# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF3432 PF11914.3 AEO62176.1 - 6.3e-05 22.9 3.8 0.066 13.2 0.9 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3432) DUF3419 PF11899.3 AEO62177.1 - 0.034 12.8 0.0 0.059 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Glyco_hydro_31 PF01055.21 AEO62178.1 - 2.5e-86 290.2 0.1 3e-86 289.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 AEO62178.1 - 1.7e-13 50.2 0.0 5e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like Sugar_tr PF00083.19 AEO62179.1 - 4.6e-08 32.0 10.7 7.9e-08 31.3 7.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter NfeD PF01957.13 AEO62179.1 - 0.33 11.0 0.0 0.33 11.0 0.0 2.5 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding CFEM PF05730.6 AEO62180.1 - 6.8e-15 54.6 13.6 1.1e-14 53.9 9.5 1.4 1 0 0 1 1 1 1 CFEM domain AA_permease_2 PF13520.1 AEO62183.1 - 9.4e-78 261.6 25.7 1.2e-77 261.2 17.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO62183.1 - 4.1e-06 25.4 33.0 1.4e-05 23.6 22.9 2.1 1 1 0 1 1 1 1 Amino acid permease Cwf_Cwc_15 PF04889.7 AEO62184.1 - 0.13 11.9 8.7 0.14 11.8 3.8 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CobT PF06213.7 AEO62184.1 - 3.9 6.5 12.7 6.4 5.8 8.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAD_binding_4 PF01565.18 AEO62186.1 - 8.1e-25 86.9 4.5 8.1e-25 86.9 3.1 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 AEO62186.1 - 1.7e-11 43.8 0.1 4e-11 42.6 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cupin_1 PF00190.17 AEO62187.1 - 6.1e-24 84.0 0.0 2.1e-12 46.6 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 AEO62187.1 - 3.1e-22 77.8 0.1 7e-12 44.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 AEO62187.1 - 1.4e-07 30.7 0.1 0.00086 18.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 AEO62187.1 - 0.00014 21.5 0.0 0.0021 17.7 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.7 AEO62187.1 - 0.00061 19.2 0.0 0.0016 17.8 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase AraC_binding PF02311.14 AEO62187.1 - 0.014 15.0 0.1 0.25 11.0 0.0 2.5 3 0 0 3 3 3 0 AraC-like ligand binding domain SET PF00856.23 AEO62188.1 - 1.2e-12 48.4 0.0 8.8e-12 45.6 0.0 2.3 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 AEO62188.1 - 2.1e-07 30.8 0.2 3.7e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding KAT11 PF08214.6 AEO62189.1 - 4.9e-91 305.3 0.0 6.6e-91 304.9 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Ribonucleas_3_3 PF14622.1 AEO62190.1 - 3.1e-06 27.1 0.0 4.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like p450 PF00067.17 AEO62192.1 - 4.3e-54 183.7 0.0 6.3e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Mito_fiss_reg PF05308.6 AEO62192.1 - 0.19 11.0 1.7 0.33 10.2 1.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 AEO62192.1 - 0.32 10.2 2.7 0.55 9.4 1.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal 4HBT_3 PF13622.1 AEO62194.1 - 1.7e-50 172.1 1.4 1.9e-50 171.9 1.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF829 PF05705.9 AEO62195.1 - 2.4e-06 27.4 0.0 6e-06 26.1 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF829) F_bP_aldolase PF01116.15 AEO62196.1 - 6.2e-97 324.1 0.0 7e-97 323.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF3237 PF11578.3 AEO62197.1 - 5.9e-37 126.2 0.0 7.3e-37 125.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) SBP_bac_3 PF00497.15 AEO62199.1 - 4.4e-05 22.8 0.0 0.00011 21.5 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.2 AEO62199.1 - 0.0011 18.3 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.6 AEO62199.1 - 0.028 14.0 0.0 0.23 11.0 0.0 2.3 1 1 1 2 2 2 0 NMT1/THI5 like BNIP2 PF12496.3 AEO62199.1 - 0.033 14.3 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 ABM PF03992.11 AEO62200.1 - 1.8e-10 40.6 0.0 2.3e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SRP54 PF00448.17 AEO62201.1 - 1e-75 253.5 1.8 2.7e-75 252.1 0.5 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 AEO62201.1 - 1.1e-25 89.8 6.4 1.1e-25 89.8 4.5 3.3 3 1 2 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.14 AEO62201.1 - 1.7e-15 56.8 0.1 4.1e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 AEO62201.1 - 2e-08 33.8 0.1 5.8e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 AEO62201.1 - 5.3e-08 32.8 0.1 1.7e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 AEO62201.1 - 1.4e-05 24.8 0.0 3.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 AEO62201.1 - 2e-05 25.3 0.0 4.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 AEO62201.1 - 7.6e-05 22.2 0.1 0.00027 20.4 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 AEO62201.1 - 0.00023 20.0 1.2 0.0019 17.0 0.8 2.3 1 1 0 1 1 1 1 ArgK protein AAA_31 PF13614.1 AEO62201.1 - 0.0013 18.6 0.0 0.41 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 AEO62201.1 - 0.0014 18.3 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 AEO62201.1 - 0.0017 18.4 0.0 0.0075 16.4 0.0 2.2 2 0 0 2 2 1 1 AAA domain Thymidylate_kin PF02223.12 AEO62201.1 - 0.003 16.9 0.1 0.021 14.2 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_16 PF13191.1 AEO62201.1 - 0.0051 16.8 0.4 0.022 14.7 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 AEO62201.1 - 0.0062 16.1 0.2 0.04 13.4 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 AEO62201.1 - 0.0094 15.0 1.6 0.011 14.8 0.0 2.0 2 0 0 2 2 1 1 Zeta toxin AAA_18 PF13238.1 AEO62201.1 - 0.0094 16.2 0.0 0.022 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 AEO62201.1 - 0.011 14.9 0.8 2.3 7.3 0.5 3.1 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AEO62201.1 - 0.014 15.3 0.0 0.1 12.5 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.4 AEO62201.1 - 0.015 13.9 0.6 0.031 12.9 0.0 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.24 AEO62201.1 - 0.02 15.1 0.1 0.078 13.1 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 AEO62201.1 - 0.021 14.2 0.1 0.047 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA-like domain AAA_28 PF13521.1 AEO62201.1 - 0.028 14.3 0.2 0.062 13.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.13 AEO62201.1 - 0.046 12.7 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Torsin PF06309.6 AEO62201.1 - 0.065 13.1 0.0 0.18 11.6 0.0 1.7 1 1 0 1 1 1 0 Torsin AAA_19 PF13245.1 AEO62201.1 - 0.078 12.7 0.7 0.25 11.1 0.0 2.2 2 0 0 2 2 1 0 Part of AAA domain VirE PF05272.6 AEO62201.1 - 0.12 11.8 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E DUF3574 PF12098.3 AEO62202.1 - 0.049 13.2 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) Adap_comp_sub PF00928.16 AEO62204.1 - 1.8e-90 302.5 0.0 2.4e-90 302.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AEO62204.1 - 4.8e-09 36.0 0.2 7.9e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 AEO62204.1 - 0.12 11.5 0.0 0.51 9.4 0.0 1.8 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Opi1 PF08618.5 AEO62205.1 - 1e-70 238.8 0.0 4.7e-41 141.1 0.1 4.0 2 1 2 4 4 4 3 Transcription factor Opi1 HAD_2 PF13419.1 AEO62206.1 - 1e-09 38.8 0.0 8.3e-05 22.8 0.0 2.8 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO62206.1 - 8.1e-07 28.6 0.0 1.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 AEO62206.1 - 0.12 12.7 0.0 0.49 10.7 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ThuA PF06283.6 AEO62208.1 - 8.4e-63 211.9 0.0 9.9e-63 211.7 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation DUF4159 PF13709.1 AEO62208.1 - 0.0081 15.2 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4159) DUF1355 PF07090.6 AEO62208.1 - 0.086 12.2 0.0 0.2 10.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1355) PLDc_2 PF13091.1 AEO62209.1 - 4.9e-22 78.0 0.0 1.3e-14 54.0 0.0 2.9 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.17 AEO62209.1 - 3.7e-06 26.5 0.1 0.00087 19.0 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Glyco_hydro_6 PF01341.12 AEO62210.1 - 2e-107 359.0 1.2 2.5e-107 358.7 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 AEO62210.1 - 4.5e-14 51.8 9.9 1.4e-13 50.2 6.9 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain MSP1_C PF07462.6 AEO62210.1 - 2.2 6.5 5.7 3.1 6.0 4.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Glyco_hydro_47 PF01532.15 AEO62211.1 - 3.3e-160 533.6 0.0 3.8e-160 533.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Thymidylate_kin PF02223.12 AEO62215.1 - 1.6e-42 145.0 0.0 7.7e-41 139.5 0.0 2.0 2 0 0 2 2 2 2 Thymidylate kinase AAA_28 PF13521.1 AEO62215.1 - 1.6e-05 24.9 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 AEO62215.1 - 0.0039 16.4 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.7 AEO62215.1 - 0.0083 15.7 0.0 0.017 14.7 0.0 1.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein GTP_cyclohydroI PF01227.17 AEO62216.1 - 1.3e-74 249.3 0.6 1.7e-74 248.9 0.4 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 AEO62216.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein DegT_DnrJ_EryC1 PF01041.12 AEO62216.1 - 0.09 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family TAFII28 PF04719.9 AEO62217.1 - 6.8e-28 96.3 0.4 4.6e-26 90.4 0.1 2.2 2 0 0 2 2 2 2 hTAFII28-like protein conserved region CENP-C_C PF11699.3 AEO62218.1 - 0.0054 16.6 0.0 0.0082 16.0 0.0 1.5 1 1 0 1 1 1 1 Mif2/CENP-C like Ribosomal_L27 PF01016.14 AEO62219.1 - 2.4e-23 81.7 0.5 4.3e-23 80.8 0.3 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein IPP-2 PF04979.9 AEO62219.1 - 2.7e-08 34.1 9.3 3.7e-06 27.2 0.3 3.8 4 0 0 4 4 4 2 Protein phosphatase inhibitor 2 (IPP-2) Sugar_tr PF00083.19 AEO62220.1 - 4.6e-82 275.9 17.8 5.6e-82 275.7 12.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO62220.1 - 1.3e-15 57.0 35.6 8.7e-12 44.4 7.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 AEO62221.1 - 1.2e-07 30.7 3.0 8.1e-06 24.6 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain ECSIT PF06239.6 AEO62221.1 - 0.039 12.8 0.0 0.08 11.7 0.0 1.4 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway PARP PF00644.15 AEO62222.1 - 3.2e-55 186.7 0.0 6.9e-55 185.6 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 AEO62222.1 - 2.3e-44 150.3 0.2 3.9e-44 149.5 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 AEO62222.1 - 1.4e-21 76.2 0.1 4.2e-21 74.6 0.1 1.8 1 0 0 1 1 1 1 WGR domain Zn_clus PF00172.13 AEO62222.1 - 2.8e-13 49.5 24.1 2.8e-08 33.5 4.7 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO62222.1 - 6.5e-13 48.1 0.2 1.4e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain BRCT PF00533.21 AEO62222.1 - 4.8e-12 45.8 0.0 1.4e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AEO62222.1 - 1.3e-08 34.5 0.1 3.6e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 twin BRCT domain DUF2183 PF09949.4 AEO62223.1 - 3.7e-30 103.8 0.0 2.7e-29 101.0 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) GST_C_3 PF14497.1 AEO62224.1 - 9.6e-11 42.0 0.0 1.5e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AEO62224.1 - 2.4e-08 33.8 0.0 4.6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 AEO62224.1 - 4.2e-05 23.3 0.0 7.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AEO62224.1 - 4.8e-05 23.4 0.1 0.00053 20.1 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 AEO62224.1 - 0.033 14.4 0.0 0.089 13.0 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Adap_comp_sub PF00928.16 AEO62225.1 - 2.7e-85 285.6 0.0 3.6e-85 285.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AEO62225.1 - 1.4e-05 24.8 0.3 2.5e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 AEO62225.1 - 0.023 14.6 0.1 0.05 13.4 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) Bestrophin PF01062.16 AEO62226.1 - 3.5e-47 160.7 1.4 2.2e-45 154.8 1.0 2.1 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel RVT_2 PF07727.9 AEO62229.1 - 1.3e-12 47.2 1.5 1.6e-12 46.9 1.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Colicin_D PF11429.3 AEO62230.1 - 0.48 10.5 2.8 0.6 10.3 0.6 1.9 1 1 1 2 2 2 0 Colicin D UvdE PF03851.9 AEO62231.1 - 4.2e-119 396.6 0.0 5.5e-119 396.2 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE Glyco_hydro_31 PF01055.21 AEO62233.1 - 5.6e-11 41.9 0.0 6.1e-11 41.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DegV PF02645.11 AEO62233.1 - 0.1 11.6 0.0 0.12 11.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 zf-C2H2_4 PF13894.1 AEO62234.1 - 9.8e-08 31.8 13.9 0.25 11.7 0.8 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-TRAF PF02176.13 AEO62234.1 - 0.0033 17.7 1.4 0.0033 17.7 1.0 2.1 2 0 0 2 2 2 1 TRAF-type zinc finger zf-C2H2 PF00096.21 AEO62234.1 - 0.015 15.6 22.0 0.17 12.2 0.9 4.8 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO62234.1 - 0.052 13.8 9.0 7.3 7.0 0.0 4.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AEO62234.1 - 0.83 9.8 5.0 9.6 6.4 0.2 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Fungal_trans_2 PF11951.3 AEO62235.1 - 2e-13 49.7 0.0 1.1e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Patatin PF01734.17 AEO62236.1 - 8.4e-25 87.8 0.0 1.7e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase DUF4449 PF14613.1 AEO62237.1 - 8.9e-07 28.9 3.8 1.6e-05 24.9 0.1 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) Adeno_52K PF03052.10 AEO62237.1 - 0.0028 16.9 0.6 0.016 14.4 0.0 2.3 2 1 1 3 3 3 1 Adenoviral protein L1 52/55-kDa DUF1828 PF08861.5 AEO62237.1 - 0.0063 16.1 0.0 0.13 11.9 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF1828 Sec5 PF15469.1 AEO62237.1 - 0.14 11.8 0.9 15 5.2 0.0 2.9 3 0 0 3 3 3 0 Exocyst complex component Sec5 MARVEL PF01284.18 AEO62238.1 - 1.2e-16 60.8 16.3 1.5e-16 60.5 11.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain YpzI PF14140.1 AEO62239.1 - 0.0018 17.7 9.8 11 5.5 0.0 5.1 5 0 0 5 5 5 3 YpzI-like protein SKG6 PF08693.5 AEO62239.1 - 0.99 8.7 2.9 41 3.6 0.0 3.1 3 0 0 3 3 3 0 Transmembrane alpha-helix domain WD40 PF00400.27 AEO62240.1 - 1.8e-24 84.6 14.5 2.8e-08 33.3 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 AEO62240.1 - 0.0013 16.9 0.4 0.25 9.4 0.0 2.7 2 1 0 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 AEO62240.1 - 0.014 15.1 0.0 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 AEO62240.1 - 0.03 13.7 0.4 0.082 12.3 0.3 1.8 1 1 0 1 1 1 0 PQQ-like domain PQQ_3 PF13570.1 AEO62240.1 - 2.4 8.5 12.5 0.74 10.1 0.2 3.9 4 0 0 4 4 4 0 PQQ-like domain Zn_clus PF00172.13 AEO62243.1 - 3.6e-08 33.1 12.9 5.5e-08 32.6 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG16 PF08614.6 AEO62243.1 - 0.1 12.4 0.8 0.19 11.5 0.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) APG5 PF04106.7 AEO62244.1 - 3.7e-44 150.5 0.0 6.4e-43 146.5 0.0 2.1 1 1 0 1 1 1 1 Autophagy protein Apg5 ORMDL PF04061.9 AEO62247.1 - 4.8e-61 204.2 2.4 5.6e-61 204.0 1.7 1.0 1 0 0 1 1 1 1 ORMDL family TarH PF02203.10 AEO62248.1 - 0.012 15.4 0.7 0.018 14.8 0.5 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue HATPase_c PF02518.21 AEO62250.1 - 3.3e-29 100.8 0.0 9.9e-29 99.2 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 AEO62250.1 - 4.5e-28 97.4 0.1 7.7e-28 96.7 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 AEO62250.1 - 1.1e-13 50.9 0.0 2.5e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 AEO62250.1 - 5.9e-08 32.7 4.6 0.005 16.9 0.3 3.4 3 0 0 3 3 3 2 HAMP domain CMD PF02627.15 AEO62251.1 - 3.1e-09 36.5 0.3 3.3e-08 33.2 0.1 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family BRCA2 PF00634.13 AEO62251.1 - 0.09 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 BRCA2 repeat APH PF01636.18 AEO62253.1 - 5.2e-10 39.4 1.2 9.9e-05 22.1 0.3 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.20 AEO62253.1 - 5.7e-08 32.2 0.0 8.6e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 AEO62253.1 - 4.2e-07 29.2 0.0 0.00049 19.2 0.0 2.4 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AEO62253.1 - 0.0005 19.4 0.0 0.77 9.0 0.0 2.6 3 0 0 3 3 3 2 RIO1 family Pkinase_Tyr PF07714.12 AEO62253.1 - 0.0016 17.5 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Aldo_ket_red PF00248.16 AEO62254.1 - 2.8e-12 46.0 0.0 3.8e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.15 AEO62255.1 - 1.5e-51 173.8 1.4 1.8e-51 173.6 1.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Maf1 PF09174.5 AEO62256.1 - 1.2e-62 210.9 0.0 2.3e-62 210.0 0.0 1.5 1 0 0 1 1 1 1 Maf1 regulator Nop14 PF04147.7 AEO62256.1 - 0.25 9.2 12.1 0.33 8.8 8.4 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 AEO62256.1 - 2.5 7.2 11.7 3.9 6.6 8.1 1.2 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 AEO62256.1 - 3 6.2 9.2 4.1 5.7 6.4 1.1 1 0 0 1 1 1 0 Daxx Family PP2C PF00481.16 AEO62257.1 - 1.2e-82 277.1 0.2 2.1e-82 276.3 0.0 1.4 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 AEO62257.1 - 0.0013 18.1 0.0 0.0033 16.8 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C He_PIG PF05345.7 AEO62258.1 - 6.9e-16 58.0 16.8 1.4e-06 28.2 0.9 5.9 5 0 0 5 5 5 4 Putative Ig domain Sarcoglycan_2 PF05510.8 AEO62258.1 - 0.56 8.4 1.2 1.4 7.1 0.0 2.2 3 0 0 3 3 3 0 Sarcoglycan alpha/epsilon TadE PF07811.7 AEO62258.1 - 0.61 10.0 2.4 1.1 9.1 1.7 1.4 1 0 0 1 1 1 0 TadE-like protein Methyltransf_16 PF10294.4 AEO62259.1 - 1.7e-46 157.8 0.0 2e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 AEO62259.1 - 0.0036 16.6 0.0 0.0052 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 AEO62259.1 - 0.02 15.4 0.1 0.04 14.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 AEO62259.1 - 0.025 14.6 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 AEO62259.1 - 0.039 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Barwin PF00967.12 AEO62260.1 - 0.041 13.5 0.3 0.054 13.1 0.2 1.2 1 0 0 1 1 1 0 Barwin family Serglycin PF04360.7 AEO62260.1 - 2.7 7.7 7.4 3.8 7.2 5.1 1.3 1 0 0 1 1 1 0 Serglycin DUF1517 PF07466.6 AEO62260.1 - 2.7 6.9 4.9 3.2 6.6 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF1712 PF08217.6 AEO62261.1 - 1.1e-11 43.7 0.0 5.3e-10 38.1 0.0 2.7 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1712) PPR_2 PF13041.1 AEO62262.1 - 3.7e-07 30.0 0.1 0.00081 19.3 0.0 2.9 2 1 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 AEO62262.1 - 8.2e-06 25.7 1.5 2.3 8.7 0.0 4.0 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 AEO62262.1 - 4.5e-05 23.1 0.2 0.63 10.1 0.0 3.5 3 0 0 3 3 3 2 PPR repeat PPR_1 PF12854.2 AEO62262.1 - 0.0032 16.9 0.2 0.11 12.0 0.0 2.7 3 0 0 3 3 3 1 PPR repeat Clathrin PF00637.15 AEO62262.1 - 0.25 10.9 0.0 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS Pex24p PF06398.6 AEO62263.1 - 0.0016 17.2 9.6 0.0016 17.2 6.7 1.5 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin DUF4476 PF14771.1 AEO62263.1 - 0.091 12.8 0.1 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) LXG PF04740.7 AEO62264.1 - 0.012 15.3 0.1 0.015 15.1 0.1 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF4640 PF15480.1 AEO62264.1 - 0.031 13.8 0.2 0.042 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) YkyA PF10368.4 AEO62264.1 - 0.076 12.3 2.4 0.095 12.0 1.7 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Apolipoprotein PF01442.13 AEO62264.1 - 0.084 12.3 0.1 0.097 12.1 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PRP1_N PF06424.7 AEO62265.1 - 4.4e-49 166.2 6.9 1e-48 165.0 4.7 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 AEO62265.1 - 3.2e-35 117.3 46.9 0.00025 21.4 0.0 14.8 4 3 11 15 15 15 11 Tetratricopeptide repeat TPR_19 PF14559.1 AEO62265.1 - 5.5e-27 93.8 26.6 2.2e-06 27.8 0.1 9.6 8 2 1 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 AEO62265.1 - 4.4e-24 84.5 31.7 2.6e-06 27.9 0.0 9.5 6 1 4 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 AEO62265.1 - 1.1e-12 46.8 14.8 0.067 13.1 0.0 11.6 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_11 PF13414.1 AEO62265.1 - 6.2e-12 44.9 19.2 0.00088 18.8 0.0 9.0 6 3 3 9 9 9 3 TPR repeat TPR_8 PF13181.1 AEO62265.1 - 1.8e-07 30.4 0.0 0.1 12.3 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat NARP1 PF12569.3 AEO62265.1 - 2.3e-06 26.6 15.9 0.079 11.7 0.0 6.3 3 1 3 6 6 6 2 NMDA receptor-regulated protein 1 TPR_17 PF13431.1 AEO62265.1 - 2.4e-06 27.3 8.1 5.2 7.5 0.0 10.3 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_15 PF13429.1 AEO62265.1 - 2.8e-06 26.6 21.8 0.0024 16.9 0.8 5.8 2 2 4 6 6 6 3 Tetratricopeptide repeat NRDE-2 PF08424.5 AEO62265.1 - 1.6e-05 23.9 20.7 0.019 13.8 0.0 5.9 4 2 2 6 6 6 3 NRDE-2, necessary for RNA interference TPR_9 PF13371.1 AEO62265.1 - 1.9e-05 24.4 17.9 0.013 15.3 0.0 7.8 7 2 1 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 AEO62265.1 - 2e-05 24.0 0.9 0.11 12.1 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 AEO62265.1 - 2.2e-05 24.6 14.9 1.5 9.4 0.0 9.9 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_12 PF13424.1 AEO62265.1 - 5.6e-05 23.0 17.6 0.031 14.2 0.1 8.2 7 4 0 8 8 8 2 Tetratricopeptide repeat Suf PF05843.9 AEO62265.1 - 8.2e-05 22.4 0.1 17 4.9 0.0 5.0 4 1 1 5 5 5 0 Suppressor of forked protein (Suf) TPR_21 PF09976.4 AEO62265.1 - 0.0016 18.3 1.0 0.0016 18.3 0.7 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.5 AEO62265.1 - 0.17 10.6 5.8 5.3 5.6 0.0 3.8 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.1 AEO62265.1 - 0.17 11.7 2.8 35 4.5 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat FUSC_2 PF13515.1 AEO62266.1 - 2.1e-24 85.8 6.2 2.1e-24 85.8 4.3 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 AEO62266.1 - 4e-05 22.2 5.6 4e-05 22.2 3.9 3.1 3 1 1 4 4 4 1 Fusaric acid resistance protein family ALMT PF11744.3 AEO62266.1 - 0.0042 15.8 2.0 0.0042 15.8 1.4 3.5 3 1 0 3 3 3 2 Aluminium activated malate transporter DUF2421 PF10334.4 AEO62266.1 - 0.037 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) DUF2422 PF10337.4 AEO62266.1 - 0.15 10.8 8.3 0.69 8.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) DUF2248 PF10005.4 AEO62266.1 - 0.25 10.1 1.7 0.37 9.6 0.4 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2248) HAD_2 PF13419.1 AEO62267.1 - 4e-13 49.9 0.1 7.8e-09 35.9 0.0 2.8 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO62267.1 - 1.4e-07 31.0 0.8 4.4e-07 29.5 0.4 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 AEO62267.1 - 4e-06 27.3 0.2 0.025 14.9 0.0 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 AEO62267.1 - 6.2e-05 23.2 0.1 0.00018 21.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 AEO62267.1 - 0.15 11.3 0.0 5 6.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Pkinase PF00069.20 AEO62268.1 - 4.3e-61 206.3 0.0 5.3e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO62268.1 - 5.9e-40 136.9 0.0 7.9e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO62268.1 - 3.9e-06 26.0 0.0 6.1e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 AEO62268.1 - 0.078 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SH2_2 PF14633.1 AEO62269.1 - 3.5e-83 278.0 0.2 3.5e-83 278.0 0.1 2.3 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 AEO62269.1 - 8.7e-36 122.5 3.4 8.7e-36 122.5 2.4 4.7 5 0 0 5 5 5 1 Death-like domain of SPT6 YqgF PF14639.1 AEO62269.1 - 3.6e-31 107.7 0.0 1.1e-30 106.1 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 AEO62269.1 - 1.6e-29 102.1 0.0 3.8e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 AEO62269.1 - 4.2e-25 87.7 35.8 4.2e-25 87.7 24.8 5.5 5 1 0 5 5 5 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 AEO62269.1 - 3.1e-18 65.9 1.1 2.3e-17 63.0 0.8 2.5 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 S1 PF00575.18 AEO62269.1 - 6.8e-05 22.8 0.1 0.0002 21.3 0.1 1.8 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.19 AEO62269.1 - 0.00023 20.9 0.0 0.0007 19.3 0.0 1.9 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 AEO62269.1 - 0.0045 16.8 0.0 0.013 15.4 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Oxysterol_BP PF01237.13 AEO62270.1 - 5.9e-106 353.9 0.0 1.5e-105 352.6 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 AEO62270.1 - 5.3e-39 132.1 0.5 2.1e-38 130.2 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 AEO62270.1 - 2e-05 24.7 0.0 5.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 AEO62270.1 - 0.002 18.3 1.3 0.057 13.6 0.9 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Hydantoinase_B PF02538.9 AEO62271.1 - 2.6e-194 646.3 0.0 2.8e-189 629.7 0.0 2.1 2 0 0 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 AEO62271.1 - 7.6e-96 320.6 1.2 1.2e-95 319.9 0.3 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 AEO62271.1 - 7.1e-57 191.7 0.2 5.6e-55 185.5 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Vma12 PF11712.3 AEO62271.1 - 0.33 10.6 0.3 0.64 9.7 0.2 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pkinase PF00069.20 AEO62272.1 - 1.1e-76 257.4 0.0 1.4e-76 257.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO62272.1 - 1.1e-37 129.5 0.0 1.6e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 AEO62272.1 - 1.7e-16 60.0 0.4 3.9e-16 58.9 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 AEO62272.1 - 8.8e-06 24.8 0.0 2.7e-05 23.2 0.0 1.7 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 AEO62272.1 - 0.00025 20.4 0.2 0.00048 19.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 AEO62272.1 - 0.0031 16.1 0.1 0.0046 15.5 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 AEO62272.1 - 0.14 11.8 5.3 0.32 10.6 0.2 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family DGF-1_C PF11040.3 AEO62272.1 - 0.75 9.7 3.5 0.31 10.9 0.2 2.0 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF92 PF01940.11 AEO62273.1 - 9.9e-68 227.6 7.9 1.6e-67 227.0 5.5 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF92 Abi PF02517.11 AEO62273.1 - 1.2 9.2 6.2 8.2 6.6 0.2 2.8 1 1 1 2 2 2 0 CAAX protease self-immunity DUF1525 PF07511.6 AEO62274.1 - 0.021 14.8 0.1 0.024 14.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) Zn_clus PF00172.13 AEO62275.1 - 0.00013 21.7 11.3 0.00013 21.7 7.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 AEO62277.1 - 0.0041 17.0 15.3 0.0041 17.0 10.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 AEO62278.1 - 1.1e-70 238.0 0.1 2.4e-70 236.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 AEO62278.1 - 4.5e-51 174.0 0.0 1e-50 172.9 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Thioesterase PF00975.15 AEO62278.1 - 1.4e-42 146.5 0.0 4.1e-42 144.9 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 AEO62278.1 - 1.5e-35 121.6 0.4 3.2e-35 120.5 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 AEO62278.1 - 2.9e-24 85.1 3.8 4.3e-12 46.1 0.4 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 AEO62278.1 - 1.4e-05 24.8 0.1 0.048 13.4 0.0 3.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 AEO62278.1 - 0.0022 17.0 0.1 0.0059 15.6 0.1 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Cu-oxidase_2 PF07731.9 AEO62279.1 - 9.4e-43 145.0 9.3 4.1e-37 126.7 2.4 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.10 AEO62279.1 - 8e-41 138.4 9.5 2.3e-37 127.3 0.1 4.2 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 AEO62279.1 - 3.7e-22 78.9 1.5 4.8e-21 75.3 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.1 AEO62279.1 - 0.0075 16.1 0.0 2.1 8.3 0.0 3.6 3 1 0 3 3 3 1 Cupredoxin-like domain DNA_pol_E_B PF04042.11 AEO62280.1 - 3.2e-65 219.2 0.0 4.4e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PXA PF02194.10 AEO62283.1 - 1.1e-36 126.1 2.3 1.7e-36 125.5 0.0 2.1 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 AEO62283.1 - 4.5e-18 65.3 0.7 1.1e-17 64.1 0.0 2.1 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 AEO62283.1 - 3.1e-05 23.7 0.0 0.00013 21.7 0.0 2.1 2 0 0 2 2 2 1 PX domain MFS_1 PF07690.11 AEO62284.1 - 2e-34 118.8 24.9 3e-34 118.2 17.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sensor PF13796.1 AEO62284.1 - 0.0017 18.0 1.3 0.0017 18.0 0.9 3.9 3 1 0 3 3 3 1 Putative sensor ADIP PF11559.3 AEO62285.1 - 2.3e-42 144.4 7.7 4.9e-42 143.3 5.3 1.6 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding IncA PF04156.9 AEO62285.1 - 0.06 12.9 6.2 0.15 11.6 4.3 1.6 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 AEO62285.1 - 1.6 7.5 10.3 3.2 6.6 7.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 AEO62285.1 - 2.3 7.1 6.7 4.1 6.3 4.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIVA PF05103.8 AEO62285.1 - 3 7.9 10.3 11 6.0 5.9 2.8 2 0 0 2 2 2 0 DivIVA protein RRP7 PF12923.2 AEO62286.1 - 2e-36 124.8 11.0 2e-36 124.8 7.6 2.0 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_6 PF14259.1 AEO62286.1 - 0.00041 20.2 0.0 0.052 13.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO62286.1 - 0.036 13.6 0.1 0.14 11.8 0.0 2.1 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOSC PF03473.12 AEO62287.1 - 6e-17 61.3 0.0 1.6e-07 30.8 0.0 2.8 3 0 0 3 3 3 2 MOSC domain Fer2 PF00111.22 AEO62287.1 - 1.9e-08 33.9 5.1 4.4e-08 32.7 3.6 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 AEO62287.1 - 4.2e-06 27.3 0.0 1.8e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 AEO62287.1 - 0.19 11.6 0.0 1.2 9.0 0.0 2.0 2 0 0 2 2 2 0 Ferric reductase NAD binding domain F-box PF00646.28 AEO62288.1 - 3.3e-06 26.5 1.5 8.2e-06 25.3 1.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 AEO62288.1 - 0.00079 19.1 1.0 0.0017 18.0 0.7 1.5 1 0 0 1 1 1 1 F-box-like BAR PF03114.13 AEO62289.1 - 3.3e-66 223.0 7.9 4e-66 222.8 5.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 AEO62289.1 - 7.1e-15 54.1 0.0 1.6e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AEO62289.1 - 1.3e-11 43.8 0.1 2.5e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AEO62289.1 - 2.7e-09 36.3 0.4 9.5e-09 34.6 0.0 2.1 3 0 0 3 3 3 1 Variant SH3 domain Peptidase_C50 PF03568.12 AEO62289.1 - 0.057 12.0 0.7 0.098 11.3 0.5 1.4 1 0 0 1 1 1 0 Peptidase family C50 Aminotran_5 PF00266.14 AEO62290.1 - 5.9e-95 318.1 0.0 7.3e-95 317.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AEO62290.1 - 1.7e-07 30.7 0.0 2.5e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 AEO62290.1 - 3.2e-05 23.1 0.0 0.00019 20.6 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 AEO62290.1 - 0.00033 19.2 0.0 0.00051 18.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain CsbD PF05532.7 AEO62291.1 - 8.4e-19 66.9 16.7 5.2e-08 32.4 1.3 3.3 2 1 1 3 3 3 3 CsbD-like DUF3154 PF11351.3 AEO62291.1 - 0.48 10.1 4.3 1.3 8.7 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3154) NmrA PF05368.8 AEO62292.1 - 7.8e-13 48.2 0.0 2.8e-12 46.4 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO62292.1 - 2.2e-09 37.5 0.0 5.3e-09 36.3 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 AEO62292.1 - 0.00021 20.4 0.0 0.0003 19.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 AEO62292.1 - 0.004 17.2 0.0 0.007 16.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 AEO62292.1 - 0.14 10.8 0.0 0.25 9.9 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DAO PF01266.19 AEO62294.1 - 2e-48 165.1 1.5 2.6e-48 164.7 1.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO62294.1 - 0.00015 20.7 2.3 0.0021 16.9 1.6 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 AEO62294.1 - 0.00026 21.1 0.0 0.0057 16.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase eIF-5_eIF-2B PF01873.12 AEO62295.1 - 1.2e-43 147.6 0.2 2e-43 146.9 0.2 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DNA_RNApol_7kD PF03604.8 AEO62295.1 - 0.16 11.4 1.2 0.39 10.2 0.8 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Arc_trans_TRASH PF08394.5 AEO62295.1 - 3.7 7.7 7.5 2.1 8.5 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain MARVEL PF01284.18 AEO62297.1 - 6.9e-23 81.0 15.0 8.6e-23 80.7 10.4 1.0 1 0 0 1 1 1 1 Membrane-associating domain PNGaseA PF12222.3 AEO62298.1 - 2e-136 455.2 1.4 2.6e-136 454.8 1.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1279 PF06916.8 AEO62299.1 - 2.4e-28 98.2 0.0 3.6e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) AIM24 PF01987.12 AEO62300.1 - 3.9e-49 167.0 0.1 4.9e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Aph-1 PF06105.7 AEO62300.1 - 0.11 11.7 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 Aph-1 protein Velvet PF11754.3 AEO62301.1 - 0.036 13.6 0.3 0.081 12.5 0.0 1.7 2 0 0 2 2 2 0 Velvet factor Fork_head_N PF08430.7 AEO62301.1 - 0.15 12.4 5.1 0.16 12.3 0.4 2.9 2 0 0 2 2 2 0 Forkhead N-terminal region F-box-like PF12937.2 AEO62302.1 - 5.1e-09 35.7 2.2 1.5e-08 34.2 1.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO62302.1 - 6.7e-08 32.0 2.7 1.1e-07 31.3 1.2 2.0 2 0 0 2 2 2 1 F-box domain Dpy-30 PF05186.8 AEO62302.1 - 0.007 15.8 0.2 0.035 13.5 0.0 2.3 2 0 0 2 2 2 1 Dpy-30 motif TPR_11 PF13414.1 AEO62302.1 - 0.042 13.5 0.6 0.63 9.7 0.1 2.5 2 0 0 2 2 2 0 TPR repeat B2 PF11473.3 AEO62302.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA binding protein B2 Pkinase PF00069.20 AEO62305.1 - 9.3e-59 198.6 0.0 1.4e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO62305.1 - 9.5e-22 77.3 0.0 1.9e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO62305.1 - 0.0096 15.6 0.0 0.049 13.3 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Flavi_NS2B PF01002.14 AEO62305.1 - 0.23 11.0 0.0 0.39 10.3 0.0 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B Choline_kinase PF01633.15 AEO62305.1 - 0.26 10.8 3.9 0.096 12.2 0.7 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pex24p PF06398.6 AEO62306.1 - 3.9e-86 289.0 7.7 4.9e-58 196.6 0.0 2.1 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin polyprenyl_synt PF00348.12 AEO62307.1 - 5.2e-65 218.8 0.0 6.4e-65 218.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CDC14 PF08045.6 AEO62308.1 - 9.4e-86 287.1 0.0 1.1e-85 286.8 0.0 1.1 1 0 0 1 1 1 1 Cell division control protein 14, SIN component MFS_1 PF07690.11 AEO62310.1 - 5.9e-42 143.6 28.1 5.9e-42 143.6 19.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.17 AEO62311.1 - 5.8e-13 47.9 12.9 2.7e-09 35.8 6.5 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Kinetocho_Slk19 PF12709.2 AEO62312.1 - 1.4e-21 76.3 4.4 1.4e-21 76.3 3.1 4.7 4 1 0 5 5 5 2 Central kinetochore-associated Tropomyosin_1 PF12718.2 AEO62312.1 - 0.00078 19.3 12.3 0.00078 19.3 8.5 3.8 4 1 1 5 5 5 1 Tropomyosin like FlaC_arch PF05377.6 AEO62312.1 - 0.1 12.4 21.7 0.16 11.8 1.0 4.5 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Shugoshin_N PF07558.6 AEO62312.1 - 0.11 12.2 1.2 2.5 7.8 0.3 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region NYD-SP28_assoc PF14775.1 AEO62312.1 - 0.12 12.0 2.4 1.1 8.9 0.4 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain Pkinase PF00069.20 AEO62313.1 - 4.8e-40 137.3 0.0 6.9e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO62313.1 - 1.2e-12 47.4 0.0 1.6e-11 43.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 AEO62313.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase KilA-N PF04383.8 AEO62314.1 - 0.00081 18.9 0.0 0.0088 15.6 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain PTCB-BRCT PF12738.2 AEO62315.1 - 4.5e-05 23.2 0.7 0.0002 21.1 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 AEO62315.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF1764 PF08576.5 AEO62315.1 - 0.12 13.1 0.2 0.23 12.2 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) AMP-binding PF00501.23 AEO62316.1 - 1.2e-77 261.0 0.0 1.5e-77 260.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO62316.1 - 7.9e-11 42.7 0.4 5.6e-10 40.0 0.2 2.5 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cys_knot PF00007.17 AEO62317.1 - 0.035 14.1 2.9 0.05 13.6 2.0 1.3 1 1 0 1 1 1 0 Cystine-knot domain Endonuc-BsobI PF09194.5 AEO62318.1 - 0.11 11.4 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease BsobI ADH_zinc_N PF00107.21 AEO62319.1 - 6.7e-26 90.3 0.3 1.3e-25 89.4 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO62319.1 - 1.1e-19 71.5 0.0 2.8e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO62319.1 - 2.8e-09 36.7 0.0 1.9e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DLH PF01738.13 AEO62320.1 - 6e-10 38.7 0.6 8.8e-08 31.6 0.4 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AEO62320.1 - 9.6e-05 22.1 0.3 0.00011 21.9 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO62320.1 - 0.0018 18.2 4.2 0.053 13.3 1.1 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 AEO62320.1 - 0.022 14.3 0.0 0.05 13.1 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 AEO62320.1 - 0.059 12.9 0.8 0.36 10.3 0.3 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold IL34 PF15036.1 AEO62321.1 - 0.019 14.5 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Interleukin 34 MBF1 PF08523.5 AEO62322.1 - 1.3e-22 79.5 0.8 2.7e-22 78.5 0.6 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 AEO62322.1 - 2.8e-12 46.2 0.0 5.2e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 AEO62322.1 - 4.9e-06 26.6 0.1 9e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 AEO62322.1 - 0.00014 21.8 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 AEO62322.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF1365 PF07103.6 AEO62323.1 - 1.8e-32 112.3 0.0 8.1e-31 106.9 0.0 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) GFA PF04828.9 AEO62324.1 - 4.3e-22 77.8 0.0 6.2e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 AEO62324.1 - 0.13 11.9 0.1 0.13 11.9 0.0 2.6 3 0 0 3 3 3 0 Nudix N-terminal INO80_Ies4 PF08193.6 AEO62325.1 - 2.9e-79 266.1 26.0 3.9e-79 265.7 18.0 1.2 1 0 0 1 1 1 1 INO80 complex subunit Ies4 TLP-20 PF06088.6 AEO62325.1 - 1.3 8.7 4.1 4.5 6.9 0.3 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CLTH PF10607.4 AEO62326.1 - 7.5e-37 126.2 0.0 1.1e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 AEO62326.1 - 1.8e-19 70.0 0.0 2.8e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 AEO62326.1 - 8.6e-06 25.3 0.3 2e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 LisH DUF2731 PF10806.3 AEO62327.1 - 6.3e-05 23.2 0.1 0.00038 20.7 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2731) GST_C_3 PF14497.1 AEO62327.1 - 0.00035 21.0 0.0 0.00058 20.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 AEO62327.1 - 0.0005 19.8 0.1 0.0011 18.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 AEO62327.1 - 0.027 14.7 0.0 0.067 13.4 0.0 1.7 1 1 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Pkinase PF00069.20 AEO62328.1 - 9.5e-25 87.2 0.0 3.3e-24 85.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO62328.1 - 1.7e-06 27.2 0.1 4.5e-06 25.9 0.0 1.7 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 AEO62328.1 - 0.0032 16.5 0.0 0.015 14.3 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcoEI_R_C PF08463.5 AEO62328.1 - 0.073 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 EcoEI R protein C-terminal adh_short PF00106.20 AEO62330.1 - 7e-22 78.1 3.8 7.1e-18 65.0 0.9 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 AEO62330.1 - 6.4e-21 75.2 0.0 5.7e-15 55.7 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO62330.1 - 2e-09 37.3 0.6 4.1e-09 36.3 0.2 1.7 2 0 0 2 2 2 1 KR domain OTU PF02338.14 AEO62331.1 - 4.6e-15 56.2 0.0 3.3e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 OTU-like cysteine protease Peptidase_C65 PF10275.4 AEO62331.1 - 0.00018 20.9 0.0 0.0032 16.8 0.0 2.0 2 0 0 2 2 2 1 Peptidase C65 Otubain Mcp5_PH PF12814.2 AEO62332.1 - 2.3e-47 159.9 0.0 4.6e-47 158.9 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology YkyA PF10368.4 AEO62332.1 - 0.033 13.5 7.9 0.055 12.7 5.5 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein TPR_MLP1_2 PF07926.7 AEO62332.1 - 0.56 9.9 23.1 13 5.5 15.7 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_23 PF13476.1 AEO62332.1 - 0.72 10.1 6.0 1.6 9.0 4.1 1.5 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 AEO62332.1 - 2.7 7.1 14.9 5.1 6.2 10.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Oxysterol_BP PF01237.13 AEO62332.1 - 3.1 6.2 6.7 5.2 5.4 4.7 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein NmrA PF05368.8 AEO62333.1 - 8.8e-11 41.4 0.0 1.3e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO62333.1 - 3.7e-08 33.5 0.6 6.2e-08 32.8 0.4 1.3 1 0 0 1 1 1 1 NADH(P)-binding Serglycin PF04360.7 AEO62334.1 - 0.28 10.9 1.5 0.44 10.2 1.1 1.3 1 0 0 1 1 1 0 Serglycin HAD_2 PF13419.1 AEO62335.1 - 3.1e-29 102.4 0.2 2.3e-28 99.6 0.1 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AEO62335.1 - 8.3e-11 42.6 0.1 6.1e-10 39.8 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO62335.1 - 6.2e-07 29.0 0.0 1.4e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Ras PF00071.17 AEO62336.1 - 3.3e-33 114.3 0.0 7.5e-33 113.2 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 AEO62336.1 - 5.8e-08 33.2 0.0 1.2e-05 25.8 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein Ser_hydrolase PF06821.8 AEO62336.1 - 0.054 13.0 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Opy2 PF09463.5 AEO62337.1 - 0.0028 17.6 15.4 0.0047 16.9 10.7 1.4 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.15 AEO62337.1 - 0.015 14.9 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain TPR_12 PF13424.1 AEO62338.1 - 0.023 14.5 0.2 0.042 13.7 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO62338.1 - 0.43 11.3 1.9 6.7 7.6 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Chitin_synth_1 PF01644.12 AEO62339.1 - 1.4e-70 236.3 0.0 2e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 AEO62339.1 - 1.7e-26 92.7 0.1 3.3e-22 78.5 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 AEO62339.1 - 1.7e-26 91.6 0.1 3.2e-26 90.8 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 AEO62339.1 - 3.2e-09 36.7 12.5 3.2e-09 36.7 4.9 3.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AEO62339.1 - 5.7e-09 36.1 0.0 3.5e-08 33.5 0.0 2.2 3 0 0 3 3 3 1 Glycosyltransferase like family 2 UQ_con PF00179.21 AEO62340.1 - 6.2e-35 119.6 0.0 7.9e-35 119.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO62340.1 - 0.012 15.3 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B IlvN PF07991.7 AEO62341.1 - 6.2e-47 159.0 0.0 9.1e-47 158.4 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 AEO62341.1 - 5.8e-46 156.0 0.0 8.8e-46 155.4 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 AEO62341.1 - 0.055 13.8 0.0 0.18 12.2 0.0 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 AEO62341.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IDO PF01231.13 AEO62342.1 - 8.3e-35 120.0 0.0 1.8e-18 66.1 0.0 2.2 1 1 1 2 2 2 2 Indoleamine 2,3-dioxygenase SSP160 PF06933.6 AEO62342.1 - 0.016 13.2 6.1 0.021 12.8 4.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.6 AEO62342.1 - 2.6 5.8 5.5 3.6 5.3 3.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SpoU_methylase PF00588.14 AEO62344.1 - 7.5e-29 100.4 0.0 1.4e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 AEO62344.1 - 3.4e-08 33.5 0.0 9.3e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Kelch_5 PF13854.1 AEO62344.1 - 0.03 14.2 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 Kelch motif zf-PHD-like PF15446.1 AEO62345.1 - 1.9e-73 245.4 13.3 3.3e-73 244.6 9.2 1.4 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 AEO62345.1 - 3.3e-54 183.7 0.0 4.9e-54 183.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO62345.1 - 3.8e-14 52.3 0.0 1.1e-13 50.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 AEO62345.1 - 4e-09 35.7 0.8 1e-08 34.4 0.6 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 AEO62345.1 - 4.9e-05 22.9 4.2 0.009 15.6 0.8 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 AEO62345.1 - 0.00011 21.7 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.24 AEO62345.1 - 0.00083 19.0 6.0 0.00083 19.0 4.2 3.5 3 1 0 3 3 3 1 PHD-finger AAA_22 PF13401.1 AEO62345.1 - 0.022 14.9 0.0 0.095 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain malic PF00390.14 AEO62345.1 - 0.56 9.7 1.1 1.3 8.5 0.8 1.5 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain PHD_2 PF13831.1 AEO62345.1 - 1.2 8.4 13.2 0.061 12.6 1.4 3.6 3 0 0 3 3 3 0 PHD-finger PCI PF01399.22 AEO62347.1 - 0.016 15.5 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 PCI domain Rep_fac-A_C PF08646.5 AEO62348.1 - 3.1e-57 192.3 4.0 1.2e-54 184.0 0.8 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 AEO62348.1 - 6.6e-22 77.2 0.0 1.4e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 AEO62348.1 - 3e-17 62.2 2.2 1.5e-12 47.1 0.0 4.3 4 1 1 5 5 5 2 OB-fold nucleic acid binding domain DUF223 PF02721.9 AEO62348.1 - 0.015 15.3 0.0 0.061 13.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF223 zf-like PF04071.7 AEO62348.1 - 0.022 14.4 0.2 0.056 13.1 0.2 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain DUF3999 PF13163.1 AEO62348.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) Amidohydro_2 PF04909.9 AEO62349.1 - 1e-21 77.7 0.2 1.2e-21 77.4 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase DUF3099 PF11298.3 AEO62349.1 - 0.14 11.9 0.6 0.29 10.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) Cyt-b5 PF00173.23 AEO62351.1 - 6.8e-22 77.0 0.3 7.6e-22 76.9 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YqzH PF14164.1 AEO62351.1 - 0.014 15.3 0.5 0.21 11.5 0.2 2.2 2 0 0 2 2 2 0 YqzH-like protein SUR7 PF06687.7 AEO62353.1 - 9.9e-34 116.7 17.7 1.2e-33 116.4 12.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family CBM_20 PF00686.14 AEO62354.1 - 0.0039 16.7 0.1 0.0069 15.9 0.1 1.4 1 0 0 1 1 1 1 Starch binding domain HD PF01966.17 AEO62360.1 - 0.0031 17.5 3.8 0.011 15.7 2.1 2.3 2 1 0 2 2 2 1 HD domain Cyclase_polyket PF04673.7 AEO62360.1 - 0.01 15.8 0.4 0.028 14.4 0.3 1.8 1 0 0 1 1 1 0 Polyketide synthesis cyclase zf-U1 PF06220.7 AEO62363.1 - 4.9e-19 67.5 4.7 6.6e-19 67.1 3.2 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 AEO62363.1 - 0.01 15.9 3.8 0.046 13.8 2.7 2.0 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 AEO62363.1 - 0.032 14.0 0.1 0.033 13.9 0.1 1.0 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) EMP24_GP25L PF01105.19 AEO62364.1 - 4.3e-42 143.8 0.0 5.1e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4583 PF15190.1 AEO62364.1 - 0.068 12.8 0.2 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4583) DUF4337 PF14235.1 AEO62364.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Sdh5 PF03937.11 AEO62365.1 - 2.7e-22 78.2 0.2 5.7e-22 77.1 0.2 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase MIS13 PF08202.6 AEO62366.1 - 1.9e-65 220.9 0.0 3.9e-65 219.8 0.0 1.5 2 0 0 2 2 2 1 Mis12-Mtw1 protein family Pox_Ag35 PF03286.9 AEO62366.1 - 0.086 12.3 5.2 0.17 11.4 3.6 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC27 PF09507.5 AEO62366.1 - 8.2 5.5 14.4 12 4.9 10.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Aft1_HRA PF11786.3 AEO62367.1 - 2.7e-31 107.6 9.6 2.7e-31 107.6 6.7 2.8 3 0 0 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.3 AEO62367.1 - 7.5e-21 74.9 6.6 7.5e-21 74.9 4.6 3.8 5 0 0 5 5 5 1 Aft1 HRR domain Aft1_OSA PF11785.3 AEO62367.1 - 8.7e-18 64.5 11.0 8.7e-18 64.5 7.6 4.3 5 1 1 6 6 6 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 AEO62367.1 - 2.6e-12 46.5 8.4 4.7e-12 45.6 5.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AEO62367.1 - 3.6e-05 23.4 10.0 3.6e-05 23.4 6.9 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 AEO62367.1 - 0.0095 16.2 4.1 0.0095 16.2 2.8 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor Macoilin PF09726.4 AEO62367.1 - 0.02 13.2 10.4 0.028 12.7 7.2 1.1 1 0 0 1 1 1 0 Transmembrane protein RTBV_P46 PF06216.6 AEO62367.1 - 0.23 10.2 0.6 0.3 9.8 0.4 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Phlebovirus_NSM PF07246.6 AEO62367.1 - 2 7.5 4.6 2.8 7.0 3.2 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M GST_C_2 PF13410.1 AEO62369.1 - 3.9e-06 26.6 1.6 8.3e-06 25.6 1.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AEO62369.1 - 0.06 13.3 0.0 0.27 11.2 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fork_head PF00250.13 AEO62370.1 - 1.7e-12 47.2 0.0 3e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 AEO62370.1 - 0.00038 20.5 0.0 0.00071 19.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain Dicty_REP PF05086.7 AEO62370.1 - 1.2 6.8 6.5 1.6 6.3 4.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein 5TM-5TMR_LYT PF07694.7 AEO62371.1 - 0.0044 16.3 1.5 0.0044 16.3 1.1 1.8 2 0 0 2 2 2 1 5TMR of 5TMR-LYT Ammonium_transp PF00909.16 AEO62371.1 - 0.2 10.1 5.8 0.042 12.3 0.3 2.1 1 1 1 2 2 2 0 Ammonium Transporter Family Spore_YabQ PF09578.5 AEO62372.1 - 1.8 8.5 4.8 0.95 9.4 0.3 2.7 4 0 0 4 4 4 0 Spore cortex protein YabQ (Spore_YabQ) SUR7 PF06687.7 AEO62373.1 - 1.1e-26 93.7 11.5 1.5e-26 93.2 8.0 1.3 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 AEO62373.1 - 2.4e-05 24.0 3.5 2.4e-05 24.0 2.4 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Trp_oprn_chp PF09534.5 AEO62373.1 - 0.0065 16.1 6.8 0.016 14.7 4.3 1.6 1 1 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Git3_C PF11970.3 AEO62373.1 - 0.86 9.4 4.2 3.9 7.3 0.4 2.8 2 1 1 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term DC_STAMP PF07782.8 AEO62373.1 - 1.4 8.5 5.3 0.59 9.7 1.0 2.2 1 1 1 2 2 2 0 DC-STAMP-like protein DUF2207 PF09972.4 AEO62373.1 - 1.8 7.0 3.5 2.7 6.4 2.0 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2802 PF10975.3 AEO62376.1 - 0.075 12.7 0.7 0.16 11.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) TRP PF06011.7 AEO62377.1 - 1.9e-151 504.5 31.2 2.4e-151 504.2 21.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 AEO62377.1 - 4.3e-42 143.5 0.8 7e-42 142.8 0.6 1.4 1 0 0 1 1 1 1 ML-like domain DUF3433 PF11915.3 AEO62378.1 - 1.6e-47 159.6 16.5 1.1e-27 96.0 0.8 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Pho86 PF11124.3 AEO62378.1 - 0.093 11.7 0.1 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Miro PF08477.8 AEO62379.1 - 4.4e-07 30.4 0.2 3.3e-05 24.3 0.1 2.8 2 1 0 2 2 2 1 Miro-like protein Ras PF00071.17 AEO62379.1 - 7.1e-07 28.7 0.0 0.0022 17.4 0.0 3.1 3 0 0 3 3 3 2 Ras family G-alpha PF00503.15 AEO62379.1 - 0.033 12.9 0.1 0.052 12.2 0.1 1.2 1 0 0 1 1 1 0 G-protein alpha subunit TILa PF12714.2 AEO62379.1 - 0.036 13.8 1.2 0.088 12.5 0.8 1.6 1 0 0 1 1 1 0 TILa domain AAA_19 PF13245.1 AEO62379.1 - 0.043 13.5 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 AEO62379.1 - 0.049 13.7 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AEO62379.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 AEO62379.1 - 0.089 12.4 0.1 0.34 10.5 0.1 1.9 1 1 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 AEO62379.1 - 0.19 11.6 3.0 0.22 11.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 AEO62379.1 - 0.2 10.8 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Peptidase_M48 PF01435.13 AEO62380.1 - 1.6e-38 132.5 0.0 2.4e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 SKG6 PF08693.5 AEO62382.1 - 8.5e-05 21.7 2.1 0.00015 21.0 1.4 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.7 AEO62382.1 - 0.043 13.2 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor LT-IIB PF06453.6 AEO62382.1 - 0.077 12.6 0.1 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) bZIP_1 PF00170.16 AEO62383.1 - 9.5e-08 31.8 5.4 9.5e-08 31.8 3.8 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 AEO62383.1 - 2.4e-05 24.0 6.7 2.4e-05 24.0 4.7 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 AEO62383.1 - 0.0051 17.0 8.4 0.0051 17.0 5.9 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor GAS PF13851.1 AEO62383.1 - 0.037 13.2 3.9 0.053 12.7 2.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.4 AEO62383.1 - 0.081 11.2 2.6 0.097 10.9 1.8 1.0 1 0 0 1 1 1 0 Transmembrane protein BCL9 PF11502.3 AEO62383.1 - 0.098 12.1 0.8 0.2 11.1 0.6 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein IncA PF04156.9 AEO62383.1 - 0.11 12.0 1.9 0.14 11.7 1.3 1.2 1 0 0 1 1 1 0 IncA protein DUF2514 PF10721.4 AEO62383.1 - 0.12 12.0 8.8 0.21 11.2 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Ndc1_Nup PF09531.5 AEO62383.1 - 1.1 7.6 3.7 1.2 7.4 2.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4570 PF15134.1 AEO62383.1 - 2.1 8.2 8.3 1.7 8.5 4.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) TPR_12 PF13424.1 AEO62385.1 - 1.1e-15 57.3 5.3 7.1e-06 25.8 0.0 4.0 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 AEO62385.1 - 1.2e-10 40.5 4.6 0.004 16.6 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 AEO62385.1 - 1.1e-09 37.7 4.4 0.009 15.6 0.0 3.7 3 0 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 AEO62385.1 - 1.3e-09 37.2 4.2 9.5e-05 22.0 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 AEO62385.1 - 1.2e-08 34.1 3.5 0.089 12.6 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 AEO62385.1 - 2.6e-07 30.3 5.7 3.1e-05 23.7 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 AEO62385.1 - 0.00023 20.6 4.5 0.25 11.1 0.0 4.1 4 1 1 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 AEO62385.1 - 0.00088 19.3 0.5 0.12 12.4 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 AEO62385.1 - 0.0057 17.0 1.9 0.61 10.6 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 AEO62385.1 - 0.019 15.3 0.0 0.1 13.1 0.0 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 AEO62385.1 - 0.025 15.2 5.8 0.12 13.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 AEO62385.1 - 0.076 13.3 0.4 24 5.3 0.1 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO62385.1 - 0.14 12.8 10.3 1.2 9.9 0.1 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Cyt-b5 PF00173.23 AEO62386.1 - 5.5e-16 58.1 0.0 6.4e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.27 AEO62387.1 - 1.5e-06 27.8 5.7 0.00073 19.3 0.0 5.0 6 0 0 6 6 6 2 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 AEO62387.1 - 0.00089 17.6 0.3 0.0017 16.7 0.2 1.5 1 0 0 1 1 1 1 Cytochrome D1 heme domain DUF230 PF03003.11 AEO62388.1 - 0.078 12.5 5.2 0.081 12.4 3.6 1.1 1 0 0 1 1 1 0 Poxvirus proteins of unknown function Evr1_Alr PF04777.8 AEO62388.1 - 0.52 10.2 4.5 0.46 10.4 2.3 1.5 1 1 1 2 2 2 0 Erv1 / Alr family zf-C3HC4_2 PF13923.1 AEO62388.1 - 3.1 7.9 10.0 12 5.9 3.7 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.1 AEO62389.1 - 0.00088 19.4 10.5 0.0037 17.4 2.5 7.4 9 0 0 9 9 9 4 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO62389.1 - 0.0012 19.0 5.5 0.0012 19.0 3.8 6.5 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 AEO62389.1 - 0.024 14.7 0.8 0.024 14.7 0.5 5.9 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 AEO62391.1 - 0.2 12.0 0.5 41 4.8 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger PPR_2 PF13041.1 AEO62393.1 - 9.2e-24 83.1 0.1 4.2e-10 39.4 0.0 5.5 5 1 1 6 6 6 3 PPR repeat family PPR_3 PF13812.1 AEO62393.1 - 1.8e-16 58.9 3.7 0.0012 18.9 0.0 7.1 9 0 0 9 9 9 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 AEO62393.1 - 8e-12 44.4 0.0 0.0067 15.8 0.0 5.7 6 0 0 6 6 6 4 PPR repeat PPR PF01535.15 AEO62393.1 - 1.8e-10 40.0 6.1 0.01 15.7 0.0 6.6 8 0 0 8 8 8 3 PPR repeat cwf18 PF08315.7 AEO62394.1 - 2.8e-36 124.8 2.4 2.8e-36 124.8 1.6 2.0 2 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor zf-CCHC_3 PF13917.1 AEO62395.1 - 7.2e-19 67.2 1.8 1e-18 66.7 1.2 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 AEO62395.1 - 0.00023 20.6 3.4 0.00037 19.9 2.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 AEO62395.1 - 0.00079 19.2 1.6 0.0011 18.8 1.1 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 AEO62395.1 - 0.1 12.0 0.3 0.23 10.9 0.2 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger SUZ PF12752.2 AEO62396.1 - 8.3e-16 58.2 3.1 8.3e-16 58.2 2.1 3.7 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 AEO62396.1 - 7.8e-08 31.8 0.1 1.5e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 R3H domain Glyco_transf_8 PF01501.15 AEO62396.1 - 0.32 10.3 0.0 0.63 9.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 8 MitMem_reg PF13012.1 AEO62397.1 - 5.3e-16 58.7 0.1 8.1e-16 58.1 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 AEO62397.1 - 1.8e-15 56.6 0.0 3.3e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GRP PF07172.6 AEO62397.1 - 0.25 11.8 17.6 0.51 10.8 12.2 1.5 1 0 0 1 1 1 0 Glycine rich protein family DUF1253 PF06862.7 AEO62398.1 - 1.4e-166 554.3 0.0 1.9e-166 553.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Ribosomal_L17 PF01196.14 AEO62399.1 - 2.3e-31 108.2 0.0 4.2e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 ATP-synt_B PF00430.13 AEO62399.1 - 0.015 15.0 0.2 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) GTSE1_N PF15259.1 AEO62399.1 - 0.044 13.7 0.7 7.2 6.5 0.0 2.2 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 Transposase_24 PF03004.9 AEO62399.1 - 0.07 13.0 2.7 0.079 12.8 0.4 1.9 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) SR-25 PF10500.4 AEO62399.1 - 0.25 10.7 10.5 0.055 12.9 4.5 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Nitro_FeMo-Co PF02579.12 AEO62400.1 - 0.15 12.1 7.5 0.14 12.2 4.2 1.7 1 1 1 2 2 2 0 Dinitrogenase iron-molybdenum cofactor MT0933_antitox PF14013.1 AEO62400.1 - 0.87 9.7 10.9 1.8 8.7 5.6 2.6 2 1 1 3 3 3 0 MT0933-like antitoxin protein DUF883 PF05957.8 AEO62400.1 - 9.6 6.6 18.3 0.63 10.4 3.9 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Acyl_transf_3 PF01757.17 AEO62401.1 - 5.2e-52 176.7 28.8 6.9e-52 176.3 20.0 1.2 1 0 0 1 1 1 1 Acyltransferase family ALAD PF00490.16 AEO62402.1 - 2.2e-118 394.8 0.0 2.5e-118 394.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Defensin_big PF14862.1 AEO62403.1 - 0.022 14.8 1.4 0.053 13.6 0.0 2.1 2 0 0 2 2 2 0 Big defensin Y_phosphatase3 PF13350.1 AEO62404.1 - 6.6e-34 117.5 0.0 8.7e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 AEO62404.1 - 1.7e-12 47.2 0.0 7.5e-12 45.1 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 AEO62404.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 AEO62404.1 - 0.06 12.7 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 AEO62404.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Pkinase PF00069.20 AEO62405.1 - 2.9e-31 108.5 0.0 6.3e-31 107.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO62405.1 - 3.9e-05 22.8 2.5 0.088 11.8 0.0 3.4 4 0 0 4 4 4 3 Protein tyrosine kinase Ribosomal_S4 PF00163.14 AEO62408.1 - 4.1e-12 46.3 4.2 6.9e-12 45.5 2.6 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 AEO62408.1 - 6.2e-12 44.7 0.1 2.1e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 S4 domain Herpes_LAMP2 PF06126.6 AEO62408.1 - 0.045 12.1 0.4 0.051 11.9 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Ribosomal_S18 PF01084.15 AEO62409.1 - 4e-13 49.0 0.0 9.7e-13 47.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 PPR_3 PF13812.1 AEO62410.1 - 2.6e-07 30.3 2.8 0.0014 18.6 0.0 6.0 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 AEO62410.1 - 0.0002 21.1 0.0 29 4.9 0.0 5.4 5 0 0 5 5 5 2 PPR repeat FTA4 PF13093.1 AEO62411.1 - 2.1e-61 207.0 0.0 2.5e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Peptidase_C2 PF00648.16 AEO62412.1 - 4.8e-58 196.4 1.9 4.6e-38 130.9 0.4 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease MIP-T3 PF10243.4 AEO62412.1 - 4.2 5.7 40.9 6.7 5.0 28.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ArfGap PF01412.13 AEO62413.1 - 6.8e-21 74.2 0.2 1.3e-20 73.3 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 AEO62413.1 - 5.8e-05 22.7 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain APH PF01636.18 AEO62414.1 - 0.00017 21.4 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Methyltransf_23 PF13489.1 AEO62416.1 - 1e-17 64.3 0.0 1.7e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO62416.1 - 7.5e-09 36.1 0.0 1.1e-07 32.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO62416.1 - 1.2e-07 32.1 0.0 5e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO62416.1 - 1.6e-07 31.0 0.0 1.1e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO62416.1 - 1.2e-05 25.6 0.0 2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO62416.1 - 9.8e-05 22.6 0.0 0.0007 19.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO62416.1 - 0.0015 17.6 0.0 0.013 14.5 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AEO62416.1 - 0.002 18.1 0.0 0.015 15.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO62416.1 - 0.018 14.4 0.0 0.28 10.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 AEO62416.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 AEO62416.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Pyridoxal_deC PF00282.14 AEO62417.1 - 2e-27 95.5 0.0 2.6e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 AEO62417.1 - 0.0098 15.0 0.1 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 AEO62417.1 - 0.025 13.5 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II B5 PF03484.10 AEO62417.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase B5 domain DUF2462 PF09495.5 AEO62418.1 - 2.5e-09 37.7 13.4 3.2e-09 37.3 9.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) ThiF PF00899.16 AEO62419.1 - 3e-29 101.5 0.0 5.7e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 AEO62419.1 - 0.012 15.7 0.0 0.048 13.7 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase dCMP_cyt_deam_1 PF00383.17 AEO62420.1 - 1.3e-26 92.2 1.5 1.9e-26 91.6 1.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_18 PF13238.1 AEO62420.1 - 9.2e-05 22.7 0.1 0.00068 19.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO62420.1 - 0.00022 22.0 0.0 0.00067 20.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain PMP1_2 PF08114.6 AEO62421.1 - 0.0076 15.7 1.3 0.0097 15.3 0.9 1.2 1 0 0 1 1 1 1 ATPase proteolipid family SP_C-Propep PF08999.5 AEO62421.1 - 0.17 11.3 0.5 0.23 10.9 0.4 1.2 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide TMEMspv1-c74-12 PF11044.3 AEO62421.1 - 0.41 10.2 2.2 0.57 9.7 1.5 1.2 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Glyco_hydro_61 PF03443.9 AEO62422.1 - 4.9e-66 222.6 0.3 6.3e-66 222.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Wzt_C PF14524.1 AEO62422.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Wzt C-terminal domain Bile_Hydr_Trans PF04775.9 AEO62422.1 - 0.12 12.0 0.0 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region 2Fe-2S_thioredx PF01257.14 AEO62423.1 - 4.8e-60 201.3 0.1 6e-60 201.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Kelch_3 PF13415.1 AEO62424.1 - 2.9e-24 84.5 23.8 4.4e-08 33.0 0.2 7.8 7 2 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.1 AEO62424.1 - 8.6e-20 70.2 5.8 4.5e-05 23.3 0.0 7.0 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.1 AEO62424.1 - 9.1e-20 69.9 3.2 2.1e-06 27.6 0.0 6.0 5 1 1 6 6 6 3 Kelch motif Kelch_4 PF13418.1 AEO62424.1 - 2.9e-18 65.3 16.2 1.6e-05 24.5 0.0 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.20 AEO62424.1 - 1e-16 60.1 1.2 1.3e-05 24.6 0.0 5.2 5 1 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 AEO62424.1 - 4.8e-15 54.6 5.4 0.00029 20.4 0.2 6.0 5 1 0 5 5 5 5 Kelch motif Ceramidase_alk PF04734.8 AEO62425.1 - 9.3e-281 932.5 0.0 1.1e-280 932.4 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase BCAS2 PF05700.6 AEO62426.1 - 1.3e-39 135.9 0.0 1.9e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF1822 PF08852.6 AEO62426.1 - 0.087 11.6 0.8 0.11 11.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) TMF_TATA_bd PF12325.3 AEO62426.1 - 0.17 11.6 1.7 0.38 10.5 1.2 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding cNMP_binding PF00027.24 AEO62427.1 - 3.5e-44 148.5 0.0 1.1e-22 79.6 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain GXGXG PF01493.14 AEO62427.1 - 0.11 11.4 0.0 0.64 8.9 0.0 2.0 2 0 0 2 2 2 0 GXGXG motif CDC50 PF03381.10 AEO62428.1 - 1.5e-91 306.4 0.2 1.8e-91 306.1 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SPT16 PF08644.6 AEO62429.1 - 3.9e-58 195.6 0.6 1.2e-57 194.0 0.1 2.2 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 AEO62429.1 - 4.6e-53 179.0 0.1 1.1e-52 177.8 0.1 1.7 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 AEO62429.1 - 1.2e-24 87.0 0.0 2.3e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 AEO62429.1 - 1.8e-21 75.9 0.0 4.5e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like GATA PF00320.22 AEO62431.1 - 1.1e-15 56.6 3.4 1.8e-15 55.9 2.3 1.3 1 0 0 1 1 1 1 GATA zinc finger GCS PF03074.11 AEO62432.1 - 1.7e-151 504.4 0.0 7.8e-123 410.1 0.0 2.2 1 1 0 2 2 2 2 Glutamate-cysteine ligase Glycophorin_A PF01102.13 AEO62433.1 - 0.0047 16.6 7.2 0.0079 15.9 1.3 3.2 2 0 0 2 2 2 1 Glycophorin A CFEM PF05730.6 AEO62433.1 - 0.34 10.7 5.1 0.42 10.4 2.9 1.6 1 1 0 1 1 1 0 CFEM domain DEAD PF00270.24 AEO62434.1 - 6.3e-34 116.9 0.1 6e-33 113.7 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO62434.1 - 2.2e-22 78.7 0.0 4.1e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 AEO62434.1 - 0.0012 18.5 0.1 0.087 12.5 0.0 2.6 2 1 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 AEO62434.1 - 0.0028 17.2 0.0 0.0068 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain Helicase_C_2 PF13307.1 AEO62434.1 - 0.0031 17.4 0.0 0.0088 16.0 0.0 1.7 2 0 0 2 2 2 1 Helicase C-terminal domain CMS1 PF14617.1 AEO62434.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 AEO62434.1 - 0.027 14.6 0.5 0.78 9.8 0.2 2.8 2 1 0 2 2 2 0 AAA domain FCH PF00611.18 AEO62435.1 - 3.5e-23 81.5 4.4 5.4e-23 80.9 0.0 3.3 3 1 1 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 AEO62435.1 - 4.7e-21 74.0 0.3 3.3e-12 45.7 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.17 AEO62435.1 - 1.4e-14 53.5 5.6 2.2e-14 52.9 3.9 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.23 AEO62435.1 - 2.4e-13 49.2 0.0 1.7e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.6 AEO62435.1 - 0.0014 18.7 0.1 0.064 13.4 0.0 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain Allexi_40kDa PF05549.6 AEO62435.1 - 0.066 12.5 1.4 0.27 10.5 0.0 2.4 3 0 0 3 3 3 0 Allexivirus 40kDa protein C1_2 PF03107.11 AEO62435.1 - 0.58 10.3 7.8 0.98 9.5 5.4 1.3 1 0 0 1 1 1 0 C1 domain Glyco_hydro_72 PF03198.9 AEO62436.1 - 2e-119 398.2 1.8 2.6e-119 397.8 1.3 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 AEO62436.1 - 8e-06 25.2 1.1 9.5e-05 21.7 0.8 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GAF_2 PF13185.1 AEO62437.1 - 4.6e-08 33.6 0.2 9e-08 32.7 0.1 1.5 1 1 0 2 2 2 1 GAF domain GAF PF01590.21 AEO62437.1 - 0.00099 19.2 0.4 0.0013 18.8 0.3 1.4 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 AEO62437.1 - 0.0048 17.0 0.1 0.024 14.7 0.1 2.1 1 1 0 1 1 1 1 GAF domain Coatomer_E PF04733.9 AEO62439.1 - 4e-60 203.4 7.9 4.6e-60 203.2 5.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_1 PF00515.23 AEO62439.1 - 6.4e-06 25.5 1.2 0.019 14.5 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO62439.1 - 7.8e-05 23.2 1.3 7.8e-05 23.2 0.9 5.8 3 1 4 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 AEO62439.1 - 8.6e-05 22.8 1.1 8.6e-05 22.8 0.8 6.6 2 1 6 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 AEO62439.1 - 0.00013 22.1 12.1 0.00047 20.4 1.4 4.6 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 AEO62439.1 - 0.0003 20.3 0.6 0.017 14.8 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 AEO62439.1 - 0.00076 19.2 0.0 0.00076 19.2 0.0 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 AEO62439.1 - 0.0012 18.4 12.5 0.0015 18.1 0.0 4.6 2 1 2 4 4 4 1 TPR repeat Apc3 PF12895.2 AEO62439.1 - 0.0016 18.5 10.0 0.98 9.5 0.1 3.6 1 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 AEO62439.1 - 0.0041 17.2 2.9 2 8.7 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 AEO62439.1 - 0.0066 16.1 13.5 0.16 11.8 0.1 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 AEO62439.1 - 0.0083 16.0 21.1 0.075 12.9 0.2 4.5 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 AEO62439.1 - 0.014 15.7 10.0 0.26 11.8 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Type_III_YscG PF09477.5 AEO62439.1 - 0.017 15.1 12.6 0.71 9.9 1.3 3.8 1 1 3 4 4 4 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Smr PF01713.16 AEO62439.1 - 0.024 14.8 0.3 0.98 9.6 0.0 2.5 2 0 0 2 2 2 0 Smr domain TPR_4 PF07721.9 AEO62439.1 - 0.032 14.6 1.6 0.032 14.6 1.1 7.5 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_9 PF13371.1 AEO62439.1 - 0.054 13.3 0.6 0.054 13.3 0.4 4.8 2 2 3 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AEO62439.1 - 0.058 13.2 0.9 0.35 10.7 0.1 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 AEO62439.1 - 7.3 6.6 23.2 2.9 7.9 0.2 5.6 5 1 2 7 7 7 0 Tetratricopeptide repeat MFS_1 PF07690.11 AEO62440.1 - 1.1e-27 96.6 58.5 1.1e-27 96.6 40.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 AEO62441.1 - 7.8e-10 38.0 0.0 1.4e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PS_Dcarbxylase PF02666.10 AEO62442.1 - 1.5e-52 177.8 0.0 2.3e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 AEO62442.1 - 1e-35 121.4 0.1 1.1e-17 63.6 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 AEO62442.1 - 0.00063 19.8 0.1 0.0017 18.4 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 AEO62442.1 - 0.0019 17.3 0.0 0.0053 15.9 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 AEO62442.1 - 0.01 15.6 0.0 0.038 13.8 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.1 AEO62442.1 - 0.033 13.5 0.0 0.093 12.1 0.0 1.8 1 0 0 1 1 1 0 EF hand SLY PF12485.3 AEO62443.1 - 0.034 14.3 0.5 0.047 13.9 0.3 1.2 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein PNRC PF15365.1 AEO62443.1 - 2.4 8.2 8.6 3.7 7.6 6.0 1.4 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator DUF3405 PF11885.3 AEO62445.1 - 5.2e-180 598.9 1.2 9.2e-180 598.1 0.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) LIM PF00412.17 AEO62446.1 - 5.3e-22 77.6 12.5 7.1e-12 45.2 2.3 2.3 2 0 0 2 2 2 2 LIM domain C1_3 PF07649.7 AEO62446.1 - 0.78 9.8 17.1 0.85 9.7 0.6 4.1 4 0 0 4 4 4 0 C1-like domain WRC PF08879.5 AEO62446.1 - 1.7 8.3 5.5 0.76 9.4 0.1 2.6 3 0 0 3 3 3 0 WRC NAD_binding_5 PF07994.7 AEO62447.1 - 3.1e-114 381.4 0.1 3.7e-114 381.1 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 AEO62447.1 - 3.3e-45 152.5 0.3 5.6e-45 151.7 0.2 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase AMP-binding PF00501.23 AEO62448.1 - 2.7e-81 273.1 0.0 3.5e-81 272.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO62448.1 - 2.3e-13 50.8 0.2 6.7e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 AEO62450.1 - 1.2e-32 113.0 57.1 3.2e-29 101.7 26.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO62450.1 - 6.5e-22 77.7 23.2 2e-21 76.1 16.0 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DnaJ PF00226.26 AEO62451.1 - 4.5e-15 55.1 0.0 7.1e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pkinase_Tyr PF07714.12 AEO62452.1 - 1e-17 64.1 0.0 3.5e-11 42.6 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 AEO62452.1 - 8.3e-17 61.1 0.0 2.9e-16 59.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 AEO62452.1 - 0.00078 18.5 0.1 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AEO62452.1 - 0.14 11.1 0.0 0.64 8.9 0.0 1.9 1 1 0 1 1 1 0 Kinase-like DUF3632 PF12311.3 AEO62453.1 - 1.9e-10 40.8 0.3 4.2e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) SCP2 PF02036.12 AEO62455.1 - 1.9e-24 85.9 0.3 2.4e-24 85.5 0.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 AEO62455.1 - 4.6e-07 29.8 0.2 5.7e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.1 AEO62455.1 - 0.021 14.2 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 Sterol carrier protein domain Ran_BP1 PF00638.13 AEO62456.1 - 1.6e-12 47.5 0.2 3.4e-11 43.2 0.1 2.3 1 1 0 1 1 1 1 RanBP1 domain ECH PF00378.15 AEO62457.1 - 3.1e-37 128.0 1.0 1.2e-35 122.7 0.7 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family TIM-br_sig_trns PF09370.5 AEO62457.1 - 0.0061 15.6 0.1 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 TIM-barrel signal transduction protein ECH_C PF13766.1 AEO62457.1 - 0.011 15.8 0.1 0.023 14.8 0.1 1.5 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region SAM_2 PF07647.12 AEO62458.1 - 1.7e-14 53.3 0.1 3.2e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 AEO62458.1 - 1e-12 47.3 0.0 1.9e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AEO62458.1 - 1.1e-11 43.9 0.0 2.1e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 AEO62458.1 - 6.6e-08 32.7 0.0 1.5e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 AEO62458.1 - 4.8e-05 23.5 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 AEO62458.1 - 0.00015 21.1 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 AEO62458.1 - 0.0084 16.2 0.1 0.025 14.7 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Gastrin PF00918.12 AEO62458.1 - 0.034 14.9 0.0 0.32 11.7 0.0 2.8 1 0 0 1 1 1 0 Gastrin/cholecystokinin family PH_8 PF15409.1 AEO62458.1 - 0.07 13.2 0.0 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain adh_short PF00106.20 AEO62459.1 - 5.2e-15 55.7 1.9 1.3e-14 54.4 1.3 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO62459.1 - 4.3e-06 26.5 1.1 9.1e-06 25.4 0.8 1.5 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 AEO62459.1 - 0.009 15.7 0.6 0.026 14.2 0.4 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2493 PF10686.4 AEO62459.1 - 0.034 13.6 0.1 0.16 11.5 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) Zn_clus PF00172.13 AEO62460.1 - 9.2e-06 25.4 12.1 1.5e-05 24.7 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nucleopor_Nup85 PF07575.8 AEO62461.1 - 7.5e-13 47.5 0.0 2.5e-11 42.5 0.0 2.6 1 1 0 1 1 1 1 Nup85 Nucleoporin Nic96 PF04097.9 AEO62461.1 - 0.2 9.7 0.5 0.3 9.1 0.0 1.4 2 0 0 2 2 2 0 Nup93/Nic96 DUF952 PF06108.7 AEO62462.1 - 1.3e-23 82.6 0.0 1.6e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) ADH_N PF08240.7 AEO62463.1 - 2.2e-28 98.1 1.4 2.2e-28 98.1 1.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO62463.1 - 1.7e-20 72.8 0.4 3.4e-20 71.9 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.16 AEO62463.1 - 0.011 15.5 2.3 0.2 11.4 1.3 2.3 2 0 0 2 2 2 0 ThiF family UDPG_MGDP_dh_N PF03721.9 AEO62463.1 - 0.13 11.6 1.9 0.23 10.8 1.1 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-AN1 PF01428.11 AEO62464.1 - 5.8e-11 42.0 13.8 8e-11 41.6 9.6 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger HhH-GPD PF00730.20 AEO62465.1 - 3.3e-18 65.9 0.0 5.7e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 AEO62465.1 - 1.2e-06 27.8 0.0 3.2e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF676 PF05057.9 AEO62466.1 - 2.9e-50 170.5 0.0 4e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 AEO62466.1 - 6.6e-07 29.4 0.3 1.8e-06 27.9 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO62466.1 - 6.8e-06 25.9 0.1 6e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family FliJ PF02050.11 AEO62466.1 - 0.027 14.5 0.1 0.064 13.3 0.1 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein PGAP1 PF07819.8 AEO62466.1 - 0.032 13.7 0.0 0.078 12.5 0.0 1.6 1 1 0 1 1 1 0 PGAP1-like protein zf-C3Hc3H PF13891.1 AEO62467.1 - 0.39 10.8 0.1 0.39 10.8 0.1 4.2 3 2 1 4 4 4 0 Potential DNA-binding domain GDPD PF03009.12 AEO62468.1 - 5.3e-26 91.6 0.0 2.8e-24 85.9 0.0 2.1 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Fungal_trans PF04082.13 AEO62469.1 - 9.9e-33 113.0 0.2 2.1e-32 112.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO62469.1 - 9e-09 35.1 14.6 1.9e-08 34.0 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SET PF00856.23 AEO62470.1 - 0.00026 21.3 0.0 0.0036 17.6 0.0 2.3 1 1 0 1 1 1 1 SET domain MMR_HSR1_C PF08438.5 AEO62471.1 - 6.5e-33 113.2 0.0 1.4e-32 112.1 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 AEO62471.1 - 1.1e-18 67.2 0.0 2.5e-18 66.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO62471.1 - 1.6e-08 34.0 0.0 4.7e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AEO62471.1 - 0.0041 16.9 1.5 0.1 12.3 0.2 2.9 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 AEO62471.1 - 0.0085 15.5 0.0 0.51 9.7 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 AEO62471.1 - 0.17 10.9 0.2 0.49 9.4 0.1 1.7 2 0 0 2 2 2 0 AIG1 family Pmp3 PF01679.12 AEO62472.1 - 3.6e-26 90.6 5.1 3.9e-26 90.4 3.5 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 AEO62472.1 - 0.11 12.1 1.1 0.11 12.1 0.7 1.8 2 0 0 2 2 2 0 Conserved TM helix Ribosomal_L22e PF01776.12 AEO62473.1 - 1.5e-46 156.9 0.6 1.8e-46 156.7 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Mito_carr PF00153.22 AEO62474.1 - 6.3e-56 186.0 0.2 2.3e-19 68.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PIG-F PF06699.6 AEO62475.1 - 2.6e-58 197.1 1.9 3.4e-58 196.7 1.3 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Translin PF01997.11 AEO62476.1 - 1.5e-48 165.0 0.0 1.9e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Translin family GMP_synt_C PF00958.17 AEO62476.1 - 0.095 12.4 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 GMP synthase C terminal domain p450 PF00067.17 AEO62477.1 - 1.5e-58 198.4 0.0 2.5e-58 197.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 TPR_12 PF13424.1 AEO62480.1 - 1.2e-80 265.4 5.3 1.1e-17 63.7 0.0 5.0 3 1 3 6 6 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 AEO62480.1 - 2.8e-55 182.7 12.0 1.4e-10 40.7 0.1 7.9 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 AEO62480.1 - 7.9e-34 113.8 0.0 9.5e-05 21.8 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 AEO62480.1 - 5.3e-26 90.0 0.4 3.8e-07 29.6 0.0 4.7 2 1 0 4 4 4 4 TPR repeat TPR_2 PF07719.12 AEO62480.1 - 1e-21 75.0 0.8 0.0039 16.9 0.0 7.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 AEO62480.1 - 1.2e-21 74.7 7.6 0.0022 17.6 0.0 7.5 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 AEO62480.1 - 8.8e-21 72.5 11.8 0.033 14.8 0.1 8.3 4 3 4 8 8 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 AEO62480.1 - 1.5e-18 66.9 3.0 4.1e-05 24.1 0.0 5.