05760.1 - 3.4e-38 131.5 0.0 4.4e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 OAJ05760.1 - 0.001 18.8 0.1 0.0032 17.2 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ05760.1 - 0.0043 16.9 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ05760.1 - 0.13 11.4 0.3 3 6.9 0.0 2.5 2 1 1 3 3 3 0 Prolyl oligopeptidase family RVT_1 PF00078.22 OAJ05814.1 - 2.4e-20 72.7 0.0 4.3e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAJ05814.1 - 1.1e-14 54.8 0.0 2.9e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 OAJ05814.1 - 7.8e-13 48.0 0.1 7.8e-13 48.0 0.1 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase ACPS PF01648.15 OAJ05817.1 - 4.4e-05 23.2 0.0 6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short_C2 PF13561.1 OAJ05817.1 - 0.004 16.9 0.1 0.13 12.0 0.1 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ05817.1 - 0.044 13.7 1.0 0.061 13.2 0.2 1.6 2 0 0 2 2 2 0 short chain dehydrogenase rve PF00665.21 OAJ05867.1 - 2.4e-10 40.5 0.0 5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ05867.1 - 0.088 12.1 0.1 0.22 10.8 0.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Inhibitor_Mig-6 PF11555.3 OAJ05868.1 - 0.026 14.8 3.0 0.05 13.9 2.1 1.4 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 THOC7 PF05615.8 OAJ05930.1 - 7.5e-09 35.9 4.8 7.5e-09 35.9 3.4 2.4 1 1 1 2 2 2 1 Tho complex subunit 7 AAA_13 PF13166.1 OAJ05930.1 - 3.7e-05 22.4 2.8 5.8e-05 21.7 1.9 1.2 1 0 0 1 1 1 1 AAA domain Mnd1 PF03962.10 OAJ05930.1 - 0.00084 19.0 2.2 0.00084 19.0 1.6 2.3 1 1 1 2 2 2 1 Mnd1 family Phlebovirus_NSM PF07246.6 OAJ05930.1 - 0.031 13.4 1.7 0.034 13.3 0.2 1.7 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M ADIP PF11559.3 OAJ05930.1 - 4.1 7.2 11.3 6.7 6.6 2.3 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding zf-CCHC PF00098.18 OAJ05982.1 - 2.6e-06 27.0 2.0 2.6e-06 27.0 1.4 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ05982.1 - 0.0011 18.3 0.4 0.0021 17.4 0.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 OAJ05982.1 - 0.063 12.7 0.5 0.12 11.9 0.4 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.1 OAJ05982.1 - 0.092 12.4 1.4 0.17 11.5 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.21 OAJ05983.1 - 1.8e-20 73.2 0.0 3.1e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ05983.1 - 3.4e-07 29.8 0.2 7e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ05983.1 - 0.00043 19.7 0.5 0.0057 16.1 0.1 2.7 2 1 0 2 2 2 1 Integrase core domain Flt3_lig PF02947.9 OAJ05983.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 flt3 ligand RVT_2 PF07727.9 OAJ05984.1 - 7.8e-86 287.0 0.0 1e-85 286.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAJ05984.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Metallophos PF00149.23 OAJ06096.1 - 6.2e-07 29.0 2.4 4.1e-06 26.3 0.4 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Flavokinase PF01687.12 OAJ06097.1 - 2.7e-35 120.9 0.0 3.9e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase DUF3425 PF11905.3 OAJ06160.1 - 3.4e-10 39.9 0.0 1e-09 38.3 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 OAJ06160.1 - 3.3e-07 30.1 5.7 9e-07 28.7 3.9 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAJ06160.1 - 1.4 8.7 7.4 1.1 9.1 2.3 2.3 2 0 0 2 2 2 0 Basic region leucine zipper ATP_transf PF09830.4 OAJ06163.1 - 0.00014 21.5 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 OAJ06163.1 - 0.013 16.0 0.0 0.041 14.4 0.0 1.8 1 0 0 1 1 1 0 HIT domain TBP PF00352.16 OAJ06164.1 - 8.6e-69 226.9 0.2 1.6e-34 117.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 OAJ06164.1 - 0.00011 22.1 0.0 0.45 10.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) ICL PF00463.16 OAJ06277.1 - 9.7e-19 66.9 0.0 1.1e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Rad9 PF04139.8 OAJ06278.1 - 7.1e-39 133.4 0.0 4e-38 130.9 0.0 2.0 1 1 0 1 1 1 1 Rad9 DUF953 PF06110.6 OAJ06278.1 - 4.2e-17 61.6 0.0 7e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.15 OAJ06278.1 - 0.0048 16.5 0.0 0.04 13.6 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_9 PF14595.1 OAJ06278.1 - 0.16 11.5 0.2 0.33 10.5 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin Glyco_hydro_45 PF02015.11 OAJ06280.1 - 1.7e-48 165.3 4.0 2.1e-48 165.0 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 A_deamin PF02137.13 OAJ06333.1 - 5.8e-17 62.0 0.0 8.8e-17 61.4 0.0 1.2 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain Ribosomal_L3 PF00297.17 OAJ06401.1 - 3.5e-120 400.3 4.9 4.3e-120 400.0 3.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 MCM PF00493.18 OAJ06402.1 - 4.4e-28 98.0 0.0 5.7e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family VWA_2 PF13519.1 OAJ06404.1 - 3.2e-08 33.8 0.1 4.2e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 OAJ06404.1 - 0.0062 16.2 0.2 0.0072 16.0 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 OAJ06404.1 - 0.0095 15.5 0.3 0.011 15.2 0.2 1.0 1 0 0 1 1 1 1 Ssl1-like Chorismate_bind PF00425.13 OAJ06404.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 chorismate binding enzyme STE3 PF02076.10 OAJ06405.1 - 4.4e-91 304.8 9.6 5.6e-91 304.5 6.7 1.0 1 0 0 1 1 1 1 Pheromone A receptor Epiglycanin_C PF14654.1 OAJ06405.1 - 0.12 12.3 0.2 0.3 11.0 0.2 1.7 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Dimer_Tnp_hAT PF05699.9 OAJ06458.1 - 5.9e-15 54.6 0.3 1e-14 53.9 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAJ06458.1 - 1.6e-05 24.8 0.1 4.9e-05 23.2 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4413) DOG1 PF14144.1 OAJ06458.1 - 0.03 14.3 0.2 4.1 7.5 0.0 2.7 2 0 0 2 2 2 0 Seed dormancy control Rep_fac_C PF08542.6 OAJ06458.1 - 0.05 13.6 0.2 0.37 10.7 0.1 2.2 2 0 0 2 2 2 0 Replication factor C C-terminal domain SPRY PF00622.23 OAJ06461.1 - 4e-18 65.6 0.2 6.8e-18 64.9 0.2 1.4 1 0 0 1 1 1 1 SPRY domain SPA PF08616.5 OAJ06461.1 - 0.23 11.1 0.1 0.45 10.2 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis DUF3696 PF12476.3 OAJ06521.1 - 0.094 12.7 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) Pkinase PF00069.20 OAJ06581.1 - 6.4e-69 231.9 0.0 8.2e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ06581.1 - 4.9e-49 166.7 0.0 6.5e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ06581.1 - 8.1e-06 24.9 0.0 5.5e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Apt1 PF10351.4 OAJ06581.1 - 2.9 6.6 8.6 0.42 9.4 3.2 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF4563 PF15124.1 OAJ06582.1 - 0.019 14.5 0.2 2.4 7.6 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4563) DUF4140 PF13600.1 OAJ06582.1 - 1.3 9.5 4.5 3.8 8.0 0.9 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) F-box PF00646.28 OAJ06709.1 - 8.9e-05 22.0 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ06709.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 F-box-like Sp100 PF03172.8 OAJ06710.1 - 0.0074 16.2 0.5 0.26 11.2 0.1 2.3 2 0 0 2 2 2 1 Sp100 domain EHN PF06441.7 OAJ06710.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Epoxide hydrolase N terminus HTH_29 PF13551.1 OAJ06774.1 - 3.3e-05 24.0 0.0 8.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 OAJ06774.1 - 7.6e-05 23.4 2.4 8.4e-05 23.3 0.0 2.3 3 0 0 3 3 3 1 Homeodomain-like domain DDE_3 PF13358.1 OAJ06774.1 - 0.00034 20.3 0.0 0.00074 19.2 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_7 PF02796.10 OAJ06774.1 - 0.027 14.3 0.4 0.15 11.9 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Transposase_mut PF00872.13 OAJ06774.1 - 0.084 11.4 0.1 9.1 4.7 0.0 2.1 2 0 0 2 2 2 0 Transposase, Mutator family DLH PF01738.13 OAJ06777.1 - 1.5e-13 50.5 0.6 2e-13 50.1 0.4 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 OAJ06777.1 - 0.00012 21.9 0.1 0.00017 21.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PMP1_2 PF08114.6 OAJ06778.1 - 0.038 13.4 0.4 0.07 12.6 0.3 1.3 1 0 0 1 1 1 0 ATPase proteolipid family Podoplanin PF05808.6 OAJ06778.1 - 0.092 12.3 21.0 0.5 9.9 14.5 2.2 1 1 0 1 1 1 0 Podoplanin Adeno_E3_CR2 PF02439.10 OAJ06778.1 - 0.3 10.6 3.5 0.54 9.8 2.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TFIIA PF03153.8 OAJ06778.1 - 4 7.2 25.6 0.86 9.4 2.7 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit OAD_gamma PF04277.8 OAJ06778.1 - 4 7.8 0.0 4 7.8 0.0 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Apt1 PF10351.4 OAJ06851.1 - 0.13 11.1 5.0 0.15 10.8 3.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SSP160 PF06933.6 OAJ06851.1 - 0.19 9.6 35.6 0.029 12.3 12.9 3.0 2 1 1 3 3 3 0 Special lobe-specific silk protein SSP160 Med3 PF11593.3 OAJ06851.1 - 0.29 10.3 18.1 0.34 10.0 12.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2146 PF10220.4 OAJ06851.1 - 0.31 8.9 5.0 0.38 8.6 3.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF572 PF04502.8 OAJ06851.1 - 0.4 9.8 6.3 0.5 9.5 4.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SOBP PF15279.1 OAJ06851.1 - 1.8 8.8 8.7 3 8.1 6.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein CytochromB561_N PF09786.4 OAJ06851.1 - 2.3 6.5 9.9 2.7 6.3 6.9 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Hid1 PF12722.2 OAJ06851.1 - 2.6 5.5 5.6 3.4 5.2 3.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF566 PF04484.7 OAJ06851.1 - 6 6.2 19.0 8.3 5.8 13.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Sigma70_ner PF04546.8 OAJ06855.1 - 3.8 7.0 11.2 0.18 11.4 3.2 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Cys_Met_Meta_PP PF01053.15 OAJ06924.1 - 2.9e-53 180.5 0.0 1.8e-45 154.9 0.0 2.3 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 OAJ06924.1 - 0.066 11.9 0.1 0.13 10.9 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-V Aminotran_1_2 PF00155.16 OAJ06924.1 - 0.08 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DUF3975 PF13126.1 OAJ06925.1 - 0.24 11.5 5.2 0.14 12.2 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) DENN PF02141.16 OAJ06985.1 - 2.1e-22 79.7 0.0 3.4e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain DUF3450 PF11932.3 OAJ06985.1 - 0.037 13.2 7.4 0.088 12.0 5.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GAS PF13851.1 OAJ06985.1 - 0.25 10.5 13.8 0.03 13.5 6.2 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FlgM PF04316.8 OAJ06985.1 - 0.3 11.0 4.1 0.25 11.3 0.3 2.6 2 1 0 2 2 2 0 Anti-sigma-28 factor, FlgM Myosin_tail_1 PF01576.14 OAJ06985.1 - 0.32 8.6 18.3 0.022 12.5 8.9 1.6 2 0 0 2 2 2 0 Myosin tail Syntaxin PF00804.20 OAJ06985.1 - 0.7 10.0 11.0 5.1 7.3 0.5 2.7 2 0 0 2 2 2 0 Syntaxin Atg14 PF10186.4 OAJ06985.1 - 0.73 8.7 13.8 0.88 8.4 3.9 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 OAJ06985.1 - 0.76 8.1 7.0 0.36 9.2 1.9 1.9 2 0 0 2 2 2 0 AAA domain OmpH PF03938.9 OAJ06985.1 - 0.78 9.6 11.3 0.17 11.8 4.6 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 OAJ06985.1 - 0.82 8.0 2.5 1.8 6.9 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 OAJ06985.1 - 0.92 8.4 13.4 0.074 12.0 5.2 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 Baculo_PEP_C PF04513.7 OAJ06985.1 - 3.2 7.5 5.5 16 5.2 0.2 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_TATA_bd PF12325.3 OAJ06985.1 - 5.2 6.8 15.8 0.76 9.5 5.4 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Filament PF00038.16 OAJ06985.1 - 6.2 6.1 20.8 0.15 11.4 7.9 2.5 2 1 1 3 3 3 0 Intermediate filament protein DUF1423 PF07227.6 OAJ06985.1 - 7.4 5.1 9.4 13 4.2 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) IncA PF04156.9 OAJ06985.1 - 8.7 5.8 17.9 5.8 6.4 8.9 2.5 2 1 0 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 OAJ06985.1 - 9.8 6.0 19.7 2 8.2 2.0 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Coatomer_WDAD PF04053.9 OAJ07148.1 - 2.3e-129 432.0 0.0 3.8e-98 329.1 0.0 2.5 2 1 1 3 3 3 2 Coatomer WD associated region WD40 PF00400.27 OAJ07148.1 - 2.7e-40 134.8 9.3 3.6e-10 39.3 0.2 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 OAJ07148.1 - 0.02 13.0 0.6 5.7 4.9 0.0 3.1 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Phlebovirus_G2 PF07245.6 OAJ07148.1 - 0.11 10.7 0.0 0.19 9.9 0.0 1.3 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Paf1 PF03985.8 OAJ07221.1 - 0.019 13.7 6.7 0.025 13.3 4.7 1.2 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.7 OAJ07221.1 - 0.068 13.0 4.7 0.072 12.9 3.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spt5_N PF11942.3 OAJ07221.1 - 0.091 13.3 12.4 0.16 12.6 8.6 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF2072 PF09845.4 OAJ07221.1 - 0.94 9.4 6.8 0.95 9.3 3.8 1.7 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) CDC45 PF02724.9 OAJ07221.1 - 1.5 6.7 10.5 1.9 6.3 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3381 PF11861.3 OAJ07221.1 - 2.2 7.7 11.7 3.9 6.9 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Herpes_DNAp_acc PF04929.7 OAJ07221.1 - 2.4 7.0 6.8 2.8 6.8 4.7 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CCDC-167 PF15188.1 OAJ07299.1 - 0.49 10.3 2.2 0.92 9.4 1.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF2146 PF10220.4 OAJ07299.1 - 6.5 4.5 7.4 8.4 4.2 5.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) PrpF PF04303.8 OAJ07382.1 - 8.5e-48 162.9 0.2 1.2e-33 116.3 0.0 2.5 2 1 0 2 2 2 2 PrpF protein Ribosomal_L2_C PF03947.13 OAJ07383.1 - 5.1e-44 149.2 5.6 4.6e-32 110.5 3.3 2.6 1 1 1 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 OAJ07383.1 - 1.2e-25 89.2 0.0 2.2e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain MFS_1 PF07690.11 OAJ07388.1 - 1.5e-18 66.6 34.8 1.5e-18 66.6 24.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ07388.1 - 0.0032 16.1 17.5 0.0032 16.1 12.2 2.9 2 2 0 2 2 2 1 Sugar (and other) transporter CRT-like PF08627.5 OAJ07388.1 - 0.073 13.0 3.3 1.4 8.8 0.1 3.1 3 0 0 3 3 3 0 CRT-like COesterase PF00135.23 OAJ07390.1 - 2.1e-109 366.6 0.1 2.9e-109 366.2 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ07390.1 - 8.6e-06 25.4 0.1 0.00014 21.5 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Mtc PF03820.12 OAJ07391.1 - 1.2e-85 286.8 0.0 1.4e-85 286.6 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier gag_pre-integrs PF13976.1 OAJ07478.1 - 7.7e-07 28.6 0.3 2e-05 24.1 0.0 3.0 2 1 1 3 3 3 1 GAG-pre-integrase domain rve PF00665.21 OAJ07478.1 - 0.00051 20.1 0.1 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain UBN2 PF14223.1 OAJ07480.1 - 3.8e-07 29.8 0.0 7.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ07480.1 - 2.9e-05 23.7 1.8 2.9e-05 23.7 1.2 1.8 2 0 0 2 2 2 1 Zinc knuckle Calcipressin PF04847.7 OAJ07567.1 - 1.5e-26 93.1 0.0 1.4e-22 80.1 0.3 2.2 2 0 0 2 2 2 2 Calcipressin Septin PF00735.13 OAJ07568.1 - 2.9e-116 387.4 0.4 3.9e-116 387.0 0.3 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 OAJ07568.1 - 1.7e-08 34.4 0.0 3.5e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 OAJ07568.1 - 9.3e-08 31.4 0.0 2.3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 OAJ07568.1 - 2.7e-07 30.2 0.4 1e-05 25.0 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.17 OAJ07568.1 - 4.7e-05 22.8 0.6 0.00015 21.1 0.4 1.8 1 1 0 1 1 1 1 Ras family AAA_10 PF12846.2 OAJ07568.1 - 0.00037 20.0 0.0 0.0008 18.9 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain AIG1 PF04548.11 OAJ07568.1 - 0.0004 19.5 0.0 0.00088 18.4 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 OAJ07568.1 - 0.00042 20.8 0.1 0.0015 18.9 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 OAJ07568.1 - 0.00073 19.1 0.7 0.0015 18.1 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ07568.1 - 0.0008 19.5 1.6 0.0053 16.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.4 OAJ07568.1 - 0.001 18.5 2.0 0.017 14.5 0.4 2.9 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 OAJ07568.1 - 0.0011 19.3 0.2 0.0034 17.6 0.0 1.9 2 0 0 2 2 2 1 ABC transporter Gtr1_RagA PF04670.7 OAJ07568.1 - 0.0012 18.0 0.1 0.0035 16.5 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 OAJ07568.1 - 0.0023 17.9 0.8 0.0072 16.3 0.0 2.2 3 0 0 3 3 2 1 AAA ATPase domain MobB PF03205.9 OAJ07568.1 - 0.0027 17.3 0.2 0.0075 15.9 0.1 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 OAJ07568.1 - 0.0099 15.7 6.1 0.36 10.6 0.2 2.8 2 1 1 3 3 3 2 Dynamin family NACHT PF05729.7 OAJ07568.1 - 0.012 15.3 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 OAJ07568.1 - 0.012 15.4 0.6 0.09 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 OAJ07568.1 - 0.014 14.9 0.8 2 7.8 0.1 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 OAJ07568.1 - 0.014 14.6 0.1 0.041 13.1 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Sigma54_activat PF00158.21 OAJ07568.1 - 0.023 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 OAJ07568.1 - 0.028 14.3 0.1 0.08 12.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain T2SE PF00437.15 OAJ07568.1 - 0.029 13.2 0.6 0.14 11.0 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 OAJ07568.1 - 0.034 13.6 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 OAJ07568.1 - 0.039 13.1 0.0 0.076 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 OAJ07568.1 - 0.04 13.4 1.4 0.079 12.4 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 OAJ07568.1 - 0.041 14.1 0.5 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 OAJ07568.1 - 0.053 12.8 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.17 OAJ07568.1 - 0.077 13.1 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 OAJ07568.1 - 0.08 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 OAJ07568.1 - 0.09 12.2 3.3 0.51 9.7 0.3 2.5 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 OAJ07568.1 - 0.2 10.4 3.0 0.43 9.3 0.1 2.4 3 0 0 3 3 3 0 ArgK protein Bac_DnaA PF00308.13 OAJ07568.1 - 0.31 10.6 3.2 5.2 6.6 0.2 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_23 PF13476.1 OAJ07568.1 - 7.7 6.7 13.5 1.1e+02 3.0 9.4 2.1 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 OAJ07571.1 - 9e-46 155.4 0.0 2.2e-45 154.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ07571.1 - 2.7e-22 78.4 0.0 5.8e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 OAJ07571.1 - 5.7e-22 77.0 0.2 1.2e-21 76.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 OAJ07571.1 - 0.0015 18.4 0.0 0.0078 16.0 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 OAJ07571.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain DUF2551 PF10826.3 OAJ07636.1 - 0.013 15.3 0.6 0.019 14.8 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2551) DUF4006 PF13179.1 OAJ07636.1 - 0.056 13.0 0.4 0.085 12.4 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Cation_ATPase_C PF00689.16 OAJ07636.1 - 0.083 12.4 0.1 0.085 12.3 0.1 1.0 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Asp_protease_2 PF13650.1 OAJ07637.1 - 0.00016 22.0 0.2 0.00029 21.2 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ07637.1 - 0.0048 16.7 0.1 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ07637.1 - 0.012 15.4 0.1 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 OAJ07638.1 - 5.4e-17 61.8 0.1 1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ07638.1 - 2.2e-12 47.1 0.0 4.6e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain dUTPase PF00692.14 OAJ07638.1 - 0.19 11.1 0.0 0.39 10.1 0.0 1.4 1 0 0 1 1 1 0 dUTPase Orbi_NS3 PF01616.11 OAJ07717.1 - 0.004 16.1 2.5 0.18 10.7 0.1 2.5 2 0 0 2 2 2 1 Orbivirus NS3 IncA PF04156.9 OAJ07717.1 - 0.044 13.3 25.5 0.081 12.5 0.6 2.6 2 1 0 2 2 2 0 IncA protein TEBP_beta PF07404.6 OAJ07717.1 - 0.11 11.5 4.5 0.2 10.7 3.1 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) TBPIP PF07106.8 OAJ07717.1 - 0.25 10.8 15.3 1.1 8.7 0.5 3.2 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 OAJ07717.1 - 0.29 11.3 3.8 2.5 8.4 0.1 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Vfa1 PF08432.5 OAJ07717.1 - 1.9 8.4 11.3 4.6 7.2 0.1 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.1 OAJ07717.1 - 2.1 7.2 22.2 1.9 7.3 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FH2 PF02181.18 OAJ07717.1 - 2.3 6.9 7.1 0.19 10.5 0.9 1.9 2 1 1 3 3 3 0 Formin Homology 2 Domain DUF972 PF06156.8 OAJ07717.1 - 2.7 8.3 17.2 9.4 6.6 1.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Prefoldin_2 PF01920.15 OAJ07717.1 - 3.6 7.3 13.7 5.8 6.7 0.2 3.2 3 0 0 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.5 OAJ07717.1 - 3.6 7.6 7.9 25 4.9 3.5 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DivIVA PF05103.8 OAJ07717.1 - 4.2 7.4 23.3 0.42 10.6 4.9 3.2 2 1 1 3 3 3 0 DivIVA protein Latarcin PF10279.4 OAJ07717.1 - 4.7 7.4 7.0 4.7 7.4 0.3 2.5 2 0 0 2 2 2 0 Latarcin precursor TMF_DNA_bd PF12329.3 OAJ07717.1 - 5.1 6.9 21.9 1.2 8.9 1.4 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 OAJ07717.1 - 7.3 5.4 20.9 5.5 5.8 10.2 2.4 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Phage_GP20 PF06810.6 OAJ07717.1 - 8 5.8 16.5 0.81 9.1 0.9 3.2 2 1 1 3 3 3 0 Phage minor structural protein GP20 HALZ PF02183.13 OAJ07717.1 - 8.9 6.1 7.4 11 5.7 0.9 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Seryl_tRNA_N PF02403.17 OAJ07717.1 - 9 6.3 16.0 9 6.3 1.0 3.1 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 OAJ07717.1 - 9.6 5.7 20.8 0.39 10.2 0.6 3.3 3 0 0 3 3 3 0 Septum formation initiator CAP PF00188.21 OAJ07724.1 - 1.1e-24 87.2 2.5 1.7e-24 86.6 1.7 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TAP42 PF04177.7 OAJ07815.1 - 5.4e-59 199.8 0.0 2.3e-58 197.7 0.0 1.7 1 1 0 1 1 1 1 TAP42-like family Nop PF01798.13 OAJ07815.1 - 0.053 12.8 0.5 0.12 11.7 0.3 1.5 1 0 0 1 1 1 0 Putative snoRNA binding domain NAD_binding_10 PF13460.1 OAJ07816.1 - 3.9e-18 66.1 0.0 5.5e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAJ07816.1 - 2.4e-05 23.9 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 OAJ07816.1 - 0.0022 17.3 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Mito_carr PF00153.22 OAJ07819.1 - 1.7e-66 219.9 4.2 4e-22 77.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF883 PF05957.8 OAJ07820.1 - 0.035 14.5 0.8 0.035 14.5 0.5 2.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Vac14_Fab1_bd PF12755.2 OAJ07907.1 - 1.2e-07 32.0 0.1 0.00017 21.9 0.0 3.1 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region SOG2 PF10428.4 OAJ07908.1 - 5.4 5.5 9.2 7 5.1 6.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Dimer_Tnp_hAT PF05699.9 OAJ07910.1 - 5.4e-08 32.3 0.0 1.5e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.22 OAJ08017.1 - 3.8e-17 62.3 0.0 7.4e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08017.1 - 4.3e-14 52.6 0.0 1.1e-13 51.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ08017.1 - 0.00018 21.9 0.0 0.00056 20.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ08017.1 - 0.0088 15.9 0.0 0.021 14.7 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ08017.1 - 0.047 13.5 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease MKT1_C PF12246.3 OAJ08019.1 - 3.8e-64 216.0 0.0 7.3e-63 211.8 0.0 2.5 3 0 0 3 3 3 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 OAJ08019.1 - 2.6e-21 75.7 0.0 5.9e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 OAJ08019.1 - 5.5e-08 32.9 0.0 1.5e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 OAJ08019.1 - 2.6e-05 24.1 0.0 6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region Phostensin_N PF13916.1 OAJ08019.1 - 0.051 13.5 1.1 0.16 11.9 0.8 1.8 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal PB1 PF00564.19 OAJ08020.1 - 5.9e-05 22.6 0.0 0.0001 21.8 0.0 1.5 1 0 0 1 1 1 1 PB1 domain Zip PF02535.17 OAJ08020.1 - 0.11 11.5 2.0 0.11 11.4 1.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CBS PF00571.23 OAJ08020.1 - 0.12 12.2 0.4 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 CBS domain SDA1 PF05285.7 OAJ08020.1 - 1.2 8.3 6.1 1.5 8.0 4.2 1.1 1 0 0 1 1 1 0 SDA1 SMN PF06003.7 OAJ08020.1 - 9 5.3 11.4 12 4.9 7.9 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) TPR_2 PF07719.12 OAJ08025.1 - 1.9e-07 30.4 6.5 0.015 15.1 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ08025.1 - 7e-06 25.4 6.8 0.016 14.8 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ08025.1 - 8.6e-06 25.1 0.2 0.023 14.4 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ08025.1 - 1.4e-05 24.6 9.5 0.051 13.2 0.0 5.1 4 1 2 6 6 6 2 TPR repeat DUF3856 PF12968.2 OAJ08025.1 - 0.0013 18.5 1.0 1.5 8.6 0.1 3.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF3856) Apc5 PF12862.2 OAJ08025.1 - 0.0038 17.0 8.1 0.015 15.0 0.1 4.5 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 5 Apc3 PF12895.2 OAJ08025.1 - 0.0063 16.6 2.7 3.1 8.0 0.0 3.6 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 OAJ08025.1 - 0.013 15.4 1.1 0.013 15.4 0.8 6.3 6 1 3 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ08025.1 - 0.069 12.9 3.4 3.9 7.4 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ08025.1 - 0.7 10.2 12.1 4.7 7.6 1.0 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ08025.1 - 0.71 10.6 0.0 0.71 10.6 0.0 7.4 7 2 2 9 9 8 0 Tetratricopeptide repeat MutS_III PF05192.13 OAJ08025.1 - 1.4 8.6 10.8 16 5.1 4.8 3.3 1 1 1 2 2 2 0 MutS domain III TPR_4 PF07721.9 OAJ08025.1 - 3.7 8.2 24.4 1.7 9.3 0.1 6.5 6 0 0 6 6 5 0 Tetratricopeptide repeat tRNA-synt_1c_C PF03950.13 OAJ08026.1 - 0.056 13.1 0.0 0.066 12.8 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain DOMON PF03351.12 OAJ08030.1 - 0.00019 21.3 0.2 0.0003 20.7 0.1 1.3 1 0 0 1 1 1 1 DOMON domain DUF4079 PF13301.1 OAJ08030.1 - 0.046 13.7 0.4 0.096 12.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) UCH PF00443.24 OAJ08035.1 - 6.3e-38 130.4 0.0 2.4e-36 125.2 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ08035.1 - 1.5e-11 44.3 0.0 1e-10 41.5 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ras PF00071.17 OAJ08036.1 - 3e-52 176.2 0.3 3.5e-52 176.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ08036.1 - 1.6e-18 67.3 0.0 2e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ08036.1 - 3.4e-16 58.9 0.0 4.8e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ08036.1 - 6.7e-05 22.1 0.0 8.3e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 OAJ08036.1 - 0.0002 21.3 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAJ08036.1 - 0.00028 20.4 0.1 0.0021 17.5 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 OAJ08036.1 - 0.0012 18.1 0.1 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit HTH_DeoR PF08220.7 OAJ08038.1 - 0.045 13.2 0.1 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Nop14 PF04147.7 OAJ08039.1 - 5.3e-06 24.6 16.0 5.4e-06 24.6 11.1 1.2 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 OAJ08039.1 - 0.017 14.4 20.7 0.025 13.8 14.4 1.3 1 0 0 1 1 1 0 SDA1 Herpes_TAF50 PF03326.8 OAJ08039.1 - 0.044 12.7 5.3 0.062 12.2 3.6 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) CDC45 PF02724.9 OAJ08039.1 - 0.085 10.8 13.8 0.11 10.4 9.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 OAJ08039.1 - 1.2 8.4 15.5 1.9 7.8 10.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Herpes_LMP1 PF05297.6 OAJ08039.1 - 1.5 7.6 9.4 2.1 7.1 6.5 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) YL1 PF05764.8 OAJ08039.1 - 1.6 8.2 31.1 0.05 13.2 15.9 2.1 1 1 0 2 2 2 0 YL1 nuclear protein VID27 PF08553.5 OAJ08039.1 - 2.5 6.2 10.2 3.1 5.9 7.1 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Lin-8 PF03353.10 OAJ08039.1 - 3.3 6.9 12.8 0.26 10.5 5.2 1.7 1 1 1 2 2 2 0 Ras-mediated vulval-induction antagonist RRN3 PF05327.6 OAJ08039.1 - 7 4.6 11.3 8.9 4.2 7.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-CCHC PF00098.18 OAJ08040.1 - 0.0041 16.9 2.0 0.0065 16.3 1.4 1.3 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.3 OAJ08040.1 - 0.036 13.9 0.4 0.036 13.9 0.3 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Retrotrans_gag PF03732.12 OAJ08040.1 - 0.054 13.5 0.0 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_3 PF13917.1 OAJ08040.1 - 0.15 11.8 0.5 0.29 10.9 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 OAJ08040.1 - 0.2 11.3 2.5 0.52 10.0 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 OAJ08043.1 - 6.2e-11 42.0 0.0 6.8e-10 38.6 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 OAJ08043.1 - 0.0076 16.1 1.2 0.015 15.1 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.1 OAJ08043.1 - 0.016 15.0 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 OAJ08043.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4511 PF14974.1 OAJ08043.1 - 0.057 13.1 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4511) gag_pre-integrs PF13976.1 OAJ08045.1 - 0.034 13.7 0.1 2.6 7.7 0.0 2.9 3 0 0 3 3 3 0 GAG-pre-integrase domain zf-H2C2 PF09337.5 OAJ08045.1 - 0.18 11.2 0.5 0.31 10.4 0.4 1.4 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Sec20 PF03908.8 OAJ08047.1 - 4.6e-19 67.9 1.3 1.1e-18 66.7 0.9 1.6 1 0 0 1 1 1 1 Sec20 DUF2776 PF10951.3 OAJ08047.1 - 0.021 13.9 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) YrhK PF14145.1 OAJ08047.1 - 0.54 9.9 2.6 0.33 10.6 0.3 1.8 2 0 0 2 2 2 0 YrhK-like protein DAHP_synth_1 PF00793.15 OAJ08048.1 - 1.6e-93 312.3 0.0 2e-93 312.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family rve PF00665.21 OAJ08055.1 - 4.5e-14 52.5 0.0 1.2e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ08055.1 - 5.6e-13 48.7 0.0 1.3e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) KfrA_N PF11740.3 OAJ08055.1 - 0.24 11.8 8.3 1 9.8 0.8 2.7 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DcpS_C PF11969.3 OAJ08058.1 - 4.6e-27 94.5 0.0 7e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 OAJ08058.1 - 1.1e-14 54.7 0.0 2.3e-14 53.6 0.0 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Abhydrolase_6 PF12697.2 OAJ08060.1 - 3.7e-22 79.3 0.2 5.2e-22 78.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ08060.1 - 1.6e-08 34.3 0.2 3.9e-08 33.1 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ08060.1 - 2.9e-06 26.9 0.0 7.6e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Gly-rich_Ago1 PF12764.2 OAJ08064.1 - 0.032 14.8 2.3 0.032 14.8 1.6 2.0 2 0 0 2 2 2 0 Glycine-rich region of argonaut DUF2702 PF10863.3 OAJ08064.1 - 0.058 13.1 0.4 0.058 13.1 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2702) IncA PF04156.9 OAJ08064.1 - 0.062 12.8 7.4 0.014 14.9 2.3 2.1 2 0 0 2 2 2 0 IncA protein TMCO5 PF14992.1 OAJ08064.1 - 1.6 7.7 8.0 0.37 9.8 2.8 1.8 2 0 0 2 2 2 0 TMCO5 family DUF972 PF06156.8 OAJ08064.1 - 3.7 7.9 9.8 1.1 9.6 2.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Syntaxin PF00804.20 OAJ08064.1 - 4.7 7.4 12.4 3.1 7.9 0.1 3.2 2 1 0 2 2 2 0 Syntaxin Hydrolase_like PF13242.1 OAJ08069.1 - 1.3e-20 72.8 0.0 1.7e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 HAD-hyrolase-like Ctr PF04145.10 OAJ08071.1 - 0.67 9.9 0.0 0.67 9.9 0.0 2.8 3 0 0 3 3 3 0 Ctr copper transporter family MARVEL PF01284.18 OAJ08071.1 - 5.6 6.7 14.1 12 5.6 9.8 1.6 1 0 0 1 1 1 0 Membrane-associating domain HEM4 PF02602.10 OAJ08077.1 - 5.8e-17 61.7 0.6 4.4e-08 32.6 0.0 4.9 5 0 0 5 5 5 4 Uroporphyrinogen-III synthase HemD DEAD PF00270.24 OAJ08078.1 - 2.3e-15 56.5 0.0 4.3e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ08078.1 - 1.6e-11 44.3 0.3 3.4e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 OAJ08078.1 - 8.9e-07 27.9 0.1 8.9e-07 27.9 0.1 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.1 OAJ08078.1 - 0.00023 21.3 0.0 0.0013 18.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 OAJ08078.1 - 0.0057 15.9 0.0 0.0088 15.2 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.4 OAJ08078.1 - 0.0065 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) CALCOCO1 PF07888.6 OAJ08078.1 - 0.013 13.8 0.5 0.02 13.2 0.4 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Troponin PF00992.15 OAJ08078.1 - 0.014 15.4 2.1 0.036 14.1 1.4 1.7 1 0 0 1 1 1 0 Troponin DUF904 PF06005.7 OAJ08078.1 - 0.03 14.5 1.6 0.076 13.3 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Acetyltransf_11 PF13720.1 OAJ08078.1 - 0.095 12.9 0.6 0.86 9.8 0.1 2.4 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Pkinase PF00069.20 OAJ08083.1 - 1.1e-23 83.7 3.6 1.5e-19 70.1 0.2 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ08083.1 - 1.3e-15 57.1 0.0 4.8e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase zf-RING_2 PF13639.1 OAJ08084.1 - 6.5e-08 32.2 7.8 6.5e-08 32.2 5.4 2.6 2 0 0 2 2 2 1 Ring finger domain IBR PF01485.16 OAJ08084.1 - 6.5e-08 32.3 0.8 6.5e-08 32.3 0.5 3.8 2 1 2 4 4 4 1 IBR domain zf-C3HC4_2 PF13923.1 OAJ08084.1 - 6e-07 29.3 7.9 6e-07 29.3 5.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RWD PF05773.17 OAJ08084.1 - 7.5e-07 29.0 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_5 PF14634.1 OAJ08084.1 - 4.4e-05 23.1 7.2 4.4e-05 23.1 5.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 OAJ08084.1 - 0.00012 21.6 6.5 0.00012 21.6 4.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAJ08084.1 - 0.00024 20.7 2.8 0.00024 20.7 1.9 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 OAJ08084.1 - 0.0043 16.8 6.1 0.03 14.0 4.2 2.3 1 1 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 OAJ08084.1 - 0.27 11.1 13.8 0.25 11.2 3.7 3.2 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 OAJ08084.1 - 0.76 9.4 15.5 0.14 11.7 1.0 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ribbon_3 PF13248.1 OAJ08084.1 - 4.3 6.6 10.1 7.5 5.9 2.5 4.0 3 1 0 3 3 3 0 zinc-ribbon domain ParA PF10609.4 OAJ08085.1 - 5e-31 106.4 0.0 9.2e-31 105.5 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 OAJ08085.1 - 1.1e-10 41.2 0.0 2.8e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 OAJ08085.1 - 4.9e-06 26.5 0.0 0.00016 21.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 OAJ08085.1 - 0.00025 20.1 1.8 0.0014 17.6 0.3 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.1 OAJ08085.1 - 0.0004 19.8 0.0 0.00091 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 OAJ08085.1 - 0.0073 15.4 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MipZ PF09140.6 OAJ08085.1 - 0.025 13.6 0.0 0.55 9.2 0.0 2.1 1 1 0 2 2 2 0 ATPase MipZ AAA_26 PF13500.1 OAJ08085.1 - 0.026 14.1 0.1 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 OAJ08085.1 - 0.097 12.6 0.2 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 OAJ08085.1 - 0.14 12.3 0.0 0.44 10.7 0.0 1.8 2 0 0 2 2 2 0 RNA helicase DUF4380 PF14315.1 OAJ08089.1 - 0.0025 17.0 0.1 0.0031 16.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4380) RVT_1 PF00078.22 OAJ08098.1 - 6.9e-17 61.5 0.0 1.1e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 OAJ08098.1 - 0.00029 20.5 0.3 0.0051 16.6 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAJ08098.1 - 0.0011 19.4 0.0 0.0038 17.7 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ08098.1 - 0.036 13.9 0.0 0.083 12.8 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease Alpha_GJ PF03229.8 OAJ08100.1 - 6.6 7.0 8.1 46 4.3 5.9 2.0 2 0 0 2 2 2 0 Alphavirus glycoprotein J RNase_H PF00075.19 OAJ08101.1 - 2.6e-13 50.4 0.1 3.8e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 RNase H rve PF00665.21 OAJ08106.1 - 2.7e-06 27.4 0.0 3.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Pyr_redox_2 PF07992.9 OAJ08108.1 - 0.12 12.2 0.1 1.8 8.3 0.1 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.27 OAJ08112.1 - 7.1e-24 82.7 11.1 2.5e-07 30.3 0.7 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 OAJ08112.1 - 0.084 10.9 0.0 0.92 7.5 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 BAF1_ABF1 PF04684.8 OAJ08113.1 - 0.17 10.7 4.6 0.55 9.0 0.6 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF1370 PF07114.6 OAJ08114.1 - 0.79 8.9 29.6 0.63 9.2 5.9 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1370) RVT_1 PF00078.22 OAJ08121.1 - 1.2e-16 60.7 0.0 2.4e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08121.1 - 3.9e-08 33.4 0.0 1.8e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Exc PF07825.6 OAJ08121.1 - 0.45 10.3 2.9 0.4 10.4 0.4 2.1 2 0 0 2 2 2 0 Excisionase-like protein Asp_protease_2 PF13650.1 OAJ08123.1 - 5.3e-05 23.6 0.0 0.00014 22.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ08123.1 - 0.003 17.4 0.0 0.0082 16.0 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ08123.1 - 0.018 14.8 0.3 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Zn_protease PF05618.6 OAJ08123.1 - 0.053 13.1 0.9 2.8 7.6 0.0 2.8 3 0 0 3 3 3 0 Putative ATP-dependant zinc protease H_lectin PF09458.5 OAJ08129.1 - 0.038 13.6 0.0 0.27 10.9 0.0 2.1 2 1 0 2 2 2 0 H-type lectin domain DUF768 PF05589.6 OAJ08129.1 - 0.13 12.2 0.7 0.51 10.3 0.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF768) Actin PF00022.14 OAJ08131.1 - 5.3e-17 61.3 0.0 6.3e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 Actin RVT_2 PF07727.9 OAJ08140.1 - 6.5e-82 274.1 0.0 9e-82 273.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08140.1 - 2.6e-25 88.8 0.0 5.4e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ08140.1 - 0.00013 21.4 0.0 0.00049 19.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ08140.1 - 0.0044 16.6 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_1 PF00078.22 OAJ08140.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 OAJ08141.1 - 5.4e-07 29.2 6.9 1.1e-06 28.2 4.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ08141.1 - 0.03 14.0 6.3 0.052 13.2 4.4 1.4 1 0 0 1 1 1 0 Zinc knuckle GRP PF07172.6 OAJ08141.1 - 0.044 14.2 15.5 0.059 13.8 10.8 1.3 1 0 0 1 1 1 0 Glycine rich protein family SWIM PF04434.12 OAJ08143.1 - 0.00018 20.9 0.2 0.00034 19.9 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger EPSP_synthase PF00275.15 OAJ08144.1 - 0.0029 16.0 0.0 0.0048 15.3 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) CHAT PF12770.2 OAJ08144.1 - 0.071 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 CHAT domain PK_C PF02887.11 OAJ08144.1 - 0.21 11.1 3.4 2.3 7.8 0.1 2.5 2 1 1 3 3 3 0 Pyruvate kinase, alpha/beta domain zf-C2H2_4 PF13894.1 OAJ08148.1 - 0.021 15.1 11.5 0.16 12.4 0.3 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ08148.1 - 0.26 11.6 6.4 4.2 7.8 1.0 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ08148.1 - 0.93 9.9 14.7 0.7 10.3 0.5 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Sterol_MT_C PF08498.5 OAJ08150.1 - 2.2e-27 94.7 0.1 3.3e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 OAJ08150.1 - 3.8e-18 65.5 0.0 5.2e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ08150.1 - 1.1e-16 61.1 0.0 2.4e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ08150.1 - 3.6e-15 56.0 0.0 6e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAJ08150.1 - 1.4e-14 53.8 0.0 2e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 OAJ08150.1 - 3.9e-13 49.7 0.3 8.4e-12 45.4 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ08150.1 - 4.8e-13 49.6 0.0 7.5e-12 45.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ08150.1 - 1.1e-11 45.0 0.1 4.3e-11 43.0 0.0 2.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ08150.1 - 2.5e-11 43.6 0.2 1.1e-10 41.5 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 OAJ08150.1 - 2.2e-05 24.1 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 OAJ08150.1 - 3e-05 23.4 0.0 6.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 OAJ08150.1 - 3.2e-05 23.5 0.2 5.1e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.1 OAJ08150.1 - 8.7e-05 23.3 0.0 0.00027 21.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 OAJ08150.1 - 0.00099 18.2 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.8 OAJ08150.1 - 0.0032 16.6 0.0 0.0079 15.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Spermine_synth PF01564.12 OAJ08150.1 - 0.011 14.6 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase UPF0020 PF01170.13 OAJ08150.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 OAJ08150.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain HRM PF02793.17 OAJ08150.1 - 0.025 14.5 1.1 0.058 13.4 0.8 1.5 1 0 0 1 1 1 0 Hormone receptor domain MetW PF07021.7 OAJ08150.1 - 0.03 13.6 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.13 OAJ08150.1 - 0.038 13.1 0.0 0.069 12.3 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase RrnaAD PF00398.15 OAJ08150.1 - 0.063 12.2 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 OAJ08150.1 - 0.11 11.5 0.0 0.26 10.2 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase SSF PF00474.12 OAJ08151.1 - 5.1e-24 84.6 34.4 5.1e-24 84.6 23.9 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family Mid2 PF04478.7 OAJ08151.1 - 1.3 8.3 3.8 61 2.9 0.1 3.5 3 0 0 3 3 3 0 Mid2 like cell wall stress sensor Ribosomal_L10 PF00466.15 OAJ08154.1 - 0.002 17.9 0.0 0.0043 16.9 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L10 MCPVI PF02993.9 OAJ08155.1 - 0.17 12.0 2.6 0.19 11.8 1.8 1.0 1 0 0 1 1 1 0 Minor capsid protein VI Transket_pyr PF02779.19 OAJ08156.1 - 6.9e-37 126.6 0.0 1.1e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 OAJ08156.1 - 1.6e-27 95.9 0.0 2e-26 92.3 0.0 2.3 1 1 0 1 1 1 1 Transketolase, C-terminal domain Ras PF00071.17 OAJ08159.1 - 2.6e-65 218.7 0.0 3e-65 218.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ08159.1 - 1.6e-19 70.5 0.0 2.2e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ08159.1 - 2e-13 49.9 0.0 2.4e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ08159.1 - 3.5e-05 23.0 0.0 4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 OAJ08159.1 - 3.9e-05 23.1 0.0 0.0001 21.8 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ08159.1 - 0.0005 20.0 0.0 0.00074 19.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 OAJ08159.1 - 0.027 14.4 0.0 0.084 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.5 OAJ08159.1 - 0.03 13.5 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 OAJ08159.1 - 0.039 13.1 0.0 0.073 12.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 OAJ08159.1 - 0.044 13.3 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 OAJ08159.1 - 0.045 13.9 0.1 0.58 10.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 OAJ08159.1 - 0.055 12.7 0.0 3.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.1 OAJ08159.1 - 0.068 13.3 0.0 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 OAJ08159.1 - 0.081 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MCM PF00493.18 OAJ08159.1 - 0.12 11.1 0.0 0.36 9.5 0.0 1.7 2 0 0 2 2 2 0 MCM2/3/5 family Peptidase_M1 PF01433.15 OAJ08160.1 - 5.1e-60 203.5 0.0 7e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 OAJ08160.1 - 8.4e-44 148.6 0.0 1.5e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 OAJ08160.1 - 1.9e-10 40.8 0.0 3.6e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily RR_TM4-6 PF06459.7 OAJ08169.1 - 1.9 8.2 5.8 3.4 7.4 4.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.3 OAJ08169.1 - 3.6 6.2 9.4 5.3 5.6 6.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Hid1 PF12722.2 OAJ08169.1 - 3.7 5.1 4.8 5.6 4.5 3.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2201_N PF13203.1 OAJ08169.1 - 6 5.9 13.5 0.43 9.6 5.7 1.7 2 0 0 2 2 2 0 Putative metallopeptidase domain MFS_1 PF07690.11 OAJ08170.1 - 5.5e-36 124.0 41.3 5.5e-36 124.0 28.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ08170.1 - 8.2e-06 24.6 24.7 0.0002 20.0 17.2 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter RVT_1 PF00078.22 OAJ08174.1 - 3.6e-20 72.2 0.0 6.2e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08174.1 - 3.5e-13 49.7 0.0 9.7e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ08174.1 - 0.0021 18.5 0.0 0.0051 17.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ08174.1 - 0.061 13.2 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ08174.1 - 0.084 12.7 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Ras PF00071.17 OAJ08181.1 - 8.1e-32 109.8 0.0 1.3e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ08181.1 - 4.8e-10 39.9 0.0 9.1e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Tannase PF07519.6 OAJ08181.1 - 5.3e-10 38.5 0.4 8.7e-10 37.8 0.3 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase GTP_EFTU PF00009.22 OAJ08181.1 - 0.026 13.9 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF2520 PF10728.4 OAJ08181.1 - 0.059 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Phage_integrase PF00589.17 OAJ08183.1 - 0.0029 17.2 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 OAJ08184.1 - 0.0058 16.0 0.0 0.014 14.7 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_transf_15 PF01793.11 OAJ08187.1 - 0.028 13.3 0.2 0.031 13.2 0.1 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Macoilin PF09726.4 OAJ08188.1 - 0.016 13.4 7.2 0.015 13.5 5.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Inp1 PF12634.2 OAJ08188.1 - 0.02 14.5 2.0 0.022 14.4 1.4 1.1 1 0 0 1 1 1 0 Inheritance of peroxisomes protein 1 DUF3292 PF11696.3 OAJ08188.1 - 0.078 10.8 1.0 0.076 10.8 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF4614 PF15391.1 OAJ08188.1 - 0.091 12.5 9.4 0.094 12.4 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Asp_protease_2 PF13650.1 OAJ08188.1 - 0.14 12.7 0.4 0.3 11.6 0.1 1.7 1 1 1 2 2 2 0 Aspartyl protease RNA_pol_Rpc34 PF05158.7 OAJ08188.1 - 0.33 10.0 2.9 0.62 9.1 0.0 1.9 1 1 1 2 2 2 0 RNA polymerase Rpc34 subunit DDHD PF02862.12 OAJ08188.1 - 0.67 9.7 5.7 0.67 9.7 3.9 1.1 1 0 0 1 1 1 0 DDHD domain SPC25 PF06703.6 OAJ08188.1 - 0.73 9.4 2.9 0.91 9.0 2.0 1.1 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Mcm10 PF09332.6 OAJ08188.1 - 0.79 9.0 6.5 0.8 8.9 4.5 1.0 1 0 0 1 1 1 0 Mcm10 replication factor DUF3827 PF12877.2 OAJ08188.1 - 1.2 7.2 5.6 0.95 7.4 3.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Sec3_C PF09763.4 OAJ08188.1 - 3.4 5.6 7.9 3.6 5.6 5.5 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 DNA_pol_viral_N PF00242.12 OAJ08188.1 - 4.4 6.2 10.5 4.6 6.1 7.3 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF572 PF04502.8 OAJ08188.1 - 8.5 5.4 9.7 9 5.4 6.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Rootletin PF15035.1 OAJ08189.1 - 0.0033 17.4 11.5 0.0033 17.4 8.0 4.0 1 1 1 3 3 3 1 Ciliary rootlet component, centrosome cohesion DUF4200 PF13863.1 OAJ08189.1 - 0.0067 16.3 9.0 0.0067 16.3 6.3 4.6 4 1 0 4 4 4 1 Domain of unknown function (DUF4200) Myosin_tail_1 PF01576.14 OAJ08189.1 - 0.0086 13.8 36.2 0.085 10.5 22.1 2.4 2 0 0 2 2 2 2 Myosin tail SseC PF04888.7 OAJ08189.1 - 1.5 8.0 0.0 1.5 8.0 0.0 3.6 5 0 0 5 5 5 0 Secretion system effector C (SseC) like family TPR_MLP1_2 PF07926.7 OAJ08189.1 - 3.2 7.5 40.7 3.1 7.5 0.2 4.4 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein TMEM171 PF15471.1 OAJ08189.1 - 3.7 6.2 0.0 3.7 6.2 0.0 2.9 3 0 0 3 3 3 0 Transmembrane protein family 171 DivIC PF04977.10 OAJ08189.1 - 8.5 5.9 37.1 0.014 14.9 4.2 5.8 4 1 1 5 5 5 0 Septum formation initiator Pyr_redox_2 PF07992.9 OAJ08191.1 - 1.2e-39 136.2 0.6 2.2e-39 135.4 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 OAJ08191.1 - 3.8e-33 113.8 1.7 5.8e-33 113.2 0.8 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 OAJ08191.1 - 2.2e-19 69.6 4.1 3.6e-17 62.5 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAJ08191.1 - 4e-12 46.6 0.4 0.00016 21.8 0.5 3.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ08191.1 - 1.1e-06 27.4 1.7 0.017 13.6 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.2 OAJ08191.1 - 9.1e-06 25.0 0.2 5e-05 22.5 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ08191.1 - 0.0033 17.4 0.6 0.014 15.4 0.4 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAJ08191.1 - 0.0042 16.0 0.0 0.017 14.0 0.0 1.9 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 OAJ08191.1 - 0.0043 16.0 5.1 1.5 7.6 1.2 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 OAJ08191.1 - 0.0053 15.8 0.2 0.012 14.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 OAJ08191.1 - 0.0073 15.2 0.9 0.062 12.1 0.4 2.3 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 OAJ08191.1 - 0.015 14.9 0.8 0.49 10.0 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Dimerisation PF08100.6 OAJ08196.1 - 0.062 13.1 0.2 21 5.0 0.0 2.9 1 1 2 3 3 3 0 Dimerisation domain UQ_con PF00179.21 OAJ08199.1 - 6.9e-15 54.7 0.1 1.2e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ08199.1 - 0.033 13.9 0.2 0.58 9.9 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic E2 family B UEV PF05743.8 OAJ08199.1 - 0.039 13.6 0.1 0.099 12.3 0.1 1.6 1 1 0 1 1 1 0 UEV domain UPF0029 PF01205.14 OAJ08200.1 - 8e-16 57.6 0.0 2.8e-15 55.9 0.0 2.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF605 PF04652.11 OAJ08200.1 - 0.086 12.2 36.1 0.52 9.6 16.6 2.3 2 0 0 2 2 2 0 Vta1 like Con-6 PF10346.4 OAJ08201.1 - 5.3e-09 35.3 0.8 9.6e-09 34.5 0.5 1.5 1 1 0 1 1 1 1 Conidiation protein 6 RNase_T PF00929.19 OAJ08203.1 - 2.6e-07 31.0 0.0 3.2e-06 27.5 0.0 2.6 3 0 0 3 3 3 1 Exonuclease MBOAT PF03062.14 OAJ08204.1 - 4.6e-41 140.9 0.0 2e-40 138.8 0.0 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family HA2 PF04408.18 OAJ08209.1 - 7e-19 67.7 0.1 2.4e-18 66.0 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ08209.1 - 5.3e-13 48.6 0.2 1.3e-12 47.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 OAJ08209.1 - 1.7e-09 37.4 0.0 4.2e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 OAJ08209.1 - 4e-09 36.1 0.0 8.3e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ08209.1 - 1.8e-07 31.3 0.2 9.8e-07 28.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 OAJ08209.1 - 0.011 14.6 0.0 0.025 13.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 OAJ08209.1 - 0.019 14.6 0.0 0.093 12.4 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_29 PF13555.1 OAJ08209.1 - 0.03 13.8 0.0 0.079 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 OAJ08209.1 - 0.047 12.7 0.0 0.098 11.7 0.0 1.5 1 0 0 1 1 1 0 KaiC Arch_ATPase PF01637.13 OAJ08209.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase AAA_23 PF13476.1 OAJ08209.1 - 0.2 11.9 0.0 0.75 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 OAJ08209.1 - 0.31 9.8 0.0 0.56 9.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Fer2 PF00111.22 OAJ08210.1 - 4.5e-12 45.5 0.3 5.8e-12 45.1 0.2 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain SPT2 PF08243.6 OAJ08211.1 - 0.061 13.6 23.2 0.2 11.9 16.1 1.9 1 1 0 1 1 1 0 SPT2 chromatin protein Herpes_UL32 PF06070.6 OAJ08211.1 - 6.2 5.1 28.8 8.2 4.7 20.0 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 FYVE PF01363.16 OAJ08213.1 - 5.5e-15 55.0 8.8 7.3e-15 54.6 6.1 1.2 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 OAJ08213.1 - 0.019 14.8 7.5 0.045 13.6 5.2 1.5 1 1 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.2 OAJ08213.1 - 0.067 13.0 7.4 0.64 9.8 0.2 2.5 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.1 OAJ08213.1 - 0.29 10.9 6.1 0.46 10.2 2.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Cript PF10235.4 OAJ08213.1 - 1.8 8.9 4.7 0.33 11.3 0.8 1.6 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT HypA PF01155.14 OAJ08213.1 - 2 8.1 7.9 1.6 8.4 2.3 2.3 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-B_box PF00643.19 OAJ08213.1 - 4.1 7.3 11.4 10 6.0 5.4 2.4 2 1 0 2 2 2 0 B-box zinc finger IBR PF01485.16 OAJ08213.1 - 7.7 6.4 10.4 8.8 6.2 5.3 2.1 2 1 0 2 2 2 0 IBR domain zf-RING_2 PF13639.1 OAJ08214.1 - 0.0015 18.3 0.3 0.0028 17.4 0.2 1.4 1 0 0 1 1 1 1 Ring finger domain Hist_deacetyl PF00850.14 OAJ08218.1 - 4.4e-90 302.1 0.0 6.9e-90 301.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 OAJ08218.1 - 0.0011 18.3 0.0 0.0071 15.7 0.0 2.1 1 1 0 1 1 1 1 Arb2 domain HTH_IclR PF09339.5 OAJ08218.1 - 0.073 12.6 0.2 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain V_ATPase_I PF01496.14 OAJ08222.1 - 2.5e-272 905.2 0.0 2.8e-272 905.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.3 OAJ08222.1 - 0.11 12.2 1.6 0.22 11.2 1.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Prefoldin_2 PF01920.15 OAJ08222.1 - 0.15 11.8 4.0 0.059 13.1 0.3 2.1 3 0 0 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.5 OAJ08222.1 - 0.65 10.1 4.7 0.43 10.6 1.4 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FTA4 PF13093.1 OAJ08222.1 - 0.72 9.2 8.4 7.3 5.9 3.6 2.3 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DEAD PF00270.24 OAJ08223.1 - 1e-25 90.1 0.0 6.7e-25 87.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ08223.1 - 3e-25 87.8 0.0 2.1e-24 85.1 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 OAJ08223.1 - 0.00053 18.8 0.0 0.00086 18.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain CMS1 PF14617.1 OAJ08223.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Na_H_Exchanger PF00999.16 OAJ08228.1 - 8.7e-68 228.5 50.1 1.3e-67 228.0 34.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TspO_MBR PF03073.10 OAJ08228.1 - 0.021 14.3 11.2 0.011 15.3 5.2 2.3 1 1 1 2 2 2 0 TspO/MBR family Pkinase PF00069.20 OAJ08233.1 - 1.8e-69 233.8 0.0 2.2e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ08233.1 - 3.1e-29 101.8 0.0 3.7e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ08233.1 - 3.7e-06 26.1 0.0 4.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ08233.1 - 0.0091 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 OAJ08233.1 - 0.024 13.9 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 OAJ08233.1 - 0.035 13.8 0.1 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RVT_1 PF00078.22 OAJ08235.1 - 7.3e-17 61.4 0.0 1.6e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08235.1 - 2.2e-14 53.6 0.0 4.3e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ08235.1 - 0.00057 20.3 0.1 0.0017 18.7 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.12 OAJ08235.1 - 0.0015 18.5 0.2 0.0033 17.4 0.2 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein RVP PF00077.15 OAJ08235.1 - 0.0077 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease CDC45 PF02724.9 OAJ08240.1 - 0.00044 18.4 6.8 0.00055 18.1 4.7 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 OAJ08240.1 - 0.014 13.3 13.0 0.017 13.0 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 OAJ08240.1 - 0.028 14.0 8.8 0.045 13.3 6.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.7 OAJ08240.1 - 0.061 12.5 9.9 0.095 11.9 6.9 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 OAJ08240.1 - 0.26 10.3 12.7 0.44 9.5 8.8 1.3 1 0 0 1 1 1 0 BUD22 Paf1 PF03985.8 OAJ08240.1 - 0.94 8.1 12.9 1.5 7.4 8.9 1.2 1 0 0 1 1 1 0 Paf1 Vfa1 PF08432.5 OAJ08240.1 - 1.6 8.6 8.3 3.3 7.6 5.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TLP-20 PF06088.6 OAJ08240.1 - 1.7 8.3 5.9 3.8 7.1 4.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAM176 PF14851.1 OAJ08240.1 - 2.1 8.0 6.3 4.5 6.9 4.4 1.5 1 0 0 1 1 1 0 FAM176 family DUF1308 PF07000.6 OAJ08244.1 - 2.9e-20 72.2 0.0 2.8e-10 39.3 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1308) Pkinase PF00069.20 OAJ08245.1 - 6.8e-06 25.4 0.0 1.2e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ08245.1 - 0.076 12.0 0.0 0.28 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase ADIP PF11559.3 OAJ08247.1 - 0.025 14.4 2.3 2.6 7.9 0.1 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 OAJ08247.1 - 0.33 10.4 1.5 0.88 9.1 0.1 2.1 2 0 0 2 2 2 0 Septum formation initiator Cep57_MT_bd PF06657.8 OAJ08247.1 - 0.75 9.7 4.9 0.51 10.3 0.3 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Methyltransf_31 PF13847.1 OAJ08249.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ08249.1 - 0.012 16.1 0.0 0.02 15.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 OAJ08249.1 - 0.019 14.5 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 SurE PF01975.12 OAJ08257.1 - 8.2e-33 113.3 1.1 2.1e-32 112.0 0.0 2.1 1 1 1 2 2 2 1 Survival protein SurE ABC2_membrane PF01061.19 OAJ08258.1 - 1e-57 194.7 40.7 8.4e-43 145.9 14.1 2.8 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 OAJ08258.1 - 2.1e-25 88.3 0.0 5.6e-22 77.3 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 OAJ08258.1 - 6.2e-18 65.4 0.0 9.2e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 OAJ08258.1 - 3.2e-07 29.7 29.3 0.00035 19.7 2.4 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 OAJ08258.1 - 2e-05 24.7 0.0 0.022 14.7 0.0 2.4 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 OAJ08258.1 - 0.00013 21.2 0.0 0.00024 20.4 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 OAJ08258.1 - 0.00019 20.9 0.1 0.0012 18.2 0.1 2.1 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 OAJ08258.1 - 0.0015 17.9 0.0 0.0041 16.5 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 OAJ08258.1 - 0.0018 18.1 0.2 0.026 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 OAJ08258.1 - 0.0021 17.5 0.1 0.0046 16.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 OAJ08258.1 - 0.0024 18.7 0.0 0.0066 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 OAJ08258.1 - 0.0041 16.3 0.0 0.0068 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DUF1825 PF08855.5 OAJ08258.1 - 0.0098 15.8 0.9 0.63 10.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1825) AAA_16 PF13191.1 OAJ08258.1 - 0.014 15.3 0.3 0.036 14.0 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 OAJ08258.1 - 0.017 15.3 0.6 0.13 12.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 OAJ08258.1 - 0.023 14.6 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 OAJ08258.1 - 0.091 11.7 0.0 4.4 6.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 OAJ08258.1 - 0.093 12.8 0.1 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 OAJ08258.1 - 0.23 11.7 0.6 0.51 10.6 0.1 1.8 2 0 0 2 2 1 0 AAA domain DUF1352 PF07086.7 OAJ08258.1 - 3.1 7.4 7.2 5.3 6.6 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1352) Voltage_CLC PF00654.15 OAJ08262.1 - 2e-91 306.7 28.9 2e-91 306.7 20.0 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 OAJ08262.1 - 0.0002 21.0 0.0 0.00044 19.9 0.0 1.6 1 0 0 1 1 1 1 CBS domain Histone PF00125.19 OAJ08265.1 - 8.8e-30 102.6 0.4 1.4e-29 101.9 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ08265.1 - 1.3e-05 25.2 0.0 2.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAJ08265.1 - 0.008 16.2 0.2 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 OAJ08265.1 - 0.008 15.4 0.0 0.008 15.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T HEAT_PBS PF03130.11 OAJ08267.1 - 0.28 11.7 2.2 5.3 7.7 0.0 2.4 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Pkinase PF00069.20 OAJ08268.1 - 1.3e-64 217.8 0.0 1.5e-64 217.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ08268.1 - 4.4e-38 130.8 0.0 5.6e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ08268.1 - 1.9e-11 43.4 0.0 2.9e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 OAJ08268.1 - 0.0039 16.2 0.0 0.0083 15.2 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ08268.1 - 0.034 13.8 1.8 0.17 11.6 1.2 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family SDH_beta PF03315.10 OAJ08268.1 - 0.52 10.3 3.7 0.86 9.6 2.6 1.4 1 1 0 1 1 1 0 Serine dehydratase beta chain Zip PF02535.17 OAJ08273.1 - 1.4e-51 175.4 9.0 1.7e-51 175.1 6.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter YchF-GTPase_C PF06071.8 OAJ08274.1 - 9.1e-35 118.3 0.1 2.4e-34 116.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 OAJ08274.1 - 1.8e-13 50.4 0.0 5.2e-13 48.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ08274.1 - 8.9e-06 25.0 0.0 1.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Glyco_transf_20 PF00982.16 OAJ08278.1 - 2.8e-54 184.3 0.0 1.2e-46 159.1 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Serglycin PF04360.7 OAJ08278.1 - 0.35 10.6 11.1 0.081 12.6 3.8 2.3 2 0 0 2 2 2 0 Serglycin DUF677 PF05055.7 OAJ08279.1 - 0.061 11.9 0.1 0.065 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Glyco_tran_28_C PF04101.11 OAJ08281.1 - 9.5e-17 61.1 0.0 1.1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 OAJ08281.1 - 0.03 13.5 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1918 PF08940.6 OAJ08281.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Hydantoinase_A PF01968.13 OAJ08282.1 - 8e-68 228.6 0.4 1.5e-67 227.7 0.1 1.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase DUF3053 PF11254.3 OAJ08283.1 - 0.029 13.6 0.2 0.045 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) DUF3169 PF11368.3 OAJ08283.1 - 0.81 8.8 1.8 0.87 8.7 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) FRQ PF09421.5 OAJ08283.1 - 4.1 5.0 7.3 6.3 4.4 5.1 1.2 1 0 0 1 1 1 0 Frequency clock protein TPR_12 PF13424.1 OAJ08290.1 - 2.1e-17 62.8 26.2 3.9e-06 26.7 0.2 6.2 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ08290.1 - 1.5e-12 46.9 22.2 0.00094 19.0 0.2 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ08290.1 - 0.00013 21.5 15.8 1.5 8.5 0.3 6.1 5 3 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 OAJ08290.1 - 0.00017 21.2 17.1 15 5.7 0.0 7.6 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ08290.1 - 0.00035 20.9 19.8 22 6.0 0.0 7.8 5 2 2 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ08290.1 - 0.0028 17.3 1.0 1.1 9.1 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat T2SF PF00482.18 OAJ08290.1 - 0.056 13.3 8.6 4.8 7.1 0.8 4.1 1 1 3 4 4 4 0 Type II secretion system (T2SS), protein F TPR_4 PF07721.9 OAJ08290.1 - 0.4 11.2 12.7 9.5 6.9 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc5 PF12862.2 OAJ08290.1 - 0.53 10.1 11.5 2 8.3 0.4 5.4 2 2 3 5 5 5 0 Anaphase-promoting complex subunit 5 SPOR PF05036.8 OAJ08290.1 - 1.3 9.1 4.7 0.82 9.8 0.2 2.9 3 0 0 3 3 3 0 Sporulation related domain PQ-loop PF04193.9 OAJ08291.1 - 8.2e-27 92.5 11.5 1.8e-15 56.2 0.8 2.8 3 0 0 3 3 3 2 PQ loop repeat PLDc_N PF13396.1 OAJ08291.1 - 0.0096 15.5 0.1 0.0096 15.5 0.1 2.3 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal DUF4245 PF14030.1 OAJ08291.1 - 0.16 11.6 0.6 4.7 6.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) Pkinase PF00069.20 OAJ08299.1 - 1.5e-17 63.6 0.0 2e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ08299.1 - 3.5e-11 42.6 0.0 4.7e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ08299.1 - 3.5e-05 22.9 0.1 5e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Kinase-like MULE PF10551.4 OAJ08302.1 - 9.5e-10 38.5 0.1 2.5e-08 33.9 0.1 2.5 1 1 0 1 1 1 1 MULE transposase domain E7 PF00527.13 OAJ08302.1 - 0.14 12.3 3.0 9.3 6.4 0.0 3.1 3 0 0 3 3 3 0 E7 protein, Early protein Nop14 PF04147.7 OAJ08302.1 - 0.59 7.9 4.2 0.79 7.5 2.9 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_60s PF00428.14 OAJ08302.1 - 2.5 8.5 10.1 7 7.1 3.9 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPR_12 PF13424.1 OAJ08306.1 - 0.0008 19.3 24.5 2.3 8.2 0.0 7.6 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ08306.1 - 0.098 12.3 11.3 5.5 6.7 0.0 5.8 4 2 3 7 7 7 0 TPR repeat TPR_2 PF07719.12 OAJ08306.1 - 4 7.5 16.8 7.4 6.7 0.0 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat AMP-binding PF00501.23 OAJ08314.1 - 2.5e-81 273.2 0.0 2.9e-81 272.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ08314.1 - 4.6e-12 46.6 0.1 9.2e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain cwf21 PF08312.7 OAJ08315.1 - 4.4e-16 58.4 3.5 4.4e-16 58.4 2.4 2.7 2 1 0 2 2 2 1 cwf21 domain FGGY_C PF02782.11 OAJ08319.1 - 1.6e-09 37.6 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MFS_1 PF07690.11 OAJ08320.1 - 1.6e-32 112.6 63.1 4.9e-24 84.6 23.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1028 PF06267.7 OAJ08321.1 - 0.0045 16.4 0.0 0.0046 16.4 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF1028) Aminotran_5 PF00266.14 OAJ08322.1 - 1e-34 119.9 0.0 2e-34 118.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 OAJ08322.1 - 0.00018 20.5 0.0 0.0032 16.4 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 OAJ08322.1 - 0.027 13.5 0.1 0.062 12.3 0.1 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family EamA PF00892.15 OAJ08323.1 - 2.9e-26 91.9 44.9 2.5e-14 53.4 9.7 2.8 1 1 2 3 3 3 2 EamA-like transporter family TPT PF03151.11 OAJ08323.1 - 0.00019 21.0 22.5 0.017 14.7 3.5 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 OAJ08323.1 - 0.059 13.5 41.9 0.065 13.4 8.1 4.0 1 1 3 4 4 4 0 Multidrug resistance efflux transporter RVT_1 PF00078.22 OAJ08326.1 - 2e-15 56.7 0.0 3.5e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08326.1 - 8.9e-13 48.4 0.0 1.9e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ08326.1 - 0.00069 20.0 0.0 0.0017 18.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ08326.1 - 0.02 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease TFIIS_M PF07500.9 OAJ08328.1 - 9.9e-23 80.4 1.6 1.6e-22 79.7 0.1 2.0 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 OAJ08328.1 - 7e-19 67.1 7.8 1.2e-18 66.4 5.4 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 OAJ08328.1 - 1.6e-15 56.3 0.4 1.6e-15 56.3 0.3 1.7 2 0 0 2 2 2 1 TFIIS helical bundle-like domain TF_Zn_Ribbon PF08271.7 OAJ08328.1 - 0.014 14.6 0.5 0.025 13.8 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 OAJ08328.1 - 0.73 9.4 4.7 0.3 10.7 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 OAJ08328.1 - 1.2 8.8 4.8 0.54 10.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain AMP-binding PF00501.23 OAJ08329.1 - 2.5e-67 227.1 0.0 3.1e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ08329.1 - 2.8e-10 40.9 0.0 7.8e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Coatomer_E PF04733.9 OAJ08332.1 - 6e-44 150.3 8.2 7.6e-44 150.0 5.7 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 OAJ08332.1 - 8.3e-05 22.8 24.4 0.00084 19.6 2.8 4.3 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ08332.1 - 0.00036 20.1 0.3 0.00036 20.1 0.2 3.6 3 1 2 5 5 5 1 TPR repeat TPR_2 PF07719.12 OAJ08332.1 - 1 9.4 0.1 1 9.4 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ08332.1 - 4.9 8.0 25.3 0.61 10.8 2.1 5.5 3 2 3 6 6 6 0 Tetratricopeptide repeat tRNA-synt_1 PF00133.17 OAJ08333.1 - 3.7e-154 514.0 0.0 5.1e-154 513.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 OAJ08333.1 - 2e-24 86.1 0.0 4e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 OAJ08333.1 - 7.5e-21 74.2 0.3 4.7e-11 41.9 0.0 4.1 4 0 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 OAJ08333.1 - 0.0041 16.4 0.0 0.0071 15.6 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 OAJ08333.1 - 0.015 14.4 0.0 0.9 8.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.20 OAJ08337.1 - 4.5e-48 163.6 0.0 1.1e-46 159.0 0.0 2.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ08337.1 - 3.5e-26 91.8 0.0 1.1e-25 90.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ08337.1 - 0.00028 20.6 0.0 0.00028 20.6 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Med15 PF09606.5 OAJ08337.1 - 0.044 12.0 27.7 0.086 11.0 19.2 1.5 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pinin_SDK_memA PF04696.8 OAJ08337.1 - 0.11 12.1 12.2 0.31 10.6 7.9 2.1 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region YrbL-PhoP_reg PF10707.4 OAJ08337.1 - 0.22 10.8 0.0 0.22 10.8 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Ycf1 PF05758.7 OAJ08337.1 - 5.3 4.6 6.1 7.3 4.1 4.3 1.1 1 0 0 1 1 1 0 Ycf1 KAAG1 PF15354.1 OAJ08342.1 - 3.8 7.9 5.2 8.5 6.7 0.3 2.6 1 1 1 2 2 2 0 Kidney-associated antigen 1 DUF866 PF05907.8 OAJ08347.1 - 4e-38 130.4 0.3 5.1e-38 130.0 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF1272 PF06906.6 OAJ08347.1 - 0.012 15.4 2.1 0.06 13.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Cytochrome_C7 PF14522.1 OAJ08347.1 - 0.061 12.9 1.2 0.13 11.8 0.8 1.5 1 0 0 1 1 1 0 Cytochrome c7 Lar_restr_allev PF14354.1 OAJ08347.1 - 0.69 10.2 7.2 1.7 9.0 0.3 2.7 1 1 1 2 2 2 0 Restriction alleviation protein Lar OPT PF03169.10 OAJ08353.1 - 3.1e-160 534.6 51.5 4e-160 534.2 35.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4083 PF13314.1 OAJ08353.1 - 0.13 12.0 0.2 0.37 10.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) FUN14 PF04930.10 OAJ08358.1 - 1.9e-20 72.9 0.7 3.4e-20 72.2 0.5 1.4 1 0 0 1 1 1 1 FUN14 family Actin PF00022.14 OAJ08359.1 - 6e-97 324.5 0.0 6.8e-97 324.3 0.0 1.0 1 0 0 1 1 1 1 Actin Methyltransf_29 PF03141.11 OAJ08359.1 - 0.013 13.8 0.0 0.018 13.4 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ESSS PF10183.4 OAJ08359.1 - 0.037 14.4 0.0 0.09 13.1 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) p450 PF00067.17 OAJ08360.1 - 2.2e-72 244.0 0.0 2.9e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DEAD PF00270.24 OAJ08363.1 - 7.5e-37 126.4 0.3 2.3e-36 124.8 0.2 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ08363.1 - 7.6e-19 67.3 0.0 2e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 OAJ08363.1 - 3.5e-14 52.0 0.0 7.1e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 OAJ08363.1 - 4.5e-06 26.6 0.0 2.6e-05 24.1 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4137 PF13593.1 OAJ08363.1 - 0.0068 15.5 0.1 0.01 14.9 0.1 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) AAA_22 PF13401.1 OAJ08363.1 - 0.036 14.2 1.2 0.47 10.5 0.9 2.4 1 1 0 1 1 1 0 AAA domain SR-25 PF10500.4 OAJ08363.1 - 0.44 9.9 20.1 0.023 14.1 9.7 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.7 OAJ08363.1 - 2.4 7.7 21.0 2 8.0 10.3 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Tombus_P33 PF08500.5 OAJ08363.1 - 6.3 6.5 7.3 14 5.4 4.6 1.8 1 1 0 1 1 1 0 Tombusvirus p33 CDC45 PF02724.9 OAJ08363.1 - 6.5 4.6 15.4 12 3.8 10.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Mito_fiss_reg PF05308.6 OAJ08364.1 - 0.94 8.7 3.3 1 8.6 2.3 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator Omega-toxin PF06357.6 OAJ08364.1 - 1.5 8.4 5.7 0.11 12.0 0.6 1.8 2 0 0 2 2 2 0 Omega-atracotoxin EB PF01683.13 OAJ08364.1 - 2.4 8.3 7.0 11 6.1 5.4 1.6 1 1 1 2 2 2 0 EB module SSP160 PF06933.6 OAJ08364.1 - 3.5 5.4 17.6 4 5.2 12.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 OAJ08364.1 - 5.2 4.6 6.8 4.9 4.7 4.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RAP1 PF07218.6 OAJ08365.1 - 0.024 12.7 14.4 0.029 12.4 10.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Hamartin PF04388.7 OAJ08365.1 - 0.28 9.8 19.8 0.26 9.8 13.7 1.0 1 0 0 1 1 1 0 Hamartin protein DUF605 PF04652.11 OAJ08365.1 - 0.41 10.0 17.5 0.45 9.8 12.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF566 PF04484.7 OAJ08365.1 - 1.2 8.5 19.2 1.3 8.4 13.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Pol_alpha_B_N PF08418.5 OAJ08365.1 - 8.9 5.7 23.3 14 5.1 16.2 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RVT_1 PF00078.22 OAJ08367.1 - 5.3e-18 65.1 0.0 1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08367.1 - 1.2e-15 57.6 0.0 2.2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Phospholip_B PF04916.8 OAJ08367.1 - 0.21 9.6 0.0 0.32 9.0 0.0 1.1 1 0 0 1 1 1 0 Phospholipase B ABC2_membrane_3 PF12698.2 OAJ08370.1 - 0.057 12.4 3.8 0.1 11.5 2.6 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Suf PF05843.9 OAJ08370.1 - 0.07 12.8 9.2 0.12 12.0 6.4 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF572 PF04502.8 OAJ08370.1 - 0.58 9.3 6.9 1.1 8.3 4.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF605 PF04652.11 OAJ08370.1 - 7.7 5.8 24.5 12 5.1 17.0 1.3 1 0 0 1 1 1 0 Vta1 like Na_H_Exchanger PF00999.16 OAJ08374.1 - 0.0018 16.9 0.3 0.0024 16.4 0.2 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MannoseP_isomer PF01050.13 OAJ08384.1 - 2.5e-07 30.4 0.1 3.2e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Dus PF01207.12 OAJ08385.1 - 6.4e-63 212.4 0.0 1.2e-61 208.3 0.0 2.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TPR_11 PF13414.1 OAJ08385.1 - 5.7e-10 38.6 2.8 0.00012 21.6 0.7 3.5 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 OAJ08385.1 - 1.9e-05 24.0 3.5 1.4 8.6 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ08385.1 - 0.003 18.1 6.2 0.28 11.8 0.0 4.0 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ08385.1 - 0.037 13.9 1.6 1.3 8.9 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat IL6 PF00489.12 OAJ08385.1 - 0.096 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family His_biosynth PF00977.16 OAJ08385.1 - 0.11 11.6 0.0 0.54 9.4 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein TPR_2 PF07719.12 OAJ08385.1 - 0.16 11.9 6.6 0.83 9.7 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat RVT_2 PF07727.9 OAJ08391.1 - 3.2e-85 285.0 0.0 4.5e-85 284.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08391.1 - 1.9e-21 76.3 0.0 3.4e-20 72.3 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ08391.1 - 2.5e-05 23.8 0.0 6.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 OAJ08392.1 - 1.2e-09 37.9 0.0 2.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAJ08392.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ08392.1 - 0.12 12.3 3.6 0.21 11.5 2.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-H2C2_2 PF13465.1 OAJ08394.1 - 0.00035 20.7 2.4 0.0018 18.4 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ08394.1 - 0.0016 18.6 2.5 0.0016 18.6 1.7 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ08394.1 - 1.9 9.0 6.0 0.37 11.2 0.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger IF-2B PF01008.12 OAJ08397.1 - 9.5e-67 224.9 0.0 1.2e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family MmgE_PrpD PF03972.9 OAJ08398.1 - 4.3e-71 239.4 0.2 5.8e-37 126.9 0.0 2.0 1 1 1 2 2 2 2 MmgE/PrpD family MmgE_PrpD PF03972.9 OAJ08399.1 - 3.2e-12 45.3 0.0 3.5e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family RVT_2 PF07727.9 OAJ08404.1 - 1.7e-79 266.2 0.0 2.7e-79 265.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08404.1 - 3.4e-23 82.0 0.0 8.7e-23 80.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ08404.1 - 6.4e-05 22.4 0.1 0.00037 19.9 0.1 2.2 1 1 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ08404.1 - 0.00063 19.3 0.1 0.0014 18.1 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 OAJ08405.1 - 0.0001 22.0 5.0 0.00021 21.0 3.5 1.5 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 OAJ08405.1 - 0.0014 18.3 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.1 OAJ08405.1 - 0.026 14.0 0.8 0.047 13.1 0.5 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ08405.1 - 0.038 13.7 1.5 0.069 12.8 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF455 PF04305.9 OAJ08408.1 - 5e-93 311.0 0.0 6.6e-93 310.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 OAJ08408.1 - 3.5e-08 32.8 1.5 1.3e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 OAJ08408.1 - 0.0012 18.5 0.0 0.0033 17.1 0.0 1.7 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain Amidase PF01425.16 OAJ08409.1 - 2.4e-89 300.2 0.0 7.8e-89 298.5 0.0 1.8 2 0 0 2 2 2 1 Amidase DUF4449 PF14613.1 OAJ08413.1 - 5.8e-26 91.3 1.3 5.8e-26 91.3 0.9 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Phage_connect_1 PF05135.8 OAJ08413.1 - 5.4 7.2 7.1 21 5.3 0.2 3.2 3 0 0 3 3 3 0 Phage gp6-like head-tail connector protein NT-C2 PF10358.4 OAJ08417.1 - 9.8e-12 44.5 0.0 1.9e-05 24.1 0.0 3.1 2 1 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins Nucleoplasmin PF03066.10 OAJ08417.1 - 7 6.1 11.4 19 4.7 7.9 1.7 1 0 0 1 1 1 0 Nucleoplasmin MDM31_MDM32 PF08118.6 OAJ08422.1 - 1.8e-121 406.0 2.0 4.1e-56 190.4 0.0 3.1 2 1 0 3 3 3 3 Yeast mitochondrial distribution and morphology (MDM) proteins ATP-sulfurylase PF01747.12 OAJ08430.1 - 3.1e-87 291.4 0.6 4.4e-87 290.9 0.4 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 OAJ08430.1 - 9.8e-54 181.2 0.0 1.6e-53 180.5 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 OAJ08430.1 - 4.1e-51 172.5 0.0 7e-51 171.8 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain GIT_SHD PF08518.6 OAJ08433.1 - 2e-24 84.6 8.7 1.6e-14 52.9 0.8 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF3584 PF12128.3 OAJ08433.1 - 0.12 9.7 24.1 0.25 8.6 16.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 OAJ08433.1 - 0.3 9.4 19.2 0.97 7.8 13.3 1.7 1 1 0 1 1 1 0 AAA domain APG6 PF04111.7 OAJ08433.1 - 3.1 6.7 33.1 0.068 12.1 11.7 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 FKBP_C PF00254.23 OAJ08434.1 - 3e-34 116.9 0.3 9.1e-33 112.1 0.0 2.3 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Apolipoprotein PF01442.13 OAJ08434.1 - 0.00011 21.7 8.7 0.00014 21.4 6.0 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Phasin_2 PF09361.5 OAJ08434.1 - 0.0011 19.0 14.2 0.0011 19.0 9.8 1.7 1 1 0 1 1 1 1 Phasin protein DUF883 PF05957.8 OAJ08434.1 - 0.1 13.0 14.0 0.29 11.5 4.4 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.6 OAJ08434.1 - 0.3 8.5 5.3 0.38 8.2 3.7 1.1 1 0 0 1 1 1 0 Prominin YtxH PF12732.2 OAJ08434.1 - 0.43 10.9 16.9 7.7e+02 0.5 11.4 3.1 2 1 0 2 2 2 0 YtxH-like protein HisKA_3 PF07730.8 OAJ08434.1 - 1 9.7 4.6 38 4.7 3.2 2.9 1 1 0 1 1 1 0 Histidine kinase AF0941-like PF14591.1 OAJ08434.1 - 1.1 9.3 6.2 1.9 8.5 4.3 1.4 1 0 0 1 1 1 0 AF0941-like Borrelia_P83 PF05262.6 OAJ08434.1 - 2.2 6.4 15.6 3.4 5.8 10.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Cytochrom_C_2 PF01322.15 OAJ08434.1 - 4.7 7.7 12.6 10 6.6 8.7 1.6 1 1 0 1 1 1 0 Cytochrome C' RVT_1 PF00078.22 OAJ08446.1 - 7.5e-16 58.1 0.0 1.4e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ08446.1 - 0.013 15.9 0.1 0.055 13.9 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease HEAT_EZ PF13513.1 OAJ08449.1 - 6.7e-06 26.4 5.1 0.0041 17.5 0.2 3.0 1 1 2 3 3 3 3 HEAT-like repeat HEAT_2 PF13646.1 OAJ08449.1 - 0.00024 21.3 3.6 0.061 13.6 0.2 2.5 1 1 2 3 3 3 3 HEAT repeats HEAT PF02985.17 OAJ08449.1 - 0.0012 18.7 8.2 0.0057 16.6 0.1 4.1 4 1 1 5 5 5 1 HEAT repeat DUF1546 PF07571.8 OAJ08449.1 - 0.021 14.9 0.4 0.041 13.9 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1546) DUF2363 PF10155.4 OAJ08449.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2363) MDMPI_N PF11716.3 OAJ08449.1 - 0.45 10.9 3.8 0.65 10.4 2.6 1.3 1 1 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain HEAT_PBS PF03130.11 OAJ08449.1 - 6.9 7.4 7.7 24 5.7 0.4 3.0 2 1 0 2 2 2 0 PBS lyase HEAT-like repeat SAMP PF05924.6 OAJ08449.1 - 8.1 5.7 6.0 14 4.9 0.9 2.5 2 0 0 2 2 2 0 SAMP Motif PAPA-1 PF04795.7 OAJ08454.1 - 5.4e-15 55.8 15.7 1e-13 51.7 5.7 3.7 2 1 0 2 2 2 1 PAPA-1-like conserved region Daxx PF03344.10 OAJ08454.1 - 0.0027 16.2 32.1 0.0027 16.2 22.3 2.1 2 0 0 2 2 2 2 Daxx Family Mito_carr PF00153.22 OAJ08455.1 - 2.3e-53 177.8 5.2 2.2e-17 62.5 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.2 OAJ08455.1 - 1.8 8.9 5.2 0.2 12.0 0.2 2.0 2 0 0 2 2 2 0 YtxH-like protein UvrD_C_2 PF13538.1 OAJ08458.1 - 0.0062 16.6 0.1 0.013 15.6 0.1 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain MFS_1 PF07690.11 OAJ08462.1 - 3.3e-12 45.7 23.5 3.8e-12 45.6 16.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Nop53 PF07767.6 OAJ08466.1 - 1.9e-14 53.4 0.3 2.2e-14 53.2 0.2 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CPSase_sm_chain PF00988.17 OAJ08467.1 - 5.1e-44 148.9 0.0 7.8e-44 148.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 OAJ08467.1 - 5.3e-36 123.8 0.0 5.8e-35 120.4 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 OAJ08467.1 - 2.9e-05 23.6 0.2 0.00022 20.7 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 CASP_C PF08172.7 OAJ08468.1 - 1.6e-59 200.9 0.0 1.6e-59 200.9 0.0 4.0 2 2 0 2 2 2 1 CASP C terminal CtIP_N PF10482.4 OAJ08468.1 - 0.025 14.3 0.3 0.025 14.3 0.2 4.0 4 0 0 4 4 4 0 Tumour-suppressor protein CtIP N-terminal domain LOH1CR12 PF10158.4 OAJ08468.1 - 0.039 13.7 1.0 0.45 10.3 0.7 2.7 2 0 0 2 2 2 0 Tumour suppressor protein FlaC_arch PF05377.6 OAJ08468.1 - 0.048 13.5 10.7 5.1 7.0 0.1 5.5 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Mnd1 PF03962.10 OAJ08468.1 - 3.3 7.3 34.6 1.2 8.7 0.3 5.3 3 1 2 5 5 5 0 Mnd1 family WD40_alt PF14077.1 OAJ08468.1 - 7.8 6.2 7.4 1.1 8.9 0.3 3.0 3 0 0 3 3 3 0 Alternative WD40 repeat motif Phosducin PF02114.11 OAJ08472.1 - 6.7e-09 34.8 0.2 1.5e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 Phosducin Apc9 PF12856.2 OAJ08472.1 - 0.36 10.9 3.7 0.57 10.2 0.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 9 PBP1_TM PF14812.1 OAJ08472.1 - 0.65 10.3 14.1 0.63 10.3 5.6 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 OAJ08472.1 - 2.1 7.8 6.3 1.1 8.7 1.5 2.2 2 0 0 2 2 2 0 Nucleoplasmin Sporozoite_P67 PF05642.6 OAJ08472.1 - 3.3 5.4 5.8 3.7 5.2 0.1 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen TPR_11 PF13414.1 OAJ08473.1 - 2.6e-10 39.7 8.8 2e-09 36.9 0.8 3.2 3 0 0 3 3 3 2 TPR repeat DnaJ PF00226.26 OAJ08473.1 - 7.5e-06 25.6 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.23 OAJ08473.1 - 0.0027 17.2 1.1 0.025 14.1 0.8 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ08473.1 - 0.28 11.2 14.0 0.027 14.3 1.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat BAF1_ABF1 PF04684.8 OAJ08473.1 - 0.47 9.2 8.6 0.76 8.5 6.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GATA PF00320.22 OAJ08477.1 - 4.4e-17 61.1 4.6 1e-16 59.9 3.2 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 OAJ08477.1 - 9.5e-14 50.6 2.0 1.7e-13 49.8 1.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) F-box-like PF12937.2 OAJ08479.1 - 0.0011 18.6 0.6 0.0023 17.5 0.4 1.6 1 0 0 1 1 1 1 F-box-like RVT_1 PF00078.22 OAJ08486.1 - 8.8e-15 54.6 0.0 2e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08486.1 - 9.9e-12 45.0 0.2 4.3e-11 42.9 0.1 2.1 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 OAJ08486.1 - 0.005 16.7 2.5 0.005 16.7 1.7 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ08486.1 - 0.03 13.8 0.8 0.062 12.8 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ08486.1 - 0.23 11.1 2.6 3 7.5 1.4 2.7 2 0 0 2 2 2 0 Zinc knuckle Tropomyosin PF00261.15 OAJ08491.1 - 0.018 14.1 1.5 0.031 13.3 1.0 1.3 1 0 0 1 1 1 0 Tropomyosin DUF241 PF03087.9 OAJ08491.1 - 0.095 12.1 5.5 0.077 12.4 2.2 1.9 2 1 0 3 3 3 0 Arabidopsis protein of unknown function Cytochrom_B562 PF07361.6 OAJ08491.1 - 0.13 12.6 2.8 0.87 10.0 0.1 2.3 2 0 0 2 2 2 0 Cytochrome b562 DUF2703 PF10865.3 OAJ08491.1 - 0.2 11.5 3.3 1.6 8.6 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) Peptidase_S10 PF00450.17 OAJ08492.1 - 6.4e-91 305.5 0.0 6.3e-79 266.0 0.0 2.5 2 1 0 2 2 2 2 Serine carboxypeptidase Sin3_corepress PF08295.7 OAJ08492.1 - 0.21 11.3 0.3 1.7 8.4 0.0 2.4 3 0 0 3 3 3 0 Sin3 family co-repressor Ank PF00023.25 OAJ08498.1 - 3.4e-12 45.5 0.9 6.4e-06 25.7 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 OAJ08498.1 - 3.9e-11 42.0 0.3 0.00034 20.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 OAJ08498.1 - 4.1e-11 43.0 3.2 1.3e-09 38.2 2.2 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ08498.1 - 4.6e-11 42.9 1.2 4.9e-08 33.2 0.2 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ08498.1 - 1.7e-09 37.5 2.2 0.00011 22.3 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) SPT16 PF08644.6 OAJ08498.1 - 0.054 13.3 0.1 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Rtf2 PF04641.7 OAJ08498.1 - 6.4 5.8 10.4 0.38 9.9 2.3 2.2 2 1 0 2 2 2 0 Rtf2 RING-finger Prenyltrans_2 PF13249.1 OAJ08499.1 - 1.1e-43 148.2 0.6 1.6e-13 51.0 0.2 4.9 2 2 4 6 6 6 6 Prenyltransferase-like Prenyltrans PF00432.16 OAJ08499.1 - 2e-30 104.0 10.5 2.8e-08 33.1 0.0 7.4 8 0 0 8 8 8 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 OAJ08499.1 - 2.8e-29 101.3 0.6 2.1e-12 47.0 0.1 6.3 3 3 4 7 7 7 5 Prenyltransferase-like Pec_lyase PF09492.5 OAJ08499.1 - 1.8e-08 33.8 0.0 0.042 13.0 0.0 4.5 1 1 3 5 5 5 3 Pectic acid lyase A2M_comp PF07678.9 OAJ08499.1 - 1.1e-05 24.7 0.1 0.014 14.6 0.0 3.9 2 1 2 4 4 4 2 A-macroglobulin complement component NTR2 PF15458.1 OAJ08500.1 - 0.019 14.2 0.3 0.023 13.9 0.2 1.1 1 0 0 1 1 1 0 Nineteen complex-related protein 2 SPT2 PF08243.6 OAJ08500.1 - 0.15 12.3 1.4 0.18 12.1 1.0 1.5 1 1 0 1 1 1 0 SPT2 chromatin protein FAM92 PF06730.6 OAJ08501.1 - 0.031 13.6 0.2 0.037 13.3 0.1 1.1 1 0 0 1 1 1 0 FAM92 protein Tropomyosin_1 PF12718.2 OAJ08501.1 - 0.036 13.9 2.8 0.066 13.0 2.0 1.4 1 1 0 1 1 1 0 Tropomyosin like Tropomyosin PF00261.15 OAJ08501.1 - 0.037 13.1 0.9 0.046 12.8 0.6 1.1 1 0 0 1 1 1 0 Tropomyosin ERp29 PF07749.7 OAJ08501.1 - 0.073 13.7 0.2 0.15 12.6 0.1 1.6 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF3560 PF12083.3 OAJ08501.1 - 0.087 12.8 1.4 0.1 12.6 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) CwfJ_C_1 PF04677.10 OAJ08506.1 - 1.8e-26 92.1 0.0 2.5e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 OAJ08506.1 - 1.7e-22 79.7 0.1 3.5e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 WD40 PF00400.27 OAJ08510.1 - 5e-15 54.7 5.8 1.8e-06 27.6 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat USP7_ICP0_bdg PF12436.3 OAJ08515.1 - 7.1e-81 271.1 0.0 2.1e-80 269.5 0.0 1.9 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 OAJ08515.1 - 1.3e-64 217.5 0.8 7.3e-63 211.8 0.3 2.9 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 OAJ08515.1 - 1.6e-54 184.8 0.1 4.4e-54 183.3 0.0 1.8 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ08515.1 - 3.1e-31 108.9 0.0 6.2e-31 107.9 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 OAJ08515.1 - 3.5e-08 33.7 0.3 8.3e-07 29.2 0.0 3.2 2 1 0 2 2 2 1 MATH domain FF PF01846.14 OAJ08517.1 - 4.9e-17 61.6 14.7 1.1e-07 31.6 0.2 4.9 4 1 0 4 4 4 4 FF domain Glyco_trans_4_3 PF12000.3 OAJ08517.1 - 0.042 13.4 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Gkycosyl transferase family 4 group DUF3391 PF11871.3 OAJ08517.1 - 3.4 7.8 13.0 14 5.8 4.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) Oxysterol_BP PF01237.13 OAJ08518.1 - 1.3e-110 369.2 0.3 3.2e-110 367.9 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 OAJ08518.1 - 4e-16 58.8 0.0 7.7e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 OAJ08518.1 - 0.00013 22.1 0.0 0.00031 20.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 OAJ08518.1 - 0.01 16.0 0.7 0.039 14.1 0.5 1.9 1 1 1 2 2 2 0 Pleckstrin homology domain PPR_2 PF13041.1 OAJ08523.1 - 0.13 12.2 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 PPR repeat family APH PF01636.18 OAJ08524.1 - 1.6e-17 64.0 0.0 2.9e-17 63.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family CDC37_M PF08565.6 OAJ08524.1 - 0.16 11.4 0.1 0.24 10.8 0.1 1.2 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain zf-RING_UBOX PF13445.1 OAJ08528.1 - 3.2e-16 58.7 0.3 7.2e-16 57.6 0.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 OAJ08528.1 - 1.8e-11 43.9 0.0 3.7e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_5 PF14634.1 OAJ08528.1 - 5.7e-05 22.7 0.7 0.00012 21.7 0.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 OAJ08528.1 - 9.8e-05 22.1 0.7 0.00022 20.9 0.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ08528.1 - 0.00015 21.6 1.1 0.0003 20.7 0.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAJ08528.1 - 0.00024 20.9 0.4 0.00054 19.7 0.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 OAJ08528.1 - 0.00027 20.5 0.6 0.00049 19.7 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 OAJ08528.1 - 0.0025 17.0 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 OAJ08528.1 - 0.0034 16.9 0.9 0.0072 15.9 0.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PilJ PF13675.1 OAJ08528.1 - 0.086 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Sigma70_ner PF04546.8 OAJ08537.1 - 0.96 9.0 9.0 0.1 12.2 2.1 2.5 3 0 0 3 3 3 0 Sigma-70, non-essential region Pox_Ag35 PF03286.9 OAJ08539.1 - 0.033 13.7 3.2 0.061 12.8 2.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ICAP-1_inte_bdg PF10480.4 OAJ08539.1 - 1.5 8.5 8.5 2.2 8.0 5.9 1.2 1 0 0 1 1 1 0 Beta-1 integrin binding protein DUF1967 PF09269.6 OAJ08545.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Sec1 PF00995.18 OAJ08546.1 - 1.2e-08 34.0 0.0 1.5e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family ResB PF05140.9 OAJ08547.1 - 0.2 10.1 1.7 0.28 9.7 1.2 1.2 1 0 0 1 1 1 0 ResB-like family DUF1443 PF07280.6 OAJ08547.1 - 3.8 7.1 6.6 6.5 6.4 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1443) Mito_carr PF00153.22 OAJ08551.1 - 9.5e-11 41.2 1.4 0.00027 20.5 0.0 4.1 4 0 0 4 4 4 2 Mitochondrial carrier protein PRA1 PF03208.14 OAJ08551.1 - 0.4 10.0 3.2 15 4.8 0.0 2.6 2 0 0 2 2 2 0 PRA1 family protein FHA PF00498.21 OAJ08552.1 - 0.026 14.6 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 FHA domain Transposase_21 PF02992.9 OAJ08557.1 - 4.9e-19 68.3 0.0 7.5e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ08557.1 - 0.00033 20.0 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) NOC3p PF07540.6 OAJ08562.1 - 8.8e-22 77.1 0.2 9.3e-18 64.3 0.0 3.0 3 0 0 3 3 3 2 Nucleolar complex-associated protein CBF PF03914.12 OAJ08562.1 - 1.1e-17 63.9 0.0 1.1e-17 63.9 0.0 4.3 4 2 1 5 5 5 1 CBF/Mak21 family FHA PF00498.21 OAJ08573.1 - 0.052 13.6 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 FHA domain Glyoxal_oxid_N PF07250.6 OAJ08581.1 - 5.6e-26 91.0 0.0 2.2e-23 82.5 0.0 3.7 3 1 0 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 OAJ08581.1 - 4.1e-20 71.7 0.2 8.2e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) SKG6 PF08693.5 OAJ08581.1 - 0.27 10.5 0.7 0.53 9.6 0.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain UCR_Fe-S_N PF10399.4 OAJ08585.1 - 3.3 6.9 0.0 3.3 6.9 0.0 2.9 2 1 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Collagen PF01391.13 OAJ08590.1 - 2.3e-23 81.4 80.8 84 2.8 56.0 3.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) WD40 PF00400.27 OAJ08594.1 - 2e-25 87.6 3.0 2.7e-07 30.2 0.0 6.1 5 0 0 5 5 5 5 WD domain, G-beta repeat DUF1484 PF07363.6 OAJ08603.1 - 0.022 15.0 0.1 0.044 14.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) Med3 PF11593.3 OAJ08604.1 - 0.012 14.8 1.2 0.015 14.5 0.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Prefoldin PF02996.12 OAJ08604.1 - 0.028 14.0 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Prefoldin subunit Pkinase PF00069.20 OAJ08607.1 - 1.7e-43 148.6 0.0 2.2e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ08607.1 - 2.4e-26 92.3 0.0 3e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ08607.1 - 6.8e-08 31.8 0.0 1.3e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ08607.1 - 7e-07 29.2 0.1 1.5e-06 28.1 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family APH_6_hur PF04655.9 OAJ08607.1 - 0.03 13.4 0.1 0.068 12.3 0.0 1.6 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase PIN_4 PF13638.1 OAJ08610.1 - 5e-21 75.2 0.0 3.1e-20 72.6 0.0 2.2 1 1 0 1 1 1 1 PIN domain TMCO5 PF14992.1 OAJ08612.1 - 0.21 10.6 4.0 0.25 10.4 2.8 1.0 1 0 0 1 1 1 0 TMCO5 family TIR_2 PF13676.1 OAJ08612.1 - 0.56 10.3 7.1 0.53 10.4 3.4 1.8 1 1 1 2 2 2 0 TIR domain CBF_beta PF02312.12 OAJ08617.1 - 0.081 12.5 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Core binding factor beta subunit Med26 PF08711.6 OAJ08618.1 - 4.5e-06 26.0 0.0 9.2e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DNA_Packaging PF11053.3 OAJ08618.1 - 0.022 14.3 0.3 0.026 14.1 0.2 1.1 1 0 0 1 1 1 0 Terminase DNA packaging enzyme HAT PF02184.11 OAJ08618.1 - 0.023 14.4 0.2 0.048 13.4 0.1 1.5 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat DUF3381 PF11861.3 OAJ08618.1 - 0.15 11.5 2.8 0.18 11.2 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) RVT_1 PF00078.22 OAJ08625.1 - 2.4e-18 66.2 0.0 4.7e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08625.1 - 8.5e-15 54.9 0.0 1.7e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Prok-JAB PF14464.1 OAJ08630.1 - 0.043 13.3 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain BSP_II PF05432.6 OAJ08630.1 - 1.2 8.3 11.2 1.9 7.6 7.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Peptidase_C48 PF02902.14 OAJ08631.1 - 3.2e-11 43.2 0.0 5e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HsbA PF12296.3 OAJ08635.1 - 1.5e-12 47.4 6.8 1.5e-12 47.4 4.7 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DivIVA PF05103.8 OAJ08635.1 - 0.027 14.4 0.4 0.08 12.9 0.0 1.8 2 0 0 2 2 2 0 DivIVA protein RNase_PH PF01138.16 OAJ08640.1 - 1.6e-11 44.6 0.1 2.8e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Abhydrolase_3 PF07859.8 OAJ08643.1 - 6.9e-27 94.3 0.0 1.2e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAJ08643.1 - 1.8e-07 30.5 0.1 0.0017 17.5 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAJ08643.1 - 1.7e-05 24.5 0.3 5.3e-05 23.0 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAJ08643.1 - 0.00057 19.3 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Ribosomal_60s PF00428.14 OAJ08643.1 - 0.015 15.6 16.5 0.034 14.5 8.1 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glyco_transf_22 PF03901.12 OAJ08644.1 - 2e-27 96.2 9.3 2.4e-27 95.9 6.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Syntaxin-18_N PF10496.4 OAJ08645.1 - 1.6e-06 27.8 0.6 1.8e-05 24.4 0.0 2.9 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Motilin_assoc PF04643.7 OAJ08645.1 - 0.043 13.3 0.3 0.094 12.2 0.2 1.6 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide Ank_2 PF12796.2 OAJ08651.1 - 0.16 12.3 0.0 0.7 10.2 0.0 2.1 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) SR-25 PF10500.4 OAJ08651.1 - 7.8 5.8 9.2 6.9 6.0 1.1 2.9 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein SBF PF01758.11 OAJ08652.1 - 2.2e-39 134.8 15.6 2.2e-39 134.8 10.8 2.1 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF3169 PF11368.3 OAJ08652.1 - 0.027 13.6 0.4 0.027 13.6 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) RALF PF05498.6 OAJ08658.1 - 0.033 15.0 0.0 1.9 9.3 0.0 2.1 1 1 1 2 2 2 0 Rapid ALkalinization Factor (RALF) EFG_C PF00679.19 OAJ08662.1 - 0.1 12.5 0.0 4 7.3 0.0 2.3 1 1 1 2 2 2 0 Elongation factor G C-terminus DMP1 PF07263.6 OAJ08663.1 - 0.023 13.4 12.1 0.027 13.1 8.4 1.1 1 0 0 1 1 1 0 Dentin matrix protein 1 (DMP1) GalP_UDP_tr_C PF02744.12 OAJ08663.1 - 0.15 11.6 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain PBP1_TM PF14812.1 OAJ08663.1 - 0.29 11.4 2.7 0.52 10.6 1.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 OAJ08663.1 - 0.51 9.5 5.1 0.63 9.2 3.5 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 OAJ08663.1 - 0.59 9.6 4.7 1 8.8 3.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 OAJ08663.1 - 1.4 9.1 13.3 0.76 10.0 7.6 1.7 1 1 1 2 2 2 0 Centromere protein B dimerisation domain Phage_integrase PF00589.17 OAJ08669.1 - 4e-05 23.3 0.1 9.1e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 OAJ08669.1 - 0.076 12.3 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) His_Phos_1 PF00300.17 OAJ08672.1 - 0.029 14.4 0.1 0.076 13.1 0.0 1.7 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) HMGL-like PF00682.14 OAJ08673.1 - 9.9e-62 208.6 0.0 1.4e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 OAJ08673.1 - 3.2e-18 65.8 0.1 3.5e-09 36.5 0.0 2.6 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain NAGLU PF05089.7 OAJ08677.1 - 0.058 12.1 0.1 0.092 11.4 0.1 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain DDE_3 PF13358.1 OAJ08678.1 - 6.1e-31 107.1 0.0 9.6e-31 106.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 OAJ08678.1 - 6e-08 32.8 0.0 1.3e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 OAJ08678.1 - 2.3e-07 31.5 0.0 7.2e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 OAJ08678.1 - 1.8e-06 27.8 0.2 0.00023 21.0 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.1 OAJ08678.1 - 0.00025 20.5 0.3 0.0017 17.8 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 OAJ08678.1 - 0.00035 20.5 0.0 0.0019 18.2 0.0 2.2 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 OAJ08678.1 - 0.00054 19.5 0.0 0.044 13.4 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain DDE_1 PF03184.14 OAJ08678.1 - 0.0026 16.9 0.0 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 OAJ08678.1 - 0.0047 17.0 0.0 0.019 15.0 0.0 2.2 1 1 0 1 1 1 1 Integrase core domain PAX PF00292.13 OAJ08678.1 - 0.12 12.0 0.0 0.67 9.6 0.0 1.9 2 0 0 2 2 2 0 'Paired box' domain MFS_1 PF07690.11 OAJ08682.1 - 1.8e-14 53.2 53.7 6.1e-14 51.4 30.3 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily RVT_1 PF00078.22 OAJ08687.1 - 1.1e-21 77.2 0.0 2.5e-21 76.0 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Histone PF00125.19 OAJ08692.1 - 3.5e-20 71.9 0.1 5.3e-20 71.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Pyridoxal_deC PF00282.14 OAJ08696.1 - 2.5e-32 111.7 0.0 8.1e-31 106.7 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF3291 PF11695.3 OAJ08696.1 - 0.14 11.6 0.0 6.1 6.2 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3291) RVT_2 PF07727.9 OAJ08700.1 - 3.8e-25 88.2 0.0 5.4e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dak2 PF02734.12 OAJ08701.1 - 0.018 14.7 0.1 0.067 12.8 0.0 1.9 1 1 0 2 2 2 0 DAK2 domain DUF3008 PF11450.3 OAJ08701.1 - 0.065 13.3 0.2 3.9 7.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) MoaC PF01967.16 OAJ08701.1 - 0.086 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 MoaC family SPDY PF03771.11 OAJ08702.1 - 0.11 11.9 1.4 0.26 10.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF317) Asp PF00026.18 OAJ08706.1 - 1.4e-48 165.7 0.0 3.3e-48 164.5 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ08706.1 - 0.00014 21.8 2.7 0.00038 20.4 0.3 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal RVP PF00077.15 OAJ08706.1 - 0.14 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease SHR3_chaperone PF08229.6 OAJ08707.1 - 2e-30 105.2 2.1 8.1e-30 103.2 1.5 1.8 1 1 0 1 1 1 1 ER membrane protein SH3 DUF2269 PF10027.4 OAJ08707.1 - 0.07 12.9 3.2 0.28 10.9 0.7 2.4 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2269) Ras PF00071.17 OAJ08708.1 - 1.2e-15 57.2 0.0 1.5e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Ras family RRM_1 PF00076.17 OAJ08712.1 - 2.3e-23 81.5 0.0 3.5e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ08712.1 - 1.2e-18 66.7 0.0 1.7e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ08712.1 - 2.6e-11 43.1 0.0 3.8e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HsbA PF12296.3 OAJ08713.1 - 8e-14 51.5 13.5 1.3e-13 50.9 9.4 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Pox_A6 PF04924.7 OAJ08713.1 - 0.032 13.0 0.6 0.035 12.9 0.4 1.2 1 0 0 1 1 1 0 Poxvirus A6 protein FUN14 PF04930.10 OAJ08713.1 - 2.2 8.5 5.2 14 6.0 3.6 2.4 1 1 0 1 1 1 0 FUN14 family MULE PF10551.4 OAJ08715.1 - 6.7e-09 35.8 0.3 4.2e-08 33.2 0.1 2.4 3 0 0 3 3 3 1 MULE transposase domain SWIM PF04434.12 OAJ08715.1 - 0.00023 20.5 1.3 0.00069 19.0 0.9 1.8 1 0 0 1 1 1 1 SWIM zinc finger HbrB PF08539.6 OAJ08720.1 - 5.7e-20 71.7 0.0 2.9e-08 33.7 0.0 3.2 3 0 0 3 3 3 3 HbrB-like SDA1 PF05285.7 OAJ08721.1 - 0.031 13.5 16.7 0.015 14.6 4.1 2.4 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.9 OAJ08721.1 - 0.34 8.8 7.4 0.78 7.6 5.2 1.5 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 OAJ08721.1 - 1 7.2 14.1 2.1 6.1 7.5 2.6 3 0 0 3 3 3 0 Nop14-like family Pex14_N PF04695.8 OAJ08721.1 - 2.7 8.0 12.8 0.76 9.8 2.2 3.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WWbp PF10349.4 OAJ08721.1 - 4.4 8.2 10.0 34 5.3 7.0 2.5 1 0 0 1 1 1 0 WW-domain ligand protein DUF282 PF03380.9 OAJ08724.1 - 0.65 9.7 3.8 4.1 7.2 0.1 2.7 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF282 Chromate_transp PF02417.10 OAJ08727.1 - 1.9e-54 183.7 31.2 2.6e-29 102.0 7.1 2.9 3 1 0 3 3 3 2 Chromate transporter Flavin_Reduct PF01613.13 OAJ08730.1 - 4.3e-31 107.8 0.4 6.4e-31 107.2 0.3 1.3 1 0 0 1 1 1 1 Flavin reductase like domain ADK PF00406.17 OAJ08731.1 - 8.6e-43 145.8 0.0 1.1e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 OAJ08731.1 - 3.9e-11 42.4 0.0 8.3e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid Zeta_toxin PF06414.7 OAJ08731.1 - 0.001 18.2 0.0 0.0021 17.1 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 OAJ08731.1 - 0.0038 18.0 0.0 0.0059 17.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ08731.1 - 0.0059 16.4 0.0 0.016 15.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ08731.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain SGT1 PF07093.6 OAJ08732.1 - 5.1e-41 140.7 41.4 2.8e-36 125.1 0.4 2.6 1 1 2 3 3 3 2 SGT1 protein Asp PF00026.18 OAJ08736.1 - 1.3e-13 50.8 0.0 1.7e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Ribonuclease_3 PF00636.21 OAJ08737.1 - 1.6e-33 115.5 0.0 4.3e-18 65.8 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 OAJ08737.1 - 9.4e-18 64.4 0.9 3e-10 40.1 0.1 3.5 4 0 0 4 4 4 2 Ribonuclease-III-like DUF4351 PF14261.1 OAJ08737.1 - 0.096 12.5 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) DUF390 PF04094.9 OAJ08738.1 - 0.035 12.1 3.0 0.043 11.8 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) rve PF00665.21 OAJ08739.1 - 1.2e-13 51.2 0.0 3e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 OAJ08739.1 - 8.8e-05 21.8 0.3 0.00023 20.4 0.3 1.7 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 OAJ08740.1 - 0.047 13.0 0.0 0.12 11.6 0.0 1.9 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF605 PF04652.11 OAJ08741.1 - 0.00025 20.5 10.0 0.00027 20.4 6.9 1.1 1 0 0 1 1 1 1 Vta1 like DUF936 PF06075.7 OAJ08741.1 - 0.017 14.0 22.4 0.022 13.7 15.5 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SprA-related PF12118.3 OAJ08741.1 - 0.18 11.0 19.8 0.25 10.6 13.7 1.1 1 0 0 1 1 1 0 SprA-related family DUF2413 PF10310.4 OAJ08741.1 - 0.34 9.6 17.9 0.46 9.2 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF2201_N PF13203.1 OAJ08741.1 - 0.6 9.2 19.3 0.54 9.3 12.0 1.7 1 1 1 2 2 2 0 Putative metallopeptidase domain Peptidase_S64 PF08192.6 OAJ08741.1 - 0.64 8.2 17.6 0.85 7.8 12.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF4554 PF15091.1 OAJ08741.1 - 2.2 6.9 11.3 3.2 6.4 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) DUF4551 PF15087.1 OAJ08741.1 - 3 6.1 19.5 4.2 5.6 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hid1 PF12722.2 OAJ08741.1 - 3.5 5.2 17.2 4.2 4.9 11.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 OAJ08741.1 - 3.5 5.9 14.8 4.4 5.6 10.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOBP PF15279.1 OAJ08741.1 - 5.3 7.3 12.2 8.6 6.6 8.4 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein TMEM247 PF15444.1 OAJ08741.1 - 8.3 6.1 7.8 14 5.4 5.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 MIP-T3 PF10243.4 OAJ08741.1 - 9.7 4.5 26.4 14 4.0 18.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Rifin_STEVOR PF02009.11 OAJ08744.1 - 0.012 15.2 0.2 0.014 15.0 0.2 1.1 1 0 0 1 1 1 0 Rifin/stevor family MCPVI PF02993.9 OAJ08744.1 - 0.031 14.4 8.9 0.04 14.0 6.1 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Raftlin PF15250.1 OAJ08744.1 - 0.032 12.7 2.6 0.041 12.4 1.8 1.1 1 0 0 1 1 1 0 Raftlin Trypan_PARP PF05887.6 OAJ08744.1 - 0.036 13.8 0.2 0.052 13.3 0.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) BRF1 PF07741.8 OAJ08744.1 - 0.058 13.6 6.2 0.12 12.6 3.4 1.9 2 0 0 2 2 2 0 Brf1-like TBP-binding domain NARP1 PF12569.3 OAJ08744.1 - 0.17 10.6 5.0 0.21 10.2 3.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PAT1 PF09770.4 OAJ08744.1 - 0.53 8.4 17.0 0.6 8.2 11.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ERF PF04404.7 OAJ08744.1 - 0.64 9.5 10.0 1 8.8 6.9 1.2 1 0 0 1 1 1 0 ERF superfamily DUF4557 PF15101.1 OAJ08744.1 - 1 9.1 7.5 1.5 8.5 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Het-C PF07217.6 OAJ08744.1 - 3.5 5.6 5.3 4.2 5.4 0.0 2.0 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C G0-G1_switch_2 PF15103.1 OAJ08744.1 - 5.8 7.1 6.8 12 6.1 4.7 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF4175 PF13779.1 OAJ08744.1 - 7.3 4.1 17.0 9.4 3.7 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Peptidase_S49_N PF08496.5 OAJ08744.1 - 9.4 6.0 7.0 14 5.4 4.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Flag1_repress PF03614.8 OAJ08748.1 - 0.055 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Repressor of phase-1 flagellin MFS_1 PF07690.11 OAJ08751.1 - 1.6e-15 56.7 5.7 1.3e-06 27.3 1.9 3.3 2 1 0 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAJ08751.1 - 1.1e-11 43.8 0.0 7.9e-11 40.9 0.0 2.0 2 1 0 2 2 2 1 MFS/sugar transport protein PBP1_TM PF14812.1 OAJ08751.1 - 0.15 12.3 12.5 0.046 14.0 3.1 3.0 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF788 PF05620.6 OAJ08751.1 - 0.26 11.1 0.0 0.68 9.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Sigma70_ner PF04546.8 OAJ08751.1 - 0.66 9.5 6.5 0.56 9.7 2.3 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Dicty_REP PF05086.7 OAJ08751.1 - 0.82 7.3 1.7 1.3 6.6 1.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4611 PF15387.1 OAJ08751.1 - 1.1 9.4 10.0 2.5 8.3 4.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 OAJ08751.1 - 4.7 6.7 10.4 1.9 8.0 3.6 2.2 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 OAJ08751.1 - 7.5 6.8 16.3 1.9 8.7 6.8 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain ThiF PF00899.16 OAJ08752.1 - 1.7e-32 112.0 0.0 2.7e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 ThiF family Glyco_hydro_17 PF00332.13 OAJ08752.1 - 0.15 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 TrkA_N PF02254.13 OAJ08752.1 - 0.19 11.7 0.3 0.51 10.3 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Zip PF02535.17 OAJ08752.1 - 3.2 6.6 13.9 0.22 10.4 5.9 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter DDE_Tnp_4 PF13359.1 OAJ08757.1 - 7.1e-09 35.4 0.1 1.3e-08 34.5 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ08757.1 - 1.4e-05 24.6 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein IRK PF01007.15 OAJ08757.1 - 0.015 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Inward rectifier potassium channel Myb_DNA-bind_3 PF12776.2 OAJ08758.1 - 1.6e-05 25.4 0.2 3.2e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ08758.1 - 0.11 12.6 2.6 0.21 11.7 1.8 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DPPIV_N PF00930.16 OAJ08760.1 - 1.2e-71 241.2 0.0 3.6e-70 236.2 0.0 2.3 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 OAJ08760.1 - 2.1e-41 141.5 0.5 3.4e-41 140.8 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAJ08760.1 - 1.5e-05 24.7 0.3 4.8e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 OAJ08760.1 - 0.00014 21.4 0.6 0.00047 19.6 0.3 1.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 OAJ08760.1 - 0.031 12.7 0.0 0.084 11.3 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Pal1 PF08316.6 OAJ08769.1 - 6.8e-17 62.2 1.6 1.5e-16 61.1 1.0 1.7 1 1 0 1 1 1 1 Pal1 cell morphology protein PPP4R2 PF09184.6 OAJ08770.1 - 4.1e-14 52.8 0.0 4.1e-14 52.8 0.0 3.0 3 0 0 3 3 3 1 PPP4R2 UBN2 PF14223.1 OAJ08775.1 - 1.2e-06 28.2 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ08775.1 - 0.0018 18.1 1.1 0.0033 17.2 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ08775.1 - 0.035 13.6 2.6 0.061 12.8 1.8 1.4 1 0 0 1 1 1 0 Zinc knuckle UBN2_2 PF14227.1 OAJ08775.1 - 0.059 12.9 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Copper-fist PF00649.13 OAJ08775.1 - 0.71 9.1 2.7 0.51 9.5 0.2 2.0 3 0 0 3 3 3 0 Copper fist DNA binding domain RVT_2 PF07727.9 OAJ08776.1 - 2e-84 282.3 0.0 2.8e-84 281.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08776.1 - 4.6e-23 81.6 0.0 7.9e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ08776.1 - 1.7e-06 27.5 0.0 4.3e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ08776.1 - 0.00029 20.3 0.0 0.00068 19.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF45 PF01863.12 OAJ08780.1 - 4.2e-58 196.5 0.6 4.2e-58 196.5 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function DUF45 HSDR_N PF04313.9 OAJ08780.1 - 3.2e-35 121.6 0.0 1.5e-34 119.4 0.0 2.3 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) ResIII PF04851.10 OAJ08780.1 - 2.2e-18 66.7 0.0 5.9e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HATPase_c_4 PF13749.1 OAJ08780.1 - 6.9e-13 48.1 0.0 2.7e-12 46.2 0.0 2.1 1 0 0 1 1 1 1 ATP-dependent DNA helicase recG C-terminal WLM PF08325.5 OAJ08780.1 - 1.8e-06 27.9 0.1 5.7e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 WLM domain SprT-like PF10263.4 OAJ08780.1 - 0.00018 21.1 0.4 0.00044 19.9 0.2 1.6 1 0 0 1 1 1 1 SprT-like family SNF2_N PF00176.18 OAJ08780.1 - 0.014 14.2 0.0 0.058 12.1 0.0 2.1 1 1 0 1 1 1 0 SNF2 family N-terminal domain RimK PF08443.6 OAJ08780.1 - 0.056 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 RimK-like ATP-grasp domain DUF87 PF01935.12 OAJ08780.1 - 0.27 11.0 1.7 1.4 8.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 FHA PF00498.21 OAJ08787.1 - 0.042 13.9 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 FHA domain Daxx PF03344.10 OAJ08788.1 - 0.094 11.1 17.1 0.15 10.5 11.9 1.3 1 0 0 1 1 1 0 Daxx Family Pneumo_matrix PF03393.11 OAJ08788.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Pneumovirus matrix protein TEX15 PF15326.1 OAJ08788.1 - 0.15 11.6 1.1 0.27 10.8 0.8 1.4 1 0 0 1 1 1 0 Testis expressed sequence 15 Hid1 PF12722.2 OAJ08788.1 - 6.1 4.3 7.8 6.2 4.3 5.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CS PF04969.11 OAJ08792.1 - 3e-06 27.6 0.0 5.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 CS domain Serglycin PF04360.7 OAJ08792.1 - 0.0063 16.2 2.7 0.0063 16.2 1.8 3.3 3 0 0 3 3 3 1 Serglycin WD40 PF00400.27 OAJ08793.1 - 2.5e-63 207.8 16.4 1.4e-08 34.3 0.2 11.3 11 0 0 11 11 11 10 WD domain, G-beta repeat Nbas_N PF15492.1 OAJ08793.1 - 0.00023 20.3 1.2 0.23 10.5 0.0 3.9 4 0 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 OAJ08793.1 - 0.0012 17.6 0.2 1.6 7.4 0.0 4.2 4 1 0 5 5 5 1 Nup133 N terminal like Pox_Ag35 PF03286.9 OAJ08793.1 - 0.019 14.4 4.2 0.036 13.6 2.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2457 PF10446.4 OAJ08793.1 - 0.023 13.4 7.3 0.041 12.6 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.6 OAJ08793.1 - 0.035 11.9 3.2 0.061 11.1 2.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FLO_LFY PF01698.11 OAJ08793.1 - 0.23 10.2 4.2 0.44 9.3 2.9 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein CDC45 PF02724.9 OAJ08793.1 - 0.47 8.4 6.3 0.81 7.6 4.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 OAJ08793.1 - 0.77 9.7 6.7 1.6 8.7 4.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RXT2_N PF08595.6 OAJ08793.1 - 2 8.1 5.9 3.9 7.2 4.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal PTS_2-RNA PF01885.11 OAJ08797.1 - 7.5e-43 146.0 0.0 7.7e-42 142.7 0.0 2.4 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family FXR1P_C PF12235.3 OAJ08797.1 - 0.018 15.1 6.6 0.018 15.1 4.6 2.9 3 1 0 3 3 3 0 Fragile X-related 1 protein C terminal GLTP PF08718.6 OAJ08798.1 - 1.2e-43 148.7 0.0 1.7e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Ribosomal_L24e PF01246.15 OAJ08799.1 - 6e-32 109.3 0.7 6e-32 109.3 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e CLTH PF10607.4 OAJ08800.1 - 5.6e-29 100.6 0.0 7e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 OAJ08800.1 - 6.2e-06 25.7 0.7 1.1e-05 24.9 0.1 1.8 2 0 0 2 2 2 1 LisH Ribosomal_60s PF00428.14 OAJ08800.1 - 7.3e-06 26.2 7.1 1.7e-05 25.0 4.9 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein Nucleoplasmin PF03066.10 OAJ08800.1 - 0.0052 16.3 0.6 0.0076 15.7 0.4 1.2 1 0 0 1 1 1 1 Nucleoplasmin Myc_N PF01056.13 OAJ08800.1 - 0.048 12.8 1.6 0.075 12.1 1.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region BSP_II PF05432.6 OAJ08800.1 - 0.075 12.2 5.8 0.11 11.7 4.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Retinal PF15449.1 OAJ08800.1 - 0.096 10.3 0.4 0.12 10.0 0.2 1.1 1 0 0 1 1 1 0 Retinal protein PBP1_TM PF14812.1 OAJ08800.1 - 0.76 10.1 4.7 1.2 9.5 3.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LAT PF15234.1 OAJ08800.1 - 3.1 7.2 6.9 1.3 8.4 2.7 1.7 2 0 0 2 2 2 0 Linker for activation of T-cells TMEM220 PF15071.1 OAJ08803.1 - 0.078 13.4 0.1 0.34 11.3 0.0 2.0 2 0 0 2 2 2 0 Transmembrane family 220, helix DUF2345 PF10106.4 OAJ08806.1 - 4.4e-05 23.1 0.0 0.00011 21.8 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) IRF-2BP1_2 PF11261.3 OAJ08807.1 - 0.069 12.6 0.0 0.61 9.5 0.0 2.2 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger DUF2235 PF09994.4 OAJ08808.1 - 9.5e-45 153.0 0.0 2.2e-29 102.6 0.0 3.3 2 1 0 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF4123 PF13503.1 OAJ08809.1 - 9.6e-20 70.7 2.1 9.6e-20 70.7 1.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4123) RNase_H PF00075.19 OAJ08812.1 - 1.8e-17 63.9 0.0 2.8e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAJ08812.1 - 0.49 10.2 2.3 0.56 10.0 0.2 2.2 2 1 0 2 2 2 0 Reverse transcriptase-like TFIIA PF03153.8 OAJ08813.1 - 0.0011 18.9 2.1 0.0016 18.4 1.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RRN3 PF05327.6 OAJ08819.1 - 9.6e-134 446.5 0.0 4.4e-131 437.7 0.0 2.9 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 OAJ08819.1 - 0.11 10.9 13.6 0.25 9.8 9.4 1.5 1 0 0 1 1 1 0 Daxx Family Ribosomal_60s PF00428.14 OAJ08820.1 - 2.4 8.6 6.3 0.48 10.8 1.3 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein RVT_1 PF00078.22 OAJ08824.1 - 2.9e-18 66.0 0.0 5.1e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ApoO PF09769.4 OAJ08829.1 - 4.3e-32 111.0 0.7 7.6e-32 110.2 0.2 1.6 2 0 0 2 2 2 1 Apolipoprotein O DUF883 PF05957.8 OAJ08829.1 - 0.012 16.0 0.0 2.1 8.7 0.0 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 OAJ08829.1 - 0.068 12.6 0.5 5.1 6.5 0.2 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain HMGL-like PF00682.14 OAJ08830.1 - 1.1e-40 139.8 1.1 1.9e-39 135.7 0.8 2.6 1 1 0 1 1 1 1 HMGL-like ApoO PF09769.4 OAJ08831.1 - 0.0016 18.1 0.2 0.0018 17.9 0.1 1.2 1 0 0 1 1 1 1 Apolipoprotein O WXG100 PF06013.7 OAJ08831.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Methyltransf_15 PF09445.5 OAJ08844.1 - 1.3e-33 115.8 0.0 2.7e-27 95.3 0.0 2.4 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 OAJ08844.1 - 6.5e-10 39.0 0.0 1.5e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ08844.1 - 2.7e-07 31.1 0.0 6.9e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 OAJ08844.1 - 4.1e-07 29.7 0.0 6.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 OAJ08844.1 - 2.6e-05 23.8 0.0 5.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 OAJ08844.1 - 0.00011 21.7 0.0 0.00011 21.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 OAJ08844.1 - 0.00026 20.0 0.0 0.00043 19.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 OAJ08844.1 - 0.00067 19.9 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 OAJ08844.1 - 0.0043 16.2 1.1 0.012 14.8 0.7 1.6 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.6 OAJ08844.1 - 0.033 12.8 0.0 0.033 12.8 0.0 1.5 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase Cons_hypoth95 PF03602.10 OAJ08844.1 - 0.072 12.4 0.1 0.072 12.4 0.1 2.8 3 0 0 3 3 3 0 Conserved hypothetical protein 95 SAPS PF04499.10 OAJ08844.1 - 0.12 10.9 5.4 0.1 11.2 2.4 1.7 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein TRM PF02005.11 OAJ08844.1 - 0.16 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase SelP_N PF04592.9 OAJ08844.1 - 1.5 8.1 11.3 2.8 7.2 7.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CDK5_activator PF03261.10 OAJ08844.1 - 3.5 6.8 12.1 6.8 5.9 8.4 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein ABC_ATPase PF09818.4 OAJ08847.1 - 1.1e-123 413.1 0.0 1.6e-123 412.6 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_28 PF13521.1 OAJ08847.1 - 0.03 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.3 OAJ08847.1 - 0.039 13.0 0.6 0.92 8.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) ABC_tran PF00005.22 OAJ08847.1 - 0.14 12.4 1.8 0.75 10.0 1.3 2.1 1 1 0 1 1 1 0 ABC transporter Myb_DNA-bind_6 PF13921.1 OAJ08848.1 - 3.1e-12 46.4 0.0 0.00011 22.2 0.0 4.5 4 1 1 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 OAJ08848.1 - 3.3e-10 39.8 0.7 0.00064 19.7 0.0 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain Abhydrolase_5 PF12695.2 OAJ08858.1 - 6.6e-07 29.1 0.1 1.4e-06 28.1 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ08858.1 - 7.7e-06 25.9 0.1 0.00046 20.1 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ08858.1 - 0.057 12.9 0.0 0.23 10.9 0.0 1.8 1 1 0 2 2 2 0 alpha/beta hydrolase fold DDE_3 PF13358.1 OAJ08859.1 - 1.4e-14 54.0 0.0 2.7e-14 53.1 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 OAJ08859.1 - 6.5e-05 23.0 0.0 9.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.13 OAJ08864.1 - 1.1e-12 47.8 0.5 8.1e-11 41.8 0.2 2.3 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 OAJ08864.1 - 4e-07 30.1 1.2 1e-06 28.8 0.7 1.8 1 1 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 OAJ08864.1 - 0.00011 22.9 6.7 0.00018 22.2 1.0 3.1 3 1 1 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.1 OAJ08864.1 - 0.0078 15.7 0.0 0.027 14.0 0.0 2.0 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 OAJ08864.1 - 0.0085 15.2 0.0 0.025 13.7 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.1 OAJ08864.1 - 0.0086 15.7 0.0 0.0086 15.7 0.0 2.3 3 0 0 3 3 3 1 Homeodomain-like domain DDE_3 PF13358.1 OAJ08864.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF2789 PF10982.3 OAJ08864.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) HTH_28 PF13518.1 OAJ08864.1 - 1.7 8.7 6.4 0.86 9.6 0.1 3.1 3 1 0 3 3 3 0 Helix-turn-helix domain ABC2_membrane PF01061.19 OAJ08865.1 - 2.1e-26 92.3 11.7 2.8e-26 91.9 8.1 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 OAJ08865.1 - 1.7e-17 64.0 0.0 2e-15 57.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 OAJ08865.1 - 2e-13 50.2 0.1 4.3e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal HLH PF00010.21 OAJ08868.1 - 9.4e-10 38.0 0.2 1.8e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GTP_EFTU PF00009.22 OAJ08869.1 - 3.6e-33 114.5 0.2 2.8e-25 88.8 0.6 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ08869.1 - 6.4e-06 26.1 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 OAJ08869.1 - 0.0028 16.9 0.0 0.036 13.3 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit IF2_N PF04760.10 OAJ08869.1 - 0.007 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Miro PF08477.8 OAJ08869.1 - 0.029 14.8 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 OAJ08869.1 - 0.094 11.9 0.0 4.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B MobB PF03205.9 OAJ08869.1 - 0.13 11.9 0.1 0.29 10.8 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Abhydrolase_6 PF12697.2 OAJ08874.1 - 9.6e-10 38.7 1.2 1.5e-09 38.0 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 OAJ08874.1 - 2.1e-06 26.8 0.0 4.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.2 OAJ08874.1 - 2.9e-06 27.1 0.0 5.2e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ08874.1 - 0.079 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF915 PF06028.6 OAJ08874.1 - 0.15 11.1 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) MARVEL PF01284.18 OAJ08876.1 - 3.4e-12 46.4 9.5 4.5e-12 46.0 6.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4064 PF13273.1 OAJ08876.1 - 0.23 11.5 8.6 0.49 10.5 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Snf7 PF03357.16 OAJ08877.1 - 2.6e-30 105.0 18.5 2.6e-30 105.0 12.8 1.3 1 1 0 1 1 1 1 Snf7 DUF2428 PF10350.4 OAJ08877.1 - 0.042 12.8 0.5 0.069 12.1 0.3 1.3 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) LIM PF00412.17 OAJ08878.1 - 9.1e-33 112.1 25.3 2.1e-13 50.1 2.1 5.3 5 0 0 5 5 5 5 LIM domain BCDHK_Adom3 PF10436.4 OAJ08882.1 - 1.6e-09 37.4 0.0 2.4e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 OAJ08882.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cutinase PF01083.17 OAJ08883.1 - 0.00096 18.9 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Cutinase BCDHK_Adom3 PF10436.4 OAJ08884.1 - 1.2e-12 47.5 0.0 1.5e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase SelP_N PF04592.9 OAJ08887.1 - 0.29 10.4 4.2 0.3 10.4 2.9 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Vfa1 PF08432.5 OAJ08887.1 - 0.31 11.0 18.5 0.34 10.9 12.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1897 PF09005.5 OAJ08887.1 - 0.59 9.6 3.7 2.5 7.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1897) FYDLN_acid PF09538.5 OAJ08887.1 - 4 8.0 36.6 4.6 7.8 25.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Rhabdo_ncap PF00945.13 OAJ08887.1 - 4.3 5.8 10.4 5.2 5.5 7.2 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF3449 PF11931.3 OAJ08887.1 - 5.7 6.4 9.2 6.5 6.2 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) CDC45 PF02724.9 OAJ08887.1 - 6.9 4.5 26.8 7.5 4.4 18.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Dala_Dala_lig_C PF07478.8 OAJ08890.1 - 0.079 12.3 0.2 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF4337 PF14235.1 OAJ08895.1 - 0.07 12.9 8.4 0.015 15.0 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) MTBP_C PF14920.1 OAJ08895.1 - 7.8 5.8 11.1 34 3.7 7.7 2.0 1 1 0 1 1 1 0 MDM2-binding Cytochrom_B_N PF00033.14 OAJ08896.1 - 0.0034 16.7 4.4 0.006 15.9 3.0 1.5 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB 7tm_7 PF08395.7 OAJ08896.1 - 0.12 11.3 0.8 0.17 10.8 0.6 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Ni_hydr_CYTB PF01292.15 OAJ08896.1 - 0.33 10.3 6.2 0.29 10.5 3.3 1.6 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF2628 PF10947.3 OAJ08896.1 - 6.3 6.6 7.0 4.5 7.1 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2628) Phage_integrase PF00589.17 OAJ08900.1 - 2.9e-06 27.0 0.0 8.8e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.1 OAJ08900.1 - 0.14 12.5 0.2 0.9 9.9 0.0 2.4 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain zf-CCHC_4 PF14392.1 OAJ08901.1 - 0.8 9.4 3.3 5.7 6.7 0.2 2.3 2 0 0 2 2 2 0 Zinc knuckle Histone PF00125.19 OAJ08906.1 - 2.4e-28 98.0 0.8 3.7e-28 97.4 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ08906.1 - 3.3e-05 23.9 0.0 5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 OAJ08906.1 - 0.049 12.8 0.8 0.07 12.3 0.6 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T WD40 PF00400.27 OAJ08907.1 - 1.3e-37 126.3 3.3 7.7e-09 35.1 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 OAJ08907.1 - 3.1e-06 27.0 0.1 1.7e-05 24.6 0.1 2.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PfkB PF00294.19 OAJ08911.1 - 3.1e-09 36.4 0.6 5.4e-07 29.0 0.0 2.6 3 0 0 3 3 3 2 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 OAJ08911.1 - 4.5e-09 35.8 0.0 9.9e-09 34.7 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DUF1793 PF08760.6 OAJ08912.1 - 1e-66 224.0 0.5 2e-66 223.0 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) RVT_1 PF00078.22 OAJ08916.1 - 3.2e-15 56.0 0.0 5.9e-14 51.9 0.0 2.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.17 OAJ08919.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 Phage integrase family DDE_1 PF03184.14 OAJ08927.1 - 3.5e-25 88.4 0.0 8.8e-14 51.1 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease AMP-binding PF00501.23 OAJ08931.1 - 1.1e-71 241.5 0.0 2e-48 164.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ08931.1 - 2e-10 41.4 0.3 2e-08 35.0 0.0 3.4 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain UDPGP PF01704.13 OAJ08932.1 - 2.4e-30 105.4 0.0 3e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase rve PF00665.21 OAJ08939.1 - 2.7e-13 50.0 0.0 5.3e-12 45.8 0.0 2.6 2 1 1 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ08939.1 - 2.6e-07 30.1 0.0 2.1e-06 27.2 0.0 2.4 2 1 0 2 2 2 1 GAG-pre-integrase domain UBN2 PF14223.1 OAJ08939.1 - 0.00031 20.5 0.0 0.00062 19.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Transcript_VP30 PF11507.3 OAJ08939.1 - 0.014 15.1 0.4 0.038 13.8 0.0 1.8 2 0 0 2 2 2 0 Ebola virus-specific transcription factor VP30 RVT_2 PF07727.9 OAJ08940.1 - 2.1e-82 275.7 0.0 3e-82 275.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAJ08940.1 - 0.036 13.4 0.0 0.088 12.1 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PTCB-BRCT PF12738.2 OAJ08946.1 - 1.8e-30 104.5 0.5 8.8e-19 67.1 0.1 5.3 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.21 OAJ08946.1 - 8e-26 90.0 0.0 3.9e-12 46.1 0.0 7.1 7 1 0 7 7 7 5 BRCA1 C Terminus (BRCT) domain UPF0183 PF03676.9 OAJ08947.1 - 2.3e-12 46.2 0.0 6.7e-06 24.9 0.1 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0183) TSA PF03249.8 OAJ08947.1 - 6.9 5.0 7.4 9.7 4.5 5.1 1.1 1 0 0 1 1 1 0 Type specific antigen ABC2_membrane PF01061.19 OAJ08953.1 - 3.2e-36 124.4 19.1 3.2e-36 124.4 13.2 2.1 3 0 0 3 3 2 1 ABC-2 type transporter ABC_tran PF00005.22 OAJ08953.1 - 8e-25 87.7 0.0 1.3e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 OAJ08953.1 - 2.3e-09 37.6 0.0 1.9e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 OAJ08953.1 - 2.1e-05 23.7 25.7 5.2e-05 22.4 17.8 1.7 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 OAJ08953.1 - 0.0008 18.8 0.1 0.022 14.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ08953.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 OAJ08953.1 - 0.021 14.3 0.1 0.073 12.6 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 OAJ08953.1 - 0.025 15.3 0.0 0.047 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 OAJ08953.1 - 0.025 13.6 0.0 6 5.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 OAJ08953.1 - 0.041 14.1 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 OAJ08953.1 - 0.058 12.5 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 OAJ08953.1 - 0.083 12.8 0.0 0.52 10.2 0.0 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.10 OAJ08953.1 - 0.088 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 OAJ08953.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 OAJ08953.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 OAJ08953.1 - 0.23 11.4 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 OAJ08953.1 - 0.23 11.7 0.1 0.41 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 OAJ08953.1 - 0.23 11.1 0.0 0.44 10.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IlvN PF07991.7 OAJ08959.1 - 9.4e-47 158.4 0.0 1.6e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 OAJ08959.1 - 8e-37 126.3 0.0 1.2e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 OAJ08959.1 - 0.051 13.4 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 OAJ08959.1 - 0.091 13.2 0.4 0.23 11.9 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_4 PF02390.12 OAJ08960.1 - 5.5e-50 169.1 0.0 7.2e-38 129.6 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 OAJ08960.1 - 0.008 16.7 0.2 0.12 12.9 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ08960.1 - 0.021 15.2 0.0 0.077 13.4 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ08960.1 - 0.044 14.1 0.1 0.16 12.3 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Glycos_transf_2 PF00535.21 OAJ08960.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 ETF PF01012.16 OAJ08964.1 - 1.6e-35 122.2 3.9 2.2e-35 121.8 2.7 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF1751 PF08551.5 OAJ08965.1 - 2.8e-26 91.7 7.1 5.4e-26 90.8 4.9 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 OAJ08965.1 - 0.0013 18.7 12.6 0.003 17.5 8.8 1.6 1 0 0 1 1 1 1 Rhomboid family RVT_1 PF00078.22 OAJ08969.1 - 6.9e-16 58.2 0.0 1.4e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08969.1 - 2e-11 44.0 0.2 4.4e-10 39.7 0.0 3.0 2 1 1 3 3 3 1 Integrase core domain rve_3 PF13683.1 OAJ08969.1 - 0.02 14.4 0.0 0.064 12.7 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.22 OAJ08973.1 - 4.5e-16 58.8 0.0 8.4e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ08973.1 - 1.1e-11 44.9 0.0 2.4e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ08981.1 - 7.7e-18 64.6 0.0 1.3e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ08981.1 - 0.00076 19.9 0.0 0.0018 18.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ08981.1 - 0.0097 15.8 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ08981.1 - 0.013 15.3 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease rve PF00665.21 OAJ08982.1 - 0.029 14.4 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain COesterase PF00135.23 OAJ08988.1 - 2e-69 234.7 0.0 2.4e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ08988.1 - 2.4e-08 33.7 2.1 3.2e-05 23.5 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold OTU PF02338.14 OAJ08989.1 - 1.2e-10 42.0 0.0 2.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease DUF2360 PF10152.4 OAJ08989.1 - 0.091 13.0 2.0 0.16 12.2 1.4 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Mu-like_Com PF10122.4 OAJ08989.1 - 0.2 10.7 0.3 0.46 9.5 0.2 1.6 1 0 0 1 1 1 0 Mu-like prophage protein Com DUF605 PF04652.11 OAJ08989.1 - 0.44 9.9 8.5 0.55 9.5 5.9 1.1 1 0 0 1 1 1 0 Vta1 like DUF4106 PF13388.1 OAJ08989.1 - 1 8.2 4.6 1.6 7.5 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) TP2 PF01254.13 OAJ08991.1 - 0.54 10.5 5.9 1.3 9.3 4.1 1.6 1 0 0 1 1 1 0 Nuclear transition protein 2 Med3 PF11593.3 OAJ08991.1 - 3.6 6.7 5.4 5.6 6.0 3.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal rve PF00665.21 OAJ08992.1 - 3.4e-15 56.2 0.0 6.4e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ08992.1 - 9.9e-15 54.4 0.0 1.8e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MULE PF10551.4 OAJ08996.1 - 2.9e-15 56.1 0.0 5.4e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ08996.1 - 0.00077 18.1 0.0 0.00098 17.7 0.0 1.1 1 0 0 1 1 1 1 Transposase, Mutator family DUF4131 PF13567.1 OAJ08997.1 - 0.95 8.8 4.6 0.34 10.3 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3818 PF12825.2 OAJ08999.1 - 5.4e-117 390.2 0.0 8e-117 389.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 OAJ08999.1 - 2.8e-39 133.8 0.2 5.7e-39 132.8 0.1 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.19 OAJ08999.1 - 5e-09 35.9 0.0 2.1e-08 33.9 0.0 2.0 1 0 0 1 1 1 1 PX domain NOA36 PF06524.7 OAJ08999.1 - 0.62 9.2 3.2 1.5 8.0 2.3 1.6 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 OAJ08999.1 - 3.2 7.2 11.1 1.7 8.1 4.9 2.7 3 0 0 3 3 3 0 Nucleoplasmin Methyltransf_26 PF13659.1 OAJ09000.1 - 4.6e-13 49.2 0.0 7.1e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ09000.1 - 2.7e-08 33.5 0.0 4.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ09000.1 - 5.6e-08 33.3 0.0 1.1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 OAJ09000.1 - 2.9e-06 26.5 0.0 3.9e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_25 PF13649.1 OAJ09000.1 - 6.3e-06 26.4 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ09000.1 - 0.00012 21.4 0.4 0.0072 15.7 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase small domain UPF0020 PF01170.13 OAJ09000.1 - 0.0012 18.4 0.2 0.046 13.2 0.0 2.1 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 OAJ09000.1 - 0.0097 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 OAJ09000.1 - 0.012 14.7 0.1 0.027 13.6 0.1 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_10 PF05971.7 OAJ09000.1 - 0.025 13.7 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF890) Methyltransf_15 PF09445.5 OAJ09000.1 - 0.035 13.6 0.0 0.073 12.6 0.0 1.6 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.1 OAJ09000.1 - 0.07 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ09000.1 - 0.1 13.0 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Nop10p PF04135.7 OAJ09001.1 - 1.6e-06 27.6 0.0 1.9e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DUF3446 PF11928.3 OAJ09004.1 - 0.025 14.7 1.1 0.037 14.2 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DUF3439 PF11921.3 OAJ09004.1 - 0.7 9.6 5.4 0.97 9.2 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) GTP_EFTU PF00009.22 OAJ09011.1 - 3.2e-56 189.7 0.0 4.9e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 OAJ09011.1 - 1.6e-35 121.1 0.1 4.2e-35 119.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 OAJ09011.1 - 5.1e-16 58.5 1.0 5.1e-16 58.5 0.7 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 OAJ09011.1 - 0.00095 18.7 0.4 0.0026 17.3 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 OAJ09011.1 - 0.002 18.0 0.5 0.0073 16.2 0.3 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 OAJ09011.1 - 0.083 12.4 0.2 4 7.0 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Glyco_trans_1_4 PF13692.1 OAJ09016.1 - 3.6e-18 66.0 0.1 2.8e-15 56.6 0.0 3.6 4 0 0 4 4 4 2 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 OAJ09016.1 - 4.7e-05 22.8 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 OAJ09016.1 - 9.4e-05 22.6 0.0 0.00028 21.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 RVT_2 PF07727.9 OAJ09017.1 - 4.1e-81 271.5 0.0 5.3e-81 271.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CTF_NFI PF00859.13 OAJ09022.1 - 0.00023 21.0 2.2 0.00037 20.3 1.5 1.3 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region 4HBT PF03061.17 OAJ09022.1 - 0.0018 18.3 0.8 0.012 15.6 0.0 2.4 3 0 0 3 3 3 1 Thioesterase superfamily SR-25 PF10500.4 OAJ09022.1 - 0.8 9.1 12.0 0.099 12.0 5.2 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF515 PF04415.7 OAJ09022.1 - 1 7.5 4.2 1.5 6.9 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Apolipoprotein PF01442.13 OAJ09023.1 - 0.19 11.2 4.1 0.14 11.6 1.9 1.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Zip PF02535.17 OAJ09024.1 - 0.28 10.1 4.2 0.42 9.5 2.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter UPF0560 PF10577.4 OAJ09024.1 - 3 5.9 11.1 4.9 5.2 7.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Suf PF05843.9 OAJ09024.1 - 6.9 6.3 5.6 14 5.3 3.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Serglycin PF04360.7 OAJ09024.1 - 9.6 5.9 18.9 7.1 6.3 2.4 2.8 2 0 0 2 2 2 0 Serglycin PepSY_TM_2 PF13703.1 OAJ09027.1 - 0.0065 16.6 1.2 0.0065 16.6 0.9 3.2 3 0 0 3 3 3 1 PepSY-associated TM helix Solute_trans_a PF03619.11 OAJ09028.1 - 0.071 12.4 0.9 0.1 11.8 0.6 1.2 1 0 0 1 1 1 0 Organic solute transporter Ostalpha RVT_1 PF00078.22 OAJ09032.1 - 1.1e-17 64.1 0.0 2.6e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09032.1 - 3.6e-14 52.9 0.0 9.4e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ09032.1 - 0.0018 18.7 0.1 0.0068 16.8 0.1 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ09032.1 - 0.003 17.4 0.0 0.0062 16.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DDE_3 PF13358.1 OAJ09038.1 - 2.3e-29 102.0 0.0 3.6e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAJ09038.1 - 9.3e-07 29.5 0.3 3.1e-06 27.8 0.2 2.0 1 1 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.1 OAJ09038.1 - 3.6e-05 23.1 0.3 0.013 15.0 0.0 3.0 3 0 0 3 3 3 1 Winged helix-turn helix DDE_1 PF03184.14 OAJ09038.1 - 0.00056 19.1 0.0 0.00093 18.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 OAJ09038.1 - 0.0012 18.9 0.0 0.0033 17.5 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain HTH_29 PF13551.1 OAJ09038.1 - 0.082 13.0 0.1 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Peptidase_M28 PF04389.12 OAJ09041.1 - 6.4e-27 94.4 0.0 1.5e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 OAJ09041.1 - 0.037 13.5 0.1 0.091 12.2 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 Cyclin_N PF00134.18 OAJ09042.1 - 1.4e-41 141.0 0.8 2.7e-41 140.0 0.2 1.8 2 1 1 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ09042.1 - 2.4e-28 98.4 0.0 7.3e-28 96.8 0.0 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain TP2 PF01254.13 OAJ09050.1 - 0.002 18.4 2.1 0.003 17.8 1.4 1.3 1 0 0 1 1 1 1 Nuclear transition protein 2 BNIP3 PF06553.7 OAJ09050.1 - 0.21 10.9 1.3 0.27 10.5 0.9 1.3 1 1 0 1 1 1 0 BNIP3 LRR_8 PF13855.1 OAJ09055.1 - 0.029 14.1 0.1 0.35 10.6 0.0 3.0 3 0 0 3 3 3 0 Leucine rich repeat DnaJ-X PF14308.1 OAJ09056.1 - 8.7e-46 155.7 1.5 2e-45 154.5 1.0 1.6 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 OAJ09056.1 - 1.2e-25 88.9 0.4 1.2e-25 88.9 0.3 2.5 3 0 0 3 3 3 1 DnaJ domain Ribonucleas_3_3 PF14622.1 OAJ09058.1 - 1.5e-07 31.3 0.0 0.026 14.4 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 OAJ09058.1 - 1.6e-05 25.3 0.0 4.7e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.20 OAJ09058.1 - 0.091 13.3 0.0 0.091 13.3 0.0 2.0 2 0 0 2 2 2 0 Double-stranded RNA binding motif WD40 PF00400.27 OAJ09059.1 - 7.4e-43 142.9 13.1 2.4e-12 46.1 0.3 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 OAJ09059.1 - 0.0017 17.4 0.4 0.016 14.2 0.0 2.6 4 0 0 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.3 OAJ09059.1 - 0.013 13.6 4.4 0.37 8.8 0.0 3.7 3 2 1 4 4 4 0 Nucleoporin Nup120/160 DUF605 PF04652.11 OAJ09059.1 - 1.2 8.4 12.6 1.6 8.0 8.8 1.1 1 0 0 1 1 1 0 Vta1 like Ribosomal_L35Ae PF01247.13 OAJ09060.1 - 2.8e-39 132.8 0.8 3.1e-39 132.6 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 OAJ09060.1 - 0.086 12.7 0.1 12 5.9 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain IPPT PF01715.12 OAJ09061.1 - 1.9e-10 40.2 0.0 2.4e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 OAJ09061.1 - 5.8e-05 23.9 0.0 6.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ09061.1 - 0.0031 17.2 0.0 0.0072 16.0 0.0 1.6 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 OAJ09061.1 - 0.0037 17.2 0.1 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ09061.1 - 0.0043 17.1 0.0 0.0053 16.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ09061.1 - 0.0061 16.8 0.0 0.0061 16.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 OAJ09061.1 - 0.0061 15.8 0.0 0.0098 15.1 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein IPT PF01745.11 OAJ09061.1 - 0.013 14.6 0.4 0.19 10.8 0.2 2.0 1 1 0 1 1 1 0 Isopentenyl transferase AAA_25 PF13481.1 OAJ09061.1 - 0.018 14.4 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 OAJ09061.1 - 0.026 14.4 0.1 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 OAJ09061.1 - 0.028 14.3 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 OAJ09061.1 - 0.08 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein MobB PF03205.9 OAJ09061.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 OAJ09061.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 RNA helicase VID27 PF08553.5 OAJ09065.1 - 4.8e-07 28.4 0.4 1.8e-06 26.5 0.2 1.7 1 1 0 1 1 1 1 VID27 cytoplasmic protein 2OG-FeII_Oxy_3 PF13640.1 OAJ09066.1 - 0.00023 21.6 0.1 0.00048 20.5 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ09066.1 - 0.00081 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 OAJ09069.1 - 6.3e-26 91.0 0.0 8.4e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ09069.1 - 8.4e-13 47.9 0.0 1.3e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ09069.1 - 0.076 12.7 0.1 0.31 10.7 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family DDE_1 PF03184.14 OAJ09070.1 - 5.3e-19 68.2 1.9 2.8e-17 62.5 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease Ribosomal_60s PF00428.14 OAJ09070.1 - 0.003 17.9 4.1 0.056 13.8 2.3 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein DDE_3 PF13358.1 OAJ09070.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF4336 PF14234.1 OAJ09076.1 - 0.0021 17.2 0.0 0.26 10.4 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) ODV-E18 PF10717.4 OAJ09077.1 - 0.087 12.2 0.0 0.25 10.8 0.0 1.8 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Heme_oxygenase PF01126.15 OAJ09078.1 - 3.7e-08 33.1 0.0 3.5e-06 26.7 0.0 2.9 3 1 0 3 3 3 2 Heme oxygenase PWWP PF00855.12 OAJ09085.1 - 1.2e-14 54.3 0.1 1.2e-14 54.3 0.1 2.3 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.6 OAJ09085.1 - 5.7e-05 22.5 0.4 0.00013 21.3 0.0 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain YL1 PF05764.8 OAJ09085.1 - 0.0033 17.0 16.0 0.0033 17.0 11.1 1.8 2 0 0 2 2 2 1 YL1 nuclear protein Daxx PF03344.10 OAJ09085.1 - 0.98 7.8 20.1 1.5 7.2 13.9 1.3 1 0 0 1 1 1 0 Daxx Family Abhydrolase_3 PF07859.8 OAJ09086.1 - 1.5e-23 83.4 0.0 1.9e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ09086.1 - 8.1e-10 38.6 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 OAJ09086.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Cutinase DLH PF01738.13 OAJ09086.1 - 0.0028 16.9 0.1 2.3 7.4 0.0 2.4 2 1 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.16 OAJ09086.1 - 0.0082 15.3 0.0 0.03 13.5 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2974 PF11187.3 OAJ09086.1 - 0.19 11.0 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Ras PF00071.17 OAJ09087.1 - 2.3e-50 170.1 0.2 3.2e-50 169.6 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ09087.1 - 6.1e-15 55.7 0.0 1.1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ09087.1 - 5.4e-11 42.0 0.0 1.8e-10 40.3 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 OAJ09087.1 - 1.2e-05 25.2 0.0 2.6e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAJ09087.1 - 0.00033 20.1 0.0 0.00099 18.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 OAJ09087.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 OAJ09087.1 - 0.0056 16.5 0.5 0.018 14.8 0.3 2.1 1 1 0 1 1 1 1 Dynamin family DUF89 PF01937.14 OAJ09087.1 - 0.024 13.4 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF89 Pollen_Ole_e_I PF01190.12 OAJ09093.1 - 0.013 15.2 0.1 0.019 14.7 0.1 1.2 1 0 0 1 1 1 0 Pollen proteins Ole e I like PorB PF11565.3 OAJ09093.1 - 0.051 13.7 0.1 0.077 13.2 0.1 1.3 1 0 0 1 1 1 0 Alpha helical Porin B RVT_3 PF13456.1 OAJ09095.1 - 0.0019 17.9 0.1 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like DNA_pol_viral_C PF00336.13 OAJ09095.1 - 0.014 14.6 0.0 0.029 13.6 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain RVT_1 PF00078.22 OAJ09095.1 - 0.13 11.5 0.0 0.32 10.3 0.0 1.6 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.17 OAJ09096.1 - 0.00034 20.3 0.0 0.00071 19.2 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Exo_endo_phos PF03372.18 OAJ09102.1 - 4.2e-13 49.7 4.9 6.6e-13 49.1 3.4 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.11 OAJ09103.1 - 9.2e-27 93.6 34.7 2e-26 92.5 22.9 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ09103.1 - 5.8e-12 44.9 19.7 9.1e-11 40.9 6.2 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter Peptidase_S10 PF00450.17 OAJ09109.1 - 1.1e-84 285.0 0.0 2.9e-83 280.3 0.0 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase Myb_DNA-binding PF00249.26 OAJ09110.1 - 7.6e-17 61.0 0.9 1.3e-11 44.3 0.2 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ09110.1 - 2.5e-09 37.0 12.8 5.6e-09 35.9 0.2 3.8 3 1 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ09110.1 - 0.0014 18.7 11.5 0.0062 16.6 0.4 3.8 2 2 1 3 3 3 2 Myb/SANT-like DNA-binding domain DUF3782 PF12644.2 OAJ09110.1 - 0.17 11.6 1.5 0.37 10.6 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) DUF1793 PF08760.6 OAJ09115.1 - 2.2e-67 226.1 0.8 3.1e-67 225.7 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DEAD PF00270.24 OAJ09120.1 - 0.00065 19.2 0.0 0.00084 18.8 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Mto2_bdg PF12808.2 OAJ09125.1 - 0.003 17.6 0.3 0.018 15.1 0.0 2.0 2 0 0 2 2 2 1 Micro-tubular organiser Mto1 C-term Mto2-binding region TarH PF02203.10 OAJ09125.1 - 0.0037 17.1 1.0 0.0044 16.8 0.7 1.1 1 0 0 1 1 1 1 Tar ligand binding domain homologue DUF2130 PF09903.4 OAJ09125.1 - 0.014 14.1 0.2 0.016 13.9 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) ATG16 PF08614.6 OAJ09125.1 - 0.022 14.5 0.3 0.031 14.0 0.2 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 OAJ09125.1 - 0.035 13.9 0.1 0.047 13.5 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Alkyl_sulf_C PF14864.1 OAJ09125.1 - 0.037 14.0 0.3 0.051 13.5 0.2 1.2 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal ADIP PF11559.3 OAJ09125.1 - 0.079 12.8 0.6 0.1 12.5 0.4 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding RVT_1 PF00078.22 OAJ09130.1 - 1.1e-16 60.8 0.0 1.9e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09130.1 - 1.6e-13 50.8 0.0 3.3e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ09130.1 - 1.2e-06 28.9 0.1 6.2e-06 26.6 0.1 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ09130.1 - 0.0044 16.7 0.1 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ09130.1 - 0.37 10.7 0.0 0.89 9.5 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease MarB PF13999.1 OAJ09135.1 - 0.061 12.9 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 MarB protein PepSY_2 PF13670.1 OAJ09135.1 - 0.1 12.5 0.8 0.13 12.1 0.6 1.1 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain TraW_N PF12477.3 OAJ09135.1 - 3.7 7.5 6.3 5.3 7.1 4.4 1.2 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal Phage_integrase PF00589.17 OAJ09139.1 - 0.012 15.2 0.0 0.048 13.3 0.0 2.0 1 1 0 1 1 1 0 Phage integrase family Rad60-SLD PF11976.3 OAJ09143.1 - 0.08 12.6 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 OAJ09143.1 - 0.086 12.2 0.0 0.35 10.3 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin family Ldh_1_N PF00056.18 OAJ09147.1 - 6.7e-46 155.6 0.5 9.9e-46 155.0 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 OAJ09147.1 - 7.8e-42 142.9 0.0 1.1e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 OAJ09147.1 - 9.2e-06 24.5 0.0 1.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 OAJ09147.1 - 0.0021 17.1 0.2 0.036 13.1 0.2 2.3 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.11 OAJ09147.1 - 0.038 13.2 0.1 1.4 8.1 0.0 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Mito_carr PF00153.22 OAJ09148.1 - 3.2e-32 110.0 3.0 1.1e-17 63.5 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4232 PF14016.1 OAJ09152.1 - 0.15 11.7 3.6 0.18 11.4 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) Thi4 PF01946.12 OAJ09153.1 - 9.2e-12 44.5 0.0 1.1e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Thi4 family TPR_12 PF13424.1 OAJ09154.1 - 1.1e-06 28.4 0.9 0.00013 21.8 0.2 3.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ09154.1 - 0.0036 17.1 2.3 3.7 7.6 0.8 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat AstE_AspA PF04952.9 OAJ09154.1 - 0.0064 15.4 0.2 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family TPR_11 PF13414.1 OAJ09154.1 - 0.01 15.4 0.2 0.037 13.6 0.1 2.0 1 0 0 1 1 1 0 TPR repeat TPR_19 PF14559.1 OAJ09154.1 - 0.068 13.5 2.1 0.16 12.2 0.1 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ09154.1 - 0.11 12.5 1.2 12 6.1 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_45 PF02015.11 OAJ09157.1 - 1.3e-51 175.5 5.6 1.6e-51 175.2 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 SelP_N PF04592.9 OAJ09157.1 - 5.8 6.2 12.4 10 5.4 8.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFIIA PF03153.8 OAJ09158.1 - 0.022 14.6 8.6 0.025 14.4 5.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 OAJ09158.1 - 0.034 12.0 14.1 0.042 11.7 9.8 1.0 1 0 0 1 1 1 0 Nop14-like family ERM PF00769.14 OAJ09158.1 - 0.058 12.9 3.3 0.087 12.3 2.3 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Na_trans_assoc PF06512.8 OAJ09158.1 - 0.079 12.9 4.1 0.1 12.5 2.9 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated CDC45 PF02724.9 OAJ09158.1 - 0.23 9.4 7.3 0.3 9.0 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 OAJ09158.1 - 0.4 10.3 8.7 0.58 9.8 6.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.6 OAJ09158.1 - 0.64 9.5 8.6 0.89 9.0 6.0 1.3 1 0 0 1 1 1 0 PPP4R2 Tom22 PF04281.8 OAJ09158.1 - 0.9 9.0 5.2 1.5 8.3 3.6 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 SURF2 PF05477.6 OAJ09158.1 - 1 8.4 7.4 1.5 7.8 5.2 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) VID27 PF08553.5 OAJ09158.1 - 1.2 7.3 6.8 1.5 6.9 4.7 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein CobT PF06213.7 OAJ09158.1 - 1.8 7.6 14.3 2.3 7.2 9.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1510 PF07423.6 OAJ09158.1 - 1.9 7.7 8.1 3.1 7.1 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sigma70_ner PF04546.8 OAJ09158.1 - 3.1 7.3 12.2 4.5 6.8 8.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Ebola_NP PF05505.7 OAJ09158.1 - 3.7 5.4 7.5 4.6 5.1 5.2 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein TRAP_alpha PF03896.11 OAJ09158.1 - 6.3 5.6 10.4 9.2 5.1 7.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SOBP PF15279.1 OAJ09158.1 - 6.7 7.0 6.0 39 4.4 4.2 1.9 1 1 0 1 1 1 0 Sine oculis-binding protein E1-E2_ATPase PF00122.15 OAJ09162.1 - 1.5e-14 53.5 3.8 3e-14 52.6 0.0 2.7 2 1 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 OAJ09162.1 - 6.1e-14 52.6 0.2 2.5e-13 50.6 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAJ09162.1 - 1.1e-13 52.1 0.4 7.9e-12 46.0 0.3 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ09162.1 - 9.8e-12 44.6 0.0 2.2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAJ09162.1 - 0.002 17.7 0.1 0.0054 16.3 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RVT_1 PF00078.22 OAJ09170.1 - 8.6e-24 84.0 0.0 1.4e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 OAJ09175.1 - 3.4e-72 242.3 0.0 5.7e-72 241.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09175.1 - 6.6e-22 77.8 0.1 3e-20 72.5 0.0 3.0 3 0 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ09175.1 - 4.8e-07 29.3 0.0 1.1e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 OAJ09175.1 - 2.3e-06 27.2 1.9 2.3e-06 27.2 1.3 1.8 2 0 0 2 2 2 1 Zinc knuckle rve_3 PF13683.1 OAJ09175.1 - 0.001 18.5 0.0 0.0025 17.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain UBN2_2 PF14227.1 OAJ09175.1 - 0.027 14.0 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type PsbX PF06596.6 OAJ09177.1 - 0.047 13.3 1.5 0.094 12.4 1.1 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) SAP18 PF06487.7 OAJ09180.1 - 6.6e-08 32.3 0.0 1.5e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) UPF0254 PF06787.6 OAJ09180.1 - 0.0052 16.3 0.3 0.0078 15.7 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0254) DnaJ PF00226.26 OAJ09187.1 - 3.7e-14 52.2 0.2 6.8e-14 51.3 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain PDGLE PF13190.1 OAJ09188.1 - 0.043 13.4 2.7 1.3 8.7 0.6 2.5 2 1 0 2 2 2 0 PDGLE domain MoaF PF10703.4 OAJ09188.1 - 0.16 10.9 1.2 0.22 10.5 0.8 1.1 1 0 0 1 1 1 0 Molybdenum cofactor biosynthesis protein F SCHIP-1 PF10148.4 OAJ09188.1 - 0.6 9.4 4.2 0.85 8.9 2.9 1.2 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 Macoilin PF09726.4 OAJ09188.1 - 1.1 7.3 6.1 1.2 7.2 4.2 1.1 1 0 0 1 1 1 0 Transmembrane protein UBN2 PF14223.1 OAJ09191.1 - 4.5e-05 23.2 0.0 0.00012 21.8 0.0 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ09191.1 - 7.1e-05 22.5 2.2 0.00017 21.3 1.5 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ09191.1 - 0.083 12.5 0.7 0.17 11.5 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 OAJ09191.1 - 0.23 10.9 2.1 0.26 10.7 0.1 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RVT_2 PF07727.9 OAJ09192.1 - 1.5e-86 289.4 0.0 1.9e-86 289.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAJ09192.1 - 0.16 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) IF4E PF01652.13 OAJ09196.1 - 9.3e-44 148.8 0.5 5.6e-43 146.3 0.4 2.0 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E STAG PF08514.6 OAJ09200.1 - 0.13 12.0 0.1 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 STAG domain Thymidylat_synt PF00303.14 OAJ09201.1 - 1.3e-94 316.1 0.0 1.9e-94 315.6 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.17 OAJ09201.1 - 1.6e-29 103.0 0.2 4.4e-29 101.6 0.1 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Macoilin PF09726.4 OAJ09205.1 - 0.026 12.8 21.8 0.073 11.3 15.1 1.7 1 1 0 1 1 1 0 Transmembrane protein SAPS PF04499.10 OAJ09205.1 - 2.7 6.5 15.1 0.019 13.6 2.0 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Fib_alpha PF08702.5 OAJ09205.1 - 3.4 7.7 10.5 11 6.0 7.0 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family GAS PF13851.1 OAJ09205.1 - 8.7 5.4 24.1 9.7 5.3 9.6 2.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding RVT_2 PF07727.9 OAJ09207.1 - 8.1e-86 286.9 0.0 1.2e-85 286.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09207.1 - 4e-20 72.1 0.0 8.3e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ09207.1 - 9.6e-07 28.3 0.0 2.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ09207.1 - 4.7e-05 22.8 0.3 0.00076 18.9 0.2 2.7 1 1 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ09207.1 - 0.017 14.4 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Flt3_lig PF02947.9 OAJ09207.1 - 0.21 11.4 0.0 0.4 10.5 0.0 1.3 1 0 0 1 1 1 0 flt3 ligand AF-4 PF05110.8 OAJ09207.1 - 0.27 9.0 2.4 0.43 8.3 1.7 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein UBN2 PF14223.1 OAJ09209.1 - 3.7e-06 26.7 0.0 8.7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ09209.1 - 0.00025 20.8 1.6 0.00061 19.5 1.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ09209.1 - 0.0023 17.4 0.1 0.006 16.0 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle rve PF00665.21 OAJ09219.1 - 2.1e-18 66.5 0.1 1.1e-17 64.2 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ09219.1 - 5.3e-14 52.0 0.0 1.2e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 OAJ09219.1 - 3.4e-05 23.5 0.7 0.0001 22.0 0.5 1.9 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 OAJ09219.1 - 0.00073 19.5 1.0 0.006 16.6 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein rve_3 PF13683.1 OAJ09219.1 - 0.00078 18.9 0.0 0.0022 17.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_2 PF13696.1 OAJ09219.1 - 0.0074 15.7 0.5 0.017 14.6 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 OAJ09221.1 - 1.1e-06 28.4 0.0 5.1e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ09221.1 - 7.7e-05 22.4 2.2 0.00017 21.3 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ09221.1 - 0.092 12.4 0.9 0.19 11.4 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 OAJ09221.1 - 0.66 9.5 2.9 0.49 9.9 0.2 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RVT_2 PF07727.9 OAJ09222.1 - 1.4e-14 53.7 0.0 2e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Metal_resist PF13801.1 OAJ09222.1 - 0.1 12.5 0.1 0.1 12.5 0.1 2.5 2 1 0 3 3 3 0 Heavy-metal resistance RVT_2 PF07727.9 OAJ09223.1 - 1e-53 181.8 0.0 1.4e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAJ09223.1 - 0.055 12.8 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Macin PF14865.1 OAJ09229.1 - 3.1 7.9 13.6 0.2 11.7 1.7 2.7 2 2 0 2 2 2 0 Macin ACOX PF01756.14 OAJ09232.1 - 1.5e-39 135.3 0.4 3.2e-39 134.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 OAJ09232.1 - 2.2e-22 79.6 0.1 4.6e-22 78.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 OAJ09232.1 - 8.6e-11 41.1 0.4 2.2e-10 39.8 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 OAJ09232.1 - 1.3e-05 25.3 0.5 0.00055 20.0 0.4 2.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAJ09232.1 - 0.11 13.1 0.0 0.45 11.1 0.0 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain TAP35_44 PF07265.6 OAJ09236.1 - 0.022 14.5 0.1 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 FAR1 PF03101.10 OAJ09240.1 - 8.3e-07 29.4 0.1 4.9e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 FAR1 DNA-binding domain MULE PF10551.4 OAJ09240.1 - 1.9e-06 27.9 0.0 5.6e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain FAM72 PF14976.1 OAJ09245.1 - 0.034 13.9 0.9 0.067 13.0 0.6 1.4 1 0 0 1 1 1 0 FAM72 protein ANAPC15 PF15243.1 OAJ09246.1 - 0.19 11.8 4.7 0.36 10.9 3.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Nop14 PF04147.7 OAJ09246.1 - 0.42 8.4 4.4 0.57 8.0 3.1 1.1 1 0 0 1 1 1 0 Nop14-like family COPI_C PF06957.6 OAJ09246.1 - 1.9 6.9 5.3 3.2 6.1 3.7 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Sigma70_ner PF04546.8 OAJ09246.1 - 3.8 7.0 4.9 8.6 5.9 3.4 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-RING_2 PF13639.1 OAJ09254.1 - 3.7e-08 33.0 11.9 5.8e-08 32.4 8.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAJ09254.1 - 8.5e-06 25.7 3.3 1.5e-05 25.0 2.3 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 OAJ09254.1 - 2.1e-05 24.0 9.7 3.5e-05 23.3 6.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ09254.1 - 0.00024 21.0 12.6 0.00038 20.4 8.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ09254.1 - 0.0088 15.7 10.4 0.013 15.1 7.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 OAJ09254.1 - 2 8.1 10.5 3.1 7.5 7.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CRCB PF02537.10 OAJ09255.1 - 2.2e-22 79.1 17.7 6e-15 55.1 3.8 2.6 2 0 0 2 2 2 2 CrcB-like protein U3snoRNP10 PF12397.3 OAJ09260.1 - 0.073 13.0 0.2 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 Asp_protease_2 PF13650.1 OAJ09261.1 - 0.00012 22.4 0.0 0.00028 21.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ09261.1 - 0.0042 16.8 0.1 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ09261.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 OAJ09261.1 - 0.0098 15.9 0.2 0.018 15.0 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein dUTPase PF00692.14 OAJ09261.1 - 0.027 13.9 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 dUTPase rve PF00665.21 OAJ09267.1 - 4.1e-14 52.7 0.0 1e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ09267.1 - 6.4e-08 32.2 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 OAJ09267.1 - 0.0088 15.5 0.0 0.029 13.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain IQ-like PF15157.1 OAJ09267.1 - 0.11 12.6 0.0 1.8 8.8 0.0 2.8 2 0 0 2 2 2 0 IQ-like zf-CCHC_4 PF14392.1 OAJ09268.1 - 0.27 10.9 2.1 0.62 9.7 0.9 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 OAJ09268.1 - 1.1 9.3 10.0 3.4 7.7 2.3 2.7 3 0 0 3 3 3 0 Zinc knuckle Bax1-I PF01027.15 OAJ09274.1 - 2.1e-34 118.9 7.8 3.6e-34 118.1 5.4 1.4 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CitT PF12431.3 OAJ09275.1 - 0.00041 20.3 0.3 5.2 7.2 0.0 4.1 3 0 0 3 3 3 2 Transcriptional regulator SHS2_Rpb7-N PF03876.12 OAJ09280.1 - 3.1e-06 27.2 0.0 6.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 YL1 PF05764.8 OAJ09280.1 - 0.0099 15.5 19.1 0.0099 15.5 13.2 2.3 2 0 0 2 2 2 1 YL1 nuclear protein Cwf_Cwc_15 PF04889.7 OAJ09280.1 - 2 8.0 29.4 0.054 13.1 14.5 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Glypican PF01153.14 OAJ09280.1 - 4.9 5.6 10.0 9.7 4.6 6.9 1.5 1 0 0 1 1 1 0 Glypican Alg14 PF08660.6 OAJ09281.1 - 7e-45 153.0 0.0 2.2e-44 151.4 0.0 1.7 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DUF1639 PF07797.9 OAJ09281.1 - 5.2 6.5 6.4 19 4.7 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) Atg14 PF10186.4 OAJ09282.1 - 4.3e-16 58.7 5.4 7.3e-16 57.9 3.7 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 ALO PF04030.9 OAJ09282.1 - 0.039 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Adeno_E3 PF06040.6 OAJ09282.1 - 0.14 12.1 0.1 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Adenovirus E3 protein Exonuc_VII_L PF02601.10 OAJ09282.1 - 0.18 10.9 6.4 0.29 10.2 4.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ribosomal_60s PF00428.14 OAJ09288.1 - 0.05 14.0 7.2 0.05 14.0 5.0 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein REV PF00424.13 OAJ09288.1 - 0.074 12.9 1.5 0.098 12.5 1.0 1.3 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) DUF563 PF04577.9 OAJ09288.1 - 0.23 11.3 1.4 0.29 11.0 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF563) Myc_N PF01056.13 OAJ09288.1 - 0.4 9.8 4.2 0.4 9.8 2.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Sporozoite_P67 PF05642.6 OAJ09288.1 - 0.72 7.6 2.7 0.75 7.5 1.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen WBS_methylT PF12589.3 OAJ09288.1 - 2.2 8.8 7.0 2.7 8.5 4.9 1.4 1 1 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome FAM176 PF14851.1 OAJ09288.1 - 9.3 5.9 8.9 10 5.7 6.2 1.1 1 0 0 1 1 1 0 FAM176 family Ras PF00071.17 OAJ09289.1 - 2.3e-33 114.8 0.5 4.7e-16 58.5 0.0 2.0 1 1 1 2 2 2 2 Ras family Miro PF08477.8 OAJ09289.1 - 1.1e-08 35.6 0.5 7.2e-07 29.7 0.1 2.1 1 1 1 2 2 2 1 Miro-like protein AAA_22 PF13401.1 OAJ09289.1 - 0.0026 17.8 0.0 0.0036 17.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain Arf PF00025.16 OAJ09289.1 - 0.01 15.0 0.0 0.68 9.1 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family MobB PF03205.9 OAJ09289.1 - 0.016 14.9 0.1 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 OAJ09289.1 - 0.018 14.9 0.2 0.026 14.4 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ09289.1 - 0.019 14.2 0.0 4.3 6.5 0.0 2.2 1 1 0 2 2 2 0 Ferrous iron transport protein B DUF258 PF03193.11 OAJ09289.1 - 0.071 12.3 0.2 0.11 11.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 OAJ09289.1 - 0.12 11.6 1.0 0.42 9.8 0.0 2.0 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit WD40 PF00400.27 OAJ09291.1 - 1.9e-63 208.2 26.5 5.9e-12 44.9 0.4 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 OAJ09291.1 - 2.2e-07 30.7 0.0 0.0014 18.3 0.0 3.6 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 OAJ09291.1 - 3.5e-07 28.7 8.6 0.026 12.6 0.2 5.6 2 1 3 5 5 5 4 Nucleoporin Nup120/160 DUF3312 PF11768.3 OAJ09291.1 - 0.041 12.0 0.0 0.083 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Orbi_VP6 PF01516.11 OAJ09291.1 - 0.18 10.8 3.5 0.36 9.8 2.4 1.4 1 0 0 1 1 1 0 Orbivirus helicase VP6 SR-25 PF10500.4 OAJ09291.1 - 0.25 10.7 5.6 0.57 9.6 3.9 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TMF_DNA_bd PF12329.3 OAJ09295.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 OAJ09295.1 - 0.17 11.6 0.1 0.41 10.4 0.0 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RVT_1 PF00078.22 OAJ09296.1 - 6.8e-19 68.0 0.0 1.7e-18 66.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09296.1 - 9.3e-16 58.0 0.0 1.9e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ09296.1 - 5.9e-07 29.9 0.1 1.6e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ09296.1 - 0.0012 18.5 0.1 0.0043 16.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ09296.1 - 0.14 12.0 0.0 0.54 10.1 0.0 1.9 1 1 0 1 1 1 0 Retroviral aspartyl protease DUF3712 PF12505.3 OAJ09303.1 - 9.6e-24 83.8 0.0 4.8e-12 46.0 0.0 4.7 4 0 0 4 4 4 4 Protein of unknown function (DUF3712) Pkinase PF00069.20 OAJ09309.1 - 2.5e-24 85.8 0.0 3.6e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ09309.1 - 3e-11 42.8 0.0 5.5e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RTC4 PF14474.1 OAJ09309.1 - 0.00045 20.1 0.0 0.0011 18.8 0.0 1.7 1 1 0 1 1 1 1 RTC4-like domain Kdo PF06293.9 OAJ09309.1 - 0.0072 15.4 0.1 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 OAJ09309.1 - 0.024 13.4 0.3 0.034 12.9 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 OAJ09309.1 - 0.23 10.7 1.1 0.4 10.0 0.2 1.8 2 1 0 2 2 2 0 RIO1 family DNA_ligase_A_C PF04679.10 OAJ09311.1 - 0.14 12.5 0.1 0.26 11.6 0.1 1.5 1 1 0 1 1 1 0 ATP dependent DNA ligase C terminal region AphA_like PF14557.1 OAJ09318.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator RAP1 PF07218.6 OAJ09325.1 - 1.5 6.8 9.1 2 6.4 6.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SKG6 PF08693.5 OAJ09326.1 - 0.0096 15.2 0.0 0.038 13.3 0.0 2.1 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1191 PF06697.7 OAJ09326.1 - 0.012 14.5 0.1 0.053 12.3 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1191) Syndecan PF01034.15 OAJ09326.1 - 0.047 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain ABC_membrane PF00664.18 OAJ09330.1 - 5.2e-61 206.4 25.0 5.2e-32 111.3 7.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ09330.1 - 3.7e-59 198.9 0.0 4.9e-29 101.3 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAJ09330.1 - 3.3e-16 59.1 2.4 6.8e-08 32.0 0.6 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 OAJ09330.1 - 1.8e-09 36.9 0.0 0.00061 19.0 0.0 2.6 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAJ09330.1 - 8e-09 36.3 0.3 0.00023 21.9 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAJ09330.1 - 3.5e-08 32.8 2.6 0.00059 19.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 OAJ09330.1 - 4.2e-08 33.5 0.1 0.21 11.4 0.0 4.3 3 1 0 4 4 4 2 AAA domain AAA_16 PF13191.1 OAJ09330.1 - 5.8e-07 29.6 1.0 0.075 13.0 0.1 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 OAJ09330.1 - 5.3e-06 26.6 0.3 0.06 13.4 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 OAJ09330.1 - 8e-06 26.1 0.1 0.006 16.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain ABC_ATPase PF09818.4 OAJ09330.1 - 3.3e-05 22.6 0.2 0.15 10.5 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.1 OAJ09330.1 - 6.9e-05 22.3 0.1 0.18 11.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 OAJ09330.1 - 8.9e-05 22.3 2.1 0.013 15.4 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_10 PF12846.2 OAJ09330.1 - 0.00034 20.1 4.5 1.3 8.4 0.1 3.5 3 0 0 3 3 3 2 AAA-like domain DUF3987 PF13148.1 OAJ09330.1 - 0.00047 18.8 1.3 0.00047 18.8 0.9 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3987) AAA_23 PF13476.1 OAJ09330.1 - 0.00061 20.1 2.6 0.038 14.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 OAJ09330.1 - 0.0014 18.5 4.0 0.54 10.2 0.2 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.24 OAJ09330.1 - 0.002 18.3 0.2 0.5 10.5 0.0 3.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 OAJ09330.1 - 0.0026 17.7 0.2 3 7.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 OAJ09330.1 - 0.0037 16.9 0.0 0.62 9.7 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 OAJ09330.1 - 0.008 15.6 0.0 3.6 7.0 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 OAJ09330.1 - 0.022 14.5 0.9 0.4 10.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 OAJ09330.1 - 0.024 13.7 2.6 0.3 10.1 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_14 PF13173.1 OAJ09330.1 - 0.042 13.7 0.0 0.31 10.9 0.0 2.4 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 OAJ09330.1 - 0.046 13.8 0.0 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 OAJ09330.1 - 0.085 12.5 0.0 3.3 7.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.18 OAJ09330.1 - 0.093 12.5 0.6 15 5.3 0.0 2.9 3 0 0 3 3 3 0 Dynamin family DUF2075 PF09848.4 OAJ09330.1 - 0.11 11.4 0.2 0.24 10.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_15 PF13175.1 OAJ09330.1 - 0.35 9.8 0.0 0.78 8.7 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain PIF1 PF05970.9 OAJ09335.1 - 2.8e-55 187.7 0.0 4.2e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ09335.1 - 1.7e-07 31.0 0.1 4.4e-07 29.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ09335.1 - 0.0011 18.6 0.1 0.0043 16.7 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 OAJ09335.1 - 0.0012 18.9 0.3 0.02 14.8 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.24 OAJ09335.1 - 0.0029 17.8 0.0 0.0093 16.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ09335.1 - 0.0087 16.1 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAJ09335.1 - 0.018 14.7 0.0 0.058 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 OAJ09335.1 - 0.022 14.3 0.0 0.25 10.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.4 OAJ09335.1 - 0.04 12.8 0.0 1.3 7.9 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 OAJ09335.1 - 0.041 12.5 0.0 0.12 10.9 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 OAJ09335.1 - 0.074 11.9 0.1 0.2 10.5 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.7 OAJ09335.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PIGA PF08288.7 OAJ09343.1 - 3.6e-41 139.4 0.0 7.4e-41 138.4 0.0 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 OAJ09343.1 - 1.7e-25 89.3 0.0 2.6e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 OAJ09343.1 - 1.2e-15 57.6 0.4 3.2e-15 56.2 0.3 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 OAJ09343.1 - 1.6e-15 57.5 2.5 5.9e-15 55.7 0.2 2.5 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 OAJ09343.1 - 2.3e-11 43.9 0.0 4.5e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 OAJ09343.1 - 0.00019 21.2 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 OAJ09343.1 - 0.00064 19.9 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Homeobox PF00046.24 OAJ09349.1 - 2.5e-14 52.6 0.5 6.6e-14 51.2 0.4 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 OAJ09349.1 - 0.0025 17.4 0.7 0.0069 16.0 0.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Peptidase_C8 PF03569.8 OAJ09349.1 - 0.071 12.4 0.2 0.11 11.7 0.2 1.3 1 0 0 1 1 1 0 Peptidase family C8 Sigma70_ner PF04546.8 OAJ09349.1 - 0.1 12.2 4.7 0.25 10.9 3.2 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Homeobox_KN PF05920.6 OAJ09350.1 - 0.0016 18.0 0.0 0.0062 16.2 0.0 2.1 1 1 0 1 1 1 1 Homeobox KN domain Ustilago_mating PF05722.7 OAJ09350.1 - 0.019 14.2 0.2 0.019 14.2 0.1 3.2 3 1 0 3 3 3 0 Ustilago B locus mating-type protein Transposase_21 PF02992.9 OAJ09354.1 - 0.041 12.9 0.0 0.16 10.9 0.0 1.9 2 0 0 2 2 2 0 Transposase family tnp2 Myb_DNA-bind_3 PF12776.2 OAJ09365.1 - 1.1e-17 64.4 1.5 1.9e-17 63.6 1.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ09365.1 - 4.3e-08 33.1 3.0 1.1e-07 31.8 2.1 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ09365.1 - 0.012 15.6 0.8 0.029 14.4 0.6 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Sigma70_ner PF04546.8 OAJ09365.1 - 4.3 6.8 7.1 5.8 6.4 0.9 2.4 2 1 0 2 2 2 0 Sigma-70, non-essential region AAA PF00004.24 OAJ09368.1 - 1.1e-40 138.9 0.0 2.1e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 OAJ09368.1 - 4.6e-26 90.4 0.1 2e-25 88.4 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 OAJ09368.1 - 1.7e-21 75.8 6.4 4.6e-21 74.4 4.5 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 OAJ09368.1 - 6.5e-05 23.0 0.4 0.0056 16.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ09368.1 - 7.1e-05 23.6 0.2 0.0003 21.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 OAJ09368.1 - 9.2e-05 21.3 0.4 0.0002 20.2 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 OAJ09368.1 - 9.4e-05 21.9 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 OAJ09368.1 - 0.00013 21.8 0.0 0.00032 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAJ09368.1 - 0.00018 21.2 0.0 0.00056 19.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 OAJ09368.1 - 0.00024 20.2 0.0 0.00043 19.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 OAJ09368.1 - 0.0003 20.6 0.2 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ09368.1 - 0.00084 19.3 0.4 0.011 15.7 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 OAJ09368.1 - 0.001 18.5 0.2 0.27 10.6 0.1 2.4 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 OAJ09368.1 - 0.0013 18.8 0.0 0.026 14.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.9 OAJ09368.1 - 0.0038 17.1 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 OAJ09368.1 - 0.01 14.7 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 OAJ09368.1 - 0.013 14.7 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 OAJ09368.1 - 0.042 12.9 0.0 5 6.1 0.0 2.3 1 1 1 2 2 2 0 KaiC Zeta_toxin PF06414.7 OAJ09368.1 - 0.043 12.9 0.1 0.64 9.0 0.0 2.3 1 1 1 2 2 2 0 Zeta toxin AAA_24 PF13479.1 OAJ09368.1 - 0.061 12.9 0.2 0.14 11.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.1 OAJ09368.1 - 0.069 12.9 0.0 0.26 11.0 0.0 2.0 2 0 0 2 2 1 0 Part of AAA domain PhoH PF02562.11 OAJ09368.1 - 0.085 12.0 0.6 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 OAJ09368.1 - 0.098 12.1 0.0 0.61 9.5 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 OAJ09368.1 - 0.1 12.0 0.7 0.93 8.8 0.1 2.5 4 0 0 4 4 3 0 AAA-like domain NACHT PF05729.7 OAJ09368.1 - 0.13 11.9 0.0 0.88 9.2 0.0 2.3 2 1 1 3 3 2 0 NACHT domain PEMT PF04191.8 OAJ09369.1 - 1.1e-20 73.7 1.2 1.1e-20 73.7 0.8 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase SNF2_N PF00176.18 OAJ09374.1 - 4.4e-27 94.6 0.0 7.2e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ09374.1 - 0.0055 16.5 0.0 0.017 15.0 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF2019 PF09450.5 OAJ09374.1 - 0.029 14.2 0.1 0.069 13.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) Aida_N PF08910.5 OAJ09374.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Aida N-terminus Med8 PF10232.4 OAJ09380.1 - 0.08 12.4 2.8 0.17 11.3 1.2 2.1 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 PPI_Ypi1 PF07491.6 OAJ09381.1 - 1.2e-25 88.9 1.7 7.9e-25 86.2 1.2 2.5 1 1 0 1 1 1 1 Protein phosphatase inhibitor Nop14 PF04147.7 OAJ09381.1 - 0.00088 17.3 0.7 0.00088 17.3 0.5 1.7 2 0 0 2 2 2 1 Nop14-like family CDC45 PF02724.9 OAJ09381.1 - 2.6 5.9 11.0 0.032 12.2 2.2 1.6 2 0 0 2 2 2 0 CDC45-like protein Histidinol_dh PF00815.15 OAJ09382.1 - 6.7e-154 512.4 1.0 1.8e-151 504.4 0.7 2.1 1 1 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 OAJ09382.1 - 2.4e-21 75.1 0.2 5.2e-21 74.0 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 OAJ09382.1 - 1.5e-11 44.3 0.9 1.5e-11 44.3 0.6 2.3 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 OAJ09382.1 - 0.0013 18.6 0.2 0.0027 17.6 0.2 1.5 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain DUF460 PF04312.8 OAJ09382.1 - 0.012 15.1 0.1 0.029 13.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF460) zf-UBR PF02207.15 OAJ09387.1 - 0.07 12.8 0.8 0.13 11.9 0.6 1.5 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) TF_Zn_Ribbon PF08271.7 OAJ09387.1 - 0.22 10.8 2.3 0.23 10.8 0.5 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding Elf1 PF05129.8 OAJ09387.1 - 0.41 10.3 7.9 0.096 12.3 2.6 2.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DUF2397 PF09660.5 OAJ09387.1 - 5.7 5.4 9.1 0.16 10.5 2.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2397) Acyl_transf_3 PF01757.17 OAJ09400.1 - 5.2e-17 61.6 44.1 1.6e-16 60.0 30.5 1.8 1 1 0 1 1 1 1 Acyltransferase family RVT_1 PF00078.22 OAJ09405.1 - 4.7e-17 62.0 0.0 8.3e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09405.1 - 2.8e-13 50.0 0.0 6.3e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ09405.1 - 0.012 16.0 0.0 0.033 14.6 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease EcKinase PF02958.15 OAJ09411.1 - 4.7e-20 71.9 0.0 3.6e-19 69.0 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 OAJ09411.1 - 1.6e-07 31.2 1.9 3.5e-07 30.2 1.3 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 OAJ09411.1 - 1.9e-07 30.0 0.0 3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) GCR1_C PF12550.3 OAJ09417.1 - 7e-06 25.8 0.1 1.5e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_23 PF13384.1 OAJ09417.1 - 0.00085 18.9 1.1 0.097 12.3 0.0 3.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 OAJ09417.1 - 0.0097 15.8 0.4 0.77 9.7 0.0 3.4 3 0 0 3 3 3 1 Transposase HTH_28 PF13518.1 OAJ09417.1 - 0.041 13.8 0.1 0.99 9.4 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain Phosphoesterase PF04185.9 OAJ09424.1 - 7.3e-25 87.9 2.2 9.8e-25 87.5 1.5 1.2 1 0 0 1 1 1 1 Phosphoesterase family Myb_DNA-bind_4 PF13837.1 OAJ09431.1 - 0.0022 18.1 2.3 0.0022 18.1 1.6 2.6 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ09431.1 - 0.06 13.4 0.1 0.18 11.9 0.1 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Cytochrom_C PF00034.16 OAJ09431.1 - 0.53 11.1 0.1 0.53 11.1 0.0 2.8 2 1 0 2 2 2 0 Cytochrome c DDE_Tnp_4 PF13359.1 OAJ09432.1 - 8.5e-20 70.9 0.0 2e-19 69.7 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 OAJ09439.1 - 0.00037 20.5 0.1 0.00079 19.5 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain Myb_DNA-bind_3 PF12776.2 OAJ09440.1 - 0.031 14.9 0.0 0.038 14.6 0.0 1.1 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain KAAG1 PF15354.1 OAJ09441.1 - 0.53 10.6 4.3 1 9.7 3.0 1.6 1 1 0 1 1 1 0 Kidney-associated antigen 1 DUF1522 PF07482.6 OAJ09441.1 - 0.76 9.9 4.1 0.86 9.7 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1522) PHD PF00628.24 OAJ09442.1 - 0.0033 17.0 10.7 0.0095 15.6 7.4 1.8 1 0 0 1 1 1 1 PHD-finger CDK2AP PF09806.4 OAJ09442.1 - 0.048 13.8 5.3 0.067 13.4 3.6 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Pex14_N PF04695.8 OAJ09442.1 - 0.57 10.2 7.7 1.1 9.3 5.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 OAJ09446.1 - 6.6 4.8 42.1 11 4.0 29.1 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Thioredoxin PF00085.15 OAJ09447.1 - 1.3e-61 204.6 0.3 1e-26 92.6 0.0 4.4 4 1 0 4 4 4 4 Thioredoxin Thioredoxin_6 PF13848.1 OAJ09447.1 - 1.1e-44 152.4 0.1 9e-38 129.9 0.2 3.4 2 2 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAJ09447.1 - 1.6e-15 56.9 0.3 0.0038 17.3 0.0 4.5 4 0 0 4 4 4 4 Thioredoxin-like Calsequestrin PF01216.12 OAJ09447.1 - 3.2e-14 52.5 0.9 5.1e-14 51.8 0.1 1.7 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_2 PF13098.1 OAJ09447.1 - 4e-13 49.5 4.9 0.00018 21.7 0.1 5.1 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 OAJ09447.1 - 6.2e-10 38.9 0.1 0.00051 20.0 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 OAJ09447.1 - 1.4e-06 28.0 1.7 0.019 14.6 0.0 3.4 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.5 OAJ09447.1 - 3.9e-05 23.2 2.4 0.25 10.8 0.0 3.5 3 0 0 3 3 3 2 Redoxin Thioredoxin_4 PF13462.1 OAJ09447.1 - 0.00019 21.4 3.3 0.14 12.1 0.0 3.5 3 1 0 3 3 3 2 Thioredoxin ERp29_N PF07912.8 OAJ09447.1 - 0.011 15.6 0.0 0.26 11.2 0.0 2.6 2 0 0 2 2 2 0 ERp29, N-terminal domain Thioredoxin_5 PF13743.1 OAJ09447.1 - 0.11 12.0 0.7 20 4.6 0.0 3.4 3 1 0 3 3 3 0 Thioredoxin Glutaredoxin PF00462.19 OAJ09447.1 - 0.12 12.3 0.4 25 4.9 0.0 3.7 4 1 0 4 4 4 0 Glutaredoxin Crust_neurohorm PF01147.12 OAJ09453.1 - 0.07 12.4 1.0 0.11 11.8 0.7 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Daxx PF03344.10 OAJ09453.1 - 0.094 11.1 25.2 0.096 11.1 17.5 1.0 1 0 0 1 1 1 0 Daxx Family Rsm1 PF08600.5 OAJ09453.1 - 0.096 12.5 0.4 0.14 12.0 0.3 1.4 1 1 0 1 1 1 0 Rsm1-like TraH_2 PF06871.6 OAJ09453.1 - 0.26 10.7 6.2 0.34 10.3 4.3 1.3 1 0 0 1 1 1 0 TraH_2 Nop14 PF04147.7 OAJ09453.1 - 1 7.1 28.7 0.98 7.2 19.9 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 OAJ09453.1 - 1.8 6.4 19.7 1.9 6.4 13.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 OAJ09453.1 - 2 7.0 32.0 2.2 6.9 22.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) YqfQ PF14181.1 OAJ09453.1 - 3.8 7.5 6.9 4.6 7.2 4.8 1.1 1 0 0 1 1 1 0 YqfQ-like protein Vfa1 PF08432.5 OAJ09453.1 - 6.2 6.8 13.0 7.1 6.6 9.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Cwf_Cwc_15 PF04889.7 OAJ09453.1 - 8 6.0 22.0 8.7 5.9 15.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TLP-20 PF06088.6 OAJ09453.1 - 9.2 5.8 9.1 13 5.4 6.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PsbH PF00737.15 OAJ09461.1 - 0.56 9.8 3.4 4.8 6.8 0.3 2.5 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Transposase_21 PF02992.9 OAJ09465.1 - 7.4e-18 64.4 0.1 1.4e-17 63.5 0.1 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ09465.1 - 0.099 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Pkinase PF00069.20 OAJ09468.1 - 1.5e-33 116.0 0.0 2.1e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ09468.1 - 7.3e-21 74.3 0.0 9.6e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ09468.1 - 0.00027 20.0 0.0 0.00038 19.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ09468.1 - 0.021 13.9 0.1 0.03 13.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ09468.1 - 0.056 13.1 0.2 0.12 12.0 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family SSP160 PF06933.6 OAJ09469.1 - 0.094 10.6 11.9 0.13 10.1 8.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tir_receptor_C PF07489.6 OAJ09469.1 - 0.56 9.9 9.3 0.91 9.2 6.5 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus RVT_1 PF00078.22 OAJ09473.1 - 2.5e-17 62.9 0.0 4.6e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09473.1 - 8.8e-15 54.8 0.0 2.7e-14 53.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ09473.1 - 0.00013 22.4 0.1 0.00035 20.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ09473.1 - 0.021 14.6 0.1 0.059 13.1 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ09473.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Ribosomal_S27 PF01599.14 OAJ09474.1 - 0.053 13.3 0.2 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S27a Complex1_LYR PF05347.10 OAJ09480.1 - 0.00012 21.8 3.3 0.00017 21.3 0.5 2.3 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAJ09480.1 - 0.0014 18.7 2.3 0.0033 17.6 0.4 2.2 2 0 0 2 2 2 1 Complex1_LYR-like F-box-like PF12937.2 OAJ09481.1 - 0.0017 18.0 0.5 0.089 12.5 0.1 2.9 2 0 0 2 2 2 2 F-box-like Atg14 PF10186.4 OAJ09485.1 - 0.28 10.1 8.2 0.48 9.3 5.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TSA PF03249.8 OAJ09485.1 - 0.3 9.5 9.4 0.49 8.8 6.5 1.2 1 0 0 1 1 1 0 Type specific antigen Pex14_N PF04695.8 OAJ09485.1 - 1.3 9.1 9.4 0.24 11.4 3.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nucleoplasmin PF03066.10 OAJ09486.1 - 0.36 10.3 5.8 0.79 9.2 4.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 OAJ09486.1 - 2 6.3 4.4 2.9 5.8 3.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 OAJ09486.1 - 2.2 7.8 6.9 0.79 9.2 2.5 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region NOA36 PF06524.7 OAJ09486.1 - 7.1 5.7 7.2 14 4.8 5.0 1.4 1 0 0 1 1 1 0 NOA36 protein MBOAT_2 PF13813.1 OAJ09493.1 - 9.3e-10 38.4 3.2 3.2e-05 23.8 0.7 2.8 1 1 1 2 2 2 2 Membrane bound O-acyl transferase family TPR_2 PF07719.12 OAJ09494.1 - 3.8e-29 98.2 13.8 6.2e-05 22.6 0.1 10.0 11 0 0 11 11 11 5 Tetratricopeptide repeat Apc3 PF12895.2 OAJ09494.1 - 4.7e-25 87.5 5.2 1.5e-09 37.8 0.3 6.0 5 1 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 OAJ09494.1 - 8.5e-25 86.1 12.9 1.3e-05 24.7 0.0 7.7 6 1 2 8 8 8 5 TPR repeat TPR_1 PF00515.23 OAJ09494.1 - 3.9e-21 73.7 10.0 0.0001 21.7 0.0 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ09494.1 - 1.9e-19 69.3 11.2 7.2e-06 25.8 0.0 8.2 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ09494.1 - 5.7e-16 58.7 25.8 6.3e-07 29.8 0.0 7.7 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ09494.1 - 2.5e-15 54.9 0.0 1.3e-05 24.5 0.1 7.4 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ09494.1 - 1.7e-14 52.7 2.8 1.5 9.2 0.0 8.0 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ09494.1 - 5.4e-14 51.4 23.4 0.0032 17.9 0.4 9.4 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ09494.1 - 3.8e-13 49.5 14.7 0.19 12.0 0.1 8.7 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ09494.1 - 2.6e-08 33.7 20.5 0.78 10.3 0.1 8.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ09494.1 - 5.9e-06 25.6 9.7 15 5.6 0.0 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ09494.1 - 4.8e-05 23.1 8.2 1.5 8.8 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ09494.1 - 0.025 14.4 11.2 0.73 9.7 0.1 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF3336 PF11815.3 OAJ09497.1 - 1.1e-43 148.2 1.8 1.8e-43 147.4 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 OAJ09497.1 - 2.5e-21 76.5 3.3 1.3e-20 74.2 0.1 3.2 2 2 0 2 2 2 1 Patatin-like phospholipase TadE PF07811.7 OAJ09497.1 - 0.27 11.1 2.5 0.68 9.8 1.7 1.6 1 0 0 1 1 1 0 TadE-like protein DDE_Tnp_4 PF13359.1 OAJ09502.1 - 1.1e-30 106.3 0.0 1.2e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ09502.1 - 7.2e-08 32.0 0.0 1.3e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 OAJ09502.1 - 1.6e-06 27.8 0.1 1.6e-05 24.5 0.1 2.0 1 1 0 1 1 1 1 Transposase DDE domain RVT_1 PF00078.22 OAJ09508.1 - 9e-27 93.8 0.0 1.6e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIA PF03153.8 OAJ09508.1 - 2.8 7.7 10.6 5.2 6.8 7.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit rve PF00665.21 OAJ09513.1 - 9.6e-14 51.5 0.0 1.1e-12 48.1 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ09513.1 - 2.7e-09 36.6 0.0 7.7e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 OAJ09513.1 - 2e-05 24.1 0.0 4.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.1 OAJ09513.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 OAJ09513.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.18 OAJ09513.1 - 0.38 10.7 1.7 0.76 9.8 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.12 OAJ09517.1 - 9.7e-17 60.8 1.0 2.3e-16 59.6 0.7 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAJ09517.1 - 0.0004 20.1 0.6 0.00068 19.4 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ09517.1 - 0.031 14.0 0.7 0.06 13.0 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Ldh_1_N PF00056.18 OAJ09520.1 - 0.0019 18.0 0.1 0.0028 17.5 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain RVT_2 PF07727.9 OAJ09521.1 - 4.3e-48 163.4 0.0 6.2e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09521.1 - 1.8e-20 73.2 0.0 3.5e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ09521.1 - 2.9e-05 23.6 0.0 5.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ09521.1 - 0.08 12.4 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain RVT_2 PF07727.9 OAJ09522.1 - 2.4e-19 69.2 0.0 3.2e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 OAJ09522.1 - 0.064 13.0 0.1 0.22 11.3 0.0 2.0 2 1 0 2 2 2 0 Reverse transcriptase-like SDH_beta PF03315.10 OAJ09522.1 - 0.1 12.6 0.2 0.73 9.8 0.1 2.2 1 1 0 1 1 1 0 Serine dehydratase beta chain UBN2_2 PF14227.1 OAJ09523.1 - 1.5e-09 37.3 0.0 2.1e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ09523.1 - 6.8e-05 22.6 0.0 9.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ09523.1 - 0.0012 18.6 2.6 0.002 17.9 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ09523.1 - 0.0022 17.4 0.6 0.0036 16.7 0.4 1.3 1 0 0 1 1 1 1 Zinc knuckle rve PF00665.21 OAJ09528.1 - 5.9e-16 58.6 0.0 1.9e-15 57.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ09528.1 - 7.8e-06 25.3 0.1 0.0012 18.2 0.0 2.6 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ09528.1 - 0.00073 19.9 1.0 0.0022 18.4 0.1 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ09528.1 - 0.014 15.2 0.2 0.041 13.7 0.1 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ09528.1 - 0.08 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.12 OAJ09529.1 - 0.12 12.4 0.1 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein ABC_membrane PF00664.18 OAJ09534.1 - 7.7e-57 192.7 28.6 2e-29 102.8 10.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ09534.1 - 2.5e-54 183.3 0.0 5.3e-31 107.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 OAJ09534.1 - 3.7e-09 36.9 0.1 0.18 11.7 0.0 4.3 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 OAJ09534.1 - 2.7e-07 30.0 2.5 0.014 14.6 0.0 3.9 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 OAJ09534.1 - 5.9e-07 29.0 0.3 0.064 12.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 OAJ09534.1 - 7.5e-07 28.5 0.2 0.0013 18.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 OAJ09534.1 - 4.8e-06 26.5 0.7 0.0063 16.4 0.1 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 OAJ09534.1 - 5.1e-06 26.9 5.2 0.19 12.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 OAJ09534.1 - 1.3e-05 25.6 1.5 0.035 14.6 0.1 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_16 PF13191.1 OAJ09534.1 - 2.9e-05 24.1 8.6 0.05 13.5 0.1 3.7 2 1 1 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 OAJ09534.1 - 7.2e-05 22.0 0.2 0.33 10.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 OAJ09534.1 - 9.3e-05 22.0 0.1 0.054 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain T2SE PF00437.15 OAJ09534.1 - 0.00014 20.8 0.0 0.0084 15.0 0.0 2.6 3 0 0 3 3 2 1 Type II/IV secretion system protein AAA_17 PF13207.1 OAJ09534.1 - 0.00022 22.0 0.3 0.2 12.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 OAJ09534.1 - 0.0005 19.9 0.6 0.0016 18.3 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_14 PF13173.1 OAJ09534.1 - 0.0013 18.6 0.2 15 5.5 0.0 4.1 4 0 0 4 4 4 0 AAA domain Zeta_toxin PF06414.7 OAJ09534.1 - 0.0015 17.6 0.6 0.4 9.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.9 OAJ09534.1 - 0.002 17.8 1.2 0.3 10.7 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 OAJ09534.1 - 0.0021 18.1 0.8 2.1 8.5 0.0 3.2 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 OAJ09534.1 - 0.006 16.2 1.3 3.1 7.4 0.1 2.6 2 0 0 2 2 2 2 NACHT domain Dynamin_N PF00350.18 OAJ09534.1 - 0.0066 16.2 5.1 0.086 12.6 0.0 3.0 3 0 0 3 3 3 1 Dynamin family FtsK_SpoIIIE PF01580.13 OAJ09534.1 - 0.013 15.0 0.2 0.053 12.9 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 OAJ09534.1 - 0.016 15.0 1.4 8.1 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 OAJ09534.1 - 0.049 13.0 1.8 1.9 7.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 OAJ09534.1 - 0.055 13.7 2.8 0.75 10.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 OAJ09534.1 - 0.07 13.3 0.1 13 5.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase TrwB_AAD_bind PF10412.4 OAJ09534.1 - 0.079 11.5 1.0 0.61 8.6 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.17 OAJ09534.1 - 0.083 11.7 0.5 5.5 5.7 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.20 OAJ09534.1 - 0.11 11.9 0.1 6.8 6.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 OAJ09534.1 - 0.12 12.1 4.1 0.71 9.5 0.0 3.3 5 1 0 5 5 2 0 Archaeal ATPase Adeno_IVa2 PF02456.10 OAJ09534.1 - 0.17 10.4 0.0 6.9 5.2 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA PF00004.24 OAJ09534.1 - 0.2 11.8 1.3 22 5.2 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 OAJ09534.1 - 0.2 11.2 1.2 9.1 5.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 OAJ09534.1 - 0.37 10.2 0.7 18 4.8 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.4 OAJ09534.1 - 0.4 9.1 3.3 9.3 4.7 0.1 3.6 4 0 0 4 4 4 0 Predicted ATPase of the ABC class Viral_helicase1 PF01443.13 OAJ09534.1 - 0.46 9.9 0.5 13 5.2 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DIM PF08194.7 OAJ09534.1 - 3.5 7.6 5.0 1.4 8.9 0.4 2.7 2 0 0 2 2 1 0 DIM protein FAR1 PF03101.10 OAJ09539.1 - 8.8e-07 29.3 1.0 1.3e-06 28.7 0.7 1.2 1 0 0 1 1 1 1 FAR1 DNA-binding domain 2OG-FeII_Oxy_3 PF13640.1 OAJ09543.1 - 0.00032 21.1 0.3 0.00089 19.7 0.2 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ09543.1 - 0.017 15.3 0.1 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Clostridium_P47 PF06597.6 OAJ09543.1 - 0.062 11.8 0.0 0.097 11.1 0.0 1.1 1 0 0 1 1 1 0 Clostridium P-47 protein Ricin_B_lectin PF00652.17 OAJ09544.1 - 0.068 13.1 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Phage_lambd_GpG PF06894.6 OAJ09553.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage lambda minor tail protein (GpG) Transposase_21 PF02992.9 OAJ09554.1 - 2.1e-07 30.2 0.0 2.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 zf-RVT PF13966.1 OAJ09558.1 - 0.00026 21.2 0.5 0.00059 20.1 0.4 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.19 OAJ09558.1 - 0.00027 21.2 0.1 0.00065 20.0 0.0 1.7 2 0 0 2 2 2 1 RNase H HypA PF01155.14 OAJ09558.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Ribosomal_60s PF00428.14 OAJ09558.1 - 3.7 8.0 15.1 2.5 8.5 0.9 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein RVT_1 PF00078.22 OAJ09559.1 - 2.7e-24 85.7 0.0 4.9e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ09559.1 - 2.3e-17 62.6 0.2 5.6e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ09559.1 - 1.5e-06 28.3 0.6 4.2e-06 26.8 0.4 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AhpC-TSA_2 PF13911.1 OAJ09565.1 - 5.5e-14 52.0 0.0 9.5e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 OAJ09565.1 - 2.1e-08 33.8 0.0 4.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAJ09565.1 - 4.5e-08 32.8 0.0 8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DUF899 PF05988.7 OAJ09565.1 - 0.052 12.9 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) CDO_I PF05995.7 OAJ09570.1 - 7.3e-07 28.5 0.1 1.4e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 OAJ09570.1 - 0.0076 15.6 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) Phospho_p8 PF10195.4 OAJ09571.1 - 0.022 14.6 0.3 0.022 14.6 0.2 2.3 2 0 0 2 2 2 0 DNA-binding nuclear phosphoprotein p8 Apt1 PF10351.4 OAJ09571.1 - 2.9 6.6 17.1 6 5.6 11.8 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.4 OAJ09571.1 - 5.6 5.1 20.9 0.062 11.5 9.4 1.3 2 0 0 2 2 2 0 Transmembrane protein Hid1 PF12722.2 OAJ09571.1 - 6.7 4.2 10.9 8.8 3.8 7.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM60A PF15396.1 OAJ09571.1 - 8.6 6.0 18.5 0.54 9.9 7.7 2.2 2 0 0 2 2 2 0 Protein Family FAM60A FLO_LFY PF01698.11 OAJ09571.1 - 8.7 5.0 13.9 6.6 5.4 0.3 2.2 2 0 0 2 2 2 0 Floricaula / Leafy protein Transposase_21 PF02992.9 OAJ09574.1 - 5.4e-19 68.1 0.0 1.2e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 GEMIN8 PF15348.1 OAJ09574.1 - 0.087 12.8 2.1 0.21 11.6 1.5 1.6 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Ferric_reduct PF01794.14 OAJ09578.1 - 7.3e-13 48.7 3.2 1.4e-12 47.7 2.2 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component DUF1446 PF07287.6 OAJ09578.1 - 0.051 12.0 2.7 0.084 11.3 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1446) Hexapep PF00132.19 OAJ09578.1 - 0.068 12.7 1.2 0.29 10.7 0.3 2.3 1 1 1 2 2 2 0 Bacterial transferase hexapeptide (six repeats) Nop14 PF04147.7 OAJ09578.1 - 0.17 9.8 0.6 0.23 9.3 0.4 1.1 1 0 0 1 1 1 0 Nop14-like family NTP_transferase PF00483.18 OAJ09578.1 - 0.19 11.0 0.0 0.74 9.0 0.0 1.8 2 0 0 2 2 2 0 Nucleotidyl transferase NAD_binding_6 PF08030.7 OAJ09579.1 - 4.2e-12 46.2 0.0 6.8e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 OAJ09579.1 - 1.5e-08 34.4 0.0 4.1e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain Methyltransf_31 PF13847.1 OAJ09580.1 - 4.7e-12 45.7 0.3 7.9e-12 45.0 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 OAJ09580.1 - 2.1e-10 40.2 0.1 3.7e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 OAJ09580.1 - 2.3e-10 41.0 0.4 5.7e-10 39.7 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ09580.1 - 7.2e-09 35.5 0.0 2e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ09580.1 - 6.8e-08 32.5 0.0 1.8e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ09580.1 - 1.4e-07 31.9 0.0 3.2e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAJ09580.1 - 4.2e-07 29.3 0.0 5.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 OAJ09580.1 - 5.5e-06 25.8 0.1 1.2e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.11 OAJ09580.1 - 1e-05 24.7 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.6 OAJ09580.1 - 1.1e-05 24.3 0.0 1.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 OAJ09580.1 - 2.6e-05 24.5 0.0 5.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ09580.1 - 0.00011 22.5 0.1 0.00026 21.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 OAJ09580.1 - 0.0014 18.6 0.2 0.0022 18.0 0.2 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 OAJ09580.1 - 0.0034 16.9 0.0 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 OAJ09580.1 - 0.0041 16.5 0.1 0.0066 15.9 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 OAJ09580.1 - 0.0072 15.9 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 OAJ09580.1 - 0.021 13.9 0.3 0.052 12.6 0.1 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MetW PF07021.7 OAJ09580.1 - 0.041 13.2 0.1 0.07 12.4 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 OAJ09580.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 OAJ09580.1 - 0.07 12.2 1.8 0.16 11.1 0.4 2.2 2 1 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_4 PF02390.12 OAJ09580.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase EAL PF00563.15 OAJ09584.1 - 1.9e-73 246.8 1.7 1.2e-72 244.2 0.3 2.4 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.16 OAJ09584.1 - 4.5e-51 172.6 0.0 8.9e-51 171.6 0.0 1.5 1 0 0 1 1 1 1 GGDEF domain PAS_9 PF13426.1 OAJ09584.1 - 9.9e-40 135.1 0.0 8.8e-25 87.0 0.0 4.5 3 1 1 4 4 4 3 PAS domain Response_reg PF00072.19 OAJ09584.1 - 3.2e-37 126.9 0.5 5.5e-22 77.8 0.0 2.9 2 0 0 2 2 2 2 Response regulator receiver domain PAS_8 PF13188.1 OAJ09584.1 - 1.2e-22 78.8 1.0 4.4e-08 32.6 0.0 3.9 3 0 0 3 3 3 3 PAS domain PAS PF00989.19 OAJ09584.1 - 2.2e-21 75.7 0.2 1.8e-08 34.1 0.0 4.5 3 1 1 4 4 4 3 PAS fold PAS_4 PF08448.5 OAJ09584.1 - 4e-20 71.8 2.1 5.8e-08 32.7 0.0 3.8 4 0 0 4 4 4 3 PAS fold PAS_3 PF08447.6 OAJ09584.1 - 6.6e-12 45.3 0.2 1.2e-07 31.6 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS_7 PF12860.2 OAJ09584.1 - 0.037 14.0 0.1 3 7.8 0.0 3.1 2 0 0 2 2 2 0 PAS fold MEKHLA PF08670.6 OAJ09584.1 - 0.044 13.3 0.1 1 8.9 0.0 2.7 2 0 0 2 2 2 0 MEKHLA domain HATPase_c PF02518.21 OAJ09585.1 - 9e-27 93.0 0.0 1.9e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 OAJ09585.1 - 5.7e-08 32.6 0.2 3e-07 30.3 0.1 2.3 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 OAJ09585.1 - 1.9e-06 27.6 0.1 7e-06 25.8 0.0 2.1 2 1 1 3 3 3 1 PAS fold PAS_9 PF13426.1 OAJ09585.1 - 5.3e-06 26.7 0.0 2.4e-05 24.6 0.0 2.2 2 1 0 2 2 2 1 PAS domain PAS_4 PF08448.5 OAJ09585.1 - 3.6e-05 23.7 0.0 0.00061 19.7 0.0 2.7 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.1 OAJ09585.1 - 0.00017 21.2 0.0 0.00069 19.3 0.0 2.1 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.1 OAJ09585.1 - 0.025 14.2 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.1 OAJ09585.1 - 0.025 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 GHKL domain Ecm29 PF13001.2 OAJ09585.1 - 0.065 11.7 0.1 0.085 11.3 0.1 1.1 1 0 0 1 1 1 0 Proteasome stabiliser PAS_10 PF13596.1 OAJ09585.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 PAS domain HATPase_c PF02518.21 OAJ09586.1 - 4.6e-28 97.1 0.0 7.3e-28 96.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.1 OAJ09586.1 - 0.00038 20.1 0.0 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.1 OAJ09586.1 - 0.00098 18.9 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 OAJ09586.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ApoLp-III PF07464.6 OAJ09586.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) HisKA PF00512.20 OAJ09586.1 - 0.25 11.3 1.1 0.91 9.5 0.0 2.3 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 OAJ09587.1 - 1.4e-18 66.8 0.1 1.6e-18 66.7 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain GFO_IDH_MocA PF01408.17 OAJ09587.1 - 0.031 14.7 0.1 0.035 14.6 0.0 1.2 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold HisG_C PF08029.6 OAJ09587.1 - 0.07 13.0 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 HisG, C-terminal domain CoA_binding_2 PF13380.1 OAJ09587.1 - 0.075 13.1 0.1 0.09 12.9 0.1 1.1 1 0 0 1 1 1 0 CoA binding domain CheX PF13690.1 OAJ09588.1 - 0.0016 18.2 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Chemotaxis phosphatase CheX DUF2235 PF09994.4 OAJ09597.1 - 4.8e-33 114.7 0.0 7.7e-32 110.7 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Pkinase PF00069.20 OAJ09605.1 - 3e-59 200.3 0.0 4.2e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ09605.1 - 3.9e-31 108.0 0.0 5.2e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ09605.1 - 0.0053 15.7 0.0 0.008 15.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like MitMem_reg PF13012.1 OAJ09606.1 - 2e-33 114.9 0.1 5.7e-33 113.4 0.0 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 OAJ09606.1 - 3e-27 94.6 0.0 4.9e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PQ-loop PF04193.9 OAJ09611.1 - 9.5e-36 121.1 6.3 9.5e-18 63.5 0.9 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 OAJ09611.1 - 0.045 13.6 0.4 0.045 13.6 0.2 2.2 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange GATase_7 PF13537.1 OAJ09612.1 - 5.7e-38 129.4 0.0 9.3e-38 128.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Asn_synthase PF00733.16 OAJ09612.1 - 5.8e-33 114.4 0.0 1.1e-32 113.5 0.0 1.4 1 1 0 1 1 1 1 Asparagine synthase GATase_6 PF13522.1 OAJ09612.1 - 5.7e-30 103.9 0.0 4.7e-29 101.0 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 OAJ09612.1 - 7e-07 28.2 0.0 0.0017 17.1 0.0 2.8 1 1 2 3 3 3 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 OAJ09612.1 - 3.4e-06 26.4 0.0 9e-06 25.0 0.0 1.7 2 0 0 2 2 2 1 Aluminium induced protein NAD_synthase PF02540.12 OAJ09612.1 - 0.033 13.1 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 NAD synthase QueC PF06508.8 OAJ09612.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC DUF1933 PF09147.5 OAJ09612.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) RVT_1 PF00078.22 OAJ09616.1 - 1.1e-16 60.8 0.0 2.2e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09616.1 - 5.3e-13 49.1 0.0 1.6e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ09616.1 - 0.00026 21.4 0.0 0.00085 19.7 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ09616.1 - 0.024 14.5 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease dUTPase PF00692.14 OAJ09616.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 dUTPase PIF1 PF05970.9 OAJ09618.1 - 4.6e-14 52.1 0.6 4.4e-06 25.8 0.1 3.1 3 1 1 4 4 4 2 PIF1-like helicase AAA_30 PF13604.1 OAJ09618.1 - 1.6e-09 37.5 5.1 2.1e-07 30.7 0.1 3.6 3 1 0 4 4 4 1 AAA domain AAA_19 PF13245.1 OAJ09618.1 - 2.9e-07 30.1 0.8 1.4e-06 27.9 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 OAJ09618.1 - 0.003 17.5 2.2 0.0039 17.1 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_11 PF13086.1 OAJ09618.1 - 0.028 14.0 0.1 6.7 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Torsin PF06309.6 OAJ09618.1 - 0.045 13.6 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 Torsin Sigma54_activat PF00158.21 OAJ09618.1 - 0.048 13.1 0.1 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ09618.1 - 0.053 13.2 0.2 0.57 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 OAJ09618.1 - 0.059 13.5 0.3 0.37 10.9 0.1 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ09618.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Helitron_like_N PF14214.1 OAJ09619.1 - 1.8e-10 40.8 0.6 3.3e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus DDE_1 PF03184.14 OAJ09625.1 - 5.6e-34 117.1 0.0 1.2e-33 116.0 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAJ09625.1 - 4e-09 36.1 0.0 1.1e-07 31.5 0.0 2.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain VASP_tetra PF08776.6 OAJ09625.1 - 0.07 12.4 0.8 0.16 11.3 0.6 1.6 1 0 0 1 1 1 0 VASP tetramerisation domain UDP-g_GGTase PF06427.6 OAJ09632.1 - 2.2e-53 180.7 0.0 3.7e-53 179.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 OAJ09632.1 - 5.4e-07 29.2 0.1 1.1e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 PspA_IM30 PF04012.7 OAJ09632.1 - 0.16 11.3 2.4 0.35 10.1 0.3 2.1 2 0 0 2 2 2 0 PspA/IM30 family DBD_Tnp_Mut PF03108.10 OAJ09637.1 - 3.2e-12 45.8 0.1 4.9e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 MuDR family transposase WH1 PF00568.18 OAJ09637.1 - 0.053 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 WH1 domain DUF4142 PF13628.1 OAJ09637.1 - 0.086 12.8 0.1 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) DDE_3 PF13358.1 OAJ09642.1 - 3.8e-34 117.5 0.0 6.5e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 OAJ09642.1 - 9.4e-07 28.1 0.0 1.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 OAJ09642.1 - 2.3e-06 27.7 0.0 6.5e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain HTH_32 PF13565.1 OAJ09642.1 - 0.00054 20.7 0.1 0.0016 19.1 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain DDE_Tnp_ISAZ013 PF07592.6 OAJ09642.1 - 0.079 11.6 0.0 0.27 9.9 0.0 1.7 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain HTH_33 PF13592.1 OAJ09642.1 - 0.082 12.4 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix TIP49 PF06068.8 OAJ09644.1 - 4.5e-176 585.4 0.0 6.5e-176 584.9 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 OAJ09644.1 - 1.9e-10 41.0 0.1 3.8e-06 27.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 OAJ09644.1 - 4.7e-09 35.6 0.6 1.8e-05 23.9 0.0 2.8 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 OAJ09644.1 - 5.2e-07 29.8 0.2 0.056 13.5 0.1 2.7 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAJ09644.1 - 3.5e-05 23.8 0.0 0.0015 18.5 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 OAJ09644.1 - 4.2e-05 23.2 0.2 0.014 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 OAJ09644.1 - 5.3e-05 22.9 0.1 0.0003 20.4 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 OAJ09644.1 - 0.0002 21.3 0.1 0.00038 20.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAJ09644.1 - 0.00027 20.3 0.0 0.00055 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 OAJ09644.1 - 0.0033 16.6 0.1 0.24 10.5 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 OAJ09644.1 - 0.0036 16.7 0.2 0.012 14.9 0.1 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 OAJ09644.1 - 0.011 15.6 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAJ09644.1 - 0.017 14.7 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 OAJ09644.1 - 0.018 14.9 0.0 5.1 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 OAJ09644.1 - 0.019 14.4 0.1 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.4 OAJ09644.1 - 0.034 13.1 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 OAJ09644.1 - 0.056 12.5 0.4 0.12 11.4 0.3 1.5 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 OAJ09644.1 - 0.068 12.8 0.1 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 OAJ09644.1 - 0.068 13.9 0.0 0.22 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.10 OAJ09644.1 - 0.085 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DEAD PF00270.24 OAJ09647.1 - 1.3e-42 145.1 0.1 2.3e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ09647.1 - 1.7e-20 72.6 0.0 3.3e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 OAJ09647.1 - 3.9e-20 71.1 0.2 8.9e-20 70.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) zf-AN1 PF01428.11 OAJ09648.1 - 4.1e-18 64.9 28.0 1e-09 38.1 6.6 2.4 2 0 0 2 2 2 2 AN1-like Zinc finger SOG2 PF10428.4 OAJ09648.1 - 0.15 10.6 2.9 0.21 10.2 2.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein UcrQ PF02939.11 OAJ09654.1 - 5.6e-19 67.7 4.2 7e-19 67.4 2.9 1.1 1 0 0 1 1 1 1 UcrQ family UQ_con PF00179.21 OAJ09656.1 - 4e-22 78.1 0.0 4.7e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ09656.1 - 0.017 14.8 0.0 0.034 13.9 0.0 1.5 1 1 1 2 2 2 0 Prokaryotic E2 family B Dimer_Tnp_hAT PF05699.9 OAJ09661.1 - 2.2e-14 52.8 0.0 4.8e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CorA PF01544.13 OAJ09661.1 - 0.16 11.0 2.7 0.28 10.1 1.9 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CobT PF06213.7 OAJ09661.1 - 0.19 10.8 14.6 0.5 9.4 10.1 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pkinase PF00069.20 OAJ09662.1 - 1.2e-36 126.1 0.0 1.7e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ09662.1 - 4e-16 58.8 0.0 6.8e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ09662.1 - 4.7e-07 29.0 0.0 8e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 OAJ09667.1 - 2.4e-65 220.2 0.0 2.8e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ09667.1 - 4.4e-33 114.4 0.0 5.6e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ09667.1 - 0.00015 20.8 0.0 0.0002 20.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ09667.1 - 0.04 12.9 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ09667.1 - 0.68 9.6 5.6 0.41 10.3 1.8 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF1970 PF09301.5 OAJ09667.1 - 0.96 9.5 5.6 1.8 8.6 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) DUF1049 PF06305.6 OAJ09668.1 - 0.055 12.9 0.5 0.1 12.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Daxx PF03344.10 OAJ09668.1 - 2.2 6.6 4.4 4.8 5.5 3.1 1.5 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 OAJ09668.1 - 3.3 5.5 4.1 4.6 5.0 2.9 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 OAJ09668.1 - 4 6.9 10.6 8.6 5.8 7.4 1.5 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 OAJ09668.1 - 9.9 5.3 5.5 17 4.5 3.8 1.3 1 0 0 1 1 1 0 NOA36 protein FAD_binding_4 PF01565.18 OAJ09673.1 - 1.2e-22 79.8 1.7 3.8e-22 78.2 1.0 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 OAJ09673.1 - 0.0044 16.8 0.3 0.0089 15.9 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like CMS1 PF14617.1 OAJ09674.1 - 1.5e-19 70.1 2.9 2.1e-09 36.8 0.3 4.2 2 2 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit Gly-zipper_OmpA PF13436.1 OAJ09674.1 - 0.11 12.1 6.1 0.26 10.9 4.2 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Serglycin PF04360.7 OAJ09674.1 - 0.15 11.7 0.7 0.24 11.1 0.5 1.3 1 0 0 1 1 1 0 Serglycin OCC1 PF15506.1 OAJ09674.1 - 0.63 9.9 7.3 2.5 8.0 5.0 2.1 1 0 0 1 1 1 0 OCC1 family BRF1 PF07741.8 OAJ09674.1 - 8.1 6.7 7.9 5.2 7.3 0.4 3.0 3 0 0 3 3 3 0 Brf1-like TBP-binding domain DUF4504 PF14953.1 OAJ09675.1 - 1.2e-07 31.3 0.0 5.9e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4504) LTD PF00932.14 OAJ09675.1 - 0.056 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Lamin Tail Domain Sec7 PF01369.15 OAJ09680.1 - 6.7e-35 120.4 0.0 1.1e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 OAJ09680.1 - 8.8e-09 35.5 0.0 1.5e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 OAJ09680.1 - 0.0028 17.8 0.6 0.0089 16.1 0.2 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain MSP1_C PF07462.6 OAJ09680.1 - 5 5.3 2.1 15 3.8 1.5 1.8 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Glycolipid_bind PF06475.6 OAJ09681.1 - 0.1 11.7 0.1 0.31 10.1 0.0 1.7 2 0 0 2 2 2 0 Putative glycolipid-binding eIF2A PF08662.6 OAJ09687.1 - 4.2e-41 140.8 0.7 1.9e-36 125.6 0.1 4.4 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 OAJ09687.1 - 6.6e-06 25.6 0.1 1.5e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ09687.1 - 8.6e-06 25.6 0.1 2.3e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ09687.1 - 7.2e-05 22.5 0.1 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 OAJ09687.1 - 0.00058 19.6 7.1 0.2 11.6 0.0 5.4 6 0 0 6 6 6 1 WD domain, G-beta repeat DPPIV_N PF00930.16 OAJ09687.1 - 0.031 12.8 0.1 2.4 6.6 0.0 3.2 3 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region GCV_T PF01571.16 OAJ09688.1 - 3.1e-14 52.8 0.0 2.5e-13 49.8 0.0 2.0 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 OAJ09688.1 - 0.00092 19.1 0.0 0.0026 17.7 0.0 1.9 1 1 1 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain Sad1_UNC PF07738.8 OAJ09693.1 - 1.3e-11 44.4 0.0 0.00019 21.2 0.0 3.1 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal Mer2 PF09074.5 OAJ09693.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Mer2 SNARE PF05739.14 OAJ09693.1 - 0.1 12.3 1.2 0.26 10.9 0.9 1.8 1 0 0 1 1 1 0 SNARE domain Ebola_NP PF05505.7 OAJ09693.1 - 3.9 5.4 6.5 6.6 4.6 4.5 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein BOP1NT PF08145.7 OAJ09694.1 - 9.3e-103 343.4 1.5 1.4e-102 342.9 1.1 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 OAJ09694.1 - 1.2e-26 91.5 1.2 4.2e-05 23.2 0.0 7.4 8 0 0 8 8 8 4 WD domain, G-beta repeat Daxx PF03344.10 OAJ09694.1 - 1.9 6.8 20.4 3 6.2 14.1 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 OAJ09694.1 - 5.6 4.7 28.1 8.2 4.2 19.5 1.1 1 0 0 1 1 1 0 Nop14-like family Actin PF00022.14 OAJ09695.1 - 5.7e-29 100.7 0.0 1.3e-28 99.5 0.0 1.5 1 1 0 1 1 1 1 Actin ABC_membrane PF00664.18 OAJ09698.1 - 3.4e-09 36.5 2.9 3.4e-09 36.5 2.0 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ09700.1 - 5.1e-30 104.5 0.0 8.1e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 OAJ09700.1 - 2.8e-16 59.7 12.4 3.5e-08 33.2 1.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 OAJ09700.1 - 3.7e-08 32.8 0.8 6.2e-06 25.5 0.5 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 OAJ09700.1 - 2.1e-05 24.5 2.6 3.3e-05 23.9 1.1 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 OAJ09700.1 - 8.2e-05 22.7 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 OAJ09700.1 - 0.00051 19.9 0.4 0.012 15.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 OAJ09700.1 - 0.00084 18.8 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_25 PF13481.1 OAJ09700.1 - 0.002 17.5 0.7 0.0081 15.5 0.5 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ09700.1 - 0.0039 17.3 0.2 0.013 15.6 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 OAJ09700.1 - 0.01 15.3 0.0 0.027 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 OAJ09700.1 - 0.022 14.3 0.1 4 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 OAJ09700.1 - 0.031 12.9 0.1 0.053 12.1 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 OAJ09700.1 - 0.041 12.7 0.0 0.079 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 OAJ09700.1 - 0.074 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAJ09700.1 - 0.086 13.1 0.3 0.15 12.3 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 OAJ09700.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 OAJ09700.1 - 0.13 11.6 0.1 0.43 9.9 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain NTPase_1 PF03266.10 OAJ09700.1 - 0.13 11.9 0.4 1 9.0 0.0 2.1 2 0 0 2 2 2 0 NTPase MMR_HSR1 PF01926.18 OAJ09700.1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.17 OAJ09700.1 - 0.32 9.8 0.9 7.2 5.3 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.22 OAJ09701.1 - 2.1e-13 50.7 0.0 4.7e-13 49.6 0.0 1.6 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 OAJ09701.1 - 0.0037 17.1 0.3 0.016 15.0 0.1 2.0 2 0 0 2 2 2 1 Dynamin family SbcCD_C PF13558.1 OAJ09701.1 - 0.044 13.7 0.4 0.22 11.4 0.3 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MTHFR PF02219.12 OAJ09705.1 - 3.7e-94 315.0 0.0 4.1e-84 282.0 0.0 3.3 3 0 0 3 3 3 3 Methylenetetrahydrofolate reductase Ala_racemase_N PF01168.15 OAJ09705.1 - 1.5e-26 93.2 1.6 2.5e-24 86.0 1.1 2.4 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Cytochrom_B561 PF03188.11 OAJ09705.1 - 3.7e-08 33.3 13.0 7.2e-08 32.3 9.0 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 ECH PF00378.15 OAJ09706.1 - 1.1e-18 67.3 0.0 1.3e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_C48 PF02902.14 OAJ09710.1 - 1.3e-12 47.8 0.1 1.3e-12 47.8 0.1 2.1 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain SWIM PF04434.12 OAJ09710.1 - 0.051 13.0 0.3 0.1 12.1 0.2 1.5 1 0 0 1 1 1 0 SWIM zinc finger Pkinase PF00069.20 OAJ09715.1 - 6.5e-63 212.3 0.0 6e-62 209.1 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ09715.1 - 2e-34 118.8 0.0 4.3e-27 94.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ09715.1 - 1.1e-06 27.8 0.1 0.0012 17.8 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Seadorna_VP7 PF07387.6 OAJ09715.1 - 0.00095 18.0 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 OAJ09715.1 - 0.002 17.9 0.8 0.02 14.5 0.0 3.0 4 0 0 4 4 4 1 Phosphotransferase enzyme family Palm_thioest PF02089.10 OAJ09716.1 - 2.9e-64 216.7 0.0 3.3e-51 173.8 0.0 2.0 2 0 0 2 2 2 2 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 OAJ09716.1 - 5.4e-05 23.1 0.0 8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ09716.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Helitron_like_N PF14214.1 OAJ09722.1 - 3.7e-48 163.6 0.1 2.9e-47 160.7 0.0 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Asp_protease_2 PF13650.1 OAJ09725.1 - 0.00085 19.7 0.0 0.0019 18.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ09725.1 - 0.0017 18.2 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ09725.1 - 0.026 14.3 0.1 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease rve PF00665.21 OAJ09726.1 - 1.1e-14 54.5 0.0 2.3e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ09726.1 - 8.2e-14 51.4 0.0 1.8e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 OAJ09726.1 - 9.3e-13 47.7 0.0 5.4e-11 41.9 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) KfrA_N PF11740.3 OAJ09726.1 - 1.1 9.6 9.5 0.86 10.0 0.6 2.8 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term HTH_28 PF13518.1 OAJ09731.1 - 0.0043 17.0 0.0 0.027 14.4 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 OAJ09731.1 - 0.066 12.8 0.2 0.38 10.4 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain RVT_1 PF00078.22 OAJ09739.1 - 4.4e-27 94.8 0.0 7.2e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 OAJ09744.1 - 1.4e-45 155.4 0.0 2.4e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ09744.1 - 1.8e-25 89.5 0.0 3.2e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ09744.1 - 0.00054 19.0 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Phage_GP20 PF06810.6 OAJ09744.1 - 0.0072 15.7 0.6 0.0072 15.7 0.4 2.2 2 0 0 2 2 2 1 Phage minor structural protein GP20 Filament PF00038.16 OAJ09744.1 - 0.0082 15.6 13.6 0.0082 15.6 9.4 2.2 1 1 0 2 2 2 1 Intermediate filament protein TcdB_N PF12918.2 OAJ09744.1 - 0.051 13.6 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain RIO1 PF01163.17 OAJ09744.1 - 0.08 12.2 0.1 0.08 12.2 0.1 2.2 2 0 0 2 2 2 0 RIO1 family Sec8_exocyst PF04048.9 OAJ09744.1 - 0.2 11.2 9.1 0.9 9.1 0.2 2.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Occludin_ELL PF07303.8 OAJ09744.1 - 0.21 12.3 6.8 1.9 9.2 0.0 2.5 2 0 0 2 2 2 0 Occludin homology domain TBPIP PF07106.8 OAJ09744.1 - 1.1 8.7 15.1 0.25 10.8 4.6 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2937 PF11157.3 OAJ09744.1 - 2.5 7.4 12.0 4.4 6.5 4.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) FlxA PF14282.1 OAJ09744.1 - 3.1 7.7 16.6 1.3 8.9 7.8 2.4 2 1 0 2 2 2 0 FlxA-like protein Viral_P18 PF04521.8 OAJ09744.1 - 3.6 7.0 13.1 3.8 6.9 0.2 3.1 2 1 1 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein PhoU PF01895.14 OAJ09744.1 - 5 7.6 9.2 3.9 8.0 1.0 2.9 2 1 1 3 3 3 0 PhoU domain zf-BED PF02892.10 OAJ09760.1 - 0.00045 19.9 2.1 0.00096 18.8 1.4 1.5 1 0 0 1 1 1 1 BED zinc finger Ecl1 PF12855.2 OAJ09773.1 - 4.3e-06 25.9 0.7 8.5e-06 24.9 0.5 1.5 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 OAJ09773.1 - 0.00038 20.2 1.5 0.001 18.8 1.0 1.7 1 0 0 1 1 1 1 MYND finger Dicty_REP PF05086.7 OAJ09773.1 - 1.8 6.1 5.3 3.3 5.3 3.7 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Innate_immun PF12782.2 OAJ09774.1 - 1.6 7.8 6.9 1.8 7.6 4.8 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family KOW PF00467.24 OAJ09778.1 - 0.042 13.5 0.3 0.078 12.7 0.2 1.4 1 0 0 1 1 1 0 KOW motif CTD PF12815.2 OAJ09778.1 - 0.079 13.3 15.3 0.25 11.7 2.0 2.4 1 1 1 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 UCH PF00443.24 OAJ09779.1 - 1.3e-80 270.4 0.0 2.5e-80 269.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ09779.1 - 9.4e-20 71.2 0.0 8.8e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 OAJ09779.1 - 3.8e-13 49.6 0.0 9.7e-13 48.3 0.0 1.8 1 0 0 1 1 1 1 DUSP domain USP7_C2 PF14533.1 OAJ09779.1 - 0.0059 16.0 0.0 3 7.2 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin-specific protease C-terminal zf-FPG_IleRS PF06827.9 OAJ09779.1 - 0.1 12.2 0.9 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS CW_binding_1 PF01473.15 OAJ09779.1 - 0.12 12.5 1.9 0.31 11.2 0.6 2.1 2 0 0 2 2 2 0 Putative cell wall binding repeat RVT_2 PF07727.9 OAJ09785.1 - 1.2e-72 243.8 0.0 1.7e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09785.1 - 4.1e-28 97.8 0.0 3e-27 95.1 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain rve_3 PF13683.1 OAJ09785.1 - 0.00028 20.3 0.0 0.001 18.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 OAJ09785.1 - 0.029 14.1 0.0 0.079 12.7 0.0 1.7 1 0 0 1 1 1 0 DDE superfamily endonuclease gag_pre-integrs PF13976.1 OAJ09786.1 - 0.00024 20.6 1.3 0.00059 19.4 0.0 2.4 2 0 0 2 2 2 1 GAG-pre-integrase domain Ndc1_Nup PF09531.5 OAJ09786.1 - 0.27 9.5 1.6 0.39 9.0 1.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DLIC PF05783.6 OAJ09786.1 - 1.5 7.3 4.3 2.9 6.4 0.1 2.1 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) DUF605 PF04652.11 OAJ09786.1 - 1.9 7.7 7.8 2.7 7.3 5.4 1.1 1 0 0 1 1 1 0 Vta1 like TAP42 PF04177.7 OAJ09793.1 - 0.054 12.4 0.2 0.065 12.1 0.1 1.1 1 0 0 1 1 1 0 TAP42-like family CPSF_A PF03178.10 OAJ09798.1 - 1.4e-43 149.2 0.0 2.1e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 OAJ09798.1 - 7.6e-17 60.6 0.0 1.2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CSTF2_hinge PF14327.1 OAJ09799.1 - 2.5e-27 94.7 6.5 6.3e-27 93.4 4.5 1.7 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 OAJ09799.1 - 1.7e-22 78.8 0.1 2.6e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ09799.1 - 9.5e-15 54.3 0.0 2.1e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 OAJ09799.1 - 1.9e-12 46.2 2.5 1.9e-12 46.2 1.7 2.8 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 OAJ09799.1 - 5.9e-07 29.2 0.0 1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 OAJ09805.1 - 1.1e-52 178.7 0.0 1.1e-52 178.7 0.0 3.2 4 1 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ09805.1 - 1.9e-21 76.3 0.0 1.9e-21 76.3 0.0 3.0 4 0 0 4 4 4 1 Protein tyrosine kinase Med15 PF09606.5 OAJ09806.1 - 0.023 12.9 18.6 0.029 12.6 12.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 OAJ09806.1 - 0.44 8.7 16.5 0.68 8.1 11.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 OAJ09806.1 - 1.6 6.3 16.3 2.2 5.9 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ctf8 PF09696.5 OAJ09812.1 - 1.1e-11 44.6 0.3 3e-11 43.1 0.2 1.6 1 1 0 1 1 1 1 Ctf8 zf-CCCH PF00642.19 OAJ09813.1 - 1.4e-18 66.0 14.9 6.3e-11 41.6 1.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 OAJ09813.1 - 10 6.3 11.0 0.79 9.8 0.3 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type p450 PF00067.17 OAJ09819.1 - 5.3e-59 199.9 0.0 1e-58 198.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 FTO_CTD PF12934.2 OAJ09819.1 - 0.049 13.2 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 FTO C-terminal domain PIF1 PF05970.9 OAJ09826.1 - 7.5e-15 54.7 0.0 8.8e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ09826.1 - 4.8e-05 23.0 0.0 5.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ09826.1 - 0.00075 19.1 0.2 0.00096 18.8 0.1 1.3 1 0 0 1 1 1 1 Part of AAA domain ArgK PF03308.11 OAJ09826.1 - 0.0051 15.6 0.1 0.0059 15.4 0.0 1.1 1 0 0 1 1 1 1 ArgK protein Helitron_like_N PF14214.1 OAJ09827.1 - 7.1e-33 113.8 0.0 1.2e-32 113.1 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Ima1_N PF09779.4 OAJ09833.1 - 2.4 8.6 5.5 8.1 6.9 0.2 2.7 2 0 0 2 2 2 0 Ima1 N-terminal domain CIA30 PF08547.7 OAJ09840.1 - 0.022 14.6 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) CAF-1_p150 PF11600.3 OAJ09840.1 - 4.5 6.5 4.8 5.6 6.2 3.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF508 PF04370.7 OAJ09840.1 - 6.8 6.2 7.1 9.7 5.8 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Tim44 PF04280.10 OAJ09841.1 - 2.5e-14 53.4 2.4 5.1e-12 46.0 0.0 3.0 3 0 0 3 3 3 2 Tim44-like domain Seipin PF06775.9 OAJ09846.1 - 2.7e-39 134.7 0.0 9.1e-26 90.6 0.0 2.2 2 0 0 2 2 2 2 Putative adipose-regulatory protein (Seipin) SDA1 PF05285.7 OAJ09846.1 - 1.1 8.5 31.6 0.51 9.5 9.8 2.4 2 0 0 2 2 2 0 SDA1 tRNA-synt_His PF13393.1 OAJ09847.1 - 2.8e-37 128.4 1.1 8.6e-33 113.7 0.0 3.0 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 OAJ09847.1 - 1.3e-18 67.1 0.0 2.2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ09847.1 - 2e-07 30.8 0.0 3.8e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.15 OAJ09847.1 - 2.4e-06 27.1 2.0 2.4e-06 27.1 1.4 2.2 2 0 0 2 2 2 1 WHEP-TRS domain tRNA-synt_2 PF00152.15 OAJ09847.1 - 9e-05 21.3 0.2 0.013 14.3 0.1 2.4 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) Proteasome PF00227.21 OAJ09853.1 - 9.7e-51 171.7 0.0 1.3e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAJ09853.1 - 1.2e-11 43.7 0.1 2e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Mito_carr PF00153.22 OAJ09854.1 - 4.5e-64 212.2 3.4 2.4e-21 75.2 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein MGS PF02142.17 OAJ09855.1 - 0.00061 19.6 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Epimerase PF01370.16 OAJ09855.1 - 0.097 12.0 0.0 0.21 11.0 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ApbE PF02424.10 OAJ09861.1 - 0.15 11.3 0.0 2.3 7.4 0.0 2.6 3 0 0 3 3 3 0 ApbE family RVT_1 PF00078.22 OAJ09866.1 - 1.2e-05 24.8 0.0 2.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ09866.1 - 2e-05 24.9 0.0 6.3e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ09866.1 - 3.5e-05 23.6 0.0 8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 OAJ09866.1 - 0.00019 21.0 0.0 0.00038 20.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Rad60-SLD PF11976.3 OAJ09866.1 - 0.0008 19.0 0.0 0.0029 17.2 0.0 2.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like gag-asp_proteas PF13975.1 OAJ09866.1 - 0.00093 18.9 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 OAJ09866.1 - 0.0071 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease CENP-F_leu_zip PF10473.4 OAJ09867.1 - 7.4e-05 22.6 1.5 0.00012 21.9 1.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YlbD_coat PF14071.1 OAJ09867.1 - 0.0073 16.3 0.3 0.1 12.6 0.0 2.1 2 0 0 2 2 2 1 Putative coat protein COG5 PF10392.4 OAJ09867.1 - 0.07 13.0 1.0 0.15 12.0 0.7 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF3732 PF12532.3 OAJ09867.1 - 3 7.3 6.5 3.6 7.0 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3732) UBN2 PF14223.1 OAJ09871.1 - 4.1e-05 23.3 0.0 7.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ09871.1 - 0.019 14.9 4.0 0.03 14.2 2.7 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.9 OAJ09872.1 - 4.6e-63 212.4 0.0 1.5e-56 191.0 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ09872.1 - 1.2e-28 99.6 0.0 3.2e-28 98.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ09872.1 - 3.2e-06 26.6 0.0 6.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ09872.1 - 5.8e-05 22.5 0.1 0.00021 20.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Amino_oxidase PF01593.19 OAJ09875.1 - 3.3e-37 128.6 0.0 5.9e-37 127.8 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAJ09875.1 - 6.6e-12 45.2 0.5 1.7e-11 43.9 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ09875.1 - 1.3e-06 27.6 1.5 9.8e-06 24.6 1.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 OAJ09875.1 - 1.8e-06 26.7 2.4 0.0032 16.0 0.7 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 OAJ09875.1 - 1.8e-05 23.8 0.8 2.7e-05 23.1 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 OAJ09875.1 - 0.00017 20.7 0.2 0.00028 20.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 OAJ09875.1 - 0.00078 19.5 0.6 0.3 11.1 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ09875.1 - 0.00082 19.7 0.6 0.003 17.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ09875.1 - 0.0014 17.8 0.6 0.0024 17.0 0.4 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 OAJ09875.1 - 0.0025 17.5 0.4 0.39 10.4 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 OAJ09875.1 - 0.0044 16.0 0.3 2.1 7.1 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 OAJ09875.1 - 0.007 16.2 0.4 0.021 14.7 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DNA_pol_B PF00136.16 OAJ09876.1 - 6.1e-149 496.7 2.1 9.1e-149 496.1 1.5 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 OAJ09876.1 - 8.3e-87 291.0 0.0 1.3e-86 290.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 OAJ09876.1 - 7.8e-22 77.0 6.7 1.7e-21 76.0 4.7 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 OAJ09876.1 - 0.0016 17.2 2.9 0.015 14.0 0.0 2.9 3 0 0 3 3 3 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.4 OAJ09876.1 - 0.0019 17.7 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 OAJ09876.1 - 0.0054 16.5 0.6 0.021 14.6 0.1 2.4 2 1 0 2 2 2 1 RNase_H superfamily zf-RING-like PF08746.6 OAJ09876.1 - 0.14 12.1 5.5 0.062 13.3 0.7 2.5 2 0 0 2 2 2 0 RING-like domain HTH_DeoR PF08220.7 OAJ09888.1 - 0.0071 15.8 0.0 0.018 14.5 0.1 1.7 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain DUF2884 PF11101.3 OAJ09888.1 - 0.032 13.6 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) CKS PF01111.14 OAJ09888.1 - 0.12 12.2 0.1 0.23 11.3 0.0 1.5 1 1 1 2 2 2 0 Cyclin-dependent kinase regulatory subunit DUF4413 PF14372.1 OAJ09889.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Nucleo_P87 PF07267.6 OAJ09889.1 - 4.9 5.7 10.3 8.3 4.9 7.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-MYND PF01753.13 OAJ09890.1 - 0.0069 16.2 2.5 0.013 15.3 1.7 1.4 1 0 0 1 1 1 1 MYND finger Pkinase PF00069.20 OAJ09891.1 - 3.2e-35 121.5 0.0 5.1e-27 94.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ09891.1 - 1.4e-16 60.3 0.0 4e-15 55.5 0.0 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ09891.1 - 1.1e-05 24.5 0.0 6.6e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RAP1 PF07218.6 OAJ09891.1 - 0.073 11.1 0.3 0.12 10.4 0.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) APH PF01636.18 OAJ09891.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 OAJ09891.1 - 0.17 10.9 0.0 0.44 9.5 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAG PF15347.1 OAJ09891.1 - 0.21 10.6 0.8 0.34 9.9 0.6 1.2 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Pox_ser-thr_kin PF05445.6 OAJ09891.1 - 0.23 10.2 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Dimer_Tnp_hAT PF05699.9 OAJ09892.1 - 1.3e-19 69.5 0.3 1.9e-19 69.0 0.2 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region dCMP_cyt_deam_1 PF00383.17 OAJ09898.1 - 7.8e-20 70.4 0.0 1.4e-19 69.6 0.0 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 OAJ09898.1 - 1.8e-06 27.8 0.0 2.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Bd3614-like deaminase RimK PF08443.6 OAJ09898.1 - 0.087 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain PNRC PF15365.1 OAJ09898.1 - 0.56 10.2 3.9 1.3 9.1 2.7 1.7 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator EMP24_GP25L PF01105.19 OAJ09899.1 - 2.5e-34 118.5 0.1 3.2e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GRAM PF02893.15 OAJ09900.1 - 1.5e-19 69.2 0.1 1.6e-18 66.0 0.0 2.3 2 0 0 2 2 2 1 GRAM domain DUF3262 PF11660.3 OAJ09900.1 - 0.3 11.1 1.6 0.72 9.9 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Mito_carr PF00153.22 OAJ09912.1 - 5.3e-06 26.0 2.0 0.012 15.3 0.0 2.8 2 1 0 2 2 2 2 Mitochondrial carrier protein Asn_synthase PF00733.16 OAJ09921.1 - 7e-15 55.2 0.0 9.2e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_6 PF13522.1 OAJ09921.1 - 0.005 16.7 0.0 0.063 13.2 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain NAD_synthase PF02540.12 OAJ09921.1 - 0.071 11.9 0.0 0.096 11.5 0.0 1.1 1 0 0 1 1 1 0 NAD synthase Pol_alpha_B_N PF08418.5 OAJ09922.1 - 0.56 9.6 6.0 0.98 8.8 4.1 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SOG2 PF10428.4 OAJ09922.1 - 3.9 6.0 11.2 5.7 5.4 7.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ribosomal_S15 PF00312.17 OAJ09928.1 - 2.5e-17 62.3 0.1 2.5e-17 62.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_L3 PF00297.17 OAJ09929.1 - 7.4e-31 107.5 1.9 3.7e-30 105.2 1.5 1.8 1 1 0 1 1 1 1 Ribosomal protein L3 Muskelin_N PF06588.6 OAJ09931.1 - 1.5e-41 142.2 0.1 9.9e-33 113.5 0.0 2.1 2 0 0 2 2 2 2 Muskelin N-terminus Kelch_6 PF13964.1 OAJ09931.1 - 8.4e-12 44.7 2.8 0.036 14.2 0.0 6.9 7 0 0 7 7 7 3 Kelch motif Kelch_3 PF13415.1 OAJ09931.1 - 1.1e-11 44.5 24.3 1e-05 25.5 0.6 8.7 8 2 0 8 8 8 4 Galactose oxidase, central domain Kelch_5 PF13854.1 OAJ09931.1 - 4.8e-11 42.3 5.8 0.003 17.4 0.0 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 OAJ09931.1 - 3e-10 39.4 0.2 0.00028 20.3 0.1 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 OAJ09931.1 - 4.1e-05 23.2 19.4 0.0012 18.5 0.1 7.1 7 1 0 7 7 7 2 Galactose oxidase, central domain Kelch_2 PF07646.10 OAJ09931.1 - 0.00039 20.0 5.7 0.07 12.9 0.1 4.8 5 0 0 5 5 5 2 Kelch motif tRNA_int_endo PF01974.12 OAJ09932.1 - 4.9e-15 55.1 0.0 7.8e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Polysacc_deac_1 PF01522.16 OAJ09933.1 - 0.0011 18.5 0.1 0.0035 16.9 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide deacetylase rve PF00665.21 OAJ09937.1 - 3.2e-14 53.0 0.0 9e-14 51.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ09937.1 - 7.3e-12 45.0 0.1 1.6e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 OAJ09937.1 - 1.4e-06 28.0 0.0 4.8e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 OAJ09937.1 - 5.9e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.19 OAJ09937.1 - 9.7e-05 21.9 1.2 0.00025 20.6 0.3 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 OAJ09937.1 - 0.00023 21.5 0.0 0.00052 20.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 OAJ09937.1 - 0.00091 19.0 2.4 0.0017 18.1 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 OAJ09937.1 - 0.007 16.0 0.5 0.025 14.2 0.3 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ09937.1 - 0.016 14.9 0.1 0.045 13.4 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle PHY PF00360.15 OAJ09939.1 - 1.1e-24 86.5 0.0 2.4e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 OAJ09939.1 - 9e-19 67.2 0.1 2e-18 66.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.21 OAJ09939.1 - 6.9e-13 49.0 0.0 2e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 GAF domain HisKA PF00512.20 OAJ09939.1 - 9.4e-13 47.9 0.7 2.4e-12 46.6 0.5 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 OAJ09939.1 - 6.4e-11 42.6 0.0 1.6e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold TRP PF06011.7 OAJ09939.1 - 9 4.7 4.3 15 4.0 3.0 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Response_reg PF00072.19 OAJ09940.1 - 1e-15 57.6 0.1 1.1e-14 54.3 0.1 2.0 1 1 0 1 1 1 1 Response regulator receiver domain DUF4177 PF13783.1 OAJ09940.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) Myb_DNA-bind_3 PF12776.2 OAJ09945.1 - 4.4e-13 49.6 0.5 7.7e-13 48.9 0.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ09945.1 - 3.8e-05 23.7 1.4 0.00042 20.3 1.0 2.2 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.1 OAJ09946.1 - 7e-23 80.9 0.0 9.3e-23 80.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ09946.1 - 1.7e-05 24.3 0.0 0.00025 20.4 0.0 2.0 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.16 OAJ09946.1 - 0.00064 19.3 0.0 0.018 14.6 0.0 2.1 1 1 0 1 1 1 1 Transposase DDE domain Pkinase PF00069.20 OAJ09952.1 - 9e-50 169.2 0.0 1.4e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ09952.1 - 1.8e-23 82.9 0.0 3.3e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 OAJ09952.1 - 0.0096 14.7 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Myc_N PF01056.13 OAJ09952.1 - 0.011 14.9 1.8 0.017 14.2 1.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Kinase-like PF14531.1 OAJ09952.1 - 0.13 11.1 0.1 0.78 8.6 0.0 2.2 2 1 0 2 2 2 0 Kinase-like Nucleoplasmin PF03066.10 OAJ09952.1 - 2.6 7.5 8.7 5.1 6.6 6.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin YuzL PF14115.1 OAJ09953.1 - 0.73 10.1 3.0 2.1 8.6 2.1 1.8 1 0 0 1 1 1 0 YuzL-like protein CPSase_L_chain PF00289.17 OAJ09955.1 - 0.00088 19.3 0.0 0.0011 19.0 0.0 1.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D2 PF02786.12 OAJ09956.1 - 1e-64 217.7 0.0 1.1e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 OAJ09956.1 - 1.1e-15 57.9 0.0 1.2e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 OAJ09956.1 - 3.1e-08 33.1 0.0 3.6e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAJ09956.1 - 2.9e-06 26.2 0.0 0.034 12.8 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 OAJ09956.1 - 2.9e-05 23.9 0.0 3.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 OAJ09956.1 - 8.7e-05 21.9 0.0 0.00026 20.4 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.1 OAJ09956.1 - 0.0059 15.8 0.1 0.0097 15.1 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 OAJ09956.1 - 0.13 11.7 0.0 0.56 9.6 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain CPSase_L_chain PF00289.17 OAJ09957.1 - 9.1e-17 61.1 0.0 1.3e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Pterin_bind PF00809.17 OAJ09982.1 - 5.3e-50 169.7 0.0 1.5e-49 168.2 0.0 1.8 1 1 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 OAJ09982.1 - 1.3e-27 96.0 0.1 3.3e-24 85.0 0.0 2.5 1 1 0 2 2 2 2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 OAJ09982.1 - 1.9e-21 76.3 0.0 3.9e-12 46.3 0.0 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase Rap1_C PF11626.3 OAJ09982.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DDE_1 PF03184.14 OAJ09983.1 - 1.5e-26 92.9 0.0 3.1e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease MIP-T3 PF10243.4 OAJ09983.1 - 0.4 9.0 36.1 0.61 8.4 25.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SRP-alpha_N PF04086.8 OAJ09983.1 - 1.4 8.1 24.3 2.1 7.6 16.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Borrelia_P83 PF05262.6 OAJ09983.1 - 2 6.5 32.6 3 6.0 22.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CAF-1_p150 PF11600.3 OAJ09983.1 - 2.6 7.3 56.1 4.1 6.7 38.9 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PLRV_ORF5 PF01690.12 OAJ09983.1 - 2.9 6.9 16.5 4.3 6.3 11.5 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DNA_pol_viral_N PF00242.12 OAJ09983.1 - 5.9 5.8 12.0 8.7 5.2 8.3 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Myc_N PF01056.13 OAJ09988.1 - 0.011 14.9 1.2 0.011 14.9 0.8 2.0 2 0 0 2 2 2 0 Myc amino-terminal region DUF4350 PF14258.1 OAJ09988.1 - 0.018 15.2 0.3 0.12 12.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Nucleoplasmin PF03066.10 OAJ09988.1 - 0.05 13.1 2.3 0.093 12.2 1.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF3953 PF13129.1 OAJ09988.1 - 0.95 9.1 3.3 0.32 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) CENP-B_dimeris PF09026.5 OAJ09988.1 - 3.4 7.9 9.3 7.7 6.8 6.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Brevenin PF03032.10 OAJ09988.1 - 3.8 7.4 4.9 7.5 6.4 3.4 1.5 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family PPTA PF01239.17 OAJ09989.1 - 1.6e-39 131.5 3.8 1.3e-09 36.9 0.2 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.1 OAJ09989.1 - 0.013 15.6 0.5 13 6.3 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ09989.1 - 0.04 14.5 1.5 2 9.3 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ09989.1 - 0.065 12.8 2.4 1.7 8.3 0.1 3.0 3 0 0 3 3 3 0 TPR repeat Serglycin PF04360.7 OAJ09989.1 - 0.11 12.2 0.3 4.7 6.9 0.3 2.2 2 0 0 2 2 2 0 Serglycin TPR_16 PF13432.1 OAJ09989.1 - 5.9 7.6 8.5 0.48 11.1 0.4 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat RPEL PF02755.10 OAJ09990.1 - 9.8e-19 66.0 8.2 8.2e-08 31.3 1.0 3.5 3 0 0 3 3 3 3 RPEL repeat MEA1 PF06910.6 OAJ09990.1 - 0.041 13.5 0.1 0.051 13.2 0.1 1.4 1 1 0 1 1 1 0 Male enhanced antigen 1 (MEA1) DUF1992 PF09350.5 OAJ09990.1 - 0.07 12.9 4.4 0.48 10.2 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1992) PilP PF04351.8 OAJ09990.1 - 0.71 9.7 5.7 2.9 7.7 1.4 2.6 1 1 2 3 3 3 0 Pilus assembly protein, PilP WW PF00397.21 OAJ09991.1 - 0.01 15.6 1.0 0.027 14.3 0.7 1.7 1 0 0 1 1 1 0 WW domain RNA_polI_A34 PF08208.6 OAJ09991.1 - 0.019 14.6 7.1 0.028 14.0 4.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 IncA PF04156.9 OAJ09991.1 - 0.036 13.6 0.8 0.052 13.1 0.6 1.1 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 OAJ09991.1 - 0.083 11.8 5.0 0.11 11.4 3.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ycf1 PF05758.7 OAJ09991.1 - 0.5 8.0 7.9 0.61 7.7 5.5 1.0 1 0 0 1 1 1 0 Ycf1 ATP-synt_E PF05680.7 OAJ09991.1 - 1.1 9.2 6.3 1.7 8.6 4.4 1.2 1 0 0 1 1 1 0 ATP synthase E chain Hid1 PF12722.2 OAJ09991.1 - 1.2 6.7 7.7 1.5 6.3 5.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 OAJ09991.1 - 1.3 7.9 5.1 1.9 7.4 3.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 OAJ09991.1 - 2.4 7.8 7.1 3.5 7.3 4.9 1.3 1 0 0 1 1 1 0 DDHD domain MIP-T3 PF10243.4 OAJ09991.1 - 3 6.2 24.9 4.2 5.7 17.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF572 PF04502.8 OAJ09991.1 - 3.2 6.8 20.7 4.6 6.3 14.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RVT_1 PF00078.22 OAJ09994.1 - 2.3e-07 30.3 0.0 4.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BASP1 PF05466.7 OAJ09994.1 - 0.25 11.1 3.1 0.55 10.0 2.2 1.5 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) rve PF00665.21 OAJ09995.1 - 8.4e-20 71.0 0.0 1.7e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ09995.1 - 0.014 14.8 0.0 0.05 13.1 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain Vps5 PF09325.5 OAJ10002.1 - 3.6e-09 36.2 4.3 0.00074 18.8 0.5 2.1 2 0 0 2 2 2 2 Vps5 C terminal like FAM92 PF06730.6 OAJ10002.1 - 0.011 15.0 0.7 0.022 14.1 0.5 1.4 1 0 0 1 1 1 0 FAM92 protein BAR_3_WASP_bdg PF10456.4 OAJ10002.1 - 0.059 12.6 0.6 0.41 9.8 0.1 2.0 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein BAR PF03114.13 OAJ10002.1 - 0.083 12.3 1.9 0.46 9.9 0.1 2.1 2 0 0 2 2 2 0 BAR domain Pkr1 PF08636.5 OAJ10008.1 - 0.77 9.8 7.7 0.18 11.8 2.3 2.1 1 1 1 2 2 2 0 ER protein Pkr1 bZIP_1 PF00170.16 OAJ10009.1 - 5.1e-06 26.3 7.7 5.1e-06 26.3 5.3 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 OAJ10009.1 - 0.0023 17.7 7.1 0.0023 17.7 4.9 2.4 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 OAJ10009.1 - 0.025 14.8 4.3 0.025 14.8 3.0 3.4 3 0 0 3 3 3 0 bZIP Maf transcription factor adh_short PF00106.20 OAJ10010.1 - 4.4e-15 56.0 1.3 8.2e-15 55.1 0.9 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ10010.1 - 4.3e-06 26.5 0.1 9.8e-06 25.3 0.1 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ10010.1 - 2e-05 24.4 0.0 7.4e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAJ10010.1 - 0.00021 21.3 0.3 0.0011 19.0 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 OAJ10010.1 - 0.0089 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 OAJ10010.1 - 0.013 14.9 0.0 2.4 7.5 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 OAJ10010.1 - 0.021 14.9 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 OAJ10010.1 - 0.11 12.3 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.8 OAJ10010.1 - 0.13 11.4 0.1 0.68 9.1 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family WD40 PF00400.27 OAJ10011.1 - 3.3e-49 163.0 12.9 1.4e-09 37.4 0.1 9.4 10 0 0 10 10 10 8 WD domain, G-beta repeat Nup160 PF11715.3 OAJ10011.1 - 0.00013 20.2 0.6 0.0095 14.1 0.0 3.1 2 2 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAJ10011.1 - 0.0008 18.2 0.0 0.4 9.3 0.0 3.4 3 0 0 3 3 3 1 Nup133 N terminal like Nbas_N PF15492.1 OAJ10011.1 - 0.011 14.8 0.1 2.3 7.2 0.0 3.1 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF3312 PF11768.3 OAJ10011.1 - 0.016 13.5 0.0 0.028 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF4394 PF14339.1 OAJ10011.1 - 0.027 13.7 1.2 0.17 11.1 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4394) PQQ PF01011.16 OAJ10011.1 - 0.031 13.8 2.7 14 5.4 0.1 4.2 4 0 0 4 4 4 0 PQQ enzyme repeat PQQ_3 PF13570.1 OAJ10011.1 - 3.7 7.9 22.1 4.9 7.5 0.1 6.7 5 2 1 6 6 6 0 PQQ-like domain Peptidase_M43 PF05572.8 OAJ10016.1 - 2.4e-13 49.9 0.0 4e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 OAJ10016.1 - 2.6e-05 24.7 0.0 4.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 OAJ10016.1 - 0.00081 18.9 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAJ10016.1 - 0.00092 19.1 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 OAJ10016.1 - 0.014 15.4 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 OAJ10016.1 - 0.035 12.9 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.19 OAJ10016.1 - 0.053 13.2 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Matrixin Peptidase_M43 PF05572.8 OAJ10017.1 - 2.8e-13 49.7 0.0 5.3e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 OAJ10017.1 - 3.5e-06 27.5 0.0 6.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 OAJ10017.1 - 0.00032 20.8 0.3 0.00055 20.0 0.1 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAJ10017.1 - 0.00055 19.9 0.1 0.0011 18.9 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 OAJ10017.1 - 0.009 15.5 0.3 0.025 14.1 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 OAJ10017.1 - 0.017 14.8 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Matrixin Peptidase_M54 PF07998.6 OAJ10017.1 - 0.16 11.6 0.1 0.59 9.8 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M54 Ytp1 PF10355.4 OAJ10018.1 - 2.2e-87 292.7 2.1 2.9e-87 292.3 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 OAJ10018.1 - 1.6e-17 62.9 0.4 1.6e-17 62.9 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) RNase_H PF00075.19 OAJ10023.1 - 0.00018 21.8 0.0 0.00041 20.6 0.0 1.5 1 0 0 1 1 1 1 RNase H DNA_pol_viral_N PF00242.12 OAJ10023.1 - 0.0049 15.9 17.3 0.11 11.5 6.2 2.2 2 0 0 2 2 2 2 DNA polymerase (viral) N-terminal domain RVT_3 PF13456.1 OAJ10023.1 - 0.046 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like RAP1 PF07218.6 OAJ10023.1 - 1.1 7.2 7.6 1.7 6.6 5.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Phage_integrase PF00589.17 OAJ10024.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Gemin6 PF06372.7 OAJ10024.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Gemin6 protein FAD_binding_3 PF01494.14 OAJ10029.1 - 7e-57 193.0 0.0 9.4e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain MHCassoc_trimer PF08831.5 OAJ10029.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain Redoxin PF08534.5 OAJ10029.1 - 0.15 11.6 0.0 24 4.4 0.0 2.8 2 1 1 3 3 3 0 Redoxin Abhydrolase_6 PF12697.2 OAJ10030.1 - 1.3e-34 120.0 0.1 1.9e-34 119.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ10030.1 - 7.6e-18 64.9 0.0 2e-16 60.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ10030.1 - 8.9e-14 51.4 0.0 5.5e-13 48.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAJ10030.1 - 0.006 16.0 0.0 0.14 11.5 0.0 2.2 2 0 0 2 2 2 1 Putative esterase Ndr PF03096.9 OAJ10030.1 - 0.009 14.5 0.0 0.02 13.3 0.0 1.6 1 1 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 OAJ10030.1 - 0.01 15.6 0.0 0.03 14.1 0.0 1.8 2 0 0 2 2 2 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 OAJ10030.1 - 0.025 14.1 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 OAJ10030.1 - 0.055 13.0 0.0 0.29 10.6 0.0 1.9 1 1 0 1 1 1 0 PGAP1-like protein Amidohydro_1 PF01979.15 OAJ10031.1 - 4.5e-15 56.1 0.0 5.7e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 OAJ10031.1 - 5.8e-08 33.1 0.4 8.8e-08 32.5 0.3 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 OAJ10031.1 - 7.5e-07 28.7 0.1 8.9e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family MFS_1 PF07690.11 OAJ10032.1 - 2.2e-12 46.3 29.4 2.2e-12 46.3 20.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Polysacc_deac_1 PF01522.16 OAJ10036.1 - 1.5e-24 86.0 0.0 2.8e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 OAJ10036.1 - 0.014 14.3 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 PSK_trans_fac PF07704.6 OAJ10037.1 - 0.0095 16.5 1.1 0.016 15.9 0.8 1.3 1 0 0 1 1 1 1 Rv0623-like transcription factor zf-CCHC PF00098.18 OAJ10038.1 - 0.00064 19.5 5.2 0.0014 18.4 3.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ10038.1 - 0.037 13.7 0.4 0.085 12.6 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Frag1 PF10277.4 OAJ10044.1 - 1.8e-17 63.5 5.9 2.1e-17 63.3 4.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Cation_efflux PF01545.16 OAJ10044.1 - 0.0013 17.9 2.7 0.0015 17.6 1.8 1.0 1 0 0 1 1 1 1 Cation efflux family Yip1 PF04893.12 OAJ10044.1 - 0.0023 17.4 0.7 0.0027 17.2 0.5 1.1 1 0 0 1 1 1 1 Yip1 domain DUF1345 PF07077.6 OAJ10044.1 - 0.0079 15.7 0.2 0.0096 15.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1345) PIG-U PF06728.8 OAJ10044.1 - 0.075 11.8 3.2 0.31 9.8 2.2 1.8 1 1 0 1 1 1 0 GPI transamidase subunit PIG-U PalH PF08733.5 OAJ10044.1 - 0.45 9.2 3.3 0.58 8.9 2.3 1.1 1 0 0 1 1 1 0 PalH/RIM21 RWD PF05773.17 OAJ10045.1 - 4.8e-19 68.3 0.2 7.6e-19 67.6 0.1 1.3 1 0 0 1 1 1 1 RWD domain TFIIA PF03153.8 OAJ10045.1 - 0.054 13.3 3.6 0.06 13.2 2.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3410 PF11890.3 OAJ10045.1 - 0.24 11.0 2.6 15 5.3 0.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3410) OmpH PF03938.9 OAJ10045.1 - 4.6 7.1 12.1 0.68 9.8 1.5 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Peroxidase_2 PF01328.12 OAJ10047.1 - 0.0038 15.9 0.3 0.0055 15.4 0.2 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 MSP1b PF03429.8 OAJ10047.1 - 0.19 9.5 0.0 0.27 9.0 0.0 1.1 1 0 0 1 1 1 0 Major surface protein 1B UBN2_2 PF14227.1 OAJ10052.1 - 2.5e-05 23.8 0.1 3.2e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type VP4_haemagglut PF00426.13 OAJ10052.1 - 0.018 13.0 0.0 0.023 12.7 0.0 1.0 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) UBN2 PF14223.1 OAJ10052.1 - 0.051 13.3 0.2 0.069 12.9 0.1 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DDE_1 PF03184.14 OAJ10061.1 - 1.5e-32 112.5 0.0 2.3e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAJ10061.1 - 1.4e-10 40.8 0.1 7.2e-10 38.5 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain TMEM191C PF15194.1 OAJ10061.1 - 0.79 9.6 3.4 0.56 10.0 0.5 2.2 2 0 0 2 2 2 0 TMEM191C family CcdA PF07362.7 OAJ10062.1 - 0.022 14.6 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA YlqD PF11068.3 OAJ10062.1 - 0.065 13.2 1.0 0.081 12.9 0.7 1.1 1 0 0 1 1 1 0 YlqD protein AATF-Che1 PF13339.1 OAJ10062.1 - 0.47 10.6 3.8 7.4 6.7 0.4 2.3 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Ammonium_transp PF00909.16 OAJ10070.1 - 1.1e-26 93.2 0.6 2.4e-15 55.9 0.0 2.1 1 1 1 2 2 2 2 Ammonium Transporter Family Malate_synthase PF01274.17 OAJ10070.1 - 3.8e-11 41.6 0.0 4.8e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 Malate synthase YqzM PF14141.1 OAJ10070.1 - 0.0045 16.7 0.1 0.0084 15.8 0.1 1.4 1 0 0 1 1 1 1 YqzM-like protein RNA_pol_I_A49 PF06870.7 OAJ10071.1 - 1.3e-07 30.5 0.0 1.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Thymidylat_synt PF00303.14 OAJ10076.1 - 2.3e-105 351.4 0.0 3.5e-105 350.8 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.17 OAJ10076.1 - 3.1e-29 102.0 0.1 9.3e-29 100.5 0.1 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Methyltransf_23 PF13489.1 OAJ10077.1 - 0.032 13.9 0.0 0.045 13.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ10077.1 - 0.089 13.3 0.6 1.7 9.2 0.2 2.7 2 1 0 2 2 2 0 Methyltransferase domain TehB PF03848.9 OAJ10077.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_25 PF13649.1 OAJ10077.1 - 0.12 12.6 0.1 0.33 11.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Cid2 PF09774.4 OAJ10078.1 - 0.05 13.7 0.4 0.064 13.3 0.3 1.3 1 1 0 1 1 1 0 Caffeine-induced death protein 2 SPC25 PF06703.6 OAJ10084.1 - 7.1e-35 119.9 0.0 9.3e-35 119.6 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Aminotran_5 PF00266.14 OAJ10085.1 - 2.4e-29 102.2 0.0 3.7e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 OAJ10085.1 - 0.00047 20.0 0.0 0.00091 19.0 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain GILT PF03227.11 OAJ10086.1 - 3.4e-08 33.2 0.1 6.8e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Pkinase PF00069.20 OAJ10094.1 - 9.1e-47 159.3 0.0 2.1e-32 112.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ10094.1 - 1.9e-19 69.7 0.0 1.7e-18 66.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ10094.1 - 2e-05 23.7 0.0 4.6e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAJ10094.1 - 4.2e-05 23.3 0.0 9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ10094.1 - 0.0055 15.7 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_3 PF00933.16 OAJ10098.1 - 1.7e-50 171.7 1.4 3.2e-50 170.8 0.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 OAJ10098.1 - 0.092 12.2 0.1 0.092 12.2 0.1 2.7 3 0 0 3 3 3 0 Glycosyl hydrolase family 3 C-terminal domain TLD PF07534.11 OAJ10099.1 - 1.4e-24 86.6 0.0 4.7e-21 75.2 0.0 3.1 2 1 0 2 2 2 2 TLD Cyt-b5 PF00173.23 OAJ10106.1 - 3.3e-09 36.3 0.0 4.8e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TAP35_44 PF07265.6 OAJ10106.1 - 0.063 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 DEAD PF00270.24 OAJ10107.1 - 6.3e-09 35.5 0.0 9.4e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 OAJ10107.1 - 0.12 11.6 0.0 0.37 10.0 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein HECT PF00632.20 OAJ10108.1 - 6.1e-91 304.8 0.0 9.7e-91 304.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBN2 PF14223.1 OAJ10113.1 - 4.6e-10 39.3 0.6 8.5e-10 38.4 0.4 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ10113.1 - 8.3e-05 22.3 2.7 8.3e-05 22.3 1.9 1.6 2 0 0 2 2 2 1 Zinc knuckle UBN2_2 PF14227.1 OAJ10113.1 - 0.003 17.0 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Peptidase_M24 PF00557.19 OAJ10114.1 - 1.4e-41 142.3 0.1 1.9e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 CDC45 PF02724.9 OAJ10114.1 - 0.058 11.4 4.5 0.08 10.9 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.6 OAJ10114.1 - 0.18 10.7 6.5 0.37 9.7 4.5 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) BAF1_ABF1 PF04684.8 OAJ10114.1 - 1.5 7.5 8.0 2.3 6.9 5.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Nop14 PF04147.7 OAJ10114.1 - 3.8 5.3 8.3 6.2 4.5 5.8 1.2 1 0 0 1 1 1 0 Nop14-like family Cnd2 PF05786.9 OAJ10114.1 - 5 5.5 8.9 7.2 4.9 6.2 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 RVT_2 PF07727.9 OAJ10116.1 - 9e-81 270.4 0.0 1.1e-80 270.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAJ10116.1 - 0.0066 15.8 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2360 PF10152.4 OAJ10116.1 - 4 7.7 6.5 7 6.9 4.5 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Barstar PF01337.13 OAJ10132.1 - 0.014 15.2 2.8 0.047 13.5 0.0 3.1 3 2 2 5 5 5 0 Barstar (barnase inhibitor) DUF4574 PF15141.1 OAJ10132.1 - 0.15 11.7 6.0 0.27 10.9 3.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4574) Phage_Gp23 PF10669.4 OAJ10132.1 - 3.6 7.7 19.3 2.7 8.1 2.9 2.6 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) ADIP PF11559.3 OAJ10132.1 - 7.6 6.4 32.9 0.44 10.4 5.6 2.7 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Transposase_21 PF02992.9 OAJ10133.1 - 6.2e-21 74.5 0.0 9.4e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ10133.1 - 0.00051 19.4 0.0 0.00089 18.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) ATP_bind_4 PF01902.12 OAJ10147.1 - 1.9e-40 138.5 0.0 5.6e-29 101.0 0.0 2.3 2 0 0 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 OAJ10147.1 - 1.9e-22 79.2 0.1 2.3e-15 56.4 0.1 2.5 2 0 0 2 2 2 2 Endoribonuclease L-PSP tRNA_Me_trans PF03054.11 OAJ10147.1 - 0.0086 14.6 0.0 0.013 14.1 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase VEFS-Box PF09733.4 OAJ10147.1 - 0.067 12.8 0.2 0.57 9.8 0.0 2.3 2 0 0 2 2 2 0 VEFS-Box of polycomb protein NMD3 PF04981.8 OAJ10148.1 - 5.3e-76 254.8 0.5 7.8e-76 254.2 0.4 1.3 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 OAJ10148.1 - 0.011 15.5 6.5 0.047 13.5 3.1 2.6 2 1 1 3 3 3 0 Double zinc ribbon Ribosomal_L37e PF01907.14 OAJ10148.1 - 1.4 8.8 3.5 17 5.2 0.1 2.7 2 0 0 2 2 2 0 Ribosomal protein L37e zf-dskA_traR PF01258.12 OAJ10148.1 - 6.8 6.5 6.6 0.68 9.7 0.0 2.6 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger THUMP PF02926.12 OAJ10153.1 - 8.3e-14 51.6 0.1 2.2e-13 50.3 0.0 1.7 2 0 0 2 2 2 1 THUMP domain Pkinase PF00069.20 OAJ10154.1 - 5e-64 215.9 0.0 6.4e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ10154.1 - 2.5e-44 151.3 0.0 3.3e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ10154.1 - 7.7e-09 34.9 0.0 1.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ10154.1 - 7.2e-06 25.9 0.3 0.0083 15.8 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 OAJ10154.1 - 0.071 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YadA_anchor PF03895.10 OAJ10158.1 - 0.84 9.6 13.1 0.33 10.9 1.9 3.7 3 0 0 3 3 3 0 YadA-like C-terminal region ParA PF10609.4 OAJ10160.1 - 9.2e-26 89.5 0.0 1.6e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 OAJ10160.1 - 1.2e-14 54.2 0.2 1e-13 51.1 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 OAJ10160.1 - 9e-07 28.9 0.1 2.4e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ10160.1 - 0.00039 20.1 1.6 0.46 10.2 0.1 2.6 3 0 0 3 3 3 2 Part of AAA domain AAA_25 PF13481.1 OAJ10160.1 - 0.00099 18.5 0.0 0.003 16.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 OAJ10160.1 - 0.0023 17.0 0.0 0.016 14.2 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_26 PF13500.1 OAJ10160.1 - 0.0059 16.2 0.1 0.49 9.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 OAJ10160.1 - 0.053 12.5 0.7 0.26 10.2 0.1 2.2 2 1 1 3 3 3 0 Anion-transporting ATPase Fer4_NifH PF00142.13 OAJ10160.1 - 0.064 12.4 0.1 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SDA1 PF05285.7 OAJ10166.1 - 1.1e-70 238.5 56.1 1.7e-34 119.6 12.7 3.8 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.7 OAJ10166.1 - 3.6e-15 55.9 0.1 6.7e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 NUC130/3NT domain DEAD PF00270.24 OAJ10167.1 - 8.9e-33 113.1 0.0 4.1e-31 107.7 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ10167.1 - 1.1e-17 63.6 0.0 2.4e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ10167.1 - 1.2e-05 25.2 0.0 4.8e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 OAJ10167.1 - 0.014 15.5 0.1 1.3 9.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain Nucleoplasmin PF03066.10 OAJ10167.1 - 0.29 10.6 11.3 4.3 6.8 4.0 2.6 2 0 0 2 2 2 0 Nucleoplasmin UQ_con PF00179.21 OAJ10168.1 - 1.6e-41 141.0 0.0 2.1e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 OAJ10168.1 - 0.0049 16.7 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 OAJ10168.1 - 0.033 13.9 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Saccharop_dh PF03435.13 OAJ10174.1 - 7.4e-12 44.9 0.5 1.4e-11 44.0 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase Phage_connect_1 PF05135.8 OAJ10187.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein RVT_2 PF07727.9 OAJ10189.1 - 1.5e-60 204.2 0.0 1.7e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Toxin_22 PF08092.6 OAJ10189.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Magi peptide toxin family rve PF00665.21 OAJ10190.1 - 3.8e-17 62.5 0.0 6.7e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ10190.1 - 4.3e-07 29.4 0.5 1.5e-06 27.7 0.2 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain SnoaL_2 PF12680.2 OAJ10194.1 - 0.074 13.4 0.0 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 SnoaL-like domain LtrA PF06772.6 OAJ10195.1 - 5.8e-17 61.6 22.1 4.4e-09 35.7 0.3 2.4 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) LAT PF15234.1 OAJ10200.1 - 0.068 12.6 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells DUF4017 PF13209.1 OAJ10200.1 - 0.1 12.4 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) ABC_membrane PF00664.18 OAJ10201.1 - 6.9e-96 320.8 25.0 1.2e-50 172.4 9.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ10201.1 - 1.6e-68 229.2 0.0 2.7e-33 115.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAJ10201.1 - 8.5e-17 61.1 1.3 9.8e-05 21.6 0.0 4.4 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAJ10201.1 - 5.5e-14 52.8 0.0 0.021 14.7 0.0 4.3 3 1 0 4 4 4 4 AAA domain ABC_ATPase PF09818.4 OAJ10201.1 - 6.2e-14 51.4 1.7 0.00027 19.6 0.1 4.2 4 0 0 4 4 4 3 Predicted ATPase of the ABC class AAA_29 PF13555.1 OAJ10201.1 - 1.6e-08 33.9 1.0 0.00033 20.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 OAJ10201.1 - 3.8e-07 30.9 0.0 0.036 14.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAJ10201.1 - 1.2e-06 28.6 0.4 0.16 12.1 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAJ10201.1 - 1.9e-06 27.9 6.7 0.011 15.6 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain DUF258 PF03193.11 OAJ10201.1 - 2.2e-06 26.9 0.0 0.071 12.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 OAJ10201.1 - 5.6e-06 25.8 0.1 0.051 12.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 OAJ10201.1 - 1.1e-05 25.2 2.0 0.13 12.1 0.2 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 OAJ10201.1 - 1.4e-05 25.5 0.3 0.32 11.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.1 OAJ10201.1 - 6e-05 22.7 0.3 0.36 10.3 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 OAJ10201.1 - 0.00022 21.5 0.0 0.69 10.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 OAJ10201.1 - 0.00035 20.4 0.0 2.3 8.1 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_5 PF07728.9 OAJ10201.1 - 0.00067 19.3 0.1 2.9 7.6 0.0 3.9 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) DUF87 PF01935.12 OAJ10201.1 - 0.001 18.9 0.2 2 8.1 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_33 PF13671.1 OAJ10201.1 - 0.0027 17.6 0.3 1.1 9.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain PRK PF00485.13 OAJ10201.1 - 0.0086 15.6 0.0 1.5 8.3 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 OAJ10201.1 - 0.01 15.8 0.5 4.7 7.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.1 OAJ10201.1 - 0.013 14.5 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 OAJ10201.1 - 0.022 14.2 0.5 2.3 7.6 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 OAJ10201.1 - 0.023 14.1 0.7 6.8 6.0 0.0 3.3 4 0 0 4 4 4 0 AAA-like domain Miro PF08477.8 OAJ10201.1 - 0.024 15.1 0.0 5.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 OAJ10201.1 - 0.024 14.7 0.0 6.1 7.0 0.0 3.3 3 0 0 3 3 2 0 RNA helicase Viral_helicase1 PF01443.13 OAJ10201.1 - 0.035 13.6 0.0 2.1 7.8 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.15 OAJ10201.1 - 0.036 13.7 0.1 0.76 9.4 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF815 PF05673.8 OAJ10201.1 - 0.04 12.8 0.0 7.9 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MobB PF03205.9 OAJ10201.1 - 0.045 13.4 0.1 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 OAJ10201.1 - 0.087 11.6 0.1 12 4.6 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.10 OAJ10201.1 - 0.13 10.9 0.0 1.2 7.7 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein MIP-T3 PF10243.4 OAJ10207.1 - 0.16 10.4 12.1 0.26 9.7 8.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NatB_MDM20 PF09797.4 OAJ10212.1 - 3.4e-49 167.5 0.0 5.3e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit DnaJ PF00226.26 OAJ10213.1 - 1e-24 85.9 0.8 1.3e-24 85.7 0.5 1.1 1 0 0 1 1 1 1 DnaJ domain RRM_3 PF08777.6 OAJ10213.1 - 0.054 13.3 0.0 0.066 13.0 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif COesterase PF00135.23 OAJ10214.1 - 6.7e-110 368.3 0.2 8.8e-110 367.9 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family CTDII PF01556.13 OAJ10214.1 - 6.6e-21 74.0 0.0 2.1e-15 56.3 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 OAJ10214.1 - 8.9e-14 51.2 18.6 1.5e-13 50.5 12.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Abhydrolase_3 PF07859.8 OAJ10214.1 - 7.8e-07 28.8 0.2 9.3e-06 25.3 0.0 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Cytochrom_c3_2 PF14537.1 OAJ10214.1 - 0.038 14.3 4.7 0.072 13.4 3.2 1.5 1 0 0 1 1 1 0 Cytochrome c3 Stc1 PF12898.2 OAJ10214.1 - 0.15 12.1 6.9 0.73 9.9 1.1 2.4 2 0 0 2 2 2 0 Stc1 domain Cpn60_TCP1 PF00118.19 OAJ10223.1 - 1.4e-119 399.9 6.4 1.7e-119 399.6 4.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RRM_5 PF13893.1 OAJ10224.1 - 1.8e-09 37.2 0.0 2.7e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ10224.1 - 2.2e-09 36.7 0.0 8e-09 35.0 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ10224.1 - 0.00062 19.7 0.0 0.0014 18.5 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cpn10 PF00166.16 OAJ10225.1 - 3.1e-25 87.9 0.0 3.5e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit PIF1 PF05970.9 OAJ10230.1 - 1.3e-54 185.6 0.0 1.7e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ10230.1 - 2.8e-31 108.6 0.0 6.2e-31 107.5 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 OAJ10230.1 - 2.1e-06 27.4 0.0 5e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ10230.1 - 0.0018 17.9 0.2 0.0083 15.8 0.2 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 OAJ10230.1 - 0.0031 17.5 0.1 0.028 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 OAJ10230.1 - 0.0076 15.9 0.0 0.02 14.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain DUF2791 PF10923.3 OAJ10230.1 - 0.018 13.6 0.0 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_22 PF13401.1 OAJ10230.1 - 0.049 13.7 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 OAJ10230.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF2075 PF09848.4 OAJ10230.1 - 0.18 10.7 0.0 1.3 7.9 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ALIX_LYPXL_bnd PF13949.1 OAJ10230.1 - 0.44 9.4 0.0 0.7 8.7 0.0 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Collagen PF01391.13 OAJ10240.1 - 4.9e-13 48.4 81.7 0.00017 21.0 12.1 3.8 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) DUF1104 PF06518.6 OAJ10247.1 - 0.032 14.3 2.2 0.097 12.8 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) DUF3682 PF12446.3 OAJ10247.1 - 0.032 14.5 0.4 0.097 12.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) V-ATPase_G PF03179.10 OAJ10248.1 - 0.015 15.6 0.4 0.015 15.6 0.3 2.2 3 0 0 3 3 3 0 Vacuolar (H+)-ATPase G subunit Macoilin PF09726.4 OAJ10248.1 - 4.4 5.4 8.9 5.5 5.1 6.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Helicase_C PF00271.26 OAJ10258.1 - 6.6e-12 45.1 0.0 2.1e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ10258.1 - 5e-11 42.3 0.0 5.9e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ10258.1 - 0.0016 18.2 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit rve PF00665.21 OAJ10259.1 - 2.5e-07 30.8 0.0 4.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DNA_mis_repair PF01119.14 OAJ10264.1 - 3.5e-18 65.1 0.0 8.1e-18 64.0 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain TPR_12 PF13424.1 OAJ10264.1 - 2.4e-12 46.6 0.6 9.7e-05 22.2 0.1 3.5 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ10264.1 - 1.7e-06 27.7 0.0 0.0068 16.2 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ10264.1 - 0.00028 20.4 0.1 0.61 9.7 0.0 3.0 3 0 0 3 3 3 2 TPR repeat DUF3856 PF12968.2 OAJ10264.1 - 0.003 17.3 0.7 0.73 9.6 0.1 2.5 1 1 0 2 2 2 2 Domain of Unknown Function (DUF3856) TPR_14 PF13428.1 OAJ10264.1 - 0.068 13.8 0.6 56 4.7 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Ssu72 PF04722.8 OAJ10264.1 - 0.1 11.9 0.0 0.24 10.6 0.0 1.6 1 0 0 1 1 1 0 Ssu72-like protein Apc5 PF12862.2 OAJ10265.1 - 9.6e-05 22.1 1.3 0.00012 21.8 0.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 DUF1173 PF06666.6 OAJ10265.1 - 0.036 12.8 0.0 0.041 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) ICL PF00463.16 OAJ10265.1 - 0.05 11.8 0.0 0.05 11.8 0.0 1.1 1 0 0 1 1 1 0 Isocitrate lyase family DUF716 PF04819.7 OAJ10265.1 - 0.078 12.4 0.3 0.089 12.2 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF716) Dimer_Tnp_hAT PF05699.9 OAJ10266.1 - 1.7e-10 40.3 0.0 3.4e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Herpes_MCP PF03122.9 OAJ10266.1 - 0.18 9.1 0.2 0.26 8.5 0.1 1.2 1 0 0 1 1 1 0 Herpes virus major capsid protein C2 PF00168.25 OAJ10272.1 - 1.2e-56 188.4 1.0 6.6e-21 73.9 0.0 4.4 4 0 0 4 4 4 4 C2 domain DUF2404 PF10296.4 OAJ10272.1 - 0.0063 16.6 0.0 0.049 13.7 0.0 2.4 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Autophagy_N PF03986.8 OAJ10273.1 - 1.3e-44 151.5 0.0 2.4e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 OAJ10273.1 - 2.3e-28 98.1 0.1 4.7e-28 97.1 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 OAJ10273.1 - 8.9e-12 43.8 0.3 1.5e-11 43.1 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal rve PF00665.21 OAJ10278.1 - 1.4e-05 25.1 0.0 2.7e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.1 OAJ10278.1 - 0.00021 20.8 0.1 0.0012 18.3 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain COG2 PF06148.6 OAJ10278.1 - 0.00041 20.2 0.1 0.001 18.9 0.1 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 HTH_11 PF08279.7 OAJ10278.1 - 0.031 13.9 0.4 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 HTH domain HTH_Crp_2 PF13545.1 OAJ10278.1 - 0.041 13.6 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Phage_NinH PF06322.6 OAJ10278.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.8 1 0 0 1 1 1 0 Phage NinH protein Sigma70_r4_2 PF08281.7 OAJ10278.1 - 0.28 10.6 1.8 0.62 9.5 0.0 2.5 3 0 0 3 3 3 0 Sigma-70, region 4 PHD PF00628.24 OAJ10279.1 - 8.9e-08 31.7 9.2 1.6e-07 30.8 6.4 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 OAJ10279.1 - 1.7 8.4 7.7 4.6 7.0 5.3 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 ubiquitin PF00240.18 OAJ10284.1 - 5.8e-14 51.2 0.1 0.00048 19.4 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 OAJ10284.1 - 0.00044 19.8 0.0 0.03 13.9 0.0 2.9 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like FlgD_ig PF13860.1 OAJ10284.1 - 0.0058 16.3 0.8 0.25 11.0 0.1 2.5 2 0 0 2 2 2 1 FlgD Ig-like domain DUF3244 PF11589.3 OAJ10284.1 - 0.031 13.9 0.4 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3244) MYCBPAP PF14646.1 OAJ10284.1 - 0.11 11.1 0.5 0.15 10.7 0.3 1.1 1 0 0 1 1 1 0 MYCBP-associated protein family DUF4551 PF15087.1 OAJ10284.1 - 0.11 10.7 0.1 0.22 9.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4551) Trypan_PARP PF05887.6 OAJ10284.1 - 0.23 11.2 2.8 0.33 10.7 1.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ubiquitin PF00240.18 OAJ10285.1 - 2.1e-19 68.6 0.0 8.6e-10 37.8 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 OAJ10285.1 - 8.1e-12 44.6 0.1 5.8e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 OAJ10286.1 - 2.8e-09 36.2 0.1 0.00021 20.6 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 OAJ10286.1 - 0.00068 19.2 0.1 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.3 OAJ10286.1 - 0.019 15.2 0.0 1.8 8.9 0.0 2.6 2 1 1 3 3 3 0 Nuclear pore localisation protein NPL4 Hamartin PF04388.7 OAJ10291.1 - 0.49 9.0 6.6 0.68 8.5 4.5 1.1 1 0 0 1 1 1 0 Hamartin protein MFS_1 PF07690.11 OAJ10293.1 - 3e-27 95.2 32.8 4.2e-27 94.8 22.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UPF0193 PF05250.6 OAJ10294.1 - 0.0016 18.0 0.8 0.0021 17.6 0.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) AUX_IAA PF02309.11 OAJ10294.1 - 0.0083 15.8 0.6 0.0091 15.7 0.4 1.1 1 0 0 1 1 1 1 AUX/IAA family TFIIA PF03153.8 OAJ10294.1 - 0.12 12.2 13.3 0.14 12.0 9.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec10 PF07393.6 OAJ10294.1 - 0.13 10.4 5.9 0.14 10.3 4.1 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 DUF4551 PF15087.1 OAJ10294.1 - 0.63 8.3 8.6 0.76 8.0 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Macoilin PF09726.4 OAJ10294.1 - 0.94 7.6 8.4 0.96 7.6 5.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Dicty_REP PF05086.7 OAJ10294.1 - 1 7.0 7.3 1.1 6.9 5.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CENP-U PF13097.1 OAJ10294.1 - 1.2 9.0 9.4 1.6 8.6 6.5 1.2 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit PAT1 PF09770.4 OAJ10294.1 - 2.2 6.4 15.9 2.4 6.2 11.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 OAJ10294.1 - 3 7.1 17.4 3.5 6.9 12.0 1.0 1 0 0 1 1 1 0 Vta1 like GKAP PF03359.8 OAJ10294.1 - 3.1 7.3 12.6 3.6 7.1 8.7 1.1 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Mucin PF01456.12 OAJ10294.1 - 4.8 6.9 15.7 7.2 6.3 10.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein BPL_N PF09825.4 OAJ10297.1 - 3.7e-78 262.8 0.0 5.1e-78 262.4 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 OAJ10297.1 - 1.2e-12 47.9 0.0 2.4e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family NAD_binding_4 PF07993.7 OAJ10298.1 - 1.2e-22 80.0 0.0 4e-22 78.3 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 OAJ10298.1 - 3.6e-14 52.7 0.0 7.4e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 OAJ10298.1 - 1.7e-06 28.0 0.9 0.0016 18.4 0.0 3.1 4 0 0 4 4 4 2 short chain dehydrogenase KR PF08659.5 OAJ10298.1 - 0.00041 20.0 0.4 0.011 15.3 0.1 3.0 2 1 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 OAJ10298.1 - 0.018 13.9 0.0 0.14 10.9 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RVT_2 PF07727.9 OAJ10302.1 - 2.8e-71 239.3 0.0 3.9e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10302.1 - 8e-21 74.3 0.2 2.4e-20 72.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ10302.1 - 1.1e-08 34.6 0.9 9.6e-08 31.5 0.0 2.5 2 0 0 2 2 2 1 GAG-pre-integrase domain UBN2_2 PF14227.1 OAJ10302.1 - 1.8e-06 27.5 0.0 3.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ10302.1 - 7.4e-05 22.5 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ10302.1 - 0.00026 20.7 9.0 0.0011 18.7 1.9 2.5 2 0 0 2 2 2 1 Zinc knuckle rve_3 PF13683.1 OAJ10302.1 - 0.0043 16.5 0.0 0.014 14.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_4 PF14392.1 OAJ10302.1 - 1.1 9.0 5.9 7.5 6.3 0.6 2.5 2 0 0 2 2 2 0 Zinc knuckle Macoilin PF09726.4 OAJ10302.1 - 5.9 5.0 7.1 8.8 4.4 4.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Metallophos PF00149.23 OAJ10307.1 - 4e-41 140.6 0.1 6.5e-41 139.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3306 PF11748.3 OAJ10307.1 - 1.5 9.4 7.3 3 8.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) DUF2486 PF10667.4 OAJ10307.1 - 1.9 8.9 17.7 2.9 8.3 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) GKAP PF03359.8 OAJ10307.1 - 3.5 7.1 16.9 6 6.3 11.7 1.4 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein PAT1 PF09770.4 OAJ10307.1 - 9.4 4.3 32.9 13 3.8 22.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Chorion_2 PF03964.10 OAJ10308.1 - 2 9.0 9.8 0.1 13.1 2.7 2.0 2 1 0 2 2 2 0 Chorion family 2 UQ_con PF00179.21 OAJ10309.1 - 2.9e-42 143.4 0.0 3.2e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ10309.1 - 0.0052 16.5 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B TipAS PF07739.8 OAJ10309.1 - 0.015 15.5 0.0 0.46 10.8 0.0 2.1 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain RWD PF05773.17 OAJ10309.1 - 0.039 13.8 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain DUF3128 PF11326.3 OAJ10310.1 - 0.0007 19.6 0.6 0.0011 19.0 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.12 OAJ10310.1 - 0.0048 16.8 1.8 0.052 13.5 0.1 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 OAJ10310.1 - 0.0068 16.4 0.8 0.01 15.8 0.5 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 OAJ10310.1 - 0.016 14.9 2.1 0.023 14.4 1.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.4 OAJ10310.1 - 0.027 14.4 1.6 0.045 13.7 1.1 1.4 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.8 OAJ10310.1 - 0.63 10.0 8.0 3.9 7.5 1.1 2.1 1 1 1 2 2 2 0 CHCH domain TFIID_90kDa PF04494.10 OAJ10311.1 - 7.2e-31 107.1 0.0 1.6e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit WD40 PF00400.27 OAJ10311.1 - 3.3e-25 86.9 3.2 1.3e-10 40.6 0.1 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat LisH PF08513.6 OAJ10311.1 - 0.0085 15.8 0.0 0.022 14.4 0.0 1.8 1 0 0 1 1 1 1 LisH Mito_fiss_reg PF05308.6 OAJ10319.1 - 0.096 12.0 0.4 2.6 7.3 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator FAD_binding_3 PF01494.14 OAJ10320.1 - 0.0057 15.7 0.0 0.0076 15.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain HSP70 PF00012.15 OAJ10326.1 - 1.5e-46 158.5 0.0 2e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein Methyltransf_8 PF05148.10 OAJ10326.1 - 0.00044 19.9 0.0 0.00077 19.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase MmgE_PrpD PF03972.9 OAJ10327.1 - 8.4e-93 310.9 0.4 9.8e-93 310.7 0.3 1.0 1 0 0 1 1 1 1 MmgE/PrpD family MmgE_PrpD PF03972.9 OAJ10328.1 - 4.4e-09 35.0 0.3 6.1e-09 34.5 0.2 1.3 1 1 0 1 1 1 1 MmgE/PrpD family ADH_zinc_N_2 PF13602.1 OAJ10335.1 - 1.1e-14 55.3 0.0 3.2e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 OAJ10335.1 - 1.6e-13 50.3 0.0 2.8e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DeoRC PF00455.17 OAJ10335.1 - 0.0032 17.1 0.1 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 DeoR C terminal sensor domain ADH_N PF08240.7 OAJ10335.1 - 0.0048 16.6 0.0 0.037 13.7 0.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_4 PF07993.7 OAJ10336.1 - 7e-27 93.9 0.0 2.4e-26 92.2 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 OAJ10336.1 - 1.3e-20 73.2 0.0 3.7e-18 65.1 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 OAJ10336.1 - 1.1e-13 51.2 0.0 2.1e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAJ10336.1 - 2.4e-07 29.7 0.0 2.7e-05 23.0 0.0 2.8 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 OAJ10336.1 - 4.7e-05 23.3 0.5 0.0014 18.5 0.4 2.8 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 OAJ10336.1 - 0.00011 21.1 0.2 0.012 14.5 0.0 2.7 3 0 0 3 3 3 1 RmlD substrate binding domain KR PF08659.5 OAJ10336.1 - 0.00028 20.5 0.1 0.002 17.7 0.1 2.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 OAJ10336.1 - 0.0067 15.3 0.0 0.47 9.3 0.0 2.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein HAD_2 PF13419.1 OAJ10336.1 - 0.04 14.1 0.0 11 6.2 0.0 3.3 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase NmrA PF05368.8 OAJ10336.1 - 0.048 12.8 0.1 8.3 5.5 0.0 2.3 2 0 0 2 2 2 0 NmrA-like family AMP-binding_C PF13193.1 OAJ10336.1 - 0.13 13.2 0.6 0.44 11.5 0.1 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain DUF2051 PF09738.4 OAJ10344.1 - 0.1 11.8 0.7 0.12 11.6 0.5 1.1 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Histone PF00125.19 OAJ10345.1 - 9.1e-29 99.4 0.4 1.4e-28 98.7 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ10345.1 - 9.6e-05 22.4 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAJ10345.1 - 0.013 15.5 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone KAR9 PF08580.5 OAJ10347.1 - 0.9 7.7 7.3 0.99 7.5 5.0 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Period_C PF12114.3 OAJ10347.1 - 3.9 7.0 10.2 7.3 6.1 7.1 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region zf-BED PF02892.10 OAJ10348.1 - 0.00072 19.2 3.0 0.0015 18.2 2.1 1.5 1 0 0 1 1 1 1 BED zinc finger DHQ_synthase PF01761.15 OAJ10354.1 - 8.9e-48 162.4 0.0 1.2e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 OAJ10354.1 - 4.4e-09 36.0 0.0 6.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 OAJ10354.1 - 0.019 13.6 0.0 0.062 11.9 0.0 1.9 1 1 0 1 1 1 0 Iron-containing alcohol dehydrogenase ATPgrasp_Ter PF15632.1 OAJ10355.1 - 1.1e-08 34.2 0.0 2.8e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 OAJ10355.1 - 4.4e-07 29.8 0.0 9.4e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain Abhydrolase_5 PF12695.2 OAJ10355.1 - 0.045 13.4 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ10355.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF1912 PF08930.5 OAJ10356.1 - 0.0066 16.5 0.4 0.027 14.5 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1912) Cas_CT1975 PF09344.5 OAJ10363.1 - 1.1e-62 212.4 3.0 1.2e-62 212.3 2.1 1.0 1 0 0 1 1 1 1 CT1975-like protein Cas_Cas5d PF09704.5 OAJ10364.1 - 2.7e-43 148.1 0.2 3.7e-43 147.6 0.1 1.1 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas5) CRISPR_Cse1 PF09481.5 OAJ10365.1 - 1.4e-104 350.5 0.1 1.6e-104 350.3 0.1 1.0 1 0 0 1 1 1 1 CRISPR-associated protein Cse1 (CRISPR_cse1) CRISPR_Cse2 PF09485.5 OAJ10366.1 - 4.2e-23 81.9 3.0 4.9e-23 81.7 2.1 1.0 1 0 0 1 1 1 1 CRISPR-associated protein Cse2 (CRISPR_cse2) KilA-N PF04383.8 OAJ10367.1 - 1.2e-09 37.7 0.0 1.6e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 KilA-N domain Cas_Cas1 PF01867.11 OAJ10368.1 - 0.011 14.7 0.0 0.011 14.7 0.0 1.0 1 0 0 1 1 1 0 CRISPR associated protein Cas1 ZU5 PF00791.15 OAJ10368.1 - 0.031 13.9 0.1 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 ZU5 domain DEAD PF00270.24 OAJ10369.1 - 1.7e-06 27.6 0.3 5e-05 22.8 0.2 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ10369.1 - 0.0033 17.2 0.1 0.0081 16.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ10369.1 - 0.066 13.0 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Septin PF00735.13 OAJ10376.1 - 1.8e-110 368.4 0.2 2.2e-110 368.1 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 OAJ10376.1 - 1.8e-08 34.2 0.0 5e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 OAJ10376.1 - 6.1e-05 22.2 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 OAJ10376.1 - 0.00019 20.6 1.0 0.00036 19.6 0.0 2.0 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.22 OAJ10376.1 - 0.00048 19.6 0.5 0.0066 15.9 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 OAJ10376.1 - 0.0021 17.5 0.0 0.0055 16.1 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 OAJ10376.1 - 0.0029 17.4 3.3 0.56 10.0 0.1 2.6 2 1 1 3 3 3 2 Dynamin family AAA_10 PF12846.2 OAJ10376.1 - 0.018 14.4 0.2 0.035 13.5 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain T2SE PF00437.15 OAJ10376.1 - 0.027 13.3 0.0 0.056 12.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 OAJ10376.1 - 0.027 14.7 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 OAJ10376.1 - 0.1 12.7 0.0 0.27 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 OAJ10376.1 - 0.11 13.3 2.2 13 6.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 OAJ10376.1 - 0.12 12.3 0.5 2.9 7.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 OAJ10376.1 - 2.5 8.3 6.0 11 6.2 4.2 2.0 1 1 0 1 1 1 0 AAA domain DUF4601 PF15373.1 OAJ10377.1 - 0.059 12.2 0.1 0.078 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) Ion_trans PF00520.26 OAJ10378.1 - 2.3e-06 26.9 8.6 9.8e-05 21.6 5.9 2.2 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 OAJ10378.1 - 0.00018 20.0 14.5 0.0038 15.7 4.1 2.3 3 0 0 3 3 3 2 Polycystin cation channel HALZ PF02183.13 OAJ10378.1 - 0.037 13.7 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper PACT_coil_coil PF10495.4 OAJ10385.1 - 1.6e-11 43.9 0.1 6.1e-11 42.0 0.1 2.1 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.4 OAJ10385.1 - 0.0074 16.1 87.1 0.59 9.9 2.2 6.3 3 1 3 6 6 6 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 OAJ10385.1 - 0.011 14.9 14.4 0.037 13.2 0.8 4.7 2 2 1 5 5 5 0 Reovirus sigma C capsid protein GAS PF13851.1 OAJ10385.1 - 1.3 8.1 75.8 0.023 13.8 8.0 5.1 3 2 1 4 4 4 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.6 OAJ10385.1 - 3.9 7.3 25.4 2.9 7.7 0.3 6.5 6 2 2 8 8 8 0 Bacterial protein of unknown function (DUF948) HrpB2 PF09487.5 OAJ10385.1 - 5.3 7.2 9.2 14 5.9 0.3 3.5 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB2) APG6 PF04111.7 OAJ10385.1 - 6.5 5.6 76.4 0.017 14.1 4.3 5.2 1 1 4 5 5 5 0 Autophagy protein Apg6 Collagen PF01391.13 OAJ10386.1 - 3.4e-20 71.3 72.0 2.4e-08 33.3 15.9 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) 2OG-FeII_Oxy_3 PF13640.1 OAJ10387.1 - 3.4e-09 37.0 0.0 6.2e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 OAJ10387.1 - 1.9e-06 27.3 0.0 4.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Exc PF07825.6 OAJ10387.1 - 0.097 12.4 0.1 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Excisionase-like protein Kelch_4 PF13418.1 OAJ10392.1 - 0.0014 18.3 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_5 PF13854.1 OAJ10392.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Kelch motif ADIP PF11559.3 OAJ10393.1 - 0.09 12.6 5.0 0.076 12.9 2.2 1.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF342 PF03961.8 OAJ10393.1 - 0.1 11.0 0.1 0.12 10.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fis1_TPR_C PF14853.1 OAJ10393.1 - 0.12 12.2 0.2 0.37 10.7 0.1 1.9 1 1 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat LcrG PF07216.7 OAJ10393.1 - 0.14 12.2 1.6 0.23 11.4 1.1 1.4 1 0 0 1 1 1 0 LcrG protein CHDCT2 PF08074.6 OAJ10393.1 - 0.22 11.2 1.5 0.27 10.9 1.0 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain RVT_1 PF00078.22 OAJ10399.1 - 1e-07 31.5 0.0 1.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ10400.1 - 2.3e-08 34.4 0.1 5.2e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ10400.1 - 1.5e-05 24.6 0.0 4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Rad60-SLD PF11976.3 OAJ10400.1 - 2.2e-05 24.0 0.3 4.5 7.0 0.0 4.2 4 0 0 4 4 4 3 Ubiquitin-2 like Rad60 SUMO-like RVP PF00077.15 OAJ10400.1 - 0.0011 18.8 0.0 0.0029 17.5 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 OAJ10400.1 - 0.0043 16.6 0.0 0.0088 15.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.3 OAJ10400.1 - 0.042 13.1 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase Seipin PF06775.9 OAJ10400.1 - 0.063 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative adipose-regulatory protein (Seipin) zf-CCHC PF00098.18 OAJ10400.1 - 1.5 8.8 5.0 2.8 8.0 3.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Phostensin_N PF13916.1 OAJ10407.1 - 0.057 13.4 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal PAT1 PF09770.4 OAJ10413.1 - 1.7e-12 46.4 0.0 2.7e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SdpI PF13630.1 OAJ10413.1 - 0.011 15.4 0.3 0.021 14.4 0.2 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family CitMHS PF03600.11 OAJ10413.1 - 0.036 12.6 0.3 0.052 12.1 0.2 1.2 1 0 0 1 1 1 0 Citrate transporter PAT1 PF09770.4 OAJ10414.1 - 0.054 11.7 4.9 1.5 6.9 3.4 2.0 1 1 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mg_trans_NIPA PF05653.9 OAJ10415.1 - 1.3e-26 93.2 6.9 3.6e-14 52.4 2.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Tetraspannin PF00335.15 OAJ10415.1 - 0.073 12.3 11.3 4.5 6.4 0.1 3.1 2 1 1 3 3 3 0 Tetraspanin family DUF572 PF04502.8 OAJ10416.1 - 4.5 6.3 6.2 9.4 5.3 4.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) AAA PF00004.24 OAJ10418.1 - 1.5e-26 93.1 0.0 2.1e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ10418.1 - 2.9e-06 27.4 0.2 0.085 13.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 OAJ10418.1 - 1.1e-05 25.4 0.4 0.0001 22.3 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 OAJ10418.1 - 0.00035 20.2 0.2 0.0023 17.6 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 OAJ10418.1 - 0.00047 19.6 1.4 0.0089 15.4 1.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAJ10418.1 - 0.0011 18.6 0.0 0.0027 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 OAJ10418.1 - 0.0023 17.8 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ10418.1 - 0.0025 18.6 0.0 0.0041 17.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 OAJ10418.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 OAJ10418.1 - 0.017 14.7 0.9 0.25 10.8 0.6 2.3 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 OAJ10418.1 - 0.022 14.7 0.0 0.037 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 OAJ10418.1 - 0.025 13.3 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 OAJ10418.1 - 0.036 13.6 0.0 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 OAJ10418.1 - 0.049 12.6 0.0 0.073 12.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Miro PF08477.8 OAJ10418.1 - 0.051 14.0 0.0 0.15 12.5 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein Arch_ATPase PF01637.13 OAJ10418.1 - 0.058 13.0 0.1 0.64 9.6 0.1 2.0 1 1 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 OAJ10418.1 - 0.088 13.1 0.0 0.15 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 OAJ10418.1 - 0.095 12.2 0.0 0.13 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain IPT PF01745.11 OAJ10418.1 - 0.12 11.5 0.1 0.34 10.0 0.0 1.6 2 0 0 2 2 2 0 Isopentenyl transferase ANF_receptor PF01094.23 OAJ10418.1 - 0.12 11.0 0.3 1.4 7.6 0.2 2.0 1 1 0 1 1 1 0 Receptor family ligand binding region FimP PF09766.4 OAJ10419.1 - 0.002 17.2 1.0 0.0026 16.9 0.7 1.2 1 0 0 1 1 1 1 Fms-interacting protein DUF2457 PF10446.4 OAJ10419.1 - 0.013 14.2 12.3 0.019 13.7 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleo_P87 PF07267.6 OAJ10419.1 - 0.17 10.5 8.5 0.24 10.0 5.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nucleoplasmin PF03066.10 OAJ10419.1 - 0.2 11.1 7.2 0.32 10.4 5.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 OAJ10419.1 - 0.99 8.9 13.8 1.6 8.2 9.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.6 OAJ10419.1 - 2.7 6.0 4.7 3.1 5.8 3.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 OAJ10419.1 - 4.5 5.1 13.9 6.6 4.6 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 OAJ10419.1 - 5.4 6.9 11.2 9.3 6.2 7.7 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.1 OAJ10419.1 - 7.9 6.1 6.6 16 5.1 4.6 1.5 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 OAJ10419.1 - 8.7 6.7 15.9 19 5.6 11.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 OAJ10419.1 - 9.3 5.4 9.6 12 5.1 6.7 1.1 1 0 0 1 1 1 0 NOA36 protein Helitron_like_N PF14214.1 OAJ10425.1 - 4.9e-35 120.9 0.2 4.9e-35 120.9 0.2 2.2 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus DUF747 PF05346.6 OAJ10426.1 - 4e-111 371.2 0.0 3.6e-99 331.9 0.2 2.0 2 0 0 2 2 2 2 Eukaryotic membrane protein family Kinesin PF00225.18 OAJ10428.1 - 1.8e-71 240.5 0.5 3.4e-43 147.6 0.0 2.9 3 0 0 3 3 3 2 Kinesin motor domain DUF4611 PF15387.1 OAJ10429.1 - 5.7 7.1 27.4 6.1 7.0 4.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Pkinase PF00069.20 OAJ10432.1 - 1.8e-64 217.4 0.0 2.2e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ10432.1 - 4.9e-38 130.6 0.0 8.1e-37 126.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ10432.1 - 0.00078 18.4 0.0 0.0029 16.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAJ10432.1 - 0.074 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ10432.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 OAJ10432.1 - 0.11 11.8 0.1 0.42 9.9 0.0 1.8 1 1 1 2 2 2 0 RIO1 family Mito_carr PF00153.22 OAJ10433.1 - 6.5e-70 230.9 13.6 1.2e-23 82.6 0.1 5.2 4 1 0 4 4 4 4 Mitochondrial carrier protein ERG4_ERG24 PF01222.12 OAJ10434.1 - 9.2e-120 400.0 22.0 1.1e-119 399.8 15.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family RVT_1 PF00078.22 OAJ10439.1 - 1.8e-16 60.1 0.0 3.6e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10439.1 - 1.1e-14 54.5 0.0 9e-14 51.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ10439.1 - 0.0017 18.7 0.2 0.0059 17.0 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ10439.1 - 0.015 15.0 0.1 0.075 12.8 0.1 2.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ10439.1 - 0.081 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.12 OAJ10440.1 - 0.089 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.22 OAJ10447.1 - 5.3e-16 58.6 0.0 9.9e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ10447.1 - 0.00035 21.0 0.0 0.00092 19.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease TAFH PF07531.9 OAJ10447.1 - 0.076 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 NHR1 homology to TAF RVP PF00077.15 OAJ10447.1 - 0.27 11.1 0.0 0.74 9.7 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease CbiC PF02570.10 OAJ10451.1 - 0.069 12.5 0.2 0.12 11.8 0.1 1.3 1 1 0 1 1 1 0 Precorrin-8X methylmutase DUF1542 PF07564.6 OAJ10451.1 - 0.094 12.7 1.7 0.2 11.7 1.1 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1542) Transferase PF02458.10 OAJ10453.1 - 0.00019 20.0 0.0 0.46 8.8 0.0 2.7 3 0 0 3 3 3 2 Transferase family DEAD PF00270.24 OAJ10454.1 - 1.8e-46 157.7 0.0 3.1e-46 156.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ10454.1 - 7.5e-27 93.0 0.0 1.7e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ10454.1 - 0.019 14.7 0.0 0.054 13.3 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit HeH PF12949.2 OAJ10462.1 - 0.028 13.9 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 HeH/LEM domain DUF3136 PF11334.3 OAJ10462.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) TctB PF07331.6 OAJ10462.1 - 5.9 6.5 7.5 11 5.7 0.1 2.8 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family DUF3040 PF11239.3 OAJ10462.1 - 7.6 6.6 5.9 8.6 6.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF3136 PF11334.3 OAJ10463.1 - 0.052 12.9 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) SipA PF09052.5 OAJ10463.1 - 0.075 11.4 2.3 0.12 10.7 1.6 1.2 1 0 0 1 1 1 0 Salmonella invasion protein A MIP-T3 PF10243.4 OAJ10470.1 - 1 7.7 48.0 1.5 7.2 33.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 OAJ10472.1 - 0.0025 15.8 26.6 0.0032 15.5 18.4 1.2 1 0 0 1 1 1 1 Nop14-like family Pox_Ag35 PF03286.9 OAJ10472.1 - 0.033 13.7 18.5 0.055 12.9 12.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC27 PF09507.5 OAJ10472.1 - 0.12 11.5 21.5 0.2 10.8 14.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nucleo_P87 PF07267.6 OAJ10472.1 - 0.16 10.6 5.2 0.17 10.5 3.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 IFT57 PF10498.4 OAJ10472.1 - 0.16 10.6 11.1 0.27 9.9 7.0 1.8 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Daxx PF03344.10 OAJ10472.1 - 0.37 9.2 34.8 0.53 8.7 24.1 1.1 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 OAJ10472.1 - 0.53 7.9 4.4 0.54 7.8 3.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2457 PF10446.4 OAJ10472.1 - 0.64 8.6 38.5 1.1 7.9 26.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RR_TM4-6 PF06459.7 OAJ10472.1 - 0.66 9.8 13.1 1.1 9.0 9.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.8 OAJ10472.1 - 0.67 8.4 5.6 0.86 8.0 3.9 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NARP1 PF12569.3 OAJ10472.1 - 0.82 8.3 12.9 1.3 7.6 9.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ycf1 PF05758.7 OAJ10472.1 - 1 7.0 10.8 1.3 6.6 7.5 1.2 1 0 0 1 1 1 0 Ycf1 CobT PF06213.7 OAJ10472.1 - 2.1 7.3 33.8 4 6.4 23.4 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.5 OAJ10472.1 - 2.3 7.2 41.6 11 4.9 28.8 1.9 1 1 0 1 1 1 0 BUD22 Astro_capsid PF03115.9 OAJ10472.1 - 2.6 6.1 9.8 3.7 5.6 6.8 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF1510 PF07423.6 OAJ10472.1 - 4.6 6.5 28.6 9.2 5.5 19.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 OAJ10472.1 - 5.1 6.2 34.1 9.9 5.3 23.6 1.4 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.7 OAJ10472.1 - 6.8 5.3 6.3 2.3 6.8 2.6 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RNA_pol_3_Rpc31 PF11705.3 OAJ10472.1 - 7.1 6.5 34.3 6.6 6.5 22.9 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Tim54 PF11711.3 OAJ10472.1 - 7.6 5.0 13.0 12 4.4 9.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CENP-T PF15511.1 OAJ10472.1 - 8.6 5.4 22.4 12 4.9 15.5 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 OAJ10472.1 - 9.2 4.1 25.9 14 3.6 18.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.22 OAJ10477.1 - 0.0024 17.2 0.0 0.0068 15.7 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 OAJ10477.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Phage_integrase PF00589.17 OAJ10478.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family HEAT_EZ PF13513.1 OAJ10479.1 - 1.2e-10 41.5 18.3 0.047 14.2 0.1 6.9 5 2 3 8 8 8 4 HEAT-like repeat HEAT PF02985.17 OAJ10479.1 - 2.2e-06 27.2 12.6 4.4 7.6 0.0 8.3 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.1 OAJ10479.1 - 0.00059 20.0 19.9 0.04 14.2 0.6 5.8 3 2 4 7 7 7 3 HEAT repeats DUF3647 PF12363.3 OAJ10479.1 - 0.0038 17.3 0.1 0.086 12.9 0.0 2.7 3 0 0 3 3 3 1 Phage protein ParcG PF10274.4 OAJ10479.1 - 0.0045 16.9 0.0 0.066 13.0 0.0 2.7 3 1 0 3 3 3 1 Parkin co-regulated protein zf-CCHC_4 PF14392.1 OAJ10483.1 - 2.7 7.7 7.0 1 9.0 0.8 2.4 2 0 0 2 2 2 0 Zinc knuckle TFIIA PF03153.8 OAJ10483.1 - 3.4 7.4 19.0 0.3 10.9 4.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Rac1 PF09632.5 OAJ10484.1 - 0.071 12.1 0.0 0.087 11.8 0.0 1.1 1 0 0 1 1 1 0 Rac1-binding domain Phage_integrase PF00589.17 OAJ10485.1 - 0.00094 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Tyrosinase PF00264.15 OAJ10490.1 - 1e-27 97.7 0.0 1.5e-27 97.2 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Spt4 PF06093.8 OAJ10498.1 - 2.7e-29 100.8 0.1 3.1e-29 100.6 0.1 1.0 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Integrin_B_tail PF07965.7 OAJ10498.1 - 0.076 13.4 1.3 0.11 12.9 0.9 1.2 1 0 0 1 1 1 0 Integrin beta tail domain DZR PF12773.2 OAJ10498.1 - 0.078 12.8 1.5 0.13 12.0 1.0 1.3 1 0 0 1 1 1 0 Double zinc ribbon MIF4G_like PF09088.6 OAJ10499.1 - 2.8e-59 199.7 0.0 1.4e-58 197.4 0.0 2.1 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 OAJ10499.1 - 1e-34 119.8 0.4 2.5e-29 102.2 0.0 3.1 2 1 0 2 2 2 2 MIF4G like GKAP PF03359.8 OAJ10499.1 - 0.00026 20.7 0.4 0.0005 19.8 0.3 1.4 1 0 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein Skp1 PF01466.14 OAJ10500.1 - 7e-37 125.3 1.1 7e-37 125.3 0.7 1.6 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 OAJ10500.1 - 2.1e-17 62.9 0.0 4.2e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain UPF0081 PF03652.10 OAJ10508.1 - 0.015 15.4 0.3 0.028 14.5 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) Macoilin PF09726.4 OAJ10508.1 - 7.5 4.6 12.6 9.4 4.3 8.7 1.1 1 0 0 1 1 1 0 Transmembrane protein TRAPP PF04051.11 OAJ10519.1 - 7.9e-36 122.8 0.0 1.2e-35 122.2 0.0 1.3 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component MSP1_C PF07462.6 OAJ10519.1 - 5.3 5.2 5.1 7.3 4.8 3.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RNase_H PF00075.19 OAJ10520.1 - 2.4e-12 47.3 0.0 4.5e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 OAJ10520.1 - 3.5e-12 46.1 0.0 6.1e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAJ10521.1 - 0.0025 17.2 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ10521.1 - 0.058 13.0 0.0 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase zf-CCHC_4 PF14392.1 OAJ10522.1 - 0.089 12.4 8.8 0.57 9.8 1.5 2.5 1 1 1 2 2 2 0 Zinc knuckle VESA1_N PF12785.2 OAJ10522.1 - 6.1 5.6 12.1 6.5 5.5 8.4 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 SOBP PF15279.1 OAJ10523.1 - 6.5 7.0 6.9 8.9 6.5 4.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein ApbA PF02558.11 OAJ10524.1 - 4.5e-27 94.3 0.0 7e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 OAJ10524.1 - 2.5e-26 92.1 0.0 5.9e-26 90.9 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal DAO PF01266.19 OAJ10524.1 - 0.0022 16.9 0.2 0.006 15.5 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAJ10524.1 - 0.036 13.1 0.0 0.064 12.2 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain ThiF PF00899.16 OAJ10524.1 - 0.064 13.0 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.22 OAJ10524.1 - 0.15 12.4 0.1 0.36 11.2 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 OAJ10529.1 - 1.1e-42 145.1 0.0 1.9e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 OAJ10529.1 - 2.3e-27 94.3 0.1 4.5e-27 93.4 0.1 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 OAJ10529.1 - 3.9e-21 74.1 3.2 9.4e-21 72.9 2.2 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 OAJ10529.1 - 1.3e-05 25.2 0.2 0.00048 20.1 0.1 2.6 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 OAJ10529.1 - 0.00064 19.8 0.2 0.0025 17.9 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 OAJ10529.1 - 0.071 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 OAJ10529.1 - 0.11 12.9 0.1 0.37 11.2 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FXR1P_C PF12235.3 OAJ10536.1 - 1.6 8.8 18.4 0.29 11.2 8.7 2.6 2 1 1 3 3 3 0 Fragile X-related 1 protein C terminal Transposase_21 PF02992.9 OAJ10538.1 - 2.6e-11 43.0 0.1 4.3e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 RVT_1 PF00078.22 OAJ10543.1 - 6.4e-25 87.7 0.1 1.4e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10543.1 - 2.6e-20 72.7 0.0 2.1e-19 69.7 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain Retrotrans_gag PF03732.12 OAJ10543.1 - 5.5e-09 35.9 0.7 3.2e-08 33.5 0.0 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein RVP_2 PF08284.6 OAJ10543.1 - 0.00018 21.4 0.0 0.00053 19.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAJ10543.1 - 0.00023 21.6 0.0 0.00058 20.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ10543.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DEAD PF00270.24 OAJ10549.1 - 4.8e-39 133.5 0.0 7.7e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ10549.1 - 1.1e-23 82.9 0.0 2.7e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ10549.1 - 0.013 15.2 0.0 0.064 13.0 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DNA_pol_E_B PF04042.11 OAJ10550.1 - 7.3e-29 100.5 0.3 1.1e-28 99.9 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 OAJ10550.1 - 4.1e-18 65.8 0.0 8.9e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal GMC_oxred_N PF00732.14 OAJ10551.1 - 9e-51 172.7 0.9 2.6e-49 167.9 0.6 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ10551.1 - 4.9e-30 104.7 0.0 8.9e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 OAJ10551.1 - 2.2e-06 26.7 0.1 0.00016 20.6 0.0 3.0 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 OAJ10551.1 - 4.6e-06 26.5 0.1 1.2e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAJ10551.1 - 2.3e-05 23.4 0.0 3.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 OAJ10551.1 - 0.00018 20.5 0.1 0.0003 19.8 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAJ10551.1 - 0.011 14.8 0.1 0.023 13.7 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 OAJ10551.1 - 0.013 15.3 0.1 0.013 15.3 0.1 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ10551.1 - 0.015 14.4 0.1 0.029 13.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 OAJ10551.1 - 0.034 12.6 0.1 0.079 11.4 0.1 1.6 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 OAJ10551.1 - 0.035 13.8 0.3 0.087 12.5 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 OAJ10551.1 - 0.056 13.4 0.1 0.25 11.3 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain TPR_1 PF00515.23 OAJ10559.1 - 1.6e-28 97.1 11.0 1.6e-05 24.3 0.0 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ10559.1 - 1e-25 87.5 15.8 1.8e-05 24.2 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ10559.1 - 1.4e-25 88.7 13.0 6.8e-09 35.2 0.1 6.4 4 1 2 6 6 6 5 TPR repeat TPR_8 PF13181.1 OAJ10559.1 - 7e-24 81.7 6.5 7.9e-05 22.1 0.0 8.7 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ10559.1 - 6.4e-16 57.4 25.7 0.0027 18.2 0.1 10.3 6 4 5 11 11 9 4 Tetratricopeptide repeat APC8 PF04049.8 OAJ10559.1 - 1.2e-15 57.4 3.1 3.1e-14 52.8 2.2 2.4 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_17 PF13431.1 OAJ10559.1 - 5.9e-15 54.1 6.8 0.00092 19.2 0.0 8.0 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ10559.1 - 1.4e-13 50.5 19.8 0.00025 20.9 0.0 7.7 4 3 4 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 OAJ10559.1 - 7.3e-13 48.4 8.7 0.0063 16.6 0.1 4.6 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 OAJ10559.1 - 1.5e-10 41.4 26.4 0.00074 20.1 0.0 8.2 6 2 2 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ10559.1 - 1.5e-10 40.0 13.3 0.00015 21.3 0.0 6.6 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ10559.1 - 7.3e-10 39.0 9.9 0.019 15.2 0.0 7.3 6 1 0 6 6 6 2 Tetratricopeptide repeat ChAPs PF09295.5 OAJ10559.1 - 6.9e-05 21.7 0.0 0.036 12.8 0.0 3.0 2 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.1 OAJ10559.1 - 0.0003 21.0 17.9 10 6.8 0.0 9.5 10 1 1 11 11 10 0 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ10559.1 - 0.00047 19.9 13.0 1.4 8.8 0.4 5.8 3 1 2 6 6 5 1 Tetratricopeptide repeat RPN7 PF10602.4 OAJ10559.1 - 0.052 12.9 0.7 2.2 7.6 0.1 2.5 2 0 0 2 2 2 0 26S proteasome subunit RPN7 YfiO PF13525.1 OAJ10559.1 - 0.058 12.8 1.5 0.15 11.4 0.0 2.6 4 0 0 4 4 4 0 Outer membrane lipoprotein PPR PF01535.15 OAJ10559.1 - 0.29 11.2 1.8 15 5.8 0.0 3.8 5 0 0 5 5 4 0 PPR repeat SNF2_N PF00176.18 OAJ10560.1 - 3.7e-60 203.2 0.0 5.2e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ10560.1 - 1.6e-13 50.2 0.0 4.4e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ10560.1 - 3.2e-08 33.2 0.0 8.6e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ10560.1 - 8.3e-06 25.7 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 OAJ10560.1 - 6.5e-05 21.8 0.0 0.00015 20.6 0.0 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2075 PF09848.4 OAJ10560.1 - 0.056 12.4 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Response_reg PF00072.19 OAJ10564.1 - 3.1e-22 78.6 0.1 5.8e-16 58.4 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain DUF89 PF01937.14 OAJ10565.1 - 2.4e-109 365.3 0.0 2.7e-109 365.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF2051 PF09738.4 OAJ10574.1 - 0.0041 16.4 0.4 0.0052 16.1 0.3 1.2 1 0 0 1 1 1 1 Double stranded RNA binding protein (DUF2051) RVT_2 PF07727.9 OAJ10575.1 - 7e-79 264.2 0.0 1.4e-78 263.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10575.1 - 4.7e-20 71.8 0.0 2e-19 69.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 OAJ10575.1 - 6.2e-17 61.2 0.1 5.9e-16 58.1 0.1 2.2 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ10575.1 - 2.4e-11 43.4 0.3 5.8e-11 42.2 0.2 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 OAJ10575.1 - 9.9e-07 28.4 0.0 2.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAJ10575.1 - 1.3e-06 27.9 0.0 2.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.1 OAJ10575.1 - 0.00031 20.0 0.0 0.0011 18.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) RVP PF00077.15 OAJ10575.1 - 0.002 18.0 0.0 0.0055 16.5 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.18 OAJ10575.1 - 0.18 11.7 5.4 0.42 10.6 3.7 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF4345 PF14248.1 OAJ10583.1 - 0.1 12.0 0.7 0.64 9.4 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) Response_reg PF00072.19 OAJ10584.1 - 4.3e-07 29.9 0.0 1.4e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain E3_binding PF02817.12 OAJ10585.1 - 8.2e-10 38.1 0.1 1.6e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 e3 binding domain Peptidase_C65 PF10275.4 OAJ10586.1 - 5.7e-60 202.6 0.0 7.3e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 OAJ10586.1 - 1.5e-05 25.5 0.0 8.8e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 OTU-like cysteine protease TPMT PF05724.6 OAJ10587.1 - 1.4e-33 116.2 0.0 1.7e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 OAJ10587.1 - 1.9e-09 37.3 0.0 2.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ10587.1 - 7.4e-09 36.1 0.0 1.3e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ10587.1 - 6.8e-08 32.8 0.0 1e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ10587.1 - 2.8e-06 27.7 0.0 6.6e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ10587.1 - 4e-06 26.8 0.0 8.9e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ10587.1 - 1.1e-05 25.6 0.0 1.6e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ10587.1 - 5.4e-05 22.9 0.0 7.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 OAJ10587.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB Mitofilin PF09731.4 OAJ10595.1 - 0.04 12.5 49.7 0.058 12.0 18.0 2.2 2 0 0 2 2 2 0 Mitochondrial inner membrane protein NPV_P10 PF05531.7 OAJ10595.1 - 0.93 9.7 11.3 1 9.6 0.0 4.4 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.6 OAJ10595.1 - 1.4 6.3 4.4 2 5.8 3.1 1.2 1 0 0 1 1 1 0 Prominin TRAUB PF08164.7 OAJ10596.1 - 1.1e-22 79.9 0.0 8.9e-22 77.0 0.0 2.6 1 1 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 OAJ10596.1 - 5.1e-08 33.1 9.4 3.9e-07 30.2 4.0 2.9 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor Pkinase PF00069.20 OAJ10597.1 - 9.3e-70 234.7 0.0 1.3e-69 234.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ10597.1 - 7.7e-35 120.2 0.0 1.1e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CDC27 PF09507.5 OAJ10597.1 - 0.0043 16.3 9.7 0.0043 16.3 6.7 2.4 2 0 0 2 2 2 1 DNA polymerase subunit Cdc27 DUF1777 PF08648.7 OAJ10597.1 - 0.0088 15.7 51.7 0.0088 15.7 35.8 5.9 4 2 2 6 6 6 2 Protein of unknown function (DUF1777) Kinase-like PF14531.1 OAJ10597.1 - 0.02 13.8 0.0 0.071 12.0 0.0 1.7 2 0 0 2 2 2 0 Kinase-like MIP-T3 PF10243.4 OAJ10597.1 - 0.14 10.6 62.4 0.0028 16.1 13.0 2.7 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 zf-CCHC PF00098.18 OAJ10603.1 - 7.8e-05 22.4 2.6 0.00013 21.7 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 OAJ10603.1 - 0.0003 20.2 4.1 0.0013 18.1 2.5 2.2 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 OAJ10603.1 - 0.00033 20.3 1.8 0.00084 19.0 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 OAJ10603.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type TIP_N PF12457.3 OAJ10603.1 - 0.75 9.8 5.3 1.5 8.9 3.7 1.5 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal RVT_2 PF07727.9 OAJ10605.1 - 4.4e-89 297.6 0.0 6.6e-89 297.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10605.1 - 1.7e-26 92.6 0.1 6.5e-26 90.8 0.1 2.1 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ10605.1 - 8.2e-06 25.3 0.0 2.6e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ10605.1 - 0.0009 18.7 0.0 0.0023 17.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain GMC_oxred_N PF00732.14 OAJ10612.1 - 1.1e-49 169.2 0.0 1.4e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ10612.1 - 3.1e-35 121.5 0.1 5.2e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAJ10612.1 - 4.1e-06 25.9 0.4 0.00028 19.9 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ10612.1 - 0.00013 21.0 1.0 0.0047 15.8 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 OAJ10612.1 - 0.00022 21.1 0.7 0.00059 19.8 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAJ10612.1 - 0.0026 16.7 0.2 0.004 16.1 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAJ10612.1 - 0.014 15.4 0.9 1.7 8.6 0.3 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ10612.1 - 0.015 15.2 0.2 0.084 12.7 0.1 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAJ10612.1 - 0.053 12.5 0.1 0.091 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain RVT_1 PF00078.22 OAJ10614.1 - 1.6e-29 102.7 0.0 2.9e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Motile_Sperm PF00635.21 OAJ10617.1 - 3.6e-25 87.7 0.1 6.9e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain FixG_C PF11614.3 OAJ10617.1 - 0.0062 16.6 0.1 0.017 15.2 0.1 1.7 1 0 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Golgin_A5 PF09787.4 OAJ10617.1 - 3.3 6.1 6.0 7 5.0 4.1 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 Tcp11 PF05794.8 OAJ10618.1 - 7.7e-61 206.1 0.2 4.8e-45 154.0 0.6 5.0 4 1 0 4 4 4 4 T-complex protein 11 zf-DHHC PF01529.15 OAJ10630.1 - 4.9e-32 110.7 3.6 5.4e-32 110.5 1.6 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase FA_desaturase PF00487.19 OAJ10630.1 - 0.043 13.2 0.3 2 7.8 0.0 2.3 2 0 0 2 2 2 0 Fatty acid desaturase DEAD PF00270.24 OAJ10636.1 - 2.2e-12 46.8 0.0 6.7e-12 45.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ10636.1 - 5.5e-07 29.3 0.0 7e-06 25.8 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Podoplanin PF05808.6 OAJ10638.1 - 0.36 10.3 6.9 0.62 9.5 4.8 1.3 1 0 0 1 1 1 0 Podoplanin Ifi-6-16 PF06140.8 OAJ10646.1 - 1.8 8.3 6.3 18 5.1 2.1 2.5 2 0 0 2 2 2 0 Interferon-induced 6-16 family Cupin_8 PF13621.1 OAJ10654.1 - 2.3e-46 158.3 0.3 3.4e-26 92.2 0.0 4.3 3 1 0 4 4 4 2 Cupin-like domain VPS9 PF02204.13 OAJ10655.1 - 4.3e-18 65.2 0.0 6.9e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Transposase_21 PF02992.9 OAJ10663.1 - 2.5e-16 59.4 0.0 5.2e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 NAM-associated PF14303.1 OAJ10665.1 - 0.11 12.7 4.2 0.28 11.5 2.9 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain PIF1 PF05970.9 OAJ10671.1 - 1.3e-17 63.8 0.0 2.2e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ10671.1 - 4.1e-12 46.0 0.2 1.4e-11 44.3 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ10671.1 - 1.2e-07 31.3 0.1 4.2e-07 29.6 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain Helitron_like_N PF14214.1 OAJ10671.1 - 0.0032 17.2 0.0 0.01 15.5 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_16 PF13191.1 OAJ10671.1 - 0.0039 17.2 0.1 0.022 14.7 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ10671.1 - 0.062 13.4 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 OAJ10671.1 - 0.067 13.2 0.1 0.64 10.0 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ10671.1 - 0.095 12.4 0.3 0.65 9.7 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Torsin PF06309.6 OAJ10671.1 - 0.13 12.1 0.0 0.46 10.3 0.0 1.9 1 0 0 1 1 1 0 Torsin DUF2075 PF09848.4 OAJ10671.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Matrilin_ccoil PF10393.4 OAJ10677.1 - 0.16 11.3 0.5 0.4 10.0 0.2 1.7 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin PAP_central PF04928.12 OAJ10685.1 - 1.2e-92 309.3 0.0 1.6e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 OAJ10685.1 - 1.2e-40 138.6 0.0 2.3e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 OAJ10685.1 - 3.3e-09 36.9 0.0 8.9e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 OAJ10685.1 - 0.049 11.1 0.0 0.07 10.6 0.0 1.1 1 0 0 1 1 1 0 Nrap protein Arrestin_N PF00339.24 OAJ10686.1 - 9.2e-05 22.2 0.1 0.00049 19.9 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain YABBY PF04690.8 OAJ10687.1 - 2.5e-07 31.1 0.9 3.2e-07 30.7 0.6 1.2 1 1 0 1 1 1 1 YABBY protein HMG_box PF00505.14 OAJ10687.1 - 6.4e-05 23.1 0.5 8.4e-05 22.7 0.3 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ10687.1 - 0.017 15.5 0.3 0.023 15.0 0.2 1.2 1 0 0 1 1 1 0 HMG-box domain IER PF05760.7 OAJ10687.1 - 0.21 11.5 1.5 0.22 11.4 1.1 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Ribosomal_L34 PF00468.12 OAJ10692.1 - 1.4e-17 63.0 9.5 2.1e-17 62.4 6.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 SNF2_N PF00176.18 OAJ10693.1 - 1.8e-46 158.3 0.0 3.1e-46 157.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ10693.1 - 9.5e-13 47.8 0.0 4.7e-11 42.4 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ10693.1 - 0.00019 20.9 0.0 0.00042 19.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ10693.1 - 0.00021 21.1 0.7 0.0013 18.6 0.0 2.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit GDA1_CD39 PF01150.12 OAJ10694.1 - 8.5e-98 327.6 0.0 1.2e-97 327.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Pkinase_Tyr PF07714.12 OAJ10699.1 - 1.9e-08 33.6 0.0 3e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 OAJ10699.1 - 5.5e-08 32.2 0.0 4.2e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain EI24 PF07264.6 OAJ10706.1 - 0.019 14.4 9.3 0.044 13.1 6.5 1.8 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF3270 PF11674.3 OAJ10706.1 - 0.077 13.0 1.3 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) Amino_oxidase PF01593.19 OAJ10707.1 - 2.2e-45 155.5 2.2 3.4e-44 151.6 1.5 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAJ10707.1 - 7.6e-13 48.2 1.2 2.4e-12 46.6 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ10707.1 - 2.3e-07 30.0 0.4 0.00011 21.1 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 OAJ10707.1 - 5.8e-07 28.3 0.9 0.00039 19.0 0.4 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 OAJ10707.1 - 2.2e-06 26.7 1.0 3.7e-06 26.0 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 OAJ10707.1 - 5.2e-05 23.5 0.3 0.00019 21.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAJ10707.1 - 6e-05 22.2 0.2 0.00011 21.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 OAJ10707.1 - 8.4e-05 22.7 0.2 0.026 14.5 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ10707.1 - 0.00014 21.8 0.2 0.00041 20.2 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ10707.1 - 0.00036 19.6 2.5 0.00042 19.4 0.8 1.8 2 1 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 OAJ10707.1 - 0.001 18.8 0.6 0.38 10.5 0.1 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 OAJ10707.1 - 0.0024 16.8 0.1 1.3 7.8 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.2 OAJ10707.1 - 0.0081 15.2 2.2 0.012 14.6 1.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 OAJ10707.1 - 0.063 12.1 1.4 0.25 10.1 0.5 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Afi1 PF07792.7 OAJ10708.1 - 9.7 6.1 7.9 5.8 6.9 3.9 1.8 1 1 1 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Diphthamide_syn PF01866.12 OAJ10709.1 - 2.4e-73 247.0 0.0 8.2e-32 110.6 0.0 5.8 4 1 0 4 4 4 4 Putative diphthamide synthesis protein Lyase_aromatic PF00221.14 OAJ10713.1 - 2.4e-157 524.2 4.4 3e-157 523.8 3.1 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase DDE_3 PF13358.1 OAJ10714.1 - 1e-19 70.7 0.0 2.3e-19 69.6 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 OAJ10714.1 - 2.7e-17 62.5 7.2 8.5e-17 60.9 5.0 1.9 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 OAJ10714.1 - 5.5e-05 23.8 1.4 5.5e-05 23.8 0.9 3.2 2 2 1 3 3 3 1 Homeodomain-like domain rve PF00665.21 OAJ10714.1 - 0.0015 18.6 0.0 0.0057 16.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_21 PF13276.1 OAJ10714.1 - 0.0028 17.6 1.5 0.011 15.7 1.0 2.0 1 0 0 1 1 1 1 HTH-like domain DDE_Tnp_ISAZ013 PF07592.6 OAJ10714.1 - 0.0084 14.8 0.2 0.54 8.9 0.1 2.2 2 0 0 2 2 2 1 Rhodopirellula transposase DDE domain HTH_28 PF13518.1 OAJ10714.1 - 0.041 13.8 3.9 0.15 12.0 0.1 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain DUF668 PF05003.7 OAJ10714.1 - 0.081 13.1 0.3 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF668) GcrA PF07750.6 OAJ10714.1 - 0.23 11.6 3.2 0.41 10.8 2.2 1.4 1 0 0 1 1 1 0 GcrA cell cycle regulator HTH_38 PF13936.1 OAJ10714.1 - 1.8 8.1 5.8 6.8 6.3 0.0 3.6 3 1 1 4 4 4 0 Helix-turn-helix domain G-patch PF01585.18 OAJ10715.1 - 6.2e-14 51.5 0.7 6.2e-14 51.5 0.5 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 OAJ10715.1 - 0.00012 21.8 0.3 0.00012 21.8 0.2 3.8 4 1 0 4 4 4 1 DExH-box splicing factor binding site Daxx PF03344.10 OAJ10715.1 - 0.055 11.9 24.9 0.081 11.4 17.2 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 OAJ10715.1 - 0.54 8.2 16.2 0.017 13.2 3.2 2.1 2 0 0 2 2 2 0 CDC45-like protein GAGA_bind PF06217.7 OAJ10715.1 - 3 7.7 17.1 0.12 12.3 2.3 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family TATR PF03430.8 OAJ10715.1 - 5.4 5.5 17.6 0.18 10.3 2.1 2.1 2 0 0 2 2 2 0 Trans-activating transcriptional regulator rve PF00665.21 OAJ10724.1 - 2.3e-14 53.5 0.0 6.4e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ10724.1 - 6.3e-12 45.3 0.2 1.6e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 OAJ10724.1 - 8.3e-08 32.2 0.0 2.2e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ10724.1 - 2.1e-07 30.6 0.0 5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAJ10724.1 - 2.1e-06 28.1 0.0 4.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.19 OAJ10724.1 - 0.00014 21.4 0.7 0.00042 19.9 0.2 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 OAJ10724.1 - 0.00061 19.8 0.1 0.0026 17.7 0.1 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAJ10724.1 - 0.001 18.9 3.5 0.0027 17.5 2.4 1.8 1 0 0 1 1 1 1 Zinc knuckle Zn_clus PF00172.13 OAJ10727.1 - 2.8e-08 33.5 8.3 4.5e-08 32.8 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAJ10727.1 - 1.9e-06 26.9 0.0 7.4e-06 25.0 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain CENP-X PF09415.5 OAJ10727.1 - 7.5 6.4 5.6 1.8 8.4 0.3 2.5 3 0 0 3 3 3 0 CENP-S associating Centromere protein X HD_3 PF13023.1 OAJ10728.1 - 5.8e-38 130.2 0.0 1e-37 129.4 0.0 1.3 1 0 0 1 1 1 1 HD domain HD PF01966.17 OAJ10728.1 - 0.00014 21.8 0.1 0.00034 20.6 0.1 1.6 1 0 0 1 1 1 1 HD domain DUF2340 PF10209.4 OAJ10732.1 - 2.9e-42 143.6 0.0 4e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) PhyH PF05721.8 OAJ10733.1 - 8.8e-42 143.5 0.0 1.4e-41 142.8 0.0 1.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RRP7 PF12923.2 OAJ10734.1 - 2.9e-21 75.8 8.3 2.9e-21 75.8 5.8 3.0 2 1 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 OAJ10734.1 - 5.6e-05 22.7 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ10734.1 - 0.0017 18.2 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sec7 PF01369.15 OAJ10735.1 - 6.6e-37 127.0 0.0 1.5e-36 125.8 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 OAJ10735.1 - 1.2e-29 102.8 0.0 2.1e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 OAJ10735.1 - 0.00028 21.0 0.0 0.00055 20.1 0.0 1.4 1 0 0 1 1 1 1 PH domain Hemerythrin PF01814.18 OAJ10741.1 - 9.9e-11 41.9 4.8 1.6e-09 37.9 3.4 2.0 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain Sod_Fe_C PF02777.13 OAJ10742.1 - 1.4e-14 53.7 0.0 5e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 OAJ10742.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain BTB PF00651.26 OAJ10744.1 - 6.2e-07 29.3 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Methyltransf_23 PF13489.1 OAJ10750.1 - 8.6e-08 32.0 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ10750.1 - 1.3e-07 32.0 0.0 4.4e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ10750.1 - 2.4e-07 31.1 0.0 1.8e-06 28.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ10750.1 - 4.6e-05 23.4 0.0 0.00011 22.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 OAJ10750.1 - 0.00016 22.4 0.1 0.0022 18.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ10750.1 - 0.00073 19.1 0.0 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ10750.1 - 0.0019 18.4 0.0 0.0044 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 OAJ10750.1 - 0.0024 17.2 0.0 0.0086 15.5 0.0 1.8 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.2 OAJ10750.1 - 0.014 15.9 0.0 0.041 14.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ10750.1 - 0.074 12.1 0.0 0.15 11.1 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MFS_1 PF07690.11 OAJ10751.1 - 8.5e-29 100.3 13.3 8.5e-29 100.3 9.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAJ10751.1 - 2e-09 36.3 4.2 0.0015 17.0 0.0 3.2 2 2 1 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 OAJ10751.1 - 7.6e-07 28.0 8.2 1.4e-06 27.1 4.8 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 OAJ10751.1 - 0.0045 15.2 0.9 0.0069 14.6 0.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 OAJ10751.1 - 0.33 9.3 8.1 0.021 13.3 1.3 2.0 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like Chitin_bind_1 PF00187.14 OAJ10752.1 - 0.038 13.9 3.5 0.038 13.9 2.4 2.8 2 1 0 2 2 2 0 Chitin recognition protein ApbA_C PF08546.6 OAJ10753.1 - 1.1e-23 83.6 0.0 2.9e-23 82.2 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 OAJ10753.1 - 3.7e-19 68.6 0.0 5.8e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.19 OAJ10753.1 - 0.0031 16.4 0.2 0.0065 15.4 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 OAJ10753.1 - 0.0064 16.7 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 OAJ10753.1 - 0.038 13.5 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 OAJ10753.1 - 0.042 13.2 0.2 0.4 10.0 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 OAJ10753.1 - 0.053 13.3 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 ThiF family NAD_binding_10 PF13460.1 OAJ10753.1 - 0.068 13.1 0.0 0.27 11.2 0.0 2.1 3 0 0 3 3 3 0 NADH(P)-binding 3HCDH_N PF02737.13 OAJ10753.1 - 0.11 12.2 0.4 0.43 10.2 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 OAJ10753.1 - 0.13 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 OAJ10753.1 - 0.14 12.6 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FliD_N PF02465.13 OAJ10758.1 - 0.0048 17.2 0.3 0.015 15.6 0.2 1.7 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 N-terminus RVT_1 PF00078.22 OAJ10759.1 - 1.2e-17 64.0 0.0 2.5e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10759.1 - 6.2e-15 55.3 0.0 1.5e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 OAJ10759.1 - 0.14 11.9 0.0 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 DDE superfamily endonuclease Herpes_ORF11 PF04797.8 OAJ10759.1 - 0.28 9.5 0.0 0.42 8.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus dUTPase protein RNase_P_Rpp14 PF01900.14 OAJ10763.1 - 2.5e-24 85.2 0.0 3.3e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Cellulase PF00150.13 OAJ10764.1 - 9.6e-14 51.2 0.5 1.4e-13 50.6 0.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TPR_11 PF13414.1 OAJ10765.1 - 3e-11 42.7 6.2 2.5e-05 23.8 0.1 4.8 3 1 1 4 4 4 3 TPR repeat TPR_16 PF13432.1 OAJ10765.1 - 1.8e-10 41.2 29.4 0.00011 22.7 1.9 6.6 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ10765.1 - 9.4e-10 37.9 0.7 0.014 15.4 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ10765.1 - 2.2e-07 30.2 7.1 0.11 12.4 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ10765.1 - 9e-07 28.9 1.2 0.0087 16.1 0.0 4.5 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 OAJ10765.1 - 5.3e-06 26.5 22.8 0.031 14.8 0.4 7.5 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ10765.1 - 5.1e-05 23.5 17.1 0.14 12.5 0.1 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ10765.1 - 0.0003 20.2 2.7 1.7 8.4 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ10765.1 - 0.0043 16.7 0.1 3.3 7.7 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.5 OAJ10765.1 - 0.056 12.1 1.8 1.5 7.5 0.2 2.5 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.1 OAJ10765.1 - 1.5 8.7 8.3 4.2 7.4 0.0 4.6 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ10765.1 - 1.6 8.6 17.4 1.7 8.5 0.4 5.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ10765.1 - 2 8.3 26.6 0.5 10.3 0.4 6.8 8 1 1 9 9 8 0 Tetratricopeptide repeat Ubiq_cyt_C_chap PF03981.7 OAJ10772.1 - 0.15 11.9 0.2 0.28 11.0 0.0 1.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C chaperone DDE_Tnp_4 PF13359.1 OAJ10773.1 - 6.9e-27 93.9 0.0 1.1e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 OAJ10773.1 - 3.4e-05 23.4 0.3 0.0002 20.9 0.0 2.3 2 1 0 2 2 2 1 Transposase DDE domain Plant_tran PF04827.9 OAJ10773.1 - 0.00018 20.9 0.0 0.0023 17.3 0.0 2.1 2 0 0 2 2 2 1 Plant transposon protein Glyco_hydro_45 PF02015.11 OAJ10780.1 - 6.7e-49 166.6 7.7 8.9e-49 166.2 5.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 UBN2_3 PF14244.1 OAJ10781.1 - 2e-05 24.1 0.0 2.3e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Phospholip_A2_2 PF05826.7 OAJ10781.1 - 0.07 13.0 0.0 0.08 12.8 0.0 1.1 1 0 0 1 1 1 0 Phospholipase A2 Lipase_3 PF01764.20 OAJ10783.1 - 4.7e-20 71.6 0.0 7.1e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.8 OAJ10783.1 - 0.024 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ10783.1 - 0.069 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family gag_pre-integrs PF13976.1 OAJ10784.1 - 0.0066 16.0 0.1 0.016 14.8 0.0 1.6 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-CCHC PF00098.18 OAJ10784.1 - 0.026 14.4 3.2 0.026 14.4 2.2 1.8 2 0 0 2 2 2 0 Zinc knuckle RVP PF00077.15 OAJ10784.1 - 0.076 12.9 0.0 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease RVT_2 PF07727.9 OAJ10785.1 - 4.6e-59 199.3 0.0 2.3e-32 111.9 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) An_peroxidase PF03098.10 OAJ10796.1 - 1.3e-74 251.5 0.0 2.8e-72 243.8 0.0 2.3 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 OAJ10796.1 - 5.5e-14 51.5 0.0 9.4e-14 50.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 rve PF00665.21 OAJ10797.1 - 8.3e-17 61.4 0.0 5.7e-16 58.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Cation_ATPase_C PF00689.16 OAJ10798.1 - 3e-37 127.8 2.7 4.3e-37 127.4 1.8 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ10798.1 - 6.3e-22 79.0 0.0 1e-21 78.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAJ10798.1 - 8.5e-08 32.5 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2556 PF10831.3 OAJ10798.1 - 0.01 15.4 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2556) Hydrolase_3 PF08282.7 OAJ10798.1 - 0.096 12.2 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FHA PF00498.21 OAJ10806.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 FHA domain Transposase_21 PF02992.9 OAJ10807.1 - 2.5e-18 65.9 0.1 4.3e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Sulfate_tra_GLY PF13792.1 OAJ10813.1 - 2.7e-09 36.5 0.1 6.1e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif DDE_Tnp_4 PF13359.1 OAJ10819.1 - 5.8e-10 38.9 0.2 7.7e-10 38.5 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ10819.1 - 3e-05 23.4 0.0 4.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Nucleoside_tran PF01733.13 OAJ10819.1 - 0.069 12.2 0.0 0.095 11.8 0.0 1.1 1 0 0 1 1 1 0 Nucleoside transporter rve PF00665.21 OAJ10820.1 - 1.4e-19 70.3 0.0 4.9e-19 68.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ10820.1 - 1.8e-16 60.1 0.0 4e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Omp28 PF11551.3 OAJ10820.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Outer membrane protein Omp28 Myb_DNA-bind_3 PF12776.2 OAJ10821.1 - 0.0056 17.2 0.1 0.012 16.1 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Pox_T4_N PF04491.7 OAJ10821.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus Phage_integrase PF00589.17 OAJ10828.1 - 7.5e-18 64.7 0.1 8.6e-18 64.5 0.1 1.1 1 0 0 1 1 1 1 Phage integrase family DUF4608 PF15381.1 OAJ10828.1 - 0.062 13.4 0.0 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4608) TctB PF07331.6 OAJ10829.1 - 0.029 14.0 0.2 0.031 13.9 0.1 1.2 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF2976 PF11190.3 OAJ10829.1 - 0.21 11.1 1.4 0.24 10.9 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) NAC PF01849.13 OAJ10837.1 - 1.7e-18 65.9 0.0 2.9e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 NAC domain Glyco_hydro_15 PF00723.16 OAJ10838.1 - 1.1e-79 268.0 0.1 1.5e-79 267.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Pkinase PF00069.20 OAJ10839.1 - 3.7e-72 242.5 0.0 4.5e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ10839.1 - 7.2e-31 107.2 0.0 8.8e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ10839.1 - 0.00055 19.7 0.0 0.00088 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ10839.1 - 0.001 18.2 0.0 0.0031 16.6 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ10839.1 - 0.0039 16.1 0.0 0.029 13.3 0.0 2.0 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 OAJ10839.1 - 0.05 12.9 0.1 0.1 11.9 0.0 1.5 2 0 0 2 2 2 0 RIO1 family ORC3_N PF07034.6 OAJ10846.1 - 4.2e-17 62.1 0.1 1.6e-16 60.2 0.1 2.0 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus F-box-like PF12937.2 OAJ10847.1 - 0.00025 20.6 0.3 0.00076 19.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 OAJ10847.1 - 0.029 14.3 2.4 31 5.1 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 OAJ10847.1 - 0.18 12.1 5.6 17 6.2 0.0 4.4 4 0 0 4 4 4 0 Leucine rich repeat LRR_8 PF13855.1 OAJ10847.1 - 2.9 7.7 3.4 22 4.9 0.3 3.2 3 1 0 3 3 3 0 Leucine rich repeat DDE_1 PF03184.14 OAJ10851.1 - 1e-33 116.3 0.0 1.2e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 OAJ10851.1 - 0.061 13.0 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Retrotrans_gag PF03732.12 OAJ10853.1 - 5.7e-11 42.3 0.6 5.5e-10 39.1 0.4 2.2 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAJ10853.1 - 0.00053 19.7 0.6 0.00083 19.1 0.4 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF4473 PF14747.1 OAJ10853.1 - 0.0073 16.4 0.0 0.024 14.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4473) rve PF00665.21 OAJ10854.1 - 3.5e-23 81.9 0.0 7.3e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ10854.1 - 3.5e-14 52.6 0.0 8.3e-14 51.4 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 OAJ10854.1 - 4.1e-08 32.7 0.1 7.8e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.6 OAJ10854.1 - 4.4e-07 29.9 0.0 6.8e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAJ10854.1 - 0.00045 20.6 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.1 OAJ10854.1 - 0.0048 16.3 0.1 0.015 14.8 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain LANC_like PF05147.8 OAJ10854.1 - 0.54 8.7 0.0 0.84 8.1 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein ZZ PF00569.12 OAJ10860.1 - 2.3e-22 78.2 61.8 1.1e-07 31.2 1.7 5.9 6 0 0 6 6 6 4 Zinc finger, ZZ type PPR_2 PF13041.1 OAJ10861.1 - 0.0011 18.8 0.0 0.047 13.6 0.0 2.7 3 0 0 3 3 3 1 PPR repeat family DUF3464 PF11947.3 OAJ10861.1 - 0.071 12.5 0.8 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) TMEM171 PF15471.1 OAJ10861.1 - 1.4 7.6 5.8 8.6 5.0 0.1 3.0 3 0 0 3 3 3 0 Transmembrane protein family 171 Nop PF01798.13 OAJ10862.1 - 3.1e-58 195.3 0.2 6.4e-58 194.3 0.1 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 OAJ10862.1 - 1.6e-25 88.6 1.0 2.3e-25 88.1 0.1 1.8 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 OAJ10862.1 - 5e-18 65.0 0.0 5e-18 65.0 0.0 3.0 3 1 0 3 3 3 1 NOP5NT (NUC127) domain Sporozoite_P67 PF05642.6 OAJ10862.1 - 0.02 12.7 12.1 0.029 12.2 8.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BCDHK_Adom3 PF10436.4 OAJ10862.1 - 0.024 14.1 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase CDC45 PF02724.9 OAJ10862.1 - 1.3 6.9 26.2 2 6.3 18.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.4 OAJ10862.1 - 3.5 6.3 26.2 5.7 5.6 18.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DDHD PF02862.12 OAJ10862.1 - 8.5 6.1 13.0 21 4.7 9.0 1.8 1 0 0 1 1 1 0 DDHD domain AAA PF00004.24 OAJ10869.1 - 3.9e-44 150.0 0.0 6.8e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 OAJ10869.1 - 2.3e-08 34.1 0.0 4.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 OAJ10869.1 - 1.1e-06 28.3 0.0 5.8e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 OAJ10869.1 - 2e-06 28.0 0.2 0.00031 20.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ10869.1 - 2.1e-06 27.8 0.1 1.5e-05 25.0 0.0 2.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 OAJ10869.1 - 6.4e-05 22.6 0.0 0.00018 21.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 OAJ10869.1 - 7.2e-05 23.5 0.0 0.00018 22.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAJ10869.1 - 8.3e-05 21.7 0.0 0.00017 20.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 OAJ10869.1 - 0.00042 19.7 0.0 0.00088 18.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 OAJ10869.1 - 0.00098 17.9 0.0 0.002 16.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 OAJ10869.1 - 0.0013 18.5 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ10869.1 - 0.0015 18.4 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAJ10869.1 - 0.0025 16.9 0.0 0.0048 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.1 OAJ10869.1 - 0.0029 17.2 0.0 0.046 13.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 OAJ10869.1 - 0.0037 17.2 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 OAJ10869.1 - 0.0039 16.8 0.0 0.0082 15.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 OAJ10869.1 - 0.0041 16.3 0.0 0.068 12.3 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 OAJ10869.1 - 0.0069 15.5 0.1 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 OAJ10869.1 - 0.0075 16.5 0.0 0.028 14.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain DUF2072 PF09845.4 OAJ10869.1 - 0.014 15.3 0.1 0.027 14.3 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) KaiC PF06745.8 OAJ10869.1 - 0.015 14.3 0.0 0.035 13.2 0.0 1.6 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 OAJ10869.1 - 0.018 14.5 0.0 0.096 12.1 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_25 PF13481.1 OAJ10869.1 - 0.021 14.2 0.1 0.09 12.1 0.0 1.9 1 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 OAJ10869.1 - 0.027 13.4 0.0 0.052 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 OAJ10869.1 - 0.036 14.2 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 OAJ10869.1 - 0.042 13.4 0.0 0.59 9.7 0.0 2.2 1 1 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 OAJ10869.1 - 0.054 13.5 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 OAJ10869.1 - 0.056 12.3 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 OAJ10869.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Amidase PF01425.16 OAJ10870.1 - 2.6e-78 263.8 0.1 1.5e-64 218.5 0.1 2.0 2 0 0 2 2 2 2 Amidase Aa_trans PF01490.13 OAJ10871.1 - 3.7e-57 193.6 8.3 1.7e-56 191.5 5.8 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 OAJ10871.1 - 0.00085 18.2 6.0 0.00085 18.2 4.2 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Nop14 PF04147.7 OAJ10871.1 - 2.9 5.6 9.3 4 5.2 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 OAJ10871.1 - 4.3 6.2 14.4 7.3 5.5 10.0 1.3 1 0 0 1 1 1 0 BUD22 PIF1 PF05970.9 OAJ10885.1 - 3e-106 355.4 0.0 3.9e-106 355.0 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ10885.1 - 1.3e-58 197.7 0.0 2.6e-58 196.7 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 OAJ10885.1 - 2.7e-06 27.1 0.0 4.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 OAJ10885.1 - 5.3e-05 21.1 0.0 0.00011 20.1 0.0 1.4 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 OAJ10885.1 - 0.0026 17.8 0.0 0.0063 16.6 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain T2SE PF00437.15 OAJ10885.1 - 0.017 13.9 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 OAJ10885.1 - 0.037 13.7 0.1 0.1 12.3 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain TrwB_AAD_bind PF10412.4 OAJ10885.1 - 0.039 12.5 0.0 0.17 10.4 0.0 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.7 OAJ10885.1 - 0.077 12.0 0.0 0.22 10.5 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.4 OAJ10885.1 - 0.081 11.8 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Glyco_hydro_43 PF04616.9 OAJ10894.1 - 1e-34 119.9 0.3 1.2e-34 119.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 HeH PF12949.2 OAJ10901.1 - 0.0023 17.4 0.1 0.0048 16.4 0.1 1.6 1 0 0 1 1 1 1 HeH/LEM domain ADIP PF11559.3 OAJ10902.1 - 0.23 11.3 2.7 0.19 11.5 0.7 1.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding OEP PF02321.13 OAJ10902.1 - 0.4 10.2 6.9 0.63 9.6 4.8 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein CHDCT2 PF08074.6 OAJ10902.1 - 0.59 9.8 3.3 0.36 10.5 1.1 1.5 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain HlyD PF00529.15 OAJ10902.1 - 3.1 7.0 11.0 4.3 6.5 7.6 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Collagen PF01391.13 OAJ10911.1 - 4.9e-06 25.9 15.9 7.4e-06 25.4 11.0 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) ICMT PF04140.9 OAJ10912.1 - 7.2e-14 51.7 0.4 2.8e-13 49.8 0.3 1.8 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 OAJ10912.1 - 5.1e-07 29.7 0.8 2.8e-06 27.3 0.6 1.9 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 OAJ10912.1 - 0.086 11.3 0.0 4.7 5.6 0.0 2.1 2 0 0 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family Dimer_Tnp_hAT PF05699.9 OAJ10919.1 - 3.3e-12 45.8 0.1 9.7e-12 44.3 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 OAJ10919.1 - 0.0065 16.1 2.2 0.026 14.2 0.6 2.4 2 0 0 2 2 2 1 BED zinc finger Pkinase PF00069.20 OAJ10920.1 - 1.1e-42 146.0 0.0 1.4e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ10920.1 - 6.9e-20 71.2 0.0 1.1e-19 70.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ10920.1 - 3.3e-07 29.5 0.0 1.1e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAJ10920.1 - 0.00013 21.8 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 OAJ10920.1 - 0.0043 16.4 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 OAJ10920.1 - 0.022 13.8 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 OAJ10920.1 - 0.025 14.1 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase WaaY PF06176.6 OAJ10920.1 - 0.076 12.2 0.1 0.13 11.4 0.0 1.4 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) RVT_2 PF07727.9 OAJ10921.1 - 1.2e-76 256.9 0.0 1.7e-76 256.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ10921.1 - 1.3e-16 60.7 0.1 7.5e-16 58.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ10921.1 - 0.00086 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ10921.1 - 0.15 11.5 0.0 0.44 10.0 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain UBN2_2 PF14227.1 OAJ10922.1 - 3.7e-11 42.6 0.3 5.6e-11 42.0 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ10922.1 - 3.2e-10 39.8 1.1 4.9e-10 39.2 0.8 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 OAJ10922.1 - 2.3e-07 30.4 0.0 6.5e-07 29.0 0.0 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF572 PF04502.8 OAJ10922.1 - 0.036 13.2 0.4 0.049 12.8 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-CCHC PF00098.18 OAJ10922.1 - 2.1 8.3 9.7 0.1 12.5 2.8 1.8 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_L18ae PF01775.12 OAJ10931.1 - 2.6e-57 192.0 0.3 3.1e-57 191.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain DUF2883 PF11097.3 OAJ10931.1 - 0.054 13.6 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2883) ubiquitin PF00240.18 OAJ10932.1 - 1.3e-34 117.3 1.1 1.7e-34 116.9 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 OAJ10932.1 - 1.1e-29 101.7 8.3 1.7e-29 101.1 5.8 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 OAJ10932.1 - 6.4e-20 70.6 0.8 8.5e-20 70.2 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAJ10932.1 - 7.3e-06 26.1 0.2 2.7e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAJ10932.1 - 0.00016 21.3 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 OAJ10932.1 - 0.0077 16.1 0.1 0.015 15.1 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 OAJ10932.1 - 0.011 15.9 0.1 0.014 15.6 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain zf-DHHC PF01529.15 OAJ10932.1 - 0.3 10.4 2.6 0.45 9.8 1.8 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Pkinase PF00069.20 OAJ10933.1 - 1e-36 126.4 0.0 6.2e-11 41.9 0.0 4.2 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ10933.1 - 5.4e-15 55.1 0.0 3.7e-08 32.7 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase F-box PF00646.28 OAJ10933.1 - 0.026 14.1 2.4 0.072 12.7 1.7 1.7 1 0 0 1 1 1 0 F-box domain PDT PF00800.13 OAJ10934.1 - 2.6e-42 144.4 0.0 9.7e-36 123.0 0.0 2.9 2 1 0 2 2 2 2 Prephenate dehydratase Pkinase PF00069.20 OAJ10944.1 - 3.8e-40 137.6 0.0 6e-40 137.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ10944.1 - 1.1e-23 83.5 0.0 1.6e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Dimer_Tnp_hAT PF05699.9 OAJ10946.1 - 1.9e-12 46.6 0.0 3.4e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TFIID_20kDa PF03847.8 OAJ10953.1 - 7.9e-32 109.3 0.3 1.2e-31 108.7 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 OAJ10953.1 - 0.0084 16.1 0.1 0.019 15.0 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Occludin_ELL PF07303.8 OAJ10953.1 - 0.051 14.3 0.2 0.051 14.3 0.1 2.3 2 0 0 2 2 2 0 Occludin homology domain R3H-assoc PF13902.1 OAJ10953.1 - 0.29 11.1 2.5 7.7 6.4 0.0 3.3 3 1 1 4 4 4 0 R3H-associated N-terminal domain DUF4413 PF14372.1 OAJ10961.1 - 0.00071 19.5 0.0 0.0031 17.4 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) CHRD PF07452.7 OAJ10971.1 - 2.7e-16 60.2 0.0 4.3e-07 30.5 0.0 2.9 2 2 0 2 2 2 2 CHRD domain Acetyltransf_3 PF13302.1 OAJ10972.1 - 1.2e-08 35.2 0.0 1.4e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Lactonase PF10282.4 OAJ10974.1 - 1.2e-17 64.0 0.0 3.8e-17 62.3 0.0 1.8 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Eno-Rase_NADH_b PF12242.3 OAJ10974.1 - 0.12 12.1 0.0 0.68 9.7 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Chorion_S16 PF05836.7 OAJ10981.1 - 0.068 13.0 0.4 0.26 11.2 0.1 1.9 2 0 0 2 2 2 0 Chorion protein S16 GCR1_C PF12550.3 OAJ10982.1 - 1.1e-19 70.1 0.5 2.1e-19 69.1 0.3 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Glyco_hydro_17 PF00332.13 OAJ10982.1 - 0.0085 15.1 0.1 0.016 14.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Mid1 PF12929.2 OAJ10983.1 - 1.3e-59 201.9 0.0 2e-59 201.4 0.0 1.2 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component rve PF00665.21 OAJ10991.1 - 3.1e-19 69.2 0.0 7.8e-19 67.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ10991.1 - 1e-16 60.9 0.0 2.9e-16 59.4 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 OAJ10991.1 - 0.00065 19.1 0.1 0.0042 16.5 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Dimer_Tnp_hAT PF05699.9 OAJ10992.1 - 1.5e-23 82.2 0.1 4.9e-23 80.5 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 OAJ10992.1 - 1.2e-06 28.1 2.5 2.5e-06 27.1 1.7 1.6 1 0 0 1 1 1 1 BED zinc finger DUF59 PF01883.14 OAJ10992.1 - 0.026 14.5 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF59 SH3_9 PF14604.1 OAJ11000.1 - 3.8e-15 55.2 1.4 7.8e-15 54.2 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain Cofilin_ADF PF00241.15 OAJ11000.1 - 6.6e-14 51.8 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.23 OAJ11000.1 - 4.4e-13 48.4 1.4 7.4e-13 47.6 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 OAJ11000.1 - 2.7e-09 36.3 0.2 3.3e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Mob1_phocein PF03637.12 OAJ11002.1 - 1e-21 77.4 0.0 1.5e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family Vfa1 PF08432.5 OAJ11002.1 - 0.03 14.3 0.2 0.046 13.7 0.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 W2 PF02020.13 OAJ11003.1 - 1.4e-09 37.7 0.0 1.4e-09 37.7 0.0 4.5 4 1 0 4 4 4 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 OAJ11003.1 - 4.1e-08 32.3 1.2 0.0001 21.6 0.1 3.6 1 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 OAJ11003.1 - 0.00012 21.4 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 OAJ11003.1 - 0.0004 19.8 3.2 0.0036 16.8 2.3 2.4 1 1 1 2 2 2 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 OAJ11003.1 - 0.0045 15.6 0.3 0.0076 14.8 0.2 1.3 1 0 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.2 OAJ11003.1 - 0.019 15.0 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain Sec15 PF04091.7 OAJ11012.1 - 3.8e-72 243.2 0.0 6e-71 239.3 0.0 2.4 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.9 OAJ11012.1 - 4.5e-05 23.1 0.2 4.5e-05 23.1 0.1 3.0 4 0 0 4 4 4 1 Sec8 exocyst complex component specific domain Sec5 PF15469.1 OAJ11012.1 - 0.00036 20.2 0.7 0.0015 18.3 0.2 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 COG5 PF10392.4 OAJ11012.1 - 0.0022 17.9 3.4 0.013 15.4 0.0 3.3 3 1 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.6 OAJ11012.1 - 0.0047 16.7 0.1 0.039 13.8 0.0 2.7 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 OAJ11012.1 - 0.072 12.9 3.6 0.11 12.4 0.4 2.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DDE_Tnp_4 PF13359.1 OAJ11014.1 - 4.5e-30 104.3 0.0 6.3e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ11014.1 - 7.2e-08 32.0 0.0 7.7e-07 28.6 0.0 2.1 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 OAJ11014.1 - 0.00032 20.8 1.1 0.00078 19.5 0.1 2.0 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.16 OAJ11014.1 - 0.001 18.6 0.0 0.0029 17.1 0.0 1.7 1 1 0 1 1 1 1 Transposase DDE domain Myb_DNA-bind_3 PF12776.2 OAJ11015.1 - 7.4e-16 58.5 0.0 1.2e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ11015.1 - 3.5e-06 27.0 0.5 0.00012 22.1 0.0 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain CAF-1_p150 PF11600.3 OAJ11015.1 - 0.88 8.8 8.1 0.078 12.3 0.6 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Abhydrolase_6 PF12697.2 OAJ11022.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family NAD_binding_10 PF13460.1 OAJ11023.1 - 0.00049 20.1 0.3 0.016 15.2 0.2 2.7 1 1 0 1 1 1 1 NADH(P)-binding WD40 PF00400.27 OAJ11024.1 - 2.3e-10 39.9 8.6 4e-05 23.3 0.0 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF3106 PF11304.3 OAJ11032.1 - 0.0044 17.4 6.0 0.0058 17.0 0.6 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3106) Dimer_Tnp_hAT PF05699.9 OAJ11033.1 - 4e-16 58.4 0.0 8.9e-16 57.2 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DBD_Tnp_Hermes PF10683.4 OAJ11033.1 - 0.0022 17.4 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 Hermes transposase DNA-binding domain DUF4413 PF14372.1 OAJ11033.1 - 0.24 11.3 0.0 0.51 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Pkinase PF00069.20 OAJ11035.1 - 4e-50 170.3 0.0 5.6e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ11035.1 - 1.9e-29 102.5 0.0 3.7e-29 101.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase AAA_27 PF13514.1 OAJ11035.1 - 0.0053 14.5 7.0 0.0075 14.0 4.8 1.1 1 0 0 1 1 1 1 AAA domain Kdo PF06293.9 OAJ11035.1 - 0.021 13.8 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IncA PF04156.9 OAJ11035.1 - 0.028 14.0 0.6 0.05 13.1 0.4 1.4 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 OAJ11035.1 - 0.08 12.1 1.2 0.13 11.3 0.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Kinase-like PF14531.1 OAJ11035.1 - 0.088 11.7 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Allexi_40kDa PF05549.6 OAJ11035.1 - 0.15 11.3 1.0 0.56 9.4 0.3 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein CENP-F_leu_zip PF10473.4 OAJ11035.1 - 0.49 10.2 4.1 0.58 10.0 1.6 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4140 PF13600.1 OAJ11035.1 - 0.52 10.7 4.0 4.5 7.7 1.6 3.0 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 OAJ11035.1 - 2.9 7.4 6.7 3.1 7.3 0.2 2.6 2 1 1 3 3 3 0 Septum formation initiator BMFP PF04380.8 OAJ11035.1 - 9.1 6.5 7.8 11 6.2 1.1 3.2 3 0 0 3 3 3 0 Membrane fusogenic activity COesterase PF00135.23 OAJ11043.1 - 4.2e-44 151.1 2.0 1e-42 146.6 1.4 2.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ11043.1 - 1.7e-06 27.7 0.0 3.9e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ11043.1 - 0.0069 16.1 0.1 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ11043.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family ATP_bind_1 PF03029.12 OAJ11044.1 - 1.1e-72 244.4 0.0 1.3e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 OAJ11044.1 - 4.1e-05 24.3 0.0 0.00011 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 OAJ11044.1 - 0.0054 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_19 PF13245.1 OAJ11044.1 - 0.015 14.9 0.0 0.048 13.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 OAJ11044.1 - 0.039 13.8 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 OAJ11044.1 - 0.04 13.8 0.6 0.26 11.2 0.4 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 OAJ11044.1 - 0.058 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 OAJ11044.1 - 0.061 12.7 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 OAJ11044.1 - 0.07 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 ArgK protein SRP54 PF00448.17 OAJ11044.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RibD_C PF01872.12 OAJ11055.1 - 5.6e-34 117.5 0.0 1.7e-33 115.9 0.0 1.8 2 0 0 2 2 2 1 RibD C-terminal domain Sec7 PF01369.15 OAJ11055.1 - 1.5e-29 103.0 0.0 2.3e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain His_biosynth PF00977.16 OAJ11056.1 - 4.6e-35 120.9 0.0 6e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 OAJ11056.1 - 0.0074 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PcrB PF01884.12 OAJ11056.1 - 0.088 12.0 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 PcrB family Phage_Gp23 PF10669.4 OAJ11056.1 - 0.44 10.6 0.1 0.44 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Prp19 PF08606.6 OAJ11057.1 - 3.2e-28 97.2 0.9 6.4e-28 96.2 0.6 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 OAJ11057.1 - 1.6e-24 84.7 2.5 2.6e-08 33.4 0.0 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat U-box PF04564.10 OAJ11057.1 - 0.00081 19.3 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 U-box domain Rtf2 PF04641.7 OAJ11057.1 - 0.0028 16.8 0.1 0.0072 15.5 0.0 1.7 2 0 0 2 2 2 1 Rtf2 RING-finger zf-Nse PF11789.3 OAJ11057.1 - 0.0057 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit ADH_zinc_N_2 PF13602.1 OAJ11058.1 - 1.1e-16 61.8 0.0 2.3e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 OAJ11058.1 - 1.5e-14 53.6 0.0 2.9e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DeoRC PF00455.17 OAJ11058.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 DeoR C terminal sensor domain ADH_N PF08240.7 OAJ11058.1 - 0.02 14.6 0.0 0.089 12.5 0.0 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain Phage_integrase PF00589.17 OAJ11064.1 - 9.2e-05 22.1 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 OAJ11064.1 - 0.15 12.2 0.0 1.7 8.8 0.0 2.2 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain PSRT PF07636.6 OAJ11065.1 - 0.38 10.2 6.2 0.95 8.9 4.3 1.7 1 0 0 1 1 1 0 PSRT gag-asp_proteas PF13975.1 OAJ11066.1 - 1.6e-09 37.4 0.0 3.5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAJ11066.1 - 1.9e-06 28.2 0.0 3.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ11066.1 - 0.023 14.6 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease K_channel_TID PF07941.6 OAJ11071.1 - 0.14 12.4 10.0 0.68 10.2 5.3 2.6 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain GCR1_C PF12550.3 OAJ11085.1 - 0.033 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes DUF3947 PF13135.1 OAJ11085.1 - 1.1 9.5 4.9 1.9 8.7 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) HTH_23 PF13384.1 OAJ11086.1 - 0.013 15.1 0.0 0.14 11.8 0.0 2.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_1 PF01527.15 OAJ11086.1 - 0.032 14.1 0.1 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Transposase HTH_29 PF13551.1 OAJ11086.1 - 0.056 13.5 0.1 1.4 9.0 0.0 2.7 2 0 0 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.1 OAJ11086.1 - 0.16 12.0 2.3 0.35 10.8 0.0 2.8 4 0 0 4 4 4 0 Helix-turn-helix domain G-patch PF01585.18 OAJ11091.1 - 2.9e-11 42.9 5.6 4.2e-11 42.4 0.9 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 OAJ11091.1 - 0.00012 21.8 1.2 0.00019 21.2 0.8 1.5 1 1 0 1 1 1 1 DExH-box splicing factor binding site DUF3661 PF12400.3 OAJ11093.1 - 2.9e-39 134.1 5.8 4.1e-39 133.6 4.1 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein DAP3 PF10236.4 OAJ11094.1 - 1.9e-38 132.1 0.0 4.4e-38 130.9 0.0 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 OAJ11094.1 - 0.00077 19.4 4.2 0.0018 18.3 2.9 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ11094.1 - 0.018 15.1 0.0 1 9.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAJ11094.1 - 0.022 14.5 0.1 0.079 12.7 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain GTP1_OBG PF01018.17 OAJ11095.1 - 4e-38 130.5 3.5 8e-28 97.0 0.5 3.0 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.18 OAJ11095.1 - 2.9e-17 62.7 0.0 7.8e-17 61.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ11095.1 - 0.00042 19.6 0.1 0.00083 18.6 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 OAJ11095.1 - 0.018 14.4 0.0 3.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ArgK PF03308.11 OAJ11095.1 - 0.13 11.0 0.7 0.83 8.3 0.1 2.2 2 0 0 2 2 2 0 ArgK protein ABC_tran PF00005.22 OAJ11095.1 - 0.42 10.9 0.1 0.42 10.9 0.0 2.3 3 0 0 3 3 3 0 ABC transporter Dynamin_N PF00350.18 OAJ11095.1 - 0.46 10.2 3.7 0.54 10.0 0.1 2.7 2 1 0 2 2 2 0 Dynamin family DDE_3 PF13358.1 OAJ11101.1 - 4.5e-16 58.9 0.0 7e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAJ11101.1 - 1.7e-05 25.4 0.1 5.1e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 OAJ11101.1 - 6.3e-05 23.0 0.1 0.00016 21.8 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 OAJ11101.1 - 0.00021 21.3 0.2 0.00054 19.9 0.1 1.7 1 0 0 1 1 1 1 Transposase DDE_1 PF03184.14 OAJ11101.1 - 0.0031 16.6 0.0 0.0059 15.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 OAJ11101.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix DDHD PF02862.12 OAJ11108.1 - 2.9e-28 99.2 0.0 2.9e-28 99.2 0.0 3.8 3 2 0 3 3 3 2 DDHD domain PAS_9 PF13426.1 OAJ11110.1 - 1.8e-19 70.0 0.0 5.4e-18 65.2 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 OAJ11110.1 - 3.9e-07 29.8 0.0 1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 OAJ11110.1 - 1.9e-06 27.8 0.0 0.00012 22.0 0.0 2.8 2 0 0 2 2 2 1 PAS fold RGS PF00615.14 OAJ11110.1 - 4.8e-05 23.4 0.1 0.00012 22.1 0.0 1.7 2 0 0 2 2 2 1 Regulator of G protein signaling domain PAS_3 PF08447.6 OAJ11110.1 - 0.056 13.5 0.0 0.37 10.9 0.0 2.3 2 0 0 2 2 2 0 PAS fold Glyco_transf_21 PF13506.1 OAJ11117.1 - 2.7e-22 78.8 0.0 4.6e-09 35.8 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 OAJ11117.1 - 6.8e-15 55.4 0.0 3e-13 50.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 OAJ11117.1 - 0.0083 15.8 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 PROCN PF08083.6 OAJ11117.1 - 0.087 11.2 0.1 0.13 10.6 0.1 1.2 1 0 0 1 1 1 0 PROCN (NUC071) domain SPC22 PF04573.7 OAJ11118.1 - 4.8e-44 149.6 0.2 5.4e-44 149.5 0.1 1.0 1 0 0 1 1 1 1 Signal peptidase subunit APG6 PF04111.7 OAJ11119.1 - 4.3e-103 344.6 0.4 5.8e-103 344.2 0.2 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF972 PF06156.8 OAJ11119.1 - 0.0051 17.1 1.1 0.0051 17.1 0.7 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF972) HAUS-augmin3 PF14932.1 OAJ11119.1 - 0.02 14.0 11.0 0.04 13.0 7.6 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 IncA PF04156.9 OAJ11119.1 - 0.037 13.6 13.6 0.092 12.3 9.5 1.6 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 OAJ11119.1 - 0.049 11.4 4.6 0.071 10.9 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 OAJ11119.1 - 0.069 12.7 6.7 0.13 11.7 4.7 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 OAJ11119.1 - 1.7 7.5 6.9 3.4 6.5 4.8 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Rab5-bind PF09311.6 OAJ11119.1 - 4.7 7.0 19.5 6.1 6.6 0.2 2.4 2 0 0 2 2 2 0 Rabaptin-like protein IMS PF00817.15 OAJ11120.1 - 6.9e-44 149.2 0.2 1.2e-43 148.4 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 OAJ11120.1 - 3.1e-16 59.4 0.5 7.1e-16 58.2 0.3 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 OAJ11120.1 - 0.00061 19.6 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif PRA1 PF03208.14 OAJ11121.1 - 1.7e-39 134.6 0.3 2.1e-39 134.3 0.2 1.0 1 0 0 1 1 1 1 PRA1 family protein FA_desaturase PF00487.19 OAJ11121.1 - 4.5 6.6 7.6 60 2.9 5.3 2.0 1 1 0 1 1 1 0 Fatty acid desaturase GCR1_C PF12550.3 OAJ11129.1 - 2.6e-05 23.9 0.0 6.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_Tnp_1_2 PF13022.1 OAJ11129.1 - 0.027 14.2 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_23 PF13384.1 OAJ11129.1 - 0.029 14.0 0.1 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain Phage_integrase PF00589.17 OAJ11129.1 - 0.12 12.0 0.0 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 Phage integrase family Tho2 PF11262.3 OAJ11139.1 - 1.9e-56 191.3 0.1 1.9e-56 191.3 0.1 2.8 2 1 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 OAJ11139.1 - 5e-21 74.2 0.1 1.2e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit DUF1777 PF08648.7 OAJ11139.1 - 5.9e-05 22.8 30.7 5.9e-05 22.8 21.3 8.5 7 2 1 8 8 8 1 Protein of unknown function (DUF1777) RNase_H2-Ydr279 PF09468.5 OAJ11139.1 - 1.2 8.2 5.3 0.81 8.8 1.2 2.5 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) RRM_1 PF00076.17 OAJ11140.1 - 1.4e-32 111.1 1.0 3.8e-20 71.2 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ11140.1 - 7e-25 86.8 0.1 1.4e-14 53.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ11140.1 - 4e-10 39.3 0.0 1.7e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 OAJ11140.1 - 0.00058 19.5 0.0 0.32 10.7 0.0 2.4 2 0 0 2 2 2 2 Limkain b1 Calcipressin PF04847.7 OAJ11140.1 - 0.021 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Calcipressin DUF221 PF02714.10 OAJ11140.1 - 0.24 10.2 0.0 0.32 9.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF221 Grp1_Fun34_YaaH PF01184.14 OAJ11149.1 - 1.3e-39 135.6 6.3 1.7e-39 135.2 4.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family IncA PF04156.9 OAJ11149.1 - 0.089 12.3 0.6 0.089 12.3 0.4 1.9 2 1 0 2 2 2 0 IncA protein Aminotran_5 PF00266.14 OAJ11150.1 - 7.6e-90 301.3 0.0 1.1e-89 300.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MR_MLE_C PF13378.1 OAJ11150.1 - 0.016 15.1 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Enolase C-terminal domain-like DASH_Hsk3 PF08227.6 OAJ11151.1 - 1.7e-05 24.9 1.7 2.4e-05 24.4 1.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like SHQ1 PF04925.10 OAJ11152.1 - 6e-25 87.7 0.0 1.3e-14 54.0 0.0 2.2 2 0 0 2 2 2 2 SHQ1 protein YuzL PF14115.1 OAJ11152.1 - 0.63 10.3 3.3 2.4 8.5 2.3 1.9 1 0 0 1 1 1 0 YuzL-like protein Cys_Met_Meta_PP PF01053.15 OAJ11153.1 - 6e-95 317.7 0.0 6.8e-95 317.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 OAJ11153.1 - 5.4e-12 45.4 0.2 7.9e-12 44.8 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 OAJ11153.1 - 1.6e-10 40.4 0.1 2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 OAJ11153.1 - 2.2e-09 36.5 0.2 2.8e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 OAJ11153.1 - 3.1e-05 22.4 0.0 4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 OAJ11153.1 - 4.8e-05 22.6 0.1 0.00014 21.0 0.1 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 OAJ11153.1 - 0.12 11.0 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein SLA_LP_auto_ag PF05889.8 OAJ11153.1 - 0.19 10.1 0.1 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Fib_alpha PF08702.5 OAJ11162.1 - 0.022 14.8 2.7 0.045 13.8 0.0 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4481 PF14800.1 OAJ11162.1 - 0.13 11.1 0.6 0.58 9.0 0.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4481) Sigma70_ner PF04546.8 OAJ11162.1 - 0.3 10.6 7.6 0.092 12.3 2.9 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF3348 PF11828.3 OAJ11163.1 - 0.012 14.9 0.6 0.027 13.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3348) Apolipoprotein PF01442.13 OAJ11163.1 - 0.023 14.2 1.2 0.059 12.8 0.8 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2316 PF10078.4 OAJ11163.1 - 0.043 13.8 0.6 3.7 7.6 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) COG5 PF10392.4 OAJ11163.1 - 0.088 12.7 0.1 4.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 UBN2_2 PF14227.1 OAJ11165.1 - 2.3e-08 33.6 0.1 4e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ11165.1 - 0.0004 20.1 0.1 0.00074 19.2 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ11165.1 - 0.0011 18.8 11.3 0.0055 16.5 0.8 2.8 2 1 0 2 2 2 2 Zinc knuckle DUF4218 PF13960.1 OAJ11175.1 - 0.0034 16.8 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) BAAT_C PF08840.6 OAJ11176.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Atg14 PF10186.4 OAJ11178.1 - 0.0027 16.7 17.3 0.029 13.3 3.0 2.2 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 OAJ11178.1 - 2.4 6.4 7.5 0.35 9.2 0.8 2.1 2 0 0 2 2 2 0 AAA domain DUF4554 PF15091.1 OAJ11178.1 - 6.1 5.4 8.2 0.77 8.4 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4554) Occludin_ELL PF07303.8 OAJ11178.1 - 6.3 7.5 10.1 0.18 12.5 0.5 3.0 3 0 0 3 3 3 0 Occludin homology domain NPV_P10 PF05531.7 OAJ11178.1 - 6.3 7.1 6.3 1.2 9.4 0.5 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF607 PF04678.8 OAJ11178.1 - 9.8 6.0 9.3 4.6 7.1 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF607 zf-CCHC PF00098.18 OAJ11179.1 - 0.0044 16.8 6.0 0.0075 16.1 4.2 1.4 1 0 0 1 1 1 1 Zinc knuckle Cytochrom_NNT PF03264.9 OAJ11179.1 - 0.079 12.3 3.3 0.12 11.7 2.3 1.3 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Aldo_ket_red PF00248.16 OAJ11190.1 - 2.5e-30 105.2 0.0 3.3e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Sybindin PF04099.7 OAJ11191.1 - 2.5e-07 30.4 1.0 4.7e-07 29.5 0.7 1.4 1 1 0 1 1 1 1 Sybindin-like family TFIIA PF03153.8 OAJ11191.1 - 8.1 6.2 8.8 13 5.5 6.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SMK-1 PF04802.10 OAJ11192.1 - 4.1e-72 241.7 2.8 1.2e-71 240.2 1.9 1.8 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 RVT_2 PF07727.9 OAJ11198.1 - 6.6e-16 58.0 0.0 8.5e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Autotransporter PF03797.14 OAJ11198.1 - 0.038 13.3 0.1 0.061 12.6 0.1 1.2 1 0 0 1 1 1 0 Autotransporter beta-domain RVT_3 PF13456.1 OAJ11198.1 - 0.052 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like Brr6_like_C_C PF10104.4 OAJ11199.1 - 7.9e-07 28.6 0.0 9e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain SNF5 PF04855.7 OAJ11199.1 - 0.15 11.5 0.0 0.15 11.4 0.0 1.0 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 rve PF00665.21 OAJ11200.1 - 6.1e-23 81.2 0.0 1.2e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain UBN2_2 PF14227.1 OAJ11200.1 - 1.9e-12 46.7 0.0 3.3e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ11200.1 - 3.4e-09 36.5 0.0 5.7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 OAJ11200.1 - 0.0088 15.4 0.1 0.025 13.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) gag_pre-integrs PF13976.1 OAJ11200.1 - 0.01 15.4 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_3 PF14244.1 OAJ11200.1 - 0.047 13.2 0.0 0.75 9.3 0.0 2.3 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type RVP PF00077.15 OAJ11200.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Pkinase PF00069.20 OAJ11207.1 - 1.4e-41 142.3 0.0 3.2e-27 95.3 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ11207.1 - 1.6e-16 60.1 0.0 5.3e-14 51.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 OAJ11207.1 - 0.0085 15.8 4.9 1 9.0 0.1 3.7 3 1 1 4 4 4 2 Phosphotransferase enzyme family Steroid_dh PF02544.11 OAJ11208.1 - 5.8e-23 81.3 1.9 9.4e-08 31.9 0.0 4.2 3 1 1 4 4 4 4 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 OAJ11208.1 - 0.0078 15.5 0.1 0.02 14.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Exo_endo_phos PF03372.18 OAJ11209.1 - 7.3e-20 71.9 0.1 1.6e-19 70.8 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 OAJ11209.1 - 2.2e-15 55.8 5.0 3.9e-07 29.5 0.2 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ11209.1 - 2e-08 33.8 5.9 3.6e-05 23.4 0.7 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 OAJ11209.1 - 5.7e-05 22.5 3.4 0.26 11.4 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 OAJ11209.1 - 0.00012 21.6 6.5 0.33 11.3 0.0 4.1 4 0 0 4 4 4 2 Leucine rich repeat CENP-B_dimeris PF09026.5 OAJ11209.1 - 0.026 14.7 1.8 0.08 13.1 1.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pam16 PF03656.8 OAJ11210.1 - 2.5e-11 43.4 10.4 4.2e-07 29.7 7.2 3.9 1 1 0 1 1 1 1 Pam16 SR-25 PF10500.4 OAJ11210.1 - 6.6 6.1 11.6 7.4 5.9 2.4 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GRASP55_65 PF04495.9 OAJ11215.1 - 5e-60 201.4 0.0 6.7e-49 165.4 0.0 2.3 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 OAJ11215.1 - 0.097 12.5 0.0 41 4.1 0.0 3.4 3 1 0 3 3 3 0 PDZ domain Myc_N PF01056.13 OAJ11215.1 - 0.12 11.5 3.9 0.18 10.9 2.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_60s PF00428.14 OAJ11215.1 - 1.1 9.7 12.3 0.077 13.4 3.5 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPR_MLP1_2 PF07926.7 OAJ11216.1 - 2.2e-23 82.4 16.3 2.2e-23 82.4 11.3 19.3 8 5 10 18 18 18 4 TPR/MLP1/MLP2-like protein rve PF00665.21 OAJ11223.1 - 3.9e-21 75.3 0.0 3e-20 72.5 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ11223.1 - 9.8e-16 57.7 0.0 2e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 OAJ11223.1 - 0.0016 18.3 3.4 0.0016 18.3 2.4 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ11223.1 - 0.0053 16.2 0.4 0.012 15.0 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 OAJ11223.1 - 0.017 15.5 0.0 0.053 14.0 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease rve_3 PF13683.1 OAJ11223.1 - 0.018 14.5 0.0 0.06 12.8 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain PLA2_B PF01735.13 OAJ11230.1 - 5.4e-14 51.2 0.0 8.7e-07 27.4 0.0 3.2 3 0 0 3 3 3 3 Lysophospholipase catalytic domain Pkinase PF00069.20 OAJ11231.1 - 2.4e-72 243.2 0.0 3.3e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ11231.1 - 2.5e-36 125.0 0.0 3.8e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ11231.1 - 1.5e-07 30.6 0.0 3.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like UBA_2 PF08587.6 OAJ11231.1 - 0.0073 16.4 0.4 0.025 14.7 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) RIO1 PF01163.17 OAJ11231.1 - 0.02 14.2 0.1 0.042 13.1 0.1 1.5 1 0 0 1 1 1 0 RIO1 family MULE PF10551.4 OAJ11238.1 - 0.00025 21.1 0.1 0.095 12.8 0.0 2.4 1 1 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 OAJ11238.1 - 0.0015 17.9 0.1 0.0033 16.8 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger GDNF PF02351.11 OAJ11238.1 - 0.051 14.0 1.3 0.094 13.2 0.9 1.5 1 1 0 1 1 1 0 GDNF/GAS1 domain DUF1128 PF06569.6 OAJ11238.1 - 0.058 13.1 0.1 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) Nha1_C PF08619.5 OAJ11247.1 - 0.00055 19.3 0.2 0.00064 19.1 0.2 1.0 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus FAM60A PF15396.1 OAJ11247.1 - 0.11 12.2 2.4 0.13 11.9 1.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Cwf_Cwc_15 PF04889.7 OAJ11247.1 - 0.18 11.4 8.8 0.24 11.0 6.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Macoilin PF09726.4 OAJ11247.1 - 2.3 6.3 11.5 2.7 6.1 8.0 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF4614 PF15391.1 OAJ11247.1 - 3.1 7.5 12.0 3.9 7.1 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Corona_nucleoca PF00937.13 OAJ11247.1 - 3.2 6.6 9.6 3.9 6.3 6.7 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Pheromone PF08015.6 OAJ11247.1 - 3.3 8.6 12.3 4.8 8.0 8.5 1.3 1 0 0 1 1 1 0 Fungal mating-type pheromone DUF1635 PF07795.6 OAJ11247.1 - 4.4 6.6 5.5 5.7 6.2 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF1754 PF08555.5 OAJ11247.1 - 6 7.5 8.9 5.2 7.7 4.7 1.8 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Fmp27 PF10344.4 OAJ11247.1 - 6.2 4.3 8.7 6.8 4.2 6.0 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 PP1c_bdg PF10488.4 OAJ11247.1 - 8.3 5.4 15.1 11 5.0 10.5 1.1 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region zf-C2H2 PF00096.21 OAJ11248.1 - 6.9e-05 22.9 0.1 0.00023 21.2 0.0 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ11248.1 - 0.14 12.5 0.1 0.14 12.5 0.1 2.1 3 0 0 3 3 3 0 C2H2-type zinc finger eIF3_subunit PF08597.5 OAJ11249.1 - 0.00076 19.1 0.0 0.00076 19.1 0.0 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Zip PF02535.17 OAJ11249.1 - 0.079 11.9 0.2 0.1 11.5 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF755 PF05501.6 OAJ11249.1 - 0.19 11.7 13.2 0.31 11.0 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RR_TM4-6 PF06459.7 OAJ11249.1 - 0.24 11.2 5.8 0.35 10.7 4.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 OAJ11249.1 - 0.28 9.1 7.9 0.35 8.8 5.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Rox3 PF08633.5 OAJ11249.1 - 0.49 10.6 7.1 0.9 9.8 4.3 1.6 1 1 1 2 2 2 0 Rox3 mediator complex subunit Med19 PF10278.4 OAJ11249.1 - 1.1 8.9 8.2 1.4 8.6 5.7 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Herpes_DNAp_acc PF04929.7 OAJ11249.1 - 1.5 7.6 8.9 1.9 7.3 6.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor MULE PF10551.4 OAJ11258.1 - 1.2e-14 54.2 0.0 3.3e-14 52.8 0.0 1.8 2 0 0 2 2 2 1 MULE transposase domain FAR1 PF03101.10 OAJ11258.1 - 1.1e-05 25.8 0.7 1.1e-05 25.8 0.5 3.3 4 0 0 4 4 4 1 FAR1 DNA-binding domain AFT PF08731.6 OAJ11258.1 - 0.003 17.7 0.1 0.003 17.7 0.1 1.9 2 0 0 2 2 2 1 Transcription factor AFT SURF4 PF02077.10 OAJ11260.1 - 4.5e-95 318.0 3.2 5.1e-95 317.8 2.2 1.0 1 0 0 1 1 1 1 SURF4 family Trp_oprn_chp PF09534.5 OAJ11260.1 - 1.8 8.1 4.7 1 8.9 0.7 2.2 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) HR_lesion PF05514.6 OAJ11260.1 - 10 5.9 8.7 2.1 8.2 0.9 3.1 3 1 1 4 4 4 0 HR-like lesion-inducing Citrate_synt PF00285.16 OAJ11261.1 - 2.7e-18 65.8 0.1 1.3e-15 56.9 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 OAJ11261.1 - 1.8e-14 53.5 0.1 5e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 OAJ11261.1 - 3.2e-11 43.5 0.0 8.3e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 OAJ11261.1 - 1.3e-06 27.9 0.0 2.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 OAJ11261.1 - 9.2e-05 22.0 0.0 0.0003 20.3 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.1 OAJ11261.1 - 0.0054 15.9 0.0 0.022 13.9 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain RVT_1 PF00078.22 OAJ11268.1 - 3.4e-08 33.1 0.1 6.1e-06 25.7 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ11268.1 - 0.00011 22.6 0.1 0.00029 21.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ11268.1 - 0.0017 18.2 0.0 0.0045 16.8 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ11268.1 - 0.0057 16.4 0.6 0.017 14.9 0.2 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Serglycin PF04360.7 OAJ11269.1 - 0.0033 17.1 2.4 0.0095 15.6 0.9 2.1 2 0 0 2 2 2 1 Serglycin zf-C2H2_4 PF13894.1 OAJ11269.1 - 0.13 12.6 10.1 2 8.9 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 OAJ11269.1 - 0.16 12.3 0.2 0.16 12.3 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF3246 PF11596.3 OAJ11269.1 - 6 6.0 9.1 13 5.0 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) tRNA-synt_2b PF00587.20 OAJ11270.1 - 6.2e-33 113.8 0.0 1.1e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 OAJ11270.1 - 1.1e-17 64.0 3.0 1.1e-17 64.0 2.1 1.5 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain FlxA PF14282.1 OAJ11270.1 - 0.094 12.6 2.8 0.067 13.1 0.8 1.6 2 0 0 2 2 2 0 FlxA-like protein IFT57 PF10498.4 OAJ11270.1 - 0.13 11.0 5.3 3 6.5 0.7 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DcpS_C PF11969.3 OAJ11271.1 - 0.014 15.6 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 OAJ11271.1 - 0.017 15.6 0.1 0.047 14.2 0.0 1.7 2 0 0 2 2 2 0 HIT domain COesterase PF00135.23 OAJ11272.1 - 1.1e-57 195.9 0.0 4.1e-57 194.1 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ11272.1 - 3e-11 43.2 0.2 1.6e-10 40.9 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 OAJ11272.1 - 0.00057 19.2 0.1 0.0013 18.0 0.1 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 OAJ11272.1 - 0.0075 16.0 0.6 0.017 14.8 0.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAJ11272.1 - 0.052 12.9 0.2 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 OAJ11272.1 - 0.14 11.3 0.1 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Nuc_sug_transp PF04142.10 OAJ11281.1 - 2.3e-07 30.1 0.3 3.7e-07 29.5 0.2 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter CitMHS PF03600.11 OAJ11281.1 - 2.1e-05 23.2 0.0 4.2e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Citrate transporter EamA PF00892.15 OAJ11281.1 - 7.8e-05 22.7 3.4 7.8e-05 22.7 2.4 3.9 3 1 0 3 3 3 1 EamA-like transporter family TPT PF03151.11 OAJ11281.1 - 0.48 10.0 16.1 0.14 11.8 1.3 3.1 2 1 0 2 2 2 0 Triose-phosphate Transporter family CoxIIa PF08113.6 OAJ11281.1 - 2.6 7.8 7.3 0.16 11.7 0.6 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family MFS_2 PF13347.1 OAJ11282.1 - 6.2e-11 41.3 1.0 6.2e-11 41.3 0.7 2.8 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.11 OAJ11282.1 - 0.0083 14.8 40.5 0.0038 16.0 24.6 2.8 2 2 0 2 2 2 1 Major Facilitator Superfamily PsaM PF07465.8 OAJ11282.1 - 3.7 7.2 6.5 0.28 10.8 0.8 1.9 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) LSM PF01423.17 OAJ11283.1 - 4.4e-21 74.1 0.1 5.2e-21 73.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 OAJ11283.1 - 0.0004 20.2 0.0 0.00047 20.0 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain zf-CCCH PF00642.19 OAJ11284.1 - 2.3e-07 30.3 2.2 4e-07 29.5 1.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_6 PF14259.1 OAJ11284.1 - 8.5e-07 28.8 0.0 1.9e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ11284.1 - 1e-06 28.4 0.1 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 OAJ11284.1 - 1.3e-06 28.4 0.0 3.1e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.1 OAJ11284.1 - 4.9e-05 23.0 0.0 9.2e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 OAJ11284.1 - 0.012 15.2 0.0 0.028 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ11284.1 - 0.45 10.3 0.0 0.45 10.3 0.0 2.6 4 0 0 4 4 4 0 RNA binding motif LrgB PF04172.11 OAJ11285.1 - 2.3e-21 75.9 4.0 2.5e-21 75.8 2.8 1.0 1 0 0 1 1 1 1 LrgB-like family FAM70 PF14967.1 OAJ11285.1 - 0.28 10.3 5.5 0.45 9.6 3.8 1.4 1 1 0 1 1 1 0 FAM70 protein Gate PF07670.9 OAJ11285.1 - 3.7 7.4 7.3 11 6.0 4.7 2.1 1 1 0 1 1 1 0 Nucleoside recognition Fork_head PF00250.13 OAJ11294.1 - 3.9e-11 42.8 0.0 1.4e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Fork head domain Phostensin_N PF13916.1 OAJ11294.1 - 0.6 10.1 15.2 0.55 10.2 1.9 3.1 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal FimP PF09766.4 OAJ11294.1 - 3 6.8 15.4 0.6 9.1 3.2 2.1 2 0 0 2 2 2 0 Fms-interacting protein Spt20 PF12090.3 OAJ11294.1 - 9.5 5.5 12.3 8.8 5.6 0.8 2.2 2 0 0 2 2 2 0 Spt20 family Cellulase PF00150.13 OAJ11296.1 - 0.003 16.8 0.0 0.0038 16.4 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RVT_1 PF00078.22 OAJ11305.1 - 0.067 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.13 OAJ11305.1 - 0.08 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Phage_integrase PF00589.17 OAJ11306.1 - 0.007 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family ASFV_J13L PF05568.6 OAJ11306.1 - 0.028 13.9 2.7 0.059 12.8 1.9 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein 2OG-FeII_Oxy_3 PF13640.1 OAJ11309.1 - 2.7e-09 37.4 0.0 4.8e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 OAJ11309.1 - 1.1e-05 24.9 0.0 9.8e-05 21.9 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ11309.1 - 0.097 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Vps5 PF09325.5 OAJ11310.1 - 1.6e-58 197.7 5.0 1.6e-58 197.7 3.4 3.8 3 1 1 4 4 4 1 Vps5 C terminal like RmlD_sub_bind PF04321.12 OAJ11310.1 - 7.7e-48 162.8 0.0 7.7e-48 162.8 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.16 OAJ11310.1 - 5.6e-23 81.6 0.0 1.4e-22 80.2 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PX PF00787.19 OAJ11310.1 - 5e-22 77.8 0.0 1.9e-21 75.9 0.0 2.0 1 0 0 1 1 1 1 PX domain NAD_binding_4 PF07993.7 OAJ11310.1 - 2.8e-07 29.7 0.1 1e-05 24.6 0.0 2.8 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 OAJ11310.1 - 9.2e-06 24.7 0.2 0.0002 20.3 0.1 2.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein MIP-T3 PF10243.4 OAJ11310.1 - 8.8 4.6 102.9 0.012 14.1 36.9 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 BTB PF00651.26 OAJ11311.1 - 2.4e-12 46.7 0.1 1.4e-05 25.0 0.0 3.4 3 0 0 3 3 3 2 BTB/POZ domain zf-U1 PF06220.7 OAJ11312.1 - 6.6e-06 25.5 0.0 1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 U1 zinc finger HsbA PF12296.3 OAJ11321.1 - 2e-13 50.2 12.1 3e-13 49.7 8.4 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A FUN14 PF04930.10 OAJ11321.1 - 0.076 13.3 2.6 0.19 12.0 1.8 2.0 1 1 0 1 1 1 0 FUN14 family Baculo_PEP_C PF04513.7 OAJ11321.1 - 1.9 8.3 9.1 3.8 7.3 6.1 1.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cupin_8 PF13621.1 OAJ11322.1 - 4.8e-24 85.2 0.0 1.1e-23 84.0 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 OAJ11322.1 - 1.3e-07 31.2 0.1 7.6e-06 25.3 0.0 2.4 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 OAJ11322.1 - 4.8e-05 23.5 0.0 0.002 18.3 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 OAJ11322.1 - 0.1 12.1 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 Cupin domain HsbA PF12296.3 OAJ11323.1 - 8.5e-16 57.9 8.9 1.2e-15 57.5 6.2 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Reo_sigmaC PF04582.7 OAJ11323.1 - 0.19 10.8 3.1 0.25 10.5 1.7 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 OAJ11323.1 - 1.2 8.9 9.6 2 8.2 6.4 1.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HsbA PF12296.3 OAJ11324.1 - 4e-16 59.0 13.0 6e-16 58.4 9.0 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Pox_A6 PF04924.7 OAJ11324.1 - 0.08 11.7 0.5 0.083 11.6 0.3 1.2 1 0 0 1 1 1 0 Poxvirus A6 protein Reo_sigmaC PF04582.7 OAJ11324.1 - 0.097 11.8 4.7 0.12 11.5 3.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3713 PF12506.3 OAJ11324.1 - 0.72 9.9 5.7 0.22 11.6 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) DivIVA PF05103.8 OAJ11324.1 - 0.78 9.7 4.2 0.16 11.9 0.7 1.5 2 0 0 2 2 2 0 DivIVA protein DUF1341 PF07071.6 OAJ11324.1 - 1.4 8.3 7.9 0.45 10.0 0.2 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1341) Phage_int_SAM_1 PF02899.12 OAJ11335.1 - 0.065 13.3 0.0 10 6.3 0.0 2.8 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain CFEM PF05730.6 OAJ11343.1 - 0.0032 17.2 10.6 0.024 14.4 3.0 2.3 2 0 0 2 2 2 2 CFEM domain CFEM PF05730.6 OAJ11344.1 - 5.7e-08 32.4 10.1 8.4e-08 31.9 7.0 1.2 1 0 0 1 1 1 1 CFEM domain TIL PF01826.12 OAJ11344.1 - 0.58 10.3 7.9 0.96 9.6 5.5 1.3 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain RRM_1 PF00076.17 OAJ11345.1 - 6.5e-13 48.1 0.0 1e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ11345.1 - 3.9e-09 36.3 0.0 6.3e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ11345.1 - 0.0021 17.8 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YqeY PF09424.5 OAJ11346.1 - 8.6e-24 84.0 1.0 1.1e-23 83.6 0.7 1.1 1 0 0 1 1 1 1 Yqey-like protein DUF3365 PF11845.3 OAJ11346.1 - 0.03 14.1 0.5 0.04 13.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) DUF4254 PF14063.1 OAJ11346.1 - 0.038 13.5 0.6 0.061 12.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) WD40 PF00400.27 OAJ11347.1 - 1.4e-13 50.1 14.8 8.8e-06 25.4 0.1 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ATP-synt_D PF01813.12 OAJ11348.1 - 1.6e-66 223.6 3.0 2.6e-66 222.9 2.0 1.3 1 0 0 1 1 1 1 ATP synthase subunit D Daxx PF03344.10 OAJ11348.1 - 0.031 12.7 17.9 0.044 12.2 12.4 1.1 1 0 0 1 1 1 0 Daxx Family DUF876 PF05936.7 OAJ11348.1 - 0.095 11.1 0.4 1.2 7.4 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF876) K_channel_TID PF07941.6 OAJ11348.1 - 0.26 11.5 12.4 0.75 10.0 8.6 1.8 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Nop14 PF04147.7 OAJ11348.1 - 0.55 8.0 16.3 0.29 8.9 9.8 1.7 2 0 0 2 2 2 0 Nop14-like family NOA36 PF06524.7 OAJ11348.1 - 9.7 5.3 8.3 15 4.7 5.8 1.3 1 0 0 1 1 1 0 NOA36 protein CFEM PF05730.6 OAJ11349.1 - 9e-07 28.6 12.5 2.1e-06 27.4 8.6 1.7 1 1 0 1 1 1 1 CFEM domain Toxin_3 PF00537.13 OAJ11349.1 - 0.021 14.6 5.7 0.052 13.4 3.9 1.5 1 0 0 1 1 1 0 Scorpion toxin-like domain EXOSC1 PF10447.4 OAJ11354.1 - 9.6e-27 92.7 0.0 1.8e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 CENP-F_leu_zip PF10473.4 OAJ11355.1 - 0.059 13.2 16.8 4.9 7.0 0.1 3.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CR6_interact PF10147.4 OAJ11355.1 - 0.065 12.5 4.8 0.059 12.6 2.3 1.6 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 GAS PF13851.1 OAJ11355.1 - 0.12 11.6 10.3 0.84 8.7 4.3 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding HALZ PF02183.13 OAJ11355.1 - 0.26 11.0 7.4 4 7.2 0.1 4.8 5 0 0 5 5 5 0 Homeobox associated leucine zipper DivIVA PF05103.8 OAJ11355.1 - 0.47 10.5 13.9 4.4 7.3 0.0 3.7 2 1 1 3 3 3 0 DivIVA protein Phlebovirus_NSM PF07246.6 OAJ11355.1 - 0.47 9.5 6.8 1.2 8.1 2.8 2.2 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Spc7 PF08317.6 OAJ11355.1 - 6.9 5.2 12.2 1.1 7.8 0.2 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein WEMBL PF05701.6 OAJ11355.1 - 7.8 4.8 32.0 2.2 6.6 17.6 2.6 2 1 0 2 2 2 0 Weak chloroplast movement under blue light TFIIS_M PF07500.9 OAJ11356.1 - 2.1e-18 66.4 0.0 4e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 OAJ11356.1 - 6.1e-11 41.8 6.9 9.5e-11 41.2 4.8 1.3 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.8 OAJ11356.1 - 1.1e-07 32.3 0.0 2.1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 SPOC domain DUF2890 PF11081.3 OAJ11356.1 - 0.21 11.6 11.3 0.83 9.6 7.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) zf-RING_2 PF13639.1 OAJ11356.1 - 0.45 10.3 5.0 0.82 9.5 3.5 1.4 1 0 0 1 1 1 0 Ring finger domain PHD_2 PF13831.1 OAJ11356.1 - 0.78 9.1 1.6 1.3 8.3 1.1 1.4 1 0 0 1 1 1 0 PHD-finger Peptidase_C97 PF05903.9 OAJ11357.1 - 2.8e-15 56.4 0.0 1.7e-11 44.1 0.0 2.2 2 0 0 2 2 2 2 PPPDE putative peptidase domain Yippee-Mis18 PF03226.9 OAJ11364.1 - 3.7e-20 71.7 0.5 4.1e-20 71.6 0.4 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 OAJ11364.1 - 0.13 12.1 1.3 0.27 11.1 0.9 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I Evr1_Alr PF04777.8 OAJ11364.1 - 0.15 11.9 0.5 0.44 10.4 0.0 1.9 1 1 1 2 2 2 0 Erv1 / Alr family Endonuclease_7 PF02945.10 OAJ11364.1 - 0.16 11.6 2.4 0.51 10.0 1.7 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII UPF0047 PF01894.12 OAJ11365.1 - 6.1e-41 138.9 0.0 8.6e-41 138.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 H_lectin PF09458.5 OAJ11376.1 - 4.7e-16 58.2 0.0 1.5e-06 27.7 0.0 3.5 3 1 0 3 3 3 3 H-type lectin domain GCR1_C PF12550.3 OAJ11378.1 - 9.7e-11 41.3 0.7 7.7e-10 38.5 0.0 2.2 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes RVT_1 PF00078.22 OAJ11384.1 - 1.4e-19 70.3 0.0 2.6e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ11384.1 - 2.9e-13 49.9 0.0 5.7e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ11384.1 - 0.00058 20.2 0.0 0.0027 18.1 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAJ11384.1 - 0.16 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease HSF_DNA-bind PF00447.12 OAJ11397.1 - 1.1e-34 118.7 0.5 1.6e-34 118.2 0.4 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding SRF-TF PF00319.13 OAJ11398.1 - 8.1e-19 66.5 0.0 1.4e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) UPF0172 PF03665.8 OAJ11399.1 - 1e-42 145.8 0.0 1.3e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 OAJ11399.1 - 0.15 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FAD_binding_1 PF00667.15 OAJ11406.1 - 1.7e-55 187.8 0.0 3.7e-55 186.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 OAJ11406.1 - 9.5e-32 109.9 0.2 2e-31 108.9 0.1 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 OAJ11406.1 - 5.7e-21 75.1 0.0 2.4e-20 73.0 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain W2 PF02020.13 OAJ11407.1 - 1.7e-17 63.1 0.3 1.7e-17 63.1 0.2 2.3 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon zf-Nse PF11789.3 OAJ11409.1 - 6.7e-14 51.1 0.1 1.3e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 OAJ11409.1 - 0.0056 16.6 0.0 0.026 14.4 0.0 2.1 2 0 0 2 2 2 1 U-box domain DUF3246 PF11596.3 OAJ11409.1 - 0.013 14.8 5.3 0.029 13.6 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) zf-RING_UBOX PF13445.1 OAJ11409.1 - 0.019 14.6 0.0 0.056 13.1 0.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Snapin_Pallidin PF14712.1 OAJ11409.1 - 0.1 12.9 1.2 0.23 11.7 0.8 1.6 1 0 0 1 1 1 0 Snapin/Pallidin DnaJ PF00226.26 OAJ11418.1 - 1e-13 50.8 0.1 7.2e-13 48.0 0.0 2.4 2 1 0 2 2 2 1 DnaJ domain zf-CSL PF05207.8 OAJ11418.1 - 3.8e-09 35.9 0.7 3.8e-09 35.9 0.5 2.3 2 1 0 2 2 2 1 CSL zinc finger JAB PF01398.16 OAJ11419.1 - 1.4e-14 53.7 0.0 3.5e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 OAJ11419.1 - 4.9e-07 29.2 0.3 1.2e-06 28.0 0.2 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain NPL4 PF05021.10 OAJ11419.1 - 0.22 10.6 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 NPL4 family APH PF01636.18 OAJ11420.1 - 1.4e-08 34.7 0.0 2.1e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3673 PF12425.3 OAJ11420.1 - 0.024 14.4 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) LRR_4 PF12799.2 OAJ11421.1 - 2.1e-32 110.1 25.1 1.1e-06 28.0 0.8 8.0 6 2 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ11421.1 - 2.3e-22 78.4 24.2 3.6e-09 36.2 1.4 5.8 4 1 0 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 OAJ11421.1 - 9.8e-13 46.2 34.1 0.26 11.4 0.4 10.8 10 1 1 11 11 11 6 Leucine Rich Repeat LRR_6 PF13516.1 OAJ11421.1 - 2.2e-06 27.1 21.7 2.6 8.4 0.1 9.0 9 1 1 10 10 10 3 Leucine Rich repeat LRR_7 PF13504.1 OAJ11421.1 - 3.7e-05 23.2 39.6 0.93 9.9 0.1 10.9 12 0 0 12 12 12 4 Leucine rich repeat LRR_9 PF14580.1 OAJ11421.1 - 7.6e-05 22.3 12.1 0.016 14.7 0.1 4.5 3 1 1 4 4 4 2 Leucine-rich repeat PIF1 PF05970.9 OAJ11428.1 - 7.3e-103 344.3 0.0 9.5e-103 343.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ11428.1 - 3.6e-22 78.9 0.1 7.4e-22 77.9 0.1 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 OAJ11428.1 - 9.6e-08 31.8 0.1 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 OAJ11428.1 - 5.2e-07 27.8 0.0 1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 OAJ11428.1 - 0.0034 17.5 0.0 0.012 15.7 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Zeta_toxin PF06414.7 OAJ11428.1 - 0.0054 15.8 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 OAJ11428.1 - 0.011 15.4 0.2 0.033 13.9 0.2 1.7 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 OAJ11428.1 - 0.065 12.1 0.0 0.14 10.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein KAP_NTPase PF07693.9 OAJ11428.1 - 0.24 10.3 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain GRP PF07172.6 OAJ11439.1 - 0.0088 16.4 6.6 0.0088 16.4 4.6 2.8 3 0 0 3 3 3 2 Glycine rich protein family Hpt PF01627.18 OAJ11451.1 - 5.2e-11 42.4 0.1 9.8e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Hpt domain Med3 PF11593.3 OAJ11451.1 - 1.1 8.3 5.8 1.1 8.3 4.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF605 PF04652.11 OAJ11451.1 - 2.5 7.3 13.6 3 7.1 9.5 1.2 1 0 0 1 1 1 0 Vta1 like IPK PF03770.11 OAJ11452.1 - 3.9e-36 124.5 0.0 1.7e-21 76.7 0.0 2.1 2 0 0 2 2 2 2 Inositol polyphosphate kinase Ribonuc_red_lgC PF02867.10 OAJ11453.1 - 1.4e-210 700.4 0.0 1.9e-210 700.0 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 OAJ11453.1 - 3.4e-24 84.4 0.0 7.4e-24 83.3 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 OAJ11453.1 - 2e-17 63.4 0.3 7.1e-17 61.6 0.2 2.1 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.1 OAJ11453.1 - 0.0017 16.4 0.0 0.0028 15.8 0.0 1.3 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase DisA_N PF02457.11 OAJ11453.1 - 0.023 13.8 0.0 0.056 12.5 0.0 1.6 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding RVT_1 PF00078.22 OAJ11459.1 - 7.3e-27 94.1 0.0 1.1e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAJ11459.1 - 2.3e-11 44.1 0.0 3.9e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAJ11459.1 - 0.011 15.5 0.0 0.041 13.6 0.0 2.0 1 1 0 1 1 1 0 Reverse transcriptase-like Exo_endo_phos_2 PF14529.1 OAJ11460.1 - 2.1e-12 46.6 0.0 4.1e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ11460.1 - 3e-08 33.9 0.0 5.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SRP54 PF00448.17 OAJ11460.1 - 0.012 15.0 0.0 0.027 13.9 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain WD40 PF00400.27 OAJ11462.1 - 5.1e-21 73.7 2.9 2.6e-07 30.2 0.2 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 OAJ11462.1 - 0.0045 15.1 0.1 0.011 13.9 0.0 1.6 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Ras PF00071.17 OAJ11463.1 - 1.3e-53 180.6 0.0 1.5e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ11463.1 - 9.9e-16 58.3 0.0 1.3e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ11463.1 - 1.5e-06 27.5 0.0 2.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF4442 PF14539.1 OAJ11473.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) DUF4218 PF13960.1 OAJ11474.1 - 0.00018 20.9 0.0 0.00044 19.6 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) RNA_pol_A_bac PF01000.21 OAJ11476.1 - 3.1e-27 94.9 0.0 4.7e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 OAJ11476.1 - 1e-15 56.5 0.0 1.4e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Glyco_transf_28 PF03033.15 OAJ11485.1 - 8.3e-28 96.8 0.1 2.6e-27 95.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 OAJ11485.1 - 3.5e-08 32.8 0.3 0.00093 18.6 0.0 3.2 3 0 0 3 3 3 2 GRAM domain UDPGT PF00201.13 OAJ11485.1 - 0.00016 20.4 0.0 0.00028 19.5 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.24 OAJ11485.1 - 0.094 12.9 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 PH domain Glyco_tran_28_C PF04101.11 OAJ11485.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DUF423 PF04241.10 OAJ11486.1 - 6.4e-24 83.6 3.3 1.5e-23 82.5 2.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Trypsin PF00089.21 OAJ11496.1 - 0.066 12.7 0.1 0.066 12.7 0.1 1.1 1 0 0 1 1 1 0 Trypsin zf-P11 PF03854.9 OAJ11496.1 - 1 8.8 6.3 5.1 6.6 0.3 2.9 2 1 1 3 3 3 0 P-11 zinc finger zf-C3HC4_2 PF13923.1 OAJ11496.1 - 1.9 8.6 5.4 19 5.4 0.0 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-dskA_traR PF01258.12 OAJ11496.1 - 5.5 6.8 7.1 10 5.9 0.1 2.8 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Lon_C PF05362.8 OAJ11503.1 - 1.7e-05 24.2 0.0 1.7e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain GDH_N PF12466.3 OAJ11503.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal SPOUT_MTase_2 PF14419.1 OAJ11504.1 - 0.097 11.8 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP LigB PF02900.13 OAJ11505.1 - 1.4e-30 106.1 0.6 7.4e-30 103.8 0.4 1.8 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Mrr_cat PF04471.7 OAJ11505.1 - 0.023 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease Transposase_21 PF02992.9 OAJ11514.1 - 5.2e-12 45.3 0.0 9.1e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ11514.1 - 0.0027 17.1 0.0 0.0059 16.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Histone PF00125.19 OAJ11523.1 - 2e-28 98.3 0.4 3.5e-28 97.5 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 NTP_transferase PF00483.18 OAJ11523.1 - 4.1e-16 59.0 0.0 8.8e-16 57.9 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase CENP-S PF15630.1 OAJ11523.1 - 0.0023 18.0 0.0 0.0054 16.8 0.0 1.6 1 0 0 1 1 1 1 Kinetochore component CENP-S MannoseP_isomer PF01050.13 OAJ11523.1 - 0.22 11.1 0.1 0.38 10.3 0.1 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase RVT_2 PF07727.9 OAJ11524.1 - 9.1e-87 290.0 0.0 1.2e-86 289.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ11524.1 - 1.2e-18 67.4 0.5 2.6e-18 66.2 0.1 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 OAJ11524.1 - 0.00022 20.6 0.6 0.004 16.6 0.4 2.8 1 1 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ11524.1 - 0.038 13.3 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF221 PF02714.10 OAJ11525.1 - 6e-83 278.3 18.8 6.2e-83 278.3 12.4 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAJ11525.1 - 5e-35 120.3 1.0 5e-35 120.3 0.7 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 OAJ11525.1 - 4.1e-15 56.0 0.0 1e-14 54.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RhoGEF PF00621.15 OAJ11533.1 - 9.6e-13 48.3 0.0 5.3e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain Menin PF05053.8 OAJ11534.1 - 3.6 5.6 5.6 5.4 5.0 3.9 1.2 1 0 0 1 1 1 0 Menin DUF605 PF04652.11 OAJ11534.1 - 7.2 5.8 18.5 1.4 8.2 8.8 2.1 2 0 0 2 2 2 0 Vta1 like Esterase PF00756.15 OAJ11535.1 - 0.00033 20.1 0.0 0.00052 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 OAJ11535.1 - 0.0087 15.8 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF605 PF04652.11 OAJ11535.1 - 0.52 9.6 14.8 0.74 9.1 10.2 1.2 1 0 0 1 1 1 0 Vta1 like Dimer_Tnp_hAT PF05699.9 OAJ11547.1 - 9.2e-21 73.2 0.1 1.7e-20 72.3 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Retrotrans_gag PF03732.12 OAJ11560.1 - 2.5e-12 46.6 0.2 1.4e-11 44.2 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF2205 PF10224.4 OAJ11560.1 - 0.0064 16.0 1.3 0.014 14.9 0.9 1.5 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) TSC22 PF01166.13 OAJ11560.1 - 0.038 13.9 1.0 0.12 12.3 0.2 2.2 3 0 0 3 3 3 0 TSC-22/dip/bun family RVT_1 PF00078.22 OAJ11561.1 - 4.7e-26 91.4 0.1 1.1e-25 90.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ11561.1 - 3.1e-20 72.4 0.0 9.9e-20 70.8 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 OAJ11561.1 - 4.1e-08 32.7 0.0 1.2e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 OAJ11561.1 - 2.3e-05 24.8 0.0 5.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ11561.1 - 7.1e-05 22.5 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF2346 PF09803.4 OAJ11572.1 - 7.1e-09 35.4 0.0 1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) SR-25 PF10500.4 OAJ11572.1 - 0.031 13.7 6.1 0.037 13.4 4.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hydrolase_6 PF13344.1 OAJ11573.1 - 6.9e-20 70.8 0.0 1.4e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAJ11573.1 - 3.9e-11 43.7 0.0 1.6e-10 41.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAJ11573.1 - 1.3e-08 34.4 0.1 2.3e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 OAJ11573.1 - 0.0011 19.2 0.0 0.067 13.4 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 OAJ11573.1 - 0.012 14.9 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Fcf1 PF04900.7 OAJ11574.1 - 8.2e-39 131.7 0.5 1.2e-38 131.2 0.4 1.3 1 0 0 1 1 1 1 Fcf1 Tannase PF07519.6 OAJ11575.1 - 5.7e-72 242.9 0.0 1.6e-64 218.3 0.0 2.8 2 1 0 2 2 2 2 Tannase and feruloyl esterase CLN3 PF02487.12 OAJ11576.1 - 2.3e-64 217.7 10.6 9.2e-28 97.1 0.0 4.0 3 1 1 4 4 4 4 CLN3 protein PI3K_1B_p101 PF10486.4 OAJ11576.1 - 0.016 12.8 0.4 0.023 12.3 0.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nucleoplasmin PF03066.10 OAJ11576.1 - 0.24 10.8 6.5 1.2 8.6 3.8 2.1 2 0 0 2 2 2 0 Nucleoplasmin BSP_II PF05432.6 OAJ11576.1 - 0.32 10.2 8.1 0.48 9.6 5.6 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) NOA36 PF06524.7 OAJ11576.1 - 3 7.0 5.2 6.1 6.0 3.6 1.4 1 0 0 1 1 1 0 NOA36 protein UreD PF01774.12 OAJ11577.1 - 2e-49 167.9 0.0 7.6e-49 166.0 0.0 1.9 1 1 0 1 1 1 1 UreD urease accessory protein DUF2613 PF11021.3 OAJ11585.1 - 0.95 9.2 4.3 0.29 10.8 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Fork_head PF00250.13 OAJ11586.1 - 2e-21 75.8 0.0 4.1e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Fork head domain tRNA-synt_2d PF01409.15 OAJ11587.1 - 7.4e-87 290.6 0.0 1e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 OAJ11587.1 - 4.9e-06 26.2 0.0 8.9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 OAJ11587.1 - 4.8e-05 22.3 1.1 0.0012 17.6 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) DUF89 PF01937.14 OAJ11599.1 - 6.9e-107 357.3 0.0 1.2e-106 356.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function DUF89 WD40 PF00400.27 OAJ11611.1 - 5.7e-22 76.7 10.6 1.9e-06 27.4 0.0 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 OAJ11611.1 - 0.2 11.3 0.2 41 3.7 0.0 3.3 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Mg_trans_NIPA PF05653.9 OAJ11612.1 - 1e-107 359.5 15.1 1.4e-107 359.1 10.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 OAJ11612.1 - 2e-08 34.3 1.5 2e-08 34.3 1.0 3.0 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 OAJ11612.1 - 9.8e-05 22.3 6.6 9.8e-05 22.3 4.6 3.1 3 1 0 3 3 3 2 EamA-like transporter family Ribosomal_L11_N PF03946.9 OAJ11613.1 - 4.3e-18 64.5 0.1 7.1e-18 63.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 OAJ11613.1 - 3.7e-11 42.9 0.1 6.5e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain URO-D PF01208.12 OAJ11614.1 - 2.9e-130 434.1 0.0 3.3e-130 433.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Rifin_STEVOR PF02009.11 OAJ11624.1 - 0.063 12.9 0.7 0.12 11.9 0.5 1.4 1 1 0 1 1 1 0 Rifin/stevor family Nop25 PF09805.4 OAJ11625.1 - 2.6 8.1 12.1 0.2 11.7 0.6 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) K_channel_TID PF07941.6 OAJ11625.1 - 3.4 7.9 19.4 1 9.6 8.7 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain zf-C2HC_2 PF13913.1 OAJ11627.1 - 0.07 12.8 0.3 0.21 11.3 0.2 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Phage_integrase PF00589.17 OAJ11637.1 - 0.087 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family HMG_box PF00505.14 OAJ11638.1 - 1.2e-16 60.6 21.9 5.3e-09 36.2 0.8 3.7 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ11638.1 - 1e-15 57.8 14.4 5.6e-10 39.4 0.4 2.8 3 0 0 3 3 3 2 HMG-box domain HMG_box_5 PF14887.1 OAJ11638.1 - 0.0083 15.8 0.2 0.027 14.2 0.1 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box 5 YABBY PF04690.8 OAJ11638.1 - 5.8 7.1 12.4 0.49 10.6 0.1 3.1 3 1 1 4 4 4 0 YABBY protein adh_short PF00106.20 OAJ11639.1 - 4.1e-20 72.3 0.3 6.6e-20 71.6 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ11639.1 - 7.8e-09 35.4 0.5 1.7e-08 34.3 0.3 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ11639.1 - 3.2e-05 23.8 0.7 4.3e-05 23.4 0.1 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase rve PF00665.21 OAJ11646.1 - 9.3e-22 77.3 0.0 2e-20 73.1 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.1 OAJ11646.1 - 7.8e-11 41.6 0.0 6.3e-10 38.7 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAJ11646.1 - 5e-09 36.5 0.0 1.2e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 OAJ11646.1 - 4.1e-05 23.1 0.1 8.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Phage_integrase PF00589.17 OAJ11646.1 - 6.3e-05 22.7 0.0 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family RVP PF00077.15 OAJ11646.1 - 0.00022 21.1 0.0 0.0005 19.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.5 OAJ11646.1 - 0.0024 17.2 0.0 0.0058 16.0 0.0 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 OAJ11646.1 - 0.025 13.9 0.0 0.045 13.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_IS240 PF13610.1 OAJ11646.1 - 0.031 14.2 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 DDE domain RVP_2 PF08284.6 OAJ11646.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Sensor_TM1 PF13755.1 OAJ11647.1 - 0.017 14.6 0.1 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain AAA_27 PF13514.1 OAJ11657.1 - 0.0052 14.5 0.4 0.0064 14.2 0.3 1.0 1 0 0 1 1 1 1 AAA domain Spectrin PF00435.16 OAJ11657.1 - 0.024 14.8 0.4 0.044 14.0 0.3 1.4 1 0 0 1 1 1 0 Spectrin repeat TPR_MLP1_2 PF07926.7 OAJ11657.1 - 0.057 13.1 1.3 0.075 12.7 0.9 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.16 OAJ11657.1 - 0.093 12.7 2.1 0.26 11.2 0.6 2.0 1 1 1 2 2 2 0 bZIP transcription factor DDE_3 PF13358.1 OAJ11659.1 - 5.9e-31 107.1 0.0 1.2e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 OAJ11659.1 - 1.6e-08 34.6 0.0 3.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 OAJ11659.1 - 5.6e-07 30.2 0.1 2.4e-06 28.2 0.0 2.1 1 1 1 2 2 2 1 Homeodomain-like domain DDE_1 PF03184.14 OAJ11659.1 - 2.1e-06 27.0 0.0 4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 OAJ11659.1 - 7.6e-05 22.1 0.1 0.00018 20.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 OAJ11659.1 - 9e-05 22.4 0.5 0.0016 18.4 0.0 2.3 2 0 0 2 2 2 1 Transposase DDE_Tnp_ISAZ013 PF07592.6 OAJ11659.1 - 0.00097 17.9 0.0 0.64 8.7 0.0 2.2 2 0 0 2 2 2 2 Rhodopirellula transposase DDE domain rve PF00665.21 OAJ11659.1 - 0.0016 18.5 0.0 0.0039 17.2 0.0 1.8 1 1 0 1 1 1 1 Integrase core domain DUF1849 PF08904.6 OAJ11659.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1849) DUF3439 PF11921.3 OAJ11660.1 - 0.14 11.9 1.7 0.86 9.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Pantoate_ligase PF02569.10 OAJ11671.1 - 8.2e-81 270.8 0.0 8e-80 267.5 0.0 2.0 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase PPR_2 PF13041.1 OAJ11672.1 - 3.3e-14 52.5 0.0 0.0041 17.0 0.0 6.5 5 1 1 6 6 6 4 PPR repeat family PPR_3 PF13812.1 OAJ11672.1 - 1.7e-13 49.6 17.9 0.0063 16.7 0.1 7.9 8 0 0 8 8 8 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 OAJ11672.1 - 4.7e-07 29.1 4.7 0.068 12.6 0.0 5.5 6 1 0 6 6 6 2 PPR repeat PPR PF01535.15 OAJ11672.1 - 1.2e-05 24.9 8.9 0.063 13.2 0.0 6.2 6 1 0 6 6 6 2 PPR repeat RhoGEF PF00621.15 OAJ11681.1 - 9.2e-29 100.5 0.2 1.7e-28 99.7 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain Nucleic_acid_bd PF13820.1 OAJ11681.1 - 0.015 14.8 0.4 0.084 12.4 0.0 2.4 2 0 0 2 2 2 0 Putative nucleic acid-binding region BUD22 PF09073.5 OAJ11681.1 - 2.1 7.3 13.1 4.2 6.3 9.1 1.4 1 0 0 1 1 1 0 BUD22 TRAPP PF04051.11 OAJ11682.1 - 7.9e-34 116.3 0.0 9.4e-34 116.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component eIF3_N PF09440.5 OAJ11683.1 - 6.3e-40 136.4 2.2 7.9e-40 136.0 0.3 2.0 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 OAJ11683.1 - 9.4e-10 38.7 0.1 2e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.1 OAJ11683.1 - 0.0083 15.8 2.1 2 8.3 0.4 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ11683.1 - 0.81 9.7 4.1 3.5 7.7 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3628 PF12300.3 OAJ11683.1 - 5.5 6.9 22.8 11 6.0 15.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) GATA PF00320.22 OAJ11684.1 - 2.4e-12 45.9 12.4 1.4e-06 27.5 2.2 2.5 2 0 0 2 2 2 2 GATA zinc finger Zn-ribbon_8 PF09723.5 OAJ11684.1 - 0.029 14.3 0.5 4.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 OAJ11684.1 - 0.61 9.4 9.8 0.28 10.5 0.2 3.1 2 1 0 2 2 2 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 OAJ11684.1 - 2.8 7.8 8.2 2.4 8.0 0.2 3.3 2 1 1 3 3 3 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 OAJ11684.1 - 3.9 7.2 5.4 5.1 6.8 0.3 2.8 2 2 1 3 3 3 0 Putative transposase DNA-binding domain ALS_ss_C PF10369.4 OAJ11692.1 - 1.2e-20 72.9 0.0 3.1e-19 68.4 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 OAJ11692.1 - 2.5e-12 45.9 0.1 5e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 OAJ11692.1 - 7.3e-09 35.3 0.1 2.5e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 ACT domain Macoilin PF09726.4 OAJ11692.1 - 2.4 6.3 11.1 3.9 5.6 7.7 1.2 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_L5_C PF00673.16 OAJ11694.1 - 9.4e-21 73.3 0.0 1.5e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 OAJ11694.1 - 1.9e-19 69.2 0.1 5.2e-19 67.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Prefoldin_2 PF01920.15 OAJ11695.1 - 2.8e-22 78.4 14.3 3.5e-22 78.1 9.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit NPV_P10 PF05531.7 OAJ11695.1 - 8.2e-05 22.7 5.6 0.057 13.6 0.1 2.1 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein Lzipper-MIP1 PF14389.1 OAJ11695.1 - 0.0016 18.4 7.7 0.002 18.2 1.5 2.3 2 1 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 Uds1 PF15456.1 OAJ11695.1 - 0.012 15.5 7.7 0.015 15.2 4.9 1.6 1 1 0 1 1 1 0 Up-regulated During Septation Prefoldin_3 PF13758.1 OAJ11695.1 - 0.015 15.0 6.5 0.018 14.7 4.2 1.4 1 1 0 1 1 1 0 Prefoldin subunit DUF3166 PF11365.3 OAJ11695.1 - 0.024 15.1 3.2 4.5 7.7 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) MAP65_ASE1 PF03999.7 OAJ11695.1 - 0.026 13.1 4.6 0.031 12.8 3.2 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DASH_Dam1 PF08653.5 OAJ11695.1 - 0.049 13.3 2.0 4.7 7.0 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 BRE1 PF08647.6 OAJ11695.1 - 0.053 13.4 1.7 0.053 13.4 1.2 2.3 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase OmdA PF13376.1 OAJ11695.1 - 0.056 13.1 0.4 0.16 11.6 0.1 1.9 2 0 0 2 2 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Spore_YpjB PF09577.5 OAJ11695.1 - 0.071 12.6 3.9 0.088 12.3 2.7 1.1 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) DUF724 PF05266.9 OAJ11695.1 - 0.077 12.6 10.1 0.11 12.1 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FlxA PF14282.1 OAJ11695.1 - 0.13 12.1 14.4 0.22 11.4 1.0 2.2 2 0 0 2 2 2 0 FlxA-like protein AAA_27 PF13514.1 OAJ11695.1 - 0.14 9.8 11.9 0.15 9.6 8.3 1.0 1 0 0 1 1 1 0 AAA domain Fucose_iso_N2 PF07882.7 OAJ11695.1 - 0.14 11.7 2.0 0.15 11.6 1.4 1.1 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Vac_Fusion PF02346.11 OAJ11695.1 - 0.18 11.2 2.1 11 5.5 0.3 2.3 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Mnd1 PF03962.10 OAJ11695.1 - 0.18 11.4 13.4 0.4 10.3 3.9 2.0 1 1 1 2 2 2 0 Mnd1 family DUF2205 PF10224.4 OAJ11695.1 - 0.18 11.3 11.4 0.06 12.9 1.0 2.2 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Atg14 PF10186.4 OAJ11695.1 - 0.2 10.5 12.3 0.52 9.2 8.5 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 OAJ11695.1 - 0.21 11.4 14.0 0.14 12.0 3.2 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_MT_bd PF06657.8 OAJ11695.1 - 0.26 11.2 8.5 0.3 11.0 1.2 2.7 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 KxDL PF10241.4 OAJ11695.1 - 0.31 10.9 5.2 0.6 10.0 0.1 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein Nup54 PF13874.1 OAJ11695.1 - 0.32 10.6 11.5 0.75 9.4 2.2 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Macoilin PF09726.4 OAJ11695.1 - 0.33 9.1 13.3 0.38 8.9 9.2 1.0 1 0 0 1 1 1 0 Transmembrane protein PHTB1_C PF14728.1 OAJ11695.1 - 0.4 9.4 4.5 0.53 9.0 3.1 1.3 1 1 0 1 1 1 0 PTHB1 C-terminus Spc7 PF08317.6 OAJ11695.1 - 0.41 9.2 14.1 0.56 8.8 9.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein KMP11 PF03037.11 OAJ11695.1 - 0.44 11.1 4.7 0.8 10.3 2.4 1.9 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 APG6 PF04111.7 OAJ11695.1 - 0.45 9.5 15.0 0.16 11.0 5.6 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 LPP PF04728.8 OAJ11695.1 - 0.53 10.1 5.2 3.4 7.5 1.0 2.7 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Occludin_ELL PF07303.8 OAJ11695.1 - 0.59 10.9 7.9 5.2 7.8 1.7 2.2 1 1 1 2 2 2 0 Occludin homology domain HrpB7 PF09486.5 OAJ11695.1 - 0.72 9.7 8.5 6.6 6.6 0.4 2.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) LLC1 PF14945.1 OAJ11695.1 - 0.72 10.1 3.8 0.36 11.1 0.6 1.8 1 1 1 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Laminin_II PF06009.7 OAJ11695.1 - 0.73 9.5 11.2 0.26 11.0 1.0 2.1 1 1 0 2 2 2 0 Laminin Domain II SlyX PF04102.7 OAJ11695.1 - 0.76 10.1 11.1 0.085 13.2 0.9 2.5 2 1 0 2 2 2 0 SlyX Baculo_PEP_C PF04513.7 OAJ11695.1 - 0.77 9.5 6.7 1.8 8.4 0.4 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliD_C PF07195.7 OAJ11695.1 - 0.85 8.8 10.4 6.1 6.0 7.2 1.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus IncA PF04156.9 OAJ11695.1 - 0.94 9.0 16.2 5.7 6.4 11.3 1.9 1 1 0 1 1 1 0 IncA protein Med4 PF10018.4 OAJ11695.1 - 1.1 8.6 8.5 0.34 10.2 0.1 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF1664 PF07889.7 OAJ11695.1 - 1.3 8.8 9.2 1.6 8.5 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Sas10_Utp3 PF04000.10 OAJ11695.1 - 1.5 9.0 5.6 5.6 7.2 0.1 2.4 2 1 0 2 2 2 0 Sas10/Utp3/C1D family Fib_alpha PF08702.5 OAJ11695.1 - 1.8 8.6 11.8 15 5.7 7.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GrpE PF01025.14 OAJ11695.1 - 2.1 7.8 12.3 2.7 7.5 1.7 2.1 2 0 0 2 2 2 0 GrpE Phlebovirus_NSM PF07246.6 OAJ11695.1 - 2.2 7.3 7.0 3 6.9 4.9 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Peptidase_S46 PF10459.4 OAJ11695.1 - 2.3 6.5 9.0 2.8 6.2 6.2 1.0 1 0 0 1 1 1 0 Peptidase S46 Mto2_bdg PF12808.2 OAJ11695.1 - 2.4 8.3 10.6 11 6.2 0.3 3.4 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region AATF-Che1 PF13339.1 OAJ11695.1 - 2.5 8.2 10.1 12 6.1 7.0 1.9 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Med28 PF11594.3 OAJ11695.1 - 2.6 8.3 9.0 2.7 8.2 2.1 2.0 1 1 1 2 2 2 0 Mediator complex subunit 28 Dict-STAT-coil PF09267.5 OAJ11695.1 - 2.7 8.2 8.0 2 8.6 1.9 2.2 1 1 0 2 2 2 0 Dictyostelium STAT, coiled coil Seryl_tRNA_N PF02403.17 OAJ11695.1 - 2.7 8.0 13.8 48 4.0 9.5 2.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.6 OAJ11695.1 - 2.8 7.6 14.6 11 5.8 10.1 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.3 OAJ11695.1 - 2.9 7.6 14.9 4.5 7.0 2.6 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding SKIP_SNW PF02731.10 OAJ11695.1 - 3.3 7.1 9.0 2.7 7.4 1.4 2.1 2 0 0 2 2 2 0 SKIP/SNW domain Allexi_40kDa PF05549.6 OAJ11695.1 - 3.4 6.8 6.5 1.9 7.6 1.6 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF3106 PF11304.3 OAJ11695.1 - 3.4 8.1 8.4 1 9.8 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) bZIP_1 PF00170.16 OAJ11695.1 - 3.4 7.6 11.1 8.3 6.4 0.8 3.0 2 1 1 3 3 3 0 bZIP transcription factor ORF6C PF10552.4 OAJ11695.1 - 3.4 7.4 8.4 1.1 8.9 2.0 2.3 1 1 1 2 2 2 0 ORF6C domain CENP-Q PF13094.1 OAJ11695.1 - 4.6 7.2 16.5 3.5 7.6 1.8 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc24 PF08286.6 OAJ11695.1 - 5.2 6.7 15.8 12 5.5 2.9 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF948 PF06103.6 OAJ11695.1 - 5.4 6.9 6.8 2.1 8.2 0.8 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) YgaB PF14182.1 OAJ11695.1 - 5.4 7.3 13.3 0.44 10.8 2.4 2.4 2 1 0 2 2 2 0 YgaB-like protein Tropomyosin_1 PF12718.2 OAJ11695.1 - 5.5 6.8 18.3 99 2.7 12.7 2.3 1 1 0 1 1 1 0 Tropomyosin like DUF607 PF04678.8 OAJ11695.1 - 5.5 6.8 7.2 4.4 7.1 2.0 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Prefoldin PF02996.12 OAJ11695.1 - 5.5 6.6 14.9 0.87 9.2 3.1 2.7 2 1 1 3 3 3 0 Prefoldin subunit Rootletin PF15035.1 OAJ11695.1 - 5.7 6.8 14.1 3.4 7.6 5.9 2.5 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion ADIP PF11559.3 OAJ11695.1 - 6.3 6.6 16.4 4.6 7.1 2.7 2.2 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 OAJ11695.1 - 6.7 7.1 12.9 10 6.5 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 OAJ11695.1 - 6.8 5.0 14.3 12 4.2 9.9 1.4 1 1 0 1 1 1 0 AAA domain Kinetocho_Slk19 PF12709.2 OAJ11695.1 - 8.2 6.5 13.8 5.2 7.2 1.5 3.1 2 2 2 4 4 3 0 Central kinetochore-associated DUF641 PF04859.7 OAJ11695.1 - 8.5 6.1 13.0 2.8 7.7 3.0 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TPR_MLP1_2 PF07926.7 OAJ11695.1 - 9 6.0 17.5 1.6e+02 1.9 11.0 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 OAJ11695.1 - 9.7 5.6 17.1 21 4.5 3.8 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 FYVE PF01363.16 OAJ11696.1 - 9.8e-19 67.0 0.0 2.2e-18 65.9 0.0 1.6 1 1 0 1 1 1 1 FYVE zinc finger TerY-C PF15616.1 OAJ11696.1 - 0.0076 16.1 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 TerY-C metal binding domain zf-DHHC PF01529.15 OAJ11696.1 - 0.11 11.9 0.9 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase DZR PF12773.2 OAJ11696.1 - 0.79 9.5 4.1 1.1 9.1 1.1 2.1 2 0 0 2 2 2 0 Double zinc ribbon UPF0547 PF10571.4 OAJ11696.1 - 6.8 6.4 6.3 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 UQ_con PF00179.21 OAJ11697.1 - 2.3e-49 166.4 0.0 3e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ11697.1 - 3.1e-07 30.2 0.0 8.3e-07 28.8 0.0 1.6 1 1 1 2 2 2 1 Prokaryotic E2 family B Acetyltransf_1 PF00583.19 OAJ11698.1 - 1.3e-14 53.9 0.1 1.9e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAJ11698.1 - 0.00022 21.3 0.0 0.00026 21.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ11698.1 - 0.00049 19.8 0.0 0.00076 19.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 OAJ11698.1 - 0.00095 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAJ11698.1 - 0.0048 16.7 0.2 0.0082 15.9 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAJ11698.1 - 0.036 14.0 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SspB PF04386.8 OAJ11698.1 - 0.058 13.0 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 Stringent starvation protein B Thiolase_C PF02803.13 OAJ11709.1 - 1.9e-11 43.4 0.7 1.4e-10 40.6 0.2 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 OAJ11709.1 - 2.2e-07 30.1 4.3 5.9e-07 28.7 0.2 2.9 2 1 1 3 3 3 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 OAJ11709.1 - 0.0031 17.1 1.2 0.058 13.0 0.3 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 OAJ11709.1 - 0.011 15.1 4.6 0.15 11.5 1.0 2.4 1 1 1 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 OAJ11709.1 - 0.028 14.2 1.3 0.13 12.1 0.5 2.5 2 1 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain GST_N PF02798.15 OAJ11710.1 - 5.5e-13 48.8 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 OAJ11710.1 - 1.5e-10 41.1 0.0 2.6e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ11710.1 - 2.1e-10 40.4 0.0 3.8e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ11710.1 - 4.4e-10 39.4 0.0 6.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ11710.1 - 2.7e-08 33.5 0.1 4.9e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ11710.1 - 3.4e-06 27.4 0.2 5.6e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Hexokinase_1 PF00349.16 OAJ11711.1 - 7.3e-64 214.8 0.0 1e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 OAJ11711.1 - 2e-61 207.2 0.3 3.8e-45 153.9 0.0 2.1 2 0 0 2 2 2 2 Hexokinase MCM PF00493.18 OAJ11712.1 - 9.5e-132 438.7 0.0 3.2e-131 437.0 0.0 1.7 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 OAJ11712.1 - 1e-25 90.5 0.0 2.2e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.9 OAJ11712.1 - 1.3e-07 31.4 0.0 2.6e-05 23.9 0.0 2.6 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 OAJ11712.1 - 7.2e-07 28.5 0.0 5e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Mg_chelatase_2 PF13335.1 OAJ11712.1 - 0.0031 17.8 0.2 0.0086 16.4 0.1 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 OAJ11712.1 - 0.03 13.9 0.0 0.088 12.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-BED PF02892.10 OAJ11723.1 - 0.0019 17.9 1.1 0.0045 16.7 0.8 1.6 1 0 0 1 1 1 1 BED zinc finger RVT_1 PF00078.22 OAJ11739.1 - 5e-22 78.3 0.0 8.9e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.7 OAJ11739.1 - 1.9 6.2 5.0 2.8 5.7 3.4 1.1 1 0 0 1 1 1 0 Nop14-like family Glycoprotein_B PF00606.13 OAJ11746.1 - 0.061 11.3 0.2 0.073 11.1 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B DUF3685 PF12452.3 OAJ11746.1 - 0.097 11.8 0.8 0.18 10.9 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3685) Baculo_PEP_C PF04513.7 OAJ11747.1 - 4e-05 23.4 11.1 0.0013 18.5 0.3 3.5 2 2 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 OAJ11747.1 - 0.032 13.6 3.0 1.5 8.2 0.2 2.2 2 0 0 2 2 2 0 Intermediate filament protein AAA_13 PF13166.1 OAJ11747.1 - 0.066 11.6 4.1 0.12 10.7 2.3 1.7 1 1 0 1 1 1 0 AAA domain PIN_2 PF10130.4 OAJ11747.1 - 0.15 12.1 1.2 1.6 8.8 0.1 2.5 2 0 0 2 2 2 0 PIN domain Syntaxin PF00804.20 OAJ11747.1 - 0.16 12.1 6.8 0.61 10.2 0.0 3.2 3 1 0 3 3 3 0 Syntaxin Syntaxin-6_N PF09177.6 OAJ11747.1 - 0.29 11.5 4.5 6 7.3 0.7 2.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Sas10_Utp3 PF04000.10 OAJ11747.1 - 0.54 10.4 5.1 0.92 9.7 0.1 3.6 3 1 0 3 3 3 0 Sas10/Utp3/C1D family DUF4407 PF14362.1 OAJ11747.1 - 0.54 9.1 8.2 3.5 6.4 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.8 OAJ11747.1 - 1.3 9.8 4.8 1.3 9.8 1.0 2.3 2 0 0 2 2 2 0 Occludin homology domain Nup54 PF13874.1 OAJ11747.1 - 1.3 8.7 5.6 24 4.5 0.2 3.2 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 Fzo_mitofusin PF04799.8 OAJ11747.1 - 2.2 7.6 6.0 4.4 6.6 1.4 2.4 2 0 0 2 2 2 0 fzo-like conserved region Seryl_tRNA_N PF02403.17 OAJ11747.1 - 3.6 7.6 8.9 7 6.7 0.4 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain WXG100 PF06013.7 OAJ11747.1 - 7 6.7 9.7 20 5.3 0.5 3.7 4 1 0 4 4 4 0 Proteins of 100 residues with WXG Sugar_tr PF00083.19 OAJ11748.1 - 5.6e-34 117.4 23.7 2.8e-33 115.2 16.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ11748.1 - 1.3e-16 60.2 39.4 2.7e-12 46.1 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 OAJ11748.1 - 0.00058 18.6 0.8 0.37 9.4 0.0 2.4 2 0 0 2 2 2 2 BT1 family DUF2256 PF10013.4 OAJ11749.1 - 5.3e-12 45.2 4.2 9.9e-12 44.4 2.9 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) DNA_pol_viral_C PF00336.13 OAJ11750.1 - 0.048 12.9 0.1 0.098 11.9 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Phage_integrase PF00589.17 OAJ11751.1 - 6.8e-05 22.6 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family MULE PF10551.4 OAJ11761.1 - 5.8e-09 35.9 0.0 1.5e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 OAJ11761.1 - 2.1e-05 23.8 0.2 4.8e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger DDE_Tnp_IS240 PF13610.1 OAJ11761.1 - 0.0062 16.4 0.5 2.9 7.8 0.0 2.9 3 0 0 3 3 3 2 DDE domain DUF3860 PF12976.2 OAJ11761.1 - 0.03 14.1 0.1 0.085 12.6 0.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) G-alpha PF00503.15 OAJ11762.1 - 4.5e-79 265.9 0.0 4.2e-52 177.1 0.0 3.2 3 0 0 3 3 3 3 G-protein alpha subunit Arf PF00025.16 OAJ11762.1 - 7e-10 38.4 0.0 1.1e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.1 OAJ11762.1 - 0.0019 18.3 0.0 0.038 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 OAJ11762.1 - 0.0056 17.1 0.0 0.036 14.5 0.0 2.3 3 0 0 3 3 3 1 Miro-like protein Zeta_toxin PF06414.7 OAJ11762.1 - 0.006 15.7 0.0 0.027 13.5 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.22 OAJ11762.1 - 0.006 16.8 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 OAJ11762.1 - 0.0087 15.5 0.0 0.16 11.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 OAJ11762.1 - 0.019 14.4 0.0 0.32 10.4 0.0 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 OAJ11762.1 - 0.022 14.4 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 OAJ11762.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArfGap PF01412.13 OAJ11764.1 - 6.2e-40 135.6 1.4 8.9e-40 135.1 0.9 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Spo12 PF05032.7 OAJ11775.1 - 2.2e-09 36.7 4.6 4.2e-09 35.8 3.2 1.5 1 0 0 1 1 1 1 Spo12 family SnoaL_2 PF12680.2 OAJ11775.1 - 0.001 19.4 0.0 0.0017 18.7 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain ubiquitin PF00240.18 OAJ11776.1 - 2e-24 84.7 0.1 2.2e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 OAJ11776.1 - 1.6e-15 56.4 0.0 1.8e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAJ11776.1 - 0.0003 20.9 0.0 0.00038 20.6 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-like domain TFIIB PF00382.14 OAJ11777.1 - 2.5e-26 91.2 0.0 1.1e-17 63.5 0.0 2.8 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 OAJ11777.1 - 1.7e-22 79.4 4.6 1.7e-22 79.4 3.2 4.6 3 1 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 OAJ11777.1 - 5.4e-07 28.8 1.1 1.1e-06 27.8 0.8 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 OAJ11777.1 - 3.4e-06 26.6 0.0 0.11 12.0 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Ribosomal_S27e PF01667.12 OAJ11777.1 - 0.091 12.3 1.2 0.17 11.4 0.8 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 DNA_RNApol_7kD PF03604.8 OAJ11777.1 - 0.24 10.8 4.2 0.49 9.9 2.9 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Cpn60_TCP1 PF00118.19 OAJ11778.1 - 1.9e-143 478.5 0.2 2.2e-143 478.4 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.27 OAJ11779.1 - 1.4e-25 88.1 1.2 5.3e-07 29.2 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat PD40 PF07676.7 OAJ11779.1 - 0.063 12.9 0.7 0.17 11.5 0.1 2.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Methyltransf_31 PF13847.1 OAJ11780.1 - 1.2e-12 47.7 0.0 1.7e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ11780.1 - 1.2e-12 48.4 0.0 1.9e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ11780.1 - 4.7e-06 27.0 0.0 8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ11780.1 - 8.2e-06 25.8 0.0 1.9e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 OAJ11780.1 - 4.9e-05 23.0 0.0 6.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ11780.1 - 8.8e-05 22.8 0.0 0.00017 21.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ11780.1 - 0.00025 21.4 0.0 0.004 17.6 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ11780.1 - 0.00053 19.7 0.0 0.00098 18.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 OAJ11780.1 - 0.12 11.6 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Las1 PF04031.8 OAJ11781.1 - 5.5e-44 149.5 0.0 7.4e-44 149.1 0.0 1.1 1 0 0 1 1 1 1 Las1-like zf-H2C2_2 PF13465.1 OAJ11791.1 - 8.2e-06 25.8 3.3 8.2e-06 25.8 2.3 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ11791.1 - 0.00041 20.5 20.5 0.0012 19.0 1.4 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ11791.1 - 0.0044 17.2 18.7 0.0067 16.6 1.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger Opi1 PF08618.5 OAJ11792.1 - 5e-69 233.2 5.6 5e-69 233.2 3.9 4.4 5 1 0 6 6 6 1 Transcription factor Opi1 Helicase_C_2 PF13307.1 OAJ11811.1 - 8.8e-38 129.8 0.0 1.7e-37 128.9 0.0 1.5 2 0 0 2 2 2 1 Helicase C-terminal domain NADH_dehy_S2_C PF06444.6 OAJ11811.1 - 0.21 11.9 1.8 0.52 10.6 0.0 2.3 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 C-terminus Sen15 PF09631.5 OAJ11812.1 - 4.3e-12 46.1 0.0 2.3e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 Sen15 protein DUF2392 PF10288.4 OAJ11813.1 - 2e-15 57.0 0.0 3.3e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) MIP PF00230.15 OAJ11814.1 - 3.7e-36 124.7 11.9 4.9e-36 124.3 8.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein RCC1 PF00415.13 OAJ11815.1 - 1.4e-19 69.9 14.8 5.8e-05 23.2 0.0 7.0 5 2 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ11815.1 - 1.1e-18 66.3 24.2 7.4e-11 41.3 0.3 6.0 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 OAJ11816.1 - 4.5e-13 48.6 3.7 1e-12 47.5 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ11816.1 - 3.6e-09 36.0 2.1 8.5e-09 34.8 0.0 2.2 2 0 0 2 2 2 1 F-box domain RXT2_N PF08595.6 OAJ11816.1 - 0.0016 18.2 1.9 2.2 8.0 1.9 2.1 1 1 1 2 2 2 2 RXT2-like, N-terminal Osteopontin PF00865.13 OAJ11816.1 - 0.08 12.1 2.1 0.11 11.7 1.4 1.1 1 0 0 1 1 1 0 Osteopontin DASH_Dam1 PF08653.5 OAJ11817.1 - 1.8e-20 72.4 0.5 3.5e-20 71.5 0.3 1.5 1 0 0 1 1 1 1 DASH complex subunit Dam1 PCI PF01399.22 OAJ11826.1 - 9.2e-20 70.9 0.1 3.5e-19 69.0 0.0 2.1 1 0 0 1 1 1 1 PCI domain TPR_16 PF13432.1 OAJ11826.1 - 0.00011 22.8 17.7 0.091 13.4 4.4 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ11826.1 - 0.0017 17.9 9.8 0.21 11.2 1.2 3.7 3 0 0 3 3 3 2 TPR repeat DUF627 PF04781.7 OAJ11826.1 - 0.004 16.7 1.5 2.8 7.5 0.1 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF627) TPR_7 PF13176.1 OAJ11826.1 - 0.055 13.2 1.0 6.2 6.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ11826.1 - 0.089 13.1 13.9 0.24 11.7 1.2 4.6 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.4 OAJ11826.1 - 0.11 12.4 17.7 1.2 9.0 5.7 3.7 2 1 1 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 OAJ11826.1 - 0.11 12.5 4.9 4.4 7.5 0.1 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.1 OAJ11826.1 - 0.15 12.2 6.2 0.35 11.0 0.5 3.6 3 1 2 5 5 5 0 Alkyl sulfatase dimerisation TPR_6 PF13174.1 OAJ11826.1 - 0.15 12.5 8.4 13 6.5 0.2 5.1 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ11826.1 - 0.34 11.6 16.1 0.73 10.6 1.4 5.2 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ11826.1 - 6.6 6.9 13.1 54 4.0 0.1 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat Pribosyltran PF00156.22 OAJ11827.1 - 7e-17 61.3 0.2 9.8e-17 60.8 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 OAJ11827.1 - 0.0039 16.4 0.0 0.0052 16.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase An_peroxidase PF03098.10 OAJ11828.1 - 0.00018 20.0 0.2 0.00029 19.3 0.1 1.3 1 1 0 1 1 1 1 Animal haem peroxidase NAD_binding_11 PF14833.1 OAJ11829.1 - 2.3e-07 30.8 0.1 3.8e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase TAF4 PF05236.9 OAJ11830.1 - 0.17 11.1 1.4 0.18 11.0 1.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family SecY PF00344.15 OAJ11831.1 - 6e-22 78.0 0.0 4.8e-19 68.4 0.0 2.3 2 0 0 2 2 2 2 SecY translocase Aminotran_1_2 PF00155.16 OAJ11831.1 - 5.3e-17 61.8 0.0 2.9e-15 56.0 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II RPN7 PF10602.4 OAJ11832.1 - 2e-52 177.1 1.6 2.8e-52 176.6 1.1 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 OAJ11832.1 - 3.1e-14 53.1 0.0 7.4e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 PCI domain SAC3_GANP PF03399.11 OAJ11832.1 - 0.0098 15.4 0.7 0.015 14.8 0.1 1.6 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Selenoprotein_S PF06936.6 OAJ11832.1 - 0.029 13.9 0.3 0.79 9.2 0.2 2.2 2 0 0 2 2 2 0 Selenoprotein S (SelS) RasGEF PF00617.14 OAJ11841.1 - 3.5e-40 137.7 0.1 5.6e-40 137.0 0.1 1.2 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 OAJ11841.1 - 4e-07 30.0 0.0 8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 OAJ11841.1 - 6.3e-05 23.4 0.0 0.00013 22.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 OAJ11841.1 - 0.00058 19.2 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.16 OAJ11841.1 - 0.03 13.5 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Nop14 PF04147.7 OAJ11841.1 - 0.48 8.2 3.6 0.79 7.5 2.5 1.2 1 0 0 1 1 1 0 Nop14-like family Aminotran_1_2 PF00155.16 OAJ11842.1 - 2.9e-36 125.1 0.0 5.7e-36 124.2 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAJ11842.1 - 0.0031 16.7 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.2 OAJ11842.1 - 0.031 12.8 0.0 0.064 11.7 0.0 1.4 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Dimer_Tnp_hAT PF05699.9 OAJ11852.1 - 1.8e-14 53.0 0.0 4.5e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.20 OAJ11853.1 - 4.9e-39 134.0 0.0 7.5e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ11853.1 - 2.8e-20 72.5 0.0 4.2e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.22 OAJ11853.1 - 4.6e-17 62.0 0.0 8.7e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ11853.1 - 8.3e-15 54.9 0.0 1.5e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RTC4 PF14474.1 OAJ11853.1 - 0.0059 16.5 0.0 0.015 15.2 0.0 1.6 1 1 0 1 1 1 1 RTC4-like domain Pox_ser-thr_kin PF05445.6 OAJ11853.1 - 0.044 12.5 0.0 0.067 11.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 OAJ11853.1 - 0.24 10.4 0.0 0.75 8.8 0.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Asp_protease_2 PF13650.1 OAJ11854.1 - 0.00035 21.0 0.0 0.00079 19.8 0.0 1.7 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ11854.1 - 0.011 15.5 0.0 0.027 14.3 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease DUF2505 PF10698.4 OAJ11856.1 - 0.099 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) OTT_1508_deam PF14441.1 OAJ11866.1 - 7.7e-06 25.7 0.5 3e-05 23.8 0.4 1.9 1 1 0 1 1 1 1 OTT_1508-like deaminase MafB19-deam PF14437.1 OAJ11866.1 - 0.002 17.7 0.1 0.0035 16.9 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.17 OAJ11866.1 - 0.0021 17.6 1.3 0.0051 16.4 0.1 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region HATPase_c_2 PF13581.1 OAJ11866.1 - 0.078 12.7 0.2 0.25 11.1 0.1 1.9 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain zf-MYND PF01753.13 OAJ11867.1 - 2e-06 27.5 15.6 4.1e-06 26.5 10.8 1.6 1 0 0 1 1 1 1 MYND finger ABC2_membrane_4 PF12730.2 OAJ11868.1 - 0.0069 15.5 5.7 0.012 14.8 0.1 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF1129 PF06570.6 OAJ11868.1 - 1.2 8.4 5.4 11 5.2 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4231 PF14015.1 OAJ11868.1 - 1.9 8.4 16.6 2.7 8.0 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF1628 PF07790.6 OAJ11868.1 - 2.5 8.8 10.5 6.6 7.5 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1628) PrmA PF06325.8 OAJ11876.1 - 1.1e-09 37.9 0.0 1.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 OAJ11876.1 - 4.5e-06 26.3 0.0 8.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ11876.1 - 1.3e-05 25.7 0.0 2.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ11876.1 - 1.6e-05 24.8 0.0 5.8e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ11876.1 - 2.6e-05 24.0 0.0 5.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ11876.1 - 0.00032 20.1 0.0 0.00069 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 OAJ11876.1 - 0.00071 20.0 0.0 0.0017 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ11876.1 - 0.0012 19.1 0.0 0.003 17.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 OAJ11876.1 - 0.0089 14.9 0.0 0.016 14.1 0.0 1.5 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.6 OAJ11876.1 - 0.044 12.4 0.0 0.072 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.10 OAJ11876.1 - 0.053 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_12 PF08242.7 OAJ11876.1 - 0.061 13.8 1.3 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain SDA1 PF05285.7 OAJ11876.1 - 0.22 10.7 4.9 0.35 10.1 3.4 1.3 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.4 OAJ11876.1 - 8.9 4.9 16.5 22 3.6 11.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nt_Gln_amidase PF09764.4 OAJ11877.1 - 3.5e-26 91.6 0.9 2.3e-08 33.5 0.0 4.8 4 1 0 4 4 4 4 N-terminal glutamine amidase NAD_binding_10 PF13460.1 OAJ11878.1 - 6.7e-18 65.3 0.2 2.1e-17 63.7 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 OAJ11878.1 - 9e-11 41.4 0.0 1.2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 OAJ11878.1 - 2.1e-10 40.4 0.0 4.8e-10 39.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAJ11878.1 - 2.5e-10 39.5 0.0 6.7e-10 38.1 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 OAJ11878.1 - 3.7e-08 32.6 0.0 4.2e-06 25.8 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 OAJ11878.1 - 8e-08 31.5 0.2 0.0014 17.6 0.1 3.0 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 OAJ11878.1 - 0.0023 16.9 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 OAJ11878.1 - 0.0025 17.7 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAJ11878.1 - 0.015 14.9 0.0 0.22 11.1 0.0 2.4 2 0 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.10 OAJ11878.1 - 0.026 13.4 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Arginase PF00491.16 OAJ11879.1 - 3.7e-74 249.5 0.0 4.3e-74 249.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family Ank_2 PF12796.2 OAJ11885.1 - 7.5e-13 48.6 0.0 6.5e-12 45.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ11885.1 - 2.5e-11 42.7 0.0 0.025 14.3 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 OAJ11885.1 - 1.6e-08 34.8 0.3 0.00048 20.5 0.0 4.3 3 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ11885.1 - 2e-06 27.8 0.0 0.068 13.4 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ11885.1 - 3.3e-05 23.6 0.0 1.2 9.5 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat RVP PF00077.15 OAJ11885.1 - 0.17 11.8 0.0 7.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease LysM PF01476.15 OAJ11886.1 - 5.8e-53 176.5 11.2 1.9e-15 56.4 0.0 6.6 6 0 0 6 6 6 6 LysM domain EF-hand_6 PF13405.1 OAJ11886.1 - 1.3e-08 34.0 0.1 0.0014 18.3 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 OAJ11886.1 - 4.4e-08 31.8 0.1 0.0029 16.7 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 OAJ11886.1 - 2e-06 26.8 1.8 0.0069 15.6 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 OAJ11886.1 - 2.7e-05 24.2 0.0 0.38 10.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 OAJ11886.1 - 0.02 14.5 0.2 0.31 10.6 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair Glyco_hydro_18 PF00704.23 OAJ11887.1 - 2.2e-82 277.2 3.8 2.7e-82 276.9 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HRM PF02793.17 OAJ11887.1 - 0.0011 18.9 0.2 0.0028 17.6 0.2 1.7 1 0 0 1 1 1 1 Hormone receptor domain Sushi PF00084.15 OAJ11887.1 - 0.021 15.1 0.2 0.052 13.8 0.2 1.7 1 0 0 1 1 1 0 Sushi domain (SCR repeat) HSP70 PF00012.15 OAJ11892.1 - 1.4e-30 105.8 0.1 1.7e-30 105.5 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MmgE_PrpD PF03972.9 OAJ11894.1 - 2.9e-92 309.1 4.6 2.7e-52 177.4 0.3 2.8 1 1 1 2 2 2 2 MmgE/PrpD family GATA PF00320.22 OAJ11905.1 - 1.9e-15 55.8 6.0 4.6e-15 54.6 4.2 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 OAJ11905.1 - 0.0027 17.7 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold Pyr_redox_3 PF13738.1 OAJ11906.1 - 3.3e-22 79.5 0.1 2.2e-21 76.8 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAJ11906.1 - 3.3e-21 75.0 0.0 9.2e-21 73.6 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 OAJ11906.1 - 3.6e-11 43.3 1.8 3.5e-06 27.0 0.2 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ11906.1 - 7.2e-10 38.3 0.4 4.5e-07 29.1 0.0 2.8 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAJ11906.1 - 2.5e-09 37.0 1.1 1.3e-07 31.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ11906.1 - 6.1e-08 31.9 0.9 4.3e-06 25.8 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAJ11906.1 - 1.2e-05 25.5 3.3 0.04 14.3 0.4 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ11906.1 - 1.2e-05 25.1 5.3 0.0033 17.1 0.1 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding HI0933_like PF03486.9 OAJ11906.1 - 3.2e-05 22.6 0.2 0.03 12.7 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein AlaDh_PNT_C PF01262.16 OAJ11906.1 - 0.00021 20.9 1.3 0.048 13.2 0.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 OAJ11906.1 - 0.00027 20.1 3.1 0.041 12.9 0.2 2.5 3 0 0 3 3 3 2 Thi4 family Shikimate_DH PF01488.15 OAJ11906.1 - 0.00041 20.4 0.2 0.45 10.6 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 OAJ11906.1 - 0.00059 20.0 0.0 0.15 12.3 0.0 2.6 3 0 0 3 3 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 OAJ11906.1 - 0.00095 18.8 0.4 0.00095 18.8 0.3 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 OAJ11906.1 - 0.018 14.4 0.8 0.018 14.4 0.6 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 OAJ11906.1 - 0.045 12.6 2.5 2.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 OAJ11906.1 - 0.069 12.1 1.6 0.53 9.2 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 OAJ11906.1 - 0.075 12.0 0.1 0.79 8.7 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ11906.1 - 0.086 11.6 7.0 0.057 12.2 0.3 2.4 3 0 0 3 3 3 0 FAD binding domain LRR_4 PF12799.2 OAJ11907.1 - 2.3e-18 65.3 18.8 1.4e-07 30.9 4.7 5.6 3 2 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ11907.1 - 3e-18 65.2 15.5 4.2e-08 32.8 6.9 4.1 3 1 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 OAJ11907.1 - 8.1e-09 34.3 16.5 0.93 9.7 0.6 7.6 6 1 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 OAJ11907.1 - 2.8e-07 29.9 19.3 1.3 9.2 0.4 7.5 6 1 1 7 7 7 3 Leucine Rich repeat zf-CCCH PF00642.19 OAJ11907.1 - 4.2e-06 26.3 7.2 0.0027 17.3 0.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_7 PF13504.1 OAJ11907.1 - 0.0024 17.7 20.7 5.8 7.5 0.1 7.4 6 1 1 7 7 7 2 Leucine rich repeat DASH_Hsk3 PF08227.6 OAJ11918.1 - 0.026 14.7 0.1 0.077 13.2 0.1 1.8 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like UBN2_2 PF14227.1 OAJ11920.1 - 3.3e-12 46.0 0.0 6.1e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ11920.1 - 3.1e-08 33.4 0.0 4.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAJ11920.1 - 4.3e-05 23.0 0.9 7.3e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 GAG-pre-integrase domain DUF4219 PF13961.1 OAJ11920.1 - 8.5e-05 21.8 0.1 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) zf-CCHC PF00098.18 OAJ11920.1 - 0.0057 16.5 4.7 0.014 15.3 3.2 1.7 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.15 OAJ11920.1 - 0.019 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease API5 PF05918.6 OAJ11920.1 - 0.055 11.9 0.7 0.091 11.2 0.5 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-CCHC_2 PF13696.1 OAJ11920.1 - 0.14 11.6 3.3 0.3 10.6 2.3 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.9 OAJ11921.1 - 5.9e-76 254.6 0.0 7.6e-76 254.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PMT PF02366.13 OAJ11922.1 - 1.4e-06 27.8 6.6 0.0015 17.9 0.5 2.5 3 0 0 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase Ycf9 PF01737.12 OAJ11922.1 - 0.1 12.0 0.0 0.1 12.0 0.0 2.3 2 1 0 2 2 2 0 YCF9 RNA_pol_Rpb4 PF03874.11 OAJ11929.1 - 5.1e-13 49.0 0.1 7.2e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF1548 PF07579.6 OAJ11929.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) BRCT PF00533.21 OAJ11930.1 - 1.1e-09 38.2 0.3 7.5e-09 35.6 0.1 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 OAJ11930.1 - 0.00051 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain DCX PF03607.12 OAJ11930.1 - 0.035 13.6 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 Doublecortin TGF_beta_GS PF08515.7 OAJ11930.1 - 0.09 12.1 0.9 0.27 10.5 0.6 1.8 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif adh_short PF00106.20 OAJ11931.1 - 1.1e-14 54.7 0.8 2e-14 53.8 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAJ11931.1 - 1.3e-08 34.7 0.1 2.6e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ11931.1 - 0.0001 22.1 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 OAJ11931.1 - 0.051 12.4 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Na_Ca_ex PF01699.19 OAJ11933.1 - 8.5e-43 145.3 31.5 2.2e-21 75.9 6.7 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3742 PF12553.3 OAJ11933.1 - 0.53 10.7 2.8 13 6.3 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3742) PseudoU_synth_1 PF01416.15 OAJ11942.1 - 1e-16 61.2 0.0 1.1e-07 32.1 0.0 3.0 2 1 0 2 2 2 2 tRNA pseudouridine synthase GST_N_3 PF13417.1 OAJ11943.1 - 9.3e-07 28.9 0.0 2.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ11943.1 - 0.014 15.3 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain F-box PF00646.28 OAJ11944.1 - 0.078 12.6 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 F-box domain CPSase_L_D2 PF02786.12 OAJ11946.1 - 3.4e-49 167.0 0.0 5.3e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Carboxyl_trans PF01039.17 OAJ11946.1 - 6.2e-46 156.7 0.1 1.3e-41 142.4 0.0 2.1 2 0 0 2 2 2 2 Carboxyl transferase domain Biotin_carb_C PF02785.14 OAJ11946.1 - 2.9e-21 75.4 0.0 6.8e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 OAJ11946.1 - 1.3e-19 70.2 0.0 3.2e-18 65.8 0.0 3.0 3 0 0 3 3 3 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_lipoyl PF00364.17 OAJ11946.1 - 1.5e-17 62.9 0.1 3.2e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 OAJ11946.1 - 3.9e-11 43.0 0.1 9.3e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 OAJ11946.1 - 8.8e-11 41.3 0.3 0.00037 20.0 0.0 3.0 1 1 1 2 2 2 2 Biotin-lipoyl like ATPgrasp_Ter PF15632.1 OAJ11946.1 - 7.9e-06 24.8 0.0 8.2e-05 21.4 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon HlyD_2 PF12700.2 OAJ11946.1 - 2.3e-05 23.7 0.8 0.021 13.9 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 OAJ11946.1 - 4.9e-05 22.7 5.4 0.0016 17.8 1.9 2.3 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 OAJ11946.1 - 0.003 17.8 0.2 2.2 8.6 0.0 2.9 3 0 0 3 3 2 1 HlyD family secretion protein RnfC_N PF13375.1 OAJ11946.1 - 0.0044 16.7 0.1 0.016 14.9 0.1 1.9 2 0 0 2 2 1 1 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.4 OAJ11946.1 - 0.0055 16.4 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2118) MdcE PF06833.6 OAJ11946.1 - 0.006 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) RVT_1 PF00078.22 OAJ11956.1 - 1e-19 70.7 0.0 1.7e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MULE PF10551.4 OAJ11958.1 - 1.3e-08 34.8 0.0 4.6e-08 33.1 0.0 2.0 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 OAJ11958.1 - 0.017 14.5 0.6 0.017 14.5 0.4 2.5 2 0 0 2 2 2 0 SWIM zinc finger DDE_Tnp_IS240 PF13610.1 OAJ11958.1 - 0.071 13.0 0.0 22 5.0 0.0 3.0 3 0 0 3 3 3 0 DDE domain DUF2242 PF10001.4 OAJ11958.1 - 7.1 6.5 6.2 0.55 10.0 0.1 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2242) F-box-like PF12937.2 OAJ11967.1 - 0.0022 17.6 0.1 0.0078 15.9 0.0 2.0 2 0 0 2 2 2 1 F-box-like Peptidase_M16 PF00675.15 OAJ11968.1 - 8.1e-40 135.9 0.0 1.6e-39 135.0 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 OAJ11968.1 - 3.1e-38 131.3 0.0 8.4e-38 129.8 0.0 1.8 1 1 0 1 1 1 1 Peptidase M16 inactive domain PH_4 PF15404.1 OAJ11971.1 - 9.1e-30 103.5 0.1 3.6e-29 101.6 0.0 2.1 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 OAJ11971.1 - 0.0019 18.3 0.0 8.4 6.6 0.0 3.9 4 0 0 4 4 4 2 PH domain DUF4642 PF15484.1 OAJ11982.1 - 0.053 13.4 0.3 0.08 12.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) BUD22 PF09073.5 OAJ11982.1 - 0.095 11.7 4.5 0.11 11.5 3.1 1.1 1 0 0 1 1 1 0 BUD22 2OG-FeII_Oxy_2 PF13532.1 OAJ11983.1 - 3.4e-15 56.4 0.0 9.5e-15 54.9 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ11983.1 - 0.0042 17.3 0.0 0.021 15.1 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Serglycin PF04360.7 OAJ11983.1 - 0.42 10.3 3.4 1.2 8.8 2.1 1.9 2 0 0 2 2 2 0 Serglycin Drf_GBD PF06371.8 OAJ11985.1 - 1.6e-13 50.4 0.0 2.7e-12 46.4 0.0 2.4 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain DBR1 PF05011.8 OAJ11987.1 - 3.8e-12 46.3 0.0 4.4e-11 42.8 0.0 2.4 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 OAJ11987.1 - 4.9e-05 22.8 1.2 9.4e-05 21.8 0.8 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ATP-synt_DE_N PF02823.11 OAJ11988.1 - 3.8e-19 68.2 0.0 5.3e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Cas_Csa5 PF09702.5 OAJ11988.1 - 0.12 12.4 0.6 0.65 10.1 0.1 2.2 2 1 1 3 3 3 0 CRISPR-associated protein (Cas_Csa5) Thg1 PF04446.7 OAJ11997.1 - 5.8e-44 148.9 0.0 8.3e-44 148.4 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 OAJ11997.1 - 2.6e-43 146.5 0.0 4.1e-43 145.9 0.0 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain CPSF73-100_C PF11718.3 OAJ11999.1 - 8.1e-47 159.3 2.8 8.4e-45 152.7 0.5 3.3 3 1 0 3 3 3 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 OAJ11999.1 - 4.9e-31 107.2 0.0 9.4e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 OAJ11999.1 - 1e-13 51.3 1.0 1e-13 51.3 0.7 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 OAJ11999.1 - 3.9e-11 42.5 0.1 7.8e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 OAJ11999.1 - 1.3e-09 37.9 0.3 1.3e-09 37.9 0.2 2.2 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 OAJ11999.1 - 2.3e-06 27.4 0.1 1.1e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain cNMP_binding PF00027.24 OAJ12000.1 - 6.7e-37 125.1 0.0 5.2e-17 61.4 0.0 5.5 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.17 OAJ12000.1 - 1.4e-17 64.3 7.9 3.8e-16 59.6 4.0 3.3 2 1 0 2 2 2 1 Patatin-like phospholipase Exo_endo_phos_2 PF14529.1 OAJ12010.1 - 0.00032 20.3 0.1 0.00068 19.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 OAJ12010.1 - 0.052 12.9 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 OAJ12011.1 - 1.6e-24 86.4 0.0 3.2e-24 85.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ12011.1 - 3.4e-11 42.7 0.0 6.8e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Nipped-B_C PF12830.2 OAJ12023.1 - 4.5e-40 137.2 0.2 7.1e-40 136.6 0.1 1.2 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus MFS_1 PF07690.11 OAJ12023.1 - 3.9e-26 91.6 17.1 6e-26 90.9 11.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MCM PF00493.18 OAJ12025.1 - 2.2e-129 431.0 0.0 3.2e-129 430.5 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 OAJ12025.1 - 5.6e-24 84.9 0.0 1.4e-23 83.7 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 OAJ12025.1 - 9.3e-08 31.4 0.0 1.1e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 OAJ12025.1 - 0.0036 16.8 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAJ12025.1 - 0.0056 16.1 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ12025.1 - 0.055 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) EVE PF01878.13 OAJ12026.1 - 5.5e-39 133.4 0.0 9.1e-39 132.7 0.0 1.4 1 0 0 1 1 1 1 EVE domain Asp PF00026.18 OAJ12027.1 - 2.3e-114 381.9 0.2 2.8e-114 381.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ12027.1 - 5.1e-11 42.7 0.0 1.1e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 OAJ12027.1 - 1.1e-06 28.3 0.0 3.1e-05 23.5 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 OAJ12027.1 - 4e-06 27.2 0.0 0.017 15.5 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease DUF3564 PF12087.3 OAJ12027.1 - 0.047 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) COX17 PF05051.8 OAJ12040.1 - 7.1e-18 64.3 5.7 1.2e-17 63.6 4.0 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Abhydrolase_6 PF12697.2 OAJ12042.1 - 0.0091 15.8 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family zf-DHHC PF01529.15 OAJ12043.1 - 3.1e-42 143.9 2.0 5.4e-42 143.1 0.0 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase RVT_1 PF00078.22 OAJ12057.1 - 0.0085 15.4 0.0 0.025 13.9 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 OAJ12057.1 - 0.04 13.6 0.2 0.27 11.0 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase-like Acyl-CoA_dh_1 PF00441.19 OAJ12058.1 - 4.6e-49 166.3 5.8 4.6e-49 166.3 4.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ12058.1 - 6.4e-25 86.4 0.4 2e-24 84.8 0.3 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 OAJ12058.1 - 1.3e-24 86.9 0.2 1.3e-24 86.9 0.2 2.6 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAJ12058.1 - 1.3e-18 67.5 5.8 1.3e-18 67.5 4.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 OAJ12058.1 - 1.3e-05 24.7 0.2 5.4e-05 22.7 0.1 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal TPR_1 PF00515.23 OAJ12070.1 - 1.2e-57 189.2 13.9 3.2e-07 29.6 0.0 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ12070.1 - 4.9e-51 166.5 13.9 5.8e-06 25.8 0.0 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ12070.1 - 9.3e-51 169.3 17.4 2.1e-11 43.2 0.0 6.6 4 2 2 6 6 6 6 TPR repeat TPR_8 PF13181.1 OAJ12070.1 - 1.9e-34 114.8 11.6 0.00022 20.7 0.0 10.3 7 1 3 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ12070.1 - 1.3e-33 114.8 15.6 4.1e-08 33.6 0.1 7.5 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ12070.1 - 1.9e-31 105.6 13.4 0.00014 21.7 0.2 10.3 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ12070.1 - 6.2e-31 104.0 11.0 0.00092 19.6 0.0 10.1 3 3 6 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ12070.1 - 1.4e-29 99.4 4.4 0.011 15.4 0.0 9.7 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ12070.1 - 3.5e-28 97.3 15.8 1.4e-06 28.1 0.2 6.6 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ12070.1 - 6e-27 93.7 8.2 2.1e-07 31.1 0.3 7.1 3 3 2 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ12070.1 - 4.8e-23 79.9 10.1 0.0013 19.0 0.0 10.7 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ12070.1 - 4.3e-15 55.3 10.0 0.0043 16.8 0.1 6.7 1 1 8 9 9 9 7 Tetratricopeptide repeat Apc3 PF12895.2 OAJ12070.1 - 1.1e-13 51.0 6.0 1.6e-05 24.9 0.4 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 OAJ12070.1 - 7.7e-08 31.7 9.5 0.0025 16.9 0.9 4.5 1 1 2 4 4 4 3 Tetratricopeptide repeat TOM20_plant PF06552.7 OAJ12070.1 - 0.003 17.1 0.1 3.1 7.3 0.0 3.2 2 1 1 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_20 PF14561.1 OAJ12070.1 - 0.018 15.1 0.0 0.018 15.1 0.0 4.5 6 1 0 6 6 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ12070.1 - 0.036 14.0 12.3 0.76 9.8 0.1 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.5 OAJ12070.1 - 0.041 12.6 1.0 5.3 5.6 0.1 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_WDAD PF04053.9 OAJ12070.1 - 0.32 9.7 1.1 7.9 5.1 0.1 2.2 2 0 0 2 2 2 0 Coatomer WD associated region RAB3GAP2_N PF14655.1 OAJ12070.1 - 3.4 6.5 3.8 5.6 5.8 2.6 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DSPc PF00782.15 OAJ12086.1 - 6.5e-28 96.9 0.0 7.4e-22 77.3 0.0 2.7 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAJ12086.1 - 0.00026 20.4 0.0 0.00082 18.7 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 OAJ12086.1 - 0.15 12.1 0.1 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate Abhydrolase_6 PF12697.2 OAJ12099.1 - 4.3e-06 26.7 2.6 7.4e-06 26.0 1.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ12099.1 - 0.00046 19.9 0.0 0.0008 19.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAJ12099.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Ceramidase_alk PF04734.8 OAJ12103.1 - 0.0007 17.6 0.1 0.00092 17.2 0.1 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase PHY PF00360.15 OAJ12112.1 - 0.055 12.6 0.0 0.46 9.5 0.0 2.0 2 0 0 2 2 2 0 Phytochrome region Uds1 PF15456.1 OAJ12124.1 - 0.0098 15.8 1.4 0.022 14.7 0.6 1.8 2 0 0 2 2 2 1 Up-regulated During Septation Seryl_tRNA_N PF02403.17 OAJ12124.1 - 0.048 13.6 3.4 0.26 11.3 0.5 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain eIF-3c_N PF05470.7 OAJ12124.1 - 0.058 11.4 0.3 0.081 10.9 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCRF PF03462.13 OAJ12124.1 - 0.21 11.2 1.1 0.37 10.5 0.1 1.8 2 0 0 2 2 2 0 PCRF domain GAS PF13851.1 OAJ12124.1 - 0.47 9.6 8.5 4 6.5 0.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3292 PF11696.3 OAJ12125.1 - 9.1e-07 27.1 0.2 9.1e-07 27.1 0.1 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3292) PRT_C PF08372.5 OAJ12125.1 - 0.00039 19.9 3.3 0.0031 17.0 0.6 2.3 1 1 1 2 2 2 2 Plant phosphoribosyltransferase C-terminal PH_BEACH PF14844.1 OAJ12125.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH Reticulon PF02453.12 OAJ12125.1 - 0.35 10.4 6.1 8.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Reticulon ThiF PF00899.16 OAJ12126.1 - 1e-39 135.4 0.0 5.6e-39 133.0 0.0 1.9 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 OAJ12126.1 - 3.4e-24 84.1 0.6 6.5e-24 83.2 0.4 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 OAJ12126.1 - 7.6e-23 80.0 0.0 1.3e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 OAJ12126.1 - 1.5e-18 65.9 1.6 3.1e-18 64.8 1.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 OAJ12126.1 - 0.001 19.1 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 OAJ12126.1 - 0.0074 15.8 0.4 0.023 14.2 0.0 1.9 2 0 0 2 2 2 1 MoeZ/MoeB domain DAO PF01266.19 OAJ12126.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 OAJ12126.1 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Ecm33 PF12454.3 OAJ12126.1 - 0.27 11.1 2.3 0.51 10.2 1.6 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein NAD_binding_8 PF13450.1 OAJ12128.1 - 7e-10 38.7 0.1 1.5e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 OAJ12128.1 - 2e-07 30.4 0.0 9.3e-05 21.6 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 OAJ12128.1 - 0.00011 22.3 0.0 0.00024 21.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ12128.1 - 0.01 15.7 0.1 0.022 14.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAJ12128.1 - 0.021 13.9 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAJ12128.1 - 0.034 13.1 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 OAJ12128.1 - 0.041 12.3 0.1 0.059 11.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 OAJ12128.1 - 0.068 12.0 0.2 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 OAJ12128.1 - 0.082 11.9 0.1 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 OAJ12128.1 - 0.089 11.6 0.3 0.14 10.9 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 OAJ12128.1 - 0.32 10.7 0.0 0.32 10.7 0.0 2.5 3 0 0 3 3 2 0 FAD-NAD(P)-binding Fungal_trans PF04082.13 OAJ12137.1 - 6.3e-06 25.2 0.1 1.1e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ12137.1 - 0.0047 16.8 14.8 0.0076 16.1 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clat_adaptor_s PF01217.15 OAJ12138.1 - 1.2e-43 148.2 0.3 4.2e-34 117.3 0.2 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain MAGE_N PF12440.3 OAJ12138.1 - 0.13 12.5 2.8 1.6 9.0 0.3 2.2 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Herpes_capsid PF06112.6 OAJ12138.1 - 3 7.8 11.3 1.3 9.0 1.1 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Thr_synth_N PF14821.1 OAJ12139.1 - 6.8e-27 93.3 0.0 2.3e-26 91.5 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 OAJ12139.1 - 1.4e-21 77.0 0.0 3.1e-20 72.6 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme WD40 PF00400.27 OAJ12140.1 - 2.9e-38 128.3 10.4 1.5e-08 34.2 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 OAJ12140.1 - 3.7e-30 103.6 0.1 7.8e-30 102.6 0.1 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Apc4_WD40 PF12894.2 OAJ12140.1 - 0.0015 17.9 0.1 1.1 8.7 0.0 3.8 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S7e PF01251.13 OAJ12141.1 - 1.5e-79 265.8 0.1 1.9e-79 265.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e Rad51 PF08423.6 OAJ12142.1 - 3.6e-138 458.6 0.1 4.4e-138 458.3 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 OAJ12142.1 - 1.7e-15 56.9 0.0 2.5e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 OAJ12142.1 - 7.4e-09 35.0 0.1 1e-08 34.6 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 OAJ12142.1 - 2.5e-08 33.9 0.0 5.3e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 OAJ12142.1 - 5.5e-08 32.1 0.0 8.8e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 KaiC PAXNEB PF05625.6 OAJ12142.1 - 0.01 14.7 0.7 0.026 13.3 0.3 1.7 1 1 1 2 2 2 0 PAXNEB protein HHH PF00633.18 OAJ12142.1 - 0.012 15.2 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif AAA_22 PF13401.1 OAJ12142.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.10 OAJ12142.1 - 0.15 10.9 0.1 0.32 9.8 0.0 1.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAT1 PF09770.4 OAJ12150.1 - 0.027 12.7 71.0 0.038 12.2 49.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 OAJ12150.1 - 0.57 9.5 24.2 0.94 8.8 16.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MARVEL PF01284.18 OAJ12151.1 - 0.1 12.4 16.5 0.42 10.4 11.1 2.2 1 1 0 1 1 1 0 Membrane-associating domain HSF_DNA-bind PF00447.12 OAJ12152.1 - 4.8e-31 107.0 0.2 7.1e-31 106.4 0.2 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Nucleoplasmin PF03066.10 OAJ12152.1 - 0.039 13.4 2.8 0.067 12.7 1.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 OAJ12152.1 - 0.95 7.8 9.9 3.9 5.8 0.1 2.2 2 0 0 2 2 2 0 Daxx Family PBP1_TM PF14812.1 OAJ12152.1 - 4.2 7.7 7.2 13 6.2 5.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 OAJ12152.1 - 4.6 7.5 10.1 10 6.4 7.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 OAJ12152.1 - 8.5 5.9 7.6 11 5.5 4.1 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Alpha-amylase_C PF02806.13 OAJ12153.1 - 1.2e-26 92.6 0.2 3.5e-26 91.1 0.1 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 OAJ12153.1 - 2.3e-19 69.9 0.0 4.2e-15 55.9 0.0 2.6 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 OAJ12153.1 - 4.2e-14 52.3 0.4 1.2e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) AP_endonuc_2 PF01261.19 OAJ12153.1 - 0.0075 15.5 0.0 0.021 14.0 0.0 1.8 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_hydro_66 PF13199.1 OAJ12153.1 - 0.023 13.1 0.1 0.042 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 hDGE_amylase PF14701.1 OAJ12153.1 - 0.034 13.0 0.0 0.9 8.3 0.0 2.1 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme Aminotran_1_2 PF00155.16 OAJ12153.1 - 0.12 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II AA_kinase PF00696.23 OAJ12167.1 - 1.3e-36 126.3 0.0 3.3e-31 108.6 0.0 2.2 2 0 0 2 2 2 2 Amino acid kinase family ACT PF01842.20 OAJ12167.1 - 1.1e-08 34.3 0.1 0.00015 21.1 0.0 3.0 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 OAJ12167.1 - 3e-06 26.6 0.2 3e-06 26.6 0.1 2.1 2 0 0 2 2 2 1 ACT domain PPR_2 PF13041.1 OAJ12168.1 - 5.7e-32 109.4 7.0 4.4e-11 42.5 0.1 9.4 7 2 4 11 11 11 7 PPR repeat family PPR_3 PF13812.1 OAJ12168.1 - 2.1e-30 102.3 8.4 0.00031 20.7 0.1 11.6 9 2 2 11 11 11 5 Pentatricopeptide repeat domain PPR PF01535.15 OAJ12168.1 - 4.5e-26 88.9 9.4 1.9e-06 27.4 0.1 11.2 12 0 0 12 12 12 5 PPR repeat PPR_1 PF12854.2 OAJ12168.1 - 1e-11 44.0 6.8 0.00015 21.1 0.0 7.0 7 1 0 7 7 7 2 PPR repeat TPR_7 PF13176.1 OAJ12168.1 - 0.00035 20.1 0.2 3.6 7.6 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ12168.1 - 0.39 11.0 11.8 40 4.6 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat Hist_deacetyl PF00850.14 OAJ12169.1 - 6.4e-79 265.4 0.0 9.2e-79 264.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ArgJ PF01960.13 OAJ12170.1 - 6.4e-126 419.8 0.0 1.1e-125 419.1 0.0 1.3 1 1 0 1 1 1 1 ArgJ family Amidase_2 PF01510.20 OAJ12171.1 - 0.028 14.4 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase Exo_endo_phos_2 PF14529.1 OAJ12182.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.5 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase DEAD PF00270.24 OAJ12192.1 - 0.00013 21.5 0.0 0.00015 21.2 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 OAJ12192.1 - 0.13 12.0 0.1 0.19 11.5 0.0 1.4 1 1 0 1 1 1 0 Part of AAA domain Myb_DNA-bind_4 PF13837.1 OAJ12193.1 - 6.9e-05 22.8 0.2 0.00022 21.2 0.1 2.0 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF362 PF04015.7 OAJ12193.1 - 0.14 11.5 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF362) Cytochrom_NNT PF03264.9 OAJ12193.1 - 2.1 7.7 6.9 6.6 6.1 1.0 2.2 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region DEAD PF00270.24 OAJ12205.1 - 3.7e-30 104.6 0.0 8.2e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ12205.1 - 1.3e-20 72.9 0.0 9.8e-12 44.5 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ12205.1 - 9.9e-05 22.2 0.0 9.9e-05 22.2 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 OAJ12205.1 - 0.0077 14.6 0.1 0.49 8.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) LIM PF00412.17 OAJ12206.1 - 1.4e-14 53.8 14.7 0.00021 21.2 0.0 5.5 6 0 0 6 6 6 4 LIM domain RhoGAP PF00620.22 OAJ12207.1 - 2.1e-45 154.0 0.0 3.7e-45 153.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 OAJ12207.1 - 5.5e-17 61.7 0.8 1.9e-16 60.0 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PDEase_II PF02112.10 OAJ12208.1 - 2e-40 138.7 0.0 2.3e-20 72.8 0.0 3.6 4 0 0 4 4 4 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 OAJ12208.1 - 0.00091 18.8 0.0 0.029 13.9 0.0 2.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain SR-25 PF10500.4 OAJ12208.1 - 0.0072 15.8 4.0 0.0072 15.8 2.7 4.6 5 0 0 5 5 5 1 Nuclear RNA-splicing-associated protein GARS_A PF01071.14 OAJ12218.1 - 2.8e-67 226.0 0.0 4.1e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 OAJ12218.1 - 1.7e-31 108.6 0.0 5.3e-31 107.0 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 OAJ12218.1 - 1.2e-26 92.7 0.1 2.8e-26 91.5 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS_C PF02769.17 OAJ12218.1 - 2.4e-25 89.3 0.0 5e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 OAJ12218.1 - 7.7e-17 61.3 2.1 1.7e-16 60.1 0.7 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Shikimate_DH PF01488.15 OAJ12218.1 - 0.039 14.0 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase LtrA PF06772.6 OAJ12219.1 - 1.8e-17 63.3 12.2 2.5e-17 62.8 8.5 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) WD40 PF00400.27 OAJ12220.1 - 2.5e-51 169.8 23.4 1.1e-08 34.5 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Sfi1 PF08457.5 OAJ12220.1 - 0.17 10.2 0.3 0.21 9.9 0.2 1.1 1 0 0 1 1 1 0 Sfi1 spindle body protein 4HBT_2 PF13279.1 OAJ12221.1 - 9.3e-17 61.5 0.0 1.6e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 OAJ12221.1 - 0.00041 19.3 0.1 0.001 18.0 0.1 1.6 2 0 0 2 2 2 1 Acyl-ACP thioesterase 4HBT PF03061.17 OAJ12221.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.6 1 1 0 1 1 1 0 Thioesterase superfamily adh_short PF00106.20 OAJ12222.1 - 3.5e-20 72.5 0.0 5.3e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ12222.1 - 3e-06 27.1 0.0 4.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ12222.1 - 6.5e-06 25.9 0.1 1.9e-05 24.3 0.1 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAJ12222.1 - 0.00049 19.5 0.0 0.00074 19.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family WD40 PF00400.27 OAJ12223.1 - 2.6e-24 84.1 7.6 2e-10 40.1 0.5 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 OAJ12223.1 - 1.1e-17 63.6 0.0 2.8e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Med21 PF11221.3 OAJ12234.1 - 7.2e-17 61.6 1.6 1e-16 61.2 1.1 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex IncA PF04156.9 OAJ12234.1 - 0.18 11.3 3.7 0.24 10.9 2.6 1.1 1 0 0 1 1 1 0 IncA protein Sugar_tr PF00083.19 OAJ12237.1 - 5.3e-86 288.9 25.3 6.5e-86 288.6 17.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ12237.1 - 5.9e-14 51.5 41.2 3.1e-12 45.8 9.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DHH PF01368.15 OAJ12238.1 - 4.4e-08 32.8 0.3 2.8e-07 30.2 0.0 2.4 2 2 0 2 2 2 1 DHH family DHHA2 PF02833.9 OAJ12238.1 - 9.1e-05 22.6 0.0 0.0002 21.5 0.0 1.5 1 0 0 1 1 1 1 DHHA2 domain RRS1 PF04939.7 OAJ12247.1 - 6.1e-53 178.6 0.6 7.3e-53 178.4 0.4 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Complex1_51K PF01512.12 OAJ12248.1 - 2.6e-48 163.5 0.0 4.5e-48 162.8 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 OAJ12248.1 - 1e-20 72.6 0.4 2.2e-20 71.5 0.3 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 OAJ12248.1 - 1.6e-07 31.0 0.0 3.6e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 SLBB domain Abhydrolase_5 PF12695.2 OAJ12249.1 - 9.2e-05 22.2 0.0 0.00016 21.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAJ12249.1 - 0.00012 21.7 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 OAJ12249.1 - 0.00048 19.4 0.0 0.00074 18.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 OAJ12249.1 - 0.0005 19.1 0.0 0.00065 18.7 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 OAJ12249.1 - 0.0011 18.9 0.1 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ12249.1 - 0.0082 15.7 0.0 0.048 13.2 0.0 1.7 1 1 0 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.6 OAJ12249.1 - 0.078 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) UPF0227 PF05728.7 OAJ12249.1 - 0.093 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Aminotran_1_2 PF00155.16 OAJ12250.1 - 3e-89 299.5 0.0 3.4e-89 299.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.16 OAJ12251.1 - 2.2e-69 234.1 0.0 2.9e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 OAJ12251.1 - 6.4e-05 21.8 0.0 0.0001 21.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 OAJ12251.1 - 0.002 16.4 0.0 0.0048 15.2 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Peptidase_S24 PF00717.18 OAJ12252.1 - 5.4e-09 35.5 0.0 1.1e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_C14 PF00656.17 OAJ12253.1 - 1.8e-64 217.8 0.0 2.2e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DXP_synthase_N PF13292.1 OAJ12253.1 - 0.12 11.2 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Pkinase PF00069.20 OAJ12267.1 - 3.4e-40 137.8 0.0 5.3e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ12267.1 - 3.9e-25 88.4 0.0 5.9e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ12267.1 - 0.0023 16.9 0.0 0.0037 16.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ12267.1 - 0.004 16.9 0.0 0.008 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ12267.1 - 0.59 9.1 0.0 1 8.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 OAJ12267.1 - 1.2 7.8 0.0 1.9 7.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 PS_Dcarbxylase PF02666.10 OAJ12268.1 - 4e-41 140.5 0.0 5.3e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Cutinase PF01083.17 OAJ12269.1 - 4.7e-30 104.6 0.0 5.6e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ12269.1 - 0.00017 21.2 0.0 0.00017 21.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ12269.1 - 0.0044 16.7 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ12269.1 - 0.013 15.4 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIP PF03583.9 OAJ12269.1 - 0.15 11.2 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Secretory lipase adh_short PF00106.20 OAJ12270.1 - 1.1e-26 93.6 0.9 1.9e-26 92.9 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ12270.1 - 9.3e-24 84.5 0.3 7.3e-11 42.2 0.1 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ12270.1 - 2.3e-17 63.2 0.5 6.1e-17 61.8 0.1 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 OAJ12270.1 - 0.00071 19.0 0.0 0.00084 18.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 OAJ12270.1 - 0.0067 16.0 2.0 0.04 13.5 0.6 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 OAJ12270.1 - 0.026 14.5 1.3 0.045 13.7 0.3 1.8 2 1 0 2 2 2 0 NADH(P)-binding Glyco_trans_4_4 PF13579.1 OAJ12270.1 - 0.042 13.9 0.1 2 8.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain F420_oxidored PF03807.12 OAJ12270.1 - 0.097 13.1 2.9 25 5.4 0.3 3.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent FBP PF07299.6 OAJ12271.1 - 0.054 12.8 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) Glyco_hydro_8 PF01270.12 OAJ12283.1 - 1.7e-37 128.9 0.0 2e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 Peptidase_S29 PF02907.10 OAJ12283.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Nop14 PF04147.7 OAJ12285.1 - 0.046 11.6 7.1 0.055 11.3 5.0 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 OAJ12285.1 - 3.6 7.0 10.3 6.2 6.3 1.9 2.2 2 0 0 2 2 2 0 Nucleoplasmin Cut8_N PF14482.1 OAJ12285.1 - 3.7 7.6 12.3 0.27 11.2 1.6 3.4 2 1 1 3 3 3 0 Cut8 proteasome-binding domain Spo7 PF03907.8 OAJ12286.1 - 8.7e-10 38.5 0.2 0.00057 19.5 0.0 2.1 2 0 0 2 2 2 2 Spo7-like protein MARVEL PF01284.18 OAJ12286.1 - 0.6 9.9 8.1 0.15 11.8 0.5 2.6 3 0 0 3 3 3 0 Membrane-associating domain DUF3989 PF13150.1 OAJ12286.1 - 0.7 9.3 5.9 5 6.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) GTP_EFTU PF00009.22 OAJ12287.1 - 6.3e-39 133.3 0.0 9.9e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 OAJ12287.1 - 2.8e-27 94.6 0.0 6.2e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 OAJ12287.1 - 2.2e-19 69.1 0.0 6.2e-19 67.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus Miro PF08477.8 OAJ12287.1 - 8.5e-08 32.7 0.0 1.9e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 OAJ12287.1 - 2.8e-07 30.5 1.5 4e-07 30.0 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAJ12287.1 - 1.2e-06 28.5 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 OAJ12287.1 - 7.1e-05 22.5 0.1 0.00015 21.5 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.17 OAJ12287.1 - 0.00063 19.1 0.0 0.0018 17.6 0.0 1.8 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.18 OAJ12287.1 - 0.048 13.4 0.2 6.7 6.4 0.0 2.3 1 1 1 2 2 2 0 Dynamin family SRPRB PF09439.5 OAJ12287.1 - 0.089 12.0 0.2 0.29 10.3 0.0 1.9 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Serglycin PF04360.7 OAJ12288.1 - 0.083 12.6 1.7 0.095 12.4 0.2 1.9 2 0 0 2 2 2 0 Serglycin PSK_trans_fac PF07704.6 OAJ12288.1 - 4.7 7.9 6.4 3.7 8.3 0.1 2.8 3 0 0 3 3 3 0 Rv0623-like transcription factor Nucleoplasmin PF03066.10 OAJ12305.1 - 0.021 14.3 2.0 0.019 14.4 1.4 1.1 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 OAJ12305.1 - 0.45 9.6 3.7 0.46 9.5 2.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.7 OAJ12305.1 - 1.5 8.0 4.7 1.6 7.9 3.3 1.1 1 0 0 1 1 1 0 NOA36 protein hDGE_amylase PF14701.1 OAJ12306.1 - 5.2e-158 526.3 0.0 7.4e-158 525.8 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 OAJ12306.1 - 1.7e-106 356.0 0.0 2.4e-106 355.5 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 OAJ12306.1 - 7.8e-81 271.0 0.0 1.2e-80 270.4 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 OAJ12306.1 - 1.3e-18 66.5 0.0 2.6e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 OAJ12306.1 - 0.0043 16.4 0.0 0.28 10.5 0.0 2.3 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Mucin PF01456.12 OAJ12306.1 - 7.2 6.3 16.6 15 5.3 11.5 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF92 PF01940.11 OAJ12308.1 - 3.7e-51 173.4 3.8 1.6e-49 168.0 2.7 2.1 1 1 0 1 1 1 1 Integral membrane protein DUF92 Sulfate_transp PF00916.15 OAJ12309.1 - 2.9e-78 262.7 8.1 5e-78 261.9 5.6 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 OAJ12309.1 - 1.6e-30 104.6 4.0 1.6e-30 104.6 2.8 3.7 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 OAJ12309.1 - 3.8e-10 39.1 0.0 7.3e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain F-box-like PF12937.2 OAJ12323.1 - 0.0059 16.2 1.7 0.0074 15.9 0.0 2.0 3 0 0 3 3 3 1 F-box-like U79_P34 PF03064.11 OAJ12324.1 - 0.34 10.3 2.9 0.61 9.5 2.0 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Claudin_2 PF13903.1 OAJ12325.1 - 0.026 14.2 0.8 0.053 13.2 0.3 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF3648 PF12364.3 OAJ12325.1 - 0.078 12.9 0.1 0.5 10.3 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3648) MARVEL PF01284.18 OAJ12325.1 - 0.5 10.1 7.3 3.3 7.5 5.0 2.2 1 1 0 1 1 1 0 Membrane-associating domain CRPA PF05745.6 OAJ12326.1 - 0.25 11.1 1.5 0.44 10.3 1.0 1.4 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Claudin_2 PF13903.1 OAJ12326.1 - 0.76 9.4 5.6 2.4 7.7 0.0 2.6 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Thiolase_N PF00108.18 OAJ12337.1 - 6.1e-83 277.8 4.9 6.1e-83 277.8 3.4 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAJ12337.1 - 7e-44 148.1 0.6 1.6e-43 147.0 0.4 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 OAJ12337.1 - 0.24 10.8 5.0 0.17 11.3 0.3 2.9 3 1 1 4 4 4 0 Beta-ketoacyl synthase, N-terminal domain Reprolysin_5 PF13688.1 OAJ12338.1 - 3e-45 154.5 5.2 3e-45 154.5 3.6 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 OAJ12338.1 - 1.1e-43 149.1 0.2 2.5e-43 148.0 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 OAJ12338.1 - 1.7e-39 135.6 3.8 1.8e-39 135.5 1.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 OAJ12338.1 - 4.5e-18 65.9 0.0 1.2e-17 64.6 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 OAJ12338.1 - 1.3e-13 50.9 22.4 1.3e-13 50.9 15.5 4.1 3 1 1 4 4 4 1 Disintegrin Reprolysin PF01421.14 OAJ12338.1 - 5.6e-09 35.8 2.8 2.5e-07 30.4 0.0 3.3 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 OAJ12338.1 - 3.4e-08 33.3 0.1 8e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M66 PF10462.4 OAJ12338.1 - 0.19 10.5 0.1 0.34 9.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Histone PF00125.19 OAJ12339.1 - 5.5e-29 100.1 1.1 8.4e-29 99.5 0.7 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ12339.1 - 4.7e-05 23.4 0.1 7.2e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAJ12339.1 - 0.0019 18.2 0.2 0.0037 17.2 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 OAJ12339.1 - 0.028 14.1 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Ran_BP1 PF00638.13 OAJ12340.1 - 6.3e-15 55.3 0.0 2e-07 31.0 0.0 2.3 2 0 0 2 2 2 2 RanBP1 domain Syntaxin PF00804.20 OAJ12341.1 - 5.4e-12 45.7 1.4 5.4e-12 45.7 1.0 2.6 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.14 OAJ12341.1 - 2.2e-08 33.6 12.6 3.1e-07 29.9 4.2 3.6 3 0 0 3 3 3 1 SNARE domain TPR_10 PF13374.1 OAJ12341.1 - 0.058 13.3 0.3 0.7 9.9 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec8_exocyst PF04048.9 OAJ12341.1 - 0.13 11.8 5.6 0.096 12.3 1.6 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain GRP PF07172.6 OAJ12341.1 - 0.16 12.4 10.6 1.2 9.6 6.4 2.7 2 0 0 2 2 2 0 Glycine rich protein family DUF2721 PF11026.3 OAJ12341.1 - 0.26 10.9 3.8 12 5.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) TPR_16 PF13432.1 OAJ12341.1 - 0.46 11.2 3.5 1.2 9.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Herpes_US9 PF06072.6 OAJ12341.1 - 1.1 9.1 3.3 2.3 8.1 2.3 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Muted PF14942.1 OAJ12341.1 - 1.5 8.7 13.3 0.07 13.0 2.0 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Syntaxin_2 PF14523.1 OAJ12341.1 - 3.3 7.8 11.5 0.32 11.0 2.5 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Histone PF00125.19 OAJ12342.1 - 8.6e-14 51.4 0.1 1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ12342.1 - 0.00012 22.2 0.0 0.00016 21.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 OAJ12342.1 - 0.00024 20.9 0.1 0.00034 20.4 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 OAJ12342.1 - 0.00077 19.4 0.1 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 OAJ12342.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Endonuclease_5 PF04493.9 OAJ12350.1 - 2.3e-37 128.3 0.0 3.9e-37 127.6 0.0 1.5 1 1 0 1 1 1 1 Endonuclease V E1-E2_ATPase PF00122.15 OAJ12351.1 - 5.6e-54 182.6 0.0 1.3e-48 165.0 0.0 2.5 1 1 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAJ12351.1 - 9.7e-35 119.7 1.5 9.7e-35 119.7 1.1 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ12351.1 - 2.6e-26 93.3 3.4 2.8e-21 76.9 0.1 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAJ12351.1 - 1.8e-16 59.3 2.3 2.1e-16 59.1 0.0 2.3 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 OAJ12351.1 - 7.3e-12 45.0 0.0 1.6e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 OAJ12351.1 - 3.3e-11 43.7 0.0 1.2e-10 41.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ12351.1 - 0.061 12.8 0.1 1.9 7.9 0.1 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ACOX PF01756.14 OAJ12352.1 - 4.4e-45 153.3 0.0 7.3e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 OAJ12352.1 - 5.4e-15 54.6 0.7 1.4e-14 53.2 0.2 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 OAJ12352.1 - 3.7e-11 43.4 0.0 1.1e-10 41.9 0.0 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 OAJ12352.1 - 8.5e-10 38.9 0.9 3.5e-09 36.9 0.6 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AhpC-TSA PF00578.16 OAJ12353.1 - 3.1e-34 117.3 0.0 4.4e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 OAJ12353.1 - 1.3e-13 50.7 0.0 1.6e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 OAJ12353.1 - 7.7e-11 41.4 0.1 1.5e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin GATase_2 PF00310.16 OAJ12353.1 - 0.11 11.2 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferases class-II XPA_C PF05181.7 OAJ12354.1 - 2.7e-27 94.0 1.2 6.2e-27 92.9 0.8 1.7 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 OAJ12354.1 - 0.86 9.3 6.8 0.39 10.4 0.8 2.3 2 0 0 2 2 2 0 XPA protein N-terminal Stc1 PF12898.2 OAJ12354.1 - 4.5 7.3 7.9 8.4 6.5 0.4 2.8 2 1 0 2 2 2 0 Stc1 domain SPT6_acidic PF14632.1 OAJ12354.1 - 9.6 6.4 8.9 0.34 11.0 0.5 2.4 2 0 0 2 2 2 0 Acidic N-terminal SPT6 DWNN PF08783.6 OAJ12365.1 - 5.4e-31 106.3 0.0 9.7e-31 105.5 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 OAJ12365.1 - 4.5e-06 26.0 3.5 1e-05 24.8 2.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 OAJ12365.1 - 1.7e-05 24.5 2.0 3.3e-05 23.5 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 OAJ12365.1 - 0.00055 19.9 12.0 0.00055 19.9 8.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.1 OAJ12365.1 - 0.002 17.7 0.1 0.0067 16.1 0.1 1.9 1 0 0 1 1 1 1 Zinc knuckle Suf PF05843.9 OAJ12365.1 - 0.44 10.2 3.2 0.82 9.3 2.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-C3HC4_3 PF13920.1 OAJ12365.1 - 5 6.8 13.2 0.75 9.5 6.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TFIIF_alpha PF05793.7 OAJ12366.1 - 0.76 8.0 11.2 1.8 6.8 7.8 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.5 OAJ12366.1 - 0.96 8.4 10.8 1.6 7.6 7.5 1.3 1 0 0 1 1 1 0 BUD22 CN_hydrolase PF00795.17 OAJ12367.1 - 3.7e-10 39.4 0.0 6.6e-09 35.3 0.0 2.2 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_S8 PF00082.17 OAJ12368.1 - 1.2e-45 155.9 0.0 2.5e-45 154.8 0.0 1.6 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 OAJ12368.1 - 5.8e-11 42.7 0.1 1.2e-10 41.7 0.1 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 OAJ12368.1 - 8.4e-09 35.0 0.6 2e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 PA domain IBR PF01485.16 OAJ12382.1 - 7.2e-07 28.9 27.4 0.00048 19.9 2.7 3.6 3 0 0 3 3 3 3 IBR domain COX5A PF02284.11 OAJ12383.1 - 2.7e-41 139.9 0.4 3.6e-41 139.4 0.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Mt_ATP-synt_B PF05405.9 OAJ12384.1 - 3.7e-46 156.5 7.1 4.6e-46 156.2 4.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2730 PF10805.3 OAJ12384.1 - 0.00013 21.6 0.5 0.00024 20.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) DUF445 PF04286.7 OAJ12384.1 - 0.032 13.7 4.6 0.043 13.3 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF1539 PF07560.6 OAJ12384.1 - 0.069 13.0 0.2 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Cauli_DNA-bind PF03310.8 OAJ12384.1 - 0.077 12.8 3.0 0.07 12.9 0.7 1.8 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein RICTOR_M PF14666.1 OAJ12385.1 - 4.9e-69 231.8 0.0 6.9e-68 228.0 0.0 2.8 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.1 OAJ12385.1 - 1.9e-49 168.2 0.0 7.7e-40 136.6 0.0 3.5 4 1 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.1 OAJ12385.1 - 1e-25 89.9 0.0 4.4e-25 87.8 0.0 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 OAJ12385.1 - 2.2e-25 88.3 0.2 5.5e-24 83.8 0.0 3.1 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 OAJ12385.1 - 0.00036 20.2 0.0 0.0008 19.1 0.0 1.6 1 0 0 1 1 1 1 Hr1 repeat HEAT PF02985.17 OAJ12385.1 - 0.18 11.9 0.5 2.8 8.2 0.2 3.0 2 0 0 2 2 2 0 HEAT repeat Coa1 PF08695.5 OAJ12386.1 - 1.3e-30 105.3 0.0 1.8e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF4633 PF15464.1 OAJ12387.1 - 0.16 11.7 1.5 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) TPR_12 PF13424.1 OAJ12404.1 - 3.8e-11 42.7 16.8 0.0016 18.2 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ12404.1 - 3.5e-08 32.7 1.6 0.21 11.2 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ12404.1 - 4.4e-07 29.3 10.4 0.035 14.0 0.1 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ12404.1 - 5.4e-06 25.9 11.4 0.00092 18.8 0.0 4.7 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.1 OAJ12404.1 - 0.0052 17.3 15.0 2.9 8.7 0.2 8.2 8 1 1 9 9 8 1 Tetratricopeptide repeat Apc3 PF12895.2 OAJ12404.1 - 0.0059 16.7 5.3 0.77 9.9 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 OAJ12404.1 - 0.013 15.2 3.3 21 5.1 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ12404.1 - 0.013 15.2 4.1 18 5.4 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Phage_term_smal PF05944.7 OAJ12404.1 - 0.039 13.6 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Phage small terminase subunit MIT PF04212.13 OAJ12404.1 - 0.13 12.1 2.3 0.21 11.4 0.2 2.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain SDA1 PF05285.7 OAJ12404.1 - 8.5 5.5 8.6 16 4.6 6.0 1.4 1 0 0 1 1 1 0 SDA1 MTP18 PF10558.4 OAJ12405.1 - 2.4e-51 173.5 1.3 4.7e-51 172.6 0.9 1.5 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF3464 PF11947.3 OAJ12405.1 - 0.038 13.4 0.1 0.038 13.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) AhpC-TSA PF00578.16 OAJ12406.1 - 1.7e-24 85.8 0.0 2.8e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 OAJ12406.1 - 2.1e-10 40.3 0.0 3.9e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Redoxin RVT_2 PF07727.9 OAJ12407.1 - 8.3e-81 270.5 0.0 1.1e-80 270.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phosphodiest PF01663.17 OAJ12419.1 - 0.00016 21.1 0.1 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase zf-TFIIB PF13453.1 OAJ12419.1 - 0.0089 15.2 0.1 0.024 13.8 0.0 1.7 2 0 0 2 2 2 1 Transcription factor zinc-finger DDOST_48kD PF03345.9 OAJ12420.1 - 4.7e-58 196.7 0.0 3.8e-54 183.8 0.0 2.2 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta adh_short PF00106.20 OAJ12420.1 - 0.00096 19.1 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 OAJ12420.1 - 0.026 14.3 0.5 0.068 12.9 0.2 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LSM PF01423.17 OAJ12421.1 - 5.8e-20 70.6 0.1 7.1e-20 70.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Zn_clus PF00172.13 OAJ12422.1 - 1.2e-08 34.6 10.4 1.8e-08 34.1 7.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim54 PF11711.3 OAJ12423.1 - 2.7e-49 167.7 0.0 4.4e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 GTP_EFTU PF00009.22 OAJ12424.1 - 6e-59 198.6 0.5 9.1e-59 198.0 0.4 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 OAJ12424.1 - 1.1e-28 99.2 0.0 2.5e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 OAJ12424.1 - 3.1e-16 59.2 3.1 3.1e-16 59.2 2.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAJ12424.1 - 1.3e-05 25.1 0.1 2.9e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAJ12424.1 - 0.0048 17.3 0.1 0.0085 16.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 OAJ12424.1 - 0.076 12.5 0.4 8.9 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 OAJ12424.1 - 0.077 12.4 0.9 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Myb_DNA-bind_3 PF12776.2 OAJ12439.1 - 2.1e-12 47.5 0.1 4.6e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MULE PF10551.4 OAJ12440.1 - 3.6e-05 23.8 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 OAJ12440.1 - 0.014 14.8 0.8 0.039 13.4 0.5 1.8 1 0 0 1 1 1 0 SWIM zinc finger N_NLPC_P60 PF12912.2 OAJ12453.1 - 0.083 12.9 0.2 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term Glucos_trans_II PF14264.1 OAJ12453.1 - 0.086 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII zf-RING_2 PF13639.1 OAJ12454.1 - 2.3e-08 33.7 11.2 0.00014 21.6 0.6 2.4 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ12454.1 - 2.1e-07 30.8 16.7 3.9e-05 23.5 3.4 2.9 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ12454.1 - 1.6e-05 24.5 13.5 6.3e-05 22.6 1.8 2.9 2 1 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAJ12454.1 - 2e-05 24.1 13.2 0.022 14.4 0.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 OAJ12454.1 - 4.8e-05 22.6 14.9 0.00044 19.5 0.1 3.0 2 1 2 4 4 4 2 Rtf2 RING-finger FYVE PF01363.16 OAJ12454.1 - 0.0024 17.7 8.5 0.0033 17.2 1.7 2.8 2 1 0 2 2 2 1 FYVE zinc finger zf-RING_UBOX PF13445.1 OAJ12454.1 - 0.13 12.0 7.6 1.4 8.7 0.3 2.7 2 0 0 2 2 2 0 RING-type zinc-finger Calici_PP_N PF08405.6 OAJ12454.1 - 0.14 10.9 0.1 0.29 9.9 0.1 1.4 1 0 0 1 1 1 0 Viral polyprotein N-terminal zf-C3HC4_4 PF15227.1 OAJ12454.1 - 0.15 11.9 17.0 0.093 12.6 2.7 3.3 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 OAJ12454.1 - 0.17 11.5 17.4 0.18 11.4 3.6 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TerY-C PF15616.1 OAJ12454.1 - 0.2 11.5 11.2 0.38 10.6 0.3 3.2 2 1 1 3 3 3 0 TerY-C metal binding domain Vps39_2 PF10367.4 OAJ12454.1 - 0.32 11.1 4.2 0.47 10.6 0.2 3.0 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 Atg14 PF10186.4 OAJ12454.1 - 2 7.3 12.5 2.9 6.7 8.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TBP PF00352.16 OAJ12455.1 - 9.7e-69 226.7 0.2 1.7e-34 117.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 OAJ12455.1 - 0.00012 22.1 0.0 0.47 10.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF500 PF04366.7 OAJ12457.1 - 2.6e-36 123.8 0.5 5.4e-36 122.8 0.3 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_9 PF14604.1 OAJ12457.1 - 3.1e-13 49.0 0.0 5.6e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ12457.1 - 1e-11 44.0 0.0 1.8e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ12457.1 - 6.1e-10 38.4 0.0 1.2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4448 PF14610.1 OAJ12470.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Asn_synthase PF00733.16 OAJ12471.1 - 8.9e-28 97.4 0.0 3.4e-27 95.5 0.0 1.8 2 0 0 2 2 2 1 Asparagine synthase G_glu_transpept PF01019.16 OAJ12472.1 - 0.097 11.1 0.0 0.12 10.8 0.0 1.0 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Transposase_21 PF02992.9 OAJ12486.1 - 0.0019 17.3 0.0 0.004 16.2 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 KIF1B PF12423.3 OAJ12486.1 - 0.051 13.6 0.2 0.16 12.0 0.1 1.8 1 0 0 1 1 1 0 Kinesin protein 1B BUD22 PF09073.5 OAJ12487.1 - 3.1 6.7 18.1 5.9 5.8 12.6 1.4 1 0 0 1 1 1 0 BUD22 Pheromone PF08015.6 OAJ12487.1 - 3.1 8.6 12.7 5.4 7.9 4.5 3.3 3 0 0 3 3 3 0 Fungal mating-type pheromone ELFV_dehydrog_N PF02812.13 OAJ12488.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ICE2 PF08426.5 OAJ12488.1 - 0.037 12.6 0.1 0.13 10.8 0.0 1.9 2 0 0 2 2 2 0 ICE2 CDC45 PF02724.9 OAJ12488.1 - 0.37 8.7 5.0 2 6.3 4.4 1.5 2 0 0 2 2 2 0 CDC45-like protein Peroxin-3 PF04882.7 OAJ12498.1 - 7.4e-08 31.5 0.0 1.1e-05 24.4 0.0 2.3 2 1 0 2 2 2 2 Peroxin-3 H_lectin PF09458.5 OAJ12500.1 - 1.1e-14 53.8 0.0 9.9e-07 28.3 0.0 2.6 2 0 0 2 2 2 2 H-type lectin domain 2OG-FeII_Oxy PF03171.15 OAJ12501.1 - 0.021 15.1 0.0 0.063 13.5 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Helitron_like_N PF14214.1 OAJ12513.1 - 2.7e-65 219.5 0.1 4.8e-65 218.7 0.1 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus F-box-like PF12937.2 OAJ12513.1 - 0.00041 20.0 1.6 0.002 17.8 1.1 2.3 1 0 0 1 1 1 1 F-box-like DUF3296 PF11726.3 OAJ12513.1 - 0.027 14.0 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) F-box PF00646.28 OAJ12513.1 - 0.042 13.5 0.1 0.33 10.6 0.1 2.5 2 0 0 2 2 2 0 F-box domain tRNA_anti-codon PF01336.20 OAJ12515.1 - 0.38 10.6 3.1 0.74 9.7 0.5 2.2 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain 3Beta_HSD PF01073.14 OAJ12523.1 - 3.5e-16 58.7 0.0 3.5e-15 55.4 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAJ12523.1 - 1.3e-14 54.2 0.1 3.3e-14 52.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ12523.1 - 6.6e-13 49.0 0.0 1.2e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 OAJ12523.1 - 4.9e-08 32.5 0.0 6.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 OAJ12523.1 - 8.6e-08 31.4 0.1 7.4e-07 28.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 OAJ12523.1 - 1.3e-05 24.2 0.0 2.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 OAJ12523.1 - 3.4e-05 23.8 0.5 0.00011 22.1 0.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ12523.1 - 0.0026 17.4 0.7 0.062 12.9 0.5 2.4 1 1 0 1 1 1 1 KR domain NAD_binding_2 PF03446.10 OAJ12523.1 - 0.0079 16.0 0.0 0.023 14.5 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 OAJ12523.1 - 0.031 13.6 0.1 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ribosomal_S21 PF01165.15 OAJ12524.1 - 2.5e-11 42.8 3.9 5.1e-11 41.8 2.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 Complex1_LYR_2 PF13233.1 OAJ12525.1 - 1e-11 45.2 0.0 1.8e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 Complex1_LYR-like HTH_28 PF13518.1 OAJ12525.1 - 0.12 12.3 0.1 4 7.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Ribosomal_60s PF00428.14 OAJ12525.1 - 0.72 10.2 4.1 0.34 11.3 0.7 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein UFD1 PF03152.9 OAJ12526.1 - 4.1e-64 214.9 0.0 5.3e-64 214.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 OAJ12526.1 - 0.27 10.8 1.6 3 7.5 0.0 2.7 2 1 1 3 3 3 0 Cell division protein 48 (CDC48), domain 2 LRR_4 PF12799.2 OAJ12527.1 - 0.00082 18.9 2.9 5 6.8 0.0 4.9 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 OAJ12527.1 - 0.00096 18.9 12.9 9.8 6.5 0.7 7.6 7 1 0 7 7 7 1 Leucine Rich repeat LRR_8 PF13855.1 OAJ12527.1 - 0.001 18.7 1.6 2.5 7.9 0.0 4.7 4 1 0 4 4 4 1 Leucine rich repeat Vac7 PF12751.2 OAJ12527.1 - 0.098 11.4 7.5 0.19 10.5 5.2 1.4 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 LRR_7 PF13504.1 OAJ12527.1 - 0.16 12.2 3.4 49 4.7 0.0 5.2 5 0 0 5 5 5 0 Leucine rich repeat UDPGT PF00201.13 OAJ12528.1 - 4.4e-08 32.1 0.0 1.2e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 OAJ12528.1 - 0.00044 20.0 0.2 0.0012 18.6 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_4_2 PF13477.1 OAJ12528.1 - 0.013 15.3 0.0 4 7.2 0.0 2.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like Put_Phosphatase PF06888.7 OAJ12529.1 - 2.1e-50 171.1 0.0 2.6e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase adh_short_C2 PF13561.1 OAJ12530.1 - 2.8e-30 105.8 0.0 3.4e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ12530.1 - 5.7e-19 68.6 0.8 2e-18 66.8 0.7 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAJ12530.1 - 2.6e-08 33.7 0.1 3.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 KR domain PA PF02225.17 OAJ12530.1 - 0.031 13.9 0.6 0.086 12.5 0.0 1.9 2 0 0 2 2 2 0 PA domain Saccharop_dh PF03435.13 OAJ12530.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase HEAT_EZ PF13513.1 OAJ12548.1 - 5.5e-16 58.5 1.8 2.4e-06 27.8 0.0 5.6 5 1 1 6 6 6 5 HEAT-like repeat HEAT PF02985.17 OAJ12548.1 - 2.6e-14 51.9 0.8 5.9e-05 22.8 0.1 4.7 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.1 OAJ12548.1 - 2.4e-09 37.3 2.0 1.6e-05 25.1 0.0 3.7 2 1 2 4 4 4 3 HEAT repeats Arm PF00514.18 OAJ12548.1 - 0.0022 17.7 1.5 29 4.6 0.0 5.3 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 OAJ12548.1 - 0.018 15.4 0.1 4.9 7.6 0.0 3.0 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.2 OAJ12548.1 - 0.035 14.0 0.0 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion MMS19_C PF12460.3 OAJ12548.1 - 0.041 12.6 0.0 3.6 6.2 0.2 2.3 1 1 1 2 2 2 0 RNAPII transcription regulator C-terminal Adaptin_N PF01602.15 OAJ12548.1 - 0.05 11.9 0.7 1.5 7.0 0.0 3.0 1 1 1 2 2 2 0 Adaptin N terminal region Cytochrom_NNT PF03264.9 OAJ12552.1 - 0.048 13.1 0.5 0.077 12.4 0.1 1.5 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region zf-C3HC4_2 PF13923.1 OAJ12554.1 - 2.1e-06 27.6 1.0 3e-06 27.1 0.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ12554.1 - 3.6e-06 26.5 0.9 5.2e-06 26.0 0.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Pex2_Pex12 PF04757.9 OAJ12554.1 - 0.00052 19.5 0.5 0.00073 19.0 0.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region FdhE PF04216.7 OAJ12554.1 - 0.0023 17.6 0.2 0.0029 17.4 0.1 1.1 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation zf-RING_2 PF13639.1 OAJ12554.1 - 0.15 11.8 2.2 0.35 10.7 1.5 1.6 1 1 1 2 2 2 0 Ring finger domain tRNA-synt_1 PF00133.17 OAJ12555.1 - 2.3e-06 25.9 0.0 2.5e-06 25.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 OAJ12555.1 - 0.013 14.8 0.0 0.015 14.5 0.0 1.0 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 PCI PF01399.22 OAJ12564.1 - 2.6e-05 24.4 0.0 5.5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain LRR_6 PF13516.1 OAJ12565.1 - 0.077 13.1 4.6 63 4.1 0.0 5.5 5 0 0 5 5 5 0 Leucine Rich repeat Pox_Ag35 PF03286.9 OAJ12568.1 - 0.031 13.8 16.2 0.04 13.4 3.1 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF1754 PF08555.5 OAJ12568.1 - 0.54 10.8 22.6 0.2 12.2 8.1 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Cwf_Cwc_15 PF04889.7 OAJ12568.1 - 0.8 9.3 23.7 0.99 9.0 8.6 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DDHD PF02862.12 OAJ12568.1 - 0.95 9.2 11.3 2.4 7.8 1.9 2.0 2 0 0 2 2 2 0 DDHD domain DUF1510 PF07423.6 OAJ12568.1 - 3.3 7.0 20.1 0.4 10.0 6.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) GAS PF13851.1 OAJ12568.1 - 5.4 6.1 18.1 0.035 13.3 7.0 1.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2968 PF11180.3 OAJ12568.1 - 7.4 5.8 13.8 11 5.3 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) KASH PF10541.4 OAJ12569.1 - 2.3 8.1 6.0 4.8 7.1 4.2 1.5 1 1 0 1 1 1 0 Nuclear envelope localisation domain CIAPIN1 PF05093.8 OAJ12577.1 - 8.4e-31 106.0 3.5 1.9e-30 104.8 2.4 1.6 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis rve PF00665.21 OAJ12578.1 - 2.4e-19 69.5 0.0 8.8e-19 67.7 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ12578.1 - 3.7e-15 55.8 0.0 9.3e-15 54.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 OAJ12578.1 - 0.00042 20.1 8.0 0.00042 20.1 5.6 2.2 3 0 0 3 3 3 1 Zinc knuckle rve_3 PF13683.1 OAJ12578.1 - 0.0085 15.5 0.0 0.025 14.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain PX PF00787.19 OAJ12590.1 - 1.2e-23 83.0 0.1 1.2e-23 83.0 0.1 1.8 2 0 0 2 2 2 1 PX domain PAT1 PF09770.4 OAJ12590.1 - 0.00032 19.1 55.0 0.00039 18.8 38.1 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 OAJ12590.1 - 0.077 11.1 66.6 0.12 10.6 46.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SAGA-Tad1 PF12767.2 OAJ12590.1 - 0.55 9.8 18.2 0.97 9.0 12.6 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit ABC_tran PF00005.22 OAJ12591.1 - 2.2e-08 34.4 0.1 1.2e-07 32.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC_trans_N PF14510.1 OAJ12591.1 - 1.1e-07 31.8 0.1 1.6e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal FtsK_SpoIIIE PF01580.13 OAJ12591.1 - 0.055 12.9 0.2 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 OAJ12591.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 OAJ12591.1 - 0.085 13.6 0.0 0.17 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 OAJ12591.1 - 0.15 12.0 0.1 2.6 7.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Sds3 PF08598.6 OAJ12592.1 - 3.6e-10 39.7 10.2 3.6e-10 39.7 7.1 2.4 2 0 0 2 2 2 1 Sds3-like Ycf1 PF05758.7 OAJ12592.1 - 0.0012 16.6 0.0 0.51 7.9 0.3 2.0 2 0 0 2 2 2 2 Ycf1 Hid1 PF12722.2 OAJ12592.1 - 0.54 7.8 8.5 1 6.9 5.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Baculo_PP31 PF05311.6 OAJ12592.1 - 4.5 6.4 23.0 0.03 13.6 1.2 2.4 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Peptidase_M16_C PF05193.16 OAJ12593.1 - 0.063 12.9 1.2 0.14 11.8 0.4 2.0 2 0 0 2 2 2 0 Peptidase M16 inactive domain DUF2360 PF10152.4 OAJ12593.1 - 0.98 9.6 6.9 0.98 9.6 2.8 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Peptidase_C12 PF01088.16 OAJ12594.1 - 1.9e-56 190.6 0.0 2.1e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Utp12 PF04003.7 OAJ12595.1 - 9.8e-10 38.3 2.1 6.3e-08 32.4 0.5 2.4 2 0 0 2 2 2 2 Dip2/Utp12 Family Sec63 PF02889.11 OAJ12596.1 - 2.7e-31 108.9 0.0 5.3e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 OAJ12596.1 - 1.6e-16 59.8 0.3 3.2e-16 58.8 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DUF2305 PF10230.4 OAJ12596.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Striatin PF08232.7 OAJ12605.1 - 0.98 9.7 16.1 0.012 15.9 3.6 2.6 2 0 0 2 2 2 0 Striatin family SWIM PF04434.12 OAJ12606.1 - 8.4e-06 25.1 0.4 1.7e-05 24.1 0.3 1.4 1 0 0 1 1 1 1 SWIM zinc finger DDE_Tnp_IS240 PF13610.1 OAJ12606.1 - 0.11 12.5 0.3 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 DDE domain DUF3844 PF12955.2 OAJ12607.1 - 7.6e-26 90.2 0.2 1.4e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 OAJ12607.1 - 0.17 12.0 2.8 0.37 11.0 1.9 1.5 1 0 0 1 1 1 0 EGF-like domain CoA_binding PF02629.14 OAJ12608.1 - 1.1e-28 99.5 1.9 3e-27 94.9 0.1 2.5 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 OAJ12608.1 - 1e-19 70.6 0.6 2.2e-19 69.5 0.4 1.6 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 OAJ12608.1 - 8.7e-09 35.1 0.1 1.9e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 OAJ12608.1 - 7.9e-05 22.8 0.0 0.00042 20.4 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 OAJ12608.1 - 0.0025 18.3 0.0 0.0065 16.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Prefoldin_2 PF01920.15 OAJ12609.1 - 5.2e-23 80.8 0.6 6.2e-23 80.5 0.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.10 OAJ12609.1 - 5.5e-05 22.5 2.2 0.083 12.3 0.0 2.2 1 1 1 2 2 2 2 Septum formation initiator FTA4 PF13093.1 OAJ12609.1 - 0.0011 18.5 0.2 0.0013 18.2 0.2 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 ADIP PF11559.3 OAJ12609.1 - 0.0068 16.3 1.5 2.5 8.0 0.0 2.1 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding Spc24 PF08286.6 OAJ12609.1 - 0.016 14.8 5.7 0.62 9.7 1.3 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin PF02996.12 OAJ12609.1 - 0.024 14.2 0.9 0.069 12.8 0.6 1.6 1 1 0 1 1 1 0 Prefoldin subunit Atg14 PF10186.4 OAJ12609.1 - 0.03 13.2 0.2 0.038 12.9 0.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NIT PF08376.5 OAJ12609.1 - 0.033 13.7 0.3 0.083 12.4 0.1 1.6 2 0 0 2 2 2 0 Nitrate and nitrite sensing STAT_alpha PF01017.15 OAJ12609.1 - 0.057 13.1 1.3 0.3 10.7 0.9 1.9 1 1 0 1 1 1 0 STAT protein, all-alpha domain TMF_DNA_bd PF12329.3 OAJ12609.1 - 0.059 13.1 1.6 1.5 8.6 0.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 OAJ12609.1 - 0.069 13.0 1.1 1.1 9.1 0.1 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) PEP-utilisers_N PF05524.8 OAJ12609.1 - 0.087 12.6 0.7 0.84 9.4 0.0 2.0 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF869 PF05911.6 OAJ12609.1 - 0.096 10.9 2.8 0.38 8.9 0.1 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) Seryl_tRNA_N PF02403.17 OAJ12609.1 - 0.12 12.3 2.3 3.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4164 PF13747.1 OAJ12609.1 - 0.17 12.0 4.6 3.1 7.9 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TPR_MLP1_2 PF07926.7 OAJ12609.1 - 0.19 11.4 1.8 7 6.4 0.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF465 PF04325.8 OAJ12609.1 - 0.32 10.7 2.9 1.7 8.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF465) CCDC-167 PF15188.1 OAJ12609.1 - 0.4 10.6 3.0 6.6 6.7 0.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 HalX PF08663.5 OAJ12609.1 - 0.53 10.2 5.1 0.31 11.0 1.1 2.2 2 0 0 2 2 2 0 HalX domain Cytadhesin_P30 PF07271.6 OAJ12610.1 - 2.3 7.4 4.5 3.2 6.9 3.1 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF2630 PF10944.3 OAJ12625.1 - 0.11 12.5 0.1 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Helicase_C PF00271.26 OAJ12636.1 - 6.1e-12 45.2 0.0 1.4e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ12636.1 - 8.9e-11 41.5 0.0 1.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ12636.1 - 0.00052 19.8 0.0 0.00087 19.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Phage_integrase PF00589.17 OAJ12636.1 - 0.12 12.0 0.0 12 5.5 0.0 2.4 2 0 0 2 2 2 0 Phage integrase family DUF2973 PF11189.3 OAJ12637.1 - 0.01 15.5 0.0 0.033 13.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) Guanylate_cyc_2 PF09778.4 OAJ12637.1 - 0.027 13.6 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Guanylylate cyclase Abhydrolase_5 PF12695.2 OAJ12638.1 - 0.00079 19.1 0.0 0.0039 16.9 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Nup35_RRM PF05172.8 OAJ12638.1 - 0.036 13.8 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PGAP1 PF07819.8 OAJ12638.1 - 0.043 13.4 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein ASFV_L11L PF05293.6 OAJ12638.1 - 2 8.6 3.9 0.65 10.1 0.1 2.2 3 0 0 3 3 3 0 African swine fever virus (ASFV) L11L protein MULE PF10551.4 OAJ12651.1 - 1.1e-17 63.9 0.0 2.9e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ12651.1 - 1.2e-13 50.4 0.0 2.6e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Transposase, Mutator family SWIM PF04434.12 OAJ12651.1 - 1.4e-05 24.4 0.4 3.6e-05 23.1 0.3 1.6 1 0 0 1 1 1 1 SWIM zinc finger FAR1 PF03101.10 OAJ12651.1 - 0.00011 22.5 0.0 0.00026 21.4 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain DDE_Tnp_IS240 PF13610.1 OAJ12651.1 - 0.00071 19.5 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 DDE domain rve PF00665.21 OAJ12651.1 - 0.03 14.4 0.0 0.075 13.1 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain DDE_Tnp_ISL3 PF01610.12 OAJ12651.1 - 0.16 11.5 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Transposase FAD_binding_1 PF00667.15 OAJ12652.1 - 8.2e-30 103.8 0.0 1.3e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 OAJ12652.1 - 1.2e-23 83.6 0.0 3.1e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 OAJ12652.1 - 5.8e-08 33.2 0.0 1.5e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 OAJ12652.1 - 0.005 16.8 0.0 0.0089 16.0 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.2 OAJ12652.1 - 0.097 12.0 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Flavodoxin domain BLOC1_2 PF10046.4 OAJ12653.1 - 0.025 14.6 2.6 0.039 14.0 1.8 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 OAJ12653.1 - 0.43 9.5 8.3 0.54 9.2 5.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 HSP70 PF00012.15 OAJ12653.1 - 1.6 6.5 7.6 1.9 6.2 5.3 1.0 1 0 0 1 1 1 0 Hsp70 protein XkdW PF09636.5 OAJ12653.1 - 2.2 8.1 8.1 1 9.2 1.8 2.1 1 1 1 2 2 2 0 XkdW protein AMP-binding PF00501.23 OAJ12663.1 - 1.4e-28 99.4 0.0 1e-27 96.6 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 OAJ12663.1 - 5e-24 84.5 0.0 9.7e-24 83.6 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 OAJ12663.1 - 1.4e-09 38.0 0.1 2.6e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 OAJ12663.1 - 1.3e-07 31.2 0.0 2.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 OAJ12663.1 - 0.0038 16.9 0.5 0.042 13.5 0.4 2.4 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 OAJ12663.1 - 0.017 15.0 1.1 0.15 11.9 0.8 2.4 1 1 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 OAJ12663.1 - 0.15 12.3 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 OAJ12663.1 - 0.28 10.0 0.0 0.5 9.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Aldo_ket_red PF00248.16 OAJ12664.1 - 2.3e-63 213.6 0.0 2.9e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ADK PF00406.17 OAJ12665.1 - 2.1e-44 151.0 0.0 9.8e-24 83.9 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase AAA_18 PF13238.1 OAJ12665.1 - 1.1e-11 45.1 0.0 2.1e-11 44.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 OAJ12665.1 - 1.3e-07 31.1 0.2 0.0021 17.4 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_17 PF13207.1 OAJ12665.1 - 1.1e-06 29.4 0.0 1.8e-06 28.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ12665.1 - 5e-05 23.2 0.0 0.00062 19.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ12665.1 - 0.048 13.4 0.1 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain Snf7 PF03357.16 OAJ12666.1 - 1.3e-38 132.0 15.6 2e-38 131.4 10.8 1.3 1 0 0 1 1 1 1 Snf7 TPR_MLP1_2 PF07926.7 OAJ12666.1 - 0.001 18.8 6.1 0.0015 18.2 4.2 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.7 OAJ12666.1 - 0.044 13.1 16.6 0.1 11.9 3.9 2.1 1 1 1 2 2 2 0 PspA/IM30 family YlqD PF11068.3 OAJ12666.1 - 0.38 10.7 12.7 3 7.8 8.8 2.1 1 1 0 1 1 1 0 YlqD protein MULE PF10551.4 OAJ12667.1 - 5.3e-17 61.7 0.1 1.3e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ12667.1 - 1.8e-05 23.4 0.6 0.00036 19.2 0.1 2.1 2 0 0 2 2 2 2 Transposase, Mutator family Methyltransf_3 PF01596.12 OAJ12668.1 - 1.6e-52 177.5 0.0 2.2e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 OAJ12668.1 - 3.3e-12 47.1 0.0 5.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ12668.1 - 2.8e-07 30.5 0.0 5.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ12668.1 - 0.0011 19.5 0.0 0.0021 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 OAJ12668.1 - 0.044 13.3 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-CHCC PF10276.4 OAJ12669.1 - 9.9e-18 63.7 1.1 1.5e-17 63.1 0.8 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 OAJ12669.1 - 0.002 17.8 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb DUF605 PF04652.11 OAJ12669.1 - 0.0057 16.1 6.9 0.0063 15.9 4.8 1.0 1 0 0 1 1 1 1 Vta1 like Mito_carr PF00153.22 OAJ12683.1 - 2.5e-47 158.5 0.0 2.3e-15 56.0 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein TrkH PF02386.11 OAJ12684.1 - 1.6e-87 293.4 14.7 4.4e-86 288.6 3.6 2.1 2 0 0 2 2 2 2 Cation transport protein CytochromB561_N PF09786.4 OAJ12684.1 - 0.01 14.3 0.1 0.016 13.6 0.1 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal ERO1 PF04137.10 OAJ12685.1 - 2.7e-117 391.7 0.0 1.8e-115 385.7 0.0 2.1 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) LCAT PF02450.10 OAJ12686.1 - 6e-82 275.6 0.1 1.1e-81 274.7 0.1 1.4 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF2523 PF10734.4 OAJ12686.1 - 0.2 11.9 1.7 0.44 10.8 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2523) DUF1275 PF06912.6 OAJ12687.1 - 8e-25 87.2 14.8 1e-24 86.8 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) YibE_F PF07907.6 OAJ12687.1 - 0.1 11.7 9.2 0.21 10.7 5.5 1.9 1 1 0 1 1 1 0 YibE/F-like protein ATP-grasp_2 PF08442.5 OAJ12688.1 - 3.9e-68 228.8 0.1 6.6e-68 228.0 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 OAJ12688.1 - 2e-23 82.7 0.8 3.6e-23 81.8 0.5 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 OAJ12688.1 - 3.1e-12 46.2 0.1 5.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 OAJ12688.1 - 0.001 18.7 0.1 0.0025 17.3 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.12 OAJ12688.1 - 0.025 13.8 0.1 0.065 12.5 0.0 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 OAJ12688.1 - 0.053 13.2 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.17 OAJ12688.1 - 0.062 12.6 0.1 0.18 11.1 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain HipA_N PF07805.7 OAJ12688.1 - 0.077 13.2 0.1 1.6 9.0 0.0 2.8 2 0 0 2 2 2 0 HipA-like N-terminal domain Leo1 PF04004.8 OAJ12702.1 - 0.093 12.4 0.3 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 Leo1-like protein Transposase_21 PF02992.9 OAJ12703.1 - 0.00097 18.2 0.0 0.0022 17.1 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 Daxx PF03344.10 OAJ12704.1 - 0.004 15.7 3.9 0.0054 15.2 2.7 1.1 1 0 0 1 1 1 1 Daxx Family SURF2 PF05477.6 OAJ12704.1 - 0.027 13.6 5.1 0.048 12.7 3.6 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.9 OAJ12704.1 - 0.21 9.5 4.5 0.34 8.8 3.1 1.3 1 0 0 1 1 1 0 CDC45-like protein ABC_membrane_3 PF13748.1 OAJ12714.1 - 0.075 12.0 0.6 0.14 11.1 0.4 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region TPR_12 PF13424.1 OAJ12715.1 - 4.6e-18 64.9 7.7 3.4e-09 36.4 2.3 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ12715.1 - 3e-11 42.8 5.5 0.0013 18.5 0.9 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ12715.1 - 1.5e-07 30.8 4.0 0.0079 16.0 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ12715.1 - 1.1e-06 28.1 5.1 0.0025 17.4 1.6 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 OAJ12715.1 - 9.9e-05 21.7 0.1 0.15 11.7 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ12715.1 - 0.00052 20.6 5.8 0.046 14.4 0.6 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.2 OAJ12715.1 - 0.00076 19.3 2.0 0.069 12.9 0.5 2.5 1 1 1 2 2 2 2 Domain of Unknown Function (DUF3856) TPR_14 PF13428.1 OAJ12715.1 - 0.0012 19.3 7.5 0.67 10.7 0.2 4.4 5 1 0 5 5 4 2 Tetratricopeptide repeat Apc5 PF12862.2 OAJ12715.1 - 0.0024 17.6 1.1 1.9 8.3 0.0 3.1 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 5 TPR_8 PF13181.1 OAJ12715.1 - 0.0059 16.3 5.4 7.2 6.6 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 OAJ12715.1 - 0.012 15.7 2.2 0.97 9.6 0.5 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 OAJ12715.1 - 0.017 14.2 3.6 6.1 5.8 0.0 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ12715.1 - 0.028 14.2 2.6 1.9 8.4 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ12715.1 - 0.036 14.2 0.3 75 3.9 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ12715.1 - 0.037 14.5 2.2 23 5.7 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.12 OAJ12715.1 - 0.17 12.2 5.9 2.5 8.4 0.1 3.8 2 2 1 4 4 4 0 Bacterial transcriptional activator domain TPR_4 PF07721.9 OAJ12715.1 - 0.2 12.1 3.8 31 5.3 0.0 4.5 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ12715.1 - 0.23 11.8 4.0 24 5.3 0.2 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat HA2 PF04408.18 OAJ12716.1 - 6.9e-15 54.9 0.0 2.3e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ12716.1 - 7.2e-14 51.4 0.1 1.5e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ12716.1 - 1.1e-09 38.0 0.0 4.3e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ12716.1 - 9.5e-05 22.5 0.0 0.00031 20.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 OAJ12716.1 - 0.049 12.7 0.1 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 KaiC ResIII PF04851.10 OAJ12716.1 - 0.33 10.7 0.0 0.76 9.5 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit IMS PF00817.15 OAJ12717.1 - 3.8e-39 133.8 0.0 9.8e-39 132.5 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 OAJ12717.1 - 2.3e-14 53.4 0.0 5.8e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 OAJ12717.1 - 6.9e-07 29.1 0.1 0.031 14.1 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) AAA_5 PF07728.9 OAJ12728.1 - 3.1e-37 127.4 0.0 9e-29 99.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) TENA_THI-4 PF03070.11 OAJ12742.1 - 7.5e-09 35.6 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family DUF370 PF04025.7 OAJ12743.1 - 0.073 13.1 0.3 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF370) Ribosomal_S8 PF00410.14 OAJ12754.1 - 1.9e-23 82.6 0.0 2.6e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.13 OAJ12755.1 - 8.4e-58 193.4 0.0 1e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal S17 Ribosom_S12_S23 PF00164.20 OAJ12756.1 - 3.2e-45 152.4 0.1 4.2e-45 152.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PBP1_TM PF14812.1 OAJ12757.1 - 2.3 8.5 5.6 0.69 10.2 0.2 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 OAJ12773.1 - 4.9e-70 229.1 10.3 1.4e-11 43.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 OAJ12773.1 - 1.3e-18 66.9 0.8 1.3e-18 66.9 0.6 2.5 2 0 0 2 2 2 1 Tup N-terminal PD40 PF07676.7 OAJ12773.1 - 0.0013 18.3 0.1 39 4.0 0.0 5.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF1777 PF08648.7 OAJ12773.1 - 0.0083 15.8 34.8 0.0083 15.8 24.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1777) Nup160 PF11715.3 OAJ12773.1 - 0.015 13.4 0.3 3.7 5.5 0.0 2.7 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAJ12773.1 - 0.022 13.5 0.2 0.63 8.7 0.0 2.8 1 1 2 3 3 3 0 Nup133 N terminal like Cytochrom_D1 PF02239.11 OAJ12773.1 - 0.088 11.0 0.1 0.29 9.3 0.0 1.9 1 1 0 1 1 1 0 Cytochrome D1 heme domain PRP38_assoc PF12871.2 OAJ12773.1 - 0.11 12.9 38.0 0.019 15.4 23.1 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term tRNA-synt_2b PF00587.20 OAJ12787.1 - 7.9e-17 61.3 0.0 7.5e-16 58.1 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) AATF-Che1 PF13339.1 OAJ12787.1 - 0.16 12.1 0.8 0.36 10.9 0.6 1.6 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor AA_permease PF00324.16 OAJ12790.1 - 1.4e-117 392.9 37.7 1.6e-117 392.8 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAJ12790.1 - 4.4e-35 121.0 43.6 5.5e-35 120.7 30.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 OAJ12790.1 - 0.061 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) HhH-GPD PF00730.20 OAJ12791.1 - 5e-10 39.6 0.0 1.1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DPM3 PF08285.6 OAJ12792.1 - 6.1e-27 93.2 0.0 6.8e-27 93.1 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) ATG_C PF09333.6 OAJ12793.1 - 3.8e-26 91.0 0.5 1.2e-25 89.5 0.1 2.0 2 0 0 2 2 2 1 ATG C terminal domain Fib_alpha PF08702.5 OAJ12793.1 - 0.0028 17.8 0.2 0.0053 16.8 0.1 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family eIF-1a PF01176.14 OAJ12794.1 - 5.8e-28 96.1 0.1 8.2e-28 95.6 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Tubulin_3 PF14881.1 OAJ12804.1 - 2.4e-28 98.8 13.5 4.3e-19 68.6 1.2 4.3 2 1 1 3 3 3 3 Tubulin domain Misat_Tub_SegII PF10644.4 OAJ12804.1 - 7.5e-26 90.4 0.0 3.1e-25 88.4 0.0 2.1 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Toxin_29 PF08116.6 OAJ12805.1 - 0.26 11.1 0.0 0.26 11.1 0.0 5.5 5 1 1 6 6 6 0 PhTx neurotoxin family Colipase-like PF15083.1 OAJ12805.1 - 1.4 8.9 26.0 2.8 7.9 0.0 4.1 2 1 3 5 5 5 0 Colipase-like zf-Sec23_Sec24 PF04810.10 OAJ12806.1 - 0.11 12.1 0.2 0.23 11.0 0.2 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger MT-A70 PF05063.9 OAJ12808.1 - 9.5e-49 165.3 0.0 7.7e-33 113.5 0.0 2.2 2 0 0 2 2 2 2 MT-A70 Methyltransf_26 PF13659.1 OAJ12808.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain zf-CCHC_6 PF15288.1 OAJ12809.1 - 0.013 15.1 0.6 0.041 13.5 0.4 1.8 1 0 0 1 1 1 0 Zinc knuckle HHH PF00633.18 OAJ12822.1 - 0.023 14.3 0.8 0.041 13.5 0.1 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF2647 PF10839.3 OAJ12822.1 - 0.28 11.3 1.0 0.65 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2647) HHH_5 PF14520.1 OAJ12822.1 - 1.3 9.2 4.8 3.9 7.7 0.7 3.1 2 1 1 3 3 3 0 Helix-hairpin-helix domain HCNGP PF07818.8 OAJ12824.1 - 4.5e-05 23.3 0.0 7.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein FAM220 PF15487.1 OAJ12824.1 - 0.043 13.1 8.0 0.03 13.7 4.6 1.4 1 1 0 1 1 1 0 FAM220 family Apolipoprotein PF01442.13 OAJ12825.1 - 0.0007 19.1 10.9 0.002 17.6 7.6 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain HAUS-augmin3 PF14932.1 OAJ12825.1 - 0.0014 17.8 5.9 0.0014 17.8 4.1 1.3 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 3 Baculo_PEP_C PF04513.7 OAJ12825.1 - 0.016 15.0 6.9 0.11 12.3 1.7 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hemerythrin PF01814.18 OAJ12825.1 - 0.088 12.9 3.8 0.67 10.1 0.1 2.1 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain SF-assemblin PF06705.6 OAJ12825.1 - 0.093 11.8 2.0 0.14 11.2 1.4 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin Exonuc_VII_L PF02601.10 OAJ12825.1 - 0.12 11.5 2.9 0.15 11.2 2.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1640 PF07798.6 OAJ12825.1 - 0.17 11.9 5.3 1.2 9.1 3.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Bacillus_HBL PF05791.6 OAJ12825.1 - 0.2 11.0 4.2 0.16 11.3 1.4 1.8 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Snapin_Pallidin PF14712.1 OAJ12825.1 - 0.2 11.9 4.6 0.28 11.5 2.4 1.9 1 1 0 1 1 1 0 Snapin/Pallidin DUF4164 PF13747.1 OAJ12825.1 - 0.53 10.4 3.5 0.95 9.6 2.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Fzo_mitofusin PF04799.8 OAJ12825.1 - 2.9 7.2 7.8 1.4 8.3 2.1 2.4 1 1 2 3 3 3 0 fzo-like conserved region FlxA PF14282.1 OAJ12825.1 - 3.2 7.7 9.4 4.3 7.3 6.2 1.5 1 1 0 1 1 1 0 FlxA-like protein OmpH PF03938.9 OAJ12825.1 - 6.3 6.7 9.5 14 5.5 6.6 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) PIF1 PF05970.9 OAJ12826.1 - 1.8e-22 79.8 0.0 2.2e-21 76.2 0.0 2.1 2 0 0 2 2 2 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ12826.1 - 1.6e-11 44.2 0.1 4e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 OAJ12826.1 - 8.2e-10 38.5 0.0 3.4e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ12826.1 - 1.5e-07 31.0 1.7 2.7e-06 27.0 0.1 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 OAJ12826.1 - 0.0021 18.0 0.1 0.015 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 OAJ12826.1 - 0.048 13.3 0.1 0.18 11.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Torsin PF06309.6 OAJ12826.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.21 OAJ12826.1 - 0.066 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF605 PF04652.11 OAJ12839.1 - 0.84 8.9 8.8 1.2 8.4 6.1 1.1 1 0 0 1 1 1 0 Vta1 like DNA_pol_viral_N PF00242.12 OAJ12839.1 - 2.6 6.9 4.9 3.5 6.5 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain ABC_tran PF00005.22 OAJ12840.1 - 1.6e-15 57.6 0.1 2e-13 50.8 0.0 3.3 2 2 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 OAJ12840.1 - 6.5e-08 32.8 2.5 0.0048 16.9 0.2 3.1 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 OAJ12840.1 - 9.8e-07 28.6 0.0 0.013 15.3 0.0 2.8 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 OAJ12840.1 - 0.00037 20.8 0.2 0.00067 20.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 OAJ12840.1 - 0.0021 17.5 0.1 0.004 16.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 OAJ12840.1 - 0.016 14.5 0.1 0.17 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 OAJ12840.1 - 0.023 13.9 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit SMC_N PF02463.14 OAJ12840.1 - 0.025 13.7 0.1 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Guanylate_kin PF00625.16 OAJ12840.1 - 0.037 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA_19 PF13245.1 OAJ12840.1 - 0.041 13.6 0.1 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 OAJ12840.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 OAJ12840.1 - 0.14 11.0 0.1 0.37 9.6 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF258 PF03193.11 OAJ12840.1 - 0.17 11.0 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_15 PF13175.1 OAJ12840.1 - 0.17 10.8 0.0 0.38 9.7 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain CRAL_TRIO PF00650.15 OAJ12841.1 - 4.2e-29 101.0 0.0 7.8e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ12841.1 - 5.7e-09 35.9 0.5 1.9e-08 34.2 0.4 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain AMPKBI PF04739.10 OAJ12842.1 - 9.1e-27 92.8 0.0 1.6e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain Pkinase PF00069.20 OAJ12855.1 - 2.4e-06 26.9 0.0 3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 OAJ12855.1 - 4.8e-05 22.5 0.0 7.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ12855.1 - 0.0018 18.0 0.1 0.0025 17.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 OAJ12855.1 - 0.0033 16.5 0.0 0.0065 15.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 OAJ12855.1 - 0.16 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CorA PF01544.13 OAJ12856.1 - 3e-45 154.4 0.2 4.1e-45 154.0 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ACT_4 PF13291.1 OAJ12856.1 - 0.15 12.3 0.1 0.38 11.1 0.1 1.6 1 0 0 1 1 1 0 ACT domain GHMP_kinases_N PF00288.21 OAJ12857.1 - 1.6e-12 47.2 2.3 5.5e-12 45.5 1.6 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 OAJ12857.1 - 0.0019 18.3 0.0 0.0052 16.9 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Pkinase PF00069.20 OAJ12859.1 - 8.8e-05 21.7 0.0 0.00015 20.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ12859.1 - 0.00079 18.5 0.0 0.0015 17.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase BPL_LplA_LipB PF03099.14 OAJ12860.1 - 7.5e-11 42.1 0.0 1.3e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Pkinase PF00069.20 OAJ12861.1 - 1.4e-05 24.3 0.0 1.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 OAJ12861.1 - 0.00025 20.1 0.0 0.00034 19.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 OAJ12861.1 - 0.014 14.4 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 OAJ12861.1 - 0.021 14.5 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ATP-synt_ab PF00006.20 OAJ12875.1 - 1.1e-05 25.1 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain RRM_1 PF00076.17 OAJ12876.1 - 3e-27 94.0 0.3 2.1e-16 59.2 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ12876.1 - 7.5e-15 54.6 0.0 4.7e-10 39.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ12876.1 - 3.3e-12 46.0 0.0 4.9e-10 39.1 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ12876.1 - 0.0001 22.0 0.0 0.0001 22.0 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 OAJ12876.1 - 0.0015 18.2 0.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Cellulose_synt PF03552.9 OAJ12876.1 - 4 5.6 6.1 5.8 5.0 4.2 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF648 PF04890.8 OAJ12876.1 - 9.3 5.3 17.1 14 4.6 11.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) Suf PF05843.9 OAJ12876.1 - 9.9 5.7 28.9 7.5 6.1 13.6 2.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) UPF0061 PF02696.9 OAJ12877.1 - 4e-07 28.7 0.1 5.4e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family He_PIG PF05345.7 OAJ12878.1 - 8e-14 51.3 11.5 1.9e-05 24.5 0.1 4.1 3 0 0 3 3 3 3 Putative Ig domain Clathrin_H_link PF13838.1 OAJ12878.1 - 0.1 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Clathrin-H-link CAF-1_p150 PF11600.3 OAJ12893.1 - 0.11 11.8 15.4 0.18 11.1 10.6 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Glyco_hydro_47 PF01532.15 OAJ12894.1 - 2.9e-147 490.9 0.0 3.4e-147 490.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Myb_DNA-bind_4 PF13837.1 OAJ12895.1 - 0.04 14.0 0.1 0.04 14.0 0.1 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.1 OAJ12896.1 - 1.2e-21 76.9 0.8 2e-21 76.2 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF515 PF04415.7 OAJ12896.1 - 5.3 5.1 7.6 8.1 4.5 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ATG16 PF08614.6 OAJ12897.1 - 0.00094 19.0 5.8 0.0019 18.0 4.0 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Macoilin PF09726.4 OAJ12897.1 - 0.12 10.5 7.5 0.22 9.7 5.2 1.5 1 0 0 1 1 1 0 Transmembrane protein TauD PF02668.11 OAJ12898.1 - 2.5e-47 161.7 1.7 3.1e-47 161.4 1.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 OAJ12898.1 - 0.063 13.7 0.3 0.77 10.3 0.1 2.5 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily Carn_acyltransf PF00755.15 OAJ12899.1 - 9.3e-128 426.8 0.0 2.4e-127 425.5 0.0 1.7 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase DDE_1 PF03184.14 OAJ12917.1 - 1.5e-06 27.5 0.0 1.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease SSP160 PF06933.6 OAJ12921.1 - 1.6 6.6 14.1 2 6.2 9.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TFIIA PF03153.8 OAJ12921.1 - 3.3 7.4 5.1 3.8 7.3 3.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Afi1 PF07792.7 OAJ12922.1 - 4.5 7.2 8.7 4.2 7.3 5.3 1.5 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking OB_NTP_bind PF07717.11 OAJ12930.1 - 3.1e-25 88.2 0.0 6.5e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 OAJ12930.1 - 2.7e-21 75.4 0.0 5.9e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ12930.1 - 6.6e-15 54.7 0.0 1.3e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ12930.1 - 3.2e-05 23.4 0.0 7.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ12930.1 - 7e-05 22.9 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 OAJ12930.1 - 0.01 15.7 0.0 0.09 12.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 OAJ12930.1 - 0.1 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase T2SE PF00437.15 OAJ12930.1 - 0.1 11.4 0.0 0.27 10.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 OAJ12930.1 - 0.15 11.2 0.0 0.92 8.7 0.0 2.2 2 1 1 3 3 3 0 PhoH-like protein DinB_2 PF12867.2 OAJ12931.1 - 0.04 14.2 1.7 2.7 8.3 0.2 2.5 2 0 0 2 2 2 0 DinB superfamily FAM60A PF15396.1 OAJ12931.1 - 0.78 9.4 14.9 0.032 13.9 3.8 2.1 2 0 0 2 2 2 0 Protein Family FAM60A DNA_pol_viral_N PF00242.12 OAJ12931.1 - 2.7 6.9 17.2 0.099 11.6 5.8 2.0 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Cwf_Cwc_15 PF04889.7 OAJ12931.1 - 5 6.7 23.6 0.5 10.0 9.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MAPEG PF01124.13 OAJ12932.1 - 1.9e-24 85.7 1.7 2.3e-24 85.4 1.2 1.1 1 0 0 1 1 1 1 MAPEG family LAG1-DNAbind PF09271.6 OAJ12934.1 - 5.8e-23 81.9 0.0 1.2e-18 67.9 0.0 2.5 2 0 0 2 2 2 2 LAG1, DNA binding BTD PF09270.5 OAJ12934.1 - 3e-17 62.8 0.0 6.6e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain TPR_12 PF13424.1 OAJ12936.1 - 4.2e-14 52.2 28.4 4.9e-06 26.3 4.4 5.8 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ12936.1 - 8.7e-07 28.6 24.2 0.27 11.2 1.5 7.8 8 1 1 9 9 9 4 Tetratricopeptide repeat DUF3856 PF12968.2 OAJ12936.1 - 0.0011 18.7 7.3 0.64 9.8 0.1 3.8 1 1 3 4 4 4 2 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.4 OAJ12936.1 - 0.0013 17.9 7.6 0.58 9.4 0.0 4.3 5 0 0 5 5 5 2 SHNi-TPR TPR_1 PF00515.23 OAJ12936.1 - 0.0014 18.1 13.9 6 6.6 0.5 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc5 PF12862.2 OAJ12936.1 - 0.0071 16.1 15.9 5.1 7.0 0.1 6.4 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 5 TPR_2 PF07719.12 OAJ12936.1 - 0.073 13.0 27.2 12 6.1 0.7 8.6 8 2 1 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ12936.1 - 0.19 12.4 17.9 10 7.0 0.6 6.6 7 1 1 8 8 8 0 Tetratricopeptide repeat PTPlike_phytase PF14566.1 OAJ12950.1 - 8.8e-109 360.1 0.0 3.5e-40 137.4 0.0 3.6 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.15 OAJ12950.1 - 0.0011 18.5 0.0 2.1 7.9 0.0 3.2 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain TFIIE-A_C-term PF11521.3 OAJ12950.1 - 0.0014 18.4 0.0 1.4 8.9 0.0 3.6 3 0 0 3 3 3 1 C-terminal general transcription factor TFIIE alpha Y_phosphatase PF00102.22 OAJ12950.1 - 0.045 13.0 0.2 31 3.8 0.0 3.2 3 0 0 3 3 3 0 Protein-tyrosine phosphatase MutS_V PF00488.16 OAJ12952.1 - 1.6e-50 171.7 0.0 3e-50 170.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAJ12952.1 - 2.6e-26 92.6 0.5 2.6e-26 92.6 0.4 1.8 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 OAJ12952.1 - 6.3e-06 26.2 1.4 0.08 13.0 0.7 3.7 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 OAJ12952.1 - 3.3e-05 23.9 0.0 8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV SMC_N PF02463.14 OAJ12952.1 - 0.01 15.0 0.1 1.5 7.9 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 OAJ12952.1 - 0.072 13.2 0.0 0.27 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.4 OAJ12952.1 - 0.26 10.1 3.2 0.45 9.3 0.1 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 DUF3433 PF11915.3 OAJ12966.1 - 0.1 12.7 0.6 0.27 11.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) F-box-like PF12937.2 OAJ12967.1 - 0.033 13.9 0.4 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 F-box-like LEAP-2 PF07359.6 OAJ12968.1 - 0.0067 16.0 19.2 0.22 11.1 1.2 3.5 2 1 1 3 3 3 3 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) UPF0506 PF11703.3 OAJ12968.1 - 0.2 11.6 40.4 0.24 11.3 2.1 4.4 3 1 1 4 4 4 0 UPF0506 EB PF01683.13 OAJ12968.1 - 5.1 7.2 45.4 1.8 8.6 3.4 4.7 2 2 2 4 4 4 0 EB module HIG_1_N PF04588.8 OAJ12969.1 - 2.8e-05 23.7 1.5 7e-05 22.4 1.1 1.7 1 0 0 1 1 1 1 Hypoxia induced protein conserved region ENOD93 PF03386.9 OAJ12969.1 - 0.005 16.5 0.3 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 Early nodulin 93 ENOD93 protein Aldo_ket_red PF00248.16 OAJ12970.1 - 1.3e-29 102.8 0.0 4.2e-28 97.9 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family DUF1640 PF07798.6 OAJ12971.1 - 5.8e-13 49.2 0.3 8.5e-13 48.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) SF-assemblin PF06705.6 OAJ12971.1 - 0.0035 16.5 2.0 0.0055 15.8 1.4 1.3 1 0 0 1 1 1 1 SF-assemblin/beta giardin OmpH PF03938.9 OAJ12971.1 - 0.0078 16.1 1.2 0.0078 16.1 0.8 2.1 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) F-box PF00646.28 OAJ12972.1 - 0.00028 20.4 0.0 0.00056 19.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ12972.1 - 0.00042 19.9 0.1 0.00089 18.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 OAJ12972.1 - 0.0049 16.5 0.0 0.0093 15.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain P53_TAD PF08563.6 OAJ12972.1 - 2 7.5 4.7 10 5.3 0.8 2.5 2 0 0 2 2 2 0 P53 transactivation motif F-box PF00646.28 OAJ12973.1 - 2.8e-06 26.8 0.0 7.3e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 F-box domain DUF4530 PF15039.1 OAJ12973.1 - 0.035 13.9 0.1 0.16 11.8 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4530) F-box-like PF12937.2 OAJ12973.1 - 0.041 13.6 0.0 0.099 12.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box-like_2 PF13013.1 OAJ12973.1 - 0.045 13.4 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain Dec-1 PF04624.9 OAJ12974.1 - 0.08 12.5 1.2 0.08 12.5 0.8 2.3 2 0 0 2 2 2 0 Dec-1 repeat zf-C3HC4 PF00097.20 OAJ12987.1 - 5.4e-08 32.3 12.4 7e-08 31.9 6.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ12987.1 - 1.2e-06 28.2 13.1 1.3e-05 24.9 7.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 OAJ12987.1 - 1.8e-06 27.7 9.1 1.8e-06 27.7 6.3 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 OAJ12987.1 - 4e-06 26.4 3.1 4e-06 26.4 2.1 2.1 3 0 0 3 3 2 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 OAJ12987.1 - 7.5e-06 25.8 13.6 1.4e-05 25.0 7.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ12987.1 - 1.6e-05 24.5 13.9 2.2e-05 24.1 6.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 OAJ12987.1 - 4.2e-05 23.3 4.9 0.00011 21.9 2.2 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 OAJ12987.1 - 5e-05 22.8 12.1 0.0003 20.3 6.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 OAJ12987.1 - 8.9e-05 21.8 1.0 0.00034 20.0 0.0 2.3 2 0 0 2 2 2 1 SAP domain zf-RING_UBOX PF13445.1 OAJ12987.1 - 0.00049 19.7 4.0 0.00049 19.7 2.8 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 OAJ12987.1 - 0.0033 16.9 4.8 0.0033 16.9 3.3 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Serglycin PF04360.7 OAJ12987.1 - 0.0049 16.6 0.5 0.009 15.7 0.3 1.4 1 0 0 1 1 1 1 Serglycin zf-rbx1 PF12678.2 OAJ12987.1 - 0.0066 16.5 7.3 0.047 13.8 2.9 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger Phage_Cox PF10743.4 OAJ12987.1 - 0.059 13.3 0.1 0.8 9.7 0.1 2.3 2 0 0 2 2 2 0 Regulatory phage protein cox DUF3505 PF12013.3 OAJ12987.1 - 0.077 13.2 2.5 2.6 8.3 0.0 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3505) FYVE PF01363.16 OAJ12987.1 - 0.72 9.7 10.4 6 6.8 0.1 2.6 2 0 0 2 2 2 0 FYVE zinc finger zf-MIZ PF02891.15 OAJ12987.1 - 1 8.9 11.7 3.5 7.2 5.8 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger NOB1_Zn_bind PF08772.6 OAJ12987.1 - 1.1 9.0 12.7 2.8 7.8 0.0 3.4 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf-RING_4 PF14570.1 OAJ12987.1 - 1.3 8.6 11.3 5 6.7 6.4 2.6 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DZR PF12773.2 OAJ12987.1 - 1.7 8.5 7.1 1.3 8.8 2.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon Kp4 PF09044.5 OAJ12988.1 - 0.015 15.1 0.2 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 Kp4 zf-RING_2 PF13639.1 OAJ12989.1 - 1e-10 41.2 7.9 1.5e-10 40.6 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAJ12989.1 - 8.4e-10 38.2 5.7 1.3e-09 37.6 4.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAJ12989.1 - 7.8e-09 35.4 7.1 1.2e-08 34.8 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ12989.1 - 9.4e-09 34.8 4.9 1.5e-08 34.1 3.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ12989.1 - 1.5e-07 30.9 6.1 2.4e-07 30.3 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAJ12989.1 - 7e-07 28.8 1.2 1.7e-06 27.6 0.2 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 OAJ12989.1 - 3.1e-06 27.1 3.9 5e-06 26.5 2.7 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 OAJ12989.1 - 0.00017 21.3 2.5 0.00017 21.3 1.8 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 OAJ12989.1 - 0.0028 17.2 6.6 0.0045 16.5 4.6 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 OAJ12989.1 - 0.0055 16.4 2.5 0.0095 15.7 1.7 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 OAJ12989.1 - 0.012 15.3 2.3 0.021 14.6 1.6 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.6 OAJ12989.1 - 0.016 14.9 0.3 0.024 14.3 0.2 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Baculo_RING PF05883.6 OAJ12989.1 - 0.14 11.9 0.6 0.21 11.3 0.4 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain DUF4637 PF15470.1 OAJ12989.1 - 0.14 11.7 7.0 0.32 10.6 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Rtf2 PF04641.7 OAJ12989.1 - 0.2 10.8 5.6 0.14 11.3 0.2 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger TerY-C PF15616.1 OAJ12989.1 - 0.27 11.1 2.9 0.54 10.1 2.0 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain Prok-RING_4 PF14447.1 OAJ12989.1 - 0.52 9.8 5.6 1.3 8.5 3.9 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 IBR PF01485.16 OAJ12989.1 - 0.91 9.4 7.9 1.2 9.0 4.8 1.8 1 1 0 1 1 1 0 IBR domain Btz PF09405.5 OAJ12990.1 - 1e-06 28.7 0.2 1e-06 28.7 0.1 4.6 4 1 1 5 5 5 2 CASC3/Barentsz eIF4AIII binding Daxx PF03344.10 OAJ12990.1 - 0.038 12.4 29.3 0.092 11.2 20.3 1.6 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 OAJ12990.1 - 0.38 9.9 23.4 0.66 9.2 16.2 1.3 1 0 0 1 1 1 0 SDA1 NST1 PF13945.1 OAJ12990.1 - 0.56 10.2 4.4 2.5 8.1 3.1 2.1 1 0 0 1 1 1 0 Salt tolerance down-regulator GOLD_2 PF13897.1 OAJ12990.1 - 2.9 8.1 3.5 7.8 6.7 2.4 1.7 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking MobB PF03205.9 OAJ12992.1 - 0.039 13.6 0.2 0.082 12.6 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Peptidase_S8 PF00082.17 OAJ13006.1 - 9.2e-56 189.0 3.9 1.3e-55 188.5 2.7 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 OAJ13006.1 - 1e-27 95.7 0.2 2e-27 94.7 0.1 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Fungal_trans PF04082.13 OAJ13008.1 - 1.1e-10 40.8 0.0 1.8e-09 36.8 0.0 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 OAJ13008.1 - 7.2e-05 22.9 10.3 0.014 15.7 0.8 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type Serglycin PF04360.7 OAJ13008.1 - 0.0016 18.1 0.8 0.0016 18.1 0.6 3.8 4 0 0 4 4 4 1 Serglycin zf-C2H2_4 PF13894.1 OAJ13008.1 - 0.0025 18.0 6.0 0.37 11.2 1.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 OAJ13008.1 - 0.18 11.7 7.9 0.68 9.9 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger F-box-like PF12937.2 OAJ13009.1 - 6.8e-12 44.9 0.1 6.8e-12 44.9 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ13009.1 - 1.4e-07 30.9 1.4 3.1e-07 29.8 0.1 2.1 2 0 0 2 2 2 1 F-box domain PQQ PF01011.16 OAJ13009.1 - 0.0071 15.8 0.1 0.23 11.0 0.0 2.5 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.1 OAJ13009.1 - 0.043 13.2 0.0 0.78 9.1 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain Usp PF00582.21 OAJ13010.1 - 0.00075 19.7 7.3 0.021 15.0 0.0 3.8 4 0 0 4 4 4 2 Universal stress protein family UPF0081 PF03652.10 OAJ13010.1 - 0.023 14.8 0.6 0.17 12.0 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0081) eIF-3c_N PF05470.7 OAJ13022.1 - 1.2e-182 608.1 4.1 1.2e-182 608.1 2.9 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 OAJ13022.1 - 5.3e-08 33.1 0.0 1.9e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 PCI domain DUF3818 PF12825.2 OAJ13022.1 - 0.12 11.0 0.5 0.26 9.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) DUF3439 PF11921.3 OAJ13022.1 - 1.8 8.3 6.5 0.11 12.2 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Acyl-CoA_dh_1 PF00441.19 OAJ13023.1 - 8.5e-37 126.5 0.1 1.2e-36 126.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ13023.1 - 1.1e-16 60.0 0.1 2e-16 59.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 OAJ13023.1 - 1e-14 55.0 0.2 2.7e-14 53.7 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAJ13023.1 - 3.3e-10 40.3 0.1 5.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RAMP4 PF06624.7 OAJ13024.1 - 0.00011 21.6 4.7 0.00035 20.0 3.3 1.8 1 1 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF4366 PF14283.1 OAJ13024.1 - 0.031 13.7 0.0 0.036 13.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) UQ_con PF00179.21 OAJ13025.1 - 1.9e-44 150.5 0.0 2.2e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Abhydrolase_6 PF12697.2 OAJ13026.1 - 5.7e-27 95.0 0.0 7.2e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ13026.1 - 2.7e-13 49.8 0.0 3.9e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ13026.1 - 2.7e-10 40.1 0.0 8e-10 38.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAJ13026.1 - 0.052 13.4 0.0 0.26 11.1 0.0 2.2 2 1 0 2 2 2 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 OAJ13026.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 OAJ13026.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_4 PF08386.5 OAJ13026.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Orn_Arg_deC_N PF02784.11 OAJ13027.1 - 1.6e-35 122.4 0.0 2.3e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 OAJ13027.1 - 5e-17 61.6 0.0 8.4e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain HD PF01966.17 OAJ13028.1 - 0.055 13.4 0.8 0.25 11.3 0.5 2.1 1 1 0 1 1 1 0 HD domain Peptidase_M48 PF01435.13 OAJ13029.1 - 1.3e-37 129.6 0.0 3.5e-36 124.8 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 OAJ13029.1 - 0.0079 15.1 0.1 0.0079 15.1 0.0 2.0 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF1168 PF06658.7 OAJ13030.1 - 4.3e-39 133.2 12.8 8e-39 132.3 8.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF3043 PF11241.3 OAJ13030.1 - 0.51 9.9 4.9 0.68 9.4 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DDHD PF02862.12 OAJ13030.1 - 3.2 7.4 6.4 4.8 6.9 4.5 1.2 1 0 0 1 1 1 0 DDHD domain Sec62 PF03839.11 OAJ13030.1 - 4.9 6.5 6.3 6.8 6.0 4.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Phage_integrase PF00589.17 OAJ13043.1 - 5.2e-05 22.9 0.0 6.6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family Vanabin-2 PF11437.3 OAJ13044.1 - 0.059 13.3 9.2 0.078 12.9 6.4 1.2 1 0 0 1 1 1 0 Vanadium-binding protein 2 WD40 PF00400.27 OAJ13045.1 - 1.5e-55 183.1 26.3 3.3e-10 39.4 0.0 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 OAJ13045.1 - 2.5e-14 53.4 1.1 8.4e-08 32.1 0.1 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 OAJ13045.1 - 0.019 13.8 0.0 0.039 12.7 0.0 1.5 1 1 0 1 1 1 0 Coatomer WD associated region Cytochrom_D1 PF02239.11 OAJ13045.1 - 0.067 11.4 0.0 0.14 10.4 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF4340 PF14238.1 OAJ13045.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4340) STAG PF08514.6 OAJ13046.1 - 8.1e-31 106.1 1.0 3e-30 104.3 0.7 2.0 1 0 0 1 1 1 1 STAG domain Peptidase_C48 PF02902.14 OAJ13047.1 - 3.7e-16 59.3 0.0 9.4e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.4 OAJ13047.1 - 8.4e-09 35.4 1.5 1.6e-07 31.4 0.4 3.0 2 1 0 2 2 2 1 MULE transposase domain SWIM PF04434.12 OAJ13047.1 - 0.013 15.0 0.6 0.027 13.9 0.4 1.5 1 0 0 1 1 1 0 SWIM zinc finger PALP PF00291.20 OAJ13059.1 - 1.8e-59 201.4 0.4 7.3e-37 127.2 0.1 2.0 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme Mit_ribos_Mrp51 PF11709.3 OAJ13061.1 - 0.00093 18.5 0.2 1.5 8.0 0.0 3.1 2 1 0 2 2 2 2 Mitochondrial ribosomal protein subunit zf-Mss51 PF13824.1 OAJ13062.1 - 5e-21 74.3 2.1 1.1e-20 73.2 1.5 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Calreticulin PF00262.13 OAJ13063.1 - 5.4e-156 518.8 12.4 6.9e-156 518.4 8.6 1.1 1 0 0 1 1 1 1 Calreticulin family MtrD PF04207.7 OAJ13063.1 - 0.0027 17.1 2.6 0.0041 16.5 1.8 1.2 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit D DUF883 PF05957.8 OAJ13063.1 - 0.0063 16.8 2.9 0.0063 16.8 2.0 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) Peptidase_S3 PF00944.14 OAJ13077.1 - 0.035 13.5 0.3 0.047 13.1 0.2 1.2 1 0 0 1 1 1 0 Alphavirus core protein Coq4 PF05019.8 OAJ13078.1 - 1.3e-78 262.9 0.0 1.7e-78 262.5 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 MMS19_N PF14500.1 OAJ13079.1 - 1e-60 205.2 0.8 2.1e-59 200.9 0.5 2.2 1 1 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 OAJ13079.1 - 4e-15 55.4 0.0 9.7e-14 50.9 0.0 2.8 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal RNase_T PF00929.19 OAJ13080.1 - 1.8e-23 83.5 0.0 2.6e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 OAJ13080.1 - 0.0016 17.9 0.0 0.005 16.3 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease DUF1658 PF07871.6 OAJ13080.1 - 0.012 15.1 1.1 0.012 15.1 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) Sporozoite_P67 PF05642.6 OAJ13080.1 - 0.54 8.0 4.5 1 7.1 2.7 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 OAJ13080.1 - 2 8.7 6.9 0.91 9.8 2.9 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 OAJ13080.1 - 2.8 5.8 5.5 3.6 5.4 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_20 PF00728.17 OAJ13081.1 - 2.1e-24 86.3 0.0 3.5e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Ribosomal_60s PF00428.14 OAJ13081.1 - 2.6 8.4 9.4 2e+02 2.4 7.9 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Nop14 PF04147.7 OAJ13081.1 - 5.4 4.8 6.1 9.6 3.9 4.2 1.3 1 0 0 1 1 1 0 Nop14-like family Abhydrolase_3 PF07859.8 OAJ13082.1 - 5.2e-49 166.6 0.1 8.2e-49 166.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAJ13082.1 - 9.9e-13 47.4 0.0 2.4e-12 46.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 OAJ13082.1 - 0.00027 20.6 0.0 0.00055 19.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_10 PF12846.2 OAJ13083.1 - 0.6 9.4 3.1 1.1 8.6 2.1 1.3 1 0 0 1 1 1 0 AAA-like domain La PF05383.12 OAJ13094.1 - 2.2e-16 59.3 0.0 3.3e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 La domain CoA_binding_2 PF13380.1 OAJ13095.1 - 7.3e-32 109.9 0.1 8.7e-32 109.7 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 OAJ13095.1 - 5.6e-05 23.5 0.0 8.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain NAD_kinase PF01513.16 OAJ13096.1 - 6.9e-66 221.9 0.0 3.4e-65 219.6 0.0 1.9 1 1 0 1 1 1 1 ATP-NAD kinase TFIIA PF03153.8 OAJ13096.1 - 0.14 12.0 17.5 0.33 10.8 12.2 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 OAJ13096.1 - 0.57 8.0 22.7 0.077 10.9 12.6 1.8 2 0 0 2 2 2 0 Nop14-like family Nucleoplasmin PF03066.10 OAJ13096.1 - 0.77 9.2 22.5 0.082 12.4 10.8 2.4 2 0 0 2 2 2 0 Nucleoplasmin DUF2457 PF10446.4 OAJ13096.1 - 8.1 5.0 29.8 1.5 7.4 17.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) tRNA_anti-codon PF01336.20 OAJ13097.1 - 0.0042 16.9 1.2 0.008 16.0 0.8 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF966 PF06136.8 OAJ13097.1 - 0.42 9.9 13.6 0.04 13.3 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) PAP2 PF01569.16 OAJ13098.1 - 1.8e-25 89.0 6.0 1.8e-25 89.0 4.1 1.6 2 0 0 2 2 2 1 PAP2 superfamily DNA_mis_repair PF01119.14 OAJ13110.1 - 2.2e-31 107.7 0.0 3.7e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 OAJ13110.1 - 3.5e-12 46.1 0.0 1.1e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 OAJ13110.1 - 1.2e-10 41.0 0.0 5.9e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nop14 PF04147.7 OAJ13110.1 - 2e-05 22.7 21.8 2.9e-05 22.2 15.1 1.2 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 OAJ13110.1 - 0.0023 16.4 25.9 0.0044 15.5 17.9 1.4 1 0 0 1 1 1 1 Daxx Family YL1 PF05764.8 OAJ13110.1 - 0.0032 17.0 22.2 0.0059 16.2 15.4 1.3 1 0 0 1 1 1 1 YL1 nuclear protein SDA1 PF05285.7 OAJ13110.1 - 0.0061 15.8 22.5 0.011 15.0 15.6 1.3 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.9 OAJ13110.1 - 0.0084 14.2 18.3 0.014 13.4 12.7 1.2 1 0 0 1 1 1 1 CDC45-like protein DUF1510 PF07423.6 OAJ13110.1 - 0.17 11.2 19.4 0.3 10.4 13.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PPP4R2 PF09184.6 OAJ13110.1 - 0.28 10.6 21.6 0.55 9.7 15.0 1.5 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.8 OAJ13110.1 - 0.42 10.4 27.6 0.022 14.7 15.4 1.5 2 0 0 2 2 1 0 Transcription factor IIA, alpha/beta subunit Spore_coat_CotO PF14153.1 OAJ13110.1 - 0.47 9.8 10.0 0.8 9.1 6.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO TFIIF_alpha PF05793.7 OAJ13110.1 - 0.77 8.0 27.3 1.4 7.1 18.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cwf_Cwc_15 PF04889.7 OAJ13110.1 - 1.1 8.9 19.2 1.9 8.1 13.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ycf1 PF05758.7 OAJ13110.1 - 1.4 6.5 5.2 1.8 6.1 3.6 1.1 1 0 0 1 1 1 0 Ycf1 VID27 PF08553.5 OAJ13110.1 - 2.1 6.4 19.4 3.2 5.8 13.4 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Lin-8 PF03353.10 OAJ13110.1 - 3.5 6.8 11.2 7.9 5.6 7.8 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BUD22 PF09073.5 OAJ13110.1 - 3.5 6.5 26.4 6 5.8 18.3 1.3 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.7 OAJ13110.1 - 5.8 5.1 30.8 8.6 4.5 21.3 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC27 PF09507.5 OAJ13110.1 - 7 5.7 22.7 11 5.0 15.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DCP1 PF06058.8 OAJ13111.1 - 4.9e-16 58.8 0.0 5.1e-08 33.0 0.0 2.7 2 1 0 2 2 2 2 Dcp1-like decapping family Zn_clus PF00172.13 OAJ13112.1 - 1.8e-05 24.5 2.8 4.6e-05 23.2 2.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltrn_RNA_3 PF02598.12 OAJ13113.1 - 3e-74 250.0 0.0 5.4e-74 249.1 0.0 1.4 1 1 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 OAJ13113.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 SpoU rRNA Methylase family NGP1NT PF08153.7 OAJ13114.1 - 1e-41 141.9 0.0 2.4e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 OAJ13114.1 - 2.4e-17 62.9 0.0 4.3e-14 52.4 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase Arf PF00025.16 OAJ13114.1 - 0.00028 20.1 0.1 0.041 13.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.13 OAJ13114.1 - 0.00089 18.5 0.1 0.002 17.4 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 OAJ13114.1 - 0.0021 17.2 0.0 0.0047 16.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 OAJ13114.1 - 0.01 15.2 0.2 0.41 10.0 0.0 3.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 OAJ13114.1 - 0.28 11.0 0.0 0.28 11.0 0.0 4.5 5 1 1 6 6 6 0 Dynamin family MSC PF09402.5 OAJ13115.1 - 2.6e-36 124.9 0.0 2.8e-19 69.0 0.0 3.9 2 2 0 2 2 2 2 Man1-Src1p-C-terminal domain DinB_2 PF12867.2 OAJ13129.1 - 0.0002 21.7 0.2 0.00041 20.6 0.1 1.4 1 1 0 1 1 1 1 DinB superfamily MDMPI_N PF11716.3 OAJ13129.1 - 0.0083 16.5 0.2 0.014 15.8 0.1 1.3 1 0 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain DASH_Dad3 PF08656.5 OAJ13130.1 - 2.7e-19 68.6 0.4 3.4e-19 68.3 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Fork_head PF00250.13 OAJ13131.1 - 3.3e-21 75.1 0.1 1.6e-19 69.7 0.0 2.5 1 1 0 1 1 1 1 Fork head domain BAF1_ABF1 PF04684.8 OAJ13131.1 - 0.024 13.5 31.8 0.036 12.9 22.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 OAJ13131.1 - 0.08 11.9 0.4 0.13 11.2 0.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 OAJ13131.1 - 1.9 8.3 4.3 2.6 7.8 0.8 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.9 OAJ13131.1 - 2.1 7.9 8.8 4.9 6.7 6.1 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.2 OAJ13131.1 - 8.5 3.9 6.2 13 3.2 4.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dynein_heavy PF03028.10 OAJ13132.1 - 2.5e-168 561.3 0.0 5.1e-168 560.3 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 OAJ13132.1 - 1.4e-46 158.8 4.8 2.7e-46 157.9 3.3 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 OAJ13132.1 - 3.1e-46 157.0 0.5 3e-45 153.8 0.0 2.5 2 1 0 2 2 2 1 ATP-binding dynein motor region D5 Reo_sigmaC PF04582.7 OAJ13132.1 - 4.7 6.2 12.1 0.67 9.0 0.3 3.5 4 0 0 4 4 4 0 Reovirus sigma C capsid protein IFT46_B_C PF12317.3 OAJ13132.1 - 7.5 5.8 8.0 1.2 8.4 0.1 3.0 3 0 0 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal Sugar_tr PF00083.19 OAJ13133.1 - 2.1e-70 237.5 10.8 2.2e-38 131.9 0.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ13133.1 - 8.1e-19 67.5 38.7 9.6e-19 67.2 22.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Helicase_C PF00271.26 OAJ13147.1 - 2.3e-12 46.5 0.1 5.6e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ13147.1 - 6.5e-09 35.5 0.0 1.6e-08 34.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase UbiA PF01040.13 OAJ13149.1 - 2.5e-31 108.8 22.4 7.1e-31 107.3 15.5 1.6 1 1 0 1 1 1 1 UbiA prenyltransferase family Glyco_transf_20 PF00982.16 OAJ13150.1 - 8e-142 473.0 0.0 1.7e-130 435.7 0.0 2.5 2 1 0 3 3 3 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 OAJ13150.1 - 1.2e-77 260.0 0.0 1.8e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 OAJ13150.1 - 1.9e-05 24.3 0.0 0.0078 15.8 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase rve_3 PF13683.1 OAJ13150.1 - 0.0018 17.7 0.0 0.0054 16.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain S6PP PF05116.8 OAJ13150.1 - 0.0024 17.2 0.1 0.012 14.8 0.0 1.9 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Pox_A_type_inc PF04508.7 OAJ13150.1 - 0.68 9.8 2.1 4 7.4 0.6 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat zf-CCHC PF00098.18 OAJ13151.1 - 0.054 13.4 0.6 0.15 12.0 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle Arf PF00025.16 OAJ13167.1 - 4e-36 123.8 0.0 1.4e-24 86.3 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 OAJ13167.1 - 3.5e-13 49.2 0.0 1.6e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 OAJ13167.1 - 2.9e-08 33.1 0.0 5.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 OAJ13167.1 - 2.6e-07 31.1 0.0 8e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 OAJ13167.1 - 6.5e-06 25.4 0.0 9.2e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 OAJ13167.1 - 1.5e-05 23.9 0.0 2.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 OAJ13167.1 - 0.00047 20.1 0.0 0.00072 19.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 OAJ13167.1 - 0.044 13.5 0.1 0.089 12.6 0.1 1.5 2 0 0 2 2 2 0 Dynamin family GTP_EFTU PF00009.22 OAJ13167.1 - 0.11 11.9 0.0 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DPBB_1 PF03330.13 OAJ13168.1 - 0.00029 20.7 0.1 0.0016 18.4 0.1 2.1 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ13168.1 - 0.0095 15.6 0.1 0.013 15.1 0.1 1.2 1 0 0 1 1 1 1 Barwin family eIF3_subunit PF08597.5 OAJ13170.1 - 0.24 10.9 12.8 0.37 10.3 8.9 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SBP_bac_7 PF03480.8 OAJ13170.1 - 1.1 8.2 6.7 1.4 7.9 4.0 1.6 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Tom37_C PF11801.3 OAJ13170.1 - 2 8.2 7.4 3.2 7.5 5.1 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Spore_coat_CotO PF14153.1 OAJ13170.1 - 3.2 7.1 9.5 4.8 6.5 6.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO FUSC PF04632.7 OAJ13170.1 - 9.4 4.5 6.9 13 4.0 4.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family IBN_N PF03810.14 OAJ13173.1 - 1.8e-07 31.0 0.0 2.3e-05 24.2 0.0 3.4 2 1 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 OAJ13173.1 - 0.0076 16.1 0.1 0.19 11.6 0.0 3.2 2 1 0 2 2 2 1 Exportin 1-like protein Med16 PF11635.3 OAJ13189.1 - 0.002 16.2 0.0 0.013 13.5 0.0 1.9 2 0 0 2 2 2 1 Mediator complex subunit 16 Polysacc_deac_1 PF01522.16 OAJ13190.1 - 1.2e-27 95.9 0.0 2e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Mito_carr PF00153.22 OAJ13192.1 - 2.6e-28 97.5 2.2 1.6e-14 53.3 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein B12D PF06522.6 OAJ13193.1 - 2.5e-14 52.7 0.0 3e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit GTP_EFTU PF00009.22 OAJ13194.1 - 6.6e-47 159.3 0.1 1.4e-46 158.3 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 OAJ13194.1 - 3.1e-22 78.6 0.1 1.2e-21 76.7 0.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 OAJ13194.1 - 4.3e-08 33.1 0.2 1.6e-07 31.3 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAJ13194.1 - 0.00011 22.1 0.0 0.0003 20.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Med15 PF09606.5 OAJ13194.1 - 0.055 11.6 54.6 0.079 11.1 37.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MSP1_C PF07462.6 OAJ13194.1 - 0.68 8.2 9.7 1.1 7.5 6.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus TFIIA PF03153.8 OAJ13194.1 - 2.8 7.7 33.2 4.7 7.0 23.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HTH_Tnp_4 PF13613.1 OAJ13207.1 - 0.025 14.1 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 OAJ13207.1 - 0.049 13.2 0.1 0.049 13.2 0.1 2.3 2 0 0 2 2 2 0 Homeodomain-like domain DUF3853 PF12964.2 OAJ13207.1 - 0.099 12.4 0.1 0.24 11.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3853) HTH_28 PF13518.1 OAJ13207.1 - 0.15 12.0 5.5 2.4 8.2 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Herpes_capsid PF06112.6 OAJ13207.1 - 0.19 11.7 5.3 0.24 11.4 3.6 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein TFIIE_alpha PF02002.12 OAJ13208.1 - 5.8e-09 35.4 0.0 1.1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit zf-C2H2_6 PF13912.1 OAJ13208.1 - 0.12 12.2 0.1 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C3HC4_3 PF13920.1 OAJ13209.1 - 0.058 13.0 0.2 0.085 12.5 0.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.6 OAJ13226.1 - 0.00086 18.9 1.0 0.038 13.6 0.0 2.6 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Acetyltransf_10 PF13673.1 OAJ13226.1 - 0.018 15.1 0.0 0.075 13.1 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_85 PF03644.8 OAJ13227.1 - 6e-10 38.7 0.2 9.1e-10 38.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 RRM_6 PF14259.1 OAJ13229.1 - 0.00092 19.1 0.0 0.1 12.5 0.0 3.3 3 1 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) BCDHK_Adom3 PF10436.4 OAJ13230.1 - 4.5e-05 23.0 0.1 7.4e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Fungal_trans PF04082.13 OAJ13245.1 - 6.2e-16 58.0 4.2 1e-15 57.3 2.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ13245.1 - 0.00011 21.9 7.7 0.00021 21.1 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Daxx PF03344.10 OAJ13245.1 - 0.00085 17.9 6.2 0.00085 17.9 4.3 1.7 2 0 0 2 2 2 1 Daxx Family CENP-B_dimeris PF09026.5 OAJ13245.1 - 0.44 10.8 19.4 1.2 9.3 11.4 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Mito_carr PF00153.22 OAJ13246.1 - 2.5e-38 129.6 2.3 3.6e-14 52.2 0.1 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein Borrelia_P83 PF05262.6 OAJ13248.1 - 0.91 7.7 11.2 1.3 7.2 7.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein NARP1 PF12569.3 OAJ13248.1 - 1.2 7.8 12.9 1.8 7.2 8.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2413 PF10310.4 OAJ13248.1 - 2.1 7.0 12.4 3.3 6.4 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DDRGK PF09756.4 OAJ13248.1 - 5.1 6.4 13.9 7.9 5.8 9.6 1.2 1 0 0 1 1 1 0 DDRGK domain DUF4407 PF14362.1 OAJ13248.1 - 7.2 5.4 11.0 11 4.8 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.7 OAJ13248.1 - 7.8 6.3 10.1 14 5.4 7.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TPR_12 PF13424.1 OAJ13264.1 - 9.8e-39 131.1 56.3 7.3e-09 35.4 0.4 8.7 2 1 8 11 11 11 10 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ13264.1 - 2.4e-24 84.4 40.2 0.00052 19.8 0.2 12.5 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ13264.1 - 2.1e-08 33.3 6.5 7.5 6.5 0.0 9.4 10 1 0 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ13264.1 - 1.8e-06 27.4 23.8 0.31 10.7 0.6 7.5 3 1 6 9 9 9 7 TPR repeat SHNi-TPR PF10516.4 OAJ13264.1 - 3.1e-06 26.2 6.9 1.7 7.9 0.1 7.0 7 0 0 7 7 7 1 SHNi-TPR TPR_1 PF00515.23 OAJ13264.1 - 8.8e-06 25.1 11.7 0.79 9.4 0.0 9.0 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ13264.1 - 3.6e-05 23.3 26.8 0.73 9.9 0.1 10.6 12 0 0 12 12 11 1 Tetratricopeptide repeat Apc5 PF12862.2 OAJ13264.1 - 0.00043 20.0 9.7 27 4.7 0.0 7.7 4 2 2 6 6 6 0 Anaphase-promoting complex subunit 5 TPR_19 PF14559.1 OAJ13264.1 - 0.0033 17.7 6.6 2 8.8 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat DUF2186 PF09952.4 OAJ13264.1 - 0.0058 16.8 0.7 0.4 10.9 0.0 3.3 3 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2186) DUF3856 PF12968.2 OAJ13264.1 - 0.061 13.1 8.7 4.9 6.9 0.0 5.3 4 1 0 6 6 6 0 Domain of Unknown Function (DUF3856) TPR_7 PF13176.1 OAJ13264.1 - 2.7 8.0 18.2 0.7 9.8 0.0 7.4 10 0 0 10 10 8 0 Tetratricopeptide repeat PPR PF01535.15 OAJ13264.1 - 7.8 6.7 9.0 1.1e+02 3.0 0.0 6.2 6 0 0 6 6 6 0 PPR repeat TPR_4 PF07721.9 OAJ13264.1 - 8.8 7.0 16.0 20 5.9 0.4 6.5 7 0 0 7 7 5 0 Tetratricopeptide repeat ENTH PF01417.15 OAJ13265.1 - 2.8e-44 149.9 0.1 3.8e-44 149.5 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 OAJ13265.1 - 0.0018 17.0 0.1 0.0024 16.6 0.1 1.1 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 OAJ13265.1 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 VHS domain DUF3366 PF11846.3 OAJ13266.1 - 0.097 12.5 0.3 0.097 12.5 0.2 4.0 3 1 2 5 5 5 0 Domain of unknown function (DUF3366) DUF2721 PF11026.3 OAJ13266.1 - 0.1 12.2 0.2 0.1 12.2 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) PQ-loop PF04193.9 OAJ13267.1 - 6.4e-32 108.8 13.0 2.3e-18 65.5 1.3 2.8 3 0 0 3 3 3 2 PQ loop repeat PLDc_N PF13396.1 OAJ13267.1 - 0.0085 15.7 0.1 0.0085 15.7 0.1 2.4 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal DUF1301 PF06979.7 OAJ13267.1 - 0.16 12.1 0.5 0.45 10.6 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1301) DUF3366 PF11846.3 OAJ13268.1 - 0.041 13.7 3.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) Phage_integrase PF00589.17 OAJ13281.1 - 0.017 14.8 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family F-box-like PF12937.2 OAJ13282.1 - 0.00015 21.3 0.2 0.00032 20.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 OAJ13282.1 - 0.055 13.2 0.3 0.4 10.4 0.3 2.2 1 1 1 2 2 2 0 Leucine rich repeat RVT_1 PF00078.22 OAJ13284.1 - 1.9e-26 92.7 0.0 8.3e-26 90.6 0.0 2.0 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) WES_acyltransf PF03007.11 OAJ13285.1 - 9.2e-18 64.7 0.0 2e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF566 PF04484.7 OAJ13285.1 - 3.3 7.1 7.4 6.3 6.2 5.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) DSBA PF01323.15 OAJ13297.1 - 2.3e-24 86.0 0.0 3.1e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Formyl_trans_N PF00551.14 OAJ13298.1 - 2.4e-20 72.8 0.0 3.1e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 OAJ13298.1 - 1e-06 28.7 0.0 2.4e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Formyl transferase, C-terminal domain DKCLD PF08068.7 OAJ13299.1 - 1.8e-29 101.4 0.1 5.7e-29 99.8 0.1 1.8 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 OAJ13299.1 - 2.2e-24 86.3 0.2 3.6e-21 75.9 0.1 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 OAJ13299.1 - 2.2e-19 68.9 0.7 4.8e-19 67.8 0.5 1.6 1 0 0 1 1 1 1 PUA domain Ima1_N PF09779.4 OAJ13300.1 - 6.2e-20 72.0 0.3 6.2e-20 72.0 0.2 1.8 2 0 0 2 2 2 1 Ima1 N-terminal domain Sporozoite_P67 PF05642.6 OAJ13300.1 - 0.024 12.5 10.1 0.036 11.9 7.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.6 OAJ13300.1 - 0.52 8.2 9.6 0.85 7.5 6.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Methyltransf_26 PF13659.1 OAJ13301.1 - 1.8e-10 40.8 0.0 3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ13301.1 - 1.8e-06 27.4 0.0 0.00015 21.1 0.0 2.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 OAJ13301.1 - 0.03 14.6 0.0 0.068 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 OAJ13301.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 OAJ13301.1 - 0.13 12.7 0.0 0.3 11.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Abhydrolase_6 PF12697.2 OAJ13302.1 - 1.7e-17 64.0 0.9 1.2e-16 61.3 0.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ13302.1 - 2.6e-16 59.7 0.0 7.2e-16 58.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ13302.1 - 4.9e-11 42.3 0.0 9.1e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 OAJ13302.1 - 1.9e-06 27.6 1.1 0.00032 20.3 0.6 3.3 3 1 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 OAJ13302.1 - 4.9e-05 22.8 0.0 0.00072 19.0 0.0 2.6 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Phage_integrase PF00589.17 OAJ13303.1 - 0.00029 20.5 0.0 0.00039 20.1 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family 2_5_RNA_ligase2 PF13563.1 OAJ13320.1 - 1.3e-16 60.6 1.5 5.2e-09 36.0 0.1 2.2 2 0 0 2 2 2 2 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 OAJ13320.1 - 9.8e-05 22.2 0.2 0.21 11.5 0.0 3.0 3 0 0 3 3 3 2 LigT like Phosphoesterase CPDase PF07823.6 OAJ13320.1 - 0.0036 16.8 0.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 2 Cyclic phosphodiesterase-like protein TruB_N PF01509.13 OAJ13321.1 - 4.1e-37 127.6 0.0 5.9e-36 123.8 0.0 2.1 1 1 1 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) DUF4637 PF15470.1 OAJ13321.1 - 0.012 15.2 1.8 0.012 15.2 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) DKCLD PF08068.7 OAJ13321.1 - 0.089 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 DKCLD (NUC011) domain F-box-like PF12937.2 OAJ13322.1 - 0.0002 21.0 0.6 0.00064 19.3 0.4 1.9 1 0 0 1 1 1 1 F-box-like TatD_DNase PF01026.16 OAJ13323.1 - 2.4e-19 69.5 0.4 4.6e-19 68.6 0.3 1.5 1 0 0 1 1 1 1 TatD related DNase Nop14 PF04147.7 OAJ13327.1 - 2.3 6.0 6.8 2.8 5.7 4.7 1.1 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 OAJ13327.1 - 3.4 6.7 8.9 3.1 6.8 5.1 1.7 1 1 0 1 1 1 0 Myc amino-terminal region SH3_9 PF14604.1 OAJ13345.1 - 2.7e-15 55.6 0.0 5.7e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 OAJ13345.1 - 2.4e-14 53.4 0.0 4.9e-13 49.1 0.0 2.3 2 0 0 2 2 2 1 PH domain SH3_1 PF00018.23 OAJ13345.1 - 3e-12 45.7 0.4 6.9e-12 44.5 0.3 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ13345.1 - 1.9e-09 36.8 0.0 4.9e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 OAJ13345.1 - 2.6e-07 30.4 0.0 4.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 OAJ13345.1 - 0.00069 19.7 0.0 0.0021 18.2 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF3104 PF11302.3 OAJ13345.1 - 0.14 11.5 0.0 0.36 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Ste50p-SAM PF09235.5 OAJ13345.1 - 0.19 11.7 0.3 0.39 10.7 0.2 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif KGG PF10685.4 OAJ13346.1 - 7.3e-07 28.9 2.2 7.3e-07 28.9 1.6 4.1 3 1 0 3 3 3 2 Stress-induced bacterial acidophilic repeat motif RNA_pol_3_Rpc31 PF11705.3 OAJ13346.1 - 3.2 7.6 8.9 3.8 7.3 6.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Spore_coat_CotO PF14153.1 OAJ13347.1 - 0.0011 18.4 8.0 0.0014 18.0 5.5 1.3 1 0 0 1 1 1 1 Spore coat protein CotO SAPS PF04499.10 OAJ13347.1 - 0.0013 17.4 5.3 0.0018 16.9 3.7 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Sec62 PF03839.11 OAJ13347.1 - 0.058 12.7 2.6 0.087 12.2 1.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4407 PF14362.1 OAJ13347.1 - 0.061 12.2 12.8 0.097 11.6 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BUD22 PF09073.5 OAJ13347.1 - 0.13 11.3 24.4 0.21 10.6 16.9 1.3 1 0 0 1 1 1 0 BUD22 Ycf1 PF05758.7 OAJ13347.1 - 0.29 8.8 13.5 0.39 8.3 9.4 1.1 1 0 0 1 1 1 0 Ycf1 CobT PF06213.7 OAJ13347.1 - 0.59 9.2 24.6 0.85 8.6 17.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mem_trans PF03547.13 OAJ13347.1 - 1 7.5 3.5 1.6 6.9 2.4 1.4 1 0 0 1 1 1 0 Membrane transport protein Merozoite_SPAM PF07133.6 OAJ13347.1 - 1.3 8.9 30.1 2 8.3 20.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RR_TM4-6 PF06459.7 OAJ13347.1 - 1.7 8.4 17.1 3 7.6 11.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.7 OAJ13347.1 - 3.5 5.4 32.1 4.8 4.9 22.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 OAJ13347.1 - 4.6 6.5 27.8 7.3 5.8 19.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Thioredoxin PF00085.15 OAJ13348.1 - 5.7e-34 115.9 0.0 9e-22 76.7 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 OAJ13348.1 - 5.4e-12 45.8 0.0 0.0071 16.1 0.0 3.9 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 OAJ13348.1 - 9.4e-08 32.2 0.8 0.001 19.2 0.2 3.9 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_3 PF13192.1 OAJ13348.1 - 7.9e-06 25.5 0.0 0.0027 17.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_8 PF13905.1 OAJ13348.1 - 0.0012 18.8 0.1 0.01 15.9 0.1 2.5 2 1 1 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 OAJ13348.1 - 0.01 15.4 0.0 0.038 13.6 0.0 2.0 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 OAJ13348.1 - 0.036 13.6 0.1 0.34 10.4 0.0 2.4 2 0 0 2 2 2 0 Redoxin Thioredoxin_4 PF13462.1 OAJ13348.1 - 0.087 12.8 0.5 0.54 10.2 0.2 2.2 2 0 0 2 2 2 0 Thioredoxin CTD PF12815.2 OAJ13349.1 - 3.3e-10 40.4 57.3 4.3e-06 27.1 24.9 4.6 1 1 2 3 3 3 3 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.24 OAJ13349.1 - 4e-06 26.3 16.5 0.0042 16.7 0.1 4.6 6 0 0 6 6 6 3 KOW motif DUF3006 PF11213.3 OAJ13349.1 - 0.0088 15.7 0.1 0.045 13.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) YajC PF02699.10 OAJ13349.1 - 0.11 12.2 0.4 15 5.3 0.0 2.5 2 0 0 2 2 2 0 Preprotein translocase subunit GrpE PF01025.14 OAJ13368.1 - 1.3e-42 145.1 0.1 1.9e-42 144.6 0.1 1.2 1 0 0 1 1 1 1 GrpE Sel1 PF08238.7 OAJ13369.1 - 4.7e-16 58.8 19.6 3.5e-06 27.4 0.2 4.5 4 0 0 4 4 4 3 Sel1 repeat TPR_11 PF13414.1 OAJ13369.1 - 0.1 12.2 5.1 1.1 9.0 0.0 3.3 3 1 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 OAJ13369.1 - 4 7.5 5.8 6.2 6.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat RhoGEF PF00621.15 OAJ13370.1 - 1.7e-36 125.8 0.0 3.4e-36 124.7 0.0 1.5 1 1 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 OAJ13370.1 - 6.3e-18 64.4 9.3 1.2e-17 63.5 6.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 OAJ13370.1 - 2.7e-09 37.1 0.0 5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 PH domain Kdo PF06293.9 OAJ13371.1 - 4.3e-05 22.6 0.0 0.001 18.1 0.0 2.4 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 OAJ13371.1 - 0.00014 21.1 0.0 0.00022 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 OAJ13371.1 - 0.00059 19.6 0.0 0.0084 15.8 0.0 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 OAJ13371.1 - 0.032 13.3 0.0 4.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Ecdysteroid kinase RIO1 PF01163.17 OAJ13371.1 - 0.053 12.8 0.0 3.8 6.7 0.0 2.2 2 0 0 2 2 2 0 RIO1 family TPP1 PF10341.4 OAJ13372.1 - 2.5e-05 24.1 0.0 4.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD TB2_DP1_HVA22 PF03134.14 OAJ13373.1 - 8.1e-29 99.2 6.6 1.1e-28 98.7 4.6 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DNA_topoisoIV PF00521.15 OAJ13374.1 - 7.1e-127 423.7 0.1 2.4e-126 422.0 0.0 1.9 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 OAJ13374.1 - 6e-34 116.7 0.5 1.5e-33 115.4 0.3 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 OAJ13374.1 - 2.4e-14 53.1 0.0 2.9e-13 49.6 0.0 2.8 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 OAJ13374.1 - 1.5e-07 31.1 0.0 4.5e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC27 PF09507.5 OAJ13374.1 - 3.2 6.8 33.8 0.068 12.3 15.6 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Metallophos PF00149.23 OAJ13387.1 - 5.1e-43 146.8 0.9 6.3e-43 146.4 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HA2 PF04408.18 OAJ13389.1 - 2.1e-24 85.4 0.1 1.2e-23 83.0 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 OAJ13389.1 - 3.3e-24 84.9 0.0 8.9e-24 83.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 OAJ13389.1 - 2.8e-14 52.7 0.0 6.6e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ13389.1 - 1.7e-06 27.6 0.0 4.5e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ13389.1 - 0.00074 19.6 0.0 0.0025 17.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 OAJ13389.1 - 0.0048 15.8 0.0 0.0089 14.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 OAJ13389.1 - 0.01 15.2 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 OAJ13389.1 - 0.012 15.5 1.2 0.86 9.5 0.0 3.4 2 1 0 2 2 2 0 AAA domain PWI PF01480.12 OAJ13389.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 PWI domain ResIII PF04851.10 OAJ13389.1 - 0.028 14.2 0.0 7.4 6.3 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 OAJ13389.1 - 0.065 12.9 0.0 0.24 11.1 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 OAJ13389.1 - 0.14 12.4 1.0 0.45 10.8 0.1 2.3 1 1 1 2 2 2 0 ABC transporter UPF0079 PF02367.12 OAJ13389.1 - 0.15 11.7 0.0 0.42 10.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 OAJ13389.1 - 1.5 9.1 0.0 1.5 9.1 0.0 2.9 2 1 0 2 2 1 0 AAA domain CopD PF05425.8 OAJ13409.1 - 0.16 12.2 6.8 0.46 10.7 0.3 2.7 2 1 1 3 3 3 0 Copper resistance protein D PHD PF00628.24 OAJ13410.1 - 0.00013 21.6 8.1 0.00013 21.6 5.6 2.4 3 0 0 3 3 3 1 PHD-finger HALZ PF02183.13 OAJ13410.1 - 0.053 13.2 1.8 2.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper TSC22 PF01166.13 OAJ13410.1 - 0.19 11.7 1.5 3.1 7.8 0.0 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family zf-HC5HC2H_2 PF13832.1 OAJ13410.1 - 0.21 11.6 3.1 3.7 7.5 0.6 2.7 3 0 0 3 3 3 0 PHD-zinc-finger like domain rve PF00665.21 OAJ13413.1 - 3.1e-07 30.5 0.0 1.2e-06 28.5 0.0 2.1 2 1 0 2 2 2 1 Integrase core domain CPSase_L_D3 PF02787.14 OAJ13413.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain PQ-loop PF04193.9 OAJ13414.1 - 3.1e-35 119.5 12.2 9.4e-18 63.5 1.8 2.5 2 0 0 2 2 2 2 PQ loop repeat Frag1 PF10277.4 OAJ13414.1 - 0.00021 20.8 5.2 0.00038 20.0 3.6 1.4 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Mg_trans_NIPA PF05653.9 OAJ13414.1 - 0.0058 15.6 2.2 0.013 14.4 1.4 1.6 1 1 1 2 2 2 1 Magnesium transporter NIPA Form-deh_trans PF09163.6 OAJ13414.1 - 0.0085 15.5 0.1 0.023 14.1 0.1 1.7 1 0 0 1 1 1 1 Formate dehydrogenase N, transmembrane Arteri_Gl PF00951.13 OAJ13414.1 - 0.017 14.6 0.7 0.042 13.4 0.5 1.6 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein DUF2781 PF10914.3 OAJ13414.1 - 0.054 13.2 1.0 0.11 12.2 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) tRNA_int_endo PF01974.12 OAJ13416.1 - 1.6e-19 69.4 0.1 3e-19 68.5 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 OAJ13416.1 - 0.0037 16.7 0.6 0.0088 15.5 0.4 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain DnaJ_CXXCXGXG PF00684.14 OAJ13417.1 - 8.1e-05 22.5 4.0 0.035 14.1 0.2 2.3 2 0 0 2 2 2 2 DnaJ central domain PADR1 PF08063.7 OAJ13417.1 - 3.4 7.1 8.6 0.6 9.5 1.0 2.4 3 0 0 3 3 3 0 PADR1 (NUC008) domain PEX11 PF05648.9 OAJ13427.1 - 1.8e-62 210.5 2.1 2e-62 210.3 1.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) FTCD_C PF04961.7 OAJ13427.1 - 0.026 13.9 1.3 0.1 12.0 0.4 2.0 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase DNApol3-delta_C PF09115.5 OAJ13427.1 - 0.083 12.9 0.1 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal GPI-anchored PF10342.4 OAJ13428.1 - 8.4e-13 48.6 1.9 8.4e-13 48.6 1.3 2.4 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1206 PF06724.6 OAJ13428.1 - 0.12 12.1 4.4 0.37 10.5 0.1 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) Pex14_N PF04695.8 OAJ13428.1 - 1.5 8.8 11.4 0.86 9.6 6.1 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DNA_pol_viral_N PF00242.12 OAJ13428.1 - 2.3 7.1 11.6 3.1 6.7 8.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SSP160 PF06933.6 OAJ13428.1 - 3.4 5.5 29.3 6.6 4.5 20.3 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF566 PF04484.7 OAJ13428.1 - 4 6.8 14.2 6.4 6.1 9.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) PAP1 PF08601.5 OAJ13428.1 - 7.3 6.1 17.6 11 5.6 12.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Shisa PF13908.1 OAJ13428.1 - 8.5 6.5 9.3 17 5.5 6.5 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Methyltransf_28 PF02636.12 OAJ13429.1 - 7.5e-33 113.9 0.0 1.4e-32 113.1 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rsm22 PF09243.5 OAJ13429.1 - 7.7e-26 90.7 9.9 1.1e-09 37.7 0.0 5.9 4 2 1 5 5 5 3 Mitochondrial small ribosomal subunit Rsm22 RrnaAD PF00398.15 OAJ13429.1 - 0.0034 16.4 0.0 0.006 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 OAJ13429.1 - 0.055 13.9 0.0 0.33 11.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ13429.1 - 0.075 13.0 1.2 0.43 10.6 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain CPSF100_C PF13299.1 OAJ13430.1 - 3.3e-26 92.4 0.3 1.1e-25 90.6 0.0 2.1 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 OAJ13430.1 - 1.8e-16 60.2 0.0 3.4e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain RVT_1 PF00078.22 OAJ13431.1 - 5.3e-19 68.4 0.0 9.8e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PI3_PI4_kinase PF00454.22 OAJ13443.1 - 1e-46 159.3 0.0 2e-46 158.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 OAJ13443.1 - 3.4e-27 95.1 1.4 6.1e-27 94.2 0.2 2.1 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 OAJ13443.1 - 1.1e-07 31.1 0.0 2.7e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 FATC domain DUF971 PF06155.7 OAJ13443.1 - 0.03 14.7 0.0 0.092 13.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Aminotran_1_2 PF00155.16 OAJ13444.1 - 5.4e-34 117.7 0.0 6.6e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2408 PF10303.4 OAJ13445.1 - 2.3e-52 176.6 0.2 3.2e-35 121.1 0.0 4.8 4 1 1 5 5 5 4 Protein of unknown function (DUF2408) PBP1_TM PF14812.1 OAJ13445.1 - 7.6 6.9 10.7 16 5.8 7.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.8 OAJ13445.1 - 8.9 5.8 11.8 21 4.5 8.2 1.6 1 0 0 1 1 1 0 YL1 nuclear protein Pyridoxal_deC PF00282.14 OAJ13446.1 - 3e-46 157.5 0.0 3.6e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DAO PF01266.19 OAJ13461.1 - 3.1e-17 62.5 0.0 2e-07 30.2 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ13461.1 - 0.00044 20.2 0.3 0.001 19.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAJ13461.1 - 0.00048 19.0 0.0 0.00069 18.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 OAJ13461.1 - 0.0011 18.3 0.1 0.0021 17.5 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 OAJ13461.1 - 0.0022 17.1 0.5 0.0037 16.3 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 OAJ13461.1 - 0.0035 17.7 0.8 0.0068 16.7 0.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 OAJ13461.1 - 0.004 16.5 0.2 0.0075 15.6 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.9 OAJ13461.1 - 0.017 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ13461.1 - 0.051 12.6 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 OAJ13461.1 - 0.13 11.8 0.4 0.31 10.6 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 OAJ13461.1 - 0.15 10.4 0.1 0.22 9.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Linker_histone PF00538.14 OAJ13462.1 - 7.7e-12 45.1 0.1 1.5e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family Peptidase_S15 PF02129.13 OAJ13462.1 - 0.0048 16.3 0.6 0.0067 15.8 0.4 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) MIR PF02815.14 OAJ13464.1 - 1.2e-08 34.7 0.0 3.8e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 MIR domain DHC PF09626.5 OAJ13464.1 - 0.11 13.1 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Dihaem cytochrome c Cu_amine_oxid PF01179.15 OAJ13465.1 - 6e-156 519.3 0.0 7.3e-156 519.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 OAJ13465.1 - 2.5e-14 53.1 0.0 5.8e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 OAJ13465.1 - 0.00046 20.2 0.1 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain TPR_11 PF13414.1 OAJ13478.1 - 1.3e-25 88.8 11.2 9.6e-18 63.6 2.2 2.6 3 0 0 3 3 2 2 TPR repeat TPR_1 PF00515.23 OAJ13478.1 - 9.6e-24 81.9 1.9 5.2e-09 35.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ13478.1 - 6.5e-17 60.0 9.6 1.5e-07 30.8 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ13478.1 - 2.6e-13 49.0 0.2 1.3e-06 28.1 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ13478.1 - 6e-10 39.5 9.2 8.9e-06 26.2 3.3 4.0 2 2 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ13478.1 - 7.6e-10 37.8 1.1 1e-05 24.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ13478.1 - 4.1e-09 35.5 1.8 0.0012 18.4 0.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ13478.1 - 1.7e-08 34.3 5.9 9.7e-06 25.7 0.1 4.9 3 1 3 6 6 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ13478.1 - 2.3e-08 34.2 0.7 0.0013 18.9 0.2 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ13478.1 - 2.1e-07 30.7 1.3 2.1e-07 30.7 0.9 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 OAJ13478.1 - 0.00017 21.6 0.3 0.00031 20.8 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 OAJ13478.1 - 0.00062 19.6 1.9 0.0072 16.2 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ13478.1 - 0.00068 19.4 4.2 0.011 15.5 0.7 3.0 3 1 1 4 4 3 2 Tetratricopeptide repeat RPN7 PF10602.4 OAJ13478.1 - 0.013 14.9 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 T4SS PF07996.6 OAJ13478.1 - 0.015 15.1 0.2 0.015 15.1 0.2 2.7 2 1 0 2 2 2 0 Type IV secretion system proteins Med13_N PF11597.3 OAJ13478.1 - 0.066 11.8 0.8 0.11 11.1 0.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal BTAD PF03704.12 OAJ13478.1 - 0.076 13.3 0.3 0.076 13.3 0.2 3.1 3 1 0 3 3 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 OAJ13478.1 - 0.1 13.1 5.8 2.8 8.5 0.2 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat PPDFL PF15060.1 OAJ13478.1 - 2.1 8.3 7.9 0.7 9.9 0.1 2.7 3 0 0 3 3 2 0 Differentiation and proliferation regulator NARP1 PF12569.3 OAJ13478.1 - 3 6.5 10.6 0.21 10.3 0.4 2.8 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 SR-25 PF10500.4 OAJ13478.1 - 7.6 5.9 12.5 5.2 6.4 1.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Glyco_transf_20 PF00982.16 OAJ13479.1 - 1.8e-142 475.1 0.0 3.3e-142 474.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 OAJ13479.1 - 9.1e-22 77.1 0.0 1.7e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase FAP PF07174.6 OAJ13480.1 - 0.22 10.7 7.5 0.25 10.6 5.2 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) CENP-B_dimeris PF09026.5 OAJ13481.1 - 0.077 13.2 7.0 0.18 12.0 4.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 OAJ13481.1 - 0.39 10.2 4.5 0.69 9.4 3.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 OAJ13481.1 - 0.46 9.7 1.7 0.78 8.9 1.2 1.3 1 0 0 1 1 1 0 NOA36 protein PI3K_1B_p101 PF10486.4 OAJ13481.1 - 1.7 6.0 2.8 2.5 5.5 1.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SnoaL_2 PF12680.2 OAJ13482.1 - 0.048 14.0 0.2 0.081 13.3 0.2 1.4 1 1 0 1 1 1 0 SnoaL-like domain UPF0506 PF11703.3 OAJ13483.1 - 2.2 8.3 24.5 4.1 7.4 1.4 4.4 3 1 1 4 4 4 0 UPF0506 Transposase_21 PF02992.9 OAJ13499.1 - 0.0011 18.0 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 zf-C2H2_2 PF12756.2 OAJ13499.1 - 0.17 11.9 0.4 0.39 10.8 0.1 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Ribosomal_S6e PF01092.14 OAJ13511.1 - 2.8e-57 191.8 0.2 6.1e-57 190.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e DUF2514 PF10721.4 OAJ13512.1 - 0.019 14.6 1.4 0.022 14.4 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Lipase_3 PF01764.20 OAJ13513.1 - 1.9e-12 47.0 0.0 4.5e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Phyto_Pns9_10 PF05878.6 OAJ13513.1 - 4.1 6.3 2.0 7.8 5.4 1.4 1.4 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Ribosomal_S13_N PF08069.7 OAJ13514.1 - 6.1e-30 102.8 0.3 1e-29 102.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 OAJ13514.1 - 2.1e-21 75.4 0.2 2.8e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 OAJ13514.1 - 0.098 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain Fungal_trans PF04082.13 OAJ13515.1 - 1.3e-11 43.8 0.5 0.0001 21.2 0.0 2.8 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ13515.1 - 2.2e-05 24.2 8.8 4.1e-05 23.4 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.4 OAJ13515.1 - 0.061 13.0 0.7 0.13 12.0 0.5 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Tom22 PF04281.8 OAJ13515.1 - 0.48 9.9 0.0 0.48 9.9 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 Adap_comp_sub PF00928.16 OAJ13527.1 - 5.6e-67 225.6 0.1 8.7e-67 224.9 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 OAJ13527.1 - 7.8e-06 25.6 0.8 1.4e-05 24.8 0.3 1.6 1 1 1 2 2 2 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 OAJ13527.1 - 0.022 14.6 0.2 0.046 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) Erf4 PF10256.4 OAJ13528.1 - 1.2e-30 105.7 0.0 1.5e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family RNA_pol_Rpb5_C PF01191.14 OAJ13529.1 - 5e-34 115.7 0.1 9.9e-34 114.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 OAJ13529.1 - 1.9e-30 105.1 0.4 5.8e-30 103.5 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 OAJ13529.1 - 8.6e-05 22.3 0.1 0.00025 20.8 0.0 1.8 2 0 0 2 2 2 1 Restriction endonuclease BLVR PF06375.6 OAJ13529.1 - 0.076 12.8 3.7 0.31 10.8 2.3 1.9 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Ebola_NP PF05505.7 OAJ13529.1 - 0.27 9.2 0.0 0.27 9.2 0.0 2.0 2 0 0 2 2 2 0 Ebola nucleoprotein Abhydrolase_3 PF07859.8 OAJ13530.1 - 2.7e-19 69.5 0.0 5.1e-19 68.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAJ13530.1 - 1.3e-07 30.6 0.0 0.0044 15.7 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 OAJ13530.1 - 0.00015 21.7 1.1 0.00022 21.1 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ13530.1 - 0.00065 19.4 0.0 0.0011 18.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PTPA PF03095.10 OAJ13532.1 - 8e-06 25.2 0.1 1e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein VirDNA-topo-I_N PF09266.5 OAJ13532.1 - 0.13 12.1 0.1 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal AA_permease PF00324.16 OAJ13544.1 - 1.9e-114 382.6 32.6 2.4e-114 382.3 22.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAJ13544.1 - 1.9e-36 125.5 36.0 2.7e-36 125.0 24.9 1.2 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.2 OAJ13544.1 - 0.036 14.2 1.0 0.036 14.2 0.7 4.0 5 0 0 5 5 5 0 PrgI family protein PAP2_3 PF14378.1 OAJ13544.1 - 0.048 13.1 3.7 0.062 12.8 0.5 2.5 2 1 0 2 2 2 0 PAP2 superfamily AhpC-TSA PF00578.16 OAJ13546.1 - 3.8e-06 26.5 0.0 6e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.1 OAJ13546.1 - 4.1e-06 26.6 0.0 6.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 OAJ13546.1 - 1.4e-05 24.6 0.0 0.00015 21.3 0.0 2.0 2 0 0 2 2 2 1 Redoxin WD40 PF00400.27 OAJ13548.1 - 4.2e-08 32.7 4.1 0.0091 15.8 0.1 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat PQQ_2 PF13360.1 OAJ13548.1 - 0.0027 17.2 0.0 0.0062 16.0 0.0 1.5 1 0 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 OAJ13548.1 - 0.014 15.6 0.2 0.072 13.3 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain Kelch_6 PF13964.1 OAJ13548.1 - 0.025 14.7 0.0 12 6.3 0.0 2.8 2 0 0 2 2 2 0 Kelch motif Mito_fiss_reg PF05308.6 OAJ13548.1 - 1.3 8.3 9.9 0.33 10.2 3.8 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator EamA PF00892.15 OAJ13549.1 - 2.3e-22 79.3 32.6 2.2e-15 56.8 4.3 3.9 3 1 1 4 4 4 3 EamA-like transporter family EmrE PF13536.1 OAJ13549.1 - 2.9e-08 33.8 4.7 2.9e-08 33.8 3.2 4.1 3 1 2 5 5 5 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 OAJ13549.1 - 0.00079 18.6 1.2 0.002 17.2 0.8 1.6 1 0 0 1 1 1 1 Nucleotide-sugar transporter DUF1516 PF07457.6 OAJ13549.1 - 0.046 13.8 0.3 0.046 13.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) TPT PF03151.11 OAJ13549.1 - 0.39 10.3 19.7 0.32 10.6 2.7 3.2 3 1 0 3 3 3 0 Triose-phosphate Transporter family DUF3021 PF11457.3 OAJ13549.1 - 1.4 8.7 5.5 0.25 11.2 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) Abhydrolase_4 PF08386.5 OAJ13550.1 - 1.1e-12 47.7 0.0 3.5e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 OAJ13550.1 - 2.6e-09 36.9 0.9 4.9e-08 32.8 0.6 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ13550.1 - 2e-06 27.8 6.6 3.1e-05 23.9 4.6 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ13550.1 - 0.0014 18.3 0.0 0.0058 16.3 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family HABP4_PAI-RBP1 PF04774.10 OAJ13564.1 - 1.1e-05 25.8 2.9 1.1e-05 25.8 2.0 3.6 3 1 1 4 4 4 1 Hyaluronan / mRNA binding family Cyclin_N PF00134.18 OAJ13565.1 - 1.1e-08 34.6 0.0 2.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 OAJ13565.1 - 0.0086 15.8 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C PF02984.14 OAJ13565.1 - 0.051 13.5 0.4 12 5.8 0.0 2.7 2 1 0 2 2 2 0 Cyclin, C-terminal domain ERAP1_C PF11838.3 OAJ13566.1 - 2.9e-62 210.7 0.1 4.3e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.15 OAJ13566.1 - 1.7e-35 122.8 0.1 3e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 OAJ13566.1 - 5.5e-14 52.3 0.0 1.3e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily SNF2_N PF00176.18 OAJ13567.1 - 1.6e-65 220.8 0.0 3.4e-65 219.7 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Rad54_N PF08658.5 OAJ13567.1 - 1.7e-40 138.8 0.0 2.9e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 OAJ13567.1 - 1.3e-10 40.9 0.0 3.5e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 OAJ13567.1 - 4.9e-06 25.5 0.0 2.4e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 OAJ13567.1 - 0.04 13.7 0.0 0.68 9.7 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Cupin_8 PF13621.1 OAJ13568.1 - 0.00039 19.9 0.0 0.00045 19.7 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 OAJ13568.1 - 0.00053 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.6 OAJ13568.1 - 0.00065 19.1 0.2 0.23 10.9 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 OAJ13568.1 - 0.0028 17.0 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 OAJ13568.1 - 0.048 13.2 0.2 0.49 9.9 0.0 2.2 2 1 1 3 3 3 0 Cupin PepSY_2 PF13670.1 OAJ13568.1 - 0.12 12.2 0.2 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain AraC_binding PF02311.14 OAJ13568.1 - 0.12 12.0 0.5 0.29 10.8 0.4 1.8 1 1 0 1 1 1 0 AraC-like ligand binding domain Peptidase_M1 PF01433.15 OAJ13569.1 - 4.3e-67 226.8 0.3 7.6e-40 137.1 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M1 Ribosomal_S9 PF00380.14 OAJ13571.1 - 2e-39 134.5 0.4 2.3e-39 134.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_S3_C PF00189.15 OAJ13572.1 - 1.3e-16 60.5 0.1 2.3e-16 59.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 OAJ13572.1 - 2.4e-09 36.5 0.0 4.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 KH domain HAD_2 PF13419.1 OAJ13585.1 - 5.1e-14 52.8 0.0 3.6e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAJ13585.1 - 2.4e-08 34.6 0.0 8.3e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAJ13585.1 - 0.042 14.0 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 OAJ13585.1 - 0.042 13.7 0.0 8.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Stimulus_sens_1 PF13756.1 OAJ13585.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Stimulus-sensing domain SSrecog PF03531.9 OAJ13586.1 - 1.2e-73 247.1 0.1 2.4e-72 242.8 0.1 2.1 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 OAJ13586.1 - 3.3e-21 75.0 0.3 7.3e-21 73.9 0.0 1.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CDC45 PF02724.9 OAJ13586.1 - 0.0011 17.0 3.4 0.0016 16.5 2.4 1.1 1 0 0 1 1 1 1 CDC45-like protein FH2 PF02181.18 OAJ13587.1 - 3.3e-83 279.6 0.0 4.4e-83 279.2 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain PMI_typeI PF01238.16 OAJ13589.1 - 5.7e-110 367.8 0.0 1.8e-109 366.1 0.0 1.7 1 1 0 1 1 1 1 Phosphomannose isomerase type I DNA_pol_delta_4 PF04081.8 OAJ13601.1 - 1.1e-17 64.4 0.0 1.6e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Cation_efflux PF01545.16 OAJ13602.1 - 1.2e-09 37.7 0.3 2.3e-09 36.7 0.2 1.4 1 0 0 1 1 1 1 Cation efflux family Transposase_20 PF02371.11 OAJ13602.1 - 0.0025 17.8 0.7 0.0055 16.7 0.5 1.5 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family zf-C3HC4 PF00097.20 OAJ13603.1 - 9.4e-09 34.7 1.3 9.4e-09 34.7 0.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ13603.1 - 2.1e-08 34.0 2.0 2.1e-08 34.0 1.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ13603.1 - 2.3e-07 30.3 1.8 3.1e-05 23.5 0.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ13603.1 - 6.1e-07 29.1 4.7 1.2e-06 28.2 0.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 OAJ13603.1 - 5.4e-05 22.8 1.1 0.00011 21.8 0.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 OAJ13603.1 - 0.00021 21.0 2.6 0.00047 19.9 1.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 OAJ13603.1 - 0.00055 19.5 2.7 0.00055 19.5 1.8 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 OAJ13603.1 - 0.2 11.5 3.8 0.3 10.9 0.8 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-B_box PF00643.19 OAJ13603.1 - 0.73 9.7 2.3 1.4 8.8 1.6 1.4 1 0 0 1 1 1 0 B-box zinc finger zf-rbx1 PF12678.2 OAJ13603.1 - 0.92 9.6 1.0 7 6.8 0.2 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger Peptidase_M16 PF00675.15 OAJ13604.1 - 2.2e-51 173.5 2.8 2.3e-50 170.2 1.3 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 OAJ13604.1 - 3.5e-42 144.1 0.0 6.1e-39 133.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain Fe-S_biosyn PF01521.15 OAJ13605.1 - 3.1e-05 23.8 0.0 4.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis ATP-synt_C PF00137.16 OAJ13606.1 - 2.8e-29 100.7 34.8 7.9e-18 64.1 9.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C BRO1 PF03097.13 OAJ13617.1 - 3.5e-17 62.2 0.0 1.2e-13 50.5 0.0 2.0 2 0 0 2 2 2 2 BRO1-like domain Redoxin PF08534.5 OAJ13620.1 - 1.1e-07 31.5 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAJ13620.1 - 9.4e-06 25.3 0.0 8.9e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family FKBP_C PF00254.23 OAJ13621.1 - 4.1e-27 94.0 0.0 8.7e-27 92.9 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2457 PF10446.4 OAJ13621.1 - 0.0064 15.2 16.0 0.0064 15.2 11.1 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 OAJ13621.1 - 0.013 15.7 10.4 0.013 15.7 7.2 4.2 4 1 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Daxx PF03344.10 OAJ13621.1 - 0.7 8.3 34.9 0.42 9.0 12.4 2.1 2 0 0 2 2 2 0 Daxx Family DUF812 PF05667.6 OAJ13621.1 - 2.8 6.3 11.8 3.8 5.9 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Macoilin PF09726.4 OAJ13621.1 - 3.8 5.6 12.0 5.3 5.2 8.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DPBB_1 PF03330.13 OAJ13622.1 - 1.4e-09 37.8 0.1 2.9e-09 36.8 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ13622.1 - 0.087 12.5 0.5 0.16 11.6 0.4 1.5 1 1 0 1 1 1 0 Barwin family KH_1 PF00013.24 OAJ13623.1 - 1.2e-82 271.4 33.9 1.5e-12 46.9 0.1 13.7 13 1 0 13 13 13 11 KH domain KH_3 PF13014.1 OAJ13623.1 - 9.5e-61 200.6 21.9 3.8e-08 32.7 0.0 11.8 11 0 0 11 11 11 10 KH domain KH_2 PF07650.12 OAJ13623.1 - 7.7e-11 41.4 27.4 0.3 10.6 0.3 9.4 9 1 1 10 10 10 6 KH domain KH_4 PF13083.1 OAJ13623.1 - 0.00013 21.5 22.5 0.056 13.0 0.1 8.8 7 1 2 9 9 9 3 KH domain DUF1212 PF06738.7 OAJ13642.1 - 3.4e-33 114.7 14.7 1.4e-32 112.7 1.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 OAJ13642.1 - 8e-19 67.8 11.6 8e-19 67.8 8.1 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3815) EcsB PF05975.7 OAJ13642.1 - 2.4 6.5 8.7 0.24 9.8 1.9 2.0 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB HSP90 PF00183.13 OAJ13643.1 - 1.3e-98 330.7 0.2 1.4e-98 330.6 0.2 1.0 1 0 0 1 1 1 1 Hsp90 protein HBS1_N PF08938.5 OAJ13643.1 - 0.058 13.5 0.2 0.14 12.2 0.2 1.7 1 0 0 1 1 1 0 HBS1 N-terminus DUF399 PF04187.8 OAJ13643.1 - 0.069 12.6 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF399 Ubiq-assoc PF09145.5 OAJ13643.1 - 0.07 13.0 0.1 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-associated HSP90 PF00183.13 OAJ13644.1 - 1.1e-47 162.6 1.0 1.3e-47 162.4 0.7 1.0 1 0 0 1 1 1 1 Hsp90 protein LOH1CR12 PF10158.4 OAJ13644.1 - 0.019 14.7 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 Tumour suppressor protein Tyrosinase PF00264.15 OAJ13645.1 - 1.1e-33 117.3 2.1 1.1e-33 117.3 1.5 2.1 2 0 0 2 2 2 1 Common central domain of tyrosinase Adaptin_binding PF10199.4 OAJ13645.1 - 0.00088 19.5 10.7 0.00088 19.5 7.4 1.9 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Med19 PF10278.4 OAJ13645.1 - 0.019 14.6 10.5 0.028 14.0 7.3 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RNA_polI_A34 PF08208.6 OAJ13645.1 - 0.036 13.7 20.2 0.054 13.1 14.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Cellulose_synt PF03552.9 OAJ13645.1 - 0.22 9.7 2.5 0.31 9.2 1.7 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF4175 PF13779.1 OAJ13645.1 - 2.7 5.5 19.4 3.5 5.1 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Nucleo_P87 PF07267.6 OAJ13645.1 - 3 6.4 10.6 4.2 5.9 7.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RR_TM4-6 PF06459.7 OAJ13645.1 - 3.3 7.5 19.9 4.9 6.9 13.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_Ag35 PF03286.9 OAJ13645.1 - 9.7 5.6 25.7 15 5.0 17.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HSP90 PF00183.13 OAJ13646.1 - 3.7e-99 332.5 0.3 4.2e-99 332.3 0.2 1.0 1 0 0 1 1 1 1 Hsp90 protein HBS1_N PF08938.5 OAJ13646.1 - 0.055 13.5 0.2 0.14 12.2 0.2 1.7 1 0 0 1 1 1 0 HBS1 N-terminus DUF399 PF04187.8 OAJ13646.1 - 0.069 12.6 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF399 Ubiq-assoc PF09145.5 OAJ13646.1 - 0.07 13.0 0.1 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-associated DUF1212 PF06738.7 OAJ13647.1 - 3.4e-33 114.7 14.7 1.4e-32 112.7 1.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 OAJ13647.1 - 8e-19 67.8 11.6 8e-19 67.8 8.1 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3815) EcsB PF05975.7 OAJ13647.1 - 2.4 6.5 8.7 0.24 9.8 1.9 2.0 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB TPR_12 PF13424.1 OAJ13663.1 - 2.4e-10 40.2 18.2 0.0043 16.9 0.0 6.6 6 3 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ13663.1 - 7.4e-10 38.3 8.3 0.0021 17.6 0.4 5.2 4 2 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 OAJ13663.1 - 5.6e-09 35.2 6.0 0.76 9.8 0.3 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ13663.1 - 1.7e-05 24.2 0.0 9.9 6.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ13663.1 - 0.00044 20.8 15.9 0.014 16.0 1.3 5.6 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ13663.1 - 0.0005 19.6 2.2 0.47 10.3 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ13663.1 - 0.00094 18.6 1.8 5 6.9 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3856 PF12968.2 OAJ13663.1 - 0.0018 18.0 1.3 0.0068 16.2 0.2 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_14 PF13428.1 OAJ13663.1 - 0.011 16.3 26.2 10 7.0 0.0 8.8 7 3 3 10 10 9 0 Tetratricopeptide repeat DSHCT PF08148.7 OAJ13663.1 - 0.011 14.9 0.1 0.092 11.9 0.0 2.4 2 0 0 2 2 2 0 DSHCT (NUC185) domain TPR_6 PF13174.1 OAJ13663.1 - 0.013 15.9 6.1 0.89 10.1 0.0 4.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ13663.1 - 0.016 15.5 12.5 0.1 12.9 0.9 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 OAJ13663.1 - 1.3 8.9 6.5 25 4.8 0.0 4.6 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain SF3b1 PF08920.5 OAJ13664.1 - 8.4e-30 103.7 0.5 3.4e-29 101.7 0.0 2.2 2 1 0 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 OAJ13664.1 - 7.4e-17 61.4 5.4 1.1e-05 25.6 0.1 7.4 6 2 4 10 10 10 5 HEAT repeats HEAT_EZ PF13513.1 OAJ13664.1 - 6.3e-12 45.6 5.0 0.13 12.8 0.0 8.1 7 3 2 9 9 9 3 HEAT-like repeat HEAT PF02985.17 OAJ13664.1 - 5.1e-09 35.4 6.7 0.66 10.2 0.1 9.5 10 0 0 10 10 10 1 HEAT repeat Adaptin_N PF01602.15 OAJ13664.1 - 8.8e-08 30.9 0.6 0.00063 18.1 0.0 3.0 1 1 1 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 OAJ13664.1 - 8.7e-06 26.0 0.3 0.94 9.9 0.0 5.3 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 OAJ13664.1 - 0.00019 20.8 0.3 0.57 9.4 0.0 3.7 4 0 0 4 4 4 1 CLASP N terminal NUC173 PF08161.7 OAJ13664.1 - 0.00041 19.7 0.2 2.6 7.3 0.0 4.1 3 1 1 4 4 4 1 NUC173 domain Dopey_N PF04118.9 OAJ13664.1 - 0.01 14.6 0.5 0.1 11.3 0.0 2.7 3 0 0 3 3 3 0 Dopey, N-terminal MMS19_N PF14500.1 OAJ13664.1 - 0.013 14.7 0.0 27 3.8 0.0 3.6 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 OAJ13664.1 - 0.051 12.2 0.0 26 3.3 0.0 3.9 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal Hpt PF01627.18 OAJ13665.1 - 0.047 13.7 1.5 0.21 11.6 0.5 2.1 1 1 1 2 2 2 0 Hpt domain PgaD PF13994.1 OAJ13665.1 - 0.13 11.7 0.1 0.43 10.0 0.0 1.8 1 1 1 2 2 2 0 PgaD-like protein BAR_3_WASP_bdg PF10456.4 OAJ13665.1 - 0.15 11.3 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein Nro1 PF12753.2 OAJ13666.1 - 0.0047 15.9 0.8 0.0055 15.7 0.5 1.1 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 NAD_binding_9 PF13454.1 OAJ13666.1 - 0.024 14.4 0.7 0.038 13.7 0.5 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF4238 PF14022.1 OAJ13666.1 - 0.1 11.8 0.1 0.11 11.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) AKNA PF12443.3 OAJ13666.1 - 0.15 12.1 1.5 0.27 11.2 1.1 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor DUF1127 PF06568.6 OAJ13666.1 - 0.18 11.2 0.1 0.18 11.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) FdhE PF04216.7 OAJ13666.1 - 0.19 11.4 3.2 0.22 11.2 1.9 1.3 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation Atg14 PF10186.4 OAJ13666.1 - 0.2 10.5 5.4 0.21 10.4 3.2 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tox-ODYAM1 PF15642.1 OAJ13666.1 - 0.26 9.9 2.4 0.32 9.5 1.7 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus ubiquitin PF00240.18 OAJ13667.1 - 1.5e-29 101.1 0.4 1.7e-11 43.3 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 OAJ13667.1 - 1.4e-16 59.8 0.3 1.5e-07 31.0 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF4634 PF15465.1 OAJ13667.1 - 0.0088 16.2 0.3 0.044 13.9 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4634) USP7_C2 PF14533.1 OAJ13667.1 - 0.048 13.0 0.3 0.54 9.6 0.1 2.4 2 1 1 3 3 3 0 Ubiquitin-specific protease C-terminal FlgD_ig PF13860.1 OAJ13667.1 - 0.081 12.6 0.4 11 5.8 0.0 2.4 2 0 0 2 2 2 0 FlgD Ig-like domain ADK_lid PF05191.9 OAJ13681.1 - 8.4 6.1 9.2 3.1 7.5 3.9 2.2 2 1 0 2 2 2 0 Adenylate kinase, active site lid RNA_pol_3_Rpc31 PF11705.3 OAJ13682.1 - 0.0031 17.4 2.3 0.0031 17.4 1.6 2.3 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 DUF4611 PF15387.1 OAJ13682.1 - 0.046 13.8 15.6 0.79 9.9 2.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 OAJ13682.1 - 0.083 12.4 19.8 0.11 11.9 2.8 2.2 2 0 0 2 2 2 0 Nucleoplasmin Vfa1 PF08432.5 OAJ13682.1 - 0.095 12.7 3.2 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RXT2_N PF08595.6 OAJ13682.1 - 1.1 9.0 11.9 1.7 8.4 0.9 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.1 OAJ13682.1 - 2.2 7.9 7.0 1.4 8.5 0.2 2.4 2 0 0 2 2 2 0 FAM176 family PPP4R2 PF09184.6 OAJ13682.1 - 2.6 7.5 12.0 5.1 6.5 1.9 2.2 2 0 0 2 2 2 0 PPP4R2 Voldacs PF03517.8 OAJ13682.1 - 2.9 7.7 9.5 2.7 7.8 0.9 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Nop25 PF09805.4 OAJ13682.1 - 3.2 7.8 8.5 2.5 8.1 0.3 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) ANAPC15 PF15243.1 OAJ13682.1 - 3.9 7.6 19.8 2 8.5 3.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Cwf_Cwc_15 PF04889.7 OAJ13682.1 - 8.4 6.0 18.4 4.8 6.8 4.7 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein AAA_2 PF07724.9 OAJ13683.1 - 7.9e-46 156.0 0.0 7.1e-44 149.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 OAJ13683.1 - 1e-23 83.9 0.0 2.7e-12 47.0 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 OAJ13683.1 - 1e-21 76.5 0.1 4.5e-21 74.5 0.0 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 OAJ13683.1 - 5.6e-14 52.0 0.0 1.1e-07 31.6 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 OAJ13683.1 - 1.3e-12 47.4 3.0 3.5e-06 26.8 0.5 3.8 3 0 0 3 3 3 2 Clp amino terminal domain AAA_16 PF13191.1 OAJ13683.1 - 7.2e-11 42.4 0.1 2.1e-07 31.0 0.0 5.8 5 3 1 7 7 6 2 AAA ATPase domain AAA_22 PF13401.1 OAJ13683.1 - 2.7e-10 40.4 1.5 0.002 18.2 0.0 4.6 3 2 1 4 4 3 2 AAA domain IstB_IS21 PF01695.12 OAJ13683.1 - 6.2e-08 32.2 0.0 0.016 14.6 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_17 PF13207.1 OAJ13683.1 - 4.5e-07 30.7 4.2 0.0093 16.7 0.0 4.0 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.1 OAJ13683.1 - 2e-06 28.1 0.5 0.16 12.2 0.0 3.4 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 OAJ13683.1 - 4e-06 26.4 0.0 0.0025 17.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 OAJ13683.1 - 1.5e-05 24.8 0.1 0.025 14.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 OAJ13683.1 - 6.5e-05 23.0 0.0 0.22 11.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.8 OAJ13683.1 - 7.9e-05 21.7 0.0 0.45 9.3 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF815) AAA_19 PF13245.1 OAJ13683.1 - 8.7e-05 22.2 0.1 0.089 12.5 0.1 3.1 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 OAJ13683.1 - 0.00011 21.3 0.0 0.023 13.7 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin Arch_ATPase PF01637.13 OAJ13683.1 - 0.00022 20.9 8.3 0.038 13.6 0.0 5.1 4 2 1 6 6 6 1 Archaeal ATPase DUF258 PF03193.11 OAJ13683.1 - 0.00023 20.4 0.0 0.53 9.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 OAJ13683.1 - 0.00029 20.5 0.0 0.34 10.6 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 OAJ13683.1 - 0.00031 20.4 0.0 0.17 11.5 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.1 OAJ13683.1 - 0.00071 19.2 0.0 0.65 9.5 0.0 3.0 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.16 OAJ13683.1 - 0.00075 18.7 0.0 0.18 10.9 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 OAJ13683.1 - 0.00093 19.1 2.7 0.78 9.6 0.0 3.6 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 OAJ13683.1 - 0.0013 17.8 0.0 0.21 10.5 0.0 2.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 OAJ13683.1 - 0.0015 17.9 1.6 1.5 8.1 0.0 4.2 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.22 OAJ13683.1 - 0.0034 17.6 0.4 1.6 9.0 0.0 3.4 3 0 0 3 3 3 1 ABC transporter NTPase_1 PF03266.10 OAJ13683.1 - 0.0035 17.0 0.0 2.2 7.9 0.0 2.9 3 0 0 3 3 2 1 NTPase AAA_29 PF13555.1 OAJ13683.1 - 0.0038 16.7 0.0 3.2 7.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.17 OAJ13683.1 - 0.0039 16.6 0.0 0.67 9.3 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_10 PF12846.2 OAJ13683.1 - 0.0065 15.9 2.0 3.5 6.9 0.0 3.7 4 1 1 5 5 5 1 AAA-like domain ATP_bind_1 PF03029.12 OAJ13683.1 - 0.011 15.3 0.0 0.88 9.0 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 OAJ13683.1 - 0.018 14.6 0.0 7 6.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 OAJ13683.1 - 0.044 13.3 0.0 14 5.2 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 OAJ13683.1 - 0.059 13.8 0.0 4.6 7.7 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Rsa3 PF14615.1 OAJ13683.1 - 0.11 11.7 2.6 1.6 8.0 0.3 2.7 2 0 0 2 2 2 0 Ribosome-assembly protein 3 PduV-EutP PF10662.4 OAJ13683.1 - 0.13 11.7 0.0 3 7.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 OAJ13683.1 - 0.15 12.3 0.0 0.15 12.3 0.0 3.6 4 1 0 4 4 2 0 AAA domain AAA_21 PF13304.1 OAJ13683.1 - 0.16 11.9 0.0 31 4.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain Tht1 PF04163.7 OAJ13683.1 - 0.4 9.0 0.1 0.65 8.3 0.1 1.2 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein AAA_13 PF13166.1 OAJ13683.1 - 0.42 9.0 6.1 0.71 8.2 4.2 1.3 1 0 0 1 1 1 0 AAA domain bZIP_1 PF00170.16 OAJ13685.1 - 9.9e-11 41.4 3.2 1.7e-10 40.7 2.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor Aft1_HRA PF11786.3 OAJ13685.1 - 3.3e-09 36.8 22.3 3.3e-09 36.8 15.4 5.0 3 1 0 3 3 3 1 Aft1 HRA domain bZIP_2 PF07716.10 OAJ13685.1 - 4.6e-07 29.5 5.7 1e-06 28.4 3.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Nop53 PF07767.6 OAJ13685.1 - 0.017 14.0 3.1 0.036 13.0 2.2 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.9 OAJ13685.1 - 0.35 8.8 3.8 0.71 7.8 2.6 1.4 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 OAJ13686.1 - 6.3e-17 60.7 12.2 4.7e-09 35.7 0.8 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 OAJ13686.1 - 1.9e-06 27.7 0.0 0.018 14.7 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 OAJ13686.1 - 5.9e-05 22.6 0.1 0.013 14.9 0.0 2.9 3 0 0 3 3 3 1 PQQ-like domain PQQ_3 PF13570.1 OAJ13686.1 - 0.0012 19.0 0.0 0.14 12.4 0.0 2.9 2 0 0 2 2 2 1 PQQ-like domain Mito_fiss_reg PF05308.6 OAJ13686.1 - 0.0044 16.4 2.8 0.0044 16.4 1.9 1.6 2 0 0 2 2 2 1 Mitochondrial fission regulator Kelch_4 PF13418.1 OAJ13686.1 - 0.022 14.4 0.1 2.5 7.9 0.0 2.9 2 0 0 2 2 2 0 Galactose oxidase, central domain LigD_N PF13298.1 OAJ13686.1 - 0.092 12.8 0.1 1.9 8.6 0.0 2.7 2 1 1 3 3 3 0 DNA polymerase Ligase (LigD) Cytochrom_D1 PF02239.11 OAJ13686.1 - 0.12 10.6 0.0 5.4 5.2 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain ADH_zinc_N PF00107.21 OAJ13700.1 - 1.3e-35 121.7 0.2 2.2e-35 121.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ13700.1 - 1.1e-12 48.9 0.0 2.3e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ13700.1 - 2.7e-06 27.0 0.0 1.1e-05 25.1 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 OAJ13700.1 - 0.018 14.6 0.1 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ribosomal_L4 PF00573.17 OAJ13702.1 - 3.9e-60 202.5 0.0 6.6e-60 201.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Thioredoxin_3 PF13192.1 OAJ13702.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain DUF3591 PF12157.3 OAJ13703.1 - 5.4e-170 565.7 0.1 7e-170 565.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 OAJ13703.1 - 1.4e-05 24.6 3.5 3.5e-05 23.3 2.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 OAJ13703.1 - 0.096 12.6 2.0 0.16 11.9 1.4 1.3 1 0 0 1 1 1 0 Zinc knuckle Amidohydro_4 PF13147.1 OAJ13706.1 - 4.8e-09 36.6 3.0 9.3e-08 32.4 0.4 2.2 1 1 0 2 2 2 2 Amidohydrolase Amidohydro_2 PF04909.9 OAJ13706.1 - 5.6e-06 26.1 0.9 1.3e-05 24.9 0.3 2.0 1 1 1 2 2 2 1 Amidohydrolase TFIIE-A_C-term PF11521.3 OAJ13730.1 - 0.48 10.4 3.4 0.3 11.0 0.7 1.8 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Formyl_trans_N PF00551.14 OAJ13731.1 - 3.2e-30 104.9 0.0 4.4e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 OAJ13731.1 - 3.6e-08 32.7 0.0 9e-08 31.4 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 OAJ13731.1 - 0.0001 21.9 0.2 0.00028 20.5 0.0 1.8 2 0 0 2 2 2 1 ACT domain DUF3722 PF12519.3 OAJ13732.1 - 1.4e-81 273.5 4.4 3.4e-80 269.0 0.2 3.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 OAJ13732.1 - 0.00011 21.6 0.1 0.00053 19.3 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic porin PAT1 PF09770.4 OAJ13732.1 - 1.5 6.9 14.0 3.5 5.7 0.2 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 OAJ13732.1 - 2.7 7.2 34.7 0.094 12.0 9.1 2.2 2 0 0 2 2 2 0 Vta1 like Septin PF00735.13 OAJ13733.1 - 1.5e-107 358.7 0.0 1.5e-107 358.7 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 OAJ13733.1 - 3.4e-07 30.2 0.0 7.2e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 OAJ13733.1 - 0.00024 20.9 5.4 0.046 13.5 0.1 3.1 2 1 1 3 3 3 2 Dynamin family AAA_17 PF13207.1 OAJ13733.1 - 0.00039 21.2 3.9 0.0052 17.5 2.7 2.6 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 OAJ13733.1 - 0.00041 19.8 0.1 0.0099 15.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 OAJ13733.1 - 0.00054 20.1 0.0 0.0028 17.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 OAJ13733.1 - 0.0006 19.0 0.4 0.003 16.7 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 OAJ13733.1 - 0.0012 18.8 1.4 0.047 13.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 OAJ13733.1 - 0.0013 19.2 0.0 0.0038 17.7 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 OAJ13733.1 - 0.0014 18.1 0.4 0.0032 16.9 0.1 1.6 2 0 0 2 2 1 1 FtsK/SpoIIIE family AIG1 PF04548.11 OAJ13733.1 - 0.0022 17.1 0.1 0.0044 16.1 0.0 1.6 1 1 0 1 1 1 1 AIG1 family AAA_33 PF13671.1 OAJ13733.1 - 0.0031 17.3 0.4 0.0086 15.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 OAJ13733.1 - 0.0047 16.6 0.0 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.8 OAJ13733.1 - 0.0057 15.5 0.1 0.014 14.2 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 OAJ13733.1 - 0.011 15.9 0.4 0.035 14.4 0.0 2.0 2 1 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.12 OAJ13733.1 - 0.026 14.0 0.4 1 8.8 0.2 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IncA PF04156.9 OAJ13733.1 - 0.045 13.3 4.3 0.075 12.6 3.0 1.3 1 0 0 1 1 1 0 IncA protein cobW PF02492.14 OAJ13733.1 - 0.055 12.9 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AbiH PF14253.1 OAJ13733.1 - 0.063 12.8 1.1 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH AAA_19 PF13245.1 OAJ13733.1 - 0.07 12.8 0.2 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 OAJ13733.1 - 0.084 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 OAJ13733.1 - 0.088 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 OAJ13733.1 - 0.093 12.1 0.3 0.27 10.6 0.1 1.7 1 1 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.4 OAJ13733.1 - 0.1 12.0 0.3 0.32 10.4 0.0 1.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 OAJ13733.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.1 OAJ13733.1 - 0.12 12.6 5.5 0.081 13.2 0.7 2.9 1 1 2 3 3 3 0 AAA domain Ras PF00071.17 OAJ13733.1 - 0.15 11.4 0.7 0.48 9.8 0.0 2.2 3 0 0 3 3 3 0 Ras family OmpH PF03938.9 OAJ13733.1 - 0.17 11.7 4.5 0.35 10.8 3.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF87 PF01935.12 OAJ13733.1 - 0.46 10.2 5.2 0.61 9.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Atg14 PF10186.4 OAJ13733.1 - 0.67 8.8 6.3 0.97 8.3 4.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TIP120 PF08623.5 OAJ13734.1 - 4.5e-51 172.7 5.2 4.6e-50 169.4 0.1 3.6 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 OAJ13734.1 - 8.6e-24 83.6 26.0 0.0044 17.2 0.0 9.7 6 3 2 8 8 8 7 HEAT repeats HEAT PF02985.17 OAJ13734.1 - 8.4e-11 41.0 27.6 0.65 10.2 0.1 12.3 14 1 1 15 15 12 3 HEAT repeat HEAT_EZ PF13513.1 OAJ13734.1 - 5.9e-08 32.9 45.3 0.55 10.7 0.0 13.8 12 3 3 15 15 15 4 HEAT-like repeat Adaptin_N PF01602.15 OAJ13734.1 - 7.4e-07 27.8 21.2 0.00038 18.9 0.2 6.5 2 2 3 5 5 5 3 Adaptin N terminal region UME PF08064.8 OAJ13734.1 - 2.4e-06 27.4 1.3 4.8 7.1 0.0 5.9 6 1 1 7 7 6 2 UME (NUC010) domain Vac14_Fab1_bd PF12755.2 OAJ13734.1 - 0.0004 20.7 0.8 3.6 8.0 0.1 6.9 8 1 1 9 9 8 1 Vacuolar 14 Fab1-binding region Pex16 PF08610.5 OAJ13734.1 - 0.0027 16.7 0.0 0.078 11.9 0.0 2.4 2 0 0 2 2 2 1 Peroxisomal membrane protein (Pex16) SporV_AA PF12164.3 OAJ13734.1 - 0.057 13.4 0.1 13 5.8 0.0 2.8 2 0 0 2 2 2 0 Stage V sporulation protein AA RRN3 PF05327.6 OAJ13734.1 - 0.071 11.2 5.0 0.076 11.1 1.1 2.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Upf2 PF04050.9 OAJ13734.1 - 0.089 12.5 7.1 0.18 11.5 5.0 1.4 1 0 0 1 1 1 0 Up-frameshift suppressor 2 DUF3385 PF11865.3 OAJ13734.1 - 0.11 12.4 5.8 4 7.3 0.0 4.9 5 1 1 6 6 6 0 Domain of unknown function (DUF3385) CDC45 PF02724.9 OAJ13734.1 - 1.4 6.8 7.6 0.88 7.5 2.8 2.0 2 0 0 2 2 2 0 CDC45-like protein DUF616 PF04765.8 OAJ13735.1 - 0.041 13.0 0.2 0.059 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF616) Octopine_DH PF02317.12 OAJ13735.1 - 0.088 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain KaiC PF06745.8 OAJ13735.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 KaiC zf-CCHC_4 PF14392.1 OAJ13735.1 - 7.2 6.3 8.9 0.55 9.9 1.4 2.2 2 0 0 2 2 2 0 Zinc knuckle Phage_integrase PF00589.17 OAJ13737.1 - 2.4e-05 24.0 0.0 4e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 OAJ13737.1 - 0.0022 18.0 0.0 0.0085 16.2 0.0 2.0 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DUF3752 PF12572.3 OAJ13738.1 - 5.2e-11 42.8 16.4 5.2e-11 42.8 11.4 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF3752) Fungal_trans PF04082.13 OAJ13756.1 - 2.3e-18 65.9 0.4 5.1e-18 64.8 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ13756.1 - 1.7e-07 30.9 9.9 2.7e-07 30.3 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3074 PF11274.3 OAJ13757.1 - 1.2e-44 152.1 0.0 1.6e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) AAA_13 PF13166.1 OAJ13759.1 - 0.27 9.6 2.4 0.46 8.8 1.6 1.2 1 0 0 1 1 1 0 AAA domain rve PF00665.21 OAJ13777.1 - 1.8e-22 79.7 0.0 6.3e-22 77.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ13777.1 - 5.8e-07 29.9 0.0 1.4e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ13777.1 - 8.8e-06 25.4 0.0 0.00012 21.8 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease MIP-T3 PF10243.4 OAJ13777.1 - 0.0033 15.9 12.4 0.0054 15.2 8.6 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 RVP PF00077.15 OAJ13777.1 - 0.0048 16.7 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.5 OAJ13777.1 - 0.012 14.9 0.3 0.032 13.6 0.2 1.8 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger DUF2201_N PF13203.1 OAJ13777.1 - 0.024 13.8 10.3 0.042 13.0 7.2 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain zf-CCHC PF00098.18 OAJ13777.1 - 0.083 12.8 4.6 0.19 11.7 3.2 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_3 PF13456.1 OAJ13777.1 - 0.15 11.9 0.0 0.43 10.3 0.0 1.8 1 0 0 1 1 1 0 Reverse transcriptase-like RVT_1 PF00078.22 OAJ13777.1 - 0.16 11.2 0.0 0.58 9.4 0.0 2.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF605 PF04652.11 OAJ13777.1 - 0.39 10.0 33.0 0.11 11.9 11.0 2.3 2 0 0 2 2 2 0 Vta1 like TFIIF_alpha PF05793.7 OAJ13777.1 - 3.8 5.7 31.2 6.7 4.9 21.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hid1 PF12722.2 OAJ13777.1 - 4.7 4.7 8.2 7.5 4.0 5.7 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Transposase_21 PF02992.9 OAJ13778.1 - 0.0081 15.2 0.1 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Ribonuclease_3 PF00636.21 OAJ13780.1 - 3.8e-10 40.2 0.1 4.2e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 OAJ13780.1 - 6.4e-05 22.9 0.4 0.00028 20.8 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease-III-like GCR1_C PF12550.3 OAJ13787.1 - 3.2e-19 68.5 0.4 7.3e-19 67.4 0.3 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Phage_int_SAM_1 PF02899.12 OAJ13787.1 - 0.029 14.5 6.5 11 6.2 0.0 4.7 4 1 1 5 5 5 0 Phage integrase, N-terminal SAM-like domain Xpo1 PF08389.7 OAJ13787.1 - 0.031 14.1 0.2 0.066 13.1 0.1 1.5 1 0 0 1 1 1 0 Exportin 1-like protein Fzo_mitofusin PF04799.8 OAJ13787.1 - 0.08 12.3 1.2 0.17 11.2 0.8 1.5 1 0 0 1 1 1 0 fzo-like conserved region DDE_Tnp_4 PF13359.1 OAJ13788.1 - 0.004 16.7 0.0 0.005 16.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ13788.1 - 0.037 13.4 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein RVT_1 PF00078.22 OAJ13789.1 - 2.7e-20 72.6 0.0 9.2e-20 70.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ13789.1 - 0.00017 21.7 0.0 0.00058 19.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain MULE PF10551.4 OAJ13790.1 - 1.2e-18 67.0 0.0 3.2e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.10 OAJ13790.1 - 2e-14 52.9 0.7 5.1e-14 51.5 0.5 1.6 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.13 OAJ13790.1 - 3.1e-08 32.5 0.0 5.7e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family zf-CCHC PF00098.18 OAJ13790.1 - 0.11 12.4 1.9 0.34 10.9 1.3 1.9 1 0 0 1 1 1 0 Zinc knuckle Apolipoprotein PF01442.13 OAJ13801.1 - 0.018 14.5 2.0 0.018 14.5 1.4 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DASH_Dad2 PF08654.5 OAJ13801.1 - 0.045 13.7 0.7 0.045 13.7 0.5 2.2 1 1 1 2 2 2 0 DASH complex subunit Dad2 DUF883 PF05957.8 OAJ13801.1 - 0.4 11.1 5.7 3.1 8.2 1.3 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) OmpH PF03938.9 OAJ13801.1 - 0.45 10.4 7.2 4.5 7.1 0.0 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.7 OAJ13801.1 - 2 8.7 5.3 30 4.9 3.6 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.11 OAJ13802.1 - 0.00023 19.9 0.3 0.00026 19.8 0.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily RRM_1 PF00076.17 OAJ13804.1 - 2.5e-17 62.2 0.0 2.3e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ13804.1 - 2.6e-10 39.9 0.0 2e-07 30.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ13804.1 - 5.4e-07 29.5 0.0 5.2e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 OAJ13805.1 - 3.7e-33 114.2 0.0 4.2e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ13805.1 - 2.3e-13 50.6 0.0 2.6e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ13805.1 - 2e-08 33.6 0.0 2.2e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 OAJ13805.1 - 0.00039 20.3 0.0 0.00045 20.1 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 OAJ13805.1 - 0.0004 19.5 0.0 0.00047 19.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 OAJ13805.1 - 0.026 13.7 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 G-alpha PF00503.15 OAJ13805.1 - 0.041 12.5 0.1 4.2 5.9 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.1 OAJ13805.1 - 0.052 13.5 0.0 0.062 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 OAJ13805.1 - 0.092 12.8 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Aldo_ket_red PF00248.16 OAJ13806.1 - 2.9e-49 167.3 0.0 3.8e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Slx4 PF09494.5 OAJ13806.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Slx4 endonuclease Aldo_ket_red PF00248.16 OAJ13807.1 - 4.8e-67 225.7 0.0 6.5e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.7 OAJ13824.1 - 2.3e-25 88.4 0.6 4.4e-25 87.5 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ13824.1 - 2.3e-21 75.6 0.1 3.6e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ13824.1 - 0.015 16.1 0.0 0.036 14.9 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 OAJ13824.1 - 0.019 14.6 0.1 0.031 13.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 OAJ13824.1 - 0.023 13.1 0.2 0.032 12.7 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 OAJ13824.1 - 0.039 13.3 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 OAJ13824.1 - 0.04 14.4 0.0 0.092 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AAA PF00004.24 OAJ13826.1 - 6.1e-14 52.3 0.0 9.6e-13 48.4 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ13826.1 - 4.3e-08 33.3 0.0 4.3e-08 33.3 0.0 3.3 3 2 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 OAJ13826.1 - 7.3e-07 29.3 0.0 4.7e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ13826.1 - 5e-05 22.9 3.8 0.00037 20.2 0.0 3.1 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 OAJ13826.1 - 0.019 14.6 0.2 6.9 6.2 0.0 3.3 2 1 0 2 2 2 0 Archaeal ATPase Viral_NABP PF05515.6 OAJ13826.1 - 0.034 14.4 0.4 0.087 13.1 0.3 1.6 1 0 0 1 1 1 0 Viral nucleic acid binding NACHT PF05729.7 OAJ13826.1 - 0.057 13.0 0.0 0.4 10.3 0.0 2.1 1 1 0 1 1 1 0 NACHT domain AAA_11 PF13086.1 OAJ13826.1 - 0.062 12.8 1.8 0.094 12.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF2673 PF10880.3 OAJ13826.1 - 0.072 13.1 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) GluR_Homer-bdg PF10606.4 OAJ13826.1 - 0.11 12.4 2.7 0.078 12.8 0.3 1.9 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor CDC45 PF02724.9 OAJ13826.1 - 3 5.7 10.4 5.6 4.8 7.2 1.4 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 OAJ13826.1 - 3.3 6.6 21.1 7.5 5.5 14.6 1.5 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 OAJ13826.1 - 4 5.2 17.8 6 4.6 12.3 1.2 1 0 0 1 1 1 0 Nop14-like family Sad1_UNC PF07738.8 OAJ13827.1 - 5.8e-22 77.9 0.0 4e-10 39.6 0.0 3.8 2 2 0 2 2 2 2 Sad1 / UNC-like C-terminal Mgr1 PF08602.5 OAJ13827.1 - 0.12 11.3 2.6 0.19 10.6 1.8 1.4 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit AAA_13 PF13166.1 OAJ13827.1 - 0.3 9.4 12.0 0.58 8.5 8.3 1.4 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 OAJ13827.1 - 0.47 9.5 11.9 0.32 10.1 2.0 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 OAJ13827.1 - 2.4 8.2 6.7 1.4 9.0 1.8 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 OAJ13827.1 - 3.7 7.3 10.6 4.5 7.0 0.3 3.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 OAJ13827.1 - 9.1 5.6 23.7 3.2 7.1 3.6 2.8 2 1 1 3 3 3 0 Intermediate filament protein F-box-like PF12937.2 OAJ13828.1 - 0.0016 18.0 0.1 0.0074 15.9 0.0 2.2 2 0 0 2 2 2 1 F-box-like SPT2 PF08243.6 OAJ13829.1 - 1.6e-17 63.8 1.2 1.6e-17 63.8 0.8 5.3 5 0 0 5 5 5 1 SPT2 chromatin protein Neur_chan_memb PF02932.11 OAJ13830.1 - 8 6.2 10.8 12 5.6 2.1 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Acatn PF13000.2 OAJ13840.1 - 1.3e-141 472.7 29.6 6e-71 239.6 8.4 4.4 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 MOZ_SAS PF01853.13 OAJ13843.1 - 1.7e-82 275.2 0.1 2.5e-82 274.7 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 OAJ13843.1 - 3e-19 68.4 0.1 1.2e-18 66.5 0.1 2.1 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain RXT2_N PF08595.6 OAJ13843.1 - 8.4 6.1 13.0 0.93 9.2 3.3 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal Pkinase PF00069.20 OAJ13845.1 - 8.2e-65 218.5 0.0 3.8e-64 216.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ13845.1 - 5e-34 117.5 0.0 1.1e-33 116.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 OAJ13845.1 - 1.5e-28 98.3 15.1 1.3e-17 63.2 5.6 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 OAJ13845.1 - 8.1e-21 73.5 22.7 3.6e-11 42.6 6.4 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 OAJ13845.1 - 1.6e-08 34.8 2.3 6.3e-08 33.0 1.6 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 OAJ13845.1 - 0.0032 16.4 0.0 0.007 15.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Uds1 PF15456.1 OAJ13845.1 - 0.19 11.7 7.3 0.14 12.1 1.9 2.4 2 0 0 2 2 2 0 Up-regulated During Septation DUF2937 PF11157.3 OAJ13845.1 - 0.3 10.4 7.7 1.1 8.5 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) FYVE_2 PF02318.11 OAJ13845.1 - 4.9 7.0 17.3 14 5.6 4.8 2.9 2 1 1 3 3 3 0 FYVE-type zinc finger Malate_synthase PF01274.17 OAJ13859.1 - 8.2e-203 674.1 0.0 9.3e-203 673.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase WD40 PF00400.27 OAJ13875.1 - 2.4e-13 49.3 20.0 2.8e-05 23.8 0.1 6.3 5 1 0 5 5 5 3 WD domain, G-beta repeat RWD PF05773.17 OAJ13875.1 - 0.01 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 RWD domain Zn_clus PF00172.13 OAJ13878.1 - 6.6e-05 22.7 6.3 0.00011 22.0 4.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EMP24_GP25L PF01105.19 OAJ13879.1 - 7.1e-43 146.4 0.0 9.4e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ribosomal_S18 PF01084.15 OAJ13880.1 - 1e-17 63.7 0.0 1.7e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 SNARE PF05739.14 OAJ13881.1 - 1e-10 41.1 2.1 1e-10 41.1 1.4 2.0 2 0 0 2 2 2 1 SNARE domain FliJ PF02050.11 OAJ13881.1 - 0.052 13.5 2.9 0.19 11.7 0.7 2.4 3 0 0 3 3 3 0 Flagellar FliJ protein YjcZ PF13990.1 OAJ13881.1 - 0.084 11.9 2.9 0.13 11.4 0.6 1.9 2 0 0 2 2 2 0 YjcZ-like protein SlyX PF04102.7 OAJ13881.1 - 3.2 8.1 8.8 1.8 8.9 2.0 3.4 3 2 0 3 3 3 0 SlyX CRAL_TRIO PF00650.15 OAJ13897.1 - 7e-30 103.6 0.0 9.3e-30 103.2 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 OAJ13897.1 - 1.9e-09 37.6 0.0 2.6e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain SSF PF00474.12 OAJ13898.1 - 9.2e-21 73.9 27.4 1.7e-20 73.0 19.0 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DUF1090 PF06476.7 OAJ13899.1 - 0.005 16.4 1.8 0.012 15.2 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1090) PapD-like PF14874.1 OAJ13899.1 - 0.014 15.3 0.0 26 4.8 0.0 3.6 4 0 0 4 4 4 0 Flagellar-associated PapD-like FAM101 PF15068.1 OAJ13901.1 - 0.014 14.8 1.4 0.014 14.8 0.9 2.0 1 1 0 2 2 2 0 FAM101 family YscJ_FliF_C PF08345.6 OAJ13901.1 - 1 9.3 6.9 0.69 9.8 2.1 2.4 2 0 0 2 2 2 0 Flagellar M-ring protein C-terminal Vps51 PF08700.6 OAJ13902.1 - 4.5e-16 58.4 0.4 1.3e-15 56.9 0.3 1.8 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 OAJ13902.1 - 1.5e-06 28.1 0.5 3.8e-06 26.7 0.3 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Mpp10 PF04006.7 OAJ13914.1 - 2.2e-67 227.7 0.1 2.2e-67 227.7 0.0 1.3 2 0 0 2 2 2 1 Mpp10 protein Pap_E4 PF02711.9 OAJ13914.1 - 1.6 9.5 11.0 5.2 7.9 7.6 1.8 1 0 0 1 1 1 0 E4 protein GrpE PF01025.14 OAJ13915.1 - 0.056 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 GrpE Phage_integrase PF00589.17 OAJ13916.1 - 2e-06 27.5 0.1 7.9e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Phage integrase family RVT_3 PF13456.1 OAJ13916.1 - 0.022 14.5 0.1 0.063 13.0 0.1 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like Phospho_p8 PF10195.4 OAJ13916.1 - 0.034 14.0 0.4 0.093 12.6 0.3 1.7 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 Peptidase_C1_2 PF03051.10 OAJ13917.1 - 2e-134 448.4 0.0 5.4e-133 443.7 0.0 2.0 1 1 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 OAJ13917.1 - 6.1e-06 26.2 0.0 0.00056 19.8 0.1 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Hydantoinase_B PF02538.9 OAJ13933.1 - 1e-183 611.4 0.0 3.8e-182 606.1 0.0 2.0 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase PPR_3 PF13812.1 OAJ13935.1 - 0.0017 18.4 0.6 0.39 11.1 0.0 4.6 4 0 0 4 4 4 1 Pentatricopeptide repeat domain SseC PF04888.7 OAJ13953.1 - 0.0045 16.3 56.4 0.0079 15.5 39.1 1.4 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Unstab_antitox PF09720.5 OAJ13953.1 - 0.01 15.4 2.1 0.016 14.8 0.3 2.2 2 0 0 2 2 2 0 Putative addiction module component DUF1510 PF07423.6 OAJ13954.1 - 1.5 8.1 27.6 0.44 9.8 4.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) Hira PF07569.6 OAJ13954.1 - 1.8 7.7 8.7 3.3 6.8 6.0 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split G-7-MTase PF12803.2 OAJ13954.1 - 3.2 6.7 7.0 6.7 5.7 4.9 1.4 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) SAPS PF04499.10 OAJ13954.1 - 3.8 6.0 11.3 2.6 6.5 3.4 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Herpes_UL87 PF03043.9 OAJ13954.1 - 7.8 4.7 10.1 13 4.0 7.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF4218 PF13960.1 OAJ13956.1 - 7.4e-06 25.4 0.2 1.5e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) AAA_5 PF07728.9 OAJ13957.1 - 1.1e-26 93.2 0.0 2.5e-26 92.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) VWA_2 PF13519.1 OAJ13957.1 - 1.4e-06 28.5 0.2 3.3e-06 27.3 0.2 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_22 PF13401.1 OAJ13957.1 - 0.0013 18.8 0.0 0.0058 16.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ13957.1 - 0.0026 17.7 0.9 1.2 9.1 0.0 3.7 3 1 1 4 4 4 1 AAA ATPase domain HI0933_like PF03486.9 OAJ13957.1 - 0.047 12.1 2.1 0.078 11.4 1.4 1.3 1 0 0 1 1 1 0 HI0933-like protein COMP PF11598.3 OAJ13957.1 - 1.2 9.2 4.8 12 6.0 0.6 3.1 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Asp PF00026.18 OAJ13958.1 - 1e-17 64.3 0.0 1.5e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SURF6 PF04935.7 OAJ13975.1 - 1.5e-32 112.6 41.0 1.5e-32 112.6 28.4 3.4 2 2 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 OAJ13975.1 - 1.2e-09 38.0 11.1 1.2e-09 38.0 7.7 5.7 3 2 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 Ceramidase_alk PF04734.8 OAJ13976.1 - 3.6e-207 689.4 0.0 6e-206 685.3 0.0 2.3 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Beta-lactamase PF00144.19 OAJ13977.1 - 1.3e-36 126.3 0.0 1.7e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase WD40 PF00400.27 OAJ13978.1 - 1.9e-82 268.4 25.5 9.5e-13 47.4 0.0 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 OAJ13978.1 - 1e-05 25.4 0.1 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 OAJ13978.1 - 4.2e-05 23.3 0.0 0.0017 18.1 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 OAJ13978.1 - 0.0012 17.0 6.3 4.7 5.2 0.1 4.7 3 2 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAJ13978.1 - 0.0018 17.1 3.6 0.18 10.5 0.1 4.1 3 2 1 4 4 4 1 Nup133 N terminal like Proteasome_A_N PF10584.4 OAJ13978.1 - 0.0018 17.5 1.8 0.2 10.9 0.1 3.0 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Nbas_N PF15492.1 OAJ13978.1 - 0.014 14.4 0.9 0.95 8.5 0.0 2.6 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 OAJ13978.1 - 0.2 9.4 0.1 0.38 8.4 0.0 1.4 1 0 0 1 1 1 0 IKI3 family GreA_GreB_N PF03449.10 OAJ13978.1 - 0.33 11.0 3.7 0.99 9.5 2.6 1.7 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal HMG_box_2 PF09011.5 OAJ13981.1 - 0.032 14.5 0.1 0.12 12.7 0.1 2.0 1 0 0 1 1 1 0 HMG-box domain Pyr_redox_3 PF13738.1 OAJ13982.1 - 1.1e-24 87.6 0.0 1.6e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ13982.1 - 8.1e-05 22.5 0.0 0.00092 19.1 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ13982.1 - 9.1e-05 21.5 0.0 0.00017 20.6 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAJ13982.1 - 0.0067 16.2 0.5 0.32 10.7 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 OAJ13982.1 - 0.016 14.1 0.3 0.029 13.2 0.2 1.3 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 OAJ13982.1 - 0.089 11.8 0.3 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 OAJ13982.1 - 0.2 10.0 3.5 0.6 8.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Trypan_PARP PF05887.6 OAJ13997.1 - 2.4 7.9 7.4 2.7 7.7 5.1 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DARPP-32 PF05395.7 OAJ13997.1 - 4.8 7.3 11.4 0.92 9.6 5.4 1.6 1 1 1 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 PHD PF00628.24 OAJ13998.1 - 0.004 16.8 9.3 0.004 16.8 6.5 1.7 2 0 0 2 2 2 1 PHD-finger Nbl1_Borealin_N PF10444.4 OAJ13999.1 - 0.0029 16.9 0.6 1 8.7 0.1 2.5 2 0 0 2 2 2 2 Nbl1 / Borealin N terminal Myb_DNA-bind_3 PF12776.2 OAJ14000.1 - 0.0035 17.9 0.0 0.0044 17.6 0.0 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain NinB PF05772.7 OAJ14000.1 - 0.022 14.4 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 NinB protein Myb_DNA-bind_4 PF13837.1 OAJ14000.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain RVT_1 PF00078.22 OAJ14001.1 - 1.4e-16 60.5 0.0 2.6e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ14001.1 - 1e-11 44.9 0.0 2.9e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ14001.1 - 0.00012 22.5 0.0 0.0003 21.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ14001.1 - 0.018 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ14001.1 - 0.039 13.7 0.0 0.13 12.0 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Abhydrolase_6 PF12697.2 OAJ14014.1 - 8.2e-27 94.5 0.0 1.2e-26 93.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ14014.1 - 8.3e-21 74.5 0.0 4.8e-18 65.5 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ14014.1 - 1e-08 35.0 0.1 3.3e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAJ14014.1 - 0.00055 19.4 0.0 0.00055 19.4 0.0 2.0 2 1 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.11 OAJ14014.1 - 0.0019 17.6 0.1 0.32 10.4 0.0 2.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 OAJ14014.1 - 0.0033 16.6 0.0 0.099 11.8 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 OAJ14014.1 - 0.0056 15.9 0.0 2.5 7.3 0.0 2.8 2 1 0 2 2 2 2 Dienelactone hydrolase family Esterase_phd PF10503.4 OAJ14014.1 - 0.02 14.1 1.7 0.78 8.9 0.0 2.9 3 0 0 3 3 3 0 Esterase PHB depolymerase PGAP1 PF07819.8 OAJ14014.1 - 0.11 12.0 0.0 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein SR-25 PF10500.4 OAJ14014.1 - 8 5.8 14.7 5.2 6.4 1.5 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Retrotrans_gag PF03732.12 OAJ14015.1 - 1e-15 57.5 0.6 1.5e-15 57.0 0.4 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAJ14015.1 - 8.8e-05 22.2 1.5 0.00016 21.4 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 OAJ14015.1 - 0.15 11.7 3.4 0.29 10.8 2.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Lipocalin_2 PF08212.7 OAJ14016.1 - 1.1e-07 31.7 0.0 3e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Lipocalin-like domain MORN_2 PF07661.8 OAJ14016.1 - 0.15 12.1 0.1 0.42 10.7 0.0 1.8 1 0 0 1 1 1 0 MORN repeat variant Lipocalin_2 PF08212.7 OAJ14017.1 - 1.3e-15 57.4 0.0 1.8e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain BP28CT PF08146.7 OAJ14018.1 - 1.2e-35 122.5 0.6 4.9e-35 120.5 0.4 2.2 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 OAJ14018.1 - 3.6e-07 30.1 2.0 3.6e-07 30.1 1.4 5.4 6 0 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 CLASP_N PF12348.3 OAJ14018.1 - 0.056 12.7 6.1 2.7 7.2 0.2 3.4 3 0 0 3 3 3 0 CLASP N terminal HEAT PF02985.17 OAJ14018.1 - 0.24 11.5 4.4 13 6.1 0.0 5.6 5 0 0 5 5 5 0 HEAT repeat Leo1 PF04004.8 OAJ14019.1 - 1.2e-43 148.8 1.1 2.6e-43 147.7 0.0 2.2 2 0 0 2 2 2 1 Leo1-like protein DUF3473 PF11959.3 OAJ14019.1 - 0.2 11.0 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) Ipi1_N PF12333.3 OAJ14035.1 - 2.7e-10 40.1 0.5 4.8e-09 36.1 0.1 3.0 1 1 1 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation CENP-B_dimeris PF09026.5 OAJ14035.1 - 0.0018 18.4 1.2 0.0039 17.4 0.8 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain PBP1_TM PF14812.1 OAJ14035.1 - 0.03 14.6 1.7 0.071 13.4 1.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BTV_NS2 PF04514.7 OAJ14035.1 - 0.16 10.7 0.5 0.3 9.9 0.3 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FLO_LFY PF01698.11 OAJ14035.1 - 0.21 10.3 0.1 0.48 9.2 0.1 1.6 1 0 0 1 1 1 0 Floricaula / Leafy protein Nucleoplasmin PF03066.10 OAJ14035.1 - 1.5 8.3 6.5 3 7.3 4.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin Acetyltransf_1 PF00583.19 OAJ14036.1 - 1.5e-14 53.7 0.0 2.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAJ14036.1 - 6.6e-10 39.1 0.0 9.9e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 OAJ14036.1 - 1.5e-07 31.4 0.0 2.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ14036.1 - 8.7e-07 28.6 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 OAJ14036.1 - 6e-06 26.3 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 OAJ14036.1 - 6.8e-06 26.3 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAJ14036.1 - 2.2e-05 24.3 0.0 4.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAJ14036.1 - 0.034 14.0 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 OAJ14036.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CtaG_Cox11 PF04442.9 OAJ14037.1 - 6.9e-52 175.2 0.0 1.3e-51 174.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Sec3_C PF09763.4 OAJ14038.1 - 7.7e-89 298.6 0.0 6.8e-88 295.5 0.0 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 OAJ14038.1 - 1.1e-18 66.8 0.0 2.1e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 OAJ14038.1 - 0.036 12.5 0.2 0.056 11.9 0.2 1.2 1 0 0 1 1 1 0 Vps52 / Sac2 family Retrotrans_gag PF03732.12 OAJ14054.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein AAA PF00004.24 OAJ14055.1 - 8.6e-10 38.9 0.1 9.3e-09 35.5 0.0 2.0 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ14055.1 - 2.6e-06 27.5 0.0 3.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ14055.1 - 9.6e-06 25.5 0.0 1.3e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ14055.1 - 0.00028 20.5 0.3 0.0005 19.7 0.2 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 OAJ14055.1 - 0.00031 20.7 0.0 0.00039 20.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 OAJ14055.1 - 0.00038 20.2 0.0 0.00087 19.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 OAJ14055.1 - 0.0012 18.2 0.3 0.002 17.5 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 OAJ14055.1 - 0.0028 17.6 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ14055.1 - 0.0041 17.9 0.0 0.0055 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAJ14055.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.1 OAJ14055.1 - 0.017 14.7 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 OAJ14055.1 - 0.029 13.9 0.1 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAJ14055.1 - 0.072 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 OAJ14055.1 - 0.084 12.4 0.1 0.17 11.4 0.0 1.4 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 OAJ14055.1 - 0.095 11.6 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 RNA_helicase PF00910.17 OAJ14055.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.6 1 1 1 2 2 2 0 RNA helicase ResIII PF04851.10 OAJ14055.1 - 0.17 11.7 0.3 0.62 9.8 0.2 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Trypan_PARP PF05887.6 OAJ14055.1 - 0.34 10.7 6.1 0.56 10.0 4.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.8 OAJ14055.1 - 8.3 4.6 7.9 11 4.2 5.5 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein RVT_1 PF00078.22 OAJ14056.1 - 3.4e-18 65.7 0.0 6e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ14056.1 - 1.7e-15 57.1 0.0 3.1e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Peptidase_C48 PF02902.14 OAJ14058.1 - 0.031 13.9 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain Telomerase_RBD PF12009.3 OAJ14074.1 - 1e-35 122.6 0.0 2.1e-35 121.6 0.0 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 OAJ14074.1 - 1.2e-12 47.6 0.0 5.3e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_A_exo1 PF01612.15 OAJ14075.1 - 1e-14 54.3 0.0 2.2e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease SR-25 PF10500.4 OAJ14075.1 - 2.2 7.6 22.7 0.016 14.6 7.5 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Zn_clus PF00172.13 OAJ14076.1 - 5e-07 29.5 11.1 9.6e-07 28.6 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRP19 PF01922.12 OAJ14077.1 - 5.8e-18 65.2 0.3 1.2e-17 64.2 0.0 1.6 2 0 0 2 2 2 1 SRP19 protein Sec10 PF07393.6 OAJ14078.1 - 1.7e-82 277.7 0.0 4e-78 263.3 0.0 2.1 2 0 0 2 2 2 2 Exocyst complex component Sec10 F-box-like PF12937.2 OAJ14078.1 - 0.0092 15.6 0.3 0.034 13.8 0.2 2.0 1 0 0 1 1 1 1 F-box-like tRNA-synt_1b PF00579.20 OAJ14079.1 - 1e-56 192.2 0.0 9.3e-56 189.0 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 OAJ14079.1 - 0.00093 18.5 0.2 0.0023 17.3 0.1 1.6 1 0 0 1 1 1 1 S4 domain PhoD PF09423.5 OAJ14095.1 - 3e-138 461.2 8.3 3.5e-138 460.9 5.8 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase HNH_2 PF13391.1 OAJ14095.1 - 0.042 13.6 0.0 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease Glycos_transf_1 PF00534.15 OAJ14096.1 - 1.7e-13 50.3 0.0 9.7e-13 47.8 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 OAJ14096.1 - 6.5e-06 26.3 0.0 5.9e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 OAJ14096.1 - 0.059 13.5 0.6 0.16 12.1 0.4 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 OAJ14096.1 - 0.086 13.1 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 Fork_head PF00250.13 OAJ14097.1 - 8.6e-30 102.6 0.0 1.7e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Fork head domain Mito_carr PF00153.22 OAJ14098.1 - 1.2e-58 194.8 20.8 7.5e-23 80.0 0.0 5.0 4 1 0 4 4 4 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 OAJ14098.1 - 2.8e-05 23.0 0.2 0.00034 19.7 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 OAJ14098.1 - 0.00037 20.1 0.1 0.004 16.9 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 OAJ14098.1 - 0.00049 19.3 0.4 0.0015 17.7 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 OAJ14098.1 - 0.00071 19.6 0.5 0.0019 18.2 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair FCP1_C PF09309.5 OAJ14099.1 - 0.022 14.1 0.2 0.022 14.1 0.2 1.9 2 0 0 2 2 2 0 FCP1, C-terminal DUF4477 PF14780.1 OAJ14099.