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 AEO62480.1 - 4e-18 63.7 0.1 0.24 11.2 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 AEO62480.1 - 3.7e-13 49.6 2.5 0.011 16.0 0.0 5.7 3 3 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 AEO62480.1 - 6.3e-13 47.8 0.2 0.77 10.1 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 AEO62480.1 - 2.3e-11 42.9 0.0 5 7.8 0.0 7.2 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.15 AEO62480.1 - 2.1e-09 36.7 0.4 0.85 9.7 0.0 7.1 7 0 0 7 7 7 1 PPR repeat TPR_6 PF13174.1 AEO62480.1 - 6.6e-07 29.3 8.7 5 7.8 0.1 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat Rab5-bind PF09311.6 AEO62480.1 - 5.2e-06 26.4 0.1 0.11 12.3 0.3 4.1 2 1 1 3 3 3 1 Rabaptin-like protein 14-3-3 PF00244.15 AEO62480.1 - 7.4e-05 21.9 0.1 1.1 8.2 0.0 3.4 2 1 0 3 3 3 1 14-3-3 protein TPR_3 PF07720.7 AEO62480.1 - 0.00011 21.9 0.0 13 5.6 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.1 AEO62480.1 - 0.0077 16.4 2.1 0.0077 16.4 1.5 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger RPN7 PF10602.4 AEO62480.1 - 0.011 15.1 0.2 41 3.5 0.0 4.0 2 2 2 4 4 4 0 26S proteasome subunit RPN7 zf-C2H2 PF00096.21 AEO62480.1 - 0.012 15.9 1.9 0.012 15.9 1.3 3.9 4 0 0 4 4 3 0 Zinc finger, C2H2 type TPR_21 PF09976.4 AEO62480.1 - 0.014 15.3 1.1 36 4.2 0.0 5.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.1 AEO62480.1 - 0.088 12.6 6.8 17 5.3 0.1 5.2 4 1 2 6 6 6 0 Tetratricopeptide repeat DUF629 PF04780.7 AEO62480.1 - 0.2 10.1 0.6 0.35 9.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Snf7 PF03357.16 AEO62481.1 - 2.2e-33 115.0 20.5 2.2e-33 115.0 14.2 2.0 1 1 1 2 2 2 1 Snf7 MutS_III PF05192.13 AEO62481.1 - 0.16 11.7 3.6 0.2 11.4 2.5 1.2 1 0 0 1 1 1 0 MutS domain III Misat_Tub_SegII PF10644.4 AEO62481.1 - 0.24 11.4 3.9 0.71 9.9 2.7 2.1 1 1 0 1 1 1 0 Misato Segment II tubulin-like domain GTPase_Cys_C PF12631.2 AEO62481.1 - 0.34 11.3 2.7 0.43 11.0 0.3 2.3 1 1 1 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Allexi_40kDa PF05549.6 AEO62481.1 - 2.1 7.5 7.7 1.8 7.7 4.4 1.6 1 1 1 2 2 2 0 Allexivirus 40kDa protein IFT57 PF10498.4 AEO62481.1 - 3.7 6.1 16.9 0.9 8.2 6.5 2.2 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 CK2S PF15011.1 AEO62481.1 - 4.1 7.1 10.2 3.3 7.4 0.1 2.5 2 1 1 3 3 3 0 Casein Kinase 2 substrate DUF3138 PF11336.3 AEO62481.1 - 6.5 4.8 6.5 2.7 6.0 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Ten1 PF12658.2 AEO62482.1 - 1.1e-31 109.1 0.0 1.2e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit ICE2 PF08426.5 AEO62486.1 - 2e-148 494.4 16.5 2.3e-148 494.2 11.5 1.0 1 0 0 1 1 1 1 ICE2 AT_hook PF02178.14 AEO62487.1 - 0.011 15.2 50.7 0.14 11.8 1.9 5.1 4 0 0 4 4 4 0 AT hook motif K_channel_TID PF07941.6 AEO62487.1 - 0.015 15.4 6.3 0.015 15.4 4.4 3.3 2 1 1 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain HA2 PF04408.18 AEO62488.1 - 4.3e-21 74.8 0.2 3.1e-20 72.0 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AEO62488.1 - 8.6e-15 54.5 0.0 2.4e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AEO62488.1 - 7.9e-14 51.2 0.1 2.9e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RWD PF05773.17 AEO62488.1 - 3.7e-09 36.4 0.1 8.5e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 AEO62488.1 - 1.2e-08 34.6 0.0 3e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase UBA PF00627.26 AEO62488.1 - 2.9e-06 26.9 1.2 0.0012 18.6 0.0 3.3 3 0 0 3 3 2 1 UBA/TS-N domain AAA_19 PF13245.1 AEO62488.1 - 0.00038 20.1 0.1 0.0014 18.3 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 AEO62488.1 - 0.00062 19.9 0.0 0.0017 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 AEO62488.1 - 0.0027 17.1 0.1 0.0093 15.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain KaiC PF06745.8 AEO62488.1 - 0.019 14.1 0.1 0.036 13.1 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 AEO62488.1 - 0.043 14.1 0.1 0.087 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 AEO62488.1 - 0.051 12.4 0.0 0.096 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.10 AEO62488.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DND1_DSRM PF14709.1 AEO62488.1 - 0.11 12.7 0.0 0.11 12.7 0.0 2.4 3 0 0 3 3 3 0 double strand RNA binding domain from DEAD END PROTEIN 1 Aldo_ket_red PF00248.16 AEO62488.1 - 0.16 10.7 0.0 0.34 9.6 0.0 1.5 1 0 0 1 1 1 0 Aldo/keto reductase family Zot PF05707.7 AEO62488.1 - 0.25 10.7 0.0 0.49 9.8 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Arm PF00514.18 AEO62489.1 - 2.5e-96 312.6 15.6 2.6e-14 52.3 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 AEO62489.1 - 3.3e-27 94.6 0.4 1.6e-11 44.3 0.0 5.7 1 1 3 5 5 5 5 HEAT repeats IBB PF01749.15 AEO62489.1 - 1.6e-23 82.6 1.1 2.8e-23 81.8 0.8 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 AEO62489.1 - 3.4e-23 81.4 10.2 6.5e-10 39.2 0.0 6.3 5 1 2 7 7 7 4 HEAT-like repeat HEAT PF02985.17 AEO62489.1 - 1.6e-22 77.5 2.1 6.9e-07 28.8 0.0 7.3 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.8 AEO62489.1 - 5.3e-11 42.1 0.0 0.0051 15.9 0.0 4.1 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 AEO62489.1 - 8.5e-07 27.6 0.0 6.4e-05 21.4 0.0 2.6 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 AEO62489.1 - 6.6e-05 22.8 0.0 0.99 9.3 0.0 4.5 3 2 0 4 4 4 1 V-ATPase subunit H HEAT_PBS PF03130.11 AEO62489.1 - 0.00021 21.4 1.0 0.4 11.2 0.1 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 AEO62489.1 - 0.0014 17.0 0.3 0.44 8.7 0.0 3.1 3 1 1 4 4 4 2 Proteasome non-ATPase 26S subunit Glycos_trans_3N PF02885.12 AEO62489.1 - 0.11 12.1 0.0 14 5.3 0.0 3.3 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain SURF6 PF04935.7 AEO62489.1 - 2.9 7.1 8.3 4.5 6.4 5.8 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 POT1 PF02765.12 AEO62490.1 - 1.6e-17 63.7 0.0 3.8e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 AEO62490.1 - 0.12 12.1 0.0 2.6 7.9 0.0 2.6 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain STAG PF08514.6 AEO62491.1 - 1.9e-29 101.7 0.6 4.3e-29 100.6 0.4 1.6 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 AEO62491.1 - 6.9e-09 35.8 1.0 0.001 19.3 0.0 3.7 1 1 2 3 3 3 3 HEAT repeats DUF1664 PF07889.7 AEO62491.1 - 0.068 12.9 0.6 9.2 6.0 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) UreD PF01774.12 AEO62492.1 - 4.4e-57 192.9 0.0 5.4e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein RNA_pol_Rpc4 PF05132.9 AEO62493.1 - 2.9e-24 85.5 0.0 2.9e-24 85.5 0.0 3.2 3 1 0 3 3 3 1 RNA polymerase III RPC4 FAD_binding_3 PF01494.14 AEO62494.1 - 2e-14 53.3 0.1 1.6e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 AEO62494.1 - 1.1e-10 41.0 8.2 3.7e-06 26.0 1.4 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 AEO62494.1 - 1.9e-06 27.0 0.7 0.0054 15.6 0.4 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 AEO62494.1 - 2.2e-05 23.1 0.1 7.1e-05 21.4 0.1 1.8 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 AEO62494.1 - 4.6e-05 23.3 0.0 0.00022 21.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO62494.1 - 0.00026 19.9 1.8 0.00048 19.0 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 AEO62494.1 - 0.00067 19.6 0.3 0.0015 18.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AEO62494.1 - 0.00077 19.5 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO62494.1 - 0.0015 18.9 0.2 0.044 14.1 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AEO62494.1 - 0.067 12.0 1.0 0.1 11.4 0.7 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A MFS_1 PF07690.11 AEO62495.1 - 9.2e-31 106.8 43.2 9.2e-31 106.8 30.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 AEO62496.1 - 0.00068 19.5 12.3 0.0012 18.6 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_N PF00134.18 AEO62498.1 - 3.8e-43 146.0 0.4 7e-43 145.2 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AEO62498.1 - 4.7e-31 107.1 0.3 1.9e-30 105.2 0.0 2.2 3 0 0 3 3 3 1 Cyclin, C-terminal domain Mito_carr PF00153.22 AEO62499.1 - 1.2e-73 242.8 1.2 7.3e-26 89.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 AEO62499.1 - 1.7e-16 58.1 0.1 3e-07 29.2 0.0 5.1 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.1 AEO62499.1 - 3.7e-14 51.2 3.5 1.3e-05 24.6 0.0 5.9 6 0 0 6 6 6 3 EF-hand domain EF-hand_7 PF13499.1 AEO62499.1 - 2.3e-13 50.0 3.9 3.3e-06 27.1 0.0 3.9 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_8 PF13833.1 AEO62499.1 - 3e-13 49.1 0.3 0.0097 15.5 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 AEO62499.1 - 2.2e-10 39.4 0.5 8.8e-06 24.8 0.0 4.1 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.2 AEO62499.1 - 0.068 12.9 0.0 0.54 10.0 0.0 2.4 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 AEO62499.1 - 0.087 12.5 0.1 8.6 6.1 0.0 3.3 3 1 0 3 3 3 0 EF hand RNase_E_G PF10150.4 AEO62499.1 - 0.11 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease E/G family PQ-loop PF04193.9 AEO62501.1 - 8.5e-33 111.6 9.5 3.9e-16 58.3 0.4 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF606 PF04657.8 AEO62501.1 - 0.004 17.2 1.2 1.1 9.2 0.2 2.5 3 0 0 3 3 3 2 Protein of unknown function, DUF606 ADH_zinc_N PF00107.21 AEO62502.1 - 4.5e-14 52.0 0.0 7.4e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.11 AEO62503.1 - 4.8e-33 114.3 33.7 4.8e-33 114.3 23.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO62503.1 - 1.1e-05 24.1 19.3 3e-05 22.7 13.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter UNC-93 PF05978.11 AEO62503.1 - 0.012 15.0 2.0 0.012 15.0 1.4 2.2 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 PALP PF00291.20 AEO62504.1 - 6.7e-31 107.6 1.0 7.7e-31 107.4 0.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FIVAR PF07554.8 AEO62504.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised Sugar-binding Domain adh_short PF00106.20 AEO62505.1 - 3.7e-21 75.7 0.3 5.7e-21 75.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO62505.1 - 1.7e-12 47.6 0.0 2.3e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 AEO62505.1 - 9e-07 28.3 0.0 3.7e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 AEO62505.1 - 3.7e-05 23.4 0.4 0.00018 21.2 0.3 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO62505.1 - 0.0027 17.7 0.1 0.0045 17.0 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO62505.1 - 0.0033 16.8 0.0 0.0096 15.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 AEO62505.1 - 0.0068 15.6 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Glyco_trans_4_4 PF13579.1 AEO62505.1 - 0.13 12.3 0.3 0.47 10.5 0.1 2.1 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain ADH_N PF08240.7 AEO62506.1 - 0.00056 19.6 0.1 0.00065 19.4 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain zf-C2H2_4 PF13894.1 AEO62507.1 - 1.3e-05 25.1 10.0 0.23 11.8 0.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO62507.1 - 7.2e-05 22.8 9.4 0.048 14.0 1.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type HALZ PF02183.13 AEO62507.1 - 0.007 16.0 2.2 0.015 15.0 1.5 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper Herpes_BLRF2 PF05812.7 AEO62507.1 - 0.01 15.6 2.9 0.021 14.6 2.0 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein zf-H2C2_2 PF13465.1 AEO62507.1 - 0.012 15.8 10.5 5.9 7.3 1.4 3.6 3 0 0 3 3 3 0 Zinc-finger double domain TMF_DNA_bd PF12329.3 AEO62507.1 - 0.023 14.4 5.8 0.038 13.7 4.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 AEO62507.1 - 0.11 11.5 2.1 0.14 11.1 1.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 EFG_II PF14492.1 AEO62507.1 - 0.12 12.1 0.8 0.25 11.2 0.5 1.5 1 0 0 1 1 1 0 Elongation Factor G, domain II bZIP_2 PF07716.10 AEO62507.1 - 1 9.2 12.5 0.14 12.0 5.5 1.9 2 0 0 2 2 2 0 Basic region leucine zipper Eno-Rase_FAD_bd PF07055.7 AEO62507.1 - 1 9.3 3.7 2.8 7.9 2.6 1.8 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain Methyltransf_11 PF08241.7 AEO62509.1 - 2.3e-17 63.2 0.0 5.8e-17 61.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO62509.1 - 6.4e-13 48.7 0.0 9.4e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO62509.1 - 5.5e-12 45.9 0.0 9.9e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO62509.1 - 7.6e-12 45.7 0.0 1.4e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO62509.1 - 1.1e-10 41.3 0.0 1.7e-10 40.6 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO62509.1 - 1.5e-08 34.6 0.2 2.5e-08 33.9 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO62509.1 - 9e-08 32.5 0.0 1.6e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AEO62509.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 AEO62509.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.17 AEO62510.1 - 3.1e-46 157.8 0.0 4.3e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_18 PF12847.2 AEO62511.1 - 1.1e-08 35.6 0.0 0.0029 18.1 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 AEO62511.1 - 5.5e-06 26.1 0.0 8.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO62511.1 - 0.025 14.1 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 AEO62511.1 - 0.046 13.7 0.0 0.14 12.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 AEO62511.1 - 0.082 13.3 0.1 0.61 10.5 0.2 2.4 2 0 0 2 2 2 0 Methyltransferase domain MetW PF07021.7 AEO62511.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Abhydrolase_5 PF12695.2 AEO62512.1 - 7.3e-08 32.2 0.0 1.4e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO62512.1 - 1.3e-06 28.4 0.6 2.3e-06 27.6 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 AEO62512.1 - 0.0096 15.2 0.0 0.074 12.3 0.0 2.1 1 1 1 2 2 2 1 Dienelactone hydrolase family Oxidored_nitro PF00148.14 AEO62512.1 - 0.05 12.2 0.0 0.39 9.2 0.0 1.9 1 1 1 2 2 2 0 Nitrogenase component 1 type Oxidoreductase DUF218 PF02698.12 AEO62513.1 - 1.1e-07 31.4 0.3 2.9e-06 26.8 0.1 2.3 1 1 0 1 1 1 1 DUF218 domain Mur_ligase_M PF08245.7 AEO62514.1 - 1.6e-06 28.3 0.4 5.8e-06 26.4 0.3 1.9 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 AEO62514.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain LacI PF00356.16 AEO62515.1 - 0.097 12.3 0.2 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family DUF2360 PF10152.4 AEO62515.1 - 0.1 12.8 3.0 1.4 9.2 0.1 2.6 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Pkinase PF00069.20 AEO62516.1 - 1.3e-69 234.2 0.0 2.6e-69 233.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO62516.1 - 1.1e-48 165.5 0.0 1.9e-48 164.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO62516.1 - 0.001 18.1 0.0 0.0024 16.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like MtrA PF04208.9 AEO62516.1 - 0.003 17.0 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit A Ric8 PF10165.4 AEO62516.1 - 0.057 12.2 0.8 5.7 5.6 0.4 2.3 2 0 0 2 2 2 0 Guanine nucleotide exchange factor synembryn DUF2321 PF10083.4 AEO62516.1 - 0.073 12.5 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Kdo PF06293.9 AEO62516.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SoxE PF06525.6 AEO62516.1 - 7.7 5.7 9.1 9.7 5.4 4.2 2.4 3 0 0 3 3 3 0 Sulfocyanin (SoxE) F-box-like PF12937.2 AEO62517.1 - 0.0088 15.7 0.1 0.027 14.1 0.0 1.9 2 0 0 2 2 2 1 F-box-like DUF1191 PF06697.7 AEO62518.1 - 0.018 13.8 1.0 0.027 13.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4131 PF13567.1 AEO62518.1 - 3.7 6.9 11.4 0.13 11.6 2.6 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) ERG4_ERG24 PF01222.12 AEO62519.1 - 1.8e-140 468.3 16.3 2.2e-140 467.9 11.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ATP-synt_C PF00137.16 AEO62520.1 - 5.6e-31 106.2 32.0 1e-18 66.9 9.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 AEO62520.1 - 0.25 10.8 4.5 0.078 12.5 0.7 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A ABA_GPCR PF12430.3 AEO62520.1 - 0.29 10.2 1.4 3 6.9 0.1 2.1 1 1 0 2 2 2 0 Abscisic acid G-protein coupled receptor DUF2970 PF11174.3 AEO62520.1 - 8.7 6.0 11.0 1.1 8.8 1.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Ribosomal_L7Ae PF01248.21 AEO62521.1 - 3.1e-25 87.5 0.1 3.8e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 AEO62521.1 - 0.0011 18.8 0.2 0.0059 16.4 0.2 1.9 1 1 0 1 1 1 1 RNase P subunit Pop3 Syja_N PF02383.13 AEO62522.1 - 4.1e-86 288.6 0.0 4.9e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Fn_bind PF02986.9 AEO62522.1 - 0.085 12.3 0.1 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Fibronectin binding repeat DUF3115 PF11312.3 AEO62523.1 - 2.6e-90 302.4 0.0 3.8e-90 301.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Transketolase_N PF00456.16 AEO62524.1 - 1.1e-153 510.9 0.1 1.4e-153 510.5 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 AEO62524.1 - 2.7e-45 154.0 0.0 4.4e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 AEO62524.1 - 4.5e-13 49.2 0.0 1.2e-12 47.8 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 AEO62524.1 - 3.9e-05 22.7 0.0 0.0015 17.4 0.0 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 AEO62524.1 - 0.0033 16.1 0.0 0.0053 15.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Filament PF00038.16 AEO62525.1 - 9e-05 22.0 11.2 9e-05 22.0 7.8 5.2 3 1 2 6 6 6 2 Intermediate filament protein V_ATPase_I PF01496.14 AEO62525.1 - 0.064 11.1 10.7 0.15 9.8 7.4 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 AEO62525.1 - 0.083 12.0 7.1 0.19 10.8 3.9 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 AEO62525.1 - 0.75 9.5 7.4 3.8 7.3 0.9 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TSC22 PF01166.13 AEO62525.1 - 1.1 9.2 20.9 12 5.9 3.1 5.4 5 0 0 5 5 5 0 TSC-22/dip/bun family Baculo_PEP_C PF04513.7 AEO62525.1 - 4 7.2 10.1 72 3.2 0.7 3.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HALZ PF02183.13 AEO62525.1 - 4.2 7.1 31.4 0.41 10.4 0.1 7.6 6 1 1 7 7 7 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 AEO62525.1 - 4.5 7.2 32.0 0.78 9.6 0.4 7.0 8 1 0 9 9 9 0 Flagella accessory protein C (FlaC) Abhydrolase_5 PF12695.2 AEO62526.1 - 3.6e-09 36.5 0.3 9.3e-09 35.1 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 AEO62526.1 - 1.9e-08 34.0 0.0 0.001 18.5 0.0 3.0 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 AEO62526.1 - 4.5e-08 33.2 8.5 0.0022 17.8 5.2 2.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 AEO62526.1 - 8.9e-05 22.0 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) LCCL PF03815.14 AEO62527.1 - 5.4e-20 71.1 0.1 9.7e-20 70.3 0.1 1.4 1 0 0 1 1 1 1 LCCL domain TGT PF01702.13 AEO62528.1 - 1.4e-33 116.1 0.0 2e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase GRA6 PF05084.8 AEO62528.1 - 0.014 14.9 2.0 0.014 14.9 1.4 1.7 2 0 0 2 2 2 0 Granule antigen protein (GRA6) Adaptin_N PF01602.15 AEO62529.1 - 3.6e-82 276.3 0.0 5.8e-82 275.6 0.0 1.3 1 1 0 1 1 1 1 Adaptin N terminal region TPR_19 PF14559.1 AEO62530.1 - 3.8e-09 36.7 0.3 0.00043 20.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 AEO62530.1 - 4.4e-09 35.8 2.5 0.00015 21.3 0.0 3.8 3 1 1 5 5 5 2 TPR repeat TPR_2 PF07719.12 AEO62530.1 - 4.9e-08 32.2 1.4 0.00016 21.2 0.0 4.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 AEO62530.1 - 7.4e-08 32.3 4.5 0.1 13.2 0.1 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 AEO62530.1 - 4.1e-06 27.3 10.5 5.8e-05 23.6 0.2 4.2 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 AEO62530.1 - 9.3e-05 22.2 0.8 0.15 12.0 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 AEO62530.1 - 0.0021 17.7 0.0 0.026 14.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 AEO62530.1 - 0.022 14.3 0.9 0.72 9.5 0.0 3.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 AEO62530.1 - 0.048 13.8 0.0 0.37 11.1 0.0 2.6 1 0 0 1 1 1 0 Tetratricopeptide repeat ChAPs PF09295.5 AEO62530.1 - 0.077 11.7 0.1 0.099 11.3 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) PPR_3 PF13812.1 AEO62530.1 - 0.098 12.9 0.0 0.43 10.9 0.0 2.1 1 0 0 1 1 1 0 Pentatricopeptide repeat domain TPR_9 PF13371.1 AEO62530.1 - 0.11 12.3 2.0 0.96 9.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SRP54_N PF02881.14 AEO62530.1 - 0.14 12.3 0.2 0.36 10.9 0.2 1.7 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain RuvA_C PF07499.8 AEO62530.1 - 0.65 10.2 4.6 18 5.5 0.1 3.3 3 0 0 3 3 2 0 RuvA, C-terminal domain TPR_6 PF13174.1 AEO62530.1 - 0.66 10.5 3.7 23 5.7 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF972 PF06156.8 AEO62531.1 - 0.32 11.3 9.1 0.098 13.0 2.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF1510 PF07423.6 AEO62531.1 - 0.98 8.7 13.9 1.2 8.5 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SAPS PF04499.10 AEO62531.1 - 1.1 7.7 4.4 1.2 7.6 3.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tox-REase-3 PF15647.1 AEO62531.1 - 2.1 8.1 10.7 3.1 7.6 7.4 1.2 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 DUF4557 PF15101.1 AEO62531.1 - 3.5 7.4 5.5 4 7.2 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Polyketide_cyc PF03364.15 AEO62533.1 - 2e-28 98.9 3.1 1.1e-27 96.5 2.1 2.0 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 AEO62533.1 - 4.7e-05 23.5 3.7 0.0073 16.4 0.3 2.4 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport MSP1_C PF07462.6 AEO62533.1 - 0.51 8.6 1.5 0.7 8.2 1.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF605 PF04652.11 AEO62533.1 - 3.7 6.8 11.7 5.9 6.1 8.1 1.3 1 0 0 1 1 1 0 Vta1 like DNA_pol_lambd_f PF10391.4 AEO62534.1 - 2.6e-22 78.0 0.9 5e-22 77.1 0.6 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 AEO62534.1 - 3.8e-20 71.3 0.0 8.3e-20 70.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 AEO62534.1 - 1.4e-19 70.1 0.0 2.7e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 AEO62534.1 - 5.9e-12 45.5 0.1 1.2e-11 44.5 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 AEO62534.1 - 0.0073 16.6 0.0 0.025 14.8 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_5 PF14520.1 AEO62534.1 - 0.016 15.3 0.0 0.2 11.8 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_2 PF12826.2 AEO62534.1 - 0.071 13.0 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif MAPEG PF01124.13 AEO62535.1 - 1.3e-24 86.2 2.9 1.5e-24 86.0 2.0 1.0 1 0 0 1 1 1 1 MAPEG family Sec23_trunk PF04811.10 AEO62536.1 - 2.4e-80 269.4 0.0 3.4e-80 268.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 AEO62536.1 - 2e-34 117.1 1.4 3.8e-34 116.2 0.1 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 AEO62536.1 - 5.2e-31 107.0 0.1 1.1e-30 105.9 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 AEO62536.1 - 3.1e-16 58.6 6.5 6.4e-16 57.6 4.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 AEO62536.1 - 5.9e-14 51.5 0.0 1.4e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L11_N PF03946.9 AEO62537.1 - 4.3e-18 64.5 0.1 6.6e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 AEO62537.1 - 2.7e-10 40.2 0.1 4.5e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Glyco_transf_41 PF13844.1 AEO62538.1 - 4.5e-97 324.9 0.0 1.4e-46 158.4 0.0 4.1 3 1 1 4 4 4 3 Glycosyl transferase family 41 TPR_1 PF00515.23 AEO62538.1 - 6.7e-27 91.9 1.6 2e-05 23.9 0.0 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 AEO62538.1 - 8.9e-26 89.3 4.1 6.9e-09 35.2 0.0 4.8 4 0 0 4 4 4 4 TPR repeat TPR_2 PF07719.12 AEO62538.1 - 1e-22 78.1 3.2 0.0021 17.8 0.0 7.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 AEO62538.1 - 7.5e-17 61.0 5.7 7.1e-07 29.0 0.1 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO62538.1 - 2.2e-15 55.1 0.1 0.014 15.0 0.0 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 AEO62538.1 - 2e-13 50.6 2.0 0.027 15.1 0.0 5.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 AEO62538.1 - 2.4e-12 45.9 0.2 0.0084 16.2 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 AEO62538.1 - 3.7e-11 42.6 8.2 0.0011 19.3 0.1 7.4 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.1 AEO62538.1 - 5.8e-10 38.7 11.1 0.11 12.4 0.2 6.6 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 AEO62538.1 - 1.2e-09 37.2 9.4 0.04 13.7 0.0 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 AEO62538.1 - 7.8e-07 29.3 1.2 0.28 11.5 0.0 4.2 3 1 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 AEO62538.1 - 1e-05 25.5 0.5 0.0082 16.2 0.0 3.7 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 AEO62538.1 - 0.00082 19.6 3.2 5.2 7.7 0.4 5.1 4 1 0 4 4 3 1 Tetratricopeptide repeat BTAD PF03704.12 AEO62538.1 - 0.0025 18.1 5.3 1.2 9.4 0.2 3.4 3 0 0 3 3 3 2 Bacterial transcriptional activator domain TPR_5 PF12688.2 AEO62538.1 - 0.031 14.3 1.4 0.67 9.9 0.0 3.2 4 0 0 4 4 3 0 Tetratrico peptide repeat TPR_9 PF13371.1 AEO62538.1 - 0.38 10.6 7.1 6.1 6.7 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.26 AEO62539.1 - 4.8e-22 77.7 2.5 7.4e-11 41.9 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO62539.1 - 1.3e-18 66.8 2.8 1e-12 47.9 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_Tnp_1 PF01527.15 AEO62539.1 - 0.056 13.3 0.7 0.19 11.6 0.5 1.9 1 0 0 1 1 1 0 Transposase Sigma70_r4_2 PF08281.7 AEO62539.1 - 0.075 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Myb_DNA-bind_4 PF13837.1 AEO62539.1 - 0.21 11.7 3.5 11 6.1 1.7 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 AEO62539.1 - 2.2 8.5 7.6 8.1 6.7 3.2 2.3 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like rRNA_proc-arch PF13234.1 AEO62540.1 - 0.14 11.3 0.6 0.21 10.7 0.4 1.2 1 0 0 1 1 1 0 rRNA-processing arch domain DUF2414 PF10309.4 AEO62541.1 - 2.9e-23 81.2 0.0 4.9e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) Pkinase PF00069.20 AEO62542.1 - 1e-66 224.7 0.0 1.2e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO62542.1 - 1e-37 129.6 0.0 1.3e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO62542.1 - 3.4e-08 32.8 0.0 6.8e-07 28.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AEO62542.1 - 0.00018 20.6 0.0 0.00028 19.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 AEO62542.1 - 0.08 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 AEO62542.1 - 0.13 11.6 0.1 0.45 9.8 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.18 AEO62542.1 - 0.24 11.1 10.0 0.27 10.9 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family zf-C4H2 PF10146.4 AEO62543.1 - 0.00012 22.1 0.1 0.0002 21.4 0.1 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein IncA PF04156.9 AEO62543.1 - 0.0021 17.6 13.9 0.0031 17.1 9.6 1.2 1 0 0 1 1 1 1 IncA protein FH2 PF02181.18 AEO62543.1 - 0.026 13.3 3.3 0.04 12.8 2.3 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain Tropomyosin PF00261.15 AEO62543.1 - 0.079 12.0 16.2 1.2 8.2 5.8 2.1 1 1 1 2 2 2 0 Tropomyosin KcnmB2_inactiv PF09303.5 AEO62543.1 - 0.16 11.7 4.0 0.44 10.3 2.8 1.7 1 0 0 1 1 1 0 KCNMB2, ball and chain domain Fmp27_WPPW PF10359.4 AEO62543.1 - 0.17 10.2 7.7 0.36 9.1 5.4 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Nup54 PF13874.1 AEO62543.1 - 0.52 9.9 7.2 0.86 9.2 1.0 2.5 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Exonuc_VII_L PF02601.10 AEO62543.1 - 0.54 9.4 4.0 0.8 8.8 2.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit IFT57 PF10498.4 AEO62543.1 - 0.65 8.6 9.0 1 7.9 6.2 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Tropomyosin_1 PF12718.2 AEO62543.1 - 1.2 9.0 20.7 3.6 7.4 2.8 2.2 1 1 1 2 2 2 0 Tropomyosin like EMP24_GP25L PF01105.19 AEO62543.1 - 1.4 8.5 6.6 10 5.7 0.1 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Syntaxin PF00804.20 AEO62543.1 - 1.5 9.0 8.3 0.28 11.3 1.4 2.2 1 1 1 2 2 2 0 Syntaxin Fib_alpha PF08702.5 AEO62543.1 - 2.2 8.4 5.5 2.1 8.4 2.8 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Tox-ODYAM1 PF15642.1 AEO62543.1 - 3.8 6.0 6.1 5.8 5.4 4.3 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus YlqD PF11068.3 AEO62543.1 - 5.1 7.1 10.5 1.5 8.9 0.3 2.2 1 1 1 2 2 2 0 YlqD protein DUF16 PF01519.11 AEO62543.1 - 7.9 6.7 8.3 18 5.6 4.5 2.4 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF4140 PF13600.1 AEO62543.1 - 9.9 6.6 10.9 4.3 7.8 1.1 3.3 3 1 1 4 4 3 0 N-terminal domain of unknown function (DUF4140) Pet127 PF08634.5 AEO62545.1 - 5.2e-121 402.9 0.5 5.2e-121 402.9 0.3 1.5 2 0 0 2 2 2 1 Mitochondrial protein Pet127 Rhomboid PF01694.17 AEO62546.1 - 2.1e-35 121.8 10.7 2.1e-35 121.8 7.4 2.5 3 0 0 3 3 3 1 Rhomboid family DUF1426 PF07234.6 AEO62546.1 - 1.4 8.6 4.4 21 4.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1426) Peptidase_M16_C PF05193.16 AEO62547.1 - 0.066 12.8 0.1 0.098 12.3 0.1 1.3 1 0 0 1 1 1 0 Peptidase M16 inactive domain Pex14_N PF04695.8 AEO62547.1 - 1.7 8.6 4.8 0.59 10.1 0.5 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Snf7 PF03357.16 AEO62548.1 - 6e-20 71.3 3.5 6e-20 71.3 2.4 1.9 2 0 0 2 2 2 1 Snf7 RseA_C PF03873.8 AEO62548.1 - 0.003 17.3 0.5 0.67 9.8 0.1 2.6 2 0 0 2 2 2 2 Anti sigma-E protein RseA, C-terminal domain Cohesin_load PF10345.4 AEO62549.1 - 4.5e-172 573.4 0.8 5.2e-172 573.2 0.6 1.0 1 0 0 1 1 1 1 Cohesin loading factor Abhydrolase_1 PF00561.15 AEO62550.1 - 2.5e-12 46.8 0.0 4.6e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AEO62550.1 - 2.7e-11 43.8 0.0 4.8e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO62550.1 - 2.7e-06 27.1 0.1 1.3e-05 24.9 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 AEO62550.1 - 0.0024 17.6 0.0 0.0088 15.7 0.0 2.0 2 0 0 2 2 2 1 Cutinase Peptidase_S15 PF02129.13 AEO62550.1 - 0.0057 16.1 0.0 0.0084 15.5 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF915 PF06028.6 AEO62550.1 - 0.025 13.6 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) T2SE_Nter PF05157.10 AEO62550.1 - 0.079 13.0 0.1 15 5.6 0.0 2.6 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein E, N-terminal domain IGPD PF00475.13 AEO62552.1 - 2.6e-60 202.4 0.4 5.1e-60 201.5 0.4 1.4 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase Rep_fac_C PF08542.6 AEO62554.1 - 8.7e-20 70.5 0.0 1.7e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 AEO62554.1 - 1.3e-12 47.7 0.0 9.2e-11 41.6 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 AEO62554.1 - 4.2e-12 46.4 0.1 8.2e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 AEO62554.1 - 1.9e-07 31.0 0.0 3.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO62554.1 - 1.9e-06 27.9 0.1 4.4e-05 23.5 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 AEO62554.1 - 1.3e-05 24.1 0.0 0.014 14.0 0.0 2.5 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 AEO62554.1 - 1.5e-05 25.1 0.1 0.0025 17.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AEO62554.1 - 2.2e-05 23.6 0.0 6e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 AEO62554.1 - 0.00011 21.8 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 AEO62554.1 - 0.00012 21.6 0.0 0.00025 20.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 AEO62554.1 - 0.0003 20.3 0.1 0.054 12.9 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain DNA_pol3_delta PF06144.8 AEO62554.1 - 0.001 18.5 0.1 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 AEO62554.1 - 0.0014 17.8 0.0 0.019 14.1 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 AEO62554.1 - 0.002 17.8 0.0 0.0047 16.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 AEO62554.1 - 0.0021 17.5 0.1 0.1 11.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain DNA_pol3_gamma3 PF12169.3 AEO62554.1 - 0.0028 17.4 0.2 0.37 10.5 0.0 2.7 3 0 0 3 3 2 1 DNA polymerase III subunits gamma and tau domain III AAA_5 PF07728.9 AEO62554.1 - 0.004 16.8 0.1 0.016 14.9 0.0 2.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 AEO62554.1 - 0.0084 15.8 0.5 0.051 13.2 0.1 2.3 2 1 1 3 3 2 1 NTPase KTI12 PF08433.5 AEO62554.1 - 0.014 14.6 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DEAD PF00270.24 AEO62554.1 - 0.014 14.8 0.1 0.25 10.7 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase ArgK PF03308.11 AEO62554.1 - 0.021 13.6 0.0 0.04 12.7 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_31 PF13614.1 AEO62554.1 - 0.025 14.5 0.0 0.055 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 AEO62554.1 - 0.025 14.1 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 AEO62554.1 - 0.029 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 AEO62554.1 - 0.059 13.6 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ArgJ PF01960.13 AEO62555.1 - 4.4e-149 496.1 0.4 5e-149 495.9 0.2 1.0 1 0 0 1 1 1 1 ArgJ family DER1 PF04511.10 AEO62556.1 - 2.5e-26 92.4 0.2 2.9e-26 92.2 0.1 1.0 1 0 0 1 1 1 1 Der1-like family DUF2269 PF10027.4 AEO62556.1 - 0.071 12.8 0.8 0.2 11.4 0.6 1.8 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2269) CD99L2 PF12301.3 AEO62557.1 - 0.0015 18.2 0.0 0.0015 18.2 0.0 3.9 4 1 0 4 4 4 1 CD99 antigen like protein 2 Ribosomal_60s PF00428.14 AEO62557.1 - 3.9 7.9 6.1 2.4 8.6 0.8 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein CN_hydrolase PF00795.17 AEO62560.1 - 2.8e-15 56.1 0.0 5e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CN_hydrolase PF00795.17 AEO62563.1 - 9.7e-11 41.3 0.0 1.7e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TSA PF03249.8 AEO62564.1 - 0.038 12.5 0.4 0.04 12.4 0.3 1.0 1 0 0 1 1 1 0 Type specific antigen PDGF_N PF04692.8 AEO62564.1 - 0.38 11.2 3.1 0.47 10.9 2.2 1.1 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region BAF1_ABF1 PF04684.8 AEO62564.1 - 2.7 6.7 14.4 2.6 6.7 10.0 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DKCLD PF08068.7 AEO62566.1 - 1.2e-29 102.0 0.2 5.4e-29 99.8 0.1 2.1 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 AEO62566.1 - 2.1e-24 86.4 0.1 2e-21 76.7 0.1 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 AEO62566.1 - 2.3e-21 75.3 0.9 5.1e-21 74.1 0.6 1.6 1 0 0 1 1 1 1 PUA domain SOBP PF15279.1 AEO62566.1 - 3.4 7.9 7.2 5.3 7.3 5.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein EphA2_TM PF14575.1 AEO62567.1 - 0.0095 16.3 0.1 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4229 PF14012.1 AEO62567.1 - 0.039 13.8 0.5 0.078 12.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DAP10 PF07213.6 AEO62567.1 - 0.74 9.6 3.4 0.32 10.7 0.2 2.1 2 0 0 2 2 2 0 DAP10 membrane protein DUF2613 PF11021.3 AEO62567.1 - 2.1 8.1 5.3 1.2 8.9 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) SAC3_GANP PF03399.11 AEO62569.1 - 1.5e-43 148.7 0.3 2e-43 148.3 0.2 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 AEO62569.1 - 0.0011 18.7 0.0 0.0028 17.4 0.0 1.7 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 Methyltransf_12 PF08242.7 AEO62570.1 - 1.5e-14 54.2 0.0 3.8e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO62570.1 - 1.4e-10 41.5 0.0 3e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO62570.1 - 1.8e-10 40.7 0.0 3.3e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO62570.1 - 8.3e-10 38.9 0.0 1.6e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO62570.1 - 4.4e-08 33.6 0.0 1.3e-07 32.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO62570.1 - 5.7e-08 32.4 0.0 1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO62570.1 - 3e-07 29.8 0.0 4.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AEO62570.1 - 5.7e-05 23.1 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO62570.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 AEO62570.1 - 0.003 17.2 0.0 0.016 14.8 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase DUF3419 PF11899.3 AEO62570.1 - 0.011 14.5 0.0 0.015 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Methyltransf_24 PF13578.1 AEO62570.1 - 0.049 14.4 0.0 0.23 12.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.4 AEO62570.1 - 0.088 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Bromodomain PF00439.20 AEO62571.1 - 6.3e-25 86.9 0.2 1.5e-24 85.6 0.2 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 AEO62571.1 - 7.8e-10 38.7 0.2 2e-09 37.4 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO62571.1 - 3.6e-09 36.5 0.1 9.5e-09 35.1 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 AEO62571.1 - 0.08 13.1 0.0 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain NAD_synthase PF02540.12 AEO62572.1 - 0.01 14.7 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 0 NAD synthase CN_hydrolase PF00795.17 AEO62573.1 - 4.8e-26 91.2 0.0 7.1e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 AEO62573.1 - 9.8e-09 34.4 0.0 3.2e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 NAD synthase TFIIE_alpha PF02002.12 AEO62574.1 - 6e-17 61.0 0.1 1.1e-16 60.2 0.1 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit zf-FPG_IleRS PF06827.9 AEO62574.1 - 0.022 14.4 1.6 0.57 9.8 0.0 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF2387 PF09526.5 AEO62574.1 - 0.025 14.4 0.3 0.09 12.7 0.2 2.0 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) zinc-ribbons_6 PF07191.7 AEO62574.1 - 0.029 14.1 0.2 0.063 13.0 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbons Zn-ribbon_8 PF09723.5 AEO62574.1 - 0.079 12.9 1.2 0.32 10.9 0.7 2.1 1 1 1 2 2 2 0 Zinc ribbon domain DZR PF12773.2 AEO62574.1 - 0.16 11.8 0.9 0.43 10.4 0.7 1.7 1 1 0 1 1 1 0 Double zinc ribbon RRN7 PF11781.3 AEO62574.1 - 0.28 10.7 3.4 5.8 6.4 0.3 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF2838 PF10998.3 AEO62575.1 - 3e-46 155.8 10.8 3e-46 155.8 7.5 2.6 3 1 0 3 3 3 1 Protein of unknown function (DUF2838) Tropomyosin_1 PF12718.2 AEO62575.1 - 0.047 13.5 0.3 0.092 12.5 0.2 1.4 1 0 0 1 1 1 0 Tropomyosin like Atg14 PF10186.4 AEO62575.1 - 0.28 10.0 0.8 0.4 9.5 0.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 AEO62575.1 - 0.35 10.4 1.4 0.65 9.5 1.0 1.3 1 0 0 1 1 1 0 IncA protein WD40 PF00400.27 AEO62576.1 - 2.8e-35 118.9 5.0 3e-07 30.0 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 AEO62576.1 - 3.4e-07 30.1 0.1 0.024 14.3 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 AEO62576.1 - 0.12 11.1 0.1 0.41 9.3 0.0 1.7 2 0 0 2 2 2 0 Coatomer WD associated region Pribosyltran_N PF13793.1 AEO62577.1 - 1.1e-25 89.5 0.0 4.6e-25 87.6 0.0 2.0 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 AEO62577.1 - 0.0016 18.2 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Orn_Arg_deC_N PF02784.11 AEO62578.1 - 6.9e-78 261.2 0.0 9.3e-78 260.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 AEO62578.1 - 5.9e-31 106.5 0.1 1.3e-30 105.4 0.1 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain M16C_assoc PF08367.6 AEO62579.1 - 1.1e-59 201.2 0.0 1.6e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 AEO62579.1 - 1.4e-35 122.6 0.0 1.2e-20 73.9 0.0 3.2 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AEO62579.1 - 1.1e-07 31.7 0.0 4.2e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) HHH_8 PF14716.1 AEO62579.1 - 0.011 15.9 0.0 0.35 11.0 0.0 3.2 3 0 0 3 3 3 0 Helix-hairpin-helix domain Taxilin PF09728.4 AEO62580.1 - 1.1e-88 297.3 55.5 1.4e-88 296.9 38.5 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF904 PF06005.7 AEO62580.1 - 0.0017 18.6 9.2 0.0017 18.6 6.4 5.1 3 2 1 4 4 4 1 Protein of unknown function (DUF904) bZIP_2 PF07716.10 AEO62580.1 - 0.016 15.0 2.6 0.016 15.0 1.8 5.2 5 1 1 6 6 6 0 Basic region leucine zipper NPV_P10 PF05531.7 AEO62580.1 - 0.2 11.9 14.6 1.6 8.9 1.8 3.8 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein FliD_N PF02465.13 AEO62580.1 - 0.94 9.8 19.0 2.2 8.7 0.5 4.2 2 1 2 4 4 4 0 Flagellar hook-associated protein 2 N-terminus TMF_TATA_bd PF12325.3 AEO62580.1 - 1.3 8.7 52.3 0.61 9.8 11.3 4.7 3 2 1 4 4 4 0 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.4 AEO62580.1 - 7.7 6.7 27.6 0.21 11.7 5.1 3.9 2 2 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 eIF-3_zeta PF05091.7 AEO62581.1 - 1.1 7.8 4.7 2 6.9 3.3 1.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NMO PF03060.10 AEO62582.1 - 4.9e-69 232.9 3.7 5.8e-69 232.7 2.6 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 AEO62582.1 - 1.9e-06 27.0 0.0 0.036 12.9 0.0 2.6 2 1 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 AEO62582.1 - 0.0023 16.8 4.7 0.0023 16.8 3.2 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Acetyltransf_1 PF00583.19 AEO62583.1 - 1.1e-17 63.7 0.0 1.5e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO62583.1 - 2.4e-07 30.8 0.1 5.1e-07 29.7 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO62583.1 - 1.6e-06 27.7 0.0 2.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 AEO62583.1 - 9.9e-06 25.5 0.1 1.4e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO62583.1 - 1.1e-05 25.5 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AEO62583.1 - 2.6e-05 24.1 0.7 3.5e-05 23.7 0.0 1.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO62583.1 - 7.2e-05 22.6 0.0 9.4e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_M16_C PF05193.16 AEO62585.1 - 2e-22 79.7 0.0 1.6e-15 57.2 0.0 3.4 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AEO62585.1 - 4.3e-06 26.5 0.0 1.7e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) RQC PF09382.5 AEO62585.1 - 0.11 12.2 0.1 0.55 9.9 0.0 2.2 2 0 0 2 2 2 0 RQC domain Ribosomal_L36e PF01158.13 AEO62586.1 - 2.9e-40 136.1 5.8 3.4e-40 135.9 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 AEO62586.1 - 0.018 14.1 0.1 0.02 14.0 0.1 1.1 1 0 0 1 1 1 0 LemA family MRP-L28 PF09812.4 AEO62586.1 - 0.051 13.4 1.0 0.059 13.1 0.7 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Zw10 PF06248.8 AEO62587.1 - 3.6e-11 41.9 0.8 7.2e-11 40.9 0.5 1.4 1 1 0 1 1 1 1 Centromere/kinetochore Zw10 Daxx PF03344.10 AEO62587.1 - 0.012 14.0 1.2 0.022 13.2 0.8 1.4 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 AEO62587.1 - 0.025 13.6 5.7 0.056 12.5 4.0 1.6 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 AEO62587.1 - 0.028 12.3 7.5 0.047 11.6 5.2 1.3 1 0 0 1 1 1 0 Nop14-like family MutS_III PF05192.13 AEO62587.1 - 0.58 9.9 4.0 0.26 11.0 0.7 2.0 2 1 0 2 2 2 0 MutS domain III DUF2631 PF10939.3 AEO62587.1 - 2.3 8.1 7.7 0.18 11.6 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2631) PI-PLC-X PF00388.14 AEO62588.1 - 1.4e-54 183.4 0.0 2.7e-54 182.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 AEO62588.1 - 1.3e-38 131.5 0.0 2.9e-38 130.4 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 AEO62588.1 - 4.1e-10 39.3 0.1 1e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.6 AEO62588.1 - 7.9e-06 25.8 0.1 2.9e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like Mcp5_PH PF12814.2 AEO62588.1 - 0.0014 18.5 0.5 0.0028 17.5 0.3 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology GDPD PF03009.12 AEO62588.1 - 0.0015 18.1 0.1 0.0082 15.6 0.0 2.2 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family PH PF00169.24 AEO62588.1 - 0.0053 16.9 0.2 0.013 15.6 0.2 1.7 1 0 0 1 1 1 1 PH domain zf-DHHC PF01529.15 AEO62589.1 - 2.2e-40 137.8 8.8 2.2e-40 137.8 6.1 3.5 3 1 0 3 3 2 1 DHHC palmitoyltransferase PAT1 PF09770.4 AEO62589.1 - 0.00024 19.5 48.1 0.00024 19.5 33.4 1.7 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 Zip PF02535.17 AEO62589.1 - 0.00032 19.8 14.3 0.00069 18.7 9.9 1.7 1 0 0 1 1 1 1 ZIP Zinc transporter Med15 PF09606.5 AEO62589.1 - 0.0017 16.6 67.0 0.0032 15.7 46.4 1.4 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal HlyD_2 PF12700.2 AEO62589.1 - 0.017 14.2 8.5 0.024 13.8 5.9 1.1 1 0 0 1 1 1 0 HlyD family secretion protein TFIIA PF03153.8 AEO62589.1 - 0.029 14.2 34.7 0.044 13.6 24.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MMR1 PF08505.5 AEO62589.1 - 0.055 13.4 21.7 0.088 12.8 15.0 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Macoilin PF09726.4 AEO62589.1 - 0.67 8.1 23.8 1.2 7.3 16.5 1.4 1 0 0 1 1 1 0 Transmembrane protein Ycf1 PF05758.7 AEO62589.1 - 1.8 6.1 25.0 2.5 5.6 17.3 1.1 1 0 0 1 1 1 0 Ycf1 FAM60A PF15396.1 AEO62589.1 - 2.4 7.8 19.1 4.6 6.9 13.2 1.4 1 0 0 1 1 1 0 Protein Family FAM60A AvrE PF11725.3 AEO62589.1 - 2.6 4.9 24.9 3.4 4.5 17.3 1.0 1 0 0 1 1 1 0 Pathogenicity factor zf-C2H2_4 PF13894.1 AEO62590.1 - 1.3e-06 28.3 9.8 0.048 14.0 0.1 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO62590.1 - 6e-06 26.3 16.2 0.0012 19.0 0.2 4.4 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 AEO62590.1 - 0.0001 22.3 10.6 0.01 15.9 0.8 3.3 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 AEO62590.1 - 0.017 15.3 18.9 0.06 13.6 0.1 5.0 6 0 0 6 6 6 0 Zinc-finger double domain zf-met PF12874.2 AEO62590.1 - 0.019 15.1 2.2 5.5 7.3 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 AEO62590.1 - 0.031 13.9 9.1 1.7 8.4 0.2 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Trm112p PF03966.11 AEO62590.1 - 0.071 13.4 0.6 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Trm112p-like protein zf-C2H2_2 PF12756.2 AEO62590.1 - 0.23 11.6 9.3 6.4 6.9 0.1 3.8 2 2 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.1 AEO62590.1 - 1.3 8.7 11.2 3.1 7.5 0.4 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AEO62590.1 - 1.5 8.4 11.3 2.8 7.6 0.4 4.0 4 0 0 4 4 4 0 zinc-ribbon domain AIG2 PF06094.7 AEO62591.1 - 6.6e-09 36.1 0.0 1e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family UQ_con PF00179.21 AEO62592.1 - 1.3e-19 69.9 0.0 2.8e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AEO62592.1 - 0.043 13.7 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain B-block_TFIIIC PF04182.7 AEO62593.1 - 4e-17 61.8 0.0 2.1e-16 59.5 0.0 2.1 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC RNA_pol_Rpc34 PF05158.7 AEO62593.1 - 0.39 9.8 0.0 0.95 8.5 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit CHD5 PF04420.9 AEO62594.1 - 0.12 11.9 1.7 0.21 11.2 1.2 1.3 1 0 0 1 1 1 0 CHD5-like protein Ebp2 PF05890.7 AEO62597.1 - 3.6e-88 295.4 21.7 3.6e-88 295.4 15.0 2.2 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DUF1768 PF08719.6 AEO62597.1 - 0.0044 16.7 2.2 0.011 15.4 1.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) zf-MYND PF01753.13 AEO62598.1 - 6.6e-08 32.2 19.6 1.9e-07 30.8 13.6 1.8 1 0 0 1 1 1 1 MYND finger Zn_clus PF00172.13 AEO62600.1 - 7.1e-10 38.6 7.6 1.4e-09 37.6 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.5 AEO62600.1 - 0.62 10.2 4.0 0.33 11.0 0.8 2.0 2 0 0 2 2 2 0 Opy2 protein MFS_1 PF07690.11 AEO62601.1 - 4.6e-30 104.5 61.2 4.6e-30 104.5 42.4 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO62601.1 - 7.8e-08 31.3 56.4 5.5e-07 28.5 10.6 4.2 2 1 2 4 4 4 2 Sugar (and other) transporter OATP PF03137.15 AEO62601.1 - 0.00029 19.0 1.2 0.00029 19.0 0.8 2.4 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Cu-oxidase_2 PF07731.9 AEO62602.1 - 1.7e-35 121.5 5.4 5.8e-34 116.5 2.0 2.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 AEO62602.1 - 1.4e-31 109.5 0.0 4e-29 101.5 0.0 2.2 2 0 0 2 2 2 2 Multicopper oxidase Cupin_2 PF07883.6 AEO62603.1 - 0.0054 16.2 0.0 0.27 10.7 0.0 2.4 1 1 0 1 1 1 1 Cupin domain APH PF01636.18 AEO62604.1 - 0.005 16.6 0.1 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO62604.1 - 0.093 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.20 AEO62605.1 - 9.7e-22 77.6 0.3 2.2e-21 76.4 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO62605.1 - 2e-08 34.1 0.1 4.7e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 AEO62605.1 - 0.00012 21.9 0.0 0.00021 21.1 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AEO62605.1 - 0.0056 16.1 0.0 0.012 15.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 AEO62605.1 - 0.012 15.3 0.3 0.026 14.2 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_transf_4 PF13439.1 AEO62605.1 - 0.096 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 NAD_binding_7 PF13241.1 AEO62605.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 AEO62605.1 - 0.13 12.2 1.3 0.5 10.3 0.9 2.0 1 1 0 1 1 1 0 NADH(P)-binding Cytochrom_B_N PF00033.14 AEO62606.1 - 6.2 6.1 14.0 2.1e+02 1.1 9.7 2.6 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Cation_efflux PF01545.16 AEO62607.1 - 7.9e-22 77.6 14.9 1.9e-19 69.8 8.5 2.1 2 0 0 2 2 2 2 Cation efflux family GATase_4 PF13230.1 AEO62608.1 - 2.7e-18 65.6 0.0 2.1e-16 59.4 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 AEO62608.1 - 9.9e-09 35.2 0.0 1.9e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 AEO62608.1 - 1.1e-06 27.6 0.0 7e-05 21.6 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Dynamin_N PF00350.18 AEO62609.1 - 9.9e-42 142.6 0.2 2.1e-41 141.5 0.0 1.7 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 AEO62609.1 - 1.2e-05 24.2 0.1 3.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 AEO62609.1 - 0.0016 18.3 0.0 0.0059 16.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AEO62609.1 - 0.0033 17.8 0.0 0.01 16.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein STAT_int PF02865.12 AEO62609.1 - 0.011 15.7 1.3 0.045 13.7 0.4 2.3 2 0 0 2 2 2 0 STAT protein, protein interaction domain AAA_16 PF13191.1 AEO62609.1 - 0.038 13.9 0.5 0.22 11.4 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.1 AEO62609.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Med5 PF08689.5 AEO62612.1 - 4.5e-261 868.7 0.0 5.9e-261 868.3 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 PAT1 PF09770.4 AEO62613.1 - 0.051 11.8 20.4 0.067 11.4 14.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pox_A12 PF04651.8 AEO62613.1 - 0.074 13.1 4.4 0.12 12.4 3.0 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein Macoilin PF09726.4 AEO62613.1 - 1.2 7.3 8.7 1.8 6.7 6.1 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF822 PF05687.8 AEO62613.1 - 6.1 7.1 9.8 14 6.0 6.8 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) DUF2273 PF10031.4 AEO62613.1 - 6.6 6.4 8.0 15 5.2 5.6 1.5 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) DUF1517 PF07466.6 AEO62613.1 - 7.1 5.5 16.9 0.03 13.3 5.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) FMN_dh PF01070.13 AEO62614.1 - 4.3e-88 295.5 0.0 7.4e-88 294.7 0.0 1.3 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 AEO62614.1 - 1.5e-19 69.5 0.0 2.4e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 AEO62614.1 - 0.0006 18.8 0.3 0.00092 18.2 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 AEO62614.1 - 0.012 14.6 0.3 4.2 6.3 0.1 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 AEO62614.1 - 0.11 11.3 1.1 0.35 9.6 0.1 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 AEO62614.1 - 0.2 10.5 0.1 17 4.2 0.0 2.2 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase NMO PF03060.10 AEO62614.1 - 0.2 10.7 3.0 0.37 9.9 2.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase DUF4202 PF13875.1 AEO62615.1 - 3.2e-77 258.3 0.7 3.6e-77 258.2 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) OmpH PF03938.9 AEO62618.1 - 0.0063 16.4 17.7 0.0063 16.4 12.3 1.5 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) SR-25 PF10500.4 AEO62618.1 - 0.01 15.3 7.8 0.01 15.3 5.4 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein MRP-S31 PF15433.1 AEO62618.1 - 0.84 8.9 11.2 3.1 7.1 5.2 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 DUF3801 PF12687.2 AEO62618.1 - 1.3 8.5 14.6 0.031 13.8 3.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) MSP1_C PF07462.6 AEO62618.1 - 4.3 5.6 10.4 5.7 5.1 7.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus 14-3-3 PF00244.15 AEO62619.1 - 1e-08 34.5 0.1 4.1e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 14-3-3 protein Sterol-sensing PF12349.3 AEO62622.1 - 7.2e-35 119.7 10.8 1.2e-34 118.9 7.5 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 AEO62622.1 - 1e-09 36.9 1.3 1.3e-09 36.5 0.9 1.2 1 0 0 1 1 1 1 Patched family WD40 PF00400.27 AEO62622.1 - 0.071 13.0 0.1 5 7.1 0.0 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat Cupin_8 PF13621.1 AEO62623.1 - 3.4e-64 216.7 0.0 4.5e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 AEO62623.1 - 3.7e-06 26.4 0.0 0.00069 18.9 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein Spb1_C PF07780.7 AEO62624.1 - 1.1e-78 263.6 28.9 1.1e-78 263.6 20.1 4.0 3 2 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.14 AEO62624.1 - 2.9e-55 187.0 0.0 2.6e-54 183.9 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.3 AEO62624.1 - 7e-55 184.8 11.4 7e-55 184.8 7.9 4.9 3 2 1 5 5 5 1 Domain of unknown function (DUF3381) YgaB PF14182.1 AEO62624.1 - 0.11 12.7 8.5 0.65 10.2 5.9 2.4 1 0 0 1 1 1 0 YgaB-like protein WD40 PF00400.27 AEO62625.1 - 2.6e-24 84.1 4.8 3.4e-07 29.9 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat EamA PF00892.15 AEO62626.1 - 8.3e-08 32.3 29.4 1e-06 28.8 1.7 3.1 3 1 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 AEO62626.1 - 9.1e-06 24.7 7.9 9.1e-06 24.7 5.4 2.0 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 AEO62626.1 - 3.8e-05 22.7 8.3 3.8e-05 22.7 5.7 1.5 2 0 0 2 2 2 1 UAA transporter family DUF3955 PF13127.1 AEO62626.1 - 0.00056 19.4 0.8 0.00056 19.4 0.6 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF3955) EmrE PF13536.1 AEO62626.1 - 0.00082 19.5 5.6 0.00082 19.5 3.9 3.5 3 2 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 AEO62626.1 - 0.012 15.2 22.8 0.028 14.0 2.6 2.9 3 0 0 3 3 3 0 Triose-phosphate Transporter family Ras PF00071.17 AEO62627.1 - 2.8e-57 192.6 0.1 3.3e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO62627.1 - 3.2e-18 66.3 0.0 4.7e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO62627.1 - 7.8e-14 51.2 0.0 9.2e-14 51.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 AEO62627.1 - 4.6e-08 33.0 0.0 6.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 AEO62627.1 - 7.8e-08 31.7 0.0 9.5e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AEO62627.1 - 9.6e-07 28.4 0.0 1.9e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 AEO62627.1 - 0.00072 19.6 0.0 0.001 19.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AEO62627.1 - 0.00088 18.4 0.1 0.0017 17.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 AEO62627.1 - 0.0013 18.0 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 AEO62627.1 - 0.0032 17.1 0.0 0.011 15.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 AEO62627.1 - 0.0038 16.8 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 AEO62627.1 - 0.0052 16.3 0.3 0.2 11.1 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 AEO62627.1 - 0.0054 16.4 0.1 0.01 15.5 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 AEO62627.1 - 0.006 16.5 0.0 0.013 15.4 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.4 AEO62627.1 - 0.0064 15.9 0.1 0.095 12.1 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 AEO62627.1 - 0.0067 15.8 0.2 0.011 15.2 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain Septin PF00735.13 AEO62627.1 - 0.011 14.8 0.1 0.026 13.5 0.0 1.7 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.10 AEO62627.1 - 0.014 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 NTPase MobB PF03205.9 AEO62627.1 - 0.024 14.3 0.1 0.052 13.2 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 AEO62627.1 - 0.024 14.0 0.0 0.063 12.7 0.0 1.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 AEO62627.1 - 0.05 13.7 0.1 0.24 11.6 0.1 2.1 1 1 0 1 1 1 0 RNA helicase FeoB_N PF02421.13 AEO62627.1 - 0.079 12.2 0.0 0.97 8.7 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.7 AEO62627.1 - 0.084 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_3 PF07726.6 AEO62628.1 - 0.0017 18.0 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Pex14_N PF04695.8 AEO62628.1 - 0.041 13.9 1.0 0.13 12.3 0.7 1.9 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SOG2 PF10428.4 AEO62628.1 - 1.4 7.5 11.4 2.6 6.5 7.9 1.5 1 1 0 1 1 1 0 RAM signalling pathway protein GDA1_CD39 PF01150.12 AEO62629.1 - 4.3e-96 322.0 0.0 5.3e-96 321.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PUL PF08324.6 AEO62631.1 - 5.1e-38 130.4 0.0 6.5e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 AEO62631.1 - 1.9e-33 115.3 0.0 3.1e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 AEO62631.1 - 9.1e-13 47.8 0.0 1.6e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AEO62631.1 - 0.0031 17.6 0.0 0.013 15.6 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 AEO62631.1 - 0.044 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain AhpC-TSA PF00578.16 AEO62631.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Kinesin PF00225.18 AEO62632.1 - 6.4e-114 380.1 0.0 9.1e-114 379.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF972 PF06156.8 AEO62632.1 - 0.019 15.3 0.5 7.8 6.8 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF87 PF01935.12 AEO62632.1 - 0.15 11.8 3.5 0.67 9.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 DUF4315 PF14193.1 AEO62632.1 - 0.44 10.4 5.2 2.1 8.3 3.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4315) DUF4598 PF15370.1 AEO62633.1 - 0.012 15.8 3.0 0.012 15.8 2.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4598) IF4E PF01652.13 AEO62634.1 - 3.1e-36 124.3 0.0 4.1e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E EF-hand_9 PF14658.1 AEO62635.1 - 0.0092 15.8 0.0 0.66 9.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain Ribosomal_60s PF00428.14 AEO62635.1 - 0.013 15.8 0.8 0.031 14.6 0.6 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Lactamase_B PF00753.22 AEO62636.1 - 6.2e-30 104.2 3.1 8.1e-30 103.9 2.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AEO62636.1 - 1.5e-05 24.6 0.1 1.9e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF1236 PF06823.7 AEO62636.1 - 0.0018 17.9 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1236) LVIVD PF08309.6 AEO62636.1 - 0.099 11.6 0.2 0.18 10.7 0.1 1.4 1 0 0 1 1 1 0 LVIVD repeat Las1 PF04031.8 AEO62637.1 - 3.1e-24 85.4 0.3 5.7e-24 84.5 0.2 1.5 1 0 0 1 1 1 1 Las1-like TMCO5 PF14992.1 AEO62637.1 - 0.96 8.5 4.7 1.4 7.9 3.2 1.1 1 0 0 1 1 1 0 TMCO5 family Saccharop_dh PF03435.13 AEO62638.1 - 1.6e-132 442.1 0.0 1.8e-132 441.9 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 AEO62638.1 - 2.8e-05 24.2 0.1 6e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 AEO62638.1 - 4e-05 23.7 0.5 7.3e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 NADH(P)-binding IlvN PF07991.7 AEO62638.1 - 0.0029 16.9 0.6 0.057 12.7 0.1 2.8 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain GFO_IDH_MocA PF01408.17 AEO62638.1 - 0.036 14.5 0.1 0.075 13.5 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PfkB PF00294.19 AEO62640.1 - 0.0008 18.6 0.0 0.017 14.2 0.0 2.1 2 1 0 2 2 2 2 pfkB family carbohydrate kinase NAD_kinase PF01513.16 AEO62641.1 - 3.3e-70 236.1 0.0 4.7e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase GTP_EFTU PF00009.22 AEO62643.1 - 1.3e-59 200.7 0.0 1.7e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AEO62643.1 - 4.1e-24 84.6 0.1 8.6e-24 83.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AEO62643.1 - 5.6e-16 58.4 3.5 5.6e-16 58.4 2.4 2.3 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AEO62643.1 - 2.8e-05 24.0 0.0 5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 AEO62643.1 - 0.00011 21.7 0.7 0.00031 20.3 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 AEO62643.1 - 0.002 18.5 0.0 0.0034 17.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 AEO62643.1 - 0.069 12.6 0.2 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_S14 PF00253.16 AEO62644.1 - 1.1e-20 72.7 3.8 1.2e-20 72.6 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.7 AEO62644.1 - 0.02 14.9 0.9 2.2 8.4 0.1 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF4428 PF14471.1 AEO62644.1 - 0.1 12.3 0.5 0.13 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) A2L_zn_ribbon PF08792.5 AEO62644.1 - 0.16 11.4 0.9 0.26 10.7 0.6 1.3 1 0 0 1 1 1 0 A2L zinc ribbon domain Thioredoxin PF00085.15 AEO62645.1 - 8.7e-65 214.9 0.0 5e-31 106.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 AEO62645.1 - 5.3e-25 87.8 2.0 1e-24 86.9 0.5 2.2 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 AEO62645.1 - 2.2e-21 76.1 0.2 3e-09 37.0 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 AEO62645.1 - 3.3e-14 52.6 0.0 5.1e-06 26.4 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 AEO62645.1 - 5.2e-14 52.1 0.0 2.2e-05 24.5 0.0 3.0 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 AEO62645.1 - 9.7e-08 31.7 0.1 0.0047 16.5 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 AEO62645.1 - 1.9e-07 30.7 0.4 0.024 14.1 0.0 2.8 3 0 0 3 3 3 2 Redoxin ERp29_N PF07912.8 AEO62645.1 - 1.7e-06 27.9 0.0 0.0019 18.1 0.0 2.4 2 0 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_6 PF13848.1 AEO62645.1 - 2.3e-06 27.5 0.1 0.015 15.0 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_9 PF14595.1 AEO62645.1 - 8.4e-06 25.3 0.2 0.016 14.7 0.0 2.9 3 1 1 4 4 4 2 Thioredoxin Thioredoxin_3 PF13192.1 AEO62645.1 - 0.00012 21.8 0.0 0.52 10.1 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_4 PF13462.1 AEO62645.1 - 0.00016 21.6 1.4 0.89 9.5 0.0 3.6 3 2 1 4 4 4 2 Thioredoxin Glutaredoxin PF00462.19 AEO62645.1 - 0.0017 18.3 0.1 2.7 8.0 0.0 2.9 2 1 0 2 2 2 2 Glutaredoxin HyaE PF07449.6 AEO62645.1 - 0.0017 18.2 0.0 0.099 12.5 0.0 2.7 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE DDE_Tnp_1_2 PF13586.1 AEO62645.1 - 0.0088 16.2 0.0 4 7.6 0.0 2.6 2 0 0 2 2 2 1 Transposase DDE domain zf-rbx1 PF12678.2 AEO62646.1 - 5.7e-09 35.9 0.4 1e-08 35.1 0.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 AEO62646.1 - 7.3e-08 32.1 8.5 5e-07 29.4 5.9 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AEO62646.1 - 2.4e-07 30.3 0.6 3.8e-07 29.6 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO62646.1 - 1.8e-05 24.3 3.5 3.9e-05 23.2 2.5 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO62646.1 - 0.0001 22.2 2.6 0.0001 22.2 1.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO62646.1 - 0.00011 21.7 3.2 0.00031 20.3 2.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2921 PF11145.3 AEO62646.1 - 0.0045 14.7 0.2 0.0065 14.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2921) zf-Apc11 PF12861.2 AEO62646.1 - 0.0067 16.2 0.9 0.017 14.9 0.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger VIT1 PF01988.14 AEO62646.1 - 0.013 15.0 2.8 0.21 11.0 1.9 2.3 1 1 0 1 1 1 0 VIT family RINGv PF12906.2 AEO62646.1 - 0.34 10.9 1.6 0.85 9.7 1.1 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 AEO62646.1 - 2 8.1 8.2 0.067 12.9 0.6 2.4 2 1 1 3 3 3 0 RING-type zinc-finger FANCL_C PF11793.3 AEO62646.1 - 7.2 6.6 6.6 1.9 8.5 1.9 1.9 2 1 0 2 2 2 0 FANCL C-terminal domain Herpes_gE PF02480.11 AEO62646.1 - 8 4.6 6.0 0.42 8.8 0.4 1.5 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Rb_C PF08934.5 AEO62647.1 - 1.4 8.5 3.6 1.6 8.3 2.5 1.1 1 0 0 1 1 1 0 Rb C-terminal domain HAD_2 PF13419.1 AEO62648.1 - 6.3e-20 72.1 0.0 8.7e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AEO62648.1 - 2.1e-11 44.6 0.1 7.8e-11 42.7 0.0 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO62648.1 - 1.1e-09 37.8 0.0 2.2e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.13 AEO62648.1 - 0.00028 20.5 0.0 0.0097 15.5 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.2 AEO62648.1 - 0.0036 17.5 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 AEO62648.1 - 0.014 15.2 0.0 6.5 6.7 0.0 2.5 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Init_tRNA_PT PF04179.7 AEO62649.1 - 2.9e-148 494.4 0.0 3.4e-148 494.2 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Zn_clus PF00172.13 AEO62650.1 - 4.6e-06 26.4 5.9 1.1e-05 25.2 4.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO62650.1 - 6.9e-06 24.9 0.1 1e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DnaJ PF00226.26 AEO62651.1 - 2.6e-28 97.5 4.5 3.9e-28 96.9 3.1 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AEO62651.1 - 4e-22 77.8 1.7 2.1e-19 69.1 0.1 2.3 2 0 0 2 2 2 2 DnaJ C terminal domain Malate_DH PF12434.3 AEO62651.1 - 0.09 12.4 2.4 0.24 11.1 1.7 1.7 1 1 0 1 1 1 0 Malate dehydrogenase enzyme Ribosomal_L37ae PF01780.14 AEO62653.1 - 7.3e-35 118.7 4.1 8e-35 118.5 2.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 AEO62653.1 - 0.0019 17.9 3.7 0.0019 17.9 2.6 1.6 2 0 0 2 2 2 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 AEO62653.1 - 0.019 14.3 0.8 2.8 7.5 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain OrfB_Zn_ribbon PF07282.6 AEO62653.1 - 0.13 11.9 1.7 0.22 11.2 1.2 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain C1_1 PF00130.17 AEO62653.1 - 0.19 11.4 3.9 0.23 11.1 1.4 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CarbpepA_inh PF02977.10 AEO62653.1 - 0.45 10.1 2.8 0.49 10.0 0.3 2.1 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor zf-BED PF02892.10 AEO62653.1 - 1 9.1 5.3 2.6 7.8 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger DUF2823 PF11034.3 AEO62655.1 - 4.7e-34 116.3 11.0 5.2e-34 116.1 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) MT0933_antitox PF14013.1 AEO62655.1 - 0.017 15.2 6.2 0.12 12.4 3.8 2.1 1 1 1 2 2 2 0 MT0933-like antitoxin protein Entericidin PF08085.6 AEO62655.1 - 0.032 13.9 0.4 0.65 9.8 0.0 2.9 3 0 0 3 3 3 0 Entericidin EcnA/B family EBP PF05241.7 AEO62656.1 - 1.1e-66 223.5 0.9 1.3e-66 223.3 0.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein Nairovirus_M PF07948.6 AEO62657.1 - 0.39 8.7 3.2 0.56 8.2 2.2 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like DAP10 PF07213.6 AEO62657.1 - 3.9 7.3 6.7 12 5.7 1.3 2.6 1 1 0 2 2 2 0 DAP10 membrane protein DUF3402 PF11882.3 AEO62658.1 - 2.7e-152 507.5 0.0 3.6e-152 507.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 AEO62658.1 - 3.6e-74 249.2 0.0 5e-74 248.7 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein Suf PF05843.9 AEO62658.1 - 2 8.0 13.0 0.96 9.1 0.4 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF2011 PF09428.5 AEO62659.1 - 2.3e-22 79.2 26.5 7.3e-22 77.6 18.4 1.7 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) zf-HC2 PF13490.1 AEO62659.1 - 0.036 13.9 2.1 0.081 12.8 0.0 2.4 2 0 0 2 2 2 0 Putative zinc-finger Calici_MSP PF05752.6 AEO62659.1 - 0.11 12.0 1.5 0.47 10.0 1.0 2.0 1 1 0 1 1 1 0 Calicivirus minor structural protein RR_TM4-6 PF06459.7 AEO62659.1 - 0.32 10.8 5.0 0.54 10.1 3.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NDT80_PhoG PF05224.7 AEO62660.1 - 1.2e-15 57.9 0.0 1.9e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family RWD PF05773.17 AEO62662.1 - 4.3e-22 78.1 0.0 8.6e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 AEO62662.1 - 1.1e-20 73.2 36.0 5.8e-15 54.9 2.6 4.5 4 1 1 5 5 5 2 IBR domain zf-RING_UBOX PF13445.1 AEO62662.1 - 0.0089 15.7 1.4 0.0089 15.7 1.0 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AEO62662.1 - 0.014 15.2 1.3 0.014 15.2 0.9 4.3 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 AEO62662.1 - 6.4 6.5 37.2 0.041 13.5 4.6 4.4 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) PAP2 PF01569.16 AEO62663.1 - 4.4e-17 61.9 0.0 1.8e-16 59.9 0.0 1.9 2 1 0 2 2 2 1 PAP2 superfamily P12 PF12669.2 AEO62663.1 - 0.22 11.7 1.2 6.8 6.9 1.1 2.5 2 0 0 2 2 2 0 Virus attachment protein p12 family PrgI PF12666.2 AEO62663.1 - 0.93 9.6 3.6 1.1 9.4 0.1 2.5 3 0 0 3 3 3 0 PrgI family protein MARVEL PF01284.18 AEO62664.1 - 0.43 10.3 15.3 1.4 8.6 10.8 1.7 1 1 1 2 2 2 0 Membrane-associating domain DUF4233 PF14017.1 AEO62664.1 - 2.1 8.3 11.1 0.4 10.6 5.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) Chordopox_E11 PF06138.7 AEO62665.1 - 0.019 15.0 5.2 0.02 14.9 3.6 1.1 1 0 0 1 1 1 0 Chordopoxvirus E11 protein RVT_1 PF00078.22 AEO62665.1 - 0.025 13.9 0.3 0.025 13.9 0.2 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) WSC PF01822.14 AEO62666.1 - 3.2e-25 87.8 28.8 1.3e-18 66.6 7.1 3.2 3 0 0 3 3 3 2 WSC domain peroxidase PF00141.18 AEO62666.1 - 1e-20 74.2 0.0 1.9e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Peroxidase PAN_3 PF08277.7 AEO62666.1 - 0.93 9.1 7.6 0.67 9.6 0.6 3.5 4 0 0 4 4 4 0 PAN-like domain Fungal_trans PF04082.13 AEO62668.1 - 4.8e-33 114.1 0.0 7.7e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO62668.1 - 5.6e-07 29.3 9.2 1.1e-06 28.4 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GAS2 PF02187.12 AEO62669.1 - 5.1e-05 22.9 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Lipase_3 PF01764.20 AEO62670.1 - 3.3e-38 130.4 0.0 4.4e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 AEO62670.1 - 5.5e-06 26.4 0.4 7.3e-06 26.0 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO62670.1 - 0.00013 21.7 0.1 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 AEO62670.1 - 0.00082 18.8 0.7 0.16 11.3 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Lipase3_N PF03893.11 AEO62670.1 - 0.001 18.8 0.2 0.0021 17.8 0.2 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region PGAP1 PF07819.8 AEO62670.1 - 0.0013 18.4 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_8 PF06259.7 AEO62670.1 - 0.0014 18.1 0.1 0.0022 17.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase Thioesterase PF00975.15 AEO62670.1 - 0.0076 16.5 0.1 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 AEO62670.1 - 0.047 13.2 0.1 0.085 12.4 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold YjeF_N PF03853.10 AEO62670.1 - 0.19 11.3 0.7 0.33 10.5 0.5 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Glyco_hydro_3 PF00933.16 AEO62673.1 - 4.4e-74 249.1 0.0 6.2e-74 248.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO62673.1 - 5.7e-55 186.2 0.0 6.9e-54 182.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO62673.1 - 2.4e-23 81.8 0.3 4.5e-23 80.9 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.6 AEO62673.1 - 0.0018 18.2 0.0 0.0051 16.8 0.0 1.7 1 0 0 1 1 1 1 CARDB Ribosomal_L34 PF00468.12 AEO62674.1 - 1e-12 47.5 11.3 1.5e-12 46.9 7.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Peptidase_M48 PF01435.13 AEO62675.1 - 7.2e-50 169.6 0.0 1.2e-49 168.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 AEO62675.1 - 0.06 12.3 0.2 0.11 11.4 0.1 1.5 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF2201_N PF13203.1 AEO62675.1 - 0.22 10.6 0.9 0.31 10.1 0.1 1.6 2 0 0 2 2 2 0 Putative metallopeptidase domain Ish1 PF10281.4 AEO62676.1 - 3.2e-05 23.9 0.1 5e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein Metal_resist PF13801.1 AEO62676.1 - 0.024 14.6 0.2 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 Heavy-metal resistance SAP PF02037.22 AEO62676.1 - 0.059 12.9 0.0 0.52 9.8 0.0 2.0 2 0 0 2 2 2 0 SAP domain Ribosomal_L38e PF01781.13 AEO62677.1 - 1.2e-33 114.5 4.4 1.4e-33 114.4 3.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family CLTH PF10607.4 AEO62677.1 - 0.078 12.6 0.1 0.088 12.5 0.1 1.1 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain GHMP_kinases_N PF00288.21 AEO62678.1 - 2e-19 69.4 0.0 4.4e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AEO62678.1 - 2.1e-08 34.2 0.0 4.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 AEO62678.1 - 0.014 14.6 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature PPTA PF01239.17 AEO62679.1 - 2.3e-42 140.5 4.5 1.2e-07 30.7 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_8 PF13181.1 AEO62679.1 - 0.053 13.3 2.2 0.46 10.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat COX7a PF02238.10 AEO62680.1 - 0.37 10.5 1.9 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIa PGA2 PF07543.7 AEO62681.1 - 2.1e-43 147.4 1.0 2.4e-43 147.2 0.7 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 CENP-S PF15630.1 AEO62682.1 - 1.6e-35 121.1 0.0 2.1e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 AEO62682.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 AEO62682.1 - 0.014 14.6 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-18kDa PF02269.11 AEO62682.1 - 0.019 14.7 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TFIID-31kDa PF02291.10 AEO62682.1 - 0.041 13.6 0.0 0.058 13.1 0.0 1.3 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.5 AEO62682.1 - 0.19 11.5 0.8 1.6 8.6 0.0 2.7 4 0 0 4 4 4 0 Proto-chlorophyllide reductase 57 kD subunit WD40 PF00400.27 AEO62684.1 - 5.1e-65 213.2 20.2 5.3e-09 35.6 0.0 12.0 12 1 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.6 AEO62684.1 - 6.1e-45 152.3 0.0 1e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 AEO62684.1 - 6.1e-08 31.2 8.5 0.0026 15.9 0.1 5.6 3 2 1 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AEO62684.1 - 7.8e-07 28.1 0.9 0.18 10.5 0.0 4.6 5 1 0 5 5 5 3 Nup133 N terminal like DUF2510 PF10708.4 AEO62685.1 - 0.11 11.9 0.2 0.15 11.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2510) UCH PF00443.24 AEO62686.1 - 3.5e-22 78.7 0.0 5.2e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 AEO62686.1 - 2.4e-12 46.7 0.2 4.2e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 AEO62686.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase IF4E PF01652.13 AEO62687.1 - 1.3e-52 177.7 0.0 2e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Zip PF02535.17 AEO62687.1 - 2.4 7.0 4.2 3.1 6.7 2.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MTHFR PF02219.12 AEO62688.1 - 1.9e-99 332.4 0.0 2.6e-99 331.9 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase COX8 PF02285.10 AEO62689.1 - 0.54 9.8 2.0 0.83 9.2 1.4 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII DUF1617 PF07761.7 AEO62690.1 - 0.066 13.2 0.1 0.099 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) Nucleo_P87 PF07267.6 AEO62690.1 - 0.1 11.2 0.7 0.17 10.5 0.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PQ-loop PF04193.9 AEO62691.1 - 1e-18 66.6 2.8 8.2e-13 47.7 0.5 2.5 2 0 0 2 2 2 2 PQ loop repeat Zn_clus PF00172.13 AEO62693.1 - 4.4e-07 29.6 9.7 7.3e-07 28.9 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 AEO62694.1 - 3.6e-30 102.7 8.6 9.4e-07 28.4 1.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Glyco_transf_15 PF01793.11 AEO62695.1 - 8.4e-137 455.5 7.2 1e-136 455.2 5.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Spc97_Spc98 PF04130.8 AEO62696.1 - 1.4e-69 234.9 0.0 1.8e-69 234.5 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 AEO62696.1 - 0.015 13.4 0.0 0.027 12.6 0.0 1.5 1 1 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 DUF572 PF04502.8 AEO62697.1 - 1.7e-75 254.2 0.1 2e-75 254.0 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Gin PF10764.4 AEO62697.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin IncA PF04156.9 AEO62697.1 - 3.5 7.1 6.0 4.4 6.8 4.1 1.1 1 0 0 1 1 1 0 IncA protein PP28 PF10252.4 AEO62697.1 - 4.7 7.2 17.8 0.066 13.2 6.5 2.1 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Glyco_hydro_18 PF00704.23 AEO62699.1 - 6.9e-10 38.8 0.0 1.6e-09 37.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Herpes_gE PF02480.11 AEO62700.1 - 1.6e-05 23.3 0.0 2.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1049 PF06305.6 AEO62700.1 - 0.18 11.2 1.1 0.43 10.0 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) THRAP3_BCLAF1 PF15440.1 AEO62700.1 - 1.2 7.6 13.2 3.3 6.2 9.2 1.7 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF1996 PF09362.5 AEO62701.1 - 2.9e-77 259.4 0.3 3.8e-77 259.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PV_NSP1 PF12433.3 AEO62701.1 - 0.22 11.6 0.3 6.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Parvovirus non-structural protein 1 TPR_11 PF13414.1 AEO62703.1 - 4.3e-11 42.2 0.3 2.5e-09 36.6 0.0 2.8 2 0 0 2 2 2 1 TPR repeat UBA PF00627.26 AEO62703.1 - 1.7e-06 27.6 0.0 1.2e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain TPR_2 PF07719.12 AEO62703.1 - 5.4e-06 25.9 2.8 0.86 9.6 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 AEO62703.1 - 1.4e-05 24.4 0.1 0.13 11.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.26 AEO62703.1 - 0.0027 17.4 0.0 0.0066 16.1 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DUF630 PF04783.7 AEO62703.1 - 0.02 14.7 0.2 0.065 13.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF630) TPR_12 PF13424.1 AEO62703.1 - 0.081 12.8 5.0 0.1 12.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 AEO62703.1 - 0.19 12.4 7.0 3.5 8.4 0.1 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat UQ_con PF00179.21 AEO62704.1 - 4.4e-51 171.9 0.0 5e-51 171.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ammonium_transp PF00909.16 AEO62705.1 - 0.19 10.1 0.9 0.28 9.6 0.6 1.2 1 0 0 1 1 1 0 Ammonium Transporter Family LSM PF01423.17 AEO62706.1 - 4.7e-15 54.8 0.3 6.5e-15 54.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain TPPII_N PF12583.3 AEO62707.1 - 0.24 11.5 2.6 0.68 10.0 1.8 1.7 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal PAF-AH_p_II PF03403.8 AEO62708.1 - 6e-42 143.2 0.0 2.3e-36 124.9 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 AEO62708.1 - 4.9e-11 42.5 0.0 1.5e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 AEO62708.1 - 0.034 13.0 0.0 0.14 10.9 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 AEO62708.1 - 0.047 12.4 0.0 0.11 11.2 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase Peptidase_M18 PF02127.10 AEO62709.1 - 6.6e-124 413.7 0.0 7.6e-124 413.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) TMEM125 PF15109.1 AEO62709.1 - 0.089 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 TMEM125 protein family SPX PF03105.14 AEO62710.1 - 3e-57 194.4 0.0 8.8e-57 192.9 0.0 1.8 2 1 0 2 2 2 1 SPX domain EXS PF03124.9 AEO62710.1 - 2.1e-43 148.7 23.6 7.5e-22 77.8 5.2 2.1 1 1 1 2 2 2 2 EXS family FUR PF01475.14 AEO62710.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Ferric uptake regulator family CagE_TrbE_VirB PF03135.9 AEO62710.1 - 0.23 11.1 0.3 0.46 10.2 0.2 1.4 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system DUF883 PF05957.8 AEO62710.1 - 0.56 10.6 8.7 0.62 10.4 2.4 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) CAF1A PF12253.3 AEO62712.1 - 4.1e-23 81.2 1.5 4.1e-23 81.2 1.0 2.9 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A MIP-T3 PF10243.4 AEO62712.1 - 3.5e-05 22.4 30.6 6.5e-05 21.6 21.2 1.5 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CAF-1_p150 PF11600.3 AEO62712.1 - 0.00054 19.4 61.5 0.0031 16.9 41.9 2.3 1 1 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ycf1 PF05758.7 AEO62712.1 - 1 7.0 16.3 1.4 6.4 11.3 1.2 1 0 0 1 1 1 0 Ycf1 Peptidase_S64 PF08192.6 AEO62712.1 - 1.3 7.3 7.5 1.8 6.8 5.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 SET PF00856.23 AEO62712.1 - 1.8 8.8 5.5 1.3 9.3 2.3 1.9 2 0 0 2 2 2 0 SET domain SOBP PF15279.1 AEO62712.1 - 5.5 7.2 21.7 2.1 8.6 9.9 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein DUF966 PF06136.8 AEO62712.1 - 7.3 5.9 21.7 16 4.8 15.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Peptidase_M50B PF13398.1 AEO62713.1 - 3.6e-57 192.9 17.8 4.8e-57 192.5 12.4 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M41 PF01434.13 AEO62713.1 - 0.044 13.2 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M41 Na_Pi_cotrans PF02690.10 AEO62713.1 - 0.21 11.3 7.1 0.061 13.0 1.3 2.4 2 1 0 2 2 2 0 Na+/Pi-cotransporter Peptidase_M50 PF02163.17 AEO62713.1 - 1.2 8.0 8.0 0.24 10.3 2.7 2.1 2 1 0 2 2 2 0 Peptidase family M50 SecD_SecF PF02355.11 AEO62713.1 - 9.2 5.4 7.7 3.8 6.6 0.5 2.6 3 0 0 3 3 3 0 Protein export membrane protein Glyoxalase PF00903.20 AEO62714.1 - 8.1e-11 42.0 0.2 1e-10 41.6 0.2 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 AEO62714.1 - 7.4e-09 36.1 0.2 8.8e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 AEO62714.1 - 0.04 13.9 0.0 0.26 11.2 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF4613 PF15390.1 AEO62715.1 - 0.16 10.1 0.1 0.22 9.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Transp_cyt_pur PF02133.10 AEO62716.1 - 4.1e-38 131.0 36.4 2.9e-37 128.2 24.8 2.2 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DNA_ligase_A_M PF01068.16 AEO62717.1 - 2.8e-23 82.3 0.0 4.9e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 AEO62717.1 - 1.5e-11 44.4 0.0 2.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DUF1115 PF06544.7 AEO62718.1 - 0.044 13.4 0.1 0.42 10.2 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1115) FLILHELTA PF10306.4 AEO62719.1 - 9.3e-29 99.3 0.0 1.3e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 AEO62719.1 - 0.0033 17.7 0.1 0.0055 16.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) NDK PF00334.14 AEO62723.1 - 4e-55 185.3 0.0 4.5e-55 185.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.21 AEO62724.1 - 9.2e-154 512.4 3.6 1.2e-153 512.1 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 AEO62724.1 - 5.6e-24 83.7 0.2 2.3e-23 81.8 0.1 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like Peptidase_A4 PF01828.12 AEO62725.1 - 1e-21 76.9 4.0 5.5e-13 48.4 0.0 2.6 2 1 0 2 2 2 2 Peptidase A4 family APH PF01636.18 AEO62728.1 - 2.9e-17 63.2 0.5 1.1e-16 61.2 0.3 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 AEO62728.1 - 0.023 14.0 1.0 0.8 9.0 0.1 2.4 3 0 0 3 3 3 0 RIO1 family Choline_kinase PF01633.15 AEO62728.1 - 0.024 14.2 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase GCD14 PF08704.5 AEO62729.1 - 5.8e-65 219.2 0.0 1.4e-47 162.3 0.0 2.7 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 AEO62729.1 - 3.8e-05 23.7 0.0 9.7e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO62729.1 - 0.00019 21.9 0.1 0.00064 20.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DIOX_N PF14226.1 AEO62730.1 - 1.8e-23 83.2 0.0 2.6e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 AEO62730.1 - 1e-10 41.7 0.0 7.9e-10 38.9 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sec39 PF08314.6 AEO62732.1 - 1.3e-228 760.5 0.0 1.5e-228 760.3 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.4 AEO62733.1 - 0.00034 20.5 0.0 0.00044 20.1 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.8 AEO62733.1 - 0.0093 15.8 0.5 0.02 14.8 0.4 1.6 1 1 0 1 1 1 1 CHCH domain COX6B PF02297.12 AEO62733.1 - 0.015 15.3 0.2 0.023 14.7 0.1 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb UCR_hinge PF02320.11 AEO62733.1 - 0.021 14.7 0.3 0.033 14.1 0.2 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein DUF3128 PF11326.3 AEO62733.1 - 0.21 11.7 1.2 0.58 10.3 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) NAD_binding_1 PF00175.16 AEO62735.1 - 0.00029 21.3 0.0 0.25 11.9 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 AEO62735.1 - 0.026 14.4 0.1 0.18 11.6 0.0 1.9 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Peptidase_C48 PF02902.14 AEO62736.1 - 9.7e-33 113.6 0.0 1.8e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain WD40 PF00400.27 AEO62737.1 - 5.1e-27 92.7 2.5 2.4e-07 30.3 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 AEO62737.1 - 0.029 12.5 0.2 1.1 7.3 0.1 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 CAML PF14963.1 AEO62737.1 - 7.6 5.8 5.9 6 6.1 3.0 1.6 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Proteasome PF00227.21 AEO62738.1 - 2.1e-36 125.0 0.0 2.4e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DEAD PF00270.24 AEO62739.1 - 3.7e-47 159.9 0.0 1.5e-45 154.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO62739.1 - 6.1e-29 99.7 0.0 1.2e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO62739.1 - 0.029 14.1 0.0 0.069 12.9 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1253 PF06862.7 AEO62739.1 - 0.068 11.5 0.0 0.13 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 AEO62739.1 - 0.16 10.9 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ORC2 PF04084.9 AEO62740.1 - 1.9e-81 273.4 0.0 2.3e-81 273.1 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 PGP_phosphatase PF09419.5 AEO62741.1 - 2.1e-65 219.2 0.0 2.4e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 AEO62741.1 - 0.00024 20.7 0.1 0.00049 19.7 0.1 1.5 1 1 0 1 1 1 1 HAD-hyrolase-like Zn_Tnp_IS91 PF14319.1 AEO62742.1 - 0.059 12.8 0.6 0.1 12.1 0.4 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain DUF4189 PF13827.1 AEO62742.1 - 0.17 12.1 4.0 0.31 11.3 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4189) Methyltransf_23 PF13489.1 AEO62743.1 - 4e-19 68.9 0.0 7e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO62743.1 - 8.8e-08 31.8 0.0 0.007 15.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 AEO62743.1 - 8e-07 29.4 0.0 1.7e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO62743.1 - 1.7e-06 28.4 0.0 5.6e-05 23.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO62743.1 - 2.8e-06 27.8 0.0 0.00014 22.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO62743.1 - 0.00068 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 AEO62743.1 - 0.0035 17.3 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 AEO62743.1 - 0.0052 17.1 0.0 0.024 15.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AEO62743.1 - 0.018 14.6 0.0 0.71 9.3 0.0 2.1 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 AEO62743.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 AEO62743.1 - 0.11 11.4 1.0 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_26 PF13659.1 AEO62743.1 - 0.11 12.4 0.0 0.23 11.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 AEO62743.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPR_2 PF07719.12 AEO62744.1 - 3.3e-24 82.7 26.8 0.001 18.7 0.8 10.7 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_11 PF13414.1 AEO62744.1 - 1.5e-23 82.1 26.6 3e-08 33.1 0.1 8.2 4 2 4 8 8 8 7 TPR repeat Apc3 PF12895.2 AEO62744.1 - 2.3e-23 82.1 17.3 2.5e-18 65.9 0.6 6.0 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 AEO62744.1 - 1.3e-22 79.9 17.6 0.00085 19.6 0.7 9.2 7 3 1 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.23 AEO62744.1 - 2.7e-22 77.3 12.4 9.4e-05 21.8 1.1 9.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 AEO62744.1 - 9.5e-16 56.8 33.9 0.004 17.6 0.2 10.7 7 2 5 12 12 11 5 Tetratricopeptide repeat TPR_12 PF13424.1 AEO62744.1 - 1.1e-14 54.0 30.3 1.7e-07 31.0 1.1 8.0 4 3 5 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 AEO62744.1 - 4e-13 48.1 0.5 0.003 17.2 0.5 7.6 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO62744.1 - 2.1e-12 47.3 41.6 5.5e-06 26.9 4.9 9.2 7 3 3 10 10 9 5 Tetratricopeptide repeat TPR_7 PF13176.1 AEO62744.1 - 1e-08 34.3 17.4 0.7 9.8 0.1 8.7 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_10 PF13374.1 AEO62744.1 - 2.5e-08 33.5 12.5 0.013 15.4 0.1 6.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 AEO62744.1 - 1.7e-06 27.2 10.6 0.0042 16.1 0.0 5.3 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 AEO62744.1 - 0.00012 22.2 17.9 0.6 10.6 0.4 8.7 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 AEO62744.1 - 0.00093 19.2 7.5 27 5.3 0.0 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat Coatomer_E PF04733.9 AEO62744.1 - 0.0014 17.8 1.8 0.97 8.5 0.0 3.8 4 0 0 4 4 4 1 Coatomer epsilon subunit TPR_5 PF12688.2 AEO62744.1 - 0.043 13.8 0.5 0.043 13.8 0.3 2.4 2 0 0 2 2 1 0 Tetratrico peptide repeat TPR_20 PF14561.1 AEO62744.1 - 0.2 11.7 5.5 7.1 6.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 AEO62744.1 - 0.29 11.6 0.1 0.29 11.6 0.1 8.0 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_9 PF13371.1 AEO62744.1 - 2.7 7.9 23.7 1.5 8.7 2.8 5.3 5 1 1 6 6 5 0 Tetratricopeptide repeat IATP PF04568.7 AEO62744.1 - 2.8 8.0 6.5 8.5 6.4 4.5 1.8 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP TPR_21 PF09976.4 AEO62744.1 - 4.1 7.3 11.3 31 4.5 0.1 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat AMP-binding PF00501.23 AEO62745.1 - 5.9e-50 169.8 0.2 8.8e-50 169.2 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO62745.1 - 0.0021 18.9 0.0 0.0049 17.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAT PF02259.18 AEO62746.1 - 3.9e-75 253.0 4.9 7.2e-75 252.1 3.4 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 AEO62746.1 - 2.2e-25 89.5 0.4 1e-24 87.3 0.1 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 AEO62746.1 - 7.6e-08 31.6 0.1 7.6e-08 31.6 0.1 2.1 2 0 0 2 2 2 1 FATC domain Urb2 PF10441.4 AEO62746.1 - 0.0036 16.9 2.3 0.32 10.5 0.1 3.3 3 0 0 3 3 3 1 Urb2/Npa2 family TPR_8 PF13181.1 AEO62746.1 - 0.011 15.4 1.2 0.072 12.8 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 AEO62746.1 - 0.014 15.2 0.8 8.4 6.5 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Glycolytic PF00274.14 AEO62746.1 - 0.15 10.4 0.0 0.26 9.6 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I TPR_12 PF13424.1 AEO62746.1 - 0.25 11.2 3.9 3.2 7.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Chitin_bind_3 PF03067.10 AEO62747.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Chitin binding domain AIG2 PF06094.7 AEO62748.1 - 3.3e-19 69.2 0.5 4.7e-19 68.7 0.3 1.2 1 0 0 1 1 1 1 AIG2-like family UPF0029 PF01205.14 AEO62749.1 - 7.2e-31 106.1 0.0 1.2e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 AEO62749.1 - 1.9e-10 40.6 0.0 3.2e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain ACT_7 PF13840.1 AEO62750.1 - 1.8e-22 78.6 1.8 5.9e-18 64.1 0.1 2.8 3 0 0 3 3 3 2 ACT domain Methyltransf_32 PF13679.1 AEO62751.1 - 7.2e-19 67.8 0.0 3.4e-18 65.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ribosomal_S13 PF00416.17 AEO62752.1 - 4.2e-21 75.4 0.1 4.7e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Virul_Fac PF10139.4 AEO62752.1 - 0.051 11.5 0.0 0.055 11.3 0.0 1.0 1 0 0 1 1 1 0 Putative bacterial virulence factor Peptidase_M19 PF01244.16 AEO62753.1 - 2.7e-102 341.9 0.0 3.1e-102 341.7 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) FCH PF00611.18 AEO62754.1 - 1.5e-16 60.3 0.6 1.5e-15 57.1 0.0 2.7 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 AEO62754.1 - 2.7e-14 52.6 0.0 6.1e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.22 AEO62754.1 - 1.9e-13 50.3 0.1 7.6e-13 48.3 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain RVT_1 PF00078.22 AEO62755.1 - 5.3e-08 32.4 0.0 1.3e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DHC_N2 PF08393.8 AEO62755.1 - 0.19 10.1 2.4 0.11 10.9 0.2 1.7 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 MARVEL PF01284.18 AEO62756.1 - 0.00015 21.5 17.4 0.00023 20.9 12.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain Nop16 PF09420.5 AEO62757.1 - 5.9e-53 179.3 6.5 8e-53 178.8 4.5 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 CDC45 PF02724.9 AEO62757.1 - 1.7 6.5 6.1 2.8 5.8 4.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Fungal_trans_2 PF11951.3 AEO62758.1 - 2.5e-47 161.3 0.2 8.3e-29 100.3 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO62758.1 - 5e-07 29.5 6.9 1.2e-06 28.3 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RVT_1 PF00078.22 AEO62759.1 - 0.0059 15.9 0.1 0.0062 15.9 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 AEO62760.1 - 0.14 12.2 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain GSHPx PF00255.14 AEO62761.1 - 7e-43 144.4 0.1 8.7e-43 144.1 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 AEO62761.1 - 1.9e-05 24.3 0.0 3.2e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.1 AEO62761.1 - 0.00014 21.9 0.0 0.00016 21.7 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4174) Redoxin PF08534.5 AEO62761.1 - 0.0002 20.8 0.1 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin DAO PF01266.19 AEO62762.1 - 4.7e-57 193.5 3.7 6.2e-56 189.8 2.6 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO62762.1 - 7.8e-06 26.2 0.1 0.0064 16.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO62762.1 - 2.3e-05 24.3 0.3 5.3e-05 23.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 AEO62762.1 - 0.0016 17.1 1.0 0.0027 16.4 0.2 1.6 2 0 0 2 2 2 1 Tryptophan halogenase GMC_oxred_N PF00732.14 AEO62762.1 - 0.0017 17.5 0.2 0.92 8.5 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 AEO62762.1 - 0.0027 16.6 2.3 0.8 8.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 AEO62762.1 - 0.0044 16.9 0.3 1.3 8.8 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 AEO62762.1 - 0.011 13.8 0.0 1.9 6.5 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.12 AEO62762.1 - 0.044 12.8 0.1 0.076 12.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DHDPS PF00701.17 AEO62763.1 - 8.7e-36 123.0 0.0 1e-35 122.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.17 AEO62764.1 - 2e-09 37.9 1.1 9.2e-09 35.8 0.7 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.11 AEO62765.1 - 2e-30 105.7 34.2 2e-30 105.7 23.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO62765.1 - 7.6e-06 24.7 5.1 7.6e-06 24.7 3.5 3.4 1 1 1 3 3 3 1 Sugar (and other) transporter CcmD PF04995.9 AEO62765.1 - 0.96 9.2 0.0 0.96 9.2 0.0 4.0 4 0 0 4 4 4 0 Heme exporter protein D (CcmD) TIMELESS PF04821.9 AEO62766.1 - 3.8e-94 314.8 0.3 1.9e-93 312.5 0.0 2.2 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.8 AEO62766.1 - 1.8e-39 136.1 0.3 1.8e-39 136.1 0.2 4.0 3 1 1 4 4 4 1 Timeless protein C terminal region 3HCDH_N PF02737.13 AEO62767.1 - 2.2e-51 174.0 0.8 3.2e-51 173.5 0.6 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 AEO62767.1 - 7.6e-34 116.0 0.0 1.5e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 AEO62767.1 - 0.0025 17.6 0.1 0.0054 16.5 0.1 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 AEO62767.1 - 0.0064 15.6 0.2 0.016 14.4 0.1 1.6 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 AEO62767.1 - 0.0064 15.4 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 AEO62767.1 - 0.008 15.6 0.2 0.029 13.8 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 AEO62767.1 - 0.067 13.2 1.2 0.17 11.9 0.4 1.8 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 AEO62767.1 - 0.077 13.4 1.2 0.34 11.3 0.8 2.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 AEO62767.1 - 0.099 13.0 0.1 0.36 11.2 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Homeobox PF00046.24 AEO62768.1 - 5.9e-14 51.4 0.2 1.1e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 AEO62768.1 - 0.0022 17.6 0.1 0.0055 16.3 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain HCO3_cotransp PF00955.16 AEO62771.1 - 2.3e-67 227.8 13.0 5.3e-40 137.5 1.7 3.0 2 1 1 3 3 3 3 HCO3- transporter family Peptidase_M41 PF01434.13 AEO62772.1 - 6.7e-76 254.4 0.0 9.9e-76 253.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 AEO62772.1 - 6.7e-43 146.0 0.0 1.5e-42 144.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 AEO62772.1 - 2.9e-13 49.9 0.0 6.1e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.1 AEO62772.1 - 0.002 18.2 0.1 0.11 12.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO62772.1 - 0.003 17.2 0.1 0.012 15.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 AEO62772.1 - 0.0049 16.6 0.4 0.017 14.8 0.3 1.9 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 AEO62772.1 - 0.012 14.6 0.8 0.028 13.4 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 AEO62772.1 - 0.012 14.3 0.1 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_14 PF13173.1 AEO62772.1 - 0.018 14.9 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 AEO62772.1 - 0.019 14.8 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 AEO62772.1 - 0.025 14.0 0.0 0.056 12.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 AEO62772.1 - 0.025 14.5 2.9 0.13 12.2 0.1 3.2 4 1 1 5 5 5 0 AAA ATPase domain AAA_17 PF13207.1 AEO62772.1 - 0.026 15.3 0.0 0.13 13.0 0.0 2.3 2 1 0 2 2 1 0 AAA domain AAA_25 PF13481.1 AEO62772.1 - 0.045 13.1 1.2 0.14 11.5 0.1 2.2 2 1 1 3 3 3 0 AAA domain Cytochrom_C PF00034.16 AEO62772.1 - 0.063 14.1 4.1 0.48 11.2 0.0 2.8 2 0 0 2 2 2 0 Cytochrome c Pex14_N PF04695.8 AEO62772.1 - 6 6.9 10.4 1 9.4 3.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Fungal_trans PF04082.13 AEO62773.1 - 3.7e-30 104.6 0.0 1.1e-29 103.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO62773.1 - 5.4e-10 39.0 12.2 9.1e-10 38.2 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 AEO62773.1 - 0.025 14.0 21.8 0.028 13.8 6.6 2.2 2 0 0 2 2 2 0 Vta1 like Dicty_REP PF05086.7 AEO62773.1 - 5.1 4.7 7.2 8.3 4.0 5.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pyr_redox_2 PF07992.9 AEO62774.1 - 1.2e-13 51.4 0.0 2.8e-13 50.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO62774.1 - 8.3e-09 35.7 0.2 0.0002 21.6 0.2 3.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AEO62774.1 - 7.2e-08 31.7 1.3 0.018 13.9 0.1 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 AEO62774.1 - 3.8e-06 26.7 0.1 0.56 9.9 0.0 3.5 3 0 0 3 3 3 3 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 AEO62774.1 - 1.2e-05 24.3 0.1 0.015 14.2 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein K_oxygenase PF13434.1 AEO62774.1 - 2.8e-05 23.1 0.1 0.00035 19.6 0.1 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 AEO62774.1 - 7e-05 22.9 0.2 0.036 14.1 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 AEO62774.1 - 0.012 15.5 0.0 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_8 PF13450.1 AEO62774.1 - 0.068 13.2 0.1 2 8.5 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 AEO62774.1 - 0.091 11.8 0.1 12 4.8 0.0 2.3 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 AEO62774.1 - 0.16 10.8 1.7 12 4.6 0.0 3.2 4 0 0 4 4 4 0 Glucose inhibited division protein A Fungal_trans PF04082.13 AEO62775.1 - 1.6e-12 46.8 0.0 2.6e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO62775.1 - 3.2e-09 36.5 10.5 6.1e-09 35.6 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mid2 PF04478.7 AEO62776.1 - 0.0034 16.8 0.0 0.0034 16.8 0.0 2.3 2 1 1 3 3 3 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.10 AEO62776.1 - 0.011 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 BAF1_ABF1 PF04684.8 AEO62776.1 - 0.27 10.0 13.9 0.39 9.5 9.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF676 PF05057.9 AEO62777.1 - 1.5e-08 34.2 0.1 2.4e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 AEO62777.1 - 1.1e-06 28.4 0.1 4.6e-06 26.3 0.1 1.9 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 AEO62777.1 - 9.3e-06 25.4 0.0 2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO62777.1 - 0.00024 21.0 1.9 0.00024 21.0 1.3 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family UPF0227 PF05728.7 AEO62777.1 - 0.00039 20.1 0.2 0.00085 19.0 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.20 AEO62777.1 - 0.012 15.1 0.5 0.045 13.3 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_3 PF07859.8 AEO62777.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 AEO62777.1 - 0.098 12.8 0.3 0.59 10.3 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain Rox3 PF08633.5 AEO62778.1 - 3.1e-58 197.2 0.2 3.9e-57 193.6 0.0 2.0 2 0 0 2 2 2 1 Rox3 mediator complex subunit Ribosomal_L4 PF00573.17 AEO62779.1 - 2.2e-47 160.9 0.0 3.3e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DUF742 PF05331.6 AEO62779.1 - 0.029 13.9 0.1 0.051 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF742) PBP PF01161.15 AEO62780.1 - 5.3e-11 42.5 0.0 8.3e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Trans_reg_C PF00486.23 AEO62781.1 - 0.054 13.4 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal RhoGAP PF00620.22 AEO62782.1 - 1.1e-09 38.0 0.0 2.5e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 RhoGAP domain CBS PF00571.23 AEO62783.1 - 2e-32 110.7 8.8 4.6e-15 55.1 0.2 4.3 4 0 0 4 4 4 4 CBS domain Arm PF00514.18 AEO62784.1 - 8.2e-71 231.6 30.5 2.1e-12 46.3 0.3 10.8 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 AEO62784.1 - 2.7e-23 82.0 12.9 2.1e-05 24.7 0.1 7.2 3 3 2 6 6 6 6 HEAT repeats HEAT PF02985.17 AEO62784.1 - 2.5e-19 67.5 12.4 0.012 15.6 0.1 9.1 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 AEO62784.1 - 4e-16 58.9 12.9 0.00026 21.3 0.1 8.0 4 1 4 8 8 8 4 HEAT-like repeat Adaptin_N PF01602.15 AEO62784.1 - 2e-10 39.6 9.1 4.8e-06 25.1 1.9 2.9 2 1 1 3 3 3 2 Adaptin N terminal region V-ATPase_H_N PF03224.9 AEO62784.1 - 3.5e-10 39.4 0.9 0.00082 18.5 0.2 3.9 2 1 1 3 3 3 2 V-ATPase subunit H Arm_2 PF04826.8 AEO62784.1 - 1.8e-08 33.8 7.8 1.2e-05 24.5 2.5 3.1 1 1 2 3 3 3 3 Armadillo-like KAP PF05804.7 AEO62784.1 - 3.5e-08 31.8 0.8 5.6e-08 31.1 0.5 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) HEAT_PBS PF03130.11 AEO62784.1 - 0.00029 21.0 4.8 60 4.5 0.0 7.0 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat DUF908 PF06012.7 AEO62784.1 - 0.00042 19.7 3.3 1.3 8.2 0.1 3.8 3 1 0 4 4 4 2 Domain of Unknown Function (DUF908) Vpu PF00558.14 AEO62784.1 - 0.0089 15.5 0.1 0.0089 15.5 0.1 2.2 3 0 0 3 3 3 1 Vpu protein Peptidase_S24 PF00717.18 AEO62785.1 - 4.7e-08 32.5 0.0 1.3e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 AEO62785.1 - 1.4e-06 27.8 0.0 2.9e-05 23.6 0.0 2.5 2 1 0 2 2 2 1 Signal peptidase, peptidase S26 IF3_C PF00707.17 AEO62786.1 - 4.1e-11 42.4 0.0 6.4e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 AEO62786.1 - 0.024 14.0 0.1 0.11 11.9 0.0 1.8 1 1 1 2 2 2 0 Mitochondrial translation initiation factor IF-2B PF01008.12 AEO62787.1 - 1.1e-44 152.5 0.0 2.5e-44 151.3 0.0 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family COMPASS-Shg1 PF05205.7 AEO62789.1 - 9.6e-27 93.3 0.2 2.5e-26 92.0 0.1 1.7 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 TPT PF03151.11 AEO62790.1 - 3.8e-28 98.0 14.8 3.8e-28 98.0 10.3 2.9 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 AEO62790.1 - 4.3e-08 32.4 19.8 1.4e-06 27.4 13.7 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 AEO62790.1 - 2.4e-07 30.8 32.3 6.9e-06 26.1 5.5 2.6 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 AEO62790.1 - 0.52 9.0 17.9 2.7 6.7 12.3 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 AEO62790.1 - 6.9 6.9 28.5 0.13 12.4 5.2 3.2 3 1 0 3 3 3 0 Multidrug resistance efflux transporter UCH PF00443.24 AEO62791.1 - 1.4e-36 125.9 0.0 2e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO62791.1 - 0.0096 15.3 0.0 0.032 13.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2387 PF09526.5 AEO62791.1 - 0.25 11.3 1.0 30 4.6 0.1 2.6 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Alb1 PF09135.6 AEO62792.1 - 7.1e-28 97.4 11.5 7.1e-28 97.4 8.0 1.4 2 0 0 2 2 2 1 Alb1 Z1 PF10593.4 AEO62792.1 - 0.15 11.2 1.3 0.2 10.8 0.9 1.1 1 0 0 1 1 1 0 Z1 domain bZIP_1 PF00170.16 AEO62793.1 - 3.8e-08 33.1 6.9 7.7e-08 32.1 4.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AEO62793.1 - 1.3e-07 31.2 5.4 2.3e-07 30.5 3.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Rep_fac-A_3 PF08661.6 AEO62794.1 - 1.6e-21 76.2 0.0 1.8e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 tRNA_anti-like PF12869.2 AEO62794.1 - 0.021 14.2 0.1 0.03 13.8 0.1 1.2 1 0 0 1 1 1 0 tRNA_anti-like GATA PF00320.22 AEO62795.1 - 0.00091 18.5 5.5 0.058 12.7 1.6 2.4 2 0 0 2 2 2 2 GATA zinc finger Pyr_redox_2 PF07992.9 AEO62796.1 - 1.2e-14 54.6 0.0 1.5e-10 41.2 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO62796.1 - 6.3e-13 48.9 1.4 1.6e-10 41.2 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO62796.1 - 4.2e-08 33.4 2.5 1.9e-06 28.1 0.1 3.0 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO62796.1 - 0.00011 21.2 0.7 0.00061 18.8 0.1 2.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 AEO62796.1 - 0.031 13.1 2.8 7.2 5.4 0.1 3.5 3 1 0 4 4 4 0 FAD dependent oxidoreductase Malic_M PF03949.10 AEO62796.1 - 0.042 13.3 1.3 1.4 8.3 0.0 3.1 3 0 0 3 3 3 0 Malic enzyme, NAD binding domain TrkA_N PF02254.13 AEO62796.1 - 0.099 12.6 0.8 4.7 7.2 0.2 2.7 2 1 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.1 AEO62796.1 - 0.12 12.0 3.0 3.8 7.2 0.0 3.5 2 2 2 4 4 4 0 FAD-NAD(P)-binding PBP PF01161.15 AEO62797.1 - 2.6e-14 53.3 0.0 3.3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ER-remodelling PF14755.1 AEO62798.1 - 0.5 10.4 8.4 0.45 10.5 4.8 1.6 1 1 0 1 1 1 0 Intracellular membrane remodeller Peptidase_M14 PF00246.19 AEO62799.1 - 1.2e-72 244.8 0.0 1.6e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 AEO62799.1 - 0.11 11.4 0.0 4.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family Sec7 PF01369.15 AEO62800.1 - 4.8e-40 137.2 0.0 8.1e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 AEO62800.1 - 6.7e-05 23.0 0.0 0.00016 21.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 AEO62800.1 - 0.0032 17.6 0.0 0.0068 16.5 0.0 1.6 1 0 0 1 1 1 1 PH domain SRP72 PF08492.7 AEO62801.1 - 2.9e-16 59.5 9.8 2.9e-16 59.5 6.8 1.9 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.1 AEO62801.1 - 2.4e-05 24.1 19.7 0.0089 15.9 0.1 6.0 3 2 5 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 AEO62801.1 - 0.025 14.6 8.5 4.1 7.6 0.8 4.7 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AEO62801.1 - 0.03 14.1 0.2 0.03 14.1 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 AEO62801.1 - 0.069 13.4 30.5 1.3 9.4 0.0 7.0 5 3 2 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO62801.1 - 0.073 12.7 2.3 5.9 6.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 AEO62801.1 - 0.18 12.5 48.4 0.98 10.1 5.7 7.8 5 4 3 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO62801.1 - 0.39 11.4 0.0 0.39 11.4 0.0 10.0 8 2 2 10 10 10 0 Tetratricopeptide repeat TPR_4 PF07721.9 AEO62801.1 - 2.2 8.9 23.5 1.4 9.5 0.1 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat RVT_1 PF00078.22 AEO62802.1 - 0.014 14.7 0.5 0.017 14.4 0.4 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Abhydrolase_6 PF12697.2 AEO62803.1 - 3.4e-33 115.4 0.1 6.3e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO62803.1 - 1.3e-20 73.9 0.0 4.6e-20 72.1 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO62803.1 - 1.3e-14 54.2 0.0 3.3e-14 52.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 AEO62803.1 - 7.5e-08 32.8 0.0 1e-07 32.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 AEO62803.1 - 0.0001 21.9 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 AEO62803.1 - 0.0039 16.6 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 AEO62803.1 - 0.01 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Ser_hydrolase PF06821.8 AEO62803.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase DLH PF01738.13 AEO62803.1 - 0.14 11.3 0.0 1.3 8.2 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family Ribosomal_S3Ae PF01015.13 AEO62804.1 - 1.3e-80 269.3 3.5 1.5e-80 269.0 2.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Syntaxin PF00804.20 AEO62804.1 - 0.019 15.0 0.3 0.13 12.4 0.0 2.3 2 1 1 3 3 3 0 Syntaxin GTP_CH_N PF12471.3 AEO62806.1 - 1.4e-92 308.6 0.0 1.9e-92 308.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 AEO62806.1 - 1.4e-08 34.2 0.0 2.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Exonuc_V_gamma PF04257.9 AEO62807.1 - 0.0016 16.5 0.6 0.0017 16.4 0.4 1.1 1 0 0 1 1 1 1 Exodeoxyribonuclease V, gamma subunit RVT_1 PF00078.22 AEO62807.1 - 0.042 13.1 0.7 0.054 12.8 0.5 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Elf1 PF05129.8 AEO62808.1 - 4.9e-29 99.8 0.6 5.3e-29 99.7 0.4 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.10 AEO62808.1 - 0.006 16.1 3.4 0.077 12.5 0.1 2.2 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Ribosomal_L37ae PF01780.14 AEO62808.1 - 0.064 13.1 0.2 0.079 12.8 0.2 1.2 1 0 0 1 1 1 0 Ribosomal L37ae protein family zf-CHY PF05495.7 AEO62808.1 - 0.14 12.3 0.9 0.16 12.1 0.3 1.3 1 1 0 1 1 1 0 CHY zinc finger zf-ribbon_3 PF13248.1 AEO62808.1 - 0.14 11.4 0.7 0.32 10.2 0.5 1.6 1 1 0 1 1 1 0 zinc-ribbon domain Cys_rich_CPXG PF14255.1 AEO62808.1 - 0.14 11.9 0.7 0.3 10.9 0.5 1.6 1 1 0 1 1 1 0 Cysteine-rich CPXCG Zn_Tnp_IS1595 PF12760.2 AEO62808.1 - 0.17 11.6 1.0 0.35 10.7 0.7 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Cys_rich_CWC PF14375.1 AEO62808.1 - 0.2 11.5 1.7 0.27 11.1 0.3 1.8 2 0 0 2 2 2 0 Cysteine-rich CWC zf-C2H2_6 PF13912.1 AEO62808.1 - 2.2 8.2 5.6 2.6 8.0 0.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger UPRTase PF14681.1 AEO62809.1 - 1.5e-80 269.2 0.0 2e-80 268.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 AEO62809.1 - 4.7e-05 23.1 0.0 7.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 AEO62809.1 - 0.098 12.3 0.2 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) WAPL PF07814.8 AEO62810.1 - 8.3e-19 67.5 1.2 6.4e-18 64.6 0.9 2.1 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Ras PF00071.17 AEO62811.1 - 2.4e-46 157.0 0.1 2.8e-46 156.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO62811.1 - 1.1e-14 54.9 0.1 1.4e-14 54.5 0.1 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO62811.1 - 7.8e-08 31.7 0.0 9.1e-08 31.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 AEO62811.1 - 5.6e-06 26.3 0.0 9.8e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AEO62811.1 - 3.6e-05 23.2 0.1 0.00027 20.4 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 AEO62811.1 - 0.00055 19.2 0.0 0.0012 18.0 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 AEO62811.1 - 0.06 13.2 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain tRNA-synt_2b PF00587.20 AEO62812.1 - 3.2e-35 121.2 0.0 5.9e-35 120.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 AEO62812.1 - 3.2e-18 65.7 6.8 6.1e-18 64.8 4.7 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Peptidase_C78 PF07910.8 AEO62814.1 - 1.5e-66 223.7 0.0 2e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C47 PF05543.8 AEO62814.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Staphopain peptidase C47 zf-Di19 PF05605.7 AEO62814.1 - 0.57 10.3 3.4 1.4 9.0 0.0 2.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Ham1p_like PF01725.11 AEO62815.1 - 5.4e-53 179.1 0.0 6.2e-53 178.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 AEO62816.1 - 6.3e-29 100.8 1.8 1.6e-28 99.6 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 AEO62816.1 - 4.8e-17 62.9 1.4 9.3e-17 61.9 1.0 1.6 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 AEO62816.1 - 5.5e-06 26.3 0.1 0.0052 16.6 0.0 2.3 1 1 0 2 2 2 2 Adenylate kinase AAA_33 PF13671.1 AEO62816.1 - 2.2e-05 24.3 0.1 0.003 17.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 AEO62816.1 - 6.5e-05 22.9 0.1 0.00022 21.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 AEO62816.1 - 0.00025 21.2 0.0 0.00082 19.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 AEO62816.1 - 0.00037 20.3 0.9 0.0027 17.5 0.6 1.9 1 1 0 1 1 1 1 Shikimate kinase Thymidylate_kin PF02223.12 AEO62816.1 - 0.0013 18.1 0.2 0.57 9.5 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Cytidylate_kin2 PF13189.1 AEO62816.1 - 0.012 15.4 0.3 0.03 14.2 0.2 2.0 1 1 0 1 1 1 0 Cytidylate kinase-like family KTI12 PF08433.5 AEO62816.1 - 0.013 14.7 0.1 0.051 12.7 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 AEO62816.1 - 0.014 15.4 0.0 0.031 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 AEO62816.1 - 0.022 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 AEO62816.1 - 0.025 14.7 0.2 0.035 14.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 AEO62816.1 - 0.034 13.8 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 AEO62816.1 - 0.043 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.17 AEO62816.1 - 0.069 13.3 0.1 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 RNA helicase Myosin_head PF00063.16 AEO62817.1 - 3.3e-243 808.7 0.0 3.3e-243 808.7 0.0 1.7 2 0 0 2 2 1 1 Myosin head (motor domain) DIL PF01843.14 AEO62817.1 - 1e-34 118.5 3.5 2.6e-34 117.2 2.4 1.7 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 AEO62817.1 - 8.1e-14 49.8 42.9 0.0001 21.5 1.5 6.9 6 0 0 6 6 6 6 IQ calmodulin-binding motif ERM PF00769.14 AEO62817.1 - 0.00051 19.6 20.3 0.00051 19.6 14.1 3.1 3 0 0 3 3 3 1 Ezrin/radixin/moesin family GAS PF13851.1 AEO62817.1 - 0.0021 17.3 28.9 0.01 15.0 17.8 2.7 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 AEO62817.1 - 0.0022 17.2 2.7 0.0029 16.8 1.0 1.7 1 1 1 2 2 2 1 Reovirus sigma C capsid protein AAA_22 PF13401.1 AEO62817.1 - 0.003 17.7 0.0 0.013 15.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain FlaC_arch PF05377.6 AEO62817.1 - 0.0044 16.8 0.2 0.0044 16.8 0.1 3.7 5 0 0 5 5 3 1 Flagella accessory protein C (FlaC) DUF218 PF02698.12 AEO62817.1 - 0.0083 15.6 0.7 0.36 10.2 0.0 2.6 2 0 0 2 2 2 1 DUF218 domain AAA_10 PF12846.2 AEO62817.1 - 0.012 15.1 0.4 0.16 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain Myosin_N PF02736.14 AEO62817.1 - 0.024 14.2 1.2 0.058 13.0 0.8 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 AEO62817.1 - 0.029 14.1 0.0 0.11 12.2 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 AEO62817.1 - 0.03 14.3 2.1 0.26 11.2 0.0 3.0 3 0 0 3 3 2 0 AAA ATPase domain Baculo_PEP_C PF04513.7 AEO62817.1 - 0.12 12.2 6.8 0.66 9.7 4.7 2.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hemerythrin PF01814.18 AEO62817.1 - 0.53 10.4 11.6 1.1 9.3 7.3 2.1 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain APG6 PF04111.7 AEO62817.1 - 0.64 9.0 28.6 0.19 10.7 14.8 2.7 1 1 1 2 2 2 0 Autophagy protein Apg6 EMP24_GP25L PF01105.19 AEO62817.1 - 2.7 7.6 7.9 26 4.4 5.4 2.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD 2-Hacid_dh_C PF02826.14 AEO62818.1 - 1.1e-52 177.7 0.0 1.8e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AEO62818.1 - 5.5e-38 129.4 0.1 7.5e-38 129.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AEO62818.1 - 6.3e-06 26.1 0.2 1.8e-05 24.6 0.1 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 AEO62818.1 - 0.0013 18.2 0.2 0.0043 16.5 0.1 2.0 1 0 0 1 1 1 1 ACT domain AdoHcyase_NAD PF00670.16 AEO62818.1 - 0.0016 18.3 0.0 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 AEO62818.1 - 0.011 15.1 0.1 0.26 10.6 0.0 2.5 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Fucose_iso_N1 PF07881.7 AEO62818.1 - 0.053 13.0 0.0 0.88 9.0 0.0 2.2 2 0 0 2 2 2 0 L-fucose isomerase, first N-terminal domain 3HCDH_N PF02737.13 AEO62818.1 - 0.064 12.8 3.6 2.9 7.5 0.3 3.0 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAP PF00956.13 AEO62819.1 - 3.2e-82 275.3 5.8 3.2e-82 275.3 4.0 2.7 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) P5-ATPase PF12409.3 AEO62820.1 - 5.8e-36 122.9 0.3 2.3e-35 121.0 0.0 2.2 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 AEO62820.1 - 8.7e-28 96.9 0.0 1.7e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 AEO62820.1 - 2.1e-27 96.5 0.0 3.6e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AEO62820.1 - 1.1e-15 58.6 0.0 3.3e-14 53.8 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AEO62820.1 - 0.011 15.1 0.0 0.028 13.8 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 AEO62820.1 - 0.014 15.2 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AEO62820.1 - 0.052 13.1 0.0 1 8.9 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NADH_B2 PF14813.1 AEO62821.1 - 0.034 13.8 0.2 0.062 12.9 0.1 1.4 1 1 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase PF00069.20 AEO62822.1 - 4.8e-65 219.2 0.0 5.7e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO62822.1 - 1.1e-29 103.3 0.0 1.4e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO62822.1 - 0.0097 14.8 0.0 0.02 13.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Serglycin PF04360.7 AEO62824.1 - 0.19 11.4 0.3 0.29 10.8 0.2 1.2 1 0 0 1 1 1 0 Serglycin Metallophos PF00149.23 AEO62825.1 - 3.7e-38 130.9 0.0 5e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 AEO62825.1 - 4.9e-32 109.8 0.1 1.2e-31 108.5 0.1 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 AEO62825.1 - 5.2e-17 61.2 1.3 1.5e-10 40.5 0.2 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 AEO62825.1 - 8.4e-12 44.1 1.1 3.8e-06 26.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 AEO62825.1 - 2.4e-09 36.4 0.8 0.00054 19.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 AEO62825.1 - 2.6e-06 27.5 0.0 0.048 14.3 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO62825.1 - 2.7e-06 27.8 2.4 0.031 14.9 0.2 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 AEO62825.1 - 0.0022 17.8 0.5 0.067 13.0 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 AEO62825.1 - 0.013 15.5 0.6 20 5.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO62825.1 - 0.014 15.7 3.2 0.63 10.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 AEO62825.1 - 0.028 14.3 0.2 4.6 7.2 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 AEO62825.1 - 0.056 13.7 0.0 13 6.1 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat CTP_transf_3 PF02348.14 AEO62825.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase DUF4131 PF13567.1 AEO62826.1 - 0.0068 15.8 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) Sensor PF13796.1 AEO62826.1 - 0.075 12.6 1.0 0.1 12.2 0.7 1.2 1 0 0 1 1 1 0 Putative sensor DUF2417 PF10329.4 AEO62826.1 - 0.076 12.4 0.1 0.099 12.0 0.1 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) FH2 PF02181.18 AEO62827.1 - 2e-82 277.0 4.9 2e-82 277.0 3.4 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 AEO62827.1 - 3.5e-67 225.4 0.3 1.4e-66 223.4 0.0 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 AEO62827.1 - 5.1e-53 179.4 4.8 5.1e-53 179.4 3.3 3.2 3 1 1 4 4 4 1 Diaphanous FH3 Domain SlyX PF04102.7 AEO62827.1 - 0.0071 16.6 4.8 1.4 9.3 1.7 3.9 2 0 0 2 2 2 2 SlyX DUF2264 PF10022.4 AEO62828.1 - 2.4e-126 421.2 0.7 3e-126 420.9 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Surf_Ag_VNR PF07244.10 AEO62828.1 - 0.23 11.9 0.0 0.41 11.0 0.0 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat adh_short PF00106.20 AEO62829.1 - 8.9e-08 32.2 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO62829.1 - 4.9e-07 29.7 0.0 7.1e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF904 PF06005.7 AEO62829.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TRAPPC9-Trs120 PF08626.6 AEO62830.1 - 7.7e-140 467.3 0.0 3.3e-139 465.2 0.0 1.9 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Chorismate_bind PF00425.13 AEO62831.1 - 3.6e-65 219.8 0.0 1.7e-64 217.6 0.0 2.0 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 AEO62831.1 - 2.1e-20 72.9 0.0 3e-19 69.2 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 AEO62831.1 - 3.3e-12 46.6 0.0 7.9e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 AEO62831.1 - 8.5e-06 25.3 0.1 0.0054 16.2 0.0 2.3 2 0 0 2 2 2 2 Peptidase C26 Vps55 PF04133.9 AEO62832.1 - 1.1e-45 154.2 8.5 1.2e-45 154.1 5.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Proteasome PF00227.21 AEO62833.1 - 6.6e-51 172.3 0.0 8.5e-51 171.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AEO62833.1 - 3e-11 42.3 0.2 4.8e-11 41.7 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CLPTM1 PF05602.7 AEO62835.1 - 5.9e-156 519.5 0.0 7.3e-156 519.2 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Longin PF13774.1 AEO62837.1 - 4.6e-25 86.9 0.1 7.5e-25 86.3 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 AEO62837.1 - 2.8e-15 55.6 0.0 5.2e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 AEO62837.1 - 0.0048 16.6 0.3 0.012 15.3 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) DUF334 PF03904.8 AEO62837.1 - 0.054 12.8 1.0 6.6 5.9 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF334) DUF4404 PF14357.1 AEO62837.1 - 0.21 12.0 1.3 15 6.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ASXH PF13919.1 AEO62838.1 - 6.9e-19 68.0 0.5 9.6e-19 67.5 0.3 1.2 1 0 0 1 1 1 1 Asx homology domain Elong_Iki1 PF10483.4 AEO62839.1 - 3.7e-77 259.4 0.0 9.3e-77 258.1 0.0 1.6 1 1 0 1 1 1 1 Elongator subunit Iki1 NACHT PF05729.7 AEO62839.1 - 0.021 14.4 0.0 0.047 13.3 0.0 1.6 1 1 0 1 1 1 0 NACHT domain DUF1777 PF08648.7 AEO62840.1 - 5.8e-26 91.3 29.7 5.8e-26 91.3 20.6 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1777) SMAP PF15477.1 AEO62841.1 - 7.9e-18 64.5 4.8 7.9e-18 64.5 3.3 5.7 3 2 0 3 3 3 1 Small acidic protein family RAMP4 PF06624.7 AEO62842.1 - 2.8e-05 23.5 0.0 3.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 UPF0233 PF06781.7 AEO62842.1 - 0.12 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) Adeno_E3_14_5 PF04834.7 AEO62843.1 - 0.0047 17.3 0.1 0.0096 16.3 0.0 1.5 1 1 1 2 2 2 1 Early E3 14.5 kDa protein DUF3138 PF11336.3 AEO62843.1 - 0.032 12.4 2.5 0.038 12.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Mid1 PF12929.2 AEO62844.1 - 1.6e-135 452.1 8.0 1.9e-135 451.9 5.6 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 AEO62844.1 - 0.24 11.7 2.8 1.5 9.1 0.3 2.3 2 0 0 2 2 2 0 Fz domain TB2_DP1_HVA22 PF03134.14 AEO62845.1 - 2.9e-31 107.0 5.6 3.8e-31 106.6 3.9 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Far-17a_AIG1 PF04750.9 AEO62845.1 - 0.47 9.5 9.4 0.39 9.8 4.2 1.9 1 1 1 2 2 2 0 FAR-17a/AIG1-like protein Bestrophin PF01062.16 AEO62845.1 - 2.4 7.0 9.6 13 4.6 6.7 1.8 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel RFX_DNA_binding PF02257.10 AEO62846.1 - 3.8e-30 103.8 0.1 8.3e-30 102.7 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain Hydrolase_4 PF12146.3 AEO62847.1 - 5.6e-20 70.9 0.0 1.8e-19 69.3 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 AEO62847.1 - 1.7e-19 70.6 5.0 2e-19 70.3 3.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO62847.1 - 4.1e-16 59.0 0.1 5.9e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO62847.1 - 1.9e-05 24.3 0.1 2.4e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 AEO62847.1 - 0.0067 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S9 PF00326.16 AEO62847.1 - 0.0091 15.2 0.0 3 6.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 AEO62847.1 - 0.015 14.2 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 AEO62847.1 - 0.1 12.2 0.1 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) Cation_efflux PF01545.16 AEO62848.1 - 5.5e-29 101.1 4.4 6.7e-29 100.8 3.0 1.1 1 0 0 1 1 1 1 Cation efflux family Glyco_transf_8 PF01501.15 AEO62849.1 - 1.4e-26 93.3 0.2 2.3e-26 92.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 AEO62849.1 - 0.0052 16.1 0.0 0.0092 15.3 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Zip PF02535.17 AEO62849.1 - 2 7.3 6.5 3 6.7 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Chromo PF00385.19 AEO62850.1 - 1.1e-05 25.0 1.1 2.7e-05 23.7 0.8 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain IncA PF04156.9 AEO62850.1 - 0.00058 19.5 9.3 0.00058 19.5 6.5 3.5 2 1 1 3 3 3 1 IncA protein WEMBL PF05701.6 AEO62850.1 - 0.0058 15.1 39.2 0.011 14.2 27.1 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 AEO62850.1 - 0.96 7.0 43.5 3.9 5.0 16.9 2.2 1 1 1 2 2 2 0 Myosin tail Lectin_N PF03954.9 AEO62850.1 - 1.5 8.2 8.3 1.1 8.6 1.5 3.0 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain NPV_P10 PF05531.7 AEO62850.1 - 1.7 8.9 18.8 2.8 8.2 2.8 5.3 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.3 AEO62850.1 - 1.8 8.2 35.2 0.61 9.8 4.5 4.3 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 AEO62850.1 - 1.9 7.6 12.4 0.38 9.8 4.9 2.6 2 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF2422 PF10337.4 AEO62850.1 - 3.5 6.2 7.8 7.8 5.1 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Atg14 PF10186.4 AEO62850.1 - 5 5.9 37.5 2.1 7.2 8.4 3.2 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin PF00261.15 AEO62850.1 - 7.7 5.5 48.8 2.2 7.3 4.2 3.4 1 1 2 3 3 3 0 Tropomyosin COX5A PF02284.11 AEO62851.1 - 1.8e-42 143.6 0.3 2.4e-42 143.3 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ELO PF01151.13 AEO62852.1 - 3e-63 213.4 16.6 3.6e-63 213.1 11.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Spt20 PF12090.3 AEO62854.1 - 0.18 11.1 6.4 0.46 9.8 4.5 1.6 1 0 0 1 1 1 0 Spt20 family Serinc PF03348.10 AEO62854.1 - 0.8 8.3 3.1 1.2 7.7 2.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Suf PF05843.9 AEO62854.1 - 1.3 8.6 13.8 0.8 9.3 3.9 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) BAF1_ABF1 PF04684.8 AEO62854.1 - 5.3 5.7 15.7 7.9 5.1 10.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor F-box-like PF12937.2 AEO62855.1 - 3.6e-06 26.5 2.9 5.6e-06 25.9 1.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 AEO62855.1 - 0.031 13.9 0.2 0.51 10.0 0.0 2.9 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Glycogen_syn PF05693.8 AEO62856.1 - 0 1152.2 0.0 0 1151.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 AEO62856.1 - 9.2e-06 25.1 0.0 0.012 15.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 AEO62856.1 - 2.1e-05 24.1 0.2 3.7e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 AEO62856.1 - 4.6e-05 23.6 0.0 9.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Pkinase PF00069.20 AEO62858.1 - 7e-70 235.1 0.0 1e-69 234.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO62858.1 - 2.8e-34 118.3 0.0 6.4e-34 117.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO62858.1 - 0.0041 16.1 0.0 0.0066 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AEO62858.1 - 0.013 14.5 0.1 0.025 13.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acyl_transf_3 PF01757.17 AEO62859.1 - 5.1e-24 84.7 27.8 1.8e-23 82.9 19.3 2.0 1 1 0 1 1 1 1 Acyltransferase family Mucin PF01456.12 AEO62859.1 - 0.37 10.5 18.8 2.6 7.8 13.0 2.2 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF1624 PF07786.7 AEO62859.1 - 0.48 9.7 8.4 0.03 13.6 0.6 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1624) SSP160 PF06933.6 AEO62859.1 - 3.1 5.6 10.2 4.6 5.0 7.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pmp3 PF01679.12 AEO62861.1 - 1.9e-15 56.2 14.3 2.7e-15 55.7 9.9 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator zf-RanBP PF00641.13 AEO62862.1 - 2.9e-18 64.6 13.7 9.4e-11 40.6 1.3 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 AEO62862.1 - 1.1e-08 34.5 0.0 2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 AEO62862.1 - 3.5e-07 30.6 0.0 5.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 AEO62862.1 - 9.1e-06 25.5 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 AEO62862.1 - 0.12 12.2 6.5 0.3 10.9 0.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon WD40 PF00400.27 AEO62864.1 - 2.5e-36 122.2 2.5 1.7e-08 34.0 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 AEO62864.1 - 6.6e-31 106.0 0.2 2.3e-30 104.3 0.1 2.0 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex XRN_N PF03159.13 AEO62865.1 - 6.1e-41 140.3 0.1 7.3e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus SPC22 PF04573.7 AEO62866.1 - 4.9e-29 100.8 0.2 1.2e-18 67.0 0.0 2.5 3 0 0 3 3 3 2 Signal peptidase subunit Hid1 PF12722.2 AEO62867.1 - 1.5e-260 866.7 0.0 5.1e-260 864.9 0.0 1.7 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 AEO62867.1 - 4.2e-82 276.3 0.0 5.5e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein MEKHLA PF08670.6 AEO62867.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 MEKHLA domain NPCC PF08058.6 AEO62868.1 - 2.1e-30 105.4 0.2 1.6e-29 102.5 0.1 2.0 1 1 0 1 1 1 1 Nuclear pore complex component CytochromB561_N PF09786.4 AEO62868.1 - 0.0031 16.0 0.5 0.0033 15.9 0.3 1.2 1 0 0 1 1 1 1 Cytochrome B561, N terminal DUF2975 PF11188.3 AEO62868.1 - 0.022 14.4 0.2 0.035 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) AMP-binding PF00501.23 AEO62869.1 - 1.5e-15 56.5 0.1 2.5e-14 52.5 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme MCM PF00493.18 AEO62870.1 - 3.1e-143 476.5 0.2 4.2e-143 476.0 0.2 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AEO62870.1 - 1.2e-18 67.6 0.8 2.8e-18 66.5 0.2 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 AEO62870.1 - 6.7e-07 28.6 0.0 0.00022 20.4 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AEO62870.1 - 2e-05 24.3 0.0 4.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AEO62870.1 - 0.00027 20.5 0.1 0.0013 18.3 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 AEO62870.1 - 0.031 14.6 2.0 0.082 13.3 0.6 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 AEO62870.1 - 0.045 13.2 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 AEO62870.1 - 0.098 12.8 0.1 0.35 11.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Vps54 PF07928.7 AEO62871.1 - 5.1e-43 146.4 0.2 1.3e-42 145.1 0.1 1.8 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 AEO62871.1 - 7.2e-06 25.1 0.5 2.5e-05 23.3 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 AEO62871.1 - 0.00042 20.1 0.0 0.00088 19.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Sec8_exocyst PF04048.9 AEO62871.1 - 0.0068 16.0 0.5 0.32 10.6 0.1 2.7 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Sec15 PF04091.7 AEO62871.1 - 0.13 11.6 0.0 0.35 10.1 0.0 1.7 2 0 0 2 2 2 0 Exocyst complex subunit Sec15-like COG2 PF06148.6 AEO62871.1 - 4.5 7.1 5.9 2.6 7.9 0.6 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 APC8 PF04049.8 AEO62872.1 - 1.9e-49 167.0 0.1 9.7e-49 164.7 0.0 2.2 3 0 0 3 3 3 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 AEO62872.1 - 8.5e-19 66.3 11.6 0.00034 20.0 0.0 7.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.1 AEO62872.1 - 2.3e-17 62.3 16.8 2.9e-08 33.2 0.3 6.9 5 1 2 7 7 7 5 TPR repeat TPR_8 PF13181.1 AEO62872.1 - 1.7e-15 55.5 6.6 0.00026 20.5 0.0 7.4 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 AEO62872.1 - 1.5e-12 46.3 32.4 0.23 11.4 0.0 10.2 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 AEO62872.1 - 1.2e-09 37.9 17.5 0.025 15.2 0.0 9.1 6 2 4 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.1 AEO62872.1 - 2.4e-09 36.9 23.4 9.3e-05 22.2 0.4 6.7 5 1 3 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 AEO62872.1 - 8.3e-07 29.5 23.3 1.9e-05 25.1 0.3 7.2 6 2 2 8 8 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 AEO62872.1 - 3.2e-06 26.5 10.7 0.1 12.4 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 AEO62872.1 - 1.9e-05 24.7 11.1 0.58 10.3 0.0 5.8 3 1 4 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 AEO62872.1 - 2.5e-05 24.1 7.7 2.5 8.4 0.0 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 AEO62872.1 - 5.3e-05 22.9 13.9 0.021 14.6 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat DUF2424 PF10340.4 AEO62872.1 - 0.11 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) DUF3856 PF12968.2 AEO62872.1 - 0.17 11.7 3.3 1.5 8.6 0.1 3.3 2 1 0 3 3 2 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.1 AEO62872.1 - 0.3 11.6 25.2 0.54 10.8 0.3 9.2 10 1 0 10 10 10 0 Tetratricopeptide repeat MIT PF04212.13 AEO62872.1 - 0.31 10.9 3.7 0.52 10.2 0.0 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 AEO62872.1 - 0.74 10.2 18.1 15 5.9 0.1 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat polyprenyl_synt PF00348.12 AEO62873.1 - 4.6e-70 235.4 0.0 5.4e-70 235.1 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase RmlD_sub_bind PF04321.12 AEO62875.1 - 3.8e-55 186.8 0.0 4.9e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 AEO62875.1 - 7.2e-25 87.8 0.0 1.4e-23 83.5 0.0 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO62875.1 - 4.4e-12 45.4 0.2 1.5e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 AEO62875.1 - 6.3e-07 28.5 0.7 0.00014 20.8 0.0 3.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 AEO62875.1 - 9.9e-07 27.7 0.0 8.6e-06 24.6 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 AEO62875.1 - 2.4e-05 24.4 0.9 5.7e-05 23.2 0.6 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 AEO62875.1 - 0.0035 17.2 1.6 0.1 12.5 1.1 2.4 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 AEO62875.1 - 0.024 13.8 1.6 0.24 10.5 0.2 2.5 3 0 0 3 3 3 0 NmrA-like family KR PF08659.5 AEO62875.1 - 0.11 12.1 1.8 3.2 7.3 0.1 2.6 3 0 0 3 3 3 0 KR domain 6PF2K PF01591.13 AEO62876.1 - 8.7e-60 201.5 0.0 1.2e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 AEO62876.1 - 4e-22 79.0 0.2 6.5e-22 78.3 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 AEO62876.1 - 0.011 15.5 0.0 0.041 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 AEO62876.1 - 0.06 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Porin_3 PF01459.17 AEO62877.1 - 2.4e-82 276.3 1.3 2.7e-82 276.1 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin UCH_1 PF13423.1 AEO62878.1 - 3.5e-75 253.1 0.0 6.9e-75 252.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Acyl-CoA_dh_1 PF00441.19 AEO62879.1 - 1.4e-29 103.1 0.9 3e-29 102.0 0.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 AEO62879.1 - 4.9e-17 61.1 0.0 1.1e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 AEO62879.1 - 1.2e-15 57.9 3.9 6e-15 55.6 0.5 2.3 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 AEO62879.1 - 5.7e-13 49.4 0.0 1.1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Spo12 PF05032.7 AEO62880.1 - 1.4e-15 56.5 0.4 3.1e-15 55.5 0.2 1.6 1 0 0 1 1 1 1 Spo12 family TGS PF02824.16 AEO62881.1 - 1.5e-20 72.7 0.1 2.6e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 AEO62881.1 - 2e-19 69.6 0.1 5.9e-19 68.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO62881.1 - 1.1e-12 47.4 0.0 1.9e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AEO62881.1 - 1.5e-05 24.9 0.3 0.012 15.4 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 AEO62881.1 - 0.0021 18.5 0.0 0.0057 17.1 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 AEO62881.1 - 0.042 12.6 0.2 0.11 11.2 0.1 1.8 2 0 0 2 2 2 0 ArgK protein MCM PF00493.18 AEO62881.1 - 0.065 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family RRM_1 PF00076.17 AEO62882.1 - 1.5e-09 37.3 0.0 2.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO62882.1 - 1.9e-07 30.8 0.0 3.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO62882.1 - 2.3e-05 24.2 0.1 4.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO62882.1 - 0.00015 21.4 0.0 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 AEO62882.1 - 0.015 14.9 0.7 0.03 13.9 0.5 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cut12 PF11500.3 AEO62883.1 - 3.1e-41 140.5 14.7 3.1e-41 140.5 10.2 4.8 3 1 2 6 6 6 1 Spindle pole body formation-associated protein DUF4164 PF13747.1 AEO62883.1 - 0.004 17.2 10.6 0.004 17.2 7.3 5.3 6 1 0 6 6 6 1 Domain of unknown function (DUF4164) Retrotrans_gag PF03732.12 AEO62885.1 - 1.1e-06 28.5 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2 PF14223.1 AEO62885.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type TRP_2 PF08344.6 AEO62885.1 - 0.12 12.3 0.2 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Transient receptor ion channel II Prothymosin PF03247.9 AEO62887.1 - 0.037 14.1 9.2 0.048 13.8 6.4 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family CENP-B_dimeris PF09026.5 AEO62887.1 - 0.12 12.5 3.4 0.19 12.0 2.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DTHCT PF08070.6 AEO62887.1 - 0.22 12.2 5.5 0.18 12.5 3.0 1.4 1 1 0 1 1 1 0 DTHCT (NUC029) region Spore_coat_CotO PF14153.1 AEO62887.1 - 0.32 10.3 2.7 0.36 10.2 1.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Nucleoplasmin PF03066.10 AEO62887.1 - 0.48 9.9 5.7 0.54 9.7 4.0 1.1 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 AEO62887.1 - 0.93 9.0 7.0 0.97 9.0 4.8 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 AEO62887.1 - 1.1 9.6 8.8 1.6 9.0 6.1 1.5 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HGTP_anticodon2 PF12745.2 AEO62890.1 - 2.1e-82 276.3 0.1 2.1e-82 276.3 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 AEO62890.1 - 1.1e-77 260.7 0.0 8.5e-39 133.2 0.0 4.2 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 AEO62890.1 - 2.6e-49 167.6 0.0 2.4e-22 79.2 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 AEO62890.1 - 9.9e-15 54.3 1.5 2.7e-14 52.9 0.0 2.4 3 1 0 3 3 3 1 Histidyl-tRNA synthetase RWD PF05773.17 AEO62890.1 - 3.9e-12 46.0 0.0 1e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 RWD domain Kinase-like PF14531.1 AEO62890.1 - 2.5e-07 29.9 0.0 5.1e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 AEO62890.1 - 3.4e-05 23.6 2.0 0.17 11.5 0.0 3.4 3 0 0 3 3 3 2 Phosphotransferase enzyme family UQ_con PF00179.21 AEO62891.1 - 3e-34 117.4 0.0 4e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO62891.1 - 0.033 13.9 0.0 0.14 11.9 0.0 2.0 1 1 0 1 1 1 0 Prokaryotic E2 family B TFIIA PF03153.8 AEO62891.1 - 9 6.0 13.3 10 5.8 9.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Titin_Z PF09042.6 AEO62892.1 - 0.049 13.2 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 Titin Z DUF410 PF04190.8 AEO62893.1 - 1.5e-46 159.0 0.0 1.8e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DNA_pol_B PF00136.16 AEO62895.1 - 1e-146 489.4 3.5 1.4e-146 488.9 2.4 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 AEO62895.1 - 9e-78 261.3 0.0 1.8e-77 260.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 AEO62895.1 - 1.7e-21 75.9 3.4 4.7e-21 74.5 2.3 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 AEO62895.1 - 3.8e-05 23.3 0.0 8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 AEO62895.1 - 0.00019 21.2 0.2 0.0011 18.8 0.1 2.5 2 1 0 2 2 2 1 RNase_H superfamily DUF2614 PF11023.3 AEO62895.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) C1_1 PF00130.17 AEO62895.1 - 0.89 9.3 9.5 0.37 10.5 0.5 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GMC_oxred_N PF00732.14 AEO62896.1 - 2.5e-12 46.5 0.1 7.3e-10 38.4 0.0 2.4 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO62896.1 - 2.9e-10 40.6 0.2 3.2e-09 37.2 0.0 2.6 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 AEO62896.1 - 0.00078 18.4 0.4 0.0014 17.5 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO62896.1 - 0.00087 18.2 1.9 0.14 11.0 0.3 3.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO62896.1 - 0.0064 16.4 0.3 0.23 11.4 0.1 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 AEO62896.1 - 0.0066 15.5 0.6 0.013 14.6 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 AEO62896.1 - 0.042 12.7 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 AEO62896.1 - 0.13 12.1 0.2 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AEO62896.1 - 0.18 10.5 0.4 0.28 10.0 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ELFV_dehydrog PF00208.16 AEO62897.1 - 4.7e-79 265.4 1.1 5.8e-79 265.1 0.8 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 AEO62897.1 - 1.7e-48 163.5 0.0 1.5e-47 160.4 0.0 2.2 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain AlaDh_PNT_C PF01262.16 AEO62897.1 - 0.033 13.7 0.2 0.062 12.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 AEO62897.1 - 0.14 12.3 0.1 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Ferritin_2 PF13668.1 AEO62898.1 - 5.1e-40 136.5 2.5 5.1e-40 136.5 1.7 1.5 2 0 0 2 2 2 1 Ferritin-like domain GARS_C PF02843.11 AEO62898.1 - 6.3 7.0 6.6 0.54 10.4 0.1 2.5 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain Sirohm_synth_M PF14824.1 AEO62899.1 - 0.13 11.2 0.0 0.32 10.0 0.0 1.7 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central RNB PF00773.14 AEO62900.1 - 8.8e-77 258.5 0.1 4.7e-76 256.1 0.0 2.2 3 0 0 3 3 3 1 RNB domain DUF4239 PF14023.1 AEO62900.1 - 0.03 13.6 0.2 0.08 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF3275 PF11679.3 AEO62900.1 - 0.43 10.1 6.8 2.2 7.8 4.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3275) GLE1 PF07817.8 AEO62901.1 - 1.1e-24 86.7 0.0 8.7e-24 83.8 0.0 2.0 1 1 0 1 1 1 1 GLE1-like protein CAF-1_p150 PF11600.3 AEO62901.1 - 1 8.6 13.5 0.33 10.3 6.7 1.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Syntaxin-6_N PF09177.6 AEO62902.1 - 3e-26 91.6 0.4 1.8e-25 89.1 0.0 2.0 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 AEO62902.1 - 2.4e-14 52.7 6.7 3.8e-14 52.1 2.6 2.6 3 0 0 3 3 3 1 SNARE domain DUF3802 PF12290.3 AEO62902.1 - 0.27 11.5 1.7 4.2 7.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3802) AATF-Che1 PF13339.1 AEO62902.1 - 0.39 10.8 2.7 0.25 11.5 0.6 1.6 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF1470 PF07336.6 AEO62902.1 - 0.95 9.8 5.7 1.2 9.4 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1470) PilJ PF13675.1 AEO62902.1 - 1.1 9.5 6.5 0.6 10.4 1.8 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4164 PF13747.1 AEO62902.1 - 4 7.6 6.5 1.8 8.7 0.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Pro_isomerase PF00160.16 AEO62903.1 - 1e-47 162.2 0.5 1.2e-47 162.0 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Trm112p PF03966.11 AEO62904.1 - 5e-17 62.0 0.1 6.2e-17 61.7 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.1 AEO62904.1 - 0.046 13.9 0.2 0.09 13.0 0.1 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-NADH-PPase PF09297.6 AEO62904.1 - 0.057 12.9 0.1 0.095 12.2 0.1 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain RRN7 PF11781.3 AEO62904.1 - 0.16 11.4 1.0 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 ATP-synt_S1 PF05827.7 AEO62905.1 - 8.3e-39 133.5 0.0 1.2e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) ketoacyl-synt PF00109.21 AEO62906.1 - 3.4e-59 200.4 0.3 8e-59 199.1 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 AEO62906.1 - 8.3e-55 185.2 1.1 8.3e-55 185.2 0.7 3.2 4 0 0 4 4 3 1 KR domain PS-DH PF14765.1 AEO62906.1 - 1.7e-48 165.2 0.6 3.6e-48 164.2 0.4 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 AEO62906.1 - 3.4e-44 151.4 0.0 6.6e-44 150.5 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 AEO62906.1 - 6.2e-40 136.8 0.8 6.2e-40 136.8 0.5 4.4 6 0 0 6 6 6 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 AEO62906.1 - 1.7e-35 121.4 0.6 1.7e-35 121.4 0.4 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 AEO62906.1 - 2.5e-19 69.1 0.2 3.1e-18 65.5 0.0 2.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO62906.1 - 2.6e-12 47.7 0.0 2e-11 44.8 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO62906.1 - 3.5e-09 36.3 2.8 9e-09 35.0 1.9 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 AEO62906.1 - 2.2e-07 31.0 0.0 5.6e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.5 AEO62906.1 - 0.0028 17.2 0.3 0.29 10.8 0.1 2.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Endonuclease_1 PF04231.8 AEO62906.1 - 0.52 10.0 0.0 1.1 9.0 0.0 1.4 1 0 0 1 1 1 0 Endonuclease I Abhydrolase_6 PF12697.2 AEO62907.1 - 2.7e-21 76.5 0.1 3.5e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO62907.1 - 5.6e-19 68.3 0.0 1.4e-18 67.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO62907.1 - 5.8e-11 42.0 0.0 1.6e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.7 AEO62907.1 - 1.5e-08 33.5 0.0 3.7e-05 22.3 0.0 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 AEO62907.1 - 1.1e-07 31.6 0.0 2.7e-07 30.3 0.0 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 AEO62907.1 - 5.5e-06 26.1 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF1100 PF06500.6 AEO62907.1 - 0.0058 15.2 0.0 0.0078 14.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) PHB_depo_C PF06850.6 AEO62907.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 PHB de-polymerase C-terminus DLH PF01738.13 AEO62907.1 - 0.026 13.7 0.0 0.054 12.7 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 AEO62907.1 - 0.028 13.9 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Bac_thur_toxin PF01338.13 AEO62908.1 - 0.14 11.3 0.6 1.8 7.7 0.1 2.1 1 1 1 2 2 2 0 Bacillus thuringiensis toxin adh_short PF00106.20 AEO62909.1 - 1.8e-20 73.4 0.1 2.5e-20 73.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO62909.1 - 2.4e-15 56.9 0.0 2.9e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO62909.1 - 0.00014 21.5 1.0 0.00016 21.4 0.1 1.6 2 0 0 2 2 2 1 KR domain NmrA PF05368.8 AEO62909.1 - 0.00095 18.4 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 AEO62909.1 - 0.00099 18.5 0.0 0.0013 18.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO62909.1 - 0.0026 17.7 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 AEO62909.1 - 0.0093 15.1 0.0 0.13 11.3 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 AEO62909.1 - 0.013 14.4 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain PAE PF03283.8 AEO62909.1 - 0.024 13.2 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase FAD_binding_4 PF01565.18 AEO62910.1 - 8.4e-20 70.6 0.9 2.1e-19 69.4 0.7 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO62910.1 - 1.4e-11 44.1 1.5 3e-11 43.0 0.2 2.3 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 AEO62910.1 - 0.12 11.4 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding p450 PF00067.17 AEO62911.1 - 5.5e-53 180.1 0.0 6.3e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 AEO62913.1 - 1.6e-25 89.2 2.4 3.1e-25 88.2 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO62913.1 - 0.00047 19.9 0.1 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Tropomyosin_1 PF12718.2 AEO62914.1 - 5e-50 169.0 35.8 6e-50 168.8 24.8 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 AEO62914.1 - 8e-09 34.9 35.7 0.0001 21.4 8.8 3.0 1 1 2 3 3 3 3 Tropomyosin CENP-F_leu_zip PF10473.4 AEO62914.1 - 3.2e-05 23.8 35.7 0.0021 17.9 3.3 2.6 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cast PF10174.4 AEO62914.1 - 0.00094 17.3 30.3 0.001 17.2 21.0 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Spc7 PF08317.6 AEO62914.1 - 0.0051 15.5 28.9 0.0086 14.7 10.0 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein APG6 PF04111.7 AEO62914.1 - 0.0056 15.7 36.2 0.054 12.5 14.1 2.1 1 1 1 2 2 2 2 Autophagy protein Apg6 ATG16 PF08614.6 AEO62914.1 - 0.006 16.4 29.6 0.28 11.0 7.1 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.14 AEO62914.1 - 0.0075 14.0 34.4 0.0089 13.8 23.9 1.0 1 0 0 1 1 1 1 Myosin tail Mod_r PF07200.8 AEO62914.1 - 0.0093 15.8 27.7 0.3 10.9 2.1 2.1 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein NPV_P10 PF05531.7 AEO62914.1 - 0.012 15.7 9.5 0.83 9.9 0.1 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ERM PF00769.14 AEO62914.1 - 0.013 15.1 39.4 0.033 13.7 10.8 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.3 AEO62914.1 - 0.015 15.1 36.5 0.02 14.6 12.3 3.2 1 1 1 2 2 1 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 AEO62914.1 - 0.044 13.6 32.5 0.28 11.0 8.5 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.7 AEO62914.1 - 0.052 13.3 19.8 0.058 13.1 2.3 2.3 1 1 1 2 2 2 0 Laminin Domain II AAA_13 PF13166.1 AEO62914.1 - 0.07 11.5 23.2 0.09 11.2 16.1 1.2 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 AEO62914.1 - 0.086 12.0 33.4 0.25 10.5 11.3 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding LPP PF04728.8 AEO62914.1 - 0.13 12.1 0.6 1.6 8.5 0.0 2.8 2 2 1 3 3 3 0 Lipoprotein leucine-zipper TMF_TATA_bd PF12325.3 AEO62914.1 - 0.13 12.0 29.6 1.8 8.3 14.9 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding NABP PF07990.7 AEO62914.1 - 0.15 11.2 5.3 0.17 11.1 3.7 1.2 1 0 0 1 1 1 0 Nucleic acid binding protein NABP DUF4200 PF13863.1 AEO62914.1 - 0.18 11.7 37.5 1.1 9.2 10.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3166 PF11365.3 AEO62914.1 - 0.2 12.1 20.2 0.59 10.6 6.7 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF3166) PilJ PF13675.1 AEO62914.1 - 0.21 11.8 14.0 0.77 10.0 3.4 2.8 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term KLRAQ PF10205.4 AEO62914.1 - 0.23 11.5 21.2 0.053 13.5 6.5 2.7 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein bZIP_1 PF00170.16 AEO62914.1 - 0.24 11.3 33.0 1.2 9.1 3.4 5.0 1 1 4 5 5 5 0 bZIP transcription factor Syntaxin-6_N PF09177.6 AEO62914.1 - 0.26 11.7 19.4 0.79 10.1 1.8 3.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal IFT46_B_C PF12317.3 AEO62914.1 - 0.26 10.6 9.2 0.059 12.7 3.4 1.8 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal BRE1 PF08647.6 AEO62914.1 - 0.37 10.8 30.1 0.33 10.9 3.4 2.4 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Reo_sigmaC PF04582.7 AEO62914.1 - 0.46 9.6 2.7 9.2 5.3 0.0 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TBPIP PF07106.8 AEO62914.1 - 0.47 9.9 28.1 1.6 8.2 7.5 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Herpes_U30 PF04523.8 AEO62914.1 - 0.54 7.6 8.6 0.65 7.3 6.0 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 Atg14 PF10186.4 AEO62914.1 - 0.55 9.1 26.6 0.33 9.8 8.0 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Lebercilin PF15619.1 AEO62914.1 - 0.56 9.6 33.1 0.85 9.0 11.1 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Nsp1_C PF05064.8 AEO62914.1 - 0.58 9.8 22.4 0.054 13.1 5.6 2.6 1 1 1 2 2 2 0 Nsp1-like C-terminal region Spectrin PF00435.16 AEO62914.1 - 0.59 10.4 29.6 8.3 6.7 6.4 3.1 1 1 1 2 2 2 0 Spectrin repeat Herpes_capsid PF06112.6 AEO62914.1 - 0.62 10.0 3.8 0.41 10.6 0.3 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Cortex-I_coil PF09304.5 AEO62914.1 - 0.66 10.0 29.4 1.4 9.0 0.2 3.6 1 1 2 3 3 3 0 Cortexillin I, coiled coil BLOC1_2 PF10046.4 AEO62914.1 - 0.71 10.0 22.7 5 7.3 5.8 3.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 AEO62914.1 - 0.73 9.3 34.9 5.1 6.6 10.7 2.1 1 1 1 2 2 2 0 IncA protein Vps5 PF09325.5 AEO62914.1 - 0.81 8.9 24.2 0.016 14.4 5.9 2.5 2 1 0 2 2 2 0 Vps5 C terminal like HAP1_N PF04849.8 AEO62914.1 - 0.9 8.4 30.2 3.1 6.6 20.9 2.6 1 1 0 1 1 1 0 HAP1 N-terminal conserved region TPR_MLP1_2 PF07926.7 AEO62914.1 - 0.93 9.2 36.7 0.5 10.1 11.1 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein EzrA PF06160.7 AEO62914.1 - 0.97 7.5 26.1 0.17 10.0 3.8 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Striatin PF08232.7 AEO62914.1 - 0.98 9.7 26.6 0.72 10.1 11.3 2.3 1 1 1 2 2 2 0 Striatin family CCDC155 PF14662.1 AEO62914.1 - 1 8.9 36.0 3.3 7.2 11.9 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF4201 PF13870.1 AEO62914.1 - 1.1 8.7 26.8 46 3.3 18.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Caprin-1_C PF12287.3 AEO62914.1 - 1.3 8.3 3.9 1.2 8.4 1.5 1.9 1 1 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term CDC37_N PF03234.9 AEO62914.1 - 1.7 8.9 23.7 9.7 6.4 16.4 2.1 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding FlaC_arch PF05377.6 AEO62914.1 - 1.9 8.4 19.2 4.6 7.2 0.1 4.2 3 3 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.3 AEO62914.1 - 1.9 7.6 28.5 3.8 6.7 9.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.4 AEO62914.1 - 2.1 8.3 27.4 0.97 9.4 7.5 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.7 AEO62914.1 - 2.3 8.0 15.1 2.7 7.8 1.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) rRNA_proc-arch PF13234.1 AEO62914.1 - 2.8 7.0 16.1 0.13 11.3 2.0 2.3 1 1 0 2 2 2 0 rRNA-processing arch domain DUF3584 PF12128.3 AEO62914.1 - 2.9 5.0 29.6 3.9 4.6 20.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Seryl_tRNA_N PF02403.17 AEO62914.1 - 3 7.9 31.3 6 6.9 4.1 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FUSC PF04632.7 AEO62914.1 - 4.2 5.6 8.1 4.9 5.4 5.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fmp27_WPPW PF10359.4 AEO62914.1 - 4.3 5.6 24.0 0.048 12.0 5.1 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF972 PF06156.8 AEO62914.1 - 4.4 7.7 27.7 20 5.5 0.7 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF3287 PF11690.3 AEO62914.1 - 5.6 7.0 12.2 0.34 10.9 0.8 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) Rootletin PF15035.1 AEO62914.1 - 6.1 6.7 30.4 60 3.5 21.1 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Fib_alpha PF08702.5 AEO62914.1 - 6.6 6.8 18.8 0.58 10.2 2.8 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4140 PF13600.1 AEO62914.1 - 6.8 7.1 27.4 1 9.8 2.7 3.7 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Phage_DsbA PF11126.3 AEO62914.1 - 7.1 6.7 15.3 0.22 11.6 1.0 3.4 2 1 1 3 3 3 0 Transcriptional regulator DsbA Shugoshin_N PF07558.6 AEO62914.1 - 7.2 6.4 12.7 0.45 10.2 0.4 3.9 4 1 1 5 5 3 0 Shugoshin N-terminal coiled-coil region Mnd1 PF03962.10 AEO62914.1 - 7.3 6.2 32.6 7.5 6.1 8.9 2.2 1 1 1 2 2 2 0 Mnd1 family Uds1 PF15456.1 AEO62914.1 - 9.4 6.2 27.2 24 4.9 4.8 2.8 1 1 2 3 3 3 0 Up-regulated During Septation DUF2718 PF10918.3 AEO62915.1 - 0.037 14.0 0.4 0.068 13.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) N-SET PF11764.3 AEO62916.1 - 6.7e-45 152.9 0.2 6.7e-45 152.9 0.1 3.3 4 1 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 AEO62916.1 - 1.6e-25 88.2 0.3 4.1e-25 86.8 0.2 1.8 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 AEO62916.1 - 9.1e-25 87.8 0.2 9.1e-25 87.8 0.1 3.6 3 2 0 3 3 3 1 SET domain ATP-synt_ab PF00006.20 AEO62917.1 - 3.2e-112 373.2 0.0 4.3e-112 372.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AEO62917.1 - 4.1e-18 65.9 1.0 7.1e-18 65.1 0.7 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AEO62917.1 - 4.3e-14 52.4 5.2 6.6e-14 51.8 2.9 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain LcrG PF07216.7 AEO62917.1 - 0.07 13.1 0.6 0.24 11.4 0.3 1.9 2 0 0 2 2 2 0 LcrG protein AAA_14 PF13173.1 AEO62917.1 - 0.16 11.9 0.0 0.38 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF4048 PF13257.1 AEO62918.1 - 4.9e-17 62.4 17.8 2.4e-15 56.8 4.6 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF4048) BRCT PF00533.21 AEO62919.1 - 0.00049 20.1 0.0 0.0014 18.6 0.0 1.9 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ras PF00071.17 AEO62920.1 - 1.1e-31 109.4 0.3 1.4e-31 109.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO62920.1 - 3.9e-21 75.7 0.1 3.2e-20 72.8 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AEO62920.1 - 4.1e-07 29.4 0.1 5.8e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AEO62920.1 - 2.1e-05 23.7 0.2 2.8e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.6 AEO62920.1 - 0.0099 14.5 0.2 0.29 9.7 0.0 2.0 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.18 AEO62920.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 AEO62920.1 - 0.075 11.7 0.5 0.2 10.3 0.0 1.8 1 1 1 2 2 2 0 G-protein alpha subunit GCV_H PF01597.14 AEO62921.1 - 2.1e-34 117.8 0.7 2.6e-34 117.5 0.5 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein PdxJ PF03740.8 AEO62921.1 - 0.1 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ Porphobil_deam PF01379.15 AEO62922.1 - 8.2e-77 256.9 0.0 1.1e-76 256.5 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 AEO62922.1 - 1.3e-19 70.0 1.1 2.5e-19 69.1 0.8 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DUF1510 PF07423.6 AEO62923.1 - 0.063 12.6 6.4 0.08 12.2 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Paf1 PF03985.8 AEO62923.1 - 0.64 8.6 6.6 0.77 8.4 4.6 1.0 1 0 0 1 1 1 0 Paf1 TIP120 PF08623.5 AEO62924.1 - 7.4e-67 224.1 1.9 5.2e-64 214.8 0.0 4.5 3 1 2 5 5 5 2 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 AEO62924.1 - 8.4e-19 67.6 24.0 0.0008 19.6 0.1 9.6 7 3 2 9 9 9 4 HEAT repeats HEAT PF02985.17 AEO62924.1 - 6.5e-13 47.5 21.5 0.12 12.4 0.0 10.9 12 0 0 12 12 12 3 HEAT repeat Cnd1 PF12717.2 AEO62924.1 - 4.9e-05 23.2 6.4 2.2 8.0 0.0 5.8 5 1 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 AEO62924.1 - 6.8e-05 23.1 1.8 0.25 11.7 0.0 6.5 6 3 2 8 8 8 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 AEO62924.1 - 0.00029 21.2 31.1 1.7 9.2 0.8 12.1 11 2 4 15 15 15 2 HEAT-like repeat Cnd3 PF12719.2 AEO62924.1 - 0.0022 17.0 0.1 0.073 12.0 0.0 3.0 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain DUF2457 PF10446.4 AEO62924.1 - 0.66 8.6 5.7 1.1 7.8 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Prenyltrans PF00432.16 AEO62925.1 - 8.8e-29 98.7 6.8 2.2e-09 36.7 0.2 5.8 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 AEO62925.1 - 6.3e-25 87.2 0.0 6.4e-11 42.2 0.1 6.3 4 2 2 6 6 6 5 Prenyltransferase-like Prenyltrans_2 PF13249.1 AEO62925.1 - 1.9e-24 86.2 3.2 9.9e-15 54.9 0.1 5.1 4 2 1 5 5 5 4 Prenyltransferase-like Pec_lyase PF09492.5 AEO62925.1 - 1.4e-07 31.0 0.5 0.16 11.1 0.0 4.9 3 2 2 5 5 5 3 Pectic acid lyase A2M_comp PF07678.9 AEO62925.1 - 6.5e-05 22.2 0.0 0.019 14.1 0.0 3.4 3 1 2 5 5 5 2 A-macroglobulin complement component Chromadorea_ALT PF05535.7 AEO62925.1 - 0.041 13.9 0.7 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 Chromadorea ALT protein TP6A_N PF04406.9 AEO62926.1 - 1.6e-19 69.3 0.0 3.5e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Ank_2 PF12796.2 AEO62927.1 - 1.5e-21 76.5 0.1 1.2e-13 51.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AEO62927.1 - 3.3e-16 58.1 0.6 1.7e-06 27.5 0.2 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 AEO62927.1 - 1.1e-13 51.2 0.2 4.9e-05 23.7 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO62927.1 - 1.3e-13 49.7 0.0 0.00011 22.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 AEO62927.1 - 1.6e-13 50.3 0.5 7.1e-07 29.2 0.4 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ketoacyl-synt_2 PF13723.1 AEO62927.1 - 0.0016 17.7 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain bZIP_1 PF00170.16 AEO62928.1 - 0.0081 16.0 1.3 0.0081 16.0 0.9 2.2 2 0 0 2 2 2 1 bZIP transcription factor HAP1_N PF04849.8 AEO62928.1 - 0.1 11.5 0.8 0.18 10.7 0.6 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region HALZ PF02183.13 AEO62928.1 - 0.11 12.2 2.0 0.27 10.9 1.4 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Pkinase PF00069.20 AEO62929.1 - 4.4e-06 26.0 0.0 0.0015 17.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.18 AEO62929.1 - 0.061 13.0 0.1 0.061 13.0 0.1 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF3422 PF11902.3 AEO62929.1 - 0.083 11.7 0.3 0.13 11.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) Lipase_GDSL_2 PF13472.1 AEO62930.1 - 3.2e-17 63.2 1.6 5.8e-17 62.3 1.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO62930.1 - 4.2e-13 49.6 0.8 1.2e-12 48.1 0.5 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase p450 PF00067.17 AEO62931.1 - 4.6e-52 177.0 0.0 2.7e-41 141.5 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 PLDc_2 PF13091.1 AEO62933.1 - 1.7e-13 50.3 0.0 1.2e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 AEO62933.1 - 3.7e-08 32.8 1.7 0.013 15.3 0.2 3.2 2 1 0 2 2 2 2 Phospholipase D Active site motif NDUFA12 PF05071.11 AEO62934.1 - 3.1e-26 91.8 1.6 4.3e-26 91.4 1.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PNTB PF02233.11 AEO62935.1 - 4.6e-172 572.9 25.1 4.6e-172 572.9 17.4 1.7 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 AEO62935.1 - 3.7e-53 179.5 0.7 6.8e-53 178.6 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 AEO62935.1 - 1.3e-48 164.4 1.8 1.5e-48 164.2 0.2 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 AEO62935.1 - 1.3e-31 108.5 3.4 1.3e-31 108.5 2.4 5.5 5 2 2 7 7 7 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 AEO62935.1 - 0.0018 17.4 0.2 2.3 7.3 0.0 3.0 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 AEO62935.1 - 0.018 14.9 0.5 0.076 12.8 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 AEO62935.1 - 0.021 15.4 0.0 0.064 13.