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Abhydrolase_6 PF12697.2 OAJ14100.1 - 1.1e-25 90.9 0.0 1.4e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ14100.1 - 5.4e-17 62.1 0.0 9.7e-11 41.6 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ14100.1 - 2.6e-10 40.2 0.0 3.8e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAJ14100.1 - 0.001 18.5 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 OAJ14100.1 - 0.012 15.0 0.1 0.69 9.3 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 OAJ14100.1 - 0.045 13.3 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 OAJ14100.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Tubulin PF00091.20 OAJ14101.1 - 1.3e-62 211.3 0.0 2e-61 207.5 0.0 2.1 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 OAJ14101.1 - 8.4e-45 151.8 0.0 1.3e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 OAJ14101.1 - 0.00042 19.8 0.0 0.00084 18.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 OAJ14101.1 - 0.042 13.4 0.1 0.72 9.4 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) FAM72 PF14976.1 OAJ14116.1 - 3.8e-21 75.5 0.2 9.6e-21 74.1 0.1 1.6 2 0 0 2 2 2 1 FAM72 protein GST_N_3 PF13417.1 OAJ14117.1 - 3.8e-16 59.0 0.0 7.7e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAJ14117.1 - 1.2e-13 50.9 0.0 2.7e-13 49.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ14117.1 - 8.7e-12 44.8 0.0 3.7e-11 42.8 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ14117.1 - 9e-10 38.4 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ14117.1 - 9.5e-09 35.6 0.1 1.6e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ14117.1 - 1.1e-05 25.2 0.0 2.8e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HATPase_c PF02518.21 OAJ14134.1 - 2.8e-31 107.5 0.1 2.8e-28 97.8 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAJ14134.1 - 5.1e-24 84.4 0.3 1.2e-23 83.2 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.5 OAJ14134.1 - 1.8e-23 82.6 2.3 2.4e-11 43.6 0.0 6.2 5 1 0 5 5 5 3 PAS fold HisKA PF00512.20 OAJ14134.1 - 2.3e-20 72.3 0.1 6e-20 71.0 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 OAJ14134.1 - 2.9e-17 62.9 0.0 1.8e-10 41.1 0.0 4.6 4 1 0 4 4 4 3 PAS domain PAS PF00989.19 OAJ14134.1 - 1.4e-13 50.6 0.2 0.0056 16.4 0.0 5.7 6 1 0 6 6 6 3 PAS fold PAS_3 PF08447.6 OAJ14134.1 - 1.6e-12 47.3 0.2 4.8e-12 45.8 0.1 1.9 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 OAJ14134.1 - 0.00094 18.9 0.0 4.5 7.2 0.0 4.2 4 0 0 4 4 4 1 PAS domain HATPase_c_3 PF13589.1 OAJ14134.1 - 0.0035 16.9 0.2 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.1 OAJ14134.1 - 0.14 12.4 0.0 96 3.3 0.0 4.0 4 0 0 4 4 4 0 PAS domain UBN2 PF14223.1 OAJ14136.1 - 1.2e-09 37.9 0.0 2.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAJ14136.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ14136.1 - 0.12 12.3 3.6 0.21 11.5 2.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Shugoshin_N PF07558.6 OAJ14139.1 - 0.023 14.4 0.4 0.023 14.4 0.3 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region MamL-1 PF09596.5 OAJ14139.1 - 0.025 14.3 3.8 0.073 12.8 2.6 1.8 1 0 0 1 1 1 0 MamL-1 domain Glyco_transf_28 PF03033.15 OAJ14139.1 - 0.052 13.3 0.1 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain DUF972 PF06156.8 OAJ14139.1 - 0.35 11.2 17.5 2.6 8.4 0.0 4.7 3 1 1 4 4 4 0 Protein of unknown function (DUF972) DUF904 PF06005.7 OAJ14139.1 - 0.62 10.3 25.9 0.16 12.3 0.5 4.7 3 1 0 3 3 3 0 Protein of unknown function (DUF904) Tom37_C PF11801.3 OAJ14140.1 - 0.05 13.4 2.3 0.78 9.5 1.6 2.1 2 0 0 2 2 2 0 Tom37 C-terminal domain DUF4355 PF14265.1 OAJ14140.1 - 0.56 10.1 9.7 1.4 8.9 6.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Sulfate_transp PF00916.15 OAJ14178.1 - 3.8e-07 29.3 0.1 6.5e-07 28.6 0.1 1.3 1 0 0 1 1 1 1 Sulfate transporter family Ribosomal_L36e PF01158.13 OAJ14179.1 - 3.4e-37 126.3 6.3 4e-37 126.1 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF3140 PF11338.3 OAJ14179.1 - 0.086 12.9 0.5 0.14 12.3 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3140) Asp PF00026.18 OAJ14180.1 - 1.3e-31 109.9 0.1 1.7e-22 80.1 0.0 2.8 2 1 0 2 2 2 2 Eukaryotic aspartyl protease CTP_transf_1 PF01148.15 OAJ14181.1 - 3.6e-67 226.7 26.9 3.5e-66 223.4 18.6 2.0 1 1 0 1 1 1 1 Cytidylyltransferase family LRR19-TM PF15176.1 OAJ14181.1 - 0.086 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain ATP-synt_B PF00430.13 OAJ14181.1 - 0.49 10.1 5.4 1.1 9.0 3.7 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) MULE PF10551.4 OAJ14182.1 - 3.3e-12 46.3 0.1 1.3e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 OAJ14182.1 - 1.7e-08 33.4 2.4 9.3e-08 31.0 0.1 2.2 2 0 0 2 2 2 2 Transposase, Mutator family FAR1 PF03101.10 OAJ14182.1 - 0.013 16.0 1.2 0.027 14.9 0.8 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain A_deamin PF02137.13 OAJ14183.1 - 1.5e-52 179.0 0.0 2e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Complex1_LYR PF05347.10 OAJ14184.1 - 3.9e-08 32.9 0.2 7.3e-08 32.0 0.2 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAJ14184.1 - 1.7e-07 31.3 0.2 3.4e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 OAJ14184.1 - 2.3e-06 27.9 0.0 3.9e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Asparaginase PF00710.15 OAJ14198.1 - 9.1e-126 418.9 0.0 1.2e-125 418.5 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 OAJ14198.1 - 8.1e-12 45.3 0.0 1.6e-11 44.3 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ14198.1 - 3.4e-11 42.3 0.8 2e-05 24.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 OAJ14198.1 - 3.6e-10 40.0 0.2 2.1e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ14198.1 - 7.1e-10 38.1 1.8 2e-05 24.3 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 OAJ14198.1 - 1e-07 31.9 1.1 0.00026 21.1 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) zf-CCHC PF00098.18 OAJ14199.1 - 9e-07 28.5 3.0 2.1e-06 27.3 2.1 1.7 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 OAJ14199.1 - 3.7e-05 23.4 0.0 7.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 OAJ14199.1 - 0.3 10.7 0.9 0.63 9.7 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.9 OAJ14200.1 - 5.3e-86 287.5 0.0 7.3e-86 287.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ14200.1 - 3.3e-23 82.0 0.3 4.7e-22 78.3 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 OAJ14200.1 - 0.0049 16.3 0.5 0.042 13.3 0.3 2.5 1 1 0 1 1 1 1 Integrase core domain Arrestin_N PF00339.24 OAJ14201.1 - 0.0018 18.1 0.0 0.0054 16.5 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Glyco_hydro_cc PF11790.3 OAJ14202.1 - 7.3e-55 185.9 2.1 9.6e-55 185.6 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.8 OAJ14202.1 - 0.088 11.5 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 SNARE_assoc PF09335.6 OAJ14221.1 - 1.1e-16 61.0 4.3 1.1e-16 61.0 3.0 2.7 2 1 1 3 3 3 1 SNARE associated Golgi protein FtsX PF02687.16 OAJ14221.1 - 0.53 10.0 12.4 0.62 9.8 0.2 3.3 2 1 1 3 3 3 0 FtsX-like permease family DUF202 PF02656.10 OAJ14221.1 - 4.2 7.6 8.2 2.9 8.1 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Ctr PF04145.10 OAJ14221.1 - 9.1 6.3 7.9 0.57 10.2 0.8 2.4 2 1 0 2 2 2 0 Ctr copper transporter family Arrestin_N PF00339.24 OAJ14222.1 - 0.0036 17.1 0.0 0.0086 15.8 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Ribosomal_L13 PF00572.13 OAJ14223.1 - 1.8e-48 163.7 1.0 2.1e-48 163.5 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 SH3_9 PF14604.1 OAJ14224.1 - 1.5e-22 78.8 0.5 1.8e-13 49.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 OAJ14224.1 - 1.3e-19 69.3 0.0 2.5e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 OAJ14224.1 - 1.7e-15 56.2 0.1 4.4e-09 35.6 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 OAJ14224.1 - 1.3e-13 50.9 0.1 1.4e-12 47.5 0.0 2.8 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.17 OAJ14224.1 - 1.4e-11 43.9 5.2 2.2e-11 43.3 3.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.6 OAJ14224.1 - 0.0012 19.0 1.3 0.0018 18.3 0.2 1.9 2 0 0 2 2 2 1 Bacterial SH3 domain Prominin PF05478.6 OAJ14224.1 - 1.4 6.3 3.6 4.9 4.5 2.5 1.8 1 1 0 1 1 1 0 Prominin PDGLE PF13190.1 OAJ14225.1 - 0.024 14.3 1.3 0.067 12.8 0.4 2.2 2 0 0 2 2 2 0 PDGLE domain Daxx PF03344.10 OAJ14225.1 - 0.86 8.0 10.2 1.3 7.4 7.1 1.2 1 0 0 1 1 1 0 Daxx Family Methyltransf_17 PF12692.2 OAJ14227.1 - 0.00031 20.4 0.4 0.0022 17.7 0.1 2.3 2 1 0 2 2 2 1 S-adenosyl-L-methionine methyltransferase Baculo_PEP_C PF04513.7 OAJ14227.1 - 0.044 13.5 0.4 5.9 6.7 0.0 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PadR PF03551.9 OAJ14227.1 - 0.12 12.1 0.0 0.51 10.1 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family ATE_N PF04376.8 OAJ14228.1 - 0.05 13.4 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, N terminus Ndc1_Nup PF09531.5 OAJ14246.1 - 1.5e-09 36.8 17.1 1.4e-08 33.6 0.0 4.9 4 2 1 5 5 5 3 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.11 OAJ14250.1 - 3.1e-43 147.8 58.0 9.2e-43 146.2 35.5 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAJ14250.1 - 7e-18 64.1 13.4 7e-18 64.1 9.3 1.9 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 OAJ14250.1 - 3.9e-15 55.3 5.0 3.9e-15 55.3 3.5 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter PDR_CDR PF06422.7 OAJ14251.1 - 0.018 14.6 0.1 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 CDR ABC transporter SurE PF01975.12 OAJ14252.1 - 2.2e-14 53.2 2.3 2.8e-14 52.8 0.0 1.9 1 1 1 2 2 2 1 Survival protein SurE SNase PF00565.12 OAJ14272.1 - 4.6e-21 75.0 2.4 2e-19 69.8 0.7 2.7 2 1 0 2 2 2 1 Staphylococcal nuclease homologue DUF3526 PF12040.3 OAJ14272.1 - 0.044 13.9 0.2 0.37 10.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3526) CBM_21 PF03370.8 OAJ14273.1 - 3e-30 104.4 0.1 5.2e-30 103.7 0.1 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit 2Fe-2S_thioredx PF01257.14 OAJ14274.1 - 4.5e-59 198.1 0.0 5.8e-59 197.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin HLH PF00010.21 OAJ14289.1 - 4.4e-06 26.3 0.9 1.1e-05 25.0 0.6 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nop14 PF04147.7 OAJ14289.1 - 0.01 13.8 17.2 0.13 10.2 4.5 2.1 2 0 0 2 2 2 0 Nop14-like family ELL PF10390.4 OAJ14289.1 - 0.018 14.2 0.3 0.018 14.2 0.2 3.0 3 1 0 3 3 3 0 RNA polymerase II elongation factor ELL Sigma70_ner PF04546.8 OAJ14289.1 - 0.4 10.2 14.0 0.59 9.7 1.1 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region SDA1 PF05285.7 OAJ14289.1 - 2.2 7.4 24.9 0.2 10.9 3.5 2.9 3 0 0 3 3 3 0 SDA1 RRM_1 PF00076.17 OAJ14290.1 - 4.2e-23 80.7 0.0 2.6e-11 42.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ14290.1 - 1.9e-18 66.1 0.0 6.1e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 OAJ14290.1 - 3e-17 61.0 0.0 0.00029 20.1 0.0 5.7 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_5 PF13893.1 OAJ14290.1 - 2.8e-13 49.4 0.0 1.3e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_21 PF13276.1 OAJ14290.1 - 0.31 11.0 0.1 0.75 9.8 0.1 1.5 1 0 0 1 1 1 0 HTH-like domain Nab6_mRNP_bdg PF10567.4 OAJ14290.1 - 0.52 9.2 0.0 1.2 8.0 0.0 1.5 1 0 0 1 1 1 0 RNA-recognition motif LIM_bind PF01803.11 OAJ14290.1 - 6.9 5.7 7.8 15 4.5 5.4 1.5 1 0 0 1 1 1 0 LIM-domain binding protein tRNA-synt_1g PF09334.6 OAJ14291.1 - 1.8e-91 306.7 0.4 5e-75 252.5 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 OAJ14291.1 - 7.7e-13 47.3 0.0 1.2e-05 23.6 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 OAJ14291.1 - 4.5e-06 25.9 0.4 0.02 13.9 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Acyl-CoA_dh_C PF12806.2 OAJ14291.1 - 0.11 12.3 1.1 0.27 11.0 0.7 1.6 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like Pkinase PF00069.20 OAJ14317.1 - 2.1e-66 223.7 0.0 4.2e-66 222.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ14317.1 - 1.5e-34 119.2 0.0 1.4e-33 116.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ14317.1 - 1.3e-06 27.6 0.0 2.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.14 OAJ14317.1 - 0.00037 19.8 0.0 0.00061 19.1 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 RIO1 PF01163.17 OAJ14317.1 - 0.032 13.5 0.1 0.08 12.2 0.0 1.6 1 0 0 1 1 1 0 RIO1 family DDE_1 PF03184.14 OAJ14318.1 - 9.1e-33 113.2 0.0 1.9e-32 112.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAJ14318.1 - 6.6e-09 35.4 0.0 3.3e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Retrotrans_gag PF03732.12 OAJ14318.1 - 0.084 12.9 1.8 0.35 10.9 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein Mg_trans_NIPA PF05653.9 OAJ14319.1 - 3.4e-61 206.8 0.0 3.2e-56 190.4 0.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 OAJ14319.1 - 5.7e-08 32.9 8.7 2.4e-05 24.4 0.1 2.7 2 1 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 OAJ14319.1 - 0.0004 20.4 0.6 0.0004 20.4 0.4 3.1 3 1 0 3 3 3 1 EamA-like transporter family 7TMR-DISM_7TM PF07695.6 OAJ14319.1 - 0.023 14.3 4.3 0.056 13.1 3.0 1.6 1 0 0 1 1 1 0 7TM diverse intracellular signalling AAA_27 PF13514.1 OAJ14320.1 - 0.0026 15.5 0.0 0.0032 15.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain Cyclin_N PF00134.18 OAJ14321.1 - 3.6e-36 123.5 0.1 8.5e-36 122.3 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ14321.1 - 7.2e-11 42.0 0.5 2.1e-10 40.5 0.4 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Thymidylat_synt PF00303.14 OAJ14322.1 - 9.4e-27 93.6 0.0 1e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Sedlin_N PF04628.8 OAJ14340.1 - 7.5e-29 100.2 0.0 1.1e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Chorion_2 PF03964.10 OAJ14340.1 - 4.2 7.9 11.0 1.7 9.2 1.4 2.5 2 0 0 2 2 2 0 Chorion family 2 Aconitase PF00330.15 OAJ14341.1 - 4.4e-73 246.3 0.0 6.4e-48 163.3 0.0 3.0 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAJ14341.1 - 2.2e-20 73.1 0.0 4.7e-20 72.0 0.0 1.6 1 1 0 1 1 1 1 Aconitase C-terminal domain SKG6 PF08693.5 OAJ14342.1 - 1.2e-10 40.5 1.1 1.2e-10 40.5 0.8 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 OAJ14342.1 - 2.4e-05 23.9 0.1 4.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF1183 PF06682.7 OAJ14342.1 - 0.0012 18.5 4.6 0.0012 18.5 3.2 4.3 4 0 0 4 4 4 1 Protein of unknown function (DUF1183) TMEM154 PF15102.1 OAJ14342.1 - 0.0049 16.5 0.2 0.012 15.3 0.2 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF912 PF06024.7 OAJ14342.1 - 0.0075 16.2 0.4 0.025 14.6 0.0 2.0 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Adeno_E3_CR2 PF02439.10 OAJ14342.1 - 0.0097 15.4 1.1 0.025 14.1 0.7 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 CENP-B_dimeris PF09026.5 OAJ14342.1 - 0.033 14.4 0.9 0.09 13.0 0.6 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2627 PF11118.3 OAJ14342.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Rifin_STEVOR PF02009.11 OAJ14342.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family ELO PF01151.13 OAJ14343.1 - 4.6e-55 186.6 10.5 5.4e-55 186.4 7.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Zn_clus PF00172.13 OAJ14346.1 - 9.9e-05 22.1 15.3 0.00019 21.2 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PI3_PI4_kinase PF00454.22 OAJ14361.1 - 3.2e-51 174.0 0.0 6.2e-51 173.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 OAJ14361.1 - 1.1e-31 110.1 0.0 2.1e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.8 OAJ14361.1 - 1.3e-19 70.0 0.0 6.3e-19 67.9 0.0 2.3 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 OAJ14361.1 - 2.9e-08 32.9 0.0 7e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.3 OAJ14361.1 - 0.0039 17.1 0.0 0.016 15.1 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) HEAT_EZ PF13513.1 OAJ14361.1 - 0.19 12.2 8.5 1.8 9.1 1.5 4.5 4 0 0 4 4 4 0 HEAT-like repeat DRMBL PF07522.9 OAJ14362.1 - 7.3e-27 93.5 0.0 1.5e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 OAJ14362.1 - 2.5e-06 27.1 0.0 1.1e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain zf-C2HC_2 PF13913.1 OAJ14362.1 - 0.00093 18.7 4.1 0.0017 17.9 0.6 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type Lactamase_B PF00753.22 OAJ14362.1 - 0.0082 15.8 0.2 0.02 14.5 0.1 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily CcdB PF01845.12 OAJ14362.1 - 0.23 11.3 0.0 0.43 10.5 0.0 1.4 1 0 0 1 1 1 0 CcdB protein XFP_N PF09364.5 OAJ14364.1 - 6.6e-124 413.2 0.4 3.2e-103 345.2 0.0 2.1 2 0 0 2 2 2 2 XFP N-terminal domain XFP_C PF09363.5 OAJ14364.1 - 4e-53 179.8 0.0 3.4e-39 134.3 0.0 2.3 2 0 0 2 2 2 2 XFP C-terminal domain XFP PF03894.10 OAJ14364.1 - 3.7e-49 166.7 0.0 7.5e-49 165.7 0.0 1.5 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.16 OAJ14364.1 - 0.0094 15.5 0.3 0.022 14.3 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain RNase_P_pop3 PF08228.6 OAJ14385.1 - 0.0023 17.8 0.0 2.3 8.0 0.0 2.5 2 0 0 2 2 2 2 RNase P subunit Pop3 Asp_Glu_race PF01177.17 OAJ14386.1 - 2.6e-24 86.3 0.1 3.1e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase GTP_EFTU PF00009.22 OAJ14387.1 - 5.8e-38 130.2 0.0 9.9e-38 129.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 OAJ14387.1 - 1.4e-37 127.5 0.4 3.5e-37 126.3 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 OAJ14387.1 - 4.1e-12 46.0 0.4 1.4e-11 44.3 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAJ14387.1 - 0.037 13.9 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase OLF PF02191.11 OAJ14390.1 - 0.057 12.6 0.1 0.065 12.4 0.1 1.0 1 0 0 1 1 1 0 Olfactomedin-like domain MFS_1 PF07690.11 OAJ14400.1 - 4.4e-41 140.7 22.2 8.5e-39 133.2 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ14400.1 - 2.5e-12 46.1 6.6 2.5e-12 46.1 4.6 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 OAJ14400.1 - 0.00031 19.0 3.7 0.00051 18.3 2.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF697 PF05128.7 OAJ14400.1 - 0.0086 15.5 1.6 0.69 9.3 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF697) MCM PF00493.18 OAJ14401.1 - 1.1e-135 451.6 0.2 1.1e-135 451.6 0.2 1.5 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 OAJ14401.1 - 6.4e-19 68.6 0.0 2.1e-18 66.9 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 OAJ14401.1 - 8.1e-08 31.6 0.0 7.6e-07 28.4 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 OAJ14401.1 - 0.0013 18.2 0.0 0.0028 17.1 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ14401.1 - 0.0018 17.9 0.0 0.0056 16.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 OAJ14401.1 - 0.0022 17.5 0.0 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SapB_1 PF05184.10 OAJ14401.1 - 0.2 11.5 1.5 1.7 8.5 0.4 2.6 2 0 0 2 2 2 0 Saposin-like type B, region 1 MMR_HSR1 PF01926.18 OAJ14402.1 - 7.2e-17 61.4 0.0 1.1e-14 54.3 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ14402.1 - 4.7e-06 25.9 0.0 5.5e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 OAJ14402.1 - 9.6e-05 21.6 0.0 0.00019 20.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 OAJ14402.1 - 0.0011 18.1 0.0 0.004 16.2 0.0 1.9 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 OAJ14402.1 - 0.073 13.5 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Nop14 PF04147.7 OAJ14402.1 - 0.16 9.8 21.4 0.21 9.4 14.8 1.1 1 0 0 1 1 1 0 Nop14-like family HTH_17 PF12728.2 OAJ14402.1 - 0.17 12.1 0.8 10 6.4 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain Dynamin_N PF00350.18 OAJ14402.1 - 0.22 11.3 7.1 0.09 12.5 0.4 2.9 3 1 1 4 4 4 0 Dynamin family SDA1 PF05285.7 OAJ14402.1 - 0.26 10.5 21.6 0.42 9.8 15.0 1.2 1 0 0 1 1 1 0 SDA1 SAPS PF04499.10 OAJ14402.1 - 0.5 8.9 5.5 0.72 8.4 3.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_pol_3_Rpc31 PF11705.3 OAJ14402.1 - 0.93 9.3 20.9 2.1 8.2 14.5 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 U79_P34 PF03064.11 OAJ14402.1 - 1.1 8.7 8.3 2.1 7.8 5.7 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Spore_coat_CotO PF14153.1 OAJ14402.1 - 1.1 8.6 9.6 0.17 11.2 3.8 1.7 2 0 0 2 2 2 0 Spore coat protein CotO MscS_TM PF12794.2 OAJ14402.1 - 2.9 6.4 3.5 4.5 5.7 2.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Ribosomal_60s PF00428.14 OAJ14402.1 - 4.4 7.7 18.1 13 6.2 12.6 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Daxx PF03344.10 OAJ14402.1 - 4.6 5.6 25.6 6.8 5.0 17.7 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 OAJ14402.1 - 6.1 4.7 16.9 8.5 4.2 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 OAJ14402.1 - 9.1 5.4 15.6 14 4.8 10.8 1.3 1 0 0 1 1 1 0 NOA36 protein AAA PF00004.24 OAJ14403.1 - 1.2e-90 300.5 0.0 3.5e-46 156.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 OAJ14403.1 - 6.2e-14 51.6 0.0 9.3e-07 28.1 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 OAJ14403.1 - 9.1e-12 45.2 0.2 0.0032 17.6 0.0 4.9 3 2 1 4 4 3 3 AAA domain AAA_17 PF13207.1 OAJ14403.1 - 4.3e-11 43.6 0.0 8e-06 26.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.9 OAJ14403.1 - 7.8e-11 42.1 0.0 0.00022 21.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 OAJ14403.1 - 1.4e-10 41.0 0.3 0.0014 18.3 0.1 4.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 OAJ14403.1 - 1.5e-10 41.3 5.9 0.00041 20.3 0.1 4.3 3 1 0 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 OAJ14403.1 - 1.5e-09 37.0 0.0 1.8e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 OAJ14403.1 - 6.3e-09 35.8 0.0 0.0044 16.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.1 OAJ14403.1 - 7.8e-09 35.5 0.0 0.0045 16.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 OAJ14403.1 - 9e-08 31.4 0.0 0.013 14.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 OAJ14403.1 - 1.7e-07 30.8 0.0 0.013 14.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.7 OAJ14403.1 - 4.1e-07 29.8 0.7 0.034 13.8 0.1 3.9 3 1 1 4 4 4 2 NACHT domain Mg_chelatase PF01078.16 OAJ14403.1 - 4.3e-07 29.3 2.3 0.017 14.2 0.0 2.8 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 OAJ14403.1 - 5.1e-07 29.7 0.0 0.019 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 OAJ14403.1 - 5.9e-07 29.6 0.0 0.047 13.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 OAJ14403.1 - 9e-07 28.4 5.7 0.23 10.8 0.1 4.6 2 2 2 4 4 4 2 AAA domain ABC_tran PF00005.22 OAJ14403.1 - 4.2e-06 27.0 0.0 0.076 13.3 0.0 3.0 3 0 0 3 3 2 2 ABC transporter AAA_19 PF13245.1 OAJ14403.1 - 6.6e-06 25.7 9.0 0.013 15.2 0.0 4.4 4 1 0 4 4 3 2 Part of AAA domain AAA_18 PF13238.1 OAJ14403.1 - 3e-05 24.3 0.0 0.2 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 OAJ14403.1 - 3.1e-05 23.5 0.0 0.052 13.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 OAJ14403.1 - 3.3e-05 23.9 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 OAJ14403.1 - 8e-05 22.1 0.2 0.44 10.0 0.0 4.0 5 0 0 5 5 4 1 Sigma-54 interaction domain KaiC PF06745.8 OAJ14403.1 - 8.6e-05 21.7 0.1 1.5 7.8 0.0 3.2 3 0 0 3 3 3 1 KaiC Viral_helicase1 PF01443.13 OAJ14403.1 - 0.00032 20.3 0.0 0.75 9.2 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 OAJ14403.1 - 0.00069 18.5 0.1 0.34 9.7 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain SKI PF01202.17 OAJ14403.1 - 0.0012 18.7 0.0 1.4 8.7 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase PhoH PF02562.11 OAJ14403.1 - 0.0014 17.8 0.2 1 8.5 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein Cytidylate_kin2 PF13189.1 OAJ14403.1 - 0.0023 17.8 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family Arch_ATPase PF01637.13 OAJ14403.1 - 0.0024 17.6 0.0 1.5 8.4 0.0 3.1 2 1 1 3 3 3 1 Archaeal ATPase Parvo_NS1 PF01057.12 OAJ14403.1 - 0.0025 16.7 0.1 1.6 7.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.8 OAJ14403.1 - 0.0029 16.5 0.0 0.03 13.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ResIII PF04851.10 OAJ14403.1 - 0.0035 17.1 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Rad17 PF03215.10 OAJ14403.1 - 0.0046 15.7 0.0 1.1 7.8 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein ATP-synt_ab PF00006.20 OAJ14403.1 - 0.005 16.3 0.0 0.59 9.5 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 OAJ14403.1 - 0.0057 16.2 0.8 3.4 7.3 0.0 2.7 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 Lzipper-MIP1 PF14389.1 OAJ14403.1 - 0.01 15.8 0.3 0.058 13.4 0.1 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 AAA_11 PF13086.1 OAJ14403.1 - 0.012 15.2 0.1 5.8 6.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain AFG1_ATPase PF03969.11 OAJ14403.1 - 0.013 14.3 0.4 1.4 7.6 0.0 2.6 3 0 0 3 3 2 0 AFG1-like ATPase AAA_24 PF13479.1 OAJ14403.1 - 0.022 14.3 0.2 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 OAJ14403.1 - 0.028 14.1 0.0 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 OAJ14403.1 - 0.067 12.6 0.0 9.1 5.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.13 OAJ14403.1 - 0.24 10.9 0.0 4.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein DUF2075 PF09848.4 OAJ14403.1 - 0.25 10.2 0.1 20 4.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TFIIA PF03153.8 OAJ14403.1 - 4.1 7.2 10.4 6.3 6.5 7.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAD-oxidase_C PF02913.14 OAJ14404.1 - 1.3e-58 198.2 0.0 2.2e-58 197.5 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 OAJ14404.1 - 1.5e-33 115.2 1.0 2.8e-33 114.3 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain SMP_2 PF10144.4 OAJ14404.1 - 0.086 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin Relaxase PF03432.9 OAJ14404.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Ilar_coat PF01787.11 OAJ14404.1 - 0.18 11.3 0.6 0.69 9.4 0.0 2.1 2 1 0 2 2 2 0 Ilarvirus coat protein EpuA PF11772.3 OAJ14404.1 - 0.34 10.3 1.8 1.1 8.7 1.3 1.9 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta CHCH PF06747.8 OAJ14405.1 - 3.1e-05 23.7 4.9 3.1e-05 23.7 3.4 2.5 2 1 0 2 2 2 1 CHCH domain Pet191_N PF10203.4 OAJ14405.1 - 0.33 11.0 9.7 0.37 10.8 2.9 2.7 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 DUF3128 PF11326.3 OAJ14405.1 - 1.1 9.4 5.9 0.38 10.9 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) Proteasome PF00227.21 OAJ14406.1 - 1.7e-06 27.4 0.0 0.00012 21.4 0.0 2.1 1 1 0 1 1 1 1 Proteasome subunit Sporozoite_P67 PF05642.6 OAJ14406.1 - 0.13 10.0 0.7 0.13 10.0 0.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 OAJ14406.1 - 0.16 10.4 3.5 0.16 10.4 2.4 1.0 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 OAJ14406.1 - 0.25 9.2 3.8 0.28 9.0 2.7 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 OAJ14406.1 - 2 8.0 8.2 2.6 7.6 5.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region ABC2_membrane PF01061.19 OAJ14422.1 - 2.3e-30 105.3 15.8 4.5e-30 104.3 10.9 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 OAJ14422.1 - 1e-25 90.6 0.1 1.7e-25 89.8 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 OAJ14422.1 - 1.1e-08 35.3 0.1 0.005 16.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAJ14422.1 - 3e-05 23.4 0.3 0.023 14.1 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 OAJ14422.1 - 7.2e-05 22.0 0.0 0.016 14.3 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 OAJ14422.1 - 8.9e-05 22.6 0.2 0.00058 20.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 OAJ14422.1 - 0.00014 21.3 0.9 0.00084 18.8 0.3 2.4 2 1 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ14422.1 - 0.00018 21.5 0.3 0.00047 20.1 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 OAJ14422.1 - 0.0031 16.7 0.1 0.0031 16.7 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 OAJ14422.1 - 0.0087 15.7 0.2 0.024 14.3 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_23 PF13476.1 OAJ14422.1 - 0.011 16.0 0.1 0.017 15.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 OAJ14422.1 - 0.017 14.5 0.1 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 OAJ14422.1 - 0.036 13.9 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 OAJ14422.1 - 0.08 13.7 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 OAJ14422.1 - 0.13 11.1 0.1 0.27 10.0 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 OAJ14422.1 - 0.13 11.9 0.2 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 OAJ14422.1 - 0.15 11.7 0.2 0.33 10.6 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 OAJ14422.1 - 0.78 9.6 2.4 0.61 10.0 0.3 1.8 2 0 0 2 2 1 0 AAA domain FAD_binding_8 PF08022.7 OAJ14423.1 - 4.1e-19 68.4 0.0 8.7e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 OAJ14423.1 - 6.1e-14 52.2 0.1 3.5e-12 46.4 0.0 3.2 2 2 1 3 3 3 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 OAJ14423.1 - 4.9e-09 36.3 9.6 5.9e-09 36.0 5.6 1.9 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 OAJ14423.1 - 0.0022 18.0 0.0 0.0061 16.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain FAD_binding_8 PF08022.7 OAJ14424.1 - 6.2e-19 67.8 0.0 1.2e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 OAJ14424.1 - 3.4e-15 56.2 0.0 6e-14 52.2 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 OAJ14424.1 - 3.3e-09 36.8 6.8 3.4e-09 36.8 3.6 1.8 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 OAJ14424.1 - 0.00073 19.6 0.0 0.028 14.5 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Fungal_trans_2 PF11951.3 OAJ14424.1 - 0.054 12.0 0.0 0.088 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain PAT1 PF09770.4 OAJ14425.1 - 9.8e-159 530.1 19.6 1.2e-157 526.5 13.6 2.4 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 ELYS PF13934.1 OAJ14426.1 - 2.5e-07 30.6 1.0 6.2e-07 29.3 0.7 1.6 1 1 0 1 1 1 1 Nuclear pore complex assembly Polysacc_deac_1 PF01522.16 OAJ14444.1 - 1.7e-17 63.1 0.0 3.3e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 OAJ14444.1 - 0.048 12.5 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Glyco_transf_17 PF04724.8 OAJ14445.1 - 1.7e-94 316.8 0.0 2e-94 316.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 Glycos_transf_1 PF00534.15 OAJ14446.1 - 7.3e-30 103.6 0.1 5.8e-28 97.4 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 OAJ14446.1 - 2.7e-13 50.3 0.0 8.2e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 OAJ14446.1 - 3.3e-12 46.7 0.0 7.8e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 OAJ14446.1 - 1.2e-11 44.6 0.0 2.1e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 OAJ14446.1 - 6.5e-05 23.1 0.4 0.71 10.1 0.0 3.1 3 0 0 3 3 3 2 Glycosyl transferases group 1 E1-E2_ATPase PF00122.15 OAJ14447.1 - 1.4e-58 197.6 0.1 1.4e-58 197.6 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAJ14447.1 - 2.2e-43 147.8 5.5 2.2e-43 147.8 3.8 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ14447.1 - 3.8e-26 92.8 0.1 2.5e-25 90.1 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ14447.1 - 4.1e-19 68.3 0.4 1.1e-18 66.9 0.3 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 OAJ14447.1 - 1.9e-15 57.5 0.0 6.3e-15 55.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAJ14447.1 - 7.3e-10 38.1 0.0 4.8e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 OAJ14447.1 - 9.8e-05 22.0 1.1 0.012 15.2 0.2 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 OAJ14466.1 - 2.1e-47 161.4 0.0 4.9e-47 160.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ14466.1 - 7.7e-33 113.6 0.0 1.3e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 OAJ14466.1 - 0.00033 19.7 0.5 0.0017 17.4 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ14466.1 - 0.0078 15.2 0.0 0.018 13.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like zf-C4H2 PF10146.4 OAJ14466.1 - 0.74 9.7 14.6 1.9 8.4 0.8 2.5 1 1 1 2 2 2 0 Zinc finger-containing protein IncA PF04156.9 OAJ14466.1 - 0.75 9.3 34.2 0.1 12.1 0.5 3.8 1 1 2 4 4 4 0 IncA protein Cast PF10174.4 OAJ14466.1 - 1.6 6.6 32.0 0.99 7.3 7.4 2.2 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone CENP-F_leu_zip PF10473.4 OAJ14466.1 - 5 6.9 29.9 1.4 8.7 0.9 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 OAJ14466.1 - 8.4 5.9 21.7 3.2 7.3 0.5 4.9 4 1 1 5 5 5 0 Septum formation initiator Mnd1 PF03962.10 OAJ14466.1 - 9.8 5.7 19.9 0.98 9.0 4.1 2.9 1 1 1 2 2 2 0 Mnd1 family Stm1_N PF09598.5 OAJ14467.1 - 1.6 9.5 7.6 0.81 10.4 3.5 1.8 2 0 0 2 2 2 0 Stm1 IL5 PF02025.10 OAJ14468.1 - 0.082 12.9 0.1 0.95 9.5 0.0 2.1 2 0 0 2 2 2 0 Interleukin 5 DUF3719 PF12516.3 OAJ14471.1 - 0.1 12.1 0.4 0.35 10.4 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3719) DUF1295 PF06966.7 OAJ14490.1 - 4.6e-42 143.9 0.0 8.3e-42 143.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 OAJ14490.1 - 0.037 14.2 0.0 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1628 PF07790.6 OAJ14490.1 - 0.058 14.1 0.0 0.16 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) DUF4491 PF14898.1 OAJ14490.1 - 0.069 13.2 0.3 0.17 12.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) Steroid_dh PF02544.11 OAJ14490.1 - 0.083 12.6 0.0 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase Chorismate_synt PF01264.16 OAJ14491.1 - 1.2e-10 40.4 0.1 1.5e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 Chorismate synthase TGS PF02824.16 OAJ14493.1 - 1.4e-21 76.0 0.0 2.7e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 OAJ14493.1 - 1.7e-18 66.6 0.1 3.9e-18 65.5 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ14493.1 - 9.7e-10 37.9 0.1 2.7e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 OAJ14493.1 - 0.00027 20.7 0.1 0.099 12.4 0.0 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 OAJ14493.1 - 0.0082 15.5 0.5 6.2 6.2 0.1 3.4 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Miro PF08477.8 OAJ14493.1 - 0.012 16.0 0.0 0.035 14.5 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein ArgK PF03308.11 OAJ14493.1 - 0.018 13.7 0.6 0.042 12.6 0.1 1.8 2 0 0 2 2 2 0 ArgK protein PLDc_2 PF13091.1 OAJ14494.1 - 1.6e-13 50.5 0.0 5.4e-08 32.6 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain PIF1 PF05970.9 OAJ14497.1 - 5.6e-14 51.8 0.0 8.1e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ14498.1 - 3.3e-30 105.1 0.2 5.1e-30 104.5 0.2 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Abhydrolase_1 PF00561.15 OAJ14518.1 - 2e-17 63.5 0.0 2.4e-12 46.9 0.0 3.0 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 OAJ14518.1 - 3.6e-12 46.0 0.0 7.1e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 OAJ14518.1 - 2.5e-11 43.9 0.0 2e-10 40.9 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ14518.1 - 0.012 15.4 0.0 0.042 13.6 0.0 1.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family SMC_Nse1 PF07574.8 OAJ14519.1 - 3.9e-20 72.3 0.0 4.4e-11 42.7 0.0 2.2 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 OAJ14519.1 - 0.0016 18.3 8.0 0.0036 17.2 5.6 1.6 1 0 0 1 1 1 1 RING-like domain Myc_N PF01056.13 OAJ14519.1 - 0.0046 16.1 3.6 0.0067 15.6 2.5 1.3 1 0 0 1 1 1 1 Myc amino-terminal region BSP_II PF05432.6 OAJ14519.1 - 0.0049 16.2 13.1 0.0077 15.5 9.1 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Pox_Ag35 PF03286.9 OAJ14519.1 - 0.23 10.9 5.8 0.41 10.1 4.0 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FANCL_C PF11793.3 OAJ14519.1 - 1.5 8.8 5.5 6.5 6.7 3.4 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain PBP1_TM PF14812.1 OAJ14519.1 - 3 8.1 21.2 0.59 10.4 9.3 3.0 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PPP4R2 PF09184.6 OAJ14519.1 - 7.6 5.9 10.5 13 5.2 7.3 1.3 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.8 OAJ14519.1 - 8.5 4.0 9.2 14 3.3 6.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.27 OAJ14520.1 - 3.5e-33 112.2 14.5 5.3e-07 29.2 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat STE PF02200.11 OAJ14521.1 - 1.4e-34 118.5 0.1 2.4e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor DDE_Tnp_4 PF13359.1 OAJ14522.1 - 2.3e-33 115.0 0.0 3.6e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ14522.1 - 6.4e-08 32.2 0.0 3.3e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 OAJ14522.1 - 2.5e-05 23.9 0.1 0.00035 20.1 0.1 2.2 1 1 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.1 OAJ14522.1 - 0.00075 18.9 0.0 0.002 17.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_20 PF12840.2 OAJ14522.1 - 0.0032 17.2 0.1 0.019 14.7 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 OAJ14522.1 - 0.004 16.7 0.9 0.032 13.9 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 OAJ14522.1 - 0.01 15.8 0.1 0.051 13.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.7 OAJ14522.1 - 0.037 13.6 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 HTH domain V-ATPase_H_N PF03224.9 OAJ14522.1 - 0.094 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 V-ATPase subunit H zf-SNAP50_C PF12251.3 OAJ14524.1 - 1.1e-08 34.7 0.0 3.1e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal KCl_Cotrans_1 PF03522.10 OAJ14524.1 - 1.7 8.2 5.1 0.31 10.5 0.5 2.1 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) DUF4246 PF14033.1 OAJ14548.1 - 6.1e-119 397.8 0.1 7.4e-119 397.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-Fe_Oxy_2 PF10014.4 OAJ14548.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe dioxygenase PGAP1 PF07819.8 OAJ14549.1 - 5.6e-58 196.1 0.0 8.6e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 OAJ14549.1 - 0.027 13.7 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Utp12 PF04003.7 OAJ14550.1 - 0.069 13.0 0.4 0.069 13.0 0.3 1.4 2 0 0 2 2 2 0 Dip2/Utp12 Family Helicase_C PF00271.26 OAJ14552.1 - 1.8e-10 40.5 0.0 1.5e-08 34.3 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ14552.1 - 1.3e-08 34.5 0.0 2.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ14552.1 - 0.045 13.5 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Herpes_capsid PF06112.6 OAJ14552.1 - 0.088 12.8 7.8 0.16 11.9 5.4 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF87 PF01935.12 OAJ14552.1 - 4.6 6.9 4.6 15 5.3 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function DUF87 Rab5ip PF07019.7 OAJ14553.1 - 1.7e-09 37.6 2.7 2.8e-09 36.9 1.9 1.3 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) tRNA-synt_1e PF01406.14 OAJ14554.1 - 1.6e-120 401.7 0.1 1.8e-72 244.0 0.2 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 OAJ14554.1 - 1.8e-08 33.4 1.1 2.2e-05 23.2 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 OAJ14554.1 - 3.2e-05 22.1 0.2 0.0013 16.8 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 OAJ14554.1 - 0.00017 21.7 0.0 0.00017 21.7 0.0 2.8 4 0 0 4 4 4 1 DALR domain tRNA-synt_1c PF00749.16 OAJ14554.1 - 0.0039 15.8 0.5 0.83 8.2 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.13 OAJ14554.1 - 0.015 13.9 0.1 1.2 7.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) DUF3991 PF13154.1 OAJ14554.1 - 0.092 12.9 0.7 0.98 9.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3991) RTC4 PF14474.1 OAJ14576.1 - 0.063 13.2 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 RTC4-like domain RRN3 PF05327.6 OAJ14577.1 - 0.047 11.7 5.2 0.04 12.0 3.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.7 OAJ14577.1 - 0.048 12.9 15.1 0.05 12.8 10.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 OAJ14577.1 - 0.076 11.0 13.8 0.087 10.8 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 OAJ14577.1 - 0.19 11.7 6.9 0.27 11.2 4.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ycf1 PF05758.7 OAJ14577.1 - 0.24 9.0 3.2 0.23 9.1 2.2 1.0 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 OAJ14577.1 - 0.5 8.9 3.4 0.47 9.0 2.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Prog_receptor PF02161.10 OAJ14577.1 - 0.53 9.0 5.5 0.58 8.9 3.8 1.1 1 0 0 1 1 1 0 Progesterone receptor Daxx PF03344.10 OAJ14577.1 - 0.66 8.3 23.4 0.95 7.8 16.2 1.2 1 0 0 1 1 1 0 Daxx Family DUF2890 PF11081.3 OAJ14577.1 - 0.85 9.6 11.8 1.3 8.9 8.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 OAJ14577.1 - 0.87 7.4 26.4 1.1 7.0 18.3 1.0 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.9 OAJ14577.1 - 1.1 8.7 9.9 1.4 8.3 6.4 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CENP-T PF15511.1 OAJ14577.1 - 1.4 8.0 15.8 1.8 7.7 10.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Spore_coat_CotO PF14153.1 OAJ14577.1 - 2.8 7.3 9.2 3.7 6.9 6.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO TEX19 PF15553.1 OAJ14577.1 - 3.1 7.6 7.1 6.1 6.6 4.9 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF4637 PF15470.1 OAJ14577.1 - 3.2 7.3 12.6 4.4 6.8 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Tom22 PF04281.8 OAJ14577.1 - 4.9 6.6 11.9 6.9 6.2 8.2 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 TRAP_alpha PF03896.11 OAJ14577.1 - 4.9 6.0 13.9 6.4 5.6 9.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2201_N PF13203.1 OAJ14577.1 - 5.3 6.1 8.2 8.6 5.4 5.7 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain HSP90 PF00183.13 OAJ14577.1 - 5.7 5.2 14.1 7.4 4.8 9.8 1.1 1 0 0 1 1 1 0 Hsp90 protein YqfQ PF14181.1 OAJ14577.1 - 5.8 6.9 7.7 9.1 6.2 5.4 1.4 1 0 0 1 1 1 0 YqfQ-like protein Upf2 PF04050.9 OAJ14577.1 - 6.9 6.4 20.6 11 5.6 14.3 1.4 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Sporozoite_P67 PF05642.6 OAJ14577.1 - 7.1 4.3 9.2 9.9 3.8 6.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.4 OAJ14577.1 - 8.5 4.9 29.1 11 4.6 20.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SART-1 PF03343.8 OAJ14595.1 - 8.1e-109 364.6 52.9 9.7e-109 364.4 36.7 1.1 1 0 0 1 1 1 1 SART-1 family MFS_1 PF07690.11 OAJ14596.1 - 3.2e-41 141.2 29.9 3.2e-41 141.2 20.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ14596.1 - 9.3e-11 40.9 3.5 9.3e-11 40.9 2.4 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 OAJ14596.1 - 4.6 5.1 8.2 5.2 4.9 0.0 2.7 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Actin PF00022.14 OAJ14597.1 - 1.3e-58 198.3 0.0 4.5e-34 117.5 0.0 2.2 2 0 0 2 2 2 2 Actin Cornichon PF03311.9 OAJ14598.1 - 1.5e-52 177.0 11.1 1.7e-52 176.8 7.7 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1673 PF07895.6 OAJ14598.1 - 0.25 10.8 9.0 0.67 9.4 6.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) DUF1634 PF07843.6 OAJ14598.1 - 1.3 8.6 6.0 0.12 11.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) GTP_EFTU PF00009.22 OAJ14599.1 - 1e-21 77.2 0.0 3e-21 75.6 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 OAJ14599.1 - 1.9e-09 37.5 0.9 5.5e-09 36.0 0.6 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 OAJ14599.1 - 4e-06 26.9 0.8 0.067 13.3 0.0 2.7 2 1 1 3 3 3 2 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 OAJ14599.1 - 0.0044 16.9 0.0 0.013 15.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 OAJ14599.1 - 0.005 16.3 0.2 8.7 5.8 0.0 3.5 2 1 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.1 OAJ14599.1 - 0.0078 15.8 1.6 0.023 14.3 0.2 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Erythro-docking PF09277.6 OAJ14599.1 - 0.03 13.9 0.1 0.077 12.6 0.0 1.7 1 0 0 1 1 1 0 Erythronolide synthase, docking Miro PF08477.8 OAJ14599.1 - 0.17 12.4 0.7 1.2 9.5 0.5 2.5 1 1 0 1 1 1 0 Miro-like protein CBS PF00571.23 OAJ14600.1 - 3.5e-16 58.7 6.0 3.8e-05 23.4 0.5 5.3 5 0 0 5 5 5 4 CBS domain Rer1 PF03248.8 OAJ14602.1 - 3.1e-77 258.1 0.0 4.2e-77 257.7 0.0 1.2 1 0 0 1 1 1 1 Rer1 family RVT_1 PF00078.22 OAJ14617.1 - 2.5e-19 69.4 0.0 4.4e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ14617.1 - 9.6e-13 48.2 0.0 2.6e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain TFIIA PF03153.8 OAJ14619.1 - 0.79 9.5 10.9 0.94 9.3 7.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 OAJ14619.1 - 4.2 6.6 26.8 5.6 6.2 18.6 1.1 1 0 0 1 1 1 0 Vta1 like Chitin_synth_2 PF03142.10 OAJ14621.1 - 1.9e-243 808.6 0.0 2.5e-243 808.2 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 OAJ14621.1 - 8.4e-108 361.2 0.0 1.4e-107 360.4 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 OAJ14621.1 - 5.4e-18 65.4 3.0 5.4e-18 65.4 2.1 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ14621.1 - 6.5e-18 65.3 0.0 5.9e-15 55.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 OAJ14621.1 - 1.3e-16 60.1 0.1 1.5e-11 43.9 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 OAJ14621.1 - 2.7e-13 49.4 0.0 2.2e-11 43.3 0.0 2.6 2 0 0 2 2 2 1 DEK C terminal domain Glycos_transf_2 PF00535.21 OAJ14621.1 - 2e-09 37.3 0.0 7.8e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 OAJ14621.1 - 7.3e-07 28.6 0.0 1.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 MecA_N PF05223.6 OAJ14642.1 - 0.021 14.8 0.3 0.048 13.7 0.2 1.6 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain UQ_con PF00179.21 OAJ14643.1 - 3.8e-45 152.7 0.0 4.7e-45 152.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ14643.1 - 0.012 15.3 0.0 0.049 13.3 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B HTH_10 PF04967.7 OAJ14645.1 - 0.0013 18.2 0.0 0.0084 15.6 0.0 2.2 1 1 1 2 2 2 1 HTH DNA binding domain DSPc PF00782.15 OAJ14646.1 - 9.4e-19 67.3 0.0 4.3e-18 65.1 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAJ14646.1 - 0.086 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CPSase_L_D2 PF02786.12 OAJ14646.1 - 1.5 8.0 2.7 5.9 6.1 0.6 2.6 3 0 0 3 3 3 0 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF3128 PF11326.3 OAJ14648.1 - 4.2e-20 71.6 1.2 4.2e-20 71.6 0.9 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3128) Mus7 PF09462.5 OAJ14649.1 - 1.4e-107 361.1 0.0 1.9e-107 360.6 0.0 1.1 1 0 0 1 1 1 1 Mus7/MMS22 family MMS22L_N PF14910.1 OAJ14649.1 - 0.0039 15.4 0.0 0.0074 14.5 0.0 1.3 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, N-terminal ETF_QO PF05187.8 OAJ14666.1 - 1.5e-22 79.6 0.0 2.3e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DUF3016 PF11454.3 OAJ14666.1 - 0.025 14.1 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) Fer4_21 PF14697.1 OAJ14666.1 - 0.045 13.6 1.1 0.085 12.7 0.8 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 OAJ14666.1 - 0.071 13.0 0.3 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain Sigma_reg_N PF13800.1 OAJ14667.1 - 0.052 13.5 0.1 0.052 13.5 0.1 2.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal 7tm_7 PF08395.7 OAJ14667.1 - 9 5.1 18.1 0.067 12.2 6.1 2.1 3 0 0 3 3 3 0 7tm Chemosensory receptor Hexokinase_2 PF03727.11 OAJ14668.1 - 1.8e-80 269.6 0.0 2.6e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 OAJ14668.1 - 4.2e-66 222.2 0.0 9.1e-66 221.1 0.0 1.5 2 0 0 2 2 2 1 Hexokinase DEAD PF00270.24 OAJ14669.1 - 3.3e-37 127.5 0.1 6.4e-37 126.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ14669.1 - 7e-24 83.4 0.0 3.4e-23 81.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ14669.1 - 2.6e-05 24.1 0.2 6.7e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 OAJ14669.1 - 0.039 13.0 0.0 0.091 11.8 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit zf-C3HC4_2 PF13923.1 OAJ14670.1 - 1.3e-06 28.3 7.8 1.3e-06 28.3 5.4 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ14670.1 - 8.3e-06 25.3 2.2 8.3e-06 25.3 1.6 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ14670.1 - 7.3e-05 22.5 10.2 7.3e-05 22.5 7.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 OAJ14670.1 - 0.00013 21.7 4.4 0.00013 21.7 3.1 3.6 5 0 0 5 5 5 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 OAJ14670.1 - 0.00036 20.1 11.4 0.00036 20.1 7.9 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAJ14670.1 - 0.00078 19.1 1.7 0.00078 19.1 1.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 OAJ14670.1 - 0.0013 18.4 9.0 0.0013 18.4 6.2 2.9 2 1 0 2 2 2 1 zinc-RING finger domain LEM PF03020.10 OAJ14672.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 LEM domain DndB PF14072.1 OAJ14688.1 - 1.7e-103 346.4 0.0 1.9e-103 346.2 0.0 1.0 1 0 0 1 1 1 1 DNA-sulfur modification-associated Clp_N PF02861.15 OAJ14688.1 - 0.024 14.5 0.1 0.081 12.8 0.0 2.0 2 0 0 2 2 2 0 Clp amino terminal domain AAA_23 PF13476.1 OAJ14690.1 - 1.9e-11 44.7 0.8 1.9e-11 44.7 0.6 3.1 2 1 0 2 2 1 1 AAA domain SMC_N PF02463.14 OAJ14690.1 - 5.5e-09 35.5 4.2 0.00052 19.3 0.4 2.6 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain PAPS_reduct PF01507.14 OAJ14690.1 - 1.2e-08 35.0 0.0 1.2e-08 35.0 0.0 3.0 3 1 0 3 3 3 1 Phosphoadenosine phosphosulfate reductase family AAA_21 PF13304.1 OAJ14690.1 - 3.8e-05 23.7 0.0 0.041 13.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_13 PF13166.1 OAJ14690.1 - 0.0034 15.9 17.8 0.022 13.2 4.5 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 OAJ14690.1 - 0.0052 16.2 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain WGG PF10273.4 OAJ14690.1 - 0.0084 16.1 0.1 0.07 13.2 0.0 2.6 1 1 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Snapin_Pallidin PF14712.1 OAJ14690.1 - 0.052 13.8 29.1 0.64 10.3 3.2 4.9 3 1 1 4 4 4 0 Snapin/Pallidin ABC_tran PF00005.22 OAJ14690.1 - 0.14 12.4 7.8 9 6.5 0.0 4.1 2 1 0 2 2 2 0 ABC transporter DUF1664 PF07889.7 OAJ14690.1 - 0.3 10.8 13.2 2.9 7.7 0.9 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) cwf21 PF08312.7 OAJ14690.1 - 0.3 10.9 14.4 0.043 13.6 1.7 4.5 4 0 0 4 4 4 0 cwf21 domain Allexi_40kDa PF05549.6 OAJ14690.1 - 0.52 9.5 8.5 4.5 6.4 0.1 2.4 2 0 0 2 2 2 0 Allexivirus 40kDa protein Prominin PF05478.6 OAJ14690.1 - 2 5.8 10.8 0.35 8.3 3.4 2.0 2 0 0 2 2 2 0 Prominin Prefoldin_2 PF01920.15 OAJ14690.1 - 5.5 6.8 22.9 1.5 8.5 1.0 3.4 3 0 0 3 3 3 0 Prefoldin subunit Fmp27_WPPW PF10359.4 OAJ14690.1 - 5.7 5.2 17.6 3 6.1 2.3 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Fib_alpha PF08702.5 OAJ14690.1 - 7.9 6.5 15.4 20 5.3 0.6 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF421 PF04239.7 OAJ14691.1 - 7.3e-21 73.5 0.0 9.8e-21 73.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF421) Y1_Tnp PF01797.11 OAJ14693.1 - 1.6e-05 24.7 0.1 2.2e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Transposase IS200 like ABC1 PF03109.11 OAJ14693.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Aminotran_4 PF01063.14 OAJ14694.1 - 5.7e-24 84.8 0.0 7.3e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class IV Acetyltransf_6 PF13480.1 OAJ14694.1 - 0.04 13.8 0.6 2.4 8.1 0.0 2.8 3 1 0 4 4 4 0 Acetyltransferase (GNAT) domain Isochorismatase PF00857.15 OAJ14695.1 - 3.6e-22 79.1 0.0 4.5e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family MerR_1 PF13411.1 OAJ14697.1 - 4.8e-13 48.6 0.3 8.8e-13 47.8 0.0 1.5 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.18 OAJ14697.1 - 3.8e-09 35.9 1.3 3.8e-09 35.9 0.9 1.7 2 0 0 2 2 2 1 MerR family regulatory protein MerR-DNA-bind PF09278.6 OAJ14697.1 - 7.9e-06 26.1 0.7 1e-05 25.8 0.5 1.2 1 0 0 1 1 1 1 MerR, DNA binding Bro-N PF02498.12 OAJ14698.1 - 1.9e-07 31.2 0.0 2.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 BRO family, N-terminal domain Imm26 PF15572.1 OAJ14698.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 26 PAAR_motif PF05488.8 OAJ14699.1 - 1.4e-18 66.6 4.3 2.5e-15 56.1 0.3 2.4 1 1 1 2 2 2 2 PAAR motif DUF4150 PF13665.1 OAJ14699.1 - 0.0035 17.2 2.3 0.27 11.1 0.0 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4150) RVT_3 PF13456.1 OAJ14700.1 - 0.059 13.1 0.4 0.18 11.6 0.2 1.7 1 1 1 2 2 2 0 Reverse transcriptase-like HTH_22 PF13309.1 OAJ14700.1 - 0.088 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 HTH domain FUSC PF04632.7 OAJ14700.1 - 0.52 8.6 5.9 0.61 8.4 4.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family He_PIG PF05345.7 OAJ14701.1 - 0.00071 19.5 0.1 0.00071 19.5 0.1 1.6 2 0 0 2 2 2 1 Putative Ig domain Ank_2 PF12796.2 OAJ14719.1 - 2.2e-11 43.9 0.0 1.5e-10 41.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ14719.1 - 3.8e-10 39.0 0.4 0.023 14.4 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 OAJ14719.1 - 2e-07 31.3 0.2 0.0085 16.5 0.0 4.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ14719.1 - 8.5e-07 29.0 0.3 0.085 13.1 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ14719.1 - 9.2e-05 22.3 0.0 17 6.0 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat RVP PF00077.15 OAJ14719.1 - 0.17 11.8 0.0 22 5.0 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease GCR1_C PF12550.3 OAJ14720.1 - 3.2e-05 23.6 0.0 7.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_Tnp_1 PF01527.15 OAJ14720.1 - 0.031 14.2 0.3 0.2 11.6 0.0 2.6 2 0 0 2 2 2 0 Transposase HTH_23 PF13384.1 OAJ14720.1 - 0.043 13.4 2.2 0.2 11.3 0.0 3.4 3 0 0 3 3 3 0 Homeodomain-like domain HTH_28 PF13518.1 OAJ14720.1 - 0.11 12.5 3.1 0.31 11.0 0.0 3.3 4 0 0 4 4 4 0 Helix-turn-helix domain OB_NTP_bind PF07717.11 OAJ14721.1 - 1.9e-17 63.0 0.0 6.9e-17 61.3 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 OAJ14721.1 - 3.7e-13 49.3 1.5 4.9e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ14721.1 - 7.1e-09 35.4 0.0 1.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ14721.1 - 0.00046 19.7 0.8 0.21 11.0 0.1 2.4 1 1 0 2 2 2 2 DEAD/DEAH box helicase T2SE PF00437.15 OAJ14721.1 - 0.00077 18.4 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 OAJ14721.1 - 0.0035 16.8 0.0 0.038 13.4 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 OAJ14721.1 - 0.004 17.3 0.1 0.44 10.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain ResIII PF04851.10 OAJ14721.1 - 0.0065 16.3 0.0 0.96 9.2 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 OAJ14721.1 - 0.076 12.5 1.2 0.31 10.5 0.0 2.4 2 1 0 3 3 3 0 AAA domain PhoH PF02562.11 OAJ14721.1 - 0.14 11.3 0.2 0.73 9.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein zf-C2H2 PF00096.21 OAJ14722.1 - 4.5e-25 86.4 56.9 0.0014 18.8 0.4 10.6 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ14722.1 - 1.3e-21 75.2 56.4 0.0035 17.5 0.7 10.6 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ14722.1 - 1.1e-06 28.5 4.9 0.00097 19.3 1.5 12.6 14 1 0 14 14 14 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 OAJ14722.1 - 4.6e-06 26.6 17.2 2.7 8.2 0.0 7.6 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding RNase_H2_suC PF08615.6 OAJ14723.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF1741 PF08427.5 OAJ14724.1 - 5e-11 42.5 1.7 0.00011 21.7 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF1741) Ribosomal_L7Ae PF01248.21 OAJ14740.1 - 6.6e-22 76.8 0.1 1.5e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 OAJ14740.1 - 0.0023 17.7 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 Daxx PF03344.10 OAJ14740.1 - 0.41 9.0 14.7 0.52 8.7 10.2 1.1 1 0 0 1 1 1 0 Daxx Family Utp14 PF04615.8 OAJ14740.1 - 1.7 6.7 24.0 2 6.4 16.6 1.1 1 0 0 1 1 1 0 Utp14 protein APC_CDC26 PF10471.4 OAJ14740.1 - 6.3 7.6 8.5 2.4 8.9 0.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Fe-S_biosyn PF01521.15 OAJ14741.1 - 1e-14 54.4 0.0 1.5e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis MutS_V PF00488.16 OAJ14743.1 - 7.4e-79 264.4 0.3 1.3e-78 263.6 0.1 1.6 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 OAJ14743.1 - 1.4e-42 145.8 0.4 1.4e-42 145.8 0.3 2.1 3 0 0 3 3 3 1 MutS domain III MutS_I PF01624.15 OAJ14743.1 - 4e-34 117.0 0.5 1.2e-33 115.5 0.0 2.1 2 0 0 2 2 2 1 MutS domain I zf-C2H2_3 PF13878.1 OAJ14743.1 - 1.8e-12 46.6 2.0 3.7e-12 45.6 1.4 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO MutS_II PF05188.12 OAJ14743.1 - 5.5e-12 45.9 0.2 1.7e-11 44.3 0.1 1.9 1 0 0 1 1 1 1 MutS domain II Acetyltransf_13 PF13880.1 OAJ14743.1 - 3e-10 39.6 0.0 1.2e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 ESCO1/2 acetyl-transferase MutS_IV PF05190.13 OAJ14743.1 - 2.8e-06 27.3 0.4 1.3e-05 25.2 0.1 2.2 2 0 0 2 2 2 1 MutS family domain IV SKN1 PF03935.10 OAJ14744.1 - 5.6e-174 579.0 0.7 6.5e-174 578.7 0.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 OAJ14744.1 - 1.6e-06 27.5 0.3 0.012 14.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 RhoGEF PF00621.15 OAJ14745.1 - 4.7e-29 101.5 0.5 1.2e-28 100.1 0.3 1.6 1 0 0 1 1 1 1 RhoGEF domain PPR_2 PF13041.1 OAJ14766.1 - 1.3e-35 121.1 0.0 1.3e-11 44.2 0.0 9.3 8 2 3 11 11 11 6 PPR repeat family PPR_3 PF13812.1 OAJ14766.1 - 3.5e-32 107.9 2.0 1.6e-05 24.7 0.0 10.8 11 0 0 11 11 11 5 Pentatricopeptide repeat domain PPR PF01535.15 OAJ14766.1 - 3.1e-27 92.6 5.2 9.9e-05 22.0 0.0 11.2 11 2 0 11 11 11 5 PPR repeat PPR_1 PF12854.2 OAJ14766.1 - 3.2e-19 68.0 3.7 5.6e-07 28.9 0.0 7.0 9 1 0 9 9 9 3 PPR repeat TPR_7 PF13176.1 OAJ14766.1 - 0.0027 17.3 0.0 8.2 6.4 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ14766.1 - 0.11 12.3 0.0 28 4.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Cyclin_N PF00134.18 OAJ14767.1 - 9.4e-39 131.8 0.9 7.8e-38 128.9 0.3 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ14767.1 - 5.9e-26 90.7 0.0 1.2e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain CBF PF03914.12 OAJ14768.1 - 5.8e-34 116.9 0.0 4.4e-33 114.0 0.0 2.5 1 1 0 1 1 1 1 CBF/Mak21 family Adaptin_N PF01602.15 OAJ14768.1 - 0.083 11.1 0.0 0.79 7.9 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region DUF4510 PF14971.1 OAJ14770.1 - 0.02 15.0 1.4 0.37 10.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) Transposase_21 PF02992.9 OAJ14790.1 - 3.2e-21 75.4 0.0 4.9e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ14790.1 - 0.14 11.6 0.1 0.26 10.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Ebola_NP PF05505.7 OAJ14791.1 - 0.57 8.1 4.9 0.64 8.0 3.4 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein SDA1 PF05285.7 OAJ14791.1 - 1.3 8.1 12.1 1.5 8.0 8.4 1.1 1 0 0 1 1 1 0 SDA1 GCR1_C PF12550.3 OAJ14792.1 - 9.2e-15 54.2 0.0 1.9e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Sporozoite_P67 PF05642.6 OAJ14792.1 - 0.037 11.9 3.7 0.065 11.0 2.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF572 PF04502.8 OAJ14792.1 - 2.1 7.4 8.2 0.21 10.7 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) ATP_synt_H PF05493.8 OAJ14793.1 - 1.1e-21 76.6 2.9 1.3e-21 76.3 2.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit H Claudin_2 PF13903.1 OAJ14793.1 - 0.15 11.7 6.3 0.17 11.5 4.3 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF4131 PF13567.1 OAJ14793.1 - 0.34 10.2 2.0 0.39 10.1 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Xan_ur_permease PF00860.15 OAJ14793.1 - 0.38 9.1 3.5 0.57 8.6 2.4 1.4 1 1 0 1 1 1 0 Permease family DUF2456 PF10445.4 OAJ14793.1 - 0.49 10.3 2.7 7.8 6.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) Abhydrolase_3 PF07859.8 OAJ14794.1 - 3.6e-31 108.3 0.1 1.6e-21 76.9 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 OAJ14812.1 - 1.4e-38 132.5 0.0 1.2e-30 106.6 0.0 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold DUF2424 PF10340.4 OAJ14812.1 - 8.2e-11 41.1 0.0 2.6e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 OAJ14812.1 - 3.5e-05 23.6 0.0 8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 OAJ14812.1 - 0.084 11.5 0.1 0.65 8.6 0.0 2.5 4 0 0 4 4 4 0 Carboxylesterase family Peptidase_S9 PF00326.16 OAJ14812.1 - 0.086 12.0 0.0 0.21 10.7 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family AXE1 PF05448.7 OAJ14812.1 - 0.19 10.1 0.0 0.37 9.2 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) GCR1_C PF12550.3 OAJ14813.1 - 5.2e-09 35.8 0.6 5.2e-09 35.8 0.4 1.8 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Phage_integrase PF00589.17 OAJ14813.1 - 3.8e-08 33.2 0.0 1.1e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 Phage integrase family Got1 PF04178.7 OAJ14815.1 - 1.6e-22 79.7 22.3 2.3e-22 79.3 15.5 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Herpes_capsid PF06112.6 OAJ14815.1 - 4.5 7.3 5.7 5.6 7.0 4.0 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF4187 PF13821.1 OAJ14816.1 - 1.8e-15 56.2 4.9 4.5e-15 54.9 3.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 OAJ14816.1 - 0.12 12.1 0.1 0.41 10.4 0.0 1.8 1 0 0 1 1 1 0 G-patch domain AP-5_subunit_s1 PF15001.1 OAJ14816.1 - 0.53 10.1 2.2 1.2 9.0 1.5 1.6 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 DPBB_1 PF03330.13 OAJ14817.1 - 2.4e-06 27.4 0.1 3.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Zip PF02535.17 OAJ14817.1 - 0.023 13.7 0.7 0.018 14.0 0.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Barwin PF00967.12 OAJ14817.1 - 0.028 14.0 0.2 0.064 12.9 0.1 1.6 1 1 0 1 1 1 0 Barwin family SelP_N PF04592.9 OAJ14817.1 - 0.35 10.2 8.3 0.48 9.7 5.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ribonuc_red_sm PF00268.16 OAJ14818.1 - 5.7e-120 399.5 1.6 6.9e-120 399.2 1.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Glyco_transf_90 PF05686.7 OAJ14831.1 - 1.2e-25 90.0 6.6 1.1e-22 80.2 4.6 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF3533 PF12051.3 OAJ14832.1 - 4.1e-75 252.9 11.1 4.9e-75 252.6 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.2 OAJ14832.1 - 4.1e-05 22.7 17.0 7.8e-05 21.8 11.8 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein Ibs_toxin PF13956.1 OAJ14832.1 - 0.11 12.3 0.3 0.11 12.3 0.2 2.4 2 0 0 2 2 2 0 Toxin Ibs, type I toxin-antitoxin system Cytochrom_B561 PF03188.11 OAJ14833.1 - 1.3e-08 34.7 9.8 1.3e-08 34.7 6.8 1.9 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.12 OAJ14833.1 - 0.0012 18.7 0.2 0.0026 17.6 0.1 1.6 1 1 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 OAJ14833.1 - 0.32 10.5 8.6 0.11 12.1 3.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF4173 PF13777.1 OAJ14833.1 - 3.4 6.9 6.1 0.76 9.0 0.3 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4173) DUF3533 PF12051.3 OAJ14834.1 - 4.4e-82 275.8 18.2 5.2e-82 275.6 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) HAD_2 PF13419.1 OAJ14835.1 - 1.6e-14 54.5 0.0 4.5e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAJ14835.1 - 2.2e-12 47.8 1.0 4.5e-12 46.8 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAJ14835.1 - 2.9e-07 30.0 0.0 7.3e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 OAJ14835.1 - 0.0097 16.0 0.0 0.023 14.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GDPD PF03009.12 OAJ14836.1 - 1.2e-34 120.0 1.6 3.4e-34 118.5 1.1 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 OAJ14836.1 - 0.0024 18.0 2.7 0.0024 18.0 1.8 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DUF2905 PF11146.3 OAJ14837.1 - 0.11 12.4 0.8 0.19 11.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2905) Esterase PF00756.15 OAJ14856.1 - 0.00026 20.5 0.0 0.00041 19.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 OAJ14856.1 - 0.013 15.2 0.2 0.027 14.2 0.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_S9 PF00380.14 OAJ14856.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S9/S16 Herpes_capsid PF06112.6 OAJ14856.1 - 6.3 6.8 9.2 17 5.4 6.4 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein FHA PF00498.21 OAJ14857.1 - 3.5e-15 55.8 0.0 5.7e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 FHA domain DUF4611 PF15387.1 OAJ14857.1 - 1.9 8.6 11.6 0.041 14.0 0.6 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4611) Pox_MCEL PF03291.11 OAJ14858.1 - 1.2e-68 231.4 0.0 1.6e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.1 OAJ14858.1 - 1.7e-11 43.9 0.0 2.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ14858.1 - 5.4e-09 35.9 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ14858.1 - 1.2e-08 35.2 0.0 2.8e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ14858.1 - 1.9e-08 34.8 0.0 4.2e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ14858.1 - 2e-06 28.0 0.0 4.2e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ14858.1 - 3.5e-06 27.3 0.0 9.7e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 OAJ14858.1 - 0.0003 19.8 0.0 0.0017 17.3 0.0 1.9 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family MTS PF05175.9 OAJ14858.1 - 0.00096 18.5 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 OAJ14858.1 - 0.022 13.9 0.1 0.072 12.1 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MetW PF07021.7 OAJ14858.1 - 0.53 9.6 0.0 0.89 8.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW WD40 PF00400.27 OAJ14859.1 - 2.1e-40 135.1 18.5 2.3e-08 33.5 0.5 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat DUF2415 PF10313.4 OAJ14859.1 - 0.002 17.7 0.0 0.15 11.7 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Gaa1 PF04114.9 OAJ14860.1 - 2.7e-45 155.0 6.1 6.5e-21 74.6 0.0 4.1 4 0 0 4 4 4 4 Gaa1-like, GPI transamidase component LRR_6 PF13516.1 OAJ14861.1 - 3.4e-18 63.6 0.3 0.46 10.7 0.0 8.9 10 0 0 10 10 9 3 Leucine Rich repeat LRR_4 PF12799.2 OAJ14861.1 - 1e-11 44.1 8.5 0.089 12.4 0.2 6.3 4 2 3 7 7 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 OAJ14861.1 - 3.6e-09 35.3 0.6 9.5 6.7 0.0 7.8 8 1 0 8 8 7 1 Leucine Rich Repeat LRR_8 PF13855.1 OAJ14861.1 - 1.6e-08 34.1 9.0 0.17 11.6 0.1 6.1 3 2 2 6 6 6 4 Leucine rich repeat LRR_7 PF13504.1 OAJ14861.1 - 6.9e-05 22.4 10.2 17 6.1 0.0 7.7 9 0 0 9 9 8 0 Leucine rich repeat Abhydrolase_5 PF12695.2 OAJ14861.1 - 0.048 13.4 0.1 0.46 10.2 0.0 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ14861.1 - 0.069 13.0 0.6 0.16 11.8 0.3 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2457 PF10446.4 OAJ14861.1 - 0.091 11.4 21.1 0.12 11.0 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TMEM247 PF15444.1 OAJ14861.1 - 0.18 11.5 6.4 0.32 10.7 4.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 Sigma70_ner PF04546.8 OAJ14861.1 - 1 8.9 16.0 1.7 8.2 11.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region TraH_2 PF06871.6 OAJ14861.1 - 1.1 8.6 4.9 1.9 7.8 3.4 1.3 1 0 0 1 1 1 0 TraH_2 Nop14 PF04147.7 OAJ14861.1 - 3.1 5.5 20.0 4.2 5.1 13.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 OAJ14861.1 - 3.8 6.8 11.4 5.7 6.2 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Paf1 PF03985.8 OAJ14861.1 - 6.1 5.4 13.7 8.2 5.0 9.5 1.1 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.9 OAJ14861.1 - 8.6 4.2 12.9 12 3.8 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein CS PF04969.11 OAJ14862.1 - 1.6e-05 25.3 0.1 3.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 CS domain Oxidored_q6 PF01058.17 OAJ14881.1 - 8.6e-23 80.3 0.1 1.3e-22 79.7 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit OPT PF03169.10 OAJ14882.1 - 2.3e-180 601.1 54.1 2.6e-180 600.9 37.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pkinase PF00069.20 OAJ14883.1 - 1.3e-63 214.5 0.0 2.1e-63 213.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ14883.1 - 2.7e-33 115.1 0.0 4e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ14883.1 - 3.2e-07 29.5 0.0 4.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ14883.1 - 0.00027 20.7 0.1 0.00071 19.3 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ14883.1 - 0.0046 16.0 0.0 0.0091 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GCR1_C PF12550.3 OAJ14884.1 - 2.2e-21 75.4 0.8 4.3e-21 74.5 0.5 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes OPT PF03169.10 OAJ14885.1 - 2.1e-188 627.6 54.1 2.4e-188 627.4 37.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Dimer_Tnp_hAT PF05699.9 OAJ14886.1 - 1.8e-23 81.9 0.0 3.9e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAJ14886.1 - 0.0097 15.8 0.0 0.33 10.9 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4413) zf-BED PF02892.10 OAJ14886.1 - 0.028 14.1 0.4 0.067 12.9 0.3 1.6 1 0 0 1 1 1 0 BED zinc finger zinc_ribbon_5 PF13719.1 OAJ14886.1 - 0.053 13.1 0.6 0.1 12.1 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 OAJ14886.1 - 0.11 12.2 1.1 0.22 11.2 0.8 1.4 1 0 0 1 1 1 0 zinc-ribbon domain PP_kinase_C PF13090.1 OAJ14886.1 - 0.26 9.8 0.0 0.4 9.2 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain Glyco_hydro_32N PF00251.15 OAJ14906.1 - 4.2e-38 131.4 0.0 1.9e-36 126.0 0.0 2.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 OAJ14906.1 - 8.4e-11 42.1 0.0 1.8e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Pkinase PF00069.20 OAJ14907.1 - 2.3e-74 249.8 0.1 2.3e-74 249.8 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ14907.1 - 5.2e-53 179.7 1.1 1.4e-52 178.3 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 OAJ14907.1 - 7e-21 74.4 0.1 3.9e-20 72.0 0.0 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.24 OAJ14907.1 - 7.1e-10 39.0 1.4 1.5e-09 38.0 1.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 OAJ14907.1 - 9.5e-07 28.0 0.0 1.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 OAJ14907.1 - 0.00049 20.3 0.7 0.046 13.9 0.5 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 OAJ14907.1 - 0.0039 16.9 4.1 0.01 15.6 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1777 PF08648.7 OAJ14907.1 - 0.0061 16.3 7.9 0.015 15.0 5.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Rotamase PF00639.16 OAJ14907.1 - 1.6 9.5 7.1 4.3 8.1 4.9 1.8 1 0 0 1 1 1 0 PPIC-type PPIASE domain DUF2514 PF10721.4 OAJ14907.1 - 5.8 6.5 28.6 12 5.5 19.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) RQC PF09382.5 OAJ14933.1 - 6.2e-23 80.5 0.1 1.2e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 OAJ14933.1 - 4.9e-20 71.6 0.0 1.3e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ14933.1 - 1.1e-19 70.0 0.0 1.9e-18 66.0 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.18 OAJ14933.1 - 1.8e-10 40.3 0.0 4.4e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Ribosomal_S9 PF00380.14 OAJ14934.1 - 9.8e-36 122.6 0.0 2e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Fungal_trans PF04082.13 OAJ14935.1 - 4.8e-19 68.2 0.0 1.4e-18 66.6 0.0 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Abhydrolase_1 PF00561.15 OAJ14936.1 - 3.4e-17 62.7 0.1 6.9e-13 48.6 0.1 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ14936.1 - 1.4e-10 41.4 1.7 4e-09 36.6 1.2 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAJ14936.1 - 3.4e-05 23.3 0.1 5.7e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 OAJ14936.1 - 0.00078 19.2 0.0 0.03 14.0 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Sterol-sensing PF12349.3 OAJ14937.1 - 1.1e-38 132.1 12.9 2.7e-38 130.8 8.9 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 OAJ14937.1 - 4.4e-12 44.7 5.1 6.4e-12 44.2 3.5 1.1 1 0 0 1 1 1 1 Patched family His_Phos_2 PF00328.17 OAJ14938.1 - 1.8e-69 234.7 0.3 2.6e-69 234.2 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 OAJ14938.1 - 1.1e-06 28.2 0.0 2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DIOX_N PF14226.1 OAJ14959.1 - 2.6e-14 53.7 0.0 5.1e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAJ14959.1 - 2.4e-13 50.2 0.0 4e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SNF2_N PF00176.18 OAJ14960.1 - 1.8e-71 240.4 0.3 2.9e-71 239.6 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ14960.1 - 2.5e-14 52.8 0.0 9.8e-14 50.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ14960.1 - 3.7e-08 33.4 0.1 1.3e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ14960.1 - 3.3e-05 23.4 0.0 0.00011 21.7 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSA PF07529.8 OAJ14960.1 - 0.0017 18.0 8.1 0.0017 18.0 5.6 2.7 2 1 1 3 3 3 1 HSA HDA2-3 PF11496.3 OAJ14960.1 - 0.012 14.4 0.5 2.6 6.7 0.1 2.5 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 NmrA PF05368.8 OAJ14962.1 - 1.7e-15 56.9 0.0 1.9e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAJ14962.1 - 0.0011 19.0 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAJ14962.1 - 0.024 13.3 0.1 0.034 12.8 0.1 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 OAJ14962.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UPF0121 PF03661.8 OAJ14963.1 - 1.4e-20 73.5 7.1 3.2e-20 72.4 4.9 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF2101 PF09874.4 OAJ14963.1 - 0.06 12.8 0.1 0.06 12.8 0.1 2.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2101) DeoC PF01791.4 OAJ14964.1 - 2.5e-34 118.6 2.5 6e-33 114.1 1.7 2.0 1 1 0 1 1 1 1 DeoC/LacD family aldolase RebB PF11747.3 OAJ14964.1 - 0.03 14.1 7.7 0.12 12.2 5.3 2.0 1 0 0 1 1 1 0 Killing trait PMT PF02366.13 OAJ14965.1 - 4.5e-41 140.8 4.7 6e-41 140.4 3.3 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PTR2 PF00854.16 OAJ14966.1 - 0.1 11.3 1.1 0.13 11.0 0.8 1.1 1 0 0 1 1 1 0 POT family PT PF04886.7 OAJ14967.1 - 0.036 13.3 7.1 1.1 8.6 0.3 4.2 3 1 2 5 5 5 0 PT repeat DDE_Tnp_4 PF13359.1 OAJ14984.1 - 1.9e-26 92.5 0.0 2.9e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ14984.1 - 2.4e-07 30.3 0.0 4.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 OAJ14984.1 - 0.0017 18.4 1.2 0.002 18.2 0.0 1.6 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.16 OAJ14984.1 - 0.0052 16.3 0.0 0.013 15.0 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain Myb_DNA-bind_3 PF12776.2 OAJ14985.1 - 3.4e-16 59.6 2.8 4.8e-16 59.1 1.9 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ14985.1 - 2.2e-07 30.9 3.5 3.4e-07 30.3 2.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ14985.1 - 0.0011 19.0 1.7 0.0024 17.9 1.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 OAJ14985.1 - 0.016 15.1 3.2 0.016 15.1 2.2 1.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain YebG PF07130.7 OAJ14985.1 - 0.074 12.7 0.4 0.62 9.7 0.0 2.2 2 0 0 2 2 2 0 YebG protein NOA36 PF06524.7 OAJ14985.1 - 0.35 10.0 3.5 0.47 9.6 2.4 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.8 OAJ14985.1 - 5.7 4.5 7.1 8.6 3.9 4.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi VWA_2 PF13519.1 OAJ14986.1 - 1.4e-16 61.1 0.3 1.4e-16 61.1 0.2 1.6 2 1 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.9 OAJ14986.1 - 7.4e-08 32.2 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 OAJ14986.1 - 6.2e-07 29.2 1.5 1e-06 28.5 0.2 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 OAJ14986.1 - 0.0051 16.2 11.9 0.1 12.2 1.1 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif Chorismate_bind PF00425.13 OAJ14986.1 - 0.068 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 chorismate binding enzyme CAF1 PF04857.15 OAJ14987.1 - 2.1e-64 217.3 0.0 3.1e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Peptidase_M24 PF00557.19 OAJ14988.1 - 2.3e-42 144.9 0.0 2.8e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DDE_Tnp_4 PF13359.1 OAJ14989.1 - 3.4e-21 75.4 0.0 6.1e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease IncA PF04156.9 OAJ14990.1 - 0.017 14.6 0.3 0.029 13.9 0.2 1.3 1 0 0 1 1 1 0 IncA protein G-alpha PF00503.15 OAJ14991.1 - 7.8e-134 446.2 2.0 9.5e-134 445.9 1.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 OAJ14991.1 - 7.7e-17 61.0 0.7 7.9e-12 44.7 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ14991.1 - 9.1e-05 21.7 1.0 0.013 14.6 0.0 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 OAJ14991.1 - 0.00055 20.4 0.1 0.78 10.2 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein zf-CHC2 PF01807.15 OAJ14991.1 - 0.0022 17.5 0.0 0.0077 15.7 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger AAA_29 PF13555.1 OAJ14991.1 - 0.0058 16.1 0.2 0.039 13.4 0.1 2.2 1 1 1 2 2 2 1 P-loop containing region of AAA domain MCM PF00493.18 OAJ14991.1 - 0.009 14.8 0.0 0.02 13.7 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MMR_HSR1 PF01926.18 OAJ14991.1 - 0.013 15.4 0.0 4 7.4 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 OAJ14991.1 - 0.035 13.5 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 OAJ14991.1 - 0.063 12.6 0.0 2.5 7.5 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 OAJ14991.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Arm PF00514.18 OAJ14992.1 - 2.6e-74 242.7 9.5 8.8e-12 44.3 0.0 8.5 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 OAJ14992.1 - 2.5e-27 94.9 8.8 5.9e-08 32.8 0.1 6.0 2 1 4 6 6 6 5 HEAT repeats HEAT_EZ PF13513.1 OAJ14992.1 - 7.8e-19 67.5 5.1 2.3e-07 31.0 0.0 5.9 3 3 3 6 6 6 5 HEAT-like repeat HEAT PF02985.17 OAJ14992.1 - 1.7e-15 55.5 1.8 0.0015 18.4 0.0 7.2 7 0 0 7 7 7 3 HEAT repeat IBB PF01749.15 OAJ14992.1 - 5.6e-12 45.6 0.6 1.1e-11 44.7 0.4 1.5 1 0 0 1 1 1 1 Importin beta binding domain RICTOR_V PF14668.1 OAJ14992.1 - 0.00018 21.3 2.2 0.37 10.7 0.0 3.7 3 2 1 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.15 OAJ14992.1 - 0.0011 17.4 0.0 0.0033 15.8 0.0 1.8 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_PBS PF03130.11 OAJ14992.1 - 0.015 15.7 4.3 2.2 9.0 0.0 4.9 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 OAJ14992.1 - 0.24 9.6 0.0 8.7 4.4 0.0 2.3 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit DUF737 PF05300.6 OAJ15010.1 - 0.0028 17.6 10.0 0.0039 17.1 6.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF737) tRNA-synt_1e PF01406.14 OAJ15010.1 - 0.3 10.1 2.7 0.46 9.5 1.9 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain BTV_NS2 PF04514.7 OAJ15010.1 - 2.8 6.7 13.3 3.7 6.3 9.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 ABC_tran PF00005.22 OAJ15011.1 - 4.8e-37 127.3 1.4 1.1e-19 71.1 0.0 3.9 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 OAJ15011.1 - 2.2e-10 40.9 0.1 0.00011 22.2 0.0 4.2 4 0 0 4 4 4 1 AAA domain SMC_N PF02463.14 OAJ15011.1 - 1.2e-07 31.2 2.5 0.28 10.3 0.1 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_tran_2 PF12848.2 OAJ15011.1 - 2.8e-06 27.0 3.6 2.8e-06 27.0 2.5 2.5 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 OAJ15011.1 - 8.6e-06 25.1 0.2 0.019 14.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 OAJ15011.1 - 4.3e-05 23.3 0.0 0.002 18.0 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 OAJ15011.1 - 7.2e-05 22.0 0.5 0.0054 15.9 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 OAJ15011.1 - 0.00026 21.3 1.4 1.2 9.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 OAJ15011.1 - 0.0021 17.9 0.0 0.13 12.1 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 OAJ15011.1 - 0.0032 16.9 0.2 2.8 7.2 0.0 3.4 3 0 0 3 3 3 1 AAA-like domain ArgK PF03308.11 OAJ15011.1 - 0.0051 15.6 0.9 0.024 13.4 0.3 2.1 2 0 0 2 2 2 1 ArgK protein NACHT PF05729.7 OAJ15011.1 - 0.012 15.2 0.0 5.8 6.5 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 OAJ15011.1 - 0.037 14.1 0.3 2.2 8.4 0.0 3.4 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 OAJ15011.1 - 0.044 13.9 0.0 2.8 8.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 OAJ15011.1 - 0.074 12.7 0.6 14 5.3 0.0 3.8 5 0 0 5 5 5 0 AAA domain (dynein-related subfamily) Aa_trans PF01490.13 OAJ15012.1 - 5.2e-07 28.5 0.3 0.00099 17.6 0.2 2.6 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein tRNA_bind PF01588.15 OAJ15016.1 - 2.3e-27 94.6 0.0 3.9e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.20 OAJ15016.1 - 0.0052 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ15016.1 - 0.0083 15.9 0.1 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Menin PF05053.8 OAJ15016.1 - 2.2 6.3 5.1 0.87 7.6 1.3 1.9 2 0 0 2 2 2 0 Menin Zn_clus PF00172.13 OAJ15017.1 - 1.1e-11 44.4 7.1 1.8e-11 43.7 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transaldolase PF00923.14 OAJ15039.1 - 9.2e-98 326.8 0.3 1.1e-97 326.7 0.2 1.0 1 0 0 1 1 1 1 Transaldolase Imm31 PF15595.1 OAJ15039.1 - 0.069 12.9 0.1 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Immunity protein 31 Pkinase PF00069.20 OAJ15041.1 - 5.2e-07 29.0 0.1 1.5e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Seadorna_VP7 PF07387.6 OAJ15041.1 - 0.00035 19.4 0.0 0.00052 18.9 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 OAJ15041.1 - 0.00038 20.2 0.0 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ15041.1 - 0.046 12.7 3.7 0.079 12.0 2.6 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ15041.1 - 0.21 10.5 0.0 0.39 9.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Zip PF02535.17 OAJ15041.1 - 8.8 5.2 9.8 6.9 5.5 0.5 2.6 2 0 0 2 2 2 0 ZIP Zinc transporter AAA PF00004.24 OAJ15042.1 - 4e-44 150.0 0.1 9.6e-44 148.7 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAJ15042.1 - 7.2e-09 35.4 0.0 4.4e-08 32.9 0.1 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 OAJ15042.1 - 2.1e-07 31.0 0.1 5.6e-07 29.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 OAJ15042.1 - 2.6e-06 27.5 0.1 1.2e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ15042.1 - 3.2e-06 27.3 0.5 0.0021 18.1 0.0 2.8 2 1 1 3 3 2 1 AAA domain DUF815 PF05673.8 OAJ15042.1 - 5.9e-06 25.3 0.0 3e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 OAJ15042.1 - 0.00034 20.5 0.1 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ15042.1 - 0.00051 19.7 0.1 0.0017 18.0 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 OAJ15042.1 - 0.00056 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 OAJ15042.1 - 0.0012 18.6 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 NTPase RuvB_N PF05496.7 OAJ15042.1 - 0.0012 17.8 0.0 0.0027 16.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 OAJ15042.1 - 0.0013 19.4 0.1 0.0072 17.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 OAJ15042.1 - 0.0026 16.5 0.0 0.0057 15.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 OAJ15042.1 - 0.0027 17.6 0.0 0.0073 16.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 OAJ15042.1 - 0.003 17.2 0.1 0.045 13.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 OAJ15042.1 - 0.0033 17.7 0.0 0.018 15.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAJ15042.1 - 0.0035 17.2 0.0 0.011 15.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain Arch_ATPase PF01637.13 OAJ15042.1 - 0.0042 16.8 0.6 0.12 12.0 0.0 2.9 3 1 1 4 4 3 1 Archaeal ATPase AAA_11 PF13086.1 OAJ15042.1 - 0.0042 16.7 0.0 0.029 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 OAJ15042.1 - 0.0051 16.9 0.0 0.013 15.6 0.0 1.7 2 0 0 2 2 1 1 RNA helicase Mg_chelatase PF01078.16 OAJ15042.1 - 0.0069 15.5 0.1 0.019 14.1 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 OAJ15042.1 - 0.0082 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 OAJ15042.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 OAJ15042.1 - 0.01 15.4 0.0 0.029 14.0 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 OAJ15042.1 - 0.012 15.0 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Bac_DnaA PF00308.13 OAJ15042.1 - 0.02 14.5 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_24 PF13479.1 OAJ15042.1 - 0.021 14.3 0.2 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAJ15042.1 - 0.031 13.6 4.2 0.047 13.0 0.1 2.6 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.1 OAJ15042.1 - 0.047 14.0 1.1 0.58 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 OAJ15042.1 - 0.055 12.3 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 OAJ15042.1 - 0.13 11.7 0.1 1.8 7.9 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 OAJ15042.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArfGap PF01412.13 OAJ15043.1 - 3.6e-41 139.6 0.2 3.6e-41 139.6 0.1 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf AAA_23 PF13476.1 OAJ15043.1 - 2.1 8.6 10.1 0.88 9.8 5.4 1.4 2 0 0 2 2 2 0 AAA domain DUF3573 PF12097.3 OAJ15043.1 - 2.6 6.5 10.5 4.5 5.7 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF3373 PF11853.3 OAJ15043.1 - 5.7 5.3 11.1 8.9 4.7 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) NUDIX PF00293.23 OAJ15045.1 - 0.00055 19.5 0.0 0.00097 18.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SCP2 PF02036.12 OAJ15046.1 - 6.5e-26 90.5 1.0 7.3e-26 90.4 0.7 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 OAJ15046.1 - 8.9e-05 22.4 0.5 0.00011 22.1 0.4 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal UPF0197 PF05251.7 OAJ15047.1 - 0.00062 20.0 1.1 0.00088 19.5 0.7 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) Fig1 PF12351.3 OAJ15047.1 - 0.0073 16.2 0.6 0.0073 16.2 0.4 1.0 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 Aminotran_1_2 PF00155.16 OAJ15048.1 - 1.3e-80 271.0 0.0 1.5e-80 270.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Med21 PF11221.3 OAJ15062.1 - 0.19 11.6 1.4 0.21 11.5 0.2 1.7 2 0 0 2 2 2 0 Subunit 21 of Mediator complex SWIRM PF04433.12 OAJ15063.1 - 1.2e-33 115.1 0.0 2.2e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 OAJ15063.1 - 2.8e-08 33.1 0.8 4.8e-08 32.4 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 OAJ15063.1 - 7.3e-07 29.2 0.0 2.1e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 OAJ15063.1 - 7.9e-05 22.6 0.1 0.00017 21.5 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2450 PF10475.4 OAJ15063.1 - 0.23 10.3 0.5 0.44 9.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) ODC_AZ PF02100.12 OAJ15065.1 - 5e-15 54.9 0.0 1.2e-14 53.7 0.0 1.5 1 1 0 1 1 1 1 Ornithine decarboxylase antizyme LAGLIDADG_3 PF14528.1 OAJ15066.1 - 1.9e-05 24.7 0.0 0.00042 20.5 0.0 2.4 2 0 0 2 2 2 1 LAGLIDADG-like domain Hom_end PF05204.9 OAJ15066.1 - 0.0092 15.9 0.0 0.41 10.6 0.0 2.5 2 0 0 2 2 2 1 Homing endonuclease Pcc1 PF09341.5 OAJ15087.1 - 1.2e-20 73.2 0.9 1.5e-20 73.0 0.6 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF3323 PF11796.3 OAJ15088.1 - 0.00026 20.3 0.6 0.00026 20.3 0.4 2.2 2 0 0 2 2 2 1 Protein of unknown function N-terminus (DUF3323) Eclosion PF04736.7 OAJ15088.1 - 0.05 13.0 0.3 0.088 12.2 0.2 1.3 1 0 0 1 1 1 0 Eclosion hormone DUF3318 PF11780.3 OAJ15090.1 - 0.051 13.1 0.7 0.11 12.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) MSP1_C PF07462.6 OAJ15091.1 - 4.1 5.6 5.6 0.83 7.9 0.2 1.9 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus GATA PF00320.22 OAJ15092.1 - 3.3e-05 23.1 1.7 5.4e-05 22.4 1.2 1.4 1 0 0 1 1 1 1 GATA zinc finger Rod_cone_degen PF15201.1 OAJ15092.1 - 0.058 13.2 1.5 0.14 12.0 0.1 2.4 3 0 0 3 3 3 0 Progressive rod-cone degeneration T2SM PF04612.7 OAJ15092.1 - 1.1 9.0 5.9 0.55 10.0 2.2 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Gag_spuma PF03276.9 OAJ15092.1 - 2.9 6.0 12.3 4.2 5.5 8.5 1.3 1 0 0 1 1 1 0 Spumavirus gag protein MCPVI PF02993.9 OAJ15092.1 - 7.5 6.6 7.2 1.7 8.7 2.2 1.8 2 0 0 2 2 2 0 Minor capsid protein VI zf-DHHC PF01529.15 OAJ15093.1 - 8.8e-39 132.6 2.1 1.2e-38 132.2 0.6 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase SR-25 PF10500.4 OAJ15093.1 - 0.001 18.5 16.7 0.001 18.5 11.6 2.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Arc_PepC_II PF06847.6 OAJ15093.1 - 0.26 11.7 1.3 0.94 9.9 0.9 1.9 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Sigma70_ner PF04546.8 OAJ15093.1 - 6.2 6.3 20.4 1.5 8.4 6.6 3.3 3 0 0 3 3 3 0 Sigma-70, non-essential region MOSC_N PF03476.11 OAJ15094.1 - 2.4e-17 62.7 0.0 4.7e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 OAJ15094.1 - 6.5e-08 32.1 0.1 0.2 11.0 0.0 3.4 3 1 0 3 3 3 3 MOSC domain zf-RING_2 PF13639.1 OAJ15095.1 - 1.6e-09 37.4 4.8 1.6e-09 37.4 3.3 2.7 2 1 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 OAJ15095.1 - 6.5e-09 35.7 0.7 6.5e-09 35.7 0.5 1.7 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_3 PF14369.1 OAJ15095.1 - 1.5e-06 28.0 1.1 1.5e-06 28.0 0.8 3.0 3 0 0 3 3 3 1 zinc-finger zf-C3HC4_3 PF13920.1 OAJ15095.1 - 2.3e-06 27.1 9.8 5e-06 26.0 2.2 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ15095.1 - 6.3e-06 26.1 0.6 6.3e-06 26.1 0.4 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ15095.1 - 3.7e-05 23.3 0.6 3.7e-05 23.3 0.4 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 OAJ15095.1 - 0.00058 19.6 2.3 0.0018 18.0 1.6 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 OAJ15095.1 - 0.00072 19.1 2.2 0.00072 19.1 1.5 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 OAJ15095.1 - 0.017 14.9 1.6 0.043 13.6 1.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.2 OAJ15095.1 - 0.04 13.7 3.8 1.4 8.8 0.1 3.1 3 0 0 3 3 3 0 Double zinc ribbon FANCL_C PF11793.3 OAJ15095.1 - 0.073 13.0 4.2 1.2 9.1 2.9 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain Zn-ribbon_8 PF09723.5 OAJ15095.1 - 0.16 11.9 6.0 0.29 11.0 0.4 3.0 3 0 0 3 3 3 0 Zinc ribbon domain HypA PF01155.14 OAJ15095.1 - 0.85 9.3 3.2 0.79 9.4 0.1 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Prok-RING_4 PF14447.1 OAJ15095.1 - 2 8.0 6.4 0.089 12.3 0.4 1.8 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 Mit_KHE1 PF10173.4 OAJ15113.1 - 5.8e-52 176.2 0.8 8.3e-52 175.7 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Histone PF00125.19 OAJ15114.1 - 5.6e-19 68.0 0.1 8.1e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 ATP_bind_1 PF03029.12 OAJ15115.1 - 4.6e-71 239.1 0.0 1.5e-66 224.3 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 OAJ15115.1 - 0.00057 19.8 0.0 0.0031 17.4 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 OAJ15115.1 - 0.00059 19.9 0.1 0.0016 18.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ15115.1 - 0.0014 19.4 0.1 0.0014 19.4 0.1 2.5 2 1 0 2 2 1 1 AAA domain AAA_10 PF12846.2 OAJ15115.1 - 0.0014 18.0 0.2 0.2 11.0 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 OAJ15115.1 - 0.0015 18.4 0.2 0.0041 16.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 OAJ15115.1 - 0.0016 17.9 0.6 0.0092 15.4 0.2 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CbiA PF01656.18 OAJ15115.1 - 0.0036 16.7 0.7 0.13 11.6 0.5 2.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 OAJ15115.1 - 0.01 15.4 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 OAJ15115.1 - 0.016 14.8 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 OAJ15115.1 - 0.017 14.5 0.3 0.055 12.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 OAJ15115.1 - 0.022 13.6 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ArgK PF03308.11 OAJ15115.1 - 0.029 13.1 0.1 1.8 7.2 0.0 2.4 2 0 0 2 2 2 0 ArgK protein AAA_29 PF13555.1 OAJ15115.1 - 0.034 13.6 0.1 0.07 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 OAJ15115.1 - 0.069 13.4 0.1 0.069 13.4 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 OAJ15115.1 - 0.11 12.0 0.2 0.42 10.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 OAJ15115.1 - 0.16 12.4 0.1 6.2 7.3 0.1 2.4 2 0 0 2 2 2 0 Miro-like protein Viral_helicase1 PF01443.13 OAJ15115.1 - 0.21 11.0 0.1 0.48 9.9 0.1 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.12 OAJ15115.1 - 2.7 7.7 5.8 0.46 10.2 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF87 Thymidylate_kin PF02223.12 OAJ15115.1 - 3.7 6.8 5.1 10 5.4 0.0 2.6 3 0 0 3 3 3 0 Thymidylate kinase Thiolase_N PF00108.18 OAJ15116.1 - 4.5e-71 238.9 0.0 6.4e-71 238.4 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAJ15116.1 - 2.7e-41 139.8 0.6 8.6e-41 138.2 0.3 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 OAJ15116.1 - 0.00031 20.3 0.1 0.0099 15.5 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 OAJ15116.1 - 0.0066 16.4 0.2 0.021 14.8 0.1 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 OAJ15116.1 - 0.0096 15.4 2.7 0.042 13.3 0.5 2.8 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain NADHdh_A3 PF14987.1 OAJ15117.1 - 0.05 13.5 0.0 0.063 13.1 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 NADH_B2 PF14813.1 OAJ15118.1 - 0.0078 15.8 0.3 0.0095 15.5 0.2 1.3 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Ribosomal_S16 PF00886.14 OAJ15119.1 - 1.6e-24 85.3 3.9 5.3e-24 83.7 2.7 1.8 1 1 0 1 1 1 1 Ribosomal protein S16 VWA_2 PF13519.1 OAJ15120.1 - 1e-13 51.7 0.1 6.1e-13 49.2 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 OAJ15120.1 - 3.7e-05 23.5 0.0 8.7e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.3 OAJ15120.1 - 0.051 12.5 0.0 0.094 11.7 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A Integrin_beta PF00362.13 OAJ15120.1 - 0.14 11.0 0.0 3.4 6.4 0.0 2.0 1 1 1 2 2 2 0 Integrin, beta chain Ribosomal_L14 PF00238.14 OAJ15121.1 - 1.1e-32 112.3 0.0 2.2e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Kri1_C PF12936.2 OAJ15121.1 - 3.8e-23 81.2 0.1 3.8e-23 81.2 0.0 4.0 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 OAJ15121.1 - 3.8e-21 75.2 11.5 3.8e-21 75.2 8.0 5.1 4 1 1 5 5 5 1 KRI1-like family RRM_6 PF14259.1 OAJ15122.1 - 1.6e-33 114.4 0.0 2e-11 43.7 0.0 4.8 5 0 0 5 5 5 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ15122.1 - 2.1e-32 110.5 0.0 1.6e-12 46.8 0.0 4.0 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ15122.1 - 1.5e-14 53.5 0.0 1.4e-06 28.0 0.0 3.7 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAJ15122.1 - 5.9e-07 29.1 0.0 0.011 15.4 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 OAJ15122.1 - 0.00079 19.1 0.0 0.011 15.4 0.0 2.6 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 OAJ15122.1 - 0.045 13.7 0.0 0.51 10.3 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain DUF4651 PF15513.1 OAJ15122.1 - 0.073 12.5 0.1 27 4.2 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4651) FAD_binding_3 PF01494.14 OAJ15145.1 - 1.1e-24 87.1 0.0 1.5e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAJ15145.1 - 0.00048 20.0 0.0 0.0045 16.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ15145.1 - 0.0031 17.8 0.1 0.049 14.0 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ15145.1 - 0.009 14.9 0.9 0.19 10.6 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.5 OAJ15145.1 - 0.023 13.5 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase ApbA PF02558.11 OAJ15145.1 - 0.034 13.5 0.1 0.064 12.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.1 OAJ15145.1 - 0.044 13.8 0.1 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Autophagy_N PF03986.8 OAJ15145.1 - 0.048 13.4 0.1 0.096 12.4 0.1 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain RabGAP-TBC PF00566.13 OAJ15147.1 - 9.9e-16 57.8 0.0 4.3e-06 26.3 0.0 3.6 3 1 0 3 3 3 2 Rab-GTPase-TBC domain FAM176 PF14851.1 OAJ15147.1 - 3.4 7.3 3.3 4.5 6.9 0.0 2.6 3 0 0 3 3 3 0 FAM176 family Transposase_21 PF02992.9 OAJ15148.1 - 2.4e-12 46.4 0.0 3.8e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ15148.1 - 7.2e-06 25.4 0.2 1.3e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) PspB PF06667.7 OAJ15151.1 - 0.0022 17.8 1.3 0.0022 17.8 0.9 3.2 2 1 1 3 3 3 1 Phage shock protein B FlaC_arch PF05377.6 OAJ15151.1 - 0.048 13.5 6.9 0.52 10.2 0.4 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) FlxA PF14282.1 OAJ15151.1 - 0.14 12.0 11.0 0.62 10.0 2.9 2.4 1 1 1 2 2 2 0 FlxA-like protein Peptidase_S46 PF10459.4 OAJ15151.1 - 0.46 8.8 16.7 0.6 8.4 11.5 1.0 1 0 0 1 1 1 0 Peptidase S46 DivIC PF04977.10 OAJ15151.1 - 1 8.8 18.4 0.04 13.4 2.1 2.9 3 0 0 3 3 3 0 Septum formation initiator AKNA PF12443.3 OAJ15151.1 - 2.2 8.3 10.7 0.37 10.8 0.4 2.9 1 1 1 3 3 3 0 AT-hook-containing transcription factor DNA_pol3_a_NII PF11490.3 OAJ15151.1 - 5.3 6.6 9.5 6.4 6.4 1.8 2.5 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II TSC22 PF01166.13 OAJ15151.1 - 6.5 6.8 11.4 2.3 8.2 0.8 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family HAD_2 PF13419.1 OAJ15171.1 - 7e-11 42.6 0.0 8.1e-08 32.6 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAJ15171.1 - 0.02 14.6 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like COX6B PF02297.12 OAJ15171.1 - 0.099 12.6 0.3 0.19 11.7 0.0 1.5 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb DUF1295 PF06966.7 OAJ15172.1 - 3.5e-35 121.4 0.1 2.4e-34 118.6 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) Collagen PF01391.13 OAJ15174.1 - 1.8e-28 97.8 130.4 2.7e-11 42.8 25.1 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Pro_isomerase PF00160.16 OAJ15176.1 - 7.2e-41 139.9 0.0 1.3e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 OAJ15176.1 - 0.0027 16.9 0.0 0.0027 16.9 0.0 2.7 3 1 0 3 3 3 1 Rtf2 RING-finger DUF2373 PF10180.4 OAJ15177.1 - 1.3e-14 53.4 0.1 1.6e-10 40.3 0.1 2.3 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) NOT2_3_5 PF04153.13 OAJ15177.1 - 0.12 12.2 0.3 0.27 11.1 0.2 1.5 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family CDC45 PF02724.9 OAJ15177.1 - 5.9 4.7 7.5 8.9 4.2 5.2 1.6 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S8 PF00082.17 OAJ15178.1 - 6.3e-24 84.6 0.0 3.6e-11 42.7 0.0 2.5 1 1 1 2 2 2 2 Subtilase family PA PF02225.17 OAJ15178.1 - 6.2e-09 35.4 0.0 1.8e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 PA domain Thioredoxin PF00085.15 OAJ15196.1 - 8.7e-21 73.5 0.0 9.5e-21 73.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 OAJ15196.1 - 7.6e-05 22.7 0.0 0.00055 20.0 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ15196.1 - 0.00071 19.7 0.0 0.0038 17.4 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 OAJ15196.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.3 1 1 0 1 1 1 0 AhpC/TSA family DUF2847 PF11009.3 OAJ15196.1 - 0.026 14.1 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Redoxin PF08534.5 OAJ15196.1 - 0.11 12.0 0.1 2.7 7.5 0.0 2.0 1 1 1 2 2 2 0 Redoxin HyaE PF07449.6 OAJ15196.1 - 0.12 12.2 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE PRP21_like_P PF12230.3 OAJ15197.1 - 0.056 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-C3HC4_2 PF13923.1 OAJ15197.1 - 0.22 11.5 11.6 0.39 10.7 8.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lipocalin_5 PF13924.1 OAJ15199.1 - 0.019 14.6 0.1 0.031 13.9 0.1 1.2 1 0 0 1 1 1 0 Lipocalin-like domain IFT43 PF15305.1 OAJ15200.1 - 3.1 7.8 6.2 26 4.8 4.3 2.0 1 1 0 1 1 1 0 Intraflagellar transport protein 43 GTP_cyclohydro2 PF00925.15 OAJ15201.1 - 4.1e-61 205.1 0.0 2.6e-55 186.2 0.0 2.4 2 0 0 2 2 2 2 GTP cyclohydrolase II EF-hand_7 PF13499.1 OAJ15202.1 - 2.9e-13 49.7 0.0 4e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 OAJ15202.1 - 2.8e-12 45.4 0.2 2.4e-05 23.8 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 OAJ15202.1 - 6.9e-12 43.7 0.1 1.1e-05 24.4 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 OAJ15202.1 - 6e-09 35.7 0.0 3.3e-05 23.7 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 OAJ15202.1 - 4.1e-05 23.1 0.3 0.013 15.1 0.0 3.7 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 OAJ15202.1 - 0.0052 16.0 0.3 0.079 12.3 0.0 2.7 2 0 0 2 2 2 1 EF hand EFhand_Ca_insen PF08726.5 OAJ15202.1 - 0.025 14.5 0.0 0.15 12.0 0.0 2.2 2 1 0 2 2 2 0 Ca2+ insensitive EF hand UPF0154 PF03672.8 OAJ15202.1 - 0.035 13.7 0.0 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) TFIID-18kDa PF02269.11 OAJ15203.1 - 2.1e-17 62.7 0.1 2.7e-07 30.2 0.2 2.1 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit Serglycin PF04360.7 OAJ15203.1 - 0.019 14.6 5.7 0.019 14.6 3.9 1.8 2 0 0 2 2 2 0 Serglycin GLTSCR1 PF15249.1 OAJ15203.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region FAM75 PF14650.1 OAJ15203.1 - 0.18 11.1 4.6 0.24 10.7 3.2 1.1 1 0 0 1 1 1 0 FAM75 family DUF3678 PF12435.3 OAJ15204.1 - 1.9 8.1 4.5 4.7 6.8 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Se-cys_synth_N PF12390.3 OAJ15204.1 - 3 8.0 5.5 61 3.8 3.2 3.1 1 1 1 2 2 2 0 Selenocysteine synthase N terminal Abhydrolase_6 PF12697.2 OAJ15205.1 - 4e-24 85.7 0.5 5.3e-24 85.3 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ15205.1 - 7.3e-18 64.7 0.1 2.7e-16 59.6 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 OAJ15205.1 - 4e-10 39.5 0.0 5.2e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 OAJ15205.1 - 1.3e-08 33.7 0.0 5.3e-06 25.1 0.0 2.8 3 0 0 3 3 3 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 OAJ15205.1 - 4.4e-08 32.6 0.0 1.2e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 OAJ15205.1 - 3.6e-07 29.6 0.0 5.6e-06 25.7 0.0 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 OAJ15205.1 - 1.8e-06 27.6 0.0 8.2e-05 22.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 OAJ15205.1 - 7.4e-06 25.8 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 OAJ15205.1 - 0.0002 21.1 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 OAJ15205.1 - 0.00081 18.8 0.1 0.0085 15.5 0.1 2.0 1 1 0 1 1 1 1 Putative esterase Peptidase_S28 PF05577.7 OAJ15205.1 - 0.0019 16.8 0.0 0.0026 16.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 PAF-AH_p_II PF03403.8 OAJ15205.1 - 0.0038 15.5 0.0 1.2 7.3 0.0 2.3 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.8 OAJ15205.1 - 0.0061 16.1 0.3 0.017 14.7 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1100 PF06500.6 OAJ15205.1 - 0.064 11.8 0.0 0.085 11.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_2 PF02230.11 OAJ15205.1 - 0.16 11.3 0.0 17 4.7 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase tRNA-synt_1 PF00133.17 OAJ15227.1 - 3e-43 147.7 0.0 1.2e-34 119.3 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 OAJ15227.1 - 2.6e-15 56.0 0.0 6.7e-09 34.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 OAJ15227.1 - 7.7e-11 41.9 0.0 1.9e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 OAJ15227.1 - 2.8e-07 29.9 0.0 5.6e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 OAJ15227.1 - 0.011 15.0 0.2 0.21 10.8 0.0 2.4 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 HVSL PF09749.4 OAJ15228.1 - 2.4e-35 121.7 0.0 3.4e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein SR-25 PF10500.4 OAJ15228.1 - 1 8.7 4.3 1.7 8.0 3.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NYN PF01936.13 OAJ15229.1 - 1.6e-22 80.3 0.0 4.2e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 NYN domain adh_short_C2 PF13561.1 OAJ15230.1 - 4.4e-29 101.9 0.0 5e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ15230.1 - 6e-17 62.0 0.3 7.4e-17 61.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ15230.1 - 4.8e-07 29.6 0.2 7e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAJ15230.1 - 0.021 14.8 0.1 0.041 13.8 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding Shikimate_DH PF01488.15 OAJ15230.1 - 0.023 14.7 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 OAJ15230.1 - 0.027 13.5 0.2 0.067 12.2 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 OAJ15230.1 - 0.08 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Eno-Rase_NADH_b PF12242.3 OAJ15230.1 - 0.094 12.5 0.4 0.21 11.4 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 OAJ15230.1 - 0.1 12.0 0.2 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family PIG-P PF08510.7 OAJ15231.1 - 5.3e-24 84.2 4.8 9.2e-24 83.4 2.9 1.5 1 1 1 2 2 2 1 PIG-P RabGAP-TBC PF00566.13 OAJ15232.1 - 1.1e-28 100.2 6.8 2.4e-28 99.0 0.0 3.3 4 0 0 4 4 4 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 OAJ15232.1 - 1.5e-05 24.3 0.0 8.4e-05 21.9 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3548) DUF1348 PF07080.6 OAJ15233.1 - 5e-49 165.7 4.7 6.1e-49 165.5 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 OAJ15233.1 - 4.4e-07 30.2 0.0 6.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 OAJ15233.1 - 0.009 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.1 OAJ15233.1 - 0.018 14.9 0.1 0.039 13.8 0.0 1.5 2 0 0 2 2 2 0 SnoaL-like domain SnoaL PF07366.7 OAJ15233.1 - 0.031 13.8 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase JmjC PF02373.17 OAJ15254.1 - 0.004 17.3 0.0 0.0043 17.2 0.0 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase TMF_DNA_bd PF12329.3 OAJ15255.1 - 0.13 12.1 1.3 0.2 11.4 0.9 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding GCR1_C PF12550.3 OAJ15256.1 - 1.5e-17 63.2 0.3 4.3e-17 61.7 0.2 1.8 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Phage_int_SAM_1 PF02899.12 OAJ15256.1 - 0.84 9.8 5.3 1.1 9.4 0.4 3.5 3 1 1 4 4 4 0 Phage integrase, N-terminal SAM-like domain AMP-binding PF00501.23 OAJ15273.1 - 1.1e-86 290.8 0.2 5.3e-56 189.7 0.9 2.2 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ15273.1 - 3.9e-18 66.1 0.1 1.3e-17 64.4 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3651 PF12371.3 OAJ15273.1 - 0.0087 16.0 0.3 7.3 6.6 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3651) PTH2 PF01981.11 OAJ15275.1 - 6.6e-49 164.4 1.1 8.5e-49 164.0 0.8 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Rabaptin PF03528.10 OAJ15275.1 - 0.06 13.2 0.1 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Rabaptin TPR_16 PF13432.1 OAJ15275.1 - 0.43 11.3 0.2 0.43 11.3 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat NDUFA12 PF05071.11 OAJ15276.1 - 3.7e-24 85.1 0.2 4.7e-24 84.8 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 RVT_1 PF00078.22 OAJ15277.1 - 2.1e-10 40.3 0.0 5.7e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RabGAP-TBC PF00566.13 OAJ15279.1 - 3e-44 151.0 0.3 6.4e-44 149.9 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Asp_protease PF09668.5 OAJ15280.1 - 6.3e-60 200.1 0.0 9e-60 199.6 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 OAJ15280.1 - 2e-10 41.0 0.0 5.8e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 OAJ15280.1 - 3.5e-10 39.1 0.0 6.4e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.1 OAJ15280.1 - 6.6e-07 29.0 0.3 3.6e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 OAJ15280.1 - 1.9e-05 24.6 0.0 3.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 OAJ15280.1 - 0.00042 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP PF00077.15 OAJ15280.1 - 0.0007 19.4 0.0 0.0023 17.8 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease Ubiquitin_2 PF14560.1 OAJ15280.1 - 0.0034 17.5 0.0 0.0092 16.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain Profilin PF00235.14 OAJ15281.1 - 1.3e-39 135.0 0.0 1.4e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Profilin DASH_Dad2 PF08654.5 OAJ15282.1 - 2.8e-21 75.4 0.0 6.5e-21 74.2 0.0 1.6 1 1 0 1 1 1 1 DASH complex subunit Dad2 Yippee-Mis18 PF03226.9 OAJ15302.1 - 1.8e-11 43.9 0.0 4.4e-11 42.6 0.0 1.7 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Tom22 PF04281.8 OAJ15303.1 - 5.3e-38 129.6 3.1 4.7e-35 120.0 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial import receptor subunit Tom22 Shadoo PF14999.1 OAJ15303.1 - 0.012 15.4 5.2 0.021 14.7 3.6 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Retinal PF15449.1 OAJ15303.1 - 0.22 9.1 1.3 0.27 8.8 0.9 1.1 1 0 0 1 1 1 0 Retinal protein RXT2_N PF08595.6 OAJ15303.1 - 0.41 10.4 3.6 0.72 9.6 2.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal YL1 PF05764.8 OAJ15303.1 - 1.6 8.2 6.5 2.5 7.6 4.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Daxx PF03344.10 OAJ15303.1 - 3 6.2 7.3 4 5.8 5.0 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 OAJ15303.1 - 3.6 5.4 9.7 4.1 5.2 6.7 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.5 OAJ15303.1 - 8.4 6.6 12.5 16 5.8 8.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PHD PF00628.24 OAJ15304.1 - 1.6e-05 24.5 19.2 2.6e-05 23.8 13.3 1.4 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 OAJ15305.1 - 1.5e-17 64.3 0.1 1.5e-17 64.3 0.1 4.4 3 2 0 3 3 3 1 SET domain Ribosomal_L6e PF01159.14 OAJ15307.1 - 7.3e-34 116.2 0.2 7.3e-34 116.2 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 OAJ15307.1 - 0.00076 19.3 2.3 0.00076 19.3 1.6 2.1 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain rve PF00665.21 OAJ15324.1 - 7.1e-20 71.3 0.1 3.1e-19 69.2 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ15324.1 - 6e-15 55.1 0.0 1.2e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 OAJ15324.1 - 0.0029 17.4 2.5 0.0076 16.1 1.7 1.8 1 0 0 1 1 1 1 Zinc knuckle rve_3 PF13683.1 OAJ15324.1 - 0.0068 15.9 0.0 0.024 14.1 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ15324.1 - 0.031 14.7 0.0 0.086 13.3 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.1 OAJ15324.1 - 0.068 12.6 1.0 0.14 11.6 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.1 OAJ15324.1 - 0.088 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_4 PF14392.1 OAJ15324.1 - 0.54 9.9 2.6 4.5 7.0 1.4 2.5 2 0 0 2 2 2 0 Zinc knuckle Init_tRNA_PT PF04179.7 OAJ15325.1 - 4e-98 329.2 0.0 4.9e-98 328.9 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Fungal_trans PF04082.13 OAJ15326.1 - 3.1e-10 39.3 0.0 6e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ15326.1 - 7.1e-08 32.2 6.1 1.2e-07 31.4 4.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dehydrin PF00257.14 OAJ15326.1 - 0.34 11.2 12.6 2 8.7 1.8 3.2 3 0 0 3 3 3 0 Dehydrin Apolipoprotein PF01442.13 OAJ15327.1 - 0.0011 18.4 0.0 0.0011 18.4 0.0 6.1 3 2 1 4 4 4 1 Apolipoprotein A1/A4/E domain DUF1283 PF06932.6 OAJ15327.1 - 0.061 13.3 0.9 0.21 11.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) LEA_4 PF02987.11 OAJ15327.1 - 0.25 11.2 17.2 0.047 13.5 0.6 4.6 3 0 0 3 3 3 0 Late embryogenesis abundant protein Kinesin PF00225.18 OAJ15328.1 - 2e-92 309.4 0.0 3.3e-92 308.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain FlgN PF05130.7 OAJ15328.1 - 0.2 11.8 5.1 0.8 9.9 0.1 2.5 2 0 0 2 2 2 0 FlgN protein DUF2422 PF10337.4 OAJ15344.1 - 1.2e-63 215.5 2.2 3.8e-63 213.8 1.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 OAJ15344.1 - 1.6e-44 152.2 0.1 2.7e-44 151.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 OAJ15344.1 - 5.2e-05 23.1 27.1 0.0011 18.9 10.4 3.9 2 1 1 3 3 3 2 Fusaric acid resistance protein-like AATF-Che1 PF13339.1 OAJ15344.1 - 0.07 13.2 0.9 0.16 12.0 0.7 1.6 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor C2 PF00168.25 OAJ15345.1 - 3.3e-18 65.2 0.0 7e-14 51.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain DDE_Tnp_1_6 PF13751.1 OAJ15345.1 - 0.047 13.7 0.4 0.12 12.3 0.3 1.7 1 0 0 1 1 1 0 Transposase DDE domain SDA1 PF05285.7 OAJ15348.1 - 0.041 13.1 28.4 0.075 12.2 19.7 1.4 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 OAJ15348.1 - 0.3 9.5 25.5 0.42 9.0 17.7 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 OAJ15348.1 - 1.7 6.6 18.8 2.4 6.0 13.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 OAJ15348.1 - 2.5 7.4 23.1 6.6 6.0 16.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ADIP PF11559.3 OAJ15348.1 - 3.9 7.3 19.6 0.068 13.0 7.8 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 OAJ15348.1 - 8.7 5.1 10.0 13 4.6 6.6 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4218 PF13960.1 OAJ15369.1 - 0.00047 19.6 0.0 0.00078 18.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) UPRTase PF14681.1 OAJ15370.1 - 0.071 12.3 0.1 0.16 11.1 0.1 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase RVT_1 PF00078.22 OAJ15374.1 - 2.3e-25 89.2 0.0 5.2e-25 88.0 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dimer_Tnp_hAT PF05699.9 OAJ15376.1 - 1.6e-12 46.8 0.0 3.8e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAJ15376.1 - 0.069 13.1 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Pkinase PF00069.20 OAJ15377.1 - 8.1e-40 136.5 0.0 9.9e-40 136.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ15377.1 - 5.3e-17 61.7 0.0 8.2e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ15377.1 - 2.6e-06 26.6 0.0 4.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ15377.1 - 0.00069 18.7 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TrkH PF02386.11 OAJ15398.1 - 1.8e-89 299.7 10.3 2.1e-87 293.0 2.4 2.1 2 0 0 2 2 2 2 Cation transport protein APC_CDC26 PF10471.4 OAJ15399.1 - 4.5e-07 30.5 4.7 1.3e-06 29.0 3.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 RNR_inhib PF08591.5 OAJ15399.1 - 0.11 13.4 1.4 0.29 12.0 1.0 1.6 1 1 1 2 2 2 0 Ribonucleotide reductase inhibitor MHYT PF03707.11 OAJ15400.1 - 5.3e-12 45.6 19.8 2.9e-06 27.2 1.3 4.6 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat Fis1_TPR_C PF14853.1 OAJ15401.1 - 9.6e-24 83.0 0.3 1.5e-23 82.4 0.2 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 OAJ15401.1 - 2.3e-13 49.1 0.0 4.9e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 OAJ15401.1 - 0.00092 18.9 0.6 0.0028 17.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ15401.1 - 0.0012 19.4 0.4 0.011 16.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ15401.1 - 0.028 14.8 1.9 17 6.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ15401.1 - 0.05 14.2 1.3 0.42 11.3 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ15401.1 - 0.077 13.3 1.3 0.4 11.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ15401.1 - 0.24 11.9 1.0 0.79 10.3 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ESCRT-II PF05871.7 OAJ15402.1 - 2.4e-44 150.6 0.0 7.2e-44 149.0 0.0 1.7 1 1 1 2 2 2 1 ESCRT-II complex subunit FeoC PF09012.5 OAJ15402.1 - 0.15 11.7 0.0 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 FeoC like transcriptional regulator ORMDL PF04061.9 OAJ15403.1 - 5.8e-07 29.1 0.0 7.6e-07 28.7 0.0 1.3 1 1 0 1 1 1 1 ORMDL family HSP70 PF00012.15 OAJ15403.1 - 0.057 11.3 0.0 0.072 10.9 0.0 1.0 1 0 0 1 1 1 0 Hsp70 protein UPF0016 PF01169.14 OAJ15404.1 - 8.4e-43 144.3 26.7 1.3e-22 79.7 5.9 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Ion_trans PF00520.26 OAJ15404.1 - 3.6e-05 23.0 0.9 3.6e-05 23.0 0.6 2.0 2 1 0 2 2 2 1 Ion transport protein MttA_Hcf106 PF02416.11 OAJ15404.1 - 0.17 11.0 1.1 17 4.6 0.0 2.5 2 0 0 2 2 2 0 mttA/Hcf106 family DUF2678 PF10856.3 OAJ15404.1 - 0.22 11.2 2.1 0.24 11.1 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) DUF308 PF03729.8 OAJ15404.1 - 4.6 7.3 16.6 0.6 10.1 0.2 3.3 4 1 0 4 4 4 0 Short repeat of unknown function (DUF308) DUF2376 PF09550.5 OAJ15405.1 - 0.22 11.7 0.8 0.33 11.1 0.5 1.3 1 0 0 1 1 1 0 Conserved hypothetical phage protein (DUF2376) EF-hand_1 PF00036.27 OAJ15406.1 - 3.1e-20 69.8 0.1 6e-06 25.1 0.0 4.4 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 OAJ15406.1 - 8.8e-19 65.6 0.1 4.4e-07 29.2 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 OAJ15406.1 - 1.3e-16 59.0 0.1 0.00058 19.0 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 OAJ15406.1 - 8e-15 54.7 0.0 6.9e-06 26.1 0.1 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 OAJ15406.1 - 8.7e-11 41.2 1.2 4.9e-06 26.0 0.0 3.6 3 2 2 5 5 5 4 EF-hand domain pair AT_hook PF02178.14 OAJ15426.1 - 7.1 6.6 10.2 0.5 10.2 1.7 3.0 2 0 0 2 2 2 0 AT hook motif Striatin PF08232.7 OAJ15429.1 - 0.00093 19.5 0.3 0.00093 19.5 0.2 2.4 3 0 0 3 3 3 1 Striatin family Mito_carr PF00153.22 OAJ15430.1 - 7e-66 217.9 0.6 4.6e-25 87.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rhomboid PF01694.17 OAJ15431.1 - 1.2e-06 28.6 13.8 0.00064 19.7 0.4 2.9 2 1 0 2 2 2 2 Rhomboid family DDE_3 PF13358.1 OAJ15432.1 - 2e-17 63.2 0.0 3.7e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 OAJ15432.1 - 0.0027 17.8 0.1 0.0027 17.8 0.1 1.6 2 0 0 2 2 2 1 Winged helix-turn helix DDE_1 PF03184.14 OAJ15432.1 - 0.015 14.4 0.0 0.064 12.3 0.0 1.8 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_33 PF13592.1 OAJ15432.1 - 0.076 12.5 0.2 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_IS630 PF01710.11 OAJ15432.1 - 0.09 12.4 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Transposase HTH_7 PF02796.10 OAJ15432.1 - 0.099 12.5 0.1 20 5.1 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Fimbrial_PilY2 PF14481.1 OAJ15433.1 - 0.041 13.2 1.8 0.042 13.2 0.2 1.8 2 0 0 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 rve PF00665.21 OAJ15434.1 - 1.2e-17 64.1 0.0 3.7e-17 62.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 OAJ15434.1 - 0.00029 20.3 0.0 0.0021 17.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain DUF2268 PF10026.4 OAJ15434.1 - 0.012 15.0 0.5 0.026 13.9 0.4 1.5 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) RVT_1 PF00078.22 OAJ15435.1 - 1e-17 64.1 0.0 2.5e-17 62.9 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA-synt_His PF13393.1 OAJ15454.1 - 0.0067 15.5 0.0 0.0083 15.2 0.0 1.0 1 0 0 1 1 1 1 Histidyl-tRNA synthetase TRIC PF05197.8 OAJ15456.1 - 0.13 11.6 0.0 0.55 9.6 0.0 1.9 2 0 0 2 2 2 0 TRIC channel Uso1_p115_C PF04871.8 OAJ15457.1 - 0.019 14.8 0.4 0.066 13.1 0.2 2.1 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region RVT_1 PF00078.22 OAJ15458.1 - 7.6e-19 67.9 0.0 1.8e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ15458.1 - 3.3e-13 49.7 0.0 9.9e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.15 OAJ15458.1 - 0.00038 20.3 0.0 0.001 18.9 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAJ15458.1 - 0.0071 16.8 0.0 0.025 15.0 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease DUF2072 PF09845.4 OAJ15459.1 - 0.22 11.4 0.0 0.44 10.4 0.0 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Pkinase PF00069.20 OAJ15477.1 - 2.1e-52 177.8 0.0 3.4e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ15477.1 - 4.4e-48 163.5 0.0 5.9e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ15477.1 - 0.013 15.2 1.2 0.049 13.3 0.0 2.6 2 2 0 2 2 2 0 Phosphotransferase enzyme family TLP-20 PF06088.6 OAJ15477.1 - 4.4 6.9 8.3 0.22 11.1 0.2 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PX PF00787.19 OAJ15478.1 - 1.6e-13 50.4 0.0 3.2e-13 49.4 0.0 1.5 1 1 0 1 1 1 1 PX domain SNARE PF05739.14 OAJ15478.1 - 4.9e-08 32.5 1.0 6.9e-08 32.0 0.7 1.2 1 0 0 1 1 1 1 SNARE domain Med3 PF11593.3 OAJ15478.1 - 0.3 10.2 7.9 0.45 9.7 5.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal adh_short PF00106.20 OAJ15479.1 - 8e-64 214.5 12.4 5.1e-32 111.1 2.8 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 OAJ15479.1 - 1.5e-28 99.7 7.6 6.3e-14 52.0 0.3 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 OAJ15479.1 - 1.1e-27 95.8 0.0 2.4e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 OAJ15479.1 - 2.2e-10 40.4 0.0 1.2e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 2-Hacid_dh_C PF02826.14 OAJ15479.1 - 7.7e-06 25.1 2.2 0.072 12.2 0.1 2.9 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 OAJ15479.1 - 0.00017 20.6 0.8 0.11 11.5 0.2 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 OAJ15479.1 - 0.0015 18.2 9.3 0.055 13.1 1.2 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF543 PF04418.7 OAJ15479.1 - 0.057 13.3 5.7 0.87 9.5 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF543) DUF3887 PF13026.1 OAJ15479.1 - 0.058 13.6 0.2 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) DHHA1 PF02272.14 OAJ15479.1 - 0.088 12.5 6.8 0.034 13.8 2.2 2.3 2 0 0 2 2 2 0 DHHA1 domain YjeF_N PF03853.10 OAJ15479.1 - 0.45 10.1 6.0 0.37 10.3 0.4 2.4 2 0 0 2 2 2 0 YjeF-related protein N-terminus Mur_ligase PF01225.20 OAJ15479.1 - 0.87 9.7 5.7 0.65 10.1 0.1 3.2 2 1 1 3 3 3 0 Mur ligase family, catalytic domain SUR7 PF06687.7 OAJ15481.1 - 6.3e-21 74.9 13.3 8.1e-21 74.5 9.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family JAB PF01398.16 OAJ15482.1 - 1.2e-14 53.9 0.0 2.1e-13 50.0 0.0 2.3 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 OAJ15482.1 - 2.2e-09 37.3 0.0 4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function MGC-24 PF05283.6 OAJ15482.1 - 0.21 11.3 10.8 0.44 10.3 7.5 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DUF4349 PF14257.1 OAJ15482.1 - 5.5 6.1 14.4 0.44 9.7 0.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) Bap31 PF05529.7 OAJ15484.1 - 6.9e-54 182.2 8.4 8.5e-54 181.9 5.8 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like GrpE PF01025.14 OAJ15484.1 - 0.2 11.2 4.5 0.11 12.0 1.1 1.8 2 0 0 2 2 2 0 GrpE HMG_box PF00505.14 OAJ15484.1 - 0.25 11.6 2.0 0.43 10.8 1.4 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box SeleniumBinding PF11524.3 OAJ15484.1 - 0.26 11.4 2.3 18 5.5 0.1 2.7 1 1 2 3 3 3 0 Selenium binding protein HDAC4_Gln PF12203.3 OAJ15484.1 - 0.92 9.4 7.9 0.56 10.1 1.6 2.5 1 1 2 3 3 3 0 Glutamine rich N terminal domain of histone deacetylase 4 LSM PF01423.17 OAJ15485.1 - 1.1e-20 72.9 0.3 1.3e-20 72.7 0.2 1.0 1 0 0 1 1 1 1 LSM domain Got1 PF04178.7 OAJ15501.1 - 1.3e-22 80.1 13.8 1.8e-22 79.6 9.5 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Acyl_transf_3 PF01757.17 OAJ15501.1 - 0.087 11.6 19.0 0.12 11.2 13.2 1.1 1 0 0 1 1 1 0 Acyltransferase family ATP_sub_h PF10775.4 OAJ15502.1 - 7.4e-23 80.0 1.0 1.1e-22 79.5 0.7 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 OAJ15502.1 - 0.0053 16.6 0.0 0.013 15.3 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase coupling factor 6 IATP PF04568.7 OAJ15503.1 - 2.2e-13 50.0 0.2 2.4e-13 49.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP YgaB PF14182.1 OAJ15503.1 - 0.1 12.8 2.8 0.13 12.4 1.9 1.1 1 0 0 1 1 1 0 YgaB-like protein PspB PF06667.7 OAJ15503.1 - 0.33 10.9 1.5 0.47 10.4 1.1 1.2 1 0 0 1 1 1 0 Phage shock protein B MULE PF10551.4 OAJ15505.1 - 2.5e-07 30.7 0.1 6.9e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.12 OAJ15505.1 - 0.0021 17.4 0.1 0.0063 15.9 0.1 1.7 1 0 0 1 1 1 1 SWIM zinc finger RTA1 PF04479.8 OAJ15506.1 - 2e-32 112.4 1.5 6.5e-25 87.9 0.1 2.1 2 0 0 2 2 2 2 RTA1 like protein adh_short PF00106.20 OAJ15507.1 - 0.098 12.5 0.5 0.62 9.9 0.3 2.2 1 1 0 1 1 1 0 short chain dehydrogenase SF3b10 PF07189.6 OAJ15510.1 - 4.8e-29 100.0 0.0 5.5e-29 99.8 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Metallophos PF00149.23 OAJ15511.1 - 0.0024 17.2 0.0 0.0028 17.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Band_3_cyto PF07565.8 OAJ15530.1 - 2.5 7.5 7.0 0.7 9.3 0.5 2.8 2 1 0 2 2 2 0 Band 3 cytoplasmic domain BTB PF00651.26 OAJ15531.1 - 1.7e-14 53.7 0.2 8e-10 38.6 0.0 3.6 3 0 0 3 3 3 3 BTB/POZ domain CAP_GLY PF01302.20 OAJ15531.1 - 4e-08 32.8 0.0 2.1e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 CAP-Gly domain Pkinase PF00069.20 OAJ15532.1 - 1e-74 250.9 0.0 1.4e-74 250.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ15532.1 - 1.3e-41 142.4 0.0 2.1e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 OAJ15532.1 - 5.2e-19 67.9 0.0 3.3e-08 33.3 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 OAJ15532.1 - 5e-09 35.5 0.0 6.6e-08 31.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 OAJ15532.1 - 0.058 12.4 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TP6A_N PF04406.9 OAJ15533.1 - 5.6e-14 51.5 0.0 1.6e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Type IIB DNA topoisomerase zf-UBR PF02207.15 OAJ15534.1 - 2.3e-13 49.6 11.4 2.3e-13 49.6 7.9 3.3 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 OAJ15534.1 - 0.00018 21.1 3.0 0.00018 21.1 2.1 3.2 3 0 0 3 3 3 1 PHD-finger RRM_1 PF00076.17 OAJ15535.1 - 0.00011 21.7 0.0 0.00023 20.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ15535.1 - 0.076 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) N2227 PF07942.7 OAJ15535.1 - 0.24 10.3 0.0 0.46 9.3 0.0 1.4 1 0 0 1 1 1 0 N2227-like protein PIF1 PF05970.9 OAJ15553.1 - 1.9e-06 27.1 0.0 6.1e-06 25.4 0.0 1.7 1 1 0 2 2 2 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ15553.1 - 4.8e-06 26.4 0.0 1.3e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Bunya_RdRp PF04196.7 OAJ15553.1 - 0.12 10.4 0.0 0.18 9.7 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase OmpH PF03938.9 OAJ15554.1 - 3.5 7.5 10.9 5.4 6.9 7.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Mnd1 PF03962.10 OAJ15554.1 - 6.9 6.2 9.3 10 5.7 6.4 1.3 1 0 0 1 1 1 0 Mnd1 family Presenilin PF01080.12 OAJ15554.1 - 9.6 4.9 5.6 14 4.4 3.9 1.2 1 0 0 1 1 1 0 Presenilin Dimer_Tnp_hAT PF05699.9 OAJ15555.1 - 2.5e-07 30.2 0.0 6.2e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Macoilin PF09726.4 OAJ15556.1 - 7.3 4.7 15.7 13 3.9 10.9 1.4 1 0 0 1 1 1 0 Transmembrane protein Dimer_Tnp_hAT PF05699.9 OAJ15558.1 - 1e-07 31.4 0.0 2.4e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Macoilin PF09726.4 OAJ15559.1 - 7.3 4.7 15.7 13 3.9 10.9 1.4 1 0 0 1 1 1 0 Transmembrane protein DUF4637 PF15470.1 OAJ15575.1 - 8.9 5.8 10.3 0.76 9.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Zn_clus PF00172.13 OAJ15576.1 - 2.3e-08 33.7 12.6 3.7e-08 33.1 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hid1 PF12722.2 OAJ15577.1 - 5.5e-104 348.6 0.0 1.1e-89 301.2 0.0 3.2 2 2 0 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 OAJ15577.1 - 1.9e-37 128.7 0.0 4.8e-36 124.1 0.0 2.4 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF2360 PF10152.4 OAJ15577.1 - 9.2 6.5 9.1 0.55 10.4 1.1 2.8 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF3446 PF11928.3 OAJ15578.1 - 0.14 12.3 1.9 0.17 12.1 0.4 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3446) Mpv17_PMP22 PF04117.7 OAJ15579.1 - 8.2e-25 86.2 1.0 1.2e-24 85.7 0.7 1.2 1 0 0 1 1 1 1 Mpv17 / PMP22 family C5-epim_C PF06662.8 OAJ15581.1 - 0.098 11.9 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus zf-4CXXC_R1 PF10497.4 OAJ15582.1 - 1.3e-05 25.2 10.5 2.7e-05 24.2 7.3 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 FYVE_2 PF02318.11 OAJ15582.1 - 0.22 11.4 2.9 0.48 10.3 2.0 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger SF-assemblin PF06705.6 OAJ15583.1 - 0.004 16.3 0.7 0.005 16.0 0.5 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Apolipoprotein PF01442.13 OAJ15583.1 - 0.017 14.6 0.1 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4366 PF14283.1 OAJ15583.1 - 0.076 12.4 1.5 0.093 12.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) SpoIIIAH PF12685.2 OAJ15583.1 - 0.16 11.4 3.7 0.22 10.9 2.5 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein ApoLp-III PF07464.6 OAJ15583.1 - 0.39 10.7 4.9 0.59 10.1 3.4 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Herpes_UL25 PF01499.11 OAJ15583.1 - 0.45 8.7 4.0 0.54 8.5 2.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Phasin PF05597.6 OAJ15583.1 - 0.49 10.1 5.7 14 5.4 3.9 2.1 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MRFAP1 PF15155.1 OAJ15583.1 - 2.6 8.4 6.6 0.96 9.7 2.3 1.6 1 1 1 2 2 2 0 MORF4 family-associated protein1 Flavoprotein PF02441.14 OAJ15606.1 - 6.5e-39 132.5 0.0 9e-39 132.1 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein Velvet PF11754.3 OAJ15607.1 - 1.2e-35 122.9 0.0 2.7e-35 121.8 0.0 1.5 1 0 0 1 1 1 1 Velvet factor DUF1983 PF09327.6 OAJ15608.1 - 0.16 11.9 0.3 0.63 10.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1983) Velvet PF11754.3 OAJ15609.1 - 2e-22 79.7 0.1 1.3e-21 77.1 0.1 1.8 1 1 0 1 1 1 1 Velvet factor ATXN-1_C PF12547.3 OAJ15610.1 - 0.054 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator TPR_11 PF13414.1 OAJ15611.1 - 3.2e-21 74.7 7.2 9.9e-08 31.5 0.0 3.7 3 1 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 OAJ15611.1 - 8.9e-19 66.2 2.5 1.4e-06 27.5 0.0 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ15611.1 - 6.8e-18 63.0 3.5 1.5e-05 24.5 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ15611.1 - 2.4e-13 50.3 9.1 2.1e-07 31.4 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ15611.1 - 4.2e-13 49.4 0.4 1.6e-05 25.1 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ15611.1 - 5.6e-12 45.4 11.0 6.3e-05 22.8 0.0 3.5 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ15611.1 - 3.3e-11 42.7 13.2 0.034 14.7 0.0 6.2 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ15611.1 - 4.6e-11 41.6 2.3 0.021 14.5 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ15611.1 - 1.7e-10 40.2 0.6 0.051 13.7 0.0 4.3 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ15611.1 - 1.9e-09 37.3 0.1 0.00026 21.2 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ15611.1 - 9.9e-07 28.5 0.1 0.00084 19.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ15611.1 - 1.1e-05 24.8 4.2 0.37 10.7 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ15611.1 - 3e-05 24.0 0.4 0.011 15.8 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 SPATA24 PF15175.1 OAJ15611.1 - 0.018 14.7 1.6 0.029 14.0 0.1 1.9 2 1 0 2 2 2 0 Spermatogenesis-associated protein 24 TPR_5 PF12688.2 OAJ15611.1 - 0.038 14.0 3.4 0.093 12.7 1.1 2.3 2 1 0 2 2 2 0 Tetratrico peptide repeat TPR_10 PF13374.1 OAJ15611.1 - 0.07 13.0 3.1 12 5.9 0.3 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF2580 PF10824.3 OAJ15611.1 - 2.9 8.3 9.0 0.65 10.3 2.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) BCDHK_Adom3 PF10436.4 OAJ15612.1 - 0.033 13.6 0.0 0.047 13.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase RTC4 PF14474.1 OAJ15613.1 - 2.5e-09 37.1 0.0 5.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain Med11 PF10280.4 OAJ15614.1 - 8.6e-05 22.5 0.0 9.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Mediator complex protein DUF4349 PF14257.1 OAJ15637.1 - 0.0079 15.4 1.4 0.0097 15.1 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) DUF2422 PF10337.4 OAJ15637.1 - 0.01 14.6 2.5 0.012 14.4 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF1465 PF07323.7 OAJ15637.1 - 0.13 11.8 1.4 0.14 11.7 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) His_Phos_1 PF00300.17 OAJ15637.1 - 0.15 12.1 1.2 0.22 11.5 0.8 1.4 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Nop14 PF04147.7 OAJ15637.1 - 0.19 9.6 18.7 0.21 9.4 13.0 1.0 1 0 0 1 1 1 0 Nop14-like family AAA_11 PF13086.1 OAJ15637.1 - 0.22 11.0 3.2 0.27 10.7 2.2 1.1 1 0 0 1 1 1 0 AAA domain RRN3 PF05327.6 OAJ15637.1 - 0.43 8.6 6.6 0.51 8.3 4.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NARP1 PF12569.3 OAJ15637.1 - 0.77 8.4 8.9 0.8 8.3 6.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cpn60_TCP1 PF00118.19 OAJ15638.1 - 5.7e-134 447.3 7.3 6.7e-134 447.1 5.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Gp49 PF05973.9 OAJ15638.1 - 0.046 13.7 0.1 9.9 6.2 0.0 3.3 3 0 0 3 3 3 0 Phage derived protein Gp49-like (DUF891) SLX9 PF15341.1 OAJ15639.1 - 1.5e-18 67.3 3.6 1.5e-18 67.3 2.5 1.6 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 Zn_clus PF00172.13 OAJ15640.1 - 5.9e-07 29.3 3.8 9.7e-07 28.6 2.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAJ15640.1 - 0.00077 18.4 0.0 0.0015 17.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Spt20 PF12090.3 OAJ15640.1 - 0.026 13.8 0.2 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 Spt20 family RAB3GAP2_N PF14655.1 OAJ15640.1 - 0.2 10.6 2.5 0.32 9.9 1.7 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Hid1 PF12722.2 OAJ15640.1 - 0.58 7.7 1.5 0.81 7.2 1.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Suf PF05843.9 OAJ15640.1 - 0.94 9.1 6.1 0.085 12.5 0.9 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TraI PF07057.6 OAJ15641.1 - 0.064 13.2 1.7 0.066 13.2 1.2 1.2 1 0 0 1 1 1 0 DNA helicase TraI Mito_carr PF00153.22 OAJ15642.1 - 7.3e-49 163.4 5.6 2.7e-16 59.0 0.0 3.9 4 0 0 4 4 4 3 Mitochondrial carrier protein Lipase_3 PF01764.20 OAJ15643.1 - 8.4e-14 51.3 0.0 2.1e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) PsaL PF02605.10 OAJ15643.1 - 0.0088 15.5 0.1 0.034 13.6 0.0 2.0 2 0 0 2 2 2 1 Photosystem I reaction centre subunit XI DPBB_1 PF03330.13 OAJ15644.1 - 1.7e-07 31.1 0.0 3.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ15644.1 - 0.00092 18.8 0.4 0.0016 18.1 0.2 1.3 1 0 0 1 1 1 1 Barwin family DUF2722 PF10846.3 OAJ15644.1 - 0.098 11.6 1.6 0.13 11.2 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DSBA PF01323.15 OAJ15646.1 - 2.4e-21 76.2 0.0 3e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF202 PF02656.10 OAJ15663.1 - 1.4e-06 28.3 10.5 1.1e-05 25.5 4.6 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF202) DsrH PF04077.7 OAJ15664.1 - 0.14 11.8 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 DsrH like protein EVE PF01878.13 OAJ15665.1 - 5.1e-44 149.7 0.0 8.7e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 EVE domain Nipped-B_C PF12830.2 OAJ15666.1 - 1.9e-47 161.3 3.3 3.7e-47 160.3 1.1 2.5 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 OAJ15666.1 - 6.7e-09 35.5 2.0 3.3e-07 30.1 0.1 3.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 OAJ15666.1 - 0.0059 16.4 0.4 0.046 13.5 0.1 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 OAJ15666.1 - 0.065 11.5 8.9 1.6 6.9 0.2 3.9 3 2 1 4 4 4 0 Adaptin N terminal region Peptidase_S26 PF10502.4 OAJ15667.1 - 1.4e-06 27.8 0.0 0.00012 21.5 0.0 3.0 3 1 0 3 3 3 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 OAJ15667.1 - 0.00019 21.0 0.0 0.0007 19.2 0.0 2.0 1 1 0 1 1 1 1 Peptidase S24-like Innate_immun PF12782.2 OAJ15668.1 - 0.014 14.6 8.5 0.03 13.5 5.9 1.5 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Cut8_C PF08559.5 OAJ15668.1 - 0.059 13.2 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Cut8 six-helix bundle SRA1 PF07304.6 OAJ15668.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.8 4 0 0 4 4 4 0 Steroid receptor RNA activator (SRA1) 6PF2K PF01591.13 OAJ15670.1 - 2.3e-63 213.2 0.0 3.2e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 OAJ15670.1 - 2.2e-21 76.6 0.0 5.3e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 OAJ15670.1 - 1.9e-05 24.5 0.0 3.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ15670.1 - 0.0019 18.9 0.7 0.02 15.6 0.0 2.8 3 1 1 4 4 4 1 AAA domain KTI12 PF08433.5 OAJ15670.1 - 0.0019 17.4 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 HMG_box PF00505.14 OAJ15671.1 - 1.4e-08 34.8 1.3 0.00012 22.3 0.2 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box QRPTase_C PF01729.14 OAJ15695.1 - 5.9e-42 143.0 0.5 2.5e-40 137.7 0.3 2.1 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 OAJ15695.1 - 6.1e-21 74.0 0.0 1.6e-20 72.6 0.0 1.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain SR-25 PF10500.4 OAJ15695.1 - 1.3 8.4 8.3 2 7.8 5.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Lung_7-TM_R PF06814.8 OAJ15696.1 - 5e-52 176.6 19.0 8.1e-52 175.9 13.1 1.3 1 1 0 1 1 1 1 Lung seven transmembrane receptor YlaC PF10777.4 OAJ15696.1 - 0.028 13.9 7.5 0.29 10.6 2.1 2.4 2 0 0 2 2 2 0 Inner membrane protein YlaC WD40 PF00400.27 OAJ15697.1 - 1.7e-19 68.8 11.4 3e-07 30.0 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Es2 PF09751.4 OAJ15698.1 - 7.6e-63 213.3 4.1 2.3e-62 211.7 2.8 1.9 1 1 0 1 1 1 1 Nuclear protein Es2 Proteasome PF00227.21 OAJ15699.1 - 4.2e-16 58.7 0.0 6.5e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit SAM_2 PF07647.12 OAJ15700.1 - 0.00052 19.8 0.0 0.00087 19.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) KilA-N PF04383.8 OAJ15700.1 - 0.00077 19.0 0.0 1.4 8.5 0.0 2.3 1 1 1 2 2 2 2 KilA-N domain LIP PF03583.9 OAJ15701.1 - 2e-41 142.0 0.2 3e-40 138.2 0.1 2.0 1 1 0 1 1 1 1 Secretory lipase Proteasome PF00227.21 OAJ15702.1 - 3e-43 147.3 0.0 4.3e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAJ15702.1 - 5.7e-09 35.1 1.3 1.8e-08 33.5 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature ADH_N PF08240.7 OAJ15722.1 - 4.6e-28 97.1 2.9 8e-28 96.3 2.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ15722.1 - 6.6e-19 67.7 0.1 1e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 OAJ15722.1 - 0.013 14.6 0.1 0.021 13.9 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NTP_transferase PF00483.18 OAJ15723.1 - 3.7e-08 32.9 0.0 5.6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 OAJ15723.1 - 0.00019 21.5 0.1 0.00067 19.7 0.0 1.9 2 0 0 2 2 2 1 MobA-like NTP transferase domain DUF364 PF04016.7 OAJ15723.1 - 0.15 11.4 0.1 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF364) PMT PF02366.13 OAJ15724.1 - 7.6e-72 241.6 12.6 7.6e-72 241.6 8.8 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 OAJ15724.1 - 5.6e-41 140.1 0.0 1.4e-40 138.8 0.0 1.7 1 0 0 1 1 1 1 MIR domain zf-RING_2 PF13639.1 OAJ15725.1 - 3.2e-11 42.8 10.2 2.7e-08 33.4 0.8 3.5 3 1 0 3 3 3 2 Ring finger domain zf-rbx1 PF12678.2 OAJ15725.1 - 3.1e-06 27.2 1.2 3.1e-06 27.2 0.8 2.7 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 OAJ15725.1 - 0.0001 21.8 5.6 0.01 15.4 0.5 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ15725.1 - 0.00014 21.4 4.4 0.015 15.0 0.3 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-Apc11 PF12861.2 OAJ15725.1 - 0.00017 21.3 2.0 0.0032 17.2 0.5 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 OAJ15725.1 - 0.00054 19.5 0.4 0.00054 19.5 0.3 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ15725.1 - 0.00099 19.0 0.8 0.00099 19.0 0.5 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 OAJ15725.1 - 0.44 10.6 5.9 0.23 11.5 1.8 2.3 2 1 0 2 2 2 0 RING-variant domain PHD PF00628.24 OAJ15725.1 - 1.7 8.3 12.4 0.68 9.6 1.5 3.5 4 0 0 4 4 4 0 PHD-finger zf-RING_4 PF14570.1 OAJ15725.1 - 2 8.0 4.6 31 4.2 0.1 3.3 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 OAJ15725.1 - 2.2 7.8 8.0 0.44 10.1 1.0 2.9 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger zf-RING-like PF08746.6 OAJ15725.1 - 2.7 8.0 5.1 7.3 6.6 0.1 2.6 2 0 0 2 2 2 0 RING-like domain SPA PF08616.5 OAJ15726.1 - 0.039 13.6 0.0 0.085 12.5 0.0 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis Avl9 PF09794.4 OAJ15726.1 - 0.18 10.2 0.0 1.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Transport protein Avl9 FA_hydroxylase PF04116.8 OAJ15727.1 - 1.6e-09 38.1 11.9 1.6e-09 38.1 8.2 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Fes1 PF08609.5 OAJ15729.1 - 1.4e-16 60.7 0.6 1.5e-14 54.1 0.3 3.0 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT PF02985.17 OAJ15729.1 - 5.9e-05 22.8 2.4 0.83 9.8 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 OAJ15729.1 - 0.00012 22.2 0.8 0.063 13.5 0.0 4.0 3 0 0 3 3 3 1 HEAT repeats Adaptin_N PF01602.15 OAJ15729.1 - 0.011 14.0 0.1 0.76 8.0 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.1 OAJ15729.1 - 3.6 8.1 9.1 22 5.7 0.0 4.6 5 0 0 5 5 5 0 HEAT-like repeat Thioredoxin PF00085.15 OAJ15730.1 - 9.2e-28 95.9 0.0 1.2e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 OAJ15730.1 - 6.4e-08 32.6 0.1 1.5e-05 25.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ15730.1 - 2.1e-07 31.1 0.0 1.1e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 OAJ15730.1 - 1.3e-06 28.3 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 OAJ15730.1 - 0.00011 21.7 0.3 0.0084 15.6 0.1 2.1 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 OAJ15730.1 - 0.00015 21.4 0.1 0.00051 19.7 0.0 1.6 1 1 1 2 2 2 1 AhpC/TSA family DIM1 PF02966.11 OAJ15730.1 - 0.00016 21.1 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_9 PF14595.1 OAJ15730.1 - 0.0011 18.5 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.6 OAJ15730.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE YfzA PF14118.1 OAJ15731.1 - 0.02 14.9 3.3 0.38 10.8 0.1 2.8 3 0 0 3 3 3 0 YfzA-like protein Methyltransf_16 PF10294.4 OAJ15751.1 - 3.2e-22 78.8 0.0 4.2e-10 39.3 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Cellulase PF00150.13 OAJ15752.1 - 0.012 14.8 0.0 0.087 12.0 0.0 2.0 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) HSP70 PF00012.15 OAJ15753.1 - 4.2e-29 100.9 0.1 6.1e-29 100.3 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein RNA_pol_I_A49 PF06870.7 OAJ15753.1 - 2.7e-08 32.8 0.0 4.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Peptidase_U40 PF10464.4 OAJ15753.1 - 0.065 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Peptidase U40 AMP-binding PF00501.23 OAJ15754.1 - 3.3e-72 243.1 0.0 5.1e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme DUF2462 PF09495.5 OAJ15755.1 - 2.1e-15 57.1 7.4 2.1e-15 57.1 5.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) RNR_inhib PF08591.5 OAJ15755.1 - 0.18 12.7 1.8 0.39 11.6 1.3 1.5 1 1 0 1 1 1 0 Ribonucleotide reductase inhibitor MSA-2c PF12238.3 OAJ15755.1 - 0.21 11.2 3.0 0.23 11.0 2.1 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c TauD PF02668.11 OAJ15757.1 - 2.6e-53 181.3 0.4 4.5e-53 180.5 0.0 1.6 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1455 PF07306.6 OAJ15759.1 - 0.074 13.1 0.9 0.22 11.5 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1455) SUZ-C PF12901.2 OAJ15760.1 - 0.11 12.1 0.5 0.29 10.8 0.3 1.6 1 0 0 1 1 1 0 SUZ-C motif Sigma70_ner PF04546.8 OAJ15760.1 - 0.14 11.7 1.6 0.17 11.5 0.8 1.4 1 1 1 2 2 2 0 Sigma-70, non-essential region Apc1 PF12859.2 OAJ15781.1 - 3.3e-12 46.5 0.0 1.5e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 OAJ15781.1 - 8.4e-05 22.5 12.6 0.11 12.7 0.0 6.1 7 0 0 7 7 7 3 Proteasome/cyclosome repeat RNA_pol_L_2 PF13656.1 OAJ15783.1 - 4.8e-24 83.6 0.0 6e-24 83.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 OAJ15783.1 - 3.7e-11 41.9 0.0 4.9e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Apc5 PF12862.2 OAJ15784.1 - 1.7e-14 53.3 1.6 4.8e-14 51.9 1.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 OAJ15784.1 - 0.038 13.9 5.6 1.6 8.7 0.9 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat UvsW PF11637.3 OAJ15784.1 - 0.049 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW TPR_2 PF07719.12 OAJ15784.1 - 2.4 8.3 4.3 16 5.7 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.27 OAJ15786.1 - 1.6e-22 78.4 16.5 1.1e-05 25.1 0.5 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 OAJ15786.1 - 0.09 12.4 0.0 3.2 7.4 0.0 2.6 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nucleo_P87 PF07267.6 OAJ15786.1 - 6.7 5.2 6.9 14 4.2 4.8 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PAP_assoc PF03828.14 OAJ15787.1 - 1e-16 60.6 0.2 1.9e-16 59.7 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 OAJ15787.1 - 1.6e-06 28.3 0.0 3.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain BRCA-2_OB1 PF09103.5 OAJ15806.1 - 3.9e-28 97.5 0.0 7.1e-28 96.6 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 OAJ15806.1 - 4.7e-07 29.5 0.3 7.8e-07 28.8 0.2 1.3 1 0 0 1 1 1 1 BRCA2, helical BRCA2 PF00634.13 OAJ15806.1 - 0.00014 21.0 0.1 0.00029 20.0 0.0 1.4 1 0 0 1 1 1 1 BRCA2 repeat 2-Hacid_dh_C PF02826.14 OAJ15807.1 - 1.1e-51 174.4 0.0 2e-51 173.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAJ15807.1 - 2.4e-34 117.6 0.0 3.3e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 OAJ15807.1 - 0.001 18.9 0.0 0.0028 17.4 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Aldedh PF00171.17 OAJ15808.1 - 1.5e-104 349.9 0.1 1.8e-104 349.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ERCC4 PF02732.10 OAJ15809.1 - 2.5e-24 85.6 0.0 5.5e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain SAM_PNT PF02198.11 OAJ15809.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Tfb2 PF03849.9 OAJ15810.1 - 2.6e-137 457.3 0.0 3.3e-137 457.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 OAJ15810.1 - 6.8e-06 25.8 0.0 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pyridox_oxase_2 PF12766.2 OAJ15812.1 - 5.6e-22 77.9 0.0 8.3e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase NIF PF03031.13 OAJ15813.1 - 1.9e-20 73.1 0.0 3.1e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 OAJ15813.1 - 0.0034 16.7 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family HhH-GPD PF00730.20 OAJ15814.1 - 7e-17 61.6 0.0 1.1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 OAJ15814.1 - 4.8e-08 32.2 0.0 1.6e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 OAJ15814.1 - 2.8 8.2 6.3 6 7.2 4.3 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III TAFII55_N PF04658.8 OAJ15815.1 - 2.9e-49 166.6 0.4 2.9e-49 166.6 0.2 1.9 2 0 0 2 2 2 1 TAFII55 protein conserved region AhpC-TSA_2 PF13911.1 OAJ15837.1 - 2.5e-15 56.3 0.0 3.5e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 OAJ15837.1 - 0.01 15.4 0.0 0.026 14.0 0.0 1.6 2 0 0 2 2 2 0 Redoxin NAD_binding_7 PF13241.1 OAJ15837.1 - 0.06 13.6 0.0 0.082 13.1 0.0 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding Hydrolase_4 PF12146.3 OAJ15837.1 - 0.092 12.6 0.0 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase RCC1 PF00415.13 OAJ15838.1 - 1.9e-31 108.0 6.2 3e-07 30.5 0.1 6.5 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ15838.1 - 9.8e-21 72.8 12.5 0.0003 20.3 0.0 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 OAJ15838.1 - 4.4e-10 39.0 11.2 4.4e-10 39.0 7.8 1.7 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 OAJ15838.1 - 0.00092 18.8 4.1 0.00092 18.8 2.9 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 OAJ15838.1 - 0.019 14.2 1.3 0.019 14.2 0.9 2.1 3 0 0 3 3 3 0 PHD-finger ADK_lid PF05191.9 OAJ15838.1 - 0.26 10.9 1.8 1.9 8.1 0.6 2.7 2 0 0 2 2 2 0 Adenylate kinase, active site lid C1_1 PF00130.17 OAJ15838.1 - 1.3 8.7 10.7 0.39 10.4 3.7 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CHCH PF06747.8 OAJ15839.1 - 4.4e-06 26.4 3.9 8e-06 25.6 2.7 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 OAJ15839.1 - 0.044 13.8 3.5 0.096 12.8 2.4 1.5 1 0 0 1 1 1 0 GCK domain DUF812 PF05667.6 OAJ15840.1 - 0.19 10.2 0.5 0.3 9.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) MAM33 PF02330.11 OAJ15841.1 - 5.9e-31 107.8 0.0 8.2e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial glycoprotein NESP55 PF06390.7 OAJ15841.1 - 2.9 7.1 13.9 0.18 11.1 6.0 1.5 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Pyridoxal_deC PF00282.14 OAJ15842.1 - 1.8e-22 79.3 0.0 2.5e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 OAJ15842.1 - 9e-11 41.1 0.0 1.8e-10 40.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 OAJ15842.1 - 0.0057 15.7 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family UPF0220 PF05255.6 OAJ15844.1 - 1.9e-50 170.3 0.0 2.5e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Glyco_transf_41 PF13844.1 OAJ15845.1 - 9.3e-97 323.9 0.4 1e-45 155.6 0.0 4.2 4 0 0 4 4 4 4 Glycosyl transferase family 41 TPR_11 PF13414.1 OAJ15845.1 - 4.1e-23 80.8 0.5 6e-09 35.4 0.0 4.8 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 OAJ15845.1 - 5.1e-19 67.0 0.0 5.6e-05 22.5 0.0 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ15845.1 - 7.9e-18 63.1 0.4 2.9e-05 23.9 0.0 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ15845.1 - 4.3e-14 51.2 0.0 0.0018 18.0 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ15845.1 - 2.5e-12 46.5 0.2 7.7e-05 22.5 0.0 4.9 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ15845.1 - 1.4e-11 43.2 0.0 0.0033 17.0 0.0 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ15845.1 - 4.5e-10 39.2 5.8 0.013 16.1 0.0 5.7 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ15845.1 - 7.1e-07 28.9 1.7 0.06 13.3 0.0 5.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ15845.1 - 2.1e-06 27.9 0.0 0.38 11.1 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ15845.1 - 0.00034 20.1 0.0 5.3 7.0 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ15845.1 - 0.019 15.4 0.0 65 4.3 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 OAJ15870.1 - 9.4e-57 192.1 0.0 1.4e-56 191.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ15870.1 - 7.9e-19 67.7 0.0 1.5e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 OAJ15870.1 - 0.0052 16.1 0.1 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 OAJ15870.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 OAJ15870.1 - 0.12 11.9 0.2 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Nop14 PF04147.7 OAJ15870.1 - 0.81 7.5 23.9 0.056 11.3 4.2 2.3 2 0 0 2 2 2 0 Nop14-like family VID27 PF08553.5 OAJ15870.1 - 7.4 4.6 6.0 19 3.3 4.1 1.6 1 0 0 1 1 1 0 VID27 cytoplasmic protein Exo_endo_phos_2 PF14529.1 OAJ15872.1 - 1e-17 63.8 0.0 1.9e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ15872.1 - 1.1e-05 25.5 0.5 2e-05 24.6 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 OAJ15872.1 - 2.9 7.9 7.4 0.21 11.5 1.3 2.1 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 OAJ15873.1 - 9.3e-23 80.7 0.0 1.5e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAJ15873.1 - 7.8e-16 58.6 0.0 1.3e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 RNase H CAF-1_p150 PF11600.3 OAJ15874.1 - 0.69 9.2 16.2 0.13 11.5 8.6 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal HAD PF12710.2 OAJ15875.1 - 0.076 13.1 0.0 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Topoisom_bac PF01131.15 OAJ15893.1 - 3.4e-51 174.3 0.0 4.3e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Pil1 PF13805.1 OAJ15894.1 - 8.6e-25 87.3 0.4 1.8e-24 86.3 0.1 1.6 1 1 0 1 1 1 1 Eisosome component PIL1 Lzipper-MIP1 PF14389.1 OAJ15894.1 - 0.12 12.4 6.5 2.2 8.4 1.7 2.7 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 GAS PF13851.1 OAJ15894.1 - 0.13 11.4 2.0 0.33 10.1 1.4 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Glyco_hydro_88 PF07470.8 OAJ15895.1 - 3.7e-15 55.8 0.6 7.8e-14 51.4 0.4 2.2 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 TTL PF03133.10 OAJ15897.1 - 6.6e-42 143.4 0.0 1.9e-28 99.2 0.0 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family CENP-B_dimeris PF09026.5 OAJ15897.1 - 0.00046 20.3 1.0 0.001 19.2 0.7 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Nro1 PF12753.2 OAJ15897.1 - 0.0047 15.9 4.9 0.007 15.3 3.4 1.2 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 Nucleoplasmin PF03066.10 OAJ15897.1 - 0.087 12.3 6.5 0.15 11.5 4.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 OAJ15897.1 - 0.92 8.1 7.9 1.5 7.4 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BSP_II PF05432.6 OAJ15897.1 - 6.8 5.8 10.2 13 4.9 7.1 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.7 OAJ15897.1 - 7.3 4.3 7.5 9.7 3.9 5.2 1.1 1 0 0 1 1 1 0 Nop14-like family Sec23_trunk PF04811.10 OAJ15898.1 - 1.3e-57 194.9 0.0 3.7e-51 173.8 0.0 2.1 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 OAJ15898.1 - 5.7e-22 77.0 0.0 9.8e-22 76.3 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 OAJ15898.1 - 1.3e-20 73.6 0.0 3.3e-20 72.4 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 OAJ15898.1 - 4.9e-16 57.9 5.5 9.5e-16 57.0 3.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 OAJ15898.1 - 0.0001 21.8 0.0 0.00024 20.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat LSM PF01423.17 OAJ15899.1 - 2e-12 46.4 0.0 2.4e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF4255 PF14065.1 OAJ15900.1 - 0.018 14.4 0.7 0.045 13.2 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) Topoisom_bac PF01131.15 OAJ15902.1 - 1.7e-16 60.0 0.0 2.1e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-CCHC PF00098.18 OAJ15902.1 - 2.3e-06 27.2 4.0 5.9e-06 25.9 2.8 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ15902.1 - 0.052 13.2 1.7 0.11 12.2 1.2 1.6 1 0 0 1 1 1 0 Zinc knuckle MbeD_MobD PF04899.7 OAJ15902.1 - 0.097 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 MbeD/MobD like zf-CCHC_4 PF14392.1 OAJ15902.1 - 0.31 10.7 1.1 0.92 9.2 0.8 1.8 1 0 0 1 1 1 0 Zinc knuckle Toprim PF01751.17 OAJ15903.1 - 2.6e-21 75.4 0.0 4.7e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Toprim domain Topoisom_bac PF01131.15 OAJ15903.1 - 2.9e-18 65.8 0.0 4.3e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase TIP41 PF04176.8 OAJ15903.1 - 0.076 12.2 0.1 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 TIP41-like family Y_phosphatase PF00102.22 OAJ15920.1 - 2.3e-29 102.3 0.0 5.2e-14 52.1 0.0 3.3 3 0 0 3 3 3 3 Protein-tyrosine phosphatase DSPc PF00782.15 OAJ15920.1 - 2.7e-06 27.0 0.0 5.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TAF4 PF05236.9 OAJ15921.1 - 5.2e-21 75.0 8.3 1.5e-16 60.4 0.1 3.7 1 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family DPBB_1 PF03330.13 OAJ15922.1 - 2.2e-05 24.3 0.2 8e-05 22.5 0.2 2.1 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel SAPS PF04499.10 OAJ15923.1 - 1.1e-145 486.0 0.0 4.2e-145 484.0 0.0 2.0 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein HORMA PF02301.13 OAJ15924.1 - 2e-37 128.7 0.7 4.9e-37 127.4 0.0 1.9 2 0 0 2 2 2 1 HORMA domain PHD PF00628.24 OAJ15924.1 - 5.9e-09 35.4 4.9 1e-08 34.7 3.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 OAJ15924.1 - 0.0011 18.2 2.0 0.0017 17.6 1.4 1.4 1 0 0 1 1 1 1 PHD-finger HTH_24 PF13412.1 OAJ15924.1 - 0.058 12.7 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Lactamase_B PF00753.22 OAJ15925.1 - 1.5e-09 37.8 4.7 3.4e-08 33.3 3.3 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAJ15925.1 - 0.0015 18.1 1.0 0.0032 17.0 0.7 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain WD40 PF00400.27 OAJ15926.1 - 8.4e-28 95.2 0.3 4.7e-10 38.9 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 OAJ15926.1 - 0.031 12.5 0.0 0.068 11.4 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain FA_hydroxylase PF04116.8 OAJ15927.1 - 5e-14 52.6 16.6 5e-14 52.6 11.5 2.0 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Peptidase_S8 PF00082.17 OAJ15942.1 - 1.5e-41 142.4 0.0 2.8e-41 141.5 0.0 1.4 1 1 0 1 1 1 1 Subtilase family PA PF02225.17 OAJ15942.1 - 4.5e-08 32.7 1.0 1e-07 31.5 0.1 2.0 2 0 0 2 2 2 1 PA domain DUF1034 PF06280.7 OAJ15942.1 - 4.2e-07 30.3 0.1 1.1e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) DUF2036 PF09724.4 OAJ15944.1 - 5.2e-50 170.4 0.0 7.7e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) RRM_1 PF00076.17 OAJ15946.1 - 9.6e-32 108.4 0.0 5.2e-16 58.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ15946.1 - 4.8e-23 80.9 0.0 2.3e-10 40.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ15946.1 - 2.7e-06 27.1 0.0 5.8e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ15946.1 - 0.0015 18.3 0.0 0.14 12.0 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif ArsA_ATPase PF02374.10 OAJ15948.1 - 2.8e-108 361.5 0.1 3.3e-108 361.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 OAJ15948.1 - 1.2e-13 50.9 0.2 1.8e-13 50.3 0.1 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 OAJ15948.1 - 6.4e-08 32.6 0.0 1.6e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 OAJ15948.1 - 1.7e-05 24.1 0.0 7.1e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 OAJ15948.1 - 0.00057 19.3 0.5 0.0046 16.4 0.1 2.2 1 1 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 OAJ15948.1 - 0.0042 16.2 0.0 0.0076 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 OAJ15948.1 - 0.0054 16.1 0.1 0.015 14.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain YhjQ PF06564.7 OAJ15948.1 - 0.0061 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 YhjQ protein AAA_18 PF13238.1 OAJ15948.1 - 0.019 15.2 0.0 0.058 13.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 OAJ15948.1 - 0.02 14.9 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 OAJ15948.1 - 0.026 14.2 0.1 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain PhoH PF02562.11 OAJ15948.1 - 0.053 12.7 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 OAJ15948.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 OAJ15948.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.17 OAJ15948.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Alba PF01918.16 OAJ15950.1 - 0.00026 20.5 0.0 0.00045 19.7 0.0 1.3 1 0 0 1 1 1 1 Alba Pkinase PF00069.20 OAJ15969.1 - 1.4e-73 247.2 0.0 1.7e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ15969.1 - 2.3e-40 138.2 0.0 2.9e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ15969.1 - 1.6e-06 27.2 0.0 2.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ15969.1 - 7.1e-06 25.2 0.0 1.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 OAJ15969.1 - 3.9e-05 23.0 0.0 6.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 OAJ15969.1 - 0.00094 18.9 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 OAJ15969.1 - 0.039 13.0 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pox_ser-thr_kin PF05445.6 OAJ15969.1 - 0.11 11.3 0.1 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 OAJ15969.1 - 0.14 11.7 0.1 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC_membrane PF00664.18 OAJ15970.1 - 4.9e-78 262.3 20.4 4e-46 157.6 4.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ15970.1 - 2.3e-50 170.4 0.1 2.9e-31 108.5 0.1 3.0 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAJ15970.1 - 1.6e-06 27.5 0.4 0.012 14.8 0.0 3.8 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 OAJ15970.1 - 0.00026 20.9 0.2 0.3 11.0 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 OAJ15970.1 - 0.00029 20.8 5.4 0.024 14.6 0.4 2.9 2 1 1 3 3 3 2 AAA ATPase domain DUF87 PF01935.12 OAJ15970.1 - 0.0013 18.6 0.8 0.29 10.9 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF258 PF03193.11 OAJ15970.1 - 0.0025 17.0 0.2 1 8.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 OAJ15970.1 - 0.003 17.0 0.8 3.2 7.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 OAJ15970.1 - 0.0034 17.2 0.4 0.48 10.2 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.1 OAJ15970.1 - 0.0043 16.4 0.2 4 6.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 OAJ15970.1 - 0.0047 15.8 0.0 0.47 9.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 OAJ15970.1 - 0.01 15.4 1.0 0.95 9.0 0.1 2.9 3 1 0 3 3 2 0 AAA domain AAA_21 PF13304.1 OAJ15970.1 - 0.031 14.2 0.0 8.2 6.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 OAJ15970.1 - 0.038 14.4 2.5 5.4 7.5 0.1 3.2 4 0 0 4 4 2 0 Miro-like protein ABC_ATPase PF09818.4 OAJ15970.1 - 0.13 10.8 0.5 0.8 8.2 0.1 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Helitron_like_N PF14214.1 OAJ15971.1 - 2.6e-33 115.2 0.2 4.1e-33 114.6 0.1 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 OAJ15972.1 - 6.3e-48 163.5 0.0 8.8e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ15972.1 - 1.2e-08 34.8 0.1 2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 OAJ15972.1 - 0.00069 19.8 0.0 0.0017 18.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ15972.1 - 0.00086 19.4 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAJ15972.1 - 0.00087 19.0 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 OAJ15972.1 - 0.00098 18.8 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 OAJ15972.1 - 0.0022 17.6 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 OAJ15972.1 - 0.011 15.7 0.0 6.7 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.4 OAJ15972.1 - 0.021 13.8 0.0 0.066 12.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 OAJ15972.1 - 0.027 13.3 0.0 0.055 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 OAJ15972.1 - 0.05 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NmrA PF05368.8 OAJ15973.1 - 1.9e-35 122.2 0.1 2.3e-35 121.9 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAJ15973.1 - 1.6e-14 54.3 0.1 3.3e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 OAJ15973.1 - 5.5e-05 23.1 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 OAJ15973.1 - 0.00035 19.3 0.0 0.00049 18.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 OAJ15973.1 - 0.0014 18.3 0.0 0.0025 17.4 0.0 1.5 1 1 0 1 1 1 1 KR domain CIA30 PF08547.7 OAJ15974.1 - 3.5e-18 65.9 0.0 3.1e-09 36.8 0.0 2.2 1 1 1 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Pol_alpha_B_N PF08418.5 OAJ15974.1 - 2.1 7.7 6.1 0.36 10.3 1.3 1.8 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal ANATO PF01821.13 OAJ15995.1 - 0.076 13.1 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 Anaphylotoxin-like domain DUF2439 PF10382.4 OAJ15996.1 - 6.1e-11 42.3 0.1 8.6e-11 41.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) TLP-20 PF06088.6 OAJ15997.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Mito_carr PF00153.22 OAJ15998.1 - 2.6e-54 180.8 9.1 2.5e-18 65.5 0.1 4.6 4 0 0 4 4 4 4 Mitochondrial carrier protein Thioredoxin PF00085.15 OAJ15999.1 - 7.5e-31 105.8 0.0 9.2e-31 105.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 OAJ15999.1 - 1.1e-08 35.1 0.2 9.5e-08 32.2 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAJ15999.1 - 3.3e-08 33.5 0.0 1.3e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 OAJ15999.1 - 2.5e-07 30.3 0.0 3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 OAJ15999.1 - 3.6e-06 26.5 0.0 5.7e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAJ15999.1 - 5.3e-05 22.8 0.0 6.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 OAJ15999.1 - 0.00055 19.9 0.0 0.00078 19.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 OAJ15999.1 - 0.0023 17.4 0.0 0.003 17.0 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF2847 PF11009.3 OAJ15999.1 - 0.0044 16.6 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Glutaredoxin PF00462.19 OAJ15999.1 - 0.0099 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_4 PF13462.1 OAJ15999.1 - 0.02 14.9 0.0 2.4 8.1 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin DIM1 PF02966.11 OAJ15999.1 - 0.023 14.2 0.0 0.025 14.1 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_3 PF13192.1 OAJ15999.1 - 0.024 14.4 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain WD40 PF00400.27 OAJ16000.1 - 1.6e-36 122.8 27.2 3.5e-09 36.2 0.3 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat Hira PF07569.6 OAJ16000.1 - 7.5e-32 110.3 0.0 1.4e-18 66.9 0.0 2.2 2 0 0 2 2 2 2 TUP1-like enhancer of split HIRA_B PF09453.5 OAJ16000.1 - 0.002 17.6 0.4 0.002 17.6 0.3 1.9 2 0 0 2 2 2 1 HIRA B motif DAO PF01266.19 OAJ16001.1 - 2.4e-36 125.4 0.1 3.1e-36 125.0 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAJ16001.1 - 5e-06 26.3 0.6 0.0016 18.2 0.0 2.4 1 1 1 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAJ16001.1 - 0.00071 19.5 0.2 0.0021 18.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAJ16001.1 - 0.0039 17.2 0.0 0.073 13.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ16001.1 - 0.067 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltrans_RNA PF04452.9 OAJ16001.1 - 0.072 12.1 0.1 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase DUF2423 PF10338.4 OAJ16002.1 - 5.2e-09 35.9 6.0 5.2e-09 35.9 4.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) CDC45 PF02724.9 OAJ16002.1 - 1.5 6.7 4.9 1.6 6.6 3.4 1.0 1 0 0 1 1 1 0 CDC45-like protein NUDIX PF00293.23 OAJ16003.1 - 2.1e-10 40.3 0.0 3.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Cupin_8 PF13621.1 OAJ16004.1 - 4.1e-18 65.7 0.0 7.7e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 OAJ16004.1 - 1.2e-17 64.2 0.1 1.1e-16 61.1 0.1 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase GPI PF06560.6 OAJ16004.1 - 0.02 13.8 0.0 0.043 12.8 0.0 1.5 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) PH PF00169.24 OAJ16005.1 - 3.7e-39 133.1 2.1 2.6e-19 69.3 0.2 3.3 3 0 0 3 3 3 3 PH domain PH_11 PF15413.1 OAJ16005.1 - 4.1e-18 65.6 8.9 1.7e-07 31.4 3.5 4.3 3 1 0 3 3 3 3 Pleckstrin homology domain PH_3 PF14593.1 OAJ16005.1 - 3.8e-16 58.8 2.1 9.7e-08 31.8 0.3 3.2 3 0 0 3 3 3 3 PH domain PH_8 PF15409.1 OAJ16005.1 - 1.4e-11 44.2 5.0 3.6e-07 30.1 0.9 3.0 3 0 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.1 OAJ16005.1 - 6.5e-07 29.5 7.7 0.00069 19.7 0.8 4.3 3 1 0 3 3 3 2 Pleckstrin homology domain Mcp5_PH PF12814.2 OAJ16005.1 - 1.4e-05 24.9 3.8 0.15 11.9 0.6 3.5 3 0 0 3 3 3 2 Meiotic cell cortex C-terminal pleckstrin homology PH_7 PF15408.1 OAJ16005.1 - 7.8e-05 22.5 0.9 0.00034 20.4 0.1 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.1 OAJ16005.1 - 1.4 8.4 16.2 0.17 11.3 0.2 4.5 3 1 0 4 4 4 0 Pleckstrin homology domain Got1 PF04178.7 OAJ16006.1 - 2.2e-20 72.8 13.5 2.5e-20 72.7 9.3 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family Fungal_trans PF04082.13 OAJ16028.1 - 7.9e-12 44.5 0.4 1.2e-11 44.0 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DER1 PF04511.10 OAJ16029.1 - 8.2e-07 28.7 5.0 3.7e-06 26.5 3.5 1.8 1 1 0 1 1 1 1 Der1-like family DUF1751 PF08551.5 OAJ16029.1 - 2.3e-05 24.6 1.3 3.5e-05 24.0 0.4 1.7 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 OAJ16029.1 - 2.8e-05 24.1 3.0 6.4e-05 23.0 2.0 1.8 1 1 0 1 1 1 1 Rhomboid family Oxidored_q2 PF00420.19 OAJ16029.1 - 3.2 7.4 6.7 0.64 9.6 1.2 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L HECT PF00632.20 OAJ16030.1 - 1.5e-78 264.1 0.0 2.1e-78 263.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.20 OAJ16031.1 - 5.6e-60 202.6 0.0 4.6e-33 114.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ16031.1 - 9.5e-20 70.7 0.0 2.8e-16 59.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 OAJ16031.1 - 0.021 13.8 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ16031.1 - 0.062 13.0 4.1 0.13 11.9 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family PPP4R2 PF09184.6 OAJ16031.1 - 0.31 10.5 4.3 0.7 9.3 3.0 1.5 1 0 0 1 1 1 0 PPP4R2 ELMO_CED12 PF04727.8 OAJ16032.1 - 1.2e-31 109.5 0.0 1.9e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 OAJ16032.1 - 3.4e-09 36.6 0.0 5.3e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) Drf_FH3 PF06367.11 OAJ16032.1 - 0.0014 18.0 0.1 0.0026 17.1 0.1 1.3 1 0 0 1 1 1 1 Diaphanous FH3 Domain V-ATPase_H_N PF03224.9 OAJ16032.1 - 0.0024 17.0 0.1 0.011 14.9 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H Herpes_V23 PF01802.12 OAJ16032.1 - 0.14 11.1 0.2 2.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus VP23 like capsid protein PHF5 PF03660.9 OAJ16033.1 - 2.9e-44 149.5 8.9 3.1e-44 149.4 6.1 1.0 1 0 0 1 1 1 1 PHF5-like protein UPF0547 PF10571.4 OAJ16033.1 - 0.052 13.2 2.1 0.052 13.2 1.5 3.3 5 0 0 5 5 5 0 Uncharacterised protein family UPF0547 DZR PF12773.2 OAJ16033.1 - 0.35 10.7 13.9 5 7.0 9.2 2.7 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.1 OAJ16033.1 - 0.45 10.2 11.4 2.8 7.7 0.2 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 OAJ16033.1 - 0.74 9.5 11.5 0.036 13.7 2.7 2.3 1 1 1 2 2 2 0 PHD-finger PolC_DP2 PF03833.8 OAJ16033.1 - 7.9 3.9 6.9 7.8 4.0 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Nbl1_Borealin_N PF10444.4 OAJ16048.1 - 2.3e-07 30.0 0.7 4e-07 29.3 0.5 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal POX PF07526.6 OAJ16048.1 - 1.8 8.8 4.6 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 Associated with HOX Haemolytic PF01809.13 OAJ16050.1 - 0.033 13.7 0.1 0.089 12.4 0.1 1.6 1 0 0 1 1 1 0 Haemolytic domain GTP_CH_N PF12471.3 OAJ16051.1 - 2.7e-86 288.1 0.0 4.5e-86 287.4 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 OAJ16051.1 - 6.3e-16 58.0 0.0 1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Arf PF00025.16 OAJ16052.1 - 1.3e-79 265.4 0.1 1.5e-79 265.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 OAJ16052.1 - 3.6e-14 52.3 0.0 4.4e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 OAJ16052.1 - 2.6e-13 49.7 0.0 2.8e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 OAJ16052.1 - 6e-13 48.2 1.1 1e-09 37.6 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 OAJ16052.1 - 3.1e-11 42.8 0.0 3.6e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 OAJ16052.1 - 3.3e-09 37.2 0.0 4.5e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 OAJ16052.1 - 5.5e-06 26.3 0.0 7.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAJ16052.1 - 0.0053 16.2 0.1 0.042 13.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 OAJ16052.1 - 0.0068 15.4 0.4 0.013 14.5 0.3 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 OAJ16052.1 - 0.077 12.8 0.1 0.14 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain Peptidase_S10 PF00450.17 OAJ16053.1 - 9.9e-100 334.5 0.0 1.3e-99 334.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 OAJ16053.1 - 0.0012 18.7 0.0 1.8 8.3 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Sugar_tr PF00083.19 OAJ16054.1 - 8e-27 93.9 8.9 4e-22 78.4 0.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ16054.1 - 1.5e-24 86.3 31.6 4.2e-17 61.8 9.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Pyr_redox PF00070.22 OAJ16055.1 - 3.2e-14 53.0 0.5 4.6e-09 36.5 0.4 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ16055.1 - 6.7e-09 35.9 0.0 0.0055 16.6 0.0 4.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_5 PF12695.2 OAJ16055.1 - 7.1e-05 22.5 0.3 0.17 11.6 0.1 2.6 2 0 0 2 2 2 2 Alpha/beta hydrolase family Pyr_redox_3 PF13738.1 OAJ16055.1 - 0.00025 21.1 1.4 0.9 9.5 0.0 3.6 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Myosin_N PF02736.14 OAJ16055.1 - 0.1 12.2 0.0 3.7 7.2 0.1 2.4 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain RP-C PF03428.8 OAJ16079.1 - 0.042 13.2 0.0 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 Replication protein C N-terminal domain HATPase_c PF02518.21 OAJ16081.1 - 3.8e-17 62.0 0.2 1e-16 60.6 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAJ16081.1 - 6.5e-17 61.5 0.0 4.7e-10 39.4 0.0 3.5 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.20 OAJ16081.1 - 3.2e-16 59.0 0.0 1.1e-15 57.4 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 OAJ16081.1 - 0.0011 19.1 0.1 0.038 14.1 0.0 2.8 2 0 0 2 2 2 1 GAF domain BolA PF01722.13 OAJ16082.1 - 8.4e-28 96.1 0.5 1.1e-27 95.7 0.3 1.1 1 0 0 1 1 1 1 BolA-like protein CNH PF00780.17 OAJ16083.1 - 2.2e-83 279.8 0.0 3.8e-83 279.0 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 OAJ16083.1 - 1.9e-45 154.1 0.0 4e-45 153.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 OAJ16083.1 - 1.4e-39 135.8 0.6 2.5e-39 135.0 0.4 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 OAJ16083.1 - 1.4e-11 43.9 0.0 2.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_10 PF15411.1 OAJ16083.1 - 0.042 14.0 0.1 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3577 PF12101.3 OAJ16084.1 - 2.5e-74 247.6 0.0 2.9e-39 134.1 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3577) AIG2_2 PF13772.1 OAJ16084.1 - 0.096 12.8 0.1 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 AIG2-like family HEAT_2 PF13646.1 OAJ16105.1 - 3.6e-27 94.4 35.2 3.7e-08 33.5 0.0 13.3 8 4 3 12 12 12 6 HEAT repeats HEAT PF02985.17 OAJ16105.1 - 1.8e-24 83.6 22.4 0.01 15.8 0.0 15.7 18 0 0 18 18 18 7 HEAT repeat HEAT_EZ PF13513.1 OAJ16105.1 - 7.7e-17 61.2 46.2 0.0011 19.3 0.0 16.9 15 2 4 19 19 19 6 HEAT-like repeat Vac14_Fab1_bd PF12755.2 OAJ16105.1 - 2.3e-09 37.4 0.0 0.011 16.0 0.0 6.0 4 2 1 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 OAJ16105.1 - 1.9e-08 33.9 0.1 3e-05 23.4 0.0 4.3 3 1 1 4 4 4 1 CLASP N terminal Cohesin_HEAT PF12765.2 OAJ16105.1 - 1.9e-05 24.4 3.4 0.25 11.3 0.0 5.4 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion UME PF08064.8 OAJ16105.1 - 0.00018 21.4 0.2 3.6 7.5 0.0 5.8 5 1 2 7 7 7 1 UME (NUC010) domain Cnd3 PF12719.2 OAJ16105.1 - 0.0044 16.0 0.2 5.9 5.7 0.0 3.5 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain Ecm29 PF13001.2 OAJ16105.1 - 0.012 14.0 0.6 0.43 9.0 0.0 3.1 2 1 1 3 3 3 0 Proteasome stabiliser Cnd1 PF12717.2 OAJ16105.1 - 0.06 13.1 0.0 2.2e+02 1.5 0.0 5.3 3 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 VID27 PF08553.5 OAJ16106.1 - 9.6e-244 811.2 12.6 3.7e-165 551.3 0.4 2.1 2 0 0 2 2 2 2 VID27 cytoplasmic protein VID27 PF08553.5 OAJ16107.1 - 5.6e-37 127.4 1.3 7.1e-37 127.0 0.9 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein SMN PF06003.7 OAJ16107.1 - 0.09 11.8 2.4 0.047 12.7 0.3 1.5 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) PAS_9 PF13426.1 OAJ16109.1 - 3.1e-26 91.7 0.0 1.4e-15 57.5 0.0 3.3 3 0 0 3 3 3 2 PAS domain PAS PF00989.19 OAJ16109.1 - 4.6e-16 58.6 0.0 3.3e-09 36.5 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS_3 PF08447.6 OAJ16109.1 - 2.5e-12 46.7 0.0 4.7e-07 29.8 0.0 3.8 2 1 1 3 3 3 2 PAS fold PAS_4 PF08448.5 OAJ16109.1 - 9.5e-09 35.2 0.0 0.0013 18.6 0.0 4.8 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.1 OAJ16109.1 - 1.8e-05 24.4 0.0 0.0034 17.1 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.1 OAJ16109.1 - 0.00028 20.8 0.0 0.0013 18.6 0.0 2.2 1 1 0 1 1 1 1 PAS domain SH2_2 PF14633.1 OAJ16133.1 - 4.9e-66 221.9 0.1 1.2e-65 220.6 0.1 1.7 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 OAJ16133.1 - 1.3e-23 83.2 5.4 1.2e-22 80.1 0.0 3.8 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 OAJ16133.1 - 7e-23 80.7 0.0 1.4e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 OAJ16133.1 - 8.9e-20 70.7 1.3 4.5e-13 49.0 0.0 2.9 3 0 0 3 3 3 2 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 OAJ16133.1 - 1.3e-17 63.7 26.9 1.3e-17 63.7 18.7 6.6 5 1 2 7 7 7 2 Acidic N-terminal SPT6 SH2 PF00017.19 OAJ16133.1 - 0.00045 19.9 0.0 0.00094 18.9 0.0 1.6 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 OAJ16133.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif dCMP_cyt_deam_1 PF00383.17 OAJ16135.1 - 4.9e-20 71.0 0.0 8.3e-20 70.3 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 OAJ16135.1 - 1.9e-05 24.5 0.0 3.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Bd3614-like deaminase Cyt-b5 PF00173.23 OAJ16136.1 - 2.9e-26 91.0 0.0 3.7e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MULE PF10551.4 OAJ16137.1 - 2.9e-18 65.8 0.0 6.6e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.10 OAJ16137.1 - 1.4e-09 37.3 0.0 3.5e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.13 OAJ16137.1 - 1.1e-06 27.5 0.0 1.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Glyco_transf_22 PF03901.12 OAJ16139.1 - 6e-83 279.1 12.4 2.3e-64 217.9 4.5 2.8 2 1 0 2 2 2 2 Alg9-like mannosyltransferase family PMT_2 PF13231.1 OAJ16139.1 - 1.4e-07 31.5 4.9 4.5e-07 29.9 3.4 1.8 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase WD40 PF00400.27 OAJ16140.1 - 1.7e-14 53.0 0.5 2.9e-08 33.2 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Y_phosphatase2 PF03162.8 OAJ16141.1 - 1.2e-56 190.6 0.0 1.8e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 OAJ16141.1 - 9.7e-08 32.4 0.0 2.7e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 OAJ16141.1 - 0.00084 18.7 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 OAJ16141.1 - 0.0077 15.8 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Cellulase PF00150.13 OAJ16142.1 - 6.8e-16 58.2 0.4 1e-15 57.7 0.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BRCT PF00533.21 OAJ16143.1 - 1.1e-07 31.9 0.0 2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 OAJ16143.1 - 2.2e-06 27.4 0.0 5.4e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.3 OAJ16143.1 - 0.00013 21.6 0.0 0.00029 20.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.16 OAJ16143.1 - 0.00067 19.7 0.1 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain Myc_N PF01056.13 OAJ16143.1 - 0.014 14.5 5.5 0.025 13.7 3.8 1.4 1 0 0 1 1 1 0 Myc amino-terminal region ADH_zinc_N PF00107.21 OAJ16164.1 - 4.7e-12 45.5 0.1 1.5e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ16164.1 - 4.2e-10 39.3 1.1 7.7e-09 35.2 0.7 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 OAJ16164.1 - 1.5e-05 25.8 0.0 3.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HsbA PF12296.3 OAJ16165.1 - 0.00095 19.0 3.2 0.0017 18.1 2.2 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A SNF2_N PF00176.18 OAJ16166.1 - 1.2e-76 257.4 0.1 2.3e-76 256.4 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.8 OAJ16166.1 - 7.3e-19 67.3 9.8 3.1e-18 65.3 6.8 2.2 1 0 0 1 1 1 1 HSA Helicase_C PF00271.26 OAJ16166.1 - 3e-18 65.4 0.0 6.3e-17 61.2 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.20 OAJ16166.1 - 7.3e-17 61.0 0.4 1.8e-16 59.7 0.3 1.8 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 OAJ16166.1 - 1.4e-14 53.9 1.1 1.4e-14 53.9 0.8 3.4 2 1 1 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 OAJ16166.1 - 5.1e-11 41.7 2.9 1.4e-10 40.4 2.0 1.8 1 0 0 1 1 1 1 QLQ DUF3085 PF11284.3 OAJ16166.1 - 0.06 13.5 0.1 16 5.7 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3085) Cpn60_TCP1 PF00118.19 OAJ16167.1 - 1.5e-141 472.3 11.9 1.8e-141 472.1 8.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 OAJ16167.1 - 0.00095 18.4 0.1 0.004 16.4 0.0 2.1 2 0 0 2 2 2 1 Telomere recombination Abhydrolase_3 PF07859.8 OAJ16168.1 - 2.6e-06 27.1 0.4 6.4e-06 25.8 0.3 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ16168.1 - 0.00038 20.2 0.0 0.00061 19.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ16168.1 - 0.00082 19.3 3.6 0.0012 18.8 2.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 OAJ16168.1 - 0.062 12.7 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) 4HBT_2 PF13279.1 OAJ16170.1 - 6.1e-05 23.4 0.0 0.00012 22.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily EI24 PF07264.6 OAJ16171.1 - 6e-24 84.6 13.1 9.3e-24 84.0 9.1 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Abhydrolase_5 PF12695.2 OAJ16172.1 - 0.0026 17.5 0.1 0.023 14.4 0.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 OAJ16172.1 - 0.091 11.6 0.0 0.21 10.4 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Herpes_gE PF02480.11 OAJ16172.1 - 0.12 10.5 0.0 0.22 9.7 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2919 PF11143.3 OAJ16172.1 - 0.24 11.2 0.3 0.48 10.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) DAP PF15228.1 OAJ16173.1 - 0.13 13.0 0.3 0.13 13.0 0.2 2.8 3 1 0 3 3 3 0 Death-associated protein SelP_N PF04592.9 OAJ16173.1 - 1.4 8.2 4.7 2 7.7 3.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Bromodomain PF00439.20 OAJ16193.1 - 6.5e-18 64.4 0.0 1.3e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Cut8_N PF14482.1 OAJ16193.1 - 1.3 9.1 8.0 16 5.5 1.0 4.0 3 0 0 3 3 3 0 Cut8 proteasome-binding domain BC10 PF06726.7 OAJ16194.1 - 1e-11 44.6 9.2 1.8e-11 43.8 6.4 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 RRXRR PF14239.1 OAJ16194.1 - 0.24 10.8 2.4 0.39 10.1 1.7 1.2 1 0 0 1 1 1 0 RRXRR protein FlxA PF14282.1 OAJ16194.1 - 0.64 9.9 13.2 1.8 8.5 9.1 1.8 1 0 0 1 1 1 0 FlxA-like protein SWIB PF02201.13 OAJ16195.1 - 5.3e-28 96.5 0.1 8.2e-28 95.9 0.1 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 OAJ16195.1 - 7.2e-07 28.8 1.6 5.6e-05 22.8 0.4 2.9 3 0 0 3 3 3 1 DEK C terminal domain TFIIF_alpha PF05793.7 OAJ16195.1 - 3.8 5.7 11.3 0.26 9.6 3.0 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LSM PF01423.17 OAJ16196.1 - 7.1e-16 57.5 0.1 9.8e-16 57.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain MRJP PF03022.11 OAJ16196.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.0 1 0 0 1 1 1 0 Major royal jelly protein WD40 PF00400.27 OAJ16197.1 - 1.5e-18 65.8 5.6 1.3e-07 31.2 0.1 5.9 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF3639 PF12341.3 OAJ16197.1 - 0.0017 18.2 2.4 0.0067 16.3 0.7 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) BBS2_Mid PF14783.1 OAJ16197.1 - 0.2 11.4 0.0 0.68 9.7 0.0 1.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Piwi PF02171.12 OAJ16198.1 - 1.2e-77 260.8 0.0 1.8e-77 260.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 OAJ16198.1 - 2e-19 69.2 0.0 3.9e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 OAJ16198.1 - 1.3e-13 50.0 0.0 3e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Alpha-amyl_C2 PF07821.7 OAJ16198.1 - 0.081 12.8 0.0 2.9 7.8 0.0 2.5 2 0 0 2 2 2 0 Alpha-amylase C-terminal beta-sheet domain Ferrochelatase PF00762.14 OAJ16199.1 - 4.2e-104 347.9 0.0 5e-104 347.6 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.12 OAJ16199.1 - 0.016 15.3 0.0 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 CbiX Malic_M PF03949.10 OAJ16200.1 - 1.8e-84 283.3 0.0 2.4e-84 282.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 OAJ16200.1 - 1.6e-63 213.5 0.0 3e-63 212.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain UMP1 PF05348.6 OAJ16218.1 - 3.9e-18 65.6 0.7 4.8e-18 65.3 0.5 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 BIR PF00653.16 OAJ16219.1 - 1.5e-26 92.5 1.9 7.2e-19 67.9 1.2 2.9 2 1 0 2 2 2 2 Inhibitor of Apoptosis domain Tfb4 PF03850.9 OAJ16219.1 - 1 8.5 6.3 2.2 7.4 4.4 1.5 1 0 0 1 1 1 0 Transcription factor Tfb4 Mem_trans PF03547.13 OAJ16219.1 - 5.5 5.1 4.5 7.6 4.7 3.1 1.3 1 0 0 1 1 1 0 Membrane transport protein Ycf1 PF05758.7 OAJ16219.1 - 5.6 4.5 20.0 9.3 3.8 13.9 1.3 1 0 0 1 1 1 0 Ycf1 HALZ PF02183.13 OAJ16220.1 - 0.17 11.6 0.9 0.4 10.4 0.6 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 OAJ16220.1 - 1.2 9.0 7.1 0.43 10.4 2.0 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Pectate_lyase_3 PF12708.2 OAJ16221.1 - 9.6e-68 228.6 5.4 3.3e-48 164.7 2.7 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 OAJ16221.1 - 2.7e-05 23.5 1.7 0.055 12.9 0.0 3.4 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 OAJ16221.1 - 0.0032 17.2 2.7 0.01 15.5 1.4 2.1 1 1 0 1 1 1 1 Right handed beta helix region Ldh_1_N PF00056.18 OAJ16221.1 - 0.16 11.7 0.0 0.46 10.2 0.0 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain DUF572 PF04502.8 OAJ16225.1 - 1.9e-57 194.9 2.4 2.4e-57 194.6 1.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF3052 PF11253.3 OAJ16225.1 - 0.0043 16.6 0.1 0.0071 15.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3052) DUF1315 PF07023.7 OAJ16225.1 - 0.026 14.3 0.1 0.068 13.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1315) DUF1191 PF06697.7 OAJ16226.1 - 0.0019 17.0 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 OAJ16226.1 - 0.0073 16.6 0.3 0.017 15.4 0.0 1.7 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 OAJ16226.1 - 0.14 11.8 0.8 0.35 10.5 0.6 1.6 1 0 0 1 1 1 0 Syndecan domain YajC PF02699.10 OAJ16226.1 - 0.23 11.1 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit DUF4098 PF13345.1 OAJ16252.1 - 2.2e-05 24.2 0.2 0.0017 18.2 0.0 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4098) PBP1_TM PF14812.1 OAJ16252.1 - 0.52 10.6 13.0 15 5.9 0.5 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AATase PF07247.7 OAJ16253.1 - 0.026 13.1 0.0 0.058 11.9 0.0 1.4 1 1 0 1 1 1 0 Alcohol acetyltransferase TP_methylase PF00590.15 OAJ16254.1 - 6.8e-33 114.1 0.2 1.3e-32 113.2 0.1 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 OAJ16254.1 - 1.6e-07 31.5 0.0 0.00031 20.9 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 OAJ16254.1 - 5e-07 28.5 0.1 1e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.1 OAJ16254.1 - 3e-06 26.4 0.0 0.0034 16.6 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Tetraspannin PF00335.15 OAJ16255.1 - 0.0029 16.9 10.3 0.0029 16.9 7.2 1.6 1 1 0 1 1 1 1 Tetraspanin family ApoO PF09769.4 OAJ16255.1 - 0.012 15.2 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 Apolipoprotein O TMEM51 PF15345.1 OAJ16255.1 - 0.016 14.8 0.4 0.47 10.0 0.3 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 DUF3481 PF11980.3 OAJ16255.1 - 0.22 11.3 0.1 0.22 11.3 0.1 3.0 1 1 3 4 4 4 0 Domain of unknown function (DUF3481) Cyto_ox_2 PF02322.10 OAJ16255.1 - 2.3 7.3 18.0 3.3 6.8 12.5 1.2 1 0 0 1 1 1 0 Cytochrome oxidase subunit II DUF3302 PF11742.3 OAJ16255.1 - 3 7.7 10.2 3.2 7.6 1.6 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3302) EphA2_TM PF14575.1 OAJ16255.1 - 6.9 7.1 0.0 6.9 7.1 0.0 3.5 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF2157 PF09925.4 OAJ16255.1 - 9.3 5.8 17.3 12 5.4 0.5 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) HEAT_2 PF13646.1 OAJ16256.1 - 0.015 15.6 1.2 0.015 15.6 0.8 2.2 2 1 0 2 2 2 0 HEAT repeats MscS_TM PF12794.2 OAJ16256.1 - 0.49 8.9 2.0 0.72 8.4 1.4 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Tropomyosin_1 PF12718.2 OAJ16257.1 - 3.5e-44 150.1 30.5 4.2e-44 149.8 21.1 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 OAJ16257.1 - 1.6e-12 47.0 30.8 6.9e-07 28.5 7.4 2.1 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.4 OAJ16257.1 - 0.0002 21.2 31.7 0.0019 18.0 6.0 3.2 1 1 2 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.14 OAJ16257.1 - 0.0005 19.6 33.1 0.0097 15.4 12.1 2.0 1 1 1 2 2 2 2 Ezrin/radixin/moesin family TelA PF05816.6 OAJ16257.1 - 0.0009 18.0 3.0 0.0009 18.0 2.1 2.0 1 1 1 2 2 2 1 Toxic anion resistance protein (TelA) BLOC1_2 PF10046.4 OAJ16257.1 - 0.0027 17.7 14.9 0.013 15.6 1.2 3.2 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 RasGAP_C PF03836.10 OAJ16257.1 - 0.0071 16.0 12.0 0.0099 15.5 8.3 1.3 1 0 0 1 1 1 1 RasGAP C-terminus FliD_C PF07195.7 OAJ16257.1 - 0.021 14.1 12.4 0.1 11.8 3.0 2.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus TPR_MLP1_2 PF07926.7 OAJ16257.1 - 0.023 14.4 29.4 0.42 10.3 13.2 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 OAJ16257.1 - 0.027 14.3 26.8 0.48 10.3 5.0 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Myosin_tail_1 PF01576.14 OAJ16257.1 - 0.038 11.7 30.3 0.046 11.4 21.0 1.1 1 0 0 1 1 1 0 Myosin tail Dynamitin PF04912.9 OAJ16257.1 - 0.045 12.5 14.5 0.08 11.7 10.1 1.6 1 1 0 1 1 1 0 Dynamitin DUF4200 PF13863.1 OAJ16257.1 - 0.06 13.2 29.0 0.18 11.7 5.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Filament PF00038.16 OAJ16257.1 - 0.071 12.5 26.0 0.25 10.7 8.3 2.0 1 1 1 2 2 2 0 Intermediate filament protein EzrA PF06160.7 OAJ16257.1 - 0.12 10.5 19.3 0.034 12.3 4.2 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA V_ATPase_I PF01496.14 OAJ16257.1 - 0.13 10.0 14.5 0.16 9.8 10.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF919 PF06034.6 OAJ16257.1 - 0.16 11.5 7.4 0.13 11.8 0.4 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) HrpB7 PF09486.5 OAJ16257.1 - 0.18 11.7 18.0 0.28 11.0 4.3 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF641 PF04859.7 OAJ16257.1 - 0.24 11.1 17.8 0.075 12.7 3.2 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) APG6 PF04111.7 OAJ16257.1 - 0.26 10.2 29.7 1 8.3 9.4 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF3584 PF12128.3 OAJ16257.1 - 0.27 8.5 25.6 0.35 8.1 17.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF972 PF06156.8 OAJ16257.1 - 0.27 11.5 21.0 0.88 9.9 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HisKA_3 PF07730.8 OAJ16257.1 - 0.3 11.4 12.4 4.6 7.6 2.9 3.9 1 1 2 3 3 3 0 Histidine kinase Fib_alpha PF08702.5 OAJ16257.1 - 0.31 11.1 12.4 2 8.5 2.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.3 OAJ16257.1 - 0.34 10.1 20.0 1.4 8.0 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) LRS4 PF10422.4 OAJ16257.1 - 0.43 9.9 16.4 0.54 9.5 11.3 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 TMF_DNA_bd PF12329.3 OAJ16257.1 - 0.46 10.3 34.0 0.59 9.9 8.2 3.6 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Mod_r PF07200.8 OAJ16257.1 - 0.46 10.3 22.0 0.29 11.0 6.6 2.6 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.1 OAJ16257.1 - 0.5 9.5 25.7 1.3 8.1 13.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.15 OAJ16257.1 - 0.52 10.1 27.0 2.4 7.9 2.2 3.8 1 1 1 3 3 3 0 Prefoldin subunit AAA_13 PF13166.1 OAJ16257.1 - 0.65 8.3 19.7 2 6.7 12.9 1.7 1 1 0 1 1 1 0 AAA domain Striatin PF08232.7 OAJ16257.1 - 0.89 9.8 22.1 0.22 11.8 9.1 2.1 1 1 1 2 2 2 0 Striatin family CDC37_N PF03234.9 OAJ16257.1 - 0.94 9.7 18.6 1.3 9.3 12.9 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF1664 PF07889.7 OAJ16257.1 - 1.1 9.1 10.8 6 6.6 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.1 OAJ16257.1 - 1.1 8.1 18.8 1.8 7.4 13.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Laminin_II PF06009.7 OAJ16257.1 - 1.3 8.7 15.2 2.4 7.9 3.1 2.6 1 1 1 2 2 2 0 Laminin Domain II IpaD PF06511.6 OAJ16257.1 - 1.3 7.9 7.2 2 7.3 5.0 1.3 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD Spc7 PF08317.6 OAJ16257.1 - 1.4 7.5 24.3 1 7.9 6.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Occludin_ELL PF07303.8 OAJ16257.1 - 1.5 9.5 17.0 12 6.6 3.9 3.6 1 1 2 3 3 3 0 Occludin homology domain Sec20 PF03908.8 OAJ16257.1 - 1.5 8.5 5.5 0.54 10.0 1.3 2.1 2 0 0 2 2 2 0 Sec20 Flagellin_N PF00669.15 OAJ16257.1 - 1.6 8.5 6.8 0.6 9.8 0.7 2.4 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region Fmp27_WPPW PF10359.4 OAJ16257.1 - 1.7 6.9 22.6 2.7 6.3 7.1 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Reo_sigmaC PF04582.7 OAJ16257.1 - 1.8 7.6 5.8 6.6 5.8 1.7 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein SlyX PF04102.7 OAJ16257.1 - 1.9 8.8 14.0 1 9.7 2.0 3.2 1 1 2 3 3 2 0 SlyX CCDC155 PF14662.1 OAJ16257.1 - 2 7.9 29.5 0.66 9.5 6.2 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF812 PF05667.6 OAJ16257.1 - 2.1 6.7 24.9 0.94 7.9 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF2959 PF11172.3 OAJ16257.1 - 2.1 8.0 13.3 0.75 9.5 0.8 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2959) IncA PF04156.9 OAJ16257.1 - 2.3 7.7 28.3 95 2.5 19.5 2.1 1 1 0 1 1 1 0 IncA protein Cortex-I_coil PF09304.5 OAJ16257.1 - 2.4 8.2 25.2 0.4 10.7 6.4 2.7 2 1 0 2 2 2 0 Cortexillin I, coiled coil Laminin_I PF06008.9 OAJ16257.1 - 2.4 7.3 23.1 1.8 7.8 11.4 2.4 1 1 1 2 2 2 0 Laminin Domain I Ax_dynein_light PF10211.4 OAJ16257.1 - 2.6 7.8 22.5 0.74 9.6 6.0 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain Allexi_40kDa PF05549.6 OAJ16257.1 - 2.7 7.2 13.0 3.4 6.8 4.5 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF730 PF05325.6 OAJ16257.1 - 2.7 7.8 11.6 1.9 8.2 2.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF730) THOC7 PF05615.8 OAJ16257.1 - 3 8.1 23.3 0.29 11.4 5.9 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 Kinetocho_Slk19 PF12709.2 OAJ16257.1 - 3.5 7.7 20.8 4.4 7.4 1.6 3.1 1 1 1 3 3 2 0 Central kinetochore-associated DUF4140 PF13600.1 OAJ16257.1 - 3.8 8.0 23.8 5.4 7.5 2.7 3.6 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) CASP_C PF08172.7 OAJ16257.1 - 4.3 6.2 19.5 0.37 9.7 1.0 2.2 1 1 1 2 2 2 0 CASP C terminal Atg14 PF10186.4 OAJ16257.1 - 4.5 6.1 23.6 0.15 10.9 4.4 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Sipho_Gp157 PF05565.6 OAJ16257.1 - 5 6.6 16.8 2 7.9 4.7 2.3 1 1 1 2 2 2 0 Siphovirus Gp157 CorA PF01544.13 OAJ16257.1 - 5.4 5.9 6.3 7.6 5.4 4.1 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein KxDL PF10241.4 OAJ16257.1 - 5.6 6.9 7.7 1.2 9.1 1.3 2.6 1 1 2 3 3 3 0 Uncharacterized conserved protein Cep57_CLD PF14073.1 OAJ16257.1 - 5.6 6.7 24.2 0.97 9.2 8.6 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 ATG16 PF08614.6 OAJ16257.1 - 5.9 6.6 24.8 0.35 10.6 5.6 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Prefoldin PF02996.12 OAJ16257.1 - 6.8 6.3 22.8 44 3.7 0.4 3.9 1 1 0 2 2 2 0 Prefoldin subunit DUF724 PF05266.9 OAJ16257.1 - 7.1 6.2 24.4 5.8 6.4 6.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Syntaxin-6_N PF09177.6 OAJ16257.1 - 8.5 6.8 18.9 1 9.8 5.8 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FemAB PF02388.11 OAJ16257.1 - 8.7 4.8 15.8 1.3 7.6 2.3 2.1 1 1 0 2 2 2 0 FemAB family OmpH PF03938.9 OAJ16257.1 - 9.4 6.1 22.4 5.9e+02 0.3 15.4 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Tup_N PF08581.5 OAJ16257.1 - 9.6 6.4 14.7 0.68 10.1 1.8 2.7 2 1 0 2 2 2 0 Tup N-terminal Aminotran_5 PF00266.14 OAJ16258.1 - 1.7e-29 102.7 0.0 2.4e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 OAJ16258.1 - 0.00041 20.1 0.0 0.0014 18.5 0.0 1.9 2 1 0 2 2 2 1 B12 binding domain Beta_elim_lyase PF01212.16 OAJ16258.1 - 0.01 15.0 0.0 0.07 12.2 0.0 1.9 1 1 0 1 1 1 0 Beta-eliminating lyase UPF0180 PF03698.8 OAJ16258.1 - 0.1 12.4 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) DUF4098 PF13345.1 OAJ16259.1 - 8e-10 38.5 6.9 4.5e-07 29.7 0.0 4.9 4 2 2 6 6 6 4 Domain of unknown function (DUF4098) TPR_11 PF13414.1 OAJ16285.1 - 3.6e-37 125.8 48.9 5.3e-10 38.8 1.9 13.3 10 5 3 13 13 13 10 TPR repeat TPR_1 PF00515.23 OAJ16285.1 - 1.6e-29 100.2 29.1 3.6e-05 23.1 0.2 13.9 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ16285.1 - 2.1e-25 86.5 8.8 0.0061 16.2 0.0 12.9 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ16285.1 - 9.3e-25 84.5 71.5 0.00011 21.8 1.0 19.1 20 0 0 20 20 19 6 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ16285.1 - 1.6e-23 81.0 93.1 2.1e-05 24.7 0.2 20.0 14 4 6 20 20 20 7 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ16285.1 - 7.3e-21 74.2 126.9 5.7e-06 26.8 1.4 19.4 14 6 6 21 21 20 7 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ16285.1 - 4.4e-20 70.1 27.7 0.0025 17.8 0.1 14.8 18 0 0 18 18 17 4 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ16285.1 - 1.3e-19 69.8 60.5 6.2e-09 35.6 1.3 14.0 10 6 4 14 14 14 5 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ16285.1 - 4.9e-11 42.8 69.5 0.00058 20.1 0.3 12.5 11 4 2 13 13 12 5 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ16285.1 - 8.4e-10 38.4 34.1 0.02 15.3 0.0 13.6 14 0 0 14 14 13 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ16285.1 - 4.9e-09 35.3 31.9 0.13 12.1 0.0 11.5 10 0 0 10 10 10 4 Tetratricopeptide repeat Apc3 PF12895.2 OAJ16285.1 - 2.9e-06 27.3 23.0 0.0017 18.4 0.4 8.4 9 0 0 9 9 9 2 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 OAJ16285.1 - 0.021 14.2 3.4 4.5 6.6 0.1 4.4 3 2 1 4 4 4 0 26S proteasome subunit RPN7 ChAPs PF09295.5 OAJ16285.1 - 0.22 10.2 3.1 6.8 5.3 0.0 3.0 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.1 OAJ16285.1 - 0.3 10.9 50.6 1.1 9.1 0.8 11.7 10 2 2 12 12 11 0 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ16285.1 - 1.6 8.9 41.4 0.87 9.7 0.7 8.5 6 3 0 8 8 7 0 Tetratricopeptide repeat Exo_endo_phos PF03372.18 OAJ16286.1 - 4.9e-16 59.4 0.0 6.3e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 OAJ16287.1 - 3.2e-45 153.4 0.0 1.2e-44 151.5 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 OAJ16287.1 - 5.2e-12 45.6 16.0 3.8e-08 33.2 4.9 3.4 3 1 0 3 3 3 2 LIM domain C1_1 PF00130.17 OAJ16287.1 - 2e-05 24.2 7.2 2e-05 24.2 5.0 3.4 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Serglycin PF04360.7 OAJ16287.1 - 0.018 14.7 0.2 0.018 14.7 0.2 6.3 6 1 0 6 6 6 0 Serglycin DUF2559 PF10832.3 OAJ16287.1 - 0.028 14.1 0.1 0.085 12.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) PGA2 PF07543.7 OAJ16287.1 - 0.057 13.2 6.3 0.25 11.1 4.3 2.1 1 0 0 1 1 1 0 Protein trafficking PGA2 Nup88 PF10168.4 OAJ16287.1 - 0.25 9.1 6.8 0.46 8.2 4.7 1.3 1 0 0 1 1 1 0 Nuclear pore component KH_1 PF00013.24 OAJ16288.1 - 7.9e-29 99.0 1.0 1.6e-09 37.2 0.0 5.6 6 0 0 6 6 6 4 KH domain KH_3 PF13014.1 OAJ16288.1 - 1.1e-20 72.8 2.5 5.4e-07 29.1 0.1 5.0 4 0 0 4 4 4 4 KH domain UQ_con PF00179.21 OAJ16289.1 - 1.9e-12 46.8 0.0 2.5e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF202 PF02656.10 OAJ16290.1 - 1.1e-12 48.0 5.4 1.1e-12 48.0 3.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) LHC PF00556.15 OAJ16290.1 - 0.078 12.8 0.2 0.078 12.8 0.2 2.3 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit DUF2615 PF11027.3 OAJ16290.1 - 0.34 10.8 0.1 0.34 10.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DUF2207 PF09972.4 OAJ16290.1 - 0.41 9.1 2.6 0.18 10.3 0.6 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DnaJ PF00226.26 OAJ16291.1 - 3.2e-21 74.8 0.4 6e-21 73.9 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain LMBR1 PF04791.11 OAJ16291.1 - 0.22 10.0 1.1 0.23 9.9 0.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF966 PF06136.8 OAJ16291.1 - 1.4 8.3 8.8 1.8 7.9 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) ENTH PF01417.15 OAJ16315.1 - 7.3e-48 161.5 0.0 1.6e-47 160.4 0.0 1.6 1 0 0 1 1 1 1 ENTH domain UIM PF02809.15 OAJ16315.1 - 0.0056 16.1 9.0 0.054 13.0 0.7 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif ANTH PF07651.11 OAJ16315.1 - 0.19 10.3 10.7 0.0047 15.6 1.5 2.4 2 1 0 2 2 2 0 ANTH domain DUF4192 PF13830.1 OAJ16315.1 - 3.9 7.0 8.7 6.8 6.2 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Porin_3 PF01459.17 OAJ16316.1 - 9.6e-59 198.9 0.1 1.1e-58 198.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin PHD PF00628.24 OAJ16318.1 - 0.0024 17.5 7.9 0.0024 17.5 5.5 2.6 2 0 0 2 2 2 1 PHD-finger rve PF00665.21 OAJ16319.1 - 1.5e-06 28.3 0.1 2.6e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.1 OAJ16319.1 - 0.05 13.2 0.1 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Fusion_gly_K PF01621.12 OAJ16319.1 - 0.2 10.6 0.4 0.72 8.8 0.0 1.8 2 0 0 2 2 2 0 Cell fusion glycoprotein K Cyanate_lyase PF02560.9 OAJ16320.1 - 4.3e-35 119.0 0.0 6.3e-35 118.5 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 OAJ16320.1 - 0.00044 20.4 0.0 0.00069 19.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 OAJ16320.1 - 0.0029 17.6 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 OAJ16320.1 - 0.014 15.1 0.0 0.036 13.9 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix KorB PF08535.5 OAJ16320.1 - 0.066 13.3 0.0 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 KorB domain HTH_38 PF13936.1 OAJ16320.1 - 0.091 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF221 PF02714.10 OAJ16321.1 - 5.4e-95 317.9 21.7 8.9e-95 317.2 15.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAJ16321.1 - 6.8e-37 126.4 1.8 2.1e-36 124.8 1.3 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 OAJ16321.1 - 1.8e-20 73.2 3.8 2.9e-20 72.5 2.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 OAJ16321.1 - 2e-13 50.0 0.0 5.8e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein LSM PF01423.17 OAJ16322.1 - 1.3e-17 63.1 0.1 1.5e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 OAJ16322.1 - 1.3e-06 28.2 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Velvet PF11754.3 OAJ16323.1 - 4.6e-43 147.1 8.5 5.6e-31 107.7 0.0 3.3 3 0 0 3 3 3 2 Velvet factor DnaJ PF00226.26 OAJ16324.1 - 1.1e-21 76.2 1.8 1.6e-21 75.7 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain DUF1843 PF08898.5 OAJ16324.1 - 0.044 13.8 1.7 0.54 10.3 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) RPT PF13446.1 OAJ16324.1 - 0.063 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein Aminotran_3 PF00202.16 OAJ16348.1 - 2.7e-82 276.3 0.0 3.8e-82 275.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III DUF1311 PF07007.7 OAJ16348.1 - 0.018 15.1 0.6 0.06 13.4 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) MS_channel PF00924.13 OAJ16349.1 - 2.6e-16 59.5 0.6 4.3e-16 58.8 0.4 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.1 OAJ16349.1 - 0.016 15.3 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 OAJ16349.1 - 0.038 13.3 0.0 0.098 12.0 0.0 1.7 1 0 0 1 1 1 0 EF hand Fringe PF02434.11 OAJ16350.1 - 5.9e-06 25.6 0.2 1.4e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 OAJ16350.1 - 0.066 12.7 0.0 1.3 8.5 0.0 2.2 1 1 0 1 1 1 0 Galactosyltransferase MS_channel PF00924.13 OAJ16351.1 - 5.6e-24 84.6 0.8 1e-23 83.7 0.5 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.1 OAJ16351.1 - 0.024 14.7 0.1 0.067 13.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 OAJ16351.1 - 0.036 13.3 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 EF hand Flu_PB2 PF00604.12 OAJ16351.1 - 0.21 9.4 0.0 0.32 8.7 0.0 1.2 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB2 DUF4328 PF14219.1 OAJ16351.1 - 0.85 8.8 12.5 0.28 10.4 5.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4328) Flavin_Reduct PF01613.13 OAJ16352.1 - 1.2e-24 86.8 0.0 1.7e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain BCS1_N PF08740.6 OAJ16354.1 - 1.6e-49 168.0 0.0 2.9e-49 167.2 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 OAJ16354.1 - 5.8e-17 62.1 0.0 1.8e-16 60.5 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 OAJ16354.1 - 0.00014 22.6 0.0 0.00034 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 OAJ16354.1 - 0.00029 19.8 0.0 0.00063 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 OAJ16354.1 - 0.002 17.6 0.2 0.0092 15.4 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ16354.1 - 0.0022 17.9 1.3 0.015 15.2 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.1 OAJ16354.1 - 0.0035 17.3 0.0 0.0055 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAJ16354.1 - 0.004 16.5 0.0 0.021 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAJ16354.1 - 0.017 15.2 0.0 0.047 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 OAJ16354.1 - 0.032 13.9 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 OAJ16354.1 - 0.038 14.2 0.1 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 OAJ16354.1 - 0.056 13.3 0.2 0.21 11.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAJ16354.1 - 0.083 12.6 0.6 0.58 9.9 0.0 2.8 3 0 0 3 3 2 0 Part of AAA domain AAA_24 PF13479.1 OAJ16354.1 - 0.098 12.2 0.1 0.3 10.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 OAJ16354.1 - 0.1 11.6 0.0 0.37 9.8 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.18 OAJ16354.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2106 PF09879.4 OAJ16356.1 - 0.048 12.9 0.2 0.085 12.1 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) ABC_tran PF00005.22 OAJ16382.1 - 2.4e-33 115.3 0.0 5.5e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 OAJ16382.1 - 3.6e-29 102.0 7.3 4.6e-29 101.6 5.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 OAJ16382.1 - 9.2e-08 32.3 0.0 3.1e-05 24.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 OAJ16382.1 - 0.0024 17.3 0.1 0.0063 16.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ16382.1 - 0.0061 16.5 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 OAJ16382.1 - 0.013 15.7 0.0 0.12 12.5 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 OAJ16382.1 - 0.018 14.2 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAJ16382.1 - 0.031 15.0 0.0 0.069 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 OAJ16382.1 - 0.034 14.2 0.0 0.17 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 OAJ16382.1 - 0.14 12.4 1.0 0.19 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain Spore_coat_CotO PF14153.1 OAJ16384.1 - 7.5 5.9 7.2 12 5.3 5.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Tom37_C PF11801.3 OAJ16384.1 - 8.6 6.1 5.6 14 5.4 3.9 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF2457 PF10446.4 OAJ16385.1 - 0.002 16.9 1.5 0.0024 16.6 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) ERM PF00769.14 OAJ16385.1 - 0.027 13.9 13.4 0.033 13.7 9.3 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Urease_gamma PF00547.13 OAJ16385.1 - 0.043 13.8 1.1 0.068 13.2 0.8 1.3 1 0 0 1 1 1 0 Urease, gamma subunit Spore_coat_CotO PF14153.1 OAJ16385.1 - 0.1 12.0 7.1 0.14 11.6 4.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Tom37_C PF11801.3 OAJ16385.1 - 0.15 11.9 5.5 0.19 11.5 3.8 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain Nucleo_P87 PF07267.6 OAJ16385.1 - 0.3 9.7 4.4 0.35 9.4 3.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 eIF3_subunit PF08597.5 OAJ16385.1 - 0.36 10.3 13.2 0.46 9.9 9.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4192 PF13830.1 OAJ16385.1 - 0.81 9.2 13.6 1 8.9 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) HemY_N PF07219.8 OAJ16385.1 - 1.7 8.2 7.4 3.2 7.3 5.1 1.4 1 0 0 1 1 1 0 HemY protein N-terminus Ycf1 PF05758.7 OAJ16385.1 - 5.8 4.4 5.4 6.4 4.3 3.7 1.0 1 0 0 1 1 1 0 Ycf1 Fungal_trans PF04082.13 OAJ16386.1 - 8.2e-21 74.0 0.0 2.1e-20 72.6 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ16386.1 - 3.3e-09 36.5 10.9 5.4e-09 35.8 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spindle_Spc25 PF08234.7 OAJ16387.1 - 8e-14 51.4 0.0 2.1e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 ERM PF00769.14 OAJ16387.1 - 0.03 13.8 13.9 0.057 12.9 9.7 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Macoilin PF09726.4 OAJ16387.1 - 0.04 12.2 3.8 0.048 11.9 2.6 1.1 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 OAJ16387.1 - 0.049 13.2 9.3 0.087 12.4 6.5 1.4 1 0 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 OAJ16387.1 - 0.11 12.3 11.6 0.2 11.5 8.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 OAJ16387.1 - 0.19 11.4 16.5 0.37 10.5 11.5 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 OAJ16387.1 - 0.82 8.5 7.2 1.4 7.7 5.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Creb_binding PF09030.5 OAJ16387.1 - 7.1 6.8 11.0 0.2 11.8 1.7 2.6 3 1 0 3 3 3 0 Creb binding CAF-1_p150 PF11600.3 OAJ16387.1 - 9.5 5.5 13.0 23 4.2 9.0 1.6 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal APG6 PF04111.7 OAJ16387.1 - 9.6 5.1 12.5 15 4.5 8.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Pkinase PF00069.20 OAJ16388.1 - 6.4e-56 189.3 0.0 4.1e-55 186.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ16388.1 - 1.5e-27 96.2 0.0 1.2e-18 67.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ16388.1 - 0.00011 21.2 0.2 0.02 13.8 0.0 2.5 3 0 0 3 3 3 2 Kinase-like Myc-LZ PF02344.10 OAJ16388.1 - 0.003 17.1 2.1 2.1 8.0 0.0 2.5 2 0 0 2 2 2 2 Myc leucine zipper domain APH PF01636.18 OAJ16388.1 - 0.011 15.4 0.5 0.17 11.5 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 OAJ16388.1 - 0.052 12.6 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 OAJ16388.1 - 0.074 13.5 1.5 0.15 12.6 0.0 2.4 2 0 0 2 2 2 0 Protein kinase C terminal domain RIO1 PF01163.17 OAJ16388.1 - 0.075 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family GST_C_2 PF13410.1 OAJ16408.1 - 1.1e-16 60.4 0.0 2e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAJ16408.1 - 7.4e-16 57.9 0.0 1.5e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ16408.1 - 3.5e-07 30.1 0.0 6.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ16408.1 - 1.3e-06 28.7 0.0 2.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAJ16408.1 - 0.0019 18.3 0.0 2 8.7 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Pmp3 PF01679.12 OAJ16410.1 - 2.6e-12 46.2 3.2 3.7e-12 45.7 2.2 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PMM PF03332.8 OAJ16411.1 - 2.9e-101 337.6 0.4 3.5e-101 337.3 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 OAJ16411.1 - 4.6e-05 23.1 0.0 0.00026 20.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF600 PF04634.7 OAJ16411.1 - 0.072 13.1 0.1 0.19 11.7 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF600 Response_reg PF00072.19 OAJ16412.1 - 7.1e-20 71.0 0.0 2.1e-19 69.6 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 OAJ16412.1 - 2.6e-17 62.5 0.2 5.4e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 OAJ16412.1 - 7e-08 32.3 0.2 5.1e-07 29.5 0.1 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Sec63 PF02889.11 OAJ16413.1 - 3.9e-44 151.1 0.0 5.7e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.26 OAJ16413.1 - 6e-10 38.8 0.0 1.2e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ16413.1 - 7.3e-09 35.3 0.0 1.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_5 PF14520.1 OAJ16413.1 - 0.014 15.5 0.1 0.058 13.5 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain UvrD-helicase PF00580.16 OAJ16413.1 - 0.023 14.0 0.6 0.079 12.2 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain T2SE PF00437.15 OAJ16413.1 - 0.029 13.2 0.0 0.052 12.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-CCHC PF00098.18 OAJ16438.1 - 7.8e-10 38.2 37.9 5.6e-07 29.1 1.1 5.7 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ16438.1 - 0.055 12.9 15.4 2.5 7.6 0.2 3.4 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ16438.1 - 7.7 6.2 29.0 0.75 9.5 0.6 4.7 5 0 0 5 5 5 0 Zinc knuckle 2-Hacid_dh_C PF02826.14 OAJ16439.1 - 2.3e-40 137.6 0.0 2.8e-37 127.5 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAJ16439.1 - 2.7e-24 85.1 0.0 3.6e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AAA PF00004.24 OAJ16441.1 - 3.8e-14 53.0 0.0 8.2e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 OAJ16441.1 - 1.3e-12 47.7 0.0 6.8e-12 45.3 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 OAJ16441.1 - 5.4e-08 33.0 0.0 1.7e-07 31.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain Rep_fac_C PF08542.6 OAJ16441.1 - 3.5e-06 26.9 0.0 8.1e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_19 PF13245.1 OAJ16441.1 - 9e-06 25.3 0.0 6.4e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Rad17 PF03215.10 OAJ16441.1 - 9.3e-06 24.5 0.0 0.00088 18.0 0.0 2.2 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 OAJ16441.1 - 0.00027 20.9 0.9 0.015 15.2 0.0 3.2 2 1 0 3 3 3 1 AAA ATPase domain DUF2075 PF09848.4 OAJ16441.1 - 0.00033 19.7 0.0 0.00051 19.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 OAJ16441.1 - 0.00059 19.8 0.1 0.019 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 OAJ16441.1 - 0.00074 18.6 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 OAJ16441.1 - 0.0018 17.8 0.0 0.0068 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 OAJ16441.1 - 0.0019 17.6 0.0 0.0052 16.2 0.0 1.7 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.1 OAJ16441.1 - 0.0032 17.0 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 OAJ16441.1 - 0.013 14.7 0.0 0.081 12.0 0.0 2.1 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 OAJ16441.1 - 0.023 14.2 0.2 0.051 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAJ16441.1 - 0.028 13.8 0.2 0.13 11.6 0.2 2.3 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 OAJ16441.1 - 0.046 13.1 0.1 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.8 OAJ16441.1 - 0.086 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 OAJ16441.1 - 0.088 12.2 0.1 0.78 9.1 0.0 2.1 1 1 1 2 2 2 0 AAA-like domain AAA_5 PF07728.9 OAJ16441.1 - 0.09 12.4 0.3 0.94 9.1 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 OAJ16441.1 - 0.14 10.7 0.0 0.27 9.7 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain p450 PF00067.17 OAJ16442.1 - 2.5e-49 168.0 0.0 3.3e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3071 PF11268.3 OAJ16442.1 - 0.08 12.6 0.1 0.18 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3071) p450 PF00067.17 OAJ16443.1 - 1.6e-53 181.9 0.0 2e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4142 PF13628.1 OAJ16443.1 - 0.035 14.1 0.1 0.065 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) Mito_carr PF00153.22 OAJ16444.1 - 4.1e-50 167.4 5.3 1.2e-16 60.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SRP1_TIP1 PF00660.12 OAJ16444.1 - 0.093 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Seripauperin and TIP1 family Smg4_UPF3 PF03467.10 OAJ16445.1 - 2e-32 112.6 0.0 2e-32 112.6 0.0 2.5 2 1 0 2 2 2 1 Smg-4/UPF3 family zf-CCCH PF00642.19 OAJ16473.1 - 2.1e-22 78.2 33.0 1.1e-06 28.1 0.2 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 OAJ16473.1 - 3.4e-06 26.7 1.5 3.4e-06 26.7 1.1 2.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ16473.1 - 0.0088 15.7 3.8 0.024 14.3 0.3 2.5 2 0 0 2 2 2 1 Zinc knuckle NPL4 PF05021.10 OAJ16474.1 - 1.1e-84 284.2 0.0 1.7e-82 277.0 0.0 3.2 2 1 0 2 2 2 1 NPL4 family zf-NPL4 PF05020.10 OAJ16474.1 - 2.9e-65 218.4 0.1 4.6e-65 217.7 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 OAJ16474.1 - 0.00016 21.9 0.0 0.00035 20.7 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 UIM PF02809.15 OAJ16474.1 - 0.0069 15.8 0.6 0.02 14.4 0.4 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif zf-RanBP PF00641.13 OAJ16474.1 - 8.6 5.5 7.8 0.15 11.1 0.5 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Imm34 PF15596.1 OAJ16475.1 - 0.0074 16.4 1.7 4.5 7.4 0.1 2.9 2 1 0 2 2 2 2 Immunity protein 34 T2SF PF00482.18 OAJ16475.1 - 0.011 15.6 1.2 5 7.0 0.1 2.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F HoxA13_N PF12284.3 OAJ16478.1 - 0.19 11.8 2.5 0.62 10.2 1.5 1.9 1 1 1 2 2 2 0 Hox protein A13 N terminal zf-CCCH PF00642.19 OAJ16498.1 - 0.18 11.5 10.3 1.6 8.5 2.1 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MFS_1 PF07690.11 OAJ16499.1 - 1.5e-33 115.9 36.8 1.1e-27 96.7 0.2 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily DDE_1 PF03184.14 OAJ16501.1 - 7.4e-31 106.9 0.0 9.6e-31 106.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 OAJ16501.1 - 6.8e-08 32.3 0.0 5.8e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease SRP-alpha_N PF04086.8 OAJ16503.1 - 0.11 11.9 18.2 0.14 11.5 12.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CobN-Mg_chel PF02514.11 OAJ16503.1 - 2 5.6 13.9 2.5 5.3 9.6 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase MCM_N PF14551.1 OAJ16503.1 - 2.4 8.6 4.4 3.5 8.1 3.1 1.5 1 1 0 1 1 1 0 MCM N-terminal domain GAGA_bind PF06217.7 OAJ16503.1 - 9 6.1 13.8 14 5.5 9.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family zf-C2H2_2 PF12756.2 OAJ16504.1 - 0.0064 16.5 0.0 0.0076 16.3 0.0 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 OAJ16504.1 - 0.062 12.9 0.1 0.098 12.3 0.1 1.3 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_jaz PF12171.3 OAJ16504.1 - 2.1 8.5 5.6 0.36 11.0 0.7 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 OAJ16505.1 - 0.054 13.6 0.1 0.098 12.7 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) GPI-anchored PF10342.4 OAJ16531.1 - 1.2e-11 44.9 0.1 2.6e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NTF2 PF02136.15 OAJ16531.1 - 0.093 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain GnsAB PF08178.6 OAJ16531.1 - 0.17 11.5 0.1 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 GnsA/GnsB family Dak1 PF02733.12 OAJ16532.1 - 6.3e-87 291.1 0.6 1.4e-86 290.0 0.4 1.5 1 1 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 OAJ16532.1 - 4.3e-37 127.4 5.0 1e-36 126.2 3.5 1.6 1 0 0 1 1 1 1 DAK2 domain DOT1 PF08123.8 OAJ16532.1 - 0.17 11.1 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Peptidase_S28 PF05577.7 OAJ16533.1 - 2.4e-38 131.8 0.5 2e-33 115.6 0.0 2.9 3 0 0 3 3 3 2 Serine carboxypeptidase S28 HEV_ORF1 PF02444.11 OAJ16533.1 - 0.13 12.4 0.9 0.67 10.1 0.0 2.3 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) CGI-121 PF08617.5 OAJ16534.1 - 8.2e-27 93.8 0.0 1.2e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Kinase binding protein CGI-121 SKN1 PF03935.10 OAJ16535.1 - 3.5e-175 582.9 0.0 4.5e-175 582.5 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 OAJ16535.1 - 0.0015 17.8 0.0 0.027 13.7 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Iso_dh PF00180.15 OAJ16536.1 - 1.3e-117 392.6 0.0 1.5e-117 392.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase YebG PF07130.7 OAJ16536.1 - 0.1 12.2 0.1 14 5.4 0.0 2.5 2 0 0 2 2 2 0 YebG protein RCC1_2 PF13540.1 OAJ16537.1 - 0.00023 20.6 13.2 0.12 12.0 0.8 4.9 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 OAJ16537.1 - 0.0015 18.7 6.3 21 5.4 0.0 6.0 6 0 0 6 6 6 1 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 OAJ16537.1 - 0.01 15.5 0.2 0.028 14.1 0.1 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 OAJ16537.1 - 0.053 13.1 0.1 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 F-box domain DUF2034 PF10356.4 OAJ16538.1 - 8.7e-18 64.1 5.8 1.5e-17 63.3 0.0 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 OAJ16538.1 - 4.3e-06 26.5 0.0 1.2e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Restriction endonuclease MSA_2 PF00985.12 OAJ16538.1 - 0.013 15.6 1.9 0.013 15.6 1.3 1.8 2 0 0 2 2 2 0 Merozoite Surface Antigen 2 (MSA-2) family Diphtheria_T PF02764.9 OAJ16538.1 - 0.32 10.7 1.5 0.55 9.9 1.0 1.3 1 0 0 1 1 1 0 Diphtheria toxin, T domain AT_hook PF02178.14 OAJ16538.1 - 1.2 9.0 18.2 0.27 11.0 1.1 4.1 3 0 0 3 3 3 0 AT hook motif Euplotes_phero PF05842.6 OAJ16538.1 - 2.1 8.7 7.6 4 7.8 5.3 1.4 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein SRP-alpha_N PF04086.8 OAJ16539.1 - 4.3e-47 160.8 0.0 6.6e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 OAJ16539.1 - 1.2e-45 155.4 0.0 1.3e-28 99.7 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain CbiA PF01656.18 OAJ16539.1 - 1.7e-07 30.8 0.0 3.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 OAJ16539.1 - 2.3e-06 27.6 0.0 8.2e-06 25.8 0.0 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.1 OAJ16539.1 - 0.0032 17.4 1.8 0.047 13.6 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 OAJ16539.1 - 0.004 17.2 0.1 0.02 15.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 OAJ16539.1 - 0.012 15.2 0.0 0.035 13.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 OAJ16539.1 - 0.021 13.6 0.0 0.17 10.6 0.0 2.3 3 0 0 3 3 3 0 ArgK protein Fer4_NifH PF00142.13 OAJ16539.1 - 0.098 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.10 OAJ16539.1 - 0.16 10.9 0.0 3.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Anion-transporting ATPase NTPase_1 PF03266.10 OAJ16539.1 - 0.16 11.6 0.0 1 9.0 0.0 2.1 1 1 0 1 1 1 0 NTPase Sigma70_ner PF04546.8 OAJ16539.1 - 3.9 7.0 5.7 7.3 6.1 3.9 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Mto2_bdg PF12808.2 OAJ16560.1 - 0.012 15.6 0.1 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region ADIP PF11559.3 OAJ16560.1 - 0.032 14.1 0.8 0.042 13.7 0.5 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 OAJ16560.1 - 0.057 13.2 0.1 0.068 12.9 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Cornifin PF02389.10 OAJ16561.1 - 0.0032 17.2 2.9 0.0076 16.0 2.0 1.5 1 1 0 1 1 1 1 Cornifin (SPRR) family BRAP2 PF07576.7 OAJ16562.1 - 4.3e-20 71.3 0.0 1e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 OAJ16562.1 - 8.7e-17 60.9 4.5 8.7e-17 60.9 3.1 1.8 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 OAJ16562.1 - 1.1e-08 34.6 10.6 1.1e-08 34.6 7.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 OAJ16562.1 - 7.8e-06 25.9 4.5 7.8e-06 25.9 3.1 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 OAJ16562.1 - 2.9e-05 23.6 9.4 2.9e-05 23.6 6.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ16562.1 - 6.2e-05 22.6 8.3 6.2e-05 22.6 5.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain CENP-Q PF13094.1 OAJ16562.1 - 0.00059 19.9 7.3 0.6 10.1 0.0 2.6 2 0 0 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit zf-RING_UBOX PF13445.1 OAJ16562.1 - 0.00065 19.3 5.4 0.0049 16.5 1.7 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 OAJ16562.1 - 0.00065 19.6 10.1 0.00065 19.6 7.0 2.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ16562.1 - 0.00098 18.7 8.0 0.00098 18.7 5.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAJ16562.1 - 0.0012 18.6 4.0 0.0012 18.6 2.8 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_6 PF14259.1 OAJ16562.1 - 0.0016 18.3 0.0 0.0045 16.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DEC-1_C PF04626.8 OAJ16562.1 - 0.014 15.5 5.4 0.032 14.3 3.7 1.5 1 0 0 1 1 1 0 Dec-1 protein, C terminal region zf-RING_4 PF14570.1 OAJ16562.1 - 0.054 13.0 6.9 0.12 12.0 4.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 OAJ16562.1 - 0.086 12.4 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_RING PF05883.6 OAJ16562.1 - 0.21 11.3 0.6 0.47 10.2 0.4 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Spc24 PF08286.6 OAJ16562.1 - 2.1 8.0 5.3 0.63 9.7 0.1 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 zf-RING_6 PF14835.1 OAJ16562.1 - 5.3 6.8 11.8 0.04 13.6 1.9 2.1 2 0 0 2 2 1 0 zf-RING of BARD1-type protein VTC PF09359.5 OAJ16563.1 - 1e-98 329.8 0.0 2e-98 328.8 0.0 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 OAJ16563.1 - 2.3e-30 106.3 15.4 1.3e-29 103.9 5.9 3.2 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 OAJ16563.1 - 4.3e-12 46.0 1.6 6.5e-12 45.4 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3649 PF12365.3 OAJ16565.1 - 0.24 10.9 3.1 0.27 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) Lys PF00062.15 OAJ16566.1 - 0.13 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family RRM_6 PF14259.1 OAJ16587.1 - 0.0002 21.2 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ16587.1 - 0.0023 17.5 0.0 0.0061 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ebola_NP PF05505.7 OAJ16587.1 - 0.28 9.1 11.6 0.59 8.1 8.1 1.6 1 0 0 1 1 1 0 Ebola nucleoprotein TPR_12 PF13424.1 OAJ16588.1 - 9.2e-05 22.3 12.5 0.0091 15.9 0.1 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ16588.1 - 0.071 12.7 6.6 1.3 8.7 0.0 3.8 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 OAJ16588.1 - 0.31 11.0 0.0 0.31 11.0 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Sec63 PF02889.11 OAJ16589.1 - 3.1e-78 263.1 0.0 4.8e-78 262.5 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 OAJ16589.1 - 4e-40 137.0 2.5 1.1e-28 99.8 0.0 4.0 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.10 OAJ16589.1 - 3.1e-10 40.1 0.0 3.7e-08 33.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 OAJ16589.1 - 2.8e-06 27.1 0.0 0.0003 20.5 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 OAJ16589.1 - 0.00042 20.4 0.3 0.0069 16.5 0.0 3.1 4 0 0 4 4 4 1 AAA domain T2SE PF00437.15 OAJ16589.1 - 0.0083 15.0 0.2 0.67 8.8 0.0 2.7 3 0 0 3 3 3 1 Type II/IV secretion system protein UvrD-helicase PF00580.16 OAJ16589.1 - 0.094 12.0 0.2 9.7 5.3 0.0 2.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Prim_Zn_Ribbon PF08273.7 OAJ16590.1 - 0.068 13.2 0.2 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase RRN7 PF11781.3 OAJ16590.1 - 0.11 11.9 0.2 0.27 10.7 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF3759 PF12585.3 OAJ16591.1 - 1.9e-41 139.8 10.1 2.1e-41 139.7 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) GTP_EFTU PF00009.22 OAJ16592.1 - 1.9e-51 174.1 0.0 3.3e-51 173.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 OAJ16592.1 - 7.4e-13 48.1 0.0 1.6e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 OAJ16592.1 - 6.1e-09 35.5 0.0 1.4e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 OAJ16592.1 - 9.9e-05 22.3 0.2 0.001 19.1 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 OAJ16592.1 - 0.0015 18.1 0.0 0.0086 15.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 OAJ16592.1 - 0.0084 16.0 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Peptidase_M43 PF05572.8 OAJ16593.1 - 3.2e-19 69.0 0.7 3.2e-19 69.0 0.5 1.7 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 OAJ16593.1 - 8e-07 29.6 2.6 2e-06 28.3 0.3 2.4 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 OAJ16593.1 - 1.3e-05 24.7 3.6 2.2e-05 24.0 2.5 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 OAJ16593.1 - 3.8e-05 23.8 7.1 7.9e-05 22.7 4.9 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAJ16593.1 - 4.5e-05 23.4 5.9 6.6e-05 22.9 4.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M7 PF02031.11 OAJ16593.1 - 0.0051 16.5 0.6 0.014 15.0 0.3 1.9 1 1 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M10 PF00413.19 OAJ16593.1 - 0.0062 16.2 0.2 0.0079 15.9 0.1 1.4 1 1 0 1 1 1 1 Matrixin Rax2 PF12768.2 OAJ16617.1 - 5.3e-82 275.2 1.2 3e-60 203.8 0.0 5.2 4 2 1 5 5 5 4 Cortical protein marker for cell polarity SH3_1 PF00018.23 OAJ16617.1 - 1e-14 53.6 0.0 1.9e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ16617.1 - 5.9e-12 44.9 0.0 1.4e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ16617.1 - 1.8e-07 30.5 0.0 3.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Kelch_2 PF07646.10 OAJ16617.1 - 0.11 12.2 6.1 8.8 6.2 0.0 4.8 5 0 0 5 5 5 0 Kelch motif DFP PF04127.10 OAJ16618.1 - 3.3e-20 72.4 0.0 1.1e-12 47.9 0.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Amidase PF01425.16 OAJ16619.1 - 5.5e-59 200.1 0.2 1.9e-58 198.3 0.1 1.8 1 1 0 1 1 1 1 Amidase FtsJ PF01728.14 OAJ16620.1 - 2.5e-43 148.1 0.0 3.2e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase HSP9_HSP12 PF04119.7 OAJ16621.1 - 8.8e-19 67.3 6.1 8.8e-19 67.3 4.2 1.7 2 0 0 2 2 2 1 Heat shock protein 9/12 DUF1744 PF08490.7 OAJ16622.1 - 8.4e-119 396.6 0.0 1.3e-118 396.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 OAJ16622.1 - 8.3e-63 212.2 0.0 1.7e-62 211.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 OAJ16622.1 - 4.4e-19 68.5 0.0 1.3e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 OAJ16622.1 - 2.5e-09 36.9 0.1 8.4e-09 35.2 0.0 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 OAJ16622.1 - 9.7e-06 25.4 0.0 4.8e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 RNase_H superfamily IDO PF01231.13 OAJ16623.1 - 2.3e-46 158.0 0.0 3.4e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase ubiquitin PF00240.18 OAJ16624.1 - 5.3e-09 35.3 0.1 9.9e-09 34.4 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 OAJ16624.1 - 5e-06 26.6 0.1 2.4e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 OAJ16624.1 - 0.00014 21.5 0.0 0.00016 21.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PI3K_rbd PF00794.13 OAJ16624.1 - 0.11 12.3 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain YukD PF08817.5 OAJ16624.1 - 0.13 12.8 0.0 0.15 12.6 0.0 1.3 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD 3Beta_HSD PF01073.14 OAJ16646.1 - 8.3e-20 70.6 0.0 3.2e-19 68.6 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAJ16646.1 - 3e-16 59.5 0.0 3.7e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ16646.1 - 1.9e-12 47.5 0.0 3.4e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAJ16646.1 - 5.2e-12 45.2 0.9 4.7e-11 42.1 0.6 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 OAJ16646.1 - 6.3e-08 32.1 0.1 9.2e-08 31.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 OAJ16646.1 - 5.1e-05 22.3 0.1 9.3e-05 21.4 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 OAJ16646.1 - 0.00096 19.1 0.4 0.0037 17.1 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_2 PF03446.10 OAJ16646.1 - 0.005 16.6 0.0 0.012 15.4 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 OAJ16646.1 - 0.016 14.5 0.1 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain KR PF08659.5 OAJ16646.1 - 0.017 14.7 0.8 0.33 10.6 0.6 2.2 1 1 0 1 1 1 0 KR domain RNase_PH PF01138.16 OAJ16647.1 - 1.5e-28 99.7 0.0 2.4e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 3HCDH_N PF02737.13 OAJ16648.1 - 6.9e-45 152.9 0.3 3.6e-44 150.5 0.2 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 OAJ16648.1 - 3.1e-35 120.4 0.0 6.6e-35 119.3 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF2680 PF10925.3 OAJ16648.1 - 0.052 13.4 0.2 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) F420_oxidored PF03807.12 OAJ16648.1 - 0.21 12.0 1.6 0.41 11.0 0.4 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_1 PF00667.15 OAJ16649.1 - 1.8e-51 174.7 0.0 2.6e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 OAJ16649.1 - 1.1e-06 29.2 0.0 6.6e-06 26.6 0.0 2.2 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.13 OAJ16649.1 - 0.00018 21.4 0.0 0.00053 19.9 0.0 1.8 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase FAD_binding_6 PF00970.19 OAJ16649.1 - 0.17 12.0 0.0 0.53 10.4 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain AP_endonuc_2 PF01261.19 OAJ16650.1 - 1.7e-11 43.8 0.0 0.00013 21.3 0.0 2.8 2 1 0 2 2 2 2 Xylose isomerase-like TIM barrel Proteasome PF00227.21 OAJ16651.1 - 2.6e-58 196.4 0.0 3.6e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAJ16651.1 - 8.3e-14 50.6 0.2 1.5e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature LSM PF01423.17 OAJ16652.1 - 2.5e-12 46.1 0.1 3.3e-12 45.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 OAJ16652.1 - 0.094 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Aminotran_1_2 PF00155.16 OAJ16653.1 - 5.6e-44 150.5 0.0 5.6e-43 147.2 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAJ16653.1 - 0.0025 17.0 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 OAJ16653.1 - 0.034 12.8 0.0 0.055 12.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V SAMP PF05924.6 OAJ16653.1 - 0.059 12.5 0.1 0.14 11.3 0.1 1.7 1 0 0 1 1 1 0 SAMP Motif Macoilin PF09726.4 OAJ16653.1 - 8.5 4.5 6.8 12 4.0 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_L16 PF00252.13 OAJ16654.1 - 3.2e-30 104.6 0.0 4e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L30_N PF08079.7 OAJ16655.1 - 1.1e-25 89.3 17.5 2.3e-25 88.4 12.1 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 OAJ16655.1 - 1.3e-17 63.0 0.8 3.1e-17 61.8 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Rep_Org_C PF06926.6 OAJ16655.1 - 0.1 12.7 0.5 0.19 11.8 0.4 1.4 1 0 0 1 1 1 0 Putative replisome organiser protein C-terminus DUF3419 PF11899.3 OAJ16656.1 - 8.6e-136 452.5 0.0 1.2e-135 452.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 OAJ16656.1 - 1.6e-10 40.9 0.0 2.4e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ16656.1 - 6.1e-08 32.3 0.0 1.2e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ16656.1 - 1.9e-07 30.4 0.0 4.1e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 OAJ16656.1 - 7e-07 29.6 0.0 0.00024 21.5 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ16656.1 - 7.2e-06 26.2 0.0 2.6e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ16656.1 - 1.6e-05 25.2 0.0 5e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ16656.1 - 2.1e-05 25.0 0.0 6.3e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ16656.1 - 0.00041 20.3 0.1 0.061 13.3 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Glutaredoxin PF00462.19 OAJ16682.1 - 2.1e-18 66.0 0.0 2.8e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 OAJ16682.1 - 0.00058 20.0 0.1 0.0021 18.2 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.9 OAJ16682.1 - 0.001 19.2 0.0 0.0012 19.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 OAJ16682.1 - 0.0018 18.0 0.1 0.0026 17.5 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin domain DUF953 PF06110.6 OAJ16682.1 - 0.0064 15.9 0.0 0.0071 15.7 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 OAJ16682.1 - 0.017 14.7 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin GST_N_3 PF13417.1 OAJ16682.1 - 0.028 14.6 0.0 0.038 14.2 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.1 OAJ16682.1 - 0.033 14.1 0.2 4.7 7.1 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin DSBA PF01323.15 OAJ16682.1 - 0.034 13.6 0.1 0.35 10.3 0.1 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_7 PF13899.1 OAJ16682.1 - 0.083 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like TusA PF01206.12 OAJ16682.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.4 1 1 0 1 1 1 0 Sulfurtransferase TusA Zn_ribbon_2 PF12674.2 OAJ16682.1 - 0.096 13.0 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative zinc ribbon domain DnaJ PF00226.26 OAJ16684.1 - 1.2e-06 28.1 0.1 1.7e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 OAJ16684.1 - 0.00014 21.6 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Pam16 DPBB_1 PF03330.13 OAJ16685.1 - 6.1e-06 26.1 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel FNIP_N PF14636.1 OAJ16685.1 - 1.1 9.7 9.1 1.8 9.0 6.3 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Mucin PF01456.12 OAJ16685.1 - 3.6 7.3 18.4 9.2 6.0 12.7 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Myb_DNA-binding PF00249.26 OAJ16687.1 - 5.5e-32 109.5 4.1 1.7e-10 40.7 0.0 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ16687.1 - 2.2e-31 107.7 0.2 7.8e-13 48.3 0.0 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 OAJ16687.1 - 0.0055 16.5 3.1 5.7 6.8 1.1 3.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 OAJ16687.1 - 9.9 6.3 6.9 41 4.4 0.1 3.3 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain WD40 PF00400.27 OAJ16688.1 - 2.9e-35 118.8 0.5 1.5e-08 34.1 0.0 7.5 6 1 1 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 OAJ16688.1 - 0.00033 18.9 0.2 0.0005 18.3 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 OAJ16688.1 - 0.00066 19.2 0.6 0.0015 18.0 0.4 1.7 1 1 0 1 1 1 1 PQQ-like domain Aminotran_1_2 PF00155.16 OAJ16689.1 - 1.5e-15 57.0 0.0 1.9e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 OAJ16689.1 - 6.8e-06 24.8 0.0 9.6e-06 24.3 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase HTH_Tnp_Tc5 PF03221.11 OAJ16690.1 - 6.5e-12 45.0 0.0 1.3e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Retrotrans_gag PF03732.12 OAJ16690.1 - 0.062 13.3 0.1 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein EXS PF03124.9 OAJ16691.1 - 4e-58 197.0 1.8 1.7e-52 178.6 1.9 2.2 2 0 0 2 2 2 2 EXS family MMgT PF10270.4 OAJ16718.1 - 2e-20 73.1 0.0 2.3e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter TctB PF07331.6 OAJ16718.1 - 0.055 13.1 0.0 0.062 12.9 0.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Sugar_tr PF00083.19 OAJ16720.1 - 3.4e-65 220.4 12.7 4e-65 220.1 8.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ16720.1 - 5.4e-13 48.3 20.0 5.4e-13 48.3 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ham1p_like PF01725.11 OAJ16721.1 - 7e-54 182.0 0.0 7.9e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family PIF1 PF05970.9 OAJ16722.1 - 1.5e-104 349.8 0.0 2.2e-104 349.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ16722.1 - 2.8e-62 209.7 0.1 1.4e-61 207.4 0.1 2.2 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Herpes_Helicase PF02689.9 OAJ16722.1 - 2.7e-08 32.1 0.1 7.8e-08 30.5 0.0 1.7 2 0 0 2 2 2 1 Helicase AAA_30 PF13604.1 OAJ16722.1 - 3.6e-07 29.9 0.1 6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ16722.1 - 0.00054 19.6 0.1 0.002 17.8 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 OAJ16722.1 - 0.0047 17.0 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain T2SE PF00437.15 OAJ16722.1 - 0.0094 14.8 0.0 0.028 13.3 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein PhoH PF02562.11 OAJ16722.1 - 0.2 10.8 0.0 14 4.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein CRISPR_Cse2 PF09485.5 OAJ16723.1 - 0.081 12.9 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Cation_efflux PF01545.16 OAJ16724.1 - 2.5e-74 249.8 5.9 1.3e-73 247.6 4.1 1.8 1 1 0 1 1 1 1 Cation efflux family DUF4632 PF15451.1 OAJ16726.1 - 0.01 15.7 0.1 0.01 15.7 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4632) NUP50 PF08911.6 OAJ16726.1 - 0.25 11.7 0.0 0.25 11.7 0.0 5.9 5 2 0 5 5 5 0 NUP50 (Nucleoporin 50 kDa) NOA36 PF06524.7 OAJ16726.1 - 2 7.6 16.2 3.5 6.7 11.2 1.3 1 0 0 1 1 1 0 NOA36 protein Abhydrolase_5 PF12695.2 OAJ16745.1 - 2.1e-09 37.3 0.8 5.5e-09 35.9 0.5 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ16745.1 - 1.3e-06 27.8 0.0 3.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 OAJ16745.1 - 0.00075 19.1 0.1 0.0072 15.9 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 OAJ16745.1 - 0.0044 15.9 0.1 0.2 10.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) GCR1_C PF12550.3 OAJ16746.1 - 0.00032 20.5 0.0 0.00054 19.7 0.0 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Metal_resist PF13801.1 OAJ16746.1 - 0.0049 16.8 0.1 0.025 14.5 0.0 2.0 2 0 0 2 2 2 1 Heavy-metal resistance SSP160 PF06933.6 OAJ16746.1 - 2 6.3 12.1 2.9 5.7 8.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dimer_Tnp_hAT PF05699.9 OAJ16747.1 - 8.7e-05 22.0 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FIVAR PF07554.8 OAJ16748.1 - 0.025 14.7 3.3 0.053 13.7 0.9 2.2 1 1 1 2 2 2 0 Uncharacterised Sugar-binding Domain Prominin PF05478.6 OAJ16748.1 - 0.066 10.7 0.2 0.083 10.4 0.1 1.0 1 0 0 1 1 1 0 Prominin FbpA PF05833.6 OAJ16748.1 - 0.075 11.5 0.2 0.088 11.3 0.1 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HCaRG PF07258.9 OAJ16748.1 - 0.13 11.8 0.8 2.2 7.7 0.4 2.0 1 1 1 2 2 2 0 HCaRG protein YwqJ-deaminase PF14431.1 OAJ16748.1 - 0.13 12.1 0.3 0.26 11.1 0.1 1.5 1 1 1 2 2 2 0 YwqJ-like deaminase BssS PF13991.1 OAJ16748.1 - 0.14 11.9 0.2 0.29 10.8 0.1 1.6 1 1 0 1 1 1 0 BssS protein family ATP-synt_DE PF00401.15 OAJ16748.1 - 2.2 8.2 8.6 0.45 10.4 0.6 2.4 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain HTH_Tnp_1_2 PF13022.1 OAJ16750.1 - 0.04 13.6 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase Lectin_leg-like PF03388.8 OAJ16779.1 - 8.7e-60 201.7 0.1 1.2e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family DUF3561 PF12084.3 OAJ16779.1 - 0.024 14.4 0.2 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) DUF1517 PF07466.6 OAJ16779.1 - 0.8 8.6 3.1 1.1 8.1 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Pribosyltran_N PF13793.1 OAJ16780.1 - 2.9e-44 149.5 0.3 9.8e-43 144.5 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 OAJ16780.1 - 3.2e-40 137.8 2.0 9.1e-33 113.5 0.1 2.8 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 OAJ16780.1 - 2.6e-11 43.3 0.6 1.8e-10 40.5 0.5 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 OAJ16780.1 - 0.078 12.1 0.1 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Nup160 PF11715.3 OAJ16781.1 - 2.4e-14 52.4 0.7 2e-10 39.4 0.0 3.1 2 1 0 2 2 2 2 Nucleoporin Nup120/160 FA_hydroxylase PF04116.8 OAJ16782.1 - 1.3e-10 41.6 10.5 1.3e-10 41.6 7.3 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF515 PF04415.7 OAJ16783.1 - 0.26 9.4 14.7 0.32 9.1 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Macoilin PF09726.4 OAJ16783.1 - 6.7 4.8 5.7 6.5 4.9 3.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Polysacc_deac_1 PF01522.16 OAJ16784.1 - 6.3e-23 80.7 0.0 1e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase nec1 PF10379.4 OAJ16784.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Virulence protein nec1 Polysacc_deac_1 PF01522.16 OAJ16785.1 - 2.5e-24 85.2 0.1 8.9e-24 83.4 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase Sporozoite_P67 PF05642.6 OAJ16785.1 - 0.14 10.0 11.5 0.2 9.5 7.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pex14_N PF04695.8 OAJ16785.1 - 0.42 10.6 6.8 1 9.4 1.7 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SSP160 PF06933.6 OAJ16785.1 - 6.2 4.6 23.6 9.4 4.0 16.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Peptidase_S10 PF00450.17 OAJ16786.1 - 1.1e-111 374.0 1.8 1.4e-111 373.6 1.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 OAJ16786.1 - 0.0011 18.9 0.0 0.0094 15.8 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Phasin PF05597.6 OAJ16786.1 - 0.038 13.7 0.9 0.068 12.9 0.6 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Apolipoprotein PF01442.13 OAJ16786.1 - 0.04 13.4 0.4 0.063 12.7 0.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TpcC PF12642.2 OAJ16786.1 - 0.12 11.9 0.1 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Conjugative transposon protein TcpC DEAD PF00270.24 OAJ16787.1 - 1e-13 51.1 0.0 2e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ16787.1 - 3e-07 30.2 0.0 5.4e-05 22.9 0.0 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Rib_5-P_isom_A PF06026.9 OAJ16817.1 - 1.6e-54 183.7 0.0 2.5e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 OAJ16817.1 - 0.037 13.6 0.1 0.81 9.3 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain Cellulase PF00150.13 OAJ16818.1 - 6.9e-12 45.1 0.1 1.5e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Presenilin PF01080.12 OAJ16819.1 - 0.2 10.4 1.5 0.25 10.1 1.0 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.7 OAJ16819.1 - 7 6.4 9.9 9.6 6.0 6.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Bin3 PF06859.7 OAJ16821.1 - 1.2e-14 54.2 0.0 2.1e-08 34.1 0.0 3.1 3 0 0 3 3 3 2 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 OAJ16821.1 - 1.6e-05 25.4 0.0 4.7e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ16821.1 - 0.0005 20.0 0.0 0.025 14.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ16821.1 - 0.00094 18.8 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ16821.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ16821.1 - 0.026 15.0 0.0 0.07 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF3446 PF11928.3 OAJ16821.1 - 0.25 11.5 7.9 0.11 12.7 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) RRM_1 PF00076.17 OAJ16822.1 - 9.9e-09 34.7 0.0 1.6e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ16822.1 - 7.3e-08 32.2 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ16822.1 - 0.00028 20.6 0.0 0.0005 19.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADH_zinc_N PF00107.21 OAJ16823.1 - 7.2e-20 70.8 0.0 1.3e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ16823.1 - 5.4e-07 30.5 0.0 1.3e-06 29.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 OAJ16823.1 - 0.01 15.4 0.1 0.017 14.6 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Epimerase PF01370.16 OAJ16823.1 - 0.024 14.0 0.0 0.055 12.8 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ16823.1 - 0.079 12.9 1.7 0.16 11.9 1.2 1.5 1 0 0 1 1 1 0 NADH(P)-binding Glycos_transf_1 PF00534.15 OAJ16824.1 - 3.8e-18 65.4 0.0 1.6e-12 47.2 0.0 3.0 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 OAJ16824.1 - 8e-06 25.6 0.1 0.00046 19.9 0.0 2.9 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 OAJ16824.1 - 0.004 17.3 0.1 0.027 14.6 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 OAJ16824.1 - 0.0069 16.5 2.3 0.0069 16.5 1.6 2.8 3 1 0 3 3 3 1 Glycosyl transferase 4-like domain Prenylcys_lyase PF07156.9 OAJ16826.1 - 3.5e-39 134.7 0.0 3.2e-20 72.3 0.0 2.8 2 1 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 OAJ16826.1 - 7.9e-10 38.6 0.3 4.5e-09 36.2 0.2 2.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAJ16826.1 - 2.7e-05 24.1 0.1 4.5e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ16826.1 - 4.3e-05 22.5 0.3 0.0001 21.3 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAJ16826.1 - 0.00054 19.7 0.2 0.03 14.0 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 OAJ16826.1 - 0.028 14.4 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 OAJ16826.1 - 0.03 14.0 0.3 0.059 13.0 0.2 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.19 OAJ16826.1 - 0.031 13.1 3.3 0.018 13.9 0.8 1.6 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 OAJ16826.1 - 0.034 13.2 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 OAJ16826.1 - 0.054 11.9 0.1 0.078 11.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 OAJ16826.1 - 0.077 12.0 3.5 0.12 11.4 2.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 OAJ16826.1 - 0.19 10.5 4.1 0.34 9.7 1.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A TAFII28 PF04719.9 OAJ16826.1 - 0.24 11.2 0.0 0.44 10.3 0.0 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region SEN1_N PF12726.2 OAJ16853.1 - 3.7e-67 226.9 0.4 3.5e-66 223.7 0.2 2.3 1 1 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 OAJ16853.1 - 6.3e-67 225.6 2.7 6.3e-67 225.6 1.9 2.3 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 OAJ16853.1 - 7e-60 201.8 0.0 6.8e-59 198.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 OAJ16853.1 - 3.6e-10 39.4 0.0 1.6e-09 37.3 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 OAJ16853.1 - 2.2e-05 24.1 0.0 1.2 8.6 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 OAJ16853.1 - 4.2e-05 22.9 1.3 4.2e-05 22.9 0.9 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 OAJ16853.1 - 0.0011 18.4 0.4 0.3 10.4 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 OAJ16853.1 - 0.031 14.4 0.5 0.48 10.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 OAJ16853.1 - 0.06 13.1 3.6 1 9.1 2.5 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.24 OAJ16853.1 - 0.26 11.4 3.3 0.37 10.9 0.8 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NIR_SIR PF01077.17 OAJ16854.1 - 5e-46 155.9 0.0 8.7e-38 129.1 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 OAJ16854.1 - 1.9e-28 97.8 0.0 3.6e-14 52.1 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 OAJ16854.1 - 6.4e-27 94.3 0.0 1.3e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 OAJ16854.1 - 3.5e-09 36.5 0.0 3.5e-09 36.5 0.0 2.6 3 0 0 3 3 3 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg HtaA PF04213.8 OAJ16854.1 - 0.032 14.4 0.1 0.067 13.4 0.1 1.4 1 0 0 1 1 1 0 Htaa Epimerase PF01370.16 OAJ16855.1 - 0.0005 19.5 0.0 0.51 9.7 0.0 2.2 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ16855.1 - 0.00072 19.5 0.0 0.0015 18.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding HsbA PF12296.3 OAJ16856.1 - 3.1e-05 23.8 8.0 0.026 14.3 0.0 2.5 2 1 1 3 3 3 2 Hydrophobic surface binding protein A Toprim_N PF08275.6 OAJ16857.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA primase catalytic core, N-terminal domain GST_N_3 PF13417.1 OAJ16858.1 - 1.6e-15 57.0 0.0 4.3e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAJ16858.1 - 1.3e-12 47.6 0.0 2.2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ16858.1 - 6.2e-11 42.1 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF2107 PF09880.4 OAJ16859.1 - 0.096 12.5 0.4 0.37 10.6 0.0 2.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2107) DUF1729 PF08354.5 OAJ16860.1 - 4.4e-30 103.2 1.0 9.5e-30 102.1 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Cpn60_TCP1 PF00118.19 OAJ16887.1 - 1.3e-152 508.8 0.1 2.4e-152 507.9 0.0 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1572 PF07609.6 OAJ16887.1 - 0.072 12.6 0.0 0.94 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1572) HLH PF00010.21 OAJ16889.1 - 5.5e-13 48.3 0.0 2.1e-12 46.5 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain COG5 PF10392.4 OAJ16890.1 - 0.096 12.6 2.4 13 5.7 0.6 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF4201 PF13870.1 OAJ16890.1 - 0.29 10.5 5.1 0.26 10.7 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Filament PF00038.16 OAJ16890.1 - 0.34 10.3 18.5 0.84 9.0 0.1 3.1 2 1 1 3 3 3 0 Intermediate filament protein ADIP PF11559.3 OAJ16890.1 - 0.9 9.4 8.4 0.47 10.3 1.5 3.0 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Cep57_CLD_2 PF14197.1 OAJ16890.1 - 2.2 8.2 19.3 0.095 12.6 4.2 3.4 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Myosin_tail_1 PF01576.14 OAJ16890.1 - 2.4 5.7 29.4 1 6.9 4.4 3.1 2 1 1 3 3 3 0 Myosin tail CENP-F_leu_zip PF10473.4 OAJ16890.1 - 6.7 6.5 18.6 2 8.2 0.3 3.7 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 K_oxygenase PF13434.1 OAJ16891.1 - 1.1e-06 27.7 0.0 0.015 14.2 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 OAJ16891.1 - 0.0047 17.0 0.0 25 4.8 0.0 3.7 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase TAF8_C PF10406.4 OAJ16893.1 - 6e-07 29.4 4.6 4.9e-06 26.4 2.3 2.8 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term LNS2 PF08235.8 OAJ16894.1 - 7.8e-67 223.7 0.0 6.4e-54 181.7 0.0 2.4 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 OAJ16894.1 - 5.3e-29 100.1 0.0 2.7e-19 68.8 0.0 2.4 2 0 0 2 2 2 2 lipin, N-terminal conserved region AF1Q PF15017.1 OAJ16894.1 - 0.0018 18.1 0.1 0.0075 16.1 0.0 2.0 1 0 0 1 1 1 1 Drug resistance and apoptosis regulator Acid_phosphat_B PF03767.9 OAJ16894.1 - 0.0081 15.5 0.0 0.04 13.2 0.0 2.0 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Bd3614-deam PF14439.1 OAJ16894.1 - 0.041 13.7 0.1 0.097 12.5 0.1 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase Transferase PF02458.10 OAJ16895.1 - 8.1e-09 34.4 0.0 3.5e-06 25.7 0.0 3.0 3 0 0 3 3 3 3 Transferase family XRCC1_N PF01834.11 OAJ16922.1 - 0.007 15.8 0.0 2.3 7.6 0.0 2.5 2 0 0 2 2 2 2 XRCC1 N terminal domain Herpes_U59 PF04529.7 OAJ16923.1 - 0.087 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus U59 protein 2OG-FeII_Oxy_3 PF13640.1 OAJ16925.1 - 0.00055 20.4 0.1 0.0011 19.3 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_12 PF13424.1 OAJ16926.1 - 1e-05 25.3 0.6 0.084 12.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF494 PF04361.8 OAJ16926.1 - 0.015 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF494) Imm6 PF14434.1 OAJ16926.1 - 0.02 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Immunity protein Imm6 Apc5 PF12862.2 OAJ16926.1 - 0.048 13.5 0.3 8.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 zf-RanBP PF00641.13 OAJ16928.1 - 9e-12 43.8 10.8 4e-07 29.0 0.7 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others CTDII PF01556.13 OAJ16953.1 - 3.7e-27 94.0 0.3 2.7e-18 65.6 0.0 3.4 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 OAJ16953.1 - 3.4e-22 77.9 4.4 5.5e-22 77.2 3.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 OAJ16953.1 - 1.9e-09 37.4 16.8 3.9e-09 36.4 11.1 2.0 2 0 0 2 2 2 1 DnaJ central domain Peptidase_C48 PF02902.14 OAJ16954.1 - 1.3e-25 90.2 0.0 3.8e-25 88.7 0.0 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SUR7 PF06687.7 OAJ16955.1 - 1.1e-25 90.5 2.7 1.3e-25 90.2 1.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2207 PF09972.4 OAJ16955.1 - 0.026 13.1 0.0 0.03 12.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Lig_chan PF00060.21 OAJ16955.1 - 0.059 13.0 0.4 0.12 12.0 0.1 1.6 1 1 0 1 1 1 0 Ligand-gated ion channel Amastin PF07344.6 OAJ16955.1 - 1.9 8.0 7.3 0.49 10.0 2.8 1.7 2 0 0 2 2 2 0 Amastin surface glycoprotein Cellulase PF00150.13 OAJ16957.1 - 3.4e-10 39.5 2.1 7e-10 38.5 1.4 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Zip PF02535.17 OAJ16980.1 - 3.7e-31 108.3 25.3 3.9e-30 104.9 8.4 3.9 2 2 0 3 3 3 2 ZIP Zinc transporter DUF605 PF04652.11 OAJ16980.1 - 0.0036 16.7 4.6 0.0036 16.7 3.2 2.1 1 1 0 2 2 2 1 Vta1 like FGF PF00167.13 OAJ16980.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Fibroblast growth factor PspC PF04024.7 OAJ16980.1 - 0.13 11.7 0.2 9.1 5.8 0.1 2.6 2 0 0 2 2 2 0 PspC domain ATE_C PF04377.10 OAJ16980.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, C terminus Menin PF05053.8 OAJ16980.1 - 7 4.6 5.6 13 3.8 3.9 1.4 1 0 0 1 1 1 0 Menin FH2 PF02181.18 OAJ16981.1 - 5.3e-64 216.4 3.7 5.3e-64 216.4 2.5 2.4 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 OAJ16981.1 - 1.5e-45 154.9 2.6 3.1e-45 153.8 0.0 2.8 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 OAJ16981.1 - 6e-43 146.5 0.4 5.8e-42 143.3 0.0 2.6 3 0 0 3 3 3 1 Diaphanous FH3 Domain G-gamma PF00631.17 OAJ16981.1 - 1.2 8.9 3.6 1.3 8.8 0.1 2.7 2 0 0 2 2 2 0 GGL domain TPR_11 PF13414.1 OAJ16982.1 - 3.4e-16 58.6 2.2 4.1e-12 45.5 0.3 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 OAJ16982.1 - 6.4e-08 31.9 4.9 0.078 12.9 0.1 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ16982.1 - 3.8e-07 29.4 2.3 0.11 12.2 0.1 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ16982.1 - 0.0034 17.9 3.1 0.0034 17.9 2.2 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat zf-RING_4 PF14570.1 OAJ16982.1 - 0.057 13.0 0.4 0.12 12.0 0.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TPR_12 PF13424.1 OAJ16982.1 - 0.19 11.6 5.1 1.2 9.1 0.2 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Sfi1 PF08457.5 OAJ16983.1 - 7.1e-13 47.8 80.4 6.3e-11 41.3 45.2 2.7 1 1 1 2 2 2 2 Sfi1 spindle body protein DUF4366 PF14283.1 OAJ16983.1 - 0.012 15.0 0.0 0.027 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Ebola_NP PF05505.7 OAJ16983.1 - 2.4 6.1 13.4 3.6 5.5 9.3 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Arm PF00514.18 OAJ16984.1 - 0.0012 18.5 3.6 0.13 12.1 0.1 5.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Exo_endo_phos PF03372.18 OAJ16985.1 - 7.1e-08 32.6 0.0 4.1e-07 30.1 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PFK PF00365.15 OAJ16986.1 - 3.5e-165 547.8 4.0 1.3e-97 326.1 0.3 3.2 3 0 0 3 3 3 3 Phosphofructokinase FAM216B PF15107.1 OAJ16986.1 - 0.055 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 FAM216B protein family Dimer_Tnp_hAT PF05699.9 OAJ17011.1 - 1.2e-26 92.1 0.2 1.4e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2477 PF10631.4 OAJ17013.1 - 0.053 13.7 1.3 0.099 12.8 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) TFIIA PF03153.8 OAJ17015.1 - 0.051 13.4 7.1 0.055 13.3 4.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 OAJ17015.1 - 0.14 10.3 23.9 0.16 10.1 16.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4106 PF13388.1 OAJ17015.1 - 8.9 5.1 18.0 13 4.6 12.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DBD_Tnp_Mut PF03108.10 OAJ17016.1 - 1.9e-07 30.5 0.0 3.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 MuDR family transposase MULE PF10551.4 OAJ17016.1 - 9.4e-07 28.9 0.3 2.1e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 MULE transposase domain AMP-binding PF00501.23 OAJ17017.1 - 4.9e-84 282.1 0.0 6.3e-84 281.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Collagen PF01391.13 OAJ17018.1 - 1.2e-46 156.0 258.6 1.5e-09 37.2 21.5 8.0 3 2 5 8 8 8 8 Collagen triple helix repeat (20 copies) GATase_2 PF00310.16 OAJ17049.1 - 2.3e-24 85.8 0.1 6.1e-19 67.9 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 OAJ17049.1 - 2.3e-16 59.9 0.0 5.3e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 OAJ17049.1 - 4e-14 52.4 0.5 7.5e-14 51.5 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 OAJ17049.1 - 1.6e-12 47.2 0.0 3.2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 OAJ17049.1 - 6.6e-07 28.2 0.0 1.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Histone PF00125.19 OAJ17051.1 - 1e-19 70.3 0.0 1.7e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAJ17051.1 - 1.4e-05 25.0 0.0 3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HCMVantigenic_N PF12154.3 OAJ17051.1 - 0.14 12.0 1.4 0.37 10.7 0.9 1.6 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV Daxx PF03344.10 OAJ17052.1 - 0.018 13.5 9.3 0.026 13.0 6.4 1.2 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 OAJ17052.1 - 0.18 10.4 14.0 0.28 9.8 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIF_alpha PF05793.7 OAJ17052.1 - 0.19 10.0 8.8 0.29 9.4 6.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 OAJ17052.1 - 0.25 9.2 9.4 0.31 8.9 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family Herpes_LMP1 PF05297.6 OAJ17052.1 - 0.4 9.5 3.8 0.69 8.7 2.7 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) EBV-NA3 PF05009.7 OAJ17052.1 - 1.5 7.9 5.4 2.5 7.2 3.8 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RRN3 PF05327.6 OAJ17052.1 - 2.4 6.1 4.2 3.1 5.8 2.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.7 OAJ17052.1 - 3.3 6.9 12.7 4.5 6.4 8.8 1.1 1 0 0 1 1 1 0 SDA1 Menin PF05053.8 OAJ17052.1 - 3.5 5.6 8.8 4.7 5.2 6.1 1.2 1 0 0 1 1 1 0 Menin NOA36 PF06524.7 OAJ17052.1 - 4.8 6.3 7.7 7 5.8 5.3 1.1 1 0 0 1 1 1 0 NOA36 protein DUF221 PF02714.10 OAJ17053.1 - 3.5e-84 282.4 17.3 5.1e-84 281.8 12.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAJ17053.1 - 9.5e-25 86.9 0.1 9.5e-25 86.9 0.1 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 OAJ17053.1 - 1.9e-08 34.6 0.1 4.4e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF4611 PF15387.1 OAJ17053.1 - 2 8.5 7.0 5.9 7.0 3.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) EF-hand_4 PF12763.2 OAJ17054.1 - 4.3e-34 116.3 0.0 1.1e-14 53.9 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 OAJ17054.1 - 2.2e-07 30.9 0.0 0.0029 17.6 0.0 3.9 3 1 1 4 4 4 3 EF-hand domain pair IncA PF04156.9 OAJ17054.1 - 0.0017 18.0 2.4 0.0029 17.2 1.6 1.4 1 0 0 1 1 1 1 IncA protein ATG16 PF08614.6 OAJ17054.1 - 0.0024 17.7 0.1 0.0046 16.7 0.1 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) EF-hand_1 PF00036.27 OAJ17054.1 - 0.022 14.0 4.7 2.3 7.7 0.0 4.1 5 0 0 5 5 5 0 EF hand CENP-Q PF13094.1 OAJ17054.1 - 0.025 14.5 1.1 0.046 13.7 0.8 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Reo_sigmaC PF04582.7 OAJ17054.1 - 0.096 11.8 6.8 0.15 11.2 4.7 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Fez1 PF06818.10 OAJ17054.1 - 0.38 10.7 3.5 0.57 10.1 2.4 1.2 1 0 0 1 1 1 0 Fez1 DUF4140 PF13600.1 OAJ17054.1 - 0.95 9.9 9.5 14 6.2 3.0 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2968 PF11180.3 OAJ17054.1 - 2.7 7.3 9.3 3.2 7.0 5.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Prefoldin_2 PF01920.15 OAJ17055.1 - 4.1e-18 65.0 0.3 5.7e-18 64.6 0.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF812 PF05667.6 OAJ17055.1 - 0.0024 16.4 1.0 0.0028 16.2 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Golgin_A5 PF09787.4 OAJ17055.1 - 0.0041 15.7 1.0 0.0044 15.6 0.7 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF641 PF04859.7 OAJ17055.1 - 0.087 12.5 2.1 0.63 9.7 0.6 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF3166 PF11365.3 OAJ17055.1 - 0.095 13.1 0.7 4.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) Prefoldin PF02996.12 OAJ17055.1 - 0.15 11.7 0.9 0.96 9.1 0.6 2.0 1 1 0 1 1 1 0 Prefoldin subunit Psu PF07455.6 OAJ17055.1 - 0.28 10.6 3.1 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Phage polarity suppression protein (Psu) DUF4407 PF14362.1 OAJ17055.1 - 0.57 9.0 4.6 0.82 8.5 3.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Tetraspannin PF00335.15 OAJ17056.1 - 7.2e-10 38.5 14.0 1.3e-09 37.6 9.7 1.3 1 0 0 1 1 1 1 Tetraspanin family DUF2104 PF09877.4 OAJ17056.1 - 0.07 13.1 0.6 0.14 12.1 0.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2104) FA_desaturase PF00487.19 OAJ17056.1 - 0.48 9.8 2.7 0.96 8.8 1.9 1.4 1 0 0 1 1 1 0 Fatty acid desaturase Nuc-transf PF10127.4 OAJ17077.1 - 0.072 12.4 0.1 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Predicted nucleotidyltransferase Senescence_reg PF04520.8 OAJ17079.1 - 0.39 11.2 2.2 1.1 9.8 1.5 1.9 1 1 0 1 1 1 0 Senescence regulator DNA_pol_viral_C PF00336.13 OAJ17083.1 - 0.017 14.4 0.8 0.028 13.7 0.1 1.6 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain RVT_3 PF13456.1 OAJ17083.1 - 0.033 13.9 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like zf-CCHC PF00098.18 OAJ17084.1 - 0.041 13.8 0.6 0.041 13.8 0.4 2.6 2 0 0 2 2 2 0 Zinc knuckle DUF1269 PF06897.7 OAJ17084.1 - 0.055 13.4 0.1 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Ribosomal_S14 PF00253.16 OAJ17084.1 - 1.6 8.1 5.7 11 5.4 1.8 2.6 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e LUC7 PF03194.10 OAJ17112.1 - 1.3e-72 244.3 2.5 1.3e-72 244.3 1.7 1.3 2 0 0 2 2 2 1 LUC7 N_terminus Prenyltrans PF00432.16 OAJ17113.1 - 1.8e-36 123.3 12.1 2.8e-12 45.9 0.2 5.7 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 OAJ17113.1 - 4.8e-26 91.3 1.4 1.1e-11 45.0 0.0 3.6 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 OAJ17113.1 - 2.6e-09 37.0 0.0 8.9e-05 22.4 0.0 3.3 2 1 0 2 2 2 2 Prenyltransferase-like A2M_comp PF07678.9 OAJ17113.1 - 0.018 14.3 0.0 5.6 6.1 0.0 3.6 4 1 0 5 5 5 0 A-macroglobulin complement component DUF77 PF01910.12 OAJ17114.1 - 5.4e-23 80.4 0.0 6.8e-23 80.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 OAJ17114.1 - 0.00056 20.0 0.0 0.00087 19.3 0.0 1.3 1 0 0 1 1 1 1 YKOF-related Family Ceramidase PF05875.7 OAJ17115.1 - 4.2e-65 219.4 4.3 4.9e-65 219.2 3.0 1.0 1 0 0 1 1 1 1 Ceramidase HlyIII PF03006.15 OAJ17115.1 - 0.48 9.7 12.1 3.6 6.9 8.4 2.3 1 1 0 1 1 1 0 Haemolysin-III related DASH_Dad4 PF08650.5 OAJ17116.1 - 1.3e-18 66.6 0.0 1.5e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 OAJ17116.1 - 0.011 15.4 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad1 PRMT5 PF05185.11 OAJ17117.1 - 5.7e-148 493.5 0.0 7.1e-148 493.2 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 OAJ17117.1 - 0.0065 16.9 0.0 0.021 15.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain F-box-like PF12937.2 OAJ17118.1 - 0.0067 16.1 1.3 0.43 10.3 0.1 2.6 2 0 0 2 2 2 2 F-box-like ADH_N PF08240.7 OAJ17119.1 - 1.2e-31 108.6 0.2 2.2e-31 107.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ17119.1 - 4.9e-28 97.2 0.1 7.3e-28 96.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 OAJ17119.1 - 0.0012 18.4 0.0 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 OAJ17119.1 - 0.0023 17.9 0.1 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_11 PF08241.7 OAJ17119.1 - 0.023 15.2 0.0 0.094 13.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Saccharop_dh PF03435.13 OAJ17119.1 - 0.049 12.6 0.2 0.07 12.1 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase ADH_N_assoc PF13823.1 OAJ17119.1 - 0.069 12.8 1.0 0.18 11.4 0.7 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Methyltransf_25 PF13649.1 OAJ17119.1 - 0.079 13.3 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain UPF0542 PF15086.1 OAJ17120.1 - 0.087 12.5 0.0 0.36 10.5 0.0 2.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Ssu72 PF04722.8 OAJ17122.1 - 1e-81 272.9 0.0 1.1e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein LMWPc PF01451.16 OAJ17122.1 - 0.034 14.4 0.1 0.077 13.3 0.0 1.6 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase NAD_Gly3P_dh_C PF07479.9 OAJ17122.1 - 0.12 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus DNA_repr_REX1B PF14966.1 OAJ17123.1 - 0.12 12.7 1.4 3.8 7.9 0.1 2.9 2 1 0 2 2 2 0 DNA repair REX1-B Phage_GPL PF05926.6 OAJ17123.1 - 0.9 9.3 5.3 1.8 8.4 0.8 2.3 1 1 1 2 2 2 0 Phage head completion protein (GPL) FliT PF05400.8 OAJ17123.1 - 4 7.9 13.6 0.18 12.2 5.2 1.9 2 1 1 3 3 3 0 Flagellar protein FliT Use1 PF09753.4 OAJ17123.1 - 5.3 6.3 8.0 0.19 11.1 1.5 1.6 2 0 0 2 2 2 0 Membrane fusion protein Use1 Mto2_bdg PF12808.2 OAJ17123.1 - 5.7 7.1 8.2 1 9.5 0.1 2.8 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HMG_box PF00505.14 OAJ17125.1 - 2.1e-14 53.4 1.7 2.4e-14 53.3 0.3 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ17125.1 - 8e-10 38.9 0.2 1.7e-09 37.8 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain Iso_dh PF00180.15 OAJ17148.1 - 2.7e-70 237.0 0.0 3.3e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Peptidase_M3 PF01432.15 OAJ17149.1 - 1.5e-129 432.9 0.0 2.1e-129 432.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Glycos_transf_2 PF00535.21 OAJ17150.1 - 2.8e-20 72.6 0.0 1.5e-19 70.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 OAJ17150.1 - 2.9e-07 30.5 0.2 0.00048 20.0 0.0 2.8 3 0 0 3 3 3 2 Glycosyltransferase like family 2 CDK2AP PF09806.4 OAJ17150.1 - 0.21 11.7 2.4 1.6 8.9 1.3 2.4 2 1 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Mss4 PF04421.8 OAJ17151.1 - 1.2e-10 41.0 1.3 0.00031 20.5 0.0 2.6 2 0 0 2 2 2 2 Mss4 protein Acetyltransf_1 PF00583.19 OAJ17151.1 - 0.00094 19.1 2.0 0.0019 18.1 0.0 2.5 4 0 0 4 4 4 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ17151.1 - 0.074 13.2 0.0 3.1 8.0 0.0 2.8 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain SHR3_chaperone PF08229.6 OAJ17152.1 - 1.9e-22 79.2 0.0 4e-22 78.1 0.0 1.5 1 1 0 1 1 1 1 ER membrane protein SH3 Med21 PF11221.3 OAJ17152.1 - 0.095 12.6 2.9 0.16 11.9 2.0 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex SecG PF03840.9 OAJ17152.1 - 7 6.4 8.6 0.23 11.2 0.5 2.4 2 0 0 2 2 2 0 Preprotein translocase SecG subunit DUF676 PF05057.9 OAJ17153.1 - 2.2e-29 102.3 0.0 4e-24 85.1 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 OAJ17153.1 - 0.0019 17.9 0.0 0.006 16.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ17153.1 - 0.038 13.8 1.6 0.69 9.7 1.1 2.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family RVT_1 PF00078.22 OAJ17154.1 - 1.8e-12 47.0 0.0 2.6e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SNF2_N PF00176.18 OAJ17155.1 - 7.7e-68 228.4 0.0 2.6e-66 223.4 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ17155.1 - 6.4e-17 61.1 0.0 4.6e-16 58.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 OAJ17155.1 - 2.7e-08 33.0 0.3 9.4e-07 27.9 0.0 2.8 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 OAJ17155.1 - 2.8e-06 27.2 0.0 1.7e-05 24.7 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF676 PF05057.9 OAJ17156.1 - 8.2e-27 93.9 0.0 1.6e-21 76.6 0.0 2.3 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 OAJ17156.1 - 0.00035 20.3 0.0 0.00064 19.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAJ17156.1 - 0.0025 17.4 0.1 0.0049 16.4 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 OAJ17156.1 - 0.004 17.0 0.5 0.0081 16.0 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Sarcoglycan_2 PF05510.8 OAJ17156.1 - 0.019 13.2 0.0 0.076 11.2 0.0 1.8 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon Lipase_3 PF01764.20 OAJ17156.1 - 0.057 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2235 PF09994.4 OAJ17156.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) NUC173 PF08161.7 OAJ17179.1 - 5.2e-39 133.6 0.0 8.4e-38 129.7 0.0 2.6 1 1 0 1 1 1 1 NUC173 domain CAS_CSE1 PF03378.10 OAJ17179.1 - 0.21 9.8 0.0 0.53 8.5 0.0 1.6 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus CDC73 PF05179.9 OAJ17180.1 - 3.2e-42 144.7 1.1 2.1e-30 106.0 0.7 2.4 2 0 0 2 2 2 2 RNA pol II accessory factor, Cdc73 family DUF1436 PF07262.6 OAJ17180.1 - 0.23 10.9 0.0 0.86 9.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1436) HMGL-like PF00682.14 OAJ17181.1 - 6.3e-72 242.0 0.5 1.1e-71 241.2 0.2 1.5 2 0 0 2 2 2 1 HMGL-like PAN_4 PF14295.1 OAJ17182.1 - 0.45 10.2 5.8 0.34 10.6 1.9 2.0 1 1 1 2 2 2 0 PAN domain N_methyl_3 PF13633.1 OAJ17182.1 - 0.5 10.3 3.6 0.67 9.9 2.5 1.2 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation site Utp14 PF04615.8 OAJ17183.1 - 1e-147 493.4 34.4 1e-147 493.4 23.9 3.0 2 1 1 3 3 3 1 Utp14 protein UPF0113 PF03657.8 OAJ17184.1 - 1.5e-11 44.2 0.0 2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PI3_PI4_kinase PF00454.22 OAJ17185.1 - 9.1e-33 113.6 0.0 5.5e-32 111.1 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 OAJ17185.1 - 9.4e-26 90.1 0.2 3.3e-25 88.3 0.0 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Ipi1_N PF12333.3 OAJ17185.1 - 0.022 14.7 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Thioredoxin PF00085.15 OAJ17210.1 - 1.7e-20 72.6 0.0 2.2e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 OAJ17210.1 - 0.00018 21.6 0.1 0.00037 20.6 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAJ17210.1 - 0.004 17.2 0.5 0.025 14.6 0.0 2.2 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 OAJ17210.1 - 0.012 15.6 0.1 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_4 PF13462.1 OAJ17210.1 - 0.017 15.1 0.4 0.052 13.5 0.3 1.7 1 1 1 2 2 2 0 Thioredoxin Ribosomal_L34e PF01199.13 OAJ17211.1 - 2.2e-37 127.1 4.4 2.8e-37 126.8 3.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e Cytochrome_C7 PF14522.1 OAJ17211.1 - 0.0049 16.4 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c7 FhuF_C PF11575.3 OAJ17211.1 - 0.23 11.1 2.0 8.1 6.1 0.1 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain DAGK_cat PF00781.19 OAJ17212.1 - 4.2e-21 74.7 0.1 8e-21 73.8 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Antimicrobial_5 PF08026.6 OAJ17212.1 - 0.048 13.5 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 Bee antimicrobial peptide TFIIF_alpha PF05793.7 OAJ17213.1 - 0.00039 18.9 0.0 0.00039 18.9 0.0 5.1 4 1 0 4 4 4 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) cwf18 PF08315.7 OAJ17214.1 - 0.71 10.3 17.3 5.3 7.5 8.3 2.4 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor Suf PF05843.9 OAJ17214.1 - 3.8 7.1 28.2 0.69 9.5 14.3 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RR_TM4-6 PF06459.7 OAJ17214.1 - 4.4 7.1 21.6 0.35 10.7 7.7 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Gtr1_RagA PF04670.7 OAJ17215.1 - 6e-35 120.4 0.0 8.1e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 OAJ17215.1 - 0.00093 18.9 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase MMR_HSR1 PF01926.18 OAJ17215.1 - 0.0025 17.7 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAJ17215.1 - 0.007 16.8 0.0 0.021 15.3 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 OAJ17215.1 - 0.017 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 OAJ17215.1 - 0.021 14.7 0.0 0.053 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 OAJ17215.1 - 0.043 13.0 0.0 0.22 10.7 0.0 2.1 1 1 0 1 1 1 0 ADP-ribosylation factor family RRM_1 PF00076.17 OAJ17216.1 - 1.4e-10 40.6 0.0 0.00022 20.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ17216.1 - 2.2e-10 40.3 0.0 0.00031 20.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.8 OAJ17216.1 - 0.0035 17.2 25.1 0.039 13.8 9.6 2.5 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Cuticle_1 PF08140.6 OAJ17216.1 - 0.043 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Lactamase_B_2 PF12706.2 OAJ17217.1 - 1.7e-25 89.7 0.0 5.2e-24 84.8 0.0 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 OAJ17217.1 - 7.1e-08 32.3 0.0 1.4e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain GAPT PF11770.3 OAJ17218.1 - 0.24 11.0 0.2 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) tRNA-synt_1g PF09334.6 OAJ17246.1 - 3e-144 480.4 0.0 3.8e-144 480.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 OAJ17246.1 - 8.5e-09 33.9 0.5 4.7e-05 21.6 0.0 3.4 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) WHEP-TRS PF00458.15 OAJ17246.1 - 1.1e-06 28.2 2.9 1.1e-06 28.2 2.0 2.1 2 0 0 2 2 2 1 WHEP-TRS domain DZR PF12773.2 OAJ17246.1 - 0.043 13.6 3.5 0.094 12.5 2.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon DUF2201_N PF13203.1 OAJ17246.1 - 0.18 10.9 5.5 0.31 10.1 3.8 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Brix PF04427.13 OAJ17247.1 - 2.8e-38 131.5 0.0 4e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain FHA PF00498.21 OAJ17250.1 - 0.042 13.9 0.0 0.097 12.7 0.0 1.7 2 0 0 2 2 2 0 FHA domain PPR PF01535.15 OAJ17251.1 - 1.2e-06 28.0 0.0 0.29 11.1 0.0 4.3 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.1 OAJ17251.1 - 3.6e-06 26.8 0.2 0.12 12.7 0.0 4.2 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 OAJ17251.1 - 2e-05 24.4 0.0 1.2 9.1 0.0 5.0 5 0 0 5 5 5 1 PPR repeat family PPR_1 PF12854.2 OAJ17251.1 - 0.0018 17.7 0.3 0.032 13.6 0.0 2.5 2 0 0 2 2 2 1 PPR repeat MscS_porin PF12795.2 OAJ17252.1 - 0.011 15.0 0.4 0.011 15.0 0.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain ADIP PF11559.3 OAJ17252.1 - 0.027 14.3 0.5 0.028 14.3 0.3 1.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.4 OAJ17252.1 - 0.029 12.9 0.4 0.028 12.9 0.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3391 PF11871.3 OAJ17252.1 - 0.042 14.0 0.1 0.05 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Acyl-CoA_dh_2 PF08028.6 OAJ17252.1 - 0.11 12.7 0.7 0.12 12.6 0.5 1.1 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Sugarporin_N PF11471.3 OAJ17252.1 - 0.51 10.0 3.5 0.57 9.8 0.6 1.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension UBX PF00789.15 OAJ17280.1 - 3.3e-05 23.8 0.0 0.00013 21.9 0.0 2.0 2 0 0 2 2 2 1 UBX domain UBA PF00627.26 OAJ17280.1 - 0.0053 16.5 0.1 0.24 11.3 0.0 3.2 3 0 0 3 3 3 1 UBA/TS-N domain zf-C2H2 PF00096.21 OAJ17280.1 - 0.073 13.4 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zinc_ribbon_4 PF13717.1 OAJ17280.1 - 0.098 12.3 0.1 0.28 10.8 0.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain Rtf2 PF04641.7 OAJ17280.1 - 0.11 11.7 20.9 0.18 10.9 14.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zinc_ribbon_5 PF13719.1 OAJ17280.1 - 0.11 12.0 0.4 0.31 10.6 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain DUF572 PF04502.8 OAJ17280.1 - 0.13 11.4 22.8 0.18 11.0 15.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Asp-B-Hydro_N PF05279.6 OAJ17280.1 - 1.4 8.6 23.0 2.1 8.1 16.0 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PLRV_ORF5 PF01690.12 OAJ17280.1 - 1.8 7.6 11.0 2.2 7.3 7.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein zf-C2H2_2 PF12756.2 OAJ17280.1 - 2.1 8.4 7.0 0.3 11.1 0.2 2.4 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Peptidase_S49_N PF08496.5 OAJ17280.1 - 3.8 7.2 20.1 0.43 10.3 4.6 2.2 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Hex_IIIa PF02455.11 OAJ17280.1 - 4 6.0 8.9 5.8 5.4 6.1 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Lipoprotein_X PF03305.8 OAJ17280.1 - 9.7 5.4 9.3 15 4.8 6.5 1.2 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein SKN1 PF03935.10 OAJ17281.1 - 3.7e-174 579.5 2.7 4.3e-174 579.3 1.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Aminotran_1_2 PF00155.16 OAJ17282.1 - 2e-40 138.8 0.0 3.6e-40 138.0 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 OAJ17282.1 - 0.00046 18.5 0.0 0.00097 17.5 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Fasciclin PF02469.17 OAJ17283.1 - 6.9e-39 132.7 0.0 3.5e-08 33.4 0.0 6.5 5 2 0 5 5 5 5 Fasciclin domain E1-E2_ATPase PF00122.15 OAJ17284.1 - 3.2e-65 219.3 3.1 3.2e-65 219.3 2.2 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAJ17284.1 - 5.7e-35 120.4 2.7 5.7e-35 120.4 1.9 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ17284.1 - 3.8e-30 105.9 0.0 1.3e-28 100.8 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ17284.1 - 1.9e-17 62.9 0.0 3.8e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 OAJ17284.1 - 1.2e-14 53.5 0.0 1.2e-14 53.5 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 OAJ17284.1 - 3e-12 47.1 0.1 9.1e-12 45.5 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ17284.1 - 3e-07 30.3 0.1 1.1e-05 25.2 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.4 OAJ17284.1 - 9.2 4.7 8.0 2.3 6.7 0.1 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Tyr_Deacylase PF02580.11 OAJ17285.1 - 6e-46 156.0 0.3 7.8e-45 152.4 0.2 1.9 1 1 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Sec16_C PF12931.2 OAJ17286.1 - 2.8e-71 240.5 0.0 6.2e-71 239.4 0.0 1.6 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 OAJ17286.1 - 5.2e-21 74.8 0.0 1.1e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region BAR_2 PF10455.4 OAJ17287.1 - 1.2e-41 142.5 0.0 3.6e-41 140.9 0.0 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 OAJ17287.1 - 8.4e-13 48.3 0.5 1.5e-10 41.0 0.1 2.1 2 0 0 2 2 2 2 BAR domain ATG16 PF08614.6 OAJ17287.1 - 0.0048 16.7 1.9 0.27 11.0 0.6 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Phycobilisome PF00502.14 OAJ17287.1 - 0.069 12.9 1.0 2.3 7.9 0.0 2.5 1 1 0 2 2 2 0 Phycobilisome protein Uds1 PF15456.1 OAJ17287.1 - 0.37 10.7 7.8 0.89 9.5 0.1 2.9 2 1 1 3 3 3 0 Up-regulated During Septation Seryl_tRNA_N PF02403.17 OAJ17287.1 - 0.51 10.3 0.0 0.51 10.3 0.0 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1090 PF06476.7 OAJ17287.1 - 3 7.5 9.0 0.22 11.1 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DUF4112 PF13430.1 OAJ17288.1 - 6.8e-28 96.6 0.1 9e-28 96.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Asp PF00026.18 OAJ17315.1 - 1.3e-07 31.2 0.0 1.7e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 OAJ17315.1 - 0.022 14.3 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DUF4175 PF13779.1 OAJ17316.1 - 2 6.0 16.1 2.2 5.8 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3432 PF11914.3 OAJ17316.1 - 5.8 7.0 18.8 9.4 6.3 13.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) DUF605 PF04652.11 OAJ17316.1 - 5.9 6.1 20.3 8.3 5.6 14.1 1.1 1 0 0 1 1 1 0 Vta1 like F-box-like PF12937.2 OAJ17317.1 - 1.3e-14 53.6 5.0 4.7e-14 51.8 0.1 2.9 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 OAJ17317.1 - 1.5e-10 40.4 3.3 3.3e-10 39.3 0.1 2.7 3 0 0 3 3 3 1 F-box domain RXT2_N PF08595.6 OAJ17317.1 - 0.25 11.1 4.9 19 5.0 0.0 2.1 1 1 1 2 2 2 0 RXT2-like, N-terminal Abi PF02517.11 OAJ17318.1 - 2e-15 56.6 4.7 2e-15 56.6 3.3 2.6 3 1 0 3 3 3 1 CAAX protease self-immunity PCI PF01399.22 OAJ17319.1 - 9.8e-08 32.2 0.1 2.8e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 PCI domain START PF01852.14 OAJ17320.1 - 0.00099 18.4 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 START domain F-box-like PF12937.2 OAJ17321.1 - 4.3e-05 23.1 0.5 0.00039 20.0 0.4 2.3 1 1 0 1 1 1 1 F-box-like PALP PF00291.20 OAJ17322.1 - 2.2e-42 145.3 0.0 3.4e-40 138.1 0.0 2.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1049 PF06305.6 OAJ17322.1 - 0.0043 16.4 1.5 0.037 13.5 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1049) ADH_zinc_N PF00107.21 OAJ17322.1 - 0.053 13.0 0.0 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Tim17 PF02466.14 OAJ17322.1 - 0.18 11.8 2.4 12 5.9 0.2 2.3 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Ribonuclease_3 PF00636.21 OAJ17323.1 - 9.2e-38 129.1 0.0 2.9e-19 69.6 0.0 3.0 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 OAJ17323.1 - 1.4e-20 73.5 6.1 3.3e-12 46.4 0.2 3.7 3 1 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.26 OAJ17323.1 - 5.3e-14 51.8 0.0 1.4e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 OAJ17323.1 - 1.1e-12 47.4 0.1 3.1e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.24 OAJ17323.1 - 5.1e-08 32.5 0.0 1.3e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ17323.1 - 7.6e-08 32.3 0.0 2e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 OAJ17323.1 - 0.0036 17.8 0.0 0.04 14.4 0.0 2.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif SNF2_N PF00176.18 OAJ17323.1 - 0.051 12.3 0.0 0.12 11.1 0.0 1.6 1 0 0 1 1 1 0 SNF2 family N-terminal domain p450 PF00067.17 OAJ17324.1 - 2e-35 122.2 0.0 1.7e-17 63.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Inositol_P PF00459.20 OAJ17325.1 - 1.8e-60 204.5 0.0 2.1e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family OAD_gamma PF04277.8 OAJ17348.1 - 0.022 15.1 1.0 9.4 6.6 0.0 2.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Nucleoplasmin PF03066.10 OAJ17348.1 - 0.26 10.8 4.1 0.43 10.0 2.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin rve PF00665.21 OAJ17349.1 - 0.00062 19.8 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.1 OAJ17349.1 - 0.0067 16.0 0.1 0.024 14.2 0.0 2.0 1 0 0 1 1 1 1 Homeodomain-like domain CPSase_L_D3 PF02787.14 OAJ17349.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ScpA_ScpB PF02616.9 OAJ17349.1 - 0.12 11.9 0.0 2.7 7.4 0.0 2.1 2 0 0 2 2 2 0 ScpA/B protein Rubredoxin PF00301.15 OAJ17350.1 - 0.09 12.6 1.9 0.17 11.8 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin Amino_oxidase PF01593.19 OAJ17351.1 - 6.2e-58 196.9 0.1 1.8e-57 195.4 0.1 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAJ17351.1 - 2.7e-08 33.7 3.4 2.3e-07 30.7 2.4 2.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ17351.1 - 5.3e-07 28.8 2.1 4.9e-06 25.6 1.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAJ17351.1 - 0.0038 17.1 0.1 0.029 14.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAJ17351.1 - 0.0064 15.3 1.3 0.016 14.0 0.9 1.7 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 OAJ17351.1 - 0.0089 16.1 0.1 0.03 14.3 0.1 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ17351.1 - 0.039 13.0 0.1 0.078 12.0 0.1 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 OAJ17351.1 - 0.046 12.7 0.2 0.74 8.7 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 OAJ17351.1 - 0.07 13.5 0.1 22 5.5 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAJ17351.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 OAJ17351.1 - 0.26 9.7 0.1 3 6.2 0.0 2.6 4 0 0 4 4 4 0 HI0933-like protein MFS_1 PF07690.11 OAJ17353.1 - 4.9e-33 114.3 37.4 7.9e-33 113.6 25.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 OAJ17353.1 - 0.0071 14.4 1.0 0.016 13.2 0.7 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_32N PF00251.15 OAJ17354.1 - 4.2e-23 82.1 0.0 9.6e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 OAJ17354.1 - 2.9e-05 24.3 0.0 5.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 OAJ17354.1 - 0.073 12.9 1.7 0.48 10.4 0.0 3.2 2 0 0 2 2 2 0 BNR/Asp-box repeat Utp11 PF03998.8 OAJ17355.1 - 2.5e-50 171.6 12.9 4.8e-50 170.6 8.9 1.5 1 1 0 1 1 1 1 Utp11 protein Syntaxin_2 PF14523.1 OAJ17355.1 - 0.0086 16.0 2.1 0.14 12.2 0.0 2.7 3 0 0 3 3 3 1 Syntaxin-like protein Flu_NS2 PF00601.14 OAJ17355.1 - 0.12 12.5 0.7 10 6.4 0.1 2.5 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) ABC1 PF03109.11 OAJ17356.1 - 3.8e-22 78.4 0.0 3.8e-14 52.6 0.0 2.4 2 0 0 2 2 2 2 ABC1 family Pkinase PF00069.20 OAJ17357.1 - 1.4e-18 66.9 0.0 3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ17357.1 - 3.2e-12 46.0 0.0 8.9e-12 44.6 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ17357.1 - 0.18 10.7 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF1880 PF08976.6 OAJ17357.1 - 0.59 10.2 3.9 1.8 8.6 2.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1880) Peptidase_S9 PF00326.16 OAJ17358.1 - 2.2e-32 111.9 0.0 6e-32 110.6 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 OAJ17358.1 - 4.6e-12 46.3 0.1 9.3e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ17358.1 - 8.8e-11 41.7 0.0 2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 OAJ17358.1 - 5.2e-05 23.0 0.0 0.00013 21.6 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 OAJ17358.1 - 0.00036 19.8 0.0 0.0026 17.0 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.7 OAJ17358.1 - 0.0014 17.1 0.0 0.0021 16.6 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 OAJ17358.1 - 0.0052 16.3 0.1 0.036 13.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 OAJ17358.1 - 0.055 12.8 0.0 2.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pyr_redox_2 PF07992.9 OAJ17384.1 - 1.4e-19 70.8 0.0 2.4e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ17384.1 - 3.1e-13 49.9 0.1 1.8e-09 37.8 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 OAJ17384.1 - 2.1e-08 32.8 4.0 4.7e-05 22.3 0.9 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 OAJ17384.1 - 3.1e-07 30.4 3.1 1.1e-06 28.6 2.3 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 OAJ17384.1 - 3.5e-07 29.5 2.8 0.00033 20.2 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 OAJ17384.1 - 1.6e-06 27.1 3.9 0.0014 17.9 0.7 2.4 2 0 0 2 2 2 2 EF hand NAD_binding_7 PF13241.1 OAJ17384.1 - 0.0055 16.9 0.5 2.5 8.4 0.0 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding EF-hand_8 PF13833.1 OAJ17384.1 - 0.0099 15.4 5.1 1.4 8.6 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair Mito_fiss_reg PF05308.6 OAJ17384.1 - 0.078 12.3 1.8 0.14 11.5 1.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator SPARC_Ca_bdg PF10591.4 OAJ17384.1 - 0.12 12.3 1.8 1.2 9.1 0.2 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region P21-Arc PF04062.9 OAJ17385.1 - 1.2e-76 256.3 0.0 1.4e-76 256.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit vATP-synt_E PF01991.13 OAJ17386.1 - 8.1e-58 194.9 13.9 9.4e-58 194.7 9.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF3355 PF11835.3 OAJ17386.1 - 0.14 11.9 1.5 0.25 11.1 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3355) zf-RING_2 PF13639.1 OAJ17388.1 - 9.5e-15 54.1 4.3 2.2e-14 53.0 3.0 1.6 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 OAJ17388.1 - 8.6e-09 35.0 0.0 5.8e-07 29.1 0.0 2.7 2 0 0 2 2 2 1 PA domain zf-C3HC4_2 PF13923.1 OAJ17388.1 - 1.9e-08 34.1 3.4 4e-08 33.1 2.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ17388.1 - 9.4e-06 25.2 2.1 1.8e-05 24.3 1.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 OAJ17388.1 - 1.3e-05 25.2 0.5 2.8e-05 24.1 0.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 OAJ17388.1 - 2.5e-05 23.8 1.7 5e-05 22.8 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ17388.1 - 5.5e-05 22.7 5.5 0.00013 21.5 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAJ17388.1 - 0.032 14.0 1.9 0.083 12.7 1.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 OAJ17388.1 - 0.083 12.6 2.7 0.33 10.6 1.2 2.5 2 1 1 3 3 3 0 RING-type zinc-finger zf-Nse PF11789.3 OAJ17388.1 - 0.19 11.2 1.1 0.38 10.3 0.5 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 OAJ17388.1 - 1.4 8.9 3.8 5.8 6.9 2.6 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain PP2C PF00481.16 OAJ17389.1 - 1.1e-27 97.0 0.0 3.6e-26 92.0 0.0 2.6 2 1 0 2 2 2 1 Protein phosphatase 2C Ribosomal_60s PF00428.14 OAJ17389.1 - 1 9.8 6.6 0.34 11.3 0.7 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein LRR_4 PF12799.2 OAJ17391.1 - 5.9e-06 25.7 0.0 9.1 6.0 0.0 5.3 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) F-box-like PF12937.2 OAJ17391.1 - 1.1e-05 25.0 3.8 2.4e-05 23.9 1.9 2.3 2 0 0 2 2 2 1 F-box-like CRAL_TRIO PF00650.15 OAJ17392.1 - 8.4e-36 122.8 0.1 1.4e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ17392.1 - 3.5e-13 49.4 0.9 3.5e-13 49.4 0.6 2.3 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Ras PF00071.17 OAJ17420.1 - 1e-53 181.0 0.0 1.2e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ17420.1 - 6.5e-17 62.1 0.0 8.4e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ17420.1 - 6e-06 25.6 0.0 9e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ17420.1 - 0.0015 17.9 0.0 0.018 14.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF367 PF04034.8 OAJ17421.1 - 7.5e-42 141.9 0.0 1e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 OAJ17421.1 - 1.2e-13 50.3 0.1 2.3e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SDA1 PF05285.7 OAJ17421.1 - 1.7 7.8 19.1 10 5.2 10.4 2.1 2 0 0 2 2 2 0 SDA1 DUF2201_N PF13203.1 OAJ17421.1 - 7.7 5.5 11.5 4.4 6.3 5.0 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain ICL PF00463.16 OAJ17422.1 - 3.7e-254 843.7 1.5 4.2e-254 843.6 1.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 OAJ17422.1 - 1.2e-09 37.7 0.0 2.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 OAJ17422.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Mad3_BUB1_I PF08311.7 OAJ17423.1 - 1.7e-32 111.8 0.2 2.8e-32 111.1 0.2 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 OAJ17423.1 - 1.3e-11 44.2 0.0 2.6e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ17423.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Translin PF01997.11 OAJ17424.1 - 6.4e-41 140.1 0.2 8.2e-41 139.8 0.1 1.1 1 0 0 1 1 1 1 Translin family BLOC1_2 PF10046.4 OAJ17424.1 - 0.02 15.0 0.1 0.46 10.6 0.0 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EST1_DNA_bind PF10373.4 OAJ17425.1 - 1.3e-31 109.8 0.0 1.2e-30 106.7 0.0 2.4 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 OAJ17425.1 - 1.5e-07 31.4 0.0 8.6e-07 29.0 0.0 2.3 2 1 0 2 2 2 1 Telomerase activating protein Est1 TPR_11 PF13414.1 OAJ17425.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 TPR repeat Secretin_N_2 PF07655.8 OAJ17425.1 - 0.036 14.4 0.3 0.036 14.4 0.2 3.6 4 0 0 4 4 4 0 Secretin N-terminal domain CDP-OH_P_transf PF01066.16 OAJ17426.1 - 2.1e-16 60.0 3.6 2.3e-16 59.9 2.0 1.5 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase NAD_binding_11 PF14833.1 OAJ17427.1 - 4.7e-32 110.6 0.1 9.6e-32 109.6 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 OAJ17427.1 - 1.9e-30 105.8 0.0 4.2e-30 104.7 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 OAJ17427.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Cellulase PF00150.13 OAJ17429.1 - 5.4e-18 65.1 5.0 1.6e-17 63.6 3.5 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MDMPI_C PF07398.6 OAJ17455.1 - 0.19 12.3 0.2 0.19 12.3 0.1 3.2 4 1 0 4 4 4 0 MDMPI C-terminal domain Acyltransferase PF01553.16 OAJ17456.1 - 1e-16 60.5 0.1 1.6e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase Tic20 PF09685.5 OAJ17456.1 - 0.13 12.2 2.0 0.31 11.0 1.4 1.6 1 0 0 1 1 1 0 Tic20-like protein Peptidase_M20 PF01546.23 OAJ17457.1 - 1.5e-18 66.9 4.0 6.6e-18 64.8 2.8 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 OAJ17457.1 - 1.7e-15 56.1 17.0 7.3e-07 28.8 0.0 7.9 8 1 1 9 9 9 4 WD domain, G-beta repeat M20_dimer PF07687.9 OAJ17457.1 - 4e-09 36.2 0.0 9.3e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain TACI-CRD2 PF09305.5 OAJ17457.1 - 0.055 13.2 0.2 5 7.0 0.0 2.6 2 0 0 2 2 2 0 TACI, cysteine-rich domain VIT1 PF01988.14 OAJ17458.1 - 1.4e-64 217.5 5.9 1.9e-64 217.0 4.1 1.2 1 0 0 1 1 1 1 VIT family KAR9 PF08580.5 OAJ17459.1 - 7.8e-05 21.1 0.8 7.8e-05 21.1 0.5 4.0 2 2 1 3 3 3 1 Yeast cortical protein KAR9 GAS2 PF02187.12 OAJ17459.1 - 0.075 12.8 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain IF4E PF01652.13 OAJ17461.1 - 2.7e-46 157.0 0.0 4.5e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Cation_efflux PF01545.16 OAJ17461.1 - 6.4e-39 133.7 11.7 1.8e-38 132.2 8.1 1.8 1 1 0 1 1 1 1 Cation efflux family LEA_2 PF03168.8 OAJ17462.1 - 0.0082 16.5 0.0 0.025 14.9 0.0 1.9 1 1 1 2 2 2 1 Late embryogenesis abundant protein Cellulase PF00150.13 OAJ17463.1 - 5.1e-09 35.7 0.0 7.3e-08 31.9 0.0 2.4 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Apolipoprotein PF01442.13 OAJ17494.1 - 0.013 14.9 2.0 0.018 14.5 1.4 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain RNF111_N PF15303.1 OAJ17494.1 - 0.047 13.2 0.6 0.047 13.2 0.4 1.6 1 1 1 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus ROF PF07073.7 OAJ17494.1 - 0.064 13.2 0.6 0.15 12.0 0.4 1.6 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) MFS_1 PF07690.11 OAJ17495.1 - 6.8e-42 143.4 49.5 6.8e-42 143.4 34.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ17495.1 - 1.2e-11 43.8 9.7 1.2e-11 43.8 6.7 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter PS_Dcarbxylase PF02666.10 OAJ17496.1 - 1.2e-47 161.8 0.0 2.6e-47 160.7 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase C2 PF00168.25 OAJ17496.1 - 6.3e-29 99.6 0.0 2.5e-14 52.8 0.0 3.6 3 0 0 3 3 3 3 C2 domain SDA1 PF05285.7 OAJ17496.1 - 0.37 10.0 17.8 0.25 10.5 9.8 2.2 2 0 0 2 2 2 0 SDA1 Daxx PF03344.10 OAJ17496.1 - 1.8 6.9 17.9 0.021 13.3 6.5 1.9 2 0 0 2 2 2 0 Daxx Family RVT_2 PF07727.9 OAJ17498.1 - 2.9e-78 262.2 0.0 4.1e-78 261.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ17498.1 - 6.9e-24 84.2 0.1 3.7e-23 81.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ17498.1 - 7e-07 28.7 0.0 1e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ17498.1 - 0.055 13.0 0.1 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain UBN2 PF14223.1 OAJ17499.1 - 1.3e-14 53.9 0.1 2.8e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAJ17499.1 - 2.2e-10 40.1 0.0 3.9e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 OAJ17499.1 - 1.4e-08 34.6 0.1 3.5e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAJ17499.1 - 0.31 11.0 2.8 0.58 10.2 2.0 1.5 1 0 0 1 1 1 0 Zinc knuckle SpoIIE PF07228.7 OAJ17530.1 - 5.9e-08 32.6 0.0 0.019 14.6 0.0 3.3 3 0 0 3 3 3 3 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 OAJ17530.1 - 5.5e-06 25.9 0.5 0.11 11.8 0.1 2.9 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C PF00481.16 OAJ17530.1 - 1.9e-05 24.1 0.0 0.00041 19.8 0.0 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C zf-CCHC PF00098.18 OAJ17532.1 - 0.00061 19.5 5.7 0.001 18.8 3.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ17532.1 - 0.0014 18.3 1.2 0.0027 17.3 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 OAJ17532.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.1 OAJ17532.1 - 0.073 12.5 2.2 0.13 11.7 1.5 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 OAJ17532.1 - 2.2 7.8 10.7 0.35 10.3 4.5 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RVT_2 PF07727.9 OAJ17533.1 - 2.3e-88 295.3 0.0 3.4e-88 294.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ17533.1 - 8.8e-26 90.3 0.0 2.3e-25 89.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ17533.1 - 1.2e-05 24.6 0.0 4.4e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ17533.1 - 4.6e-05 22.9 0.4 0.0001 21.8 0.3 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain TPR_11 PF13414.1 OAJ17534.1 - 1e-47 159.6 33.1 3.3e-13 49.0 4.9 7.5 3 3 5 8 8 8 8 TPR repeat TPR_2 PF07719.12 OAJ17534.1 - 3.9e-30 101.3 21.6 1.9e-05 24.2 0.0 11.0 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ17534.1 - 7.6e-30 101.2 20.9 2e-06 27.1 0.8 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ17534.1 - 2.6e-27 94.8 12.8 3.4e-07 30.7 0.0 6.4 4 2 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ17534.1 - 7.1e-23 78.8 14.0 1.4e-05 24.8 0.0 9.2 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ17534.1 - 4.1e-20 71.5 18.4 5e-06 26.3 0.0 7.1 3 2 7 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ17534.1 - 5.1e-15 54.0 16.8 0.0016 18.1 0.2 8.8 8 2 1 9 9 8 4 Tetratricopeptide repeat Apc3 PF12895.2 OAJ17534.1 - 8e-15 54.7 11.5 0.00018 21.5 0.1 5.0 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 OAJ17534.1 - 5.1e-14 51.5 16.6 0.002 18.6 0.0 9.2 4 4 6 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ17534.1 - 3.3e-13 49.7 19.5 0.00024 21.3 0.0 6.2 4 1 3 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ17534.1 - 2e-09 37.1 11.9 1.5e-05 24.7 0.1 5.5 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ17534.1 - 3.6e-07 29.4 16.7 0.44 10.4 0.0 7.7 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 OAJ17534.1 - 1.5e-05 24.1 11.4 0.021 13.9 1.4 4.3 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ17534.1 - 7.9e-05 22.7 11.2 0.036 14.1 0.0 5.5 3 2 4 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ17534.1 - 0.00097 19.4 23.6 0.44 11.1 0.0 8.1 10 0 0 10 10 6 3 Tetratricopeptide repeat DUF3856 PF12968.2 OAJ17534.1 - 0.012 15.4 11.1 0.35 10.6 0.0 5.4 4 2 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.9 OAJ17534.1 - 0.015 15.6 1.2 20 5.9 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 OAJ17534.1 - 0.059 13.1 0.3 1.6 8.5 0.0 3.2 4 0 0 4 4 3 0 Rapsyn N-terminal myristoylation and linker region TPR_10 PF13374.1 OAJ17534.1 - 0.16 11.9 17.0 6.2 6.8 0.0 7.2 6 1 1 7 7 7 0 Tetratricopeptide repeat Methyltransf_2 PF00891.13 OAJ17535.1 - 2.3e-31 108.8 0.0 6.8e-28 97.4 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase Methyltransf_18 PF12847.2 OAJ17535.1 - 0.0027 18.2 0.0 0.006 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain tRNA-synt_1b PF00579.20 OAJ17536.1 - 3e-59 200.5 0.0 8.9e-59 198.9 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) MSP1_C PF07462.6 OAJ17536.1 - 1.8 6.8 6.6 3.8 5.8 4.6 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Rad60-SLD PF11976.3 OAJ17537.1 - 1.2e-23 82.5 0.2 1.5e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 OAJ17537.1 - 7.6e-10 38.0 0.0 9.6e-10 37.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family GTP_EFTU PF00009.22 OAJ17538.1 - 5.1e-55 185.8 0.0 1e-54 184.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 OAJ17538.1 - 4.9e-35 119.6 0.1 1.5e-34 118.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 OAJ17538.1 - 5.8e-29 99.7 0.0 1.3e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 OAJ17538.1 - 3e-22 78.3 0.1 7.7e-22 76.9 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 OAJ17538.1 - 3.1e-12 46.4 0.0 9.1e-12 44.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PPR_2 PF13041.1 OAJ17539.1 - 9.4e-30 102.3 0.4 1.4e-07 31.4 0.0 8.6 4 1 6 10 10 10 6 PPR repeat family PPR_3 PF13812.1 OAJ17539.1 - 1e-21 75.2 5.2 0.0064 16.6 0.0 10.9 11 0 0 11 11 11 4 Pentatricopeptide repeat domain PPR PF01535.15 OAJ17539.1 - 5e-21 73.1 1.6 0.0077 16.1 0.0 9.5 12 1 0 12 12 12 4 PPR repeat PPR_1 PF12854.2 OAJ17539.1 - 1.4e-11 43.6 5.1 0.00058 19.2 0.0 6.7 7 1 0 7 7 7 3 PPR repeat TPR_14 PF13428.1 OAJ17539.1 - 1.1e-05 25.6 10.0 9.1 7.2 0.0 7.9 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ17539.1 - 0.00071 19.1 0.0 2 8.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ17539.1 - 2.5 8.8 13.4 35 5.2 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Retrotrans_gag PF03732.12 OAJ17569.1 - 2.4e-08 33.9 0.1 1.9e-07 31.0 0.1 2.1 1 1 0 1 1 1 1 Retrotransposon gag protein rve PF00665.21 OAJ17570.1 - 3.8e-22 78.6 0.0 1.1e-21 77.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ17570.1 - 5.3e-22 78.2 0.1 3.5e-21 75.5 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CARD PF00619.16 OAJ17571.1 - 0.18 11.6 0.8 0.28 11.0 0.0 1.6 2 0 0 2 2 2 0 Caspase recruitment domain MFS_1 PF07690.11 OAJ17573.1 - 2.9e-36 124.9 23.0 1.3e-35 122.7 16.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 OAJ17574.1 - 1.2e-16 61.3 0.1 2.1e-16 60.4 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ17574.1 - 1.1e-15 57.6 0.0 2.1e-15 56.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ17574.1 - 4.7e-12 45.6 0.1 9.7e-12 44.5 0.1 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 OAJ17574.1 - 7.1e-06 25.7 1.1 0.0012 18.4 0.4 3.3 3 1 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 OAJ17574.1 - 1.6e-05 24.4 1.0 0.00099 18.6 0.0 2.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 OAJ17574.1 - 0.016 14.6 0.1 0.032 13.6 0.0 1.6 1 1 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.2 OAJ17575.1 - 1.9e-18 67.1 0.2 3.4e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ17575.1 - 3e-10 40.0 0.0 6.2e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ17575.1 - 5.5e-06 26.1 0.4 1e-05 25.2 0.3 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 OAJ17575.1 - 0.0001 21.9 0.1 0.00084 18.9 0.2 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold SH3_9 PF14604.1 OAJ17576.1 - 8.9e-06 25.2 0.0 2.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ17576.1 - 9.9e-05 21.7 0.0 0.00034 20.0 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 OAJ17576.1 - 0.00034 19.9 0.0 0.63 9.4 0.0 2.5 2 0 0 2 2 2 2 SH3 domain Ldh_1_N PF00056.18 OAJ17577.1 - 0.0019 18.0 0.1 0.0028 17.5 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain MFS_1 PF07690.11 OAJ17579.1 - 6.5e-42 143.5 26.2 6.5e-42 143.5 18.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Chitin_synth_2 PF03142.10 OAJ17579.1 - 0.043 12.1 0.2 0.07 11.5 0.1 1.2 1 0 0 1 1 1 0 Chitin synthase Rdx PF10262.4 OAJ17580.1 - 1.7e-20 72.7 0.0 3.8e-20 71.6 0.0 1.6 1 1 0 1 1 1 1 Rdx family ACPS PF01648.15 OAJ17613.1 - 3.5e-08 33.2 0.0 1e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF2419 PF10343.4 OAJ17618.1 - 1.1e-06 28.0 0.0 0.00024 20.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2419) START PF01852.14 OAJ17619.1 - 0.017 14.4 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 START domain Lin-8 PF03353.10 OAJ17619.1 - 1.1 8.4 4.9 2 7.6 3.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nif11 PF07862.6 OAJ17620.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function Serinc PF03348.10 OAJ17620.1 - 0.63 8.6 3.8 0.81 8.3 2.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) F-box-like PF12937.2 OAJ17621.1 - 0.00083 19.0 0.3 0.0019 17.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like Pyr_redox_2 PF07992.9 OAJ17622.1 - 6e-25 88.2 0.0 5e-09 36.3 0.0 4.1 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ17622.1 - 2e-13 50.5 0.0 3.9e-08 33.5 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAJ17622.1 - 8.2e-07 29.2 0.0 0.0017 18.4 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 OAJ17622.1 - 0.0066 16.6 0.0 0.35 11.1 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding TrkA_N PF02254.13 OAJ17622.1 - 0.0099 15.8 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_8 PF13450.1 OAJ17622.1 - 0.026 14.5 0.0 11 6.1 0.0 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain UQ_con PF00179.21 OAJ17622.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Ins_P5_2-kin PF06090.7 OAJ17649.1 - 4.2e-44 150.8 0.0 3.7e-43 147.7 0.0 2.0 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase zf-C2H2 PF00096.21 OAJ17649.1 - 3.6e-11 42.7 7.6 3.7e-05 23.7 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ17649.1 - 1.2e-05 25.3 6.6 0.038 14.3 1.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ17649.1 - 0.00055 20.0 9.3 0.00061 19.9 0.4 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 OAJ17649.1 - 0.096 12.6 1.4 7.5 6.6 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 OAJ17649.1 - 0.94 9.2 3.5 15 5.3 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 OAJ17649.1 - 0.98 9.6 10.0 0.6 10.3 1.2 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Glypican PF01153.14 OAJ17650.1 - 2 6.9 4.4 3.8 5.9 3.1 1.4 1 0 0 1 1 1 0 Glypican DUF3337 PF11816.3 OAJ17652.1 - 3.7e-41 141.6 0.0 8e-40 137.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 OAJ17652.1 - 1.1e-31 107.4 23.4 1e-09 37.8 0.1 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 OAJ17652.1 - 0.21 9.6 2.5 4 5.4 0.0 3.0 4 0 0 4 4 4 0 Nucleoporin Nup120/160 Pirin PF02678.11 OAJ17653.1 - 1.8e-28 98.5 1.3 2.8e-28 97.9 0.9 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 OAJ17653.1 - 1.4e-06 27.6 1.6 1.3e-05 24.5 0.3 2.4 2 0 0 2 2 2 1 Cupin domain CAML PF14963.1 OAJ17653.1 - 0.076 12.3 0.0 0.14 11.5 0.0 1.4 1 1 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Tubulin PF00091.20 OAJ17654.1 - 2.7e-72 243.1 0.0 4.7e-72 242.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 OAJ17654.1 - 4.3e-49 165.7 0.5 6.7e-49 165.1 0.3 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 OAJ17654.1 - 4.7e-07 29.8 0.1 1.3e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 OAJ17654.1 - 0.00063 19.2 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF1762 PF08574.5 OAJ17683.1 - 0.0022 18.3 9.7 0.0022 18.3 6.7 3.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1762) Thioesterase PF00975.15 OAJ17684.1 - 1.1e-09 38.8 0.4 2.5e-09 37.6 0.2 1.7 2 0 0 2 2 2 1 Thioesterase domain DUF2235 PF09994.4 OAJ17685.1 - 9.7e-63 212.1 0.0 2.3e-62 210.9 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 OAJ17685.1 - 0.021 14.6 0.0 0.079 12.7 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family TauD PF02668.11 OAJ17686.1 - 2.2e-25 89.7 0.0 2.8e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TFIIA PF03153.8 OAJ17687.1 - 0.0013 18.7 23.7 0.0013 18.7 16.4 3.6 2 2 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 OAJ17687.1 - 1.9 6.3 16.2 3.5 5.4 11.2 1.3 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 OAJ17687.1 - 7.6 6.0 10.9 9.3 5.8 5.8 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region TPR_2 PF07719.12 OAJ17689.1 - 0.016 15.0 2.1 1.3 9.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 OAJ17689.1 - 0.043 14.1 2.9 7.9 6.7 0.9 2.5 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_12 PF13424.1 OAJ17689.1 - 0.076 12.9 7.1 6.4 6.8 1.8 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C48 PF02902.14 OAJ17690.1 - 1e-07 31.8 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FAD_binding_4 PF01565.18 OAJ17691.1 - 3.2e-21 75.2 3.0 6.4e-21 74.2 2.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAJ17691.1 - 0.0062 16.4 0.1 0.017 15.0 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF3245 PF11595.3 OAJ17694.1 - 0.17 12.1 6.1 6.2 7.0 4.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3245) CENP-B_dimeris PF09026.5 OAJ17694.1 - 0.3 11.3 6.3 0.25 11.6 2.6 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 OAJ17694.1 - 9.7 6.5 9.7 21 5.5 6.4 1.8 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal OPT PF03169.10 OAJ17724.1 - 3.2e-145 485.0 44.1 4e-141 471.5 28.7 2.3 2 1 0 2 2 2 2 OPT oligopeptide transporter protein SUR7 PF06687.7 OAJ17725.1 - 5.7e-17 61.9 7.3 7.9e-17 61.5 5.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 OAJ17725.1 - 2.6e-08 33.7 2.2 2.6e-08 33.7 1.5 2.2 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF3754 PF12576.3 OAJ17725.1 - 1.2 8.8 4.7 2.3 7.8 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) UAA PF08449.6 OAJ17726.1 - 5.8e-66 222.4 4.2 7.5e-59 199.1 3.4 2.4 2 1 0 2 2 2 2 UAA transporter family EamA PF00892.15 OAJ17726.1 - 6.3e-06 26.2 2.5 6.3e-06 26.2 1.7 4.6 4 1 1 5 5 5 1 EamA-like transporter family TPT PF03151.11 OAJ17726.1 - 0.00024 20.7 14.0 0.0023 17.5 5.0 3.2 3 1 0 3 3 3 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 OAJ17726.1 - 0.00081 18.5 3.4 0.078 12.0 0.1 2.6 3 0 0 3 3 3 2 Nucleotide-sugar transporter CbiG_N PF11760.3 OAJ17726.1 - 0.11 12.2 2.1 0.21 11.2 0.1 2.4 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal UPF0546 PF10639.4 OAJ17726.1 - 0.23 11.2 6.7 1.5 8.6 0.2 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0546 EmrE PF13536.1 OAJ17726.1 - 0.83 9.8 24.1 0.021 15.0 3.6 3.7 3 1 0 3 3 3 0 Multidrug resistance efflux transporter EthD PF07110.6 OAJ17727.1 - 0.00023 22.0 0.8 0.051 14.4 0.1 2.8 2 1 0 2 2 2 2 EthD domain UDPGP PF01704.13 OAJ17728.1 - 3.5e-184 612.1 0.5 4.1e-184 611.9 0.3 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase tRNA-synt_2d PF01409.15 OAJ17729.1 - 2.3e-43 148.2 0.2 1.3e-25 90.0 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 OAJ17729.1 - 4.4e-23 81.2 0.0 1e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain GATase_7 PF13537.1 OAJ17730.1 - 4.3e-10 39.3 0.0 8e-10 38.5 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 OAJ17730.1 - 2.4e-08 34.0 0.0 3.1e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 OAJ17730.1 - 0.047 12.4 0.0 0.33 9.5 0.0 1.9 1 1 0 1 1 1 0 Glutamine amidotransferases class-II RBD PF02196.10 OAJ17730.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Raf-like Ras-binding domain Adap_comp_sub PF00928.16 OAJ17731.1 - 3.1e-90 301.8 0.0 4.1e-90 301.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 OAJ17731.1 - 6.7e-08 32.3 0.1 1.1e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF883 PF05957.8 OAJ17732.1 - 0.03 14.7 0.4 0.03 14.7 0.3 3.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Nop14 PF04147.7 OAJ17732.1 - 0.17 9.7 2.9 0.29 9.0 2.0 1.3 1 0 0 1 1 1 0 Nop14-like family RRM_1 PF00076.17 OAJ17733.1 - 1.2e-14 53.6 0.0 1.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ17733.1 - 4.4e-11 42.6 0.0 6.8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ17733.1 - 9.3e-08 31.8 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF566 PF04484.7 OAJ17733.1 - 9 5.7 8.4 14 5.0 5.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ribosomal_L18e PF00828.14 OAJ17734.1 - 4.3e-24 85.3 0.9 5.4e-24 85.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 DDE_3 PF13358.1 OAJ17735.1 - 9.9e-22 77.2 0.0 1.7e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 OAJ17735.1 - 7.9e-16 57.8 3.7 8.2e-16 57.8 1.4 2.0 2 0 0 2 2 2 1 Transposase rve PF00665.21 OAJ17735.1 - 0.00066 19.7 0.3 0.0019 18.2 0.0 1.9 2 1 1 3 3 3 1 Integrase core domain HTH_38 PF13936.1 OAJ17735.1 - 0.002 17.6 1.2 0.085 12.4 0.1 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.1 OAJ17735.1 - 0.0092 16.1 0.3 0.0092 16.1 0.2 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_31 PF13560.1 OAJ17735.1 - 0.029 14.5 3.0 0.99 9.6 0.3 3.1 3 1 0 3 3 3 0 Helix-turn-helix domain HTH_32 PF13565.1 OAJ17735.1 - 1.5 9.6 13.9 0.5 11.1 0.4 4.1 3 1 0 4 4 4 0 Homeodomain-like domain MBOAT PF03062.14 OAJ17761.1 - 6.3e-06 25.5 8.3 0.019 14.1 2.4 2.3 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 OAJ17761.1 - 9.7e-06 25.5 1.8 0.0043 17.1 0.2 2.6 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family RRM_6 PF14259.1 OAJ17764.1 - 4.2e-06 26.6 0.0 7.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ17764.1 - 7.2e-06 25.5 0.0 4.8e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ17764.1 - 1e-05 25.2 0.0 2.3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 OAJ17764.1 - 0.005 16.5 0.0 0.0098 15.6 0.0 1.5 1 0 0 1 1 1 1 Limkain b1 zf-CCCH_2 PF14608.1 OAJ17764.1 - 0.0061 16.5 2.4 0.019 14.9 1.7 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type FYVE PF01363.16 OAJ17764.1 - 0.007 16.2 0.2 0.007 16.2 0.2 2.1 3 0 0 3 3 3 1 FYVE zinc finger zf-CCCH PF00642.19 OAJ17764.1 - 0.018 14.6 1.2 0.018 14.6 0.8 2.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MA3 PF02847.12 OAJ17765.1 - 5.8e-27 93.6 1.8 4.5e-26 90.7 0.1 2.4 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 OAJ17765.1 - 2.4e-24 85.9 0.2 1.4e-23 83.4 0.0 2.3 2 1 0 2 2 2 1 MIF4G domain RXT2_N PF08595.6 OAJ17765.1 - 2.3e-05 24.2 14.2 0.21 11.3 0.0 4.7 4 0 0 4 4 4 2 RXT2-like, N-terminal MFS_1 PF07690.11 OAJ17766.1 - 1.3e-07 30.6 23.2 1.3e-07 30.6 16.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro_CA PF00484.14 OAJ17795.1 - 3.3e-37 127.8 0.0 4.3e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_1 PF00561.15 OAJ17795.1 - 0.034 13.6 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2236 PF09995.4 OAJ17796.1 - 1.4e-20 73.6 1.5 3.5e-19 69.0 1.0 2.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Maf PF02545.9 OAJ17797.1 - 1.1e-44 151.9 0.0 1.3e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein GATA PF00320.22 OAJ17799.1 - 0.0022 17.2 10.2 0.004 16.4 2.4 3.4 3 0 0 3 3 3 2 GATA zinc finger ADH_zinc_N PF00107.21 OAJ17801.1 - 1.8e-11 43.7 0.0 3.3e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ17801.1 - 0.0019 17.9 0.0 0.033 13.9 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Metallophos PF00149.23 OAJ17802.1 - 2.7e-07 30.1 0.1 5.7e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Lipase_GDSL_3 PF14606.1 OAJ17802.1 - 0.057 13.1 0.1 7 6.3 0.0 2.3 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family ABC_tran PF00005.22 OAJ17803.1 - 5.2e-47 159.5 0.0 4.5e-27 95.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 OAJ17803.1 - 5.5e-38 130.9 17.9 5.9e-17 61.9 7.4 3.7 3 1 0 3 3 3 3 ABC transporter transmembrane region AAA_23 PF13476.1 OAJ17803.1 - 6.7e-12 46.1 0.6 4.3e-06 27.1 0.4 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 OAJ17803.1 - 2.4e-10 40.8 0.5 0.001 19.1 0.0 4.2 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 OAJ17803.1 - 8e-09 35.0 6.3 0.0028 16.9 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 OAJ17803.1 - 1.3e-08 34.2 0.7 0.0025 17.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 OAJ17803.1 - 4.6e-07 29.0 0.2 0.0016 17.3 0.0 2.7 3 0 0 3 3 2 2 Type II/IV secretion system protein DUF258 PF03193.11 OAJ17803.1 - 1.1e-06 27.9 0.1 0.02 14.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 OAJ17803.1 - 1.8e-06 28.4 0.8 0.032 14.7 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 OAJ17803.1 - 4e-06 26.9 1.1 0.037 14.0 0.1 3.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 OAJ17803.1 - 5.6e-05 22.6 0.0 0.1 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 OAJ17803.1 - 5.8e-05 23.0 1.2 0.031 14.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.1 OAJ17803.1 - 6.5e-05 22.1 0.1 0.033 13.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.18 OAJ17803.1 - 7.1e-05 22.6 3.0 0.13 12.0 0.3 2.6 2 0 0 2 2 2 2 Dynamin family AAA_30 PF13604.1 OAJ17803.1 - 0.0002 20.9 0.7 0.81 9.2 0.2 3.4 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 OAJ17803.1 - 0.00024 20.9 2.4 0.0015 18.3 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 Adeno_IVa2 PF02456.10 OAJ17803.1 - 0.00026 19.7 0.0 0.097 11.2 0.0 2.2 2 0 0 2 2 2 2 Adenovirus IVa2 protein FtsK_SpoIIIE PF01580.13 OAJ17803.1 - 0.0004 19.9 0.3 0.24 10.8 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 OAJ17803.1 - 0.0005 19.2 0.1 0.15 11.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 OAJ17803.1 - 0.00051 19.9 0.4 1.9 8.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 OAJ17803.1 - 0.00087 18.8 1.0 0.21 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain MobB PF03205.9 OAJ17803.1 - 0.0012 18.5 1.0 0.13 11.9 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 OAJ17803.1 - 0.0014 18.7 0.4 3.7 7.7 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_17 PF13207.1 OAJ17803.1 - 0.0055 17.5 1.9 0.64 10.8 0.1 3.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 OAJ17803.1 - 0.018 14.7 0.8 5.9 6.5 0.1 2.7 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.4 OAJ17803.1 - 0.021 13.4 0.1 0.62 8.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain GTP_EFTU PF00009.22 OAJ17803.1 - 0.03 13.7 0.0 5.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_ATPase PF09818.4 OAJ17803.1 - 0.04 12.4 5.0 2.1 6.8 0.0 3.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA PF00004.24 OAJ17803.1 - 0.05 13.8 0.1 19 5.4 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 OAJ17803.1 - 0.077 11.9 0.0 9.7 5.1 0.0 2.2 2 0 0 2 2 2 0 Septin DUF815 PF05673.8 OAJ17803.1 - 0.083 11.7 0.2 2.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 OAJ17803.1 - 0.11 11.9 0.1 13 5.1 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 OAJ17803.1 - 0.12 12.5 0.3 27 5.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 OAJ17803.1 - 0.13 12.2 0.0 30 4.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 OAJ17803.1 - 0.15 11.5 3.6 4 6.8 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 OAJ17803.1 - 0.23 11.1 0.6 12 5.5 0.0 2.5 2 0 0 2 2 2 0 NTPase Pox_A32 PF04665.7 OAJ17803.1 - 0.43 9.8 0.1 2.8 7.1 0.0 2.0 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_18 PF13238.1 OAJ17803.1 - 0.68 10.2 4.9 2 8.7 0.2 3.2 3 0 0 3 3 3 0 AAA domain UDPGT PF00201.13 OAJ17804.1 - 6.1e-15 54.7 0.1 9.3e-15 54.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GHMP_kinases_C PF08544.8 OAJ17804.1 - 0.015 15.4 0.1 0.65 10.2 0.0 2.5 1 1 0 1 1 1 0 GHMP kinases C terminal Glyco_trans_1_3 PF13528.1 OAJ17804.1 - 0.18 10.9 0.0 0.39 9.8 0.0 1.4 2 0 0 2 2 2 0 Glycosyl transferase family 1 UDPGT PF00201.13 OAJ17805.1 - 2.2e-13 49.6 0.1 3.7e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.13 OAJ17806.1 - 5.9e-14 51.4 0.4 1.2e-13 50.5 0.2 1.3 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 OAJ17806.1 - 0.082 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 Ank_4 PF13637.1 OAJ17829.1 - 1e-12 48.1 0.8 1.1e-06 28.9 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 OAJ17829.1 - 1.5e-10 41.2 0.0 2.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ17829.1 - 3.3e-07 29.7 0.4 3.4e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 OAJ17829.1 - 3.4e-06 26.7 0.4 0.00049 20.0 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 OAJ17829.1 - 5.8e-06 26.3 0.7 3.4e-05 23.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Methyltransf_18 PF12847.2 OAJ17829.1 - 0.00046 20.7 0.0 0.0024 18.4 0.0 2.1 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ17829.1 - 0.0019 18.6 0.0 0.0042 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 OAJ17829.1 - 0.0038 18.0 0.1 0.014 16.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain TB2_DP1_HVA22 PF03134.14 OAJ17831.1 - 1.5e-05 24.6 0.2 3.1e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Myb_DNA-binding PF00249.26 OAJ17834.1 - 6.7e-11 42.0 0.9 1.4e-10 41.0 0.6 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ17834.1 - 6.4e-07 29.3 1.9 1.3e-06 28.4 0.6 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Pox_A_type_inc PF04508.7 OAJ17835.1 - 0.022 14.5 1.2 2 8.4 0.0 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat FAD-oxidase_C PF02913.14 OAJ17835.1 - 0.058 12.6 0.5 0.088 12.1 0.3 1.4 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Lebercilin PF15619.1 OAJ17835.1 - 0.54 9.6 6.7 0.38 10.1 2.4 2.3 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease AAA PF00004.24 OAJ17837.1 - 4.7e-52 175.6 0.0 7.3e-39 132.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.12 OAJ17837.1 - 1.3e-09 37.5 0.1 2e-08 33.7 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.9 OAJ17837.1 - 2.7e-08 33.9 0.1 1.8e-05 24.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 OAJ17837.1 - 4e-07 30.8 0.1 0.0068 17.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAJ17837.1 - 7.6e-07 29.3 0.1 0.0012 19.0 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 OAJ17837.1 - 8.6e-07 28.9 0.0 0.012 15.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 OAJ17837.1 - 1e-06 27.9 0.3 0.024 13.7 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 OAJ17837.1 - 1.4e-06 27.3 0.1 0.042 12.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 OAJ17837.1 - 3.3e-06 27.0 0.0 0.062 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 OAJ17837.1 - 4e-06 27.1 0.1 0.0074 16.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 OAJ17837.1 - 4.7e-06 26.3 0.0 0.002 17.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 OAJ17837.1 - 7.6e-06 25.2 0.4 0.006 15.7 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 OAJ17837.1 - 1.2e-05 24.9 1.4 0.12 12.1 0.0 3.2 2 0 0 2 2 2 2 Part of AAA domain AAA_16 PF13191.1 OAJ17837.1 - 1.6e-05 25.0 0.1 0.12 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.12 OAJ17837.1 - 0.00014 21.3 0.5 0.031 13.7 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 OAJ17837.1 - 0.00015 21.8 0.0 0.097 12.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Parvo_NS1 PF01057.12 OAJ17837.1 - 0.00025 20.0 0.0 0.16 10.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 KTI12 PF08433.5 OAJ17837.1 - 0.00027 20.2 0.1 0.17 11.0 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_28 PF13521.1 OAJ17837.1 - 0.00028 20.8 0.0 0.79 9.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAJ17837.1 - 0.00034 20.0 0.5 0.58 9.5 0.0 3.2 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.7 OAJ17837.1 - 0.00038 19.6 0.1 0.66 9.0 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin CDC48_N PF02359.13 OAJ17837.1 - 0.00078 19.3 0.0 0.003 17.4 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain ABC_tran PF00005.22 OAJ17837.1 - 0.0012 19.1 0.4 0.037 14.3 0.0 2.6 2 0 0 2 2 2 1 ABC transporter KaiC PF06745.8 OAJ17837.1 - 0.0015 17.6 0.6 0.011 14.8 0.1 2.2 2 0 0 2 2 2 1 KaiC Sigma54_activat PF00158.21 OAJ17837.1 - 0.0022 17.4 0.0 0.82 9.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 OAJ17837.1 - 0.0032 17.0 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 OAJ17837.1 - 0.004 16.7 0.2 0.32 10.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 OAJ17837.1 - 0.0046 16.6 0.1 0.045 13.3 0.0 2.2 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.1 OAJ17837.1 - 0.0057 16.2 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 OAJ17837.1 - 0.006 16.2 0.1 0.54 9.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 OAJ17837.1 - 0.0066 16.1 1.1 3.6 7.2 0.0 3.3 4 0 0 4 4 3 1 NACHT domain PhoH PF02562.11 OAJ17837.1 - 0.01 15.0 0.0 0.82 8.8 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein Arch_ATPase PF01637.13 OAJ17837.1 - 0.016 14.8 0.5 35 3.9 0.0 3.5 2 2 1 4 4 4 0 Archaeal ATPase AAA_30 PF13604.1 OAJ17837.1 - 0.023 14.2 0.1 0.89 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 OAJ17837.1 - 0.034 13.0 0.0 2.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 OAJ17837.1 - 0.065 13.2 0.0 12 5.9 0.0 3.3 3 1 0 3 3 2 0 Sigma-54 interaction domain IPT PF01745.11 OAJ17837.1 - 0.081 12.0 0.4 1.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Isopentenyl transferase DUF2075 PF09848.4 OAJ17837.1 - 0.12 11.3 0.0 0.73 8.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Fungal_trans PF04082.13 OAJ17865.1 - 9e-10 37.8 0.1 2.4e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ17865.1 - 8.9e-08 31.9 6.2 1.5e-07 31.2 4.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polysacc_deac_1 PF01522.16 OAJ17866.1 - 3.9e-12 45.8 0.0 7.5e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Herpes_capsid PF06112.6 OAJ17867.1 - 0.15 12.0 5.7 0.18 11.8 4.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Brr6_like_C_C PF10104.4 OAJ17869.1 - 0.033 13.6 0.8 0.033 13.6 0.6 1.6 1 1 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain PetN PF03742.9 OAJ17869.1 - 0.1 12.1 0.2 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 PetN Fungal_trans PF04082.13 OAJ17870.1 - 1.9e-09 36.7 0.0 4e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ17870.1 - 2.1e-07 30.7 8.2 3.8e-07 29.8 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 OAJ17870.1 - 0.057 13.6 9.0 0.11 12.6 6.2 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Peptidase_M16_C PF05193.16 OAJ17870.1 - 0.2 11.3 0.0 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase M16 inactive domain Sec20 PF03908.8 OAJ17871.1 - 3.9e-20 71.3 0.7 3.9e-20 71.3 0.5 1.9 2 0 0 2 2 2 1 Sec20 EHN PF06441.7 OAJ17872.1 - 2.2e-26 91.9 0.0 3.9e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 OAJ17872.1 - 6.5e-07 29.4 4.2 8.5e-07 29.0 1.4 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ17872.1 - 0.00035 20.1 0.1 0.0011 18.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DNA_ligase_A_N PF04675.9 OAJ17873.1 - 2.9e-10 40.2 0.0 3.9e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 DNA ligase N terminus DUF4149 PF13664.1 OAJ17898.1 - 4.6e-19 68.3 3.4 4.6e-19 68.3 2.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF2945 PF11160.3 OAJ17899.1 - 1.8e-11 43.6 1.9 7e-11 41.7 0.0 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2945) MIP-T3 PF10243.4 OAJ17899.1 - 0.013 13.9 65.2 0.017 13.6 45.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 OAJ17899.1 - 7.6 4.6 36.9 9.3 4.3 25.6 1.2 1 0 0 1 1 1 0 Transmembrane protein CAP_GLY PF01302.20 OAJ17900.1 - 1.3e-19 69.6 0.1 2.6e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 OAJ17900.1 - 8.3e-09 34.8 7.6 5e-05 22.8 0.7 5.4 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ17900.1 - 7.8e-06 25.5 1.5 0.058 13.1 0.1 4.1 3 1 2 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 OAJ17900.1 - 0.82 9.9 2.6 22 5.4 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.28 OAJ17900.1 - 3 8.2 11.7 65 4.1 0.1 5.2 4 2 1 5 5 5 0 Leucine Rich Repeat FRG1 PF06229.7 OAJ17901.1 - 7.7e-21 74.4 3.3 1.2e-08 34.6 0.0 3.4 3 0 0 3 3 3 3 FRG1-like family Fascin PF06268.8 OAJ17901.1 - 1.3e-06 28.5 0.0 0.001 19.1 0.0 2.5 2 0 0 2 2 2 2 Fascin domain DUF4444 PF14563.1 OAJ17901.1 - 0.055 12.8 0.1 13 5.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4444) SNARE_assoc PF09335.6 OAJ17902.1 - 6.6e-15 55.4 1.3 1.5e-14 54.2 0.9 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein PUF PF00806.14 OAJ17903.1 - 1e-14 53.0 0.9 2.3e-07 29.8 0.0 4.8 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat Abhydrolase_5 PF12695.2 OAJ17904.1 - 8.5e-05 22.3 0.0 0.00021 21.0 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 OAJ17904.1 - 0.00015 21.0 0.0 0.00029 20.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 OAJ17904.1 - 0.0014 18.5 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAJ17904.1 - 0.0087 15.6 0.0 0.029 13.9 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein DNase_NucA_NucB PF14040.1 OAJ17906.1 - 4.4e-26 91.2 1.5 6.3e-26 90.7 1.0 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Me-amine-dh_L PF02975.9 OAJ17906.1 - 1.8 8.5 8.8 0.28 11.1 3.3 1.7 1 1 0 1 1 1 0 Methylamine dehydrogenase, L chain FGGY_N PF00370.16 OAJ17907.1 - 2.1e-72 243.3 0.1 3e-72 242.8 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 OAJ17907.1 - 1e-67 227.5 3.1 2.5e-67 226.3 1.2 2.1 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Polyketide_cyc PF03364.15 OAJ17935.1 - 1.9e-22 79.6 0.1 4.4e-22 78.4 0.1 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 OAJ17935.1 - 0.0021 18.2 0.2 0.021 15.0 0.1 2.2 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Pheromone PF08015.6 OAJ17935.1 - 1.5 9.7 10.9 0.27 12.0 4.3 2.3 2 0 0 2 2 2 0 Fungal mating-type pheromone BTB PF00651.26 OAJ17936.1 - 1.4e-05 25.0 0.0 0.013 15.5 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ribosomal_L32p PF01783.18 OAJ17937.1 - 1.8e-13 50.4 6.6 4.1e-13 49.3 4.6 1.6 1 0 0 1 1 1 1 Ribosomal L32p protein family DUF164 PF02591.10 OAJ17937.1 - 0.14 12.0 2.6 2.3 8.1 0.2 2.4 1 1 1 2 2 2 0 Putative zinc ribbon domain SynMuv_product PF06047.6 OAJ17938.1 - 2.1e-47 159.1 3.5 6.3e-47 157.6 2.5 1.8 1 0 0 1 1 1 1 Ras-induced vulval development antagonist ABC_ATPase PF09818.4 OAJ17939.1 - 4.3e-08 32.1 0.0 6.7e-08 31.5 0.0 1.3 1 1 0 1 1 1 1 Predicted ATPase of the ABC class FGase PF05013.7 OAJ17939.1 - 0.028 14.2 0.0 1 9.2 0.0 2.1 1 1 1 2 2 2 0 N-formylglutamate amidohydrolase EF-hand_7 PF13499.1 OAJ17940.1 - 5e-06 26.5 0.2 5e-06 26.5 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 OAJ17940.1 - 8.5e-06 25.2 0.2 0.072 13.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 OAJ17940.1 - 1.3e-05 24.2 0.1 0.088 12.1 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.27 OAJ17940.1 - 2.7e-05 23.1 0.2 0.14 11.5 0.0 2.8 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.4 OAJ17940.1 - 0.2 11.6 3.7 1.5 8.8 0.0 3.6 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region WD40 PF00400.27 OAJ17941.1 - 6.8e-48 158.9 15.7 3.2e-09 36.3 0.0 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat PQQ_3 PF13570.1 OAJ17941.1 - 0.031 14.5 0.8 30 5.0 0.0 3.8 3 0 0 3 3 3 0 PQQ-like domain Nup160 PF11715.3 OAJ17941.1 - 0.046 11.8 2.1 0.29 9.2 0.1 2.7 1 1 1 3 3 3 0 Nucleoporin Nup120/160 CLTH PF10607.4 OAJ17941.1 - 0.047 13.3 0.1 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Caudo_TAP PF02413.12 OAJ17941.1 - 2.5 8.2 8.2 0.29 11.2 0.3 2.8 3 0 0 3 3 3 0 Caudovirales tail fibre assembly protein FtsJ PF01728.14 OAJ17942.1 - 4.9e-56 189.5 0.0 6.4e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 OAJ17942.1 - 0.00012 22.6 0.0 0.002 18.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ17942.1 - 0.00063 19.3 0.0 0.0034 16.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ17942.1 - 0.0016 18.7 0.0 0.0064 16.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ17942.1 - 0.016 14.9 0.0 0.051 13.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain CbiA PF01656.18 OAJ17942.1 - 0.047 13.0 0.3 0.15 11.4 0.1 1.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ubie_methyltran PF01209.13 OAJ17942.1 - 0.14 11.2 0.0 0.46 9.5 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Mur_ligase_M PF08245.7 OAJ17943.1 - 4e-05 23.7 0.0 0.16 11.9 0.0 2.8 2 1 0 2 2 2 2 Mur ligase middle domain AAR2 PF05282.6 OAJ17944.1 - 2.3e-35 122.2 0.0 1.3e-34 119.7 0.0 2.1 1 1 1 2 2 2 1 AAR2 protein DUF4414 PF14377.1 OAJ17944.1 - 2 8.3 9.9 0.62 10.0 0.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4414) zf-RING_2 PF13639.1 OAJ17945.1 - 7e-08 32.1 7.1 1.4e-07 31.2 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAJ17945.1 - 2.7e-06 27.3 1.0 6.6e-06 26.1 0.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 OAJ17945.1 - 0.0011 18.7 1.5 0.0026 17.5 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 OAJ17945.1 - 0.0048 16.8 3.7 0.011 15.6 2.5 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 OAJ17945.1 - 0.0074 16.3 6.1 0.017 15.1 4.3 1.7 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.20 OAJ17945.1 - 0.011 15.3 8.4 0.02 14.5 5.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 OAJ17945.1 - 0.28 10.9 3.5 0.56 9.9 2.4 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 OAJ17945.1 - 0.53 10.3 8.9 1.1 9.3 6.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 OAJ17945.1 - 2.6 7.8 5.2 4.7 6.9 3.6 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.1 OAJ17945.1 - 4.7 6.9 5.2 8.6 6.1 3.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ17945.1 - 6.1 6.6 6.5 10 5.9 4.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Ndc1_Nup PF09531.5 OAJ17946.1 - 5.5 5.2 8.5 7.9 4.7 5.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cullin PF00888.17 OAJ17947.1 - 2.5e-104 349.9 0.0 5.9e-104 348.7 0.0 1.5 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 OAJ17947.1 - 2.1e-20 72.3 0.7 5.7e-20 70.9 0.5 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF2407 PF10302.4 OAJ17947.1 - 0.096 12.8 0.3 0.36 11.0 0.2 2.0 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain SEP PF08059.8 OAJ17971.1 - 8e-19 67.7 0.0 1.5e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 OAJ17971.1 - 3.4e-13 49.4 0.0 5.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 OAJ17971.1 - 2.1e-09 36.7 1.5 3.6e-09 36.0 1.1 1.4 1 0 0 1 1 1 1 UBA-like domain ACC_central PF08326.7 OAJ17972.1 - 2.5e-186 620.9 0.0 3.8e-186 620.3 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 OAJ17972.1 - 2.6e-160 534.0 0.0 3.5e-160 533.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 OAJ17972.1 - 1.4e-52 178.0 0.0 3e-52 176.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 OAJ17972.1 - 2.3e-24 85.6 0.1 5.5e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 OAJ17972.1 - 1.1e-21 76.8 0.0 3e-20 72.1 0.0 3.0 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 OAJ17972.1 - 1.3e-14 53.5 0.2 2.5e-14 52.6 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 OAJ17972.1 - 2e-12 47.2 0.0 7.5e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 OAJ17972.1 - 3.9e-06 26.4 0.0 1.3e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp PF02222.17 OAJ17972.1 - 0.00082 18.7 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.1 OAJ17972.1 - 0.0027 17.3 0.0 0.0078 15.9 0.0 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain ATP-grasp_3 PF02655.9 OAJ17972.1 - 0.013 15.4 0.0 0.046 13.5 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain Dala_Dala_lig_C PF07478.8 OAJ17972.1 - 0.025 13.9 0.0 0.061 12.7 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus RimK PF08443.6 OAJ17972.1 - 0.08 12.4 0.0 1.5 8.2 0.0 2.6 2 1 0 2 2 2 0 RimK-like ATP-grasp domain HlyD_2 PF12700.2 OAJ17972.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Ubiq_cyt_C_chap PF03981.7 OAJ17973.1 - 2.2e-29 102.0 0.1 1.2e-25 90.0 0.0 2.3 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone Gpi16 PF04113.9 OAJ17975.1 - 2.7e-91 306.2 0.0 3.2e-41 141.0 0.0 4.3 3 1 0 3 3 3 3 Gpi16 subunit, GPI transamidase component DUF3283 PF11686.3 OAJ17975.1 - 0.21 11.3 0.0 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) Aminotran_1_2 PF00155.16 OAJ17976.1 - 2.8e-43 148.2 0.0 1.2e-42 146.1 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Herpes_capsid PF06112.6 OAJ17976.1 - 0.75 9.8 4.0 1.4 8.9 2.8 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein zf-CCHC PF00098.18 OAJ17977.1 - 1.2e-05 24.9 3.8 2.2e-05 24.1 2.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Dimer_Tnp_hAT PF05699.9 OAJ17978.1 - 1e-08 34.6 0.0 2.8e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAJ17978.1 - 0.023 14.6 0.0 0.059 13.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) LAG1-DNAbind PF09271.6 OAJ18007.1 - 1.8e-22 80.3 1.9 5.9e-22 78.6 0.0 2.4 2 0 0 2 2 2 1 LAG1, DNA binding BTD PF09270.5 OAJ18007.1 - 6.3e-08 32.5 0.0 1.8e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain UvrD_C PF13361.1 OAJ18008.1 - 1.8e-70 238.1 0.0 6.2e-42 144.3 0.0 2.6 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 OAJ18008.1 - 2.8e-68 230.5 0.3 5.7e-68 229.5 0.2 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 OAJ18008.1 - 2.3e-11 43.7 0.0 6.9e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 OAJ18008.1 - 3.6e-11 42.6 0.1 1.4e-10 40.7 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 OAJ18008.1 - 1e-05 25.1 0.1 0.18 11.2 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 OAJ18008.1 - 0.0019 17.4 0.2 0.86 8.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein SMC_Nse1 PF07574.8 OAJ18008.1 - 0.029 13.9 0.3 0.072 12.7 0.2 1.6 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex WLM PF08325.5 OAJ18009.1 - 1.1e-42 146.0 0.3 4.7e-42 143.9 0.0 1.9 2 0 0 2 2 2 1 WLM domain zf-RanBP PF00641.13 OAJ18009.1 - 4.1e-06 25.7 3.2 6.7e-06 25.1 2.2 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others PhdYeFM_antitox PF02604.14 OAJ18009.1 - 0.041 13.4 0.3 0.11 12.1 0.2 1.7 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system DUF45 PF01863.12 OAJ18009.1 - 0.061 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 4HBT PF03061.17 OAJ18011.1 - 2.8e-09 36.9 0.0 5.1e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 OAJ18011.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4442) Herpes_UL33 PF03581.8 OAJ18011.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL33-like protein Ald_Xan_dh_C2 PF02738.13 OAJ18013.1 - 2.1e-175 584.1 0.0 2.8e-175 583.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.17 OAJ18013.1 - 1.4e-30 105.6 0.0 3.2e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.16 OAJ18013.1 - 9.5e-28 96.7 0.0 1.7e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.15 OAJ18013.1 - 2.6e-24 84.8 0.1 5.5e-24 83.8 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.12 OAJ18013.1 - 3.1e-20 72.0 1.3 2e-19 69.4 0.0 3.0 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.22 OAJ18013.1 - 1.9e-06 27.5 0.1 2.2e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Hamartin PF04388.7 OAJ18013.1 - 0.59 8.7 1.2 0.87 8.1 0.9 1.1 1 0 0 1 1 1 0 Hamartin protein CRAL_TRIO PF00650.15 OAJ18050.1 - 1.4e-11 44.1 0.0 7.5e-11 41.7 0.0 2.0 1 1 0 1 1 1 1 CRAL/TRIO domain Bunya_NS-S PF01104.12 OAJ18050.1 - 0.15 11.5 1.1 0.31 10.5 0.7 1.4 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s Peptidase_M43 PF05572.8 OAJ18051.1 - 3.6e-11 42.9 0.1 8.4e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Pkinase PF00069.20 OAJ18053.1 - 1.1e-05 24.7 0.0 3.2e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ18053.1 - 0.024 13.7 0.0 4.7 6.2 0.0 2.4 2 1 0 2 2 2 0 Protein tyrosine kinase Oxidored_FMN PF00724.15 OAJ18055.1 - 8e-62 209.1 0.0 2.1e-56 191.3 0.0 2.1 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_U32 PF01136.14 OAJ18055.1 - 0.16 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family U32 Redoxin PF08534.5 OAJ18056.1 - 1.2e-33 115.7 0.0 1.3e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAJ18056.1 - 2.8e-10 39.9 0.0 3.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Cellulase PF00150.13 OAJ18057.1 - 7.8e-12 44.9 5.9 1.1e-11 44.4 4.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) rve PF00665.21 OAJ18058.1 - 7.2e-05 22.8 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_Crp_2 PF13545.1 OAJ18058.1 - 0.027 14.2 0.4 0.086 12.6 0.1 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Trp_repressor PF01371.14 OAJ18058.1 - 0.051 13.4 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 Trp repressor protein DUF3376 PF11856.3 OAJ18059.1 - 0.0085 15.5 1.0 0.0099 15.2 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3376) Nop14 PF04147.7 OAJ18059.1 - 3 5.6 12.4 2.2 6.0 7.0 1.6 1 1 0 2 2 2 0 Nop14-like family U79_P34 PF03064.11 OAJ18059.1 - 3.4 7.1 7.3 4.7 6.6 5.1 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pkinase PF00069.20 OAJ18060.1 - 3.8e-11 42.6 0.0 7.3e-11 41.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ18060.1 - 1.2e-05 24.5 0.0 0.055 12.5 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Chitin_synth_2 PF03142.10 OAJ18089.1 - 3e-281 933.4 0.0 3.6e-281 933.1 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 OAJ18089.1 - 8.6e-17 61.4 0.7 2e-16 60.2 0.5 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ18089.1 - 3.2e-16 59.8 0.0 3.8e-15 56.3 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 OAJ18089.1 - 3.5e-05 23.1 0.1 0.00083 18.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 OAJ18089.1 - 0.0052 16.4 0.0 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Retrotrans_gag PF03732.12 OAJ18092.1 - 0.03 14.3 0.0 0.087 12.9 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.22 OAJ18093.1 - 3.5e-17 62.4 0.0 6.3e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ18093.1 - 2.2e-15 56.8 0.0 3.8e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ18093.1 - 0.00072 20.0 0.2 0.0019 18.6 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease rve PF00665.21 OAJ18096.1 - 2.4e-16 59.9 0.0 3.3e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 OAJ18098.1 - 1.5e-18 66.9 0.0 1.7e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 OAJ18098.1 - 7.1e-05 22.9 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain 2OG-Fe_Oxy_2 PF10014.4 OAJ18098.1 - 0.03 13.7 0.3 1.7 8.0 0.0 2.0 1 1 1 2 2 2 0 2OG-Fe dioxygenase DDE_Tnp_ISAZ013 PF07592.6 OAJ18098.1 - 0.032 12.9 0.0 0.033 12.9 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain RVT_2 PF07727.9 OAJ18126.1 - 2.3e-81 272.3 0.0 3.4e-81 271.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ18126.1 - 7.7e-20 71.1 0.0 5.6e-19 68.4 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 OAJ18126.1 - 2.9e-12 46.1 0.0 5.3e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAJ18126.1 - 3.5e-10 39.3 0.1 9.8e-10 37.9 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 OAJ18126.1 - 9.5e-08 31.8 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ18126.1 - 1.4e-06 27.9 2.5 3e-06 26.8 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle UBN2_3 PF14244.1 OAJ18126.1 - 0.056 13.0 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type rve_3 PF13683.1 OAJ18126.1 - 0.057 12.9 0.0 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain zf-CCHC_4 PF14392.1 OAJ18126.1 - 1.9 8.2 6.3 0.27 10.9 1.3 1.9 2 0 0 2 2 2 0 Zinc knuckle Carboxyl_trans PF01039.17 OAJ18127.1 - 0.0043 15.4 0.0 0.0053 15.1 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Cutinase PF01083.17 OAJ18128.1 - 1.5e-29 102.9 0.5 1.8e-29 102.7 0.3 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ18128.1 - 0.00065 19.3 0.0 0.00079 19.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ18128.1 - 0.0078 15.9 0.1 0.0096 15.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ18128.1 - 0.028 14.2 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 OAJ18128.1 - 0.033 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain RLAN PF14401.1 OAJ18131.1 - 0.00088 18.8 0.1 0.0013 18.2 0.1 1.4 1 0 0 1 1 1 1 RimK-like ATPgrasp N-terminal domain DUF4566 PF15130.1 OAJ18131.1 - 0.014 14.5 0.2 0.023 13.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4566) Retrotrans_gag PF03732.12 OAJ18133.1 - 0.0024 17.8 0.2 0.0043 17.0 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.22 OAJ18135.1 - 1.9e-19 69.8 0.0 3.5e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ18135.1 - 7.7e-16 58.2 0.0 1.9e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ18135.1 - 0.0009 19.7 0.0 0.0027 18.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 OAJ18135.1 - 0.0032 17.5 0.2 0.0069 16.4 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 OAJ18135.1 - 0.0048 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ18135.1 - 0.011 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease dUTPase PF00692.14 OAJ18135.1 - 0.044 13.2 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 dUTPase RVT_1 PF00078.22 OAJ18136.1 - 1.6e-18 66.8 0.0 2.7e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ18136.1 - 2.3e-14 53.5 0.0 7.1e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain DUF2360 PF10152.4 OAJ18136.1 - 0.00036 20.8 0.2 0.00036 20.8 0.1 2.7 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein (DUF2360) Asp_protease_2 PF13650.1 OAJ18136.1 - 0.0015 18.9 0.0 0.0036 17.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ18136.1 - 0.069 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease dUTPase PF00692.14 OAJ18136.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 dUTPase FHA PF00498.21 OAJ18167.1 - 0.00046 20.2 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 FHA domain Spt5-NGN PF03439.8 OAJ18168.1 - 2.9e-20 71.7 0.1 8.1e-20 70.3 0.0 1.8 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 OAJ18168.1 - 2.7e-11 43.9 10.3 2.7e-11 43.9 7.2 3.8 3 1 1 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 OAJ18168.1 - 3.5e-08 32.8 19.3 0.018 14.7 0.3 5.3 5 0 0 5 5 5 4 KOW motif DUF4537 PF15057.1 OAJ18168.1 - 0.006 16.3 0.7 15 5.3 0.2 3.9 2 1 2 4 4 4 1 Domain of unknown function (DUF4537) OPT PF03169.10 OAJ18170.1 - 5.7e-153 510.6 34.6 6.5e-153 510.4 24.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CENP-T PF15511.1 OAJ18170.1 - 0.053 12.7 4.3 0.076 12.2 3.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BofA PF07441.6 OAJ18170.1 - 0.12 12.3 7.1 0.028 14.4 1.8 2.3 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA HMG_box PF00505.14 OAJ18171.1 - 6.7e-08 32.6 0.6 1.4e-07 31.6 0.7 4.7 3 1 2 5 5 5 2 HMG (high mobility group) box DUF2461 PF09365.5 OAJ18172.1 - 1.2e-55 188.1 0.0 1.7e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Pkinase PF00069.20 OAJ18173.1 - 1e-59 201.7 0.0 2.2e-34 118.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ18173.1 - 8.4e-23 80.7 0.0 2.1e-20 72.9 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Metallophos PF00149.23 OAJ18174.1 - 6.3e-41 139.9 0.9 9.6e-41 139.3 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Autophagy_Cterm PF10381.4 OAJ18174.1 - 0.88 8.7 3.3 0.71 9.0 0.5 2.2 2 0 0 2 2 2 0 Autophagocytosis associated protein C-terminal WD40 PF00400.27 OAJ18175.1 - 7e-09 35.2 4.3 0.0046 16.7 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Macoilin PF09726.4 OAJ18175.1 - 1.1 7.4 4.4 1.6 6.8 0.4 2.4 2 0 0 2 2 2 0 Transmembrane protein Ldh_1_N PF00056.18 OAJ18201.1 - 0.0019 18.0 0.1 0.0028 17.5 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain MIP-T3 PF10243.4 OAJ18202.1 - 3.4 6.0 50.9 2 6.7 25.2 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Mem_trans PF03547.13 OAJ18202.1 - 7.7 4.6 6.2 12 4.0 4.3 1.4 1 0 0 1 1 1 0 Membrane transport protein GCR1_C PF12550.3 OAJ18204.1 - 2.1e-19 69.1 1.0 2.9e-19 68.6 0.7 1.2 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Suf PF05843.9 OAJ18204.1 - 0.36 10.5 2.7 0.69 9.5 0.1 2.2 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) Dus PF01207.12 OAJ18205.1 - 2e-47 161.5 0.0 2.9e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Dppa2_A PF14049.1 OAJ18207.1 - 0.012 15.4 0.8 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates Myosin_HC-like PF07058.6 OAJ18207.1 - 0.052 12.6 0.1 0.079 12.0 0.1 1.2 1 0 0 1 1 1 0 Myosin II heavy chain-like DUF3414 PF11894.3 OAJ18208.1 - 6e-247 822.4 11.2 7.1e-247 822.1 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) F-box PF00646.28 OAJ18209.1 - 0.0046 16.5 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ18209.1 - 0.034 13.8 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like Imm18 PF15566.1 OAJ18209.1 - 0.066 12.5 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 18 4HBT_3 PF13622.1 OAJ18210.1 - 4.2e-41 141.3 0.0 6.5e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 OAJ18210.1 - 9.7e-22 77.0 0.0 1.6e-18 66.6 0.0 2.9 2 1 0 2 2 2 2 Acyl-CoA thioesterase RVT_1 PF00078.22 OAJ18211.1 - 4.8e-19 68.5 0.0 8.3e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ18211.1 - 2.7e-15 56.5 0.0 6.8e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Serglycin PF04360.7 OAJ18238.1 - 0.14 11.9 1.0 0.25 11.0 0.7 1.3 1 0 0 1 1 1 0 Serglycin DUF4604 PF15377.1 OAJ18238.1 - 0.14 12.3 19.9 0.44 10.7 13.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) WD40 PF00400.27 OAJ18239.1 - 8.8e-25 85.6 10.8 1.1e-06 28.3 0.2 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat MFS_1 PF07690.11 OAJ18240.1 - 5.3e-37 127.3 36.6 5.3e-37 127.3 25.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ18240.1 - 8.5e-07 27.9 13.9 8.5e-07 27.9 9.7 2.5 3 1 0 3 3 3 1 Sugar (and other) transporter POX PF07526.6 OAJ18240.1 - 0.54 10.4 2.4 0.78 9.9 1.6 1.2 1 0 0 1 1 1 0 Associated with HOX vWA-TerF-like PF10138.4 OAJ18241.1 - 0.00084 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus T2SS-T3SS_pil_N PF13629.1 OAJ18241.1 - 0.058 12.9 0.1 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 Pilus formation protein N terminal region VWA_3 PF13768.1 OAJ18241.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.23 OAJ18241.1 - 0.076 12.7 0.1 0.39 10.4 0.1 2.0 1 1 0 1 1 1 0 von Willebrand factor type A domain DEAD PF00270.24 OAJ18242.1 - 1.1e-21 77.0 0.0 1.3e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ18242.1 - 0.16 11.8 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.24 OAJ18243.1 - 7e-19 68.3 0.0 4.8e-09 36.5 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 OAJ18243.1 - 2.1e-12 47.0 1.2 2.7e-11 43.4 0.9 2.3 1 1 0 1 1 1 1 BCS1 N terminal AAA_19 PF13245.1 OAJ18243.1 - 0.0049 16.5 0.0 0.017 14.8 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 OAJ18243.1 - 0.0057 16.8 0.1 0.048 13.8 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_11 PF13086.1 OAJ18243.1 - 0.007 15.9 0.0 0.026 14.0 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ18243.1 - 0.009 16.8 0.0 0.029 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ18243.1 - 0.019 14.9 0.8 0.1 12.5 0.2 2.7 1 1 1 2 2 2 0 AAA ATPase domain RuvB_N PF05496.7 OAJ18243.1 - 0.042 12.8 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus TMEM240 PF15207.1 OAJ18243.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 TMEM240 family Hist_deacetyl PF00850.14 OAJ18244.1 - 1.8e-51 175.3 0.0 2.6e-51 174.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain PIG-X PF08320.7 OAJ18245.1 - 6.5e-12 45.1 0.0 0.00059 19.1 0.0 3.4 3 1 0 3 3 3 3 PIG-X / PBN1 Med22 PF06179.7 OAJ18246.1 - 2.5e-13 49.9 0.2 3.7e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Brix PF04427.13 OAJ18247.1 - 4.2e-21 75.4 0.0 1.1e-20 74.1 0.0 1.6 1 1 0 1 1 1 1 Brix domain Nop14 PF04147.7 OAJ18247.1 - 0.66 7.8 36.7 0.94 7.3 25.4 1.2 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 OAJ18247.1 - 0.8 8.8 20.4 1.5 8.0 14.1 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 OAJ18247.1 - 2.6 6.4 29.0 4.3 5.7 20.1 1.4 1 0 0 1 1 1 0 Daxx Family Paf1 PF03985.8 OAJ18247.1 - 2.7 6.6 17.6 4.3 5.9 12.2 1.3 1 0 0 1 1 1 0 Paf1 WD40 PF00400.27 OAJ18277.1 - 0.011 15.6 0.1 2.6 8.0 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat S1 PF00575.18 OAJ18280.1 - 4.7e-38 129.1 7.4 2.9e-07 30.4 0.4 8.2 9 0 0 9 9 9 6 S1 RNA binding domain TPR_16 PF13432.1 OAJ18280.1 - 2.2e-09 37.7 1.2 0.00063 20.3 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat Suf PF05843.9 OAJ18280.1 - 2.8e-06 27.2 11.9 0.00015 21.6 0.0 3.7 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.1 OAJ18280.1 - 3.3e-06 27.3 0.0 1.8 8.9 0.0 4.0 3 1 0 3 3 3 3 Tetratricopeptide repeat NRDE-2 PF08424.5 OAJ18280.1 - 0.00012 21.0 3.8 0.011 14.6 0.8 3.2 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 OAJ18280.1 - 0.00043 20.6 1.2 3.9 8.3 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 OAJ18280.1 - 0.00061 18.9 1.8 0.0025 16.9 1.2 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ18280.1 - 0.011 16.0 0.3 3.8 8.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Nop14 PF04147.7 OAJ18280.1 - 0.56 8.0 57.6 0.042 11.7 1.1 3.4 3 0 0 3 3 3 0 Nop14-like family DUF2360 PF10152.4 OAJ18281.1 - 0.038 14.2 3.2 0.08 13.2 2.2 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Exo_endo_phos PF03372.18 OAJ18282.1 - 6.9e-19 68.7 0.5 9.7e-19 68.2 0.4 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MSP1_C PF07462.6 OAJ18282.1 - 0.58 8.4 0.5 1.1 7.5 0.4 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Ribosomal_L29 PF00831.18 OAJ18283.1 - 2.7e-19 68.6 3.9 2.7e-19 68.6 2.7 2.0 2 0 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 OAJ18283.1 - 0.025 14.8 2.1 0.033 14.4 1.4 1.3 1 0 0 1 1 1 0 Ribosomal protein S9/S16 DUF1013 PF06242.6 OAJ18283.1 - 0.2 11.6 2.3 0.3 11.0 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1013) DUF607 PF04678.8 OAJ18283.1 - 0.43 10.4 3.7 0.72 9.7 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF607 DUF896 PF05979.7 OAJ18283.1 - 6.3 6.4 7.7 0.58 9.8 1.5 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Peptidase_M18 PF02127.10 OAJ18284.1 - 1.3e-152 508.2 0.0 1.8e-152 507.8 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 OAJ18284.1 - 0.00042 19.1 0.0 0.1 11.3 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase RRM_6 PF14259.1 OAJ18285.1 - 8.1e-06 25.7 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ18285.1 - 0.008 15.7 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_11 PF08241.7 OAJ18286.1 - 2.7e-18 66.2 0.0 1.1e-17 64.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ18286.1 - 1.4e-15 57.1 0.0 2.1e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ18286.1 - 6e-12 46.1 0.0 1.3e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ18286.1 - 4.2e-11 43.1 0.0 1.2e-10 41.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ18286.1 - 1.1e-10 41.7 0.0 2.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ18286.1 - 1.2e-10 40.9 0.0 1.8e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 OAJ18286.1 - 1.9e-10 40.6 0.0 3.1e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ18286.1 - 6.6e-10 39.0 0.1 2.8e-09 37.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 OAJ18286.1 - 3.3e-05 23.3 0.0 0.00011 21.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 OAJ18286.1 - 0.00012 21.1 0.0 0.00037 19.5 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.11 OAJ18286.1 - 0.00014 20.4 0.0 0.00018 20.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPMT PF05724.6 OAJ18286.1 - 0.0002 20.8 0.0 0.0009 18.7 0.0 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.15 OAJ18286.1 - 0.0051 15.9 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 OAJ18286.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 OAJ18286.1 - 0.015 14.3 0.0 0.039 12.9 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.5 OAJ18286.1 - 0.023 14.2 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_8 PF05148.10 OAJ18286.1 - 0.13 11.9 0.0 3.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase PrmA PF06325.8 OAJ18286.1 - 0.19 10.7 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Transglut_core3 PF13471.1 OAJ18287.1 - 0.029 14.1 0.5 0.066 13.0 0.0 1.7 1 1 0 2 2 2 0 Transglutaminase-like superfamily BCL9 PF11502.3 OAJ18287.1 - 0.05 13.1 0.1 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 B-cell lymphoma 9 protein SlyX PF04102.7 OAJ18288.1 - 0.44 10.9 0.1 0.44 10.9 0.1 2.8 3 0 0 3 3 3 0 SlyX zf-C2H2 PF00096.21 OAJ18288.1 - 0.53 10.7 4.5 2.2 8.8 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ18288.1 - 9.5 6.8 7.6 1.3 9.4 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger VirB3 PF05101.8 OAJ18321.1 - 0.017 15.0 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Brix PF04427.13 OAJ18325.1 - 3.2e-48 163.9 0.0 4e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Brix domain SE PF08491.5 OAJ18326.1 - 1.1e-80 270.4 0.0 6.2e-37 126.9 0.0 3.2 3 0 0 3 3 3 3 Squalene epoxidase DAO PF01266.19 OAJ18326.1 - 4.6e-13 48.8 2.2 4.2e-09 35.7 0.3 2.8 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAJ18326.1 - 6.9e-10 38.5 0.6 6.3e-06 25.4 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 OAJ18326.1 - 2.4e-07 30.8 0.0 3.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAJ18326.1 - 4.1e-05 23.5 0.9 0.0001 22.2 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 OAJ18326.1 - 0.00024 20.5 0.2 0.00053 19.4 0.2 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 OAJ18326.1 - 0.00029 20.5 0.1 0.0005 19.7 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 OAJ18326.1 - 0.00032 19.8 0.1 0.0005 19.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 OAJ18326.1 - 0.00061 18.7 0.8 0.00087 18.2 0.3 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 OAJ18326.1 - 0.00067 18.6 2.4 0.0022 16.9 1.1 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 OAJ18326.1 - 0.0011 18.0 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 OAJ18326.1 - 0.0019 17.9 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 OAJ18326.1 - 0.0019 18.5 0.4 0.0057 17.0 0.1 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 OAJ18326.1 - 0.0021 16.7 0.8 0.02 13.5 0.1 2.1 1 1 1 2 2 2 1 Tryptophan halogenase ThiF PF00899.16 OAJ18326.1 - 0.0054 16.5 0.1 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 OAJ18326.1 - 0.0085 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 OAJ18326.1 - 0.015 14.3 0.2 0.022 13.7 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Lycopene_cycl PF05834.7 OAJ18326.1 - 0.016 14.1 1.1 0.043 12.7 0.3 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein F420_oxidored PF03807.12 OAJ18326.1 - 0.084 13.3 0.1 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HI0933_like PF03486.9 OAJ18326.1 - 0.097 11.1 0.1 0.15 10.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_2 PF03446.10 OAJ18326.1 - 0.12 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GDI PF00996.13 OAJ18326.1 - 0.15 10.3 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Med10 PF09748.4 OAJ18327.1 - 5.6e-15 55.2 0.0 7e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex EMG1 PF03587.9 OAJ18328.1 - 3.9e-75 251.5 0.0 5e-75 251.2 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase RNase_PH PF01138.16 OAJ18329.1 - 2.5e-22 79.6 0.0 4.1e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Arf PF00025.16 OAJ18330.1 - 3.5e-77 257.5 0.0 4e-77 257.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 OAJ18330.1 - 6.2e-13 48.4 0.0 6.7e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 OAJ18330.1 - 2e-11 43.4 0.0 2.5e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 OAJ18330.1 - 2.6e-11 42.8 0.8 2.6e-07 29.7 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 OAJ18330.1 - 4.3e-10 39.1 0.0 5.2e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 OAJ18330.1 - 1.3e-07 32.0 0.0 1.8e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 OAJ18330.1 - 0.00013 21.9 0.0 0.00032 20.6 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 OAJ18330.1 - 0.00083 18.4 0.1 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 OAJ18330.1 - 0.013 14.9 0.0 0.098 12.0 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PP2C PF00481.16 OAJ18331.1 - 8.4e-68 228.5 0.4 1.1e-51 175.6 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C BAR PF03114.13 OAJ18332.1 - 1.7e-11 44.0 1.4 2.9e-11 43.3 1.0 1.3 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 OAJ18332.1 - 0.00015 20.7 0.2 0.0003 19.8 0.2 1.5 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Acetyltransf_5 PF13444.1 OAJ18333.1 - 0.0001 22.7 0.0 0.00074 20.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAJ18333.1 - 0.072 13.1 0.2 0.16 11.9 0.1 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Methyltransf_31 PF13847.1 OAJ18335.1 - 2.2e-17 63.0 0.0 3.2e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ18335.1 - 3.5e-14 53.0 0.0 6.3e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ18335.1 - 2.5e-13 50.6 0.0 4.5e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ18335.1 - 2.1e-12 47.3 0.0 3.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ18335.1 - 6.1e-10 39.0 0.0 9.1e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ18335.1 - 1.4e-08 34.7 0.1 2.7e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ18335.1 - 8.9e-08 32.4 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ18335.1 - 2.6e-06 26.8 0.0 8.1e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 OAJ18335.1 - 3.8e-06 26.5 0.0 6.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PCMT PF01135.14 OAJ18335.1 - 4.7e-06 26.2 0.0 7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 OAJ18335.1 - 6.8e-05 22.0 0.0 9.1e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 OAJ18335.1 - 0.00021 20.5 0.0 0.00029 20.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 OAJ18335.1 - 0.0019 17.2 0.0 0.0042 16.2 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 OAJ18335.1 - 0.0045 16.6 0.0 0.0066 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 OAJ18335.1 - 0.02 14.1 0.0 2.5 7.3 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain CAV_VP3 PF04771.7 OAJ18335.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 1 0 Chicken anaemia virus VP-3 protein RrnaAD PF00398.15 OAJ18335.1 - 0.061 12.3 0.0 0.099 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase N6_Mtase PF02384.11 OAJ18335.1 - 0.069 12.2 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_9 PF08003.6 OAJ18335.1 - 0.085 11.5 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RVT_2 PF07727.9 OAJ18360.1 - 1.1e-87 293.0 0.0 1.5e-87 292.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 OAJ18361.1 - 1.5e-07 31.1 0.0 3.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 OAJ18361.1 - 2.5e-06 27.4 0.0 5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAJ18361.1 - 3.7e-06 27.3 0.0 8.3e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 OAJ18361.1 - 0.00015 21.5 3.0 0.00027 20.6 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 OAJ18361.1 - 0.0011 18.6 0.5 0.0038 16.8 0.4 1.9 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 OAJ18361.1 - 0.009 16.0 0.7 0.067 13.2 0.0 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 OAJ18361.1 - 0.022 14.5 0.2 0.052 13.2 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ18361.1 - 0.1 12.2 1.2 0.28 10.8 0.3 2.1 2 0 0 2 2 2 0 Zinc knuckle Myb_DNA-bind_5 PF13873.1 OAJ18362.1 - 0.0014 18.4 0.2 0.015 15.1 0.2 2.2 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ18362.1 - 0.026 14.6 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Nop14 PF04147.7 OAJ18362.1 - 0.046 11.6 11.5 0.057 11.3 8.0 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 OAJ18362.1 - 0.19 10.7 6.0 0.22 10.5 4.1 1.1 1 0 0 1 1 1 0 BUD22 FYDLN_acid PF09538.5 OAJ18362.1 - 0.37 11.4 15.7 0.64 10.6 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SDA1 PF05285.7 OAJ18362.1 - 2.3 7.3 13.4 3 7.0 9.3 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 OAJ18362.1 - 5.6 4.8 7.6 6.9 4.5 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-CCHC PF00098.18 OAJ18363.1 - 1.6e-06 27.7 3.0 4.4e-06 26.3 2.1 1.8 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 OAJ18363.1 - 2.6e-06 27.2 0.0 6.8e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Daxx PF03344.10 OAJ18363.1 - 0.014 13.9 8.3 0.025 13.0 5.7 1.3 1 0 0 1 1 1 0 Daxx Family Glyco_tranf_2_2 PF10111.4 OAJ18363.1 - 0.21 10.6 0.0 0.78 8.7 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 rve PF00665.21 OAJ18364.1 - 2.3e-15 56.7 0.0 1.2e-14 54.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ18364.1 - 1e-12 47.8 0.1 2.7e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 OAJ18364.1 - 0.0008 19.0 0.7 0.0026 17.4 0.2 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 OAJ18366.1 - 5e-09 35.8 0.0 1.8e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ18366.1 - 9e-05 22.2 0.0 0.025 14.4 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain rve PF00665.21 OAJ18395.1 - 3.5e-15 56.1 0.0 3.7e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain Transcript_VP30 PF11507.3 OAJ18395.1 - 0.013 15.2 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 gag_pre-integrs PF13976.1 OAJ18396.1 - 4.2e-05 23.1 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 OAJ18396.1 - 0.0044 16.7 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ18396.1 - 1 9.4 6.7 2 8.4 4.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ18396.1 - 4.5 7.0 5.9 6.4 6.5 2.8 2.0 2 0 0 2 2 2 0 Zinc knuckle Bac_luciferase PF00296.15 OAJ18399.1 - 0.26 10.3 2.7 0.31 10.1 1.8 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase DUF883 PF05957.8 OAJ18399.1 - 3.1 8.2 10.0 7.8 6.9 2.7 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) EMA PF02488.10 OAJ18400.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Merozoite Antigen 2OG-FeII_Oxy_2 PF13532.1 OAJ18433.1 - 2.5e-26 92.7 0.0 4.1e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ18433.1 - 0.0052 17.0 0.0 0.026 14.8 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Med3 PF11593.3 OAJ18433.1 - 1.1 8.3 3.4 1.8 7.7 2.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HSP90 PF00183.13 OAJ18434.1 - 8.5e-59 199.3 1.5 1e-36 126.4 0.7 2.2 1 1 1 2 2 2 2 Hsp90 protein Scm3 PF10384.4 OAJ18434.1 - 1.4e-07 30.9 0.5 1.1e-06 28.0 0.4 2.2 2 0 0 2 2 2 1 Centromere protein Scm3 F_actin_cap_B PF01115.12 OAJ18435.1 - 6.7e-86 287.4 0.0 8e-86 287.1 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit TRAM_LAG1_CLN8 PF03798.11 OAJ18436.1 - 4.4e-39 134.1 18.1 5.4e-39 133.7 12.5 1.1 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 OAJ18436.1 - 0.00027 20.3 2.0 0.00031 20.1 0.0 2.0 2 0 0 2 2 2 1 TRAM1-like protein DUF4011 PF13195.1 OAJ18436.1 - 0.082 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) WD40 PF00400.27 OAJ18437.1 - 7.1e-16 57.4 6.4 1e-05 25.2 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.1 OAJ18437.1 - 3.4e-06 27.1 0.8 0.00055 20.1 0.0 4.0 3 0 0 3 3 3 1 PQQ-like domain Serglycin PF04360.7 OAJ18437.1 - 0.036 13.7 0.4 0.091 12.4 0.3 1.6 1 0 0 1 1 1 0 Serglycin HTH_Tnp_Tc5 PF03221.11 OAJ18438.1 - 1.9e-06 27.5 0.1 3.5e-05 23.5 0.0 2.3 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain HTH_26 PF13443.1 OAJ18438.1 - 0.038 14.1 0.1 0.98 9.6 0.0 2.5 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain DUF2201_N PF13203.1 OAJ18439.1 - 0.0083 15.3 0.9 0.0093 15.1 0.7 1.0 1 0 0 1 1 1 1 Putative metallopeptidase domain Herpes_IE1 PF07340.6 OAJ18439.1 - 0.039 12.4 0.1 0.039 12.4 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein Ribosomal_S10 PF00338.17 OAJ18462.1 - 1.2e-19 69.8 0.0 2.1e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e NAD_binding_8 PF13450.1 OAJ18464.1 - 2e-12 46.9 0.1 4.3e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ18464.1 - 7.9e-12 44.7 1.0 9e-11 41.2 0.7 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 OAJ18464.1 - 7.7e-07 28.5 0.2 2.3e-05 23.6 0.1 2.7 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 OAJ18464.1 - 1.3e-05 25.2 0.0 3.1e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAJ18464.1 - 3.4e-05 22.8 1.0 8.3e-05 21.6 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 OAJ18464.1 - 0.00016 21.9 3.7 0.00067 20.0 0.8 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ18464.1 - 0.0021 16.6 0.2 0.003 16.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 OAJ18464.1 - 0.0034 16.4 1.0 0.0068 15.5 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 OAJ18464.1 - 0.0052 16.3 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 OAJ18464.1 - 0.0087 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 OAJ18464.1 - 0.01 14.4 0.9 1.2 7.6 0.3 2.2 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.13 OAJ18464.1 - 0.016 15.1 0.1 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 OAJ18464.1 - 0.023 13.8 0.2 0.044 12.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 OAJ18464.1 - 0.028 13.8 0.4 0.056 12.8 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 OAJ18464.1 - 0.044 12.6 0.1 0.081 11.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Rossmann-like PF10727.4 OAJ18464.1 - 0.074 12.7 0.2 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 OAJ18464.1 - 0.086 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 OAJ18464.1 - 0.1 11.6 0.1 0.2 10.7 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 OAJ18464.1 - 0.11 12.1 0.3 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 OAJ18464.1 - 0.17 11.6 0.7 0.35 10.6 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 OAJ18464.1 - 0.17 12.1 0.2 0.98 9.7 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 OAJ18464.1 - 0.22 10.3 3.5 0.2 10.4 0.5 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A AA_permease_2 PF13520.1 OAJ18465.1 - 1.9e-77 260.6 34.0 2.5e-77 260.2 23.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAJ18465.1 - 2.9e-20 72.0 30.3 3.9e-20 71.6 17.9 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 OAJ18466.1 - 3.2e-43 147.8 21.0 4e-43 147.5 14.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAJ18466.1 - 1.8e-11 43.0 19.2 2.3e-11 42.7 13.3 1.0 1 0 0 1 1 1 1 Amino acid permease RhoGEF PF00621.15 OAJ18467.1 - 2.8e-31 108.7 0.0 4.3e-26 91.8 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain DUF4547 PF15080.1 OAJ18467.1 - 1.8 7.9 0.0 3.1 7.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4547) 3-HAO PF06052.7 OAJ18468.1 - 7.9e-59 197.3 0.0 9.1e-59 197.2 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 OAJ18468.1 - 3.1e-07 29.7 0.1 4.5e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 OAJ18468.1 - 0.00033 20.1 0.0 0.00048 19.5 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 OAJ18468.1 - 0.035 13.7 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain ARD PF03079.9 OAJ18468.1 - 0.064 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family DEAD PF00270.24 OAJ18469.1 - 2e-13 50.1 0.0 4.7e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ18469.1 - 0.002 17.9 0.0 0.002 17.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_23 PF13476.1 OAJ18469.1 - 0.057 13.7 6.6 0.1 12.9 4.6 1.3 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.4 OAJ18469.1 - 0.6 9.5 9.8 1.2 8.5 6.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BRF1 PF07741.8 OAJ18469.1 - 1.2 9.4 11.6 0.12 12.6 4.0 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain OATP PF03137.15 OAJ18469.1 - 2.5 6.0 5.7 4.4 5.2 3.9 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Serinc PF03348.10 OAJ18469.1 - 5.7 5.5 7.9 10 4.6 5.5 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) Metallopep PF12044.3 OAJ18470.1 - 3.7e-10 38.8 0.0 2e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 Putative peptidase family Phage_integrase PF00589.17 OAJ18471.1 - 6.5e-06 25.9 0.0 1.6e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Phage integrase family RNase_H PF00075.19 OAJ18471.1 - 0.00025 21.3 0.0 0.0005 20.4 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAJ18471.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like PhyH PF05721.8 OAJ18500.1 - 3.6e-08 33.7 0.0 1.3e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1325 PF07039.6 OAJ18501.1 - 1.3e-28 99.1 0.0 1.9e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain GvpG PF05120.7 OAJ18501.1 - 0.73 9.6 4.6 15 5.4 0.1 3.5 4 0 0 4 4 4 0 Gas vesicle protein G PGM_PMM_I PF02878.11 OAJ18502.1 - 3.3e-38 130.2 0.3 5.6e-38 129.5 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 OAJ18502.1 - 4.8e-23 81.4 0.1 1.6e-22 79.7 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 OAJ18502.1 - 6.9e-09 35.7 0.0 1.5e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 OAJ18502.1 - 1.8e-07 31.0 0.1 8.1e-07 28.9 0.0 2.2 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain SR-25 PF10500.4 OAJ18502.1 - 1.1 8.6 9.6 2.1 7.7 6.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GATA PF00320.22 OAJ18503.1 - 3e-12 45.6 5.7 5.7e-12 44.7 3.9 1.5 1 0 0 1 1 1 1 GATA zinc finger FAM163 PF15069.1 OAJ18503.1 - 3.8 8.0 5.5 1.3 9.6 0.0 2.8 2 1 1 3 3 3 0 FAM163 family zf-RING_2 PF13639.1 OAJ18504.1 - 1.8e-07 30.8 4.6 1.8e-07 30.8 3.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAJ18504.1 - 0.00011 21.8 1.7 0.00011 21.8 1.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 OAJ18504.1 - 0.00012 22.0 10.4 0.00087 19.3 7.2 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 OAJ18504.1 - 0.00042 20.2 2.0 0.0011 18.9 1.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ18504.1 - 0.0012 18.4 2.8 0.0012 18.4 2.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ18504.1 - 0.0056 16.3 2.9 0.0056 16.3 2.0 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 OAJ18504.1 - 0.016 15.0 1.0 0.041 13.7 0.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 OAJ18504.1 - 0.073 12.8 0.7 0.18 11.6 0.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Pyridox_oxidase PF01243.15 OAJ18505.1 - 0.0093 15.9 0.0 0.9 9.5 0.0 3.1 3 0 0 3 3 3 1 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 OAJ18505.1 - 0.028 14.5 0.0 0.26 11.4 0.0 2.5 2 1 0 2 2 2 0 Oxidoreductase FAD-binding domain TP_methylase PF00590.15 OAJ18505.1 - 0.065 12.9 0.2 5.6 6.6 0.0 2.8 3 0 0 3 3 3 0 Tetrapyrrole (Corrin/Porphyrin) Methylases MIF4G PF02854.14 OAJ18506.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 MIF4G domain DUF543 PF04418.7 OAJ18507.1 - 2.7e-28 97.7 0.2 6.8e-28 96.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF543) WT1 PF02165.10 OAJ18507.1 - 0.11 11.5 0.2 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 Wilm's tumour protein DUF883 PF05957.8 OAJ18507.1 - 0.11 12.8 4.4 1.2 9.5 0.2 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) AAA PF00004.24 OAJ18508.1 - 3.3e-84 279.7 0.0 9.7e-42 142.3 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAJ18508.1 - 5.4e-14 52.0 0.1 3.2e-06 26.9 0.0 4.7 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 OAJ18508.1 - 5.5e-13 48.4 0.0 4.1e-06 26.0 0.0 3.0 4 0 0 4 4 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 OAJ18508.1 - 2.2e-12 47.3 1.1 0.00072 19.5 0.1 3.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 OAJ18508.1 - 5e-11 42.8 0.1 0.00012 22.2 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 OAJ18508.1 - 1.2e-09 38.9 0.0 0.00017 22.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAJ18508.1 - 2e-08 33.8 4.2 0.017 14.4 0.1 4.6 3 2 1 4 4 3 2 AAA domain TIP49 PF06068.8 OAJ18508.1 - 6.3e-08 31.7 0.1 0.00037 19.3 0.0 2.5 3 0 0 3 3 3 2 TIP49 C-terminus AAA_19 PF13245.1 OAJ18508.1 - 1.1e-07 31.5 1.3 0.00012 21.7 0.0 4.0 2 1 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 OAJ18508.1 - 1.5e-07 31.3 0.0 0.0032 17.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 OAJ18508.1 - 3.3e-07 29.5 0.0 0.00054 19.1 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_2 PF07724.9 OAJ18508.1 - 1e-06 28.7 0.0 0.041 13.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 OAJ18508.1 - 1.4e-06 27.8 0.0 0.02 14.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.1 OAJ18508.1 - 5.9e-06 26.2 0.0 0.0055 16.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 OAJ18508.1 - 2.6e-05 24.3 0.0 0.32 11.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 OAJ18508.1 - 3.2e-05 23.2 2.5 0.084 12.0 0.0 2.8 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 OAJ18508.1 - 6.6e-05 22.9 0.1 0.14 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 OAJ18508.1 - 0.00011 22.4 0.0 0.0068 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 OAJ18508.1 - 0.00025 21.1 0.0 0.3 11.1 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 OAJ18508.1 - 0.00047 19.8 0.1 0.041 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 OAJ18508.1 - 0.0011 17.7 0.1 0.19 10.3 0.0 3.0 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 OAJ18508.1 - 0.0018 17.9 0.0 4 7.0 0.0 3.4 3 1 1 4 4 3 1 NACHT domain AAA_3 PF07726.6 OAJ18508.1 - 0.0028 17.2 0.0 2 8.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 OAJ18508.1 - 0.0028 16.7 0.0 1.8 7.5 0.0 3.1 4 0 0 4 4 3 1 KaiC Sigma54_activat PF00158.21 OAJ18508.1 - 0.0042 16.5 0.2 6.7 6.1 0.0 3.9 3 1 0 3 3 3 0 Sigma-54 interaction domain NTPase_1 PF03266.10 OAJ18508.1 - 0.0048 16.6 0.4 0.84 9.3 0.0 3.8 2 2 2 4 4 4 1 NTPase ABC_tran PF00005.22 OAJ18508.1 - 0.0094 16.2 0.0 0.73 10.1 0.0 3.0 2 0 0 2 2 2 1 ABC transporter ATP-synt_ab PF00006.20 OAJ18508.1 - 0.0097 15.4 0.1 5.7 6.3 0.0 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.1 OAJ18508.1 - 0.011 15.3 0.0 0.26 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 OAJ18508.1 - 0.013 14.7 0.3 0.51 9.5 0.0 2.6 3 0 0 3 3 2 0 PhoH-like protein Parvo_NS1 PF01057.12 OAJ18508.1 - 0.023 13.5 0.0 3.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 OAJ18508.1 - 0.037 13.7 0.0 8.3 6.0 0.0 3.2 2 1 1 3 3 3 0 Archaeal ATPase SKI PF01202.17 OAJ18508.1 - 0.066 13.0 0.0 9.7 6.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase DUF815 PF05673.8 OAJ18508.1 - 0.16 10.8 0.0 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DAP3 PF10236.4 OAJ18508.1 - 0.19 10.6 0.0 0.65 8.8 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Peptidase_M13_N PF05649.8 OAJ18509.1 - 7.6e-88 295.1 0.0 9.4e-88 294.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 OAJ18509.1 - 1e-54 184.8 0.0 1.6e-54 184.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 DUF605 PF04652.11 OAJ18509.1 - 0.026 13.9 2.0 0.04 13.3 1.4 1.3 1 0 0 1 1 1 0 Vta1 like Ribosomal_S18 PF01084.15 OAJ18509.1 - 0.55 10.1 1.9 7 6.6 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S18 YadA_head PF05658.9 OAJ18509.1 - 0.57 10.5 1.8 1.3 9.4 1.3 1.6 1 0 0 1 1 1 0 Head domain of trimeric autotransporter adhesin DUF2040 PF09745.4 OAJ18510.1 - 3.4e-30 104.4 21.0 3.4e-30 104.4 14.6 2.8 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Transferase PF02458.10 OAJ18510.1 - 0.094 11.1 1.5 0.12 10.7 1.1 1.3 1 0 0 1 1 1 0 Transferase family CENP-I PF07778.6 OAJ18510.1 - 0.12 10.5 1.0 0.22 9.6 0.7 1.3 1 0 0 1 1 1 0 Mis6 CAF-1_p150 PF11600.3 OAJ18510.1 - 0.47 9.7 32.7 0.5 9.7 6.2 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal tRNA-synt_1 PF00133.17 OAJ18532.1 - 1.9e-18 65.8 0.1 2.2e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Zn_clus PF00172.13 OAJ18534.1 - 2.8e-05 23.9 8.0 5e-05 23.1 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF572 PF04502.8 OAJ18534.1 - 4 6.5 14.9 0.38 9.9 6.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) tRNA-synt_1 PF00133.17 OAJ18535.1 - 1.7e-112 376.4 0.0 2e-112 376.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) PUB PF09409.5 OAJ18535.1 - 0.069 12.9 0.7 0.13 12.0 0.5 1.5 1 0 0 1 1 1 0 PUB domain PITH PF06201.8 OAJ18536.1 - 1.7e-38 131.7 0.0 1.5e-18 67.0 0.0 3.3 3 0 0 3 3 3 3 PITH domain Anticodon_1 PF08264.8 OAJ18536.1 - 0.015 15.0 0.0 0.037 13.7 0.0 1.6 1 1 0 1 1 1 0 Anticodon-binding domain of tRNA FTA2 PF13095.1 OAJ18536.1 - 0.043 13.3 0.0 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Shisa PF13908.1 OAJ18536.1 - 0.1 12.8 2.4 5.9 7.0 0.1 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Cyclin_N PF00134.18 OAJ18537.1 - 2.3e-11 43.3 0.0 4.1e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 OAJ18537.1 - 0.023 14.4 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIIB repeat E2_bind PF08825.5 OAJ18538.1 - 0.076 12.7 0.6 0.13 12.0 0.4 1.4 1 0 0 1 1 1 0 E2 binding domain TBPIP PF07106.8 OAJ18538.1 - 0.2 11.1 1.8 1.7 8.1 0.8 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DPBB_1 PF03330.13 OAJ18539.1 - 3.2e-05 23.8 0.0 7.2e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ18539.1 - 0.0025 17.4 0.2 0.0046 16.6 0.1 1.3 1 1 0 1 1 1 1 Barwin family RRM_1 PF00076.17 OAJ18564.1 - 9.2e-26 89.2 0.0 3.2e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ18564.1 - 1.1e-16 60.5 0.0 2.2e-08 33.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ18564.1 - 0.068 13.0 0.0 5 7.0 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX14 PF14880.1 OAJ18565.1 - 0.0028 17.2 0.2 0.0048 16.4 0.1 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c assembly DUF2530 PF10745.4 OAJ18565.1 - 0.072 13.0 0.2 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Pro_dh-DNA_bdg PF14850.1 OAJ18565.1 - 0.15 12.2 0.0 0.19 11.9 0.0 1.1 1 0 0 1 1 1 0 DNA-binding domain of Proline dehydrogenase AAA PF00004.24 OAJ18566.1 - 2.2e-17 63.5 0.0 8.3e-17 61.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 OAJ18566.1 - 1.5e-16 60.1 0.0 2.8e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 OAJ18566.1 - 3.3e-16 59.3 0.0 2.2e-14 53.4 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 OAJ18566.1 - 2.9e-11 42.7 0.0 1e-08 34.3 0.0 2.2 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 OAJ18566.1 - 3.6e-06 27.1 0.2 0.015 15.4 0.0 2.7 2 1 1 3 3 2 2 AAA domain RuvB_N PF05496.7 OAJ18566.1 - 1.2e-05 24.4 0.0 2.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 OAJ18566.1 - 3e-05 23.9 0.0 8.4e-05 22.4 0.0 1.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 OAJ18566.1 - 3.4e-05 22.8 0.0 5.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.8 OAJ18566.1 - 4.2e-05 23.1 0.0 0.00011 21.7 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_11 PF13086.1 OAJ18566.1 - 6e-05 22.7 0.2 0.0036 16.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 OAJ18566.1 - 6.2e-05 22.7 0.1 0.00024 20.8 0.0 2.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 OAJ18566.1 - 0.00011 21.8 0.0 0.00036 20.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 OAJ18566.1 - 0.00019 21.4 0.0 0.0031 17.5 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_3 PF07726.6 OAJ18566.1 - 0.00031 20.3 0.0 0.00064 19.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 OAJ18566.1 - 0.00054 19.4 0.3 0.38 10.1 0.0 2.4 1 1 1 2 2 2 2 AAA-like domain AAA_25 PF13481.1 OAJ18566.1 - 0.0014 18.1 0.0 0.0075 15.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 OAJ18566.1 - 0.0016 18.0 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 OAJ18566.1 - 0.0017 17.9 0.0 0.0044 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 OAJ18566.1 - 0.0069 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 OAJ18566.1 - 0.017 14.5 0.1 0.24 10.8 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase T2SE PF00437.15 OAJ18566.1 - 0.021 13.7 0.0 0.039 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.10 OAJ18566.1 - 0.031 14.0 0.0 0.25 11.1 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.13 OAJ18566.1 - 0.032 13.7 0.0 0.082 12.3 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 OAJ18566.1 - 0.042 14.1 0.0 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter IstB_IS21 PF01695.12 OAJ18566.1 - 0.054 12.9 0.0 0.19 11.1 0.0 1.9 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 OAJ18566.1 - 0.092 12.6 0.0 0.18 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 OAJ18566.1 - 0.098 11.8 0.0 0.37 9.9 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 OAJ18566.1 - 0.1 12.1 0.0 0.32 10.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 OAJ18566.1 - 0.12 12.3 0.0 0.31 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain TIP41 PF04176.8 OAJ18567.1 - 1.6e-43 148.0 0.0 1.4e-39 135.2 0.0 2.5 2 1 0 2 2 2 2 TIP41-like family Nop14 PF04147.7 OAJ18568.1 - 0.014 13.3 14.4 0.02 12.8 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3682 PF12446.3 OAJ18568.1 - 0.097 12.9 12.5 4.5 7.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) Sporozoite_P67 PF05642.6 OAJ18568.1 - 0.18 9.6 2.4 0.27 9.0 1.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.8 OAJ18568.1 - 0.28 10.7 11.6 0.7 9.4 8.0 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Rpp20 PF12328.3 OAJ18568.1 - 0.72 9.5 5.4 0.091 12.4 0.7 1.7 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P RR_TM4-6 PF06459.7 OAJ18568.1 - 2.7 7.7 6.3 4.1 7.2 4.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 VID27 PF08553.5 OAJ18568.1 - 5.8 4.9 9.6 0.71 8.0 3.4 1.7 2 0 0 2 2 2 0 VID27 cytoplasmic protein TRAP_alpha PF03896.11 OAJ18568.1 - 7.7 5.4 6.9 13 4.6 4.8 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Mcp5_PH PF12814.2 OAJ18569.1 - 2.6e-40 137.1 0.2 1.2e-39 135.0 0.0 2.2 2 1 1 3 3 3 1 Meiotic cell cortex C-terminal pleckstrin homology DUF3166 PF11365.3 OAJ18569.1 - 0.013 15.9 2.4 0.013 15.9 1.7 7.4 4 2 2 8 8 8 0 Protein of unknown function (DUF3166) Filament PF00038.16 OAJ18569.1 - 1.7 8.0 101.9 0.4 10.1 6.3 6.4 2 2 3 5 5 5 0 Intermediate filament protein DUF2890 PF11081.3 OAJ18570.1 - 0.097 12.7 0.1 0.097 12.7 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2890) INCENP_ARK-bind PF03941.10 OAJ18571.1 - 1.5e-07 31.1 0.2 4e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region DNA_primase_S PF01896.14 OAJ18572.1 - 1.2e-52 177.5 0.0 2e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit HTH_36 PF13730.1 OAJ18572.1 - 0.034 14.2 0.1 0.37 10.9 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Ctr PF04145.10 OAJ18573.1 - 5.4e-20 71.9 0.8 1.9e-18 66.8 0.5 2.1 1 1 0 1 1 1 1 Ctr copper transporter family RVT_1 PF00078.22 OAJ18574.1 - 1.2e-11 44.3 0.0 2e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CBFD_NFYB_HMF PF00808.18 OAJ18575.1 - 8.3e-08 32.1 0.3 1.4e-07 31.4 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BUD22 PF09073.5 OAJ18575.1 - 0.0017 17.4 18.3 0.0021 17.1 12.7 1.3 1 0 0 1 1 1 1 BUD22 Peptidase_S49_N PF08496.5 OAJ18575.1 - 0.023 14.4 0.8 0.023 14.4 0.6 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CDC27 PF09507.5 OAJ18575.1 - 0.11 11.7 18.9 0.12 11.5 13.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.8 OAJ18575.1 - 0.12 12.2 15.7 0.16 11.8 10.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pox_Ag35 PF03286.9 OAJ18575.1 - 0.16 11.4 20.1 0.19 11.2 7.0 2.4 1 1 1 2 2 2 0 Pox virus Ag35 surface protein CENP-T PF15511.1 OAJ18575.1 - 4.5 6.3 28.0 15 4.6 19.4 2.0 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 OAJ18575.1 - 7.4 4.9 32.7 14 4.0 22.6 1.4 1 0 0 1 1 1 0 Daxx Family GRAB PF10375.4 OAJ18576.1 - 3.4e-05 23.3 0.7 3.4e-05 23.3 0.5 2.5 2 0 0 2 2 2 1 GRIP-related Arf-binding domain Macoilin PF09726.4 OAJ18576.1 - 0.00029 19.2 4.2 0.00029 19.2 2.9 3.9 3 1 1 4 4 3 1 Transmembrane protein TMF_DNA_bd PF12329.3 OAJ18576.1 - 0.00087 19.0 1.9 0.00087 19.0 1.3 4.8 2 2 2 5 5 5 1 TATA element modulatory factor 1 DNA binding FliJ PF02050.11 OAJ18576.1 - 0.031 14.3 43.1 0.22 11.5 6.4 3.4 1 1 2 3 3 3 0 Flagellar FliJ protein IncA PF04156.9 OAJ18576.1 - 0.15 11.6 49.4 0.017 14.7 10.9 3.3 2 1 1 3 3 3 0 IncA protein DUF812 PF05667.6 OAJ18576.1 - 0.58 8.6 29.4 0.83 8.0 5.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Myosin_tail_1 PF01576.14 OAJ18576.1 - 1.3 6.6 43.6 0.027 12.2 21.3 2.1 2 0 0 2 2 2 0 Myosin tail Bacillus_HBL PF05791.6 OAJ18576.1 - 1.9 7.8 8.9 0.73 9.1 0.7 2.4 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Reo_sigmaC PF04582.7 OAJ18576.1 - 2 7.5 16.1 4 6.5 8.3 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 OAJ18576.1 - 2.6 6.3 18.6 0.71 8.2 9.0 2.1 2 0 0 2 2 2 0 AAA domain Baculo_PEP_C PF04513.7 OAJ18576.1 - 4.4 7.1 13.5 6.1 6.6 0.3 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 OAJ18576.1 - 6.5 6.5 41.9 0.029 14.2 7.9 3.3 2 1 1 3 3 2 0 Tropomyosin like Serine_rich PF08824.5 OAJ18606.1 - 0.072 12.8 0.3 0.16 11.6 0.2 1.6 1 1 0 1 1 1 0 Serine rich protein interaction domain KCl_Cotrans_1 PF03522.10 OAJ18606.1 - 0.89 9.1 3.5 4 7.0 2.4 2.2 1 1 0 1 1 1 0 K-Cl Co-transporter type 1 (KCC1) MARVEL PF01284.18 OAJ18607.1 - 1.5e-07 31.3 16.8 2.3e-07 30.7 11.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF3784 PF12650.2 OAJ18607.1 - 8.6 6.3 8.6 0.49 10.3 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF621 PF04789.10 OAJ18608.1 - 4.9 6.0 8.6 4.7 6.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF621) SQS_PSY PF00494.14 OAJ18610.1 - 3.8e-36 124.7 0.0 7.9e-36 123.7 0.0 1.6 1 0 0 1 1 1 1 Squalene/phytoene synthase Coatomer_WDAD PF04053.9 OAJ18611.1 - 1.2e-139 465.9 0.0 2e-139 465.2 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 OAJ18611.1 - 2.6e-78 263.4 0.0 3.9e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 OAJ18611.1 - 3.2e-51 169.4 10.1 4.4e-11 42.2 0.0 8.1 9 0 0 9 9 9 6 WD domain, G-beta repeat Clathrin PF00637.15 OAJ18611.1 - 0.011 15.3 0.1 0.026 14.1 0.1 1.6 1 0 0 1 1 1 0 Region in Clathrin and VPS Nup160 PF11715.3 OAJ18611.1 - 0.018 13.2 5.3 0.12 10.4 0.1 3.0 1 1 2 3 3 3 0 Nucleoporin Nup120/160 TPR_2 PF07719.12 OAJ18611.1 - 0.092 12.7 0.1 12 6.1 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Neur_chan_memb PF02932.11 OAJ18612.1 - 1.6 8.5 4.6 2.5 7.9 3.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DNA_pol_viral_N PF00242.12 OAJ18612.1 - 6.5 5.6 15.2 12 4.8 10.5 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Peptidase_M20 PF01546.23 OAJ18613.1 - 4.6e-29 101.2 0.0 7.9e-29 100.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 OAJ18613.1 - 8.1e-15 54.5 0.0 1.3e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Alk_phosphatase PF00245.15 OAJ18614.1 - 1.4e-79 267.8 0.0 3.8e-79 266.3 0.0 1.6 1 1 0 1 1 1 1 Alkaline phosphatase AAA PF00004.24 OAJ18615.1 - 5.1e-41 139.9 0.0 1.1e-40 138.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ18615.1 - 1.5e-05 25.1 0.0 0.0011 19.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAJ18615.1 - 1.7e-05 24.5 0.1 8.7e-05 22.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 OAJ18615.1 - 0.0002 21.3 0.0 0.00069 19.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 OAJ18615.1 - 0.00069 19.6 0.1 0.0025 17.8 0.0 1.8 2 1 0 2 2 1 1 AAA ATPase domain DUF815 PF05673.8 OAJ18615.1 - 0.002 17.0 0.0 0.0035 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 OAJ18615.1 - 0.0029 18.4 0.5 0.0076 17.0 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 OAJ18615.1 - 0.0056 16.4 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 OAJ18615.1 - 0.0086 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAJ18615.1 - 0.0089 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 OAJ18615.1 - 0.0091 15.1 0.0 0.021 13.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 OAJ18615.1 - 0.0094 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 OAJ18615.1 - 0.02 14.9 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 OAJ18615.1 - 0.023 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 OAJ18615.1 - 0.038 13.6 0.0 0.084 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 OAJ18615.1 - 0.041 14.1 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 OAJ18615.1 - 0.048 12.8 0.1 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 OAJ18615.1 - 0.049 13.5 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 OAJ18615.1 - 0.06 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Arch_ATPase PF01637.13 OAJ18615.1 - 0.12 12.0 0.1 19 4.8 0.0 2.5 2 1 1 3 3 2 0 Archaeal ATPase Sigma54_activat PF00158.21 OAJ18615.1 - 0.12 11.8 0.0 0.31 10.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 OAJ18615.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Glutaredoxin PF00462.19 OAJ18616.1 - 1.2e-18 66.8 0.0 1.5e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 OAJ18616.1 - 0.00051 20.2 0.1 0.001 19.2 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.9 OAJ18616.1 - 0.00059 20.0 0.0 0.00078 19.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.1 OAJ18616.1 - 0.00086 19.4 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ18616.1 - 0.0021 17.9 0.0 0.003 17.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.1 OAJ18616.1 - 0.016 14.7 0.0 0.03 13.8 0.0 1.5 1 1 1 2 2 2 0 Thioredoxin TraF PF13728.1 OAJ18616.1 - 0.018 14.5 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Zn_ribbon_2 PF12674.2 OAJ18616.1 - 0.024 14.9 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative zinc ribbon domain Thioredoxin_7 PF13899.1 OAJ18616.1 - 0.03 14.3 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like DSBA PF01323.15 OAJ18616.1 - 0.058 12.9 0.1 0.29 10.6 0.1 1.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 OAJ18616.1 - 0.13 12.2 0.5 3.2 7.7 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin DUF1804 PF08822.6 OAJ18636.1 - 0.076 12.7 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) bZIP_1 PF00170.16 OAJ18637.1 - 3.7e-07 29.9 11.6 3.7e-07 29.9 8.0 3.5 2 1 2 4 4 4 3 bZIP transcription factor Hap4_Hap_bind PF10297.4 OAJ18637.1 - 7.8e-07 28.7 5.1 7.8e-07 28.7 3.5 2.8 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 V_ATPase_I PF01496.14 OAJ18637.1 - 0.64 7.7 4.5 0.92 7.2 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SNF2_N PF00176.18 OAJ18639.1 - 8e-71 238.2 2.0 1.5e-70 237.3 1.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 OAJ18639.1 - 1.7e-53 180.4 22.3 1.7e-53 180.4 15.4 3.0 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 OAJ18639.1 - 1.3e-12 47.4 0.0 3e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ18639.1 - 1.2e-05 25.2 0.1 0.00011 22.1 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit LIP PF03583.9 OAJ18640.1 - 5.1e-50 170.3 0.1 6.3e-50 169.9 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 OAJ18640.1 - 3.8e-07 29.9 0.1 9e-07 28.7 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ18640.1 - 5.4e-06 26.4 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ18640.1 - 1.5e-05 24.3 0.2 0.0031 16.7 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family Cutinase PF01083.17 OAJ18640.1 - 0.027 14.2 0.1 0.057 13.1 0.1 1.6 1 0 0 1 1 1 0 Cutinase PIP5K PF01504.13 OAJ18641.1 - 1.1e-63 214.6 0.0 2.5e-63 213.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 OAJ18641.1 - 7.3e-25 87.5 0.1 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 OAJ18641.1 - 9.5e-16 57.4 9.2 9.5e-16 57.4 6.3 1.8 2 0 0 2 2 2 1 FYVE zinc finger NRDE-2 PF08424.5 OAJ18641.1 - 0.33 9.7 0.0 0.76 8.5 0.0 1.5 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference APG5 PF04106.7 OAJ18671.1 - 6.7e-46 156.2 0.0 7.1e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 Autophagy protein Apg5 adh_short PF00106.20 OAJ18672.1 - 3.8e-12 46.4 0.0 5.9e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ18672.1 - 0.00051 19.8 0.0 0.00058 19.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase V-ATPase_H_N PF03224.9 OAJ18673.1 - 0.099 11.7 0.0 5.2 6.0 0.0 2.4 2 0 0 2 2 2 0 V-ATPase subunit H DUF1183 PF06682.7 OAJ18673.1 - 0.37 10.3 6.3 1.1 8.8 4.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) GRP PF07172.6 OAJ18673.1 - 6.3 7.3 13.2 0.28 11.6 5.0 1.9 2 0 0 2 2 2 0 Glycine rich protein family COPIIcoated_ERV PF07970.7 OAJ18674.1 - 2.1e-37 128.9 0.2 3.2e-37 128.3 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 OAJ18674.1 - 7.9e-23 80.2 0.0 1.3e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) NIF3 PF01784.13 OAJ18675.1 - 2.7e-56 190.8 0.0 3.4e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) RVT_1 PF00078.22 OAJ18676.1 - 7.4e-21 74.4 0.0 1.3e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ18676.1 - 9.4e-16 57.5 1.0 7.9e-15 54.5 0.1 2.8 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 OAJ18676.1 - 2e-14 54.0 0.1 5.9e-14 52.5 0.0 1.9 2 0 0 2 2 2 1 RNase H Reo_sigmaC PF04582.7 OAJ18676.1 - 3.2e-05 23.2 0.4 6.5e-05 22.2 0.3 1.4 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Exo_endo_phos PF03372.18 OAJ18676.1 - 0.0097 15.8 0.4 0.022 14.7 0.2 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 OAJ18676.1 - 0.05 13.9 0.1 0.16 12.2 0.1 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase PQ-loop PF04193.9 OAJ18678.1 - 5.2e-20 70.7 18.3 1.7e-10 40.2 0.3 3.3 3 0 0 3 3 3 2 PQ loop repeat Bindin PF02084.10 OAJ18678.1 - 0.0097 15.9 5.6 0.018 15.1 3.9 1.3 1 0 0 1 1 1 1 Bindin DUF21 PF01595.15 OAJ18678.1 - 0.019 14.2 0.2 0.019 14.2 0.1 3.9 4 1 1 5 5 5 0 Domain of unknown function DUF21 BSP_II PF05432.6 OAJ18678.1 - 0.024 13.9 3.0 0.037 13.3 2.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF3328 PF11807.3 OAJ18678.1 - 0.033 13.8 2.0 6.5 6.3 0.2 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3328) FAM176 PF14851.1 OAJ18678.1 - 0.49 10.0 2.9 2.4 7.8 1.1 2.2 2 0 0 2 2 2 0 FAM176 family YrhC PF14143.1 OAJ18678.1 - 3 7.8 4.7 4.1 7.4 0.4 2.9 2 0 0 2 2 2 0 YrhC-like protein Daxx PF03344.10 OAJ18678.1 - 4 5.8 7.5 5.5 5.3 5.2 1.1 1 0 0 1 1 1 0 Daxx Family Annexin PF00191.15 OAJ18679.1 - 2.8e-52 174.4 0.2 5.9e-13 48.5 0.1 4.2 4 0 0 4 4 4 4 Annexin Peptidase_M43 PF05572.8 OAJ18680.1 - 4.5e-18 65.3 0.1 6.7e-18 64.7 0.1 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 OAJ18680.1 - 0.001 19.0 0.9 0.0017 18.3 0.6 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 OAJ18680.1 - 0.0045 17.4 0.1 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 OAJ18680.1 - 0.0054 16.4 0.1 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M7 PF02031.11 OAJ18680.1 - 0.039 13.6 1.2 0.059 13.0 0.3 1.8 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_2 PF13574.1 OAJ18680.1 - 0.041 13.9 3.5 0.11 12.6 2.3 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 OAJ18680.1 - 0.13 11.7 0.9 0.22 11.0 0.6 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like LIN37 PF15306.1 OAJ18681.1 - 0.013 15.4 4.6 0.013 15.4 3.2 2.2 2 0 0 2 2 2 0 LIN37 NDK PF00334.14 OAJ18682.1 - 0.00011 21.9 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NDK PF00334.14 OAJ18715.1 - 2.4e-29 101.8 0.0 2.9e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Tcf25 PF04910.9 OAJ18716.1 - 1.1e-77 261.4 0.0 1.5e-77 260.9 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 XPC-binding PF09280.6 OAJ18716.1 - 0.024 14.0 1.0 1.2 8.6 0.0 2.7 2 0 0 2 2 2 0 XPC-binding domain TPR_12 PF13424.1 OAJ18716.1 - 0.048 13.5 0.8 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat 6PF2K PF01591.13 OAJ18717.1 - 2.6e-69 232.7 0.0 3.7e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 OAJ18717.1 - 8.1e-31 107.2 0.0 1.7e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 OAJ18717.1 - 2.9e-09 36.9 0.0 6.2e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ18717.1 - 0.00029 21.6 0.0 0.0034 18.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain GBP PF02263.14 OAJ18717.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain NO_synthase PF02898.10 OAJ18717.1 - 0.16 10.6 0.0 0.27 9.8 0.0 1.3 1 0 0 1 1 1 0 Nitric oxide synthase, oxygenase domain KTI12 PF08433.5 OAJ18717.1 - 0.19 10.9 0.0 0.57 9.3 0.0 1.8 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Spt20 PF12090.3 OAJ18718.1 - 1.2e-34 119.2 0.0 1.2e-34 119.2 0.0 5.6 4 2 0 4 4 4 2 Spt20 family AAA_23 PF13476.1 OAJ18718.1 - 0.013 15.7 10.0 0.013 15.7 6.9 3.3 3 0 0 3 3 3 0 AAA domain TFIIF_alpha PF05793.7 OAJ18718.1 - 1.2 7.4 60.1 0.0069 14.8 30.3 2.5 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AAA PF00004.24 OAJ18719.1 - 1.1e-13 51.4 0.0 2.4e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 OAJ18719.1 - 4.7e-08 32.1 0.0 0.0029 16.3 0.0 2.9 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 OAJ18719.1 - 2.5e-05 24.2 0.0 4.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ18719.1 - 2.8e-05 23.7 0.0 0.0001 21.9 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 OAJ18719.1 - 7.8e-05 21.8 0.0 0.00015 20.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 OAJ18719.1 - 0.00017 21.5 0.1 0.038 13.9 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 OAJ18719.1 - 0.0002 21.3 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 OAJ18719.1 - 0.00045 21.0 0.6 0.0013 19.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 OAJ18719.1 - 0.004 17.3 0.0 0.014 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 OAJ18719.1 - 0.015 15.2 0.9 0.03 14.2 0.0 2.0 3 0 0 3 3 1 0 AAA domain AAA_33 PF13671.1 OAJ18719.1 - 0.022 14.6 0.1 0.081 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 OAJ18719.1 - 0.03 14.0 0.1 0.13 11.9 0.0 2.0 1 1 1 2 2 2 0 NTPase NACHT PF05729.7 OAJ18719.1 - 0.043 13.4 0.0 0.097 12.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 OAJ18719.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 OAJ18719.1 - 0.065 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 OAJ18719.1 - 0.07 13.4 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 OAJ18719.1 - 0.077 12.4 0.0 0.26 10.6 0.0 1.8 1 1 1 2 2 2 0 AAA-like domain Membr_traf_MHD PF10540.4 OAJ18719.1 - 0.13 12.0 0.0 0.35 10.6 0.0 1.7 2 0 0 2 2 1 0 Munc13 (mammalian uncoordinated) homology domain KaiC PF06745.8 OAJ18719.1 - 0.26 10.3 0.0 0.55 9.2 0.0 1.4 1 0 0 1 1 1 0 KaiC Mito_carr PF00153.22 OAJ18720.1 - 1.2e-27 95.3 8.1 5e-14 51.7 0.0 3.3 2 1 0 3 3 3 3 Mitochondrial carrier protein Copper-fist PF00649.13 OAJ18721.1 - 1.4e-14 52.9 0.3 3.4e-14 51.7 0.2 1.7 1 0 0 1 1 1 1 Copper fist DNA binding domain Apq12 PF12716.2 OAJ18722.1 - 0.75 9.5 10.6 0.082 12.6 2.6 2.1 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis AAA_13 PF13166.1 OAJ18724.1 - 0.12 10.8 9.9 0.15 10.4 6.9 1.1 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 OAJ18724.1 - 0.12 11.5 20.0 0.062 12.4 12.1 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 OAJ18724.1 - 2 7.4 14.7 3.1 6.7 10.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 OAJ18724.1 - 4.9 6.0 15.4 2 7.2 7.5 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF465 PF04325.8 OAJ18724.1 - 5.7 6.7 13.6 0.094 12.4 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Vps53_N PF04100.7 OAJ18726.1 - 5.3e-85 285.5 2.6 8.6e-85 284.8 1.8 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 OAJ18726.1 - 0.0045 15.9 6.1 0.0088 14.9 4.2 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 OAJ18726.1 - 0.034 13.8 3.3 0.1 12.3 2.3 1.8 1 0 0 1 1 1 0 Exocyst complex component Sec5 PGC7_Stella PF15549.1 OAJ18726.1 - 1 9.3 4.9 0.48 10.4 0.1 2.3 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain Baculo_PEP_C PF04513.7 OAJ18726.1 - 3.8 7.3 9.4 10 5.9 5.2 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_14 PF13428.1 OAJ18727.1 - 8.8e-19 66.3 24.2 0.0095 16.4 0.0 10.9 7 2 5 12 12 10 7 Tetratricopeptide repeat HAT PF02184.11 OAJ18727.1 - 4.3e-17 61.5 56.7 2.7e-09 36.6 0.4 14.1 16 0 0 16 16 15 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 OAJ18727.1 - 2.5e-12 46.9 1.4 0.037 14.3 0.0 6.5 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ18727.1 - 3.7e-09 36.0 2.8 0.35 10.5 0.0 6.4 4 2 3 7 7 7 3 TPR repeat TPR_12 PF13424.1 OAJ18727.1 - 4e-08 33.0 4.6 4.7 7.2 0.1 5.7 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ18727.1 - 4.7e-08 32.3 4.3 3.3 7.8 0.0 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ18727.1 - 8.9e-07 29.4 18.7 0.00044 20.8 0.1 6.8 4 2 5 10 10 9 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ18727.1 - 0.00091 18.8 0.0 2.7 7.9 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ18727.1 - 0.0025 17.3 1.0 73 3.2 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ18727.1 - 0.011 15.8 0.0 1.7 9.0 0.0 3.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ18727.1 - 0.041 13.6 17.0 3.8 7.5 0.0 8.2 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ18727.1 - 0.083 13.3 5.2 85 3.9 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 OAJ18727.1 - 0.26 11.0 11.9 0.21 11.3 0.2 4.7 4 1 1 5 5 5 0 U3 small nucleolar RNA-associated protein 6 Nucleoplasmin PF03066.10 OAJ18727.1 - 3.6 7.0 13.5 0.99 8.9 1.5 2.8 3 0 0 3 3 3 0 Nucleoplasmin DUF4611 PF15387.1 OAJ18727.1 - 8.1 6.6 10.7 15 5.8 2.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Acetyltransf_1 PF00583.19 OAJ18728.1 - 0.0016 18.3 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GTP_EFTU PF00009.22 OAJ18754.1 - 1.2e-30 106.3 0.0 6e-30 104.0 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 OAJ18754.1 - 2e-15 56.6 0.1 6.3e-15 54.9 0.0 1.9 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 OAJ18754.1 - 1.4e-10 41.1 10.5 1.1e-09 38.2 0.2 3.8 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAJ18754.1 - 1.1e-06 28.5 0.0 3.6e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 OAJ18754.1 - 0.0091 16.1 0.1 0.036 14.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain PapB PF03333.8 OAJ18754.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein AAA_16 PF13191.1 OAJ18754.1 - 0.38 10.7 0.0 0.38 10.7 0.0 3.1 2 0 0 2 2 2 0 AAA ATPase domain Trm112p PF03966.11 OAJ18755.1 - 6.9e-17 61.5 0.1 1e-16 61.0 0.1 1.3 1 0 0 1 1 1 1 Trm112p-like protein zinc_ribbon_5 PF13719.1 OAJ18755.1 - 0.11 12.1 0.1 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain HypA PF01155.14 OAJ18755.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.7 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-DHHC PF01529.15 OAJ18756.1 - 1.3e-20 73.5 1.8 6.1e-19 68.0 0.0 2.2 1 1 0 2 2 2 1 DHHC palmitoyltransferase DUF1180 PF06679.7 OAJ18756.1 - 0.015 15.1 0.1 0.032 14.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4583 PF15190.1 OAJ18756.1 - 0.34 10.5 4.0 0.25 10.9 0.8 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4583) Abhydrolase_3 PF07859.8 OAJ18758.1 - 1.1e-29 103.5 0.0 2.2e-29 102.5 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAJ18758.1 - 0.00013 20.7 0.0 0.00022 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 OAJ18758.1 - 0.00021 21.0 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ18758.1 - 0.16 11.1 0.0 4.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family GYF PF02213.11 OAJ18759.1 - 3.7e-18 64.8 0.7 8e-18 63.7 0.5 1.5 1 0 0 1 1 1 1 GYF domain Xpo1 PF08389.7 OAJ18760.1 - 1.4e-26 93.2 0.2 4.7e-24 84.9 0.0 3.6 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 OAJ18760.1 - 1.4e-06 28.1 0.3 5.2e-06 26.2 0.1 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain ParcG PF10274.4 OAJ18760.1 - 0.0014 18.5 0.1 0.34 10.7 0.0 3.1 2 1 1 3 3 3 1 Parkin co-regulated protein DUF2489 PF10675.4 OAJ18760.1 - 0.048 13.3 0.1 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) HEAT PF02985.17 OAJ18760.1 - 0.6 10.3 4.2 1.4 9.1 0.1 3.8 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 OAJ18760.1 - 2.3 8.8 15.9 2 9.0 0.1 6.3 4 2 2 6 6 6 0 HEAT-like repeat Indigoidine_A PF04227.7 OAJ18761.1 - 4.3e-107 357.6 1.1 4.3e-107 357.6 0.8 1.6 2 0 0 2 2 2 1 Indigoidine synthase A like protein PfkB PF00294.19 OAJ18761.1 - 2.2e-17 63.1 1.3 1.2e-09 37.7 0.1 2.4 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Myb_DNA-binding PF00249.26 OAJ18762.1 - 7e-19 67.6 4.7 4.5e-14 52.2 1.4 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ18762.1 - 2.4e-13 49.9 4.9 2.7e-12 46.6 1.8 4.1 2 1 2 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ18762.1 - 2.6e-05 24.2 8.7 0.0057 16.7 0.0 3.4 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 OAJ18762.1 - 0.045 13.9 0.8 0.045 13.9 0.6 2.6 3 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DNA_ligase_A_M PF01068.16 OAJ18763.1 - 1.8e-37 128.7 0.0 1.3e-25 89.9 0.0 4.0 3 1 0 3 3 3 3 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 OAJ18763.1 - 4.8e-35 120.9 0.1 1.2e-34 119.7 0.0 1.7 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 OAJ18763.1 - 1e-17 64.3 0.1 4.9e-17 62.1 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DUF2433 PF10360.4 OAJ18764.1 - 5.2e-41 140.0 0.1 1e-40 139.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) PAT1 PF09770.4 OAJ18764.1 - 1 7.5 4.6 1.5 7.0 3.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 OAJ18764.1 - 1.7 8.0 30.7 0.23 10.8 11.3 2.3 2 0 0 2 2 2 0 Vta1 like MPC PF03650.8 OAJ18790.1 - 0.22 11.4 1.2 0.24 11.3 0.2 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0041) DUF155 PF02582.9 OAJ18791.1 - 8e-52 175.6 0.0 1.2e-51 175.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 VHS PF00790.14 OAJ18792.1 - 1.7e-35 121.7 1.7 2.3e-35 121.2 0.0 2.0 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 OAJ18792.1 - 2.7e-16 59.2 9.3 5e-16 58.3 6.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 OAJ18792.1 - 5.2e-05 22.4 6.7 0.0044 16.4 0.6 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.11 OAJ18792.1 - 9.7e-05 22.2 2.8 0.0002 21.2 2.0 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger DUF3602 PF12223.3 OAJ18792.1 - 0.00016 22.0 1.2 0.00016 22.0 0.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3602) zf-RING_5 PF14634.1 OAJ18792.1 - 1.2 8.9 11.4 1.9 8.2 7.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DnaJ PF00226.26 OAJ18793.1 - 3.3e-24 84.3 0.4 5.6e-24 83.6 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 OAJ18793.1 - 4.9e-14 52.4 0.0 9.4e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Ashwin PF15323.1 OAJ18793.1 - 0.034 14.1 2.7 0.048 13.6 1.9 1.2 1 0 0 1 1 1 0 Developmental protein SR-25 PF10500.4 OAJ18793.1 - 0.059 12.8 6.0 0.093 12.1 4.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.6 OAJ18794.1 - 0.45 8.3 3.0 0.65 7.7 2.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cpn60_TCP1 PF00118.19 OAJ18795.1 - 1.5e-149 498.7 1.9 1.7e-149 498.5 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family COLFI PF01410.13 OAJ18796.1 - 0.046 13.1 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain Tmemb_14 PF03647.8 OAJ18797.1 - 6.3e-16 58.5 9.8 8e-16 58.2 6.8 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C Glyco_hydro_2 PF00703.16 OAJ18798.1 - 1.5e-08 35.0 0.1 3.2e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 OAJ18798.1 - 0.039 12.8 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF4217 PF13959.1 OAJ18798.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) Shisa PF13908.1 OAJ18799.1 - 0.11 12.6 0.0 0.11 12.6 0.0 2.8 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator AMP-binding PF00501.23 OAJ18800.1 - 4.8e-50 170.1 0.0 8.6e-50 169.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.19 OAJ18800.1 - 7.5e-12 44.1 0.7 0.00011 21.4 0.0 6.6 7 0 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.20 OAJ18800.1 - 3.9e-11 43.0 0.6 8.1e-11 42.0 0.4 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 OAJ18800.1 - 5e-09 36.9 2.3 7.3e-06 26.8 0.1 3.3 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.1 OAJ18800.1 - 0.0049 16.3 7.1 3.4 7.3 0.2 5.2 5 1 1 6 6 6 2 Hexapeptide repeat of succinyl-transferase GH3 PF03321.8 OAJ18800.1 - 0.48 8.8 0.1 14 4.0 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter CBFB_NFYA PF02045.10 OAJ18833.1 - 4.9e-20 71.8 16.3 1.6e-11 44.5 3.6 2.9 2 2 0 2 2 2 2 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B GHMP_kinases_C PF08544.8 OAJ18833.1 - 0.00022 21.3 1.7 0.58 10.3 0.1 2.4 2 0 0 2 2 2 2 GHMP kinases C terminal ADP_ribosyl_GH PF03747.9 OAJ18833.1 - 0.046 13.4 5.6 0.066 12.9 3.9 1.3 1 1 0 1 1 1 0 ADP-ribosylglycohydrolase Atrophin-1 PF03154.10 OAJ18833.1 - 0.048 11.8 4.3 0.067 11.3 3.0 1.2 1 0 0 1 1 1 0 Atrophin-1 family DUF2404 PF10296.4 OAJ18834.1 - 0.00028 20.9 0.0 0.00056 19.9 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PHD PF00628.24 OAJ18835.1 - 1.4e-05 24.6 8.5 1.4e-05 24.6 5.9 2.4 2 1 0 2 2 2 1 PHD-finger FANCL_C PF11793.3 OAJ18835.1 - 0.0072 16.2 1.2 0.02 14.8 0.9 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain C1_1 PF00130.17 OAJ18835.1 - 0.043 13.5 0.3 0.043 13.5 0.2 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 OAJ18835.1 - 1.7 8.8 9.0 0.17 12.0 1.9 2.6 2 1 0 2 2 2 0 PHD-like zinc-binding domain Peptidase_S10 PF00450.17 OAJ18837.1 - 1.9e-98 330.3 0.0 2.5e-98 329.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF418 PF04235.7 OAJ18838.1 - 0.042 13.5 0.3 0.042 13.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF418) DUF212 PF02681.9 OAJ18838.1 - 0.14 11.8 1.9 0.16 11.6 0.1 2.0 2 0 0 2 2 2 0 Divergent PAP2 family UCH PF00443.24 OAJ18841.1 - 0.15 11.1 0.1 0.15 11.1 0.0 1.2 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase ADH_zinc_N_2 PF13602.1 OAJ18842.1 - 6.3e-17 62.6 0.4 6.9e-16 59.3 0.0 2.4 1 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 OAJ18842.1 - 2.2e-14 53.0 0.4 4.6e-14 52.0 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ18842.1 - 6.3e-13 48.4 0.3 3.4e-09 36.4 0.0 3.4 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain Abhydrolase_6 PF12697.2 OAJ18843.1 - 2.9e-08 33.8 0.5 2.9e-08 33.8 0.4 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ18843.1 - 0.13 11.9 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PIN_4 PF13638.1 OAJ18844.1 - 7.9e-06 26.0 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 PIN domain UCH PF00443.24 OAJ18845.1 - 0.016 14.3 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase FAD_binding_3 PF01494.14 OAJ18880.1 - 1.5e-16 60.3 0.0 3.4e-16 59.2 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAJ18880.1 - 0.0087 16.0 0.1 0.018 15.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 OAJ18880.1 - 0.0092 14.8 0.0 0.034 12.9 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.22 OAJ18880.1 - 0.01 16.2 0.2 0.074 13.4 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ18880.1 - 0.011 14.6 0.1 0.85 8.4 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.11 OAJ18880.1 - 0.022 14.2 0.1 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 OAJ18880.1 - 0.17 11.7 0.2 1.3 8.8 0.1 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 OAJ18881.1 - 4.3e-46 157.4 1.6 5e-44 150.6 0.3 2.7 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ18881.1 - 2.2e-30 105.8 0.0 3.6e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 OAJ18881.1 - 1.8e-06 27.8 0.1 4.9e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAJ18881.1 - 2.2e-06 26.7 0.3 0.00048 19.0 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAJ18881.1 - 1.4e-05 24.2 0.3 2.6e-05 23.3 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAJ18881.1 - 6.4e-05 22.0 0.1 9.9e-05 21.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 OAJ18881.1 - 0.00063 19.6 0.2 0.0019 18.0 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAJ18881.1 - 0.00069 18.7 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 OAJ18881.1 - 0.013 14.6 1.3 0.026 13.6 0.1 1.9 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 OAJ18881.1 - 0.022 14.5 0.1 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 OAJ18881.1 - 0.039 14.0 0.1 0.082 12.9 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 OAJ18881.1 - 0.075 13.0 0.0 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.22 OAJ18881.1 - 0.08 13.3 0.1 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ18881.1 - 0.081 11.3 0.0 0.15 10.5 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Ribosomal_S25 PF03297.10 OAJ18882.1 - 3.6e-40 136.2 2.6 4.4e-40 135.9 1.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 OAJ18882.1 - 0.023 14.0 0.1 0.038 13.3 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.17 OAJ18882.1 - 0.04 13.6 0.2 0.077 12.7 0.1 1.5 2 0 0 2 2 2 0 MarR family CoA_trans PF01144.18 OAJ18882.1 - 0.094 11.8 0.0 0.21 10.7 0.0 1.5 1 1 1 2 2 2 0 Coenzyme A transferase MTS PF05175.9 OAJ18882.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain S10_plectin PF03501.10 OAJ18883.1 - 3.7e-39 132.4 0.1 4.6e-39 132.1 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain HTH_45 PF14947.1 OAJ18883.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DUF4404 PF14357.1 OAJ18883.1 - 0.14 12.6 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Sulfotransfer_3 PF13469.1 OAJ18884.1 - 7.2e-05 23.7 2.1 0.00018 22.4 1.4 1.6 1 1 0 1 1 1 1 Sulfotransferase family XhlA PF10779.4 OAJ18884.1 - 0.048 13.5 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Haemolysin XhlA F_bP_aldolase PF01116.15 OAJ18885.1 - 1.1e-82 277.4 0.1 5.7e-54 183.1 0.0 2.0 1 1 1 2 2 2 2 Fructose-bisphosphate aldolase class-II DER1 PF04511.10 OAJ18886.1 - 3.4e-28 98.4 0.8 4.5e-28 98.1 0.5 1.1 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 OAJ18886.1 - 0.051 13.6 3.2 0.083 12.9 2.2 1.4 1 0 0 1 1 1 0 Rhomboid family Nup88 PF10168.4 OAJ18887.1 - 5.2e-08 31.2 0.9 0.19 9.5 0.0 4.2 4 0 0 4 4 4 3 Nuclear pore component SlyX PF04102.7 OAJ18887.1 - 0.51 10.7 10.5 2.2 8.6 0.3 3.7 4 0 0 4 4 4 0 SlyX AATF-Che1 PF13339.1 OAJ18887.1 - 2 8.5 5.5 12 6.0 0.2 2.8 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor EAP30 PF04157.11 OAJ18887.1 - 6.3 5.8 9.7 1.8 7.6 0.1 2.8 3 0 0 3 3 3 0 EAP30/Vps36 family V-ATPase_C PF03223.10 OAJ18889.1 - 1.2e-120 402.8 2.9 1.3e-120 402.7 2.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Virulence_fact PF13769.1 OAJ18889.1 - 0.39 10.6 2.8 1.1 9.2 0.1 2.7 2 1 1 3 3 3 0 Virulence factor DUF3818 PF12825.2 OAJ18890.1 - 4.9e-40 137.2 0.0 8.1e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 OAJ18890.1 - 2.2e-19 69.3 0.0 4e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 PX-associated zf-CCCH PF00642.19 OAJ18891.1 - 6.5e-09 35.2 2.5 1.2e-08 34.4 1.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 OAJ18891.1 - 1.4e-07 31.0 5.3 2.2e-07 30.4 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ18891.1 - 1.4e-07 31.4 9.8 2.4e-07 30.6 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ18891.1 - 2.3e-06 27.3 7.0 3.6e-06 26.6 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAJ18891.1 - 4.8e-06 26.1 8.6 7.8e-06 25.5 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 OAJ18891.1 - 2.5e-05 23.8 8.5 4.3e-05 23.0 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAJ18891.1 - 7.5e-05 22.5 7.8 0.00015 21.5 5.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 OAJ18891.1 - 0.00031 20.3 5.6 0.00078 19.1 3.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 OAJ18891.1 - 0.013 14.9 3.0 0.025 14.0 2.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cript PF10235.4 OAJ18891.1 - 0.31 11.4 3.1 0.8 10.0 2.1 1.8 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT zf-rbx1 PF12678.2 OAJ18891.1 - 0.39 10.8 4.6 1.1 9.4 3.2 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger Aldedh PF00171.17 OAJ18892.1 - 8.8e-156 518.8 0.0 9.9e-156 518.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAJ18892.1 - 0.00019 20.3 0.1 0.00029 19.7 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Pkinase PF00069.20 OAJ18922.1 - 5.2e-68 229.0 0.0 8.5e-68 228.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ18922.1 - 1.6e-29 102.7 0.0 2.6e-28 98.8 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 OAJ18922.1 - 0.00014 21.2 0.6 0.00025 20.4 0.4 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 OAJ18922.1 - 0.0002 20.3 0.7 0.52 9.2 0.0 3.1 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 OAJ18922.1 - 0.0019 17.9 3.7 0.29 10.8 0.1 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 OAJ18922.1 - 0.082 11.6 0.1 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Peptidase_S64 PF08192.6 OAJ18922.1 - 1.1 7.4 8.5 1.7 6.9 5.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 WD40 PF00400.27 OAJ18924.1 - 2.7e-12 46.0 4.3 0.094 12.6 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat F-box-like PF12937.2 OAJ18924.1 - 1.2e-10 40.9 0.0 2.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ18924.1 - 0.00014 21.3 0.0 0.00031 20.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain UIM PF02809.15 OAJ18924.1 - 0.0056 16.1 7.8 0.088 12.4 0.6 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif Ribosomal_L29e PF01779.12 OAJ18926.1 - 4.2e-06 26.5 13.6 4.2e-06 26.5 9.5 1.5 2 0 0 2 2 2 1 Ribosomal L29e protein family DUF3008 PF11450.3 OAJ18926.1 - 0.13 12.4 4.5 0.22 11.6 3.1 1.5 1 1 0 1 1 1 0 Protein of unknwon function (DUF3008) Ribosomal_L11 PF00298.14 OAJ18926.1 - 0.17 12.0 0.8 0.21 11.7 0.5 1.1 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain Noc2 PF03715.8 OAJ18927.1 - 7.8e-101 336.8 0.1 1.8e-100 335.7 0.0 1.6 2 0 0 2 2 2 1 Noc2p family BUD22 PF09073.5 OAJ18927.1 - 5.6 5.9 27.9 12 4.8 19.3 1.5 1 0 0 1 1 1 0 BUD22 RrnaAD PF00398.15 OAJ18928.1 - 1.3e-55 188.2 0.0 1.8e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 OAJ18928.1 - 4.3e-10 39.6 0.0 6.9e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ18928.1 - 9.4e-06 25.1 0.0 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 OAJ18928.1 - 5e-05 23.8 0.0 9.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAJ18928.1 - 8.5e-05 21.7 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 OAJ18928.1 - 0.00013 21.5 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 OAJ18928.1 - 0.00023 20.6 0.0 0.00046 19.6 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.14 OAJ18928.1 - 0.00039 20.0 0.0 0.00062 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 OAJ18928.1 - 0.00046 19.8 0.0 0.001 18.6 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 OAJ18928.1 - 0.0015 19.0 0.0 0.0026 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ18928.1 - 0.003 17.3 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ18928.1 - 0.06 12.4 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 OAJ18928.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.1 OAJ18928.1 - 0.081 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 OAJ18928.1 - 0.14 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase zf-C2H2_4 PF13894.1 OAJ18929.1 - 9.8e-10 38.0 7.9 0.00024 21.2 2.6 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 OAJ18929.1 - 1.9e-09 37.2 7.6 0.00037 20.6 3.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAJ18929.1 - 2.8e-09 36.8 9.8 1.6e-07 31.2 1.0 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 OAJ18929.1 - 0.00032 20.7 5.5 0.0044 17.1 0.5 2.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 OAJ18929.1 - 0.015 15.6 2.2 0.022 15.1 1.5 1.3 1 0 0 1 1 1 0 TRAF-type zinc finger zf-met PF12874.2 OAJ18929.1 - 0.017 15.3 1.9 0.03 14.5 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CUE PF02845.11 OAJ18930.1 - 1.7e-09 36.9 0.0 3.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain COX6B PF02297.12 OAJ18962.1 - 5e-23 80.8 0.2 6.3e-23 80.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb SR-25 PF10500.4 OAJ18962.1 - 1.6 8.1 6.4 0.44 9.9 1.2 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Glyco_hydro_9 PF00759.14 OAJ18963.1 - 2.1e-85 287.2 3.2 3.9e-50 171.0 0.4 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 9 CENP-F_leu_zip PF10473.4 OAJ18964.1 - 0.0015 18.4 15.8 0.0015 18.4 11.0 3.8 3 1 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DDE_Tnp_4 PF13359.1 OAJ18965.1 - 7.4e-22 77.6 0.0 9.7e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.1 OAJ18965.1 - 0.00063 19.8 0.1 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.16 OAJ18965.1 - 0.0021 17.6 0.3 0.0088 15.6 0.2 1.8 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.9 OAJ18965.1 - 0.0075 15.6 0.0 0.0082 15.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_3 PF12776.2 OAJ18966.1 - 6.7e-18 65.1 2.0 1.4e-11 44.8 0.1 2.4 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ18966.1 - 3.4e-10 39.9 6.1 4.2e-05 23.6 0.5 2.6 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain PSK PF06404.7 OAJ18966.1 - 0.008 16.9 0.1 8 7.3 0.0 2.9 3 0 0 3 3 3 2 Phytosulfokine precursor protein (PSK) PilJ PF13675.1 OAJ18966.1 - 0.011 16.0 2.0 1.9 8.8 0.1 2.9 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term HHH_2 PF12826.2 OAJ18966.1 - 0.018 14.9 0.2 9.6 6.1 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif TMEM247 PF15444.1 OAJ18966.1 - 0.19 11.5 0.2 0.43 10.3 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 247 adh_short PF00106.20 OAJ19000.1 - 2.5e-09 37.2 0.7 3.9e-07 30.1 1.0 2.8 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 OAJ19000.1 - 9.9e-08 32.1 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAJ19000.1 - 2.1e-07 30.6 0.0 2.8e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 OAJ19000.1 - 0.0063 15.6 0.0 0.0087 15.2 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) MoCF_biosynth PF00994.19 OAJ19001.1 - 2.1e-34 117.9 0.0 3.6e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain ELO PF01151.13 OAJ19002.1 - 1.7e-57 194.5 7.3 2.2e-57 194.2 5.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family MaoC_dehydratas PF01575.14 OAJ19003.1 - 3.2e-23 81.4 0.0 6.4e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 OAJ19003.1 - 1.1e-08 34.9 0.0 2.7e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Sigma_reg_N PF13800.1 OAJ19004.1 - 0.83 9.7 3.0 3.8 7.6 0.0 2.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF1072 PF06380.6 OAJ19004.1 - 2 8.1 6.6 2.1 8.0 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Abhydrolase_5 PF12695.2 OAJ19005.1 - 0.0015 18.2 0.4 0.013 15.2 0.0 2.7 2 1 1 3 3 3 1 Alpha/beta hydrolase family Ribosomal_S4 PF00163.14 OAJ19006.1 - 3e-27 94.8 0.9 6.3e-27 93.7 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 OAJ19006.1 - 5.2e-12 44.9 1.5 5.2e-12 44.9 1.0 2.7 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 OAJ19007.1 - 1.7e-36 124.0 2.2 1.7e-36 124.0 0.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e TRAP-gamma PF07074.7 OAJ19007.1 - 0.051 13.1 0.2 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF3708 PF12501.3 OAJ19007.1 - 0.058 13.2 0.0 0.066 13.0 0.0 1.1 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Phi_1 PF04674.7 OAJ19008.1 - 0.15 11.2 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region CENP-F_leu_zip PF10473.4 OAJ19008.1 - 0.22 11.3 13.3 1.6 8.5 5.6 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 OAJ19008.1 - 8.8 3.5 23.3 0.15 9.3 11.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Coprogen_oxidas PF01218.13 OAJ19009.1 - 1.4e-110 368.5 0.7 1.5e-69 233.8 0.0 3.2 2 1 0 2 2 2 2 Coproporphyrinogen III oxidase Vfa1 PF08432.5 OAJ19010.1 - 8.9e-32 110.5 0.7 3.1e-31 108.7 0.5 1.7 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 PV-1 PF06637.6 OAJ19010.1 - 0.12 10.8 1.7 0.2 10.2 1.2 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) FKBP_N PF01346.13 OAJ19010.1 - 0.15 12.0 3.3 0.27 11.3 2.3 1.3 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Phage_Gp23 PF10669.4 OAJ19010.1 - 1.7 8.7 4.2 2.7 8.0 2.9 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Mtr2 PF10429.4 OAJ19011.1 - 0.064 13.0 0.0 0.82 9.4 0.0 2.2 1 1 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Saccharop_dh PF03435.13 OAJ19012.1 - 1.6e-23 83.3 0.0 2.3e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 OAJ19012.1 - 1.9e-07 30.7 0.0 3.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ19012.1 - 1.2e-06 28.7 0.0 3.1e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 OAJ19012.1 - 1.5e-05 25.0 0.3 2.7e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 OAJ19012.1 - 0.00016 21.0 0.1 0.00027 20.2 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 OAJ19012.1 - 0.00069 18.3 0.0 0.0014 17.4 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 OAJ19012.1 - 0.0022 17.7 0.1 0.0038 16.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 OAJ19012.1 - 0.0031 17.7 0.0 0.0055 17.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 OAJ19012.1 - 0.0049 16.9 0.0 0.0091 16.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 OAJ19012.1 - 0.024 13.5 0.3 0.13 11.1 0.1 2.3 2 1 0 2 2 2 0 Male sterility protein DapB_N PF01113.15 OAJ19012.1 - 0.097 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Phospho_p8 PF10195.4 OAJ19013.1 - 0.77 9.6 12.8 8.9 6.2 8.9 2.1 1 1 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 DUF1510 PF07423.6 OAJ19013.1 - 2.1 7.6 12.8 2.3 7.5 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Dsh_C PF12316.3 OAJ19013.1 - 2.9 7.9 13.1 3.1 7.8 9.1 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Gag_spuma PF03276.9 OAJ19013.1 - 3.9 5.6 9.9 4.1 5.6 6.9 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DDHD PF02862.12 OAJ19013.1 - 6.5 6.4 10.6 6.6 6.4 7.3 1.0 1 0 0 1 1 1 0 DDHD domain DUF566 PF04484.7 OAJ19013.1 - 6.6 6.1 11.3 6.8 6.0 7.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) POX PF07526.6 OAJ19013.1 - 7.7 6.7 10.0 9.2 6.4 6.9 1.1 1 0 0 1 1 1 0 Associated with HOX YqfQ PF14181.1 OAJ19013.1 - 8.6 6.3 11.8 9.8 6.1 8.2 1.2 1 0 0 1 1 1 0 YqfQ-like protein Sec62 PF03839.11 OAJ19013.1 - 8.9 5.6 7.4 9.7 5.5 5.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3408 PF11888.3 OAJ19013.1 - 9.2 6.2 10.2 11 6.0 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) FLO_LFY PF01698.11 OAJ19013.1 - 9.3 4.9 8.8 9.7 4.9 6.1 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein TRAPPC-Trs85 PF12739.2 OAJ19014.1 - 7.3e-94 314.7 0.2 1.1e-93 314.2 0.1 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit CARDB PF07705.6 OAJ19014.1 - 0.025 14.6 0.0 0.065 13.2 0.0 1.7 1 0 0 1 1 1 0 CARDB WD40 PF00400.27 OAJ19015.1 - 1.6e-15 56.2 13.2 0.00065 19.4 0.0 6.1 6 1 0 6 6 6 4 WD domain, G-beta repeat NUDIX PF00293.23 OAJ19049.1 - 2.8e-13 49.6 0.0 7e-13 48.3 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain NDK PF00334.14 OAJ19051.1 - 1.2e-50 170.7 0.0 1.6e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase SIS PF01380.17 OAJ19051.1 - 0.021 14.4 0.1 5.2 6.6 0.0 2.7 2 1 1 3 3 3 0 SIS domain Herpes_capsid PF06112.6 OAJ19051.1 - 0.11 12.5 3.3 0.17 11.9 2.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RCC1 PF00415.13 OAJ19052.1 - 1.8e-09 37.6 3.6 0.2 11.8 0.0 6.7 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ19052.1 - 0.0013 18.2 19.8 0.047 13.3 1.2 5.9 7 0 0 7 7 7 2 Regulator of chromosome condensation (RCC1) repeat DUF3000 PF11452.3 OAJ19052.1 - 0.061 12.5 1.4 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3000) TRAPPC9-Trs120 PF08626.6 OAJ19053.1 - 5.2e-89 299.0 0.0 4.5e-74 249.5 0.0 3.5 3 1 0 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit GAF_2 PF13185.1 OAJ19053.1 - 0.028 14.9 0.4 0.15 12.5 0.0 2.5 3 0 0 3 3 3 0 GAF domain His_Phos_2 PF00328.17 OAJ19055.1 - 9.2e-25 87.6 0.0 1.2e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 OAJ19055.1 - 0.033 14.2 0.0 0.088 12.8 0.0 1.8 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Tim17 PF02466.14 OAJ19056.1 - 1.2e-18 67.4 0.0 1.9e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family MRP-S33 PF08293.6 OAJ19057.1 - 5.3e-15 55.1 0.4 3.1e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal subunit S27 DUF3408 PF11888.3 OAJ19057.1 - 0.088 12.7 1.0 0.17 11.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Trs65 PF12735.2 OAJ19057.1 - 2.3 7.4 9.0 2.8 7.1 6.2 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 DUF2360 PF10152.4 OAJ19057.1 - 3 8.1 5.1 5.5 7.2 3.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Pkinase PF00069.20 OAJ19058.1 - 7.7e-72 241.5 0.0 8.7e-72 241.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ19058.1 - 1e-33 116.5 0.0 1.3e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ19058.1 - 0.00017 20.6 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ19058.1 - 0.0013 18.5 0.1 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ19058.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 OAJ19058.1 - 0.078 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CRAL_TRIO_2 PF13716.1 OAJ19058.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain ADH_zinc_N PF00107.21 OAJ19059.1 - 0.00096 18.6 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ19059.1 - 0.032 13.9 0.0 0.16 11.7 0.0 2.0 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 OAJ19059.1 - 0.094 13.6 0.0 0.43 11.4 0.0 2.1 2 1 1 3 3 3 0 Zinc-binding dehydrogenase Catalase PF00199.14 OAJ19060.1 - 9.9e-146 485.3 5.0 7.5e-131 436.3 1.3 2.0 2 0 0 2 2 2 2 Catalase Catalase-rel PF06628.7 OAJ19060.1 - 4.6e-14 52.0 0.1 1.6e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive Pkinase PF00069.20 OAJ19061.1 - 5.4e-73 245.3 0.0 6.1e-73 245.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ19061.1 - 4.4e-32 111.1 0.0 5.7e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ19061.1 - 7.6e-06 25.0 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ19061.1 - 0.0018 18.0 0.1 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ19061.1 - 0.012 14.4 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DivIVA PF05103.8 OAJ19087.1 - 0.0053 16.8 8.7 0.0096 15.9 6.0 1.4 1 0 0 1 1 1 1 DivIVA protein Transposase_22 PF02994.9 OAJ19087.1 - 0.012 14.1 2.4 0.015 13.7 1.6 1.2 1 0 0 1 1 1 0 L1 transposable element DUF3584 PF12128.3 OAJ19087.1 - 0.051 10.9 6.0 0.068 10.4 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RTBV_P46 PF06216.6 OAJ19087.1 - 0.07 11.9 0.1 0.097 11.4 0.0 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein APG6 PF04111.7 OAJ19087.1 - 0.2 10.6 4.5 0.27 10.2 3.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 OAJ19087.1 - 0.67 9.9 12.7 0.65 10.0 6.7 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Viral_P18 PF04521.8 OAJ19087.1 - 0.81 9.1 5.2 1.3 8.5 3.1 1.7 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DivIC PF04977.10 OAJ19087.1 - 1.4 8.4 12.1 0.92 9.0 1.7 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF4407 PF14362.1 OAJ19087.1 - 6.4 5.6 10.6 13 4.6 7.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3373 PF11853.3 OAJ19087.1 - 7.1 5.0 6.3 23 3.3 4.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) Dimer_Tnp_hAT PF05699.9 OAJ19088.1 - 3.8e-15 55.2 0.4 7.3e-15 54.3 0.3 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAJ19088.1 - 7.2e-07 29.1 0.1 3.3e-06 27.0 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4413) CCDC-167 PF15188.1 OAJ19088.1 - 0.51 10.3 4.7 1.5 8.7 0.5 2.8 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 Endonuc-FokI_C PF09254.6 OAJ19088.1 - 3.1 6.8 5.7 1.7 7.7 1.7 2.0 1 1 1 2 2 2 0 Restriction endonuclease FokI, C terminal Pkinase PF00069.20 OAJ19089.1 - 2.6e-37 128.4 0.0 3.6e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ19089.1 - 7.8e-19 67.7 0.0 1.2e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ19089.1 - 1.8e-08 33.6 0.0 2.9e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DAO PF01266.19 OAJ19115.1 - 1.1e-47 162.6 2.2 1.3e-47 162.4 1.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAJ19115.1 - 8e-07 29.3 0.1 0.004 17.5 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAJ19115.1 - 0.00024 21.0 1.2 0.00073 19.5 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 OAJ19115.1 - 0.0079 15.3 0.1 0.02 13.9 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 OAJ19115.1 - 0.014 15.2 0.1 0.06 13.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 OAJ19115.1 - 0.043 12.4 0.3 0.43 9.1 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Aminotran_3 PF00202.16 OAJ19116.1 - 3.2e-77 259.6 0.0 4.5e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III SUZ PF12752.2 OAJ19117.1 - 8.6e-14 51.8 0.0 8.6e-14 51.8 0.0 6.4 6 1 0 6 6 6 1 SUZ domain R3H PF01424.17 OAJ19117.1 - 4.8e-05 22.9 0.1 9.6e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 R3H domain UCH PF00443.24 OAJ19118.1 - 8.2e-40 136.6 0.0 1.2e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ19118.1 - 9.2e-12 44.9 0.0 3.1e-11 43.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Adaptin_N PF01602.15 OAJ19119.1 - 2e-100 336.6 10.9 3.3e-100 335.8 7.6 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 OAJ19119.1 - 2.1e-66 221.5 0.0 5.8e-66 220.1 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 OAJ19119.1 - 5.6e-62 207.5 0.1 1.4e-61 206.2 0.1 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 OAJ19119.1 - 3.7e-13 49.5 8.7 0.00032 20.9 0.0 5.6 3 1 1 5 5 5 3 HEAT repeats Cnd1 PF12717.2 OAJ19119.1 - 6.3e-10 39.1 7.9 0.0044 16.8 0.0 5.1 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 OAJ19119.1 - 5.1e-07 29.2 0.2 0.0068 16.4 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 OAJ19119.1 - 0.00015 22.0 0.5 1.5 9.3 0.0 4.3 3 0 0 3 3 3 2 HEAT-like repeat Cullin PF00888.17 OAJ19119.1 - 0.001 17.6 1.1 0.0034 15.9 0.2 2.0 2 0 0 2 2 2 1 Cullin family ParcG PF10274.4 OAJ19119.1 - 0.02 14.8 0.8 0.82 9.5 0.0 2.7 2 1 0 2 2 2 0 Parkin co-regulated protein DUF3810 PF12725.2 OAJ19119.1 - 0.075 11.9 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Arm PF00514.18 OAJ19119.1 - 0.86 9.5 3.9 81 3.2 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Dabb PF07876.7 OAJ19120.1 - 6.2e-15 55.4 0.1 7.1e-15 55.2 0.1 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Peptidase_S9 PF00326.16 OAJ19122.1 - 3.1e-48 163.8 0.1 4.8e-48 163.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAJ19122.1 - 1.9e-11 43.9 0.5 4.5e-11 42.7 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ19122.1 - 1e-08 35.3 4.5 3.4e-08 33.6 3.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 OAJ19122.1 - 0.0002 20.7 0.1 0.00038 19.7 0.1 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.15 OAJ19122.1 - 0.0011 18.4 0.4 0.0047 16.3 0.2 2.1 2 1 0 2 2 2 1 Putative esterase AXE1 PF05448.7 OAJ19122.1 - 0.01 14.3 0.4 0.88 8.0 0.0 2.3 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) PD40 PF07676.7 OAJ19122.1 - 0.087 12.5 0.8 0.52 10.0 0.0 2.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat COesterase PF00135.23 OAJ19122.1 - 0.68 8.5 3.6 0.89 8.1 1.5 1.8 2 1 0 2 2 2 0 Carboxylesterase family RNA12 PF10443.4 OAJ19124.1 - 7.5e-126 420.1 0.1 1.5e-125 419.1 0.0 1.4 1 1 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 OAJ19124.1 - 0.0042 16.8 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 Archaeal ATPase NAD_binding_8 PF13450.1 OAJ19125.1 - 9.1e-14 51.2 0.1 2.4e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 OAJ19125.1 - 6.5e-10 38.6 0.7 0.00011 21.4 0.0 3.0 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 OAJ19125.1 - 4.7e-06 26.8 0.1 0.00011 22.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ19125.1 - 1e-05 24.6 2.3 5.5e-05 22.2 0.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAJ19125.1 - 2.1e-05 24.3 0.1 0.0068 16.1 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 OAJ19125.1 - 9.2e-05 21.4 0.4 9.2e-05 21.4 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 OAJ19125.1 - 0.0076 16.6 0.3 0.016 15.6 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ19125.1 - 0.073 12.9 0.2 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 OAJ19125.1 - 0.21 11.1 0.1 0.35 10.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 OAJ19125.1 - 0.23 9.9 0.2 0.34 9.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 OAJ19125.1 - 0.66 8.7 1.6 0.99 8.1 1.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short PF00106.20 OAJ19126.1 - 4.4e-32 111.3 1.0 5.7e-32 110.9 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ19126.1 - 2.8e-15 56.4 0.3 3.7e-15 56.0 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ19126.1 - 2.9e-14 53.4 0.0 3.7e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAJ19126.1 - 0.00037 20.5 1.2 0.0043 17.0 0.8 2.2 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 OAJ19126.1 - 0.00049 19.8 0.4 0.0012 18.5 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 OAJ19126.1 - 0.00099 18.3 0.1 0.0024 17.0 0.1 1.7 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.5 OAJ19126.1 - 0.001 18.2 0.0 0.0014 17.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 OAJ19126.1 - 0.0022 17.4 0.1 0.0032 16.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 OAJ19126.1 - 0.0034 17.0 0.5 0.0062 16.1 0.3 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 OAJ19126.1 - 0.058 12.4 0.1 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain E2F_TDP PF02319.15 OAJ19126.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain ATP_bind_3 PF01171.15 OAJ19127.1 - 1.6e-35 122.2 0.0 3.6e-35 121.0 0.0 1.6 1 0 0 1 1 1 1 PP-loop family MMR_HSR1 PF01926.18 OAJ19127.1 - 6.1e-12 45.5 0.0 1.6e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 OAJ19127.1 - 0.00025 20.2 0.2 0.00076 18.6 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Asn_synthase PF00733.16 OAJ19127.1 - 0.002 17.6 0.0 0.0046 16.4 0.0 1.6 1 0 0 1 1 1 1 Asparagine synthase AAA_28 PF13521.1 OAJ19127.1 - 0.013 15.4 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 OAJ19127.1 - 0.017 14.4 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B MobB PF03205.9 OAJ19127.1 - 0.027 14.1 0.1 0.051 13.2 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 OAJ19127.1 - 0.027 14.7 0.0 0.062 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NAD_synthase PF02540.12 OAJ19127.1 - 0.045 12.6 0.0 0.15 10.9 0.0 1.7 2 0 0 2 2 2 0 NAD synthase AAA_17 PF13207.1 OAJ19127.1 - 0.056 14.2 0.0 0.23 12.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 OAJ19127.1 - 0.11 11.2 0.2 0.21 10.3 0.1 1.3 1 0 0 1 1 1 0 ArgK protein AAA_29 PF13555.1 OAJ19127.1 - 0.13 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.16 OAJ19127.1 - 0.24 10.6 0.0 0.47 9.6 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Ribosomal_L22 PF00237.14 OAJ19155.1 - 1.9e-20 72.7 0.5 3.4e-20 71.9 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF2934 PF11154.3 OAJ19155.1 - 0.021 14.1 2.6 0.054 12.8 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) DUF3317 PF11779.3 OAJ19156.1 - 3.4e-06 26.3 0.4 5.4e-06 25.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Epiglycanin_C PF14654.1 OAJ19156.1 - 0.052 13.5 0.2 0.081 12.9 0.1 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region ADH_zinc_N PF00107.21 OAJ19159.1 - 5.1e-27 93.9 0.1 8e-27 93.3 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ19159.1 - 8.8e-10 39.5 0.0 2.2e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ19159.1 - 1.2e-09 37.9 0.0 2.7e-08 33.5 0.0 2.4 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain APH PF01636.18 OAJ19160.1 - 9.3e-20 71.3 0.4 9.3e-20 71.3 0.3 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 OAJ19160.1 - 0.043 13.1 0.0 0.84 8.9 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Myosin_N PF02736.14 OAJ19161.1 - 0.0017 17.9 4.0 0.0033 17.0 2.8 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF2945 PF11160.3 OAJ19161.1 - 0.057 13.2 2.1 0.086 12.6 1.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2945) SIR2 PF02146.12 OAJ19162.1 - 1.2e-28 100.0 0.0 5.6e-17 62.0 0.0 2.1 2 0 0 2 2 2 2 Sir2 family TIM21 PF08294.6 OAJ19163.1 - 1.1e-12 47.8 0.1 1.8e-11 43.8 0.0 2.6 2 1 0 2 2 2 1 TIM21 Aconitase_2_N PF06434.8 OAJ19164.1 - 0.054 12.8 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus CAF-1_p150 PF11600.3 OAJ19167.1 - 0.016 14.5 24.1 0.043 13.2 16.7 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SpoVR PF04293.8 OAJ19167.1 - 4 5.6 10.5 6.1 5.0 7.3 1.2 1 0 0 1 1 1 0 SpoVR like protein MFS_1 PF07690.11 OAJ19168.1 - 3.7e-38 131.1 39.9 3.7e-38 131.1 27.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EutH PF04346.7 OAJ19170.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.0 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH RabGAP-TBC PF00566.13 OAJ19199.1 - 5.4e-36 124.0 0.1 7.4e-36 123.6 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ADSL_C PF10397.4 OAJ19199.1 - 0.017 15.1 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus HemX PF04375.9 OAJ19199.1 - 5 5.6 4.4 7.5 5.0 3.1 1.2 1 0 0 1 1 1 0 HemX OTCace_N PF02729.16 OAJ19200.1 - 2.2e-43 147.3 0.1 3.2e-43 146.8 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 OAJ19200.1 - 1e-41 142.4 0.0 1.6e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Pribosyltran_N PF13793.1 OAJ19202.1 - 2.1e-44 149.9 0.0 9.6e-43 144.6 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 OAJ19202.1 - 9.9e-35 119.9 3.0 2.8e-31 108.6 0.4 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 OAJ19202.1 - 2.7e-14 52.9 0.3 5.2e-13 48.8 0.3 2.7 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 OAJ19202.1 - 0.011 14.9 0.1 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Rft-1 PF04506.8 OAJ19203.1 - 4.9e-64 216.6 0.7 1.1e-62 212.2 0.2 2.7 2 1 0 2 2 2 1 Rft protein Git3 PF11710.3 OAJ19204.1 - 6.6e-10 38.8 8.8 1.6e-09 37.6 6.1 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 OAJ19204.1 - 1.3e-08 34.3 0.0 4e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 OAJ19204.1 - 0.00052 19.7 0.7 0.0022 17.6 0.0 2.3 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Flu_M2 PF00599.12 OAJ19204.1 - 0.76 9.6 1.7 2.3 8.0 0.0 2.6 3 0 0 3 3 3 0 Influenza Matrix protein (M2) MULE PF10551.4 OAJ19205.1 - 4e-18 65.3 0.1 1.1e-17 63.9 0.1 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ19205.1 - 8e-08 31.2 0.1 8e-08 31.2 0.1 1.7 2 0 0 2 2 2 1 Transposase, Mutator family FAR1 PF03101.10 OAJ19205.1 - 2.2e-05 24.8 0.0 4.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain DDE_Tnp_IS240 PF13610.1 OAJ19205.1 - 0.00023 21.1 0.0 0.00054 19.9 0.0 1.6 1 0 0 1 1 1 1 DDE domain DDE_Tnp_ISL3 PF01610.12 OAJ19205.1 - 0.00047 19.8 0.1 0.0018 17.8 0.0 1.8 1 1 1 2 2 2 1 Transposase rve PF00665.21 OAJ19205.1 - 0.029 14.4 0.1 0.087 12.9 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Na_trans_assoc PF06512.8 OAJ19205.1 - 1.2 9.0 5.8 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Sodium ion transport-associated Abhydrolase_1 PF00561.15 OAJ19206.1 - 1.4e-26 93.5 0.4 3.4e-12 46.4 0.0 3.2 3 0 0 3 3 3 3 alpha/beta hydrolase fold COX6A PF02046.10 OAJ19208.1 - 5.5e-29 100.4 0.1 6.3e-29 100.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Xpo1 PF08389.7 OAJ19243.1 - 0.003 17.4 0.0 0.0065 16.3 0.0 1.5 1 0 0 1 1 1 1 Exportin 1-like protein p450 PF00067.17 OAJ19244.1 - 1.8e-05 23.4 0.0 1.8e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sporozoite_P67 PF05642.6 OAJ19245.1 - 0.2 9.5 21.3 0.23 9.2 14.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen D123 PF07065.9 OAJ19245.1 - 2.2 7.2 12.6 2.4 7.1 8.8 1.1 1 0 0 1 1 1 0 D123 POX PF07526.6 OAJ19245.1 - 3 8.0 11.2 3.6 7.8 7.8 1.2 1 0 0 1 1 1 0 Associated with HOX Endonuc_Holl PF10107.4 OAJ19245.1 - 8.5 6.0 9.5 9.5 5.8 6.6 1.0 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF3381 PF11861.3 OAJ19245.1 - 9.1 5.7 27.0 10 5.5 18.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) YqfQ PF14181.1 OAJ19245.1 - 9.8 6.1 19.3 11 6.0 13.4 1.1 1 0 0 1 1 1 0 YqfQ-like protein Fasciclin PF02469.17 OAJ19246.1 - 3e-11 43.4 0.0 4.1e-08 33.2 0.0 2.7 2 1 0 2 2 2 2 Fasciclin domain DDE_1 PF03184.14 OAJ19247.1 - 1.2e-28 99.6 0.0 1.5e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease FAD_binding_7 PF03441.9 OAJ19248.1 - 2e-67 227.3 0.6 1.7e-49 168.4 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 OAJ19248.1 - 2.4e-35 121.7 0.0 4.1e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase zf-H2C2_2 PF13465.1 OAJ19249.1 - 4.8e-13 48.6 7.5 2.7e-05 24.2 0.0 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ19249.1 - 1.1e-08 34.9 25.2 0.00024 21.2 0.5 4.9 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ19249.1 - 1.9e-08 34.0 24.4 0.00019 21.4 0.0 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-BED PF02892.10 OAJ19249.1 - 0.024 14.3 0.0 0.024 14.3 0.0 3.3 3 1 1 4 4 4 0 BED zinc finger zf-C2HC_2 PF13913.1 OAJ19249.1 - 0.26 10.9 7.8 0.048 13.3 0.6 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TauD PF02668.11 OAJ19250.1 - 1.3e-34 120.0 0.1 4.4e-34 118.3 0.0 1.8 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 OAJ19250.1 - 0.00014 22.2 4.7 0.00017 21.9 0.4 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF971) SurE PF01975.12 OAJ19250.1 - 0.09 12.0 0.8 0.15 11.3 0.6 1.3 1 0 0 1 1 1 0 Survival protein SurE Glyco_hydro_cc PF11790.3 OAJ19251.1 - 4.3e-50 170.3 2.0 5.4e-50 170.0 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core VPS28 PF03997.7 OAJ19286.1 - 7.7e-44 149.5 0.0 1.5e-43 148.6 0.0 1.5 1 1 0 1 1 1 1 VPS28 protein DUF469 PF04320.9 OAJ19286.1 - 0.047 14.4 0.0 0.18 12.5 0.0 1.9 2 1 0 2 2 2 0 Protein with unknown function (DUF469) PAPS_reduct PF01507.14 OAJ19287.1 - 1.2e-36 126.1 0.0 1.6e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HHV6-IE PF03753.8 OAJ19288.1 - 9.5 3.5 13.2 12 3.2 9.2 1.1 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Myb_DNA-bind_3 PF12776.2 OAJ19289.1 - 0.00036 21.1 0.5 0.0028 18.2 0.0 2.5 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MBF1 PF08523.5 OAJ19291.1 - 7.1e-13 48.3 0.5 1.6e-12 47.2 0.3 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 OAJ19291.1 - 1.7e-11 43.7 0.3 3.1e-11 42.9 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 OAJ19291.1 - 5.4e-06 26.3 0.1 7.6e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 OAJ19291.1 - 0.00033 20.8 0.0 0.00053 20.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HpcH_HpaI PF03328.9 OAJ19291.1 - 0.027 13.3 0.0 0.029 13.2 0.0 1.2 1 1 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family SNF5 PF04855.7 OAJ19292.1 - 3.9e-51 173.8 2.3 4.3e-50 170.4 1.6 2.0 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 ECF-ribofla_trS PF07155.7 OAJ19293.1 - 0.039 13.6 1.7 0.093 12.4 1.1 1.6 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component PrgI PF12666.2 OAJ19293.1 - 0.26 11.4 1.7 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 PrgI family protein X PF00739.14 OAJ19294.1 - 3.7 7.4 5.6 7 6.5 3.9 1.5 1 0 0 1 1 1 0 Trans-activation protein X Polysacc_synt_4 PF04669.8 OAJ19295.1 - 3.6e-25 88.4 4.0 2e-24 86.0 2.8 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis RRP14 PF15459.1 OAJ19295.1 - 0.18 11.8 3.2 0.51 10.4 2.2 1.9 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 NDUF_B12 PF08122.7 OAJ19296.1 - 5.4e-18 64.4 0.2 9.5e-18 63.6 0.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family TPR_12 PF13424.1 OAJ19297.1 - 0.00046 20.0 0.9 0.0023 17.8 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ19297.1 - 0.0073 16.1 0.1 11 6.2 0.0 3.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ19297.1 - 0.036 14.2 0.4 0.14 12.2 0.3 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Pkinase PF00069.20 OAJ19298.1 - 1e-40 139.5 0.0 1.1e-27 96.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ19298.1 - 1.2e-23 83.4 0.0 1.8e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ19298.1 - 0.038 12.9 0.0 0.091 11.6 0.0 1.6 1 0 0 1 1 1 0 Kinase-like RRM_1 PF00076.17 OAJ19299.1 - 1e-15 57.0 0.0 2e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ19299.1 - 8.6e-14 51.2 0.0 1.4e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ19299.1 - 2.4e-09 36.8 0.0 3.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGI PF00342.14 OAJ19300.1 - 7e-209 694.2 0.0 8.7e-209 693.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase F1F0-ATPsyn_F PF10791.4 OAJ19301.1 - 1.6e-33 114.7 0.1 2e-33 114.4 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Hexapep PF00132.19 OAJ19302.1 - 3.3e-09 35.8 7.5 3.8e-05 22.9 0.6 4.1 2 2 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 OAJ19302.1 - 0.00011 21.7 8.2 0.25 10.9 0.0 3.6 3 2 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 OAJ19302.1 - 0.09 11.3 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 L-fucokinase DUF2673 PF10880.3 OAJ19340.1 - 0.034 14.1 0.1 0.042 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) zf-ribbon_3 PF13248.1 OAJ19341.1 - 0.058 12.6 4.8 0.058 12.6 3.4 2.4 1 1 1 2 2 2 0 zinc-ribbon domain Aminotran_4 PF01063.14 OAJ19343.1 - 3.5e-21 75.7 0.0 5.8e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV tRNA_U5-meth_tr PF05958.6 OAJ19344.1 - 2.6e-18 65.8 0.0 6.4e-17 61.2 0.0 2.4 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_26 PF13659.1 OAJ19344.1 - 6.7e-07 29.3 0.0 1.2e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ19344.1 - 3.3e-06 26.7 0.0 5.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 OAJ19344.1 - 3.5e-05 23.4 0.0 6.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TRAM PF01938.15 OAJ19344.1 - 8.2e-05 22.3 1.4 0.00018 21.2 0.9 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_18 PF12847.2 OAJ19344.1 - 0.00071 20.1 0.0 0.002 18.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ19344.1 - 0.0039 16.5 0.0 0.009 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.6 OAJ19344.1 - 0.0052 16.2 0.0 0.0095 15.3 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Met_10 PF02475.11 OAJ19344.1 - 0.0062 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein MEF2_binding PF09047.5 OAJ19344.1 - 0.017 14.7 0.1 2.6 7.7 0.0 2.9 2 0 0 2 2 2 0 MEF2 binding PrmA PF06325.8 OAJ19344.1 - 0.02 14.0 0.0 0.044 12.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SKN1 PF03935.10 OAJ19345.1 - 3.5e-181 602.7 0.5 4.4e-181 602.4 0.3 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 OAJ19345.1 - 4.9e-07 29.2 0.1 0.00024 20.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 EF-hand_5 PF13202.1 OAJ19345.1 - 0.065 12.5 0.0 0.22 10.9 0.0 1.9 1 0 0 1 1 1 0 EF hand Acyltransferase PF01553.16 OAJ19349.1 - 1.2e-23 82.9 0.0 2e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Form-deh_trans PF09163.6 OAJ19349.1 - 0.043 13.3 0.2 0.081 12.4 0.1 1.4 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane Wzy_C PF04932.10 OAJ19350.1 - 7 6.4 10.5 6.6 6.5 1.8 2.9 3 1 0 3 3 3 0 O-Antigen ligase Actin PF00022.14 OAJ19386.1 - 8.8e-20 70.4 0.0 7.6e-11 41.0 0.0 3.2 3 0 0 3 3 3 3 Actin SAC3_GANP PF03399.11 OAJ19387.1 - 5.6e-69 231.7 1.5 7.6e-69 231.3 1.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 OAJ19387.1 - 0.0035 17.0 0.8 0.0081 15.9 0.1 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 Nha1_C PF08619.5 OAJ19387.1 - 0.024 13.9 0.6 0.033 13.4 0.4 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF917 PF06032.7 OAJ19388.1 - 0.2 10.1 0.0 0.29 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) DUF605 PF04652.11 OAJ19388.1 - 1.3 8.3 11.7 0.011 15.1 1.5 2.1 2 0 0 2 2 2 0 Vta1 like p47_phox_C PF08944.6 OAJ19389.1 - 0.52 10.5 3.1 3.3 7.9 0.2 2.4 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain DUF3188 PF11384.3 OAJ19390.1 - 0.01 15.4 1.1 0.02 14.4 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3188) PspB PF06667.7 OAJ19390.1 - 0.025 14.5 0.1 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 Phage shock protein B PgaD PF13994.1 OAJ19390.1 - 0.026 13.9 0.2 0.053 12.9 0.2 1.4 1 0 0 1 1 1 0 PgaD-like protein Neur_chan_memb PF02932.11 OAJ19390.1 - 0.51 10.1 5.2 0.7 9.7 2.4 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2500 PF10694.4 OAJ19390.1 - 7.8 6.5 6.0 3.9 7.5 1.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2500) YEATS PF03366.11 OAJ19391.1 - 1.4e-31 108.0 0.0 2.9e-31 107.0 0.0 1.5 1 1 0 1 1 1 1 YEATS family NTR2 PF15458.1 OAJ19391.1 - 0.0059 15.8 1.5 0.0086 15.3 1.0 1.2 1 0 0 1 1 1 1 Nineteen complex-related protein 2 OPA3 PF07047.7 OAJ19391.1 - 0.027 14.2 0.2 0.046 13.5 0.1 1.4 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) DUF2570 PF10828.3 OAJ19391.1 - 4.1 7.0 5.9 1.2 8.7 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Kinesin PF00225.18 OAJ19392.1 - 1e-93 313.6 0.5 1.3e-92 310.0 0.0 2.2 2 1 0 2 2 2 1 Kinesin motor domain Surfac_D-trimer PF09006.6 OAJ19392.1 - 0.037 13.7 4.7 0.045 13.4 2.1 2.1 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Macoilin PF09726.4 OAJ19392.1 - 0.62 8.2 20.6 1.5 7.0 14.2 1.6 1 1 0 1 1 1 0 Transmembrane protein Filament PF00038.16 OAJ19392.1 - 1.2 8.5 26.4 0.36 10.2 7.5 2.3 1 1 1 2 2 2 0 Intermediate filament protein Bacillus_HBL PF05791.6 OAJ19392.1 - 2.3 7.5 10.7 0.054 12.8 1.6 2.3 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) BAG PF02179.11 OAJ19393.1 - 1.7e-12 47.2 0.2 2e-11 43.8 0.1 2.2 2 0 0 2 2 2 1 BAG domain ubiquitin PF00240.18 OAJ19393.1 - 4.1e-08 32.4 0.0 7.2e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 OAJ19393.1 - 0.013 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain TarH PF02203.10 OAJ19393.1 - 0.061 13.1 5.0 0.096 12.5 3.4 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue DUF3824 PF12868.2 OAJ19393.1 - 0.54 11.1 8.8 0.061 14.2 3.0 1.6 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Thioredoxin_8 PF13905.1 OAJ19394.1 - 2.8e-10 40.1 0.1 1.1e-09 38.2 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 OAJ19394.1 - 0.00071 19.1 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAJ19394.1 - 0.01 15.5 0.0 0.036 13.7 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA family DUF3439 PF11921.3 OAJ19394.1 - 0.27 10.9 10.0 0.52 10.0 6.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 OAJ19394.1 - 0.59 9.8 15.7 1 9.1 10.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Anoctamin PF04547.7 OAJ19395.1 - 4.7e-96 322.1 0.0 5.9e-96 321.8 0.0 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Glu_synthase PF01645.12 OAJ19397.1 - 6.6e-160 532.0 0.1 1.9e-159 530.4 0.0 1.8 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 OAJ19397.1 - 3.1e-139 463.6 0.0 4.3e-139 463.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 OAJ19397.1 - 4.6e-116 387.1 0.0 7.5e-116 386.4 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 OAJ19397.1 - 2.6e-68 228.9 1.6 2.6e-68 228.9 1.1 2.0 2 0 0 2 2 2 1 GXGXG motif Fer4_20 PF14691.1 OAJ19397.1 - 7.8e-23 80.2 0.0 2.2e-22 78.7 0.0 1.8 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 OAJ19397.1 - 9.3e-20 71.3 0.0 6.9e-19 68.5 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAJ19397.1 - 8.7e-10 38.9 0.2 8.3e-05 22.7 0.1 2.9 2 1 1 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAJ19397.1 - 2.2e-09 37.1 0.0 8.4e-09 35.3 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAJ19397.1 - 7.7e-08 32.6 0.2 0.00014 22.1 0.2 3.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 OAJ19397.1 - 2.3e-07 30.2 0.1 3.6e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 OAJ19397.1 - 3.9e-05 22.9 0.2 9.5e-05 21.6 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 OAJ19397.1 - 6.1e-05 22.0 0.3 6.1e-05 22.0 0.2 2.0 2 0 0 2 2 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 OAJ19397.1 - 7.6e-05 21.3 0.1 7.6e-05 21.3 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 OAJ19397.1 - 7.9e-05 22.2 0.0 0.016 14.7 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 OAJ19397.1 - 0.00023 20.3 0.2 0.00023 20.3 0.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 OAJ19397.1 - 0.00028 19.8 2.6 0.00047 19.1 0.2 2.6 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.14 OAJ19397.1 - 0.00057 19.0 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FMN_dh PF01070.13 OAJ19397.1 - 0.003 16.4 1.4 0.079 11.7 0.8 2.8 3 0 0 3 3 3 1 FMN-dependent dehydrogenase DJ-1_PfpI PF01965.19 OAJ19397.1 - 0.0055 16.1 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 DJ-1/PfpI family NAD_binding_7 PF13241.1 OAJ19397.1 - 0.0071 16.5 1.1 0.44 10.8 0.1 3.1 2 0 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.17 OAJ19397.1 - 0.008 15.0 0.6 0.05 12.4 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 OAJ19397.1 - 0.013 14.6 0.1 0.073 12.2 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 OAJ19397.1 - 0.013 15.2 0.1 0.032 13.9 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GATase_6 PF13522.1 OAJ19397.1 - 0.029 14.3 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain Lycopene_cycl PF05834.7 OAJ19397.1 - 0.05 12.5 0.2 4.8 5.9 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 OAJ19397.1 - 0.056 13.2 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding AdoHcyase_NAD PF00670.16 OAJ19397.1 - 0.19 11.5 3.4 12 5.6 0.0 3.5 4 0 0 4 4 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.15 OAJ19397.1 - 0.29 11.2 1.4 11 6.1 0.0 3.1 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 OAJ19397.1 - 0.47 8.5 0.0 1.1 7.3 0.0 1.6 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like MFS_1 PF07690.11 OAJ19431.1 - 3.2e-38 131.3 38.7 5.5e-32 110.8 12.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WCOR413 PF05562.6 OAJ19431.1 - 0.47 9.9 5.4 1.5 8.3 0.5 3.2 3 0 0 3 3 3 0 Cold acclimation protein WCOR413 DUF2484 PF10658.4 OAJ19431.1 - 0.56 10.3 11.3 0.024 14.7 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) RabGAP-TBC PF00566.13 OAJ19432.1 - 1.1e-21 77.3 3.3 9.4e-18 64.4 0.6 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Hydrophob_seed PF14547.1 OAJ19432.1 - 0.024 14.5 0.1 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 Hydrophobic seed protein UCH PF00443.24 OAJ19434.1 - 2.7e-30 105.3 0.0 5.9e-30 104.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 OAJ19434.1 - 3.8e-11 42.9 0.0 6.4e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 OAJ19434.1 - 6.5e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Mito_carr PF00153.22 OAJ19435.1 - 7e-49 163.5 9.3 6.2e-16 57.8 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SNF2_N PF00176.18 OAJ19436.1 - 4e-63 213.0 0.2 6.1e-63 212.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ19436.1 - 1.3e-08 34.5 0.0 2.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain XPG_I PF00867.13 OAJ19436.1 - 1.6e-08 34.4 0.0 1.6e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 XPG I-region zf-RING_5 PF14634.1 OAJ19436.1 - 1.8e-05 24.3 0.6 4.3e-05 23.1 0.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 OAJ19436.1 - 0.001 18.8 0.7 0.0022 17.7 0.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ19436.1 - 0.0012 18.8 4.1 0.0021 18.0 1.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ19436.1 - 0.0017 17.9 0.7 0.0017 17.9 0.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) XPG_N PF00752.12 OAJ19436.1 - 0.0051 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 OAJ19436.1 - 0.02 15.0 0.0 0.078 13.2 0.0 2.0 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold zf-RING_UBOX PF13445.1 OAJ19436.1 - 0.044 13.5 0.1 0.099 12.3 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 OAJ19436.1 - 0.078 12.8 1.4 0.26 11.1 1.0 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Glypican PF01153.14 OAJ19436.1 - 0.41 9.1 2.8 4.2 5.8 2.9 1.9 2 0 0 2 2 2 0 Glypican IF-2B PF01008.12 OAJ19437.1 - 1.4e-34 119.3 0.3 5.3e-31 107.6 0.0 2.8 3 0 0 3 3 3 2 Initiation factor 2 subunit family HSP90 PF00183.13 OAJ19437.1 - 3.3 5.9 6.9 4.7 5.4 4.8 1.1 1 0 0 1 1 1 0 Hsp90 protein DUF1244 PF06844.6 OAJ19438.1 - 0.084 12.7 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) zf-CCCH PF00642.19 OAJ19439.1 - 0.021 14.4 1.9 0.04 13.6 1.3 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MutS_V PF00488.16 OAJ19440.1 - 1.8e-71 240.2 0.0 1.3e-70 237.4 0.0 2.0 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAJ19440.1 - 1.3e-37 129.6 2.3 2.1e-37 128.9 1.6 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 OAJ19440.1 - 2.2e-23 82.4 0.0 6.9e-23 80.8 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 OAJ19440.1 - 6e-11 42.3 0.0 1.6e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 OAJ19440.1 - 6.4e-10 39.2 0.0 1.5e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain II COesterase PF00135.23 OAJ19475.1 - 1.6e-98 330.7 0.0 2.6e-98 330.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ19475.1 - 0.00021 20.9 0.1 0.00048 19.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAJ19475.1 - 0.0047 16.1 0.1 0.0084 15.3 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family ANTH PF07651.11 OAJ19476.1 - 3.6e-48 163.7 0.0 4.7e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 OAJ19476.1 - 3e-05 23.8 0.0 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 ENTH domain PARG_cat PF05028.9 OAJ19476.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) HSBP1 PF06825.7 OAJ19478.1 - 5.5e-11 41.8 0.1 7.9e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Vps16_C PF04840.7 OAJ19479.1 - 1.6e-06 27.3 0.7 0.02 13.8 0.0 2.0 2 0 0 2 2 2 2 Vps16, C-terminal region K_channel_TID PF07941.6 OAJ19479.1 - 0.00024 21.2 11.2 0.00024 21.2 7.8 2.3 3 0 0 3 3 3 1 Potassium channel Kv1.4 tandem inactivation domain Retinal PF15449.1 OAJ19479.1 - 2.5 5.6 14.4 3.1 5.3 10.0 1.1 1 0 0 1 1 1 0 Retinal protein Ribosomal_60s PF00428.14 OAJ19479.1 - 5.7 7.4 12.0 0.76 10.2 5.0 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein HAD_2 PF13419.1 OAJ19480.1 - 1.4e-23 83.9 0.5 2.5e-23 83.1 0.3 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 OAJ19480.1 - 1.6e-14 53.1 0.0 3e-06 26.8 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat F-box PF00646.28 OAJ19480.1 - 3.9e-06 26.3 0.1 1.1e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ19480.1 - 0.00015 21.3 0.1 0.00041 20.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 OAJ19480.1 - 0.12 10.4 0.1 0.44 8.6 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Mg_trans_NIPA PF05653.9 OAJ19481.1 - 7.5e-92 307.4 23.1 1.1e-91 306.9 16.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 OAJ19481.1 - 2.2e-05 24.5 8.4 2.2e-05 24.5 5.8 4.4 3 1 2 5 5 5 1 Multidrug resistance efflux transporter EamA PF00892.15 OAJ19481.1 - 0.00062 19.8 10.0 0.00062 19.8 6.9 3.8 2 2 1 3 3 3 1 EamA-like transporter family DUF2208 PF09973.4 OAJ19481.1 - 0.68 9.1 3.4 1.4 8.0 2.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) LRR_4 PF12799.2 OAJ19482.1 - 2.9e-49 163.9 56.2 1.3e-07 31.0 2.0 12.9 6 4 6 14 14 14 13 Leucine Rich repeats (2 copies) PP2C PF00481.16 OAJ19482.1 - 4.1e-48 163.9 0.0 7.5e-48 163.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 OAJ19482.1 - 1.6e-40 136.6 51.1 1.6e-10 40.5 0.6 9.6 4 2 8 12 12 12 11 Leucine rich repeat Guanylate_cyc PF00211.15 OAJ19482.1 - 3.4e-24 85.2 0.0 6e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 OAJ19482.1 - 1.5e-19 67.0 57.3 0.043 13.8 0.0 20.0 21 1 0 21 21 21 7 Leucine Rich Repeat LRR_7 PF13504.1 OAJ19482.1 - 1.8e-08 33.2 47.2 1.6 9.2 0.0 17.0 18 0 0 18 18 18 3 Leucine rich repeat RA PF00788.18 OAJ19482.1 - 8.5e-07 29.3 0.0 1.6e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_6 PF13516.1 OAJ19482.1 - 6.4e-06 25.7 44.5 2.1 8.6 0.1 15.2 15 0 0 15 15 15 1 Leucine Rich repeat LRR_5 PF13306.1 OAJ19482.1 - 0.0092 15.6 1.3 9.5 5.9 0.0 3.5 2 1 2 4 4 4 1 Leucine rich repeats (6 copies) Pkinase PF00069.20 OAJ19483.1 - 1.3e-52 178.5 0.0 1.3e-52 178.5 0.0 2.9 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ19483.1 - 5.9e-20 71.4 0.0 5.9e-20 71.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 OAJ19483.1 - 0.0027 17.4 0.0 0.0027 17.4 0.0 3.9 3 1 1 4 4 4 1 Phosphotransferase enzyme family Med15 PF09606.5 OAJ19483.1 - 0.021 13.0 148.2 0.0093 14.2 82.1 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Abhydrolase_9_N PF15420.1 OAJ19484.1 - 0.96 9.1 6.1 0.62 9.7 2.5 1.8 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus ABC_tran PF00005.22 OAJ19517.1 - 8.5e-29 100.6 0.0 1.9e-28 99.4 0.0 1.6 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 OAJ19517.1 - 4.9e-12 45.8 0.0 6.8e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 OAJ19517.1 - 1.1e-06 28.0 0.0 3.8e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAJ19517.1 - 0.00053 20.0 0.0 0.11 12.4 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_29 PF13555.1 OAJ19517.1 - 0.0035 16.8 0.4 0.0092 15.4 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.12 OAJ19517.1 - 0.011 15.5 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_17 PF13207.1 OAJ19517.1 - 0.012 16.4 0.1 0.032 15.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 OAJ19517.1 - 0.012 15.0 0.1 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 OAJ19517.1 - 0.023 14.6 0.4 0.18 11.7 0.2 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 OAJ19517.1 - 0.023 14.2 0.0 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 OAJ19517.1 - 0.031 13.4 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 OAJ19517.1 - 0.041 14.1 0.0 1.3 9.3 0.0 2.7 3 1 0 3 3 3 0 AAA domain ABC_ATPase PF09818.4 OAJ19517.1 - 0.064 11.8 0.0 0.12 10.9 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_22 PF13401.1 OAJ19517.1 - 0.069 13.2 0.0 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 OAJ19517.1 - 0.098 12.5 0.3 0.39 10.6 0.2 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 OAJ19517.1 - 0.12 11.8 0.0 0.49 9.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 OAJ19517.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 OAJ19517.1 - 0.13 11.2 0.0 0.37 9.8 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 OAJ19517.1 - 0.14 11.9 0.1 0.49 10.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain ABA_GPCR PF12430.3 OAJ19518.1 - 3.8e-34 117.5 4.0 8.3e-34 116.4 2.8 1.5 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 OAJ19518.1 - 1.4e-12 47.4 0.8 3.4e-12 46.2 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) LcrR PF09621.5 OAJ19518.1 - 0.044 13.0 0.4 0.1 11.8 0.1 1.7 2 0 0 2 2 2 0 Type III secretion system regulator (LcrR) SBDS PF01172.13 OAJ19519.1 - 2.3e-11 43.2 0.8 1.4e-10 40.8 0.6 1.9 1 1 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein PI3_PI4_kinase PF00454.22 OAJ19520.1 - 2.2e-32 112.4 0.0 3.5e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase K_oxygenase PF13434.1 OAJ19521.1 - 9.3e-87 291.1 0.0 1.8e-86 290.1 0.0 1.5 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAJ19521.1 - 1.1e-08 35.0 0.0 2.7e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 OAJ19521.1 - 4.8e-05 23.5 0.0 0.00033 20.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ19521.1 - 0.0071 16.7 0.0 0.035 14.5 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 OAJ19522.1 - 8.8e-09 35.9 0.0 1.7e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ19522.1 - 1.5e-05 24.8 0.0 3.6e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ19522.1 - 0.00025 20.6 0.2 0.00049 19.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 OAJ19522.1 - 0.0033 16.9 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 OAJ19522.1 - 0.05 14.1 0.0 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ19522.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 OAJ19522.1 - 0.091 12.1 0.2 0.26 10.6 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_9 PF08003.6 OAJ19522.1 - 0.18 10.4 0.0 0.32 9.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MRP-L20 PF12824.2 OAJ19523.1 - 3.7e-20 72.5 0.1 5.9e-20 71.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 GntR PF00392.16 OAJ19523.1 - 0.12 11.8 0.1 0.37 10.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_AsnC-type PF13404.1 OAJ19523.1 - 0.86 9.1 0.0 0.86 9.1 0.0 2.8 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain PEPCK_ATP PF01293.15 OAJ19524.1 - 8.1e-214 710.3 0.0 9.7e-214 710.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 OAJ19524.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAJ19524.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.18 OAJ19526.1 - 2.7e-76 256.6 22.7 7.1e-43 146.9 3.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ19526.1 - 1.1e-31 109.9 0.0 1.9e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 OAJ19526.1 - 2.5e-06 26.9 0.2 5.2e-05 22.5 0.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 OAJ19526.1 - 0.0032 16.9 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF87 PF01935.12 OAJ19526.1 - 0.006 16.4 0.1 0.011 15.5 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function DUF87 AAA_22 PF13401.1 OAJ19526.1 - 0.013 15.6 0.9 2.4 8.3 0.6 2.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 OAJ19526.1 - 0.014 14.9 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.4 OAJ19526.1 - 0.018 13.6 0.0 0.031 12.8 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_17 PF13207.1 OAJ19526.1 - 0.026 15.3 0.0 0.055 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 OAJ19526.1 - 0.075 13.0 1.2 0.19 11.6 0.4 2.0 2 1 0 2 2 2 0 AAA ATPase domain Period_C PF12114.3 OAJ19527.1 - 0.45 10.0 6.1 0.15 11.6 1.6 1.9 1 1 0 2 2 2 0 Period protein 2/3C-terminal region Cnd3 PF12719.2 OAJ19563.1 - 1.2e-78 264.1 0.0 1.1e-75 254.3 0.0 3.1 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 OAJ19563.1 - 9.3e-06 25.8 17.0 0.00068 19.8 1.2 6.0 5 1 1 6 6 6 3 HEAT repeats HEAT PF02985.17 OAJ19563.1 - 0.00057 19.7 6.1 21 5.5 0.0 6.9 8 0 0 8 8 8 2 HEAT repeat FANCI_S2 PF14676.1 OAJ19563.1 - 0.015 15.2 0.2 4.9 7.0 0.0 2.7 2 0 0 2 2 2 0 FANCI solenoid 2 Cnd1 PF12717.2 OAJ19563.1 - 0.035 13.9 2.3 0.95 9.2 0.1 3.2 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 OAJ19563.1 - 0.58 10.7 13.5 34 5.1 0.0 6.4 6 0 0 6 6 6 0 HEAT-like repeat Homeobox PF00046.24 OAJ19564.1 - 6.1e-19 67.3 4.8 1.2e-18 66.5 3.4 1.5 1 0 0 1 1 1 1 Homeobox domain Rad4 PF03835.10 OAJ19565.1 - 3.2e-27 94.7 0.0 3.2e-27 94.7 0.0 2.4 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 OAJ19565.1 - 1.9e-23 81.9 0.0 3.5e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 OAJ19565.1 - 2.4e-18 65.4 0.0 4.4e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.14 OAJ19565.1 - 7.8e-08 32.5 1.1 7e-07 29.4 0.0 3.1 3 0 0 3 3 3 1 Transglutaminase-like superfamily BHD_2 PF10404.4 OAJ19565.1 - 0.016 15.4 0.3 0.016 15.4 0.2 3.5 4 1 0 4 4 4 0 Rad4 beta-hairpin domain 2 EBP PF05241.7 OAJ19566.1 - 1.7e-56 190.2 9.0 2.1e-56 190.0 6.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein NAD_binding_8 PF13450.1 OAJ19566.1 - 0.0036 17.2 0.1 0.0095 15.9 0.0 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HR_lesion PF05514.6 OAJ19566.1 - 0.082 12.7 2.2 0.64 9.8 0.1 2.4 2 0 0 2 2 2 0 HR-like lesion-inducing PDZ_2 PF13180.1 OAJ19567.1 - 1.2e-05 25.1 0.0 2.8e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.19 OAJ19567.1 - 0.00021 21.3 0.0 0.00048 20.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 OAJ19567.1 - 0.1 12.5 0.0 0.36 10.8 0.0 1.7 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain dCMP_cyt_deam_1 PF00383.17 OAJ19569.1 - 1.4e-24 85.6 0.8 2.5e-24 84.8 0.6 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 OAJ19569.1 - 0.00037 21.2 0.0 0.001 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ19569.1 - 0.0032 17.3 0.0 0.0082 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ19569.1 - 0.0055 17.0 0.0 0.019 15.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAJ19569.1 - 0.16 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TRAM_LAG1_CLN8 PF03798.11 OAJ19570.1 - 2.2e-31 108.9 24.3 2.2e-31 108.9 16.9 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 OAJ19570.1 - 1.5e-12 46.8 0.0 4.5e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein Transket_pyr PF02779.19 OAJ19573.1 - 6.8e-61 204.8 0.0 1e-60 204.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 OAJ19573.1 - 2.7e-59 200.3 0.0 4.4e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TMEM171 PF15471.1 OAJ19573.1 - 7.3 5.2 6.0 12 4.6 4.2 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 tRNA-synt_2b PF00587.20 OAJ19574.1 - 2.7e-65 219.1 0.0 3.9e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ19574.1 - 4.4e-21 74.6 0.4 1.4e-20 72.9 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain Mito_carr PF00153.22 OAJ19575.1 - 2.1e-43 145.9 10.5 3.5e-16 58.6 0.5 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF508 PF04370.7 OAJ19575.1 - 0.53 9.9 2.9 0.87 9.1 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Sdh_cyt PF01127.17 OAJ19614.1 - 0.00036 20.3 1.9 0.0032 17.3 0.2 2.6 2 1 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1691 PF07950.6 OAJ19614.1 - 0.0013 18.6 1.5 0.0013 18.6 1.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1691) Yip1 PF04893.12 OAJ19615.1 - 3.3e-09 36.4 11.5 3.3e-09 36.4 8.0 1.5 2 0 0 2 2 2 1 Yip1 domain UBA PF00627.26 OAJ19616.1 - 0.0031 17.3 0.0 0.0063 16.3 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain SAICAR_synt PF01259.13 OAJ19617.1 - 2.8e-76 255.9 0.0 4.2e-58 196.3 0.0 2.1 2 0 0 2 2 2 2 SAICAR synthetase Pro-kuma_activ PF09286.6 OAJ19617.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain SCA7 PF08313.7 OAJ19618.1 - 7e-26 89.6 0.2 1.8e-25 88.3 0.1 1.6 1 0 0 1 1 1 1 SCA7, zinc-binding domain Pro-kuma_activ PF09286.6 OAJ19619.1 - 1e-16 61.2 0.0 2.4e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 OAJ19619.1 - 1.6e-13 50.4 0.7 4.5e-13 48.9 0.3 1.6 1 1 0 1 1 1 1 Subtilase family OmpA PF00691.15 OAJ19619.1 - 0.12 12.7 0.0 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 OmpA family Jiraiya PF15038.1 OAJ19620.1 - 0.049 13.0 0.0 0.06 12.7 0.0 1.1 1 0 0 1 1 1 0 Jiraiya DUF427 PF04248.7 OAJ19621.1 - 5.6e-28 96.4 0.9 9.8e-27 92.4 0.1 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF427) Peptidase_M43 PF05572.8 OAJ19622.1 - 4.3e-08 32.9 0.0 5.7e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A LCM PF04072.9 OAJ19625.1 - 3.6e-16 59.2 0.0 2.2e-15 56.7 0.0 2.1 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase PC_rep PF01851.17 OAJ19626.1 - 2.4e-45 150.2 17.6 3.7e-09 36.3 0.0 10.1 10 0 0 10 10 10 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 OAJ19626.1 - 4.6e-22 78.1 7.3 3.2e-11 43.3 0.0 5.0 2 1 4 6 6 6 5 HEAT repeats HEAT PF02985.17 OAJ19626.1 - 2.1e-07 30.4 2.5 1.4 9.2 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 OAJ19626.1 - 2.4e-07 31.0 8.3 0.025 15.0 0.1 5.5 4 1 2 6 6 6 3 HEAT-like repeat HEAT_PBS PF03130.11 OAJ19626.1 - 0.0035 17.6 2.1 59 4.5 0.0 5.9 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat DUF3439 PF11921.3 OAJ19626.1 - 1.5 8.5 4.0 3.5 7.4 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TPR_19 PF14559.1 OAJ19626.1 - 2 8.8 9.6 3.2 8.1 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 OAJ19627.1 - 1.3e-11 44.8 0.8 7.6e-05 22.6 0.6 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ19627.1 - 2.2e-11 43.6 0.1 3.2e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 OAJ19627.1 - 1.8e-08 34.1 0.1 1.3e-05 24.7 0.0 2.1 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 OAJ19627.1 - 8.7e-08 31.9 0.1 0.0079 15.7 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 OAJ19627.1 - 0.042 13.2 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 OAJ19627.1 - 0.046 13.5 0.1 0.13 12.1 0.0 1.9 1 1 0 1 1 1 0 Putative lysophospholipase Ku PF02735.11 OAJ19665.1 - 3.4e-17 62.5 0.2 6.8e-16 58.2 0.0 3.0 3 1 0 3 3 3 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 OAJ19665.1 - 4e-12 46.0 0.1 9.9e-12 44.8 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.10 OAJ19665.1 - 0.0027 17.1 0.0 0.078 12.3 0.0 2.7 3 1 0 3 3 3 1 Ku70/Ku80 N-terminal alpha/beta domain Ehbp PF10622.4 OAJ19665.1 - 0.064 13.2 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 Energy-converting hydrogenase B subunit P (EhbP) Pyridoxal_deC PF00282.14 OAJ19666.1 - 4.6e-63 212.9 0.0 7e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 OAJ19666.1 - 0.0025 16.6 0.0 0.0039 16.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V GMP_synt_C PF00958.17 OAJ19667.1 - 2.7e-41 139.1 0.0 5.2e-41 138.2 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 OAJ19667.1 - 4.8e-36 124.0 0.0 7.9e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 OAJ19667.1 - 5.4e-11 41.8 0.1 1e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 OAJ19667.1 - 1e-09 38.1 0.0 2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 OAJ19667.1 - 0.0006 18.4 0.2 0.001 17.6 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 OAJ19667.1 - 0.0011 18.4 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 OAJ19667.1 - 0.0018 17.8 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 OAJ19667.1 - 0.016 14.4 0.0 0.24 10.6 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.15 OAJ19667.1 - 0.049 13.1 0.1 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 PP-loop family Arginosuc_synth PF00764.14 OAJ19667.1 - 0.062 12.3 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase DUF2392 PF10288.4 OAJ19667.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) Pil1 PF13805.1 OAJ19668.1 - 3.4e-26 91.9 0.1 9.4e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 Eisosome component PIL1 Spc7 PF08317.6 OAJ19668.1 - 0.12 11.0 0.6 0.21 10.1 0.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.7 OAJ19668.1 - 0.2 11.4 0.3 0.42 10.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) BAF1_ABF1 PF04684.8 OAJ19668.1 - 0.57 8.9 8.5 1.1 7.9 5.9 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF515 PF04415.7 OAJ19670.1 - 0.27 9.4 17.2 0.36 9.0 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) PAP1 PF08601.5 OAJ19670.1 - 0.38 10.3 8.3 0.45 10.1 5.8 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Pex14_N PF04695.8 OAJ19670.1 - 5.2 7.1 11.4 9.2 6.3 7.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RA PF00788.18 OAJ19671.1 - 1.3e-12 47.9 2.8 4.3e-10 39.9 0.0 3.1 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 OAJ19671.1 - 7.3e-07 28.4 0.0 1.5e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ19671.1 - 0.0011 18.4 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain MRI PF15325.1 OAJ19672.1 - 0.39 11.7 4.9 0.51 11.3 3.4 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection Macoilin PF09726.4 OAJ19672.1 - 8.1 4.5 8.1 8.4 4.5 5.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Hexapep PF00132.19 OAJ19673.1 - 1.6e-07 30.4 15.8 0.019 14.4 0.9 4.0 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 OAJ19673.1 - 0.00015 21.2 11.6 0.019 14.5 2.4 3.3 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase MIF4G PF02854.14 OAJ19674.1 - 2.7e-15 56.3 0.0 6.9e-15 55.0 0.0 1.7 1 1 0 1 1 1 1 MIF4G domain MA3 PF02847.12 OAJ19674.1 - 6.8e-10 38.6 0.0 1.6e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 MA3 domain Nop14 PF04147.7 OAJ19674.1 - 0.00027 19.0 23.8 0.00044 18.3 16.5 1.2 1 0 0 1 1 1 1 Nop14-like family DUF1290 PF06947.7 OAJ19674.1 - 0.12 12.3 0.2 0.24 11.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) COPI_C PF06957.6 OAJ19674.1 - 0.58 8.6 7.6 1.3 7.4 5.3 1.6 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus TFIIA PF03153.8 OAJ19674.1 - 5.5 6.7 31.0 0.048 13.5 15.6 1.8 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit COX5B PF01215.14 OAJ19675.1 - 8.7e-42 142.0 0.0 1.1e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.4 OAJ19675.1 - 0.0087 15.8 0.3 0.013 15.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger domain MSP1_C PF07462.6 OAJ19675.1 - 0.4 9.0 1.3 0.5 8.6 0.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Mito_carr PF00153.22 OAJ19676.1 - 3e-65 215.9 2.6 4.7e-23 80.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF605 PF04652.11 OAJ19710.1 - 9.3e-87 291.8 22.9 8.2e-86 288.7 15.9 2.0 1 1 0 1 1 1 1 Vta1 like Frag1 PF10277.4 OAJ19711.1 - 0.59 9.5 7.6 3.7 6.9 4.7 2.0 1 1 1 2 2 2 0 Frag1/DRAM/Sfk1 family DUF1129 PF06570.6 OAJ19711.1 - 2.4 7.4 4.0 4.2 6.6 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) GDA1_CD39 PF01150.12 OAJ19712.1 - 7.3e-72 242.2 0.0 6.5e-59 199.5 0.0 3.1 3 0 0 3 3 3 3 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 OAJ19712.1 - 0.043 13.0 0.0 0.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Translin PF01997.11 OAJ19713.1 - 2.5e-40 138.2 0.5 8.6e-38 129.9 0.3 2.4 1 1 0 1 1 1 1 Translin family THEG PF14912.1 OAJ19713.1 - 0.00043 20.7 1.0 0.00043 20.7 0.7 2.3 2 0 0 2 2 2 1 Testicular haploid expressed repeat Adeno_PIX PF03955.9 OAJ19713.1 - 1.3 9.5 4.9 19 5.8 0.0 3.0 3 1 0 3 3 3 0 Adenovirus hexon-associated protein (IX) DAO PF01266.19 OAJ19715.1 - 2e-41 142.1 0.3 3e-41 141.5 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ19715.1 - 0.00014 21.8 0.1 0.00031 20.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.10 OAJ19715.1 - 0.01 14.0 0.1 0.024 12.8 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.7 OAJ19715.1 - 0.018 13.9 0.1 0.068 12.0 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 OAJ19715.1 - 0.029 14.7 0.0 0.065 13.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 OAJ19715.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.1 OAJ19715.1 - 0.076 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SnoaL_2 PF12680.2 OAJ19715.1 - 0.14 12.5 0.0 0.46 10.9 0.0 1.8 1 0 0 1 1 1 0 SnoaL-like domain FAP PF07174.6 OAJ19716.1 - 0.013 14.7 32.4 0.024 13.9 22.5 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) TPR_11 PF13414.1 OAJ19717.1 - 1.8e-09 37.0 7.6 0.011 15.3 0.0 5.7 5 1 0 5 5 5 2 TPR repeat TPR_12 PF13424.1 OAJ19717.1 - 0.00046 20.0 16.3 1.3 9.0 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ19717.1 - 0.0005 20.4 13.8 25 5.8 0.2 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ19717.1 - 0.026 14.8 7.4 9.7 6.6 0.6 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ19717.1 - 0.035 14.0 7.8 1.6 8.8 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ19717.1 - 0.096 12.9 0.1 5.4 7.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ19717.1 - 0.1 12.2 0.3 18 5.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ19717.1 - 1.9 9.2 9.2 8.7 7.1 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat adh_short PF00106.20 OAJ19718.1 - 3.1e-31 108.5 2.2 4.6e-31 107.9 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ19718.1 - 2.1e-25 89.8 0.5 6.4e-25 88.3 0.4 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ19718.1 - 1e-16 61.1 0.6 1.7e-16 60.4 0.4 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 OAJ19718.1 - 0.00029 20.5 0.7 0.00049 19.7 0.5 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 OAJ19718.1 - 0.032 14.3 0.1 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 OAJ19718.1 - 0.061 12.4 0.2 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 OAJ19718.1 - 0.068 13.5 0.1 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ19718.1 - 0.085 13.3 0.1 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.16 OAJ19718.1 - 0.11 12.3 0.2 0.17 11.7 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.16 OAJ19718.1 - 0.8 9.2 3.6 0.2 11.2 0.2 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain E1-E2_ATPase PF00122.15 OAJ19719.1 - 1.3e-61 207.5 4.5 2.9e-61 206.4 1.9 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAJ19719.1 - 8.4e-46 155.7 4.8 5.4e-45 153.1 1.6 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ19719.1 - 1.3e-29 104.1 0.0 9.7e-23 81.6 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ19719.1 - 3.8e-19 68.4 0.0 7e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 OAJ19719.1 - 2.7e-18 65.1 0.0 6.5e-18 63.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 OAJ19719.1 - 1.5e-12 48.0 0.0 7.5e-12 45.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ19719.1 - 8.1e-05 22.3 1.8 0.0061 16.1 1.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 OAJ19719.1 - 0.018 15.2 0.0 0.066 13.4 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase RVT_3 PF13456.1 OAJ19748.1 - 0.024 14.4 0.0 0.064 13.0 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like TMEM151 PF14857.1 OAJ19749.1 - 0.0017 17.0 0.3 0.21 10.1 0.0 2.5 2 0 0 2 2 2 2 TMEM151 family DUF4448 PF14610.1 OAJ19749.1 - 1.2 8.6 3.8 17 4.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) TPR_12 PF13424.1 OAJ19751.1 - 7e-12 45.1 15.2 0.0022 17.9 0.0 4.9 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ19751.1 - 3.3e-11 42.1 4.2 0.13 12.2 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ19751.1 - 2.9e-08 32.9 2.2 1.5 8.6 0.2 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ19751.1 - 1.2e-07 31.2 6.5 0.15 11.7 0.0 4.6 3 2 0 3 3 3 3 TPR repeat TPR_8 PF13181.1 OAJ19751.1 - 7.8e-07 28.4 0.3 2.7 7.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ19751.1 - 8e-06 25.2 3.2 0.64 9.9 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ19751.1 - 4.9e-05 23.5 6.3 0.013 16.0 0.3 5.3 5 1 0 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ19751.1 - 0.00026 20.8 8.1 7.7 6.6 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc5 PF12862.2 OAJ19751.1 - 0.005 16.6 0.4 3.6 7.4 0.0 4.0 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 5 Apc3 PF12895.2 OAJ19751.1 - 0.0077 16.3 1.8 10 6.3 0.1 4.0 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 OAJ19751.1 - 0.0089 16.6 12.7 0.052 14.2 2.3 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ19751.1 - 0.031 14.7 4.0 20 5.9 0.1 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ19751.1 - 0.039 14.2 2.4 1.7 9.0 0.0 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ19751.1 - 0.36 11.4 0.2 0.36 11.4 0.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF4543 PF15076.1 OAJ19752.1 - 0.094 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) Glyco_transf_54 PF04666.8 OAJ19754.1 - 4e-08 32.3 0.0 0.011 14.4 0.0 3.1 3 0 0 3 3 3 3 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region MFS_1 PF07690.11 OAJ19755.1 - 6.7e-39 133.5 40.8 6.7e-39 133.5 28.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAJ19755.1 - 7.7e-13 47.4 16.3 9.9e-13 47.1 11.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PH_9 PF15410.1 OAJ19756.1 - 3.1e-05 24.1 0.6 0.11 12.6 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH PF00169.24 OAJ19756.1 - 0.0005 20.2 0.0 0.0044 17.1 0.0 2.3 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 OAJ19756.1 - 0.04 14.1 0.0 0.086 13.0 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Nop14 PF04147.7 OAJ19756.1 - 1.8 6.3 6.5 2.7 5.7 4.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 OAJ19756.1 - 5 5.0 7.9 11 3.9 5.5 1.5 1 0 0 1 1 1 0 CDC45-like protein FA_desaturase PF00487.19 OAJ19759.1 - 1.4e-12 47.6 9.6 2.2e-12 46.9 6.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Tfb2 PF03849.9 OAJ19790.1 - 2.2e-15 56.1 0.0 2.7e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Pkinase PF00069.20 OAJ19791.1 - 0.00092 18.4 0.0 0.001 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Aldedh PF00171.17 OAJ19792.1 - 7.4e-22 77.3 0.0 8.4e-22 77.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Macoilin PF09726.4 OAJ19793.1 - 0.0067 14.7 12.6 0.0084 14.4 8.8 1.1 1 0 0 1 1 1 1 Transmembrane protein GAGA_bind PF06217.7 OAJ19793.1 - 0.036 14.0 5.7 0.048 13.6 3.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.9 OAJ19793.1 - 0.67 7.9 13.0 0.87 7.5 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.1 OAJ19793.1 - 0.92 9.2 11.2 1.4 8.5 7.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Cwf_Cwc_15 PF04889.7 OAJ19793.1 - 1.4 8.6 16.8 2.2 7.9 11.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YqzE PF14038.1 OAJ19793.1 - 4.6 7.0 0.0 4.6 7.0 0.0 3.0 2 1 0 2 2 2 0 YqzE-like protein Nop14 PF04147.7 OAJ19793.1 - 6.4 4.5 16.9 8.3 4.1 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family TryThrA_C PF12319.3 OAJ19794.1 - 0.13 11.4 2.1 0.25 10.5 1.5 1.4 1 0 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal DUF2457 PF10446.4 OAJ19794.1 - 0.35 9.5 14.5 0.15 10.7 8.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Histone PF00125.19 OAJ19795.1 - 1.2e-28 99.0 0.4 1.2e-28 99.0 0.3 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ19795.1 - 7.5e-06 26.0 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 OAJ19795.1 - 0.0057 15.9 0.2 0.0057 15.9 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 OAJ19795.1 - 0.024 14.6 1.5 0.1 12.6 0.1 2.1 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3541 PF12060.3 OAJ19796.1 - 0.021 14.1 0.1 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) Ion_trans PF00520.26 OAJ19796.1 - 0.14 11.4 0.4 0.14 11.3 0.3 1.1 1 0 0 1 1 1 0 Ion transport protein tRNA-synt_2b PF00587.20 OAJ19797.1 - 1.1e-43 148.7 0.0 2e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ19797.1 - 2.1e-16 59.6 0.2 4.7e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 OAJ19797.1 - 7.5e-13 48.1 0.0 1.6e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 OAJ19797.1 - 7.4e-11 41.7 0.0 1.8e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF502 PF04367.8 OAJ19797.1 - 0.03 14.0 0.1 0.17 11.6 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF502) DUF4316 PF14195.1 OAJ19797.1 - 0.89 9.6 3.2 29 4.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) Peptidase_S8 PF00082.17 OAJ19798.1 - 9.5e-36 123.3 1.1 1.4e-35 122.8 0.7 1.3 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 OAJ19798.1 - 1.5e-08 35.0 0.0 3.1e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) zf-LYAR PF08790.6 OAJ19799.1 - 3.5e-11 42.5 0.9 3.5e-11 42.5 0.7 1.8 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DUF3133 PF11331.3 OAJ19799.1 - 0.34 10.5 1.9 3.1 7.4 1.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) eIF3_subunit PF08597.5 OAJ19800.1 - 1e-41 143.1 23.4 1.3e-41 142.8 16.2 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PBP1_TM PF14812.1 OAJ19800.1 - 0.028 14.7 33.9 0.063 13.5 6.1 3.4 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3246 PF11596.3 OAJ19800.1 - 0.053 12.8 6.4 0.083 12.1 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Merozoite_SPAM PF07133.6 OAJ19800.1 - 0.38 10.6 17.3 0.035 14.0 7.8 1.9 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Aldedh PF00171.17 OAJ19801.1 - 7.2e-15 54.2 0.1 8.4e-15 54.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1247 PF06851.6 OAJ19803.1 - 0.1 12.2 0.2 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1247) zf-BED PF02892.10 OAJ19805.1 - 0.055 13.2 0.3 0.086 12.6 0.2 1.3 1 0 0 1 1 1 0 BED zinc finger TMF_DNA_bd PF12329.3 OAJ19841.1 - 0.11 12.2 15.9 0.17 11.7 7.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3068 PF11271.3 OAJ19841.1 - 5.8 5.8 8.2 7.5 5.5 5.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3068) CENP-H PF05837.7 OAJ19841.1 - 6.6 6.9 19.0 9.4 6.4 3.9 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Cyclin PF08613.6 OAJ19842.1 - 7.6e-35 120.5 0.0 2e-21 76.9 0.0 2.4 2 0 0 2 2 2 2 Cyclin Pyridoxal_deC PF00282.14 OAJ19843.1 - 2.4e-26 92.0 0.0 3.1e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF2183 PF09949.4 OAJ19848.1 - 3e-25 88.0 0.0 5.5e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 OAJ19848.1 - 0.24 10.9 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) AAA PF00004.24 OAJ19849.1 - 1.4e-40 138.5 0.1 4.1e-40 137.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ19849.1 - 4.9e-05 23.3 2.5 0.0032 17.4 0.0 2.8 2 2 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 OAJ19849.1 - 0.00058 20.0 0.4 0.018 15.1 0.3 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAJ19849.1 - 0.00087 18.4 0.0 0.0019 17.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 OAJ19849.1 - 0.0014 17.9 0.0 0.0081 15.4 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_5 PF07728.9 OAJ19849.1 - 0.0014 18.3 0.7 0.0086 15.8 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 OAJ19849.1 - 0.0019 18.1 2.5 0.0065 16.3 0.0 2.7 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 OAJ19849.1 - 0.0023 18.7 0.1 0.0084 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Ribosomal_S19 PF00203.16 OAJ19849.1 - 0.0064 16.0 0.1 6.4 6.4 0.0 3.3 3 0 0 3 3 3 1 Ribosomal protein S19 AAA_19 PF13245.1 OAJ19849.1 - 0.0066 16.1 0.1 0.022 14.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 OAJ19849.1 - 0.0076 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 OAJ19849.1 - 0.0086 15.2 0.1 0.039 13.0 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 OAJ19849.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 OAJ19849.1 - 0.014 15.2 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 OAJ19849.1 - 0.049 13.1 2.4 1 8.9 0.0 2.2 1 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 OAJ19849.1 - 0.058 12.3 0.0 0.098 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 OAJ19849.1 - 0.072 12.4 2.9 0.18 11.1 0.1 2.5 2 1 1 3 3 3 0 AAA domain Cutinase PF01083.17 OAJ19850.1 - 8.1e-24 84.3 0.0 1e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ19850.1 - 2.1e-05 24.1 0.2 2.6e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ19850.1 - 0.0014 18.3 0.3 0.0022 17.7 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ19850.1 - 0.0047 16.8 1.0 0.027 14.3 0.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ19850.1 - 1.1 9.1 3.3 6.2 6.7 0.7 2.5 2 0 0 2 2 2 0 Putative lysophospholipase Rop PF01815.11 OAJ19851.1 - 0.12 11.7 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Rop protein G-gamma PF00631.17 OAJ19852.1 - 3e-22 78.1 0.0 3.3e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 GGL domain MelC1 PF06236.6 OAJ19853.1 - 0.039 13.9 2.4 0.12 12.3 0.8 2.1 1 1 1 2 2 2 0 Tyrosinase co-factor MelC1 DUF1155 PF06633.6 OAJ19853.1 - 0.14 11.4 0.1 0.52 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1155) Cutinase PF01083.17 OAJ19854.1 - 2.3e-25 89.3 0.0 2.8e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ19854.1 - 0.0011 18.5 0.1 0.0013 18.3 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ19854.1 - 0.0014 18.5 0.1 0.0016 18.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ19854.1 - 0.01 15.5 0.2 0.014 15.1 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Nsp3_PL2pro PF12124.3 OAJ19854.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain Fib_alpha PF08702.5 OAJ19855.1 - 0.1 12.7 0.3 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family YgaB PF14182.1 OAJ19855.1 - 0.14 12.3 1.5 0.24 11.6 0.7 1.6 1 1 0 1 1 1 0 YgaB-like protein Collagen PF01391.13 OAJ19889.1 - 1e-18 66.6 77.2 1.2e-10 40.7 24.9 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) SpoU_methylas_C PF12105.3 OAJ19890.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal TMEM141 PF15110.1 OAJ19893.1 - 0.2 11.9 1.6 7.3 6.9 0.1 2.4 2 0 0 2 2 2 0 TMEM141 protein family Cys_rich_CWC PF14375.1 OAJ19894.1 - 0.54 10.2 4.4 0.97 9.4 3.1 1.4 1 0 0 1 1 1 0 Cysteine-rich CWC Acetyltransf_1 PF00583.19 OAJ19896.1 - 0.00064 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ19896.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S8e PF01201.17 OAJ19897.1 - 8.8e-38 129.4 9.8 6.9e-37 126.5 6.8 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e Mer2 PF09074.5 OAJ19897.1 - 0.014 15.3 0.0 0.014 15.3 0.0 1.9 2 0 0 2 2 2 0 Mer2 Methyltransf_16 PF10294.4 OAJ19898.1 - 2.6e-12 46.5 0.2 3e-10 39.8 0.1 2.9 2 1 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 OAJ19898.1 - 0.0093 15.3 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 OAJ19898.1 - 0.022 14.7 0.1 0.043 13.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 OAJ19898.1 - 0.057 12.9 0.0 0.79 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.20 OAJ19899.1 - 4.8e-36 124.2 0.0 6.3e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ19899.1 - 1.4e-12 47.2 0.0 1.9e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Sporozoite_P67 PF05642.6 OAJ19899.1 - 0.13 10.0 13.0 0.17 9.6 9.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Phage_integrase PF00589.17 OAJ19900.1 - 2.8e-05 23.8 0.0 2.8e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family GSH_synth_ATP PF03917.12 OAJ19902.1 - 3.3e-78 262.8 0.0 7.7e-38 130.0 0.0 4.3 2 2 0 2 2 2 2 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 OAJ19902.1 - 3.7e-30 104.1 0.0 7.2e-30 103.1 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Dynamin_M PF01031.15 OAJ19933.1 - 1.6e-102 342.2 0.0 3.9e-102 341.0 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 OAJ19933.1 - 6.5e-55 185.4 0.1 1.7e-54 184.1 0.0 1.7 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 OAJ19933.1 - 7.6e-29 99.4 5.3 7.6e-29 99.4 3.7 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain IBN_N PF03810.14 OAJ19933.1 - 2.2e-06 27.4 0.1 1.4e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain MMR_HSR1 PF01926.18 OAJ19933.1 - 0.0039 17.1 0.6 0.026 14.4 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 OAJ19933.1 - 0.077 13.4 0.0 0.25 11.8 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein PUF PF00806.14 OAJ19934.1 - 5.3e-59 192.5 16.5 5.5e-08 31.8 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 OAJ19934.1 - 0.0082 16.4 0.1 0.87 9.8 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function DUF260 Cys_rich_CPCC PF14206.1 OAJ19935.1 - 0.14 11.7 2.5 0.19 11.2 1.8 1.3 1 0 0 1 1 1 0 Cysteine-rich CPCC HEAT_2 PF13646.1 OAJ19937.1 - 0.00018 21.6 26.8 0.067 13.4 0.0 8.3 8 2 1 9 9 9 3 HEAT repeats HEAT_EZ PF13513.1 OAJ19937.1 - 0.00048 20.5 20.5 0.7 10.4 0.2 8.0 6 1 1 7 7 7 2 HEAT-like repeat HEAT PF02985.17 OAJ19937.1 - 0.0014 18.5 24.5 0.13 12.4 0.1 9.4 11 0 0 11 11 11 2 HEAT repeat Arm PF00514.18 OAJ19937.1 - 0.0041 16.9 2.5 0.027 14.2 0.1 3.9 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat CoaE PF01121.15 OAJ19938.1 - 2e-58 196.7 0.0 3.2e-58 196.0 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 OAJ19938.1 - 1.1e-06 29.4 0.0 2.2e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ19938.1 - 0.0016 18.7 0.1 0.0057 16.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 OAJ19938.1 - 0.0034 17.2 0.0 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.1 OAJ19938.1 - 0.0046 16.8 0.8 0.021 14.7 0.0 2.4 4 0 0 4 4 4 1 AAA domain Cytidylate_kin2 PF13189.1 OAJ19938.1 - 0.093 12.6 0.0 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase-like family WW PF00397.21 OAJ19939.1 - 0.0026 17.5 0.5 0.0056 16.5 0.3 1.6 1 0 0 1 1 1 1 WW domain RhoGEF PF00621.15 OAJ19940.1 - 7.6e-17 61.7 0.0 1.4e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Hydrolase PF00702.21 OAJ19941.1 - 9.8e-23 81.6 0.0 1e-21 78.3 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 OAJ19941.1 - 8e-20 70.8 0.0 1.8e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 OAJ19941.1 - 1.2e-19 71.2 0.0 2.3e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ19941.1 - 0.00089 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAJ19941.1 - 0.0032 17.0 0.0 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 OAJ19941.1 - 0.061 12.6 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase IPP-2 PF04979.9 OAJ19943.1 - 5.5e-10 39.5 11.0 0.00037 20.7 0.0 2.5 2 1 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) IFT57 PF10498.4 OAJ19943.1 - 6.4 5.4 6.8 9.3 4.8 4.7 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Abhydrolase_6 PF12697.2 OAJ19977.1 - 5.2e-29 101.7 0.1 7.2e-29 101.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ19977.1 - 6.5e-17 61.8 0.0 1.3e-15 57.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ19977.1 - 3.3e-11 43.1 0.0 5.2e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAJ19977.1 - 0.0039 16.6 0.0 0.0053 16.2 0.0 1.3 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 OAJ19977.1 - 0.0055 16.1 0.0 0.14 11.5 0.0 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 OAJ19977.1 - 0.028 14.2 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase FSH1 PF03959.8 OAJ19977.1 - 0.05 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Thioesterase PF00975.15 OAJ19977.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 OAJ19977.1 - 0.14 11.7 0.1 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.13 OAJ19977.1 - 0.16 11.1 0.0 6.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family SDA1 PF05285.7 OAJ19978.1 - 0.00037 19.8 9.5 0.00041 19.7 6.6 1.2 1 0 0 1 1 1 1 SDA1 Daxx PF03344.10 OAJ19978.1 - 0.0032 16.0 14.0 0.0035 15.8 9.7 1.1 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 OAJ19978.1 - 0.011 13.7 17.5 0.014 13.3 12.1 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 OAJ19978.1 - 0.093 11.7 12.4 0.1 11.6 8.6 1.1 1 0 0 1 1 1 0 BUD22 DUF1510 PF07423.6 OAJ19978.1 - 0.54 9.5 12.9 0.76 9.1 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 OAJ19978.1 - 2.1 6.3 13.3 2.5 6.0 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.1 OAJ19978.1 - 2.3 7.7 14.6 3.9 7.0 10.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pox_Ag35 PF03286.9 OAJ19978.1 - 2.5 7.5 8.4 4.6 6.7 5.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein eIF-3c_N PF05470.7 OAJ19978.1 - 9.8 4.1 6.8 12 3.8 4.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus His_Phos_1 PF00300.17 OAJ19979.1 - 1.3e-40 139.0 0.0 1.5e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pol_alpha_B_N PF08418.5 OAJ19981.1 - 9.5 5.6 7.9 12 5.2 5.5 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal 3HCDH_N PF02737.13 OAJ19982.1 - 5.8e-56 188.9 1.4 1.1e-55 188.0 1.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 OAJ19982.1 - 2.2e-34 117.7 0.0 5e-34 116.5 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 OAJ19982.1 - 2.6e-05 23.9 0.6 4.7e-05 23.1 0.4 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF1188 PF06690.6 OAJ19982.1 - 0.0031 16.6 0.4 0.016 14.3 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1188) Saccharop_dh PF03435.13 OAJ19982.1 - 0.0058 15.6 0.2 0.0083 15.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 OAJ19982.1 - 0.0094 15.3 1.2 0.078 12.3 0.7 2.5 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 OAJ19982.1 - 0.047 13.5 3.1 0.23 11.3 1.7 2.3 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 OAJ19982.1 - 0.065 13.4 1.8 0.49 10.6 0.3 2.5 3 0 0 3 3 3 0 Putative NAD(P)-binding DapB_N PF01113.15 OAJ19982.1 - 0.079 12.8 2.4 0.29 11.0 0.8 2.5 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Rrf2 PF02082.15 OAJ19982.1 - 0.11 12.6 0.0 34 4.6 0.0 3.1 3 0 0 3 3 3 0 Transcriptional regulator Myc_N PF01056.13 OAJ19983.1 - 0.00062 19.0 3.5 0.00062 19.0 2.4 1.8 1 1 1 2 2 2 1 Myc amino-terminal region BRE1 PF08647.6 OAJ19983.1 - 0.022 14.7 4.1 0.95 9.4 0.3 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase HALZ PF02183.13 OAJ19983.1 - 0.053 13.2 0.5 0.093 12.4 0.3 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper START PF01852.14 OAJ19986.1 - 0.0056 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 START domain CybS PF05328.7 OAJ19987.1 - 1.2e-42 144.6 0.0 2e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 CybS DPM2 PF07297.7 OAJ19987.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Ion_trans PF00520.26 OAJ19988.1 - 5.4e-06 25.7 0.1 1e-05 24.8 0.0 1.5 2 0 0 2 2 2 1 Ion transport protein RTC4 PF14474.1 OAJ19989.1 - 3.4e-11 43.1 0.0 5.4e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain SBF PF01758.11 OAJ19989.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Sodium Bile acid symporter family Fcf2 PF08698.6 OAJ20019.1 - 5.9e-14 51.8 0.0 3.7e-13 49.3 0.0 2.2 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing SAP30_Sin3_bdg PF13867.1 OAJ20020.1 - 9.6e-08 31.7 0.0 1.1e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 CDC45 PF02724.9 OAJ20020.1 - 0.0032 15.5 2.5 0.004 15.2 1.7 1.1 1 0 0 1 1 1 1 CDC45-like protein Sporozoite_P67 PF05642.6 OAJ20020.1 - 0.012 13.4 7.7 0.017 13.0 5.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.7 OAJ20020.1 - 0.032 13.5 3.3 0.041 13.1 2.3 1.3 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 OAJ20020.1 - 0.053 12.0 2.1 0.062 11.7 1.5 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 OAJ20020.1 - 0.094 10.6 6.8 0.11 10.3 4.7 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 OAJ20020.1 - 1.4 8.7 9.6 1.3 8.7 5.4 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Prothymosin PF03247.9 OAJ20020.1 - 1.5 9.0 17.9 0.88 9.7 8.6 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family Ldh_1_N PF00056.18 OAJ20022.1 - 7.4e-44 148.9 0.1 1.1e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 OAJ20022.1 - 7.7e-42 142.9 0.0 1.2e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 OAJ20022.1 - 0.0027 16.4 0.0 0.0067 15.1 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 OAJ20022.1 - 0.0074 16.3 0.8 0.026 14.5 0.6 1.9 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 OAJ20022.1 - 0.017 15.4 0.3 0.11 12.7 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 OAJ20022.1 - 0.05 12.6 0.9 0.74 8.8 0.0 2.6 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sas10 PF09368.5 OAJ20023.1 - 2.5e-25 88.4 3.0 2.5e-25 88.4 2.1 1.8 2 0 0 2 2 2 1 Sas10 C-terminal domain TMEM171 PF15471.1 OAJ20024.1 - 0.031 13.0 0.7 0.049 12.4 0.5 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Pkinase PF00069.20 OAJ20025.1 - 6.8e-36 123.7 2.9 1.8e-24 86.3 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ20025.1 - 4.8e-27 94.6 0.0 1.7e-18 66.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase DUF4557 PF15101.1 OAJ20025.1 - 0.68 9.7 9.7 1.8 8.3 6.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF605 PF04652.11 OAJ20025.1 - 3.7 6.8 26.4 3.9 6.7 5.7 2.4 2 0 0 2 2 2 0 Vta1 like LSM PF01423.17 OAJ20026.1 - 1.6e-15 56.4 0.0 2.2e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain Glypican PF01153.14 OAJ20027.1 - 2.4 6.6 4.5 6.8 5.1 3.1 1.8 1 0 0 1 1 1 0 Glypican API5 PF05918.6 OAJ20027.1 - 6.1 5.2 12.0 0.061 11.8 1.9 2.0 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) AAA_21 PF13304.1 OAJ20028.1 - 5.4e-15 56.1 0.6 3.6e-06 27.1 0.4 2.9 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 OAJ20028.1 - 1.3e-10 41.0 0.2 1.3e-09 37.8 0.0 2.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 OAJ20028.1 - 2.9e-09 36.4 0.1 2.9e-09 36.4 0.1 3.2 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 OAJ20028.1 - 2.5e-07 30.1 38.0 0.00028 20.0 4.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_13 PF13166.1 OAJ20028.1 - 6.4e-05 21.6 0.1 6.4e-05 21.6 0.1 8.0 3 1 2 7 7 6 5 AAA domain AAA_29 PF13555.1 OAJ20028.1 - 0.00019 20.9 0.0 0.00037 19.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 OAJ20028.1 - 0.0013 19.0 0.0 0.0013 19.0 0.0 7.1 3 2 1 5 5 3 1 ABC transporter AAA_23 PF13476.1 OAJ20028.1 - 0.0037 17.6 143.3 1.5e+04 -13.9 76.9 8.5 1 1 1 2 2 0 0 AAA domain AAA_19 PF13245.1 OAJ20028.1 - 0.022 14.5 0.4 0.13 12.0 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain Miro PF08477.8 OAJ20028.1 - 0.028 14.9 1.2 0.59 10.6 0.0 3.7 3 0 0 3 3 3 0 Miro-like protein DUF1829 PF08862.5 OAJ20028.1 - 0.073 13.3 0.1 0.073 13.3 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function DUF1829 DUF2839 PF10999.3 OAJ20029.1 - 0.096 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) Sas10 PF09368.5 OAJ20030.1 - 6e-25 87.2 3.0 1.8e-24 85.6 2.1 1.9 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 OAJ20030.1 - 3.7e-09 36.6 0.0 1.4e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Pkinase PF00069.20 OAJ20031.1 - 3.6e-70 236.0 0.0 4.5e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ20031.1 - 1.2e-29 103.2 0.0 1.6e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ20031.1 - 0.029 14.0 0.1 0.029 14.0 0.0 2.9 2 2 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 OAJ20031.1 - 0.92 8.5 4.0 0.47 9.4 0.1 2.3 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Esterase PF00756.15 OAJ20061.1 - 1.6e-05 24.4 0.0 3.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 OAJ20061.1 - 0.00028 20.6 0.0 0.00094 18.9 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ20061.1 - 0.0025 17.7 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DNA_pol_viral_C PF00336.13 OAJ20062.1 - 0.1 11.8 0.1 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Phage_integrase PF00589.17 OAJ20066.1 - 0.0043 16.7 0.0 0.0082 15.8 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family UPF0086 PF01868.11 OAJ20067.1 - 5.3e-12 45.2 0.0 1.6e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function UPF0086 Sdh5 PF03937.11 OAJ20068.1 - 1.4e-22 79.1 0.3 8.9e-22 76.5 0.1 2.1 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase Pterin_4a PF01329.14 OAJ20069.1 - 9.8e-26 89.3 0.2 1.2e-25 89.0 0.1 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase KSHV_K8 PF07188.6 OAJ20069.1 - 0.066 12.4 0.1 0.066 12.4 0.1 1.1 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein GIY-YIG PF01541.19 OAJ20070.1 - 3.7e-05 24.0 0.0 0.00027 21.2 0.0 2.4 3 0 0 3 3 3 1 GIY-YIG catalytic domain Tmemb_55A PF09788.4 OAJ20070.1 - 0.038 13.1 0.1 0.084 11.9 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 55A 4HBT_3 PF13622.1 OAJ20071.1 - 6.7e-25 88.2 2.8 9.1e-25 87.8 2.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 OAJ20071.1 - 0.00066 19.3 0.1 0.002 17.7 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA thioesterase Cyclin PF08613.6 OAJ20072.1 - 1.1e-10 42.1 0.0 2.5e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Cyclin DUF1604 PF07713.8 OAJ20073.1 - 1.2e-32 111.5 9.2 1e-29 102.1 6.4 2.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 OAJ20073.1 - 3.7e-05 23.4 0.4 0.00015 21.4 0.0 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 OAJ20073.1 - 0.0088 15.8 4.5 0.011 15.5 0.0 3.2 3 0 0 3 3 3 1 DExH-box splicing factor binding site GPI-anchored PF10342.4 OAJ20074.1 - 4.5e-06 27.0 0.0 9.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Sld5 PF05916.6 OAJ20075.1 - 0.00013 22.1 1.8 0.00015 21.9 0.0 1.9 2 0 0 2 2 2 1 GINS complex protein WD40 PF00400.27 OAJ20076.1 - 0.28 11.1 2.5 25 4.9 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat DDE_Tnp_4 PF13359.1 OAJ20077.1 - 0.00024 20.7 0.0 0.00028 20.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease BUD22 PF09073.5 OAJ20078.1 - 0.2 10.6 2.1 0.27 10.2 1.5 1.1 1 0 0 1 1 1 0 BUD22 MIS13 PF08202.6 OAJ20113.1 - 1.3e-17 63.8 0.0 1.5e-14 53.8 0.1 3.4 2 1 0 2 2 2 2 Mis12-Mtw1 protein family Mito_carr PF00153.22 OAJ20114.1 - 1.6e-15 56.5 3.2 2.3e-05 24.0 0.0 5.7 6 0 0 6 6 6 5 Mitochondrial carrier protein Phytase-like PF13449.1 OAJ20115.1 - 1e-25 90.7 0.1 2.2e-25 89.6 0.0 1.5 1 1 0 1 1 1 1 Esterase-like activity of phytase HEAT_EZ PF13513.1 OAJ20116.1 - 3.6e-20 71.8 21.3 3.7e-09 36.8 0.0 10.3 10 1 1 11 11 11 3 HEAT-like repeat HEAT_2 PF13646.1 OAJ20116.1 - 2.3e-18 66.2 8.2 1.2e-06 28.6 0.0 7.3 4 3 5 9 9 9 6 HEAT repeats HEAT PF02985.17 OAJ20116.1 - 2.5e-18 64.4 13.9 0.0019 18.1 0.0 9.8 10 0 0 10 10 10 4 HEAT repeat Vac14_Fab1_bd PF12755.2 OAJ20116.1 - 1.6e-11 44.4 0.0 0.0022 18.3 0.0 5.3 3 2 1 4 4 4 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 OAJ20116.1 - 1.1e-05 24.3 8.6 0.011 14.5 0.0 4.1 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal IBN_N PF03810.14 OAJ20116.1 - 1.2e-05 25.1 0.1 6.5e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cnd1 PF12717.2 OAJ20116.1 - 1.5e-05 24.9 0.0 0.0054 16.5 0.0 4.0 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 OAJ20116.1 - 2.1e-05 24.1 8.2 0.5 10.2 0.0 6.2 7 0 0 7 7 6 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 OAJ20116.1 - 0.0012 17.2 0.3 0.0042 15.4 0.1 1.9 2 0 0 2 2 2 1 Adaptin N terminal region ParcG PF10274.4 OAJ20116.1 - 0.0021 17.9 0.1 2.3 8.0 0.0 3.4 2 1 1 3 3 3 1 Parkin co-regulated protein DUF2435 PF10363.4 OAJ20116.1 - 0.0028 17.5 0.2 0.023 14.5 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) CLASP_N PF12348.3 OAJ20116.1 - 0.031 13.6 0.2 4.3 6.6 0.1 4.0 3 2 1 4 4 4 0 CLASP N terminal DARPP-32 PF05395.7 OAJ20116.1 - 0.046 13.8 0.2 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Proteasom_PSMB PF10508.4 OAJ20116.1 - 0.081 11.1 0.0 0.58 8.3 0.0 2.2 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit RNA_pol_3_Rpc31 PF11705.3 OAJ20116.1 - 0.082 12.8 9.2 0.14 12.1 6.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RPAP3_C PF13877.1 OAJ20116.1 - 0.086 12.8 0.0 0.39 10.7 0.0 2.2 2 0 0 2 2 1 0 Potential Monad-binding region of RPAP3 DUF3437 PF11919.3 OAJ20116.1 - 0.14 11.9 0.0 19 5.0 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Cnd3 PF12719.2 OAJ20116.1 - 0.35 9.8 1.4 1.8 7.4 0.0 2.7 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain TRM PF02005.11 OAJ20117.1 - 4.5e-115 384.5 0.0 1.1e-86 291.1 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase DUF3138 PF11336.3 OAJ20117.1 - 0.21 9.6 6.2 0.37 8.9 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FAD_binding_8 PF08022.7 OAJ20118.1 - 2.5e-16 59.4 0.0 2.5e-10 40.1 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain Ferric_reduct PF01794.14 OAJ20118.1 - 8.8e-14 51.6 14.6 8.8e-14 51.6 10.1 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 OAJ20118.1 - 1.8e-11 44.2 0.0 5.7e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Esterase PF00756.15 OAJ20119.1 - 6.1e-36 124.1 0.0 8.4e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 OAJ20119.1 - 8.8e-06 25.5 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 OAJ20119.1 - 0.08 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Gti1_Pac2 PF09729.4 OAJ20120.1 - 1.3e-34 119.5 20.4 3.1e-29 102.0 0.8 5.3 3 1 1 4 4 4 2 Gti1/Pac2 family AIF_C PF14721.1 OAJ20120.1 - 0.18 12.0 0.1 0.18 12.0 0.1 3.4 4 0 0 4 4 4 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Ric8 PF10165.4 OAJ20122.1 - 9.9e-55 186.1 6.5 8.4e-39 133.6 0.0 3.4 3 0 0 3 3 3 3 Guanine nucleotide exchange factor synembryn Gly-zipper_OmpA PF13436.1 OAJ20155.1 - 0.0039 16.8 0.6 0.0062 16.1 0.4 1.4 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain PRP1_N PF06424.7 OAJ20155.1 - 0.1 12.9 0.2 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Tom5 PF10642.4 OAJ20155.1 - 0.96 9.1 4.9 0.22 11.1 0.6 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase zf-C2H2_4 PF13894.1 OAJ20156.1 - 0.5 10.8 0.1 0.5 10.8 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 OAJ20156.1 - 0.61 10.5 0.0 0.61 10.5 0.0 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type NIF PF03031.13 OAJ20157.1 - 9.8e-38 129.3 0.0 1.4e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Acyltransferase PF01553.16 OAJ20157.1 - 2.3e-22 78.8 0.0 3.5e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase HORMA PF02301.13 OAJ20158.1 - 4.9e-39 133.9 0.0 5.6e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 HORMA domain FlaG PF03646.10 OAJ20158.1 - 0.056 13.5 0.0 7.8 6.6 0.0 2.3 2 0 0 2 2 2 0 FlaG protein AAA_22 PF13401.1 OAJ20159.1 - 2.5e-10 40.5 0.0 9.8e-10 38.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ20159.1 - 8e-07 29.2 0.0 2.5e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 OAJ20159.1 - 4e-06 27.0 0.5 0.005 17.0 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 OAJ20159.1 - 0.0075 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 OAJ20159.1 - 0.014 15.0 0.1 0.1 12.2 0.1 2.3 1 1 0 1 1 1 0 NACHT domain PIF1 PF05970.9 OAJ20159.1 - 0.093 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase tRNA-synt_2b PF00587.20 OAJ20161.1 - 6.8e-43 146.2 0.0 1.1e-42 145.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ20161.1 - 1.6e-11 43.9 0.1 1.4e-08 34.5 0.0 2.3 2 0 0 2 2 2 2 Anticodon binding domain DEAD PF00270.24 OAJ20162.1 - 1.2e-06 28.0 0.0 5.3e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ20162.1 - 0.0015 18.3 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 OAJ20162.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain Flag1_repress PF03614.8 OAJ20163.1 - 0.14 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Repressor of phase-1 flagellin DUF3632 PF12311.3 OAJ20164.1 - 0.046 13.5 0.8 8 6.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3632) Det1 PF09737.4 OAJ20164.1 - 0.5 9.0 0.6 0.8 8.4 0.4 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 TRAP_alpha PF03896.11 OAJ20165.1 - 0.0081 15.1 0.4 0.08 11.9 0.0 2.2 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit Sugar_tr PF00083.19 OAJ20165.1 - 0.01 14.4 2.9 0.065 11.8 0.0 3.3 3 1 1 4 4 4 0 Sugar (and other) transporter FAM176 PF14851.1 OAJ20165.1 - 0.18 11.5 0.7 4.3 6.9 0.1 3.0 3 0 0 3 3 3 0 FAM176 family Sigma70_ner PF04546.8 OAJ20165.1 - 1.1 8.8 10.8 0.18 11.3 1.7 2.6 3 0 0 3 3 3 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 OAJ20165.1 - 4.9 6.6 11.5 2.4 7.6 4.5 2.3 2 0 0 2 2 2 0 Nucleoplasmin VID27 PF08553.5 OAJ20165.1 - 6.7 4.8 5.3 11 4.0 3.7 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein UbiA PF01040.13 OAJ20166.1 - 1.9e-22 79.7 27.7 3.9e-22 78.7 19.2 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family Glucosamine_iso PF01182.15 OAJ20167.1 - 8.2e-67 224.7 0.0 9.5e-67 224.5 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF202 PF02656.10 OAJ20168.1 - 7.1e-05 22.9 4.7 0.00024 21.2 2.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Pex14_N PF04695.8 OAJ20168.1 - 0.0014 18.6 3.3 0.045 13.8 0.1 2.2 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_E56 PF04639.7 OAJ20168.1 - 0.039 12.6 0.1 0.068 11.8 0.0 1.3 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope Shisa PF13908.1 OAJ20168.1 - 0.093 12.9 9.2 0.38 10.9 0.1 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Ctr PF04145.10 OAJ20168.1 - 0.13 12.3 0.4 0.6 10.1 0.0 2.0 2 0 0 2 2 2 0 Ctr copper transporter family Chitin_synth_2 PF03142.10 OAJ20169.1 - 8.6e-234 776.8 0.0 1.2e-233 776.3 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 OAJ20169.1 - 6e-14 52.1 9.9 6e-14 52.1 6.9 2.8 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ20169.1 - 6e-13 49.1 0.1 1.7e-11 44.3 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 OAJ20169.1 - 0.0022 17.7 0.1 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 OAJ20169.1 - 0.047 13.3 0.0 0.92 9.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 GMC_oxred_N PF00732.14 OAJ20199.1 - 6.3e-60 202.8 0.0 8.2e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ20199.1 - 3.3e-29 102.0 0.0 6.5e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAJ20199.1 - 2e-08 33.5 0.3 1.1e-05 24.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ20199.1 - 1.2e-06 28.4 0.0 1.8e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAJ20199.1 - 1.3e-05 24.2 0.0 9.7e-05 21.3 0.0 2.1 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 OAJ20199.1 - 1.8e-05 24.9 0.0 0.0013 18.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAJ20199.1 - 4.2e-05 22.6 0.1 0.0001 21.3 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 OAJ20199.1 - 0.0027 16.8 0.1 0.0055 15.8 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 OAJ20199.1 - 0.0041 17.0 0.0 0.022 14.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 OAJ20199.1 - 0.064 11.8 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 OAJ20199.1 - 0.066 11.6 0.4 0.16 10.3 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 OAJ20199.1 - 0.083 12.6 0.1 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Alpha_GJ PF03229.8 OAJ20199.1 - 6.8 7.0 16.3 5.9 7.2 2.3 2.6 2 0 0 2 2 2 0 Alphavirus glycoprotein J Iso_dh PF00180.15 OAJ20200.1 - 1.7e-101 339.6 0.0 2.2e-101 339.3 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PhzC-PhzF PF02567.11 OAJ20201.1 - 2.7e-39 135.0 0.0 3.3e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 OAJ20201.1 - 0.0023 16.8 0.0 0.0036 16.1 0.0 1.2 1 0 0 1 1 1 1 Proline racemase Fungal_trans PF04082.13 OAJ20202.1 - 2.9e-11 42.7 0.1 4.6e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ20202.1 - 3.5e-07 30.0 10.0 5.7e-07 29.3 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.14 OAJ20202.1 - 0.26 11.6 6.1 0.82 10.1 4.2 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein HSP70 PF00012.15 OAJ20204.1 - 1.6e-260 865.2 14.3 1.8e-260 865.0 9.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAJ20204.1 - 4.7e-19 68.1 0.4 4.1e-17 61.7 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.5 OAJ20204.1 - 0.00012 21.0 1.0 0.0086 14.9 0.2 2.5 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 OAJ20204.1 - 0.02 14.5 0.0 0.066 12.8 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain RasGAP PF00616.14 OAJ20204.1 - 0.1 12.2 0.6 0.22 11.1 0.4 1.5 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase FtsA PF14450.1 OAJ20204.1 - 0.11 12.3 5.7 1 9.2 1.2 4.0 2 1 0 2 2 2 0 Cell division protein FtsA CENP-I PF07778.6 OAJ20204.1 - 0.51 8.4 2.5 3.1 5.8 0.5 2.1 2 0 0 2 2 2 0 Mis6 Hydantoinase_A PF01968.13 OAJ20204.1 - 0.89 8.5 7.6 0.26 10.3 0.3 3.2 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase Seryl_tRNA_N PF02403.17 OAJ20204.1 - 1.1 9.2 13.2 3.8 7.5 4.4 3.2 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain AAA_23 PF13476.1 OAJ20204.1 - 1.3 9.3 9.5 0.23 11.7 3.4 2.0 2 0 0 2 2 2 0 AAA domain Spectrin PF00435.16 OAJ20204.1 - 2.2 8.5 7.9 18 5.7 0.9 2.7 1 1 1 2 2 2 0 Spectrin repeat Uds1 PF15456.1 OAJ20204.1 - 2.7 8.0 7.0 0.72 9.8 1.4 2.1 2 0 0 2 2 2 0 Up-regulated During Septation DUF4600 PF15372.1 OAJ20205.1 - 0.0054 16.9 4.0 0.014 15.6 0.6 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4600) MEDS PF14417.1 OAJ20205.1 - 0.095 11.7 1.8 0.18 10.8 1.3 1.3 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Bromodomain PF00439.20 OAJ20206.1 - 1.3e-30 105.0 1.8 1.1e-14 54.0 0.1 3.8 3 1 0 3 3 3 2 Bromodomain Abhydro_lipase PF04083.11 OAJ20207.1 - 2.5e-14 52.3 0.0 4.7e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 OAJ20207.1 - 6.9e-06 25.8 0.0 9.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ20207.1 - 0.014 14.9 0.1 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold F-box-like PF12937.2 OAJ20208.1 - 6.4e-09 35.3 1.8 1.6e-08 34.1 1.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ20208.1 - 3.5e-07 29.7 1.3 6e-07 28.9 0.9 1.4 1 0 0 1 1 1 1 F-box domain CD99L2 PF12301.3 OAJ20208.1 - 0.85 9.2 8.4 0.03 14.0 1.0 1.9 2 0 0 2 2 2 0 CD99 antigen like protein 2 HsbA PF12296.3 OAJ20209.1 - 2.6e-16 59.6 13.0 4.1e-16 58.9 9.0 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A ALS_ss_C PF10369.4 OAJ20209.1 - 0.02 14.6 0.2 0.23 11.2 0.1 2.2 1 1 1 2 2 2 0 Small subunit of acetolactate synthase Baculo_PEP_C PF04513.7 OAJ20209.1 - 0.17 11.6 7.6 0.21 11.3 5.1 1.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUN14 PF04930.10 OAJ20209.1 - 0.54 10.5 3.6 1.1 9.5 0.9 2.3 1 1 0 2 2 2 0 FUN14 family Ribosomal_L22 PF00237.14 OAJ20209.1 - 0.84 9.6 3.3 2.4 8.1 2.3 2.0 1 1 0 1 1 1 0 Ribosomal protein L22p/L17e RRM_6 PF14259.1 OAJ20242.1 - 0.00018 21.4 0.0 0.0011 18.8 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ20242.1 - 0.00092 18.8 0.0 0.23 11.1 0.0 3.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 OAJ20242.1 - 0.49 8.2 33.2 0.0084 14.1 7.9 2.0 2 0 0 2 2 2 0 Nop14-like family RhoGEF PF00621.15 OAJ20243.1 - 3.7e-12 46.5 0.0 2.7e-08 33.9 0.0 2.5 2 1 0 2 2 2 2 RhoGEF domain PH PF00169.24 OAJ20243.1 - 0.00022 21.3 0.0 0.00041 20.5 0.0 1.4 1 0 0 1 1 1 1 PH domain Sulfate_transp PF00916.15 OAJ20245.1 - 8.6e-21 74.1 1.6 1.6e-20 73.3 1.1 1.4 1 0 0 1 1 1 1 Sulfate transporter family Complex1_LYR_1 PF13232.1 OAJ20247.1 - 1.1e-13 51.1 0.0 1.8e-13 50.5 0.0 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 OAJ20247.1 - 9.8e-07 28.4 6.4 2e-06 27.5 4.4 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) XS PF03468.9 OAJ20248.1 - 0.053 13.4 0.0 0.061 13.2 0.0 1.1 1 0 0 1 1 1 0 XS domain UPF0052 PF01933.13 OAJ20249.1 - 7.4e-38 130.5 0.0 1.1e-25 90.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family UPF0052 GST_C_3 PF14497.1 OAJ20250.1 - 1.6e-08 34.9 0.0 2.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAJ20250.1 - 2.8e-07 30.4 0.0 4.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ20250.1 - 0.0013 18.5 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CNH PF00780.17 OAJ20251.1 - 0.48 9.7 0.0 31 3.8 0.0 2.2 2 0 0 2 2 2 0 CNH domain cNMP_binding PF00027.24 OAJ20252.1 - 1e-12 47.6 0.0 2.1e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Sulfate_transp PF00916.15 OAJ20252.1 - 4e-12 45.7 0.2 7.2e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 OAJ20252.1 - 1.9e-10 40.1 0.1 4.2e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 STAS domain DUF1985 PF09331.6 OAJ20252.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) TM_helix PF05552.7 OAJ20252.1 - 8.2 6.1 8.5 0.7 9.6 1.0 2.5 2 0 0 2 2 2 0 Conserved TM helix Cullin PF00888.17 OAJ20287.1 - 5.2e-24 84.7 0.0 3e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 Cullin family FeoC PF09012.5 OAJ20287.1 - 0.092 12.4 0.0 0.28 10.8 0.0 1.8 1 0 0 1 1 1 0 FeoC like transcriptional regulator SYF2 PF08231.7 OAJ20288.1 - 2e-41 141.6 5.5 2e-41 141.6 3.8 1.9 2 0 0 2 2 2 1 SYF2 splicing factor WD40 PF00400.27 OAJ20288.1 - 0.02 14.7 0.0 1.4 8.9 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat DivIC PF04977.10 OAJ20289.1 - 0.36 10.3 2.2 2 7.9 1.5 2.1 2 0 0 2 2 2 0 Septum formation initiator COQ7 PF03232.8 OAJ20290.1 - 7e-61 204.6 0.0 9.5e-61 204.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Pex14_N PF04695.8 OAJ20290.1 - 9.4 6.2 8.4 83 3.2 4.1 2.3 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Prenyltrans PF00432.16 OAJ20291.1 - 2.2e-29 100.6 11.0 1.1e-07 31.3 0.0 5.6 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 OAJ20291.1 - 1.5e-16 60.7 0.0 2.2e-14 53.8 0.0 3.4 3 0 0 3 3 3 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 OAJ20291.1 - 0.0011 18.9 0.0 0.0095 15.9 0.0 2.4 1 1 1 2 2 2 2 Prenyltransferase-like Response_reg PF00072.19 OAJ20292.1 - 1.5e-06 28.1 0.0 0.0001 22.2 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain MRP-L46 PF11788.3 OAJ20293.1 - 6.7e-18 65.3 0.2 2.4e-17 63.5 0.0 2.1 2 1 0 2 2 2 1 39S mitochondrial ribosomal protein L46 Tautomerase PF01361.16 OAJ20293.1 - 0.34 10.5 1.3 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Tautomerase enzyme Symplekin_C PF12295.3 OAJ20294.1 - 5.9e-52 176.2 0.1 1.9e-51 174.5 0.0 1.9 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 OAJ20294.1 - 2.2e-33 115.6 0.1 4.4e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) HEAT_EZ PF13513.1 OAJ20294.1 - 0.0058 17.0 0.4 0.05 14.1 0.1 2.9 2 0 0 2 2 2 1 HEAT-like repeat zf-H2C2_2 PF13465.1 OAJ20296.1 - 5.9e-08 32.6 0.3 5.9e-08 32.6 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ20296.1 - 5e-05 23.4 13.3 0.0002 21.4 0.6 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ20296.1 - 0.00011 22.2 1.0 0.00011 22.2 0.7 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 OAJ20296.1 - 0.059 13.3 3.8 0.12 12.3 0.3 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger SPRR2 PF14820.1 OAJ20296.1 - 1.8 8.5 10.2 0.8 9.6 3.8 2.4 2 0 0 2 2 2 0 Small proline-rich 2 DUF1746 PF08508.5 OAJ20297.1 - 3.4e-12 46.3 4.4 2.8e-11 43.3 3.0 2.1 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) DIOX_N PF14226.1 OAJ20298.1 - 2.4e-20 73.2 0.0 3.5e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAJ20298.1 - 4.3e-17 62.2 0.0 7.2e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC_tran PF00005.22 OAJ20299.1 - 5.6e-43 146.5 0.0 1e-20 74.4 0.0 3.1 2 1 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 OAJ20299.1 - 3.6e-23 81.2 2.1 3.6e-23 81.2 1.5 2.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 OAJ20299.1 - 1e-15 58.5 0.1 0.00017 21.6 0.0 4.4 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 OAJ20299.1 - 6.6e-13 48.4 0.1 8.3e-06 25.1 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 OAJ20299.1 - 2.1e-08 33.9 0.7 0.03 13.7 0.0 4.4 4 0 0 4 4 4 2 AAA-like domain AAA_22 PF13401.1 OAJ20299.1 - 2.7e-07 30.7 0.4 0.013 15.6 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 OAJ20299.1 - 4.9e-07 30.6 0.6 0.012 16.3 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 OAJ20299.1 - 6.5e-07 28.7 0.1 0.005 16.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 OAJ20299.1 - 1.1e-05 25.3 0.1 0.016 15.1 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase Miro PF08477.8 OAJ20299.1 - 1.3e-05 25.6 0.0 0.22 12.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 OAJ20299.1 - 5.2e-05 22.8 0.0 0.19 11.1 0.0 2.7 2 0 0 2 2 2 2 FtsK/SpoIIIE family NACHT PF05729.7 OAJ20299.1 - 6.5e-05 22.6 0.0 0.12 12.0 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.1 OAJ20299.1 - 0.00026 21.0 0.1 0.96 9.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 OAJ20299.1 - 0.00026 20.8 2.8 0.033 13.9 0.0 3.5 3 1 0 3 3 3 1 Domain of unknown function DUF87 AAA_33 PF13671.1 OAJ20299.1 - 0.00042 20.2 0.7 0.75 9.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 OAJ20299.1 - 0.00059 19.5 0.0 0.25 11.0 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 OAJ20299.1 - 0.00064 19.5 0.1 0.17 11.8 0.1 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 OAJ20299.1 - 0.00065 18.9 0.0 0.19 10.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 OAJ20299.1 - 0.00074 19.6 0.0 0.063 13.4 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 OAJ20299.1 - 0.00082 19.2 0.0 1.3 8.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 OAJ20299.1 - 0.0011 18.3 0.1 0.32 10.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 OAJ20299.1 - 0.0027 18.0 7.0 0.15 12.3 0.0 3.7 4 0 0 4 4 4 1 AAA domain T2SE PF00437.15 OAJ20299.1 - 0.0065 15.4 0.0 0.16 10.8 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein ArgK PF03308.11 OAJ20299.1 - 0.0085 14.8 0.0 1.3 7.7 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_16 PF13191.1 OAJ20299.1 - 0.0088 16.0 7.8 0.59 10.1 0.2 3.7 5 1 0 5 5 3 2 AAA ATPase domain AAA_15 PF13175.1 OAJ20299.1 - 0.012 14.6 0.9 4.9 6.0 0.0 3.4 4 0 0 4 4 4 0 AAA ATPase domain GTP_EFTU PF00009.22 OAJ20299.1 - 0.016 14.6 0.0 0.33 10.3 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MutS_V PF00488.16 OAJ20299.1 - 0.018 14.4 0.0 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 MutS domain V AAA_18 PF13238.1 OAJ20299.1 - 0.02 15.1 0.1 2.1 8.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain DUF287 PF03384.9 OAJ20299.1 - 0.035 14.2 0.3 0.16 12.1 0.1 2.2 2 0 0 2 2 1 0 Drosophila protein of unknown function, DUF287 cobW PF02492.14 OAJ20299.1 - 0.051 13.0 0.1 8.4 5.7 0.0 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 OAJ20299.1 - 0.098 12.4 4.6 0.76 9.5 0.0 3.2 4 0 0 4 4 3 0 Dynamin family Arch_ATPase PF01637.13 OAJ20299.1 - 0.16 11.6 3.8 6.1 6.4 0.0 3.2 4 0 0 4 4 3 0 Archaeal ATPase TFIID_30kDa PF03540.8 OAJ20329.1 - 7.7e-26 89.6 0.0 1.3e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CBS PF00571.23 OAJ20329.1 - 4.2e-05 23.2 0.1 0.0077 16.0 0.1 2.5 2 0 0 2 2 2 2 CBS domain Ribosomal_60s PF00428.14 OAJ20329.1 - 0.42 11.0 0.1 0.42 11.0 0.1 3.2 4 0 0 4 4 4 0 60s Acidic ribosomal protein FoP_duplication PF13865.1 OAJ20329.1 - 2.8 8.4 4.4 1.3 9.5 0.2 2.4 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 PAXIP1_C PF15364.1 OAJ20330.1 - 7.8 6.4 10.1 0.11 12.3 1.4 2.0 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein PGK PF00162.14 OAJ20332.1 - 3.2e-150 499.9 2.9 3.7e-150 499.7 2.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase NTF2 PF02136.15 OAJ20333.1 - 8e-34 116.5 0.2 9.7e-34 116.2 0.1 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Glutaredoxin PF00462.19 OAJ20334.1 - 6.4e-19 67.7 0.0 1e-17 63.8 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 OAJ20334.1 - 2.8e-17 62.2 0.0 5e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 OAJ20334.1 - 1.2e-05 25.2 0.1 0.0069 16.4 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ20334.1 - 0.0021 18.2 0.0 0.011 15.8 0.0 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.6 OAJ20334.1 - 0.0066 16.3 0.0 0.033 14.0 0.0 2.1 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE GST_N_3 PF13417.1 OAJ20334.1 - 0.076 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ArsC PF03960.10 OAJ20334.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 ArsC family HMG_box PF00505.14 OAJ20335.1 - 3.3e-10 40.0 1.1 6.2e-10 39.2 0.8 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 OAJ20335.1 - 0.00014 21.2 0.2 0.00025 20.4 0.1 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 TPT PF03151.11 OAJ20336.1 - 1.7e-31 108.9 7.5 1.7e-31 108.9 5.2 2.2 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 OAJ20336.1 - 2.3e-10 40.6 22.3 1e-05 25.5 4.9 2.5 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 OAJ20336.1 - 5.4e-08 32.1 14.4 1.3e-07 30.8 10.0 1.5 1 1 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.14 OAJ20336.1 - 0.37 11.3 10.0 0.035 14.5 3.4 2.0 2 0 0 2 2 2 0 Small Multidrug Resistance protein A_deaminase PF00962.17 OAJ20337.1 - 2.5e-108 361.9 0.1 3.4e-108 361.4 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase 4HBT PF03061.17 OAJ20338.1 - 1.3e-06 28.4 0.0 2.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DUF1180 PF06679.7 OAJ20338.1 - 2.9 7.7 5.6 0.75 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) PX PF00787.19 OAJ20339.1 - 1e-11 44.5 0.0 2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 PX domain SpoIIIAH PF12685.2 OAJ20339.1 - 1.1 8.7 3.3 2.4 7.5 2.3 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein DEAD PF00270.24 OAJ20340.1 - 2.6e-42 144.2 0.5 5e-42 143.2 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ20340.1 - 1.6e-29 101.6 0.1 3.8e-29 100.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 OAJ20340.1 - 0.0051 16.5 0.2 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 OAJ20340.1 - 0.019 14.7 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1253 PF06862.7 OAJ20340.1 - 0.023 13.1 0.0 0.085 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_30 PF13604.1 OAJ20340.1 - 0.059 12.9 0.2 0.14 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 OAJ20340.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase zf-met PF12874.2 OAJ20341.1 - 0.00028 20.9 0.1 0.00062 19.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 OAJ20341.1 - 0.0012 18.9 0.1 0.004 17.2 0.1 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding SF3a60_bindingd PF12108.3 OAJ20341.1 - 0.0038 16.7 0.8 0.019 14.5 0.0 2.2 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain DUF3449 PF11931.3 OAJ20341.1 - 0.0058 16.1 1.3 0.11 12.0 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) DUF812 PF05667.6 OAJ20341.1 - 0.22 10.0 3.4 0.3 9.5 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) NIF PF03031.13 OAJ20342.1 - 8e-49 165.3 0.0 2.3e-42 144.3 0.0 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Spt20 PF12090.3 OAJ20342.1 - 0.23 10.7 4.0 12 5.1 0.0 2.1 2 0 0 2 2 2 0 Spt20 family Mitofilin PF09731.4 OAJ20342.1 - 0.38 9.3 7.1 0.52 8.8 4.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FLO_LFY PF01698.11 OAJ20342.1 - 0.72 8.6 9.0 1 8.1 6.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Baculo_PP31 PF05311.6 OAJ20342.1 - 0.87 8.7 5.4 1.2 8.3 3.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Daxx PF03344.10 OAJ20342.1 - 4.5 5.6 20.7 5.9 5.2 14.4 1.1 1 0 0 1 1 1 0 Daxx Family ORC6 PF05460.8 OAJ20342.1 - 5.5 5.9 14.5 6.7 5.7 10.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FAM60A PF15396.1 OAJ20342.1 - 8.5 6.0 9.2 14 5.3 6.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Homoserine_dh PF00742.14 OAJ20343.1 - 4.9e-46 156.6 0.0 7.1e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 OAJ20343.1 - 2.1e-14 53.9 0.0 4e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Evr1_Alr PF04777.8 OAJ20382.1 - 1.1e-28 98.8 0.2 1.7e-28 98.3 0.1 1.3 1 0 0 1 1 1 1 Erv1 / Alr family DUF4585 PF15232.1 OAJ20382.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) RNA_pol_Rpb1_1 PF04997.7 OAJ20383.1 - 4.1e-113 378.0 0.0 5.6e-113 377.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 OAJ20383.1 - 6.1e-104 347.1 0.1 8.7e-104 346.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 OAJ20383.1 - 8e-68 227.5 0.0 1.6e-67 226.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 OAJ20383.1 - 6.6e-61 205.3 0.2 1.1e-60 204.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 OAJ20383.1 - 2.3e-45 154.1 0.0 4.6e-45 153.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 OAJ20383.1 - 4.4e-42 142.9 0.5 9.3e-42 141.9 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 OAJ20383.1 - 2e-36 123.9 0.1 4.7e-36 122.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 OAJ20383.1 - 3.9e-19 66.9 234.9 0.017 15.1 6.6 15.5 10 1 6 18 18 18 17 RNA polymerase Rpb1 C-terminal repeat PCI PF01399.22 OAJ20384.1 - 7.8e-20 71.1 0.0 2.1e-19 69.7 0.0 1.8 1 0 0 1 1 1 1 PCI domain HTH_27 PF13463.1 OAJ20384.1 - 0.0079 16.4 0.0 0.026 14.8 0.0 1.9 1 0 0 1 1 1 1 Winged helix DNA-binding domain TPR_14 PF13428.1 OAJ20384.1 - 0.086 13.5 3.6 5.3 7.9 1.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ20384.1 - 0.19 11.8 2.6 1 9.4 0.8 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ20384.1 - 0.39 11.0 3.3 6.5 7.1 0.9 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ20384.1 - 0.42 11.1 3.6 15 6.3 1.5 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RrnaAD PF00398.15 OAJ20385.1 - 6.7e-17 61.3 0.0 2e-16 59.8 0.0 1.7 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase AT_hook PF02178.14 OAJ20385.1 - 0.0082 15.7 16.7 0.11 12.2 2.8 2.7 2 0 0 2 2 2 2 AT hook motif ABC_tran PF00005.22 OAJ20386.1 - 7.6e-36 123.4 0.1 6.8e-18 65.2 0.0 3.1 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 OAJ20386.1 - 8.8e-15 54.0 5.8 2.2e-14 52.7 4.0 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 OAJ20386.1 - 3.9e-14 53.3 5.7 8.4e-05 22.6 0.9 4.2 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 OAJ20386.1 - 1.1e-09 37.8 4.9 0.00059 19.1 0.5 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 OAJ20386.1 - 2.2e-07 30.1 3.3 2.2e-07 30.1 2.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.1 OAJ20386.1 - 1.5e-06 27.5 0.2 4.1 6.3 0.0 4.4 5 0 0 5 5 4 0 AAA ATPase domain DUF258 PF03193.11 OAJ20386.1 - 5.2e-06 25.7 0.8 0.12 11.5 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 OAJ20386.1 - 6.8e-06 26.2 0.2 0.0044 17.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 OAJ20386.1 - 8e-06 26.0 0.0 0.032 14.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 OAJ20386.1 - 1.4e-05 24.4 0.2 0.039 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain VirE PF05272.6 OAJ20386.1 - 7.3e-05 22.3 0.0 0.41 10.0 0.0 2.4 2 0 0 2 2 2 2 Virulence-associated protein E Fer4_6 PF12837.2 OAJ20386.1 - 8.2e-05 22.3 2.4 8.2e-05 22.3 1.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.2 OAJ20386.1 - 0.0001 22.5 8.4 0.00049 20.4 0.2 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_23 PF13476.1 OAJ20386.1 - 0.00025 21.4 4.9 0.0056 17.0 0.2 2.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 OAJ20386.1 - 0.00027 20.6 1.3 0.031 13.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 OAJ20386.1 - 0.00034 21.0 0.4 0.54 10.7 0.0 3.0 2 1 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 OAJ20386.1 - 0.0004 20.4 0.0 0.058 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 OAJ20386.1 - 0.00047 19.6 0.1 0.39 10.1 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 OAJ20386.1 - 0.00067 19.5 0.2 0.12 12.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 OAJ20386.1 - 0.00072 19.8 0.3 0.51 10.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 OAJ20386.1 - 0.00088 19.1 0.0 1.3 9.0 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 OAJ20386.1 - 0.00095 19.9 2.9 1.2 9.9 0.1 2.9 2 2 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 OAJ20386.1 - 0.0014 18.8 0.0 0.33 11.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase MobB PF03205.9 OAJ20386.1 - 0.0017 18.0 0.7 0.31 10.7 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_2 PF12797.2 OAJ20386.1 - 0.002 17.9 2.7 0.002 17.9 1.9 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain SRP54 PF00448.17 OAJ20386.1 - 0.002 17.6 1.3 0.23 10.8 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain UPF0079 PF02367.12 OAJ20386.1 - 0.0032 17.1 0.2 0.052 13.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_21 PF14697.1 OAJ20386.1 - 0.0034 17.2 13.0 0.0082 15.9 9.0 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 OAJ20386.1 - 0.0051 16.5 1.9 0.0051 16.5 1.3 2.3 1 1 1 2 2 2 1 4Fe-4S dicluster domain AAA_28 PF13521.1 OAJ20386.1 - 0.0059 16.5 0.3 1.4 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 OAJ20386.1 - 0.0064 15.3 0.0 0.27 10.0 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Fer4_16 PF13484.1 OAJ20386.1 - 0.009 16.7 0.2 0.009 16.7 0.1 2.5 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain AAA_14 PF13173.1 OAJ20386.1 - 0.0094 15.8 0.3 6.5 6.6 0.0 3.1 2 1 1 3 3 2 0 AAA domain Fer4_9 PF13187.1 OAJ20386.1 - 0.01 16.1 2.3 0.01 16.1 1.6 2.3 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 OAJ20386.1 - 0.023 14.7 1.4 0.023 14.7 1.0 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_24 PF13479.1 OAJ20386.1 - 0.041 13.4 0.2 1.7 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 OAJ20386.1 - 0.048 13.0 0.1 6.8 6.0 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Fer4_17 PF13534.1 OAJ20386.1 - 0.053 13.8 0.2 0.053 13.8 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_10 PF12846.2 OAJ20386.1 - 0.077 12.4 0.8 4.8 6.5 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain Rad17 PF03215.10 OAJ20386.1 - 0.089 11.4 0.0 1.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 OAJ20386.1 - 0.18 11.5 0.9 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Fer4_4 PF12800.2 OAJ20386.1 - 0.43 11.0 13.2 0.071 13.4 1.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.2 OAJ20386.1 - 5.7 7.7 13.5 0.11 13.0 2.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain LSM PF01423.17 OAJ20387.1 - 1.8e-09 36.9 0.0 3.4e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 LSM domain Hep_59 PF07052.6 OAJ20388.1 - 2.1e-26 92.3 0.6 2.1e-26 92.3 0.4 2.9 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 HTH_23 PF13384.1 OAJ20389.1 - 4.9e-05 22.8 0.0 0.00033 20.2 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain CPSase_L_D3 PF02787.14 OAJ20389.1 - 9.6e-05 22.1 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_38 PF13936.1 OAJ20389.1 - 0.045 13.3 0.0 0.14 11.7 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.2 OAJ20389.1 - 0.046 13.9 0.9 2.3 8.5 0.0 3.5 4 0 0 4 4 4 0 Helix-turn-helix domain HTH_7 PF02796.10 OAJ20389.1 - 0.092 12.6 0.0 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Sedlin_N PF04628.8 OAJ20391.1 - 4.2e-37 126.9 0.0 8.4e-37 125.9 0.0 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 OAJ20391.1 - 3e-05 23.7 0.0 4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sporozoite_P67 PF05642.6 OAJ20391.1 - 0.56 8.0 6.1 0.65 7.7 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FA_hydroxylase PF04116.8 OAJ20392.1 - 6e-13 49.1 6.6 6.2e-13 49.1 2.8 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Band_7 PF01145.20 OAJ20393.1 - 0.1 12.5 22.1 21 4.9 0.0 4.0 2 1 0 2 2 2 0 SPFH domain / Band 7 family DUF4230 PF14014.1 OAJ20393.1 - 3.3 7.5 8.2 7.1 6.4 5.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4230) CAF-1_p150 PF11600.3 OAJ20393.1 - 7.3 5.8 7.3 13 5.0 5.1 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cutinase PF01083.17 OAJ20427.1 - 1e-28 100.2 0.0 1.2e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ20427.1 - 0.00035 20.2 0.1 0.00035 20.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 OAJ20427.1 - 0.0024 18.1 0.0 0.003 17.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.6 OAJ20427.1 - 0.0026 17.2 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_8 PF06259.7 OAJ20427.1 - 0.02 14.4 0.1 0.051 13.0 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase Abhydrolase_9 PF10081.4 OAJ20427.1 - 0.04 12.6 0.0 0.062 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Abhydrolase_2 PF02230.11 OAJ20427.1 - 0.061 12.7 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.6 OAJ20427.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) MFS_1 PF07690.11 OAJ20428.1 - 6.3e-40 136.9 50.1 8.1e-35 120.1 32.9 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.23 OAJ20430.1 - 2.1e-50 171.3 0.0 2.9e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ20430.1 - 0.0094 16.8 0.0 0.02 15.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Tim17 PF02466.14 OAJ20431.1 - 5.2e-27 94.4 6.1 6.4e-27 94.1 4.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Sugar_tr PF00083.19 OAJ20433.1 - 1.2e-34 119.6 21.7 2.7e-34 118.5 15.1 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ20433.1 - 2.2e-28 99.0 35.6 2.2e-28 99.0 24.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 OAJ20433.1 - 0.011 15.5 1.6 0.56 10.0 0.1 3.3 2 1 1 3 3 3 0 MFS_1 like family Sugar_tr PF00083.19 OAJ20434.1 - 2.9e-35 121.7 19.7 6.3e-35 120.6 13.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ20434.1 - 1.7e-24 86.1 33.3 1.7e-24 86.1 23.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF218 PF02698.12 OAJ20435.1 - 0.0058 16.1 0.4 0.2 11.1 0.0 2.6 3 0 0 3 3 3 2 DUF218 domain Cutinase PF01083.17 OAJ20436.1 - 3.1e-27 95.4 0.0 3.8e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 OAJ20436.1 - 0.003 17.0 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 OAJ20436.1 - 0.016 14.7 0.1 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ20436.1 - 0.029 14.1 0.1 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.20 OAJ20438.1 - 1.3e-59 201.5 0.0 1.2e-58 198.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.3 OAJ20438.1 - 7e-42 143.2 0.0 1.2e-37 129.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.12 OAJ20438.1 - 2e-38 131.9 0.0 3.8e-38 131.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ20438.1 - 0.0002 20.4 0.0 0.65 8.8 0.0 2.7 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 OAJ20438.1 - 0.079 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tom22 PF04281.8 OAJ20439.1 - 0.02 14.4 0.1 11 5.4 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 NTF2 PF02136.15 OAJ20484.1 - 1.3e-28 99.7 0.0 2.2e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 OAJ20484.1 - 0.00029 20.4 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ20484.1 - 0.0068 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_1 PF00036.27 OAJ20485.1 - 6.6e-42 137.6 13.4 2e-10 39.1 0.7 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 OAJ20485.1 - 1.2e-37 127.7 3.4 1.3e-20 73.2 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 OAJ20485.1 - 3.6e-33 112.9 10.6 3.7e-16 58.4 0.4 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 OAJ20485.1 - 1.7e-31 105.2 7.4 1.8e-09 36.6 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 OAJ20485.1 - 1.2e-28 97.1 7.5 3.3e-07 29.3 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 OAJ20485.1 - 4.5e-15 55.3 0.1 1.9e-08 34.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 OAJ20485.1 - 2.9e-10 39.7 0.6 2.8e-05 23.7 0.2 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 OAJ20485.1 - 4.5e-09 36.3 0.0 0.00032 20.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 OAJ20485.1 - 7.2e-08 31.9 1.1 0.017 14.7 0.0 3.7 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 OAJ20485.1 - 1e-05 25.4 0.7 4.3e-05 23.4 0.2 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 OAJ20485.1 - 0.00056 19.3 1.2 0.00065 19.1 0.9 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.8 OAJ20485.1 - 0.00098 18.7 0.1 0.079 12.5 0.1 2.6 1 1 0 1 1 1 1 Caleosin related protein EF-hand_like PF09279.6 OAJ20485.1 - 0.0016 18.4 0.6 0.0078 16.2 0.1 2.2 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like TerB PF05099.8 OAJ20485.1 - 0.005 16.5 0.2 0.63 9.7 0.0 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB Poly_export PF02563.11 OAJ20485.1 - 0.019 14.7 0.1 2.8 7.7 0.0 3.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis/export protein MotA_activ PF09114.5 OAJ20485.1 - 0.024 14.3 0.3 4.3 7.1 0.1 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain RNA_pol_Rpb4 PF03874.11 OAJ20485.1 - 0.054 13.5 1.1 5.8 6.9 0.0 2.5 3 0 0 3 3 3 0 RNA polymerase Rpb4 Tenui_NCP PF04876.7 OAJ20485.1 - 0.066 12.7 0.1 0.98 8.9 0.0 2.0 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein LNS2 PF08235.8 OAJ20485.1 - 0.069 12.7 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Toprim_2 PF13155.1 OAJ20485.1 - 0.075 13.3 0.6 18 5.7 0.3 2.6 1 1 2 3 3 3 0 Toprim-like DUF853 PF05872.7 OAJ20485.1 - 0.081 11.2 0.0 3.3 5.9 0.0 2.1 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) SapB_1 PF05184.10 OAJ20485.1 - 0.091 12.6 0.1 34 4.4 0.0 3.1 3 0 0 3 3 3 0 Saposin-like type B, region 1 KIP1 PF07765.7 OAJ20485.1 - 0.21 11.4 1.2 4.4 7.2 0.0 3.1 3 1 1 4 4 4 0 KIP1-like protein VCBS PF13517.1 OAJ20485.1 - 2.8 8.3 6.4 17 5.8 0.3 2.5 2 2 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DDE_1 PF03184.14 OAJ20486.1 - 1.1e-36 126.0 0.0 1.7e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAJ20486.1 - 1.4e-09 37.5 0.0 5.8e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 OAJ20486.1 - 1.7e-07 31.1 0.1 4e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease NicO PF03824.11 OAJ20486.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein PC_rep PF01851.17 OAJ20488.1 - 7.2e-16 57.4 18.0 0.0015 18.6 0.0 8.9 9 0 0 9 9 9 5 Proteasome/cyclosome repeat Herpes_DNAp_acc PF04929.7 OAJ20488.1 - 2.7 6.8 9.2 4.8 6.0 6.4 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Sel1 PF08238.7 OAJ20489.1 - 5.8e-32 109.4 35.4 6.6e-08 32.9 0.4 9.6 10 0 0 10 10 10 7 Sel1 repeat HLH PF00010.21 OAJ20489.1 - 1.8e-14 53.1 5.2 2.5e-09 36.6 0.2 2.9 2 1 1 3 3 3 2 Helix-loop-helix DNA-binding domain TSC22 PF01166.13 OAJ20490.1 - 0.0019 18.1 2.6 0.0024 17.8 0.1 2.2 2 0 0 2 2 2 1 TSC-22/dip/bun family DUF972 PF06156.8 OAJ20490.1 - 0.022 15.1 3.4 0.23 11.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) GAS PF13851.1 OAJ20490.1 - 0.079 12.1 5.3 1.3 8.1 1.6 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ERM PF00769.14 OAJ20490.1 - 1.1 8.7 10.1 0.11 11.9 2.0 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Rab5-bind PF09311.6 OAJ20490.1 - 9.8 6.0 13.6 43 3.9 9.4 2.0 1 1 0 1 1 1 0 Rabaptin-like protein Ribosomal_60s PF00428.14 OAJ20491.1 - 1.2e-20 73.6 9.8 1.2e-20 73.6 6.8 1.9 3 0 0 3 3 3 1 60s Acidic ribosomal protein DUF4341 PF14241.1 OAJ20491.1 - 1.9e-10 40.2 0.9 1.9e-10 40.2 0.6 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4341) Sulf_transp PF04143.9 OAJ20491.1 - 1.5e-08 34.5 6.1 1.5e-08 34.5 4.3 3.8 4 0 0 4 4 4 2 Sulphur transport CD20 PF04103.10 OAJ20491.1 - 0.0074 16.2 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 CD20-like family Cyclase PF04199.8 OAJ20532.1 - 2.8e-13 49.9 0.0 5.3e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Putative cyclase SAE2 PF08573.5 OAJ20533.1 - 9.6e-12 45.4 2.2 9.6e-12 45.4 1.5 3.6 2 2 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus SBP_bac_7 PF03480.8 OAJ20533.1 - 0.015 14.3 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 DUF3366 PF11846.3 OAJ20533.1 - 0.066 13.0 0.8 0.13 12.1 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) AF1Q PF15017.1 OAJ20533.1 - 3 7.7 6.2 0.66 9.9 1.2 2.2 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator CPSase_L_D2 PF02786.12 OAJ20534.1 - 6e-83 277.2 0.1 1e-82 276.5 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 OAJ20534.1 - 2.8e-68 229.2 0.0 7.1e-68 227.9 0.0 1.7 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 OAJ20534.1 - 3.7e-36 123.5 0.3 1.9e-35 121.2 0.0 2.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 OAJ20534.1 - 5.4e-31 106.7 0.0 1.1e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 OAJ20534.1 - 3.8e-29 102.0 0.0 7.6e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 OAJ20534.1 - 2e-18 66.8 0.2 3.5e-18 65.9 0.2 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAJ20534.1 - 9.6e-18 64.0 0.1 3.6e-17 62.1 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 OAJ20534.1 - 1.3e-14 53.5 0.8 2.5e-14 52.6 0.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 OAJ20534.1 - 2.1e-12 46.5 0.8 5e-05 22.8 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 OAJ20534.1 - 7.4e-11 41.8 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 OAJ20534.1 - 5.2e-07 29.1 0.0 1.1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 OAJ20534.1 - 6.5e-07 28.9 0.3 0.0052 16.1 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein RimK PF08443.6 OAJ20534.1 - 4.9e-06 26.1 0.0 1.3e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 OAJ20534.1 - 1.9e-05 24.5 0.0 4.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 OAJ20534.1 - 0.0023 18.2 0.2 1.9 8.8 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein GARS_A PF01071.14 OAJ20534.1 - 0.0063 16.0 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Acyl-CoA_dh_1 PF00441.19 OAJ20535.1 - 1.4e-27 96.6 2.6 2.2e-27 96.0 1.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 OAJ20535.1 - 1.8e-14 54.1 3.7 1.8e-14 54.1 2.6 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ20535.1 - 3.2e-13 48.9 0.0 6.8e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 OAJ20535.1 - 4.7e-10 40.0 0.0 9.7e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain BTAD PF03704.12 OAJ20536.1 - 0.032 14.5 1.2 0.18 12.1 0.2 2.1 2 0 0 2 2 2 0 Bacterial transcriptional activator domain RVT_1 PF00078.22 OAJ20537.1 - 4.4e-17 62.1 0.1 9.8e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ20537.1 - 1.4e-12 47.7 0.0 2.6e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ20537.1 - 0.032 14.7 0.1 0.11 12.9 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease Nramp PF01566.13 OAJ20537.1 - 0.69 8.6 0.1 1.1 8.0 0.1 1.2 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein zinc_ribbon_2 PF13240.1 OAJ20538.1 - 0.093 12.2 0.1 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Patatin PF01734.17 OAJ20539.1 - 0.027 14.3 0.4 0.039 13.8 0.2 1.3 1 0 0 1 1 1 0 Patatin-like phospholipase Nop14 PF04147.7 OAJ20539.1 - 0.81 7.5 4.3 1 7.1 3.0 1.2 1 0 0 1 1 1 0 Nop14-like family TT_ORF2 PF02957.10 OAJ20539.1 - 1.7 9.3 11.1 3 8.5 0.5 2.3 2 0 0 2 2 2 0 TT viral ORF2 Cwf_Cwc_15 PF04889.7 OAJ20539.1 - 8.1 6.0 10.4 5.6 6.5 5.0 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Transposase_21 PF02992.9 OAJ20541.1 - 5.1e-12 45.3 0.0 1.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 PBP1_TM PF14812.1 OAJ20541.1 - 8.4 6.7 7.6 48 4.3 2.6 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Histone PF00125.19 OAJ20542.1 - 2.3e-23 82.0 0.4 3.6e-23 81.4 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ20542.1 - 0.00034 20.7 0.0 0.00049 20.2 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 OAJ20542.1 - 0.0012 18.2 0.0 0.0014 17.9 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 OAJ20542.1 - 0.084 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAJ20543.1 - 3.4e-23 81.5 0.4 4.6e-23 81.1 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ20543.1 - 0.0004 20.5 0.0 0.00061 19.9 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 OAJ20543.1 - 0.0014 17.9 0.0 0.0017 17.6 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 OAJ20543.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Zn_clus PF00172.13 OAJ20581.1 - 1.9e-06 27.6 9.1 3.4e-06 26.8 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAJ20581.1 - 0.00085 18.2 0.2 0.00085 18.2 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Transposase_21 PF02992.9 OAJ20583.1 - 1e-15 57.4 0.0 2.1e-15 56.4 0.0 1.4 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ20583.1 - 0.00058 19.3 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) ETF_QO PF05187.8 OAJ20584.1 - 6e-40 135.6 0.1 1.3e-39 134.5 0.0 1.6 2 0 0 2 2 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 OAJ20584.1 - 2.1e-08 33.5 1.5 0.00089 18.2 0.2 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ20584.1 - 6.9e-08 31.7 0.2 3.9e-05 22.6 0.2 2.2 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 OAJ20584.1 - 7.4e-07 29.1 0.0 2.2e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAJ20584.1 - 6.3e-05 22.9 0.0 0.00015 21.7 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ20584.1 - 6.4e-05 21.5 0.2 0.0001 20.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 OAJ20584.1 - 9.9e-05 21.5 0.1 0.00066 18.8 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 OAJ20584.1 - 0.00021 20.3 0.0 0.00033 19.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Fer4_7 PF12838.2 OAJ20584.1 - 0.0011 19.3 1.2 0.0027 18.0 0.8 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_oxidored PF12831.2 OAJ20584.1 - 0.0018 17.4 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAJ20584.1 - 0.0022 17.7 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Fer4_10 PF13237.1 OAJ20584.1 - 0.0022 17.7 0.8 0.0041 16.8 0.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox_3 PF13738.1 OAJ20584.1 - 0.0031 17.5 0.0 0.0059 16.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_21 PF14697.1 OAJ20584.1 - 0.0078 16.0 0.3 0.016 15.0 0.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox PF00070.22 OAJ20584.1 - 0.0083 16.5 0.2 0.3 11.5 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ20584.1 - 0.02 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_2 PF12797.2 OAJ20584.1 - 0.053 13.4 0.4 0.14 12.0 0.3 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain FAD_binding_3 PF01494.14 OAJ20584.1 - 0.13 11.2 0.1 0.24 10.3 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Fer4_6 PF12837.2 OAJ20584.1 - 1.5 8.8 4.8 0.45 10.4 0.6 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain CDC50 PF03381.10 OAJ20586.1 - 5.7e-88 294.6 0.0 6.9e-88 294.4 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Pertus-S4-tox PF09275.5 OAJ20586.1 - 0.14 12.2 0.1 0.57 10.2 0.0 2.0 2 0 0 2 2 2 0 Pertussis toxin S4 subunit DUF382 PF04037.8 OAJ20589.1 - 2.2e-55 185.9 0.1 3.8e-55 185.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 OAJ20589.1 - 2.3e-20 71.6 6.1 4.8e-20 70.6 4.3 1.6 1 0 0 1 1 1 1 PSP PBP1_TM PF14812.1 OAJ20589.1 - 2.4 8.5 30.6 0.45 10.8 2.1 3.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Elongin_A PF06881.6 OAJ20590.1 - 2.9e-26 91.9 0.3 4.9e-26 91.2 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Thioredoxin_4 PF13462.1 OAJ20591.1 - 5.5e-07 29.7 0.0 2.9e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin B3_4 PF03483.12 OAJ20592.1 - 1.2e-27 96.4 0.0 2.7e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 OAJ20592.1 - 8.4e-19 67.1 0.0 1e-16 60.5 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain Slu7 PF11708.3 OAJ20593.1 - 2.1e-80 269.9 17.5 2.1e-80 269.9 12.1 3.2 2 2 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor Beta_elim_lyase PF01212.16 OAJ20594.1 - 1.1e-60 205.2 0.0 1.4e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 OAJ20594.1 - 8.9e-06 24.8 0.0 0.00058 18.9 0.0 2.2 3 0 0 3 3 3 2 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 OAJ20594.1 - 0.00012 21.2 0.0 0.00027 20.1 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family bZIP_1 PF00170.16 OAJ20595.1 - 1.5e-08 34.5 6.5 3.4e-06 26.8 2.5 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 OAJ20595.1 - 2.2e-06 27.4 4.9 2.2e-06 27.4 3.4 1.5 2 0 0 2 2 2 1 Basic region leucine zipper DUF3450 PF11932.3 OAJ20595.1 - 0.0072 15.6 1.7 0.011 15.0 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Glutaredoxin2_C PF04399.8 OAJ20595.1 - 0.075 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Ribosomal_S20p PF01649.13 OAJ20595.1 - 0.12 12.7 1.8 0.18 12.1 0.7 1.7 2 0 0 2 2 2 0 Ribosomal protein S20 Spc7 PF08317.6 OAJ20595.1 - 0.21 10.1 3.4 0.34 9.5 2.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 OAJ20595.1 - 3.5 6.4 6.0 5.1 5.9 4.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ribosomal_L28e PF01778.12 OAJ20631.1 - 7.7e-27 94.0 0.4 3.1e-26 92.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 OAJ20631.1 - 1.4e-19 70.0 22.0 1.4e-19 70.0 15.3 3.4 2 1 1 3 3 3 2 Mak16 protein C-terminal region PYC_OADA PF02436.13 OAJ20631.1 - 0.06 12.7 0.6 0.13 11.6 0.4 1.6 1 0 0 1 1 1 0 Conserved carboxylase domain GST_N_3 PF13417.1 OAJ20632.1 - 1.4e-13 50.8 0.0 2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAJ20632.1 - 2.2e-11 43.7 0.0 3.1e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ20632.1 - 1.3e-10 41.1 0.0 1.7e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain RRM_1 PF00076.17 OAJ20633.1 - 5.1e-26 90.1 0.1 3e-12 45.9 0.0 5.2 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ20633.1 - 9.7e-17 60.7 0.0 1.4e-06 28.1 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ20633.1 - 2e-14 53.1 0.0 0.00023 20.9 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RhoGAP PF00620.22 OAJ20634.1 - 8e-38 129.4 0.1 1.8e-37 128.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 OAJ20634.1 - 2.3e-24 85.2 32.6 3.4e-10 39.8 4.7 5.1 5 0 0 5 5 5 4 LIM domain Gar1 PF04410.9 OAJ20635.1 - 4.9e-38 130.0 0.0 4.9e-38 130.0 0.0 2.5 1 1 3 4 4 4 1 Gar1/Naf1 RNA binding region P5CR_dimer PF14748.1 OAJ20636.1 - 8.5e-38 128.6 4.8 1e-37 128.4 2.2 2.0 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 OAJ20636.1 - 1.9e-13 50.6 0.0 4.4e-09 36.6 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent DUF633 PF04816.7 OAJ20636.1 - 0.14 11.5 0.0 2.6 7.3 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF633) Collagen PF01391.13 OAJ20637.1 - 4.8e-08 32.4 19.0 7.7e-08 31.7 13.2 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) AA_permease PF00324.16 OAJ20638.1 - 8.5e-65 218.9 32.9 1.1e-64 218.5 22.8 1.1 1 0 0 1 1 1 1 Amino acid permease Glypican PF01153.14 OAJ20638.1 - 6.1 5.3 5.7 20 3.6 3.9 1.8 1 0 0 1 1 1 0 Glypican WD40 PF00400.27 OAJ20639.1 - 2.5e-30 103.2 10.4 1e-10 41.0 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat dsrm PF00035.20 OAJ20640.1 - 0.099 13.2 0.0 0.099 13.2 0.0 2.9 4 1 1 5 5 5 0 Double-stranded RNA binding motif BRF1 PF07741.8 OAJ20640.1 - 5.6 7.2 18.4 0.12 12.6 4.5 2.7 2 1 0 3 3 3 0 Brf1-like TBP-binding domain Ssl1 PF04056.9 OAJ20641.1 - 2.8e-69 232.5 0.0 5.8e-69 231.5 0.0 1.5 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 OAJ20641.1 - 1.5e-14 53.6 7.5 1.5e-14 53.6 5.2 3.2 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 OAJ20641.1 - 1e-11 45.2 0.0 2.5e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Tfb4 PF03850.9 OAJ20641.1 - 0.33 10.1 5.8 3.9 6.6 4.1 2.3 2 1 1 3 3 3 0 Transcription factor Tfb4 DZR PF12773.2 OAJ20641.1 - 1.9 8.4 23.3 0.13 12.0 3.3 3.4 2 1 0 2 2 2 0 Double zinc ribbon DUF1610 PF07754.6 OAJ20641.1 - 4.8 7.3 16.7 0.44 10.7 0.7 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1610) IBR PF01485.16 OAJ20641.1 - 4.8 7.1 16.7 0.13 12.1 4.4 2.7 2 1 0 2 2 2 0 IBR domain Dynein_light PF01221.13 OAJ20642.1 - 2.9e-37 126.5 0.4 3.5e-37 126.2 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Pkinase PF00069.20 OAJ20643.1 - 9.3e-71 238.0 0.0 1.2e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ20643.1 - 2e-45 154.8 0.0 3e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 OAJ20643.1 - 2.9e-21 75.6 0.1 6.4e-21 74.5 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 OAJ20643.1 - 9.6e-05 21.4 0.0 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ20643.1 - 0.018 14.7 0.2 0.65 9.6 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family DSHCT PF08148.7 OAJ20643.1 - 0.021 14.0 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.9 OAJ20643.1 - 0.22 10.5 0.1 1.8 7.5 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ORC5_C PF14630.1 OAJ20675.1 - 9.5e-41 140.0 0.4 2.8e-38 131.9 0.3 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 OAJ20675.1 - 0.042 13.8 4.7 0.078 12.9 0.9 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 OAJ20675.1 - 0.12 12.5 0.0 0.33 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain zf-HIT PF04438.11 OAJ20676.1 - 1.5e-08 34.0 9.2 2.5e-08 33.4 6.4 1.3 1 0 0 1 1 1 1 HIT zinc finger PAP2_3 PF14378.1 OAJ20676.1 - 0.024 14.1 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 PAP2 superfamily DUF2012 PF09430.5 OAJ20679.1 - 3e-21 75.5 0.0 6.8e-21 74.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2012) Cnd1 PF12717.2 OAJ20680.1 - 4.7e-63 212.2 5.5 4.3e-56 189.5 0.1 4.3 3 2 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 OAJ20680.1 - 1.7e-38 131.9 7.4 1.1e-37 129.2 0.0 4.6 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 OAJ20680.1 - 1.6e-09 37.8 1.5 0.017 15.3 0.0 5.6 6 0 0 6 6 6 2 HEAT repeats Adaptin_N PF01602.15 OAJ20680.1 - 2e-08 33.0 1.7 0.012 13.9 0.0 4.6 3 2 1 4 4 4 4 Adaptin N terminal region HEAT PF02985.17 OAJ20680.1 - 4.5e-06 26.3 1.9 1.1 9.5 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 OAJ20680.1 - 0.00031 21.1 4.0 1.2 9.7 0.0 5.3 5 0 0 5 5 5 2 HEAT-like repeat Cnd3 PF12719.2 OAJ20680.1 - 0.00073 18.6 0.8 0.017 14.1 0.1 3.1 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain DUF2435 PF10363.4 OAJ20680.1 - 0.025 14.4 2.8 13 5.7 0.0 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF2435) PqqD PF05402.7 OAJ20680.1 - 0.036 14.0 0.9 1.8 8.6 0.0 3.7 3 1 1 4 4 4 0 Coenzyme PQQ synthesis protein D (PqqD) Fungal_trans PF04082.13 OAJ20681.1 - 1.7e-05 23.8 0.0 4.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ20681.1 - 0.0022 17.8 5.9 0.22 11.4 0.5 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DSPc PF00782.15 OAJ20682.1 - 6.9e-06 25.6 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAJ20682.1 - 3e-05 23.4 0.0 0.0069 15.7 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase CDKN3 PF05706.7 OAJ20682.1 - 0.039 13.3 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF3802 PF12290.3 OAJ20682.1 - 0.19 12.0 0.2 0.37 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) COX17 PF05051.8 OAJ20683.1 - 0.0056 16.6 3.5 0.14 12.2 0.5 2.5 2 1 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 OAJ20683.1 - 0.0077 15.9 6.1 3.3 7.5 0.9 3.5 1 1 2 3 3 3 2 Cytochrome c oxidase biogenesis protein Cmc1 like YbfN PF13982.1 OAJ20683.1 - 0.017 15.2 0.6 6 7.1 0.0 2.4 2 1 0 2 2 2 0 YbfN-like lipoprotein CHCH PF06747.8 OAJ20683.1 - 0.34 10.8 6.8 5.7 6.9 0.4 3.3 2 2 1 3 3 3 0 CHCH domain UCR_hinge PF02320.11 OAJ20683.1 - 0.38 10.7 4.7 14 5.7 0.1 3.5 2 2 2 4 4 4 0 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 OAJ20683.1 - 0.77 9.8 4.1 4.2 7.4 0.7 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Zn_clus PF00172.13 OAJ20684.1 - 1.7e-06 27.8 4.8 1e-05 25.3 3.4 2.0 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myosin_tail_1 PF01576.14 OAJ20684.1 - 0.075 10.7 0.4 0.11 10.2 0.3 1.1 1 0 0 1 1 1 0 Myosin tail Tyr-DNA_phospho PF06087.7 OAJ20685.1 - 3.4e-38 131.4 0.0 1.5e-21 76.5 0.0 3.3 3 1 0 3 3 3 3 Tyrosyl-DNA phosphodiesterase DCP2 PF05026.8 OAJ20686.1 - 9e-29 99.2 0.1 1.6e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 OAJ20686.1 - 1.7e-13 50.3 0.0 2.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SH3_1 PF00018.23 OAJ20737.1 - 5.4e-25 86.5 0.0 9.2e-12 44.1 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 OAJ20737.1 - 1e-15 57.0 0.0 8.6e-08 31.6 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 OAJ20737.1 - 3.5e-14 52.0 0.0 6.9e-09 35.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 OAJ20737.1 - 1.2e-10 41.1 0.0 2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 OAJ20737.1 - 1.8e-05 24.2 0.0 3.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Rxt3 PF08642.5 OAJ20738.1 - 3.7e-15 56.1 0.0 4.8e-11 42.9 0.0 5.9 4 2 2 6 6 6 2 Histone deacetylation protein Rxt3 zf-BED PF02892.10 OAJ20740.1 - 0.026 14.2 0.2 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 BED zinc finger Sugarporin_N PF11471.3 OAJ20741.1 - 0.0067 16.0 0.5 0.017 14.7 0.4 1.7 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension Peptidase_C48 PF02902.14 OAJ20742.1 - 2.3e-09 37.2 0.1 6e-09 35.8 0.0 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.4 OAJ20742.1 - 3.6e-08 33.4 0.2 5.9e-07 29.5 0.1 2.4 1 1 0 1 1 1 1 MULE transposase domain Spt5_N PF11942.3 OAJ20742.1 - 0.86 10.2 13.0 2 9.0 1.7 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Ank PF00023.25 OAJ20743.1 - 0.088 12.6 0.0 0.31 10.9 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat E3_binding PF02817.12 OAJ20744.1 - 1.3e-09 37.5 0.0 3e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Response_reg PF00072.19 OAJ20745.1 - 2.8e-08 33.7 0.0 3.1e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain CBFD_NFYB_HMF PF00808.18 OAJ20746.1 - 4.9e-13 48.9 0.4 9e-13 48.0 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAJ20746.1 - 0.00024 21.1 0.5 0.0004 20.4 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Prothymosin PF03247.9 OAJ20746.1 - 0.053 13.6 10.1 0.14 12.3 7.0 1.7 1 0 0 1 1 1 0 Prothymosin/parathymosin family Ku PF02735.11 OAJ20747.1 - 8.3e-26 90.6 0.0 4.7e-22 78.3 0.0 2.3 2 0 0 2 2 2 2 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 OAJ20747.1 - 2.1e-14 53.4 0.1 7.4e-14 51.7 0.0 1.8 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 OAJ20747.1 - 5.5e-08 32.1 0.2 1.4e-07 30.8 0.2 1.7 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 OAJ20747.1 - 0.00025 21.5 0.2 0.12 12.9 0.0 2.9 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm Nop53 PF07767.6 OAJ20747.1 - 0.0014 17.7 1.6 0.0023 16.9 1.1 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) BNIP2 PF12496.3 OAJ20747.1 - 0.044 13.9 1.6 0.097 12.8 1.1 1.6 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 PDE6_gamma PF04868.7 OAJ20747.1 - 0.1 12.4 0.2 0.7 9.7 0.0 2.4 2 0 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit Med4 PF10018.4 OAJ20749.1 - 7.5e-19 67.8 4.7 1.1e-18 67.3 3.3 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 zf-C2HC5 PF06221.8 OAJ20750.1 - 4.7e-06 26.2 3.9 9e-06 25.3 2.7 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type TT_ORF2 PF02957.10 OAJ20750.1 - 0.44 11.2 14.0 1.7 9.3 1.9 3.6 3 0 0 3 3 3 0 TT viral ORF2 Mito_carr PF00153.22 OAJ20751.1 - 1.5e-64 213.6 0.1 4.7e-20 71.0 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein HAD_2 PF13419.1 OAJ20789.1 - 3.5e-14 53.4 0.0 2.8e-06 27.6 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAJ20789.1 - 1.1e-06 28.2 0.0 2.7e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 OAJ20789.1 - 7.5e-06 26.5 0.0 4e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 OAJ20789.1 - 0.082 12.2 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Mid2 PF04478.7 OAJ20790.1 - 0.079 12.3 0.2 0.14 11.6 0.2 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.1 OAJ20790.1 - 0.15 12.4 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RNA_pol_Rpb1_5 PF04998.12 OAJ20792.1 - 2.4e-92 309.1 0.1 3.8e-92 308.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 OAJ20792.1 - 6.4e-88 295.2 0.0 1e-87 294.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 OAJ20792.1 - 5.4e-64 215.1 0.0 1.1e-63 214.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 OAJ20792.1 - 6.4e-38 129.9 0.0 1.4e-37 128.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 OAJ20792.1 - 1.2e-27 95.7 0.0 3e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 adh_short PF00106.20 OAJ20793.1 - 1.9e-18 66.9 0.7 4.6e-18 65.6 0.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ20793.1 - 1.1e-08 34.9 0.2 2.2e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ20793.1 - 0.00029 20.7 0.0 0.00041 20.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAJ20793.1 - 0.00057 19.9 0.3 0.0026 17.8 0.1 2.0 1 1 0 2 2 2 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 OAJ20793.1 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 OAJ20793.1 - 0.014 15.8 0.2 0.029 14.7 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 OAJ20793.1 - 0.017 14.7 0.2 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AICARFT_IMPCHas PF01808.13 OAJ20794.1 - 0.0028 16.7 0.0 0.0036 16.4 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme Pex24p PF06398.6 OAJ20795.1 - 3.2e-32 111.7 0.1 2.7e-25 88.9 0.0 2.4 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin Polysacc_deac_1 PF01522.16 OAJ20796.1 - 2.5e-23 82.0 0.0 4.7e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase nec1 PF10379.4 OAJ20796.1 - 0.0027 16.9 0.0 0.0058 15.9 0.0 1.7 1 0 0 1 1 1 1 Virulence protein nec1 Arm PF00514.18 OAJ20797.1 - 0.082 12.7 2.6 5.6 6.9 0.2 3.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Lipase_3 PF01764.20 OAJ20798.1 - 3.6e-13 49.3 0.0 7.8e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Nop14 PF04147.7 OAJ20798.1 - 0.11 10.4 17.5 0.21 9.5 12.1 1.3 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 OAJ20798.1 - 2.5 7.2 11.1 5.9 6.0 7.7 1.5 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.11 OAJ20798.1 - 6.2 5.7 7.8 15 4.4 5.4 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pro_isomerase PF00160.16 OAJ20799.1 - 1.3e-49 168.3 0.0 1.5e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1168 PF06658.7 OAJ20800.1 - 0.33 10.4 7.6 0.72 9.3 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Aminotran_1_2 PF00155.16 OAJ20801.1 - 1.2e-54 185.7 0.0 2e-54 184.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAJ20801.1 - 0.032 13.3 0.0 0.09 11.8 0.0 1.8 2 1 0 2 2 2 0 Beta-eliminating lyase ATP_bind_3 PF01171.15 OAJ20836.1 - 3e-15 56.1 0.0 5.2e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 PP-loop family RecR PF02132.10 OAJ20836.1 - 0.0044 16.4 1.3 0.0044 16.4 0.9 3.0 3 0 0 3 3 3 1 RecR protein tRNA_Me_trans PF03054.11 OAJ20836.1 - 0.078 11.5 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase TF_Zn_Ribbon PF08271.7 OAJ20836.1 - 4 6.8 10.9 1.1 8.6 0.4 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding NuA4 PF09340.5 OAJ20837.1 - 7.2e-20 70.4 0.0 1.5e-19 69.4 0.0 1.5 1 1 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Cyt-b5 PF00173.23 OAJ20838.1 - 3.8e-17 61.8 0.0 5.2e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAD PF02109.11 OAJ20839.1 - 2.8e-47 159.4 2.9 3.8e-47 158.9 2.0 1.2 1 0 0 1 1 1 1 DAD family DUF2061 PF09834.4 OAJ20839.1 - 0.04 14.0 0.1 0.093 12.9 0.1 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2061) MDFI PF15316.1 OAJ20839.1 - 0.046 13.7 0.8 0.063 13.2 0.5 1.2 1 0 0 1 1 1 0 MyoD family inhibitor MAGE_N PF12440.3 OAJ20839.1 - 0.056 13.7 19.5 0.1 12.8 13.5 1.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal DUF1180 PF06679.7 OAJ20839.1 - 0.42 10.4 4.6 0.66 9.8 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Pex14_N PF04695.8 OAJ20839.1 - 0.5 10.3 7.5 1.3 9.0 5.2 1.9 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Alpha_GJ PF03229.8 OAJ20839.1 - 8 6.8 13.8 8.9 6.6 7.0 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J Bac_surface_Ag PF01103.18 OAJ20840.1 - 1.8e-25 90.0 0.3 3.2e-25 89.2 0.2 1.3 1 1 0 1 1 1 1 Surface antigen DUF3381 PF11861.3 OAJ20842.1 - 0.022 14.2 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Paf1 PF03985.8 OAJ20845.1 - 6.3e-33 114.1 32.6 4.3e-18 65.2 0.0 4.3 3 1 1 4 4 4 3 Paf1 Pex24p PF06398.6 OAJ20846.1 - 0.00026 19.9 4.2 0.00047 19.0 2.9 1.4 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Adeno_PV PF03910.8 OAJ20846.1 - 0.05 12.6 8.5 0.088 11.8 5.9 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV UBN2 PF14223.1 OAJ20847.1 - 8.9e-09 35.1 0.1 2.2e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 OAJ20847.1 - 2.1e-07 30.9 0.1 6e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2_2 PF14227.1 OAJ20847.1 - 9.9e-05 21.8 0.0 0.00019 20.9 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.21 OAJ20848.1 - 5.3e-26 91.0 0.0 9.7e-26 90.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ20848.1 - 8e-07 28.6 0.0 6.3e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ20848.1 - 0.0053 16.2 0.1 0.021 14.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Fer2_BFD PF04324.10 OAJ20848.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain TcpQ PF10671.4 OAJ20848.1 - 0.76 9.6 5.4 3.4 7.6 1.0 2.4 1 1 1 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q PRCC PF10253.4 OAJ20849.1 - 1.5e-06 29.0 20.3 9e-06 26.5 14.1 2.4 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Het-C PF07217.6 OAJ20850.1 - 6.4e-217 721.5 0.0 1.2e-216 720.6 0.0 1.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF2780 PF11075.3 OAJ20850.1 - 0.0053 16.8 1.9 0.027 14.5 0.6 2.3 2 0 0 2 2 2 1 Protein of unknown function VcgC/VcgE (DUF2780) SSPI PF14098.1 OAJ20850.1 - 0.12 12.2 0.0 3.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Small, acid-soluble spore protein I IDO PF01231.13 OAJ20850.1 - 0.16 10.3 0.0 7.9 4.7 0.0 2.4 2 0 0 2 2 2 0 Indoleamine 2,3-dioxygenase NAD_binding_1 PF00175.16 OAJ20852.1 - 6.4e-24 84.6 0.0 1.2e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 OAJ20852.1 - 8.3e-19 67.5 0.0 1.8e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 OAJ20852.1 - 3.3e-07 30.3 0.0 2e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 OAJ20852.1 - 0.0017 18.2 0.0 0.013 15.4 0.0 2.4 3 0 0 3 3 3 1 Siderophore-interacting FAD-binding domain DUF2611 PF11022.3 OAJ20853.1 - 3.3e-13 49.5 1.4 1.3e-12 47.5 1.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2611) DUF533 PF04391.7 OAJ20853.1 - 0.077 12.3 0.2 0.09 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) OB_NTP_bind PF07717.11 OAJ20854.1 - 1.2e-27 95.9 0.0 2.6e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 OAJ20854.1 - 2.8e-27 94.6 0.1 8e-27 93.2 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ20854.1 - 6.8e-12 45.0 0.0 1.6e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ20854.1 - 3.3e-05 23.4 0.2 7.6e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 OAJ20854.1 - 5.8e-05 22.1 0.0 0.00016 20.6 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 OAJ20854.1 - 0.00037 20.6 0.0 0.00095 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 OAJ20854.1 - 0.042 14.1 0.3 0.43 10.8 0.2 2.4 1 1 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.1 OAJ20854.1 - 0.054 13.5 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 OAJ20854.1 - 0.057 13.0 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 OAJ20854.1 - 0.13 12.1 0.1 1.6 8.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain ATP11 PF06644.6 OAJ20854.1 - 0.27 10.7 5.6 0.45 9.9 0.0 2.5 2 0 0 2 2 2 0 ATP11 protein AAA_19 PF13245.1 OAJ20854.1 - 0.47 10.2 6.1 0.049 13.3 0.3 2.3 3 0 0 3 3 3 0 Part of AAA domain YqcI_YcgG PF08892.6 OAJ20855.1 - 0.08 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 YqcI/YcgG family DUF2457 PF10446.4 OAJ20897.1 - 0.00062 18.6 4.7 0.00076 18.3 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CobT PF06213.7 OAJ20897.1 - 0.012 14.8 0.4 0.016 14.3 0.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Phytochelatin_C PF09328.5 OAJ20897.1 - 0.049 13.1 0.0 0.061 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) Neisseria_TspB PF05616.8 OAJ20897.1 - 0.062 11.6 0.7 0.08 11.3 0.5 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein PBP1_TM PF14812.1 OAJ20897.1 - 1.2 9.5 9.7 2.3 8.5 6.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRM_1 PF00076.17 OAJ20899.1 - 1.3e-12 47.1 0.0 2.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ20899.1 - 2.5e-10 40.2 0.0 4.2e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ20899.1 - 4.1e-07 29.7 0.0 6.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 OAJ20899.1 - 8.8e-07 29.2 2.8 8.8e-07 29.2 2.0 2.9 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Smg4_UPF3 PF03467.10 OAJ20899.1 - 0.072 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family SDH_alpha PF03313.10 OAJ20900.1 - 3.3e-93 311.8 1.4 5.6e-93 311.0 1.0 1.3 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 OAJ20900.1 - 1.4e-51 174.6 0.0 2.6e-51 173.7 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain Suf PF05843.9 OAJ20901.1 - 2.9e-79 266.7 0.0 2.3e-76 257.1 0.0 3.9 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 OAJ20901.1 - 9.2e-07 28.9 1.8 19 6.2 0.0 7.4 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ20901.1 - 2.6e-05 24.4 0.0 1.1 9.6 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat Methyltransf_23 PF13489.1 OAJ20902.1 - 2.1e-09 37.3 0.0 7.1e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ20902.1 - 5e-08 33.3 0.0 1.3e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ20902.1 - 5.4e-05 23.4 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ20902.1 - 0.00069 19.6 0.0 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ20902.1 - 0.00096 18.5 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 OAJ20902.1 - 0.0045 17.5 0.0 0.0073 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ20902.1 - 0.0047 16.5 0.0 0.0094 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ20902.1 - 0.027 14.9 0.0 0.075 13.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain FmrO PF07091.6 OAJ20902.1 - 0.052 12.5 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Saccharop_dh PF03435.13 OAJ20902.1 - 0.053 12.4 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Med12 PF09497.5 OAJ20902.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Transcription mediator complex subunit Med12 zf-C2H2_4 PF13894.1 OAJ20903.1 - 2.1e-10 40.1 6.3 0.00012 22.1 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 OAJ20903.1 - 2.1e-09 37.1 9.7 0.00039 20.5 0.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAJ20903.1 - 3e-08 33.5 4.9 2e-06 27.8 0.5 3.0 2 0 0 2 2 2 2 Zinc-finger double domain AKAP95 PF04988.7 OAJ20904.1 - 0.018 14.8 0.3 0.033 13.9 0.2 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Phage_Gp23 PF10669.4 OAJ20904.1 - 0.48 10.5 6.1 0.18 11.8 2.3 1.7 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DivIVA PF05103.8 OAJ20904.1 - 4.2 7.4 10.9 0.3 11.1 3.9 1.7 2 0 0 2 2 2 0 DivIVA protein Peptidase_A22B PF04258.8 OAJ20905.1 - 5.9e-70 236.0 7.2 7.6e-70 235.7 5.0 1.1 1 0 0 1 1 1 1 Signal peptide peptidase CENP-B_dimeris PF09026.5 OAJ20905.1 - 0.00017 21.7 0.6 0.0013 18.9 0.0 2.2 2 0 0 2 2 2 1 Centromere protein B dimerisation domain FAM176 PF14851.1 OAJ20905.1 - 0.3 10.7 0.0 0.3 10.7 0.0 2.1 2 1 0 2 2 2 0 FAM176 family DcpS_C PF11969.3 OAJ20906.1 - 0.00019 21.6 0.6 0.00034 20.8 0.4 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Abhydrolase_4 PF08386.5 OAJ20907.1 - 3.4e-14 52.5 0.0 1.5e-13 50.4 0.0 2.0 1 1 1 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 OAJ20907.1 - 4.2e-12 46.1 0.0 8.8e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ20907.1 - 7.5e-08 32.5 0.0 6.3e-07 29.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ20907.1 - 4.6e-05 23.2 0.0 0.00021 21.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DcpS_C PF11969.3 OAJ20908.1 - 1.3e-10 41.5 0.2 5.1e-10 39.5 0.2 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 OAJ20908.1 - 1.2e-06 28.9 0.5 0.041 14.4 0.0 2.4 2 0 0 2 2 2 2 HIT domain Pkinase PF00069.20 OAJ20909.1 - 1.6e-66 224.1 0.0 2.3e-66 223.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ20909.1 - 1.8e-42 145.2 0.0 2.8e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 OAJ20909.1 - 2.9e-13 49.6 0.0 7.5e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 OAJ20909.1 - 3.4e-12 46.3 0.1 9e-12 45.0 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 OAJ20909.1 - 3.6e-12 45.9 0.0 6.4e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 OAJ20909.1 - 1.6e-07 30.6 0.0 0.00062 18.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 OAJ20909.1 - 0.052 12.6 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RA PF00788.18 OAJ20909.1 - 0.083 13.3 0.0 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Nop14 PF04147.7 OAJ20909.1 - 0.31 8.9 6.2 0.47 8.3 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family Seadorna_VP7 PF07387.6 OAJ20909.1 - 1.3 7.8 0.0 2.7 6.7 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 NOA36 PF06524.7 OAJ20909.1 - 4.1 6.5 4.8 7 5.8 3.3 1.3 1 0 0 1 1 1 0 NOA36 protein Cep57_MT_bd PF06657.8 OAJ20910.1 - 7.1e-10 38.7 2.0 7.1e-10 38.7 1.4 3.1 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 Vpu PF00558.14 OAJ20910.1 - 0.19 11.2 3.9 15 5.2 2.1 2.8 2 0 0 2 2 2 0 Vpu protein F-box-like PF12937.2 OAJ20946.1 - 0.00067 19.3 0.1 0.0025 17.5 0.1 2.0 1 0 0 1 1 1 1 F-box-like HALZ PF02183.13 OAJ20947.1 - 0.048 13.3 0.1 0.085 12.5 0.1 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper MtrD PF04207.7 OAJ20947.1 - 0.5 9.6 6.0 1.1 8.5 4.2 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D DUF3437 PF11919.3 OAJ20948.1 - 1.7e-30 104.5 1.3 3e-29 100.5 0.0 3.5 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.1 OAJ20948.1 - 0.00011 22.4 0.5 0.035 14.4 0.0 4.4 4 2 1 5 5 5 1 HEAT repeats HEAT PF02985.17 OAJ20948.1 - 0.00026 20.7 0.7 0.046 13.8 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat DUF1546 PF07571.8 OAJ20948.1 - 0.009 16.1 0.4 0.94 9.6 0.0 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF1546) Prp31_C PF09785.4 OAJ20949.1 - 1.1e-37 129.2 6.9 1.1e-37 129.2 4.8 2.0 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 OAJ20949.1 - 2.9e-36 124.0 0.4 5.5e-36 123.1 0.3 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 OAJ20949.1 - 1.6e-20 72.6 0.6 3.7e-20 71.4 0.0 2.0 2 0 0 2 2 2 1 NOSIC (NUC001) domain Daxx PF03344.10 OAJ20949.1 - 0.098 11.1 15.6 0.0026 16.3 6.2 1.6 2 0 0 2 2 2 0 Daxx Family NOA36 PF06524.7 OAJ20949.1 - 0.93 8.6 13.6 1.6 7.9 9.4 1.3 1 0 0 1 1 1 0 NOA36 protein Rhomboid PF01694.17 OAJ20952.1 - 8.1e-30 103.7 12.3 8.1e-30 103.7 8.5 2.1 3 0 0 3 3 3 1 Rhomboid family zf-C2H2_2 PF12756.2 OAJ20953.1 - 4.3e-36 123.0 1.6 4.9e-28 97.2 0.0 3.3 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 OAJ20953.1 - 6.5e-08 32.4 12.7 7.8e-06 25.8 0.4 3.4 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAJ20953.1 - 2.9e-07 30.4 5.3 3.4e-07 30.2 0.5 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type AKAP95 PF04988.7 OAJ20953.1 - 0.0033 17.2 0.2 0.006 16.3 0.1 1.4 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) DUF2890 PF11081.3 OAJ20953.1 - 0.004 17.2 5.2 0.004 17.2 3.6 3.1 2 1 0 3 3 3 1 Protein of unknown function (DUF2890) zf-C2H2 PF00096.21 OAJ20953.1 - 0.024 14.9 18.1 0.029 14.6 0.3 4.6 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 OAJ20953.1 - 0.075 12.9 5.2 21 5.2 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger TEX19 PF15553.1 OAJ20953.1 - 0.19 11.6 8.3 2.8 7.7 3.0 2.5 2 0 0 2 2 2 0 Testis-expressed protein 19 zf-C2H2_4 PF13894.1 OAJ20953.1 - 0.28 11.6 11.9 1.9 9.0 0.1 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-DBF PF07535.7 OAJ20953.1 - 0.46 10.2 0.0 0.46 10.2 0.0 2.4 3 0 0 3 3 3 0 DBF zinc finger Abhydrolase_3 PF07859.8 OAJ20954.1 - 1.2e-40 139.3 1.3 1.4e-39 135.8 0.9 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAJ20954.1 - 1.2e-10 40.8 0.2 2.3e-10 39.8 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 OAJ20954.1 - 0.00074 19.2 0.1 0.0013 18.5 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 OAJ20954.1 - 0.29 9.5 0.2 3.4 6.0 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) tRNA-synt_2 PF00152.15 OAJ20955.1 - 8.2e-76 254.9 0.0 1.2e-75 254.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 OAJ20955.1 - 1e-15 57.3 0.1 1.8e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 OAJ20955.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 OAJ20955.1 - 0.0042 16.3 0.2 0.29 10.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Pkinase PF00069.20 OAJ20957.1 - 1.6e-40 138.9 0.0 4.1e-30 104.8 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ20957.1 - 6.1e-23 81.2 0.0 4.6e-16 58.6 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 OAJ20957.1 - 0.02 14.6 4.4 0.12 12.0 0.0 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ20957.1 - 0.11 11.4 0.0 0.77 8.6 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Serglycin PF04360.7 OAJ20957.1 - 0.15 11.8 6.5 0.47 10.1 4.5 1.8 1 0 0 1 1 1 0 Serglycin LSM PF01423.17 OAJ20958.1 - 1.7e-13 49.9 0.0 2.6e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 OAJ20958.1 - 7.4e-05 22.5 0.0 9.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2642 PF10842.3 OAJ20958.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) Xan_ur_permease PF00860.15 OAJ21003.1 - 2e-54 184.5 31.2 5e-53 179.9 21.6 2.1 1 1 0 1 1 1 1 Permease family TFIIA PF03153.8 OAJ21004.1 - 2.6e-47 162.5 7.7 1.7e-27 97.2 3.9 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit DEAD PF00270.24 OAJ21005.1 - 5.7e-12 45.4 0.0 9.3e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ21005.1 - 0.019 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Cyclin_N PF00134.18 OAJ21008.1 - 1.5e-11 43.9 0.4 1.5e-11 43.9 0.3 2.4 3 0 0 3 3 3 1 Cyclin, N-terminal domain TFIIB PF00382.14 OAJ21008.1 - 0.00023 20.9 0.5 0.00055 19.6 0.4 1.7 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Helicase_C_3 PF13625.1 OAJ21009.1 - 1.9e-25 89.1 0.0 4.7e-25 87.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ21009.1 - 3.4e-14 53.1 0.0 6.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 OAJ21009.1 - 2.3e-11 43.0 0.0 3.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ21009.1 - 9e-10 38.2 0.1 2.3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RNA_pol_A_bac PF01000.21 OAJ21010.1 - 9.3e-27 93.4 0.0 2e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 OAJ21010.1 - 7.1e-19 66.6 0.0 9.4e-19 66.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 OAJ21010.1 - 0.00044 19.7 0.1 0.0053 16.2 0.0 2.6 2 1 1 3 3 3 1 Domain of unknown function DUF22 Peptidase_M24 PF00557.19 OAJ21011.1 - 6.6e-49 166.3 0.0 9.4e-49 165.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 OAJ21011.1 - 1e-34 118.8 0.0 1.8e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.19 OAJ21012.1 - 8.2e-41 139.8 0.0 1.2e-40 139.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 OAJ21012.1 - 6.5e-20 71.9 0.0 5.2e-19 69.0 0.0 2.3 2 1 1 3 3 3 1 Creatinase/Prolidase N-terminal domain Ribosomal_S4 PF00163.14 OAJ21013.1 - 3.4e-12 46.5 0.5 4.9e-12 46.0 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 OAJ21013.1 - 1.5e-10 40.3 0.0 2.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 S4 domain Abhydrolase_3 PF07859.8 OAJ21014.1 - 1.1e-32 113.3 0.0 1.4e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ21014.1 - 0.00054 19.7 0.0 0.00091 19.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 OAJ21014.1 - 0.0026 17.0 0.1 2 7.6 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family DUF2424 PF10340.4 OAJ21014.1 - 0.025 13.2 0.0 0.036 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Thioesterase PF00975.15 OAJ21014.1 - 0.12 12.5 0.1 0.24 11.6 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 OAJ21014.1 - 0.19 11.0 0.6 1.8 7.9 0.2 2.5 2 1 0 2 2 2 0 Putative esterase TRP PF06011.7 OAJ21015.1 - 6.7e-76 255.6 3.5 1e-75 255.0 2.4 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 OAJ21015.1 - 1e-28 100.1 0.0 1.5e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 OAJ21015.1 - 0.069 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 ML domain Ribosomal_L27 PF01016.14 OAJ21016.1 - 3.8e-35 119.5 0.2 6.8e-35 118.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Met_asp_mut_E PF06368.6 OAJ21018.1 - 0.17 10.0 0.0 0.24 9.5 0.0 1.1 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Sin_N PF04801.8 OAJ21065.1 - 9.3e-15 54.3 0.3 3.7e-13 49.1 0.0 2.4 2 0 0 2 2 2 2 Sin-like protein conserved region RRM_1 PF00076.17 OAJ21066.1 - 3.4e-16 58.6 0.0 4.7e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ21066.1 - 9.8e-13 47.8 0.0 1.5e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ21066.1 - 9.3e-09 35.0 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ21066.1 - 0.021 14.6 0.3 0.042 13.7 0.2 1.6 1 1 0 1 1 1 0 RNA binding motif DUF3227 PF11537.3 OAJ21066.1 - 0.1 12.7 0.3 0.18 11.9 0.1 1.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3227) MoaE PF02391.12 OAJ21067.1 - 5.8e-27 93.8 0.0 1.9e-26 92.1 0.0 1.8 1 1 0 1 1 1 1 MoaE protein TOM13 PF08219.6 OAJ21068.1 - 2.2e-10 40.1 1.1 2.2e-10 40.1 0.8 2.0 2 1 0 2 2 2 1 Outer membrane protein TOM13 TFIIA PF03153.8 OAJ21068.1 - 0.016 15.1 2.6 0.024 14.5 1.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CENP-B_dimeris PF09026.5 OAJ21068.1 - 0.15 12.2 11.3 0.4 10.9 7.9 1.6 2 0 0 2 2 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 OAJ21068.1 - 0.22 10.7 7.2 0.29 10.3 5.0 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 OAJ21068.1 - 0.22 9.4 8.0 0.25 9.2 5.6 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 OAJ21068.1 - 0.49 9.9 7.9 0.71 9.3 5.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin EBV-NA3 PF05009.7 OAJ21068.1 - 1.3 8.2 3.8 1.8 7.7 2.6 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Nucleo_P87 PF07267.6 OAJ21068.1 - 1.9 7.1 7.0 2.4 6.7 4.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Vac7 PF12751.2 OAJ21068.1 - 7.9 5.2 9.1 11 4.7 6.3 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 BTV_NS2 PF04514.7 OAJ21068.1 - 7.9 5.2 9.0 10 4.8 6.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PBP1_TM PF14812.1 OAJ21068.1 - 8.2 6.8 10.9 19 5.6 7.5 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-Tim10_DDP PF02953.10 OAJ21069.1 - 5.1e-23 80.1 0.8 6.2e-23 79.8 0.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger QCR10 PF09796.4 OAJ21070.1 - 1.6e-21 75.6 0.3 2.2e-21 75.2 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 OAJ21070.1 - 0.026 14.2 2.4 0.048 13.3 1.6 1.6 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Rep_fac_C PF08542.6 OAJ21071.1 - 4.8e-19 68.1 0.0 9.8e-19 67.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 OAJ21071.1 - 3.1e-12 46.8 0.0 6.1e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 OAJ21071.1 - 1.8e-11 43.9 0.0 7.5e-10 38.7 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 OAJ21071.1 - 1e-07 32.1 0.1 2.5e-06 27.6 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.6 OAJ21071.1 - 3.3e-06 26.7 0.0 5.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 OAJ21071.1 - 4.5e-06 25.6 0.0 0.00085 18.1 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 OAJ21071.1 - 7.2e-06 25.9 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ21071.1 - 1.3e-05 25.3 0.1 0.0036 17.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 OAJ21071.1 - 4.2e-05 23.1 0.0 0.02 14.3 0.0 2.7 1 1 2 3 3 3 1 AAA-like domain RuvB_N PF05496.7 OAJ21071.1 - 8.7e-05 21.6 0.0 0.00018 20.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus ArgK PF03308.11 OAJ21071.1 - 0.00065 18.5 0.0 0.0014 17.4 0.0 1.6 1 0 0 1 1 1 1 ArgK protein NTPase_1 PF03266.10 OAJ21071.1 - 0.0025 17.5 0.0 0.039 13.6 0.0 2.3 1 1 1 2 2 2 1 NTPase Viral_helicase1 PF01443.13 OAJ21071.1 - 0.0026 17.3 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 OAJ21071.1 - 0.0026 17.4 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_31 PF13614.1 OAJ21071.1 - 0.0046 16.9 0.0 0.011 15.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain FtsK_SpoIIIE PF01580.13 OAJ21071.1 - 0.0053 16.2 0.0 0.015 14.7 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family Mg_chelatase PF01078.16 OAJ21071.1 - 0.013 14.6 0.0 0.1 11.7 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 OAJ21071.1 - 0.014 14.9 0.1 0.069 12.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 OAJ21071.1 - 0.016 14.4 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MipZ PF09140.6 OAJ21071.1 - 0.026 13.6 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ SRP54 PF00448.17 OAJ21071.1 - 0.031 13.7 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.9 OAJ21071.1 - 0.031 13.9 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 OAJ21071.1 - 0.044 12.7 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.24 OAJ21071.1 - 0.052 13.0 0.1 0.33 10.4 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase MobB PF03205.9 OAJ21071.1 - 0.055 13.1 0.1 0.28 10.8 0.0 2.0 1 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 OAJ21071.1 - 0.07 12.5 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Mito_carr PF00153.22 OAJ21072.1 - 5.2e-38 128.6 5.9 1.1e-15 57.0 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein RAP1 PF07218.6 OAJ21072.1 - 1.3 7.0 4.3 1.7 6.6 3.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ApbA_C PF08546.6 OAJ21073.1 - 6.3e-19 68.2 0.0 2.6e-09 37.1 0.0 3.2 4 1 0 4 4 4 2 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 OAJ21073.1 - 2.3e-16 59.6 0.0 9.8e-12 44.5 0.0 2.5 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Cytomega_UL20A PF05984.7 OAJ21075.1 - 0.0079 16.3 1.4 0.47 10.6 0.1 2.3 2 0 0 2 2 2 2 Cytomegalovirus UL20A protein TRAUB PF08164.7 OAJ21075.1 - 0.44 10.6 3.9 1.5 9.0 2.7 1.9 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal ADH_zinc_N_2 PF13602.1 OAJ21076.1 - 1.2e-17 65.0 0.1 1.6e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 OAJ21076.1 - 1.1e-08 34.6 0.0 1.5e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RNase_PH PF01138.16 OAJ21077.1 - 5.9e-16 58.9 0.0 1.2e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 ADH_zinc_N_2 PF13602.1 OAJ21078.1 - 2.6e-17 63.9 0.0 8.6e-17 62.2 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 OAJ21078.1 - 4.3e-17 61.8 0.2 8.7e-17 60.8 0.2 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ21078.1 - 4.7e-10 39.1 0.0 1.2e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 OAJ21078.1 - 0.012 15.1 0.2 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 OAJ21078.1 - 0.044 13.3 0.1 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CMAS PF02353.15 OAJ21078.1 - 0.048 12.7 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase SSB PF00436.20 OAJ21078.1 - 0.11 12.3 0.2 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 Single-strand binding protein family 2-Hacid_dh_C PF02826.14 OAJ21078.1 - 0.15 11.1 0.0 0.33 10.0 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_S9_N PF02897.10 OAJ21079.1 - 7.8e-78 261.8 0.1 1e-77 261.5 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 OAJ21079.1 - 1.2e-47 161.9 0.0 2e-47 161.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 OAJ21079.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Methyltransf_6 PF03737.10 OAJ21079.1 - 0.081 12.7 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Demethylmenaquinone methyltransferase Imm21 PF15569.1 OAJ21079.1 - 0.12 12.1 1.1 6.4 6.6 0.1 2.6 2 0 0 2 2 2 0 Immunity protein 21 Adap_comp_sub PF00928.16 OAJ21080.1 - 3.3e-40 137.8 0.0 4.4e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family PX PF00787.19 OAJ21081.1 - 1.7e-19 69.6 0.0 3.1e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 PX domain SNF2_N PF00176.18 OAJ21082.1 - 2.7e-54 183.9 0.0 2.7e-54 183.9 0.0 3.0 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ21082.1 - 1.9e-13 50.0 0.0 1e-12 47.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.19 OAJ21082.1 - 3e-09 36.4 0.2 0.00043 19.8 0.0 3.2 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 OAJ21082.1 - 8.9e-06 25.3 6.7 0.016 14.9 0.1 2.8 2 0 0 2 2 2 2 PHD-finger MULE PF10551.4 OAJ21117.1 - 3.7e-12 46.2 0.1 1.4e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 OAJ21117.1 - 2.1e-08 33.1 2.5 1e-07 30.9 0.1 2.2 2 0 0 2 2 2 1 Transposase, Mutator family FAR1 PF03101.10 OAJ21117.1 - 0.014 15.9 1.2 0.029 14.8 0.8 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF3381 PF11861.3 OAJ21119.1 - 0.32 10.4 1.4 0.33 10.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF619 PF04768.8 OAJ21120.1 - 7e-28 97.1 0.0 7.4e-19 67.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF619) Adaptin_N PF01602.15 OAJ21122.1 - 2.1e-141 471.8 5.3 2.5e-141 471.5 3.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 OAJ21122.1 - 4.1e-23 81.8 3.5 8.3e-23 80.9 2.5 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT PF02985.17 OAJ21122.1 - 0.0022 17.8 0.3 16 5.9 0.0 5.2 4 0 0 4 4 4 1 HEAT repeat RIX1 PF08167.7 OAJ21122.1 - 0.0046 16.6 0.3 0.056 13.1 0.0 3.0 2 1 1 3 3 3 1 rRNA processing/ribosome biogenesis TIP120 PF08623.5 OAJ21122.1 - 0.013 15.1 3.2 0.018 14.6 0.2 2.7 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 OAJ21122.1 - 0.35 10.6 6.4 0.15 11.8 0.5 2.9 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 rve PF00665.21 OAJ21123.1 - 2.5e-08 34.0 0.0 5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ21124.1 - 4.1e-24 85.1 0.0 5.8e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Orthopox_F8 PF05886.6 OAJ21125.1 - 0.0057 16.4 6.1 0.14 12.0 1.5 3.3 2 0 0 2 2 2 2 Orthopoxvirus F8 protein Orn_Arg_deC_N PF02784.11 OAJ21126.1 - 1.7e-35 122.3 0.0 2.4e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 OAJ21126.1 - 1.1e-15 57.3 0.0 1.9e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Abhydrolase_6 PF12697.2 OAJ21126.1 - 0.0014 18.5 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Phos_pyr_kin PF08543.7 OAJ21127.1 - 2.3e-70 236.6 0.1 6.7e-53 179.4 0.1 3.2 2 1 1 3 3 3 3 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 OAJ21127.1 - 9.6e-27 94.1 0.1 1.5e-26 93.4 0.1 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.10 OAJ21127.1 - 0.0079 15.3 0.8 1 8.4 0.0 2.6 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family PfkB PF00294.19 OAJ21127.1 - 0.0092 15.1 0.0 0.32 10.0 0.0 2.6 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Enolase_N PF03952.11 OAJ21127.1 - 0.089 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Enolase, N-terminal domain NPBW PF15180.1 OAJ21127.1 - 0.1 12.2 0.4 1.8 8.2 0.1 2.4 2 0 0 2 2 2 0 Neuropeptides B and W Peptidase_M43 PF05572.8 OAJ21128.1 - 8.9e-15 54.6 0.0 1.3e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 OAJ21128.1 - 6.6e-05 23.4 0.1 0.00034 21.1 0.1 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAJ21128.1 - 0.0013 18.6 1.7 0.0034 17.3 1.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.4 OAJ21128.1 - 0.004 16.0 0.0 0.0061 15.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_2 PF13574.1 OAJ21128.1 - 0.005 16.9 1.1 0.0099 15.9 0.6 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 OAJ21128.1 - 0.0073 16.0 0.0 0.0089 15.7 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.1 OAJ21128.1 - 0.01 15.3 0.3 0.022 14.2 0.1 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.8 OAJ21129.1 - 3e-15 56.1 0.0 4.5e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 OAJ21129.1 - 2.6e-06 27.9 0.1 1.1e-05 25.9 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAJ21129.1 - 4e-05 23.6 1.0 5.8e-05 23.1 0.7 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 OAJ21129.1 - 0.00036 20.6 1.8 0.0006 19.9 1.2 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 OAJ21129.1 - 0.0014 18.2 0.9 0.003 17.1 0.2 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 OAJ21129.1 - 0.024 14.3 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M54 PF07998.6 OAJ21129.1 - 0.028 14.2 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 PseudoU_synth_1 PF01416.15 OAJ21173.1 - 2.8e-21 75.9 0.0 2.4e-11 43.9 0.0 2.8 3 0 0 3 3 3 2 tRNA pseudouridine synthase TT_ORF2 PF02957.10 OAJ21173.1 - 2.4 8.8 5.5 5.4 7.7 0.3 2.9 2 0 0 2 2 2 0 TT viral ORF2 zf-CCHC_4 PF14392.1 OAJ21174.1 - 1.2 8.8 9.3 2.2 8.0 1.5 2.5 2 0 0 2 2 2 0 Zinc knuckle CBF PF03914.12 OAJ21176.1 - 1.1e-34 119.2 0.0 4.8e-34 117.1 0.0 2.1 2 0 0 2 2 2 1 CBF/Mak21 family WLM PF08325.5 OAJ21178.1 - 4.7e-40 137.4 0.0 9e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 WLM domain Casc1 PF12366.3 OAJ21179.1 - 2.2 7.7 10.6 0.61 9.5 0.8 2.2 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 Acetyltransf_1 PF00583.19 OAJ21180.1 - 9.9e-09 35.1 0.0 5.1e-08 32.8 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ21180.1 - 4.6e-05 23.4 0.0 9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAJ21180.1 - 0.0052 16.6 0.0 0.021 14.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 OAJ21180.1 - 0.03 14.2 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nop14 PF04147.7 OAJ21180.1 - 0.035 12.0 18.7 0.041 11.8 1.3 3.0 3 0 0 3 3 3 0 Nop14-like family FR47 PF08445.5 OAJ21180.1 - 0.12 12.1 0.0 5.5 6.8 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein Rota_VP2 PF05087.7 OAJ21180.1 - 2.7 5.8 3.2 4 5.2 2.2 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein alpha-hel2 PF14456.1 OAJ21180.1 - 7.9 5.1 9.8 0.31 9.7 2.4 1.8 2 0 0 2 2 2 0 Alpha-helical domain 2 Sas10_Utp3 PF04000.10 OAJ21181.1 - 1.5e-08 34.7 0.5 3.5e-08 33.5 0.3 1.7 1 1 0 1 1 1 1 Sas10/Utp3/C1D family tRNA-synt_2 PF00152.15 OAJ21182.1 - 2.5e-78 263.2 0.2 4.3e-78 262.4 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAJ21182.1 - 1.9e-05 24.4 0.0 3.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 OAJ21182.1 - 0.031 13.4 0.5 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) PcfJ PF14284.1 OAJ21182.1 - 0.57 9.6 5.4 11 5.4 1.4 2.5 2 1 0 2 2 2 0 PcfJ-like protein PAP2 PF01569.16 OAJ21184.1 - 1.7e-12 47.1 3.5 2.7e-12 46.4 2.4 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 OAJ21184.1 - 0.039 13.6 0.1 0.039 13.6 0.1 2.5 3 1 0 3 3 3 0 Divergent PAP2 family DUF2517 PF10725.4 OAJ21184.1 - 0.053 13.2 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) SNF2_N PF00176.18 OAJ21185.1 - 3.6e-65 219.7 0.0 5e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 OAJ21185.1 - 6.2e-19 67.9 0.0 1.2e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 OAJ21185.1 - 6.2e-15 54.8 0.0 1.5e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ21185.1 - 7.1e-05 22.7 0.0 0.00036 20.4 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ21185.1 - 9.4e-05 21.9 0.0 0.00026 20.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.1 OAJ21185.1 - 0.0012 18.5 10.8 0.0022 17.6 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ21185.1 - 0.0015 18.1 13.8 0.0027 17.3 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ21185.1 - 0.0016 18.3 15.2 0.0029 17.5 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ21185.1 - 0.0066 16.2 13.0 0.012 15.3 9.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAJ21185.1 - 0.074 12.7 14.2 0.13 11.9 9.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DEAD_2 PF06733.10 OAJ21185.1 - 0.1 11.9 0.0 0.36 10.1 0.0 1.7 1 1 0 1 1 1 0 DEAD_2 Ribosomal_L22e PF01776.12 OAJ21186.1 - 1.2e-45 154.0 0.0 1.4e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family NIF PF03031.13 OAJ21187.1 - 5e-19 68.5 0.0 1.5e-16 60.4 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 OAJ21187.1 - 2.7e-09 36.7 0.0 5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 OAJ21187.1 - 8e-07 29.1 0.0 1.6e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BUD22 PF09073.5 OAJ21187.1 - 0.0022 17.1 3.1 0.0022 17.1 2.2 3.5 3 1 0 3 3 3 1 BUD22 UQ_con PF00179.21 OAJ21232.1 - 7.2e-47 158.3 0.0 8.4e-47 158.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ21232.1 - 4.2e-05 23.3 0.0 5.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 OAJ21232.1 - 0.016 14.8 0.1 0.033 13.8 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 OAJ21232.1 - 0.14 12.0 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain Pkinase PF00069.20 OAJ21233.1 - 7.4e-67 225.2 0.0 1.8e-66 223.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ21233.1 - 4.2e-50 170.2 0.0 6.8e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ21233.1 - 0.018 14.0 1.1 0.034 13.1 0.0 1.9 2 0 0 2 2 2 0 Kinase-like PAT1 PF09770.4 OAJ21233.1 - 2.2 6.3 18.5 3.5 5.7 12.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2422 PF10337.4 OAJ21233.1 - 8 5.1 8.9 12 4.4 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Asp PF00026.18 OAJ21234.1 - 3.6e-47 161.1 0.0 4.5e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ21234.1 - 9.1e-07 28.9 0.1 2e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal DUF4544 PF15077.1 OAJ21234.1 - 0.32 10.4 1.1 0.5 9.8 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) PHD PF00628.24 OAJ21235.1 - 4.5e-07 29.4 13.8 7.9e-07 28.6 9.5 1.4 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 OAJ21235.1 - 0.0069 16.7 0.0 0.0069 16.7 0.0 4.5 3 2 0 3 3 3 1 SET domain ANF_receptor PF01094.23 OAJ21235.1 - 0.17 10.6 0.1 0.39 9.4 0.0 1.5 2 0 0 2 2 2 0 Receptor family ligand binding region PHD_2 PF13831.1 OAJ21235.1 - 0.35 10.2 5.0 0.61 9.4 3.5 1.3 1 0 0 1 1 1 0 PHD-finger HEAT PF02985.17 OAJ21236.1 - 0.00022 21.0 8.9 1.4 9.1 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 OAJ21236.1 - 0.00029 21.0 6.0 0.033 14.4 0.0 5.0 3 2 2 5 5 5 2 HEAT repeats Het-C PF07217.6 OAJ21236.1 - 0.018 13.2 0.1 0.039 12.1 0.0 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C HEAT_EZ PF13513.1 OAJ21236.1 - 3.3 8.3 10.8 64 4.2 0.0 5.7 5 0 0 5 5 5 0 HEAT-like repeat Actin PF00022.14 OAJ21237.1 - 1.8e-132 441.5 0.0 2e-132 441.3 0.0 1.0 1 0 0 1 1 1 1 Actin Sec63 PF02889.11 OAJ21238.1 - 2.3e-180 598.6 0.0 5.5e-97 324.7 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 OAJ21238.1 - 1.4e-45 154.8 0.0 1.5e-27 96.1 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 OAJ21238.1 - 2.7e-12 46.9 0.0 1.4e-09 38.0 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 OAJ21238.1 - 1.2e-11 44.2 0.0 9.5e-09 35.0 0.0 3.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 OAJ21238.1 - 7e-05 22.9 0.0 0.0035 17.4 0.0 3.2 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 OAJ21238.1 - 0.027 13.6 0.0 0.78 8.9 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein Mis14 PF08641.7 OAJ21239.1 - 0.0027 17.7 1.3 0.0027 17.7 0.9 1.6 2 0 0 2 2 2 1 Kinetochore protein Mis14 like RNA_pol_Rpb2_6 PF00562.23 OAJ21240.1 - 1.4e-122 409.2 0.0 2e-122 408.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 OAJ21240.1 - 4.4e-57 192.2 0.2 7e-57 191.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 OAJ21240.1 - 1.3e-33 116.0 0.2 2.6e-33 115.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 OAJ21240.1 - 2.3e-26 91.8 0.0 6.6e-26 90.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 OAJ21240.1 - 6.1e-23 80.4 0.3 1.5e-22 79.1 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 OAJ21240.1 - 7.6e-21 73.6 0.0 1.7e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 OAJ21240.1 - 7.3e-13 48.2 0.3 2.2e-12 46.7 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 OAJ21240.1 - 0.00051 18.5 0.1 0.00083 17.8 0.0 1.2 1 0 0 1 1 1 1 Baculovirus Y142 protein UQ_con PF00179.21 OAJ21241.1 - 3e-22 78.5 0.0 6.5e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 OAJ21241.1 - 0.0052 16.4 0.0 0.0099 15.5 0.0 1.4 1 0 0 1 1 1 1 UEV domain UBA PF00627.26 OAJ21241.1 - 0.03 14.1 0.0 0.082 12.7 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain IBR PF01485.16 OAJ21241.1 - 0.03 14.1 1.5 0.07 13.0 1.0 1.5 1 0 0 1 1 1 0 IBR domain BUD22 PF09073.5 OAJ21241.1 - 2.2 7.2 29.1 0.18 10.8 7.4 2.4 2 0 0 2 2 2 0 BUD22 Neur_chan_memb PF02932.11 OAJ21241.1 - 2.2 8.0 3.4 4.9 6.9 2.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WD40 PF00400.27 OAJ21242.1 - 2.9e-16 58.6 6.8 0.00041 20.1 0.0 5.8 5 1 0 5 5 5 4 WD domain, G-beta repeat OEP PF02321.13 OAJ21242.1 - 0.0045 16.5 0.1 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 Outer membrane efflux protein Sugar_tr PF00083.19 OAJ21281.1 - 6.7e-46 156.7 14.9 8.7e-46 156.4 10.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ21281.1 - 2.4e-24 85.7 25.0 1.7e-14 53.3 9.0 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Peptidase_S24 PF00717.18 OAJ21281.1 - 0.00012 21.6 0.2 0.00074 19.1 0.2 2.1 1 1 0 1 1 1 1 Peptidase S24-like SMN PF06003.7 OAJ21282.1 - 0.00026 20.1 0.1 0.00026 20.1 0.1 1.9 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 OAJ21282.1 - 0.0016 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Tudor domain PWWP PF00855.12 OAJ21282.1 - 0.0066 16.6 1.1 0.062 13.5 0.0 2.3 2 0 0 2 2 2 1 PWWP domain LBR_tudor PF09465.5 OAJ21282.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain MIP-T3 PF10243.4 OAJ21283.1 - 1.4 7.2 50.0 0.94 7.8 24.6 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 RVT_3 PF13456.1 OAJ21284.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like Trypsin_2 PF13365.1 OAJ21284.1 - 0.06 13.3 0.0 0.77 9.7 0.0 2.4 1 1 0 1 1 1 0 Trypsin-like peptidase domain UCH PF00443.24 OAJ21285.1 - 3e-48 164.2 0.0 4.6e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ21285.1 - 4.5e-21 75.5 0.0 3.9e-11 42.9 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 OAJ21285.1 - 6.3e-21 74.2 10.2 1.3e-18 66.8 1.1 3.2 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 OAJ21285.1 - 3.5e-19 68.0 0.2 4.7e-09 35.8 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Misat_Tub_SegII PF10644.4 OAJ21285.1 - 0.043 13.8 0.1 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain Radical_SAM PF04055.16 OAJ21286.1 - 8e-14 52.1 0.0 1.2e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily DUF1335 PF07056.6 OAJ21286.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) PAP1 PF08601.5 OAJ21286.1 - 1.6 8.3 7.1 2.3 7.8 4.9 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 ABC_tran PF00005.22 OAJ21287.1 - 1.7e-14 54.2 0.0 1.3e-13 51.3 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 OAJ21287.1 - 1.3e-07 31.8 0.8 0.00096 19.1 0.4 2.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAJ21287.1 - 0.0011 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 OAJ21287.1 - 0.0016 18.3 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 OAJ21287.1 - 0.0034 17.7 0.0 0.0049 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ21287.1 - 0.0061 16.2 0.1 0.018 14.8 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 OAJ21287.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAJ21287.1 - 0.012 14.9 0.1 0.046 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 OAJ21287.1 - 0.018 14.5 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Guanylate kinase SMC_N PF02463.14 OAJ21287.1 - 0.019 14.1 0.0 0.27 10.4 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SRPRB PF09439.5 OAJ21287.1 - 0.023 13.9 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DAP3 PF10236.4 OAJ21287.1 - 0.036 13.0 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 T2SE PF00437.15 OAJ21287.1 - 0.048 12.5 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 OAJ21287.1 - 0.078 12.8 0.1 0.16 11.8 0.0 1.7 2 1 0 2 2 1 0 AAA domain AAA_22 PF13401.1 OAJ21287.1 - 0.087 12.9 0.0 0.33 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 OAJ21287.1 - 0.091 12.6 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 OAJ21287.1 - 0.097 12.6 0.7 0.18 11.8 0.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 OAJ21287.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 OAJ21287.1 - 0.11 11.9 0.0 0.39 10.1 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 OAJ21287.1 - 0.13 11.7 0.1 0.63 9.4 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.1 OAJ21287.1 - 0.13 11.2 0.0 0.34 9.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 OAJ21287.1 - 0.13 13.0 0.4 0.34 11.7 0.0 1.8 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 OAJ21287.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 OAJ21287.1 - 0.16 11.0 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Rhomboid PF01694.17 OAJ21290.1 - 3.2e-20 72.6 1.2 5.9e-20 71.7 0.8 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.5 OAJ21290.1 - 0.0015 18.7 0.1 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) adh_short PF00106.20 OAJ21291.1 - 7.7e-14 51.9 0.0 1.3e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ21291.1 - 8.2e-05 22.3 0.1 0.00011 21.8 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAJ21291.1 - 0.00012 22.1 0.1 0.00028 20.9 0.1 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAJ21291.1 - 0.00042 19.8 0.0 0.0008 18.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 OAJ21291.1 - 0.00095 19.0 0.0 0.0047 16.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 OAJ21291.1 - 0.1 11.6 0.1 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HECT PF00632.20 OAJ21292.1 - 3.3e-96 322.1 0.0 4.2e-96 321.8 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PfkB PF00294.19 OAJ21293.1 - 4e-41 141.0 0.1 5.6e-41 140.6 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase RabGAP-TBC PF00566.13 OAJ21294.1 - 2.2e-49 167.8 0.0 4e-49 166.9 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Nucleo_P87 PF07267.6 OAJ21294.1 - 0.91 8.1 7.0 0.061 12.0 0.7 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Aldedh PF00171.17 OAJ21340.1 - 8.4e-147 489.2 0.4 9.5e-147 489.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SIS PF01380.17 OAJ21342.1 - 1.9e-62 208.6 0.1 2.8e-34 117.5 0.0 2.6 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 OAJ21342.1 - 1.7e-19 69.7 0.0 2.8e-18 65.7 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 OAJ21342.1 - 1.7e-18 66.8 0.0 3.2e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 OAJ21342.1 - 2.3e-13 49.9 0.0 4.6e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 OAJ21342.1 - 8.7e-07 27.8 0.0 1.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 OAJ21342.1 - 0.001 18.8 0.0 0.047 13.3 0.0 3.1 3 1 1 4 4 4 1 SIS domain Plasmid_Txe PF06769.8 OAJ21342.1 - 0.15 11.9 0.0 0.95 9.3 0.0 2.2 2 0 0 2 2 2 0 Plasmid encoded toxin Txe DUF1253 PF06862.7 OAJ21343.1 - 1.7e-128 428.8 0.0 2.6e-128 428.1 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1253) TFIIA PF03153.8 OAJ21343.1 - 0.06 13.2 7.9 0.12 12.3 5.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AICARFT_IMPCHas PF01808.13 OAJ21344.1 - 1.5e-104 349.4 0.2 1.9e-104 349.1 0.1 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 OAJ21344.1 - 1.3e-21 76.2 0.0 2.4e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain SET PF00856.23 OAJ21345.1 - 6.4e-06 26.5 0.0 0.049 13.9 0.0 2.6 2 0 0 2 2 2 2 SET domain BSP_II PF05432.6 OAJ21346.1 - 0.084 12.1 3.2 7.6 5.7 4.0 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) GATase_2 PF00310.16 OAJ21347.1 - 8.3e-31 106.9 0.0 5.7e-19 68.0 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 OAJ21347.1 - 4.2e-19 68.8 0.0 6.2e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 OAJ21347.1 - 6.9e-14 51.6 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 OAJ21347.1 - 1.3e-07 30.6 0.0 1.4e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS PF01380.17 OAJ21347.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 SIS domain Daxx PF03344.10 OAJ21348.1 - 0.002 16.7 7.4 0.0029 16.1 5.1 1.2 1 0 0 1 1 1 1 Daxx Family DUF3153 PF11353.3 OAJ21348.1 - 0.8 9.0 4.6 0.22 10.9 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) Nop14 PF04147.7 OAJ21348.1 - 5.8 4.6 14.6 9.3 4.0 10.1 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 OAJ21348.1 - 9.9 5.3 16.2 18 4.4 11.2 1.4 1 0 0 1 1 1 0 SDA1 Peptidase_M16 PF00675.15 OAJ21349.1 - 3.6e-41 140.3 0.3 2.6e-40 137.5 0.0 2.6 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 OAJ21349.1 - 5.3e-36 124.0 0.3 2.3e-20 73.0 0.0 4.1 4 0 0 4 4 4 2 Peptidase M16 inactive domain Coagulin PF02035.10 OAJ21349.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Coagulin TFIIA PF03153.8 OAJ21349.1 - 2.4 7.9 5.3 7.2 6.4 1.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit P16-Arc PF04699.9 OAJ21350.1 - 5.3e-48 162.8 0.0 5.9e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) zf-RING_2 PF13639.1 OAJ21351.1 - 0.091 12.6 0.5 8.7 6.2 0.1 2.4 2 0 0 2 2 2 0 Ring finger domain MSP1_C PF07462.6 OAJ21351.1 - 4.1 5.6 3.2 8.2 4.6 2.2 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus stn_TNFRSF12A PF12191.3 OAJ21352.1 - 0.49 10.4 4.7 0.53 10.3 3.3 1.1 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DAGK_cat PF00781.19 OAJ21353.1 - 3.4e-11 42.6 0.0 8.2e-11 41.4 0.0 1.6 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain FMO-like PF00743.14 OAJ21401.1 - 3.8e-18 64.9 0.0 1.8e-13 49.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 OAJ21401.1 - 6.7e-13 49.1 0.0 9.1e-12 45.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ21401.1 - 1.1e-05 25.3 1.9 0.00011 22.0 0.1 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAJ21401.1 - 0.00033 20.6 0.0 0.00083 19.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAJ21401.1 - 0.00083 18.3 0.0 0.025 13.4 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 OAJ21401.1 - 0.03 14.4 0.0 5.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF2244 PF10003.4 OAJ21401.1 - 0.12 11.7 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) RNA_pol_Rpc4 PF05132.9 OAJ21402.1 - 9.1e-19 67.7 0.0 9.1e-19 67.7 0.0 4.3 5 0 0 5 5 5 2 RNA polymerase III RPC4 Leo1 PF04004.8 OAJ21402.1 - 0.081 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Leo1-like protein Metal_resist PF13801.1 OAJ21403.1 - 0.0073 16.3 5.2 0.01 15.8 1.2 2.3 2 0 0 2 2 2 1 Heavy-metal resistance OEP PF02321.13 OAJ21403.1 - 0.057 13.0 0.2 0.057 13.0 0.1 2.0 2 0 0 2 2 2 0 Outer membrane efflux protein PRP38 PF03371.10 OAJ21404.1 - 1.2e-61 207.2 0.1 1.6e-61 206.9 0.1 1.1 1 0 0 1 1 1 1 PRP38 family APC_CDC26 PF10471.4 OAJ21405.1 - 0.15 12.8 4.1 0.22 12.2 2.8 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 ABM PF03992.11 OAJ21406.1 - 9.2e-08 32.0 0.1 1.1e-07 31.7 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABC_tran PF00005.22 OAJ21407.1 - 6.1e-33 114.0 0.0 1.3e-32 112.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 OAJ21407.1 - 7.6e-25 87.8 4.6 1.5e-24 86.9 3.2 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 OAJ21407.1 - 6e-06 26.4 0.0 0.00053 20.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ21407.1 - 0.00025 21.0 0.2 0.00084 19.3 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 OAJ21407.1 - 0.00048 19.3 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 OAJ21407.1 - 0.0026 17.9 0.1 0.0099 16.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAJ21407.1 - 0.021 13.9 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin HpcH_HpaI PF03328.9 OAJ21408.1 - 2.4e-36 124.7 0.1 9.2e-36 122.7 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 OAJ21408.1 - 1.6e-08 33.7 0.0 0.0006 18.7 0.0 2.5 2 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PLDc_2 PF13091.1 OAJ21410.1 - 5.8e-17 61.6 0.0 1.3e-07 31.3 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.17 OAJ21410.1 - 3.4e-15 55.2 0.6 1.1e-06 28.1 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 OAJ21410.1 - 0.071 12.0 1.3 0.28 10.1 0.0 2.3 3 0 0 3 3 3 0 Archaeal transcriptional regulator TrmB Y_phosphatase PF00102.22 OAJ21411.1 - 6.3e-53 179.5 0.0 7.2e-46 156.4 0.0 2.8 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 OAJ21411.1 - 5.2e-05 23.5 0.0 0.00036 20.8 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 OAJ21411.1 - 0.0094 16.2 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 OAJ21411.1 - 0.013 15.0 0.1 0.027 14.0 0.1 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Dicty_REP PF05086.7 OAJ21411.1 - 0.25 9.0 2.2 0.48 8.1 1.6 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pyridoxal_deC PF00282.14 OAJ21412.1 - 7.1e-104 347.2 0.0 2.8e-102 341.9 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 OAJ21412.1 - 0.0014 17.7 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 OAJ21412.1 - 0.02 13.8 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_5 PF00266.14 OAJ21412.1 - 0.072 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Asp PF00026.18 OAJ21414.1 - 2.3e-47 161.7 0.1 7.5e-47 160.1 0.1 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 OAJ21414.1 - 1.4e-05 25.4 1.0 0.046 14.2 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 OAJ21414.1 - 0.091 12.3 0.0 0.22 11.0 0.0 1.7 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Arv1 PF04161.8 OAJ21415.1 - 1.3e-20 74.2 0.8 5.6e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 Arv1-like family eIF-5_eIF-2B PF01873.12 OAJ21415.1 - 1.7 8.3 3.0 0.76 9.4 0.6 1.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Dor1 PF04124.7 OAJ21463.1 - 0.083 11.3 5.8 0.31 9.4 0.6 2.6 3 0 0 3 3 3 0 Dor1-like family G-patch PF01585.18 OAJ21464.1 - 8.6e-06 25.4 0.2 2.1e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.3 OAJ21464.1 - 0.018 15.1 4.7 0.032 14.3 3.2 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF3449 PF11931.3 OAJ21464.1 - 0.061 12.8 0.2 0.061 12.8 0.1 2.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3449) WD40 PF00400.27 OAJ21467.1 - 2.5e-13 49.3 11.7 7.5e-07 28.8 0.2 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 OAJ21467.1 - 2e-05 22.9 0.1 0.00031 19.0 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 tRNA_Me_trans PF03054.11 OAJ21468.1 - 1.7e-93 313.0 0.0 4e-81 272.3 0.0 2.9 2 1 0 2 2 2 2 tRNA methyl transferase NAD_synthase PF02540.12 OAJ21468.1 - 4.1e-06 25.8 0.0 0.0009 18.2 0.0 2.2 2 0 0 2 2 2 2 NAD synthase ThiI PF02568.9 OAJ21468.1 - 0.00071 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 OAJ21468.1 - 0.046 13.2 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Borrelia_P83 PF05262.6 OAJ21470.1 - 0.012 13.9 3.1 0.014 13.6 2.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC37_N PF03234.9 OAJ21470.1 - 0.032 14.5 3.2 0.064 13.5 2.2 1.5 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF3450 PF11932.3 OAJ21470.1 - 0.057 12.6 4.8 0.091 12.0 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Uds1 PF15456.1 OAJ21470.1 - 0.061 13.3 5.0 0.1 12.5 3.5 1.4 1 0 0 1 1 1 0 Up-regulated During Septation V_ATPase_I PF01496.14 OAJ21470.1 - 0.15 9.9 0.4 0.19 9.5 0.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 OAJ21470.1 - 0.15 11.7 2.1 0.27 10.9 1.4 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 PA26 PF04636.8 OAJ21470.1 - 0.15 10.6 0.4 0.22 10.1 0.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) HAUS6_N PF14661.1 OAJ21470.1 - 0.32 10.3 3.6 0.49 9.6 2.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus APG6 PF04111.7 OAJ21470.1 - 0.96 8.4 6.9 1.4 7.8 4.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 OAJ21470.1 - 1.2 9.1 9.7 2.8 8.0 6.7 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Med21 PF11221.3 OAJ21470.1 - 1.6 8.7 10.3 2.7 7.9 7.1 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Bap31 PF05529.7 OAJ21470.1 - 2.3 7.6 8.6 3.7 6.9 6.0 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF1822 PF08852.6 OAJ21471.1 - 0.038 12.8 0.0 0.038 12.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1822) DNA_pol_phi PF04931.8 OAJ21471.1 - 0.046 11.5 16.1 0.065 11.0 11.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi MIP-T3 PF10243.4 OAJ21471.1 - 0.32 9.4 34.4 0.43 8.9 23.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 OAJ21471.1 - 0.4 9.1 23.0 0.54 8.6 15.9 1.1 1 0 0 1 1 1 0 Daxx Family Nop53 PF07767.6 OAJ21471.1 - 0.71 8.7 36.7 1.2 8.0 25.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Raftlin PF15250.1 OAJ21471.1 - 1.2 7.5 11.2 0.78 8.1 6.5 1.5 1 1 0 1 1 1 0 Raftlin TEX19 PF15553.1 OAJ21471.1 - 2.7 7.8 7.1 18 5.1 4.5 2.2 2 0 0 2 2 2 0 Testis-expressed protein 19 PPP4R2 PF09184.6 OAJ21471.1 - 3.7 7.0 21.9 6.8 6.1 15.2 1.4 1 0 0 1 1 1 0 PPP4R2 Nucleoplasmin PF03066.10 OAJ21471.1 - 3.8 7.0 21.5 10 5.6 14.9 1.7 1 0 0 1 1 1 0 Nucleoplasmin PLRV_ORF5 PF01690.12 OAJ21471.1 - 3.9 6.5 14.3 5.5 6.0 9.9 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein TRAP_alpha PF03896.11 OAJ21471.1 - 7 5.5 11.1 13 4.7 7.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pep3_Vps18 PF05131.9 OAJ21473.1 - 1.3e-43 147.9 0.0 8.4e-43 145.3 0.0 2.2 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 OAJ21473.1 - 7.2e-08 32.1 9.4 5.3e-07 29.3 0.4 2.8 2 1 0 2 2 2 2 Region in Clathrin and VPS zf-RING_5 PF14634.1 OAJ21473.1 - 0.0017 18.0 1.0 0.0041 16.8 0.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 OAJ21473.1 - 0.028 14.2 4.9 0.023 14.5 1.7 2.1 2 0 0 2 2 2 0 Ring finger domain Vps39_2 PF10367.4 OAJ21473.1 - 0.039 14.1 0.4 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Terminase_5 PF06056.7 OAJ21473.1 - 0.11 12.0 3.1 0.067 12.7 0.3 2.0 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) DUF2175 PF09943.4 OAJ21473.1 - 0.2 11.7 0.0 0.2 11.7 0.0 3.0 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2175) TPR_11 PF13414.1 OAJ21473.1 - 1.9 8.1 4.5 8 6.1 0.0 3.5 3 1 1 4 4 4 0 TPR repeat RRM_1 PF00076.17 OAJ21474.1 - 4e-19 68.0 0.1 6.1e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ21474.1 - 1.5e-10 40.9 0.0 2.1e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ21474.1 - 5.7e-05 22.8 0.0 8.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Secretin_N_2 PF07655.8 OAJ21475.1 - 0.4 11.1 5.9 4.5 7.7 0.1 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain Kelch_4 PF13418.1 OAJ21476.1 - 1.3e-42 143.3 12.9 2e-07 30.6 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 OAJ21476.1 - 1.8e-32 110.7 20.9 7.8e-08 32.2 0.3 7.7 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.20 OAJ21476.1 - 1.3e-29 101.4 3.9 8.8e-06 25.1 0.0 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 OAJ21476.1 - 5.1e-25 86.9 9.4 9.7e-07 28.6 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 OAJ21476.1 - 3e-22 77.4 8.8 4.4e-05 23.0 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 OAJ21476.1 - 1.2e-21 75.8 9.5 0.00029 20.8 0.0 6.3 5 1 1 6 6 6 5 Kelch motif PQQ_3 PF13570.1 OAJ21476.1 - 0.37 11.1 5.7 4.9 7.5 0.0 4.7 5 0 0 5 5 5 0 PQQ-like domain Adaptin_N PF01602.15 OAJ21477.1 - 4.3e-57 193.6 0.0 1.9e-33 115.5 0.0 3.2 3 0 0 3 3 3 3 Adaptin N terminal region HEAT_2 PF13646.1 OAJ21477.1 - 1.7e-08 34.6 12.0 3.1e-06 27.3 3.1 5.7 4 2 2 6 6 6 3 HEAT repeats HEAT PF02985.17 OAJ21477.1 - 0.00013 21.7 7.4 2.6 8.3 0.0 5.4 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 OAJ21477.1 - 0.0076 16.7 1.4 0.0076 16.7 1.0 6.1 7 1 1 8 8 8 2 HEAT-like repeat CTNNBL PF08216.6 OAJ21478.1 - 4.7e-27 93.7 0.2 4.7e-27 93.7 0.1 2.4 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 OAJ21478.1 - 0.0073 16.5 2.9 0.047 13.9 0.1 3.7 4 0 0 4 4 4 1 HEAT repeats Pox_E10 PF04805.7 OAJ21478.1 - 0.18 11.3 0.0 0.54 9.8 0.0 1.7 1 0 0 1 1 1 0 E10-like protein conserved region Arm PF00514.18 OAJ21478.1 - 0.26 11.1 2.3 1.5 8.8 0.1 2.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat AT_hook PF02178.14 OAJ21479.1 - 0.0067 15.9 21.0 0.063 12.9 3.1 3.1 2 0 0 2 2 2 2 AT hook motif DUF448 PF04296.8 OAJ21479.1 - 0.035 13.7 0.0 0.13 11.9 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF448) RVT_1 PF00078.22 OAJ21517.1 - 6.3e-25 87.7 0.0 8.6e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V-SNARE_C PF12352.3 OAJ21518.1 - 2.7e-13 49.7 0.3 6.3e-13 48.5 0.2 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 OAJ21518.1 - 3.7e-06 26.5 0.0 7.4e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Sec20 DSPn PF14671.1 OAJ21519.1 - 3.7e-31 107.9 0.0 2.8e-30 105.1 0.0 2.1 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 OAJ21519.1 - 3.5e-13 49.2 0.0 7.1e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAJ21519.1 - 2e-05 24.0 0.0 4.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 OAJ21519.1 - 0.0041 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Sld5 PF05916.6 OAJ21520.1 - 1e-18 67.6 0.4 1.8e-18 66.7 0.0 1.6 2 0 0 2 2 2 1 GINS complex protein FMN_dh PF01070.13 OAJ21521.1 - 1e-118 396.3 0.0 1.2e-118 395.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 OAJ21521.1 - 6.5e-21 73.9 0.6 1.2e-20 73.0 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 OAJ21521.1 - 1.1e-05 24.5 0.0 1.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 OAJ21521.1 - 0.00042 19.3 0.0 0.00081 18.3 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 OAJ21521.1 - 0.041 13.0 0.1 0.064 12.3 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Vps5 PF09325.5 OAJ21521.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Vps5 C terminal like Nop14 PF04147.7 OAJ21522.1 - 0.007 14.3 4.8 0.01 13.8 3.3 1.1 1 0 0 1 1 1 1 Nop14-like family DUF4228 PF14009.1 OAJ21522.1 - 0.063 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) TRAP_alpha PF03896.11 OAJ21522.1 - 1 8.3 6.0 1.9 7.4 3.4 1.8 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit dCMP_cyt_deam_1 PF00383.17 OAJ21523.1 - 5.1e-07 29.2 3.2 0.054 13.1 2.9 3.5 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region F-box-like PF12937.2 OAJ21524.1 - 0.00027 20.6 0.3 0.0081 15.8 0.0 3.1 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ21524.1 - 0.22 11.2 2.0 2.4 7.9 0.2 2.4 2 0 0 2 2 2 0 F-box domain Aldedh PF00171.17 OAJ21525.1 - 4e-180 599.0 1.0 4.6e-180 598.8 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Docking PF08990.6 OAJ21526.1 - 0.27 10.5 3.5 0.66 9.2 2.4 1.6 1 0 0 1 1 1 0 Erythronolide synthase docking Cellulase PF00150.13 OAJ21527.1 - 6.9e-13 48.4 8.9 2.1e-12 46.8 6.2 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.17 OAJ21528.1 - 4.7e-18 64.5 0.0 9.7e-17 60.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ21528.1 - 7.3e-13 48.3 0.0 5e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ21528.1 - 1.1e-11 44.4 0.0 1.5e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 OAJ21528.1 - 0.054 13.1 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 DbpA RNA binding domain OB_RNB PF08206.6 OAJ21528.1 - 0.11 12.0 0.2 0.39 10.2 0.2 1.8 1 1 0 1 1 1 0 Ribonuclease B OB domain RA PF00788.18 OAJ21529.1 - 2.2e-15 56.9 0.0 4.3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 OAJ21529.1 - 5.6e-14 51.2 0.4 1.7e-06 27.2 0.0 3.1 3 0 0 3 3 3 2 SH3 domain SAM_2 PF07647.12 OAJ21529.1 - 6e-10 38.8 0.0 9.3e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 OAJ21529.1 - 1.2e-09 37.5 1.8 2.5e-06 26.8 0.0 2.9 2 1 0 2 2 2 2 Variant SH3 domain SAM_1 PF00536.25 OAJ21529.1 - 2.6e-09 37.1 0.0 3.9e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 OAJ21529.1 - 1.1e-08 34.5 5.3 0.00033 20.1 0.1 2.8 3 0 0 3 3 3 2 Variant SH3 domain SAM_PNT PF02198.11 OAJ21529.1 - 0.27 11.0 0.0 1 9.1 0.0 1.8 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain Stm1_N PF09598.5 OAJ21530.1 - 0.44 11.2 4.2 0.93 10.2 2.9 1.6 1 0 0 1 1 1 0 Stm1 TFIIA PF03153.8 OAJ21531.1 - 0.14 12.0 10.1 1.9 8.2 5.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NAP PF00956.13 OAJ21532.1 - 1.1e-31 109.7 0.7 3.1e-31 108.3 0.5 1.6 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) DUF4611 PF15387.1 OAJ21532.1 - 4.9 7.3 8.4 0.44 10.7 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) TFIIE_beta PF02186.10 OAJ21534.1 - 0.00062 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 TFIIE beta subunit core domain PIP5K PF01504.13 OAJ21574.1 - 9.7e-44 149.3 0.0 1.4e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF1399 PF07173.7 OAJ21575.1 - 1.3e-14 54.6 1.4 7.3e-13 48.9 0.1 3.4 2 1 2 4 4 4 1 Protein of unknown function (DUF1399) DUF4301 PF14134.1 OAJ21575.1 - 0.18 10.3 0.0 0.27 9.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) RAP-1 PF03085.10 OAJ21576.1 - 0.34 10.2 5.1 0.61 9.3 3.6 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CDC50 PF03381.10 OAJ21577.1 - 5.3e-72 242.2 0.0 7e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF1049 PF06305.6 OAJ21577.1 - 1.9 8.0 4.1 0.64 9.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) ACOX PF01756.14 OAJ21578.1 - 1.5e-21 76.6 0.0 3e-15 56.0 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 OAJ21578.1 - 5.3e-19 68.7 0.1 1.1e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 OAJ21578.1 - 2.9e-09 36.3 0.7 7.4e-09 34.9 0.5 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 OAJ21578.1 - 5.8e-08 32.9 0.0 2.4e-07 30.9 0.0 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Sec7 PF01369.15 OAJ21579.1 - 2.2e-61 206.8 0.0 4.3e-61 205.9 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 OAJ21579.1 - 0.0001 21.7 4.9 0.1 11.9 0.8 4.0 2 1 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal F-box-like PF12937.2 OAJ21580.1 - 0.026 14.2 1.0 0.072 12.8 0.1 2.2 2 0 0 2 2 2 0 F-box-like GWT1 PF06423.7 OAJ21581.1 - 4.3e-32 111.0 0.0 2.4e-21 76.2 0.0 2.7 2 0 0 2 2 2 2 GWT1 UDPGT PF00201.13 OAJ21582.1 - 8.1e-15 54.3 0.1 1.7e-14 53.2 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase PolyA_pol PF01743.15 OAJ21583.1 - 6.5e-23 81.3 0.0 1.2e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 OAJ21583.1 - 0.0022 17.5 0.1 0.0052 16.3 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A ABC_tran PF00005.22 OAJ21631.1 - 1.2e-44 151.9 0.0 1.2e-29 103.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 OAJ21631.1 - 4.7e-26 91.8 6.9 4.7e-26 91.8 4.8 2.5 2 1 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 OAJ21631.1 - 3.4e-10 39.5 2.6 0.00033 19.9 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 OAJ21631.1 - 7.3e-07 29.3 3.3 0.00016 21.7 0.5 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 OAJ21631.1 - 2.1e-06 27.1 0.3 0.047 13.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 OAJ21631.1 - 2.3e-06 28.0 0.1 0.062 13.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 OAJ21631.1 - 1.1e-05 25.6 0.0 0.26 11.2 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 OAJ21631.1 - 0.00013 21.3 1.6 0.018 14.4 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAJ21631.1 - 0.0004 20.5 0.5 0.075 13.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 OAJ21631.1 - 0.00041 20.2 0.0 0.56 10.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SE PF00437.15 OAJ21631.1 - 0.00045 19.2 0.0 0.11 11.4 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 OAJ21631.1 - 0.00064 20.2 0.0 2.2 8.7 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 OAJ21631.1 - 0.00075 19.0 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_33 PF13671.1 OAJ21631.1 - 0.00078 19.3 0.0 0.29 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 OAJ21631.1 - 0.0021 17.9 0.3 0.021 14.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_14 PF13173.1 OAJ21631.1 - 0.0027 17.5 0.0 0.82 9.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain ABC_ATPase PF09818.4 OAJ21631.1 - 0.0032 16.1 0.5 0.89 8.0 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 OAJ21631.1 - 0.0043 16.2 0.0 0.79 8.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 OAJ21631.1 - 0.0066 16.2 0.1 0.81 9.4 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Arch_ATPase PF01637.13 OAJ21631.1 - 0.0066 16.1 0.3 0.57 9.8 0.0 2.8 2 1 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 OAJ21631.1 - 0.013 14.9 0.9 0.82 9.0 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain SbcCD_C PF13558.1 OAJ21631.1 - 0.015 15.1 0.4 4 7.4 0.0 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 OAJ21631.1 - 0.027 14.7 1.0 0.45 10.8 0.0 3.2 4 0 0 4 4 4 0 AAA domain Adeno_IVa2 PF02456.10 OAJ21631.1 - 0.041 12.5 0.0 0.5 8.9 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_30 PF13604.1 OAJ21631.1 - 0.046 13.2 1.1 0.85 9.1 0.1 3.0 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 OAJ21631.1 - 0.047 12.3 0.0 0.094 11.3 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 OAJ21631.1 - 0.048 13.3 0.0 3 7.5 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 OAJ21631.1 - 0.27 10.0 1.5 11 4.7 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_17 PF13207.1 OAJ21631.1 - 4.8 8.0 6.9 5.4 7.8 0.9 3.5 4 1 0 4 4 3 0 AAA domain HIG_1_N PF04588.8 OAJ21632.1 - 7.3e-19 67.2 0.3 1.1e-18 66.7 0.