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 AEO62935.1 - 0.022 14.3 0.0 0.098 12.2 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain NAD_binding_8 PF13450.1 AEO62935.1 - 0.068 13.2 2.8 0.59 10.1 1.9 2.8 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_18 PF00704.23 AEO62937.1 - 4.4e-46 157.9 1.0 7.1e-46 157.2 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 AEO62937.1 - 5.9e-10 38.8 0.0 0.00046 20.0 0.0 2.6 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 AEO62937.1 - 0.0046 16.9 9.3 0.0046 16.9 6.5 3.3 2 1 0 2 2 2 1 Chitin recognition protein ADH_N PF08240.7 AEO62938.1 - 0.055 13.2 0.5 0.29 10.9 0.1 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain Cellulase PF00150.13 AEO62940.1 - 7.5e-48 163.1 0.1 9.4e-48 162.8 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) IstB_IS21_ATP PF08483.6 AEO62943.1 - 0.012 15.3 0.2 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding N-terminal MFS_1 PF07690.11 AEO62944.1 - 2.1e-28 99.0 61.1 1.9e-27 95.9 38.5 3.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Myc_target_1 PF15179.1 AEO62944.1 - 0.012 15.2 0.8 0.022 14.3 0.5 1.3 1 0 0 1 1 1 0 Myc target protein 1 Sdh_cyt PF01127.17 AEO62948.1 - 6.9e-20 71.0 2.8 9.1e-20 70.7 1.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1546 PF07571.8 AEO62949.1 - 6e-30 103.2 0.0 1.6e-29 101.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 AEO62949.1 - 1.4e-17 63.4 0.0 3.1e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 AEO62949.1 - 0.00043 20.3 0.1 0.00082 19.4 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 zf-C2H2_4 PF13894.1 AEO62950.1 - 0.099 13.0 0.6 0.099 13.0 0.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO62950.1 - 1.6 9.2 4.6 0.59 10.5 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type MFS_1 PF07690.11 AEO62951.1 - 2e-28 99.1 24.8 2e-28 99.1 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO62951.1 - 5.5e-25 87.8 23.8 7.1e-23 80.8 16.5 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2306 PF10067.4 AEO62951.1 - 2.1 8.5 7.2 1.8 8.7 0.4 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2306) Pro-kuma_activ PF09286.6 AEO62952.1 - 7.9e-37 126.4 0.0 2e-36 125.1 0.0 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 AEO62952.1 - 4.7e-06 25.9 0.0 9.2e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Subtilase family DEAD PF00270.24 AEO62953.1 - 4.7e-41 140.1 0.4 1.2e-40 138.7 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO62953.1 - 4.1e-29 100.2 0.2 9.1e-29 99.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 AEO62953.1 - 0.0029 17.3 0.3 0.0067 16.1 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 AEO62953.1 - 0.0065 16.3 0.1 0.019 14.8 0.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 AEO62953.1 - 0.0093 15.2 0.5 0.016 14.4 0.1 1.5 2 0 0 2 2 2 1 SecA DEAD-like domain AAA_30 PF13604.1 AEO62953.1 - 0.015 14.8 0.7 0.035 13.6 0.5 1.6 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 AEO62953.1 - 0.036 13.8 0.3 0.12 12.1 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.9 AEO62953.1 - 0.051 13.2 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.1 AEO62953.1 - 0.053 13.6 0.5 0.23 11.5 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 AEO62953.1 - 0.11 12.0 0.2 0.14 11.7 0.2 1.5 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.3 AEO62954.1 - 1.1e-68 230.6 3.2 1.4e-68 230.3 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 AEO62954.1 - 5.5e-13 48.1 0.8 5.9e-12 44.9 0.0 2.5 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 AEO62954.1 - 6.5e-11 42.0 2.1 3e-08 33.5 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO62954.1 - 1.2e-10 41.1 1.1 2.1e-08 34.0 0.4 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 AEO62954.1 - 5e-05 23.3 0.2 0.082 13.0 0.0 3.7 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 AEO62954.1 - 0.014 15.0 0.2 0.014 15.0 0.1 2.6 3 1 0 3 3 3 0 DBF zinc finger SpoOE-like PF09388.5 AEO62954.1 - 0.016 14.7 0.6 0.031 13.7 0.4 1.5 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein zf-C2H2_4 PF13894.1 AEO62954.1 - 0.13 12.6 4.0 5.6 7.5 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger C1_2 PF03107.11 AEO62954.1 - 1.8 8.7 3.9 2.9 8.0 0.6 2.6 2 0 0 2 2 2 0 C1 domain GIY-YIG PF01541.19 AEO62955.1 - 4.6e-07 30.1 0.0 9.4e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-RING_2 PF13639.1 AEO62955.1 - 0.0027 17.5 2.7 0.0044 16.8 1.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H_2 PF13832.1 AEO62955.1 - 0.0067 16.4 0.4 0.011 15.6 0.3 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain T5orf172 PF10544.4 AEO62955.1 - 0.025 14.9 0.0 0.062 13.6 0.0 1.8 2 0 0 2 2 2 0 T5orf172 domain FANCL_C PF11793.3 AEO62955.1 - 0.03 14.2 1.5 0.051 13.5 1.0 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C2HC PF01530.13 AEO62955.1 - 0.053 13.2 0.7 0.11 12.1 0.5 1.6 1 0 0 1 1 1 0 Zinc finger, C2HC type zf-HC5HC2H PF13771.1 AEO62955.1 - 0.064 13.3 1.3 0.12 12.5 0.9 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 AEO62955.1 - 0.14 11.9 4.6 0.27 11.0 0.8 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 AEO62955.1 - 0.15 11.7 3.7 0.28 10.9 2.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.1 AEO62955.1 - 0.32 11.0 3.0 0.63 10.1 2.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YdjO PF14169.1 AEO62955.1 - 0.69 9.4 5.9 1.1 8.6 0.0 2.7 3 0 0 3 3 3 0 Cold-inducible protein YdjO zf-RING-like PF08746.6 AEO62955.1 - 1.2 9.2 7.0 5 7.1 4.8 2.0 1 1 0 1 1 1 0 RING-like domain PLU-1 PF08429.6 AEO62956.1 - 5.6e-104 347.6 16.4 7.6e-101 337.3 10.8 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 AEO62956.1 - 1.3e-42 144.6 0.1 3.4e-42 143.2 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 AEO62956.1 - 6.8e-27 93.1 0.0 1.9e-26 91.7 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 AEO62956.1 - 3.4e-17 61.8 30.6 1.2e-09 37.7 3.9 4.0 4 0 0 4 4 4 2 PHD-finger JmjN PF02375.12 AEO62956.1 - 2e-14 52.8 1.4 4.2e-14 51.7 1.0 1.6 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 AEO62956.1 - 2.4e-14 53.1 5.2 7.4e-14 51.5 3.6 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger Prok-RING_1 PF14446.1 AEO62956.1 - 0.0051 16.5 1.3 0.0051 16.5 0.9 3.4 2 1 1 3 3 3 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 AEO62956.1 - 0.78 9.5 16.2 0.72 9.6 0.2 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 AEO62956.1 - 1 8.7 12.4 0.046 13.0 1.2 2.8 2 0 0 2 2 2 0 PHD-finger Rubredoxin PF00301.15 AEO62956.1 - 1.2 9.0 16.2 0.014 15.2 1.7 3.2 2 1 1 3 3 3 0 Rubredoxin DUF1688 PF07958.6 AEO62957.1 - 3.1e-176 586.0 0.0 3.6e-176 585.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Bys1 PF04681.7 AEO62959.1 - 8.4e-15 54.8 0.1 1e-14 54.5 0.1 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein NOB1_Zn_bind PF08772.6 AEO62960.1 - 1.4e-32 111.3 3.9 2.9e-32 110.3 2.7 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 AEO62960.1 - 1.7e-05 24.6 2.2 4.5e-05 23.2 1.5 1.7 1 0 0 1 1 1 1 Drug resistance and apoptosis regulator FAM75 PF14650.1 AEO62960.1 - 0.54 9.5 4.4 0.47 9.7 1.6 1.8 2 0 0 2 2 2 0 FAM75 family zf-NADH-PPase PF09297.6 AEO62960.1 - 1.7 8.2 6.1 0.24 10.9 0.5 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Pex14_N PF04695.8 AEO62960.1 - 3.8 7.5 10.3 6.9 6.7 3.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nop10p PF04135.7 AEO62961.1 - 1e-17 63.5 0.1 1.1e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Alpha_GJ PF03229.8 AEO62962.1 - 1.3 9.3 13.3 0.14 12.5 5.4 2.0 2 0 0 2 2 2 0 Alphavirus glycoprotein J zf-C2H2_4 PF13894.1 AEO62964.1 - 2.5e-06 27.4 8.6 2.9e-05 24.0 1.7 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO62964.1 - 2.3e-05 24.4 1.2 2.3e-05 24.4 0.8 3.3 3 1 0 3 3 3 1 Zinc finger, C2H2 type UPF0515 PF15135.1 AEO62964.1 - 0.0037 16.3 1.3 0.0044 16.1 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 zf-C2H2_6 PF13912.1 AEO62964.1 - 0.01 15.6 0.6 0.01 15.6 0.4 2.2 3 0 0 3 3 1 0 C2H2-type zinc finger zf-Di19 PF05605.7 AEO62964.1 - 0.018 15.1 0.1 0.018 15.1 0.1 2.4 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met2 PF12907.2 AEO62964.1 - 0.042 13.8 1.4 0.09 12.7 0.1 2.2 2 0 0 2 2 2 0 Zinc-binding DUF605 PF04652.11 AEO62964.1 - 0.053 12.9 12.2 0.06 12.7 8.5 1.1 1 0 0 1 1 1 0 Vta1 like Nudix_N_2 PF14803.1 AEO62964.1 - 0.23 11.1 4.0 0.3 10.7 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal OrfB_Zn_ribbon PF07282.6 AEO62964.1 - 0.74 9.5 4.6 12 5.6 0.2 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain PAT1 PF09770.4 AEO62964.1 - 0.81 7.8 9.1 0.79 7.8 6.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2387 PF09526.5 AEO62964.1 - 1.1 9.2 6.3 1.4 8.9 1.2 2.8 2 1 1 3 3 3 0 Probable metal-binding protein (DUF2387) BAF1_ABF1 PF04684.8 AEO62964.1 - 4.7 5.9 8.8 5.6 5.7 6.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Fig1 PF12351.3 AEO62966.1 - 3.7e-21 75.8 0.6 3.7e-21 75.8 0.4 1.7 1 1 1 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 AEO62966.1 - 5.7e-08 32.5 1.7 7.4e-08 32.2 1.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Herpes_BLLF1 PF05109.8 AEO62967.1 - 0.27 9.1 16.0 0.35 8.7 11.1 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF4215 PF13948.1 AEO62967.1 - 0.76 10.0 3.7 1.3 9.2 2.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4215) Hamartin PF04388.7 AEO62967.1 - 3.9 6.0 6.6 4.9 5.7 4.5 1.0 1 0 0 1 1 1 0 Hamartin protein DUF2613 PF11021.3 AEO62968.1 - 0.011 15.4 0.0 0.041 13.6 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Glyco_hydro_11 PF00457.12 AEO62969.1 - 3.7e-52 176.3 19.3 4.6e-52 176.0 13.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 W_rich_C PF07483.6 AEO62969.1 - 0.069 12.8 3.5 0.16 11.6 2.4 1.7 1 0 0 1 1 1 0 Tryptophan-rich Synechocystis species C-terminal domain VWA_3 PF13768.1 AEO62971.1 - 2.1e-27 95.7 0.0 7.4e-27 93.9 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.5 AEO62971.1 - 1.2e-17 63.7 0.0 2.3e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 AEO62971.1 - 7.3e-10 39.2 0.0 1.2e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 AEO62971.1 - 7.4e-08 31.7 0.0 2.6e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 AEO62971.1 - 0.0026 17.5 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 AEO62971.1 - 0.0038 17.0 0.0 0.0083 15.9 0.0 1.5 1 1 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 AEO62971.1 - 0.0062 15.6 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Inhibitor_I24 PF10465.4 AEO62971.1 - 0.032 13.9 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 PinA peptidase inhibitor DUF2201 PF09967.4 AEO62971.1 - 0.042 13.8 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 VWA-like domain (DUF2201) Glycos_transf_2 PF00535.21 AEO62971.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Choline_transpo PF04515.7 AEO62973.1 - 1.5e-102 342.7 18.1 1.5e-102 342.7 12.6 2.2 2 0 0 2 2 2 2 Plasma-membrane choline transporter DUF4191 PF13829.1 AEO62973.1 - 0.11 11.5 7.1 0.033 13.3 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Pkinase PF00069.20 AEO62974.1 - 4.8e-26 91.4 0.0 1.9e-25 89.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO62974.1 - 8.3e-10 38.1 0.0 0.011 14.7 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 AEO62974.1 - 0.00082 18.4 0.0 1.1 8.0 0.0 2.7 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 AEO62974.1 - 0.0026 17.5 0.1 0.0026 17.5 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO62974.1 - 0.011 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA-synt_1c PF00749.16 AEO62975.1 - 7.1e-101 336.9 0.1 9.3e-101 336.6 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 AEO62975.1 - 2e-40 138.2 0.0 9e-40 136.1 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 AEO62975.1 - 0.0029 16.7 0.2 0.006 15.7 0.1 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Ribosomal_L1 PF00687.16 AEO62976.1 - 1.8e-24 86.2 0.0 2.2e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family COG2 PF06148.6 AEO62977.1 - 3.5e-21 75.4 0.0 5.9e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 AEO62977.1 - 0.0037 17.0 0.0 0.0094 15.7 0.0 1.8 1 1 0 1 1 1 1 Vps51/Vps67 Transposase_22 PF02994.9 AEO62977.1 - 0.013 14.0 0.0 0.018 13.5 0.0 1.2 1 0 0 1 1 1 0 L1 transposable element COG5 PF10392.4 AEO62977.1 - 0.044 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF2450 PF10475.4 AEO62977.1 - 0.072 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Sigma70_ner PF04546.8 AEO62977.1 - 0.13 11.9 6.2 2.2 7.8 0.8 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region BUD22 PF09073.5 AEO62977.1 - 1.7 7.6 9.5 0.27 10.2 2.6 2.0 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.7 AEO62977.1 - 2.6 5.8 14.3 0.81 7.5 6.1 2.0 2 0 0 2 2 2 0 Nop14-like family Hap4_Hap_bind PF10297.4 AEO62978.1 - 6.7e-09 35.2 7.1 6.7e-09 35.2 4.9 2.8 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 AEO62978.1 - 4.7e-06 26.4 14.2 0.00015 21.6 5.4 2.3 1 1 1 2 2 2 2 bZIP transcription factor CASP_C PF08172.7 AEO62978.1 - 0.035 13.1 0.1 0.067 12.2 0.1 1.4 1 0 0 1 1 1 0 CASP C terminal BBP1_C PF15272.1 AEO62978.1 - 0.066 12.7 1.7 0.1 12.1 1.2 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Cortex-I_coil PF09304.5 AEO62978.1 - 0.35 10.9 5.9 0.58 10.2 4.1 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil bZIP_Maf PF03131.12 AEO62978.1 - 0.57 10.5 7.8 0.94 9.8 5.4 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Fmp27_WPPW PF10359.4 AEO62978.1 - 1.5 7.1 3.3 2.1 6.6 2.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TEX13 PF15186.1 AEO62978.1 - 1.5 8.3 5.3 2.4 7.6 3.6 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family bZIP_2 PF07716.10 AEO62978.1 - 2.9 7.7 15.1 7.9 6.3 6.1 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Herpes_US12 PF05363.7 AEO62979.1 - 0.00068 20.0 0.3 0.093 13.2 0.0 3.0 2 0 0 2 2 2 2 Herpesvirus US12 family B3_4 PF03483.12 AEO62980.1 - 8.1e-26 90.5 0.1 1.3e-25 89.8 0.1 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 AEO62980.1 - 1.8e-13 50.1 0.0 3.7e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase B5 domain MFS_1 PF07690.11 AEO62981.1 - 1.3e-36 126.1 47.5 1.3e-36 126.1 32.9 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO62981.1 - 2e-12 46.1 11.9 3.6e-12 45.2 8.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 AEO62982.1 - 8.4e-27 93.7 27.6 8.4e-27 93.7 19.1 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Rrp15p PF07890.7 AEO62984.1 - 5e-35 120.3 11.9 5e-35 120.3 8.3 1.7 2 0 0 2 2 2 1 Rrp15p DUF605 PF04652.11 AEO62984.1 - 0.056 12.8 16.5 0.071 12.4 11.5 1.1 1 0 0 1 1 1 0 Vta1 like Fer2 PF00111.22 AEO62985.1 - 3.4e-12 45.9 0.8 4.9e-12 45.4 0.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HAD_2 PF13419.1 AEO62985.1 - 0.015 15.5 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Mito_carr PF00153.22 AEO62986.1 - 7.8e-16 57.5 4.0 0.016 14.9 0.0 6.0 4 1 1 5 5 5 5 Mitochondrial carrier protein adh_short PF00106.20 AEO62987.1 - 2.7e-11 43.6 0.6 4e-11 43.1 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO62987.1 - 0.0036 16.9 0.0 0.0076 15.9 0.0 1.5 1 0 0 1 1 1 1 KR domain LysM PF01476.15 AEO62989.1 - 1.1e-18 66.8 1.1 0.0045 16.8 0.0 5.8 5 0 0 5 5 5 5 LysM domain HTH_28 PF13518.1 AEO62989.1 - 0.021 14.8 0.0 3.2 7.8 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 AEO62989.1 - 0.036 14.0 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 Transposase Glyco_hydro_18 PF00704.23 AEO62990.1 - 1e-73 248.7 6.0 1.6e-73 248.1 4.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DNase_NucA_NucB PF14040.1 AEO62990.1 - 0.0024 17.9 0.0 0.028 14.5 0.0 2.5 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB Chitin_bind_1 PF00187.14 AEO62990.1 - 0.0025 17.7 19.6 0.0025 17.7 13.6 5.1 5 1 0 5 5 5 2 Chitin recognition protein Gly_transf_sug PF04488.10 AEO62991.1 - 1.4e-14 54.2 0.1 2.4e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 AEO62991.1 - 0.043 12.9 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 AEO62991.1 - 0.088 11.2 0.4 8.4 4.7 0.0 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Cortexin PF11057.3 AEO62991.1 - 0.14 11.7 0.2 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 Cortexin of kidney Sarcolipin PF05366.6 AEO62991.1 - 1.4 8.3 3.9 0.48 9.8 0.6 1.8 2 0 0 2 2 2 0 Sarcolipin Fringe PF02434.11 AEO62992.1 - 3.2e-07 29.8 0.0 2.5e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.21 AEO62992.1 - 0.00012 21.7 0.1 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 PAN domain Galactosyl_T PF01762.16 AEO62992.1 - 0.0074 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase PAN_2 PF08276.6 AEO62992.1 - 0.095 12.5 0.3 0.2 11.5 0.2 1.5 1 0 0 1 1 1 0 PAN-like domain PCI_Csn8 PF10075.4 AEO62992.1 - 0.19 11.4 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Voldacs PF03517.8 AEO62993.1 - 2e-23 82.7 0.0 3.7e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling TFIIA PF03153.8 AEO62994.1 - 0.57 10.0 2.3 0.62 9.8 1.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MSP1_C PF07462.6 AEO62994.1 - 4.5 5.5 7.1 5.1 5.3 4.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Prp19_bind PF06991.6 AEO62996.1 - 6.9e-54 182.9 27.7 6.9e-54 182.9 19.2 3.3 2 2 2 4 4 4 1 Splicing factor, Prp19-binding domain DNA_pol_E_B PF04042.11 AEO62997.1 - 4.3e-41 140.4 0.0 5.8e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 AEO62997.1 - 1.1e-30 107.0 0.0 1.5e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal CRAL_TRIO PF00650.15 AEO62998.1 - 5e-40 136.5 0.0 7.8e-40 135.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AEO62998.1 - 4e-09 36.4 0.3 9.7e-09 35.2 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AEO62998.1 - 0.0053 16.6 0.0 0.0076 16.1 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1510 PF07423.6 AEO62998.1 - 1.4 8.1 24.3 2.2 7.5 16.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Tim54 PF11711.3 AEO62998.1 - 2.3 6.7 15.5 0.66 8.5 8.1 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.7 AEO62998.1 - 3.3 7.5 20.0 7.1 6.4 13.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 AEO62998.1 - 3.5 7.3 13.6 6 6.5 9.5 1.4 1 0 0 1 1 1 0 DDHD domain DUF1675 PF07897.6 AEO62998.1 - 3.8 7.3 13.1 6 6.6 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) FLO_LFY PF01698.11 AEO62998.1 - 7.7 5.2 13.1 12 4.6 9.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Peptidase_S64 PF08192.6 AEO62998.1 - 8.7 4.5 10.0 12 4.1 6.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Hid1 PF12722.2 AEO62998.1 - 9 3.8 13.1 12 3.4 9.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Borrelia_P83 PF05262.6 AEO62998.1 - 9.2 4.4 19.0 13 3.9 13.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Bud13 PF09736.4 AEO62998.1 - 9.6 6.4 19.1 24 5.1 13.2 1.6 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex E1-E2_ATPase PF00122.15 AEO62999.1 - 3.3e-18 65.5 0.0 7.9e-18 64.3 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AEO62999.1 - 1.2e-17 65.0 0.0 1.7e-16 61.3 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AEO62999.1 - 1.3e-12 48.2 0.0 1.2e-11 45.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO62999.1 - 4.7e-12 45.7 0.0 1.8e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AEO62999.1 - 0.0018 17.8 0.0 0.013 15.0 0.0 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AEO62999.1 - 0.031 14.4 0.0 0.09 12.9 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 AEO62999.1 - 0.096 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Homeobox PF00046.24 AEO63000.1 - 4.1e-20 71.1 4.2 8.3e-20 70.1 2.9 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 AEO63000.1 - 0.00019 21.0 0.5 0.00067 19.3 0.4 2.0 1 0 0 1 1 1 1 Homeobox KN domain Adaptin_binding PF10199.4 AEO63001.1 - 6.6e-21 75.0 2.3 9.8e-21 74.4 1.6 1.3 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Fungal_trans PF04082.13 AEO63002.1 - 3e-22 78.7 0.0 4.7e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO63002.1 - 7.9e-09 35.2 8.8 1.7e-08 34.2 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IPPT PF01715.12 AEO63003.1 - 2.8e-53 180.5 0.2 4.4e-53 179.8 0.1 1.3 1 0 0 1 1 1 1 IPP transferase zf-C2H2_jaz PF12171.3 AEO63003.1 - 2.1e-06 27.6 0.2 3.9e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO63003.1 - 4.1e-05 23.6 0.4 7.1e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Ring_hydroxyl_A PF00848.14 AEO63003.1 - 0.02 14.5 0.6 1.2 8.6 0.1 2.3 1 1 1 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) SecY PF00344.15 AEO63004.1 - 1.6e-96 323.2 10.1 2.1e-96 322.8 7.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 AEO63004.1 - 1.1e-18 66.4 0.4 7.2e-18 63.8 0.2 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p RseC_MucC PF04246.7 AEO63004.1 - 3.3 7.2 5.0 0.82 9.2 0.0 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF3292 PF11696.3 AEO63005.1 - 5.7e-74 249.1 0.0 4.8e-72 242.8 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) DUF3292 PF11696.3 AEO63006.1 - 2.8e-33 114.7 2.1 3.1e-33 114.5 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) ABC_tran PF00005.22 AEO63008.1 - 2.3e-52 176.9 0.0 5.7e-30 104.3 0.0 2.7 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AEO63008.1 - 2.7e-47 161.4 16.9 1.8e-24 86.6 4.9 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_23 PF13476.1 AEO63008.1 - 1.7e-09 38.2 0.0 3.5e-05 24.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 AEO63008.1 - 1.3e-08 34.3 3.2 0.012 14.8 0.3 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AEO63008.1 - 2.3e-08 34.3 0.3 0.13 12.2 0.0 3.8 3 0 0 3 3 3 3 AAA domain T2SE PF00437.15 AEO63008.1 - 2.6e-06 26.5 0.1 0.013 14.4 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 AEO63008.1 - 7.4e-06 25.6 0.2 0.043 13.2 0.0 3.4 3 1 0 4 4 3 2 AAA-like domain AAA_29 PF13555.1 AEO63008.1 - 9.2e-06 25.1 0.3 0.087 12.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 AEO63008.1 - 6.1e-05 22.5 0.0 0.34 10.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AEO63008.1 - 7.3e-05 22.8 2.4 0.073 13.0 0.7 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 AEO63008.1 - 0.00014 22.0 0.5 3.2 7.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 AEO63008.1 - 0.0004 21.1 0.0 1.8 9.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 AEO63008.1 - 0.00042 20.2 1.0 0.022 14.5 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 AEO63008.1 - 0.00053 19.1 0.5 0.63 9.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin DUF258 PF03193.11 AEO63008.1 - 0.00056 19.1 0.0 0.88 8.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 AEO63008.1 - 0.00066 19.1 0.0 0.27 10.6 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein MobB PF03205.9 AEO63008.1 - 0.0016 18.1 0.1 1.6 8.4 0.0 3.3 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 AEO63008.1 - 0.0021 17.9 0.4 0.18 11.7 0.1 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 AEO63008.1 - 0.0039 17.4 0.4 3.5 7.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 AEO63008.1 - 0.006 17.0 0.1 6.6 7.2 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein ResIII PF04851.10 AEO63008.1 - 0.0093 15.8 0.3 7.8 6.2 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 AEO63008.1 - 0.015 15.0 0.4 0.93 9.2 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 AEO63008.1 - 0.022 14.3 4.9 7.7 6.0 0.2 3.5 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 AEO63008.1 - 0.029 14.5 0.2 8.4 6.6 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 AEO63008.1 - 0.045 13.2 0.1 4.4 6.7 0.1 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 AEO63008.1 - 0.046 13.4 0.0 0.77 9.4 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase TrwB_AAD_bind PF10412.4 AEO63008.1 - 0.065 11.8 2.9 3.2 6.2 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 AEO63008.1 - 0.088 11.7 0.1 10 4.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.18 AEO63008.1 - 0.09 12.5 0.5 8.8 6.1 0.0 2.8 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.17 AEO63008.1 - 0.11 12.6 0.3 20 5.4 0.0 3.0 3 0 0 3 3 2 0 RNA helicase NB-ARC PF00931.17 AEO63008.1 - 0.17 10.6 1.2 0.36 9.6 0.0 2.1 3 0 0 3 3 3 0 NB-ARC domain cobW PF02492.14 AEO63008.1 - 0.21 11.0 1.6 1.4 8.3 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 AEO63008.1 - 0.29 10.3 0.3 7.4 5.7 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Sugar_tr PF00083.19 AEO63010.1 - 1.4e-110 370.0 25.8 1.6e-110 369.7 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO63010.1 - 7.7e-22 77.4 32.4 8.2e-18 64.2 17.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 AEO63010.1 - 0.033 13.6 12.8 0.092 12.2 0.8 3.2 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 Zn_clus PF00172.13 AEO63011.1 - 1.6e-07 31.1 6.9 3.6e-07 29.9 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO63011.1 - 5.6e-07 28.6 0.0 1.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3439 PF11921.3 AEO63011.1 - 0.15 11.8 15.4 0.29 10.8 10.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 AEO63011.1 - 7.6 4.3 15.7 11 3.8 10.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NmrA PF05368.8 AEO63012.1 - 7e-27 94.1 0.0 9.2e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO63012.1 - 7.4e-18 65.1 0.3 1.4e-17 64.3 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 AEO63012.1 - 7.5e-05 21.8 0.0 0.0001 21.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 AEO63012.1 - 0.00028 20.8 0.2 0.00063 19.7 0.2 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO63012.1 - 0.00037 20.2 0.1 0.00071 19.2 0.1 1.5 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 AEO63012.1 - 0.00038 20.5 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 AEO63012.1 - 0.00073 19.9 0.1 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 AEO63012.1 - 0.0018 16.9 0.0 0.0035 16.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AEO63012.1 - 0.0025 17.2 0.3 0.0061 16.0 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 AEO63012.1 - 0.023 14.7 1.1 0.032 14.2 0.2 1.7 2 0 0 2 2 2 0 TrkA-N domain Polysacc_synt_2 PF02719.10 AEO63012.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TRIC PF05197.8 AEO63013.1 - 0.048 13.0 0.2 0.068 12.5 0.1 1.2 1 0 0 1 1 1 0 TRIC channel IER PF05760.7 AEO63013.1 - 0.2 11.5 2.4 0.24 11.2 1.7 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) Apc13p PF05839.6 AEO63014.1 - 1.4e-37 127.5 0.0 1.6e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.11 AEO63015.1 - 2.9e-37 127.5 0.0 3.4e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SGS PF05002.10 AEO63016.1 - 6.2e-29 99.5 2.1 1.3e-28 98.5 1.5 1.6 1 0 0 1 1 1 1 SGS domain CS PF04969.11 AEO63016.1 - 2.3e-15 56.8 0.0 3.5e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 AEO63016.1 - 6.6e-09 35.2 2.2 1.2e-07 31.2 1.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 AEO63016.1 - 2.7e-06 26.8 5.5 0.91 9.5 0.6 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 AEO63016.1 - 4.9e-05 23.8 9.1 0.00073 20.1 3.7 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 AEO63016.1 - 0.00025 20.5 1.3 1.8 8.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 AEO63016.1 - 0.0007 19.4 4.9 0.62 10.0 1.6 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO63016.1 - 0.0087 15.7 1.8 12 5.9 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 AEO63016.1 - 0.01 15.9 0.7 0.022 14.9 0.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AEO63016.1 - 0.05 13.4 3.6 0.15 11.9 2.1 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 AEO63016.1 - 0.073 13.4 1.2 0.47 10.8 0.8 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO63016.1 - 1.7 9.4 5.5 9.8 7.1 0.4 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Glyco_transf_21 PF13506.1 AEO63017.1 - 2.5e-11 43.1 0.0 7.6e-05 22.0 0.0 3.5 2 1 1 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 AEO63017.1 - 1.6e-10 41.1 0.0 4e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 AEO63017.1 - 0.12 12.0 0.0 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 TauD PF02668.11 AEO63019.1 - 8.5e-23 81.3 0.0 2.1e-22 80.0 0.0 1.7 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1949 PF09186.6 AEO63019.1 - 0.098 12.2 0.2 0.51 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) tRNA_int_endo PF01974.12 AEO63023.1 - 2.9e-20 71.8 0.0 6.2e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 AEO63023.1 - 2.9e-06 26.7 0.0 0.003 17.0 0.0 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain ABC_tran PF00005.22 AEO63024.1 - 2.9e-38 131.2 0.0 8.5e-19 68.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AEO63024.1 - 1.5e-23 83.6 25.5 1.9e-16 60.2 11.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 AEO63024.1 - 6.4e-10 39.4 0.0 0.9 9.4 0.0 4.4 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 AEO63024.1 - 7.5e-07 28.6 0.2 2.5 7.2 0.0 4.7 4 1 1 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 AEO63024.1 - 1.3e-06 28.3 0.5 0.0073 16.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 AEO63024.1 - 2.9e-05 23.5 0.4 0.1 12.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 AEO63024.1 - 4e-05 24.4 0.5 0.3 11.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 AEO63024.1 - 0.0005 20.2 0.1 1.6 8.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 AEO63024.1 - 0.00051 19.9 0.0 0.39 10.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 AEO63024.1 - 0.00061 19.3 0.0 0.73 9.2 0.0 2.9 3 0 0 3 3 3 2 AAA-like domain MobB PF03205.9 AEO63024.1 - 0.00081 19.1 0.1 0.36 10.5 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 AEO63024.1 - 0.00091 19.2 0.5 2 8.3 0.3 2.6 2 0 0 2 2 2 2 AAA ATPase domain Sigma70_ECF PF07638.6 AEO63024.1 - 0.0028 17.3 1.2 0.0051 16.4 0.8 1.3 1 0 0 1 1 1 1 ECF sigma factor Miro PF08477.8 AEO63024.1 - 0.0032 17.9 0.0 0.13 12.7 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein K_channel_TID PF07941.6 AEO63024.1 - 0.0032 17.6 2.4 0.0077 16.4 1.7 1.6 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain AAA_25 PF13481.1 AEO63024.1 - 0.005 16.2 0.3 3.4 7.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 AEO63024.1 - 0.0062 15.7 0.2 1.5 7.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 AEO63024.1 - 0.0098 15.7 0.9 2.2 8.0 0.0 2.3 2 0 0 2 2 2 1 Dynamin family Mg_chelatase PF01078.16 AEO63024.1 - 0.017 14.2 0.2 0.35 9.9 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 AEO63024.1 - 0.03 14.6 5.6 0.77 10.0 0.0 3.2 3 0 0 3 3 2 0 AAA domain T2SE PF00437.15 AEO63024.1 - 0.037 12.9 0.0 0.36 9.7 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 AEO63024.1 - 0.038 13.4 0.0 0.42 10.0 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 AEO63024.1 - 0.14 12.0 0.2 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_23 PF13476.1 AEO63024.1 - 0.38 11.0 0.1 38 4.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain PS_Dcarbxylase PF02666.10 AEO63025.1 - 7.9e-33 113.4 0.1 9.9e-33 113.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSD3 PF07626.6 AEO63026.1 - 0.038 13.9 0.1 0.094 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1587) Nitr_red_bet_C PF14711.1 AEO63026.1 - 0.068 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal DUF1087 PF06465.8 AEO63026.1 - 0.1 12.5 0.6 0.19 11.6 0.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) Pkinase PF00069.20 AEO63027.1 - 4.9e-29 101.2 0.0 7.6e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO63027.1 - 1.4e-09 37.3 0.0 2.6e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO63027.1 - 8.3e-06 25.7 0.2 2.4e-05 24.1 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 AEO63027.1 - 4.8e-05 22.4 0.0 9.5e-05 21.4 0.0 1.4 2 0 0 2 2 2 1 Kinase-like COesterase PF00135.23 AEO63028.1 - 2.1e-87 294.0 0.0 3.2e-87 293.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO63028.1 - 3.4e-07 30.0 0.3 1.8e-06 27.6 0.1 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AEO63028.1 - 0.048 12.8 0.0 0.048 12.8 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO63028.1 - 0.13 12.0 0.0 0.13 12.0 0.0 2.0 2 1 0 2 2 2 0 Alpha/beta hydrolase family Fungal_trans PF04082.13 AEO63029.1 - 2.9e-50 170.5 0.0 3.9e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.18 AEO63030.1 - 2.8e-24 85.1 4.2 2.8e-24 85.1 2.9 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 AEO63030.1 - 0.00028 20.7 0.3 0.00053 19.8 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like SPC12 PF06645.8 AEO63030.1 - 0.19 11.5 0.8 0.48 10.2 0.0 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) GFA PF04828.9 AEO63031.1 - 1.1e-18 66.9 0.8 1.7e-18 66.3 0.6 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-B_box PF00643.19 AEO63031.1 - 0.13 12.2 0.6 0.13 12.2 0.4 2.8 3 0 0 3 3 3 0 B-box zinc finger Cys_rich_CWC PF14375.1 AEO63031.1 - 1.3 8.9 6.2 0.34 10.8 1.2 2.1 2 0 0 2 2 2 0 Cysteine-rich CWC FYVE PF01363.16 AEO63031.1 - 3.2 7.7 8.1 7.1 6.6 4.4 2.3 1 1 0 1 1 1 0 FYVE zinc finger CorA PF01544.13 AEO63032.1 - 6.6e-06 25.3 2.7 1e-05 24.7 1.9 1.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Dispanin PF04505.7 AEO63032.1 - 0.1 12.1 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Interferon-induced transmembrane protein FAD_binding_4 PF01565.18 AEO63034.1 - 1.3e-19 70.0 1.4 3.4e-19 68.7 1.0 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO63034.1 - 1.5e-10 40.7 0.7 3.2e-10 39.7 0.5 1.5 1 0 0 1 1 1 1 Berberine and berberine like Transport_MerF PF11431.3 AEO63035.1 - 0.023 14.3 1.4 0.023 14.3 0.9 2.7 3 0 0 3 3 3 0 Membrane transport protein MerF Cation_ATPase_C PF00689.16 AEO63035.1 - 0.037 13.5 0.6 0.037 13.5 0.4 2.7 1 1 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF4509 PF14970.1 AEO63036.1 - 0.25 10.9 4.0 0.45 10.1 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) DEAD PF00270.24 AEO63037.1 - 9.1e-40 135.9 0.0 1.8e-39 134.9 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO63037.1 - 3.1e-21 75.0 0.0 9.5e-20 70.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO63037.1 - 0.0002 21.2 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 AEO63037.1 - 0.043 12.7 0.0 0.13 11.2 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 AEO63037.1 - 0.05 13.3 0.6 0.75 9.5 0.0 3.0 4 0 0 4 4 4 0 Part of AAA domain AAA_30 PF13604.1 AEO63037.1 - 0.14 11.6 0.0 0.35 10.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain OPT PF03169.10 AEO63038.1 - 3.1e-180 600.7 50.3 3.5e-180 600.5 34.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_C48 PF02902.14 AEO63039.1 - 0.00066 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain rve PF00665.21 AEO63043.1 - 0.047 13.8 0.0 0.068 13.2 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.22 AEO63044.1 - 4e-06 26.3 0.3 5.5e-06 25.8 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_2 PF12796.2 AEO63045.1 - 7.7e-55 183.2 26.5 2.3e-16 59.9 0.0 11.8 6 3 4 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 AEO63045.1 - 2e-35 118.8 29.2 3.3e-05 23.4 0.0 16.8 20 0 0 20 20 20 8 Ankyrin repeat Ank_4 PF13637.1 AEO63045.1 - 3.8e-29 100.5 18.0 1.5e-05 25.3 0.0 13.3 9 6 6 15 15 15 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO63045.1 - 3.6e-26 88.6 21.9 0.0049 16.9 0.3 17.6 19 2 2 21 21 21 5 Ankyrin repeat Ank_5 PF13857.1 AEO63045.1 - 1.8e-16 59.7 18.7 2.7e-06 27.4 0.0 10.0 7 2 3 10 10 10 4 Ankyrin repeats (many copies) PBP PF01161.15 AEO63046.1 - 1.4e-25 89.8 0.2 1.8e-25 89.4 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Erythro_esteras PF05139.9 AEO63048.1 - 3e-147 490.3 3.5 3.6e-147 490.1 2.4 1.0 1 0 0 1 1 1 1 Erythromycin esterase Con-6 PF10346.4 AEO63049.1 - 2.3e-32 110.1 4.8 5.5e-17 60.8 0.5 2.5 2 0 0 2 2 2 2 Conidiation protein 6 Toxin_52 PF15605.1 AEO63049.1 - 0.023 14.5 0.9 0.43 10.4 0.1 2.2 2 0 0 2 2 2 0 Putative toxin 52 SpoIIIAH PF12685.2 AEO63049.1 - 0.21 11.0 11.9 0.3 10.5 6.2 1.9 1 1 1 2 2 2 0 SpoIIIAH-like protein SMP PF04927.7 AEO63050.1 - 8.4e-15 54.4 10.3 1.9e-08 34.1 0.0 2.1 1 1 1 2 2 2 2 Seed maturation protein Gtr1_RagA PF04670.7 AEO63052.1 - 1.1e-96 322.5 0.0 1.3e-96 322.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 AEO63052.1 - 2.6e-09 36.5 0.2 3.8e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 AEO63052.1 - 1.6e-08 34.1 0.1 2.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 AEO63052.1 - 4e-06 26.7 0.0 7.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AEO63052.1 - 3e-05 24.4 0.0 6.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 AEO63052.1 - 0.00089 18.7 0.3 0.0076 15.7 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 AEO63052.1 - 0.0091 16.2 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter DUF815 PF05673.8 AEO63052.1 - 0.01 14.7 0.1 0.021 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF258 PF03193.11 AEO63052.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 G-alpha PF00503.15 AEO63052.1 - 0.026 13.2 0.2 0.48 9.0 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit SEP PF08059.8 AEO63053.1 - 1.5e-26 92.4 0.1 3.1e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 AEO63053.1 - 4.1e-12 45.4 0.3 6.6e-12 44.7 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 AEO63053.1 - 1.3e-11 44.3 0.0 2.2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain Lipoprotein_19 PF13617.1 AEO63053.1 - 0.17 11.5 0.1 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 YnbE-like lipoprotein 60KD_IMP PF02096.15 AEO63054.1 - 4.5e-29 101.5 5.1 4.5e-29 101.5 3.5 1.4 2 0 0 2 2 2 1 60Kd inner membrane protein TOM13 PF08219.6 AEO63054.1 - 2.9e-28 97.4 0.0 6.4e-28 96.3 0.0 1.6 1 0 0 1 1 1 1 Outer membrane protein TOM13 Pro_CA PF00484.14 AEO63055.1 - 4.3e-25 88.4 0.0 5.6e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Ank_2 PF12796.2 AEO63056.1 - 1e-32 112.2 0.4 2.2e-10 40.7 0.0 4.9 3 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 AEO63056.1 - 2.4e-21 74.3 18.0 1.5e-07 30.8 0.0 9.3 9 2 0 9 9 9 5 Ankyrin repeat Ank_3 PF13606.1 AEO63056.1 - 9.8e-21 71.7 4.0 0.00013 21.8 0.0 8.6 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.1 AEO63056.1 - 3e-20 72.1 3.0 0.00061 20.2 0.0 6.5 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO63056.1 - 3.1e-19 68.5 7.0 7.7e-07 29.1 0.1 6.2 6 1 0 6 6 6 3 Ankyrin repeats (many copies) TFIIA PF03153.8 AEO63057.1 - 7.5 6.3 8.3 9.8 5.9 5.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAM_decarbox PF01536.11 AEO63058.1 - 1.3e-85 287.0 0.0 3.3e-83 279.1 0.0 3.1 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase ParA PF10609.4 AEO63059.1 - 5.6e-37 125.4 0.1 1.1e-36 124.5 0.1 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 AEO63059.1 - 5e-14 52.1 0.0 9.9e-14 51.1 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 AEO63059.1 - 2.7e-06 26.6 0.0 5e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 AEO63059.1 - 5.3e-05 22.4 1.6 6.1e-05 22.2 0.1 1.8 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 AEO63059.1 - 9.2e-05 22.4 0.1 0.0003 20.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 AEO63059.1 - 0.0015 17.4 0.5 0.0025 16.6 0.3 1.3 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 AEO63059.1 - 0.004 16.5 0.1 0.0075 15.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 AEO63059.1 - 0.034 13.5 0.6 0.06 12.6 0.4 1.6 1 1 0 1 1 1 0 YhjQ protein DUF258 PF03193.11 AEO63059.1 - 0.05 12.7 0.9 0.11 11.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_26 PF13500.1 AEO63059.1 - 0.06 12.9 0.4 5.5 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 AEO63059.1 - 0.12 11.9 0.1 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.1 AEO63059.1 - 0.29 11.0 1.2 0.61 10.0 0.4 1.7 2 0 0 2 2 2 0 AAA ATPase domain p450 PF00067.17 AEO63061.1 - 4.8e-93 312.1 0.0 5.5e-93 311.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_13 PF13166.1 AEO63062.1 - 0.052 12.0 0.0 0.11 10.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF883 PF05957.8 AEO63062.1 - 8.1 6.9 9.8 7.2 7.0 4.6 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4134 PF13572.1 AEO63063.1 - 0.12 12.5 0.3 0.12 12.5 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) MFS_1 PF07690.11 AEO63064.1 - 1e-43 149.3 49.1 1e-43 149.3 34.1 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO63064.1 - 1.5e-13 49.8 14.6 2.9e-13 48.9 10.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 AEO63064.1 - 4.9e-10 38.5 11.4 4.9e-10 38.5 7.9 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter ESSS PF10183.4 AEO63064.1 - 0.68 10.3 2.8 20 5.6 0.0 3.3 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) F-box-like PF12937.2 AEO63066.1 - 0.014 15.1 0.0 0.036 13.7 0.0 1.7 1 0 0 1 1 1 0 F-box-like Formyl_trans_N PF00551.14 AEO63067.1 - 2.1e-38 131.7 0.0 2.6e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase DUF2336 PF10098.4 AEO63067.1 - 0.00088 18.5 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2336) Sporozoite_P67 PF05642.6 AEO63068.1 - 5 4.8 13.5 8.1 4.1 9.3 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen 2-Hacid_dh_C PF02826.14 AEO63069.1 - 1.3e-36 125.4 0.0 2e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AEO63069.1 - 1.3e-09 37.6 0.0 1.9e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AEO63069.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AEO63069.1 - 0.018 15.4 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.20 AEO63070.1 - 1.3e-39 135.9 0.0 1.8e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO63070.1 - 1.2e-25 90.0 0.0 1.6e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 AEO63070.1 - 0.00018 21.5 0.0 0.00041 20.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 AEO63070.1 - 0.0003 19.8 0.0 0.0005 19.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO63070.1 - 0.0095 15.6 0.0 0.027 14.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Nop14 PF04147.7 AEO63075.1 - 0.17 9.7 12.7 0.28 9.0 8.8 1.3 1 0 0 1 1 1 0 Nop14-like family PBP_sp32 PF07222.7 AEO63075.1 - 0.18 10.9 4.7 0.32 10.1 3.3 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pox_Ag35 PF03286.9 AEO63075.1 - 0.7 9.3 18.8 0.022 14.2 6.3 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CDC27 PF09507.5 AEO63075.1 - 0.83 8.8 23.3 0.13 11.4 6.3 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 PBP1_TM PF14812.1 AEO63075.1 - 3.5 8.0 27.3 0.32 11.3 3.7 3.0 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PGA2 PF07543.7 AEO63075.1 - 5.2 6.8 15.4 2.4 7.9 8.5 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 Iron_permease PF04120.7 AEO63076.1 - 5.6e-38 129.5 4.7 6.6e-18 64.5 0.0 4.2 4 0 0 4 4 4 4 Low affinity iron permease DUF3767 PF12597.3 AEO63076.1 - 0.0053 16.4 0.5 0.55 9.9 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3767) DUF4149 PF13664.1 AEO63076.1 - 0.085 12.9 5.3 0.22 11.5 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) VirB3 PF05101.8 AEO63076.1 - 1.6 8.7 5.9 2.8 8.0 0.3 3.4 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein DLH PF01738.13 AEO63077.1 - 6.8e-18 64.7 0.0 1.3e-17 63.8 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AEO63077.1 - 3.1e-06 27.0 0.1 4.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO63077.1 - 0.0015 18.4 5.7 0.0072 16.2 2.3 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO63077.1 - 0.037 13.2 0.1 1.3 8.1 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family Glyco_hydro_47 PF01532.15 AEO63078.1 - 5.6e-170 565.8 0.0 6.4e-170 565.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TFIIA_gamma_N PF02268.11 AEO63079.1 - 4.9e-09 35.6 0.1 8.8e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 AEO63079.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit TauD PF02668.11 AEO63080.1 - 2.4e-28 99.5 0.0 3e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pept_tRNA_hydro PF01195.14 AEO63083.1 - 4.7e-30 104.4 0.0 5.6e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase BAR PF03114.13 AEO63084.1 - 2.1e-64 217.2 3.5 2.5e-64 216.9 2.5 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.10 AEO63084.1 - 0.07 13.6 0.2 0.54 10.7 0.0 2.5 3 0 0 3 3 3 0 CP12 domain BAR PF03114.13 AEO63085.1 - 1e-54 185.5 4.3 1.2e-54 185.2 3.0 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 AEO63085.1 - 3.8e-06 26.0 1.1 4.9e-06 25.6 0.8 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking IMD PF08397.6 AEO63085.1 - 0.013 14.8 1.7 0.013 14.8 1.2 2.0 2 0 0 2 2 2 0 IRSp53/MIM homology domain Myosin_tail_1 PF01576.14 AEO63085.1 - 0.041 11.5 10.5 0.11 10.1 5.1 2.0 2 0 0 2 2 2 0 Myosin tail Herpes_UL25 PF01499.11 AEO63085.1 - 0.045 12.0 1.1 0.058 11.7 0.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family IncA PF04156.9 AEO63085.1 - 0.43 10.1 8.8 0.74 9.3 6.1 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 AEO63085.1 - 0.53 9.2 9.5 0.91 8.4 6.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-Q PF13094.1 AEO63085.1 - 1.6 8.7 7.8 1.2 9.1 3.7 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Cyclin_N PF00134.18 AEO63086.1 - 8.9e-06 25.2 0.0 2.4e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AEO63086.1 - 3.2 7.7 4.5 13 5.6 0.0 3.2 4 0 0 4 4 4 0 Cyclin, C-terminal domain UQ_con PF00179.21 AEO63087.1 - 4.2e-26 91.0 0.0 5e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 AEO63087.1 - 0.0037 16.9 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 UEV domain Phosphoesterase PF04185.9 AEO63088.1 - 1.1e-69 235.4 0.2 2.1e-69 234.5 0.1 1.4 1 1 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.14 AEO63089.1 - 2.3e-36 125.2 7.0 3.8e-36 124.5 4.8 1.3 1 1 0 1 1 1 1 VIT family Chorion_2 PF03964.10 AEO63089.1 - 0.033 14.7 2.5 0.055 14.0 1.7 1.4 1 0 0 1 1 1 0 Chorion family 2 Ammonium_transp PF00909.16 AEO63090.1 - 6.2e-121 403.6 26.9 7e-121 403.4 18.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Fasciclin PF02469.17 AEO63091.1 - 3.2e-43 146.7 2.9 4.2e-24 84.9 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF4098 PF13345.1 AEO63091.1 - 0.37 10.7 4.3 4.1 7.4 0.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4098) Beta-lactamase PF00144.19 AEO63092.1 - 3.4e-35 121.6 0.2 7.3e-35 120.5 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase TMEM171 PF15471.1 AEO63092.1 - 7.7 5.2 8.3 12 4.5 5.7 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Exo_endo_phos PF03372.18 AEO63093.1 - 1.2e-16 61.4 0.1 2.3e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GP41 PF00517.12 AEO63094.1 - 0.0076 15.8 1.1 0.0099 15.4 0.8 1.1 1 0 0 1 1 1 1 Retroviral envelope protein DASH_Dam1 PF08653.5 AEO63094.1 - 0.061 13.0 1.6 0.87 9.4 0.2 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 Baculo_PEP_C PF04513.7 AEO63094.1 - 0.075 12.8 3.0 0.21 11.4 1.7 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Telomere_Sde2_2 PF13297.1 AEO63094.1 - 0.077 12.2 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Telomere stability C-terminal HpaB_N PF11794.3 AEO63094.1 - 0.089 12.1 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Fimbrial_CS1 PF04449.7 AEO63094.1 - 0.11 12.5 0.1 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 CS1 type fimbrial major subunit HET PF06985.6 AEO63096.1 - 3.9e-35 121.0 0.0 8.4e-35 119.9 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pollen_allerg_2 PF01620.11 AEO63096.1 - 0.17 12.1 0.9 0.37 11.1 0.6 1.4 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) APH PF01636.18 AEO63097.1 - 4.6e-08 33.0 0.1 6.1e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO63097.1 - 0.00021 20.9 0.0 0.00035 20.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase p450 PF00067.17 AEO63098.1 - 6.6e-59 199.6 0.0 8.5e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ArabFuran-catal PF09206.6 AEO63099.1 - 5e-159 528.4 23.5 7.4e-159 527.9 16.3 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 AEO63099.1 - 1e-25 90.0 2.0 1.4e-25 89.6 0.3 2.0 1 1 1 2 2 2 1 Alpha-L-arabinofuranosidase B (ABFB) Glyco_hydro_11 PF00457.12 AEO63100.1 - 6.1e-52 175.6 12.8 8.3e-52 175.1 8.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 AEO63100.1 - 3.6e-11 42.5 18.6 1.9e-10 40.2 12.9 2.4 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 AEO63100.1 - 0.00095 19.1 6.5 0.0019 18.2 4.5 1.5 1 0 0 1 1 1 1 Toxin 7 GST_N_3 PF13417.1 AEO63101.1 - 2e-09 37.5 0.0 4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO63101.1 - 1.1e-08 34.9 0.0 2.2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 AEO63101.1 - 3.3e-08 33.4 0.0 6.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AEO63101.1 - 8.6e-08 32.5 0.1 1.6e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AEO63101.1 - 9.1e-08 32.1 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO63101.1 - 1.2e-07 31.4 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Alpha-L-AF_C PF06964.7 AEO63102.1 - 2.3e-45 154.5 0.0 5.1e-45 153.4 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 AEO63102.1 - 1.4e-07 31.5 0.9 2.8e-07 30.6 0.6 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain Ribonuclease PF00545.15 AEO63105.1 - 6.3e-15 55.0 0.1 8.6e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 ribonuclease Defensin_big PF14862.1 AEO63105.1 - 0.024 14.7 0.4 0.042 13.9 0.3 1.4 1 0 0 1 1 1 0 Big defensin Swi5 PF07061.6 AEO63106.1 - 8.7e-23 79.9 0.0 1.7e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Swi5 DCP1 PF06058.8 AEO63106.1 - 4.8e-14 52.4 0.0 9.2e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family NSP2_assoc PF14758.1 AEO63106.1 - 0.019 15.0 0.1 0.046 13.8 0.1 1.5 1 1 0 1 1 1 0 Non-essential region of nsp2 of arterivirus polyprotein Mito_fiss_reg PF05308.6 AEO63106.1 - 0.62 9.3 3.5 1 8.6 2.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator BetaGal_dom4_5 PF13364.1 AEO63108.1 - 1.6e-07 31.5 0.0 3.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Sugar_tr PF00083.19 AEO63110.1 - 1.4e-68 231.5 16.8 1.6e-68 231.3 11.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO63110.1 - 5.3e-12 45.1 30.5 5.3e-12 45.1 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 AEO63111.1 - 7e-23 81.7 0.0 2.2e-22 80.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO63111.1 - 3e-05 23.9 0.1 0.00026 20.9 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 AEO63111.1 - 3.9e-05 22.7 0.0 0.00034 19.6 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 AEO63111.1 - 5.7e-05 21.5 0.0 0.0001 20.7 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 AEO63111.1 - 0.00038 20.4 0.2 2.2 8.1 0.1 4.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 AEO63111.1 - 0.0024 17.0 0.0 0.0073 15.4 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 AEO63111.1 - 0.0047 16.7 0.0 1 9.0 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 AEO63111.1 - 0.012 15.6 0.2 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Cyclase PF04199.8 AEO63112.1 - 2.8e-16 59.6 0.2 4.4e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase GST_C_3 PF14497.1 AEO63114.1 - 1.2e-08 35.3 0.0 1.9e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 AEO63114.1 - 0.019 14.8 0.7 0.034 14.0 0.5 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 AEO63114.1 - 0.025 14.8 0.0 0.12 12.6 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain F-box-like PF12937.2 AEO63115.1 - 2.2e-14 52.8 2.2 5.6e-14 51.5 0.5 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 AEO63115.1 - 2.2e-09 36.7 8.3 0.6 9.7 0.0 7.5 3 2 7 10 10 10 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO63115.1 - 3.5e-09 36.2 13.3 0.0022 17.6 0.3 6.9 5 2 2 7 7 7 3 Leucine rich repeat LRR_6 PF13516.1 AEO63115.1 - 1.1e-08 34.2 17.1 0.62 10.3 0.0 11.1 11 1 1 12 12 12 1 Leucine Rich repeat F-box PF00646.28 AEO63115.1 - 2.9e-06 26.7 0.1 1.3e-05 24.7 0.1 2.2 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.28 AEO63115.1 - 1.7e-05 24.1 25.1 1.9 8.7 0.0 10.3 9 3 0 9 9 9 1 Leucine Rich Repeat LRR_7 PF13504.1 AEO63115.1 - 2.6 8.6 32.8 26 5.6 0.1 10.1 9 2 1 10 10 10 0 Leucine rich repeat Ste50p-SAM PF09235.5 AEO63115.1 - 4.5 7.3 6.9 11 6.0 0.0 4.6 4 1 0 5 5 5 0 Ste50p, sterile alpha motif Chalcone PF02431.10 AEO63116.1 - 1.2e-62 210.8 0.0 1.6e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase BAG PF02179.11 AEO63117.1 - 1.1e-18 67.1 0.3 1.7e-18 66.4 0.2 1.3 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 AEO63117.1 - 0.0071 15.7 0.0 0.017 14.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L13 PF00572.13 AEO63118.1 - 5.3e-28 97.6 0.0 9.8e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.15 AEO63118.1 - 0.068 12.7 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain RVT_1 PF00078.22 AEO63119.1 - 0.0098 15.2 0.8 0.013 14.8 0.5 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Utp12 PF04003.7 AEO63119.1 - 0.045 13.6 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family Not3 PF04065.10 AEO63119.1 - 0.069 12.4 0.9 0.11 11.8 0.7 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component EF-hand_8 PF13833.1 AEO63119.1 - 0.12 11.9 0.1 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Imm8 PF15560.1 AEO63119.1 - 0.16 11.6 3.3 0.18 11.4 0.5 1.9 1 1 1 2 2 2 0 Immunity protein 8 AAA PF00004.24 AEO63120.1 - 3.4e-41 140.5 0.0 6.2e-41 139.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO63120.1 - 5.4e-07 29.8 0.1 0.00019 21.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 AEO63120.1 - 2e-06 27.8 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 AEO63120.1 - 1.1e-05 24.5 0.0 1.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 AEO63120.1 - 3.8e-05 23.4 0.1 0.00013 21.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AEO63120.1 - 0.00019 21.4 0.1 0.001 19.1 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 AEO63120.1 - 0.00034 19.7 0.0 0.00063 18.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 AEO63120.1 - 0.00092 19.2 0.3 0.004 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AEO63120.1 - 0.0022 17.9 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 AEO63120.1 - 0.0038 16.8 0.2 0.35 10.5 0.0 2.7 2 1 1 3 3 3 1 NACHT domain AAA_19 PF13245.1 AEO63120.1 - 0.0062 16.2 0.3 0.015 15.0 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 AEO63120.1 - 0.0067 15.8 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 AEO63120.1 - 0.0068 17.2 1.1 0.011 16.5 0.1 2.0 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 AEO63120.1 - 0.0082 16.0 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AEO63120.1 - 0.0089 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 AEO63120.1 - 0.01 16.1 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 AEO63120.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 AEO63120.1 - 0.015 14.5 1.9 0.21 10.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein TIP49 PF06068.8 AEO63120.1 - 0.019 13.6 0.1 0.045 12.4 0.1 1.6 1 1 0 1 1 1 0 TIP49 C-terminus NB-ARC PF00931.17 AEO63120.1 - 0.038 12.8 0.0 0.064 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 AEO63120.1 - 0.04 13.0 0.2 0.43 9.6 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.17 AEO63120.1 - 0.045 13.9 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 AEO63120.1 - 0.051 13.1 0.2 0.14 11.7 0.2 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 AEO63120.1 - 0.053 12.6 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 AEO63120.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 AEO63120.1 - 0.21 11.8 1.1 0.77 10.0 0.2 2.5 2 1 0 2 2 1 0 ABC transporter AAA_25 PF13481.1 AEO63120.1 - 0.23 10.8 5.6 0.26 10.6 0.3 2.6 2 1 0 3 3 3 0 AAA domain UQ_con PF00179.21 AEO63121.1 - 1.1e-39 135.0 0.0 1.4e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 AEO63121.1 - 3.8e-07 29.5 0.1 6.5e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 AEO63121.1 - 5.4e-05 22.9 0.0 8.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 AEO63121.1 - 0.059 13.0 0.1 0.086 12.5 0.1 1.3 1 0 0 1 1 1 0 UEV domain CoA_binding PF02629.14 AEO63122.1 - 3e-27 94.9 4.6 1.9e-26 92.3 0.8 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 AEO63122.1 - 4.4e-24 84.8 0.2 7.3e-24 84.1 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 AEO63122.1 - 1.8e-08 34.1 0.0 2.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 AEO63122.1 - 0.00041 20.4 0.1 0.0014 18.8 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 AEO63122.1 - 0.023 15.2 0.1 0.049 14.1 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Radical_SAM PF04055.16 AEO63123.1 - 1.1e-16 61.4 0.1 4.1e-16 59.6 0.0 1.9 2 1 1 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 AEO63123.1 - 1.6e-12 47.2 0.0 9.7e-12 44.7 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Sugar_tr PF00083.19 AEO63126.1 - 0.004 15.7 0.1 0.0047 15.5 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO63126.1 - 0.019 13.6 0.1 0.025 13.2 0.1 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily MUG113 PF13455.1 AEO63127.1 - 8.7e-32 109.4 0.1 1.8e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 AEO63127.1 - 1.9e-23 82.7 0.0 4.7e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain DUF1875 PF08961.5 AEO63127.1 - 0.036 13.3 0.1 0.069 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) FTP PF07504.8 AEO63128.1 - 0.038 13.4 0.7 0.11 11.9 0.2 1.9 2 0 0 2 2 2 0 Fungalysin/Thermolysin Propeptide Motif Sod_Fe_N PF00081.17 AEO63129.1 - 2.1e-34 117.5 1.2 2.1e-34 117.5 0.9 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 AEO63129.1 - 2.5e-34 117.2 1.2 3.5e-34 116.8 0.2 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain RP1-2 PF12042.3 AEO63129.1 - 2.9 7.5 10.2 0.86 9.2 1.4 2.6 2 1 1 3 3 3 0 Tubuliform egg casing silk strands structural domain MBOAT_2 PF13813.1 AEO63131.1 - 5e-19 68.1 3.1 1.2e-18 66.9 2.2 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family CVNH PF08881.5 AEO63132.1 - 6e-11 42.4 0.1 1e-10 41.7 0.0 1.5 1 1 0 1 1 1 1 CVNH domain DUF2305 PF10230.4 AEO63133.1 - 1.8e-62 211.1 0.0 2.1e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 AEO63133.1 - 3.7e-08 33.5 0.3 5.3e-08 33.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO63133.1 - 0.013 15.2 0.0 0.018 14.7 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 AEO63133.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Sld5 PF05916.6 AEO63133.1 - 0.14 12.4 0.6 0.33 11.2 0.4 1.7 1 1 0 1 1 1 0 GINS complex protein S1FA PF04689.8 AEO63134.1 - 0.016 15.1 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 DNA binding protein S1FA RCR PF12273.3 AEO63134.1 - 0.097 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red ABC_tran PF00005.22 AEO63135.1 - 1e-47 161.8 0.0 8.7e-24 84.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 AEO63135.1 - 7.2e-22 77.0 2.4 7.2e-22 77.0 1.7 3.3 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 AEO63135.1 - 1.5e-19 71.0 0.0 2.4e-05 24.4 0.0 4.2 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 AEO63135.1 - 1.6e-09 37.3 0.2 0.41 9.8 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AEO63135.1 - 1.8e-09 36.9 0.1 0.00091 18.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 AEO63135.1 - 2.1e-08 34.7 4.1 0.03 14.6 0.1 3.5 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 AEO63135.1 - 3.5e-07 29.5 0.0 0.00061 19.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 AEO63135.1 - 4.6e-07 30.1 0.3 0.022 15.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 AEO63135.1 - 6.6e-07 29.5 0.0 0.037 14.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 AEO63135.1 - 8.4e-07 29.8 0.1 0.012 16.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 AEO63135.1 - 3.5e-06 27.0 0.0 0.0052 16.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 AEO63135.1 - 1.4e-05 25.0 0.0 0.099 12.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.7 AEO63135.1 - 1.5e-05 24.7 0.2 0.16 11.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Miro PF08477.8 AEO63135.1 - 1.5e-05 25.4 0.0 0.048 14.1 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA PF00004.24 AEO63135.1 - 2.7e-05 24.3 0.0 0.3 11.2 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AEO63135.1 - 4.5e-05 23.5 1.7 0.25 11.3 0.1 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 AEO63135.1 - 6.1e-05 22.5 0.0 0.26 10.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 AEO63135.1 - 0.00012 21.8 0.1 0.43 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AEO63135.1 - 0.00013 21.9 0.2 0.35 10.7 0.1 3.5 4 0 0 4 4 4 1 AAA domain Arch_ATPase PF01637.13 AEO63135.1 - 0.00022 21.0 0.2 0.22 11.2 0.0 3.0 3 0 0 3 3 3 1 Archaeal ATPase RNA_helicase PF00910.17 AEO63135.1 - 0.00029 20.9 1.5 1.4 9.1 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA_15 PF13175.1 AEO63135.1 - 0.00047 19.3 0.0 0.18 10.7 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 AEO63135.1 - 0.00062 19.6 0.0 1.6 8.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 AEO63135.1 - 0.00065 19.2 0.8 1 8.7 0.1 3.0 3 0 0 3 3 3 2 AAA-like domain NB-ARC PF00931.17 AEO63135.1 - 0.0051 15.7 0.0 1.2 7.9 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain DUF2813 PF11398.3 AEO63135.1 - 0.0057 15.7 1.4 0.86 8.6 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2813) MobB PF03205.9 AEO63135.1 - 0.007 16.0 0.1 0.37 10.4 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 AEO63135.1 - 0.01 15.6 0.8 6.1 6.6 0.0 3.9 3 1 1 4 4 3 0 Dynamin family UvsY PF11056.3 AEO63135.1 - 0.017 15.2 0.4 0.094 12.8 0.7 1.9 2 0 0 2 2 1 0 Recombination, repair and ssDNA binding protein UvsY SbcCD_C PF13558.1 AEO63135.1 - 0.023 14.6 0.5 1.1 9.2 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DAP3 PF10236.4 AEO63135.1 - 0.028 13.3 1.3 2.7 6.8 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ATP-synt_ab PF00006.20 AEO63135.1 - 0.04 13.4 0.0 0.35 10.3 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FeoB_N PF02421.13 AEO63135.1 - 0.042 13.1 0.1 12 5.1 0.0 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B DUF815 PF05673.8 AEO63135.1 - 0.064 12.1 0.1 2.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 AEO63135.1 - 0.066 12.9 0.2 9.1 5.9 0.1 2.6 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 AEO63135.1 - 0.071 12.5 0.5 6.9 6.1 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.4 AEO63135.1 - 0.076 11.5 0.0 17 3.8 0.0 3.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF87 PF01935.12 AEO63135.1 - 0.083 12.6 1.2 12 5.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 MCM PF00493.18 AEO63135.1 - 0.2 10.4 2.0 11 4.7 0.0 2.7 3 0 0 3 3 3 0 MCM2/3/5 family SNF2_N PF00176.18 AEO63136.1 - 3.1e-71 239.6 1.7 5.1e-71 238.9 1.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 AEO63136.1 - 1.6e-51 174.0 17.1 1.6e-51 174.0 11.9 4.5 3 1 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 AEO63136.1 - 5.5e-16 58.1 0.0 1.4e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IncA PF04156.9 AEO63137.1 - 0.72 9.4 9.8 0.17 11.4 4.6 1.7 1 1 1 2 2 2 0 IncA protein CoA_binding_3 PF13727.1 AEO63137.1 - 1.2 8.9 7.5 1.9 8.2 5.2 1.3 1 0 0 1 1 1 0 CoA-binding domain DEC-1_N PF04625.8 AEO63137.1 - 2.2 6.8 12.2 2.7 6.5 8.4 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region GFO_IDH_MocA PF01408.17 AEO63138.1 - 3e-26 92.2 0.1 5e-26 91.5 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 AEO63138.1 - 6.2e-13 48.5 0.0 1.5e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 AEO63138.1 - 2.4e-05 24.6 0.0 4.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 AEO63138.1 - 0.00041 20.7 0.2 0.0013 19.0 0.0 1.9 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 AEO63138.1 - 0.049 12.6 0.1 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase CoA_binding_2 PF13380.1 AEO63138.1 - 0.059 13.5 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 CoA binding domain AAA_33 PF13671.1 AEO63138.1 - 0.11 12.3 0.1 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Acetyltransf_4 PF13420.1 AEO63139.1 - 1.1e-18 67.6 0.0 1.3e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO63139.1 - 1.1e-09 38.1 0.2 2.6e-09 36.9 0.1 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AEO63139.1 - 1.3e-07 31.7 0.0 1.7e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AEO63139.1 - 3.1e-07 30.6 0.0 3.6e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO63139.1 - 9.9e-05 22.0 0.0 0.00025 20.7 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.1 AEO63139.1 - 0.00019 21.3 0.0 0.00036 20.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO63139.1 - 0.0029 17.7 0.1 0.0083 16.2 0.1 1.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AEO63139.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 AEO63139.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans PF04082.13 AEO63141.1 - 1.7e-13 50.0 0.0 2.9e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 AEO63142.1 - 9.2e-42 143.0 38.5 9.2e-42 143.0 26.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO63142.1 - 1e-07 30.9 27.2 3.3e-07 29.2 18.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 AEO63142.1 - 0.017 13.2 8.6 0.017 13.2 4.9 1.8 1 1 0 1 1 1 0 Transmembrane secretion effector VirB8 PF04335.8 AEO63142.1 - 0.046 13.3 0.8 0.067 12.7 0.0 1.6 2 0 0 2 2 2 0 VirB8 protein Glyco_hydro_72 PF03198.9 AEO63143.1 - 4.8e-128 426.5 3.6 6.1e-128 426.2 2.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 AEO63143.1 - 1.7e-20 73.2 4.8 4.2e-20 72.0 3.3 1.7 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 AEO63143.1 - 2.9e-08 32.9 0.1 4.6e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF247 PF03140.10 AEO63143.1 - 0.0095 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Plant protein of unknown function DUF515 PF04415.7 AEO63143.1 - 6.6 4.8 6.1 10 4.2 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Lipoxygenase PF00305.14 AEO63144.1 - 1.3e-51 175.4 0.1 2.7e-50 171.1 0.0 2.0 2 0 0 2 2 2 2 Lipoxygenase Glyco_hydro_7 PF00840.15 AEO63146.1 - 7.3e-86 288.2 23.0 7.7e-29 100.3 4.6 5.0 1 1 3 4 4 4 4 Glycosyl hydrolase family 7 PTCRA PF15028.1 AEO63147.1 - 0.087 12.3 0.3 0.1 12.1 0.2 1.1 1 0 0 1 1 1 0 Pre-T-cell antigen receptor Peptidase_M20 PF01546.23 AEO63148.1 - 2.2e-08 33.8 0.3 3.1e-08 33.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AEO63148.1 - 1.9e-06 27.6 0.0 7e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain Ytp1 PF10355.4 AEO63149.1 - 7.4e-85 284.4 15.6 1.2e-84 283.7 10.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 AEO63149.1 - 1.4e-30 104.9 1.7 1.4e-30 104.9 1.2 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) GFA PF04828.9 AEO63150.1 - 8.5e-19 67.2 2.1 7.5e-08 32.2 0.2 4.1 2 2 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 AEO63150.1 - 0.15 11.5 0.1 0.15 11.5 0.1 3.8 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain Rpr2 PF04032.11 AEO63150.1 - 1.4 8.8 6.5 1.8 8.5 0.0 3.1 4 0 0 4 4 4 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Jiraiya PF15038.1 AEO63151.1 - 0.021 14.2 0.5 0.086 12.2 0.1 2.1 2 0 0 2 2 2 0 Jiraiya FAD_binding_4 PF01565.18 AEO63152.1 - 7.3e-18 64.3 5.7 9e-18 64.0 2.3 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 AEO63152.1 - 2.7e-05 23.9 1.0 5.6e-05 22.9 0.7 1.6 1 0 0 1 1 1 1 Berberine and berberine like DHquinase_I PF01487.10 AEO63152.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Type I 3-dehydroquinase DUF3328 PF11807.3 AEO63153.1 - 9.7e-26 90.7 0.9 1.3e-25 90.3 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) FAD_binding_4 PF01565.18 AEO63154.1 - 1.6e-25 89.1 7.5 3.5e-25 88.0 5.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO63154.1 - 6.6e-15 54.7 0.0 1.4e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_10 PF00331.15 AEO63155.1 - 2.7e-95 319.0 0.0 3.3e-95 318.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 RAI16-like PF10257.4 AEO63156.1 - 4.6e-78 262.6 0.0 6.8e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein ERbeta_N PF12497.3 AEO63157.1 - 0.01 15.6 0.2 0.016 15.0 0.1 1.3 1 0 0 1 1 1 0 Estrogen receptor beta adh_short PF00106.20 AEO63158.1 - 2.8e-27 95.6 0.9 3.5e-27 95.3 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO63158.1 - 2.3e-19 70.1 0.0 3.2e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO63158.1 - 4.4e-12 46.0 0.2 6.6e-12 45.4 0.1 1.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 AEO63158.1 - 0.0015 17.5 0.0 0.0018 17.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 AEO63158.1 - 0.0093 15.9 0.1 0.012 15.6 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Sugar_tr PF00083.19 AEO63159.1 - 1.1e-95 320.9 19.3 1.3e-95 320.6 13.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO63159.1 - 1.9e-21 76.2 28.2 3.5e-15 55.5 5.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 AEO63159.1 - 0.00012 20.4 8.3 0.00021 19.6 1.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) SGL PF08450.7 AEO63160.1 - 1.5e-31 109.6 0.0 2.4e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 AEO63160.1 - 5.2e-06 26.3 0.0 0.00011 22.1 0.0 2.4 2 0 0 2 2 2 1 Arylesterase NHL PF01436.16 AEO63160.1 - 0.00014 21.6 2.8 0.19 11.7 0.0 3.9 3 0 0 3 3 3 1 NHL repeat Str_synth PF03088.11 AEO63160.1 - 0.00078 19.4 0.0 0.0072 16.3 0.0 2.5 2 1 0 2 2 2 1 Strictosidine synthase Reg_prop PF07494.6 AEO63160.1 - 0.098 12.7 0.9 3.5 7.9 0.0 2.9 2 0 0 2 2 2 0 Two component regulator propeller PQQ_3 PF13570.1 AEO63160.1 - 0.21 11.9 3.3 28 5.1 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain F_bP_aldolase PF01116.15 AEO63161.1 - 6.7e-79 264.9 0.2 7.5e-79 264.8 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.13 AEO63161.1 - 0.047 12.6 0.1 0.079 11.9 0.1 1.3 1 0 0 1 1 1 0 Phosphotriesterase family LacAB_rpiB PF02502.13 AEO63162.1 - 2.9e-43 146.8 0.1 3.4e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.1 AEO63162.1 - 0.029 14.2 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycine-rich SFCGS Fungal_trans_2 PF11951.3 AEO63163.1 - 3.3e-08 32.5 1.3 4.1e-05 22.3 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Dak1 PF02733.12 AEO63164.1 - 8.9e-108 359.7 0.0 1.2e-107 359.2 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 AEO63164.1 - 1.3e-27 96.6 1.3 5.9e-24 84.6 0.1 2.5 1 1 1 2 2 2 2 DAK2 domain Lipase_3 PF01764.20 AEO63165.1 - 1.7e-18 66.5 0.0 3.3e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase2 PF12740.2 AEO63165.1 - 0.013 14.4 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2974 PF11187.3 AEO63165.1 - 0.035 13.4 0.1 3.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 AEO63165.1 - 0.094 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF89 PF01937.14 AEO63166.1 - 3.5e-125 417.4 0.0 4e-125 417.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 zf-C3HC4 PF00097.20 AEO63168.1 - 0.053 13.1 0.6 0.053 13.1 0.4 2.9 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 AEO63171.1 - 2.3e-15 55.9 3.1 3.5e-11 42.5 1.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 AEO63171.1 - 3.2e-11 42.2 10.1 0.00025 20.6 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 AEO63171.1 - 9e-10 37.7 3.5 0.0096 15.5 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 AEO63171.1 - 2.4e-06 28.0 4.2 2.4e-06 28.0 2.9 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 AEO63171.1 - 4.5e-06 26.5 10.0 9.3e-06 25.5 0.7 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO63171.1 - 2.4e-05 23.7 0.3 1.4 8.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 AEO63171.1 - 2.8e-05 23.8 10.5 0.0051 16.6 0.6 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 AEO63171.1 - 0.00012 22.3 1.3 0.00094 19.4 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 AEO63171.1 - 0.00058 20.2 9.5 0.037 14.6 0.2 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 AEO63171.1 - 0.0013 18.8 0.1 0.0027 17.7 0.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 AEO63171.1 - 0.029 14.5 1.6 0.2 11.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO63171.1 - 0.057 13.8 4.6 1.2 9.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 AEO63171.1 - 0.064 13.0 8.0 1.8 8.5 0.1 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 AEO63171.1 - 0.35 11.4 12.1 0.6 10.6 1.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Zn_clus PF00172.13 AEO63173.1 - 0.9 9.5 8.7 2 8.3 6.0 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 AEO63174.1 - 2.1e-28 99.7 0.0 2.8e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 AEO63174.1 - 0.018 13.9 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 CsiD MFS_1 PF07690.11 AEO63175.1 - 3.9e-31 108.0 33.8 3.9e-31 108.0 23.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Acyltransferase PF01553.16 AEO63176.1 - 0.0056 16.1 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase NAD_kinase PF01513.16 AEO63177.1 - 3.9e-47 160.3 0.0 2.7e-46 157.6 0.0 1.9 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 AEO63177.1 - 0.037 13.4 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain CFEM PF05730.6 AEO63178.1 - 4.9e-11 42.2 11.4 7.2e-11 41.7 7.9 1.2 1 0 0 1 1 1 1 CFEM domain Seryl_tRNA_N PF02403.17 AEO63180.1 - 0.067 13.2 30.4 0.12 12.3 7.2 2.9 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Prefoldin_2 PF01920.15 AEO63180.1 - 0.078 12.7 20.4 0.02 14.6 4.6 3.1 3 0 0 3 3 3 0 Prefoldin subunit ATG16 PF08614.6 AEO63180.1 - 0.099 12.4 29.9 0.065 13.0 6.4 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) GAS PF13851.1 AEO63180.1 - 0.98 8.5 28.3 3.2 6.8 7.3 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 AEO63180.1 - 1.7 8.2 28.4 0.88 9.1 15.8 2.8 1 1 1 2 2 2 0 IncA protein Spc7 PF08317.6 AEO63180.1 - 2.6 6.6 28.3 1.6 7.3 7.3 2.4 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4200 PF13863.1 AEO63180.1 - 5.9 6.8 36.5 1.2 9.1 10.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Conotoxin PF02950.12 AEO63181.1 - 0.041 14.6 0.1 0.054 14.2 0.1 1.2 1 0 0 1 1 1 0 Conotoxin DEC-1_N PF04625.8 AEO63181.1 - 0.61 8.7 6.6 0.64 8.6 4.6 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Ribosomal_60s PF00428.14 AEO63181.1 - 4 7.9 11.5 5.2 7.5 8.0 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein 4HBT_2 PF13279.1 AEO63182.1 - 3.1e-20 72.8 0.2 5e-20 72.1 0.1 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 AEO63182.1 - 0.0041 17.2 0.1 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 Thioesterase superfamily DUF2782 PF11191.3 AEO63182.1 - 0.085 12.8 0.1 10 6.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2782) Complex1_LYR_2 PF13233.1 AEO63183.1 - 9.1e-05 22.8 0.0 9.8e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 AEO63183.1 - 0.0032 17.2 0.1 0.0056 16.4 0.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AEO63183.1 - 0.033 14.4 0.1 0.05 13.8 0.1 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Methyltransf_25 PF13649.1 AEO63184.1 - 1.4e-09 38.2 0.0 4.2e-09 36.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO63184.1 - 2.3e-09 37.6 0.0 6.2e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO63184.1 - 1.2e-07 32.2 0.0 2.7e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO63184.1 - 2.4e-07 30.4 0.0 0.0077 15.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 AEO63184.1 - 9e-07 28.7 0.0 2.5e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO63184.1 - 0.0001 22.7 0.0 0.00094 19.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO63184.1 - 0.00012 22.0 0.0 0.00093 19.2 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO63184.1 - 0.00015 21.0 0.0 0.00058 19.0 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Zip PF02535.17 AEO63184.1 - 0.016 14.2 0.4 0.016 14.2 0.3 2.8 2 1 1 3 3 2 0 ZIP Zinc transporter CheR PF01739.13 AEO63184.1 - 0.05 12.8 0.0 0.33 10.2 0.0 2.0 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain DUF3735 PF12537.3 AEO63184.1 - 0.11 12.6 0.1 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) MTS PF05175.9 AEO63184.1 - 0.11 11.8 0.0 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.1 AEO63184.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 AEO63184.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Exo_endo_phos PF03372.18 AEO63185.1 - 4.8e-26 92.2 0.1 7e-26 91.6 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 AEO63185.1 - 6.3e-17 60.7 4.1 6.6e-08 32.0 0.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO63185.1 - 8.3e-16 57.4 14.0 4e-08 32.9 0.9 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 AEO63185.1 - 4e-09 35.2 3.3 0.13 12.3 0.0 4.3 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 AEO63185.1 - 2.7e-06 26.6 5.7 0.31 11.4 0.2 4.1 3 0 0 3 3 3 3 Leucine rich repeat LRR_6 PF13516.1 AEO63185.1 - 0.008 16.1 4.2 0.92 9.7 0.2 4.2 5 0 0 5 5 5 1 Leucine Rich repeat TFIIA PF03153.8 AEO63185.1 - 5.1 6.8 7.8 7.7 6.3 5.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zn_clus PF00172.13 AEO63187.1 - 2.2e-10 40.2 10.2 3.9e-10 39.4 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO63187.1 - 1.6e-09 37.0 1.5 7e-09 34.9 1.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Cerato-platanin PF07249.7 AEO63188.1 - 1.6e-55 186.1 0.9 1.9e-55 185.9 0.6 1.0 1 0 0 1 1 1 1 Cerato-platanin FAD_binding_3 PF01494.14 AEO63190.1 - 4.6e-35 121.3 0.0 1e-34 120.1 0.0 1.5 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.19 AEO63190.1 - 0.00018 20.5 0.5 0.0016 17.4 0.0 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AEO63190.1 - 0.0012 18.9 0.1 0.014 15.5 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO63190.1 - 0.0024 18.2 0.0 0.68 10.3 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO63190.1 - 0.038 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO63190.1 - 0.058 12.2 0.1 0.058 12.2 0.0 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein TrkA_N PF02254.13 AEO63190.1 - 0.082 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 AEO63190.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thioesterase PF00975.15 AEO63191.1 - 4.7e-14 53.1 0.1 5.9e-12 46.3 0.0 2.4 2 1 0 2 2 2 2 Thioesterase domain Abhydrolase_6 PF12697.2 AEO63191.1 - 2.2e-07 30.9 0.0 5.7e-07 29.6 0.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO63191.1 - 0.0097 15.6 0.1 0.019 14.7 0.0 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family ERF PF04404.7 AEO63191.1 - 1.4 8.3 7.6 2.3 7.7 5.3 1.3 1 0 0 1 1 1 0 ERF superfamily DUF898 PF05987.8 AEO63192.1 - 0.022 13.6 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Acyltransferase PF01553.16 AEO63195.1 - 0.0091 15.4 0.0 0.04 13.3 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase DUF3538 PF12057.3 AEO63195.1 - 0.074 12.6 0.0 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3538) DUF3617 PF12276.3 AEO63195.1 - 0.23 10.9 1.2 0.54 9.