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region PGA2 PF07543.7 OAJ21632.1 - 0.15 11.8 2.7 0.22 11.3 1.9 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 CAF-1_p150 PF11600.3 OAJ21632.1 - 2.4 7.4 7.9 0.24 10.7 0.6 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Endotoxin_N PF03945.9 OAJ21633.1 - 1.8 7.8 0.1 3.1 7.1 0.1 1.2 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Metallopep PF12044.3 OAJ21634.1 - 1.6e-83 280.5 0.0 1.4e-35 122.5 0.0 3.1 3 0 0 3 3 3 3 Putative peptidase family Jacalin PF01419.12 OAJ21634.1 - 3.5e-19 68.9 0.0 0.0027 17.5 0.0 4.9 5 0 0 5 5 5 4 Jacalin-like lectin domain Peptidase_M66 PF10462.4 OAJ21634.1 - 0.0076 15.1 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase M66 Adeno_PX PF05829.7 OAJ21634.1 - 0.1 12.1 0.2 62 3.1 0.0 3.4 3 0 0 3 3 3 0 Adenovirus late L2 mu core protein (Protein X) PCNA_N PF00705.13 OAJ21635.1 - 9e-51 170.6 3.5 2.6e-50 169.2 0.9 2.2 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 OAJ21635.1 - 7.1e-43 145.5 0.0 3.7e-22 78.5 0.1 2.4 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 OAJ21635.1 - 4.3e-08 32.2 0.7 1.6e-06 27.0 0.5 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 OAJ21635.1 - 2.1e-05 23.7 0.0 8.3e-05 21.8 0.0 1.9 1 1 0 1 1 1 1 Rad9 Myc_N PF01056.13 OAJ21635.1 - 0.026 13.6 1.7 0.037 13.1 1.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region BSP_II PF05432.6 OAJ21635.1 - 0.041 13.1 3.2 0.066 12.4 2.2 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 OAJ21635.1 - 0.053 13.0 1.9 0.095 12.2 1.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 OAJ21635.1 - 0.078 13.2 4.8 0.16 12.2 3.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 OAJ21635.1 - 0.098 12.9 4.0 0.22 11.7 2.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LRS4 PF10422.4 OAJ21635.1 - 0.27 10.5 3.7 0.6 9.4 0.7 2.0 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 ABC_membrane PF00664.18 OAJ21636.1 - 9.2e-07 28.5 0.0 2.4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF2881 PF11087.3 OAJ21636.1 - 0.47 9.9 4.3 0.12 11.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2881) Abhydrolase_6 PF12697.2 OAJ21639.1 - 5.1e-30 105.0 0.0 8.2e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ21639.1 - 1.8e-15 56.9 0.0 2.6e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAJ21639.1 - 1.7e-09 37.6 0.0 2.6e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 OAJ21639.1 - 3.4e-09 36.5 0.0 1.1e-07 31.6 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAJ21639.1 - 3.9e-05 23.4 0.0 0.0001 22.1 0.0 1.7 2 0 0 2 2 1 1 Putative lysophospholipase Thioesterase PF00975.15 OAJ21639.1 - 0.0017 18.6 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydro_lipase PF04083.11 OAJ21639.1 - 0.0018 17.5 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 2 Partial alpha/beta-hydrolase lipase region Chlorophyllase PF07224.6 OAJ21639.1 - 0.0027 16.5 0.0 0.0038 16.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Peptidase_S9 PF00326.16 OAJ21639.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF676 PF05057.9 OAJ21639.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.15 OAJ21639.1 - 0.019 14.3 0.0 0.033 13.6 0.0 1.5 1 1 0 1 1 1 0 Putative esterase LCAT PF02450.10 OAJ21639.1 - 0.031 13.2 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.8 OAJ21639.1 - 0.04 13.4 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 OAJ21639.1 - 0.062 11.5 0.0 2.8 6.1 0.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.2 OAJ21639.1 - 0.12 11.1 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF1343 PF07075.6 OAJ21639.1 - 0.22 10.3 0.2 0.44 9.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1343) zf-RING_2 PF13639.1 OAJ21642.1 - 5.3e-08 32.5 1.1 2.2e-07 30.5 0.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 OAJ21642.1 - 3.8e-06 26.5 1.4 1.6e-05 24.5 0.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ21642.1 - 1e-05 25.1 0.8 2.9e-05 23.7 0.1 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 OAJ21642.1 - 7e-05 22.7 0.3 7e-05 22.7 0.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ21642.1 - 7.7e-05 22.2 0.1 7.7e-05 22.2 0.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 OAJ21642.1 - 0.0023 18.0 0.1 0.0061 16.6 0.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 OAJ21642.1 - 0.0027 17.3 0.2 0.0027 17.3 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 OAJ21643.1 - 3.4e-47 156.7 26.8 1.4e-09 37.4 0.2 8.7 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 OAJ21643.1 - 1.1e-10 41.0 0.2 2.5e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 OAJ21643.1 - 5.3e-09 34.7 8.2 0.6 8.1 0.1 5.3 2 1 3 5 5 5 5 Nucleoporin Nup120/160 PQQ_3 PF13570.1 OAJ21643.1 - 7.4e-05 22.8 6.0 4.5 7.6 0.0 6.2 5 1 1 6 6 6 2 PQQ-like domain F-box PF00646.28 OAJ21643.1 - 0.00031 20.2 0.1 0.00062 19.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain Abhydrolase_5 PF12695.2 OAJ21644.1 - 0.00017 21.3 0.0 0.00035 20.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAJ21644.1 - 0.023 14.2 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 OAJ21644.1 - 0.024 14.4 0.0 0.044 13.6 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_L14 PF00238.14 OAJ21644.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L14p/L23e Ndr PF03096.9 OAJ21644.1 - 0.17 10.3 0.0 0.47 8.8 0.0 1.6 2 0 0 2 2 2 0 Ndr family Transposase_21 PF02992.9 OAJ21691.1 - 0.0026 16.8 0.1 0.0044 16.1 0.1 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Herpes_UL14 PF03580.9 OAJ21691.1 - 0.012 15.3 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Nop53 PF07767.6 OAJ21692.1 - 0.00056 19.0 13.7 0.00096 18.2 9.5 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) YL1 PF05764.8 OAJ21692.1 - 0.0067 16.0 11.3 0.012 15.2 7.9 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Glypican PF01153.14 OAJ21692.1 - 0.47 8.9 3.2 0.58 8.6 2.2 1.1 1 0 0 1 1 1 0 Glypican XAP5 PF04921.9 OAJ21692.1 - 0.98 8.9 8.2 1.6 8.2 5.7 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator CDC45 PF02724.9 OAJ21692.1 - 6.1 4.7 9.5 8.3 4.3 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Aa_trans PF01490.13 OAJ21693.1 - 2.2e-30 105.4 31.8 2.6e-30 105.2 22.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PsbI PF02532.9 OAJ21693.1 - 0.021 14.4 2.2 0.11 12.1 1.5 2.3 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) LMF1 PF06762.9 OAJ21694.1 - 0.036 12.8 2.7 0.045 12.5 1.8 1.3 1 0 0 1 1 1 0 Lipase maturation factor CbiQ PF02361.11 OAJ21694.1 - 1.8 8.0 18.4 3 7.3 12.8 1.4 1 0 0 1 1 1 0 Cobalt transport protein Pkinase PF00069.20 OAJ21695.1 - 2.7e-14 52.9 0.0 3.7e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ21695.1 - 1.7e-07 30.5 0.0 2.2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase zf-C3HC4_3 PF13920.1 OAJ21696.1 - 1.4 8.6 9.0 0.2 11.3 1.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ21696.1 - 3.5 7.4 9.9 2.3 8.0 1.7 2.3 2 0 0 2 2 2 0 zinc-RING finger domain MULE PF10551.4 OAJ21697.1 - 1e-18 67.2 0.0 2.5e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ21697.1 - 1.3e-06 27.2 0.0 1.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family DBD_Tnp_Mut PF03108.10 OAJ21697.1 - 5.5e-05 22.6 0.1 0.00019 20.9 0.0 2.0 2 0 0 2 2 2 1 MuDR family transposase Fis1_TPR_N PF14852.1 OAJ21697.1 - 0.11 11.7 0.0 0.32 10.3 0.0 1.7 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat TFIIA PF03153.8 OAJ21698.1 - 0.0012 18.7 27.7 0.0012 18.7 19.2 2.8 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 OAJ21698.1 - 2.7 6.0 65.6 0.0052 15.0 34.9 2.6 2 1 1 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal RBP_receptor PF14752.1 OAJ21698.1 - 3.1 6.0 4.8 4.5 5.4 3.4 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor Hid1 PF12722.2 OAJ21698.1 - 4 5.0 20.2 5.7 4.4 14.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.7 OAJ21698.1 - 7.4 6.3 18.5 19 5.0 12.8 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PLRV_ORF5 PF01690.12 OAJ21698.1 - 9.7 5.2 25.8 23 3.9 17.9 1.6 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DEAD PF00270.24 OAJ21699.1 - 2.9e-41 140.7 0.4 4.7e-41 140.0 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ21699.1 - 1e-23 82.9 0.1 2e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 OAJ21699.1 - 0.0013 17.8 0.1 0.0026 16.8 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit TPR_2 PF07719.12 OAJ21700.1 - 1e-06 28.2 7.2 3.5 7.7 0.0 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ21700.1 - 3.7e-06 26.7 17.7 0.021 14.7 0.0 5.5 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ21700.1 - 0.0026 17.3 0.9 3.9 7.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat UNC45-central PF11701.3 OAJ21700.1 - 0.0026 17.4 0.0 0.005 16.5 0.0 1.5 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central TPR_11 PF13414.1 OAJ21700.1 - 0.006 16.1 10.4 0.63 9.7 0.0 4.8 4 1 1 5 5 5 2 TPR repeat SNAP PF14938.1 OAJ21700.1 - 0.099 11.7 0.8 0.23 10.5 0.1 1.9 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 OAJ21700.1 - 1.1 9.5 12.6 15 6.0 0.0 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ21700.1 - 2.5 8.9 18.2 60 4.6 0.0 7.4 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ21700.1 - 6.8 7.3 9.0 12 6.6 0.1 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat SH3_1 PF00018.23 OAJ21702.1 - 2e-13 49.4 0.1 3.1e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ21702.1 - 3.8e-10 39.1 0.0 6.5e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ21702.1 - 4e-08 32.6 0.0 7.3e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 OAJ21702.1 - 0.055 13.6 0.5 0.27 11.4 0.1 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain TrbC PF04956.8 OAJ21703.1 - 9.4 6.3 14.9 1.1 9.3 0.2 4.4 4 0 0 4 4 4 0 TrbC/VIRB2 family Clp1 PF06807.9 OAJ21704.1 - 1.8e-05 24.6 0.0 7.3e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 OAJ21704.1 - 0.0072 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 OAJ21704.1 - 0.02 14.8 0.0 0.069 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 OAJ21704.1 - 0.034 13.6 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activat PF00158.21 OAJ21704.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 OAJ21704.1 - 0.088 12.6 0.2 3.1 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 OAJ21704.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAJ21704.1 - 0.21 11.7 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase WW PF00397.21 OAJ21753.1 - 0.0041 16.9 4.3 0.021 14.6 3.0 2.0 1 1 0 1 1 1 1 WW domain Med15 PF09606.5 OAJ21753.1 - 8.7 4.4 14.6 8.8 4.3 10.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_M16 PF00675.15 OAJ21754.1 - 6.5e-17 61.6 0.0 1.6e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 OAJ21754.1 - 1.4e-08 34.6 0.0 3.1e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain E1-E2_ATPase PF00122.15 OAJ21755.1 - 1.8e-14 53.3 0.0 5.2e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 OAJ21755.1 - 2.6e-13 50.5 0.1 7.5e-13 49.0 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ21755.1 - 1e-12 47.7 0.0 3.4e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 OAJ21755.1 - 1.9e-11 44.7 0.3 3.6e-05 24.2 0.0 4.4 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ21755.1 - 0.00057 19.5 0.9 0.0064 16.0 0.2 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase WD40 PF00400.27 OAJ21756.1 - 2.1e-06 27.3 0.6 0.015 15.1 0.1 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat Sugar_tr PF00083.19 OAJ21757.1 - 1.2e-44 152.6 18.2 1.3e-24 86.6 0.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ21757.1 - 6.3e-17 61.3 33.7 2.6e-08 32.9 8.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Acyltransferase PF01553.16 OAJ21759.1 - 2.4e-10 39.9 0.0 0.00024 20.5 0.0 2.5 2 0 0 2 2 2 2 Acyltransferase Nop14 PF04147.7 OAJ21759.1 - 1.1 7.0 6.5 2.1 6.1 4.5 1.4 1 0 0 1 1 1 0 Nop14-like family DDE_1 PF03184.14 OAJ21760.1 - 1.4e-32 112.5 0.0 2.2e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAJ21760.1 - 1.4e-10 40.8 0.1 7e-10 38.5 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain TMEM191C PF15194.1 OAJ21760.1 - 0.8 9.5 3.4 0.54 10.1 0.5 2.2 2 0 0 2 2 2 0 TMEM191C family VHS PF00790.14 OAJ21761.1 - 9.6e-20 70.6 0.0 2.1e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 OAJ21761.1 - 0.00012 21.9 0.9 0.00035 20.4 0.6 1.7 1 0 0 1 1 1 1 GAT domain Atrophin-1 PF03154.10 OAJ21761.1 - 0.0042 15.3 9.6 0.0042 15.3 6.6 1.7 2 0 0 2 2 2 1 Atrophin-1 family ATG11 PF10377.4 OAJ21762.1 - 4.5e-24 84.8 0.0 9.9e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein 11 Baculo_PEP_C PF04513.7 OAJ21762.1 - 6.5 6.5 18.6 1 9.2 0.2 4.5 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus MFS_1_like PF12832.2 OAJ21763.1 - 6.6e-19 67.4 0.2 6.6e-19 67.4 0.2 2.2 2 0 0 2 2 2 1 MFS_1 like family Histone PF00125.19 OAJ21812.1 - 4.3e-22 78.0 0.1 6.2e-22 77.5 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T PF15511.1 OAJ21812.1 - 0.0042 16.4 0.0 0.0048 16.1 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 OAJ21812.1 - 0.025 14.7 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinetochore component CENP-S CAMSAP_CH PF11971.3 OAJ21812.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain NOA36 PF06524.7 OAJ21813.1 - 8.3 5.5 7.4 13 4.9 5.1 1.2 1 0 0 1 1 1 0 NOA36 protein 3Beta_HSD PF01073.14 OAJ21814.1 - 1.8e-19 69.4 0.0 1.3e-18 66.6 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAJ21814.1 - 7.2e-17 61.6 0.0 1.1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ21814.1 - 3.5e-14 53.2 0.1 1.7e-13 50.9 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAJ21814.1 - 2.1e-11 43.2 0.0 1.9e-10 40.0 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 OAJ21814.1 - 6.2e-08 32.1 0.0 8.9e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 OAJ21814.1 - 2.7e-05 23.2 0.1 4.3e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 OAJ21814.1 - 0.00097 19.0 0.5 0.004 17.0 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_2 PF03446.10 OAJ21814.1 - 0.0046 16.8 0.0 0.028 14.2 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.5 OAJ21814.1 - 0.061 12.9 0.4 1.2 8.7 0.3 2.2 1 1 0 1 1 1 0 KR domain Transposase_21 PF02992.9 OAJ21815.1 - 2.1e-14 53.1 0.0 3.8e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ21815.1 - 1.5e-06 27.6 0.1 3e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) PBP1_TM PF14812.1 OAJ21815.1 - 0.00063 20.0 2.4 0.0071 16.6 1.5 2.5 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Trypan_PARP PF05887.6 OAJ21815.1 - 0.011 15.5 2.3 0.027 14.2 1.6 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TLP-20 PF06088.6 OAJ21815.1 - 0.22 11.1 1.3 0.49 10.0 0.9 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FRG2 PF15315.1 OAJ21815.1 - 0.92 9.4 8.5 0.36 10.7 3.6 2.1 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 Ribosomal_S8 PF00410.14 OAJ21818.1 - 2.2e-19 69.5 0.0 3.3e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 vATP-synt_AC39 PF01992.11 OAJ21819.1 - 7.6e-98 327.7 0.0 8.5e-98 327.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit SRP40_C PF05022.7 OAJ21821.1 - 9e-30 102.9 5.6 2.6e-29 101.5 3.9 1.9 1 0 0 1 1 1 1 SRP40, C-terminal domain Asp PF00026.18 OAJ21823.1 - 3.6e-73 246.5 0.4 5e-73 246.1 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ21823.1 - 4.7e-07 29.8 0.1 4.7e-07 29.8 0.1 2.5 4 0 0 4 4 4 1 Xylanase inhibitor N-terminal Lum_binding PF00677.12 OAJ21825.1 - 7.8e-27 92.9 0.0 1.2e-17 63.5 0.0 3.7 3 1 0 3 3 3 3 Lumazine binding domain Herpes_gI PF01688.12 OAJ21825.1 - 0.061 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I Epimerase PF01370.16 OAJ21826.1 - 4.5e-42 144.0 0.0 8.1e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 OAJ21826.1 - 7.1e-10 38.2 0.0 8.2e-06 24.9 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 OAJ21826.1 - 1.9e-09 36.8 0.0 4.3e-09 35.6 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 OAJ21826.1 - 3.6e-09 35.7 0.0 5.2e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 OAJ21826.1 - 1.5e-05 24.0 0.0 0.052 12.4 0.0 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 OAJ21826.1 - 0.00016 21.7 0.0 0.00036 20.5 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 OAJ21826.1 - 0.025 14.5 2.9 0.033 14.1 0.0 2.4 2 0 0 2 2 2 0 short chain dehydrogenase NmrA PF05368.8 OAJ21826.1 - 0.21 10.8 0.4 0.89 8.7 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family DUF410 PF04190.8 OAJ21827.1 - 4.1e-26 92.0 0.2 5.9e-18 65.3 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF410) Sld5 PF05916.6 OAJ21828.1 - 2.6e-05 24.4 0.0 5e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 GINS complex protein PRP1_N PF06424.7 OAJ21829.1 - 8.6e-44 149.0 2.9 8.6e-44 149.0 2.0 1.8 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 OAJ21829.1 - 3.4e-26 89.3 24.4 0.014 15.9 0.1 13.9 7 5 8 15 15 15 7 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ21829.1 - 1.8e-18 66.6 14.2 0.0096 16.2 0.0 8.9 7 2 1 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ21829.1 - 1.1e-17 64.1 14.5 0.0069 17.0 0.2 7.9 6 1 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ21829.1 - 5.6e-11 41.9 0.1 0.00024 20.6 0.0 6.5 6 1 0 7 7 7 1 TPR repeat TPR_2 PF07719.12 OAJ21829.1 - 4.1e-08 32.5 1.4 9.8 6.3 0.0 8.3 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ21829.1 - 1.6e-05 24.6 0.2 0.16 11.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Suf PF05843.9 OAJ21829.1 - 0.00088 19.0 0.0 1.2 8.7 0.0 4.6 6 1 0 6 6 6 1 Suppressor of forked protein (Suf) TPR_17 PF13431.1 OAJ21829.1 - 0.0022 18.0 0.0 31 5.1 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ21829.1 - 0.017 15.5 6.3 15 6.3 0.0 7.3 9 1 0 9 9 8 0 Tetratricopeptide repeat MIT PF04212.13 OAJ21829.1 - 0.02 14.7 0.3 0.56 10.1 0.0 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain NARP1 PF12569.3 OAJ21829.1 - 0.024 13.4 8.2 1.9 7.1 0.1 4.5 4 1 1 5 5 5 0 NMDA receptor-regulated protein 1 FAT PF02259.18 OAJ21829.1 - 0.047 12.6 11.9 0.24 10.3 0.3 3.9 3 1 0 3 3 3 0 FAT domain TPR_12 PF13424.1 OAJ21829.1 - 0.055 13.4 2.8 48 3.9 0.2 5.7 6 1 2 8 8 7 0 Tetratricopeptide repeat zf-DNL PF05180.7 OAJ21830.1 - 5.4e-29 99.7 0.0 8e-29 99.1 0.0 1.3 1 0 0 1 1 1 1 DNL zinc finger Ogr_Delta PF04606.7 OAJ21830.1 - 0.16 11.6 1.7 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Cyclin PF08613.6 OAJ21892.1 - 3.2e-14 53.5 0.4 1.3e-11 45.1 0.0 2.4 2 0 0 2 2 2 2 Cyclin Syntaxin-6_N PF09177.6 OAJ21893.1 - 5.9e-17 61.8 0.7 6.2e-16 58.5 0.0 2.2 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 OAJ21893.1 - 9.7e-09 34.7 1.2 9.7e-09 34.7 0.8 2.3 2 0 0 2 2 2 1 SNARE domain FliJ PF02050.11 OAJ21893.1 - 0.0007 19.6 2.5 0.019 15.0 0.3 2.6 2 1 1 3 3 3 1 Flagellar FliJ protein Use1 PF09753.4 OAJ21893.1 - 0.0026 17.2 0.0 0.0046 16.4 0.0 1.5 2 0 0 2 2 2 1 Membrane fusion protein Use1 HisKA_3 PF07730.8 OAJ21893.1 - 0.011 16.0 5.5 0.37 11.1 0.2 2.4 2 0 0 2 2 2 0 Histidine kinase DUF2046 PF09755.4 OAJ21893.1 - 0.023 13.6 1.8 0.96 8.2 0.5 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF812 PF05667.6 OAJ21893.1 - 0.099 11.1 1.1 5.5 5.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Sec34 PF04136.10 OAJ21893.1 - 0.11 12.2 0.0 0.86 9.2 0.0 2.1 2 0 0 2 2 2 0 Sec34-like family GP41 PF00517.12 OAJ21893.1 - 0.44 10.0 1.9 13 5.2 0.1 2.4 2 1 1 3 3 3 0 Retroviral envelope protein DUF848 PF05852.6 OAJ21893.1 - 0.77 9.6 4.2 1.4 8.7 0.7 2.2 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) G10 PF01125.12 OAJ21894.1 - 2.6e-53 179.4 7.2 4.8e-53 178.6 5.0 1.4 1 0 0 1 1 1 1 G10 protein ATP-grasp_4 PF13535.1 OAJ21894.1 - 1.1e-08 35.0 0.0 1.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain DHQ_synthase PF01761.15 OAJ21894.1 - 7.9e-05 21.7 0.0 0.00014 20.8 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase ATPgrasp_Ter PF15632.1 OAJ21894.1 - 0.0017 17.1 0.0 0.043 12.5 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Phage_integrase PF00589.17 OAJ21898.1 - 3.1e-05 23.7 0.0 7.5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family DUF2360 PF10152.4 OAJ21898.1 - 0.93 9.7 5.9 18 5.5 0.1 2.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) AMP-binding PF00501.23 OAJ21899.1 - 4.4e-72 242.7 0.0 5.6e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ21899.1 - 6.1e-08 33.4 0.2 1.4e-07 32.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ig_Tie2_1 PF10430.4 OAJ21899.1 - 0.038 14.3 0.0 0.087 13.1 0.0 1.5 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 Miro PF08477.8 OAJ21900.1 - 1.6e-26 93.1 0.0 1.4e-11 44.9 0.0 4.2 3 1 0 3 3 3 2 Miro-like protein EF_assoc_2 PF08356.7 OAJ21900.1 - 5.6e-23 80.5 0.0 1.6e-22 79.0 0.0 1.8 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 OAJ21900.1 - 3e-20 71.2 0.0 8.5e-20 69.8 0.0 1.8 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 OAJ21900.1 - 6.2e-16 58.2 0.0 0.00028 20.3 0.0 4.9 5 0 0 5 5 5 3 Ras family MMR_HSR1 PF01926.18 OAJ21900.1 - 2.2e-06 27.6 0.0 0.00028 20.8 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 OAJ21900.1 - 4.3e-06 26.8 0.0 0.066 13.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 OAJ21900.1 - 8.6e-06 25.8 0.7 0.02 14.8 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain EF-hand_7 PF13499.1 OAJ21900.1 - 1.2e-05 25.3 0.3 0.2 11.8 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair Dynamin_N PF00350.18 OAJ21900.1 - 2.6e-05 24.0 0.1 0.27 11.0 0.1 2.5 2 0 0 2 2 2 2 Dynamin family ABC_tran PF00005.22 OAJ21900.1 - 4.5e-05 23.7 0.1 0.03 14.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 OAJ21900.1 - 0.00013 21.3 0.2 0.043 13.3 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 OAJ21900.1 - 0.00023 20.3 0.2 0.0018 17.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 EF-hand_6 PF13405.1 OAJ21900.1 - 0.00039 20.0 6.4 0.08 12.8 0.1 3.1 3 0 0 3 3 2 2 EF-hand domain AIG1 PF04548.11 OAJ21900.1 - 0.00049 19.2 0.1 0.00082 18.5 0.1 1.3 1 0 0 1 1 1 1 AIG1 family NACHT PF05729.7 OAJ21900.1 - 0.00095 18.8 0.2 1.6 8.3 0.0 2.4 2 0 0 2 2 2 2 NACHT domain MobB PF03205.9 OAJ21900.1 - 0.0012 18.5 0.1 0.029 14.0 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 OAJ21900.1 - 0.0067 16.3 0.2 2.9 7.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 OAJ21900.1 - 0.012 15.8 0.1 0.78 9.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 OAJ21900.1 - 0.012 15.4 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 OAJ21900.1 - 0.013 14.4 0.2 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 OAJ21900.1 - 0.018 14.5 0.1 4.6 6.6 0.1 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.13 OAJ21900.1 - 0.021 13.8 0.0 0.075 12.0 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_18 PF13238.1 OAJ21900.1 - 0.021 15.1 0.4 0.8 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 OAJ21900.1 - 0.022 14.2 0.0 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 OAJ21900.1 - 0.024 15.4 0.0 2.8 8.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 OAJ21900.1 - 0.026 14.0 0.1 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 OAJ21900.1 - 0.041 13.4 0.3 22 4.5 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein EF-hand_1 PF00036.27 OAJ21900.1 - 0.042 13.1 9.2 0.35 10.2 0.1 3.5 4 0 0 4 4 3 0 EF hand cobW PF02492.14 OAJ21900.1 - 0.042 13.2 0.1 4.7 6.6 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 OAJ21900.1 - 0.047 13.8 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 OAJ21900.1 - 0.051 13.2 0.1 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase Viral_helicase1 PF01443.13 OAJ21900.1 - 0.065 12.7 0.0 5.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 OAJ21900.1 - 0.11 11.9 0.1 3.8 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 OAJ21900.1 - 0.17 11.3 0.1 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase Arf PF00025.16 OAJ21900.1 - 0.27 10.4 0.0 4.3 6.5 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_23 PF13476.1 OAJ21900.1 - 0.29 11.4 0.3 13 6.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain EF-hand_10 PF14788.1 OAJ21900.1 - 0.35 10.5 0.4 1.2 8.8 0.0 1.9 2 0 0 2 2 2 0 EF hand NB-ARC PF00931.17 OAJ21900.1 - 0.36 9.6 0.0 5.8 5.6 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.12 OAJ21900.1 - 0.45 10.2 0.2 8.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_21 PF13304.1 OAJ21900.1 - 0.48 10.3 0.0 18 5.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.1 OAJ21900.1 - 0.58 9.8 1.2 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair Macoilin PF09726.4 OAJ21900.1 - 0.58 8.3 5.1 0.18 10.0 0.5 2.1 2 0 0 2 2 2 0 Transmembrane protein EF-hand_5 PF13202.1 OAJ21900.1 - 7 6.1 11.9 0.16 11.3 0.1 3.0 3 0 0 3 3 2 0 EF hand Ras PF00071.17 OAJ21901.1 - 3.6e-62 208.5 0.1 4.2e-62 208.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ21901.1 - 5.5e-20 72.0 0.0 7.6e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ21901.1 - 2.1e-12 46.6 0.0 2.8e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 OAJ21901.1 - 1.2e-06 28.4 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAJ21901.1 - 1.9e-05 24.2 0.1 7.3e-05 22.2 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 OAJ21901.1 - 9e-05 22.6 0.0 0.00031 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 OAJ21901.1 - 0.002 17.3 0.1 0.0046 16.1 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 OAJ21901.1 - 0.0047 16.1 0.0 0.0068 15.6 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_15 PF13175.1 OAJ21901.1 - 0.015 14.4 0.0 0.018 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.1 OAJ21901.1 - 0.017 15.1 0.5 0.047 13.6 0.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 OAJ21901.1 - 0.031 13.7 0.0 0.088 12.2 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 OAJ21901.1 - 0.034 13.3 0.0 0.082 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 OAJ21901.1 - 0.035 14.3 0.1 0.06 13.6 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 OAJ21901.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 OAJ21901.1 - 0.07 12.8 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 OAJ21901.1 - 0.11 12.4 0.1 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2420 PF10336.4 OAJ21902.1 - 1.4e-08 34.2 0.0 2.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) RCC1 PF00415.13 OAJ21903.1 - 5.6e-15 55.2 6.6 0.0055 16.8 0.0 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.1 OAJ21903.1 - 7.3e-11 41.9 0.6 6.4e-08 32.6 0.2 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) BTB PF00651.26 OAJ21903.1 - 1.4e-09 37.8 0.0 9.5e-05 22.3 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 OAJ21903.1 - 8.9e-08 32.4 0.4 0.00031 21.1 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ21903.1 - 3.2e-05 23.7 1.4 0.4 11.0 0.1 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 OAJ21903.1 - 3.3e-05 24.1 0.2 0.00019 21.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.1 OAJ21903.1 - 0.00064 19.2 15.6 0.0023 17.5 0.0 5.5 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat Ank PF00023.25 OAJ21903.1 - 0.0029 17.3 1.6 0.011 15.4 0.2 2.6 2 0 0 2 2 2 1 Ankyrin repeat THF_DHG_CYH PF00763.18 OAJ21904.1 - 9.5e-16 57.8 0.0 1.1e-06 28.6 0.0 2.3 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 OAJ21904.1 - 1.4e-13 50.2 0.1 3.9e-08 32.5 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.17 OAJ21904.1 - 0.039 12.7 0.4 0.057 12.2 0.3 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Shikimate_DH PF01488.15 OAJ21904.1 - 0.064 13.3 0.6 0.98 9.5 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase VKG_Carbox PF05090.9 OAJ21904.1 - 0.11 11.2 0.1 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase Prp19_bind PF06991.6 OAJ21905.1 - 4.7e-59 199.9 23.3 4.7e-59 199.9 16.1 2.0 2 0 0 2 2 2 1 Splicing factor, Prp19-binding domain zf-CCHC_2 PF13696.1 OAJ21905.1 - 0.2 11.1 0.8 0.46 10.0 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 OAJ21905.1 - 0.31 11.0 1.9 0.89 9.6 1.3 1.8 1 1 0 1 1 1 0 Zinc knuckle Rep_fac-A_C PF08646.5 OAJ21957.1 - 3e-55 185.9 2.2 6.2e-54 181.6 0.5 2.5 2 0 0 2 2 2 1 Replication factor-A C terminal domain Rep-A_N PF04057.7 OAJ21957.1 - 1.5e-24 85.6 0.0 3.5e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 OAJ21957.1 - 1.2e-13 50.7 0.4 1.6e-11 43.9 0.0 2.9 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 OAJ21957.1 - 0.00011 22.2 0.2 0.0057 16.7 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function DUF223 F-box-like PF12937.2 OAJ21958.1 - 0.0016 18.1 0.7 0.0048 16.5 0.1 2.2 2 0 0 2 2 2 1 F-box-like AMP-binding PF00501.23 OAJ21959.1 - 1.4e-229 761.5 0.0 3.7e-81 272.6 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 OAJ21959.1 - 1.1e-100 336.3 0.5 1.3e-26 93.1 0.1 4.5 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 OAJ21959.1 - 4.1e-36 123.0 2.2 1e-07 32.1 0.0 5.0 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 OAJ21959.1 - 1.7e-11 44.8 0.7 0.0017 19.2 0.0 4.4 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 OAJ21959.1 - 0.035 14.4 1.5 9.9 6.5 0.0 3.3 3 0 0 3 3 3 0 HxxPF-repeated domain Transferase PF02458.10 OAJ21959.1 - 0.045 12.1 0.0 0.41 9.0 0.0 2.4 3 0 0 3 3 3 0 Transferase family Peptidase_M50B PF13398.1 OAJ21960.1 - 1.8e-54 184.1 15.4 2.3e-54 183.8 10.7 1.1 1 0 0 1 1 1 1 Peptidase M50B-like HATPase_c PF02518.21 OAJ21961.1 - 3e-30 104.1 0.1 8.8e-30 102.6 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAJ21961.1 - 8.9e-25 86.8 0.1 3.8e-24 84.8 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 OAJ21961.1 - 4.9e-20 71.3 0.1 1.7e-19 69.5 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 OAJ21961.1 - 2.2e-18 66.1 0.4 2.2e-18 66.1 0.3 2.3 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.1 OAJ21961.1 - 4e-17 62.4 0.0 2.5e-12 47.0 0.0 4.4 4 1 0 4 4 4 2 PAS domain PAS_4 PF08448.5 OAJ21961.1 - 2.1e-16 59.8 1.0 2.1e-07 30.9 0.0 4.8 4 0 0 4 4 4 3 PAS fold PAS PF00989.19 OAJ21961.1 - 5.4e-11 42.2 0.0 0.011 15.4 0.0 4.6 4 0 0 4 4 4 2 PAS fold HATPase_c_3 PF13589.1 OAJ21961.1 - 0.001 18.7 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.1 OAJ21961.1 - 0.21 11.8 0.0 8.4 6.7 0.0 3.1 3 0 0 3 3 3 0 PAS domain PWI PF01480.12 OAJ21962.1 - 7.4e-26 90.0 0.0 1.1e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 PWI domain Pkinase PF00069.20 OAJ21963.1 - 7.6e-63 212.0 0.0 1.1e-62 211.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ21963.1 - 2.3e-28 98.9 0.0 4e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 OAJ21963.1 - 1e-07 32.3 0.1 1e-07 32.3 0.0 2.8 2 2 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.9 OAJ21963.1 - 0.003 16.6 0.0 0.0058 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ21963.1 - 0.15 10.9 0.1 0.88 8.4 0.0 2.2 2 1 0 2 2 2 0 Kinase-like UPF0506 PF11703.3 OAJ21964.1 - 9.2 6.3 11.9 5.2 7.1 3.0 2.2 1 1 1 2 2 2 0 UPF0506 MDFI PF15316.1 OAJ21965.1 - 1 9.3 6.4 1.1 9.1 4.4 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Lir1 PF07207.6 OAJ21965.1 - 1.9 8.6 12.7 2.5 8.3 8.8 1.2 1 0 0 1 1 1 0 Light regulated protein Lir1 PIH1 PF08190.7 OAJ21965.1 - 9 5.6 6.7 10 5.4 4.6 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Plasmodium_Vir PF05795.6 OAJ21965.1 - 9.4 5.3 7.2 11 5.0 5.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pkinase PF00069.20 OAJ22014.1 - 6.5e-33 113.9 0.0 3e-32 111.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ22014.1 - 4.6e-09 35.7 0.0 1.9e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ22014.1 - 0.15 10.9 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like CtIP_N PF10482.4 OAJ22015.1 - 0.0014 18.3 3.3 0.0023 17.7 2.3 1.2 1 0 0 1 1 1 1 Tumour-suppressor protein CtIP N-terminal domain TMF_TATA_bd PF12325.3 OAJ22015.1 - 0.015 14.9 4.6 0.024 14.3 3.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 OAJ22015.1 - 0.038 12.9 4.3 0.059 12.3 3.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF904 PF06005.7 OAJ22015.1 - 0.42 10.9 6.2 0.74 10.1 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Pro_isomerase PF00160.16 OAJ22016.1 - 1.4e-44 152.0 0.2 2.4e-44 151.2 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Xpo1 PF08389.7 OAJ22016.1 - 4.6e-14 52.5 0.0 2.4e-13 50.2 0.0 2.3 2 0 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.1 OAJ22016.1 - 0.0014 18.8 0.7 0.006 16.8 0.1 2.4 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 OAJ22016.1 - 0.003 17.4 0.1 0.12 12.4 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.18 OAJ22016.1 - 0.012 15.3 0.1 0.074 12.9 0.1 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF3295 PF11702.3 OAJ22017.1 - 3.4e-11 42.8 2.5 3.4e-11 42.8 1.7 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF3295) EPL1 PF10513.4 OAJ22018.1 - 1.4e-19 70.9 0.0 1.4e-19 70.9 0.0 5.0 5 1 0 5 5 5 1 Enhancer of polycomb-like Glyco_hydro_16 PF00722.16 OAJ22019.1 - 8e-07 28.5 0.1 1.8e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 XPA_C PF05181.7 OAJ22020.1 - 0.14 11.7 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 XPA protein C-terminus MarC PF01914.12 OAJ22020.1 - 0.42 9.7 1.0 0.9 8.6 0.7 1.5 1 0 0 1 1 1 0 MarC family integral membrane protein ISG65-75 PF11727.3 OAJ22020.1 - 0.46 9.4 12.2 0.76 8.7 8.4 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein NARP1 PF12569.3 OAJ22020.1 - 5.9 5.5 14.5 11 4.6 10.1 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peroxidase_2 PF01328.12 OAJ22021.1 - 2.4e-15 56.0 0.9 7.8e-15 54.3 0.6 1.7 1 1 0 1 1 1 1 Peroxidase, family 2 Solute_trans_a PF03619.11 OAJ22022.1 - 5.1e-77 258.8 21.9 6.4e-77 258.5 15.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha BTV_NS2 PF04514.7 OAJ22022.1 - 0.5 9.2 1.9 0.91 8.3 1.3 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Abhydrolase_3 PF07859.8 OAJ22023.1 - 3.9e-33 114.8 0.1 5.1e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ22023.1 - 6.2e-06 26.0 0.0 1.3e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ22023.1 - 5.6e-05 22.4 0.0 0.14 11.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 OAJ22023.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 OAJ22023.1 - 0.0034 17.3 1.7 0.0073 16.2 1.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 OAJ22023.1 - 0.0044 16.7 0.0 0.025 14.2 0.0 2.1 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.3 OAJ22023.1 - 0.0046 16.3 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DLH PF01738.13 OAJ22023.1 - 0.074 12.3 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family HECT_2 PF09814.4 OAJ22024.1 - 1.5e-29 102.8 0.0 1.7e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Nudix_N_2 PF14803.1 OAJ22024.1 - 0.34 10.6 2.0 0.59 9.8 0.1 2.4 3 0 0 3 3 3 0 Nudix N-terminal Mannosyl_trans3 PF11051.3 OAJ22067.1 - 2.8e-11 43.2 0.0 3.4e-10 39.7 0.0 2.4 1 1 0 1 1 1 1 Mannosyltransferase putative Gag_p30 PF02093.11 OAJ22067.1 - 0.008 15.4 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Gag P30 core shell protein XAP5 PF04921.9 OAJ22068.1 - 2.8e-93 311.8 10.9 2.8e-93 311.8 7.6 2.4 1 1 1 2 2 2 1 XAP5, circadian clock regulator Mucin PF01456.12 OAJ22068.1 - 0.16 11.6 10.2 0.25 11.1 7.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein MOZART1 PF12554.3 OAJ22069.1 - 1.4e-15 56.4 0.1 1.7e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated UPF0181 PF03701.9 OAJ22069.1 - 0.097 11.9 0.2 0.19 11.0 0.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0181) Ribul_P_3_epim PF00834.14 OAJ22070.1 - 1.9e-68 229.5 0.0 2.2e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 OAJ22070.1 - 0.00067 19.2 0.0 0.0026 17.2 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain PcrB PF01884.12 OAJ22070.1 - 0.074 12.2 0.1 0.32 10.2 0.0 1.9 1 1 1 2 2 2 0 PcrB family Abhydrolase_5 PF12695.2 OAJ22071.1 - 5.7e-16 58.5 0.1 9e-16 57.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ22071.1 - 2.3e-12 47.2 3.5 4.7e-12 46.2 2.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAJ22071.1 - 6.7e-11 42.1 0.1 9.3e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAJ22071.1 - 0.0031 16.7 0.2 0.015 14.5 0.1 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 OAJ22071.1 - 0.0033 16.9 0.1 0.01 15.4 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 OAJ22071.1 - 0.026 14.7 0.1 0.053 13.7 0.1 1.5 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.3 OAJ22071.1 - 0.036 13.9 0.1 0.33 10.8 0.0 2.4 2 0 0 2 2 2 0 Putative lysophospholipase Nol1_Nop2_Fmu PF01189.12 OAJ22072.1 - 7.4e-93 310.9 0.0 9.6e-93 310.6 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 OAJ22072.1 - 0.00021 21.3 0.0 0.0004 20.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 OAJ22072.1 - 0.00024 20.7 0.0 0.0004 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 OAJ22072.1 - 0.00052 19.6 0.0 0.00092 18.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.14 OAJ22072.1 - 0.0015 18.1 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) XPG_I PF00867.13 OAJ22073.1 - 4.6e-16 58.6 0.0 2.3e-15 56.4 0.0 2.1 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 OAJ22073.1 - 4.1e-06 26.9 0.0 1.3e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain PP2C PF00481.16 OAJ22075.1 - 5e-34 117.8 0.0 1.4e-31 109.8 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C Radical_SAM PF04055.16 OAJ22076.1 - 1.5e-16 60.9 0.4 1e-15 58.2 0.1 2.2 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 OAJ22076.1 - 1.5e-10 40.9 0.0 4.2e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAJ22076.1 - 0.024 14.7 0.1 0.31 11.1 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ22076.1 - 0.085 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein RPA_C PF08784.6 OAJ22077.1 - 1.8e-09 37.9 0.1 1.8e-09 37.9 0.1 2.2 3 0 0 3 3 3 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 OAJ22077.1 - 2.4e-09 36.9 0.1 4e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HTH_20 PF12840.2 OAJ22077.1 - 0.00052 19.7 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain BOF PF04076.8 OAJ22077.1 - 0.055 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein DOMON PF03351.12 OAJ22077.1 - 0.068 13.1 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 DOMON domain HTH_27 PF13463.1 OAJ22077.1 - 0.12 12.6 0.0 0.4 11.0 0.0 2.0 1 0 0 1 1 1 0 Winged helix DNA-binding domain 4F5 PF04419.9 OAJ22079.1 - 5.8e-10 39.7 8.5 5.8e-10 39.7 5.9 2.2 2 0 0 2 2 2 1 4F5 protein family Phage_tail_2 PF06199.6 OAJ22079.1 - 0.078 13.0 0.1 0.082 12.9 0.1 1.1 1 0 0 1 1 1 0 Phage major tail protein 2 CdhC PF03598.10 OAJ22079.1 - 0.11 10.9 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit Chs3p PF12271.3 OAJ22080.1 - 1.3e-30 106.4 17.9 5.5e-29 101.0 12.4 2.0 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit Soyouz_module PF14313.1 OAJ22080.1 - 9.9e-05 21.8 0.5 0.00052 19.5 0.0 2.0 2 0 0 2 2 2 1 N-terminal region of Paramyxovirinae phosphoprotein (P) PsbX PF06596.6 OAJ22080.1 - 5 6.8 8.0 1.1 9.0 0.2 3.2 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) Syja_N PF02383.13 OAJ22081.1 - 1.2e-72 244.4 0.0 2.4e-72 243.4 0.0 1.5 1 1 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 OAJ22081.1 - 1.3e-27 95.4 0.0 7.8e-27 92.9 0.0 2.0 2 0 0 2 2 2 1 Inositol phosphatase RRM_1 PF00076.17 OAJ22132.1 - 2.9e-34 116.5 0.1 4.2e-17 61.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ22132.1 - 1.2e-31 108.5 0.1 2e-15 56.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ22132.1 - 5.3e-10 38.9 0.1 0.0002 21.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ22132.1 - 0.027 14.3 0.0 6.7 6.6 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.1 OAJ22132.1 - 0.029 14.1 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Sec1 PF00995.18 OAJ22133.1 - 1.6e-148 495.8 0.0 1.8e-148 495.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family IFT20 PF14931.1 OAJ22133.1 - 0.12 12.2 0.4 0.23 11.3 0.3 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Methyltransf_16 PF10294.4 OAJ22134.1 - 2.3e-07 30.4 0.0 4e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 OAJ22134.1 - 5.6e-06 26.9 0.0 9.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 OAJ22134.1 - 0.00024 20.3 0.0 0.00038 19.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 OAJ22134.1 - 0.0021 18.0 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ22134.1 - 0.045 13.4 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ22134.1 - 0.054 13.9 0.0 0.1 13.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ22134.1 - 0.058 12.9 0.0 0.68 9.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.13 OAJ22137.1 - 2.2e-11 43.6 0.1 1e-10 41.4 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 OAJ22137.1 - 8.5e-10 38.6 0.0 1.7e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 OAJ22137.1 - 3.7e-05 23.3 0.0 0.00015 21.3 0.0 2.0 1 1 0 1 1 1 1 DNA methylase N6_Mtase PF02384.11 OAJ22137.1 - 0.0041 16.2 0.0 0.012 14.7 0.0 1.8 1 1 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.10 OAJ22137.1 - 0.013 15.0 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Met_10 PF02475.11 OAJ22137.1 - 0.031 13.8 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Peptidase_M76 PF09768.4 OAJ22138.1 - 1.4e-48 164.6 0.0 2.2e-48 163.9 0.0 1.3 1 1 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 OAJ22138.1 - 0.0028 17.3 0.1 0.015 14.9 0.0 1.9 2 0 0 2 2 2 1 SprT-like family Ferritin_2 PF13668.1 OAJ22139.1 - 3e-47 159.9 4.5 4.6e-47 159.3 3.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain Ribosomal_L1 PF00687.16 OAJ22140.1 - 1.4e-23 83.4 0.0 3.8e-22 78.7 0.0 2.0 2 0 0 2 2 2 2 Ribosomal protein L1p/L10e family Lyase_1 PF00206.15 OAJ22141.1 - 5.6e-118 393.6 0.1 8.2e-118 393.1 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 OAJ22141.1 - 9.4e-20 70.4 0.0 2.9e-19 68.8 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.7 OAJ22141.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain GLTSCR1 PF15249.1 OAJ22142.1 - 4.4e-10 39.6 0.0 1.2e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Glioma tumor suppressor candidate region RNA_pol_Rpb2_6 PF00562.23 OAJ22143.1 - 1.7e-122 408.9 0.2 2.3e-117 392.0 0.1 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 OAJ22143.1 - 2.3e-65 219.3 0.2 3.6e-65 218.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 OAJ22143.1 - 2.1e-47 161.0 0.0 4e-47 160.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 OAJ22143.1 - 4e-28 97.4 0.1 1e-27 96.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 OAJ22143.1 - 7.4e-25 86.5 0.1 2.2e-24 85.0 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 OAJ22143.1 - 6.8e-24 83.4 0.1 1.7e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 OAJ22143.1 - 6.3e-19 67.6 0.1 1.3e-18 66.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF3635 PF12330.3 OAJ22144.1 - 1.3e-13 50.8 0.0 2.6e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) FG-GAP_2 PF14312.1 OAJ22144.1 - 0.017 15.1 0.0 0.047 13.7 0.0 1.8 1 0 0 1 1 1 0 FG-GAP repeat Nucleoplasmin PF03066.10 OAJ22144.1 - 0.031 13.8 6.6 0.074 12.5 4.5 1.6 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 OAJ22144.1 - 1.1 9.0 7.6 4.1 7.1 5.2 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal CWC25 PF12542.3 OAJ22145.1 - 3e-25 88.5 1.0 3e-25 88.5 0.7 3.6 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 OAJ22145.1 - 2.1e-13 50.0 12.2 2.1e-13 50.0 8.5 3.7 3 1 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR DEAD PF00270.24 OAJ22146.1 - 0.00078 18.9 0.0 0.0009 18.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Lipase_3 PF01764.20 OAJ22147.1 - 0.0003 20.4 0.0 0.00046 19.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Phage_integrase PF00589.17 OAJ22188.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DNA_pol_viral_C PF00336.13 OAJ22188.1 - 0.023 13.9 0.2 0.049 12.8 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Med26 PF08711.6 OAJ22189.1 - 7.1e-10 38.2 0.0 1.6e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain eIF-5_eIF-2B PF01873.12 OAJ22191.1 - 3.4e-41 139.7 0.1 5.3e-41 139.1 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 OAJ22191.1 - 1.8e-22 79.0 0.4 1.2e-21 76.4 0.1 2.5 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon DUF974 PF06159.8 OAJ22192.1 - 4.6e-38 131.0 0.0 1.3e-30 106.6 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF974) Transglut_C PF00927.17 OAJ22192.1 - 0.023 14.7 0.0 0.082 12.9 0.0 1.8 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain Nop14 PF04147.7 OAJ22193.1 - 1.1 7.0 12.5 1.5 6.6 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 OAJ22193.1 - 3.4 6.6 12.6 6.1 5.8 8.7 1.4 1 0 0 1 1 1 0 BUD22 Pro_isomerase PF00160.16 OAJ22194.1 - 3.4e-16 59.8 0.0 4.5e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_C50 PF03568.12 OAJ22194.1 - 0.21 10.2 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C50 Ins_beta PF03488.9 OAJ22195.1 - 0.057 13.2 0.8 0.057 13.2 0.6 2.2 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type R3H PF01424.17 OAJ22197.1 - 7.7e-12 44.7 0.8 3.9e-11 42.4 0.1 2.2 2 0 0 2 2 2 1 R3H domain RRM_6 PF14259.1 OAJ22197.1 - 8e-10 38.5 0.1 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ22197.1 - 1.3e-06 27.9 0.0 2.9e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ22197.1 - 4e-06 26.5 0.1 7.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAC PF01849.13 OAJ22198.1 - 1.8e-21 75.3 0.0 5.3e-21 73.9 0.0 1.8 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 OAJ22198.1 - 0.0074 16.1 0.0 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Striatin PF08232.7 OAJ22199.1 - 7.6e-40 136.3 0.0 1.4e-38 132.2 0.0 5.0 5 0 0 5 5 5 2 Striatin family WD40 PF00400.27 OAJ22199.1 - 1.5e-39 132.4 6.7 1.9e-07 30.7 0.4 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat adh_short_C2 PF13561.1 OAJ22200.1 - 3.5e-28 98.9 0.0 4e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ22200.1 - 4.3e-24 85.3 0.1 5.7e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ22200.1 - 2.7e-09 36.9 0.0 3.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 OAJ22200.1 - 0.0026 16.9 0.0 0.0031 16.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RAB3GAP2_N PF14655.1 OAJ22201.1 - 4.4 6.2 10.7 0.7 8.8 1.5 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Suf PF05843.9 OAJ22201.1 - 6.5 6.3 14.3 0.31 10.7 3.0 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) UPF0560 PF10577.4 OAJ22201.1 - 7.1 4.7 20.8 2.2 6.4 7.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 EPL1 PF10513.4 OAJ22201.1 - 9.8 6.3 11.8 4.9 7.3 2.4 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF1757 PF08560.5 OAJ22202.1 - 0.037 13.7 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) TctB PF07331.6 OAJ22202.1 - 0.13 11.8 2.7 0.22 11.1 0.4 2.1 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DEAD PF00270.24 OAJ22203.1 - 7.9e-41 139.3 1.6 7e-40 136.2 0.5 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ22203.1 - 2.9e-20 71.9 0.2 7.7e-20 70.5 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Pyridox_ox_2 PF12900.2 OAJ22203.1 - 5.3e-06 26.3 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase AAA_19 PF13245.1 OAJ22203.1 - 0.00014 21.5 0.1 0.0004 20.0 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 OAJ22203.1 - 0.00073 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 OAJ22203.1 - 0.027 14.0 0.1 0.094 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 OAJ22203.1 - 0.052 13.1 0.3 1.9 7.9 0.1 2.3 2 1 0 2 2 2 0 AAA domain CMS1 PF14617.1 OAJ22203.1 - 0.059 12.4 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.16 OAJ22203.1 - 0.061 12.6 0.1 0.079 12.2 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 OAJ22203.1 - 0.073 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Helicase MARVEL PF01284.18 OAJ22256.1 - 1.5e-06 28.1 8.8 2.3e-06 27.4 6.1 1.3 1 0 0 1 1 1 1 Membrane-associating domain Mito_carr PF00153.22 OAJ22258.1 - 0.027 14.1 0.5 2.2 8.0 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial carrier protein Methyltransf_23 PF13489.1 OAJ22259.1 - 5.6e-22 78.1 0.0 1.5e-21 76.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ22259.1 - 1.6e-15 57.3 0.0 6.2e-15 55.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ22259.1 - 6.1e-14 51.8 0.0 1.1e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ22259.1 - 4.5e-13 49.5 0.1 3.3e-12 46.7 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ22259.1 - 3.9e-12 46.7 0.0 7.9e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ22259.1 - 1.8e-07 31.2 1.1 4.3e-07 29.9 0.3 2.0 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 OAJ22259.1 - 1.2e-06 27.7 0.0 0.013 14.6 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 OAJ22259.1 - 6.3e-06 25.1 0.0 0.0044 15.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1698) PrmA PF06325.8 OAJ22259.1 - 0.00018 20.7 0.0 0.00038 19.6 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 OAJ22259.1 - 0.00023 21.4 0.0 0.00058 20.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 OAJ22259.1 - 0.0055 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ22259.1 - 0.0064 15.8 0.1 0.025 13.9 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase small domain NodS PF05401.6 OAJ22259.1 - 0.0085 15.5 0.0 3.1 7.1 0.0 2.2 2 0 0 2 2 2 2 Nodulation protein S (NodS) DREV PF05219.7 OAJ22259.1 - 0.02 13.7 0.0 0.064 12.1 0.0 1.7 2 0 0 2 2 2 0 DREV methyltransferase TPMT PF05724.6 OAJ22259.1 - 0.036 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.13 OAJ22259.1 - 0.052 12.6 0.0 0.37 9.8 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.7 OAJ22259.1 - 0.082 12.2 0.0 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Hydant_A_N PF05378.8 OAJ22260.1 - 5.1e-20 71.6 0.1 6.4e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region Peptidase_C1_2 PF03051.10 OAJ22262.1 - 2.3e-32 112.1 0.0 1.1e-29 103.2 0.0 2.0 2 0 0 2 2 2 2 Peptidase C1-like family Pectate_lyase_3 PF12708.2 OAJ22263.1 - 1.5e-69 234.6 5.5 2.9e-51 174.7 2.2 2.7 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 OAJ22263.1 - 0.00045 19.6 4.6 0.051 13.0 0.0 3.3 4 0 0 4 4 4 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 OAJ22263.1 - 0.0025 17.5 2.7 0.0099 15.6 1.9 2.1 1 0 0 1 1 1 1 Right handed beta helix region Trypan_PARP PF05887.6 OAJ22263.1 - 0.2 11.4 3.6 0.47 10.2 2.5 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.7 OAJ22263.1 - 0.66 7.8 9.7 0.94 7.3 6.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 OAJ22263.1 - 6.8 4.5 10.5 10 3.9 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Prok-TraM PF09228.5 OAJ22264.1 - 0.16 12.1 1.0 0.22 11.6 0.7 1.1 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Glyco_tran_28_C PF04101.11 OAJ22265.1 - 1.1e-22 80.4 0.0 1.8e-22 79.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain RVT_2 PF07727.9 OAJ22266.1 - 5.7e-36 123.7 0.0 7.2e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 OAJ22266.1 - 0.018 14.8 0.0 0.06 13.1 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase-like RAI16-like PF10257.4 OAJ22267.1 - 1.7e-57 194.9 0.0 7.3e-57 192.8 0.0 1.9 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein Sigma70_ner PF04546.8 OAJ22267.1 - 0.17 11.4 14.1 0.92 9.0 2.7 3.3 3 0 0 3 3 3 0 Sigma-70, non-essential region XAP5 PF04921.9 OAJ22267.1 - 1.2 8.7 3.1 2.4 7.6 2.1 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator Spt5_N PF11942.3 OAJ22267.1 - 2.5 8.7 23.2 1.3 9.6 5.9 3.5 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Prp19_bind PF06991.6 OAJ22267.1 - 7 5.8 9.7 0.85 8.8 3.4 1.7 2 0 0 2 2 2 0 Splicing factor, Prp19-binding domain RRN3 PF05327.6 OAJ22267.1 - 7.9 4.4 3.7 16 3.4 2.6 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TPR_10 PF13374.1 OAJ22268.1 - 4.3e-07 29.6 8.9 0.015 15.2 0.8 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ22268.1 - 8.1e-06 25.6 23.8 0.00038 20.3 2.4 6.7 6 1 3 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ22268.1 - 3.4e-05 23.4 9.4 1.3 9.1 1.5 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ22268.1 - 0.00082 19.8 13.4 2.2 9.1 0.0 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ22268.1 - 0.00087 18.8 3.4 0.91 9.2 0.0 3.6 4 0 0 4 4 2 2 TPR repeat TPR_17 PF13431.1 OAJ22268.1 - 0.0011 18.9 0.2 2.9 8.2 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 OAJ22268.1 - 0.0041 17.2 7.0 5 7.3 0.0 4.9 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 OAJ22268.1 - 0.0085 15.6 7.7 1.4 8.6 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ22268.1 - 0.03 14.0 7.8 8.5 6.4 0.0 5.3 4 1 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 OAJ22268.1 - 0.051 13.4 2.0 13 5.7 0.0 3.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.2 OAJ22268.1 - 0.062 13.1 0.2 0.41 10.4 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) YyzF PF14116.1 OAJ22268.1 - 0.081 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 YyzF-like protein TPR_19 PF14559.1 OAJ22268.1 - 0.12 12.7 16.5 13 6.2 0.5 6.4 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ22268.1 - 0.52 10.9 11.3 3 8.5 0.1 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ22268.1 - 7.5 7.3 18.5 17 6.2 0.0 5.4 6 1 0 6 6 4 0 Tetratricopeptide repeat RAI16-like PF10257.4 OAJ22269.1 - 4.2e-06 25.9 0.1 4.8e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein TPR_12 PF13424.1 OAJ22272.1 - 4e-06 26.6 10.7 2.2 8.2 0.0 7.2 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ22272.1 - 0.0031 18.0 38.0 11 6.9 0.0 12.3 10 4 3 13 13 13 2 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ22272.1 - 0.012 15.7 12.0 1.2e+02 3.2 0.0 8.2 8 0 0 8 8 8 0 Tetratricopeptide repeat PPR_3 PF13812.1 OAJ22272.1 - 0.021 15.0 0.0 1.3 9.4 0.0 4.2 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Mad3_BUB1_I PF08311.7 OAJ22272.1 - 0.039 13.7 3.5 0.25 11.1 0.2 3.9 4 1 0 4 4 4 0 Mad3/BUB1 homology region 1 HAT PF02184.11 OAJ22272.1 - 0.41 10.4 8.1 2.4 7.9 0.1 5.7 5 0 0 5 5 5 0 HAT (Half-A-TPR) repeat TPR_2 PF07719.12 OAJ22272.1 - 1.1 9.3 19.8 4.8 7.3 0.1 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Hus1 PF04005.7 OAJ22274.1 - 2.5e-72 243.3 0.1 3.7e-72 242.7 0.1 1.3 1 0 0 1 1 1 1 Hus1-like protein DUF1681 PF07933.9 OAJ22275.1 - 5.4e-51 172.3 0.0 6.3e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Ribonuclease_T2 PF00445.13 OAJ22346.1 - 2.9e-31 108.5 0.0 3.7e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Melibiase PF02065.13 OAJ22346.1 - 0.067 11.8 0.0 0.78 8.3 0.0 2.0 2 0 0 2 2 2 0 Melibiase AIRS PF00586.19 OAJ22346.1 - 0.09 13.0 0.0 0.27 11.4 0.0 1.8 1 1 0 1 1 1 0 AIR synthase related protein, N-terminal domain Cyt-b5 PF00173.23 OAJ22347.1 - 1.1e-20 73.2 0.0 2.2e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 OAJ22347.1 - 0.011 16.1 0.6 0.11 12.9 0.0 2.3 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily SHMT PF00464.14 OAJ22348.1 - 2.4e-167 556.3 0.0 2.8e-167 556.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 OAJ22348.1 - 0.0064 15.6 0.0 0.009 15.1 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 OAJ22348.1 - 0.019 13.9 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_5 PF00266.14 OAJ22348.1 - 0.08 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V TspO_MBR PF03073.10 OAJ22349.1 - 3.2e-41 140.2 11.1 3.7e-41 140.0 7.7 1.0 1 0 0 1 1 1 1 TspO/MBR family DUF1771 PF08590.5 OAJ22349.1 - 0.073 13.0 1.9 0.13 12.2 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) PDH PF02153.12 OAJ22350.1 - 4.8e-12 45.3 0.0 6.7e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 OAJ22350.1 - 1.4e-07 31.8 0.0 4.5e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 OAJ22350.1 - 7.4e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 OAJ22350.1 - 0.00044 19.4 0.0 0.00075 18.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 OAJ22350.1 - 0.0012 18.9 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 OAJ22350.1 - 0.006 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 ThiF family ApbA PF02558.11 OAJ22350.1 - 0.0092 15.4 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 OAJ22350.1 - 0.017 14.8 0.0 0.04 13.5 0.0 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rad21_Rec8_N PF04825.8 OAJ22351.1 - 1.2e-41 141.1 0.0 2.1e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 OAJ22351.1 - 9.1e-15 53.5 0.1 2.5e-14 52.2 0.1 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 OAJ22351.1 - 4.6e-05 23.1 0.0 0.00061 19.4 0.0 2.2 2 0 0 2 2 2 1 ScpA/B protein FliG_C PF01706.11 OAJ22351.1 - 0.1 12.5 0.6 0.23 11.4 0.4 1.5 1 0 0 1 1 1 0 FliG C-terminal domain A_deaminase PF00962.17 OAJ22352.1 - 2.8e-46 157.9 0.0 7.1e-46 156.6 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 OAJ22352.1 - 2.8e-06 27.2 0.0 5.6e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal NOB1_Zn_bind PF08772.6 OAJ22354.1 - 1.3e-27 95.3 2.4 3.5e-27 94.0 1.7 1.7 1 1 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.1 OAJ22354.1 - 1.6 8.0 4.9 3.6 6.9 3.4 1.6 1 0 0 1 1 1 0 zinc-ribbon domain GTP_EFTU PF00009.22 OAJ22355.1 - 7.3e-49 165.7 0.0 1.2e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 OAJ22355.1 - 1.2e-34 118.4 0.1 2.4e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 OAJ22355.1 - 3.1e-13 49.3 0.0 7.6e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 OAJ22355.1 - 1.3e-05 25.1 0.2 2.8e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 OAJ22355.1 - 0.00012 21.8 0.0 0.0003 20.5 0.0 1.7 1 1 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 OAJ22355.1 - 0.0031 16.7 0.0 0.0067 15.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 OAJ22355.1 - 0.033 14.6 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Dimer_Tnp_hAT PF05699.9 OAJ22356.1 - 1.6e-15 56.5 0.1 4.4e-15 55.0 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.20 OAJ22357.1 - 1.5e-05 24.2 0.0 2.6e-05 23.4 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain TPR_12 PF13424.1 OAJ22358.1 - 0.07 13.0 0.0 0.4 10.6 0.0 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat FdhE PF04216.7 OAJ22359.1 - 0.067 12.8 0.3 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF605 PF04652.11 OAJ22359.1 - 0.12 11.7 6.5 0.13 11.6 4.5 1.1 1 0 0 1 1 1 0 Vta1 like MIP-T3 PF10243.4 OAJ22359.1 - 0.16 10.3 3.8 0.2 10.1 2.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 adh_short PF00106.20 OAJ22360.1 - 9.2e-11 41.9 0.1 1.1e-10 41.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ22360.1 - 2.4e-06 27.4 0.2 3.4e-06 27.0 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ22360.1 - 0.079 12.6 0.1 0.092 12.4 0.1 1.2 1 0 0 1 1 1 0 KR domain ATP-synt_DE_N PF02823.11 OAJ22361.1 - 0.00027 20.6 0.0 0.00041 20.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Kinesin PF00225.18 OAJ22436.1 - 9.1e-106 353.3 0.1 2.3e-105 352.0 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain Plasmodium_Vir PF05795.6 OAJ22437.1 - 0.095 11.8 0.1 0.81 8.8 0.0 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Nucleoplasmin PF03066.10 OAJ22437.1 - 0.65 9.5 3.6 0.65 9.5 0.8 2.1 2 0 0 2 2 2 0 Nucleoplasmin SVM_signal PF12113.3 OAJ22437.1 - 1.6 8.6 2.9 2.6 7.9 2.0 1.3 1 0 0 1 1 1 0 SVM protein signal sequence Gcd10p PF04189.8 OAJ22438.1 - 4.9e-69 232.7 0.0 7.3e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family RNase_H2_suC PF08615.6 OAJ22438.1 - 0.067 13.0 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Ribosomal_S10 PF00338.17 OAJ22439.1 - 2.3e-31 107.4 0.2 2.8e-31 107.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Aminotran_3 PF00202.16 OAJ22440.1 - 1.9e-34 119.0 0.0 1.5e-15 56.8 0.0 3.2 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.1 OAJ22440.1 - 2.6e-26 92.4 0.0 6.1e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain GST_N_3 PF13417.1 OAJ22441.1 - 1e-15 57.6 0.0 1.2e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAJ22441.1 - 5.1e-13 48.9 0.0 6.2e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ22441.1 - 4.6e-11 42.5 0.0 5.8e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 OAJ22441.1 - 0.038 13.9 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Glutaredoxin Shisa PF13908.1 OAJ22442.1 - 4.2 7.4 6.6 7.5 6.6 4.6 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Clr2 PF10383.4 OAJ22444.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 ABC_tran PF00005.22 OAJ22445.1 - 9.5e-45 152.2 0.0 1e-23 84.1 0.0 3.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 OAJ22445.1 - 5.6e-16 59.3 2.8 0.0001 22.4 0.0 4.3 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 OAJ22445.1 - 2.4e-10 40.0 0.1 0.017 14.3 0.0 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAJ22445.1 - 3e-08 34.2 0.0 0.0022 18.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAJ22445.1 - 9e-07 28.3 0.3 0.052 13.0 0.1 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain HEAT PF02985.17 OAJ22445.1 - 2.5e-06 27.0 2.2 1 9.5 0.0 5.8 5 0 0 5 5 5 1 HEAT repeat Chromo PF00385.19 OAJ22445.1 - 7.2e-06 25.5 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Miro PF08477.8 OAJ22445.1 - 9.6e-06 26.0 0.2 0.071 13.6 0.0 3.5 3 0 0 3 3 3 1 Miro-like protein MMR_HSR1 PF01926.18 OAJ22445.1 - 1e-05 25.4 0.0 0.022 14.6 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_15 PF13175.1 OAJ22445.1 - 2.3e-05 23.6 0.0 1.1 8.2 0.0 3.3 2 1 0 3 3 3 2 AAA ATPase domain HEAT_2 PF13646.1 OAJ22445.1 - 2.7e-05 24.3 13.2 0.00047 20.3 0.8 4.7 2 1 1 4 4 3 1 HEAT repeats AAA_22 PF13401.1 OAJ22445.1 - 0.00016 21.8 0.1 2.6 8.1 0.0 4.0 4 1 0 4 4 3 2 AAA domain HEAT_EZ PF13513.1 OAJ22445.1 - 0.00023 21.5 10.3 0.2 12.1 0.1 6.1 4 2 3 7 7 6 1 HEAT-like repeat AAA_10 PF12846.2 OAJ22445.1 - 0.00044 19.7 2.2 0.95 8.8 0.0 4.2 4 1 0 4 4 4 1 AAA-like domain AAA_25 PF13481.1 OAJ22445.1 - 0.00053 19.4 0.1 6.3 6.1 0.0 3.9 4 0 0 4 4 4 0 AAA domain NACHT PF05729.7 OAJ22445.1 - 0.00079 19.1 0.0 1 9.0 0.0 2.8 2 0 0 2 2 2 2 NACHT domain DUF258 PF03193.11 OAJ22445.1 - 0.00088 18.4 0.1 0.056 12.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 OAJ22445.1 - 0.00099 19.1 8.0 0.021 14.7 0.0 4.4 3 1 0 4 4 4 1 AAA ATPase domain AAA_28 PF13521.1 OAJ22445.1 - 0.0011 19.0 0.1 6.7 6.6 0.0 3.7 3 0 0 3 3 3 0 AAA domain ArgK PF03308.11 OAJ22445.1 - 0.0013 17.5 0.2 0.17 10.6 0.0 2.5 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 OAJ22445.1 - 0.0025 18.6 0.0 0.59 10.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAJ22445.1 - 0.0033 17.3 0.0 0.55 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 OAJ22445.1 - 0.0037 17.1 0.0 0.68 9.8 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 OAJ22445.1 - 0.0042 16.6 0.3 1.1 8.8 0.0 3.1 4 0 0 4 4 2 1 AAA domain MobB PF03205.9 OAJ22445.1 - 0.0047 16.6 0.4 2 8.0 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Adaptin_N PF01602.15 OAJ22445.1 - 0.0049 15.2 0.6 0.14 10.4 0.3 2.5 1 1 1 2 2 2 2 Adaptin N terminal region DUF87 PF01935.12 OAJ22445.1 - 0.017 14.9 0.7 7.5 6.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 GTP_EFTU PF00009.22 OAJ22445.1 - 0.022 14.2 0.3 0.74 9.2 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Zeta_toxin PF06414.7 OAJ22445.1 - 0.037 13.1 0.3 12 4.9 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin KAP_NTPase PF07693.9 OAJ22445.1 - 0.077 11.9 0.1 8.9 5.1 0.0 2.9 3 0 0 3 3 3 0 KAP family P-loop domain Dynamin_N PF00350.18 OAJ22445.1 - 0.12 12.1 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.17 OAJ22445.1 - 0.16 12.1 0.0 6.2 7.0 0.0 3.0 3 0 0 3 3 3 0 RNA helicase PduV-EutP PF10662.4 OAJ22445.1 - 0.17 11.3 1.1 7.6 6.0 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MFS_1 PF07690.11 OAJ22446.1 - 4.2e-33 114.5 27.6 4.2e-33 114.5 19.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily FCH PF00611.18 OAJ22447.1 - 3.4e-16 59.1 0.0 3.4e-16 59.1 0.0 2.7 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain TPR_MLP1_2 PF07926.7 OAJ22447.1 - 0.029 14.0 10.6 0.79 9.4 4.5 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein SdrG_C_C PF10425.4 OAJ22447.1 - 0.033 14.1 0.4 0.056 13.4 0.3 1.3 1 0 0 1 1 1 0 C-terminus of bacterial fibrinogen-binding adhesin SUI1 PF01253.17 OAJ22448.1 - 4.3e-11 42.4 0.0 8.2e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 SPATIAL PF15256.1 OAJ22448.1 - 0.062 13.3 0.2 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 SPATIAL GA PF01468.12 OAJ22448.1 - 2.2 8.5 7.8 0.15 12.2 1.1 2.2 3 0 0 3 3 3 0 GA module BRO1 PF03097.13 OAJ22449.1 - 6.1e-94 314.8 0.5 1.1e-93 313.9 0.0 1.6 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 OAJ22449.1 - 4.2e-63 213.0 14.1 1.8e-62 211.0 9.8 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV PI-PLC-X PF00388.14 OAJ22450.1 - 0.032 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain GCV_H PF01597.14 OAJ22517.1 - 1.5e-40 137.6 1.0 1.8e-40 137.4 0.7 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 OAJ22517.1 - 0.0012 18.4 0.6 0.0025 17.4 0.3 1.6 2 0 0 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.1 OAJ22517.1 - 0.009 15.7 0.1 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain TfoX_C PF04994.8 OAJ22517.1 - 0.12 12.2 0.0 0.76 9.7 0.0 2.1 2 1 0 2 2 2 0 TfoX C-terminal domain tRNA_m1G_MT PF01746.16 OAJ22518.1 - 2.1e-20 73.1 0.1 9.7e-16 57.8 0.1 3.2 2 1 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase FA_hydroxylase PF04116.8 OAJ22519.1 - 2.6e-12 47.1 11.0 2.6e-12 47.1 7.6 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily zf-CSL PF05207.8 OAJ22520.1 - 1.1e-23 82.5 1.0 1.1e-23 82.5 0.7 1.4 2 0 0 2 2 2 1 CSL zinc finger zinc_ribbon_5 PF13719.1 OAJ22520.1 - 0.0014 18.1 0.8 0.0022 17.5 0.6 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 OAJ22520.1 - 0.0045 16.6 1.1 0.0072 15.9 0.8 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-RING_4 PF14570.1 OAJ22520.1 - 0.038 13.5 0.5 0.072 12.6 0.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.5 OAJ22520.1 - 0.044 13.7 0.6 0.087 12.7 0.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Sad1_UNC PF07738.8 OAJ22521.1 - 1.7e-22 79.6 0.0 1.2e-12 47.7 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal GP40 PF11025.3 OAJ22522.1 - 0.073 12.6 0.8 0.17 11.4 0.5 1.5 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium DUF1768 PF08719.6 OAJ22523.1 - 2.2e-29 102.2 0.0 2.8e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.6 OAJ22523.1 - 8.6e-05 22.0 0.0 0.00029 20.3 0.0 1.8 1 1 0 1 1 1 1 Bacteriophage protein GP30.3 zf-Tim10_DDP PF02953.10 OAJ22524.1 - 3.3e-18 64.7 4.5 3.3e-18 64.7 3.1 1.5 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Ssu72 PF04722.8 OAJ22524.1 - 0.051 12.8 0.1 0.058 12.7 0.1 1.1 1 0 0 1 1 1 0 Ssu72-like protein Mmp37 PF09139.6 OAJ22524.1 - 0.079 11.9 0.1 0.086 11.8 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Syja_N PF02383.13 OAJ22525.1 - 5e-90 301.5 0.0 6.1e-90 301.2 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Abhydrolase_5 PF12695.2 OAJ22526.1 - 3e-24 85.4 0.0 5e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ22526.1 - 3.7e-16 59.6 1.8 2.4e-14 53.7 1.2 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ22526.1 - 3.3e-08 33.3 0.0 0.0046 16.5 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 OAJ22526.1 - 6.3e-07 28.1 0.0 0.0021 16.5 0.0 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 OAJ22526.1 - 0.00035 20.0 0.0 0.0024 17.3 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 OAJ22526.1 - 0.0016 18.2 0.1 0.018 14.7 0.0 2.4 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 OAJ22526.1 - 0.0034 16.6 0.0 0.046 12.9 0.0 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 OAJ22526.1 - 0.013 14.8 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.15 OAJ22526.1 - 0.046 13.1 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Ub-Mut7C PF14451.1 OAJ22526.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 Mut7-C ubiquitin Abhydrolase_2 PF02230.11 OAJ22526.1 - 0.17 11.3 0.0 17 4.7 0.0 2.4 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase YL1 PF05764.8 OAJ22527.1 - 0.26 10.8 22.6 0.01 15.4 5.9 3.2 3 0 0 3 3 3 0 YL1 nuclear protein DEAD PF00270.24 OAJ22530.1 - 6.2e-11 42.0 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Spb1_C PF07780.7 OAJ22531.1 - 8.6e-67 224.7 29.7 8.6e-67 224.7 20.6 3.5 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 OAJ22531.1 - 5.6e-53 179.6 0.0 1.4e-52 178.2 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 OAJ22531.1 - 1.1e-41 141.9 9.9 1.1e-41 141.9 6.9 5.3 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) Rtf2 PF04641.7 OAJ22532.1 - 1.9e-54 184.6 0.0 5.4e-54 183.1 0.0 1.8 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 OAJ22532.1 - 0.069 12.6 0.0 1.8 8.1 0.0 2.7 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit Zn_clus PF00172.13 OAJ22602.1 - 0.046 13.6 7.8 0.12 12.3 5.1 1.9 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MAT1 PF06391.8 OAJ22604.1 - 1.5e-36 125.9 5.1 2.2e-36 125.3 3.5 1.3 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 OAJ22604.1 - 0.00015 21.2 8.1 0.00034 20.1 5.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ22604.1 - 0.00073 19.2 7.4 0.0021 17.7 5.2 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-ISL3 PF14690.1 OAJ22604.1 - 0.008 16.1 1.3 0.14 12.1 0.0 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C3HC4_2 PF13923.1 OAJ22604.1 - 0.014 15.4 10.2 0.048 13.6 7.2 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 OAJ22604.1 - 0.02 14.4 8.5 0.077 12.5 2.8 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 OAJ22604.1 - 0.25 11.1 10.2 0.89 9.4 7.2 1.8 1 1 1 2 2 2 0 Ring finger domain DZR PF12773.2 OAJ22604.1 - 1.9 8.3 8.8 5.4 6.9 6.1 1.7 1 1 0 1 1 1 0 Double zinc ribbon FAD_binding_3 PF01494.14 OAJ22605.1 - 2.2e-21 76.3 0.7 1.1e-10 41.1 0.0 3.4 2 2 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAJ22605.1 - 7.1e-08 31.7 0.1 2.5e-07 29.9 0.1 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ22605.1 - 5e-06 26.4 0.0 3.6e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAJ22605.1 - 4.4e-05 23.7 0.0 0.00027 21.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 OAJ22605.1 - 0.00073 19.0 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA SE PF08491.5 OAJ22605.1 - 0.00079 18.3 0.0 0.094 11.5 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase HI0933_like PF03486.9 OAJ22605.1 - 0.00093 17.7 0.0 0.0014 17.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 OAJ22605.1 - 0.0038 16.1 0.0 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 OAJ22605.1 - 0.0041 16.8 0.0 0.0074 15.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 OAJ22605.1 - 0.0064 16.3 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 OAJ22605.1 - 0.017 15.1 0.0 0.052 13.5 0.0 1.9 1 0 0 1 1 1 0 NADH(P)-binding ThiF PF00899.16 OAJ22605.1 - 0.06 13.1 0.2 0.17 11.7 0.2 1.8 1 0 0 1 1 1 0 ThiF family FAD_oxidored PF12831.2 OAJ22605.1 - 0.06 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 OAJ22605.1 - 0.063 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 OAJ22605.1 - 0.1 11.7 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PBP PF01161.15 OAJ22606.1 - 2.2e-14 53.5 0.1 3.5e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ALG3 PF05208.8 OAJ22607.1 - 6.3e-118 394.1 9.7 8.9e-118 393.7 6.7 1.2 1 0 0 1 1 1 1 ALG3 protein Drc1-Sld2 PF11719.3 OAJ22608.1 - 3.1e-10 39.7 6.3 3.1e-10 39.7 4.4 5.3 1 1 2 3 3 3 1 DNA replication and checkpoint protein Clathrin PF00637.15 OAJ22609.1 - 5.8e-15 55.1 0.4 4.4e-06 26.3 0.0 3.5 3 0 0 3 3 3 3 Region in Clathrin and VPS VPS11_C PF12451.3 OAJ22609.1 - 3.6e-08 33.1 0.4 3.6e-08 33.1 0.3 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 OAJ22609.1 - 0.012 15.4 6.6 0.021 14.6 4.6 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 OAJ22609.1 - 0.17 11.6 6.5 0.29 10.9 4.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAJ22609.1 - 0.44 10.6 6.1 0.79 9.8 4.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 OAJ22609.1 - 0.78 9.5 7.1 1.4 8.6 4.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 OAJ22609.1 - 1.7 8.4 5.6 3.2 7.5 3.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.20 OAJ22609.1 - 6 6.6 6.6 11 5.8 4.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_4 PF13717.1 OAJ22609.1 - 6.6 6.5 4.0 2.5 7.8 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain 2-oxoacid_dh PF00198.18 OAJ22610.1 - 4.2e-56 189.8 0.0 7.6e-55 185.6 0.0 2.4 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 OAJ22610.1 - 3.7e-19 68.1 0.1 5.7e-19 67.5 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 OAJ22610.1 - 3.9e-15 55.1 0.3 9.8e-15 53.9 0.2 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 OAJ22610.1 - 0.01 15.4 0.0 0.084 12.5 0.0 2.2 1 1 1 2 2 2 0 Biotin-lipoyl like HlyD_2 PF12700.2 OAJ22610.1 - 0.073 12.2 0.0 0.88 8.6 0.0 2.0 1 1 1 2 2 2 0 HlyD family secretion protein PYNP_C PF07831.8 OAJ22610.1 - 0.078 12.4 0.0 18 4.9 0.0 2.5 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain GCV_H PF01597.14 OAJ22610.1 - 0.2 11.3 0.1 0.36 10.5 0.1 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein Nop25 PF09805.4 OAJ22611.1 - 1.6e-21 76.8 8.3 1.6e-21 76.8 5.7 2.5 3 0 0 3 3 3 1 Nucleolar protein 12 (25kDa) Ebola_NP PF05505.7 OAJ22611.1 - 0.37 8.7 8.7 0.45 8.5 6.1 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein RTA1 PF04479.8 OAJ22613.1 - 4.5e-35 121.1 6.4 5.9e-35 120.7 4.4 1.2 1 0 0 1 1 1 1 RTA1 like protein Claudin_2 PF13903.1 OAJ22613.1 - 1.7 8.3 9.1 0.14 11.8 0.6 2.7 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Phage_integrase PF00589.17 OAJ22615.1 - 3.1e-06 26.9 0.0 9.6e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 OAJ22616.1 - 1.9e-26 92.7 0.0 3e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ22616.1 - 6.2e-12 45.1 0.0 1.1e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ22616.1 - 9.7e-08 32.2 0.0 1.7e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.19 OAJ22617.1 - 1.8e-13 50.9 0.0 2.8e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 RNase H Mmp37 PF09139.6 OAJ22688.1 - 5.2e-99 331.3 0.0 9.9e-99 330.4 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial matrix Mmp37 HlyIII PF03006.15 OAJ22691.1 - 2.3e-49 167.8 19.3 3.5e-49 167.2 13.4 1.3 1 0 0 1 1 1 1 Haemolysin-III related UPF0060 PF02694.10 OAJ22691.1 - 0.072 13.1 3.4 0.066 13.2 0.6 2.3 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Cation_ATPase_C PF00689.16 OAJ22691.1 - 0.11 12.0 6.3 0.16 11.5 0.2 2.9 1 1 2 3 3 3 0 Cation transporting ATPase, C-terminus Form-deh_trans PF09163.6 OAJ22691.1 - 2 7.9 9.5 0.99 8.9 0.1 3.2 3 0 0 3 3 3 0 Formate dehydrogenase N, transmembrane E_Pc_C PF06752.7 OAJ22692.1 - 0.27 10.6 4.1 0.32 10.4 2.8 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus SSP160 PF06933.6 OAJ22692.1 - 1.1 7.2 4.9 1.1 7.1 3.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FAD_binding_4 PF01565.18 OAJ22693.1 - 3.7e-15 55.6 0.3 6.6e-10 38.5 0.0 4.1 5 0 0 5 5 5 2 FAD binding domain BBE PF08031.7 OAJ22693.1 - 3.7e-07 29.9 0.0 8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Med3 PF11593.3 OAJ22693.1 - 0.58 9.3 11.4 1.1 8.3 7.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SMC_N PF02463.14 OAJ22696.1 - 6e-68 228.3 1.3 8.9e-68 227.8 0.9 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 OAJ22696.1 - 5.6e-31 107.0 0.2 2.1e-30 105.1 0.0 2.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 OAJ22696.1 - 7e-14 52.4 8.4 2.4e-06 27.7 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_23 PF13476.1 OAJ22696.1 - 3.7e-10 40.4 43.6 3.7e-10 40.4 30.2 6.9 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 OAJ22696.1 - 0.0029 17.0 0.0 0.0075 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 OAJ22696.1 - 0.17 12.1 19.5 4.1 7.6 3.4 5.2 3 2 0 3 3 3 0 ABC transporter FtsK_SpoIIIE PF01580.13 OAJ22696.1 - 0.37 10.2 0.0 0.37 10.2 0.0 4.5 6 0 0 6 6 6 0 FtsK/SpoIIIE family HMA PF00403.21 OAJ22696.1 - 0.54 10.4 3.7 0.3 11.2 0.1 2.6 3 0 0 3 3 3 0 Heavy-metal-associated domain SNF2_N PF00176.18 OAJ22698.1 - 1.3e-59 201.4 0.0 3.7e-30 104.7 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ22698.1 - 6.7e-10 38.6 0.0 2e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 OAJ22698.1 - 3.8e-09 36.4 6.1 7.4e-09 35.4 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ22698.1 - 3.9e-09 36.0 5.3 7.6e-09 35.0 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ22698.1 - 1.8e-08 34.0 4.7 3.4e-08 33.1 3.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 OAJ22698.1 - 2e-06 27.5 8.0 4.8e-06 26.3 5.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 OAJ22698.1 - 2.9e-06 26.8 2.3 5.8e-06 25.8 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ22698.1 - 2e-05 24.2 3.1 4.2e-05 23.1 2.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ22698.1 - 0.00015 21.4 4.1 0.00035 20.2 2.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 OAJ22698.1 - 0.012 15.7 1.9 0.036 14.1 1.3 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger DUF2019 PF09450.5 OAJ22698.1 - 0.039 13.8 0.2 0.099 12.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) zf-RING_6 PF14835.1 OAJ22698.1 - 0.056 13.2 1.9 0.12 12.2 1.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FGGY_C PF02782.11 OAJ22699.1 - 1.7e-43 148.5 0.1 2.6e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 OAJ22699.1 - 7.3e-24 84.4 0.0 6.3e-23 81.3 0.0 2.4 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 OAJ22699.1 - 5.3e-06 25.9 0.3 2.3e-05 23.8 0.1 1.9 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.16 OAJ22699.1 - 0.0093 15.3 0.0 0.032 13.5 0.0 1.8 2 0 0 2 2 2 1 Hexokinase DUF4445 PF14574.1 OAJ22699.1 - 0.16 10.1 0.1 4.3 5.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4445) Response_reg PF00072.19 OAJ22789.1 - 1.7e-23 82.7 0.0 3.9e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 OAJ22789.1 - 3.8e-19 68.4 0.0 6.4e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 OAJ22789.1 - 2.5e-09 36.9 2.6 1.1e-08 34.8 0.1 2.9 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain GxGYxYP PF14323.1 OAJ22789.1 - 0.31 9.6 0.0 0.48 9.0 0.0 1.1 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function Phosducin PF02114.11 OAJ22790.1 - 0.019 13.7 0.8 3.6 6.2 0.4 2.3 2 0 0 2 2 2 0 Phosducin PBP1_TM PF14812.1 OAJ22790.1 - 0.41 10.9 16.6 0.4 11.0 7.7 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pap_E4 PF02711.9 OAJ22790.1 - 0.71 10.7 7.3 0.23 12.2 2.1 2.3 2 0 0 2 2 2 0 E4 protein FAM176 PF14851.1 OAJ22790.1 - 3.5 7.2 5.1 2.9 7.5 1.1 2.2 2 0 0 2 2 2 0 FAM176 family CAP-ZIP_m PF15255.1 OAJ22790.1 - 6.7 6.6 10.5 0.36 10.7 0.4 2.5 2 1 0 2 2 2 0 WASH complex subunit CAP-Z interacting, central region FLO_LFY PF01698.11 OAJ22792.1 - 3.2 6.4 7.0 5 5.8 4.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein FKBP_C PF00254.23 OAJ22793.1 - 1.2e-32 111.8 0.0 1.3e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FDC-SP PF15215.1 OAJ22794.1 - 0.15 12.3 2.4 0.26 11.5 1.7 1.3 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide FKBP_C PF00254.23 OAJ22795.1 - 6.2e-30 103.0 0.0 7e-30 102.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Metallophos PF00149.23 OAJ22796.1 - 1.5e-10 40.8 0.0 2.5e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ferric_reduct PF01794.14 OAJ22797.1 - 4e-21 75.3 10.8 4e-21 75.3 7.5 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 OAJ22797.1 - 1.8e-17 63.6 0.0 2.6e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 OAJ22797.1 - 1.7e-09 37.4 0.0 5e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 OAJ22797.1 - 0.037 14.6 0.0 0.78 10.3 0.0 2.3 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain Ferritin_2 PF13668.1 OAJ22799.1 - 8.6e-11 41.9 0.0 1.1e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain TFIIA PF03153.8 OAJ22799.1 - 0.0066 16.3 4.7 0.0068 16.3 3.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SNARE_assoc PF09335.6 OAJ22804.1 - 7.6e-12 45.5 4.7 7.6e-12 45.5 3.3 2.7 3 0 0 3 3 3 1 SNARE associated Golgi protein Nop14 PF04147.7 OAJ22804.1 - 2.1 6.1 11.3 3.9 5.2 7.8 1.3 1 0 0 1 1 1 0 Nop14-like family HAD PF12710.2 OAJ22805.1 - 1.5e-08 35.0 0.0 2.9e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2975 PF11188.3 OAJ22897.1 - 6.8 6.4 8.6 1.2 8.8 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) DUF1768 PF08719.6 OAJ22898.1 - 9.6e-12 44.9 1.4 1.5e-11 44.2 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) UPF0167 PF03691.9 OAJ22898.1 - 0.03 13.7 0.3 0.048 13.0 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) UCH PF00443.24 OAJ22899.1 - 2.9e-41 141.3 0.0 3.7e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ22899.1 - 6.5e-12 45.4 0.0 3.8e-05 23.2 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DNA_pol_A PF00476.15 OAJ22900.1 - 9e-89 297.7 0.0 3e-88 296.0 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase family A PARP PF00644.15 OAJ22901.1 - 0.023 14.0 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.6 OAJ22902.1 - 9.4e-24 83.9 0.0 1.4e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1769 PF08588.5 OAJ22904.1 - 5e-21 74.3 0.1 1.2e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Glyco_hydro_3 PF00933.16 OAJ22905.1 - 2.6e-84 282.7 0.0 4.1e-84 282.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 OAJ22905.1 - 7.8e-57 192.4 2.5 1.5e-56 191.4 0.4 2.3 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 OAJ22905.1 - 9.3e-19 67.1 0.0 1.9e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain P34-Arc PF04045.9 OAJ22906.1 - 1.3e-104 348.7 0.1 2.6e-104 347.7 0.0 1.5 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc XRN_N PF03159.13 OAJ22906.1 - 1.8e-97 325.3 0.0 3.3e-97 324.5 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus adh_short PF00106.20 OAJ22907.1 - 4e-23 82.1 0.0 6.1e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ22907.1 - 2.8e-06 27.3 0.0 4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ22907.1 - 5.9e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAJ22907.1 - 0.0046 16.9 0.0 0.0078 16.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAJ22907.1 - 0.05 13.0 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4078 PF13300.1 OAJ22908.1 - 2e-16 59.8 1.3 2e-16 59.8 0.9 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) Exo_endo_phos PF03372.18 OAJ22909.1 - 3.2e-10 40.3 0.7 1.3e-09 38.3 0.1 2.3 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Cys_Met_Meta_PP PF01053.15 OAJ22910.1 - 4.2e-22 77.9 0.0 2.3e-15 55.7 0.0 2.2 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 OAJ22910.1 - 0.15 11.0 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II An_peroxidase PF03098.10 OAJ22916.1 - 9e-77 258.6 0.0 8.5e-57 192.7 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 OAJ22916.1 - 1.2e-12 47.1 0.0 2e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF2235 PF09994.4 OAJ22917.1 - 1.1e-77 261.1 0.0 1.7e-77 260.5 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 OAJ22917.1 - 0.0043 16.8 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.6 OAJ22917.1 - 0.038 13.7 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2400 PF09674.5 OAJ22917.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Cutinase PF01083.17 OAJ22918.1 - 9.6e-24 84.0 0.0 1.2e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ22918.1 - 8.5e-05 22.2 0.0 0.00017 21.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 OAJ22918.1 - 0.0021 17.5 0.1 0.0039 16.7 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase Abhydrolase_6 PF12697.2 OAJ22918.1 - 0.0055 16.6 0.0 0.0059 16.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 OAJ22918.1 - 0.04 13.3 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_9 PF10081.4 OAJ22918.1 - 0.1 11.2 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Cutinase PF01083.17 OAJ22919.1 - 3.5e-28 98.5 0.0 8.1e-28 97.3 0.0 1.5 1 1 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ22919.1 - 0.0008 19.0 0.0 0.00099 18.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 OAJ22919.1 - 0.0024 17.3 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PE-PPE PF08237.6 OAJ22919.1 - 0.028 13.8 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_9 PF10081.4 OAJ22919.1 - 0.028 13.1 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family DUF676 PF05057.9 OAJ22919.1 - 0.058 12.6 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.7 OAJ22919.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase Thioesterase PF00975.15 OAJ22919.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain BAR_3_WASP_bdg PF10456.4 OAJ22921.1 - 2.4e-08 33.5 0.6 1.3e-07 31.1 0.4 1.8 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PXA PF02194.10 OAJ22921.1 - 0.16 11.4 1.4 0.25 10.9 0.9 1.2 1 0 0 1 1 1 0 PXA domain PX PF00787.19 OAJ22922.1 - 4.7e-17 61.8 0.1 3.2e-16 59.1 0.0 2.3 2 0 0 2 2 2 1 PX domain SH3_1 PF00018.23 OAJ22922.1 - 2.1e-05 23.8 0.0 4.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Zn_clus PF00172.13 OAJ22923.1 - 1.4e-05 24.8 10.2 2.2e-05 24.2 7.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3684 PF12449.3 OAJ22924.1 - 6.2e-284 944.6 0.0 9.2e-266 884.4 0.0 4.4 2 2 0 2 2 2 2 Protein of unknown function (DUF3684) DUF106 PF01956.11 OAJ22925.1 - 1.9e-57 193.4 0.8 2.3e-57 193.1 0.6 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 Cwf_Cwc_15 PF04889.7 OAJ22927.1 - 9.8e-67 225.2 16.2 1.1e-66 224.9 11.2 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3245 PF11595.3 OAJ22927.1 - 0.031 14.5 2.4 0.031 14.5 1.7 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3245) Nop53 PF07767.6 OAJ22927.1 - 0.3 10.0 20.1 0.057 12.4 8.4 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) CENP-T PF15511.1 OAJ22927.1 - 2.5 7.2 24.8 3.9 6.6 17.2 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SGT1 PF07093.6 OAJ22927.1 - 3 6.1 18.6 3.8 5.7 12.9 1.1 1 0 0 1 1 1 0 SGT1 protein WD40 PF00400.27 OAJ22928.1 - 6.6e-16 57.5 0.8 2.1e-05 24.1 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat MULE PF10551.4 OAJ22929.1 - 3.7e-12 46.2 0.1 1.4e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 OAJ22929.1 - 2.1e-08 33.1 2.5 1e-07 30.9 0.1 2.2 2 0 0 2 2 2 1 Transposase, Mutator family FAR1 PF03101.10 OAJ22929.1 - 0.014 15.9 1.2 0.029 14.8 0.8 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain p450 PF00067.17 OAJ22930.1 - 2.8e-63 214.0 0.0 6.6e-63 212.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 OAJ22931.1 - 4e-63 213.5 0.0 8.4e-63 212.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 zf-UBR PF02207.15 OAJ22937.1 - 0.098 12.3 7.9 0.19 11.4 5.3 1.6 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Stress-antifung PF01657.12 OAJ22937.1 - 0.17 12.1 5.7 0.22 11.8 4.0 1.2 1 0 0 1 1 1 0 Salt stress response/antifungal Dickkopf_N PF04706.7 OAJ22937.1 - 0.45 10.7 5.9 0.67 10.1 4.1 1.3 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region TRAPPC10 PF12584.3 OAJ22938.1 - 8.6e-22 77.2 0.0 1.8e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gpi1 PF05024.10 OAJ22939.1 - 3.7e-41 140.8 0.5 5.9e-41 140.2 0.3 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) FMO-like PF00743.14 OAJ22940.1 - 1.5e-33 115.7 0.0 4.9e-19 67.9 0.0 3.1 2 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 OAJ22940.1 - 2.3e-13 50.6 0.0 2.6e-12 47.2 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ22940.1 - 4.1e-06 25.9 0.3 0.0018 17.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAJ22940.1 - 5.4e-06 26.2 0.0 0.00024 20.9 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAJ22940.1 - 4.9e-05 23.3 0.0 0.13 12.1 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAJ22940.1 - 0.00047 20.1 0.1 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 OAJ22940.1 - 0.016 14.3 0.0 0.3 10.1 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Malic_M PF03949.10 OAJ22940.1 - 0.17 11.3 0.1 0.69 9.4 0.0 1.9 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain DUF1279 PF06916.8 OAJ22941.1 - 0.028 14.7 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) Aldo_ket_red PF00248.16 OAJ22942.1 - 2.8e-15 55.9 0.0 2.2e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family ELFV_dehydrog PF00208.16 OAJ22943.1 - 5.1e-46 157.2 0.0 8e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 OAJ22943.1 - 2.3e-20 71.7 0.0 1.6e-14 52.4 0.0 2.3 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 OAJ22943.1 - 0.0015 18.0 0.0 0.0038 16.8 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF443 PF04276.7 OAJ22944.1 - 0.19 11.1 8.2 0.54 9.6 1.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF443) Chromate_transp PF02417.10 OAJ22944.1 - 0.86 9.1 19.5 0.027 14.0 3.8 2.7 2 1 0 2 2 2 0 Chromate transporter DNA_ligase_OB_2 PF14743.1 OAJ22945.1 - 8.7e-29 98.9 0.8 3.3e-28 97.1 0.2 2.1 2 0 0 2 2 2 1 DNA ligase OB-like domain DNA_ligase_A_C PF04679.10 OAJ22945.1 - 0.047 14.0 0.2 9.1 6.7 0.0 3.2 2 1 1 3 3 3 0 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 OAJ22946.1 - 6.3e-29 99.4 0.3 1.3e-28 98.4 0.2 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.16 OAJ22946.1 - 8.5e-12 44.8 0.0 1.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain SWIM PF04434.12 OAJ22946.1 - 0.0063 15.9 0.5 0.012 15.1 0.4 1.4 1 0 0 1 1 1 1 SWIM zinc finger Peroxidase_2 PF01328.12 OAJ22947.1 - 1.1e-15 57.1 0.4 2.7e-15 55.8 0.2 1.5 1 1 0 1 1 1 1 Peroxidase, family 2 Transp_cyt_pur PF02133.10 OAJ22948.1 - 6.5e-129 430.3 42.5 1.7e-121 405.8 23.4 2.0 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Methyltransf_11 PF08241.7 OAJ22949.1 - 3.9e-20 72.1 0.0 3.4e-09 37.0 0.0 3.5 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ22949.1 - 5.8e-14 52.6 0.0 6.9e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ22949.1 - 2.2e-12 47.2 0.0 0.00028 21.2 0.0 4.5 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ22949.1 - 4.6e-11 42.9 0.0 0.00016 21.9 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ22949.1 - 3e-10 40.1 0.2 0.0003 20.7 0.0 3.2 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ22949.1 - 8.1e-09 35.3 0.0 0.0017 18.0 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ22949.1 - 5.1e-06 26.1 0.0 0.32 10.5 0.0 4.1 3 1 0 3 3 3 1 Methyltransferase domain Neuro_bHLH PF12533.3 OAJ22949.1 - 0.059 14.1 0.0 8.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Neuronal helix-loop-helix transcription factor Meth_synt_2 PF01717.13 OAJ22950.1 - 3e-144 479.9 0.0 1.2e-136 454.9 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 OAJ22950.1 - 5.3e-121 403.6 0.0 2.8e-109 365.1 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain UQ_con PF00179.21 OAJ22951.1 - 1.1e-39 135.0 0.0 1.4e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 OAJ22951.1 - 2.4e-21 75.0 0.1 3.5e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Gly-zipper_OmpA PF13436.1 OAJ22951.1 - 0.0035 17.0 11.9 0.0053 16.4 8.3 1.2 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain DUF1421 PF07223.6 OAJ22951.1 - 0.02 14.7 0.4 0.026 14.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) UBA_2 PF08587.6 OAJ22951.1 - 0.087 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Sporozoite_P67 PF05642.6 OAJ22951.1 - 0.51 8.1 6.4 0.66 7.7 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TraV PF09676.5 OAJ22952.1 - 4.4 8.0 8.9 6.2 7.5 6.2 1.3 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) TRAUB PF08164.7 OAJ22952.1 - 5.3 7.2 12.3 17 5.5 7.7 2.2 1 1 1 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal TP53IP5 PF15331.1 OAJ22952.1 - 7.7 6.3 11.3 9.1 6.1 7.8 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Sox_N PF12444.3 OAJ22952.1 - 7.9 7.6 10.6 6.5 7.9 6.1 1.7 1 1 1 2 2 2 0 Sox developmental protein N terminal ZapA PF05164.8 OAJ22953.1 - 0.0034 17.3 1.3 0.0064 16.4 0.9 1.4 1 0 0 1 1 1 1 Cell division protein ZapA FHA PF00498.21 OAJ22954.1 - 4.2e-14 52.4 0.0 7.5e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain FF PF01846.14 OAJ22957.1 - 7.3e-20 70.6 5.9 1.6e-08 34.3 0.0 5.0 4 1 0 4 4 4 2 FF domain WW PF00397.21 OAJ22957.1 - 2.5e-12 46.4 14.1 1.3e-06 28.1 1.7 2.7 2 0 0 2 2 2 2 WW domain DDE_3 PF13358.1 OAJ22958.1 - 3.8e-28 98.0 0.0 6.3e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 OAJ22958.1 - 0.00033 20.7 0.0 0.00078 19.5 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain HTH_33 PF13592.1 OAJ22958.1 - 0.0022 17.4 0.4 0.01 15.3 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_29 PF13551.1 OAJ22958.1 - 0.0035 17.4 0.0 0.0077 16.3 0.0 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_IS630 PF01710.11 OAJ22958.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Transposase HTH_32 PF13565.1 OAJ22958.1 - 0.02 15.6 0.1 0.051 14.3 0.0 1.8 1 1 0 1 1 1 0 Homeodomain-like domain DDE_1 PF03184.14 OAJ22958.1 - 0.068 12.2 0.0 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 DDE superfamily endonuclease DUF3405 PF11885.3 OAJ22959.1 - 1.5e-136 455.5 0.4 3e-128 428.2 1.2 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF3405) Pex14_N PF04695.8 OAJ22959.1 - 1.7 8.7 4.9 1.5 8.8 0.0 2.7 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region QueF_N PF14819.1 OAJ22960.1 - 0.095 12.7 0.3 7.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term Pox_Ag35 PF03286.9 OAJ22960.1 - 0.15 11.5 2.4 0.42 10.1 1.7 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Aldo_ket_red PF00248.16 OAJ22961.1 - 1.6e-18 66.5 0.0 5.7e-14 51.6 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family AAA PF00004.24 OAJ22962.1 - 9.1e-48 161.7 0.0 2.2e-43 147.6 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 OAJ22962.1 - 3.4e-20 71.8 0.0 8.3e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_17 PF13207.1 OAJ22962.1 - 1.4e-07 32.3 0.1 0.013 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAJ22962.1 - 7.5e-07 29.3 12.1 0.014 15.3 1.4 4.9 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 OAJ22962.1 - 8.5e-07 29.1 1.9 0.098 12.7 0.1 4.3 3 2 0 3 3 2 2 AAA domain AAA_19 PF13245.1 OAJ22962.1 - 3.9e-06 26.5 0.5 0.014 15.1 0.0 3.3 3 0 0 3 3 2 2 Part of AAA domain AAA_18 PF13238.1 OAJ22962.1 - 9.3e-06 25.9 0.1 0.1 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 OAJ22962.1 - 5.4e-05 23.0 0.0 0.066 13.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 OAJ22962.1 - 5.8e-05 22.8 0.1 0.45 10.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 OAJ22962.1 - 0.00042 19.4 0.0 0.003 16.6 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 OAJ22962.1 - 0.00054 19.4 0.3 0.93 8.8 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 OAJ22962.1 - 0.00054 19.1 0.2 0.84 8.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 OAJ22962.1 - 0.00072 18.6 0.0 0.25 10.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 OAJ22962.1 - 0.00072 19.5 0.2 1.1 9.1 0.1 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 OAJ22962.1 - 0.0009 18.9 1.2 6.7 6.3 0.1 4.4 4 0 0 4 4 4 0 NACHT domain AAA_25 PF13481.1 OAJ22962.1 - 0.0015 18.0 3.3 3.4 7.0 0.1 4.1 3 1 1 4 4 4 1 AAA domain RNA_helicase PF00910.17 OAJ22962.1 - 0.0015 18.6 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 1 RNA helicase APS_kinase PF01583.15 OAJ22962.1 - 0.0041 16.7 0.0 0.081 12.5 0.0 2.7 2 1 1 3 3 3 1 Adenylylsulphate kinase AAA_14 PF13173.1 OAJ22962.1 - 0.0075 16.1 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 OAJ22962.1 - 0.0087 15.1 0.2 1 8.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_2 PF07724.9 OAJ22962.1 - 0.0094 15.8 0.0 0.06 13.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 OAJ22962.1 - 0.011 14.5 0.3 0.14 10.8 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus Viral_helicase1 PF01443.13 OAJ22962.1 - 0.014 14.9 0.1 0.052 13.0 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 OAJ22962.1 - 0.023 13.7 0.2 3.5 6.6 0.1 2.3 2 0 0 2 2 2 0 KaiC SKI PF01202.17 OAJ22962.1 - 0.037 13.9 0.2 0.76 9.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase Sigma54_activat PF00158.21 OAJ22962.1 - 0.042 13.3 0.1 2.9 7.3 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain T2SE PF00437.15 OAJ22962.1 - 0.056 12.3 0.1 0.48 9.2 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein UPF0079 PF02367.12 OAJ22962.1 - 0.075 12.6 0.2 4.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Cytidylate_kin2 PF13189.1 OAJ22962.1 - 0.079 12.8 0.8 0.57 10.0 0.0 2.7 3 0 0 3 3 3 0 Cytidylate kinase-like family NB-ARC PF00931.17 OAJ22962.1 - 0.085 11.6 0.1 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_3 PF07726.6 OAJ22962.1 - 0.17 11.5 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ribosomal_S11 PF00411.14 OAJ22963.1 - 2.6e-10 40.4 3.4 3.6e-06 27.1 0.0 2.8 3 0 0 3 3 3 2 Ribosomal protein S11 DUF605 PF04652.11 OAJ22964.1 - 0.51 9.6 39.9 0.24 10.7 23.2 2.1 2 0 0 2 2 2 0 Vta1 like MT-A70 PF05063.9 OAJ22965.1 - 8.2e-37 126.4 0.2 6.8e-26 90.8 0.0 3.2 3 0 0 3 3 3 3 MT-A70 BAF1_ABF1 PF04684.8 OAJ22965.1 - 4.3 6.0 8.2 8.5 5.0 5.7 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RNase_PH PF01138.16 OAJ22967.1 - 5e-16 59.2 0.0 1.3e-15 57.9 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 OAJ22967.1 - 0.097 12.6 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Amidohydro_1 PF01979.15 OAJ22968.1 - 1.2e-59 202.6 0.6 2e-59 201.9 0.4 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 OAJ22968.1 - 2.9e-57 192.0 0.7 8.7e-57 190.5 0.5 1.9 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.13 OAJ22968.1 - 1.8e-41 140.1 0.2 4.1e-41 139.0 0.1 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.15 OAJ22968.1 - 1.4e-35 121.0 0.0 5.8e-35 119.1 0.0 1.9 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_5 PF13594.1 OAJ22968.1 - 1.4e-05 24.8 3.6 1.4e-05 24.8 2.5 2.8 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 OAJ22968.1 - 3.5e-05 23.2 1.9 4.2e-05 22.9 0.1 1.8 1 1 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 OAJ22968.1 - 0.0037 17.3 0.0 2.8 7.8 0.0 2.8 2 0 0 2 2 2 2 Amidohydrolase Vezatin PF12632.2 OAJ22969.1 - 0.002 17.2 0.0 0.0066 15.5 0.0 1.8 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes DUF947 PF06102.7 OAJ22970.1 - 6.2e-31 107.4 9.1 6.2e-31 107.4 6.3 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF947) Sugar_tr PF00083.19 OAJ22971.1 - 1.2e-103 347.1 15.3 1.4e-103 346.9 10.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ22971.1 - 9.4e-28 96.9 23.5 9.4e-28 96.9 16.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 OAJ22971.1 - 5.9e-06 24.9 16.4 0.00079 17.9 1.6 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein DUF3180 PF11377.3 OAJ22971.1 - 0.07 12.9 0.3 0.07 12.9 0.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3180) MFS_3 PF05977.8 OAJ22971.1 - 0.095 10.7 2.3 0.15 10.1 0.2 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector Aldo_ket_red PF00248.16 OAJ22972.1 - 1.2e-09 37.3 0.0 1.3e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.14 OAJ22976.1 - 7.4e-62 209.1 0.0 1e-61 208.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ22976.1 - 2.1e-30 105.9 0.0 4.8e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAJ22976.1 - 2.5e-07 29.9 0.9 6.5e-06 25.2 0.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ22976.1 - 6.2e-06 25.3 0.1 0.00081 18.3 0.2 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 OAJ22976.1 - 2.5e-05 24.2 0.1 9.4e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAJ22976.1 - 2.5e-05 24.4 0.0 0.23 11.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAJ22976.1 - 0.00038 19.4 0.2 0.00055 18.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 OAJ22976.1 - 0.0011 17.5 0.6 0.0042 15.6 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 OAJ22976.1 - 0.0084 15.9 0.3 0.044 13.6 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase rve PF00665.21 OAJ22977.1 - 4.6e-17 62.2 0.0 1.1e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain p450 PF00067.17 OAJ22977.1 - 1.4e-12 46.9 0.0 2.4e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 rve_3 PF13683.1 OAJ22977.1 - 0.016 14.7 0.0 0.051 13.0 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain zf-CCHC PF00098.18 OAJ22978.1 - 0.00062 19.5 3.4 0.0011 18.8 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ22978.1 - 0.0037 16.7 0.3 0.0081 15.6 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 OAJ22978.1 - 0.0047 17.3 0.0 0.015 15.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ22978.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease PROL5-SMR PF15621.1 OAJ22981.1 - 0.78 10.1 13.4 1.1 9.6 9.3 1.2 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family CAF-1_p150 PF11600.3 OAJ22982.1 - 0.0011 18.4 8.6 0.0011 18.4 5.9 4.8 8 0 0 8 8 8 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal FLO_LFY PF01698.11 OAJ22982.1 - 0.69 8.6 4.9 1.9 7.2 3.4 1.7 1 0 0 1 1 1 0 Floricaula / Leafy protein NARP1 PF12569.3 OAJ22982.1 - 1.8 7.2 11.3 3.1 6.4 7.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BLVR PF06375.6 OAJ22982.1 - 3.5 7.4 19.6 0.27 11.0 6.9 2.9 3 0 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) U79_P34 PF03064.11 OAJ22982.1 - 5.2 6.5 13.3 16 4.8 9.2 1.8 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DEAD PF00270.24 OAJ22983.1 - 4e-20 71.9 0.0 4.4e-14 52.3 0.0 3.5 3 0 0 3 3 3 3 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ22983.1 - 6.5e-05 22.7 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ22983.1 - 0.0005 19.9 0.3 0.0012 18.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PAP_assoc PF03828.14 OAJ22984.1 - 8.4e-15 54.4 0.0 2.1e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 OAJ22984.1 - 1.8e-08 34.5 0.0 3.7e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DEAD PF00270.24 OAJ22985.1 - 4.7e-45 153.1 0.0 2.2e-44 150.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ22985.1 - 7.7e-24 83.3 0.0 3.7e-23 81.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 OAJ22985.1 - 0.01 14.6 0.0 0.029 13.1 0.0 1.5 1 1 0 2 2 2 0 SNF2 family N-terminal domain YqgF PF14639.1 OAJ22985.1 - 0.26 10.8 3.0 7.5 6.1 0.2 3.0 2 1 1 3 3 3 0 Holliday-junction resolvase-like of SPT6 UBN2 PF14223.1 OAJ22986.1 - 3.1e-05 23.7 0.0 5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ22986.1 - 0.0018 18.0 6.0 0.0033 17.2 4.2 1.5 1 0 0 1 1 1 1 Zinc knuckle UBN2_2 PF14227.1 OAJ22986.1 - 0.054 13.0 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVT_2 PF07727.9 OAJ22987.1 - 3.4e-79 265.2 0.0 4.9e-79 264.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ22987.1 - 2.5e-25 88.8 0.0 6.3e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ22987.1 - 2.1e-07 30.4 0.0 4.8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ22987.1 - 9.3e-05 21.8 0.0 0.00023 20.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Meckelin PF09773.4 OAJ22987.1 - 0.017 12.9 0.1 0.023 12.4 0.1 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) WD40 PF00400.27 OAJ22988.1 - 1.9e-38 128.9 22.8 1.9e-07 30.6 0.0 10.5 11 0 0 11 11 11 6 WD domain, G-beta repeat Utp12 PF04003.7 OAJ22988.1 - 4.4e-15 55.5 0.2 1.6e-07 31.1 0.0 2.6 3 0 0 3 3 3 2 Dip2/Utp12 Family PQQ_2 PF13360.1 OAJ22988.1 - 0.0023 17.4 0.0 0.048 13.1 0.0 2.8 1 1 1 2 2 2 1 PQQ-like domain Nup160 PF11715.3 OAJ22988.1 - 0.0028 15.8 0.0 5.2 5.0 0.0 3.5 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 OAJ22988.1 - 0.0063 14.8 0.1 1 7.5 0.0 3.5 4 1 0 4 4 4 1 Cytochrome D1 heme domain DUF1513 PF07433.6 OAJ22988.1 - 0.0089 14.9 0.2 0.48 9.2 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1513) PQQ PF01011.16 OAJ22988.1 - 0.029 13.9 0.2 3.4 7.3 0.0 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat Baculo_PEP_C PF04513.7 OAJ22993.1 - 1.8 8.3 6.4 1.5 8.6 0.7 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Aminotran_3 PF00202.16 OAJ22994.1 - 5.9e-98 327.8 0.1 7.1e-98 327.5 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 OAJ22994.1 - 2.2e-05 23.6 0.0 0.0015 17.5 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class I and II POP1 PF06978.6 OAJ22995.1 - 4.1e-31 108.1 13.6 4.1e-31 108.1 9.4 3.9 4 0 0 4 4 4 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 OAJ22995.1 - 7.2e-10 38.5 6.4 2.1e-06 27.4 0.0 3.7 3 0 0 3 3 3 2 POPLD (NUC188) domain NADH-u_ox-rdase PF10785.4 OAJ22996.1 - 9.9e-31 105.8 0.1 1.5e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 OAJ22996.1 - 3.4e-11 42.6 0.0 5.4e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Acyl_transf_3 PF01757.17 OAJ22996.1 - 0.0057 15.5 0.8 0.0076 15.1 0.5 1.1 1 0 0 1 1 1 1 Acyltransferase family TPR_11 PF13414.1 OAJ22997.1 - 1.1e-09 37.7 24.0 6.4e-05 22.5 0.0 9.2 8 2 1 10 10 10 4 TPR repeat TPR_1 PF00515.23 OAJ22997.1 - 1.2e-09 37.2 18.0 0.24 11.1 0.0 8.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ22997.1 - 6.9e-08 31.8 26.3 0.088 12.7 0.1 10.1 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ22997.1 - 8.4e-08 32.4 27.8 0.35 11.2 0.0 9.0 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ22997.1 - 1.4e-07 31.1 2.9 6.6 7.2 0.2 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ22997.1 - 2.2e-07 30.7 18.6 0.00012 21.9 0.0 8.5 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ22997.1 - 2.1e-06 27.1 5.3 0.92 9.4 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ22997.1 - 0.0026 18.2 0.9 0.0026 18.2 0.6 12.2 13 1 0 13 13 13 3 Tetratricopeptide repeat Apc3 PF12895.2 OAJ22997.1 - 0.0068 16.5 4.6 0.14 12.2 0.0 4.7 6 1 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 OAJ22997.1 - 0.013 15.8 0.3 0.013 15.8 0.2 10.3 12 0 0 12 12 12 0 Tetratricopeptide repeat ubiquitin PF00240.18 OAJ22999.1 - 3e-34 116.2 1.1 3e-34 116.2 0.7 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.14 OAJ22999.1 - 3.4e-26 90.7 0.7 7e-26 89.7 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 OAJ22999.1 - 8.7e-20 70.1 0.8 1.5e-19 69.4 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAJ22999.1 - 2.4e-06 27.7 0.5 4.6e-05 23.5 0.1 2.6 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAJ22999.1 - 0.0002 21.0 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 OAJ22999.1 - 0.00057 19.7 0.7 0.0012 18.7 0.5 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 OAJ22999.1 - 0.004 17.3 0.6 0.0054 16.8 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2207 PF09972.4 OAJ22999.1 - 0.0062 15.1 0.3 0.0072 14.9 0.2 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) IBR PF01485.16 OAJ22999.1 - 0.016 15.0 0.8 0.027 14.3 0.6 1.4 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 OAJ22999.1 - 0.041 13.9 0.8 0.096 12.7 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 OAJ22999.1 - 0.077 11.3 3.3 0.66 8.2 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Macoilin PF09726.4 OAJ23000.1 - 0.47 8.6 3.9 0.74 8.0 2.7 1.2 1 0 0 1 1 1 0 Transmembrane protein SSP160 PF06933.6 OAJ23000.1 - 9.1 4.1 22.3 15 3.4 15.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 efThoc1 PF11957.3 OAJ23001.1 - 4.3e-53 180.5 10.7 5.1e-48 163.8 3.9 5.2 2 1 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Ribosomal_60s PF00428.14 OAJ23001.1 - 0.013 15.8 8.1 0.013 15.8 5.6 6.5 6 2 1 7 7 7 0 60s Acidic ribosomal protein RRM_1 PF00076.17 OAJ23002.1 - 1.1e-15 57.0 0.1 1.8e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ23002.1 - 1e-12 47.8 0.0 2e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ23002.1 - 4.9e-08 32.7 0.0 7.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ23002.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif MR_MLE PF01188.16 OAJ23002.1 - 0.097 13.2 0.1 0.19 12.2 0.0 1.5 1 1 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Ribonuc_P_40 PF08584.6 OAJ23004.1 - 1.1e-34 119.7 0.0 2.7e-20 72.5 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit Myc_N PF01056.13 OAJ23004.1 - 0.6 9.2 5.8 1 8.4 4.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.9 OAJ23004.1 - 1.3 6.9 12.0 2 6.3 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 OAJ23004.1 - 2.2 7.9 14.2 0.17 11.5 6.3 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 OAJ23004.1 - 2.2 6.0 9.9 3.3 5.5 6.9 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C2H2_4 PF13894.1 OAJ23006.1 - 0.062 13.6 9.3 0.93 9.9 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger SSP160 PF06933.6 OAJ23006.1 - 0.12 10.3 3.3 0.14 10.1 2.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-C2H2 PF00096.21 OAJ23006.1 - 1.5 9.3 14.0 2.3 8.7 0.6 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type UBN2_2 PF14227.1 OAJ23007.1 - 3.8e-12 45.8 0.0 6.9e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ23007.1 - 0.00016 21.4 0.1 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ23007.1 - 0.00027 20.7 4.9 0.00027 20.7 3.4 2.1 2 0 0 2 2 2 1 Zinc knuckle DUF4219 PF13961.1 OAJ23007.1 - 0.0009 18.6 0.1 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) zf-CCHC_2 PF13696.1 OAJ23007.1 - 0.007 15.8 3.0 0.018 14.4 2.0 1.7 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.3 OAJ23007.1 - 0.19 11.6 5.0 0.83 9.5 0.9 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G UQ_con PF00179.21 OAJ23008.1 - 9.9e-17 60.6 0.0 1.1e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 OAJ23008.1 - 0.004 17.0 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 OAJ23008.1 - 0.12 12.0 0.1 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 UEV domain DNA_pol_B PF00136.16 OAJ23009.1 - 1.4e-114 383.5 0.0 1.8e-114 383.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 OAJ23009.1 - 1.6e-51 174.3 0.0 2.8e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 OAJ23009.1 - 1e-28 100.1 0.0 1.7e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 OAJ23009.1 - 6.9e-23 80.2 3.9 2e-22 78.7 2.7 1.9 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal BAR PF03114.13 OAJ23010.1 - 5.5e-40 137.2 0.7 9.1e-40 136.5 0.5 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 OAJ23010.1 - 2.1e-16 59.0 0.0 3.8e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ23010.1 - 1e-12 47.4 0.1 1.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ23010.1 - 3.7e-11 42.3 0.0 8.6e-11 41.1 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain FAM92 PF06730.6 OAJ23010.1 - 0.004 16.5 0.8 0.007 15.7 0.5 1.3 1 0 0 1 1 1 1 FAM92 protein BLYB PF05289.6 OAJ23010.1 - 0.045 13.5 0.1 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein Spt20 PF12090.3 OAJ23010.1 - 1.2 8.4 4.7 5.2 6.3 0.9 2.2 2 0 0 2 2 2 0 Spt20 family Med3 PF11593.3 OAJ23010.1 - 8.5 5.5 24.7 1.6 7.8 7.6 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal F-box-like PF12937.2 OAJ23011.1 - 0.052 13.2 0.0 0.46 10.2 0.0 2.6 2 0 0 2 2 2 0 F-box-like Dimer_Tnp_hAT PF05699.9 OAJ23018.1 - 2.7e-09 36.5 0.0 6.1e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Chs3p PF12271.3 OAJ23020.1 - 1.9e-20 73.0 0.8 7.2e-10 38.3 0.1 2.1 2 0 0 2 2 2 2 Chitin synthase III catalytic subunit POM121 PF15229.1 OAJ23020.1 - 0.024 14.0 1.1 0.033 13.6 0.7 1.1 1 0 0 1 1 1 0 POM121 family WTF PF03303.8 OAJ23020.1 - 0.096 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 WTF protein DNA_pol_E_B PF04042.11 OAJ23021.1 - 6.2e-41 139.9 0.0 1.4e-40 138.7 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Sugar_tr PF00083.19 OAJ23022.1 - 2.4e-120 402.1 23.3 2.8e-120 401.9 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ23022.1 - 2.3e-21 75.9 41.2 2.8e-20 72.3 8.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_45 PF02015.11 OAJ23023.1 - 1.9e-49 168.4 10.0 2.2e-49 168.2 6.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Glyco_hydro_45 PF02015.11 OAJ23024.1 - 1.6e-24 87.0 0.8 2.3e-24 86.6 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 ATP-synt_ab_N PF02874.18 OAJ23025.1 - 6.8e-06 26.2 0.4 1.3e-05 25.3 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain SIR2 PF02146.12 OAJ23025.1 - 1.6e-05 24.7 0.0 2.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family RVT_2 PF07727.9 OAJ23026.1 - 6.2e-76 254.6 0.0 8.2e-76 254.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 OAJ23026.1 - 0.069 12.9 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Reverse transcriptase-like MFS_1 PF07690.11 OAJ23027.1 - 9.2e-46 156.1 46.7 9.2e-46 156.1 32.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Septin PF00735.13 OAJ23028.1 - 2.7e-123 410.4 0.1 2.7e-123 410.4 0.1 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 OAJ23028.1 - 4.5e-07 29.8 0.0 1.3e-06 28.3 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 OAJ23028.1 - 2.3e-06 26.8 0.0 5.8e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 OAJ23028.1 - 3.3e-05 23.3 0.5 0.00051 19.5 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.17 OAJ23028.1 - 0.0003 20.2 0.3 0.0032 16.8 0.0 2.4 2 0 0 2 2 2 1 Ras family AAA_10 PF12846.2 OAJ23028.1 - 0.00047 19.6 0.0 0.00077 18.9 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 OAJ23028.1 - 0.0015 18.6 0.0 0.015 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.11 OAJ23028.1 - 0.0018 17.3 1.4 0.0039 16.3 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 OAJ23028.1 - 0.0033 17.9 0.2 0.021 15.3 0.0 2.4 2 1 0 2 2 2 1 Miro-like protein Arch_ATPase PF01637.13 OAJ23028.1 - 0.0033 17.1 1.7 1.5 8.4 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase Dynamin_N PF00350.18 OAJ23028.1 - 0.0041 16.9 6.2 0.063 13.0 0.0 3.3 2 2 0 3 3 3 1 Dynamin family AAA_16 PF13191.1 OAJ23028.1 - 0.0042 17.0 0.3 0.022 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 OAJ23028.1 - 0.0047 17.2 7.5 0.94 9.7 5.2 2.6 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 OAJ23028.1 - 0.008 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 OAJ23028.1 - 0.03 14.4 0.1 0.36 11.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 OAJ23028.1 - 0.03 14.0 0.1 0.1 12.2 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 OAJ23028.1 - 0.033 13.7 0.0 0.082 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAJ23028.1 - 0.061 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 OAJ23028.1 - 0.11 11.9 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Exonuc_VII_L PF02601.10 OAJ23028.1 - 0.19 10.8 7.2 0.4 9.8 5.0 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_5 PF07728.9 OAJ23028.1 - 0.21 11.3 1.5 1.5 8.5 0.0 2.8 3 1 1 4 4 3 0 AAA domain (dynein-related subfamily) YlqD PF11068.3 OAJ23028.1 - 0.38 10.7 8.7 1.1 9.3 6.0 1.8 1 0 0 1 1 1 0 YlqD protein DUF87 PF01935.12 OAJ23028.1 - 0.43 10.3 5.4 2 8.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 ArgK PF03308.11 OAJ23028.1 - 1 8.1 3.0 10 4.7 0.0 2.3 2 0 0 2 2 2 0 ArgK protein ATP_bind_1 PF03029.12 OAJ23028.1 - 1.5 8.2 4.5 19 4.6 0.0 3.2 4 1 0 4 4 4 0 Conserved hypothetical ATP binding protein IncA PF04156.9 OAJ23028.1 - 2 8.0 8.2 3.6 7.1 5.7 1.4 1 0 0 1 1 1 0 IncA protein Strep_SA_rep PF06696.6 OAJ23028.1 - 4 7.3 5.8 4.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Vps26 PF03643.10 OAJ23029.1 - 5e-130 432.2 3.6 5.8e-130 432.0 2.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 OAJ23029.1 - 0.022 14.5 1.2 2 8.2 0.1 3.4 3 1 0 4 4 4 0 Arrestin (or S-antigen), N-terminal domain COX16 PF14138.1 OAJ23031.1 - 1.1e-24 86.3 0.1 2e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Evr1_Alr PF04777.8 OAJ23031.1 - 4.3e-24 84.2 0.0 1.3e-23 82.7 0.0 1.8 2 0 0 2 2 2 1 Erv1 / Alr family KH_1 PF00013.24 OAJ23032.1 - 1.3e-42 143.1 9.0 4e-16 58.3 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 OAJ23032.1 - 5e-31 105.7 15.0 2.5e-10 39.7 1.4 3.8 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 OAJ23032.1 - 4.8e-15 54.8 7.0 2.5e-05 23.7 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 OAJ23032.1 - 3.3e-06 26.6 1.8 0.64 9.7 0.0 3.4 3 0 0 3 3 3 3 KH domain CEP170_C PF15308.1 OAJ23032.1 - 0.0085 14.4 13.7 0.011 14.0 9.5 1.1 1 0 0 1 1 1 1 CEP170 C-terminus KH_5 PF13184.1 OAJ23032.1 - 0.01 15.5 5.0 1.5 8.6 0.1 3.5 3 0 0 3 3 3 0 NusA-like KH domain zf-CHY PF05495.7 OAJ23033.1 - 1.7e-14 53.7 14.0 2.5e-14 53.1 9.7 1.2 1 0 0 1 1 1 1 CHY zinc finger Zn-ribbon_8 PF09723.5 OAJ23033.1 - 0.046 13.6 10.0 0.052 13.5 1.3 2.6 2 0 0 2 2 2 0 Zinc ribbon domain MoCo_carrier PF12694.2 OAJ23033.1 - 0.095 12.1 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Putative molybdenum carrier Evr1_Alr PF04777.8 OAJ23033.1 - 0.29 11.0 4.5 0.62 9.9 3.0 1.7 1 1 0 1 1 1 0 Erv1 / Alr family Elf1 PF05129.8 OAJ23033.1 - 0.71 9.5 9.2 0.11 12.1 3.3 1.8 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-HYPF PF07503.7 OAJ23033.1 - 1.1 8.7 6.8 0.12 11.8 0.9 2.1 2 0 0 2 2 2 0 HypF finger DZR PF12773.2 OAJ23033.1 - 1.2 9.0 9.3 0.72 9.7 4.5 2.1 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 OAJ23033.1 - 2.3 7.9 8.9 0.22 11.2 1.1 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family C1_4 PF07975.7 OAJ23033.1 - 2.7 8.0 9.2 4.2 7.4 5.0 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 OAJ23033.1 - 3.3 7.5 10.4 28 4.6 5.5 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 OAJ23033.1 - 8.7 6.0 13.0 55 3.4 5.1 3.4 2 1 0 2 2 2 0 zinc-ribbon domain Sugar_tr PF00083.19 OAJ23034.1 - 2.9e-86 289.8 19.1 4.6e-71 239.7 3.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ23034.1 - 7.2e-22 77.5 15.6 7.2e-22 77.5 10.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily RRM_1 PF00076.17 OAJ23038.1 - 9.6e-46 153.2 0.0 1.8e-22 78.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ23038.1 - 2.8e-38 129.7 0.0 1.6e-18 66.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ23038.1 - 8.2e-19 67.2 0.0 1.4e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ23038.1 - 2.9e-05 23.8 0.0 0.11 12.3 0.0 2.6 2 1 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 OAJ23038.1 - 0.009 15.7 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 OAJ23038.1 - 0.048 13.2 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Calcipressin SNAP PF14938.1 OAJ23039.1 - 4e-93 311.6 11.8 4.5e-93 311.4 8.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 OAJ23039.1 - 1.3e-07 31.1 16.9 0.00023 20.7 1.5 3.8 1 1 3 4 4 4 4 TPR repeat TPR_12 PF13424.1 OAJ23039.1 - 6.5e-06 25.9 13.9 0.004 17.0 0.4 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ23039.1 - 0.00038 21.0 26.5 0.0048 17.5 1.5 4.6 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ23039.1 - 0.0073 16.6 17.8 17 6.1 0.2 6.6 5 2 1 6 6 6 0 Tetratricopeptide repeat Spatacsin_C PF14649.1 OAJ23039.1 - 0.0085 14.9 3.1 0.17 10.7 0.4 2.2 1 1 0 2 2 2 2 Spatacsin C-terminus TPR_9 PF13371.1 OAJ23039.1 - 0.011 15.5 5.2 1.4 8.8 0.1 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat PerC PF06069.6 OAJ23039.1 - 0.027 14.5 0.7 1.8 8.6 0.1 2.6 2 1 1 3 3 3 0 PerC transcriptional activator DUF4170 PF13773.1 OAJ23039.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4170) TPR_2 PF07719.12 OAJ23039.1 - 0.31 11.0 20.4 4.8 7.3 0.1 7.1 3 3 5 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ23039.1 - 0.34 10.7 13.3 3.3 7.7 0.1 5.5 4 2 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ23039.1 - 1.1 10.0 14.4 5.7 7.8 0.1 5.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ23039.1 - 2.4 7.9 18.4 3.5 7.4 0.1 6.7 6 2 2 8 8 8 0 Tetratricopeptide repeat Bud13 PF09736.4 OAJ23040.1 - 2.3e-43 147.9 4.3 2.3e-43 147.9 3.0 2.5 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex RRM_1 PF00076.17 OAJ23041.1 - 6.7e-48 160.2 0.0 1.2e-22 79.2 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ23041.1 - 1.6e-37 127.2 0.0 1.6e-18 66.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ23041.1 - 2.4e-21 75.3 0.0 6.5e-10 38.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ23041.1 - 6.9e-06 25.8 8.4 0.013 15.3 0.0 3.8 4 0 0 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.1 OAJ23041.1 - 0.017 14.8 0.0 4.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif 4HBT_3 PF13622.1 OAJ23042.1 - 1.2e-23 84.1 0.8 3.7e-23 82.5 0.6 1.7 1 1 0 1 1 1 1 Thioesterase-like superfamily FAD_binding_4 PF01565.18 OAJ23043.1 - 4.8e-26 90.9 4.6 6.7e-26 90.4 1.8 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 OAJ23043.1 - 2.1e-06 27.5 0.2 3.9e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like XPG_I_2 PF12813.2 OAJ23045.1 - 8.9e-06 25.3 0.0 4.2e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 XPG domain containing XPG_N PF00752.12 OAJ23045.1 - 0.0059 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 OAJ23045.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 XPG I-region K_channel_TID PF07941.6 OAJ23045.1 - 0.067 13.4 4.8 0.27 11.5 3.3 2.0 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF2057 PF09829.4 OAJ23045.1 - 0.17 11.5 0.3 0.37 10.4 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) WWbp PF10349.4 OAJ23046.1 - 0.047 14.5 3.2 0.17 12.7 2.2 1.9 1 1 0 1 1 1 0 WW-domain ligand protein NTPase_P4 PF11602.3 OAJ23047.1 - 0.13 11.2 1.1 0.14 11.1 0.8 1.0 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 Pkinase PF00069.20 OAJ23048.1 - 2.1e-71 240.1 0.0 2.9e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ23048.1 - 8.2e-35 120.1 0.0 1.5e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ23048.1 - 0.00042 19.3 0.0 0.0012 17.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAJ23048.1 - 0.0016 18.2 0.0 0.0069 16.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAJ23048.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 OAJ23048.1 - 0.026 13.5 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Asp PF00026.18 OAJ23049.1 - 1.6e-27 96.6 0.0 2.5e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 OAJ23049.1 - 6.1e-06 26.6 0.1 0.00093 19.6 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease DUF2962 PF11176.3 OAJ23050.1 - 3.4e-38 130.6 0.0 4.3e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) HTH_32 PF13565.1 OAJ23050.1 - 0.68 10.7 3.5 0.3 11.9 0.2 2.0 2 0 0 2 2 2 0 Homeodomain-like domain AIP3 PF03915.8 OAJ23051.1 - 2.7e-96 323.0 0.0 5.4e-96 322.0 0.0 1.5 1 1 0 1 1 1 1 Actin interacting protein 3 Syntaxin_2 PF14523.1 OAJ23051.1 - 0.019 14.9 0.4 10 6.2 0.0 3.1 3 0 0 3 3 3 0 Syntaxin-like protein Halo_GVPC PF05465.8 OAJ23051.1 - 0.046 13.6 2.1 1.5 8.8 0.1 2.8 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Spc97_Spc98 PF04130.8 OAJ23053.1 - 5.3e-36 124.0 0.0 3.7e-17 61.8 0.0 2.3 2 0 0 2 2 2 2 Spc97 / Spc98 family DHHW PF14286.1 OAJ23053.1 - 0.56 9.4 0.1 0.88 8.8 0.1 1.1 1 0 0 1 1 1 0 DHHW protein DNA_pol_phi PF04931.8 OAJ23053.1 - 8 4.0 8.5 12 3.4 5.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Glyco_tranf_2_3 PF13641.1 OAJ23059.1 - 2.1e-19 70.2 0.5 2.9e-15 56.7 0.2 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 OAJ23059.1 - 1.9e-12 47.3 6.5 1.9e-12 47.3 4.5 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.10 OAJ23059.1 - 2.9e-11 42.4 5.9 1.4e-09 36.8 3.3 3.1 2 1 0 2 2 2 1 Chitin synthase Glyco_transf_21 PF13506.1 OAJ23059.1 - 1.7e-10 40.4 0.1 4.7e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 OAJ23059.1 - 3.3e-05 23.6 0.0 0.066 12.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 IncA PF04156.9 OAJ23061.1 - 0.54 9.8 4.3 1.2 8.7 0.9 2.1 2 0 0 2 2 2 0 IncA protein Herpes_capsid PF06112.6 OAJ23062.1 - 0.063 13.3 8.9 0.073 13.1 6.2 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF4218 PF13960.1 OAJ23063.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Glyco_hydro_16 PF00722.16 OAJ23064.1 - 6.1e-15 54.9 2.0 9.3e-15 54.3 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF3505 PF12013.3 OAJ23065.1 - 2.1e-06 27.9 0.0 2.5e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) RHIM PF12721.2 OAJ23065.1 - 0.082 13.3 2.1 0.95 9.9 0.0 2.6 3 0 0 3 3 3 0 RIP homotypic interaction motif Prefoldin_2 PF01920.15 OAJ23066.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Prefoldin subunit Transposase_21 PF02992.9 OAJ23067.1 - 1.3e-24 86.5 0.0 2.2e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 HA2 PF04408.18 OAJ23068.1 - 4.7e-28 97.1 0.4 8.6e-28 96.3 0.3 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 OAJ23068.1 - 1.3e-24 86.2 0.0 2.6e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 OAJ23068.1 - 7.4e-11 41.7 0.0 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ23068.1 - 6.1e-07 29.0 0.0 1.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ23068.1 - 2.3e-06 27.7 0.0 5.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 OAJ23068.1 - 0.011 15.5 0.0 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit KaiC PF06745.8 OAJ23068.1 - 0.018 14.1 0.0 0.13 11.3 0.0 2.2 2 0 0 2 2 2 0 KaiC T2SE PF00437.15 OAJ23068.1 - 0.02 13.8 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.17 OAJ23068.1 - 0.023 14.1 0.1 0.092 12.1 0.0 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 OAJ23068.1 - 0.027 14.0 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 OAJ23068.1 - 0.05 13.9 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 OAJ23068.1 - 0.092 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRF-TF PF00319.13 OAJ23068.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) ABC_tran PF00005.22 OAJ23068.1 - 0.17 12.1 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 OAJ23068.1 - 0.23 10.6 0.0 0.52 9.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FAR1 PF03101.10 OAJ23069.1 - 0.011 16.1 0.2 0.019 15.4 0.1 1.3 1 0 0 1 1 1 0 FAR1 DNA-binding domain F-box PF00646.28 OAJ23070.1 - 1.8e-07 30.6 0.3 3.7e-07 29.6 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ23070.1 - 0.00012 21.7 1.8 0.00016 21.3 0.1 2.1 3 0 0 3 3 3 1 F-box-like PRELI PF04707.9 OAJ23071.1 - 2e-32 111.9 0.0 3.6e-24 85.1 0.0 2.0 2 0 0 2 2 2 2 PRELI-like family Clathrin_lg_ch PF01086.12 OAJ23072.1 - 1.9e-32 113.0 15.6 5.8e-29 101.6 10.8 2.3 1 1 0 1 1 1 1 Clathrin light chain UCH PF00443.24 OAJ23073.1 - 3.5e-52 177.1 0.0 5.3e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ23073.1 - 4e-26 92.1 0.0 7.4e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4590 PF15257.1 OAJ23074.1 - 0.05 13.4 0.8 0.065 13.0 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) zf-C3HC4_4 PF15227.1 OAJ23074.1 - 0.63 9.9 5.0 3.1 7.7 3.3 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Furin-like PF00757.15 OAJ23074.1 - 3.3 7.3 10.8 4.1 7.0 7.5 1.1 1 0 0 1 1 1 0 Furin-like cysteine rich region Cid2 PF09774.4 OAJ23075.1 - 6.8e-23 81.4 0.1 6.3e-21 75.0 0.1 2.2 1 1 0 1 1 1 1 Caffeine-induced death protein 2 SR-25 PF10500.4 OAJ23076.1 - 0.0015 18.0 7.4 0.002 17.6 5.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Acyl-thio_N PF12590.3 OAJ23076.1 - 0.003 18.0 4.1 0.0053 17.2 2.8 1.4 1 0 0 1 1 1 1 Acyl-ATP thioesterase Saccharop_dh_N PF04455.7 OAJ23076.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region Spore_YtfJ PF09579.5 OAJ23076.1 - 0.75 9.6 5.4 9 6.2 0.7 2.3 1 1 1 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) Lyase_1 PF00206.15 OAJ23083.1 - 7.1e-22 77.9 0.0 1.1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 OAJ23083.1 - 3.6e-16 58.9 0.0 8.2e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus RNA_pol_L_2 PF13656.1 OAJ23084.1 - 8.8e-28 95.5 0.0 1.2e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 OAJ23084.1 - 9.7e-09 34.2 0.0 1.3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain mit_SMPDase PF14724.1 OAJ23084.1 - 0.023 12.5 0.0 0.026 12.3 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase zf-C2H2 PF00096.21 OAJ23084.1 - 0.065 13.6 0.5 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type ABC_ATPase PF09818.4 OAJ23084.1 - 0.11 11.0 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class PEP-utilisers_N PF05524.8 OAJ23084.1 - 0.12 12.1 2.4 0.42 10.4 0.1 2.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal MFS_1 PF07690.11 OAJ23086.1 - 3.6e-28 98.3 27.9 1.3e-27 96.4 19.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 OAJ23086.1 - 3.9 7.6 13.5 3 7.9 1.1 3.6 3 1 2 5 5 5 0 NfeD-like C-terminal, partner-binding Med13_C PF06333.7 OAJ23087.1 - 5.8e-07 28.3 0.0 1.8e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal G-patch_2 PF12656.2 OAJ23088.1 - 4.4e-25 87.3 0.3 4.4e-25 87.3 0.2 2.9 3 1 1 4 4 4 1 DExH-box splicing factor binding site G-patch PF01585.18 OAJ23088.1 - 3.5e-06 26.6 3.2 6.7e-06 25.7 2.2 1.5 1 0 0 1 1 1 1 G-patch domain CAS_CSE1 PF03378.10 OAJ23089.1 - 6.3e-120 400.4 0.0 1.1e-119 399.6 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 OAJ23089.1 - 1.6e-117 392.1 0.0 2.7e-117 391.4 0.0 1.4 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 OAJ23089.1 - 5.7e-09 35.7 0.4 1.1e-06 28.4 0.3 3.3 3 1 0 3 3 3 1 Importin-beta N-terminal domain HEAT PF02985.17 OAJ23089.1 - 4.9 7.5 8.0 22 5.4 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat CH PF00307.26 OAJ23090.1 - 2.4e-40 136.9 0.2 6.2e-22 77.6 0.1 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 OAJ23090.1 - 3.1e-18 65.5 0.0 8.8e-18 64.0 0.0 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 OAJ23090.1 - 1e-13 50.6 0.1 9.3e-10 38.0 0.1 2.5 2 0 0 2 2 2 2 CAMSAP CH domain Tektin PF03148.9 OAJ23090.1 - 0.00095 17.8 0.3 0.0016 17.0 0.2 1.3 1 0 0 1 1 1 1 Tektin family Med29 PF11568.3 OAJ23090.1 - 0.088 12.8 0.5 6.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Mediator complex subunit 29 EF-hand_6 PF13405.1 OAJ23090.1 - 0.089 12.7 0.0 1.2 9.1 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain Spectrin PF00435.16 OAJ23090.1 - 0.26 11.5 4.2 1.9 8.8 0.3 3.1 2 1 0 2 2 2 0 Spectrin repeat Baculo_PEP_C PF04513.7 OAJ23090.1 - 0.6 9.9 3.7 0.81 9.5 1.4 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Redoxin PF08534.5 OAJ23091.1 - 5e-29 100.7 0.1 5.7e-29 100.5 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAJ23091.1 - 5.4e-12 45.4 0.0 7.1e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DHHW PF14286.1 OAJ23092.1 - 0.23 10.7 5.2 0.027 13.7 0.4 1.7 2 0 0 2 2 2 0 DHHW protein M20_dimer PF07687.9 OAJ23094.1 - 5.6e-09 35.7 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 OAJ23094.1 - 3.8e-08 33.0 0.2 5.6e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 NKWYS PF10364.4 OAJ23094.1 - 0.044 13.5 0.3 0.076 12.7 0.2 1.3 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein HCNGP PF07818.8 OAJ23095.1 - 5.7e-18 64.7 0.0 1.1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 HCNGP-like protein PRP38_assoc PF12871.2 OAJ23095.1 - 0.0019 18.6 34.9 0.0025 18.3 16.8 2.3 2 0 0 2 2 2 2 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Paramyxo_ncap PF00973.14 OAJ23095.1 - 0.1 11.2 9.0 0.15 10.7 6.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Apt1 PF10351.4 OAJ23095.1 - 0.18 10.6 5.7 0.25 10.1 3.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Glycos_transf_2 PF00535.21 OAJ23096.1 - 5.5e-29 101.0 0.0 7.1e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 OAJ23096.1 - 9.2e-13 48.5 0.0 1.8e-12 47.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 OAJ23096.1 - 5.1e-06 25.7 0.0 7e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 OAJ23096.1 - 0.0011 18.3 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_7N PF13733.1 OAJ23096.1 - 0.007 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_trans_2_3 PF13632.1 OAJ23096.1 - 0.02 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.1 OAJ23096.1 - 0.044 14.1 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 SR-25 PF10500.4 OAJ23097.1 - 0.017 14.6 7.9 0.02 14.3 5.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 OAJ23097.1 - 0.58 10.2 7.7 0.8 9.7 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Med3 PF11593.3 OAJ23097.1 - 2.9 7.0 13.1 3.3 6.8 9.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NST1 PF13945.1 OAJ23102.1 - 9.5e-50 169.3 0.0 9.5e-50 169.3 0.0 8.9 7 2 1 9 9 9 2 Salt tolerance down-regulator TFIIA PF03153.8 OAJ23102.1 - 2.6e-05 24.3 21.3 2.6e-05 24.3 14.8 9.1 4 2 3 7 7 7 2 Transcription factor IIA, alpha/beta subunit Nsp1_C PF05064.8 OAJ23103.1 - 1e-20 73.4 0.0 3.2e-20 71.9 0.0 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region CDC45 PF02724.9 OAJ23107.1 - 0.00035 18.7 10.4 0.00035 18.7 7.2 1.1 1 0 0 1 1 1 1 CDC45-like protein SGT1 PF07093.6 OAJ23107.1 - 0.0069 14.8 8.4 0.0054 15.1 5.8 1.2 1 0 0 1 1 1 1 SGT1 protein BUD22 PF09073.5 OAJ23107.1 - 0.018 14.1 14.4 0.021 13.8 10.0 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 OAJ23107.1 - 0.023 12.6 25.3 0.031 12.2 17.5 1.2 1 0 0 1 1 1 0 Nop14-like family PhnA_Zn_Ribbon PF08274.7 OAJ23107.1 - 0.037 13.8 4.9 0.26 11.0 0.3 2.7 2 0 0 2 2 2 0 PhnA Zinc-Ribbon eIF-3c_N PF05470.7 OAJ23107.1 - 0.19 9.7 8.2 0.19 9.8 5.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Tim54 PF11711.3 OAJ23107.1 - 0.26 9.8 2.3 0.31 9.5 1.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Prog_receptor PF02161.10 OAJ23107.1 - 0.39 9.4 5.1 0.48 9.1 3.5 1.1 1 0 0 1 1 1 0 Progesterone receptor SAPS PF04499.10 OAJ23107.1 - 0.66 8.5 3.5 0.59 8.7 2.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Vfa1 PF08432.5 OAJ23107.1 - 0.76 9.7 11.1 1.3 9.0 7.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 YqfQ PF14181.1 OAJ23107.1 - 1.9 8.4 7.4 2.6 8.0 5.1 1.2 1 0 0 1 1 1 0 YqfQ-like protein Polyoma_lg_T_C PF06431.6 OAJ23107.1 - 2.8 6.5 7.4 3.8 6.0 5.2 1.4 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus CDC27 PF09507.5 OAJ23107.1 - 3.5 6.7 12.7 3.4 6.7 8.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sporozoite_P67 PF05642.6 OAJ23107.1 - 7.5 4.2 15.6 11 3.6 10.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Paf1 PF03985.8 OAJ23107.1 - 9.7 4.8 22.2 14 4.2 15.4 1.2 1 0 0 1 1 1 0 Paf1 HSP90 PF00183.13 OAJ23107.1 - 9.8 4.4 17.8 13 4.0 12.3 1.2 1 0 0 1 1 1 0 Hsp90 protein CAS_CSE1 PF03378.10 OAJ23108.1 - 0.00024 19.5 0.4 0.0021 16.4 0.1 1.9 1 1 1 2 2 2 2 CAS/CSE protein, C-terminus IL22 PF14565.1 OAJ23108.1 - 0.12 12.4 0.1 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor E1-E2_ATPase PF00122.15 OAJ23113.1 - 6.6e-61 205.2 0.6 2.4e-60 203.4 0.4 2.1 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 OAJ23113.1 - 4.7e-25 89.2 0.2 9.2e-25 88.3 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAJ23113.1 - 1.4e-12 48.1 0.0 3.3e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAJ23113.1 - 1.2e-10 40.7 0.9 2.5e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 OAJ23113.1 - 0.00043 19.9 0.1 0.00043 19.9 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ23113.1 - 0.048 13.6 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit F-box PF00646.28 OAJ23114.1 - 8.5e-08 31.6 0.0 1.7e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 OAJ23114.1 - 0.016 14.8 0.2 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 F-box-like domain mRNA_cap_enzyme PF01331.14 OAJ23115.1 - 4e-48 163.6 0.3 5.3e-48 163.2 0.2 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 OAJ23115.1 - 4.3e-14 52.7 0.0 5.2e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 OAJ23115.1 - 1.1e-07 31.4 0.1 2.9e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Flu_PB1 PF00602.12 OAJ23115.1 - 0.082 10.6 0.1 0.12 10.1 0.1 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 Syndecan PF01034.15 OAJ23116.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain IPK PF03770.11 OAJ23117.1 - 3.2e-52 177.0 0.0 1.1e-51 175.2 0.0 1.9 2 0 0 2 2 2 1 Inositol polyphosphate kinase Pkinase PF00069.20 OAJ23120.1 - 6.1e-61 205.8 0.0 8.4e-61 205.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ23120.1 - 4.9e-39 133.9 0.0 6.5e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ23120.1 - 1.2e-05 24.3 0.0 2.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Sororin PF09666.5 OAJ23120.1 - 0.0041 17.3 1.3 0.0072 16.5 0.5 1.6 1 1 0 1 1 1 1 Sororin protein Dicty_REP PF05086.7 OAJ23121.1 - 0.87 7.2 9.1 1.8 6.2 6.3 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Chitin_synth_1 PF01644.12 OAJ23123.1 - 8.7e-86 285.7 0.1 1.9e-85 284.6 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 OAJ23123.1 - 5e-28 96.6 0.0 1.1e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 OAJ23123.1 - 2.2e-22 79.1 3.9 4.3e-17 61.6 0.0 2.4 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 OAJ23123.1 - 1.6e-06 27.9 6.8 7.7e-06 25.7 4.7 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ23123.1 - 2.4e-06 27.5 0.0 5.3e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 TFIIA PF03153.8 OAJ23123.1 - 1.5 8.6 9.0 2.3 8.0 6.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PGM_PMM_I PF02878.11 OAJ23124.1 - 2.2e-36 124.4 0.1 3.3e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 OAJ23124.1 - 1.8e-27 95.5 0.0 4.6e-27 94.3 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 OAJ23124.1 - 1.5e-14 54.1 0.0 4.4e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 OAJ23124.1 - 2e-09 37.3 0.0 7.1e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain MPC PF03650.8 OAJ23128.1 - 2.2e-37 127.6 0.4 2.4e-37 127.5 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) ILVD_EDD PF00920.16 OAJ23129.1 - 8.5e-196 651.3 0.1 1e-195 651.1 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Abhydrolase_6 PF12697.2 OAJ23130.1 - 3.3e-13 50.0 0.2 4.6e-13 49.5 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ23130.1 - 3.3e-06 26.8 0.2 5.9e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ23130.1 - 3.3e-05 23.6 0.1 5.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_L16 PF00252.13 OAJ23132.1 - 7.5e-18 64.5 0.5 9.7e-16 57.7 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein L16p/L10e TFIIF_beta PF02270.10 OAJ23134.1 - 1.6e-11 44.5 0.0 2.2e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Serglycin PF04360.7 OAJ23134.1 - 0.074 12.7 4.1 0.15 11.7 0.6 2.2 2 0 0 2 2 2 0 Serglycin SNARE PF05739.14 OAJ23135.1 - 0.0078 15.8 0.0 0.0095 15.6 0.0 1.1 1 0 0 1 1 1 1 SNARE domain V-SNARE_C PF12352.3 OAJ23135.1 - 0.09 12.8 0.3 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus RNA_pol_I_A49 PF06870.7 OAJ23136.1 - 6e-65 219.2 0.0 9.1e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor IF2_N PF04760.10 OAJ23136.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Chitin_synth_1 PF01644.12 OAJ23137.1 - 4.5e-33 114.3 0.0 9e-29 100.3 0.0 2.5 2 1 0 2 2 2 2 Chitin synthase Chitin_synth_2 PF03142.10 OAJ23137.1 - 1.4e-11 43.4 0.0 2.7e-06 26.0 0.0 3.0 2 1 1 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.6 OAJ23137.1 - 3.6e-10 39.3 0.8 6.6e-10 38.5 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal DLIC PF05783.6 OAJ23138.1 - 1.3e-40 139.5 11.4 8.9e-27 93.8 0.0 6.7 5 2 1 6 6 6 4 Dynein light intermediate chain (DLIC) MCM PF00493.18 OAJ23138.1 - 6.4e-05 21.9 0.0 0.00013 20.9 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family AAA_16 PF13191.1 OAJ23138.1 - 0.0042 17.0 0.4 0.027 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.22 OAJ23138.1 - 0.0059 16.0 0.0 2.7 7.3 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 OAJ23138.1 - 0.0073 15.7 0.1 1.6 8.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 OAJ23138.1 - 0.088 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 OAJ23138.1 - 0.096 13.1 0.2 1.7 9.1 0.0 2.7 2 1 1 3 3 3 0 Miro-like protein AAA_28 PF13521.1 OAJ23138.1 - 0.14 12.1 0.9 0.23 11.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain PPR_2 PF13041.1 OAJ23139.1 - 1.9e-27 94.9 0.0 1.8e-07 31.0 0.0 9.3 7 2 3 10 10 10 4 PPR repeat family PPR_3 PF13812.1 OAJ23139.1 - 7.3e-25 85.1 28.3 0.00034 20.6 0.0 15.7 17 0 0 17 17 17 6 Pentatricopeptide repeat domain PPR PF01535.15 OAJ23139.1 - 7.3e-21 72.6 11.7 0.014 15.3 0.0 11.7 14 0 0 14 14 14 6 PPR repeat PPR_1 PF12854.2 OAJ23139.1 - 1.4e-10 40.4 0.0 8.2 5.9 0.0 8.9 9 0 0 9 9 9 3 PPR repeat Ferritin-like PF12902.2 OAJ23139.1 - 0.025 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Ferritin-like TPR_16 PF13432.1 OAJ23139.1 - 0.03 15.0 0.0 0.03 15.0 0.0 6.0 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ23139.1 - 0.053 13.8 4.5 0.48 10.8 0.0 4.7 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ23139.1 - 0.12 13.0 0.1 0.12 13.0 0.1 8.3 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ23139.1 - 0.22 11.5 9.5 1.6 8.7 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat YfhE PF14152.1 OAJ23140.1 - 0.12 12.2 0.2 0.23 11.3 0.2 1.4 1 0 0 1 1 1 0 YfhE-like protein Pex14_N PF04695.8 OAJ23140.1 - 2.6 8.0 7.3 0.35 10.9 0.5 2.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Phage_integrase PF00589.17 OAJ23141.1 - 0.00012 21.8 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family tRNA-synt_1 PF00133.17 OAJ23142.1 - 1.6e-209 696.8 0.0 1.4e-208 693.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 OAJ23142.1 - 4.1e-36 124.0 0.2 8.4e-36 123.0 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 OAJ23142.1 - 6.4e-19 67.8 0.3 1.2e-09 37.3 0.1 4.9 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 OAJ23142.1 - 7.5e-08 31.8 5.8 4.7e-06 26.0 0.0 2.9 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 OAJ23142.1 - 0.0008 18.6 0.0 0.49 9.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 OAJ23142.1 - 0.0016 17.3 0.0 0.034 12.9 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1c PF00749.16 OAJ23142.1 - 0.027 13.1 0.5 2.4 6.7 0.0 3.5 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain ATG11 PF10377.4 OAJ23142.1 - 0.14 12.0 1.7 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Autophagy-related protein 11 Sugar_tr PF00083.19 OAJ23143.1 - 4.7e-121 404.5 30.7 5.4e-121 404.3 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ23143.1 - 3.5e-20 72.0 46.5 9.6e-18 64.0 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DEADboxA PF12343.3 OAJ23143.1 - 0.11 12.7 0.2 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Cold shock protein DEAD box A TFIID-31kDa PF02291.10 OAJ23144.1 - 7e-39 132.5 0.0 1e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 OAJ23144.1 - 0.0039 16.9 0.0 0.0075 15.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated MAD PF05557.8 OAJ23145.1 - 7.4e-34 116.9 45.9 2.6e-25 88.6 9.5 3.0 2 1 0 2 2 2 2 Mitotic checkpoint protein ATG16 PF08614.6 OAJ23145.1 - 0.0029 17.4 23.4 0.0029 17.4 16.2 5.5 2 2 1 3 3 3 1 Autophagy protein 16 (ATG16) COG5 PF10392.4 OAJ23145.1 - 0.0039 17.1 5.1 0.0039 17.1 3.5 3.2 3 0 0 3 3 3 1 Golgi transport complex subunit 5 KIAA1430 PF13879.1 OAJ23145.1 - 0.029 14.7 0.0 0.029 14.7 0.0 2.9 2 1 1 3 3 3 0 KIAA1430 homologue Pox_G5 PF04599.7 OAJ23145.1 - 0.61 8.7 2.0 1.6 7.3 1.4 1.6 1 0 0 1 1 1 0 Poxvirus G5 protein Reo_sigmaC PF04582.7 OAJ23145.1 - 0.81 8.8 17.6 0.3 10.2 1.1 4.6 4 1 1 5 5 5 0 Reovirus sigma C capsid protein Orthopox_A5L PF06193.6 OAJ23145.1 - 1 9.3 14.0 15 5.4 5.9 3.5 2 2 0 2 2 2 0 Orthopoxvirus A5L protein-like DUF3037 PF11236.3 OAJ23145.1 - 1.6 8.8 7.4 0.51 10.4 0.6 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3037) HALZ PF02183.13 OAJ23145.1 - 9.5 6.0 34.4 0.49 10.1 1.5 6.5 7 0 0 7 7 7 0 Homeobox associated leucine zipper RNA_pol_Rpb4 PF03874.11 OAJ23149.1 - 4.6e-14 52.4 0.1 6.8e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Cep57_CLD_2 PF14197.1 OAJ23149.1 - 1.4 8.9 4.5 8.2 6.4 1.8 2.6 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 NAD_binding_5 PF07994.7 OAJ23150.1 - 4.9e-108 361.1 0.0 6.4e-108 360.7 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 OAJ23150.1 - 2.1e-42 143.4 0.1 3.6e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase WD40 PF00400.27 OAJ23152.1 - 6.7e-35 117.7 19.4 1e-10 41.0 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF4613 PF15390.1 OAJ23152.1 - 0.011 13.9 0.3 0.015 13.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) eIF2A PF08662.6 OAJ23152.1 - 0.13 11.9 0.2 0.46 10.1 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A RXT2_N PF08595.6 OAJ23152.1 - 1 9.1 3.7 1.6 8.4 2.5 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Fungal_trans PF04082.13 OAJ23153.1 - 1.3e-15 56.9 0.0 1.9e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ23153.1 - 2e-06 27.6 9.7 3.5e-06 26.8 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adaptin_binding PF10199.4 OAJ23154.1 - 0.006 16.8 23.0 0.062 13.5 11.9 3.8 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Velvet PF11754.3 OAJ23155.1 - 1.8e-57 194.2 0.0 3e-36 124.9 0.0 2.1 2 0 0 2 2 2 2 Velvet factor Lamp PF01299.12 OAJ23156.1 - 0.41 9.7 1.6 0.46 9.5 1.1 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) MRP-S26 PF14943.1 OAJ23157.1 - 0.33 10.4 7.4 0.7 9.4 3.4 2.1 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 PX PF00787.19 OAJ23158.1 - 3.6e-21 75.0 0.0 4.5e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 PX domain Neisseria_TspB PF05616.8 OAJ23158.1 - 3.8 5.7 9.1 4.9 5.3 6.3 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein UPF0020 PF01170.13 OAJ23159.1 - 8e-14 51.5 0.0 2.8e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 OAJ23159.1 - 1.5e-12 47.5 0.0 7.9e-12 45.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ23159.1 - 0.0021 17.6 0.0 0.052 13.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ23159.1 - 0.0088 16.5 0.0 0.024 15.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ23159.1 - 0.019 15.2 0.0 0.069 13.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ23159.1 - 0.13 11.3 0.0 0.87 8.6 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family zf-CCCH PF00642.19 OAJ23160.1 - 0.00065 19.3 1.9 0.0012 18.5 1.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 OAJ23160.1 - 0.39 10.7 3.2 1.2 9.2 2.2 1.9 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type APS_kinase PF01583.15 OAJ23161.1 - 1.5e-70 235.8 0.0 1.9e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 OAJ23161.1 - 1.4e-07 31.4 0.0 2e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ23161.1 - 4.9e-06 27.3 0.0 8.4e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ23161.1 - 4.1e-05 23.8 0.0 0.00011 22.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 OAJ23161.1 - 0.00061 19.0 0.0 0.00096 18.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 OAJ23161.1 - 0.0027 17.2 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Thymidylate_kin PF02223.12 OAJ23161.1 - 0.054 12.8 0.0 5.6 6.2 0.0 2.3 1 1 1 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.7 OAJ23161.1 - 0.056 12.5 0.0 0.28 10.2 0.0 1.9 1 1 0 2 2 2 0 Zeta toxin Arf PF00025.16 OAJ23161.1 - 0.058 12.6 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_16 PF13191.1 OAJ23161.1 - 0.096 12.6 0.1 0.21 11.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 OAJ23161.1 - 0.11 12.2 0.0 0.22 11.1 0.0 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 OAJ23161.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Ribosomal_L1 PF00687.16 OAJ23162.1 - 1.2e-48 165.3 0.6 1.5e-48 165.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Borealin PF10512.4 OAJ23162.1 - 0.12 12.3 0.1 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 Ribosomal_L10 PF00466.15 OAJ23163.1 - 5.3e-16 58.3 0.0 7.6e-15 54.6 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L10 DUF2457 PF10446.4 OAJ23163.1 - 0.016 13.9 4.2 0.024 13.3 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 OAJ23163.1 - 0.12 11.8 5.4 0.21 11.1 3.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 OAJ23163.1 - 0.42 9.8 2.7 0.59 9.3 1.9 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 OAJ23163.1 - 0.73 10.1 9.5 1.4 9.2 6.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NUC153 PF08159.7 OAJ23165.1 - 6.2e-11 41.6 0.2 1.1e-10 40.9 0.2 1.4 1 0 0 1 1 1 1 NUC153 domain Nop14 PF04147.7 OAJ23165.1 - 0.066 11.1 20.7 0.094 10.6 14.4 1.1 1 0 0 1 1 1 0 Nop14-like family DASH_Spc34 PF08657.5 OAJ23166.1 - 2.3e-08 34.0 0.4 1.3e-05 25.0 0.1 2.4 1 1 0 2 2 2 2 DASH complex subunit Spc34 DivIC PF04977.10 OAJ23166.1 - 3.6 7.1 9.9 13 5.4 0.4 3.2 3 0 0 3 3 3 0 Septum formation initiator Pmp3 PF01679.12 OAJ23167.1 - 4.6e-20 71.0 5.2 7.7e-20 70.3 3.6 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Peptidase_M17 PF00883.16 OAJ23168.1 - 1.4e-110 369.0 0.1 1.8e-110 368.6 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 OAJ23168.1 - 1.1e-07 31.6 0.1 2.6e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain DUF2317 PF10079.4 OAJ23175.1 - 0.0022 16.6 1.0 0.0031 16.1 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2317) Sec62 PF03839.11 OAJ23175.1 - 0.0025 17.2 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 GAGA_bind PF06217.7 OAJ23175.1 - 0.095 12.6 3.6 0.12 12.3 2.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family TATR PF03430.8 OAJ23175.1 - 0.21 10.1 1.8 0.25 9.9 1.3 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF4337 PF14235.1 OAJ23175.1 - 0.29 10.9 3.5 0.59 9.9 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RR_TM4-6 PF06459.7 OAJ23175.1 - 0.94 9.3 6.9 1.2 9.0 4.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CAF-1_p150 PF11600.3 OAJ23175.1 - 2.2 7.6 25.8 3.2 7.0 17.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Phage_min_cap2 PF06152.6 OAJ23175.1 - 3.6 6.4 10.5 4.7 6.0 7.3 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 NARP1 PF12569.3 OAJ23175.1 - 4 6.0 10.4 5 5.7 7.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S8 PF00082.17 OAJ23176.1 - 1.9e-25 89.5 2.9 1.9e-25 89.5 2.0 1.9 2 0 0 2 2 2 1 Subtilase family DUF1034 PF06280.7 OAJ23176.1 - 9.9e-07 29.1 0.1 2.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 OAJ23176.1 - 1.8e-06 27.5 0.1 6.2e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 PA domain MFS_1 PF07690.11 OAJ23177.1 - 1.8e-26 92.7 63.6 3.7e-21 75.2 22.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ23177.1 - 2.3e-05 23.1 38.4 0.00065 18.3 8.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Sigma70_ner PF04546.8 OAJ23178.1 - 2.3 7.7 12.1 6 6.4 0.2 3.5 3 0 0 3 3 3 0 Sigma-70, non-essential region SNO PF01174.14 OAJ23179.1 - 1.6e-50 171.3 0.0 1.2e-39 135.9 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 OAJ23179.1 - 2.6e-07 30.3 0.1 3.8e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 OAJ23179.1 - 0.00063 19.2 0.2 0.00096 18.6 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.12 OAJ23179.1 - 0.005 16.5 0.0 0.0072 16.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 adh_short PF00106.20 OAJ23180.1 - 2.9e-05 24.0 0.0 6.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase CMAS PF02353.15 OAJ23181.1 - 7.6e-56 189.1 0.0 1.8e-51 174.8 0.0 2.9 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 OAJ23181.1 - 6.3e-11 42.8 0.0 1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ23181.1 - 2e-09 37.3 0.0 5.4e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ23181.1 - 5.1e-08 33.2 0.0 1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ23181.1 - 1.7e-07 30.9 0.0 2.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ23181.1 - 2.1e-06 27.7 0.1 4.7e-06 26.6 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ23181.1 - 8e-05 23.0 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ23181.1 - 0.0002 21.6 0.0 0.00039 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 OAJ23181.1 - 0.0007 19.2 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_24 PF13578.1 OAJ23181.1 - 0.0056 17.5 0.0 0.013 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 OAJ23181.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.9 OAJ23181.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 OAJ23181.1 - 0.044 13.2 0.0 0.13 11.7 0.0 1.6 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.5 OAJ23181.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_3 PF01596.12 OAJ23181.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DUF3184 PF11380.3 OAJ23182.1 - 5.2e-20 70.9 9.0 5e-10 37.9 0.2 4.0 2 1 2 4 4 4 4 Protein of unknown function (DUF3184) DUF4028 PF13220.1 OAJ23183.1 - 0.021 14.4 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) COesterase PF00135.23 OAJ23184.1 - 1.3e-91 307.9 0.0 1.8e-91 307.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ23184.1 - 5e-06 26.2 0.3 0.0079 15.7 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Sulfatase PF00884.18 OAJ23185.1 - 1.4e-58 198.5 0.0 2e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 OAJ23185.1 - 0.0015 18.7 0.1 0.17 12.1 0.0 2.7 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 OAJ23185.1 - 0.0039 16.5 0.0 0.0081 15.5 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 OAJ23185.1 - 0.008 14.6 0.0 0.011 14.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 OAJ23185.1 - 0.11 11.8 0.0 11 5.3 0.0 2.1 2 0 0 2 2 2 0 Metalloenzyme superfamily Metallophos PF00149.23 OAJ23186.1 - 1.6e-05 24.4 0.0 3.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAJ23186.1 - 0.00047 20.0 0.0 0.0028 17.5 0.0 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain ABC_membrane_2 PF06472.10 OAJ23187.1 - 2.4e-98 328.7 5.4 3.3e-98 328.2 3.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 OAJ23187.1 - 1.4e-17 64.2 0.0 3e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 OAJ23187.1 - 0.0017 19.1 0.0 0.0049 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAJ23187.1 - 0.0028 16.7 0.0 0.0065 15.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 OAJ23187.1 - 0.0071 15.5 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 OAJ23187.1 - 0.013 15.5 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 OAJ23187.1 - 0.019 15.1 0.1 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 OAJ23187.1 - 0.019 14.7 0.1 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_21 PF13304.1 OAJ23187.1 - 0.033 14.1 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 OAJ23187.1 - 0.034 13.6 0.0 0.14 11.7 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 OAJ23187.1 - 0.046 14.0 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAJ23187.1 - 0.09 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 OAJ23187.1 - 0.095 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 OAJ23187.1 - 0.099 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ23187.1 - 0.12 12.1 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 OAJ23187.1 - 0.14 12.1 0.0 0.43 10.6 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF3584 PF12128.3 OAJ23187.1 - 0.25 8.6 0.0 0.4 7.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rad60-SLD PF11976.3 OAJ23188.1 - 4.8e-12 45.4 0.4 4.8e-12 45.4 0.3 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 OAJ23188.1 - 0.00064 19.0 0.1 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DnaJ PF00226.26 OAJ23189.1 - 1.8e-08 33.9 0.1 2.3e-07 30.4 0.1 2.7 1 1 0 1 1 1 1 DnaJ domain MIP-T3 PF10243.4 OAJ23189.1 - 0.066 11.6 46.2 0.095 11.1 32.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Gly-rich_Ago1 PF12764.2 OAJ23190.1 - 0.092 13.3 0.3 0.13 12.9 0.2 1.2 1 0 0 1 1 1 0 Glycine-rich region of argonaut DnaJ PF00226.26 OAJ23191.1 - 6.1e-12 45.0 0.0 6.1e-12 45.0 0.0 2.1 2 1 0 2 2 1 1 DnaJ domain Peptidase_C37 PF05416.7 OAJ23191.1 - 0.00048 18.5 8.0 0.00058 18.2 5.5 1.1 1 0 0 1 1 1 1 Southampton virus-type processing peptidase SprA-related PF12118.3 OAJ23191.1 - 0.008 15.5 21.0 0.011 15.1 14.6 1.3 1 0 0 1 1 1 1 SprA-related family DUF1510 PF07423.6 OAJ23191.1 - 0.036 13.4 13.7 0.056 12.8 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SAGA-Tad1 PF12767.2 OAJ23191.1 - 0.056 13.1 13.3 0.066 12.8 9.2 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit RNase_H2-Ydr279 PF09468.5 OAJ23191.1 - 0.062 12.4 3.9 0.075 12.2 2.7 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) TFIIA PF03153.8 OAJ23191.1 - 0.14 11.9 20.8 0.17 11.7 14.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gag_spuma PF03276.9 OAJ23191.1 - 0.19 10.0 24.3 0.27 9.5 16.9 1.2 1 0 0 1 1 1 0 Spumavirus gag protein RR_TM4-6 PF06459.7 OAJ23191.1 - 0.42 10.4 15.7 0.56 10.0 10.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 OAJ23191.1 - 0.44 8.1 14.0 0.49 8.0 9.7 1.1 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 OAJ23191.1 - 0.53 10.0 11.1 0.71 9.6 7.7 1.3 1 0 0 1 1 1 0 DDHD domain DHHW PF14286.1 OAJ23191.1 - 0.78 8.9 7.5 0.92 8.7 5.2 1.1 1 0 0 1 1 1 0 DHHW protein FAM60A PF15396.1 OAJ23191.1 - 0.94 9.1 13.5 1.3 8.7 9.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Asp-B-Hydro_N PF05279.6 OAJ23191.1 - 1.1 9.0 15.5 1.4 8.7 10.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Herpes_DNAp_acc PF04929.7 OAJ23191.1 - 1.2 8.0 8.7 1.2 8.0 6.0 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PAT1 PF09770.4 OAJ23191.1 - 1.4 7.0 30.7 1.6 6.8 21.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.17 OAJ23191.1 - 1.8 7.5 4.4 2.3 7.1 3.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3260 PF11658.3 OAJ23191.1 - 2.2 6.3 7.5 3.3 5.7 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) RNA_pol_Rpb1_5 PF04998.12 OAJ23191.1 - 2.2 7.4 7.2 3.2 6.9 5.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF913 PF06025.7 OAJ23191.1 - 3 6.4 7.0 4.2 6.0 4.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.11 OAJ23191.1 - 3.4 7.4 11.0 4.4 7.1 7.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med15 PF09606.5 OAJ23191.1 - 3.9 5.5 34.0 4.6 5.3 23.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.12 OAJ23191.1 - 6.2 5.5 7.2 7.3 5.2 5.0 1.3 1 0 0 1 1 1 0 Presenilin DUF3492 PF11997.3 OAJ23191.1 - 7.7 5.9 9.1 11 5.4 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) DDRGK PF09756.4 OAJ23191.1 - 8.1 5.8 32.4 14 5.0 22.5 1.4 1 0 0 1 1 1 0 DDRGK domain CAF-1_p150 PF11600.3 OAJ23191.1 - 8.3 5.7 38.5 14 4.9 26.7 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Spore_coat_CotO PF14153.1 OAJ23191.1 - 8.8 5.7 24.6 12 5.2 17.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO PI3Ka PF00613.15 OAJ23194.1 - 7.7e-53 178.4 0.0 1.2e-52 177.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 OAJ23194.1 - 1.6e-43 148.8 0.0 3.2e-42 144.6 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 OAJ23194.1 - 5.7e-34 116.9 0.0 9.1e-34 116.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.25 OAJ23194.1 - 0.0032 17.2 0.0 0.0075 16.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Transketolase_N PF00456.16 OAJ23196.1 - 2.3e-17 62.8 2.7 1.3e-15 57.0 1.8 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 OAJ23196.1 - 9.9e-11 41.6 0.0 3.4e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 OAJ23196.1 - 3.4e-05 23.4 0.0 8.2e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 OAJ23196.1 - 0.012 14.3 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 OAJ23196.1 - 0.1 12.1 0.2 0.46 10.0 0.0 2.1 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Caudo_TAP PF02413.12 OAJ23197.1 - 1.2 9.2 7.3 3.1 7.9 5.0 1.6 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein RasGEF PF00617.14 OAJ23198.1 - 1e-41 142.7 0.0 2.1e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 OAJ23198.1 - 8.7e-19 67.5 0.0 1.7e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 OAJ23198.1 - 2.9e-14 52.3 0.1 6.1e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ23198.1 - 3.6e-14 51.9 0.1 8.4e-14 50.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ23198.1 - 4.6e-13 48.3 0.0 8.1e-13 47.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain RhoGAP PF00620.22 OAJ23198.1 - 0.27 10.8 0.0 8.1 6.0 0.0 2.3 2 0 0 2 2 2 0 RhoGAP domain Pkinase PF00069.20 OAJ23201.1 - 1.5e-21 76.7 0.0 3.3e-21 75.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ23201.1 - 1.6e-05 24.1 0.0 5.4e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ23201.1 - 0.0084 15.0 0.0 0.016 14.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ23201.1 - 0.05 12.6 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ23201.1 - 0.051 13.2 0.2 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family ACBP PF00887.14 OAJ23202.1 - 2.7e-26 91.0 0.0 4.1e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Nucleoplasmin PF03066.10 OAJ23202.1 - 0.19 11.2 7.4 0.36 10.3 5.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin Menin PF05053.8 OAJ23202.1 - 0.23 9.5 0.7 0.34 9.0 0.5 1.1 1 0 0 1 1 1 0 Menin Myc_N PF01056.13 OAJ23202.1 - 0.89 8.6 5.5 1.4 7.9 3.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 OAJ23202.1 - 0.92 7.9 8.3 1.3 7.4 5.8 1.0 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 OAJ23202.1 - 2.1 7.9 7.4 3.2 7.4 5.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.8 OAJ23202.1 - 5.6 6.5 7.1 10 5.6 4.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 OAJ23202.1 - 6.5 5.9 5.7 9.8 5.3 4.0 1.2 1 0 0 1 1 1 0 NOA36 protein ABC_tran PF00005.22 OAJ23203.1 - 1.2e-47 161.7 0.0 2.3e-26 92.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 OAJ23203.1 - 1.3e-45 155.9 17.9 2.6e-19 69.7 2.0 4.1 3 1 1 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.14 OAJ23203.1 - 1.2e-11 44.2 0.3 2.7e-05 23.5 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 OAJ23203.1 - 2.9e-06 26.8 0.0 0.027 13.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 OAJ23203.1 - 4e-06 26.4 0.0 0.042 13.3 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_29 PF13555.1 OAJ23203.1 - 1.1e-05 24.9 0.8 0.1 12.1 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 OAJ23203.1 - 2.1e-05 24.4 2.0 0.036 13.8 0.2 2.6 3 0 0 3 3 2 2 Dynamin family Miro PF08477.8 OAJ23203.1 - 4.1e-05 24.0 0.0 0.16 12.4 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_21 PF13304.1 OAJ23203.1 - 5.5e-05 23.2 4.5 3.8 7.3 0.0 4.5 5 0 0 5 5 4 1 AAA domain DUF258 PF03193.11 OAJ23203.1 - 8.4e-05 21.8 0.1 0.14 11.3 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 OAJ23203.1 - 0.00023 21.0 0.6 0.36 10.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 OAJ23203.1 - 0.0003 21.1 0.1 0.09 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 OAJ23203.1 - 0.00031 19.8 0.6 0.54 9.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.18 OAJ23203.1 - 0.00033 20.6 0.0 0.83 9.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 OAJ23203.1 - 0.0008 20.2 0.0 0.1 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 OAJ23203.1 - 0.00096 18.6 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 OAJ23203.1 - 0.0011 19.1 0.3 1.9 8.6 0.0 3.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 OAJ23203.1 - 0.0046 15.8 0.0 2.7 6.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein IstB_IS21 PF01695.12 OAJ23203.1 - 0.027 13.8 0.1 1.7 8.0 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF815 PF05673.8 OAJ23203.1 - 0.028 13.3 0.2 3.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 OAJ23203.1 - 0.048 13.6 4.8 1.7 8.6 0.3 3.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 OAJ23203.1 - 0.069 13.4 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 OAJ23203.1 - 0.1 12.4 2.3 12 5.7 0.1 2.8 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 OAJ23203.1 - 0.11 12.4 0.7 0.96 9.4 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 OAJ23203.1 - 0.18 11.4 0.2 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B KH_1 PF00013.24 OAJ23204.1 - 8.3e-40 134.2 13.1 5.1e-16 58.0 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 OAJ23204.1 - 1e-29 101.5 12.1 1.2e-10 40.7 1.7 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 OAJ23204.1 - 3e-10 39.5 6.9 0.0038 16.7 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 OAJ23204.1 - 1.4e-07 31.0 0.9 0.17 11.5 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 OAJ23204.1 - 0.031 14.0 5.1 1.4 8.7 0.1 3.1 3 0 0 3 3 3 0 NusA-like KH domain dUTPase PF00692.14 OAJ23204.1 - 0.041 13.3 1.3 0.26 10.7 0.1 2.6 3 0 0 3 3 3 0 dUTPase Complex1_LYR_1 PF13232.1 OAJ23205.1 - 1.2e-06 28.5 0.6 1.9e-06 27.9 0.3 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 OAJ23205.1 - 1.5e-05 24.6 0.7 2.4e-05 24.0 0.5 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 OAJ23205.1 - 0.074 13.5 0.9 0.11 12.9 0.6 1.3 1 0 0 1 1 1 0 Complex1_LYR-like TIMELESS PF04821.9 OAJ23206.1 - 7e-42 143.5 4.3 2.3e-41 141.8 0.0 3.2 2 1 0 2 2 2 1 Timeless protein DUF4106 PF13388.1 OAJ23207.1 - 0.58 9.0 4.5 0.7 8.7 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) adh_short PF00106.20 OAJ23214.1 - 4.7e-25 88.4 2.2 8.5e-24 84.3 1.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ23214.1 - 3.9e-20 72.6 0.3 2e-19 70.3 0.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ23214.1 - 5.5e-09 35.9 2.6 1.5e-08 34.5 0.4 2.3 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 OAJ23214.1 - 0.0003 20.3 1.0 0.0048 16.3 0.7 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 OAJ23214.1 - 0.0031 17.6 1.3 0.014 15.4 0.9 2.1 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 OAJ23214.1 - 0.0085 16.1 0.4 0.02 14.8 0.2 1.7 2 0 0 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 OAJ23214.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 OAJ23214.1 - 0.084 11.7 0.1 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YjeF_N PF03853.10 OAJ23214.1 - 0.088 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus RNase_P_Rpp14 PF01900.14 OAJ23214.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Rpp14/Pop5 family Robl_LC7 PF03259.12 OAJ23215.1 - 3.5e-06 26.4 0.0 6.5e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 Roadblock/LC7 domain Glyco_hydro_18 PF00704.23 OAJ23216.1 - 1.6e-58 198.7 2.4 2e-58 198.4 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 OHCU_decarbox PF09349.5 OAJ23217.1 - 7.5e-25 88.0 0.0 1.6e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 OHCU decarboxylase SCO1-SenC PF02630.9 OAJ23218.1 - 3.2e-53 179.9 0.0 4.5e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 OAJ23218.1 - 0.0097 15.5 0.0 0.027 14.1 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family HAD_2 PF13419.1 OAJ23219.1 - 3.8e-18 66.3 0.0 2.8e-17 63.5 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAJ23219.1 - 6.4e-06 26.7 0.0 1.7e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAJ23219.1 - 3.9e-05 23.2 0.0 6.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like SKN1 PF03935.10 OAJ23220.1 - 2.5e-153 510.8 0.1 3.9e-153 510.2 0.1 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DASH_Ask1 PF08655.5 OAJ23221.1 - 1.9e-28 98.0 0.0 3e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 zf-C3HC4_2 PF13923.1 OAJ23223.1 - 2.5e-11 43.3 9.6 2.5e-11 43.3 6.6 3.1 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ23223.1 - 2.3e-09 36.9 9.3 2.3e-09 36.9 6.4 3.0 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAJ23223.1 - 4.2e-08 32.7 6.6 4.2e-08 32.7 4.6 3.2 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ23223.1 - 8e-08 31.8 6.3 8e-08 31.8 4.4 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 OAJ23223.1 - 8.4e-08 31.7 9.0 8.4e-08 31.7 6.2 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAJ23223.1 - 1.3e-05 24.8 5.2 2.9e-05 23.6 3.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 OAJ23223.1 - 2.8e-05 23.7 2.3 2.8e-05 23.7 1.6 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 OAJ23223.1 - 0.00052 19.8 9.2 0.00052 19.8 6.3 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 OAJ23223.1 - 0.0006 19.8 3.6 0.002 18.1 2.5 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger U-box PF04564.10 OAJ23223.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 U-box domain Prok-RING_4 PF14447.1 OAJ23223.1 - 0.055 13.0 4.0 0.16 11.5 2.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-P11 PF03854.9 OAJ23223.1 - 2.9 7.4 11.1 0.97 8.9 4.4 2.6 2 1 1 3 3 3 0 P-11 zinc finger Ras PF00071.17 OAJ23224.1 - 3.7e-57 192.2 0.1 4.4e-57 191.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ23224.1 - 8.9e-19 68.1 0.0 1.9e-18 67.0 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 OAJ23224.1 - 3.9e-14 52.2 0.0 4.5e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ23224.1 - 9.4e-08 31.6 0.0 1.7e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ23224.1 - 2.6e-07 30.5 0.0 3.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 OAJ23224.1 - 7.1e-07 28.6 0.1 8.9e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 OAJ23224.1 - 0.00033 20.2 0.6 0.017 14.7 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 OAJ23224.1 - 0.0005 20.2 0.0 0.00097 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 OAJ23224.1 - 0.0012 18.0 0.1 0.0029 16.7 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 OAJ23224.1 - 0.0016 17.8 0.1 0.18 11.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 OAJ23224.1 - 0.0035 16.4 0.2 0.053 12.5 0.0 2.3 2 1 0 2 2 2 1 Septin AAA_16 PF13191.1 OAJ23224.1 - 0.0043 17.0 0.0 0.02 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 OAJ23224.1 - 0.0048 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 OAJ23224.1 - 0.0063 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase cobW PF02492.14 OAJ23224.1 - 0.0076 15.7 0.0 0.031 13.7 0.0 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 OAJ23224.1 - 0.01 15.2 0.1 0.018 14.5 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain SRPRB PF09439.5 OAJ23224.1 - 0.017 14.3 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 OAJ23224.1 - 0.017 14.8 0.0 0.06 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 OAJ23224.1 - 0.022 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 NTPase MobB PF03205.9 OAJ23224.1 - 0.033 13.9 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 OAJ23224.1 - 0.07 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 OAJ23224.1 - 0.097 11.9 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B MutS_V PF00488.16 OAJ23225.1 - 2.2e-61 207.2 0.0 3.5e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAJ23225.1 - 2.1e-10 40.7 0.5 2.1e-10 40.7 0.3 2.9 2 1 1 3 3 3 1 MutS domain III AAA_29 PF13555.1 OAJ23225.1 - 0.0085 15.6 0.0 0.025 14.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 OAJ23225.1 - 0.012 15.0 0.1 0.085 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 OAJ23225.1 - 0.082 12.8 0.0 0.31 10.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 OAJ23225.1 - 0.5 10.6 3.7 0.93 9.7 0.0 2.9 4 0 0 4 4 4 0 AAA domain FtsX PF02687.16 OAJ23227.1 - 0.017 14.8 0.8 0.036 13.8 0.6 1.5 1 0 0 1 1 1 0 FtsX-like permease family zf-CCHC PF00098.18 OAJ23228.1 - 1.6e-09 37.2 13.7 9e-05 22.2 1.3 2.7 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 OAJ23228.1 - 1.5e-07 30.9 0.3 2.8e-07 30.0 0.2 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 OAJ23228.1 - 1.1e-06 28.2 10.5 0.00017 21.2 2.4 2.4 1 1 1 2 2 2 2 Zinc knuckle DUF1897 PF09005.5 OAJ23228.1 - 4.2e-06 26.1 20.0 0.00011 21.6 2.7 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF1897) KH_3 PF13014.1 OAJ23228.1 - 0.00025 20.6 0.1 0.00057 19.4 0.1 1.7 1 0 0 1 1 1 1 KH domain DUF4609 PF15382.1 OAJ23228.1 - 0.16 11.6 0.4 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) zf-CCHC_4 PF14392.1 OAJ23228.1 - 0.17 11.5 9.3 1.1 9.0 0.8 2.3 2 0 0 2 2 2 0 Zinc knuckle Zn_clus PF00172.13 OAJ23229.1 - 1.2e-06 28.2 9.6 2.1e-06 27.5 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2781 PF10914.3 OAJ23230.1 - 1.9e-30 105.6 7.2 2.2e-30 105.4 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Asp PF00026.18 OAJ23231.1 - 8.6e-16 58.0 0.0 2.7e-12 46.5 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ23231.1 - 0.016 15.2 0.1 0.078 12.9 0.0 2.3 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal BING4CT PF08149.6 OAJ23236.1 - 2.9e-34 116.4 0.0 6.6e-33 112.0 0.0 3.0 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.27 OAJ23236.1 - 3.6e-07 29.8 0.0 3.9e-05 23.3 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 OAJ23236.1 - 0.00041 19.2 0.0 0.0006 18.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region Arm PF00514.18 OAJ23237.1 - 3.9e-95 308.8 13.2 7.1e-14 51.0 0.0 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 OAJ23237.1 - 1.8e-24 85.8 0.9 3.2e-08 33.7 0.0 6.6 1 1 5 6 6 6 5 HEAT repeats HEAT_EZ PF13513.1 OAJ23237.1 - 1.2e-23 82.8 3.9 6e-09 36.1 0.0 6.5 5 1 2 7 7 7 4 HEAT-like repeat HEAT PF02985.17 OAJ23237.1 - 1.3e-18 65.3 3.8 7.6e-05 22.4 0.0 7.7 7 0 0 7 7 7 3 HEAT repeat IBB PF01749.15 OAJ23237.1 - 3.6e-18 65.5 5.1 8.2e-18 64.3 3.5 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_PBS PF03130.11 OAJ23237.1 - 8.2e-05 22.7 2.7 0.051 14.0 0.0 5.6 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Arm_2 PF04826.8 OAJ23237.1 - 0.00014 21.1 0.0 0.62 9.1 0.0 3.9 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 OAJ23237.1 - 0.00055 18.3 0.0 0.0076 14.6 0.0 2.4 1 1 0 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 OAJ23237.1 - 0.0086 15.9 0.2 3.3 7.6 0.0 4.2 3 3 1 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 OAJ23237.1 - 0.012 13.8 0.0 0.11 10.7 0.0 2.2 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit Vps35 PF03635.12 OAJ23237.1 - 0.17 9.9 0.0 0.34 9.0 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 Eclosion PF04736.7 OAJ23238.1 - 0.066 12.6 5.2 0.11 11.9 3.6 1.3 1 0 0 1 1 1 0 Eclosion hormone ABC_tran PF00005.22 OAJ23239.1 - 4.3e-47 159.8 0.2 4.2e-23 82.1 0.0 2.9 4 0 0 4 4 2 2 ABC transporter AAA_21 PF13304.1 OAJ23239.1 - 6.2e-21 75.6 1.7 0.00012 22.2 0.0 4.3 3 1 1 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 OAJ23239.1 - 7.5e-20 70.5 4.4 7.5e-20 70.5 3.0 2.2 2 0 0 2 2 1 1 ABC transporter AAA_23 PF13476.1 OAJ23239.1 - 7e-10 39.5 5.7 0.0015 18.8 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 OAJ23239.1 - 6e-09 35.3 0.2 0.0036 16.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 OAJ23239.1 - 1.2e-08 34.5 2.2 0.27 10.4 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 OAJ23239.1 - 1.2e-06 28.6 0.0 0.015 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 OAJ23239.1 - 4e-06 27.6 0.0 0.2 12.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 OAJ23239.1 - 4.4e-06 27.1 0.0 0.18 12.2 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 OAJ23239.1 - 3.3e-05 24.0 0.2 0.046 13.8 0.0 3.5 3 1 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 OAJ23239.1 - 3.4e-05 23.7 0.2 0.035 14.0 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 OAJ23239.1 - 8e-05 22.5 2.6 0.84 9.4 0.0 4.1 4 1 0 4 4 4 2 Dynamin family AAA_28 PF13521.1 OAJ23239.1 - 8.7e-05 22.5 0.0 0.33 10.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 OAJ23239.1 - 0.00017 20.8 11.3 0.073 12.1 0.0 4.7 4 2 0 4 4 4 1 AAA ATPase domain DUF258 PF03193.11 OAJ23239.1 - 0.00019 20.6 0.0 0.05 12.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 OAJ23239.1 - 0.00032 20.5 0.0 0.28 11.1 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 OAJ23239.1 - 0.00034 20.3 0.5 0.14 11.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 OAJ23239.1 - 0.00057 20.2 1.4 0.64 10.3 0.0 3.2 4 0 0 4 4 3 1 AAA domain T2SE PF00437.15 OAJ23239.1 - 0.001 18.0 0.0 0.32 9.8 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.1 OAJ23239.1 - 0.0011 18.8 0.0 1.5 8.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 OAJ23239.1 - 0.0015 18.2 3.5 1.1 8.9 0.1 3.5 3 1 1 4 4 3 2 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 OAJ23239.1 - 0.0015 18.0 0.1 2.3 7.6 0.0 2.8 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_25 PF13481.1 OAJ23239.1 - 0.0022 17.4 0.0 0.96 8.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.17 OAJ23239.1 - 0.0027 16.6 0.1 0.68 8.7 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain ArgK PF03308.11 OAJ23239.1 - 0.003 16.3 0.0 0.44 9.2 0.0 2.8 3 0 0 3 3 3 1 ArgK protein AAA_10 PF12846.2 OAJ23239.1 - 0.0052 16.2 0.2 4.6 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 OAJ23239.1 - 0.0055 16.6 0.2 12 5.7 0.1 4.0 3 1 0 3 3 3 0 AAA domain cobW PF02492.14 OAJ23239.1 - 0.0055 16.1 1.0 0.81 9.1 0.0 2.8 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 OAJ23239.1 - 0.0059 16.7 0.4 1.3 9.2 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 OAJ23239.1 - 0.012 15.8 1.1 7.5 6.7 0.1 3.1 3 0 0 3 3 3 0 RNA helicase FeoB_N PF02421.13 OAJ23239.1 - 0.014 14.6 0.0 0.47 9.7 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B NTPase_1 PF03266.10 OAJ23239.1 - 0.023 14.3 3.2 12 5.5 0.1 3.6 4 0 0 4 4 4 0 NTPase AAA_5 PF07728.9 OAJ23239.1 - 0.036 13.7 0.9 8.3 6.1 0.1 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 OAJ23239.1 - 0.041 13.4 5.6 1.7 8.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 OAJ23239.1 - 0.049 13.1 0.0 4.9 6.5 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.12 OAJ23239.1 - 0.14 11.9 5.6 3.7 7.3 0.0 3.7 4 1 1 5 5 4 0 Domain of unknown function DUF87 CAP PF00188.21 OAJ23240.1 - 1.1e-19 71.0 1.2 1.7e-19 70.5 0.9 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Med3 PF11593.3 OAJ23240.1 - 0.0041 16.4 13.2 0.0047 16.2 9.2 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Tyrosinase PF00264.15 OAJ23240.1 - 0.1 12.7 0.4 0.13 12.3 0.3 1.3 1 0 0 1 1 1 0 Common central domain of tyrosinase TFIIA PF03153.8 OAJ23240.1 - 1.8 8.3 3.5 2.5 7.9 2.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Formyl_trans_N PF00551.14 OAJ23241.1 - 1.1e-24 86.9 0.0 3.1e-24 85.5 0.0 1.8 1 0 0 1 1 1 1 Formyl transferase DnaJ PF00226.26 OAJ23241.1 - 3.6e-18 65.0 0.2 6.3e-18 64.2 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DHH PF01368.15 OAJ23241.1 - 3.7e-05 23.4 0.0 0.00012 21.7 0.0 1.8 1 1 0 1 1 1 1 DHH family MAGE PF01454.14 OAJ23243.1 - 5.9e-19 68.1 0.0 4.9e-15 55.4 0.0 2.7 3 0 0 3 3 3 2 MAGE family MRP-L27 PF09809.4 OAJ23244.1 - 1.4e-06 27.8 0.3 2.9e-05 23.6 0.2 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 MFS_1 PF07690.11 OAJ23246.1 - 7.3e-09 34.7 20.1 7.3e-09 34.7 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Baculo_PEP_C PF04513.7 OAJ23247.1 - 0.11 12.2 7.1 1.1 9.0 1.0 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG9 PF04109.11 OAJ23248.1 - 1.7e-150 501.0 0.0 2.1e-150 500.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Glyco_hydro_92 PF07971.7 OAJ23249.1 - 2.7e-104 349.5 0.0 4.9e-104 348.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_17 PF00332.13 OAJ23250.1 - 3.6e-08 32.8 0.2 0.00039 19.5 0.1 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 DUF1517 PF07466.6 OAJ23250.1 - 0.64 8.9 3.2 1.1 8.2 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF3526 PF12040.3 OAJ23251.1 - 0.025 14.7 0.1 0.031 14.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) DDE_3 PF13358.1 OAJ23253.1 - 1.5e-20 73.4 0.0 2.4e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 OAJ23253.1 - 3.9e-09 36.4 3.2 3.9e-09 36.4 2.2 3.2 4 0 0 4 4 4 1 Transposase HTH_Tnp_ISL3 PF13542.1 OAJ23253.1 - 4.1e-08 32.2 2.5 3.4e-05 22.9 0.0 3.7 4 0 0 4 4 4 2 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.1 OAJ23253.1 - 1.8e-06 27.4 0.6 7e-06 25.5 0.0 2.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.1 OAJ23253.1 - 6.8e-06 25.5 0.0 1.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 OAJ23253.1 - 0.00011 22.3 0.4 0.044 14.0 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain CENP-B_N PF04218.8 OAJ23253.1 - 0.00029 20.1 0.0 0.00067 19.0 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain GerE PF00196.14 OAJ23253.1 - 0.00065 18.9 0.1 0.0025 17.0 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_28 PF13518.1 OAJ23253.1 - 0.0023 17.9 0.0 0.0082 16.1 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain DUF2857 PF11198.3 OAJ23253.1 - 0.015 14.8 0.1 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) Sigma70_r4_2 PF08281.7 OAJ23253.1 - 0.032 13.6 0.3 0.18 11.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 rve PF00665.21 OAJ23253.1 - 0.045 13.8 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain HTH_7 PF02796.10 OAJ23253.1 - 0.091 12.6 0.5 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_3 PF01381.17 OAJ23253.1 - 0.092 12.6 0.3 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix LacI PF00356.16 OAJ23253.1 - 0.11 12.1 0.6 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_31 PF13560.1 OAJ23253.1 - 0.32 11.2 2.2 0.49 10.6 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain NAD_binding_10 PF13460.1 OAJ23255.1 - 1.2e-09 38.3 0.0 1.6e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAJ23255.1 - 2e-05 24.1 0.0 2.5e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAJ23255.1 - 0.0054 15.4 0.0 0.0062 15.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 OAJ23255.1 - 0.011 15.6 0.0 0.033 14.1 0.0 1.8 1 1 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 OAJ23255.1 - 0.054 12.3 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4177 PF13783.1 OAJ23255.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) NmrA PF05368.8 OAJ23255.1 - 0.15 11.2 0.5 0.2 10.8 0.4 1.1 1 0 0 1 1 1 0 NmrA-like family Utp14 PF04615.8 OAJ23256.1 - 0.15 10.1 67.0 0.2 9.7 11.1 2.2 2 0 0 2 2 2 0 Utp14 protein PAT1 PF09770.4 OAJ23256.1 - 4 5.5 139.5 0.85 7.7 38.6 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 OAJ23256.1 - 4.8 5.3 46.1 2.9 6.0 8.5 2.2 2 0 0 2 2 2 0 Transmembrane protein Med15 PF09606.5 OAJ23256.1 - 6.8 4.7 173.5 0.41 8.8 63.4 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Nop14 PF04147.7 OAJ23258.1 - 3.5e-228 759.6 4.2 4.9e-228 759.1 2.9 1.2 1 0 0 1 1 1 1 Nop14-like family Dus PF01207.12 OAJ23259.1 - 2.4e-47 161.2 0.0 6.3e-32 110.6 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 OAJ23259.1 - 1.7e-07 30.7 5.6 0.00072 19.1 0.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PPR_2 PF13041.1 OAJ23260.1 - 9.9e-09 35.0 0.0 3.1e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 PPR repeat family Glyco_hydro_cc PF11790.3 OAJ23261.1 - 1e-50 172.4 2.3 1.4e-50 171.9 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Apolipoprotein PF01442.13 OAJ23262.1 - 0.00013 21.6 12.3 0.00023 20.7 8.5 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain PHTB1_C PF14728.1 OAJ23262.1 - 0.00098 18.0 2.6 0.0012 17.6 1.8 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus OmpH PF03938.9 OAJ23262.1 - 0.0011 18.8 6.4 0.0022 17.9 4.5 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF724 PF05266.9 OAJ23262.1 - 0.0068 16.0 5.0 0.0092 15.6 1.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF724) Baculo_PEP_C PF04513.7 OAJ23262.1 - 0.0088 15.8 3.8 0.56 10.0 0.3 2.6 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus IMD PF08397.6 OAJ23262.1 - 0.014 14.7 0.7 0.019 14.2 0.5 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain Phage_GPO PF05929.6 OAJ23262.1 - 0.017 14.3 5.6 0.03 13.5 3.9 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase GAS PF13851.1 OAJ23262.1 - 0.02 14.0 5.0 0.034 13.3 3.5 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.15 OAJ23262.1 - 0.021 14.5 1.2 0.021 14.5 0.8 1.8 2 0 0 2 2 2 0 Prefoldin subunit IZUMO PF15005.1 OAJ23262.1 - 0.049 13.6 1.0 0.35 10.8 0.1 2.0 1 1 1 2 2 2 0 Izumo sperm-egg fusion Phage_Mu_Gam PF07352.7 OAJ23262.1 - 0.056 12.9 0.4 0.088 12.3 0.3 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein AF0941-like PF14591.1 OAJ23262.1 - 0.14 12.2 0.8 0.21 11.6 0.6 1.3 1 0 0 1 1 1 0 AF0941-like CENP-F_leu_zip PF10473.4 OAJ23262.1 - 0.17 11.7 6.4 0.55 10.0 4.3 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fzo_mitofusin PF04799.8 OAJ23262.1 - 0.18 11.1 8.4 3.3 7.0 0.2 2.6 1 1 1 2 2 2 0 fzo-like conserved region DUF342 PF03961.8 OAJ23262.1 - 0.19 10.1 0.6 0.24 9.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF842 PF05811.8 OAJ23262.1 - 0.35 10.3 6.0 0.39 10.1 2.2 2.2 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Cep57_MT_bd PF06657.8 OAJ23262.1 - 0.39 10.6 3.1 0.69 9.9 1.4 2.0 2 0 0 2 2 1 0 Centrosome microtubule-binding domain of Cep57 Spectrin PF00435.16 OAJ23262.1 - 0.39 11.0 7.5 4.8 7.5 5.2 2.2 1 1 0 1 1 1 0 Spectrin repeat FlxA PF14282.1 OAJ23262.1 - 0.4 10.6 7.3 1.5 8.7 4.8 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF1664 PF07889.7 OAJ23262.1 - 0.43 10.3 3.7 0.85 9.4 0.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Suppressor_APC PF11414.3 OAJ23262.1 - 1.8 8.4 11.9 1.5 8.6 0.0 2.8 2 1 1 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein DUF883 PF05957.8 OAJ23262.1 - 2.4 8.6 9.0 28 5.1 3.2 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Cellulase PF00150.13 OAJ23263.1 - 0.031 13.4 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) PMT PF02366.13 OAJ23264.1 - 3.7e-15 55.9 1.9 4.8e-15 55.5 1.3 1.0 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Auto_anti-p27 PF06677.7 OAJ23265.1 - 0.059 13.1 0.1 7 6.5 0.1 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) SLT_L PF14718.1 OAJ23265.1 - 0.14 12.0 0.5 1 9.2 0.3 2.3 1 1 0 1 1 1 0 Soluble lytic murein transglycosylase L domain DUF4482 PF14818.1 OAJ23266.1 - 0.033 14.8 1.7 0.033 14.8 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) EXS PF03124.9 OAJ23267.1 - 2.9e-73 246.8 32.3 2.8e-42 144.9 9.0 2.2 1 1 1 2 2 2 2 EXS family SPX PF03105.14 OAJ23267.1 - 1.3e-24 87.4 1.4 1.3e-24 87.4 1.0 1.6 2 0 0 2 2 2 1 SPX domain MMR_HSR1 PF01926.18 OAJ23268.1 - 1.4e-17 63.6 0.1 3.4e-14 52.7 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ23268.1 - 1.8e-07 30.5 0.2 1.3e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 OAJ23268.1 - 8.6e-05 22.4 0.6 0.077 12.8 0.1 3.1 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 OAJ23268.1 - 9e-05 21.9 0.0 0.0064 15.9 0.0 2.9 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 OAJ23268.1 - 0.0082 15.3 0.1 0.018 14.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 KAP_NTPase PF07693.9 OAJ23268.1 - 0.066 12.1 0.1 0.3 10.0 0.0 2.0 2 0 0 2 2 2 0 KAP family P-loop domain tRNA-synt_2b PF00587.20 OAJ23270.1 - 4.3e-08 32.9 0.0 5.6e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ACPS PF01648.15 OAJ23271.1 - 6.8e-09 35.5 0.0 1.1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SR-25 PF10500.4 OAJ23271.1 - 0.038 13.4 5.4 0.054 12.9 3.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Helicase_C_2 PF13307.1 OAJ23272.1 - 5.6e-24 84.9 0.1 2.3e-21 76.4 0.0 2.1 1 1 1 2 2 2 2 Helicase C-terminal domain Hist_deacetyl PF00850.14 OAJ23279.1 - 2.2e-27 96.1 0.0 3e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF2786 PF10979.3 OAJ23279.1 - 0.17 11.6 0.3 0.17 11.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) Phage_int_SAM_1 PF02899.12 OAJ23280.1 - 0.017 15.2 0.1 0.93 9.6 0.0 2.4 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain GCR1_C PF12550.3 OAJ23281.1 - 3.7e-19 68.3 2.1 7.2e-19 67.4 1.5 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Bacillus_HBL PF05791.6 OAJ23281.1 - 0.044 13.1 0.1 0.08 12.3 0.1 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) CDC27 PF09507.5 OAJ23282.1 - 0.0037 16.5 7.1 0.0084 15.3 4.9 1.6 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 zf-C2H2 PF00096.21 OAJ23282.1 - 0.04 14.2 5.3 0.21 12.0 3.7 2.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Nop14 PF04147.7 OAJ23282.1 - 2 6.2 21.7 2.8 5.7 15.0 1.2 1 0 0 1 1 1 0 Nop14-like family Methyltransf_23 PF13489.1 OAJ23283.1 - 3.9e-06 26.6 0.0 7.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ23283.1 - 0.046 14.1 0.0 0.33 11.4 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain DUF2457 PF10446.4 OAJ23283.1 - 0.081 11.6 19.6 0.024 13.3 8.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 OAJ23283.1 - 0.81 8.8 8.0 1.6 7.8 5.5 1.4 1 0 0 1 1 1 0 NOA36 protein IFT57 PF10498.4 OAJ23283.1 - 1.4 7.5 2.7 2.7 6.6 1.9 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CDC45 PF02724.9 OAJ23283.1 - 2.6 5.9 9.2 5.4 4.9 6.4 1.5 1 0 0 1 1 1 0 CDC45-like protein RGS PF00615.14 OAJ23284.1 - 2.3e-12 47.0 0.0 2.3e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain His_Phos_1 PF00300.17 OAJ23285.1 - 8.7e-16 58.4 0.0 1.4e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sdh_cyt PF01127.17 OAJ23286.1 - 3.4e-23 81.7 4.9 4.7e-23 81.3 3.4 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Pam16 PF03656.8 OAJ23286.1 - 0.082 12.7 0.3 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Pam16 FSIP1 PF15554.1 OAJ23286.1 - 0.27 9.9 2.5 0.36 9.5 1.7 1.0 1 0 0 1 1 1 0 FSIP1 family AAA_18 PF13238.1 OAJ23287.1 - 7.3e-22 78.0 0.0 2.7e-21 76.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ23287.1 - 6.2e-09 36.7 0.0 1.3e-08 35.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ23287.1 - 0.0041 16.9 0.1 0.59 9.9 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_28 PF13521.1 OAJ23287.1 - 0.0058 16.5 0.0 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 OAJ23287.1 - 0.016 14.4 0.0 0.051 12.7 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 OAJ23287.1 - 0.021 14.7 0.3 0.058 13.3 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 OAJ23287.1 - 0.03 14.0 0.1 0.068 12.9 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 OAJ23287.1 - 0.033 13.3 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 OAJ23287.1 - 0.045 13.8 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 OAJ23287.1 - 0.048 13.8 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 OAJ23287.1 - 0.053 12.9 0.1 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ADK PF00406.17 OAJ23287.1 - 0.056 13.3 0.1 6.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase AAA_29 PF13555.1 OAJ23287.1 - 0.099 12.1 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 OAJ23287.1 - 0.5 9.7 1.7 0.98 8.7 0.0 2.0 2 1 0 2 2 2 0 AAA-like domain DUF383 PF04063.9 OAJ23288.1 - 4.2e-58 196.0 0.0 2.7e-57 193.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 OAJ23288.1 - 1.6e-18 66.0 1.5 3.2e-18 65.0 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) DUF883 PF05957.8 OAJ23288.1 - 0.042 14.2 0.5 0.042 14.2 0.4 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Cpn60_TCP1 PF00118.19 OAJ23289.1 - 2.7e-138 461.6 12.0 3.8e-137 457.8 8.3 2.0 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3808 PF10300.4 OAJ23290.1 - 1.8e-77 260.8 0.0 3e-77 260.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) CRAL_TRIO PF00650.15 OAJ23290.1 - 1.6e-31 108.9 0.0 3.1e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ23290.1 - 4.1e-12 46.0 0.6 1.3e-11 44.4 0.4 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 OAJ23290.1 - 5.2e-12 45.9 0.1 2.4e-11 43.7 0.0 2.1 3 0 0 3 3 3 1 Divergent CRAL/TRIO domain TPR_11 PF13414.1 OAJ23290.1 - 0.00051 19.6 6.6 0.068 12.8 2.3 3.6 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 OAJ23290.1 - 0.15 12.0 10.9 21 5.3 1.2 5.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ23290.1 - 0.74 9.5 7.4 0.93 9.2 0.9 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ23290.1 - 0.75 10.5 8.9 5.4 7.9 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ23290.1 - 2 8.4 12.7 0.34 10.8 2.2 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat Senescence_reg PF04520.8 OAJ23290.1 - 9.6 6.6 12.0 30 5.0 8.3 1.8 1 0 0 1 1 1 0 Senescence regulator Exo_endo_phos PF03372.18 OAJ23291.1 - 3.4e-22 79.5 2.6 1.9e-21 77.1 0.0 2.3 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 OAJ23291.1 - 8.8e-12 44.6 0.0 1.9e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 OAJ23291.1 - 2.8e-06 27.1 3.1 3.3e-05 23.6 2.1 2.4 1 1 0 1 1 1 1 GRF zinc finger zf-C2H2 PF00096.21 OAJ23296.1 - 2.7e-06 27.3 4.7 0.0076 16.5 0.1 2.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 OAJ23296.1 - 4.7e-05 23.3 5.6 0.01 15.9 0.4 2.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 OAJ23296.1 - 8.1e-05 22.6 4.4 0.0034 17.6 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 OAJ23296.1 - 0.00011 22.2 1.9 0.078 13.1 0.2 2.2 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.14 OAJ23296.1 - 0.1 12.2 0.2 0.17 11.6 0.2 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C2H2_6 PF13912.1 OAJ23296.1 - 0.14 12.1 2.1 0.26 11.2 0.1 2.3 1 1 1 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 OAJ23296.1 - 0.14 12.2 0.8 2 8.5 0.5 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 OAJ23296.1 - 0.29 11.4 5.6 0.74 10.2 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger double domain PyrI_C PF02748.10 OAJ23296.1 - 1.1 8.7 3.1 1.3 8.4 0.1 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-H2C2_5 PF13909.1 OAJ23296.1 - 2.4 8.5 5.7 18 5.7 1.2 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Ank_2 PF12796.2 OAJ23297.1 - 1.6e-54 182.1 6.0 3.4e-20 72.1 0.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ23297.1 - 4.6e-36 120.8 6.4 4.6e-09 35.6 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat SPX PF03105.14 OAJ23297.1 - 3e-33 115.7 0.6 1.5e-18 67.6 0.0 3.0 3 1 0 3 3 3 2 SPX domain Ank_4 PF13637.1 OAJ23297.1 - 3.7e-32 110.1 3.8 5.4e-11 42.7 0.0 5.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ23297.1 - 1.2e-29 101.6 13.0 6.2e-06 26.2 0.0 7.6 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ23297.1 - 1.5e-22 77.4 1.6 0.0031 17.6 0.0 7.8 8 0 0 8 8 8 5 Ankyrin repeat GDPD PF03009.12 OAJ23297.1 - 1.9e-12 47.2 0.0 3.6e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family RVT_2 PF07727.9 OAJ23299.1 - 7.6e-68 228.1 0.0 1e-67 227.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ23299.1 - 2.2e-22 79.3 0.1 1.4e-21 76.8 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ23299.1 - 1.3e-08 34.3 0.3 1.7e-07 30.7 0.0 2.4 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-CCHC PF00098.18 OAJ23299.1 - 2e-07 30.5 8.0 0.00022 21.0 1.0 2.6 2 0 0 2 2 2 2 Zinc knuckle UBN2 PF14223.1 OAJ23299.1 - 8.5e-05 22.3 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 OAJ23299.1 - 0.0011 18.4 0.1 0.013 15.0 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 OAJ23299.1 - 0.0041 16.6 0.0 0.0095 15.4 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1820 PF08850.6 OAJ23299.1 - 0.057 13.5 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1820) RVP PF00077.15 OAJ23299.1 - 0.2 11.6 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease HpaP PF09483.5 OAJ23300.1 - 0.23 11.4 8.6 0.27 11.1 6.0 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Herpes_capsid PF06112.6 OAJ23300.1 - 0.91 9.5 7.8 1.1 9.2 5.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Stm1_N PF09598.5 OAJ23300.1 - 2.8 8.7 14.4 4.6 8.0 9.4 1.8 1 1 1 2 2 2 0 Stm1 Pheromone PF08015.6 OAJ23300.1 - 5.2 7.9 7.2 89 4.0 5.0 2.2 1 1 0 1 1 1 0 Fungal mating-type pheromone Med3 PF11593.3 OAJ23300.1 - 7.3 5.7 8.5 7.6 5.6 5.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal rve PF00665.21 OAJ23301.1 - 1.8e-14 53.9 0.0 7.7e-14 51.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ23301.1 - 3.1e-07 29.9 0.0 5.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ23301.1 - 0.0003 21.2 0.3 0.00086 19.7 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAJ23301.1 - 0.0089 15.9 0.0 0.023 14.6 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ23301.1 - 0.012 15.4 1.3 0.036 13.8 0.1 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DDE_Tnp_4 PF13359.1 OAJ23302.1 - 6.9e-32 110.2 0.0 9.2e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ23302.1 - 2.9e-06 26.7 0.0 3.6e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Plant transposon protein HTH_Tnp_4 PF13613.1 OAJ23302.1 - 1.3e-05 24.5 0.0 4.2e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 OAJ23302.1 - 2.3e-05 24.0 0.1 0.00021 20.9 0.1 2.1 1 1 0 1 1 1 1 Transposase DDE domain HTH_23 PF13384.1 OAJ23302.1 - 0.072 12.7 0.0 0.29 10.8 0.0 2.1 1 0 0 1 1 1 0 Homeodomain-like domain Ribosomal_60s PF00428.14 OAJ23303.1 - 3.3e-26 91.5 7.3 3.9e-26 91.2 5.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein OAD_beta PF03977.8 OAJ23303.1 - 0.059 12.0 0.3 0.069 11.8 0.2 1.1 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit Peptidase_C27 PF05407.7 OAJ23303.1 - 0.092 12.4 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Rubella virus endopeptidase CRM1_C PF08767.6 OAJ23304.1 - 6.8e-121 403.0 1.0 6.8e-121 403.0 0.7 2.5 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 OAJ23304.1 - 4.1e-40 137.1 2.1 4.1e-40 137.1 1.5 3.9 4 1 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 OAJ23304.1 - 5.1e-13 48.7 0.6 2.2e-12 46.7 0.4 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF1654 PF07867.6 OAJ23304.1 - 0.14 11.5 1.8 13 5.2 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) DnaJ PF00226.26 OAJ23305.1 - 8.5e-07 28.6 0.1 1.3e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain HsbA PF12296.3 OAJ23306.1 - 2.5e-14 53.1 7.0 4e-14 52.5 4.8 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A ALS_ss_C PF10369.4 OAJ23306.1 - 0.067 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Small subunit of acetolactate synthase TPP_enzyme_C PF02775.16 OAJ23306.1 - 0.07 12.7 0.1 0.091 12.3 0.1 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pkinase PF00069.20 OAJ23307.1 - 1.6e-69 233.9 0.0 2e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ23307.1 - 2.1e-30 105.6 0.0 2.8e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ23307.1 - 0.0021 17.0 0.0 0.18 10.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.6 OAJ23307.1 - 0.051 12.4 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 OAJ23307.1 - 0.089 12.5 0.0 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF544 PF04424.8 OAJ23312.1 - 5.4e-15 55.2 0.0 1.1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF544) InaF-motif PF15018.1 OAJ23313.1 - 0.1 12.0 0.8 0.16 11.4 0.2 1.6 2 0 0 2 2 2 0 TRP-interacting helix Hydrolase PF00702.21 OAJ23317.1 - 9.8e-07 29.4 0.1 3.2e-06 27.6 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ23317.1 - 0.00083 19.0 0.2 0.0012 18.4 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Transposase_21 PF02992.9 OAJ23318.1 - 1.2e-12 47.3 0.0 2.2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ23318.1 - 0.14 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) CDC45 PF02724.9 OAJ23318.1 - 3.7 5.4 5.7 6.3 4.6 3.4 1.7 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.7 OAJ23318.1 - 5 6.3 10.3 8.9 5.4 7.1 1.4 1 0 0 1 1 1 0 SDA1 DIM1 PF02966.11 OAJ23322.1 - 1.7e-66 221.7 0.1 1.9e-66 221.5 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 OAJ23322.1 - 0.0044 16.6 0.0 0.0056 16.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 OAJ23322.1 - 0.0071 16.3 0.0 0.015 15.2 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ23322.1 - 0.021 14.9 0.0 0.03 14.5 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAJ23322.1 - 0.093 12.8 0.1 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like Myb_Cef PF11831.3 OAJ23324.1 - 1.5e-53 181.3 0.0 1.5e-53 181.3 0.0 3.8 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 OAJ23324.1 - 1.4e-22 79.4 4.7 3.3e-11 43.0 0.4 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ23324.1 - 6.2e-20 71.0 8.5 3e-13 49.6 2.7 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain HALZ PF02183.13 OAJ23324.1 - 0.0052 16.4 2.1 0.019 14.6 0.6 2.6 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF217 PF02697.9 OAJ23324.1 - 0.49 10.6 5.4 0.2 11.9 0.5 2.8 2 0 0 2 2 2 0 Uncharacterized ACR, COG1753 DUF3090 PF11290.3 OAJ23324.1 - 0.99 8.8 7.4 0.25 10.7 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) Calpain_III PF01067.17 OAJ23325.1 - 1.4e-21 76.7 0.0 1.1e-12 47.7 0.0 3.8 4 0 0 4 4 4 2 Calpain large subunit, domain III Peptidase_C2 PF00648.16 OAJ23325.1 - 8.2e-18 64.4 0.0 1.4e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Sec1 PF00995.18 OAJ23329.1 - 1.5e-30 106.3 0.1 3.1e-14 52.5 0.0 2.1 2 0 0 2 2 2 2 Sec1 family LSM PF01423.17 OAJ23329.1 - 0.0052 16.3 0.0 2.9 7.5 0.0 2.3 2 0 0 2 2 2 2 LSM domain PDZ PF00595.19 OAJ23329.1 - 0.063 13.4 0.2 19 5.5 0.0 2.3 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) Acetyltransf_1 PF00583.19 OAJ23334.1 - 1.6e-10 40.8 0.2 0.00012 22.0 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ23334.1 - 3.3e-05 23.9 0.0 0.19 11.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ23334.1 - 9.1e-05 22.1 0.1 0.1 12.3 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_10 PF13673.1 OAJ23334.1 - 0.0011 19.0 0.0 0.91 9.6 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 OAJ23334.1 - 0.035 13.9 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAJ23334.1 - 0.041 13.8 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAT PF02259.18 OAJ23335.1 - 3.3e-66 223.6 2.0 3.3e-66 223.6 1.4 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 OAJ23335.1 - 1.7e-23 83.3 0.0 5.1e-23 81.7 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 OAJ23335.1 - 0.013 14.9 0.5 0.033 13.6 0.3 1.7 1 0 0 1 1 1 0 FATC domain Ribosomal_L13e PF01294.13 OAJ23336.1 - 1.5e-59 200.4 7.0 2e-59 200.0 4.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_60s PF00428.14 OAJ23338.1 - 5.3 7.5 13.4 1.9 8.9 6.8 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein U3_assoc_6 PF08640.6 OAJ23340.1 - 3.9e-13 48.9 0.5 2.7e-12 46.2 0.1 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 MoaC PF01967.16 OAJ23342.1 - 5.8e-41 139.3 1.7 2.1e-21 76.0 0.0 2.2 2 0 0 2 2 2 2 MoaC family SRP-alpha_N PF04086.8 OAJ23342.1 - 0.12 11.6 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Mob_synth_C PF06463.8 OAJ23343.1 - 8.7e-32 109.5 0.0 3.3e-31 107.6 0.0 1.9 1 1 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 OAJ23343.1 - 2.8e-25 89.4 0.0 4.3e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 OAJ23343.1 - 6.6e-06 26.2 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 OAJ23343.1 - 0.00024 21.1 0.0 0.00048 20.1 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain ELFV_dehydrog PF00208.16 OAJ23347.1 - 2.2e-48 164.9 0.2 2.7e-48 164.6 0.1 1.0 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF390 PF04094.9 OAJ23347.1 - 0.022 12.8 0.2 0.029 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) SKN1 PF03935.10 OAJ23348.1 - 6.6e-98 328.0 0.0 2.1e-59 201.0 0.0 2.1 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Lipase_3 PF01764.20 OAJ23349.1 - 4.1e-13 49.1 0.0 6.9e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 OAJ23349.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 OAJ23349.1 - 0.049 13.3 0.0 0.12 12.0 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family TMEM171 PF15471.1 OAJ23349.1 - 0.094 11.4 2.9 10 4.7 2.4 2.2 2 0 0 2 2 2 0 Transmembrane protein family 171 DUF2974 PF11187.3 OAJ23349.1 - 0.14 11.5 0.0 0.34 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Strabismus PF06638.6 OAJ23349.1 - 0.93 7.7 2.6 1.4 7.1 1.8 1.2 1 0 0 1 1 1 0 Strabismus protein Oxidored_FMN PF00724.15 OAJ23351.1 - 0.0036 16.3 0.0 0.005 15.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SKN1 PF03935.10 OAJ23352.1 - 5.7e-20 70.9 0.0 6e-20 70.8 0.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.10 OAJ23353.1 - 1.7e-12 46.3 0.0 2.2e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Aconitase PF00330.15 OAJ23354.1 - 2.7e-174 580.0 0.0 5.8e-174 578.9 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAJ23354.1 - 3.7e-44 150.0 0.0 6.4e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain NUDIX PF00293.23 OAJ23355.1 - 4.1e-15 55.6 0.0 7.2e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 OAJ23355.1 - 8.3e-11 42.1 1.8 3.9e-10 39.9 1.2 2.2 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain SKN1 PF03935.10 OAJ23356.1 - 5.8e-132 440.3 1.4 6.6e-93 311.5 0.7 2.0 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.10 OAJ23357.1 - 3.9e-137 457.4 15.2 4.9e-136 453.8 10.5 2.1 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.10 OAJ23358.1 - 2e-174 580.4 5.0 5.3e-93 311.8 0.6 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Clathrin_propel PF01394.15 OAJ23358.1 - 0.0083 16.3 0.5 9.3 6.7 0.0 2.9 2 0 0 2 2 2 2 Clathrin propeller repeat Corona_6B_7B PF03262.8 OAJ23358.1 - 0.11 11.7 0.0 9.1 5.4 0.0 2.1 2 0 0 2 2 2 0 Coronavirus 6B/7B protein WGG PF10273.4 OAJ23359.1 - 1.1e-21 76.7 0.0 2e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 OAJ23359.1 - 0.021 14.8 1.3 0.021 14.8 0.9 1.6 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) Utp14 PF04615.8 OAJ23359.1 - 0.12 10.5 9.1 0.18 9.9 6.3 1.2 1 0 0 1 1 1 0 Utp14 protein CDC45 PF02724.9 OAJ23359.1 - 2.5 6.0 11.8 3.4 5.5 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 OAJ23359.1 - 4 6.0 18.7 6.8 5.3 12.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pox_RNA_Pol_19 PF05320.7 OAJ23359.1 - 10 5.8 8.3 21 4.8 5.8 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Oxysterol_BP PF01237.13 OAJ23365.1 - 8.2e-85 284.3 0.0 1e-84 284.1 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein FSH1 PF03959.8 OAJ23366.1 - 1.5e-53 181.3 0.0 1.8e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 OAJ23366.1 - 1.4e-07 31.5 1.2 2.6e-05 24.1 0.0 2.4 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ23366.1 - 4.7e-05 23.1 0.0 6.9e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAJ23366.1 - 0.0024 17.3 0.1 0.025 14.0 0.1 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.13 OAJ23366.1 - 0.019 14.2 0.1 0.078 12.2 0.1 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 OAJ23366.1 - 0.034 13.7 0.0 0.73 9.3 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.6 OAJ23366.1 - 0.13 11.9 0.0 5.8 6.5 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal IGPD PF00475.13 OAJ23367.1 - 4.1e-60 201.8 0.8 5e-60 201.5 0.3 1.3 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase DUF2917 PF11142.3 OAJ23367.1 - 0.1 11.7 0.1 0.35 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2917) DUF913 PF06025.7 OAJ23369.1 - 9.3e-92 307.6 0.0 9.3e-92 307.6 0.0 4.4 5 0 0 5 5 5 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 OAJ23369.1 - 3.5e-71 240.2 0.1 1.2e-70 238.4 0.1 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 OAJ23369.1 - 7.7e-25 86.9 2.8 5.7e-24 84.1 1.9 2.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) UBA PF00627.26 OAJ23369.1 - 1e-09 37.9 0.1 3e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain COX15-CtaA PF02628.10 OAJ23370.1 - 1.5e-78 263.6 9.5 2.3e-77 259.8 6.6 2.6 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein GYF PF02213.11 OAJ23371.1 - 0.0038 16.7 0.0 0.0094 15.5 0.0 1.6 1 0 0 1 1 1 1 GYF domain ParA PF10609.4 OAJ23372.1 - 4.3e-32 109.8 0.0 9.5e-32 108.7 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 OAJ23372.1 - 6.2e-08 32.2 0.8 0.0015 17.9 0.5 2.3 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 OAJ23372.1 - 0.00073 18.6 0.2 0.0013 17.7 0.1 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.1 OAJ23372.1 - 0.005 16.2 0.0 0.0084 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 OAJ23372.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SelB-wing_3 PF09107.6 OAJ23372.1 - 0.032 13.6 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Fer4_NifH PF00142.13 OAJ23372.1 - 0.059 12.5 0.0 4.6 6.3 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Nucleoplasmin PF03066.10 OAJ23372.1 - 0.085 12.3 0.2 0.085 12.3 0.1 1.8 2 0 0 2 2 2 0 Nucleoplasmin NB-ARC PF00931.17 OAJ23372.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain VirE PF05272.6 OAJ23372.1 - 0.19 11.1 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E DUF4611 PF15387.1 OAJ23372.1 - 1.6 8.9 5.8 6.8 6.9 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) ABC_tran PF00005.22 OAJ23373.1 - 2.1e-42 144.6 0.0 6.5e-24 84.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 OAJ23373.1 - 9.1e-35 120.3 16.9 3.9e-19 69.1 2.2 3.4 4 0 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.14 OAJ23373.1 - 2.5e-09 36.6 0.0 7.5e-05 22.0 0.0 3.6 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 OAJ23373.1 - 5.1e-05 22.7 0.2 0.2 11.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 OAJ23373.1 - 5.9e-05 23.1 0.0 1.7 8.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 OAJ23373.1 - 9.5e-05 22.5 0.2 0.28 11.3 0.0 3.7 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 OAJ23373.1 - 0.00011 21.2 0.0 0.031 13.1 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 OAJ23373.1 - 0.0016 17.8 1.8 0.052 13.0 0.0 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ23373.1 - 0.0038 17.2 7.9 0.011 15.6 1.2 3.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 OAJ23373.1 - 0.004 16.6 0.0 0.27 10.6 0.0 2.5 2 1 0 2 2 2 1 AAA-like domain KaiC PF06745.8 OAJ23373.1 - 0.016 14.3 0.2 0.37 9.8 0.0 2.3 2 0 0 2 2 2 0 KaiC TrwB_AAD_bind PF10412.4 OAJ23373.1 - 0.11 11.1 0.5 10 4.6 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.1 OAJ23373.1 - 0.13 13.1 1.1 0.81 10.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 OAJ23373.1 - 0.24 10.6 0.1 5.7 6.1 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein cobW PF02492.14 OAJ23373.1 - 0.28 10.5 1.6 0.99 8.8 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 OAJ23373.1 - 0.44 10.8 2.0 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 OAJ23373.1 - 0.72 9.6 3.5 0.21 11.3 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function DUF87 CDC45 PF02724.9 OAJ23373.1 - 3.1 5.7 3.7 4.8 5.0 2.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 OAJ23374.1 - 0.68 8.6 8.1 0.98 8.0 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 OAJ23374.1 - 1.2 7.1 5.6 1.8 6.5 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2414 PF10309.4 OAJ23375.1 - 2.8e-06 26.8 0.0 4.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) DASH_Spc19 PF08287.6 OAJ23376.1 - 3.5e-11 42.9 6.9 2.7e-10 40.0 4.7 2.3 1 1 0 1 1 1 1 Spc19 Filament PF00038.16 OAJ23376.1 - 0.0029 17.1 3.6 0.0046 16.4 2.5 1.3 1 0 0 1 1 1 1 Intermediate filament protein BLOC1_2 PF10046.4 OAJ23376.1 - 0.043 13.9 5.3 1.5 8.9 1.1 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WASH_WAHD PF11945.3 OAJ23376.1 - 0.21 10.8 4.7 2.7 7.2 3.2 2.2 1 1 1 2 2 2 0 WAHD domain of WASH complex DUF812 PF05667.6 OAJ23376.1 - 0.21 10.0 11.6 0.24 9.8 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Myosin_tail_1 PF01576.14 OAJ23376.1 - 0.27 8.9 12.7 0.25 8.9 0.9 2.0 2 0 0 2 2 2 0 Myosin tail IFT43 PF15305.1 OAJ23376.1 - 0.61 10.1 3.8 1.1 9.3 2.4 1.5 1 1 0 1 1 1 0 Intraflagellar transport protein 43 Atg14 PF10186.4 OAJ23376.1 - 0.79 8.6 9.4 0.29 10.0 2.4 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Sipho_Gp157 PF05565.6 OAJ23376.1 - 4.6 6.7 7.2 9 5.8 0.6 2.3 1 1 1 2 2 2 0 Siphovirus Gp157 MIP PF00230.15 OAJ23378.1 - 1.6e-45 155.3 5.9 2.4e-45 154.7 4.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein Apc1 PF12859.2 OAJ23378.1 - 0.52 10.5 7.2 0.35 11.1 2.1 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 1 Zip PF02535.17 OAJ23378.1 - 2.2 7.1 8.7 1.6 7.7 3.5 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Apt1 PF10351.4 OAJ23383.1 - 1.4e-104 350.5 0.2 1.4e-104 350.5 0.1 2.5 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 OAJ23383.1 - 1.1e-73 248.3 0.0 2.2e-73 247.3 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 OAJ23383.1 - 3.1e-42 144.1 0.0 6e-42 143.2 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 OAJ23383.1 - 1.1e-34 119.4 0.0 2.1e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 OAJ23383.1 - 1.6e-20 73.4 0.0 2.8e-19 69.4 0.0 2.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain ARID PF01388.16 OAJ23384.1 - 7.8e-15 54.4 0.0 7.8e-15 54.4 0.0 3.8 4 0 0 4 4 4 1 ARID/BRIGHT DNA binding domain Pkinase PF00069.20 OAJ23385.1 - 4e-68 229.3 0.0 5.9e-68 228.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ23385.1 - 5.1e-30 104.4 0.1 9e-29 100.3 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ23385.1 - 5.8e-07 28.7 1.7 0.00013 21.0 0.0 3.0 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 OAJ23385.1 - 0.017 14.1 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VWA_2 PF13519.1 OAJ23386.1 - 1.5e-11 44.6 0.0 2.4e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 OAJ23386.1 - 1.1e-05 25.2 0.0 4.8e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain TATR PF03430.8 OAJ23388.1 - 1.1 7.8 2.6 1.7 7.2 1.8 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Abhydrolase_3 PF07859.8 OAJ23389.1 - 2.6e-24 85.9 0.0 3.3e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ23389.1 - 0.0013 18.4 0.1 0.0025 17.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 OAJ23389.1 - 0.0054 16.1 0.1 0.0095 15.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DLH PF01738.13 OAJ23389.1 - 0.023 13.9 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 OAJ23389.1 - 0.03 14.2 1.1 0.64 9.8 0.7 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_114 PF03537.8 OAJ23389.1 - 0.049 13.4 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 WD40 PF00400.27 OAJ23390.1 - 8.8e-17 60.2 11.7 1.6e-05 24.6 0.3 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Rax2 PF12768.2 OAJ23390.1 - 0.005 16.0 0.0 0.012 14.8 0.0 1.6 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DPPIV_N PF00930.16 OAJ23390.1 - 0.01 14.4 0.9 0.28 9.7 0.5 2.5 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1748 PF08520.5 OAJ23391.1 - 1.9e-27 94.6 0.0 2.1e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Sad1_UNC PF07738.8 OAJ23392.1 - 7.8e-07 28.9 0.1 0.039 13.7 0.1 2.9 2 1 0 2 2 2 2 Sad1 / UNC-like C-terminal FlgD_ig PF13860.1 OAJ23392.1 - 0.093 12.4 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 FlgD Ig-like domain PRKCSH-like PF12999.2 OAJ23393.1 - 6e-43 146.4 6.5 6e-43 146.4 4.5 2.2 1 1 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 OAJ23393.1 - 1.1e-27 96.3 0.1 2.8e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 OAJ23393.1 - 4.7e-09 36.9 1.5 1.1e-08 35.7 1.1 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF2968 PF11180.3 OAJ23393.1 - 0.0016 17.8 6.7 0.0077 15.6 4.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2968) IncA PF04156.9 OAJ23393.1 - 0.0071 15.9 3.1 0.12 11.9 1.1 2.4 2 0 0 2 2 2 1 IncA protein bZIP_1 PF00170.16 OAJ23393.1 - 0.037 13.9 9.9 0.66 9.9 0.7 2.6 2 0 0 2 2 2 0 bZIP transcription factor DUF3584 PF12128.3 OAJ23393.1 - 0.038 11.3 6.1 0.0043 14.4 1.5 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Fmp27_WPPW PF10359.4 OAJ23393.1 - 0.078 11.3 0.3 0.13 10.6 0.2 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CDC37_N PF03234.9 OAJ23393.1 - 0.12 12.7 4.4 0.28 11.5 1.3 2.2 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Seryl_tRNA_N PF02403.17 OAJ23393.1 - 8.2 6.4 12.3 11 6.1 4.5 2.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Glycoprotein_G PF00802.14 OAJ23394.1 - 0.0025 17.0 15.1 0.0041 16.3 10.5 1.3 1 0 0 1 1 1 1 Pneumovirus attachment glycoprotein G QueF_N PF14819.1 OAJ23394.1 - 0.1 12.7 1.7 10 6.2 0.0 3.0 2 1 1 3 3 3 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term DUF4106 PF13388.1 OAJ23394.1 - 0.97 8.3 3.9 2 7.2 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Polysacc_deac_1 PF01522.16 OAJ23398.1 - 8.2e-17 60.9 0.0 1.3e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Ets PF00178.17 OAJ23399.1 - 0.035 14.2 0.2 0.14 12.2 0.0 2.1 3 0 0 3 3 3 0 Ets-domain DUF3106 PF11304.3 OAJ23399.1 - 0.073 13.4 6.8 0.084 13.3 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Phage_holin_2 PF04550.7 OAJ23400.1 - 0.051 13.6 3.1 1.4 9.0 0.3 2.1 1 1 1 2 2 2 0 Phage holin family 2 DUF637 PF04830.8 OAJ23400.1 - 0.16 11.6 5.8 0.17 11.5 2.9 1.6 1 1 1 2 2 2 0 Possible hemagglutinin (DUF637) DUF3808 PF10300.4 OAJ23401.1 - 7.3e-83 278.6 0.0 2.1e-82 277.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.12 OAJ23401.1 - 1.9e-05 24.2 1.2 0.048 13.5 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ23401.1 - 0.00014 21.3 0.5 0.0022 17.6 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ23401.1 - 0.00051 19.6 1.6 0.31 10.6 0.0 3.4 3 1 0 3 3 3 2 TPR repeat TPR_6 PF13174.1 OAJ23401.1 - 0.018 15.4 0.6 4.5 7.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ23401.1 - 0.092 13.4 0.3 48 4.7 0.1 3.5 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ23401.1 - 0.12 12.3 4.2 3.7 7.5 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ23401.1 - 0.12 12.2 0.3 14 5.7 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ23401.1 - 0.13 11.9 0.9 1.3 8.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HIT PF01230.18 OAJ23402.1 - 7.7e-23 80.8 0.1 1.3e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 OAJ23402.1 - 7.7e-11 42.2 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 OAJ23402.1 - 3.3e-06 26.7 0.0 5.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Phage_integrase PF00589.17 OAJ23404.1 - 9.5e-05 22.1 0.0 0.00032 20.4 0.0 1.7 2 0 0 2 2 2 1 Phage integrase family Pkinase PF00069.20 OAJ23405.1 - 2.9e-34 118.3 0.0 3.3e-32 111.6 0.0 2.9 1 1 0 1 1 1 1 Protein kinase domain FHA PF00498.21 OAJ23405.1 - 9.4e-10 38.4 0.1 1.7e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 FHA domain Pkinase_Tyr PF07714.12 OAJ23405.1 - 1.1e-09 37.7 0.0 4.1e-07 29.3 0.0 2.3 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ23405.1 - 0.095 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like AA_permease PF00324.16 OAJ23406.1 - 1.1e-130 436.2 38.6 1.3e-130 435.9 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAJ23406.1 - 2.7e-42 144.8 43.0 3.4e-42 144.4 29.8 1.1 1 0 0 1 1 1 1 Amino acid permease RVT_3 PF13456.1 OAJ23407.1 - 0.0079 15.9 0.0 0.021 14.5 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase-like LRR_4 PF12799.2 OAJ23408.1 - 2.6e-13 49.2 18.1 4.5e-06 26.1 0.6 5.5 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ23408.1 - 8e-10 38.3 8.4 8e-10 38.3 5.8 4.0 6 0 0 6 6 6 1 Leucine rich repeat LRR_1 PF00560.28 OAJ23408.1 - 0.00028 20.4 15.8 0.52 10.5 0.6 7.5 8 1 1 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.1 OAJ23408.1 - 0.00091 19.0 17.2 9.1 6.6 0.3 7.5 8 0 0 8 8 8 2 Leucine Rich repeat LRR_9 PF14580.1 OAJ23408.1 - 0.0079 15.7 1.0 0.16 11.4 0.3 2.4 2 1 0 2 2 2 1 Leucine-rich repeat LSM PF01423.17 OAJ23409.1 - 1.9e-16 59.3 0.1 2.3e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain PROCN PF08083.6 OAJ23411.1 - 1.5e-207 688.9 5.6 2.4e-207 688.3 3.9 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 OAJ23411.1 - 1.6e-126 420.2 0.7 2.6e-126 419.5 0.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 OAJ23411.1 - 1.1e-91 304.4 1.3 2.9e-91 303.0 0.9 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 OAJ23411.1 - 5.2e-78 259.9 2.4 5.2e-78 259.9 1.7 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 OAJ23411.1 - 2.5e-61 205.2 0.0 4.7e-61 204.3 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 OAJ23411.1 - 1.2e-41 140.4 0.0 2.7e-41 139.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 OAJ23411.1 - 3.4e-35 120.4 0.0 6.9e-35 119.4 0.0 1.5 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 OAJ23411.1 - 0.0094 15.6 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FHA PF00498.21 OAJ23412.1 - 1.3e-05 25.2 0.0 3.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain DUF2370 PF10176.4 OAJ23414.1 - 1.5e-68 230.6 0.0 6.5e-68 228.5 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 OAJ23414.1 - 0.051 13.7 4.3 0.094 12.9 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF202) BAF1_ABF1 PF04684.8 OAJ23414.1 - 0.092 11.5 0.1 0.2 10.4 0.0 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ECH PF00378.15 OAJ23416.1 - 2.2e-35 121.9 0.0 3.4e-23 82.0 0.0 2.5 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase family Abhydrolase_5 PF12695.2 OAJ23420.1 - 9.4e-08 31.9 0.4 7.6e-07 28.9 0.1 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ23420.1 - 0.00011 22.1 1.6 0.00029 20.7 1.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 OAJ23420.1 - 0.0031 16.8 0.0 0.006 15.8 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 OAJ23420.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 OAJ23420.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 OAJ23420.1 - 0.21 11.1 2.7 0.63 9.5 1.9 1.8 1 1 0 1 1 1 0 PGAP1-like protein DUF1720 PF08226.6 OAJ23421.1 - 4.2 7.5 14.6 0.13 12.3 2.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1720) NDUFA12 PF05071.11 OAJ23422.1 - 3e-10 40.4 0.1 5.2e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 UDPG_MGDP_dh_N PF03721.9 OAJ23423.1 - 4.9e-60 202.0 0.3 1.3e-59 200.7 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 OAJ23423.1 - 2.4e-34 117.6 0.1 1e-32 112.4 0.0 2.8 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 OAJ23423.1 - 8.4e-32 109.2 0.0 1.6e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 OAJ23423.1 - 0.00085 19.0 0.1 0.067 12.9 0.0 2.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 OAJ23423.1 - 0.0039 17.5 0.2 4.3 7.8 0.1 3.1 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent UBX PF00789.15 OAJ23425.1 - 5e-07 29.6 0.0 8.1e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 UBX domain HhH-GPD PF00730.20 OAJ23426.1 - 2.9e-14 53.2 0.0 6.3e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 OAJ23426.1 - 5.2e-14 51.6 0.0 1.5e-13 50.1 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain Bul1_C PF04426.7 OAJ23426.1 - 0.012 14.8 2.1 0.022 13.9 1.4 1.4 1 0 0 1 1 1 0 Bul1 C terminus PG_binding_2 PF08823.6 OAJ23426.1 - 0.046 13.8 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain HHH PF00633.18 OAJ23426.1 - 0.051 13.2 0.1 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 OAJ23426.1 - 0.39 10.9 3.7 1.1 9.5 2.6 1.8 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III EAP30 PF04157.11 OAJ23427.1 - 9.4e-42 142.6 0.0 1.9e-41 141.6 0.0 1.5 1 1 0 1 1 1 1 EAP30/Vps36 family QLQ PF08880.6 OAJ23427.1 - 0.11 11.9 0.8 0.26 10.7 0.3 1.8 2 0 0 2 2 2 0 QLQ Defensin_2 PF01097.13 OAJ23428.1 - 0.035 13.8 1.4 0.095 12.4 1.0 1.7 1 0 0 1 1 1 0 Arthropod defensin TPT PF03151.11 OAJ23429.1 - 1.4e-31 109.2 3.8 1.4e-31 109.2 2.7 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 OAJ23429.1 - 1.5e-10 41.1 19.1 1.7e-05 24.8 3.3 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 OAJ23429.1 - 0.00026 19.9 13.0 0.00083 18.3 8.7 1.8 1 1 0 1 1 1 1 UAA transporter family Bd3614_N PF14442.1 OAJ23429.1 - 0.017 15.0 1.3 0.045 13.7 0.9 1.7 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal MFS_Mycoplasma PF07672.8 OAJ23429.1 - 0.06 12.5 0.2 0.06 12.5 0.1 2.5 3 0 0 3 3 3 0 Mycoplasma MFS transporter EmrE PF13536.1 OAJ23429.1 - 8.8 6.5 19.9 3.2 7.9 3.7 2.8 2 2 0 2 2 2 0 Multidrug resistance efflux transporter ADH_zinc_N_2 PF13602.1 OAJ23430.1 - 7.3e-09 36.5 0.0 3.1e-08 34.5 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ23430.1 - 0.00015 21.4 0.4 0.0003 20.5 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ23430.1 - 0.011 15.2 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF4137 PF13593.1 OAJ23430.1 - 1.6 7.7 0.1 2.5 7.1 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) GAS PF13851.1 OAJ23431.1 - 0.055 12.6 0.4 0.11 11.7 0.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Serglycin PF04360.7 OAJ23431.1 - 0.084 12.6 4.5 0.15 11.7 3.1 1.4 1 0 0 1 1 1 0 Serglycin HALZ PF02183.13 OAJ23431.1 - 0.097 12.3 0.5 0.23 11.2 0.4 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper SAP PF02037.22 OAJ23432.1 - 4.6e-10 38.7 0.4 7.8e-10 38.0 0.3 1.4 1 0 0 1 1 1 1 SAP domain Pex14_N PF04695.8 OAJ23432.1 - 0.0046 17.0 0.6 0.0046 17.0 0.4 3.9 4 0 0 4 4 4 2 Peroxisomal membrane anchor protein (Pex14p) conserved region RPA_interact_N PF14766.1 OAJ23432.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 Replication protein A interacting N-terminal Sec3_C PF09763.4 OAJ23432.1 - 0.35 8.9 1.1 0.54 8.3 0.8 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 Lactamase_B PF00753.22 OAJ23433.1 - 5.4e-22 78.3 2.6 8.1e-22 77.8 1.8 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RCC1 PF00415.13 OAJ23434.1 - 5.3e-23 80.9 12.0 0.00044 20.3 0.3 8.5 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ23434.1 - 5.3e-12 45.0 19.3 6.4e-08 32.0 1.2 6.7 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Mitofilin PF09731.4 OAJ23436.1 - 7.2e-68 229.6 37.3 6e-34 117.6 13.7 3.4 2 1 2 4 4 4 4 Mitochondrial inner membrane protein Thiolase_N PF00108.18 OAJ23437.1 - 3.1e-96 321.4 2.6 4.8e-96 320.7 1.8 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAJ23437.1 - 2.9e-43 146.1 1.6 4.3e-42 142.4 0.4 2.5 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 OAJ23437.1 - 4.5e-06 26.3 2.9 3.7e-05 23.3 0.8 2.5 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain DUF1264 PF06884.6 OAJ23439.1 - 8.2e-46 155.5 0.0 1.2e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) SRPRB PF09439.5 OAJ23440.1 - 9.6e-10 37.9 0.1 2e-09 36.9 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 OAJ23440.1 - 0.0013 19.1 0.0 0.0026 18.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein DUF374 PF04028.8 OAJ23440.1 - 0.0054 15.9 0.8 0.014 14.5 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF374) MMR_HSR1 PF01926.18 OAJ23440.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 OAJ23440.1 - 0.051 12.7 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 OAJ23440.1 - 0.061 12.8 0.3 0.061 12.8 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain G-alpha PF00503.15 OAJ23440.1 - 0.068 11.8 0.1 0.13 10.8 0.1 1.4 1 0 0 1 1 1 0 G-protein alpha subunit SMC_N PF02463.14 OAJ23440.1 - 0.078 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 OAJ23440.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4210 PF13915.1 OAJ23444.1 - 3.5e-17 62.4 1.7 3e-16 59.4 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 OAJ23444.1 - 1.2e-11 44.2 0.0 2.7e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis adh_short PF00106.20 OAJ23444.1 - 0.0037 17.1 1.1 0.011 15.6 0.8 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Aldose_epim PF01263.15 OAJ23445.1 - 5.8e-30 104.4 0.0 7.2e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase PRELI PF04707.9 OAJ23446.1 - 3.4e-18 65.6 0.8 7.4e-06 25.6 0.0 3.3 2 1 1 3 3 3 3 PRELI-like family Hs1pro-1_N PF07231.7 OAJ23446.1 - 0.0019 17.8 0.1 0.0039 16.7 0.1 1.4 1 1 0 1 1 1 1 Hs1pro-1 N-terminus Pkinase PF00069.20 OAJ23447.1 - 4.6e-42 143.9 0.0 4.3e-24 85.0 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ23447.1 - 3.2e-20 72.2 0.0 2.4e-10 39.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ23447.1 - 7.3e-09 34.9 0.0 9.3e-07 28.0 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 OAJ23447.1 - 0.036 13.7 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family ECH PF00378.15 OAJ23448.1 - 1.2e-18 67.1 0.3 2.7e-17 62.7 0.2 2.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 OAJ23448.1 - 7.3e-09 35.8 0.7 0.0032 17.6 0.5 3.1 3 1 0 3 3 3 2 2-enoyl-CoA Hydratase C-terminal region F-box-like PF12937.2 OAJ23449.1 - 1.5e-07 31.0 0.5 9e-07 28.5 0.5 2.4 2 0 0 2 2 2 1 F-box-like TPR_11 PF13414.1 OAJ23449.1 - 0.012 15.2 1.2 0.049 13.2 0.5 2.1 1 1 2 3 3 3 0 TPR repeat F-box PF00646.28 OAJ23449.1 - 0.013 15.1 0.6 0.048 13.3 0.4 2.0 1 1 0 1 1 1 0 F-box domain Urb2 PF10441.4 OAJ23450.1 - 8.5e-30 104.0 0.0 6e-29 101.2 0.0 2.7 2 0 0 2 2 2 1 Urb2/Npa2 family Peptidase_S8 PF00082.17 OAJ23451.1 - 4.7e-49 167.0 0.1 7e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 OAJ23451.1 - 3.5e-05 23.4 0.0 0.00013 21.6 0.0 2.0 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 OAJ23451.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Fn3-like domain (DUF1034) DUF1279 PF06916.8 OAJ23452.1 - 4e-16 59.0 0.3 4.6e-15 55.7 0.2 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Sld5 PF05916.6 OAJ23453.1 - 0.0045 17.2 0.0 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Peptidase_M17 PF00883.16 OAJ23453.1 - 0.12 11.1 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 Cytosol aminopeptidase family, catalytic domain DMRL_synthase PF00885.14 OAJ23454.1 - 4.6e-43 146.3 0.0 7.1e-24 84.1 0.0 2.1 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase BaffR-Tall_bind PF09256.5 OAJ23454.1 - 0.051 13.1 0.1 0.051 13.1 0.0 2.0 2 0 0 2 2 2 0 BAFF-R, TALL-1 binding NRDE PF05742.7 OAJ23455.1 - 0.019 14.2 0.0 0.066 12.5 0.0 1.8 1 1 0 1 1 1 0 NRDE protein BCNT PF07572.7 OAJ23456.1 - 1.5e-13 50.4 4.4 8e-08 32.1 1.0 2.2 2 0 0 2 2 2 2 Bucentaur or craniofacial development APC_CDC26 PF10471.4 OAJ23456.1 - 2.3 9.0 6.6 0.34 11.6 1.9 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Na_Ca_ex PF01699.19 OAJ23457.1 - 9.5e-17 60.9 1.5 1.4e-16 60.4 1.0 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein PASTA PF03793.14 OAJ23458.1 - 0.17 11.5 3.4 0.15 11.7 0.6 2.2 2 0 0 2 2 2 0 PASTA domain ATP-synt_DE PF00401.15 OAJ23458.1 - 1.2 9.0 8.8 9 6.2 1.0 3.0 2 1 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Transcrip_reg PF01709.15 OAJ23460.1 - 3.9e-54 183.2 0.0 1.5e-53 181.3 0.0 1.7 1 1 1 2 2 2 1 Transcriptional regulator Spore_III_AB PF09548.5 OAJ23460.1 - 0.01 15.6 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) DnaJ PF00226.26 OAJ23461.1 - 5.1e-15 54.9 1.8 1.1e-14 53.8 1.3 1.6 1 0 0 1 1 1 1 DnaJ domain PGM_PMM_I PF02878.11 OAJ23462.1 - 2.9e-22 78.6 0.1 2.9e-12 46.2 0.1 2.6 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 OAJ23462.1 - 2.4e-10 40.6 0.0 1.2e-09 38.4 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 OAJ23462.1 - 4.5e-09 36.1 0.1 1.2e-08 34.7 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 OAJ23462.1 - 0.00013 21.9 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Alg6_Alg8 PF03155.10 OAJ23463.1 - 1e-114 383.9 9.7 2.5e-79 267.2 3.9 3.0 3 0 0 3 3 3 3 ALG6, ALG8 glycosyltransferase family zf-C2H2_4 PF13894.1 OAJ23466.1 - 1.7e-11 43.5 11.4 0.00067 19.8 0.0 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 OAJ23466.1 - 2.5e-11 43.2 11.4 0.0048 17.1 0.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAJ23466.1 - 7e-10 38.7 13.8 0.0004 20.5 1.8 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 OAJ23466.1 - 0.0043 17.1 9.2 0.13 12.4 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 OAJ23466.1 - 0.013 15.3 1.0 0.59 10.1 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAJ23466.1 - 0.053 13.6 0.2 0.053 13.6 0.1 4.1 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2HC PF01530.13 OAJ23466.1 - 0.077 12.7 4.0 6.1 6.6 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2HC type OSTMP1 PF09777.4 OAJ23466.1 - 0.14 11.3 0.3 0.24 10.5 0.2 1.3 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor zf-C2HC_2 PF13913.1 OAJ23466.1 - 0.22 11.2 0.5 0.48 10.1 0.3 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type DPBB_1 PF03330.13 OAJ23467.1 - 1.4e-08 34.5 0.1 2.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ23467.1 - 0.00024 20.7 0.7 0.00041 20.0 0.5 1.6 1 1 0 1 1 1 1 Barwin family Pro_dh PF01619.13 OAJ23468.1 - 2.3e-33 115.5 0.0 4.1e-17 62.1 0.0 3.3 2 1 0 2 2 2 2 Proline dehydrogenase SET PF00856.23 OAJ23469.1 - 6.1e-22 78.6 0.0 5.2e-21 75.6 0.0 2.3 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 OAJ23469.1 - 1.1e-05 25.6 2.6 2.4e-05 24.5 1.8 1.6 1 0 0 1 1 1 1 Pre-SET motif PPR_2 PF13041.1 OAJ23471.1 - 9.2e-17 60.7 0.0 0.00057 19.8 0.0 4.6 4 0 0 4 4 4 4 PPR repeat family PPR_3 PF13812.1 OAJ23471.1 - 1.6e-09 37.2 2.7 0.22 11.8 0.0 6.6 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR PF01535.15 OAJ23471.1 - 4.9e-07 29.3 2.5 0.22 11.5 0.1 5.2 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.2 OAJ23471.1 - 0.00016 21.0 0.2 1.5 8.3 0.0 4.0 4 0 0 4 4 4 2 PPR repeat SelB-wing_2 PF09106.6 OAJ23471.1 - 0.033 14.1 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Na_H_Exchanger PF00999.16 OAJ23472.1 - 1e-64 218.4 35.6 1.4e-64 218.0 24.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4366 PF14283.1 OAJ23472.1 - 0.03 13.7 0.0 4.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Pex16 PF08610.5 OAJ23473.1 - 1.3e-75 254.5 0.1 2.6e-58 197.6 0.0 3.1 2 1 0 2 2 2 2 Peroxisomal membrane protein (Pex16) DUF2431 PF10354.4 OAJ23474.1 - 6.9e-31 107.4 0.0 1.9e-28 99.5 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) CN_hydrolase PF00795.17 OAJ23475.1 - 4.1e-19 68.6 0.0 1.6e-17 63.4 0.0 2.2 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase YlbD_coat PF14071.1 OAJ23475.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative coat protein RVT_1 PF00078.22 OAJ23476.1 - 6.6e-11 41.9 0.0 1.3e-09 37.7 0.0 2.2 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ23476.1 - 0.0017 17.9 0.0 0.0041 16.7 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase LTV PF04180.9 OAJ23478.1 - 2.2e-46 159.2 32.7 3.2e-46 158.6 13.5 2.6 2 1 0 2 2 2 2 Low temperature viability protein Peptidase_C8 PF03569.8 OAJ23478.1 - 0.092 12.0 0.7 0.21 10.8 0.5 1.6 1 0 0 1 1 1 0 Peptidase family C8 YjgP_YjgQ PF03739.9 OAJ23479.1 - 3 6.4 4.2 5.8 5.5 2.9 1.5 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family RTC PF01137.16 OAJ23480.1 - 1.7e-57 193.8 0.0 2.2e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 OAJ23480.1 - 6.4e-29 99.9 0.0 1.2e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain MarR_2 PF12802.2 OAJ23480.1 - 0.1 12.3 0.2 19 5.0 0.0 2.9 2 0 0 2 2 2 0 MarR family IL13 PF03487.8 OAJ23480.1 - 0.12 12.1 0.1 0.36 10.5 0.1 1.9 1 0 0 1 1 1 0 Interleukin-13 Zn_clus PF00172.13 OAJ23481.1 - 0.00035 20.4 15.1 0.0005 19.9 10.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM220 PF15487.1 OAJ23482.1 - 0.76 9.0 9.9 1.8 7.8 6.9 1.7 1 0 0 1 1 1 0 FAM220 family KAAG1 PF15354.1 OAJ23486.1 - 1.5 9.1 4.1 1.7 9.0 2.9 1.2 1 0 0 1 1 1 0 Kidney-associated antigen 1 TPR_11 PF13414.1 OAJ23487.1 - 2e-18 65.7 1.7 5.2e-15 54.8 0.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 OAJ23487.1 - 1.1e-13 50.1 1.0 0.0015 18.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ23487.1 - 2.9e-11 42.3 1.3 0.0062 16.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ23487.1 - 2.6e-06 27.6 0.1 0.001 19.3 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ23487.1 - 4e-06 26.8 0.4 5.9e-06 26.3 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 OAJ23487.1 - 9.8e-05 22.9 1.0 0.22 12.2 0.0 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ23487.1 - 0.0024 18.3 1.6 0.59 10.9 1.5 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ23487.1 - 0.0029 17.6 0.6 0.66 10.3 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ23487.1 - 0.003 17.2 0.3 0.75 9.7 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ23487.1 - 0.0031 17.3 0.5 0.41 10.6 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat HHH_8 PF14716.1 OAJ23487.1 - 0.025 14.7 0.3 4.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain TPR_6 PF13174.1 OAJ23487.1 - 0.16 12.4 1.6 23 5.7 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat SSF PF00474.12 OAJ23488.1 - 1.1e-12 47.3 25.3 4.5e-12 45.3 17.6 2.0 1 1 0 1 1 1 1 Sodium:solute symporter family Sod_Fe_C PF02777.13 OAJ23490.1 - 1.1e-34 118.4 0.7 1.9e-34 117.6 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 OAJ23490.1 - 5.1e-32 109.9 5.1 1.1e-31 108.9 3.6 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AsmA_1 PF13109.1 OAJ23490.1 - 0.0038 16.5 0.1 0.037 13.2 0.0 2.2 1 1 2 3 3 3 1 AsmA-like C-terminal region Ribosomal_S19 PF00203.16 OAJ23491.1 - 3.5e-24 84.2 0.0 4.4e-24 83.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 DUF1242 PF06842.7 OAJ23492.1 - 3.6e-18 64.7 2.1 4.8e-18 64.3 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Jag_N PF14804.1 OAJ23492.1 - 0.076 13.0 0.3 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 Jag N-terminus LSR PF05624.9 OAJ23492.1 - 0.53 10.0 3.0 0.22 11.3 0.5 1.6 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) RPN7 PF10602.4 OAJ23493.1 - 2.9e-43 147.2 0.0 1.4e-42 145.1 0.0 2.1 2 1 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 OAJ23493.1 - 4e-13 49.6 0.0 8.3e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 PCI domain EAP30 PF04157.11 OAJ23493.1 - 0.041 13.0 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family HORMA PF02301.13 OAJ23494.1 - 1.1e-18 67.4 0.0 1.3e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 HORMA domain Vps54 PF07928.7 OAJ23495.1 - 7.1e-53 178.3 1.5 1.8e-52 177.0 1.1 1.7 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 OAJ23495.1 - 2e-05 23.6 2.6 2e-05 23.6 1.8 2.1 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Inhibitor_I71 PF12628.2 OAJ23495.1 - 1.9 8.1 6.4 70 3.0 0.0 2.6 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor SET PF00856.23 OAJ23496.1 - 1.2e-25 90.6 0.2 8.4e-25 87.9 0.0 2.6 2 0 0 2 2 2 1 SET domain N-SET PF11764.3 OAJ23496.1 - 1.4e-14 54.3 0.3 1.4e-14 54.3 0.2 2.8 2 1 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N BUD22 PF09073.5 OAJ23496.1 - 0.0067 15.5 18.2 0.031 13.3 12.6 2.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.7 OAJ23496.1 - 0.63 7.9 17.9 1.1 7.1 12.4 1.3 1 0 0 1 1 1 0 Nop14-like family DDE_Tnp_2 PF04693.7 OAJ23496.1 - 1.1 8.2 0.0 1.6 7.6 0.0 1.1 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 Ebola_NP PF05505.7 OAJ23496.1 - 2.7 5.9 14.2 5 5.0 9.8 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein UCH PF00443.24 OAJ23497.1 - 1.3e-38 132.7 0.0 7e-38 130.2 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ23497.1 - 1.8e-08 34.1 0.0 0.049 13.0 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase PAT1 PF09770.4 OAJ23498.1 - 0.01 14.1 21.3 0.014 13.6 14.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ProRS-C_1 PF09180.6 OAJ23499.1 - 3.3e-25 87.7 1.8 7.1e-25 86.7 1.2 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 OAJ23499.1 - 2.1e-23 82.8 0.0 6.5e-23 81.1 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ23499.1 - 8.2e-16 57.7 0.0 1.7e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain TraC_F_IV PF11130.3 OAJ23499.1 - 0.051 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer ChAPs PF09295.5 OAJ23500.1 - 6.3e-152 505.9 0.0 1.4e-151 504.8 0.0 1.5 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) Apc3 PF12895.2 OAJ23500.1 - 0.00014 21.8 0.2 0.13 12.4 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 OAJ23500.1 - 0.00027 21.1 0.0 0.19 12.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ23500.1 - 0.012 15.2 7.0 0.032 13.8 0.0 3.7 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.12 OAJ23500.1 - 0.012 15.4 0.3 4.9 7.3 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat AMP-binding PF00501.23 OAJ23501.1 - 3.8e-90 302.2 0.0 4.7e-90 301.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ23501.1 - 2.5e-09 37.9 0.2 7.3e-09 36.4 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Menin PF05053.8 OAJ23501.1 - 4.4 5.3 5.8 6.4 4.8 4.0 1.1 1 0 0 1 1 1 0 Menin SNF2_N PF00176.18 OAJ23502.1 - 7.8e-66 221.8 0.2 1.1e-65 221.4 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ23502.1 - 3.9e-14 52.2 0.0 1.1e-13 50.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ23502.1 - 1.1e-06 28.6 0.0 3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ23502.1 - 1.1e-05 25.0 0.0 2.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase UBA PF00627.26 OAJ23502.1 - 3.1e-05 23.6 0.1 8.6e-05 22.2 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Pkinase PF00069.20 OAJ23503.1 - 1.1e-64 218.0 0.0 1.6e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ23503.1 - 8.6e-29 100.3 0.0 1.1e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ23503.1 - 4.8e-07 29.0 0.0 8.7e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ23503.1 - 0.045 13.4 0.0 1.7 8.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ23503.1 - 0.063 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 TFIIA PF03153.8 OAJ23503.1 - 2.6 7.8 7.6 3.5 7.4 5.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.3 OAJ23503.1 - 8.7 5.4 20.5 14 4.8 14.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Lambda_tail_I PF06805.7 OAJ23511.1 - 0.13 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I PIF1 PF05970.9 OAJ23512.1 - 5.1e-20 71.7 0.0 7.4e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ23512.1 - 3.6e-10 39.7 0.0 1.1e-09 38.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ23512.1 - 1.2e-07 31.3 0.1 4.8e-07 29.4 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 OAJ23512.1 - 0.00044 20.2 0.3 0.0015 18.5 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 OAJ23512.1 - 0.0038 16.8 1.0 1.8 8.0 0.1 2.7 2 1 1 3 3 3 2 AAA domain Torsin PF06309.6 OAJ23512.1 - 0.0059 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Torsin AAA_22 PF13401.1 OAJ23512.1 - 0.013 15.6 0.0 0.035 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 OAJ23512.1 - 0.014 14.8 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 OAJ23512.1 - 0.046 13.3 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 OAJ23512.1 - 0.047 13.7 0.0 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ23512.1 - 0.053 13.2 0.1 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 OAJ23512.1 - 0.063 13.4 0.0 0.18 12.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 OAJ23512.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TPR_11 PF13414.1 OAJ23513.1 - 1.5e-24 85.4 16.0 4.8e-12 45.3 0.1 3.5 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 OAJ23513.1 - 3.6e-22 76.9 0.5 5e-08 32.2 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ23513.1 - 1.9e-21 74.2 7.3 3.8e-06 26.4 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ23513.1 - 8.8e-15 53.8 6.8 0.00041 20.7 0.1 5.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ23513.1 - 1.9e-12 47.4 6.5 5.6e-08 33.2 0.2 4.8 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ23513.1 - 8e-12 44.3 2.5 0.00013 21.9 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ23513.1 - 1.3e-11 43.3 0.0 0.039 13.7 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ23513.1 - 1.5e-10 41.2 2.7 0.0048 17.2 0.2 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ23513.1 - 1.4e-09 37.7 10.6 1.8e-05 24.5 1.2 4.1 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ23513.1 - 5.8e-08 31.9 1.9 0.017 14.9 0.0 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ23513.1 - 5.5e-05 23.3 8.3 5.6 7.6 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ23513.1 - 0.00043 20.3 5.5 0.26 11.4 0.1 3.8 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ23513.1 - 0.0013 18.6 6.7 0.89 9.5 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ23513.1 - 0.0024 17.9 3.9 0.0045 17.0 0.4 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 OAJ23513.1 - 0.0098 14.9 3.3 1.2 8.1 0.7 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.12 OAJ23513.1 - 0.057 13.7 12.9 0.61 10.3 1.3 4.0 3 1 1 4 4 4 0 Bacterial transcriptional activator domain TPR_3 PF07720.7 OAJ23513.1 - 0.072 12.9 0.5 2.4 8.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ23513.1 - 0.34 10.7 8.3 0.33 10.8 0.7 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4407 PF14362.1 OAJ23513.1 - 6.7 5.5 13.8 0.31 9.9 0.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) FUSC PF04632.7 OAJ23514.1 - 0.083 11.3 0.0 0.088 11.2 0.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cyclin_N PF00134.18 OAJ23515.1 - 3.8e-09 36.1 0.0 7.1e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 OAJ23515.1 - 4e-07 30.5 1.1 9.3e-07 29.3 0.0 2.2 2 2 0 2 2 2 1 Cyclin Ribosomal_60s PF00428.14 OAJ23515.1 - 2.4 8.6 12.5 7.5 7.0 8.7 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-CCCH_2 PF14608.1 OAJ23516.1 - 0.065 13.2 33.0 1.9 8.5 0.5 5.4 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type OSCP PF00213.13 OAJ23517.1 - 1.1e-38 132.8 0.6 1.3e-38 132.5 0.4 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Nuc_sug_transp PF04142.10 OAJ23518.1 - 6.1e-52 176.1 0.7 1.3e-36 125.9 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 OAJ23518.1 - 6.4e-05 23.1 4.2 6.4e-05 23.1 2.9 2.7 2 2 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 OAJ23518.1 - 0.00063 19.7 6.2 0.00063 19.7 4.3 3.1 2 2 1 3 3 3 1 EamA-like transporter family DUF3439 PF11921.3 OAJ23518.1 - 0.0077 15.9 0.1 0.024 14.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) TPT PF03151.11 OAJ23518.1 - 0.14 11.7 12.8 0.016 14.8 2.9 3.1 3 1 0 4 4 4 0 Triose-phosphate Transporter family TPR_2 PF07719.12 OAJ23520.1 - 0.00043 20.0 0.2 5.3 7.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ23520.1 - 0.00052 19.9 2.8 0.0032 17.3 0.1 3.3 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ23520.1 - 0.0037 17.1 10.0 0.026 14.4 0.3 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat RHH_4 PF13467.1 OAJ23520.1 - 0.018 14.9 0.3 0.086 12.7 0.1 2.4 2 1 0 2 2 2 0 Ribbon-helix-helix domain TPR_11 PF13414.1 OAJ23520.1 - 0.024 14.2 0.5 0.18 11.4 0.1 2.6 3 1 0 3 3 3 0 TPR repeat Muted PF14942.1 OAJ23520.1 - 0.1 12.4 2.3 0.12 12.2 0.8 1.8 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Apc5 PF12862.2 OAJ23520.1 - 0.11 12.3 4.0 8.1 6.3 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 Toxin_39 PF15500.1 OAJ23520.1 - 0.54 10.4 2.2 2.2 8.4 0.3 2.3 2 0 0 2 2 2 0 Putative RNase-like toxin TPR_16 PF13432.1 OAJ23520.1 - 1.1 10.0 5.1 7.9 7.2 0.1 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat GST_C_4 PF14834.1 OAJ23521.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Apolipoprotein PF01442.13 OAJ23522.1 - 2.8e-06 27.0 7.7 3.4e-06 26.7 5.4 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Prominin PF05478.6 OAJ23522.1 - 0.0042 14.6 1.2 0.0051 14.4 0.8 1.2 1 0 0 1 1 1 1 Prominin DUF1664 PF07889.7 OAJ23522.1 - 0.019 14.7 3.5 0.23 11.2 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Histidinol_dh PF00815.15 OAJ23522.1 - 0.056 12.0 0.2 0.068 11.7 0.1 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase Baculo_PEP_C PF04513.7 OAJ23522.1 - 0.059 13.1 5.4 0.24 11.2 3.0 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2317 PF10079.4 OAJ23522.1 - 0.087 11.4 3.1 0.12 10.9 2.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Fzo_mitofusin PF04799.8 OAJ23522.1 - 0.099 12.0 7.8 0.44 9.9 4.7 2.1 1 1 1 2 2 2 0 fzo-like conserved region CENP-F_leu_zip PF10473.4 OAJ23522.1 - 0.16 11.8 6.4 0.66 9.8 1.3 3.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF842 PF05811.8 OAJ23522.1 - 0.23 10.9 3.8 0.31 10.4 2.5 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) ApoLp-III PF07464.6 OAJ23522.1 - 0.31 11.0 5.3 1.4 8.8 3.4 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Muted PF14942.1 OAJ23522.1 - 0.38 10.6 6.9 0.78 9.6 2.2 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein MxiH PF09392.5 OAJ23522.1 - 1.2 9.7 6.9 0.85 10.2 2.8 2.3 2 1 0 2 2 2 0 Type III secretion needle MxiH like DUF883 PF05957.8 OAJ23522.1 - 2.1 8.8 7.2 3 8.2 3.0 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) OmpH PF03938.9 OAJ23522.1 - 2.6 7.9 7.8 2.5 8.0 4.6 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Histone PF00125.19 OAJ23524.1 - 5.9e-09 35.9 0.1 7.9e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ23524.1 - 0.00081 19.5 0.1 0.0014 18.7 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 OAJ23524.1 - 0.0016 18.3 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T PF15511.1 OAJ23524.1 - 0.024 13.8 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PCP_red PF08369.5 OAJ23524.1 - 0.03 14.2 0.8 3.1 7.7 0.1 2.7 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Bromo_TP PF07524.8 OAJ23524.1 - 0.083 12.6 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF4095 PF13338.1 OAJ23524.1 - 0.11 12.7 0.2 0.15 12.1 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4095) DUF2730 PF10805.3 OAJ23525.1 - 0.069 12.8 0.8 0.13 12.0 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) PALP PF00291.20 OAJ23526.1 - 8.1e-63 212.4 0.1 8.1e-63 212.4 0.1 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Telomere_Sde2_2 PF13297.1 OAJ23526.1 - 0.13 11.5 0.2 4.8 6.5 0.0 2.9 3 0 0 3 3 3 0 Telomere stability C-terminal ATG13 PF10033.4 OAJ23527.1 - 1.2e-26 93.5 0.0 2e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 TBCC PF07986.7 OAJ23530.1 - 7.9e-15 54.3 2.1 7e-14 51.2 0.9 2.2 2 0 0 2 2 2 1 Tubulin binding cofactor C F_actin_bind PF08919.5 OAJ23530.1 - 0.84 9.3 3.5 3.9 7.2 0.4 3.1 1 1 2 3 3 3 0 F-actin binding WD40 PF00400.27 OAJ23531.1 - 3.8e-19 67.7 25.3 1.1e-07 31.4 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 OAJ23531.1 - 1.6e-14 53.6 0.0 2.8e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain PBP1_TM PF14812.1 OAJ23531.1 - 0.49 10.7 3.4 0.83 9.9 2.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal E1-E2_ATPase PF00122.15 OAJ23532.1 - 1.4e-22 79.8 0.0 5.7e-22 77.8 0.0 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 OAJ23532.1 - 2.2e-18 67.4 0.0 1.1e-17 65.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAJ23532.1 - 1.3e-11 45.0 0.1 3.8e-11 43.5 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ23532.1 - 4.2e-06 26.6 0.0 1.3e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAJ23532.1 - 0.0014 18.2 0.2 0.0038 16.8 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_S6 PF01250.12 OAJ23533.1 - 5.4e-14 51.8 0.0 6.7e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 WD40 PF00400.27 OAJ23534.1 - 6.7e-10 38.4 4.9 3e-05 23.7 0.0 6.0 7 0 0 7 7 7 2 WD domain, G-beta repeat eIF2A PF08662.6 OAJ23534.1 - 0.0033 17.1 0.0 4 7.0 0.0 3.8 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 OAJ23534.1 - 0.013 15.1 2.2 2.3 7.9 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 OAJ23534.1 - 0.024 14.3 1.0 7.3 6.2 0.0 3.5 4 0 0 4 4 4 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 OAJ23534.1 - 0.2 9.4 0.0 1.9 6.1 0.0 2.2 2 0 0 2 2 2 0 IKI3 family His_Phos_1 PF00300.17 OAJ23535.1 - 0.0037 17.3 0.0 0.004 17.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Lipase_GDSL_2 PF13472.1 OAJ23536.1 - 1.6e-25 90.3 0.0 1.9e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 OAJ23536.1 - 1.3e-22 80.7 0.0 3.9e-22 79.2 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CHORD PF04968.7 OAJ23537.1 - 2.7e-42 142.8 14.4 2.7e-23 81.9 2.0 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 OAJ23537.1 - 7.4e-09 36.0 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 CS domain BTK PF00779.14 OAJ23537.1 - 0.84 9.3 10.2 0.21 11.2 0.8 2.8 2 1 0 2 2 2 0 BTK motif XdhC_CoxI PF02625.11 OAJ23538.1 - 0.046 13.3 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 XdhC and CoxI family LcrG PF07216.7 OAJ23538.1 - 3.6 7.6 7.4 0.81 9.7 2.0 1.9 1 1 1 2 2 2 0 LcrG protein UQ_con PF00179.21 OAJ23540.1 - 1.2e-20 73.3 0.0 2.1e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 OAJ23540.1 - 0.019 14.8 0.0 0.049 13.5 0.0 1.7 1 0 0 1 1 1 0 RWD domain zf-4CXXC_R1 PF10497.4 OAJ23540.1 - 0.038 14.1 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Acetyltransf_1 PF00583.19 OAJ23544.1 - 6.6e-15 54.9 0.0 1.1e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ23544.1 - 2.6e-12 46.7 0.0 3.9e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAJ23544.1 - 5.2e-07 29.8 0.0 6.6e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 OAJ23544.1 - 1e-05 25.7 0.0 1.4e-05 25.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAJ23544.1 - 5.4e-05 23.0 0.0 7.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ23544.1 - 0.00024 20.8 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 OAJ23544.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Mastoparan_2 PF08251.6 OAJ23544.1 - 3.8 7.7 4.5 1 9.5 0.4 2.1 2 0 0 2 2 2 0 Mastoparan peptide CLTH PF10607.4 OAJ23546.1 - 1.5e-20 73.3 0.0 2.4e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 OAJ23546.1 - 0.013 15.2 0.2 0.035 13.8 0.2 1.8 1 0 0 1 1 1 0 LisH FA_hydroxylase PF04116.8 OAJ23549.1 - 5.2e-15 55.8 16.5 5.2e-15 55.8 11.4 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2013 PF09431.5 OAJ23550.1 - 1e-49 167.9 2.0 1.9e-49 167.0 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) RRM_1 PF00076.17 OAJ23551.1 - 1.2e-34 117.7 0.0 4.9e-20 70.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ23551.1 - 1.9e-30 104.6 0.0 2.8e-15 56.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ23551.1 - 1.3e-22 79.3 0.0 3.9e-08 33.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 OAJ23551.1 - 4.4e-14 52.5 0.1 1e-13 51.3 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 OAJ23551.1 - 0.00015 21.5 0.0 0.00056 19.7 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 OAJ23551.1 - 0.0077 15.9 0.0 0.75 9.6 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif TEA PF01285.13 OAJ23552.1 - 1.8e-31 109.8 0.0 8.5e-31 107.5 0.0 2.1 1 1 0 1 1 1 1 TEA/ATTS domain family NBP1 PF08537.5 OAJ23552.1 - 0.39 9.8 3.2 0.75 8.9 2.2 1.4 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Ribonucleas_3_3 PF14622.1 OAJ23555.1 - 3.4e-20 72.2 0.9 4.6e-20 71.8 0.0 1.6 2 0 0 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 OAJ23555.1 - 0.098 13.1 0.1 2.3 8.6 0.0 2.5 2 1 0 2 2 2 0 Ribonuclease III domain Brevenin PF03032.10 OAJ23555.1 - 0.28 11.0 0.9 0.57 10.0 0.0 1.8 2 0 0 2 2 2 0 Brevenin/esculentin/gaegurin/rugosin family Helicase_RecD PF05127.9 OAJ23555.1 - 0.76 9.3 3.9 1.5 8.4 2.7 1.5 1 0 0 1 1 1 0 Helicase PAT1 PF09770.4 OAJ23555.1 - 1.6 6.8 24.6 2.1 6.5 17.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 OAJ23555.1 - 2.3 8.0 12.0 3.1 7.6 8.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.10 OAJ23555.1 - 4.3 6.5 8.7 5.7 6.1 6.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF605 PF04652.11 OAJ23555.1 - 9 5.5 17.4 13 5.0 12.1 1.2 1 0 0 1 1 1 0 Vta1 like Catalase PF00199.14 OAJ23556.1 - 2.1e-160 533.6 1.0 2.5e-160 533.3 0.7 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 OAJ23556.1 - 3e-15 55.8 0.1 8.9e-15 54.3 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive DAO PF01266.19 OAJ23557.1 - 6e-42 143.8 0.6 7.7e-41 140.1 0.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ23557.1 - 0.0003 20.7 0.1 0.0012 18.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAJ23557.1 - 0.041 14.2 0.0 0.97 9.8 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ23557.1 - 0.073 12.9 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ATP13 PF12921.2 OAJ23557.1 - 0.1 11.9 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ATPase expression Shikimate_DH PF01488.15 OAJ23557.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 OAJ23557.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Mqo PF06039.10 OAJ23557.1 - 0.22 9.6 0.0 0.31 9.1 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) PCI PF01399.22 OAJ23558.1 - 6e-13 49.0 0.0 1.5e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 PCI domain SSP160 PF06933.6 OAJ23558.1 - 0.027 12.4 2.6 0.036 12.0 1.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FHA PF00498.21 OAJ23560.1 - 8.9e-15 54.5 0.0 1.9e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain UBA_4 PF14555.1 OAJ23561.1 - 1.4e-08 34.0 0.2 2.2e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 UBA-like domain UIM PF02809.15 OAJ23561.1 - 0.0082 15.6 9.3 0.48 10.1 1.0 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif UBA PF00627.26 OAJ23561.1 - 0.032 14.0 0.0 0.095 12.5 0.0 1.8 2 0 0 2 2 2 0 UBA/TS-N domain Ribosomal_S17 PF00366.15 OAJ23562.1 - 1.8e-16 59.9 0.2 2.6e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 DUF3357 PF11837.3 OAJ23563.1 - 2.9 7.7 7.7 2.2 8.1 0.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3357) DUF3506 PF12014.3 OAJ23564.1 - 5.3e-11 42.4 0.0 1.7e-10 40.8 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 OAJ23564.1 - 0.00057 19.5 0.0 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ23564.1 - 0.02 14.5 0.0 0.051 13.2 0.0 1.7 1 0 0 1 1 1 0 F-box domain HHH_8 PF14716.1 OAJ23564.1 - 0.036 14.2 0.2 0.078 13.1 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Mito_carr PF00153.22 OAJ23565.1 - 5.8e-64 211.8 4.2 5.6e-24 83.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 OAJ23565.1 - 9.4 6.2 8.9 3.4 7.7 0.2 3.3 3 2 1 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family Ras PF00071.17 OAJ23566.1 - 2.4e-50 170.0 0.0 3.3e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ23566.1 - 3.3e-17 63.0 0.0 4.6e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ23566.1 - 9.7e-06 24.9 0.0 1.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 OAJ23566.1 - 0.12 11.8 0.0 5.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF4349 PF14257.1 OAJ23566.1 - 0.14 11.3 3.5 0.19 10.8 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) SRPRB PF09439.5 OAJ23566.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CTP_transf_2 PF01467.21 OAJ23567.1 - 3.6e-14 53.0 0.0 6.1e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase DUF2457 PF10446.4 OAJ23567.1 - 0.0002 20.2 9.8 0.00036 19.3 6.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) YL1 PF05764.8 OAJ23567.1 - 0.002 17.7 7.2 0.0034 17.0 5.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Daxx PF03344.10 OAJ23567.1 - 0.014 13.8 16.7 0.026 13.0 11.6 1.3 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 OAJ23567.1 - 1.1 8.4 12.4 1.9 7.6 8.6 1.3 1 0 0 1 1 1 0 SDA1 Nucleoplasmin PF03066.10 OAJ23567.1 - 1.3 8.5 14.8 2.7 7.4 10.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 OAJ23567.1 - 7.9 5.6 13.0 15 4.7 9.0 1.4 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.8 OAJ23568.1 - 1.7 8.2 4.7 3.6 7.1 2.6 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region ALO PF04030.9 OAJ23569.1 - 5.8e-61 206.3 0.1 1.8e-52 178.5 0.0 2.5 3 0 0 3 3 3 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 OAJ23569.1 - 9.4e-18 64.0 0.0 9.4e-18 64.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain HC2 PF07382.6 OAJ23573.1 - 6.4e-14 52.2 73.3 3e-13 50.0 32.0 9.9 3 3 5 9 9 9 5 Histone H1-like nucleoprotein HC2 Mem_trans PF03547.13 OAJ23573.1 - 4.5 5.4 8.0 7.3 4.7 5.6 1.3 1 0 0 1 1 1 0 Membrane transport protein NMT PF01233.14 OAJ23574.1 - 2.5e-75 251.5 0.0 4.1e-75 250.8 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 OAJ23574.1 - 1.7e-62 210.1 0.0 6.5e-62 208.2 0.0 1.9 2 1 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 OAJ23574.1 - 0.0027 17.5 0.0 0.0084 15.9 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAJ23574.1 - 0.059 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAJ23574.1 - 0.099 12.6 0.1 2.6 8.1 0.0 2.8 2 1 1 3 3 3 0 Acetyltransferase (GNAT) family IMS PF00817.15 OAJ23575.1 - 1.8e-28 99.2 0.0 3.4e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.3 OAJ23575.1 - 0.0086 16.0 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Nuf2 PF03800.9 OAJ23575.1 - 0.22 11.5 0.0 0.47 10.4 0.0 1.5 1 0 0 1 1 1 0 Nuf2 family Ank_2 PF12796.2 OAJ23576.1 - 3.5e-18 65.7 0.0 2.3e-11 43.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ23576.1 - 1.6e-10 41.1 0.0 2.1e-05 24.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ23576.1 - 5.3e-10 39.2 0.4 0.018 15.2 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 OAJ23576.1 - 8.7e-07 28.4 0.0 1.9 8.4 0.1 4.7 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 OAJ23576.1 - 6.2e-05 22.8 1.6 0.13 12.5 0.1 4.1 4 1 0 4 4 4 2 Ankyrin repeat HSCB_C PF07743.8 OAJ23577.1 - 1.8e-14 53.9 0.7 1.8e-14 53.9 0.5 1.6 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 OAJ23577.1 - 8e-10 38.3 0.0 1.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain cwf21 PF08312.7 OAJ23577.1 - 0.0045 16.8 1.4 0.011 15.5 0.9 1.6 1 0 0 1 1 1 1 cwf21 domain EF-hand_1 PF00036.27 OAJ23578.1 - 8.2e-28 93.5 13.7 8.5e-08 30.9 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 OAJ23578.1 - 1.5e-23 82.6 4.7 9.1e-12 44.9 1.5 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 OAJ23578.1 - 2.1e-21 73.8 8.4 3e-05 23.5 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 OAJ23578.1 - 7.6e-20 69.3 15.2 4.8e-06 25.6 1.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 OAJ23578.1 - 3e-14 52.3 16.4 0.00021 20.8 1.8 4.5 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 OAJ23578.1 - 2.2e-05 24.4 0.0 0.007 16.3 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 OAJ23578.1 - 0.00019 21.1 6.7 0.0077 15.9 0.6 3.6 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 OAJ23578.1 - 0.00063 19.6 0.0 0.37 10.7 0.1 3.1 2 1 1 3 3 3 1 EF-hand domain VCBS PF13517.1 OAJ23578.1 - 0.079 13.3 1.2 7.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RTA1 PF04479.8 OAJ23579.1 - 2.3e-29 102.5 7.0 2.3e-29 102.5 4.9 1.6 2 0 0 2 2 2 1 RTA1 like protein Cation_ATPase_C PF00689.16 OAJ23579.1 - 0.0061 16.1 9.9 0.4 10.1 6.9 2.3 1 1 0 1 1 1 1 Cation transporting ATPase, C-terminus ABC2_membrane_5 PF13346.1 OAJ23579.1 - 3.4 6.9 14.2 4.5 6.5 3.4 2.4 2 1 0 2 2 2 0 ABC-2 family transporter protein SelR PF01641.13 OAJ23580.1 - 3.2e-50 168.9 0.0 4.3e-50 168.5 0.0 1.2 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.1 OAJ23580.1 - 0.051 13.4 2.2 0.12 12.2 0.2 2.5 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Dicty_REP PF05086.7 OAJ23580.1 - 1.2 6.7 2.7 1.4 6.5 1.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Prenyltransf PF01255.14 OAJ23582.1 - 4.6e-75 251.5 0.0 5.8e-75 251.2 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Rer1 PF03248.8 OAJ23582.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Rer1 family Cmc1 PF08583.5 OAJ23583.1 - 0.063 13.0 1.5 0.33 10.7 1.4 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 OAJ23583.1 - 0.12 12.2 0.5 0.32 10.8 0.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) COX17 PF05051.8 OAJ23583.1 - 0.16 12.0 1.1 0.31 11.0 0.8 1.5 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) SET PF00856.23 OAJ23584.1 - 0.0055 17.0 0.0 0.024 14.9 0.0 1.9 1 1 0 1 1 1 1 SET domain DUF605 PF04652.11 OAJ23584.1 - 0.2 11.0 4.5 0.19 11.1 3.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF3827 PF12877.2 OAJ23584.1 - 0.26 9.3 1.1 0.35 8.9 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Gag_spuma PF03276.9 OAJ23584.1 - 4.4 5.5 8.4 5 5.3 5.8 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Rhodanese PF00581.15 OAJ23585.1 - 2.8e-16 59.8 0.0 4.5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain P19Arf_N PF07392.7 OAJ23585.1 - 0.054 13.6 0.4 0.19 11.8 0.3 1.9 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus Suf PF05843.9 OAJ23586.1 - 1.7 8.3 4.8 2.1 7.9 3.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 OAJ23586.1 - 2.1 6.4 27.1 2.3 6.3 18.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 OAJ23586.1 - 6.5 6.0 29.2 8.1 5.7 20.3 1.2 1 0 0 1 1 1 0 Vta1 like MFS_1 PF07690.11 OAJ23587.1 - 4.2e-29 101.3 25.8 4.2e-29 101.3 17.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ23587.1 - 1e-21 77.1 19.0 4.1e-19 68.4 4.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Myc_target_1 PF15179.1 OAJ23587.1 - 0.57 9.7 1.5 1.5 8.4 1.1 1.6 1 0 0 1 1 1 0 Myc target protein 1 Ribosomal_S13 PF00416.17 OAJ23588.1 - 2.8e-24 85.6 0.0 3.6e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 OAJ23588.1 - 0.0014 17.3 0.0 0.0017 16.9 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) FAM70 PF14967.1 OAJ23588.1 - 3.4 6.7 5.3 4.5 6.3 3.7 1.1 1 0 0 1 1 1 0 FAM70 protein Herpes_capsid PF06112.6 OAJ23588.1 - 3.6 7.6 7.7 2.4 8.1 2.7 2.0 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Abhydrolase_3 PF07859.8 OAJ23589.1 - 2.1e-15 56.8 0.0 4.6e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ23589.1 - 3.9e-09 36.4 0.0 1.2e-08 34.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ23589.1 - 9.3e-07 28.2 0.0 2e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.23 OAJ23589.1 - 0.01 14.6 0.0 0.019 13.6 0.0 1.4 2 0 0 2 2 2 0 Carboxylesterase family DEC-1_N PF04625.8 OAJ23589.1 - 2.3 6.7 6.9 3.5 6.2 4.8 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PCI_Csn8 PF10075.4 OAJ23590.1 - 1.4e-33 115.7 0.0 1.9e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 OAJ23590.1 - 3.1e-30 105.2 0.0 3.9e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Nup188 PF10487.4 OAJ23591.1 - 0.0013 16.8 0.0 0.065 11.1 0.0 2.6 3 0 0 3 3 3 2 Nucleoporin subcomplex protein binding to Pom34 Rhodanese PF00581.15 OAJ23592.1 - 2e-12 47.4 0.0 5.8e-12 45.9 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain Oxysterol_BP PF01237.13 OAJ23593.1 - 7.7e-23 80.5 0.0 9.4e-23 80.2 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein UL73_N PF12522.3 OAJ23593.1 - 0.22 11.0 3.0 0.24 10.9 1.0 2.0 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein N terminal Proteasome PF00227.21 OAJ23595.1 - 4.7e-40 136.9 0.0 5.4e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Glyco_transf_8 PF01501.15 OAJ23598.1 - 1.3e-28 99.9 0.0 2.9e-25 89.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 OAJ23598.1 - 0.0049 16.2 0.0 0.0081 15.5 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Thiol_cytolysin PF01289.14 OAJ23598.1 - 0.012 13.9 0.0 0.019 13.3 0.0 1.2 1 0 0 1 1 1 0 Thiol-activated cytolysin MFS_1 PF07690.11 OAJ23599.1 - 1.3e-16 60.3 42.7 1.3e-16 60.3 29.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 OAJ23599.1 - 0.024 14.4 1.5 0.097 12.4 1.0 2.1 1 0 0 1 1 1 0 MFS_1 like family HeLo PF14479.1 OAJ23600.1 - 0.0011 18.7 1.8 0.0013 18.5 0.0 1.8 2 0 0 2 2 2 1 Prion-inhibition and propagation DUF3338 PF11819.3 OAJ23600.1 - 5.2 6.5 8.6 0.94 8.9 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3338) DUF2884 PF11101.3 OAJ23601.1 - 0.022 14.1 0.2 0.48 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) BRCT PF00533.21 OAJ23601.1 - 0.046 13.8 0.0 13 6.0 0.0 2.7 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain She9_MDM33 PF05546.6 OAJ23601.1 - 0.1 12.1 0.6 0.28 10.6 0.2 1.7 2 0 0 2 2 2 0 She9 / Mdm33 family Mating_N PF12731.2 OAJ23601.1 - 0.19 11.6 2.5 2 8.3 0.0 2.6 2 0 0 2 2 2 0 Mating-type protein beta 1 Nodulin_late PF07127.6 OAJ23602.1 - 0.17 12.0 2.5 1.8 8.7 0.1 2.6 3 0 0 3 3 3 0 Late nodulin protein Pyridox_oxidase PF01243.15 OAJ23603.1 - 1.5e-11 44.1 0.0 6.4e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DUF374 PF04028.8 OAJ23603.1 - 0.043 13.0 0.1 0.1 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF374) eIF-5_eIF-2B PF01873.12 OAJ23604.1 - 8.1e-45 151.5 0.6 1.3e-44 150.8 0.4 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 OAJ23604.1 - 0.0012 18.1 0.1 0.002 17.4 0.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding MSP1_C PF07462.6 OAJ23604.1 - 0.56 8.5 4.6 1.6 7.0 3.3 1.6 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus PITH PF06201.8 OAJ23605.1 - 2.4e-34 118.3 0.0 3.1e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 PITH domain ATP-synt PF00231.14 OAJ23606.1 - 1.7e-58 198.3 1.5 2e-58 198.0 1.1 1.1 1 0 0 1 1 1 1 ATP synthase Bac_rhamnosid_N PF08531.5 OAJ23606.1 - 0.047 13.2 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain ATP-synt PF00231.14 OAJ23607.1 - 1.8e-10 40.6 6.9 2.2e-10 40.3 4.4 1.3 1 1 0 1 1 1 1 ATP synthase Paf67 PF10255.4 OAJ23607.1 - 0.044 12.6 0.0 0.049 12.5 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 NOP5NT PF08156.8 OAJ23607.1 - 0.13 12.4 0.4 0.27 11.4 0.3 1.6 1 0 0 1 1 1 0 NOP5NT (NUC127) domain DUF3802 PF12290.3 OAJ23607.1 - 0.29 11.4 1.6 18 5.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3802) DUF4404 PF14357.1 OAJ23607.1 - 0.45 10.9 2.1 7.4 7.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Myb_DNA-bind_4 PF13837.1 OAJ23608.1 - 9.1e-05 22.5 1.5 0.0001 22.3 0.1 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.1 OAJ23609.1 - 1.4e-23 83.1 0.0 2.8e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4356 PF14266.1 OAJ23609.1 - 0.0022 16.4 0.1 0.0031 15.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4356) Head-tail_con PF12236.3 OAJ23609.1 - 0.012 14.0 1.0 0.017 13.5 0.7 1.2 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein Trypan_glycop PF00913.14 OAJ23609.1 - 0.14 11.0 4.0 0.19 10.6 2.8 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) LSM PF01423.17 OAJ23610.1 - 2e-15 56.0 0.0 3e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain DUF3510 PF12022.3 OAJ23610.1 - 0.0015 18.5 0.0 0.0019 18.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) GRP PF07172.6 OAJ23610.1 - 2.2 8.8 28.4 3.1 8.3 19.7 1.2 1 0 0 1 1 1 0 Glycine rich protein family CRAL_TRIO PF00650.15 OAJ23611.1 - 3.1e-29 101.5 0.0 4.7e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 OAJ23611.1 - 1.2e-10 41.5 0.0 2.6e-10 40.3 0.0 1.5 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ23611.1 - 8.5e-07 29.0 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Cation_efflux PF01545.16 OAJ23612.1 - 5.6e-27 94.5 0.7 1e-25 90.4 0.2 2.0 2 0 0 2 2 2 2 Cation efflux family Zip PF02535.17 OAJ23612.1 - 0.014 14.4 13.1 0.13 11.2 1.5 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter AAA_17 PF13207.1 OAJ23613.1 - 1.1e-07 32.6 0.1 2.1e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 OAJ23613.1 - 3.8e-07 30.1 0.0 0.00016 21.5 0.0 2.4 2 0 0 2 2 2 2 Shikimate kinase AAA_33 PF13671.1 OAJ23613.1 - 6.8e-06 26.0 0.2 0.025 14.4 0.0 2.5 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 OAJ23613.1 - 7.6e-06 26.2 1.7 0.0039 17.4 0.1 2.6 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAJ23613.1 - 0.00045 19.6 0.4 0.0025 17.2 0.1 2.1 2 1 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 OAJ23613.1 - 0.0015 18.4 0.5 0.026 14.4 0.0 2.6 2 1 1 3 3 3 1 Cytidylate kinase-like family DUF305 PF03713.8 OAJ23613.1 - 0.0066 16.2 1.3 0.014 15.2 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF305) AAA_28 PF13521.1 OAJ23613.1 - 0.021 14.7 1.9 0.036 14.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.15 OAJ23613.1 - 0.087 12.4 0.0 0.21 11.2 0.0 1.6 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_29 PF13555.1 OAJ23613.1 - 0.18 11.3 0.4 0.37 10.3 0.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ23613.1 - 1.3 8.9 4.1 1.2 9.0 0.7 2.2 2 1 0 2 2 2 0 AAA ATPase domain EmrE PF13536.1 OAJ23616.1 - 0.021 15.0 10.7 0.021 15.0 7.4 2.3 3 0 0 3 3 3 0 Multidrug resistance efflux transporter Synaptobrevin PF00957.16 OAJ23616.1 - 0.96 9.0 2.4 2.1 8.0 1.7 1.6 1 0 0 1 1 1 0 Synaptobrevin Exo_endo_phos PF03372.18 OAJ23618.1 - 1.9e-17 64.0 0.5 3e-17 63.3 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Imm1 PF14430.1 OAJ23618.1 - 0.096 12.8 0.0 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Immunity protein Imm1 Cytochrom_D1 PF02239.11 OAJ23618.1 - 0.12 10.6 0.0 0.22 9.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Cutinase PF01083.17 OAJ23619.1 - 4.3e-30 104.7 0.4 5.3e-30 104.4 0.3 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ23619.1 - 0.0022 17.5 0.1 0.0024 17.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ23619.1 - 0.022 14.5 0.1 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 OAJ23619.1 - 0.025 14.0 0.1 0.05 13.0 0.0 1.4 1 1 0 1 1 1 0 PE-PPE domain Abhydrolase_6 PF12697.2 OAJ23619.1 - 0.052 13.4 0.0 0.052 13.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family F-box-like PF12937.2 OAJ23624.1 - 1.4e-09 37.5 0.8 4e-09 36.0 0.6 1.9 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 OAJ23624.1 - 7e-08 32.0 1.2 0.0005 19.8 0.3 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box PF00646.28 OAJ23624.1 - 5.6e-06 25.8 0.9 1.6e-05 24.3 0.6 1.8 1 0 0 1 1 1 1 F-box domain Phage_integrase PF00589.17 OAJ23625.1 - 0.0019 17.9 0.0 0.0022 17.6 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family Zn_clus PF00172.13 OAJ23626.1 - 3.5e-06 26.8 11.3 5.6e-06 26.1 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt5_N PF11942.3 OAJ23626.1 - 0.085 13.4 5.3 3 8.5 0.5 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal F-box PF00646.28 OAJ23627.1 - 1.5e-07 30.9 0.1 3.2e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ23627.1 - 0.015 15.0 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 F-box-like Peroxin-3 PF04882.7 OAJ23629.1 - 8.5e-93 311.4 0.1 3.2e-92 309.5 0.0 1.8 1 1 0 1 1 1 1 Peroxin-3 Acyltransferase PF01553.16 OAJ23630.1 - 3.5e-20 71.7 0.0 7.8e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase DUF1675 PF07897.6 OAJ23630.1 - 0.043 13.6 0.8 0.069 13.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) ELL PF10390.4 OAJ23630.1 - 0.056 12.6 4.1 0.087 12.0 2.8 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL DUF3275 PF11679.3 OAJ23630.1 - 0.087 12.4 3.4 0.19 11.3 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) RVT_1 PF00078.22 OAJ23631.1 - 1.5e-09 37.4 0.0 2.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ATP-synt_E PF05680.7 OAJ23632.1 - 9.4e-23 79.9 0.1 1e-22 79.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain DUF349 PF03993.7 OAJ23632.1 - 0.037 14.1 0.6 0.046 13.8 0.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) KIP1 PF07765.7 OAJ23632.1 - 0.051 13.4 0.7 0.074 12.8 0.5 1.2 1 0 0 1 1 1 0 KIP1-like protein LdpA_C PF12617.3 OAJ23632.1 - 0.072 12.3 0.1 0.082 12.1 0.0 1.1 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal ABC_trans_N PF14510.1 OAJ23632.1 - 0.089 12.8 0.2 0.12 12.4 0.2 1.5 1 1 0 1 1 1 0 ABC-transporter extracellular N-terminal Complex1_30kDa PF00329.14 OAJ23633.1 - 7.7e-35 119.2 0.0 1.1e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Pkinase PF00069.20 OAJ23634.1 - 1.8e-35 122.3 0.0 3.8e-35 121.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ23634.1 - 4.7e-21 75.0 0.0 6.5e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAD_Gly3P_dh_C PF07479.9 OAJ23635.1 - 1.3e-49 167.7 0.1 2.2e-49 167.0 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 OAJ23635.1 - 4.1e-48 163.0 0.0 1.8e-47 160.9 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 OAJ23635.1 - 5.1e-06 26.8 0.7 7.7e-05 23.0 0.5 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 OAJ23635.1 - 0.005 16.2 0.4 0.58 9.5 0.2 2.4 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain DUF3375 PF11855.3 OAJ23635.1 - 0.07 11.8 0.0 0.095 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Pox_VLTF3 PF04947.9 OAJ23635.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like Na_H_Exchanger PF00999.16 OAJ23636.1 - 4.1e-60 203.3 22.5 5.3e-60 202.9 15.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3811 PF11656.3 OAJ23636.1 - 0.045 13.8 0.9 0.13 12.3 0.6 1.7 1 0 0 1 1 1 0 YjbD family (DUF3811) TMCO5 PF14992.1 OAJ23636.1 - 0.048 12.7 1.1 0.076 12.1 0.0 1.8 2 0 0 2 2 2 0 TMCO5 family SCP2 PF02036.12 OAJ23638.1 - 9.7e-10 38.6 0.0 1.9e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 OAJ23638.1 - 0.0064 16.4 0.0 0.0096 15.8 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Pro_isomerase PF00160.16 OAJ23639.1 - 9.8e-42 142.7 0.1 1.3e-41 142.4 0.0 1.2 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glyco_hydro_47 PF01532.15 OAJ23640.1 - 1.3e-114 383.3 0.2 1.6e-114 383.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Bot1p PF12298.3 OAJ23641.1 - 0.061 13.2 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein Perilipin PF03036.11 OAJ23642.1 - 0.00017 20.5 1.2 0.00093 18.1 0.3 2.4 1 1 1 2 2 2 1 Perilipin family MRP-S27 PF10037.4 OAJ23642.1 - 0.038 12.8 0.2 0.057 12.3 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF2408 PF10303.4 OAJ23642.1 - 0.086 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF883 PF05957.8 OAJ23642.1 - 0.086 13.2 0.9 0.7 10.3 0.4 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 OAJ23642.1 - 0.091 12.2 0.7 0.22 11.0 0.5 1.7 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Ring_hydroxyl_A PF00848.14 OAJ23642.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) adh_short PF00106.20 OAJ23646.1 - 0.00074 19.4 0.0 0.58 10.0 0.0 2.8 3 0 0 3 3 3 2 short chain dehydrogenase NOA36 PF06524.7 OAJ23646.1 - 1.4 8.0 3.9 2.3 7.3 2.7 1.2 1 0 0 1 1 1 0 NOA36 protein DHC_N1 PF08385.7 OAJ23647.1 - 3.5e-170 567.2 9.1 3.5e-170 567.2 6.3 3.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 OAJ23647.1 - 1.1e-128 429.2 4.8 1.1e-128 429.2 3.3 3.3 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 OAJ23647.1 - 2.5e-83 279.1 0.0 3.6e-82 275.3 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 OAJ23647.1 - 1.5e-27 96.0 0.0 4.2e-13 49.2 0.0 6.0 6 0 0 6 6 6 3 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 OAJ23647.1 - 1.1e-25 90.1 0.0 2e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 OAJ23647.1 - 1.9e-20 73.1 0.0 1.1e-18 67.3 0.0 3.6 5 0 0 5 5 5 1 P-loop containing dynein motor region D3 AAA PF00004.24 OAJ23647.1 - 6.1e-14 52.3 0.0 0.0057 16.8 0.0 5.4 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ23647.1 - 7.3e-14 52.0 0.1 0.02 14.9 0.0 6.0 6 0 0 6 6 4 3 AAA domain AAA_16 PF13191.1 OAJ23647.1 - 3.2e-10 40.2 0.0 0.011 15.7 0.0 5.5 5 0 0 5 5 5 2 AAA ATPase domain AAA_17 PF13207.1 OAJ23647.1 - 2.3e-09 38.1 0.1 0.21 12.4 0.0 5.8 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.1 OAJ23647.1 - 2.3e-09 37.2 0.0 0.19 11.5 0.0 4.9 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.1 OAJ23647.1 - 8.1e-08 31.9 4.2 0.44 10.3 0.0 5.0 5 0 0 5 5 4 2 Part of AAA domain T2SE PF00437.15 OAJ23647.1 - 3.2e-07 29.5 0.0 0.028 13.3 0.0 3.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_18 PF13238.1 OAJ23647.1 - 8.3e-07 29.3 0.1 0.35 11.1 0.0 4.6 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.12 OAJ23647.1 - 8.9e-06 25.2 0.6 0.34 10.3 0.0 4.3 4 0 0 4 4 4 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 OAJ23647.1 - 2e-05 24.6 0.1 1.5 8.8 0.0 5.4 5 1 0 5 5 4 1 Sigma-54 interaction domain AAA_14 PF13173.1 OAJ23647.1 - 3.1e-05 23.8 0.0 0.53 10.1 0.0 4.4 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.16 OAJ23647.1 - 3.8e-05 22.9 3.0 0.45 9.6 0.0 3.8 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 OAJ23647.1 - 4.3e-05 23.1 0.2 11 5.5 0.0 4.7 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.1 OAJ23647.1 - 0.0017 17.8 0.1 12 5.5 0.0 3.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 OAJ23647.1 - 0.0045 16.4 0.0 4.3 6.7 0.0 3.6 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_25 PF13481.1 OAJ23647.1 - 0.0046 16.3 1.5 1.2 8.4 0.0 3.6 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.17 OAJ23647.1 - 0.014 15.5 0.0 15 5.7 0.0 4.3 4 0 0 4 4 4 0 RNA helicase ABC_tran PF00005.22 OAJ23647.1 - 0.023 15.0 3.9 51 4.1 0.0 5.1 5 0 0 5 5 4 0 ABC transporter AAA_11 PF13086.1 OAJ23647.1 - 0.023 14.2 0.0 2.8 7.4 0.0 3.5 3 0 0 3 3 2 0 AAA domain ResIII PF04851.10 OAJ23647.1 - 0.052 13.3 0.0 3 7.6 0.0 3.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.4 OAJ23647.1 - 0.14 11.6 0.2 49 3.4 0.0 3.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF972 PF06156.8 OAJ23647.1 - 0.28 11.5 1.0 39 4.6 0.0 4.6 4 0 0 4 4 3 0 Protein of unknown function (DUF972) SRP54 PF00448.17 OAJ23647.1 - 0.33 10.3 1.3 49 3.2 0.0 3.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain CRC_subunit PF08624.5 OAJ23648.1 - 4.9e-38 130.1 0.0 8.5e-38 129.3 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit BEX PF04538.7 OAJ23649.1 - 0.014 15.6 0.1 0.016 15.3 0.1 1.2 1 0 0 1 1 1 0 Brain expressed X-linked like family Methyltransf_16 PF10294.4 OAJ23651.1 - 1.9e-08 33.9 0.0 1.2e-07 31.3 0.0 1.9 1 1 0 1 1 1 1 Putative methyltransferase Ribosomal_60s PF00428.14 OAJ23651.1 - 0.76 10.2 4.3 1.8 8.9 2.9 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein RVT_1 PF00078.22 OAJ23654.1 - 4e-22 78.6 0.0 6.7e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ23654.1 - 1.3e-14 53.8 0.1 3.1e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ23654.1 - 1.2e-05 25.3 0.2 2.2e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 OAJ23655.1 - 3.2 7.8 9.9 0.12 12.3 2.1 2.4 2 0 0 2 2 2 0 Zinc knuckle Sad1_UNC PF07738.8 OAJ23656.1 - 1.3e-12 47.6 0.0 6.1e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal RPAP1_N PF08621.5 OAJ23657.1 - 2.6e-06 26.9 1.6 5.7e-06 25.8 1.1 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal RPAP1_C PF08620.5 OAJ23657.1 - 0.0059 16.4 0.8 0.04 13.7 0.0 2.4 2 0 0 2 2 2 1 RPAP1-like, C-terminal Syntaxin PF00804.20 OAJ23657.1 - 0.48 10.6 4.2 1.1 9.4 1.4 2.5 2 0 0 2 2 2 0 Syntaxin Maf1 PF09174.5 OAJ23658.1 - 2.8e-27 95.7 0.0 2e-16 60.3 0.0 3.6 3 0 0 3 3 3 3 Maf1 regulator ETF PF01012.16 OAJ23659.1 - 0.14 11.8 0.0 0.87 9.2 0.0 1.9 2 0 0 2 2 2 0 Electron transfer flavoprotein domain Abhydrolase_5 PF12695.2 OAJ23660.1 - 0.00019 21.2 0.1 0.00078 19.2 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ23660.1 - 0.00022 21.1 0.7 0.0005 20.0 0.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 OAJ23660.1 - 0.00023 20.1 0.0 0.00033 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.15 OAJ23660.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 OAJ23660.1 - 0.042 13.1 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF900 PF05990.7 OAJ23660.1 - 0.13 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.6 OAJ23660.1 - 0.14 11.2 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) zf-rbx1 PF12678.2 OAJ23661.1 - 2.1e-33 114.2 15.5 2.5e-33 114.0 10.7 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 OAJ23661.1 - 1.2e-17 63.5 11.9 1.6e-17 63.1 8.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 OAJ23661.1 - 5.4e-07 29.3 14.4 1.2e-06 28.2 8.5 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAJ23661.1 - 0.00014 21.4 9.5 0.0012 18.4 2.3 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ23661.1 - 0.00027 20.5 10.7 0.003 17.1 7.4 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) VSP PF03302.8 OAJ23661.1 - 0.0062 15.2 2.3 0.0066 15.1 1.6 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein zf-C3HC4_2 PF13923.1 OAJ23661.1 - 0.015 15.2 8.1 0.015 15.2 5.6 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ23661.1 - 0.21 11.3 11.3 1.4 8.7 7.8 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ23661.1 - 0.39 10.4 6.6 11 5.8 4.5 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 OAJ23661.1 - 1.4 8.8 12.7 3.5 7.6 8.8 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 OAJ23661.1 - 2.3 8.4 13.6 36 4.6 9.1 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.3 OAJ23661.1 - 3.3 7.7 16.8 0.22 11.5 6.7 2.3 1 1 2 3 3 3 0 FANCL C-terminal domain Pkinase_Tyr PF07714.12 OAJ23667.1 - 5.5e-09 35.4 0.0 9e-06 24.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 OAJ23667.1 - 1.6e-08 34.0 0.0 3.1e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.18 OAJ23667.1 - 0.00096 18.9 0.1 0.0024 17.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAJ23667.1 - 0.048 13.2 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DDE_Tnp_4 PF13359.1 OAJ23668.1 - 2.2e-22 79.3 0.0 3.4e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 OAJ23668.1 - 0.00059 19.4 5.7 0.00076 19.0 0.2 2.9 2 1 0 2 2 2 1 Transposase DDE domain NAM-associated PF14303.1 OAJ23668.1 - 0.73 10.1 9.6 1.3 9.3 6.6 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain API5 PF05918.6 OAJ23668.1 - 5.3 5.4 6.3 2 6.8 2.7 1.4 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) CR6_interact PF10147.4 OAJ23674.1 - 0.029 13.6 0.4 0.062 12.6 0.3 1.5 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Ribosomal_S14 PF00253.16 OAJ23676.1 - 7e-19 66.9 0.1 1.2e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e QLQ PF08880.6 OAJ23676.1 - 0.15 11.5 1.8 0.19 11.1 0.2 2.0 2 1 0 2 2 2 0 QLQ RNA_pol_Rpb6 PF01192.17 OAJ23677.1 - 3.9e-20 71.3 0.3 5.6e-20 70.8 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Serglycin PF04360.7 OAJ23677.1 - 0.36 10.5 3.9 0.51 10.0 2.7 1.3 1 0 0 1 1 1 0 Serglycin Pkinase PF00069.20 OAJ23678.1 - 1.2e-54 185.2 0.0 2.4e-54 184.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ23678.1 - 1.1e-24 86.9 0.0 1.8e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ23678.1 - 0.0052 16.5 0.2 0.022 14.4 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ23678.1 - 0.021 13.7 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like adh_short_C2 PF13561.1 OAJ23680.1 - 5.7e-28 98.3 0.1 6.7e-28 98.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ23680.1 - 8.2e-27 94.1 1.2 1.1e-26 93.7 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ23680.1 - 7e-11 42.1 0.2 1.1e-10 41.4 0.2 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 OAJ23680.1 - 0.02 14.0 0.0 0.038 13.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 OAJ23680.1 - 0.022 15.1 0.3 0.044 14.2 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 OAJ23680.1 - 0.058 13.1 0.2 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TIM-br_sig_trns PF09370.5 OAJ23680.1 - 0.067 12.2 0.6 0.15 11.1 0.2 1.7 2 0 0 2 2 2 0 TIM-barrel signal transduction protein 3HCDH_N PF02737.13 OAJ23680.1 - 0.15 11.6 0.2 0.24 11.0 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Med7 PF05983.6 OAJ23681.1 - 4.7e-33 114.2 5.1 4.9e-32 110.9 3.5 1.9 1 1 0 1 1 1 1 MED7 protein Rootletin PF15035.1 OAJ23681.1 - 0.0075 16.2 0.5 0.01 15.8 0.3 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DUF607 PF04678.8 OAJ23681.1 - 0.014 15.3 0.2 0.021 14.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF342 PF03961.8 OAJ23681.1 - 0.016 13.6 0.2 0.022 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FAM75 PF14650.1 OAJ23681.1 - 0.083 12.2 2.0 0.11 11.9 0.3 1.7 1 1 1 2 2 2 0 FAM75 family FliJ PF02050.11 OAJ23681.1 - 0.089 12.8 2.3 0.15 12.1 1.6 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein Ribosomal_L12 PF00542.14 OAJ23683.1 - 1.5e-19 69.7 8.7 5.3e-19 67.9 3.8 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Tautomerase_3 PF14832.1 OAJ23685.1 - 2.3e-37 128.0 0.0 2.6e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme PRTase_2 PF15609.1 OAJ23687.1 - 0.056 12.7 0.1 0.085 12.1 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase DUF663 PF04950.7 OAJ23688.1 - 9.1e-78 261.2 0.0 1.2e-76 257.5 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 OAJ23688.1 - 7e-21 73.5 0.0 1.3e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain E1_DerP2_DerF2 PF02221.10 OAJ23691.1 - 1e-25 90.5 0.0 1.2e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 OAJ23691.1 - 0.0049 16.9 0.0 0.0062 16.5 0.0 1.1 1 0 0 1 1 1 1 ML-like domain YTH PF04146.10 OAJ23692.1 - 1.6e-42 144.4 0.0 1e-41 141.7 0.0 2.2 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 OAJ23692.1 - 0.0033 17.0 0.0 0.63 9.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ23692.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glutaredoxin PF00462.19 OAJ23693.1 - 7.7e-19 67.4 0.0 5.1e-18 64.8 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 OAJ23693.1 - 4e-16 58.5 0.0 6.7e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 OAJ23693.1 - 1.4e-05 25.0 0.1 0.017 15.2 0.0 3.0 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ23693.1 - 0.0046 17.1 0.0 0.028 14.5 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.6 OAJ23693.1 - 0.0069 16.2 0.0 0.027 14.3 0.0 1.9 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE GST_N_3 PF13417.1 OAJ23693.1 - 0.02 15.0 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Nucleoplasmin PF03066.10 OAJ23693.1 - 0.027 13.9 0.7 0.034 13.6 0.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin ArsC PF03960.10 OAJ23693.1 - 0.082 12.9 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 ArsC family Sigma70_ner PF04546.8 OAJ23693.1 - 0.084 12.4 1.5 0.13 11.8 1.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 OAJ23693.1 - 0.24 10.5 3.5 0.33 10.0 2.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF726 PF05277.7 OAJ23694.1 - 4.6e-32 111.2 15.4 5.8e-23 81.3 8.1 3.8 2 2 0 2 2 2 2 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 OAJ23694.1 - 8.7e-05 22.5 0.9 0.00022 21.2 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 OAJ23694.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_5 PF12695.2 OAJ23694.1 - 0.0053 16.5 0.1 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 OAJ23694.1 - 0.014 14.6 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 OAJ23694.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF46 PF01864.12 OAJ23694.1 - 6.3 6.6 9.1 13 5.6 3.2 2.4 2 0 0 2 2 2 0 Putative integral membrane protein DUF46 CoA_transf_3 PF02515.12 OAJ23695.1 - 4.8e-67 224.9 0.1 7.9e-67 224.2 0.1 1.3 1 0 0 1 1 1 1 CoA-transferase family III F-box PF00646.28 OAJ23696.1 - 1.5e-07 30.8 1.0 3.7e-07 29.6 0.4 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 OAJ23696.1 - 0.0014 18.2 0.4 0.0052 16.4 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 OAJ23696.1 - 0.0047 16.6 0.1 0.0075 15.9 0.1 1.5 1 1 0 1 1 1 1 F-box-like domain Galactosyl_T PF01762.16 OAJ23699.1 - 1.4e-12 47.6 0.4 2.5e-07 30.5 0.0 3.2 2 1 1 3 3 3 3 Galactosyltransferase Use1 PF09753.4 OAJ23701.1 - 8.7e-05 22.0 0.0 0.00019 20.9 0.0 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 EF-hand_1 PF00036.27 OAJ23702.1 - 5.8e-25 84.6 7.4 3.2e-08 32.3 0.0 4.9 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 OAJ23702.1 - 6.3e-23 80.6 8.7 1.2e-11 44.6 1.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 OAJ23702.1 - 3.3e-21 73.2 1.3 3.3e-06 26.5 0.1 4.6 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 OAJ23702.1 - 9.7e-13 47.5 6.6 0.00035 20.1 0.2 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 OAJ23702.1 - 7.5e-11 40.8 13.7 4.8e-05 22.5 0.0 4.5 5 1 0 5 5 5 3 EF hand EF-hand_4 PF12763.2 OAJ23702.1 - 6.4e-10 38.7 6.0 0.00081 19.0 0.1 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 OAJ23702.1 - 5.7e-06 26.1 0.6 0.00086 19.1 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain Mad3_BUB1_II PF08171.6 OAJ23702.1 - 0.0074 16.1 0.0 0.019 14.8 0.0 1.7 1 1 0 1 1 1 1 Mad3/BUB1 homology region 2 SPARC_Ca_bdg PF10591.4 OAJ23702.1 - 0.033 14.2 1.9 1.5 8.9 0.1 3.0 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.6 OAJ23702.1 - 0.054 13.5 0.0 1.6 8.8 0.0 2.5 2 1 0 2 2 2 0 EF hand S10_plectin PF03501.10 OAJ23702.1 - 0.059 13.2 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Plectin/S10 domain Abhydrolase_6 PF12697.2 OAJ23703.1 - 2.7e-12 47.0 0.5 6.6e-12 45.7 0.4 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ23703.1 - 0.0088 15.6 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DHH PF01368.15 OAJ23704.1 - 0.00015 21.4 0.0 0.00093 18.8 0.0 2.0 1 1 0 1 1 1 1 DHH family zf-H2C2_2 PF13465.1 OAJ23705.1 - 1.1e-09 38.0 17.7 7.8e-06 25.9 2.9 4.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ23705.1 - 2.7e-08 33.6 12.3 0.0007 19.7 1.2 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type HsbA PF12296.3 OAJ23706.1 - 9.7e-12 44.8 4.7 1.5e-11 44.2 3.3 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A CheZ PF04344.8 OAJ23706.1 - 0.013 15.2 0.2 0.016 14.8 0.1 1.3 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Ribosomal_L22 PF00237.14 OAJ23706.1 - 0.1 12.5 2.8 2 8.3 0.2 2.6 2 1 0 2 2 2 0 Ribosomal protein L22p/L17e Helicase_C PF00271.26 OAJ23707.1 - 5.7e-11 42.1 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ23707.1 - 0.019 14.4 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase OrfB_IS605 PF01385.14 OAJ23709.1 - 0.087 12.2 7.5 0.15 11.4 0.4 2.5 1 1 1 2 2 2 0 Probable transposase adh_short PF00106.20 OAJ23714.1 - 0.00047 20.1 0.0 0.00072 19.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Zn_protease PF05618.6 OAJ23715.1 - 0.0079 15.8 0.2 0.0091 15.6 0.1 1.1 1 0 0 1 1 1 1 Putative ATP-dependant zinc protease DUF3375 PF11855.3 OAJ23715.1 - 0.2 10.3 6.0 0.23 10.1 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) DUF3099 PF11298.3 OAJ23715.1 - 4.1 7.2 0.0 4.1 7.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) DUF4171 PF13775.1 OAJ23716.1 - 0.11 12.7 0.1 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) PIF1 PF05970.9 OAJ23717.1 - 9.9e-21 74.0 0.1 3.2e-20 72.3 0.0 1.8 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ23717.1 - 1.1e-10 41.4 0.9 1.3e-09 37.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain Helitron_like_N PF14214.1 OAJ23717.1 - 3.4e-10 39.9 0.1 8.3e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAJ23717.1 - 5.6e-06 26.0 1.0 3.9e-05 23.3 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 OAJ23717.1 - 0.0033 17.4 0.0 0.0097 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ23717.1 - 0.027 14.6 0.0 0.074 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 OAJ23717.1 - 0.12 12.1 0.4 2.9 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Apolipoprotein PF01442.13 OAJ23718.1 - 0.00092 18.7 1.9 0.0011 18.4 1.3 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4164 PF13747.1 OAJ23718.1 - 0.03 14.4 4.5 0.12 12.4 3.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Acyl-CoA_dh_C PF12806.2 OAJ23718.1 - 0.14 11.9 2.1 2.9 7.7 0.0 2.2 1 1 1 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like Mitofilin PF09731.4 OAJ23718.1 - 0.28 9.8 3.5 0.36 9.4 2.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein H_lectin PF09458.5 OAJ23720.1 - 4.9e-05 22.8 0.0 0.001 18.6 0.0 2.8 2 0 0 2 2 2 1 H-type lectin domain RNase_PH_C PF03725.10 OAJ23720.1 - 0.012 15.5 0.1 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Jacalin PF01419.12 OAJ23723.1 - 1.8e-06 27.8 0.0 0.002 18.0 0.0 2.6 2 0 0 2 2 2 2 Jacalin-like lectin domain Histone PF00125.19 OAJ23729.1 - 6.3e-19 67.8 0.1 1e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 MFS_1 PF07690.11 OAJ23730.1 - 2.5e-40 138.2 27.9 1.1e-36 126.3 6.2 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ23730.1 - 2.6e-10 39.4 2.3 2.6e-10 39.4 1.6 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter COX2-transmemb PF09125.5 OAJ23730.1 - 0.32 10.5 0.0 0.32 10.5 0.0 2.4 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane PALP PF00291.20 OAJ23732.1 - 2.7e-75 253.4 0.1 2.7e-75 253.4 0.1 1.7 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 OAJ23732.1 - 2.3e-07 30.2 0.0 0.00016 21.1 0.0 2.9 3 0 0 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase DUF3818 PF12825.2 OAJ23736.1 - 6.1e-36 123.7 0.0 9e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 OAJ23736.1 - 2.7e-22 78.8 0.0 5.4e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 PX-associated NicO PF03824.11 OAJ23737.1 - 6.3e-29 101.1 14.0 3e-12 46.4 0.0 5.0 4 1 1 5 5 5 3 High-affinity nickel-transport protein PDGLE PF13190.1 OAJ23737.1 - 0.03 14.0 3.7 0.045 13.4 0.0 2.9 3 0 0 3 3 3 0 PDGLE domain RNA_pol_Rpb8 PF03870.10 OAJ23738.1 - 2e-37 128.4 0.2 1.1e-35 122.8 0.1 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb8 DUF1900 PF08954.6 OAJ23739.1 - 1.5e-46 157.3 0.0 8.2e-46 154.9 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 OAJ23739.1 - 6.2e-31 105.8 0.3 1.8e-30 104.3 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 OAJ23739.1 - 5.7e-16 57.7 1.5 7.5e-06 25.6 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat PAT1 PF09770.4 OAJ23739.1 - 1.9 6.6 3.5 2.4 6.3 2.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAS PF13851.1 OAJ23740.1 - 1.7 7.7 16.1 3.5 6.7 11.2 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 OAJ23740.1 - 6 6.4 15.8 16 5.0 11.0 1.7 1 0 0 1 1 1 0 IncA protein LCD1 PF09798.4 OAJ23740.1 - 6.5 4.6 10.4 4.3 5.2 0.0 2.2 2 0 0 2 2 2 0 DNA damage checkpoint protein DUF1115 PF06544.7 OAJ23741.1 - 3.5e-06 26.7 0.0 0.00053 19.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1115) DUF2296 PF10058.4 OAJ23743.1 - 2.9e-08 33.3 0.0 6.3e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Med15 PF09606.5 OAJ23743.1 - 0.016 13.4 23.5 0.02 13.1 16.3 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 OAJ23743.1 - 2.7 6.1 24.1 3.3 5.8 16.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 OAJ23743.1 - 5.9 6.1 15.2 7.9 5.7 10.5 1.1 1 0 0 1 1 1 0 Vta1 like polyprenyl_synt PF00348.12 OAJ23744.1 - 2.9e-46 157.4 0.0 1.2e-22 80.0 0.0 3.1 3 0 0 3 3 3 3 Polyprenyl synthetase Sin3_corepress PF08295.7 OAJ23745.1 - 0.024 14.3 1.1 0.036 13.8 0.7 1.4 1 1 0 1 1 1 0 Sin3 family co-repressor Rep_fac-A_C PF08646.5 OAJ23745.1 - 0.091 12.4 1.9 0.1 12.2 1.3 1.1 1 0 0 1 1 1 0 Replication factor-A C terminal domain PHP_C PF13263.1 OAJ23745.1 - 0.16 11.4 0.8 0.53 9.8 0.1 2.0 2 0 0 2 2 2 0 PHP-associated Plasmid_killer PF05015.8 OAJ23745.1 - 0.18 11.9 1.9 0.23 11.6 0.7 1.6 1 1 0 1 1 1 0 Plasmid maintenance system killer protein PmbA_TldD PF01523.11 OAJ23745.1 - 0.37 10.0 2.6 0.48 9.6 1.8 1.2 1 0 0 1 1 1 0 Putative modulator of DNA gyrase DUF2587 PF10759.4 OAJ23745.1 - 0.77 9.1 7.0 1 8.7 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2587) Pol_alpha_B_N PF08418.5 OAJ23745.1 - 5.1 6.5 7.0 69 2.8 4.8 2.0 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal CwfJ_C_1 PF04677.10 OAJ23747.1 - 1.3e-21 76.4 0.0 3.1e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 OAJ23747.1 - 3.3e-13 49.9 0.1 8.2e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_2 PF13696.1 OAJ23747.1 - 1.7e-09 36.9 6.4 8.7e-06 25.1 1.2 2.6 2 0 0 2 2 2 2 Zinc knuckle Oxidored_FMN PF00724.15 OAJ23749.1 - 8.8e-50 169.6 0.0 2e-39 135.5 0.0 3.1 3 0 0 3 3 3 3 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 OAJ23749.1 - 0.014 14.6 0.0 4.8 6.4 0.0 2.4 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel MutL PF13941.1 OAJ23749.1 - 0.043 12.1 0.1 0.065 11.5 0.1 1.2 1 0 0 1 1 1 0 MutL protein Dus PF01207.12 OAJ23749.1 - 0.24 10.2 0.1 0.56 8.9 0.0 1.6 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) SNARE_assoc PF09335.6 OAJ23750.1 - 1.5e-21 76.9 7.7 2.9e-14 53.3 0.0 3.1 4 0 0 4 4 4 2 SNARE associated Golgi protein Myb_DNA-binding PF00249.26 OAJ23751.1 - 1.6e-10 40.8 0.0 1.9e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain MIP-T3 PF10243.4 OAJ23751.1 - 1.3e-05 23.9 12.2 1.3e-05 23.9 8.5 5.5 4 1 0 4 4 4 1 Microtubule-binding protein MIP-T3 UQ_con PF00179.21 OAJ23752.1 - 8.7e-53 177.5 0.0 9.8e-53 177.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ23752.1 - 0.00012 21.8 0.0 0.00014 21.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 OAJ23752.1 - 0.013 15.4 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 OAJ23752.1 - 0.044 13.4 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain MSA-2c PF12238.3 OAJ23753.1 - 0.01 15.4 3.3 0.01 15.4 2.3 2.0 1 1 1 2 2 2 0 Merozoite surface antigen 2c Na_Ca_ex PF01699.19 OAJ23761.1 - 5e-24 84.4 9.3 5e-24 84.4 6.4 1.6 2 0 0 2 2 2 1 Sodium/calcium exchanger protein Ribosomal_60s PF00428.14 OAJ23762.1 - 4.1 7.8 19.0 2.2 8.7 6.4 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein Npa1 PF11707.3 OAJ23763.1 - 5e-66 222.9 0.0 1.1e-41 142.9 0.0 3.6 4 1 0 4 4 4 2 Ribosome 60S biogenesis N-terminal HEAT PF02985.17 OAJ23763.1 - 0.15 12.2 2.8 8.9 6.6 0.1 4.7 4 0 0 4 4 4 0 HEAT repeat Lactonase PF10282.4 OAJ23765.1 - 1.3e-67 228.3 0.0 1.6e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Na_Ca_ex PF01699.19 OAJ23767.1 - 3.4e-22 78.5 12.5 6.4e-22 77.6 8.7 1.5 1 0 0 1 1 1 1 Sodium/calcium exchanger protein CDC45 PF02724.9 OAJ23767.1 - 0.83 7.6 12.6 0.24 9.3 1.9 2.1 2 0 0 2 2 2 0 CDC45-like protein Nucleoplasmin PF03066.10 OAJ23767.1 - 2 7.9 8.6 0.24 10.8 1.7 2.4 2 0 0 2 2 2 0 Nucleoplasmin MSP1_C PF07462.6 OAJ23767.1 - 4 5.7 4.2 5.8 5.1 2.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus AbiH PF14253.1 OAJ23768.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH RRM_1 PF00076.17 OAJ23770.1 - 3.7e-12 45.7 0.0 5e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ23770.1 - 2.5e-08 33.7 0.0 3.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ23770.1 - 0.00014 21.6 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAJ23770.1 - 0.00024 20.7 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif SET PF00856.23 OAJ23771.1 - 2.6e-23 83.0 3.3 1.7e-22 80.4 0.2 2.8 2 1 0 2 2 2 1 SET domain SRI PF08236.6 OAJ23771.1 - 2e-15 56.5 3.5 2e-15 56.5 2.4 2.2 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 OAJ23771.1 - 0.0049 16.3 0.1 0.02 14.3 0.0 2.1 1 0 0 1 1 1 1 TFIIS helical bundle-like domain GNAT_acetyltr_2 PF13718.1 OAJ23772.1 - 2.8e-64 216.0 0.0 4.4e-64 215.4 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 OAJ23772.1 - 1.4e-51 174.6 0.0 2.4e-51 173.8 0.0 1.4 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 OAJ23772.1 - 7.8e-32 108.8 0.0 1.7e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 OAJ23772.1 - 1.8e-24 85.7 0.1 5.5e-24 84.2 0.1 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain NIF PF03031.13 OAJ23773.1 - 1.1e-07 31.7 0.0 0.0062 16.2 0.0 3.5 4 0 0 4 4 4 2 NLI interacting factor-like phosphatase Endonuclease_NS PF01223.18 OAJ23774.1 - 4.1e-51 173.5 0.0 5.9e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease RabGAP-TBC PF00566.13 OAJ23775.1 - 4e-50 170.2 0.0 5.4e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_1 PF00018.23 OAJ23775.1 - 0.0072 15.6 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ23775.1 - 0.0086 15.5 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Autophagy_act_C PF03987.10 OAJ23776.1 - 7.7e-11 42.0 4.0 6.2e-10 39.1 2.8 2.3 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Asp PF00026.18 OAJ23782.1 - 2.4e-48 165.0 7.0 7.5e-48 163.3 4.9 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 OAJ23782.1 - 0.00056 19.5 0.0 0.0018 17.8 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 OAJ23782.1 - 0.0024 17.8 4.4 0.017 15.0 2.5 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAJ23782.1 - 0.004 17.6 2.9 0.03 14.8 0.7 2.5 2 0 0 2 2 2 1 Aspartyl protease Rpr2 PF04032.11 OAJ23784.1 - 3.6e-13 49.2 0.0 5.9e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.2 OAJ23784.1 - 0.002 17.8 1.4 0.0038 16.9 0.9 1.4 1 0 0 1 1 1 1 Double zinc ribbon GFA PF04828.9 OAJ23784.1 - 0.019 14.8 0.5 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.11 OAJ23784.1 - 0.16 11.6 0.5 0.75 9.5 0.0 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit SMC_N PF02463.14 OAJ23785.1 - 1.9e-27 95.9 0.0 6e-27 94.3 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAJ23785.1 - 7.9e-08 32.8 33.4 7.9e-08 32.8 23.2 5.4 3 2 0 3 3 3 1 AAA domain AAA_21 PF13304.1 OAJ23785.1 - 6.7e-06 26.2 0.5 0.13 12.1 0.2 3.0 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 OAJ23785.1 - 2.2e-05 23.6 2.0 2.2e-05 23.6 1.4 2.1 2 1 0 2 2 2 1 AAA ATPase domain Reo_sigmaC PF04582.7 OAJ23785.1 - 0.00019 20.7 8.8 0.69 9.0 0.7 4.4 3 1 1 4 4 4 3 Reovirus sigma C capsid protein SbcCD_C PF13558.1 OAJ23785.1 - 0.0009 19.1 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 OAJ23785.1 - 0.0015 18.0 0.3 0.0042 16.5 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 OAJ23785.1 - 0.0066 14.9 69.3 0.027 12.9 8.5 5.6 3 3 3 6 6 6 4 AAA domain Fer4_NifH PF00142.13 OAJ23785.1 - 1.5 7.9 6.2 0.33 10.0 0.5 2.4 2 1 1 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RNase_HII PF01351.13 OAJ23786.1 - 1.4e-41 142.3 0.0 1.1e-37 129.6 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease HII Hepar_II_III PF07940.8 OAJ23787.1 - 0.038 13.8 0.1 2.1 8.1 0.1 2.5 2 0 0 2 2 2 0 Heparinase II/III-like protein API5 PF05918.6 OAJ23787.1 - 0.67 8.3 4.4 1.2 7.6 3.0 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Mannosyl_trans PF05007.8 OAJ23790.1 - 1.2e-52 179.1 19.0 3.7e-48 164.4 11.1 3.5 2 1 0 2 2 2 2 Mannosyltransferase (PIG-M) Piwi PF02171.12 OAJ23791.1 - 2e-73 247.0 0.0 2.9e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 OAJ23791.1 - 3e-18 65.4 0.0 8.3e-18 63.9 0.0 1.7 2 0 0 2 2 2 1 PAZ domain DUF1785 PF08699.5 OAJ23791.1 - 1.7e-09 36.9 0.2 4.9e-09 35.4 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Alpha-amyl_C2 PF07821.7 OAJ23791.1 - 0.038 13.8 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Alpha-amylase C-terminal beta-sheet domain DUF1797 PF08796.5 OAJ23791.1 - 0.041 13.7 0.5 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) DNA_pol_A_exo1 PF01612.15 OAJ23792.1 - 3e-38 131.0 0.2 4.4e-38 130.4 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 OAJ23792.1 - 4.9e-15 55.6 0.0 1.1e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 OAJ23792.1 - 8.8e-12 44.5 0.2 1.8e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 HRDC domain WD40 PF00400.27 OAJ23793.1 - 3.9e-26 89.9 17.3 5.3e-06 26.0 0.0 6.7 6 1 0 6 6 6 5 WD domain, G-beta repeat CLTH PF10607.4 OAJ23793.1 - 8.6e-06 25.5 0.1 1.4e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SGL PF08450.7 OAJ23793.1 - 0.0018 17.7 0.0 0.095 12.0 0.0 2.7 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region HLH PF00010.21 OAJ23794.1 - 5.4e-05 22.7 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain E1_dh PF00676.15 OAJ23796.1 - 1e-56 191.8 1.3 1.3e-56 191.5 0.9 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 OAJ23796.1 - 0.00035 19.5 0.0 0.00072 18.5 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 OAJ23796.1 - 0.011 15.2 1.1 0.027 14.0 0.6 1.7 1 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Herpes_UL32 PF06070.6 OAJ23796.1 - 0.1 11.0 0.5 0.099 11.0 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 V-ATPase_H_N PF03224.9 OAJ23797.1 - 4.3e-79 265.8 0.0 1.4e-78 264.2 0.0 1.8 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 OAJ23797.1 - 5.3e-31 106.9 0.0 2.3e-30 104.9 0.0 2.2 1 1 0 1 1 1 1 V-ATPase subunit H HEAT PF02985.17 OAJ23797.1 - 0.0015 18.4 0.0 0.12 12.5 0.0 2.8 2 0 0 2 2 2 1 HEAT repeat ORC6 PF05460.8 OAJ23797.1 - 0.11 11.5 2.2 0.22 10.6 1.5 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ORC2 PF04084.9 OAJ23802.1 - 2.8e-37 128.3 0.0 2e-31 109.0 0.0 2.1 2 0 0 2 2 2 2 Origin recognition complex subunit 2 OATP PF03137.15 OAJ23802.1 - 0.034 12.2 0.0 0.11 10.5 0.0 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TFIID_30kDa PF03540.8 OAJ23802.1 - 0.079 12.7 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit PBP1_TM PF14812.1 OAJ23802.1 - 5.8 7.2 21.3 1.7 8.9 0.0 5.3 6 0 0 6 6 6 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPP_enzyme_N PF02776.13 OAJ23803.1 - 1.7e-54 183.8 0.0 1.7e-54 183.8 0.0 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 OAJ23803.1 - 9.3e-48 161.6 0.1 3.2e-46 156.6 0.0 2.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAJ23803.1 - 6.2e-38 129.6 0.7 1.5e-37 128.4 0.2 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain RhoGAP PF00620.22 OAJ23804.1 - 1.4e-06 27.9 0.1 7.2e-05 22.4 0.0 3.3 3 1 0 3 3 3 1 RhoGAP domain FCH PF00611.18 OAJ23804.1 - 0.00021 21.3 0.1 0.0069 16.5 0.0 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain NIF PF03031.13 OAJ23805.1 - 1.2e-49 168.0 0.1 1.9e-49 167.4 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Nucleoplasmin PF03066.10 OAJ23805.1 - 0.82 9.1 9.6 1.5 8.2 6.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 OAJ23805.1 - 4 7.0 12.8 10 5.6 8.9 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 OAJ23805.1 - 8.3 5.5 7.8 14 4.8 5.4 1.2 1 0 0 1 1 1 0 NOA36 protein Aldose_epim PF01263.15 OAJ23806.1 - 3e-57 194.0 0.1 4.9e-57 193.3 0.1 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase SQS_PSY PF00494.14 OAJ23807.1 - 1e-46 159.3 1.3 1.3e-46 159.0 0.9 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase BCIP PF13862.1 OAJ23808.1 - 3e-32 111.7 0.0 5e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Spt5_N PF11942.3 OAJ23808.1 - 0.0053 17.3 13.0 0.091 13.3 1.0 2.5 2 0 0 2 2 2 2 Spt5 transcription elongation factor, acidic N-terminal Sigma70_ner PF04546.8 OAJ23808.1 - 0.054 13.1 6.8 0.45 10.1 0.2 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Myc_N PF01056.13 OAJ23808.1 - 0.057 12.5 2.6 3.6 6.6 0.7 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Nucleoplasmin PF03066.10 OAJ23808.1 - 0.062 12.8 5.9 0.97 8.9 0.6 2.5 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 OAJ23808.1 - 0.065 13.5 13.3 0.11 12.7 0.7 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TLP-20 PF06088.6 OAJ23808.1 - 0.63 9.6 3.7 5 6.7 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF4611 PF15387.1 OAJ23808.1 - 0.89 9.7 8.8 1.3 9.1 2.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FAM176 PF14851.1 OAJ23808.1 - 1.7 8.3 4.8 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 FAM176 family UPF0560 PF10577.4 OAJ23808.1 - 9.1 4.3 7.4 1.1 7.4 1.5 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 MFS_1 PF07690.11 OAJ23809.1 - 2.9e-46 157.7 38.2 2.2e-45 154.8 11.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ23809.1 - 3.4e-08 32.4 10.7 3.4e-08 32.4 7.4 3.5 2 2 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 OAJ23809.1 - 2.2e-06 26.0 1.4 0.00022 19.4 1.0 2.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.8 OAJ23809.1 - 1.2e-05 23.7 4.4 2.3e-05 22.7 3.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 OAJ23809.1 - 0.0014 16.8 4.3 0.0029 15.7 3.0 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector DUF4231 PF14015.1 OAJ23809.1 - 0.018 15.0 7.3 3.1 7.8 0.5 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF21 PF01595.15 OAJ23809.1 - 0.025 13.8 0.9 0.025 13.8 0.6 3.0 2 0 0 2 2 2 0 Domain of unknown function DUF21 ESSS PF10183.4 OAJ23809.1 - 0.063 13.6 0.2 0.26 11.6 0.1 2.0 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) JmjC PF02373.17 OAJ23810.1 - 1.3e-40 138.1 0.1 3e-40 136.9 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 OAJ23810.1 - 9.7e-12 44.2 0.1 2.2e-11 43.0 0.1 1.7 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 OAJ23810.1 - 1.2e-09 38.1 1.7 1.2e-09 38.1 1.2 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 OAJ23810.1 - 2.3e-09 37.2 4.0 1.4e-08 34.6 1.1 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-C3HC4_3 PF13920.1 OAJ23811.1 - 3.8e-06 26.4 7.7 3.8e-06 26.4 5.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 OAJ23811.1 - 9.4 6.8 24.1 0.14 12.5 0.4 5.6 6 0 0 6 6 6 0 Zinc finger, C2H2 type Abhydrolase_6 PF12697.2 OAJ23812.1 - 2.1e-30 106.3 3.9 2.2e-30 106.2 0.2 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ23812.1 - 3.9e-18 65.8 0.0 2.3e-17 63.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ23812.1 - 7.7e-13 48.4 0.0 5e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 OAJ23812.1 - 5.3e-06 26.1 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_3 PF07859.8 OAJ23812.1 - 0.00033 20.3 0.4 0.0027 17.3 0.0 2.4 1 1 2 3 3 3 1 alpha/beta hydrolase fold Esterase PF00756.15 OAJ23812.1 - 0.0011 18.4 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.6 OAJ23812.1 - 0.0024 17.6 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 OAJ23812.1 - 0.0084 15.5 0.0 5.4 6.3 0.0 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Ndr PF03096.9 OAJ23812.1 - 0.029 12.8 0.0 0.05 12.0 0.0 1.3 1 0 0 1 1 1 0 Ndr family Hydrolase_4 PF12146.3 OAJ23812.1 - 0.085 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase DUF2305 PF10230.4 OAJ23812.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) PBP1_TM PF14812.1 OAJ23814.1 - 0.21 11.9 9.7 0.23 11.7 1.7 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 OAJ23814.1 - 4.4 7.0 7.6 1.3 8.8 0.8 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal TRAM_LAG1_CLN8 PF03798.11 OAJ23815.1 - 3.8e-32 111.4 11.8 5.9e-32 110.8 8.2 1.3 1 0 0 1 1 1 1 TLC domain zf-HIT PF04438.11 OAJ23816.1 - 7.8e-08 31.8 9.6 1.4e-07 31.0 6.6 1.3 1 0 0 1 1 1 1 HIT zinc finger NUDIX PF00293.23 OAJ23821.1 - 1.7e-12 47.0 0.0 1.3e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain Golgin_A5 PF09787.4 OAJ23821.1 - 0.11 11.0 0.8 0.16 10.4 0.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1768 PF08719.6 OAJ23822.1 - 0.00012 21.8 0.0 0.00015 21.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1768 PF08719.6 OAJ23823.1 - 5.7e-24 84.6 0.0 2.1e-23 82.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1768) DUF1768 PF08719.6 OAJ23824.1 - 7.1e-23 81.0 0.2 1.2e-22 80.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1768 PF08719.6 OAJ23826.1 - 2.4e-19 69.5 1.6 1.4e-12 47.6 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF1768) GCS PF03074.11 OAJ23827.1 - 5.9e-149 496.1 0.0 1.4e-123 412.6 0.0 2.8 3 0 0 3 3 3 2 Glutamate-cysteine ligase TFIIA PF03153.8 OAJ23827.1 - 0.78 9.5 3.9 1.6 8.5 2.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PBP1_TM PF14812.1 OAJ23827.1 - 3.5 7.9 7.2 13 6.2 5.0 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RIO1 PF01163.17 OAJ23828.1 - 1.7e-38 131.8 0.1 1.6e-26 92.8 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 OAJ23828.1 - 3.8e-29 100.5 0.0 8e-29 99.5 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 OAJ23828.1 - 2.9e-07 30.4 1.1 0.00039 20.2 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 OAJ23828.1 - 0.0077 15.3 0.0 0.049 12.6 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MarR_2 PF12802.2 OAJ23828.1 - 0.055 13.1 0.2 0.63 9.7 0.1 2.3 2 0 0 2 2 2 0 MarR family DUF4423 PF14394.1 OAJ23829.1 - 0.038 13.5 0.2 25 4.3 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4423) MotA_activ PF09114.5 OAJ23829.1 - 0.046 13.4 13.4 6.2 6.6 0.1 5.6 4 1 3 7 7 7 0 Transcription factor MotA, activation domain AcylCoA_dehyd_C PF12186.3 OAJ23829.1 - 0.058 13.2 5.5 44 3.9 0.0 6.0 7 1 0 7 7 7 0 Acyl-CoA dehydrogenase C terminal DUF2540 PF10802.3 OAJ23829.1 - 0.061 13.0 1.8 3.2 7.4 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2540) DrsE_2 PF13686.1 OAJ23829.1 - 0.084 12.6 0.8 19 4.9 0.0 3.9 5 0 0 5 5 5 0 DsrE/DsrF/DrsH-like family DAG_kinase_N PF14513.1 OAJ23829.1 - 4 7.6 10.2 11 6.2 0.1 5.3 3 2 3 7 7 7 0 Diacylglycerol kinase N-terminus Strep_pep PF14404.1 OAJ23829.1 - 5.2 7.3 21.7 11 6.3 0.1 7.1 4 3 3 8 8 8 0 Ribosomally synthesized peptide in Streptomyces species Lon_C PF05362.8 OAJ23830.1 - 2.1e-66 223.1 0.2 4.7e-66 222.0 0.1 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 OAJ23830.1 - 1.3e-31 109.8 0.0 2.7e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 OAJ23830.1 - 1.6e-21 76.8 0.0 5.7e-21 75.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 OAJ23830.1 - 5.9e-07 29.0 0.0 1.8e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 OAJ23830.1 - 3.1e-06 27.2 0.0 5.6e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 OAJ23830.1 - 6.7e-06 25.8 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 OAJ23830.1 - 4.6e-05 23.4 0.2 0.00048 20.1 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.6 OAJ23830.1 - 6.1e-05 21.8 0.0 0.0001 21.1 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 OAJ23830.1 - 0.001 19.8 0.3 0.0036 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAJ23830.1 - 0.0012 18.9 0.1 0.038 14.1 0.0 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAJ23830.1 - 0.0017 17.4 0.0 0.0085 15.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 OAJ23830.1 - 0.0024 17.7 0.0 0.0057 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ23830.1 - 0.0071 16.6 1.4 0.012 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 OAJ23830.1 - 0.021 14.2 0.0 0.058 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 OAJ23830.1 - 0.024 14.3 1.9 8.6 5.9 0.0 3.4 2 1 0 3 3 3 0 Archaeal ATPase TIP49 PF06068.8 OAJ23830.1 - 0.03 13.0 3.1 0.91 8.1 0.0 2.6 3 0 0 3 3 3 0 TIP49 C-terminus RNA_helicase PF00910.17 OAJ23830.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 OAJ23830.1 - 0.053 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 OAJ23830.1 - 0.06 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 GUCT PF08152.7 OAJ23830.1 - 0.089 12.7 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 GUCT (NUC152) domain Y_phosphatase2 PF03162.8 OAJ23832.1 - 2.4e-22 79.0 0.0 3.1e-13 49.4 0.0 2.5 3 0 0 3 3 3 2 Tyrosine phosphatase family Ribosomal_60s PF00428.14 OAJ23832.1 - 1.7e-05 25.1 1.5 3.3e-05 24.2 1.0 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein NOA36 PF06524.7 OAJ23832.1 - 0.63 9.2 6.4 1.1 8.4 4.4 1.3 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 OAJ23832.1 - 2 7.9 16.6 4.6 6.7 11.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 OAJ23832.1 - 2.9 7.4 14.8 0.52 9.9 6.8 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region BSP_II PF05432.6 OAJ23832.1 - 5.7 6.1 18.9 3.5 6.8 10.4 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Sporozoite_P67 PF05642.6 OAJ23832.1 - 6.5 4.4 7.8 0.49 8.1 1.0 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF2722 PF10846.3 OAJ23832.1 - 6.8 5.6 8.5 10 5.0 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RXT2_N PF08595.6 OAJ23832.1 - 9.1 6.0 10.1 9.3 6.0 5.8 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal muHD PF10291.4 OAJ23833.1 - 5.6e-38 130.6 0.0 8.6e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 OAJ23833.1 - 3.3e-07 30.3 0.2 1.1e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Adap_comp_sub PF00928.16 OAJ23833.1 - 1.3e-05 24.4 0.0 7.9e-05 21.8 0.0 1.9 1 1 0 1 1 1 1 Adaptor complexes medium subunit family HrpB7 PF09486.5 OAJ23833.1 - 0.0033 17.3 3.1 0.0077 16.1 2.1 1.5 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) DDE_3 PF13358.1 OAJ23834.1 - 2.3e-29 102.0 0.0 3.2e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 OAJ23834.1 - 0.00012 21.2 0.0 0.00014 21.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 OAJ23834.1 - 0.0024 17.9 0.0 0.0041 17.2 0.0 1.4 2 0 0 2 2 2 1 Integrase core domain PPDK_N PF01326.14 OAJ23834.1 - 0.18 10.8 0.5 0.24 10.4 0.4 1.1 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Ank_2 PF12796.2 OAJ23835.1 - 3.1e-21 75.5 0.1 2.9e-09 37.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ23835.1 - 6.9e-21 74.2 0.8 4.5e-12 46.1 0.1 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ23835.1 - 1.5e-17 63.1 0.5 2.7e-08 33.7 0.0 3.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 OAJ23835.1 - 1.6e-17 62.3 0.0 3.9e-07 29.5 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 OAJ23835.1 - 1.1e-15 56.1 0.5 0.00019 21.3 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat KilA-N PF04383.8 OAJ23835.1 - 9.9e-06 25.1 1.3 5.1e-05 22.8 0.1 2.4 2 1 0 2 2 2 1 KilA-N domain BTB PF00651.26 OAJ23835.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain DUF4407 PF14362.1 OAJ23835.1 - 1.2 7.9 11.4 0.12 11.2 4.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Epimerase PF01370.16 OAJ23836.1 - 1.5e-19 70.3 0.0 2.3e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAJ23836.1 - 1.1e-14 53.7 0.0 6.8e-14 51.2 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 OAJ23836.1 - 1.5e-09 37.1 0.0 2.7e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein TcpF PF06340.6 OAJ23836.1 - 0.0005 19.2 0.1 0.00081 18.6 0.1 1.3 1 0 0 1 1 1 1 Vibrio cholerae toxin co-regulated pilus biosynthesis protein F RmlD_sub_bind PF04321.12 OAJ23836.1 - 0.016 14.0 0.0 0.042 12.7 0.0 1.7 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 OAJ23836.1 - 0.15 11.2 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family zf-C3HC4_3 PF13920.1 OAJ23838.1 - 4.1e-10 39.1 4.2 6.4e-10 38.5 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ23838.1 - 1.1e-05 25.3 5.1 2.2e-05 24.3 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ23838.1 - 1.6e-05 24.4 4.2 2.8e-05 23.6 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ23838.1 - 2.5e-05 24.0 5.1 4.8e-05 23.1 3.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAJ23838.1 - 0.00071 19.2 4.0 0.0013 18.3 2.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 OAJ23838.1 - 1.5 8.4 4.1 4.2 7.0 2.8 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain CRAL_TRIO PF00650.15 OAJ23839.1 - 2.7e-27 95.2 0.0 4.9e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ23839.1 - 6.5e-10 38.9 0.4 2.1e-09 37.3 0.3 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Brr6_like_C_C PF10104.4 OAJ23840.1 - 2.6e-34 117.6 0.1 3.4e-34 117.2 0.1 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain p450 PF00067.17 OAJ23841.1 - 6.7e-60 202.9 0.6 1.3e-49 169.0 0.4 3.8 1 1 1 2 2 2 2 Cytochrome P450 TM_helix PF05552.7 OAJ23841.1 - 2 8.1 6.4 4.1 7.1 4.4 1.5 1 0 0 1 1 1 0 Conserved TM helix Pet127 PF08634.5 OAJ23845.1 - 4.3e-104 347.5 0.1 5.7e-104 347.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 zf-DHHC PF01529.15 OAJ23846.1 - 1e-33 116.1 7.7 1.6e-33 115.5 5.3 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_2 PF12796.2 OAJ23846.1 - 4.2e-33 113.5 3.1 3.6e-11 43.2 0.0 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ23846.1 - 1.7e-28 96.9 11.6 1.6e-07 30.7 0.1 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 OAJ23846.1 - 1.3e-26 92.4 4.9 1.3e-10 41.5 0.1 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ23846.1 - 2.3e-21 75.3 7.5 4.2e-06 26.8 0.1 6.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ23846.1 - 2e-18 64.6 3.3 0.00045 20.1 0.0 6.2 5 0 0 5 5 5 4 Ankyrin repeat DUF1843 PF08898.5 OAJ23846.1 - 3.7 7.6 10.4 6.6 6.8 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) PrgI PF12666.2 OAJ23846.1 - 6 7.0 5.8 2.2 8.4 0.8 2.4 2 0 0 2 2 2 0 PrgI family protein DEAD PF00270.24 OAJ23849.1 - 4.3e-16 58.8 0.0 2.2e-15 56.5 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ23849.1 - 0.032 14.0 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain PhoH PF02562.11 OAJ23849.1 - 0.24 10.6 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein NAD_binding_10 PF13460.1 OAJ23851.1 - 3.8e-09 36.8 0.0 1.4e-08 34.9 0.0 2.0 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAJ23851.1 - 8.7e-05 22.0 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAJ23851.1 - 0.024 13.3 0.0 0.037 12.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 OAJ23851.1 - 0.033 13.0 0.0 0.33 9.8 0.0 2.5 2 1 1 3 3 3 0 RmlD substrate binding domain adh_short PF00106.20 OAJ23851.1 - 0.071 13.0 0.1 0.21 11.4 0.0 1.8 1 1 0 1 1 1 0 short chain dehydrogenase RVT_2 PF07727.9 OAJ23852.1 - 2.4e-83 278.9 0.0 3.4e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ23852.1 - 5.7e-21 74.8 0.2 3.3e-20 72.3 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ23852.1 - 5.8e-06 25.8 0.0 2.1e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ23852.1 - 1.1e-05 24.8 0.0 3.3e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain UBN2 PF14223.1 OAJ23852.1 - 0.002 17.8 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RVT_1 PF00078.22 OAJ23852.1 - 0.099 11.9 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Tcp11 PF05794.8 OAJ23853.1 - 9.2e-07 27.9 0.0 0.44 9.2 0.0 3.2 3 0 0 3 3 3 3 T-complex protein 11 ABC_tran PF00005.22 OAJ23854.1 - 3.2e-41 140.8 0.0 2.7e-26 92.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 OAJ23854.1 - 1.7e-40 139.1 29.8 4.3e-25 88.6 9.2 3.5 4 0 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.14 OAJ23854.1 - 1.7e-08 33.9 2.9 0.011 15.0 0.0 4.5 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAJ23854.1 - 2.6e-05 24.6 0.0 0.19 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAJ23854.1 - 0.00011 21.6 0.2 0.14 11.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 OAJ23854.1 - 0.0026 17.2 1.2 0.57 9.5 0.3 3.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAJ23854.1 - 0.0088 16.1 1.6 3.8 7.6 0.0 3.6 4 0 0 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.13 OAJ23854.1 - 0.0088 15.5 0.1 2.5 7.5 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 OAJ23854.1 - 0.0098 15.7 0.2 0.0098 15.7 0.2 1.8 2 0 0 2 2 1 1 Domain of unknown function DUF87 AAA_10 PF12846.2 OAJ23854.1 - 0.015 14.7 0.6 3.3 7.0 0.1 2.8 2 1 0 3 3 3 0 AAA-like domain AAA_16 PF13191.1 OAJ23854.1 - 0.034 14.1 1.5 0.23 11.4 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 OAJ23854.1 - 0.044 13.9 0.4 4.6 7.4 0.1 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 OAJ23854.1 - 0.059 13.2 0.3 13 5.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 OAJ23854.1 - 0.067 13.6 1.3 3.4 8.1 0.2 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 OAJ23854.1 - 0.15 12.9 0.3 0.58 10.9 0.0 2.2 2 0 0 2 2 1 0 AAA domain ATP-synt_ab PF00006.20 OAJ23854.1 - 0.16 11.4 0.7 0.46 9.9 0.1 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 OAJ23854.1 - 0.17 11.0 0.3 15 4.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 OAJ23854.1 - 0.17 12.0 1.0 2.9 8.1 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_18 PF13238.1 OAJ23854.1 - 0.18 12.0 0.1 3.3 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 OAJ23854.1 - 0.19 11.6 2.8 2.4 8.0 0.0 2.9 3 1 0 3 3 3 0 AAA domain UBN2 PF14223.1 OAJ23855.1 - 3.1e-05 23.7 0.0 5.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ23855.1 - 0.33 10.9 2.2 0.59 10.1 1.5 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.9 OAJ23856.1 - 5.2e-90 300.7 0.0 7.2e-90 300.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ23856.1 - 7.9e-20 71.1 0.0 7.1e-19 68.0 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ23856.1 - 1.3e-05 24.7 0.0 5.3e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain RVT_2 PF07727.9 OAJ23858.1 - 2.1e-34 118.5 0.0 2.7e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Voldacs PF03517.8 OAJ23858.1 - 2.5e-19 69.4 0.0 4.2e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling GRAM PF02893.15 OAJ23858.1 - 0.037 13.5 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 GRAM domain NOA36 PF06524.7 OAJ23858.1 - 0.22 10.7 1.3 0.34 10.1 0.9 1.2 1 0 0 1 1 1 0 NOA36 protein zf-DHHC PF01529.15 OAJ23859.1 - 4.6e-41 140.1 3.0 4.6e-41 140.1 2.1 2.4 3 1 1 4 4 4 1 DHHC palmitoyltransferase Spt4 PF06093.8 OAJ23859.1 - 0.38 10.6 3.1 0.94 9.4 2.2 1.7 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Skp1_POZ PF03931.10 OAJ23860.1 - 0.00042 20.3 0.0 0.00083 19.4 0.0 1.5 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain RVT_1 PF00078.22 OAJ23861.1 - 3.2e-19 69.1 0.0 5.9e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ23861.1 - 4.1e-14 52.7 0.0 1.4e-13 50.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ23861.1 - 9.1e-05 22.8 0.0 0.00029 21.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ23861.1 - 0.022 14.6 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ23861.1 - 0.025 14.3 0.1 0.07 12.9 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Sod_Fe_C PF02777.13 OAJ23862.1 - 1.4e-36 124.5 0.1 2.7e-36 123.6 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 OAJ23862.1 - 1.6e-32 111.6 3.2 3.1e-32 110.6 2.2 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ATP-synt_DE PF00401.15 OAJ23862.1 - 3 7.7 7.4 0.47 10.3 0.4 2.8 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain RRM_1 PF00076.17 OAJ23863.1 - 3.6e-58 193.0 0.0 1.2e-19 69.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ23863.1 - 1.2e-44 150.1 0.0 7.2e-14 51.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ23863.1 - 5.6e-32 109.3 0.0 1.2e-10 41.0 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAJ23863.1 - 0.0022 17.7 0.0 7.9 6.3 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 OAJ23863.1 - 0.15 12.0 0.0 26 4.8 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) GST_N_3 PF13417.1 OAJ23869.1 - 0.00022 21.3 0.0 0.0016 18.5 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain DUF1365 PF07103.6 OAJ23870.1 - 1.4e-21 76.6 0.0 4.6e-20 71.7 0.0 3.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) HLH PF00010.21 OAJ23871.1 - 1.9e-16 59.5 0.2 4.9e-16 58.1 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_60s PF00428.14 OAJ23871.1 - 0.00069 19.9 3.9 0.00069 19.9 2.7 6.3 7 0 0 7 7 7 1 60s Acidic ribosomal protein DUF3608 PF12257.3 OAJ23872.1 - 1.3e-66 224.4 0.0 3.9e-45 153.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3608) DEP PF00610.16 OAJ23872.1 - 1.7e-16 59.7 0.1 5.4e-16 58.1 0.1 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ACBP PF00887.14 OAJ23873.1 - 3.4e-32 109.9 0.2 4.9e-32 109.4 0.1 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Tox-REase-5 PF15648.1 OAJ23873.1 - 0.063 13.5 0.6 0.085 13.1 0.4 1.3 1 1 0 1 1 1 0 Restriction endonuclease fold toxin 5 COX6B PF02297.12 OAJ23874.1 - 1.2e-19 70.0 8.7 1.5e-19 69.8 6.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 OAJ23874.1 - 0.083 12.8 0.4 0.25 11.3 0.3 1.9 1 1 0 1 1 1 0 CHCH domain UCR_hinge PF02320.11 OAJ23874.1 - 0.14 12.1 0.5 0.14 12.1 0.4 1.9 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 OAJ23874.1 - 0.98 9.3 8.0 3 7.7 0.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) DUF221 PF02714.10 OAJ23875.1 - 7e-98 327.4 18.0 1e-97 326.9 12.5 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAJ23875.1 - 5e-35 120.3 2.2 5e-35 120.3 1.5 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 OAJ23875.1 - 3.5e-20 72.3 1.9 5.6e-20 71.6 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 OAJ23875.1 - 4.4e-13 48.9 0.0 1.1e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein Abhydrolase_5 PF12695.2 OAJ23876.1 - 1.4e-06 28.1 0.1 6.4e-06 25.9 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ23876.1 - 3.1e-06 27.2 2.0 4.8e-06 26.6 1.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 OAJ23876.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.13 OAJ23876.1 - 0.052 12.8 0.0 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family Phage_integrase PF00589.17 OAJ23877.1 - 4.7e-06 26.3 0.0 7.3e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Phage integrase family RVT_2 PF07727.9 OAJ23878.1 - 3.7e-85 284.8 0.0 5.1e-85 284.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ23878.1 - 1.8e-24 86.1 0.1 4.7e-24 84.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain UBN2 PF14223.1 OAJ23878.1 - 4e-05 23.3 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 OAJ23878.1 - 0.00042 19.7 0.0 0.00096 18.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ23878.1 - 0.0015 18.1 0.1 0.0052 16.3 0.1 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain Transcript_VP30 PF11507.3 OAJ23878.1 - 0.038 13.8 0.5 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 Ebola virus-specific transcription factor VP30 RVT_1 PF00078.22 OAJ23878.1 - 0.21 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Porin_3 PF01459.17 OAJ23879.1 - 9.1e-61 205.5 0.5 1e-60 205.3 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin Rrp15p PF07890.7 OAJ23880.1 - 9e-27 93.6 0.5 9e-27 93.6 0.4 2.4 2 1 0 2 2 2 1 Rrp15p Daxx PF03344.10 OAJ23880.1 - 0.013 14.0 12.0 0.018 13.5 8.3 1.3 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 OAJ23880.1 - 0.026 12.8 20.6 0.047 12.0 14.3 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YL1 PF05764.8 OAJ23880.1 - 0.34 10.4 22.8 0.92 9.0 15.8 1.7 1 1 0 1 1 1 0 YL1 nuclear protein DUF3295 PF11702.3 OAJ23880.1 - 0.53 9.2 9.5 0.91 8.4 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Ebola_NP PF05505.7 OAJ23880.1 - 0.84 7.6 11.1 1.3 7.0 7.7 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein Med17 PF10156.4 OAJ23880.1 - 1.2 7.2 7.3 5.1 5.2 0.0 2.1 2 0 0 2 2 2 0 Subunit 17 of Mediator complex BUD22 PF09073.5 OAJ23880.1 - 1.7 7.6 25.8 0.35 9.9 12.3 2.2 2 0 0 2 2 2 0 BUD22 CDC45 PF02724.9 OAJ23880.1 - 7.6 4.4 19.6 1.5 6.8 10.6 1.7 2 0 0 2 2 2 0 CDC45-like protein Mpp10 PF04006.7 OAJ23880.1 - 7.9 4.7 20.9 17 3.5 14.5 1.4 1 0 0 1 1 1 0 Mpp10 protein Myc_N PF01056.13 OAJ23880.1 - 9.9 5.2 17.2 1.5e+04 -5.4 11.9 2.5 1 1 0 1 1 0 0 Myc amino-terminal region PMT PF02366.13 OAJ23882.1 - 1e-36 126.5 18.6 1e-36 126.5 12.9 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 OAJ23882.1 - 2.1e-30 105.6 0.1 3.7e-30 104.8 0.1 1.4 1 0 0 1 1 1 1 MIR domain Pro-kuma_activ PF09286.6 OAJ23883.1 - 3.3e-16 59.6 0.0 6.3e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 OAJ23883.1 - 1e-13 51.0 6.4 1e-13 51.0 4.5 1.6 2 0 0 2 2 2 1 Subtilase family PhoPQ_related PF10142.4 OAJ23883.1 - 0.14 10.5 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein HisG_C PF08029.6 OAJ23884.1 - 0.036 14.0 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 HisG, C-terminal domain YlaH PF14036.1 OAJ23884.1 - 0.044 13.8 0.7 0.044 13.8 0.5 2.1 3 0 0 3 3 3 0 YlaH-like protein PMT_2 PF13231.1 OAJ23884.1 - 2 8.2 10.5 1.9 8.3 3.2 2.4 2 1 1 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase LIP PF03583.9 OAJ23893.1 - 6.8e-46 156.7 0.3 8.1e-45 153.2 0.2 2.0 1 1 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.16 OAJ23893.1 - 0.0099 15.1 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Cutinase PF01083.17 OAJ23893.1 - 0.091 12.4 0.1 0.26 11.0 0.1 1.8 1 0 0 1 1 1 0 Cutinase SPRY PF00622.23 OAJ23894.1 - 5.6e-05 23.2 0.0 0.0057 16.7 0.0 3.3 3 0 0 3 3 3 1 SPRY domain CUE PF02845.11 OAJ23896.1 - 1.2e-12 47.0 0.1 2e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 CUE domain MFS_1 PF07690.11 OAJ23897.1 - 4.5e-06 25.6 25.6 8.7e-06 24.6 17.8 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 OAJ23897.1 - 0.00011 21.7 5.5 0.00011 21.7 3.8 2.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 ComJ PF11033.3 OAJ23897.1 - 0.03 13.9 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Competence protein J (ComJ) eIF3g PF12353.3 OAJ23898.1 - 1.3e-40 138.2 1.4 2.2e-40 137.5 1.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 OAJ23898.1 - 2.9e-18 65.2 0.0 4.7e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ23898.1 - 3.7e-15 55.6 0.0 6.6e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ23898.1 - 1.4e-08 34.4 0.0 2.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Toxin_ToxA PF11584.3 OAJ23898.1 - 0.017 14.9 0.0 4.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Proteinaceous host-selective toxin ToxA MerB PF03243.10 OAJ23898.1 - 0.12 12.2 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Alkylmercury lyase Svf1 PF08622.5 OAJ23899.1 - 3.6e-85 285.8 0.0 7.4e-85 284.7 0.0 1.5 1 1 0 1 1 1 1 Svf1-like Spc97_Spc98 PF04130.8 OAJ23900.1 - 1.3e-65 221.8 0.0 1.6e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Activator_LAG-3 PF11498.3 OAJ23900.1 - 5.9 5.5 23.2 9.7 4.8 16.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4557 PF15101.1 OAJ23900.1 - 7.8 6.2 8.5 14 5.4 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) TFIIA_gamma_N PF02268.11 OAJ23901.1 - 9e-26 89.2 0.1 1.2e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 OAJ23901.1 - 7.6e-23 80.0 0.3 1e-22 79.6 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DUF2414 PF10309.4 OAJ23902.1 - 8.5e-05 22.1 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 OAJ23902.1 - 0.00012 21.9 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain RRM_3 PF08777.6 OAJ23902.1 - 0.033 14.0 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif La PF05383.12 OAJ23903.1 - 2.5e-12 46.3 0.1 1e-05 25.1 0.3 2.5 2 0 0 2 2 2 2 La domain RRM_1 PF00076.17 OAJ23903.1 - 2e-06 27.3 0.1 4.4e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ23903.1 - 8.9e-05 22.3 0.0 0.00021 21.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ23903.1 - 0.021 14.6 0.0 0.065 13.1 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyt-b5 PF00173.23 OAJ23904.1 - 1.4e-23 82.5 0.2 1.5e-23 82.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 OAJ23904.1 - 0.04 13.8 0.0 0.08 12.8 0.0 1.5 1 1 0 1 1 1 0 V-ATPase subunit H HlyIII PF03006.15 OAJ23905.1 - 4.8e-50 170.0 21.1 6e-50 169.7 14.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related ABC2_membrane_5 PF13346.1 OAJ23905.1 - 0.47 9.7 7.0 0.37 10.0 3.3 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Arrestin_C PF02752.17 OAJ23906.1 - 1.5e-05 25.1 0.0 4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 OAJ23906.1 - 0.0011 18.8 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain MFS_1 PF07690.11 OAJ23909.1 - 4.5e-36 124.2 12.0 6.8e-36 123.6 8.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CTD_bind PF04818.8 OAJ23910.1 - 0.0003 20.9 0.0 0.022 14.9 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Mito_fiss_reg PF05308.6 OAJ23910.1 - 3.9 6.7 9.1 9.3 5.5 6.3 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator Pkinase PF00069.20 OAJ23914.1 - 1.1e-60 204.9 0.0 9.9e-59 198.5 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ23914.1 - 2e-22 79.5 0.0 1.7e-20 73.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ23914.1 - 1.2e-05 24.3 0.0 2.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ23914.1 - 0.0065 16.2 0.1 0.038 13.7 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAJ23914.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase CDK2AP PF09806.4 OAJ23914.1 - 0.028 14.6 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3138 PF11336.3 OAJ23914.1 - 0.034 12.3 3.4 0.046 11.8 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1679 PF07914.6 OAJ23914.1 - 0.067 11.8 0.5 0.15 10.6 0.3 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) D123 PF07065.9 OAJ23915.1 - 1.8e-62 211.1 0.0 5.5e-62 209.5 0.0 1.8 1 1 0 1 1 1 1 D123 Ofd1_CTDD PF10637.4 OAJ23916.1 - 3.1e-88 295.3 0.0 3e-82 275.7 0.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 OAJ23916.1 - 1.5e-17 63.9 0.1 3.3e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BUD22 PF09073.5 OAJ23916.1 - 0.8 8.7 12.3 1.7 7.6 8.5 1.5 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 OAJ23916.1 - 1.7 6.4 13.5 2.7 5.7 9.4 1.2 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 OAJ23916.1 - 4.1 7.0 9.2 9.4 5.8 6.4 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1212 PF06738.7 OAJ23917.1 - 2.8e-39 134.5 1.0 2.8e-39 134.5 0.7 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 OAJ23917.1 - 3.8e-17 62.4 8.3 3.8e-17 62.4 5.7 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3815) F-box PF00646.28 OAJ23918.1 - 1.5e-07 30.8 1.7 2.5e-07 30.1 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 OAJ23918.1 - 0.0012 18.5 0.5 0.0041 16.8 0.1 2.0 2 0 0 2 2 2 1 F-box-like UDPGT PF00201.13 OAJ23919.1 - 1.6e-13 50.0 0.0 2.2e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Helicase_C PF00271.26 OAJ23921.1 - 1.6e-20 72.7 0.1 1.7e-19 69.4 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ23921.1 - 2.4e-18 66.6 0.0 6.5e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ23921.1 - 6e-18 64.9 0.0 1.3e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ACT PF01842.20 OAJ23921.1 - 0.1 12.0 0.2 0.46 10.0 0.2 2.1 1 0 0 1 1 1 0 ACT domain WD40 PF00400.27 OAJ23922.1 - 8.4e-08 31.8 14.6 0.0058 16.4 2.6 5.6 5 1 0 5 5 5 2 WD domain, G-beta repeat Equine_IAV_S2 PF06502.6 OAJ23922.1 - 0.067 13.0 0.2 0.38 10.6 0.0 2.3 2 0 0 2 2 2 0 Equine infectious anaemia virus S2 protein SCP2 PF02036.12 OAJ23923.1 - 4.6e-16 58.9 0.0 7.6e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family zf-AN1 PF01428.11 OAJ23924.1 - 3.9e-15 55.4 21.4 1.3e-10 40.9 3.6 3.1 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 OAJ23924.1 - 0.014 15.5 14.0 0.32 11.2 1.9 3.2 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain C1_4 PF07975.7 OAJ23924.1 - 0.72 9.8 9.6 2.1 8.4 0.4 2.9 2 0 0 2 2 2 0 TFIIH C1-like domain IBR PF01485.16 OAJ23924.1 - 2.9 7.8 16.8 2.1 8.3 3.3 3.0 2 1 0 2 2 2 0 IBR domain zf-trcl PF13451.1 OAJ23924.1 - 3 7.5 6.9 8.3 6.1 0.5 2.6 2 0 0 2 2 2 0 Probable zinc-binding domain RCC1 PF00415.13 OAJ23925.1 - 1.7e-16 60.1 8.1 0.00066 19.8 0.0 7.5 7 2 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ23925.1 - 5.5e-16 57.7 8.2 0.00018 20.9 0.1 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat CarbpepA_inh PF02977.10 OAJ23926.1 - 0.025 14.1 1.7 0.025 14.1 1.2 1.8 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Hydrophobin PF01185.13 OAJ23926.1 - 0.027 14.9 5.6 0.15 12.5 3.9 1.9 1 1 0 1 1 1 0 Fungal hydrophobin Aminotran_1_2 PF00155.16 OAJ23927.1 - 3.2e-58 197.4 0.0 4.2e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-Tim10_DDP PF02953.10 OAJ23928.1 - 2.9e-19 68.0 2.1 3.7e-19 67.7 1.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Flagellin_N PF00669.15 OAJ23928.1 - 0.02 14.6 0.2 0.026 14.3 0.1 1.1 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region FANCI_S3 PF14677.1 OAJ23928.1 - 0.075 12.4 0.3 0.091 12.1 0.2 1.2 1 0 0 1 1 1 0 FANCI solenoid 3 RR_TM4-6 PF06459.7 OAJ23929.1 - 0.41 10.4 5.2 0.88 9.4 3.6 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WD40 PF00400.27 OAJ23930.1 - 7.9e-17 60.4 9.1 1.9e-06 27.5 0.1 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ArfGap PF01412.13 OAJ23931.1 - 2.9e-32 110.9 0.4 5.2e-32 110.0 0.3 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 OAJ23931.1 - 7.7e-08 32.4 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF1724 PF08350.5 OAJ23931.1 - 0.52 9.8 0.2 1 8.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) FAD_binding_4 PF01565.18 OAJ23932.1 - 1.5e-13 50.3 1.6 2.8e-13 49.5 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAJ23932.1 - 7.6e-09 35.3 0.5 1.9e-08 34.0 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like Mito_carr PF00153.22 OAJ23938.1 - 3e-62 206.3 4.6 5e-21 74.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.26 OAJ23939.1 - 9.5e-23 79.7 1.1 1.5e-22 79.0 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain Acid_PPase PF12689.2 OAJ23940.1 - 4.7e-55 185.7 0.0 5.6e-55 185.5 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 OAJ23940.1 - 4.9e-06 26.8 0.4 4.2e-05 23.8 0.0 2.2 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase NIF PF03031.13 OAJ23940.1 - 0.00041 20.0 0.0 0.00058 19.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RGS PF00615.14 OAJ23941.1 - 1.1e-35 122.2 0.1 3.4e-25 88.4 0.0 3.6 3 1 0 3 3 3 2 Regulator of G protein signaling domain DEP PF00610.16 OAJ23941.1 - 1.8e-14 53.2 0.0 1.4e-07 31.1 0.0 2.7 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Hist_deacetyl PF00850.14 OAJ23942.1 - 2.6e-92 309.4 0.1 3.8e-92 308.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 OAJ23942.1 - 3.6e-15 55.8 0.0 6.8e-14 51.6 0.0 2.2 2 0 0 2 2 2 1 Arb2 domain DPBB_1 PF03330.13 OAJ23943.1 - 6.9e-11 41.9 0.6 1.9e-10 40.5 0.4 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 OAJ23943.1 - 0.0054 16.7 0.6 0.025 14.5 0.0 2.2 2 0 0 2 2 2 1 Cerato-platanin Nop14 PF04147.7 OAJ23943.1 - 0.0081 14.1 19.2 0.01 13.8 13.3 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.4 OAJ23943.1 - 0.0082 14.9 21.4 0.011 14.4 14.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Daxx PF03344.10 OAJ23943.1 - 0.018 13.5 13.3 0.022 13.2 9.2 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 OAJ23943.1 - 0.043 13.0 12.5 0.054 12.7 8.6 1.2 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.8 OAJ23943.1 - 0.13 12.1 26.7 0.012 15.4 15.0 1.7 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.7 OAJ23943.1 - 0.81 9.3 15.7 1.3 8.7 10.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.7 OAJ23943.1 - 1.1 8.4 18.5 1.7 7.8 12.9 1.2 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.11 OAJ23943.1 - 1.7 7.5 14.4 2.8 6.8 10.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPP4R2 PF09184.6 OAJ23943.1 - 2.1 7.7 19.7 3.4 7.1 13.7 1.3 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.5 OAJ23943.1 - 6.2 5.7 18.0 8.6 5.3 12.5 1.2 1 0 0 1 1 1 0 BUD22 EF_assoc_1 PF08355.7 OAJ23944.1 - 0.00028 20.1 0.0 0.0005 19.3 0.0 1.4 1 0 0 1 1 1 1 EF hand associated Daxx PF03344.10 OAJ23944.1 - 0.031 12.7 5.3 0.049 12.1 3.7 1.3 1 0 0 1 1 1 0 Daxx Family DUF572 PF04502.8 OAJ23944.1 - 0.063 12.4 2.2 0.088 12.0 1.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Nop14 PF04147.7 OAJ23944.1 - 0.066 11.1 4.3 0.081 10.8 3.0 1.1 1 0 0 1 1 1 0 Nop14-like family Pol_alpha_B_N PF08418.5 OAJ23944.1 - 0.066 12.7 4.4 0.1 12.1 3.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Synaphin PF05835.7 OAJ23944.1 - 0.46 10.6 7.3 0.83 9.8 5.1 1.3 1 0 0 1 1 1 0 Synaphin protein DUF605 PF04652.11 OAJ23944.1 - 2.6 7.3 15.4 3.5 6.9 10.6 1.1 1 0 0 1 1 1 0 Vta1 like CDC45 PF02724.9 OAJ23944.1 - 3.1 5.7 5.1 3.8 5.4 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Rb_C PF08934.5 OAJ23945.1 - 0.08 12.5 0.6 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Rb C-terminal domain TSA PF03249.8 OAJ23946.1 - 0.052 12.0 5.5 0.077 11.5 3.8 1.2 1 0 0 1 1 1 0 Type specific antigen Macoilin PF09726.4 OAJ23946.1 - 0.37 9.0 6.4 0.44 8.7 4.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Dmrt1 PF12374.3 OAJ23946.1 - 9.9 6.6 21.5 2.3 8.6 7.4 2.4 1 1 1 2 2 2 0 Double-sex mab3 related transcription factor 1 Nitroreductase PF00881.19 OAJ23947.1 - 2.2e-11 43.8 0.0 2.7e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family YodL PF14191.1 OAJ23947.1 - 0.043 14.3 0.0 0.091 13.2 0.0 1.5 1 0 0 1 1 1 0 YodL-like DUF1688 PF07958.6 OAJ23948.1 - 1.3e-142 475.2 0.0 5.7e-92 308.4 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1688) HK PF02110.10 OAJ23949.1 - 2e-58 197.4 8.5 6.8e-57 192.4 4.3 2.5 2 1 0 3 3 3 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 OAJ23949.1 - 1.1e-43 148.4 0.1 1.6e-42 144.6 0.0 2.2 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 OAJ23949.1 - 1.2e-07 31.1 0.8 2e-07 30.4 0.6 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Actin PF00022.14 OAJ23950.1 - 4.2e-30 104.4 0.0 2.2e-19 69.1 0.0 3.6 3 1 0 3 3 3 2 Actin Sporozoite_P67 PF05642.6 OAJ23950.1 - 0.9 7.3 9.3 0.15 9.9 3.3 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen bZIP_1 PF00170.16 OAJ23951.1 - 9.6e-06 25.4 5.0 2.4e-05 24.1 3.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAJ23951.1 - 5.3e-05 22.9 4.7 0.00013 21.7 3.3 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Herpes_BLRF2 PF05812.7 OAJ23951.1 - 0.0003 20.5 0.4 0.00066 19.4 0.3 1.6 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein Myosin_tail_1 PF01576.14 OAJ23951.1 - 0.021 12.5 2.9 0.029 12.1 2.0 1.1 1 0 0 1 1 1 0 Myosin tail Leu_zip PF15294.1 OAJ23951.1 - 0.045 12.8 0.2 0.07 12.2 0.1 1.2 1 0 0 1 1 1 0 Leucine zipper Allexi_40kDa PF05549.6 OAJ23951.1 - 0.058 12.6 0.9 0.17 11.1 0.6 1.8 1 0 0 1 1 1 0 Allexivirus 40kDa protein AATF-Che1 PF13339.1 OAJ23951.1 - 0.14 12.3 3.1 0.42 10.7 2.1 1.9 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF3584 PF12128.3 OAJ23951.1 - 0.51 7.6 2.8 0.74 7.0 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Pkinase PF00069.20 OAJ23952.1 - 1.1e-59 201.6 0.0 1.4e-39 135.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ23952.1 - 6.6e-26 90.9 0.0 8.3e-21 74.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 OAJ23952.1 - 5.9e-09 35.9 0.1 1e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 OAJ23952.1 - 5.9e-07 28.7 0.4 1.2e-05 24.4 0.0 2.4 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 OAJ23952.1 - 0.00098 18.9 0.0 0.017 14.8 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ23952.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PAS_4 PF08448.5 OAJ23952.1 - 0.017 15.1 0.0 0.06 13.3 0.0 1.9 1 0 0 1 1 1 0 PAS fold Kdo PF06293.9 OAJ23952.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OKR_DC_1_N PF03709.10 OAJ23952.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain PALP PF00291.20 OAJ23953.1 - 1.6e-48 165.5 2.7 6.7e-48 163.4 1.9 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.10 OAJ23953.1 - 0.059 12.9 0.4 0.13 11.8 0.3 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein RVT_1 PF00078.22 OAJ23954.1 - 8.1e-19 67.8 0.0 1.5e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ23954.1 - 3.2e-15 56.3 0.0 8.5e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ23954.1 - 0.00075 19.9 0.0 0.0019 18.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ23954.1 - 0.0065 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ23954.1 - 0.024 14.4 0.1 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease NCA2 PF08637.5 OAJ23960.1 - 1.7e-72 243.8 0.0 3.4e-72 242.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Nrap PF03813.9 OAJ23961.1 - 8.9e-235 781.5 0.0 1.1e-234 781.2 0.0 1.0 1 0 0 1 1 1 1 Nrap protein Nop14 PF04147.7 OAJ23961.1 - 0.0011 16.9 23.3 0.0017 16.4 16.1 1.1 1 0 0 1 1 1 1 Nop14-like family DUF2890 PF11081.3 OAJ23961.1 - 0.16 12.0 10.0 0.4 10.7 6.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 OAJ23961.1 - 1.1 7.6 23.4 1.7 7.0 16.2 1.2 1 0 0 1 1 1 0 Daxx Family eIF3_subunit PF08597.5 OAJ23961.1 - 1.4 8.4 21.2 1 8.8 5.9 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit SDA1 PF05285.7 OAJ23961.1 - 7.8 5.6 24.0 14 4.8 16.6 1.3 1 0 0 1 1 1 0 SDA1 FAD-oxidase_C PF02913.14 OAJ23962.1 - 6.1e-51 173.1 0.0 1.2e-50 172.1 0.0 1.5 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 OAJ23962.1 - 3.1e-26 91.5 0.0 2e-25 88.8 0.0 2.4 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.7 OAJ23962.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like DHHW PF14286.1 OAJ23963.1 - 0.2 10.9 1.3 0.6 9.3 0.5 1.8 2 0 0 2 2 2 0 DHHW protein DUF1168 PF06658.7 OAJ23963.1 - 2.2 7.8 9.1 0.13 11.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) RAP1 PF07218.6 OAJ23963.1 - 6.1 4.8 13.3 6.5 4.7 9.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Acyl-thio_N PF12590.3 OAJ23963.1 - 8.1 6.9 10.3 0.083 13.3 1.3 1.9 3 0 0 3 3 3 0 Acyl-ATP thioesterase ABC_membrane PF00664.18 OAJ23967.1 - 3.4e-58 197.2 21.3 2.7e-32 112.2 6.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ23967.1 - 2.3e-50 170.4 0.0 4.5e-26 91.7 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 OAJ23967.1 - 4.1e-07 29.4 0.1 0.016 14.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 OAJ23967.1 - 3.2e-06 27.6 0.1 0.15 12.5 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_21 PF13304.1 OAJ23967.1 - 5e-06 26.6 0.0 0.76 9.6 0.0 4.2 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 OAJ23967.1 - 6.4e-06 26.1 0.0 0.15 11.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 OAJ23967.1 - 7.1e-06 25.5 0.1 0.019 14.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 OAJ23967.1 - 8.2e-06 25.2 1.5 0.55 9.4 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 OAJ23967.1 - 6.8e-05 22.9 1.8 0.15 11.9 0.0 3.6 3 1 1 4 4 4 2 AAA ATPase domain DUF258 PF03193.11 OAJ23967.1 - 0.00067 18.8 0.6 0.27 10.4 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 OAJ23967.1 - 0.0022 18.3 7.2 0.088 13.1 0.0 3.6 4 0 0 4 4 3 1 AAA domain Dynamin_N PF00350.18 OAJ23967.1 - 0.0031 17.3 4.3 0.43 10.3 0.0 3.1 3 0 0 3 3 2 2 Dynamin family AAA_17 PF13207.1 OAJ23967.1 - 0.0031 18.2 0.0 2.6 8.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 OAJ23967.1 - 0.0048 16.0 1.4 0.52 9.3 0.3 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 OAJ23967.1 - 0.0085 16.3 0.4 3.5 7.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 OAJ23967.1 - 0.017 14.7 0.1 7.9 6.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 OAJ23967.1 - 0.03 13.7 0.1 3.6 6.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.1 OAJ23967.1 - 0.12 11.3 3.0 0.31 10.0 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain Arch_ATPase PF01637.13 OAJ23967.1 - 0.32 10.6 0.0 0.32 10.6 0.0 2.9 4 0 0 4 4 2 0 Archaeal ATPase PIF1 PF05970.9 OAJ23968.1 - 2.3e-59 201.1 0.6 2.4e-46 158.3 0.1 2.1 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 OAJ23968.1 - 2.6e-17 63.0 0.0 4.8e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ23968.1 - 4.3e-08 33.3 0.0 8.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ23968.1 - 0.00018 21.2 0.7 0.00044 19.9 0.5 1.6 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 OAJ23968.1 - 0.00031 20.8 0.0 0.0063 16.6 0.0 2.6 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 OAJ23968.1 - 0.00042 19.8 0.1 0.47 9.9 0.1 3.1 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 OAJ23968.1 - 0.00053 18.9 0.0 0.00088 18.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 OAJ23968.1 - 0.0011 18.0 0.0 0.0021 17.0 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 OAJ23968.1 - 0.0011 19.0 0.1 0.0037 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain TrwB_AAD_bind PF10412.4 OAJ23968.1 - 0.0026 16.4 0.0 0.0047 15.5 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.24 OAJ23968.1 - 0.0041 17.3 0.0 0.009 16.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 OAJ23968.1 - 0.0056 16.2 0.1 0.53 9.8 0.0 2.6 1 1 1 2 2 2 1 AAA domain PhoH PF02562.11 OAJ23968.1 - 0.01 15.0 0.0 0.025 13.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 OAJ23968.1 - 0.011 15.4 0.0 0.028 14.0 0.0 1.8 1 1 0 1 1 1 0 NACHT domain Herpes_Helicase PF02689.9 OAJ23968.1 - 0.013 13.2 0.1 0.31 8.7 0.0 2.2 2 0 0 2 2 2 0 Helicase AAA_14 PF13173.1 OAJ23968.1 - 0.014 15.3 0.0 0.084 12.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 OAJ23968.1 - 0.017 14.8 0.1 0.088 12.4 0.1 2.0 1 1 0 1 1 1 0 Archaeal ATPase IstB_IS21 PF01695.12 OAJ23968.1 - 0.023 14.1 0.0 2.9 7.2 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.2 OAJ23968.1 - 0.065 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 Sigma54_activat PF00158.21 OAJ23968.1 - 0.072 12.5 0.1 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 OAJ23968.1 - 0.089 12.5 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 OAJ23968.1 - 0.12 12.0 0.2 0.97 9.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) HTH_17 PF12728.2 OAJ23968.1 - 0.13 12.4 0.1 9.8 6.5 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain NAD_kinase PF01513.16 OAJ23969.1 - 1.3e-51 175.0 0.0 1.6e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase E1-E2_ATPase PF00122.15 OAJ23970.1 - 8.2e-26 90.4 0.1 6.1e-25 87.5 0.1 2.2 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 OAJ23970.1 - 1.2e-25 90.8 0.8 1.7e-25 90.3 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 OAJ23970.1 - 5.6e-25 87.5 0.0 1.5e-24 86.1 0.0 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.21 OAJ23970.1 - 9.9e-22 78.4 0.0 4.9e-20 72.8 0.0 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 OAJ23970.1 - 6.5e-06 25.7 10.0 6.5e-06 25.7 6.9 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 OAJ23970.1 - 8.9e-05 22.3 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAJ23970.1 - 0.021 14.4 0.0 0.11 12.1 0.0 2.1 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAJ23970.1 - 0.021 14.2 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus RskA PF10099.4 OAJ23971.1 - 0.053 13.2 5.1 0.16 11.7 1.4 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA F5_F8_type_C PF00754.20 OAJ23971.1 - 0.15 11.9 1.3 1.9 8.3 0.0 3.3 5 0 0 5 5 5 0 F5/8 type C domain BNR PF02012.15 OAJ23971.1 - 5.5 7.2 27.9 15 5.9 0.0 6.6 6 0 0 6 6 6 0 BNR/Asp-box repeat NPR3 PF03666.8 OAJ23973.1 - 1.2e-70 238.3 6.1 5.7e-40 137.2 0.0 3.5 3 0 0 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 OAJ23973.1 - 0.17 10.5 0.0 3.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Nitrogen permease regulator 2 PTPLA PF04387.9 OAJ23974.1 - 4.4e-48 162.8 5.1 4.4e-48 162.8 3.5 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA DUF1649 PF07855.7 OAJ23975.1 - 3.7e-15 55.9 0.0 3.1e-14 52.9 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1649) Ribosomal_L18e PF00828.14 OAJ23976.1 - 2.7e-20 73.0 0.0 4.2e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Romo1 PF10247.4 OAJ23982.1 - 4.6e-20 71.5 12.3 6.8e-20 71.0 8.6 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_OmpA PF13436.1 OAJ23982.1 - 0.011 15.3 2.4 0.016 14.8 1.4 1.5 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain NDT80_PhoG PF05224.7 OAJ23982.1 - 0.023 14.7 0.0 0.023 14.7 0.0 1.1 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family Ndc1_Nup PF09531.5 OAJ23982.1 - 0.043 12.2 0.2 0.042 12.2 0.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1183 PF06682.7 OAJ23982.1 - 0.53 9.8 3.0 0.62 9.6 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF605 PF04652.11 OAJ23982.1 - 4.1 6.7 17.6 4.9 6.4 12.2 1.0 1 0 0 1 1 1 0 Vta1 like Peptidase_M28 PF04389.12 OAJ23983.1 - 1.5e-32 112.7 0.0 2.7e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 DOT1 PF08123.8 OAJ23985.1 - 5.1e-65 218.6 0.0 6.9e-65 218.1 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 ABC_membrane PF00664.18 OAJ23987.1 - 6.1e-47 160.3 1.5 7.9e-47 159.9 1.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ23987.1 - 1.4e-31 109.6 0.0 4.2e-31 108.0 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 OAJ23987.1 - 0.00018 21.5 0.0 0.037 14.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ23987.1 - 0.00031 20.7 0.1 0.0016 18.4 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 OAJ23987.1 - 0.0014 17.9 0.6 0.041 13.0 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF637 PF04830.8 OAJ23987.1 - 0.0024 17.5 0.2 0.0075 15.9 0.1 1.8 1 0 0 1 1 1 1 Possible hemagglutinin (DUF637) AAA PF00004.24 OAJ23987.1 - 0.0049 17.0 0.0 0.084 13.0 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ23987.1 - 0.0065 16.6 0.1 0.046 13.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 OAJ23987.1 - 0.0069 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 OAJ23987.1 - 0.012 14.2 0.0 0.02 13.4 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_5 PF07728.9 OAJ23987.1 - 0.035 13.8 0.0 0.63 9.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 OAJ23987.1 - 0.055 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 OAJ23987.1 - 0.081 12.0 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 OAJ23987.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_polI_A34 PF08208.6 OAJ23988.1 - 0.021 14.5 45.9 6e+02 -0.1 31.8 3.1 1 1 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 BMF PF15185.1 OAJ23988.1 - 0.41 9.8 9.6 0.036 13.3 0.4 2.4 2 1 0 2 2 2 0 Bcl-2-modifying factor, apoptosis HMG_box PF00505.14 OAJ23989.1 - 1.6e-11 44.2 0.3 2.9e-11 43.4 0.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ23989.1 - 1.4e-10 41.4 0.2 2.7e-10 40.4 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain PXA PF02194.10 OAJ23991.1 - 1.4e-13 50.8 0.0 3.4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 OAJ23991.1 - 5.3e-07 29.7 0.0 1.2e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Sorting nexin C terminal DUF2273 PF10031.4 OAJ23991.1 - 0.11 12.1 1.8 0.19 11.3 1.3 1.3 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) DSPc PF00782.15 OAJ23992.1 - 5.3e-16 58.4 0.0 2.4e-14 53.0 0.2 2.6 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAJ23992.1 - 0.014 14.7 0.1 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase GOLD_2 PF13897.1 OAJ23992.1 - 1.1 9.4 1.8 2.3 8.4 0.5 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking WD40 PF00400.27 OAJ23993.1 - 8.3e-12 44.5 1.5 0.00071 19.3 0.2 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat 5_nucleotid_C PF02872.13 OAJ23993.1 - 0.014 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain CENP-F_leu_zip PF10473.4 OAJ23994.1 - 0.0014 18.4 0.7 0.002 17.9 0.5 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3166 PF11365.3 OAJ23994.1 - 0.0054 17.1 0.4 0.014 15.8 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3166) APG6 PF04111.7 OAJ23994.1 - 0.032 13.2 2.3 0.041 12.9 1.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Herpes_UL6 PF01763.11 OAJ23994.1 - 0.041 12.0 0.2 0.042 12.0 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like RDM PF11002.3 OAJ23994.1 - 0.05 13.2 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 RFPL defining motif (RDM) DivIC PF04977.10 OAJ23994.1 - 0.071 12.6 4.7 0.15 11.5 3.2 1.5 1 1 0 1 1 1 0 Septum formation initiator Blo-t-5 PF11642.3 OAJ23994.1 - 0.12 12.0 3.1 0.17 11.6 2.2 1.2 1 0 0 1 1 1 0 Mite allergen Blo t 5 adh_short PF00106.20 OAJ23996.1 - 3.1e-11 43.4 8.1 1e-06 28.8 1.9 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 OAJ23996.1 - 3.3e-06 26.8 5.1 5e-05 23.0 0.7 2.3 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 OAJ23996.1 - 0.0016 18.2 0.7 0.36 10.5 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase TPR_12 PF13424.1 OAJ23997.1 - 3.2e-05 23.7 0.0 0.00067 19.5 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc5 PF12862.2 OAJ23997.1 - 0.085 12.7 0.3 0.35 10.7 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 Myotub-related PF06602.9 OAJ23998.1 - 2.4e-120 401.5 0.0 6.8e-66 222.4 0.0 2.1 2 0 0 2 2 2 2 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 OAJ23998.1 - 0.072 13.3 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 OAJ23998.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase UCH PF00443.24 OAJ23999.1 - 1.7e-49 168.3 0.0 1.3e-48 165.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ23999.1 - 3.2e-19 69.4 0.4 2.4e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 OAJ23999.1 - 1.1e-08 35.0 1.0 1.1e-08 35.0 0.7 3.2 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein PBP1_TM PF14812.1 OAJ23999.1 - 0.84 9.9 17.4 0.21 11.9 5.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 OAJ23999.1 - 1.8 8.0 13.0 3.2 7.2 6.0 2.3 2 0 0 2 2 2 0 Nucleoplasmin RabGAP-TBC PF00566.13 OAJ24000.1 - 7.4e-43 146.5 0.2 9.9e-43 146.0 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EB PF01683.13 OAJ24005.1 - 1.4 9.0 31.7 0.25 11.4 3.2 4.1 3 3 0 3 3 3 0 EB module DUF4231 PF14015.1 OAJ24006.1 - 0.0042 17.0 0.9 0.3 11.0 0.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4231) DUF2721 PF11026.3 OAJ24006.1 - 0.065 12.8 0.2 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF2207 PF09972.4 OAJ24006.1 - 0.14 10.6 3.4 1.1 7.8 0.0 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Sporozoite_P67 PF05642.6 OAJ24007.1 - 1.2 6.9 10.4 1.4 6.6 7.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRF PF01765.14 OAJ24008.1 - 4.5e-33 114.0 0.1 8.2e-33 113.1 0.1 1.4 1 0 0 1 1 1 1 Ribosome recycling factor Acyl-CoA_dh_C PF12806.2 OAJ24008.1 - 0.018 14.8 0.5 3.5 7.4 0.0 2.7 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like DUF3682 PF12446.3 OAJ24009.1 - 0.0094 16.2 0.1 0.011 16.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3682) HCMVantigenic_N PF12154.3 OAJ24009.1 - 0.019 14.8 6.4 0.031 14.1 4.4 1.4 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV Corona_nucleoca PF00937.13 OAJ24009.1 - 0.064 12.1 0.8 0.081 11.8 0.5 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF3446 PF11928.3 OAJ24009.1 - 0.12 12.5 3.3 0.23 11.7 1.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3446) VCBS PF13517.1 OAJ24011.1 - 9.1e-21 73.9 14.3 2e-06 28.0 0.4 5.8 3 2 3 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 OAJ24011.1 - 1.4e-13 50.1 8.3 0.00036 20.1 0.1 5.9 5 1 0 5 5 5 5 FG-GAP repeat TcdB_toxin_midN PF12256.3 OAJ24011.1 - 1.3e-05 24.6 1.1 8.6 5.7 0.0 5.2 5 0 0 5 5 5 3 Insecticide toxin TcdB middle/N-terminal region zf-CCHC PF00098.18 OAJ24012.1 - 1.3e-48 160.7 58.8 3.6e-07 29.8 3.2 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ24012.1 - 7.2e-11 41.6 31.5 0.069 12.8 0.7 7.0 4 2 3 7 7 7 6 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ24012.1 - 3.6e-10 39.3 44.4 0.014 15.0 1.2 7.0 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.1 OAJ24012.1 - 4.6e-05 23.0 14.4 0.0015 18.1 1.3 7.0 5 2 2 7 7 7 4 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ24012.1 - 0.07 12.6 0.1 0.07 12.6 0.1 6.9 4 2 3 7 7 7 0 Zinc knuckle CoA_binding PF02629.14 OAJ24013.1 - 0.16 12.4 1.9 0.16 12.4 0.8 1.4 1 1 0 1 1 1 0 CoA binding domain DUF3446 PF11928.3 OAJ24013.1 - 0.49 10.6 5.0 1 9.6 3.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3446) Tuberculin PF12198.3 OAJ24014.1 - 0.07 13.0 3.8 0.11 12.3 2.7 1.3 1 0 0 1 1 1 0 Theoretical tuberculin protein NUC153 PF08159.7 OAJ24015.1 - 9.1e-08 31.5 0.0 9.1e-08 31.5 0.0 3.0 3 0 0 3 3 3 1 NUC153 domain BUD22 PF09073.5 OAJ24015.1 - 0.0056 15.8 25.4 0.0056 15.8 17.6 4.0 4 0 0 4 4 4 1 BUD22 TMEM51 PF15345.1 OAJ24015.1 - 0.023 14.3 0.8 0.023 14.3 0.5 2.8 3 1 0 3 3 3 0 Transmembrane protein 51 Ank_5 PF13857.1 OAJ24016.1 - 1.8e-30 104.2 0.3 1.5e-09 37.7 0.0 5.0 2 1 3 5 5 4 4 Ankyrin repeats (many copies) Ank PF00023.25 OAJ24016.1 - 4e-30 102.0 0.0 9.9e-07 28.2 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 OAJ24016.1 - 1.6e-29 102.0 0.0 2e-21 76.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ24016.1 - 5.1e-27 93.7 0.5 1.9e-12 47.3 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ24016.1 - 1.3e-19 68.3 0.1 0.00085 19.3 0.0 5.3 4 0 0 4 4 4 4 Ankyrin repeat FYVE PF01363.16 OAJ24016.1 - 3.4e-18 65.2 9.7 3.4e-18 65.2 6.7 2.7 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 OAJ24016.1 - 1.5e-10 40.6 3.0 1.5e-10 40.6 2.1 3.3 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ24016.1 - 0.00044 20.2 4.4 0.00044 20.2 3.1 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 OAJ24016.1 - 0.0024 17.9 1.6 0.0095 16.0 1.1 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 OAJ24016.1 - 0.042 13.5 1.7 0.16 11.6 1.2 2.0 1 0 0 1 1 1 0 RING-type zinc-finger FYVE_2 PF02318.11 OAJ24016.1 - 0.2 11.5 7.9 0.051 13.4 1.9 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger CMS1 PF14617.1 OAJ24016.1 - 0.31 10.0 0.2 2.2 7.2 0.0 2.2 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit HypA PF01155.14 OAJ24016.1 - 3.5 7.3 5.5 1 9.0 0.7 2.3 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Exo70 PF03081.10 OAJ24018.1 - 4.9e-52 176.9 0.0 5.1e-50 170.3 0.0 2.2 2 0 0 2 2 2 2 Exo70 exocyst complex subunit Vps52 PF04129.7 OAJ24018.1 - 0.011 14.2 0.1 0.12 10.8 0.0 2.4 3 0 0 3 3 3 0 Vps52 / Sac2 family Baculo_PEP_C PF04513.7 OAJ24018.1 - 0.038 13.8 0.2 0.97 9.2 0.0 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PaREP1 PF05942.6 OAJ24018.1 - 0.085 12.7 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family DUF2951 PF11166.3 OAJ24018.1 - 0.11 12.3 0.1 0.34 10.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Atrophin-1 PF03154.10 OAJ24019.1 - 3.1 5.8 6.3 3.9 5.4 4.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family Cauli_VI PF01693.11 OAJ24020.1 - 1.5e-12 47.2 0.3 2.4e-12 46.6 0.2 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Helicase_C PF00271.26 OAJ24021.1 - 1.6e-14 53.4 0.0 3.5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 OAJ24021.1 - 1.9e-05 24.3 0.1 5.7e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Dicer dimerisation domain TPR_10 PF13374.1 OAJ24022.1 - 0.028 14.3 0.5 0.028 14.3 0.4 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat RNase_H PF00075.19 OAJ24023.1 - 1.5e-25 90.0 0.0 2e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 OAJ24023.1 - 2.7e-17 62.5 0.1 4.8e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin PROL5-SMR PF15621.1 OAJ24024.1 - 1.4 9.3 9.9 2.2 8.7 6.9 1.3 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family SUI1 PF01253.17 OAJ24025.1 - 1.3e-31 108.1 1.1 1.7e-31 107.8 0.8 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Ribonuclease_3 PF00636.21 OAJ24026.1 - 0.015 15.7 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease III domain Fe_hyd_lg_C PF02906.9 OAJ24027.1 - 5.5e-57 193.1 0.1 5.5e-56 189.9 0.0 2.4 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SR-25 PF10500.4 OAJ24027.1 - 6 6.2 11.3 5.8 6.3 4.2 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein HSP70 PF00012.15 OAJ24030.1 - 9.9e-156 519.1 0.1 1.3e-155 518.7 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAJ24030.1 - 2e-08 33.2 0.1 1.3e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Not1 PF04054.10 OAJ24032.1 - 6.4e-106 354.4 0.0 1.9e-105 352.8 0.0 1.9 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 OAJ24032.1 - 5e-54 181.9 3.6 1.1e-53 180.9 2.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) TPM PF04536.9 OAJ24032.1 - 0.1 12.4 0.1 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase YppF PF14178.1 OAJ24032.1 - 0.14 11.6 0.4 1.2 8.7 0.1 2.6 3 0 0 3 3 3 0 YppF-like protein Usp PF00582.21 OAJ24033.1 - 5.6e-19 68.7 6.2 2.8e-18 66.4 0.0 3.6 3 1 1 4 4 4 2 Universal stress protein family DER1 PF04511.10 OAJ24037.1 - 3.6e-47 160.4 1.4 4.1e-47 160.2 1.0 1.0 1 0 0 1 1 1 1 Der1-like family RhoGAP PF00620.22 OAJ24038.1 - 2e-38 131.4 0.0 4.6e-38 130.2 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 OAJ24038.1 - 4.3e-16 59.1 0.0 1.1e-14 54.5 0.0 2.9 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 OAJ24038.1 - 4.3e-09 36.3 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif PH_9 PF15410.1 OAJ24038.1 - 0.00046 20.3 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 OAJ24038.1 - 0.015 15.4 0.0 0.49 10.6 0.0 2.4 2 0 0 2 2 2 0 PH domain R3H PF01424.17 OAJ24039.1 - 1.5e-10 40.5 0.5 2.7e-10 39.7 0.4 1.4 1 0 0 1 1 1 1 R3H domain SLY PF12485.3 OAJ24039.1 - 0.017 15.3 2.0 5.1 7.3 0.3 2.5 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein DUF1180 PF06679.7 OAJ24039.1 - 0.66 9.8 9.4 0.48 10.2 3.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TPR_11 PF13414.1 OAJ24040.1 - 9.1e-07 28.4 3.5 0.0017 17.9 0.0 2.9 3 0 0 3 3 3 2 TPR repeat SHNi-TPR PF10516.4 OAJ24040.1 - 0.00017 20.7 2.5 0.00022 20.3 0.1 2.2 2 0 0 2 2 2 1 SHNi-TPR TPR_2 PF07719.12 OAJ24040.1 - 0.00027 20.6 7.3 0.31 11.0 0.9 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ24040.1 - 0.00069 19.5 3.0 0.068 13.1 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ24040.1 - 0.059 13.0 4.1 5.3 6.8 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ24040.1 - 0.091 12.6 1.3 2.9 7.9 0.0 3.7 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ24040.1 - 0.33 10.8 8.9 1.5 8.7 0.9 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF177 PF02620.12 OAJ24040.1 - 0.79 9.7 4.2 0.25 11.3 0.5 1.9 2 0 0 2 2 2 0 Uncharacterized ACR, COG1399 TPR_14 PF13428.1 OAJ24040.1 - 0.92 10.3 10.5 0.96 10.2 0.5 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Nucleoplasmin PF03066.10 OAJ24040.1 - 1.1 8.8 8.0 2.3 7.7 5.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin PilJ PF13675.1 OAJ24040.1 - 1.1 9.5 5.8 2.8 8.2 0.1 3.6 3 2 1 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term TPR_16 PF13432.1 OAJ24040.1 - 2 9.1 17.6 0.099 13.3 0.6 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat NOA36 PF06524.7 OAJ24040.1 - 3.4 6.8 8.5 5.8 6.0 5.9 1.3 1 0 0 1 1 1 0 NOA36 protein Tubulin PF00091.20 OAJ24041.1 - 9.4e-73 244.5 0.0 1.7e-72 243.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 OAJ24041.1 - 3.7e-41 140.1 0.0 6.6e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 OAJ24041.1 - 0.00027 20.9 0.0 0.00066 19.7 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 OAJ24041.1 - 0.023 14.1 0.0 0.052 13.0 0.0 1.6 2 0 0 2 2 2 0 Tubulin domain zf-C3HC4_3 PF13920.1 OAJ24042.1 - 0.00046 19.7 3.1 0.00083 18.9 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ24042.1 - 0.0015 18.3 7.0 0.0026 17.5 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 OAJ24042.1 - 0.0023 17.5 5.2 0.004 16.7 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ24042.1 - 0.014 15.4 6.6 0.026 14.5 4.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BTV_NS2 PF04514.7 OAJ24042.1 - 0.54 9.0 5.2 0.95 8.2 3.6 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 C2 PF00168.25 OAJ24043.1 - 3.3e-21 74.9 0.0 2.3e-14 53.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain Flagellin_IN PF07196.8 OAJ24043.1 - 0.069 13.1 0.5 0.37 10.8 0.0 2.3 2 0 0 2 2 2 0 Flagellin hook IN motif WD40 PF00400.27 OAJ24046.1 - 1.9e-50 166.9 27.3 5.4e-11 41.9 0.8 10.9 11 0 0 11 11 11 9 WD domain, G-beta repeat Nucleoporin_N PF08801.6 OAJ24046.1 - 0.054 12.2 0.2 20 3.7 0.1 3.0 2 1 0 3 3 3 0 Nup133 N terminal like tRNA-synt_2b PF00587.20 OAJ24047.1 - 5.4e-30 104.2 0.0 1e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ24047.1 - 1.4e-05 24.9 0.0 3.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Transposase_21 PF02992.9 OAJ24048.1 - 0.00063 18.8 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Kinesin PF00225.18 OAJ24050.1 - 1e-109 366.3 0.0 1.6e-109 365.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 OAJ24050.1 - 1.2e-30 105.9 0.0 2.9e-30 104.7 0.0 1.7 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 OAJ24050.1 - 1.5e-15 57.2 0.0 5e-15 55.5 0.0 1.9 1 0 0 1 1 1 1 PH domain KIF1B PF12423.3 OAJ24050.1 - 5.6e-11 42.3 0.1 1.5e-10 40.9 0.1 1.8 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 OAJ24050.1 - 1.5e-06 28.2 0.0 7.1e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 FHA domain PH_11 PF15413.1 OAJ24050.1 - 0.00033 20.8 0.4 0.0014 18.9 0.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain RVT_1 PF00078.22 OAJ24051.1 - 1e-14 54.4 0.0 1.9e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ24051.1 - 1.5e-08 34.7 0.0 4e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ24051.1 - 0.011 16.1 0.0 0.028 14.9 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.15 OAJ24051.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease gag_pre-integrs PF13976.1 OAJ24052.1 - 8.3e-06 25.3 0.0 2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain RVP PF00077.15 OAJ24052.1 - 0.0059 16.4 0.0 0.0091 15.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_2 PF07727.9 OAJ24053.1 - 2.2e-75 252.7 0.0 2.9e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 OAJ24053.1 - 0.0054 16.4 0.0 0.026 14.3 0.0 2.2 3 0 0 3 3 3 1 Reverse transcriptase-like Cys_Met_Meta_PP PF01053.15 OAJ24054.1 - 2.5e-59 200.5 0.0 2.8e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme WD40 PF00400.27 OAJ24055.1 - 1.6e-44 148.2 12.2 2.5e-10 39.8 0.0 7.2 7 1 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 OAJ24055.1 - 0.00083 18.8 0.1 0.0092 15.4 0.0 2.5 2 1 1 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.11 OAJ24055.1 - 0.0034 15.7 0.0 1.1 7.4 0.0 2.6 2 1 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 OAJ24055.1 - 0.064 11.3 0.9 1.7 6.6 0.6 2.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 FA_desaturase PF00487.19 OAJ24056.1 - 1.2e-08 34.7 15.7 2e-08 33.9 10.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase LETM1 PF07766.8 OAJ24059.1 - 1.9e-95 318.9 1.6 1.9e-95 318.9 1.1 2.2 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.1 OAJ24059.1 - 0.00015 21.8 0.4 0.0017 18.4 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.1 OAJ24059.1 - 0.0028 17.2 0.2 0.011 15.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 OAJ24059.1 - 0.015 14.5 2.2 1.9 8.0 0.0 3.4 4 0 0 4 4 4 0 EF hand EF-hand_6 PF13405.1 OAJ24059.1 - 0.059 13.2 3.3 7.6 6.7 0.0 4.0 4 0 0 4 4 4 0 EF-hand domain Rot1 PF10681.4 OAJ24060.1 - 4.7e-61 205.8 1.8 5.8e-61 205.5 1.3 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal NAD_synthase PF02540.12 OAJ24061.1 - 1.9e-23 82.6 0.0 2.2e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 NAD synthase CN_hydrolase PF00795.17 OAJ24061.1 - 1.8e-12 46.9 0.0 3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.16 OAJ24061.1 - 0.11 11.9 0.0 0.29 10.5 0.0 1.6 1 1 0 1 1 1 0 Asparagine synthase CcmD PF04995.9 OAJ24063.1 - 0.11 12.2 0.5 0.22 11.2 0.3 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) LETM1 PF07766.8 OAJ24065.1 - 2.7e-17 62.6 0.1 1.1e-08 34.4 0.0 2.4 2 1 0 2 2 2 2 LETM1-like protein RAP1 PF07218.6 OAJ24065.1 - 2.1 6.3 6.6 4.1 5.3 4.6 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) adh_short_C2 PF13561.1 OAJ24066.1 - 7e-24 84.9 0.0 1.5e-23 83.8 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 OAJ24066.1 - 7.4e-23 81.3 1.0 1.7e-22 80.1 0.7 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 OAJ24066.1 - 4.7e-16 58.6 0.8 1.3e-15 57.2 0.5 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 OAJ24066.1 - 5.7e-14 51.9 0.0 1.3e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.20 OAJ24066.1 - 1.1e-11 44.9 0.5 8.6e-08 32.2 0.0 2.7 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 OAJ24066.1 - 1.2e-05 25.1 0.6 0.00069 19.3 0.0 2.6 2 0 0 2 2 2 1 KR domain Thiolase_N PF00108.18 OAJ24066.1 - 0.002 17.1 0.1 0.0044 16.0 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain RNA_pol_Rpc34 PF05158.7 OAJ24067.1 - 3.7e-74 249.8 1.4 2.1e-63 214.5 0.2 2.3 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit HTH_36 PF13730.1 OAJ24067.1 - 0.031 14.4 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_45 PF14947.1 OAJ24067.1 - 0.068 12.9 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix MRC1 PF09444.5 OAJ24068.1 - 3.5e-17 63.0 20.7 3.5e-17 63.0 14.3 5.4 5 1 0 5 5 5 1 MRC1-like domain GP38 PF05268.6 OAJ24068.1 - 0.66 9.3 10.9 1.1 8.6 7.5 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 DUF4254 PF14063.1 OAJ24069.1 - 0.085 12.4 1.1 0.18 11.4 0.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4254) DUF904 PF06005.7 OAJ24069.1 - 0.29 11.4 4.2 0.39 11.0 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF465 PF04325.8 OAJ24069.1 - 0.44 10.2 5.1 1.7 8.4 3.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF465) CTP_transf_1 PF01148.15 OAJ24070.1 - 0.0004 20.1 3.4 0.0004 20.1 2.3 4.4 3 2 1 5 5 5 2 Cytidylyltransferase family DDE_Tnp_4 PF13359.1 OAJ24071.1 - 4.9e-26 91.2 0.0 6.2e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ24071.1 - 6.8e-11 41.9 0.0 2.7e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 Plant transposon protein DDE_Tnp_1 PF01609.16 OAJ24071.1 - 8e-08 32.0 0.1 0.0093 15.5 0.0 2.2 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.1 OAJ24071.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.2 OAJ24072.1 - 5.6e-14 52.5 1.6 5.6e-14 52.5 1.1 2.5 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ24072.1 - 8.3e-07 29.0 0.8 2.4e-06 27.5 0.6 1.9 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 OAJ24072.1 - 0.029 14.2 0.1 0.13 12.1 0.1 2.1 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ24072.1 - 0.042 13.9 0.2 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain GST_N_3 PF13417.1 OAJ24073.1 - 2e-07 31.1 0.0 3.9e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAJ24073.1 - 7.5e-07 28.9 3.1 1.1e-06 28.3 2.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ24073.1 - 3.4e-06 27.4 0.0 5.9e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAJ24073.1 - 0.00019 21.3 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ24073.1 - 0.0065 16.4 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_L35p PF01632.14 OAJ24074.1 - 4.2e-11 42.5 1.0 7e-11 41.8 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L35 HsbA PF12296.3 OAJ24075.1 - 4.5e-12 45.9 4.5 6.2e-12 45.4 3.1 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A CheZ PF04344.8 OAJ24075.1 - 0.0036 16.9 0.1 0.0047 16.6 0.1 1.1 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ FimP PF09766.4 OAJ24076.1 - 4e-23 82.0 11.6 5e-23 81.7 8.0 1.1 1 0 0 1 1 1 1 Fms-interacting protein Mating_N PF12731.2 OAJ24076.1 - 0.082 12.7 0.4 0.18 11.7 0.3 1.6 1 0 0 1 1 1 0 Mating-type protein beta 1 DUF1376 PF07120.6 OAJ24076.1 - 0.21 11.7 3.6 1.6 8.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1376) HAUS-augmin3 PF14932.1 OAJ24076.1 - 1.6 7.8 13.2 4.9 6.2 9.1 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 V_ATPase_I PF01496.14 OAJ24076.1 - 2.1 6.0 6.7 12 3.6 4.6 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 OAJ24076.1 - 4.6 6.8 17.4 6.1 6.3 0.6 2.2 1 1 1 2 2 2 0 IncA protein HsbA PF12296.3 OAJ24078.1 - 2.1e-12 46.9 1.9 2.9e-12 46.5 1.3 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A WPP PF13943.1 OAJ24078.1 - 0.17 12.0 0.8 0.23 11.6 0.0 1.6 2 0 0 2 2 2 0 WPP domain PIF1 PF05970.9 OAJ24079.1 - 7.8e-52 176.4 0.0 1.4e-51 175.5 0.0 1.4 1 1 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ24079.1 - 3.7e-31 108.2 0.0 9.1e-31 107.0 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 OAJ24079.1 - 3.3e-07 30.1 0.0 1e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 OAJ24079.1 - 0.002 17.7 0.0 0.02 14.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain T2SE PF00437.15 OAJ24079.1 - 0.0034 16.3 0.6 0.0077 15.1 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 OAJ24079.1 - 0.004 16.8 0.0 0.0086 15.7 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase DUF2075 PF09848.4 OAJ24079.1 - 0.01 14.8 0.0 0.071 12.0 0.0 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 OAJ24079.1 - 0.011 15.3 0.4 1.9 7.9 0.1 3.0 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 OAJ24079.1 - 0.025 14.3 0.1 0.085 12.6 0.1 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 OAJ24079.1 - 0.038 14.1 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 OAJ24079.1 - 0.059 13.0 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.1 OAJ24079.1 - 0.12 12.5 0.0 0.42 10.7 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ResIII PF04851.10 OAJ24079.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Herpes_Helicase PF02689.9 OAJ24079.1 - 0.47 8.1 0.0 3.1 5.4 0.0 2.0 2 0 0 2 2 2 0 Helicase Dimer_Tnp_hAT PF05699.9 OAJ24082.1 - 4.6e-08 32.5 0.0 1e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RRM_1 PF00076.17 OAJ24083.1 - 2.2e-20 72.0 0.0 5.5e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ24083.1 - 5.1e-16 58.4 0.1 1.9e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ24083.1 - 5.8e-10 38.8 0.0 1.8e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 OAJ24083.1 - 1.9e-09 37.6 21.5 7.3e-08 32.6 14.9 2.5 1 1 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal AAA_12 PF13087.1 OAJ24086.1 - 6.5e-32 110.5 0.0 1.1e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAJ24086.1 - 4.1e-29 101.8 0.0 2.8e-28 99.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ24086.1 - 2.2e-09 36.9 0.5 7.3e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 OAJ24086.1 - 3.1e-08 33.4 0.1 0.0009 18.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 OAJ24086.1 - 0.00026 20.0 0.0 0.0014 17.6 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 OAJ24086.1 - 0.0076 15.5 0.0 0.57 9.4 0.0 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 OAJ24086.1 - 0.025 14.3 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.1 OAJ24086.1 - 0.033 14.3 0.0 0.12 12.5 0.0 2.0 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD_C PF13361.1 OAJ24086.1 - 0.069 12.5 0.0 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 OAJ24086.1 - 0.13 12.3 1.1 0.81 9.8 0.0 2.8 3 1 0 3 3 3 0 AAA domain Pro_CA PF00484.14 OAJ24088.1 - 2.2e-35 121.9 0.1 3.9e-35 121.1 0.1 1.4 1 0 0 1 1 1 1 Carbonic anhydrase SWM_repeat PF13753.1 OAJ24088.1 - 0.0061 15.6 0.1 0.012 14.6 0.1 1.4 1 0 0 1 1 1 1 Putative flagellar system-associated repeat Phospholip_A2_2 PF05826.7 OAJ24088.1 - 0.08 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Phospholipase A2 zf-RING_2 PF13639.1 OAJ24089.1 - 0.011 15.5 0.0 0.011 15.5 0.0 2.0 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.1 OAJ24089.1 - 0.18 11.5 1.1 38 4.0 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF745 PF05335.8 OAJ24089.1 - 0.55 9.7 8.7 0.072 12.6 1.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF745) ADH_N PF08240.7 OAJ24091.1 - 9.8e-29 99.3 2.1 2.6e-28 97.9 1.4 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ24091.1 - 3.5e-22 78.3 0.2 5.8e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PQQ PF01011.16 OAJ24091.1 - 0.0024 17.3 0.1 0.0053 16.2 0.0 1.6 1 0 0 1 1 1 1 PQQ enzyme repeat RVT_3 PF13456.1 OAJ24092.1 - 0.021 14.5 0.1 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like DNA_pol_viral_C PF00336.13 OAJ24092.1 - 0.1 11.8 0.1 0.33 10.1 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain Helicase_C PF00271.26 OAJ24095.1 - 1.5e-06 28.0 0.0 3.3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ24095.1 - 4.2e-05 23.1 0.0 9.2e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C2H2 PF00096.21 OAJ24095.1 - 0.01 16.1 2.7 0.01 16.1 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ24095.1 - 0.22 11.9 10.3 0.54 10.7 1.8 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ24095.1 - 2.8 8.4 11.2 7.2 7.1 3.6 3.7 2 1 0 2 2 2 0 Zinc-finger double domain Thi4 PF01946.12 OAJ24097.1 - 1.1e-47 162.0 0.0 1.6e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Thi4 family TPR_11 PF13414.1 OAJ24098.1 - 2.3e-15 55.9 8.7 9.8e-05 21.9 0.3 7.1 6 0 0 6 6 6 3 TPR repeat TPR_2 PF07719.12 OAJ24098.1 - 5.1e-11 41.6 18.2 0.2 11.6 0.0 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ24098.1 - 1.8e-10 41.1 27.9 0.0016 19.0 0.0 7.7 8 1 0 8 8 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ24098.1 - 2.8e-10 40.0 24.1 2.6e-05 24.0 1.4 7.4 5 2 3 8 8 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ24098.1 - 1.3e-08 34.1 9.6 0.29 10.8 0.3 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ24098.1 - 1.6e-08 34.3 28.3 0.27 11.9 0.5 11.3 8 2 3 11 11 11 3 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ24098.1 - 5.1e-07 29.0 3.7 0.42 10.5 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ24098.1 - 1.1e-06 28.8 12.0 3.1e-05 24.2 0.8 6.2 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ24098.1 - 7.7e-06 25.3 10.4 5.6 7.0 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ24098.1 - 8.1e-06 25.9 16.0 0.47 11.0 0.2 9.5 10 0 0 10 10 9 1 Tetratricopeptide repeat BTAD PF03704.12 OAJ24098.1 - 5.3e-05 23.5 8.3 0.049 13.9 0.2 3.6 2 1 0 2 2 2 2 Bacterial transcriptional activator domain TPR_9 PF13371.1 OAJ24098.1 - 0.00028 20.6 14.2 0.23 11.3 1.0 6.3 3 2 3 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ24098.1 - 0.00034 20.6 13.9 0.0021 18.1 0.6 5.3 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 OAJ24098.1 - 0.00072 19.4 10.1 0.48 10.4 0.3 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ24098.1 - 0.0024 17.9 0.9 6.7 7.1 0.0 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat PPR_3 PF13812.1 OAJ24098.1 - 0.026 14.7 0.1 0.94 9.9 0.0 3.5 2 0 0 2 2 2 0 Pentatricopeptide repeat domain ChAPs PF09295.5 OAJ24098.1 - 0.25 10.0 0.0 0.59 8.8 0.0 1.5 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.9 OAJ24098.1 - 0.53 10.8 13.4 0.93 10.1 0.1 6.0 6 0 0 6 6 3 0 Tetratricopeptide repeat DUF2404 PF10296.4 OAJ24099.1 - 0.027 14.5 0.0 0.075 13.1 0.0 1.7 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) FAM176 PF14851.1 OAJ24099.1 - 4.9 6.8 7.8 8.1 6.1 0.2 2.3 2 0 0 2 2 2 0 FAM176 family Barwin PF00967.12 OAJ24104.1 - 0.015 14.9 0.1 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Barwin family DPBB_1 PF03330.13 OAJ24104.1 - 0.028 14.4 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel GN3L_Grn1 PF08701.6 OAJ24109.1 - 9.3e-24 83.1 18.5 9.3e-24 83.1 12.9 2.4 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MRP-S25 PF13741.1 OAJ24110.1 - 1.6e-45 155.3 0.0 1.2e-44 152.5 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 OAJ24110.1 - 9.7e-05 22.2 2.1 0.017 15.0 0.0 2.4 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S23 SR-25 PF10500.4 OAJ24110.1 - 4.3 6.7 11.2 7.6 5.9 7.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cullin_binding PF03556.10 OAJ24114.1 - 4.8e-31 107.3 0.0 8.2e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 OAJ24114.1 - 1.6e-07 30.7 0.1 2.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Herpes_UL21 PF03252.8 OAJ24114.1 - 0.051 12.0 1.0 0.055 11.9 0.2 1.3 2 0 0 2 2 2 0 Herpesvirus UL21 Abhydrolase_6 PF12697.2 OAJ24116.1 - 1.9e-13 50.8 0.2 1e-12 48.4 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ24116.1 - 0.00041 20.1 0.0 0.0069 16.1 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family zf-CCHC PF00098.18 OAJ24117.1 - 3e-32 108.9 46.9 2.6e-07 30.2 0.6 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ24117.1 - 1.2e-07 31.2 37.5 0.017 14.8 0.1 6.1 6 0 0 6 6 6 4 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ24117.1 - 7.6e-07 28.7 33.3 0.0074 15.9 0.2 6.0 3 2 3 6 6 6 4 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ24117.1 - 6.4e-06 25.5 35.8 0.0066 15.9 0.9 6.1 4 2 2 6 6 6 5 Zinc knuckle Mu-like_Com PF10122.4 OAJ24117.1 - 0.087 11.8 0.2 0.087 11.8 0.2 4.3 3 2 2 5 5 5 0 Mu-like prophage protein Com DZR PF12773.2 OAJ24117.1 - 7.2 6.5 35.9 6.8 6.6 2.2 4.4 2 1 0 2 2 2 0 Double zinc ribbon DnaJ_CXXCXGXG PF00684.14 OAJ24117.1 - 9 6.4 39.5 0.71 9.9 7.8 4.5 3 2 0 3 3 3 0 DnaJ central domain zf-H2C2_2 PF13465.1 OAJ24118.1 - 1.6e-05 24.9 10.1 0.00035 20.7 1.1 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ24118.1 - 0.00036 20.6 8.9 0.066 13.5 0.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type GTP_EFTU PF00009.22 OAJ24119.1 - 2.2e-47 160.9 0.0 4e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 OAJ24119.1 - 9.6e-22 76.6 0.3 4.3e-10 39.3 0.0 2.7 2 0 0 2 2 2 2 Elongation Factor G, domain II EFG_C PF00679.19 OAJ24119.1 - 6.8e-17 61.1 0.3 2.5e-14 52.9 0.2 2.5 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 OAJ24119.1 - 1.9e-07 31.0 0.0 7.9e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 OAJ24119.1 - 0.069 12.7 0.0 0.32 10.5 0.0 2.0 2 0 0 2 2 2 0 Elongation factor G, domain IV OGG_N PF07934.7 OAJ24120.1 - 8.8e-22 77.2 0.0 5e-21 74.8 0.0 2.1 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain NmrA PF05368.8 OAJ24120.1 - 5.3e-11 42.2 0.0 0.00043 19.6 0.0 3.3 3 0 0 3 3 3 3 NmrA-like family HhH-GPD PF00730.20 OAJ24120.1 - 6e-10 39.3 0.0 1.3e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 OAJ24120.1 - 0.0007 19.1 0.0 0.0022 17.5 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif NAD_binding_10 PF13460.1 OAJ24120.1 - 0.0048 16.9 0.1 0.055 13.4 0.0 2.6 2 1 0 2 2 2 1 NADH(P)-binding DUF2416 PF10315.4 OAJ24121.1 - 1.9e-09 37.6 2.4 8.8e-09 35.5 1.7 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) HSP90 PF00183.13 OAJ24127.1 - 6e-85 285.6 18.5 7.9e-85 285.2 12.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 OAJ24127.1 - 1.1e-11 44.3 0.0 2.2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAJ24127.1 - 1.6e-11 44.0 0.1 1.6e-11 44.0 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF45 PF01863.12 OAJ24127.1 - 0.49 10.1 5.9 0.94 9.2 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 CDC45 PF02724.9 OAJ24127.1 - 1.7 6.6 8.8 2.3 6.1 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 OAJ24127.1 - 2 8.2 11.7 2.9 7.7 8.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.11 OAJ24127.1 - 2.2 7.6 11.6 4.3 6.6 8.0 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 YIF1 PF03878.10 OAJ24128.1 - 2.7e-72 242.7 0.0 3.7e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 YIF1 Ribosomal_L11_N PF03946.9 OAJ24128.1 - 0.54 9.7 8.8 0.029 13.8 2.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain Yip1 PF04893.12 OAJ24128.1 - 0.71 9.3 17.5 0.041 13.3 6.0 2.3 1 1 0 2 2 2 0 Yip1 domain SUV3_C PF12513.3 OAJ24129.1 - 5.8e-15 54.4 0.2 1.2e-14 53.4 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 OAJ24129.1 - 9.1e-11 41.4 0.0 1.9e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RNase_PH PF01138.16 OAJ24130.1 - 1.3e-33 116.1 0.1 1.8e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 OAJ24130.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 MCM PF00493.18 OAJ24131.1 - 2e-133 444.3 0.0 3.1e-133 443.6 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 OAJ24131.1 - 1.6e-22 80.2 0.0 9.3e-22 77.7 0.0 2.3 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 OAJ24131.1 - 3.8e-08 33.1 0.0 1e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 OAJ24131.1 - 3.9e-07 29.4 0.0 0.00016 20.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 OAJ24131.1 - 0.00014 21.5 0.0 0.0024 17.4 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAJ24131.1 - 0.0076 15.7 0.0 0.7 9.3 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_32 PF13654.1 OAJ24131.1 - 0.12 11.0 0.2 0.24 10.0 0.2 1.4 1 0 0 1 1 1 0 AAA domain Ldh_1_N PF00056.18 OAJ24132.1 - 0.0019 18.0 0.1 0.0028 17.5 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain PIF1 PF05970.9 OAJ24133.1 - 3.9e-47 160.9 0.0 6.8e-47 160.1 0.0 1.4 1 1 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ24133.1 - 3.1e-30 105.2 0.0 1.7e-29 102.8 0.0 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 OAJ24133.1 - 0.00036 20.1 0.0 0.0011 18.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ24133.1 - 0.0014 18.2 0.1 0.0052 16.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 OAJ24133.1 - 0.056 13.1 0.1 0.17 11.5 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 OAJ24133.1 - 0.061 13.5 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ24133.1 - 0.12 12.5 0.0 0.45 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 OAJ24133.1 - 0.59 9.6 4.7 1.6 8.1 0.2 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Med12 PF09497.5 OAJ24134.1 - 2.4e-23 81.8 0.0 6.1e-23 80.5 0.0 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 HMG_CoA_synt_N PF01154.12 OAJ24135.1 - 8.9e-83 276.0 0.3 1.6e-82 275.2 0.1 1.5 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 OAJ24135.1 - 2.1e-82 276.7 0.0 2.7e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal Ribosomal_L1 PF00687.16 OAJ24135.1 - 0.026 13.8 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family Med14 PF08638.6 OAJ24136.1 - 3.9e-37 127.3 0.0 7.4e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 ARPC4 PF05856.7 OAJ24137.1 - 2.6e-76 254.7 3.5 2.8e-76 254.6 2.4 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) CBP4 PF07960.6 OAJ24138.1 - 1e-13 51.0 0.0 1.2e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.1 OAJ24138.1 - 0.00018 21.2 0.0 0.0002 21.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4574) DUF4414 PF14377.1 OAJ24138.1 - 0.088 12.7 0.2 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) DUF1206 PF06724.6 OAJ24138.1 - 0.11 12.2 0.5 0.22 11.2 0.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) CsbD PF05532.7 OAJ24139.1 - 7.7e-06 25.4 20.6 0.0032 17.1 4.7 2.9 1 1 1 2 2 2 2 CsbD-like DUF1804 PF08822.6 OAJ24141.1 - 0.07 12.8 0.0 0.33 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) DUF3025 PF11227.3 OAJ24141.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) RAP1 PF07218.6 OAJ24142.1 - 3.6 5.5 4.1 4.8 5.1 2.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NAP PF00956.13 OAJ24143.1 - 4.4e-85 284.6 5.9 4.4e-85 284.6 4.1 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Kelch_4 PF13418.1 OAJ24144.1 - 1.1e-24 85.8 1.8 6.5e-08 32.2 0.0 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 OAJ24144.1 - 7e-21 73.8 6.7 8.4e-05 22.6 0.1 7.0 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.1 OAJ24144.1 - 1.8e-13 50.0 0.0 0.00062 19.8 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 OAJ24144.1 - 4.3e-13 48.5 0.0 1.5e-06 27.6 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 OAJ24144.1 - 8e-13 48.0 0.0 0.0071 16.2 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 OAJ24144.1 - 4.6e-05 23.0 1.0 0.2 11.5 0.0 3.9 4 0 0 4 4 4 2 Kelch motif PQQ_3 PF13570.1 OAJ24144.1 - 0.014 15.6 0.0 0.09 13.0 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain G-alpha PF00503.15 OAJ24145.1 - 4.2e-110 368.0 0.1 5.1e-110 367.8 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 OAJ24145.1 - 2.1e-12 46.6 0.2 2e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 OAJ24145.1 - 0.0005 20.5 0.0 0.89 10.0 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 OAJ24145.1 - 0.011 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 OAJ24145.1 - 0.012 15.1 0.1 0.032 13.6 0.0 1.7 1 1 1 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 OAJ24145.1 - 0.013 15.4 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 OAJ24145.1 - 0.037 13.1 0.2 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region CPT PF07931.7 OAJ24145.1 - 0.057 13.0 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Rad1 PF02144.11 OAJ24146.1 - 8.1e-67 224.8 0.0 1.1e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 OAJ24146.1 - 0.11 11.5 0.1 9.4 5.2 0.0 2.2 1 1 1 2 2 2 0 Rad9 DUF2834 PF11196.3 OAJ24147.1 - 0.034 14.2 3.4 0.89 9.7 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2834) GHMP_kinases_N PF00288.21 OAJ24148.1 - 7e-08 32.4 1.2 2.6e-07 30.5 0.8 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain DNA_pol_B_thumb PF14791.1 OAJ24151.1 - 2.6e-20 71.8 0.0 6.9e-20 70.5 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 OAJ24151.1 - 7.9e-20 70.9 0.1 6.3e-19 68.0 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase beta palm HHH_8 PF14716.1 OAJ24151.1 - 4.4e-07 29.9 0.1 1.2e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 OAJ24151.1 - 5.7e-07 28.9 0.0 1.8e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 OAJ24151.1 - 1.5e-05 25.0 0.1 0.00065 19.8 0.0 2.9 3 0 0 3 3 3 1 Helix-hairpin-helix domain XPG_I PF00867.13 OAJ24152.1 - 1.1e-26 92.6 0.0 2.4e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 OAJ24152.1 - 3.3e-25 88.2 0.0 8e-25 87.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 OAJ24152.1 - 0.00059 19.3 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 OAJ24152.1 - 0.042 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Hemerythrin PF01814.18 OAJ24153.1 - 1.3e-08 35.1 9.6 1.4e-07 31.7 5.7 1.8 2 1 1 3 3 3 2 Hemerythrin HHE cation binding domain DDE_Tnp_IS1595 PF12762.2 OAJ24153.1 - 0.06 13.1 0.5 0.18 11.6 0.3 1.7 2 0 0 2 2 2 0 ISXO2-like transposase domain DUF2031 PF09592.5 OAJ24153.1 - 0.22 10.6 3.5 0.12 11.5 0.8 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2031) NAD_binding_2 PF03446.10 OAJ24154.1 - 4.4e-23 81.9 0.1 6.7e-23 81.3 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 OAJ24154.1 - 1.8e-08 34.5 0.0 3.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.1 OAJ24154.1 - 2.3e-08 34.1 0.1 5.1e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 OAJ24154.1 - 2.2e-05 24.7 0.1 0.00033 21.0 0.0 2.5 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Acyl_transf_3 PF01757.17 OAJ24155.1 - 2.3e-09 36.5 25.9 4.1e-09 35.7 17.9 1.5 1 1 0 1 1 1 1 Acyltransferase family JmjC PF02373.17 OAJ24156.1 - 1.4e-12 47.8 0.0 3.5e-12 46.5 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 OAJ24156.1 - 3.9e-10 39.6 0.0 2.9e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Cupin-like domain F-box-like PF12937.2 OAJ24156.1 - 0.00076 19.1 0.0 0.0023 17.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like Cupin_4 PF08007.7 OAJ24156.1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein CTP_synth_N PF06418.9 OAJ24157.1 - 5.8e-116 386.4 0.0 7.9e-116 385.9 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 OAJ24157.1 - 6.9e-47 159.3 0.0 1.1e-36 126.0 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase class-I CbiA PF01656.18 OAJ24157.1 - 0.0031 16.9 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Acetate_kinase PF00871.12 OAJ24158.1 - 4.3e-07 28.8 0.0 0.0021 16.6 0.0 2.1 2 0 0 2 2 2 2 Acetokinase family Acetate_kinase PF00871.12 OAJ24160.1 - 2.6e-58 197.4 0.0 1.2e-43 149.1 0.0 2.1 2 0 0 2 2 2 2 Acetokinase family AAA PF00004.24 OAJ24163.1 - 2.1e-32 112.0 0.0 4.3e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAJ24163.1 - 0.00015 21.5 0.1 0.0019 17.9 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 OAJ24163.1 - 0.00029 20.8 0.1 0.00029 20.8 0.0 3.0 3 2 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 OAJ24163.1 - 0.0019 18.3 0.1 0.027 14.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 OAJ24163.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAJ24163.1 - 0.0062 15.9 0.5 0.11 11.9 0.1 2.5 1 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ24163.1 - 0.013 15.2 1.8 0.065 12.9 0.0 2.9 3 0 0 3 3 3 0 Part of AAA domain AAA_17 PF13207.1 OAJ24163.1 - 0.022 15.5 0.1 0.43 11.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.9 OAJ24163.1 - 0.029 14.2 0.0 0.077 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zot PF05707.7 OAJ24163.1 - 0.033 13.6 0.0 0.41 10.0 0.0 2.4 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_24 PF13479.1 OAJ24163.1 - 0.068 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain OrfB_Zn_ribbon PF07282.6 OAJ24163.1 - 0.11 12.2 0.4 0.5 10.0 0.1 2.2 3 0 0 3 3 3 0 Putative transposase DNA-binding domain CN_hydrolase PF00795.17 OAJ24164.1 - 2.1e-30 105.4 0.0 3e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RRM_1 PF00076.17 OAJ24165.1 - 2.7e-29 100.5 0.1 7.6e-18 63.9 0.2 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ24165.1 - 1.4e-20 73.0 0.1 1.8e-12 47.0 0.1 3.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ24165.1 - 1.8e-12 46.8 0.0 2.8e-07 30.2 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 OAJ24165.1 - 2.6e-10 39.7 0.1 0.0006 19.4 0.0 2.8 2 0 0 2 2 2 2 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 OAJ24165.1 - 0.017 14.8 0.4 9.7 6.0 0.1 2.9 3 0 0 3 3 3 0 Limkain b1 Nup35_RRM PF05172.8 OAJ24165.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Peptidase_S55 PF05580.7 OAJ24165.1 - 0.15 11.4 0.0 0.64 9.4 0.0 2.0 2 0 0 2 2 2 0 SpoIVB peptidase S55 Ndc80_HEC PF03801.8 OAJ24167.1 - 6e-37 126.5 0.0 7.5e-37 126.2 0.0 1.1 1 0 0 1 1 1 1 HEC/Ndc80p family LSM PF01423.17 OAJ24168.1 - 3.4e-16 58.5 0.9 4.3e-16 58.2 0.7 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 OAJ24168.1 - 0.034 14.0 0.1 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_C PF02237.12 OAJ24168.1 - 0.099 12.3 0.9 0.18 11.5 0.7 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain SRP9-21 PF05486.7 OAJ24169.1 - 8e-17 60.7 0.5 1e-16 60.4 0.3 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) AAA_27 PF13514.1 OAJ24169.1 - 0.0077 13.9 1.2 0.0089 13.7 0.8 1.0 1 0 0 1 1 1 1 AAA domain Exo_endo_phos PF03372.18 OAJ24170.1 - 2.3e-28 99.8 0.1 4.4e-28 98.8 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF605 PF04652.11 OAJ24170.1 - 5.3 6.3 20.4 9.5 5.4 14.2 1.3 1 0 0 1 1 1 0 Vta1 like TMPIT PF07851.8 OAJ24172.1 - 1.2 8.1 2.8 3.4 6.6 1.9 1.7 1 0 0 1 1 1 0 TMPIT-like protein UBX PF00789.15 OAJ24173.1 - 3.3e-10 39.8 0.0 5.2e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 UBX domain HIT PF01230.18 OAJ24174.1 - 2.1e-23 82.6 0.0 2.7e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 OAJ24174.1 - 2.9e-07 30.7 0.0 4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Glycos_transf_3 PF00591.16 OAJ24175.1 - 7e-68 228.7 0.0 1.2e-63 214.9 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 OAJ24175.1 - 0.00013 21.5 0.3 0.00031 20.2 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Acyl-CoA_dh_M PF02770.14 OAJ24175.1 - 0.089 12.3 0.2 0.26 10.8 0.1 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain Methyltransf_23 PF13489.1 OAJ24176.1 - 9.6e-11 41.6 0.0 2.3e-10 40.4 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ24176.1 - 1e-08 35.7 0.0 1.7e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ24176.1 - 1.6e-07 31.6 0.0 4.3e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ24176.1 - 1.1e-06 28.9 0.0 6e-06 26.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ24176.1 - 7.1e-06 25.6 0.0 9.4e-05 22.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ24176.1 - 2.2e-05 24.7 0.0 4.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAJ24176.1 - 0.00012 21.2 0.0 0.00031 19.8 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 OAJ24176.1 - 0.00027 20.9 0.1 0.00095 19.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ24176.1 - 0.036 13.4 0.0 0.4 10.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain MetW PF07021.7 OAJ24176.1 - 0.057 12.8 0.2 0.13 11.6 0.0 1.6 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 OAJ24176.1 - 0.065 12.3 0.0 0.18 10.8 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 OAJ24176.1 - 0.099 12.1 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 OAJ24176.1 - 0.15 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB MFS_1 PF07690.11 OAJ24180.1 - 3.6e-22 78.5 45.6 3.1e-12 45.8 20.5 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Rep_fac-A_3 PF08661.6 OAJ24181.1 - 1.9e-27 95.3 0.3 2.1e-27 95.1 0.2 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DEAD PF00270.24 OAJ24183.1 - 1.6e-16 60.2 0.0 2.6e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ24183.1 - 3.6e-05 23.5 0.0 0.00019 21.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RFX_DNA_binding PF02257.10 OAJ24184.1 - 1.4e-16 60.4 0.0 2.4e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain POT1 PF02765.12 OAJ24185.1 - 5.2e-11 42.6 0.0 1.2e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Cyto_heme_lyase PF01265.12 OAJ24186.1 - 9.4e-72 241.7 0.2 2.1e-71 240.5 0.1 1.5 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase PX PF00787.19 OAJ24187.1 - 8.2e-22 77.1 0.6 2e-21 75.9 0.4 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 OAJ24187.1 - 1.1e-07 31.4 1.4 0.024 13.8 0.1 3.5 3 0 0 3 3 3 2 Vps5 C terminal like BAR PF03114.13 OAJ24187.1 - 0.00038 20.0 0.8 0.64 9.4 0.0 3.1 3 0 0 3 3 3 2 BAR domain APC2 PF08672.6 OAJ24187.1 - 0.016 15.4 0.1 1.6 9.0 0.0 2.9 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 Dynamitin PF04912.9 OAJ24187.1 - 0.061 12.1 0.2 0.12 11.1 0.2 1.4 1 0 0 1 1 1 0 Dynamitin SUA5 PF03481.8 OAJ24191.1 - 0.071 13.1 0.1 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative GTP-binding controlling metal-binding GST_C_4 PF14834.1 OAJ24191.1 - 0.078 12.9 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pox_VLTF3 PF04947.9 OAJ24191.1 - 0.087 12.3 0.0 0.094 12.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like RVT_1 PF00078.22 OAJ24192.1 - 7.2e-12 45.1 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MethyTransf_Reg PF10119.4 OAJ24192.1 - 0.046 14.2 0.0 0.28 11.7 0.0 2.1 2 0 0 2 2 2 0 Predicted methyltransferase regulatory domain Preseq_ALAS PF09029.5 OAJ24193.1 - 0.0061 16.5 0.1 0.025 14.5 0.0 2.0 2 0 0 2 2 2 1 5-aminolevulinate synthase presequence DUF4218 PF13960.1 OAJ24193.1 - 0.19 11.1 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Homeobox PF00046.24 OAJ24194.1 - 7.5e-19 67.0 1.5 1.1e-18 66.5 1.1 1.3 1 0 0 1 1 1 1 Homeobox domain DRIM PF07539.7 OAJ24195.1 - 1.9e-43 147.2 0.0 6.5e-43 145.5 0.0 2.1 1 0 0 1 1 1 1 Down-regulated in metastasis ParcG PF10274.4 OAJ24195.1 - 0.034 14.0 0.5 0.73 9.7 0.0 2.7 2 0 0 2 2 2 0 Parkin co-regulated protein Sec7_N PF12783.2 OAJ24195.1 - 0.12 11.8 4.1 0.35 10.2 0.0 3.6 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal G-alpha PF00503.15 OAJ24196.1 - 9.9e-125 416.2 0.1 1.2e-124 416.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 OAJ24196.1 - 1e-14 54.1 0.1 6.1e-09 35.3 0.0 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ24196.1 - 4.5e-05 22.6 0.1 0.047 12.8 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 OAJ24196.1 - 8e-05 23.1 0.1 0.077 13.4 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 OAJ24196.1 - 0.04 13.4 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain UvdE PF03851.9 OAJ24197.1 - 4.7e-91 304.6 0.0 6.7e-91 304.1 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE PGA2 PF07543.7 OAJ24197.1 - 5.7 6.7 19.9 0.57 9.9 5.1 2.6 2 0 0 2 2 2 0 Protein trafficking PGA2 Plasmodium_Vir PF05795.6 OAJ24197.1 - 8.7 5.4 6.5 19 4.3 4.5 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CRISPR_Cse1 PF09481.5 OAJ24198.1 - 0.024 13.4 0.5 0.13 10.9 0.1 1.9 2 0 0 2 2 2 0 CRISPR-associated protein Cse1 (CRISPR_cse1) PAP2 PF01569.16 OAJ24202.1 - 4.1e-10 39.4 7.0 1.5e-09 37.5 4.9 1.9 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 OAJ24202.1 - 8.3e-05 22.1 8.4 0.00042 19.8 5.8 2.1 1 1 0 1 1 1 1 PAP2 superfamily Serglycin PF04360.7 OAJ24202.1 - 0.011 15.4 5.3 0.011 15.4 3.7 4.5 2 1 1 3 3 3 0 Serglycin PAP2_C PF14360.1 OAJ24202.1 - 2.1 8.6 8.3 0.42 10.9 2.5 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Ribosomal_L37ae PF01780.14 OAJ24203.1 - 2.7e-39 132.9 7.0 3e-39 132.7 4.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 OAJ24203.1 - 0.0015 18.3 2.3 0.0023 17.6 1.6 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 OAJ24203.1 - 0.0075 16.0 4.8 1.1 9.0 3.3 2.4 1 1 0 1 1 1 1 BED zinc finger Zn-ribbon_8 PF09723.5 OAJ24203.1 - 0.033 14.1 1.8 0.27 11.2 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain A2L_zn_ribbon PF08792.5 OAJ24203.1 - 0.05 13.0 4.5 0.22 11.0 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-FCS PF06467.9 OAJ24203.1 - 0.08 12.6 2.5 0.14 11.8 0.2 2.0 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.1 OAJ24203.1 - 0.14 12.4 7.4 0.31 11.4 0.7 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Elf1 PF05129.8 OAJ24203.1 - 0.16 11.6 3.5 0.28 10.9 2.5 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like C1_1 PF00130.17 OAJ24203.1 - 0.19 11.5 2.5 0.27 10.9 1.7 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Tnp_zf-ribbon_2 PF13842.1 OAJ24203.1 - 0.24 11.8 3.1 0.46 10.9 2.1 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon OrfB_Zn_ribbon PF07282.6 OAJ24203.1 - 0.25 11.0 4.5 0.29 10.8 2.4 1.6 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Sgf11 PF08209.6 OAJ24203.1 - 0.41 9.9 2.2 1.1 8.5 0.0 2.4 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Ribosomal_L44 PF00935.14 OAJ24203.1 - 2.3 8.2 7.5 7.4 6.6 1.5 2.2 1 1 1 2 2 2 0 Ribosomal protein L44 Sec8_exocyst PF04048.9 OAJ24204.1 - 1.6e-33 115.3 0.2 4.2e-33 113.9 0.1 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 OAJ24204.1 - 1.2e-05 24.4 0.4 2.6e-05 23.2 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 OAJ24204.1 - 1.4e-05 24.9 0.6 0.00014 21.7 0.1 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2451 PF10474.4 OAJ24204.1 - 0.03 14.0 0.0 0.099 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) COG6 PF06419.6 OAJ24205.1 - 0.21 9.6 0.2 0.28 9.2 0.1 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 HAD PF12710.2 OAJ24206.1 - 6.6e-17 62.3 0.0 2.4e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 OAJ24206.1 - 1.6e-16 60.0 0.1 1.1e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 OAJ24206.1 - 2.3e-13 51.0 5.1 3.2e-09 37.5 3.3 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ24206.1 - 8.4e-13 48.0 0.0 2.2e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAJ24206.1 - 0.0022 17.5 0.1 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase eIF2A PF08662.6 OAJ24207.1 - 1.6e-81 272.6 0.1 4.7e-79 264.6 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 OAJ24207.1 - 0.0089 15.8 3.6 0.58 10.1 0.1 4.3 6 0 0 6 6 6 1 WD domain, G-beta repeat CDV3 PF15359.1 OAJ24207.1 - 0.013 15.5 2.2 0.013 15.5 1.5 3.7 2 1 1 4 4 4 0 Carnitine deficiency-associated protein 3 Proteasome_A_N PF10584.4 OAJ24207.1 - 2.1 7.7 4.4 31 3.9 0.0 3.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature EBP PF05241.7 OAJ24208.1 - 1.1e-05 24.5 5.7 2.1e-05 23.6 3.9 1.4 1 1 0 1 1 1 1 Emopamil binding protein Pkinase PF00069.20 OAJ24209.1 - 7.9e-58 195.6 0.0 9.3e-58 195.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ24209.1 - 3.3e-20 72.2 0.0 4.6e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ24209.1 - 2.4e-07 30.7 0.4 1.7e-05 24.6 0.2 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAJ24209.1 - 0.0084 15.7 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 OAJ24209.1 - 0.02 13.9 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ24209.1 - 0.09 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HTH_28 PF13518.1 OAJ24210.1 - 0.00068 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 OAJ24210.1 - 0.015 15.1 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Transposase HTH_23 PF13384.1 OAJ24210.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Nup54 PF13874.1 OAJ24211.1 - 4e-21 75.1 4.5 4.3e-19 68.5 0.0 2.9 3 0 0 3 3 3 2 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 OAJ24211.1 - 1e-06 28.9 43.6 1e-06 28.9 30.2 4.0 2 2 1 3 3 3 2 Nucleoporin FG repeat region DUF1748 PF08520.5 OAJ24212.1 - 7.8e-21 73.4 0.0 9.1e-21 73.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) MmgE_PrpD PF03972.9 OAJ24213.1 - 1.2e-147 491.6 0.6 2e-147 490.9 0.4 1.3 1 0 0 1 1 1 1 MmgE/PrpD family DUF1162 PF06650.7 OAJ24215.1 - 9e-75 251.4 0.1 8.9e-71 238.3 0.0 4.0 3 1 1 4 4 4 3 Protein of unknown function (DUF1162) Chorein_N PF12624.2 OAJ24215.1 - 2.8e-40 136.5 0.4 1e-39 134.7 0.0 2.2 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 OAJ24215.1 - 3.7e-08 33.4 0.2 2.5e-07 30.7 0.0 2.5 2 0 0 2 2 2 1 ATG C terminal domain Serinc PF03348.10 OAJ24216.1 - 0.0031 16.3 0.1 0.0038 16.0 0.1 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) RNB PF00773.14 OAJ24218.1 - 3.3e-89 299.3 0.0 4.4e-89 298.9 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 OAJ24218.1 - 3.1e-07 30.5 0.0 1e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 PIN domain DicB PF05358.6 OAJ24218.1 - 0.12 11.8 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 DicB protein Apolipoprotein PF01442.13 OAJ24225.1 - 0.039 13.4 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 OAJ24225.1 - 0.076 13.4 0.5 0.12 12.8 0.4 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF2316 PF10078.4 OAJ24225.1 - 0.15 12.1 0.1 0.33 10.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Helitron_like_N PF14214.1 OAJ24226.1 - 8.6e-09 35.3 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Cellulase PF00150.13 OAJ24229.1 - 0.00039 19.7 0.0 0.00053 19.2 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4604 PF15377.1 OAJ24231.1 - 2.1e-16 60.5 26.4 4.1e-16 59.5 18.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) Med19 PF10278.4 OAJ24231.1 - 9.5 5.8 18.3 1.8 8.2 0.8 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 ATP-synt_ab PF00006.20 OAJ24232.1 - 3e-62 209.9 0.0 4.1e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 OAJ24232.1 - 1.5e-16 60.9 0.0 3e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 OAJ24232.1 - 1.5e-11 44.3 0.3 2.7e-11 43.5 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 OAJ24232.1 - 0.002 18.0 0.1 0.004 17.0 0.1 1.5 1 0 0 1 1 1 1 HAS barrel domain DUF561 PF04481.7 OAJ24232.1 - 0.046 12.6 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) zf-FCS PF06467.9 OAJ24234.1 - 0.007 15.9 3.4 0.012 15.1 2.3 1.4 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif TnpB_IS66 PF05717.8 OAJ24234.1 - 0.16 11.4 0.0 0.81 9.1 0.0 2.1 2 0 0 2 2 2 0 IS66 Orf2 like protein DUF581 PF04570.9 OAJ24234.1 - 0.25 10.6 2.1 0.59 9.4 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF581) EF_assoc_2 PF08356.7 OAJ24235.1 - 0.00031 20.4 0.0 0.00051 19.7 0.0 1.3 1 0 0 1 1 1 1 EF hand associated MAP65_ASE1 PF03999.7 OAJ24235.1 - 7 5.1 8.4 8 4.9 5.8 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) p450 PF00067.17 OAJ24238.1 - 2e-65 221.1 0.0 6.7e-50 169.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF1864 PF08933.6 OAJ24238.1 - 0.088 11.3 0.0 0.15 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) FAD_binding_2 PF00890.19 OAJ24239.1 - 1e-08 34.4 0.0 1.7e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain His_Phos_2 PF00328.17 OAJ24240.1 - 1.9e-29 103.1 0.0 2.3e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Aminotran_MocR PF12897.2 OAJ24240.1 - 0.041 12.4 0.0 0.061 11.8 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase DDE_Tnp_4 PF13359.1 OAJ24241.1 - 2.4e-24 85.7 0.0 4.2e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease YrbL-PhoP_reg PF10707.4 OAJ24241.1 - 4.8e-05 22.7 0.0 0.00011 21.5 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pinin_SDK_memA PF04696.8 OAJ24242.1 - 0.021 14.4 16.1 0.063 12.8 11.1 1.9 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region CsbD PF05532.7 OAJ24243.1 - 8.8e-19 66.9 16.6 6e-10 38.6 3.4 2.0 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.7 OAJ24243.1 - 0.00085 19.3 1.6 0.0016 18.4 0.7 1.8 1 1 0 1 1 1 1 Heat shock protein 9/12 UCH PF00443.24 OAJ24244.1 - 3.4e-61 206.7 0.0 4.5e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ24244.1 - 1.1e-35 123.5 3.0 1.1e-26 93.9 0.1 2.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 OAJ24244.1 - 0.00064 19.0 0.6 0.08 12.2 0.8 2.3 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Baculo_ME53 PF06061.6 OAJ24244.1 - 0.0071 15.3 1.5 0.01 14.8 1.1 1.1 1 0 0 1 1 1 1 Baculoviridae ME53 adh_short PF00106.20 OAJ24245.1 - 4.4e-07 29.9 0.1 9.1e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ24245.1 - 4.6e-06 26.5 0.0 7.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 OAJ24245.1 - 0.0002 21.0 0.3 0.00031 20.4 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 OAJ24245.1 - 0.00076 19.8 1.2 0.0045 17.3 0.5 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 OAJ24245.1 - 0.0042 16.7 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 KR domain ApbA PF02558.11 OAJ24245.1 - 0.089 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DEAD PF00270.24 OAJ24246.1 - 7.5e-49 165.4 0.0 4.1e-47 159.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ24246.1 - 5.8e-27 93.3 0.0 2.5e-26 91.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 OAJ24246.1 - 3.1e-05 22.9 0.0 4.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 OAJ24246.1 - 3.2e-05 23.8 0.0 0.00021 21.1 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 OAJ24246.1 - 0.00085 19.3 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 OAJ24246.1 - 0.11 10.8 0.0 0.71 8.2 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1253) Glyco_hydro_65m PF03632.10 OAJ24247.1 - 4.6e-76 255.8 2.8 1.6e-75 254.1 0.5 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 OAJ24247.1 - 1.3e-23 83.6 0.0 2.1e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 OAJ24247.1 - 0.0058 16.6 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain DUF2152 PF10222.4 OAJ24247.1 - 0.36 8.9 0.0 24 2.9 0.0 2.7 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2152) PRKCSH PF07915.8 OAJ24251.1 - 4.5e-12 46.5 0.0 1.1e-07 32.5 0.0 2.8 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein TPR_12 PF13424.1 OAJ24253.1 - 0.094 12.6 0.1 0.27 11.1 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TRIC PF05197.8 OAJ24254.1 - 0.0016 17.8 0.1 0.0054 16.1 0.0 1.8 1 1 0 1 1 1 1 TRIC channel UPF0126 PF03458.8 OAJ24254.1 - 0.0055 16.2 6.9 0.1 12.2 0.6 3.1 3 1 0 3 3 3 2 UPF0126 domain ETC_C1_NDUFA4 PF04800.7 OAJ24255.1 - 2.8e-31 107.3 0.1 3.6e-31 107.0 0.1 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region Proteasome PF00227.21 OAJ24256.1 - 6e-47 159.3 0.0 7.8e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAJ24256.1 - 4.5e-14 51.4 0.1 7.8e-14 50.6 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SLAC1 PF03595.12 OAJ24257.1 - 7.2e-65 218.7 46.7 1e-64 218.3 32.4 1.2 1 0 0 1 1 1 1 Voltage-dependent anion channel adh_short PF00106.20 OAJ24258.1 - 9.4e-14 51.6 0.5 6.6e-12 45.6 0.4 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ24258.1 - 4.9e-06 26.3 0.0 1.6e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAJ24258.1 - 0.034 14.1 0.1 0.09 12.7 0.1 1.7 1 1 1 2 2 2 0 NADH(P)-binding Shikimate_DH PF01488.15 OAJ24258.1 - 0.11 12.6 0.1 0.29 11.2 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 OAJ24258.1 - 0.2 11.4 2.2 0.16 11.7 0.2 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Complex1_49kDa PF00346.14 OAJ24261.1 - 5.7e-127 422.3 0.0 7.8e-127 421.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 OAJ24261.1 - 0.17 10.6 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase MAS20 PF02064.10 OAJ24262.1 - 6.7e-17 61.5 0.5 1.5e-15 57.1 0.4 2.2 1 1 0 1 1 1 1 MAS20 protein import receptor Thioredoxin PF00085.15 OAJ24263.1 - 1e-25 89.3 0.0 1.8e-21 75.7 0.0 2.9 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.1 OAJ24263.1 - 5.3e-07 29.8 0.5 5.6e-06 26.5 0.2 2.6 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 OAJ24263.1 - 0.00013 21.8 0.1 0.0028 17.6 0.1 2.7 2 2 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.1 OAJ24263.1 - 0.0026 17.8 0.2 0.024 14.7 0.1 2.5 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 OAJ24263.1 - 0.0042 16.7 0.0 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA family COPIIcoated_ERV PF07970.7 OAJ24264.1 - 2.3e-61 207.2 4.9 5.9e-33 114.3 0.3 2.7 2 1 0 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 OAJ24264.1 - 3.6e-31 106.9 0.2 1e-30 105.5 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PNPOx_C PF10590.4 OAJ24265.1 - 6e-20 70.4 3.4 1.1e-19 69.6 2.3 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 OAJ24265.1 - 7.5e-17 61.1 0.1 8.5e-16 57.7 0.0 2.2 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RNase_H2_suC PF08615.6 OAJ24266.1 - 4.8e-13 49.1 25.2 1.2e-12 47.8 1.9 5.3 3 2 0 3 3 3 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Acyl_transf_3 PF01757.17 OAJ24271.1 - 3.4e-06 26.1 27.2 5.9e-06 25.3 18.8 1.3 1 0 0 1 1 1 1 Acyltransferase family Glyco_tranf_2_3 PF13641.1 OAJ24274.1 - 6.1e-28 98.1 0.0 8.2e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 OAJ24274.1 - 5.8e-17 62.0 5.0 5.8e-17 62.0 3.5 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 OAJ24274.1 - 6.2e-09 35.3 0.0 9.7e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 OAJ24274.1 - 1.4e-06 28.0 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 TPR_12 PF13424.1 OAJ24280.1 - 0.018 14.9 0.2 0.06 13.2 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ24280.1 - 0.12 12.3 0.8 4.9 7.2 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Tyrosinase PF00264.15 OAJ24281.1 - 1.7e-38 132.9 2.1 2.4e-38 132.5 1.4 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Laminin_II PF06009.7 OAJ24283.1 - 0.012 15.3 1.3 0.024 14.3 0.2 1.8 1 1 1 2 2 2 0 Laminin Domain II DUF1465 PF07323.7 OAJ24283.1 - 0.029 13.9 3.6 0.82 9.2 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) GP41 PF00517.12 OAJ24283.1 - 0.036 13.6 0.0 0.06 12.8 0.0 1.4 1 1 0 1 1 1 0 Retroviral envelope protein GreA_GreB_N PF03449.10 OAJ24283.1 - 0.041 13.9 1.8 0.097 12.7 1.1 1.7 1 1 1 2 2 2 0 Transcription elongation factor, N-terminal Cep57_CLD PF14073.1 OAJ24283.1 - 0.08 12.7 1.2 0.096 12.5 0.8 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Seryl_tRNA_N PF02403.17 OAJ24283.1 - 0.088 12.8 3.2 0.23 11.4 2.2 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.3 OAJ24283.1 - 0.11 11.6 1.7 0.27 10.4 0.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Nup88 PF10168.4 OAJ24283.1 - 0.19 9.5 1.6 0.23 9.2 1.1 1.0 1 0 0 1 1 1 0 Nuclear pore component Dor1 PF04124.7 OAJ24283.1 - 0.37 9.1 2.9 2.1 6.7 0.2 2.0 1 1 1 2 2 2 0 Dor1-like family Tyrosinase PF00264.15 OAJ24284.1 - 1.4e-35 123.4 4.1 1.8e-35 123.0 2.8 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.15 OAJ24285.1 - 1.6e-37 129.8 0.3 2.2e-37 129.3 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.15 OAJ24287.1 - 6.3e-36 124.6 1.2 6.3e-36 124.6 0.8 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase Peptidase_S9 PF00326.16 OAJ24289.1 - 0.091 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family tRNA-synt_2c PF01411.14 OAJ24290.1 - 6.9e-210 698.0 0.0 1.1e-209 697.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 OAJ24290.1 - 9.7e-17 60.5 0.1 2.3e-16 59.3 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Pkinase PF00069.20 OAJ24291.1 - 5.8e-56 189.5 0.0 7e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ24291.1 - 3.5e-38 131.1 0.0 4.6e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ24291.1 - 4.2e-07 29.2 0.0 1.1e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAJ24291.1 - 0.016 14.9 0.0 0.13 11.9 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family cobW PF02492.14 OAJ24293.1 - 1.4e-42 145.1 4.9 2.1e-41 141.3 3.4 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 OAJ24293.1 - 6.6e-18 64.2 0.2 1.5e-12 47.0 0.0 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain CDC45 PF02724.9 OAJ24293.1 - 0.0059 14.7 1.6 0.0086 14.1 1.1 1.2 1 0 0 1 1 1 1 CDC45-like protein AAA_22 PF13401.1 OAJ24293.1 - 0.021 14.9 0.7 0.18 11.9 0.4 2.5 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 OAJ24293.1 - 0.027 13.9 0.0 0.077 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 OAJ24293.1 - 0.039 13.5 0.1 0.081 12.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 OAJ24293.1 - 0.056 13.3 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 OAJ24293.1 - 0.057 12.9 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PEPCK_ATP PF01293.15 OAJ24293.1 - 0.099 11.1 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 OAJ24293.1 - 0.11 12.0 0.2 0.26 10.8 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 OAJ24293.1 - 0.19 12.0 3.5 2.8 8.2 2.4 2.8 1 1 0 1 1 1 0 AAA domain Nop14 PF04147.7 OAJ24293.1 - 0.26 9.1 6.9 0.4 8.5 4.8 1.2 1 0 0 1 1 1 0 Nop14-like family AAA_16 PF13191.1 OAJ24293.1 - 0.93 9.4 4.3 1.9 8.4 0.2 2.8 3 1 0 3 3 3 0 AAA ATPase domain DUF2890 PF11081.3 OAJ24293.1 - 1.4 8.9 5.4 0.35 10.8 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) DUF2457 PF10446.4 OAJ24293.1 - 10 4.7 14.1 19 3.8 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cutinase PF01083.17 OAJ24294.1 - 2.4e-30 105.6 0.0 3.1e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ24294.1 - 0.00077 19.0 0.0 0.00097 18.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ24294.1 - 0.005 16.7 0.0 0.0067 16.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 OAJ24294.1 - 0.13 12.5 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain NIR_SIR PF01077.17 OAJ24296.1 - 2.2e-29 101.8 0.1 4.2e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 OAJ24296.1 - 3.4e-21 76.0 0.0 7.3e-21 74.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 OAJ24296.1 - 5e-15 55.1 0.0 3.5e-14 52.3 0.0 2.2 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.22 OAJ24296.1 - 1.2e-13 51.2 0.4 1.2e-13 51.2 0.3 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 OAJ24296.1 - 2.7e-13 49.7 5.0 8.8e-12 44.9 3.7 2.8 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.12 OAJ24296.1 - 5.9e-11 41.8 0.0 1.1e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.21 OAJ24296.1 - 8.4e-11 41.3 0.2 3.4e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 OAJ24296.1 - 5.2e-05 23.4 1.4 0.0032 17.5 0.9 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ24296.1 - 0.0013 18.5 3.5 1.2 8.8 0.0 3.4 2 1 1 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 OAJ24296.1 - 0.0018 17.2 4.8 0.077 11.8 0.2 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ24296.1 - 0.0027 16.6 0.6 1.4 7.6 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 OAJ24296.1 - 0.0086 16.0 0.5 0.043 13.8 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 OAJ24296.1 - 0.035 14.3 0.2 17 5.7 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.13 OAJ24296.1 - 0.084 12.8 4.8 1.9 8.5 0.0 3.7 4 0 0 4 4 4 0 TrkA-N domain GIDA PF01134.17 OAJ24296.1 - 0.12 11.2 0.2 5.2 5.8 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A ThiF PF00899.16 OAJ24296.1 - 0.29 10.9 2.2 1.7 8.5 0.1 2.4 2 0 0 2 2 2 0 ThiF family Retrotrans_gag PF03732.12 OAJ24297.1 - 0.00037 20.4 0.2 0.00068 19.6 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein SPX PF03105.14 OAJ24302.1 - 4.9e-10 39.6 0.0 8.6e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 SPX domain Phage_integrase PF00589.17 OAJ24302.1 - 9.6e-07 28.6 0.0 1.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family FTR1 PF03239.9 OAJ24304.1 - 0.0055 15.6 0.4 0.0066 15.4 0.2 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3262 PF11660.3 OAJ24304.1 - 0.47 10.5 3.6 0.82 9.7 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3262) UCR_TM PF02921.9 OAJ24305.1 - 1.2e-19 70.2 2.6 2.8e-19 69.0 1.8 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 OAJ24305.1 - 1.2e-16 60.0 0.1 2.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pox_Ag35 PF03286.9 OAJ24306.1 - 0.092 12.2 15.1 0.13 11.7 10.4 1.4 1 1 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_viral_N PF00242.12 OAJ24306.1 - 0.28 10.1 9.1 0.32 9.9 6.3 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 OAJ24306.1 - 0.35 9.1 13.5 0.39 8.9 9.3 1.1 1 0 0 1 1 1 0 Transmembrane protein SAPS PF04499.10 OAJ24306.1 - 0.64 8.5 4.1 0.8 8.2 2.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2217 PF10265.4 OAJ24306.1 - 0.69 8.5 11.5 0.96 8.1 8.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) RFXA_RFXANK_bdg PF15289.1 OAJ24306.1 - 3.1 8.0 12.8 1.7 8.8 7.1 1.9 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain E1-E2_ATPase PF00122.15 OAJ24308.1 - 2.7e-67 226.1 6.6 8.2e-67 224.5 0.3 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 OAJ24308.1 - 9e-23 81.8 0.0 2.3e-22 80.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAJ24308.1 - 2.9e-13 50.3 0.0 5.4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAJ24308.1 - 1.1e-12 47.1 0.0 3.1e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 OAJ24308.1 - 0.00097 18.7 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ24308.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DMA PF03474.9 OAJ24308.1 - 0.029 14.1 0.1 1.9 8.3 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif PsbI PF02532.9 OAJ24308.1 - 0.4 10.3 0.0 0.4 10.3 0.0 3.2 4 0 0 4 4 4 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Pex2_Pex12 PF04757.9 OAJ24309.1 - 3.7e-46 157.3 4.4 2e-45 155.0 3.1 1.8 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 OAJ24309.1 - 2.9e-07 30.3 0.8 4.3e-07 29.8 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ24309.1 - 2.2e-06 27.2 0.6 3.2e-06 26.6 0.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FdhE PF04216.7 OAJ24309.1 - 0.022 14.5 0.2 0.038 13.7 0.2 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-RING_2 PF13639.1 OAJ24309.1 - 0.023 14.4 0.5 0.037 13.8 0.3 1.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 OAJ24309.1 - 0.23 11.1 0.3 0.35 10.5 0.2 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAJ24309.1 - 0.47 10.3 2.5 0.77 9.6 1.7 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING EF-1_beta_acid PF10587.4 OAJ24309.1 - 8.1 6.6 6.6 31 4.8 0.4 2.4 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Kinesin PF00225.18 OAJ24310.1 - 3.7e-103 344.7 0.0 2e-102 342.3 0.0 2.2 1 1 0 1 1 1 1 Kinesin motor domain Baculo_PEP_C PF04513.7 OAJ24310.1 - 0.24 11.1 13.5 1.3 8.8 0.1 4.5 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.4 OAJ24310.1 - 1.1 9.1 7.8 3.6 7.5 0.2 3.9 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF4126 PF13548.1 OAJ24310.1 - 5.4 6.4 4.2 13 5.1 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) Syntaxin PF00804.20 OAJ24310.1 - 8.4 6.6 18.8 0.12 12.5 1.7 4.1 3 1 1 4 4 4 0 Syntaxin PWWP PF00855.12 OAJ24311.1 - 1.8e-05 24.8 0.1 3.6e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 PWWP domain SURF1 PF02104.10 OAJ24312.1 - 1.2e-43 149.4 0.0 2.1e-43 148.6 0.0 1.4 1 1 0 1 1 1 1 SURF1 family Dynamitin PF04912.9 OAJ24313.1 - 1.7e-19 69.9 1.6 2.3e-06 26.6 0.0 4.1 4 0 0 4 4 4 4 Dynamitin Pheromone PF08015.6 OAJ24313.1 - 9.4 7.1 10.0 11 6.9 0.4 3.5 4 1 0 4 4 4 0 Fungal mating-type pheromone Snf7 PF03357.16 OAJ24314.1 - 9e-44 148.8 12.3 9e-44 148.8 8.5 2.0 2 0 0 2 2 2 2 Snf7 Misat_Tub_SegII PF10644.4 OAJ24314.1 - 0.039 14.0 0.2 0.086 12.8 0.1 1.6 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain DUF3508 PF12018.3 OAJ24314.1 - 0.072 12.0 4.4 0.26 10.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) LTXXQ PF07813.7 OAJ24314.1 - 2.8 8.4 10.9 0.14 12.6 3.1 2.1 3 0 0 3 3 3 0 LTXXQ motif family protein Atg14 PF10186.4 OAJ24314.1 - 8.1 5.2 8.6 9 5.1 5.5 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NUDIX PF00293.23 OAJ24315.1 - 2.2e-20 72.6 0.0 3.2e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain PG_binding_1 PF01471.13 OAJ24315.1 - 0.035 14.0 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Putative peptidoglycan binding domain NUDIX_2 PF13869.1 OAJ24315.1 - 0.038 13.3 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase zf-RING_2 PF13639.1 OAJ24316.1 - 1.2e-13 50.6 3.8 2.6e-13 49.5 2.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAJ24316.1 - 1.8e-13 50.3 0.7 3.1e-13 49.6 0.5 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 OAJ24316.1 - 8e-07 28.6 2.5 1.6e-06 27.6 1.8 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAJ24316.1 - 9.8e-07 28.5 0.8 1.9e-06 27.6 0.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 OAJ24316.1 - 7.2e-06 25.6 2.6 1.2e-05 24.9 1.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAJ24316.1 - 1.1e-05 24.9 4.6 4.4e-05 23.0 3.4 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ24316.1 - 1.5e-05 24.9 3.3 1.5e-05 24.9 2.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAJ24316.1 - 0.00012 21.7 2.6 0.00029 20.4 1.8 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 OAJ24316.1 - 0.0053 16.6 3.0 0.0088 15.8 1.6 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 OAJ24316.1 - 0.036 14.0 0.2 0.079 12.9 0.2 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 OAJ24316.1 - 2.1 7.9 4.0 1.3 8.6 1.4 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TMEM154 PF15102.1 OAJ24317.1 - 0.0026 17.4 1.1 0.0026 17.4 0.7 1.7 2 0 0 2 2 2 1 TMEM154 protein family DUF1191 PF06697.7 OAJ24317.1 - 0.024 13.4 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 OAJ24317.1 - 0.048 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 OAJ24317.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Plasmodium_Vir PF05795.6 OAJ24317.1 - 0.2 10.8 0.4 0.31 10.1 0.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Mucin PF01456.12 OAJ24317.1 - 0.93 9.2 26.7 0.063 13.0 13.9 2.2 3 0 0 3 3 3 0 Mucin-like glycoprotein IncA PF04156.9 OAJ24317.1 - 2.3 7.7 3.8 0.45 10.0 0.2 1.6 2 0 0 2 2 2 0 IncA protein CAP_N PF01213.14 OAJ24318.1 - 3e-80 269.8 21.9 7.3e-79 265.2 15.1 3.1 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 OAJ24318.1 - 5.7e-52 175.2 3.6 7.3e-52 174.8 2.5 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 OAJ24318.1 - 0.004 16.5 0.8 0.0067 15.8 0.5 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF2360 PF10152.4 OAJ24318.1 - 0.018 15.3 0.7 0.018 15.3 0.5 2.6 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Mito_fiss_reg PF05308.6 OAJ24318.1 - 0.046 13.0 15.8 0.33 10.2 3.9 3.2 3 0 0 3 3 3 0 Mitochondrial fission regulator RdRP_1 PF00680.15 OAJ24318.1 - 0.18 9.9 0.0 0.27 9.4 0.0 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase Ribosomal_60s PF00428.14 OAJ24318.1 - 2.9 8.3 13.3 31 5.0 0.3 4.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Glycophorin_A PF01102.13 OAJ24320.1 - 0.00022 20.9 1.0 0.00022 20.9 0.7 2.1 2 1 0 2 2 2 1 Glycophorin A GRA6 PF05084.8 OAJ24320.1 - 0.004 16.7 1.8 0.0081 15.7 1.2 1.6 1 1 0 1 1 1 1 Granule antigen protein (GRA6) DUF1191 PF06697.7 OAJ24320.1 - 0.0043 15.9 0.0 0.0065 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) TMEM154 PF15102.1 OAJ24320.1 - 0.061 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.15 OAJ24320.1 - 0.11 12.1 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Pex14_N PF04695.8 OAJ24320.1 - 2.3 8.2 7.8 0.17 11.9 1.5 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1517 PF07466.6 OAJ24320.1 - 4.1 6.3 7.5 0.65 8.9 2.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) Alpha_GJ PF03229.8 OAJ24320.1 - 6.5 7.1 20.7 0.056 13.7 5.4 2.6 2 1 0 2 2 2 0 Alphavirus glycoprotein J Ribosomal_S7 PF00177.16 OAJ24321.1 - 5.5e-39 133.0 0.7 6.8e-39 132.8 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e WD40 PF00400.27 OAJ24322.1 - 1.9e-52 173.3 13.8 1.6e-08 34.0 0.0 8.5 8 1 0 8 8 8 7 WD domain, G-beta repeat LisH PF08513.6 OAJ24322.1 - 2.8e-06 26.8 0.1 6e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 OAJ24322.1 - 0.0022 16.1 2.1 0.39 8.8 0.0 3.2 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 OAJ24322.1 - 0.018 14.5 0.0 8.4 5.9 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.1 OAJ24322.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ctr PF04145.10 OAJ24323.1 - 1.2e-37 129.2 2.1 5.5e-37 127.0 1.4 1.9 1 1 0 1 1 1 1 Ctr copper transporter family dUTPase PF00692.14 OAJ24324.1 - 1e-43 147.9 0.0 1.2e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 dUTPase Chorion_2 PF03964.10 OAJ24324.1 - 0.076 13.5 2.4 0.12 12.9 1.6 1.5 1 1 0 1 1 1 0 Chorion family 2 DUF2015 PF09435.5 OAJ24328.1 - 7.8e-27 93.5 0.1 1.8e-25 89.1 0.0 2.0 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ammonium_transp PF00909.16 OAJ24329.1 - 1.1e-105 353.4 25.8 1.2e-105 353.2 17.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Sec6 PF06046.8 OAJ24330.1 - 4.6e-143 477.2 0.0 6.5e-143 476.8 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 OAJ24330.1 - 0.00058 18.7 3.5 0.0036 16.1 0.8 2.8 3 0 0 3 3 3 1 Vps53-like, N-terminal MutS_III PF05192.13 OAJ24330.1 - 0.0015 18.3 0.0 0.013 15.2 0.0 2.6 2 1 0 2 2 2 1 MutS domain III Ribosomal_60s PF00428.14 OAJ24331.1 - 2.1e-26 92.1 9.5 2.4e-26 91.9 6.6 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 OAJ24331.1 - 0.13 10.4 0.7 0.13 10.4 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3037 PF11236.3 OAJ24331.1 - 0.14 12.2 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) RNA_pol_Rpb1_5 PF04998.12 OAJ24332.1 - 2.3e-13 50.0 0.0 3.4e-13 49.4 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Nop14 PF04147.7 OAJ24332.1 - 3.5 5.4 18.2 4.5 5.0 12.6 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 OAJ24332.1 - 4 5.7 13.5 4.8 5.5 9.3 1.1 1 0 0 1 1 1 0 Daxx Family GHMP_kinases_N PF00288.21 OAJ24333.1 - 1.1e-13 51.0 0.2 5.1e-13 48.8 0.1 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 OAJ24333.1 - 0.0013 18.8 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Thioredoxin PF00085.15 OAJ24334.1 - 3e-23 81.4 0.0 1.5e-22 79.2 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 OAJ24334.1 - 6.2e-05 23.0 0.0 0.0002 21.3 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ24334.1 - 0.00026 21.1 0.1 0.00026 21.1 0.0 3.3 3 2 0 3 3 3 1 Thioredoxin-like domain AhpC-TSA PF00578.16 OAJ24334.1 - 0.004 16.8 0.2 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 OAJ24334.1 - 0.0076 16.2 0.0 0.0076 16.2 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_6 PF13848.1 OAJ24334.1 - 0.038 13.7 0.0 0.33 10.7 0.0 2.3 1 1 0 1 1 1 0 Thioredoxin-like domain Ribosomal_60s PF00428.14 OAJ24335.1 - 3.7 8.0 8.6 0.43 10.9 0.1 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Aha1_N PF09229.6 OAJ24336.1 - 6.2e-29 100.5 0.0 8.7e-29 100.0 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 OAJ24336.1 - 8e-17 61.4 0.0 1.6e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 OAJ24336.1 - 0.0003 20.9 0.1 0.00073 19.7 0.0 1.7 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Sporozoite_P67 PF05642.6 OAJ24336.1 - 0.22 9.3 8.4 0.28 8.9 5.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MSA-2c PF12238.3 OAJ24336.1 - 0.25 10.9 7.6 0.45 10.1 5.3 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Med3 PF11593.3 OAJ24336.1 - 2 7.5 9.0 2.6 7.2 6.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Herpes_capsid PF06112.6 OAJ24336.1 - 9 6.3 14.3 21 5.1 9.9 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein VHS PF00790.14 OAJ24337.1 - 2.1e-32 111.6 0.0 4.6e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 OAJ24337.1 - 2.8e-16 58.8 0.3 4.7e-16 58.0 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ24337.1 - 1.3e-14 53.2 0.1 2.2e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ24337.1 - 2.2e-11 43.0 0.2 3.6e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 OAJ24337.1 - 0.00059 19.7 0.9 0.0031 17.4 0.2 2.5 2 1 0 2 2 2 1 GAT domain Vir_act_alpha_C PF10400.4 OAJ24337.1 - 0.014 15.7 7.2 6.5 7.1 0.0 2.8 2 0 0 2 2 2 0 Virulence activator alpha C-term Med26 PF08711.6 OAJ24337.1 - 0.11 12.0 0.8 0.71 9.4 0.0 2.2 2 0 0 2 2 2 0 TFIIS helical bundle-like domain DUF775 PF05603.7 OAJ24338.1 - 2.2e-36 125.2 0.0 2.6e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF2237 PF09996.4 OAJ24339.1 - 1.3e-32 111.7 0.9 4.2e-32 110.0 0.6 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) HEAT_EZ PF13513.1 OAJ24340.1 - 9e-28 96.0 10.5 1.1e-05 25.6 0.0 10.5 10 2 2 12 12 10 5 HEAT-like repeat HEAT_2 PF13646.1 OAJ24340.1 - 4.6e-23 81.3 6.6 2.3e-05 24.5 0.0 6.7 6 2 1 7 7 7 4 HEAT repeats HEAT PF02985.17 OAJ24340.1 - 2.5e-18 64.4 8.5 0.00024 20.9 0.1 8.5 7 0 0 7 7 7 5 HEAT repeat IBN_N PF03810.14 OAJ24340.1 - 2.9e-09 36.7 2.3 7.8e-09 35.3 0.2 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.10 OAJ24340.1 - 2.5e-06 26.0 0.3 0.0072 14.6 0.0 3.8 4 0 0 4 4 4 2 CAS/CSE protein, C-terminus Ipi1_N PF12333.3 OAJ24340.1 - 3.9e-06 26.7 0.0 4.2 7.4 0.0 6.1 7 1 1 8 8 8 1 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.2 OAJ24340.1 - 5.1e-06 26.7 0.0 0.25 11.7 0.0 5.0 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 OAJ24340.1 - 1.8e-05 23.2 0.2 0.21 9.8 0.0 3.9 4 0 0 4 4 4 2 Adaptin N terminal region CLASP_N PF12348.3 OAJ24340.1 - 2.2e-05 23.9 0.0 0.52 9.6 0.0 5.1 5 1 0 5 5 5 1 CLASP N terminal Cohesin_HEAT PF12765.2 OAJ24340.1 - 4e-05 23.4 0.2 0.74 9.8 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion UME PF08064.8 OAJ24340.1 - 7.7e-05 22.6 0.0 1.6 8.7 0.0 4.7 5 1 1 6 6 6 1 UME (NUC010) domain Cnd1 PF12717.2 OAJ24340.1 - 0.00094 19.0 0.0 5.8 6.7 0.0 4.0 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 OAJ24340.1 - 0.059 13.2 8.4 25 4.8 0.1 6.9 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat IFRD PF05004.8 OAJ24340.1 - 0.072 12.1 0.4 18 4.3 0.1 3.5 3 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) PHD PF00628.24 OAJ24341.1 - 5.4e-08 32.4 6.6 1e-07 31.4 4.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 OAJ24341.1 - 0.0021 17.3 7.9 0.0033 16.6 5.4 1.3 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.10 OAJ24341.1 - 0.23 11.1 4.6 0.43 10.3 3.2 1.4 1 0 0 1 1 1 0 CW-type Zinc Finger MRP-S28 PF10213.4 OAJ24342.1 - 5.2e-26 91.2 0.0 3e-25 88.7 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit protein SR-25 PF10500.4 OAJ24342.1 - 0.19 11.1 14.7 0.32 10.4 10.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Period_C PF12114.3 OAJ24342.1 - 2.1 7.9 10.4 3.2 7.3 7.2 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region CAF-1_p150 PF11600.3 OAJ24342.1 - 5.5 6.3 6.5 9.4 5.5 4.5 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Telomere_Sde2 PF13019.1 OAJ24343.1 - 1e-37 129.3 1.0 1.7e-37 128.6 0.0 1.8 2 0 0 2 2 2 1 Telomere stability and silencing GTSE1_N PF15259.1 OAJ24343.1 - 0.0025 17.7 1.6 0.011 15.7 0.0 2.4 1 1 1 2 2 2 1 G-2 and S-phase expressed 1 DUF848 PF05852.6 OAJ24343.1 - 0.72 9.6 4.3 0.22 11.3 0.3 1.9 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF755 PF05501.6 OAJ24343.1 - 2.5 8.1 10.7 4.5 7.3 7.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF755) DUF2890 PF11081.3 OAJ24343.1 - 4.6 7.2 11.6 6 6.8 6.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) PNRC PF15365.1 OAJ24344.1 - 9.8e-06 25.4 1.0 9.8e-06 25.4 0.7 4.4 5 2 1 6 6 6 1 Proline-rich nuclear receptor coactivator TFIIF_alpha PF05793.7 OAJ24344.1 - 0.38 9.0 16.4 0.48 8.7 11.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2992 PF11208.3 OAJ24344.1 - 0.66 9.8 9.1 1.4 8.8 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF3533 PF12051.3 OAJ24344.1 - 1.4 7.5 3.6 2.1 7.0 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) PCI PF01399.22 OAJ24345.1 - 6.1e-15 55.4 1.0 1.2e-14 54.4 0.0 2.0 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 OAJ24345.1 - 3.9e-07 29.9 0.0 8.8e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 FeoC PF09012.5 OAJ24345.1 - 0.00014 21.5 0.0 0.00042 19.9 0.0 1.8 1 0 0 1 1 1 1 FeoC like transcriptional regulator TPR_16 PF13432.1 OAJ24345.1 - 0.014 16.0 0.1 0.081 13.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat FimP PF09766.4 OAJ24345.1 - 0.029 13.4 1.7 0.044 12.8 1.2 1.3 1 0 0 1 1 1 0 Fms-interacting protein DUF1090 PF06476.7 OAJ24345.1 - 0.12 12.0 0.2 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) TPR_11 PF13414.1 OAJ24345.1 - 0.23 11.1 1.9 12 5.6 0.0 3.0 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 OAJ24345.1 - 0.95 9.5 4.2 32 4.7 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Raptor_N PF14538.1 OAJ24346.1 - 2.2e-49 167.2 0.0 2.2e-49 167.2 0.0 1.8 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 OAJ24346.1 - 3.6e-08 32.9 2.7 1 9.3 0.0 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT PF02985.17 OAJ24346.1 - 0.0022 17.9 6.6 0.41 10.8 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 OAJ24346.1 - 0.037 14.5 1.4 0.99 9.9 0.0 3.7 2 1 1 3 3 3 0 HEAT-like repeat BBS2_Mid PF14783.1 OAJ24346.1 - 0.052 13.3 0.0 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.4 OAJ24346.1 - 0.11 12.1 0.1 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain TFIIA PF03153.8 OAJ24346.1 - 0.32 10.8 13.6 0.73 9.6 9.4 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Acetyltransf_1 PF00583.19 OAJ24347.1 - 7e-13 48.4 0.0 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAJ24347.1 - 1.9e-05 24.7 0.0 2.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAJ24347.1 - 9.8e-05 22.3 0.0 0.0002 21.3 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ24347.1 - 0.00046 19.8 0.0 0.00082 19.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 OAJ24347.1 - 0.0014 18.7 0.0 0.0034 17.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAJ24347.1 - 0.0025 17.6 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 OAJ24347.1 - 0.0032 17.6 0.0 0.004 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAJ24347.1 - 0.008 16.0 0.1 0.25 11.1 0.1 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 OAJ24347.1 - 0.067 13.0 0.0 0.087 12.6 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain CLASP_N PF12348.3 OAJ24348.1 - 1.2e-67 227.6 5.2 9.2e-55 185.4 0.2 3.3 3 0 0 3 3 3 3 CLASP N terminal HEAT PF02985.17 OAJ24348.1 - 1.9e-07 30.5 1.4 0.043 13.9 0.0 4.9 5 0 0 5 5 5 2 HEAT repeat Aldo_ket_red PF00248.16 OAJ24351.1 - 1.1e-43 149.1 0.0 1.3e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Amidohydro_1 PF01979.15 OAJ24351.1 - 0.058 13.0 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family GMC_oxred_N PF00732.14 OAJ24352.1 - 1.1e-47 162.6 0.1 4.4e-24 85.1 0.1 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ24352.1 - 9.7e-32 110.2 0.0 2.1e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 OAJ24352.1 - 5.6e-06 26.2 0.1 2.1e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAJ24352.1 - 1.7e-05 23.8 0.4 0.00064 18.6 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 OAJ24352.1 - 0.00014 20.9 0.0 0.0002 20.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 OAJ24352.1 - 0.00038 19.4 0.2 0.00079 18.4 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAJ24352.1 - 0.007 16.2 0.2 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ24352.1 - 0.016 14.2 0.1 0.034 13.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 OAJ24352.1 - 0.022 13.2 0.1 0.064 11.7 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 OAJ24352.1 - 0.035 13.8 0.1 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 OAJ24352.1 - 0.038 14.0 0.0 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAJ24352.1 - 0.05 12.6 0.0 0.086 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 OAJ24352.1 - 0.053 13.5 0.1 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_6 PF00970.19 OAJ24354.1 - 5e-31 106.7 0.0 8.2e-31 106.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 OAJ24354.1 - 1.8e-28 99.2 0.0 3.2e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 OAJ24354.1 - 2.3e-06 27.6 0.0 0.00016 21.6 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF1761 PF08570.5 OAJ24354.1 - 0.036 14.0 0.8 0.054 13.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) FAD_binding_9 PF08021.6 OAJ24354.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain IQ PF00612.22 OAJ24357.1 - 0.001 18.5 0.2 0.0023 17.4 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Vfa1 PF08432.5 OAJ24358.1 - 0.19 11.7 9.0 0.23 11.4 6.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Paramyxo_ncap PF00973.14 OAJ24358.1 - 0.19 10.3 5.2 0.21 10.2 3.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Rtf2 PF04641.7 OAJ24358.1 - 1.6 7.8 8.5 2.3 7.3 5.9 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger CDC27 PF09507.5 OAJ24358.1 - 2 7.5 17.2 2.5 7.2 11.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RNA_pol_Rpc82 PF05645.8 OAJ24358.1 - 2 7.9 6.1 1.6 8.2 3.5 1.3 1 1 0 1 1 1 0 RNA polymerase III subunit RPC82 DUF4220 PF13968.1 OAJ24358.1 - 3.4 6.6 4.8 4.3 6.3 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Herpes_DNAp_acc PF04929.7 OAJ24358.1 - 3.5 6.5 6.1 4.5 6.1 4.2 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF501 PF04417.7 OAJ24358.1 - 3.6 7.4 9.6 0.15 11.9 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF501) NAM-associated PF14303.1 OAJ24358.1 - 4.1 7.6 15.5 6.5 7.0 10.7 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Ycf1 PF05758.7 OAJ24358.1 - 4.4 4.9 5.3 4.4 4.8 3.7 1.0 1 0 0 1 1 1 0 Ycf1 Ank_5 PF13857.1 OAJ24360.1 - 1.7e-11 43.9 3.8 0.0022 18.1 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ24360.1 - 5.2e-10 38.5 0.3 0.0065 16.6 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 OAJ24360.1 - 5.4e-10 39.4 0.0 0.0021 18.3 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ24360.1 - 2.1e-07 31.2 0.6 0.07 13.6 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 OAJ24360.1 - 2.3e-06 27.1 10.4 0.0066 16.2 0.1 4.1 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.8 OAJ24360.1 - 0.00053 19.5 0.0 0.0018 17.8 0.0 1.8 1 1 0 1 1 1 1 KilA-N domain MitMem_reg PF13012.1 OAJ24360.1 - 0.057 13.4 0.7 0.11 12.6 0.5 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function AAA_13 PF13166.1 OAJ24360.1 - 1.4 7.2 0.2 2 6.7 0.2 1.1 1 0 0 1 1 1 0 AAA domain SET PF00856.23 OAJ24362.1 - 6.1e-24 85.1 0.4 2.8e-23 83.0 0.0 2.2 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.11 OAJ24362.1 - 6.6e-15 55.2 10.4 6.6e-15 55.2 7.2 1.8 2 0 0 2 2 2 1 Pre-SET motif CDC45 PF02724.9 OAJ24362.1 - 6.5 4.6 7.1 12 3.7 4.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Abhydrolase_6 PF12697.2 OAJ24366.1 - 1.4e-13 51.2 15.4 6.7e-09 35.9 0.9 4.1 4 0 0 4 4 4 2 Alpha/beta hydrolase family DUF1057 PF06342.7 OAJ24366.1 - 0.64 8.7 0.0 0.98 8.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) CDP-OH_P_transf PF01066.16 OAJ24368.1 - 7.6e-16 58.2 3.4 7.6e-16 58.2 2.4 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GRIM-19 PF06212.7 OAJ24369.1 - 6.6e-33 113.1 0.0 7.7e-33 112.9 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein Ail_Lom PF06316.6 OAJ24371.1 - 0.033 13.6 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein Alpha_GJ PF03229.8 OAJ24371.1 - 0.056 13.7 2.5 11 6.3 0.0 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J DDE_3 PF13358.1 OAJ24372.1 - 0.0027 17.4 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DSPc PF00782.15 OAJ24373.1 - 3e-12 46.2 0.0 4.8e-12 45.6 0.0 1.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAJ24373.1 - 0.02 14.2 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase RCC1 PF00415.13 OAJ24377.1 - 1.3e-16 60.5 12.2 0.0006 19.9 0.0 7.3 6 3 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ24377.1 - 4.1e-12 45.3 14.6 0.029 14.0 0.0 7.9 8 1 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat tRNA-synt_1b PF00579.20 OAJ24378.1 - 1.1e-67 228.2 0.0 1.3e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Adeno_PVIII PF01310.13 OAJ24378.1 - 0.0091 15.8 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 1 Adenovirus hexon associated protein, protein VIII Choline_kinase PF01633.15 OAJ24379.1 - 1.8e-33 115.8 0.0 1.6e-22 80.1 0.0 2.9 3 1 0 3 3 3 2 Choline/ethanolamine kinase APH PF01636.18 OAJ24379.1 - 0.00094 18.9 0.8 0.038 13.7 0.0 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Metallopep PF12044.3 OAJ24380.1 - 9.7e-85 284.5 0.0 1.8e-33 115.6 0.0 3.0 3 0 0 3 3 3 3 Putative peptidase family Jacalin PF01419.12 OAJ24380.1 - 0.00063 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain Peptidase_M66 PF10462.4 OAJ24380.1 - 0.0016 17.4 0.5 0.0027 16.6 0.4 1.3 1 0 0 1 1 1 1 Peptidase M66 Thymidylate_kin PF02223.12 OAJ24382.1 - 6e-44 149.6 0.0 7.5e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 OAJ24382.1 - 4.2e-06 26.8 0.0 7.2e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 OAJ24382.1 - 0.0014 17.9 0.0 0.0037 16.5 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 OAJ24382.1 - 0.0097 15.7 0.4 0.074 12.9 0.3 2.4 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 OAJ24382.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 OAJ24382.1 - 0.025 14.5 1.0 0.1 12.5 0.7 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 OAJ24382.1 - 0.065 14.0 0.1 0.16 12.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain GCV_T PF01571.16 OAJ24383.1 - 2.5e-66 223.0 0.0 3.3e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 OAJ24383.1 - 1e-24 86.3 0.0 2.1e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 OAJ24383.1 - 0.0015 18.4 0.0 0.016 15.0 0.0 2.3 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family Grp1_Fun34_YaaH PF01184.14 OAJ24384.1 - 3.4e-22 78.7 12.4 4.6e-22 78.3 8.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2306 PF10067.4 OAJ24384.1 - 0.035 14.2 10.0 0.04 14.0 1.9 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) DNA_ligase_A_M PF01068.16 OAJ24385.1 - 9.7e-09 34.8 0.0 1.1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 ATP dependent DNA ligase domain L51_S25_CI-B8 PF05047.11 OAJ24386.1 - 8.6e-11 41.4 0.0 1.1e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Lactamase_B_2 PF12706.2 OAJ24387.1 - 1e-17 64.3 0.0 4.7e-17 62.1 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 OAJ24387.1 - 1e-07 31.8 0.0 2.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 OAJ24387.1 - 1.9e-05 24.0 0.0 4.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease PDEase_II PF02112.10 OAJ24387.1 - 0.056 12.3 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II API5 PF05918.6 OAJ24387.1 - 0.11 10.9 2.8 0.15 10.5 1.9 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) EGL-1 PF11430.3 OAJ24387.1 - 0.15 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 COesterase PF00135.23 OAJ24388.1 - 5.3e-08 32.0 0.0 9.4e-08 31.2 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 OAJ24388.1 - 1.6e-07 31.2 0.1 0.0082 15.8 0.0 3.3 2 1 1 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAJ24388.1 - 4.1e-05 23.2 1.8 0.0011 18.6 0.0 3.2 3 1 1 4 4 4 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAJ24388.1 - 0.00064 19.0 0.1 0.0016 17.6 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 OAJ24388.1 - 0.073 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase FHA PF00498.21 OAJ24389.1 - 7.5e-05 22.7 0.5 0.00013 21.9 0.3 1.4 1 0 0 1 1 1 1 FHA domain SH3_1 PF00018.23 OAJ24390.1 - 3.5e-39 131.9 8.3 2.1e-16 59.0 0.2 4.5 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 OAJ24390.1 - 4.3e-38 128.6 8.5 5.8e-13 48.1 0.1 4.2 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.7 OAJ24390.1 - 9.5e-28 95.6 0.0 1.8e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.12 OAJ24390.1 - 1.2e-21 75.9 0.0 4.2e-07 29.3 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 OAJ24390.1 - 0.00012 22.1 2.2 0.23 11.6 0.1 3.6 3 0 0 3 3 3 2 Bacterial SH3 domain PfkB PF00294.19 OAJ24391.1 - 3.5e-58 197.1 0.3 4.1e-58 196.8 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 OAJ24391.1 - 0.00031 20.0 0.0 0.00075 18.7 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Asp PF00026.18 OAJ24392.1 - 2.3e-114 381.9 0.2 2.8e-114 381.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ24392.1 - 5.1e-11 42.7 0.0 1.1e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 OAJ24392.1 - 1.1e-06 28.3 0.0 3.1e-05 23.5 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 OAJ24392.1 - 4e-06 27.2 0.0 0.017 15.5 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease DUF3564 PF12087.3 OAJ24392.1 - 0.047 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) Aldo_ket_red PF00248.16 OAJ24393.1 - 7.1e-49 166.1 0.0 8.5e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RCC1 PF00415.13 OAJ24394.1 - 3.8e-48 161.4 8.0 5.6e-07 29.6 0.3 8.6 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ24394.1 - 8.2e-33 111.3 31.4 2.9e-06 26.7 0.5 8.5 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat Nup96 PF12110.3 OAJ24395.1 - 1.4e-82 277.0 0.0 2e-82 276.5 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 OAJ24395.1 - 1.3e-40 138.4 0.0 3.4e-40 137.1 0.0 1.7 1 1 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 OAJ24395.1 - 9.8e-29 99.8 246.2 5.4e-11 42.7 26.5 12.6 2 1 10 12 12 12 8 Nucleoporin FG repeat region CBFD_NFYB_HMF PF00808.18 OAJ24396.1 - 1.4e-15 57.0 0.3 2.5e-15 56.2 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAJ24396.1 - 2e-10 40.6 0.2 3.4e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF4 PF05236.9 OAJ24396.1 - 0.099 11.8 0.5 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family SGT1 PF07093.6 OAJ24398.1 - 1.7 6.9 16.2 1.7 6.9 11.2 1.1 1 0 0 1 1 1 0 SGT1 protein MSP1_C PF07462.6 OAJ24398.1 - 1.8 6.8 10.0 2.3 6.4 6.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Dicty_REP PF05086.7 OAJ24398.1 - 4.7 4.8 7.5 5.6 4.5 5.2 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nucleoplasmin PF03066.10 OAJ24398.1 - 6 6.3 23.7 0.15 11.5 9.7 2.1 2 0 0 2 2 2 0 Nucleoplasmin Kelch_3 PF13415.1 OAJ24399.1 - 6.7e-31 105.7 20.4 7.5e-10 38.7 0.1 7.4 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 OAJ24399.1 - 9e-28 95.8 15.0 1.8e-07 30.8 0.1 7.3 6 2 0 6 6 6 5 Galactose oxidase, central domain DUF4110 PF13422.1 OAJ24399.1 - 4.6e-24 84.0 0.5 4.6e-24 84.0 0.3 4.0 4 1 1 5 5 5 1 Domain of unknown function (DUF4110) Kelch_5 PF13854.1 OAJ24399.1 - 3.2e-23 81.2 6.4 3.9e-06 26.6 0.0 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 OAJ24399.1 - 1.2e-18 66.3 10.7 2e-06 27.6 0.1 6.0 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.20 OAJ24399.1 - 4.5e-13 48.5 8.2 7.6e-07 28.5 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 OAJ24399.1 - 1.5e-11 43.5 3.2 0.00024 20.7 0.0 5.6 5 1 0 5 5 5 3 Kelch motif DUF2638 PF10937.3 OAJ24404.1 - 2.6e-08 34.8 3.4 4.3e-08 34.1 2.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2638) SNARE PF05739.14 OAJ24405.1 - 2e-07 30.5 1.6 2e-07 30.5 1.1 3.6 4 0 0 4 4 4 1 SNARE domain Polysacc_deac_2 PF04748.8 OAJ24405.1 - 0.15 11.0 3.6 0.39 9.7 0.1 2.5 3 0 0 3 3 3 0 Divergent polysaccharide deacetylase Adenylsucc_synt PF00709.16 OAJ24407.1 - 5.6e-162 539.1 0.0 6.3e-162 539.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Serinc PF03348.10 OAJ24408.1 - 4.1e-144 480.4 3.7 5.4e-144 480.0 2.5 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) Pkinase PF00069.20 OAJ24409.1 - 3.4e-10 39.5 0.0 7.9e-10 38.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ24409.1 - 0.002 17.2 0.0 0.061 12.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase AAA PF00004.24 OAJ24410.1 - 0.00051 20.2 0.3 0.0036 17.5 0.1 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 OAJ24410.1 - 0.047 12.5 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein TIP49 PF06068.8 OAJ24410.1 - 0.19 10.4 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus DUF663 PF04950.7 OAJ24412.1 - 2e-80 269.9 0.4 4.7e-80 268.7 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 OAJ24412.1 - 1.1e-29 101.8 0.0 3.2e-29 100.2 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 OAJ24412.1 - 2e-06 27.3 0.0 0.00014 21.3 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 OAJ24412.1 - 5e-06 26.6 0.1 1.9e-05 24.7 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ24412.1 - 5.3e-05 23.3 0.0 0.00019 21.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 OAJ24412.1 - 0.00021 21.0 0.1 0.00055 19.6 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 OAJ24412.1 - 0.00023 20.8 0.2 0.00081 19.0 0.0 1.9 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.4 OAJ24412.1 - 0.0011 18.5 0.1 0.0037 16.7 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 OAJ24412.1 - 0.0011 19.4 0.9 0.004 17.6 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 OAJ24412.1 - 0.0018 19.1 0.0 0.0018 19.1 0.0 3.3 3 2 0 3 3 1 1 AAA domain AAA_25 PF13481.1 OAJ24412.1 - 0.0045 16.3 0.0 0.019 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 OAJ24412.1 - 0.0052 16.9 0.6 0.011 15.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 OAJ24412.1 - 0.015 15.1 2.1 0.021 14.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 OAJ24412.1 - 0.025 14.7 0.0 0.063 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 OAJ24412.1 - 0.028 14.6 1.4 0.058 13.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.18 OAJ24412.1 - 0.038 13.9 0.1 0.12 12.3 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 OAJ24412.1 - 0.062 13.2 0.0 0.16 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 OAJ24412.1 - 0.063 12.9 0.2 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 NTPase DUF258 PF03193.11 OAJ24412.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.14 OAJ24412.1 - 0.29 10.5 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain OsmC PF02566.14 OAJ24413.1 - 1.2e-18 67.1 0.0 2.1e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 OsmC-like protein Nop14 PF04147.7 OAJ24414.1 - 0.031 12.1 3.5 0.084 10.7 2.4 1.7 1 0 0 1 1 1 0 Nop14-like family BNIP3 PF06553.7 OAJ24414.1 - 6.3 6.1 10.7 0.1 11.9 1.8 2.1 2 0 0 2 2 2 0 BNIP3 DUF2782 PF11191.3 OAJ24417.1 - 0.024 14.6 1.2 0.091 12.7 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) MIP-T3 PF10243.4 OAJ24417.1 - 0.95 7.8 19.8 1.7 7.0 13.7 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 EF-hand_7 PF13499.1 OAJ24418.1 - 1.6e-06 28.1 0.0 3.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 OAJ24418.1 - 2e-06 26.7 0.3 1.9e-05 23.6 0.0 2.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 OAJ24418.1 - 3.7e-06 26.3 0.1 1.2e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 OAJ24418.1 - 0.011 15.0 0.2 0.042 13.2 0.0 2.2 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 OAJ24418.1 - 0.042 13.4 0.3 0.47 10.0 0.1 2.3 1 1 1 2 2 2 0 EF-hand domain pair DUF4211 PF13926.1 OAJ24419.1 - 0.00037 19.9 0.0 0.0008 18.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) RRM_1 PF00076.17 OAJ24420.1 - 2.1e-17 62.5 0.0 3.2e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ24420.1 - 5.3e-16 58.3 0.0 8e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ24420.1 - 3.9e-08 33.0 0.0 5.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPI2 PF06432.6 OAJ24421.1 - 2.1e-70 237.2 1.7 4.1e-62 210.0 0.0 2.1 2 0 0 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase Tic20 PF09685.5 OAJ24421.1 - 0.17 11.8 0.0 0.17 11.8 0.0 3.3 4 0 0 4 4 4 0 Tic20-like protein GCIP PF13324.1 OAJ24422.1 - 0.006 15.8 7.7 0.018 14.2 4.6 2.3 2 1 0 2 2 2 1 Grap2 and cyclin-D-interacting FAM176 PF14851.1 OAJ24422.1 - 1.4 8.5 4.5 4.8 6.8 3.1 1.9 1 0 0 1 1 1 0 FAM176 family RRN3 PF05327.6 OAJ24422.1 - 4.8 5.1 4.9 7.3 4.5 3.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_S10 PF00450.17 OAJ24423.1 - 6.7e-90 302.2 0.0 9.3e-90 301.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Herpes_gE PF02480.11 OAJ24423.1 - 0.033 12.4 0.0 0.05 11.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Sporozoite_P67 PF05642.6 OAJ24423.1 - 6 4.6 5.6 8.7 4.0 3.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Arrestin_C PF02752.17 OAJ24424.1 - 1.8e-07 31.3 0.0 6.9e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 OAJ24424.1 - 0.00072 19.3 0.1 0.44 10.3 0.0 3.1 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain NTR2 PF15458.1 OAJ24424.1 - 0.087 12.0 0.3 7.6 5.6 0.3 2.7 3 0 0 3 3 3 0 Nineteen complex-related protein 2 NDK PF00334.14 OAJ24425.1 - 1.5e-54 183.3 0.0 1.7e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 OAJ24425.1 - 0.0099 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Photosystem I reaction centre subunit IX / PsaJ Peptidase_C97 PF05903.9 OAJ24430.1 - 1.7e-38 131.7 0.0 4e-38 130.5 0.0 1.6 2 0 0 2 2 2 1 PPPDE putative peptidase domain SRR1 PF07985.7 OAJ24430.1 - 1.1e-15 57.2 0.3 5e-15 55.1 0.1 2.2 2 0 0 2 2 2 1 SRR1 Gag_spuma PF03276.9 OAJ24431.1 - 0.13 10.5 0.0 0.19 10.0 0.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein tRNA-synt_1d PF00750.14 OAJ24432.1 - 1.4e-82 277.3 1.6 1.9e-82 276.9 1.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 OAJ24432.1 - 9.6e-21 73.9 0.0 4e-20 71.9 0.0 2.2 2 0 0 2 2 2 1 DALR anticodon binding domain WAC_Acf1_DNA_bd PF10537.4 OAJ24433.1 - 6.9e-34 116.0 0.0 1.7e-33 114.8 0.0 1.7 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 OAJ24433.1 - 1.4e-10 40.8 0.0 3.4e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 OAJ24433.1 - 1.3e-05 24.9 0.3 3.3e-05 23.6 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 OAJ24433.1 - 0.027 14.4 0.1 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 OAJ24433.1 - 0.094 12.5 1.1 0.21 11.3 0.1 2.2 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 3 DUF3275 PF11679.3 OAJ24433.1 - 4.6 6.8 15.7 0.1 12.2 1.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3275) BUD22 PF09073.5 OAJ24434.1 - 0.0002 20.5 8.4 0.00022 20.4 5.8 1.2 1 0 0 1 1 1 1 BUD22 Cwf_Cwc_15 PF04889.7 OAJ24434.1 - 0.011 15.4 6.7 0.018 14.7 4.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.9 OAJ24434.1 - 0.015 14.8 3.3 0.026 14.0 2.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.7 OAJ24434.1 - 0.031 12.2 10.5 0.038 11.9 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.12 OAJ24434.1 - 0.087 12.6 1.5 0.13 12.0 1.0 1.2 1 0 0 1 1 1 0 DDHD domain FLO_LFY PF01698.11 OAJ24434.1 - 0.24 10.1 2.5 0.31 9.8 1.8 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1510 PF07423.6 OAJ24434.1 - 0.46 9.8 9.3 0.78 9.0 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 OAJ24434.1 - 0.63 8.4 13.2 0.89 7.9 9.2 1.2 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 OAJ24434.1 - 0.64 8.6 14.0 0.88 8.2 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2890 PF11081.3 OAJ24434.1 - 1.5 8.8 6.8 2.8 7.9 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) NOA36 PF06524.7 OAJ24434.1 - 5.3 6.2 11.2 8.2 5.5 7.7 1.2 1 0 0 1 1 1 0 NOA36 protein NARP1 PF12569.3 OAJ24434.1 - 6.3 5.4 7.2 9.5 4.8 5.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FAM176 PF14851.1 OAJ24434.1 - 7.1 6.2 6.5 15 5.2 4.5 1.5 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 OAJ24434.1 - 8.5 6.7 11.9 19 5.6 8.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1793 PF08760.6 OAJ24437.1 - 4.7e-66 221.8 1.1 4.7e-66 221.8 0.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 OAJ24437.1 - 0.018 14.2 0.2 0.051 12.7 0.1 1.8 1 1 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal MutL_C PF08676.6 OAJ24440.1 - 8.5e-21 74.0 0.1 3.2e-20 72.1 0.0 1.9 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 OAJ24440.1 - 2.3e-16 59.3 0.0 5.4e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 OAJ24440.1 - 1.7e-12 47.1 0.1 6.4e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 OAJ24440.1 - 1.1e-11 44.4 0.2 5.6e-11 42.1 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1014 PF06244.7 OAJ24441.1 - 5e-12 46.1 10.5 1e-09 38.6 5.7 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF1014) HSP70 PF00012.15 OAJ24442.1 - 9.1e-67 225.3 1.9 1.5e-39 135.4 0.0 2.4 3 0 0 3 3 3 2 Hsp70 protein Actin PF00022.14 OAJ24442.1 - 0.00058 18.3 0.2 0.12 10.8 0.0 2.1 1 1 1 2 2 2 2 Actin PilM_2 PF11104.3 OAJ24442.1 - 0.03 13.2 0.0 0.19 10.5 0.0 2.0 1 1 0 1 1 1 0 Type IV pilus assembly protein PilM; CENP-B_dimeris PF09026.5 OAJ24442.1 - 0.48 10.7 4.6 1.2 9.4 3.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PilX_N PF14341.1 OAJ24443.1 - 0.051 13.2 1.8 0.14 11.8 1.3 1.7 1 0 0 1 1 1 0 PilX N-terminal An_peroxidase PF03098.10 OAJ24444.1 - 2.5e-68 230.7 0.0 3.1e-66 223.8 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 OAJ24444.1 - 3.1e-15 55.6 0.0 3.7e-14 52.1 0.0 2.2 2 0 0 2 2 2 1 Cytochrome P450 Actin PF00022.14 OAJ24445.1 - 6e-117 390.3 0.0 7.4e-117 390.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 OAJ24445.1 - 0.024 13.2 0.0 0.2 10.2 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein RINGv PF12906.2 OAJ24446.1 - 2.2e-15 56.3 11.6 3.9e-15 55.6 8.0 1.4 1 0 0 1 1 1 1 RING-variant domain HemY_N PF07219.8 OAJ24446.1 - 0.029 13.9 3.1 0.6 9.6 0.2 3.0 2 0 0 2 2 2 0 HemY protein N-terminus DUF2256 PF10013.4 OAJ24446.1 - 0.038 13.7 0.2 0.038 13.7 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_2 PF13639.1 OAJ24446.1 - 0.23 11.3 10.1 0.55 10.1 7.0 1.7 1 0 0 1 1 1 0 Ring finger domain DUF2968 PF11180.3 OAJ24446.1 - 0.41 10.0 4.6 0.55 9.5 2.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) FANCL_C PF11793.3 OAJ24446.1 - 3.5 7.6 8.5 8.4 6.4 5.9 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain RHD3 PF05879.7 OAJ24451.1 - 3e-247 822.2 0.0 3.8e-247 821.9 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Miro PF08477.8 OAJ24451.1 - 1.7e-06 28.5 0.6 8.3e-06 26.3 0.1 2.2 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 OAJ24451.1 - 1e-05 25.4 0.3 0.00013 21.8 0.0 2.3 2 0 0 2 2 2 1 Dynamin family GBP PF02263.14 OAJ24451.1 - 1.3e-05 24.4 0.2 2.6e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 OAJ24451.1 - 7.2e-05 22.7 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 OAJ24451.1 - 0.0034 17.3 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ24451.1 - 0.013 15.5 0.3 1.4 8.8 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain DUF21 PF01595.15 OAJ24452.1 - 2.1e-33 115.1 2.8 2.1e-33 115.1 2.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF21 CBS PF00571.23 OAJ24452.1 - 1e-05 25.2 1.1 1.1 9.1 0.1 3.5 3 0 0 3 3 3 3 CBS domain DcpS_C PF11969.3 OAJ24453.1 - 0.064 13.4 0.2 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding MFS_1 PF07690.11 OAJ24454.1 - 4.7e-33 114.3 34.0 3.5e-31 108.2 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ24454.1 - 3.7e-12 45.5 20.6 5.6e-12 44.9 14.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 OAJ24454.1 - 2.2e-06 26.1 4.8 4.8e-06 25.0 2.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DDE_Tnp_4 PF13359.1 OAJ24455.1 - 1.2e-26 93.1 0.0 1.5e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 OAJ24455.1 - 0.0039 16.7 0.1 0.029 13.9 0.0 2.1 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.9 OAJ24455.1 - 0.01 15.1 0.0 0.056 12.8 0.0 1.8 2 0 0 2 2 2 0 Plant transposon protein BCA_ABC_TP_C PF12399.3 OAJ24455.1 - 0.015 14.9 0.3 0.13 12.0 0.0 2.3 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter DDE_Tnp_1_2 PF13586.1 OAJ24455.1 - 0.024 14.8 0.1 0.05 13.7 0.1 1.5 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.2 OAJ24456.1 - 6.7e-14 52.2 0.3 1.1e-13 51.6 0.2 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain HHH_8 PF14716.1 OAJ24456.1 - 0.0072 16.4 0.8 0.021 14.9 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain Myb_DNA-bind_4 PF13837.1 OAJ24456.1 - 0.14 12.3 3.0 0.087 12.9 0.4 2.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Sec2p PF06428.6 OAJ24457.1 - 1.4e-14 53.7 7.4 4.3e-14 52.1 5.1 1.8 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p DUF572 PF04502.8 OAJ24457.1 - 0.75 8.9 23.6 0.013 14.7 4.4 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) KAT11 PF08214.6 OAJ24458.1 - 8.1e-25 87.6 0.1 5.1e-13 48.8 0.0 4.2 3 2 0 3 3 3 2 Histone acetylation protein zf-PARP PF00645.13 OAJ24458.1 - 2.8e-18 65.9 0.0 5.7e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Transp_cyt_pur PF02133.10 OAJ24459.1 - 4.9e-19 68.2 31.4 6.6e-19 67.7 21.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Lyase_aromatic PF00221.14 OAJ24460.1 - 1.2e-126 422.9 2.5 1.6e-126 422.5 1.7 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase TBCA PF02970.11 OAJ24461.1 - 2.7e-27 94.6 5.9 2.8e-27 94.6 4.1 2.0 1 1 1 2 2 2 1 Tubulin binding cofactor A TaqI_C PF12950.2 OAJ24461.1 - 0.021 14.5 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain RdRP_4 PF02123.11 OAJ24461.1 - 0.14 10.8 1.4 0.14 10.8 1.0 1.1 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase HN PF00423.14 OAJ24461.1 - 0.15 10.3 1.6 0.16 10.1 1.1 1.0 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase Fib_alpha PF08702.5 OAJ24461.1 - 2.3 8.3 8.0 1.2 9.2 0.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Rad52_Rad22 PF04098.10 OAJ24462.1 - 2.6e-57 192.8 0.0 4.2e-57 192.1 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein PAT1 PF09770.4 OAJ24462.1 - 0.45 8.6 6.5 0.73 8.0 4.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TPR_MLP1_2 PF07926.7 OAJ24463.1 - 0.029 14.1 0.5 0.061 13.0 0.4 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Abhydrolase_4 PF08386.5 OAJ24465.1 - 4.1e-15 55.5 0.0 1.4e-14 53.8 0.0 1.9 1 1 1 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 OAJ24465.1 - 1.7e-13 50.6 0.0 4.1e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ24465.1 - 1.8e-09 37.8 0.0 5e-08 33.1 0.0 2.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ24465.1 - 2e-05 24.3 0.0 0.00029 20.6 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Dec-1 PF04624.9 OAJ24465.1 - 0.0085 15.6 2.3 1 9.0 0.3 2.3 2 0 0 2 2 2 2 Dec-1 repeat Aminotran_5 PF00266.14 OAJ24466.1 - 1.2e-32 113.0 0.0 2.3e-31 108.9 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V IPPT PF01715.12 OAJ24467.1 - 1.6e-36 125.6 0.0 4.6e-22 78.2 0.0 3.0 2 1 0 2 2 2 2 IPP transferase AAA_17 PF13207.1 OAJ24467.1 - 0.00011 22.9 0.0 0.0008 20.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAJ24467.1 - 0.0024 18.0 0.0 0.0085 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ24467.1 - 0.0037 17.5 0.1 0.05 13.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 OAJ24467.1 - 0.005 16.8 0.6 0.05 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 OAJ24467.1 - 0.014 15.0 0.0 0.042 13.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 OAJ24467.1 - 0.031 13.5 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein IPT PF01745.11 OAJ24467.1 - 0.049 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase AAA_33 PF13671.1 OAJ24467.1 - 0.059 13.2 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 OAJ24467.1 - 0.065 13.1 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAJ24467.1 - 0.067 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 OAJ24467.1 - 0.12 11.3 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Fungal_trans PF04082.13 OAJ24468.1 - 6.2e-20 71.1 0.0 3e-19 68.9 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ24468.1 - 3.6e-07 29.9 8.0 3.6e-07 29.9 5.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAP2 PF01569.16 OAJ24469.1 - 4.2e-17 62.0 5.6 1.3e-16 60.4 3.9 1.8 1 0 0 1 1 1 1 PAP2 superfamily RecT PF03837.9 OAJ24469.1 - 0.19 11.0 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 RecT family DUF202 PF02656.10 OAJ24476.1 - 6.5e-20 71.1 2.9 6.5e-20 71.1 2.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF202) DUF2157 PF09925.4 OAJ24476.1 - 0.15 11.6 3.2 1.6 8.3 0.0 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) Glyco_hydro_18 PF00704.23 OAJ24477.1 - 1.8e-89 300.5 0.1 2.2e-89 300.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LsmAD PF06741.8 OAJ24478.1 - 1.6e-24 85.7 0.9 3.3e-24 84.7 0.6 1.6 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 OAJ24478.1 - 7.2e-10 38.6 0.0 1.5e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain L31 PF09784.4 OAJ24479.1 - 9.9e-42 141.2 1.0 1.1e-41 141.0 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Na_H_Exchanger PF00999.16 OAJ24481.1 - 3.5e-40 137.6 19.3 4.6e-40 137.3 13.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family HSF_DNA-bind PF00447.12 OAJ24482.1 - 5.5e-34 116.4 0.1 5.5e-34 116.4 0.0 2.6 2 0 0 2 2 2 1 HSF-type DNA-binding FA_desaturase PF00487.19 OAJ24483.1 - 2.9e-27 95.7 24.0 8.4e-27 94.2 16.6 1.7 1 1 0 1 1 1 1 Fatty acid desaturase Metallophos PF00149.23 OAJ24484.1 - 9.3e-30 103.5 0.0 1.2e-28 99.8 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 OAJ24484.1 - 1.6e-20 72.4 1.0 1.7e-14 53.2 0.1 2.6 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 OAJ24484.1 - 2.9e-14 51.9 0.9 2.5e-06 26.8 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ24484.1 - 5.4e-09 35.2 3.3 0.0021 17.8 0.0 4.1 5 0 0 5 5 5 3 Tetratricopeptide repeat PPP5 PF08321.7 OAJ24484.1 - 7.1e-09 35.5 0.0 2.5e-05 24.2 0.0 2.4 1 1 1 2 2 2 2 PPP5 TPR repeat region TPR_17 PF13431.1 OAJ24484.1 - 0.00075 19.5 0.2 0.04 14.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ24484.1 - 0.0089 16.6 1.4 0.11 13.2 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ24484.1 - 0.0094 15.7 0.6 0.043 13.6 0.0 2.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 OAJ24484.1 - 0.019 14.0 0.0 0.68 8.9 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ24484.1 - 0.096 13.3 0.3 5.4 7.9 0.0 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat CoA_trans PF01144.18 OAJ24486.1 - 1.6e-105 351.1 0.2 1.4e-63 213.9 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 OAJ24486.1 - 0.12 12.0 0.1 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Involucrin_N PF10583.4 OAJ24486.1 - 0.19 12.0 0.5 0.38 11.1 0.3 1.5 1 0 0 1 1 1 0 Involucrin of squamous epithelia N-terminus Y_phosphatase2 PF03162.8 OAJ24487.1 - 1.9e-30 105.4 0.0 1.1e-23 83.4 0.0 3.1 3 0 0 3 3 3 3 Tyrosine phosphatase family Sds3 PF08598.6 OAJ24489.1 - 1.3e-22 80.3 5.2 1.3e-22 80.3 3.6 1.9 2 1 0 2 2 2 1 Sds3-like MULE PF10551.4 OAJ24490.1 - 7.4e-11 42.0 0.0 1.6e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ24490.1 - 0.003 16.1 0.0 0.0051 15.4 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family SWIM PF04434.12 OAJ24490.1 - 0.013 14.9 1.5 0.032 13.7 0.0 2.3 2 0 0 2 2 2 0 SWIM zinc finger FAR1 PF03101.10 OAJ24490.1 - 0.017 15.6 0.1 0.068 13.6 0.1 2.0 1 0 0 1 1 1 0 FAR1 DNA-binding domain MAPEG PF01124.13 OAJ24491.1 - 5.2e-26 90.7 0.7 6.1e-26 90.5 0.5 1.1 1 0 0 1 1 1 1 MAPEG family Peptidase_M3 PF01432.15 OAJ24491.1 - 0.29 10.1 0.9 7.3 5.4 0.3 2.0 1 1 1 2 2 2 0 Peptidase family M3 MFS_1 PF07690.11 OAJ24492.1 - 2.6e-35 121.8 11.6 2.6e-35 121.8 8.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ24492.1 - 2.5e-07 29.6 18.4 5.9e-07 28.4 4.1 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 OAJ24492.1 - 0.0029 15.8 0.9 0.0049 15.1 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Nuc_H_symport PF03825.11 OAJ24492.1 - 0.011 14.5 7.5 0.024 13.4 0.5 2.4 2 0 0 2 2 2 0 Nucleoside H+ symporter MFS_3 PF05977.8 OAJ24492.1 - 1.1 7.3 8.6 0.18 9.8 0.8 2.4 2 0 0 2 2 2 0 Transmembrane secretion effector Ada_Zn_binding PF02805.11 OAJ24493.1 - 8.6e-20 70.1 7.6 1.6e-19 69.2 5.3 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 OAJ24493.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family ADIP PF11559.3 OAJ24494.1 - 6.9e-19 68.2 4.4 1.2e-18 67.4 3.0 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Myosin_tail_1 PF01576.14 OAJ24494.1 - 0.0011 16.8 5.7 0.0015 16.4 4.0 1.1 1 0 0 1 1 1 1 Myosin tail CCDC144C PF14915.1 OAJ24494.1 - 0.0033 16.3 7.2 0.0052 15.7 5.0 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region ERM PF00769.14 OAJ24494.1 - 0.015 14.8 8.0 0.031 13.8 5.6 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF2360 PF10152.4 OAJ24494.1 - 1.6 9.0 4.6 15 5.8 3.2 2.2 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DivIVA PF05103.8 OAJ24494.1 - 10 6.2 9.5 2.9 7.9 3.7 2.0 2 0 0 2 2 2 0 DivIVA protein Asp PF00026.18 OAJ24495.1 - 6.6e-64 216.1 0.1 8.2e-64 215.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ24495.1 - 1.4e-06 28.3 0.3 3.3e-06 27.1 0.2 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAJ24495.1 - 2.7e-06 27.7 1.8 0.0013 19.1 0.0 3.4 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 OAJ24495.1 - 0.023 14.5 0.5 0.076 12.8 0.0 2.1 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease adh_short PF00106.20 OAJ24496.1 - 9.3e-32 110.2 1.2 1.7e-31 109.3 0.8 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ24496.1 - 7.4e-15 55.0 4.7 6.3e-14 52.0 2.3 2.7 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 OAJ24496.1 - 1.2e-10 41.5 0.0 1.7e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAJ24496.1 - 1.3e-05 24.8 0.2 8.6e-05 22.0 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ24496.1 - 0.00012 22.1 0.9 0.00028 20.9 0.6 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAJ24496.1 - 0.00045 19.0 0.3 0.00066 18.4 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 OAJ24496.1 - 0.0025 16.7 0.1 0.0037 16.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Urocanase PF01175.13 OAJ24496.1 - 0.0077 14.3 0.0 0.01 13.9 0.0 1.1 1 0 0 1 1 1 1 Urocanase FAD_binding_3 PF01494.14 OAJ24496.1 - 0.019 14.0 0.2 0.03 13.3 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 OAJ24496.1 - 0.043 13.4 0.2 0.085 12.4 0.2 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IncA PF04156.9 OAJ24496.1 - 0.093 12.3 1.0 0.26 10.8 0.4 1.9 2 0 0 2 2 2 0 IncA protein ELFV_dehydrog PF00208.16 OAJ24496.1 - 0.13 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RAI1 PF08652.6 OAJ24497.1 - 7.9e-19 67.2 0.0 1.9e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Lipase_GDSL_2 PF13472.1 OAJ24504.1 - 1.1e-06 28.8 0.3 1.5e-06 28.4 0.2 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 OAJ24504.1 - 9.9e-06 25.5 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DCR PF14047.1 OAJ24504.1 - 0.12 12.6 0.2 0.6 10.4 0.0 2.1 2 0 0 2 2 2 0 Dppa2/4 conserved region E1-E2_ATPase PF00122.15 OAJ24505.1 - 2.8e-49 167.2 1.3 4.4e-49 166.5 0.9 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 OAJ24505.1 - 1.9e-39 136.2 0.2 2.9e-32 112.8 0.0 3.6 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase HMA PF00403.21 OAJ24505.1 - 5.8e-17 61.5 0.0 8.2e-10 38.6 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 OAJ24505.1 - 1.7e-13 51.1 0.0 1.7e-12 47.8 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ24505.1 - 0.016 14.8 0.4 0.07 12.7 0.4 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DnaJ PF00226.26 OAJ24506.1 - 6.6e-14 51.4 0.8 1.4e-13 50.3 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain Ras PF00071.17 OAJ24507.1 - 1.9e-56 189.9 0.3 2.4e-56 189.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ24507.1 - 1.2e-18 67.7 0.1 1.7e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ24507.1 - 2.6e-13 49.6 0.2 3.1e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ24507.1 - 6.3e-07 29.0 0.1 1.2e-06 28.0 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 OAJ24507.1 - 0.00018 20.7 0.1 0.00022 20.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 OAJ24507.1 - 0.0021 17.2 0.2 0.0024 17.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Sugar_tr PF00083.19 OAJ24508.1 - 1.8e-114 382.8 15.6 2.5e-114 382.3 10.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ24508.1 - 9.3e-27 93.6 33.5 5.4e-26 91.1 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MIT PF04212.13 OAJ24510.1 - 1.1e-05 25.1 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain SH3BP5 PF05276.9 OAJ24510.1 - 0.31 10.3 0.1 0.47 9.7 0.1 1.2 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Myosin_head PF00063.16 OAJ24511.1 - 8.9e-227 754.4 3.0 1.5e-226 753.7 2.1 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 OAJ24511.1 - 2e-41 141.5 0.0 3.8e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 OAJ24511.1 - 1.9e-10 39.9 0.2 4e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ24511.1 - 6.5e-10 38.4 0.1 1.6e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ24511.1 - 1.3e-05 24.6 0.0 4.1e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 OAJ24511.1 - 0.0083 16.2 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAJ24511.1 - 0.037 13.1 0.1 0.078 12.0 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 OAJ24511.1 - 0.051 12.8 0.4 5.1 6.3 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_17 PF13207.1 OAJ24511.1 - 0.055 14.2 0.0 0.18 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAJ24511.1 - 0.17 11.5 0.1 0.34 10.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain IQ PF00612.22 OAJ24511.1 - 4.1 7.3 6.6 1.5 8.6 1.0 2.6 1 1 1 2 2 2 0 IQ calmodulin-binding motif Peptidase_C50 PF03568.12 OAJ24512.1 - 6.9e-75 252.1 0.0 9.5e-75 251.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C50 TPR_2 PF07719.12 OAJ24512.1 - 1.7 8.7 10.3 3.2 7.9 0.6 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ24512.1 - 6.9 6.3 11.9 0.57 9.8 1.4 4.0 5 0 0 5 5 5 0 TPR repeat Ribosomal_L6 PF00347.18 OAJ24513.1 - 6.4e-19 68.2 0.0 1e-12 48.3 0.0 3.6 4 0 0 4 4 4 2 Ribosomal protein L6 MULE PF10551.4 OAJ24514.1 - 5.4e-19 68.1 0.1 1.4e-18 66.8 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 OAJ24514.1 - 9e-05 22.9 0.1 0.00017 22.0 0.1 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain STAT_int PF02865.12 OAJ24514.1 - 1.1 9.1 5.9 0.46 10.4 0.4 2.6 3 0 0 3 3 3 0 STAT protein, protein interaction domain MULE PF10551.4 OAJ24516.1 - 4.7e-17 61.9 0.0 1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ24516.1 - 4.8e-13 48.4 0.0 1.1e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Transposase, Mutator family FAR1 PF03101.10 OAJ24516.1 - 1.3e-08 35.2 0.8 4e-08 33.6 0.5 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain SWIM PF04434.12 OAJ24516.1 - 0.0021 17.4 0.1 0.0047 16.3 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger DDE_Tnp_IS240 PF13610.1 OAJ24516.1 - 0.0023 17.9 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 DDE domain rve PF00665.21 OAJ24516.1 - 0.0046 17.0 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_ISL3 PF01610.12 OAJ24516.1 - 0.0067 16.0 0.1 0.11 12.0 0.0 2.1 1 1 1 2 2 2 1 Transposase Striatin PF08232.7 OAJ24517.1 - 6.4e-18 65.3 1.0 1.1e-12 48.4 0.3 2.3 1 1 1 2 2 2 2 Striatin family G-alpha PF00503.15 OAJ24517.1 - 0.051 12.2 0.0 0.076 11.6 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit PBP_like_2 PF12849.2 OAJ24518.1 - 0.0021 17.5 0.9 0.0027 17.2 0.5 1.3 1 1 0 1 1 1 1 PBP superfamily domain ADIP PF11559.3 OAJ24518.1 - 0.0071 16.2 3.6 0.0071 16.2 2.5 1.5 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF342 PF03961.8 OAJ24518.1 - 0.052 11.9 0.3 0.065 11.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Filament PF00038.16 OAJ24518.1 - 0.27 10.6 6.4 0.35 10.3 4.4 1.1 1 0 0 1 1 1 0 Intermediate filament protein DUF591 PF04569.9 OAJ24518.1 - 0.46 10.5 5.8 1.7 8.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function SPATA24 PF15175.1 OAJ24518.1 - 0.61 9.7 3.6 8.6 6.0 0.3 2.2 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 NUFIP1 PF10453.4 OAJ24519.1 - 1.7e-11 43.4 0.3 3.9e-11 42.2 0.2 1.6 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) SR-25 PF10500.4 OAJ24519.1 - 1.4 8.2 29.0 2.9 7.3 16.0 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SAPS PF04499.10 OAJ24519.1 - 1.8 7.1 6.5 2.4 6.7 4.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 OAJ24519.1 - 3.7 5.3 26.7 5 4.9 18.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 OAJ24519.1 - 6.2 4.7 16.9 8.4 4.2 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PLDc_2 PF13091.1 OAJ24520.1 - 1.5e-11 44.1 0.0 2e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 OAJ24520.1 - 4.1e-05 23.2 4.2 0.085 12.6 0.0 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif NIPSNAP PF07978.8 OAJ24525.1 - 1.4e-35 121.3 2.5 5.5e-28 96.9 0.2 2.2 2 0 0 2 2 2 2 NIPSNAP DUF718 PF05336.8 OAJ24525.1 - 0.012 15.4 1.6 0.013 15.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF718) Mito_carr PF00153.22 OAJ24526.1 - 8e-68 224.2 3.2 5e-23 80.6 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Carboxyl_trans PF01039.17 OAJ24527.1 - 5.2e-141 470.3 0.0 6.7e-141 470.0 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ACCA PF03255.9 OAJ24527.1 - 0.036 13.6 0.2 5.5 6.5 0.0 2.7 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ECH PF00378.15 OAJ24527.1 - 0.19 10.8 0.8 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase family CLPTM1 PF05602.7 OAJ24528.1 - 2.2e-91 306.7 1.1 1.5e-89 300.7 0.5 3.0 2 1 0 2 2 2 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 OAJ24528.1 - 5.6e-09 35.4 0.9 2.2e-07 30.3 0.4 2.6 2 0 0 2 2 2 1 PQ loop repeat DUF2417 PF10329.4 OAJ24529.1 - 4.7e-14 52.3 0.0 7.3e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) DUF3951 PF13131.1 OAJ24529.1 - 1.5 8.6 0.0 1.5 8.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3951) DUF4131 PF13567.1 OAJ24529.1 - 4.1 6.7 6.8 18 4.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PDCD2_C PF04194.8 OAJ24531.1 - 2.1e-24 85.9 0.4 1e-21 77.2 0.0 3.5 4 1 0 4 4 4 2 Programmed cell death protein 2, C-terminal putative domain NOA36 PF06524.7 OAJ24531.1 - 0.07 12.3 22.9 0.039 13.2 4.1 2.3 2 0 0 2 2 2 0 NOA36 protein Nucleoplasmin PF03066.10 OAJ24531.1 - 0.36 10.3 22.4 1.2 8.5 3.5 2.6 2 0 0 2 2 2 0 Nucleoplasmin DUF4611 PF15387.1 OAJ24531.1 - 1.7 8.8 19.5 1.2 9.3 4.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.7 OAJ24531.1 - 7.4 6.1 27.2 4.3 6.9 6.8 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.4 OAJ24531.1 - 9.7 4.7 31.8 1.7 7.2 4.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Glutaredoxin PF00462.19 OAJ24532.1 - 3.3e-18 65.4 0.0 5.6e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin NAD_binding_8 PF13450.1 OAJ24533.1 - 1.3e-07 31.5 0.0 3.7e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAJ24533.1 - 0.004 17.2 0.0 0.25 11.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ24533.1 - 0.0054 16.6 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAJ24533.1 - 0.026 13.4 0.6 0.061 12.1 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 OAJ24533.1 - 0.052 13.9 0.0 17 5.8 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MukE PF04288.8 OAJ24533.1 - 0.13 11.0 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 MukE-like family HI0933_like PF03486.9 OAJ24533.1 - 0.16 10.3 0.1 0.52 8.7 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Met_10 PF02475.11 OAJ24534.1 - 1.2e-49 168.6 0.0 6.2e-40 136.9 0.0 2.3 2 0 0 2 2 2 2 Met-10+ like-protein PBD PF00786.23 OAJ24535.1 - 6.6e-05 23.2 0.0 0.00032 21.0 0.0 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain F-box PF00646.28 OAJ24536.1 - 2.3e-07 30.2 0.1 3.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ24536.1 - 0.00021 20.9 0.1 0.00043 19.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like DUF443 PF04276.7 OAJ24538.1 - 0.27 10.6 9.5 0.075 12.4 1.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF443) PhoD PF09423.5 OAJ24539.1 - 0.00049 18.8 0.0 0.019 13.5 0.1 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Dehydrin PF00257.14 OAJ24539.1 - 0.014 15.6 0.3 0.03 14.6 0.2 1.5 1 0 0 1 1 1 0 Dehydrin F-box-like PF12937.2 OAJ24540.1 - 1.3e-05 24.8 0.1 2.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ24540.1 - 0.0013 18.2 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 OAJ24540.1 - 0.0037 16.9 0.6 0.0066 16.1 0.4 1.7 1 1 0 1 1 1 1 F-box-like domain E3_binding PF02817.12 OAJ24540.1 - 0.065 12.8 0.3 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 e3 binding domain LIP PF03583.9 OAJ24541.1 - 6.8e-44 150.2 0.5 2.3e-42 145.2 0.3 2.0 1 1 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 OAJ24541.1 - 0.00052 19.7 0.0 0.001 18.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 OAJ24541.1 - 0.0099 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Cutinase DUF2920 PF11144.3 OAJ24541.1 - 0.02 13.9 0.0 0.12 11.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) Complex1_LYR PF05347.10 OAJ24542.1 - 2.1e-05 24.2 0.7 7.4e-05 22.4 0.5 1.9 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAJ24542.1 - 0.0016 18.5 0.5 0.0046 17.1 0.4 1.8 1 1 0 1 1 1 1 Complex1_LYR-like Methyltransf_23 PF13489.1 OAJ24542.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Rhodanese PF00581.15 OAJ24542.1 - 0.083 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Rhodanese-like domain TehB PF03848.9 OAJ24542.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB TFIIF_alpha PF05793.7 OAJ24543.1 - 0.019 13.3 2.5 0.023 13.0 1.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Spt5_N PF11942.3 OAJ24543.1 - 0.035 14.7 4.0 0.035 14.7 2.8 1.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF445 PF04286.7 OAJ24543.1 - 0.038 13.5 0.0 0.044 13.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Glyco_hydro_85 PF03644.8 OAJ24545.1 - 4.6e-53 180.3 0.0 6.3e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 SBF PF01758.11 OAJ24547.1 - 0.48 9.8 8.0 0.26 10.6 2.9 2.4 2 1 0 2 2 2 0 Sodium Bile acid symporter family PH PF00169.24 OAJ24553.1 - 0.0022 18.1 0.0 0.005 17.0 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 OAJ24553.1 - 0.0085 16.3 0.0 0.029 14.6 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain DUF2207 PF09972.4 OAJ24554.1 - 2 6.9 12.2 2.2 6.7 8.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SPX PF03105.14 OAJ24556.1 - 1e-46 159.9 1.0 1.4e-46 159.5 0.7 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 OAJ24556.1 - 9.1e-31 107.2 37.7 1.2e-30 106.7 26.1 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 OAJ24556.1 - 2.7e-21 75.5 37.9 3.4e-14 52.1 12.1 2.2 1 1 1 2 2 2 2 Citrate transporter DEAD PF00270.24 OAJ24557.1 - 3e-19 69.1 0.1 3.7e-18 65.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Metallophos PF00149.23 OAJ24557.1 - 9.2e-18 64.3 0.1 2.5e-16 59.6 0.0 2.6 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Helicase_C PF00271.26 OAJ24557.1 - 3.8e-15 55.5 0.1 1.4e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Metallophos_C PF14008.1 OAJ24557.1 - 3.1e-13 49.5 0.0 8.7e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 OAJ24557.1 - 9.3e-07 27.7 0.0 2.8e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 PhoD-like phosphatase fn3 PF00041.16 OAJ24557.1 - 0.0033 17.5 1.3 0.0083 16.2 0.9 1.7 1 0 0 1 1 1 1 Fibronectin type III domain Metallophos_2 PF12850.2 OAJ24557.1 - 0.013 15.3 0.0 0.074 12.8 0.0 2.2 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain ResIII PF04851.10 OAJ24557.1 - 0.022 14.5 0.0 0.13 12.0 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RQC PF09382.5 OAJ24557.1 - 0.19 11.4 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 RQC domain Pex24p PF06398.6 OAJ24558.1 - 7.6e-26 90.7 3.3 7.6e-26 90.7 2.3 2.6 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin Rad21_Rec8_N PF04825.8 OAJ24560.1 - 5.7e-23 80.9 0.0 1.1e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 OAJ24560.1 - 8.2e-07 28.1 0.0 2.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein CCDC66 PF15236.1 OAJ24560.1 - 0.0044 16.6 0.6 0.0096 15.5 0.4 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 66 DUF2236 PF09995.4 OAJ24561.1 - 8.6e-23 80.8 3.2 8.6e-23 80.8 2.2 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Fcf1 PF04900.7 OAJ24562.1 - 6.9e-13 48.5 0.0 2.1e-12 47.0 0.0 1.8 1 1 0 1 1 1 1 Fcf1 CENP-U PF13097.1 OAJ24562.1 - 0.046 13.6 3.0 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit mRNA_triPase PF02940.10 OAJ24563.1 - 3.3e-45 154.4 0.1 3.9e-45 154.2 0.1 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain CPSF_A PF03178.10 OAJ24564.1 - 1.5e-61 208.2 0.0 2.5e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region Fer2 PF00111.22 OAJ24565.1 - 2.8e-10 39.7 0.4 5.1e-10 38.9 0.3 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain N2227 PF07942.7 OAJ24566.1 - 1.3e-87 293.2 0.0 1.8e-87 292.7 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 OAJ24566.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SNase PF00565.12 OAJ24567.1 - 4.8e-45 152.2 0.9 2.4e-17 63.1 0.0 7.2 7 0 0 7 7 7 5 Staphylococcal nuclease homologue TUDOR PF00567.19 OAJ24567.1 - 3.7e-20 71.9 0.0 7.1e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Tudor domain DUF4537 PF15057.1 OAJ24567.1 - 0.0062 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Agenet PF05641.7 OAJ24567.1 - 0.053 13.6 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 Agenet domain WD40 PF00400.27 OAJ24568.1 - 1.7e-60 198.8 19.6 5.4e-12 45.1 1.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 OAJ24568.1 - 3.2e-07 29.7 0.0 0.0044 16.4 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Proteasome_A_N PF10584.4 OAJ24568.1 - 0.048 12.9 0.1 13 5.2 0.0 3.1 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Abhydrolase_1 PF00561.15 OAJ24569.1 - 2.1e-13 50.3 0.0 8.8e-12 45.0 0.0 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 OAJ24569.1 - 7.6e-13 48.2 0.0 1.7e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 OAJ24569.1 - 6.1e-07 29.5 2.2 2e-06 27.8 0.4 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF836 PF05768.9 OAJ24570.1 - 3.2e-10 40.1 0.0 4.3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 OAJ24570.1 - 0.0084 16.2 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Tfb2 PF03849.9 OAJ24571.1 - 6.6e-27 94.1 0.0 7.8e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 UDPGP PF01704.13 OAJ24572.1 - 1.3e-24 86.5 0.0 3.9e-16 58.5 0.0 2.7 2 1 1 3 3 3 2 UTP--glucose-1-phosphate uridylyltransferase Prp18 PF02840.10 OAJ24573.1 - 1.3e-57 193.7 0.0 2.2e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.6 OAJ24573.1 - 3.4e-12 45.4 3.7 7.8e-12 44.2 2.5 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like RabGAP-TBC PF00566.13 OAJ24578.1 - 2.2e-19 69.7 0.0 5.6e-19 68.4 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain UPF0233 PF06781.7 OAJ24580.1 - 0.047 13.3 0.6 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) OppC_N PF12911.2 OAJ24580.1 - 0.07 12.5 0.1 0.18 11.1 0.1 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF2029 PF09594.5 OAJ24580.1 - 5.2 6.4 13.4 0.12 11.8 4.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) Rifin_STEVOR PF02009.11 OAJ24580.1 - 5.8 6.4 8.9 45 3.5 6.2 2.0 1 1 0 1 1 1 0 Rifin/stevor family C2 PF00168.25 OAJ24581.1 - 9.6e-11 41.3 0.0 2.4e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 C2 domain DUF4597 PF15366.1 OAJ24581.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Bac_luciferase PF00296.15 OAJ24582.1 - 2.4e-62 210.7 0.8 3.2e-62 210.4 0.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Staphylcoagulse PF04022.7 OAJ24584.1 - 0.057 12.7 0.9 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Staphylocoagulase repeat Ras PF00071.17 OAJ24585.1 - 1e-44 151.7 0.0 4.7e-42 143.1 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 OAJ24585.1 - 2.2e-20 73.3 0.0 3.5e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ24585.1 - 1.6e-11 43.7 0.0 2.7e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ24585.1 - 3.5e-05 23.0 0.0 5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 OAJ24585.1 - 0.037 13.9 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 OAJ24585.1 - 0.083 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit cNMP_binding PF00027.24 OAJ24586.1 - 1.4e-39 133.7 0.0 5.9e-20 70.8 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 OAJ24586.1 - 9.6e-13 47.3 0.2 1.9e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Med15 PF09606.5 OAJ24586.1 - 0.0017 16.6 12.4 0.0017 16.6 8.6 1.8 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal SEFIR PF08357.6 OAJ24586.1 - 0.16 11.9 1.5 28 4.7 2.0 2.2 2 0 0 2 2 2 0 SEFIR domain Ndc1_Nup PF09531.5 OAJ24586.1 - 1.1 7.5 3.5 1.6 7.0 2.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Activator_LAG-3 PF11498.3 OAJ24586.1 - 5.1 5.7 28.4 9.5 4.8 19.7 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 S4 PF01479.20 OAJ24587.1 - 3e-13 48.9 0.1 5.1e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 OAJ24587.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 S4 domain SAPS PF04499.10 OAJ24587.1 - 0.091 11.3 0.2 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Secretin_N_2 PF07655.8 OAJ24587.1 - 0.55 10.6 0.0 0.55 10.6 0.0 3.4 3 0 0 3 3 3 0 Secretin N-terminal domain TPR_12 PF13424.1 OAJ24588.1 - 0.00062 19.6 10.6 0.18 11.7 4.2 4.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ24588.1 - 0.0017 18.2 4.3 0.61 10.0 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF3856 PF12968.2 OAJ24588.1 - 0.018 14.8 1.8 4.9 6.9 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) HTH_Mga PF08280.6 OAJ24588.1 - 0.081 12.7 0.6 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain TPR_14 PF13428.1 OAJ24588.1 - 2.3 9.0 5.8 29 5.6 0.4 4.8 5 1 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.27 OAJ24589.1 - 2.8e-12 46.0 1.1 0.00037 20.2 0.2 3.3 2 1 0 2 2 2 2 WD domain, G-beta repeat PQQ_3 PF13570.1 OAJ24589.1 - 0.05 13.8 0.3 0.38 11.0 0.3 2.1 2 0 0 2 2 2 0 PQQ-like domain CRT10 PF08728.5 OAJ24589.1 - 0.16 9.9 0.0 0.21 9.5 0.0 1.1 1 0 0 1 1 1 0 CRT10 PARP PF00644.15 OAJ24590.1 - 5.8e-05 22.6 0.2 0.00044 19.7 0.2 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Pkinase PF00069.20 OAJ24591.1 - 6.4e-21 74.6 0.0 1.3e-11 44.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ24591.1 - 2.2e-09 36.7 0.0 0.00014 21.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase WD40 PF00400.27 OAJ24592.1 - 2.6e-54 179.2 17.8 2.6e-10 39.7 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 OAJ24592.1 - 0.00017 19.9 0.0 0.0015 16.8 0.0 2.0 2 0 0 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.3 OAJ24592.1 - 0.0022 16.2 1.0 2.8 5.9 0.0 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 OAJ24592.1 - 0.041 13.6 0.0 0.42 10.4 0.0 2.6 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region SH3_6 PF12913.2 OAJ24592.1 - 0.095 11.9 0.0 0.72 9.1 0.0 2.3 2 0 0 2 2 2 0 SH3 domain of the SH3b1 type PD40 PF07676.7 OAJ24592.1 - 0.15 11.7 1.7 26 4.6 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 OAJ24592.1 - 0.93 9.8 8.0 1.2 9.5 0.5 4.0 3 1 0 3 3 3 0 PQQ-like domain SH3_1 PF00018.23 OAJ24593.1 - 7.2e-14 50.9 0.2 1.4e-13 49.9 0.2 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 OAJ24593.1 - 2.2e-12 47.0 0.0 5e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.1 OAJ24593.1 - 1.1e-11 44.0 0.1 2.2e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 OAJ24593.1 - 1.2e-08 34.6 0.0 1.9e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 OAJ24593.1 - 2e-08 33.5 0.0 4.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 OAJ24593.1 - 6.8e-06 26.1 0.1 1.5e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 OAJ24593.1 - 0.00041 20.3 0.2 0.00076 19.4 0.2 1.4 1 0 0 1 1 1 1 Ste50p, sterile alpha motif PH_11 PF15413.1 OAJ24593.1 - 0.19 12.0 0.2 0.52 10.5 0.1 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Nucleoplasmin PF03066.10 OAJ24594.1 - 0.44 10.0 10.0 0.85 9.1 6.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin Nucleo_P87 PF07267.6 OAJ24594.1 - 1.5 7.4 7.4 2.5 6.6 5.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.7 OAJ24594.1 - 9.7 5.3 9.2 16 4.6 6.4 1.3 1 0 0 1 1 1 0 NOA36 protein Gtr1_RagA PF04670.7 OAJ24595.1 - 1.5e-82 276.2 0.0 2.1e-82 275.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 OAJ24595.1 - 0.00017 20.9 0.0 0.00036 19.9 0.0 1.6 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 OAJ24595.1 - 0.00026 20.9 0.0 0.00054 19.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 OAJ24595.1 - 0.00033 19.9 0.0 0.00051 19.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 OAJ24595.1 - 0.0018 18.7 0.0 0.0041 17.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 OAJ24595.1 - 0.0056 16.1 0.7 0.025 14.0 0.1 2.3 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 OAJ24595.1 - 0.033 13.1 0.0 0.069 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 OAJ24595.1 - 0.093 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter TPR_MLP1_2 PF07926.7 OAJ24596.1 - 0.0043 16.7 35.0 0.025 14.3 16.3 2.9 1 1 2 3 3 3 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 OAJ24596.1 - 0.0058 16.4 30.2 0.18 11.6 6.5 2.5 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.13 OAJ24596.1 - 0.0072 16.0 0.8 0.0072 16.0 0.5 4.2 3 2 1 4 4 4 2 Homeobox associated leucine zipper Orthopox_A5L PF06193.6 OAJ24596.1 - 0.013 15.4 9.5 0.56 10.1 6.6 2.3 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like Erythro-docking PF09277.6 OAJ24596.1 - 0.036 13.7 0.5 0.1 12.3 0.4 1.8 1 0 0 1 1 1 0 Erythronolide synthase, docking AAA_13 PF13166.1 OAJ24596.1 - 0.037 12.4 14.0 0.048 12.1 9.7 1.1 1 0 0 1 1 1 0 AAA domain TraF_2 PF13729.1 OAJ24596.1 - 0.14 10.9 1.2 0.24 10.1 0.7 1.7 1 1 0 1 1 1 0 F plasmid transfer operon, TraF, protein Mt_ATP-synt_B PF05405.9 OAJ24596.1 - 0.21 11.0 22.5 0.015 14.7 6.9 2.1 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Peptidase_S49 PF01343.13 OAJ24596.1 - 0.23 11.2 7.7 0.34 10.6 4.1 1.9 1 1 1 2 2 2 0 Peptidase family S49 ApoO PF09769.4 OAJ24596.1 - 0.57 9.8 3.4 0.63 9.7 0.4 2.2 1 1 1 2 2 2 0 Apolipoprotein O COG5 PF10392.4 OAJ24596.1 - 0.6 10.0 11.8 0.11 12.4 4.4 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Mnd1 PF03962.10 OAJ24596.1 - 0.6 9.7 28.7 0.71 9.5 6.3 2.6 1 1 2 3 3 3 0 Mnd1 family KaiC PF06745.8 OAJ24596.1 - 0.69 8.9 6.4 0.11 11.6 1.3 1.8 1 1 0 2 2 2 0 KaiC DUF479 PF04336.7 OAJ24596.1 - 1 9.5 6.2 0.19 11.8 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF479 Reo_sigmaC PF04582.7 OAJ24596.1 - 1.1 8.3 6.2 2.3 7.3 3.9 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GAS PF13851.1 OAJ24596.1 - 1.1 8.4 26.6 0.52 9.4 12.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DNA_topoisoIV PF00521.15 OAJ24596.1 - 1.4 7.6 10.1 1.9 7.2 7.0 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF3584 PF12128.3 OAJ24596.1 - 1.5 6.0 29.4 1.8 5.8 20.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FUSC PF04632.7 OAJ24596.1 - 1.7 6.9 15.2 2.1 6.6 10.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tropomyosin_1 PF12718.2 OAJ24596.1 - 1.8 8.4 33.1 0.14 12.0 10.1 2.4 1 1 1 2 2 2 0 Tropomyosin like DASH_Dam1 PF08653.5 OAJ24596.1 - 2 8.2 6.5 2.5 7.9 0.1 3.5 3 1 2 5 5 4 0 DASH complex subunit Dam1 TBD PF12845.2 OAJ24596.1 - 4.2 7.0 13.2 0.049 13.1 1.2 2.8 3 0 0 3 3 3 0 TBD domain DUF3347 PF11827.3 OAJ24596.1 - 5.4 6.9 19.0 0.37 10.7 5.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) DUF972 PF06156.8 OAJ24596.1 - 5.7 7.3 20.8 3.3 8.1 2.8 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF87 PF01935.12 OAJ24596.1 - 6.3 6.5 11.6 1.4 8.7 4.0 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF87 Ax_dynein_light PF10211.4 OAJ24596.1 - 6.5 6.5 27.4 0.69 9.7 7.4 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Allexi_40kDa PF05549.6 OAJ24596.1 - 8.9 5.5 12.5 7.2 5.8 4.1 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein Ank_2 PF12796.2 OAJ24597.1 - 3.5e-21 75.3 1.5 1.5e-09 38.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ24597.1 - 8.2e-17 60.0 14.1 3.5e-07 29.7 0.7 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 OAJ24597.1 - 5.7e-13 48.9 4.0 0.00026 21.4 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ24597.1 - 9.2e-12 44.8 5.1 2.8e-06 27.3 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ24597.1 - 2.9e-10 39.3 5.3 0.001 19.0 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat BAF1_ABF1 PF04684.8 OAJ24597.1 - 2.1 7.0 16.2 3.3 6.4 11.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Serinc PF03348.10 OAJ24597.1 - 3.1 6.4 4.6 4.5 5.8 3.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) UQ_con PF00179.21 OAJ24598.1 - 1e-38 131.9 0.0 1.4e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 OAJ24598.1 - 0.041 13.7 0.1 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 OAJ24598.1 - 0.049 13.3 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 UEV domain MFS_1 PF07690.11 OAJ24599.1 - 1.7e-20 73.0 38.8 2e-13 49.7 16.0 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 OAJ24599.1 - 1.8e-12 47.0 4.9 1.8e-12 47.0 3.4 2.6 2 1 0 2 2 2 1 Nodulin-like zf-CCHH PF10283.4 OAJ24599.1 - 0.026 14.3 2.3 0.049 13.4 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger (CX5CX6HX5H) motif DUF3464 PF11947.3 OAJ24599.1 - 0.29 10.5 2.6 1.4 8.3 1.8 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Lustrin_cystein PF14625.1 OAJ24599.1 - 0.88 9.6 2.7 1.6 8.9 1.9 1.3 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain 4HBT PF03061.17 OAJ24600.1 - 1e-07 31.9 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily zf-RING_6 PF14835.1 OAJ24600.1 - 0.094 12.5 1.9 0.33 10.7 1.1 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein ABC2_membrane PF01061.19 OAJ24606.1 - 1.9e-58 197.0 44.7 1.8e-32 112.2 16.9 3.0 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 OAJ24606.1 - 2.4e-32 110.6 0.2 5e-28 96.7 0.0 2.6 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 OAJ24606.1 - 7e-19 68.4 0.0 1.4e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 OAJ24606.1 - 3.7e-06 27.0 0.4 3.8e-05 23.7 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 OAJ24606.1 - 3.8e-05 22.9 0.0 6.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 OAJ24606.1 - 8.9e-05 21.9 0.0 0.00039 19.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 OAJ24606.1 - 0.0057 16.2 0.1 0.011 15.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 OAJ24606.1 - 0.0059 16.0 0.4 0.01 15.3 0.3 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 OAJ24606.1 - 0.013 15.6 0.1 0.043 13.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 OAJ24606.1 - 0.024 15.4 0.0 0.058 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAJ24606.1 - 0.029 14.0 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 OAJ24606.1 - 0.032 13.7 0.4 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.1 OAJ24606.1 - 0.037 14.3 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 OAJ24606.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 OAJ24606.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 OAJ24606.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.1 OAJ24606.1 - 0.28 11.1 0.0 3.5 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain CobT PF06213.7 OAJ24608.1 - 0.12 11.4 11.1 0.16 11.0 7.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 OAJ24608.1 - 1.8 6.3 10.6 2.5 5.9 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family Cytochrom_c3_2 PF14537.1 OAJ24608.1 - 2.2 8.6 12.1 0.048 13.9 1.7 2.5 2 0 0 2 2 2 0 Cytochrome c3 CDC45 PF02724.9 OAJ24608.1 - 5.4 4.9 8.1 6.8 4.5 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DDE_1 PF03184.14 OAJ24609.1 - 4.8e-30 104.3 0.0 8.5e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Caldesmon PF02029.10 OAJ24609.1 - 0.23 9.8 36.2 0.34 9.2 25.1 1.3 1 0 0 1 1 1 0 Caldesmon DUF572 PF04502.8 OAJ24609.1 - 5.7 6.0 30.5 8 5.5 21.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Borrelia_P83 PF05262.6 OAJ24609.1 - 5.8 5.0 34.0 7.7 4.6 23.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_13 PF13166.1 OAJ24609.1 - 6.1 5.1 19.8 8.5 4.6 13.7 1.2 1 0 0 1 1 1 0 AAA domain Spore_coat_CotO PF14153.1 OAJ24610.1 - 2.1e-05 24.0 18.5 2.6e-05 23.7 12.8 1.1 1 0 0 1 1 1 1 Spore coat protein CotO Ycf1 PF05758.7 OAJ24610.1 - 0.00043 18.1 13.4 0.00043 18.1 9.3 1.0 1 0 0 1 1 1 1 Ycf1 Mitofilin PF09731.4 OAJ24610.1 - 0.0016 17.2 15.5 0.0016 17.2 10.8 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Med15 PF09606.5 OAJ24610.1 - 0.0086 14.3 35.3 0.0093 14.2 24.5 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal SAPS PF04499.10 OAJ24610.1 - 0.012 14.2 10.6 0.011 14.3 7.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 OAJ24610.1 - 0.012 14.1 14.8 0.013 14.0 10.3 1.2 1 0 0 1 1 1 0 Daxx Family Caldesmon PF02029.10 OAJ24610.1 - 0.013 13.9 19.4 0.017 13.5 13.4 1.1 1 0 0 1 1 1 0 Caldesmon Hid1 PF12722.2 OAJ24610.1 - 0.015 13.0 12.7 0.015 13.0 8.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 OAJ24610.1 - 0.037 12.2 26.6 0.04 12.1 18.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.9 OAJ24610.1 - 0.056 11.4 15.7 0.058 11.4 10.9 1.2 1 0 0 1 1 1 0 CDC45-like protein CDC73 PF05179.9 OAJ24610.1 - 0.084 12.2 11.6 0.089 12.1 8.1 1.2 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family BAF1_ABF1 PF04684.8 OAJ24610.1 - 0.085 11.6 23.1 0.096 11.5 16.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TAF4 PF05236.9 OAJ24610.1 - 0.11 11.7 21.4 0.2 10.9 14.8 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Dynamin_N PF00350.18 OAJ24610.1 - 0.12 12.1 3.8 0.15 11.9 2.6 1.3 1 0 0 1 1 1 0 Dynamin family Plasmodium_Vir PF05795.6 OAJ24610.1 - 0.17 11.0 5.4 0.17 11.0 3.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Otopetrin PF03189.8 OAJ24610.1 - 0.19 10.6 2.2 0.17 10.8 1.5 1.1 1 0 0 1 1 1 0 Otopetrin DUF4407 PF14362.1 OAJ24610.1 - 0.27 10.1 20.1 0.46 9.4 13.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF966 PF06136.8 OAJ24610.1 - 0.38 10.1 13.7 0.39 10.0 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) LMBR1 PF04791.11 OAJ24610.1 - 0.43 9.0 3.2 0.39 9.2 2.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein AUX_IAA PF02309.11 OAJ24610.1 - 0.83 9.3 16.6 1.1 8.9 11.5 1.3 1 0 0 1 1 1 0 AUX/IAA family Tim54 PF11711.3 OAJ24610.1 - 1.3 7.5 14.5 1.6 7.2 10.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sporozoite_P67 PF05642.6 OAJ24610.1 - 2.1 6.1 14.7 2.6 5.7 10.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tom37_C PF11801.3 OAJ24610.1 - 2.7 7.8 16.5 3.9 7.3 11.4 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Peptidase_S64 PF08192.6 OAJ24610.1 - 3.3 5.9 11.9 3.8 5.7 8.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Menin PF05053.8 OAJ24610.1 - 3.7 5.6 17.0 4.7 5.2 11.8 1.1 1 0 0 1 1 1 0 Menin UPF0560 PF10577.4 OAJ24610.1 - 5.5 5.1 17.9 6 4.9 12.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2146 PF10220.4 OAJ24610.1 - 5.7 4.7 14.6 6.9 4.5 10.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) CPSF100_C PF13299.1 OAJ24610.1 - 6.6 6.9 17.5 11 6.1 12.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3807 PF12720.2 OAJ24610.1 - 7.3 6.7 28.1 13 5.8 19.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) TFIIF_alpha PF05793.7 OAJ24610.1 - 8.2 4.6 29.1 13 3.9 20.2 1.3 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bud13 PF09736.4 OAJ24610.1 - 9.6 6.4 32.4 4.8 7.4 20.2 1.8 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex DUF2126 PF09899.4 OAJ24610.1 - 9.7 4.0 13.9 11 3.8 9.6 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Dicty_REP PF05086.7 OAJ24610.1 - 9.8 3.7 12.7 11 3.6 8.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Dppa2_A PF14049.1 OAJ24611.1 - 0.072 12.9 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Dppa2/4 conserved region in higher vertebrates CENP-T PF15511.1 OAJ24611.1 - 0.53 9.4 12.4 0.59 9.3 8.6 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SAM_adeno_trans PF01887.11 OAJ24612.1 - 0.091 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase Plasmodium_Vir PF05795.6 OAJ24612.1 - 0.14 11.3 0.8 0.21 10.7 0.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RRF PF01765.14 OAJ24613.1 - 0.0022 17.4 0.0 0.0026 17.2 0.0 1.1 1 0 0 1 1 1 1 Ribosome recycling factor TRH PF05438.7 OAJ24613.1 - 0.027 13.8 0.1 0.028 13.7 0.0 1.1 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) F-box-like PF12937.2 OAJ24614.1 - 8.4e-05 22.2 0.0 0.00023 20.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like DUF433 PF04255.9 OAJ24614.1 - 0.062 12.7 0.0 0.4 10.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF433) F-box-like PF12937.2 OAJ24615.1 - 0.029 14.0 1.6 0.035 13.8 0.1 1.9 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 OAJ24615.1 - 0.14 11.8 1.2 0.35 10.5 0.2 2.2 2 0 0 2 2 2 0 F-box domain TPR_11 PF13414.1 OAJ24618.1 - 3.6e-36 122.6 20.8 3.2e-14 52.3 2.5 5.4 4 1 1 5 5 5 5 TPR repeat TPR_2 PF07719.12 OAJ24618.1 - 3.7e-25 85.7 18.1 0.00036 20.2 0.1 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ24618.1 - 5.9e-23 79.4 12.8 0.0041 16.6 0.1 7.5 7 0 0 7 7 7 7 Tetratricopeptide repeat DnaJ PF00226.26 OAJ24618.1 - 1.1e-22 79.5 1.5 3.7e-22 77.8 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_16 PF13432.1 OAJ24618.1 - 2.5e-22 78.9 17.9 5.7e-05 23.6 0.1 6.2 3 2 2 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ24618.1 - 1e-18 67.3 19.9 1.8e-06 28.1 0.6 6.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ24618.1 - 1.7e-16 59.8 17.7 1.1e-05 25.2 0.2 5.7 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ24618.1 - 3e-16 58.4 17.3 0.0045 17.4 0.0 6.4 5 1 1 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 OAJ24618.1 - 1.1e-11 44.7 10.9 0.00025 21.1 0.2 3.7 2 1 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 OAJ24618.1 - 1.7e-08 33.6 13.9 0.32 10.8 0.1 7.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ24618.1 - 7.7e-08 32.0 11.9 0.014 15.2 0.4 5.0 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ24618.1 - 3.6e-06 27.0 17.9 0.26 11.8 0.0 7.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ24618.1 - 5.6e-06 25.7 10.5 0.3 10.9 0.1 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ24618.1 - 1.1e-05 25.2 8.6 13 6.2 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 OAJ24618.1 - 0.0003 20.5 11.3 0.014 15.2 0.1 4.8 4 1 1 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 OAJ24618.1 - 0.03 14.7 4.7 0.43 11.1 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1840 PF08895.6 OAJ24618.1 - 0.33 10.9 6.1 0.43 10.6 0.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) MIT PF04212.13 OAJ24618.1 - 1.6 8.6 17.7 6.7 6.6 0.0 4.9 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 OAJ24618.1 - 1.8 8.6 14.6 2.7 8.0 0.4 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat Glyco_hydro_45 PF02015.11 OAJ24619.1 - 1.7e-16 60.9 0.1 2.9e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 PUF PF00806.14 OAJ24620.1 - 2.9e-11 42.2 0.0 0.017 14.5 0.0 5.9 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat Bot1p PF12298.3 OAJ24621.1 - 5.6e-23 81.7 1.4 6.4e-23 81.5 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.2 OAJ24621.1 - 0.038 13.9 0.0 0.038 13.9 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal protein subunit L20 TLP-20 PF06088.6 OAJ24622.1 - 0.25 11.0 2.5 0.25 10.9 1.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Secretin_N_2 PF07655.8 OAJ24622.1 - 0.56 10.6 11.5 0.66 10.4 8.0 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Sigma70_ner PF04546.8 OAJ24622.1 - 0.85 9.1 3.0 0.88 9.1 2.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 OAJ24622.1 - 1.2 8.3 5.6 1.2 8.3 3.9 1.0 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 OAJ24622.1 - 2.4 6.0 7.6 2.4 6.0 5.3 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM110_C PF14160.1 OAJ24622.1 - 2.9 8.8 8.7 3.4 8.6 6.0 1.1 1 0 0 1 1 1 0 Centrosome-associated C terminus CAF-1_p150 PF11600.3 OAJ24622.1 - 7.9 5.7 10.5 8.9 5.6 7.3 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Apc5 PF12862.2 OAJ24623.1 - 0.051 13.4 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 OAJ24623.1 - 0.056 13.3 0.4 0.51 10.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3584 PF12128.3 OAJ24624.1 - 0.00012 19.6 0.7 0.00014 19.4 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CENP-Q PF13094.1 OAJ24624.1 - 0.0022 18.0 6.7 0.0032 17.5 4.6 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF883 PF05957.8 OAJ24624.1 - 0.003 17.8 8.3 0.003 17.8 5.7 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) Prominin PF05478.6 OAJ24624.1 - 0.016 12.7 0.1 0.02 12.4 0.1 1.0 1 0 0 1 1 1 0 Prominin TMCO5 PF14992.1 OAJ24624.1 - 0.016 14.3 1.5 0.021 13.9 1.0 1.1 1 0 0 1 1 1 0 TMCO5 family FPN1 PF06963.7 OAJ24624.1 - 0.021 13.2 0.1 0.027 12.8 0.0 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) ATP-synt_B PF00430.13 OAJ24624.1 - 0.077 12.8 10.2 0.16 11.8 7.1 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) RRF PF01765.14 OAJ24624.1 - 0.089 12.2 3.8 0.13 11.7 2.6 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Borrelia_P83 PF05262.6 OAJ24624.1 - 0.11 10.8 5.2 0.13 10.4 3.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TMPIT PF07851.8 OAJ24624.1 - 0.19 10.7 0.3 0.25 10.3 0.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein RR_TM4-6 PF06459.7 OAJ24624.1 - 0.32 10.8 5.2 0.39 10.5 3.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2317 PF10079.4 OAJ24624.1 - 0.71 8.4 4.9 0.9 8.0 3.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Peptidase_S49_N PF08496.5 OAJ24624.1 - 1 9.1 5.9 1.6 8.4 4.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal vATP-synt_E PF01991.13 OAJ24624.1 - 4 6.6 11.5 6.5 5.9 8.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Zw10 PF06248.8 OAJ24625.1 - 0.00099 17.3 0.8 0.079 11.0 0.0 2.8 3 0 0 3 3 3 2 Centromere/kinetochore Zw10 tRNA-synt_1b PF00579.20 OAJ24627.1 - 2.4e-20 72.8 0.0 9.9e-20 70.8 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Oxysterol_BP PF01237.13 OAJ24628.1 - 1.5e-53 181.5 0.0 2.3e-42 144.7 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein Sugar_tr PF00083.19 OAJ24630.1 - 6e-39 133.8 15.7 1.2e-38 132.8 10.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ24630.1 - 1.5e-24 86.4 27.3 6.9e-12 44.7 11.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1115 PF06544.7 OAJ24631.1 - 1.6e-11 44.0 0.0 2.2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF2638 PF10937.3 OAJ24631.1 - 0.063 14.2 0.9 0.14 13.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) Elong_Iki1 PF10483.4 OAJ24632.1 - 2.2e-11 43.6 0.2 5.9e-05 22.5 0.1 2.4 2 0 0 2 2 2 2 Elongator subunit Iki1 Acyl-CoA_dh_N PF02771.11 OAJ24633.1 - 6.4e-28 97.5 0.1 1.3e-27 96.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 OAJ24633.1 - 1.1e-23 84.0 0.0 2.2e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ24633.1 - 5.7e-18 64.1 0.0 1.3e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 OAJ24633.1 - 2.9e-05 24.3 0.0 2.9e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.19 OAJ24634.1 - 9e-46 155.6 5.0 9e-46 155.6 3.5 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAJ24634.1 - 2.5e-27 95.7 0.0 7.5e-27 94.1 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAJ24634.1 - 1.8e-22 79.9 2.6 1.8e-22 79.9 1.8 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ24634.1 - 5.3e-18 64.2 0.0 1e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Iso_dh PF00180.15 OAJ24635.1 - 7.3e-78 261.9 0.0 9.4e-78 261.5 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PTH2 PF01981.11 OAJ24636.1 - 2.2e-05 24.1 0.1 4e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 DUF1077 PF06417.7 OAJ24637.1 - 8e-48 160.9 0.4 1.1e-47 160.4 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF4658 PF15555.1 OAJ24637.1 - 0.33 10.8 2.0 2.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) Spc24 PF08286.6 OAJ24638.1 - 1.1 9.0 3.2 0.35 10.5 0.1 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 COesterase PF00135.23 OAJ24639.1 - 5.6e-81 272.8 0.1 2.6e-72 244.2 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ24639.1 - 1.1e-05 25.1 0.0 2.7e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold GFO_IDH_MocA PF01408.17 OAJ24640.1 - 7.8e-18 65.1 0.1 1.2e-17 64.5 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TMEM51 PF15345.1 OAJ24641.1 - 0.38 10.3 9.2 0.68 9.5 6.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 DUF1387 PF07139.6 OAJ24641.1 - 3.2 7.2 6.3 4.6 6.7 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Spt20 PF12090.3 OAJ24641.1 - 4.7 6.5 8.2 1.4 8.2 2.5 2.1 2 0 0 2 2 2 0 Spt20 family Ribonuclease_T2 PF00445.13 OAJ24642.1 - 3.8e-35 121.2 0.1 5.3e-35 120.7 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Peptidase_C54 PF03416.14 OAJ24643.1 - 1.7e-83 279.9 0.0 1.7e-82 276.7 0.0 2.2 1 1 0 1 1 1 1 Peptidase family C54 AAA_35 PF14516.1 OAJ24643.1 - 0.92 8.0 0.0 1.3 7.5 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain DUF4231 PF14015.1 OAJ24644.1 - 0.0026 17.7 1.0 0.0054 16.7 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) DUF4345 PF14248.1 OAJ24645.1 - 0.054 12.9 3.4 0.058 12.8 0.1 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4345) AAA_2 PF07724.9 OAJ24646.1 - 2.6e-43 147.9 0.0 4.2e-40 137.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 OAJ24646.1 - 9.8e-26 89.4 1.0 3.2e-25 87.8 0.0 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 OAJ24646.1 - 7e-20 71.5 0.0 2.8e-10 40.4 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAJ24646.1 - 4.6e-11 42.4 0.1 1.2e-07 31.3 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ24646.1 - 6.5e-11 42.1 0.0 8.5e-06 25.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 OAJ24646.1 - 1.4e-09 38.1 14.9 0.00041 20.3 0.0 5.3 4 3 1 6 6 5 3 AAA ATPase domain AAA_22 PF13401.1 OAJ24646.1 - 1.3e-07 31.8 1.4 0.0026 17.9 0.0 4.2 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 OAJ24646.1 - 2e-06 27.4 0.0 0.075 12.7 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 OAJ24646.1 - 8.9e-06 25.6 0.2 0.013 15.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 OAJ24646.1 - 1.6e-05 25.2 0.0 0.14 12.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 OAJ24646.1 - 6.8e-05 22.0 0.0 0.028 13.5 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 OAJ24646.1 - 7.6e-05 23.5 0.2 0.3 11.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.4 OAJ24646.1 - 0.00011 20.9 0.1 0.32 9.5 0.0 2.7 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.16 OAJ24646.1 - 0.00012 21.2 0.0 0.26 10.4 0.0 3.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 OAJ24646.1 - 0.00024 20.7 0.0 0.14 11.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF853 PF05872.7 OAJ24646.1 - 0.00034 19.0 1.7 0.19 10.0 0.0 2.7 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF853) TIP49 PF06068.8 OAJ24646.1 - 0.00041 19.1 0.5 0.071 11.8 0.0 3.0 3 0 0 3 3 3 1 TIP49 C-terminus ResIII PF04851.10 OAJ24646.1 - 0.00042 20.1 1.1 0.66 9.7 0.0 3.5 2 2 2 4 4 3 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 OAJ24646.1 - 0.00064 19.7 2.6 0.99 9.3 0.0 3.9 4 1 0 4 4 4 1 AAA domain Arch_ATPase PF01637.13 OAJ24646.1 - 0.00082 19.1 4.1 0.058 13.0 0.1 3.4 3 1 0 3 3 2 1 Archaeal ATPase NACHT PF05729.7 OAJ24646.1 - 0.0011 18.6 0.3 0.47 10.1 0.0 3.1 3 0 0 3 3 3 1 NACHT domain T2SE PF00437.15 OAJ24646.1 - 0.0011 17.8 0.0 0.025 13.4 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 OAJ24646.1 - 0.0016 18.1 0.0 0.66 9.6 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 OAJ24646.1 - 0.0022 17.4 0.0 1.6 8.1 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 OAJ24646.1 - 0.004 17.3 0.1 2.9 8.1 0.0 2.9 3 0 0 3 3 2 1 RNA helicase Torsin PF06309.6 OAJ24646.1 - 0.0052 16.6 0.0 0.039 13.8 0.0 2.1 2 0 0 2 2 2 1 Torsin SRP54 PF00448.17 OAJ24646.1 - 0.0073 15.7 0.1 2.2 7.6 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CENP-F_leu_zip PF10473.4 OAJ24646.1 - 0.0075 16.1 10.7 0.016 15.0 7.4 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2075 PF09848.4 OAJ24646.1 - 0.011 14.7 1.7 0.055 12.4 0.0 2.7 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) IncA PF04156.9 OAJ24646.1 - 0.014 14.9 6.8 0.033 13.7 4.7 1.6 1 0 0 1 1 1 0 IncA protein AAA_33 PF13671.1 OAJ24646.1 - 0.03 14.1 0.2 11 5.8 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.1 OAJ24646.1 - 0.034 13.5 2.8 8.3 5.7 0.0 3.5 3 1 0 4 4 3 0 AAA domain AAA_3 PF07726.6 OAJ24646.1 - 0.04 13.5 0.0 0.4 10.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.16 OAJ24646.1 - 0.049 12.9 0.1 0.049 12.9 0.0 3.4 2 1 0 2 2 1 0 UvrD/REP helicase N-terminal domain FadA PF09403.5 OAJ24646.1 - 0.052 13.5 3.5 0.14 12.1 2.4 1.7 1 0 0 1 1 1 0 Adhesion protein FadA PhoH PF02562.11 OAJ24646.1 - 0.071 12.3 0.1 7.1 5.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein UPF0079 PF02367.12 OAJ24646.1 - 0.12 12.0 0.0 13 5.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF4266 PF14086.1 OAJ24646.1 - 0.22 12.0 5.8 0.65 10.5 2.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) DUF87 PF01935.12 OAJ24646.1 - 0.36 10.5 5.2 4.3 7.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_23 PF13476.1 OAJ24646.1 - 1.6 9.0 12.3 1.9 8.8 0.0 3.4 2 1 0 2 2 1 0 AAA domain RasGAP PF00616.14 OAJ24647.1 - 4.4e-24 85.2 0.0 4.2e-23 82.0 0.0 2.0 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 OAJ24647.1 - 0.00051 19.8 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain She9_MDM33 PF05546.6 OAJ24652.1 - 4e-60 202.9 8.9 5.9e-60 202.3 6.2 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family TINF2_N PF14973.1 OAJ24652.1 - 0.022 14.9 0.7 2 8.5 0.0 2.2 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus DUF2524 PF10732.4 OAJ24652.1 - 1.7 8.7 9.2 0.29 11.3 1.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) Cauli_VI PF01693.11 OAJ24653.1 - 0.00044 20.2 0.0 0.0008 19.3 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin TMP_2 PF06791.8 OAJ24655.1 - 0.0072 15.9 0.0 0.0098 15.5 0.0 1.3 1 1 0 1 1 1 1 Prophage tail length tape measure protein Sipho_Gp157 PF05565.6 OAJ24655.1 - 0.029 13.9 0.6 0.036 13.6 0.4 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 Uso1_p115_C PF04871.8 OAJ24655.1 - 0.038 13.9 0.5 0.049 13.5 0.3 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2857 PF11198.3 OAJ24655.1 - 0.062 12.8 0.2 0.075 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) HHA PF05321.6 OAJ24655.1 - 0.11 12.6 0.5 16 5.7 0.0 2.2 2 0 0 2 2 2 0 Haemolysin expression modulating protein Methyltrn_RNA_2 PF04013.7 OAJ24655.1 - 0.11 11.9 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase SGL PF08450.7 OAJ24656.1 - 0.065 12.5 0.1 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region GDC-P PF02347.11 OAJ24657.1 - 1.4e-183 610.4 0.0 3.7e-171 569.5 0.0 2.8 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 OAJ24657.1 - 0.00019 20.7 0.0 0.00051 19.2 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase DUF1885 PF08968.5 OAJ24657.1 - 0.091 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) Pkinase PF00069.20 OAJ24659.1 - 4.4e-56 189.9 0.0 6.8e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ24659.1 - 1.9e-20 73.0 0.0 9.9e-20 70.6 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase TIP49 PF06068.8 OAJ24660.1 - 1.1e-172 574.2 0.2 1.3e-172 574.0 0.2 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 OAJ24660.1 - 4.1e-12 46.4 0.7 2.7e-09 37.3 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 OAJ24660.1 - 6.7e-12 44.9 0.8 9.4e-09 34.6 0.0 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 OAJ24660.1 - 3e-08 33.8 0.0 1.3e-07 31.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ24660.1 - 1.8e-07 31.3 0.1 0.0058 16.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain DnaB_C PF03796.10 OAJ24660.1 - 6.1e-06 25.3 0.2 1.1e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_5 PF07728.9 OAJ24660.1 - 7e-06 25.8 0.2 0.0033 17.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 OAJ24660.1 - 1.1e-05 24.6 0.7 0.00045 19.4 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 OAJ24660.1 - 4.8e-05 22.9 0.0 0.062 12.7 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 OAJ24660.1 - 7.6e-05 22.3 0.0 0.00029 20.5 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 OAJ24660.1 - 0.00014 21.3 0.2 0.00039 19.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ24660.1 - 0.00015 22.5 0.1 0.00088 20.0 0.0 2.2 2 2 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 OAJ24660.1 - 0.00037 19.9 0.0 0.00077 18.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 OAJ24660.1 - 0.0005 19.9 0.0 1.1 9.2 0.0 3.3 4 0 0 4 4 3 1 AAA domain Parvo_NS1 PF01057.12 OAJ24660.1 - 0.00057 18.8 0.0 0.00087 18.2 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.7 OAJ24660.1 - 0.0009 18.3 0.1 0.0018 17.4 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 OAJ24660.1 - 0.0019 17.8 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 OAJ24660.1 - 0.0021 18.3 0.3 0.0089 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAJ24660.1 - 0.0072 16.1 0.0 0.021 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAJ24660.1 - 0.0073 15.9 0.1 0.012 15.1 0.1 1.4 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 OAJ24660.1 - 0.01 14.8 0.2 0.026 13.5 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 OAJ24660.1 - 0.014 14.6 0.1 0.034 13.3 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 OAJ24660.1 - 0.014 14.9 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 OAJ24660.1 - 0.016 15.5 0.1 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 OAJ24660.1 - 0.018 14.0 0.6 0.74 8.6 0.1 2.2 2 0 0 2 2 2 0 PIF1-like helicase ResIII PF04851.10 OAJ24660.1 - 0.024 14.4 0.2 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 OAJ24660.1 - 0.025 14.5 0.5 0.053 13.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_2 PF07724.9 OAJ24660.1 - 0.029 14.2 0.1 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 OAJ24660.1 - 0.04 13.9 0.0 0.53 10.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain T2SE PF00437.15 OAJ24660.1 - 0.045 12.6 1.7 0.12 11.1 0.1 2.2 1 1 1 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.17 OAJ24660.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 OAJ24660.1 - 0.067 12.7 0.5 1.1 8.8 0.0 2.6 3 0 0 3 3 2 0 P-loop containing region of AAA domain APS_kinase PF01583.15 OAJ24660.1 - 0.081 12.5 0.2 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase NTPase_1 PF03266.10 OAJ24660.1 - 0.1 12.2 1.9 0.38 10.4 0.3 2.5 2 1 0 2 2 2 0 NTPase Sipho_tail PF05709.6 OAJ24660.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Phage tail protein CM_2 PF01817.16 OAJ24661.1 - 0.085 12.9 0.0 11 6.1 0.0 2.5 2 1 0 2 2 2 0 Chorismate mutase type II CDP-OH_P_transf PF01066.16 OAJ24662.1 - 1.9e-11 44.1 1.4 4.2e-11 43.0 1.0 1.6 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Tetraspannin PF00335.15 OAJ24663.1 - 1.4e-05 24.4 6.1 2e-05 24.0 1.2 2.1 1 1 1 2 2 2 1 Tetraspanin family Shisa PF13908.1 OAJ24663.1 - 0.002 18.3 0.0 0.0062 16.7 0.0 1.8 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator COX15-CtaA PF02628.10 OAJ24663.1 - 0.04 12.7 2.7 0.062 12.1 0.9 1.8 2 0 0 2 2 2 0 Cytochrome oxidase assembly protein DsbB PF02600.11 OAJ24663.1 - 0.052 13.3 5.7 0.033 13.9 1.7 1.9 2 0 0 2 2 2 0 Disulfide bond formation protein DsbB Claudin_2 PF13903.1 OAJ24663.1 - 0.057 13.1 2.5 0.37 10.4 0.2 2.4 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2207 PF09972.4 OAJ24663.1 - 0.098 11.2 1.1 1.2 7.6 0.0 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF3040 PF11239.3 OAJ24663.1 - 1.8 8.6 6.7 9.6 6.3 1.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) zf-HIT PF04438.11 OAJ24664.1 - 5.6e-09 35.4 10.3 7.9e-09 35.0 7.1 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.19 OAJ24664.1 - 0.14 12.1 4.8 0.22 11.4 3.3 1.3 1 0 0 1 1 1 0 B-box zinc finger RNA_POL_M_15KD PF02150.11 OAJ24665.1 - 1.9e-12 46.6 4.1 1.9e-12 46.6 2.8 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 OAJ24665.1 - 1.5e-11 43.6 13.6 8.6e-11 41.2 2.8 3.0 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) GFA PF04828.9 OAJ24665.1 - 0.0012 18.7 6.8 0.033 14.1 2.4 2.4 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.1 OAJ24665.1 - 0.0012 19.0 4.5 0.051 13.8 0.9 2.2 2 0 0 2 2 2 1 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 OAJ24665.1 - 0.03 14.2 10.6 2.3 8.2 0.1 3.9 4 0 0 4 4 4 0 Zinc ribbon domain Elf1 PF05129.8 OAJ24665.1 - 0.036 13.7 4.5 2.1 8.0 0.3 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.1 OAJ24665.1 - 0.14 11.4 0.1 0.14 11.4 0.1 3.4 4 0 0 4 4 3 0 zinc-ribbon domain zf-ISL3 PF14690.1 OAJ24665.1 - 0.19 11.7 2.2 1.5 8.9 0.0 2.8 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DZR PF12773.2 OAJ24665.1 - 0.21 11.4 11.9 0.3 10.9 0.3 2.8 2 1 1 3 3 3 0 Double zinc ribbon zf-C2H2_4 PF13894.1 OAJ24665.1 - 0.31 11.4 8.5 1.9 9.0 0.2 3.5 4 0 0 4 4 3 0 C2H2-type zinc finger Rubredoxin PF00301.15 OAJ24665.1 - 1 9.3 8.0 6.7 6.6 0.0 3.7 4 0 0 4 4 4 0 Rubredoxin TF_Zn_Ribbon PF08271.7 OAJ24665.1 - 1.3 8.3 12.4 0.14 11.5 2.1 3.2 3 1 1 4 4 4 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 OAJ24665.1 - 1.7 8.4 12.1 8 6.3 3.1 2.9 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF3268 PF11672.3 OAJ24665.1 - 2.5 8.2 6.7 9.7 6.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) OrfB_Zn_ribbon PF07282.6 OAJ24665.1 - 3.1 7.5 6.0 6.3 6.5 0.3 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain C1_4 PF07975.7 OAJ24665.1 - 3.3 7.8 15.6 0.63 10.0 1.0 2.9 2 1 1 3 3 3 0 TFIIH C1-like domain DUF3795 PF12675.2 OAJ24665.1 - 3.5 7.8 7.3 6 7.1 2.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3795) HNH_5 PF14279.1 OAJ24665.1 - 3.8 7.5 10.8 11 6.0 1.6 3.2 2 2 0 2 2 2 0 HNH endonuclease zf-UBR PF02207.15 OAJ24665.1 - 5.1 6.9 11.5 4.9 6.9 0.6 3.1 3 1 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) HypA PF01155.14 OAJ24665.1 - 9.6 5.9 8.1 0.75 9.4 0.5 2.4 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family Ribosomal_L31e PF01198.14 OAJ24666.1 - 6.3e-33 112.3 3.0 1.1e-32 111.5 2.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L31e Arginosuc_synth PF00764.14 OAJ24667.1 - 1.3e-155 518.2 0.0 1.6e-155 517.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 OAJ24667.1 - 0.00025 20.3 0.0 0.00039 19.7 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 OAJ24667.1 - 0.002 17.6 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase LolA PF03548.10 OAJ24667.1 - 0.028 14.0 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA tRNA_Me_trans PF03054.11 OAJ24667.1 - 0.07 11.6 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase DUF3535 PF12054.3 OAJ24668.1 - 1.2e-111 373.4 0.0 2.3e-110 369.2 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 OAJ24668.1 - 4.4e-71 239.1 0.0 6.6e-71 238.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 OAJ24668.1 - 5.7e-13 47.7 28.1 0.031 14.3 0.0 11.2 13 0 0 13 13 13 3 HEAT repeat Helicase_C PF00271.26 OAJ24668.1 - 6.5e-12 45.1 0.0 1.6e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 OAJ24668.1 - 0.0039 17.4 30.2 0.0048 17.1 0.2 8.9 9 2 1 10 10 10 1 HEAT repeats HEAT_EZ PF13513.1 OAJ24668.1 - 0.0044 17.4 33.5 8 7.1 0.1 11.5 11 1 1 12 12 12 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 OAJ24668.1 - 0.022 15.1 0.0 0.26 11.7 0.0 2.4 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HDA2-3 PF11496.3 OAJ24668.1 - 0.078 11.7 0.0 0.19 10.4 0.0 1.5 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 RIX1 PF08167.7 OAJ24668.1 - 0.096 12.3 0.1 4.5 6.9 0.0 2.7 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Smr PF01713.16 OAJ24669.1 - 4.2e-10 39.6 0.0 3.9e-09 36.5 0.0 2.7 2 1 0 2 2 2 1 Smr domain DNA_pol_phi PF04931.8 OAJ24669.1 - 8.9 3.9 5.1 14 3.3 3.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Stonin2_N PF12016.3 OAJ24670.1 - 0.073 12.1 2.2 0.081 12.0 1.5 1.0 1 0 0 1 1 1 0 Stonin 2 ATP13 PF12921.2 OAJ24674.1 - 0.075 12.3 0.0 0.35 10.2 0.0 2.0 1 1 1 2 2 2 0 Mitochondrial ATPase expression Ribosomal_L14e PF01929.12 OAJ24675.1 - 8.9e-25 86.8 0.7 1.4e-24 86.2 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 OAJ24675.1 - 0.026 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 KOW motif Ribosomal_L44 PF00935.14 OAJ24676.1 - 2.1e-35 120.5 12.3 3.1e-35 120.0 8.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Dynamin_N PF00350.18 OAJ24680.1 - 1.4e-16 60.8 0.0 3.5e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 OAJ24680.1 - 9.5e-11 41.6 0.1 4.6e-10 39.4 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAJ24680.1 - 4.5e-08 32.7 0.4 8e-07 28.6 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 OAJ24680.1 - 0.00048 20.5 0.0 0.092 13.2 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein IIGP PF05049.8 OAJ24680.1 - 0.0033 16.2 0.2 0.014 14.2 0.0 1.9 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 OAJ24680.1 - 0.0077 15.7 0.0 0.02 14.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain FeoB_N PF02421.13 OAJ24680.1 - 0.1 11.8 0.2 7.1 5.8 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.4 OAJ24680.1 - 0.15 11.5 0.1 7.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NPV_P10 PF05531.7 OAJ24680.1 - 0.24 11.6 6.9 23 5.3 0.1 4.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.20 OAJ24681.1 - 1.4e-41 142.3 0.0 6.1e-39 133.7 0.0 3.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ24681.1 - 3.4e-23 82.0 0.0 1.7e-19 69.9 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 OAJ24681.1 - 0.0038 16.2 0.0 0.36 9.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like PBP1_TM PF14812.1 OAJ24681.1 - 7.7 6.9 15.8 13 6.1 0.0 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDE_Tnp_4 PF13359.1 OAJ24682.1 - 4e-28 97.9 0.0 5.9e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ24682.1 - 5e-07 29.3 0.0 0.00022 20.7 0.0 2.2 2 0 0 2 2 2 2 Plant transposon protein Myb_DNA-bind_3 PF12776.2 OAJ24683.1 - 1.6e-13 51.1 0.6 2.6e-13 50.4 0.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ24683.1 - 0.0037 17.3 2.5 0.011 15.8 1.7 1.9 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Zn_clus PF00172.13 OAJ24684.1 - 3.9e-06 26.6 9.9 8.1e-06 25.6 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.21 OAJ24685.1 - 8.3e-38 129.5 0.0 9.4e-38 129.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Glyco_hydro_45 PF02015.11 OAJ24687.1 - 5.4e-49 166.9 5.2 7.1e-49 166.6 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Yae1_N PF09811.4 OAJ24688.1 - 1.6e-05 24.3 8.9 2.7e-05 23.6 6.2 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Lipase_3 PF01764.20 OAJ24689.1 - 4.2e-23 81.5 0.0 5.5e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 OAJ24689.1 - 0.011 15.4 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAJ24689.1 - 0.018 14.6 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_9 PF10081.4 OAJ24689.1 - 0.03 13.0 0.1 5.3 5.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta-hydrolase family Aldo_ket_red PF00248.16 OAJ24692.1 - 3.5e-52 176.9 0.0 4.2e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DSBA PF01323.15 OAJ24694.1 - 2.9e-25 88.9 0.0 3.7e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain RVT_1 PF00078.22 OAJ24695.1 - 3.8e-16 59.1 0.0 8.6e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ24695.1 - 1.1e-13 51.3 0.0 2.8e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain DUF2508 PF10704.4 OAJ24696.1 - 0.34 11.1 2.0 0.46 10.6 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) PAZ PF02170.17 OAJ24700.1 - 3.8e-08 32.7 0.0 5.6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 PAZ domain DUF1797 PF08796.5 OAJ24700.1 - 0.031 14.1 0.1 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) DUF1517 PF07466.6 OAJ24700.1 - 0.091 11.7 1.7 0.12 11.3 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF2763 PF10961.3 OAJ24700.1 - 9.1 6.7 13.5 16 5.9 9.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) Peptidase_M13_N PF05649.8 OAJ24704.1 - 1.4e-06 27.6 0.0 1.7e-06 27.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 DUF566 PF04484.7 OAJ24707.1 - 0.052 13.0 6.3 0.056 12.9 4.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) PAT1 PF09770.4 OAJ24707.1 - 5.6 5.0 7.1 5.9 4.9 4.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PCI PF01399.22 OAJ24708.1 - 0.0085 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 PCI domain Sec1 PF00995.18 OAJ24709.1 - 1.3e-45 156.0 0.0 1.5e-45 155.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_hydro_63 PF03200.11 OAJ24711.1 - 2.3e-09 35.6 1.7 8.7e-08 30.5 0.2 3.3 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase Methyltransf_16 PF10294.4 OAJ24711.1 - 2.3e-08 33.7 0.0 0.0018 17.7 0.0 2.4 2 0 0 2 2 2 2 Putative methyltransferase UDPGT PF00201.13 OAJ24711.1 - 0.73 8.3 0.0 1.1 7.6 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase ubiquitin PF00240.18 OAJ24713.1 - 9.1e-19 66.6 0.4 1.4e-18 66.0 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 OAJ24713.1 - 1.2e-13 50.4 5.7 2.3e-06 27.2 0.2 3.2 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.6 OAJ24713.1 - 2.3e-12 46.1 14.5 4.5e-12 45.2 10.0 1.5 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.3 OAJ24713.1 - 1.1e-07 31.4 0.5 1.9e-07 30.6 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 OAJ24713.1 - 0.00071 19.4 0.1 0.0015 18.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 OAJ24713.1 - 0.011 15.2 0.0 0.28 10.7 0.0 2.7 2 0 0 2 2 2 0 UBA-like domain DUF2407 PF10302.4 OAJ24713.1 - 0.049 13.8 0.0 0.088 13.0 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CSTF2_hinge PF14327.1 OAJ24713.1 - 0.2 11.7 6.4 1.7 8.7 4.3 2.3 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 RAP1 PF07218.6 OAJ24713.1 - 1.5 6.8 5.2 2 6.4 3.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2992 PF11208.3 OAJ24714.1 - 0.077 12.8 0.7 0.15 11.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Ribosomal_L23 PF00276.15 OAJ24715.1 - 2.7e-08 33.6 0.0 1.7e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L23 MULE PF10551.4 OAJ24716.1 - 1.1e-09 38.3 0.1 1.1e-08 35.1 0.0 2.7 2 1 1 3 3 3 1 MULE transposase domain SWIM PF04434.12 OAJ24716.1 - 0.015 14.7 0.1 0.043 13.3 0.1 1.8 1 0 0 1 1 1 0 SWIM zinc finger DUF987 PF06174.6 OAJ24717.1 - 0.14 11.7 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF987) PNP_UDP_1 PF01048.15 OAJ24718.1 - 3.6e-34 117.7 0.7 4.2e-34 117.5 0.5 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily p450 PF00067.17 OAJ24719.1 - 1.2e-50 172.4 0.0 1.5e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fer2_BFD PF04324.10 OAJ24720.1 - 0.19 11.7 0.3 0.41 10.7 0.2 1.6 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain Pkinase PF00069.20 OAJ24721.1 - 4.9e-58 196.3 0.0 4.8e-57 193.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ24721.1 - 1.2e-33 116.3 0.0 1.9e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ24721.1 - 5.5e-05 23.0 0.0 5.5e-05 23.0 0.0 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ24721.1 - 0.0016 17.4 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF3584 PF12128.3 OAJ24721.1 - 0.01 13.2 11.5 0.017 12.5 8.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Ubie_methyltran PF01209.13 OAJ24731.1 - 8.2e-71 237.8 0.0 1.3e-37 129.1 0.0 2.2 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 OAJ24731.1 - 5.3e-11 42.8 0.0 6.8e-10 39.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ24731.1 - 2e-10 41.0 0.0 4.1e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ24731.1 - 1.8e-09 37.3 0.0 2.2e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ24731.1 - 7.8e-07 28.9 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ24731.1 - 1e-06 29.3 0.0 2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ24731.1 - 1.7e-06 28.0 0.0 4.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ24731.1 - 1.4e-05 25.4 0.0 2.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 OAJ24731.1 - 0.0081 15.8 0.0 0.026 14.1 0.0 1.7 2 0 0 2 2 2 1 Hypothetical methyltransferase MTS PF05175.9 OAJ24731.1 - 0.059 12.7 0.0 0.44 9.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Glyco_transf_90 PF05686.7 OAJ24731.1 - 0.11 11.2 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 90 Cullin PF00888.17 OAJ24732.1 - 1.9e-176 588.0 3.4 2.6e-176 587.6 2.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 OAJ24732.1 - 1.2e-27 95.4 1.4 2.7e-27 94.3 0.9 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_27 PF13463.1 OAJ24732.1 - 0.0024 18.1 0.1 6.9 7.0 0.0 3.3 4 0 0 4 4 4 2 Winged helix DNA-binding domain Penicillinase_R PF03965.11 OAJ24732.1 - 0.023 14.8 2.1 18 5.4 0.0 3.9 4 0 0 4 4 4 0 Penicillinase repressor GPI-anchored PF10342.4 OAJ24733.1 - 5.8e-10 39.5 0.1 5.8e-10 39.5 0.1 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF952 PF06108.7 OAJ24734.1 - 8.4e-14 51.2 0.0 1.2e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Glycos_transf_4 PF00953.16 OAJ24735.1 - 4.7e-32 110.9 7.2 9.5e-32 109.9 5.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 4 Mob1_phocein PF03637.12 OAJ24736.1 - 1.1e-55 187.9 0.7 1.4e-55 187.6 0.5 1.1 1 0 0 1 1 1 1 Mob1/phocein family CAP59_mtransfer PF11735.3 OAJ24737.1 - 6.3e-67 225.3 0.0 1.3e-63 214.4 0.0 2.2 2 0 0 2 2 2 2 Cryptococcal mannosyltransferase 1 Dicty_REP PF05086.7 OAJ24737.1 - 0.54 7.9 5.6 0.74 7.4 3.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BUD22 PF09073.5 OAJ24737.1 - 1.2 8.1 10.4 2.2 7.2 7.2 1.3 1 0 0 1 1 1 0 BUD22 MFS_1 PF07690.11 OAJ24739.1 - 1.7e-25 89.4 35.9 6.4e-17 61.2 9.1 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Choline_transpo PF04515.7 OAJ24740.1 - 6.1e-86 288.1 23.6 6.1e-86 288.1 16.4 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.8 OAJ24740.1 - 0.028 14.4 0.9 0.083 12.9 0.6 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1418 PF07214.7 OAJ24740.1 - 0.19 11.3 1.3 0.69 9.5 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) Fasciclin PF02469.17 OAJ24741.1 - 5e-28 97.6 8.1 6.3e-21 74.7 2.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Ub-RnfH PF03658.9 OAJ24741.1 - 0.054 13.3 0.1 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RnfH family Ubiquitin DnaJ PF00226.26 OAJ24742.1 - 2.2e-09 36.8 0.5 6.7e-09 35.3 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain Abhydrolase_5 PF12695.2 OAJ24743.1 - 0.00026 20.7 0.0 0.00067 19.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ24743.1 - 0.0044 16.2 0.0 0.0099 15.1 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Bestrophin PF01062.16 OAJ24744.1 - 3.1e-24 85.4 0.4 3.2e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel tRNA-synt_1c PF00749.16 OAJ24745.1 - 7.4e-104 346.7 0.0 1.4e-103 345.9 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 OAJ24745.1 - 2.5e-36 124.9 0.2 4.1e-36 124.2 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 OAJ24745.1 - 2.5e-05 24.6 0.1 7.8e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DSS1_SEM1 PF05160.8 OAJ24745.1 - 0.04 13.6 0.5 0.11 12.3 0.3 1.7 1 0 0 1 1 1 0 DSS1/SEM1 family GST_C_2 PF13410.1 OAJ24745.1 - 0.042 13.7 1.3 0.078 12.8 0.2 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain CS PF04969.11 OAJ24746.1 - 2.2e-07 31.3 0.0 1.6e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 CS domain Isochorismatase PF00857.15 OAJ24747.1 - 1.6e-22 80.2 0.1 5.4e-14 52.4 0.0 2.4 2 0 0 2 2 2 2 Isochorismatase family zf-ZPR1 PF03367.8 OAJ24748.1 - 2.2e-95 316.2 0.3 4e-46 156.1 0.0 3.2 2 1 1 3 3 3 3 ZPR1 zinc-finger domain HypA PF01155.14 OAJ24748.1 - 0.014 15.1 2.9 1.2 8.8 0.2 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 OAJ24748.1 - 0.13 11.5 6.4 5.6 6.3 0.0 3.6 2 2 1 3 3 3 0 zinc-ribbon domain DZR PF12773.2 OAJ24748.1 - 2.4 8.0 11.8 21 5.0 0.2 4.2 3 2 1 4 4 4 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 OAJ24748.1 - 5.3 6.6 12.3 2.1 7.9 0.7 4.0 5 0 0 5 5 5 0 zinc-ribbon domain Fungal_trans PF04082.13 OAJ24749.1 - 5.3e-28 97.6 0.0 9.6e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 OAJ24749.1 - 1.2e-08 34.7 15.2 1.3e-05 25.2 0.5 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ24749.1 - 3.2e-07 30.2 10.3 0.00027 21.0 0.3 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ24749.1 - 0.054 13.8 0.1 0.054 13.8 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double domain HSF_DNA-bind PF00447.12 OAJ24750.1 - 6.7e-20 71.2 0.0 1e-18 67.4 0.0 2.2 1 1 0 1 1 1 1 HSF-type DNA-binding Pro_isomerase PF00160.16 OAJ24751.1 - 1.3e-43 148.9 0.1 1.4e-43 148.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F-box-like PF12937.2 OAJ24752.1 - 3.7e-06 26.5 0.1 7.8e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like BSP_II PF05432.6 OAJ24752.1 - 0.0016 17.8 0.2 0.0016 17.8 0.2 3.2 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) F-box PF00646.28 OAJ24752.1 - 0.017 14.7 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 F-box domain Nucleo_P87 PF07267.6 OAJ24752.1 - 0.32 9.6 0.3 0.52 8.9 0.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PI-PLC-X PF00388.14 OAJ24753.1 - 2.1e-45 153.7 0.0 3.4e-45 153.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 OAJ24753.1 - 4.5e-32 110.4 0.0 9.1e-32 109.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 OAJ24753.1 - 0.96 9.3 3.3 4 7.3 0.9 2.7 2 1 0 2 2 2 0 C2 domain UPF0147 PF03685.8 OAJ24757.1 - 0.072 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) F-box-like PF12937.2 OAJ24757.1 - 0.096 12.4 0.2 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 F-box-like DUF2613 PF11021.3 OAJ24758.1 - 0.031 14.0 0.8 0.11 12.2 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Na_Ca_ex PF01699.19 OAJ24763.1 - 6.1e-19 68.0 23.8 8.3e-13 48.1 4.5 3.0 3 1 0 3 3 3 2 Sodium/calcium exchanger protein HUN PF08729.5 OAJ24764.1 - 5.5e-10 38.9 0.1 5.5e-10 38.9 0.1 2.4 2 0 0 2 2 2 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 OAJ24764.1 - 0.0089 15.7 0.1 0.0089 15.7 0.0 3.6 4 0 0 4 4 4 1 Ubinuclein conserved middle domain Nop14 PF04147.7 OAJ24764.1 - 7.2 4.3 15.8 0.19 9.6 4.8 2.1 2 0 0 2 2 2 0 Nop14-like family Aldo_ket_red PF00248.16 OAJ24766.1 - 3.7e-53 180.2 0.0 4.4e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Nitr_red_assoc PF09655.5 OAJ24767.1 - 0.088 13.1 1.1 0.12 12.6 0.1 1.6 2 0 0 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Unstab_antitox PF09720.5 OAJ24767.1 - 2.6 7.7 5.6 1.2 8.8 2.3 1.6 2 0 0 2 2 2 0 Putative addiction module component DEC-1_N PF04625.8 OAJ24769.1 - 0.057 12.0 0.9 0.069 11.8 0.7 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RNase_PH_C PF03725.10 OAJ24769.1 - 0.092 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 H_lectin PF09458.5 OAJ24770.1 - 2.7e-06 26.9 0.0 0.013 15.1 0.0 2.7 2 0 0 2 2 2 2 H-type lectin domain tRNA-synt_1c_C PF03950.13 OAJ24773.1 - 0.021 14.5 0.1 0.027 14.1 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain DUF447 PF04289.7 OAJ24773.1 - 0.099 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Sigma54_CBD PF04963.8 OAJ24775.1 - 0.0019 17.6 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain T2SK PF03934.8 OAJ24775.1 - 0.028 13.6 0.1 0.031 13.4 0.1 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K V-SNARE PF05008.10 OAJ24775.1 - 0.13 12.4 0.4 2.7 8.2 0.1 2.1 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus adh_short PF00106.20 OAJ24780.1 - 1.5e-28 99.7 1.7 1.5e-28 99.7 1.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ24780.1 - 3.9e-27 95.5 0.3 5e-27 95.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ24780.1 - 3.3e-12 46.4 2.6 3.3e-12 46.4 1.8 2.4 1 1 1 2 2 2 1 KR domain DUF3437 PF11919.3 OAJ24781.1 - 9.1e-20 70.1 0.0 4.4e-19 67.9 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.1 OAJ24781.1 - 4.7e-05 23.5 0.1 0.072 13.3 0.0 4.2 2 1 1 3 3 3 2 HEAT repeats DUF2435 PF10363.4 OAJ24781.1 - 0.037 13.9 0.1 0.096 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) NAPRTase PF04095.11 OAJ24782.1 - 2.7e-41 141.4 0.2 1.5e-16 60.4 0.0 3.3 3 0 0 3 3 3 3 Nicotinate phosphoribosyltransferase (NAPRTase) family Exo_endo_phos PF03372.18 OAJ24783.1 - 1.8e-24 87.0 2.0 4e-10 40.0 0.0 3.3 3 0 0 3 3 3 3 Endonuclease/Exonuclease/phosphatase family Robl_LC7 PF03259.12 OAJ24783.1 - 2.2 7.8 5.1 1.8 8.1 1.4 2.4 2 0 0 2 2 2 0 Roadblock/LC7 domain WD40 PF00400.27 OAJ24784.1 - 4.7e-12 45.2 2.7 5.3e-06 26.1 0.0 3.1 3 1 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 OAJ24784.1 - 0.058 12.1 0.1 0.12 11.0 0.0 1.5 2 1 0 2 2 2 0 Nup133 N terminal like COesterase PF00135.23 OAJ24785.1 - 4.5e-109 365.5 0.0 6.5e-109 365.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ24785.1 - 3.5e-10 39.8 0.2 1.3e-09 37.9 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF4131 PF13567.1 OAJ24787.1 - 0.053 12.9 1.1 0.16 11.3 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) UPF0182 PF03699.8 OAJ24787.1 - 8.2 4.2 12.0 0.49 8.2 3.3 2.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0182) Methyltransf_11 PF08241.7 OAJ24788.1 - 6.9e-07 29.6 0.1 8.6e-06 26.1 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ24788.1 - 0.00011 21.8 0.0 0.00049 19.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ24788.1 - 0.00056 20.2 0.0 0.0084 16.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ24788.1 - 0.002 18.5 0.0 0.0053 17.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ24788.1 - 0.0021 18.6 0.2 0.0075 16.8 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ24788.1 - 0.0028 17.3 0.0 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ24788.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF3663 PF12404.3 OAJ24788.1 - 0.071 12.8 1.6 0.64 9.8 0.4 2.2 2 0 0 2 2 2 0 Peptidase DUF1676 PF07898.8 OAJ24789.1 - 0.018 15.3 0.8 0.058 13.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Mt_ATP-synt_D PF05873.7 OAJ24790.1 - 6.7e-10 38.8 0.5 8.4e-10 38.5 0.3 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) MiaE_2 PF13794.1 OAJ24790.1 - 0.013 15.0 0.2 0.022 14.2 0.1 1.4 1 1 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like DUF1366 PF07104.6 OAJ24790.1 - 0.015 14.9 2.8 0.028 14.0 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) DUF2408 PF10303.4 OAJ24790.1 - 0.05 13.7 0.8 0.087 12.9 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) HsbA PF12296.3 OAJ24790.1 - 0.076 12.8 1.9 0.16 11.8 0.4 1.9 1 1 1 2 2 2 0 Hydrophobic surface binding protein A Cauli_AT PF03233.8 OAJ24790.1 - 0.093 12.4 1.3 0.16 11.6 0.9 1.4 1 0 0 1 1 1 0 Aphid transmission protein MbeB_N PF04837.7 OAJ24790.1 - 0.26 11.4 3.3 0.17 12.0 0.6 1.9 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Pribosyltran PF00156.22 OAJ24791.1 - 3.1e-10 39.8 0.0 5.3e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CDC27 PF09507.5 OAJ24792.1 - 0.75 8.9 5.9 0.55 9.4 2.5 1.9 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DUF3628 PF12300.3 OAJ24794.1 - 0.0032 17.5 2.2 0.14 12.1 3.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3628) Lant_dehyd_C PF04738.8 OAJ24794.1 - 0.024 12.8 0.1 0.031 12.5 0.1 1.1 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus DUF4088 PF13317.1 OAJ24794.1 - 0.049 12.9 0.6 0.063 12.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) DUF615 PF04751.9 OAJ24794.1 - 0.75 9.4 5.2 0.4 10.3 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF615) Fe-ADH PF00465.14 OAJ24795.1 - 6.1e-68 229.1 0.0 7.9e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 OAJ24795.1 - 4.9e-16 58.7 0.2 1.1e-14 54.4 0.2 2.3 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 OAJ24795.1 - 0.005 15.8 0.2 0.31 9.9 0.0 2.5 3 0 0 3 3 3 2 3-dehydroquinate synthase SPT16 PF08644.6 OAJ24796.1 - 6.5e-51 172.1 0.1 2.2e-50 170.4 0.0 2.0 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 OAJ24796.1 - 4e-40 137.0 0.8 1.1e-39 135.5 0.6 1.8 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 OAJ24796.1 - 1.4e-22 80.2 0.0 2.8e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 OAJ24796.1 - 1.8e-20 72.6 1.2 5.1e-20 71.2 0.0 2.4 4 0 0 4 4 4 1 Histone chaperone Rttp106-like Cys_Met_Meta_PP PF01053.15 OAJ24797.1 - 6.2e-119 396.7 0.0 2.2e-118 394.9 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 OAJ24797.1 - 2.7e-16 59.3 1.9 1.3e-15 57.2 1.1 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 OAJ24797.1 - 6.4e-05 23.0 0.3 0.00079 19.5 0.1 2.9 1 1 1 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 OAJ24797.1 - 0.0063 15.7 0.3 0.013 14.7 0.2 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Aminotran_1_2 PF00155.16 OAJ24797.1 - 0.066 12.1 0.5 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class I and II HEAT PF02985.17 OAJ24798.1 - 6.3e-11 41.4 16.0 0.027 14.5 0.0 9.8 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 OAJ24798.1 - 3.2e-10 40.1 16.1 0.0018 18.5 0.0 6.3 2 2 3 5 5 5 4 HEAT repeats Adaptin_N PF01602.15 OAJ24798.1 - 0.0014 17.0 3.3 0.079 11.2 0.0 2.8 3 0 0 3 3 3 2 Adaptin N terminal region DUF4042 PF13251.1 OAJ24798.1 - 0.73 9.2 0.5 24 4.3 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4042) Atg8 PF02991.11 OAJ24799.1 - 3.9e-52 174.5 0.2 4.6e-52 174.3 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 OAJ24799.1 - 5.2e-07 29.7 0.0 6.5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Macro PF01661.16 OAJ24806.1 - 1.3e-41 141.2 0.1 1.9e-41 140.6 0.1 1.2 1 0 0 1 1 1 1 Macro domain Aminotran_3 PF00202.16 OAJ24807.1 - 5.8e-105 350.8 0.0 9.6e-105 350.1 0.0 1.3 2 0 0 2 2 2 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 OAJ24807.1 - 0.0075 15.4 0.0 0.036 13.2 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase ABC_membrane_2 PF06472.10 OAJ24808.1 - 3.6e-101 337.9 4.2 4.7e-101 337.6 2.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 OAJ24808.1 - 5.2e-20 72.1 0.0 1.7e-19 70.4 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 OAJ24808.1 - 0.00022 21.3 0.1 0.00057 19.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 OAJ24808.1 - 0.014 14.6 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 OAJ24808.1 - 0.016 15.2 0.0 0.055 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 OAJ24808.1 - 0.022 15.0 3.3 0.16 12.2 2.3 2.2 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 OAJ24808.1 - 0.028 13.8 0.0 1.2 8.6 0.0 2.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_29 PF13555.1 OAJ24808.1 - 0.043 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 OAJ24808.1 - 0.047 12.8 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 OMPdecase PF00215.19 OAJ24809.1 - 3.1e-74 249.1 0.1 4.1e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Elf1 PF05129.8 OAJ24810.1 - 4.5e-25 87.1 2.3 5.3e-25 86.9 1.6 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.1 OAJ24810.1 - 0.04 14.2 2.7 0.057 13.7 1.8 1.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar Acetyltransf_1 PF00583.19 OAJ24811.1 - 3.9e-11 42.8 0.0 6.5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ24811.1 - 3.6e-05 23.8 0.1 8.1e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ24811.1 - 5e-05 22.9 0.0 8.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 OAJ24811.1 - 0.0087 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAJ24811.1 - 0.014 15.4 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain VPS9 PF02204.13 OAJ24813.1 - 4.5e-31 106.9 0.0 8.5e-31 106.0 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PUA PF01472.15 OAJ24814.1 - 3.1e-15 55.6 0.0 4.8e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 PUA domain MgtE PF01769.11 OAJ24815.1 - 2.7e-20 73.0 34.8 6.8e-09 36.1 0.3 5.3 6 0 0 6 6 6 4 Divalent cation transporter DUF4109 PF13397.1 OAJ24818.1 - 0.023 15.0 0.3 0.05 13.9 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4109) HTH_28 PF13518.1 OAJ24819.1 - 0.0026 17.7 0.5 0.014 15.3 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 OAJ24819.1 - 0.015 15.2 0.0 0.054 13.4 0.0 2.0 1 0 0 1 1 1 0 Transposase HTH_23 PF13384.1 OAJ24819.1 - 0.015 14.8 0.1 0.15 11.7 0.0 2.7 3 0 0 3 3 3 0 Homeodomain-like domain MULE PF10551.4 OAJ24820.1 - 3.5e-19 68.7 0.0 7.5e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ24820.1 - 4.4e-10 38.6 0.0 6e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family zf-C2H2 PF00096.21 OAJ24822.1 - 1.1e-06 28.6 2.2 0.0067 16.7 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ24822.1 - 0.0013 18.9 2.2 0.12 12.7 0.0 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger Daxx PF03344.10 OAJ24822.1 - 0.0017 16.9 6.9 0.0017 16.9 4.8 3.6 4 0 0 4 4 4 1 Daxx Family eIF-3c_N PF05470.7 OAJ24822.1 - 1.7 6.6 2.4 3.1 5.7 1.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RRN3 PF05327.6 OAJ24822.1 - 2 6.4 5.6 3.5 5.6 3.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.7 OAJ24822.1 - 2.1 6.1 23.6 0.019 12.9 10.6 1.7 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.9 OAJ24822.1 - 8.7 4.2 22.0 0.059 11.3 7.7 2.1 2 0 0 2 2 2 0 CDC45-like protein SnoaL_2 PF12680.2 OAJ24823.1 - 0.00019 21.7 0.2 0.007 16.7 0.0 2.7 2 1 0 2 2 2 1 SnoaL-like domain BcrAD_BadFG PF01869.15 OAJ24824.1 - 8.4e-07 28.5 0.1 0.0045 16.3 0.1 2.3 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Voldacs PF03517.8 OAJ24824.1 - 1.1 9.1 6.1 4.1 7.2 1.2 2.6 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling RXT2_N PF08595.6 OAJ24824.1 - 2 8.1 6.8 0.27 11.0 1.5 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal TFIIS_C PF01096.13 OAJ24825.1 - 1.2e-06 28.0 6.6 1.4e-06 27.8 0.0 3.3 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 OAJ24825.1 - 0.018 14.7 0.3 0.018 14.7 0.2 1.7 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit OrfB_Zn_ribbon PF07282.6 OAJ24825.1 - 0.039 13.5 0.1 0.07 12.7 0.1 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DZR PF12773.2 OAJ24825.1 - 0.039 13.7 0.2 0.088 12.6 0.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.17 OAJ24825.1 - 0.048 13.3 0.2 0.048 13.3 0.1 1.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) IBR PF01485.16 OAJ24825.1 - 0.072 12.9 0.3 3 7.7 0.1 2.2 2 0 0 2 2 2 0 IBR domain Zn_ribbon_recom PF13408.1 OAJ24825.1 - 0.08 13.2 0.5 2.1 8.6 0.2 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-NADH-PPase PF09297.6 OAJ24825.1 - 0.63 9.6 0.2 0.63 9.6 0.1 2.1 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain DUF678 PF05077.7 OAJ24825.1 - 0.72 9.8 3.3 11 6.0 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF678) ERG2_Sigma1R PF04622.7 OAJ24826.1 - 2.3e-83 278.7 0.0 2.9e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein MAGE_N PF12440.3 OAJ24826.1 - 0.051 13.8 5.3 0.084 13.1 3.7 1.2 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal RRM_1 PF00076.17 OAJ24827.1 - 2.4e-31 107.1 0.0 3.9e-12 45.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ24827.1 - 5.8e-27 93.4 0.0 4.5e-10 39.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ24827.1 - 4.5e-18 64.8 0.0 2.1e-06 27.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.21 OAJ24829.1 - 2.5e-10 40.0 10.1 3.3e-05 23.9 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ24829.1 - 4.8e-07 29.6 10.0 0.0044 17.2 2.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ24829.1 - 3.7e-06 26.9 2.0 3.7e-06 26.9 1.4 3.1 4 0 0 4 4 4 1 Zinc-finger double domain AKAP2_C PF15304.1 OAJ24829.1 - 6.6 6.2 10.8 0.27 10.8 2.2 2.2 2 0 0 2 2 2 0 A-kinase anchor protein 2 C-terminus TPR_12 PF13424.1 OAJ24830.1 - 3.1e-05 23.8 10.9 0.097 12.6 0.3 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ24830.1 - 0.00072 19.1 1.4 12 6.0 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ24830.1 - 0.02 14.5 7.6 7.2 6.3 0.1 4.5 4 1 0 4 4 4 0 TPR repeat TPR_1 PF00515.23 OAJ24830.1 - 0.11 12.1 8.2 14 5.4 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ24830.1 - 0.13 12.2 15.0 1.1 9.3 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ24830.1 - 0.29 11.0 4.2 27 4.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ24830.1 - 5.4 7.8 16.6 19 6.0 1.7 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat GST_C_3 PF14497.1 OAJ24831.1 - 0.0025 18.2 0.0 0.0057 17.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Oxysterol_BP PF01237.13 OAJ24833.1 - 3.7e-56 190.1 6.8 1.1e-45 155.6 0.2 3.0 3 0 0 3 3 3 3 Oxysterol-binding protein zf-RVT PF13966.1 OAJ24834.1 - 0.016 15.5 0.3 0.025 14.8 0.2 1.3 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase ADH_zinc_N PF00107.21 OAJ24836.1 - 2.5e-28 98.1 0.3 5.5e-28 97.1 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ24836.1 - 7.7e-13 49.4 0.7 1.8e-12 48.2 0.0 2.0 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ24836.1 - 2.8e-09 36.7 0.0 4e-08 32.9 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Trp_syntA PF00290.15 OAJ24837.1 - 1e-80 270.0 0.1 2e-80 269.0 0.0 1.5 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 OAJ24837.1 - 2.9e-46 158.0 0.5 6e-46 157.0 0.3 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 OAJ24837.1 - 1.1e-05 24.8 0.1 4e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein PA PF02225.17 OAJ24837.1 - 0.0028 17.2 2.3 0.021 14.5 0.0 2.6 2 1 0 2 2 2 1 PA domain DFP PF04127.10 OAJ24837.1 - 0.02 14.5 0.1 0.31 10.6 0.1 2.4 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein MULE PF10551.4 OAJ24838.1 - 1.9e-05 24.7 0.0 6.5e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 MULE transposase domain DivIVA PF05103.8 OAJ24838.1 - 0.27 11.2 3.7 6.5 6.8 0.1 2.7 2 0 0 2 2 2 0 DivIVA protein Amidohydro_1 PF01979.15 OAJ24840.1 - 2.1e-42 145.9 0.0 3.6e-29 102.4 0.0 2.1 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 OAJ24840.1 - 9.3e-08 31.6 0.0 2.1e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 OAJ24840.1 - 2.4e-05 24.0 0.1 9.2e-05 22.1 0.1 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 OAJ24840.1 - 2.6e-05 24.3 0.4 0.35 10.8 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase A_deaminase PF00962.17 OAJ24840.1 - 0.00042 19.3 0.0 0.0007 18.6 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Pkinase PF00069.20 OAJ24841.1 - 2.2e-66 223.6 0.0 4.8e-66 222.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ24841.1 - 3.2e-52 177.1 0.0 4.8e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ24841.1 - 8.3e-07 28.2 0.0 7.4e-05 21.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like C1_1 PF00130.17 OAJ24841.1 - 0.00058 19.5 7.6 0.001 18.7 5.2 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CH PF00307.26 OAJ24841.1 - 0.004 17.1 0.0 0.0097 15.9 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 OAJ24841.1 - 0.057 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 CDC24 Calponin PHD PF00628.24 OAJ24841.1 - 0.37 10.5 7.0 0.67 9.6 4.9 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 OAJ24841.1 - 1.2 8.9 7.2 2.2 8.1 5.0 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 NTP_transf_2 PF01909.18 OAJ24842.1 - 0.00026 21.2 0.0 0.00047 20.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF3395 PF11875.3 OAJ24843.1 - 1.1e-33 116.0 0.0 2.6e-33 114.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 OAJ24843.1 - 9.6e-22 76.4 0.6 2.5e-21 75.1 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain Surp PF01805.15 OAJ24844.1 - 1.8e-12 46.7 0.3 3.9e-12 45.6 0.2 1.5 1 0 0 1 1 1 1 Surp module RRM_6 PF14259.1 OAJ24844.1 - 2.3e-06 27.5 0.0 5.3e-05 23.1 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ24844.1 - 1.7e-05 24.3 0.0 0.17 11.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTK3 PF12243.3 OAJ24844.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 RRM_5 PF13893.1 OAJ24844.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.22 OAJ24845.1 - 2.3e-48 161.8 4.6 3.5e-17 61.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PMSR PF01625.16 OAJ24846.1 - 1.4e-54 184.1 0.3 1.7e-54 183.9 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase GatB_N PF02934.10 OAJ24847.1 - 3.6e-84 282.0 0.0 1.4e-83 280.1 0.0 1.9 1 1 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 OAJ24847.1 - 3.5e-26 91.7 0.0 1.3e-14 54.1 0.0 2.4 2 0 0 2 2 2 2 GatB domain UvrD_C PF13361.1 OAJ24848.1 - 1.9e-15 57.2 0.1 5e-15 55.8 0.1 1.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 OAJ24848.1 - 7.6e-11 41.8 0.7 7.6e-11 41.8 0.5 3.2 4 1 0 4 4 4 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 OAJ24848.1 - 3.6e-09 36.7 0.0 1.1e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 OAJ24848.1 - 1.5e-07 31.2 0.0 0.0011 18.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 OAJ24848.1 - 1.8e-07 30.9 0.1 0.084 12.3 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 OAJ24848.1 - 0.0021 17.7 0.0 0.0064 16.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 OAJ24848.1 - 0.011 15.8 1.1 12 6.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.20 OAJ24854.1 - 8.2e-53 179.2 0.0 1.1e-29 103.4 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ24854.1 - 8.3e-22 77.4 0.1 1.5e-13 50.4 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ24854.1 - 0.00019 20.5 0.0 0.074 11.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 OAJ24854.1 - 0.002 17.8 0.0 0.0068 16.1 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family YukC PF10140.4 OAJ24854.1 - 0.092 11.3 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC zf-C2H2_4 PF13894.1 OAJ24856.1 - 6.1e-08 32.4 7.9 0.0016 18.6 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 OAJ24856.1 - 0.00019 21.5 12.5 0.0019 18.4 0.5 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAJ24856.1 - 0.069 13.4 0.8 6.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-met PF12874.2 OAJ24856.1 - 0.11 12.7 2.4 0.28 11.4 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Pkinase PF00069.20 OAJ24857.1 - 1.8e-60 204.3 0.0 1.5e-41 142.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ24857.1 - 9.7e-26 90.3 0.0 1.1e-19 70.5 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ24857.1 - 0.00085 18.3 0.0 0.00085 18.3 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Pox_ser-thr_kin PF05445.6 OAJ24857.1 - 0.067 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 OAJ24857.1 - 0.087 12.5 0.0 0.087 12.5 0.0 4.1 2 1 2 4 4 4 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ24857.1 - 0.17 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Med15 PF09606.5 OAJ24857.1 - 0.45 8.6 99.1 0.75 7.9 68.7 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Formyl_trans_N PF00551.14 OAJ24858.1 - 0.001 18.6 0.3 0.0012 18.3 0.2 1.1 1 0 0 1 1 1 1 Formyl transferase DUF4551 PF15087.1 OAJ24858.1 - 0.43 8.9 4.2 0.49 8.6 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Amidohydro_2 PF04909.9 OAJ24859.1 - 0.0038 16.8 0.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase RIC1 PF07064.8 OAJ24861.1 - 1.3e-69 234.5 1.6 1.5e-40 139.2 0.1 3.1 3 0 0 3 3 3 3 RIC1 Ribophorin_II PF05817.9 OAJ24862.1 - 0.00017 20.0 1.8 0.00027 19.2 1.3 1.3 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Glyoxalase_2 PF12681.2 OAJ24864.1 - 4.1e-11 43.4 0.0 4.2e-10 40.1 0.0 2.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 OAJ24864.1 - 7.4e-05 22.7 0.0 0.00033 20.6 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BMF PF15185.1 OAJ24864.1 - 0.088 12.0 2.0 0.16 11.2 1.4 1.3 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis DUF3235 PF11574.3 OAJ24864.1 - 0.42 10.8 5.4 1.4 9.1 3.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) SIMPL PF04402.9 OAJ24864.1 - 8.1 6.2 12.9 12 5.6 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Pkinase PF00069.20 OAJ24865.1 - 1.6e-08 34.0 0.0 1.8e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ24865.1 - 2e-07 30.3 0.0 0.0048 16.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 OAJ24865.1 - 0.00068 18.7 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ24865.1 - 0.0022 17.7 0.2 0.0055 16.4 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAJ24865.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase GalP_UDP_transf PF01087.17 OAJ24866.1 - 2.8e-60 203.5 0.2 4.1e-60 202.9 0.1 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 OAJ24866.1 - 1.3e-39 135.4 0.0 4.5e-20 71.8 0.0 2.6 3 0 0 3 3 3 2 Galactose-1-phosphate uridyl transferase, C-terminal domain WD40 PF00400.27 OAJ24867.1 - 5e-09 35.6 2.0 0.38 10.7 0.0 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat AT_hook PF02178.14 OAJ24867.1 - 0.0007 18.9 90.4 1.9 8.4 4.7 8.5 7 0 0 7 7 7 7 AT hook motif Apq12 PF12716.2 OAJ24868.1 - 0.21 11.2 2.3 0.52 10.0 1.6 1.6 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Hepatitis_core PF00906.15 OAJ24868.1 - 7.4 6.1 11.8 4 7.0 1.3 2.2 2 0 0 2 2 2 0 Hepatitis core antigen PBP1_TM PF14812.1 OAJ24868.1 - 9.4 6.6 11.6 0.42 10.9 2.5 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Rpn3_C PF08375.6 OAJ24869.1 - 5.2e-22 78.0 1.0 5.2e-22 78.0 0.7 2.3 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 OAJ24869.1 - 6.4e-17 61.7 0.1 1.7e-16 60.4 0.1 1.7 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 OAJ24869.1 - 0.0086 15.9 1.8 0.1 12.5 0.4 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat PCI_Csn8 PF10075.4 OAJ24869.1 - 0.013 15.2 0.9 0.026 14.3 0.0 1.8 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 PCI PF01399.22 OAJ24870.1 - 0.0009 19.5 0.0 0.0032 17.7 0.0 1.9 1 1 0 1 1 1 1 PCI domain DUF3767 PF12597.3 OAJ24871.1 - 2.9e-29 101.1 0.1 3.4e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) SSB PF00436.20 OAJ24872.1 - 1.3e-14 53.8 0.0 1.7e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family XRN_N PF03159.13 OAJ24874.1 - 1.7e-105 351.7 0.0 2.9e-105 350.8 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 OAJ24874.1 - 0.0013 18.5 2.8 0.0036 17.1 1.9 1.8 1 0 0 1 1 1 1 Zinc knuckle DUF2497 PF10691.4 OAJ24874.1 - 0.1 12.5 0.3 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) ETC_C1_NDUFA5 PF04716.9 OAJ24876.1 - 5.4e-16 57.8 0.3 9.5e-16 57.0 0.2 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region Prefoldin_2 PF01920.15 OAJ24876.1 - 0.0012 18.5 0.3 0.002 17.8 0.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit Abhydrolase_6 PF12697.2 OAJ24877.1 - 6.3e-29 101.4 3.3 3.3e-28 99.1 2.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ24877.1 - 3.2e-10 39.9 0.1 1.3e-06 28.1 0.1 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ24877.1 - 3.5e-10 39.8 0.0 1e-09 38.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ24877.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase TPP_enzyme_N PF02776.13 OAJ24878.1 - 1e-34 119.4 0.1 1.5e-34 118.9 0.1 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAJ24878.1 - 1.6e-27 95.9 0.0 3.2e-26 91.7 0.0 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 OAJ24878.1 - 6e-16 58.3 0.2 1.1e-14 54.2 0.0 2.8 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Cutinase PF01083.17 OAJ24879.1 - 4.8e-10 39.4 0.0 7.2e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Cutinase DUF21 PF01595.15 OAJ24883.1 - 3.1e-36 124.3 0.9 5.1e-36 123.6 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 OAJ24883.1 - 8.4e-09 35.0 0.1 0.0073 16.0 0.0 2.9 3 0 0 3 3 3 2 CBS domain PIN_4 PF13638.1 OAJ24884.1 - 1.5e-18 67.1 2.1 2.1e-18 66.6 0.1 2.2 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.4 OAJ24884.1 - 3.2e-11 42.9 0.0 6.1e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain eIF3_subunit PF08597.5 OAJ24884.1 - 0.079 12.5 10.6 0.16 11.5 7.3 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DNA_pol_phi PF04931.8 OAJ24884.1 - 0.96 7.1 6.5 1.4 6.5 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi rve PF00665.21 OAJ24885.1 - 1.7e-15 57.2 0.0 3.2e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ24885.1 - 5.8e-15 55.2 0.0 1.2e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Denso_VP4 PF02336.10 OAJ24885.1 - 0.4 9.6 0.0 0.67 8.8 0.0 1.3 1 0 0 1 1 1 0 Capsid protein VP4 DPBB_1 PF03330.13 OAJ24887.1 - 0.00025 20.9 1.0 0.00086 19.2 0.7 2.0 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ24887.1 - 0.00047 19.8 0.1 0.0007 19.2 0.1 1.3 1 0 0 1 1 1 1 Barwin family RVT_1 PF00078.22 OAJ24888.1 - 8e-18 64.5 0.0 1.5e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ24888.1 - 1.6e-16 60.4 0.0 5.7e-16 58.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain CpcD PF01383.16 OAJ24888.1 - 0.067 13.3 0.0 0.69 10.1 0.0 2.3 2 0 0 2 2 2 0 CpcD/allophycocyanin linker domain NT5C PF06941.7 OAJ24888.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) BNIP2 PF12496.3 OAJ24889.1 - 0.0038 17.3 1.0 0.0038 17.3 0.7 2.3 2 0 0 2 2 2 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CDC45 PF02724.9 OAJ24889.1 - 0.58 8.1 2.6 1.2 7.0 1.8 1.5 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 OAJ24889.1 - 2.2 7.8 7.0 4.8 6.7 1.0 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region TFR_dimer PF04253.10 OAJ24891.1 - 1.3e-13 50.5 0.0 5e-13 48.7 0.0 1.9 1 1 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 OAJ24891.1 - 1.6e-12 47.5 0.5 3.8e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 OAJ24891.1 - 1.6e-05 24.5 0.1 3.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 OAJ24891.1 - 0.0027 17.2 0.0 0.0065 15.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Cep57_CLD PF14073.1 OAJ24891.1 - 0.15 11.8 0.1 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 SOBP PF15279.1 OAJ24892.1 - 2.5 8.4 7.8 4.9 7.4 5.4 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein tRNA-synt_2 PF00152.15 OAJ24893.1 - 1.8e-84 283.4 0.0 2.2e-84 283.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAJ24893.1 - 1e-10 41.2 0.0 3.8e-10 39.4 0.0 2.1 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 OAJ24893.1 - 4.9e-08 32.4 0.1 8.7e-05 21.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 OAJ24893.1 - 0.0074 15.8 0.1 1.6 8.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti-like PF12869.2 OAJ24893.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 tRNA_anti-like PS-DH PF14765.1 OAJ24893.1 - 0.23 10.5 6.8 0.42 9.7 4.7 1.3 1 0 0 1 1 1 0 Polyketide synthase dehydratase Actin PF00022.14 OAJ24895.1 - 1.2e-49 168.7 0.0 5.4e-49 166.6 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 OAJ24895.1 - 0.0066 15.0 0.0 0.016 13.7 0.0 1.6 1 0 0 1 1 1 1 MreB/Mbl protein SDA1 PF05285.7 OAJ24895.1 - 0.63 9.2 15.4 2.1 7.5 9.9 2.0 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.5 OAJ24895.1 - 9.1 5.2 17.6 23 3.8 12.2 1.6 1 0 0 1 1 1 0 BUD22 Peptidase_M28 PF04389.12 OAJ24896.1 - 1.3e-12 47.8 0.0 2.7e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 OAJ24896.1 - 1.4e-07 31.1 0.0 3.5e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 PA domain TFR_dimer PF04253.10 OAJ24896.1 - 1.6e-07 30.9 0.0 5.9e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 Transferrin receptor-like dimerisation domain DUF1765 PF08578.5 OAJ24897.1 - 1.4e-28 99.5 1.6 2.1e-28 98.8 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) GATase_5 PF13507.1 OAJ24898.1 - 2.9e-91 304.9 0.0 4.7e-91 304.2 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 OAJ24898.1 - 6.1e-43 146.4 3.0 1.5e-21 77.0 0.0 2.7 2 1 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 OAJ24898.1 - 4e-21 75.0 0.0 1.3e-20 73.3 0.0 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Tannase PF07519.6 OAJ24903.1 - 7.3e-40 137.0 0.1 1.3e-39 136.2 0.1 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase Zip PF02535.17 OAJ24903.1 - 0.0046 16.0 2.7 0.0066 15.4 1.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter SelP_N PF04592.9 OAJ24903.1 - 3 7.1 11.0 5.8 6.2 7.6 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Tannase PF07519.6 OAJ24904.1 - 3.4e-64 217.3 0.0 2.4e-62 211.1 0.0 2.2 1 1 0 1 1 1 1 Tannase and feruloyl esterase Tannase PF07519.6 OAJ24905.1 - 6.7e-40 137.1 0.1 7.3e-38 130.4 0.1 2.0 1 1 0 1 1 1 1 Tannase and feruloyl esterase Mob1_phocein PF03637.12 OAJ24906.1 - 1.4e-72 243.0 0.1 1.7e-72 242.7 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family Pyridoxal_deC PF00282.14 OAJ24907.1 - 3.9e-71 239.4 0.0 5.1e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 OAJ24907.1 - 1.7e-05 24.1 0.0 2.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 OAJ24907.1 - 9.1e-05 21.3 0.0 0.00016 20.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 OAJ24907.1 - 0.0064 15.0 0.0 0.0098 14.4 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain RRM_6 PF14259.1 OAJ24908.1 - 2.4e-34 117.1 0.2 4.4e-08 32.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ24908.1 - 4.5e-27 93.4 0.8 5e-07 29.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ24908.1 - 5.1e-20 71.0 0.2 3.8e-05 23.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ24908.1 - 0.0018 18.1 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif DUF202 PF02656.10 OAJ24909.1 - 8.4e-15 54.7 0.3 3.9e-14 52.6 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF202) Yae1_N PF09811.4 OAJ24910.1 - 2e-07 30.3 4.8 4.6e-07 29.2 3.3 1.7 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RRM_1 PF00076.17 OAJ24910.1 - 0.00048 19.7 0.1 0.072 12.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zip PF02535.17 OAJ24910.1 - 0.83 8.5 7.2 1.6 7.6 5.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 OAJ24910.1 - 1.3 8.8 6.9 2.9 7.7 4.8 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AMP-binding PF00501.23 OAJ24911.1 - 9.3e-78 261.4 0.3 6.9e-56 189.4 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ24911.1 - 6.6e-10 39.7 0.0 1.7e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.1 OAJ24911.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain ETF PF01012.16 OAJ24911.1 - 0.043 13.5 0.1 0.08 12.6 0.1 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein domain DIL PF01843.14 OAJ24912.1 - 2.1e-19 69.3 0.2 4.4e-19 68.3 0.1 1.6 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.2 OAJ24912.1 - 6.3e-16 58.4 0.0 3.2e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ24912.1 - 3.3e-12 45.5 0.3 9.8e-07 28.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 OAJ24912.1 - 5.1e-11 41.6 0.1 0.00013 21.8 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 OAJ24912.1 - 1.1e-10 41.6 0.1 2.9e-09 37.1 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ24912.1 - 1.1e-10 41.3 0.3 1.1e-07 31.7 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Phosphoprotein PF00922.12 OAJ24912.1 - 9 5.4 9.5 0.29 10.3 0.1 2.7 3 0 0 3 3 3 0 Vesiculovirus phosphoprotein UPF0061 PF02696.9 OAJ24914.1 - 2.2e-79 267.0 0.0 3.8e-79 266.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family adh_short PF00106.20 OAJ24915.1 - 1.6e-25 89.9 1.0 2.9e-25 89.1 0.7 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ24915.1 - 5.1e-10 39.3 2.6 8.3e-10 38.6 0.3 2.3 2 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 OAJ24915.1 - 6.7e-08 32.5 0.0 9.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HHH_5 PF14520.1 OAJ24915.1 - 0.027 14.6 0.0 24 5.1 0.0 3.1 3 1 0 3 3 3 0 Helix-hairpin-helix domain Transket_pyr PF02779.19 OAJ24916.1 - 7e-47 159.2 0.0 1.3e-46 158.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 OAJ24916.1 - 1.3e-38 131.7 0.2 1e-37 128.8 0.0 2.4 3 0 0 3 3 3 1 Transketolase, C-terminal domain Med3 PF11593.3 OAJ24916.1 - 0.32 10.1 12.0 0.39 9.9 8.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal KTI12 PF08433.5 OAJ24917.1 - 5.7e-54 183.1 0.0 9.2e-54 182.4 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 OAJ24917.1 - 3.4e-08 33.4 0.2 7.3e-08 32.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ24917.1 - 0.0015 18.8 0.2 0.011 16.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain Aldedh PF00171.17 OAJ24918.1 - 7.6e-73 245.4 0.0 9.2e-73 245.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CENP-F_leu_zip PF10473.4 OAJ24919.1 - 0.012 15.4 21.7 0.012 15.4 15.0 6.8 2 1 6 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 OAJ24919.1 - 0.022 13.9 8.4 0.37 9.9 0.0 3.6 2 1 1 3 3 3 0 Reovirus sigma C capsid protein WEMBL PF05701.6 OAJ24919.1 - 0.28 9.6 83.7 1.6 7.0 57.4 2.8 1 1 0 1 1 1 0 Weak chloroplast movement under blue light NPV_P10 PF05531.7 OAJ24919.1 - 0.86 9.9 16.5 18 5.6 0.0 5.7 2 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 OAJ24919.1 - 1.5 8.6 24.6 3.5 7.4 0.0 4.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF812 PF05667.6 OAJ24919.1 - 1.9 6.9 61.6 0.025 13.0 14.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF812) NOZZLE PF08744.5 OAJ24920.1 - 0.056 12.7 2.9 0.042 13.2 0.5 1.7 2 0 0 2 2 2 0 Plant transcription factor NOZZLE Lyase_1 PF00206.15 OAJ24921.1 - 7.5e-93 311.1 0.0 1.2e-92 310.5 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 OAJ24921.1 - 2.2e-28 98.1 0.1 5.2e-28 96.9 0.1 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal UAA PF08449.6 OAJ24922.1 - 1.8e-11 43.5 14.3 2.7e-07 29.8 0.2 2.1 2 0 0 2 2 2 2 UAA transporter family TPT PF03151.11 OAJ24922.1 - 6.8e-11 42.0 2.7 6.8e-11 42.0 1.9 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family PHO4 PF01384.15 OAJ24922.1 - 0.0017 17.1 0.2 0.0017 17.1 0.2 2.4 2 1 0 2 2 2 1 Phosphate transporter family EamA PF00892.15 OAJ24922.1 - 1.6 8.7 23.4 0.061 13.3 2.1 2.5 2 1 0 2 2 2 0 EamA-like transporter family zf-RING_2 PF13639.1 OAJ24923.1 - 9.9e-09 34.8 7.1 9.7e-08 31.7 3.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ24923.1 - 5.8e-08 32.6 5.0 5.8e-08 32.6 3.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ24923.1 - 1.1e-06 28.1 5.8 1.1e-06 28.1 4.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ24923.1 - 3.5e-06 26.6 7.5 2.4e-05 23.9 3.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAJ24923.1 - 0.00011 21.8 3.9 0.00027 20.5 2.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 OAJ24923.1 - 0.00018 21.1 5.9 0.00018 21.1 4.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain DUF1644 PF07800.7 OAJ24923.1 - 0.00087 19.1 1.5 0.1 12.4 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1644) zf-C3HC4_4 PF15227.1 OAJ24923.1 - 0.0018 18.1 6.2 0.0018 18.1 4.3 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING BMFP PF04380.8 OAJ24925.1 - 0.017 15.2 4.4 0.017 15.2 3.0 5.2 7 1 0 7 7 7 0 Membrane fusogenic activity GLE1 PF07817.8 OAJ24925.1 - 0.055 12.3 3.9 0.17 10.7 2.7 1.8 1 0 0 1 1 1 0 GLE1-like protein Spc24 PF08286.6 OAJ24925.1 - 5.5 6.7 28.0 0.027 14.1 0.7 4.6 3 2 3 6 6 6 0 Spc24 subunit of Ndc80 HSP70 PF00012.15 OAJ24929.1 - 2.2e-40 138.1 10.3 2.9e-36 124.6 0.0 4.1 3 1 0 3 3 3 2 Hsp70 protein Myb_DNA-bind_3 PF12776.2 OAJ24930.1 - 2.7e-12 47.1 0.6 2.7e-12 47.1 0.4 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF1752 PF08550.5 OAJ24930.1 - 8.1e-10 38.1 3.2 1.5e-09 37.2 2.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Daxx PF03344.10 OAJ24930.1 - 0.015 13.8 1.7 0.046 12.2 1.2 1.8 1 0 0 1 1 1 0 Daxx Family Myb_DNA-bind_4 PF13837.1 OAJ24930.1 - 0.15 12.1 4.2 0.39 10.8 2.9 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Nop14 PF04147.7 OAJ24930.1 - 2.3 6.0 6.2 4.7 5.0 4.3 1.4 1 0 0 1 1 1 0 Nop14-like family GMC_oxred_N PF00732.14 OAJ24931.1 - 4.6e-61 206.5 0.0 1.1e-60 205.3 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ24931.1 - 5.8e-31 107.7 0.1 1.2e-30 106.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAJ24931.1 - 5e-08 32.2 0.0 1.4e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ24931.1 - 6e-05 22.0 0.0 0.00048 19.0 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 OAJ24931.1 - 0.00017 21.5 0.0 0.00041 20.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAJ24931.1 - 0.00024 21.2 0.0 0.078 13.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ24931.1 - 0.00043 20.2 0.2 0.051 13.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAJ24931.1 - 0.0012 17.8 0.2 0.0018 17.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 OAJ24931.1 - 0.023 13.1 0.5 0.041 12.3 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 OAJ24931.1 - 0.12 12.8 0.2 1.6 9.2 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RRM_1 PF00076.17 OAJ24932.1 - 5.4e-20 70.7 0.0 5.2e-12 45.2 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ24932.1 - 9.7e-17 60.7 0.0 1.8e-09 37.4 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ24932.1 - 7.1e-10 38.5 0.1 0.0013 18.5 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PPR_2 PF13041.1 OAJ24933.1 - 0.011 15.6 0.0 0.18 11.7 0.0 2.8 2 0 0 2 2 2 0 PPR repeat family Pkinase PF00069.20 OAJ24934.1 - 1.5e-73 247.1 0.0 2e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ24934.1 - 1.5e-31 109.4 0.0 2.3e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ24934.1 - 3.4e-07 29.5 0.3 0.00083 18.4 0.1 2.4 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.17 OAJ24934.1 - 0.00068 19.0 0.1 0.0012 18.2 0.1 1.4 1 0 0 1 1 1 1 RIO1 family SEEEED PF14797.1 OAJ24934.1 - 0.12 12.5 11.2 0.18 11.9 7.8 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex zf-CCCH_2 PF14608.1 OAJ24935.1 - 1.6e-07 31.0 19.1 4.3e-06 26.5 4.3 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type Ank_2 PF12796.2 OAJ24935.1 - 2.8e-07 30.7 0.0 5.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ24935.1 - 5.6e-06 25.8 0.0 1.5e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 OAJ24935.1 - 9.5e-05 22.5 0.1 0.00044 20.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ24935.1 - 0.0001 22.2 0.0 0.00024 21.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat zf-CCCH PF00642.19 OAJ24935.1 - 0.0007 19.2 11.5 0.024 14.3 1.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_4 PF13637.1 OAJ24935.1 - 0.0015 18.9 0.0 0.0041 17.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AMP-binding PF00501.23 OAJ24937.1 - 2.4e-72 243.6 0.0 3.4e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.19 OAJ24937.1 - 1.8e-05 23.9 7.2 0.61 9.6 0.2 7.1 8 1 0 8 8 8 2 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.20 OAJ24937.1 - 0.0056 16.9 0.0 0.015 15.5 0.0 1.8 1 1 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.1 OAJ24937.1 - 3.5 7.2 9.3 0.87 9.2 0.2 4.6 6 1 1 7 7 7 0 Hexapeptide repeat of succinyl-transferase HLH PF00010.21 OAJ24939.1 - 0.15 11.7 0.7 0.29 10.8 0.5 1.4 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Sec66 PF09802.4 OAJ24939.1 - 0.21 10.9 1.0 0.32 10.3 0.7 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 Dopey_N PF04118.9 OAJ24940.1 - 9.3e-106 353.0 0.0 2e-105 351.9 0.0 1.5 1 0 0 1 1 1 1 Dopey, N-terminal UCR_hinge PF02320.11 OAJ24941.1 - 2e-07 30.8 2.3 3.4e-07 30.1 1.6 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein GDNF PF02351.11 OAJ24941.1 - 0.043 14.3 0.8 0.085 13.3 0.5 1.4 1 0 0 1 1 1 0 GDNF/GAS1 domain SART-1 PF03343.8 OAJ24941.1 - 0.6 8.3 7.0 0.67 8.2 4.9 1.0 1 0 0 1 1 1 0 SART-1 family Nop14 PF04147.7 OAJ24941.1 - 3 5.6 8.6 3.1 5.5 6.0 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 OAJ24941.1 - 6 5.2 11.7 6.5 5.1 8.1 1.1 1 0 0 1 1 1 0 Daxx Family DUF3292 PF11696.3 OAJ24942.1 - 2.7e-161 537.6 0.0 3.3e-73 246.6 0.0 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF3292) Herpes_DNAp_acc PF04929.7 OAJ24942.1 - 1.6 7.5 3.0 3.4 6.5 2.1 1.5 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Solute_trans_a PF03619.11 OAJ24943.1 - 4e-67 226.4 12.0 5e-67 226.1 8.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PepSY_TM_2 PF13703.1 OAJ24943.1 - 0.016 15.3 0.1 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 PepSY-associated TM helix Mon1 PF03164.9 OAJ24944.1 - 2.9e-63 213.9 0.0 1.8e-20 72.9 0.0 4.1 4 0 0 4 4 4 4 Trafficking protein Mon1 Methyltransf_25 PF13649.1 OAJ24945.1 - 0.046 14.0 0.0 16 5.9 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain GST_N PF02798.15 OAJ24952.1 - 8.4e-11 41.8 0.0 1.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 OAJ24952.1 - 1.4e-10 41.2 0.0 2.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ24952.1 - 2.8e-10 40.0 0.0 4.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ24952.1 - 3.6e-09 36.5 0.0 4.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ24952.1 - 5.7e-09 35.7 0.1 1.1e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ24952.1 - 9.4e-07 29.2 0.1 1.5e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3220 PF11516.3 OAJ24952.1 - 0.092 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) GST_N PF02798.15 OAJ24954.1 - 8.4e-11 41.8 0.0 1.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 OAJ24954.1 - 1.4e-10 41.2 0.0 2.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ24954.1 - 2.8e-10 40.0 0.0 4.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ24954.1 - 3.6e-09 36.5 0.0 4.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ24954.1 - 5.7e-09 35.7 0.1 1.1e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ24954.1 - 9.4e-07 29.2 0.1 1.5e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3220 PF11516.3 OAJ24954.1 - 0.092 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) TMEM154 PF15102.1 OAJ24955.1 - 0.049 13.3 1.5 0.15 11.7 1.0 1.9 1 0 0 1 1 1 0 TMEM154 protein family Ebp2 PF05890.7 OAJ24956.1 - 2.9e-71 239.9 15.1 2.9e-71 239.9 10.4 2.6 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DUF573 PF04504.9 OAJ24956.1 - 0.047 13.9 1.4 0.12 12.6 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF573 DUF3295 PF11702.3 OAJ24956.1 - 4.4 6.1 22.9 8.3 5.2 15.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Polysacc_deac_1 PF01522.16 OAJ24959.1 - 1.2e-23 83.0 0.0 1.9e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase LRR_7 PF13504.1 OAJ24960.1 - 0.00077 19.2 2.6 4.7 7.8 0.0 5.7 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 OAJ24960.1 - 0.0011 18.7 5.3 6.4 7.1 0.0 5.9 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.2 OAJ24960.1 - 0.015 14.8 0.3 18 5.1 0.0 4.6 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 OAJ24960.1 - 0.34 11.1 9.9 0.81 9.9 0.0 5.2 5 1 1 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.1 OAJ24960.1 - 0.4 10.4 8.3 4.2 7.1 0.0 4.4 4 2 0 4 4 4 0 Leucine rich repeat MFS_1 PF07690.11 OAJ24961.1 - 1.7e-17 63.2 31.4 1.7e-17 63.2 21.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 OAJ24961.1 - 1.6e-14 53.7 7.0 1.6e-14 53.7 4.9 2.8 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 MerC PF03203.9 OAJ24961.1 - 0.027 14.8 1.8 0.027 14.8 1.2 3.1 3 2 1 4 4 4 0 MerC mercury resistance protein MFS_1 PF07690.11 OAJ24962.1 - 1.6e-40 138.9 46.3 2.4e-40 138.3 29.9 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAJ24962.1 - 3.7e-17 61.7 10.6 3.7e-17 61.7 7.3 1.7 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 OAJ24962.1 - 1.9e-12 46.4 13.4 1.9e-12 46.4 9.3 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter bZIP_2 PF07716.10 OAJ24963.1 - 1.6e-08 34.2 12.7 1.6e-08 34.2 8.8 3.3 2 1 0 2 2 1 1 Basic region leucine zipper Spore_coat_CotO PF14153.1 OAJ24963.1 - 7.8e-05 22.1 11.0 7.8e-05 22.1 7.6 2.0 2 0 0 2 2 2 1 Spore coat protein CotO Ycf1 PF05758.7 OAJ24963.1 - 0.00053 17.8 5.9 0.00089 17.1 4.1 1.2 1 0 0 1 1 1 1 Ycf1 Zip PF02535.17 OAJ24963.1 - 0.019 14.0 2.7 0.032 13.2 1.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SPX PF03105.14 OAJ24963.1 - 0.021 14.6 13.5 0.045 13.5 5.8 2.3 2 0 0 2 2 2 0 SPX domain FimP PF09766.4 OAJ24963.1 - 0.17 10.8 29.5 0.51 9.3 20.5 1.7 1 0 0 1 1 1 0 Fms-interacting protein Plasmodium_Vir PF05795.6 OAJ24963.1 - 0.2 10.8 2.0 0.41 9.8 1.4 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PAT1 PF09770.4 OAJ24963.1 - 0.21 9.7 55.4 0.45 8.7 38.4 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.11 OAJ24963.1 - 0.28 9.7 0.4 0.39 9.2 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3373 PF11853.3 OAJ24963.1 - 1.6 7.1 13.1 2.9 6.3 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Band_3_cyto PF07565.8 OAJ24963.1 - 1.6 8.1 19.5 3.1 7.2 13.5 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CDK5_activator PF03261.10 OAJ24963.1 - 2.9 7.1 17.2 5 6.3 11.9 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein IncA PF04156.9 OAJ24963.1 - 5.9 6.4 36.9 4.5 6.8 20.1 2.5 2 0 0 2 2 2 0 IncA protein XPG_N PF00752.12 OAJ24964.1 - 8.2e-35 119.1 0.0 1.5e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 OAJ24964.1 - 5.2e-30 103.3 0.0 1.1e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 OAJ24964.1 - 1.1e-07 32.0 0.0 2.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 OAJ24964.1 - 0.024 14.7 0.0 0.064 13.4 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_2 PF12826.2 OAJ24964.1 - 0.095 12.6 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Transposase_20 PF02371.11 OAJ24964.1 - 0.097 12.7 0.0 0.65 10.1 0.0 2.2 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family Peptidase_M20 PF01546.23 OAJ24965.1 - 6.2e-23 81.2 0.0 1e-22 80.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 OAJ24965.1 - 1.5e-10 40.8 1.2 1.5e-09 37.6 0.8 2.4 1 1 0 1 1 1 1 Peptidase dimerisation domain ICA69 PF04629.9 OAJ24965.1 - 0.029 14.3 0.2 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Islet cell autoantigen ICA69, C-terminal domain MFS_1 PF07690.11 OAJ24966.1 - 2.3e-32 112.0 29.4 9.4e-31 106.7 5.4 2.9 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ24966.1 - 1.1e-09 37.4 1.1 1.1e-09 37.4 0.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Nucleoplasmin PF03066.10 OAJ24966.1 - 0.1 12.1 0.9 0.22 11.0 0.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 OAJ24966.1 - 0.16 9.8 7.2 0.24 9.2 5.0 1.1 1 0 0 1 1 1 0 Nop14-like family PGA2 PF07543.7 OAJ24966.1 - 3.6 7.3 8.1 17 5.2 0.1 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 NOA36 PF06524.7 OAJ24966.1 - 8.5 5.5 6.2 14 4.8 4.3 1.2 1 0 0 1 1 1 0 NOA36 protein Pro_CA PF00484.14 OAJ24968.1 - 8.6e-39 132.9 0.0 1.2e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_1 PF00561.15 OAJ24968.1 - 0.0072 15.9 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2922 PF11148.3 OAJ24968.1 - 0.06 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) Sda PF08970.5 OAJ24968.1 - 0.079 12.4 0.2 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Sporulation inhibitor A UreF PF01730.11 OAJ24969.1 - 4.9e-09 36.4 4.1 9.9e-08 32.2 2.8 2.4 1 1 0 1 1 1 1 UreF NUDE_C PF04880.8 OAJ24970.1 - 7.9e-10 39.3 16.5 7.9e-10 39.3 11.5 3.4 2 1 1 3 3 2 1 NUDE protein, C-terminal conserved region DUF3584 PF12128.3 OAJ24970.1 - 7.7e-05 20.2 15.3 0.00011 19.7 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 OAJ24970.1 - 0.0013 18.4 23.4 0.022 14.5 2.3 2.5 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein DivIC PF04977.10 OAJ24970.1 - 0.0021 17.4 14.9 0.17 11.3 0.4 3.7 2 1 1 3 3 3 2 Septum formation initiator Filament PF00038.16 OAJ24970.1 - 0.0032 16.9 7.6 0.0032 16.9 5.3 2.3 1 1 1 2 2 2 1 Intermediate filament protein DUF948 PF06103.6 OAJ24970.1 - 0.0053 16.6 7.0 0.74 9.7 0.5 3.6 3 1 1 4 4 4 2 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.6 OAJ24970.1 - 0.011 16.1 16.2 0.087 13.2 3.4 3.2 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Prefoldin_2 PF01920.15 OAJ24970.1 - 0.015 15.0 23.9 0.12 12.1 7.6 3.1 2 1 1 3 3 3 0 Prefoldin subunit Lzipper-MIP1 PF14389.1 OAJ24970.1 - 0.026 14.6 6.6 2.1 8.4 0.2 3.2 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Laminin_II PF06009.7 OAJ24970.1 - 0.036 13.8 17.6 0.025 14.3 3.5 3.5 2 1 2 4 4 4 0 Laminin Domain II Tox-PLDMTX PF15645.1 OAJ24970.1 - 0.036 14.0 1.3 0.077 13.0 0.9 1.5 1 0 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold IncA PF04156.9 OAJ24970.1 - 0.049 13.2 20.5 0.052 13.1 7.0 2.5 1 1 1 2 2 2 0 IncA protein DUF2935 PF11155.3 OAJ24970.1 - 0.063 13.3 4.2 3.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) AAA_27 PF13514.1 OAJ24970.1 - 0.086 10.5 18.0 0.086 10.5 2.3 2.0 1 1 1 2 2 2 0 AAA domain DivIVA PF05103.8 OAJ24970.1 - 0.096 12.7 14.7 0.24 11.4 0.2 3.2 3 1 0 3 3 3 0 DivIVA protein DUF904 PF06005.7 OAJ24970.1 - 0.16 12.2 25.8 0.028 14.7 3.7 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF904) DUF3452 PF11934.3 OAJ24970.1 - 0.52 9.6 2.8 3.6 6.9 1.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) NPV_P10 PF05531.7 OAJ24970.1 - 0.64 10.2 4.9 4.3 7.6 0.6 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 OAJ24970.1 - 0.81 8.8 15.8 0.015 14.5 2.9 2.6 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 OAJ24970.1 - 0.84 9.4 6.2 0.38 10.5 1.3 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.3 OAJ24970.1 - 1 9.2 20.0 0.17 11.6 2.8 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Viral_P18 PF04521.8 OAJ24970.1 - 1.5 8.2 10.4 4.1 6.8 0.2 3.4 2 1 1 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein TBPIP PF07106.8 OAJ24970.1 - 1.7 8.1 21.4 1.2 8.6 6.8 3.1 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tweety PF04906.8 OAJ24970.1 - 2.8 6.2 3.6 1.2 7.4 0.4 1.9 2 1 0 2 2 2 0 Tweety CCDC84 PF14968.1 OAJ24970.1 - 3.7 6.9 10.4 1.2 8.5 4.4 1.9 1 1 1 2 2 2 0 Coiled coil protein 84 DUF972 PF06156.8 OAJ24970.1 - 3.8 7.8 20.7 1.4 9.3 1.8 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) TMPIT PF07851.8 OAJ24970.1 - 5.8 5.8 14.6 4 6.4 3.7 2.1 1 1 1 2 2 2 0 TMPIT-like protein ADIP PF11559.3 OAJ24970.1 - 6.4 6.6 20.1 1.1 9.1 7.5 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 OAJ24970.1 - 6.8 5.5 13.8 3.6 6.4 0.5 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 OAJ24970.1 - 6.9 6.7 19.4 2.3 8.2 1.2 4.1 3 1 1 4 4 4 0 bZIP transcription factor HALZ PF02183.13 OAJ24970.1 - 6.9 6.4 8.9 1.3 8.7 0.7 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper COG2 PF06148.6 OAJ24970.1 - 7.6 6.4 14.3 0.31 10.8 1.8 3.0 3 1 1 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_GPO PF05929.6 OAJ24970.1 - 8.2 5.5 10.5 3.4 6.8 4.6 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Spc7 PF08317.6 OAJ24970.1 - 9.8 4.7 18.9 4 5.9 8.0 2.3 1 1 0 2 2 2 0 Spc7 kinetochore protein ADH_N PF08240.7 OAJ24971.1 - 1.3e-25 89.2 3.4 1.3e-25 89.2 2.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ24971.1 - 3.8e-13 49.1 0.2 6e-13 48.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ24971.1 - 5.1e-05 24.1 0.0 9.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 OAJ24971.1 - 0.00048 19.3 0.1 0.0011 18.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 OAJ24971.1 - 0.0079 15.8 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 OAJ24971.1 - 0.016 15.0 0.2 0.036 13.9 0.1 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Oxidored_nitro PF00148.14 OAJ24971.1 - 0.016 13.8 0.0 0.028 13.0 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase ELFV_dehydrog PF00208.16 OAJ24971.1 - 0.031 13.8 0.1 0.059 12.9 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.1 OAJ24971.1 - 0.053 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding AMP-binding PF00501.23 OAJ24972.1 - 4.5e-16 58.2 1.3 4.4e-15 55.0 0.9 2.0 1 1 0 1 1 1 1 AMP-binding enzyme Med5 PF08689.5 OAJ24973.1 - 8e-31 106.6 0.0 1.8e-29 102.1 0.0 2.0 1 1 0 1 1 1 1 Mediator complex subunit Med5 COesterase PF00135.23 OAJ24974.1 - 1.5e-101 340.7 0.0 2.1e-101 340.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ24974.1 - 1.1e-10 41.4 0.6 6.3e-10 38.9 0.5 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ24974.1 - 0.0065 16.2 0.1 0.038 13.7 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ24974.1 - 0.01 15.0 0.3 0.019 14.2 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family FMN_dh PF01070.13 OAJ24975.1 - 4.9e-108 361.1 0.2 2.5e-97 325.9 0.0 2.0 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.12 OAJ24975.1 - 3.8e-05 22.7 0.1 6.1e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 OAJ24975.1 - 0.00023 20.1 1.4 0.00057 18.8 0.7 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 OAJ24975.1 - 0.0062 15.6 0.8 1.4 7.8 0.0 2.4 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG TGT PF01702.13 OAJ24975.1 - 0.05 12.8 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Queuine tRNA-ribosyltransferase COesterase PF00135.23 OAJ24977.1 - 9e-24 84.0 0.0 1.2e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Ribosomal_S26e PF01283.14 OAJ24983.1 - 1.3e-51 173.5 9.3 1.7e-51 173.2 6.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 OAJ24983.1 - 0.0041 17.4 1.8 0.0099 16.2 1.2 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 OAJ24983.1 - 0.037 14.0 0.4 0.088 12.8 0.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 OAJ24983.1 - 0.038 13.8 2.9 0.094 12.5 2.0 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain DUF1918 PF08940.6 OAJ24983.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Fer4_16 PF13484.1 OAJ24983.1 - 0.11 13.2 1.9 0.23 12.2 1.3 1.6 1 1 0 1 1 1 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 OAJ24983.1 - 0.12 12.6 2.3 0.74 10.1 2.0 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.2 OAJ24983.1 - 0.12 12.2 1.3 0.12 12.2 0.9 1.8 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.22 OAJ24983.1 - 0.14 11.8 0.7 0.14 11.8 0.5 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain SCA7 PF08313.7 OAJ24983.1 - 0.21 11.2 0.3 0.21 11.2 0.2 1.9 2 0 0 2 2 2 0 SCA7, zinc-binding domain Fer4_18 PF13746.1 OAJ24983.1 - 4.1 7.9 7.5 3.6 8.0 2.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Pro_isomerase PF00160.16 OAJ24984.1 - 3.7e-44 150.6 0.0 5.6e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 OAJ24984.1 - 5.6e-08 32.3 3.9 0.0019 17.7 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 OAJ24984.1 - 0.00021 20.9 5.7 0.22 11.5 0.5 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ24984.1 - 0.47 10.1 2.7 7.5 6.3 0.2 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat HEAT_EZ PF13513.1 OAJ24986.1 - 4.7e-07 30.1 0.0 0.0011 19.4 0.0 2.8 2 1 1 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.1 OAJ24986.1 - 0.00012 22.2 0.1 0.0094 16.2 0.0 2.2 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 OAJ24986.1 - 0.00047 20.0 0.0 0.22 11.7 0.0 2.7 2 0 0 2 2 2 2 HEAT repeat Xpo1 PF08389.7 OAJ24986.1 - 0.066 13.1 0.0 0.88 9.4 0.0 2.3 1 1 2 3 3 3 0 Exportin 1-like protein adh_short PF00106.20 OAJ24987.1 - 6.4e-16 58.7 0.1 1.1e-15 57.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ24987.1 - 5.9e-07 29.3 0.0 1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ24987.1 - 9.5e-06 25.5 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAJ24987.1 - 0.017 15.1 0.7 0.04 13.9 0.5 1.8 1 1 0 1 1 1 0 NADH(P)-binding FAM165 PF14981.1 OAJ24987.1 - 0.022 14.2 0.4 0.041 13.3 0.2 1.4 1 0 0 1 1 1 0 FAM165 family 3HCDH_N PF02737.13 OAJ24987.1 - 0.03 13.9 0.1 0.044 13.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TFIIB PF00382.14 OAJ24987.1 - 0.033 13.9 0.1 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Shikimate_DH PF01488.15 OAJ24987.1 - 0.042 13.9 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 OAJ24987.1 - 0.049 12.7 0.1 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IclR PF01614.13 OAJ24987.1 - 0.086 12.5 0.9 0.19 11.4 0.2 1.8 2 0 0 2 2 2 0 Bacterial transcriptional regulator Epimerase PF01370.16 OAJ24987.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 OAJ24988.1 - 3.2e-10 39.2 15.9 3.2e-10 39.2 11.0 3.2 1 1 0 2 2 2 1 Major Facilitator Superfamily PSRT PF07636.6 OAJ24988.1 - 0.11 11.9 5.1 0.31 10.5 3.5 1.7 1 0 0 1 1 1 0 PSRT PHD PF00628.24 OAJ24990.1 - 2.1e-08 33.7 8.4 2.1e-08 33.7 5.8 1.9 2 0 0 2 2 2 1 PHD-finger Retrotrans_gag PF03732.12 OAJ24992.1 - 0.06 13.4 0.5 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein DUF3940 PF13076.1 OAJ24992.1 - 0.11 12.1 0.8 0.27 10.8 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3940) DUF377 PF04041.8 OAJ24994.1 - 0.0046 15.7 0.0 0.0076 15.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF377) DUF4449 PF14613.1 OAJ24994.1 - 0.023 14.6 0.7 0.066 13.1 0.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4449) Cofilin_ADF PF00241.15 OAJ24995.1 - 3.1e-10 40.0 0.0 3.4e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein IBR PF01485.16 OAJ24996.1 - 1.2e-20 73.1 45.8 2.5e-12 46.4 4.8 4.5 3 1 1 4 4 4 2 IBR domain zf-C3HC4 PF00097.20 OAJ24996.1 - 0.00036 20.1 5.8 0.00036 20.1 4.0 4.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ24996.1 - 0.0014 18.4 5.6 0.0014 18.4 3.9 3.8 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ24996.1 - 0.0014 18.6 5.1 0.0014 18.6 3.5 4.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 OAJ24996.1 - 1.3 8.6 33.4 1.1 8.8 3.3 4.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 OAJ24996.1 - 8.5 6.3 29.7 0.2 11.5 0.6 4.6 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING RRM_1 PF00076.17 OAJ24997.1 - 3.3e-15 55.4 0.0 4.9e-07 29.2 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ24997.1 - 1.7e-12 47.1 0.0 1.2e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ24997.1 - 7e-05 22.6 0.0 0.0055 16.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAF PF02969.12 OAJ24998.1 - 1.4e-21 76.2 0.0 3.6e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 OAJ24998.1 - 7.1e-13 48.4 0.3 1.1e-11 44.6 0.2 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1546) Histone PF00125.19 OAJ24998.1 - 7.2e-06 26.0 0.5 1.8e-05 24.7 0.3 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF4611 PF15387.1 OAJ24998.1 - 0.013 15.6 0.3 0.85 9.8 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) TFIID-31kDa PF02291.10 OAJ24998.1 - 0.098 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit MSP1_C PF07462.6 OAJ24998.1 - 0.17 10.2 1.1 0.29 9.4 0.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus WD40 PF00400.27 OAJ24999.1 - 1.2e-19 69.3 6.4 6.6e-05 22.6 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 OAJ24999.1 - 0.011 13.8 2.4 0.42 8.6 0.4 2.9 2 1 0 2 2 2 0 Nucleoporin Nup120/160 DUF1241 PF06840.6 OAJ24999.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) zf-RING_2 PF13639.1 OAJ25000.1 - 3.9e-08 33.0 13.4 6.1e-08 32.3 9.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ25000.1 - 4.8e-07 29.7 15.1 7.7e-07 29.0 10.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ25000.1 - 2.1e-06 27.2 13.0 3.5e-06 26.5 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ25000.1 - 7.1e-06 25.6 10.7 1.3e-05 24.8 7.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAJ25000.1 - 1.3e-05 24.7 14.3 2e-05 24.1 9.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAJ25000.1 - 0.0023 17.7 13.0 0.0044 16.8 9.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING TMF_DNA_bd PF12329.3 OAJ25000.1 - 0.014 15.1 1.0 0.028 14.2 0.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.3 OAJ25000.1 - 0.04 13.1 0.3 0.067 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-rbx1 PF12678.2 OAJ25000.1 - 0.04 14.0 11.5 0.082 13.0 7.9 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger YlqD PF11068.3 OAJ25000.1 - 0.078 13.0 1.4 0.14 12.1 1.0 1.4 1 0 0 1 1 1 0 YlqD protein DUF4407 PF14362.1 OAJ25000.1 - 0.3 10.0 1.3 0.67 8.8 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-RING_6 PF14835.1 OAJ25000.1 - 1.2 8.9 9.3 2 8.2 6.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF812 PF05667.6 OAJ25000.1 - 3.2 6.1 8.8 0.42 9.0 3.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) zf-RING_4 PF14570.1 OAJ25000.1 - 6.1 6.5 12.2 10 5.7 8.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ras PF00071.17 OAJ25001.1 - 9.9e-65 216.8 0.8 1.2e-64 216.6 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ25001.1 - 6.9e-21 74.9 0.0 9.9e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ25001.1 - 1.9e-17 63.0 0.1 2.4e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ25001.1 - 2.6e-07 30.0 0.1 3e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 OAJ25001.1 - 2.7e-06 26.9 0.2 5e-06 26.0 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ25001.1 - 4.1e-05 23.5 0.0 6.6e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 OAJ25001.1 - 7.7e-05 21.9 0.1 9.3e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 OAJ25001.1 - 0.00089 19.3 0.0 0.0016 18.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 OAJ25001.1 - 0.0019 17.5 0.1 0.016 14.5 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.24 OAJ25001.1 - 0.0056 16.8 0.1 0.35 11.0 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ25001.1 - 0.016 15.2 0.2 0.047 13.6 0.1 2.0 1 1 1 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 OAJ25001.1 - 0.016 14.4 0.1 0.047 12.8 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 OAJ25001.1 - 0.036 13.8 0.0 0.088 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 OAJ25001.1 - 0.036 13.5 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 OAJ25001.1 - 0.074 12.5 0.0 1.2 8.6 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NAGLU PF05089.7 OAJ25001.1 - 0.092 11.4 0.0 0.16 10.6 0.0 1.5 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain G-alpha PF00503.15 OAJ25001.1 - 1.1 7.8 5.1 13 4.3 0.7 2.9 1 1 1 2 2 2 0 G-protein alpha subunit COG4 PF08318.7 OAJ25002.1 - 1.5e-44 152.1 0.0 4.8e-26 91.3 0.0 2.2 2 0 0 2 2 2 2 COG4 transport protein CK2S PF15011.1 OAJ25002.1 - 0.016 15.0 3.0 0.45 10.2 0.3 3.0 3 1 0 3 3 3 0 Casein Kinase 2 substrate Pex14_N PF04695.8 OAJ25004.1 - 2.9 7.9 11.4 3.6 7.6 2.8 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_60s PF00428.14 OAJ25005.1 - 0.006 16.9 2.9 0.013 15.9 2.0 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein BSP_II PF05432.6 OAJ25005.1 - 0.056 12.7 6.1 0.069 12.4 4.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 OAJ25005.1 - 0.58 9.2 5.4 0.76 8.8 3.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PBP1_TM PF14812.1 OAJ25005.1 - 2.5 8.4 9.5 1 9.7 2.9 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3381 PF11861.3 OAJ25005.1 - 4.3 6.8 8.5 0.25 10.8 2.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Pro_isomerase PF00160.16 OAJ25007.1 - 5e-47 159.9 0.1 2e-46 158.0 0.0 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 OAJ25007.1 - 6e-12 44.9 2.9 0.0011 18.7 0.0 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat Prefoldin_2 PF01920.15 OAJ25008.1 - 3.8e-17 61.9 7.7 4.9e-17 61.6 5.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.2 OAJ25008.1 - 0.027 14.2 2.2 0.027 14.2 1.6 2.1 2 0 0 2 2 2 0 Tropomyosin like RasGAP_C PF03836.10 OAJ25008.1 - 0.045 13.4 0.7 0.045 13.4 0.5 2.7 2 1 1 3 3 3 0 RasGAP C-terminus Snapin_Pallidin PF14712.1 OAJ25008.1 - 0.093 13.0 1.0 0.093 13.0 0.7 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Sec23_trunk PF04811.10 OAJ25008.1 - 0.11 11.8 1.3 0.23 10.7 0.9 1.5 1 1 0 1 1 1 0 Sec23/Sec24 trunk domain Antimicrobial_3 PF08025.6 OAJ25008.1 - 0.27 10.9 1.3 0.7 9.6 0.9 1.7 1 0 0 1 1 1 0 Spider antimicrobial peptide Init_tRNA_PT PF04179.7 OAJ25008.1 - 0.85 8.4 4.7 0.89 8.3 3.3 1.0 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase NPV_P10 PF05531.7 OAJ25008.1 - 1.2 9.4 3.8 1.5 9.0 0.1 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cortex-I_coil PF09304.5 OAJ25008.1 - 1.5 8.9 7.9 0.62 10.1 0.6 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil ADIP PF11559.3 OAJ25008.1 - 2.4 8.0 10.5 4.5 7.1 1.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.6 OAJ25008.1 - 3.2 7.4 8.7 17 5.1 1.5 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CCDC144C PF14915.1 OAJ25008.1 - 3.3 6.5 12.5 21 3.9 8.6 1.9 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region DUF4140 PF13600.1 OAJ25008.1 - 3.4 8.1 6.0 18 5.8 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cyt-b5 PF00173.23 OAJ25012.1 - 4.7e-09 35.9 0.1 7.4e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Fungal_trans PF04082.13 OAJ25013.1 - 2.2e-23 82.4 0.0 8.8e-23 80.4 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Activator_LAG-3 PF11498.3 OAJ25013.1 - 0.72 8.5 30.6 0.14 10.8 13.5 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF3712 PF12505.3 OAJ25016.1 - 3.3e-109 359.9 48.9 5.7e-23 81.2 0.0 10.3 11 0 0 11 11 11 7 Protein of unknown function (DUF3712) LEA_2 PF03168.8 OAJ25016.1 - 3.3e-06 27.3 21.3 0.19 12.1 0.0 9.0 9 0 0 9 9 9 3 Late embryogenesis abundant protein Bactofilin PF04519.8 OAJ25016.1 - 0.063 13.2 0.1 0.39 10.7 0.0 2.5 2 0 0 2 2 2 0 Polymer-forming cytoskeletal LON PF02190.11 OAJ25017.1 - 1.5e-24 86.8 0.0 1.9e-23 83.2 0.0 2.1 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 OAJ25017.1 - 1.5e-12 47.3 21.6 3.7e-07 30.0 6.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ25017.1 - 3e-11 42.9 19.6 6.7e-07 29.0 7.0 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_4 PF15227.1 OAJ25017.1 - 1.2e-09 37.8 21.6 8.4e-06 25.5 3.0 2.5 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 OAJ25017.1 - 2.8e-09 36.4 17.1 5.2e-06 26.0 3.6 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ25017.1 - 3.8e-09 36.0 21.1 4.9e-05 22.9 5.8 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ25017.1 - 4.3e-09 35.9 19.3 2.1e-05 24.1 5.6 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_6 PF14835.1 OAJ25017.1 - 0.00015 21.4 11.6 0.035 13.8 1.2 2.5 2 0 0 2 2 2 2 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 OAJ25017.1 - 0.0021 17.6 3.6 0.0021 17.6 2.5 3.0 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 OAJ25017.1 - 0.0029 17.2 16.9 0.075 12.7 3.0 2.6 2 0 0 2 2 2 2 RING-type zinc-finger Prok-RING_4 PF14447.1 OAJ25017.1 - 0.13 11.8 13.6 0.32 10.5 4.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 CLTH PF10607.4 OAJ25018.1 - 1.2e-17 63.9 0.0 5.7e-17 61.7 0.0 1.9 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Gly_kinase PF02595.10 OAJ25018.1 - 0.014 14.1 0.5 0.047 12.3 0.0 1.9 2 0 0 2 2 2 0 Glycerate kinase family EF1_GNE PF00736.14 OAJ25019.1 - 1.8e-29 101.2 2.2 3.2e-29 100.4 1.5 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 OAJ25019.1 - 6.6e-11 42.1 6.6 6.6e-11 42.1 4.5 2.6 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 OAJ25019.1 - 3e-05 24.4 0.0 6.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ25019.1 - 0.00011 22.0 0.3 0.0012 18.6 0.2 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAJ25019.1 - 0.0013 18.6 0.3 0.004 17.1 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.7 OAJ25019.1 - 0.015 15.0 2.6 0.021 14.5 1.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 OAJ25019.1 - 0.31 10.4 5.5 0.39 10.1 3.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4355 PF14265.1 OAJ25020.1 - 0.88 9.5 19.3 3 7.8 13.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) PBP1_TM PF14812.1 OAJ25020.1 - 2.2 8.6 8.0 15 5.9 0.0 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_23 PF13476.1 OAJ25020.1 - 3.2 8.0 9.1 5 7.4 6.3 1.3 1 0 0 1 1 1 0 AAA domain DS PF01916.12 OAJ25022.1 - 4.4e-133 443.0 0.0 6.6e-133 442.4 0.0 1.2 1 0 0 1 1 1 1 Deoxyhypusine synthase AAA PF00004.24 OAJ25022.1 - 1.3e-57 193.7 0.0 5e-45 152.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ25022.1 - 2.2e-07 31.0 5.8 0.014 15.4 0.1 4.2 3 1 1 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 OAJ25022.1 - 2.6e-07 31.4 0.0 0.011 16.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 OAJ25022.1 - 9.4e-06 25.5 0.0 0.096 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 OAJ25022.1 - 3.8e-05 23.4 0.0 0.024 14.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 OAJ25022.1 - 0.0001 21.8 0.3 0.0067 15.8 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ25022.1 - 0.00011 21.9 0.0 0.0089 15.7 0.0 3.2 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 OAJ25022.1 - 0.00013 22.0 0.1 0.008 16.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 OAJ25022.1 - 0.00046 20.4 0.0 0.21 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAJ25022.1 - 0.00071 19.4 0.0 0.27 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 OAJ25022.1 - 0.0011 18.1 0.0 0.0073 15.3 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 OAJ25022.1 - 0.0019 17.6 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 OAJ25022.1 - 0.0021 18.0 0.0 0.25 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 OAJ25022.1 - 0.0022 18.0 0.0 3.7 7.5 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 OAJ25022.1 - 0.0025 17.2 0.0 2.1 7.7 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.8 OAJ25022.1 - 0.0036 16.2 0.0 2.2 7.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) KaiC PF06745.8 OAJ25022.1 - 0.0037 16.4 0.2 0.0077 15.3 0.0 1.5 2 0 0 2 2 1 1 KaiC TIP49 PF06068.8 OAJ25022.1 - 0.0049 15.6 0.0 0.041 12.5 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_2 PF07724.9 OAJ25022.1 - 0.0089 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Parvo_NS1 PF01057.12 OAJ25022.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.16 OAJ25022.1 - 0.014 14.6 0.3 0.061 12.4 0.1 2.2 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 OAJ25022.1 - 0.016 14.8 1.0 4 7.0 0.0 3.2 4 0 0 4 4 3 0 NACHT domain RNA_helicase PF00910.17 OAJ25022.1 - 0.031 14.4 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.11 OAJ25022.1 - 0.05 12.8 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 OAJ25022.1 - 0.069 12.7 0.2 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 OAJ25022.1 - 0.07 12.7 0.0 0.71 9.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 OAJ25022.1 - 0.12 12.2 0.1 10 5.9 0.0 2.6 3 0 0 3 3 2 0 Shikimate kinase UPF0079 PF02367.12 OAJ25022.1 - 0.13 11.9 0.1 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 OAJ25022.1 - 0.25 10.1 0.0 3.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 OAJ25022.1 - 0.36 9.6 0.0 1.9 7.3 0.0 2.0 3 0 0 3 3 2 0 NB-ARC domain NTPase_1 PF03266.10 OAJ25022.1 - 0.43 10.2 0.0 6.2 6.5 0.0 2.2 2 0 0 2 2 2 0 NTPase adh_short PF00106.20 OAJ25023.1 - 0.02 14.7 0.1 0.03 14.2 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Serglycin PF04360.7 OAJ25023.1 - 0.13 11.9 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Serglycin Cupin_8 PF13621.1 OAJ25024.1 - 1.6e-49 168.7 0.0 2e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 OAJ25024.1 - 0.013 14.9 0.0 5.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Cupin domain JmjC PF02373.17 OAJ25024.1 - 0.047 13.9 0.1 0.4 10.9 0.0 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase PI3_PI4_kinase PF00454.22 OAJ25025.1 - 3.7e-30 105.1 0.0 7.9e-30 104.0 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase adh_short PF00106.20 OAJ25026.1 - 4.1e-19 69.0 0.6 5.8e-19 68.6 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ25026.1 - 7.5e-11 42.0 0.2 1.1e-10 41.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAJ25026.1 - 1.5e-07 31.1 0.2 3.5e-07 29.8 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 OAJ25026.1 - 0.00011 22.0 0.1 0.00062 19.5 0.1 2.0 1 1 1 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 OAJ25026.1 - 0.00074 18.4 0.1 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 OAJ25026.1 - 0.0029 17.2 1.5 0.0099 15.5 0.2 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 OAJ25026.1 - 0.16 12.4 1.2 0.52 10.7 0.5 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF3712 PF12505.3 OAJ25027.1 - 1.1e-108 358.2 44.4 8.9e-23 80.6 0.1 8.4 8 0 0 8 8 8 6 Protein of unknown function (DUF3712) LEA_2 PF03168.8 OAJ25027.1 - 1.8e-10 41.1 17.1 0.046 14.0 0.1 9.3 10 0 0 10 10 10 4 Late embryogenesis abundant protein Kelch_4 PF13418.1 OAJ25028.1 - 1.2e-13 50.6 3.3 0.0019 17.9 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 OAJ25028.1 - 5.4e-12 45.3 2.1 0.097 12.8 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 OAJ25028.1 - 9e-09 35.2 6.6 0.00037 20.5 0.1 6.4 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 OAJ25028.1 - 1.2e-07 31.1 0.1 0.01 15.3 0.0 3.7 3 1 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 OAJ25028.1 - 1.2e-07 31.5 0.5 0.00016 21.5 0.0 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 OAJ25028.1 - 0.00011 21.7 0.3 0.0096 15.6 0.0 3.6 2 0 0 2 2 2 1 Kelch motif LrgB PF04172.11 OAJ25033.1 - 1.4e-13 50.4 0.0 1.4e-13 50.4 0.0 2.1 2 1 1 3 3 3 1 LrgB-like family LrgA PF03788.9 OAJ25033.1 - 0.0087 15.7 0.2 0.0087 15.7 0.2 3.1 2 2 1 3 3 3 1 LrgA family Gp_dh_C PF02800.15 OAJ25035.1 - 8.9e-73 242.9 0.0 1.2e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 OAJ25035.1 - 4.2e-58 195.6 0.1 6.8e-58 194.9 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain G_glu_transpept PF01019.16 OAJ25036.1 - 1.3e-138 462.6 0.1 2.4e-119 399.1 0.0 2.1 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase Peroxidase_2 PF01328.12 OAJ25039.1 - 1.6e-20 73.0 0.4 3.3e-20 71.9 0.3 1.5 1 1 0 1 1 1 1 Peroxidase, family 2 SNF5 PF04855.7 OAJ25040.1 - 5.5e-69 232.3 1.7 5.5e-69 232.3 1.1 3.5 3 1 0 3 3 3 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 OAJ25040.1 - 0.0082 15.4 1.6 0.023 14.0 1.1 1.8 1 0 0 1 1 1 1 GATA zinc finger FYDLN_acid PF09538.5 OAJ25040.1 - 0.32 11.5 0.0 0.32 11.5 0.0 5.1 5 0 0 5 5 5 0 Protein of unknown function (FYDLN_acid) cwf18 PF08315.7 OAJ25042.1 - 7.2e-26 91.1 6.9 9.6e-26 90.7 4.8 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor SCP1201-deam PF14428.1 OAJ25042.1 - 0.13 11.9 0.2 0.29 10.8 0.0 1.7 2 1 0 2 2 2 0 SCP1.201-like deaminase RRM_1 PF00076.17 OAJ25043.1 - 7.8e-33 111.9 0.0 2.3e-17 62.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ25043.1 - 8.3e-22 76.9 0.0 9.5e-10 38.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ25043.1 - 1.7e-17 62.9 0.0 2.4e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 OAJ25043.1 - 0.067 12.7 0.2 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Ribonuclease B OB domain EF1G PF00647.14 OAJ25044.1 - 2.7e-46 155.6 0.2 4.8e-46 154.8 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 OAJ25044.1 - 3.5e-14 52.7 0.0 8.4e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ25044.1 - 2.3e-11 43.5 0.0 5.2e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ25044.1 - 3e-09 36.6 0.0 7.4e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAJ25044.1 - 4e-09 36.5 0.0 8.3e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 OAJ25044.1 - 3.5e-06 27.4 0.0 1.1e-05 25.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAJ25044.1 - 3.8e-06 26.8 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.14 OAJ25044.1 - 0.46 10.9 13.4 1.2 9.5 9.3 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein CPDase PF07823.6 OAJ25045.1 - 2.2e-29 102.3 0.0 2.4e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 OAJ25045.1 - 3.1e-05 23.7 0.1 0.0001 22.0 0.1 1.7 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily DUF3349 PF11829.3 OAJ25045.1 - 0.0069 16.7 0.0 0.018 15.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3349) RhoGEF PF00621.15 OAJ25046.1 - 3.4e-40 137.8 0.2 5.6e-40 137.1 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 OAJ25046.1 - 5.5e-33 113.5 0.0 1e-32 112.7 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 OAJ25046.1 - 1.1e-20 73.4 0.2 2.9e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 CDC24 Calponin PB1 PF00564.19 OAJ25046.1 - 8.2e-10 38.2 0.1 1.6e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 OAJ25046.1 - 0.19 11.9 0.2 1.2 9.3 0.1 2.2 1 1 0 1 1 1 0 PH domain Glyco_hydro_25 PF01183.15 OAJ25047.1 - 1.4e-48 165.1 3.5 1.7e-48 164.8 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 RNA_pol PF00940.14 OAJ25049.1 - 3.2e-154 513.2 0.0 4.4e-154 512.8 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 OAJ25049.1 - 1e-70 238.5 0.7 1.7e-70 237.8 0.5 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Nop14 PF04147.7 OAJ25049.1 - 0.019 12.9 7.1 0.028 12.3 4.9 1.1 1 0 0 1 1 1 0 Nop14-like family HEAT PF02985.17 OAJ25050.1 - 2.3e-25 86.3 7.8 9.7e-05 22.1 0.0 11.1 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.1 OAJ25050.1 - 1.1e-19 70.3 6.0 1.4e-07 31.7 0.0 8.7 8 0 0 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.1 OAJ25050.1 - 1.5e-18 66.8 13.8 0.00042 20.5 0.0 6.9 3 2 5 8 8 8 6 HEAT repeats IBN_N PF03810.14 OAJ25050.1 - 6.6e-12 45.1 2.9 1.1e-09 38.0 0.1 3.8 3 1 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 OAJ25050.1 - 0.00047 20.0 0.7 0.083 12.8 0.2 3.7 2 1 0 2 2 2 1 Exportin 1-like protein Arm PF00514.18 OAJ25050.1 - 0.00051 19.7 11.4 0.028 14.2 0.1 5.5 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 OAJ25050.1 - 0.00052 20.3 0.2 0.55 10.6 0.1 4.9 5 1 2 7 7 7 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 OAJ25050.1 - 0.00065 18.1 2.1 1.1 7.5 0.1 3.5 2 2 1 3 3 3 2 Adaptin N terminal region TIP120 PF08623.5 OAJ25050.1 - 0.00082 18.9 0.2 4.4 6.8 0.0 4.1 3 1 1 4 4 4 1 TATA-binding protein interacting (TIP20) MMS19_N PF14500.1 OAJ25050.1 - 0.0021 17.3 0.1 0.018 14.2 0.1 2.2 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II CLASP_N PF12348.3 OAJ25050.1 - 0.028 13.8 0.3 3.2 7.0 0.0 3.7 3 1 1 4 4 4 0 CLASP N terminal Pex14_N PF04695.8 OAJ25051.1 - 1.2e-31 109.5 0.0 1.2e-31 109.5 0.0 3.8 2 1 0 3 3 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 OAJ25051.1 - 1.9e-06 27.6 3.5 3.4e-06 26.7 2.4 1.4 1 0 0 1 1 1 1 IncA protein NPV_P10 PF05531.7 OAJ25051.1 - 0.0003 20.9 5.7 0.027 14.6 0.3 3.0 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 OAJ25051.1 - 0.0012 18.5 2.9 0.0012 18.5 2.0 2.4 2 1 1 3 3 2 2 Laminin Domain II Atg14 PF10186.4 OAJ25051.1 - 0.0034 16.3 0.5 0.0049 15.8 0.3 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 OAJ25051.1 - 0.0042 15.6 1.9 0.0058 15.1 1.3 1.1 1 0 0 1 1 1 1 AAA domain MAD PF05557.8 OAJ25051.1 - 0.0055 14.8 4.1 0.01 13.9 2.9 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein EzrA PF06160.7 OAJ25051.1 - 0.0096 14.1 3.4 0.015 13.5 2.4 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA OmpH PF03938.9 OAJ25051.1 - 0.011 15.7 7.2 0.02 14.8 5.0 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PilJ PF13675.1 OAJ25051.1 - 0.011 16.0 7.5 0.053 13.8 3.2 2.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Baculo_PEP_C PF04513.7 OAJ25051.1 - 0.021 14.6 0.7 0.074 12.8 0.5 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 OAJ25051.1 - 0.025 11.9 10.0 0.033 11.5 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_I PF06008.9 OAJ25051.1 - 0.026 13.8 8.1 0.044 13.0 5.6 1.3 1 0 0 1 1 1 0 Laminin Domain I TBPIP PF07106.8 OAJ25051.1 - 0.032 13.7 4.9 0.033 13.7 1.2 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Sipho_Gp157 PF05565.6 OAJ25051.1 - 0.041 13.4 4.0 0.066 12.7 2.8 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 IFT57 PF10498.4 OAJ25051.1 - 0.059 12.1 6.4 0.019 13.6 1.9 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1395 PF07160.7 OAJ25051.1 - 0.073 12.5 4.8 0.13 11.7 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Spc7 PF08317.6 OAJ25051.1 - 0.075 11.6 4.9 0.17 10.4 3.4 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 OAJ25051.1 - 0.082 11.9 8.6 0.12 11.4 5.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2968 PF11180.3 OAJ25051.1 - 0.098 12.0 11.8 0.34 10.2 8.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) HALZ PF02183.13 OAJ25051.1 - 0.22 11.2 7.9 0.41 10.4 0.1 3.2 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF342 PF03961.8 OAJ25051.1 - 0.29 9.5 3.3 0.43 8.9 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2317 PF10079.4 OAJ25051.1 - 0.32 9.5 4.2 0.47 9.0 2.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Rep_4 PF05797.6 OAJ25051.1 - 0.35 9.5 2.8 0.48 9.0 2.0 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) FlgN PF05130.7 OAJ25051.1 - 0.37 11.0 10.9 0.63 10.2 7.6 1.3 1 0 0 1 1 1 0 FlgN protein Nup88 PF10168.4 OAJ25051.1 - 0.43 8.3 4.2 0.59 7.9 2.9 1.1 1 0 0 1 1 1 0 Nuclear pore component Occludin_ELL PF07303.8 OAJ25051.1 - 0.5 11.1 5.1 2.1 9.1 1.8 2.3 1 1 1 2 2 2 0 Occludin homology domain DUF1664 PF07889.7 OAJ25051.1 - 0.58 9.9 8.1 0.71 9.6 2.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMPIT PF07851.8 OAJ25051.1 - 0.87 8.5 3.5 1.2 8.1 2.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.1 OAJ25051.1 - 0.98 8.3 9.0 0.07 12.0 2.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.5 OAJ25051.1 - 1 9.5 3.7 1.9 8.6 1.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin PF00804.20 OAJ25051.1 - 1.1 9.4 8.5 36 4.5 5.9 2.4 1 1 0 1 1 1 0 Syntaxin DUF2408 PF10303.4 OAJ25051.1 - 1.5 8.9 5.0 11 6.1 3.