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) Defensin_propep PF00879.13 AEO63195.1 - 0.99 9.4 8.0 2.5 8.1 5.5 1.7 1 0 0 1 1 1 0 Defensin propeptide ILVD_EDD PF00920.16 AEO63196.1 - 3.3e-210 698.9 0.0 3.8e-210 698.7 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family CLP_protease PF00574.18 AEO63197.1 - 9.5e-67 224.1 0.0 1.2e-66 223.8 0.0 1.1 1 0 0 1 1 1 1 Clp protease Phage_HK97_TLTM PF06120.6 AEO63197.1 - 0.091 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Phage_NinH PF06322.6 AEO63197.1 - 0.14 11.7 0.2 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 Phage NinH protein DNA_primase_lrg PF04104.9 AEO63199.1 - 2.7e-82 275.9 0.0 3.8e-82 275.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DUF508 PF04370.7 AEO63200.1 - 1.5 8.4 6.0 1.8 8.1 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Metallophos PF00149.23 AEO63203.1 - 2.1e-12 46.8 0.3 8.1e-12 44.9 0.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AEO63203.1 - 1.3e-07 31.5 0.0 3.4e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DnaJ PF00226.26 AEO63206.1 - 1.5e-19 69.5 1.7 4.8e-19 67.8 1.1 2.0 1 0 0 1 1 1 1 DnaJ domain MBOAT PF03062.14 AEO63207.1 - 8.8e-35 120.3 10.2 2.2e-34 119.0 7.1 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Pkinase PF00069.20 AEO63208.1 - 4.3e-23 81.7 0.0 1.1e-22 80.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO63208.1 - 7.4e-16 57.9 0.0 1.5e-15 57.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase HSP90 PF00183.13 AEO63209.1 - 3e-258 857.5 30.0 3.5e-258 857.3 20.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 AEO63209.1 - 8e-12 44.8 0.0 1.4e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AEO63209.1 - 1e-11 44.6 0.2 1e-11 44.6 0.2 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.8 AEO63209.1 - 0.072 13.4 0.4 0.072 13.4 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) PVL_ORF50 PF07768.6 AEO63209.1 - 2.8 7.9 16.3 1.6 8.7 4.8 3.1 3 0 0 3 3 3 0 PVL ORF-50-like family FKBP_C PF00254.23 AEO63210.1 - 2.1e-37 127.0 0.0 2.7e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Flavin_Reduct PF01613.13 AEO63211.1 - 3.8e-26 91.7 0.0 7e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Flavin reductase like domain Pyrophosphatase PF00719.14 AEO63212.1 - 0.028 13.8 0.5 0.037 13.4 0.4 1.2 1 0 0 1 1 1 0 Inorganic pyrophosphatase RVT_thumb PF06817.9 AEO63212.1 - 0.054 13.0 0.5 0.077 12.5 0.3 1.2 1 0 0 1 1 1 0 Reverse transcriptase thumb domain DUF3347 PF11827.3 AEO63212.1 - 0.08 12.9 2.4 0.1 12.5 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) FMN_red PF03358.10 AEO63212.1 - 0.2 11.1 1.2 0.51 9.8 0.2 1.9 1 1 1 2 2 2 0 NADPH-dependent FMN reductase APC_CDC26 PF10471.4 AEO63212.1 - 0.24 12.1 4.5 0.32 11.7 2.7 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 TP53IP5 PF15331.1 AEO63212.1 - 0.37 10.6 3.0 0.44 10.4 2.1 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Spore_coat_CotO PF14153.1 AEO63212.1 - 0.69 9.3 4.4 0.8 9.1 3.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO MSP1_C PF07462.6 AEO63212.1 - 0.8 8.0 5.0 0.88 7.8 3.5 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Med3 PF11593.3 AEO63212.1 - 1.2 8.2 5.6 1.4 8.0 3.9 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1075 PF06388.6 AEO63212.1 - 3.6 7.2 6.4 5.2 6.7 0.7 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1075) Rtf2 PF04641.7 AEO63212.1 - 4.2 6.4 7.3 5 6.2 5.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Pkinase PF00069.20 AEO63213.1 - 2.6e-21 75.9 0.0 7.6e-21 74.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO63213.1 - 2.1e-15 56.5 0.0 1.6e-09 37.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase PSI_PSAK PF01241.13 AEO63213.1 - 0.09 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Photosystem I psaG / psaK Kinase-like PF14531.1 AEO63213.1 - 0.14 11.1 0.0 2.7 6.8 0.0 2.1 1 1 0 1 1 1 0 Kinase-like Ribosomal_L31 PF01197.13 AEO63214.1 - 0.015 15.2 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L31 RNase_H2_suC PF08615.6 AEO63214.1 - 0.036 13.9 0.2 0.044 13.6 0.2 1.2 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Vps5 PF09325.5 AEO63215.1 - 1.8e-87 292.5 6.8 3e-87 291.7 4.7 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 AEO63215.1 - 3.7e-25 87.9 0.0 7.9e-25 86.8 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_2 PF10455.4 AEO63215.1 - 0.028 13.3 5.7 0.065 12.1 3.9 1.5 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking ORC4_C PF14629.1 AEO63215.1 - 0.056 12.8 0.3 0.14 11.5 0.2 1.6 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus DUF3439 PF11921.3 AEO63215.1 - 4.7 6.9 10.9 10 5.9 7.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) WD40 PF00400.27 AEO63216.1 - 7e-51 168.3 20.7 7.7e-09 35.1 0.5 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 AEO63216.1 - 2.6e-45 153.9 0.1 4e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 AEO63216.1 - 3.9e-07 29.6 0.0 1e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 AEO63216.1 - 1.2e-06 28.3 0.1 8.6e-05 22.3 0.0 3.1 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 AEO63216.1 - 0.0062 15.3 0.0 1.1 7.9 0.0 2.8 2 2 0 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 AEO63216.1 - 0.02 13.0 2.2 8.9 4.3 0.0 3.5 2 1 2 4 4 4 0 Nucleoporin Nup120/160 IKI3 PF04762.7 AEO63216.1 - 0.12 10.2 0.1 0.37 8.5 0.1 1.7 2 0 0 2 2 2 0 IKI3 family Med11 PF10280.4 AEO63217.1 - 1.8e-23 82.8 0.0 2.3e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein Peptidase_M28 PF04389.12 AEO63218.1 - 1.9e-31 109.1 0.0 3.3e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 AEO63218.1 - 0.0089 15.5 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 zf-CCHC PF00098.18 AEO63219.1 - 1.2e-11 43.9 9.7 1.4e-05 24.7 0.4 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 AEO63219.1 - 4.7e-09 35.7 0.2 9.5e-09 34.7 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 AEO63219.1 - 1.6e-06 27.7 5.3 0.0012 18.5 2.0 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 AEO63219.1 - 5.3e-06 25.9 0.2 1.4e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 AEO63219.1 - 0.00057 19.4 6.5 0.18 11.4 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 AEO63219.1 - 0.0036 16.9 8.2 0.26 10.9 0.4 2.8 1 1 1 2 2 2 2 Zinc knuckle Peptidase_M16_C PF05193.16 AEO63219.1 - 2.9 7.5 4.2 6.5 6.3 0.2 2.9 2 1 0 2 2 2 0 Peptidase M16 inactive domain GST_N_3 PF13417.1 AEO63220.1 - 3.2e-14 52.9 0.0 6.1e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO63220.1 - 6e-13 48.4 0.3 1.2e-12 47.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AEO63220.1 - 1.6e-12 47.2 0.0 3.6e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AEO63220.1 - 2.7e-11 43.4 0.0 7.5e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO63220.1 - 1.2e-10 41.1 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 AEO63220.1 - 2.8e-10 40.5 0.1 5.1e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Metallophos PF00149.23 AEO63221.1 - 1.5e-14 53.8 0.3 4.1e-14 52.4 0.2 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AEO63221.1 - 0.00018 21.4 0.1 0.00038 20.3 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Methyltransf_11 PF08241.7 AEO63222.1 - 0.039 14.4 0.0 0.088 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SAP PF02037.22 AEO63223.1 - 4.4e-15 54.7 0.0 8.2e-15 53.9 0.0 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 AEO63223.1 - 0.0034 16.9 0.1 0.0083 15.6 0.0 1.7 1 0 0 1 1 1 1 HeH/LEM domain Armet PF10208.4 AEO63223.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Imm37 PF15598.1 AEO63226.1 - 0.025 14.4 0.7 0.045 13.6 0.5 1.4 1 0 0 1 1 1 0 Immunity protein 37 BTV_NS2 PF04514.7 AEO63228.1 - 0.025 13.4 6.8 0.052 12.4 4.7 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 MIP-T3 PF10243.4 AEO63228.1 - 5.6 5.3 28.0 8.5 4.7 19.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2217 PF10265.4 AEO63228.1 - 7.2 5.2 8.7 10 4.7 6.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SPRY PF00622.23 AEO63229.1 - 7e-18 64.9 0.0 1.1e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Zn_clus PF00172.13 AEO63230.1 - 1.5e-08 34.4 11.4 2.3e-08 33.8 7.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO63230.1 - 2.3e-08 33.0 1.3 2.5e-08 32.9 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain HEAT_EZ PF13513.1 AEO63232.1 - 5e-27 93.6 13.8 1.1e-14 54.4 0.0 11.4 10 3 6 16 16 15 3 HEAT-like repeat HEAT PF02985.17 AEO63232.1 - 8.2e-24 81.5 16.0 2.5e-05 23.9 0.0 10.1 12 0 0 12 12 12 5 HEAT repeat HEAT_2 PF13646.1 AEO63232.1 - 1.2e-22 79.9 0.5 1.5e-06 28.3 0.0 7.9 4 3 7 11 11 11 8 HEAT repeats MMS19_C PF12460.3 AEO63232.1 - 6.3e-11 41.6 1.9 0.0038 16.0 0.0 5.1 4 1 1 5 5 5 3 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.2 AEO63232.1 - 1.9e-09 37.7 0.0 0.11 12.9 0.0 7.2 6 2 2 8 8 8 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 AEO63232.1 - 4.5e-06 26.2 0.1 0.093 12.5 0.0 5.9 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 AEO63232.1 - 7.7e-05 22.5 1.0 0.002 17.9 0.2 3.7 3 1 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 AEO63232.1 - 0.00042 19.7 0.3 35 3.6 0.0 6.3 5 2 1 6 6 6 0 CLASP N terminal RIX1 PF08167.7 AEO63232.1 - 0.028 14.0 0.1 7.3 6.2 0.0 4.2 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis Xpo1 PF08389.7 AEO63232.1 - 0.074 12.9 1.9 12 5.7 0.0 4.3 5 0 0 5 5 5 0 Exportin 1-like protein DUF3437 PF11919.3 AEO63232.1 - 0.089 12.5 0.0 0.98 9.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) HEAT_PBS PF03130.11 AEO63232.1 - 0.26 11.8 7.5 2.9 8.6 0.0 5.4 7 0 0 7 7 3 0 PBS lyase HEAT-like repeat N2227 PF07942.7 AEO63234.1 - 2e-99 331.9 0.0 2.5e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 AEO63234.1 - 2.3e-08 33.9 0.0 4.1e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO63234.1 - 0.0012 19.3 0.0 0.0054 17.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO63234.1 - 0.0032 17.9 0.0 0.006 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO63234.1 - 0.094 12.3 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain HsdM_N PF12161.3 AEO63234.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 HsdM N-terminal domain Methyltransf_18 PF12847.2 AEO63234.1 - 0.13 12.8 0.0 0.72 10.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 AEO63235.1 - 3.5e-25 88.8 7.8 5.4e-25 88.2 5.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO63235.1 - 6.8e-21 75.1 0.0 9.5e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO63235.1 - 3.1e-15 56.2 3.7 4.7e-15 55.7 2.6 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 AEO63235.1 - 0.023 14.4 1.1 0.13 12.0 0.2 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase malic PF00390.14 AEO63235.1 - 0.092 12.3 0.1 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain DUF2407 PF10302.4 AEO63236.1 - 4.4e-06 26.7 0.0 9.7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 AEO63236.1 - 2.3e-05 23.6 0.0 4.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family PS_Dcarbxylase PF02666.10 AEO63237.1 - 9.6e-81 269.9 0.0 2.8e-80 268.4 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.6 AEO63237.1 - 0.13 11.8 0.7 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 MNLL subunit Nitroreductase PF00881.19 AEO63238.1 - 3e-14 53.1 0.0 3.6e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DUF1983 PF09327.6 AEO63238.1 - 0.089 12.7 0.3 0.74 9.8 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1983) FAD_binding_1 PF00667.15 AEO63239.1 - 9.3e-44 149.4 0.0 1.3e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 AEO63239.1 - 2.1e-10 41.1 0.0 6.6e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain PemK PF02452.12 AEO63240.1 - 0.045 13.9 0.1 0.084 13.0 0.1 1.4 1 0 0 1 1 1 0 PemK-like protein DUF4558 PF15104.1 AEO63241.1 - 0.44 10.5 4.8 0.33 10.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) zf-rbx1 PF12678.2 AEO63243.1 - 1.1e-12 47.8 1.5 2e-12 47.0 1.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 AEO63243.1 - 1.3e-11 44.1 4.6 2.2e-11 43.3 3.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AEO63243.1 - 2e-07 30.5 4.1 6.8e-07 28.8 3.0 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO63243.1 - 7.3e-06 25.9 3.1 2e-05 24.5 2.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO63243.1 - 7.3e-06 25.6 2.8 1.3e-05 24.7 2.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AEO63243.1 - 8.7e-06 25.3 3.5 1.5e-05 24.5 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AEO63243.1 - 0.00013 21.7 0.7 0.00024 20.9 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 AEO63243.1 - 0.0029 17.2 2.3 0.0094 15.6 1.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 AEO63243.1 - 0.015 14.8 0.2 0.029 13.9 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 AEO63243.1 - 0.35 10.4 2.3 0.79 9.3 1.6 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 AEO63243.1 - 1.5 8.8 5.4 1.3 8.9 2.2 2.1 2 1 0 2 2 2 0 FANCL C-terminal domain Methyltransf_16 PF10294.4 AEO63245.1 - 8.1e-07 28.6 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase zf-C2H2 PF00096.21 AEO63246.1 - 0.00021 21.4 19.6 0.99 9.8 0.5 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO63246.1 - 0.00049 20.2 16.3 0.13 12.6 0.0 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AEO63246.1 - 0.0069 16.2 1.3 0.072 13.0 0.7 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger DUF629 PF04780.7 AEO63246.1 - 0.14 10.6 0.2 0.41 9.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Fibrillarin PF01269.12 AEO63247.1 - 3.1e-106 353.4 0.0 3.9e-106 353.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 AEO63247.1 - 2.9e-06 26.9 0.0 4.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 AEO63247.1 - 0.004 16.7 0.1 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 AEO63247.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF4159 PF13709.1 AEO63247.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Ribosomal_L22 PF00237.14 AEO63248.1 - 8.5e-34 115.6 0.1 1.2e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Peptidase_C12 PF01088.16 AEO63249.1 - 1.1e-69 233.8 0.0 1.6e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Xan_ur_permease PF00860.15 AEO63250.1 - 3e-27 95.1 30.5 1.1e-25 89.9 19.9 3.2 2 1 0 2 2 2 1 Permease family Dicty_CAR PF05462.6 AEO63252.1 - 5.8e-13 48.4 7.7 5.8e-13 48.4 5.4 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 AEO63252.1 - 3.3e-12 45.9 3.8 5.8e-12 45.2 2.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.16 AEO63252.1 - 2.3e-08 33.4 0.0 3.3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 AEO63252.1 - 1.4e-07 31.2 9.3 2.6e-07 30.4 6.5 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 STE3 PF02076.10 AEO63252.1 - 0.0033 16.5 5.1 0.0069 15.5 3.5 1.5 1 0 0 1 1 1 1 Pheromone A receptor Vps39_2 PF10367.4 AEO63253.1 - 2.5e-06 27.6 0.0 5.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 DUF605 PF04652.11 AEO63253.1 - 0.031 13.6 8.6 0.055 12.8 5.9 1.3 1 0 0 1 1 1 0 Vta1 like Vps39_1 PF10366.4 AEO63253.1 - 0.075 13.0 0.0 0.74 9.8 0.0 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 adh_short PF00106.20 AEO63254.1 - 1e-21 77.5 5.7 2e-21 76.6 4.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO63254.1 - 1.6e-12 47.4 2.1 1.6e-12 47.4 1.5 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 AEO63254.1 - 1.9e-08 34.0 0.0 3.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 AEO63254.1 - 1.4e-05 25.0 0.0 2.3e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 AEO63254.1 - 0.00016 20.7 0.0 0.00022 20.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 AEO63254.1 - 0.024 14.4 0.3 0.058 13.1 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 AEO63254.1 - 0.046 13.7 3.9 0.62 10.0 2.7 2.4 1 1 0 1 1 1 0 NADH(P)-binding CASP_C PF08172.7 AEO63255.1 - 2e-88 295.6 0.0 2e-88 295.6 0.0 3.2 3 1 0 3 3 3 1 CASP C terminal Cast PF10174.4 AEO63255.1 - 0.001 17.2 6.2 0.001 17.2 4.3 3.1 3 0 0 3 3 3 2 RIM-binding protein of the cytomatrix active zone ATG16 PF08614.6 AEO63255.1 - 0.012 15.4 50.1 0.99 9.1 5.6 4.6 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) bZIP_2 PF07716.10 AEO63255.1 - 0.013 15.3 5.1 0.013 15.3 3.5 7.8 7 1 0 7 7 7 0 Basic region leucine zipper CENP-F_leu_zip PF10473.4 AEO63255.1 - 0.015 15.1 3.1 0.015 15.1 2.1 5.7 3 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.14 AEO63255.1 - 0.026 14.0 0.0 0.026 14.0 0.0 4.4 3 1 1 5 5 5 0 Ezrin/radixin/moesin family UPF0184 PF03670.8 AEO63255.1 - 0.31 11.2 0.1 0.31 11.2 0.1 3.8 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0184) IncA PF04156.9 AEO63255.1 - 0.78 9.3 61.5 0.058 12.9 3.7 5.4 3 1 1 5 5 5 0 IncA protein DUF3584 PF12128.3 AEO63255.1 - 2.4 5.3 51.3 1.1 6.4 6.5 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3584) Tropomyosin_1 PF12718.2 AEO63255.1 - 3.1 7.6 54.4 4.7 7.0 4.8 5.3 3 1 2 5 5 5 0 Tropomyosin like Reo_sigmaC PF04582.7 AEO63255.1 - 5.5 6.0 23.8 0.54 9.3 1.8 4.8 3 1 2 5 5 5 0 Reovirus sigma C capsid protein DUF3455 PF11937.3 AEO63256.1 - 2.5e-39 135.0 0.1 4.2e-39 134.3 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3455) NIF PF03031.13 AEO63257.1 - 8.3e-18 64.5 0.0 1.1e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase EF1G PF00647.14 AEO63258.1 - 3.4e-43 145.6 0.0 6e-43 144.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 AEO63258.1 - 2.8e-15 56.0 0.0 1.3e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 AEO63258.1 - 3.7e-12 45.9 0.0 2.7e-11 43.2 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AEO63258.1 - 1.5e-11 44.2 0.1 8.4e-11 41.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 AEO63258.1 - 8.2e-09 35.5 0.0 2.3e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 AEO63258.1 - 1.1e-06 29.0 0.0 2.6e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 AEO63258.1 - 0.00017 21.5 0.0 0.00048 20.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PTS_IIA PF02255.11 AEO63258.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit Ribosomal_S9 PF00380.14 AEO63259.1 - 4.3e-37 127.0 0.9 9e-37 126.0 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF-hand_1 PF00036.27 AEO63261.1 - 2.4e-26 88.9 11.7 8.7e-07 27.8 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 AEO63261.1 - 4.1e-23 81.2 3.1 5.5e-12 45.6 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AEO63261.1 - 8e-20 68.8 5.4 4.7e-05 22.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 AEO63261.1 - 8.3e-19 66.0 11.7 2.9e-06 26.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 AEO63261.1 - 1.5e-15 56.4 12.0 1.5e-05 24.4 0.6 4.5 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 AEO63261.1 - 5.5e-07 29.6 0.0 0.00057 19.9 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 AEO63261.1 - 1.6e-06 27.7 7.7 0.0014 18.3 0.4 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 AEO63261.1 - 0.046 13.6 0.1 1.1 9.2 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain EPL1 PF10513.4 AEO63262.1 - 2.3e-30 105.9 0.4 2.3e-30 105.9 0.3 3.3 3 1 0 3 3 3 1 Enhancer of polycomb-like DUF641 PF04859.7 AEO63262.1 - 0.0099 15.6 4.6 0.24 11.1 0.0 2.5 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) adh_short PF00106.20 AEO63262.1 - 0.17 11.7 0.1 6.8 6.5 0.0 2.6 2 0 0 2 2 2 0 short chain dehydrogenase Trypan_PARP PF05887.6 AEO63262.1 - 0.21 11.4 26.3 0.47 10.2 18.2 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Peptidase_M22 PF00814.20 AEO63263.1 - 2.4e-83 279.7 0.1 2.9e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Staygreen PF12638.2 AEO63263.1 - 0.11 11.9 0.0 0.77 9.2 0.0 2.0 2 0 0 2 2 2 0 Staygreen protein AMPKBI PF04739.10 AEO63264.1 - 1.6e-31 108.1 2.7 4.7e-31 106.6 1.9 1.8 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain Spt4 PF06093.8 AEO63265.1 - 1.1e-32 111.6 0.1 1.4e-32 111.3 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Kin17_mid PF10357.4 AEO63266.1 - 1.3e-48 163.7 1.9 2.8e-48 162.7 1.3 1.6 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 AEO63266.1 - 4e-05 23.6 4.9 6.7e-05 22.9 3.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AEO63266.1 - 0.00032 20.7 5.6 0.0006 19.8 3.9 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 AEO63266.1 - 0.001 19.1 1.4 0.001 19.1 1.0 1.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Methyltransf_7 PF03492.10 AEO63266.1 - 0.029 13.1 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase AA_kinase PF00696.23 AEO63267.1 - 2.7e-37 128.6 0.1 4.1e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 AEO63267.1 - 1.4e-16 59.6 1.0 2.1e-10 39.8 0.0 2.6 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 AEO63267.1 - 1.7e-14 53.0 4.9 1.5e-10 40.4 0.1 2.4 2 0 0 2 2 2 2 ACT domain ABC_membrane PF00664.18 AEO63268.1 - 1.9e-46 158.7 11.0 2.4e-46 158.3 7.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 AEO63268.1 - 2.8e-34 118.3 0.0 7.2e-34 117.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 AEO63268.1 - 6e-06 25.6 0.0 0.00028 20.1 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AEO63268.1 - 0.00011 22.3 0.2 0.65 9.9 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 AEO63268.1 - 0.00014 21.9 0.0 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 AEO63268.1 - 0.0021 18.8 0.0 0.0053 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 AEO63268.1 - 0.0033 16.9 0.0 0.0096 15.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 AEO63268.1 - 0.0041 17.3 0.1 0.058 13.5 0.1 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO63268.1 - 0.0058 16.7 0.1 0.03 14.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 AEO63268.1 - 0.018 13.6 0.7 0.029 12.9 0.1 1.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_5 PF07728.9 AEO63268.1 - 0.018 14.7 0.1 0.055 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 AEO63268.1 - 0.04 13.8 1.3 0.33 10.9 0.9 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 AEO63268.1 - 0.05 13.0 0.4 0.21 10.9 0.3 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 AEO63268.1 - 0.051 12.9 0.2 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.1 AEO63268.1 - 0.057 13.7 0.5 0.15 12.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.1 AEO63268.1 - 0.088 12.8 0.0 0.95 9.5 0.0 2.5 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_10 PF12846.2 AEO63268.1 - 0.094 12.1 0.7 0.42 9.9 0.2 2.0 2 0 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 AEO63268.1 - 0.21 10.7 0.0 0.55 9.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CTD_bind PF04818.8 AEO63269.1 - 2.9e-21 75.4 0.1 7.4e-21 74.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DrrA_P4M PF14860.1 AEO63269.1 - 0.059 13.1 2.3 5.7 6.7 0.0 3.1 2 1 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain CTK3 PF12243.3 AEO63269.1 - 0.1 12.2 1.6 0.14 11.8 0.1 1.9 3 0 0 3 3 3 0 CTD kinase subunit gamma CTK3 Clathrin_lg_ch PF01086.12 AEO63270.1 - 7e-74 248.5 2.7 7.8e-74 248.3 1.8 1.0 1 0 0 1 1 1 1 Clathrin light chain HisK_N PF09385.5 AEO63270.1 - 0.07 12.7 0.9 0.13 11.9 0.7 1.4 1 0 0 1 1 1 0 Histidine kinase N terminal ATP-synt_B PF00430.13 AEO63270.1 - 1.3 8.8 9.7 2.6 7.8 6.7 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) COX7a PF02238.10 AEO63271.1 - 0.0021 17.7 0.5 0.0053 16.4 0.3 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIa SNARE PF05739.14 AEO63272.1 - 4.4e-20 71.1 3.2 4.4e-20 71.1 2.2 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 AEO63272.1 - 1.5e-15 57.1 6.5 4.5e-14 52.4 0.1 2.5 2 1 0 2 2 2 2 Syntaxin MCPsignal PF00015.16 AEO63272.1 - 0.013 15.0 8.8 0.057 12.9 0.7 2.5 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.1 AEO63272.1 - 0.018 15.0 9.0 0.73 9.8 1.0 3.1 2 1 1 3 3 3 0 Syntaxin-like protein Use1 PF09753.4 AEO63272.1 - 0.15 11.4 7.1 0.29 10.5 4.9 1.6 1 1 0 1 1 1 0 Membrane fusion protein Use1 SlyX PF04102.7 AEO63272.1 - 1.8 9.0 6.3 2.5 8.5 0.6 3.3 3 1 1 4 4 4 0 SlyX DNA_repr_REX1B PF14966.1 AEO63272.1 - 7 7.0 7.0 0.47 10.8 0.2 2.6 3 1 0 3 3 3 0 DNA repair REX1-B EF-hand_1 PF00036.27 AEO63273.1 - 2.8e-41 135.6 12.8 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 AEO63273.1 - 1.7e-36 124.1 5.8 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 AEO63273.1 - 8.5e-35 118.1 12.2 6.8e-16 57.6 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 AEO63273.1 - 1.2e-30 102.6 8.0 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 AEO63273.1 - 5.2e-26 88.7 9.7 1.4e-06 27.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 AEO63273.1 - 1.3e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 AEO63273.1 - 2.6e-09 36.7 1.9 0.00056 19.6 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 AEO63273.1 - 1.5e-08 34.6 0.1 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 AEO63273.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 AEO63273.1 - 4.4e-07 29.7 2.1 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 AEO63273.1 - 0.00014 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 AEO63273.1 - 0.00023 20.7 0.2 0.075 12.5 0.0 2.7 1 1 1 3 3 3 1 Caleosin related protein Tenui_NCP PF04876.7 AEO63273.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 AEO63273.1 - 0.0026 17.7 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 AEO63273.1 - 0.0083 16.4 1.3 2.5 8.4 0.0 2.5 1 1 2 3 3 3 2 Toprim-like DUF3349 PF11829.3 AEO63273.1 - 0.021 15.2 0.4 12 6.4 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 AEO63273.1 - 0.14 11.8 2.5 0.83 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 AEO63273.1 - 0.38 10.3 4.1 0.99 9.0 1.1 2.2 1 1 0 2 2 2 0 RloB-like protein PB1 PF00564.19 AEO63273.1 - 0.45 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain Adaptin_N PF01602.15 AEO63274.1 - 3.9e-141 470.9 1.4 4.7e-141 470.6 1.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 AEO63274.1 - 6.5e-19 68.3 0.0 1.6e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 AEO63274.1 - 1.9e-06 28.0 1.0 0.096 12.9 0.0 4.6 3 3 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 AEO63274.1 - 3.7e-05 23.6 3.1 0.00062 19.6 0.2 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 AEO63274.1 - 0.0011 18.8 1.5 13 6.1 0.0 5.2 4 1 1 5 5 5 1 HEAT repeat TIP120 PF08623.5 AEO63274.1 - 0.018 14.6 0.5 0.059 12.9 0.0 2.1 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Arm PF00514.18 AEO63274.1 - 0.021 14.6 0.0 44 4.0 0.0 4.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 AEO63274.1 - 0.031 13.9 0.0 0.41 10.3 0.0 2.6 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis G-patch_2 PF12656.2 AEO63274.1 - 0.06 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 DExH-box splicing factor binding site DUF947 PF06102.7 AEO63275.1 - 7.6e-57 191.7 19.2 1.2e-56 191.1 13.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF947) DUF4080 PF13311.1 AEO63275.1 - 5.7 6.9 6.9 11 5.9 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) ABC1 PF03109.11 AEO63276.1 - 3.2e-32 110.9 0.0 7.4e-32 109.8 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Es2 PF09751.4 AEO63277.1 - 2.7e-97 326.8 0.3 4.6e-96 322.7 0.2 2.0 1 1 0 1 1 1 1 Nuclear protein Es2 zf-RING_2 PF13639.1 AEO63278.1 - 3.3e-09 36.4 3.3 3.3e-09 36.4 2.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 AEO63278.1 - 4.8e-07 29.3 1.1 4.8e-07 29.3 0.8 2.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO63278.1 - 1.7e-05 24.4 1.0 4.5e-05 23.0 0.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 AEO63278.1 - 2.5e-05 24.3 1.0 6.5e-05 22.9 0.5 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AEO63278.1 - 5.5e-05 23.1 6.9 0.0001 22.2 0.6 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO63278.1 - 8.9e-05 22.0 4.6 8.9e-05 22.0 3.2 2.9 2 1 2 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AEO63278.1 - 0.025 14.4 0.8 0.025 14.4 0.5 2.6 3 0 0 3 3 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 AEO63278.1 - 0.066 12.9 4.0 0.15 11.8 0.6 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 AEO63278.1 - 0.14 12.0 4.0 0.73 9.7 2.8 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 AEO63278.1 - 0.18 11.4 2.8 0.61 9.7 0.3 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-FPG_IleRS PF06827.9 AEO63278.1 - 0.52 10.0 4.1 4.3 7.0 0.2 3.1 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS zf-RING_UBOX PF13445.1 AEO63278.1 - 8.1 6.2 8.0 0.94 9.2 0.6 2.5 2 1 0 2 2 2 0 RING-type zinc-finger Hus1 PF04005.7 AEO63279.1 - 1.6e-73 247.2 0.0 2e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Sec16_C PF12931.2 AEO63280.1 - 1.5e-96 323.4 0.0 2.1e-96 323.0 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 AEO63280.1 - 2.4e-31 108.1 0.0 4.4e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Hydrolase PF00702.21 AEO63281.1 - 1.2e-17 65.0 0.0 3.2e-17 63.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 AEO63281.1 - 5.3e-16 58.3 0.0 1.4e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 AEO63281.1 - 2e-10 41.1 0.0 5.3e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO63281.1 - 9.4e-05 22.2 0.0 0.00032 20.5 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AEO63281.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Suc_Fer-like PF06999.7 AEO63282.1 - 9.2e-56 189.4 0.0 1.1e-55 189.1 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Methyltransf_26 PF13659.1 AEO63283.1 - 8.6e-14 51.5 0.1 2.7e-13 49.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO63283.1 - 1.1e-07 31.5 0.0 1.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO63283.1 - 6.6e-06 26.6 0.0 1.1e-05 25.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO63283.1 - 0.0024 17.2 0.0 0.0055 16.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 AEO63283.1 - 0.0093 16.3 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO63283.1 - 0.0094 16.4 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 AEO63283.1 - 0.021 13.9 0.0 0.12 11.4 0.0 1.9 1 1 0 1 1 1 0 N-6 DNA Methylase tRNA-synt_1 PF00133.17 AEO63284.1 - 4.6e-53 180.1 0.0 2.2e-28 98.6 0.0 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 AEO63284.1 - 2.2e-39 134.6 0.0 6.6e-39 133.1 0.0 1.8 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 AEO63284.1 - 4.8e-31 107.7 0.0 2.8e-22 78.9 0.0 4.2 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 AEO63284.1 - 1.3e-11 44.4 0.0 2.7e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 AEO63284.1 - 0.01 14.9 0.0 3.5 6.6 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 AEO63284.1 - 0.011 14.6 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) tRNA-synt_1c PF00749.16 AEO63284.1 - 0.2 10.2 1.0 1.9 7.0 0.2 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain APH PF01636.18 AEO63285.1 - 2.8e-10 40.3 0.1 8.7e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Poxvirus_B22R PF04395.7 AEO63285.1 - 0.17 11.4 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Poxvirus B22R protein NACHT PF05729.7 AEO63287.1 - 9.6e-16 57.8 1.0 1.6e-13 50.6 0.1 2.4 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 AEO63287.1 - 8.4e-08 32.4 0.1 3.9e-07 30.2 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AEO63287.1 - 3.7e-05 23.8 0.0 0.0002 21.4 0.0 2.2 3 0 0 3 3 3 1 AAA domain KAP_NTPase PF07693.9 AEO63287.1 - 0.0021 17.0 0.0 0.013 14.4 0.0 1.9 1 1 0 2 2 2 1 KAP family P-loop domain TrwB_AAD_bind PF10412.4 AEO63287.1 - 0.0063 15.1 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 AEO63287.1 - 0.022 14.2 0.0 0.046 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain DUF87 PF01935.12 AEO63287.1 - 0.058 13.2 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 AEO63287.1 - 0.097 12.1 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MFS_1 PF07690.11 AEO63289.1 - 4.1e-35 121.1 57.5 7.3e-35 120.3 38.5 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO63289.1 - 2.1e-12 46.0 29.3 2.9e-12 45.5 20.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 AEO63289.1 - 6.3e-10 38.2 34.4 7.8e-08 31.3 11.8 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter Pyr_redox_2 PF07992.9 AEO63290.1 - 3.3e-23 82.6 0.1 4.4e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO63290.1 - 6.3e-08 31.4 0.1 0.00024 19.7 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 AEO63290.1 - 1.1e-06 28.5 0.1 0.025 14.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 AEO63290.1 - 4.4e-06 26.9 0.7 0.21 11.6 0.1 3.0 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AEO63290.1 - 4.6e-05 22.4 0.7 0.0026 16.7 0.1 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO63290.1 - 8.5e-05 22.5 0.0 0.00021 21.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 AEO63290.1 - 0.00019 20.4 4.1 0.073 11.9 1.2 2.9 2 1 1 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 AEO63290.1 - 0.00019 20.4 0.1 0.0005 19.0 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 AEO63290.1 - 0.0042 15.7 0.4 0.0062 15.2 0.3 1.2 1 0 0 1 1 1 1 Tryptophan halogenase FAD_oxidored PF12831.2 AEO63290.1 - 0.0049 15.9 0.0 0.0069 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 AEO63290.1 - 0.0053 15.8 0.1 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 AEO63290.1 - 0.018 14.1 0.5 0.039 12.9 0.2 1.6 1 1 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 AEO63290.1 - 0.034 13.0 0.9 0.21 10.4 0.4 2.0 1 1 1 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 AEO63290.1 - 0.058 12.7 0.3 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IncFII_repA PF02387.10 AEO63290.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 IncFII RepA protein family Acetyltransf_1 PF00583.19 AEO63291.1 - 0.0002 21.2 0.0 0.00037 20.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF3328 PF11807.3 AEO63293.1 - 7.8e-22 78.0 0.1 9.9e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) AA_permease_2 PF13520.1 AEO63294.1 - 2.6e-63 214.0 33.8 4.5e-63 213.2 23.4 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO63294.1 - 1.1e-26 93.2 28.8 1.1e-26 93.2 20.0 1.8 2 0 0 2 2 2 1 Amino acid permease DUF2721 PF11026.3 AEO63294.1 - 4.5 6.9 11.2 6.2 6.4 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) 2-Hacid_dh_C PF02826.14 AEO63295.1 - 1.1e-50 171.2 0.0 1.6e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AEO63295.1 - 2e-15 56.4 0.0 2.7e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AEO63295.1 - 0.00025 20.9 0.0 0.00093 19.0 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 AEO63295.1 - 0.035 13.6 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3684 PF12449.3 AEO63296.1 - 0 1446.3 0.0 0 1446.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 AEO63296.1 - 1.3e-05 24.8 0.0 3.2e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MMtag PF10159.4 AEO63297.1 - 8.1e-30 102.7 2.4 8.1e-30 102.7 1.7 3.0 2 1 0 2 2 2 1 Kinase phosphorylation protein rve PF00665.21 AEO63298.1 - 0.0014 18.7 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Plasmod_dom_1 PF09715.5 AEO63299.1 - 5.4 7.0 9.7 0.15 12.0 1.1 2.4 2 1 1 3 3 3 0 Plasmodium protein of unknown function (Plasmod_dom_1) Med6 PF04934.9 AEO63300.1 - 5.6e-40 136.1 0.0 7.1e-40 135.8 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component HA2 PF04408.18 AEO63301.1 - 1.5e-19 69.9 0.0 4.8e-19 68.2 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AEO63301.1 - 4.5e-14 52.0 0.0 4.8e-13 48.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 AEO63301.1 - 2.1e-12 46.8 0.0 5.6e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 AEO63301.1 - 1.1e-07 31.5 0.1 7.9e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AEO63301.1 - 0.00037 20.6 0.2 0.0027 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 AEO63301.1 - 0.0018 18.1 1.5 0.26 11.1 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.11 AEO63301.1 - 0.02 14.1 0.1 0.059 12.6 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein T2SE PF00437.15 AEO63301.1 - 0.021 13.7 0.0 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 AEO63301.1 - 0.061 12.4 0.0 0.17 10.9 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 AEO63301.1 - 0.25 11.6 9.0 0.34 11.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF2372 PF10178.4 AEO63302.1 - 0.094 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2372) Ribosomal_L18e PF00828.14 AEO63303.1 - 5.7e-33 114.0 0.0 7.8e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Metallophos PF00149.23 AEO63304.1 - 5.5e-42 143.4 1.3 8.8e-42 142.7 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short_C2 PF13561.1 AEO63305.1 - 5.9e-23 81.8 1.6 3.1e-22 79.5 1.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AEO63305.1 - 1.4e-21 77.1 5.7 9.5e-21 74.4 3.9 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO63305.1 - 1.7e-08 34.3 0.3 1.7e-08 34.3 0.2 1.8 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 AEO63305.1 - 0.00035 20.2 0.1 0.00095 18.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 AEO63305.1 - 0.0051 16.2 0.5 0.016 14.6 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 AEO63305.1 - 0.0079 15.3 0.1 0.017 14.3 0.1 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YjeF_N PF03853.10 AEO63305.1 - 0.022 14.3 0.1 0.037 13.6 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus THF_DHG_CYH_C PF02882.14 AEO63305.1 - 0.052 12.6 0.0 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 AEO63305.1 - 0.16 11.6 0.4 0.25 10.9 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PhoD PF09423.5 AEO63306.1 - 1.2e-66 225.1 0.0 1.5e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase TauD PF02668.11 AEO63306.1 - 1.7e-35 122.9 0.0 2.7e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family EMP24_GP25L PF01105.19 AEO63307.1 - 5.3e-48 163.1 1.0 6e-48 162.9 0.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SKIP_SNW PF02731.10 AEO63308.1 - 6.5e-67 223.8 4.7 6.5e-67 223.8 3.3 2.6 3 0 0 3 3 3 1 SKIP/SNW domain DUF4603 PF15376.1 AEO63308.1 - 0.99 6.5 13.3 1.3 6.0 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Glyco_hydro_16 PF00722.16 AEO63309.1 - 2.8e-09 36.5 0.0 9e-09 34.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Herpes_gE PF02480.11 AEO63309.1 - 0.014 13.7 0.0 0.02 13.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E VirB8 PF04335.8 AEO63309.1 - 0.072 12.6 4.4 2.8 7.4 0.2 2.2 2 0 0 2 2 2 0 VirB8 protein Tim17 PF02466.14 AEO63310.1 - 1.8e-49 167.0 12.7 2.1e-49 166.8 8.8 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Permease PF02405.11 AEO63310.1 - 0.42 10.0 4.0 0.93 8.9 0.2 2.0 2 0 0 2 2 2 0 Permease USP7_ICP0_bdg PF12436.3 AEO63311.1 - 2.5e-85 285.6 1.0 3.4e-83 278.7 0.2 3.0 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 AEO63311.1 - 2.2e-75 252.7 7.3 7.2e-72 241.2 0.0 4.2 5 0 0 5 5 5 3 Ubiquitin-specific protease C-terminal UCH PF00443.24 AEO63311.1 - 6.6e-56 189.3 1.7 6.6e-56 189.3 1.2 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO63311.1 - 2.9e-29 102.4 0.2 5e-29 101.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 AEO63311.1 - 8.7e-15 55.0 0.2 6.5e-14 52.2 0.1 2.5 2 0 0 2 2 2 1 MATH domain YukD PF08817.5 AEO63311.1 - 0.046 14.2 0.0 0.81 10.2 0.0 2.9 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD BCDHK_Adom3 PF10436.4 AEO63312.1 - 4.1e-42 143.4 0.0 6.4e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 AEO63312.1 - 1.5e-10 40.7 0.0 8.5e-08 31.9 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AEO63312.1 - 0.0004 20.0 0.0 0.00068 19.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SelP_N PF04592.9 AEO63312.1 - 0.12 11.7 1.8 0.25 10.7 1.2 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Septin PF00735.13 AEO63313.1 - 1.9e-117 391.2 0.5 2.9e-117 390.6 0.3 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 AEO63313.1 - 7.4e-07 29.1 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AEO63313.1 - 2.1e-06 27.3 0.3 4.9e-05 22.8 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 AEO63313.1 - 1.4e-05 24.3 0.0 4e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 AEO63313.1 - 0.0026 18.2 0.1 0.009 16.4 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 AEO63313.1 - 0.0033 17.0 0.1 0.0068 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AEO63313.1 - 0.0065 16.6 0.6 0.022 14.9 0.0 2.2 2 2 0 2 2 2 1 AAA domain IIGP PF05049.8 AEO63313.1 - 0.0075 15.1 0.0 0.014 14.2 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.11 AEO63313.1 - 0.01 14.9 0.0 0.023 13.8 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Pox_A32 PF04665.7 AEO63313.1 - 0.012 14.9 0.1 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 AEO63313.1 - 0.013 15.0 1.1 0.018 14.4 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ras PF00071.17 AEO63313.1 - 0.018 14.4 0.6 0.058 12.7 0.3 1.9 2 1 0 2 2 2 0 Ras family AAA_16 PF13191.1 AEO63313.1 - 0.023 14.6 2.3 0.63 9.9 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain T2SE PF00437.15 AEO63313.1 - 0.029 13.2 0.5 0.094 11.6 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.22 AEO63313.1 - 0.032 14.5 0.2 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 AEO63313.1 - 0.041 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 AEO63313.1 - 0.072 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2968 PF11180.3 AEO63313.1 - 0.075 12.4 7.5 0.22 10.8 5.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) PduV-EutP PF10662.4 AEO63313.1 - 0.081 12.4 0.8 2.6 7.5 0.2 2.7 2 1 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 AEO63313.1 - 0.082 12.7 7.9 0.49 10.2 0.1 3.1 2 1 1 3 3 3 0 Dynamin family ArgK PF03308.11 AEO63313.1 - 0.1 11.3 2.2 0.95 8.1 0.0 2.8 3 0 0 3 3 3 0 ArgK protein RNA_helicase PF00910.17 AEO63313.1 - 0.11 12.7 0.0 0.37 10.9 0.0 2.0 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.12 AEO63313.1 - 0.23 10.9 0.9 10 5.5 0.1 2.6 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Ribosomal_L6e PF01159.14 AEO63313.1 - 0.31 11.3 5.7 5.8 7.2 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e KAP_NTPase PF07693.9 AEO63313.1 - 0.35 9.8 4.0 0.78 8.6 2.8 1.7 1 1 0 1 1 1 0 KAP family P-loop domain Atg14 PF10186.4 AEO63313.1 - 0.36 9.7 8.0 0.87 8.4 5.6 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 AEO63313.1 - 1.2 9.1 8.8 0.56 10.2 3.0 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 AEO63313.1 - 4.2 6.9 9.4 0.92 9.0 3.1 2.4 2 0 0 2 2 2 0 Septum formation initiator Myc-LZ PF02344.10 AEO63313.1 - 8.4 6.1 13.7 4.7 6.9 4.6 3.2 2 1 0 2 2 2 0 Myc leucine zipper domain WD40 PF00400.27 AEO63314.1 - 1.5e-51 170.5 31.1 3.5e-12 45.6 0.0 12.1 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.7 AEO63314.1 - 1.5e-25 89.2 0.0 2.2e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 AEO63314.1 - 3.5e-06 26.8 1.0 0.041 13.5 0.1 5.8 5 1 2 8 8 8 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 AEO63314.1 - 0.00016 19.9 3.2 0.16 10.0 0.0 4.3 2 1 1 4 4 4 3 Nucleoporin Nup120/160 IKI3 PF04762.7 AEO63314.1 - 0.00047 18.1 0.0 0.0085 13.9 0.0 2.2 2 0 0 2 2 2 1 IKI3 family Nbas_N PF15492.1 AEO63314.1 - 0.00095 18.3 0.5 10 5.1 0.0 4.4 3 2 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Utp13 PF08625.6 AEO63314.1 - 0.075 12.6 0.1 0.24 11.0 0.1 2.0 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain DUF4243 PF14027.1 AEO63315.1 - 2.2e-82 277.1 0.1 2.9e-82 276.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Phycoerythr_ab PF02972.9 AEO63315.1 - 0.44 10.1 1.6 9.8 5.8 0.0 2.7 3 0 0 3 3 3 0 Phycoerythrin, alpha/beta chain Exo_endo_phos PF03372.18 AEO63316.1 - 1.3e-26 94.0 0.1 2.2e-26 93.3 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CTD_bind PF04818.8 AEO63318.1 - 1.2e-10 41.4 0.0 2.6e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RIC1 PF07064.8 AEO63318.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 RIC1 DUF936 PF06075.7 AEO63318.1 - 2.8 6.7 15.5 3.7 6.3 10.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) B56 PF01603.15 AEO63319.1 - 2.7e-173 576.2 4.1 3.2e-173 576.0 2.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Tau95 PF09734.4 AEO63320.1 - 3.1e-70 236.9 0.0 4e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit BCS1_N PF08740.6 AEO63321.1 - 4e-45 153.7 0.1 4e-45 153.7 0.1 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 AEO63321.1 - 2.6e-16 59.9 0.0 3.1e-07 30.6 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AEO63321.1 - 0.00035 19.6 0.0 0.00099 18.2 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 AEO63321.1 - 0.00046 20.9 0.1 0.0011 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AEO63321.1 - 0.0031 16.9 0.0 0.01 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 AEO63321.1 - 0.044 13.5 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 AEO63321.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 AEO63321.1 - 0.17 12.1 1.0 0.83 9.9 0.7 2.1 1 1 0 1 1 1 0 AAA domain DUF605 PF04652.11 AEO63321.1 - 0.3 10.4 17.9 0.46 9.8 12.4 1.2 1 0 0 1 1 1 0 Vta1 like Dicty_REP PF05086.7 AEO63321.1 - 0.33 8.6 9.5 0.58 7.8 6.6 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 AEO63321.1 - 0.45 10.2 17.0 1 9.1 11.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) AAA_16 PF13191.1 AEO63321.1 - 0.48 10.3 2.8 0.72 9.8 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain APH PF01636.18 AEO63322.1 - 2.5e-05 24.1 1.2 0.092 12.4 0.1 2.6 1 1 2 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.20 AEO63322.1 - 0.038 13.1 0.1 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Asparaginase PF00710.15 AEO63324.1 - 3.3e-102 341.5 0.0 3.8e-102 341.3 0.0 1.0 1 0 0 1 1 1 1 Asparaginase RVT_1 PF00078.22 AEO63325.1 - 0.0015 17.9 0.2 0.0018 17.6 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chordopox_E11 PF06138.7 AEO63325.1 - 0.088 12.8 2.0 0.1 12.6 1.4 1.1 1 0 0 1 1 1 0 Chordopoxvirus E11 protein Exonuc_V_gamma PF04257.9 AEO63325.1 - 0.11 10.4 0.6 0.14 10.1 0.4 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit Pox_Ag35 PF03286.9 AEO63326.1 - 0.0047 16.4 8.7 0.0068 15.9 6.0 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein PBP_sp32 PF07222.7 AEO63326.1 - 0.056 12.6 4.0 0.074 12.2 2.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF3246 PF11596.3 AEO63326.1 - 0.058 12.6 0.3 0.068 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Glypican PF01153.14 AEO63326.1 - 0.068 11.7 0.7 0.082 11.5 0.5 1.1 1 0 0 1 1 1 0 Glypican Na_trans_assoc PF06512.8 AEO63326.1 - 0.09 12.7 3.1 0.1 12.5 2.2 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated PBP1_TM PF14812.1 AEO63326.1 - 0.1 12.9 22.6 0.094 13.0 3.3 2.3 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 AEO63326.1 - 0.16 9.8 13.4 0.19 9.6 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 AEO63326.1 - 0.24 10.3 12.9 0.32 9.9 8.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TFIIF_alpha PF05793.7 AEO63326.1 - 0.29 9.4 17.6 0.37 9.1 12.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PGA2 PF07543.7 AEO63326.1 - 0.45 10.3 12.0 0.75 9.5 8.3 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF2201_N PF13203.1 AEO63326.1 - 0.83 8.7 6.2 1.2 8.2 4.3 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain Tom22 PF04281.8 AEO63326.1 - 0.91 9.0 6.6 0.28 10.6 0.7 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Daxx PF03344.10 AEO63326.1 - 0.94 7.8 10.1 1.3 7.3 7.0 1.3 1 0 0 1 1 1 0 Daxx Family AF1Q PF15017.1 AEO63326.1 - 1 9.3 8.6 9.5 6.2 0.1 2.2 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator RNase_H2_suC PF08615.6 AEO63326.1 - 1.1 9.0 5.0 26 4.6 3.5 2.0 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) eIF3_subunit PF08597.5 AEO63326.1 - 1.7 8.1 19.9 2.4 7.6 13.8 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1510 PF07423.6 AEO63326.1 - 2.1 7.6 12.8 2.6 7.3 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2151 PF10221.4 AEO63326.1 - 3.5 5.6 5.9 3.9 5.5 4.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator ANAPC15 PF15243.1 AEO63326.1 - 4.4 7.4 15.1 5.7 7.0 5.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 eIF-3c_N PF05470.7 AEO63326.1 - 5.1 5.0 9.1 6.1 4.8 6.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus MFS_1 PF07690.11 AEO63327.1 - 1.1e-39 136.2 49.3 3e-39 134.7 31.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO63327.1 - 8.4e-10 37.8 15.9 8.4e-10 37.8 11.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter NAP PF00956.13 AEO63328.1 - 9e-53 178.8 5.8 9e-53 178.8 4.0 1.9 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) BSP_II PF05432.6 AEO63328.1 - 9.1 5.4 20.9 7.5 5.7 2.6 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF4611 PF15387.1 AEO63328.1 - 9.6 6.4 22.0 2.6 8.2 2.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Glyco_hydro_76 PF03663.9 AEO63329.1 - 1.8e-152 508.0 17.7 2.1e-152 507.7 12.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 AEO63329.1 - 0.02 13.9 8.5 0.13 11.2 0.1 3.1 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Dak1 PF02733.12 AEO63330.1 - 8.4e-81 271.0 4.3 1.3e-80 270.4 3.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 AEO63330.1 - 2.3e-44 151.1 0.4 5.2e-44 149.9 0.1 1.8 2 0 0 2 2 2 1 DAK2 domain ECH_C PF13766.1 AEO63331.1 - 2.5e-35 121.1 0.3 7.4e-35 119.6 0.2 1.8 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 AEO63331.1 - 1.5e-27 96.2 0.0 3.3e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family CTP_transf_1 PF01148.15 AEO63332.1 - 4.3e-06 26.5 10.2 0.00038 20.1 7.0 2.8 1 1 0 1 1 1 1 Cytidylyltransferase family RVT_1 PF00078.22 AEO63333.1 - 0.018 14.3 0.7 0.023 14.0 0.5 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Exonuc_V_gamma PF04257.9 AEO63333.1 - 0.026 12.5 0.5 0.03 12.3 0.4 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit Nop14 PF04147.7 AEO63335.1 - 0.17 9.7 12.7 0.28 9.0 8.8 1.3 1 0 0 1 1 1 0 Nop14-like family PBP_sp32 PF07222.7 AEO63335.1 - 0.18 10.9 4.7 0.32 10.1 3.3 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pox_Ag35 PF03286.9 AEO63335.1 - 0.7 9.3 18.8 0.022 14.2 6.3 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CDC27 PF09507.5 AEO63335.1 - 0.83 8.8 23.3 0.13 11.4 6.3 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 PBP1_TM PF14812.1 AEO63335.1 - 3.5 8.0 27.3 0.32 11.3 3.7 3.0 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PGA2 PF07543.7 AEO63335.1 - 5.2 6.8 15.4 2.4 7.9 8.5 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 RVT_1 PF00078.22 AEO63337.1 - 3.2e-05 23.3 1.2 4e-05 23.0 0.8 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 AEO63339.1 - 4.9e-05 22.7 0.3 4.9e-05 22.7 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ycf54 PF10674.4 AEO63339.1 - 0.12 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) DUF3414 PF11894.3 AEO63341.1 - 0.061 10.2 0.2 0.064 10.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3414) DUF1754 PF08555.5 AEO63343.1 - 1.2e-15 57.8 7.2 2.3e-15 56.9 5.0 1.5 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) DUF1978 PF09321.5 AEO63343.1 - 0.069 12.5 2.3 0.1 12.0 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) IncA PF04156.9 AEO63343.1 - 2 7.9 4.9 2.9 7.4 3.4 1.2 1 0 0 1 1 1 0 IncA protein DUF4544 PF15077.1 AEO63343.1 - 6.5 6.1 7.1 2.9 7.3 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4544) cobW PF02492.14 AEO63345.1 - 6.2e-36 123.4 0.0 9.9e-36 122.8 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 AEO63345.1 - 0.0052 16.4 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 AEO63345.1 - 0.0079 15.9 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 AEO63345.1 - 0.036 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 AEO63345.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 AEO63345.1 - 0.071 13.2 0.0 0.58 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF330 PF03886.8 AEO63345.1 - 0.09 12.1 0.3 0.26 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF330) AAA_14 PF13173.1 AEO63345.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AA_permease PF00324.16 AEO63347.1 - 2.6e-07 29.3 2.3 4.2e-07 28.6 1.6 1.2 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 AEO63348.1 - 1.8e-82 277.0 31.8 2.2e-82 276.7 22.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RNA_pol_L_2 PF13656.1 AEO63349.1 - 4.6e-21 74.0 0.0 6e-21 73.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 AEO63349.1 - 4.5e-08 32.0 0.0 7.2e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DNA_pol_A_exo1 PF01612.15 AEO63350.1 - 9.2e-13 48.0 0.0 1.4e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease DUF342 PF03961.8 AEO63350.1 - 0.21 9.9 0.0 0.28 9.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) WD40 PF00400.27 AEO63351.1 - 9.7e-28 95.0 15.4 1.4e-06 27.9 0.3 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 AEO63351.1 - 1.6e-18 66.4 0.0 2.6e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 AEO63351.1 - 0.0005 18.3 3.2 0.48 8.4 0.1 3.5 1 1 1 3 3 3 3 Nucleoporin Nup120/160 DNA_pol_E_B PF04042.11 AEO63352.1 - 2.9e-53 180.2 0.0 3.7e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PALP PF00291.20 AEO63354.1 - 4.6e-60 203.4 2.0 6.1e-60 203.0 1.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Acetyltransf_3 PF13302.1 AEO63355.1 - 2.3e-24 86.1 0.0 2.9e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO63355.1 - 1.3e-08 34.4 0.1 0.00097 18.8 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_8 PF13523.1 AEO63355.1 - 1.5e-08 34.6 1.2 4.2e-06 26.7 0.8 2.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO63355.1 - 2.4e-05 24.2 0.0 7.6e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 AEO63355.1 - 0.00056 19.8 0.1 0.0054 16.6 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AEO63355.1 - 0.033 14.0 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 AEO63355.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA-synt_1g PF09334.6 AEO63356.1 - 6.6e-117 390.4 0.1 1.1e-116 389.7 0.1 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 AEO63356.1 - 3.6e-23 81.4 5.6 1.4e-10 39.8 0.0 3.9 1 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 AEO63356.1 - 1.9e-08 33.8 0.0 0.00085 18.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 AEO63356.1 - 0.0011 18.6 0.0 0.0047 16.7 0.0 2.0 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA FRD2 PF03197.8 AEO63356.1 - 0.16 12.5 0.1 0.3 11.6 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage FRD2 protein Glyco_hydro_28 PF00295.12 AEO63358.1 - 1.9e-47 161.8 12.0 2.7e-47 161.3 8.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 AEO63358.1 - 0.085 12.6 26.1 0.01 15.5 14.2 2.3 1 1 1 2 2 2 0 Right handed beta helix region Ribosomal_L4 PF00573.17 AEO63359.1 - 2e-41 141.4 1.1 2.9e-41 140.9 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 AEO63359.1 - 7.3e-31 105.8 1.2 1.7e-30 104.7 0.2 2.0 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain DUF3812 PF12757.2 AEO63360.1 - 5.7e-38 129.7 16.5 5.7e-38 129.7 11.4 3.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3812) CAF-1_p150 PF11600.3 AEO63360.1 - 0.0035 16.7 45.8 0.0035 16.7 31.7 2.6 2 1 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Frag1 PF10277.4 AEO63361.1 - 3e-44 151.0 11.4 3.5e-44 150.8 7.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family 7TM_GPCR_Srh PF10318.4 AEO63361.1 - 0.075 11.8 2.9 0.14 10.9 2.0 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh TerC PF03741.11 AEO63361.1 - 3.5 7.0 8.8 3.3 7.1 2.6 2.4 1 1 1 2 2 2 0 Integral membrane protein TerC family Pkinase PF00069.20 AEO63362.1 - 1.6e-64 217.5 0.0 5.2e-64 215.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO63362.1 - 1.9e-33 115.6 0.0 2.8e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO63362.1 - 0.00013 21.0 0.0 0.0003 19.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AEO63362.1 - 0.099 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec10 PF07393.6 AEO63363.1 - 6.4e-181 603.1 0.0 7.8e-181 602.8 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 AEO63363.1 - 1.2e-08 34.4 0.3 7.5e-08 31.9 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 AEO63363.1 - 2.9e-06 26.7 0.0 6.5e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain Vps53_N PF04100.7 AEO63363.1 - 0.016 14.0 0.4 0.045 12.5 0.3 1.7 1 1 0 1 1 1 0 Vps53-like, N-terminal DUF2763 PF10961.3 AEO63363.1 - 3 8.2 6.2 2e+02 2.4 4.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) SNF2_N PF00176.18 AEO63364.1 - 4.8e-57 193.0 0.0 8.1e-57 192.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 AEO63364.1 - 4.6e-09 35.9 11.8 9.2e-09 34.9 8.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AEO63364.1 - 2e-08 33.7 10.4 4e-08 32.7 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO63364.1 - 1.2e-07 31.2 10.1 2.3e-07 30.3 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO63364.1 - 2.4e-07 30.6 11.7 5.1e-07 29.6 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO63364.1 - 1.5e-05 25.0 7.6 3.9e-05 23.6 5.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 AEO63364.1 - 2.5e-05 23.8 10.9 5.1e-05 22.9 7.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 AEO63364.1 - 0.0047 16.6 5.1 0.014 15.0 3.5 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AEO63364.1 - 0.0081 16.0 8.0 0.018 14.8 5.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Helicase_C PF00271.26 AEO63364.1 - 0.053 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Prok-RING_4 PF14447.1 AEO63364.1 - 0.095 12.2 8.5 0.2 11.2 5.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 AEO63364.1 - 0.44 10.3 2.6 1.1 9.1 1.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 AEO63364.1 - 0.72 9.4 8.9 0.34 10.5 4.3 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain IBR PF01485.16 AEO63364.1 - 0.89 9.4 6.2 2.2 8.1 4.3 1.6 1 0 0 1 1 1 0 IBR domain IGR PF09597.5 AEO63365.1 - 1.2e-24 85.8 0.1 2.1e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 IGR protein motif SAM_1 PF00536.25 AEO63365.1 - 0.0045 17.1 0.0 0.0094 16.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) bZIP_1 PF00170.16 AEO63367.1 - 0.0035 17.2 4.7 0.007 16.2 3.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AEO63367.1 - 0.025 14.4 7.6 0.025 14.4 5.3 1.7 2 0 0 2 2 2 0 Basic region leucine zipper SOBP PF15279.1 AEO63367.1 - 0.08 13.3 5.4 0.12 12.7 3.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Glyco_hydro_63 PF03200.11 AEO63368.1 - 6.9e-245 814.6 0.0 5.9e-244 811.5 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 AEO63368.1 - 3.2e-05 22.7 0.0 5.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 AEO63368.1 - 0.0024 16.6 0.0 0.0047 15.6 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase RabGAP-TBC PF00566.13 AEO63369.1 - 6e-34 117.3 2.6 6e-34 117.3 1.8 2.1 2 1 0 2 2 2 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 AEO63369.1 - 9.9e-10 38.0 0.0 0.00019 20.7 0.0 3.9 4 0 0 4 4 4 3 Domain of unknown function (DUF3548) Mso1_Sec1_bdg PF14475.1 AEO63370.1 - 1.1e-19 69.5 0.0 1.7e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.12 AEO63371.1 - 3.7e-30 104.7 1.1 3.7e-30 104.7 0.7 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 AEO63371.1 - 3.3e-23 81.6 49.2 2.6e-21 75.6 9.0 3.5 2 1 1 3 3 3 2 Mak16 protein C-terminal region CENP-T PF15511.1 AEO63371.1 - 0.013 14.8 16.6 0.016 14.5 11.5 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BUD22 PF09073.5 AEO63371.1 - 4 6.3 42.2 8 5.4 29.2 1.5 1 1 0 1 1 1 0 BUD22 TrmE_N PF10396.4 AEO63372.1 - 3e-34 117.4 0.0 7.4e-34 116.1 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 AEO63372.1 - 1e-19 70.6 0.1 3.7e-19 68.9 0.0 2.0 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 AEO63372.1 - 1.5e-17 63.6 0.0 3e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO63372.1 - 2e-06 27.2 0.0 1.6e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AEO63372.1 - 0.0007 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 AEO63372.1 - 0.0016 18.9 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 AEO63372.1 - 0.016 14.4 0.0 0.037 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 AEO63372.1 - 0.033 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Glyco_hydro_3_C PF01915.17 AEO63372.1 - 0.039 13.4 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain P5CR_dimer PF14748.1 AEO63372.1 - 0.059 13.3 0.2 0.58 10.1 0.0 2.6 3 0 0 3 3 3 0 Pyrroline-5-carboxylate reductase dimerisation MMS19_N PF14500.1 AEO63372.1 - 0.2 10.8 0.8 0.31 10.2 0.0 1.7 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Monellin PF09200.5 AEO63373.1 - 0.21 11.2 0.6 0.21 11.2 0.4 2.0 2 0 0 2 2 2 0 Monellin SecE PF00584.15 AEO63375.1 - 1.3e-11 43.8 0.0 1.4e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Transthyretin PF00576.16 AEO63377.1 - 1.5e-22 79.6 2.0 2e-13 50.2 0.0 2.7 2 1 1 3 3 3 2 HIUase/Transthyretin family ArsA_ATPase PF02374.10 AEO63379.1 - 5.5e-112 373.7 0.0 6.2e-112 373.5 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 AEO63379.1 - 7.2e-17 61.4 0.2 6.2e-16 58.3 0.2 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 AEO63379.1 - 8.1e-09 35.5 0.0 4.9e-08 33.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 AEO63379.1 - 4.7e-06 25.9 0.0 9e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 AEO63379.1 - 3.6e-05 23.3 0.1 0.0013 18.2 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 AEO63379.1 - 0.0048 16.3 0.1 0.01 15.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO63379.1 - 0.0094 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 AEO63379.1 - 0.021 14.2 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein YhjQ PF06564.7 AEO63379.1 - 0.023 14.0 0.0 0.057 12.7 0.0 1.6 1 0 0 1 1 1 0 YhjQ protein MipZ PF09140.6 AEO63379.1 - 0.025 13.6 0.0 0.051 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase MipZ NB-ARC PF00931.17 AEO63379.1 - 0.094 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 AEO63379.1 - 0.1 12.8 0.1 0.22 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 AEO63379.1 - 0.14 11.0 0.2 0.33 9.8 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein DWNN PF08783.6 AEO63380.1 - 7.1e-28 96.3 0.0 1.4e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 AEO63380.1 - 0.0013 18.2 5.3 0.004 16.5 3.7 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 AEO63380.1 - 0.0042 16.9 1.5 0.0097 15.7 1.0 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-RING_6 PF14835.1 AEO63380.1 - 0.013 15.2 1.9 0.024 14.3 1.3 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-CCHC_3 PF13917.1 AEO63380.1 - 0.022 14.5 0.5 0.057 13.1 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-RING_4 PF14570.1 AEO63380.1 - 0.072 12.6 6.3 0.18 11.3 4.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Dicty_REP PF05086.7 AEO63380.1 - 0.11 10.1 0.2 0.17 9.6 0.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-Nse PF11789.3 AEO63380.1 - 0.35 10.4 6.0 0.77 9.3 4.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 AEO63380.1 - 1.9 8.3 12.1 0.13 12.0 4.5 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AEO63380.1 - 2.2 8.2 11.1 3.8 7.4 7.1 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 AEO63380.1 - 3.3 7.4 9.2 6.8 6.4 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PRELI PF04707.9 AEO63381.1 - 4.3e-20 71.8 0.0 2.4e-17 62.9 0.0 2.1 1 1 1 2 2 2 2 PRELI-like family Peptidase_S10 PF00450.17 AEO63382.1 - 3.7e-83 280.0 0.0 6.4e-83 279.2 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase RF-1 PF00472.15 AEO63383.1 - 1.5e-33 114.9 5.0 1.5e-33 114.9 3.4 1.7 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 AEO63383.1 - 3.2e-27 94.5 0.0 9.2e-27 93.0 0.0 1.8 2 0 0 2 2 2 1 PCRF domain MIR PF02815.14 AEO63383.1 - 0.022 14.3 0.2 0.066 12.7 0.1 1.7 1 1 0 1 1 1 0 MIR domain tRNA-synt_1b PF00579.20 AEO63384.1 - 2.3e-16 59.7 0.3 1.7e-08 33.9 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (W and Y) GST_C_2 PF13410.1 AEO63385.1 - 2.6e-05 24.0 5.4 0.00012 21.8 3.7 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 AEO63385.1 - 0.00014 21.7 0.0 0.00052 19.9 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 AEO63385.1 - 0.006 17.0 0.1 0.014 15.8 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 AEO63385.1 - 0.025 14.7 0.1 0.46 10.7 0.0 2.6 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 AEO63385.1 - 0.036 14.0 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PPTA PF01239.17 AEO63385.1 - 0.076 12.3 0.8 0.15 11.4 0.5 1.4 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat G_glu_transpept PF01019.16 AEO63386.1 - 1.5e-141 472.4 0.0 1.7e-141 472.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Glutaredoxin PF00462.19 AEO63387.1 - 1.9e-10 40.5 0.0 0.00034 20.5 0.0 2.6 3 0 0 3 3 3 2 Glutaredoxin adh_short PF00106.20 AEO63388.1 - 4.6e-16 59.1 2.6 9.4e-16 58.1 1.4 1.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO63388.1 - 2.6e-10 40.2 0.2 4.4e-10 39.5 0.2 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO63388.1 - 0.00072 19.3 0.0 0.0029 17.4 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AEO63388.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3592 PF12158.3 AEO63388.1 - 0.059 13.1 0.3 0.26 11.0 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) NAD_binding_4 PF07993.7 AEO63388.1 - 0.15 10.9 0.3 0.38 9.6 0.2 1.6 1 1 0 1 1 1 0 Male sterility protein CoA_transf_3 PF02515.12 AEO63389.1 - 1.4e-43 148.3 2.4 4.8e-39 133.5 1.0 2.2 1 1 1 2 2 2 2 CoA-transferase family III AUX_IAA PF02309.11 AEO63389.1 - 0.23 11.1 0.0 0.38 10.4 0.0 1.2 1 0 0 1 1 1 0 AUX/IAA family Dynamin_M PF01031.15 AEO63390.1 - 2.3e-107 358.1 1.9 3.2e-107 357.7 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 AEO63390.1 - 9.2e-57 191.5 0.0 2e-56 190.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 AEO63390.1 - 9e-29 99.2 7.5 1.1e-28 98.9 3.5 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 AEO63390.1 - 6e-05 22.9 0.3 0.0013 18.6 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AEO63390.1 - 0.0063 17.0 0.0 0.023 15.1 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein WD40 PF00400.27 AEO63391.1 - 6.6e-31 105.0 14.3 6.9e-09 35.2 0.2 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 AEO63391.1 - 0.00083 19.1 0.0 0.059 13.0 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A CLTH PF10607.4 AEO63391.1 - 0.0034 17.0 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PD40 PF07676.7 AEO63391.1 - 0.0045 16.6 0.6 24 4.7 0.0 4.0 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat RVT_1 PF00078.22 AEO63392.1 - 0.00036 19.9 0.3 0.00047 19.5 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.5 AEO63393.1 - 0.0011 18.0 8.7 0.002 17.2 6.0 1.3 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.7 AEO63393.1 - 0.0034 15.3 7.0 0.0045 15.0 4.9 1.1 1 0 0 1 1 1 1 Nop14-like family Myc_N PF01056.13 AEO63393.1 - 0.0038 16.4 6.2 0.013 14.7 4.3 1.9 1 0 0 1 1 1 1 Myc amino-terminal region CDC45 PF02724.9 AEO63393.1 - 0.51 8.3 10.1 0.7 7.8 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.6 AEO63393.1 - 0.7 8.8 12.2 1 8.2 8.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) NOA36 PF06524.7 AEO63393.1 - 1.2 8.3 10.1 1.8 7.7 7.0 1.2 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.8 AEO63393.1 - 1.8 8.3 18.4 0.027 14.3 3.5 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.10 AEO63393.1 - 2.7 6.5 4.1 3.9 5.9 2.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 AEO63393.1 - 3.2 6.1 23.7 0.086 11.3 11.9 1.6 2 0 0 2 2 2 0 Daxx Family TRAP_alpha PF03896.11 AEO63393.1 - 4.4 6.2 7.1 7.3 5.4 4.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPP4R2 PF09184.6 AEO63393.1 - 9.7 5.6 16.1 16 4.9 11.2 1.3 1 0 0 1 1 1 0 PPP4R2 CAS_CSE1 PF03378.10 AEO63394.1 - 2.2e-169 563.3 0.0 3.6e-169 562.6 0.0 1.3 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 AEO63394.1 - 1.6e-135 451.4 5.9 1.9e-133 444.6 4.1 2.3 1 1 0 1 1 1 1 Cse1 DUF3384 PF11864.3 AEO63395.1 - 1.3e-110 370.0 0.0 3.7e-110 368.5 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 AEO63395.1 - 2.7e-56 189.9 0.0 7.6e-56 188.4 0.0 1.8 2 0 0 2 2 2 1 Rap/ran-GAP Tuberin PF03542.11 AEO63395.1 - 7.3e-34 117.3 0.3 4.3e-30 104.9 0.0 2.6 2 0 0 2 2 2 2 Tuberin Acetyltransf_1 PF00583.19 AEO63396.1 - 1.8e-08 34.3 0.0 6.5e-07 29.2 0.0 2.7 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AEO63396.1 - 4.1e-07 30.1 0.1 2.4e-05 24.4 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO63396.1 - 0.00033 20.5 0.0 0.0031 17.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO63396.1 - 0.0024 17.9 0.0 0.012 15.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO63396.1 - 0.046 13.4 0.1 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein CENP-I PF07778.6 AEO63397.1 - 1.2e-104 350.3 0.0 1e-52 179.0 0.0 2.2 1 1 1 2 2 2 2 Mis6 UPF0139 PF03669.8 AEO63397.1 - 0.036 13.5 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) Stork_head PF10264.4 AEO63397.1 - 0.13 12.4 0.2 6.5 7.0 0.0 2.6 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain ABC_tran PF00005.22 AEO63398.1 - 3e-14 53.4 0.0 2.1e-13 50.7 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AEO63398.1 - 4.1e-10 40.0 0.0 0.0005 20.1 0.2 2.1 1 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 AEO63398.1 - 0.00021 20.4 0.0 0.43 9.5 0.0 2.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 AEO63398.1 - 0.00059 19.3 0.1 0.0011 18.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 AEO63398.1 - 0.00088 16.7 0.4 0.0012 16.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) SMC_N PF02463.14 AEO63398.1 - 0.001 18.3 0.0 0.65 9.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AEO63398.1 - 0.0028 17.6 1.2 0.01 15.8 0.8 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 AEO63398.1 - 0.01 16.6 0.2 0.019 15.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 AEO63398.1 - 0.011 15.1 0.0 0.025 14.0 0.0 1.6 1 1 0 1 1 1 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 AEO63398.1 - 0.014 14.8 0.1 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 AEO63398.1 - 0.016 15.5 0.0 0.023 15.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AEO63398.1 - 0.023 14.6 1.2 0.034 14.1 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 AEO63398.1 - 0.025 14.7 0.2 0.26 11.4 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 AEO63398.1 - 0.034 13.5 1.2 0.08 12.3 0.8 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AEO63398.1 - 0.039 14.0 0.2 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 AEO63398.1 - 0.077 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arf PF00025.16 AEO63398.1 - 0.09 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family NACHT PF05729.7 AEO63398.1 - 0.15 11.6 0.2 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.1 AEO63398.1 - 0.17 10.2 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AEO63398.1 - 0.19 11.6 0.1 0.77 9.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 AEO63398.1 - 0.19 11.6 0.6 0.37 10.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain Transglut_core PF01841.14 AEO63399.1 - 1.4e-10 41.3 0.2 4.1e-10 39.8 0.1 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily SH3_2 PF07653.12 AEO63399.1 - 1.2e-08 34.2 0.1 2.6e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AEO63399.1 - 5.3e-06 25.7 1.2 2.3e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 AEO63399.1 - 0.00012 21.5 0.1 0.0003 20.3 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.20 AEO63400.1 - 1.4e-68 230.8 0.0 1.9e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO63400.1 - 1.8e-48 164.8 0.0 2.6e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO63400.1 - 1.8e-05 23.8 0.0 0.00016 20.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RAI1 PF08652.6 AEO63401.1 - 7.6e-29 99.3 0.0 1.3e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Sec8_exocyst PF04048.9 AEO63402.1 - 9.9e-50 167.8 0.5 2.2e-49 166.7 0.3 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 AEO63402.1 - 7.2e-10 38.2 1.9 1.3e-09 37.4 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) YcbB PF08664.5 AEO63402.1 - 0.0088 15.8 0.4 0.02 14.6 0.3 1.6 1 0 0 1 1 1 1 YcbB domain IZUMO PF15005.1 AEO63402.1 - 0.08 12.9 3.6 1.5 8.8 0.2 3.1 3 0 0 3 3 3 0 Izumo sperm-egg fusion SMI1_KNR4 PF09346.5 AEO63404.1 - 2.1e-36 124.8 0.0 3.6e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) UPF0220 PF05255.6 AEO63405.1 - 5.7e-63 211.1 3.2 6.3e-63 210.9 2.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Pkinase PF00069.20 AEO63408.1 - 2.5e-64 216.9 0.0 3.2e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO63408.1 - 9.5e-26 90.4 0.0 1.2e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO63408.1 - 4.2e-08 32.5 0.0 2.9e-07 29.7 0.0 1.9 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 AEO63408.1 - 0.0011 18.7 0.1 0.0049 16.6 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO63408.1 - 0.039 13.5 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MIF4G_like PF09088.6 AEO63409.1 - 3e-86 287.7 0.1 4.6e-86 287.1 0.1 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 AEO63409.1 - 1.5e-53 181.6 0.0 2.1e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 AEO63409.1 - 0.095 12.1 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 MIF4G domain RRM_1 PF00076.17 AEO63410.1 - 7.2e-35 118.4 0.0 3.1e-16 58.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO63410.1 - 2.5e-18 65.8 0.0 4.3e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO63410.1 - 4e-17 61.8 0.0 7.5e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 AEO63410.1 - 0.00098 18.5 0.1 0.86 9.1 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain Limkain-b1 PF11608.3 AEO63410.1 - 0.008 15.9 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 2 Limkain b1 Tom7 PF08038.7 AEO63411.1 - 6.3e-20 70.3 0.2 7.2e-20 70.1 0.1 1.0 1 0 0 1 1 1 1 TOM7 family Mito_carr PF00153.22 AEO63412.1 - 2.8e-58 193.6 0.8 2.3e-19 68.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.21 AEO63413.1 - 7.4e-20 70.0 24.2 1.4e-06 28.2 0.4 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO63413.1 - 5.9e-16 57.8 25.4 6e-09 35.7 0.5 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO63413.1 - 6.3e-16 57.4 22.0 0.00046 20.3 0.3 4.9 5 0 0 5 5 4 4 C2H2-type zinc finger GAGA PF09237.6 AEO63413.1 - 0.0014 18.1 4.6 0.0074 15.8 1.4 2.6 1 1 1 2 2 2 1 GAGA factor C1_3 PF07649.7 AEO63413.1 - 0.042 13.9 0.7 16 5.6 0.1 2.7 2 0 0 2 2 2 0 C1-like domain DUF3437 PF11919.3 AEO63413.1 - 0.1 12.3 1.6 0.41 10.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) CHORD PF04968.7 AEO63413.1 - 0.25 11.6 3.7 13 6.1 0.1 2.7 2 0 0 2 2 2 0 CHORD zf-C2H2_jaz PF12171.3 AEO63413.1 - 0.44 10.7 0.1 0.44 10.7 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 AEO63413.1 - 0.45 10.8 14.9 0.13 12.5 0.7 3.9 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-met PF12874.2 AEO63413.1 - 0.52 10.5 14.3 3 8.1 0.1 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 AEO63413.1 - 0.64 10.1 13.5 0.23 11.6 2.1 3.1 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 AEO63413.1 - 0.7 10.0 6.9 0.14 12.2 0.3 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF4379 PF14311.1 AEO63413.1 - 0.98 9.2 4.6 2 8.2 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4379) DUF629 PF04780.7 AEO63413.1 - 3.2 6.1 7.0 13 4.1 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF629) AflR PF08493.5 AEO63413.1 - 7.4 5.5 9.3 18 4.2 6.4 1.6 1 0 0 1 1 1 0 Aflatoxin regulatory protein Urm1 PF09138.6 AEO63414.1 - 3.1e-31 107.3 0.0 3.5e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 AEO63414.1 - 0.013 15.8 0.0 0.015 15.7 0.0 1.3 1 1 0 1 1 1 0 ThiS family WD40 PF00400.27 AEO63415.1 - 3.8e-61 200.9 10.3 2.2e-07 30.4 0.1 12.6 13 0 0 13 13 13 10 WD domain, G-beta repeat DUF3317 PF11779.3 AEO63416.1 - 2.3e-15 55.7 2.7 3e-15 55.4 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) RF-1 PF00472.15 AEO63417.1 - 2.3e-25 88.6 3.4 2.3e-25 88.6 2.4 2.3 1 1 1 2 2 2 1 RF-1 domain Myc_N PF01056.13 AEO63417.1 - 0.015 14.4 7.6 0.019 14.1 5.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Herpes_gE PF02480.11 AEO63417.1 - 0.026 12.8 1.3 0.029 12.6 0.9 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Pox_Ag35 PF03286.9 AEO63417.1 - 0.028 13.9 12.3 0.042 13.3 8.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein AAA_23 PF13476.1 AEO63417.1 - 0.037 14.3 6.6 0.049 13.9 4.5 1.2 1 0 0 1 1 1 0 AAA domain XRN_N PF03159.13 AEO63417.1 - 0.063 12.6 5.7 0.085 12.2 3.9 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Nucleo_P87 PF07267.6 AEO63417.1 - 0.084 11.5 8.0 0.1 11.3 5.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PPP4R2 PF09184.6 AEO63417.1 - 0.1 12.1 11.4 0.16 11.5 7.9 1.3 1 0 0 1 1 1 0 PPP4R2 VID27 PF08553.5 AEO63417.1 - 0.19 9.9 14.7 0.24 9.5 10.2 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF2413 PF10310.4 AEO63417.1 - 0.36 9.6 14.7 0.49 9.1 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) CDC45 PF02724.9 AEO63417.1 - 0.43 8.5 16.9 0.53 8.2 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 AEO63417.1 - 0.87 9.3 10.0 1.3 8.8 6.9 1.3 1 0 0 1 1 1 0 DDHD domain Effector_1 PF04518.7 AEO63417.1 - 1.1 8.2 4.1 1.3 7.9 2.9 1.1 1 0 0 1 1 1 0 Effector from type III secretion system HAUS6_N PF14661.1 AEO63417.1 - 1.1 8.5 11.6 1.5 8.1 8.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Spore_coat_CotO PF14153.1 AEO63417.1 - 1.2 8.5 16.0 1.5 8.2 11.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Daxx PF03344.10 AEO63417.1 - 1.7 7.0 27.8 2.1 6.7 19.3 1.1 1 0 0 1 1 1 0 Daxx Family PBP_sp32 PF07222.7 AEO63417.1 - 1.9 7.5 13.2 2.7 7.0 9.1 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Nucleoplasmin PF03066.10 AEO63417.1 - 4.4 6.8 19.9 8.9 5.8 13.8 1.5 1 0 0 1 1 1 0 Nucleoplasmin CobT PF06213.7 AEO63417.1 - 4.8 6.2 24.5 3.5 6.6 16.2 1.3 1 1 0 1 1 1 0 Cobalamin biosynthesis protein CobT GAGA_bind PF06217.7 AEO63417.1 - 4.9 7.0 8.1 5.9 6.7 5.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Ycf1 PF05758.7 AEO63417.1 - 5.4 4.5 9.9 5.2 4.6 6.8 1.1 1 0 0 1 1 1 0 Ycf1 eIF-3c_N PF05470.7 AEO63417.1 - 5.4 4.9 13.6 6.2 4.7 9.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Presenilin PF01080.12 AEO63417.1 - 8.7 5.0 5.4 10 4.8 3.7 1.1 1 0 0 1 1 1 0 Presenilin TRAP_alpha PF03896.11 AEO63417.1 - 9.3 5.1 13.1 14 4.5 9.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Actin PF00022.14 AEO63418.1 - 4.1e-159 529.2 0.0 4.7e-159 529.0 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 AEO63418.1 - 0.039 14.3 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fes1 PF08609.5 AEO63419.1 - 5.5e-36 122.9 0.7 1.4e-35 121.6 0.5 1.7 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 Arm PF00514.18 AEO63419.1 - 9.9e-06 25.1 0.5 0.091 12.6 0.0 2.6 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 AEO63419.1 - 0.00024 20.8 0.3 0.14 12.2 0.0 2.7 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.1 AEO63419.1 - 0.00028 21.1 3.8 0.00078 19.6 2.2 2.2 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 AEO63419.1 - 0.0022 18.4 2.5 0.0062 16.9 0.9 2.5 1 1 1 2 2 2 2 HEAT-like repeat Aconitase_B_N PF11791.3 AEO63419.1 - 0.034 13.9 0.0 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 Aconitate B N-terminal domain AAA_22 PF13401.1 AEO63419.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_L5_C PF00673.16 AEO63420.1 - 8.4e-22 76.7 0.0 1.3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 AEO63420.1 - 0.00032 20.4 0.0 0.00051 19.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 CaATP_NAI PF12515.3 AEO63420.1 - 0.059 12.8 0.1 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain MMR_HSR1 PF01926.18 AEO63421.1 - 6.7e-18 64.7 0.1 1.3e-15 57.4 0.0 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO63421.1 - 2.2e-07 30.2 0.2 1.3e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 AEO63421.1 - 0.00018 20.7 0.0 0.00031 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 AEO63421.1 - 0.00097 18.9 0.1 0.033 14.0 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.11 AEO63421.1 - 0.0097 15.0 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 AEO63421.1 - 0.022 15.2 0.0 0.052 14.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 AEO63421.1 - 0.074 13.1 1.0 2.5 8.2 0.0 3.0 4 0 0 4 4 4 0 AAA domain LTV PF04180.9 AEO63422.1 - 1.4e-101 341.0 14.4 1.7e-101 340.7 10.0 1.0 1 0 0 1 1 1 1 Low temperature viability protein Aminotran_1_2 PF00155.16 AEO63423.1 - 1.8e-09 37.0 0.0 8.6e-08 31.5 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II FMO-like PF00743.14 AEO63424.1 - 2.9e-45 154.4 0.0 1.3e-25 89.6 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 AEO63424.1 - 4.3e-16 59.5 0.1 7.8e-15 55.4 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO63424.1 - 6.5e-14 51.9 0.6 7.4e-13 48.5 0.0 2.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 AEO63424.1 - 3e-10 39.5 1.2 2.4e-08 33.2 0.0 2.9 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 AEO63424.1 - 2.9e-09 37.0 0.0 0.00023 21.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO63424.1 - 3.2e-07 30.2 0.0 7.2e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 AEO63424.1 - 7.9e-06 25.1 0.0 0.00013 21.1 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 AEO63424.1 - 1.9e-05 23.7 0.4 0.051 12.4 0.1 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AEO63424.1 - 0.0086 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 AEO63424.1 - 0.0099 16.2 0.1 0.39 11.1 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO63424.1 - 0.03 12.8 0.7 0.071 11.5 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 AEO63424.1 - 0.067 12.0 0.5 1.1 8.0 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Amino_oxidase PF01593.19 AEO63424.1 - 0.071 12.1 0.2 8.3 5.3 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.15 AEO63424.1 - 0.084 12.9 0.0 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Strep_67kDa_ant PF06100.6 AEO63424.1 - 0.27 9.5 0.0 0.47 8.7 0.0 1.4 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Pkinase PF00069.20 AEO63425.1 - 2.3e-30 105.6 0.0 3.1e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO63425.1 - 8.9e-09 34.7 0.0 2.7e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 AEO63425.1 - 0.0015 18.3 0.6 0.009 15.7 0.3 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 AEO63425.1 - 0.0053 16.1 0.0 0.0083 15.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 AEO63425.1 - 0.021 13.8 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 AEO63425.1 - 0.022 14.1 0.1 0.037 13.3 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 AEO63425.1 - 0.031 13.0 0.1 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase POT1 PF02765.12 AEO63427.1 - 1.3e-08 34.8 0.0 2.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 RVT_1 PF00078.22 AEO63428.1 - 8.4e-05 22.0 0.5 0.00011 21.6 0.4 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ycf54 PF10674.4 AEO63428.1 - 0.064 13.3 0.2 0.09 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) DUF3658 PF12395.3 AEO63428.1 - 0.16 11.5 0.5 0.27 10.8 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function Siva PF05458.7 AEO63430.1 - 0.62 9.6 18.8 0.27 10.8 2.3 3.1 3 0 0 3 3 3 0 Cd27 binding protein (Siva) FYVE_2 PF02318.11 AEO63430.1 - 1.1 9.1 24.2 3.1 7.7 0.2 3.6 4 0 0 4 4 4 0 FYVE-type zinc finger DUF3279 PF11682.3 AEO63430.1 - 3.8 7.1 18.2 0.44 10.1 1.3 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3279) Clr2 PF10383.4 AEO63431.1 - 2.7e-23 82.4 0.0 1.2e-22 80.3 0.0 2.0 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 Pex14_N PF04695.8 AEO63431.1 - 0.057 13.4 4.2 0.1 12.6 2.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 AEO63431.1 - 3.3 7.3 6.3 4.9 6.7 4.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 AEO63431.1 - 4.7 5.3 19.1 8.6 4.4 13.1 1.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 AIG2 PF06094.7 AEO63433.1 - 1.1e-05 25.8 0.0 1.9e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family Pox_Ag35 PF03286.9 AEO63434.1 - 0.0047 16.4 8.7 0.0068 15.9 6.0 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein PBP_sp32 PF07222.7 AEO63434.1 - 0.056 12.6 4.0 0.074 12.2 2.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF3246 PF11596.3 AEO63434.1 - 0.058 12.6 0.3 0.068 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Glypican PF01153.14 AEO63434.1 - 0.068 11.7 0.7 0.082 11.5 0.5 1.1 1 0 0 1 1 1 0 Glypican Na_trans_assoc PF06512.8 AEO63434.1 - 0.09 12.7 3.1 0.1 12.5 2.2 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated PBP1_TM PF14812.1 AEO63434.1 - 0.1 12.9 22.6 0.094 13.0 3.3 2.3 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 AEO63434.1 - 0.16 9.8 13.4 0.19 9.6 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 AEO63434.1 - 0.24 10.3 12.9 0.32 9.9 8.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TFIIF_alpha PF05793.7 AEO63434.1 - 0.29 9.4 17.6 0.37 9.1 12.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PGA2 PF07543.7 AEO63434.1 - 0.45 10.3 12.0 0.75 9.5 8.3 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF2201_N PF13203.1 AEO63434.1 - 0.83 8.7 6.2 1.2 8.2 4.3 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain Tom22 PF04281.8 AEO63434.1 - 0.91 9.0 6.6 0.28 10.6 0.7 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Daxx PF03344.10 AEO63434.1 - 0.94 7.8 10.1 1.3 7.3 7.0 1.3 1 0 0 1 1 1 0 Daxx Family AF1Q PF15017.1 AEO63434.1 - 1 9.3 8.6 9.5 6.2 0.1 2.2 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator RNase_H2_suC PF08615.6 AEO63434.1 - 1.1 9.0 5.0 26 4.6 3.5 2.0 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) eIF3_subunit PF08597.5 AEO63434.1 - 1.7 8.1 19.9 2.4 7.6 13.8 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1510 PF07423.6 AEO63434.1 - 2.1 7.6 12.8 2.6 7.3 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2151 PF10221.4 AEO63434.1 - 3.5 5.6 5.9 3.9 5.5 4.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator ANAPC15 PF15243.1 AEO63434.1 - 4.4 7.4 15.1 5.7 7.0 5.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 eIF-3c_N PF05470.7 AEO63434.1 - 5.1 5.0 9.1 6.1 4.8 6.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Malic_M PF03949.10 AEO63435.1 - 1.3e-88 296.8 0.0 2e-88 296.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 AEO63435.1 - 8e-71 237.3 0.0 1.4e-70 236.5 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain LRR_8 PF13855.1 AEO63436.1 - 1.4e-08 34.3 0.2 0.0054 16.4 0.4 4.3 3 1 1 4 4 4 2 Leucine rich repeat GATA PF00320.22 AEO63436.1 - 8.6e-06 25.0 5.0 4e-05 22.8 1.4 2.5 2 0 0 2 2 2 1 GATA zinc finger LRR_4 PF12799.2 AEO63436.1 - 2.5e-05 23.7 0.0 0.25 10.9 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 AEO63436.1 - 0.0001 22.0 4.7 0.22 11.7 0.0 6.4 9 0 0 9 9 9 1 Leucine Rich repeat LRR_7 PF13504.1 AEO63436.1 - 0.003 17.4 3.2 56 4.6 0.0 6.4 7 0 0 7 7 7 0 Leucine rich repeat LRR_1 PF00560.28 AEO63436.1 - 0.0051 16.6 0.1 1.2e+02 3.3 0.0 5.4 6 1 0 6 6 6 0 Leucine Rich Repeat SRP-alpha_N PF04086.8 AEO63436.1 - 2.9 7.2 8.6 4.6 6.5 6.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NARP1 PF12569.3 AEO63436.1 - 6.1 5.4 7.3 8.8 4.9 5.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SNF2_N PF00176.18 AEO63437.1 - 1.2e-61 208.0 0.0 2e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO63437.1 - 2.1e-12 46.7 0.0 5.4e-12 45.3 0.0 1.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 AEO63437.1 - 2.7e-08 33.3 9.7 2.7e-08 33.3 6.7 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 AEO63437.1 - 4.3e-06 26.3 0.0 9.6e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 AEO63437.1 - 7e-06 25.9 0.0 2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.1 AEO63437.1 - 9.1e-05 22.4 8.8 9.1e-05 22.4 6.1 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO63437.1 - 0.00011 21.9 9.4 0.00011 21.9 6.5 2.2 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AEO63437.1 - 0.00024 20.6 7.8 0.00024 20.6 5.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO63437.1 - 0.0041 16.8 9.3 0.0041 16.8 6.5 2.4 2 0 0 2 2 1 1 zinc-RING finger domain CCD PF07860.6 AEO63437.1 - 0.071 12.5 0.0 0.23 10.9 0.0 1.8 1 0 0 1 1 1 0 WisP family C-Terminal Region zf-RING_6 PF14835.1 AEO63437.1 - 0.094 12.5 2.8 0.26 11.0 2.0 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 AEO63437.1 - 2 8.0 9.0 0.35 10.4 3.2 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 AEO63437.1 - 2.1 8.5 13.1 0.047 13.8 3.0 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger DUF1793 PF08760.6 AEO63438.1 - 2.3e-77 258.7 0.1 6e-77 257.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) RRM_1 PF00076.17 AEO63439.1 - 2.4e-19 68.7 0.0 3.6e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO63439.1 - 3.9e-17 61.9 0.0 6.1e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO63439.1 - 1.2e-11 44.3 0.0 1.6e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_membrane PF00664.18 AEO63440.1 - 7.5e-50 169.8 40.9 2.4e-28 99.3 13.1 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 AEO63440.1 - 3.2e-47 160.2 0.0 1.1e-26 93.8 0.0 2.9 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AEO63440.1 - 5.4e-06 26.5 0.2 1.1 9.1 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 AEO63440.1 - 2.4e-05 24.4 0.1 0.087 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 AEO63440.1 - 3.1e-05 24.4 0.5 0.13 12.7 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein SMC_N PF02463.14 AEO63440.1 - 0.00011 21.5 0.1 4.8 6.3 0.0 3.4 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 AEO63440.1 - 0.00016 20.8 0.1 0.075 12.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.1 AEO63440.1 - 0.00021 20.7 0.5 0.66 9.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 AEO63440.1 - 0.00028 20.8 1.4 0.19 11.6 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 AEO63440.1 - 0.00078 20.2 3.4 0.19 12.5 0.4 2.9 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 AEO63440.1 - 0.00087 18.1 1.3 0.57 8.9 0.1 2.6 2 0 0 2 2 2 2 ArgK protein AAA_25 PF13481.1 AEO63440.1 - 0.0016 17.9 0.0 0.29 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 AEO63440.1 - 0.002 18.5 1.6 1 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 AEO63440.1 - 0.0026 16.9 1.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 AEO63440.1 - 0.0034 17.5 0.4 1.9 8.6 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 AEO63440.1 - 0.0036 16.7 0.5 2.7 7.3 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_30 PF13604.1 AEO63440.1 - 0.0043 16.6 0.4 2.8 7.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.4 AEO63440.1 - 0.0072 14.9 0.6 0.47 9.0 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.12 AEO63440.1 - 0.013 15.3 3.5 0.11 12.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 AEO63440.1 - 0.015 14.9 0.9 2.5 7.7 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 AEO63440.1 - 0.017 14.0 0.1 0.47 9.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 AEO63440.1 - 0.022 14.5 2.4 0.31 10.8 0.1 2.5 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 AEO63440.1 - 0.026 14.8 1.7 1.1 9.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 AEO63440.1 - 0.027 13.9 0.0 4.4 6.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.1 AEO63440.1 - 0.06 13.3 1.0 0.18 11.7 0.0 2.3 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 AEO63440.1 - 0.064 12.9 0.4 0.54 9.8 0.0 2.3 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.17 AEO63440.1 - 0.11 11.8 0.2 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_15 PF13175.1 AEO63440.1 - 0.13 11.2 0.2 2.9 6.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.12 AEO63440.1 - 0.16 11.4 1.3 9.5 5.6 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.14 AEO63440.1 - 1.1 8.6 3.4 1.4 8.3 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2756 PF10956.3 AEO63441.1 - 0.00021 21.4 2.3 0.00042 20.5 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2756) SpoIIIAH PF12685.2 AEO63441.1 - 0.43 10.0 2.9 0.64 9.4 2.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein AKAP2_C PF15304.1 AEO63441.1 - 2.9 7.4 8.8 0.7 9.4 3.7 1.7 2 0 0 2 2 2 0 A-kinase anchor protein 2 C-terminus Fcf1 PF04900.7 AEO63442.1 - 3.9e-40 136.0 1.2 5.2e-40 135.6 0.2 1.6 2 0 0 2 2 2 1 Fcf1 Glyco_hydro_7 PF00840.15 AEO63442.1 - 0.1 10.9 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 DUF4574 PF15141.1 AEO63442.1 - 0.46 10.2 3.2 0.78 9.5 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4574) NmrA PF05368.8 AEO63443.1 - 5.7e-80 267.9 0.0 7e-80 267.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO63443.1 - 4.9e-06 26.6 0.1 0.00023 21.2 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding DUF2498 PF10692.4 AEO63443.1 - 0.064 12.8 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) ERG2_Sigma1R PF04622.7 AEO63444.1 - 5.8e-96 319.9 0.1 6.5e-96 319.7 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein EXOSC1 PF10447.4 AEO63445.1 - 3.2e-28 97.5 0.8 4.5e-28 97.0 0.5 1.2 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 AEO63445.1 - 7.3e-15 53.9 0.0 1.6e-14 52.8 0.0 1.6 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 AEO63445.1 - 0.021 14.8 0.2 0.16 12.0 0.2 2.0 1 1 0 1 1 1 0 S1 RNA binding domain Sec2p PF06428.6 AEO63446.1 - 7.3e-10 38.5 6.1 7.3e-10 38.5 4.2 2.4 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p SlyX PF04102.7 AEO63446.1 - 0.013 15.8 10.2 0.47 10.8 1.2 3.2 2 2 0 2 2 2 0 SlyX DUF2076 PF09849.4 AEO63446.1 - 0.081 12.9 4.2 0.24 11.4 2.9 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Jnk-SapK_ap_N PF09744.4 AEO63446.1 - 0.17 11.8 9.8 0.87 9.5 0.1 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 BBP1_C PF15272.1 AEO63446.1 - 0.17 11.3 4.9 0.63 9.5 0.1 2.3 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal SSP160 PF06933.6 AEO63446.1 - 0.28 9.1 13.1 0.031 12.2 1.5 2.3 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Laminin_II PF06009.7 AEO63446.1 - 0.28 10.9 6.1 2.5 7.8 0.4 2.3 2 0 0 2 2 2 0 Laminin Domain II MbeD_MobD PF04899.7 AEO63446.1 - 0.32 10.9 9.8 2.7 7.9 0.5 2.9 2 1 0 2 2 2 0 MbeD/MobD like Myosin_tail_1 PF01576.14 AEO63446.1 - 0.55 7.8 20.9 0.38 8.4 8.7 2.1 2 0 0 2 2 2 0 Myosin tail Cluap1 PF10234.4 AEO63446.1 - 0.56 9.3 5.1 0.54 9.4 0.5 2.0 2 0 0 2 2 2 0 Clusterin-associated protein-1 Striatin PF08232.7 AEO63446.1 - 0.6 10.4 8.1 0.73 10.1 0.0 2.5 2 1 0 2 2 2 0 Striatin family Tup_N PF08581.5 AEO63446.1 - 0.6 10.3 5.1 0.25 11.5 0.4 2.3 2 1 0 2 2 2 0 Tup N-terminal EzrA PF06160.7 AEO63446.1 - 0.64 8.1 5.2 0.25 9.4 0.1 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Caudo_TAP PF02413.12 AEO63446.1 - 0.66 10.1 4.6 0.36 11.0 0.2 2.4 2 1 0 2 2 2 0 Caudovirales tail fibre assembly protein DUF972 PF06156.8 AEO63446.1 - 1.3 9.3 6.1 0.98 9.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) ADIP PF11559.3 AEO63446.1 - 2.4 8.0 16.7 2.7 7.8 1.3 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 AEO63446.1 - 2.7 7.1 9.1 2.2 7.4 0.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding HR1 PF02185.11 AEO63446.1 - 3.3 7.5 11.1 0.57 9.9 0.9 3.1 2 1 0 2 2 2 0 Hr1 repeat IncA PF04156.9 AEO63446.1 - 3.4 7.2 18.8 5.5 6.5 4.7 2.2 2 0 0 2 2 2 0 IncA protein Atg14 PF10186.4 AEO63446.1 - 3.6 6.4 11.3 2.9 6.7 0.1 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2360 PF10152.4 AEO63446.1 - 3.7 7.8 24.0 0.12 12.6 6.2 2.5 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) TMF_DNA_bd PF12329.3 AEO63446.1 - 4.3 7.2 10.9 1.7 8.5 0.6 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding TruB_N PF01509.13 AEO63447.1 - 3.8e-45 153.6 0.0 7.9e-45 152.6 0.0 1.5 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) DNMT1-RFD PF12047.3 AEO63448.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain Methyltransf_23 PF13489.1 AEO63449.1 - 1.2e-13 51.1 0.0 2.4e-13 50.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO63449.1 - 8.7e-13 48.5 0.1 3.3e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 AEO63449.1 - 1.2e-10 41.1 0.0 0.0001 21.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 AEO63449.1 - 1.6e-10 41.5 0.0 6.5e-10 39.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO63449.1 - 1.7e-10 41.2 0.0 0.00015 22.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain CMAS PF02353.15 AEO63449.1 - 1.2e-08 34.3 0.0 5.3e-08 32.2 0.0 2.0 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 AEO63449.1 - 6.8e-07 29.5 0.0 4e-06 27.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO63449.1 - 4.8e-05 23.3 0.0 0.00016 21.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO63449.1 - 0.0016 17.6 0.0 0.068 12.2 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 AEO63449.1 - 0.052 12.9 0.2 0.3 10.4 0.1 2.0 2 0 0 2 2 2 0 Methyltransferase small domain TehB PF03848.9 AEO63449.1 - 0.058 12.5 0.0 0.097 11.8 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 AEO63449.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain But2 PF09792.4 AEO63450.1 - 0.056 13.1 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin 3 binding protein But2 C-terminal domain Serglycin PF04360.7 AEO63450.1 - 0.069 12.8 0.1 0.088 12.5 0.1 1.4 1 0 0 1 1 1 0 Serglycin Kinesin PF00225.18 AEO63451.1 - 1.2e-110 369.3 0.3 2.1e-110 368.5 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 AEO63451.1 - 5e-47 159.0 0.0 1.2e-46 157.8 0.0 1.7 1 0 0 1 1 1 1 Kinesin protein FHA PF00498.21 AEO63451.1 - 1.2e-06 28.5 0.0 7.8e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.3 AEO63451.1 - 1.6e-06 28.0 0.5 1.6e-06 28.0 0.3 2.8 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.24 AEO63451.1 - 0.021 15.0 0.0 0.11 12.6 0.0 2.3 1 1 0 1 1 1 0 PH domain Peptidase_M1 PF01433.15 AEO63452.1 - 7.9e-74 249.0 0.0 1e-73 248.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 AEO63452.1 - 7.9e-48 161.6 0.0 1.5e-47 160.7 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 AEO63452.1 - 2.7e-17 62.9 0.1 4.8e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 AEO63452.1 - 0.068 13.1 1.7 0.43 10.5 1.2 2.2 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Lipoprotein_5 PF01298.13 AEO63452.1 - 0.25 10.2 0.1 0.37 9.6 0.0 1.1 1 0 0 1 1 1 0 Transferrin binding protein-like solute binding protein Uds1 PF15456.1 AEO63453.1 - 2.4e-35 121.2 10.9 2.4e-35 121.2 7.5 2.0 2 0 0 2 2 2 1 Up-regulated During Septation TBPIP PF07106.8 AEO63453.1 - 0.17 11.3 2.0 0.98 8.9 1.4 2.0 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Wbp11 PF09429.5 AEO63453.1 - 0.54 10.2 5.5 0.13 12.2 0.5 2.3 2 0 0 2 2 2 0 WW domain binding protein 11 TMF_TATA_bd PF12325.3 AEO63453.1 - 0.72 9.5 6.7 1.6 8.4 4.6 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding AT_hook PF02178.14 AEO63454.1 - 0.68 9.7 7.3 1.8 8.5 5.0 1.8 1 0 0 1 1 1 0 AT hook motif CN_hydrolase PF00795.17 AEO63455.1 - 7.8e-32 110.1 0.0 2.4e-31 108.5 0.0 1.7 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Spermine_synth PF01564.12 AEO63456.1 - 1.3e-98 328.8 0.0 1.8e-98 328.4 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 AEO63456.1 - 6.7e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO63456.1 - 0.00043 19.8 0.0 0.00065 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 AEO63456.1 - 0.00045 19.2 0.0 0.0007 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_18 PF12847.2 AEO63456.1 - 0.00071 20.1 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO63456.1 - 0.001 19.5 0.2 0.0034 17.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 AEO63456.1 - 0.056 12.8 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain G-alpha PF00503.15 AEO63457.1 - 9.3e-118 393.2 0.0 1.1e-117 393.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 AEO63457.1 - 3.6e-13 49.1 0.4 3.5e-08 32.8 0.0 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AEO63457.1 - 0.0016 17.6 0.4 0.29 10.2 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 AEO63457.1 - 0.032 13.6 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 AEO63457.1 - 0.035 13.5 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 AEO63457.1 - 0.06 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_hydro_3 PF00933.16 AEO63458.1 - 4.8e-83 278.5 0.0 6.2e-83 278.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO63458.1 - 1.2e-41 142.7 0.0 1.3e-40 139.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO63458.1 - 6.6e-22 77.2 0.1 1.1e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_10 PF00331.15 AEO63459.1 - 2.7e-82 276.3 0.0 3.1e-82 276.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 GATase_2 PF00310.16 AEO63460.1 - 1.5e-20 73.2 0.0 2e-16 59.6 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 AEO63460.1 - 4.5e-16 59.0 0.1 3.3e-15 56.2 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 AEO63460.1 - 3e-15 56.0 0.0 6.6e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 AEO63460.1 - 2.5e-11 43.4 0.1 5e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 AEO63460.1 - 1.4e-06 27.2 0.0 1.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Trehalase PF01204.13 AEO63461.1 - 1.5e-196 654.0 0.0 1.9e-196 653.6 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 AEO63461.1 - 3.1e-15 55.1 0.5 5.3e-15 54.4 0.3 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain F-box PF00646.28 AEO63462.1 - 0.005 16.4 0.9 0.005 16.4 0.6 2.8 3 0 0 3 3 3 1 F-box domain DUF3405 PF11885.3 AEO63463.1 - 1.6e-76 257.6 0.7 2.9e-76 256.6 0.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) ABC2_membrane_3 PF12698.2 AEO63465.1 - 0.024 13.6 0.7 0.024 13.6 0.5 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Polysacc_synt_3 PF13440.1 AEO63465.1 - 0.16 11.3 2.4 0.17 11.3 1.7 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MRP-L20 PF12824.2 AEO63467.1 - 5.8e-57 192.2 2.9 7.7e-57 191.8 2.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Hyccin PF09790.4 AEO63467.1 - 0.052 12.4 0.2 0.077 11.8 0.2 1.3 1 0 0 1 1 1 0 Hyccin FYVE PF01363.16 AEO63468.1 - 0.0057 16.5 7.1 0.0057 16.5 4.9 2.8 3 1 0 3 3 3 1 FYVE zinc finger zf-B_box PF00643.19 AEO63468.1 - 0.76 9.7 11.6 1.7 8.6 1.4 3.1 3 0 0 3 3 3 0 B-box zinc finger Glyco_trans_2_3 PF13632.1 AEO63469.1 - 1.5e-47 161.8 3.1 1.5e-47 161.8 2.2 3.0 2 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AEO63469.1 - 2.3e-07 30.8 0.3 4.1e-06 26.7 0.2 2.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 AEO63469.1 - 2.3e-05 24.1 0.0 0.00038 20.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Acyl-CoA_dh_1 PF00441.19 AEO63470.1 - 4e-18 65.9 0.3 2.4e-08 34.2 0.0 2.7 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 AEO63470.1 - 1.2e-06 27.9 0.4 1.4e-05 24.4 0.3 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 AEO63470.1 - 0.0015 18.7 7.6 0.54 10.5 0.0 3.6 4 0 0 4 4 4 2 Acyl-CoA dehydrogenase, C-terminal domain SNF2_N PF00176.18 AEO63471.1 - 7.2e-55 185.8 0.2 1e-54 185.3 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 AEO63471.1 - 3.2e-26 91.0 2.1 9.6e-26 89.4 1.4 1.9 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 AEO63471.1 - 6.1e-15 54.8 0.0 2.2e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO63471.1 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21_ATP PF08483.6 AEO63472.1 - 0.022 14.4 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding N-terminal ICL PF00463.16 AEO63473.1 - 3.4e-283 939.6 0.1 3.8e-283 939.4 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 AEO63473.1 - 5.6e-12 45.3 0.1 2e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase CaATP_NAI PF12515.3 AEO63475.1 - 0.066 12.7 0.3 0.094 12.2 0.2 1.2 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain p450 PF00067.17 AEO63476.1 - 2.1e-48 165.0 0.0 5.1e-34 117.5 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 Rho_N PF07498.7 AEO63477.1 - 0.0031 17.2 0.3 0.0058 16.3 0.2 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain PhyH PF05721.8 AEO63478.1 - 1.5e-55 188.5 0.0 2.3e-55 187.8 0.0 1.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RRM_1 PF00076.17 AEO63479.1 - 6.8e-38 128.1 1.5 8.9e-18 63.6 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO63479.1 - 5e-29 100.0 3.1 8.5e-15 54.4 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO63479.1 - 2.8e-13 49.4 0.1 1.6e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO63479.1 - 0.00016 21.3 0.1 0.16 11.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RabGAP-TBC PF00566.13 AEO63480.1 - 2.2e-46 158.0 0.0 4e-45 153.9 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain SHNi-TPR PF10516.4 AEO63481.1 - 1.6e-14 52.8 0.3 1.6e-14 52.8 0.2 2.4 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.1 AEO63481.1 - 1e-06 28.5 15.5 5e-05 23.1 0.9 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO63481.1 - 5.1e-06 27.0 1.8 5.1e-06 27.0 1.3 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 AEO63481.1 - 9.5e-05 21.9 11.9 0.00012 21.6 1.3 3.0 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 AEO63481.1 - 0.00016 21.9 0.5 0.00016 21.9 0.4 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 AEO63481.1 - 0.00022 21.3 2.3 0.012 15.7 0.2 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 AEO63481.1 - 0.0073 16.4 1.4 0.17 12.1 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 AEO63481.1 - 0.018 14.8 5.4 0.018 14.8 3.7 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO63481.1 - 0.74 9.5 4.1 4.1 7.1 2.9 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 AEO63481.1 - 5.4 7.0 8.5 0.52 10.3 0.6 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 AEO63481.1 - 5.8 7.0 21.7 0.19 11.7 3.7 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.5 AEO63481.1 - 6.9 6.9 15.4 0.54 10.5 5.2 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Flavoprotein PF02441.14 AEO63482.1 - 8e-43 145.1 0.5 1.2e-42 144.6 0.3 1.2 1 0 0 1 1 1 1 Flavoprotein zf-CCCH PF00642.19 AEO63483.1 - 0.0035 16.9 3.7 0.006 16.2 2.5 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AEO63483.1 - 0.34 10.9 3.8 0.61 10.1 2.6 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Sec1 PF00995.18 AEO63485.1 - 8.4e-152 506.6 0.0 9.8e-152 506.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Chitin_synth_1 PF01644.12 AEO63486.1 - 1.4e-81 272.0 0.7 2.1e-81 271.4 0.5 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 AEO63486.1 - 9.6e-33 111.7 0.0 1.9e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 AEO63486.1 - 9e-23 80.4 4.2 7.7e-18 64.1 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 AEO63486.1 - 2.5e-07 30.6 7.8 2.5e-07 30.6 5.4 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AEO63486.1 - 1.2e-06 28.4 0.0 5.7e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF3602 PF12223.3 AEO63487.1 - 1.1e-16 60.9 7.9 4.9e-14 52.4 1.9 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) FAM163 PF15069.1 AEO63488.1 - 0.014 15.9 0.2 0.016 15.7 0.1 1.1 1 0 0 1 1 1 0 FAM163 family Actin PF00022.14 AEO63489.1 - 5.9e-132 439.8 0.0 6.6e-132 439.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AEO63489.1 - 0.0054 15.3 0.0 0.95 7.9 0.0 2.7 2 1 0 2 2 2 2 MreB/Mbl protein Methyltransf_2 PF00891.13 AEO63490.1 - 2.3e-24 85.9 0.0 3.1e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MarR_2 PF12802.2 AEO63490.1 - 0.037 13.6 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 MarR family GHMP_kinases_N PF00288.21 AEO63493.1 - 1.4e-08 34.6 0.0 9.4e-08 32.0 0.0 2.2 1 1 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AEO63493.1 - 1.4e-06 28.4 0.0 3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Gly-zipper_OmpA PF13436.1 AEO63494.1 - 0.06 13.0 3.6 0.53 9.9 0.0 3.0 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain IFRD PF05004.8 AEO63495.1 - 2.2e-30 105.8 0.5 2.7e-30 105.5 0.4 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 AEO63495.1 - 7.6e-05 22.9 0.4 0.034 14.4 0.3 2.4 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 AEO63495.1 - 0.00013 22.3 0.5 11 6.6 0.1 4.5 2 1 4 6 6 6 1 HEAT-like repeat NAF PF03822.9 AEO63495.1 - 0.11 12.2 0.1 0.28 10.9 0.1 1.7 1 0 0 1 1 1 0 NAF domain Corona_nucleoca PF00937.13 AEO63495.1 - 0.46 9.3 4.5 0.78 8.6 3.1 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein FHA PF00498.21 AEO63496.1 - 9.7e-13 48.0 0.0 2.1e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain WD40 PF00400.27 AEO63497.1 - 2.5e-48 160.2 14.9 1.2e-10 40.8 0.0 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 AEO63497.1 - 5.9e-09 34.6 2.3 0.021 12.9 0.1 4.9 2 1 2 5 5 5 4 Nucleoporin Nup120/160 DUF1513 PF07433.6 AEO63497.1 - 0.00066 18.6 0.2 3.1 6.5 0.0 3.6 1 1 3 4 4 4 3 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.6 AEO63497.1 - 0.12 11.0 0.1 2 7.0 0.0 2.7 1 1 1 2 2 2 0 Nup133 N terminal like HEAT PF02985.17 AEO63498.1 - 9.2e-11 40.8 6.1 0.021 14.8 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat Pkinase PF00069.20 AEO63498.1 - 8.6e-08 31.6 0.0 1.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 AEO63498.1 - 4.6e-05 22.5 0.0 7.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 AEO63498.1 - 8.9e-05 21.6 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 AEO63498.1 - 0.00027 21.1 0.1 0.048 13.9 0.0 3.6 2 1 2 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 AEO63498.1 - 0.00068 20.0 0.0 0.46 11.0 0.0 3.4 2 0 0 2 2 2 1 HEAT-like repeat Adaptin_N PF01602.15 AEO63498.1 - 0.0051 15.2 0.1 0.0084 14.4 0.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region FTA2 PF13095.1 AEO63500.1 - 1.5e-42 145.5 0.0 2e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Aconitase PF00330.15 AEO63502.1 - 1.4e-151 505.1 0.0 3.9e-151 503.6 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AEO63502.1 - 2.2e-35 121.6 0.0 3.6e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Rad52_Rad22 PF04098.10 AEO63503.1 - 7.1e-61 204.4 0.0 1e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Cut8_C PF08559.5 AEO63504.1 - 1.5e-48 164.2 0.0 1.9e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 AEO63504.1 - 4.6e-16 58.3 0.3 9.6e-16 57.3 0.2 1.6 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 AEO63504.1 - 9.3e-09 35.1 1.3 1.7e-08 34.2 0.9 1.5 1 0 0 1 1 1 1 Cut8 proteasome-binding domain HTH_OrfB_IS605 PF12323.3 AEO63505.1 - 0.074 12.3 0.3 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PDDEXK_3 PF13366.1 AEO63505.1 - 0.15 12.1 1.0 0.18 11.8 0.7 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily RRM_1 PF00076.17 AEO63506.1 - 1.4e-23 82.2 0.0 1.4e-13 50.2 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO63506.1 - 2.1e-19 69.2 0.0 1.6e-08 34.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO63506.1 - 1.7e-06 27.7 0.0 0.013 15.3 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4611 PF15387.1 AEO63506.1 - 0.021 14.9 2.5 0.021 14.9 1.8 2.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) RRM_3 PF08777.6 AEO63506.1 - 0.17 11.7 0.0 0.17 11.7 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif ZZ PF00569.12 AEO63507.1 - 7.9e-17 60.5 56.4 8.3e-07 28.4 2.1 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type UPF0052 PF01933.13 AEO63508.1 - 1.2e-29 103.6 0.0 1.5e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Btz PF09405.5 AEO63509.1 - 1.9e-27 95.8 1.4 5e-27 94.5 0.9 1.7 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Asp PF00026.18 AEO63510.1 - 2.7e-59 200.9 2.6 5.2e-59 200.0 1.8 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Aminotran_4 PF01063.14 AEO63510.1 - 8.7e-14 51.5 0.0 1.8e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class IV TAXi_N PF14543.1 AEO63510.1 - 7.4e-08 32.5 0.5 5.2e-07 29.7 0.4 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO63510.1 - 1.2e-06 28.8 0.1 0.0012 19.2 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease NKWYS PF10364.4 AEO63510.1 - 0.05 13.3 0.1 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Putative capsular polysaccharide synthesis protein TPR_11 PF13414.1 AEO63511.1 - 6.5e-52 173.0 29.2 8.8e-15 54.1 1.3 6.6 4 2 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 AEO63511.1 - 6e-44 145.9 32.2 5.6e-06 25.7 0.1 11.4 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 AEO63511.1 - 1.3e-38 127.7 30.9 6.7e-05 22.5 0.0 11.5 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.1 AEO63511.1 - 5.8e-25 87.3 22.9 9e-06 26.2 1.9 7.0 6 1 1 7 7 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 AEO63511.1 - 5e-23 80.8 27.0 1e-06 28.5 0.7 7.4 2 2 5 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 AEO63511.1 - 2.2e-21 74.1 15.0 0.0016 18.4 0.5 8.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 AEO63511.1 - 1.3e-13 49.6 24.1 0.015 15.0 0.1 10.5 10 1 1 11 11 10 2 Tetratricopeptide repeat TPR_9 PF13371.1 AEO63511.1 - 8.4e-13 47.9 9.7 2.8e-05 23.8 0.4 6.0 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 AEO63511.1 - 1.6e-12 46.9 20.6 0.035 14.7 0.6 10.1 3 3 8 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 AEO63511.1 - 3.9e-11 43.1 23.9 1.3e-06 28.6 0.6 6.7 5 1 1 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 AEO63511.1 - 3e-09 36.8 19.7 0.00045 20.2 0.2 6.0 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 AEO63511.1 - 3.8e-08 32.5 22.8 0.041 13.6 0.2 9.0 9 1 1 10 10 10 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 AEO63511.1 - 6.6e-06 25.2 7.4 0.41 9.9 0.0 6.2 6 0 0 6 6 6 2 SHNi-TPR TPR_10 PF13374.1 AEO63511.1 - 0.0018 18.1 8.4 1.6 8.7 0.5 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat Med3 PF11593.3 AEO63511.1 - 0.011 15.0 5.6 0.023 13.9 3.7 1.6 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal TPR_6 PF13174.1 AEO63511.1 - 0.022 15.1 22.8 2.2 8.9 0.0 8.9 10 0 0 10 10 10 0 Tetratricopeptide repeat DUF3856 PF12968.2 AEO63511.1 - 0.3 10.9 11.0 4.2 7.1 0.0 4.7 5 2 0 5 5 4 0 Domain of Unknown Function (DUF3856) DALR_1 PF05746.10 AEO63511.1 - 0.44 10.5 4.5 0.44 10.5 0.5 2.7 2 0 0 2 2 2 0 DALR anticodon binding domain Sel1 PF08238.7 AEO63511.1 - 0.54 10.9 7.8 1.8 9.3 0.2 3.8 3 0 0 3 3 3 0 Sel1 repeat MAS20 PF02064.10 AEO63511.1 - 0.92 9.4 8.6 17 5.3 0.0 4.6 5 1 0 5 5 4 0 MAS20 protein import receptor LTXXQ PF07813.7 AEO63511.1 - 6.1 7.3 14.7 3.9 7.9 7.1 2.7 2 1 0 2 2 2 0 LTXXQ motif family protein Syntaxin PF00804.20 AEO63512.1 - 1e-10 41.6 7.6 1e-10 41.6 5.2 2.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 AEO63512.1 - 3.2e-08 33.1 8.4 3.2e-08 33.1 5.8 2.6 4 0 0 4 4 3 1 SNARE domain Bac_export_3 PF01313.14 AEO63512.1 - 0.047 13.3 0.2 0.13 11.9 0.2 1.7 1 0 0 1 1 1 0 Bacterial export proteins, family 3 DUF3018 PF11455.3 AEO63512.1 - 0.06 13.2 0.2 0.06 13.2 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3018) FlaC_arch PF05377.6 AEO63512.1 - 0.085 12.7 3.2 25 4.8 0.0 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) MCPsignal PF00015.16 AEO63512.1 - 0.14 11.6 11.6 0.067 12.7 1.7 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3753 PF12575.3 AEO63512.1 - 0.18 11.6 0.7 6.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Synaptobrevin PF00957.16 AEO63512.1 - 0.23 11.1 7.0 0.034 13.7 0.9 2.6 2 1 1 3 3 3 0 Synaptobrevin FAA_hydrolase_N PF09298.6 AEO63512.1 - 0.59 10.1 9.0 0.71 9.9 1.2 2.8 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal DUF4094 PF13334.1 AEO63512.1 - 0.69 10.3 4.2 4.2 7.8 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4094) DUF1469 PF07332.6 AEO63512.1 - 0.96 9.1 4.1 0.5 10.1 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) SlyX PF04102.7 AEO63512.1 - 1.3 9.4 14.6 1.5 9.2 3.6 3.3 2 2 1 3 3 3 0 SlyX Med9 PF07544.8 AEO63512.1 - 2.7 7.7 11.4 9.7 6.0 0.1 3.4 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Laminin_II PF06009.7 AEO63512.1 - 5.5 6.7 13.7 0.18 11.5 1.2 2.9 2 1 1 3 3 3 0 Laminin Domain II Brix PF04427.13 AEO63513.1 - 2e-45 154.8 0.5 2.6e-45 154.4 0.3 1.1 1 0 0 1 1 1 1 Brix domain UPF1_Zn_bind PF09416.5 AEO63515.1 - 9.6e-71 236.3 2.7 1.6e-70 235.5 1.9 1.4 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) zf-HIT PF04438.11 AEO63515.1 - 0.6 9.7 4.2 1.3 8.7 2.9 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-UBP PF02148.14 AEO63515.1 - 1.9 8.6 7.0 4.7 7.4 4.9 1.7 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-BED PF02892.10 AEO63515.1 - 2.6 7.8 5.3 10 5.9 3.7 2.0 1 1 0 1 1 1 0 BED zinc finger AhpC-TSA_2 PF13911.1 AEO63516.1 - 5.1e-18 65.0 0.0 1.4e-17 63.6 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 AEO63516.1 - 0.00079 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AEO63516.1 - 0.076 12.5 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 Redoxin TFIIA PF03153.8 AEO63518.1 - 0.012 15.5 8.4 0.016 15.0 5.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aminotran_4 PF01063.14 AEO63519.1 - 1.6e-23 83.3 0.0 2.4e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV DEK_C PF08766.6 AEO63519.1 - 0.051 13.3 0.1 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 DEK C terminal domain CTP_transf_2 PF01467.21 AEO63523.1 - 3.4e-18 66.1 0.0 3.8e-15 56.2 0.0 3.2 2 1 0 2 2 2 2 Cytidylyltransferase WD40 PF00400.27 AEO63524.1 - 9.8e-26 88.6 0.2 0.00019 21.1 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat AAT PF03417.11 AEO63526.1 - 5.1e-12 45.7 0.0 8.9e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase ABC1 PF03109.11 AEO63527.1 - 4.1e-31 107.4 0.0 6.8e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family 2OG-FeII_Oxy_3 PF13640.1 AEO63528.1 - 6.7e-07 29.7 0.0 8.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_76 PF03663.9 AEO63530.1 - 3.9e-153 510.2 14.0 5.1e-153 509.8 9.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 AEO63530.1 - 0.0089 15.1 9.6 0.13 11.2 0.1 3.1 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 Gln-synt_C PF00120.19 AEO63531.1 - 4.9e-56 189.7 0.0 7.5e-56 189.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 AEO63531.1 - 4.3e-28 98.6 0.4 1.2e-27 97.1 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase MR_MLE_C PF13378.1 AEO63531.1 - 0.065 13.2 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 Enolase C-terminal domain-like COPIIcoated_ERV PF07970.7 AEO63532.1 - 1.8e-33 116.0 0.0 2.4e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 AEO63532.1 - 4.4e-20 71.4 0.0 6.9e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CAP_N PF01213.14 AEO63533.1 - 0.023 13.9 0.6 0.02 14.1 0.4 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA_17 PF13207.1 AEO63535.1 - 1.7e-06 28.8 0.0 3.5e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO63535.1 - 4.4e-05 23.7 0.0 6.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain PRK PF00485.13 AEO63535.1 - 9.3e-05 22.0 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 AEO63535.1 - 0.00096 18.3 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 AEO63535.1 - 0.0016 18.3 0.4 0.0033 17.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 AEO63535.1 - 0.0049 15.6 0.0 0.0065 15.2 0.0 1.1 1 0 0 1 1 1 1 ArgK protein KTI12 PF08433.5 AEO63535.1 - 0.014 14.6 0.0 0.034 13.3 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NB-ARC PF00931.17 AEO63535.1 - 0.02 13.7 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 AEO63535.1 - 0.027 14.4 0.2 0.054 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 AEO63535.1 - 0.029 13.8 0.1 0.041 13.3 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 AEO63535.1 - 0.03 14.4 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 AEO63535.1 - 0.034 13.9 0.4 0.075 12.7 0.3 1.8 1 1 0 1 1 1 0 Part of AAA domain KAP_NTPase PF07693.9 AEO63535.1 - 0.035 13.0 0.0 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.7 AEO63535.1 - 0.044 13.4 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 AEO63535.1 - 0.063 13.0 0.1 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 AEO63535.1 - 0.066 12.9 0.1 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 NTPase Thymidylate_kin PF02223.12 AEO63535.1 - 0.071 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase AAA_25 PF13481.1 AEO63535.1 - 0.1 12.0 0.2 0.17 11.3 0.2 1.5 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 AEO63535.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.1 AEO63535.1 - 0.14 12.1 0.1 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 AEO63535.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase 6PF2K PF01591.13 AEO63535.1 - 0.17 10.9 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Glyco_hydro_9 PF00759.14 AEO63536.1 - 0.18 10.6 3.8 0.26 10.1 2.6 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 TALPID3 PF15324.1 AEO63536.1 - 9.1 3.4 8.4 13 2.9 5.8 1.1 1 0 0 1 1 1 0 Hedgehog signalling target PRELI PF04707.9 AEO63537.1 - 4.1e-43 146.6 0.2 5.1e-43 146.3 0.1 1.1 1 0 0 1 1 1 1 PRELI-like family GATase_3 PF07685.9 AEO63537.1 - 0.0072 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_M24 PF00557.19 AEO63538.1 - 5e-46 156.8 0.1 7.2e-46 156.3 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Med3 PF11593.3 AEO63538.1 - 0.0025 17.0 0.7 0.0036 16.6 0.5 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal DUF3292 PF11696.3 AEO63538.1 - 3.5 5.3 6.2 4.9 4.8 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DnaJ PF00226.26 AEO63539.1 - 7.5e-13 48.0 0.2 1.1e-12 47.4 0.2 1.2 1 0 0 1 1 1 1 DnaJ domain SMN PF06003.7 AEO63539.1 - 8.2 5.4 7.9 13 4.7 5.5 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Porin_3 PF01459.17 AEO63540.1 - 2.7e-66 223.6 7.6 3e-66 223.5 5.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin OMP_b-brl PF13505.1 AEO63540.1 - 1.6 8.6 11.6 0.31 10.9 5.0 1.9 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain Asn_synthase PF00733.16 AEO63541.1 - 7.4e-69 232.0 0.0 1e-68 231.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 AEO63541.1 - 1.7e-36 124.6 0.0 2.7e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 AEO63541.1 - 1.9e-28 99.0 0.0 5.6e-28 97.5 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 AEO63541.1 - 2.2e-08 33.6 0.0 3.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 AEO63541.1 - 0.00044 19.2 0.1 0.0017 17.2 0.0 1.8 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 AEO63541.1 - 0.0013 17.5 0.0 0.071 11.7 0.0 2.7 1 1 2 3 3 3 1 Glutamine amidotransferases class-II QueC PF06508.8 AEO63541.1 - 0.19 11.0 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC UQ_con PF00179.21 AEO63542.1 - 5.1e-49 165.3 0.1 5.7e-49 165.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO63542.1 - 0.00021 21.0 0.0 0.00029 20.6 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AEO63542.1 - 0.056 13.3 2.4 0.16 11.8 1.7 1.9 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.7 AEO63543.1 - 4e-73 246.1 10.0 4e-73 246.1 7.0 1.5 2 0 0 2 2 2 1 Pex19 protein family Glyco_transf_15 PF01793.11 AEO63543.1 - 0.1 11.5 0.2 0.16 10.8 0.2 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Gluconate_2-dh3 PF13618.1 AEO63543.1 - 0.11 12.6 4.8 0.27 11.3 0.8 2.7 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 FliE PF02049.13 AEO63543.1 - 0.12 12.3 3.4 1.5 8.9 0.2 3.4 2 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE DUF1104 PF06518.6 AEO63543.1 - 1.8 8.7 8.6 1.1 9.4 0.4 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1104) Period_C PF12114.3 AEO63544.1 - 0.098 12.2 0.9 0.13 11.8 0.7 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Formyl_trans_N PF00551.14 AEO63546.1 - 7.6e-12 45.1 0.0 1.3e-11 44.4 0.0 1.3 1 1 0 1 1 1 1 Formyl transferase CIAPIN1 PF05093.8 AEO63548.1 - 6.3e-35 119.2 5.2 1e-34 118.6 3.6 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Peptidase_S10 PF00450.17 AEO63549.1 - 1.8e-113 379.8 0.0 2.3e-113 379.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 AEO63549.1 - 0.0018 18.1 0.0 0.014 15.2 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family RNA_Me_trans PF04252.8 AEO63550.1 - 6.9e-49 165.9 0.0 8e-49 165.7 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DHO_dh PF01180.16 AEO63551.1 - 4.1e-20 71.9 0.0 6e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase DHquinase_I PF01487.10 AEO63552.1 - 2.5e-58 197.4 0.0 3.3e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fungal_trans PF04082.13 AEO63553.1 - 9.9e-28 96.7 0.0 1.7e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO63553.1 - 5.7e-06 26.1 15.4 9.8e-06 25.3 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 AEO63555.1 - 2e-29 102.4 59.1 2.9e-29 101.8 41.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO63555.1 - 1.3e-08 33.9 14.9 1.3e-08 33.9 10.3 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter CDC37_N PF03234.9 AEO63556.1 - 2.5e-51 174.4 5.1 2.5e-51 174.4 3.5 1.8 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 AEO63556.1 - 2.4e-23 82.5 0.1 7.7e-23 80.8 0.0 1.9 1 1 1 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 AEO63556.1 - 6.4e-23 80.4 1.1 6.4e-23 80.4 0.8 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain DUF4613 PF15390.1 AEO63556.1 - 0.059 11.5 4.1 0.091 10.9 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) HTH_45 PF14947.1 AEO63556.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DUF4407 PF14362.1 AEO63556.1 - 2.3 7.1 9.0 7.5 5.4 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) YicC_N PF03755.8 AEO63556.1 - 2.4 8.0 9.6 11 5.8 0.1 3.5 3 1 0 3 3 3 0 YicC-like family, N-terminal region Amidohydro_2 PF04909.9 AEO63557.1 - 2.1e-09 37.3 0.6 6.3e-09 35.7 0.4 1.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 AEO63557.1 - 2.3e-08 34.4 4.9 3.1e-08 34.0 3.4 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 AEO63557.1 - 3.7e-05 23.5 0.1 4.4e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Spc97_Spc98 PF04130.8 AEO63558.1 - 8.5e-119 397.3 0.3 2.9e-118 395.5 0.1 1.8 2 0 0 2 2 2 1 Spc97 / Spc98 family Flg_hook PF02120.11 AEO63558.1 - 0.02 14.5 1.3 0.052 13.2 0.1 2.2 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK SAGA-Tad1 PF12767.2 AEO63559.1 - 7e-61 206.0 0.0 2.7e-60 204.1 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit MRC1 PF09444.5 AEO63560.1 - 1.1e-15 58.2 13.0 1.1e-15 58.2 9.0 7.2 6 2 2 8 8 8 2 MRC1-like domain Pkinase PF00069.20 AEO63561.1 - 3.8e-42 144.2 0.0 2.5e-41 141.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO63561.1 - 5.6e-21 74.7 0.0 1.2e-20 73.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Med1 PF10744.4 AEO63562.1 - 1.9e-33 115.8 0.0 3.3e-32 111.7 0.0 2.1 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 FlgN PF05130.7 AEO63563.1 - 0.017 15.3 4.3 0.017 15.3 3.0 3.0 2 1 1 3 3 3 0 FlgN protein Umbravirus_LDM PF04817.7 AEO63563.1 - 0.073 12.1 0.1 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family CDKN3 PF05706.7 AEO63563.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DivIVA PF05103.8 AEO63563.1 - 0.21 11.6 6.1 0.5 10.4 0.4 2.5 1 1 0 2 2 2 0 DivIVA protein Sipho_Gp157 PF05565.6 AEO63563.1 - 0.28 10.7 7.1 0.96 9.0 0.1 2.7 2 1 1 3 3 3 0 Siphovirus Gp157 YicC_N PF03755.8 AEO63563.1 - 0.33 10.8 12.3 0.57 10.1 2.0 2.6 1 1 2 3 3 3 0 YicC-like family, N-terminal region CENP-Q PF13094.1 AEO63563.1 - 0.8 9.7 11.8 0.41 10.6 4.2 2.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CorA PF01544.13 AEO63563.1 - 5.9 5.8 6.0 0.81 8.6 0.7 2.1 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein PV-1 PF06637.6 AEO63563.1 - 7.1 5.0 17.1 0.37 9.2 6.4 2.0 1 1 1 2 2 2 0 PV-1 protein (PLVAP) LRR_6 PF13516.1 AEO63564.1 - 6.7e-06 25.6 7.1 4.1 7.7 0.0 7.7 8 1 0 8 8 8 1 Leucine Rich repeat LRR_4 PF12799.2 AEO63564.1 - 0.00027 20.4 3.0 0.19 11.3 0.1 4.6 6 0 0 6 6 6 1 Leucine Rich repeats (2 copies) YqzE PF14038.1 AEO63564.1 - 2.3 8.0 5.1 93 2.8 3.3 2.8 2 0 0 2 2 2 0 YqzE-like protein Ribosomal_L18p PF00861.17 AEO63565.1 - 2e-42 144.1 0.1 2e-42 144.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 AEO63565.1 - 4.6e-34 116.8 8.2 4.6e-34 116.8 5.7 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region HAD_2 PF13419.1 AEO63566.1 - 2.8e-12 47.2 0.1 2.7e-11 44.0 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO63566.1 - 6.8e-05 22.5 0.1 0.00035 20.2 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like MCM PF00493.18 AEO63567.1 - 8.1e-141 468.5 0.1 8.1e-141 468.5 0.1 1.6 2 0 0 2 2 2 1 MCM2/3/5 family MCM2_N PF12619.3 AEO63567.1 - 1.5e-31 109.5 39.1 1.5e-31 109.5 27.1 2.4 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 AEO63567.1 - 7.9e-21 74.7 0.1 1.9e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 AEO63567.1 - 9.6e-08 31.4 0.0 5.4e-06 25.7 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AEO63567.1 - 5.3e-06 26.1 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AEO63567.1 - 0.0012 18.4 0.0 0.017 14.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AEO63567.1 - 0.0012 18.2 0.2 0.0081 15.6 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain zf-TFIIB PF13453.1 AEO63567.1 - 0.18 11.0 1.2 0.41 9.8 0.8 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-UBR PF02207.15 AEO63568.1 - 6.6e-16 57.7 4.9 6.6e-16 57.7 3.4 2.8 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) ATG2_CAD PF13329.1 AEO63569.1 - 1.6e-46 157.7 0.0 3.5e-46 156.6 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 AEO63569.1 - 5.8e-30 103.3 0.3 1.7e-29 101.8 0.2 1.9 1 0 0 1 1 1 1 ATG C terminal domain Amino_oxidase PF01593.19 AEO63570.1 - 6.3e-52 177.1 1.6 8.7e-51 173.3 1.1 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 AEO63570.1 - 7.1e-17 61.1 0.2 1.9e-16 59.8 0.0 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 AEO63570.1 - 6.1e-08 32.5 0.6 0.00013 21.7 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 AEO63570.1 - 3.2e-07 29.6 0.0 0.00011 21.2 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO63570.1 - 4.3e-06 27.0 0.3 3.6e-05 24.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO63570.1 - 8.8e-06 25.9 0.1 0.00048 20.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO63570.1 - 2.1e-05 23.1 0.1 0.0021 16.5 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 AEO63570.1 - 9.8e-05 21.5 0.0 0.00085 18.4 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 AEO63570.1 - 0.00017 20.7 0.2 0.00027 20.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 AEO63570.1 - 0.0004 19.3 0.4 0.0011 17.8 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 AEO63570.1 - 0.00045 20.1 0.0 0.0058 16.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 AEO63570.1 - 0.005 16.5 0.1 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 AEO63570.1 - 0.019 14.0 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Rossmann-like PF10727.4 AEO63570.1 - 0.042 13.5 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain Lycopene_cycl PF05834.7 AEO63570.1 - 0.062 12.1 0.1 0.5 9.2 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 AEO63570.1 - 0.11 11.8 0.6 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Acyl-CoA_dh_1 PF00441.19 AEO63571.1 - 2.3e-35 121.9 3.8 3.5e-35 121.3 2.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 AEO63571.1 - 7.9e-21 73.6 0.6 1.7e-20 72.6 0.1 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 AEO63571.1 - 1.3e-16 59.8 0.7 3.2e-16 58.5 0.5 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 AEO63571.1 - 2.3e-07 31.3 0.2 7.8e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 AEO63571.1 - 5.1e-05 23.5 0.5 0.00012 22.2 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 AEO63571.1 - 0.089 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal zf-CCHC PF00098.18 AEO63572.1 - 3.3e-12 45.6 19.4 2e-08 33.7 3.0 3.5 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_6 PF15288.1 AEO63572.1 - 0.0015 18.1 9.5 0.046 13.3 1.9 2.8 2 1 1 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.1 AEO63572.1 - 0.0031 17.1 5.4 0.26 10.9 0.6 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 AEO63572.1 - 0.37 10.5 9.7 0.3 10.8 0.7 2.5 3 0 0 3 3 3 0 Zinc knuckle IBR PF01485.16 AEO63572.1 - 0.43 10.4 4.0 1.7 8.6 1.2 2.2 2 0 0 2 2 2 0 IBR domain DnaJ_CXXCXGXG PF00684.14 AEO63572.1 - 0.68 10.0 11.4 1.8 8.6 2.3 2.4 1 1 0 1 1 1 0 DnaJ central domain Hormone_4 PF00220.12 AEO63572.1 - 0.73 9.6 0.2 0.73 9.6 0.2 3.0 4 1 0 3 3 3 0 Neurohypophysial hormones, N-terminal Domain GRP PF07172.6 AEO63572.1 - 6.8 7.2 11.8 9.4 6.7 8.2 1.2 1 0 0 1 1 1 0 Glycine rich protein family SAE2 PF08573.5 AEO63573.1 - 3.6e-28 98.1 0.0 2.5e-27 95.3 0.0 2.4 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Uds1 PF15456.1 AEO63573.1 - 0.084 12.8 3.5 5.6 6.9 0.4 2.5 2 0 0 2 2 2 0 Up-regulated During Septation TPR_MLP1_2 PF07926.7 AEO63573.1 - 0.34 10.6 3.4 0.35 10.6 0.5 2.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein UCH PF00443.24 AEO63574.1 - 1.4e-49 168.6 0.0 5.1e-49 166.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO63574.1 - 2.5e-17 63.2 0.0 2.4e-16 60.0 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Glyco_transf_8 PF01501.15 AEO63575.1 - 7.4e-22 77.8 0.0 5.1e-11 42.3 0.0 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 8 RNase_T PF00929.19 AEO63576.1 - 3.9e-07 30.4 0.0 0.025 14.8 0.0 2.3 2 0 0 2 2 2 2 Exonuclease CHORD PF04968.7 AEO63576.1 - 6.5 7.0 7.2 0.44 10.8 0.2 2.4 2 1 1 3 3 3 0 CHORD Band_7 PF01145.20 AEO63577.1 - 2.9e-24 85.9 7.1 3.1e-24 85.8 4.2 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 AEO63577.1 - 0.0042 16.5 1.3 0.0069 15.7 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) YdfA_immunity PF12127.3 AEO63577.1 - 0.006 15.5 4.6 0.0085 15.0 3.2 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial UcrQ PF02939.11 AEO63578.1 - 6.8e-33 112.3 0.2 8.2e-33 112.0 0.1 1.1 1 0 0 1 1 1 1 UcrQ family NIF PF03031.13 AEO63579.1 - 1.8e-51 173.9 0.0 2.5e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Calici_coat PF00915.15 AEO63579.1 - 0.098 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Calicivirus coat protein DUF1761 PF08570.5 AEO63581.1 - 7.4e-21 74.4 4.4 8.6e-21 74.2 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Ribosomal_L7Ae PF01248.21 AEO63582.1 - 1.1e-15 56.8 2.2 7.2e-15 54.2 0.3 2.8 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Dsh_C PF12316.3 AEO63582.1 - 8.5 6.4 6.3 9.2 6.3 0.1 2.2 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal IF-2B PF01008.12 AEO63583.1 - 1.8e-40 138.7 0.0 7.7e-40 136.6 0.0 1.8 1 1 0 1 1 1 1 Initiation factor 2 subunit family Cep57_MT_bd PF06657.8 AEO63583.1 - 0.098 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF4646 PF15496.1 AEO63584.1 - 2.3e-08 34.1 0.3 5.2e-07 29.7 0.2 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) IncA PF04156.9 AEO63584.1 - 2.8 7.5 23.0 0.43 10.1 4.4 2.4 2 0 0 2 2 2 0 IncA protein Acetyltransf_1 PF00583.19 AEO63585.1 - 1.5e-14 53.7 0.1 2.6e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 AEO63585.1 - 1.7e-06 27.6 0.1 3.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 AEO63585.1 - 0.0011 19.0 0.1 0.0029 17.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO63585.1 - 0.0068 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO63585.1 - 0.024 14.4 0.1 0.043 13.6 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short PF00106.20 AEO63586.1 - 8.7e-33 113.5 2.7 1.4e-32 112.9 1.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO63586.1 - 1.9e-21 76.9 0.1 1.1e-20 74.5 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO63586.1 - 8.4e-17 61.4 0.7 1.2e-16 60.8 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO63586.1 - 1.5e-08 34.4 0.1 4.4e-08 32.8 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Yae1_N PF09811.4 AEO63587.1 - 1e-08 34.5 8.7 2e-08 33.6 6.0 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Trns_repr_metal PF02583.12 AEO63587.1 - 0.19 11.9 0.8 0.49 10.6 0.5 1.7 1 1 0 1 1 1 0 Metal-sensitive transcriptional repressor RVT_1 PF00078.22 AEO63589.1 - 0.00012 21.5 0.5 0.00015 21.1 0.3 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AhpC-TSA PF00578.16 AEO63590.1 - 5.9e-24 84.1 0.0 9.4e-24 83.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AEO63590.1 - 1.2e-16 60.5 0.0 1.8e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 AEO63590.1 - 0.00058 19.7 0.0 0.0011 18.8 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Mito_carr PF00153.22 AEO63591.1 - 1.9e-72 239.0 0.0 2.9e-25 87.7 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.11 AEO63592.1 - 4.5e-47 158.1 0.5 5.2e-47 157.9 0.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Anp1 PF03452.9 AEO63593.1 - 7.4e-109 363.0 0.0 8.9e-109 362.7 0.0 1.1 1 0 0 1 1 1 1 Anp1 HhH-GPD PF00730.20 AEO63594.1 - 5.7e-16 58.7 0.0 1.9e-15 57.0 0.0 1.9 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Ecm33 PF12454.3 AEO63595.1 - 5.4e-14 51.7 0.7 5.4e-14 51.7 0.5 2.8 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 AEO63595.1 - 8.5e-08 32.1 8.5 0.0055 16.6 0.0 4.1 1 1 3 4 4 4 2 Receptor L domain LRR_5 PF13306.1 AEO63595.1 - 0.00031 20.4 9.5 0.025 14.2 0.1 2.4 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) G-patch PF01585.18 AEO63597.1 - 7.8e-11 41.5 0.4 7.8e-11 41.5 0.3 1.9 2 0 0 2 2 2 1 G-patch domain RRM_5 PF13893.1 AEO63597.1 - 0.0035 17.1 0.0 0.03 14.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HA2 PF04408.18 AEO63599.1 - 2.3e-24 85.3 0.0 5.2e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AEO63599.1 - 6.1e-22 77.5 0.0 1.2e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AEO63599.1 - 8.2e-12 44.8 0.0 2e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AEO63599.1 - 4.4e-05 23.0 0.1 9.4e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AEO63599.1 - 8.2e-05 22.7 0.0 0.0002 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 AEO63599.1 - 0.0025 16.7 0.0 0.0054 15.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 AEO63599.1 - 0.012 15.1 0.1 0.022 14.1 0.1 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain cobW PF02492.14 AEO63599.1 - 0.023 14.1 0.1 0.77 9.1 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 AEO63599.1 - 0.051 13.3 0.1 0.85 9.4 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_11 PF13086.1 AEO63599.1 - 1.3 8.5 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 AEO63599.1 - 3.1 8.0 0.0 3.1 8.0 0.0 2.8 2 1 0 2 2 1 0 AAA domain AMP-binding PF00501.23 AEO63600.1 - 3.8e-88 295.6 0.0 4.6e-88 295.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO63600.1 - 2.4e-17 63.6 0.2 7.1e-17 62.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 AEO63600.1 - 0.002 16.7 0.0 0.019 13.4 0.0 2.0 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Motile_Sperm PF00635.21 AEO63601.1 - 2.6e-23 81.7 0.2 4.4e-23 80.9 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Abhydrolase_5 PF12695.2 AEO63602.1 - 2.2e-12 46.9 0.1 3.4e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO63602.1 - 1.4e-11 44.7 4.2 2.8e-11 43.7 2.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 AEO63602.1 - 6.6e-07 29.1 0.2 1.2e-06 28.3 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AEO63602.1 - 0.0014 17.9 0.1 0.015 14.5 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 AEO63602.1 - 0.012 15.1 0.1 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 AEO63602.1 - 0.018 14.8 0.0 0.052 13.3 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 AEO63602.1 - 0.024 14.0 0.1 0.36 10.2 0.0 2.5 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase UBA PF00627.26 AEO63603.1 - 0.00018 21.2 0.1 0.00061 19.5 0.1 2.0 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.15 AEO63603.1 - 0.023 14.7 0.1 0.079 13.0 0.0 2.0 2 0 0 2 2 2 0 UBX domain zf-C2H2 PF00096.21 AEO63603.1 - 0.14 12.6 1.1 0.28 11.6 0.8 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type SOBP PF15279.1 AEO63603.1 - 0.33 11.2 5.9 0.38 11.0 4.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CAF-1_p150 PF11600.3 AEO63603.1 - 0.55 9.5 39.3 0.81 9.0 27.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC27 PF09507.5 AEO63603.1 - 0.6 9.2 24.4 0.73 8.9 16.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DIT1_PvcA PF05141.7 AEO63603.1 - 8.7 5.5 9.5 13 5.0 6.6 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein YCII PF03795.9 AEO63604.1 - 1.5e-08 34.6 0.0 2e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain DUF2408 PF10303.4 AEO63605.1 - 6.9e-52 175.1 11.0 7.4e-32 110.2 0.4 5.0 3 2 1 5 5 5 4 Protein of unknown function (DUF2408) MitMem_reg PF13012.1 AEO63605.1 - 0.035 14.1 4.6 1.9 8.6 0.1 3.0 1 1 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF1664 PF07889.7 AEO63605.1 - 0.076 12.8 4.4 1.9 8.2 0.8 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) CARD PF00619.16 AEO63605.1 - 0.14 12.0 4.1 0.13 12.1 0.6 2.5 2 1 0 2 2 2 0 Caspase recruitment domain Nnf1 PF03980.9 AEO63605.1 - 0.86 9.6 7.0 0.19 11.7 1.0 2.8 2 1 1 3 3 3 0 Nnf1 Laminin_II PF06009.7 AEO63605.1 - 1.7 8.3 5.5 1.7 8.3 1.3 2.6 2 1 0 2 2 2 0 Laminin Domain II Baculo_PEP_C PF04513.7 AEO63605.1 - 6.1 6.6 7.4 1.4 8.7 0.4 2.8 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4404 PF14357.1 AEO63605.1 - 8.2 6.9 9.1 0.81 10.1 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Ribosomal_60s PF00428.14 AEO63606.1 - 3.6e-26 91.3 15.4 4.5e-26 91.0 10.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Jun PF03957.8 AEO63606.1 - 0.046 13.4 0.7 0.056 13.1 0.5 1.1 1 0 0 1 1 1 0 Jun-like transcription factor KfrA_N PF11740.3 AEO63606.1 - 0.2 12.0 8.5 0.3 11.5 5.9 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF4366 PF14283.1 AEO63607.1 - 0.00026 20.4 5.6 3.3 7.0 0.1 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF4366) DUF3824 PF12868.2 AEO63607.1 - 0.0015 19.4 10.8 0.0015 19.4 7.5 12.1 2 2 9 12 12 12 3 Domain of unknwon function (DUF3824) Plasmodium_Vir PF05795.6 AEO63607.1 - 0.082 12.0 2.3 0.17 11.0 1.6 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CopD PF05425.8 AEO63607.1 - 0.26 11.5 1.6 4.9 7.4 0.2 3.0 3 0 0 3 3 3 0 Copper resistance protein D DUF2910 PF11139.3 AEO63607.1 - 4.3 6.4 4.3 8.9 5.3 2.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2910) Ribosomal_60s PF00428.14 AEO63607.1 - 9.1 6.7 21.9 36 4.8 0.1 3.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein DnaJ PF00226.26 AEO63608.1 - 8.1e-28 95.9 2.8 1.3e-27 95.2 1.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 AEO63608.1 - 6.6e-16 58.1 15.3 1.1e-15 57.4 10.6 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 AEO63608.1 - 3.6e-14 52.4 0.0 1.5e-13 50.4 0.0 2.0 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 AEO63608.1 - 0.065 12.9 8.4 0.66 9.6 0.9 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Antiterm PF03589.8 AEO63608.1 - 1.3 9.2 3.5 2.4 8.3 1.2 2.4 1 1 1 2 2 2 0 Antitermination protein DZR PF12773.2 AEO63608.1 - 4.5 7.1 11.3 5.4 6.9 1.6 2.2 1 1 2 3 3 3 0 Double zinc ribbon Methyltransf_23 PF13489.1 AEO63609.1 - 9e-13 48.2 0.0 1.4e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO63609.1 - 9.9e-06 25.9 0.0 1.6e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO63609.1 - 0.00011 22.1 0.0 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO63609.1 - 0.00024 21.5 0.0 0.00037 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO63609.1 - 0.00032 21.2 0.0 0.00057 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Aldo_ket_red PF00248.16 AEO63611.1 - 1.8e-69 233.7 0.0 2e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FA_desaturase PF00487.19 AEO63612.1 - 1.7e-30 106.3 22.2 2.4e-30 105.8 15.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 AEO63612.1 - 2.3e-19 68.3 0.3 5e-19 67.2 0.2 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) HTH_23 PF13384.1 AEO63613.1 - 3.4e-05 23.3 0.1 7.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 AEO63613.1 - 0.0053 16.7 0.1 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.2 AEO63613.1 - 0.0058 16.2 0.1 0.08 12.6 0.1 2.1 2 0 0 2 2 2 1 MarR family HTH_29 PF13551.1 AEO63613.1 - 0.012 15.7 0.3 0.036 14.2 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix HTH_11 PF08279.7 AEO63613.1 - 0.038 13.6 0.1 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 HTH domain HTH_Tnp_Tc3_1 PF11427.3 AEO63613.1 - 0.098 12.3 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Tc3 transposase HTH_Tnp_4 PF13613.1 AEO63613.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Vac7 PF12751.2 AEO63614.1 - 1.4e-107 359.9 19.5 9.9e-95 317.6 2.3 3.2 3 0 0 3 3 3 2 Vacuolar segregation subunit 7 Z1 PF10593.4 AEO63616.1 - 0.079 12.1 4.7 0.18 11.0 3.3 1.6 1 0 0 1 1 1 0 Z1 domain SPX PF03105.14 AEO63616.1 - 0.1 12.3 13.5 0.14 11.8 7.7 2.2 2 0 0 2 2 2 0 SPX domain LMBR1 PF04791.11 AEO63616.1 - 0.38 9.2 9.2 0.63 8.5 6.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1515 PF07439.6 AEO63616.1 - 0.79 9.5 12.5 1.1 9.1 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) PXA PF02194.10 AEO63616.1 - 1.5 8.3 14.0 1 8.9 6.2 2.2 2 0 0 2 2 2 0 PXA domain TTKRSYEDQ PF10212.4 AEO63616.1 - 5 5.9 15.4 0.77 8.6 5.7 2.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Asp-B-Hydro_N PF05279.6 AEO63616.1 - 6.4 6.5 23.1 0.33 10.7 12.4 1.5 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Zn_clus PF00172.13 AEO63617.1 - 4.5e-07 29.6 7.3 8.7e-07 28.7 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO63617.1 - 4.9e-06 25.6 0.0 6.1e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dickkopf_N PF04706.7 AEO63617.1 - 5.9 7.1 11.1 20 5.4 7.7 1.9 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region MFS_1 PF07690.11 AEO63618.1 - 7.2e-27 94.0 35.9 7.2e-27 94.0 24.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L7Ae PF01248.21 AEO63619.1 - 1e-24 85.8 0.0 1.1e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.13 AEO63620.1 - 5.4e-32 110.3 0.1 7.2e-32 109.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e NPV_P10 PF05531.7 AEO63622.1 - 0.025 14.8 0.4 0.55 10.5 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RrnaAD PF00398.15 AEO63623.1 - 2.6e-50 170.8 0.0 3.8e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 AEO63623.1 - 1.8e-10 40.8 0.0 4.4e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO63623.1 - 2.2e-05 25.0 0.0 5.8e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 AEO63623.1 - 0.00028 20.5 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 AEO63623.1 - 0.0007 19.2 0.0 0.0037 16.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 AEO63623.1 - 0.0016 17.6 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 AEO63623.1 - 0.0017 17.7 0.0 0.0037 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 AEO63623.1 - 0.0094 15.5 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.1 AEO63623.1 - 0.013 15.2 0.1 0.044 13.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.14 AEO63623.1 - 0.016 14.7 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cwf_Cwc_15 PF04889.7 AEO63623.1 - 0.026 14.2 8.5 0.037 13.7 5.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.8 AEO63623.1 - 0.073 12.6 7.4 0.11 12.0 5.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 AEO63623.1 - 0.081 10.9 6.1 0.1 10.5 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 AEO63623.1 - 0.35 8.7 14.1 0.46 8.3 9.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 AEO63623.1 - 0.43 9.8 14.0 0.61 9.3 9.7 1.1 1 0 0 1 1 1 0 SDA1 DUF1510 PF07423.6 AEO63623.1 - 0.45 9.8 7.0 0.66 9.3 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) YL1 PF05764.8 AEO63623.1 - 1.2 8.6 11.4 1.8 8.1 7.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein TRAP_alpha PF03896.11 AEO63623.1 - 1.4 7.8 6.2 1.9 7.3 4.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Astro_capsid PF03115.9 AEO63623.1 - 2.1 6.4 4.2 2.9 6.0 2.9 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor BUD22 PF09073.5 AEO63623.1 - 2.2 7.2 14.7 3.2 6.7 10.2 1.1 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 AEO63623.1 - 5 5.4 12.8 6.6 5.0 8.9 1.1 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 AEO63623.1 - 5.4 6.1 10.9 8.9 5.4 7.6 1.3 1 0 0 1 1 1 0 NOA36 protein Arrestin_N PF00339.24 AEO63624.1 - 8.1e-14 51.6 0.2 2.4e-06 27.4 0.0 2.8 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain SRC-1 PF08832.5 AEO63624.1 - 0.071 13.8 0.0 0.15 12.8 0.0 1.4 1 0 0 1 1 1 0 Steroid receptor coactivator zf-MIZ PF02891.15 AEO63625.1 - 3.3e-08 32.9 9.9 6.6e-07 28.7 1.5 2.7 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger UTP15_C PF09384.5 AEO63626.1 - 2.7e-44 150.4 0.0 4.1e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 AEO63626.1 - 1.3e-27 94.6 1.8 1e-08 34.7 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Pkinase PF00069.20 AEO63627.1 - 1.1e-71 241.0 0.0 1.3e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO63627.1 - 3.5e-31 108.2 0.0 4.8e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO63627.1 - 0.016 14.9 0.1 0.065 12.9 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 AEO63627.1 - 0.079 12.0 0.0 0.21 10.6 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LMWPc PF01451.16 AEO63628.1 - 3.5e-36 124.5 0.0 3.9e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SIS PF01380.17 AEO63629.1 - 1.3e-12 47.4 0.0 3.6e-12 46.0 0.0 1.7 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 AEO63629.1 - 0.00069 19.3 0.0 0.002 17.8 0.0 1.7 1 1 0 1 1 1 1 SIS domain DEC-1_N PF04625.8 AEO63629.1 - 6.9 5.2 10.7 15 4.0 7.4 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF2373 PF10180.4 AEO63630.1 - 1.4e-22 79.0 0.2 1.5e-21 75.6 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Death_2 PF14786.1 AEO63630.1 - 0.05 13.3 0.6 0.11 12.2 0.2 1.7 2 0 0 2 2 2 0 Tube Death domain Proteasome PF00227.21 AEO63631.1 - 2.1e-48 164.1 0.0 2.7e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AEO63631.1 - 1.9e-13 49.4 0.1 1.9e-13 49.4 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF3650 PF12368.3 AEO63631.1 - 0.88 9.1 3.6 0.41 10.1 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) UPF0546 PF10639.4 AEO63633.1 - 2.1e-15 56.5 0.0 1.1e-14 54.1 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 Retinal PF15449.1 AEO63633.1 - 0.071 10.7 0.6 0.089 10.4 0.4 1.0 1 0 0 1 1 1 0 Retinal protein DUF4381 PF14316.1 AEO63633.1 - 0.17 12.0 1.9 0.27 11.3 1.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) DUF485 PF04341.7 AEO63633.1 - 0.23 11.1 2.3 1.9 8.2 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF485 Glyco_hydro_47 PF01532.15 AEO63634.1 - 1e-159 532.0 0.0 1.2e-159 531.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SKG6 PF08693.5 AEO63635.1 - 0.0028 16.9 0.2 0.0028 16.9 0.1 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain C2 PF00168.25 AEO63636.1 - 1.6e-11 43.8 0.1 2.6e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 C2 domain DUF3668 PF12416.3 AEO63636.1 - 0.2 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Cep120 protein NT-C2 PF10358.4 AEO63636.1 - 0.25 10.8 0.0 0.41 10.1 0.0 1.2 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins DUF3455 PF11937.3 AEO63637.1 - 5.8e-33 114.3 0.0 8.4e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DNA_pol_A_exo1 PF01612.15 AEO63638.1 - 8.3e-09 35.1 0.0 6e-07 29.1 0.0 2.1 2 0 0 2 2 2 2 3'-5' exonuclease 4HBT_2 PF13279.1 AEO63639.1 - 0.00083 19.7 0.0 0.0018 18.7 0.0 1.6 2 0 0 2 2 2 1 Thioesterase-like superfamily 4HBT PF03061.17 AEO63640.1 - 0.00016 21.6 4.5 0.00021 21.3 0.0 2.8 3 0 0 3 3 3 1 Thioesterase superfamily ATP-grasp_4 PF13535.1 AEO63642.1 - 3.7e-18 65.9 0.1 2.1e-16 60.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AEO63642.1 - 5.5e-05 22.6 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus NAS PF03059.11 AEO63643.1 - 8.2e-63 212.1 0.0 3.8e-37 127.9 0.0 2.1 2 0 0 2 2 2 2 Nicotianamine synthase protein MBOAT_2 PF13813.1 AEO63645.1 - 2.1e-17 62.9 6.5 3.3e-17 62.3 4.5 1.3 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Peptidase_A4 PF01828.12 AEO63648.1 - 1.2e-77 259.7 5.6 1.3e-77 259.5 3.9 1.0 1 0 0 1 1 1 1 Peptidase A4 family 2OG-FeII_Oxy_2 PF13532.1 AEO63649.1 - 2.1e-19 70.1 0.0 7.1e-19 68.3 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 AEO63649.1 - 4e-11 43.0 0.3 2.2e-05 24.6 0.0 2.9 2 1 1 3 3 3 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 AEO63649.1 - 0.082 13.4 1.1 0.2 12.1 0.1 2.4 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily DUF3439 PF11921.3 AEO63649.1 - 0.21 11.3 7.9 0.43 10.3 5.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 AEO63649.1 - 0.72 7.5 8.5 0.96 7.1 5.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RVT_1 PF00078.22 AEO63650.1 - 7.1e-06 25.5 0.8 9e-06 25.1 0.5 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exonuc_V_gamma PF04257.9 AEO63650.1 - 0.17 9.8 1.0 0.23 9.4 0.7 1.2 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit Ribosomal_60s PF00428.14 AEO63652.1 - 0.45 10.9 15.4 0.056 13.8 2.6 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Hexapep PF00132.19 AEO63653.1 - 4.3e-11 41.7 6.0 2.9e-06 26.5 0.7 4.4 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AEO63653.1 - 2.5e-06 26.9 1.4 0.01 15.3 0.0 3.5 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 AEO63653.1 - 0.042 12.4 0.0 0.057 11.9 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase Rhodanese PF00581.15 AEO63654.1 - 2.6e-10 40.6 0.0 3.9e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_23 PF13489.1 AEO63656.1 - 4.4e-14 52.5 0.0 1.3e-13 50.9 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO63656.1 - 0.00042 20.7 0.0 0.0011 19.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO63656.1 - 0.0016 18.0 0.0 0.36 10.4 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 AEO63656.1 - 0.0073 16.7 0.0 0.019 15.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO63656.1 - 0.0076 16.8 0.0 0.081 13.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain APH PF01636.18 AEO63657.1 - 1.6e-05 24.7 1.7 1.9e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 AEO63657.1 - 0.00013 21.1 0.0 0.00022 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 AEO63657.1 - 0.00033 20.3 0.0 0.00049 19.7 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase F-box-like PF12937.2 AEO63658.1 - 5.7e-05 22.7 1.0 0.00015 21.4 0.7 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO63658.1 - 0.0021 17.6 0.3 0.0021 17.6 0.2 2.2 2 0 0 2 2 2 1 F-box domain FAD_binding_3 PF01494.14 AEO63659.1 - 1.6e-12 47.1 0.0 2.9e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO63659.1 - 3e-06 26.3 0.0 0.029 13.2 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO63659.1 - 0.024 14.6 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 AEO63659.1 - 0.11 12.9 0.0 0.9 9.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3129 PF11327.3 AEO63660.1 - 7e-51 172.6 8.4 7e-51 172.6 5.9 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3129) ASFV_J13L PF05568.6 AEO63660.1 - 2 7.9 7.0 3.5 7.1 4.9 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Dioxygenase_C PF00775.16 AEO63661.1 - 1.8e-08 33.8 0.1 4.1e-08 32.6 0.1 1.6 1 1 0 1 1 1 1 Dioxygenase Sugar_tr PF00083.19 AEO63663.1 - 1.6e-96 323.6 19.1 2.8e-66 223.9 6.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 AEO63663.1 - 2.2e-17 62.8 31.1 4.7e-10 38.7 2.7 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily polyprenyl_synt PF00348.12 AEO63664.1 - 2.2e-21 75.9 0.0 4.3e-19 68.3 0.0 2.3 1 1 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 AEO63664.1 - 2.1e-05 23.8 0.1 0.00013 21.3 0.1 2.0 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Sugar_tr PF00083.19 AEO63665.1 - 3.7e-76 256.5 20.8 4.3e-76 256.3 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO63665.1 - 3.1e-23 82.0 27.0 2.2e-19 69.3 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO63665.1 - 0.00011 20.7 1.1 0.00011 20.7 0.8 3.4 2 1 0 3 3 3 1 MFS/sugar transport protein RSS_P20 PF11757.3 AEO63665.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like F-box-like PF12937.2 AEO63666.1 - 2.8e-09 36.5 0.5 6.8e-09 35.3 0.4 1.7 1 0 0 1 1 1 1 F-box-like Dispanin PF04505.7 AEO63666.1 - 0.083 12.4 0.0 0.3 10.6 0.0 1.9 1 0 0 1 1 1 0 Interferon-induced transmembrane protein EamA PF00892.15 AEO63667.1 - 4.4e-12 46.1 26.2 2.8e-06 27.4 1.2 2.5 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 AEO63667.1 - 3e-05 24.1 2.3 3e-05 24.1 1.6 3.1 3 0 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 AEO63667.1 - 0.0065 16.1 11.5 0.0065 16.1 7.9 3.1 2 1 0 2 2 2 1 Triose-phosphate Transporter family Ank PF00023.25 AEO63669.1 - 2e-16 58.8 1.7 5.6e-07 29.0 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 AEO63669.1 - 9.4e-13 48.3 0.0 0.00014 22.1 0.0 3.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AEO63669.1 - 3.8e-12 46.3 1.0 0.00027 21.3 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO63669.1 - 1.8e-11 43.9 0.3 4e-05 23.7 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO63669.1 - 5.5e-08 32.3 0.4 0.37 11.1 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat KilA-N PF04383.8 AEO63669.1 - 4.1e-06 26.3 0.0 1.3e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 KilA-N domain RVT_1 PF00078.22 AEO63670.1 - 0.0035 16.7 0.3 0.0043 16.4 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 4HBT_3 PF13622.1 AEO63671.1 - 6.8 6.3 11.0 7.6 6.1 2.1 2.0 2 0 0 2 2 2 0 Thioesterase-like superfamily Aldo_ket_red PF00248.16 AEO63674.1 - 1.4e-45 155.3 0.0 1.6e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peroxidase_2 PF01328.12 AEO63675.1 - 5.9e-34 117.1 0.0 8e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 SSP160 PF06933.6 AEO63677.1 - 3.1 5.6 5.7 3.9 5.3 3.9 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NDUF_B7 PF05676.8 AEO63678.1 - 1.8e-31 107.3 3.8 2.1e-31 107.1 2.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Bcr-Abl_Oligo PF09036.5 AEO63678.1 - 0.041 13.8 0.2 0.052 13.5 0.1 1.2 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain Cmc1 PF08583.5 AEO63678.1 - 0.072 12.8 2.7 0.087 12.6 1.6 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Glyco_hydro_11 PF00457.12 AEO63680.1 - 2.5e-64 216.0 10.6 2.9e-64 215.8 7.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Pkinase PF00069.20 AEO63681.1 - 0.034 13.3 0.0 0.074 12.1 0.0 1.4 1 1 0 1 1 1 0 Protein kinase domain HSP20 PF00011.16 AEO63685.1 - 1e-20 73.5 0.1 1.6e-19 69.6 0.0 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family HATPase_c PF02518.21 AEO63686.1 - 3.8e-26 90.9 0.0 7.8e-26 89.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 AEO63686.1 - 8.4e-24 83.7 0.2 1.6e-23 82.8 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 AEO63686.1 - 1.1e-18 66.9 0.1 4.3e-18 65.0 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 AEO63686.1 - 2.2e-17 63.3 0.0 4.2e-16 59.2 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 AEO63686.1 - 3e-09 36.6 0.0 1.2e-08 34.7 0.0 2.1 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 AEO63686.1 - 3.3e-07 30.2 0.2 9.3e-05 22.4 0.0 2.8 2 0 0 2 2 2 2 PAS fold FAD_binding_3 PF01494.14 AEO63687.1 - 5.5e-15 55.2 0.2 3.9e-13 49.1 0.1 2.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO63687.1 - 1.5e-10 40.5 1.6 5.2e-06 25.5 0.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO63687.1 - 8.1e-08 31.5 1.3 1.1e-07 31.0 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 AEO63687.1 - 1.5e-07 31.2 0.2 3.8e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AEO63687.1 - 1.6e-06 28.1 0.2 8.2e-06 25.8 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO63687.1 - 2.2e-06 26.4 0.1 1.3e-05 23.8 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 AEO63687.1 - 8.1e-06 25.1 0.6 2.9e-05 23.3 0.4 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 AEO63687.1 - 1.6e-05 23.9 0.0 2.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 AEO63687.1 - 5.5e-05 23.4 0.0 0.0024 18.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 AEO63687.1 - 0.00041 19.0 0.1 0.39 9.2 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 AEO63687.1 - 0.0018 18.3 0.2 0.0034 17.4 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 AEO63687.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 AEO63687.1 - 0.011 14.6 0.2 0.048 12.5 0.1 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein FMO-like PF00743.14 AEO63687.1 - 0.033 12.3 0.1 0.045 11.9 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Amino_oxidase PF01593.19 AEO63687.1 - 0.058 12.4 0.3 1.4 7.8 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.9 AEO63687.1 - 0.069 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 AEO63687.1 - 0.083 12.5 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 AEO63687.1 - 0.096 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 AEO63687.1 - 0.12 11.5 0.4 0.23 10.4 0.1 1.6 2 0 0 2 2 2 0 Thi4 family DUF946 PF06101.6 AEO63688.1 - 3.5e-10 38.5 0.1 6.8e-10 37.5 0.1 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) DUF1302 PF06980.6 AEO63688.1 - 0.0018 16.9 0.2 0.014 14.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1302) TFIIIC_sub6 PF10419.4 AEO63689.1 - 1.5e-14 53.1 0.0 2.6e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit His_biosynth PF00977.16 AEO63690.1 - 6.8e-49 166.2 0.2 3e-48 164.0 0.2 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 AEO63690.1 - 3.9e-27 94.9 0.0 6.5e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 AEO63690.1 - 1.7e-07 31.0 0.0 2.6e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 AEO63690.1 - 8.5e-07 28.6 0.0 3.6e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.12 AEO63690.1 - 0.0076 15.1 0.0 0.017 13.9 0.0 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.8 AEO63690.1 - 0.029 13.8 0.1 0.62 9.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 ODC_AZ PF02100.12 AEO63691.1 - 1e-25 89.3 0.0 1.6e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme MAGE_N PF12440.3 AEO63691.1 - 0.13 12.5 6.7 0.43 10.8 3.5 2.5 2 1 1 3 3 3 0 Melanoma associated antigen family N terminal Yippee-Mis18 PF03226.9 AEO63692.1 - 4.1e-17 62.0 0.0 6.6e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 AEO63692.1 - 0.0042 16.9 0.0 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 C-terminal domain of RIG-I Peptidase_M20 PF01546.23 AEO63693.1 - 6.8e-31 107.2 0.0 1.5e-30 106.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AEO63693.1 - 5.2e-14 51.9 0.0 8.9e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Leu_zip PF15294.1 AEO63694.1 - 0.015 14.3 8.1 0.021 13.9 5.6 1.1 1 0 0 1 1 1 0 Leucine zipper DivIVA PF05103.8 AEO63694.1 - 0.022 14.7 7.4 0.062 13.3 5.1 1.7 1 1 0 1 1 1 0 DivIVA protein Exonuc_VII_L PF02601.10 AEO63694.1 - 0.4 9.8 4.5 0.58 9.2 3.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Seryl_tRNA_N PF02403.17 AEO63694.1 - 0.53 10.3 7.7 0.79 9.7 0.5 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 AEO63694.1 - 3.5 7.1 14.5 5.3 6.6 10.1 1.2 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 AEO63694.1 - 4 7.8 8.2 0.7 10.3 0.2 2.6 2 1 0 2 2 2 0 SlyX Peptidase_S8 PF00082.17 AEO63696.1 - 1.3e-49 168.9 15.0 1.6e-49 168.5 10.4 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 AEO63696.1 - 1.1e-08 35.4 0.0 2.9e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF2681 PF10883.3 AEO63697.1 - 0.051 13.7 0.1 0.091 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF515 PF04415.7 AEO63697.1 - 5.2 5.1 5.9 6.5 4.8 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) FliP PF00813.15 AEO63698.1 - 0.004 16.8 2.3 0.0052 16.5 1.6 1.3 1 0 0 1 1 1 1 FliP family FA_synthesis PF02504.10 AEO63698.1 - 0.56 9.0 5.8 0.69 8.7 4.0 1.1 1 0 0 1 1 1 0 Fatty acid synthesis protein AMP-binding PF00501.23 AEO63699.1 - 1.2e-70 237.9 0.0 1.8e-70 237.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO63699.1 - 5.9e-11 43.1 0.1 1.6e-10 41.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PMI_typeI PF01238.16 AEO63700.1 - 5.3e-138 460.0 0.0 6.2e-138 459.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 AEO63700.1 - 0.0028 17.3 0.0 2.2 7.9 0.0 2.7 3 0 0 3 3 3 2 AraC-like ligand binding domain Focal_AT PF03623.8 AEO63700.1 - 0.045 13.2 0.2 0.086 12.3 0.2 1.3 1 0 0 1 1 1 0 Focal adhesion targeting region DUF1325 PF07039.6 AEO63701.1 - 1.3e-25 89.4 0.1 2.5e-25 88.5 0.0 1.5 2 0 0 2 2 2 1 SGF29 tudor-like domain Arf PF00025.16 AEO63702.1 - 3.8e-72 241.1 0.0 4.3e-72 240.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AEO63702.1 - 2.3e-14 53.0 0.0 2.7e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AEO63702.1 - 2.3e-12 46.5 0.0 2.7e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 AEO63702.1 - 6.1e-12 44.9 0.9 6.1e-08 31.7 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 AEO63702.1 - 6.7e-10 38.4 0.0 8.2e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AEO63702.1 - 3.2e-06 27.6 0.0 4.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AEO63702.1 - 0.00021 21.2 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 AEO63702.1 - 0.0059 15.6 0.0 0.0084 15.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Pkinase PF00069.20 AEO63703.1 - 1.6e-62 211.0 0.0 3.3e-62 210.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO63703.1 - 1.6e-30 106.0 0.0 3e-30 105.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO63703.1 - 0.0094 14.9 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO63703.1 - 0.011 15.5 0.0 0.23 11.1 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Actin PF00022.14 AEO63704.1 - 1.6e-117 392.2 0.0 2e-117 391.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AEO63704.1 - 0.028 13.0 0.0 0.15 10.6 0.0 2.0 1 1 0 1 1 1 0 MreB/Mbl protein Asp_Glu_race PF01177.17 AEO63705.1 - 7e-22 78.4 0.0 8.3e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Sugar_tr PF00083.19 AEO63706.1 - 2.8e-85 286.5 22.3 1.2e-83 281.1 15.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO63706.1 - 3.8e-37 127.8 55.4 3.3e-31 108.3 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 AEO63706.1 - 6.3e-10 37.8 3.7 6.3e-10 37.8 2.6 2.2 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NmrA PF05368.8 AEO63707.1 - 1.3e-32 112.9 0.0 1.5e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO63707.1 - 2.5e-12 47.1 0.0 3.8e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 AEO63707.1 - 4.2e-07 28.9 0.0 6.4e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AEO63707.1 - 2.3e-06 27.2 0.0 7.1e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 AEO63707.1 - 8.1e-06 25.6 0.2 3.8e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 AEO63707.1 - 6e-05 23.0 0.1 0.00012 22.0 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 AEO63707.1 - 0.00017 21.8 0.0 0.0004 20.6 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 AEO63707.1 - 0.0016 18.3 0.0 0.0048 16.8 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain Polysacc_synt_2 PF02719.10 AEO63707.1 - 0.0017 17.3 0.0 0.003 16.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 AEO63707.1 - 0.011 14.7 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 AEO63707.1 - 0.051 12.4 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein F420_oxidored PF03807.12 AEO63707.1 - 0.13 12.7 0.1 0.28 11.6 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SHS2_Rpb7-N PF03876.12 AEO63709.1 - 5.5e-08 32.8 0.0 1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pro_isomerase PF00160.16 AEO63712.1 - 3.6e-31 108.4 0.0 5.4e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 AEO63712.1 - 2.4e-16 59.1 0.0 4.3e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO63712.1 - 6.7e-11 42.0 0.0 1.4e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO63712.1 - 7e-10 38.6 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 AEO63713.1 - 3.5e-09 36.4 8.1 5e-09 35.9 5.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_16 PF10294.4 AEO63714.1 - 3.5e-18 65.6 0.0 5.4e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 AEO63714.1 - 1.2e-06 29.0 0.0 3.5e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO63714.1 - 3.8e-05 23.4 0.0 0.0001 22.0 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain PCMT PF01135.14 AEO63714.1 - 0.00046 19.7 0.0 0.00098 18.7 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 AEO63714.1 - 0.005 16.0 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.12 AEO63714.1 - 0.01 14.9 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 AEO63714.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 AEO63714.1 - 0.03 14.3 0.1 0.073 13.1 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 AEO63714.1 - 0.038 13.5 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 AEO63714.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) AA_kinase PF00696.23 AEO63714.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Amino acid kinase family Ribosomal_S24e PF01282.14 AEO63715.1 - 3e-37 126.2 0.0 4.7e-37 125.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e GTP_cyclohydro2 PF00925.15 AEO63717.1 - 5.4e-57 191.7 0.0 1.3e-51 174.2 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II DUF2458 PF10454.4 AEO63718.1 - 0.13 12.1 4.9 0.1 12.4 2.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2458) Abhydrolase_6 PF12697.2 AEO63719.1 - 1.7e-35 122.9 2.9 2.3e-35 122.5 2.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO63719.1 - 2.6e-16 59.8 0.0 3.7e-08 33.2 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO63719.1 - 1.3e-15 57.3 0.2 3.5e-15 56.0 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 AEO63719.1 - 0.0058 16.2 0.7 0.009 15.6 0.5 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 AEO63719.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Lipase_3 PF01764.20 AEO63719.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 AEO63719.1 - 0.032 14.4 0.0 0.035 14.3 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Ndr PF03096.9 AEO63719.1 - 0.042 12.3 0.0 0.064 11.7 0.0 1.3 1 0 0 1 1 1 0 Ndr family Hydrolase_4 PF12146.3 AEO63719.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Ser_hydrolase PF06821.8 AEO63719.1 - 0.14 11.7 0.7 0.44 10.1 0.2 1.8 2 0 0 2 2 2 0 Serine hydrolase PGAP1 PF07819.8 AEO63719.1 - 0.14 11.6 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Aa_trans PF01490.13 AEO63720.1 - 1.1e-16 60.3 23.9 2.3e-16 59.3 16.5 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 AEO63720.1 - 0.00059 18.5 2.9 0.00059 18.5 2.0 2.7 2 1 1 3 3 3 1 Spore germination protein DUF1399 PF07173.7 AEO63721.1 - 2.9e-21 76.1 0.3 3.9e-18 66.0 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1399) Fer4_7 PF12838.2 AEO63722.1 - 0.0014 18.9 5.1 0.0014 18.9 3.6 2.9 2 2 0 2 2 2 1 4Fe-4S dicluster domain F-box-like PF12937.2 AEO63722.1 - 0.019 14.7 0.2 0.098 12.4 0.0 2.3 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 AEO63722.1 - 0.086 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 F-box domain Phage_CRI PF05144.9 AEO63723.1 - 0.1 11.6 0.3 0.18 10.8 0.2 1.3 1 0 0 1 1 1 0 Phage replication protein CRI Lipase_3 PF01764.20 AEO63724.1 - 2.6e-10 40.0 0.0 5.6e-10 38.9 0.0 1.5 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 AEO63724.1 - 0.015 15.0 0.0 0.053 13.2 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 AEO63724.1 - 0.022 14.0 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 AEO63724.1 - 0.025 14.4 0.1 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 AEO63724.1 - 0.099 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DDE_1 PF03184.14 AEO63725.1 - 0.02 14.0 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF2258 PF10015.4 AEO63725.1 - 0.082 12.7 0.7 0.096 12.5 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) adh_short PF00106.20 AEO63726.1 - 3.4e-07 30.3 2.4 5.2e-06 26.4 0.3 2.7 2 1 1 3 3 3 2 short chain dehydrogenase KR PF08659.5 AEO63726.1 - 0.0016 18.1 0.1 0.0059 16.2 0.0 1.8 2 0 0 2 2 2 1 KR domain RGS PF00615.14 AEO63727.1 - 1.1e-09 38.3 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_C48 PF02902.14 AEO63728.1 - 2.7e-17 63.1 0.0 4.7e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FKBP_N PF01346.13 AEO63728.1 - 8.3 6.4 5.6 16 5.5 3.9 1.4 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase MFS_1 PF07690.11 AEO63729.1 - 6.5e-25 87.5 59.5 6.4e-15 54.7 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Kelch_4 PF13418.1 AEO63730.1 - 3.4e-09 36.3 8.5 1e-07 31.6 0.1 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain LCM PF04072.9 AEO63730.1 - 1.7e-08 34.2 0.0 2.6e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_3 PF13415.1 AEO63730.1 - 0.00072 19.6 1.4 2.2 8.5 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 AEO63730.1 - 0.0011 19.0 1.3 0.12 12.5 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Cupin_8 PF13621.1 AEO63731.1 - 9.1e-22 77.7 0.0 1.1e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 AEO63731.1 - 1.1e-05 24.8 0.0 1.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Mito_carr PF00153.22 AEO63732.1 - 1.1e-45 153.2 10.7 1.3e-17 63.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 AEO63733.1 - 2.8e-10 39.4 51.7 5.5e-07 28.6 19.7 3.4 3 1 1 4 4 4 2 Major Facilitator Superfamily Nodulin-like PF06813.8 AEO63733.1 - 0.0001 21.6 9.0 0.0047 16.2 0.4 3.3 3 0 0 3 3 3 2 Nodulin-like Pkinase PF00069.20 AEO63734.1 - 1.4e-23 83.3 0.0 1.8e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO63734.1 - 1.2e-11 44.1 0.0 1.3e-10 40.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO63735.1 - 1.3e-08 34.8 0.0 2.5e-08 33.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Dynactin PF12455.3 AEO63736.1 - 1.4e-91 306.2 8.3 1.4e-91 306.2 5.8 3.6 3 0 0 3 3 3 2 Dynein associated protein CAP_GLY PF01302.20 AEO63736.1 - 5.5e-23 80.4 0.4 9.1e-23 79.7 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain SRP19 PF01922.12 AEO63737.1 - 5.7e-27 94.1 0.0 1e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Myosin_tail_1 PF01576.14 AEO63738.1 - 0.0038 15.0 1.0 0.0046 14.7 0.7 1.0 1 0 0 1 1 1 1 Myosin tail Tropomyosin PF00261.15 AEO63738.1 - 0.0053 15.8 0.8 0.0072 15.4 0.5 1.1 1 0 0 1 1 1 1 Tropomyosin Striatin PF08232.7 AEO63738.1 - 0.0058 16.9 0.0 0.0072 16.6 0.0 1.2 1 0 0 1 1 1 1 Striatin family DUF1192 PF06698.6 AEO63738.1 - 0.019 14.7 1.1 0.05 13.4 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Cep57_CLD_2 PF14197.1 AEO63738.1 - 0.02 14.8 1.5 0.031 14.2 1.1 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Reo_sigmaC PF04582.7 AEO63738.1 - 0.12 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF2360 PF10152.4 AEO63738.1 - 1.1 9.5 4.4 2.3 8.4 3.0 1.6 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Methyltransf_31 PF13847.1 AEO63739.1 - 3.8e-28 97.9 0.0 5.2e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO63739.1 - 2.3e-17 63.2 0.0 4.5e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO63739.1 - 2.2e-14 53.5 0.0 3.2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO63739.1 - 9.9e-14 51.5 0.0 1.6e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO63739.1 - 5.5e-13 48.5 0.0 8.7e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 AEO63739.1 - 1.8e-11 44.3 0.0 2.7e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO63739.1 - 4.6e-11 43.3 0.0 8.1e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO63739.1 - 7.1e-10 38.9 0.1 1.3e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AEO63739.1 - 3.6e-06 26.6 0.0 6.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 AEO63739.1 - 4.5e-05 22.7 0.0 7.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 AEO63739.1 - 0.0036 16.7 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 AEO63739.1 - 0.0039 16.3 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase CheR PF01739.13 AEO63739.1 - 0.04 13.1 0.0 0.094 11.9 0.0 1.5 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain UPF0020 PF01170.13 AEO63739.1 - 0.057 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 AEO63739.1 - 0.072 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PemK PF02452.12 AEO63740.1 - 0.026 14.7 0.0 0.054 13.7 0.0 1.4 1 1 0 1 1 1 0 PemK-like protein Fungal_trans_2 PF11951.3 AEO63741.1 - 0.11 11.0 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain adh_short PF00106.20 AEO63742.1 - 2.5e-13 50.2 0.2 3.7e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO63742.1 - 4e-07 29.8 0.1 6.8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NTP_transf_2 PF01909.18 AEO63743.1 - 8.3e-08 32.4 0.0 8.9e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 Nucleotidyltransferase domain Nuc-transf PF10127.4 AEO63743.1 - 0.0024 17.2 0.1 0.01 15.1 0.0 2.0 2 1 0 2 2 2 1 Predicted nucleotidyltransferase RTA1 PF04479.8 AEO63744.1 - 6.4e-25 87.9 4.2 9.1e-25 87.4 2.9 1.2 1 0 0 1 1 1 1 RTA1 like protein Lactonase PF10282.4 AEO63745.1 - 1.2e-90 304.0 0.1 1.7e-90 303.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller MARVEL PF01284.18 AEO63746.1 - 0.00038 20.2 5.5 0.00051 19.8 3.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain SdpI PF13630.1 AEO63746.1 - 0.43 10.3 4.7 2 8.2 2.0 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF3687 PF12459.3 AEO63746.1 - 9.2 5.5 8.1 28 4.0 0.4 3.0 2 1 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein DUF4188 PF13826.1 AEO63747.1 - 1.7e-32 111.9 0.0 2.4e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 AEO63747.1 - 0.0029 16.7 0.0 0.0039 16.2 0.0 1.2 1 0 0 1 1 1 1 Haem-containing dehydratase Dabb PF07876.7 AEO63747.1 - 0.016 15.6 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain Neurensin PF14927.1 AEO63747.1 - 0.059 12.7 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Neurensin Sugar_tr PF00083.19 AEO63748.1 - 1.3e-81 274.5 16.9 1.4e-81 274.3 11.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO63748.1 - 5.1e-28 97.7 17.0 7.3e-28 97.2 11.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO63748.1 - 2.7e-05 22.5 7.3 6.7e-05 21.2 0.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 AEO63748.1 - 4.1e-05 22.1 11.1 4.2e-05 22.1 0.6 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein Tmemb_170 PF10190.4 AEO63748.1 - 0.14 12.1 0.3 0.14 12.1 0.2 2.5 2 1 1 3 3 3 0 Putative transmembrane protein 170 PepSY_TM_2 PF13703.1 AEO63749.1 - 0.029 14.5 0.9 0.037 14.2 0.7 1.1 1 0 0 1 1 1 0 PepSY-associated TM helix DUF4342 PF14242.1 AEO63749.1 - 0.05 13.3 0.5 0.062 13.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) HemY_N PF07219.8 AEO63749.1 - 0.12 11.9 0.6 0.15 11.6 0.4 1.1 1 0 0 1 1 1 0 HemY protein N-terminus DUF4400 PF14348.1 AEO63749.1 - 0.2 10.9 0.8 0.25 10.6 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) F-box PF00646.28 AEO63750.1 - 2.2e-05 23.9 0.4 2.2e-05 23.9 0.3 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 AEO63750.1 - 0.022 14.4 0.4 0.022 14.4 0.3 2.2 2 0 0 2 2 2 0 F-box-like Lactamase_B PF00753.22 AEO63751.1 - 8.4e-08 32.0 6.4 4.4e-06 26.4 0.2 2.6 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AEO63751.1 - 0.00069 19.2 0.1 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Nucleotid_trans PF03407.11 AEO63752.1 - 1.6e-05 24.7 0.0 2.9e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Fungal_trans PF04082.13 AEO63753.1 - 1.7e-09 36.9 0.0 2.9e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO63753.1 - 2.1e-06 27.5 9.9 4.1e-06 26.6 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ICA69 PF04629.9 AEO63753.1 - 0.21 11.5 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain IF-2B PF01008.12 AEO63754.1 - 3.4e-23 82.0 0.0 8.7e-23 80.7 0.0 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.23 AEO63754.1 - 2.3e-11 43.4 0.0 3.9e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain APH PF01636.18 AEO63755.1 - 5.8e-06 26.2 1.1 2.9e-05 23.9 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 AEO63755.1 - 0.0014 17.7 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO63755.1 - 0.0074 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 AEO63755.1 - 0.0095 15.5 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 AEO63755.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family zf-LITAF-like PF10601.4 AEO63758.1 - 8.1e-12 44.8 11.2 1.2e-11 44.3 7.7 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.5 AEO63758.1 - 0.0078 16.1 0.2 1.5 8.8 0.0 2.6 2 0 0 2 2 2 2 Zinc ribbon domain Cys_rich_KTR PF14205.1 AEO63758.1 - 0.053 12.9 0.8 0.053 12.9 0.5 2.0 2 0 0 2 2 2 0 Cysteine-rich KTR zf-H2C2_2 PF13465.1 AEO63758.1 - 5.9 7.3 9.8 4.4 7.7 0.2 2.7 3 0 0 3 3 3 0 Zinc-finger double domain Glyco_hydro_16 PF00722.16 AEO63760.1 - 4e-13 49.0 1.5 5.9e-13 48.5 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CBM_1 PF00734.13 AEO63760.1 - 3.4e-10 39.3 12.5 3.4e-10 39.3 8.7 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain HpcH_HpaI PF03328.9 AEO63762.1 - 2e-20 72.6 0.0 3.9e-20 71.6 0.0 1.5 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 AEO63762.1 - 0.03 12.9 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain DUF1264 PF06884.6 AEO63765.1 - 7.7e-72 240.2 0.0 9e-72 240.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) BRE PF06113.7 AEO63765.1 - 0.031 13.3 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) EBP50_C-term PF09007.6 AEO63765.1 - 0.15 11.9 0.2 0.37 10.6 0.2 1.7 1 1 0 1 1 1 0 EBP50, C-terminal AMP-binding PF00501.23 AEO63766.1 - 7.2e-263 871.2 0.0 3.4e-91 305.7 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 AEO63766.1 - 4.3e-183 606.9 0.0 2.7e-33 115.1 0.0 7.5 7 1 0 7 7 7 6 Condensation domain PP-binding PF00550.20 AEO63766.1 - 9.1e-65 214.8 5.9 3.7e-13 49.5 0.0 7.5 8 0 0 8 8 8 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 AEO63766.1 - 4.5e-17 62.7 0.1 2.8e-05 24.9 0.0 4.5 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Transferase PF02458.10 AEO63766.1 - 0.043 12.2 1.6 11 4.3 0.1 3.0 3 0 0 3 3 3 0 Transferase family K_oxygenase PF13434.1 AEO63767.1 - 6.5e-107 357.3 0.0 8.1e-107 357.0 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 AEO63767.1 - 5.2e-12 46.2 0.0 9.6e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO63767.1 - 3.4e-10 39.9 0.1 8.1e-09 35.4 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 AEO63767.1 - 3.4e-05 23.8 0.0 5.6e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.1 AEO63767.1 - 0.13 11.3 0.0 12 4.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) SSP160 PF06933.6 AEO63768.1 - 0.041 11.8 13.2 0.055 11.4 9.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pol_alpha_B_N PF08418.5 AEO63768.1 - 0.12 11.9 7.4 0.18 11.3 5.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Shisa PF13908.1 AEO63768.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.4 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Sporozoite_P67 PF05642.6 AEO63768.1 - 1 7.1 12.2 1.2 6.9 8.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1183 PF06682.7 AEO63768.1 - 5.4 6.5 10.4 9 5.7 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) FF PF01846.14 AEO63769.1 - 9.1e-10 38.3 6.4 7.5e-09 35.4 0.4 3.1 3 0 0 3 3 3 2 FF domain WW PF00397.21 AEO63769.1 - 2.3e-09 36.9 4.8 2.3e-09 36.9 3.4 2.8 3 0 0 3 3 3 1 WW domain DUF747 PF05346.6 AEO63770.1 - 2.8e-134 447.3 1.7 3.9e-134 446.9 1.2 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family HemY_N PF07219.8 AEO63770.1 - 0.54 9.8 6.2 0.46 10.0 0.6 2.8 2 0 0 2 2 2 0 HemY protein N-terminus DUF3886 PF13025.1 AEO63770.1 - 5.3 7.0 10.0 0.058 13.3 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) Dimer_Tnp_hAT PF05699.9 AEO63771.1 - 0.0085 15.6 0.2 0.009 15.6 0.2 1.2 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region ADH_zinc_N PF00107.21 AEO63773.1 - 6.9e-13 48.2 0.0 1.4e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO63773.1 - 2.1e-09 37.1 0.1 4.3e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AEO63773.1 - 1.4e-05 25.9 0.2 2.7e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Aldo_ket_red PF00248.16 AEO63774.1 - 5.3e-63 212.4 0.0 6.6e-63 212.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DLH PF01738.13 AEO63775.1 - 2.3e-28 99.0 0.0 2.8e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AEO63775.1 - 7.6e-08 32.2 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 AEO63775.1 - 0.11 11.5 0.0 0.5 9.4 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Fructosamin_kin PF03881.9 AEO63776.1 - 1.5e-36 125.8 0.0 2e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 AEO63776.1 - 3e-08 33.6 0.1 5.7e-08 32.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_2_N PF02837.13 AEO63777.1 - 1.5e-34 118.9 0.2 7.4e-33 113.4 0.0 3.3 3 1 0 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 AEO63777.1 - 4.6e-31 107.8 0.0 9e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 AEO63777.1 - 9.7e-13 48.5 0.2 2e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 AEO63777.1 - 0.00021 21.4 2.3 0.0025 18.0 0.0 3.1 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Big_1 PF02369.11 AEO63777.1 - 0.013 15.3 1.9 0.013 15.3 1.3 2.8 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 1) Amidohydro_2 PF04909.9 AEO63780.1 - 2.7e-40 138.6 0.6 3.8e-40 138.1 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase Aldedh PF00171.17 AEO63781.1 - 6.7e-143 476.3 0.6 7.5e-143 476.2 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 AEO63781.1 - 2.8e-05 23.4 0.0 0.14 11.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) FAD_binding_3 PF01494.14 AEO63782.1 - 1.6e-12 47.1 0.1 0.00085 18.4 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 AEO63782.1 - 5.8e-07 29.4 0.0 2.2e-06 27.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 AEO63782.1 - 2e-06 26.9 0.0 3.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 AEO63782.1 - 1.3e-05 25.4 0.1 0.0025 18.1 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AEO63782.1 - 3.5e-05 22.8 0.8 0.00065 18.7 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AEO63782.1 - 6.4e-05 22.9 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO63782.1 - 0.00011 20.7 0.0 0.0013 17.2 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 AEO63782.1 - 0.00013 22.0 0.0 0.0026 17.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AEO63782.1 - 0.00025 20.0 0.0 0.00054 18.9 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 AEO63782.1 - 0.00057 19.0 0.1 0.0014 17.8 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 AEO63782.1 - 0.0015 17.2 0.1 1 7.9 0.0 2.4 3 0 0 3 3 3 2 Tryptophan halogenase AlaDh_PNT_C PF01262.16 AEO63782.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.19 AEO63782.1 - 0.086 11.8 0.0 9 5.2 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.12 AEO63782.1 - 0.086 11.9 0.1 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family p450 PF00067.17 AEO63783.1 - 1.2e-67 228.4 0.0 1.7e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tad PF13400.1 AEO63783.1 - 0.088 12.8 3.6 0.22 11.5 2.5 1.7 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Sugar_tr PF00083.19 AEO63784.1 - 1.1e-80 271.4 23.6 1.2e-80 271.2 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO63784.1 - 1.5e-19 69.9 35.3 1.5e-17 63.3 10.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 AEO63785.1 - 1.7e-64 218.0 0.0 2.7e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Asp PF00026.18 AEO63786.1 - 1.6e-25 90.0 0.0 1e-24 87.3 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 AEO63786.1 - 6.5e-07 29.7 0.1 0.5 10.8 0.0 3.4 3 0 0 3 3 3 3 Aspartyl protease gag-asp_proteas PF13975.1 AEO63786.1 - 0.01 15.6 0.1 6.5 6.6 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_N PF14543.1 AEO63786.1 - 0.087 12.7 0.0 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal FAD_binding_4 PF01565.18 AEO63787.1 - 2.7e-17 62.5 0.1 6.9e-17 61.2 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain GFO_IDH_MocA PF01408.17 AEO63788.1 - 1.6e-15 57.6 0.1 3.1e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold SH3_9 PF14604.1 AEO63789.1 - 1.7e-13 49.8 0.1 3.9e-09 35.9 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 AEO63789.1 - 0.0011 18.4 0.1 0.024 14.0 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 AEO63789.1 - 0.0072 15.6 0.1 0.037 13.4 0.0 2.1 2 0 0 2 2 2 1 SH3 domain Nudix_N PF12535.3 AEO63789.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal U5_2-snRNA_bdg PF10597.4 AEO63789.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 Cerato-platanin PF07249.7 AEO63790.1 - 0.00033 20.6 0.5 0.0009 19.2 0.1 1.8 2 0 0 2 2 2 1 Cerato-platanin NUDIX PF00293.23 AEO63791.1 - 2.8e-16 59.3 0.1 3.4e-16 59.1 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain FAD_binding_4 PF01565.18 AEO63793.1 - 3.1e-26 91.4 3.0 3.1e-26 91.4 2.1 1.7 2 0 0 2 2 2 1 FAD binding domain adh_short PF00106.20 AEO63794.1 - 2.3e-29 102.4 3.8 3.1e-29 102.0 2.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO63794.1 - 2.7e-20 73.1 0.1 3.7e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO63794.1 - 1.2e-11 44.6 2.5 1.6e-11 44.1 1.8 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO63794.1 - 5.8e-11 42.7 0.6 1e-10 41.9 0.4 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO63794.1 - 2.3e-06 27.2 0.2 6.8e-06 25.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 AEO63794.1 - 7.2e-06 25.2 0.2 7.5e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF1776 PF08643.5 AEO63794.1 - 3.4e-05 23.1 0.0 0.00035 19.8 0.0 2.3 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 AEO63794.1 - 3.7e-05 23.0 0.5 5.6e-05 22.5 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family TGS PF02824.16 AEO63794.1 - 0.0017 18.1 0.0 0.01 15.6 0.0 2.2 2 0 0 2 2 2 1 TGS domain PAE PF03283.8 AEO63794.1 - 0.04 12.5 0.6 0.058 12.0 0.4 1.2 1 0 0 1 1 1 0 Pectinacetylesterase 2-Hacid_dh_C PF02826.14 AEO63794.1 - 0.082 12.0 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PhnA_Zn_Ribbon PF08274.7 AEO63795.1 - 0.21 11.3 2.1 8.2 6.3 0.1 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-TFIIB PF13453.1 AEO63795.1 - 0.22 10.7 2.6 3.2 7.0 0.2 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF329 PF03884.9 AEO63795.1 - 0.27 10.8 2.0 10 5.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF329) Zn_Tnp_IS1595 PF12760.2 AEO63795.1 - 6.3 6.7 5.6 17 5.2 0.4 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Ank_2 PF12796.2 AEO63796.1 - 1.9e-26 92.2 0.0 2.4e-13 50.2 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 AEO63796.1 - 2.7e-25 86.8 6.7 5.9e-11 41.6 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 AEO63796.1 - 7.6e-25 86.3 1.5 3.9e-12 45.9 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO63796.1 - 3.8e-21 73.0 2.0 2e-08 33.6 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 AEO63796.1 - 2.1e-16 59.9 0.2 8.5e-07 29.3 0.0 4.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Keratin_B2 PF01500.12 AEO63797.1 - 0.27 10.9 5.6 0.072 12.8 0.8 1.9 2 0 0 2 2 2 0 Keratin, high sulfur B2 protein Collagen PF01391.13 AEO63798.1 - 2.7e-05 23.5 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Rab5ip PF07019.7 AEO63798.1 - 0.16 12.1 16.7 5.1e+02 0.8 11.6 2.6 1 1 0 1 1 1 0 Rab5-interacting protein (Rab5ip) DUF726 PF05277.7 AEO63798.1 - 6 5.6 11.5 6.9 5.4 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) GILT PF03227.11 AEO63799.1 - 0.18 11.6 1.9 11 5.8 0.1 2.2 2 0 0 2 2 2 0 Gamma interferon inducible lysosomal thiol reductase (GILT) Fer4_4 PF12800.2 AEO63799.1 - 0.83 10.1 11.7 2.9 8.4 0.8 2.6 3 0 0 3 3 3 0 4Fe-4S binding domain TNFR_c6 PF00020.13 AEO63799.1 - 3 8.0 12.6 1.5 8.9 0.7 2.5 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region EndIII_4Fe-2S PF10576.4 AEO63799.1 - 3.3 8.0 11.0 4.1 7.7 0.6 3.0 3 0 0 3 3 3 0 Iron-sulfur binding domain of endonuclease III Fer4_17 PF13534.1 AEO63799.1 - 7.9 6.9 10.4 40 4.6 7.3 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Cytadhesin_P30 PF07271.6 AEO63799.1 - 8.7 5.5 9.6 9.3 5.4 6.6 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF1996 PF09362.5 AEO63800.1 - 4e-94 314.6 0.4 5.6e-94 314.1 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SnoaL PF07366.7 AEO63802.1 - 0.021 14.3 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 AEO63802.1 - 0.027 14.8 0.1 0.048 14.0 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain DUF2457 PF10446.4 AEO63802.1 - 0.54 8.9 3.0 0.68 8.5 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 AEO63802.1 - 1.8 7.7 4.5 2.5 7.3 3.1 1.1 1 0 0 1 1 1 0 NOA36 protein tRNA-synt_2 PF00152.15 AEO63804.1 - 3.3e-73 246.3 0.0 5.1e-73 245.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 AEO63804.1 - 1.1e-23 83.5 0.0 1.8e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 AEO63804.1 - 3.4e-07 30.0 0.0 7.6e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AEO63804.1 - 0.0064 15.7 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Abhydrolase_3 PF07859.8 AEO63805.1 - 4.9e-41 140.6 0.0 6.2e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 AEO63805.1 - 8.9e-06 24.6 0.0 1.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 AEO63805.1 - 0.026 14.2 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 AEO63805.1 - 0.058 12.7 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF504 PF04457.7 AEO63805.1 - 0.1 12.8 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF504) Peptidase_S13 PF02113.10 AEO63807.1 - 0.13 10.7 0.0 0.37 9.2 0.0 1.6 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family GMC_oxred_N PF00732.14 AEO63808.1 - 1.7e-52 178.4 0.0 3e-52 177.6 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO63808.1 - 1.3e-33 116.3 0.0 2.4e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 AEO63808.1 - 1.5e-08 33.8 0.2 1.1e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 AEO63808.1 - 1.4e-07 30.7 0.4 0.00011 21.2 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AEO63808.1 - 6.8e-05 23.0 0.1 0.01 15.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO63808.1 - 0.00034 20.5 0.0 0.0085 15.9 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO63808.1 - 0.00082 17.9 0.1 0.11 10.9 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 AEO63808.1 - 0.003 17.5 0.1 0.0085 16.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 AEO63808.1 - 0.035 13.0 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 AEO63808.1 - 0.069 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.14 AEO63808.1 - 0.083 11.9 0.3 0.17 10.8 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.11 AEO63809.1 - 2.6e-30 105.3 34.9 2.6e-30 105.3 24.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 AEO63809.1 - 0.0074 16.0 0.1 0.0074 16.0 0.1 2.4 3 0 0 3 3 3 1 MFS_1 like family RCC1 PF00415.13 AEO63814.1 - 8.1e-62 205.2 19.0 1.4e-11 44.3 0.1 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AEO63814.1 - 3.1e-42 141.3 37.4 3.8e-09 35.9 0.1 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat LtrA PF06772.6 AEO63815.1 - 7.4e-08 31.6 5.1 9.1e-08 31.3 3.6 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) MutS_IV PF05190.13 AEO63815.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 MutS family domain IV LtrA PF06772.6 AEO63816.1 - 1.4e-09 37.3 1.2 2e-09 36.8 0.8 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF2530 PF10745.4 AEO63818.1 - 0.89 9.5 6.1 0.91 9.5 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) DUF805 PF05656.9 AEO63818.1 - 2 8.2 10.4 0.85 9.4 1.9 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF805) Gemini_mov PF01708.11 AEO63818.1 - 3.9 7.0 8.1 2.6 7.6 1.0 2.5 2 0 0 2 2 2 0 Geminivirus putative movement protein Ank PF00023.25 AEO63822.1 - 2e-15 55.7 0.0 8e-05 22.2 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 AEO63822.1 - 5e-15 55.6 0.0 1e-07 32.1 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AEO63822.1 - 2.5e-10 39.5 0.0 0.008 16.3 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 AEO63822.1 - 2.5e-06 27.5 0.0 0.0054 16.9 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO63822.1 - 7.9e-05 23.0 0.0 4.5 7.9 0.0 4.4 4 1 1 5 5 5 2 Ankyrin repeats (many copies) F-box-like PF12937.2 AEO63822.1 - 0.85 9.4 7.2 0.054 13.2 0.7 2.2 3 0 0 3 3 3 0 F-box-like 2-Hacid_dh_C PF02826.14 AEO63823.1 - 2e-44 150.8 0.0 2.6e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AEO63823.1 - 7e-06 25.5 0.0 1.6e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 AEO63823.1 - 0.0092 16.3 0.0 0.021 15.1 0.0 1.6 2 0 0 2 2 2 1 XdhC Rossmann domain ELFV_dehydrog PF00208.16 AEO63823.1 - 0.043 13.3 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.1 AEO63823.1 - 0.097 12.6 0.4 0.25 11.3 0.1 1.8 2 0 0 2 2 2 0 NADH(P)-binding Methyltransf_2 PF00891.13 AEO63824.1 - 3.3e-28 98.5 0.0 4.2e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Phage_X PF05155.10 AEO63825.1 - 0.062 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Phage X family Cupin_2 PF07883.6 AEO63826.1 - 1.7e-13 49.8 0.1 2.1e-09 36.7 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 AEO63826.1 - 0.0043 16.4 0.0 0.3 10.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 AEO63826.1 - 0.014 15.1 0.0 0.067 12.8 0.0 2.1 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_4 PF08007.7 AEO63826.1 - 0.024 13.8 0.4 0.064 12.4 0.0 1.7 2 0 0 2 2 2 0 Cupin superfamily protein DUF1255 PF06865.6 AEO63826.1 - 0.064 13.5 0.0 0.29 11.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1255) Abhydrolase_3 PF07859.8 AEO63827.1 - 3.1e-15 56.3 0.1 2.6e-09 36.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AEO63827.1 - 2.5e-09 36.6 0.0 1.6e-06 27.5 0.0 2.8 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 AEO63827.1 - 3.1e-08 33.7 0.1 4.3e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO63827.1 - 3.7e-08 33.2 0.0 6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 AEO63827.1 - 9.1e-08 31.8 0.0 0.0023 17.3 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase COesterase PF00135.23 AEO63827.1 - 0.0038 16.0 0.1 0.0082 14.8 0.0 1.5 2 0 0 2 2 2 1 Carboxylesterase family DLH PF01738.13 AEO63827.1 - 0.0086 15.3 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family LIP PF03583.9 AEO63827.1 - 0.027 13.6 0.1 0.18 10.9 0.0 2.3 3 0 0 3 3 3 0 Secretory lipase Abhydrolase_1 PF00561.15 AEO63827.1 - 0.11 12.0 0.0 0.38 10.2 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Fungal_trans PF04082.13 AEO63828.1 - 5.9e-11 41.7 0.4 5.2e-10 38.6 0.0 2.6 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO63828.1 - 8.6e-05 22.3 6.3 0.00021 21.1 4.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.13 AEO63829.1 - 0.0058 16.3 1.3 0.012 15.3 0.9 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF1875 PF08961.5 AEO63829.1 - 0.017 14.4 0.3 0.039 13.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) DUF904 PF06005.7 AEO63829.1 - 0.081 13.2 0.3 0.21 11.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) IncA PF04156.9 AEO63829.1 - 1.2 8.6 6.7 2 7.9 4.6 1.2 1 0 0 1 1 1 0 IncA protein SAICAR_synt PF01259.13 AEO63830.1 - 3.2e-79 265.5 0.0 4.1e-79 265.2 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase RTA1 PF04479.8 AEO63831.1 - 4.8e-42 143.9 1.0 7.5e-42 143.3 0.7 1.3 1 0 0 1 1 1 1 RTA1 like protein EthD PF07110.6 AEO63832.1 - 2e-06 28.6 0.0 2.7e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 EthD domain HEAT_EZ PF13513.1 AEO63833.1 - 3.9e-19 68.5 18.1 2.1e-06 28.0 0.0 11.8 11 2 3 14 14 14 5 HEAT-like repeat HEAT PF02985.17 AEO63833.1 - 2.2e-14 52.1 5.8 0.003 17.5 0.0 9.1 12 0 0 12 12 10 3 HEAT repeat HEAT_2 PF13646.1 AEO63833.1 - 9.3e-12 45.0 26.9 0.00088 19.5 0.2 9.5 3 2 7 10 10 10 5 HEAT repeats IBN_N PF03810.14 AEO63833.1 - 2.5e-08 33.6 1.8 1.8e-07 30.9 0.3 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 AEO63833.1 - 1.4e-07 31.8 0.1 0.84 10.0 0.0 5.6 4 2 1 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 AEO63833.1 - 1.4e-05 24.5 0.2 0.0014 18.0 0.0 3.8 4 1 0 4 4 4 1 CLASP N terminal ParcG PF10274.4 AEO63833.1 - 0.0012 18.8 0.8 0.15 11.9 0.0 3.9 3 1 1 4 4 4 1 Parkin co-regulated protein Cnd1 PF12717.2 AEO63833.1 - 0.006 16.4 1.4 7.3 6.3 0.0 4.5 3 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 AEO63833.1 - 0.022 14.3 0.0 0.77 9.3 0.0 3.0 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) DUF2435 PF10363.4 AEO63833.1 - 0.036 13.9 2.5 2.2 8.2 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) RNA_pol_3_Rpc31 PF11705.3 AEO63833.1 - 0.29 11.0 5.8 0.78 9.6 4.0 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1996 PF09362.5 AEO63835.1 - 6e-91 304.2 0.3 7.3e-91 303.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Mucin PF01456.12 AEO63836.1 - 1.9 8.2 9.3 2.7 7.7 6.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein 4HBT PF03061.17 AEO63838.1 - 9.2e-16 57.7 0.4 1.5e-15 57.0 0.3 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 AEO63838.1 - 0.012 16.1 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF4442 PF14539.1 AEO63838.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Acetyltransf_1 PF00583.19 AEO63839.1 - 4.2e-11 42.7 0.1 8.7e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO63839.1 - 1.6e-07 31.3 0.0 2.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO63839.1 - 0.00011 22.2 0.1 0.00024 21.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AEO63839.1 - 0.0012 18.7 0.1 0.0044 16.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO63839.1 - 0.0017 18.2 0.3 0.31 10.8 0.1 2.5 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AEO63839.1 - 0.0018 18.2 0.0 0.0042 17.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.1 AEO63840.1 - 1.2e-60 205.2 47.6 1.5e-60 204.9 33.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO63840.1 - 3e-15 55.5 44.1 3.8e-15 55.1 30.6 1.1 1 0 0 1 1 1 1 Amino acid permease Pectate_lyase_3 PF12708.2 AEO63842.1 - 2.3e-81 273.2 25.6 1.9e-67 227.7 3.4 4.3 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 AEO63842.1 - 4.1e-07 29.3 1.8 0.012 15.0 0.0 3.0 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DUF3716 PF12511.3 AEO63843.1 - 1.7e-10 40.3 3.9 2.7e-10 39.7 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF4332 PF14229.1 AEO63843.1 - 0.047 13.6 0.4 0.091 12.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Synthase_beta PF11421.3 AEO63844.1 - 3.6 8.3 9.6 3.1 8.5 3.5 2.5 2 0 0 2 2 2 0 ATP synthase F1 beta subunit DUF1996 PF09362.5 AEO63845.1 - 1.8e-89 299.4 2.1 2.3e-89 299.1 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Nuc_sug_transp PF04142.10 AEO63848.1 - 3.2e-81 272.0 5.1 4.6e-81 271.5 3.5 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 AEO63848.1 - 4e-09 35.8 9.3 4.1e-08 32.4 6.5 2.0 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 AEO63848.1 - 6.6e-07 29.0 21.4 0.00061 19.4 7.8 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 AEO63848.1 - 2.2e-06 27.7 23.2 6.9e-05 22.8 3.0 2.8 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 AEO63848.1 - 9.8e-06 25.7 11.1 0.0011 19.1 0.8 2.5 2 0 0 2 2 2 2 Multidrug resistance efflux transporter BTB PF00651.26 AEO63849.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.4 1 1 0 1 1 1 0 BTB/POZ domain Sec63 PF02889.11 AEO63851.1 - 9e-41 140.1 0.0 1.3e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 AEO63851.1 - 2.9e-27 95.2 0.1 1.2e-26 93.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO63851.1 - 3.3e-10 39.6 0.0 3.6e-09 36.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO63851.1 - 5.9e-09 36.0 0.0 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 AEO63851.1 - 0.0015 17.9 0.0 0.054 12.7 0.0 2.6 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain HHH_5 PF14520.1 AEO63851.1 - 0.0035 17.4 0.0 0.017 15.2 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain T2SE PF00437.15 AEO63851.1 - 0.0053 15.7 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 AEO63851.1 - 0.006 16.3 0.0 0.042 13.5 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 AEO63851.1 - 0.009 16.1 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 AEO63851.1 - 0.1 12.0 0.0 1.9 7.8 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain MFS_1 PF07690.11 AEO63852.1 - 4.7e-24 84.7 36.4 4.7e-24 84.7 25.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily GFO_IDH_MocA PF01408.17 AEO63853.1 - 3e-16 60.0 0.1 6.6e-16 58.9 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 AEO63853.1 - 0.00019 21.1 0.0 0.00046 19.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Saccharop_dh PF03435.13 AEO63853.1 - 0.022 13.7 0.1 0.04 12.8 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Zn_clus PF00172.13 AEO63854.1 - 0.00084 19.2 10.3 0.0016 18.3 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2360 PF10152.4 AEO63854.1 - 0.12 12.6 2.1 0.27 11.4 1.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) MFS_1 PF07690.11 AEO63855.1 - 5e-31 107.7 42.3 1.8e-29 102.5 29.3 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO63855.1 - 4.8e-12 45.1 3.5 4.8e-12 45.1 2.4 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 AEO63855.1 - 2.2e-10 39.3 14.4 1.7e-08 33.1 5.7 2.0 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF4153 PF13687.1 AEO63855.1 - 0.17 11.4 10.4 0.5 9.8 7.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4153) Phage_holin_2 PF04550.7 AEO63855.1 - 2.2 8.4 5.7 2.2 8.4 0.9 2.9 2 0 0 2 2 2 0 Phage holin family 2 FAD_binding_3 PF01494.14 AEO63856.1 - 9.6e-17 61.0 2.0 4.8e-16 58.7 1.4 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 AEO63856.1 - 0.035 13.8 0.1 0.58 9.9 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 AEO63856.1 - 0.054 13.5 1.1 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Semialdhyde_dh PF01118.19 AEO63856.1 - 0.082 13.2 0.1 0.59 10.4 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain SE PF08491.5 AEO63856.1 - 0.17 10.6 0.0 0.63 8.8 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase Ank_2 PF12796.2 AEO63858.1 - 4.5e-22 78.1 0.0 1.3e-13 51.1 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AEO63858.1 - 3.4e-19 67.6 1.6 4.7e-07 29.2 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 AEO63858.1 - 1e-16 60.5 0.1 1.1e-08 35.0 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO63858.1 - 6.1e-16 58.4 0.1 8.6e-08 32.4 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO63858.1 - 1.5e-15 55.7 0.0 0.00021 21.2 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat Cyclase PF04199.8 AEO63858.1 - 0.078 12.6 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Putative cyclase Peptidase_M3 PF01432.15 AEO63859.1 - 1.1e-89 301.6 0.0 1.5e-89 301.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 DUF2046 PF09755.4 AEO63859.1 - 0.093 11.6 0.3 0.17 10.7 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Mito_fiss_reg PF05308.6 AEO63859.1 - 0.97 8.7 6.5 11 5.3 3.6 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Tyrosinase PF00264.15 AEO63860.1 - 5.4e-36 124.8 0.6 6.6e-36 124.5 0.4 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase E1_DerP2_DerF2 PF02221.10 AEO63862.1 - 0.061 13.5 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 ML domain Serglycin PF04360.7 AEO63862.1 - 3.5 7.3 36.8 9.9 5.8 14.1 2.6 1 1 1 2 2 2 0 Serglycin TFIIA PF03153.8 AEO63863.1 - 0.54 10.0 21.6 0.78 9.5 15.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LUC7 PF03194.10 AEO63864.1 - 2.4e-67 227.1 0.1 3e-67 226.8 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Occludin_ELL PF07303.8 AEO63864.1 - 0.045 14.4 0.6 0.31 11.8 0.1 2.2 2 0 0 2 2 2 0 Occludin homology domain DUF1241 PF06840.6 AEO63864.1 - 0.14 11.4 0.1 7.4 5.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1241) Tropomyosin_1 PF12718.2 AEO63864.1 - 0.71 9.7 4.0 2.5 7.9 2.8 1.7 1 1 0 1 1 1 0 Tropomyosin like Gpi16 PF04113.9 AEO63865.1 - 1.1e-248 825.9 0.0 1.3e-248 825.6 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component FUSC PF04632.7 AEO63865.1 - 0.024 13.1 0.4 0.034 12.5 0.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3716 PF12511.3 AEO63866.1 - 1.2e-11 43.9 3.6 2.5e-11 43.0 2.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) MGC-24 PF05283.6 AEO63868.1 - 0.8 9.4 11.4 1 9.1 7.9 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Inh PF02974.9 AEO63869.1 - 0.035 13.6 0.2 0.052 13.1 0.1 1.4 1 1 0 1 1 1 0 Protease inhibitor Inh Nuc_deoxyrib_tr PF05014.10 AEO63870.1 - 0.0021 17.9 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase tRNA-synt_1e PF01406.14 AEO63871.1 - 6.3e-105 350.6 0.0 1.2e-104 349.6 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 AEO63871.1 - 9.8e-05 21.1 1.1 0.075 11.6 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.6 AEO63871.1 - 0.00038 20.6 0.0 0.0015 18.7 0.0 2.1 1 0 0 1 1 1 1 DALR domain tRNA-synt_1c PF00749.16 AEO63871.1 - 0.11 11.1 0.6 0.23 10.0 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain PAN_4 PF14295.1 AEO63872.1 - 5.9e-06 25.8 0.3 1.2e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 PAN domain SpoIIIAH PF12685.2 AEO63872.1 - 0.0091 15.5 0.2 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 SpoIIIAH-like protein Shisa PF13908.1 AEO63872.1 - 0.022 14.9 0.6 0.022 14.9 0.4 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF3357 PF11837.3 AEO63872.1 - 0.027 14.3 2.9 0.051 13.4 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) SoxE PF06525.6 AEO63872.1 - 1.3 8.2 8.6 0.11 11.7 1.7 2.1 2 0 0 2 2 2 0 Sulfocyanin (SoxE) VWA_2 PF13519.1 AEO63874.1 - 8.3e-05 22.7 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-C2H2_2 PF12756.2 AEO63874.1 - 4.1 7.5 9.0 0.8 9.8 1.5 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF1183 PF06682.7 AEO63875.1 - 0.0028 17.3 0.9 0.0028 17.3 0.6 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF1183) SKG6 PF08693.5 AEO63875.1 - 0.27 10.5 3.1 0.68 9.2 2.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Retinal PF15449.1 AEO63875.1 - 1.5 6.3 16.2 2.1 5.8 11.3 1.1 1 0 0 1 1 1 0 Retinal protein CytochromB561_N PF09786.4 AEO63875.1 - 6.5 5.0 13.0 9.2 4.5 9.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF605 PF04652.11 AEO63875.1 - 8.1 5.7 13.7 14 4.9 9.5 1.3 1 0 0 1 1 1 0 Vta1 like Pkinase_Tyr PF07714.12 AEO63876.1 - 4.9e-07 29.0 0.0 6.6e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 AEO63876.1 - 6.5e-07 28.7 0.0 7.8e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CcdA PF07362.7 AEO63876.1 - 0.13 12.1 0.3 0.23 11.3 0.2 1.4 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA Pkinase PF00069.20 AEO63877.1 - 1.9e-22 79.6 0.0 2.4e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO63877.1 - 1.6e-17 63.4 0.0 8.3e-17 61.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO63877.1 - 0.00041 20.1 1.6 0.0007 19.3 0.3 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 AEO63877.1 - 0.0017 17.3 0.0 0.0052 15.7 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 AEO63877.1 - 0.01 15.3 0.1 0.023 14.2 0.1 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 AEO63877.1 - 0.013 14.6 0.1 0.026 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 AEO63877.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 AEO63877.1 - 0.027 13.8 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 AEO63877.1 - 0.032 13.0 0.1 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF1510 PF07423.6 AEO63878.1 - 0.0026 17.1 7.9 0.0026 17.1 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) TEBP_beta PF07404.6 AEO63878.1 - 0.034 13.2 8.5 0.03 13.4 5.9 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Trypan_PARP PF05887.6 AEO63878.1 - 0.044 13.5 3.7 0.05 13.4 2.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NARP1 PF12569.3 AEO63878.1 - 0.072 11.8 8.8 0.08 11.6 6.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Protocadherin PF08374.6 AEO63878.1 - 0.082 12.5 5.0 0.091 12.3 3.5 1.1 1 0 0 1 1 1 0 Protocadherin Glypican PF01153.14 AEO63878.1 - 0.12 10.9 1.2 0.13 10.8 0.8 1.0 1 0 0 1 1 1 0 Glypican DUF3246 PF11596.3 AEO63878.1 - 0.17 11.1 6.6 0.2 10.9 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Ribosomal_60s PF00428.14 AEO63878.1 - 0.3 11.5 14.7 0.47 10.8 10.1 1.4 1 1 0 1 1 1 0 60s Acidic ribosomal protein DUF2201_N PF13203.1 AEO63878.1 - 0.3 10.2 3.9 0.33 10.0 2.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain SAPS PF04499.10 AEO63878.1 - 0.34 9.4 3.4 0.34 9.4 2.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TAF4 PF05236.9 AEO63878.1 - 0.36 10.0 8.2 0.33 10.2 5.0 1.3 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family FLO_LFY PF01698.11 AEO63878.1 - 0.41 9.4 6.1 0.42 9.4 4.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4337 PF14235.1 AEO63878.1 - 0.45 10.3 3.5 0.62 9.8 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) EBV-NA3 PF05009.7 AEO63878.1 - 0.49 9.6 2.0 0.52 9.5 1.4 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Vfa1 PF08432.5 AEO63878.1 - 1.1 9.3 14.9 1.3 9.0 10.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sec62 PF03839.11 AEO63878.1 - 1.9 7.8 7.3 2.2 7.6 5.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 OAD_gamma PF04277.8 AEO63878.1 - 2.4 8.6 8.4 4.3 7.7 5.8 1.7 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Tom22 PF04281.8 AEO63878.1 - 3.3 7.2 10.9 0.18 11.2 3.3 1.7 1 1 1 2 2 2 0 Mitochondrial import receptor subunit Tom22 RNA_polI_A34 PF08208.6 AEO63878.1 - 4 7.0 19.6 4.5 6.8 13.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NPR3 PF03666.8 AEO63878.1 - 4.9 5.5 6.6 5.2 5.4 4.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1764 PF08576.5 AEO63878.1 - 5.8 7.7 13.5 8.1 7.2 9.3 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) MRI PF15325.1 AEO63878.1 - 9.6 7.2 9.3 6.3 7.8 4.7 1.8 1 1 1 2 2 2 0 Modulator of retrovirus infection RVT_1 PF00078.22 AEO63879.1 - 0.00095 18.5 0.3 0.00095 18.5 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LAMTOR PF15454.1 AEO63880.1 - 2.5e-17 62.9 0.6 4.2e-17 62.1 0.4 1.4 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF964 PF06133.6 AEO63880.1 - 0.00083 19.3 2.2 0.0015 18.5 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF964) PCYCGC PF13798.1 AEO63880.1 - 0.08 12.6 0.1 0.084 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif FlaC_arch PF05377.6 AEO63880.1 - 0.12 12.2 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) zf-C2H2_jaz PF12171.3 AEO63884.1 - 0.029 14.5 0.1 0.044 13.9 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 AEO63884.1 - 0.11 12.5 0.2 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF1974 PF09317.6 AEO63884.1 - 0.13 11.6 1.5 0.2 10.9 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) zf-met PF12874.2 AEO63884.1 - 0.15 12.3 0.2 0.23 11.7 0.2 1.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Med7 PF05983.6 AEO63885.1 - 5.3e-49 166.1 0.1 6.2e-49 165.8 0.1 1.0 1 0 0 1 1 1 1 MED7 protein DUF1759 PF03564.10 AEO63885.1 - 0.038 13.8 0.2 0.76 9.5 0.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1759) Cytochrome-c551 PF10643.4 AEO63886.1 - 0.016 14.4 2.0 0.022 14.0 1.4 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Phage_GPD PF05954.6 AEO63886.1 - 0.13 11.4 5.3 0.15 11.2 3.7 1.1 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Pol_alpha_B_N PF08418.5 AEO63886.1 - 0.16 11.5 8.7 0.19 11.2 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal TFIIA PF03153.8 AEO63886.1 - 0.81 9.5 4.2 0.77 9.5 2.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MSA-2c PF12238.3 AEO63886.1 - 4.4 6.9 9.3 6.1 6.4 6.4 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c MAP65_ASE1 PF03999.7 AEO63886.1 - 4.9 5.6 17.0 6.3 5.2 11.8 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) TFIIS_M PF07500.9 AEO63887.1 - 2.8e-18 66.0 0.1 2.8e-18 66.0 0.1 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 AEO63887.1 - 6.5e-18 65.3 0.0 1.4e-17 64.2 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 AEO63887.1 - 2.2e-09 36.8 8.2 4.5e-09 35.8 5.7 1.6 1 0 0 1 1 1 1 PHD-finger Proteasome PF00227.21 AEO63888.1 - 1.2e-60 204.1 0.1 1.5e-60 203.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AEO63888.1 - 1.7e-14 52.8 0.2 4.1e-14 51.5 0.2 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 AEO63888.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit PAP2 PF01569.16 AEO63889.1 - 1.1e-21 76.8 0.1 1.1e-21 76.8 0.1 1.8 2 0 0 2 2 2 1 PAP2 superfamily WD40 PF00400.27 AEO63890.1 - 7e-55 181.0 17.4 7.2e-09 35.2 0.0 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 AEO63890.1 - 1.8e-13 49.9 0.7 3.9e-13 48.9 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO63890.1 - 1.3e-12 47.0 1.6 4e-12 45.4 1.0 2.0 1 1 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 AEO63890.1 - 0.00065 19.2 1.4 0.15 11.5 0.4 3.2 1 1 1 2 2 2 2 PQQ-like domain PRANC PF09372.5 AEO63890.1 - 0.008 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 PRANC domain CDtoxinA PF03498.9 AEO63890.1 - 0.042 13.2 0.2 7.7 5.8 0.0 2.7 1 1 1 2 2 2 0 Cytolethal distending toxin A/C family CPSF_A PF03178.10 AEO63890.1 - 0.14 11.1 0.1 1.6 7.7 0.0 2.4 3 0 0 3 3 3 0 CPSF A subunit region HORMA PF02301.13 AEO63891.1 - 0.0022 17.5 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 HORMA domain Dynamin_N PF00350.18 AEO63892.1 - 1.3e-23 83.6 0.0 1.2e-22 80.4 0.0 2.5 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 AEO63892.1 - 9.4e-10 37.7 0.1 2.7e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 AEO63892.1 - 0.002 18.0 0.0 0.01 15.7 0.0 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 AEO63892.1 - 0.0087 16.0 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.1 AEO63892.1 - 0.015 15.3 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 AEO63892.1 - 0.015 15.7 0.0 0.052 14.0 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 AEO63892.1 - 0.029 13.8 0.1 0.07 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 AEO63892.1 - 0.042 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 AEO63892.1 - 0.24 10.6 0.0 11 5.2 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B NTP_transferase PF00483.18 AEO63893.1 - 1.6e-29 102.9 0.0 2.1e-29 102.5 0.0 1.3 1 1 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 AEO63893.1 - 5.4e-09 35.1 4.5 0.00026 20.3 0.0 3.8 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 AEO63893.1 - 5.9e-07 29.7 0.0 8.9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 AEO63893.1 - 0.0089 15.5 0.0 0.023 14.1 0.0 1.6 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase MARVEL PF01284.18 AEO63894.1 - 5.7e-05 22.9 15.9 0.00022 21.0 11.1 1.8 1 1 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.7 AEO63894.1 - 0.0025 17.4 2.8 0.0049 16.4 1.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF588) Peptidase_M56 PF05569.6 AEO63894.1 - 0.033 13.1 0.3 0.033 13.1 0.2 1.5 2 0 0 2 2 2 0 BlaR1 peptidase M56 Vma12 PF11712.3 AEO63894.1 - 0.035 13.8 0.1 0.063 12.9 0.1 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PIR PF00399.14 AEO63895.1 - 7.3 6.1 9.1 5.4 6.5 0.1 3.3 3 0 0 3 3 3 0 Yeast PIR protein repeat HTH_35 PF13693.1 AEO63896.1 - 0.032 13.9 3.4 14 5.5 0.0 3.6 1 1 3 4 4 4 0 Winged helix-turn-helix DNA-binding SARA PF11409.3 AEO63896.1 - 0.075 12.9 0.0 5.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Smad anchor for receptor activation (SARA) SLT_beta PF02258.11 AEO63896.1 - 0.11 12.3 0.0 7.7 6.4 0.0 2.6 1 1 2 3 3 3 0 Shiga-like toxin beta subunit zf-U1 PF06220.7 AEO63897.1 - 6.8e-08 31.9 0.5 1e-07 31.3 0.4 1.3 1 0 0 1 1 1 1 U1 zinc finger DUF2951 PF11166.3 AEO63897.1 - 1.1 9.1 4.2 2.3 8.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) GAGA_bind PF06217.7 AEO63897.1 - 3.8 7.3 7.3 0.86 9.5 2.1 1.9 1 1 1 2 2 2 0 GAGA binding protein-like family Ank_2 PF12796.2 AEO63898.1 - 9.1e-28 96.4 0.0 1.6e-08 34.8 0.0 5.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 AEO63898.1 - 7.5e-22 75.9 12.8 2.1e-06 27.2 0.1 9.0 10 1 0 10 10 10 4 Ankyrin repeat Ank_3 PF13606.1 AEO63898.1 - 4.6e-19 66.5 0.3 0.00046 20.1 0.1 7.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 AEO63898.1 - 4.8e-18 65.1 0.0 0.00012 22.5 0.1 6.6 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO63898.1 - 2.9e-14 52.7 9.5 0.021 15.0 0.5 8.0 4 2 3 7 7 7 4 Ankyrin repeats (many copies) F-box-like PF12937.2 AEO63898.1 - 2.8e-06 26.9 1.6 1.2e-05 24.9 1.1 2.1 1 0 0 1 1 1 1 F-box-like Telomere_Sde2_2 PF13297.1 AEO63898.1 - 0.098 11.9 0.4 0.24 10.7 0.3 1.6 1 0 0 1 1 1 0 Telomere stability C-terminal Cutinase PF01083.17 AEO63899.1 - 1.1e-06 28.5 0.0 1.3e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.2 AEO63900.1 - 6.8e-17 62.1 3.6 9.6e-17 61.6 2.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO63900.1 - 5.3e-08 32.7 0.8 1.2e-07 31.5 0.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AEO63900.1 - 0.0019 17.9 0.1 0.0041 16.9 0.1 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Sugar_tr PF00083.19 AEO63901.1 - 1.5e-82 277.6 20.4 1.8e-82 277.3 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO63901.1 - 1.6e-29 102.7 22.8 2.4e-29 102.1 15.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 AEO63901.1 - 0.00013 20.5 2.1 0.00013 20.5 1.5 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein Nefa_Nip30_N PF10187.4 AEO63903.1 - 0.14 12.3 3.8 6.6 6.9 0.1 2.3 1 1 1 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Glycos_transf_1 PF00534.15 AEO63904.1 - 2.4e-10 40.0 0.0 9.7e-10 38.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AEO63904.1 - 1.7e-08 34.6 0.0 3.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 G-alpha PF00503.15 AEO63905.1 - 1.2e-72 244.8 0.0 1.5e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 AEO63905.1 - 9.2e-09 34.7 0.7 0.00011 21.5 0.0 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 AEO63905.1 - 2.1e-05 24.4 0.1 0.00054 19.8 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 AEO63905.1 - 0.00028 20.3 0.0 0.00056 19.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 AEO63905.1 - 0.00031 21.2 0.0 0.072 13.5 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 AEO63905.1 - 0.0013 19.1 0.1 0.002 18.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 AEO63905.1 - 0.021 14.0 0.1 3 7.0 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.13 AEO63905.1 - 0.023 14.1 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 AEO63905.1 - 0.044 14.0 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 AEO63905.1 - 0.13 11.6 0.0 0.41 10.0 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AEO63905.1 - 0.21 10.6 0.9 3.3 6.7 0.4 2.2 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Sugar_tr PF00083.19 AEO63906.1 - 2.7e-84 283.3 16.9 3.2e-84 283.0 11.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO63906.1 - 2.6e-26 92.1 21.9 2.6e-26 92.1 15.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO63906.1 - 7.3e-08 31.0 1.3 1.1e-07 30.4 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Asp PF00026.18 AEO63907.1 - 2.8e-61 207.5 0.0 3.4e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 AEO63907.1 - 2.4e-07 30.4 0.0 5.7e-06 25.9 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 AEO63907.1 - 6.3e-07 29.4 1.2 1.9e-05 24.6 0.0 3.1 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO63907.1 - 0.00091 19.6 0.6 0.25 11.8 0.1 3.6 3 1 0 3 3 3 1 Aspartyl protease AMP-binding PF00501.23 AEO63908.1 - 2.6e-86 289.6 0.0 7.5e-86 288.1 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.21 AEO63908.1 - 4.5e-78 262.2 2.2 1.2e-77 260.8 0.0 2.8 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 AEO63908.1 - 6.7e-54 183.0 0.9 1.3e-53 182.0 0.7 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 AEO63908.1 - 5.3e-53 180.4 0.0 1.8e-52 178.6 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 AEO63908.1 - 7.5e-50 169.1 4.5 7.8e-48 162.5 0.2 2.8 2 0 0 2 2 2 2 KR domain adh_short PF00106.20 AEO63908.1 - 2.1e-46 157.8 9.9 4.6e-41 140.5 0.0 3.2 3 0 0 3 3 2 2 short chain dehydrogenase Condensation PF00668.15 AEO63908.1 - 2.4e-41 141.5 0.0 4e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.7 AEO63908.1 - 2e-37 128.4 0.0 4.2e-37 127.4 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 AEO63908.1 - 1.1e-31 109.0 0.0 5.1e-31 106.9 0.0 2.3 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 AEO63908.1 - 3.8e-18 65.7 0.0 1.6e-17 63.8 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO63908.1 - 1.4e-15 57.8 0.0 3.7e-10 40.3 0.0 4.6 4 0 0 4 4 3 2 Methyltransferase domain PP-binding PF00550.20 AEO63908.1 - 1.7e-15 56.9 0.6 3.3e-10 40.0 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 AEO63908.1 - 6e-15 55.3 0.0 1.9e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO63908.1 - 1.2e-13 51.2 0.0 3.5e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO63908.1 - 1.7e-12 47.1 0.0 3.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 AEO63908.1 - 1.3e-11 44.4 0.0 3e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HxxPF_rpt PF13745.1 AEO63908.1 - 3e-10 40.2 0.0 7.7e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain Ubie_methyltran PF01209.13 AEO63908.1 - 7.9e-08 31.6 0.0 1.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 AEO63908.1 - 3.8e-06 26.1 0.0 7.7e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 AEO63908.1 - 4.3e-05 22.3 0.0 8.5e-05 21.3 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 AEO63908.1 - 8.3e-05 22.8 0.0 0.00037 20.8 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain RmlD_sub_bind PF04321.12 AEO63908.1 - 0.00066 18.6 0.3 0.0016 17.3 0.2 1.7 1 0 0 1 1 1 1 RmlD substrate binding domain Methyltransf_16 PF10294.4 AEO63908.1 - 0.0014 18.1 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Semialdhyde_dh PF01118.19 AEO63908.1 - 0.012 15.8 0.1 0.052 13.8 0.1 2.1 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_8 PF05148.10 AEO63908.1 - 0.025 14.2 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase NmrA PF05368.8 AEO63908.1 - 0.053 12.7 0.4 0.53 9.4 0.1 2.7 3 0 0 3 3 3 0 NmrA-like family NodS PF05401.6 AEO63908.1 - 0.068 12.5 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 Nodulation protein S (NodS) RrnaAD PF00398.15 AEO63908.1 - 0.22 10.5 0.0 0.51 9.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GOLD_2 PF13897.1 AEO63908.1 - 0.29 11.3 0.2 0.76 10.0 0.2 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking NNMT_PNMT_TEMT PF01234.12 AEO63908.1 - 0.33 9.8 0.0 0.73 8.7 0.0 1.5 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Zn_clus PF00172.13 AEO63910.1 - 1.6e-06 27.8 6.9 2.6e-06 27.2 4.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 AEO63911.1 - 1.7e-09 37.8 1.4 1.2e-07 31.8 0.1 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO63911.1 - 8.1e-09 35.3 0.0 2.2e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 AEO63911.1 - 1.2e-07 30.6 0.0 1.7e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) AXE1 PF05448.7 AEO63911.1 - 0.0003 19.3 0.0 0.0011 17.5 0.0 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 AEO63911.1 - 0.025 13.7 0.1 0.098 11.8 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family ADH_zinc_N PF00107.21 AEO63914.1 - 1.2e-10 41.0 0.0 2.1e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO63914.1 - 1.8e-06 27.6 0.1 7.5e-06 25.6 0.1 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 AEO63916.1 - 2.6e-36 125.0 50.8 2.6e-36 125.0 35.2 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO63916.1 - 3.7e-12 45.5 14.7 3.7e-12 45.5 10.2 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 AEO63916.1 - 1.4e-08 33.3 24.4 2e-08 32.9 16.9 1.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 AEO63916.1 - 0.022 12.8 9.5 0.05 11.6 1.4 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Phosphoprotein PF00922.12 AEO63917.1 - 0.17 11.1 3.4 0.3 10.2 2.3 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein ArsB PF02040.10 AEO63918.1 - 1.2e-14 54.0 21.4 1.2e-10 41.0 5.8 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein MFMR PF07777.6 AEO63919.1 - 0.18 11.6 1.4 0.25 11.2 1.0 1.4 1 1 0 1 1 1 0 G-box binding protein MFMR Mucin PF01456.12 AEO63919.1 - 1.3 8.7 11.2 0.17 11.6 4.9 1.7 1 1 1 2 2 2 0 Mucin-like glycoprotein MS_channel PF00924.13 AEO63921.1 - 9.6e-12 44.6 0.0 1.9e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel TatC PF00902.13 AEO63921.1 - 1.4 8.2 16.6 0.069 12.5 7.4 1.8 2 0 0 2 2 2 0 Sec-independent protein translocase protein (TatC) Carb_anhydrase PF00194.16 AEO63923.1 - 8.8e-17 60.9 0.0 1.3e-08 34.1 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase GMC_oxred_C PF05199.8 AEO63927.1 - 2.9e-32 111.9 0.0 5.8e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 AEO63927.1 - 7.2e-32 110.7 0.0 4.4e-29 101.5 0.0 2.7 1 1 1 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 AEO63927.1 - 0.00063 19.7 0.1 0.0021 18.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO63927.1 - 0.00065 18.7 0.1 0.0066 15.3 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AEO63927.1 - 0.018 14.8 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO63927.1 - 0.056 11.9 0.2 0.081 11.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 AEO63927.1 - 0.068 12.2 0.4 0.098 11.6 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 AEO63927.1 - 0.069 11.9 0.2 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 AEO63927.1 - 0.079 11.8 0.5 0.11 11.3 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Glyco_hydro_25 PF01183.15 AEO63930.1 - 7.6e-42 143.1 0.1 8.7e-42 142.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 MFS_1 PF07690.11 AEO63931.1 - 4.4e-40 137.4 46.4 4.4e-40 137.4 32.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 AEO63932.1 - 8.8e-12 44.4 0.0 1.5e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO63932.1 - 1.6e-07 31.1 9.5 1.6e-07 31.1 6.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.18 AEO63933.1 - 1.9e-16 60.5 0.4 4.3e-16 59.3 0.3 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 AEO63933.1 - 6e-06 25.7 0.0 0.091 12.0 0.1 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 AEO63933.1 - 5.1e-05 22.9 0.0 0.00018 21.1 0.0 1.8 2 1 1 3 3 3 1 Choline/ethanolamine kinase EcKinase PF02958.15 AEO63933.1 - 0.002 17.3 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 AEO63933.1 - 0.044 12.4 0.0 0.065 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) p450 PF00067.17 AEO63934.1 - 1.6e-23 82.9 0.0 3.2e-23 81.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 SKG6 PF08693.5 AEO63935.1 - 0.069 12.4 0.7 0.13 11.6 0.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain NAD_binding_10 PF13460.1 AEO63936.1 - 3.2e-12 46.8 0.2 4.4e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 AEO63936.1 - 0.00034 19.9 0.0 0.77 8.9 0.0 2.3 2 1 0 2 2 2 2 NmrA-like family PC4 PF02229.11 AEO63936.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) Phytase-like PF13449.1 AEO63937.1 - 2.1e-28 99.5 0.2 5.8e-28 98.1 0.0 1.8 2 1 0 2 2 2 1 Esterase-like activity of phytase SdiA-regulated PF06977.6 AEO63937.1 - 0.076 11.9 0.0 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 SdiA-regulated Flavodoxin_NdrI PF07972.6 AEO63937.1 - 0.077 12.9 0.1 0.22 11.4 0.1 1.8 1 0 0 1 1 1 0 NrdI Flavodoxin like Chitin_bind_1 PF00187.14 AEO63938.1 - 0.13 12.2 24.8 0.16 11.9 15.9 2.0 1 1 1 2 2 2 0 Chitin recognition protein Peptidase_M20 PF01546.23 AEO63939.1 - 3.5e-23 82.0 0.0 9.9e-23 80.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 AEO63939.1 - 3.4e-19 67.9 2.6 0.0003 20.5 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat M20_dimer PF07687.9 AEO63939.1 - 2.1e-08 33.8 0.0 4.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 AEO63939.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 DUF2071 PF09844.4 AEO63939.1 - 0.038 13.3 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (COG2071) DUF3639 PF12341.3 AEO63939.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) PQQ_3 PF13570.1 AEO63939.1 - 0.085 13.1 0.5 6.6 7.1 0.0 3.9 3 0 0 3 3 3 0 PQQ-like domain CNH PF00780.17 AEO63939.1 - 0.19 11.1 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 CNH domain Tim17 PF02466.14 AEO63940.1 - 3e-32 111.3 7.6 3.3e-32 111.2 5.3 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Asparaginase_2 PF01112.13 AEO63941.1 - 3.3e-39 134.4 3.5 1.3e-18 66.8 0.0 3.4 3 0 0 3 3 3 3 Asparaginase WEMBL PF05701.6 AEO63943.1 - 2e-06 26.5 17.3 2.8e-06 26.1 12.0 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light MscS_porin PF12795.2 AEO63943.1 - 5.9e-05 22.5 17.7 0.00075 18.8 1.7 2.3 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain IncA PF04156.9 AEO63943.1 - 0.00049 19.7 6.9 0.00049 19.7 4.8 2.4 2 0 0 2 2 2 1 IncA protein DUF745 PF05335.8 AEO63943.1 - 0.0015 18.0 14.7 0.042 13.3 3.3 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF745) DUF2130 PF09903.4 AEO63943.1 - 0.0045 15.7 2.8 0.0045 15.7 1.9 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2130) Laminin_II PF06009.7 AEO63943.1 - 0.0046 16.7 6.8 0.0089 15.7 1.8 2.8 2 1 1 3 3 3 1 Laminin Domain II DUF2968 PF11180.3 AEO63943.1 - 0.013 14.8 8.5 0.013 14.8 5.9 3.0 2 2 0 3 3 3 0 Protein of unknown function (DUF2968) IFT57 PF10498.4 AEO63943.1 - 0.016 13.9 8.1 0.05 12.3 1.7 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 MT PF12777.2 AEO63943.1 - 0.055 12.2 5.6 0.23 10.1 1.7 2.2 2 0 0 2 2 2 0 Microtubule-binding stalk of dynein motor Mito_fiss_reg PF05308.6 AEO63943.1 - 0.061 12.6 6.6 0.14 11.4 4.5 1.7 1 1 0 1 1 1 0 Mitochondrial fission regulator Spc7 PF08317.6 AEO63943.1 - 0.071 11.7 13.8 0.048 12.3 3.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein HisKA_3 PF07730.8 AEO63943.1 - 0.1 12.9 13.9 0.44 10.9 2.4 3.6 2 1 1 3 3 3 0 Histidine kinase Sec8_exocyst PF04048.9 AEO63943.1 - 0.15 11.6 4.6 4.9 6.7 1.0 2.7 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain AAA_23 PF13476.1 AEO63943.1 - 0.21 11.8 10.2 0.042 14.1 4.2 1.9 2 1 0 2 2 2 0 AAA domain DUF972 PF06156.8 AEO63943.1 - 0.37 11.1 11.6 10 6.5 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) GAS PF13851.1 AEO63943.1 - 0.65 9.1 17.7 0.53 9.4 4.2 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.1 AEO63943.1 - 0.73 9.2 19.4 2.4 7.5 7.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Nup54 PF13874.1 AEO63943.1 - 0.77 9.4 12.6 0.039 13.5 4.2 2.0 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Med9 PF07544.8 AEO63943.1 - 1.4 8.6 8.4 9.2 6.0 0.0 2.8 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 APG6 PF04111.7 AEO63943.1 - 1.8 7.5 22.0 0.043 12.8 5.4 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 AAA_13 PF13166.1 AEO63943.1 - 2 6.7 9.2 0.1 11.0 1.6 1.8 2 0 0 2 2 2 0 AAA domain Seryl_tRNA_N PF02403.17 AEO63943.1 - 2.1 8.4 16.4 3.4 7.7 4.0 2.9 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Snapin_Pallidin PF14712.1 AEO63943.1 - 2.2 8.6 9.2 9.1 6.6 2.9 3.0 2 1 1 3 3 3 0 Snapin/Pallidin DUF1664 PF07889.7 AEO63943.1 - 2.7 7.8 4.8 6.2 6.6 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2730 PF10805.3 AEO63943.1 - 3 7.6 10.5 0.3 10.8 1.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) KxDL PF10241.4 AEO63943.1 - 3 7.8 10.0 12 5.9 1.2 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein AATF-Che1 PF13339.1 AEO63943.1 - 3.8 7.6 11.8 0.58 10.3 3.2 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF342 PF03961.8 AEO63943.1 - 5 5.4 9.9 0.63 8.4 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF3763 PF12592.3 AEO63943.1 - 5.3 6.7 8.2 4.7 6.9 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3763) DUF883 PF05957.8 AEO63943.1 - 7.4 7.0 14.3 12 6.3 4.7 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) His_Phos_1 PF00300.17 AEO63944.1 - 1.9e-18 67.0 0.0 2.7e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) APH PF01636.18 AEO63945.1 - 1.2e-19 70.9 0.2 1.9e-19 70.3 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO63945.1 - 5.7e-07 29.3 0.0 1.6e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 AEO63945.1 - 1.9e-05 24.1 0.0 0.16 11.3 0.0 2.4 2 0 0 2 2 2 2 RIO1 family EcKinase PF02958.15 AEO63945.1 - 0.00034 19.8 0.0 0.00046 19.