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Spectrin PF00435.16 OAJ25051.1 - 1.6 9.0 7.6 0.66 10.2 1.7 2.2 1 1 1 2 2 2 0 Spectrin repeat BLOC1_2 PF10046.4 OAJ25051.1 - 1.7 8.8 6.3 3 8.0 1.3 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG2 PF06148.6 OAJ25051.1 - 1.8 8.4 6.5 25 4.7 4.5 2.2 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 ADIP PF11559.3 OAJ25051.1 - 1.9 8.3 9.2 0.5 10.2 2.9 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 OAJ25051.1 - 2.5 5.8 3.7 3.6 5.3 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 OAJ25051.1 - 3.4 8.0 7.4 5.9 7.2 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 OAJ25051.1 - 3.6 7.2 9.6 8.9 5.9 6.7 1.6 1 1 0 1 1 1 0 Mnd1 family V-SNARE PF05008.10 OAJ25051.1 - 5 7.3 9.8 7.6 6.7 5.3 2.2 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Med9 PF07544.8 OAJ25051.1 - 5.8 6.7 8.9 8.4 6.2 0.2 3.0 2 1 1 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.15 OAJ25051.1 - 7.1 6.4 11.2 12 5.6 4.1 2.9 1 1 2 3 3 3 0 Prefoldin subunit zf-primase PF09329.6 OAJ25053.1 - 1.7e-10 40.3 1.0 2.9e-10 39.5 0.7 1.4 1 0 0 1 1 1 1 Primase zinc finger Proteasome PF00227.21 OAJ25054.1 - 1.3e-32 112.6 0.0 1.7e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Abhydrolase_4 PF08386.5 OAJ25060.1 - 4.2e-14 52.2 0.0 1e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 OAJ25060.1 - 3.4e-11 43.1 0.1 1.3e-06 28.1 0.0 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ25060.1 - 9e-08 32.2 0.5 4.8e-07 29.8 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ25060.1 - 0.017 14.8 0.0 0.049 13.3 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family KilA-N PF04383.8 OAJ25062.1 - 0.0011 18.5 0.0 0.0026 17.3 0.0 1.6 1 1 0 1 1 1 1 KilA-N domain Bac_rhodopsin PF01036.13 OAJ25063.1 - 8.5e-51 172.3 20.5 1.1e-50 172.0 14.2 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 OAJ25063.1 - 0.4 10.0 9.7 1.2 8.5 1.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Arteri_Gl PF00951.13 OAJ25063.1 - 0.8 9.2 5.6 0.14 11.7 0.9 1.9 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein AgrB PF04647.10 OAJ25063.1 - 3.5 6.6 9.6 0.12 11.4 2.1 1.9 2 0 0 2 2 2 0 Accessory gene regulator B ABC2_membrane_3 PF12698.2 OAJ25063.1 - 4.2 6.3 17.1 4.3 6.2 0.9 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF3810 PF12725.2 OAJ25063.1 - 4.9 5.9 6.2 0.26 10.1 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF2754 PF10953.3 OAJ25063.1 - 8 6.6 7.9 8.8 6.4 4.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) zf-CCHC_3 PF13917.1 OAJ25064.1 - 1e-07 31.5 3.2 2.4e-07 30.3 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle CDC14 PF08045.6 OAJ25065.1 - 2e-10 40.2 0.7 3.5e-05 23.0 0.2 3.0 2 1 0 2 2 2 2 Cell division control protein 14, SIN component TPR_11 PF13414.1 OAJ25066.1 - 1.1e-10 40.9 0.9 1.3e-09 37.5 0.7 2.2 1 1 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 OAJ25066.1 - 4.7e-09 35.4 0.2 3.1e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ25066.1 - 9.8e-06 25.1 0.3 0.18 11.8 0.4 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 OAJ25066.1 - 0.0011 18.7 0.2 0.0052 16.6 0.1 2.3 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 OAJ25066.1 - 0.0018 18.1 0.5 0.28 11.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ25066.1 - 0.02 15.4 0.4 5.3 7.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 OAJ25066.1 - 0.043 13.9 1.0 0.19 11.8 0.6 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 OAJ25066.1 - 0.07 12.9 0.0 2.1 8.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DEAD PF00270.24 OAJ25067.1 - 1.8e-43 147.9 0.0 1.3e-42 145.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ25067.1 - 9e-27 92.7 0.1 1.7e-26 91.8 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 OAJ25067.1 - 0.0063 14.9 0.0 0.011 14.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) ResIII PF04851.10 OAJ25067.1 - 0.19 11.5 0.0 0.82 9.4 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Acyltransferase PF01553.16 OAJ25068.1 - 7.7e-15 54.5 0.0 2e-10 40.2 0.0 2.2 2 0 0 2 2 2 2 Acyltransferase MOSC PF03473.12 OAJ25069.1 - 2.1e-11 43.3 0.0 5.4e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.14 OAJ25069.1 - 2.1e-08 33.3 0.0 2.3e-06 26.6 0.0 3.5 3 1 0 3 3 3 1 Aminotransferase class-V MOSC_N PF03476.11 OAJ25069.1 - 3.8e-08 33.0 0.0 0.00023 20.8 0.0 2.7 2 0 0 2 2 2 2 MOSC N-terminal beta barrel domain AAA PF00004.24 OAJ25070.1 - 2e-27 95.9 0.0 2.3e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ25070.1 - 0.00045 20.3 0.1 0.004 17.2 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ25070.1 - 0.0021 17.7 0.1 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 OAJ25070.1 - 0.011 15.6 0.1 0.015 15.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 OAJ25070.1 - 0.013 15.0 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAJ25070.1 - 0.014 15.5 0.1 0.019 15.1 0.0 1.5 1 1 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 OAJ25070.1 - 0.015 16.0 0.0 0.018 15.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 OAJ25070.1 - 0.018 14.7 0.1 0.045 13.4 0.0 1.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 OAJ25070.1 - 0.02 14.0 0.0 0.041 13.0 0.0 1.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 OAJ25070.1 - 0.023 13.4 0.0 0.028 13.1 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus AAA_16 PF13191.1 OAJ25070.1 - 0.026 14.5 0.0 0.035 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 OAJ25070.1 - 0.033 13.8 0.0 0.093 12.3 0.0 1.7 1 1 1 2 2 2 0 NACHT domain Zot PF05707.7 OAJ25070.1 - 0.036 13.5 0.0 2.6 7.4 0.0 2.1 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_25 PF13481.1 OAJ25070.1 - 0.039 13.3 0.1 0.086 12.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 OAJ25070.1 - 0.046 13.1 0.0 0.08 12.3 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein DEAD PF00270.24 OAJ25070.1 - 0.089 12.2 0.0 11 5.4 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase SKN1 PF03935.10 OAJ25071.1 - 3.4e-175 582.9 1.8 4e-175 582.7 1.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Phage_integrase PF00589.17 OAJ25073.1 - 3.6e-05 23.5 0.0 7.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family GST_N PF02798.15 OAJ25074.1 - 1.2e-11 44.5 0.2 7.4e-11 42.0 0.0 2.3 2 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 OAJ25074.1 - 1.9e-10 40.8 0.0 3.4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ25074.1 - 4.6e-09 36.1 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAJ25074.1 - 7.2e-09 35.5 0.0 2.3e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAJ25074.1 - 5.1e-07 29.4 0.0 1.2e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ25074.1 - 2.7e-05 24.5 0.0 5.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TSSC4 PF15264.1 OAJ25074.1 - 0.091 13.2 0.1 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 Lysis_col PF02402.11 OAJ25075.1 - 0.079 12.5 0.2 3 7.5 0.0 2.6 2 0 0 2 2 2 0 Lysis protein FbpA PF05833.6 OAJ25076.1 - 0.0083 14.7 3.0 0.0096 14.5 2.1 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) PAT1 PF09770.4 OAJ25076.1 - 0.12 10.6 5.8 0.14 10.3 4.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RNF111_N PF15303.1 OAJ25076.1 - 0.12 11.8 11.9 0.51 9.8 8.2 1.8 1 1 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus NAM-associated PF14303.1 OAJ25076.1 - 0.32 11.2 17.8 0.66 10.2 12.3 1.7 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Nop53 PF07767.6 OAJ25076.1 - 0.35 9.8 12.4 0.48 9.3 8.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) rRNA_processing PF08524.6 OAJ25076.1 - 9.8 5.9 13.2 49 3.6 9.2 2.1 1 1 1 2 2 2 0 rRNA processing DDE_Tnp_4 PF13359.1 OAJ25077.1 - 6.7e-18 64.7 0.0 1.4e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease ATG22 PF11700.3 OAJ25078.1 - 3.8e-114 381.7 23.9 4.5e-114 381.5 16.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 OAJ25078.1 - 8.6e-07 27.9 36.1 0.0054 15.5 2.5 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Methyltransf_33 PF10017.4 OAJ25080.1 - 6.1e-27 94.0 0.0 1.7e-26 92.5 0.0 1.8 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 OAJ25080.1 - 2.1e-17 63.3 1.7 3.7e-17 62.5 0.1 2.0 2 0 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 OAJ25080.1 - 1e-05 25.8 2.6 2e-05 24.9 0.9 2.3 2 0 0 2 2 2 1 DinB superfamily DUF2076 PF09849.4 OAJ25081.1 - 8e-10 39.1 13.0 9.4e-10 38.9 9.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 OAJ25081.1 - 0.0078 16.1 4.9 0.014 15.3 3.4 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 OAJ25081.1 - 0.28 10.9 2.2 12 5.7 0.1 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like TFIIA PF03153.8 OAJ25081.1 - 5.6 6.7 7.2 6.5 6.5 5.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aa_trans PF01490.13 OAJ25082.1 - 5.3e-82 275.4 32.3 6.5e-82 275.1 22.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2890 PF11081.3 OAJ25082.1 - 0.14 12.2 3.4 0.21 11.6 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nucleoplasmin PF03066.10 OAJ25082.1 - 0.55 9.7 5.4 0.9 9.0 3.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 OAJ25082.1 - 1.4 8.4 5.2 2.2 7.8 3.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.7 OAJ25082.1 - 2 8.0 7.4 2.8 7.5 5.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 OAJ25082.1 - 2 6.2 4.1 2.6 5.8 2.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 OAJ25082.1 - 4.2 5.2 5.3 6.8 4.5 3.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Retinal PF15449.1 OAJ25082.1 - 4.6 4.7 6.7 6 4.3 4.7 1.0 1 0 0 1 1 1 0 Retinal protein CAAD PF14159.1 OAJ25082.1 - 4.6 6.9 7.2 1.9 8.2 1.1 3.1 2 1 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Pkinase PF00069.20 OAJ25085.1 - 4.6e-66 222.6 0.0 4.6e-66 222.6 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ25085.1 - 6.2e-43 146.7 0.0 6.2e-43 146.7 0.0 1.8 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ25085.1 - 2.7e-07 29.8 0.0 1.8e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Spore_coat_CotO PF14153.1 OAJ25085.1 - 0.015 14.7 15.7 0.12 11.8 3.0 2.4 2 0 0 2 2 2 0 Spore coat protein CotO zf-DHHC PF01529.15 OAJ25085.1 - 0.11 11.9 1.2 1 8.6 0.1 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Ycf1 PF05758.7 OAJ25085.1 - 0.38 8.4 3.3 1.4 6.5 0.1 2.0 2 0 0 2 2 2 0 Ycf1 Seadorna_VP7 PF07387.6 OAJ25085.1 - 2.1 7.0 0.0 3.3 6.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Vps39_2 PF10367.4 OAJ25086.1 - 9.1e-07 29.0 1.2 2.1e-06 27.8 0.8 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 OAJ25086.1 - 1.1e-06 28.3 0.0 4.3e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 CNH domain Vps39_1 PF10366.4 OAJ25086.1 - 0.023 14.7 0.0 0.072 13.1 0.0 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 TPR_14 PF13428.1 OAJ25086.1 - 0.066 13.8 10.5 34 5.4 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat HAD PF12710.2 OAJ25087.1 - 3.4e-13 50.2 0.0 4.4e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 OAJ25087.1 - 1.2e-06 28.0 0.0 6.7e-06 25.6 0.0 1.9 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.7 OAJ25087.1 - 0.00013 21.1 0.4 0.0012 18.0 0.1 2.0 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.21 OAJ25087.1 - 0.00091 19.6 0.6 0.0044 17.4 0.0 2.1 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 OAJ25087.1 - 0.0011 19.2 0.1 0.0085 16.3 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Metallophos PF00149.23 OAJ25088.1 - 7.5e-43 146.2 0.9 9.5e-43 145.9 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PLA2_B PF01735.13 OAJ25089.1 - 7.4e-138 459.7 1.4 8.8e-138 459.5 1.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain XPG_N PF00752.12 OAJ25090.1 - 5.5e-30 103.6 0.0 1.1e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 OAJ25090.1 - 1e-26 92.7 0.0 2.4e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 XPG I-region NDUF_B8 PF05821.6 OAJ25091.1 - 1.5e-09 37.7 0.0 2.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Cnd2 PF05786.9 OAJ25093.1 - 2e-133 446.4 19.0 1e-80 272.2 1.1 4.2 4 0 0 4 4 4 3 Condensin complex subunit 2 DUF4152 PF13680.1 OAJ25093.1 - 0.00085 18.4 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4152) GCFC PF07842.7 OAJ25094.1 - 1.9e-68 230.8 14.4 2.6e-68 230.3 10.0 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 OAJ25094.1 - 1.7e-08 34.1 0.3 1.7e-08 34.1 0.2 2.7 3 0 0 3 3 3 1 G-patch domain p450 PF00067.17 OAJ25095.1 - 1.8e-49 168.5 0.0 3.7e-48 164.1 0.0 2.8 1 1 0 1 1 1 1 Cytochrome P450 TatD_DNase PF01026.16 OAJ25096.1 - 4.2e-49 167.0 0.0 6.4e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DUF1700 PF08006.6 OAJ25097.1 - 7.1 5.8 6.5 10 5.3 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Fer2_4 PF13510.1 OAJ25098.1 - 1.5e-18 66.3 0.1 4.5e-18 64.8 0.1 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 OAJ25098.1 - 1.9e-16 58.9 0.0 4.8e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region WD40 PF00400.27 OAJ25098.1 - 3.3e-15 55.2 1.6 8.6e-06 25.4 0.1 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Fer2 PF00111.22 OAJ25098.1 - 3.3e-08 33.1 1.5 5.2e-08 32.5 0.2 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Molybdopterin PF00384.17 OAJ25098.1 - 0.00052 18.8 0.0 0.00079 18.2 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fer4_15 PF13459.1 OAJ25098.1 - 0.055 14.0 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 4Fe-4S single cluster domain His_Phos_1 PF00300.17 OAJ25099.1 - 4.7e-14 52.7 0.0 2.5e-12 47.1 0.0 2.7 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Pol_alpha_B_N PF08418.5 OAJ25099.1 - 0.13 11.7 4.4 0.28 10.6 3.0 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal FDF PF09532.5 OAJ25100.1 - 3.2e-08 34.0 0.0 3.2e-08 34.0 0.0 3.4 5 0 0 5 5 5 1 FDF domain SM-ATX PF14438.1 OAJ25100.1 - 0.079 12.8 0.0 0.51 10.3 0.0 2.4 2 0 0 2 2 2 0 Ataxin 2 SM domain Molybdopterin PF00384.17 OAJ25101.1 - 4.1e-72 243.2 0.0 1.4e-36 126.2 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase DUF1982 PF09326.6 OAJ25101.1 - 2.1e-13 50.1 0.0 5.8e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) TPP_enzyme_M PF00205.17 OAJ25101.1 - 0.0045 16.7 0.0 1.3 8.7 0.0 2.8 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DNA_pol_E_B PF04042.11 OAJ25102.1 - 6.4e-46 156.2 0.2 8.8e-46 155.7 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_2 PF12850.2 OAJ25102.1 - 0.0025 17.6 0.0 0.032 14.0 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FleQ PF06490.6 OAJ25102.1 - 0.096 12.8 0.0 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ Zn_clus PF00172.13 OAJ25103.1 - 1.1e-11 44.4 7.1 1.8e-11 43.7 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-C_C PF11699.3 OAJ25109.1 - 3.3e-28 97.5 0.4 5.8e-28 96.7 0.2 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 OAJ25109.1 - 0.00024 20.5 0.0 0.0005 19.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Sirohm_synth_M PF14824.1 OAJ25109.1 - 0.028 13.3 0.6 3.2 6.7 0.2 2.5 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central AraC_binding PF02311.14 OAJ25109.1 - 0.2 11.3 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain Exo_endo_phos_2 PF14529.1 OAJ25111.1 - 2.2e-07 30.4 0.0 4.6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 OAJ25112.1 - 9e-24 84.0 0.0 1.2e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribonuclease PF00545.15 OAJ25113.1 - 1e-15 57.5 0.8 1.4e-15 57.0 0.6 1.3 1 1 0 1 1 1 1 ribonuclease UPF1_Zn_bind PF09416.5 OAJ25114.1 - 6.7e-74 246.5 8.6 6.2e-73 243.4 5.5 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 OAJ25114.1 - 1.1e-58 197.8 0.0 3.2e-58 196.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 OAJ25114.1 - 7e-56 189.4 1.4 1e-55 188.8 1.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ25114.1 - 1.4e-12 47.1 0.3 4.9e-12 45.4 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 OAJ25114.1 - 2.1e-11 43.7 0.0 2.9e-10 40.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 OAJ25114.1 - 2.2e-07 30.8 0.0 5.3e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 OAJ25114.1 - 1.6e-05 24.5 0.9 0.24 10.8 0.0 3.4 2 1 2 4 4 4 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 OAJ25114.1 - 4.9e-05 22.4 0.3 0.00075 18.5 0.0 2.6 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 OAJ25114.1 - 0.00027 20.6 0.1 0.001 18.7 0.1 2.0 1 1 0 1 1 1 1 Helicase SRP54 PF00448.17 OAJ25114.1 - 0.016 14.6 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PIF1 PF05970.9 OAJ25114.1 - 0.018 13.9 0.1 0.96 8.3 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_10 PF12846.2 OAJ25114.1 - 0.049 13.0 0.0 0.086 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 OAJ25114.1 - 0.05 13.7 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 OAJ25114.1 - 0.054 12.9 0.3 0.13 11.7 0.2 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase KaiC PF06745.8 OAJ25114.1 - 0.069 12.2 0.0 0.23 10.5 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA PF00004.24 OAJ25114.1 - 0.097 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 OAJ25114.1 - 0.13 11.4 0.0 0.31 10.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Herpes_gE PF02480.11 OAJ25115.1 - 9.3 4.3 7.8 35 2.4 0.1 1.8 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E RasGEF PF00617.14 OAJ25119.1 - 4.3e-42 143.9 0.0 7.5e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 OAJ25119.1 - 4.1e-10 39.7 1.9 4.2e-10 39.6 0.3 1.8 2 0 0 2 2 2 1 RasGEF N-terminal motif Acyl-CoA_dh_2 PF08028.6 OAJ25120.1 - 1.2e-14 54.6 0.1 2.2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAJ25120.1 - 4.4e-06 27.2 0.1 1e-05 26.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 OAJ25120.1 - 0.0025 17.9 1.2 0.0079 16.3 0.1 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain ADH_N PF08240.7 OAJ25121.1 - 2e-07 30.7 0.0 3.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ25121.1 - 7.2e-07 28.8 0.0 3e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ApbA PF02558.11 OAJ25121.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 OAJ25122.1 - 1.1e-24 87.2 3.0 2.2e-24 86.2 2.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ25122.1 - 1.8e-11 44.0 0.8 3.4e-11 43.1 0.5 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ25122.1 - 6.4e-11 42.4 0.0 7.6e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Bac_luciferase PF00296.15 OAJ25124.1 - 2 7.4 9.3 1.4 7.9 2.9 2.1 2 0 0 2 2 2 0 Luciferase-like monooxygenase Med15 PF09606.5 OAJ25125.1 - 0.2 9.8 31.4 0.37 8.9 21.6 1.3 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Gly_transf_sug PF04488.10 OAJ25126.1 - 2e-19 69.9 0.1 3.2e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 OAJ25126.1 - 0.00099 17.7 2.1 0.21 10.0 0.5 2.9 3 0 0 3 3 3 3 TcdA/TcdB catalytic glycosyltransferase domain SusD-like_2 PF12771.2 OAJ25126.1 - 0.084 11.2 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Starch-binding associating with outer membrane DSS1_SEM1 PF05160.8 OAJ25127.1 - 4.4e-19 68.0 8.5 3.7e-12 45.8 2.2 2.2 2 0 0 2 2 2 2 DSS1/SEM1 family Stm1_N PF09598.5 OAJ25127.1 - 5.4 7.7 8.9 1.3 9.7 0.1 2.9 3 0 0 3 3 3 0 Stm1 SWIRM PF04433.12 OAJ25128.1 - 2e-16 59.8 0.0 7.9e-16 57.9 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 OAJ25128.1 - 3.3e-10 39.8 0.0 1.1e-09 38.1 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 OAJ25128.1 - 2e-09 36.8 7.2 3.4e-09 36.0 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 OAJ25128.1 - 3.2e-06 27.1 0.0 1e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain RNA_pol_Rpb4 PF03874.11 OAJ25128.1 - 0.14 12.1 0.5 0.3 11.0 0.4 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb4 SAM_decarbox PF01536.11 OAJ25131.1 - 1.7e-78 263.5 0.0 3.2e-77 259.4 0.0 2.6 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase LSM PF01423.17 OAJ25132.1 - 4e-17 61.5 0.1 5.6e-17 61.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain 60KD_IMP PF02096.15 OAJ25133.1 - 4.6e-16 59.0 0.0 1.6e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 60Kd inner membrane protein Peptidase_S10 PF00450.17 OAJ25138.1 - 1.9e-73 248.0 0.0 2.5e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 OAJ25138.1 - 0.015 15.1 0.0 0.049 13.5 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S10 PF00450.17 OAJ25140.1 - 2.4e-76 257.5 0.1 3.3e-76 257.1 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PLU-1 PF08429.6 OAJ25141.1 - 1.1e-46 159.3 1.8 1.8e-46 158.5 1.2 1.4 1 0 0 1 1 1 1 PLU-1-like protein JmjC PF02373.17 OAJ25141.1 - 6.8e-42 142.3 0.4 1.3e-41 141.3 0.3 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 OAJ25141.1 - 3.9e-22 77.6 45.1 2.4e-12 46.3 2.3 4.5 4 0 0 4 4 4 3 PHD-finger ARID PF01388.16 OAJ25141.1 - 1.4e-20 72.9 0.0 2.8e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 OAJ25141.1 - 2.3e-12 46.7 0.2 9.8e-12 44.7 0.2 2.2 1 0 0 1 1 1 1 C5HC2 zinc finger JmjN PF02375.12 OAJ25141.1 - 5e-12 45.1 0.9 1e-11 44.1 0.6 1.5 1 0 0 1 1 1 1 jmjN domain PHD_2 PF13831.1 OAJ25141.1 - 1.1 8.5 28.3 1.5 8.1 0.2 4.2 4 0 0 4 4 4 0 PHD-finger Prok-RING_1 PF14446.1 OAJ25141.1 - 1.8 8.3 22.5 2.7 7.7 0.4 3.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 TIM PF00121.13 OAJ25142.1 - 1.1e-92 309.4 0.4 1.3e-92 309.3 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 OAJ25142.1 - 0.0071 15.6 0.2 0.082 12.1 0.0 2.0 1 1 1 2 2 2 1 CutC family REV PF00424.13 OAJ25143.1 - 0.19 11.6 1.7 0.33 10.8 0.0 2.3 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) Mis12 PF05859.7 OAJ25144.1 - 6.7e-17 61.6 0.4 2.3e-16 59.8 0.3 1.9 1 1 0 1 1 1 1 Mis12 protein Cyclin_N PF00134.18 OAJ25145.1 - 2.6e-10 39.9 0.1 7.5e-08 32.0 0.0 2.8 4 0 0 4 4 4 2 Cyclin, N-terminal domain RecO_C PF02565.10 OAJ25145.1 - 0.12 12.2 0.3 2.9 7.7 0.0 2.4 2 1 0 2 2 2 0 Recombination protein O C terminal Pyr_redox_2 PF07992.9 OAJ25146.1 - 0.0072 16.2 0.0 0.0084 16.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_5 PF12695.2 OAJ25146.1 - 0.014 15.1 0.6 0.02 14.6 0.4 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family CW_binding_2 PF04122.7 OAJ25146.1 - 0.037 14.2 0.1 0.085 13.0 0.1 1.5 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 DUF1188 PF06690.6 OAJ25146.1 - 0.071 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) KAR9 PF08580.5 OAJ25146.1 - 0.22 9.7 3.9 0.19 9.9 2.7 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 TauE PF01925.14 OAJ25146.1 - 1.7 8.0 7.6 0.098 12.0 1.4 1.6 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE SOG2 PF10428.4 OAJ25146.1 - 9.5 4.7 12.5 13 4.2 8.7 1.3 1 1 0 1 1 1 0 RAM signalling pathway protein Myb_DNA-binding PF00249.26 OAJ25147.1 - 5.3e-14 52.0 0.0 6.9e-06 26.0 0.0 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ25147.1 - 4.2e-11 42.7 0.0 5.2e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Nop16 PF09420.5 OAJ25147.1 - 0.076 13.1 0.0 12 5.9 0.0 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 Phos_pyr_kin PF08543.7 OAJ25148.1 - 5.5e-09 35.5 0.0 1.3e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 OAJ25148.1 - 1.5e-07 30.8 0.1 4.3e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 pfkB family carbohydrate kinase OrfB_Zn_ribbon PF07282.6 OAJ25149.1 - 4.2e-13 48.7 0.1 8.8e-13 47.7 0.1 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.3 OAJ25149.1 - 4.2e-09 35.5 0.3 1e-08 34.3 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_IS605 PF01385.14 OAJ25149.1 - 1.2e-07 31.3 0.0 2.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Probable transposase Chorismate_synt PF01264.16 OAJ25150.1 - 0.00075 18.0 0.0 0.0016 17.0 0.0 1.5 1 1 0 1 1 1 1 Chorismate synthase NAD_binding_2 PF03446.10 OAJ25151.1 - 1.2e-53 181.2 0.0 1.6e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 6PGD PF00393.14 OAJ25151.1 - 1.2e-50 172.3 0.1 1.6e-50 172.0 0.1 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain F420_oxidored PF03807.12 OAJ25151.1 - 0.0057 17.0 0.1 0.0093 16.3 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 OAJ25151.1 - 0.034 14.2 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OrfB_Zn_ribbon PF07282.6 OAJ25152.1 - 0.00013 21.6 1.6 0.0046 16.5 1.1 2.5 1 1 0 1 1 1 1 Putative transposase DNA-binding domain MIP PF00230.15 OAJ25155.1 - 4.1e-41 140.9 13.2 5.5e-41 140.5 9.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2160 PF09928.4 OAJ25155.1 - 0.12 12.4 3.0 0.26 11.3 2.1 1.6 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2160) Metallophos PF00149.23 OAJ25156.1 - 6.8e-44 149.6 0.0 1.9e-43 148.2 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF155 PF02582.9 OAJ25157.1 - 8.3e-48 162.5 0.0 1.2e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF2890 PF11081.3 OAJ25157.1 - 8.8 6.3 20.5 0.017 15.1 3.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Grp1_Fun34_YaaH PF01184.14 OAJ25158.1 - 3e-77 258.6 16.1 3.6e-77 258.4 11.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family 6PGD PF00393.14 OAJ25159.1 - 1.3e-13 50.8 0.2 2.1e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain DUF1793 PF08760.6 OAJ25159.1 - 0.00053 19.8 0.0 0.00077 19.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) NAD_binding_2 PF03446.10 OAJ25159.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 OAJ25159.1 - 0.089 12.8 0.0 0.12 12.4 0.0 1.4 1 1 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Cgr1 PF03879.9 OAJ25160.1 - 3.5e-16 59.3 22.6 3.7e-16 59.2 15.6 1.0 1 0 0 1 1 1 1 Cgr1 family Titin_Z PF09042.6 OAJ25160.1 - 0.06 12.9 1.0 0.06 12.9 0.7 2.4 1 1 1 2 2 2 0 Titin Z CytochromB561_N PF09786.4 OAJ25160.1 - 0.27 9.6 3.8 0.26 9.6 2.6 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Pilt PF15453.1 OAJ25160.1 - 1.3 8.6 8.8 1.4 8.5 6.1 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions PEARLI-4 PF05278.7 OAJ25160.1 - 1.6 8.0 11.6 1.9 7.7 8.0 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4337 PF14235.1 OAJ25160.1 - 2.7 7.8 9.7 3.7 7.3 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RNA_pol_3_Rpc31 PF11705.3 OAJ25160.1 - 2.9 7.7 8.0 3.1 7.6 5.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SPATIAL PF15256.1 OAJ25160.1 - 7.2 6.6 8.2 7.4 6.5 5.7 1.0 1 0 0 1 1 1 0 SPATIAL Atg14 PF10186.4 OAJ25162.1 - 1.2e-12 47.4 15.5 2.2e-07 30.1 0.0 4.1 2 2 1 3 3 3 2 UV radiation resistance protein and autophagy-related subunit 14 Tat PF00539.13 OAJ25162.1 - 0.18 11.4 1.4 0.36 10.4 0.9 1.4 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) APG6 PF04111.7 OAJ25162.1 - 0.29 10.1 0.9 27 3.6 0.8 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 PAP1 PF08601.5 OAJ25162.1 - 1.4 8.5 3.8 3.1 7.3 2.6 1.5 1 0 0 1 1 1 0 Transcription factor PAP1 E1_dh PF00676.15 OAJ25163.1 - 2.7e-83 279.1 0.0 3.2e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 OAJ25163.1 - 0.08 11.8 0.0 0.22 10.4 0.0 1.6 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase AAA PF00004.24 OAJ25164.1 - 4.9e-41 140.0 0.0 7.8e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ25164.1 - 6.4e-07 29.5 0.3 0.0026 17.9 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 OAJ25164.1 - 9.9e-06 25.5 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 OAJ25164.1 - 3e-05 23.0 0.0 6.7e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 OAJ25164.1 - 0.00019 21.4 0.1 0.0016 18.4 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 OAJ25164.1 - 0.00035 20.3 0.4 0.003 17.2 0.2 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 OAJ25164.1 - 0.00092 18.3 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 OAJ25164.1 - 0.0016 18.3 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ25164.1 - 0.0039 18.0 0.5 0.011 16.5 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_3 PF07726.6 OAJ25164.1 - 0.0041 16.7 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 OAJ25164.1 - 0.0043 16.4 0.6 0.74 9.1 0.1 2.4 1 1 1 2 2 2 1 AAA domain KaiC PF06745.8 OAJ25164.1 - 0.0061 15.7 0.1 0.18 10.8 0.0 2.3 1 1 1 2 2 2 1 KaiC AAA_33 PF13671.1 OAJ25164.1 - 0.0063 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ25164.1 - 0.007 16.0 0.3 0.015 15.0 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 OAJ25164.1 - 0.01 16.1 0.0 0.029 14.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 OAJ25164.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 OAJ25164.1 - 0.02 13.9 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 OAJ25164.1 - 0.03 13.2 0.0 0.063 12.1 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain TIP49 PF06068.8 OAJ25164.1 - 0.036 12.7 0.0 0.068 11.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_28 PF13521.1 OAJ25164.1 - 0.037 13.9 0.4 0.08 12.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 OAJ25164.1 - 0.064 12.9 0.2 0.43 10.2 0.0 2.1 1 1 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 OAJ25164.1 - 0.074 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 OAJ25164.1 - 0.077 11.9 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 OAJ25164.1 - 0.11 11.6 0.1 0.37 9.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 OAJ25164.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Histone PF00125.19 OAJ25164.1 - 0.14 12.3 0.2 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 AAA_24 PF13479.1 OAJ25164.1 - 0.14 11.7 0.1 0.35 10.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain NUDIX PF00293.23 OAJ25165.1 - 2.2e-16 59.7 0.1 6.6e-16 58.1 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain DUF1770 PF08589.5 OAJ25166.1 - 0.00018 22.0 1.5 0.00033 21.1 0.2 1.9 1 1 1 2 2 2 1 Fungal protein of unknown function (DUF1770) LELP1 PF15042.1 OAJ25167.1 - 0.042 14.0 3.9 0.053 13.7 2.7 1.1 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Vanabin-2 PF11437.3 OAJ25167.1 - 0.06 13.3 6.0 0.078 12.9 4.2 1.2 1 0 0 1 1 1 0 Vanadium-binding protein 2 zf-met PF12874.2 OAJ25167.1 - 0.48 10.6 0.1 0.48 10.6 0.1 2.7 2 1 1 3 3 3 0 Zinc-finger of C2H2 type Atrophin-1 PF03154.10 OAJ25168.1 - 0.00011 20.5 8.7 0.00012 20.4 6.0 1.1 1 0 0 1 1 1 1 Atrophin-1 family DUF3048 PF11258.3 OAJ25168.1 - 0.041 13.0 2.3 0.044 12.8 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) STAG PF08514.6 OAJ25168.1 - 0.21 11.2 2.3 0.34 10.6 1.6 1.4 1 1 0 1 1 1 0 STAG domain Conotoxin PF02950.12 OAJ25168.1 - 0.23 12.2 1.2 0.61 10.9 0.5 1.9 1 1 1 2 2 2 0 Conotoxin DUF2514 PF10721.4 OAJ25168.1 - 0.45 10.1 15.8 0.51 10.0 11.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) DUF2956 PF11169.3 OAJ25168.1 - 0.5 10.3 7.0 0.84 9.6 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF1682 PF07946.9 OAJ25168.1 - 1.3 7.8 8.5 1.6 7.5 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4337 PF14235.1 OAJ25168.1 - 3.6 7.4 6.5 5.2 6.8 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2058 PF09831.4 OAJ25168.1 - 5.5 6.8 9.9 7.6 6.3 6.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF2217 PF10265.4 OAJ25168.1 - 8.1 5.0 8.7 12 4.5 6.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Whi5 PF08528.6 OAJ25169.1 - 6.5e-10 38.3 0.0 1e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Whi5 like Fringe PF02434.11 OAJ25170.1 - 2e-08 33.8 0.0 3.4e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Fringe-like PGP_phosphatase PF09419.5 OAJ25171.1 - 1.3e-40 138.5 0.0 6.1e-36 123.3 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase FAD_binding_3 PF01494.14 OAJ25172.1 - 1e-16 60.9 3.9 7.8e-07 28.4 0.2 3.2 3 0 0 3 3 3 3 FAD binding domain Lycopene_cycl PF05834.7 OAJ25172.1 - 0.00014 20.9 0.1 0.31 9.9 0.0 2.6 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.19 OAJ25172.1 - 0.00019 20.4 0.0 0.016 14.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ25172.1 - 0.002 18.0 0.1 0.0081 16.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAJ25172.1 - 0.028 14.8 0.1 0.37 11.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 OAJ25172.1 - 0.048 12.4 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Rhodanese PF00581.15 OAJ25173.1 - 0.025 14.9 0.0 0.3 11.4 0.0 2.4 2 0 0 2 2 2 0 Rhodanese-like domain DDE_3 PF13358.1 OAJ25174.1 - 1.8e-29 102.3 0.0 2.7e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 OAJ25174.1 - 0.00014 21.9 0.0 0.00033 20.7 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix rve PF00665.21 OAJ25174.1 - 0.0003 20.8 0.0 0.00067 19.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain FTHFS PF01268.14 OAJ25176.1 - 1.1e-251 835.7 0.2 2e-251 834.8 0.0 1.5 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 OAJ25176.1 - 1.5e-63 212.6 0.9 1.5e-63 212.6 0.6 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 OAJ25176.1 - 3.1e-29 101.3 0.0 8.5e-29 99.9 0.0 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain F-box PF00646.28 OAJ25176.1 - 0.00041 19.9 0.4 0.00087 18.8 0.3 1.5 1 0 0 1 1 1 1 F-box domain Prefoldin PF02996.12 OAJ25176.1 - 0.3 10.7 0.3 0.8 9.3 0.0 1.8 2 0 0 2 2 2 0 Prefoldin subunit Mcp5_PH PF12814.2 OAJ25177.1 - 0.064 13.1 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology NDT80_PhoG PF05224.7 OAJ25178.1 - 2.5e-11 43.8 0.0 1.9e-10 41.0 0.0 2.4 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family 2-oxoacid_dh PF00198.18 OAJ25180.1 - 5e-79 264.8 0.0 7.4e-79 264.2 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 OAJ25180.1 - 2e-19 69.0 1.9 3.6e-19 68.1 1.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.1 OAJ25180.1 - 0.0011 19.2 0.1 0.73 10.2 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 OAJ25180.1 - 0.0026 17.4 0.0 0.24 11.1 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 OAJ25180.1 - 0.0046 16.1 16.4 0.065 12.3 6.2 2.4 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.14 OAJ25180.1 - 0.013 15.1 0.3 0.028 14.0 0.2 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF605 PF04652.11 OAJ25180.1 - 0.84 8.9 18.8 1.1 8.5 13.0 1.1 1 0 0 1 1 1 0 Vta1 like HSF_DNA-bind PF00447.12 OAJ25181.1 - 4.9e-35 119.8 0.1 8.9e-35 118.9 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 OAJ25181.1 - 3e-23 81.9 0.1 5.9e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Bromodomain PF00439.20 OAJ25182.1 - 2.6e-16 59.3 0.0 7e-16 57.9 0.0 1.6 2 0 0 2 2 2 1 Bromodomain CBM_6 PF03422.10 OAJ25182.1 - 0.0015 18.6 0.5 0.39 10.8 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) TFIIA PF03153.8 OAJ25182.1 - 0.0043 17.0 22.2 0.0043 17.0 15.4 3.1 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit SCAMP PF04144.8 OAJ25183.1 - 6.3e-44 149.9 2.3 7.5e-44 149.7 1.6 1.0 1 0 0 1 1 1 1 SCAMP family HAP1_N PF04849.8 OAJ25183.1 - 0.13 11.2 0.8 0.17 10.8 0.6 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region SAM_2 PF07647.12 OAJ25184.1 - 9e-10 38.2 0.0 1.7e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 OAJ25184.1 - 2.4e-06 27.6 0.0 5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.1 OAJ25184.1 - 0.14 12.1 0.2 0.34 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Ank_2 PF12796.2 OAJ25185.1 - 8.9e-17 61.2 0.1 3.1e-16 59.4 0.1 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ25185.1 - 1.4e-14 54.1 0.1 2e-07 31.3 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ25185.1 - 4.3e-13 49.0 0.4 1.4e-08 34.6 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ25185.1 - 2.8e-12 45.6 0.0 7.3e-05 22.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 OAJ25185.1 - 9.4e-12 44.1 2.4 3.8e-06 26.4 0.0 4.6 4 1 0 4 4 4 2 Ankyrin repeat SMC_N PF02463.14 OAJ25186.1 - 3.4e-68 229.1 28.7 3.4e-67 225.8 19.9 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 OAJ25186.1 - 3.6e-27 94.7 0.0 1.5e-26 92.7 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 OAJ25186.1 - 1.5e-13 51.5 3.7 1.5e-13 51.5 2.6 7.1 3 2 2 6 6 2 1 AAA domain AAA_21 PF13304.1 OAJ25186.1 - 6.1e-13 49.3 11.2 1.7e-06 28.2 0.2 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 OAJ25186.1 - 4e-05 23.0 0.0 8.4e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 OAJ25186.1 - 4.7e-05 20.9 29.9 4.7e-05 20.9 20.7 4.3 3 1 1 4 4 4 1 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 OAJ25186.1 - 8.8e-05 21.8 23.4 0.028 13.5 0.8 4.6 3 1 1 4 4 4 3 Reovirus sigma C capsid protein AAA_13 PF13166.1 OAJ25186.1 - 0.0019 16.7 14.9 0.0019 16.7 10.3 6.0 3 2 1 5 5 4 2 AAA domain TMF_DNA_bd PF12329.3 OAJ25186.1 - 0.0039 16.9 4.2 0.0039 16.9 2.9 11.1 9 2 3 12 12 11 2 TATA element modulatory factor 1 DNA binding SpoOE-like PF09388.5 OAJ25186.1 - 0.012 15.0 0.4 0.012 15.0 0.3 4.0 3 0 0 3 3 3 0 Spo0E like sporulation regulatory protein Img2 PF05046.9 OAJ25186.1 - 0.029 14.6 3.9 0.13 12.4 0.9 3.2 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Baculo_PEP_C PF04513.7 OAJ25186.1 - 0.098 12.4 15.4 0.17 11.7 0.4 4.9 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Thiolase_N PF00108.18 OAJ25187.1 - 5.7e-83 277.9 2.1 7.6e-83 277.5 1.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAJ25187.1 - 3.2e-49 165.4 0.5 8.7e-49 164.0 0.3 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 OAJ25187.1 - 3.6e-05 23.3 1.6 9.2e-05 22.0 1.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain RVT_2 PF07727.9 OAJ25190.1 - 1.3e-79 266.6 0.0 1.7e-79 266.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ25190.1 - 5.5e-15 55.5 0.2 4.5e-14 52.5 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain Autotransporter PF03797.14 OAJ25190.1 - 0.098 11.9 0.1 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Autotransporter beta-domain rve_3 PF13683.1 OAJ25190.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain GTP_cyclohydroI PF01227.17 OAJ25191.1 - 4.1e-75 250.9 0.1 6.5e-75 250.3 0.1 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 OAJ25191.1 - 0.001 18.9 0.0 0.0032 17.3 0.0 1.8 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 OAJ25191.1 - 0.015 15.0 0.1 0.044 13.5 0.1 1.8 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain NCD2 PF04905.8 OAJ25191.1 - 0.5 10.1 0.0 0.5 10.1 0.0 2.2 2 0 0 2 2 2 0 NAB conserved region 2 (NCD2) Abhydrolase_6 PF12697.2 OAJ25192.1 - 8.6e-25 87.9 0.3 8.6e-25 87.9 0.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ25192.1 - 1.8e-14 53.8 0.7 1.8e-09 37.4 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ25192.1 - 3.8e-08 33.2 0.1 6.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 OAJ25192.1 - 6.3e-05 21.5 0.0 8.2e-05 21.2 0.0 1.1 1 0 0 1 1 1 1 Ndr family Esterase PF00756.15 OAJ25192.1 - 6.5e-05 22.4 0.0 0.00013 21.5 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 OAJ25192.1 - 0.0034 17.2 0.0 0.0083 15.9 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 OAJ25192.1 - 0.0056 16.1 0.0 0.048 13.1 0.0 2.0 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Endosulfine PF04667.12 OAJ25193.1 - 1.7e-17 63.1 0.0 3.8e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Zn_clus PF00172.13 OAJ25194.1 - 3.9e-07 29.8 9.1 6.6e-07 29.1 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1777 PF08648.7 OAJ25194.1 - 0.00019 21.2 23.8 0.00019 21.2 16.5 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1777) Fungal_trans PF04082.13 OAJ25194.1 - 0.00037 19.4 0.2 0.03 13.2 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.11 OAJ25195.1 - 4.3e-27 94.7 25.5 4.3e-27 94.7 17.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 OAJ25196.1 - 3.5e-21 74.2 6.9 9.4e-11 41.1 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Pkinase PF00069.20 OAJ25196.1 - 2.7e-16 59.5 0.0 5.6e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ25196.1 - 1.3e-07 30.9 0.0 0.00093 18.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT PF02985.17 OAJ25196.1 - 5.7e-07 29.0 11.1 0.018 15.0 0.4 6.5 6 0 0 6 6 6 1 HEAT repeat Nucleoporin_N PF08801.6 OAJ25196.1 - 0.0019 16.9 2.4 0.21 10.3 0.5 3.3 2 2 2 4 4 4 2 Nup133 N terminal like Cohesin_HEAT PF12765.2 OAJ25196.1 - 0.28 11.1 2.5 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 OAJ25196.1 - 0.49 8.6 0.4 1.3 7.2 0.2 1.6 2 0 0 2 2 2 0 Adaptin N terminal region Myb_DNA-bind_4 PF13837.1 OAJ25199.1 - 0.0084 16.2 0.5 0.1 12.7 0.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain PfkB PF00294.19 OAJ25200.1 - 4.1e-17 62.2 0.0 2.9e-12 46.3 0.0 2.0 1 1 1 2 2 2 2 pfkB family carbohydrate kinase COX7C PF02935.11 OAJ25200.1 - 0.06 13.1 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc UBN2_2 PF14227.1 OAJ25202.1 - 1.2e-16 60.3 0.1 1.8e-16 59.8 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ25202.1 - 2.7e-11 43.2 0.2 4.3e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAJ25202.1 - 5.6e-07 29.0 0.0 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_3 PF14244.1 OAJ25202.1 - 7.1e-06 25.6 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 OAJ25202.1 - 0.00015 21.0 0.0 0.0003 20.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) RVP PF00077.15 OAJ25202.1 - 0.0047 16.8 0.0 0.009 15.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.18 OAJ25202.1 - 0.056 13.3 5.4 0.14 12.1 3.7 1.7 1 0 0 1 1 1 0 Zinc knuckle HA2 PF04408.18 OAJ25203.1 - 7.2e-20 70.9 0.0 6.2e-19 67.9 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ25203.1 - 8.9e-13 47.9 0.1 8.6e-12 44.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 OAJ25203.1 - 9.4e-12 44.7 0.0 2.6e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 OAJ25203.1 - 2.1e-06 27.3 0.0 5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ25203.1 - 0.00094 19.3 0.0 0.0033 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 OAJ25203.1 - 0.0037 17.6 5.9 0.23 11.7 0.0 2.7 3 0 0 3 3 3 2 AAA domain KaiC PF06745.8 OAJ25203.1 - 0.025 13.7 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 KaiC ERG4_ERG24 PF01222.12 OAJ25204.1 - 1.4e-139 465.3 4.1 1.6e-139 465.1 2.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 OAJ25204.1 - 3.1e-05 23.3 0.1 6.4e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 OAJ25204.1 - 0.00016 21.7 2.0 0.00034 20.6 0.0 2.7 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.9 OAJ25204.1 - 0.0054 16.9 0.0 0.018 15.2 0.0 1.9 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DDE_3 PF13358.1 OAJ25205.1 - 1.4e-28 99.4 0.0 4.1e-28 97.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAJ25205.1 - 1.7e-08 35.0 0.5 1.7e-08 35.0 0.3 3.0 2 1 1 3 3 3 1 Homeodomain-like domain rve PF00665.21 OAJ25205.1 - 0.0001 22.3 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_33 PF13592.1 OAJ25205.1 - 0.00032 20.1 0.1 0.00096 18.6 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_IS630 PF01710.11 OAJ25205.1 - 0.00065 19.3 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 OAJ25205.1 - 0.0009 19.3 1.8 0.0016 18.5 0.1 2.4 2 1 1 3 3 3 1 Winged helix-turn helix HTH_7 PF02796.10 OAJ25205.1 - 0.061 13.1 0.3 1.7 8.5 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DDE_Tnp_ISAZ013 PF07592.6 OAJ25205.1 - 0.15 10.8 0.1 3.3 6.3 0.0 2.1 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain SAPS PF04499.10 OAJ25206.1 - 0.031 12.9 3.4 0.048 12.3 2.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4448 PF14610.1 OAJ25207.1 - 0.015 14.8 0.2 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) BolA PF01722.13 OAJ25208.1 - 1.4e-15 57.0 0.0 2.1e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein GCD14 PF08704.5 OAJ25209.1 - 4.2e-72 242.5 5.3 6.7e-30 104.3 0.1 4.2 3 1 0 4 4 4 4 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 OAJ25209.1 - 0.0016 18.0 0.0 0.0038 16.7 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 OAJ25209.1 - 0.0028 17.6 0.1 0.0072 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 OAJ25209.1 - 0.045 12.7 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 OAJ25209.1 - 0.1 13.1 0.0 1.5 9.4 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ25209.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Nop14 PF04147.7 OAJ25209.1 - 3 5.6 17.8 4.9 4.9 12.4 1.2 1 0 0 1 1 1 0 Nop14-like family Sec39 PF08314.6 OAJ25210.1 - 0.12 10.3 0.1 0.18 9.7 0.1 1.2 1 0 0 1 1 1 0 Secretory pathway protein Sec39 Mito_carr PF00153.22 OAJ25211.1 - 9.1e-27 92.6 4.6 2.8e-15 55.8 0.0 2.4 3 0 0 3 3 3 2 Mitochondrial carrier protein Ribosomal_S24e PF01282.14 OAJ25212.1 - 2.5e-32 110.5 0.1 3.8e-32 109.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e NUDIX PF00293.23 OAJ25213.1 - 2.3e-13 49.9 0.0 3.9e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain EF_assoc_1 PF08355.7 OAJ25214.1 - 0.01 15.1 0.5 0.2 10.9 0.3 2.2 2 0 0 2 2 2 0 EF hand associated Tctex-1 PF03645.8 OAJ25218.1 - 3.1e-09 36.5 0.0 3.9e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Totivirus_coat PF05518.6 OAJ25218.1 - 3.3 5.4 11.6 4 5.1 8.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein Complex1_LYR PF05347.10 OAJ25219.1 - 1.3e-05 24.8 0.5 3e-05 23.7 0.3 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAJ25219.1 - 6e-05 23.1 0.5 0.00018 21.6 0.4 1.8 1 0 0 1 1 1 1 Complex1_LYR-like Kelch_4 PF13418.1 OAJ25220.1 - 4.5e-21 74.3 3.0 8.1e-07 28.7 0.0 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.1 OAJ25220.1 - 2.5e-15 56.1 13.0 0.0021 18.1 0.1 7.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 OAJ25220.1 - 1.6e-13 50.2 2.1 0.0024 17.9 0.0 6.1 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.1 OAJ25220.1 - 4.6e-13 48.7 4.1 0.00017 21.4 0.0 5.9 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 OAJ25220.1 - 9.6e-06 25.0 0.0 0.081 12.4 0.0 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 OAJ25220.1 - 0.0022 17.7 0.0 5.7 6.8 0.0 4.7 5 0 0 5 5 5 1 Kelch motif RCR PF12273.3 OAJ25221.1 - 9.2e-06 26.2 5.1 2e-05 25.1 3.5 1.5 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM51 PF15345.1 OAJ25221.1 - 0.0001 22.1 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 Shisa PF13908.1 OAJ25221.1 - 0.0014 18.8 0.2 0.0031 17.7 0.1 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator GRP PF07172.6 OAJ25221.1 - 0.002 18.5 1.9 0.0043 17.4 1.3 1.5 1 1 0 1 1 1 1 Glycine rich protein family Herpes_gE PF02480.11 OAJ25221.1 - 0.002 16.4 0.0 0.0022 16.3 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 OAJ25221.1 - 0.0067 16.7 0.1 0.014 15.7 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Sensor PF13796.1 OAJ25221.1 - 0.0068 16.0 4.0 0.061 12.9 0.0 2.1 2 0 0 2 2 2 1 Putative sensor DUF3357 PF11837.3 OAJ25221.1 - 0.015 15.1 1.0 0.032 14.0 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Rax2 PF12768.2 OAJ25221.1 - 0.017 14.3 0.1 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF3094 PF11293.3 OAJ25221.1 - 0.029 13.8 0.2 0.05 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) TMEM154 PF15102.1 OAJ25221.1 - 0.039 13.6 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family PgaD PF13994.1 OAJ25221.1 - 0.057 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 PgaD-like protein Mid2 PF04478.7 OAJ25221.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF912 PF06024.7 OAJ25221.1 - 2.2 8.3 4.2 0.79 9.8 0.2 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1049 PF06305.6 OAJ25221.1 - 3.1 7.3 7.5 1.4 8.4 3.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) IncA PF04156.9 OAJ25221.1 - 3.4 7.2 6.5 0.27 10.8 0.1 1.9 2 0 0 2 2 2 0 IncA protein DUF1180 PF06679.7 OAJ25221.1 - 8.4 6.2 12.3 1.3 8.8 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) CDP-OH_P_transf PF01066.16 OAJ25222.1 - 2.4e-11 43.8 6.7 2.4e-11 43.8 4.7 3.5 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.20 OAJ25223.1 - 2.7e-50 170.9 0.3 4.8e-50 170.1 0.0 1.5 2 0 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ25223.1 - 1.6e-43 148.6 0.0 2.3e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TFIIF_alpha PF05793.7 OAJ25223.1 - 9.2e-05 21.0 17.3 9.2e-05 21.0 12.0 2.1 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) C1_1 PF00130.17 OAJ25223.1 - 0.001 18.7 6.4 0.0021 17.7 4.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.18 OAJ25223.1 - 0.0025 17.6 0.4 0.005 16.6 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ25223.1 - 0.056 12.4 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-HC5HC2H_2 PF13832.1 OAJ25223.1 - 0.23 11.4 3.6 0.48 10.4 2.5 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain MIP-T3 PF10243.4 OAJ25223.1 - 0.41 9.0 32.4 0.028 12.9 18.2 1.9 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Pox_ser-thr_kin PF05445.6 OAJ25223.1 - 0.42 9.3 0.0 0.62 8.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FAM60A PF15396.1 OAJ25223.1 - 0.78 9.4 15.3 2.1 8.0 10.6 1.7 1 0 0 1 1 1 0 Protein Family FAM60A DUF2956 PF11169.3 OAJ25223.1 - 1.8 8.5 13.1 4.5 7.2 9.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Paf1 PF03985.8 OAJ25223.1 - 2.5 6.7 17.0 5.4 5.6 11.8 1.5 1 0 0 1 1 1 0 Paf1 DUF1510 PF07423.6 OAJ25223.1 - 3.5 6.9 18.5 9.9 5.4 12.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 OAJ25223.1 - 8.5 3.9 8.0 12 3.4 5.5 1.1 1 0 0 1 1 1 0 Ycf1 Cullin PF00888.17 OAJ25225.1 - 9.2e-148 493.3 0.0 2.7e-143 478.6 0.0 2.1 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 OAJ25225.1 - 4.4e-29 100.1 0.3 8.6e-29 99.1 0.2 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain Penicillinase_R PF03965.11 OAJ25225.1 - 0.02 14.9 0.0 0.091 12.8 0.0 2.2 1 0 0 1 1 1 0 Penicillinase repressor TrmB PF01978.14 OAJ25225.1 - 0.023 14.4 0.2 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Phyto-Amp PF15438.1 OAJ25226.1 - 0.002 17.7 1.8 0.24 11.0 0.2 2.1 1 1 1 2 2 2 2 Antigenic membrane protein of phytoplasma PTR PF12789.2 OAJ25226.1 - 0.04 13.7 0.1 0.064 13.1 0.1 1.3 1 0 0 1 1 1 0 Phage tail repeat like DUF1227 PF06777.6 OAJ25227.1 - 8.7e-57 190.9 0.1 1.7e-56 190.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 OAJ25227.1 - 9.2e-46 155.4 0.1 1.2e-40 138.7 0.0 2.4 2 0 0 2 2 2 2 DEAD_2 Helicase_C_2 PF13307.1 OAJ25227.1 - 1.3e-45 155.3 0.0 2.9e-45 154.2 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 OAJ25227.1 - 0.0033 16.2 0.2 0.051 12.3 0.1 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 OAJ25227.1 - 0.0075 16.1 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ25227.1 - 0.014 14.9 0.0 3 7.3 0.0 2.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ25227.1 - 0.039 14.1 0.1 4.1 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 OAJ25227.1 - 0.069 12.9 0.0 0.62 9.8 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain YtxC PF08812.6 OAJ25227.1 - 0.079 12.4 0.4 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 YtxC-like family AAA_11 PF13086.1 OAJ25227.1 - 0.12 11.9 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain HECT PF00632.20 OAJ25228.1 - 5e-92 308.4 0.0 7.4e-92 307.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 OAJ25228.1 - 1.9e-32 110.7 14.6 1.6e-10 40.6 1.9 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.25 OAJ25228.1 - 2.1e-14 53.0 0.1 4.8e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 C2 domain VanZ PF04892.7 OAJ25229.1 - 9.5e-09 35.3 1.3 1.9e-08 34.3 0.9 1.4 1 1 0 1 1 1 1 VanZ like family DUF1275 PF06912.6 OAJ25229.1 - 0.032 13.4 0.9 0.046 12.9 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) DBD_Tnp_Mut PF03108.10 OAJ25230.1 - 3.1e-08 33.0 0.2 9.6e-08 31.4 0.1 1.8 1 0 0 1 1 1 1 MuDR family transposase zf-BED PF02892.10 OAJ25230.1 - 5.6e-07 29.2 0.5 1.5e-06 27.8 0.3 1.7 1 0 0 1 1 1 1 BED zinc finger rve PF00665.21 OAJ25230.1 - 6.6e-07 29.4 0.0 1.5e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF4031 PF13223.1 OAJ25230.1 - 0.08 13.0 0.1 0.97 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4031) DUF4219 PF13961.1 OAJ25231.1 - 1.6e-05 24.1 0.1 2.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 OAJ25231.1 - 0.02 14.4 0.1 0.046 13.2 0.1 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Ribosomal_S3Ae PF01015.13 OAJ25232.1 - 9.3e-80 266.5 0.9 1.1e-79 266.3 0.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 OAJ25232.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region SET PF00856.23 OAJ25233.1 - 8e-05 22.9 0.0 0.02 15.1 0.0 2.4 2 0 0 2 2 2 2 SET domain SAF PF08666.7 OAJ25233.1 - 0.035 14.5 0.0 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 SAF domain FHA PF00498.21 OAJ25235.1 - 2.3e-05 24.4 0.0 4.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain NAM-associated PF14303.1 OAJ25236.1 - 0.32 11.3 10.8 0.4 11.0 7.5 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain YceG PF02618.11 OAJ25236.1 - 0.51 9.3 3.4 0.58 9.1 2.4 1.0 1 0 0 1 1 1 0 YceG-like family CRISPR_assoc PF08798.6 OAJ25236.1 - 0.8 9.4 10.2 1.3 8.7 7.1 1.5 1 1 0 1 1 1 0 CRISPR associated protein DUF3584 PF12128.3 OAJ25236.1 - 3.8 4.7 14.1 4.1 4.6 9.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DDE_Tnp_4 PF13359.1 OAJ25237.1 - 1.7e-06 27.7 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Solute_trans_a PF03619.11 OAJ25238.1 - 2e-86 289.7 8.6 2.7e-86 289.3 6.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha ABC_tran PF00005.22 OAJ25239.1 - 4.7e-45 153.2 0.1 2.6e-22 79.5 0.0 4.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 OAJ25239.1 - 4.2e-19 69.5 1.6 3.8e-07 30.3 0.0 4.3 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 OAJ25239.1 - 8.9e-15 54.5 1.7 0.011 14.9 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 OAJ25239.1 - 6.3e-10 38.4 0.2 0.00081 18.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 OAJ25239.1 - 1.9e-06 28.7 0.1 0.099 13.4 0.1 3.2 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 OAJ25239.1 - 2e-06 27.6 0.0 0.0047 16.8 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 OAJ25239.1 - 3.6e-06 26.6 0.1 0.011 15.1 0.0 3.1 3 0 0 3 3 2 2 AAA-like domain AAA_22 PF13401.1 OAJ25239.1 - 6.4e-06 26.3 0.0 0.32 11.1 0.0 4.2 5 0 0 5 5 4 2 AAA domain AAA_15 PF13175.1 OAJ25239.1 - 1.9e-05 23.8 0.4 0.42 9.5 0.0 4.3 4 1 0 5 5 4 1 AAA ATPase domain HEAT_2 PF13646.1 OAJ25239.1 - 2.3e-05 24.5 0.6 0.0071 16.6 0.0 4.2 4 1 1 5 5 4 1 HEAT repeats DUF258 PF03193.11 OAJ25239.1 - 3.1e-05 23.2 0.0 0.032 13.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 OAJ25239.1 - 3.2e-05 24.3 0.0 0.038 14.4 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 OAJ25239.1 - 3.3e-05 24.2 9.1 0.058 13.7 0.0 3.7 3 1 0 3 3 2 2 AAA domain NACHT PF05729.7 OAJ25239.1 - 3.5e-05 23.5 0.0 0.28 10.8 0.0 3.2 3 0 0 3 3 3 2 NACHT domain MMR_HSR1 PF01926.18 OAJ25239.1 - 6.5e-05 22.8 0.0 0.47 10.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 OAJ25239.1 - 8.5e-05 22.8 1.8 0.39 11.0 0.0 4.1 4 0 0 4 4 3 1 AAA domain HEAT_EZ PF13513.1 OAJ25239.1 - 0.00011 22.5 3.3 4.8 7.7 0.0 5.4 5 1 1 6 6 5 0 HEAT-like repeat Chromo PF00385.19 OAJ25239.1 - 0.00012 21.6 0.5 0.00028 20.4 0.0 1.9 2 0 0 2 2 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_33 PF13671.1 OAJ25239.1 - 0.00016 21.5 0.0 0.77 9.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_13 PF13166.1 OAJ25239.1 - 0.00029 19.4 0.1 1.1 7.5 0.0 3.4 3 1 0 3 3 3 1 AAA domain DUF87 PF01935.12 OAJ25239.1 - 0.00036 20.4 3.2 0.032 14.0 0.1 3.3 4 0 0 4 4 3 1 Domain of unknown function DUF87 AAA_25 PF13481.1 OAJ25239.1 - 0.0004 19.8 0.1 0.44 9.9 0.0 3.6 4 0 0 4 4 3 1 AAA domain MobB PF03205.9 OAJ25239.1 - 0.00043 19.9 0.3 0.61 9.7 0.0 3.2 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 OAJ25239.1 - 0.00063 19.8 0.0 0.88 9.7 0.0 2.8 2 0 0 2 2 2 1 RNA helicase FtsK_SpoIIIE PF01580.13 OAJ25239.1 - 0.00093 18.7 0.1 0.95 8.8 0.0 2.9 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 OAJ25239.1 - 0.0011 19.0 5.1 0.12 12.3 0.5 4.2 3 1 0 3 3 3 1 AAA ATPase domain CLASP_N PF12348.3 OAJ25239.1 - 0.0011 18.3 0.1 0.56 9.5 0.0 2.5 1 1 0 2 2 2 1 CLASP N terminal G-alpha PF00503.15 OAJ25239.1 - 0.0013 17.5 0.1 0.98 8.0 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit ArgK PF03308.11 OAJ25239.1 - 0.0015 17.3 0.3 0.48 9.1 0.0 2.9 2 0 0 2 2 2 1 ArgK protein HEAT PF02985.17 OAJ25239.1 - 0.0019 18.1 1.1 1.8 8.8 0.0 4.7 5 0 0 5 5 4 1 HEAT repeat Arch_ATPase PF01637.13 OAJ25239.1 - 0.0021 17.8 0.6 1.9 8.1 0.1 3.7 3 1 0 3 3 3 1 Archaeal ATPase AAA_28 PF13521.1 OAJ25239.1 - 0.0024 17.8 0.0 0.86 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 OAJ25239.1 - 0.0032 17.6 0.0 6.5 6.9 0.0 4.4 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 OAJ25239.1 - 0.0045 16.5 0.1 6.6 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 OAJ25239.1 - 0.0055 16.6 0.0 4.3 7.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 OAJ25239.1 - 0.0082 15.0 1.4 2.1 7.1 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain Zeta_toxin PF06414.7 OAJ25239.1 - 0.014 14.5 1.9 21 4.1 0.0 3.4 3 0 0 3 3 3 0 Zeta toxin cobW PF02492.14 OAJ25239.1 - 0.033 13.6 1.9 11 5.3 0.1 3.8 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 OAJ25239.1 - 0.058 12.9 0.5 4.1 6.8 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 OAJ25239.1 - 0.077 12.7 2.3 9.1 6.0 0.0 4.1 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 OAJ25240.1 - 2.5e-24 86.1 0.0 6.4e-23 81.5 0.0 2.5 2 1 0 2 2 2 1 ABC transporter SMC_N PF02463.14 OAJ25240.1 - 9.2e-08 31.5 0.2 0.0033 16.6 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAJ25240.1 - 2.8e-07 30.8 1.4 0.014 15.4 0.1 2.9 3 0 0 3 3 3 2 AAA domain Chromo PF00385.19 OAJ25240.1 - 4.8e-05 22.9 0.0 0.00012 21.6 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SbcCD_C PF13558.1 OAJ25240.1 - 0.00034 20.4 0.0 0.002 18.0 0.0 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 OAJ25240.1 - 0.00067 19.1 0.1 0.0013 18.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ25240.1 - 0.0012 18.8 0.7 0.03 14.2 0.5 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 OAJ25240.1 - 0.0015 18.0 0.1 0.005 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA-like domain Miro PF08477.8 OAJ25240.1 - 0.0058 17.1 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 OAJ25240.1 - 0.0066 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAJ25240.1 - 0.011 16.5 0.7 0.034 14.9 0.1 2.2 2 1 0 2 2 1 0 AAA domain DUF87 PF01935.12 OAJ25240.1 - 0.014 15.1 0.1 0.014 15.1 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_5 PF07728.9 OAJ25240.1 - 0.03 14.0 0.2 4.1 7.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 OAJ25240.1 - 0.032 14.1 0.1 0.32 10.8 0.1 2.5 2 2 0 2 2 2 0 AAA domain MobB PF03205.9 OAJ25240.1 - 0.04 13.6 0.3 0.27 10.9 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 OAJ25240.1 - 0.054 12.8 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 OAJ25240.1 - 0.055 13.7 0.0 0.055 13.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 OAJ25240.1 - 0.056 13.3 0.0 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 OAJ25240.1 - 0.063 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 OAJ25240.1 - 0.11 12.6 0.0 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 OAJ25240.1 - 0.11 12.6 0.0 0.37 10.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 OAJ25240.1 - 0.11 12.6 0.1 2.7 8.1 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) FERM_N PF09379.5 OAJ25240.1 - 0.11 12.5 0.1 0.41 10.7 0.1 2.0 1 1 0 1 1 1 0 FERM N-terminal domain AAA_18 PF13238.1 OAJ25240.1 - 0.13 12.6 2.8 0.14 12.4 0.1 2.5 2 2 0 2 2 2 0 AAA domain MAPEG PF01124.13 OAJ25241.1 - 4.4e-10 39.2 6.2 9.8e-10 38.1 4.3 1.8 1 1 0 1 1 1 1 MAPEG family Proteasome PF00227.21 OAJ25246.1 - 2.4e-58 196.5 0.1 3.2e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAJ25246.1 - 1.7e-15 55.9 1.3 5.7e-15 54.3 0.3 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature zf-CCCH PF00642.19 OAJ25247.1 - 7e-13 47.9 14.6 8.4e-07 28.5 1.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 OAJ25247.1 - 0.0009 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CART PF06373.6 OAJ25247.1 - 0.26 11.2 2.8 6.1 6.8 0.2 2.5 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) Spc24 PF08286.6 OAJ25248.1 - 5.6e-05 22.8 0.1 0.0046 16.6 0.0 2.3 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Muted PF14942.1 OAJ25248.1 - 0.0011 18.8 3.5 0.0018 18.1 2.4 1.2 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein ABC_membrane_2 PF06472.10 OAJ25248.1 - 0.018 14.1 0.4 0.029 13.4 0.3 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 LpxK PF02606.9 OAJ25248.1 - 0.12 11.2 0.9 0.2 10.5 0.6 1.3 1 1 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase DUF342 PF03961.8 OAJ25248.1 - 0.17 10.2 0.6 0.23 9.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Latarcin PF10279.4 OAJ25248.1 - 1.2 9.3 4.9 1.3 9.2 0.9 2.2 2 0 0 2 2 2 0 Latarcin precursor Med21 PF11221.3 OAJ25248.1 - 1.4 8.8 4.1 40 4.1 1.2 3.1 3 0 0 3 3 3 0 Subunit 21 of Mediator complex Mnd1 PF03962.10 OAJ25248.1 - 2.1 7.9 7.1 57 3.2 0.6 2.0 1 1 1 2 2 2 0 Mnd1 family CBFD_NFYB_HMF PF00808.18 OAJ25249.1 - 3.6e-16 58.9 0.1 7.2e-16 58.0 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 OAJ25249.1 - 0.004 16.8 0.0 0.0068 16.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 OAJ25249.1 - 0.074 13.1 0.0 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DEAD PF00270.24 OAJ25251.1 - 1.5e-24 86.3 0.0 2.9e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 OAJ25251.1 - 7.2e-13 48.9 1.0 4.3e-12 46.4 0.7 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 OAJ25251.1 - 5e-11 42.2 0.0 1.7e-10 40.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mito_carr PF00153.22 OAJ25251.1 - 2.1e-10 40.1 0.1 1.6e-06 27.7 0.0 2.7 2 0 0 2 2 2 2 Mitochondrial carrier protein CDT1 PF08839.6 OAJ25251.1 - 9.9e-06 25.5 0.0 2.3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.10 OAJ25251.1 - 0.0023 17.7 0.2 0.017 14.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Methyltransf_16 PF10294.4 OAJ25252.1 - 1.2e-15 57.4 0.0 6.4e-15 55.0 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Phage_min_tail PF05939.8 OAJ25252.1 - 0.041 13.8 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Phage minor tail protein JAB PF01398.16 OAJ25253.1 - 2.2e-07 30.5 0.0 1.7e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA-synt_1c PF00749.16 OAJ25256.1 - 1.5e-70 237.3 0.0 2.7e-70 236.5 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain ESSS PF10183.4 OAJ25257.1 - 4.8e-23 81.5 0.2 6.8e-23 81.0 0.2 1.3 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Gly-zipper_OmpA PF13436.1 OAJ25259.1 - 0.0012 18.4 0.9 0.0023 17.6 0.6 1.4 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain RVT_3 PF13456.1 OAJ25260.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase-like DNA_pol_viral_C PF00336.13 OAJ25260.1 - 0.015 14.5 0.2 0.037 13.2 0.0 1.6 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain Parvo_NS1 PF01057.12 OAJ25261.1 - 0.034 13.0 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF4203 PF13886.1 OAJ25262.1 - 8.6e-30 103.7 20.5 8.6e-30 103.7 14.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) RVT_1 PF00078.22 OAJ25262.1 - 5e-11 42.3 0.0 8.8e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pox_A14 PF05767.7 OAJ25262.1 - 0.58 10.1 1.6 1.8 8.5 1.1 1.8 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF2058 PF09831.4 OAJ25263.1 - 0.22 11.4 4.1 0.4 10.5 2.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) RNA_pol_Rpb2_6 PF00562.23 OAJ25264.1 - 1e-109 366.8 0.0 1.4e-109 366.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 OAJ25264.1 - 6.4e-31 106.8 0.0 9.2e-31 106.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 OAJ25264.1 - 6.6e-24 83.4 0.0 1.7e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 OAJ25264.1 - 6.1e-23 80.5 0.0 1.4e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 OAJ25264.1 - 1.2e-19 70.4 0.0 2.8e-19 69.3 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 OAJ25264.1 - 5.5e-17 61.7 0.1 1.2e-14 54.3 0.0 3.2 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 7 ThuA PF06283.6 OAJ25267.1 - 1.5e-57 194.8 3.8 1.3e-46 159.0 0.0 2.8 3 0 0 3 3 3 2 Trehalose utilisation Zip PF02535.17 OAJ25267.1 - 4.2 6.2 6.6 6 5.7 4.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Pkinase PF00069.20 OAJ25268.1 - 8.4e-72 241.4 0.0 1e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ25268.1 - 7.8e-29 100.5 0.1 1.2e-28 99.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ25268.1 - 1.2e-05 24.4 0.1 4.9e-05 22.4 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 OAJ25268.1 - 0.00026 20.1 0.1 0.00059 18.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ25268.1 - 0.015 15.0 0.6 0.17 11.5 0.3 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 OAJ25268.1 - 0.058 12.7 0.1 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family RNA_pol_L_2 PF13656.1 OAJ25269.1 - 3.6e-28 96.8 0.0 4.8e-28 96.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 OAJ25269.1 - 4.1e-09 35.4 0.0 5.8e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain zf-C2H2 PF00096.21 OAJ25269.1 - 0.065 13.5 0.5 0.12 12.7 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Kinesin-related PF06548.6 OAJ25269.1 - 0.095 11.2 2.8 0.12 10.8 1.9 1.1 1 0 0 1 1 1 0 Kinesin-related ox_reductase_C PF08635.5 OAJ25270.1 - 2e-77 257.4 0.1 3.1e-77 256.8 0.1 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 OAJ25270.1 - 3.2e-20 72.8 0.0 9.4e-20 71.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold ZZ PF00569.12 OAJ25277.1 - 2.9e-09 36.3 64.7 2.1e-05 23.9 1.8 6.6 6 1 0 6 6 6 4 Zinc finger, ZZ type PB1 PF00564.19 OAJ25277.1 - 1.1e-05 24.9 0.1 2.3e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 PB1 domain Trp_DMAT PF11991.3 OAJ25278.1 - 2.3e-57 194.8 0.1 3.2e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase WD40 PF00400.27 OAJ25279.1 - 1.3e-59 196.0 24.6 2.5e-09 36.6 0.0 9.4 8 1 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 OAJ25279.1 - 7.9e-12 44.7 0.1 1.5e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ25279.1 - 8.4e-10 38.0 0.1 1.7e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 OAJ25279.1 - 2.6e-09 35.7 13.7 0.058 11.5 0.3 6.5 3 2 3 6 6 6 6 Nucleoporin Nup120/160 RNA_lig_T4_1 PF09511.5 OAJ25280.1 - 5.2e-79 264.7 0.0 9.1e-79 263.9 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 OAJ25280.1 - 1.4e-23 83.6 0.2 1.8e-14 53.9 0.0 2.4 1 1 1 2 2 2 2 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 OAJ25280.1 - 2.2e-17 63.1 0.0 8.5e-17 61.2 0.0 1.9 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain KTI12 PF08433.5 OAJ25280.1 - 0.02 14.0 0.2 1.1 8.4 0.2 2.3 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 OAJ25280.1 - 0.056 13.3 0.0 0.2 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain MTHFR PF02219.12 OAJ25281.1 - 1e-110 369.3 0.0 1.4e-110 368.9 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF3479 PF11965.3 OAJ25281.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) ThiF PF00899.16 OAJ25282.1 - 1.5e-15 57.2 0.0 2.5e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 ThiF family Pkinase PF00069.20 OAJ25284.1 - 2e-67 227.1 0.0 4.2e-67 226.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ25284.1 - 3.4e-48 163.9 0.0 5.8e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ25284.1 - 5.7e-05 22.2 0.0 0.00017 20.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAJ25284.1 - 0.045 13.4 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family RTTN_N PF14726.1 OAJ25284.1 - 0.15 12.6 1.8 1.7 9.2 0.1 2.7 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning 2-oxoacid_dh PF00198.18 OAJ25285.1 - 1.4e-79 266.6 0.1 1.9e-79 266.2 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 OAJ25285.1 - 1.2e-20 72.8 5.0 1.3e-20 72.7 2.1 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 OAJ25285.1 - 2.6e-17 62.1 0.1 5.7e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 OAJ25285.1 - 5.9e-05 22.6 1.9 0.24 11.1 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like DNA_alkylation PF08713.6 OAJ25285.1 - 0.057 12.9 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 DNA alkylation repair enzyme RR_TM4-6 PF06459.7 OAJ25285.1 - 1.5 8.6 5.0 2.9 7.7 3.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.9 OAJ25285.1 - 3.7 7.1 5.5 1 9.0 1.5 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) ELL PF10390.4 OAJ25285.1 - 4.9 6.2 9.4 16 4.6 6.5 1.8 1 1 0 1 1 1 0 RNA polymerase II elongation factor ELL DUF2937 PF11157.3 OAJ25286.1 - 0.82 8.9 10.3 5.5 6.2 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Nuf2 PF03800.9 OAJ25287.1 - 3.1e-31 108.3 1.6 3.8e-31 108.0 0.0 1.9 2 1 0 2 2 2 1 Nuf2 family Reo_sigmaC PF04582.7 OAJ25287.1 - 0.3 10.2 3.3 0.98 8.5 0.8 2.2 1 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF4473 PF14747.1 OAJ25287.1 - 0.67 10.2 8.1 5.2 7.3 0.4 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4473) Atg14 PF10186.4 OAJ25287.1 - 2 7.3 35.2 0.4 9.5 11.1 2.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 GAS PF13851.1 OAJ25287.1 - 4.6 6.3 36.6 4.5 6.4 15.9 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2935 PF11155.3 OAJ25287.1 - 6.5 6.8 12.8 1.1 9.3 0.4 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) SIR2 PF02146.12 OAJ25288.1 - 2.3e-51 174.0 0.0 1.5e-50 171.4 0.0 2.2 2 1 0 2 2 2 1 Sir2 family DUF592 PF04574.8 OAJ25288.1 - 1.8e-08 34.0 0.3 2.4e-07 30.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF592) WD40 PF00400.27 OAJ25289.1 - 1.8e-16 59.3 9.0 1.8e-06 27.6 0.1 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat DLIC PF05783.6 OAJ25289.1 - 0.91 8.1 3.7 2.1 6.9 2.5 1.6 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Arf PF00025.16 OAJ25290.1 - 1.6e-64 216.3 0.0 1.7e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 OAJ25290.1 - 6.8e-09 35.1 0.0 8.9e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 OAJ25290.1 - 2.2e-08 33.2 0.1 4.2e-05 22.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 OAJ25290.1 - 4.5e-08 32.6 0.0 5.6e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ25290.1 - 1.1e-07 32.3 0.0 1.6e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 OAJ25290.1 - 2.2e-06 27.5 0.0 3.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 OAJ25290.1 - 1.9e-05 23.9 0.0 2.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 OAJ25290.1 - 0.0055 16.1 0.0 0.17 11.2 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 OAJ25290.1 - 0.019 14.4 0.0 0.046 13.2 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CENP-M PF11111.3 OAJ25290.1 - 0.049 12.8 0.0 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 Centromere protein M (CENP-M) cobW PF02492.14 OAJ25290.1 - 0.079 12.3 0.0 4.7 6.6 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KOW PF00467.24 OAJ25291.1 - 7.7e-09 34.9 1.6 1.7e-08 33.8 1.1 1.6 1 0 0 1 1 1 1 KOW motif dsDNA_bind PF01984.15 OAJ25292.1 - 3.1e-26 91.4 11.7 2e-25 88.8 8.1 1.9 1 1 0 1 1 1 1 Double-stranded DNA-binding domain TilS PF09179.6 OAJ25292.1 - 0.89 9.6 3.2 0.96 9.5 0.8 2.0 2 0 0 2 2 2 0 TilS substrate binding domain PIG-S PF10510.4 OAJ25293.1 - 3.8e-107 359.1 0.0 5.6e-107 358.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Myosin_head PF00063.16 OAJ25294.1 - 2.7e-243 809.0 0.6 2.7e-243 809.0 0.4 1.9 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 OAJ25294.1 - 1e-34 118.5 1.8 1e-34 118.5 1.2 2.4 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 OAJ25294.1 - 5.9e-07 28.5 32.5 0.18 11.5 0.2 7.0 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 OAJ25294.1 - 0.0016 18.5 0.2 0.0094 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain TPR_MLP1_2 PF07926.7 OAJ25294.1 - 0.0022 17.7 6.0 0.0022 17.7 4.1 2.7 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein DivIC PF04977.10 OAJ25294.1 - 0.0028 17.0 6.2 0.0028 17.0 4.3 3.1 2 1 0 2 2 2 1 Septum formation initiator AAA_19 PF13245.1 OAJ25294.1 - 0.046 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 OAJ25294.1 - 0.24 10.5 5.0 1.2 8.2 0.2 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Dynactin PF12455.3 OAJ25296.1 - 2.1e-50 171.1 1.0 2.1e-50 171.1 0.7 3.8 4 0 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 OAJ25296.1 - 4.5e-19 67.9 1.1 8.7e-19 67.0 0.8 1.5 1 0 0 1 1 1 1 CAP-Gly domain GAS PF13851.1 OAJ25296.1 - 0.021 14.0 77.2 0.056 12.6 12.6 4.7 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding RNA_pol_Rpb1_5 PF04998.12 OAJ25299.1 - 2.7e-89 299.0 0.0 6.5e-89 297.8 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 OAJ25299.1 - 8.7e-60 201.4 0.0 1.6e-59 200.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 OAJ25299.1 - 3.3e-34 117.9 0.0 6.9e-34 116.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 OAJ25299.1 - 1.1e-28 100.4 1.7 2.3e-23 83.0 0.0 4.1 5 0 0 5 5 5 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 OAJ25299.1 - 7.5e-22 77.1 0.0 2.6e-21 75.3 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 CDC45 PF02724.9 OAJ25299.1 - 2.2 6.2 26.9 0.72 7.8 12.1 2.3 2 0 0 2 2 2 0 CDC45-like protein adh_short PF00106.20 OAJ25300.1 - 2.2e-29 102.4 0.0 2.8e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ25300.1 - 4.3e-21 75.7 0.0 5.2e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ25300.1 - 5.1e-13 49.0 0.0 7.5e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAJ25300.1 - 0.024 14.3 0.2 0.055 13.2 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Requiem_N PF14051.1 OAJ25301.1 - 0.048 13.5 0.1 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. DUF2235 PF09994.4 OAJ25302.1 - 1.7e-65 221.1 0.0 2.5e-65 220.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 OAJ25302.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2235 PF09994.4 OAJ25303.1 - 2.5e-66 223.9 0.0 3.7e-66 223.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 OAJ25303.1 - 0.028 14.1 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Gln-synt_C PF00120.19 OAJ25304.1 - 4e-59 199.8 0.0 4.8e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 OAJ25304.1 - 5.8e-19 67.4 0.0 1.1e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain PAPS_reduct PF01507.14 OAJ25305.1 - 3e-20 72.7 0.0 5.3e-15 55.6 0.0 2.6 2 1 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family DUF2235 PF09994.4 OAJ25306.1 - 2.4e-65 220.6 0.0 3.3e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.4 OAJ25307.1 - 5e-56 190.1 0.0 4.8e-55 186.8 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 OAJ25307.1 - 0.003 17.3 0.1 0.0059 16.3 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hormone_recep PF00104.25 OAJ25307.1 - 0.032 13.3 0.0 0.64 9.1 0.0 2.2 2 0 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor Hepar_II_III PF07940.8 OAJ25308.1 - 3.3e-10 39.9 1.7 1.4e-09 37.9 0.2 2.3 2 0 0 2 2 2 1 Heparinase II/III-like protein SH3_9 PF14604.1 OAJ25309.1 - 3.8e-16 58.4 0.2 4.8e-16 58.0 0.1 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ25309.1 - 3.5e-13 48.7 0.1 4.5e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ25309.1 - 7.1e-08 31.8 0.0 1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain LRR_4 PF12799.2 OAJ25310.1 - 6.7e-12 44.7 2.2 9.6e-11 41.0 0.2 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ25310.1 - 5e-11 42.1 1.8 1e-10 41.1 1.2 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 OAJ25310.1 - 3.4e-08 32.4 3.8 0.1 12.6 0.1 4.1 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 OAJ25310.1 - 6.1e-05 22.5 3.5 1.8 9.1 0.1 4.1 3 0 0 3 3 3 2 Leucine rich repeat DUF1772 PF08592.6 OAJ25311.1 - 5.7e-13 48.7 1.3 9.5e-13 48.0 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Cation_efflux PF01545.16 OAJ25312.1 - 3.7e-37 127.9 8.2 4.9e-37 127.5 5.7 1.2 1 0 0 1 1 1 1 Cation efflux family Pkinase PF00069.20 OAJ25314.1 - 4.5e-30 104.6 0.0 3.7e-19 68.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ25314.1 - 3.2e-13 49.3 0.0 1.3e-08 34.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ25314.1 - 0.002 17.1 0.0 0.73 8.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Urm1 PF09138.6 OAJ25315.1 - 4.5e-32 110.0 0.0 7e-32 109.4 0.0 1.3 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) His_Phos_1 PF00300.17 OAJ25315.1 - 7.2e-25 87.9 0.2 3.6e-24 85.6 0.1 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ThiS PF02597.15 OAJ25315.1 - 0.018 15.4 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 ThiS family DAGAT PF03982.8 OAJ25316.1 - 2.3e-94 315.4 0.0 1.3e-49 168.5 0.0 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase Glyco_trans_2_3 PF13632.1 OAJ25316.1 - 0.021 14.5 1.7 1.8 8.2 0.1 2.9 3 0 0 3 3 3 0 Glycosyl transferase family group 2 DUF2235 PF09994.4 OAJ25317.1 - 5.9e-57 193.1 0.0 9.8e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Tim17 PF02466.14 OAJ25318.1 - 1.8e-20 73.2 9.4 2.8e-20 72.6 6.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PRCC PF10253.4 OAJ25318.1 - 3.7 8.2 11.9 4.9 7.8 8.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF2235 PF09994.4 OAJ25319.1 - 4.7e-59 200.0 0.0 6.6e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 OAJ25319.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Mgm101p PF06420.7 OAJ25320.1 - 1.9e-85 284.4 0.0 2.3e-85 284.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 RRM_1 PF00076.17 OAJ25321.1 - 5.3e-13 48.4 0.0 8.1e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ25321.1 - 3e-12 46.3 0.0 4.6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ25321.1 - 0.017 14.9 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAF4 PF05236.9 OAJ25321.1 - 4.4 6.5 9.5 14 4.8 5.9 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family RasGAP_C PF03836.10 OAJ25325.1 - 7.4e-44 148.8 5.9 7.4e-44 148.8 4.1 2.3 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 OAJ25325.1 - 3e-40 137.9 4.6 3.7e-40 137.7 0.0 3.0 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 OAJ25325.1 - 1.3e-22 77.2 28.4 0.02 14.4 0.0 10.0 9 0 0 9 9 9 8 IQ calmodulin-binding motif CH PF00307.26 OAJ25325.1 - 3.6e-12 46.2 0.0 8.8e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain PAZ_siRNAbind PF12212.3 OAJ25325.1 - 0.11 12.1 0.3 17 5.0 0.0 2.6 2 0 0 2 2 2 0 Piwi/Argonaute/Zwille siRNA-binding domain Arch_ATPase PF01637.13 OAJ25326.1 - 8.4e-11 42.0 0.0 2.3e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase AAA_29 PF13555.1 OAJ25326.1 - 0.36 10.3 1.4 0.98 8.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ25326.1 - 0.69 9.8 5.4 3.4 7.5 0.3 3.6 2 2 1 3 3 3 0 AAA ATPase domain UDG PF03167.14 OAJ25327.1 - 7.2e-21 74.2 0.0 1.5e-11 43.9 0.0 2.3 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily SOG2 PF10428.4 OAJ25327.1 - 6.8 5.2 9.9 11 4.5 6.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein adh_short PF00106.20 OAJ25328.1 - 8.5e-11 42.0 0.0 1.3e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ25328.1 - 0.04 13.5 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.1 OAJ25328.1 - 0.052 13.3 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 OAJ25328.1 - 0.069 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_deac_1 PF01522.16 OAJ25329.1 - 7.3e-14 51.4 0.0 1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide deacetylase UBN2 PF14223.1 OAJ25330.1 - 1.4e-15 57.1 0.3 2.3e-15 56.4 0.2 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAJ25330.1 - 4.1e-15 55.3 0.1 6.8e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Zn_clus PF00172.13 OAJ25333.1 - 1.9e-06 27.6 6.8 3.4e-06 26.8 4.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.4 OAJ25333.1 - 0.11 12.2 1.3 0.21 11.3 0.9 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Xan_ur_permease PF00860.15 OAJ25334.1 - 5.6e-27 94.2 27.7 1.8e-25 89.2 19.2 2.2 1 1 0 1 1 1 1 Permease family Sulfate_transp PF00916.15 OAJ25334.1 - 0.00077 18.5 5.2 0.0013 17.8 3.0 1.8 1 1 0 1 1 1 1 Sulfate transporter family F-box-like PF12937.2 OAJ25336.1 - 0.19 11.5 2.6 0.41 10.3 0.2 2.6 3 0 0 3 3 3 0 F-box-like Ribosomal_L18p PF00861.17 OAJ25338.1 - 3.1e-39 133.8 1.5 4.6e-39 133.2 0.0 2.0 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 OAJ25338.1 - 1.8e-34 118.1 5.2 4.5e-34 116.8 3.6 1.7 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region MtrA PF04208.9 OAJ25338.1 - 0.053 12.9 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A UPF0449 PF15136.1 OAJ25338.1 - 0.11 12.7 1.0 0.21 11.7 0.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 PI-PLC-X PF00388.14 OAJ25340.1 - 4.7e-49 165.5 0.0 8.1e-49 164.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 OAJ25340.1 - 2.4e-37 127.5 0.0 4.9e-37 126.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 OAJ25340.1 - 7.6e-08 32.2 0.2 1.8e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.12 OAJ25340.1 - 0.072 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family FA_desaturase PF00487.19 OAJ25342.1 - 0.19 11.1 0.9 0.36 10.2 0.6 1.4 1 0 0 1 1 1 0 Fatty acid desaturase DUF2077 PF09850.4 OAJ25342.1 - 0.25 10.7 3.6 0.21 10.9 1.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) Ribosomal_L15e PF00827.12 OAJ25345.1 - 6.4e-88 293.2 8.4 7.6e-88 293.0 5.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 DUF4149 PF13664.1 OAJ25346.1 - 0.056 13.5 0.1 0.062 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) PK PF00224.16 OAJ25347.1 - 4.6e-159 528.6 1.0 5.6e-159 528.3 0.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 OAJ25347.1 - 4.4e-32 110.0 0.0 1.2e-31 108.7 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 OAJ25347.1 - 3.8e-05 22.6 1.1 0.00017 20.5 0.8 2.1 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 OAJ25347.1 - 0.00012 21.1 0.1 0.0022 16.9 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Cellulase PF00150.13 OAJ25347.1 - 0.069 12.3 0.0 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Peptidase_U32 PF01136.14 OAJ25347.1 - 0.081 11.8 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family U32 RRM_6 PF14259.1 OAJ25354.1 - 5.2e-11 42.3 0.0 6.9e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ25354.1 - 8.4e-09 35.1 0.0 1.2e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ25354.1 - 2.8e-08 33.2 0.0 3.6e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NapD PF03927.8 OAJ25354.1 - 0.041 13.7 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 NapD protein RRM_3 PF08777.6 OAJ25354.1 - 0.041 13.7 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif DUF605 PF04652.11 OAJ25355.1 - 4.4 6.6 28.7 6 6.1 19.9 1.1 1 0 0 1 1 1 0 Vta1 like Chs3p PF12271.3 OAJ25356.1 - 2.1e-117 391.3 17.7 2.4e-117 391.0 12.3 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Methyltransf_16 PF10294.4 OAJ25357.1 - 2.2e-41 141.1 0.0 3.1e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 OAJ25357.1 - 0.00043 20.8 0.0 0.00069 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ25357.1 - 0.0011 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 OAJ25357.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Dioxygenase_C PF00775.16 OAJ25358.1 - 3e-06 26.6 0.1 6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Dioxygenase HIT PF01230.18 OAJ25359.1 - 2.4e-16 60.0 0.0 4.5e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 OAJ25359.1 - 2.3e-07 31.0 0.0 7.4e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 OAJ25359.1 - 0.013 15.1 0.0 0.037 13.6 0.0 1.8 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 PHD PF00628.24 OAJ25361.1 - 0.0001 21.8 10.8 0.00022 20.8 7.5 1.5 1 0 0 1 1 1 1 PHD-finger Aldo_ket_red PF00248.16 OAJ25362.1 - 6.8e-70 235.0 0.0 7.7e-70 234.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UVR PF02151.14 OAJ25362.1 - 0.097 12.2 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif rve PF00665.21 OAJ25364.1 - 1.8e-05 24.8 0.0 3.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.1 OAJ25364.1 - 0.028 14.0 0.1 0.092 12.4 0.1 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.1 OAJ25364.1 - 0.035 13.6 0.1 0.07 12.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF659 PF04937.10 OAJ25367.1 - 5.3e-05 22.7 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.9 OAJ25367.1 - 0.00029 20.4 0.0 0.00074 19.0 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PTPA PF03095.10 OAJ25369.1 - 5.5e-87 291.7 0.0 7.2e-87 291.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein SecY PF00344.15 OAJ25370.1 - 1.6e-98 329.8 8.1 1.9e-98 329.5 5.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 OAJ25370.1 - 3e-17 61.8 0.3 1.1e-16 60.0 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p Claudin_3 PF06653.6 OAJ25370.1 - 0.8 9.4 5.2 1.2 8.7 0.0 3.3 3 1 0 3 3 3 0 Tight junction protein, Claudin-like Histone PF00125.19 OAJ25371.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Lact_bio_phlase PF09508.5 OAJ25372.1 - 0.027 12.1 0.0 0.037 11.6 0.0 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase AhpC-TSA PF00578.16 OAJ25374.1 - 8.7e-22 77.1 0.0 1.4e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 OAJ25374.1 - 5.6e-14 51.9 0.0 8.4e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin MSA-2c PF12238.3 OAJ25374.1 - 1.5 8.4 10.5 2.3 7.8 7.3 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c MSP1_C PF07462.6 OAJ25374.1 - 5.8 5.1 8.1 7.6 4.7 5.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Abhydrolase_6 PF12697.2 OAJ25376.1 - 7.9e-31 107.7 1.3 2e-30 106.3 0.9 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ25376.1 - 5.3e-15 55.5 0.1 9.7e-15 54.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ25376.1 - 1.3e-10 41.1 0.2 1.1e-09 38.2 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family CMD PF02627.15 OAJ25376.1 - 1.3e-06 28.1 2.0 9.1e-06 25.4 0.0 2.9 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family Hydrolase_4 PF12146.3 OAJ25376.1 - 0.0086 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 OAJ25376.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 OAJ25376.1 - 0.083 12.3 0.0 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Zn_clus PF00172.13 OAJ25377.1 - 1.3e-07 31.3 9.6 2.4e-07 30.5 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box PF00646.28 OAJ25378.1 - 1.7e-09 37.0 0.7 4.2e-09 35.8 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ25378.1 - 0.00087 18.9 0.2 0.0021 17.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 OAJ25378.1 - 0.0073 16.0 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 F-box-like domain DUF1771 PF08590.5 OAJ25379.1 - 5.3e-18 64.7 3.7 7.8e-18 64.2 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 OAJ25379.1 - 2.5e-15 56.4 0.0 4.7e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Smr domain DUF3450 PF11932.3 OAJ25380.1 - 0.0024 17.1 0.1 0.071 12.3 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) NPV_P10 PF05531.7 OAJ25380.1 - 0.0091 16.2 0.2 1.4 9.1 0.0 2.2 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein COMP PF11598.3 OAJ25380.1 - 0.072 13.1 1.0 0.23 11.5 0.1 2.1 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein LEAP-2 PF07359.6 OAJ25380.1 - 0.078 12.6 0.2 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Hamartin PF04388.7 OAJ25385.1 - 4.7e-17 61.9 0.0 4.7e-17 61.9 0.0 4.2 4 1 1 5 5 5 2 Hamartin protein Phlebovirus_NSM PF07246.6 OAJ25385.1 - 1.8 7.6 6.7 0.95 8.5 2.5 2.0 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M tRNA-synt_1c PF00749.16 OAJ25386.1 - 3.1e-102 341.4 0.0 6e-102 340.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 OAJ25386.1 - 1.5e-29 102.6 0.0 2.5e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 OAJ25386.1 - 2.5e-29 102.1 0.0 8.9e-29 100.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 OAJ25386.1 - 3.2e-08 34.1 10.0 3.2e-08 34.1 6.9 3.2 3 1 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Ribosomal_S5 PF00333.15 OAJ25387.1 - 1.9e-28 98.0 2.2 2.1e-28 97.8 0.8 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 OAJ25387.1 - 1.2e-21 75.7 0.1 2.1e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain RNA_pol PF00940.14 OAJ25387.1 - 0.17 10.3 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 DNA-dependent RNA polymerase FoP_duplication PF13865.1 OAJ25387.1 - 7.9 7.0 7.2 18 5.8 5.0 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 zf-Apc11 PF12861.2 OAJ25388.1 - 4.9e-31 106.4 9.1 6.3e-31 106.0 6.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 OAJ25388.1 - 3.3e-26 91.2 8.8 4.4e-26 90.7 6.1 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 OAJ25388.1 - 1.7e-06 27.7 14.9 5.7e-06 26.0 10.3 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 OAJ25388.1 - 1.7e-05 24.3 11.5 6.5e-05 22.5 8.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ25388.1 - 0.0032 17.4 12.0 0.064 13.2 8.3 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ25388.1 - 0.075 12.7 12.9 0.68 9.6 8.9 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 OAJ25388.1 - 0.55 10.2 9.8 1.4 8.9 6.8 1.8 1 1 0 1 1 1 0 RING-like domain zf-HC5HC2H_2 PF13832.1 OAJ25388.1 - 0.68 9.9 8.9 0.39 10.7 4.9 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-Nse PF11789.3 OAJ25388.1 - 1.4 8.5 6.5 2.4 7.7 4.5 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 OAJ25388.1 - 3.7 7.6 10.6 17 5.5 7.4 2.1 1 1 0 1 1 1 0 RING-variant domain TAFII28 PF04719.9 OAJ25389.1 - 9.6e-24 83.0 0.0 1.3e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF572 PF04502.8 OAJ25389.1 - 0.2 10.8 2.8 0.28 10.3 1.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) M_domain PF12938.2 OAJ25389.1 - 3.9 7.2 11.7 6.6 6.4 8.1 1.3 1 0 0 1 1 1 0 M domain of GW182 Peptidase_M14 PF00246.19 OAJ25390.1 - 9.2e-06 25.4 0.0 0.00024 20.8 0.0 2.4 1 1 0 1 1 1 1 Zinc carboxypeptidase UPF0184 PF03670.8 OAJ25390.1 - 0.12 12.5 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Sel1 PF08238.7 OAJ25391.1 - 1.2e-16 60.7 26.3 0.0019 18.7 0.1 8.8 9 0 0 9 9 9 5 Sel1 repeat TPR_11 PF13414.1 OAJ25391.1 - 0.0018 17.9 2.5 2.8 7.6 0.0 4.2 5 0 0 5 5 5 2 TPR repeat TPR_1 PF00515.23 OAJ25391.1 - 0.0081 15.7 3.7 0.24 11.0 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ25391.1 - 0.017 15.0 1.0 0.58 10.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ25391.1 - 0.046 13.5 0.6 0.94 9.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ25391.1 - 0.084 12.8 0.0 0.084 12.8 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ25391.1 - 0.47 10.3 0.0 0.47 10.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ25391.1 - 3.8 8.1 6.7 86 3.9 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Ribosomal_L27e PF01777.13 OAJ25392.1 - 4.4e-38 129.2 1.3 6.8e-38 128.6 0.9 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 OAJ25392.1 - 0.00017 21.1 0.6 0.00039 20.0 0.4 1.6 1 0 0 1 1 1 1 KOW motif Ribosom_S12_S23 PF00164.20 OAJ25393.1 - 2e-38 130.5 1.0 2.3e-38 130.3 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Arrestin_C PF02752.17 OAJ25394.1 - 1.1e-14 54.6 0.0 6.7e-14 52.1 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 OAJ25394.1 - 6e-08 32.6 0.0 3.3e-05 23.7 0.0 2.6 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Serglycin PF04360.7 OAJ25394.1 - 0.45 10.2 0.0 0.45 10.2 0.0 6.4 6 3 0 6 6 6 0 Serglycin SKIP_SNW PF02731.10 OAJ25395.1 - 9.3e-65 216.8 1.8 9.3e-65 216.8 1.2 2.1 3 0 0 3 3 3 1 SKIP/SNW domain FAD_binding_2 PF00890.19 OAJ25396.1 - 1.5e-86 290.8 0.1 1.7e-86 290.6 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAJ25396.1 - 1.3e-08 34.7 0.3 7.7e-08 32.2 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAJ25396.1 - 1.5e-08 34.7 0.0 5.8e-05 23.0 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ25396.1 - 4.5e-07 29.1 0.1 2.8e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAJ25396.1 - 1.3e-06 27.7 0.1 4.9e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 OAJ25396.1 - 4.1e-06 27.1 1.8 8.5e-05 22.8 0.3 3.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ25396.1 - 9.4e-05 21.0 0.1 9.4e-05 21.0 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.2 OAJ25396.1 - 0.0011 18.1 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAJ25396.1 - 0.0012 17.8 0.6 0.0019 17.1 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 OAJ25396.1 - 0.0012 17.7 0.6 0.0012 17.7 0.4 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 OAJ25396.1 - 0.0016 18.1 0.3 0.0038 17.0 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 OAJ25396.1 - 0.0037 16.4 1.1 0.0079 15.3 0.1 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 OAJ25396.1 - 0.0045 17.0 0.4 0.01 15.9 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 OAJ25396.1 - 0.0081 16.4 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 OAJ25396.1 - 0.012 15.2 3.0 0.012 15.2 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 OAJ25396.1 - 0.15 11.4 0.1 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ribosomal_S5 PF00333.15 OAJ25397.1 - 5.3e-15 54.9 1.3 1.1e-14 53.8 0.9 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 OAJ25397.1 - 3.9e-14 51.6 0.0 9.5e-14 50.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain PRP1_N PF06424.7 OAJ25397.1 - 0.074 13.3 2.9 7.6 6.8 0.1 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal MRP PF09387.5 OAJ25397.1 - 0.081 12.6 1.3 0.13 11.9 0.9 1.3 1 0 0 1 1 1 0 Mitochondrial RNA binding protein MRP Pex14_N PF04695.8 OAJ25397.1 - 0.21 11.6 6.3 0.35 10.9 4.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Herpes_capsid PF06112.6 OAJ25397.1 - 2.4 8.2 20.2 6.1 6.8 14.0 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF566 PF04484.7 OAJ25397.1 - 3.3 7.1 14.4 5.3 6.4 10.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Period_C PF12114.3 OAJ25397.1 - 8.3 5.9 14.2 14 5.2 9.8 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Rsa3 PF14615.1 OAJ25398.1 - 0.00078 18.6 0.0 0.0042 16.3 0.0 2.0 1 1 0 1 1 1 1 Ribosome-assembly protein 3 DUF3322 PF11795.3 OAJ25398.1 - 0.011 15.4 2.3 0.016 14.8 1.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) TPR_11 PF13414.1 OAJ25400.1 - 1e-27 95.5 3.5 1e-12 47.4 0.0 3.7 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 OAJ25400.1 - 4.2e-19 67.2 0.1 4.1e-05 23.0 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ25400.1 - 1.2e-14 52.9 1.4 0.00063 19.4 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ25400.1 - 4e-13 48.4 1.5 0.012 15.7 0.0 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ25400.1 - 1.5e-10 40.8 4.3 8.6e-06 25.6 0.0 4.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ25400.1 - 3.1e-10 39.0 0.1 0.02 14.6 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ25400.1 - 1.2e-08 34.8 13.4 0.012 16.1 0.0 7.1 5 2 3 8 8 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ25400.1 - 3.8e-07 30.6 0.0 0.00015 22.3 0.0 7.1 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ25400.1 - 8.6e-07 29.2 3.5 0.28 11.5 0.0 4.8 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ25400.1 - 1.6e-06 27.4 0.1 0.25 11.1 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ25400.1 - 0.00019 21.1 4.2 1.4 8.8 0.0 4.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ25400.1 - 0.0095 16.0 9.1 0.075 13.1 0.4 4.9 3 2 1 5 5 5 2 Tetratricopeptide repeat 2OG-FeII_Oxy_2 PF13532.1 OAJ25401.1 - 6.1e-15 55.5 0.0 8.9e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ25401.1 - 2.6e-06 27.6 0.0 4.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RVT_1 PF00078.22 OAJ25402.1 - 1.5e-14 53.8 0.0 2.7e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) F-box PF00646.28 OAJ25403.1 - 4.4e-08 32.5 0.0 9.8e-08 31.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ25403.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 F-box-like Nucleoplasmin PF03066.10 OAJ25403.1 - 0.66 9.4 2.7 1 8.8 1.8 1.2 1 0 0 1 1 1 0 Nucleoplasmin Pkinase PF00069.20 OAJ25404.1 - 2.3e-58 197.3 0.0 1.4e-57 194.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ25404.1 - 1.1e-25 90.2 0.0 1.6e-24 86.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ25404.1 - 1.2e-08 34.2 0.0 2.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ25404.1 - 0.015 15.0 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ25404.1 - 0.037 12.8 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 F-box PF00646.28 OAJ25406.1 - 0.0021 17.6 0.9 0.004 16.7 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 OAJ25406.1 - 0.0046 16.6 0.1 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 F-box-like domain EF-hand_6 PF13405.1 OAJ25409.1 - 2.2e-09 36.3 2.4 0.00011 21.8 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 OAJ25409.1 - 1.4e-08 34.7 1.3 9.8e-07 28.8 0.9 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 OAJ25409.1 - 5.8e-08 31.4 5.9 0.00029 19.9 0.2 3.3 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 OAJ25409.1 - 0.0025 17.0 2.9 0.03 13.6 0.4 2.6 2 0 0 2 2 2 1 EF hand PRTP PF01366.13 OAJ25409.1 - 0.19 9.6 0.0 0.22 9.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein EF-hand_8 PF13833.1 OAJ25409.1 - 0.34 10.5 3.2 15 5.3 0.0 3.1 2 1 1 3 3 3 0 EF-hand domain pair Nucleos_tra2_C PF07662.8 OAJ25410.1 - 4.9e-69 232.0 0.5 1e-68 230.9 0.4 1.6 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 OAJ25410.1 - 9.8e-13 48.2 3.9 9.8e-13 48.2 2.7 3.4 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 OAJ25410.1 - 2.2 8.2 16.2 3.5 7.5 5.9 3.4 2 1 0 2 2 2 0 Nucleoside recognition zf-DHHC PF01529.15 OAJ25411.1 - 3.6e-30 104.6 0.2 1.1e-29 103.0 0.1 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase ATE_C PF04377.10 OAJ25412.1 - 7.6e-43 145.6 0.1 1.2e-42 145.0 0.1 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 OAJ25412.1 - 4.2e-23 80.9 0.2 7.5e-23 80.1 0.2 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Glyco_transf_8 PF01501.15 OAJ25413.1 - 2.7e-24 85.8 0.0 1.7e-23 83.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 8 Abhydrolase_6 PF12697.2 OAJ25413.1 - 2.5e-21 76.6 0.0 1.3e-20 74.2 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ25413.1 - 1.5e-15 57.2 0.0 3.5e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ25413.1 - 2.1e-14 53.1 0.0 4.8e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 OAJ25413.1 - 0.0002 20.9 0.0 0.00099 18.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAJ25413.1 - 0.00058 19.1 0.1 0.14 11.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Mannosyl_trans3 PF11051.3 OAJ25413.1 - 0.0037 16.6 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Esterase PF00756.15 OAJ25413.1 - 0.0038 16.6 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 OAJ25413.1 - 0.033 13.2 0.0 0.08 12.0 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) AXE1 PF05448.7 OAJ25413.1 - 0.041 12.3 0.1 0.34 9.3 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) LCAT PF02450.10 OAJ25413.1 - 0.062 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase tRNA-synt_2 PF00152.15 OAJ25414.1 - 3.9e-69 232.9 0.0 6e-69 232.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAJ25414.1 - 4.4e-11 42.4 0.0 8.2e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RRP7 PF12923.2 OAJ25414.1 - 0.021 14.8 3.5 0.047 13.7 2.4 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) tRNA-synt_2 PF00152.15 OAJ25415.1 - 4.7e-29 101.2 0.3 6.7e-29 100.7 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAJ25415.1 - 1.3e-05 24.9 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ATP11 PF06644.6 OAJ25416.1 - 3.1e-63 213.7 0.0 7.3e-63 212.5 0.0 1.6 1 1 0 1 1 1 1 ATP11 protein CDC27 PF09507.5 OAJ25416.1 - 0.058 12.6 10.9 0.078 12.1 7.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MHC2-interact PF09307.5 OAJ25416.1 - 0.06 13.1 2.3 1.1 9.0 0.3 2.8 3 1 0 3 3 3 0 CLIP, MHC2 interacting PepSY_2 PF13670.1 OAJ25416.1 - 1 9.3 6.2 0.29 11.0 0.6 2.5 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain FUSC PF04632.7 OAJ25416.1 - 2.1 6.7 6.9 2.9 6.2 4.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family SR-25 PF10500.4 OAJ25416.1 - 6.1 6.2 18.5 6.6 6.1 3.3 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein PUF PF00806.14 OAJ25428.1 - 4.9e-58 189.4 2.2 4.1e-10 38.5 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Fer2_3 PF13085.1 OAJ25429.1 - 1e-31 109.0 0.0 1.6e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 OAJ25429.1 - 7.7e-10 38.9 6.2 7.7e-10 38.9 4.3 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 OAJ25429.1 - 2.7e-09 36.8 5.0 2.7e-09 36.8 3.5 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 OAJ25429.1 - 0.00014 22.1 3.1 0.00014 22.1 2.1 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 OAJ25429.1 - 0.00021 21.5 5.4 0.05 13.8 0.4 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 OAJ25429.1 - 0.00026 20.7 4.5 0.00026 20.7 3.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 OAJ25429.1 - 0.011 15.4 1.4 0.011 15.4 1.0 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 OAJ25429.1 - 0.02 15.2 6.5 0.02 15.2 4.5 2.6 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 OAJ25429.1 - 0.17 12.4 5.2 1.8 9.1 0.2 2.9 3 0 0 3 3 3 0 4Fe-4S single cluster domain DNA_pol3_tau_4 PF12168.3 OAJ25429.1 - 1.1 9.7 4.0 1.5 9.2 0.8 2.3 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Glyco_hydro_45 PF02015.11 OAJ25430.1 - 1.3e-50 172.2 7.9 1.5e-50 172.0 5.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Glyco_hydro_45 PF02015.11 OAJ25431.1 - 4.1e-29 102.0 6.1 5.4e-29 101.6 4.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 RRM_1 PF00076.17 OAJ25432.1 - 1.3e-10 40.7 0.0 3.5e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ25432.1 - 1.8e-08 34.2 0.0 2.7e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ25432.1 - 1.9e-05 24.3 0.0 3.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tetraspannin PF00335.15 OAJ25433.1 - 2.3e-17 63.0 8.5 2.9e-17 62.6 5.9 1.1 1 0 0 1 1 1 1 Tetraspanin family YL1_C PF08265.6 OAJ25434.1 - 1.7e-13 49.8 0.3 2.9e-13 49.1 0.2 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain tRNA-synt_2 PF00152.15 OAJ25435.1 - 7.1e-59 199.2 0.0 1.7e-56 191.4 0.0 3.1 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAJ25435.1 - 5.5e-05 22.9 0.0 0.00024 20.8 0.0 2.0 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2428 PF10350.4 OAJ25436.1 - 9.2e-45 152.6 1.3 2.1e-44 151.5 0.2 2.3 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 OAJ25436.1 - 0.0012 18.7 4.9 12 6.3 0.1 5.0 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 OAJ25436.1 - 0.0026 17.9 1.2 0.0026 17.9 0.8 3.8 4 0 0 4 4 4 1 HEAT repeats Nairo_nucleo PF02477.10 OAJ25436.1 - 0.17 10.5 0.1 0.61 8.7 0.0 1.8 2 0 0 2 2 2 0 Nucleocapsid N protein HEAT_EZ PF13513.1 OAJ25436.1 - 1 9.9 11.5 1.2 9.6 0.2 5.2 5 0 0 5 5 5 0 HEAT-like repeat SRP14 PF02290.10 OAJ25437.1 - 1.6e-13 50.3 0.1 3.7e-12 46.0 0.0 2.8 2 1 0 2 2 2 1 Signal recognition particle 14kD protein DUF4200 PF13863.1 OAJ25437.1 - 0.58 10.1 9.6 3.8 7.4 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) HECT_2 PF09814.4 OAJ25439.1 - 3.3e-17 62.2 0.0 3.7e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Bromo_TP PF07524.8 OAJ25440.1 - 0.00085 19.0 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated YTH PF04146.10 OAJ25441.1 - 1.8e-41 140.9 0.0 2.8e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain Mem_trans PF03547.13 OAJ25442.1 - 1.9e-41 141.6 1.1 1.3e-37 129.0 0.0 2.3 2 1 0 2 2 2 2 Membrane transport protein dCMP_cyt_deam_1 PF00383.17 OAJ25443.1 - 2.4e-14 52.8 0.2 3.8e-14 52.1 0.1 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 OAJ25443.1 - 5.1e-12 45.8 1.6 1.8e-10 40.9 0.2 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 OAJ25443.1 - 0.00024 20.5 2.1 0.02 14.2 0.0 2.2 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Thiolase_N PF00108.18 OAJ25444.1 - 1.9e-67 227.0 0.0 9.6e-67 224.7 0.0 2.0 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAJ25444.1 - 1.4e-44 150.4 0.3 3.4e-44 149.1 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 OAJ25444.1 - 1.3e-05 24.8 0.2 3.3e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 OAJ25444.1 - 0.089 12.4 0.2 3.9 7.1 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III LIP PF03583.9 OAJ25445.1 - 1.7e-55 188.2 0.1 2.4e-55 187.7 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 OAJ25445.1 - 2.5e-08 34.0 0.5 4.9e-08 33.1 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ25445.1 - 5.3e-08 32.7 0.1 1e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ25445.1 - 0.035 13.3 0.1 8.5 5.5 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Cutinase PF01083.17 OAJ25445.1 - 0.048 13.3 0.3 0.097 12.3 0.0 1.6 2 0 0 2 2 2 0 Cutinase Abhydrolase_1 PF00561.15 OAJ25445.1 - 0.049 13.1 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 OAJ25446.1 - 1.1e-59 201.4 0.0 1.5e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 OAJ25446.1 - 2.1e-13 50.2 0.0 2.8e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ25446.1 - 3.8e-10 40.0 0.0 8.2e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ25446.1 - 0.0013 18.3 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 OAJ25446.1 - 0.011 15.0 0.0 0.026 13.7 0.0 1.8 1 1 1 2 2 2 0 Esterase PHB depolymerase Cutinase PF01083.17 OAJ25446.1 - 0.022 14.5 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase FSH1 PF03959.8 OAJ25446.1 - 0.027 13.8 0.0 0.15 11.4 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Lipase_3 PF01764.20 OAJ25446.1 - 0.094 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) CK_II_beta PF01214.13 OAJ25447.1 - 1.2e-72 243.2 0.0 1.5e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Ded_cyto PF06920.8 OAJ25449.1 - 1.4e-36 125.4 0.2 1.4e-35 122.1 0.0 2.4 2 0 0 2 2 2 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 OAJ25449.1 - 1.1e-31 109.8 0.0 3e-21 75.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins ELFV_dehydrog PF00208.16 OAJ25451.1 - 3e-43 148.1 1.0 3.7e-43 147.8 0.7 1.0 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 OAJ25451.1 - 8.9e-07 28.5 0.0 2.3e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 OAJ25451.1 - 0.086 13.0 0.1 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding BPL_LplA_LipB PF03099.14 OAJ25459.1 - 0.00013 21.9 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family SBDS_C PF09377.5 OAJ25460.1 - 2.7e-43 146.6 0.8 4.3e-43 145.9 0.5 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 OAJ25460.1 - 3.5e-31 106.8 1.0 5.5e-31 106.2 0.3 1.7 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein 2-Hacid_dh_C PF02826.14 OAJ25460.1 - 0.087 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Nop52 PF05997.7 OAJ25461.1 - 1.6e-50 171.5 0.0 4.6e-44 150.4 0.0 2.2 2 0 0 2 2 2 2 Nucleolar protein,Nop52 TFIIF_alpha PF05793.7 OAJ25461.1 - 5 5.3 20.5 0.19 10.0 9.1 1.9 1 1 1 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HMG_box PF00505.14 OAJ25462.1 - 1.7e-18 66.6 6.6 3.1e-10 40.1 1.4 3.5 3 1 1 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ25462.1 - 3.6e-10 40.0 4.2 3.7e-07 30.4 0.1 3.4 3 1 0 3 3 3 2 HMG-box domain DUF3106 PF11304.3 OAJ25462.1 - 0.61 10.5 13.0 0.48 10.8 1.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) Med3 PF11593.3 OAJ25462.1 - 2.6 7.2 27.1 5.2 6.2 18.8 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cation_efflux PF01545.16 OAJ25463.1 - 8.1e-30 103.8 4.8 9.7e-30 103.6 3.3 1.1 1 0 0 1 1 1 1 Cation efflux family Ras PF00071.17 OAJ25464.1 - 8.3e-28 96.8 0.0 1.4e-26 92.8 0.0 2.1 2 0 0 2 2 2 1 Ras family Miro PF08477.8 OAJ25464.1 - 1.4e-09 38.5 0.0 2.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ25464.1 - 0.00014 21.1 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ25464.1 - 0.001 18.2 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Nucleoplasmin PF03066.10 OAJ25464.1 - 5 6.6 16.7 0.77 9.2 1.2 3.6 4 0 0 4 4 4 0 Nucleoplasmin DNA_binding_1 PF01035.15 OAJ25465.1 - 2.1e-06 27.3 0.0 3.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Actin PF00022.14 OAJ25466.1 - 2.5e-23 82.1 0.0 1.4e-20 73.0 0.0 3.1 3 1 0 3 3 3 3 Actin Myb_DNA-binding PF00249.26 OAJ25467.1 - 1.3e-28 98.7 1.0 5.3e-16 58.4 1.0 3.8 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ25467.1 - 2.7e-25 88.2 0.1 3.9e-16 58.8 0.1 4.1 1 1 3 4 4 4 3 Myb-like DNA-binding domain SecE PF00584.15 OAJ25468.1 - 1.2e-13 50.4 0.0 1.3e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CD24 PF14984.1 OAJ25469.1 - 5.5 6.8 12.9 4.2 7.2 6.4 2.7 3 0 0 3 3 3 0 CD24 protein ECH PF00378.15 OAJ25470.1 - 2.3e-40 138.2 0.2 5e-40 137.1 0.1 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Rop-like PF05082.8 OAJ25470.1 - 0.065 12.7 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 Rop-like DUF2910 PF11139.3 OAJ25470.1 - 0.073 12.1 0.4 3.9 6.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2910) PNP_UDP_1 PF01048.15 OAJ25471.1 - 2.1e-23 82.5 0.1 2.5e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Csm1 PF12539.3 OAJ25472.1 - 1.7e-06 28.4 0.0 1.2e-05 25.7 0.0 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 AIP3 PF03915.8 OAJ25472.1 - 0.29 10.0 12.3 0.12 11.1 6.8 1.6 1 1 0 1 1 1 0 Actin interacting protein 3 HAUS6_N PF14661.1 OAJ25472.1 - 0.35 10.1 17.4 0.069 12.4 2.6 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus IncA PF04156.9 OAJ25472.1 - 0.7 9.4 19.7 0.61 9.6 4.9 2.2 2 0 0 2 2 2 0 IncA protein Fib_alpha PF08702.5 OAJ25472.1 - 0.92 9.6 7.8 0.93 9.6 1.3 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RTBV_P46 PF06216.6 OAJ25472.1 - 1.6 7.4 5.8 1.2 7.9 0.3 2.1 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein Tropomyosin PF00261.15 OAJ25472.1 - 1.8 7.5 29.6 2.1 7.3 2.9 3.1 2 1 1 3 3 3 0 Tropomyosin DUF1515 PF07439.6 OAJ25472.1 - 3.1 7.6 10.2 1.3 8.8 1.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Dsh_C PF12316.3 OAJ25472.1 - 3.6 7.6 19.1 2.4 8.2 3.4 2.4 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Ax_dynein_light PF10211.4 OAJ25472.1 - 6.9 6.4 22.3 2.4 7.9 3.2 2.8 2 1 1 3 3 3 0 Axonemal dynein light chain TCTP PF00838.12 OAJ25473.1 - 5.1e-63 211.9 0.4 5.7e-63 211.7 0.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Methyltransf_16 PF10294.4 OAJ25474.1 - 3.9e-15 55.7 0.0 7.7e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 OAJ25474.1 - 0.016 15.8 0.1 0.072 13.6 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ25474.1 - 0.079 13.3 0.0 0.22 11.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ25474.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S8e PF01201.17 OAJ25475.1 - 1.1e-49 167.9 1.6 1.4e-49 167.6 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SPO22 PF08631.5 OAJ25476.1 - 3.5e-06 26.3 0.1 3.5e-06 26.3 0.1 3.2 3 1 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_6 PF13174.1 OAJ25476.1 - 1.6 9.3 9.2 7.3 7.2 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.24 OAJ25477.1 - 1.5e-41 141.7 0.0 3.6e-41 140.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ25477.1 - 2.9e-26 91.1 0.0 2.4e-25 88.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Borrelia_P83 PF05262.6 OAJ25477.1 - 0.036 12.3 13.4 0.045 12.0 9.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC27 PF09507.5 OAJ25477.1 - 2.5 7.2 26.1 4 6.5 18.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 KH_1 PF00013.24 OAJ25478.1 - 2.8e-05 23.6 0.1 7.9e-05 22.2 0.1 1.7 2 0 0 2 2 2 1 KH domain RAP1 PF07218.6 OAJ25478.1 - 0.0015 16.6 1.4 0.0022 16.1 1.0 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) DNA_primase_lrg PF04104.9 OAJ25479.1 - 4.7e-78 262.0 0.0 7e-78 261.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Pro_isomerase PF00160.16 OAJ25480.1 - 1.1e-37 129.6 0.0 7.1e-37 127.0 0.0 2.1 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.1 OAJ25480.1 - 0.018 15.2 0.1 0.018 15.2 0.1 3.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4604) Aminotran_1_2 PF00155.16 OAJ25481.1 - 1.8e-20 73.1 0.0 4.3e-20 71.9 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 OAJ25481.1 - 0.0001 20.7 0.0 0.00021 19.7 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3153 PF11353.3 OAJ25481.1 - 0.041 13.3 0.0 0.088 12.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) VWA PF00092.23 OAJ25484.1 - 0.0032 17.2 0.1 0.0051 16.5 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyco_hydro_92 PF07971.7 OAJ25485.1 - 8.2e-109 364.5 0.0 1.2e-108 363.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Snf7 PF03357.16 OAJ25487.1 - 1.6e-45 154.5 12.2 1.9e-45 154.3 8.5 1.0 1 0 0 1 1 1 1 Snf7 Mod_r PF07200.8 OAJ25487.1 - 0.004 17.0 7.2 0.0044 16.9 3.6 1.8 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Soyouz_module PF14313.1 OAJ25487.1 - 0.021 14.3 0.1 1.2 8.7 0.0 2.9 3 0 0 3 3 3 0 N-terminal region of Paramyxovirinae phosphoprotein (P) NuA4 PF09340.5 OAJ25487.1 - 0.062 12.9 0.6 0.062 12.9 0.4 2.0 2 1 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DMPK_coil PF08826.5 OAJ25487.1 - 0.089 12.7 0.3 0.089 12.7 0.2 3.6 4 0 0 4 4 4 0 DMPK coiled coil domain like DUF3091 PF11291.3 OAJ25487.1 - 0.12 12.3 1.1 0.34 10.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) EURL PF06937.6 OAJ25487.1 - 0.12 11.7 3.3 0.15 11.4 2.3 1.1 1 0 0 1 1 1 0 EURL protein DUF4559 PF15112.1 OAJ25487.1 - 0.19 10.8 7.8 0.24 10.5 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Tweety PF04906.8 OAJ25487.1 - 0.42 8.9 2.2 0.39 9.0 0.8 1.4 1 1 0 1 1 1 0 Tweety FlxA PF14282.1 OAJ25487.1 - 0.61 10.0 12.0 1.1 9.2 4.5 2.3 1 1 1 2 2 2 0 FlxA-like protein Prefoldin_2 PF01920.15 OAJ25487.1 - 0.82 9.4 16.9 5.1 6.9 0.6 3.6 2 1 1 3 3 3 0 Prefoldin subunit DUF2730 PF10805.3 OAJ25487.1 - 0.99 9.1 6.4 4.6 7.0 0.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) DUF848 PF05852.6 OAJ25487.1 - 1.7 8.5 11.4 0.95 9.3 5.7 2.1 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) NPV_P10 PF05531.7 OAJ25487.1 - 2.2 8.5 6.7 1.7 8.9 0.7 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 OAJ25487.1 - 2.5 5.8 9.7 5.5 4.7 3.0 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 OAJ25487.1 - 3.5 5.9 9.3 1.4 7.2 3.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) SseC PF04888.7 OAJ25487.1 - 4.7 6.4 9.6 0.6 9.3 1.9 2.4 2 1 0 2 2 2 0 Secretion system effector C (SseC) like family THP2 PF09432.5 OAJ25487.1 - 4.9 7.0 7.3 3.3 7.5 1.9 2.5 1 1 2 3 3 3 0 Tho complex subunit THP2 Mnd1 PF03962.10 OAJ25487.1 - 5.3 6.6 13.9 18 4.9 0.8 2.2 1 1 1 2 2 2 0 Mnd1 family EMP24_GP25L PF01105.19 OAJ25487.1 - 5.5 6.6 6.8 8.1 6.1 0.0 2.8 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Nse4_C PF08743.5 OAJ25488.1 - 1.4e-26 92.2 0.1 3.6e-26 91.0 0.1 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 OAJ25488.1 - 8.2e-09 35.1 0.5 1.7e-08 34.1 0.3 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE ADH_N PF08240.7 OAJ25489.1 - 5.9e-27 93.5 1.9 6.5e-27 93.4 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ25489.1 - 9.7e-24 83.3 0.4 9.7e-24 83.3 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ25489.1 - 0.0044 17.9 1.3 0.0082 17.0 0.7 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase mono-CXXC PF15626.1 OAJ25489.1 - 0.047 13.6 0.7 0.14 12.0 0.5 1.8 1 0 0 1 1 1 0 single CXXC unit ACP_syn_III_C PF08541.5 OAJ25489.1 - 0.066 13.2 0.5 0.46 10.5 0.1 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Totivirus_coat PF05518.6 OAJ25490.1 - 5.6 4.6 16.0 7.8 4.1 11.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein Mito_carr PF00153.22 OAJ25496.1 - 3.4e-69 228.6 0.9 5.4e-24 83.7 0.0 3.7 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIA PF03153.8 OAJ25496.1 - 2.4 7.9 12.7 4 7.2 8.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM196 PF15265.1 OAJ25496.1 - 5.5 6.1 13.1 8.2 5.5 9.1 1.1 1 0 0 1 1 1 0 FAM196 family DUF572 PF04502.8 OAJ25497.1 - 2.5e-88 296.4 0.1 3.3e-88 296.0 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) COG5 PF10392.4 OAJ25497.1 - 0.041 13.8 0.6 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 HrpA_pilin PF09589.5 OAJ25497.1 - 0.095 13.1 0.2 0.095 13.1 0.1 2.1 2 1 0 2 2 2 0 HrpA pilus formation protein DUF866 PF05907.8 OAJ25497.1 - 0.13 11.7 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Benyvirus_14KDa PF07255.6 OAJ25497.1 - 0.14 12.0 0.2 0.35 10.7 0.1 1.6 1 1 0 1 1 1 0 Benyvirus 14KDa protein Lar_restr_allev PF14354.1 OAJ25497.1 - 0.18 12.0 0.9 2.7 8.3 0.6 2.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF2365 PF10157.4 OAJ25497.1 - 0.24 11.2 1.6 12 5.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) peroxidase PF00141.18 OAJ25499.1 - 8.5e-49 166.0 0.0 1.5e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 Peroxidase DUF2433 PF10360.4 OAJ25500.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) Cut8_N PF14482.1 OAJ25501.1 - 0.0016 18.3 2.1 0.0016 18.3 1.5 2.8 4 0 0 4 4 4 1 Cut8 proteasome-binding domain RPA_interact_C PF14768.1 OAJ25501.1 - 0.0088 16.4 0.2 0.045 14.1 0.0 2.1 2 0 0 2 2 2 1 Replication protein A interacting C-terminal Zip PF02535.17 OAJ25501.1 - 0.44 9.5 3.3 0.45 9.4 2.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Hexapep PF00132.19 OAJ25502.1 - 1e-13 50.0 6.4 6.3e-11 41.2 3.0 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 OAJ25502.1 - 6.1e-13 48.0 7.1 1.4e-11 43.7 2.5 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 OAJ25502.1 - 3.6e-08 33.3 0.0 1e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Maltose acetyltransferase Acyl_transf_1 PF00698.16 OAJ25503.1 - 8.1e-12 45.0 0.1 2.9e-06 26.8 0.0 2.9 1 1 1 2 2 2 2 Acyl transferase domain Hexapep_2 PF14602.1 OAJ25504.1 - 1.4e-12 46.8 3.3 8.5e-11 41.2 1.2 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 OAJ25504.1 - 3e-12 45.4 2.0 4.6e-09 35.3 1.0 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 OAJ25504.1 - 9.3e-10 38.3 0.1 2.3e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Maltose acetyltransferase Fungal_trans PF04082.13 OAJ25505.1 - 3.6e-07 29.3 0.0 6.5e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ25505.1 - 2e-06 27.5 10.4 3.2e-06 26.9 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 OAJ25506.1 - 4.1e-73 246.4 0.0 9.7e-71 238.6 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 PspB PF06667.7 OAJ25506.1 - 0.06 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Phage shock protein B Co_AT_N PF12557.3 OAJ25506.1 - 0.066 13.1 0.2 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal ketoacyl-synt PF00109.21 OAJ25508.1 - 1.3e-76 257.5 0.0 3.9e-76 255.8 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 OAJ25508.1 - 6.7e-47 160.3 0.0 1.4e-43 149.4 0.0 3.7 3 1 1 4 4 4 2 Acyl transferase domain Ketoacyl-synt_C PF02801.17 OAJ25508.1 - 4.7e-33 113.5 0.9 1e-32 112.5 0.6 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 OAJ25508.1 - 1.2e-27 96.8 0.0 2.4e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 OAJ25508.1 - 8.3e-27 94.8 0.1 8.5e-26 91.5 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 OAJ25508.1 - 4.4e-15 55.6 3.1 1.1e-06 28.7 0.2 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 OAJ25508.1 - 9.9e-11 41.9 2.3 6.5e-09 36.0 0.0 3.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ25508.1 - 2.5e-09 37.0 0.3 0.00012 21.8 0.0 3.9 4 0 0 4 4 4 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 OAJ25508.1 - 2.7e-05 23.2 0.1 8.2e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_1 PF00561.15 OAJ25508.1 - 0.056 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold SUR7 PF06687.7 OAJ25509.1 - 8.7e-07 28.7 4.4 1.9e-06 27.6 3.1 1.6 1 1 0 1 1 1 1 SUR7/PalI family Cytochrom_B_N PF00033.14 OAJ25509.1 - 0.014 14.7 0.6 0.014 14.7 0.4 2.2 2 1 1 3 3 3 0 Cytochrome b(N-terminal)/b6/petB HCMV_UL139 PF12507.3 OAJ25509.1 - 0.099 12.8 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein FixQ PF05545.6 OAJ25509.1 - 0.1 12.2 0.4 0.1 12.2 0.2 2.8 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ Uso1_p115_head PF04869.9 OAJ25510.1 - 6.3e-32 110.5 0.0 3.7e-30 104.7 0.0 3.4 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region WEMBL PF05701.6 OAJ25510.1 - 0.0019 16.7 39.2 0.0019 16.7 27.2 2.1 2 0 0 2 2 2 1 Weak chloroplast movement under blue light Cep57_MT_bd PF06657.8 OAJ25510.1 - 7.9 6.5 23.3 0.22 11.4 0.4 4.2 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 RabGAP-TBC PF00566.13 OAJ25511.1 - 2.4e-48 164.4 0.0 3.2e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Methyltransf_2 PF00891.13 OAJ25512.1 - 6.9e-32 110.5 0.0 1e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 OAJ25512.1 - 0.0006 20.3 0.0 0.0015 19.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain HTH_IclR PF09339.5 OAJ25512.1 - 0.0075 15.8 0.3 2.2 7.9 0.0 2.7 2 0 0 2 2 2 2 IclR helix-turn-helix domain MTS PF05175.9 OAJ25512.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF3115 PF11312.3 OAJ25512.1 - 0.22 10.3 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) Methyltransf_2 PF00891.13 OAJ25513.1 - 1e-05 24.8 0.0 1.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Lig_chan-Glu_bd PF10613.4 OAJ25513.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site GSDH PF07995.6 OAJ25514.1 - 2.7e-06 26.7 0.5 1.2e-05 24.6 0.2 2.3 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase Aldo_ket_red PF00248.16 OAJ25515.1 - 7.3e-45 152.9 0.0 8.4e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Myb_DNA-binding PF00249.26 OAJ25516.1 - 3.6e-27 94.1 4.7 6.7e-09 35.6 0.0 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ25516.1 - 4.7e-25 87.4 4.8 3.2e-10 39.9 0.0 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain SprA-related PF12118.3 OAJ25516.1 - 0.0024 17.2 28.2 0.0098 15.2 8.4 2.4 2 0 0 2 2 2 2 SprA-related family zf-DHHC PF01529.15 OAJ25516.1 - 0.016 14.6 3.3 0.079 12.3 0.3 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Spt20 PF12090.3 OAJ25516.1 - 0.037 13.3 17.3 0.17 11.2 5.4 2.3 2 0 0 2 2 2 0 Spt20 family BRF1 PF07741.8 OAJ25516.1 - 0.072 13.3 9.4 0.46 10.7 1.1 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain CDK5_activator PF03261.10 OAJ25516.1 - 0.089 12.1 24.8 0.025 13.9 3.7 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein Tim54 PF11711.3 OAJ25516.1 - 0.14 10.6 13.1 0.3 9.6 1.2 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF4011 PF13195.1 OAJ25516.1 - 0.23 11.4 5.1 0.88 9.5 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) Suf PF05843.9 OAJ25516.1 - 0.35 10.5 22.6 0.45 10.1 7.1 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4557 PF15101.1 OAJ25516.1 - 0.41 10.4 25.6 0.39 10.5 8.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Plasmodium_Vir PF05795.6 OAJ25516.1 - 0.48 9.5 7.9 3.4 6.7 1.1 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein FimP PF09766.4 OAJ25516.1 - 0.59 9.1 26.1 0.02 13.9 6.9 2.1 2 0 0 2 2 2 0 Fms-interacting protein Dehydrin PF00257.14 OAJ25516.1 - 0.59 10.4 13.6 7.2 6.9 0.2 2.3 2 0 0 2 2 2 0 Dehydrin Apc15p PF05841.6 OAJ25516.1 - 0.68 10.6 26.3 1.5 9.5 8.3 2.6 2 0 0 2 2 2 0 Apc15p protein Band_3_cyto PF07565.8 OAJ25516.1 - 0.78 9.2 12.9 2.7 7.4 4.2 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF4175 PF13779.1 OAJ25516.1 - 0.78 7.3 38.4 0.33 8.5 16.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DUF3408 PF11888.3 OAJ25516.1 - 1.1 9.1 18.5 0.43 10.5 4.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) AAA_23 PF13476.1 OAJ25516.1 - 1.7 8.9 10.1 0.42 10.9 1.8 2.1 2 0 0 2 2 2 0 AAA domain DUF2413 PF10310.4 OAJ25516.1 - 2.4 6.8 22.8 0.68 8.6 5.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) RR_TM4-6 PF06459.7 OAJ25516.1 - 2.5 7.9 13.2 2 8.2 3.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Serinc PF03348.10 OAJ25516.1 - 4.2 5.9 12.5 0.53 8.9 2.8 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) Gti1_Pac2 PF09729.4 OAJ25516.1 - 6.4 6.6 11.4 4.8 7.0 2.9 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family FAM60A PF15396.1 OAJ25516.1 - 8.3 6.0 14.1 7.1 6.3 3.2 2.4 2 0 0 2 2 2 0 Protein Family FAM60A Ctr PF04145.10 OAJ25516.1 - 9.4 6.2 10.3 9.9 6.2 2.3 2.4 2 0 0 2 2 2 0 Ctr copper transporter family adh_short PF00106.20 OAJ25518.1 - 3.6e-21 75.7 3.7 7.2e-21 74.8 2.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ25518.1 - 1e-13 51.6 1.0 1.8e-13 50.8 0.7 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ25518.1 - 3e-09 36.7 0.7 4.5e-09 36.2 0.5 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAJ25518.1 - 6.2e-07 29.0 0.1 9.2e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ25518.1 - 2e-06 27.9 1.4 5.2e-06 26.5 1.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 OAJ25518.1 - 0.022 13.9 0.5 0.039 13.1 0.3 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 OAJ25518.1 - 0.046 12.6 0.1 0.12 11.2 0.1 1.9 2 1 0 2 2 2 0 RmlD substrate binding domain TrkA_N PF02254.13 OAJ25518.1 - 0.076 13.0 0.5 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain 3Beta_HSD PF01073.14 OAJ25518.1 - 0.09 11.4 0.2 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FAD_binding_3 PF01494.14 OAJ25519.1 - 7.4e-61 206.1 0.0 9.6e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAJ25519.1 - 2.2e-05 24.4 0.1 7.1e-05 22.7 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ25519.1 - 6.1e-05 23.3 0.0 0.0003 21.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ25519.1 - 0.0001 21.3 0.7 0.008 15.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAJ25519.1 - 0.00025 20.1 0.0 0.0004 19.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 OAJ25519.1 - 0.00076 19.4 0.2 0.002 18.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAJ25519.1 - 0.00099 18.1 0.2 0.0016 17.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 OAJ25519.1 - 0.0025 16.7 0.3 0.0045 15.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 OAJ25519.1 - 0.0041 15.6 0.4 0.0065 14.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 OAJ25519.1 - 0.027 13.3 0.4 0.041 12.7 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 OAJ25519.1 - 0.036 14.1 0.2 0.085 12.9 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 OAJ25519.1 - 0.071 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 OAJ25519.1 - 0.073 12.8 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 ThiF family Myb_DNA-binding PF00249.26 OAJ25520.1 - 3.1e-26 91.1 4.0 5.9e-09 35.8 0.6 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ25520.1 - 1.3e-25 89.2 4.2 7.3e-11 42.0 0.0 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain BRF1 PF07741.8 OAJ25520.1 - 1.1 9.5 6.5 6.8 6.9 1.4 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Syntaxin-18_N PF10496.4 OAJ25521.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus SnoaL PF07366.7 OAJ25521.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 OAJ25521.1 - 0.15 12.4 0.0 0.17 12.3 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain CDC37_N PF03234.9 OAJ25527.1 - 2e-39 135.7 1.2 6.2e-38 130.8 0.8 2.5 1 1 0 1 1 1 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 OAJ25527.1 - 3.6e-21 75.4 0.7 5.4e-17 61.8 0.0 2.6 2 0 0 2 2 2 2 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 OAJ25527.1 - 5.8e-14 51.7 0.1 2.3e-13 49.8 0.0 2.0 1 0 0 1 1 1 1 Cdc37 C terminal domain DivIC PF04977.10 OAJ25528.1 - 6 6.4 6.4 11 5.5 4.4 1.5 1 1 0 1 1 1 0 Septum formation initiator DUF4563 PF15124.1 OAJ25529.1 - 0.15 11.6 0.2 8 5.9 0.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4563) DUF2721 PF11026.3 OAJ25529.1 - 0.49 10.0 1.6 0.81 9.3 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) LSM14 PF12701.2 OAJ25532.1 - 5.9e-28 96.5 0.0 1.2e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 OAJ25532.1 - 1.1e-09 38.7 0.0 1.6e-08 35.0 0.0 2.8 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.1 OAJ25532.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Ataxin 2 SM domain F-box PF00646.28 OAJ25533.1 - 1.5e-05 24.5 0.0 9.5e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 F-box domain Abhydrolase_5 PF12695.2 OAJ25534.1 - 0.0013 18.4 0.0 0.0026 17.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 OAJ25534.1 - 0.093 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) NOGCT PF08155.6 OAJ25537.1 - 1.9e-28 97.9 3.0 4.5e-28 96.7 2.1 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 OAJ25537.1 - 2.6e-28 97.6 0.1 4.5e-28 96.8 0.1 1.4 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 OAJ25537.1 - 5.7e-19 68.1 0.0 1.4e-18 66.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ25537.1 - 1.5e-09 37.3 0.0 2.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 OAJ25537.1 - 4.9e-05 23.8 0.0 0.00013 22.4 0.0 1.8 2 0 0 2 2 1 1 Miro-like protein Dynamin_N PF00350.18 OAJ25537.1 - 0.00075 19.3 0.0 0.63 9.8 0.0 2.8 1 1 1 2 2 2 2 Dynamin family DUF258 PF03193.11 OAJ25537.1 - 0.0029 16.7 0.0 0.044 12.9 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AIG1 PF04548.11 OAJ25537.1 - 0.046 12.8 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family COX16 PF14138.1 OAJ25537.1 - 0.079 13.1 0.1 0.44 10.7 0.1 2.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 SRPRB PF09439.5 OAJ25537.1 - 0.099 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MobB PF03205.9 OAJ25537.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 OAJ25537.1 - 0.12 12.5 0.0 0.95 9.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 OAJ25537.1 - 1.7 9.5 7.6 2.4 9.0 0.0 3.6 3 2 0 3 3 3 0 AAA domain GST_N_3 PF13417.1 OAJ25538.1 - 1.1e-17 64.0 0.0 2.3e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ25538.1 - 5.8e-10 39.0 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAJ25538.1 - 0.00032 20.5 0.5 0.0009 19.0 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 OAJ25538.1 - 0.03 14.4 0.0 0.13 12.4 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain WW PF00397.21 OAJ25539.1 - 1.4e-06 27.9 4.9 3.4e-06 26.8 3.4 1.7 1 0 0 1 1 1 1 WW domain SHOCT PF09851.4 OAJ25540.1 - 0.34 10.4 0.0 0.81 9.2 0.0 1.7 1 0 0 1 1 1 0 Short C-terminal domain Peptidase_M43 PF05572.8 OAJ25541.1 - 3.7e-18 65.5 0.0 5.9e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 OAJ25541.1 - 0.00026 21.4 0.4 0.0014 19.1 0.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 OAJ25541.1 - 0.0022 18.0 1.4 0.0033 17.5 1.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 OAJ25541.1 - 0.0039 16.7 0.4 0.0084 15.6 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAJ25541.1 - 0.031 14.1 2.5 0.054 13.4 1.7 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 OAJ25541.1 - 0.13 11.9 1.5 0.16 11.6 1.0 1.4 1 1 0 1 1 1 0 Matrixin Fringe PF02434.11 OAJ25542.1 - 4.8e-09 35.8 0.4 2.8e-08 33.2 0.3 2.2 1 1 0 1 1 1 1 Fringe-like YjeF_N PF03853.10 OAJ25543.1 - 5.7e-36 123.6 0.0 7.9e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus Acetyltransf_1 PF00583.19 OAJ25544.1 - 6.6e-06 26.0 0.0 1.7e-05 24.7 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ25544.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Dsh_C PF12316.3 OAJ25545.1 - 0.014 15.4 0.7 0.015 15.3 0.5 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Myosin_tail_1 PF01576.14 OAJ25547.1 - 0.0053 14.5 13.7 0.11 10.2 2.8 2.0 1 1 1 2 2 2 2 Myosin tail Leu_zip PF15294.1 OAJ25547.1 - 0.0082 15.2 4.1 0.0082 15.2 2.8 1.4 1 1 0 1 1 1 1 Leucine zipper ATG_C PF09333.6 OAJ25547.1 - 0.021 14.9 3.3 0.2 11.8 0.1 3.2 1 1 2 3 3 3 0 ATG C terminal domain Laminin_II PF06009.7 OAJ25547.1 - 0.025 14.3 10.1 0.82 9.4 0.1 2.6 1 1 1 2 2 2 0 Laminin Domain II Glyco_tran_28_C PF04101.11 OAJ25547.1 - 0.42 10.2 3.4 0.17 11.5 0.7 1.5 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain DUF2968 PF11180.3 OAJ25547.1 - 0.42 9.9 10.2 0.23 10.8 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) APG6 PF04111.7 OAJ25547.1 - 0.52 9.2 6.4 0.68 8.9 4.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Sec2p PF06428.6 OAJ25547.1 - 1.1 9.1 12.3 0.38 10.6 4.5 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p AAA_13 PF13166.1 OAJ25547.1 - 2 6.7 9.0 2.7 6.3 6.2 1.1 1 0 0 1 1 1 0 AAA domain Rootletin PF15035.1 OAJ25547.1 - 2.1 8.2 6.5 7.4 6.5 3.9 1.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion UPRTase PF14681.1 OAJ25549.1 - 6.6e-64 214.9 0.0 7.7e-64 214.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 OAJ25549.1 - 3.3e-08 33.2 0.0 5.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Ras PF00071.17 OAJ25550.1 - 7.6e-58 194.4 0.2 8.8e-58 194.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ25550.1 - 1.9e-18 67.0 0.0 2.7e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ25550.1 - 3.4e-08 32.9 0.0 4.2e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ25550.1 - 3.3e-06 26.6 0.0 6e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ25550.1 - 0.0061 16.5 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ25550.1 - 0.028 13.7 0.1 0.07 12.4 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_25 PF13481.1 OAJ25550.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Transposase_21 PF02992.9 OAJ25551.1 - 5.3e-05 22.4 0.0 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF948 PF06103.6 OAJ25552.1 - 0.23 11.3 4.8 0.11 12.3 0.3 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) L31 PF09784.4 OAJ25552.1 - 2.3 8.3 10.9 9.1 6.4 1.0 3.1 2 1 0 3 3 3 0 Mitochondrial ribosomal protein L31 Sec10 PF07393.6 OAJ25553.1 - 4.3e-238 792.1 0.0 5.5e-238 791.7 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Kri1 PF05178.7 OAJ25553.1 - 0.049 13.8 0.3 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 KRI1-like family MscS_porin PF12795.2 OAJ25553.1 - 0.31 10.3 0.1 0.57 9.4 0.1 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DNA_ligase_A_N PF04675.9 OAJ25554.1 - 2.1e-17 63.4 0.5 3.7e-17 62.7 0.0 1.6 2 0 0 2 2 2 1 DNA ligase N terminus Macoilin PF09726.4 OAJ25554.1 - 0.00018 19.9 11.6 0.00019 19.9 8.0 1.2 1 0 0 1 1 1 1 Transmembrane protein Polysacc_deac_1 PF01522.16 OAJ25555.1 - 2e-22 79.1 0.0 7.5e-22 77.2 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase EHN PF06441.7 OAJ25556.1 - 2e-26 92.0 0.0 3.7e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 OAJ25556.1 - 2.3e-07 30.9 3.7 5.9e-07 29.5 1.2 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ25556.1 - 0.0041 16.7 0.1 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold SRP54 PF00448.17 OAJ25562.1 - 2.9e-75 252.0 0.3 2.9e-75 252.0 0.2 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 OAJ25562.1 - 2.6e-24 85.4 0.7 1.4e-21 76.7 0.0 4.0 2 1 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.14 OAJ25562.1 - 1.2e-11 44.4 1.3 2.5e-11 43.5 0.9 1.5 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 OAJ25562.1 - 1.9e-05 24.5 0.0 5.1e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 OAJ25562.1 - 2e-05 24.0 0.5 0.0001 21.7 0.4 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 OAJ25562.1 - 0.0017 17.8 0.1 0.0049 16.2 0.1 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 OAJ25562.1 - 0.0027 17.6 0.1 1.3 8.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain MobB PF03205.9 OAJ25562.1 - 0.0029 17.3 0.0 0.0063 16.2 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 OAJ25562.1 - 0.0063 16.6 0.0 0.021 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 OAJ25562.1 - 0.012 15.2 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.1 OAJ25562.1 - 0.018 15.8 0.0 0.041 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Lipase_chap PF03280.9 OAJ25562.1 - 0.056 12.9 2.3 1.4 8.4 0.1 2.5 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein AAA_18 PF13238.1 OAJ25562.1 - 0.079 13.2 0.0 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 OAJ25562.1 - 0.12 11.5 0.2 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_25 PF13481.1 OAJ25562.1 - 0.63 9.4 3.1 0.83 9.0 0.2 2.5 2 1 0 2 2 2 0 AAA domain Pet191_N PF10203.4 OAJ25563.1 - 1.1e-23 83.0 1.8 1.2e-23 82.8 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Prefoldin PF02996.12 OAJ25564.1 - 2.1e-26 91.9 0.1 2.5e-26 91.6 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit GAS PF13851.1 OAJ25564.1 - 0.0054 15.9 0.8 0.32 10.1 0.3 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding CCDC155 PF14662.1 OAJ25564.1 - 0.012 15.2 0.7 0.05 13.1 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Prefoldin_2 PF01920.15 OAJ25564.1 - 0.016 14.9 0.2 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit Cep57_MT_bd PF06657.8 OAJ25564.1 - 0.075 12.9 0.3 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Apolipoprotein PF01442.13 OAJ25564.1 - 0.12 11.9 2.4 6 6.3 0.0 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4200 PF13863.1 OAJ25564.1 - 0.27 11.1 1.9 5.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF1192 PF06698.6 OAJ25564.1 - 0.53 10.1 3.1 1.1 9.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) GATA PF00320.22 OAJ25565.1 - 1.1e-26 91.8 21.1 5.7e-14 51.1 3.2 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 OAJ25565.1 - 1.6e-08 33.9 0.2 2.8e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 OAJ25565.1 - 0.0016 17.6 6.3 0.074 12.3 0.9 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding NMD3 PF04981.8 OAJ25565.1 - 0.34 9.9 3.0 2.4 7.1 0.0 2.2 2 0 0 2 2 2 0 NMD3 family DZR PF12773.2 OAJ25565.1 - 0.9 9.4 10.6 2 8.2 0.7 2.8 1 1 2 3 3 3 0 Double zinc ribbon eIF-5_eIF-2B PF01873.12 OAJ25565.1 - 1.4 8.5 7.3 1.7 8.3 0.6 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.7 OAJ25565.1 - 7.8 6.3 9.3 1.1 9.0 0.2 3.1 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Rap_GAP PF02145.10 OAJ25566.1 - 1.1e-47 161.8 0.0 1.7e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP DUF3384 PF11864.3 OAJ25566.1 - 1.6e-39 135.7 0.0 2.4e-38 131.8 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3384) Tuberin PF03542.11 OAJ25566.1 - 5e-26 91.5 5.7 3e-24 85.7 3.3 2.9 2 1 0 2 2 2 1 Tuberin FAD_binding_7 PF03441.9 OAJ25567.1 - 6.4e-63 212.5 0.1 9.1e-63 212.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 OAJ25567.1 - 2.9e-20 72.6 0.0 5.2e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Lysine_decarbox PF03641.9 OAJ25568.1 - 7.3e-34 116.4 0.0 1e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase HMG-CoA_red PF00368.13 OAJ25569.1 - 3.1e-157 523.0 8.2 4.3e-157 522.5 5.7 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 OAJ25569.1 - 3.8e-20 71.8 1.0 1e-09 38.0 0.1 2.6 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 OAJ25569.1 - 9.3e-07 27.1 3.1 0.0012 16.8 0.0 2.2 2 0 0 2 2 2 2 Patched family ubiquitin PF00240.18 OAJ25570.1 - 2e-34 116.8 1.1 2.7e-34 116.3 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 OAJ25570.1 - 8.9e-20 70.1 0.8 1.3e-19 69.6 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.11 OAJ25570.1 - 3.3e-10 39.6 5.0 6e-10 38.8 3.4 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_2 PF14560.1 OAJ25570.1 - 1.2e-05 25.4 0.2 4.1e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAJ25570.1 - 0.00016 21.3 0.7 0.00023 20.9 0.0 1.6 2 0 0 2 2 2 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 OAJ25570.1 - 0.0038 17.0 0.5 0.015 15.1 0.1 2.1 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 OAJ25570.1 - 0.0091 16.1 0.1 0.011 15.9 0.1 1.3 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain HSA PF07529.8 OAJ25571.1 - 3.6e-16 58.7 4.5 3.6e-16 58.7 3.1 4.3 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 OAJ25571.1 - 3.5e-07 30.2 0.0 9.1e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain GMC_oxred_N PF00732.14 OAJ25573.1 - 2.5e-39 135.1 0.0 3.8e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ25573.1 - 1.7e-19 70.5 0.9 3.5e-19 69.5 0.1 2.0 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 OAJ25573.1 - 3.2e-09 36.1 1.8 1.9e-05 23.6 1.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAJ25573.1 - 1.7e-05 23.8 0.2 0.00019 20.4 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ25573.1 - 6.2e-05 22.9 0.4 0.00014 21.7 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 OAJ25573.1 - 0.00013 21.1 0.1 0.0002 20.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAJ25573.1 - 0.0007 19.5 0.1 0.004 17.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ25573.1 - 0.011 14.2 0.5 0.024 13.1 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 OAJ25573.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 OAJ25573.1 - 0.011 14.8 0.4 0.02 14.0 0.3 1.3 1 0 0 1 1 1 0 Thi4 family FliG_M PF14841.1 OAJ25573.1 - 0.015 15.3 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 FliG middle domain FAD_oxidored PF12831.2 OAJ25573.1 - 0.023 13.7 1.2 0.035 13.2 0.8 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 OAJ25573.1 - 0.076 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.11 OAJ25573.1 - 0.16 11.4 0.1 0.28 10.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA eIF-6 PF01912.13 OAJ25574.1 - 4e-81 270.8 0.3 4.7e-81 270.6 0.2 1.0 1 0 0 1 1 1 1 eIF-6 family MULE PF10551.4 OAJ25575.1 - 6.4e-09 35.8 0.0 1.8e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ25575.1 - 0.0035 15.9 0.0 0.0065 15.0 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family TT_ORF2 PF02957.10 OAJ25575.1 - 0.031 14.9 2.1 0.092 13.4 1.5 1.8 1 0 0 1 1 1 0 TT viral ORF2 SDA1 PF05285.7 OAJ25576.1 - 1.3 8.2 17.1 1.7 7.8 2.6 2.3 2 0 0 2 2 2 0 SDA1 Myb_DNA-bind_4 PF13837.1 OAJ25577.1 - 3.5e-05 23.8 0.2 6.5e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain FAD_binding_6 PF00970.19 OAJ25578.1 - 1.3e-06 28.4 0.0 8.4e-06 25.8 0.0 2.3 3 0 0 3 3 3 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 OAJ25578.1 - 0.0016 18.9 0.0 0.84 10.2 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Ank_2 PF12796.2 OAJ25581.1 - 1.1e-07 32.0 1.1 0.00079 19.7 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ25581.1 - 9.6e-06 25.1 0.1 0.023 14.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 OAJ25581.1 - 1.4e-05 25.4 0.1 0.00012 22.4 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ25581.1 - 0.0038 17.3 0.0 0.18 12.1 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Glycogen_syn PF05693.8 OAJ25582.1 - 0 1116.3 0.0 0 1116.0 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 OAJ25582.1 - 8.9e-09 34.9 0.0 7.4e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 OAJ25582.1 - 6.6e-07 29.0 0.1 1.7e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 OAJ25582.1 - 1.3e-05 25.4 0.0 2.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Caleosin PF05042.8 OAJ25583.1 - 1.3e-49 168.0 0.0 1.8e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein FA_desaturase PF00487.19 OAJ25589.1 - 7.3e-26 91.1 17.5 1.3e-25 90.3 12.2 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 OAJ25589.1 - 1.5e-16 59.3 0.2 2.6e-16 58.5 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) MULE PF10551.4 OAJ25590.1 - 8e-10 38.7 0.0 1.6e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ25590.1 - 4.8e-05 22.0 0.0 8.3e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family RVT_2 PF07727.9 OAJ25591.1 - 9.5e-86 286.7 0.0 1.3e-85 286.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ25591.1 - 3.9e-20 72.1 0.0 1.5e-19 70.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ25591.1 - 1.8e-05 24.2 0.2 4.1e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 OAJ25592.1 - 4.1e-07 29.7 0.0 7.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAJ25592.1 - 1.5e-05 24.4 0.0 3.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1400 PF07176.6 OAJ25592.1 - 0.015 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) zf-CCHC PF00098.18 OAJ25592.1 - 0.016 15.0 3.9 0.016 15.0 2.7 1.8 2 0 0 2 2 2 0 Zinc knuckle 4HBT_3 PF13622.1 OAJ25593.1 - 5.1e-29 101.7 2.9 6.7e-29 101.3 2.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily MBOAT PF03062.14 OAJ25594.1 - 3.4e-31 108.5 15.6 3.4e-31 108.5 10.8 3.0 2 2 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family WD40 PF00400.27 OAJ25597.1 - 6.4e-13 48.0 1.9 0.7 9.8 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Yae1_N PF09811.4 OAJ25599.1 - 0.19 11.2 0.3 0.19 11.2 0.2 2.5 2 1 0 2 2 2 0 Essential protein Yae1, N terminal DUF3827 PF12877.2 OAJ25599.1 - 0.7 7.9 7.7 0.87 7.6 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF3807 PF12720.2 OAJ25599.1 - 9.4 6.3 12.1 15 5.6 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Orn_Arg_deC_N PF02784.11 OAJ25600.1 - 2.6e-69 233.2 0.0 3.6e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 OAJ25600.1 - 6.8e-29 99.9 0.0 1.3e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain B12-binding PF02310.14 OAJ25600.1 - 0.04 13.7 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain zf-C2H2_jaz PF12171.3 OAJ25601.1 - 2.2e-09 37.1 2.2 3.8e-09 36.4 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAJ25601.1 - 6.5e-06 26.1 1.3 1e-05 25.5 0.9 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 OAJ25601.1 - 0.00082 19.4 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Bot1p PF12298.3 OAJ25601.1 - 0.034 14.1 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein AKAP95 PF04988.7 OAJ25601.1 - 0.058 13.1 1.0 0.068 12.9 0.1 1.5 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.21 OAJ25601.1 - 0.12 12.7 2.3 0.12 12.7 1.6 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Catalase PF00199.14 OAJ25602.1 - 1.5e-177 590.0 1.2 1.8e-177 589.8 0.8 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 OAJ25602.1 - 3.1e-20 71.8 0.0 7.1e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive PTR2 PF00854.16 OAJ25603.1 - 4.3e-40 137.6 14.8 3.6e-23 81.9 4.7 2.3 2 0 0 2 2 2 2 POT family MFS_1 PF07690.11 OAJ25604.1 - 4.2e-22 78.3 20.1 5.7e-22 77.9 14.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ25604.1 - 2.5e-06 26.3 10.9 3.3e-06 25.9 7.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter HLH PF00010.21 OAJ25605.1 - 1.5e-07 31.0 0.3 2.6e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nucleoplasmin PF03066.10 OAJ25605.1 - 0.0061 16.0 3.3 0.0093 15.4 2.3 1.3 1 0 0 1 1 1 1 Nucleoplasmin Daxx PF03344.10 OAJ25605.1 - 0.035 12.6 7.2 0.082 11.3 5.0 1.6 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 OAJ25605.1 - 0.063 12.3 8.4 0.11 11.5 5.8 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 OAJ25605.1 - 0.074 10.9 7.4 0.14 10.0 5.1 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 OAJ25605.1 - 0.12 10.4 2.8 0.21 9.5 1.9 1.5 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 OAJ25605.1 - 0.25 10.2 1.7 0.39 9.6 1.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.4 OAJ25605.1 - 1 8.0 17.1 8.1 5.0 11.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 OAJ25605.1 - 1.1 9.6 11.9 3.8 7.8 8.3 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L38e PF01781.13 OAJ25606.1 - 2e-31 107.5 0.4 2.5e-31 107.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF2344 PF10105.4 OAJ25606.1 - 0.072 12.5 0.2 0.29 10.5 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) IBN_N PF03810.14 OAJ25607.1 - 4.9e-06 26.3 0.0 3.9e-05 23.4 0.0 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain polyprenyl_synt PF00348.12 OAJ25608.1 - 6.1e-40 136.6 0.0 4.3e-19 68.3 0.0 4.1 4 0 0 4 4 4 4 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 OAJ25608.1 - 0.026 13.9 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Clat_adaptor_s PF01217.15 OAJ25609.1 - 1.1e-54 184.0 0.2 1.3e-54 183.8 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PAXNEB PF05625.6 OAJ25611.1 - 1.1e-28 100.1 0.0 1e-17 64.0 0.0 3.9 4 0 0 4 4 4 3 PAXNEB protein PPR_1 PF12854.2 OAJ25613.1 - 0.005 16.2 0.0 0.0089 15.4 0.0 1.4 1 0 0 1 1 1 1 PPR repeat PPR PF01535.15 OAJ25613.1 - 0.012 15.5 0.0 0.076 13.0 0.0 2.1 2 0 0 2 2 2 0 PPR repeat PPR_2 PF13041.1 OAJ25613.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 PPR repeat family Ribosomal_S11 PF00411.14 OAJ25614.1 - 2.4e-37 127.4 0.4 3.5e-37 126.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 MBOAT PF03062.14 OAJ25615.1 - 5.2e-49 167.1 21.6 5.2e-49 167.1 14.9 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family AdoHcyase PF05221.12 OAJ25616.1 - 4.4e-139 461.9 0.0 5e-139 461.7 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 OAJ25616.1 - 1.7e-83 278.3 2.1 2.5e-83 277.7 1.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 OAJ25616.1 - 6.3e-09 35.2 0.1 1.4e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 OAJ25616.1 - 0.00057 19.2 0.1 0.00095 18.5 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 OAJ25616.1 - 0.0029 17.5 0.1 0.0067 16.4 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain DUF4448 PF14610.1 OAJ25616.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) NAD_binding_7 PF13241.1 OAJ25616.1 - 0.077 13.2 0.2 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding IBN_N PF03810.14 OAJ25622.1 - 1.6e-14 53.5 0.0 7.4e-12 45.0 0.0 3.1 3 0 0 3 3 3 2 Importin-beta N-terminal domain Cse1 PF08506.5 OAJ25622.1 - 3.8e-08 32.2 0.0 1.1e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.7 OAJ25622.1 - 1.5e-05 24.9 1.3 0.00053 19.9 0.0 3.0 2 1 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.1 OAJ25622.1 - 0.0066 16.7 8.2 0.17 12.2 0.0 4.1 5 0 0 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.2 OAJ25622.1 - 0.019 15.3 0.1 0.7 10.3 0.0 3.7 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region HTH_psq PF05225.11 OAJ25622.1 - 0.055 13.0 0.2 0.15 11.6 0.1 1.8 1 0 0 1 1 1 0 helix-turn-helix, Psq domain AAA PF00004.24 OAJ25623.1 - 1e-96 320.1 0.0 2.1e-47 160.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 OAJ25623.1 - 1.6e-22 79.2 0.1 7e-22 77.1 0.0 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 OAJ25623.1 - 8.6e-16 57.6 0.0 2e-05 23.7 0.0 4.0 4 1 0 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 OAJ25623.1 - 2.4e-13 50.1 0.0 1.6e-06 28.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.9 OAJ25623.1 - 4.6e-13 49.4 0.0 3.6e-07 30.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 OAJ25623.1 - 2.5e-12 46.7 0.4 6.1e-06 25.9 0.0 3.9 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 OAJ25623.1 - 1.6e-11 45.0 0.0 0.00054 20.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAJ25623.1 - 3.9e-11 43.2 0.2 0.0016 18.5 0.0 4.0 2 2 1 3 3 2 2 AAA domain CDC48_2 PF02933.12 OAJ25623.1 - 3.6e-10 39.3 0.0 7.7e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.8 OAJ25623.1 - 2.3e-09 36.4 0.0 0.0013 17.4 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 OAJ25623.1 - 4.9e-09 36.4 0.0 0.0065 16.4 0.0 3.3 2 2 0 2 2 2 2 AAA ATPase domain Vps4_C PF09336.5 OAJ25623.1 - 1e-08 34.9 0.1 5.3e-08 32.6 0.0 2.2 2 1 1 3 3 1 1 Vps4 C terminal oligomerisation domain Zeta_toxin PF06414.7 OAJ25623.1 - 1e-08 34.5 0.0 0.005 15.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 OAJ25623.1 - 3.6e-08 33.0 0.0 0.0032 16.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 OAJ25623.1 - 3.8e-08 32.7 0.4 0.0022 17.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 OAJ25623.1 - 4.3e-08 32.7 3.1 0.0031 16.9 0.0 4.0 3 2 1 5 5 4 2 AAA domain AAA_14 PF13173.1 OAJ25623.1 - 6.1e-08 32.6 0.0 0.0064 16.3 0.0 3.2 4 0 0 4 4 2 2 AAA domain AAA_19 PF13245.1 OAJ25623.1 - 3.4e-07 29.9 1.7 0.015 15.0 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain RNA_helicase PF00910.17 OAJ25623.1 - 1.2e-06 28.5 0.0 0.014 15.5 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 OAJ25623.1 - 3.1e-06 27.2 0.0 0.058 13.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 OAJ25623.1 - 4e-06 27.1 0.0 0.042 14.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 OAJ25623.1 - 4.9e-06 25.8 1.0 0.86 8.6 0.0 3.5 2 1 1 3 3 3 2 KaiC Parvo_NS1 PF01057.12 OAJ25623.1 - 5.2e-06 25.5 0.2 0.0053 15.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 OAJ25623.1 - 7.3e-06 25.9 0.0 0.0079 16.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF815 PF05673.8 OAJ25623.1 - 7.5e-06 25.0 0.0 0.0021 17.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 OAJ25623.1 - 1.6e-05 24.6 0.1 0.067 12.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.22 OAJ25623.1 - 1.6e-05 25.2 0.0 0.11 12.7 0.0 3.6 3 1 0 3 3 2 1 ABC transporter Sigma54_activat PF00158.21 OAJ25623.1 - 1.7e-05 24.3 0.0 0.36 10.2 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 OAJ25623.1 - 2.4e-05 24.4 0.0 0.17 11.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 OAJ25623.1 - 4.9e-05 22.6 0.2 0.31 10.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.7 OAJ25623.1 - 5.1e-05 22.9 0.1 0.07 12.7 0.0 3.4 3 0 0 3 3 3 1 NACHT domain Arch_ATPase PF01637.13 OAJ25623.1 - 0.00012 21.8 0.5 2.1 7.9 0.0 3.6 3 1 1 4 4 3 1 Archaeal ATPase AAA_3 PF07726.6 OAJ25623.1 - 0.00014 21.4 0.0 0.42 10.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 OAJ25623.1 - 0.00016 21.3 0.0 0.57 9.7 0.0 2.7 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_11 PF13086.1 OAJ25623.1 - 0.00043 19.9 0.0 0.81 9.2 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 OAJ25623.1 - 0.0006 19.4 0.0 0.91 9.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 OAJ25623.1 - 0.00078 19.0 0.0 0.13 11.7 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 OAJ25623.1 - 0.002 17.6 1.1 1.2 8.5 0.0 3.9 3 1 1 4 4 4 1 AAA-like domain NB-ARC PF00931.17 OAJ25623.1 - 0.0025 16.7 0.1 0.24 10.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 OAJ25623.1 - 0.0027 17.4 0.2 0.75 9.4 0.0 3.5 3 0 0 3 3 3 1 NTPase DUF2075 PF09848.4 OAJ25623.1 - 0.0028 16.6 0.8 0.9 8.4 0.0 2.6 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 OAJ25623.1 - 0.0078 15.1 0.0 0.23 10.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein IPT PF01745.11 OAJ25623.1 - 0.021 13.9 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Molydop_binding PF01568.16 OAJ25623.1 - 0.022 14.5 0.3 0.86 9.4 0.0 3.1 2 1 1 3 3 3 0 Molydopterin dinucleotide binding domain UPF0079 PF02367.12 OAJ25623.1 - 0.026 14.1 0.1 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 OAJ25623.1 - 0.038 13.2 0.0 4.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 KAP_NTPase PF07693.9 OAJ25623.1 - 0.039 12.9 0.0 0.75 8.7 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain ATP-synt_ab PF00006.20 OAJ25623.1 - 0.048 13.1 0.1 3.7 7.0 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DNA_ligase_A_C PF04679.10 OAJ25623.1 - 0.054 13.9 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region AFG1_ATPase PF03969.11 OAJ25623.1 - 0.074 11.8 0.0 7.7 5.2 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase MobB PF03205.9 OAJ25623.1 - 0.093 12.4 0.4 5.3 6.7 0.0 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 OAJ25623.1 - 0.1 12.8 0.0 1 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 OAJ25623.1 - 0.1 12.4 0.8 6.9 6.5 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase UFD1 PF03152.9 OAJ25623.1 - 0.14 11.2 0.0 0.33 10.0 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Ribosomal_L2_C PF03947.13 OAJ25624.1 - 6.3e-42 142.4 1.1 8.8e-42 141.9 0.8 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 OAJ25624.1 - 0.099 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal Proteins L2, RNA binding domain UPRTase PF14681.1 OAJ25625.1 - 7.3e-79 263.7 0.0 8.4e-79 263.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 OAJ25625.1 - 0.00024 20.8 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain peroxidase PF00141.18 OAJ25626.1 - 2.2e-51 174.5 0.0 3e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Transposase_21 PF02992.9 OAJ25627.1 - 1.8e-10 40.2 0.0 3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ25627.1 - 0.00062 19.2 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Pyrophosphatase PF00719.14 OAJ25629.1 - 9.2e-54 181.1 0.2 1.2e-53 180.7 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Lactamase_B_3 PF13483.1 OAJ25630.1 - 0.13 11.9 0.1 0.31 10.7 0.1 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain ChaC PF04752.7 OAJ25631.1 - 1.7e-50 171.4 0.0 4.1e-50 170.2 0.0 1.7 1 0 0 1 1 1 1 ChaC-like protein DnaJ PF00226.26 OAJ25631.1 - 1.2e-26 92.1 0.7 3.9e-26 90.5 0.5 2.0 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 OAJ25631.1 - 2.6e-09 36.9 1.0 5.9e-09 35.8 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAJ25631.1 - 5e-06 26.5 0.5 9.2e-06 25.6 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 OAJ25631.1 - 0.011 15.8 0.1 0.035 14.2 0.1 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) APOBEC_C PF05240.9 OAJ25631.1 - 0.084 12.2 0.3 0.18 11.2 0.2 1.5 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Tub_2 PF04525.7 OAJ25632.1 - 2e-28 99.0 0.0 2.4e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 DUF2360 PF10152.4 OAJ25633.1 - 0.0084 16.4 0.2 0.048 13.9 0.1 2.2 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Sugarporin_N PF11471.3 OAJ25633.1 - 0.046 13.3 0.3 0.096 12.3 0.2 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension HSP70 PF00012.15 OAJ25634.1 - 1.3e-06 26.6 0.0 1.5e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Toxin_58 PF15536.1 OAJ25635.1 - 0.13 12.1 1.3 0.17 11.7 0.9 1.1 1 0 0 1 1 1 0 Putative toxin 58 PH_10 PF15411.1 OAJ25636.1 - 1.3e-21 76.9 0.0 2.8e-21 75.8 0.0 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 OAJ25636.1 - 9.9e-05 22.0 0.0 0.014 15.0 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain PH PF00169.24 OAJ25636.1 - 0.072 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 PH domain Pkinase PF00069.20 OAJ25638.1 - 6e-38 130.4 0.0 1.3e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ25638.1 - 1.8e-10 40.3 0.0 2.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinetochor_Ybp2 PF08568.5 OAJ25638.1 - 4.3e-09 35.2 0.0 3.1e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin APH PF01636.18 OAJ25638.1 - 2e-05 24.4 0.0 9.6e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAJ25638.1 - 0.0014 18.2 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Paramyx_P_V_C PF03210.8 OAJ25639.1 - 0.0012 18.6 1.7 0.0018 18.1 1.0 1.4 1 1 0 1 1 1 1 Paramyxovirus P/V phosphoprotein C-terminal Cytochrom_C1 PF02167.10 OAJ25639.1 - 0.016 14.8 0.1 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 Cytochrome C1 family Cluap1 PF10234.4 OAJ25639.1 - 0.022 13.9 4.6 0.026 13.7 3.2 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 End3 PF12761.2 OAJ25639.1 - 0.051 13.2 1.9 0.055 13.1 1.3 1.0 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Laminin_II PF06009.7 OAJ25639.1 - 0.052 13.3 4.2 0.091 12.5 2.9 1.4 1 1 0 1 1 1 0 Laminin Domain II Eapp_C PF10238.4 OAJ25639.1 - 0.064 13.1 0.6 0.068 13.0 0.4 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein PFL PF02901.10 OAJ25639.1 - 0.073 11.4 7.5 0.089 11.2 5.2 1.0 1 0 0 1 1 1 0 Pyruvate formate lyase HAUS6_N PF14661.1 OAJ25639.1 - 0.076 12.3 5.7 0.083 12.2 3.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TarH PF02203.10 OAJ25639.1 - 0.22 11.3 4.9 0.27 11.0 3.4 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue UPF0122 PF04297.9 OAJ25639.1 - 0.23 11.5 3.7 0.3 11.1 2.4 1.3 1 1 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like MAP7 PF05672.6 OAJ25639.1 - 0.31 10.3 7.8 0.4 10.0 5.4 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Cache_3 PF14827.1 OAJ25639.1 - 0.51 10.2 2.4 0.84 9.5 1.7 1.5 1 1 0 1 1 1 0 Sensory domain of two-component sensor kinase APG6 PF04111.7 OAJ25639.1 - 2.3 7.1 7.4 2.7 6.9 5.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 OAJ25639.1 - 5.7 6.4 8.1 8.2 5.9 2.9 2.2 1 1 1 2 2 2 0 Septum formation initiator DHO_dh PF01180.16 OAJ25641.1 - 2.2e-90 302.5 0.0 3.2e-90 302.0 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 OAJ25641.1 - 0.00043 19.2 0.0 0.0088 14.9 0.0 3.0 3 1 0 3 3 3 1 FMN-dependent dehydrogenase NMO PF03060.10 OAJ25641.1 - 0.00087 18.5 0.0 0.0023 17.1 0.0 1.7 1 0 0 1 1 1 1 Nitronate monooxygenase FA_hydroxylase PF04116.8 OAJ25642.1 - 4e-14 53.0 26.0 1.4e-13 51.2 15.6 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_60s PF00428.14 OAJ25642.1 - 0.07 13.5 8.7 0.14 12.6 6.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Scs3p PF10261.4 OAJ25643.1 - 3.7e-48 163.6 0.0 6.1e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM YsaB PF13983.1 OAJ25643.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 YsaB-like lipoprotein DUF938 PF06080.7 OAJ25644.1 - 3.6e-29 101.7 0.0 5e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_18 PF12847.2 OAJ25644.1 - 0.0015 19.0 0.1 0.0037 17.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ25644.1 - 0.004 16.8 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ25644.1 - 0.021 15.2 0.1 0.09 13.2 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ25644.1 - 0.14 12.5 0.1 0.95 9.8 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Med11 PF10280.4 OAJ25645.1 - 8.8e-06 25.7 0.0 1.6e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Mediator complex protein RRM_1 PF00076.17 OAJ25646.1 - 3.7e-34 116.1 0.0 8.3e-17 60.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ25646.1 - 2.2e-26 91.5 0.0 6.7e-12 45.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ25646.1 - 9.5e-11 41.3 0.0 0.00029 20.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDK2AP PF09806.4 OAJ25646.1 - 0.00029 21.1 3.0 0.00029 21.1 2.1 3.5 2 1 0 2 2 2 1 Cyclin-dependent kinase 2-associated protein RRM_3 PF08777.6 OAJ25646.1 - 0.14 12.0 0.3 22 4.9 0.0 3.3 3 0 0 3 3 3 0 RNA binding motif DUF221 PF02714.10 OAJ25647.1 - 2e-39 135.3 16.0 2.9e-39 134.8 11.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAJ25647.1 - 1.9e-15 56.7 2.6 1.9e-15 56.7 1.8 3.8 4 1 1 5 5 5 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 OAJ25647.1 - 0.00085 19.7 0.8 0.06 13.8 0.0 3.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 OAJ25647.1 - 0.0048 16.8 0.0 3.3 7.7 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Katanin_con80 PF13925.1 OAJ25647.1 - 0.12 12.1 0.6 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 con80 domain of Katanin MULE PF10551.4 OAJ25648.1 - 3.7e-12 46.2 0.1 1.4e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 OAJ25648.1 - 2.1e-08 33.1 2.5 1e-07 30.9 0.1 2.2 2 0 0 2 2 2 1 Transposase, Mutator family FAR1 PF03101.10 OAJ25648.1 - 0.014 15.9 1.2 0.029 14.8 0.8 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Zip PF02535.17 OAJ25649.1 - 0.018 14.0 1.2 0.024 13.6 0.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 OAJ25649.1 - 6.5 6.0 15.4 11 5.2 10.6 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pinin_SDK_memA PF04696.8 OAJ25650.1 - 8.1e-08 31.9 5.0 8.1e-08 31.9 3.5 3.1 3 0 0 3 3 3 2 pinin/SDK/memA/ protein conserved region Mei4 PF13971.1 OAJ25650.1 - 0.056 12.3 0.6 0.15 11.0 0.1 1.7 2 0 0 2 2 2 0 Meiosis-specific protein Mei4 DUF2884 PF11101.3 OAJ25650.1 - 0.68 9.2 7.5 1.8 7.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Ecl1 PF12855.2 OAJ25654.1 - 7e-08 31.6 0.0 0.0032 16.7 0.0 2.5 2 0 0 2 2 2 2 Life-span regulatory factor GMC_oxred_N PF00732.14 OAJ25655.1 - 3.8e-51 174.0 0.0 6.3e-51 173.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ25655.1 - 1.9e-36 125.4 0.0 4.2e-36 124.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAJ25655.1 - 0.00013 21.0 0.2 0.0012 17.8 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ25655.1 - 0.0014 18.6 0.2 0.006 16.5 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAJ25655.1 - 0.0022 16.8 1.0 0.1 11.4 0.8 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 OAJ25655.1 - 0.0025 16.8 0.7 0.0045 15.9 0.5 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 OAJ25655.1 - 0.0037 17.1 1.2 0.018 14.9 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_16 PF00722.16 OAJ25656.1 - 1.8e-30 105.6 1.2 4.6e-30 104.2 0.8 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MutL_C PF08676.6 OAJ25656.1 - 2.4e-08 33.7 0.0 4.8e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 OAJ25656.1 - 0.0024 17.5 0.0 0.0066 16.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAJ25656.1 - 0.005 16.4 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2985 PF11204.3 OAJ25657.1 - 1.6e-27 95.0 3.6 3e-27 94.1 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Sensor PF13796.1 OAJ25657.1 - 0.0065 16.0 0.1 0.024 14.2 0.1 2.0 1 0 0 1 1 1 1 Putative sensor Pyr_redox_3 PF13738.1 OAJ25658.1 - 4.3e-13 49.7 0.0 6.7e-12 45.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ25658.1 - 4.1e-09 36.3 0.2 0.0003 20.5 0.0 3.5 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAJ25658.1 - 5.7e-09 35.8 0.0 2.2e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 OAJ25658.1 - 2.9e-06 25.7 0.0 0.13 10.4 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 OAJ25658.1 - 2.9e-05 24.0 0.0 0.091 12.6 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ25658.1 - 4.7e-05 22.4 0.0 0.0092 14.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 OAJ25658.1 - 9.2e-05 21.4 0.4 0.022 13.7 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 OAJ25658.1 - 0.012 15.6 0.0 6.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 OAJ25658.1 - 0.017 14.2 0.0 0.055 12.5 0.0 1.8 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 OAJ25658.1 - 0.033 12.6 0.0 1.5 7.1 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 OAJ25658.1 - 0.037 12.9 0.1 2.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 OAJ25658.1 - 0.049 12.5 0.0 5.6 5.7 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 OAJ25658.1 - 0.19 12.1 0.1 0.42 11.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CRAL_TRIO PF00650.15 OAJ25660.1 - 3.7e-34 117.5 0.0 5.7e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ25660.1 - 1.1e-08 35.0 0.4 3.1e-08 33.6 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain ThiS PF02597.15 OAJ25660.1 - 5.3e-08 33.1 0.1 4.7e-07 30.1 0.1 2.5 2 0 0 2 2 2 1 ThiS family Fe_bilin_red PF05996.7 OAJ25660.1 - 1.5 8.2 6.0 2.7 7.4 4.1 1.3 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase Aa_trans PF01490.13 OAJ25661.1 - 1.2e-45 155.7 32.5 1.4e-45 155.5 22.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sex_peptide PF08138.6 OAJ25661.1 - 0.072 12.9 0.0 14 5.6 0.0 3.7 3 0 0 3 3 3 0 Sex peptide (SP) family DUF4231 PF14015.1 OAJ25661.1 - 0.52 10.3 0.0 0.52 10.3 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Anoctamin PF04547.7 OAJ25661.1 - 3.1 6.3 10.7 0.015 14.0 0.7 2.1 2 1 0 2 2 2 0 Calcium-activated chloride channel Allantoicase PF03561.10 OAJ25662.1 - 8.5e-84 278.5 0.0 7.4e-42 142.3 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_hydro PF04115.7 OAJ25662.1 - 2.5e-46 157.0 0.0 3.8e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate hydrolase G6PD_C PF02781.11 OAJ25663.1 - 1.6e-121 404.7 0.0 2e-121 404.3 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 OAJ25663.1 - 7.7e-63 212.0 0.1 1.6e-62 210.9 0.1 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Tub_2 PF04525.7 OAJ25664.1 - 8.5e-19 67.6 0.0 1e-18 67.4 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 Uds1 PF15456.1 OAJ25666.1 - 2.6e-14 53.3 3.8 1.7e-11 44.2 0.2 14.6 6 1 7 14 14 14 2 Up-regulated During Septation Methyltransf_28 PF02636.12 OAJ25667.1 - 3.1e-64 216.8 0.0 3.8e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.20 OAJ25668.1 - 1.4e-71 240.7 0.0 1.7e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ25668.1 - 5.4e-31 107.6 0.0 7e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 OAJ25668.1 - 3.8e-13 49.7 0.9 1.2e-12 48.0 0.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 OAJ25668.1 - 1.7e-05 23.9 0.0 4.8e-05 22.4 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 OAJ25668.1 - 0.0081 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ25668.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4028 PF13220.1 OAJ25669.1 - 0.0018 17.8 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4028) SGS PF05002.10 OAJ25670.1 - 9.6e-26 89.3 1.7 2e-25 88.3 1.1 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.11 OAJ25670.1 - 1.9e-08 34.7 0.0 5.4e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 CS domain DUF2348 PF09807.4 OAJ25671.1 - 0.00021 20.5 0.0 0.00035 19.7 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) AAA_25 PF13481.1 OAJ25671.1 - 0.00061 19.2 0.1 0.00099 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 OAJ25671.1 - 0.015 14.9 0.0 0.034 13.8 0.0 1.5 1 1 0 1 1 1 0 NACHT domain Aminotran_5 PF00266.14 OAJ25672.1 - 3.1e-30 105.1 0.0 4e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MFS_1 PF07690.11 OAJ25672.1 - 2.9e-27 95.3 49.2 8.3e-27 93.8 33.4 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily ABC2_membrane PF01061.19 OAJ25673.1 - 1.5e-13 50.4 13.7 7.1e-09 35.1 0.3 2.4 1 1 1 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 OAJ25673.1 - 5e-12 46.2 0.0 8.6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 OAJ25673.1 - 0.0021 18.0 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 OAJ25673.1 - 0.0041 16.2 0.0 0.0059 15.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain HCO3_cotransp PF00955.16 OAJ25678.1 - 5.4e-40 137.5 16.5 8e-22 77.5 4.1 3.1 2 1 1 3 3 3 3 HCO3- transporter family IU_nuc_hydro PF01156.14 OAJ25679.1 - 8.6e-93 310.9 0.0 1e-92 310.7 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Transposase_21 PF02992.9 OAJ25680.1 - 3.8e-14 52.3 0.0 2.8e-13 49.5 0.0 2.0 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ25680.1 - 0.00015 21.1 0.0 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF3701 PF12482.3 OAJ25681.1 - 0.026 14.2 0.5 0.2 11.3 0.0 2.6 2 1 1 3 3 3 0 Phage integrase protein p450 PF00067.17 OAJ25682.1 - 1.9e-44 152.0 0.0 3e-44 151.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 RHH_4 PF13467.1 OAJ25682.1 - 0.1 12.5 0.7 1.4 8.8 0.6 2.6 3 0 0 3 3 3 0 Ribbon-helix-helix domain Rifin_STEVOR PF02009.11 OAJ25682.1 - 0.36 10.4 4.2 0.67 9.5 2.9 1.4 1 0 0 1 1 1 0 Rifin/stevor family VHS PF00790.14 OAJ25683.1 - 5.7e-41 139.4 0.0 1.6e-40 138.0 0.0 1.7 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 OAJ25683.1 - 2.5e-20 72.3 0.0 6.2e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 GAT domain Spc97_Spc98 PF04130.8 OAJ25684.1 - 1.8e-108 363.2 0.0 2.9e-108 362.5 0.0 1.4 1 1 0 1 1 1 1 Spc97 / Spc98 family Nop53 PF07767.6 OAJ25684.1 - 0.0036 16.3 9.8 0.0036 16.3 6.8 1.8 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) DUF4484 PF14831.1 OAJ25684.1 - 0.0099 15.9 6.2 1.8 8.6 2.6 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4484) Apt1 PF10351.4 OAJ25684.1 - 0.12 11.2 3.6 0.25 10.1 2.5 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.9 OAJ25684.1 - 1.4 6.8 19.4 2.4 6.0 13.4 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 OAJ25684.1 - 1.6 8.3 21.3 5.1 6.6 14.8 1.8 1 0 0 1 1 1 0 YL1 nuclear protein HSP90 PF00183.13 OAJ25684.1 - 4.3 5.6 10.0 8 4.7 6.9 1.3 1 0 0 1 1 1 0 Hsp90 protein Nucleoporin_FG PF13634.1 OAJ25685.1 - 0.0015 18.7 28.8 0.0015 18.7 20.0 3.4 2 1 1 3 3 3 2 Nucleoporin FG repeat region RR_TM4-6 PF06459.7 OAJ25685.1 - 6.8 6.5 15.0 13 5.6 10.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DcpS_C PF11969.3 OAJ25687.1 - 7.1e-21 74.5 0.7 1.2e-20 73.9 0.5 1.3 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 OAJ25687.1 - 1.3e-08 35.2 3.6 5.5e-08 33.2 2.5 1.8 1 1 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.10 OAJ25687.1 - 0.008 15.8 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 AATF-Che1 PF13339.1 OAJ25688.1 - 0.0082 16.2 0.9 0.0082 16.2 0.6 2.6 4 0 0 4 4 4 1 Apoptosis antagonizing transcription factor Chorion_3 PF05387.6 OAJ25688.1 - 0.29 10.5 2.5 0.44 9.9 1.7 1.2 1 0 0 1 1 1 0 Chorion family 3 DUF1129 PF06570.6 OAJ25688.1 - 1.1 8.5 2.5 1.8 7.8 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Gly-rich_Ago1 PF12764.2 OAJ25688.1 - 3 8.5 7.8 8.7 7.0 5.4 1.8 1 0 0 1 1 1 0 Glycine-rich region of argonaut WD40 PF00400.27 OAJ25689.1 - 4.9e-29 99.1 1.2 4.2e-08 32.7 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 OAJ25689.1 - 7.6e-05 22.5 0.0 0.014 15.1 0.0 2.4 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A HycA_repressor PF11046.3 OAJ25690.1 - 0.093 12.6 0.1 0.11 12.4 0.1 1.0 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons Frag1 PF10277.4 OAJ25691.1 - 1.2e-36 126.1 14.5 1.4e-36 125.9 10.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Yip1 PF04893.12 OAJ25691.1 - 0.0041 16.6 4.4 0.0041 16.6 3.1 2.5 1 1 1 2 2 2 1 Yip1 domain Tic20 PF09685.5 OAJ25691.1 - 0.051 13.5 12.2 0.41 10.6 2.7 2.8 1 1 1 2 2 2 0 Tic20-like protein Virul_fac_BrkB PF03631.10 OAJ25691.1 - 0.067 12.5 9.4 0.11 11.8 6.1 1.8 1 1 1 2 2 2 0 Virulence factor BrkB DUF1980 PF09323.5 OAJ25691.1 - 0.19 11.4 7.4 0.074 12.7 2.7 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) E1-E2_ATPase PF00122.15 OAJ25691.1 - 2.9 6.8 6.2 5.1 6.0 3.7 1.7 1 1 0 1 1 1 0 E1-E2 ATPase MgtE PF01769.11 OAJ25691.1 - 8.1 6.7 12.9 12 6.1 0.2 2.8 1 1 2 3 3 3 0 Divalent cation transporter Peptidase_M43 PF05572.8 OAJ25693.1 - 2.9e-17 62.6 0.1 4.5e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.1 OAJ25693.1 - 0.00013 21.5 0.1 0.00018 21.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 OAJ25693.1 - 0.00067 20.1 0.2 0.002 18.6 0.1 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 OAJ25693.1 - 0.00084 19.0 0.0 0.0015 18.2 0.0 1.4 1 1 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.1 OAJ25693.1 - 0.0049 16.9 0.5 0.0095 16.0 0.2 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAJ25693.1 - 0.0054 16.6 0.1 0.01 15.8 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M7 PF02031.11 OAJ25693.1 - 0.034 13.8 0.1 0.068 12.8 0.1 1.5 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family CCAP PF11105.3 OAJ25695.1 - 0.7 9.6 3.6 2 8.1 0.3 2.1 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a zf-CCCH_2 PF14608.1 OAJ25695.1 - 1.2 9.2 14.4 0.87 9.6 0.6 3.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type PINIT PF14324.1 OAJ25696.1 - 2.8e-22 79.3 0.3 4.3e-22 78.7 0.2 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 OAJ25696.1 - 2.2e-20 71.9 4.3 3.5e-20 71.2 3.0 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 OAJ25696.1 - 1.4e-07 30.8 1.0 2.8e-07 29.9 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 OAJ25696.1 - 0.084 12.4 1.2 0.12 11.8 0.1 1.9 2 0 0 2 2 2 0 SAP domain rRNA_proc-arch PF13234.1 OAJ25698.1 - 1.8e-78 263.3 0.1 2.9e-78 262.7 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 OAJ25698.1 - 1.1e-56 190.9 1.1 2.6e-56 189.7 0.7 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 OAJ25698.1 - 1.3e-21 76.7 0.0 4.1e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ25698.1 - 4e-06 26.5 0.0 1.2e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DivIC PF04977.10 OAJ25701.1 - 0.025 14.0 1.8 0.025 14.0 1.2 1.9 2 0 0 2 2 2 0 Septum formation initiator Prefoldin PF02996.12 OAJ25701.1 - 0.029 13.9 2.8 0.043 13.4 0.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF812 PF05667.6 OAJ25701.1 - 0.098 11.1 3.5 0.13 10.7 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) AAA_13 PF13166.1 OAJ25701.1 - 0.23 9.9 1.5 0.23 9.8 0.4 1.3 2 0 0 2 2 2 0 AAA domain DUF4407 PF14362.1 OAJ25701.1 - 0.38 9.6 7.0 0.32 9.9 2.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) BRE1 PF08647.6 OAJ25701.1 - 0.63 10.0 5.4 0.5 10.3 1.6 2.2 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase EAP30 PF04157.11 OAJ25702.1 - 4.2e-28 98.0 1.2 1.5e-27 96.2 0.8 1.9 1 1 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 OAJ25702.1 - 2e-23 82.0 0.0 4.1e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 OAJ25702.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 GRAM domain zf-RanBP PF00641.13 OAJ25702.1 - 0.22 10.6 1.7 0.42 9.7 1.2 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.1 OAJ25702.1 - 0.25 10.6 0.6 0.45 9.7 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Rubredoxin PF00301.15 OAJ25702.1 - 0.54 10.1 4.1 0.26 11.2 0.7 2.0 1 1 0 1 1 1 0 Rubredoxin SKG6 PF08693.5 OAJ25703.1 - 0.034 13.4 9.9 0.077 12.3 6.8 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HHH_2 PF12826.2 OAJ25703.1 - 0.049 13.5 0.4 0.08 12.8 0.3 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif Amidohydro_4 PF13147.1 OAJ25703.1 - 0.29 11.1 9.2 0.31 11.0 6.4 1.0 1 0 0 1 1 1 0 Amidohydrolase DEC-1_N PF04625.8 OAJ25703.1 - 3.5 6.1 15.8 4 6.0 11.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PLRV_ORF5 PF01690.12 OAJ25703.1 - 8.3 5.4 9.2 11 4.9 6.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein FAP PF07174.6 OAJ25703.1 - 8.6 5.5 21.5 9.4 5.4 14.9 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) HsbA PF12296.3 OAJ25704.1 - 0.00025 20.8 2.5 0.00025 20.8 1.7 1.6 2 0 0 2 2 2 1 Hydrophobic surface binding protein A CS PF04969.11 OAJ25705.1 - 3.6e-20 72.3 0.1 6e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 CS domain Dala_Dala_lig_N PF01820.16 OAJ25705.1 - 0.079 13.2 0.4 0.24 11.7 0.0 1.9 2 1 0 2 2 2 0 D-ala D-ala ligase N-terminus CLU PF13236.1 OAJ25706.1 - 8.4e-67 224.8 0.0 2.2e-66 223.4 0.0 1.7 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.2 OAJ25706.1 - 6.4e-43 146.6 0.0 1.6e-42 145.3 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 OAJ25706.1 - 1e-17 63.7 6.0 9.6e-09 35.0 0.7 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ25706.1 - 8.8e-06 25.2 0.7 7.5e-05 22.3 0.3 2.7 3 0 0 3 3 3 1 TPR repeat CLU_N PF15044.1 OAJ25706.1 - 1.1e-05 25.5 0.3 7.9e-05 22.7 0.0 2.5 2 1 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_1 PF00515.23 OAJ25706.1 - 0.00015 21.1 0.2 0.0053 16.3 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ25706.1 - 0.0015 18.1 1.2 0.13 12.0 0.1 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ25706.1 - 0.0021 17.9 18.7 0.013 15.4 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ25706.1 - 0.0056 16.5 1.7 0.77 9.8 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ25706.1 - 0.02 14.6 0.1 0.086 12.6 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ25706.1 - 0.091 13.4 0.1 0.091 13.4 0.1 4.3 3 1 1 4 4 3 0 Tetratricopeptide repeat DASH_Dad1 PF08649.5 OAJ25707.1 - 1.1e-19 69.8 0.2 1.4e-19 69.5 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Pinin_SDK_N PF04697.8 OAJ25708.1 - 0.06 13.3 0.1 0.076 13.0 0.0 1.2 1 0 0 1 1 1 0 pinin/SDK conserved region Mito_carr PF00153.22 OAJ25711.1 - 7.5e-57 189.0 4.2 2.3e-19 68.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mitochondr_Som1 PF11093.3 OAJ25712.1 - 3.1e-06 26.9 0.3 4.5e-06 26.3 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Dynamin_M PF01031.15 OAJ25713.1 - 3.7e-15 55.4 0.0 3.8e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Dynamin central region Dynamin_M PF01031.15 OAJ25714.1 - 1.6e-11 43.5 0.0 1.8e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region CorA PF01544.13 OAJ25715.1 - 4.3e-20 71.9 3.1 5e-11 42.1 0.1 3.3 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF3605 PF12239.3 OAJ25716.1 - 4.1e-23 81.9 0.6 1.5e-18 67.1 0.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) DUF605 PF04652.11 OAJ25716.1 - 0.33 10.2 13.3 0.45 9.8 9.2 1.2 1 0 0 1 1 1 0 Vta1 like CAF-1_p150 PF11600.3 OAJ25716.1 - 3.5 6.9 11.1 5.4 6.3 7.7 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AF-4 PF05110.8 OAJ25716.1 - 6.5 4.4 17.9 8.8 4.0 12.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein THRAP3_BCLAF1 PF15440.1 OAJ25716.1 - 9.1 4.8 12.3 12 4.3 8.5 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Bromodomain PF00439.20 OAJ25717.1 - 2.7e-22 78.4 0.2 4.9e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 OAJ25717.1 - 2.2e-06 27.3 0.2 7.6e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 Bromodomain associated DUF2361 PF10153.4 OAJ25718.1 - 7.2e-18 64.8 5.3 2.1e-17 63.3 3.7 1.8 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2361) Sigma70_ner PF04546.8 OAJ25718.1 - 0.83 9.2 20.3 2.7 7.5 2.4 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Spt5_N PF11942.3 OAJ25718.1 - 1.3 9.7 18.3 0.084 13.4 5.5 3.1 2 1 1 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal NOA36 PF06524.7 OAJ25718.1 - 2.5 7.2 6.7 4.7 6.3 4.7 1.4 1 0 0 1 1 1 0 NOA36 protein CCDC-167 PF15188.1 OAJ25718.1 - 3.8 7.5 6.0 0.66 9.9 0.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Rad60-SLD_2 PF13881.1 OAJ25719.1 - 1.5e-10 40.9 0.0 2.8e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MTBP_C PF14920.1 OAJ25719.1 - 0.93 8.9 5.5 1.5 8.2 3.8 1.3 1 0 0 1 1 1 0 MDM2-binding Mucin PF01456.12 OAJ25719.1 - 1.8 8.3 8.7 3 7.6 6.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Dynamin_N PF00350.18 OAJ25720.1 - 1.5e-23 83.4 0.0 2.1e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 OAJ25720.1 - 4.4e-21 74.9 0.0 6.3e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region zf-C2H2_jaz PF12171.3 OAJ25721.1 - 2.5e-07 30.6 0.1 3.8e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAJ25721.1 - 4.5e-05 23.4 0.2 7.1e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 OAJ25721.1 - 0.00021 20.9 0.0 0.00043 19.8 0.0 1.5 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2 PF00096.21 OAJ25721.1 - 0.16 12.4 0.7 0.28 11.6 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type CAF-1_p150 PF11600.3 OAJ25721.1 - 0.54 9.5 25.9 0.09 12.1 8.7 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Phosducin PF02114.11 OAJ25722.1 - 6.5e-15 54.5 0.2 6.8e-07 28.2 0.0 3.3 3 0 0 3 3 3 3 Phosducin FAM176 PF14851.1 OAJ25722.1 - 3 7.5 10.9 2.8 7.6 1.4 3.2 3 0 0 3 3 3 0 FAM176 family PA_decarbox PF05870.6 OAJ25723.1 - 4.3e-26 91.3 0.7 4.9e-26 91.1 0.5 1.0 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) MoaF PF10703.4 OAJ25723.1 - 7.5e-06 25.2 0.4 1e-05 24.7 0.3 1.2 1 0 0 1 1 1 1 Molybdenum cofactor biosynthesis protein F 2-Hacid_dh_C PF02826.14 OAJ25724.1 - 8.5e-37 126.0 0.0 6.3e-36 123.1 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 OAJ25724.1 - 8.9e-05 22.6 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh PF00389.25 OAJ25724.1 - 0.0064 15.9 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Rhomboid PF01694.17 OAJ25726.1 - 7.3e-09 35.7 13.7 0.00023 21.2 0.2 2.8 2 1 0 2 2 2 2 Rhomboid family PIG-L PF02585.12 OAJ25728.1 - 1.8e-25 89.9 0.6 2.6e-25 89.3 0.4 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glyco_hydro_20 PF00728.17 OAJ25729.1 - 1.3e-78 264.6 0.0 1.6e-78 264.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 OAJ25729.1 - 4.5e-15 56.4 0.0 7.5e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 OAJ25729.1 - 0.0015 19.0 0.4 0.02 15.3 0.3 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 SDA1 PF05285.7 OAJ25730.1 - 0.084 12.1 6.9 0.12 11.6 4.8 1.1 1 0 0 1 1 1 0 SDA1 Spt5_N PF11942.3 OAJ25730.1 - 2.2 8.9 15.5 4.6 7.9 1.4 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RXT2_N PF08595.6 OAJ25730.1 - 3.6 7.3 8.8 12 5.6 5.7 1.9 1 1 1 2 2 2 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 OAJ25730.1 - 3.8 7.0 10.7 5.4 6.5 2.4 2.3 2 0 0 2 2 2 0 Nucleoplasmin DUF2456 PF10445.4 OAJ25731.1 - 3.7e-22 78.0 2.1 3.7e-22 78.0 1.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) AIG2 PF06094.7 OAJ25733.1 - 1e-11 45.1 0.0 1.7e-11 44.5 0.0 1.4 1 1 0 1 1 1 1 AIG2-like family ArfGap PF01412.13 OAJ25734.1 - 1.2e-32 112.1 0.5 3e-32 110.8 0.0 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Lon_C PF05362.8 OAJ25736.1 - 7.8e-65 218.0 0.1 1.4e-64 217.2 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 OAJ25736.1 - 9.7e-23 80.8 0.0 2.4e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAJ25736.1 - 2.6e-09 36.9 0.0 1.9e-08 34.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 OAJ25736.1 - 5.6e-09 35.5 0.0 1.2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase LON PF02190.11 OAJ25736.1 - 1.7e-06 27.9 0.0 3.9e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA_16 PF13191.1 OAJ25736.1 - 5.1e-05 23.3 0.1 5.1e-05 23.3 0.1 2.7 2 2 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 OAJ25736.1 - 7.3e-05 23.5 0.0 0.00028 21.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ25736.1 - 0.00033 20.5 0.2 0.011 15.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 OAJ25736.1 - 0.00048 20.0 0.0 0.0022 17.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 OAJ25736.1 - 0.00058 20.0 0.2 0.012 15.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 OAJ25736.1 - 0.0053 17.0 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAJ25736.1 - 0.0097 15.3 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 OAJ25736.1 - 0.012 14.6 0.0 0.036 13.1 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 OAJ25736.1 - 0.015 14.4 0.1 0.041 13.0 0.0 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 OAJ25736.1 - 0.015 15.0 2.2 0.017 14.8 0.3 2.1 2 0 0 2 2 1 0 Part of AAA domain RNA_helicase PF00910.17 OAJ25736.1 - 0.022 14.9 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 OAJ25736.1 - 0.023 14.2 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_PrkA PF08298.6 OAJ25736.1 - 0.035 12.8 0.0 0.62 8.6 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_14 PF13173.1 OAJ25736.1 - 0.05 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 OAJ25736.1 - 0.054 12.6 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.7 OAJ25736.1 - 0.065 12.8 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 OAJ25736.1 - 0.076 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 OAJ25736.1 - 0.17 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 OAJ25736.1 - 0.19 10.9 0.0 0.34 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 OAJ25736.1 - 0.74 10.1 0.0 0.74 10.1 0.0 2.5 2 1 1 3 3 2 0 AAA domain Aminotran_5 PF00266.14 OAJ25737.1 - 1.5e-19 69.9 0.0 1.7e-18 66.5 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 OAJ25737.1 - 0.0084 15.1 0.0 0.013 14.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II SMN PF06003.7 OAJ25738.1 - 0.011 14.8 3.0 0.016 14.2 2.1 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) CDC45 PF02724.9 OAJ25738.1 - 0.11 10.5 6.5 0.097 10.6 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 OAJ25738.1 - 0.48 10.2 7.8 0.73 9.6 5.4 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.7 OAJ25738.1 - 0.85 7.4 14.1 1.2 7.0 9.8 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 OAJ25738.1 - 0.99 7.8 14.2 1.3 7.4 9.9 1.2 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 OAJ25738.1 - 2.3 5.9 8.2 2.8 5.6 5.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 OAJ25738.1 - 3.3 8.0 11.2 7.2 6.9 7.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CobT PF06213.7 OAJ25738.1 - 4 6.4 14.8 5.6 6.0 10.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 OAJ25738.1 - 4.6 6.8 12.1 6.9 6.2 8.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1510 PF07423.6 OAJ25738.1 - 5.6 6.2 10.2 8 5.7 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2457 PF10446.4 OAJ25738.1 - 7 5.2 18.8 10 4.7 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pkinase PF00069.20 OAJ25739.1 - 1.4e-40 139.0 0.4 2.7e-23 82.4 0.3 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ25739.1 - 1.1e-11 44.2 0.6 5.7e-09 35.4 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 OAJ25739.1 - 0.24 10.1 0.0 0.34 9.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase p450 PF00067.17 OAJ25740.1 - 1.5e-71 241.3 0.0 5.8e-44 150.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 ABC_trans_N PF14510.1 OAJ25740.1 - 0.085 12.9 0.1 0.36 10.9 0.0 2.1 3 0 0 3 3 3 0 ABC-transporter extracellular N-terminal tRNA-synt_1 PF00133.17 OAJ25741.1 - 8.2e-52 176.0 0.3 9.2e-52 175.8 0.2 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 OAJ25741.1 - 1.7e-05 23.6 0.8 2.8e-05 22.9 0.5 1.4 1 1 1 2 2 2 1 tRNA synthetases class I (M) RNase_H PF00075.19 OAJ25742.1 - 0.0018 18.6 0.0 0.0043 17.3 0.0 1.6 2 0 0 2 2 2 1 RNase H RVT_3 PF13456.1 OAJ25742.1 - 0.0025 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like RVT_1 PF00078.22 OAJ25742.1 - 0.023 14.0 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.17 OAJ25743.1 - 0.00029 20.5 0.0 0.0006 19.5 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 OAJ25743.1 - 0.0068 16.5 0.0 0.027 14.6 0.0 2.0 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DUF3440 PF11922.3 OAJ25743.1 - 0.045 13.3 0.0 0.61 9.6 0.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF3440) Phage_int_SAM_4 PF13495.1 OAJ25743.1 - 0.087 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Ammonium_transp PF00909.16 OAJ25749.1 - 2.2e-104 349.1 29.3 2.8e-104 348.7 20.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family YqzM PF14141.1 OAJ25749.1 - 0.042 13.6 0.2 0.15 11.8 0.1 1.9 1 0 0 1 1 1 0 YqzM-like protein YCII PF03795.9 OAJ25750.1 - 0.006 16.7 0.0 0.021 14.9 0.0 1.9 1 0 0 1 1 1 1 YCII-related domain Pap_E4 PF02711.9 OAJ25750.1 - 3.8 8.3 5.3 0.71 10.7 0.8 1.9 2 0 0 2 2 2 0 E4 protein Serglycin PF04360.7 OAJ25750.1 - 4.1 7.1 24.7 78 2.9 0.0 2.7 2 1 1 3 3 3 0 Serglycin ER_lumen_recept PF00810.13 OAJ25751.1 - 1.3e-50 171.6 4.3 1.8e-50 171.2 3.0 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 OAJ25751.1 - 0.0048 16.4 0.8 0.0048 16.4 0.6 4.0 4 0 0 4 4 4 2 PQ loop repeat Mago_nashi PF02792.9 OAJ25752.1 - 3.3e-74 247.3 0.4 3.8e-74 247.1 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Apc4 PF12896.2 OAJ25753.1 - 3e-21 75.6 0.0 6e-21 74.7 0.0 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Hexapep PF00132.19 OAJ25754.1 - 3.6e-10 38.8 10.7 9.6e-08 31.1 4.7 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 OAJ25754.1 - 4.2e-10 39.4 0.0 9.7e-10 38.3 0.0 1.6 1 1 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 OAJ25754.1 - 1.4e-07 30.9 8.9 2.5e-07 30.1 5.3 2.0 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase CytochromB561_N PF09786.4 OAJ25755.1 - 0.057 11.8 1.6 0.054 11.9 1.1 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal GMC_oxred_N PF00732.14 OAJ25756.1 - 6.9e-40 137.0 0.0 1.1e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ25756.1 - 3.1e-21 76.1 0.7 1.5e-19 70.7 0.5 2.9 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 OAJ25756.1 - 1e-08 34.5 0.9 3e-05 23.0 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 OAJ25756.1 - 2.2e-05 24.3 0.5 7.7e-05 22.6 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ25756.1 - 0.00012 21.1 2.4 0.00027 19.9 0.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAJ25756.1 - 0.00044 19.4 0.3 0.00067 18.8 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAJ25756.1 - 0.0014 18.5 0.8 0.0082 16.0 0.3 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ25756.1 - 0.009 15.1 0.2 0.016 14.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 OAJ25756.1 - 0.022 13.2 0.3 0.044 12.2 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 OAJ25756.1 - 0.033 13.1 0.1 0.054 12.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.2 OAJ25756.1 - 0.04 12.9 0.9 0.062 12.3 0.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 OAJ25756.1 - 0.12 11.7 0.6 0.22 10.9 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 OAJ25756.1 - 0.15 10.9 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A WD40 PF00400.27 OAJ25757.1 - 2.1e-62 204.9 24.1 2.7e-11 42.8 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 OAJ25757.1 - 5.4e-05 21.5 7.5 0.058 11.5 0.2 3.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 OAJ25757.1 - 0.0016 18.1 0.0 0.0072 16.0 0.0 2.0 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 OAJ25757.1 - 0.07 11.4 0.0 3.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.7 OAJ25757.1 - 0.52 10.0 3.4 41 3.9 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF1764 PF08576.5 OAJ25759.1 - 5.9e-18 65.5 22.9 8.9e-18 64.9 4.0 2.6 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) DUF3484 PF11983.3 OAJ25759.1 - 0.55 11.0 13.3 0.073 13.9 5.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3484) DUF966 PF06136.8 OAJ25759.1 - 0.95 8.8 14.2 1.2 8.4 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Consortin_C PF15281.1 OAJ25759.1 - 1.7 8.1 5.7 1.4 8.4 2.3 2.0 1 1 2 3 3 3 0 Consortin C-terminus DUF1510 PF07423.6 OAJ25759.1 - 4.2 6.6 17.5 5.3 6.3 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CMV_1a PF12467.3 OAJ25759.1 - 6.7 7.0 13.6 8.7 6.6 9.4 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Macoilin PF09726.4 OAJ25759.1 - 9.1 4.4 12.4 11 4.1 8.6 1.1 1 0 0 1 1 1 0 Transmembrane protein HA2 PF04408.18 OAJ25760.1 - 1.7e-14 53.6 0.4 7.7e-14 51.5 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ25760.1 - 8.7e-12 44.7 0.1 2.6e-11 43.2 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 OAJ25760.1 - 1.7e-07 31.7 5.5 0.00029 21.3 0.2 3.0 3 0 0 3 3 3 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.11 OAJ25760.1 - 1.4e-06 28.1 0.0 3.2e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 OAJ25760.1 - 6.7e-06 25.6 0.0 1.7e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase bZIP_1 PF00170.16 OAJ25761.1 - 1.1e-05 25.2 6.8 2.3e-05 24.2 4.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAJ25761.1 - 0.00013 21.6 3.7 0.00033 20.4 2.6 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Alginate_lyase PF05426.7 OAJ25762.1 - 1.8e-49 168.5 5.7 4.1e-48 164.0 1.1 2.3 2 0 0 2 2 2 2 Alginate lyase JmjC PF02373.17 OAJ25763.1 - 4.1e-38 130.1 0.5 7.6e-38 129.2 0.3 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 OAJ25763.1 - 1.8e-12 46.5 0.6 3.5e-12 45.6 0.4 1.5 1 0 0 1 1 1 1 jmjN domain DUF4463 PF14703.1 OAJ25763.1 - 0.0041 17.6 0.1 0.022 15.2 0.1 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF155 PF02582.9 OAJ25764.1 - 4.9e-33 114.4 0.0 1.4e-16 60.9 0.0 2.8 2 1 1 3 3 3 2 Uncharacterised ACR, YagE family COG1723 TFIIA PF03153.8 OAJ25764.1 - 0.86 9.4 19.6 1.7 8.4 13.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 OAJ25764.1 - 2.8 6.0 32.6 4.4 5.4 22.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UTP15_C PF09384.5 OAJ25765.1 - 1.8e-36 125.0 0.0 2.9e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 OAJ25765.1 - 1.9e-29 100.4 4.0 3.1e-10 39.5 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat G_glu_transpept PF01019.16 OAJ25766.1 - 4.4e-140 467.5 0.0 5.4e-140 467.2 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase ANTH PF07651.11 OAJ25767.1 - 4.7e-70 235.4 0.2 4.7e-70 235.4 0.1 2.5 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.12 OAJ25767.1 - 2.4e-62 209.3 10.0 2.4e-62 209.3 6.9 4.7 5 1 0 5 5 5 1 I/LWEQ domain ENTH PF01417.15 OAJ25767.1 - 3.2e-08 33.4 2.0 4.2e-07 29.8 0.0 3.7 3 1 1 4 4 4 1 ENTH domain FlaC_arch PF05377.6 OAJ25767.1 - 5 7.1 11.3 2.5 8.0 0.4 4.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ETF PF01012.16 OAJ25770.1 - 3e-40 137.6 5.6 5.9e-40 136.6 3.9 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 OAJ25770.1 - 1.6e-35 120.5 1.8 2.4e-35 119.9 0.4 2.0 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain BMC PF00936.14 OAJ25770.1 - 0.0035 16.9 0.9 0.0035 16.9 0.6 2.6 2 0 0 2 2 2 1 BMC domain CRAL_TRIO PF00650.15 OAJ25771.1 - 7.5e-24 84.0 0.0 1e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ25771.1 - 2.5e-05 24.3 0.0 6.5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RNase_P_p30 PF01876.11 OAJ25772.1 - 3.8e-33 113.8 0.0 5.6e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 SAGA-Tad1 PF12767.2 OAJ25772.1 - 0.017 14.8 5.7 0.031 13.9 4.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit EMP24_GP25L PF01105.19 OAJ25773.1 - 1.8e-39 135.3 0.1 2.1e-39 135.1 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD LysM PF01476.15 OAJ25774.1 - 4.9e-12 45.5 0.0 1.7e-06 27.8 0.0 2.6 3 0 0 3 3 3 2 LysM domain RskA PF10099.4 OAJ25774.1 - 0.083 12.6 4.9 0.14 11.9 3.4 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3040 PF11239.3 OAJ25774.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF3357 PF11837.3 OAJ25774.1 - 1.9 8.4 7.3 5.6 6.8 4.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Cytochrom_C PF00034.16 OAJ25775.1 - 8.6e-10 39.3 0.1 1.5e-09 38.5 0.1 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 OAJ25775.1 - 1e-07 31.9 2.2 1.4e-06 28.3 1.6 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 OAJ25775.1 - 0.0011 18.4 0.1 0.0088 15.4 0.0 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain Haem_bd PF14376.1 OAJ25775.1 - 0.062 12.9 0.2 0.93 9.1 0.0 2.1 2 0 0 2 2 2 0 Haem-binding domain eRF1_2 PF03464.10 OAJ25776.1 - 3.9e-43 146.9 0.0 6.3e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 OAJ25776.1 - 3e-37 127.3 0.1 5.8e-37 126.4 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 OAJ25776.1 - 1.8e-25 89.0 0.0 3.1e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 EOS1 PF12326.3 OAJ25777.1 - 1.9e-17 63.3 0.0 3.7e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 N-glycosylation protein Serglycin PF04360.7 OAJ25777.1 - 0.0031 17.2 4.6 0.0031 17.2 3.2 6.2 5 1 1 6 6 6 1 Serglycin ARL6IP6 PF15062.1 OAJ25777.1 - 1.4 8.8 7.5 1.4 8.8 0.5 2.9 1 1 0 2 2 2 0 Haemopoietic lineage transmembrane helix Ion_trans PF00520.26 OAJ25782.1 - 1.5e-103 344.3 81.6 4.6e-34 117.4 8.2 5.2 5 0 0 5 5 5 4 Ion transport protein EF-hand_1 PF00036.27 OAJ25782.1 - 0.015 14.5 0.0 0.041 13.2 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 OAJ25782.1 - 0.032 14.1 0.0 0.13 12.2 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain WD40 PF00400.27 OAJ25783.1 - 0.00045 19.9 2.9 0.0043 16.8 0.0 3.4 4 0 0 4 4 4 1 WD domain, G-beta repeat Methyltransf_12 PF08242.7 OAJ25784.1 - 1.8e-06 28.3 0.0 3.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ25784.1 - 9.7e-06 26.1 0.0 1.7e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ25784.1 - 4.7e-05 23.1 0.0 0.00017 21.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ25784.1 - 0.00011 22.5 0.0 0.00021 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ25784.1 - 0.0019 17.8 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ25784.1 - 0.032 14.5 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Synaptobrevin PF00957.16 OAJ25785.1 - 2.2e-14 52.7 1.3 2.2e-14 52.7 0.9 1.7 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.1 OAJ25785.1 - 3.6e-14 52.0 0.0 1.1e-13 50.4 0.0 1.8 2 0 0 2 2 2 1 Regulated-SNARE-like domain DUF500 PF04366.7 OAJ25786.1 - 5.1e-40 135.8 0.0 1.1e-39 134.7 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF500) APC_CDC26 PF10471.4 OAJ25786.1 - 0.00038 21.1 6.7 0.023 15.4 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex APC subunit 1 SH3BGR PF04908.10 OAJ25787.1 - 3.5e-16 58.9 0.0 4.5e-08 32.9 0.0 3.2 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 OAJ25787.1 - 0.62 10.0 1.5 59 3.7 0.0 3.5 4 0 0 4 4 4 0 Glutaredoxin HSP70 PF00012.15 OAJ25788.1 - 2.2e-270 897.7 8.5 2.6e-270 897.5 5.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAJ25788.1 - 6.6e-16 57.8 0.5 1.3e-14 53.5 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 OAJ25788.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 OAJ25788.1 - 0.011 14.9 0.2 0.034 13.2 0.2 1.9 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FtsA PF14450.1 OAJ25788.1 - 0.013 15.3 3.8 4.1 7.2 0.2 3.4 2 2 0 2 2 2 0 Cell division protein FtsA NeA_P2 PF12312.3 OAJ25789.1 - 2.2 7.4 7.8 0.86 8.7 0.6 2.1 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein SMN PF06003.7 OAJ25789.1 - 8.6 5.3 8.9 10 5.1 6.2 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Rubredoxin PF00301.15 OAJ25790.1 - 0.057 13.3 1.4 2.4 8.1 0.1 2.6 2 0 0 2 2 2 0 Rubredoxin FYVE_2 PF02318.11 OAJ25790.1 - 0.19 11.6 2.3 1.2 9.1 0.1 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger DZR PF12773.2 OAJ25790.1 - 0.38 10.6 3.6 0.61 9.9 0.2 2.1 2 0 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 OAJ25790.1 - 3.7 7.4 6.4 18 5.2 4.4 2.0 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-AD PF07776.10 OAJ25790.1 - 3.8 7.5 5.6 1.4 8.9 0.3 2.0 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) SIR2 PF02146.12 OAJ25791.1 - 6.4e-54 182.3 0.0 9.9e-54 181.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family MRP-S31 PF15433.1 OAJ25793.1 - 0.011 15.1 13.0 0.013 14.9 9.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF2722 PF10846.3 OAJ25793.1 - 0.51 9.3 25.6 0.64 8.9 17.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.8 OAJ25793.1 - 0.54 10.0 23.8 0.74 9.6 16.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S64 PF08192.6 OAJ25793.1 - 1.5 7.0 13.2 1.7 6.8 9.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF4106 PF13388.1 OAJ25793.1 - 2.2 7.1 22.2 2.9 6.7 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) RR_TM4-6 PF06459.7 OAJ25793.1 - 2.9 7.7 6.8 3.6 7.4 4.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Retinal PF15449.1 OAJ25793.1 - 5.4 4.5 31.5 6.5 4.2 21.8 1.0 1 0 0 1 1 1 0 Retinal protein Presenilin PF01080.12 OAJ25793.1 - 5.9 5.5 10.3 8.2 5.1 7.2 1.2 1 0 0 1 1 1 0 Presenilin Kinesin PF00225.18 OAJ25794.1 - 1.2e-97 326.6 5.5 1.6e-52 178.2 0.0 4.1 4 0 0 4 4 4 2 Kinesin motor domain Spc7 PF08317.6 OAJ25794.1 - 5.2e-05 22.0 8.4 5.2e-05 22.0 5.8 11.5 6 2 4 12 12 12 6 Spc7 kinetochore protein Methyltransf_16 PF10294.4 OAJ25795.1 - 0.00025 20.5 0.0 0.046 13.1 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_12 PF08242.7 OAJ25795.1 - 0.0016 18.8 0.0 0.18 12.2 0.0 3.2 2 1 1 3 3 3 1 Methyltransferase domain BAF1_ABF1 PF04684.8 OAJ25795.1 - 0.011 14.6 0.7 0.019 13.8 0.5 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 OAJ25795.1 - 0.037 13.0 0.9 0.04 12.9 0.0 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter LRS4 PF10422.4 OAJ25795.1 - 0.37 10.1 3.1 0.84 8.9 2.1 1.6 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 ECH PF00378.15 OAJ25797.1 - 7e-17 61.3 0.0 1.4e-16 60.3 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Rhodanese PF00581.15 OAJ25799.1 - 9.3e-08 32.4 0.0 1.3e-07 31.9 0.0 1.3 1 1 0 1 1 1 1 Rhodanese-like domain Methyltransf_16 PF10294.4 OAJ25800.1 - 4.4e-18 65.3 0.0 1.5e-16 60.2 0.0 2.3 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 OAJ25800.1 - 2.4e-05 24.8 0.0 5.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ25800.1 - 0.0015 18.5 0.1 0.0046 16.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 OAJ25800.1 - 0.0029 17.0 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 OAJ25800.1 - 0.0076 16.6 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ25800.1 - 0.059 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ25800.1 - 0.063 13.7 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain COP-gamma_platf PF08752.5 OAJ25800.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Coatomer gamma subunit appendage platform subdomain DREV PF05219.7 OAJ25800.1 - 0.19 10.5 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Pkinase PF00069.20 OAJ25801.1 - 1.5e-64 217.6 0.0 1.5e-34 119.3 0.0 3.5 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ25801.1 - 2e-31 109.0 0.0 1.2e-15 57.2 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 OAJ25801.1 - 5.1e-17 61.7 0.0 1.2e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 OAJ25801.1 - 1.4e-13 50.6 0.8 5.2e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase HGTP_anticodon2 PF12745.2 OAJ25801.1 - 3.8e-13 49.2 0.0 3.8e-13 49.2 0.0 2.4 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs APH PF01636.18 OAJ25801.1 - 1.3e-06 28.3 0.0 1.3e-06 28.3 0.0 3.6 4 2 0 4 4 4 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ25801.1 - 2.8e-05 23.2 0.0 0.00038 19.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like CHD5 PF04420.9 OAJ25802.1 - 3e-39 134.2 0.0 3.4e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 CHD5-like protein TB2_DP1_HVA22 PF03134.14 OAJ25803.1 - 3.7e-22 77.8 7.7 3e-19 68.5 2.5 2.4 2 0 0 2 2 2 2 TB2/DP1, HVA22 family Ribosomal_L6 PF00347.18 OAJ25807.1 - 5e-24 84.5 3.1 2.5e-11 43.9 0.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Cupin_5 PF06172.6 OAJ25808.1 - 5.7e-15 55.4 0.0 5.4e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily (DUF985) GATA PF00320.22 OAJ25809.1 - 1.5e-14 53.0 8.5 3.2e-14 51.9 5.9 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 OAJ25809.1 - 0.011 15.0 1.5 0.022 14.0 1.0 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Zip PF02535.17 OAJ25809.1 - 0.033 13.1 8.4 0.051 12.5 5.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter zf-ribbon_3 PF13248.1 OAJ25809.1 - 0.083 12.1 1.1 0.18 11.0 0.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain RRN7 PF11781.3 OAJ25809.1 - 0.29 10.6 1.2 0.59 9.6 0.8 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Ion_trans_2 PF07885.11 OAJ25819.1 - 6.7e-32 109.0 26.6 3.6e-16 58.6 7.4 2.5 2 0 0 2 2 2 2 Ion channel Lig_chan PF00060.21 OAJ25819.1 - 1.2 8.8 8.4 6.2 6.5 1.8 2.8 2 1 0 2 2 2 0 Ligand-gated ion channel zf-C3HC4 PF00097.20 OAJ25820.1 - 3.1e-06 26.7 2.3 1.9e-05 24.2 0.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ25820.1 - 2.7e-05 23.9 5.0 0.00044 20.0 0.1 2.9 3 0 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 OAJ25820.1 - 0.0037 16.9 1.8 0.037 13.7 0.3 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAJ25820.1 - 0.017 15.1 1.9 0.017 15.1 1.3 2.9 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ25820.1 - 0.039 13.6 6.7 0.17 11.6 0.3 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.1 OAJ25820.1 - 2.9 8.0 11.9 0.081 12.9 3.0 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 OAJ25820.1 - 3.5 7.4 10.1 20 4.9 0.1 2.8 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Isy1 PF06246.7 OAJ25821.1 - 9.9e-72 241.3 3.3 3.4e-71 239.6 2.3 1.7 1 1 0 1 1 1 1 Isy1-like splicing family ADPrib_exo_Tox PF03496.9 OAJ25821.1 - 0.13 11.4 0.6 0.92 8.6 0.4 2.0 1 1 0 1 1 1 0 ADP-ribosyltransferase exoenzyme Uso1_p115_C PF04871.8 OAJ25821.1 - 0.42 10.5 3.1 22 4.9 0.1 3.3 3 1 1 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region Ribosomal_L37 PF08561.5 OAJ25824.1 - 4e-21 74.3 3.7 4e-21 74.3 2.6 3.7 3 1 0 3 3 3 1 Mitochondrial ribosomal protein L37 Peptidase_S8 PF00082.17 OAJ25825.1 - 1.2e-42 146.0 1.4 2e-42 145.2 0.9 1.3 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.3 OAJ25825.1 - 3.4e-39 134.1 0.0 5e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II Actin PF00022.14 OAJ25826.1 - 8.5e-91 304.2 0.0 1.1e-90 303.9 0.0 1.0 1 0 0 1 1 1 1 Actin Synaptobrevin PF00957.16 OAJ25827.1 - 6e-33 112.3 1.8 6.9e-33 112.1 1.2 1.0 1 0 0 1 1 1 1 Synaptobrevin GP41 PF00517.12 OAJ25827.1 - 0.02 14.4 0.2 0.031 13.8 0.1 1.2 1 0 0 1 1 1 0 Retroviral envelope protein DUF2976 PF11190.3 OAJ25827.1 - 0.08 12.4 0.6 0.14 11.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Chitin_synth_1 PF01644.12 OAJ25828.1 - 1.1e-87 291.8 0.1 1.7e-87 291.3 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 OAJ25828.1 - 7.3e-32 108.9 0.2 1.5e-31 107.9 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 OAJ25828.1 - 2.1e-22 79.2 3.9 2.1e-20 72.6 0.0 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 OAJ25828.1 - 2e-08 34.1 0.1 2e-08 34.1 0.1 2.1 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ25828.1 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ribosomal_L30 PF00327.15 OAJ25831.1 - 2.5e-09 36.5 0.2 3.4e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_60s PF00428.14 OAJ25831.1 - 0.061 13.7 0.8 0.061 13.7 0.6 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein MOZ_SAS PF01853.13 OAJ25832.1 - 3.9e-56 189.2 0.2 6.7e-56 188.5 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family PCI_Csn8 PF10075.4 OAJ25834.1 - 2.6e-25 88.8 0.0 5e-25 87.9 0.0 1.5 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 OAJ25834.1 - 3.5e-19 69.1 0.0 5.3e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Cellulase PF00150.13 OAJ25835.1 - 2.6e-09 36.7 9.8 2.9e-09 36.5 6.2 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3357 PF11837.3 OAJ25835.1 - 0.032 14.0 1.3 0.066 13.0 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Pkinase PF00069.20 OAJ25836.1 - 1.6e-18 66.7 0.0 1e-17 64.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ25836.1 - 7.3e-06 25.2 0.1 0.00059 18.9 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 OAJ25836.1 - 0.002 17.8 1.9 0.0028 17.4 0.4 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Alpha-amylase PF00128.19 OAJ25837.1 - 9.2e-84 281.5 0.0 1.3e-83 281.0 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 OAJ25837.1 - 0.0041 16.0 0.1 0.0062 15.4 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme DUF2838 PF10998.3 OAJ25838.1 - 1.5e-37 127.8 9.6 3.7e-37 126.6 6.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) AAA_11 PF13086.1 OAJ25840.1 - 2.6e-51 174.5 5.4 9.6e-51 172.6 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_12 PF13087.1 OAJ25840.1 - 2.5e-49 167.3 0.0 7.4e-49 165.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ25840.1 - 2.3e-13 49.7 2.9 3.8e-12 45.7 0.0 3.3 3 0 0 3 3 3 1 Part of AAA domain Viral_helicase1 PF01443.13 OAJ25840.1 - 0.00022 20.8 0.0 0.4 10.1 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 OAJ25840.1 - 0.0013 18.0 0.3 1.2 8.3 0.0 2.8 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 OAJ25840.1 - 0.0015 18.0 0.0 0.52 9.7 0.0 2.5 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 OAJ25840.1 - 0.0016 18.5 0.0 0.0071 16.4 0.0 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.24 OAJ25840.1 - 0.0029 17.8 0.1 0.025 14.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 OAJ25840.1 - 0.003 17.0 0.0 0.026 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ25840.1 - 0.0035 17.3 1.2 0.016 15.1 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 OAJ25840.1 - 0.0086 16.2 0.0 0.063 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain PIF1 PF05970.9 OAJ25840.1 - 0.086 11.7 0.0 0.3 10.0 0.0 1.7 2 0 0 2 2 2 0 PIF1-like helicase AAA_23 PF13476.1 OAJ25840.1 - 0.39 11.0 8.5 0.48 10.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain Sporozoite_P67 PF05642.6 OAJ25841.1 - 4.1 5.1 13.2 5.6 4.7 6.2 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Mak10 PF04112.8 OAJ25843.1 - 6.1e-39 132.9 0.0 1.1e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF1497 PF07384.6 OAJ25844.1 - 0.14 12.3 0.1 0.19 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1497) AAA PF00004.24 OAJ25849.1 - 1e-40 139.0 0.0 2.4e-40 137.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ25849.1 - 3.3e-07 30.4 0.2 0.00027 21.0 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 OAJ25849.1 - 1.6e-06 28.2 0.2 0.00016 21.7 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 OAJ25849.1 - 2.5e-06 27.2 0.0 2.4e-05 24.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 OAJ25849.1 - 2.7e-06 26.5 0.0 4.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 OAJ25849.1 - 7.9e-06 25.7 0.0 0.0001 22.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ25849.1 - 1.3e-05 25.9 0.0 3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 OAJ25849.1 - 7.5e-05 22.6 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ25849.1 - 0.00024 21.4 0.1 0.0012 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 OAJ25849.1 - 0.00032 20.6 0.0 0.0007 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 OAJ25849.1 - 0.0004 19.8 0.0 0.00066 19.1 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 OAJ25849.1 - 0.0008 19.4 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 OAJ25849.1 - 0.0013 18.2 1.5 0.037 13.4 0.4 2.2 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 OAJ25849.1 - 0.002 16.9 0.0 0.0038 16.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 OAJ25849.1 - 0.0022 18.1 0.0 0.0063 16.6 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 OAJ25849.1 - 0.0023 17.5 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 OAJ25849.1 - 0.0028 16.8 0.2 0.0095 15.1 0.1 1.7 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.13 OAJ25849.1 - 0.0035 17.0 0.0 0.007 16.0 0.0 1.4 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_19 PF13245.1 OAJ25849.1 - 0.0035 17.0 0.5 0.0082 15.8 0.4 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 OAJ25849.1 - 0.0045 16.9 0.0 0.0082 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAJ25849.1 - 0.007 15.4 0.1 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF815 PF05673.8 OAJ25849.1 - 0.008 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_21 PF13304.1 OAJ25849.1 - 0.0087 16.0 0.5 2 8.3 0.1 2.3 1 1 1 2 2 2 1 AAA domain Arch_ATPase PF01637.13 OAJ25849.1 - 0.0087 15.7 0.8 2 8.0 0.0 3.0 2 1 1 3 3 3 1 Archaeal ATPase Sigma54_activat PF00158.21 OAJ25849.1 - 0.0098 15.3 0.0 0.021 14.2 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain KaiC PF06745.8 OAJ25849.1 - 0.015 14.4 0.0 0.13 11.3 0.0 2.1 1 1 1 2 2 2 0 KaiC Parvo_NS1 PF01057.12 OAJ25849.1 - 0.018 13.9 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 OAJ25849.1 - 0.027 13.7 0.1 0.051 12.7 0.1 1.4 1 1 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.6 OAJ25849.1 - 0.044 13.3 0.1 0.13 11.9 0.0 2.0 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) S1FA PF04689.8 OAJ25849.1 - 0.065 13.1 0.2 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA Guanylate_kin PF00625.16 OAJ25849.1 - 0.077 12.4 0.0 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Guanylate kinase DUF2075 PF09848.4 OAJ25849.1 - 0.099 11.5 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 OAJ25849.1 - 0.11 12.1 0.6 0.29 10.7 0.1 2.0 3 0 0 3 3 2 0 NACHT domain IPT PF01745.11 OAJ25849.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase UPF0079 PF02367.12 OAJ25849.1 - 0.13 11.8 0.1 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 OAJ25849.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 OAJ25849.1 - 0.14 12.4 0.1 0.21 11.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Homeobox_KN PF05920.6 OAJ25850.1 - 1e-16 60.2 3.2 2.1e-16 59.3 2.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 OAJ25850.1 - 5.6e-05 22.6 2.1 9.2e-05 21.9 0.7 1.9 2 0 0 2 2 2 1 Homeobox domain RhoGEF PF00621.15 OAJ25851.1 - 6.1e-42 143.5 0.1 1.5e-41 142.2 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 OAJ25851.1 - 5.7e-05 23.2 0.0 0.00015 21.9 0.0 1.8 1 0 0 1 1 1 1 PH domain Arteri_nucleo PF01481.11 OAJ25851.1 - 0.11 12.5 1.4 0.28 11.2 1.0 1.6 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein Cwf_Cwc_15 PF04889.7 OAJ25851.1 - 3 7.4 13.1 5.6 6.6 9.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SH3_1 PF00018.23 OAJ25852.1 - 8.4e-18 63.4 0.3 7.3e-09 34.8 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 OAJ25852.1 - 3.7e-17 61.6 0.1 8.5e-10 38.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.2 OAJ25852.1 - 4.2e-16 58.5 0.0 9.4e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_2 PF07653.12 OAJ25852.1 - 2.2e-10 39.8 0.0 2.2e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.15 OAJ25852.1 - 1.4e-07 30.8 0.3 1.4e-07 30.8 0.2 2.3 2 0 0 2 2 2 1 WH2 motif EF-hand_7 PF13499.1 OAJ25852.1 - 0.0071 16.4 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair Glyco_hydro_16 PF00722.16 OAJ25854.1 - 5.3e-06 25.8 0.0 1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Septin PF00735.13 OAJ25855.1 - 1.4e-38 132.5 0.1 1.4e-11 44.0 0.0 4.7 5 0 0 5 5 5 4 Septin TFIIA PF03153.8 OAJ25855.1 - 0.00013 22.0 15.9 0.00013 22.0 11.0 3.3 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit GTP_EFTU PF00009.22 OAJ25855.1 - 0.024 14.0 0.0 7.5 5.9 0.0 3.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Nop25 PF09805.4 OAJ25855.1 - 0.88 9.6 45.4 0.89 9.6 25.2 2.7 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Dynamin_N PF00350.18 OAJ25855.1 - 1.4 8.7 12.0 1.6 8.5 0.0 3.8 4 0 0 4 4 4 0 Dynamin family RRN3 PF05327.6 OAJ25855.1 - 8.4 4.3 13.9 14 3.6 9.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MCM PF00493.18 OAJ25856.1 - 1.7e-139 464.2 0.0 2.3e-139 463.8 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 OAJ25856.1 - 2.1e-32 112.2 30.3 2.1e-32 112.2 21.0 2.2 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 OAJ25856.1 - 1.9e-18 67.0 0.1 6.5e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 OAJ25856.1 - 2.1e-08 33.5 0.0 7.8e-07 28.4 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 OAJ25856.1 - 4.1e-06 26.5 0.0 9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 OAJ25856.1 - 0.0005 19.6 0.0 0.0039 16.8 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAJ25856.1 - 0.013 14.9 0.0 0.099 12.1 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain DNA_gyraseB_C PF00986.16 OAJ25856.1 - 0.033 13.9 0.3 2.4 7.9 0.0 3.1 3 0 0 3 3 3 0 DNA gyrase B subunit, carboxyl terminus AAA PF00004.24 OAJ25856.1 - 0.11 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zn_ribbon_2 PF12674.2 OAJ25856.1 - 0.17 12.2 0.3 0.42 10.9 0.2 1.6 1 0 0 1 1 1 0 Putative zinc ribbon domain DHBP_synthase PF00926.14 OAJ25857.1 - 1.9e-69 232.7 0.0 2.3e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase PEP-utilizers PF00391.18 OAJ25857.1 - 0.031 13.8 0.0 0.08 12.5 0.0 1.7 1 1 0 1 1 1 0 PEP-utilising enzyme, mobile domain zf-RING_2 PF13639.1 OAJ25858.1 - 1.5e-10 40.7 3.4 2.5e-10 40.0 2.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAJ25858.1 - 1.2e-08 34.8 0.9 2.1e-08 34.1 0.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 OAJ25858.1 - 8.8e-06 25.4 0.6 1.5e-05 24.7 0.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 OAJ25858.1 - 0.00013 21.6 2.0 0.00021 20.8 1.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ25858.1 - 0.00013 21.5 1.6 0.00022 20.8 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ25858.1 - 0.00018 21.4 1.8 0.00028 20.8 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ25858.1 - 0.00018 21.1 2.0 0.0003 20.4 1.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 OAJ25858.1 - 0.017 14.6 1.6 0.03 13.8 1.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 OAJ25858.1 - 0.067 13.2 5.3 0.11 12.4 3.7 1.3 1 0 0 1 1 1 0 RING-like domain CarbpepA_inh PF02977.10 OAJ25858.1 - 0.17 11.5 0.6 0.35 10.4 0.4 1.4 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor RINGv PF12906.2 OAJ25858.1 - 1.3 9.1 3.9 2.3 8.3 2.7 1.3 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 OAJ25858.1 - 1.9 8.4 3.4 3.3 7.6 2.4 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SOR_SNZ PF01680.12 OAJ25859.1 - 8.2e-115 381.6 5.9 1.2e-114 381.0 4.1 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 OAJ25859.1 - 1.2e-06 27.8 7.9 3.7e-05 22.9 0.5 2.6 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 OAJ25859.1 - 0.002 17.0 0.9 0.71 8.6 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 OAJ25859.1 - 0.033 13.4 0.1 0.65 9.2 0.0 2.3 2 0 0 2 2 2 0 Histidine biosynthesis protein NMO PF03060.10 OAJ25859.1 - 0.035 13.2 4.8 0.078 12.1 0.1 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase IGPS PF00218.16 OAJ25859.1 - 0.093 11.7 0.1 0.82 8.6 0.0 2.4 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase WD40 PF00400.27 OAJ25860.1 - 0.00021 21.0 0.0 0.0013 18.5 0.0 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat Ribosomal_L22 PF00237.14 OAJ25861.1 - 5.3e-31 106.6 0.1 7.2e-31 106.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Arrestin_C PF02752.17 OAJ25862.1 - 4.6e-14 52.6 0.0 1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Cyt-b5 PF00173.23 OAJ25863.1 - 5.7e-09 35.6 0.0 8.1e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_L23eN PF03939.8 OAJ25864.1 - 8.7e-20 70.5 11.9 1.6e-19 69.6 8.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 OAJ25864.1 - 9.9e-12 44.6 0.1 2e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 MFS_1 PF07690.11 OAJ25866.1 - 1.7e-25 89.4 67.5 8.1e-20 70.8 20.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 OAJ25866.1 - 0.084 12.6 11.8 0.15 11.8 0.6 3.6 3 0 0 3 3 3 0 MFS_1 like family DUF726 PF05277.7 OAJ25868.1 - 8.9e-118 393.1 2.6 1.2e-117 392.6 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 OAJ25868.1 - 0.0018 18.0 0.5 0.0044 16.7 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family MFS_1 PF07690.11 OAJ25869.1 - 1.7e-26 92.8 30.8 1.7e-26 92.8 21.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily PBP1_TM PF14812.1 OAJ25869.1 - 1.6 9.1 12.1 6.5 7.1 0.4 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 OAJ25869.1 - 4 6.9 11.2 0.31 10.5 1.2 2.1 2 0 0 2 2 2 0 Nucleoplasmin Ytp1 PF10355.4 OAJ25870.1 - 6.1e-65 219.1 16.1 3.8e-52 177.1 11.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.4 OAJ25870.1 - 1.2e-23 82.6 4.4 1.2e-23 82.6 3.1 3.4 3 1 1 4 4 4 1 Domain of unknown function (DUF2427) Antimicrobial10 PF08105.6 OAJ25870.1 - 0.011 15.3 0.8 0.028 14.0 0.6 1.6 1 0 0 1 1 1 0 Metchnikowin family YL1 PF05764.8 OAJ25871.1 - 0.00051 19.7 0.1 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 YL1 nuclear protein HisG PF01634.13 OAJ25872.1 - 2.6e-42 144.1 0.3 3.1e-41 140.6 0.2 2.2 1 1 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 OAJ25872.1 - 4.7e-26 90.5 0.1 1e-25 89.4 0.1 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain PMI_typeI PF01238.16 OAJ25873.1 - 1.3e-53 182.3 0.0 9.4e-53 179.5 0.0 2.1 1 1 0 1 1 1 1 Phosphomannose isomerase type I Chromo PF00385.19 OAJ25874.1 - 0.047 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain BRO1 PF03097.13 OAJ25884.1 - 1.8e-103 346.1 0.0 2.9e-103 345.5 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 OAJ25884.1 - 4.4e-53 180.1 9.1 7.7e-53 179.3 6.3 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Peptidase_M50 PF02163.17 OAJ25885.1 - 2.7e-15 55.8 0.3 1e-14 53.9 0.2 1.9 2 0 0 2 2 2 1 Peptidase family M50 CAP PF00188.21 OAJ25886.1 - 5.1e-21 75.4 1.9 1e-20 74.4 1.3 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family NOT2_3_5 PF04153.13 OAJ25887.1 - 1.7e-36 125.0 2.6 3.1e-36 124.1 1.8 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Tektin PF03148.9 OAJ25887.1 - 0.061 11.8 0.1 0.099 11.1 0.1 1.3 1 0 0 1 1 1 0 Tektin family Robl_LC7 PF03259.12 OAJ25887.1 - 0.99 9.0 0.0 0.99 9.0 0.0 3.1 3 0 0 3 3 3 0 Roadblock/LC7 domain API5 PF05918.6 OAJ25887.1 - 1.9 6.8 8.4 3.3 6.0 5.8 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) TF_Zn_Ribbon PF08271.7 OAJ25888.1 - 0.1 11.9 1.2 0.25 10.6 0.8 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Glyco_hydro_88 PF07470.8 OAJ25889.1 - 5.9e-11 41.9 0.8 5.9e-10 38.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 SnoaL_4 PF13577.1 OAJ25889.1 - 0.14 12.0 1.1 0.27 11.1 0.3 1.8 2 0 0 2 2 2 0 SnoaL-like domain RRM_5 PF13893.1 OAJ25890.1 - 6e-09 35.6 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ25890.1 - 9.3e-09 34.8 0.0 1.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ25890.1 - 6.7e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 OAJ25890.1 - 0.00012 21.6 1.9 0.0002 20.9 1.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.1 OAJ25890.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Malectin_like PF12819.2 OAJ25890.1 - 0.17 10.9 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate-binding protein of the ER Prenyltrans PF00432.16 OAJ25891.1 - 4.1e-46 154.2 11.2 4.7e-11 42.0 0.0 5.7 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 OAJ25891.1 - 7.1e-23 81.1 0.0 7.5e-11 42.4 0.0 3.9 1 1 3 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 OAJ25891.1 - 6.7e-05 22.8 0.0 0.00023 21.1 0.0 1.9 2 0 0 2 2 2 1 Prenyltransferase-like Helicase_C_4 PF13871.1 OAJ25891.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Helicase_C-like PIP5K PF01504.13 OAJ25892.1 - 6.3e-82 274.4 0.0 1.7e-81 273.0 0.0 1.7 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase DDHD PF02862.12 OAJ25892.1 - 7.7 6.2 10.9 1.6 8.5 2.6 2.6 3 1 0 3 3 3 0 DDHD domain Arm PF00514.18 OAJ25893.1 - 2.1e-70 230.3 32.4 6.3e-13 48.0 0.1 12.2 11 1 2 13 13 13 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 OAJ25893.1 - 7.1e-25 87.1 11.7 2.1e-06 27.9 0.1 7.4 2 1 5 7 7 7 7 HEAT repeats HEAT PF02985.17 OAJ25893.1 - 5.6e-19 66.4 12.4 0.074 13.1 0.0 9.1 8 0 0 8 8 8 6 HEAT repeat HEAT_EZ PF13513.1 OAJ25893.1 - 6.3e-16 58.3 9.2 0.012 16.0 0.0 8.3 7 2 3 10 10 10 5 HEAT-like repeat Adaptin_N PF01602.15 OAJ25893.1 - 1.1e-10 40.4 11.9 1.7e-08 33.2 0.6 2.4 2 1 1 3 3 3 2 Adaptin N terminal region KAP PF05804.7 OAJ25893.1 - 2.5e-10 38.9 1.8 3.9e-10 38.3 1.2 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 OAJ25893.1 - 2.3e-09 36.7 11.5 2.6e-05 23.4 3.6 3.8 1 1 0 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.9 OAJ25893.1 - 4.6e-08 32.5 9.4 0.0003 19.9 0.8 4.5 1 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.3 OAJ25893.1 - 0.00031 20.6 5.3 2.8 7.9 0.1 4.8 2 1 3 5 5 5 2 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 OAJ25893.1 - 0.018 15.3 0.1 2.4 8.5 0.0 3.2 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 OAJ25893.1 - 0.021 15.2 9.8 94 3.9 0.0 7.4 9 0 0 9 9 8 0 PBS lyase HEAT-like repeat DUF3361 PF11841.3 OAJ25893.1 - 0.024 14.3 8.1 0.58 9.8 0.1 3.9 2 2 1 3 3 3 0 Domain of unknown function (DUF3361) Tom37 PF10568.4 OAJ25893.1 - 0.1 12.8 3.1 3.4 8.0 0.0 4.0 5 0 0 5 5 4 0 Outer mitochondrial membrane transport complex protein YqfD PF06898.6 OAJ25893.1 - 0.12 11.0 0.0 0.23 10.1 0.0 1.4 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD IBN_N PF03810.14 OAJ25893.1 - 0.14 12.0 3.6 6 6.8 0.1 4.1 4 0 0 4 4 4 0 Importin-beta N-terminal domain Dabb PF07876.7 OAJ25894.1 - 2.8e-19 69.3 0.0 3.2e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Tmemb_cc2 PF10267.4 OAJ25895.1 - 0.0062 15.1 6.2 0.0081 14.7 4.3 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Sporozoite_P67 PF05642.6 OAJ25895.1 - 0.13 10.1 9.0 0.18 9.6 6.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.7 OAJ25895.1 - 1.1 8.9 7.4 0.073 12.7 0.5 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Macoilin PF09726.4 OAJ25895.1 - 1.4 7.0 12.5 2.3 6.3 8.7 1.3 1 0 0 1 1 1 0 Transmembrane protein Corona_nucleoca PF00937.13 OAJ25895.1 - 1.7 7.5 10.1 2.5 6.9 7.0 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF2217 PF10265.4 OAJ25895.1 - 1.8 7.2 9.0 2.6 6.7 6.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Sec3_C PF09763.4 OAJ25895.1 - 7.5 4.5 7.3 0.95 7.5 2.3 1.5 2 0 0 2 2 2 0 Exocyst complex component Sec3 Chorismate_bind PF00425.13 OAJ25896.1 - 1.1e-73 247.7 0.0 2.8e-73 246.4 0.0 1.7 2 0 0 2 2 2 1 chorismate binding enzyme GATase PF00117.23 OAJ25896.1 - 2.3e-28 98.9 0.0 2e-17 63.3 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 OAJ25896.1 - 3.2e-14 53.1 0.3 1.6e-13 50.8 0.0 2.3 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 OAJ25896.1 - 0.0072 15.7 0.0 0.59 9.5 0.0 2.3 2 0 0 2 2 2 2 Peptidase C26 DDE_Tnp_4 PF13359.1 OAJ25898.1 - 6.4e-33 113.5 0.0 9e-33 113.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ25898.1 - 1.1e-05 24.8 0.0 0.00015 21.2 0.0 2.5 2 1 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.16 OAJ25898.1 - 2.7e-05 23.8 0.3 0.00089 18.8 0.2 2.2 1 1 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.1 OAJ25898.1 - 0.0099 15.3 0.1 0.0099 15.3 0.0 2.3 2 1 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease MULE PF10551.4 OAJ25899.1 - 4.5e-08 33.1 0.2 2.4e-07 30.8 0.0 2.3 2 1 1 3 3 3 1 MULE transposase domain SWIM PF04434.12 OAJ25899.1 - 5.8e-05 22.4 1.9 0.00016 21.0 1.3 1.8 1 0 0 1 1 1 1 SWIM zinc finger DDE_Tnp_IS240 PF13610.1 OAJ25899.1 - 0.046 13.6 0.0 11 5.9 0.0 3.0 3 0 0 3 3 3 0 DDE domain Sporozoite_P67 PF05642.6 OAJ25899.1 - 0.3 8.9 3.5 0.43 8.3 2.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAP1 PF07218.6 OAJ25899.1 - 3.7 5.5 4.9 5.5 4.9 3.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_M16_C PF05193.16 OAJ25900.1 - 6e-24 84.7 0.0 1.2e-15 57.6 0.0 2.9 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 OAJ25900.1 - 1e-07 31.7 0.0 8.8e-07 28.7 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) PYRIN PF02758.11 OAJ25900.1 - 0.042 13.5 0.1 0.53 10.0 0.1 2.7 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain DUF1949 PF09186.6 OAJ25900.1 - 0.084 12.4 0.1 0.91 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) HRDC PF00570.18 OAJ25901.1 - 5.8e-05 22.7 0.1 0.46 10.2 0.0 2.5 2 0 0 2 2 2 2 HRDC domain Rubis-subs-bind PF09273.6 OAJ25901.1 - 0.00088 19.1 0.1 2.3 8.1 0.0 2.7 1 1 0 2 2 2 2 Rubisco LSMT substrate-binding Gram_pos_anchor PF00746.16 OAJ25901.1 - 0.019 14.7 0.0 10 6.0 0.0 2.7 2 0 0 2 2 2 0 Gram positive anchor Skp1_POZ PF03931.10 OAJ25901.1 - 0.13 12.3 0.0 23 5.1 0.0 2.2 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Chromo PF00385.19 OAJ25904.1 - 1.9e-06 27.4 0.6 3.3e-06 26.6 0.4 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Nucleoplasmin PF03066.10 OAJ25904.1 - 0.0095 15.4 16.7 1.1 8.7 1.0 4.2 4 0 0 4 4 4 3 Nucleoplasmin ST7 PF04184.7 OAJ25904.1 - 4.5 5.3 0.6 6.8 4.8 0.5 1.1 1 0 0 1 1 1 0 ST7 protein zf-C2H2 PF00096.21 OAJ25905.1 - 7.4e-06 25.9 17.7 5.1e-05 23.3 1.3 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAJ25905.1 - 4.4e-05 23.5 6.7 5.8e-05 23.1 1.4 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 OAJ25905.1 - 0.0026 17.9 0.9 0.0026 17.9 0.6 4.0 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAJ25905.1 - 0.034 14.3 0.1 0.034 14.3 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAJ25905.1 - 0.043 14.0 0.1 0.043 14.0 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 OAJ25905.1 - 1 9.0 3.3 0.8 9.4 1.0 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Colicin_im PF03857.8 OAJ25906.1 - 0.043 13.5 0.2 0.24 11.1 0.0 2.1 1 1 1 2 2 2 0 Colicin immunity protein Chitin_synth_1 PF01644.12 OAJ25907.1 - 2.1e-69 232.5 1.7 3.1e-69 231.9 1.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 OAJ25907.1 - 3.1e-22 78.6 0.1 2.6e-18 65.7 0.0 2.6 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 OAJ25907.1 - 4.6e-20 71.1 0.1 8.4e-20 70.2 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 OAJ25907.1 - 1.8e-08 34.3 0.4 1.8e-08 34.3 0.3 2.8 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ25907.1 - 6.7e-08 32.6 0.0 1.8e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Amino_oxidase PF01593.19 OAJ25914.1 - 2.9e-47 161.7 0.3 2.2e-46 158.9 0.2 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAJ25914.1 - 2.4e-10 40.2 0.2 5.3e-10 39.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 OAJ25914.1 - 1.4e-06 27.0 0.5 0.0023 16.4 0.2 2.3 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.19 OAJ25914.1 - 4.3e-06 25.8 0.4 0.00098 18.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAJ25914.1 - 7.9e-05 22.9 0.2 0.00075 19.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAJ25914.1 - 0.00017 20.5 0.2 0.00026 19.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 OAJ25914.1 - 0.00022 21.3 0.1 0.037 14.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAJ25914.1 - 0.00025 20.2 0.2 0.00043 19.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 OAJ25914.1 - 0.00066 18.8 0.4 0.0012 17.9 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 OAJ25914.1 - 0.0017 18.3 0.3 0.0055 16.6 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ25914.1 - 0.0024 17.6 0.2 1.9 8.2 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 OAJ25914.1 - 0.017 14.0 0.1 3.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.2 OAJ25914.1 - 0.094 11.7 0.7 0.16 11.0 0.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 OAJ25914.1 - 0.12 11.2 0.8 2.1 7.1 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A BolA PF01722.13 OAJ25916.1 - 4.5e-17 61.7 0.0 7.1e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein AAA_5 PF07728.9 OAJ25917.1 - 5.3e-115 379.3 0.1 1.5e-19 70.0 0.0 10.3 9 1 0 10 10 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 OAJ25917.1 - 7e-27 94.2 0.1 0.0039 17.3 0.0 7.9 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 OAJ25917.1 - 2e-24 85.7 0.0 7.9e-08 31.9 0.0 7.6 8 0 0 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ25917.1 - 5.1e-24 84.8 1.3 0.0069 16.5 0.0 8.3 7 0 0 7 7 6 6 AAA domain ABC_tran PF00005.22 OAJ25917.1 - 1.6e-17 64.0 0.2 0.0026 18.0 0.0 6.9 6 1 0 6 6 6 4 ABC transporter AAA_33 PF13671.1 OAJ25917.1 - 5.8e-17 61.8 2.3 0.025 14.4 0.1 8.1 6 1 0 6 6 6 4 AAA domain AAA_19 PF13245.1 OAJ25917.1 - 1.6e-16 59.7 10.1 0.054 13.2 0.0 7.1 6 0 0 6 6 6 5 Part of AAA domain Sigma54_activat PF00158.21 OAJ25917.1 - 1.1e-15 57.4 0.1 0.005 16.3 0.0 5.8 6 0 0 6 6 5 3 Sigma-54 interaction domain AAA_14 PF13173.1 OAJ25917.1 - 2.2e-15 56.7 0.0 0.0037 17.1 0.0 6.7 8 0 0 8 8 5 3 AAA domain AAA_17 PF13207.1 OAJ25917.1 - 6.9e-15 55.9 5.7 0.27 12.0 0.0 7.5 7 0 0 7 7 6 4 AAA domain AAA_18 PF13238.1 OAJ25917.1 - 1.6e-14 54.3 0.4 0.15 12.3 0.0 7.0 6 0 0 6 6 6 2 AAA domain AAA_16 PF13191.1 OAJ25917.1 - 2.6e-14 53.6 60.2 4.3e-05 23.5 0.6 12.4 11 3 0 11 11 7 5 AAA ATPase domain Sigma54_activ_2 PF14532.1 OAJ25917.1 - 5.1e-14 52.4 0.8 0.0099 15.9 0.1 6.8 6 0 0 6 6 6 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 OAJ25917.1 - 6.2e-14 51.5 1.4 0.02 14.0 0.0 7.1 6 1 0 6 6 6 2 Zeta toxin AAA_29 PF13555.1 OAJ25917.1 - 2.4e-12 46.1 1.4 0.071 12.6 0.0 6.2 6 0 0 6 6 6 3 P-loop containing region of AAA domain NACHT PF05729.7 OAJ25917.1 - 6e-12 45.5 2.5 0.0027 17.4 0.0 6.1 5 0 0 5 5 5 2 NACHT domain AAA_25 PF13481.1 OAJ25917.1 - 6.7e-12 45.2 10.5 0.087 12.2 0.0 7.1 6 0 0 6 6 6 3 AAA domain UPF0079 PF02367.12 OAJ25917.1 - 2.1e-11 43.5 1.5 0.044 13.4 0.0 6.1 6 0 0 6 6 6 2 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 OAJ25917.1 - 3e-11 43.8 0.3 1.2 9.6 0.0 7.1 7 0 0 7 7 6 2 Miro-like protein AAA_28 PF13521.1 OAJ25917.1 - 3.5e-11 43.3 6.1 0.89 9.5 0.0 7.2 6 0 0 6 6 6 2 AAA domain T2SE PF00437.15 OAJ25917.1 - 7.6e-11 41.4 6.4 0.14 10.9 0.0 6.6 6 0 0 6 6 6 2 Type II/IV secretion system protein DUF258 PF03193.11 OAJ25917.1 - 1.7e-09 37.0 1.2 0.061 12.5 0.0 5.7 6 0 0 6 6 5 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 OAJ25917.1 - 1.9e-09 37.6 0.6 1.1 9.4 0.0 6.7 6 0 0 6 6 6 1 RNA helicase MobB PF03205.9 OAJ25917.1 - 2.8e-09 36.7 2.0 0.23 11.1 0.0 6.4 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 OAJ25917.1 - 9.5e-09 34.7 6.0 0.1 11.7 0.1 7.8 8 0 0 8 8 7 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 OAJ25917.1 - 2.1e-08 33.3 1.5 0.31 9.9 0.0 6.0 7 0 0 7 7 6 1 Protein of unknown function (DUF815) PduV-EutP PF10662.4 OAJ25917.1 - 5.7e-07 29.1 2.2 0.31 10.5 0.0 5.5 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 OAJ25917.1 - 6.9e-06 25.8 1.3 5.6 6.4 0.0 5.8 6 0 0 6 6 6 0 AAA domain Arch_ATPase PF01637.13 OAJ25917.1 - 1.6e-05 24.7 0.0 3.4 7.2 0.0 5.3 6 0 0 6 6 5 0 Archaeal ATPase SRP54 PF00448.17 OAJ25917.1 - 9e-05 22.0 5.2 1.1 8.7 0.0 5.4 5 0 0 5 5 4 1 SRP54-type protein, GTPase domain cobW PF02492.14 OAJ25917.1 - 0.0001 21.7 7.3 2.2 7.6 0.0 5.4 6 0 0 6 6 5 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.2 OAJ25917.1 - 0.00011 21.4 0.0 0.2 10.7 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 MMR_HSR1 PF01926.18 OAJ25917.1 - 0.00016 21.6 0.1 13 5.7 0.0 5.8 6 0 0 6 6 5 0 50S ribosome-binding GTPase ResIII PF04851.10 OAJ25917.1 - 0.00017 21.4 0.8 2.9 7.6 0.0 4.7 5 0 0 5 5 3 1 Type III restriction enzyme, res subunit KaiC PF06745.8 OAJ25917.1 - 0.00022 20.4 0.8 5.7 5.9 0.0 4.9 5 0 0 5 5 5 0 KaiC ArgK PF03308.11 OAJ25917.1 - 0.00032 19.5 1.5 0.84 8.3 0.0 3.4 3 0 0 3 3 3 2 ArgK protein PhoH PF02562.11 OAJ25917.1 - 0.001 18.3 2.8 4.2 6.5 0.1 4.2 4 0 0 4 4 4 0 PhoH-like protein TIP49 PF06068.8 OAJ25917.1 - 0.0019 16.9 3.6 2.7 6.6 0.0 4.5 5 0 0 5 5 5 1 TIP49 C-terminus AAA_23 PF13476.1 OAJ25917.1 - 0.003 17.9 0.0 0.003 17.9 0.0 7.3 7 1 0 7 7 6 2 AAA domain NTPase_1 PF03266.10 OAJ25917.1 - 0.0037 16.9 3.8 4 7.1 0.0 5.2 5 0 0 5 5 5 0 NTPase ATP_bind_1 PF03029.12 OAJ25917.1 - 0.0075 15.8 2.3 9.6 5.6 0.0 4.5 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_6 PF12774.2 OAJ25917.1 - 0.023 14.2 0.0 35 3.8 0.0 4.3 5 0 0 5 5 4 0 Hydrolytic ATP binding site of dynein motor region D1 AAA_21 PF13304.1 OAJ25917.1 - 0.026 14.4 0.0 7.3 6.4 0.0 4.0 4 0 0 4 4 4 0 AAA domain Rad17 PF03215.10 OAJ25917.1 - 0.034 12.8 0.2 4.3 5.8 0.0 3.5 4 0 0 4 4 4 0 Rad17 cell cycle checkpoint protein Bac_DnaA PF00308.13 OAJ25917.1 - 0.048 13.3 0.0 6.5 6.3 0.0 3.2 3 0 0 3 3 2 0 Bacterial dnaA protein Herpes_Helicase PF02689.9 OAJ25917.1 - 0.56 7.8 0.0 20 2.7 0.0 2.3 2 0 0 2 2 2 0 Helicase Gtr1_RagA PF04670.7 OAJ25917.1 - 1.1 8.3 2.2 63 2.5 0.0 3.7 5 0 0 5 5 4 0 Gtr1/RagA G protein conserved region PEPCK_ATP PF01293.15 OAJ25917.1 - 1.8 6.9 0.6 3.2 6.1 0.1 1.5 2 0 0 2 2 1 0 Phosphoenolpyruvate carboxykinase Coiled-coil_56 PF09813.4 OAJ25918.1 - 0.008 16.1 0.1 0.017 15.1 0.0 1.6 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 56 DUF883 PF05957.8 OAJ25918.1 - 0.032 14.6 7.4 0.041 14.2 4.1 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Aminotran_5 PF00266.14 OAJ25918.1 - 0.047 12.4 1.3 0.064 11.9 0.9 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Late_protein_L2 PF00513.13 OAJ25918.1 - 0.06 12.1 0.5 0.071 11.9 0.3 1.1 1 0 0 1 1 1 0 Late Protein L2 ISG65-75 PF11727.3 OAJ25918.1 - 0.084 11.9 1.4 0.1 11.5 1.0 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Period_C PF12114.3 OAJ25918.1 - 0.26 10.8 8.5 0.34 10.4 5.9 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF1183 PF06682.7 OAJ25918.1 - 1.8 8.0 8.2 0.34 10.4 3.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) dCMP_cyt_deam_1 PF00383.17 OAJ25919.1 - 2.1e-11 43.3 0.1 4.1e-11 42.4 0.1 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 OAJ25919.1 - 1.1e-06 28.4 0.1 1.4e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain AMP-binding PF00501.23 OAJ25920.1 - 6e-82 275.2 0.0 8e-82 274.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ25920.1 - 0.018 15.9 0.0 0.13 13.2 0.0 2.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain DUF2636 PF11120.3 OAJ25920.1 - 0.11 11.9 0.4 0.26 10.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) Ras PF00071.17 OAJ25921.1 - 2.1e-34 118.2 0.3 2.5e-34 117.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ25921.1 - 2.9e-22 79.4 0.1 1.4e-21 77.1 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 OAJ25921.1 - 6.3e-08 32.0 0.3 8e-08 31.7 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 OAJ25921.1 - 7.7e-08 31.7 0.0 9.6e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ25921.1 - 0.00023 20.6 0.1 0.0022 17.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 OAJ25921.1 - 0.0026 16.5 7.8 0.036 12.7 0.0 2.8 1 1 2 3 3 3 2 G-protein alpha subunit MMR_HSR1 PF01926.18 OAJ25921.1 - 0.0032 17.4 0.0 0.0047 16.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 OAJ25921.1 - 0.061 12.5 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pex14_N PF04695.8 OAJ25921.1 - 0.1 12.6 1.9 0.18 11.8 1.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PHP_C PF13263.1 OAJ25921.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 PHP-associated DLIC PF05783.6 OAJ25921.1 - 7.5 5.0 9.4 2.8 6.4 0.0 2.8 1 1 1 3 3 3 0 Dynein light intermediate chain (DLIC) Utp21 PF04192.7 OAJ25922.1 - 2.6e-51 174.0 0.0 4.7e-51 173.1 0.0 1.5 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 OAJ25922.1 - 1.1e-09 37.8 7.9 0.072 13.0 0.2 7.0 8 0 0 8 8 8 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 OAJ25922.1 - 0.0085 15.8 0.0 0.21 11.3 0.0 3.2 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Apc4_WD40 PF12894.2 OAJ25922.1 - 0.089 12.3 0.0 6 6.4 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PBP1_TM PF14812.1 OAJ25922.1 - 0.094 13.0 2.0 0.26 11.6 1.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 OAJ25922.1 - 3.6 7.0 7.1 0.69 9.4 1.4 2.1 2 0 0 2 2 2 0 Nucleoplasmin SR-25 PF10500.4 OAJ25922.1 - 8.6 5.7 19.4 0.15 11.5 8.3 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ThiF PF00899.16 OAJ25923.1 - 8.2e-39 132.5 0.1 1.2e-38 132.0 0.1 1.2 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 OAJ25923.1 - 3e-22 77.9 0.0 5e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 OAJ25923.1 - 7.7e-08 32.6 0.0 3.2e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 Rhodanese-like domain NAD_binding_7 PF13241.1 OAJ25923.1 - 4.8e-06 26.7 0.0 9.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 OAJ25923.1 - 1.8e-05 24.8 0.1 4.9e-05 23.4 0.0 1.7 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 OAJ25923.1 - 0.06 12.7 0.1 0.093 12.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 OAJ25923.1 - 0.091 11.6 0.3 0.15 10.9 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GCV_H PF01597.14 OAJ25923.1 - 0.093 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein AMP-binding PF00501.23 OAJ25924.1 - 1.8e-91 306.6 0.1 3.7e-91 305.6 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ25924.1 - 3e-08 34.4 0.2 1e-07 32.7 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NARP1 PF12569.3 OAJ25925.1 - 1.6e-163 545.2 9.9 2.8e-162 541.0 6.9 2.2 1 1 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_7 PF13176.1 OAJ25925.1 - 2.5e-13 48.7 4.5 0.0056 16.3 0.0 7.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ25925.1 - 5.5e-12 45.1 32.6 0.0099 16.4 0.1 10.7 11 1 1 12 12 10 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ25925.1 - 5.9e-12 44.5 26.4 1.7e-05 24.3 0.0 10.1 11 1 0 11 11 11 3 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ25925.1 - 1.1e-11 43.7 3.0 3.5e-05 23.1 0.0 6.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ25925.1 - 1.4e-11 43.8 19.2 1.1e-05 24.9 0.1 7.3 6 2 0 7 7 6 2 TPR repeat TPR_19 PF14559.1 OAJ25925.1 - 5.4e-09 36.2 32.0 0.031 14.6 0.0 8.8 7 2 2 9 9 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ25925.1 - 1.7e-08 34.2 23.1 0.0057 16.5 0.1 7.1 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ25925.1 - 1.2e-06 28.2 6.4 0.0061 16.3 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ25925.1 - 4e-06 26.6 1.9 1.9 8.8 0.0 7.6 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ25925.1 - 7.5e-05 23.2 63.4 0.26 12.0 0.1 11.1 10 3 4 14 14 11 6 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ25925.1 - 0.006 16.9 16.8 0.02 15.3 0.1 7.0 7 1 0 7 7 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ25925.1 - 0.026 14.3 11.3 0.11 12.3 0.0 5.0 7 0 0 7 7 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 OAJ25925.1 - 0.046 13.6 0.6 29 4.6 0.0 4.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Fibrinogen_BP PF08017.6 OAJ25926.1 - 0.03 12.5 1.2 0.061 11.5 0.9 1.4 1 0 0 1 1 1 0 Fibrinogen binding protein zf-Di19 PF05605.7 OAJ25926.1 - 0.17 12.0 0.1 0.43 10.7 0.1 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Pkinase PF00069.20 OAJ25927.1 - 4e-66 222.8 0.0 5e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ25927.1 - 5.8e-29 100.9 0.0 7.9e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 OAJ25927.1 - 6.9e-13 48.8 0.6 6.9e-13 48.8 0.4 2.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 OAJ25927.1 - 7.1e-09 35.0 0.0 1.4e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 OAJ25927.1 - 1.3e-05 24.9 0.2 0.076 12.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain APH PF01636.18 OAJ25927.1 - 0.039 13.6 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRM_1 PF00076.17 OAJ25928.1 - 3.3e-18 65.0 0.1 3.3e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ25928.1 - 1.4e-12 47.2 0.0 2.8e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ25928.1 - 5.2e-12 45.5 0.0 2.6e-06 27.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 OAJ25928.1 - 0.03 14.0 0.4 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 Ish1 PF10281.4 OAJ25929.1 - 2.5e-47 158.5 24.1 4e-11 42.7 0.2 6.5 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein SAP PF02037.22 OAJ25929.1 - 0.0028 17.1 0.0 2.5 7.7 0.0 4.1 4 0 0 4 4 4 1 SAP domain LEM PF03020.10 OAJ25929.1 - 0.026 13.9 0.0 1.7 8.1 0.0 3.2 4 0 0 4 4 4 0 LEM domain HeH PF12949.2 OAJ25929.1 - 0.12 11.9 3.9 3.6 7.2 0.0 4.4 6 0 0 6 6 6 0 HeH/LEM domain GYF PF02213.11 OAJ25929.1 - 0.46 10.1 4.7 2.2 7.9 0.6 2.4 1 1 1 2 2 2 0 GYF domain Peptidase_S49 PF01343.13 OAJ25930.1 - 0.096 12.4 0.1 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 Homeobox_KN PF05920.6 OAJ25931.1 - 7.3e-11 41.5 0.0 2.4e-08 33.5 0.0 2.8 2 0 0 2 2 2 2 Homeobox KN domain Trp_DMAT PF11991.3 OAJ25931.1 - 0.0099 15.1 0.2 3.5 6.7 0.0 2.2 2 0 0 2 2 2 2 Tryptophan dimethylallyltransferase Homeobox PF00046.24 OAJ25931.1 - 0.03 13.9 0.0 3.1 7.4 0.0 2.8 2 0 0 2 2 2 0 Homeobox domain JSRP PF15312.1 OAJ25931.1 - 0.097 12.6 0.9 24 4.9 0.0 3.5 2 2 0 2 2 2 0 Junctional sarcoplasmic reticulum protein DUF2142 PF09913.4 OAJ25931.1 - 0.68 8.5 4.4 6.8 5.2 0.1 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2142) NST1 PF13945.1 OAJ25931.1 - 1.4 8.9 6.1 8.6 6.3 0.6 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator Mucin PF01456.12 OAJ25932.1 - 0.0028 17.4 17.8 0.033 13.9 6.3 2.5 2 1 0 2 2 2 2 Mucin-like glycoprotein Pescadillo_N PF06732.6 OAJ25933.1 - 7.8e-116 386.2 1.2 9.5e-116 385.9 0.0 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 OAJ25933.1 - 9.8e-10 38.4 0.0 2.3e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF2404 PF10296.4 OAJ25934.1 - 1.3e-28 98.9 0.1 2.4e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Pkinase PF00069.20 OAJ25935.1 - 3.3e-39 134.6 0.0 4.1e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ25935.1 - 6e-16 58.2 0.0 8.4e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ25935.1 - 1.8e-06 27.9 0.3 0.003 17.3 0.0 3.3 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 OAJ25935.1 - 0.022 13.5 0.1 0.032 13.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ribosomal_S21e PF01249.13 OAJ25939.1 - 1.8e-34 117.5 0.0 2e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e SpoA PF01052.15 OAJ25939.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) PUA_2 PF14306.1 OAJ25939.1 - 0.069 12.5 0.0 0.085 12.2 0.0 1.0 1 0 0 1 1 1 0 PUA-like domain Kinesin PF00225.18 OAJ25940.1 - 6.3e-111 370.2 0.0 2.2e-110 368.5 0.0 2.0 1 0 0 1 1 1 1 Kinesin motor domain Sox_N PF12444.3 OAJ25940.1 - 2.5 9.2 0.0 2.5 9.2 0.0 4.2 3 2 0 3 3 3 0 Sox developmental protein N terminal Filament PF00038.16 OAJ25940.1 - 9.8 5.5 79.6 0.16 11.4 31.6 3.8 3 1 2 5 5 5 0 Intermediate filament protein Clathrin PF00637.15 OAJ25941.1 - 1.5e-26 92.7 0.0 3.2e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS WD40 PF00400.27 OAJ25941.1 - 0.00015 21.5 1.8 0.0088 15.8 0.1 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat zf-rbx1 PF12678.2 OAJ25941.1 - 0.0019 18.2 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 OAJ25941.1 - 0.029 14.2 2.8 0.2 11.5 0.4 2.5 2 0 0 2 2 2 0 Ring finger domain NDUF_B4 PF07225.7 OAJ25942.1 - 0.012 15.4 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DUF1754 PF08555.5 OAJ25943.1 - 2.2e-12 47.4 6.0 2.2e-12 47.4 4.1 1.9 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) MelC1 PF06236.6 OAJ25943.1 - 0.072 13.0 0.3 0.098 12.6 0.2 1.3 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 PP2C_C PF07830.8 OAJ25943.1 - 0.078 13.1 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain CAML PF14963.1 OAJ25943.1 - 0.34 10.2 5.8 0.4 10.0 4.0 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Adaptin_binding PF10199.4 OAJ25943.1 - 0.42 10.8 5.4 0.57 10.4 3.7 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Hex_IIIa PF02455.11 OAJ25943.1 - 0.76 8.4 4.1 0.8 8.3 2.9 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) ICAP-1_inte_bdg PF10480.4 OAJ25943.1 - 0.88 9.3 7.5 1 9.1 5.2 1.0 1 0 0 1 1 1 0 Beta-1 integrin binding protein Macoilin PF09726.4 OAJ25943.1 - 1.2 7.3 12.0 1.4 7.1 8.3 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF2956 PF11169.3 OAJ25943.1 - 1.4 8.9 6.7 0.65 9.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) RAP1 PF07218.6 OAJ25943.1 - 3.1 5.7 8.7 3.6 5.5 6.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RasGAP_C PF03836.10 OAJ25943.1 - 4.2 7.0 8.8 4.1 7.0 0.9 2.1 2 0 0 2 2 2 0 RasGAP C-terminus Ribosomal_L21p PF00829.16 OAJ25944.1 - 2.6e-08 33.8 1.4 1e-06 28.7 1.5 2.1 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein Nucleoside_tran PF01733.13 OAJ25945.1 - 3.3e-21 75.7 9.5 9.1e-19 67.7 2.7 3.6 2 1 1 3 3 3 2 Nucleoside transporter Pkinase PF00069.20 OAJ25946.1 - 5.1e-23 81.5 0.0 6e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ25946.1 - 7.4e-14 51.4 0.0 1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ25946.1 - 0.00015 20.8 0.0 0.0002 20.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ25946.1 - 0.073 12.7 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Reo_sigmaC PF04582.7 OAJ25947.1 - 0.03 13.4 5.1 1.2 8.1 1.5 2.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 OAJ25947.1 - 0.37 10.5 38.3 0.58 9.9 5.6 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF869 PF05911.6 OAJ25947.1 - 1.3 7.2 35.1 0.092 10.9 17.1 2.9 2 1 0 2 2 2 0 Plant protein of unknown function (DUF869) FUSC PF04632.7 OAJ25947.1 - 1.7 6.9 12.7 0.45 8.8 5.8 2.1 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF4061 PF13270.1 OAJ25948.1 - 0.46 10.5 4.7 5.7 7.1 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Longin PF13774.1 OAJ25949.1 - 3.2e-23 81.0 0.0 5.7e-23 80.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 OAJ25949.1 - 4e-14 51.9 0.1 8.5e-14 50.9 0.1 1.6 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 OAJ25949.1 - 0.043 13.6 0.2 0.068 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FliJ PF02050.11 OAJ25949.1 - 0.5 10.4 4.1 0.13 12.3 0.7 1.6 2 0 0 2 2 2 0 Flagellar FliJ protein PRANC PF09372.5 OAJ25951.1 - 0.32 10.9 0.0 0.57 10.1 0.0 1.3 1 0 0 1 1 1 0 PRANC domain Glyco_hydro_63 PF03200.11 OAJ25952.1 - 8.7e-231 768.0 0.0 7.7e-230 764.9 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 OAJ25952.1 - 3.6e-05 22.5 0.0 5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Trehalase HLH PF00010.21 OAJ25954.1 - 3.4e-07 29.8 0.0 1e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Suf PF05843.9 OAJ25954.1 - 0.24 11.0 20.9 1.3 8.6 5.8 2.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PBP1_TM PF14812.1 OAJ25954.1 - 2.1 8.6 6.3 1.3 9.4 0.2 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Citrate_synt PF00285.16 OAJ25955.1 - 1.6e-95 319.9 0.0 1.9e-95 319.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 OAJ25955.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone OPT PF03169.10 OAJ25956.1 - 7.8e-135 450.7 2.4 1e-134 450.3 1.7 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4432 PF14486.1 OAJ25957.1 - 0.071 11.6 0.0 0.097 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) F-box-like PF12937.2 OAJ25957.1 - 0.084 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like AAA_2 PF07724.9 OAJ25958.1 - 2.7e-31 108.7 0.0 1.1e-23 84.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 OAJ25958.1 - 1.6e-12 47.7 0.0 3.5e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 OAJ25958.1 - 2e-11 43.6 0.0 4.4e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 OAJ25958.1 - 5.5e-05 23.2 0.6 0.00014 21.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain MCM PF00493.18 OAJ25958.1 - 7.4e-05 21.7 0.1 0.0002 20.2 0.0 1.7 2 0 0 2 2 2 1 MCM2/3/5 family AAA_5 PF07728.9 OAJ25958.1 - 8.9e-05 22.2 0.0 0.00027 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 OAJ25958.1 - 0.0001 22.4 0.1 0.00044 20.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ25958.1 - 0.00089 20.0 0.0 0.0028 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 OAJ25958.1 - 0.0084 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAJ25958.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 OAJ25958.1 - 0.024 14.5 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAJ25958.1 - 0.027 14.1 0.0 0.079 12.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 OAJ25958.1 - 0.058 12.8 0.1 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 OAJ25958.1 - 0.075 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 OAJ25958.1 - 0.089 11.9 1.3 0.58 9.2 0.0 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 OAJ25958.1 - 0.096 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 OAJ25958.1 - 0.13 12.5 0.1 0.35 11.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain DNA_ligase_A_C PF04679.10 OAJ25959.1 - 3e-20 72.4 0.0 3.7e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 OAJ25959.1 - 0.023 14.3 0.2 2.5 7.8 0.1 2.2 2 0 0 2 2 2 0 DNA ligase OB-like domain DNA_ligase_A_M PF01068.16 OAJ25960.1 - 1.8e-58 197.2 0.1 3.5e-58 196.3 0.1 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 OAJ25960.1 - 1.7e-53 181.0 0.1 2.9e-53 180.2 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus Synaptonemal_3 PF15191.1 OAJ25960.1 - 0.067 12.9 0.0 1.4 8.7 0.0 2.9 2 1 0 2 2 2 0 Synaptonemal complex central element protein 3 SMC_N PF02463.14 OAJ25961.1 - 9.4e-70 234.2 0.0 7.1e-68 228.1 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 OAJ25961.1 - 5.4e-20 71.5 0.7 3.3e-19 69.0 0.1 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 OAJ25961.1 - 2.7e-16 60.5 12.6 2.7e-16 60.5 8.8 6.3 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 OAJ25961.1 - 5.7e-14 52.7 8.6 1.4e-06 28.4 0.0 3.4 4 0 0 4 4 4 2 AAA domain WEMBL PF05701.6 OAJ25961.1 - 3.3e-06 25.8 44.0 3.3e-06 25.8 30.5 4.1 3 1 1 4 4 4 1 Weak chloroplast movement under blue light AAA_29 PF13555.1 OAJ25961.1 - 2.1e-05 23.9 0.1 6.2e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain FliJ PF02050.11 OAJ25961.1 - 0.0048 16.9 13.4 0.0048 16.9 9.3 9.0 5 3 4 10 10 10 1 Flagellar FliJ protein XhlA PF10779.4 OAJ25961.1 - 0.0064 16.3 3.7 0.0064 16.3 2.6 8.3 10 2 0 11 11 11 2 Haemolysin XhlA Reo_sigmaC PF04582.7 OAJ25961.1 - 0.22 10.6 28.6 0.35 10.0 1.1 5.5 4 1 2 6 6 6 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 OAJ25961.1 - 0.26 11.5 0.0 0.26 11.5 0.0 6.3 3 2 0 3 3 3 0 ABC transporter CPSase_L_D2 PF02786.12 OAJ25962.1 - 6.6e-114 378.4 0.1 3.4e-82 274.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 OAJ25962.1 - 9.6e-45 151.2 0.0 2e-44 150.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 OAJ25962.1 - 8.9e-43 145.3 0.0 1.7e-42 144.4 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 OAJ25962.1 - 9.1e-42 141.6 0.0 2.4e-21 75.8 0.0 3.0 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain GATase PF00117.23 OAJ25962.1 - 9.4e-42 142.6 0.0 2.4e-41 141.3 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.14 OAJ25962.1 - 4.7e-40 136.1 0.0 1e-39 135.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.19 OAJ25962.1 - 4.8e-36 124.0 0.0 9.9e-36 122.9 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 OAJ25962.1 - 2.9e-35 121.6 0.2 2.1e-20 73.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAJ25962.1 - 1.3e-20 73.4 0.0 3.7e-12 45.6 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 OAJ25962.1 - 1.1e-15 57.3 0.0 5.6e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 OAJ25962.1 - 1.6e-15 57.0 0.1 6.1e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.17 OAJ25962.1 - 8.5e-12 44.8 0.0 3e-11 43.0 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain Peptidase_C26 PF07722.8 OAJ25962.1 - 1.4e-05 24.6 0.0 0.0004 19.9 0.0 2.6 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 OAJ25962.1 - 5e-05 23.2 0.1 0.34 10.7 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 OAJ25962.1 - 0.0057 16.2 0.0 0.29 10.6 0.0 2.8 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 OAJ25962.1 - 0.0086 15.5 0.0 0.91 8.9 0.0 2.4 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Peptidase_C71 PF12386.3 OAJ25962.1 - 0.21 10.9 0.0 0.61 9.5 0.0 1.7 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei Glyoxalase_3 PF13468.1 OAJ25963.1 - 9e-24 84.3 3.5 3.2e-14 53.2 0.0 3.6 4 0 0 4 4 4 3 Glyoxalase-like domain zf-CCHC_6 PF15288.1 OAJ25964.1 - 0.0047 16.5 0.4 0.012 15.2 0.3 1.7 1 0 0 1 1 1 1 Zinc knuckle DPBB_1 PF03330.13 OAJ25965.1 - 8.5e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ25965.1 - 0.0011 18.6 0.0 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 Barwin family Sybindin PF04099.7 OAJ25966.1 - 1.2e-39 135.2 0.0 1.3e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 OAJ25966.1 - 1.5e-07 31.3 0.0 1.5e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region PilP PF04351.8 OAJ25966.1 - 0.15 11.9 0.0 0.44 10.4 0.0 1.8 1 1 1 2 2 2 0 Pilus assembly protein, PilP TIG PF01833.19 OAJ25967.1 - 2.9e-12 46.4 1.3 2.3e-11 43.5 1.2 2.3 2 0 0 2 2 2 1 IPT/TIG domain Ank PF00023.25 OAJ25967.1 - 9e-12 44.1 2.2 1.9e-05 24.2 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 OAJ25967.1 - 4.5e-11 42.6 0.6 4.6e-10 39.4 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 OAJ25967.1 - 6.2e-11 42.4 0.0 1.3e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ25967.1 - 5.7e-09 36.2 1.7 1.2e-08 35.2 1.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ25967.1 - 0.00011 22.0 0.9 0.029 14.5 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Adaptin_N PF01602.15 OAJ25974.1 - 3.1e-139 464.6 2.0 3.9e-139 464.3 1.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 OAJ25974.1 - 1e-25 90.5 1.9 6.9e-24 84.6 0.1 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 OAJ25974.1 - 2.3e-16 59.8 8.6 1.8e-09 37.7 0.1 4.9 1 1 3 5 5 5 3 HEAT repeats HEAT PF02985.17 OAJ25974.1 - 3.1e-09 36.1 4.4 0.0047 16.8 0.0 5.4 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.18 OAJ25974.1 - 1.7e-06 27.5 3.2 0.0051 16.5 0.0 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 OAJ25974.1 - 6.6e-05 23.2 6.9 0.52 10.8 0.1 5.8 6 1 1 7 7 7 2 HEAT-like repeat Cnd3 PF12719.2 OAJ25974.1 - 9.2e-05 21.5 0.0 0.0076 15.2 0.0 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Arm_2 PF04826.8 OAJ25974.1 - 0.0011 18.1 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 Armadillo-like Atx10homo_assoc PF09759.4 OAJ25974.1 - 0.099 12.3 0.0 3.1 7.5 0.0 3.0 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 OAJ25974.1 - 0.19 11.0 4.4 5.7 6.2 0.0 3.5 4 1 1 5 5 5 0 CLASP N terminal DUF4202 PF13875.1 OAJ25975.1 - 1.7e-54 184.2 0.0 2.9e-54 183.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Methyltransf_12 PF08242.7 OAJ25975.1 - 1.1e-14 54.7 0.0 1e-12 48.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ25975.1 - 8.3e-14 51.6 0.0 2.1e-12 47.0 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ25975.1 - 7.7e-09 35.9 0.0 7e-07 29.6 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ25975.1 - 3.4e-08 33.7 0.0 1.1e-07 32.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ25975.1 - 3.8e-08 33.0 0.0 1.6e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ25975.1 - 6.3e-07 29.9 0.0 2.4e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 OAJ25975.1 - 0.00048 19.5 0.0 0.00084 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 OAJ25975.1 - 0.0035 17.3 0.0 0.014 15.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 OAJ25975.1 - 0.0043 17.8 0.0 0.027 15.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain NAM-associated PF14303.1 OAJ25976.1 - 0.21 11.9 18.6 0.025 14.8 9.4 1.9 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Nucleoplasmin PF03066.10 OAJ25976.1 - 8.7 5.8 11.4 0.11 11.9 2.7 1.7 2 0 0 2 2 2 0 Nucleoplasmin TFIID-18kDa PF02269.11 OAJ25977.1 - 6.3e-32 109.2 0.5 1.7e-30 104.6 0.5 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Proteasome PF00227.21 OAJ25978.1 - 1.7e-31 108.9 0.0 2.1e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HAMP PF00672.20 OAJ25979.1 - 8.2e-46 154.0 19.6 1.1e-07 31.8 0.1 8.0 7 0 0 7 7 7 7 HAMP domain Response_reg PF00072.19 OAJ25979.1 - 5.5e-27 93.9 0.7 1.2e-24 86.4 0.3 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 OAJ25979.1 - 5.9e-27 93.5 0.0 2e-26 91.8 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 OAJ25979.1 - 6e-17 61.3 0.3 4.7e-16 58.5 0.2 2.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pox_A_type_inc PF04508.7 OAJ25979.1 - 0.067 13.0 0.2 0.97 9.3 0.0 3.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PMC2NT PF08066.7 OAJ25979.1 - 0.36 11.1 5.3 3.7 7.9 0.0 4.2 4 0 0 4 4 4 0 PMC2NT (NUC016) domain Syntaxin PF00804.20 OAJ25979.1 - 1.7 8.8 6.7 16 5.7 1.2 4.5 3 2 0 3 3 3 0 Syntaxin MFS_1 PF07690.11 OAJ25980.1 - 3.9e-06 25.8 2.0 5e-06 25.4 1.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DDE_Tnp_4 PF13359.1 OAJ25981.1 - 1.8e-17 63.4 0.0 3.3e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease RyR PF02026.11 OAJ25981.1 - 0.0018 18.2 0.8 0.0089 16.0 0.2 2.4 2 0 0 2 2 2 1 RyR domain Toprim_C_rpt PF13368.1 OAJ25981.1 - 0.14 12.6 0.0 0.46 11.0 0.0 1.9 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat Fumble PF03630.9 OAJ25982.1 - 1.3e-108 362.9 0.0 2.3e-82 276.5 0.0 3.2 3 0 0 3 3 3 3 Fumble TFIIA PF03153.8 OAJ25982.1 - 0.9 9.3 6.4 2.2 8.0 4.4 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.8 OAJ25982.1 - 5.9 4.5 6.8 8 4.0 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi B-block_TFIIIC PF04182.7 OAJ25983.1 - 7e-07 29.0 0.0 2.1e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC PNGaseA PF12222.3 OAJ25984.1 - 5.6e-60 203.3 0.3 1.6e-40 139.2 0.1 2.1 2 0 0 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Saccharop_dh PF03435.13 OAJ25986.1 - 1.1e-104 350.4 0.0 1.8e-104 349.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 OAJ25986.1 - 3.2e-85 284.9 0.0 5.7e-85 284.1 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase Semialdhyde_dh PF01118.19 OAJ25986.1 - 0.00029 21.1 0.2 0.0011 19.2 0.1 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 OAJ25986.1 - 0.00096 19.2 0.3 0.0035 17.3 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding SQS_PSY PF00494.14 OAJ25987.1 - 2e-49 168.2 0.9 5.6e-49 166.8 0.6 1.8 1 1 0 1 1 1 1 Squalene/phytoene synthase MFS_1 PF07690.11 OAJ25988.1 - 4.3e-77 259.2 110.5 2e-39 135.3 35.9 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 OAJ25988.1 - 4.7e-21 74.6 57.1 2e-11 42.8 16.6 2.1 1 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 OAJ25988.1 - 7.1e-17 61.1 31.3 6.3e-10 38.2 6.6 5.4 3 2 2 6 6 6 3 Sugar (and other) transporter UCR_UQCRX_QCR9 PF05365.7 OAJ25988.1 - 0.083 12.5 0.8 8.3 6.1 0.1 3.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like MRAP PF15183.1 OAJ25988.1 - 0.1 12.1 0.8 7.6 6.2 0.0 3.0 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Glycoprotein PF03409.10 OAJ25988.1 - 0.21 10.2 0.8 12 4.5 0.0 2.1 2 0 0 2 2 2 0 Transmembrane glycoprotein HCV_NS4a PF01006.15 OAJ25988.1 - 0.8 9.2 12.9 2.2 7.9 1.2 3.4 3 0 0 3 3 3 0 Hepatitis C virus non-structural protein NS4a Dak2 PF02734.12 OAJ25988.1 - 3.3 7.3 6.6 26 4.4 0.3 3.6 4 0 0 4 4 4 0 DAK2 domain DUF2422 PF10337.4 OAJ25989.1 - 9.3e-91 304.9 0.1 1.8e-88 297.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 OAJ25989.1 - 7.1e-27 94.5 0.0 2.3e-26 92.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 OAJ25989.1 - 3e-08 33.6 18.6 3e-08 33.6 12.9 3.7 2 1 1 3 3 3 1 Fusaric acid resistance protein-like DUF1180 PF06679.7 OAJ25989.1 - 0.009 15.9 3.6 1.6 8.6 0.0 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1180) Retinal PF15449.1 OAJ25990.1 - 0.011 13.4 5.5 0.016 12.9 3.8 1.1 1 0 0 1 1 1 0 Retinal protein 4HBT PF03061.17 OAJ25991.1 - 2.7e-17 62.6 1.7 1.2e-11 44.5 0.1 3.0 3 1 1 4 4 4 2 Thioesterase superfamily Mito_fiss_reg PF05308.6 OAJ25991.1 - 0.084 12.2 5.0 0.2 11.0 3.5 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator WES_acyltransf PF03007.11 OAJ25992.1 - 4.2e-16 59.3 0.7 8e-16 58.3 0.0 1.8 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain SH3_9 PF14604.1 OAJ25994.1 - 1.5e-08 34.0 0.0 2.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ25994.1 - 6.9e-08 31.7 0.0 1.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ25994.1 - 0.00052 19.4 0.1 0.0014 18.0 0.0 1.7 1 1 0 1 1 1 1 Variant SH3 domain ASF1_hist_chap PF04729.8 OAJ25996.1 - 8.1e-57 191.1 1.2 9.5e-56 187.7 0.8 1.9 1 1 0 1 1 1 1 ASF1 like histone chaperone NmrA PF05368.8 OAJ25997.1 - 1.9e-25 89.5 0.0 2.5e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAJ25997.1 - 4.5e-12 46.3 0.0 3.6e-11 43.4 0.0 2.0 1 1 1 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 OAJ25997.1 - 9e-07 28.1 0.0 1.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 OAJ25997.1 - 0.0018 18.2 0.0 0.0067 16.4 0.0 2.0 3 0 0 3 3 3 1 TrkA-N domain Shikimate_DH PF01488.15 OAJ25997.1 - 0.0077 16.3 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 OAJ25997.1 - 0.025 14.4 0.1 0.06 13.1 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 OAJ25997.1 - 0.17 12.3 1.1 0.38 11.2 0.0 2.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent IGPS PF00218.16 OAJ25998.1 - 2.4e-85 285.6 0.0 1.3e-84 283.2 0.0 2.2 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 OAJ25998.1 - 5.3e-45 153.2 0.0 1e-44 152.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.17 OAJ25998.1 - 1.8e-39 135.3 0.0 4.6e-35 120.9 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 OAJ25998.1 - 1.3e-06 27.9 0.1 3e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 Peptidase C26 OPA3 PF07047.7 OAJ26000.1 - 7.2e-36 122.9 0.8 1.5e-35 121.9 0.5 1.5 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF2763 PF10961.3 OAJ26000.1 - 5.3 7.5 12.0 13 6.3 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) Histone_HNS PF00816.16 OAJ26000.1 - 8.6 6.9 8.0 1.9 9.0 1.2 2.3 2 0 0 2 2 2 0 H-NS histone family Pyr_redox_dim PF02852.17 OAJ26001.1 - 1e-40 138.2 0.1 2.5e-40 136.9 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 OAJ26001.1 - 1.6e-38 132.6 19.3 5.8e-28 98.1 5.0 3.8 2 1 2 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ26001.1 - 5.5e-22 77.9 11.2 3.5e-19 68.9 1.6 3.7 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAJ26001.1 - 8.9e-12 44.8 0.2 8.9e-12 44.8 0.1 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAJ26001.1 - 9e-12 45.4 0.9 4.9e-07 30.0 0.2 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAJ26001.1 - 1.8e-09 37.4 4.8 5.8e-05 23.0 0.3 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 OAJ26001.1 - 1.5e-07 30.6 15.1 2.5e-07 29.9 3.8 3.0 2 2 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 OAJ26001.1 - 1.5e-07 30.6 2.5 1.5e-07 30.6 1.7 3.6 3 1 0 4 4 4 1 FAD binding domain K_oxygenase PF13434.1 OAJ26001.1 - 5.3e-07 28.8 0.9 0.032 13.1 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 OAJ26001.1 - 3e-06 26.4 7.0 6.8e-06 25.3 0.1 2.6 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.9 OAJ26001.1 - 3.2e-06 25.8 14.3 0.00014 20.5 0.8 4.0 3 1 1 4 4 4 2 HI0933-like protein DAO PF01266.19 OAJ26001.1 - 8.4e-05 21.6 18.6 0.0027 16.6 0.4 3.7 3 1 1 4 4 4 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 OAJ26001.1 - 0.00017 21.1 4.0 0.0019 17.7 0.3 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 OAJ26001.1 - 0.00044 19.4 12.3 0.014 14.4 0.8 3.4 3 1 0 3 3 3 2 FAD binding domain THF_DHG_CYH_C PF02882.14 OAJ26001.1 - 0.033 13.2 0.4 0.11 11.5 0.1 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.7 OAJ26001.1 - 0.13 11.1 2.9 0.16 10.8 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 OAJ26001.1 - 7.4 6.8 6.9 25 5.2 0.8 3.0 3 1 0 3 3 3 0 Putative NAD(P)-binding adh_short_C2 PF13561.1 OAJ26002.1 - 7.3e-33 114.3 0.1 9.2e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ26002.1 - 6.1e-29 101.0 0.3 7.8e-29 100.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ26002.1 - 2.8e-11 43.3 0.1 4.2e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAJ26002.1 - 0.00014 21.4 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 OAJ26002.1 - 0.0093 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 OAJ26002.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF1620 PF07774.8 OAJ26003.1 - 2.6e-58 196.8 0.0 4.3e-58 196.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 OAJ26003.1 - 3.3e-11 43.1 7.6 5.3e-05 22.7 0.0 4.0 4 0 0 4 4 4 2 PQQ-like domain PQQ PF01011.16 OAJ26003.1 - 2.7e-09 36.1 0.2 0.0029 17.0 0.0 4.3 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_3 PF13570.1 OAJ26003.1 - 0.23 11.7 4.4 15 5.9 0.0 5.5 6 0 0 6 6 6 0 PQQ-like domain Cutinase PF01083.17 OAJ26013.1 - 3.3e-21 75.8 0.0 4.2e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Cutinase Cutinase PF01083.17 OAJ26014.1 - 8.6e-27 94.0 0.1 1.1e-26 93.7 0.1 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ26014.1 - 0.002 17.7 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 OAJ26014.1 - 0.044 13.2 0.1 0.15 11.4 0.0 1.7 1 1 1 2 2 2 0 Serine hydrolase (FSH1) PE-PPE PF08237.6 OAJ26014.1 - 0.093 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Ribosomal_S27e PF01667.12 OAJ26015.1 - 1.7e-29 101.1 2.4 2.1e-29 100.8 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-CSL PF05207.8 OAJ26015.1 - 0.028 13.9 0.5 0.052 13.0 0.3 1.4 1 0 0 1 1 1 0 CSL zinc finger RIX1 PF08167.7 OAJ26015.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis DUF3133 PF11331.3 OAJ26015.1 - 0.14 11.7 4.9 0.5 9.9 2.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) Ribosomal_S27e PF01667.12 OAJ26016.1 - 1.7e-29 101.1 2.4 2.1e-29 100.8 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-CSL PF05207.8 OAJ26016.1 - 0.028 13.9 0.5 0.052 13.0 0.3 1.4 1 0 0 1 1 1 0 CSL zinc finger RIX1 PF08167.7 OAJ26016.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis DUF3133 PF11331.3 OAJ26016.1 - 0.14 11.7 4.9 0.5 9.9 2.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) DUF2413 PF10310.4 OAJ26017.1 - 3.1e-54 184.4 4.7 5.2e-53 180.4 3.3 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) Pardaxin PF07425.6 OAJ26017.1 - 0.057 12.8 1.0 0.18 11.2 0.7 1.8 1 0 0 1 1 1 0 Pardaxin DUF3439 PF11921.3 OAJ26017.1 - 4.1 7.1 10.8 10 5.9 7.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Hist_deacetyl PF00850.14 OAJ26019.1 - 5.3e-81 272.2 0.0 7.6e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ATP-synt_F PF01990.12 OAJ26020.1 - 3.9e-27 94.4 0.1 4.4e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit AA_permease_2 PF13520.1 OAJ26021.1 - 1e-81 274.6 39.2 1.2e-81 274.4 27.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAJ26021.1 - 3.1e-19 68.6 33.0 7.1e-19 67.4 22.9 1.5 1 1 0 1 1 1 1 Amino acid permease Ribosomal_L19e PF01280.15 OAJ26022.1 - 6.2e-59 198.0 12.4 6.2e-59 198.0 8.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e S4 PF01479.20 OAJ26022.1 - 0.0029 16.9 0.2 0.01 15.2 0.1 1.9 1 0 0 1 1 1 1 S4 domain Adeno_E4_34 PF04528.8 OAJ26022.1 - 2.4 7.7 5.5 18 4.8 0.1 2.3 2 0 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region CBS PF00571.23 OAJ26023.1 - 1.4e-34 117.5 8.9 5.7e-09 35.6 0.0 5.2 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 OAJ26023.1 - 2.3e-06 27.1 0.1 2.1e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 PB1 domain Glyco_hydro_88 PF07470.8 OAJ26024.1 - 1.3e-14 54.0 1.0 2.7e-14 52.9 0.5 1.6 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Zn_clus PF00172.13 OAJ26025.1 - 5.9e-08 32.4 28.1 6e-06 26.0 5.9 3.3 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4051 PF13260.1 OAJ26025.1 - 0.21 10.9 0.1 0.44 9.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Ribonuc_L-PSP PF01042.16 OAJ26026.1 - 3.1e-41 139.9 0.1 3.6e-41 139.7 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP ATP-synt_DE PF00401.15 OAJ26027.1 - 0.03 14.1 1.8 0.048 13.5 1.2 1.3 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain SR-25 PF10500.4 OAJ26027.1 - 0.66 9.3 3.7 0.19 11.1 0.4 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ATP12 PF07542.6 OAJ26028.1 - 2.4e-36 124.3 0.0 4.2e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Pox_P4B PF03292.9 OAJ26030.1 - 0.44 8.4 0.2 0.65 7.8 0.1 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein Clathrin PF00637.15 OAJ26031.1 - 2.1e-164 539.6 27.0 3.9e-31 107.5 0.7 8.1 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 OAJ26031.1 - 1.2e-30 105.1 0.1 5e-30 103.1 0.1 2.2 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 OAJ26031.1 - 8.5e-29 97.8 7.1 0.00032 20.8 0.0 7.4 7 0 0 7 7 7 6 Clathrin propeller repeat Coatomer_WDAD PF04053.9 OAJ26031.1 - 3.7e-05 22.7 7.3 1.4 7.6 0.0 4.8 5 0 0 5 5 5 3 Coatomer WD associated region TPR_7 PF13176.1 OAJ26031.1 - 0.0044 16.7 8.5 31 4.7 0.0 6.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ26031.1 - 0.0097 15.6 0.5 38 4.3 0.0 4.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ26031.1 - 0.017 14.9 14.8 5.8 7.0 0.1 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ26031.1 - 0.12 12.6 2.6 29 5.1 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ26031.1 - 0.13 11.9 10.5 4.7 6.9 0.1 5.4 5 1 0 5 5 5 0 TPR repeat TPR_12 PF13424.1 OAJ26031.1 - 0.15 12.0 15.0 26 4.8 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ26031.1 - 0.29 10.8 14.7 9 6.0 0.1 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ26031.1 - 0.41 11.4 18.3 48 4.9 0.1 9.6 10 2 2 12 12 11 0 Tetratricopeptide repeat AAA PF00004.24 OAJ26032.1 - 5.8e-43 146.2 0.0 9.6e-43 145.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAJ26032.1 - 2.5e-07 30.5 0.1 3.4e-06 26.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 OAJ26032.1 - 5.5e-07 29.7 0.1 3e-05 24.0 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 OAJ26032.1 - 1.3e-06 28.4 0.0 9.4e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 OAJ26032.1 - 2.8e-06 27.4 0.1 0.0012 19.0 0.0 2.7 2 1 1 3 3 2 1 AAA domain RuvB_N PF05496.7 OAJ26032.1 - 1.1e-05 24.5 0.0 2.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 OAJ26032.1 - 6.1e-05 22.7 0.1 0.0002 21.0 0.1 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_17 PF13207.1 OAJ26032.1 - 0.00032 21.4 0.9 0.0012 19.6 0.2 2.4 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 OAJ26032.1 - 0.00093 18.1 0.0 0.0019 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 OAJ26032.1 - 0.0023 17.8 0.0 0.0054 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 OAJ26032.1 - 0.0029 16.7 0.0 0.006 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 OAJ26032.1 - 0.0033 16.8 0.0 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 OAJ26032.1 - 0.0034 16.1 0.0 0.0059 15.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 OAJ26032.1 - 0.0037 17.1 0.0 0.0077 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ26032.1 - 0.0042 17.3 0.2 0.022 15.0 0.0 2.3 2 1 0 3 3 2 1 AAA domain DUF4200 PF13863.1 OAJ26032.1 - 0.0063 16.4 0.3 0.0063 16.4 0.2 1.7 2 0 0 2 2 1 1 Domain of unknown function (DUF4200) AAA_28 PF13521.1 OAJ26032.1 - 0.0071 16.3 0.1 0.021 14.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 OAJ26032.1 - 0.0078 15.6 0.2 0.041 13.2 0.1 2.1 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.21 OAJ26032.1 - 0.0087 15.5 0.0 0.032 13.6 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 OAJ26032.1 - 0.0089 15.1 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 OAJ26032.1 - 0.0098 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 OAJ26032.1 - 0.011 15.3 0.1 0.028 14.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 OAJ26032.1 - 0.011 15.5 0.0 0.039 13.7 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 OAJ26032.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 OAJ26032.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.1 OAJ26032.1 - 0.032 13.8 0.4 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 OAJ26032.1 - 0.042 12.9 0.1 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 KaiC UPF0079 PF02367.12 OAJ26032.1 - 0.044 13.4 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 OAJ26032.1 - 0.051 12.4 0.0 0.084 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 OAJ26032.1 - 0.072 12.7 0.0 0.37 10.4 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase NACHT PF05729.7 OAJ26032.1 - 0.073 12.7 0.0 0.21 11.2 0.0 1.8 1 1 1 2 2 2 0 NACHT domain CPT PF07931.7 OAJ26032.1 - 0.089 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.1 OAJ26032.1 - 0.11 12.8 3.7 4.2 7.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain Complex1_LYR_1 PF13232.1 OAJ26033.1 - 1.6e-09 37.8 4.1 2.5e-09 37.1 2.8 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 OAJ26033.1 - 5.1e-09 35.8 5.5 9.7e-09 34.8 3.8 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 OAJ26033.1 - 0.026 15.0 0.6 0.041 14.3 0.4 1.3 1 0 0 1 1 1 0 Complex1_LYR-like CAF-1_p150 PF11600.3 OAJ26034.1 - 0.0013 18.1 16.9 0.0018 17.6 11.7 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1649 PF07855.7 OAJ26034.1 - 0.049 13.3 1.8 0.085 12.5 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1649) Herpes_UL25 PF01499.11 OAJ26034.1 - 0.059 11.6 0.3 0.075 11.3 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family CcmH PF03918.9 OAJ26034.1 - 0.061 12.3 0.0 0.17 10.8 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Cutinase PF01083.17 OAJ26036.1 - 8e-29 100.6 0.0 9.8e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 OAJ26036.1 - 0.00078 18.9 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Lipase_3 PF01764.20 OAJ26036.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.15 OAJ26036.1 - 0.016 14.7 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold ECR1_N PF14382.1 OAJ26036.1 - 0.02 14.1 0.0 0.057 12.7 0.0 1.8 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region Abhydrolase_8 PF06259.7 OAJ26036.1 - 0.037 13.5 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase LIP PF03583.9 OAJ26036.1 - 0.06 12.5 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase Acetyltransf_1 PF00583.19 OAJ26037.1 - 4.5e-14 52.2 0.0 7.1e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAJ26037.1 - 0.00017 21.7 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAJ26037.1 - 0.00017 21.7 0.0 0.00034 20.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ26037.1 - 0.0024 17.5 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 OAJ26037.1 - 0.12 12.1 0.1 0.26 11.1 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ubiquitin PF00240.18 OAJ26038.1 - 1.3e-102 335.2 16.4 6.6e-34 115.1 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 OAJ26038.1 - 6.7e-59 195.5 15.0 3.3e-19 68.3 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAJ26038.1 - 1.1e-18 67.2 7.1 9.6e-05 22.5 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAJ26038.1 - 2.7e-16 59.6 0.5 0.00062 19.4 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing DUF2407 PF10302.4 OAJ26038.1 - 9e-11 41.8 0.8 0.066 13.4 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 OAJ26038.1 - 9.7e-11 41.5 1.5 0.081 12.8 0.0 3.8 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 OAJ26038.1 - 7e-08 32.4 0.0 1 9.4 0.0 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 OAJ26038.1 - 5.7e-05 22.7 2.5 4.5 7.0 0.0 3.3 3 0 0 3 3 3 3 FlgD Ig-like domain TUG-UBL1 PF11470.3 OAJ26038.1 - 0.00017 21.4 3.3 4.8 7.1 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF3221 PF11518.3 OAJ26038.1 - 0.00021 20.9 0.8 8.5 6.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3221) Methyltrans_RNA PF04452.9 OAJ26038.1 - 0.00038 19.6 0.2 0.83 8.7 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase IGR PF09597.5 OAJ26038.1 - 0.00041 20.1 0.1 16 5.4 0.0 3.3 3 0 0 3 3 3 0 IGR protein motif Big_3_3 PF13750.1 OAJ26038.1 - 0.00059 19.2 0.0 12 5.2 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 OAJ26038.1 - 0.0048 15.2 8.7 2.4 6.3 0.2 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain USP7_C2 PF14533.1 OAJ26038.1 - 0.0076 15.6 2.2 14 5.0 0.0 3.0 1 1 1 3 3 3 0 Ubiquitin-specific protease C-terminal ACT_4 PF13291.1 OAJ26038.1 - 0.023 15.0 0.4 72 3.8 0.0 3.2 3 0 0 3 3 3 0 ACT domain DUF3861 PF12977.2 OAJ26038.1 - 0.027 14.5 3.2 34 4.6 0.0 3.4 1 1 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) Tash_PEST PF07708.6 OAJ26038.1 - 0.036 13.9 19.8 2.5 8.1 1.2 3.4 3 0 0 3 3 3 0 Tash protein PEST motif GABP-alpha PF11620.3 OAJ26038.1 - 0.041 13.8 3.9 28 4.7 0.1 3.1 3 0 0 3 3 3 0 GA-binding protein alpha chain EMG1 PF03587.9 OAJ26038.1 - 0.059 12.6 0.9 16 4.6 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase CTDII PF01556.13 OAJ26038.1 - 0.067 13.0 10.9 4.1 7.3 0.3 3.5 1 1 2 3 3 3 0 DnaJ C terminal domain Sortase PF04203.8 OAJ26038.1 - 0.14 11.7 1.6 23 4.5 0.0 3.0 1 1 2 3 3 3 0 Sortase family FERM_N PF09379.5 OAJ26038.1 - 0.39 10.8 9.5 37 4.4 0.2 4.7 3 3 0 3 3 3 0 FERM N-terminal domain DUF3781 PF12636.2 OAJ26038.1 - 0.55 10.2 3.9 82 3.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) FHA PF00498.21 OAJ26040.1 - 1.1e-14 54.3 0.1 1.9e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 OAJ26040.1 - 6.8e-08 32.2 13.9 1e-07 31.6 9.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAJ26040.1 - 0.00033 20.6 7.0 0.00057 19.9 4.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 OAJ26040.1 - 0.02 14.7 5.2 0.033 14.0 3.6 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 OAJ26040.1 - 0.037 13.7 13.0 0.056 13.1 9.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ26040.1 - 0.1 12.3 11.9 0.17 11.6 8.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Daxx PF03344.10 OAJ26040.1 - 0.73 8.2 10.2 1.3 7.3 7.1 1.3 1 0 0 1 1 1 0 Daxx Family PHD PF00628.24 OAJ26040.1 - 0.76 9.5 7.8 1.4 8.6 5.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.1 OAJ26040.1 - 0.86 9.6 15.3 1.3 9.0 10.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CDC45 PF02724.9 OAJ26040.1 - 1.1 7.1 7.3 1.6 6.6 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Aida_N PF08910.5 OAJ26041.1 - 6.3 7.0 12.4 0.04 14.1 1.4 2.6 3 0 0 3 3 3 0 Aida N-terminus Sec1 PF00995.18 OAJ26042.1 - 2.2e-132 442.6 0.0 3.1e-132 442.0 0.0 1.2 1 0 0 1 1 1 1 Sec1 family ubiquitin PF00240.18 OAJ26043.1 - 1.3e-102 335.2 16.4 6.6e-34 115.1 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 OAJ26043.1 - 6.7e-59 195.5 15.0 3.3e-19 68.3 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAJ26043.1 - 1.1e-18 67.2 7.1 9.6e-05 22.5 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAJ26043.1 - 2.7e-16 59.6 0.5 0.00062 19.4 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing DUF2407 PF10302.4 OAJ26043.1 - 9e-11 41.8 0.8 0.066 13.4 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 OAJ26043.1 - 9.7e-11 41.5 1.5 0.081 12.8 0.0 3.8 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 OAJ26043.1 - 7e-08 32.4 0.0 1 9.4 0.0 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 OAJ26043.1 - 5.7e-05 22.7 2.5 4.5 7.0 0.0 3.3 3 0 0 3 3 3 3 FlgD Ig-like domain TUG-UBL1 PF11470.3 OAJ26043.1 - 0.00017 21.4 3.3 4.8 7.1 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF3221 PF11518.3 OAJ26043.1 - 0.00021 20.9 0.8 8.5 6.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3221) Methyltrans_RNA PF04452.9 OAJ26043.1 - 0.00038 19.6 0.2 0.83 8.7 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase IGR PF09597.5 OAJ26043.1 - 0.00041 20.1 0.1 16 5.4 0.0 3.3 3 0 0 3 3 3 0 IGR protein motif Big_3_3 PF13750.1 OAJ26043.1 - 0.00059 19.2 0.0 12 5.2 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 OAJ26043.1 - 0.0048 15.2 8.7 2.4 6.3 0.2 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain USP7_C2 PF14533.1 OAJ26043.1 - 0.0076 15.6 2.2 14 5.0 0.0 3.0 1 1 1 3 3 3 0 Ubiquitin-specific protease C-terminal ACT_4 PF13291.1 OAJ26043.1 - 0.023 15.0 0.4 72 3.8 0.0 3.2 3 0 0 3 3 3 0 ACT domain DUF3861 PF12977.2 OAJ26043.1 - 0.027 14.5 3.2 34 4.6 0.0 3.4 1 1 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) Tash_PEST PF07708.6 OAJ26043.1 - 0.036 13.9 19.8 2.5 8.1 1.2 3.4 3 0 0 3 3 3 0 Tash protein PEST motif GABP-alpha PF11620.3 OAJ26043.1 - 0.041 13.8 3.9 28 4.7 0.1 3.1 3 0 0 3 3 3 0 GA-binding protein alpha chain EMG1 PF03587.9 OAJ26043.1 - 0.059 12.6 0.9 16 4.6 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase CTDII PF01556.13 OAJ26043.1 - 0.067 13.0 10.9 4.1 7.3 0.3 3.5 1 1 2 3 3 3 0 DnaJ C terminal domain Sortase PF04203.8 OAJ26043.1 - 0.14 11.7 1.6 23 4.5 0.0 3.0 1 1 2 3 3 3 0 Sortase family FERM_N PF09379.5 OAJ26043.1 - 0.39 10.8 9.5 37 4.4 0.2 4.7 3 3 0 3 3 3 0 FERM N-terminal domain DUF3781 PF12636.2 OAJ26043.1 - 0.55 10.2 3.9 82 3.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) eIF_4EBP PF05456.6 OAJ26044.1 - 3e-10 39.7 1.0 3e-10 39.7 0.7 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DDE_3 PF13358.1 OAJ26054.1 - 1.2e-28 99.7 0.0 2.8e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAJ26054.1 - 7.7e-09 36.2 0.2 5.2e-08 33.5 0.1 2.4 1 1 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 OAJ26054.1 - 1.6e-05 25.0 0.1 5.2e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Winged helix-turn helix rve PF00665.21 OAJ26054.1 - 3.9e-05 23.7 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain HTH_33 PF13592.1 OAJ26054.1 - 0.00062 19.2 0.1 0.0017 17.8 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.10 OAJ26054.1 - 0.018 14.8 0.0 0.15 11.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Tnp_IS630 PF01710.11 OAJ26054.1 - 0.022 14.4 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Transposase HTH_21 PF13276.1 OAJ26054.1 - 0.032 14.2 0.4 0.41 10.6 0.0 2.7 3 0 0 3 3 3 0 HTH-like domain HTH_Tnp_Tc3_2 PF01498.13 OAJ26054.1 - 0.065 13.2 1.5 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 Transposase RVT_1 PF00078.22 OAJ26055.1 - 2.2e-24 85.9 0.0 4.4e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNB PF00773.14 OAJ26056.1 - 1.9e-93 313.3 0.0 3.6e-93 312.4 0.0 1.5 1 0 0 1 1 1 1 RNB domain FlgN PF05130.7 OAJ26057.1 - 0.58 10.4 2.3 17 5.6 0.1 2.1 1 1 1 2 2 2 0 FlgN protein FANCF PF11107.3 OAJ26061.1 - 0.11 11.6 0.0 0.13 11.5 0.0 1.0 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) Hemerythrin PF01814.18 OAJ26063.1 - 0.029 14.5 0.2 0.045 13.9 0.2 1.3 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain TBPIP PF07106.8 OAJ26063.1 - 0.03 13.8 0.0 0.037 13.5 0.0 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ax_dynein_light PF10211.4 OAJ26063.1 - 0.059 13.2 0.3 0.076 12.8 0.2 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain WXG100 PF06013.7 OAJ26064.1 - 0.055 13.4 1.1 1.1 9.3 0.2 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Metal_resist PF13801.1 OAJ26064.1 - 0.49 10.3 5.5 0.13 12.2 1.2 1.8 2 0 0 2 2 2 0 Heavy-metal resistance Activator-TraM PF11657.3 OAJ26065.1 - 0.11 11.9 0.1 0.21 11.0 0.1 1.5 1 1 0 1 1 1 0 Transcriptional activator TraM SLT PF01464.15 OAJ26068.1 - 0.00044 19.7 1.0 0.0048 16.3 0.0 2.6 2 1 0 2 2 2 1 Transglycosylase SLT domain IGR PF09597.5 OAJ26071.1 - 5.7e-09 35.7 0.2 4e-08 33.0 0.1 2.2 2 0 0 2 2 2 1 IGR protein motif UBN2 PF14223.1 OAJ26073.1 - 1.9e-06 27.6 0.0 3.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ26073.1 - 2.1e-05 24.2 2.5 2.1e-05 24.2 1.8 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.1 OAJ26073.1 - 0.084 12.3 1.3 0.37 10.3 0.9 2.2 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger UBN2_2 PF14227.1 OAJ26073.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type rve PF00665.21 OAJ26075.1 - 2.4e-18 66.3 0.0 4.1e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ26075.1 - 0.00035 20.0 0.2 0.001 18.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RVT_2 PF07727.9 OAJ26076.1 - 1.9e-85 285.7 0.0 2.6e-85 285.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ26076.1 - 6.7e-23 81.0 0.6 3.2e-21 75.6 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ26076.1 - 2e-05 24.1 0.0 5.7e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ26076.1 - 0.0031 16.9 0.4 0.036 13.5 0.3 2.7 1 1 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ26076.1 - 0.041 13.2 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.5 OAJ26077.1 - 0.00026 20.1 8.4 0.0003 19.9 5.8 1.2 1 0 0 1 1 1 1 BUD22 Cwf_Cwc_15 PF04889.7 OAJ26077.1 - 0.012 15.2 6.3 0.018 14.7 4.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 OAJ26077.1 - 0.04 11.8 10.5 0.049 11.5 7.2 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.9 OAJ26077.1 - 0.043 13.3 4.5 0.075 12.5 3.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DDHD PF02862.12 OAJ26077.1 - 0.12 12.1 1.5 0.19 11.5 1.0 1.2 1 0 0 1 1 1 0 DDHD domain Daxx PF03344.10 OAJ26077.1 - 0.31 9.4 12.0 0.43 8.9 8.3 1.2 1 0 0 1 1 1 0 Daxx Family FLO_LFY PF01698.11 OAJ26077.1 - 0.6 8.8 3.4 0.82 8.4 2.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2457 PF10446.4 OAJ26077.1 - 0.78 8.4 14.0 1.1 7.9 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 OAJ26077.1 - 6.7 5.8 11.2 10 5.2 7.7 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.1 OAJ26077.1 - 7.1 6.2 6.2 15 5.2 4.3 1.5 1 0 0 1 1 1 0 FAM176 family NARP1 PF12569.3 OAJ26077.1 - 8 5.0 7.2 12 4.5 5.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Transposase_21 PF02992.9 OAJ26082.1 - 7.8e-15 54.5 0.1 3.3e-13 49.2 0.0 2.4 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ26082.1 - 6.4e-05 22.3 0.2 0.00012 21.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Zn-ribbon_8 PF09723.5 OAJ26082.1 - 0.11 12.5 0.9 0.27 11.1 0.6 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 OAJ26082.1 - 9.5 5.5 7.2 0.22 10.7 0.3 1.9 2 0 0 2 2 2 0 zinc-ribbon domain GTP_EFTU PF00009.22 OAJ26083.1 - 1.4e-60 203.9 0.3 2.4e-60 203.2 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 OAJ26083.1 - 3.4e-36 123.4 0.0 7.8e-36 122.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 OAJ26083.1 - 3.1e-21 75.0 0.0 7.7e-21 73.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 OAJ26083.1 - 1.8e-13 50.1 0.0 5.3e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 OAJ26083.1 - 1.2e-11 44.5 0.0 3.6e-11 43.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAJ26083.1 - 0.00011 22.1 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SH3_9 PF14604.1 OAJ26084.1 - 9.2e-06 25.1 0.1 0.00015 21.2 0.1 2.4 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ26084.1 - 2.8e-05 23.3 0.0 0.00013 21.2 0.0 2.1 2 0 0 2 2 2 1 SH3 domain Proteasome PF00227.21 OAJ26085.1 - 1.4e-59 200.6 0.0 2.3e-59 199.9 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 OAJ26085.1 - 3.1e-10 39.1 0.2 7.7e-10 37.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Fe-ADH PF00465.14 OAJ26086.1 - 4.1e-93 311.9 0.0 5.3e-93 311.5 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 OAJ26086.1 - 1.4e-13 50.7 0.0 2.1e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase GATA PF00320.22 OAJ26087.1 - 1.5e-13 49.8 3.4 2.8e-13 48.9 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger Caldesmon PF02029.10 OAJ26087.1 - 2.4e-07 29.5 0.1 2.6e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Caldesmon PAS PF00989.19 OAJ26087.1 - 4.9e-07 29.5 0.0 4.9e-07 29.5 0.0 3.3 2 1 0 2 2 1 1 PAS fold PAS_3 PF08447.6 OAJ26087.1 - 7.2e-05 22.8 0.0 7.2e-05 22.8 0.0 2.3 2 1 0 2 2 1 1 PAS fold SAPS PF04499.10 OAJ26087.1 - 0.0011 17.7 17.0 0.0016 17.1 11.8 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Mem_trans PF03547.13 OAJ26087.1 - 0.0025 16.1 0.1 0.0028 16.0 0.1 1.1 1 0 0 1 1 1 1 Membrane transport protein Spore_coat_CotO PF14153.1 OAJ26087.1 - 0.0091 15.4 29.8 0.017 14.6 20.6 1.3 1 0 0 1 1 1 1 Spore coat protein CotO PAS_4 PF08448.5 OAJ26087.1 - 0.011 15.7 0.0 0.011 15.7 0.0 2.3 2 1 0 2 2 1 0 PAS fold PAS_9 PF13426.1 OAJ26087.1 - 0.013 15.8 0.0 0.013 15.8 0.0 2.1 2 0 0 2 2 1 0 PAS domain Neur_chan_memb PF02932.11 OAJ26087.1 - 0.014 15.3 13.8 0.025 14.4 9.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TF_Zn_Ribbon PF08271.7 OAJ26087.1 - 0.043 13.1 0.3 0.2 10.9 0.0 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding HlyD_2 PF12700.2 OAJ26087.1 - 0.054 12.6 15.6 0.081 12.0 10.8 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF4045 PF13254.1 OAJ26087.1 - 0.098 11.9 20.3 0.18 11.0 14.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Med15 PF09606.5 OAJ26087.1 - 0.62 8.1 103.6 0.016 13.4 66.7 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal CRT10 PF08728.5 OAJ26087.1 - 2 6.3 11.9 2.7 5.8 8.2 1.1 1 0 0 1 1 1 0 CRT10 LMBR1 PF04791.11 OAJ26087.1 - 4.1 5.8 6.6 5.6 5.4 4.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RR_TM4-6 PF06459.7 OAJ26087.1 - 4.6 7.0 23.8 9.9 5.9 16.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 OAJ26087.1 - 6.6 4.6 23.1 9.8 4.0 16.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Exonuc_VII_L PF02601.10 OAJ26087.1 - 6.9 5.7 22.8 10 5.1 15.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit eIF-3_zeta PF05091.7 OAJ26087.1 - 7.8 4.9 29.0 12 4.3 20.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) UQ_con PF00179.21 OAJ26088.1 - 1.2e-46 157.5 0.0 1.4e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ26088.1 - 2.8e-06 27.1 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 OAJ26088.1 - 0.049 13.5 2.5 0.11 12.4 1.7 1.8 1 1 0 1 1 1 0 RWD domain HTH_Tnp_IS630 PF01710.11 OAJ26089.1 - 0.028 14.0 0.3 0.069 12.8 0.2 1.6 1 0 0 1 1 1 0 Transposase N-glycanase_N PF09112.5 OAJ26089.1 - 0.055 12.8 0.3 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Peptide-N-glycosidase F, N terminal eIF-3c_N PF05470.7 OAJ26090.1 - 0.2 9.6 3.3 0.26 9.3 2.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF3493 PF11998.3 OAJ26091.1 - 2.7 7.9 5.7 0.4 10.6 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) ADK PF00406.17 OAJ26092.1 - 2e-56 190.0 0.1 2.4e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 OAJ26092.1 - 1.9e-13 49.8 0.0 4.5e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid Zeta_toxin PF06414.7 OAJ26092.1 - 2.1e-05 23.7 0.0 3.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 OAJ26092.1 - 0.00047 20.0 0.0 0.001 18.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ26092.1 - 0.042 14.6 0.0 0.08 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 OAJ26092.1 - 0.043 14.0 0.1 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 OAJ26092.1 - 0.13 12.5 0.1 0.34 11.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain UCR_14kD PF02271.11 OAJ26093.1 - 5.6e-37 125.7 0.5 6.4e-37 125.5 0.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Amino_oxidase PF01593.19 OAJ26096.1 - 0.0002 20.5 0.2 0.0014 17.7 0.2 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase BicD PF09730.4 OAJ26097.1 - 0.0044 15.4 3.2 0.0048 15.3 2.2 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D CENP-F_leu_zip PF10473.4 OAJ26097.1 - 0.01 15.6 3.3 0.012 15.4 2.3 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 OAJ26097.1 - 0.044 13.5 6.4 0.052 13.2 4.4 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 OAJ26097.1 - 0.079 12.1 1.7 0.091 11.9 1.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Stathmin PF00836.14 OAJ26097.1 - 0.13 11.8 4.1 0.18 11.4 2.8 1.1 1 0 0 1 1 1 0 Stathmin family DUF612 PF04747.7 OAJ26097.1 - 0.81 8.5 5.3 0.96 8.2 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF612 CALCOCO1 PF07888.6 OAJ26097.1 - 1.1 7.5 3.8 1.2 7.3 2.7 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Amino_oxidase PF01593.19 OAJ26098.1 - 1.7e-08 34.0 0.1 8.4e-07 28.4 0.0 2.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAJ26098.1 - 2.7e-07 30.5 0.1 1.5e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ26098.1 - 2.4e-05 23.4 0.2 7.3e-05 21.8 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 OAJ26098.1 - 0.0033 16.1 0.0 0.0069 15.0 0.0 1.5 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.1 OAJ26098.1 - 0.0069 16.1 0.0 0.074 12.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 OAJ26098.1 - 0.0096 15.0 0.1 0.27 10.2 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase OCD_Mu_crystall PF02423.10 OAJ26098.1 - 0.052 12.3 0.0 0.088 11.5 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Pyr_redox PF00070.22 OAJ26098.1 - 0.12 12.7 0.1 2.9 8.3 0.2 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ26098.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DUF92 PF01940.11 OAJ26099.1 - 2.6e-30 105.2 2.5 3.5e-30 104.8 1.7 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 p450 PF00067.17 OAJ26101.1 - 2.7e-29 102.0 0.0 3e-23 82.0 0.0 2.4 1 1 1 2 2 2 2 Cytochrome P450 GMC_oxred_N PF00732.14 OAJ26102.1 - 5.2e-46 157.1 0.0 7.1e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ26102.1 - 3.8e-28 98.5 0.2 6.6e-28 97.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 OAJ26102.1 - 3.9e-05 23.5 0.2 0.00016 21.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAJ26102.1 - 0.00059 18.7 0.1 0.011 14.6 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 OAJ26102.1 - 0.00098 18.1 0.1 0.0062 15.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAJ26102.1 - 0.0019 18.1 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 OAJ26102.1 - 0.0036 15.6 0.0 0.006 14.9 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor FAD_binding_3 PF01494.14 OAJ26102.1 - 0.019 14.0 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 OAJ26102.1 - 0.02 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 OAJ26102.1 - 0.037 14.1 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 OAJ26102.1 - 0.062 12.2 0.0 0.096 11.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 OAJ26102.1 - 0.078 11.4 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.11 OAJ26102.1 - 0.091 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CopB PF05275.6 OAJ26102.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Copper resistance protein B precursor (CopB) F420_oxidored PF03807.12 OAJ26102.1 - 0.1 13.0 0.1 0.3 11.5 0.0 1.8 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent GIDA PF01134.17 OAJ26102.1 - 0.13 11.1 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Nol1_Nop2_Fmu PF01189.12 OAJ26103.1 - 3.5e-27 95.5 0.0 3.5e-17 62.6 0.0 3.9 3 1 1 4 4 4 4 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 OAJ26103.1 - 0.024 14.6 0.0 0.08 12.9 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 OAJ26103.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase ATP-synt_ab PF00006.20 OAJ26104.1 - 1.3e-69 233.9 0.0 2.2e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 OAJ26104.1 - 4.1e-23 82.0 0.0 1.4e-22 80.3 0.0 2.0 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 OAJ26104.1 - 4e-18 65.4 1.8 1e-17 64.0 1.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 OAJ26104.1 - 0.00028 20.7 0.5 0.00089 19.1 0.4 1.9 1 1 0 1 1 1 1 HAS barrel domain ICE2 PF08426.5 OAJ26105.1 - 3.6e-41 141.1 0.1 1.2e-37 129.5 0.0 3.6 1 1 0 1 1 1 1 ICE2 Myc_N PF01056.13 OAJ26105.1 - 4.4 6.3 6.4 3.2 6.8 0.3 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Myosin_tail_1 PF01576.14 OAJ26106.1 - 0.0029 15.4 0.3 0.004 14.9 0.2 1.1 1 0 0 1 1 1 1 Myosin tail DUF773 PF05600.7 OAJ26106.1 - 0.012 14.4 0.2 0.018 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF773) IncA PF04156.9 OAJ26106.1 - 0.018 14.6 0.3 0.029 13.9 0.2 1.3 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 OAJ26106.1 - 0.036 14.3 1.4 0.069 13.4 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Tropomyosin_1 PF12718.2 OAJ26106.1 - 0.04 13.7 0.2 0.069 13.0 0.1 1.3 1 0 0 1 1 1 0 Tropomyosin like Sec62 PF03839.11 OAJ26107.1 - 1.1e-44 152.5 6.3 3.5e-44 150.8 4.4 1.7 1 1 0 1 1 1 1 Translocation protein Sec62 COG6 PF06419.6 OAJ26108.1 - 2.7e-105 352.8 0.0 1.6e-88 297.4 0.0 2.8 2 1 0 2 2 2 2 Conserved oligomeric complex COG6 Exo70 PF03081.10 OAJ26108.1 - 0.015 14.0 0.0 0.047 12.4 0.0 1.8 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Carb_kinase PF01256.12 OAJ26109.1 - 6e-54 182.8 0.0 7.7e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 OAJ26109.1 - 0.00029 20.1 0.0 0.0015 17.7 0.0 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DUF4516 PF14990.1 OAJ26109.1 - 0.3 10.6 1.6 0.45 10.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) Daxx PF03344.10 OAJ26110.1 - 0.025 13.0 14.8 0.036 12.5 10.3 1.3 1 0 0 1 1 1 0 Daxx Family DUF92 PF01940.11 OAJ26111.1 - 2.6e-30 105.2 2.5 3.5e-30 104.8 1.7 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 RNA_pol_I_TF PF04090.7 OAJ26112.1 - 7.4e-06 25.3 0.0 6.8e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor PRP21_like_P PF12230.3 OAJ26121.1 - 1.5e-56 191.4 0.5 1.5e-56 191.4 0.4 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 OAJ26121.1 - 3.5e-32 109.8 0.3 3.2e-16 58.7 0.0 2.5 2 0 0 2 2 2 2 Surp module Erg28 PF03694.8 OAJ26122.1 - 7.3e-42 141.8 2.0 8.9e-42 141.5 1.4 1.1 1 0 0 1 1 1 1 Erg28 like protein S1FA PF04689.8 OAJ26122.1 - 0.045 13.6 0.2 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 DNA binding protein S1FA SAC3_GANP PF03399.11 OAJ26123.1 - 6.8e-42 143.3 0.0 1.2e-41 142.5 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Shadoo PF14999.1 OAJ26123.1 - 3.6 7.4 11.1 12 5.7 7.7 1.9 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Chorismate_bind PF00425.13 OAJ26124.1 - 2.3e-88 295.8 0.1 5.3e-88 294.6 0.0 1.6 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 OAJ26124.1 - 1.8e-25 89.5 0.0 1.3e-24 86.8 0.0 2.4 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region adh_short_C2 PF13561.1 OAJ26125.1 - 4.4e-28 98.6 0.1 4.4e-28 98.6 0.1 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ26125.1 - 2e-26 92.9 0.1 6.7e-26 91.1 0.1 2.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ26125.1 - 1.3e-11 44.4 0.1 4.8e-11 42.6 0.1 1.9 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAJ26125.1 - 0.00022 20.7 1.1 0.00045 19.7 0.1 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1687 PF07955.6 OAJ26126.1 - 7.7e-10 38.8 0.1 0.0018 18.2 0.0 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF1687) SDA1 PF05285.7 OAJ26127.1 - 0.053 12.7 7.4 3.6 6.7 4.1 2.3 2 0 0 2 2 2 0 SDA1 DDE_3 PF13358.1 OAJ26128.1 - 4e-14 52.5 0.0 8.9e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAJ26128.1 - 1.9e-05 25.3 0.2 7.3e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 OAJ26128.1 - 0.00039 20.5 0.0 0.0007 19.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_21 PF13276.1 OAJ26128.1 - 0.0065 16.4 0.4 0.013 15.4 0.3 1.4 1 0 0 1 1 1 1 HTH-like domain HTH_Tnp_Tc3_2 PF01498.13 OAJ26128.1 - 0.0092 16.0 0.4 0.016 15.2 0.3 1.3 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.1 OAJ26128.1 - 0.012 15.1 0.5 0.023 14.2 0.4 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_IS630 PF01710.11 OAJ26128.1 - 0.019 14.6 0.2 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 Transposase UBX PF00789.15 OAJ26129.1 - 1.1e-05 25.3 0.0 2.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 OAJ26129.1 - 0.00019 21.3 0.0 0.00055 19.9 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like SET PF00856.23 OAJ26130.1 - 0.0002 21.7 0.0 0.0041 17.4 0.0 2.8 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 OAJ26130.1 - 0.0053 16.6 0.2 0.033 14.1 0.2 2.0 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding Glyco_hydro_38 PF01074.17 OAJ26131.1 - 1.4e-76 257.3 0.7 2.3e-76 256.6 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 OAJ26131.1 - 2.6e-56 191.3 0.0 4.1e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 OAJ26131.1 - 2.4e-25 88.5 0.0 5.6e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain SIS PF01380.17 OAJ26132.1 - 1e-12 47.7 0.0 4e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.1 OAJ26132.1 - 0.00013 21.7 0.0 0.0045 16.7 0.0 2.3 1 1 0 1 1 1 1 SIS domain MFS_1 PF07690.11 OAJ26133.1 - 8.2e-29 100.4 24.2 8.2e-29 100.4 16.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 OAJ26133.1 - 0.56 8.1 7.4 24 2.8 5.1 2.2 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family F-box PF00646.28 OAJ26134.1 - 0.00062 19.3 1.9 0.011 15.3 0.1 2.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 OAJ26134.1 - 0.25 11.1 2.7 0.29 10.8 0.6 2.2 2 0 0 2 2 2 0 F-box-like SNARE_assoc PF09335.6 OAJ26136.1 - 2.2e-16 60.1 7.2 2.2e-16 60.1 5.0 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein Med5 PF08689.5 OAJ26136.1 - 1.2 6.7 10.9 1.9 6.0 7.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit Med5 Zip PF02535.17 OAJ26136.1 - 7.4 5.4 14.3 42 2.9 9.7 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter tRNA-synt_2 PF00152.15 OAJ26137.1 - 4.4e-102 341.2 0.0 1.2e-52 178.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAJ26137.1 - 4.9e-08 32.7 0.0 8.8e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 OAJ26137.1 - 0.00098 18.7 0.0 0.44 10.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) adh_short PF00106.20 OAJ26139.1 - 4.6e-16 59.1 0.8 6e-14 52.3 0.6 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ26139.1 - 1.5e-06 28.1 0.3 5.3e-06 26.3 0.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ26139.1 - 2.5e-05 23.9 0.1 6.6e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 KR domain ubiquitin PF00240.18 OAJ26139.1 - 0.038 13.3 0.1 0.071 12.5 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin family NAD_binding_10 PF13460.1 OAJ26139.1 - 0.06 13.3 0.1 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding MFS_1 PF07690.11 OAJ26140.1 - 0.00021 20.1 3.8 0.00031 19.5 2.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Pkinase_C PF00433.19 OAJ26141.1 - 0.00033 21.1 0.1 0.00052 20.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase C terminal domain Pea-VEAacid PF08111.6 OAJ26141.1 - 0.12 12.4 0.4 0.27 11.4 0.3 1.5 1 0 0 1 1 1 0 Pea-VEAacid family Cellulase PF00150.13 OAJ26142.1 - 7.3e-15 54.9 8.5 2.5e-14 53.1 5.9 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.13 OAJ26143.1 - 8.3e-17 61.2 0.1 3e-16 59.4 0.1 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BRCT PF00533.21 OAJ26144.1 - 1.5e-25 89.1 0.0 2.6e-10 40.2 0.0 5.0 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 OAJ26144.1 - 6e-23 80.4 0.1 3e-10 39.8 0.0 4.2 4 0 0 4 4 4 3 twin BRCT domain Methyltransf_16 PF10294.4 OAJ26145.1 - 1.2e-15 57.4 0.0 2e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 OAJ26145.1 - 0.13 11.3 0.1 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Cyclin PF08613.6 OAJ26150.1 - 3.9e-12 46.8 0.0 7.6e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 OAJ26150.1 - 4.4e-12 45.6 0.0 8.1e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3546 PF12066.3 OAJ26151.1 - 1.3e-14 54.1 0.3 3.9e-14 52.5 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 OAJ26151.1 - 0.00042 20.5 0.0 0.0015 18.7 0.0 2.0 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF4231 PF14015.1 OAJ26152.1 - 0.31 11.0 0.1 0.31 11.0 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DnaJ PF00226.26 OAJ26158.1 - 1.5e-18 66.3 0.3 2.8e-18 65.4 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DDHD PF02862.12 OAJ26161.1 - 5.6e-35 121.1 0.0 5.6e-35 121.1 0.0 3.5 2 1 0 2 2 2 1 DDHD domain Abhydrolase_5 PF12695.2 OAJ26161.1 - 0.078 12.7 0.0 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family CENP-B_dimeris PF09026.5 OAJ26161.1 - 2.3 8.4 34.8 2.4 8.4 2.8 4.5 4 0 0 4 4 4 0 Centromere protein B dimerisation domain MIP PF00230.15 OAJ26162.1 - 2.4e-05 23.9 9.0 4e-05 23.1 6.2 1.3 1 0 0 1 1 1 1 Major intrinsic protein DUF996 PF06195.8 OAJ26162.1 - 0.0086 16.0 0.7 0.017 15.1 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF996) F-box-like PF12937.2 OAJ26163.1 - 0.013 15.2 0.6 0.013 15.2 0.4 2.2 2 0 0 2 2 2 0 F-box-like BCDHK_Adom3 PF10436.4 OAJ26164.1 - 1.6e-42 144.7 0.0 2.4e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 OAJ26164.1 - 2.3e-13 49.7 0.0 3.4e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAJ26164.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Auts2 PF15336.1 OAJ26165.1 - 0.12 12.4 0.4 0.12 12.4 0.3 2.6 1 1 2 3 3 3 0 Autism susceptibility gene 2 protein ING PF12998.2 OAJ26167.1 - 2.4e-10 40.6 0.0 4.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 OAJ26167.1 - 3.2e-09 36.3 9.0 5.3e-09 35.6 6.2 1.4 1 0 0 1 1 1 1 PHD-finger MOSC_N PF03476.11 OAJ26168.1 - 1.9e-20 72.7 0.0 2.9e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 OAJ26168.1 - 7.5e-11 41.6 1.9 3.3e-05 23.3 0.0 2.9 2 1 0 2 2 2 2 MOSC domain Nop16 PF09420.5 OAJ26169.1 - 7.6e-35 120.4 0.0 9.3e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Nop PF01798.13 OAJ26170.1 - 1e-54 183.9 1.0 2.4e-54 182.7 0.7 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 OAJ26170.1 - 5.8e-26 90.0 0.1 1e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 OAJ26170.1 - 6.1e-11 42.3 0.0 1.9e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Abhydrolase_5 PF12695.2 OAJ26171.1 - 0.00027 20.6 0.0 0.0015 18.2 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 OAJ26171.1 - 0.0003 20.3 0.0 0.00061 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 OAJ26171.1 - 0.0079 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ26171.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1421 PF07223.6 OAJ26171.1 - 5 6.8 6.7 5.4 6.6 3.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1421) Fungal_trans PF04082.13 OAJ26173.1 - 1.8e-28 99.1 0.0 3.7e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ26173.1 - 3.7e-08 33.1 6.1 6.4e-08 32.3 4.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DSBA PF01323.15 OAJ26173.1 - 0.072 12.6 0.2 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 DSBA-like thioredoxin domain WD40 PF00400.27 OAJ26174.1 - 1.8e-38 129.0 8.5 1.3e-08 34.4 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Sof1 PF04158.9 OAJ26174.1 - 2.1e-24 85.3 11.2 3.2e-24 84.7 7.8 1.3 1 0 0 1 1 1 1 Sof1-like domain Nucleoporin_N PF08801.6 OAJ26174.1 - 0.0041 15.9 0.1 1.5 7.4 0.0 3.1 2 2 0 4 4 4 2 Nup133 N terminal like Me-amine-dh_H PF06433.6 OAJ26174.1 - 0.037 12.6 0.0 0.053 12.1 0.0 1.2 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) AFG1_ATPase PF03969.11 OAJ26175.1 - 3.6e-56 190.5 0.1 3.8e-42 144.4 0.0 4.0 3 1 0 3 3 3 3 AFG1-like ATPase AAA_16 PF13191.1 OAJ26175.1 - 3.2e-08 33.7 0.5 1.2e-07 31.9 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAJ26175.1 - 1.5e-05 25.1 0.0 0.019 15.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 OAJ26175.1 - 0.00011 21.9 0.0 0.032 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 OAJ26175.1 - 0.0011 19.1 0.0 0.021 15.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 OAJ26175.1 - 0.0027 17.7 0.0 2.1 8.3 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 OAJ26175.1 - 0.0047 16.1 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 OAJ26175.1 - 0.006 16.0 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 OAJ26175.1 - 0.0062 16.2 0.0 0.034 13.8 0.0 2.3 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 OAJ26175.1 - 0.026 13.9 0.4 1.4 8.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 OAJ26175.1 - 0.039 13.8 0.0 9.1 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain GATase_7 PF13537.1 OAJ26175.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase domain IstB_IS21 PF01695.12 OAJ26175.1 - 0.13 11.6 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 OAJ26175.1 - 0.26 9.9 0.0 15 4.1 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus SR-25 PF10500.4 OAJ26175.1 - 1.5 8.2 19.9 0.011 15.1 4.9 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Methyltransf_11 PF08241.7 OAJ26176.1 - 3e-09 37.2 0.0 5.2e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ26176.1 - 8.8e-07 28.7 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ26176.1 - 1.2e-05 25.5 0.1 2.6e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ26176.1 - 0.00015 22.3 0.2 0.00021 21.8 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ26176.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ26176.1 - 0.0016 18.8 0.0 0.005 17.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 OAJ26176.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MOR2-PAG1_N PF14222.1 OAJ26178.1 - 8.7e-114 381.1 0.0 1.6e-113 380.3 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 OAJ26178.1 - 2e-61 208.0 3.8 2e-61 208.0 2.7 3.1 3 1 1 4 4 4 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 OAJ26178.1 - 2.2e-20 71.9 1.2 7.6e-07 27.1 0.0 4.8 5 0 0 5 5 5 4 Cell morphogenesis central region RVT_1 PF00078.22 OAJ26179.1 - 8.5e-24 84.1 0.0 1.6e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAJ26179.1 - 2.6e-17 63.4 0.1 8e-17 61.8 0.0 1.9 2 0 0 2 2 2 1 RNase H Exo_endo_phos_2 PF14529.1 OAJ26179.1 - 7.3e-16 57.8 0.1 2.1e-15 56.3 0.1 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ26179.1 - 3.1e-07 30.5 0.7 1.4e-06 28.4 0.2 2.2 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 OAJ26179.1 - 0.082 12.8 3.2 0.29 11.1 2.2 2.0 1 0 0 1 1 1 0 Zinc knuckle zf-RVT PF13966.1 OAJ26179.1 - 1.9 8.8 11.1 0.18 12.1 0.8 2.8 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase G-patch PF01585.18 OAJ26180.1 - 0.0021 17.7 1.0 0.0075 16.0 0.7 2.0 1 0 0 1 1 1 1 G-patch domain SHS2_Rpb7-N PF03876.12 OAJ26182.1 - 3.4e-14 52.7 0.0 5.5e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 OAJ26182.1 - 4.5e-11 42.6 0.1 6.5e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 OAJ26182.1 - 0.033 14.3 0.0 0.049 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Fun_ATP-synt_8 PF05933.8 OAJ26183.1 - 0.014 15.4 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) RINT1_TIP1 PF04437.8 OAJ26184.1 - 6.2e-40 137.1 0.0 2e-26 92.6 0.0 4.2 2 1 0 2 2 2 2 RINT-1 / TIP-1 family PBP1_TM PF14812.1 OAJ26184.1 - 0.099 12.9 1.1 0.29 11.4 0.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Abhydrolase_6 PF12697.2 OAJ26185.1 - 1.1e-07 31.9 0.6 2.3e-07 30.9 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ26185.1 - 4.2e-05 23.3 0.1 6.9e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 OAJ26185.1 - 0.014 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF1749 PF08538.5 OAJ26185.1 - 0.034 13.0 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Fic_N PF13784.1 OAJ26186.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Fic/DOC family N-terminal MAGP PF05507.6 OAJ26186.1 - 0.16 11.7 0.3 0.53 10.1 0.0 2.0 2 0 0 2 2 2 0 Microfibril-associated glycoprotein (MAGP) Ribosomal_S4e PF00900.15 OAJ26191.1 - 1e-29 102.0 0.6 2.1e-29 100.9 0.1 1.8 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 OAJ26191.1 - 7.1e-20 70.5 3.6 1.3e-19 69.7 2.5 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.24 OAJ26191.1 - 0.00027 20.5 1.0 0.0008 19.0 0.7 1.9 1 0 0 1 1 1 1 KOW motif S4 PF01479.20 OAJ26191.1 - 0.0075 15.6 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 S4 domain Chitin_synth_1 PF01644.12 OAJ26192.1 - 8.3e-67 224.0 0.0 1.3e-66 223.3 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 OAJ26192.1 - 1.4e-25 88.7 0.0 2.5e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 OAJ26192.1 - 6e-24 84.3 3.0 5.5e-17 61.3 0.0 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 OAJ26192.1 - 4.6e-11 42.7 7.8 4.7e-11 42.7 0.1 2.4 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ26192.1 - 4e-05 23.5 0.0 7.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 YhjQ PF06564.7 OAJ26192.1 - 0.081 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 YhjQ protein ABC1 PF03109.11 OAJ26193.1 - 4.9e-18 65.2 0.1 2.3e-08 34.0 0.0 2.7 2 0 0 2 2 2 2 ABC1 family Mago-bind PF09282.5 OAJ26194.1 - 9.5e-12 44.2 2.4 9.5e-12 44.2 1.6 1.9 2 0 0 2 2 2 1 Mago binding CAF1-p150_C2 PF15539.1 OAJ26194.1 - 0.033 13.3 1.3 0.057 12.5 0.9 1.4 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term DUF605 PF04652.11 OAJ26194.1 - 0.066 12.6 15.5 0.075 12.4 10.7 1.1 1 0 0 1 1 1 0 Vta1 like BSP_II PF05432.6 OAJ26194.1 - 0.12 11.6 5.9 0.19 11.0 4.1 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Med3 PF11593.3 OAJ26194.1 - 0.14 11.3 19.0 0.034 13.3 8.4 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal PBP1_TM PF14812.1 OAJ26194.1 - 0.49 10.7 3.9 1.4 9.2 2.7 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 OAJ26194.1 - 1.8 6.3 7.0 2.1 6.1 4.9 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 OAJ26194.1 - 6.1 6.0 5.8 8.6 5.5 4.0 1.1 1 0 0 1 1 1 0 NOA36 protein CMAS PF02353.15 OAJ26195.1 - 3.2e-62 210.1 0.1 3.9e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 OAJ26195.1 - 4.3e-15 55.7 0.0 8.5e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ26195.1 - 1.7e-09 38.0 0.0 5.6e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ26195.1 - 8.2e-08 32.5 0.0 1.6e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ26195.1 - 1.6e-07 31.8 0.0 3.3e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ26195.1 - 3.3e-07 30.3 0.1 1.2e-06 28.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ26195.1 - 3.2e-06 26.7 0.0 5.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ26195.1 - 1.1e-05 25.8 0.0 2.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 OAJ26195.1 - 0.00015 21.1 0.0 0.00038 19.8 0.0 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 PCMT PF01135.14 OAJ26195.1 - 0.0008 19.0 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 OAJ26195.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 OAJ26195.1 - 0.0074 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 OAJ26195.1 - 0.15 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FA_desaturase PF00487.19 OAJ26196.1 - 6.7e-33 114.2 17.3 3.5e-32 111.8 12.0 2.2 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 OAJ26196.1 - 1.3e-08 34.4 0.0 4.6e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain PQ-loop PF04193.9 OAJ26197.1 - 2e-23 81.7 0.6 4.7e-13 48.4 0.0 2.7 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 OAJ26197.1 - 0.48 10.3 2.8 0.67 9.8 0.3 2.3 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Zn_clus PF00172.13 OAJ26198.1 - 6.6e-05 22.7 11.6 0.00011 21.9 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM176 PF14851.1 OAJ26198.1 - 6.7 6.3 6.3 23 4.6 0.7 2.7 2 0 0 2 2 2 0 FAM176 family TPR_2 PF07719.12 OAJ26199.1 - 2.7e-07 29.9 0.7 0.81 9.7 0.1 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ26199.1 - 8.5e-06 25.9 11.2 0.68 10.7 0.0 5.2 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ26199.1 - 9.3e-05 22.9 5.5 0.35 11.6 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ26199.1 - 0.00036 20.1 0.3 15 5.