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 AEO63945.1 - 0.005 15.5 0.0 0.0082 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) p450 PF00067.17 AEO63946.1 - 1e-43 149.5 0.0 2.2e-43 148.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 EF-1_beta_acid PF10587.4 AEO63946.1 - 0.34 11.1 4.1 1.1 9.4 2.9 1.9 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Cupin_2 PF07883.6 AEO63947.1 - 1.1e-07 31.2 0.0 1.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 AEO63947.1 - 0.00015 21.4 0.1 0.00021 20.9 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 AEO63947.1 - 0.0056 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Polyketide_cyc2 PF10604.4 AEO63948.1 - 0.026 14.6 0.8 0.6 10.2 0.0 2.4 2 1 1 3 3 3 0 Polyketide cyclase / dehydrase and lipid transport Lactamase_B_2 PF12706.2 AEO63949.1 - 1.7e-30 106.0 0.0 3.1e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AEO63949.1 - 3.8e-07 29.9 0.0 7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AEO63949.1 - 0.0013 18.4 0.3 0.0071 16.0 0.2 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily DUF3165 PF11364.3 AEO63951.1 - 0.11 12.6 0.4 0.26 11.4 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3165) Calcyon PF06387.6 AEO63952.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) DUF2417 PF10329.4 AEO63952.1 - 0.093 12.1 3.5 0.13 11.6 0.4 2.2 2 0 0 2 2 2 0 Region of unknown function (DUF2417) RVT_1 PF00078.22 AEO63953.1 - 0.0061 15.9 0.5 0.0061 15.9 0.3 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Bunya_G2 PF03563.8 AEO63953.1 - 0.14 11.0 2.6 0.15 10.9 1.8 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 DUF3523 PF12037.3 AEO63955.1 - 0.0036 16.3 5.0 0.0048 15.9 3.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) Transposase_22 PF02994.9 AEO63955.1 - 0.049 12.1 0.7 0.063 11.7 0.5 1.1 1 0 0 1 1 1 0 L1 transposable element MutS_III PF05192.13 AEO63955.1 - 3 7.5 5.9 8.7 6.0 3.5 2.0 1 1 0 1 1 1 0 MutS domain III 2OG-FeII_Oxy_2 PF13532.1 AEO63956.1 - 1.6e-28 99.8 0.0 2.5e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 AEO63957.1 - 1e-72 244.4 0.0 1.3e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO63957.1 - 1.2e-31 109.7 0.0 1.6e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO63957.1 - 0.0017 17.3 0.0 0.003 16.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO63957.1 - 0.0081 15.9 0.1 0.018 14.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AEO63957.1 - 0.017 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 AEO63957.1 - 0.12 11.3 0.1 0.49 9.4 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cyclin_N PF00134.18 AEO63958.1 - 7.5e-14 51.3 0.0 1.3e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 AEO63958.1 - 2e-10 41.2 0.0 4.8e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Cyclin Pol_alpha_B_N PF08418.5 AEO63958.1 - 0.0064 16.0 2.0 0.012 15.2 1.4 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal MRI PF15325.1 AEO63959.1 - 0.014 16.3 0.4 0.02 15.8 0.3 1.2 1 0 0 1 1 1 0 Modulator of retrovirus infection Glyoxalase_2 PF12681.2 AEO63960.1 - 0.00013 22.5 0.6 0.0066 17.0 0.4 2.2 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AEO63960.1 - 0.0016 18.4 0.0 0.11 12.4 0.0 2.2 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3437 PF11919.3 AEO63961.1 - 1.5e-31 107.9 0.1 6.1e-31 105.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 AEO63961.1 - 0.0018 18.2 2.5 17 5.7 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat Uteroglobin PF01099.12 AEO63961.1 - 0.11 12.2 0.3 36 4.2 0.0 3.8 3 1 0 3 3 3 0 Uteroglobin family Pkinase PF00069.20 AEO63962.1 - 2e-37 128.7 0.0 1.1e-27 96.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO63962.1 - 4.8e-28 97.9 0.0 7.2e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO63962.1 - 0.011 14.7 0.3 0.044 12.8 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family GBP_C PF02841.9 AEO63962.1 - 0.022 13.9 5.0 0.035 13.2 3.5 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain CENP-F_N PF10481.4 AEO63962.1 - 0.68 9.2 5.5 0.13 11.6 1.3 1.7 2 0 0 2 2 2 0 Cenp-F N-terminal domain DUF641 PF04859.7 AEO63962.1 - 3 7.6 8.0 6.6 6.4 5.6 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) IncA PF04156.9 AEO63962.1 - 5.3 6.5 7.0 11 5.5 4.8 1.5 1 0 0 1 1 1 0 IncA protein bZIP_1 PF00170.16 AEO63963.1 - 4.1e-06 26.6 4.4 4.1e-06 26.6 3.1 2.0 2 0 0 2 2 2 1 bZIP transcription factor Pox_A22 PF04848.8 AEO63963.1 - 0.29 11.0 0.1 0.53 10.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A22 protein Complex1_LYR PF05347.10 AEO63964.1 - 1.7e-12 46.9 0.0 3.8e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AEO63964.1 - 9.8e-12 44.9 0.0 2.4e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Complex1_LYR-like UQ_con PF00179.21 AEO63965.1 - 1e-12 47.6 0.2 1.6e-12 47.0 0.1 1.2 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AEO63965.1 - 0.0012 18.7 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain Sec7_N PF12783.2 AEO63966.1 - 7.4e-29 100.3 1.0 1.4e-27 96.2 0.0 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 AEO63966.1 - 1.1e-05 24.8 0.3 0.00062 19.2 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Ipi1_N PF12333.3 AEO63966.1 - 1.1 9.2 5.7 1.2 9.1 0.1 3.9 6 0 0 6 6 6 0 Rix1 complex component involved in 60S ribosome maturation Band_7 PF01145.20 AEO63967.1 - 3.5e-31 108.5 0.6 3.5e-31 108.5 0.4 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 AEO63967.1 - 0.031 13.7 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family Rap1_C PF11626.3 AEO63969.1 - 3.4e-16 58.8 0.0 1.9e-15 56.4 0.0 2.2 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 AEO63969.1 - 2.3e-09 36.8 1.6 4.8e-05 23.0 0.0 2.7 2 0 0 2 2 2 2 Rap1 Myb domain ARID PF01388.16 AEO63969.1 - 0.00016 21.4 0.1 0.00046 19.9 0.0 1.8 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Myb_DNA-bind_6 PF13921.1 AEO63969.1 - 0.024 14.7 0.3 6.2 7.0 0.0 3.5 3 0 0 3 3 3 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO63969.1 - 0.026 14.5 0.0 2.8 8.0 0.0 3.6 3 0 0 3 3 3 0 Myb-like DNA-binding domain Rap1-DNA-bind PF09197.5 AEO63969.1 - 0.035 14.6 0.0 9.9 6.7 0.0 3.2 3 1 0 3 3 3 0 Rap1, DNA-binding Nucleoplasmin PF03066.10 AEO63969.1 - 1.1 8.8 18.7 2.6 7.5 1.5 2.4 2 0 0 2 2 2 0 Nucleoplasmin zf-DHHC PF01529.15 AEO63970.1 - 3.6e-33 114.4 0.2 1.1e-32 112.8 0.1 1.9 1 1 0 1 1 1 1 DHHC palmitoyltransferase MMR_HSR1 PF01926.18 AEO63971.1 - 5e-17 61.9 0.0 8.2e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AEO63971.1 - 3.9e-08 32.9 0.0 1.6e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 AEO63971.1 - 2.5e-05 24.1 0.0 7.8e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Dynamin family DUF258 PF03193.11 AEO63971.1 - 0.00035 19.7 0.0 0.00059 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 AEO63971.1 - 0.00046 19.5 0.0 0.015 14.5 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.22 AEO63971.1 - 0.0089 16.3 0.1 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 AEO63971.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Complex1_LYR_2 PF13233.1 AEO63972.1 - 5.6e-15 55.6 0.1 6.9e-15 55.4 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Aha1_N PF09229.6 AEO63975.1 - 1.6e-38 131.6 0.6 2.8e-38 130.8 0.4 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 AEO63975.1 - 2.2e-18 66.5 1.5 3.3e-18 65.9 0.5 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 AEO63975.1 - 0.0038 17.3 1.8 0.02 15.0 0.3 2.2 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport CN_hydrolase PF00795.17 AEO63976.1 - 4.9e-14 52.0 0.0 8.6e-14 51.3 0.0 1.3 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase ADH_N PF08240.7 AEO63977.1 - 4.8e-23 80.9 1.2 8.5e-23 80.1 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO63977.1 - 6.3e-18 64.5 0.2 1.3e-17 63.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 AEO63977.1 - 0.0003 20.4 1.5 0.00039 20.0 0.2 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 AEO63977.1 - 0.01 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 AEO63977.1 - 0.054 13.1 0.3 0.087 12.4 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AP_endonuc_2 PF01261.19 AEO63977.1 - 0.075 12.3 0.0 0.43 9.8 0.0 1.9 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel ELFV_dehydrog PF00208.16 AEO63977.1 - 0.16 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pkinase PF00069.20 AEO63978.1 - 4.2e-10 39.2 0.0 1.7e-06 27.4 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO63978.1 - 0.0031 16.6 0.0 1.1 8.2 0.0 2.8 3 1 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 AEO63978.1 - 0.093 11.7 0.0 0.65 9.0 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.17 AEO63980.1 - 8.9e-63 212.4 0.0 1.2e-62 212.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Patched PF02460.13 AEO63982.1 - 3.3e-73 246.9 15.8 2.9e-72 243.8 11.0 1.9 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 AEO63982.1 - 1.4e-49 167.4 7.8 1.4e-49 167.4 5.4 2.6 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 AEO63982.1 - 0.0014 17.3 11.3 0.0014 17.3 7.8 2.6 3 0 0 3 3 3 2 MMPL family Smr PF01713.16 AEO63983.1 - 2.7e-11 43.5 1.6 5.9e-11 42.4 0.1 2.3 3 0 0 3 3 3 1 Smr domain His_kinase PF06580.8 AEO63983.1 - 0.1 12.5 0.1 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase Zds_C PF08632.5 AEO63984.1 - 6.4e-31 105.5 0.4 1.2e-30 104.7 0.3 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2433 PF10360.4 AEO63985.1 - 1.2e-55 187.4 0.0 1.9e-55 186.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 AEO63985.1 - 0.0049 16.7 0.0 0.013 15.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AEO63985.1 - 0.0052 16.2 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TFIIA PF03153.8 AEO63985.1 - 1.2 8.9 8.4 2.1 8.1 5.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2360 PF10152.4 AEO63985.1 - 1.2 9.3 22.5 2.2e+02 2.0 15.6 2.5 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) PAT1 PF09770.4 AEO63985.1 - 4.8 5.2 16.9 6.8 4.7 11.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ubie_methyltran PF01209.13 AEO63986.1 - 1.2e-70 237.3 0.0 3.4e-43 147.4 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 AEO63986.1 - 1e-10 41.4 0.0 6.1e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 AEO63986.1 - 4.8e-10 39.7 0.0 5.4e-06 26.7 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.7 AEO63986.1 - 8.7e-09 35.7 0.0 1.6e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO63986.1 - 1.3e-08 34.7 0.0 2.1e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO63986.1 - 1.2e-07 31.9 0.0 3.8e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO63986.1 - 7.9e-06 26.4 0.0 1.7e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO63986.1 - 0.00028 20.8 0.2 0.0011 19.0 0.2 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO63986.1 - 0.016 14.5 0.0 0.56 9.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Bac_chlorC PF02043.12 AEO63986.1 - 0.89 9.3 3.5 9.2 6.1 0.1 2.9 3 0 0 3 3 3 0 Bacteriochlorophyll C binding protein E1_dh PF00676.15 AEO63987.1 - 1.3e-86 290.0 0.0 1.6e-86 289.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 AEO63987.1 - 0.0015 18.0 0.0 0.014 14.9 0.0 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 AEO63987.1 - 0.14 11.0 0.0 0.45 9.3 0.0 1.7 1 1 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase HECT PF00632.20 AEO63988.1 - 2.7e-86 289.6 0.0 8.6e-86 287.9 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 AEO63988.1 - 0.2 11.5 5.7 70 3.4 0.0 6.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 AEO63988.1 - 0.38 10.0 2.5 1 8.6 0.1 2.7 3 0 0 3 3 3 0 CLASP N terminal RRN3 PF05327.6 AEO63988.1 - 1.2 7.1 14.3 0.094 10.8 6.2 1.8 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Sec3_C PF09763.4 AEO63990.1 - 1.7e-250 832.9 0.0 2.4e-250 832.5 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 AEO63990.1 - 1e-30 105.3 0.0 1.9e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 AEO63990.1 - 0.016 15.3 1.9 0.025 14.6 0.0 2.4 3 0 0 3 3 3 0 Sec3 exocyst complex subunit Vps52 PF04129.7 AEO63990.1 - 0.43 9.0 5.5 0.13 10.7 0.2 2.1 2 0 0 2 2 2 0 Vps52 / Sac2 family DUF2018 PF09442.5 AEO63990.1 - 0.66 10.5 3.0 0.42 11.2 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) Fe-ADH PF00465.14 AEO63991.1 - 8.8e-104 347.0 0.0 1.1e-103 346.7 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 AEO63991.1 - 1.6e-14 53.8 0.0 2e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 AEO63991.1 - 1.4e-05 24.5 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein FAD_binding_1 PF00667.15 AEO63992.1 - 2e-61 207.2 0.1 4.7e-61 206.0 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 AEO63992.1 - 2.4e-11 44.1 0.0 1.2e-10 41.9 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.13 AEO63992.1 - 1.6e-07 31.3 0.0 3.8e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 AEO63992.1 - 0.0051 16.7 0.5 0.15 11.9 0.1 2.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain POR_N PF01855.14 AEO63992.1 - 0.063 12.7 0.8 0.21 11.0 0.0 2.1 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg E1-E2_ATPase PF00122.15 AEO63993.1 - 1.5e-51 174.6 0.1 6.7e-51 172.5 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 AEO63993.1 - 7.3e-40 137.6 0.2 1.6e-39 136.5 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 AEO63993.1 - 1.1e-33 115.1 3.5 1.9e-10 40.6 0.1 5.7 6 0 0 6 6 6 4 Heavy-metal-associated domain HAD PF12710.2 AEO63993.1 - 3.7e-16 59.8 0.0 9.2e-16 58.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AEO63993.1 - 3.4e-05 23.5 0.2 0.00053 19.6 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AEO63993.1 - 0.0024 18.1 0.0 0.0057 16.9 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HDOD PF08668.7 AEO63993.1 - 0.037 13.3 0.0 0.18 11.0 0.0 2.1 1 1 0 1 1 1 0 HDOD domain zf-C3HC PF07967.8 AEO63994.1 - 1.2e-39 135.1 0.0 1.4e-37 128.4 0.0 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 AEO63994.1 - 5.4e-20 71.0 1.2 5.7e-19 67.7 0.1 2.9 2 1 0 2 2 2 1 Rsm1-like BIR PF00653.16 AEO63994.1 - 0.00028 21.2 0.1 0.0038 17.6 0.1 2.4 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain RRM_1 PF00076.17 AEO63995.1 - 1e-10 41.0 0.0 1e-09 37.8 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO63995.1 - 2.5e-05 24.1 0.0 8.1e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO63995.1 - 0.00014 21.6 0.0 0.00033 20.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO63995.1 - 0.027 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.3 AEO63995.1 - 0.049 12.9 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated zf-RING_4 PF14570.1 AEO63995.1 - 0.43 10.1 0.6 0.72 9.4 0.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Complex1_30kDa PF00329.14 AEO63996.1 - 1e-35 122.0 0.0 1.5e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Dioxygenase_C PF00775.16 AEO63997.1 - 1.7e-48 164.3 0.0 2.2e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 AEO63997.1 - 6.4e-12 45.2 0.0 1.1e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 AEO63997.1 - 0.021 14.8 0.0 0.087 12.8 0.0 2.0 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Lactonase PF10282.4 AEO63998.1 - 3.8e-15 55.8 0.0 6.1e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller WD40 PF00400.27 AEO63998.1 - 0.047 13.6 0.0 2.4 8.1 0.0 3.4 4 0 0 4 4 4 0 WD domain, G-beta repeat Inositol_P PF00459.20 AEO64000.1 - 1.9e-53 181.4 1.5 3.2e-53 180.7 1.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.18 AEO64001.1 - 1.6e-23 82.9 0.0 1.1e-11 45.0 0.0 2.7 2 1 0 2 2 2 2 Ribosomal protein L6 Tht1 PF04163.7 AEO64002.1 - 1.7e-06 26.7 4.0 4.3e-06 25.4 2.7 1.6 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein Prefoldin PF02996.12 AEO64002.1 - 0.0024 17.5 11.4 0.19 11.3 0.1 3.6 3 0 0 3 3 3 2 Prefoldin subunit NPV_P10 PF05531.7 AEO64002.1 - 0.084 13.1 11.7 0.25 11.6 0.1 3.3 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein LXG PF04740.7 AEO64002.1 - 0.13 12.0 10.9 0.24 11.1 4.1 2.4 1 1 0 2 2 2 0 LXG domain of WXG superfamily DUF948 PF06103.6 AEO64002.1 - 0.15 11.9 6.8 1.7 8.5 0.7 3.2 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.16 AEO64002.1 - 0.28 10.6 12.3 3.8 7.0 7.6 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 AEO64002.1 - 0.79 9.5 9.0 2.5 7.9 0.7 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.1 AEO64002.1 - 0.83 10.0 10.6 0.97 9.7 0.4 3.1 2 1 1 3 3 3 0 Snapin/Pallidin DUF148 PF02520.12 AEO64002.1 - 1.1 9.0 10.5 1.4 8.7 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function DUF148 MbeD_MobD PF04899.7 AEO64002.1 - 1.5 8.8 7.8 10 6.0 0.6 2.9 2 0 0 2 2 2 0 MbeD/MobD like Acyl-CoA_dh_C PF12806.2 AEO64002.1 - 3.9 7.3 8.6 4.9 7.0 0.6 3.4 2 1 1 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like Laminin_II PF06009.7 AEO64002.1 - 4.6 7.0 12.9 5.3 6.7 0.3 2.9 1 1 2 3 3 3 0 Laminin Domain II Ribosomal_60s PF00428.14 AEO64003.1 - 4.4 7.7 13.3 0.49 10.8 5.7 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ion_trans_2 PF07885.11 AEO64004.1 - 8.2e-31 105.5 30.1 2.1e-19 68.9 2.9 3.2 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 AEO64004.1 - 0.068 12.4 17.4 0.22 10.7 0.7 2.7 2 1 0 2 2 2 0 Ion transport protein DUF605 PF04652.11 AEO64004.1 - 1.5 8.1 12.7 2.1 7.6 8.8 1.2 1 0 0 1 1 1 0 Vta1 like K_channel_TID PF07941.6 AEO64004.1 - 2.5 8.3 11.3 2.4 8.4 6.2 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF2217 PF10265.4 AEO64004.1 - 4.7 5.8 6.2 7.3 5.2 4.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) ABC_tran PF00005.22 AEO64005.1 - 4.1e-49 166.3 0.1 9.1e-27 94.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 AEO64005.1 - 1.9e-25 89.6 38.8 1.8e-16 60.1 12.4 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 AEO64005.1 - 3.7e-23 82.9 0.1 5.6e-07 29.8 0.0 4.2 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 AEO64005.1 - 1.7e-09 37.0 2.2 0.00063 19.2 0.2 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.14 AEO64005.1 - 1.3e-07 31.0 4.2 0.079 12.1 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AEO64005.1 - 7e-05 23.2 4.4 0.048 13.9 0.2 2.2 2 0 0 2 2 2 2 AAA domain ABC2_membrane_4 PF12730.2 AEO64005.1 - 0.00031 20.0 16.2 0.00031 20.0 11.2 4.0 2 2 1 3 3 3 1 ABC-2 family transporter protein AAA_16 PF13191.1 AEO64005.1 - 0.0008 19.4 4.2 0.76 9.7 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 AEO64005.1 - 0.0012 18.0 0.4 1.2 8.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 AEO64005.1 - 0.011 15.1 0.8 3.3 7.0 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 AEO64005.1 - 0.018 14.6 0.4 2.9 7.4 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 AEO64005.1 - 0.018 15.1 0.1 3.3 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 AEO64005.1 - 0.029 14.2 0.1 12 5.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.17 AEO64005.1 - 0.037 13.4 0.6 6.2 6.2 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 AEO64005.1 - 0.049 13.5 0.9 14 5.7 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 AEO64005.1 - 0.064 12.6 1.2 4.1 6.7 0.2 2.4 2 0 0 2 2 2 0 AAA-like domain DUF591 PF04569.9 AEO64005.1 - 0.095 12.7 0.4 0.28 11.2 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function MutS_V PF00488.16 AEO64005.1 - 0.12 11.7 0.2 3.8 6.8 0.0 2.5 3 0 0 3 3 3 0 MutS domain V FtsK_SpoIIIE PF01580.13 AEO64005.1 - 0.14 11.6 1.1 0.82 9.1 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF4162 PF13732.1 AEO64005.1 - 0.19 12.2 0.0 25 5.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) Zeta_toxin PF06414.7 AEO64005.1 - 0.27 10.3 0.5 4.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin G-alpha PF00503.15 AEO64005.1 - 0.29 9.7 0.0 1.2 7.7 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit AAA_14 PF13173.1 AEO64005.1 - 0.33 10.8 0.0 13 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 AEO64005.1 - 0.72 9.6 2.2 24 4.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_15 PF13175.1 AEO64005.1 - 0.87 8.5 0.0 13 4.6 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_28 PF13521.1 AEO64005.1 - 1.3 8.9 4.1 35 4.3 0.8 3.1 3 0 0 3 3 3 0 AAA domain AAA_13 PF13166.1 AEO64005.1 - 1.3 7.3 0.1 18 3.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain tRNA-synt_2 PF00152.15 AEO64006.1 - 8.4e-84 281.1 1.3 1.2e-83 280.7 0.9 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AEO64006.1 - 3.7e-12 45.9 0.1 7.2e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AEO64006.1 - 3.2e-09 36.3 0.2 9.5e-05 21.6 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) zf-Di19 PF05605.7 AEO64007.1 - 0.011 15.7 0.2 0.031 14.3 0.2 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Glyco_hydro_75 PF07335.6 AEO64007.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 bZIP_1 PF00170.16 AEO64007.1 - 0.19 11.7 5.6 0.059 13.3 1.3 2.1 2 0 0 2 2 2 0 bZIP transcription factor zf-C2H2 PF00096.21 AEO64007.1 - 0.19 12.1 0.6 0.47 10.9 0.4 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Chromo PF00385.19 AEO64008.1 - 6.9e-13 48.0 1.1 6.9e-13 48.0 0.8 2.5 2 1 1 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 AEO64008.1 - 4.2e-11 42.5 0.0 2e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 Chromo shadow domain DUF1206 PF06724.6 AEO64009.1 - 0.038 13.7 2.5 0.058 13.1 1.8 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) DUF4234 PF14018.1 AEO64009.1 - 0.06 13.0 0.1 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Baculo_11_kDa PF06143.6 AEO64009.1 - 0.08 12.3 0.3 0.083 12.2 0.2 1.1 1 0 0 1 1 1 0 Baculovirus 11 kDa family Internalin_N PF12354.3 AEO64009.1 - 0.089 12.4 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal DUF4307 PF14155.1 AEO64009.1 - 0.094 12.5 0.2 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) DUF3317 PF11779.3 AEO64009.1 - 0.23 10.8 2.5 0.29 10.6 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) PsbN PF02468.10 AEO64009.1 - 0.28 10.8 1.1 0.35 10.4 0.8 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) OppC_N PF12911.2 AEO64009.1 - 0.41 10.0 3.2 0.44 9.9 2.2 1.1 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Tad PF13400.1 AEO64009.1 - 0.46 10.5 3.1 0.55 10.3 2.2 1.1 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Pyridox_oxidase PF01243.15 AEO64011.1 - 1.8e-07 31.0 0.0 0.00066 19.6 0.0 2.7 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.16 AEO64011.1 - 0.0082 16.7 0.0 0.024 15.2 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain CTP_transf_2 PF01467.21 AEO64012.1 - 8.8e-27 94.0 0.0 1.2e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase DctQ PF04290.7 AEO64014.1 - 0.59 9.9 8.8 5.2 6.8 0.1 2.3 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF3753 PF12575.3 AEO64014.1 - 0.95 9.3 7.3 0.32 10.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) His_Phos_1 PF00300.17 AEO64015.1 - 6e-14 52.4 0.2 2e-13 50.7 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) VHS PF00790.14 AEO64019.1 - 1.1e-42 144.9 2.1 1.1e-41 141.7 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 AEO64019.1 - 7.8e-16 57.7 4.7 1.3e-15 56.9 3.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 AEO64019.1 - 0.00017 20.8 15.0 0.0088 15.5 0.5 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-DHHC PF01529.15 AEO64019.1 - 0.003 16.9 1.7 0.0074 15.6 1.2 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ribosomal_S30AE PF02482.14 AEO64019.1 - 0.031 14.7 1.0 0.13 12.7 0.7 2.1 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein GAT PF03127.9 AEO64019.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 GAT domain UCH PF00443.24 AEO64020.1 - 1.2e-42 145.9 0.0 1.8e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO64020.1 - 9.1e-13 48.2 0.0 1.9e-12 47.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 AEO64020.1 - 0.0013 19.0 0.0 0.0041 17.4 0.0 1.9 1 1 0 1 1 1 1 Rhodanese-like domain AMP-binding PF00501.23 AEO64021.1 - 3.3e-78 262.9 0.0 4.4e-78 262.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans_2 PF11951.3 AEO64023.1 - 0.0024 16.5 0.1 0.0038 15.8 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain TPMT PF05724.6 AEO64023.1 - 0.0096 15.3 0.0 0.023 14.1 0.0 1.6 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Peptidase_M24 PF00557.19 AEO64024.1 - 8.8e-44 149.5 0.1 1.2e-43 149.1 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Polysacc_deac_2 PF04748.8 AEO64024.1 - 0.091 11.7 0.2 0.67 8.9 0.0 2.3 3 0 0 3 3 3 0 Divergent polysaccharide deacetylase DUF3295 PF11702.3 AEO64027.1 - 1.6e-154 515.6 28.7 2e-154 515.3 19.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 AEO64027.1 - 5.7e-13 48.1 2.2 1.2e-12 47.1 1.5 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) PBP1_TM PF14812.1 AEO64027.1 - 0.052 13.8 0.8 0.2 11.9 0.5 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mu-like_Com PF10122.4 AEO64028.1 - 5.7e-05 22.0 0.2 0.00014 20.8 0.2 1.7 1 0 0 1 1 1 1 Mu-like prophage protein Com RWD PF05773.17 AEO64028.1 - 0.00063 19.6 0.4 0.02 14.7 0.0 2.4 2 0 0 2 2 2 1 RWD domain DUF3275 PF11679.3 AEO64028.1 - 0.2 11.2 2.1 0.63 9.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) VHS PF00790.14 AEO64029.1 - 1.5e-26 92.7 0.0 2.8e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 AEO64029.1 - 5.2e-11 42.4 3.6 5.2e-11 42.4 2.5 1.7 2 0 0 2 2 2 1 GAT domain DUF2562 PF10814.3 AEO64029.1 - 0.36 10.7 6.2 0.22 11.4 1.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2562) zf-C2H2_2 PF12756.2 AEO64030.1 - 1.3e-36 124.7 3.2 1.3e-28 99.0 0.1 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 AEO64030.1 - 7.2e-10 38.7 10.4 3.2e-06 27.1 1.9 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO64030.1 - 1.2e-08 34.8 6.6 1.4e-07 31.4 0.8 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 AEO64030.1 - 6.1e-05 23.1 14.6 0.044 14.1 0.3 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-DBF PF07535.7 AEO64030.1 - 0.0031 17.1 4.4 0.013 15.1 0.1 3.2 3 0 0 3 3 3 1 DBF zinc finger AKAP95 PF04988.7 AEO64030.1 - 0.024 14.4 3.1 2.8 7.6 0.0 2.8 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 AEO64030.1 - 0.04 14.2 14.1 0.31 11.4 0.6 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger SnoaL_2 PF12680.2 AEO64030.1 - 0.054 13.9 0.4 0.14 12.5 0.3 1.7 1 0 0 1 1 1 0 SnoaL-like domain zf-C2H2_6 PF13912.1 AEO64030.1 - 0.12 12.2 7.4 0.51 10.3 0.0 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger HECT PF00632.20 AEO64031.1 - 2.1e-68 230.8 0.0 3e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Cpn60_TCP1 PF00118.19 AEO64032.1 - 6.5e-147 490.0 2.7 7.4e-147 489.8 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 AEO64032.1 - 0.17 11.7 1.5 42 4.0 0.0 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain GTP_EFTU PF00009.22 AEO64033.1 - 6.1e-48 162.7 0.0 8.2e-48 162.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AEO64033.1 - 3.2e-08 33.6 0.2 3e-07 30.5 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 AEO64033.1 - 1.2e-07 31.6 0.0 2.7e-06 27.2 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 AEO64033.1 - 1.8e-06 27.9 0.0 5.1e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 AEO64033.1 - 8e-05 23.1 0.1 0.0019 18.6 0.1 2.5 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 AEO64033.1 - 0.00019 21.0 0.0 0.00044 19.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SRPRB PF09439.5 AEO64033.1 - 0.0089 15.2 0.1 0.66 9.1 0.0 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AEO64033.1 - 0.034 13.5 0.2 0.39 10.1 0.0 2.3 2 0 0 2 2 2 0 Ras family Septin PF00735.13 AEO64033.1 - 0.042 12.8 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Septin FeoB_N PF02421.13 AEO64033.1 - 0.073 12.3 0.0 1.8 7.8 0.0 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B HSP70 PF00012.15 AEO64034.1 - 1.5e-271 901.6 14.2 1.7e-271 901.4 9.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AEO64034.1 - 1.4e-18 66.5 2.9 2.8e-17 62.3 0.7 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 AEO64034.1 - 0.0028 16.7 5.2 0.0087 15.1 0.2 3.1 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase DDR PF08841.5 AEO64034.1 - 0.0068 15.2 2.2 0.052 12.3 0.1 2.5 3 0 0 3 3 3 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.1 AEO64034.1 - 0.32 10.8 8.1 4.4 7.1 0.1 4.0 2 1 0 2 2 2 0 Cell division protein FtsA SpoIIAA-like PF11964.3 AEO64034.1 - 1.2 9.4 4.2 18 5.6 0.1 3.3 3 0 0 3 3 3 0 SpoIIAA-like Tektin PF03148.9 AEO64035.1 - 0.15 10.5 0.5 0.21 10.1 0.4 1.1 1 0 0 1 1 1 0 Tektin family SLD3 PF08639.5 AEO64035.1 - 1.5 7.3 6.1 1.8 7.1 4.2 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 DUF500 PF04366.7 AEO64039.1 - 8.3e-45 151.2 0.1 1.6e-44 150.3 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 AEO64039.1 - 3.5e-15 55.1 0.2 1.6e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 AEO64039.1 - 8.2e-14 50.9 0.5 1.4e-13 50.2 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 AEO64039.1 - 4.8e-12 45.1 0.0 1.1e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Synaptobrevin PF00957.16 AEO64040.1 - 0.028 13.9 0.5 0.26 10.9 0.2 2.0 1 1 1 2 2 2 0 Synaptobrevin ArfGap PF01412.13 AEO64041.1 - 1.1e-40 138.0 0.6 1.7e-40 137.4 0.4 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelR PF01641.13 AEO64042.1 - 5.3e-51 171.5 0.0 6.7e-51 171.1 0.0 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 AEO64042.1 - 0.0041 16.8 0.9 0.38 10.6 0.1 2.4 2 0 0 2 2 2 1 Double zinc ribbon zf-Mss51 PF13824.1 AEO64042.1 - 0.07 12.9 2.6 1 9.2 0.3 3.0 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 GFA PF04828.9 AEO64042.1 - 0.083 12.8 0.3 2.7 8.0 0.0 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2296 PF10058.4 AEO64042.1 - 0.1 12.3 0.4 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Ribosomal_L37e PF01907.14 AEO64042.1 - 0.14 11.9 3.4 0.99 9.2 0.6 2.5 2 0 0 2 2 2 0 Ribosomal protein L37e zf-ribbon_3 PF13248.1 AEO64042.1 - 0.14 11.3 1.9 9 5.6 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AEO64042.1 - 0.21 11.1 1.7 4.6 6.8 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 AEO64042.1 - 0.25 11.6 3.6 5.3 7.3 0.4 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain TF_Zn_Ribbon PF08271.7 AEO64042.1 - 0.52 9.6 5.0 3 7.2 0.2 2.7 3 0 0 3 3 3 0 TFIIB zinc-binding ARID PF01388.16 AEO64044.1 - 1.5e-19 69.5 0.0 3.1e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain V-ATPase_H_N PF03224.9 AEO64044.1 - 0.16 11.0 0.1 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H adh_short PF00106.20 AEO64045.1 - 8.8e-31 107.0 0.9 1.5e-30 106.2 0.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO64045.1 - 2e-28 99.8 0.2 2.8e-28 99.3 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO64045.1 - 1.7e-11 44.0 0.2 2.9e-11 43.3 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO64045.1 - 1.8e-05 24.3 0.2 6e-05 22.5 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.17 AEO64045.1 - 0.0082 15.8 0.2 0.024 14.3 0.1 1.8 1 0 0 1 1 1 1 PA domain Polysacc_synt_2 PF02719.10 AEO64045.1 - 0.01 14.7 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 AEO64045.1 - 0.019 13.6 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pkinase PF00069.20 AEO64046.1 - 1.3e-71 240.8 0.0 1.8e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO64046.1 - 3.3e-45 154.1 0.0 5.3e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 AEO64046.1 - 2.3e-16 59.9 0.0 7.3e-16 58.3 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 AEO64046.1 - 2.8e-07 29.7 0.5 4.8e-07 29.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AEO64046.1 - 0.088 12.5 0.0 0.088 12.5 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family KH_1 PF00013.24 AEO64047.1 - 4.2e-92 301.7 33.2 6.9e-13 48.0 0.1 13.5 14 1 0 14 14 14 10 KH domain KH_3 PF13014.1 AEO64047.1 - 8.3e-69 226.3 23.8 2.4e-10 39.8 0.0 12.9 13 0 0 13 13 13 9 KH domain SLS PF14611.1 AEO64047.1 - 7.2e-16 58.2 6.4 0.0054 16.1 0.0 7.3 5 3 3 8 8 8 5 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 AEO64047.1 - 6.2e-12 44.9 17.2 0.043 13.3 0.0 7.9 7 1 1 8 8 8 4 KH domain FtsQ PF03799.10 AEO64047.1 - 0.0028 17.8 0.6 31 4.7 0.0 5.5 5 1 1 6 6 6 0 Cell division protein FtsQ KH_4 PF13083.1 AEO64047.1 - 0.32 10.6 7.4 0.63 9.7 0.1 4.9 6 0 0 6 6 6 0 KH domain APH PF01636.18 AEO64048.1 - 0.00077 19.2 0.0 0.0013 18.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 AEO64048.1 - 0.003 16.5 0.0 0.004 16.1 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase Med20 PF08612.6 AEO64048.1 - 0.021 13.9 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Ribosomal_60s PF00428.14 AEO64049.1 - 0.0053 17.1 2.5 0.0053 17.1 1.7 2.4 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF3899 PF13038.1 AEO64049.1 - 0.095 12.8 0.6 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Atrophin-1 PF03154.10 AEO64049.1 - 1.1 7.2 9.2 0.67 8.0 1.9 2.1 2 0 0 2 2 2 0 Atrophin-1 family Rpp20 PF12328.3 AEO64049.1 - 4.3 6.9 8.7 0.27 10.8 1.7 2.0 3 0 0 3 3 3 0 Rpp20 subunit of nuclear RNase MRP and P Atx10homo_assoc PF09759.4 AEO64051.1 - 7.4e-11 41.6 0.0 2.4e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain PNP_UDP_1 PF01048.15 AEO64052.1 - 4e-38 130.6 1.5 4.8e-38 130.4 1.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Med13_C PF06333.7 AEO64053.1 - 1.9e-115 385.7 0.0 2.8e-115 385.2 0.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 AEO64053.1 - 6.4e-52 176.5 0.0 6.3e-29 100.8 0.0 2.7 2 1 1 3 3 3 2 Mediator complex subunit 13 N-terminal DUF521 PF04412.8 AEO64053.1 - 0.57 8.6 0.0 0.89 8.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) NUC153 PF08159.7 AEO64054.1 - 2.5e-12 46.1 2.1 4.7e-12 45.2 1.4 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 AEO64054.1 - 3.5e-05 23.5 0.0 0.012 15.4 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat Reo_sigmaC PF04582.7 AEO64055.1 - 0.032 13.4 36.0 0.0083 15.3 2.7 4.9 1 1 4 5 5 5 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 AEO64055.1 - 0.23 9.9 72.3 0.012 14.0 14.1 3.6 1 1 3 4 4 4 0 AAA domain Baculo_PEP_C PF04513.7 AEO64055.1 - 1.4 8.7 47.4 0.37 10.6 1.8 6.6 2 2 4 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 AEO64055.1 - 2.3 8.3 65.9 0.29 11.2 6.7 6.5 2 1 5 7 7 7 0 Fibrinogen alpha/beta chain family Ribosomal_L33 PF00471.15 AEO64056.1 - 4.6e-06 26.7 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Aminotran_1_2 PF00155.16 AEO64057.1 - 4.2e-38 131.2 0.0 5.5e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RPN7 PF10602.4 AEO64058.1 - 2.2e-57 193.2 0.4 4.4e-57 192.2 0.3 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 AEO64058.1 - 4.6e-13 49.3 0.0 1e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.1 AEO64058.1 - 0.097 13.3 1.0 2.2 9.1 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Pox_MCEL PF03291.11 AEO64059.1 - 1.7e-65 221.1 0.0 2.1e-46 158.3 0.0 2.2 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_18 PF12847.2 AEO64059.1 - 1.6e-09 38.3 0.1 2.2e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO64059.1 - 1.7e-09 38.0 0.2 0.0015 18.9 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 AEO64059.1 - 1.4e-06 27.9 0.0 0.00011 21.8 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO64059.1 - 1.6e-06 28.4 0.4 0.069 13.6 0.0 2.9 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 AEO64059.1 - 5.1e-06 26.7 0.0 2e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 AEO64059.1 - 5.6e-06 25.5 0.0 1.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.1 AEO64059.1 - 1e-05 25.3 0.0 3.5e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Raftlin PF15250.1 AEO64059.1 - 0.00019 20.1 0.3 0.00019 20.1 0.2 1.9 2 0 0 2 2 2 1 Raftlin Dicty_REP PF05086.7 AEO64059.1 - 0.005 14.6 2.0 0.0077 14.0 1.4 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Methyltransf_9 PF08003.6 AEO64059.1 - 0.042 12.5 0.0 0.071 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Rubella_E2 PF05749.6 AEO64059.1 - 0.064 12.4 0.4 0.11 11.7 0.3 1.3 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 DUF1314 PF07013.6 AEO64059.1 - 0.084 12.2 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) MGC-24 PF05283.6 AEO64059.1 - 0.1 12.3 6.2 0.18 11.6 4.3 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Mucin PF01456.12 AEO64059.1 - 0.1 12.3 16.6 0.2 11.4 11.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 AEO64059.1 - 1.5 6.6 13.8 2.3 6.0 9.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 AEO64059.1 - 8.7 6.1 9.9 17 5.1 6.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Miro PF08477.8 AEO64060.1 - 5.3e-35 120.4 0.0 1.3e-19 70.8 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 AEO64060.1 - 1.3e-33 114.5 0.0 2.8e-33 113.5 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 AEO64060.1 - 6e-33 111.9 0.5 1.1e-32 111.0 0.1 1.7 2 0 0 2 2 1 1 EF hand associated Ras PF00071.17 AEO64060.1 - 8.3e-23 80.5 0.0 6.2e-15 54.9 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 AEO64060.1 - 2.7e-09 36.9 0.0 2.5e-05 24.1 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 AEO64060.1 - 1.5e-08 34.6 0.3 0.0005 20.1 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 AEO64060.1 - 2.4e-07 29.5 4.1 0.0065 15.7 0.1 2.6 2 0 0 2 2 2 2 EF hand AAA_22 PF13401.1 AEO64060.1 - 1.6e-06 28.3 0.0 0.074 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain EF-hand_6 PF13405.1 AEO64060.1 - 4.1e-06 26.2 3.0 0.028 14.2 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain AAA_16 PF13191.1 AEO64060.1 - 4.2e-06 26.8 0.2 0.046 13.6 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.18 AEO64060.1 - 4.3e-06 26.6 0.1 0.14 11.9 0.1 3.2 2 1 1 3 3 3 2 Dynamin family AAA_29 PF13555.1 AEO64060.1 - 7.7e-06 25.3 0.0 0.0081 15.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF-hand_5 PF13202.1 AEO64060.1 - 5e-05 22.4 4.4 0.15 11.4 1.3 2.7 2 0 0 2 2 2 2 EF hand ABC_tran PF00005.22 AEO64060.1 - 0.00013 22.2 0.0 0.29 11.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 AEO64060.1 - 0.0002 20.6 0.0 0.62 9.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 AEO64060.1 - 0.00024 20.5 0.0 2.8 7.3 0.0 3.2 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 AEO64060.1 - 0.00076 19.1 0.0 0.057 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 AEO64060.1 - 0.00092 18.9 0.0 0.25 11.0 0.1 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 AEO64060.1 - 0.0021 17.4 0.0 1.8 7.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 AEO64060.1 - 0.0035 17.0 0.0 2.3 7.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 AEO64060.1 - 0.0044 17.1 0.0 0.84 9.8 0.0 2.5 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.8 AEO64060.1 - 0.0044 15.9 0.0 1.5 7.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.1 AEO64060.1 - 0.0049 17.2 0.0 0.58 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain EF-hand_10 PF14788.1 AEO64060.1 - 0.0068 16.0 1.6 0.068 12.8 0.2 2.4 2 0 0 2 2 2 1 EF hand AAA_33 PF13671.1 AEO64060.1 - 0.01 15.6 0.0 6.1 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.1 AEO64060.1 - 0.011 15.3 3.7 1.6 8.4 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair AAA_28 PF13521.1 AEO64060.1 - 0.018 14.9 0.0 4 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 AEO64060.1 - 0.023 13.5 0.2 1.2 7.8 0.0 2.7 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) Zeta_toxin PF06414.7 AEO64060.1 - 0.025 13.6 0.0 0.77 8.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin SMC_N PF02463.14 AEO64060.1 - 0.028 13.6 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.14 AEO64060.1 - 0.029 13.7 0.2 4.1 6.8 0.0 3.5 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 AEO64060.1 - 0.04 12.9 0.0 0.5 9.3 0.0 2.1 2 0 0 2 2 2 0 Septin Arch_ATPase PF01637.13 AEO64060.1 - 0.046 13.4 0.0 3.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase SPARC_Ca_bdg PF10591.4 AEO64060.1 - 0.094 12.7 0.1 5 7.2 0.0 2.8 3 0 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region AAA_17 PF13207.1 AEO64060.1 - 0.13 13.0 0.0 25 5.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.11 AEO64060.1 - 0.17 10.9 1.2 1.4 7.9 0.1 2.6 3 0 0 3 3 3 0 AIG1 family ATP_bind_1 PF03029.12 AEO64060.1 - 0.18 11.3 0.1 35 3.8 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.1 AEO64060.1 - 0.21 11.1 0.0 4 6.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 AEO64061.1 - 1e-21 75.9 15.8 5.8e-07 29.1 0.4 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat IKI3 PF04762.7 AEO64061.1 - 0.00055 17.9 0.0 0.00073 17.5 0.0 1.1 1 0 0 1 1 1 1 IKI3 family eIF2A PF08662.6 AEO64061.1 - 0.004 16.8 0.0 0.016 14.8 0.0 1.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 AEO64061.1 - 0.07 12.8 0.0 20 4.9 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Arrestin_C PF02752.17 AEO64062.1 - 6.7e-18 65.1 0.0 1.9e-17 63.6 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 AEO64062.1 - 1.3e-14 54.3 0.0 6.2e-14 52.0 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 AEO64062.1 - 0.0011 18.4 0.0 0.0034 16.9 0.0 1.8 2 0 0 2 2 2 1 Arrestin_N terminal like DUF2419 PF10343.4 AEO64063.1 - 0.045 13.0 1.5 0.096 11.9 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2419) Apolipoprotein PF01442.13 AEO64063.1 - 0.054 13.0 1.6 0.11 12.0 1.1 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Orthopox_A5L PF06193.6 AEO64063.1 - 0.14 12.0 1.2 0.16 11.8 0.1 1.7 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like eRF1_3 PF03465.10 AEO64063.1 - 0.21 11.8 1.1 0.71 10.1 0.0 2.2 2 1 1 3 3 3 0 eRF1 domain 3 CK2S PF15011.1 AEO64063.1 - 0.26 11.0 1.6 0.74 9.5 0.0 2.3 2 1 1 3 3 3 0 Casein Kinase 2 substrate Clr5 PF14420.1 AEO64064.1 - 3.1e-18 65.3 2.1 3.9e-18 65.0 1.5 1.1 1 0 0 1 1 1 1 Clr5 domain zf-Nse PF11789.3 AEO64065.1 - 1.2e-20 72.8 0.5 1.9e-20 72.0 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 AEO64065.1 - 0.00054 19.4 0.4 0.0011 18.4 0.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_2 PF13639.1 AEO64065.1 - 0.00086 19.0 0.3 0.0014 18.4 0.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 AEO64065.1 - 0.0026 17.4 1.7 0.0031 17.1 0.2 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 AEO64065.1 - 0.0088 15.8 0.1 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 AEO64065.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein AAA_13 PF13166.1 AEO64065.1 - 0.074 11.4 2.6 0.11 10.9 1.8 1.1 1 0 0 1 1 1 0 AAA domain zf-rbx1 PF12678.2 AEO64065.1 - 0.077 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 AEO64065.1 - 0.086 12.5 0.6 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 AEO64065.1 - 0.099 12.1 0.2 0.49 9.9 0.1 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.1 AEO64065.1 - 0.14 12.0 0.7 0.22 11.4 0.5 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 AEO64065.1 - 0.18 11.8 0.9 0.31 11.0 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DTHCT PF08070.6 AEO64065.1 - 0.38 11.4 0.1 0.38 11.4 0.1 3.2 4 0 0 4 4 4 0 DTHCT (NUC029) region Glyco_hydro_7 PF00840.15 AEO64066.1 - 1.1e-208 692.9 22.7 1.2e-208 692.8 15.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 His_Phos_2 PF00328.17 AEO64067.1 - 5e-12 45.8 0.0 8.8e-10 38.4 0.0 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Cupin_2 PF07883.6 AEO64068.1 - 6.6e-05 22.3 0.0 9.6e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_2 PF07883.6 AEO64069.1 - 5e-06 25.9 0.0 7.7e-06 25.3 0.0 1.4 1 1 1 2 2 2 1 Cupin domain AraC_binding PF02311.14 AEO64069.1 - 0.001 18.7 0.0 0.0011 18.6 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 AEO64069.1 - 0.023 14.1 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Cupin Cupin_6 PF12852.2 AEO64069.1 - 0.045 13.3 0.0 0.045 13.3 0.0 1.0 1 0 0 1 1 1 0 Cupin ARD PF03079.9 AEO64069.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 ARD/ARD' family Fapy_DNA_glyco PF01149.19 AEO64070.1 - 5.1e-25 88.0 0.0 8.1e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 AEO64070.1 - 6.3e-20 70.7 0.0 1.1e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 AEO64070.1 - 0.0034 15.9 0.0 0.0086 14.6 0.0 1.6 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) CAP_N PF01213.14 AEO64071.1 - 0.27 10.4 2.9 0.48 9.6 2.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Methyltransf_23 PF13489.1 AEO64072.1 - 3.9e-21 75.4 0.0 5.5e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO64072.1 - 5e-15 55.7 0.0 1.1e-13 51.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO64072.1 - 9.1e-15 55.2 0.0 1.3e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO64072.1 - 4.3e-12 46.3 0.0 1.8e-11 44.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO64072.1 - 3.2e-11 43.0 0.0 2.5e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 AEO64072.1 - 1.1e-08 35.0 0.0 2.8e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO64072.1 - 5.7e-05 23.4 0.0 9.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AEO64072.1 - 0.00045 19.3 0.0 0.074 12.1 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase PrmA PF06325.8 AEO64072.1 - 0.00076 18.6 0.0 0.0092 15.1 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 AEO64072.1 - 0.001 18.4 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DUF1958 PF09211.5 AEO64072.1 - 0.15 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) DHBP_synthase PF00926.14 AEO64073.1 - 6.7e-72 240.7 0.0 3e-71 238.6 0.0 1.8 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Utp14 PF04615.8 AEO64074.1 - 5.6e-184 613.3 51.1 5.6e-184 613.3 35.4 2.0 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.4 AEO64075.1 - 1e-17 63.7 0.3 1.4e-17 63.3 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Abhydrolase_3 PF07859.8 AEO64076.1 - 2.5e-39 135.0 0.2 6.6e-30 104.2 0.2 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 AEO64076.1 - 5.9e-14 51.4 0.0 3e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 AEO64076.1 - 0.0034 17.1 0.0 0.0074 16.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 AEO64076.1 - 0.0063 15.2 0.4 0.15 10.7 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family zf-RING_2 PF13639.1 AEO64077.1 - 1.8e-10 40.4 3.2 2.8e-10 39.8 2.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AEO64077.1 - 5.1e-06 26.5 0.7 1.3e-05 25.2 0.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 AEO64077.1 - 6.3e-05 22.5 0.4 9.3e-05 22.0 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO64077.1 - 0.00014 21.8 2.9 0.00021 21.2 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AEO64077.1 - 0.00029 20.6 0.4 0.00049 19.8 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 AEO64077.1 - 0.0014 18.2 0.8 0.0024 17.5 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 AEO64077.1 - 0.018 14.4 1.5 0.67 9.4 0.3 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_3 PF14369.1 AEO64077.1 - 0.021 14.7 1.1 0.19 11.7 0.1 2.4 2 0 0 2 2 2 0 zinc-finger zf-RING_5 PF14634.1 AEO64077.1 - 0.037 13.7 0.6 0.074 12.7 0.4 1.5 1 1 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.1 AEO64077.1 - 0.16 11.5 1.1 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 AEO64077.1 - 0.19 11.3 3.7 0.9 9.1 2.8 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 AEO64077.1 - 0.21 11.5 1.1 3 7.8 0.7 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Pkinase PF00069.20 AEO64079.1 - 2.9e-60 203.6 0.0 3.7e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO64079.1 - 3e-31 108.4 0.0 4e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO64079.1 - 0.00013 21.0 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO64079.1 - 0.014 15.1 0.2 0.014 15.1 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 AEO64079.1 - 0.032 13.3 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAT1 PF09770.4 AEO64079.1 - 3.4 5.8 11.3 4.5 5.3 7.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4078 PF13300.1 AEO64080.1 - 2.8e-29 101.0 18.8 2.8e-29 101.0 13.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4078) TBD PF12845.2 AEO64080.1 - 0.0046 16.4 1.2 0.0071 15.8 0.1 1.9 2 0 0 2 2 2 1 TBD domain Borrelia_P83 PF05262.6 AEO64080.1 - 9.6 4.3 21.3 0.38 8.9 7.9 2.0 2 0 0 2 2 2 0 Borrelia P83/100 protein Homoserine_dh PF00742.14 AEO64081.1 - 7.7e-52 175.5 0.0 9.9e-52 175.1 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 AEO64081.1 - 7.6e-18 65.0 0.0 1.3e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Methyltransf_4 PF02390.12 AEO64082.1 - 3e-53 179.7 0.0 3.8e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 AEO64082.1 - 1.3e-05 25.1 0.4 3.3e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO64082.1 - 0.0002 21.9 0.0 0.00038 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 AEO64082.1 - 0.0099 14.8 0.0 0.022 13.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_31 PF13847.1 AEO64082.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 AEO64082.1 - 0.035 14.5 0.0 0.086 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 AEO64082.1 - 0.044 13.1 0.0 0.083 12.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 AEO64082.1 - 0.054 13.9 0.0 0.65 10.5 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Ndc80_HEC PF03801.8 AEO64083.1 - 4.6e-61 204.9 0.2 1.2e-60 203.5 0.1 1.7 1 0 0 1 1 1 1 HEC/Ndc80p family WASH_WAHD PF11945.3 AEO64083.1 - 0.0054 16.0 4.4 0.0054 16.0 3.0 1.8 2 0 0 2 2 2 1 WAHD domain of WASH complex DUF1664 PF07889.7 AEO64083.1 - 0.0086 15.8 0.8 0.0086 15.8 0.5 4.3 2 2 2 4 4 4 1 Protein of unknown function (DUF1664) 2OG-Fe_Oxy_2 PF10014.4 AEO64083.1 - 0.0094 15.3 0.1 0.28 10.5 0.0 2.5 2 0 0 2 2 2 1 2OG-Fe dioxygenase Tropomyosin_1 PF12718.2 AEO64083.1 - 0.28 11.0 61.8 0.31 10.8 14.9 4.4 2 2 2 4 4 4 0 Tropomyosin like OmpH PF03938.9 AEO64083.1 - 0.57 10.1 40.1 1.5 8.7 7.9 3.4 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Spc7 PF08317.6 AEO64083.1 - 0.99 7.9 37.6 0.2 10.3 7.2 2.8 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF3584 PF12128.3 AEO64083.1 - 1.2 6.4 41.4 1.4 6.1 12.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.5 AEO64083.1 - 1.9 8.6 26.9 3.3 7.8 0.0 4.9 3 2 2 5 5 5 0 Fibrinogen alpha/beta chain family SecIII_SopE_N PF05364.9 AEO64083.1 - 1.9 8.3 4.8 36 4.2 0.0 4.1 4 0 0 4 4 4 0 Salmonella type III secretion SopE effector N-terminus LRS4 PF10422.4 AEO64083.1 - 2 7.7 21.2 2.1 7.6 5.2 2.3 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 Filament PF00038.16 AEO64083.1 - 4.9 6.5 51.6 2.4 7.5 16.5 2.6 2 1 0 2 2 2 0 Intermediate filament protein DUF4510 PF14971.1 AEO64083.1 - 7.6 6.6 15.5 0.37 10.9 2.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) Atg14 PF10186.4 AEO64083.1 - 7.9 5.3 33.7 1.3 7.9 9.4 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 AEO64083.1 - 10 3.8 35.3 5 4.8 9.3 2.4 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Pex14_N PF04695.8 AEO64084.1 - 1.2e-39 135.4 6.8 3.9e-39 133.8 0.0 2.5 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C4H2 PF10146.4 AEO64084.1 - 7.4e-07 29.4 3.5 7.4e-07 29.4 2.4 2.1 2 0 0 2 2 2 1 Zinc finger-containing protein ERM PF00769.14 AEO64084.1 - 0.00027 20.5 10.1 0.00047 19.7 7.0 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF3584 PF12128.3 AEO64084.1 - 0.00048 17.6 9.4 0.00059 17.3 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF848 PF05852.6 AEO64084.1 - 0.0036 17.1 8.8 0.0073 16.1 6.1 1.5 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) CR6_interact PF10147.4 AEO64084.1 - 0.0075 15.6 0.7 0.014 14.7 0.5 1.5 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF1978 PF09321.5 AEO64084.1 - 0.014 14.8 6.9 0.026 13.9 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) IncA PF04156.9 AEO64084.1 - 0.098 12.2 12.3 0.2 11.2 8.5 1.5 1 0 0 1 1 1 0 IncA protein Baculo_PEP_C PF04513.7 AEO64084.1 - 0.21 11.4 6.4 3.9 7.2 0.4 2.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 AEO64084.1 - 0.4 9.0 10.4 0.084 11.3 3.0 1.8 1 1 1 2 2 2 0 AAA domain HLH PF00010.21 AEO64084.1 - 1.2 8.8 7.2 26 4.6 2.1 3.1 1 1 1 2 2 2 0 Helix-loop-helix DNA-binding domain TBPIP PF07106.8 AEO64084.1 - 1.3 8.5 8.5 0.47 9.9 1.8 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3708 PF12501.3 AEO64084.1 - 1.3 8.7 5.1 7.5 6.3 1.5 2.7 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter Prominin PF05478.6 AEO64084.1 - 1.5 6.2 3.1 2.1 5.7 2.1 1.1 1 0 0 1 1 1 0 Prominin Sipho_Gp157 PF05565.6 AEO64084.1 - 2.1 7.9 9.7 9.2 5.8 0.5 2.3 1 1 1 2 2 2 0 Siphovirus Gp157 DUF724 PF05266.9 AEO64084.1 - 2.3 7.8 6.4 3.6 7.1 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Syntaxin PF00804.20 AEO64084.1 - 2.7 8.2 10.0 25 5.1 6.9 2.3 1 1 0 1 1 1 0 Syntaxin FUSC PF04632.7 AEO64084.1 - 6.2 5.1 7.1 8.6 4.6 4.6 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family Atg14 PF10186.4 AEO64084.1 - 6.3 5.6 10.0 9.9 4.9 6.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2968 PF11180.3 AEO64084.1 - 6.4 6.1 12.2 24 4.2 7.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) TPR_MLP1_2 PF07926.7 AEO64084.1 - 6.6 6.4 11.9 0.64 9.7 2.6 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FlgN PF05130.7 AEO64084.1 - 8.1 6.6 11.6 7.4 6.8 6.9 1.7 2 0 0 2 2 2 0 FlgN protein Abhydrolase_3 PF07859.8 AEO64085.1 - 1.6e-21 76.8 0.1 3.3e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold HeLo PF14479.1 AEO64087.1 - 8.5e-58 195.5 0.0 1.4e-57 194.8 0.0 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.20 AEO64087.1 - 0.12 11.4 0.0 0.31 10.1 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain Patatin PF01734.17 AEO64088.1 - 2.7e-30 105.8 0.0 4.4e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Na_Ca_ex PF01699.19 AEO64089.1 - 5.4e-47 158.9 32.5 4.5e-26 91.1 5.7 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Neurensin PF14927.1 AEO64089.1 - 0.42 9.9 0.0 0.42 9.9 0.0 2.4 2 1 0 2 2 2 0 Neurensin DUF1345 PF07077.6 AEO64089.1 - 1.1 8.7 0.0 1.1 8.7 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1345) zf-C2H2 PF00096.21 AEO64090.1 - 2.7e-22 77.6 25.1 2.2e-06 27.6 0.1 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO64090.1 - 2.3e-19 68.6 27.1 3.6e-07 30.1 0.4 4.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO64090.1 - 2e-15 55.9 24.0 0.00033 20.7 2.7 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 AEO64090.1 - 0.00015 21.8 7.9 2.9 8.2 0.0 4.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AEO64090.1 - 0.0011 19.0 8.3 6.7 6.9 0.0 4.7 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AEO64090.1 - 0.0021 17.9 14.1 0.57 10.1 0.4 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 AEO64090.1 - 0.075 12.9 7.8 8.7 6.3 0.3 3.5 3 0 0 3 3 3 0 Zinc ribbon domain XPA_N PF01286.13 AEO64090.1 - 0.15 11.7 0.2 0.15 11.7 0.2 3.4 4 0 0 4 4 4 0 XPA protein N-terminal DUF2256 PF10013.4 AEO64090.1 - 1.8 8.3 4.6 14 5.5 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_ribbon_recom PF13408.1 AEO64090.1 - 5.4 7.3 10.6 4.5 7.6 0.5 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain PAT1 PF09770.4 AEO64090.1 - 9 4.3 49.6 0.039 12.2 22.5 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF3306 PF11748.3 AEO64090.1 - 9.2 6.9 16.1 18 6.0 6.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) DSBA PF01323.15 AEO64091.1 - 3.5e-17 62.5 0.0 3.9e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Dermcidin PF15291.1 AEO64092.1 - 0.072 13.2 1.7 0.09 12.9 0.3 1.8 2 0 0 2 2 2 0 Dermcidin, antibiotic peptide Cyt-b5 PF00173.23 AEO64093.1 - 6.5e-26 89.9 0.2 8.6e-26 89.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4366 PF14283.1 AEO64093.1 - 0.059 12.7 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) F-actin_cap_A PF01267.12 AEO64094.1 - 8.3e-89 297.2 0.0 9.3e-89 297.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Transket_pyr PF02779.19 AEO64095.1 - 3.7e-43 147.0 0.0 6.2e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 AEO64095.1 - 2.1e-31 108.4 0.1 4.8e-31 107.2 0.0 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain Cellulase PF00150.13 AEO64096.1 - 7e-12 45.1 1.1 8.3e-12 44.8 0.0 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.11 AEO64097.1 - 2e-37 128.7 41.2 3.8e-37 127.8 22.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 AEO64097.1 - 6.8e-07 27.8 4.3 1.1e-06 27.1 3.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PAS PF00989.19 AEO64098.1 - 0.00015 21.5 0.0 0.00036 20.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.13 AEO64098.1 - 0.0017 18.1 8.6 0.004 17.0 6.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavokinase PF01687.12 AEO64099.1 - 9e-33 112.8 0.0 1.1e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase DUF3530 PF12048.3 AEO64099.1 - 0.048 12.6 1.7 0.061 12.2 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) SoxE PF06525.6 AEO64099.1 - 0.2 10.9 2.2 0.28 10.4 1.5 1.1 1 0 0 1 1 1 0 Sulfocyanin (SoxE) SSP160 PF06933.6 AEO64099.1 - 2 6.3 12.5 2.5 5.9 8.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 AEO64099.1 - 10 5.9 17.9 19 5.0 12.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein NAD_binding_10 PF13460.1 AEO64100.1 - 2.8e-12 47.0 0.7 3.6e-12 46.6 0.5 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO64100.1 - 8.3e-10 38.4 0.0 2.3e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 AEO64100.1 - 9.7e-07 28.2 0.0 1.4e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family HIM1 PF08732.5 AEO64100.1 - 4.6e-06 25.3 0.0 1e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 HIM1 NAD_binding_4 PF07993.7 AEO64100.1 - 0.0012 17.7 0.0 0.26 10.1 0.0 2.6 2 1 1 3 3 3 2 Male sterility protein 3Beta_HSD PF01073.14 AEO64100.1 - 0.02 13.5 0.0 0.041 12.5 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family WGG PF10273.4 AEO64101.1 - 4.2e-37 126.0 0.4 8.7e-37 125.0 0.3 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 AEO64101.1 - 0.13 12.2 0.2 0.13 12.2 0.2 2.6 3 0 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) BSD PF03909.12 AEO64102.1 - 6.6e-16 57.7 0.0 1.3e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 BSD domain Sigma70_r2 PF04542.9 AEO64102.1 - 0.074 12.6 0.4 0.27 10.8 0.2 2.0 2 0 0 2 2 2 0 Sigma-70 region 2 Suf PF05843.9 AEO64102.1 - 0.17 11.6 2.7 0.12 12.1 0.2 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PAP1 PF08601.5 AEO64103.1 - 3.1e-55 188.2 6.4 3.1e-55 188.2 4.4 2.2 2 0 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 AEO64103.1 - 5e-09 35.9 13.0 1.1e-08 34.9 9.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AEO64103.1 - 0.0024 17.6 17.3 0.012 15.3 12.0 2.1 1 1 0 1 1 1 1 Basic region leucine zipper Adeno_PIX PF03955.9 AEO64103.1 - 0.006 17.0 1.8 0.006 17.0 1.2 2.6 3 0 0 3 3 3 1 Adenovirus hexon-associated protein (IX) DUF812 PF05667.6 AEO64103.1 - 0.0071 14.9 3.2 0.012 14.2 2.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) FlaC_arch PF05377.6 AEO64103.1 - 0.055 13.3 2.7 0.12 12.3 1.9 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) dsrm PF00035.20 AEO64103.1 - 0.062 13.8 0.3 0.21 12.1 0.2 1.9 1 0 0 1 1 1 0 Double-stranded RNA binding motif DUF972 PF06156.8 AEO64103.1 - 0.066 13.5 1.3 0.21 11.9 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) MbeD_MobD PF04899.7 AEO64103.1 - 0.094 12.6 3.8 0.078 12.8 1.1 2.0 2 0 0 2 2 2 0 MbeD/MobD like DUF904 PF06005.7 AEO64103.1 - 0.11 12.7 8.8 0.3 11.4 6.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) ChaB PF06150.7 AEO64103.1 - 0.13 12.1 0.2 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 ChaB ACCA PF03255.9 AEO64103.1 - 0.16 11.4 1.6 0.29 10.6 1.1 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DivIC PF04977.10 AEO64103.1 - 0.33 10.4 4.3 0.83 9.1 3.0 1.7 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 AEO64103.1 - 0.56 9.7 6.8 1.3 8.5 4.7 1.5 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 AEO64103.1 - 1.6 6.4 2.7 2.1 6.0 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF605 PF04652.11 AEO64105.1 - 6.5 6.0 13.1 7.4 5.8 9.1 1.0 1 0 0 1 1 1 0 Vta1 like BCS1_N PF08740.6 AEO64106.1 - 3.9e-54 183.1 0.3 3.9e-54 183.1 0.2 3.1 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.24 AEO64106.1 - 2.1e-17 63.5 0.0 8e-09 35.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 AEO64106.1 - 0.00034 20.0 0.0 0.00073 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO64106.1 - 0.00072 19.5 0.1 0.0036 17.2 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 AEO64106.1 - 0.00084 19.0 0.1 0.0033 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 AEO64106.1 - 0.0013 19.5 3.9 0.025 15.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 AEO64106.1 - 0.0019 17.2 0.0 0.004 16.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus FAM60A PF15396.1 AEO64106.1 - 0.031 14.0 19.6 0.084 12.6 13.6 1.8 1 0 0 1 1 1 0 Protein Family FAM60A AAA_22 PF13401.1 AEO64106.1 - 0.041 14.0 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Hen1_L PF12623.2 AEO64106.1 - 0.062 12.0 0.0 0.33 9.7 0.0 2.0 2 0 0 2 2 2 0 RNA repair, ligase-Pnkp-associating, region of Hen1 DNA_pol_viral_N PF00242.12 AEO64106.1 - 0.97 8.3 23.5 1.8 7.5 16.3 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain AAA_21 PF13304.1 AEO64106.1 - 1.2 8.9 9.3 0.14 12.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain HMG_CoA_synt_C PF08540.5 AEO64107.1 - 2.9e-99 332.1 0.1 4.1e-99 331.6 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 AEO64107.1 - 5.1e-97 322.4 0.3 7.6e-97 321.8 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal TGT_C2 PF14810.1 AEO64107.1 - 0.013 15.3 0.1 0.062 13.1 0.0 2.0 2 0 0 2 2 2 0 Patch-forming domain C2 of tRNA-guanine transglycosylase PTCB-BRCT PF12738.2 AEO64108.1 - 5.5e-29 99.8 1.3 1.2e-19 69.8 0.2 4.6 6 0 0 6 6 6 3 twin BRCT domain BRCT PF00533.21 AEO64108.1 - 2.2e-24 85.4 0.0 1.3e-08 34.8 0.0 4.9 5 0 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain ESCRT-II PF05871.7 AEO64109.1 - 1.2e-44 151.6 0.0 4.2e-44 149.8 0.0 1.7 1 1 0 1 1 1 1 ESCRT-II complex subunit PXA PF02194.10 AEO64110.1 - 8.3e-54 181.9 0.1 8.3e-54 181.9 0.1 2.0 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 AEO64110.1 - 2.1e-25 88.9 0.0 8e-25 87.1 0.0 2.1 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 AEO64110.1 - 1.1e-21 76.7 0.3 2.9e-21 75.3 0.2 1.8 1 0 0 1 1 1 1 PX domain RGS PF00615.14 AEO64110.1 - 2.4e-09 37.3 0.0 7.8e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain Motilin_assoc PF04643.7 AEO64110.1 - 0.12 11.9 2.8 0.57 9.7 0.1 3.1 4 0 0 4 4 4 0 Motilin/ghrelin-associated peptide RRM_1 PF00076.17 AEO64111.1 - 5.7e-10 38.6 0.0 7.1e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO64111.1 - 8.4e-08 32.0 0.0 1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO64111.1 - 0.0076 16.0 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO64111.1 - 0.014 15.1 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 AEO64112.1 - 0.00024 20.6 0.1 0.00035 20.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO64112.1 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO64112.1 - 0.027 14.4 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) OTT_1508_deam PF14441.1 AEO64113.1 - 6e-11 42.3 0.0 1.2e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase APH PF01636.18 AEO64115.1 - 1.5e-10 41.2 0.4 5.9e-07 29.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 AEO64115.1 - 9e-05 21.9 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Fructosamin_kin PF03881.9 AEO64115.1 - 0.011 14.7 0.0 1.4 7.8 0.0 2.1 1 1 1 2 2 2 0 Fructosamine kinase Choline_kinase PF01633.15 AEO64115.1 - 0.092 12.3 0.0 0.54 9.7 0.0 1.9 1 1 1 2 2 2 0 Choline/ethanolamine kinase DEAD PF00270.24 AEO64116.1 - 1.2e-40 138.8 0.1 1.8e-40 138.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase GST_N_3 PF13417.1 AEO64116.1 - 2.8e-09 37.0 0.0 6.5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 AEO64116.1 - 2.8e-08 33.8 0.0 8.8e-08 32.2 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 AEO64116.1 - 3.7e-08 33.2 0.0 1.2e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 AEO64116.1 - 6.2e-08 32.5 0.0 1.5e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO64116.1 - 1.2e-07 31.4 0.1 4.1e-07 29.7 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Helicase_C PF00271.26 AEO64116.1 - 1.2e-06 28.2 1.5 2.2e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO64116.1 - 5.7e-05 23.0 0.0 0.00017 21.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GST_C_3 PF14497.1 AEO64116.1 - 0.063 13.7 0.0 0.28 11.7 0.0 2.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_47 PF01532.15 AEO64117.1 - 2.8e-137 458.0 0.0 3.2e-137 457.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TipAS PF07739.8 AEO64117.1 - 0.022 15.0 0.1 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Rad10 PF03834.9 AEO64118.1 - 4.2e-31 106.4 0.0 5.9e-31 105.9 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 AEO64118.1 - 0.002 18.2 0.0 0.0046 17.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain MR_MLE_C PF13378.1 AEO64121.1 - 6e-19 68.0 0.2 2.9e-18 65.8 0.0 2.2 3 0 0 3 3 3 1 Enolase C-terminal domain-like MR_MLE PF01188.16 AEO64121.1 - 9.7e-14 51.6 0.1 3.1e-13 50.0 0.0 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 AEO64121.1 - 0.00074 19.4 0.1 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 AEO64121.1 - 0.012 14.6 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus dCMP_cyt_deam_1 PF00383.17 AEO64123.1 - 5.4e-14 51.6 0.0 7.2e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 AEO64123.1 - 0.0069 16.0 0.0 0.0083 15.7 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain BTG PF07742.7 AEO64123.1 - 0.078 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 BTG family XOO_2897-deam PF14440.1 AEO64123.1 - 0.15 11.7 0.2 0.29 10.8 0.1 1.5 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase DnaJ PF00226.26 AEO64124.1 - 4.6e-24 83.9 2.0 4.6e-24 83.9 1.4 2.2 2 0 0 2 2 2 1 DnaJ domain DUF3974 PF13120.1 AEO64124.1 - 0.07 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) PSD5 PF07637.6 AEO64124.1 - 1.3 9.1 4.3 3.5 7.7 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1595) PNPase PF03726.9 AEO64124.1 - 5 7.4 17.0 0.73 10.1 0.3 4.2 4 2 0 4 4 4 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Stn1 PF10451.4 AEO64125.1 - 2.4e-15 56.0 0.2 7.5e-09 34.8 0.1 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 AEO64125.1 - 2.6e-06 27.1 0.1 7.9e-06 25.6 0.1 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Glyco_hydro_81 PF03639.8 AEO64126.1 - 3.7e-211 702.8 0.3 4.3e-211 702.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Pkinase PF00069.20 AEO64127.1 - 3.9e-26 91.7 0.0 5.5e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO64127.1 - 2.6e-15 56.1 0.0 1.8e-14 53.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO64127.1 - 0.056 12.3 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FGGY_C PF02782.11 AEO64128.1 - 6.1e-77 257.7 0.9 1e-76 256.9 0.6 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 AEO64128.1 - 2.8e-63 213.5 0.0 3.8e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain NTP_transferase PF00483.18 AEO64129.1 - 7.4e-48 163.0 0.0 1.7e-47 161.8 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 AEO64129.1 - 2.4e-16 58.4 17.5 2.4e-09 36.2 1.1 4.4 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 AEO64129.1 - 7.6e-11 42.3 0.0 1e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 AEO64129.1 - 6.2e-07 28.8 9.7 8.7e-07 28.3 0.6 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase dsrm PF00035.20 AEO64130.1 - 0.00032 21.1 0.0 0.00063 20.2 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 AEO64130.1 - 0.0038 17.4 0.0 0.009 16.2 0.0 1.7 2 1 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 Prenyltrans PF00432.16 AEO64131.1 - 1.8e-41 139.3 27.3 7e-10 38.2 0.5 6.3 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 AEO64131.1 - 1.5e-23 83.3 0.0 2e-15 57.1 0.0 4.3 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 AEO64131.1 - 4.1e-05 23.5 0.0 0.0014 18.6 0.0 3.0 2 2 1 3 3 3 2 Prenyltransferase-like Zn_clus PF00172.13 AEO64132.1 - 0.0033 17.3 7.7 0.0068 16.2 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KAR9 PF08580.5 AEO64132.1 - 0.79 7.9 21.0 0.011 14.0 4.9 2.2 2 0 0 2 2 2 0 Yeast cortical protein KAR9 MSP1_C PF07462.6 AEO64132.1 - 1.6 7.0 2.5 3.8 5.7 1.7 1.6 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus ubiquitin PF00240.18 AEO64133.1 - 4.8e-136 442.3 23.5 1.1e-33 114.4 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 AEO64133.1 - 2.2e-78 257.9 21.1 4.3e-19 67.9 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AEO64133.1 - 2.6e-24 85.2 11.1 0.00015 21.9 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 AEO64133.1 - 5.2e-22 78.2 1.5 0.00071 19.3 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 AEO64133.1 - 5.2e-14 52.0 2.9 0.13 12.1 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AEO64133.1 - 8.1e-14 51.5 2.4 0.13 12.5 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 AEO64133.1 - 9.7e-11 41.5 0.0 1.5 8.8 0.0 4.9 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 AEO64133.1 - 1.6e-06 27.9 5.8 4.5 7.2 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 AEO64133.1 - 5.3e-06 25.7 0.5 2 7.5 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase FlgD_ig PF13860.1 AEO64133.1 - 6.8e-05 22.5 5.3 14 5.5 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 AEO64133.1 - 0.00045 18.6 13.5 2.3 6.4 0.2 5.7 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 AEO64133.1 - 0.0011 18.4 0.0 48 3.3 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 AEO64133.1 - 0.0019 18.5 0.6 1e+02 3.3 0.0 4.2 4 0 0 4 4 4 0 ACT domain DUF3861 PF12977.2 AEO64133.1 - 0.0055 16.7 5.2 53 4.0 0.0 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 AEO64133.1 - 0.023 14.5 14.3 7.9 6.4 0.2 4.4 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 AEO64133.1 - 0.026 14.4 29.1 3.5 7.7 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 AEO64133.1 - 0.037 14.0 7.8 44 4.1 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 AEO64133.1 - 0.071 13.1 12.4 42 4.2 0.1 5.9 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 AEO64133.1 - 0.4 10.6 7.4 1e+02 2.9 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Myosin_N PF02736.14 AEO64133.1 - 1.8 8.2 8.3 1e+02 2.7 0.1 4.7 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain CDC48_2 PF02933.12 AEO64133.1 - 9.3 5.9 12.2 70 3.1 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 BRAP2 PF07576.7 AEO64134.1 - 1.2e-20 73.0 0.0 2e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 AEO64134.1 - 1.8e-16 59.9 8.5 1.8e-16 59.9 5.9 2.7 3 0 0 3 3 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 AEO64134.1 - 3.1e-09 36.5 9.7 3.1e-09 36.5 6.7 2.0 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 AEO64134.1 - 0.00012 21.7 7.0 0.00012 21.7 4.8 2.3 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AEO64134.1 - 0.00019 20.9 8.0 0.00049 19.7 5.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO64134.1 - 0.0022 17.5 6.7 0.0022 17.5 4.7 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO64134.1 - 0.0041 17.1 8.6 0.0041 17.1 6.0 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO64134.1 - 0.0043 17.1 5.7 0.0043 17.1 4.0 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 AEO64134.1 - 0.0051 16.5 2.7 0.011 15.5 1.8 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 AEO64134.1 - 0.08 12.6 5.5 0.065 12.9 1.0 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-Apc11 PF12861.2 AEO64134.1 - 0.15 11.9 5.7 0.42 10.4 3.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FlgN PF05130.7 AEO64134.1 - 5.6 7.2 18.0 1.3 9.2 8.6 2.2 2 0 0 2 2 2 0 FlgN protein Acyltransferase PF01553.16 AEO64135.1 - 7.1e-10 38.4 0.0 0.00017 21.0 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase Cwf_Cwc_15 PF04889.7 AEO64137.1 - 0.082 12.6 11.2 0.99 9.0 7.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PBP_sp32 PF07222.7 AEO64137.1 - 0.12 11.5 3.7 0.2 10.7 2.6 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Nop14 PF04147.7 AEO64137.1 - 0.14 10.0 11.9 0.24 9.2 8.3 1.3 1 0 0 1 1 1 0 Nop14-like family DUF3246 PF11596.3 AEO64137.1 - 0.65 9.2 3.4 0.16 11.1 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Pox_Ag35 PF03286.9 AEO64137.1 - 0.7 9.3 19.2 0.021 14.3 6.5 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PBP1_TM PF14812.1 AEO64137.1 - 2.9 8.2 26.8 0.2 11.9 3.2 3.0 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PGA2 PF07543.7 AEO64137.1 - 5.4 6.8 14.9 2.4 7.9 8.1 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 RNase_H2_suC PF08615.6 AEO64137.1 - 9.4 6.0 7.6 2e+02 1.7 5.3 2.3 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Suc_Fer-like PF06999.7 AEO64138.1 - 1.1e-33 117.1 0.0 1.9e-33 116.4 0.0 1.4 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Drf_GBD PF06371.8 AEO64139.1 - 2e-14 53.3 0.1 1.6e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain WWbp PF10349.4 AEO64141.1 - 1.3e-14 55.1 8.5 1.9e-14 54.5 5.9 1.2 1 0 0 1 1 1 1 WW-domain ligand protein DUF2360 PF10152.4 AEO64141.1 - 0.083 13.1 2.0 0.12 12.7 1.4 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) UCR_hinge PF02320.11 AEO64143.1 - 1.2e-28 98.8 6.1 2.3e-28 97.8 4.2 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Myc_N PF01056.13 AEO64143.1 - 0.048 12.8 10.5 0.051 12.7 7.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF1510 PF07423.6 AEO64143.1 - 0.67 9.2 16.8 0.75 9.1 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 AEO64143.1 - 0.68 7.8 6.9 0.68 7.9 4.8 1.0 1 0 0 1 1 1 0 CDC45-like protein TLP-20 PF06088.6 AEO64143.1 - 1.1 8.9 4.9 1.4 8.5 3.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) eIF-3c_N PF05470.7 AEO64143.1 - 1.3 7.0 6.9 1.5 6.8 4.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Pet191_N PF10203.4 AEO64143.1 - 2.1 8.4 6.6 0.64 10.0 1.9 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 SAPS PF04499.10 AEO64143.1 - 2.5 6.6 6.2 2.8 6.4 4.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.6 AEO64143.1 - 2.6 6.0 6.8 3 5.8 4.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PBP1_TM PF14812.1 AEO64143.1 - 3.8 7.8 6.9 5.6 7.3 4.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.9 AEO64143.1 - 3.9 6.9 12.1 4.9 6.6 8.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Daxx PF03344.10 AEO64143.1 - 4.3 5.7 20.5 5 5.4 14.2 1.0 1 0 0 1 1 1 0 Daxx Family IncA PF04156.9 AEO64143.1 - 4.8 6.7 9.4 6 6.4 6.5 1.1 1 0 0 1 1 1 0 IncA protein DDHD PF02862.12 AEO64143.1 - 5.6 6.6 6.3 6.7 6.4 4.4 1.2 1 0 0 1 1 1 0 DDHD domain Na_trans_assoc PF06512.8 AEO64143.1 - 5.6 6.8 15.2 6.7 6.6 10.6 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Tim54 PF11711.3 AEO64143.1 - 7.7 5.0 13.2 8.9 4.7 9.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EBV-NA3 PF05009.7 AEO64143.1 - 7.7 5.6 9.8 10 5.2 6.8 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Spore_coat_CotO PF14153.1 AEO64143.1 - 8.1 5.8 15.3 10 5.4 10.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF3530 PF12048.3 AEO64143.1 - 8.3 5.2 11.9 9.8 5.0 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Asp-B-Hydro_N PF05279.6 AEO64143.1 - 8.8 6.1 19.8 11 5.7 13.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region adh_short PF00106.20 AEO64144.1 - 0.01 15.7 0.1 0.24 11.2 0.0 2.8 3 0 0 3 3 3 0 short chain dehydrogenase Acetyltransf_10 PF13673.1 AEO64146.1 - 4.3e-09 36.5 0.0 0.00011 22.2 0.0 3.3 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO64146.1 - 2.6e-08 33.8 0.0 1.1e-07 31.9 0.0 2.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Zn_clus PF00172.13 AEO64146.1 - 4.1e-08 33.0 9.8 4.1e-08 33.0 6.8 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.19 AEO64146.1 - 1.2e-07 31.6 0.0 6e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Fungal_trans_2 PF11951.3 AEO64146.1 - 0.00014 20.6 2.2 0.00021 20.0 1.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_9 PF13527.1 AEO64146.1 - 0.00015 21.6 0.0 0.00033 20.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO64146.1 - 0.014 15.1 0.0 0.041 13.6 0.0 1.8 1 0 0 1 1 1 0 FR47-like protein TctC PF03401.9 AEO64146.1 - 0.025 13.5 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor Acetyltransf_CG PF14542.1 AEO64146.1 - 0.033 14.0 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Fungal_trans PF04082.13 AEO64147.1 - 3.2e-23 81.9 0.0 5.6e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_60s PF00428.14 AEO64147.1 - 6.4 7.2 10.9 24 5.4 5.1 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein MFS_1 PF07690.11 AEO64148.1 - 3.1e-42 144.5 51.1 1.3e-41 142.5 34.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO64148.1 - 2.6e-12 45.7 17.9 3.5e-12 45.3 12.1 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RXT2_N PF08595.6 AEO64149.1 - 5.3e-41 139.8 0.0 5.3e-41 139.8 0.0 2.0 3 0 0 3 3 3 1 RXT2-like, N-terminal CM_2 PF01817.16 AEO64149.1 - 0.058 13.4 0.7 3.3 7.8 0.1 2.4 2 0 0 2 2 2 0 Chorismate mutase type II Phage_GPD PF05954.6 AEO64152.1 - 0.14 11.3 5.7 0.21 10.7 4.0 1.5 1 1 0 1 1 1 0 Phage late control gene D protein (GPD) SKG6 PF08693.5 AEO64153.1 - 3.1e-07 29.5 0.7 3.1e-07 29.5 0.5 2.3 3 0 0 3 3 3 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 AEO64153.1 - 0.00058 19.5 0.0 0.00058 19.5 0.0 1.8 2 0 0 2 2 2 1 TMEM154 protein family IncA PF04156.9 AEO64153.1 - 0.0073 15.9 0.0 0.0099 15.4 0.0 1.2 1 0 0 1 1 1 1 IncA protein DUF4448 PF14610.1 AEO64153.1 - 0.018 14.5 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PsaL PF02605.10 AEO64153.1 - 0.036 13.6 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI BatD PF13584.1 AEO64153.1 - 0.063 11.8 0.0 0.093 11.3 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance Sec66 PF09802.4 AEO64153.1 - 0.18 11.1 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 YajC PF02699.10 AEO64153.1 - 0.22 11.2 0.3 0.34 10.6 0.2 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit CcmD PF04995.9 AEO64153.1 - 0.34 10.6 3.5 0.63 9.8 2.5 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) SIR2 PF02146.12 AEO64154.1 - 1.7e-39 135.3 0.0 2.8e-39 134.6 0.0 1.3 1 1 0 1 1 1 1 Sir2 family Pkinase_Tyr PF07714.12 AEO64155.1 - 3.5e-13 49.2 0.0 4.5e-13 48.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 AEO64155.1 - 4.2e-11 42.4 0.0 4.7e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 AEO64155.1 - 1.9e-06 27.0 0.0 