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ26199.1 - 0.00097 18.7 1.0 4.4 7.0 0.2 3.7 3 1 1 4 4 4 3 TPR repeat TPR_19 PF14559.1 OAJ26199.1 - 0.0059 16.9 8.7 15 6.0 0.1 4.9 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ26199.1 - 0.028 14.0 0.7 34 4.2 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ26199.1 - 0.058 13.2 2.1 8.7 6.2 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_C48 PF02902.14 OAJ26200.1 - 6.1e-24 84.8 0.1 2.2e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain F-actin_cap_A PF01267.12 OAJ26201.1 - 2e-63 213.9 0.0 3.4e-63 213.2 0.0 1.3 1 1 0 1 1 1 1 F-actin capping protein alpha subunit Slx4 PF09494.5 OAJ26203.1 - 4e-08 32.8 0.0 2.3e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Slx4 endonuclease Sigma70_ner PF04546.8 OAJ26203.1 - 0.85 9.1 12.5 3 7.3 2.2 3.2 3 0 0 3 3 3 0 Sigma-70, non-essential region Nop14 PF04147.7 OAJ26203.1 - 7.1 4.4 17.9 0.29 9.0 8.3 1.6 2 0 0 2 2 2 0 Nop14-like family Mito_carr PF00153.22 OAJ26205.1 - 1.7e-46 155.8 0.9 9.4e-16 57.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PQ-loop PF04193.9 OAJ26206.1 - 8.3e-30 102.1 1.2 5.8e-17 60.9 0.3 2.6 2 0 0 2 2 2 2 PQ loop repeat PQ-loop PF04193.9 OAJ26207.1 - 1.9e-24 84.9 5.1 8.1e-17 60.5 0.4 3.5 3 0 0 3 3 3 3 PQ loop repeat NADH-u_ox-rdase PF10785.4 OAJ26207.1 - 0.063 13.5 1.8 0.27 11.4 0.1 2.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Cellulase PF00150.13 OAJ26208.1 - 5.7e-07 29.0 2.0 1.2e-06 27.9 1.4 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.13 OAJ26209.1 - 3.3e-06 26.5 1.4 5.9e-06 25.6 1.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TMEM154 PF15102.1 OAJ26210.1 - 0.011 15.4 0.1 0.062 12.9 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family SR-25 PF10500.4 OAJ26211.1 - 1.9 7.8 23.9 2.5 7.5 4.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TSA PF03249.8 OAJ26211.1 - 3.5 6.0 8.9 6 5.2 6.2 1.3 1 0 0 1 1 1 0 Type specific antigen ORMDL PF04061.9 OAJ26212.1 - 2.6e-34 117.7 0.4 3.1e-34 117.4 0.3 1.1 1 0 0 1 1 1 1 ORMDL family Sds3 PF08598.6 OAJ26213.1 - 0.036 13.5 0.4 0.055 12.9 0.3 1.2 1 0 0 1 1 1 0 Sds3-like TT_ORF2 PF02957.10 OAJ26213.1 - 0.16 12.6 0.2 0.16 12.6 0.1 2.3 1 1 2 3 3 3 0 TT viral ORF2 DUF4414 PF14377.1 OAJ26213.1 - 2.1 8.3 5.8 21 5.1 1.7 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4414) DDE_Tnp_4 PF13359.1 OAJ26214.1 - 1e-34 119.4 0.0 1.4e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 OAJ26214.1 - 3.8e-07 29.8 0.0 7.8e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.9 OAJ26214.1 - 3.9e-06 26.3 0.0 8.5e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 Plant transposon protein Asp PF00026.18 OAJ26217.1 - 3.1e-41 141.6 0.0 8.3e-41 140.2 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ26217.1 - 0.00014 21.9 0.2 0.00014 21.9 0.2 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAJ26217.1 - 0.0063 16.9 0.1 2.1 8.9 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease Abhydrolase_6 PF12697.2 OAJ26218.1 - 3.4e-24 85.9 0.6 6.3e-24 85.1 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ26218.1 - 1.1e-22 80.7 0.0 3.1e-22 79.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ26218.1 - 1.9e-13 50.3 0.0 1.3e-12 47.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 OAJ26218.1 - 0.0073 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 OAJ26218.1 - 0.092 12.6 0.0 0.22 11.3 0.0 1.6 1 1 0 1 1 1 0 Putative lysophospholipase Peptidase_S28 PF05577.7 OAJ26218.1 - 0.25 9.8 0.0 0.36 9.3 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Zn_clus PF00172.13 OAJ26219.1 - 0.0001 22.1 10.3 0.00018 21.3 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.18 OAJ26220.1 - 1.3e-17 63.5 0.9 3.3e-17 62.2 0.6 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAJ26220.1 - 4e-12 45.8 0.3 9.7e-12 44.6 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 OAJ26220.1 - 0.045 12.9 0.0 0.097 11.7 0.0 1.5 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding PH PF00169.24 OAJ26221.1 - 8.8e-08 32.3 0.0 2.4e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_7 PF15408.1 OAJ26221.1 - 0.066 13.0 0.0 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain SOG2 PF10428.4 OAJ26229.1 - 2.1e-70 237.6 12.5 1.6e-55 188.5 0.0 3.7 4 0 0 4 4 4 2 RAM signalling pathway protein LRR_4 PF12799.2 OAJ26229.1 - 1.1e-12 47.2 5.9 2.7e-06 26.8 0.0 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ26229.1 - 1.4e-12 47.1 2.0 5.8e-09 35.5 0.1 3.0 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 OAJ26229.1 - 5.1e-07 28.8 2.0 0.92 9.7 0.0 5.3 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 OAJ26229.1 - 7.9e-05 22.2 0.4 8.3 7.1 0.0 4.9 4 0 0 4 4 4 2 Leucine rich repeat HDA2-3 PF11496.3 OAJ26229.1 - 0.037 12.8 0.8 0.053 12.3 0.0 1.6 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Peptidase_M22 PF00814.20 OAJ26230.1 - 1e-73 248.1 0.0 5.2e-73 245.8 0.0 1.8 1 1 0 1 1 1 1 Glycoprotease family MOZ_SAS PF01853.13 OAJ26231.1 - 2.7e-79 264.8 0.1 3.8e-79 264.3 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family Ribosomal_60s PF00428.14 OAJ26231.1 - 0.013 15.9 0.5 0.013 15.9 0.3 3.7 3 1 0 3 3 3 0 60s Acidic ribosomal protein Adeno_terminal PF02459.10 OAJ26231.1 - 0.41 8.7 1.3 0.59 8.2 0.9 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein VRR_NUC PF08774.6 OAJ26232.1 - 3.8e-18 65.3 0.1 1.2e-17 63.7 0.0 1.9 1 0 0 1 1 1 1 VRR-NUC domain Memo PF01875.12 OAJ26233.1 - 1.1e-70 237.6 0.0 2.8e-70 236.3 0.0 1.6 1 1 0 1 1 1 1 Memo-like protein ECH PF00378.15 OAJ26234.1 - 1.3e-14 53.9 0.0 2.7e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Formyl_trans_N PF00551.14 OAJ26234.1 - 3.6e-11 42.9 0.0 5.7e-10 39.0 0.0 2.5 1 1 1 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.13 OAJ26234.1 - 0.0012 18.8 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain MIF4G PF02854.14 OAJ26237.1 - 1.3e-54 184.8 0.1 1.9e-28 99.3 0.0 3.3 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 OAJ26237.1 - 1.7e-23 83.2 12.6 4.8e-23 81.7 8.7 1.8 1 0 0 1 1 1 1 Up-frameshift suppressor 2 Daxx PF03344.10 OAJ26237.1 - 0.00024 19.7 16.7 0.00054 18.6 11.5 1.5 1 0 0 1 1 1 1 Daxx Family Nucleoplasmin PF03066.10 OAJ26237.1 - 0.033 13.7 14.6 0.091 12.2 10.1 1.7 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 OAJ26237.1 - 0.061 11.3 16.4 0.12 10.3 10.6 1.9 2 0 0 2 2 2 0 CDC45-like protein Zn_clus PF00172.13 OAJ26238.1 - 1.8e-06 27.7 7.2 3.1e-06 27.0 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YL1 PF05764.8 OAJ26239.1 - 7.3e-39 133.7 20.9 1e-38 133.3 14.5 1.2 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.6 OAJ26239.1 - 5.8e-09 35.3 0.0 9.7e-09 34.6 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF1484 PF07363.6 OAJ26239.1 - 2.3 8.5 4.4 3 8.2 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) Peptidase_M19 PF01244.16 OAJ26240.1 - 1e-93 313.8 0.0 1.2e-93 313.6 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) PCMT PF01135.14 OAJ26242.1 - 4.1e-64 215.9 0.0 1.5e-62 210.8 0.0 2.0 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 OAJ26242.1 - 0.00013 22.4 0.1 0.0037 17.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ26242.1 - 0.015 15.3 0.0 0.034 14.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ26242.1 - 0.058 13.1 0.0 0.089 12.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ26242.1 - 0.075 12.6 0.1 0.23 11.0 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain DNA_ligase_A_M PF01068.16 OAJ26243.1 - 2.7e-17 62.8 0.0 1.4e-08 34.4 0.0 4.2 3 1 0 3 3 3 3 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 OAJ26243.1 - 0.0053 16.5 0.1 0.022 14.5 0.0 2.1 2 1 0 2 2 2 1 DNA ligase N terminus PIG-H PF10181.4 OAJ26244.1 - 4.8e-07 29.3 0.0 2.9e-06 26.7 0.0 2.1 1 1 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component ADH_zinc_N PF00107.21 OAJ26245.1 - 3.9e-19 68.4 1.3 8.2e-19 67.4 0.9 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ26245.1 - 9.4e-10 39.4 0.3 2e-09 38.4 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ26245.1 - 0.00053 19.7 0.0 0.0029 17.3 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DIE2_ALG10 PF04922.7 OAJ26246.1 - 4.1e-99 332.1 10.1 2.8e-74 250.4 6.1 2.0 2 0 0 2 2 2 2 DIE2/ALG10 family LexA_DNA_bind PF01726.11 OAJ26246.1 - 0.099 12.2 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain DUF572 PF04502.8 OAJ26247.1 - 0.83 8.8 4.1 1 8.5 2.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) FKBP_N PF01346.13 OAJ26247.1 - 0.96 9.5 6.0 1.9 8.5 4.2 1.5 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase TEX13 PF15186.1 OAJ26247.1 - 1.1 8.8 8.6 1.2 8.7 5.4 1.4 1 1 0 1 1 1 0 Testis-expressed sequence 13 protein family Nramp PF01566.13 OAJ26248.1 - 9.2e-89 297.7 26.8 1.7e-48 165.2 8.4 2.9 2 1 0 2 2 2 2 Natural resistance-associated macrophage protein CSF-1 PF05337.6 OAJ26248.1 - 0.14 11.5 0.4 3 7.0 0.0 2.3 2 0 0 2 2 2 0 Macrophage colony stimulating factor-1 (CSF-1) Myosin_tail_1 PF01576.14 OAJ26249.1 - 0.016 12.9 3.2 0.026 12.2 2.2 1.2 1 0 0 1 1 1 0 Myosin tail SET PF00856.23 OAJ26250.1 - 3.1e-19 69.8 1.0 1.9e-18 67.2 0.0 2.6 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.11 OAJ26250.1 - 2.3e-16 59.9 6.2 2.3e-16 59.9 4.3 2.1 2 0 0 2 2 2 1 Pre-SET motif Nucleoporin_C PF03177.9 OAJ26251.1 - 1.4e-53 182.3 4.9 2e-53 181.8 3.4 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 OAJ26251.1 - 5.1e-16 58.4 0.0 1e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Nup133 N terminal like YkyA PF10368.4 OAJ26251.1 - 0.22 10.8 1.4 0.5 9.6 1.0 1.5 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Mito_carr PF00153.22 OAJ26252.1 - 1.3e-50 169.0 5.8 2.9e-18 65.3 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein zf-H2C2_2 PF13465.1 OAJ26253.1 - 7.8e-23 79.5 13.2 7.2e-06 26.0 0.5 4.9 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ26253.1 - 1.9e-20 71.8 22.4 9.5e-05 22.5 1.5 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ26253.1 - 1.9e-12 46.5 20.2 0.0017 18.5 0.3 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 OAJ26253.1 - 0.014 15.2 13.7 0.11 12.4 0.6 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-TRAF PF02176.13 OAJ26253.1 - 0.057 13.8 6.5 0.059 13.7 0.6 2.8 1 1 2 3 3 3 0 TRAF-type zinc finger Nop14 PF04147.7 OAJ26253.1 - 0.24 9.2 9.6 0.39 8.5 6.7 1.2 1 0 0 1 1 1 0 Nop14-like family FYDLN_acid PF09538.5 OAJ26253.1 - 0.8 10.3 13.5 0.11 13.1 5.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-met PF12874.2 OAJ26253.1 - 2.7 8.3 14.2 5.4 7.3 0.3 4.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Chromo PF00385.19 OAJ26255.1 - 5.6e-15 54.7 2.2 1.3e-14 53.5 1.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 OAJ26255.1 - 4.4e-11 42.4 0.0 1.3e-09 37.7 0.0 2.4 2 0 0 2 2 2 1 Chromo shadow domain DUF1682 PF07946.9 OAJ26256.1 - 1.3e-51 175.4 0.0 1.5e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF3835 PF12927.2 OAJ26257.1 - 1.1e-07 32.6 13.2 1e-05 26.3 0.1 4.8 5 1 1 6 6 6 2 Domain of unknown function (DUF3835) Secretogranin_V PF05281.6 OAJ26257.1 - 0.022 14.1 0.4 0.045 13.1 0.3 1.5 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) Nucleo_P87 PF07267.6 OAJ26257.1 - 0.51 8.9 1.5 0.91 8.1 1.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ank_2 PF12796.2 OAJ26258.1 - 2.6e-16 59.7 0.4 3.7e-13 49.6 0.2 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ26258.1 - 1.3e-14 53.1 3.1 3.9e-08 32.6 0.2 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 OAJ26258.1 - 1.3e-14 54.2 1.3 3.5e-10 40.1 0.3 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ26258.1 - 2.5e-11 42.6 0.8 7.6e-05 22.5 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 OAJ26258.1 - 1.8e-08 34.3 5.2 7e-06 26.1 0.4 4.3 3 2 2 5 5 5 2 Ankyrin repeats (many copies) DUF2222 PF09984.4 OAJ26258.1 - 0.13 11.6 0.1 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) Glyco_tranf_2_3 PF13641.1 OAJ26264.1 - 3.9e-25 89.0 0.0 5.6e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 OAJ26264.1 - 3.4e-09 36.2 0.1 1.2e-08 34.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 OAJ26264.1 - 3.9e-09 36.4 0.0 6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 OAJ26264.1 - 1.5e-06 28.0 5.5 1.5e-06 28.0 3.8 1.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.10 OAJ26264.1 - 0.0037 15.6 0.1 0.023 13.1 0.0 1.8 1 1 0 1 1 1 1 Chitin synthase Vps8 PF12816.2 OAJ26265.1 - 2e-50 170.7 0.0 3.1e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 OAJ26265.1 - 0.021 14.4 0.2 2 8.0 0.0 2.3 2 0 0 2 2 2 0 Region in Clathrin and VPS DUF605 PF04652.11 OAJ26265.1 - 3.1 7.1 22.9 9.1 5.5 0.2 2.6 2 0 0 2 2 2 0 Vta1 like Kin17_mid PF10357.4 OAJ26266.1 - 2.7e-44 149.8 0.1 5.5e-44 148.8 0.0 1.5 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 OAJ26266.1 - 0.036 14.1 2.3 0.066 13.3 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 OAJ26266.1 - 0.11 12.6 1.3 0.17 12.0 0.1 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) His_Phos_1 PF00300.17 OAJ26268.1 - 6.1e-19 68.6 0.2 3.3e-18 66.2 0.0 2.1 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) PalH PF08733.5 OAJ26269.1 - 0.0043 15.9 6.2 0.01 14.7 4.2 1.5 1 1 0 1 1 1 1 PalH/RIM21 F-box-like PF12937.2 OAJ26270.1 - 6.4e-09 35.4 0.1 6.4e-09 35.4 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ26270.1 - 7.1e-07 28.7 0.9 6.2e-06 25.7 0.0 2.7 3 0 0 3 3 3 1 F-box domain PQQ PF01011.16 OAJ26270.1 - 0.0014 18.0 0.1 1 9.0 0.1 2.6 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.1 OAJ26270.1 - 0.0017 17.8 0.1 0.85 9.0 0.0 2.3 2 0 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 OAJ26270.1 - 0.13 12.5 2.2 1.6e+02 2.7 0.0 5.0 5 0 0 5 5 5 0 PQQ-like domain MutS_V PF00488.16 OAJ26271.1 - 1.5e-95 319.0 0.0 2.3e-95 318.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAJ26271.1 - 9.6e-36 123.4 2.5 2.4e-35 122.1 0.2 2.3 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 OAJ26271.1 - 6.5e-19 67.8 0.4 2.4e-18 66.0 0.0 2.3 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 OAJ26271.1 - 2.3e-15 56.8 0.1 7.7e-15 55.1 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.15 OAJ26271.1 - 3.3e-15 56.0 0.0 1.2e-14 54.2 0.0 2.1 1 0 0 1 1 1 1 MutS domain I Syntaxin PF00804.20 OAJ26271.1 - 0.058 13.5 2.4 3.9 7.6 0.6 2.8 2 0 0 2 2 2 0 Syntaxin TBCA PF02970.11 OAJ26271.1 - 1.6 8.8 8.2 98 3.1 0.0 3.7 3 0 0 3 3 3 0 Tubulin binding cofactor A DUF2315 PF10231.4 OAJ26272.1 - 1.2e-08 34.8 2.4 0.00012 21.9 0.8 2.6 2 1 0 2 2 2 2 Uncharacterised conserved protein (DUF2315) Aft1_OSA PF11785.3 OAJ26272.1 - 1.5 9.4 11.6 0.93 10.0 0.3 2.8 3 0 0 3 3 3 0 Aft1 osmotic stress response (OSM) domain SAM_1 PF00536.25 OAJ26273.1 - 0.00029 20.9 0.2 0.00064 19.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 OAJ26273.1 - 0.0034 17.1 0.1 0.0077 16.0 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Yippee-Mis18 PF03226.9 OAJ26274.1 - 1.9e-14 53.4 0.3 3.8e-14 52.4 0.0 1.6 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MS_channel PF00924.13 OAJ26275.1 - 6.2e-15 55.0 0.5 1.5e-14 53.7 0.4 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 OAJ26275.1 - 0.00015 20.7 0.1 0.00035 19.6 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 OAJ26275.1 - 0.0024 17.6 0.0 0.0075 16.0 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 OAJ26275.1 - 0.0089 16.1 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 OAJ26275.1 - 0.015 14.5 0.1 0.035 13.4 0.1 1.6 1 0 0 1 1 1 0 EF hand CDK2AP PF09806.4 OAJ26275.1 - 1.4 9.0 12.7 0.24 11.5 4.5 2.3 3 0 0 3 3 3 0 Cyclin-dependent kinase 2-associated protein Zip PF02535.17 OAJ26275.1 - 2.4 7.0 17.5 0.8 8.6 9.2 2.3 1 1 1 2 2 2 0 ZIP Zinc transporter bZIP_1 PF00170.16 OAJ26276.1 - 0.00019 21.2 21.5 0.00067 19.5 9.6 2.7 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 OAJ26276.1 - 0.19 11.5 24.8 0.087 12.6 9.8 3.3 2 0 0 2 2 2 0 Basic region leucine zipper PHD PF00628.24 OAJ26277.1 - 5.1e-08 32.4 7.2 8.5e-08 31.7 5.0 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 OAJ26277.1 - 2e-06 27.9 0.0 4.7e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD_2 PF13831.1 OAJ26277.1 - 0.02 14.2 1.6 0.035 13.4 1.1 1.5 1 0 0 1 1 1 0 PHD-finger MS_channel PF00924.13 OAJ26278.1 - 1.1e-22 80.4 0.0 1.6e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 OAJ26278.1 - 0.012 14.8 0.0 0.028 13.7 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 OAJ26278.1 - 0.02 14.7 0.0 0.068 13.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain Orthopox_F8 PF05886.6 OAJ26278.1 - 3.7 7.4 6.1 40 4.1 2.2 2.7 2 0 0 2 2 2 0 Orthopoxvirus F8 protein PI31_Prot_N PF11566.3 OAJ26280.1 - 5.3e-34 117.0 0.0 6.9e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 OAJ26280.1 - 5.1e-15 55.8 19.0 5.1e-15 55.8 13.2 2.9 3 0 0 3 3 3 1 PI31 proteasome regulator F-box PF00646.28 OAJ26281.1 - 0.004 16.7 0.1 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain SPC12 PF06645.8 OAJ26282.1 - 3.2e-24 84.5 0.1 3.8e-24 84.2 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2892 PF11127.3 OAJ26282.1 - 0.00088 19.0 0.5 0.0012 18.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) Aa_trans PF01490.13 OAJ26283.1 - 7e-72 242.1 18.9 9.8e-72 241.6 13.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 OAJ26283.1 - 2.6e-05 23.2 17.5 5.8e-05 22.0 12.1 1.7 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Myb_DNA-binding PF00249.26 OAJ26284.1 - 3.8e-07 30.0 0.0 7.8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rcd1 PF04078.8 OAJ26286.1 - 1.5e-125 417.3 1.3 2e-125 416.9 0.9 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Mog1 PF04603.7 OAJ26287.1 - 9.4e-31 106.6 0.0 2e-30 105.6 0.0 1.5 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Thioredoxin PF00085.15 OAJ26288.1 - 3.4e-27 94.1 0.0 8.6e-26 89.6 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 OAJ26288.1 - 4.9e-05 23.3 0.0 0.00018 21.5 0.0 1.9 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ26288.1 - 0.00025 21.2 0.0 0.0012 19.0 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 OAJ26288.1 - 0.01 15.3 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.1 OAJ26288.1 - 0.01 15.8 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.16 OAJ26288.1 - 0.12 12.0 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family DUF619 PF04768.8 OAJ26289.1 - 4.6e-43 146.5 0.0 7.8e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) AA_kinase PF00696.23 OAJ26289.1 - 1.8e-22 80.0 0.0 3.9e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.19 OAJ26289.1 - 7.3e-22 77.9 0.0 1.7e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 OAJ26289.1 - 0.012 16.1 0.0 0.15 12.5 0.0 2.9 3 1 1 4 4 4 0 Oxidoreductase family, NAD-binding Rossmann fold Arm PF00514.18 OAJ26289.1 - 0.036 13.9 0.2 0.41 10.5 0.0 2.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DapB_N PF01113.15 OAJ26289.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Acetyltransf_8 PF13523.1 OAJ26291.1 - 4.6e-39 133.7 0.1 6.3e-39 133.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 OAJ26291.1 - 0.077 13.1 0.1 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1917 PF08939.5 OAJ26292.1 - 2.7e-11 43.7 1.6 2.7e-11 43.7 1.1 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF1917) Serglycin PF04360.7 OAJ26292.1 - 0.65 9.7 5.5 1.6 8.4 3.8 1.8 1 1 0 1 1 1 0 Serglycin DUF1767 PF08585.7 OAJ26293.1 - 2.2e-12 47.0 0.0 3.8e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) IMPDH PF00478.20 OAJ26294.1 - 6.3e-137 456.1 0.0 3e-135 450.6 0.0 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 OAJ26294.1 - 1.2e-20 73.0 0.0 1.5e-09 37.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 OAJ26294.1 - 1.1e-10 41.1 11.9 2e-07 30.4 7.2 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 OAJ26294.1 - 1.3e-08 34.0 4.1 3.7e-08 32.6 2.8 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 OAJ26294.1 - 8.2e-08 31.7 2.8 8.2e-07 28.5 2.0 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 OAJ26294.1 - 1.1e-05 24.6 1.6 1.8e-05 23.9 1.1 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Dus PF01207.12 OAJ26294.1 - 0.14 11.0 0.6 0.62 8.8 0.0 2.0 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Phage_integrase PF00589.17 OAJ26298.1 - 0.0003 20.4 0.0 0.00045 19.9 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family ABC_membrane PF00664.18 OAJ26300.1 - 9.7e-67 225.2 21.2 8.7e-37 127.0 2.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ26300.1 - 1.3e-60 203.6 0.0 1.2e-32 113.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAJ26300.1 - 1e-10 41.2 0.2 0.0026 17.0 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAJ26300.1 - 5.3e-10 39.7 0.2 0.00028 20.9 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA_17 PF13207.1 OAJ26300.1 - 4.9e-08 33.8 0.3 0.00082 20.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 OAJ26300.1 - 4.2e-07 29.3 2.5 0.013 15.0 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 OAJ26300.1 - 3.7e-06 27.2 0.1 0.093 13.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 OAJ26300.1 - 9.7e-06 25.6 9.4 0.00029 20.8 0.3 4.1 2 2 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 OAJ26300.1 - 4e-05 22.8 0.1 0.022 13.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 OAJ26300.1 - 6.7e-05 22.3 0.1 0.49 9.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 OAJ26300.1 - 0.00023 21.3 2.1 0.18 11.9 0.5 3.7 2 1 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 OAJ26300.1 - 0.0005 18.7 1.4 0.24 9.9 0.0 3.0 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_5 PF07728.9 OAJ26300.1 - 0.003 17.2 0.6 1.7 8.3 0.0 4.0 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 OAJ26300.1 - 0.0054 16.2 7.8 4.1 6.7 0.2 4.5 5 0 0 5 5 5 1 AAA-like domain ATP-synt_ab PF00006.20 OAJ26300.1 - 0.0074 15.8 0.4 0.86 9.0 0.1 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 OAJ26300.1 - 0.017 15.0 0.9 5.9 6.7 0.0 3.7 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 OAJ26300.1 - 0.023 14.1 0.2 8.3 5.8 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 OAJ26300.1 - 0.025 14.4 3.5 1.1 9.0 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 APS_kinase PF01583.15 OAJ26300.1 - 0.035 13.7 0.1 2.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase Sigma54_activat PF00158.21 OAJ26300.1 - 0.039 13.4 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.1 OAJ26300.1 - 0.048 13.9 0.9 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 OAJ26300.1 - 0.05 13.7 0.2 3.2 7.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 OAJ26300.1 - 0.088 12.7 0.0 2.2 8.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 OAJ26300.1 - 0.11 12.1 1.1 4.1 7.0 0.0 3.3 3 0 0 3 3 2 0 NACHT domain KaiC PF06745.8 OAJ26300.1 - 0.17 10.9 2.7 4.2 6.4 0.1 2.7 3 0 0 3 3 2 0 KaiC G-alpha PF00503.15 OAJ26300.1 - 0.19 10.3 0.7 0.77 8.3 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit Miro PF08477.8 OAJ26300.1 - 0.21 12.0 0.2 15 6.0 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 OAJ26300.1 - 0.21 11.2 0.3 16 5.2 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 OAJ26300.1 - 0.29 10.6 0.9 2.2 7.8 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 OAJ26300.1 - 0.71 9.8 8.6 0.35 10.8 0.2 3.5 4 0 0 4 4 3 0 AAA domain Dynactin_p62 PF05502.8 OAJ26301.1 - 1e-67 228.9 8.7 9.3e-46 156.5 7.7 2.2 2 0 0 2 2 2 2 Dynactin p62 family FAT PF02259.18 OAJ26302.1 - 2.2e-91 306.4 1.7 4.2e-84 282.5 0.1 2.6 1 1 1 2 2 2 2 FAT domain PI3_PI4_kinase PF00454.22 OAJ26302.1 - 9.8e-55 185.5 0.6 1.8e-54 184.6 0.4 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 OAJ26302.1 - 3.8e-47 160.1 0.0 3.5e-44 150.5 0.0 3.6 2 1 1 3 3 3 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 OAJ26302.1 - 4.4e-24 84.4 0.7 1.8e-23 82.5 0.2 2.4 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 OAJ26302.1 - 3.3e-15 56.1 30.2 0.00097 19.3 0.1 10.8 5 3 5 10 10 10 6 HEAT repeats HEAT PF02985.17 OAJ26302.1 - 3.3e-14 51.5 16.8 0.07 13.2 0.1 10.5 10 0 0 10 10 10 4 HEAT repeat FATC PF02260.15 OAJ26302.1 - 2.4e-09 36.4 0.1 5.8e-09 35.2 0.1 1.7 1 0 0 1 1 1 1 FATC domain Cnd1 PF12717.2 OAJ26302.1 - 0.00024 21.0 3.6 0.74 9.6 0.1 5.6 5 1 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 OAJ26302.1 - 0.001 17.4 4.9 0.82 7.9 0.5 4.3 2 1 1 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 OAJ26302.1 - 0.018 15.4 0.1 15 6.0 0.0 5.3 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region VHS PF00790.14 OAJ26302.1 - 0.025 14.2 0.0 18 4.9 0.0 3.7 4 0 0 4 4 4 0 VHS domain HEAT_EZ PF13513.1 OAJ26302.1 - 0.043 14.3 0.2 0.043 14.3 0.1 13.2 12 3 6 18 18 17 0 HEAT-like repeat ACPS PF01648.15 OAJ26303.1 - 2.8e-19 69.0 0.2 6e-19 67.9 0.2 1.6 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily zf-met2 PF12907.2 OAJ26305.1 - 3.2e-13 49.4 0.9 4.7e-13 48.8 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 OAJ26305.1 - 3.9e-09 37.0 9.6 3.9e-09 37.0 6.6 1.8 2 0 0 2 2 2 1 4F5 protein family Eapp_C PF10238.4 OAJ26305.1 - 0.066 13.1 0.8 0.083 12.7 0.5 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein zinc_ribbon_4 PF13717.1 OAJ26305.1 - 0.072 12.7 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 OAJ26305.1 - 0.084 13.2 0.4 11 6.5 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zinc_ribbon_5 PF13719.1 OAJ26305.1 - 0.089 12.3 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain TPT PF03151.11 OAJ26306.1 - 7.9e-21 74.3 13.0 7.9e-21 74.3 9.0 2.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 OAJ26306.1 - 0.0055 16.7 7.5 0.0055 16.7 5.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family IMS PF00817.15 OAJ26307.1 - 9.6e-38 129.3 0.1 3.2e-37 127.5 0.1 1.9 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 OAJ26307.1 - 4.3e-06 26.6 0.0 9.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF1610 PF07754.6 OAJ26307.1 - 0.092 12.8 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) IMS_HHH PF11798.3 OAJ26307.1 - 0.16 12.0 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif Porphobil_deam PF01379.15 OAJ26308.1 - 1.5e-67 226.6 0.0 3.6e-63 212.3 0.0 2.5 3 0 0 3 3 3 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 OAJ26308.1 - 1e-12 47.9 0.0 6.7e-08 32.5 0.0 2.7 2 0 0 2 2 2 2 Porphobilinogen deaminase, C-terminal domain Profilin PF00235.14 OAJ26308.1 - 0.21 11.6 0.0 0.47 10.5 0.0 1.5 1 0 0 1 1 1 0 Profilin DAHP_synth_1 PF00793.15 OAJ26309.1 - 0.13 10.8 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 DAHP synthetase I family Med3 PF11593.3 OAJ26309.1 - 0.41 9.8 5.9 0.58 9.3 4.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_S2 PF00318.15 OAJ26310.1 - 4.2e-46 156.8 0.0 5e-24 84.6 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Gloverin PF10793.4 OAJ26310.1 - 1.9 8.0 4.5 2.7 7.6 1.6 2.1 2 1 0 2 2 2 0 Gloverin-like protein Hepar_II_III PF07940.8 OAJ26311.1 - 1.7e-05 24.7 1.8 6.6e-05 22.7 1.3 2.1 1 1 0 1 1 1 1 Heparinase II/III-like protein Avl9 PF09794.4 OAJ26312.1 - 7.8e-129 429.4 0.0 9.9e-129 429.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 OAJ26312.1 - 5.2e-07 29.2 0.0 0.033 13.4 0.0 3.0 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 OAJ26312.1 - 2e-06 27.4 0.0 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis Afi1 PF07792.7 OAJ26312.1 - 0.003 17.5 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking FAT PF02259.18 OAJ26313.1 - 3.1e-110 368.4 2.4 3.1e-110 368.4 1.7 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 OAJ26313.1 - 4.3e-52 176.9 0.4 7.1e-52 176.2 0.3 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 OAJ26313.1 - 6.9e-46 156.1 0.0 1.4e-43 148.6 0.0 3.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 OAJ26313.1 - 5.6e-38 129.0 3.2 1.1e-37 128.1 0.8 2.8 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 OAJ26313.1 - 2.3e-18 66.2 17.7 0.00051 20.2 0.0 9.6 5 3 3 9 9 9 3 HEAT repeats HEAT PF02985.17 OAJ26313.1 - 1.4e-11 43.4 17.0 1.1 9.4 0.1 11.7 12 0 0 12 12 12 4 HEAT repeat FATC PF02260.15 OAJ26313.1 - 4.6e-10 38.7 0.0 1.1e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 FATC domain Cnd1 PF12717.2 OAJ26313.1 - 1.7e-05 24.7 2.7 0.0028 17.5 0.0 5.3 5 1 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 OAJ26313.1 - 0.00032 21.0 38.0 0.26 11.8 0.3 12.4 9 3 8 17 17 15 3 HEAT-like repeat UME PF08064.8 OAJ26313.1 - 0.0014 18.5 1.0 5.3 7.0 0.0 4.5 4 1 1 5 5 5 1 UME (NUC010) domain IBN_N PF03810.14 OAJ26313.1 - 0.0077 16.1 1.4 2.4 8.1 0.0 5.1 6 0 0 6 6 5 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 OAJ26313.1 - 0.0087 14.4 6.9 0.068 11.4 0.1 4.6 4 1 0 5 5 5 1 Adaptin N terminal region Proteasom_PSMB PF10508.4 OAJ26313.1 - 0.011 14.1 0.2 0.082 11.1 0.1 2.3 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit FdhE PF04216.7 OAJ26313.1 - 0.027 14.2 4.1 0.36 10.5 0.1 3.8 3 0 0 3 3 3 0 Protein involved in formate dehydrogenase formation TPR_11 PF13414.1 OAJ26313.1 - 0.99 9.0 8.0 1.3 8.7 0.0 4.9 5 0 0 5 5 5 0 TPR repeat Lipase_GDSL PF00657.17 OAJ26314.1 - 5.7e-15 55.7 0.0 7.3e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 OAJ26314.1 - 2.9e-06 27.5 0.1 4.7e-06 26.8 0.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GTP_EFTU PF00009.22 OAJ26315.1 - 5.5e-45 153.1 0.0 7.4e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 OAJ26315.1 - 2.5e-09 37.2 0.1 6.8e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 OAJ26315.1 - 3.5e-07 30.1 0.0 8.6e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 OAJ26315.1 - 6.3e-07 29.4 0.3 1.7e-06 28.0 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 OAJ26315.1 - 1.6e-06 27.6 0.3 3.7e-06 26.4 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SRPRB PF09439.5 OAJ26315.1 - 0.0007 18.8 0.0 0.59 9.3 0.0 2.2 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Miro PF08477.8 OAJ26315.1 - 0.0076 16.7 0.0 0.042 14.3 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein Septin PF00735.13 OAJ26315.1 - 0.023 13.7 0.0 0.081 11.9 0.0 1.8 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.18 OAJ26315.1 - 0.033 14.0 0.0 0.69 9.7 0.0 2.3 1 1 1 2 2 2 0 Dynamin family cobW PF02492.14 OAJ26315.1 - 0.04 13.3 0.0 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 OAJ26315.1 - 0.049 13.3 0.1 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 OAJ26315.1 - 0.067 12.4 0.0 4 6.6 0.0 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B SMC_N PF02463.14 OAJ26316.1 - 6.6e-61 205.3 0.0 2.7e-60 203.3 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 OAJ26316.1 - 4.5e-28 97.6 1.4 2.3e-27 95.3 0.1 2.9 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 OAJ26316.1 - 7.2e-17 62.2 0.7 1.1e-07 32.0 0.0 3.8 4 0 0 4 4 4 3 AAA domain AAA_23 PF13476.1 OAJ26316.1 - 3.5e-15 56.8 0.2 3.5e-15 56.8 0.2 6.4 2 2 2 5 5 5 1 AAA domain AAA_29 PF13555.1 OAJ26316.1 - 3.2e-08 32.9 0.3 1.2e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.1 OAJ26316.1 - 0.00023 20.3 0.0 0.00073 18.7 0.0 4.7 5 0 0 5 5 5 2 AAA ATPase domain SbcCD_C PF13558.1 OAJ26316.1 - 0.00047 20.0 0.0 0.0021 17.9 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Reo_sigmaC PF04582.7 OAJ26316.1 - 0.0057 15.8 27.2 0.11 11.6 0.7 4.4 2 2 2 4 4 4 3 Reovirus sigma C capsid protein ABC_tran PF00005.22 OAJ26316.1 - 0.061 13.6 0.0 0.061 13.6 0.0 6.0 4 3 0 4 4 4 0 ABC transporter AAA_17 PF13207.1 OAJ26316.1 - 0.71 10.7 0.0 0.71 10.7 0.0 3.7 3 2 1 4 4 4 0 AAA domain Rhodanese PF00581.15 OAJ26317.1 - 3.5e-16 59.5 0.0 6.8e-09 36.0 0.0 3.2 2 1 0 2 2 2 2 Rhodanese-like domain HBS1_N PF08938.5 OAJ26318.1 - 2.3e-09 37.2 0.9 5.6e-09 35.9 0.6 1.6 1 0 0 1 1 1 1 HBS1 N-terminus DUF572 PF04502.8 OAJ26318.1 - 0.058 12.6 5.5 0.08 12.1 3.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) RNA_pol_Rbc25 PF08292.7 OAJ26320.1 - 1.9e-28 99.0 0.0 1.9e-27 95.8 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 OAJ26320.1 - 5.7e-16 58.3 0.0 1.2e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 OAJ26320.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.8 1 1 0 1 1 1 0 S1 RNA binding domain Fip1 PF05182.8 OAJ26321.1 - 8e-19 66.6 0.7 1.4e-18 65.8 0.5 1.4 1 0 0 1 1 1 1 Fip1 motif DUF1777 PF08648.7 OAJ26321.1 - 0.0022 17.7 5.5 0.0022 17.7 3.8 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF1777) COPI_C PF06957.6 OAJ26321.1 - 2.2 6.7 11.0 5.8 5.3 7.6 1.6 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus COG2 PF06148.6 OAJ26322.1 - 1.9e-12 47.2 0.8 5.6e-12 45.6 0.6 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 OAJ26322.1 - 0.0022 18.0 0.0 0.035 14.2 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3510) BAR PF03114.13 OAJ26322.1 - 0.0092 15.5 0.4 3.1 7.2 0.1 2.6 2 0 0 2 2 2 2 BAR domain Ribosomal_S19e PF01090.14 OAJ26323.1 - 3e-52 175.7 0.0 3.5e-52 175.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e TFIIA PF03153.8 OAJ26323.1 - 0.013 15.3 8.5 0.012 15.5 5.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RXT2_N PF08595.6 OAJ26323.1 - 0.2 11.4 7.2 0.23 11.2 5.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.7 OAJ26323.1 - 0.25 11.0 13.5 0.28 10.8 9.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 OAJ26323.1 - 0.26 10.5 13.9 0.33 10.1 9.6 1.2 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.7 OAJ26323.1 - 3.6 6.7 14.5 4.1 6.5 10.1 1.1 1 0 0 1 1 1 0 NOA36 protein MIP PF00230.15 OAJ26325.1 - 7.2e-17 61.6 2.1 8.3e-17 61.4 1.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF3925 PF13063.1 OAJ26325.1 - 0.036 14.0 2.3 0.08 12.9 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) Ribosomal_S7 PF00177.16 OAJ26326.1 - 2.2e-28 98.6 0.0 5.2e-28 97.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e Med3 PF11593.3 OAJ26326.1 - 3.6 6.7 8.5 5.4 6.1 5.9 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Nefa_Nip30_N PF10187.4 OAJ26327.1 - 8.5e-26 90.1 7.9 1.4e-25 89.4 5.5 1.4 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 zf-C4H2 PF10146.4 OAJ26327.1 - 0.087 12.8 1.2 0.14 12.1 0.8 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein TFCD_C PF12612.3 OAJ26328.1 - 3.8e-29 101.5 0.0 2.7e-28 98.7 0.0 2.6 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 OAJ26328.1 - 0.0044 16.9 0.0 0.0044 16.9 0.0 7.1 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.2 OAJ26328.1 - 0.0068 16.2 0.1 0.97 9.2 0.0 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 OAJ26328.1 - 0.012 16.1 0.1 0.012 16.1 0.0 7.4 8 1 1 9 9 9 0 HEAT-like repeat B56 PF01603.15 OAJ26328.1 - 0.022 13.3 0.1 0.28 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) Vac14_Fab1_bd PF12755.2 OAJ26328.1 - 0.023 15.0 0.1 0.24 11.7 0.0 2.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Peptidase_M24 PF00557.19 OAJ26329.1 - 2.3e-20 73.0 0.0 3e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 HLH PF00010.21 OAJ26330.1 - 8.3e-15 54.2 0.2 1.5e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Zip PF02535.17 OAJ26330.1 - 0.27 10.1 3.5 0.35 9.8 2.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 OAJ26330.1 - 0.36 9.0 3.8 0.53 8.5 2.6 1.3 1 0 0 1 1 1 0 Transmembrane protein GPP34 PF05719.6 OAJ26331.1 - 7.2e-62 209.1 0.0 1.2e-61 208.3 0.0 1.4 1 1 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Ribosomal_L18e PF00828.14 OAJ26332.1 - 2.2e-34 118.6 0.6 2.8e-34 118.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DUF829 PF05705.9 OAJ26333.1 - 8.7e-25 87.7 0.1 2.4e-15 56.9 0.0 3.4 3 1 0 3 3 3 3 Eukaryotic protein of unknown function (DUF829) ECH PF00378.15 OAJ26334.1 - 4.9e-76 255.0 3.4 6.2e-76 254.7 2.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 OAJ26334.1 - 0.00013 21.8 2.1 0.0021 17.8 0.0 2.3 2 0 0 2 2 2 1 Peptidase family S49 SDH_sah PF01972.11 OAJ26334.1 - 0.081 11.6 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase ECH_C PF13766.1 OAJ26334.1 - 0.1 12.7 0.2 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region DnaJ_CXXCXGXG PF00684.14 OAJ26343.1 - 1.7e-15 56.7 10.5 2.6e-15 56.2 7.2 1.2 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 OAJ26343.1 - 0.11 12.1 5.0 0.35 10.5 2.0 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 OAJ26343.1 - 0.32 10.8 6.6 0.65 9.8 4.6 1.6 1 1 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.1 OAJ26343.1 - 0.41 10.9 2.5 1.5 9.2 1.7 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar Cytochrome_C7 PF14522.1 OAJ26343.1 - 0.7 9.5 7.3 3.6 7.2 5.1 2.0 1 1 1 2 2 2 0 Cytochrome c7 Cytochrom_c3_2 PF14537.1 OAJ26343.1 - 2.2 8.6 9.1 1 9.7 3.4 1.9 1 1 1 2 2 2 0 Cytochrome c3 A2L_zn_ribbon PF08792.5 OAJ26343.1 - 5.5 6.5 8.0 10 5.7 0.4 3.1 2 1 1 3 3 3 0 A2L zinc ribbon domain zf-TFIIB PF13453.1 OAJ26343.1 - 5.8 6.1 9.7 8.6 5.6 0.2 3.3 3 0 0 3 3 3 0 Transcription factor zinc-finger Spc97_Spc98 PF04130.8 OAJ26344.1 - 2e-112 376.2 0.0 2.6e-112 375.9 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Pkinase PF00069.20 OAJ26345.1 - 7.1e-47 159.7 0.0 1.6e-44 152.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ26345.1 - 2.7e-16 59.4 0.0 7.6e-15 54.6 0.0 2.7 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ26345.1 - 0.00088 18.3 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ26345.1 - 0.0061 15.6 0.0 0.0097 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 OAJ26345.1 - 0.71 9.1 0.0 1.3 8.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Nucleoplasmin PF03066.10 OAJ26345.1 - 0.77 9.2 9.6 2.6 7.5 0.3 3.4 4 0 0 4 4 4 0 Nucleoplasmin PBP1_TM PF14812.1 OAJ26345.1 - 1.4 9.2 9.0 8.7 6.7 1.7 3.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Med6 PF04934.9 OAJ26346.1 - 3.6e-42 143.2 0.0 4.2e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component Nucleoplasmin PF03066.10 OAJ26346.1 - 0.005 16.3 0.3 0.0058 16.1 0.2 1.3 1 0 0 1 1 1 1 Nucleoplasmin Mpp10 PF04006.7 OAJ26346.1 - 0.037 12.4 1.1 0.048 12.0 0.8 1.1 1 0 0 1 1 1 0 Mpp10 protein Sigma70_ner PF04546.8 OAJ26346.1 - 0.13 11.8 1.4 0.18 11.3 0.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 OAJ26346.1 - 3.2 8.0 11.9 4.9 7.4 7.5 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2457 PF10446.4 OAJ26346.1 - 3.7 6.1 12.1 5.1 5.7 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Rad10 PF03834.9 OAJ26347.1 - 1.9e-31 107.5 0.1 3.5e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 OAJ26347.1 - 9.4e-08 32.1 0.0 2.4e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 OAJ26347.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF2360 PF10152.4 OAJ26347.1 - 0.04 14.1 0.3 0.076 13.2 0.2 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) K_channel_TID PF07941.6 OAJ26347.1 - 0.11 12.7 2.0 0.26 11.5 1.4 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Apc3 PF12895.2 OAJ26347.1 - 0.13 12.3 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Ras PF00071.17 OAJ26348.1 - 1.4e-47 161.0 0.0 1.6e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ26348.1 - 3.4e-17 63.0 0.1 6.2e-17 62.1 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 OAJ26348.1 - 1.9e-06 27.2 0.0 2.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ26348.1 - 2.2e-05 24.0 0.0 4.8e-05 22.8 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ26348.1 - 0.01 15.7 0.1 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.1 OAJ26348.1 - 0.025 13.9 0.0 0.032 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.11 OAJ26348.1 - 0.049 12.7 0.1 0.075 12.1 0.1 1.4 1 0 0 1 1 1 0 AIG1 family DnaJ PF00226.26 OAJ26349.1 - 8.9e-21 73.3 4.9 1.4e-20 72.7 3.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 OAJ26349.1 - 1.8e-16 59.9 16.9 2.9e-16 59.2 11.7 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 OAJ26349.1 - 0.012 15.2 7.8 0.98 9.1 2.0 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family TMEM95 PF15203.1 OAJ26349.1 - 0.14 11.6 6.0 0.13 11.6 1.3 2.1 1 1 1 2 2 2 0 TMEM95 family Cytochrom_c3_2 PF14537.1 OAJ26349.1 - 0.83 10.0 12.5 3.1 8.1 3.4 2.3 1 1 1 2 2 2 0 Cytochrome c3 DZR PF12773.2 OAJ26349.1 - 1.3 8.8 10.7 8.2 6.3 7.7 2.0 1 1 1 2 2 2 0 Double zinc ribbon Acyl_transf_3 PF01757.17 OAJ26350.1 - 2.6e-05 23.2 35.0 3.8e-05 22.6 24.3 1.2 1 0 0 1 1 1 1 Acyltransferase family PAS_9 PF13426.1 OAJ26351.1 - 2.7e-21 75.9 0.0 1.9e-12 47.4 0.0 3.0 3 0 0 3 3 3 2 PAS domain PAS PF00989.19 OAJ26351.1 - 5.8e-13 48.6 0.6 4.6e-08 32.8 0.0 3.9 4 1 0 4 4 4 2 PAS fold PAS_3 PF08447.6 OAJ26351.1 - 1.2e-11 44.4 0.0 4.7e-06 26.5 0.0 4.3 4 0 0 4 4 4 2 PAS fold PAS_4 PF08448.5 OAJ26351.1 - 1.1e-06 28.6 0.0 0.00025 21.0 0.0 3.7 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.1 OAJ26351.1 - 7.8e-05 22.3 0.0 0.025 14.4 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.1 OAJ26351.1 - 0.005 16.7 0.6 0.04 13.8 0.0 2.7 3 0 0 3 3 3 1 PAS domain Usp PF00582.21 OAJ26353.1 - 3.9e-13 49.7 1.5 3.9e-13 49.7 1.1 2.2 2 1 0 2 2 2 1 Universal stress protein family DNA_pol_viral_N PF00242.12 OAJ26353.1 - 2.1 7.2 11.9 1.1 8.2 6.4 1.8 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 OAJ26353.1 - 6.4 4.9 16.8 12 4.0 11.6 1.4 1 0 0 1 1 1 0 Transmembrane protein AAA_33 PF13671.1 OAJ26354.1 - 3.4e-13 49.6 0.1 5.1e-12 45.8 0.0 2.6 2 1 0 2 2 1 1 AAA domain Y_phosphatase PF00102.22 OAJ26354.1 - 1.1e-06 28.1 0.0 4.7e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase RNA_ligase PF09414.5 OAJ26354.1 - 0.00023 20.9 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 RNA ligase AAA_17 PF13207.1 OAJ26354.1 - 0.00085 20.1 0.7 0.014 16.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain Y_phosphatase3 PF13350.1 OAJ26354.1 - 0.0012 19.1 1.3 0.0087 16.3 0.4 2.3 1 1 1 2 2 2 1 Tyrosine phosphatase family AAA_25 PF13481.1 OAJ26354.1 - 0.0018 17.7 0.1 0.042 13.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain DSPc PF00782.15 OAJ26354.1 - 0.0036 16.8 0.0 0.0078 15.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Zeta_toxin PF06414.7 OAJ26354.1 - 0.004 16.2 0.0 0.0092 15.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 OAJ26354.1 - 0.0064 16.8 0.1 2.5 8.3 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 OAJ26354.1 - 0.0076 16.3 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAJ26354.1 - 0.0087 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein PTPlike_phytase PF14566.1 OAJ26354.1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate KTI12 PF08433.5 OAJ26354.1 - 0.039 13.1 0.3 0.76 8.9 0.2 2.2 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Plus-3 PF03126.13 OAJ26354.1 - 0.096 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Plus-3 domain AAA_5 PF07728.9 OAJ26354.1 - 0.11 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 OAJ26354.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 OAJ26354.1 - 0.21 11.5 0.0 0.71 9.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Peptidase_M1 PF01433.15 OAJ26355.1 - 3.2e-100 335.9 0.0 5.6e-64 216.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 OAJ26355.1 - 2.2e-56 191.4 0.1 4e-56 190.6 0.1 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 OAJ26355.1 - 1.3e-14 54.3 0.0 2.7e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Nnf1 PF03980.9 OAJ26357.1 - 2.7e-06 27.3 4.9 2.7e-06 27.3 3.4 1.8 2 0 0 2 2 2 1 Nnf1 IFT57 PF10498.4 OAJ26357.1 - 0.00031 19.5 3.6 0.00054 18.8 2.5 1.4 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DASH_Spc34 PF08657.5 OAJ26357.1 - 0.0047 16.6 1.9 0.0047 16.6 1.3 2.1 3 0 0 3 3 3 1 DASH complex subunit Spc34 PrgH PF09480.5 OAJ26357.1 - 0.023 13.5 0.7 0.035 12.9 0.5 1.3 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) Atg14 PF10186.4 OAJ26357.1 - 0.97 8.3 9.8 1.7 7.5 6.8 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Rbsn PF11464.3 OAJ26357.1 - 1.3 8.6 6.0 0.44 10.1 0.4 2.8 4 0 0 4 4 4 0 Rabenosyn Rab binding domain DUF972 PF06156.8 OAJ26357.1 - 5.4 7.4 12.4 1.5 9.1 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 OAJ26357.1 - 6.2 6.4 8.3 2.5 7.7 3.8 1.9 2 0 0 2 2 2 0 Mnd1 family DinB PF05163.7 OAJ26357.1 - 8.3 6.0 8.2 6.4 6.4 0.1 2.3 1 1 0 2 2 2 0 DinB family Tht1 PF04163.7 OAJ26358.1 - 0.042 12.2 0.1 0.042 12.2 0.1 1.8 1 1 1 2 2 2 0 Tht1-like nuclear fusion protein MRP-S23 PF10484.4 OAJ26358.1 - 0.58 10.0 3.9 1.5 8.7 0.8 2.6 2 1 1 3 3 3 0 Mitochondrial ribosomal protein S23 GrpE PF01025.14 OAJ26358.1 - 0.96 8.9 12.4 0.061 12.8 2.0 2.3 2 0 0 2 2 2 0 GrpE ApoLp-III PF07464.6 OAJ26358.1 - 1.4 8.9 11.0 0.26 11.3 3.2 2.4 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Ferric_reduct PF01794.14 OAJ26359.1 - 2.4e-16 59.9 10.9 2.4e-16 59.9 7.6 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 OAJ26359.1 - 4.5e-13 49.3 0.0 8.8e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 OAJ26359.1 - 9.5e-07 28.6 0.0 6e-05 22.8 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 OAJ26359.1 - 0.012 16.1 0.0 0.11 13.0 0.0 2.4 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4405 PF14358.1 OAJ26359.1 - 0.056 13.5 7.8 2.4 8.3 0.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) RF-1 PF00472.15 OAJ26360.1 - 9e-38 128.5 1.8 2.1e-37 127.3 1.2 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 OAJ26360.1 - 6.5e-33 112.8 0.0 2.1e-32 111.2 0.0 1.9 1 0 0 1 1 1 1 PCRF domain DUF2418 PF10332.4 OAJ26361.1 - 1.1e-18 67.3 1.0 1.1e-18 67.3 0.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Myc_N PF01056.13 OAJ26361.1 - 0.0024 17.1 3.0 0.0024 17.1 2.0 1.7 2 0 0 2 2 2 1 Myc amino-terminal region Nucleo_P87 PF07267.6 OAJ26361.1 - 0.041 12.5 1.1 0.058 12.0 0.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nucleoplasmin PF03066.10 OAJ26361.1 - 0.099 12.1 13.8 0.17 11.3 9.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 OAJ26361.1 - 0.16 9.8 7.4 0.21 9.4 5.1 1.1 1 0 0 1 1 1 0 Nop14-like family Cytomega_UL84 PF06284.6 OAJ26361.1 - 0.64 8.3 3.3 1 7.7 2.3 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF2457 PF10446.4 OAJ26361.1 - 0.8 8.3 11.3 1.9 7.1 7.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) VID27 PF08553.5 OAJ26361.1 - 1.1 7.4 4.8 1.5 6.9 3.3 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Daxx PF03344.10 OAJ26361.1 - 4.1 5.7 11.9 7.4 4.9 8.2 1.3 1 0 0 1 1 1 0 Daxx Family PBP1_TM PF14812.1 OAJ26361.1 - 7.3 6.9 17.2 1.4 9.2 9.0 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RasGAP PF00616.14 OAJ26362.1 - 2.2e-55 187.3 0.0 5.3e-55 186.1 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 OAJ26362.1 - 1.1e-39 135.3 0.2 3.1e-39 133.9 0.1 1.8 1 0 0 1 1 1 1 RasGAP C-terminus DUF972 PF06156.8 OAJ26362.1 - 0.011 16.0 0.6 4.8 7.5 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Ribosomal_L19 PF01245.15 OAJ26363.1 - 2.4e-22 78.8 0.1 3.6e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 ABC2_membrane PF01061.19 OAJ26364.1 - 5.6e-32 110.6 17.5 5.6e-32 110.6 12.1 1.9 3 0 0 3 3 1 1 ABC-2 type transporter ABC_tran PF00005.22 OAJ26364.1 - 3.9e-26 91.9 0.0 6.2e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 OAJ26364.1 - 2.7e-08 34.1 0.0 0.00028 20.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAJ26364.1 - 1.7e-06 27.6 0.0 8.2e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ26364.1 - 3.5e-05 23.8 0.3 7.9e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ26364.1 - 0.00027 21.0 0.0 0.00084 19.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ26364.1 - 0.00057 19.5 0.3 0.0022 17.7 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 OAJ26364.1 - 0.001 18.5 0.2 0.003 17.0 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 OAJ26364.1 - 0.0012 18.0 0.0 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAJ26364.1 - 0.0024 18.7 0.0 0.0045 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 OAJ26364.1 - 0.0043 16.7 0.0 0.0089 15.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.1 OAJ26364.1 - 0.0043 17.0 0.0 0.0075 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 OAJ26364.1 - 0.0073 16.1 0.0 0.067 13.1 0.0 2.6 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 OAJ26364.1 - 0.02 14.0 0.0 0.044 13.0 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAJ26364.1 - 0.039 14.2 0.2 0.061 13.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 OAJ26364.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 OAJ26364.1 - 0.051 13.7 0.0 0.86 9.8 0.0 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 OAJ26364.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAJ26364.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 OAJ26364.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 OAJ26364.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.12 OAJ26364.1 - 0.2 11.0 0.3 1.3 8.4 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.1 OAJ26364.1 - 0.21 11.1 0.3 0.37 10.3 0.2 1.2 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 OAJ26364.1 - 0.37 10.4 0.0 0.67 9.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase hEGF PF12661.2 OAJ26364.1 - 4.8 7.4 7.9 24 5.3 2.2 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF Zn_clus PF00172.13 OAJ26365.1 - 1.1e-06 28.4 9.6 1.1e-06 28.4 6.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRAP_alpha PF03896.11 OAJ26365.1 - 9.7 5.0 6.2 23 3.8 4.3 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Proteasome PF00227.21 OAJ26366.1 - 5.8e-46 156.1 0.4 5.1e-43 146.5 0.1 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 OAJ26366.1 - 3.4e-14 51.8 0.1 6.3e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Mic1 PF07035.7 OAJ26370.1 - 0.15 11.3 9.8 0.16 11.3 1.0 2.2 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like Gly_radical PF01228.16 OAJ26370.1 - 2.7 8.4 5.6 1.7 8.9 0.8 2.2 2 0 0 2 2 2 0 Glycine radical DUF1768 PF08719.6 OAJ26371.1 - 5.9e-20 71.5 0.0 9.3e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Not3 PF04065.10 OAJ26372.1 - 4.7e-95 317.2 18.7 4.7e-95 317.2 12.9 2.2 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 OAJ26372.1 - 9.3e-46 155.0 11.0 9.3e-46 155.0 7.6 3.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Mg_trans_NIPA PF05653.9 OAJ26373.1 - 6.7e-08 31.8 0.5 8.7e-08 31.4 0.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA GP11 PF08677.5 OAJ26374.1 - 0.1 11.7 0.3 0.15 11.1 0.2 1.2 1 0 0 1 1 1 0 GP11 baseplate wedge protein RNA_pol_Rpc82 PF05645.8 OAJ26383.1 - 4.7e-09 36.1 0.0 3.5e-08 33.3 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.12 OAJ26383.1 - 9.8e-05 21.8 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit Ureide_permease PF07168.6 OAJ26384.1 - 0.15 10.6 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Ureide permease QueF_N PF14819.1 OAJ26385.1 - 4e-06 26.8 0.4 0.71 9.9 0.1 3.4 3 0 0 3 3 3 3 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term DUF1018 PF06252.7 OAJ26385.1 - 0.089 13.3 0.3 65 4.0 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1018) PNP_UDP_1 PF01048.15 OAJ26386.1 - 4.1e-30 104.4 5.3 4.2e-29 101.1 3.7 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily Guanylate_kin PF00625.16 OAJ26387.1 - 8.5e-55 185.0 0.0 1e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 OAJ26387.1 - 5.7e-08 32.9 0.3 4.2e-07 30.1 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ26387.1 - 4.4e-07 30.1 0.0 1.1e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 OAJ26387.1 - 1.4e-05 24.3 0.0 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAJ26387.1 - 5e-05 24.1 0.0 8e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ26387.1 - 0.00013 22.2 0.0 0.00035 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 OAJ26387.1 - 0.00018 21.0 0.0 0.0011 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA-like domain AAA_33 PF13671.1 OAJ26387.1 - 0.00021 21.2 0.1 0.00049 19.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 OAJ26387.1 - 0.00028 21.2 0.0 0.00045 20.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Arch_ATPase PF01637.13 OAJ26387.1 - 0.00052 19.7 0.0 0.00074 19.2 0.0 1.4 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 OAJ26387.1 - 0.00083 19.2 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 OAJ26387.1 - 0.0039 16.8 0.0 0.0081 15.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 OAJ26387.1 - 0.0042 17.0 0.0 0.0066 16.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 OAJ26387.1 - 0.0052 16.9 0.0 0.0083 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA helicase MobB PF03205.9 OAJ26387.1 - 0.0056 16.3 0.0 0.011 15.4 0.0 1.5 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 OAJ26387.1 - 0.0064 16.9 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein NTPase_1 PF03266.10 OAJ26387.1 - 0.0069 16.1 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 NTPase AAA_29 PF13555.1 OAJ26387.1 - 0.0095 15.4 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 OAJ26387.1 - 0.014 15.3 0.2 0.052 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 OAJ26387.1 - 0.043 12.7 0.0 0.088 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PTS_IIB PF02302.12 OAJ26387.1 - 0.047 14.1 0.0 0.34 11.4 0.0 2.3 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit Septin PF00735.13 OAJ26387.1 - 0.047 12.6 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_30 PF13604.1 OAJ26387.1 - 0.048 13.2 0.0 0.077 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 OAJ26387.1 - 0.052 13.7 0.0 0.078 13.1 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAJ26387.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AFG1_ATPase PF03969.11 OAJ26387.1 - 0.064 12.0 0.0 0.25 10.1 0.0 1.9 2 0 0 2 2 2 0 AFG1-like ATPase Rad17 PF03215.10 OAJ26387.1 - 0.064 11.9 0.0 0.087 11.4 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein IstB_IS21 PF01695.12 OAJ26387.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ArgK PF03308.11 OAJ26387.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.4 1 1 0 1 1 1 0 ArgK protein AAA_21 PF13304.1 OAJ26387.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 OAJ26387.1 - 0.11 11.0 0.0 0.22 10.1 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.1 OAJ26387.1 - 0.11 12.0 0.0 0.35 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 OAJ26387.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain NB-ARC PF00931.17 OAJ26387.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DAP3 PF10236.4 OAJ26387.1 - 0.15 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SNF2_N PF00176.18 OAJ26388.1 - 2.5e-34 118.4 0.0 1.1e-33 116.3 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ26388.1 - 0.00035 20.3 0.0 0.00086 19.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FUSC_2 PF13515.1 OAJ26389.1 - 3.3e-21 75.5 10.2 3.3e-21 75.5 7.1 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 OAJ26389.1 - 6.9e-17 61.1 1.7 4.2e-11 42.1 0.2 2.2 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.7 OAJ26389.1 - 2e-10 39.7 11.8 2.7e-10 39.3 2.6 2.9 2 1 0 2 2 2 2 Fusaric acid resistance protein family DUF2421 PF10334.4 OAJ26389.1 - 1.1e-08 35.0 0.3 3.4e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) Na_H_Exchanger PF00999.16 OAJ26390.1 - 4.3e-51 173.6 10.8 5.7e-51 173.2 7.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 OAJ26390.1 - 0.024 14.5 1.5 0.11 12.4 0.0 2.5 2 0 0 2 2 2 0 YrhC-like protein DHquinase_I PF01487.10 OAJ26391.1 - 8.1e-41 140.1 0.0 2.2e-40 138.6 0.0 1.8 1 1 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 OAJ26391.1 - 4.3e-21 75.4 0.0 7.2e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 OAJ26391.1 - 0.002 18.9 0.0 0.0042 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ26391.1 - 0.27 11.5 0.0 0.56 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.1 OAJ26392.1 - 2.4e-64 213.2 88.9 1.8e-10 40.6 0.3 14.3 5 3 13 18 18 18 16 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ26392.1 - 4.3e-58 191.7 103.3 9.8e-06 25.3 0.3 21.7 23 0 0 23 23 23 16 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ26392.1 - 2.2e-14 52.1 53.4 1.1 9.3 0.1 19.4 22 0 0 22 22 21 5 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ26392.1 - 1.4e-08 33.9 16.8 3.9 7.2 0.0 14.1 17 0 0 17 17 17 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ26392.1 - 6e-07 29.0 57.2 0.046 13.3 0.1 12.0 8 4 7 15 15 15 8 TPR repeat DUF3856 PF12968.2 OAJ26392.1 - 3.7e-06 26.8 41.8 0.13 12.0 0.0 8.9 4 3 3 9 9 9 6 Domain of Unknown Function (DUF3856) Cas_Csm6 PF09659.5 OAJ26392.1 - 3.7e-05 22.5 0.4 13 4.2 0.0 6.0 6 1 2 8 8 8 0 CRISPR-associated protein (Cas_Csm6) TPR_8 PF13181.1 OAJ26392.1 - 0.0017 17.9 19.2 24 4.9 0.0 11.3 13 0 0 13 13 13 0 Tetratricopeptide repeat Transcript_VP30 PF11507.3 OAJ26392.1 - 0.0021 17.8 0.0 17 5.2 0.0 4.6 4 0 0 4 4 4 0 Ebola virus-specific transcription factor VP30 MIT PF04212.13 OAJ26392.1 - 0.015 15.1 9.1 0.026 14.4 0.0 5.8 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 OAJ26392.1 - 0.065 13.3 14.2 0.97 9.6 0.9 6.0 5 0 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 OAJ26392.1 - 0.17 11.1 25.9 0.36 10.1 0.1 9.8 12 0 0 12 12 12 0 SHNi-TPR GTPase_Cys_C PF12631.2 OAJ26392.1 - 6.8 7.1 16.9 3.9 7.9 0.2 6.3 7 1 0 8 8 8 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE DUF1183 PF06682.7 OAJ26394.1 - 3.6e-51 174.6 27.3 1e-49 169.9 18.9 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) DUF1768 PF08719.6 OAJ26395.1 - 1.3e-23 83.5 0.0 1.8e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Pkinase PF00069.20 OAJ26396.1 - 1.2e-53 181.8 0.0 1.9e-53 181.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ26396.1 - 3.5e-42 144.2 0.0 4.9e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ26396.1 - 0.014 14.3 0.0 0.033 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 OAJ26396.1 - 0.026 14.2 1.4 0.087 12.5 0.5 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 OAJ26396.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA PF03153.8 OAJ26396.1 - 4.1 7.1 9.5 6.3 6.5 6.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Menin PF05053.8 OAJ26396.1 - 5.9 4.9 7.5 8.4 4.4 5.2 1.3 1 0 0 1 1 1 0 Menin Linker_histone PF00538.14 OAJ26399.1 - 9.5e-18 64.0 0.9 1.2e-17 63.7 0.0 1.6 2 0 0 2 2 2 1 linker histone H1 and H5 family PBP1_TM PF14812.1 OAJ26399.1 - 0.51 10.6 5.0 0.79 10.0 1.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mito_fiss_reg PF05308.6 OAJ26399.1 - 0.62 9.3 12.2 0.087 12.1 2.4 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator SR-25 PF10500.4 OAJ26399.1 - 2 7.8 22.9 2.1 7.7 10.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AFT PF08731.6 OAJ26399.1 - 2.8 8.1 5.7 2 8.6 1.9 2.1 2 0 0 2 2 2 0 Transcription factor AFT CAP_N PF01213.14 OAJ26399.1 - 3.1 7.0 14.9 0.031 13.5 3.4 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Transglut_i_TM PF14400.1 OAJ26399.1 - 5.1 6.5 9.0 0.38 10.2 0.1 2.2 2 0 0 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices Bromodomain PF00439.20 OAJ26400.1 - 1.5e-24 85.6 0.1 3e-24 84.7 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 OAJ26400.1 - 7.5e-09 35.6 0.1 1.7e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAJ26400.1 - 3.8e-08 33.2 0.0 1.6e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family TPR_12 PF13424.1 OAJ26401.1 - 0.0087 15.9 0.6 0.056 13.3 0.0 2.6 4 1 0 4 4 4 1 Tetratricopeptide repeat LRR_6 PF13516.1 OAJ26404.1 - 1.6e-12 46.0 26.9 0.08 13.0 0.0 10.9 10 1 0 10 10 10 5 Leucine Rich repeat LRR_4 PF12799.2 OAJ26404.1 - 3.3e-05 23.4 24.7 0.00072 19.1 0.2 6.8 3 2 6 9 9 9 4 Leucine Rich repeats (2 copies) GAT PF03127.9 OAJ26404.1 - 9e-05 22.3 0.0 0.001 19.0 0.0 2.6 1 1 0 1 1 1 1 GAT domain LRR_1 PF00560.28 OAJ26404.1 - 0.0015 18.2 19.3 15 6.0 0.1 8.8 10 0 0 10 10 10 3 Leucine Rich Repeat LRR_8 PF13855.1 OAJ26404.1 - 0.32 10.7 20.9 0.37 10.5 1.1 5.6 4 2 2 6 6 6 0 Leucine rich repeat KH_3 PF13014.1 OAJ26405.1 - 2.2e-05 23.9 0.3 3.7e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 KH domain KH_1 PF00013.24 OAJ26405.1 - 2.3e-05 23.9 0.3 3.3e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 KH domain DHHA1 PF02272.14 OAJ26405.1 - 0.062 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 DHHA1 domain Cofilin_ADF PF00241.15 OAJ26406.1 - 3.7e-41 139.9 0.2 4.2e-41 139.8 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CBM_4_9 PF02018.12 OAJ26406.1 - 0.063 13.2 0.0 0.087 12.8 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain GFO_IDH_MocA PF01408.17 OAJ26407.1 - 6.2e-17 62.2 0.0 1.2e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 OAJ26407.1 - 2.6e-11 43.2 0.0 6.1e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 OAJ26407.1 - 0.058 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SelP_N PF04592.9 OAJ26408.1 - 8.6 5.6 13.4 12 5.2 0.4 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Mito_carr PF00153.22 OAJ26409.1 - 4.6e-55 183.3 0.3 3.8e-20 71.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CRAL_TRIO_2 PF13716.1 OAJ26410.1 - 5.6e-31 107.4 0.0 1e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 OAJ26410.1 - 2e-23 82.6 0.0 3.5e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Nucleoplasmin PF03066.10 OAJ26410.1 - 0.0029 17.1 1.2 0.0079 15.7 0.8 1.7 1 0 0 1 1 1 1 Nucleoplasmin Paf1 PF03985.8 OAJ26410.1 - 7.7 5.1 9.8 12 4.4 6.8 1.2 1 0 0 1 1 1 0 Paf1 Myc_N PF01056.13 OAJ26410.1 - 8.5 5.4 17.7 0.041 13.0 2.9 2.8 2 0 0 2 2 2 0 Myc amino-terminal region PIN_4 PF13638.1 OAJ26411.1 - 4.5e-05 23.5 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 PIN domain DNA_pol_viral_N PF00242.12 OAJ26411.1 - 0.94 8.4 4.7 1.5 7.8 3.3 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Clat_adaptor_s PF01217.15 OAJ26412.1 - 9.8e-54 180.9 1.3 1.1e-53 180.8 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ICMT PF04140.9 OAJ26413.1 - 3.6e-27 94.4 0.2 6.3e-27 93.6 0.1 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 OAJ26413.1 - 8.1e-13 48.4 1.9 2e-12 47.1 1.3 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 OAJ26413.1 - 0.00011 21.6 0.2 0.00015 21.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 OAJ26413.1 - 0.0043 15.6 0.2 0.0077 14.8 0.2 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family NnrU PF07298.6 OAJ26413.1 - 0.021 14.2 0.5 0.021 14.2 0.3 2.0 2 1 0 2 2 2 0 NnrU protein RRP7 PF12923.2 OAJ26414.1 - 0.068 13.1 0.4 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) FAD_binding_7 PF03441.9 OAJ26415.1 - 1.1e-59 201.9 1.1 1.8e-59 201.2 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 OAJ26415.1 - 6.8e-20 71.4 0.0 1.9e-19 70.0 0.0 1.8 2 0 0 2 2 2 1 DNA photolyase TFIIA PF03153.8 OAJ26415.1 - 1 9.1 5.6 1.7 8.4 3.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EMP70 PF02990.11 OAJ26416.1 - 5.6e-170 566.2 0.0 6.8e-170 565.9 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 NPBW PF15180.1 OAJ26416.1 - 0.044 13.4 0.4 0.14 11.7 0.1 1.9 2 0 0 2 2 2 0 Neuropeptides B and W Helicase_C_2 PF13307.1 OAJ26421.1 - 3.9e-54 183.0 0.0 8e-54 182.0 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 OAJ26421.1 - 8.8e-42 142.4 0.0 1.8e-41 141.4 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 PhoH PF02562.11 OAJ26421.1 - 0.0075 15.5 0.1 1.3 8.1 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Herpes_UL14 PF03580.9 OAJ26421.1 - 0.053 13.3 5.2 0.2 11.4 1.8 2.6 2 0 0 2 2 2 0 Herpesvirus UL14-like protein AAA_22 PF13401.1 OAJ26421.1 - 0.3 11.2 2.9 3.4 7.8 0.0 2.9 2 1 0 2 2 2 0 AAA domain eIF-3_zeta PF05091.7 OAJ26422.1 - 1.6e-159 531.8 0.0 1.8e-86 290.8 0.0 3.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FMN_red PF03358.10 OAJ26423.1 - 6.9e-08 32.1 0.0 9.7e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 OAJ26423.1 - 4.9e-05 23.3 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_4 PF12682.2 OAJ26423.1 - 0.017 14.5 0.0 0.053 12.8 0.0 1.9 2 1 0 2 2 2 0 Flavodoxin Mak10 PF04112.8 OAJ26424.1 - 0.046 12.9 0.1 0.092 11.9 0.1 1.5 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Fun_ATP-synt_8 PF05933.8 OAJ26424.1 - 1.3 9.1 5.5 0.43 10.6 0.6 2.4 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) Abhydro_lipase PF04083.11 OAJ26425.1 - 2.8e-15 55.3 0.0 5.4e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 OAJ26425.1 - 8.7e-06 25.7 0.9 2.2e-05 24.4 0.7 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ26425.1 - 0.00034 20.2 0.1 0.0013 18.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ26425.1 - 0.00073 19.3 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COX4 PF02936.9 OAJ26426.1 - 6.1e-30 103.8 0.0 1.2e-29 102.8 0.0 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase subunit IV DnaJ PF00226.26 OAJ26428.1 - 1.7e-22 78.9 0.1 5.4e-22 77.3 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.1 OAJ26428.1 - 2e-19 68.9 13.7 3e-12 46.0 1.2 5.0 3 2 2 5 5 5 5 TPR repeat TPR_19 PF14559.1 OAJ26428.1 - 3.1e-14 53.0 14.5 1.4e-05 25.3 0.1 5.7 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ26428.1 - 3.1e-14 53.1 26.8 4.6e-07 30.3 0.4 5.8 4 3 2 6 6 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ26428.1 - 1.1e-12 46.9 2.0 0.00071 19.0 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ26428.1 - 1.4e-12 46.4 13.0 0.014 15.2 0.7 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ26428.1 - 1.2e-11 43.8 0.5 0.023 14.8 0.0 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ26428.1 - 3.2e-10 39.6 18.8 0.049 14.2 0.1 6.4 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ26428.1 - 3.3e-09 36.4 10.4 1.9e-05 24.4 0.4 4.8 3 2 1 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 OAJ26428.1 - 3e-06 27.2 4.3 0.04 14.0 0.1 3.8 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 OAJ26428.1 - 0.00018 21.0 1.2 13 5.8 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ26428.1 - 0.021 14.9 11.9 1.7 8.8 0.2 4.8 2 1 2 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.12 OAJ26428.1 - 0.032 14.5 16.8 0.092 13.0 0.9 4.1 3 1 1 4 4 4 0 Bacterial transcriptional activator domain TPR_12 PF13424.1 OAJ26428.1 - 0.074 13.0 13.3 2.8 7.9 0.2 4.3 3 2 1 4 4 3 0 Tetratricopeptide repeat RPT PF13446.1 OAJ26428.1 - 0.074 12.4 0.0 3.1 7.2 0.0 2.6 2 0 0 2 2 2 0 A repeated domain in UCH-protein DUF4603 PF15376.1 OAJ26428.1 - 0.11 9.6 4.4 0.19 8.8 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Cytochrom_B562 PF07361.6 OAJ26428.1 - 0.71 10.3 7.7 1.3 9.4 0.1 3.9 4 0 0 4 4 3 0 Cytochrome b562 Fis1_TPR_C PF14853.1 OAJ26428.1 - 0.84 9.5 5.4 4.5 7.2 0.1 4.2 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 OAJ26428.1 - 1.6 8.6 7.4 11 6.0 0.1 4.3 5 0 0 5 5 2 0 Tetratricopeptide repeat Pex19 PF04614.7 OAJ26428.1 - 3 7.4 7.9 0.69 9.4 2.5 1.9 2 0 0 2 2 2 0 Pex19 protein family TPR_6 PF13174.1 OAJ26428.1 - 4 8.0 17.9 6.6 7.4 0.0 7.1 9 1 0 9 9 7 0 Tetratricopeptide repeat Rad17 PF03215.10 OAJ26429.1 - 2.1e-37 129.0 0.0 3.7e-14 52.2 0.0 4.4 4 1 0 4 4 4 3 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 OAJ26429.1 - 1.4e-06 28.3 0.0 5.7e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ26429.1 - 0.0001 22.4 0.0 0.00037 20.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 OAJ26429.1 - 0.0048 16.0 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 OAJ26429.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 OAJ26429.1 - 0.016 14.3 0.0 0.038 13.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 OAJ26429.1 - 0.021 15.6 0.0 0.099 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 OAJ26429.1 - 0.028 13.9 0.0 0.085 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.16 OAJ26429.1 - 0.046 13.1 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA_28 PF13521.1 OAJ26429.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 OAJ26429.1 - 0.092 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L1 PF00687.16 OAJ26430.1 - 2.7e-46 157.6 0.0 8.5e-46 156.0 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family PGC7_Stella PF15549.1 OAJ26430.1 - 0.046 13.7 0.6 0.046 13.7 0.4 2.4 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain Nucleoplasmin PF03066.10 OAJ26430.1 - 0.27 10.7 9.6 0.46 9.9 6.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin TFIIA PF03153.8 OAJ26430.1 - 0.56 10.0 28.3 0.11 12.3 3.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Phosphodiest PF01663.17 OAJ26431.1 - 5.6e-52 177.2 0.0 1.9e-49 168.9 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 OAJ26431.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily SPT6_acidic PF14632.1 OAJ26431.1 - 0.18 12.0 11.4 0.07 13.3 3.7 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Snf7 PF03357.16 OAJ26432.1 - 9.3e-19 67.4 7.3 1.3e-18 66.9 5.1 1.2 1 0 0 1 1 1 1 Snf7 ACR_tran PF00873.14 OAJ26432.1 - 0.067 10.5 0.2 0.097 10.0 0.1 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family MCPVI PF02993.9 OAJ26432.1 - 2.4 8.2 8.3 0.3 11.1 2.0 2.1 2 0 0 2 2 2 0 Minor capsid protein VI CAP_GLY PF01302.20 OAJ26433.1 - 1.6e-14 53.3 0.4 2.8e-14 52.5 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain zf-CCHC_4 PF14392.1 OAJ26433.1 - 0.25 11.0 6.4 1.5 8.5 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF3087 PF11286.3 OAJ26433.1 - 0.94 8.6 2.4 2 7.6 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DEAD PF00270.24 OAJ26434.1 - 6.6e-32 110.3 0.0 2.1e-31 108.7 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ26434.1 - 2.8e-22 78.3 0.0 7.8e-22 76.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NAD_binding_3 PF03447.11 OAJ26434.1 - 0.017 15.5 0.6 28 5.1 0.0 3.8 3 0 0 3 3 3 0 Homoserine dehydrogenase, NAD binding domain DUF1253 PF06862.7 OAJ26434.1 - 0.078 11.3 0.0 5.5 5.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) ORC4_C PF14629.1 OAJ26435.1 - 1.2e-24 86.8 0.0 3.4e-24 85.3 0.0 1.8 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 OAJ26435.1 - 1.8e-11 44.4 1.4 1.5e-10 41.3 0.5 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 OAJ26435.1 - 0.0062 15.4 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) CDC45 PF02724.9 OAJ26435.1 - 0.69 7.8 14.6 0.11 10.4 4.5 2.1 2 0 0 2 2 2 0 CDC45-like protein AAA_18 PF13238.1 OAJ26435.1 - 1.3 9.3 5.1 1 9.6 0.8 2.8 2 1 0 2 2 2 0 AAA domain HOOK PF05622.7 OAJ26436.1 - 1.3e-48 165.4 41.7 1.3e-48 165.4 28.9 3.5 2 1 1 3 3 3 1 HOOK protein Filament PF00038.16 OAJ26436.1 - 0.01 15.3 86.8 0.066 12.6 10.3 5.0 1 1 1 3 3 3 0 Intermediate filament protein Reo_sigmaC PF04582.7 OAJ26436.1 - 0.039 13.1 23.3 0.058 12.5 3.8 3.8 3 1 2 5 5 5 0 Reovirus sigma C capsid protein Lactamase_B_2 PF12706.2 OAJ26438.1 - 6e-09 35.7 0.3 1.8e-08 34.1 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain PLDc PF00614.17 OAJ26440.1 - 3e-16 58.6 0.3 3.4e-07 29.8 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 OAJ26440.1 - 4.8e-11 42.4 0.0 1e-06 28.5 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 OAJ26440.1 - 9.6e-09 35.0 0.0 2.7e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 PX domain PH PF00169.24 OAJ26440.1 - 0.0052 16.9 0.0 0.023 14.8 0.0 2.0 1 1 0 1 1 1 1 PH domain Thioredoxin PF00085.15 OAJ26441.1 - 0.00011 21.7 0.1 0.00018 21.1 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.11 OAJ26441.1 - 0.06 12.8 0.2 0.092 12.2 0.1 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 DUF3417 PF11897.3 OAJ26441.1 - 0.066 13.1 0.5 0.12 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) Ank_2 PF12796.2 OAJ26444.1 - 9.4e-12 45.1 0.1 6.1e-11 42.5 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ26444.1 - 4.5e-10 38.8 1.3 0.008 15.9 0.1 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 OAJ26444.1 - 7.5e-08 32.6 0.1 0.00027 21.3 0.0 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ26444.1 - 1.7e-06 28.1 0.1 0.021 15.0 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ26444.1 - 2.2e-06 27.3 0.0 0.23 11.7 0.0 4.7 4 1 0 4 4 4 2 Ankyrin repeat Ctr PF04145.10 OAJ26445.1 - 6 6.9 4.4 36 4.3 3.1 2.4 1 0 0 1 1 1 0 Ctr copper transporter family Ribosomal_L7Ae PF01248.21 OAJ26446.1 - 3.6e-26 90.5 0.1 4.3e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 OAJ26446.1 - 0.0033 17.2 0.0 0.0037 17.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 OAJ26446.1 - 0.019 14.7 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Herpes_U34 PF04541.8 OAJ26446.1 - 0.058 12.2 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus virion protein U34 Paf67 PF10255.4 OAJ26447.1 - 1.6e-157 524.5 0.0 2.4e-157 524.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 OAJ26447.1 - 0.0045 16.8 0.0 0.0045 16.8 0.0 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ26447.1 - 0.0069 15.9 0.0 0.054 13.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat SNF2_N PF00176.18 OAJ26448.1 - 1e-70 237.9 0.0 1.9e-70 237.0 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ26448.1 - 2e-12 46.7 0.0 5.2e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ26448.1 - 1.9e-10 40.4 0.0 3.7e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 OAJ26448.1 - 1.6e-07 30.8 3.6 1.6e-07 30.8 2.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ26448.1 - 2.4e-07 30.6 5.1 2.4e-07 30.6 3.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAJ26448.1 - 4.2e-06 26.5 5.6 4.2e-06 26.5 3.9 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 OAJ26448.1 - 1.4e-05 24.8 6.5 1.4e-05 24.8 4.5 2.4 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAJ26448.1 - 2e-05 24.1 5.1 2e-05 24.1 3.6 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ26448.1 - 0.00013 21.6 5.8 0.00013 21.6 4.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ26448.1 - 0.00013 21.5 1.0 0.00037 20.1 0.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 OAJ26448.1 - 0.0012 18.5 3.6 0.0029 17.3 2.5 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-CHY PF05495.7 OAJ26448.1 - 1.4 9.1 11.2 0.052 13.7 1.5 2.5 2 0 0 2 2 2 0 CHY zinc finger Zn_Tnp_IS91 PF14319.1 OAJ26448.1 - 1.7 8.2 12.1 4.1 6.9 0.6 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain BCAS2 PF05700.6 OAJ26449.1 - 1.8e-33 115.8 0.8 2.1e-33 115.6 0.5 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) CASP_C PF08172.7 OAJ26449.1 - 0.00081 18.4 0.0 0.0015 17.5 0.0 1.5 1 0 0 1 1 1 1 CASP C terminal T2SE_Nter PF05157.10 OAJ26449.1 - 0.007 16.4 0.2 0.11 12.5 0.1 2.5 1 1 2 3 3 3 1 Type II secretion system (T2SS), protein E, N-terminal domain Band_7 PF01145.20 OAJ26454.1 - 4.2e-11 43.0 0.0 4.2e-11 43.0 0.0 1.4 2 0 0 2 2 2 1 SPFH domain / Band 7 family DUF4017 PF13209.1 OAJ26455.1 - 0.35 10.6 3.5 0.73 9.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) TcpE PF12648.2 OAJ26455.1 - 1.5 8.9 3.8 5.3 7.2 0.1 2.9 2 1 1 3 3 3 0 TcpE family DUF3087 PF11286.3 OAJ26455.1 - 3.2 6.9 5.6 0.31 10.2 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Carn_acyltransf PF00755.15 OAJ26457.1 - 5.4e-167 556.4 0.0 6.3e-167 556.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AAA_25 PF13481.1 OAJ26458.1 - 0.0023 17.3 0.5 0.16 11.3 0.0 3.3 4 0 0 4 4 4 1 AAA domain DnaB_C PF03796.10 OAJ26458.1 - 0.06 12.2 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain DnaJ-X PF14308.1 OAJ26460.1 - 3.1e-60 202.9 4.8 1.1e-58 197.8 0.2 2.3 2 0 0 2 2 2 2 X-domain of DnaJ-containing DnaJ PF00226.26 OAJ26460.1 - 1.8e-18 66.0 0.2 1.8e-18 66.0 0.2 2.7 4 0 0 4 4 4 1 DnaJ domain FAM70 PF14967.1 OAJ26460.1 - 1.3 8.1 3.2 2 7.5 2.2 1.1 1 0 0 1 1 1 0 FAM70 protein Flp_Fap PF04964.9 OAJ26461.1 - 0.012 15.1 1.9 0.02 14.4 0.5 1.8 1 1 1 2 2 2 0 Flp/Fap pilin component BRI3BP PF14965.1 OAJ26461.1 - 0.057 12.7 0.5 0.064 12.6 0.3 1.1 1 0 0 1 1 1 0 Negative regulator of p53/TP53 DUF759 PF05537.6 OAJ26461.1 - 0.12 11.0 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) DUF3481 PF11980.3 OAJ26461.1 - 0.22 11.3 1.0 0.24 11.2 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) Glycoprotein_B PF00606.13 OAJ26461.1 - 0.62 8.0 2.0 0.65 7.9 1.4 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B SseC PF04888.7 OAJ26461.1 - 1.4 8.1 8.4 2.7 7.2 5.8 1.5 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family CAP PF00188.21 OAJ26462.1 - 9.5e-24 84.2 3.4 1.9e-23 83.2 2.4 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family zf-Tim10_DDP PF02953.10 OAJ26462.1 - 2.2e-16 58.8 0.8 4e-16 58.0 0.5 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger BUD22 PF09073.5 OAJ26463.1 - 2.7e-44 151.9 41.3 1.9e-43 149.1 28.6 2.3 1 1 0 1 1 1 1 BUD22 Ten1_2 PF15490.1 OAJ26464.1 - 4.1e-06 26.3 0.0 2.3e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit cobW PF02492.14 OAJ26465.1 - 1.4e-33 115.8 0.0 1.9e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 OAJ26465.1 - 7e-06 25.0 1.7 2.1e-05 23.4 1.2 1.6 1 1 0 1 1 1 1 ArgK protein GTP_EFTU PF00009.22 OAJ26465.1 - 0.0066 15.9 0.0 1.1 8.6 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 OAJ26465.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 OAJ26465.1 - 0.015 15.5 0.1 0.035 14.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 OAJ26465.1 - 0.019 15.8 0.0 0.036 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAJ26465.1 - 0.049 13.3 0.1 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 OAJ26465.1 - 0.077 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.22 OAJ26465.1 - 0.094 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 OAJ26465.1 - 0.11 12.4 0.0 0.59 10.1 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase T2SE PF00437.15 OAJ26465.1 - 0.13 11.1 0.0 0.28 10.0 0.0 1.4 1 1 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 OAJ26465.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.9 OAJ26465.1 - 0.17 10.8 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain SelP_N PF04592.9 OAJ26465.1 - 0.36 10.1 10.2 0.52 9.6 7.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 OAJ26465.1 - 3.3 6.6 6.6 4.5 6.1 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ufd2P_core PF10408.4 OAJ26466.1 - 2.3e-177 591.0 0.0 2.8e-177 590.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 OAJ26466.1 - 4.1e-26 90.7 0.4 1.3e-25 89.1 0.3 2.0 1 0 0 1 1 1 1 U-box domain Sec5 PF15469.1 OAJ26468.1 - 2.9e-55 186.8 1.6 3.9e-54 183.1 0.0 3.0 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.6 OAJ26468.1 - 0.0098 15.7 0.0 0.062 13.1 0.0 2.5 1 0 0 1 1 1 1 Vps51/Vps67 RRM_6 PF14259.1 OAJ26469.1 - 2.4e-10 40.2 0.0 4.5e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ26469.1 - 7.3e-10 38.3 0.0 8e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ26469.1 - 1.9e-05 24.4 0.0 3.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4283 PF14111.1 OAJ26469.1 - 0.067 12.2 0.0 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4283) RNA_Me_trans PF04252.8 OAJ26470.1 - 9.4e-18 64.3 0.0 8e-15 54.7 0.0 3.0 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase HutP PF09021.6 OAJ26471.1 - 0.33 11.1 4.4 2 8.6 0.2 2.5 2 1 0 2 2 2 0 HutP UPF0203 PF05254.7 OAJ26472.1 - 1.9e-12 46.8 0.0 2.3e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0203) Serglycin PF04360.7 OAJ26472.1 - 0.36 10.5 6.7 0.39 10.4 0.0 2.2 2 0 0 2 2 2 0 Serglycin Pol_alpha_B_N PF08418.5 OAJ26472.1 - 5.8 6.3 7.3 7.1 6.0 5.0 1.3 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal AdoMet_MTase PF07757.8 OAJ26473.1 - 1.1e-30 105.9 0.0 1.4e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 OAJ26473.1 - 0.022 14.4 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pec_lyase_C PF00544.14 OAJ26474.1 - 2.1e-19 69.7 0.8 3.2e-19 69.2 0.6 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 OAJ26474.1 - 0.00011 22.0 5.7 0.00047 19.9 3.9 2.0 1 1 0 1 1 1 1 Right handed beta helix region Kelch_5 PF13854.1 OAJ26475.1 - 7e-35 118.4 11.7 1.7e-08 34.2 0.3 7.0 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 OAJ26475.1 - 2e-32 110.5 24.7 1.2e-08 34.8 0.1 8.1 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 OAJ26475.1 - 3.1e-32 110.1 21.2 5.7e-08 32.4 0.1 8.3 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_1 PF01344.20 OAJ26475.1 - 3.4e-23 80.9 17.0 4e-07 29.4 2.0 6.2 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.1 OAJ26475.1 - 2e-22 78.3 14.9 4.3e-06 26.6 0.0 7.1 5 1 2 7 7 7 5 Kelch motif Kelch_2 PF07646.10 OAJ26475.1 - 1.9e-16 59.1 16.0 0.0017 18.0 0.1 7.1 6 1 0 6 6 6 5 Kelch motif RAG2 PF03089.9 OAJ26475.1 - 0.0037 16.0 0.8 1.5 7.4 0.0 3.7 4 0 0 4 4 4 1 Recombination activating protein 2 Tropomyosin_1 PF12718.2 OAJ26475.1 - 0.014 15.2 0.5 0.014 15.2 0.3 6.3 3 1 3 6 6 6 0 Tropomyosin like AAA_13 PF13166.1 OAJ26475.1 - 5.2 5.3 32.2 0.12 10.7 7.1 3.9 3 1 0 4 4 4 0 AAA domain DAO PF01266.19 OAJ26476.1 - 7e-48 163.3 0.3 1.2e-47 162.5 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase EF-hand_7 PF13499.1 OAJ26476.1 - 2.3e-06 27.6 1.0 5.2e-06 26.4 0.7 1.6 1 0 0 1 1 1 1 EF-hand domain pair FAD_binding_2 PF00890.19 OAJ26476.1 - 8.3e-06 24.9 5.5 9.3e-05 21.4 3.8 2.2 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 OAJ26476.1 - 2.2e-05 23.7 0.5 2.2e-05 23.7 0.4 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAJ26476.1 - 0.00046 20.1 0.2 0.0066 16.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 OAJ26476.1 - 0.00085 18.4 0.3 0.0027 16.8 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 OAJ26476.1 - 0.0073 16.1 0.7 0.044 13.6 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 OAJ26476.1 - 0.0088 15.3 0.4 0.02 14.2 0.3 1.6 1 0 0 1 1 1 1 EF hand GIDA PF01134.17 OAJ26476.1 - 0.017 14.0 0.2 0.15 10.8 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 OAJ26476.1 - 0.02 14.5 0.2 0.059 13.0 0.2 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 OAJ26476.1 - 0.028 14.4 0.2 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ26476.1 - 0.15 12.5 0.7 0.36 11.2 0.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.1 OAJ26476.1 - 0.18 11.4 1.6 1.7 8.2 0.1 3.0 3 1 1 4 4 4 0 EF-hand domain pair NAD_binding_8 PF13450.1 OAJ26476.1 - 2 8.4 6.1 0.26 11.3 0.4 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PNRC PF15365.1 OAJ26477.1 - 2.9 7.9 6.6 9.7 6.2 3.5 2.7 2 1 0 2 2 2 0 Proline-rich nuclear receptor coactivator Vac7 PF12751.2 OAJ26478.1 - 0.00059 18.7 0.3 0.0007 18.5 0.2 1.1 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 Myc_N PF01056.13 OAJ26478.1 - 0.019 14.1 0.9 0.026 13.6 0.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region SAGA-Tad1 PF12767.2 OAJ26478.1 - 0.043 13.4 0.7 0.05 13.2 0.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit TSP9 PF11493.3 OAJ26478.1 - 0.17 12.4 0.6 0.37 11.3 0.1 1.9 1 1 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 MRC1 PF09444.5 OAJ26478.1 - 1 9.6 7.8 1.6 9.0 5.4 1.2 1 0 0 1 1 1 0 MRC1-like domain CPSF_A PF03178.10 OAJ26479.1 - 1.9e-79 267.0 0.0 6.8e-79 265.2 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 OAJ26479.1 - 1.4e-67 227.9 0.0 2e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term IN_DBD_C PF00552.16 OAJ26479.1 - 0.22 11.0 0.0 0.42 10.0 0.0 1.4 1 0 0 1 1 1 0 Integrase DNA binding domain Proteasome PF00227.21 OAJ26480.1 - 5.1e-24 84.6 0.2 5.7e-24 84.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit zf-B_box PF00643.19 OAJ26481.1 - 0.25 11.2 3.2 0.34 10.8 2.2 1.2 1 0 0 1 1 1 0 B-box zinc finger 4HBT_2 PF13279.1 OAJ26482.1 - 3.2e-07 30.8 0.0 3.9e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 OAJ26482.1 - 3e-06 27.2 0.0 4.9e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 OAJ26482.1 - 0.022 13.6 0.3 0.041 12.8 0.2 1.4 2 0 0 2 2 2 0 Acyl-ACP thioesterase PBP_sp32 PF07222.7 OAJ26483.1 - 0.15 11.2 1.3 0.17 11.0 0.9 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 ADH_N PF08240.7 OAJ26484.1 - 2.4e-26 91.6 1.5 3.8e-26 90.9 1.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ26484.1 - 1.6e-08 34.1 0.1 0.0024 17.3 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 OAJ26484.1 - 0.002 17.7 0.9 0.0061 16.1 0.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.14 OAJ26484.1 - 0.06 12.5 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3136 PF11334.3 OAJ26484.1 - 0.067 12.6 0.0 0.28 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) Pyr_redox_3 PF13738.1 OAJ26484.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PCI PF01399.22 OAJ26485.1 - 5.5e-15 55.5 0.0 3e-14 53.1 0.0 2.2 2 1 0 2 2 2 1 PCI domain Rubredoxin PF00301.15 OAJ26486.1 - 0.085 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Rubredoxin Raftlin PF15250.1 OAJ26486.1 - 4.4 5.7 10.0 3.4 6.1 0.1 2.1 2 0 0 2 2 2 0 Raftlin SNARE PF05739.14 OAJ26487.1 - 2.2e-16 59.2 2.3 3.2e-16 58.7 0.7 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 OAJ26487.1 - 5.3e-14 52.2 4.3 1.8e-13 50.4 0.0 2.7 2 1 1 3 3 3 1 Syntaxin Sed5p PF11416.3 OAJ26487.1 - 0.0044 16.4 0.1 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 Integral membrane protein Sed5p FlaC_arch PF05377.6 OAJ26487.1 - 0.0063 16.3 0.7 0.019 14.8 0.2 2.1 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.6 OAJ26487.1 - 0.041 14.2 1.2 2.2 8.7 0.0 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal SlyX PF04102.7 OAJ26487.1 - 0.058 13.7 0.9 0.32 11.3 0.3 2.5 2 1 0 2 2 2 0 SlyX Peripla_BP_2 PF01497.13 OAJ26487.1 - 0.085 11.9 0.9 0.2 10.7 0.4 1.7 1 1 1 2 2 2 0 Periplasmic binding protein DUF1664 PF07889.7 OAJ26487.1 - 0.17 11.6 1.0 0.75 9.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 OAJ26487.1 - 0.22 11.3 7.0 1.9 8.3 0.2 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF148 PF02520.12 OAJ26487.1 - 0.35 10.6 3.3 0.9 9.3 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF148 NPV_P10 PF05531.7 OAJ26487.1 - 5 7.4 6.3 67 3.8 0.2 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Topoisom_I_N PF02919.10 OAJ26488.1 - 1.1e-79 266.7 1.4 1.1e-79 266.7 1.0 3.5 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 OAJ26488.1 - 9.1e-58 195.1 0.2 9.1e-58 195.1 0.1 2.5 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 OAJ26488.1 - 2.3e-17 62.4 0.1 2.2e-14 52.8 0.0 3.1 2 0 0 2 2 2 2 C-terminal topoisomerase domain EPSP_synthase PF00275.15 OAJ26489.1 - 1e-45 155.9 0.0 1.3e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) HTH_3 PF01381.17 OAJ26489.1 - 0.0011 18.7 0.0 0.082 12.7 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix HSP20 PF00011.16 OAJ26490.1 - 2.3e-17 62.7 0.9 4.3e-12 45.7 0.1 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family PEX11 PF05648.9 OAJ26491.1 - 9.2e-14 51.2 0.0 1.6e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Pkinase PF00069.20 OAJ26493.1 - 1.9e-72 243.5 0.0 3.1e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ26493.1 - 7.3e-35 120.2 0.0 1.2e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ26493.1 - 0.002 17.1 0.0 0.0031 16.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SNARE PF05739.14 OAJ26494.1 - 3.3e-05 23.4 0.0 4.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 OAJ26494.1 - 0.03 13.7 0.2 0.039 13.3 0.1 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 L51_S25_CI-B8 PF05047.11 OAJ26495.1 - 8.5e-10 38.2 0.2 1.3e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Rad51 PF08423.6 OAJ26496.1 - 4.2e-09 35.7 0.0 1.1e-08 34.2 0.0 1.6 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 OAJ26496.1 - 1.5e-07 30.9 0.2 4.5e-07 29.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 OAJ26496.1 - 1.4e-05 24.3 0.1 2.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 OAJ26496.1 - 0.00012 21.2 0.1 0.00026 20.1 0.1 1.5 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.1 OAJ26496.1 - 0.006 16.3 0.2 0.03 14.0 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain PAXNEB PF05625.6 OAJ26496.1 - 0.17 10.6 0.4 0.33 9.7 0.1 1.5 2 0 0 2 2 2 0 PAXNEB protein HSP20 PF00011.16 OAJ26497.1 - 2.3e-17 62.7 0.9 4.3e-12 45.7 0.1 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Inhibitor_I9 PF05922.11 OAJ26506.1 - 3.6e-10 40.2 0.1 1.3e-09 38.5 0.1 1.7 1 1 0 1 1 1 1 Peptidase inhibitor I9 Brix PF04427.13 OAJ26507.1 - 1e-36 126.3 0.0 1.6e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Brix domain Spt5_N PF11942.3 OAJ26507.1 - 0.068 13.7 26.1 0.24 12.0 0.7 3.2 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DUF2890 PF11081.3 OAJ26507.1 - 0.085 12.9 9.9 0.35 10.9 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 OAJ26507.1 - 0.31 8.9 19.2 0.13 10.1 5.1 2.1 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.9 OAJ26507.1 - 1.9 6.4 21.5 0.9 7.4 7.6 2.1 2 0 0 2 2 2 0 CDC45-like protein Sporozoite_P67 PF05642.6 OAJ26507.1 - 2.9 5.6 10.8 0.42 8.4 1.9 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen BNIP2 PF12496.3 OAJ26507.1 - 4.4 7.4 10.4 4.3 7.5 1.5 2.4 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CPSase_L_D2 PF02786.12 OAJ26508.1 - 8.7e-73 244.0 0.0 8.7e-72 240.8 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 OAJ26508.1 - 1.5e-43 147.3 0.0 4.1e-43 145.9 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 OAJ26508.1 - 1.9e-35 121.0 0.0 4.1e-35 120.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 OAJ26508.1 - 5.3e-15 55.6 0.0 1.2e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 OAJ26508.1 - 6.9e-14 51.2 2.2 1.4e-13 50.2 1.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 OAJ26508.1 - 5.8e-12 44.9 0.0 7.8e-11 41.2 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 OAJ26508.1 - 1.2e-09 37.9 0.0 2.4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 OAJ26508.1 - 4.1e-06 26.3 0.4 1.2e-05 24.8 0.2 1.8 1 1 0 1 1 1 1 Biotin-lipoyl like ATP-grasp PF02222.17 OAJ26508.1 - 4.7e-06 26.0 0.0 9.9e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 OAJ26508.1 - 0.0017 18.6 2.5 0.86 9.9 0.0 2.9 3 0 0 3 3 2 2 HlyD family secretion protein DUF3322 PF11795.3 OAJ26508.1 - 0.007 16.0 0.5 0.014 14.9 0.3 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) GARS_A PF01071.14 OAJ26508.1 - 0.0077 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 OAJ26508.1 - 0.046 13.1 0.0 0.34 10.3 0.0 2.1 1 1 0 1 1 1 0 RimK-like ATP-grasp domain P53_tetramer PF07710.6 OAJ26508.1 - 0.1 11.7 0.1 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 P53 tetramerisation motif Acyl-CoA_dh_1 PF00441.19 OAJ26509.1 - 1e-42 145.8 1.0 1.7e-42 145.0 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAJ26509.1 - 1.8e-33 115.5 0.0 3.1e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ26509.1 - 4.1e-19 67.8 0.1 9.9e-19 66.6 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 OAJ26509.1 - 1.5e-16 60.8 0.5 2.4e-16 60.1 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Mre11_DNA_bind PF04152.9 OAJ26510.1 - 1.2e-43 148.9 5.1 1.2e-43 148.9 3.5 1.8 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 OAJ26510.1 - 6.5e-22 77.9 0.5 9.6e-22 77.3 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DHFR_1 PF00186.14 OAJ26511.1 - 7.6e-27 93.8 0.0 2.7e-23 82.3 0.0 2.5 2 1 0 2 2 2 2 Dihydrofolate reductase SSF PF00474.12 OAJ26512.1 - 8.8e-21 74.0 20.1 1.5e-20 73.2 13.9 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family S-AdoMet_synt_C PF02773.11 OAJ26513.1 - 3.9e-75 250.1 0.2 7.4e-75 249.2 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 OAJ26513.1 - 1.8e-48 163.3 0.0 3.2e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 OAJ26513.1 - 6.8e-44 148.1 0.1 1.3e-43 147.2 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain GST_N_3 PF13417.1 OAJ26514.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ26514.1 - 6.5e-11 42.0 0.0 1.1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAJ26514.1 - 1.8e-08 34.1 0.0 2.9e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAJ26514.1 - 6e-07 29.3 0.0 9.6e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 OAJ26514.1 - 8.2e-06 25.9 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 OAJ26514.1 - 1.7e-05 25.2 0.0 3.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 OAJ26514.1 - 0.0073 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin RNA_pol_I_A49 PF06870.7 OAJ26514.1 - 0.073 11.6 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor Dfp1_Him1_M PF08630.5 OAJ26515.1 - 4.4e-30 104.0 0.0 7.6e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 OAJ26515.1 - 1.3e-21 75.9 1.0 2.8e-21 74.9 0.7 1.6 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 OAJ26515.1 - 0.0017 18.4 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 OAJ26515.1 - 0.008 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain MBOAT_2 PF13813.1 OAJ26516.1 - 9.8e-14 51.2 0.3 4.5e-06 26.6 0.0 3.1 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family Polysacc_deac_1 PF01522.16 OAJ26517.1 - 1.5e-14 53.6 0.0 3.4e-14 52.5 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase Ribophorin_I PF04597.9 OAJ26518.1 - 3.1e-102 342.3 0.0 6e-71 239.2 0.0 2.0 2 0 0 2 2 2 2 Ribophorin I DUF11 PF01345.13 OAJ26518.1 - 0.077 13.0 0.3 0.24 11.4 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF11 WD40 PF00400.27 OAJ26519.1 - 3.3e-18 64.7 8.2 0.0029 17.4 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat SRA1 PF07304.6 OAJ26519.1 - 0.0016 18.1 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Pyr_redox_3 PF13738.1 OAJ26520.1 - 3e-19 69.9 0.0 1.1e-17 64.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAJ26520.1 - 1.8e-09 36.3 0.0 2.3e-05 22.8 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAJ26520.1 - 1e-08 35.0 0.1 4.3e-08 33.0 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAJ26520.1 - 2.3e-08 33.9 0.7 0.00035 20.3 0.2 3.5 3 1 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 OAJ26520.1 - 2.5e-06 26.6 0.0 0.0001 21.3 0.0 2.9 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 OAJ26520.1 - 4.9e-05 22.3 0.0 0.0034 16.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 OAJ26520.1 - 0.044 12.6 0.2 0.24 10.2 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 OAJ26520.1 - 0.12 11.2 0.0 9 5.0 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 OAJ26520.1 - 0.18 10.8 0.2 0.5 9.4 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.1 OAJ26521.1 - 4.5e-25 88.9 0.0 2.2e-24 86.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAJ26521.1 - 6.7e-11 41.0 0.0 1.1e-09 37.0 0.0 2.3 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAJ26521.1 - 1.2e-09 38.0 0.0 2.2e-08 33.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAJ26521.1 - 1.6e-09 37.9 0.0 1.3e-07 31.6 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ26521.1 - 2e-07 30.2 0.0 0.00064 18.7 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 OAJ26521.1 - 6.7e-06 25.2 0.1 0.0028 16.6 0.1 3.6 3 1 0 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAJ26521.1 - 1.9e-05 23.8 0.1 0.00019 20.6 0.0 2.3 3 0 0 3 3 3 1 Thi4 family NAD_binding_9 PF13454.1 OAJ26521.1 - 7.6e-05 22.5 0.9 0.48 10.1 0.0 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 OAJ26521.1 - 0.00033 19.6 0.1 0.0016 17.3 0.0 2.1 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.7 OAJ26521.1 - 0.00047 19.1 0.1 0.081 11.8 0.0 2.6 2 0 0 2 2 2 1 Lycopene cyclase protein Shikimate_DH PF01488.15 OAJ26521.1 - 0.0018 18.4 0.0 1.8 8.6 0.0 2.7 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Mqo PF06039.10 OAJ26521.1 - 0.0036 15.5 0.2 0.62 8.1 0.0 2.6 2 1 1 3 3 3 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.22 OAJ26521.1 - 0.011 16.1 0.0 7.2 7.0 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAJ26521.1 - 0.023 13.5 0.2 1.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 OAJ26521.1 - 0.14 11.1 0.3 0.4 9.6 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 OAJ26521.1 - 0.17 10.2 0.3 0.67 8.3 0.0 2.1 3 0 0 3 3 3 0 HI0933-like protein TENA_THI-4 PF03070.11 OAJ26522.1 - 1.4e-15 57.6 0.0 1.1e-08 35.1 0.0 2.1 2 0 0 2 2 2 2 TENA/THI-4/PQQC family WLM PF08325.5 OAJ26523.1 - 0.07 13.0 2.3 0.1 12.4 1.6 1.2 1 0 0 1 1 1 0 WLM domain DUF1183 PF06682.7 OAJ26523.1 - 0.093 12.3 5.3 0.11 12.1 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Pap_E4 PF02711.9 OAJ26523.1 - 0.12 13.2 2.2 0.14 12.9 1.5 1.2 1 0 0 1 1 1 0 E4 protein DUF2360 PF10152.4 OAJ26523.1 - 0.21 11.8 4.8 0.22 11.8 3.3 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) CAP_N PF01213.14 OAJ26523.1 - 0.32 10.2 1.4 0.36 10.0 1.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2201_N PF13203.1 OAJ26523.1 - 0.78 8.8 8.4 1 8.5 5.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain VirionAssem_T7 PF11653.3 OAJ26523.1 - 0.79 10.5 4.5 1.3 9.8 3.1 1.3 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein zf-C3HC4_2 PF13923.1 OAJ26524.1 - 1.8e-08 34.2 3.0 1.8e-08 34.2 2.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ26524.1 - 5.4e-08 32.5 1.7 6.5e-07 29.0 0.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 OAJ26524.1 - 1.3e-07 31.1 1.2 1.3e-07 31.1 0.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ26524.1 - 2.3e-05 23.9 3.2 0.00024 20.7 0.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ26524.1 - 0.0002 21.0 1.8 0.0002 21.0 1.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 OAJ26524.1 - 0.00086 19.1 3.9 0.00086 19.1 2.7 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 OAJ26524.1 - 0.0034 17.0 0.9 0.0034 17.0 0.7 1.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-dskA_traR PF01258.12 OAJ26524.1 - 0.049 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger zf-Nse PF11789.3 OAJ26524.1 - 0.088 12.3 0.3 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Hid1 PF12722.2 OAJ26524.1 - 4.9 4.7 3.6 7.4 4.1 2.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Complex1_LYR PF05347.10 OAJ26525.1 - 4.4e-05 23.2 1.0 0.00013 21.6 0.4 2.1 2 1 0 2 2 2 1 Complex 1 protein (LYR family) Methyltransf_23 PF13489.1 OAJ26525.1 - 0.00023 20.9 0.0 0.0014 18.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Complex1_LYR_1 PF13232.1 OAJ26525.1 - 0.0084 16.2 0.4 0.0084 16.2 0.3 2.0 2 1 0 2 2 2 1 Complex1_LYR-like Rhodanese PF00581.15 OAJ26525.1 - 0.031 14.6 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain TehB PF03848.9 OAJ26525.1 - 0.2 10.8 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Spc7 PF08317.6 OAJ26526.1 - 1.4e-08 33.7 5.1 2.2e-08 33.1 3.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein IncA PF04156.9 OAJ26526.1 - 0.077 12.5 8.5 0.15 11.6 5.9 1.5 1 0 0 1 1 1 0 IncA protein Snf7 PF03357.16 OAJ26527.1 - 2.9e-31 108.1 13.8 3.9e-31 107.7 9.6 1.2 1 0 0 1 1 1 1 Snf7 TIP39 PF14980.1 OAJ26527.1 - 0.16 11.6 1.7 0.4 10.3 1.2 1.7 1 0 0 1 1 1 0 TIP39 peptide C1q PF00386.16 OAJ26527.1 - 0.16 11.9 0.4 0.29 11.1 0.2 1.4 1 0 0 1 1 1 0 C1q domain RbsD_FucU PF05025.8 OAJ26527.1 - 1.7 8.9 5.0 0.53 10.6 1.3 1.7 2 0 0 2 2 2 0 RbsD / FucU transport protein family RRM_1 PF00076.17 OAJ26528.1 - 9.1e-17 60.4 0.0 1.8e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ26528.1 - 4.9e-13 48.8 0.0 8e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ26528.1 - 1.6e-09 37.4 0.0 2.8e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-T PF15511.1 OAJ26528.1 - 0.0031 16.8 9.4 0.0031 16.8 6.5 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T DUF3449 PF11931.3 OAJ26528.1 - 0.018 14.5 1.9 0.02 14.3 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Limkain-b1 PF11608.3 OAJ26528.1 - 0.054 13.2 0.1 15 5.3 0.0 2.7 2 1 0 2 2 2 0 Limkain b1 RRN3 PF05327.6 OAJ26528.1 - 0.67 7.9 3.2 0.89 7.5 2.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Dicty_REP PF05086.7 OAJ26528.1 - 0.81 7.3 5.8 1.1 6.9 4.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nucleoplasmin PF03066.10 OAJ26528.1 - 0.81 9.1 9.7 1.9 7.9 6.7 1.6 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 OAJ26528.1 - 1.9 7.7 8.1 2.9 7.0 5.6 1.3 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 OAJ26528.1 - 2.5 6.0 10.2 0.033 12.2 1.6 1.7 2 0 0 2 2 2 0 CDC45-like protein MSP1_C PF07462.6 OAJ26528.1 - 3.8 5.7 15.4 6.7 4.9 10.7 1.4 1 1 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DNA_pol_phi PF04931.8 OAJ26528.1 - 4.4 4.9 17.7 7 4.2 12.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.6 OAJ26528.1 - 5 4.8 9.0 7.2 4.3 6.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleo_P87 PF07267.6 OAJ26528.1 - 9.2 4.8 11.4 0.28 9.8 2.9 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 CBM_20 PF00686.14 OAJ26529.1 - 0.018 14.6 0.1 0.059 12.9 0.1 1.9 1 0 0 1 1 1 0 Starch binding domain COX15-CtaA PF02628.10 OAJ26529.1 - 0.67 8.7 3.7 15 4.3 0.0 2.5 2 1 0 2 2 2 0 Cytochrome oxidase assembly protein Glt_symporter PF03616.9 OAJ26529.1 - 3.9 5.8 5.5 5.5 5.3 0.0 3.0 3 0 0 3 3 3 0 Sodium/glutamate symporter DUF1639 PF07797.9 OAJ26530.1 - 0.13 11.6 0.8 0.38 10.1 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) Peroxin-13_N PF04088.8 OAJ26531.1 - 4.2e-46 156.7 0.0 6.5e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 OAJ26531.1 - 3e-12 45.8 0.0 5.5e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ26531.1 - 3.3e-12 45.6 0.0 6.3e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ26531.1 - 2e-11 43.3 0.0 3.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain ATP-synt_C PF00137.16 OAJ26532.1 - 9e-28 95.9 31.7 4.6e-16 58.4 7.3 3.0 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.19 OAJ26532.1 - 4.3 6.9 11.0 0.18 11.4 1.1 3.0 1 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ras PF00071.17 OAJ26533.1 - 1.6e-45 154.4 0.0 1.9e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ26533.1 - 3.3e-13 50.1 0.0 4.3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ26533.1 - 3.2e-07 29.7 0.0 4.1e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ26533.1 - 0.00019 20.9 0.0 0.00065 19.1 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 OAJ26533.1 - 0.00044 19.4 0.0 0.00047 19.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Glutaredoxin PF00462.19 OAJ26533.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin ATP_bind_1 PF03029.12 OAJ26533.1 - 0.037 13.5 0.1 0.57 9.6 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 OAJ26533.1 - 0.04 13.8 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 OAJ26533.1 - 0.045 13.6 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 OAJ26533.1 - 0.056 12.7 0.0 0.15 11.3 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B NUDIX_2 PF13869.1 OAJ26534.1 - 2.1e-80 268.4 0.0 2.4e-80 268.2 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Mito_carr PF00153.22 OAJ26535.1 - 8.7e-70 230.5 3.6 1.7e-23 82.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PARP PF00644.15 OAJ26537.1 - 6.2e-08 32.3 0.1 9.8e-07 28.4 0.0 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.6 OAJ26538.1 - 1.9e-18 66.7 0.2 2.3e-18 66.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.6 OAJ26538.1 - 0.0028 17.1 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Bacteriophage protein GP30.3 PARP PF00644.15 OAJ26539.1 - 1.9e-15 56.8 0.1 9.4e-10 38.2 0.0 2.9 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain FdhE PF04216.7 OAJ26539.1 - 0.0092 15.7 0.1 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation Fasciclin PF02469.17 OAJ26539.1 - 0.021 14.8 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Fasciclin domain zf-HC5HC2H PF13771.1 OAJ26539.1 - 0.65 10.1 5.5 8.2 6.6 0.2 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain NUP PF06516.6 OAJ26540.1 - 2.2e-113 378.2 0.1 2.7e-113 377.9 0.1 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Aldo_ket_red PF00248.16 OAJ26541.1 - 2.5e-42 144.6 0.0 3e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HxlR PF01638.12 OAJ26541.1 - 0.078 12.6 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 HxlR-like helix-turn-helix GRP PF07172.6 OAJ26542.1 - 2.8 8.4 12.5 1.9 9.0 7.7 1.4 1 1 0 1 1 1 0 Glycine rich protein family CNH PF00780.17 OAJ26544.1 - 8.4e-36 123.7 0.0 1.5e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 OAJ26544.1 - 4.4e-24 85.3 0.2 7.3e-24 84.6 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 OAJ26544.1 - 2.3e-05 24.0 0.0 5.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_5 PF15405.1 OAJ26544.1 - 0.0053 16.7 0.0 0.018 14.9 0.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain Fungal_trans PF04082.13 OAJ26545.1 - 0.0047 15.8 2.1 0.0076 15.1 0.4 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ26545.1 - 0.053 13.4 3.5 0.089 12.7 2.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3099 PF11298.3 OAJ26546.1 - 0.75 9.5 2.3 1.5 8.5 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) UAA PF08449.6 OAJ26547.1 - 5.3e-72 242.3 4.8 4.1e-53 180.2 0.0 2.1 2 0 0 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.10 OAJ26547.1 - 0.0003 19.9 0.1 0.00056 19.0 0.1 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter SRF-TF PF00319.13 OAJ26548.1 - 2.7e-12 45.7 0.1 4.7e-12 44.9 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Serglycin PF04360.7 OAJ26548.1 - 4.7e-05 23.1 9.3 0.002 17.8 0.0 3.2 3 0 0 3 3 3 2 Serglycin MIP PF00230.15 OAJ26554.1 - 6.2e-22 78.1 9.5 2.7e-11 43.3 0.8 2.1 1 1 1 2 2 2 2 Major intrinsic protein Cucumo_2B PF03263.8 OAJ26554.1 - 0.0054 16.9 5.0 0.01 16.1 3.4 1.4 1 0 0 1 1 1 1 Cucumovirus protein 2B CTP_transf_2 PF01467.21 OAJ26555.1 - 1.1e-30 106.7 0.0 1.5e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Pro_isomerase PF00160.16 OAJ26556.1 - 4.7e-29 101.5 0.0 7.4e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 OAJ26556.1 - 1e-13 50.7 0.0 1.7e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ26556.1 - 1e-10 41.3 0.0 2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ26556.1 - 9.8e-07 28.5 0.1 1.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pirin PF02678.11 OAJ26557.1 - 5e-29 100.3 0.0 9.2e-29 99.4 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 OAJ26557.1 - 2e-23 82.4 0.0 4.9e-23 81.1 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 OAJ26557.1 - 0.008 15.6 0.6 0.039 13.4 0.5 2.0 2 0 0 2 2 2 1 Cupin domain Abhydrolase_5 PF12695.2 OAJ26558.1 - 0.00014 21.5 0.0 0.0027 17.4 0.0 2.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ26558.1 - 0.0008 19.3 0.1 0.43 10.4 0.0 2.5 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ26558.1 - 0.028 13.9 0.1 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAJ26558.1 - 0.083 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family EspF PF04806.7 OAJ26559.1 - 0.096 12.8 6.7 0.27 11.4 3.2 2.8 2 0 0 2 2 2 0 EspF protein repeat Plus-3 PF03126.13 OAJ26560.1 - 2e-09 37.4 0.0 3.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain ECSIT PF06239.6 OAJ26560.1 - 0.077 11.8 0.1 0.17 10.7 0.1 1.5 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway CLASP_N PF12348.3 OAJ26561.1 - 1.2e-17 64.1 0.0 9.7e-05 21.8 0.0 5.1 5 0 0 5 5 5 3 CLASP N terminal HEAT_2 PF13646.1 OAJ26561.1 - 9.3e-14 51.4 6.6 0.022 15.0 0.0 8.3 6 3 2 8 8 8 4 HEAT repeats HEAT PF02985.17 OAJ26561.1 - 6.2e-13 47.6 14.6 0.0017 18.2 0.1 9.1 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.1 OAJ26561.1 - 0.00016 22.0 12.0 0.6 10.6 0.0 6.8 6 1 1 7 7 5 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 OAJ26561.1 - 0.00029 21.1 0.0 18 5.7 0.0 5.5 4 2 2 6 6 6 0 Vacuolar 14 Fab1-binding region Proteasom_PSMB PF10508.4 OAJ26561.1 - 0.0024 16.2 0.0 1.6 6.8 0.0 2.9 3 0 0 3 3 3 2 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 OAJ26561.1 - 0.0038 17.0 0.0 0.95 9.2 0.0 4.1 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 OAJ26561.1 - 0.035 13.9 4.8 1.4 8.8 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 OAJ26561.1 - 0.05 13.5 1.5 5.5 6.9 0.0 3.9 4 0 0 4 4 3 0 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 OAJ26561.1 - 0.051 13.5 2.0 6.4 6.8 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Ipi1_N PF12333.3 OAJ26561.1 - 0.18 11.8 0.1 16 5.4 0.0 3.9 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation DUF1900 PF08954.6 OAJ26562.1 - 4.4e-45 152.5 0.0 1.3e-21 76.5 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF1900) WD40 PF00400.27 OAJ26562.1 - 1.4e-05 24.8 5.0 0.028 14.3 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat MFS_1 PF07690.11 OAJ26563.1 - 9.2e-28 96.9 44.3 1.6e-26 92.9 26.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Myc_target_1 PF15179.1 OAJ26563.1 - 0.034 13.7 0.0 0.095 12.2 0.0 1.7 1 0 0 1 1 1 0 Myc target protein 1 DUF1049 PF06305.6 OAJ26563.1 - 0.14 11.6 0.1 0.14 11.6 0.1 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF1049) Mtr2 PF10429.4 OAJ26564.1 - 0.058 13.1 0.0 0.69 9.6 0.0 2.3 1 1 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 NTF2 PF02136.15 OAJ26564.1 - 0.1 12.9 0.0 1.7 9.0 0.0 2.7 2 1 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain Abhydrolase_5 PF12695.2 OAJ26566.1 - 4.9e-05 23.1 0.1 0.00014 21.6 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 OAJ26566.1 - 0.0038 16.8 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) IKI3 PF04762.7 OAJ26568.1 - 3.8e-236 786.2 0.0 4.6e-236 785.9 0.0 1.1 1 0 0 1 1 1 1 IKI3 family Se-cys_synth_N PF12390.3 OAJ26568.1 - 0.0084 16.1 0.9 0.0084 16.1 0.6 2.4 2 0 0 2 2 2 1 Selenocysteine synthase N terminal DUF342 PF03961.8 OAJ26568.1 - 0.3 9.4 0.1 0.55 8.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Nup35_RRM PF05172.8 OAJ26569.1 - 2.5e-06 27.1 0.0 5.6e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 OAJ26569.1 - 5.2e-05 22.9 0.0 9.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Peptidase_M24 PF00557.19 OAJ26570.1 - 1.2e-43 149.0 0.1 1.7e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3663 PF12404.3 OAJ26570.1 - 0.026 14.2 0.3 4.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Peptidase DUF4448 PF14610.1 OAJ26571.1 - 1.6e-07 30.9 0.0 2.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) RRM_6 PF14259.1 OAJ26572.1 - 1e-08 35.0 0.0 0.0016 18.3 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ26572.1 - 1.9e-08 33.8 1.1 0.0063 16.1 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1824 PF08854.5 OAJ26572.1 - 0.033 13.8 0.1 0.088 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) PCI PF01399.22 OAJ26573.1 - 1.2e-10 41.5 0.2 4.3e-10 39.8 0.1 2.0 1 0 0 1 1 1 1 PCI domain Peptidase_M15_2 PF05951.8 OAJ26573.1 - 0.15 11.5 6.6 0.68 9.3 0.0 3.6 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF882) Nol1_Nop2_Fmu PF01189.12 OAJ26574.1 - 4.9e-16 58.9 0.1 2.6e-10 40.1 0.0 2.7 2 1 0 2 2 2 2 NOL1/NOP2/sun family HWE_HK PF07536.9 OAJ26574.1 - 0.043 14.2 0.3 0.043 14.2 0.2 2.4 3 0 0 3 3 3 0 HWE histidine kinase Sas10_Utp3 PF04000.10 OAJ26575.1 - 4.4e-10 39.6 0.2 1e-09 38.4 0.1 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family RXT2_N PF08595.6 OAJ26575.1 - 0.14 11.9 11.6 0.064 13.0 2.4 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal RRN3 PF05327.6 OAJ26575.1 - 0.16 10.0 3.2 0.24 9.4 2.3 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AF1Q PF15017.1 OAJ26575.1 - 0.58 10.1 9.9 9.2 6.2 3.7 2.5 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator DUF3245 PF11595.3 OAJ26575.1 - 2.9 8.1 19.3 0.55 10.5 1.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) DUF4444 PF14563.1 OAJ26575.1 - 4.2 6.8 5.9 27 4.2 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4444) Nucleoplasmin PF03066.10 OAJ26575.1 - 4.9 6.6 17.3 1 8.8 7.1 2.4 2 0 0 2 2 2 0 Nucleoplasmin DUF159 PF02586.9 OAJ26576.1 - 7.8e-48 162.7 0.0 1.6e-47 161.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, COG2135 DUF1669 PF07894.7 OAJ26576.1 - 0.18 10.9 2.0 0.32 10.1 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) Amastin PF07344.6 OAJ26577.1 - 0.7 9.5 9.9 0.29 10.7 4.2 2.0 2 0 0 2 2 2 0 Amastin surface glycoprotein PMP22_Claudin PF00822.15 OAJ26577.1 - 4.8 6.8 9.6 0.27 10.8 2.4 1.9 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family LysM PF01476.15 OAJ26578.1 - 0.00016 21.5 0.0 0.00037 20.3 0.0 1.7 1 0 0 1 1 1 1 LysM domain DTHCT PF08070.6 OAJ26578.1 - 0.11 13.1 3.4 0.43 11.2 2.4 2.0 1 0 0 1 1 1 0 DTHCT (NUC029) region Zn_clus PF00172.13 OAJ26579.1 - 0.00016 21.4 11.6 0.00016 21.4 8.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.1 OAJ26579.1 - 0.00022 21.5 0.0 0.00078 19.7 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 OAJ26579.1 - 0.00028 20.6 0.0 0.00069 19.3 0.0 1.7 2 0 0 2 2 2 1 PAS fold SNF2_N PF00176.18 OAJ26580.1 - 3.4e-69 232.9 0.5 5e-69 232.3 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 OAJ26580.1 - 4.2e-16 59.0 0.6 4.2e-16 59.0 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 OAJ26580.1 - 4.8e-14 51.9 0.0 1.3e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 OAJ26580.1 - 4.5e-13 48.6 1.0 2.5e-08 33.4 0.2 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain TFIIIC_delta PF12657.2 OAJ26581.1 - 1.5e-08 34.5 0.2 3.8e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 OAJ26581.1 - 0.0028 17.5 0.7 0.0062 16.4 0.5 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TRAPP PF04051.11 OAJ26582.1 - 2.2e-31 108.4 0.0 2.6e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF1752 PF08550.5 OAJ26583.1 - 2.2e-10 39.9 3.9 4.6e-10 38.8 2.7 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RVT_3 PF13456.1 OAJ26584.1 - 0.032 14.0 0.0 0.093 12.5 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase-like WD40 PF00400.27 OAJ26585.1 - 1e-27 94.9 10.3 2.1e-07 30.5 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Semialdhyde_dhC PF02774.13 OAJ26589.1 - 1.7e-42 145.3 0.1 2.9e-42 144.6 0.0 1.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 OAJ26589.1 - 2.5e-28 98.8 0.0 5.1e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 OAJ26589.1 - 0.00032 20.6 0.0 0.00081 19.3 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.15 OAJ26589.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.11 OAJ26589.1 - 0.065 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Ribosomal_L28 PF00830.14 OAJ26590.1 - 4.6e-22 77.6 0.1 7.4e-22 76.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L28 family Brix PF04427.13 OAJ26591.1 - 1.3e-48 165.1 0.1 1.8e-48 164.7 0.1 1.2 1 0 0 1 1 1 1 Brix domain DUF2517 PF10725.4 OAJ26591.1 - 0.0086 15.7 0.1 0.18 11.5 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2517) DUF4128 PF13554.1 OAJ26591.1 - 0.024 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function Per1 PF04080.8 OAJ26592.1 - 6e-91 304.5 0.0 1.1e-90 303.7 0.0 1.4 1 1 0 1 1 1 1 Per1-like Arf PF00025.16 OAJ26593.1 - 2.6e-67 225.4 0.1 3e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 OAJ26593.1 - 4.8e-12 45.2 2.9 9e-07 27.9 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 OAJ26593.1 - 2.7e-09 36.5 0.0 3.6e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 OAJ26593.1 - 3e-08 33.0 0.0 3.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 OAJ26593.1 - 3.1e-07 30.3 0.0 4.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAJ26593.1 - 9.8e-07 29.2 0.0 1.4e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 OAJ26593.1 - 9.8e-07 28.2 0.0 1.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 OAJ26593.1 - 6.3e-05 22.4 0.0 0.0035 16.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 OAJ26593.1 - 0.022 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 OAJ26593.1 - 0.033 15.0 0.2 0.13 13.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAJ26593.1 - 0.034 14.4 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 OAJ26593.1 - 0.04 13.6 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 OAJ26593.1 - 0.091 12.0 0.1 0.27 10.5 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B BRE1 PF08647.6 OAJ26594.1 - 1.1e-15 57.3 10.2 1.1e-15 57.3 7.1 7.1 5 3 3 8 8 8 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 OAJ26594.1 - 7.8e-08 32.2 12.5 1.4e-07 31.4 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ26594.1 - 1.1e-06 28.2 13.9 1.9e-06 27.4 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 OAJ26594.1 - 2.7e-06 27.0 2.9 4.9e-06 26.2 2.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 OAJ26594.1 - 1.8e-05 24.3 12.1 3.6e-05 23.4 8.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAJ26594.1 - 1.9e-05 24.2 9.4 3.6e-05 23.3 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ26594.1 - 0.00021 21.0 9.9 0.00039 20.1 6.9 1.5 1 0 0 1 1 1 1 Ring finger domain Fez1 PF06818.10 OAJ26594.1 - 0.00091 19.3 17.1 0.00091 19.3 11.9 5.1 4 1 1 5 5 3 1 Fez1 Seryl_tRNA_N PF02403.17 OAJ26594.1 - 0.0086 16.0 4.8 0.0086 16.0 3.3 8.2 5 3 4 10 10 9 1 Seryl-tRNA synthetase N-terminal domain zf-ribbon_3 PF13248.1 OAJ26594.1 - 0.03 13.5 0.2 0.07 12.3 0.2 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zf-rbx1 PF12678.2 OAJ26594.1 - 0.056 13.5 5.4 0.11 12.6 3.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 OAJ26594.1 - 0.06 13.2 10.8 0.037 13.9 6.1 1.7 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.6 OAJ26594.1 - 0.17 11.7 5.1 0.4 10.5 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) UPF0547 PF10571.4 OAJ26594.1 - 0.26 11.0 1.9 0.55 9.9 1.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-RING_UBOX PF13445.1 OAJ26594.1 - 0.29 10.8 6.0 0.76 9.5 4.1 1.8 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.2 OAJ26594.1 - 0.44 10.4 6.2 1.1 9.1 4.3 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-Nse PF11789.3 OAJ26594.1 - 0.72 9.4 4.8 1.6 8.2 3.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Nsp1_C PF05064.8 OAJ26594.1 - 1.5 8.4 18.4 1.7 8.2 4.7 4.1 4 2 0 4 4 4 0 Nsp1-like C-terminal region FlaC_arch PF05377.6 OAJ26594.1 - 3.2 7.7 21.7 2.2 8.2 0.8 6.6 7 1 1 8 8 7 0 Flagella accessory protein C (FlaC) zf-FCS PF06467.9 OAJ26594.1 - 3.3 7.4 6.6 14 5.4 2.9 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-RING_4 PF14570.1 OAJ26594.1 - 7.8 6.1 9.9 24 4.6 6.9 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain STAT1_TAZ2bind PF12162.3 OAJ26595.1 - 0.0037 16.6 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 STAT1 TAZ2 binding domain DUF1690 PF07956.6 OAJ26596.1 - 9.1e-14 51.6 2.9 9.1e-14 51.6 2.0 2.1 2 0 0 2 2 2 1 Protein of Unknown function (DUF1690) Apolipoprotein PF01442.13 OAJ26596.1 - 0.0095 15.4 6.5 1.5 8.2 0.0 2.5 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain Rootletin PF15035.1 OAJ26596.1 - 0.025 14.5 10.9 0.52 10.2 7.6 2.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion GIT1_C PF12205.3 OAJ26596.1 - 0.076 12.8 2.2 0.081 12.7 0.3 2.0 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Tape_meas_lam_C PF09718.5 OAJ26596.1 - 0.65 9.9 10.0 0.24 11.3 1.0 3.2 2 1 1 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF883 PF05957.8 OAJ26596.1 - 1.5 9.2 19.3 0.48 10.8 1.8 3.3 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Ndc1_Nup PF09531.5 OAJ26596.1 - 1.9 6.7 6.8 2 6.7 4.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup YtxH PF12732.2 OAJ26596.1 - 3.4 8.1 21.0 5.9 7.3 7.9 3.7 2 2 0 2 2 2 0 YtxH-like protein FlaC_arch PF05377.6 OAJ26596.1 - 3.6 7.5 4.9 5.7 6.9 0.1 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 OAJ26596.1 - 6.3 7.2 8.6 7.6 6.9 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) COG2 PF06148.6 OAJ26596.1 - 6.5 6.6 13.7 11 5.8 1.0 3.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_S64 PF08192.6 OAJ26596.1 - 9.5 4.4 12.6 11 4.2 8.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 TP_methylase PF00590.15 OAJ26597.1 - 3e-14 53.2 0.5 1.1e-13 51.3 0.1 2.1 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases FTR1 PF03239.9 OAJ26598.1 - 1.5e-54 185.0 4.9 1.5e-34 119.3 2.0 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family Herpes_glycop PF01528.11 OAJ26598.1 - 0.039 12.6 0.1 0.15 10.7 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus glycoprotein M Cu-oxidase PF00394.17 OAJ26599.1 - 1.1e-35 122.8 0.1 2.3e-32 112.0 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAJ26599.1 - 1.7e-35 121.5 5.4 3.8e-35 120.4 1.8 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 OAJ26599.1 - 2.8e-15 56.1 7.3 1.4e-12 47.3 1.0 3.9 4 1 0 4 4 4 2 Multicopper oxidase Clp1 PF06807.9 OAJ26600.1 - 1e-18 67.8 0.0 1.1e-17 64.4 0.0 2.1 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 OAJ26600.1 - 0.0071 16.0 0.0 0.018 14.7 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 OAJ26600.1 - 0.0078 16.1 0.0 0.019 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 OAJ26600.1 - 0.024 15.1 0.1 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 OAJ26600.1 - 0.04 13.8 0.0 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase SurE PF01975.12 OAJ26601.1 - 2.8e-39 134.4 0.0 6.6e-39 133.2 0.0 1.6 1 1 0 1 1 1 1 Survival protein SurE Glyco_trans_4_4 PF13579.1 OAJ26601.1 - 0.028 14.5 0.1 0.088 12.9 0.0 2.0 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain DUF2970 PF11174.3 OAJ26602.1 - 0.09 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) LisH PF08513.6 OAJ26603.1 - 0.00035 20.2 0.0 0.00067 19.3 0.0 1.5 1 0 0 1 1 1 1 LisH Vps51 PF08700.6 OAJ26604.1 - 8.5e-23 80.0 0.1 1.8e-22 78.9 0.0 1.5 1 1 1 2 2 2 1 Vps51/Vps67 COG5 PF10392.4 OAJ26604.1 - 0.00085 19.2 0.4 0.0012 18.8 0.2 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.7 OAJ26604.1 - 0.0019 16.7 0.5 0.0025 16.3 0.3 1.1 1 0 0 1 1 1 1 Dor1-like family DUF3086 PF11285.3 OAJ26604.1 - 0.013 14.2 0.3 0.017 13.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) FlgN PF05130.7 OAJ26604.1 - 0.075 13.2 0.3 0.11 12.7 0.2 1.2 1 0 0 1 1 1 0 FlgN protein Vps52 PF04129.7 OAJ26604.1 - 0.15 10.5 0.1 0.18 10.2 0.1 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family Chorion_3 PF05387.6 OAJ26604.1 - 0.58 9.5 4.3 0.77 9.1 3.0 1.3 1 0 0 1 1 1 0 Chorion family 3 Patched PF02460.13 OAJ26605.1 - 2.1e-63 214.5 10.0 2e-39 135.2 0.2 2.9 3 1 0 3 3 3 2 Patched family Sterol-sensing PF12349.3 OAJ26605.1 - 4.4e-43 146.3 13.6 2.6e-23 82.1 0.2 3.2 4 0 0 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 OAJ26605.1 - 0.00032 18.2 1.2 0.00048 17.7 0.8 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SNARE PF05739.14 OAJ26608.1 - 5.3e-17 61.2 1.0 5.3e-17 61.2 0.7 2.2 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.1 OAJ26608.1 - 3.4e-11 43.0 3.6 5.6e-11 42.3 1.3 2.1 2 1 0 2 2 2 1 Syntaxin-like protein MCPsignal PF00015.16 OAJ26608.1 - 0.013 15.0 0.9 0.013 15.0 0.6 2.0 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin PF00804.20 OAJ26608.1 - 0.51 10.5 5.4 0.29 11.3 1.0 2.5 2 1 0 2 2 2 0 Syntaxin Peptidase_S8 PF00082.17 OAJ26609.1 - 9.9e-48 162.7 12.2 1.6e-47 162.0 8.5 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 OAJ26609.1 - 4.6e-12 46.3 0.2 1.2e-11 45.0 0.2 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 AA_permease_2 PF13520.1 OAJ26611.1 - 6.5e-62 209.4 38.9 8.3e-62 209.0 27.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAJ26611.1 - 7.5e-30 103.6 35.2 1.1e-29 103.0 24.4 1.2 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 OAJ26612.1 - 1.1e-52 178.8 0.0 6.8e-34 117.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ26612.1 - 8.1e-23 80.8 0.1 1.4e-15 57.1 0.0 2.7 2 1 1 3 3 3 2 Protein tyrosine kinase APH PF01636.18 OAJ26612.1 - 0.002 17.8 1.4 0.054 13.2 0.1 2.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ26612.1 - 0.038 12.9 0.0 0.18 10.7 0.0 2.0 2 0 0 2 2 2 0 Kinase-like DnaJ PF00226.26 OAJ26613.1 - 2.8e-18 65.4 0.1 9.6e-18 63.6 0.0 2.0 1 0 0 1 1 1 1 DnaJ domain AAA_23 PF13476.1 OAJ26613.1 - 0.1 12.9 8.1 0.18 12.1 5.6 1.3 1 0 0 1 1 1 0 AAA domain Ribonuc_2-5A PF06479.7 OAJ26615.1 - 6.3e-43 145.6 0.0 1.1e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 OAJ26615.1 - 9.4e-42 142.9 0.0 1.5e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ26615.1 - 5.6e-20 71.5 0.0 3.2e-19 69.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 OAJ26615.1 - 0.0023 17.3 0.0 0.025 14.1 0.0 2.5 2 0 0 2 2 2 1 PQQ enzyme repeat Kdo PF06293.9 OAJ26615.1 - 0.0042 16.1 0.0 0.0077 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 OAJ26615.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Nucleoplasmin PF03066.10 OAJ26615.1 - 0.25 10.8 2.7 0.22 11.0 0.2 2.0 2 0 0 2 2 2 0 Nucleoplasmin Nucleoporin_C PF03177.9 OAJ26616.1 - 8.2e-78 262.3 8.2 1.1e-77 261.9 5.7 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 OAJ26616.1 - 3.6e-54 184.1 0.1 5.7e-54 183.4 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like ArsB PF02040.10 OAJ26617.1 - 1.3e-16 60.6 19.5 2.2e-09 36.7 4.7 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein SPA PF08616.5 OAJ26618.1 - 7.1e-46 154.5 0.0 5.2e-34 116.3 0.0 2.6 3 0 0 3 3 3 2 Stabilization of polarity axis Afi1 PF07792.7 OAJ26618.1 - 7.8e-43 145.9 0.0 1.2e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.4 OAJ26618.1 - 1.8e-09 36.6 0.0 0.00044 18.8 0.0 4.4 3 2 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.4 OAJ26618.1 - 0.04 13.1 0.0 4.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) EF_TS PF00889.14 OAJ26619.1 - 1.6e-14 53.7 0.0 6.8e-13 48.4 0.0 2.9 3 0 0 3 3 3 1 Elongation factor TS FUSC_2 PF13515.1 OAJ26621.1 - 2e-15 56.8 16.9 2e-15 56.8 11.7 3.0 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 OAJ26621.1 - 1.7e-13 49.9 0.0 3.7e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Aluminium activated malate transporter DUF2422 PF10337.4 OAJ26621.1 - 7.5e-11 41.4 6.9 7.5e-11 41.4 4.8 4.5 4 1 0 4 4 4 1 Protein of unknown function (DUF2422) FUSC PF04632.7 OAJ26621.1 - 1.2e-08 33.9 21.6 1.2e-08 33.9 15.0 3.5 3 2 0 3 3 3 1 Fusaric acid resistance protein family DUF939 PF06081.6 OAJ26621.1 - 2.8e-07 30.4 8.1 1e-06 28.6 5.6 2.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF939) DUF2421 PF10334.4 OAJ26621.1 - 4.7e-05 23.1 0.8 0.00019 21.1 0.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) MbeB_N PF04837.7 OAJ26621.1 - 0.23 11.6 3.1 0.31 11.1 0.1 2.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Peptidase_M28 PF04389.12 OAJ26622.1 - 5.6e-31 107.6 0.0 9e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 OAJ26622.1 - 0.0011 18.5 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 SMC_N PF02463.14 OAJ26623.1 - 3.8e-21 75.3 0.0 7.5e-21 74.3 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAJ26623.1 - 3.1e-14 53.7 12.0 3.1e-14 53.7 8.3 5.4 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 OAJ26623.1 - 4.6e-06 26.8 0.0 3.3e-05 24.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 OAJ26623.1 - 0.00013 21.4 0.3 0.0011 18.4 0.0 2.6 3 1 1 4 4 4 1 P-loop containing region of AAA domain AAA_22 PF13401.1 OAJ26623.1 - 0.079 13.1 3.4 1.3 9.2 0.0 3.7 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.22 OAJ26623.1 - 0.079 13.2 0.0 0.079 13.2 0.0 5.1 3 2 0 3 3 3 0 ABC transporter AAA_13 PF13166.1 OAJ26623.1 - 0.094 11.1 62.4 0.096 11.1 9.5 4.7 3 2 1 4 4 4 0 AAA domain AAA_19 PF13245.1 OAJ26623.1 - 0.1 12.3 0.1 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Surfac_D-trimer PF09006.6 OAJ26623.1 - 8.8 6.1 10.6 5.5 6.8 0.6 4.1 3 1 1 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation WD40 PF00400.27 OAJ26624.1 - 4e-11 42.3 5.3 0.14 12.1 0.1 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat PQQ_3 PF13570.1 OAJ26624.1 - 0.0048 17.1 1.4 6 7.2 0.0 4.6 5 0 0 5 5 5 1 PQQ-like domain PQQ_2 PF13360.1 OAJ26624.1 - 0.0063 15.9 0.1 0.099 12.0 0.0 2.3 2 0 0 2 2 2 1 PQQ-like domain Med3 PF11593.3 OAJ26624.1 - 0.58 9.3 10.3 0.057 12.6 2.4 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Fructosamin_kin PF03881.9 OAJ26633.1 - 4.9e-60 202.9 0.0 7.9e-60 202.2 0.0 1.3 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 OAJ26633.1 - 5.9e-07 29.4 0.0 9.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sugar_tr PF00083.19 OAJ26634.1 - 2.9e-71 240.4 19.2 4.1e-67 226.7 7.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ26634.1 - 1.4e-15 56.8 22.8 1.4e-15 56.8 15.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily PAH PF02671.16 OAJ26635.1 - 7.4e-44 147.1 3.3 5.2e-18 64.4 0.6 3.4 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 OAJ26635.1 - 3e-38 129.6 0.2 3e-38 129.6 0.1 2.5 3 0 0 3 3 3 1 Sin3 family co-repressor Metallophos PF00149.23 OAJ26636.1 - 2.7e-43 147.6 0.1 3.4e-43 147.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DAO PF01266.19 OAJ26637.1 - 7.4e-14 51.4 3.4 5.9e-11 41.8 0.0 2.8 1 1 2 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAJ26637.1 - 0.0038 17.5 0.0 0.0074 16.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase RFX_DNA_binding PF02257.10 OAJ26638.1 - 3.2e-22 78.4 0.2 7.2e-22 77.3 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain HPHLAWLY PF14925.1 OAJ26639.1 - 0.37 8.7 10.6 0.85 7.5 7.4 1.5 1 0 0 1 1 1 0 Domain of unknown function Glyco_hydro_47 PF01532.15 OAJ26640.1 - 1.2e-141 472.4 0.0 1.5e-141 472.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Bystin PF05291.6 OAJ26641.1 - 5.3e-111 370.3 0.0 7.7e-111 369.8 0.0 1.1 1 0 0 1 1 1 1 Bystin Daxx PF03344.10 OAJ26641.1 - 0.65 8.4 8.5 0.9 7.9 5.9 1.1 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 OAJ26641.1 - 2.8 7.5 11.1 5 6.7 7.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Shugoshin_C PF07557.6 OAJ26642.1 - 7e-21 73.3 23.8 3.8e-11 42.2 3.4 4.1 3 0 0 3 3 3 3 Shugoshin C terminus Vac_ImportDeg PF09783.4 OAJ26644.1 - 1e-52 178.2 0.0 9.1e-49 165.3 0.0 2.2 2 0 0 2 2 2 2 Vacuolar import and degradation protein Methyltransf_23 PF13489.1 OAJ26645.1 - 1.5e-11 44.2 0.0 3.2e-11 43.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ26645.1 - 3.3e-10 40.3 0.0 1.1e-09 38.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ26645.1 - 7.1e-09 36.0 0.0 1.4e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ26645.1 - 2.9e-05 23.6 0.0 6.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ26645.1 - 0.0054 17.3 0.0 0.018 15.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ26645.1 - 0.018 15.3 0.0 0.041 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 OAJ26646.1 - 2.1e-09 36.9 4.9 0.00011 21.8 0.1 6.8 7 0 0 7 7 7 2 WD domain, G-beta repeat Sigma70_ner PF04546.8 OAJ26646.1 - 0.63 9.6 2.7 2.2 7.8 1.0 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region FAM176 PF14851.1 OAJ26646.1 - 4.3 6.9 4.5 4.9 6.8 0.7 2.4 2 0 0 2 2 2 0 FAM176 family AA_kinase PF00696.23 OAJ26647.1 - 6.4e-30 104.4 0.4 8.1e-30 104.1 0.3 1.1 1 0 0 1 1 1 1 Amino acid kinase family H_kinase_N PF12282.3 OAJ26647.1 - 0.09 12.3 0.1 10 5.7 0.0 2.2 2 0 0 2 2 2 0 Signal transduction histidine kinase Dynamin_N PF00350.18 OAJ26648.1 - 1.4e-40 138.8 0.0 2.7e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 OAJ26648.1 - 0.00017 20.4 0.0 0.00049 18.9 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 OAJ26648.1 - 0.0013 18.7 0.0 0.0044 16.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAJ26648.1 - 0.0064 16.9 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Peptidase_S58 PF03576.9 OAJ26648.1 - 0.072 12.2 5.3 0.043 13.0 2.3 1.6 2 0 0 2 2 2 0 Peptidase family S58 GTP_EFTU PF00009.22 OAJ26648.1 - 0.1 12.0 0.1 5.2 6.4 0.1 3.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_21 PF13304.1 OAJ26648.1 - 0.2 11.5 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Vps52 PF04129.7 OAJ26649.1 - 2.6e-40 138.4 0.0 3.5e-37 128.1 0.0 2.3 2 0 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.4 OAJ26649.1 - 7e-05 21.1 0.0 0.0001 20.6 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 PPP4R2 PF09184.6 OAJ26649.1 - 0.0095 15.5 3.2 0.02 14.4 2.2 1.4 1 0 0 1 1 1 1 PPP4R2 Daxx PF03344.10 OAJ26649.1 - 0.087 11.3 4.9 0.15 10.5 3.4 1.3 1 0 0 1 1 1 0 Daxx Family GP41 PF00517.12 OAJ26649.1 - 0.27 10.7 0.1 0.45 10.0 0.1 1.3 1 0 0 1 1 1 0 Retroviral envelope protein Cwf_Cwc_15 PF04889.7 OAJ26649.1 - 0.89 9.2 13.6 3.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 OAJ26649.1 - 0.92 9.0 12.8 1.5 8.2 8.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 OAJ26649.1 - 4 6.0 17.0 8.3 5.0 11.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 OAJ26649.1 - 6.3 4.5 11.5 0.65 7.8 4.9 1.5 2 0 0 2 2 2 0 Nop14-like family RXT2_N PF08595.6 OAJ26649.1 - 6.7 6.5 8.5 16 5.3 5.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.5 OAJ26649.1 - 7 6.9 18.9 3 8.1 10.8 2.0 2 0 0 2 2 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 OAJ26649.1 - 7 6.2 11.8 1.8 8.1 5.6 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region NOA36 PF06524.7 OAJ26649.1 - 8.5 5.5 10.2 13 4.9 7.1 1.1 1 0 0 1 1 1 0 NOA36 protein EHN PF06441.7 OAJ26651.1 - 2.9e-23 81.9 0.1 5.6e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 OAJ26651.1 - 2.7e-10 40.1 0.0 5e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ26651.1 - 2.2e-08 34.2 3.4 2.2e-08 34.2 2.3 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family NAD_binding_10 PF13460.1 OAJ26651.1 - 4.4e-06 26.8 0.0 6.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding LRR_4 PF12799.2 OAJ26652.1 - 2.2e-14 52.6 8.9 1.3e-05 24.7 2.0 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ26652.1 - 1.3e-13 50.4 10.3 1.7e-08 34.1 3.4 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 OAJ26652.1 - 1.3e-05 24.5 13.5 0.82 9.9 0.1 5.7 4 1 1 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 OAJ26652.1 - 0.37 11.1 17.1 8.8 7.0 0.2 5.6 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 OAJ26652.1 - 2.1 8.6 10.4 11 6.3 0.1 4.5 4 1 1 5 5 5 0 Leucine Rich repeat MFS_1 PF07690.11 OAJ26653.1 - 1.1e-22 80.2 30.0 1.1e-17 63.8 7.9 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 OAJ26653.1 - 1e-07 30.8 17.8 5.9e-06 25.0 2.6 2.7 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like TAP42 PF04177.7 OAJ26653.1 - 0.072 12.0 1.1 0.14 11.1 0.8 1.4 1 0 0 1 1 1 0 TAP42-like family MFS_3 PF05977.8 OAJ26653.1 - 0.16 10.0 0.0 0.16 10.0 0.0 2.8 3 0 0 3 3 3 0 Transmembrane secretion effector DJ-1_PfpI PF01965.19 OAJ26654.1 - 4.5e-26 91.0 0.0 7.2e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 OAJ26654.1 - 5.3e-17 61.0 0.0 9.7e-17 60.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DEAD PF00270.24 OAJ26655.1 - 2.9e-28 98.4 0.0 4.9e-13 48.9 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ26655.1 - 9.9e-21 73.4 0.1 5.4e-20 71.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ26655.1 - 0.00066 19.5 0.2 0.0057 16.5 0.0 2.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Cmc1 PF08583.5 OAJ26656.1 - 1.5e-17 63.0 1.3 2.2e-17 62.5 0.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 OAJ26656.1 - 0.081 12.9 0.4 14 5.7 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 OAJ26656.1 - 0.91 9.5 3.2 5.1 7.1 2.3 2.2 1 1 1 2 2 2 0 CHCH domain Tfb4 PF03850.9 OAJ26657.1 - 5.9e-38 130.7 13.8 2.2e-19 69.7 5.6 3.0 1 1 1 2 2 2 2 Transcription factor Tfb4 CAF1A PF12253.3 OAJ26659.1 - 1.7e-21 76.1 9.8 1.7e-21 76.1 6.8 3.5 4 1 0 4 4 4 1 Chromatin assembly factor 1 subunit A Borrelia_P83 PF05262.6 OAJ26659.1 - 0.036 12.3 35.2 0.062 11.5 24.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein G-7-MTase PF12803.2 OAJ26659.1 - 3.7 6.6 10.4 1.4 8.0 5.4 1.5 1 1 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Sigma70_ner PF04546.8 OAJ26660.1 - 0.3 10.6 3.9 0.52 9.8 2.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 OAJ26660.1 - 2.1 8.6 15.6 4.8 7.4 10.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.7 OAJ26660.1 - 3.4 5.4 7.8 4.3 5.1 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 OAJ26660.1 - 4.2 6.3 9.1 9.9 5.1 6.3 1.6 1 0 0 1 1 1 0 BUD22 NPR2 PF06218.6 OAJ26661.1 - 2.9e-105 352.4 3.3 3.6e-60 203.8 0.2 4.2 3 1 0 3 3 3 3 Nitrogen permease regulator 2 NPR3 PF03666.8 OAJ26661.1 - 0.0033 16.0 4.2 0.065 11.7 0.0 2.6 2 1 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 GAS2 PF02187.12 OAJ26662.1 - 2.5e-08 33.5 0.0 6.3e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Gp-FAR-1 PF05823.7 OAJ26662.1 - 0.11 12.5 7.0 11 5.9 0.0 4.6 4 1 0 4 4 4 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FCH PF00611.18 OAJ26662.1 - 0.17 12.1 3.9 6.4 7.0 0.3 4.1 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain zf-MYND PF01753.13 OAJ26663.1 - 3.5e-10 39.5 13.0 3.5e-10 39.5 9.0 2.7 2 1 1 3 3 3 1 MYND finger SET PF00856.23 OAJ26663.1 - 4.8e-06 26.9 0.0 1.4e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 SET domain DNA_RNApol_7kD PF03604.8 OAJ26663.1 - 0.46 9.9 5.0 10 5.6 0.8 3.1 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-Mss51 PF13824.1 OAJ26663.1 - 8.1 6.3 10.0 3.1 7.7 2.7 2.9 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 ATP_bind_1 PF03029.12 OAJ26664.1 - 1.9e-81 273.0 0.0 3.1e-80 269.1 0.0 1.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 OAJ26664.1 - 7.8e-08 31.9 0.0 2e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 OAJ26664.1 - 1.8e-05 25.5 0.1 6.8e-05 23.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 OAJ26664.1 - 0.00021 20.8 0.0 0.00064 19.2 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 OAJ26664.1 - 0.00033 20.7 1.7 0.006 16.7 0.0 2.6 1 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 OAJ26664.1 - 0.00084 18.8 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_33 PF13671.1 OAJ26664.1 - 0.00087 19.1 0.1 0.0023 17.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 OAJ26664.1 - 0.0022 17.1 0.0 0.0055 15.8 0.0 1.6 1 1 0 1 1 1 1 KaiC AAA_16 PF13191.1 OAJ26664.1 - 0.0027 17.7 0.0 0.029 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 OAJ26664.1 - 0.0041 16.5 0.0 0.0074 15.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_29 PF13555.1 OAJ26664.1 - 0.0041 16.6 0.0 0.0073 15.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.1 OAJ26664.1 - 0.0058 16.2 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 OAJ26664.1 - 0.009 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 OAJ26664.1 - 0.011 15.4 0.0 0.032 13.9 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 OAJ26664.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein T2SE PF00437.15 OAJ26664.1 - 0.015 14.1 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein GTP_EFTU PF00009.22 OAJ26664.1 - 0.019 14.3 0.0 0.25 10.7 0.0 2.4 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ26664.1 - 0.022 14.7 0.0 0.058 13.3 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 OAJ26664.1 - 0.036 14.3 0.1 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain MipZ PF09140.6 OAJ26664.1 - 0.037 13.1 0.0 0.3 10.1 0.0 2.2 1 1 0 1 1 1 0 ATPase MipZ RNA_helicase PF00910.17 OAJ26664.1 - 0.057 13.5 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.5 OAJ26664.1 - 0.061 12.5 0.0 0.29 10.3 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_25 PF13481.1 OAJ26664.1 - 0.066 12.5 0.2 0.52 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 OAJ26664.1 - 0.068 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain CobU PF02283.11 OAJ26664.1 - 0.084 12.2 0.0 0.29 10.5 0.0 1.9 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA PF00004.24 OAJ26664.1 - 0.085 13.0 0.0 1.1 9.5 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 OAJ26664.1 - 0.097 12.5 0.0 0.44 10.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain BTB PF00651.26 OAJ26666.1 - 0.002 18.0 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain AlaDh_PNT_N PF05222.10 OAJ26667.1 - 1.5e-27 96.2 0.0 2.4e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 OAJ26667.1 - 1e-07 31.6 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiC-associated PF13667.1 OAJ26667.1 - 0.075 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 ThiC-associated domain Cyclin_N PF00134.18 OAJ26668.1 - 0.00068 19.2 0.1 0.00068 19.2 0.1 2.9 4 0 0 4 4 4 1 Cyclin, N-terminal domain TMEM237 PF15383.1 OAJ26668.1 - 0.73 8.9 3.2 1.2 8.2 2.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 AAA_12 PF13087.1 OAJ26674.1 - 1.2e-45 155.3 0.0 1.9e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAJ26674.1 - 8.6e-41 140.0 0.0 2.1e-40 138.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ26674.1 - 1.6e-12 46.9 3.2 5.7e-12 45.2 1.4 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 OAJ26674.1 - 2.7e-08 33.6 2.6 7.8e-07 28.8 0.3 3.0 3 0 0 3 3 3 1 AAA domain UvrD-helicase PF00580.16 OAJ26674.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 OAJ26674.1 - 0.00026 20.5 0.1 4 6.8 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 OAJ26674.1 - 0.086 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 OAJ26674.1 - 0.45 9.4 0.4 1.9 7.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Mur_ligase_M PF08245.7 OAJ26675.1 - 0.0012 18.8 0.0 0.003 17.6 0.0 1.5 1 1 0 1 1 1 1 Mur ligase middle domain OTU PF02338.14 OAJ26676.1 - 1.3e-15 58.0 0.0 2.3e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 OAJ26676.1 - 0.02 14.2 0.0 0.81 8.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase C65 Otubain AFG1_ATPase PF03969.11 OAJ26677.1 - 0.14 10.9 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase PTS_EIIA_2 PF00359.17 OAJ26678.1 - 0.042 13.5 0.1 0.047 13.4 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Med9 PF07544.8 OAJ26679.1 - 0.013 15.1 1.8 0.44 10.3 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 cwf21 PF08312.7 OAJ26679.1 - 0.016 15.0 1.3 0.02 14.7 0.1 1.7 2 0 0 2 2 2 0 cwf21 domain MscS_porin PF12795.2 OAJ26679.1 - 0.051 12.8 3.3 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Prefoldin_2 PF01920.15 OAJ26679.1 - 0.14 11.9 1.1 5.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit Choline_transpo PF04515.7 OAJ26680.1 - 3.3e-25 88.5 9.1 9.4e-12 44.3 0.0 3.4 3 0 0 3 3 3 3 Plasma-membrane choline transporter SDA1 PF05285.7 OAJ26680.1 - 0.75 9.0 14.1 1.4 8.1 9.8 1.3 1 0 0 1 1 1 0 SDA1 LIP PF03583.9 OAJ26681.1 - 4.8e-49 167.1 0.1 8.5e-49 166.2 0.1 1.3 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 OAJ26681.1 - 3.5e-07 30.0 0.1 8.4e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ26681.1 - 9.9e-07 28.8 0.0 2.3e-06 27.6 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ26681.1 - 0.00086 18.5 0.6 0.042 13.0 0.0 2.5 2 1 0 2 2 2 1 Prolyl oligopeptidase family Cutinase PF01083.17 OAJ26681.1 - 0.081 12.6 0.3 0.17 11.5 0.2 1.5 1 0 0 1 1 1 0 Cutinase GPI-anchored PF10342.4 OAJ26682.1 - 1.9e-10 41.1 2.5 3.5e-10 40.2 1.7 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cauli_VI PF01693.11 OAJ26683.1 - 1e-16 60.6 4.0 1.1e-10 41.3 1.2 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin Sulfatase PF00884.18 OAJ26683.1 - 0.06 12.5 1.0 0.076 12.1 0.7 1.3 1 0 0 1 1 1 0 Sulfatase Phage_min_tail PF05939.8 OAJ26683.1 - 0.11 12.5 0.7 5.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Phage minor tail protein Cauli_VI PF01693.11 OAJ26684.1 - 6.4e-16 58.1 1.0 6.7e-16 58.0 0.2 1.4 2 0 0 2 2 2 1 Caulimovirus viroplasmin BSD PF03909.12 OAJ26686.1 - 3.2e-15 55.6 0.0 9.7e-11 41.2 0.0 2.6 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 OAJ26686.1 - 0.00025 20.6 0.0 0.00066 19.2 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF4632 PF15451.1 OAJ26686.1 - 5.4 7.0 7.2 4.5 7.2 1.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4632) Med15 PF09606.5 OAJ26687.1 - 4e-06 25.3 7.8 4e-06 25.3 5.4 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal FCP1_C PF09309.5 OAJ26687.1 - 0.0061 15.9 6.2 0.01 15.1 4.3 1.3 1 0 0 1 1 1 1 FCP1, C-terminal DUF3371 PF11851.3 OAJ26687.1 - 0.065 13.9 8.4 0.054 14.1 4.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) PAT1 PF09770.4 OAJ26687.1 - 1.3 7.1 15.0 2.2 6.3 10.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF853 PF05872.7 OAJ26687.1 - 1.7 6.9 6.7 2.5 6.3 4.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF4557 PF15101.1 OAJ26687.1 - 2.1 8.1 10.3 3.8 7.3 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DivIC PF04977.10 OAJ26687.1 - 2.3 7.7 11.7 4.8 6.7 8.1 1.5 1 0 0 1 1 1 0 Septum formation initiator FLO_LFY PF01698.11 OAJ26687.1 - 5.7 5.6 8.1 20 3.8 5.8 1.6 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF788 PF05620.6 OAJ26687.1 - 9.9 5.9 9.5 40 4.0 6.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF788) Asp PF00026.18 OAJ26689.1 - 9e-44 149.9 0.0 2.7e-43 148.4 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 OAJ26689.1 - 0.0003 21.2 0.3 0.038 14.4 0.1 2.6 2 0 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.1 OAJ26689.1 - 0.00047 20.1 2.4 0.004 17.1 1.7 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal DUF2673 PF10880.3 OAJ26689.1 - 0.086 12.8 0.1 0.24 11.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) TFIIA PF03153.8 OAJ26690.1 - 0.059 13.2 15.5 0.33 10.8 5.7 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit DUF4017 PF13209.1 OAJ26690.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) DUF2933 PF11666.3 OAJ26691.1 - 0.29 10.6 0.0 0.29 10.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2933) CFEM PF05730.6 OAJ26691.1 - 0.37 10.6 5.5 0.58 10.0 3.3 1.8 1 1 0 1 1 1 0 CFEM domain Agouti PF05039.7 OAJ26691.1 - 0.4 11.0 3.8 0.83 10.0 0.5 2.2 2 0 0 2 2 2 0 Agouti protein Vps35 PF03635.12 OAJ26692.1 - 0 1099.7 0.0 0 1099.5 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RRM_1 PF00076.17 OAJ26692.1 - 1.2e-20 72.8 0.0 2.3e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ26692.1 - 3.1e-15 55.8 0.0 8.6e-15 54.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ26692.1 - 7.8e-13 48.0 0.0 2e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VHS PF00790.14 OAJ26693.1 - 1.3e-19 70.2 0.2 2.2e-19 69.4 0.1 1.3 1 0 0 1 1 1 1 VHS domain Serglycin PF04360.7 OAJ26693.1 - 6.1 6.5 9.8 0.7 9.6 3.2 2.0 2 0 0 2 2 2 0 Serglycin RINGv PF12906.2 OAJ26695.1 - 1.6e-06 28.0 7.1 5.3e-06 26.3 1.7 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 OAJ26695.1 - 0.0081 15.9 4.0 0.0081 15.9 2.8 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_4 PF14570.1 OAJ26695.1 - 0.32 10.6 1.8 0.75 9.4 1.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 OAJ26695.1 - 1.1 9.2 4.7 0.42 10.6 1.1 1.8 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 OAJ26695.1 - 2.1 8.4 5.2 12 5.9 2.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 OAJ26695.1 - 7.4 6.7 7.8 21 5.3 5.4 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger UCH PF00443.24 OAJ26696.1 - 3.8e-48 163.9 0.0 4.6e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ26696.1 - 1.1e-20 74.3 0.0 2.5e-20 73.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 OAJ26696.1 - 2.3e-08 33.2 0.0 5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 OAJ26696.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain Adaptin_N PF01602.15 OAJ26697.1 - 1.9e-146 488.4 7.5 2.4e-146 488.1 5.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 OAJ26697.1 - 1.7e-28 99.6 2.0 1.2e-24 87.0 0.1 3.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 OAJ26697.1 - 1.7e-18 66.6 4.5 1.3e-09 38.1 0.0 5.7 1 1 6 7 7 7 6 HEAT repeats HEAT PF02985.17 OAJ26697.1 - 8.9e-12 44.0 4.1 0.00075 19.3 0.0 6.2 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 OAJ26697.1 - 2.7e-08 34.0 4.5 0.0009 19.6 0.0 7.0 6 3 3 9 9 9 1 HEAT-like repeat CLASP_N PF12348.3 OAJ26697.1 - 0.00022 20.6 0.4 1.2 8.4 0.0 4.0 2 2 2 4 4 4 2 CLASP N terminal Cnd3 PF12719.2 OAJ26697.1 - 0.0058 15.6 0.1 0.068 12.1 0.0 2.6 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain Aminoglyc_resit PF10706.4 OAJ26697.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase zf-H2C2_2 PF13465.1 OAJ26698.1 - 2.8e-07 30.4 11.2 2.3e-06 27.6 1.4 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 OAJ26698.1 - 4.5e-07 29.7 12.0 0.01 16.1 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 OAJ26698.1 - 3.5e-06 27.0 11.8 0.031 14.6 0.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 OAJ26698.1 - 0.025 14.7 2.6 0.025 14.7 1.8 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PAF-AH_p_II PF03403.8 OAJ26700.1 - 1e-37 129.3 0.0 7e-20 70.6 0.2 3.0 2 2 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 OAJ26700.1 - 4.9e-10 39.3 0.3 1.1e-08 34.9 0.2 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ26700.1 - 0.026 14.3 0.2 0.056 13.3 0.1 1.5 1 0 0 1 1 1 0 Putative lysophospholipase 4HBT_3 PF13622.1 OAJ26701.1 - 1.2e-31 110.3 1.5 1.7e-31 109.9 1.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 OAJ26701.1 - 4.8e-06 26.2 0.0 9.5e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA thioesterase zf-CCHC_2 PF13696.1 OAJ26702.1 - 0.094 12.2 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 OAJ26702.1 - 1.3 9.1 3.6 2.3 8.3 2.5 1.4 1 0 0 1 1 1 0 Zinc knuckle HSP70 PF00012.15 OAJ26703.1 - 8.1e-262 869.5 11.4 9.4e-262 869.2 7.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAJ26703.1 - 1.4e-15 56.7 2.1 3.6e-13 48.8 0.5 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 OAJ26703.1 - 1.4e-05 24.9 2.0 0.2 11.4 0.2 3.4 2 1 0 2 2 2 2 Cell division protein FtsA Hydantoinase_A PF01968.13 OAJ26703.1 - 0.0034 16.5 8.5 0.46 9.5 0.4 3.3 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Seryl_tRNA_N PF02403.17 OAJ26703.1 - 0.013 15.5 8.6 0.045 13.7 5.8 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CAF-1_p150 PF11600.3 OAJ26704.1 - 0.12 11.7 0.1 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BTK PF00779.14 OAJ26704.1 - 0.25 10.9 1.2 0.5 10.0 0.9 1.5 1 0 0 1 1 1 0 BTK motif RVT_2 PF07727.9 OAJ26705.1 - 3.9e-84 281.4 0.0 5.3e-84 281.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ26705.1 - 4e-20 72.1 0.0 2.2e-19 69.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ26705.1 - 6.3e-07 28.9 0.0 1.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain Trypan_PARP PF05887.6 OAJ26707.1 - 0.042 13.6 3.0 0.1 12.4 2.1 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Cupin_1 PF00190.17 OAJ26708.1 - 3.3e-29 101.1 0.0 4.2e-15 55.4 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 OAJ26708.1 - 3.1e-26 90.6 0.5 7.6e-14 50.9 0.0 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 OAJ26708.1 - 3.7e-10 39.6 0.4 2.5e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 OAJ26708.1 - 1.9e-07 30.3 0.0 0.013 14.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 OAJ26708.1 - 0.00085 18.9 0.3 0.012 15.2 0.1 2.4 1 1 0 2 2 2 1 Cupin MannoseP_isomer PF01050.13 OAJ26708.1 - 0.00087 18.9 0.0 0.45 10.1 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase Cupin_7 PF12973.2 OAJ26708.1 - 0.0093 15.7 0.2 0.95 9.3 0.0 2.7 2 1 0 2 2 2 1 ChrR Cupin-like domain ARD PF03079.9 OAJ26708.1 - 0.015 15.2 0.0 0.33 10.8 0.0 2.4 2 0 0 2 2 2 0 ARD/ARD' family 3-HAO PF06052.7 OAJ26708.1 - 0.016 14.6 0.0 3.9 6.8 0.0 2.4 2 1 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase GPI PF06560.6 OAJ26708.1 - 0.1 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Sugar_tr PF00083.19 OAJ26709.1 - 7.2e-118 394.0 20.0 8.8e-117 390.4 13.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ26709.1 - 2.7e-20 72.4 63.6 4.8e-19 68.2 25.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily YqhR PF11085.3 OAJ26709.1 - 0.00041 19.9 1.3 0.097 12.2 0.3 2.7 2 0 0 2 2 2 2 Conserved membrane protein YqhR DUF1229 PF06797.6 OAJ26709.1 - 0.045 12.6 4.7 4.6 5.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1229) DUF441 PF04284.8 OAJ26709.1 - 1.5 8.6 8.6 0.54 10.1 3.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF441) DUF1049 PF06305.6 OAJ26709.1 - 6.8 6.2 8.3 8.7 5.8 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DnaJ PF00226.26 OAJ26715.1 - 3.5e-16 58.6 0.1 7.2e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Rav1p_C PF12234.3 OAJ26716.1 - 9e-88 295.0 0.0 1.2e-87 294.5 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal Oxidored_FMN PF00724.15 OAJ26717.1 - 8e-60 202.6 0.0 1e-59 202.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 OAJ26717.1 - 0.039 12.8 0.0 0.099 11.4 0.0 1.6 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) ADH_N PF08240.7 OAJ26718.1 - 1.1e-20 73.4 2.4 2e-20 72.5 1.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ26718.1 - 4.2e-16 58.6 0.0 7.1e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 OAJ26718.1 - 2.3e-05 24.5 0.0 0.002 18.1 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 OAJ26718.1 - 0.00011 21.4 0.1 0.0002 20.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.1 OAJ26718.1 - 0.0069 16.6 0.0 0.047 13.9 0.0 2.1 2 0 0 2 2 2 1 XdhC Rossmann domain 3HCDH_N PF02737.13 OAJ26718.1 - 0.0079 15.8 0.1 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 OAJ26718.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 OAJ26718.1 - 0.023 14.5 2.0 0.051 13.4 1.4 1.5 1 0 0 1 1 1 0 ThiF family GFO_IDH_MocA PF01408.17 OAJ26718.1 - 0.047 14.2 0.0 0.096 13.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold adh_short PF00106.20 OAJ26719.1 - 4.4e-18 65.7 0.5 9.6e-13 48.3 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 OAJ26719.1 - 2e-06 27.6 2.3 1.5e-05 24.7 1.5 2.4 1 1 0 1 1 1 1 KR domain TFIIB PF00382.14 OAJ26720.1 - 3.9e-39 132.3 3.1 2.7e-22 78.3 0.7 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 OAJ26720.1 - 1.6e-12 46.5 1.6 2.8e-12 45.7 1.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 OAJ26720.1 - 0.004 17.0 0.0 3.5 7.5 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain Cyclin_N PF00134.18 OAJ26720.1 - 0.07 12.7 0.7 0.24 10.9 0.1 1.9 2 0 0 2 2 2 0 Cyclin, N-terminal domain ThiF PF00899.16 OAJ26721.1 - 7.4e-33 113.2 0.0 1.2e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 OAJ26721.1 - 0.0069 16.4 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoCF_biosynth PF00994.19 OAJ26722.1 - 8.1e-52 174.4 0.7 8.6e-28 96.5 0.0 2.8 3 0 0 3 3 3 2 Probable molybdopterin binding domain MoeA_N PF03453.12 OAJ26722.1 - 1.1e-28 99.5 1.6 2.2e-28 98.6 1.1 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 OAJ26722.1 - 1e-14 54.1 0.1 2.8e-14 52.8 0.1 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) PyrBI_leader PF08052.6 OAJ26722.1 - 0.09 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 PyrBI operon leader peptide Pro_CA PF00484.14 OAJ26723.1 - 7.8e-29 100.6 0.1 9.3e-29 100.3 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase SNARE PF05739.14 OAJ26724.1 - 7.6e-17 60.7 5.5 1.1e-16 60.2 2.9 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 OAJ26724.1 - 5.6e-11 42.5 4.1 7.3e-10 38.9 0.1 2.3 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 OAJ26724.1 - 0.0014 18.1 6.5 0.0027 17.3 1.3 2.2 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3708 PF12501.3 OAJ26724.1 - 0.66 9.8 6.7 7.6 6.3 0.1 2.4 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter SlyX PF04102.7 OAJ26724.1 - 1.2 9.5 6.6 8.6 6.8 0.5 3.3 2 1 1 3 3 3 0 SlyX Diphthamide_syn PF01866.12 OAJ26725.1 - 4e-47 160.9 0.0 3.3e-23 82.3 0.0 4.2 3 1 0 3 3 3 3 Putative diphthamide synthesis protein RabGAP-TBC PF00566.13 OAJ26726.1 - 5.6e-28 97.8 0.0 1.4e-27 96.5 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Rotamase PF00639.16 OAJ26727.1 - 2.6e-19 69.7 0.0 4.9e-19 68.8 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 OAJ26727.1 - 1.3e-16 60.9 0.0 1.7e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 OAJ26727.1 - 4.1e-07 29.7 0.9 4.1e-07 29.7 0.6 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 OAJ26727.1 - 0.024 15.2 0.0 0.056 14.0 0.0 1.6 2 0 0 2 2 2 0 PPIC-type PPIASE domain Yae1_N PF09811.4 OAJ26728.1 - 6.6e-13 47.9 0.4 6.6e-13 47.9 0.2 2.0 2 0 0 2 2 2 1 Essential protein Yae1, N terminal zf-UBR PF02207.15 OAJ26729.1 - 7.3e-14 51.2 14.7 7.3e-14 51.2 10.2 3.0 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 OAJ26729.1 - 4.8e-09 35.8 0.1 1.6e-08 34.1 0.1 2.0 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.4 OAJ26729.1 - 0.013 14.7 0.3 0.032 13.4 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL WD40 PF00400.27 OAJ26730.1 - 5.7e-10 38.6 0.0 0.37 10.7 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat CPSF100_C PF13299.1 OAJ26730.1 - 0.049 13.8 0.8 0.11 12.7 0.6 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Nucleoporin_N PF08801.6 OAJ26730.1 - 0.095 11.4 0.0 0.39 9.4 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like Nop14 PF04147.7 OAJ26730.1 - 0.16 9.8 15.2 0.23 9.3 10.5 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 OAJ26730.1 - 0.54 9.4 15.3 0.77 8.9 10.6 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 OAJ26730.1 - 8 4.3 10.3 11 3.8 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Pex2_Pex12 PF04757.9 OAJ26731.1 - 3.9e-35 121.3 0.7 1.8e-23 83.1 0.0 2.1 2 0 0 2 2 2 2 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 OAJ26731.1 - 0.031 14.2 0.8 0.056 13.4 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ26731.1 - 0.065 12.9 0.4 0.11 12.1 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RhoGEF PF00621.15 OAJ26732.1 - 1.6e-38 132.3 0.0 2.5e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.2 OAJ26732.1 - 3.5e-11 42.4 0.2 2e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ26732.1 - 2.3e-09 36.8 0.2 0.0001 22.0 0.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 OAJ26732.1 - 1.2e-06 27.7 0.1 1.6 9.0 0.0 4.7 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 OAJ26732.1 - 0.0012 18.6 0.4 34 5.2 0.0 4.2 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 OAJ26732.1 - 0.16 12.1 1.1 5.8 7.3 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeat SSV1_ORF_D-335 PF07935.6 OAJ26732.1 - 0.8 9.4 0.3 14 5.4 0.0 2.4 2 0 0 2 2 2 0 ORF D-335-like protein GTP_EFTU PF00009.22 OAJ26733.1 - 5.3e-17 61.8 0.0 7.1e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Peroxidase_2 PF01328.12 OAJ26735.1 - 2.7e-08 32.8 0.1 5.1e-08 31.9 0.1 1.4 1 1 0 1 1 1 1 Peroxidase, family 2 Ank PF00023.25 OAJ26737.1 - 0.00022 20.8 0.4 0.0012 18.5 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 OAJ26737.1 - 0.00022 21.1 0.0 0.00056 19.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 OAJ26737.1 - 0.0011 19.1 0.1 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 OAJ26737.1 - 0.0012 19.1 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ26737.1 - 0.002 18.5 0.0 0.0032 17.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF2076 PF09849.4 OAJ26737.1 - 1.4 8.8 7.6 1.8 8.5 5.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF3439 PF11921.3 OAJ26739.1 - 0.0031 17.2 1.7 0.0056 16.4 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) DUF4367 PF14285.1 OAJ26739.1 - 0.014 14.7 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) Dicty_REP PF05086.7 OAJ26739.1 - 0.093 10.4 0.3 0.11 10.2 0.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDK2AP PF09806.4 OAJ26739.1 - 1 9.5 8.5 1.9 8.7 5.9 1.6 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein AAA_33 PF13671.1 OAJ26741.1 - 5.7e-20 71.6 1.2 4.4e-19 68.7 0.9 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAJ26741.1 - 9.8e-09 34.5 0.0 0.00055 19.0 0.0 2.3 1 1 1 2 2 2 2 Zeta toxin tRNA_lig_kinase PF08303.6 OAJ26741.1 - 4.7e-08 33.0 0.1 7e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 tRNA ligase kinase domain KTI12 PF08433.5 OAJ26741.1 - 5.5e-08 32.3 1.7 1.6e-06 27.5 0.1 2.1 1 1 1 2 2 2 1 Chromatin associated protein KTI12 CPT PF07931.7 OAJ26741.1 - 0.00074 19.1 0.1 0.11 12.1 0.0 2.2 1 1 1 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.1 OAJ26741.1 - 0.0008 19.5 0.0 0.0021 18.2 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 OAJ26741.1 - 0.0012 19.1 2.0 0.11 12.8 1.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ26741.1 - 0.02 15.7 0.0 0.037 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 OAJ26741.1 - 0.033 14.1 0.0 0.056 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 OAJ26741.1 - 0.034 12.8 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_19 PF13245.1 OAJ26741.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.9 1 1 0 1 1 1 0 Part of AAA domain APS_kinase PF01583.15 OAJ26741.1 - 0.051 13.2 0.3 0.22 11.1 0.0 1.9 1 1 1 2 2 2 0 Adenylylsulphate kinase SKI PF01202.17 OAJ26741.1 - 0.065 13.1 0.4 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase Thymidylate_kin PF02223.12 OAJ26741.1 - 0.11 11.8 0.0 4.1 6.7 0.1 2.5 2 1 0 2 2 2 0 Thymidylate kinase C1-set PF07654.10 OAJ26741.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin C1-set domain PP-binding PF00550.20 OAJ26742.1 - 1e-15 57.7 0.4 1.5e-15 57.1 0.3 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 OAJ26742.1 - 4.1e-07 29.9 0.2 6.6e-07 29.2 0.2 1.4 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 OAJ26742.1 - 0.073 13.1 0.1 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ribosomal_L17 PF01196.14 OAJ26743.1 - 3.2e-26 91.7 0.0 8.9e-26 90.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L17 Ribosomal_L11_N PF03946.9 OAJ26744.1 - 5.9e-25 86.4 0.7 9.7e-25 85.8 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 OAJ26744.1 - 6.8e-22 77.3 0.3 1.1e-21 76.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Clat_adaptor_s PF01217.15 OAJ26745.1 - 1.5e-19 70.1 0.0 2.4e-16 59.7 0.0 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain K_channel_TID PF07941.6 OAJ26745.1 - 0.69 10.1 2.9 8.7 6.6 0.3 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain NB-ARC PF00931.17 OAJ26746.1 - 5.4e-05 22.2 0.0 8.4e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 OAJ26746.1 - 0.00096 19.0 0.3 0.0041 16.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 OAJ26746.1 - 0.0053 15.5 0.0 0.0077 15.0 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 OAJ26746.1 - 0.012 16.4 0.1 0.043 14.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 OAJ26746.1 - 0.02 14.4 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 OAJ26746.1 - 0.026 13.4 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.5 OAJ26746.1 - 0.09 11.9 0.0 0.2 10.8 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 OAJ26746.1 - 0.099 12.9 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 OAJ26746.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.24 OAJ26746.1 - 0.16 12.1 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) COesterase PF00135.23 OAJ26747.1 - 6.1e-77 259.5 0.3 2.2e-68 231.2 0.3 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ26747.1 - 0.00083 18.9 0.1 0.0062 16.1 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold KH_1 PF00013.24 OAJ26748.1 - 2.4e-05 23.8 0.0 4.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 OAJ26748.1 - 4.7e-05 22.9 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 OAJ26748.1 - 0.049 13.2 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 KH domain DUF2332 PF10094.4 OAJ26749.1 - 0.063 12.2 0.1 0.09 11.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) Nup84_Nup100 PF04121.8 OAJ26750.1 - 5.3e-80 269.0 0.0 3.4e-38 130.8 0.0 4.4 4 0 0 4 4 4 4 Nuclear pore protein 84 / 107 ThiF PF00899.16 OAJ26751.1 - 1.3e-09 38.0 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family Histone PF00125.19 OAJ26752.1 - 8.6e-14 51.4 0.1 1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ26752.1 - 0.00012 22.2 0.0 0.00016 21.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 OAJ26752.1 - 0.00024 20.9 0.1 0.00034 20.4 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 OAJ26752.1 - 0.00077 19.4 0.1 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 OAJ26752.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T HA2 PF04408.18 OAJ26753.1 - 1.9e-24 85.5 0.0 6.4e-24 83.9 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 OAJ26753.1 - 4.1e-23 81.3 0.0 1.3e-22 79.7 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 OAJ26753.1 - 6.4e-13 48.3 0.0 1.5e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ26753.1 - 9e-09 35.0 0.1 2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ26753.1 - 3.6e-06 27.1 0.1 9.5e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 OAJ26753.1 - 0.001 18.0 0.0 0.0023 16.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 OAJ26753.1 - 0.0049 16.9 0.1 0.031 14.3 0.0 2.3 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 OAJ26753.1 - 0.011 15.5 0.1 0.083 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 OAJ26753.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 KaiC SRP54 PF00448.17 OAJ26753.1 - 0.014 14.8 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ResIII PF04851.10 OAJ26753.1 - 0.022 14.5 0.0 8.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.7 OAJ26753.1 - 0.082 12.5 0.4 0.85 9.2 0.0 2.4 3 0 0 3 3 3 0 NACHT domain Arch_ATPase PF01637.13 OAJ26753.1 - 0.086 12.5 0.1 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Myosin_head PF00063.16 OAJ26753.1 - 0.11 10.5 0.0 0.17 9.9 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) Metallophos PF00149.23 OAJ26755.1 - 1.7e-12 47.1 0.8 6.2e-12 45.3 0.5 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAJ26755.1 - 0.00015 21.6 0.0 0.00092 19.0 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Far-17a_AIG1 PF04750.9 OAJ26756.1 - 5.6e-42 143.1 6.3 6.8e-42 142.9 4.4 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Inositol_P PF00459.20 OAJ26757.1 - 9.5e-53 179.2 0.5 6.6e-52 176.4 0.4 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family ERCC4 PF02732.10 OAJ26758.1 - 5.4e-26 91.0 0.0 1.4e-25 89.7 0.0 1.7 2 0 0 2 2 2 1 ERCC4 domain HHH_8 PF14716.1 OAJ26758.1 - 0.0025 17.9 0.0 0.0064 16.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Exo5 PF09810.4 OAJ26760.1 - 2.2e-51 175.0 0.1 5e-45 154.1 0.1 3.3 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease MUG113 PF13455.1 OAJ26761.1 - 1.2e-16 60.8 0.2 3.4e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 OAJ26761.1 - 2.6e-09 37.3 0.0 1.8e-08 34.6 0.0 2.3 1 1 0 1 1 1 1 T5orf172 domain Aminotran_5 PF00266.14 OAJ26762.1 - 9e-32 110.2 0.2 2e-27 95.8 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 OAJ26762.1 - 1.5e-06 26.8 0.0 4.2e-06 25.3 0.0 1.9 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme HTH_9 PF08221.6 OAJ26762.1 - 0.074 12.9 0.1 3.8 7.4 0.0 2.8 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain PNK3P PF08645.6 OAJ26763.1 - 1.4e-37 128.6 0.2 8.2e-21 74.0 0.0 2.4 2 0 0 2 2 2 2 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 OAJ26763.1 - 1.4e-25 89.8 0.0 1.7e-24 86.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAJ26763.1 - 3e-05 23.2 0.0 0.079 12.0 0.0 2.3 1 1 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 OAJ26763.1 - 0.015 16.1 0.0 0.42 11.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.5 OAJ26763.1 - 0.02 14.1 0.0 0.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_22 PF13401.1 OAJ26763.1 - 0.038 14.1 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Methyltransf_23 PF13489.1 OAJ26768.1 - 7e-18 64.8 1.5 1.8e-17 63.5 1.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ26768.1 - 5.5e-16 58.8 0.1 8.8e-15 54.9 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ26768.1 - 1.5e-15 57.0 0.0 7.2e-13 48.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ26768.1 - 8.9e-15 55.2 0.0 2.2e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ26768.1 - 2.7e-13 50.2 1.8 2.1e-12 47.3 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ26768.1 - 3.1e-09 37.0 0.1 3.1e-09 37.0 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ26768.1 - 4.5e-08 33.1 0.5 1.4e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ26768.1 - 2.6e-06 26.7 0.1 0.014 14.4 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family MTS PF05175.9 OAJ26768.1 - 0.00039 19.8 5.8 0.0024 17.2 0.1 3.3 1 1 2 3 3 3 1 Methyltransferase small domain NodS PF05401.6 OAJ26768.1 - 0.00046 19.6 0.0 0.01 15.2 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) RrnaAD PF00398.15 OAJ26768.1 - 0.00049 19.2 0.0 0.0012 17.9 0.0 1.6 1 1 1 2 2 2 1 Ribosomal RNA adenine dimethylase Zip PF02535.17 OAJ26768.1 - 0.0028 16.7 17.7 0.0038 16.2 12.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DREV PF05219.7 OAJ26768.1 - 0.0045 15.8 0.0 0.013 14.3 0.0 1.6 2 0 0 2 2 2 1 DREV methyltransferase TehB PF03848.9 OAJ26768.1 - 0.005 16.0 0.0 0.11 11.6 0.0 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TehB PCMT PF01135.14 OAJ26768.1 - 0.01 15.3 0.0 0.16 11.5 0.0 2.1 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 OAJ26768.1 - 0.031 12.9 0.0 0.58 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) TPMT PF05724.6 OAJ26768.1 - 0.061 12.7 0.0 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) AlaDh_PNT_C PF01262.16 OAJ26768.1 - 0.072 12.6 0.1 0.16 11.5 0.0 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pox_MCEL PF03291.11 OAJ26768.1 - 0.094 11.5 0.0 0.17 10.7 0.0 1.4 1 1 0 1 1 1 0 mRNA capping enzyme V-SNARE_C PF12352.3 OAJ26769.1 - 9.2e-18 64.0 7.6 2e-17 63.0 4.9 1.9 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 OAJ26769.1 - 1.8e-15 56.8 12.1 2.8e-15 56.2 2.3 3.1 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Prominin PF05478.6 OAJ26769.1 - 0.0051 14.4 1.4 0.027 12.0 0.0 2.1 2 1 0 2 2 2 1 Prominin Fusion_gly PF00523.13 OAJ26769.1 - 0.0066 14.5 0.2 0.0066 14.5 0.1 1.5 2 0 0 2 2 2 1 Fusion glycoprotein F0 PNK3P PF08645.6 OAJ26769.1 - 0.013 14.8 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Sec20 PF03908.8 OAJ26769.1 - 0.059 13.0 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 Sec20 YqjK PF13997.1 OAJ26769.1 - 0.075 13.2 0.6 0.075 13.2 0.4 2.1 2 0 0 2 2 2 0 YqjK-like protein DUF912 PF06024.7 OAJ26769.1 - 0.11 12.5 1.1 0.74 9.8 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2939 PF11159.3 OAJ26769.1 - 0.13 12.4 0.8 0.27 11.4 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) ApoLp-III PF07464.6 OAJ26769.1 - 0.18 11.8 10.1 1.5 8.8 0.2 2.8 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Fib_alpha PF08702.5 OAJ26769.1 - 0.28 11.2 5.7 0.8 9.8 1.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Sec8_exocyst PF04048.9 OAJ26769.1 - 0.33 10.5 3.7 0.67 9.5 0.1 2.5 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Sigma_reg_N PF13800.1 OAJ26769.1 - 0.45 10.5 3.6 0.86 9.6 2.5 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal ODV-E18 PF10717.4 OAJ26769.1 - 1.9 7.9 4.6 0.81 9.1 0.3 2.2 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Gryzun PF07919.7 OAJ26770.1 - 2.9e-29 101.8 0.0 7e-28 97.2 0.0 2.6 2 1 0 2 2 2 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 OAJ26770.1 - 0.001 18.6 0.0 0.0027 17.2 0.0 1.7 1 1 0 1 1 1 1 Foie gras liver health family 1 CoA_transf_3 PF02515.12 OAJ26771.1 - 4.2e-46 156.6 0.0 6.5e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III Foie-gras_1 PF11817.3 OAJ26773.1 - 0.0011 18.4 0.0 0.0032 16.9 0.0 1.8 1 1 0 1 1 1 1 Foie gras liver health family 1 Carn_acyltransf PF00755.15 OAJ26774.1 - 1.3e-155 518.9 0.0 1.8e-155 518.4 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rho_GDI PF02115.12 OAJ26775.1 - 1.6e-49 168.0 0.0 1.9e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Cpn60_TCP1 PF00118.19 OAJ26776.1 - 1.9e-135 452.2 1.0 2.2e-135 452.0 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.6 OAJ26776.1 - 0.049 13.0 0.4 0.36 10.2 0.1 2.5 3 0 0 3 3 3 0 Propionate catabolism activator LRR_9 PF14580.1 OAJ26777.1 - 2.4e-57 193.3 0.0 3.2e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 OAJ26777.1 - 2.2e-14 52.6 1.4 7.6e-07 28.6 0.1 3.0 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ26777.1 - 3.2e-10 39.5 0.4 7.5e-09 35.2 0.2 2.8 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 OAJ26777.1 - 0.0013 18.5 2.3 12 6.3 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.28 OAJ26777.1 - 0.006 16.4 2.5 12 6.4 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 OAJ26777.1 - 0.052 13.7 3.4 56 4.6 0.0 4.5 4 0 0 4 4 4 0 Leucine rich repeat Mnd1 PF03962.10 OAJ26778.1 - 0.0082 15.8 10.0 0.0082 15.8 6.9 6.8 1 1 4 6 6 6 2 Mnd1 family DUF4239 PF14023.1 OAJ26778.1 - 0.56 9.5 27.3 0.68 9.2 1.7 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4239) Glucan_synthase PF02364.10 OAJ26779.1 - 0 1365.9 0.0 0 1365.5 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 OAJ26779.1 - 2e-37 127.6 0.0 4.6e-37 126.4 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 RhoGAP PF00620.22 OAJ26780.1 - 8.8e-37 126.0 0.0 1.9e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain STT3 PF02516.9 OAJ26781.1 - 9.4e-135 450.2 34.2 8.6e-133 443.8 23.7 2.1 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit DUF1978 PF09321.5 OAJ26781.1 - 0.18 11.2 0.1 0.27 10.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) PseudoU_synth_2 PF00849.17 OAJ26782.1 - 9.3e-27 93.8 0.1 1.4e-26 93.2 0.1 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Y_phosphatase2 PF03162.8 OAJ26783.1 - 2.7e-50 169.9 0.0 3e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 OAJ26783.1 - 4.9e-05 23.6 0.0 0.0011 19.2 0.0 2.0 1 1 1 2 2 2 1 Tyrosine phosphatase family HTH_CodY PF08222.6 OAJ26783.1 - 0.13 11.6 0.0 0.55 9.6 0.0 2.0 2 1 0 2 2 2 0 CodY helix-turn-helix domain MIF4G PF02854.14 OAJ26784.1 - 1.3e-54 184.8 0.8 2.2e-54 184.0 0.5 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 OAJ26784.1 - 4.8e-12 45.5 0.0 2e-11 43.6 0.0 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 THRAP3_BCLAF1 PF15440.1 OAJ26784.1 - 0.00025 19.8 36.7 0.00025 19.8 25.4 4.3 4 0 0 4 4 4 1 THRAP3/BCLAF1 family MIP-T3 PF10243.4 OAJ26784.1 - 0.00048 18.7 61.2 0.00048 18.7 42.4 4.4 4 1 0 4 4 4 1 Microtubule-binding protein MIP-T3 DUF1408 PF07193.6 OAJ26785.1 - 0.44 10.1 5.7 0.2 11.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1408) PPTA PF01239.17 OAJ26786.1 - 4e-43 143.0 18.0 5.5e-09 34.9 0.1 5.8 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Alg6_Alg8 PF03155.10 OAJ26788.1 - 2.9e-108 362.7 13.9 2.5e-48 165.0 0.0 3.0 3 0 0 3 3 3 3 ALG6, ALG8 glycosyltransferase family ALG3 PF05208.8 OAJ26788.1 - 0.82 8.8 5.6 4.2 6.5 0.7 2.5 1 1 1 2 2 2 0 ALG3 protein DEAD PF00270.24 OAJ26790.1 - 5.7e-39 133.3 0.0 1.2e-38 132.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ26790.1 - 2.6e-21 75.2 0.0 6.3e-21 74.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 OAJ26790.1 - 6.2e-18 64.3 2.3 6.2e-18 64.3 1.6 2.8 3 0 0 3 3 3 1 DBP10CT (NUC160) domain ResIII PF04851.10 OAJ26790.1 - 0.0035 17.1 0.0 0.089 12.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit GHMP_kinases_C PF08544.8 OAJ26791.1 - 2.1e-11 43.8 0.0 4.6e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Ldh_1_N PF00056.18 OAJ26791.1 - 0.0046 16.7 0.1 0.0082 15.9 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain GalKase_gal_bdg PF10509.4 OAJ26792.1 - 1.2e-20 72.4 0.0 2.2e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 OAJ26792.1 - 3.4e-12 46.2 1.2 3.4e-12 46.2 0.8 2.7 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 OAJ26792.1 - 1e-10 41.6 0.0 2.4e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal DUF4142 PF13628.1 OAJ26792.1 - 0.11 12.5 0.1 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) Aconitase PF00330.15 OAJ26793.1 - 3.6e-150 500.4 0.0 7.2e-150 499.5 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAJ26793.1 - 6.5e-32 110.3 0.0 1.4e-31 109.2 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain MRP-L28 PF09812.4 OAJ26793.1 - 0.00079 19.2 0.3 0.0036 17.1 0.2 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L28 Ribosomal_L37e PF01907.14 OAJ26794.1 - 2.1e-24 85.0 13.7 3.5e-24 84.3 9.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 OAJ26794.1 - 0.0018 18.0 1.8 0.0028 17.4 1.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon LIM PF00412.17 OAJ26794.1 - 0.046 13.7 2.3 0.07 13.2 1.6 1.3 1 0 0 1 1 1 0 LIM domain SelR PF01641.13 OAJ26794.1 - 0.049 13.3 0.1 0.049 13.3 0.1 1.2 1 0 0 1 1 1 0 SelR domain Radical_SAM PF04055.16 OAJ26794.1 - 0.052 13.7 0.5 0.059 13.5 0.3 1.1 1 0 0 1 1 1 0 Radical SAM superfamily HypA PF01155.14 OAJ26794.1 - 0.095 12.3 1.0 0.14 11.8 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 OAJ26794.1 - 1.2 8.4 3.5 3.3 7.0 2.4 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zf-C2H2_3 PF13878.1 OAJ26794.1 - 1.4 8.5 5.2 5.4 6.6 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-C3HC4 PF00097.20 OAJ26794.1 - 4.7 6.9 7.6 7.6 6.2 5.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S14 PF00253.16 OAJ26794.1 - 8.8 5.7 11.6 0.53 9.7 0.5 2.7 1 1 2 3 3 3 0 Ribosomal protein S14p/S29e Ribosomal_L7Ae PF01248.21 OAJ26795.1 - 3.7e-23 80.8 0.0 4.3e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family EnY2 PF10163.4 OAJ26796.1 - 4.1e-11 42.6 0.0 6.9e-11 41.9 0.0 1.4 2 0 0 2 2 2 1 Transcription factor e(y)2 Ten1 PF12658.2 OAJ26796.1 - 0.014 15.1 0.0 0.018 14.7 0.0 1.3 1 1 0 1 1 1 0 Telomere capping, CST complex subunit Mit_KHE1 PF10173.4 OAJ26796.1 - 0.035 13.9 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Prp18 PF02840.10 OAJ26796.1 - 0.055 13.2 0.7 0.19 11.5 0.5 1.7 1 1 1 2 2 2 0 Prp18 domain NRDE-2 PF08424.5 OAJ26796.1 - 0.056 12.3 2.7 0.061 12.1 1.9 1.1 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference DUF2309 PF10070.4 OAJ26796.1 - 0.12 10.4 0.5 0.14 10.2 0.3 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) PRP1_N PF06424.7 OAJ26796.1 - 0.14 12.4 1.2 0.21 11.9 0.9 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal CK_II_beta PF01214.13 OAJ26796.1 - 0.15 11.5 0.4 0.2 11.1 0.3 1.2 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Med15 PF09606.5 OAJ26796.1 - 0.81 7.8 8.3 0.81 7.8 5.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TSA PF03249.8 OAJ26796.1 - 1.7 7.0 9.5 2 6.8 6.6 1.0 1 0 0 1 1 1 0 Type specific antigen DASH_Duo1 PF08651.5 OAJ26797.1 - 9.6e-18 63.5 0.0 1.4e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 Med2 PF11214.3 OAJ26797.1 - 4.1 7.4 6.6 15 5.7 4.5 1.9 1 1 0 1 1 1 0 Mediator complex subunit 2 rve PF00665.21 OAJ26798.1 - 1.3e-25 89.8 0.0 2.5e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain UBN2 PF14223.1 OAJ26798.1 - 7.9e-08 32.1 0.1 1.6e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 OAJ26798.1 - 5.3e-07 29.6 0.1 1.7e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein gag_pre-integrs PF13976.1 OAJ26798.1 - 1.8e-05 24.2 0.0 6.8e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain UBN2_2 PF14227.1 OAJ26798.1 - 0.00036 20.0 0.0 0.00063 19.2 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Fer2_BFD PF04324.10 OAJ26798.1 - 0.0034 17.4 0.1 0.0095 15.9 0.1 1.7 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain rve_3 PF13683.1 OAJ26798.1 - 0.012 15.1 0.1 0.085 12.4 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain HTH_Tnp_ISL3 PF13542.1 OAJ26799.1 - 0.038 13.1 0.1 0.075 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF2537 PF10801.3 OAJ26799.1 - 0.067 13.2 1.5 0.18 11.9 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2537) AfsA PF03756.8 OAJ26799.1 - 0.068 12.8 0.2 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 A-factor biosynthesis hotdog domain FAM70 PF14967.1 OAJ26799.1 - 0.32 10.1 3.6 0.26 10.4 1.6 1.5 1 1 0 1 1 1 0 FAM70 protein Cyt-b5 PF00173.23 OAJ26800.1 - 4.1e-11 42.5 0.0 5.5e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.27 OAJ26801.1 - 0.0017 18.1 2.8 0.14 12.1 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Aldedh PF00171.17 OAJ26802.1 - 9.4e-125 416.5 0.1 1.2e-124 416.1 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAJ26802.1 - 0.093 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) WD40 PF00400.27 OAJ26803.1 - 8.8e-74 240.9 31.7 1.1e-08 34.5 0.4 12.0 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp13 PF08625.6 OAJ26803.1 - 4.5e-29 100.8 0.0 3.5e-18 65.6 0.0 2.3 2 0 0 2 2 2 2 Utp13 specific WD40 associated domain Nup160 PF11715.3 OAJ26803.1 - 8.4e-08 30.8 10.1 0.31 9.1 0.4 5.8 3 2 2 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAJ26803.1 - 2.3e-05 23.3 1.1 0.06 12.0 0.0 4.4 4 2 1 5 5 5 2 Nup133 N terminal like HSP70 PF00012.15 OAJ26804.1 - 4.8e-237 787.6 7.4 5.9e-237 787.4 5.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAJ26804.1 - 1.2e-18 66.8 0.8 8e-18 64.1 0.5 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 OAJ26804.1 - 0.0013 17.6 1.0 0.0096 14.7 0.2 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 OAJ26804.1 - 0.0014 18.3 0.1 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 OAJ26804.1 - 0.024 13.6 0.0 0.051 12.5 0.0 1.6 1 0 0 1 1 1 0 StbA protein Hydantoinase_A PF01968.13 OAJ26804.1 - 0.053 12.6 1.6 0.12 11.4 0.1 2.3 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase QRPTase_N PF02749.11 OAJ26804.1 - 0.091 12.5 0.1 16 5.4 0.0 3.1 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain Adaptin_N PF01602.15 OAJ26805.1 - 8.3e-99 331.2 0.0 5.9e-98 328.4 0.0 1.9 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 OAJ26805.1 - 0.0023 17.8 0.1 0.15 11.8 0.0 3.1 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 OAJ26805.1 - 0.0048 16.7 0.3 4.3 7.3 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF2435) Ipi1_N PF12333.3 OAJ26805.1 - 0.013 15.4 1.4 0.066 13.1 0.2 2.8 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.18 OAJ26805.1 - 0.025 14.4 1.9 14 5.7 0.0 5.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DLIC PF05783.6 OAJ26805.1 - 2.1 6.8 4.9 4 5.9 3.4 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Metallophos PF00149.23 OAJ26806.1 - 8.3e-40 136.3 0.3 1e-39 136.0 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAJ26806.1 - 0.0044 16.8 0.0 0.0055 16.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2268 PF10026.4 OAJ26806.1 - 0.057 12.7 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Ribosomal_S2 PF00318.15 OAJ26807.1 - 7.8e-41 139.6 0.0 1.4e-40 138.7 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S2 PH PF00169.24 OAJ26815.1 - 1.2e-07 31.8 0.1 2.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 OAJ26815.1 - 0.15 12.3 1.8 0.19 12.0 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain LSM PF01423.17 OAJ26816.1 - 1.3e-15 56.6 0.1 1.7e-15 56.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain Peptidase_M3 PF01432.15 OAJ26816.1 - 0.086 11.8 0.2 0.096 11.7 0.2 1.0 1 0 0 1 1 1 0 Peptidase family M3 DPBB_1 PF03330.13 OAJ26818.1 - 0.00044 20.2 0.6 0.00091 19.1 0.1 1.9 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel SRC-1 PF08832.5 OAJ26818.1 - 0.092 13.5 0.1 0.14 12.9 0.1 1.3 1 0 0 1 1 1 0 Steroid receptor coactivator Cerato-platanin PF07249.7 OAJ26818.1 - 0.1 12.6 0.1 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Cerato-platanin Rgp1 PF08737.5 OAJ26819.1 - 1.9e-71 241.3 0.0 5e-71 239.9 0.0 1.7 1 1 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 OAJ26819.1 - 0.00038 20.2 0.1 0.23 11.2 0.0 3.1 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain MCPVI PF02993.9 OAJ26819.1 - 0.28 11.3 4.7 0.94 9.5 3.3 1.9 1 0 0 1 1 1 0 Minor capsid protein VI Methyltransf_8 PF05148.10 OAJ26820.1 - 5.4e-52 176.5 0.0 6.8e-26 91.2 0.0 3.1 3 0 0 3 3 3 2 Hypothetical methyltransferase SLD3 PF08639.5 OAJ26820.1 - 0.0026 16.4 10.5 0.0042 15.7 7.3 1.3 1 1 0 1 1 1 1 DNA replication regulator SLD3 Methyltransf_11 PF08241.7 OAJ26820.1 - 0.0035 17.7 0.0 0.63 10.5 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ26820.1 - 0.0074 15.8 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 OAJ26820.1 - 0.012 15.0 0.2 1.7 7.9 0.1 2.4 2 0 0 2 2 2 0 Methyltransferase small domain eIF3_subunit PF08597.5 OAJ26820.1 - 0.33 10.4 10.8 0.17 11.3 4.2 2.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit GDI PF00996.13 OAJ26821.1 - 1.8e-49 168.2 0.0 2.9e-48 164.3 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor Rot1 PF10681.4 OAJ26822.1 - 1.9e-51 174.4 1.5 2.4e-51 174.1 1.1 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal DUF3140 PF11338.3 OAJ26823.1 - 1.2e-30 105.4 1.4 1.6e-30 105.0 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) Colicin-DNase PF12639.2 OAJ26823.1 - 0.085 13.1 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin DUF3673 PF12425.3 OAJ26823.1 - 0.096 12.5 0.1 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) DUF3907 PF13047.1 OAJ26823.1 - 0.12 12.0 0.1 0.44 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) TMA7 PF09072.5 OAJ26823.1 - 0.66 10.4 3.4 1.3 9.5 2.4 1.5 1 0 0 1 1 1 0 Translation machinery associated TMA7 DUF1640 PF07798.6 OAJ26824.1 - 8.6e-66 221.3 2.5 1e-65 221.0 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.13 OAJ26824.1 - 0.21 11.3 1.8 1.4 8.6 1.2 2.4 1 1 0 1 1 1 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 OAJ26824.1 - 0.67 9.8 3.2 8.1 6.4 0.5 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Zds_C PF08632.5 OAJ26825.1 - 4.3e-21 74.0 0.6 8e-21 73.1 0.4 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Glyco_hydro_cc PF11790.3 OAJ26826.1 - 2.9e-49 167.6 1.2 4.3e-49 167.1 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_16 PF00722.16 OAJ26827.1 - 1.8e-05 24.1 0.0 3.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Peptidase_M22 PF00814.20 OAJ26829.1 - 6.3e-66 222.6 0.1 8.2e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Adaptin_N PF01602.15 OAJ26830.1 - 1.2e-101 340.6 0.0 1.7e-101 340.1 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 OAJ26830.1 - 3e-53 179.7 0.0 6e-53 178.7 0.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 OAJ26830.1 - 1.7e-13 50.6 5.8 0.0012 19.0 0.1 5.7 2 2 5 7 7 7 4 HEAT repeats HEAT PF02985.17 OAJ26830.1 - 0.00089 19.1 8.6 0.77 10.0 0.1 6.4 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.2 OAJ26830.1 - 0.012 15.4 3.1 7.1 6.4 0.1 3.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.11 OAJ26830.1 - 0.021 15.2 3.4 23 5.8 0.0 5.2 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat WD40 PF00400.27 OAJ26831.1 - 1.4e-47 157.9 17.9 7.6e-11 41.4 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Rtf2 PF04641.7 OAJ26832.1 - 0.00029 20.1 0.1 0.00068 18.9 0.1 1.6 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 OAJ26832.1 - 0.0019 17.9 0.1 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAJ26832.1 - 0.0047 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ26832.1 - 0.023 14.4 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger CDC45 PF02724.9 OAJ26832.1 - 0.4 8.6 0.4 0.56 8.1 0.3 1.1 1 0 0 1 1 1 0 CDC45-like protein MRG PF05712.8 OAJ26833.1 - 1.6e-54 183.7 0.0 2.5e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 OAJ26833.1 - 3.2e-10 39.5 0.0 7.2e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Hep_59 PF07052.6 OAJ26833.1 - 0.02 15.2 1.5 2.4 8.5 0.0 2.7 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 PCI PF01399.22 OAJ26834.1 - 1.6e-05 25.1 0.0 3.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain K_channel_TID PF07941.6 OAJ26834.1 - 2 8.6 11.6 0.27 11.4 0.5 3.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain polyprenyl_synt PF00348.12 OAJ26835.1 - 1.6e-68 230.3 0.0 2.1e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase VMA21 PF09446.5 OAJ26836.1 - 2e-10 40.4 8.4 2.9e-10 39.9 5.8 1.3 1 0 0 1 1 1 1 VMA21-like domain Abhydrolase_3 PF07859.8 OAJ26837.1 - 2e-18 66.7 0.0 1.5e-17 63.8 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAJ26837.1 - 6.9e-10 38.1 0.0 6.3e-07 28.3 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF2424) SAPS PF04499.10 OAJ26837.1 - 1.1 7.7 13.2 2.3 6.7 9.2 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.11 OAJ26837.1 - 1.3 8.8 9.2 0.029 14.2 0.4 2.6 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 OAJ26837.1 - 2.3 5.7 16.8 4.5 4.8 11.6 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RVT_1 PF00078.22 OAJ26838.1 - 1e-11 44.6 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAJ26838.1 - 0.0002 21.7 0.0 0.00044 20.6 0.0 1.6 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAJ26838.1 - 0.025 14.3 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like Ank_2 PF12796.2 OAJ26840.1 - 3e-34 117.2 0.0 4.8e-14 52.4 0.0 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ26840.1 - 6.4e-32 109.3 1.3 2.8e-13 49.9 0.0 4.8 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 OAJ26840.1 - 6.6e-32 107.7 2.2 9.3e-11 40.9 0.0 5.7 5 1 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 OAJ26840.1 - 3e-28 97.1 1.0 3.5e-10 39.7 0.0 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ26840.1 - 2.5e-26 89.1 0.1 8.7e-08 31.6 0.0 5.8 5 1 1 6 6 6 4 Ankyrin repeat Cytochrom_C1 PF02167.10 OAJ26841.1 - 1.1e-86 289.9 0.0 1.5e-86 289.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 OAJ26841.1 - 0.00061 19.8 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 OAJ26841.1 - 0.033 14.9 0.2 0.15 12.9 0.1 2.3 2 1 0 2 2 2 0 Cytochrome c CAP_GLY PF01302.20 OAJ26842.1 - 2.5e-27 94.3 0.7 3.7e-27 93.8 0.5 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 OAJ26842.1 - 1.1e-11 44.7 0.0 3.5e-11 43.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain HMA PF00403.21 OAJ26844.1 - 7.6e-18 64.4 0.9 8.8e-18 64.2 0.6 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Alba PF01918.16 OAJ26844.1 - 0.05 13.1 0.1 0.085 12.4 0.0 1.6 2 0 0 2 2 2 0 Alba Gp37 PF09646.5 OAJ26844.1 - 0.097 12.1 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Gp37 protein CN_hydrolase PF00795.17 OAJ26847.1 - 5.9e-25 87.7 0.0 8.8e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_L24e PF01246.15 OAJ26848.1 - 6.2e-31 106.0 2.3 6.2e-31 106.0 1.6 1.8 2 1 0 2 2 2 1 Ribosomal protein L24e Flu_M1 PF00598.14 OAJ26848.1 - 0.05 13.0 0.2 0.07 12.5 0.2 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) DUF2116 PF09889.4 OAJ26848.1 - 1.1 9.0 5.7 4.2 7.2 0.5 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) WD40 PF00400.27 OAJ26849.1 - 5.8e-55 181.3 13.0 1.8e-11 43.4 0.0 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat PRP4 PF08799.6 OAJ26849.1 - 3.2e-13 48.6 3.0 5.7e-13 47.8 2.1 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 OAJ26849.1 - 0.00013 21.1 0.1 0.0078 15.3 0.0 3.0 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 OAJ26849.1 - 0.19 9.8 1.8 4.8 5.1 0.0 2.8 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Nucleopor_Nup85 PF07575.8 OAJ26850.1 - 3.9e-70 236.6 0.0 4.8e-37 127.4 0.0 2.3 2 1 0 2 2 2 2 Nup85 Nucleoporin Lsr2 PF11774.3 OAJ26850.1 - 3.6 7.5 7.8 1.4 8.8 0.2 2.9 3 0 0 3 3 3 0 Lsr2 Myosin_tail_1 PF01576.14 OAJ26851.1 - 6e-16 57.3 251.7 7.1e-05 20.7 33.6 6.8 1 1 3 5 5 5 5 Myosin tail Tropomyosin PF00261.15 OAJ26851.1 - 0.0025 16.9 21.7 0.0025 16.9 15.0 9.3 3 1 6 9 9 9 4 Tropomyosin Filament PF00038.16 OAJ26851.1 - 1.3 8.4 206.0 0.055 12.9 13.4 10.3 1 1 6 8 8 8 0 Intermediate filament protein PMT PF02366.13 OAJ26852.1 - 1.8e-74 250.2 17.2 3.3e-74 249.3 11.9 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 OAJ26852.1 - 1.6e-11 44.0 2.3 4.9e-10 39.2 0.6 2.7 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 OAJ26852.1 - 1e-05 25.5 11.2 1e-05 25.5 7.8 2.8 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF1935 PF09149.5 OAJ26853.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) Nop14 PF04147.7 OAJ26854.1 - 7 4.4 27.8 0.71 7.7 5.2 2.1 2 0 0 2 2 2 0 Nop14-like family NUDIX PF00293.23 OAJ26855.1 - 4.1e-07 29.7 0.1 1.7e-05 24.4 0.1 2.6 2 1 0 2 2 2 2 NUDIX domain Sec7 PF01369.15 OAJ26856.1 - 1.8e-64 216.9 0.0 4e-64 215.7 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 OAJ26856.1 - 3.6e-52 176.1 6.8 3.6e-52 176.1 4.7 2.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 OAJ26856.1 - 6.8e-25 86.4 0.3 3.1e-23 81.1 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) DUF3730 PF12530.3 OAJ26856.1 - 0.0023 17.8 0.2 0.0023 17.8 0.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3730) RFC1 PF08519.7 OAJ26857.1 - 4.7e-50 169.3 0.0 1.5e-49 167.7 0.0 1.9 2 0 0 2 2 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 OAJ26857.1 - 3.3e-10 39.9 0.0 7.1e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 OAJ26857.1 - 1.5e-09 38.1 0.0 4.3e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 OAJ26857.1 - 2.7e-07 29.6 0.1 8.3e-06 24.7 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 OAJ26857.1 - 0.00014 22.6 0.1 0.00056 20.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 OAJ26857.1 - 0.00078 19.3 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ26857.1 - 0.00084 19.4 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ26857.1 - 0.00094 19.4 0.1 0.0028 17.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 OAJ26857.1 - 0.0016 18.1 0.0 0.0047 16.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 OAJ26857.1 - 0.0017 18.3 0.0 0.0038 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 OAJ26857.1 - 0.003 16.6 0.0 0.0058 15.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 OAJ26857.1 - 0.0047 16.4 0.3 0.036 13.5 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_33 PF13671.1 OAJ26857.1 - 0.02 14.7 0.0 0.09 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 OAJ26857.1 - 0.028 14.0 0.1 0.079 12.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 OAJ26857.1 - 0.074 12.7 0.5 0.2 11.3 0.1 1.9 2 0 0 2 2 1 0 NTPase AAA_28 PF13521.1 OAJ26857.1 - 0.076 12.9 0.1 0.55 10.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 OAJ26857.1 - 0.078 12.6 0.0 0.49 10.0 0.0 2.2 1 1 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 OAJ26857.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 OAJ26857.1 - 0.21 11.1 1.9 0.42 10.1 0.0 2.1 1 1 1 2 2 2 0 AAA domain ECR1_N PF14382.1 OAJ26858.1 - 6.1e-06 25.4 0.0 1.7e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 OAJ26858.1 - 0.0053 16.6 0.0 0.12 12.3 0.0 2.6 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 FAD_binding_2 PF00890.19 OAJ26859.1 - 5.6e-33 114.4 0.0 9.1e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 OAJ26859.1 - 1.3e-21 76.1 0.2 3.1e-21 74.9 0.1 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF756 PF05506.7 OAJ26859.1 - 0.0069 16.8 0.8 0.014 15.8 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF756) Chorion_2 PF03964.10 OAJ26859.1 - 0.017 15.6 3.3 0.034 14.6 2.3 1.4 1 0 0 1 1 1 0 Chorion family 2 RVP_2 PF08284.6 OAJ26866.1 - 1.7e-10 40.9 0.0 2.6e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAJ26866.1 - 7.1e-08 32.8 0.0 1.3e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ26866.1 - 1.4e-05 24.8 0.1 3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 OAJ26866.1 - 0.0029 16.9 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 OAJ26866.1 - 0.049 13.5 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease SoxG PF04268.7 OAJ26866.1 - 0.099 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family Asp_protease PF09668.5 OAJ26866.1 - 0.19 11.3 0.0 0.69 9.4 0.0 1.8 1 1 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.12 OAJ26868.1 - 8.2e-12 45.0 0.2 2e-11 43.8 0.1 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAJ26868.1 - 0.055 13.4 0.2 0.091 12.7 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle RNase_H PF00075.19 OAJ26869.1 - 7.5e-19 68.3 0.0 1e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 RNase H DUF4581 PF15167.1 OAJ26869.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) RVT_1 PF00078.22 OAJ26870.1 - 7.6e-25 87.5 0.0 1.3e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ26870.1 - 2.3e-18 65.9 0.1 4.6e-18 64.9 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ26870.1 - 3.8e-08 33.5 0.4 7.9e-08 32.5 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 OAJ26871.1 - 0.00029 20.0 0.0 0.065 12.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ26871.1 - 0.0041 16.2 0.0 0.25 10.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase GMC_oxred_N PF00732.14 OAJ26872.1 - 0.11 11.6 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 GMC oxidoreductase WD40 PF00400.27 OAJ26873.1 - 1.9e-50 166.9 13.3 4.1e-09 35.9 0.2 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat Tannase PF07519.6 OAJ26873.1 - 2.1e-47 161.9 0.0 3.1e-38 131.7 0.1 3.2 1 1 1 2 2 2 2 Tannase and feruloyl esterase Nup160 PF11715.3 OAJ26873.1 - 0.014 13.6 0.2 4.8 5.1 0.0 3.5 1 1 2 3 3 3 0 Nucleoporin Nup120/160 MFS_1 PF07690.11 OAJ26876.1 - 7.6e-29 100.5 30.9 9.9e-29 100.1 21.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SNF2_N PF00176.18 OAJ26878.1 - 1.5e-63 214.3 1.1 3.6e-36 124.5 0.2 3.0 3 0 0 3 3 3 3 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ26878.1 - 3.6e-10 39.5 0.0 7.4e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SDA1 PF05285.7 OAJ26878.1 - 0.14 11.3 24.3 0.059 12.6 7.2 2.6 3 0 0 3 3 3 0 SDA1 DUF2890 PF11081.3 OAJ26878.1 - 2.7 8.0 17.5 0.23 11.4 5.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) BUD22 PF09073.5 OAJ26878.1 - 6.5 5.7 29.0 3.4 6.6 5.9 2.2 2 0 0 2 2 2 0 BUD22 PPP4R2 PF09184.6 OAJ26878.1 - 8 5.9 23.4 0.28 10.7 5.2 2.4 2 0 0 2 2 2 0 PPP4R2 RmlD_sub_bind PF04321.12 OAJ26880.1 - 0.038 12.8 0.2 0.078 11.8 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Cornifin PF02389.10 OAJ26880.1 - 0.094 12.4 8.9 0.12 12.1 6.2 1.2 1 0 0 1 1 1 0 Cornifin (SPRR) family SR-25 PF10500.4 OAJ26880.1 - 0.38 10.2 15.5 0.52 9.7 10.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 OAJ26880.1 - 0.86 7.8 6.8 1 7.5 4.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Apt1 PF10351.4 OAJ26880.1 - 0.9 8.3 2.9 1.1 8.0 2.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pol_alpha_B_N PF08418.5 OAJ26880.1 - 0.93 8.9 7.8 1.2 8.6 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal TMEM154 PF15102.1 OAJ26880.1 - 4.3 7.0 6.5 7.2 6.3 4.5 1.3 1 0 0 1 1 1 0 TMEM154 protein family SIP1 PF04938.7 OAJ26881.1 - 7.2e-16 58.2 0.4 3.3e-12 46.2 0.1 3.1 3 0 0 3 3 3 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Shadoo PF14999.1 OAJ26881.1 - 0.45 10.3 6.3 1.1 9.1 4.4 1.6 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective PH_BEACH PF14844.1 OAJ26881.1 - 2.7 7.8 5.1 0.89 9.4 0.4 2.4 3 0 0 3 3 3 0 PH domain associated with Beige/BEACH Pex14_N PF04695.8 OAJ26881.1 - 4.7 7.2 10.5 3.5 7.6 3.6 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RRM_6 PF14259.1 OAJ26882.1 - 1.2e-06 28.4 0.0 2.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 OAJ26882.1 - 0.00013 21.5 8.4 0.00037 20.1 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ26882.1 - 0.38 10.5 9.6 0.8 9.4 6.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 OAJ26882.1 - 4.2 7.1 10.4 9.5 5.9 7.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Formyl_trans_N PF00551.14 OAJ26883.1 - 5.2e-37 127.1 0.0 5.1e-34 117.3 0.0 2.4 1 1 0 1 1 1 1 Formyl transferase MAS20 PF02064.10 OAJ26883.1 - 4.2e-12 46.0 0.0 2.6e-11 43.4 0.0 2.0 1 1 0 1 1 1 1 MAS20 protein import receptor Myosin_head PF00063.16 OAJ26884.1 - 4.2e-248 824.9 0.0 4.2e-248 824.9 0.0 2.0 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 OAJ26884.1 - 2e-06 25.8 57.0 2e-06 25.8 39.5 3.5 1 1 2 3 3 3 2 Myosin tail Myosin_N PF02736.14 OAJ26884.1 - 0.00011 21.8 0.3 0.00029 20.4 0.2 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 OAJ26884.1 - 0.0081 15.8 1.0 0.038 13.7 0.7 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 OAJ26884.1 - 0.16 12.0 0.0 0.16 12.0 0.0 4.8 4 1 1 6 6 6 0 AAA domain IQ PF00612.22 OAJ26884.1 - 0.22 11.2 4.2 0.51 10.1 0.9 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF4206 PF13901.1 OAJ26884.1 - 2.3 7.7 0.0 2.3 7.7 0.0 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4206) Aconitase PF00330.15 OAJ26885.1 - 3.8e-180 599.3 0.0 4.7e-180 599.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAJ26885.1 - 6.6e-44 149.1 0.0 1.3e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain YPEB PF14620.1 OAJ26886.1 - 0.047 12.7 0.6 0.091 11.7 0.2 1.5 2 0 0 2 2 2 0 YpeB sporulation HAUS-augmin3 PF14932.1 OAJ26886.1 - 0.12 11.5 3.5 0.21 10.7 0.3 2.2 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 HLH PF00010.21 OAJ26887.1 - 0.00011 21.8 0.0 0.018 14.7 0.4 2.4 2 0 0 2 2 2 2 Helix-loop-helix DNA-binding domain PAT1 PF09770.4 OAJ26887.1 - 1.8 6.6 37.5 2.1 6.4 0.4 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.3 OAJ26887.1 - 5.1 6.3 12.2 6.8 5.9 0.2 2.2 2 0 0 2 2 2 0 Spt20 family rve PF00665.21 OAJ26889.1 - 4.5e-20 71.9 0.0 8.5e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 OAJ26889.1 - 9e-16 57.2 0.2 1.8e-15 56.3 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 OAJ26889.1 - 1e-13 51.1 0.0 1.9e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 OAJ26889.1 - 0.00075 18.8 0.0 0.0016 17.7 0.0 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Mtf2_C PF14061.1 OAJ26889.1 - 0.3 11.0 0.6 0.67 9.8 0.4 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 zf-DHHC PF01529.15 OAJ26890.1 - 0.28 10.5 8.1 1.9 7.8 2.5 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase Ribosomal_L7Ae PF01248.21 OAJ26892.1 - 1.1e-21 76.1 0.2 1.7e-21 75.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 OAJ26892.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 Arch_ATPase PF01637.13 OAJ26892.1 - 0.11 12.2 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Archaeal ATPase RhoGEF PF00621.15 OAJ26893.1 - 5.6e-16 58.9 0.1 2.6e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain DDE_3 PF13358.1 OAJ26894.1 - 0.023 14.4 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Cu-oxidase_3 PF07732.10 OAJ26895.1 - 1.4e-38 131.2 2.6 1.4e-38 131.2 1.8 3.4 4 1 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAJ26895.1 - 5.5e-35 119.8 11.6 3e-33 114.2 0.4 3.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 OAJ26895.1 - 4.6e-30 104.6 0.3 3.6e-28 98.4 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase Nucleoplasmin PF03066.10 OAJ26896.1 - 0.0092 15.5 2.7 0.016 14.7 1.9 1.3 1 0 0 1 1 1 1 Nucleoplasmin Senescence_reg PF04520.8 OAJ26896.1 - 0.02 15.4 2.9 0.02 15.4 2.0 1.9 2 0 0 2 2 2 0 Senescence regulator PBP1_TM PF14812.1 OAJ26896.1 - 0.16 12.3 12.7 0.034 14.4 5.7 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 OAJ26896.1 - 0.37 8.6 1.8 0.46 8.3 1.2 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 OAJ26896.1 - 0.39 10.3 4.5 0.66 9.6 3.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein gpUL132 PF11359.3 OAJ26896.1 - 0.62 9.3 3.0 1.2 8.3 2.1 1.5 1 0 0 1 1 1 0 Glycoprotein UL132 PGA2 PF07543.7 OAJ26896.1 - 1.7 8.4 4.0 3.2 7.5 2.8 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Sigma70_ner PF04546.8 OAJ26896.1 - 1.7 8.2 5.5 2.9 7.4 3.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region BAF1_ABF1 PF04684.8 OAJ26896.1 - 2.4 6.9 13.0 3.1 6.5 1.5 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor CENP-B_dimeris PF09026.5 OAJ26896.1 - 8.9 6.6 12.2 20 5.5 8.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cu-oxidase_3 PF07732.10 OAJ26897.1 - 5.9e-38 129.2 6.7 3e-36 123.7 2.4 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAJ26897.1 - 3.5e-29 101.0 5.0 8.3e-25 86.8 0.0 3.9 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 OAJ26897.1 - 3.7e-24 85.4 0.0 9.4e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase PIG-U PF06728.8 OAJ26898.1 - 5.4e-93 311.8 15.7 6.5e-93 311.6 10.9 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Chromo PF00385.19 OAJ26898.1 - 1.9e-08 33.8 3.1 3.3e-08 33.0 2.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 OAJ26898.1 - 7.7e-07 28.8 0.0 2.6e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Chromo shadow domain Mannosyl_trans PF05007.8 OAJ26898.1 - 0.0036 16.9 4.5 0.0079 15.8 3.1 1.5 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) DEAD PF00270.24 OAJ26899.1 - 6.7e-30 103.7 0.0 5.7e-29 100.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ26899.1 - 5e-18 64.7 0.1 1.5e-16 60.0 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Glyco_hydro_35 PF01301.14 OAJ26900.1 - 5.3e-70 236.2 0.0 8.2e-70 235.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 OAJ26900.1 - 1.2e-34 118.8 0.1 9.6e-19 67.6 0.0 2.5 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 OAJ26900.1 - 4.7e-27 94.5 0.0 7.4e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 OAJ26900.1 - 2.1e-07 30.2 0.0 5.1e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 OAJ26900.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) TPR_11 PF13414.1 OAJ26901.1 - 2.7e-26 90.9 15.6 2.4e-11 43.1 0.1 6.7 5 1 2 7 7 7 5 TPR repeat TPR_2 PF07719.12 OAJ26901.1 - 3.9e-16 57.5 26.0 0.011 15.6 0.0 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ26901.1 - 7e-15 53.9 12.6 1.8e-05 24.1 0.0 7.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ26901.1 - 1.6e-13 50.8 10.3 6.3e-06 26.7 0.4 8.4 6 1 4 10 10 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ26901.1 - 2.8e-10 40.3 12.1 4.3e-06 26.9 0.4 6.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ26901.1 - 3.6e-10 39.2 0.3 0.66 10.3 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ26901.1 - 7.2e-10 38.6 40.6 0.024 15.2 0.1 10.3 7 1 4 11 11 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ26901.1 - 5.1e-07 29.0 0.1 0.97 9.3 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ26901.1 - 1.7e-06 27.8 4.6 0.0003 20.6 0.7 6.4 4 1 5 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 OAJ26901.1 - 0.0027 17.8 11.9 1.1 9.4 0.0 5.1 4 1 3 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 OAJ26901.1 - 0.0072 16.1 0.8 0.0072 16.1 0.5 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ26901.1 - 0.12 12.2 18.6 0.33 10.8 0.1 6.7 8 1 1 9 9 8 0 Tetratricopeptide repeat Nop14 PF04147.7 OAJ26901.1 - 8.8 4.1 36.6 13 3.5 25.4 1.1 1 0 0 1 1 1 0 Nop14-like family Peptidase_M41 PF01434.13 OAJ26907.1 - 5.5e-71 238.4 1.9 6.5e-71 238.1 0.4 1.7 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 OAJ26907.1 - 2.5e-42 144.1 0.0 6.6e-42 142.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 OAJ26907.1 - 2.1e-10 40.7 0.0 7.1e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.1 OAJ26907.1 - 0.00026 21.1 0.0 0.18 11.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 OAJ26907.1 - 0.0045 15.7 0.0 0.007 15.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 OAJ26907.1 - 0.0046 16.3 2.4 0.025 13.9 0.3 2.8 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.1 OAJ26907.1 - 0.0047 16.6 0.2 0.0047 16.6 0.1 2.5 2 0 0 2 2 1 1 Part of AAA domain AAA_5 PF07728.9 OAJ26907.1 - 0.0088 15.7 0.1 0.074 12.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 OAJ26907.1 - 0.0098 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 OAJ26907.1 - 0.013 15.5 0.2 0.13 12.2 0.1 2.5 1 1 1 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 OAJ26907.1 - 0.017 15.9 0.0 0.059 14.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 OAJ26907.1 - 0.02 13.9 0.0 0.047 12.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.7 OAJ26907.1 - 0.067 12.2 1.6 0.069 12.1 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Collagen PF01391.13 OAJ26908.1 - 5.2e-24 83.5 152.3 4.5e-07 29.3 18.1 5.4 1 1 3 4 4 4 3 Collagen triple helix repeat (20 copies) RNA_pol_3_Rpc31 PF11705.3 OAJ26909.1 - 0.88 9.4 12.2 1.6 8.6 8.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.9 OAJ26909.1 - 1.2 8.6 7.4 2.4 7.6 5.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HEAT_2 PF13646.1 OAJ26910.1 - 1.5e-24 86.0 3.8 1.2e-13 51.1 0.3 4.4 2 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 OAJ26910.1 - 2.3e-11 42.7 2.0 0.2 11.8 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat HEAT_PBS PF03130.11 OAJ26910.1 - 7.5e-11 41.4 8.4 0.0096 16.3 0.0 7.4 8 0 0 8 8 8 3 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 OAJ26910.1 - 1.4e-05 25.4 3.5 0.026 14.9 0.1 5.9 5 2 2 7 7 7 3 HEAT-like repeat Arm PF00514.18 OAJ26910.1 - 0.0058 16.4 0.0 1.2 9.0 0.0 2.9 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat ABC_membrane PF00664.18 OAJ26911.1 - 1.7e-43 149.0 34.5 3.2e-28 98.9 11.4 3.6 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ26911.1 - 1.4e-40 138.7 0.0 5.8e-26 91.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAJ26911.1 - 4.1e-09 35.9 1.0 0.004 16.3 0.0 4.5 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAJ26911.1 - 4.7e-05 23.8 0.0 0.19 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAJ26911.1 - 0.00013 21.4 0.4 0.17 11.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 OAJ26911.1 - 0.00021 20.7 0.6 0.89 8.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 OAJ26911.1 - 0.003 17.0 0.4 2.3 7.5 0.1 2.7 2 1 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 OAJ26911.1 - 0.012 15.7 2.0 3.6 7.7 0.0 3.6 4 0 0 4 4 4 0 AAA domain DUF87 PF01935.12 OAJ26911.1 - 0.013 15.3 1.6 0.014 15.2 0.1 1.8 2 0 0 2 2 1 0 Domain of unknown function DUF87 AAA_21 PF13304.1 OAJ26911.1 - 0.037 13.9 1.4 2.2 8.1 0.0 3.2 3 1 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 OAJ26911.1 - 0.048 13.1 0.2 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 OAJ26911.1 - 0.12 12.5 0.2 4.2 7.5 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 OAJ26911.1 - 0.13 13.0 0.0 0.48 11.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 OAJ26911.1 - 0.15 11.2 0.2 12 5.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 OAJ26911.1 - 0.19 12.2 1.2 3.1 8.2 0.2 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 OAJ26911.1 - 0.69 9.8 5.9 0.24 11.3 0.2 2.8 2 2 0 2 2 2 0 AAA ATPase domain Zn_clus PF00172.13 OAJ26912.1 - 1.2e-05 25.0 7.3 2.5e-05 24.1 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4164 PF13747.1 OAJ26914.1 - 0.0038 17.3 4.5 0.013 15.6 2.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4164) Apolipoprotein PF01442.13 OAJ26914.1 - 0.0091 15.5 3.3 0.013 15.0 2.3 1.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ISG65-75 PF11727.3 OAJ26914.1 - 0.013 14.5 0.3 0.016 14.3 0.2 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Dzip-like_N PF13815.1 OAJ26914.1 - 0.022 14.5 0.5 0.028 14.2 0.4 1.1 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal AATF-Che1 PF13339.1 OAJ26914.1 - 0.048 13.8 1.5 0.059 13.5 1.0 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Exotox-A_bind PF09101.5 OAJ26914.1 - 0.095 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Exotoxin A binding COG5 PF10392.4 OAJ26914.1 - 0.14 12.0 1.5 0.2 11.6 0.7 1.5 1 1 0 1 1 1 0 Golgi transport complex subunit 5 DUF883 PF05957.8 OAJ26914.1 - 1.1 9.6 7.3 1.2 9.6 1.0 2.4 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Histone PF00125.19 OAJ26915.1 - 3.4e-20 71.9 0.1 5.3e-20 71.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 HhH-GPD PF00730.20 OAJ26916.1 - 2.2e-12 47.1 0.0 4.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein TraG-D_C PF12696.2 OAJ26916.1 - 1.6 8.6 3.7 25 4.7 2.8 2.2 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG PLA2_B PF01735.13 OAJ26917.1 - 2.1e-12 45.9 0.0 1.4e-06 26.7 0.9 2.6 2 1 0 2 2 2 2 Lysophospholipase catalytic domain Metallophos_2 PF12850.2 OAJ26918.1 - 1.1e-19 70.8 0.0 1.7e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 OAJ26918.1 - 0.00056 19.3 1.5 0.015 14.6 0.0 2.2 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase TFIIF_alpha PF05793.7 OAJ26918.1 - 2.5 6.3 18.7 3.4 5.9 13.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Epimerase PF01370.16 OAJ26920.1 - 4.9e-06 26.1 0.0 0.1 12.0 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 OAJ26920.1 - 0.0011 19.2 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 OAJ26920.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Glyco_tran_WecB PF03808.8 OAJ26920.1 - 0.044 13.1 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family adh_short PF00106.20 OAJ26920.1 - 0.045 13.6 0.4 0.17 11.7 0.0 2.0 2 1 0 2 2 2 0 short chain dehydrogenase KR PF08659.5 OAJ26920.1 - 0.11 12.1 0.5 0.32 10.6 0.4 1.8 1 1 0 1 1 1 0 KR domain Apc3 PF12895.2 OAJ26924.1 - 7.4e-08 32.4 5.4 0.3 11.2 0.1 5.4 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 OAJ26924.1 - 1.6e-05 25.1 26.0 0.69 10.7 0.2 9.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ26924.1 - 5.7e-05 22.6 17.3 0.0036 16.9 0.1 6.1 6 0 0 6 6 6 2 TPR repeat TPR_12 PF13424.1 OAJ26924.1 - 0.00017 21.4 39.5 0.011 15.6 2.5 7.4 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ26924.1 - 0.00031 21.3 24.1 0.014 16.0 4.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc5 PF12862.2 OAJ26924.1 - 0.023 14.5 9.0 4.2 7.2 0.2 4.9 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_2 PF07719.12 OAJ26924.1 - 0.036 13.9 29.7 3.3 7.8 0.7 8.8 10 0 0 10 10 9 0 Tetratricopeptide repeat CK_II_beta PF01214.13 OAJ26924.1 - 0.069 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Casein kinase II regulatory subunit TPR_1 PF00515.23 OAJ26924.1 - 1.4 8.6 13.7 2 8.1 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat PBP1_TM PF14812.1 OAJ26924.1 - 4.6 7.6 11.7 0.3 11.4 4.1 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_19 PF14559.1 OAJ26924.1 - 9.6 6.6 25.6 2.7 8.3 0.1 6.5 5 2 2 7 7 7 0 Tetratricopeptide repeat DUF3246 PF11596.3 OAJ26925.1 - 0.03 13.6 0.1 11 5.2 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) SDA1 PF05285.7 OAJ26927.1 - 0.0007 18.9 4.1 0.0007 18.9 2.8 3.4 3 0 0 3 3 3 2 SDA1 SRP-alpha_N PF04086.8 OAJ26928.1 - 4.4 6.5 24.0 0.18 11.1 9.1 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal PHD PF00628.24 OAJ26929.1 - 3.3e-13 49.0 20.1 1.6e-08 34.0 6.3 2.9 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.1 OAJ26929.1 - 4.2 6.6 5.7 0.91 8.7 1.4 1.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Glyco_transf_28 PF03033.15 OAJ26930.1 - 9.8e-25 86.9 0.0 2.2e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 OAJ26930.1 - 1.7e-05 24.2 0.0 0.37 10.3 0.0 2.9 3 0 0 3 3 3 2 GRAM domain UDPGT PF00201.13 OAJ26930.1 - 0.0027 16.3 0.0 0.0045 15.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.24 OAJ26930.1 - 0.0043 17.2 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 PH domain SUZ PF12752.2 OAJ26931.1 - 1.1e-10 41.9 1.8 1.1e-10 41.9 1.2 2.8 3 1 0 3 3 3 1 SUZ domain p450 PF00067.17 OAJ26932.1 - 1.7e-57 195.0 0.0 3.2e-57 194.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_cc PF11790.3 OAJ26934.1 - 3.1e-40 138.0 0.1 4.3e-40 137.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core SOG2 PF10428.4 OAJ26934.1 - 0.04 12.5 0.4 0.05 12.2 0.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Zip PF02535.17 OAJ26934.1 - 0.062 12.2 17.5 0.1 11.5 12.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RhoGAP PF00620.22 OAJ26935.1 - 2.3e-35 121.4 0.0 3.6e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DPBB_1 PF03330.13 OAJ26936.1 - 1.1e-11 44.5 0.1 2.1e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel PBP PF01161.15 OAJ26937.1 - 9.2e-22 77.4 0.2 1.7e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein WD40 PF00400.27 OAJ26939.1 - 5.8e-75 244.7 15.1 6.6e-14 51.1 0.1 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 OAJ26939.1 - 2.5e-10 39.1 17.1 0.0045 15.1 0.2 5.5 2 1 3 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAJ26939.1 - 7.2e-05 21.7 1.9 2 7.0 0.0 4.2 1 1 3 5 5 5 4 Nup133 N terminal like eIF2A PF08662.6 OAJ26939.1 - 0.013 15.2 0.0 3.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 OAJ26939.1 - 0.031 12.5 0.2 2 6.6 0.0 2.3 2 1 0 2 2 2 0 Cytochrome D1 heme domain DUF1652 PF07865.6 OAJ26939.1 - 0.073 12.6 0.0 19 4.9 0.0 4.1 6 0 0 6 6 6 0 Protein of unknown function (DUF1652) Enolase_C PF00113.17 OAJ26940.1 - 1e-143 477.7 0.2 1.3e-143 477.3 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 OAJ26940.1 - 9.4e-57 190.6 0.2 1.7e-56 189.7 0.1 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 OAJ26940.1 - 6.2e-05 22.9 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 OAJ26940.1 - 0.0074 15.2 0.1 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 OAJ26940.1 - 0.06 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain APC10 PF03256.11 OAJ26941.1 - 3.7e-42 144.1 1.1 4.9e-42 143.7 0.0 1.7 2 1 0 2 2 2 1 Anaphase-promoting complex, subunit 10 (APC10) PAT1 PF09770.4 OAJ26941.1 - 3.3 5.8 10.9 4.3 5.4 7.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Chitin_synth_2 PF03142.10 OAJ26942.1 - 7.4e-239 793.5 0.1 7.4e-239 793.5 0.1 1.6 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.16 OAJ26942.1 - 4.5e-150 500.9 0.0 7.2e-150 500.2 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 OAJ26942.1 - 4.5e-18 65.6 0.9 1.2e-17 64.2 0.2 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 OAJ26942.1 - 6.8e-15 54.6 0.0 8.9e-07 28.6 0.0 2.9 2 1 1 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 OAJ26942.1 - 1.6e-13 50.9 0.0 6.5e-10 39.2 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DEK_C PF08766.6 OAJ26942.1 - 1.7e-13 50.1 1.6 4.4e-12 45.5 0.0 3.4 4 0 0 4 4 4 1 DEK C terminal domain Glycos_transf_2 PF00535.21 OAJ26942.1 - 0.00013 21.6 0.0 0.014 15.1 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 OAJ26942.1 - 0.028 13.6 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 21 AAA_16 PF13191.1 OAJ26942.1 - 0.06 13.3 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 OAJ26942.1 - 0.15 11.1 0.0 0.38 9.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 OAJ26942.1 - 0.17 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CMAS PF02353.15 OAJ26951.1 - 7.5e-34 117.0 0.4 3.4e-33 114.8 0.3 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 OAJ26951.1 - 2.2e-11 44.0 0.0 4.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ26951.1 - 1.8e-10 40.6 0.0 5.2e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ26951.1 - 2.7e-07 30.4 0.0 6.2e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ26951.1 - 9.5e-07 29.3 0.0 3.7e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ26951.1 - 7.1e-06 26.4 0.0 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ26951.1 - 7.2e-06 25.4 0.0 1.6e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 OAJ26951.1 - 1.5e-05 25.2 0.0 4.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 OAJ26951.1 - 0.0028 16.7 0.0 0.005 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.10 OAJ26951.1 - 0.017 14.2 0.0 0.037 13.1 0.0 1.5 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G TehB PF03848.9 OAJ26951.1 - 0.025 13.7 0.1 0.091 11.9 0.0 1.8 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 OAJ26951.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 OAJ26951.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Pmp3 PF01679.12 OAJ26952.1 - 2e-21 75.4 6.8 2.3e-21 75.2 4.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Ada3 PF10198.4 OAJ26953.1 - 1.1e-26 93.1 2.2 2.5e-26 91.9 0.0 2.4 2 1 0 2 2 2 1 Histone acetyltransferases subunit 3 Histone PF00125.19 OAJ26955.1 - 1.3e-25 89.2 0.0 1.8e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAJ26955.1 - 1.2e-05 25.3 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FAP PF07174.6 OAJ26956.1 - 0.038 13.3 1.4 0.046 13.0 1.0 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Macoilin PF09726.4 OAJ26957.1 - 1.8 6.7 5.1 1.9 6.6 3.6 1.0 1 0 0 1 1 1 0 Transmembrane protein DLIC PF05783.6 OAJ26957.1 - 3.8 6.0 6.3 5 5.6 4.4 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF2413 PF10310.4 OAJ26957.1 - 4.2 6.0 6.5 5.5 5.6 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) F-box-like PF12937.2 OAJ26958.1 - 3.3e-09 36.3 0.3 7.3e-09 35.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ26958.1 - 7.2e-09 35.0 0.3 1.7e-08 33.9 0.2 1.7 1 0 0 1 1 1 1 F-box domain WH1 PF00568.18 OAJ26959.1 - 6e-13 48.4 0.0 2.6e-12 46.4 0.0 2.0 2 1 0 2 2 2 1 WH1 domain PBD PF00786.23 OAJ26959.1 - 9.3e-09 35.5 0.0 2.6e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain DUF605 PF04652.11 OAJ26959.1 - 0.00062 19.2 8.5 0.00062 19.2 5.9 2.1 2 0 0 2 2 2 1 Vta1 like WH2 PF02205.15 OAJ26959.1 - 0.0015 18.0 0.1 0.0036 16.8 0.1 1.7 1 0 0 1 1 1 1 WH2 motif EFG_C PF00679.19 OAJ26959.1 - 0.023 14.5 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Elongation factor G C-terminus Lactamase_B_2 PF12706.2 OAJ26960.1 - 1.4e-20 73.7 0.0 4.2e-20 72.1 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 OAJ26960.1 - 5e-10 38.7 0.0 1.2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 OAJ26960.1 - 5.3e-06 26.2 0.1 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily UPF0160 PF03690.8 OAJ26961.1 - 1e-122 409.5 0.0 1.8e-122 408.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) RNase_H2-Ydr279 PF09468.5 OAJ26961.1 - 6.7e-19 68.1 0.1 6.9e-10 38.5 0.5 4.0 2 1 0 2 2 2 2 Ydr279p protein family (RNase H2 complex component) zf-BED PF02892.10 OAJ26962.1 - 0.0052 16.5 1.6 0.0094 15.6 1.1 1.4 1 0 0 1 1 1 1 BED zinc finger DUF4207 PF13904.1 OAJ26964.1 - 0.034 13.5 4.8 0.051 12.9 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DUF4398 PF14346.1 OAJ26965.1 - 0.046 13.7 1.2 0.088 12.8 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) BUD22 PF09073.5 OAJ26966.1 - 0.49 9.4 3.9 0.73 8.8 2.7 1.1 1 0 0 1 1 1 0 BUD22 DEAD PF00270.24 OAJ26969.1 - 1.3e-12 47.5 0.0 2.8e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ26969.1 - 7e-09 35.4 0.0 3.9e-08 33.0 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain MFS_1 PF07690.11 OAJ26970.1 - 1.1e-17 63.8 46.4 1.1e-17 63.8 32.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 OAJ26970.1 - 0.02 14.6 0.3 0.02 14.6 0.2 3.1 3 1 0 3 3 3 0 MFS_1 like family Zn_clus PF00172.13 OAJ26972.1 - 1.4 8.9 5.9 5.3 7.0 4.1 1.9 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain JAB PF01398.16 OAJ26973.1 - 1e-26 92.9 0.1 1.6e-26 92.2 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 OAJ26973.1 - 2.4e-06 27.0 0.0 4.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 OAJ26973.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) TFIIF_alpha PF05793.7 OAJ26973.1 - 1.2 7.4 7.3 1.6 6.9 5.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2360 PF10152.4 OAJ26973.1 - 7.9 6.7 7.7 8.1 6.7 2.1 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Apo-CII PF05355.6 OAJ26975.1 - 0.0049 16.6 0.0 0.017 14.9 0.0 1.9 2 0 0 2 2 2 1 Apolipoprotein C-II SIN1 PF05422.7 OAJ26976.1 - 2.6e-24 85.6 0.0 2.6e-13 49.3 0.0 2.6 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) MttA_Hcf106 PF02416.11 OAJ26977.1 - 0.097 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 mttA/Hcf106 family B56 PF01603.15 OAJ26979.1 - 4.2e-169 562.4 3.0 5e-169 562.2 2.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Hat1_N PF10394.4 OAJ26980.1 - 4e-35 121.2 0.0 8.7e-35 120.1 0.0 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 OAJ26980.1 - 0.001 19.1 0.0 0.0031 17.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAJ26980.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAJ26980.1 - 0.09 12.8 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MOZ_SAS PF01853.13 OAJ26980.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 MOZ/SAS family SWIB PF02201.13 OAJ26981.1 - 7.8e-17 60.7 0.0 1.5e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Sec66 PF09802.4 OAJ26982.1 - 1.2e-47 161.8 0.1 1.8e-47 161.2 0.1 1.3 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 EBV-NA3 PF05009.7 OAJ26982.1 - 0.047 12.9 5.1 0.74 9.0 0.0 2.3 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) FLO_LFY PF01698.11 OAJ26982.1 - 1.4 7.7 10.7 1.1 8.0 6.4 1.5 1 1 1 2 2 2 0 Floricaula / Leafy protein PPP4R2 PF09184.6 OAJ26982.1 - 1.6 8.2 11.8 2.4 7.6 8.2 1.2 1 0 0 1 1 1 0 PPP4R2 RR_TM4-6 PF06459.7 OAJ26982.1 - 1.8 8.3 12.3 2.9 7.7 8.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AMP-binding PF00501.23 OAJ26983.1 - 2.9e-78 263.1 0.0 4.6e-78 262.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 OAJ26983.1 - 3.6e-65 219.3 0.0 5.7e-65 218.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 OAJ26983.1 - 2.3e-13 50.2 0.0 5.7e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 OAJ26983.1 - 2.8e-09 37.7 0.0 9e-09 36.1 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 OAJ26983.1 - 1.3e-07 31.2 0.0 2.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAJ26983.1 - 0.004 15.8 0.0 0.18 10.4 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.15 OAJ26983.1 - 0.0042 15.9 0.0 0.058 12.2 0.0 2.2 2 0 0 2 2 2 1 Condensation domain Polysacc_synt_2 PF02719.10 OAJ26983.1 - 0.013 14.4 0.0 0.038 12.8 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PTPlike_phytase PF14566.1 OAJ26984.1 - 0.00013 22.0 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 OAJ26984.1 - 0.00022 20.8 0.0 0.00044 19.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 OAJ26984.1 - 0.00061 20.0 0.5 0.0031 17.7 0.0 2.3 2 1 1 3 3 3 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 OAJ26984.1 - 0.021 14.1 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Asp PF00026.18 OAJ26986.1 - 2e-60 204.6 1.2 2.5e-60 204.3 0.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ26986.1 - 1.1e-07 31.9 0.2 2e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 OAJ26986.1 - 0.06 12.8 0.0 0.25 10.8 0.0 2.0 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal EF-hand_1 PF00036.27 OAJ26987.1 - 4.2e-28 94.4 12.7 2.7e-08 32.5 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 OAJ26987.1 - 3.4e-25 87.9 10.9 6.3e-13 48.6 3.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 OAJ26987.1 - 4.4e-24 82.1 9.6 1.9e-07 30.3 0.0 4.3 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 OAJ26987.1 - 1.5e-20 72.5 12.3 6.2e-09 35.3 1.8 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 OAJ26987.1 - 7e-16 56.7 11.6 0.00016 20.8 1.0 4.2 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 OAJ26987.1 - 2.9e-12 46.3 0.3 2.5e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 OAJ26987.1 - 1.9e-06 27.5 1.9 0.034 13.8 0.4 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 OAJ26987.1 - 0.025 14.1 0.2 0.28 10.7 0.0 2.3 2 1 1 3 3 3 0 Caleosin related protein SPARC_Ca_bdg PF10591.4 OAJ26987.1 - 0.035 14.1 1.3 7.5 6.6 0.2 2.2 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DHHA1 PF02272.14 OAJ26987.1 - 0.26 10.9 4.8 0.67 9.7 1.1 2.5 2 1 0 2 2 2 0 DHHA1 domain MgtE_N PF03448.12 OAJ26987.1 - 0.33 11.2 3.2 0.45 10.8 0.9 2.0 2 0 0 2 2 2 0 MgtE intracellular N domain Toprim_2 PF13155.1 OAJ26987.1 - 0.36 11.1 2.2 15 6.0 0.1 2.4 1 1 1 2 2 2 0 Toprim-like SHOCT PF09851.4 OAJ26987.1 - 0.79 9.2 3.9 0.6 9.6 0.4 2.6 2 0 0 2 2 2 0 Short C-terminal domain His_biosynth PF00977.16 OAJ26988.1 - 1.1e-39 136.1 0.0 7.5e-24 84.2 0.0 2.9 2 1 0 2 2 2 2 Histidine biosynthesis protein GATase PF00117.23 OAJ26988.1 - 3.9e-22 78.6 0.0 7e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 OAJ26988.1 - 8.9e-09 35.1 0.1 2.6e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 OAJ26988.1 - 9.1e-07 28.6 0.0 4.6e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 OAJ26988.1 - 0.074 12.4 0.3 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 Kei1 PF08552.6 OAJ26989.1 - 5.4e-45 153.3 1.4 6.7e-45 153.0 0.9 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Abhydrolase_6 PF12697.2 OAJ26990.1 - 1.1e-22 81.0 1.7 2.3e-22 79.9 1.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ26990.1 - 3.1e-08 33.4 0.0 7.3e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ26990.1 - 1.5e-06 27.9 0.0 0.027 14.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAJ26990.1 - 0.00055 19.7 0.4 0.0012 18.6 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase DUF676 PF05057.9 OAJ26990.1 - 0.044 13.0 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) MFS_1 PF07690.11 OAJ26991.1 - 2.8e-18 65.7 10.9 2.8e-18 65.7 7.6 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily UQ_con PF00179.21 OAJ26992.1 - 8.7e-21 73.8 0.0 1.2e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DEAD PF00270.24 OAJ26998.1 - 5.2e-45 152.9 0.0 3.7e-44 150.1 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ26998.1 - 7.9e-23 80.1 0.0 2.3e-22 78.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ26998.1 - 0.0026 17.5 0.0 0.01 15.6 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2285 PF10074.4 OAJ26998.1 - 0.0077 16.5 4.8 0.029 14.7 1.6 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2285) CMS1 PF14617.1 OAJ26998.1 - 0.025 13.6 0.0 0.14 11.1 0.0 2.2 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Pilin_PilX PF11530.3 OAJ26998.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Minor type IV pilin, PilX Helicase_C_2 PF13307.1 OAJ26998.1 - 0.13 12.2 0.3 1.6 8.6 0.0 2.3 1 1 1 2 2 2 0 Helicase C-terminal domain zf-CCHC_2 PF13696.1 OAJ26998.1 - 0.13 11.7 0.8 0.36 10.3 0.6 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 OAJ26998.1 - 0.2 11.6 1.8 0.32 10.9 1.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ26998.1 - 0.25 11.0 1.3 0.55 9.9 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle AFG1_ATPase PF03969.11 OAJ26999.1 - 2.2e-85 286.6 0.0 1.7e-80 270.5 0.0 3.1 3 0 0 3 3 3 3 AFG1-like ATPase AAA_22 PF13401.1 OAJ26999.1 - 0.00012 22.2 0.0 0.00051 20.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ26999.1 - 0.0011 19.0 0.2 0.027 14.4 0.0 3.1 2 2 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 OAJ26999.1 - 0.036 14.2 0.0 2.8 8.1 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.16 OAJ26999.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain CDC27 PF09507.5 OAJ27000.1 - 1.3e-34 120.2 71.0 1.5e-21 77.1 0.0 4.2 1 1 2 3 3 3 3 DNA polymerase subunit Cdc27 Serglycin PF04360.7 OAJ27000.1 - 0.25 11.0 5.7 0.14 11.9 1.0 2.3 2 0 0 2 2 2 0 Serglycin DEAD PF00270.24 OAJ27001.1 - 3e-33 114.6 0.1 4.8e-32 110.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ27001.1 - 1.3e-25 89.0 0.2 2.2e-25 88.3 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 OAJ27001.1 - 3.9e-05 23.6 0.0 7.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain AAA_22 PF13401.1 OAJ27001.1 - 0.099 12.7 0.6 0.71 10.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain ThiF PF00899.16 OAJ27002.1 - 8e-45 151.9 0.1 1.6e-28 99.2 0.1 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 OAJ27002.1 - 7.4e-42 142.4 0.0 1.6e-41 141.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 OAJ27002.1 - 1.8e-41 139.5 5.7 1.2e-27 95.2 0.2 3.3 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 OAJ27002.1 - 6.2e-25 86.3 2.0 3.7e-21 74.2 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Pyr_redox PF00070.22 OAJ27002.1 - 0.54 10.7 2.1 44 4.5 0.0 3.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GATase PF00117.23 OAJ27003.1 - 2.7e-08 33.4 0.0 3.2e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 OAJ27003.1 - 0.057 12.8 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase C26 SUI1 PF01253.17 OAJ27004.1 - 1.3e-15 56.9 0.0 4.7e-15 55.1 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor SUI1 HTH_Tnp_1 PF01527.15 OAJ27004.1 - 0.093 12.6 3.4 3.2 7.7 2.4 2.9 1 1 0 1 1 1 0 Transposase AD PF09793.4 OAJ27005.1 - 8.6e-19 67.1 0.0 1.4e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain BCDHK_Adom3 PF10436.4 OAJ27007.1 - 5.9e-62 208.0 0.0 8.8e-62 207.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 OAJ27007.1 - 3e-19 68.7 0.0 5.2e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAJ27007.1 - 3.9e-06 26.5 0.0 6.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sugar_tr PF00083.19 OAJ27008.1 - 1.2e-20 73.5 18.6 2.3e-16 59.4 5.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ27008.1 - 2.9e-11 42.6 34.0 1e-10 40.8 23.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Pyr_redox_2 PF07992.9 OAJ27009.1 - 3.4e-22 79.3 0.7 1.8e-21 76.9 0.5 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 OAJ27009.1 - 1.9e-14 52.9 0.0 3.8e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 OAJ27009.1 - 6.6e-13 48.8 8.2 3.2e-11 43.4 0.2 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 OAJ27009.1 - 6.8e-07 28.9 0.0 2.3e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox_3 PF13738.1 OAJ27009.1 - 3e-05 24.1 0.7 0.001 19.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 OAJ27009.1 - 0.0049 17.1 0.0 0.015 15.5 0.0 1.9 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.1 OAJ27009.1 - 0.009 14.9 0.2 9.8 4.9 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAJ27009.1 - 0.085 12.6 0.5 1.8 8.3 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Histone PF00125.19 OAJ27010.1 - 6.5e-29 99.8 0.4 1e-28 99.2 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ27010.1 - 0.059 13.5 0.1 0.093 12.9 0.1 1.3 1 0 0 1 1 1 0 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAJ27010.1 - 0.089 12.8 0.1 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mito_carr PF00153.22 OAJ27011.1 - 5.7e-56 186.2 1.6 6.1e-18 64.3 0.1 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein SNF2_N PF00176.18 OAJ27012.1 - 2e-81 273.0 0.0 3.4e-81 272.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 OAJ27012.1 - 8e-38 128.7 0.2 3.4e-37 126.7 0.1 2.2 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 OAJ27012.1 - 2.3e-30 105.2 3.5 2.3e-30 105.2 2.4 3.1 3 0 0 3 3 2 1 HAND Helicase_C PF00271.26 OAJ27012.1 - 2.4e-14 52.9 0.0 2e-13 50.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ27012.1 - 5.9e-09 36.0 0.0 5.5e-08 32.8 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ27012.1 - 2.7e-07 30.2 0.0 7.5e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HWE_HK PF07536.9 OAJ27012.1 - 0.0016 18.8 1.1 0.23 11.9 0.0 3.1 2 0 0 2 2 2 1 HWE histidine kinase Myb_DNA-binding PF00249.26 OAJ27012.1 - 0.0067 16.4 0.0 0.14 12.1 0.0 3.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain DEAD_2 PF06733.10 OAJ27012.1 - 0.0083 15.5 0.2 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 DBINO PF13892.1 OAJ27012.1 - 0.0084 16.1 5.0 0.0084 16.1 3.5 4.0 3 0 0 3 3 1 1 DNA-binding domain AAA_14 PF13173.1 OAJ27012.1 - 0.011 15.6 0.2 0.046 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 OAJ27012.1 - 0.079 13.1 1.0 0.27 11.3 0.1 2.4 3 0 0 3 3 3 0 AAA domain Mucin PF01456.12 OAJ27013.1 - 0.079 12.7 15.2 0.15 11.8 10.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SIR2 PF02146.12 OAJ27014.1 - 1.4e-25 90.0 0.1 3.9e-19 69.0 0.0 3.8 3 1 0 3 3 3 2 Sir2 family vMSA PF00695.14 OAJ27014.1 - 1.7 7.7 5.2 3.2 6.8 3.6 1.4 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus zf-CCCH PF00642.19 OAJ27015.1 - 1.9e-07 30.6 25.4 3.7e-05 23.2 1.8 4.5 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Chalcone PF02431.10 OAJ27016.1 - 8.1e-43 146.1 0.0 1.1e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Med31 PF05669.7 OAJ27017.1 - 5.4e-28 96.7 0.0 6.3e-28 96.5 0.0 1.0 1 0 0 1 1 1 1 SOH1 eRF1_1 PF03463.10 OAJ27018.1 - 2.2e-52 176.1 0.0 3.4e-52 175.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 OAJ27018.1 - 5.6e-23 81.7 0.0 8.6e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 OAJ27018.1 - 3.1e-22 78.9 0.0 5.8e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 WD40 PF00400.27 OAJ27019.1 - 4e-43 143.8 14.1 1.3e-08 34.3 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat PFU PF09070.6 OAJ27019.1 - 7.1e-43 145.3 0.1 1.2e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 OAJ27019.1 - 4.5e-36 124.0 0.0 6e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 PUL domain PQQ_3 PF13570.1 OAJ27019.1 - 0.11 12.8 1.8 37 4.7 0.0 4.4 4 0 0 4 4 4 0 PQQ-like domain Chromate_transp PF02417.10 OAJ27020.1 - 4.9e-53 179.1 32.4 9e-30 103.4 6.7 2.7 3 1 0 3 3 3 2 Chromate transporter Sugar_tr PF00083.19 OAJ27021.1 - 1.4e-28 99.6 22.8 1.8e-19 69.6 5.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ27021.1 - 7.1e-14 51.2 43.5 6.5e-09 34.9 15.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FBPase PF00316.15 OAJ27024.1 - 5.9e-129 429.5 0.0 6.4e-129 429.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 OAJ27024.1 - 0.00082 18.7 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Inositol monophosphatase family Atx10homo_assoc PF09759.4 OAJ27025.1 - 6.7e-17 61.1 0.0 9.3e-16 57.4 0.0 2.7 2 1 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Neuropeptide_S PF14993.1 OAJ27025.1 - 0.074 12.7 0.1 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Neuropeptide S precursor protein Synthase_beta PF11421.3 OAJ27025.1 - 0.075 13.7 0.2 0.075 13.7 0.1 3.5 3 0 0 3 3 3 0 ATP synthase F1 beta subunit BAR PF03114.13 OAJ27026.1 - 2.7e-50 171.0 2.1 3.2e-50 170.8 1.5 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 OAJ27026.1 - 5.9e-05 22.5 1.4 7.2e-05 22.2 1.0 1.1 1 0 0 1 1 1 1 Arfaptin-like domain AAA_13 PF13166.1 OAJ27026.1 - 0.057 11.8 1.5 0.07 11.5 1.1 1.2 1 0 0 1 1 1 0 AAA domain Ifi-6-16 PF06140.8 OAJ27027.1 - 8e-05 22.3 10.7 0.00012 21.8 7.4 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF1576 PF07613.6 OAJ27027.1 - 0.051 13.0 7.9 0.069 12.6 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) AAA PF00004.24 OAJ27028.1 - 5.4e-32 110.7 0.0 1.2e-31 109.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ27028.1 - 3.3e-08 33.7 0.0 1.2e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ27028.1 - 8e-08 32.4 0.1 4.2e-07 30.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 OAJ27028.1 - 1.4e-06 27.8 0.2 0.038 13.4 0.0 2.7 2 1 1 3 3 2 2 AAA domain AAA_17 PF13207.1 OAJ27028.1 - 2e-06 28.6 0.0 4.6e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 OAJ27028.1 - 4.7e-06 26.6 0.0 1.3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 OAJ27028.1 - 4.7e-06 26.5 0.0 2e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 OAJ27028.1 - 1e-05 25.3 0.3 0.00076 19.2 0.2 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 OAJ27028.1 - 2.4e-05 24.6 0.0 4.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ27028.1 - 7.6e-05 22.3 0.0 0.00028 20.5 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_24 PF13479.1 OAJ27028.1 - 0.0001 21.9 0.0 0.00028 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 OAJ27028.1 - 0.00032 20.6 0.0 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 OAJ27028.1 - 0.00035 20.2 0.2 0.0027 17.3 0.1 2.2 1 1 0 1 1 1 1 NACHT domain PhoH PF02562.11 OAJ27028.1 - 0.00064 19.0 0.0 0.21 10.8 0.0 3.2 3 0 0 3 3 3 1 PhoH-like protein UPF0079 PF02367.12 OAJ27028.1 - 0.00091 18.8 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 OAJ27028.1 - 0.0016 18.1 0.3 0.0078 15.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 OAJ27028.1 - 0.0026 17.5 0.1 0.0063 16.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 OAJ27028.1 - 0.003 17.7 0.0 0.0069 16.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 OAJ27028.1 - 0.0032 16.9 0.0 0.0079 15.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 OAJ27028.1 - 0.0039 17.1 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAJ27028.1 - 0.0042 16.1 0.0 0.0079 15.2 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 OAJ27028.1 - 0.0044 16.5 0.0 0.0087 15.6 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 OAJ27028.1 - 0.0051 15.9 0.0 0.01 14.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin KAP_NTPase PF07693.9 OAJ27028.1 - 0.0051 15.8 0.0 0.87 8.5 0.0 2.3 1 1 1 2 2 2 1 KAP family P-loop domain DUF815 PF05673.8 OAJ27028.1 - 0.0058 15.5 0.0 0.041 12.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF2075 PF09848.4 OAJ27028.1 - 0.0063 15.5 0.0 0.0095 14.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 OAJ27028.1 - 0.0069 15.9 0.1 0.045 13.3 0.0 2.3 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.8 OAJ27028.1 - 0.017 13.8 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_3 PF07726.6 OAJ27028.1 - 0.025 14.1 0.1 0.27 10.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 OAJ27028.1 - 0.029 13.5 0.0 0.15 11.1 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 OAJ27028.1 - 0.031 14.5 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 OAJ27028.1 - 0.035 14.4 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 OAJ27028.1 - 0.059 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.1 OAJ27028.1 - 0.069 11.5 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain RdRP PF05183.7 OAJ27029.1 - 8.6e-148 493.5 0.0 1.2e-147 493.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RNase_T PF00929.19 OAJ27030.1 - 8.6e-08 32.6 0.0 1e-07 32.4 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF4363 PF14276.1 OAJ27030.1 - 0.024 14.3 0.2 0.037 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) RNase_T PF00929.19 OAJ27031.1 - 2.1e-10 41.1 0.1 2.6e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 Exonuclease PAS_9 PF13426.1 OAJ27031.1 - 0.024 15.0 0.0 0.036 14.4 0.0 1.2 1 0 0 1 1 1 0 PAS domain Telomere_reg-2 PF10193.4 OAJ27032.1 - 1.7e-25 89.4 0.0 4.1e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein MCM PF00493.18 OAJ27033.1 - 1.1e-142 474.8 0.2 1.3e-142 474.4 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 OAJ27033.1 - 1.5e-16 61.0 0.0 4e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 OAJ27033.1 - 1.8e-06 27.2 0.0 0.00045 19.4 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 OAJ27033.1 - 7.3e-06 25.7 0.0 1.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 OAJ27033.1 - 0.00018 21.1 0.0 0.0025 17.4 0.0 2.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAJ27033.1 - 0.023 14.1 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 OAJ27033.1 - 0.041 14.2 0.3 0.15 12.4 0.2 2.1 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 OAJ27033.1 - 0.09 12.9 0.2 0.53 10.4 0.0 2.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L28e PF01778.12 OAJ27034.1 - 8.7e-28 97.0 0.5 1.5e-27 96.3 0.4 1.3 1 0 0 1 1 1 1 Ribosomal L28e protein family Glyco_hydro_108 PF05838.7 OAJ27034.1 - 0.13 12.4 0.1 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 108 Sec1 PF00995.18 OAJ27035.1 - 2.5e-94 316.9 0.0 2.6e-93 313.5 0.0 2.4 1 1 0 1 1 1 1 Sec1 family CBFD_NFYB_HMF PF00808.18 OAJ27036.1 - 1e-20 73.5 0.1 1.8e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAJ27036.1 - 9.9e-06 25.5 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF2613 PF11021.3 OAJ27036.1 - 0.098 12.3 1.4 0.19 11.4 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) PBP1_TM PF14812.1 OAJ27036.1 - 5.1 7.4 10.0 9.2 6.6 6.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Prefoldin PF02996.12 OAJ27037.1 - 3.5e-30 104.1 0.0 4.6e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Syntaxin-6_N PF09177.6 OAJ27037.1 - 0.024 15.0 2.1 0.78 10.1 0.1 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Rabaptin PF03528.10 OAJ27037.1 - 0.046 13.6 1.6 0.061 13.2 0.4 1.7 2 0 0 2 2 2 0 Rabaptin Cortex-I_coil PF09304.5 OAJ27037.1 - 0.35 10.9 5.0 2.9 7.9 0.3 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil Bestrophin PF01062.16 OAJ27038.1 - 2.7e-38 131.6 1.5 9.6e-37 126.5 1.0 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel ATP_Ca_trans_C PF12424.3 OAJ27040.1 - 0.037 14.3 2.0 0.086 13.2 0.1 2.7 2 0 0 2 2 2 0 Plasma membrane calcium transporter ATPase C terminal LRR19-TM PF15176.1 OAJ27040.1 - 1.5 8.5 5.3 0.9 9.2 0.2 3.1 3 1 0 3 3 3 0 Leucine-rich repeat family 19 TM domain UCH PF00443.24 OAJ27041.1 - 2.2e-70 236.8 0.0 3.9e-70 236.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ27041.1 - 1.1e-26 93.9 0.0 3.4e-26 92.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 OAJ27041.1 - 3.3e-07 30.2 0.8 8.3e-07 28.9 0.5 1.7 1 1 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.15 OAJ27041.1 - 7.9e-05 22.9 0.0 0.00097 19.4 0.0 2.6 2 0 0 2 2 2 1 Rhodanese-like domain MIT PF04212.13 OAJ27041.1 - 0.058 13.2 0.7 0.12 12.3 0.5 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DUF104 PF01954.11 OAJ27041.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF104 Paramyxo_PNT PF13825.1 OAJ27041.1 - 0.67 9.0 7.3 2 7.5 0.4 2.3 2 0 0 2 2 2 0 Paramyxovirus structural protein V/P N-terminus Fibrillarin PF01269.12 OAJ27042.1 - 2.3e-107 357.1 0.0 2.9e-107 356.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 OAJ27042.1 - 4e-05 23.2 0.0 5.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 OAJ27042.1 - 0.0023 17.5 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 OAJ27042.1 - 0.0092 15.5 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RRM_1 PF00076.17 OAJ27043.1 - 6.9e-18 64.0 0.0 1.1e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ27043.1 - 2.5e-15 56.1 0.2 7.2e-15 54.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ27043.1 - 6.4e-08 32.3 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2763 PF10961.3 OAJ27043.1 - 6.5 7.2 13.7 0.74 10.2 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) DUF2407 PF10302.4 OAJ27044.1 - 1e-12 48.0 0.6 2.5e-11 43.6 0.4 2.8 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2407_C PF13373.1 OAJ27044.1 - 1.3e-10 41.3 4.7 2.8e-09 37.0 1.4 3.1 2 1 0 2 2 2 1 DUF2407 C-terminal domain ubiquitin PF00240.18 OAJ27044.1 - 0.0052 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF1769 PF08588.5 OAJ27045.1 - 5e-17 61.5 0.2 8.5e-17 60.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DUF59 PF01883.14 OAJ27046.1 - 3e-09 36.7 0.0 5.5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 Fungal_trans PF04082.13 OAJ27047.1 - 1.1e-28 99.8 0.0 2e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ27047.1 - 8.5e-10 38.3 6.5 1.5e-09 37.5 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2_5_RNA_ligase2 PF13563.1 OAJ27048.1 - 0.12 12.0 0.7 0.13 11.9 0.5 1.0 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily DUF1708 PF08101.6 OAJ27052.1 - 1.1e-13 50.8 1.2 1.2e-09 37.5 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF1708) RhoGAP PF00620.22 OAJ27052.1 - 0.0086 15.6 0.0 2.6 7.6 0.0 2.4 2 0 0 2 2 2 2 RhoGAP domain CDC45 PF02724.9 OAJ27053.1 - 1.6e-182 607.8 0.0 1.7e-135 452.5 0.0 2.1 1 1 1 2 2 2 2 CDC45-like protein Cas_Csy4 PF09618.5 OAJ27053.1 - 0.065 13.0 0.0 0.68 9.7 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) FAD_binding_7 PF03441.9 OAJ27068.1 - 7.9e-90 300.8 0.0 1.2e-89 300.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 OAJ27068.1 - 9.5e-39 132.7 0.0 1.5e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase p450 PF00067.17 OAJ27069.1 - 1.1e-67 228.5 0.0 3.9e-53 180.6 0.0 1.9 2 0 0 2 2 2 2 Cytochrome P450 Ribosomal_L13 PF00572.13 OAJ27070.1 - 1.9e-24 86.1 0.0 3.2e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 Kua-UEV1_localn PF10520.4 OAJ27070.1 - 0.11 12.1 0.3 0.15 11.6 0.2 1.2 1 0 0 1 1 1 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain Ribosomal_L32e PF01655.13 OAJ27071.1 - 1.2e-45 154.0 2.0 1.4e-45 153.8 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 DUF1771 PF08590.5 OAJ27072.1 - 2e-21 75.7 8.7 4.9e-21 74.5 6.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 OAJ27072.1 - 7.1e-17 61.3 0.2 2.2e-16 59.8 0.1 1.9 1 0 0 1 1 1 1 Smr domain PAT1 PF09770.4 OAJ27072.1 - 2.5 6.2 15.2 3.3 5.8 10.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 OAJ27072.1 - 9.3 4.3 26.0 11 4.0 18.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RNB PF00773.14 OAJ27076.1 - 5.2e-54 183.7 0.0 7.5e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 RNB domain DUF1708 PF08101.6 OAJ27077.1 - 3.3e-22 78.8 0.2 1e-16 60.8 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF1708) RhoGAP PF00620.22 OAJ27077.1 - 0.00025 20.6 0.0 0.00083 18.9 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain eIF-3c_N PF05470.7 OAJ27077.1 - 6.3 4.7 1.9 12 3.8 1.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Zn_clus PF00172.13 OAJ27078.1 - 0.00015 21.5 11.4 0.00026 20.8 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 OAJ27078.1 - 0.00084 18.3 25.2 0.00084 18.3 17.5 4.1 3 1 1 4 4 4 1 BAF1 / ABF1 chromatin reorganising factor Suf PF05843.9 OAJ27078.1 - 2.2 7.9 19.4 4.6 6.8 8.5 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SPX PF03105.14 OAJ27078.1 - 3.6 7.2 11.6 13 5.4 4.7 2.3 2 0 0 2 2 2 0 SPX domain Dus PF01207.12 OAJ27079.1 - 3.8e-44 150.7 0.0 2.2e-24 85.8 0.0 3.1 3 0 0 3 3 3 3 Dihydrouridine synthase (Dus) DUF3752 PF12572.3 OAJ27079.1 - 0.015 15.3 0.3 0.026 14.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Mito_carr PF00153.22 OAJ27080.1 - 4e-72 238.0 1.5 2.2e-26 91.3 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2457 PF10446.4 OAJ27080.1 - 0.037 12.7 1.1 0.057 12.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 OAJ27080.1 - 3.8 5.3 5.5 5.1 4.8 3.8 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L14 PF00238.14 OAJ27081.1 - 6.6e-42 142.1 0.7 7.8e-42 141.8 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pkinase PF00069.20 OAJ27082.1 - 8.5e-72 241.4 0.1 4.5e-65 219.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ27082.1 - 1.9e-36 125.4 0.1 2.4e-33 115.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.14 OAJ27082.1 - 3.3e-18 64.8 0.4 5.8e-18 64.0 0.3 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 OAJ27082.1 - 3.1e-05 23.1 0.0 5.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ27082.1 - 0.00029 20.6 0.9 0.015 15.0 0.0 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ27082.1 - 0.0098 14.8 0.0 0.023 13.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like WaaY PF06176.6 OAJ27082.1 - 0.16 11.1 0.3 0.25 10.5 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) SET PF00856.23 OAJ27083.1 - 2.1e-09 37.8 0.0 2.1e-09 37.8 0.0 3.4 4 2 0 4 4 4 1 SET domain Cytochrom_NNT PF03264.9 OAJ27083.1 - 0.066 12.6 3.3 0.13 11.6 2.3 1.4 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Pkinase PF00069.20 OAJ27084.1 - 2.2e-60 203.9 0.0 2.8e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ27084.1 - 8.8e-34 116.7 0.0 1.2e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ27084.1 - 1.3e-06 27.6 0.0 2.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ27084.1 - 0.031 14.0 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ27084.1 - 0.077 11.8 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 OAJ27084.1 - 0.092 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 OAJ27084.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1777 PF08648.7 OAJ27085.1 - 5.4e-20 71.8 31.3 5.4e-20 71.8 21.7 3.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) MARVEL PF01284.18 OAJ27088.1 - 7.9e-06 25.7 9.8 1.3e-05 25.0 6.8 1.4 1 1 0 1 1 1 1 Membrane-associating domain Zip PF02535.17 OAJ27088.1 - 0.0001 21.4 0.0 0.00012 21.1 0.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter zf-C2H2_4 PF13894.1 OAJ27089.1 - 0.086 13.2 8.7 1.6 9.2 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C4H2 PF10146.4 OAJ27089.1 - 0.15 12.0 2.7 0.39 10.6 1.9 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein HEAT PF02985.17 OAJ27090.1 - 9.1e-37 121.8 24.2 0.0024 17.7 0.1 13.6 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.1 OAJ27090.1 - 5.9e-32 109.8 5.8 1.8e-08 34.5 0.0 6.7 2 2 3 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 OAJ27090.1 - 5.3e-10 39.5 0.8 0.081 13.3 0.1 6.7 4 2 6 10 10 10 4 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 OAJ27090.1 - 5.8e-09 36.1 23.9 0.31 11.6 0.0 8.8 8 2 2 10 10 10 5 HEAT-like repeat CLASP_N PF12348.3 OAJ27090.1 - 0.00041 19.7 2.3 0.026 13.9 0.1 4.3 1 1 2 4 4 4 1 CLASP N terminal Adaptin_N PF01602.15 OAJ27090.1 - 0.0019 16.6 7.8 0.055 11.7 0.2 4.2 4 1 1 5 5 5 1 Adaptin N terminal region DUF3554 PF12074.3 OAJ27090.1 - 0.015 14.7 0.1 14 4.9 0.0 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF3554) Arm PF00514.18 OAJ27090.1 - 0.12 12.2 5.3 7 6.6 0.0 5.5 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat DNA_pol_B PF00136.16 OAJ27091.1 - 1.5e-89 300.9 0.0 2.1e-89 300.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 OAJ27091.1 - 3.9e-22 78.5 0.0 3.3e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 OAJ27091.1 - 5.3e-11 42.3 6.7 1e-10 41.4 4.6 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF515 PF04415.7 OAJ27092.1 - 0.41 8.8 12.6 0.49 8.5 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DNA_pol_viral_N PF00242.12 OAJ27092.1 - 7.2 5.5 6.6 8.1 5.3 4.6 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Aldedh PF00171.17 OAJ27093.1 - 3e-129 431.3 0.0 3.6e-129 431.1 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family S-methyl_trans PF02574.11 OAJ27094.1 - 8.5e-35 120.5 0.0 1.7e-33 116.2 0.0 2.5 1 1 0 1 1 1 1 Homocysteine S-methyltransferase DUF4107 PF13389.1 OAJ27094.1 - 0.032 13.9 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) DnaJ PF00226.26 OAJ27095.1 - 1.4e-20 72.7 0.5 2.5e-20 71.9 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Gly-zipper_OmpA PF13436.1 OAJ27095.1 - 0.045 13.4 0.4 0.094 12.3 0.3 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 OAJ27095.1 - 2.1 8.5 9.8 0.59 10.3 4.3 1.8 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.1 OAJ27095.1 - 5.8 6.5 9.8 41 3.7 6.8 2.2 1 1 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 OAJ27095.1 - 7.2 6.3 9.5 5.1 6.8 2.4 2.5 1 1 2 3 3 3 0 Glycine zipper 2TM domain Vps39_1 PF10366.4 OAJ27096.1 - 3e-28 97.9 1.0 6.2e-28 96.9 0.2 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 OAJ27096.1 - 6.8e-20 71.2 0.2 2.1e-19 69.6 0.1 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 OAJ27096.1 - 4.2e-15 55.9 0.0 8.1e-06 25.4 0.0 3.3 3 0 0 3 3 3 3 CNH domain Clathrin PF00637.15 OAJ27096.1 - 3.6e-09 36.3 3.5 1.3e-05 24.8 0.1 2.9 3 0 0 3 3 3 2 Region in Clathrin and VPS Apc3 PF12895.2 OAJ27096.1 - 0.022 14.8 0.7 0.18 11.9 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 OAJ27096.1 - 0.26 11.3 0.3 23 5.2 0.1 3.3 3 0 0 3 3 3 0 PPR repeat TPR_1 PF00515.23 OAJ27096.1 - 0.36 10.5 4.2 1.8 8.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat CENP-T PF15511.1 OAJ27097.1 - 0.083 12.1 7.1 0.1 11.8 4.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Trypan_PARP PF05887.6 OAJ27097.1 - 0.09 12.5 6.3 0.14 12.0 4.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Glypican PF01153.14 OAJ27097.1 - 0.43 9.1 1.6 0.54 8.8 1.1 1.1 1 0 0 1 1 1 0 Glypican DUF2201_N PF13203.1 OAJ27097.1 - 0.59 9.2 4.3 0.82 8.7 3.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Sporozoite_P67 PF05642.6 OAJ27097.1 - 2.9 5.6 12.1 4.1 5.1 8.4 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen EamA PF00892.15 OAJ27098.1 - 9.4e-05 22.4 6.2 9.4e-05 22.4 4.3 2.7 3 1 0 3 3 3 1 EamA-like transporter family DUF1003 PF06210.6 OAJ27098.1 - 0.0049 16.7 0.2 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1003) zf-CCHC PF00098.18 OAJ27099.1 - 4.8e-15 54.6 16.8 0.00062 19.5 0.4 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ27099.1 - 6.6e-08 32.0 16.1 0.015 14.9 0.3 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ27099.1 - 1.3e-06 27.7 10.3 0.033 13.6 0.1 4.5 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ27099.1 - 0.66 9.7 6.3 12 5.6 0.5 3.7 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_5 PF14787.1 OAJ27099.1 - 3.1 7.3 13.0 13 5.3 0.0 4.3 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger EPSP_synthase PF00275.15 OAJ27100.1 - 9.6e-107 356.9 0.0 1.4e-106 356.4 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 OAJ27100.1 - 1.1e-95 319.4 0.0 3.5e-95 317.8 0.0 1.8 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 OAJ27100.1 - 1.1e-48 165.8 0.0 1.9e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 OAJ27100.1 - 5.9e-23 80.7 0.0 2.4e-22 78.7 0.0 2.1 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 OAJ27100.1 - 1.1e-21 77.3 0.0 2.6e-20 72.8 0.0 2.9 3 1 0 3 3 3 1 Shikimate kinase Shikimate_DH PF01488.15 OAJ27100.1 - 1.7e-10 41.0 0.0 3.9e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 OAJ27100.1 - 1.2e-05 24.7 0.0 3e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF1295 PF06966.7 OAJ27101.1 - 8.5e-41 139.7 0.8 1.5e-40 138.9 0.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 OAJ27101.1 - 0.00033 20.4 1.7 0.00073 19.3 0.1 2.1 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 OAJ27101.1 - 0.0011 18.9 0.0 0.0011 18.9 0.0 2.6 3 1 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.9 OAJ27101.1 - 0.012 15.8 0.0 0.034 14.3 0.0 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family His_Phos_2 PF00328.17 OAJ27102.1 - 6e-27 94.8 0.0 1.6e-26 93.4 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) YtpI PF14007.1 OAJ27102.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 YtpI-like protein Peptidase_S8 PF00082.17 OAJ27103.1 - 0.43 9.6 5.7 0.54 9.3 3.9 1.1 1 0 0 1 1 1 0 Subtilase family Peptidase_C13 PF01650.13 OAJ27104.1 - 2.5e-43 148.2 0.4 3.6e-43 147.7 0.3 1.2 1 0 0 1 1 1 1 Peptidase C13 family DUF2404 PF10296.4 OAJ27106.1 - 1.4e-07 31.5 0.0 2.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) adh_short PF00106.20 OAJ27107.1 - 2.1e-22 79.8 0.5 5.9e-22 78.3 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ27107.1 - 2e-17 63.7 0.1 2.5e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ27107.1 - 3e-07 30.2 0.1 6.7e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 OAJ27107.1 - 0.32 10.8 4.0 6.4 6.6 0.2 2.9 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Vps55 PF04133.9 OAJ27109.1 - 2.2e-44 150.0 4.7 2.5e-44 149.8 3.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 FtsX PF02687.16 OAJ27109.1 - 5 6.9 10.4 1.5 8.6 4.3 2.1 1 1 1 2 2 2 0 FtsX-like permease family zf-RING_4 PF14570.1 OAJ27110.1 - 6.1e-21 73.7 11.5 9.8e-21 73.0 8.0 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 OAJ27110.1 - 1.2e-05 24.8 8.2 2e-05 24.1 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ27110.1 - 0.017 15.1 12.1 0.028 14.4 8.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 OAJ27110.1 - 0.022 14.6 0.0 0.12 12.2 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.1 OAJ27110.1 - 0.026 14.2 3.4 0.062 13.0 2.4 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger RRM_1 PF00076.17 OAJ27110.1 - 0.053 13.1 0.0 0.26 10.9 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 OAJ27110.1 - 1.2 8.8 7.9 1 9.0 4.3 1.7 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) His_Phos_1 PF00300.17 OAJ27111.1 - 1.1e-16 61.3 0.0 1.4e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 OAJ27111.1 - 0.015 14.6 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) DUF2828 PF11443.3 OAJ27112.1 - 3.6e-144 480.8 0.0 4.2e-144 480.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Asp PF00026.18 OAJ27113.1 - 1.7e-27 96.5 0.0 5.8e-27 94.7 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ27113.1 - 0.0024 17.8 0.5 0.0052 16.7 0.1 1.7 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 OAJ27113.1 - 0.039 13.7 0.1 1.2 8.9 0.0 2.9 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAJ27113.1 - 0.05 14.1 0.0 2.8 8.5 0.0 3.0 2 1 0 2 2 2 0 Aspartyl protease Ras PF00071.17 OAJ27114.1 - 4.7e-58 195.1 0.0 5.4e-58 194.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ27114.1 - 3.6e-16 59.7 0.0 5e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ27114.1 - 9.8e-07 28.1 0.0 1.8e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ27114.1 - 0.00043 19.7 0.0 0.0019 17.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 OAJ27114.1 - 0.0038 16.4 0.0 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 OAJ27114.1 - 0.011 14.8 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 OAJ27114.1 - 0.13 11.7 0.0 11 5.5 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AMP-binding PF00501.23 OAJ27115.1 - 6.6e-35 120.3 0.2 1.9e-34 118.8 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 OAJ27115.1 - 4.1e-26 91.4 0.0 7.4e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 OAJ27115.1 - 3.8e-08 33.0 0.0 1.2e-07 31.4 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 OAJ27115.1 - 4.1e-06 26.9 0.0 8.9e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 OAJ27115.1 - 0.0076 14.9 0.0 0.39 9.3 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 OAJ27115.1 - 0.013 15.3 0.4 0.075 12.9 0.1 2.5 2 1 0 2 2 2 0 short chain dehydrogenase zf-4CXXC_R1 PF10497.4 OAJ27115.1 - 0.14 12.3 0.2 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Polysacc_synt_2 PF02719.10 OAJ27115.1 - 0.22 10.4 0.0 5.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Oxidored_molyb PF00174.14 OAJ27122.1 - 1.8e-48 164.1 0.0 3.1e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 OAJ27122.1 - 9.7e-42 141.7 0.1 1.8e-41 140.8 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.19 OAJ27122.1 - 1.2e-23 83.0 0.0 4.4e-23 81.2 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 OAJ27122.1 - 4.2e-21 75.5 0.0 2e-20 73.3 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 OAJ27122.1 - 4.4e-20 71.2 0.0 7.8e-20 70.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 OAJ27122.1 - 0.00037 20.4 0.0 0.0064 16.3 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain MFS_1 PF07690.11 OAJ27123.1 - 4.8e-27 94.6 29.9 9.2e-27 93.6 20.7 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily MutS_V PF00488.16 OAJ27124.1 - 1.7e-70 237.0 0.0 4e-69 232.5 0.0 2.4 1 1 1 2 2 2 1 MutS domain V MutS_III PF05192.13 OAJ27124.1 - 4.2e-44 150.7 0.0 1.6e-43 148.8 0.0 2.0 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.15 OAJ27124.1 - 3.3e-19 68.9 0.0 7.3e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 OAJ27124.1 - 1.5e-08 34.7 1.2 5.1e-08 33.0 0.0 2.6 3 0 0 3 3 3 1 MutS domain II AAA_23 PF13476.1 OAJ27124.1 - 0.34 11.2 3.0 2 8.6 0.0 2.7 2 1 1 3 3 3 0 AAA domain Oxysterol_BP PF01237.13 OAJ27125.1 - 2e-86 289.6 0.0 2.9e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Ras PF00071.17 OAJ27126.1 - 1.4e-50 170.7 0.1 1.7e-50 170.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ27126.1 - 6.7e-17 62.0 0.0 1e-16 61.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ27126.1 - 1.3e-11 44.0 0.0 1.7e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ27126.1 - 0.00036 19.7 0.0 0.00043 19.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 OAJ27126.1 - 0.002 16.8 0.8 0.34 9.5 0.1 2.3 2 1 0 2 2 2 2 G-protein alpha subunit RNA_helicase PF00910.17 OAJ27126.1 - 0.018 15.2 0.3 0.61 10.2 0.2 2.2 1 1 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 OAJ27126.1 - 0.084 13.0 0.3 0.19 11.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 OAJ27126.1 - 0.091 12.0 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein SRPRB PF09439.5 OAJ27126.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 OAJ27126.1 - 0.15 11.0 0.4 0.27 10.2 0.1 1.5 2 0 0 2 2 2 0 Septin Thioredoxin PF00085.15 OAJ27127.1 - 4.9e-23 80.7 0.0 6e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 OAJ27127.1 - 7.6e-08 32.5 0.0 1.2e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAJ27127.1 - 8.9e-06 25.7 0.0 0.00031 20.8 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like HyaE PF07449.6 OAJ27127.1 - 0.00058 19.7 0.0 0.00082 19.2 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE KaiB PF07689.7 OAJ27127.1 - 0.00072 18.9 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 KaiB domain Thioredoxin_7 PF13899.1 OAJ27127.1 - 0.00082 19.3 0.0 0.0015 18.5 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 OAJ27127.1 - 0.0011 18.6 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.9 OAJ27127.1 - 0.0029 17.8 0.0 0.0043 17.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_9 PF14595.1 OAJ27127.1 - 0.0034 16.9 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 OAJ27127.1 - 0.0051 16.4 0.0 0.0065 16.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.11 OAJ27127.1 - 0.0057 16.1 0.0 0.0071 15.8 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Redoxin PF08534.5 OAJ27127.1 - 0.0097 15.4 0.0 0.014 14.9 0.0 1.4 1 1 0 1 1 1 1 Redoxin DUF953 PF06110.6 OAJ27127.1 - 0.0098 15.3 0.1 0.042 13.2 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) TraF PF13728.1 OAJ27127.1 - 0.012 15.1 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Glutaredoxin PF00462.19 OAJ27127.1 - 0.018 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin DUF3505 PF12013.3 OAJ27128.1 - 7e-05 23.0 3.6 0.00087 19.5 2.4 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3505) Nic96 PF04097.9 OAJ27129.1 - 1.1e-164 548.9 0.0 1.4e-164 548.6 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Voltage_CLC PF00654.15 OAJ27130.1 - 8.2e-92 307.9 29.6 1.5e-91 307.0 20.5 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 OAJ27130.1 - 9.4e-13 47.7 0.1 2.3e-06 27.2 0.1 2.6 2 0 0 2 2 2 2 CBS domain EMP24_GP25L PF01105.19 OAJ27131.1 - 1.2e-51 174.9 0.0 1.5e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NIR_SIR PF01077.17 OAJ27132.1 - 3.2e-29 101.3 0.0 6.1e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 OAJ27132.1 - 2.1e-25 89.8 0.2 5.2e-25 88.5 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ27132.1 - 1.1e-16 61.0 6.7 1.6e-13 50.8 0.5 3.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 OAJ27132.1 - 3.6e-16 58.7 0.0 1.1e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.10 OAJ27132.1 - 2.2e-13 50.0 2.9 4e-11 42.7 3.1 2.6 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.12 OAJ27132.1 - 7.3e-13 47.9 0.0 1.5e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.21 OAJ27132.1 - 4.4e-11 42.2 0.0 1.6e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 OAJ27132.1 - 1e-07 32.2 1.1 0.0028 17.7 0.1 4.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ27132.1 - 0.00017 20.5 3.6 0.025 13.4 0.1 4.2 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ27132.1 - 0.0003 19.7 4.6 0.08 11.7 0.1 3.2 1 1 1 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 OAJ27132.1 - 0.00097 18.9 3.2 5 6.8 0.0 3.7 3 1 1 4 4 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 OAJ27132.1 - 0.0029 16.5 0.0 0.73 8.6 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 OAJ27132.1 - 0.012 15.8 1.7 2.7 8.3 0.0 3.1 3 0 0 3 3 3 0 Putative NAD(P)-binding TrkA_N PF02254.13 OAJ27132.1 - 0.018 15.0 1.9 1.6 8.7 0.2 2.9 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.15 OAJ27132.1 - 0.035 14.2 1.1 4.6 7.3 0.0 3.6 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase PAC2 PF09754.4 OAJ27133.1 - 4.2e-25 88.8 0.0 8.3e-25 87.9 0.0 1.5 1 1 0 1 1 1 1 PAC2 family Aminotran_1_2 PF00155.16 OAJ27134.1 - 2.9e-33 115.2 0.0 3.5e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAJ27134.1 - 0.063 12.4 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase bZIP_1 PF00170.16 OAJ27135.1 - 0.00066 19.5 7.5 0.00066 19.5 5.2 2.4 1 1 1 2 2 2 1 bZIP transcription factor CD20 PF04103.10 OAJ27135.1 - 0.07 13.0 1.1 0.12 12.3 0.7 1.3 1 0 0 1 1 1 0 CD20-like family Serinc PF03348.10 OAJ27135.1 - 2 7.0 6.6 3 6.4 4.6 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Zip PF02535.17 OAJ27135.1 - 2.2 7.2 9.5 3.9 6.3 6.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2217 PF10265.4 OAJ27135.1 - 3.6 6.2 9.0 0.075 11.7 1.3 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) UPF0560 PF10577.4 OAJ27135.1 - 5.5 5.1 15.1 10 4.2 10.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2512 PF10710.4 OAJ27135.1 - 6.6 6.2 5.7 9.8 5.6 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) Ribosomal_L5_C PF00673.16 OAJ27136.1 - 4.1e-05 23.2 0.0 0.00014 21.5 0.0 1.8 1 1 0 1 1 1 1 ribosomal L5P family C-terminus DUF543 PF04418.7 OAJ27136.1 - 0.059 13.3 0.5 0.16 11.9 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF543) PhoD PF09423.5 OAJ27138.1 - 2.2e-43 148.4 0.1 7.4e-43 146.7 0.1 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase Cyclin PF08613.6 OAJ27140.1 - 3.1e-13 50.3 0.0 6.1e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 OAJ27140.1 - 4.2e-05 23.1 0.0 7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF466 PF04328.8 OAJ27140.1 - 0.055 13.2 4.0 0.16 11.8 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF466) CBF PF03914.12 OAJ27140.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 CBF/Mak21 family Parvo_coat PF00740.13 OAJ27141.1 - 9.1 5.1 10.6 12 4.7 7.3 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 14-3-3 PF00244.15 OAJ27142.1 - 1.1e-118 394.5 5.3 1.2e-118 394.3 3.7 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 OAJ27142.1 - 0.009 15.5 3.7 1 8.8 0.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF837) HisKA PF00512.20 OAJ27142.1 - 0.16 11.9 2.2 2.5 8.1 0.1 2.8 2 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Adaptin_N PF01602.15 OAJ27143.1 - 6.9e-125 417.3 8.8 8.4e-125 417.0 6.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 OAJ27143.1 - 2.4e-40 137.0 0.0 7.7e-40 135.3 0.0 1.9 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 OAJ27143.1 - 5.3e-19 68.6 0.0 2.7e-18 66.3 0.0 2.1 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT PF02985.17 OAJ27143.1 - 8 6.8 6.9 8.2 6.8 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat SAGA-Tad1 PF12767.2 OAJ27144.1 - 2e-47 161.9 0.0 3.4e-47 161.2 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit DUF4637 PF15470.1 OAJ27144.1 - 1.7 8.2 7.9 0.08 12.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) BRF1 PF07741.8 OAJ27144.1 - 5.3 7.3 10.6 1.9 8.7 1.8 2.9 3 0 0 3 3 3 0 Brf1-like TBP-binding domain WD40 PF00400.27 OAJ27145.1 - 6.5e-07 28.9 7.2 1.5e-05 24.6 0.2 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF2415 PF10313.4 OAJ27145.1 - 0.035 13.7 0.0 14 5.4 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) zf-HC5HC2H_2 PF13832.1 OAJ27146.1 - 1.3e-19 70.2 2.1 1.3e-19 70.2 1.4 4.5 4 1 0 4 4 4 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 OAJ27146.1 - 1.6e-16 60.1 2.0 1.6e-16 60.1 1.4 4.6 5 0 0 5 5 5 2 PHD-like zinc-binding domain PHD PF00628.24 OAJ27146.1 - 6.3e-15 54.6 46.4 2.6e-09 36.6 4.1 5.2 6 0 0 6 6 6 3 PHD-finger BAH PF01426.13 OAJ27146.1 - 1e-08 34.9 0.0 2.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 BAH domain GATA PF00320.22 OAJ27146.1 - 6.7e-07 28.5 4.1 6.7e-07 28.5 2.9 4.3 5 0 0 5 5 5 1 GATA zinc finger PHD_2 PF13831.1 OAJ27146.1 - 5e-05 22.5 2.8 5e-05 22.5 1.9 5.7 6 0 0 6 6 6 2 PHD-finger ELM2 PF01448.19 OAJ27146.1 - 0.11 13.1 0.0 0.32 11.6 0.0 1.8 1 0 0 1 1 1 0 ELM2 domain DUF498 PF04430.9 OAJ27147.1 - 3.9e-25 87.5 0.0 6.1e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) CHCH PF06747.8 OAJ27148.1 - 1.4e-06 28.0 5.6 2.1e-06 27.5 3.9 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 OAJ27148.1 - 0.026 14.5 3.4 0.22 11.5 2.6 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 OAJ27148.1 - 0.11 12.5 1.0 0.16 12.0 0.7 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 OAJ27148.1 - 0.25 11.1 4.9 0.6 9.9 3.4 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 OAJ27148.1 - 0.41 10.5 2.1 3.3 7.6 0.1 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) COX17 PF05051.8 OAJ27148.1 - 0.64 10.0 4.5 2.4 8.2 0.4 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF1770 PF08589.5 OAJ27149.1 - 0.45 11.1 3.5 1.1 9.9 2.4 1.7 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) Transposase_21 PF02992.9 OAJ27150.1 - 6.7e-05 22.0 0.0 0.00014 21.0 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 bZIP_1 PF00170.16 OAJ27152.1 - 1.4e-05 24.9 10.7 1.4e-05 24.9 7.4 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 OAJ27152.1 - 0.0013 18.5 8.9 0.0013 18.5 6.2 2.0 2 0 0 2 2 2 1 Basic region leucine zipper RasGAP PF00616.14 OAJ27153.1 - 9.3e-29 100.4 0.0 2.1e-28 99.3 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 OAJ27153.1 - 7.9e-13 48.5 0.0 3.4e-12 46.5 0.0 2.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.1 OAJ27153.1 - 2.1e-06 27.7 0.1 6e-05 22.9 0.0 2.9 2 0 0 2 2 2 1 Cell morphogenesis C-terminal DUF3253 PF11625.3 OAJ27154.1 - 0.011 15.6 0.0 0.039 13.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) NMO PF03060.10 OAJ27156.1 - 1e-47 162.9 1.3 2.2e-29 102.6 0.1 3.1 2 2 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 OAJ27156.1 - 0.052 12.3 0.1 0.052 12.3 0.0 2.0 3 0 0 3 3 3 0 FMN-dependent dehydrogenase Clat_adaptor_s PF01217.15 OAJ27157.1 - 6e-09 35.7 0.0 8e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain IL6 PF00489.12 OAJ27157.1 - 0.09 12.3 0.2 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family DUF4266 PF14086.1 OAJ27157.1 - 0.13 12.8 8.8 0.63 10.5 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4266) RRM_1 PF00076.17 OAJ27158.1 - 1.3e-72 239.3 0.0 2.1e-18 65.7 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ27158.1 - 3.8e-65 215.7 0.6 1.1e-16 60.5 0.0 6.1 5 1 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ27158.1 - 1e-37 127.7 0.0 1.6e-08 34.2 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 OAJ27158.1 - 0.0017 18.0 4.9 0.13 12.0 0.0 4.9 5 2 1 6 6 6 1 Limkain b1 RRM_2 PF04059.7 OAJ27158.1 - 0.0053 16.7 0.0 6.3 6.8 0.0 3.5 3 0 0 3 3 3 1 RNA recognition motif 2 Nup35_RRM_2 PF14605.1 OAJ27158.1 - 0.14 11.9 0.0 8.6 6.2 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif LIM PF00412.17 OAJ27159.1 - 1.4e-19 69.9 18.4 3.1e-11 43.1 4.5 3.0 2 1 0 2 2 2 2 LIM domain Cytochrom_c3_2 PF14537.1 OAJ27159.1 - 2.1 8.7 12.8 2 8.7 3.7 2.4 2 0 0 2 2 2 0 Cytochrome c3 zf-FPG_IleRS PF06827.9 OAJ27159.1 - 3.6 7.3 0.0 3.6 7.3 0.0 4.9 6 0 0 6 6 6 0 Zinc finger found in FPG and IleRS RhoGAP PF00620.22 OAJ27160.1 - 3.6e-43 146.7 0.0 6.3e-43 145.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PX PF00787.19 OAJ27160.1 - 4.1e-05 23.3 0.0 8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 PX domain PH PF00169.24 OAJ27160.1 - 0.0011 19.1 0.1 0.0092 16.1 0.1 2.2 1 1 0 1 1 1 1 PH domain RabGAP-TBC PF00566.13 OAJ27161.1 - 4.1e-48 163.6 0.0 6.4e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 OAJ27161.1 - 1.2e-07 31.1 0.0 3.8e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 GRAM domain NUDIX PF00293.23 OAJ27162.1 - 6.9e-09 35.4 0.0 2.3e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain eIF-5a PF01287.15 OAJ27163.1 - 6.7e-28 96.4 1.2 9.5e-28 95.9 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 OAJ27163.1 - 8.4e-05 22.1 0.6 0.0002 20.9 0.4 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 OAJ27163.1 - 0.043 13.7 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Pil1 PF13805.1 OAJ27163.1 - 0.052 12.6 0.0 0.069 12.2 0.0 1.1 1 0 0 1 1 1 0 Eisosome component PIL1 ABC2_membrane PF01061.19 OAJ27164.1 - 5.2e-66 221.7 53.1 2.8e-34 118.1 13.9 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 OAJ27164.1 - 7.9e-37 126.6 0.0 1.1e-18 67.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 OAJ27164.1 - 8.7e-20 70.3 0.0 8.7e-20 70.3 0.0 3.4 3 0 0 3 3 3 1 CDR ABC transporter AAA_25 PF13481.1 OAJ27164.1 - 5.2e-09 35.7 0.2 2.8e-05 23.6 0.1 3.4 3 0 0 3 3 3 2 AAA domain ABC_trans_N PF14510.1 OAJ27164.1 - 4.4e-07 29.8 0.2 1.2e-06 28.5 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_29 PF13555.1 OAJ27164.1 - 1.4e-05 24.5 1.0 0.043 13.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 OAJ27164.1 - 0.00019 20.6 0.3 0.024 13.8 0.1 2.9 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 OAJ27164.1 - 0.0013 18.9 0.7 1.4 9.0 0.1 3.4 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.13 OAJ27164.1 - 0.0019 17.7 0.8 0.39 10.1 0.0 3.2 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_16 PF13191.1 OAJ27164.1 - 0.0049 16.8 4.6 0.27 11.1 1.3 3.1 2 1 0 2 2 2 1 AAA ATPase domain UPF0079 PF02367.12 OAJ27164.1 - 0.005 16.4 4.6 0.89 9.1 0.2 3.2 3 0 0 3 3 3 2 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 OAJ27164.1 - 0.008 16.1 0.0 0.71 9.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ27164.1 - 0.0084 16.9 0.2 0.2 12.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain DUF150 PF02576.12 OAJ27164.1 - 0.016 14.8 0.0 5.4 6.5 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised BCR, YhbC family COG0779 MMR_HSR1 PF01926.18 OAJ27164.1 - 0.025 14.5 0.1 8.1 6.4 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 OAJ27164.1 - 0.027 14.0 2.0 1 8.9 0.1 3.2 3 0 0 3 3 3 0 AAA domain PhnG PF06754.7 OAJ27164.1 - 0.035 13.7 0.1 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG cobW PF02492.14 OAJ27164.1 - 0.096 12.1 3.3 0.11 11.9 0.7 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 OAJ27164.1 - 0.48 10.3 5.2 0.14 12.1 0.4 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 OAJ27164.1 - 3.2 8.0 4.7 2.3 8.5 0.7 2.6 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.1 OAJ27164.1 - 7.6 6.4 6.8 5.8 6.7 0.2 3.4 3 1 1 4 4 3 0 AAA domain DUF732 PF05305.9 OAJ27174.1 - 0.075 13.1 0.5 0.1 12.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF732) DPBB_1 PF03330.13 OAJ27175.1 - 0.0077 16.2 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ27175.1 - 0.022 14.4 0.2 0.038 13.6 0.1 1.4 1 0 0 1 1 1 0 Barwin family DUF3402 PF11882.3 OAJ27177.1 - 1.3e-130 436.1 0.0 4.1e-128 427.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.8 OAJ27177.1 - 1.1e-40 139.2 0.0 7.9e-37 126.6 0.0 2.6 2 1 0 2 2 2 2 N1221-like protein RVT_2 PF07727.9 OAJ27180.1 - 5.3e-88 294.1 0.0 7.3e-88 293.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ27180.1 - 4.9e-18 65.3 0.0 2.3e-17 63.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ27180.1 - 3.9e-06 26.4 0.0 1.4e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain HMG_box PF00505.14 OAJ27181.1 - 1.3e-06 28.5 1.4 2.1e-05 24.6 0.9 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box PF00505.14 OAJ27182.1 - 4.3e-09 36.5 3.6 4.6e-05 23.6 1.2 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ27182.1 - 0.0031 17.8 0.7 0.0077 16.5 0.5 1.6 1 0 0 1 1 1 1 HMG-box domain Fimbrial_K88 PF02432.10 OAJ27182.1 - 0.06 12.7 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Fimbrial, major and minor subunit Proteasome PF00227.21 OAJ27184.1 - 7.8e-33 113.3 0.0 9.2e-33 113.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TPR_11 PF13414.1 OAJ27185.1 - 8.6e-12 44.5 1.1 8.3e-07 28.5 0.0 5.0 4 1 1 5 5 5 2 TPR repeat TPR_17 PF13431.1 OAJ27185.1 - 3.1e-05 23.8 0.5 0.77 10.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ27185.1 - 6.7e-05 23.4 5.6 0.00088 19.8 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ27185.1 - 0.00012 21.6 16.0 0.18 11.8 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ27185.1 - 0.00022 21.0 3.6 0.13 12.2 0.0 5.0 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ27185.1 - 0.0021 17.6 1.0 2.2 8.0 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ27185.1 - 0.011 15.5 8.2 7.3 6.6 0.3 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ27185.1 - 0.02 15.5 0.1 0.02 15.5 0.1 6.7 6 2 2 8 8 8 0 Tetratricopeptide repeat DUF2435 PF10363.4 OAJ27186.1 - 1.2e-24 86.0 0.3 1.5e-23 82.5 0.0 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 OAJ27186.1 - 0.046 13.2 0.0 0.15 11.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) PS_Dcarbxylase PF02666.10 OAJ27188.1 - 4.8e-76 254.5 0.0 6.2e-74 247.6 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.6 OAJ27188.1 - 0.0029 17.1 0.0 0.0081 15.7 0.0 1.7 1 0 0 1 1 1 1 MNLL subunit DUF3309 PF11752.3 OAJ27188.1 - 0.14 11.9 0.8 2.4 7.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) Y_phosphatase2 PF03162.8 OAJ27189.1 - 8e-46 155.4 0.0 1.2e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Pex2_Pex12 PF04757.9 OAJ27189.1 - 5.4e-38 130.6 4.0 9e-38 129.9 2.8 1.4 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Y_phosphatase3 PF13350.1 OAJ27189.1 - 1.3e-05 25.5 0.0 5.6e-05 23.4 0.0 1.9 1 1 1 2 2 2 1 Tyrosine phosphatase family zf-4CXXC_R1 PF10497.4 OAJ27189.1 - 0.031 14.4 2.4 1.1 9.4 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Myc_N PF01056.13 OAJ27189.1 - 0.095 11.8 1.3 4.6 6.3 0.1 2.3 2 0 0 2 2 2 0 Myc amino-terminal region RDD PF06271.7 OAJ27189.1 - 0.1 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 RDD family Kinesin PF00225.18 OAJ27190.1 - 4.3e-109 364.2 0.0 6.2e-109 363.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain DUF2370 PF10176.4 OAJ27190.1 - 0.026 13.8 0.8 0.052 12.8 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Atg14 PF10186.4 OAJ27190.1 - 0.033 13.1 1.6 0.058 12.3 1.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Herpes_UL6 PF01763.11 OAJ27190.1 - 0.26 9.4 1.9 0.43 8.6 1.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Seryl_tRNA_N PF02403.17 OAJ27190.1 - 0.95 9.5 6.6 1.2 9.2 2.5 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DnaJ PF00226.26 OAJ27191.1 - 1.1e-15 57.1 0.3 1.9e-15 56.3 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain JAB PF01398.16 OAJ27192.1 - 1.2e-34 118.4 0.1 2.6e-34 117.3 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 OAJ27192.1 - 4.1e-28 97.7 1.7 1.2e-27 96.3 1.2 1.8 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 OAJ27192.1 - 1e-07 31.4 0.0 1.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain PIG-F PF06699.6 OAJ27194.1 - 3.5e-15 56.4 13.1 4.7e-14 52.7 9.1 2.2 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F Uroplakin_II PF07353.7 OAJ27194.1 - 9.5 5.5 8.9 0.39 10.0 2.0 1.6 2 0 0 2 2 2 0 Uroplakin II Suc_Fer-like PF06999.7 OAJ27195.1 - 9.6e-30 104.3 0.0 1.2e-28 100.7 0.0 2.3 1 1 0 1 1 1 1 Sucrase/ferredoxin-like BAR_2 PF10455.4 OAJ27195.1 - 0.044 12.7 1.2 0.065 12.1 0.8 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking FAD-SLDH PF12318.3 OAJ27195.1 - 0.15 11.7 0.9 0.29 10.8 0.6 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF3552 PF12072.3 OAJ27195.1 - 0.17 11.0 6.3 0.27 10.4 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2347 PF09804.4 OAJ27195.1 - 0.37 10.0 2.3 0.57 9.4 1.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Tau95 PF09734.4 OAJ27196.1 - 1.9e-42 145.6 0.0 4.1e-42 144.5 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Mannosyl_trans2 PF04188.8 OAJ27197.1 - 4.2e-58 197.3 5.5 6.6e-58 196.6 3.8 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) GSAP-16 PF14959.1 OAJ27197.1 - 0.028 14.1 0.4 0.048 13.3 0.3 1.3 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term NAD_binding_7 PF13241.1 OAJ27198.1 - 1.3e-27 96.0 0.0 2.1e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 OAJ27198.1 - 1.8e-21 75.1 0.2 3.2e-21 74.4 0.2 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 OAJ27198.1 - 3.6e-10 38.6 0.1 6.5e-10 37.8 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central DIOX_N PF14226.1 OAJ27200.1 - 1.2e-09 38.7 0.2 2.3e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAJ27200.1 - 1.6e-07 31.4 0.0 5.8e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily RasGEF PF00617.14 OAJ27201.1 - 3e-61 206.4 0.1 5e-61 205.7 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 OAJ27201.1 - 2.1e-24 85.6 0.1 2.1e-24 85.6 0.1 3.1 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_9 PF14604.1 OAJ27201.1 - 1.7e-13 49.9 0.2 3.5e-13 48.9 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ27201.1 - 3.7e-13 48.6 0.1 7.7e-13 47.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ27201.1 - 7.9e-12 44.4 0.1 1.5e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 OAJ27201.1 - 0.0016 18.2 3.5 0.13 12.1 0.2 2.6 2 0 0 2 2 2 2 WW domain PQQ PF01011.16 OAJ27201.1 - 0.02 14.4 0.0 0.076 12.5 0.0 2.0 2 0 0 2 2 2 0 PQQ enzyme repeat TPR_11 PF13414.1 OAJ27202.1 - 6.7e-50 166.6 37.2 4.4e-15 55.0 1.1 6.5 5 1 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 OAJ27202.1 - 2.3e-45 150.4 28.8 1.8e-05 24.1 0.2 10.1 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ27202.1 - 4.5e-31 104.2 34.2 0.0048 16.7 0.1 10.2 11 0 0 11 11 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ27202.1 - 2.5e-22 78.9 29.6 5.4e-07 30.1 0.6 7.2 4 3 3 7 7 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ27202.1 - 7.8e-22 77.0 27.6 1.2e-11 44.3 0.6 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ27202.1 - 4.8e-17 60.4 27.8 0.012 15.3 0.1 9.7 8 2 2 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ27202.1 - 2.5e-16 58.6 18.8 0.032 14.8 0.0 9.8 3 3 6 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ27202.1 - 7e-10 38.3 11.1 0.033 14.3 0.1 7.9 9 1 0 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ27202.1 - 7.9e-08 32.5 24.8 1.6e-05 25.1 0.4 6.1 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ27202.1 - 2.1e-07 30.2 16.8 0.034 13.9 0.0 7.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ27202.1 - 2.3e-05 24.5 18.0 2.1 8.9 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ27202.1 - 2.9e-05 23.8 14.3 0.022 14.6 0.4 5.6 3 2 2 5 5 4 3 Tetratricopeptide repeat Apc3 PF12895.2 OAJ27202.1 - 0.0028 17.7 1.4 0.0028 17.7 1.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 OAJ27202.1 - 0.022 14.6 10.1 1.2 9.1 0.2 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 OAJ27202.1 - 0.029 14.2 3.0 4.4 7.2 0.1 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Exonuc_VII_S PF02609.11 OAJ27202.1 - 0.18 11.5 5.0 2.5 7.9 0.0 4.9 5 0 0 5 5 5 0 Exonuclease VII small subunit XPC-binding PF09280.6 OAJ27202.1 - 0.19 11.2 5.4 0.27 10.7 1.8 2.6 2 0 0 2 2 2 0 XPC-binding domain RNase_PH PF01138.16 OAJ27203.1 - 2.6e-19 69.8 0.0 5.1e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 OAJ27203.1 - 2.1e-05 24.3 0.0 5.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 WD40 PF00400.27 OAJ27204.1 - 5.7e-20 70.3 1.3 0.00011 21.9 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ARHGEF5_35 PF15441.1 OAJ27204.1 - 0.0035 16.2 0.6 0.0049 15.7 0.4 1.1 1 0 0 1 1 1 1 Rho guanine nucleotide exchange factor 5/35 Ribosomal_S13 PF00416.17 OAJ27205.1 - 2.4e-38 130.8 1.0 2.9e-38 130.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.1 OAJ27205.1 - 0.014 15.4 0.1 0.036 14.1 0.0 1.6 1 1 0 1 1 1 0 Helix-hairpin-helix motif FbpA PF05833.6 OAJ27205.1 - 0.02 13.4 0.0 0.022 13.2 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Bromodomain PF00439.20 OAJ27206.1 - 1.1e-17 63.6 0.1 2.9e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Peptidase_M1 PF01433.15 OAJ27206.1 - 8e-09 35.0 0.1 0.00077 18.6 0.0 3.9 3 1 0 4 4 4 3 Peptidase family M1 HEAT_2 PF13646.1 OAJ27206.1 - 1.3e-05 25.3 0.5 0.027 14.7 0.0 3.8 4 0 0 4 4 4 2 HEAT repeats Glyco_hydro_31 PF01055.21 OAJ27207.1 - 1.1e-142 475.9 1.2 1.5e-142 475.5 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 OAJ27207.1 - 1.2e-19 69.9 0.0 3.7e-19 68.3 0.0 1.9 2 0 0 2 2 2 1 Galactose mutarotase-like DUF4006 PF13179.1 OAJ27209.1 - 0.076 12.5 0.6 0.14 11.7 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Arm PF00514.18 OAJ27210.1 - 3.2e-07 29.9 22.0 0.0035 17.1 0.1 9.5 12 0 0 12 12 12 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 OAJ27210.1 - 9.1e-05 22.6 15.2 1.8 8.9 0.0 6.3 6 0 0 6 6 6 3 HEAT repeats HEAT PF02985.17 OAJ27210.1 - 0.00012 21.8 10.1 2 8.6 0.0 7.1 7 0 0 7 7 7 1 HEAT repeat V-ATPase_H_N PF03224.9 OAJ27210.1 - 0.00094 18.3 0.0 3.9 6.4 0.0 3.7 4 0 0 4 4 4 2 V-ATPase subunit H BSP_II PF05432.6 OAJ27210.1 - 0.05 12.8 1.5 0.18 11.0 1.0 1.8 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF732 PF05305.9 OAJ27211.1 - 0.083 12.9 0.2 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF732) EAF PF09816.4 OAJ27212.1 - 2.1e-18 66.2 0.0 4.6e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor NOA36 PF06524.7 OAJ27212.1 - 0.0026 17.0 5.7 0.0026 17.0 3.9 2.5 2 1 0 2 2 2 1 NOA36 protein Nop14 PF04147.7 OAJ27212.1 - 5.6 4.7 54.3 1.1 7.1 18.4 2.1 2 0 0 2 2 2 0 Nop14-like family ATP-synt_ab PF00006.20 OAJ27213.1 - 4.6e-63 212.5 0.0 1.1e-62 211.4 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 OAJ27213.1 - 4.2e-25 87.7 2.4 1.3e-24 86.1 1.7 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 OAJ27213.1 - 9.6e-23 80.8 0.7 1.6e-22 80.1 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Arch_ATPase PF01637.13 OAJ27213.1 - 0.0021 17.7 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 OAJ27213.1 - 0.0055 16.1 0.1 0.012 15.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 OAJ27213.1 - 0.0099 15.0 0.2 0.017 14.2 0.1 1.4 1 0 0 1 1 1 1 KaiC DUF258 PF03193.11 OAJ27213.1 - 0.018 14.2 0.1 0.032 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 OAJ27213.1 - 0.019 14.6 0.4 0.96 9.1 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 OAJ27213.1 - 0.026 14.5 0.5 0.077 12.9 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 OAJ27213.1 - 0.038 14.1 0.0 0.21 11.7 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ27213.1 - 0.038 14.1 0.0 0.15 12.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 OAJ27213.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 OAJ27213.1 - 0.05 12.4 0.1 0.096 11.5 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.1 OAJ27213.1 - 0.074 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAJ27213.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Complex1_LYR PF05347.10 OAJ27214.1 - 1.4e-08 34.3 0.8 2.3e-08 33.6 0.6 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAJ27214.1 - 0.00061 19.9 0.5 0.0012 18.9 0.4 1.5 1 0 0 1 1 1 1 Complex1_LYR-like DEC-1_N PF04625.8 OAJ27214.1 - 0.05 12.2 1.5 0.065 11.9 1.1 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF1180 PF06679.7 OAJ27214.1 - 0.071 12.9 1.1 0.093 12.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PLRV_ORF5 PF01690.12 OAJ27214.1 - 5.4 6.0 11.5 8.3 5.4 7.9 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Neisseria_TspB PF05616.8 OAJ27214.1 - 6.1 5.1 5.8 8.5 4.6 4.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF4505 PF14956.1 OAJ27215.1 - 2e-29 102.5 0.0 3.7e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4505) Rep_fac_C PF08542.6 OAJ27216.1 - 2.3e-18 65.9 0.2 6.1e-18 64.5 0.0 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 OAJ27216.1 - 9.5e-13 48.1 0.0 2.1e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 OAJ27216.1 - 9e-05 22.6 0.2 0.00029 21.0 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ27216.1 - 0.00028 21.0 0.2 0.0017 18.5 0.1 2.3 1 1 1 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 OAJ27216.1 - 0.0039 17.2 0.1 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.7 OAJ27216.1 - 0.0044 16.0 0.3 0.3 10.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 OAJ27216.1 - 0.0059 16.4 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 OAJ27216.1 - 0.0078 15.6 0.1 0.038 13.4 0.0 1.9 1 1 0 2 2 2 1 AAA-like domain Rad17 PF03215.10 OAJ27216.1 - 0.015 14.0 0.0 0.059 12.0 0.0 1.9 1 1 1 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 OAJ27216.1 - 0.015 15.2 1.3 0.25 11.3 0.1 2.9 2 2 0 2 2 2 0 AAA ATPase domain SNF2_N PF00176.18 OAJ27216.1 - 0.03 13.1 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF1254 PF06863.7 OAJ27216.1 - 0.092 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) Rubis-subs-bind PF09273.6 OAJ27217.1 - 1.9e-12 47.2 0.0 4.9e-12 45.8 0.0 1.7 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.23 OAJ27217.1 - 3.4e-12 46.9 0.0 7.1e-11 42.6 0.0 2.3 1 1 0 1 1 1 1 SET domain CENP-B_dimeris PF09026.5 OAJ27217.1 - 0.12 12.5 4.3 0.27 11.5 3.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_viral_C PF00336.13 OAJ27219.1 - 0.026 13.7 0.0 0.057 12.6 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain TFIIA PF03153.8 OAJ27221.1 - 0.02 14.8 18.2 0.028 14.3 12.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAPA-1 PF04795.7 OAJ27221.1 - 0.63 10.7 9.4 0.21 12.3 2.1 2.5 2 0 0 2 2 2 0 PAPA-1-like conserved region TRP PF06011.7 OAJ27222.1 - 1.3e-52 178.8 16.2 2.5e-36 125.1 9.2 2.3 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 OAJ27222.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 ML-like domain NOA36 PF06524.7 OAJ27222.1 - 2.2 7.4 2.0 3.4 6.8 1.4 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 OAJ27222.1 - 2.9 7.3 3.9 5 6.6 2.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin FLO_LFY PF01698.11 OAJ27222.1 - 5.1 5.8 4.5 7.6 5.2 3.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein AA_permease PF00324.16 OAJ27223.1 - 1.8e-123 412.4 37.7 2.2e-123 412.1 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAJ27223.1 - 1.2e-39 136.0 42.5 1.6e-39 135.7 29.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 OAJ27223.1 - 0.22 11.1 1.2 15 5.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2665) DUF4481 PF14800.1 OAJ27223.1 - 3.7 6.3 4.8 6.5 5.5 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) AA_permease PF00324.16 OAJ27224.1 - 2.2e-132 441.7 48.4 2.7e-132 441.5 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAJ27224.1 - 1.2e-38 132.7 51.3 1.5e-38 132.5 35.5 1.1 1 0 0 1 1 1 1 Amino acid permease DnaJ PF00226.26 OAJ27225.1 - 6.8e-23 80.1 0.6 1.1e-22 79.4 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 OAJ27225.1 - 3.7e-21 74.7 0.2 1.5e-19 69.6 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 OAJ27225.1 - 2.1e-14 53.2 19.2 3.5e-14 52.6 13.3 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 OAJ27225.1 - 0.22 11.2 12.0 0.57 9.8 2.6 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Stc1 PF12898.2 OAJ27225.1 - 1.1 9.3 7.8 9.1 6.4 0.4 2.3 2 0 0 2 2 2 0 Stc1 domain FAD_binding_3 PF01494.14 OAJ27227.1 - 9.9e-55 186.0 1.0 8.1e-54 183.0 0.7 2.3 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 OAJ27227.1 - 1.3e-18 67.1 0.0 2.5e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.1 OAJ27227.1 - 2.4e-06 27.4 0.0 6.3e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ27227.1 - 6.8e-05 21.9 0.0 0.00013 21.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 OAJ27227.1 - 0.00021 19.8 0.1 0.00034 19.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 OAJ27227.1 - 0.00022 21.1 0.0 0.00046 20.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAJ27227.1 - 0.00026 20.0 0.2 0.00038 19.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAJ27227.1 - 0.0012 19.0 0.0 0.0029 17.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ27227.1 - 0.0012 17.9 0.0 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 OAJ27227.1 - 0.0023 16.6 0.0 0.0036 15.9 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.19 OAJ27227.1 - 0.0034 16.2 0.5 0.0034 16.2 0.4 1.8 3 1 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.22 OAJ27227.1 - 0.0073 16.6 0.1 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ27227.1 - 0.01 15.6 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding ThiF PF00899.16 OAJ27227.1 - 0.038 13.8 0.3 0.087 12.6 0.2 1.6 1 0 0 1 1 1 0 ThiF family K_oxygenase PF13434.1 OAJ27227.1 - 0.051 12.4 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) ApbA PF02558.11 OAJ27227.1 - 0.095 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 OAJ27227.1 - 0.097 12.6 0.1 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 OAJ27227.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3602 PF12223.3 OAJ27228.1 - 2.2e-12 47.1 26.0 1.1e-05 25.6 0.4 4.7 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Creb_binding PF09030.5 OAJ27228.1 - 0.028 14.6 0.2 0.92 9.7 0.0 2.4 2 0 0 2 2 2 0 Creb binding DUF1509 PF07420.6 OAJ27228.1 - 2.3 7.3 9.5 2.8 7.1 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DUF1776 PF08643.5 OAJ27229.1 - 0.00094 18.4 0.0 0.082 12.0 0.0 2.2 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) LIP PF03583.9 OAJ27230.1 - 1.4e-60 205.0 0.0 1.8e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_3 PF07859.8 OAJ27231.1 - 3.7e-19 69.1 0.0 5.3e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAJ27231.1 - 1.7e-09 36.7 0.0 0.00034 19.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 OAJ27231.1 - 0.0064 16.2 0.0 0.0094 15.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family SOG2 PF10428.4 OAJ27232.1 - 0.97 8.0 8.3 1.4 7.5 5.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein eIF3_subunit PF08597.5 OAJ27232.1 - 1.8 8.0 14.0 0.53 9.8 0.2 2.3 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit Asp PF00026.18 OAJ27233.1 - 9.4e-45 153.2 0.8 2.4e-44 151.8 0.6 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 OAJ27233.1 - 2.5e-05 24.7 0.4 0.014 15.9 0.1 2.6 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 OAJ27233.1 - 7.1e-05 22.8 0.6 0.001 19.0 0.4 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 OAJ27233.1 - 0.0055 16.2 0.0 0.019 14.5 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp PF00026.18 OAJ27234.1 - 5.6e-46 157.2 0.2 1.8e-45 155.5 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 OAJ27234.1 - 1.5e-05 24.6 0.0 3.5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 OAJ27234.1 - 0.0022 17.9 1.2 0.023 14.6 0.8 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal FAM220 PF15487.1 OAJ27235.1 - 0.61 9.3 3.0 0.96 8.7 2.1 1.4 1 0 0 1 1 1 0 FAM220 family TAP_C PF03943.8 OAJ27236.1 - 2.6e-09 36.3 0.0 4.9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 OAJ27236.1 - 3.4e-08 32.9 2.4 6.8e-06 25.5 0.8 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 OAJ27236.1 - 0.015 15.3 0.3 15 6.3 0.1 3.6 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 OAJ27236.1 - 0.034 14.1 0.3 2.1 8.6 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.1 OAJ27236.1 - 0.071 12.8 0.9 0.82 9.4 0.1 2.3 2 0 0 2 2 2 0 Leucine rich repeat DUF2454 PF10521.4 OAJ27237.1 - 5.3e-09 35.4 0.0 2.7e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2454) MAP65_ASE1 PF03999.7 OAJ27238.1 - 1.3e-38 133.0 0.0 1.3e-34 119.8 0.0 2.3 2 0 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) TBPIP PF07106.8 OAJ27238.1 - 0.04 13.4 0.4 0.25 10.8 0.0 2.6 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Apolipoprotein PF01442.13 OAJ27238.1 - 5.7 6.3 16.6 0.68 9.4 7.1 2.7 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain Glyco_transf_22 PF03901.12 OAJ27239.1 - 2.1e-70 237.8 14.9 1.7e-68 231.5 10.2 2.0 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family WW PF00397.21 OAJ27240.1 - 0.00032 20.5 0.3 0.00069 19.4 0.2 1.6 1 0 0 1 1 1 1 WW domain DUF3275 PF11679.3 OAJ27240.1 - 9.8 5.7 7.2 5.2 6.6 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) PAD_porph PF04371.10 OAJ27253.1 - 0.008 15.2 1.0 0.74 8.7 0.1 2.1 1 1 1 2 2 2 2 Porphyromonas-type peptidyl-arginine deiminase ATP-synt_S1 PF05827.7 OAJ27254.1 - 0.029 13.7 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) DEAD PF00270.24 OAJ27255.1 - 4.1e-46 156.5 0.0 7.7e-45 152.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ27255.1 - 5.5e-26 90.2 0.0 1.5e-25 88.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Phage_Gp23 PF10669.4 OAJ27255.1 - 0.047 13.7 0.4 0.047 13.7 0.3 3.2 2 1 1 3 3 3 0 Protein gp23 (Bacteriophage A118) Na_Ca_ex PF01699.19 OAJ27256.1 - 4.5e-24 84.6 33.1 8e-13 48.1 8.8 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 OAJ27256.1 - 1.7e-14 53.9 4.3 1.7e-14 53.9 3.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF307) Ycf1 PF05758.7 OAJ27256.1 - 9.7 3.7 4.6 14 3.2 3.2 1.2 1 0 0 1 1 1 0 Ycf1 Lipase_3 PF01764.20 OAJ27257.1 - 1.1e-05 25.1 0.1 4.4e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) Ctf8 PF09696.5 OAJ27258.1 - 0.00038 20.2 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 Ctf8 CDK2AP PF09806.4 OAJ27258.1 - 0.007 16.6 2.8 0.007 16.6 2.0 2.5 2 1 0 2 2 2 1 Cyclin-dependent kinase 2-associated protein Nucleoplasmin PF03066.10 OAJ27258.1 - 0.02 14.3 7.6 0.045 13.2 5.3 1.6 1 0 0 1 1 1 0 Nucleoplasmin DUF3357 PF11837.3 OAJ27258.1 - 0.027 14.2 2.9 0.72 9.7 0.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) FAM176 PF14851.1 OAJ27258.1 - 0.077 12.6 6.7 36 4.0 0.1 3.3 3 0 0 3 3 3 0 FAM176 family SpoIIIAH PF12685.2 OAJ27258.1 - 0.58 9.6 7.1 3.3 7.1 0.6 3.0 3 0 0 3 3 3 0 SpoIIIAH-like protein DUF4366 PF14283.1 OAJ27258.1 - 0.66 9.3 0.0 0.66 9.3 0.0 3.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4366) CDC45 PF02724.9 OAJ27258.1 - 1.3 6.9 24.9 0.031 12.3 9.5 2.2 2 0 0 2 2 2 0 CDC45-like protein DUF1510 PF07423.6 OAJ27258.1 - 2.3 7.5 14.8 1.6 8.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 OAJ27258.1 - 2.7 5.8 20.9 0.1 10.5 8.2 2.0 2 0 0 2 2 2 0 Nop14-like family Macoilin PF09726.4 OAJ27258.1 - 3.1 5.9 5.3 6.1 4.9 3.7 1.4 1 0 0 1 1 1 0 Transmembrane protein Cwf_Cwc_15 PF04889.7 OAJ27258.1 - 8.5 6.0 16.2 14 5.2 6.7 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Phage_holin_2 PF04550.7 OAJ27259.1 - 0.041 13.9 6.0 3.7 7.7 0.2 3.1 2 1 1 3 3 3 0 Phage holin family 2 Lipase_3 PF01764.20 OAJ27260.1 - 6.4e-11 42.0 0.0 4.3e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) Colicin_immun PF09204.5 OAJ27260.1 - 0.18 11.8 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial self-protective colicin-like immunity RVT_3 PF13456.1 OAJ27261.1 - 0.0098 15.6 0.1 0.03 14.0 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like zf-CCHC_4 PF14392.1 OAJ27261.1 - 1.8 8.3 5.5 0.27 10.9 0.9 1.8 2 0 0 2 2 2 0 Zinc knuckle CAF-1_p150 PF11600.3 OAJ27262.1 - 0.00058 19.3 0.8 0.00089 18.7 0.6 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Amidase PF01425.16 OAJ27263.1 - 1.2e-94 317.7 0.8 1.8e-94 317.1 0.6 1.2 1 0 0 1 1 1 1 Amidase Pyrid_oxidase_2 PF13883.1 OAJ27264.1 - 5.3e-25 88.1 0.0 7.2e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Kelch_2 PF07646.10 OAJ27264.1 - 0.038 13.7 0.8 1.5 8.7 0.3 2.9 2 1 0 2 2 2 0 Kelch motif ATP-synt_J PF04911.7 OAJ27264.1 - 0.069 12.6 0.6 0.33 10.4 0.0 2.3 2 1 0 2 2 2 0 ATP synthase j chain GDI PF00996.13 OAJ27265.1 - 8.5e-195 647.1 0.0 1e-194 646.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 OAJ27265.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain p450 PF00067.17 OAJ27266.1 - 6.9e-22 77.5 0.0 2.5e-21 75.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 NOA36 PF06524.7 OAJ27267.1 - 3.6 6.7 4.5 6.4 5.9 3.1 1.3 1 0 0 1 1 1 0 NOA36 protein TB2_DP1_HVA22 PF03134.14 OAJ27268.1 - 1.4e-31 108.0 4.9 1.8e-31 107.7 3.4 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Polysacc_synt_C PF14667.1 OAJ27268.1 - 0.045 13.5 3.7 0.064 13.0 2.6 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Rrn6 PF10214.4 OAJ27269.1 - 0.00017 19.8 8.1 0.15 10.1 0.2 3.5 2 2 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor DDE_3 PF13358.1 OAJ27270.1 - 2.9e-29 101.7 0.0 4.3e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 OAJ27270.1 - 8.1e-07 28.4 0.0 1.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix rve PF00665.21 OAJ27270.1 - 1.4e-06 28.4 0.0 3.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.1 OAJ27270.1 - 3.1e-05 24.6 0.0 9.4e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain DDE_Tnp_ISAZ013 PF07592.6 OAJ27270.1 - 0.0006 18.6 0.1 0.067 11.9 0.0 2.1 2 0 0 2 2 2 2 Rhodopirellula transposase DDE domain DDE_1 PF03184.14 OAJ27270.1 - 0.0043 16.2 0.0 0.0062 15.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_IS630 PF01710.11 OAJ27270.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Transposase KH_3 PF13014.1 OAJ27270.1 - 0.08 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 KH domain ECH PF00378.15 OAJ27271.1 - 3.4e-51 173.7 0.0 4.7e-45 153.6 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 OAJ27271.1 - 0.0095 16.0 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region AMP-binding PF00501.23 OAJ27272.1 - 3.5e-59 200.2 0.0 4.5e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ27272.1 - 9.5e-12 45.7 0.1 2.4e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 OAJ27273.1 - 6.9e-82 275.0 0.0 9.1e-82 274.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ27273.1 - 8e-08 33.1 0.0 3.5e-07 31.0 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pil1 PF13805.1 OAJ27274.1 - 2.3e-05 23.6 3.0 7.6e-05 21.9 2.1 1.8 1 0 0 1 1 1 1 Eisosome component PIL1 zf-FCS PF06467.9 OAJ27275.1 - 1.1 8.9 4.5 23 4.7 0.0 2.7 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif FHA PF00498.21 OAJ27277.1 - 1.6e-08 34.5 0.0 2e-07 31.0 0.0 2.3 1 1 0 1 1 1 1 FHA domain Gti1_Pac2 PF09729.4 OAJ27278.1 - 1.2e-55 187.9 0.0 2.2e-55 187.0 0.0 1.5 1 0 0 1 1 1 1 Gti1/Pac2 family AMP-binding PF00501.23 OAJ27279.1 - 9.7e-08 30.8 0.0 1.1e-07 30.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme GSHPx PF00255.14 OAJ27280.1 - 3.5e-31 106.7 0.1 4.5e-31 106.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.5 OAJ27280.1 - 1.7e-05 24.3 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAJ27280.1 - 0.00016 21.3 0.1 0.00046 19.8 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.1 OAJ27280.1 - 0.081 13.0 0.1 0.097 12.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) Acyl-CoA_dh_1 PF00441.19 OAJ27281.1 - 1.1e-31 109.9 0.2 1.8e-31 109.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ27281.1 - 5.3e-16 57.8 0.2 1.3e-15 56.6 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 OAJ27281.1 - 6.2e-16 57.9 0.0 1.5e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 OAJ27281.1 - 4.6e-12 46.5 0.5 2.5e-11 44.1 0.0 2.5 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAJ27281.1 - 9.4e-05 22.6 0.1 0.00017 21.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyto_heme_lyase PF01265.12 OAJ27282.1 - 2.5e-63 214.0 0.0 3.3e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase MMtag PF10159.4 OAJ27283.1 - 2e-31 107.8 3.0 2e-31 107.8 2.1 3.5 2 1 1 3 3 3 1 Kinase phosphorylation protein DUF4042 PF13251.1 OAJ27284.1 - 5.3e-09 35.8 3.6 3e-08 33.3 0.1 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.1 OAJ27284.1 - 7.9e-07 29.2 35.7 0.19 12.0 2.3 6.6 3 2 3 6 6 6 5 HEAT repeats HEAT PF02985.17 OAJ27284.1 - 6.8e-06 25.7 24.8 0.98 9.6 0.2 8.5 8 0 0 8 8 8 4 HEAT repeat PQ-loop PF04193.9 OAJ27285.1 - 6.6e-14 51.1 0.2 1.8e-12 46.5 0.1 2.6 2 0 0 2 2 2 1 PQ loop repeat Amidinotransf PF02274.12 OAJ27286.1 - 1.2e-21 77.0 0.0 5e-21 75.0 0.0 1.7 1 1 0 1 1 1 1 Amidinotransferase Transket_pyr PF02779.19 OAJ27287.1 - 4.4e-60 202.2 0.0 7e-60 201.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 OAJ27287.1 - 4.8e-43 147.0 0.0 1.5e-42 145.3 0.0 1.7 2 0 0 2 2 2 1 Dehydrogenase E1 component Pkinase PF00069.20 OAJ27288.1 - 3.2e-45 154.2 0.0 6e-45 153.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ27288.1 - 1.3e-17 63.7 0.0 1.9e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ27288.1 - 0.0014 17.6 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 OAJ27288.1 - 0.0033 16.7 0.0 0.0066 15.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family DUF294_C PF10335.4 OAJ27288.1 - 0.07 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain Choline_kinase PF01633.15 OAJ27288.1 - 0.18 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DAHP_synth_1 PF00793.15 OAJ27289.1 - 2.8e-92 308.2 0.0 3.4e-92 307.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family HECT PF00632.20 OAJ27291.1 - 0.031 13.4 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) Ribosomal_L4 PF00573.17 OAJ27292.1 - 1e-43 148.9 0.4 1e-43 148.9 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 OAJ27292.1 - 3.5e-28 97.2 1.1 1.1e-27 95.7 0.5 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Pox_Ag35 PF03286.9 OAJ27293.1 - 1.1 8.6 5.7 0.2 11.1 0.8 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SDA1 PF05285.7 OAJ27293.1 - 3.7 6.7 10.0 0.81 8.9 0.6 2.1 2 0 0 2 2 2 0 SDA1 AAA PF00004.24 OAJ27294.1 - 2.5e-47 160.3 0.0 1.9e-41 141.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ27294.1 - 4.9e-07 29.9 0.2 2.6e-05 24.3 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 OAJ27294.1 - 1.3e-05 25.1 0.0 4.4e-05 23.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 OAJ27294.1 - 2.1e-05 24.5 0.0 0.056 13.4 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 OAJ27294.1 - 9e-05 21.9 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 OAJ27294.1 - 0.00013 22.1 0.6 0.0094 16.0 0.1 3.4 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.1 OAJ27294.1 - 0.00077 19.1 0.1 0.0033 17.1 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 OAJ27294.1 - 0.0014 18.3 0.0 0.0062 16.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 OAJ27294.1 - 0.0028 17.0 0.1 0.016 14.5 0.0 2.4 3 0 0 3 3 1 1 AAA domain Sigma54_activat PF00158.21 OAJ27294.1 - 0.0039 16.6 0.0 0.86 9.0 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_33 PF13671.1 OAJ27294.1 - 0.0052 16.6 0.1 0.023 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ27294.1 - 0.0056 17.4 0.0 0.03 15.1 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ27294.1 - 0.015 15.5 0.0 0.049 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 OAJ27294.1 - 0.019 15.2 0.1 0.13 12.6 0.0 2.4 3 0 0 3 3 2 0 ABC transporter AAA_14 PF13173.1 OAJ27294.1 - 0.041 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAJ27294.1 - 0.054 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Bromodomain PF00439.20 OAJ27294.1 - 0.055 13.3 0.2 0.15 11.9 0.1 1.8 2 0 0 2 2 1 0 Bromodomain TIP49 PF06068.8 OAJ27294.1 - 0.067 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 OAJ27294.1 - 0.088 11.9 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.6 OAJ27294.1 - 0.1 12.4 0.1 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Torsin PhoH PF02562.11 OAJ27294.1 - 0.13 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 OAJ27294.1 - 0.18 11.6 0.4 0.79 9.5 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PHD PF00628.24 OAJ27296.1 - 1.2e-10 40.8 8.4 2.3e-10 39.9 5.8 1.5 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.3 OAJ27296.1 - 0.00027 20.4 0.0 0.00027 20.4 0.0 2.4 3 0 0 3 3 3 1 CpG binding protein zinc finger C terminal domain PHD_2 PF13831.1 OAJ27296.1 - 0.11 11.8 2.4 0.19 11.0 1.7 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.1 OAJ27297.1 - 2.2e-31 108.0 7.0 2.2e-31 108.0 4.8 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 OAJ27297.1 - 3.8e-23 81.4 5.5 3.8e-23 81.4 3.8 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 OAJ27297.1 - 3.7e-21 76.0 0.5 3.7e-21 76.0 0.3 4.0 4 1 0 4 4 4 1 Enhancer of polycomb-like Bromodomain PF00439.20 OAJ27297.1 - 2.1e-20 72.4 0.1 4.4e-20 71.4 0.1 1.5 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.1 OAJ27297.1 - 3.3e-13 48.6 2.1 3.3e-13 48.6 1.4 2.6 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.12 OAJ27297.1 - 8.7e-11 41.8 0.1 3.2e-10 40.0 0.0 2.1 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 OAJ27297.1 - 1.2e-08 34.4 8.9 1.2e-08 34.4 6.2 2.7 2 0 0 2 2 2 1 PHD-finger PPP4R2 PF09184.6 OAJ27297.1 - 6.4 6.2 29.3 17 4.8 20.3 1.8 1 0 0 1 1 1 0 PPP4R2 4HBT PF03061.17 OAJ27298.1 - 2e-11 43.8 0.0 3.8e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DUF3659 PF12396.3 OAJ27298.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) MaoC_dehydratas PF01575.14 OAJ27298.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain DnaJ PF00226.26 OAJ27299.1 - 6.2e-27 93.1 1.5 9.2e-27 92.5 1.0 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 OAJ27299.1 - 1.9e-09 37.2 0.0 8.9e-06 25.5 0.0 2.9 2 1 0 2 2 2 2 DnaJ C terminal domain MFS_1 PF07690.11 OAJ27300.1 - 1.2e-31 109.7 28.8 1.2e-31 109.7 20.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily LRRC37AB_C PF14914.1 OAJ27300.1 - 0.061 12.7 0.2 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Vpu PF00558.14 OAJ27300.1 - 0.25 10.9 1.4 10 5.7 0.0 3.0 3 0 0 3 3 3 0 Vpu protein DUF202 PF02656.10 OAJ27300.1 - 4.6 7.5 10.3 29 4.9 0.5 4.4 2 2 2 4 4 4 0 Domain of unknown function (DUF202) Helicase_C PF00271.26 OAJ27301.1 - 4.1e-15 55.4 0.0 8.3e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDC45 PF02724.9 OAJ27301.1 - 0.56 8.1 3.2 0.76 7.7 2.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Sec7_N PF12783.2 OAJ27302.1 - 5.5e-29 100.7 1.7 2.4e-28 98.6 0.0 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 OAJ27302.1 - 0.00085 18.7 0.0 0.01 15.3 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) Cyclin PF08613.6 OAJ27303.1 - 4.3e-28 98.5 0.1 7.4e-28 97.8 0.1 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 OAJ27303.1 - 0.00013 21.5 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain OST3_OST6 PF04756.8 OAJ27304.1 - 8.4e-16 57.9 2.4 1.6e-15 57.0 1.6 1.4 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 OAJ27304.1 - 0.0012 18.4 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin HlyIII PF03006.15 OAJ27304.1 - 5.8 6.2 10.7 0.24 10.7 0.5 2.5 3 0 0 3 3 3 0 Haemolysin-III related Pribosyltran PF00156.22 OAJ27305.1 - 5.2e-19 68.1 0.4 1.1e-18 67.1 0.3 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain DHOase PF12890.2 OAJ27305.1 - 0.079 12.6 0.0 0.53 9.9 0.0 2.0 1 1 1 2 2 2 0 Dihydro-orotase-like Yqai PF09466.5 OAJ27305.1 - 0.086 12.8 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Hypothetical protein Yqai OTU PF02338.14 OAJ27306.1 - 8.9e-16 58.5 0.0 1.4e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease DUF3618 PF12277.3 OAJ27306.1 - 0.12 12.4 4.9 4.2 7.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) 3Beta_HSD PF01073.14 OAJ27307.1 - 8e-60 201.9 0.0 7.2e-56 188.9 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAJ27307.1 - 2.1e-24 86.2 0.0 3.2e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ27307.1 - 8.9e-13 48.6 0.0 1.9e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAJ27307.1 - 1.2e-11 44.0 0.0 6.3e-08 31.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 OAJ27307.1 - 3.1e-07 30.4 0.0 8.4e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 OAJ27307.1 - 8.6e-06 24.8 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 OAJ27307.1 - 0.00065 19.4 0.0 0.0027 17.3 0.0 2.0 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.13 OAJ27307.1 - 0.0041 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.10 OAJ27307.1 - 0.0049 15.8 0.1 0.023 13.6 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 OAJ27307.1 - 0.023 13.9 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family DNA_pol_B_exo1 PF03104.14 OAJ27307.1 - 0.035 12.9 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain UBA_3 PF09288.5 OAJ27307.1 - 0.066 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain PNP_UDP_1 PF01048.15 OAJ27307.1 - 0.11 11.4 0.0 0.24 10.3 0.0 1.6 2 0 0 2 2 2 0 Phosphorylase superfamily Strep_his_triad PF04270.8 OAJ27307.1 - 0.11 12.2 0.3 0.37 10.5 0.1 2.0 2 0 0 2 2 2 0 Streptococcal histidine triad protein Cofilin_ADF PF00241.15 OAJ27308.1 - 5.4e-12 45.7 0.0 1.5e-05 24.8 0.0 2.6 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Secretin_N PF03958.12 OAJ27308.1 - 0.059 13.5 6.0 0.61 10.3 0.0 3.8 4 0 0 4 4 4 0 Bacterial type II/III secretion system short domain ArgK PF03308.11 OAJ27309.1 - 3.6e-06 25.9 0.1 5.5e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 OAJ27309.1 - 7e-05 23.6 0.1 0.0002 22.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 OAJ27309.1 - 0.00012 22.1 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 OAJ27309.1 - 0.00021 20.9 0.0 0.00053 19.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 OAJ27309.1 - 0.00024 20.9 0.0 0.00042 20.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase MobB PF03205.9 OAJ27309.1 - 0.00053 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 OAJ27309.1 - 0.0013 17.9 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 OAJ27309.1 - 0.003 17.8 0.0 0.0078 16.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.10 OAJ27309.1 - 0.0034 17.0 0.1 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 NTPase RNA_helicase PF00910.17 OAJ27309.1 - 0.0037 17.4 0.0 0.0077 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase KAP_NTPase PF07693.9 OAJ27309.1 - 0.0039 16.2 0.0 0.0039 16.2 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_14 PF13173.1 OAJ27309.1 - 0.0053 16.6 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 OAJ27309.1 - 0.0092 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NB-ARC PF00931.17 OAJ27309.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 OAJ27309.1 - 0.039 14.2 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_35 PF14516.1 OAJ27309.1 - 0.042 12.4 0.0 0.064 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 OAJ27309.1 - 0.047 13.5 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 OAJ27309.1 - 0.063 13.4 0.1 0.26 11.4 0.0 1.9 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ27309.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RPE65 PF03055.10 OAJ27310.1 - 3.9e-103 345.6 0.0 5.3e-103 345.1 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF3812 PF12757.2 OAJ27310.1 - 0.27 11.2 4.2 0.47 10.4 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3812) Syja_N PF02383.13 OAJ27311.1 - 9.1e-89 297.3 0.0 1.4e-88 296.7 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Phosphoesterase PF04185.9 OAJ27312.1 - 5.6e-29 101.4 3.1 1e-28 100.6 2.1 1.3 1 1 0 1 1 1 1 Phosphoesterase family Calcipressin PF04847.7 OAJ27312.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Calcipressin Histone PF00125.19 OAJ27313.1 - 1.3e-25 89.2 0.0 1.8e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAJ27313.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ING PF12998.2 OAJ27314.1 - 1.1e-13 51.3 0.4 2e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 OAJ27314.1 - 2.6e-08 33.4 10.9 4.3e-08 32.7 7.6 1.4 1 0 0 1 1 1 1 PHD-finger Histone PF00125.19 OAJ27315.1 - 1.4e-22 79.5 0.4 1.9e-22 79.1 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAJ27315.1 - 4.5e-07 29.8 0.1 8.5e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 OAJ27315.1 - 0.00037 20.7 0.0 0.00058 20.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 OAJ27315.1 - 0.034 14.6 0.3 0.045 14.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.8 OAJ27315.1 - 0.042 13.2 0.1 0.074 12.5 0.1 1.4 1 1 0 1 1 1 0 Replication protein C N-terminal domain AIRS PF00586.19 OAJ27316.1 - 2.2e-15 56.6 0.0 3.8e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Trehalase PF01204.13 OAJ27317.1 - 1.1e-170 568.7 0.2 1.4e-170 568.3 0.1 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 OAJ27317.1 - 6.3e-15 54.1 0.0 1e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Cpn60_TCP1 PF00118.19 OAJ27318.1 - 3.3e-143 477.8 0.3 3.8e-143 477.6 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.16 OAJ27318.1 - 0.086 12.6 0.4 1 9.1 0.1 2.6 2 0 0 2 2 2 0 Resolvase, N terminal domain Enolase_N PF03952.11 OAJ27318.1 - 0.52 10.2 3.9 32 4.4 0.1 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain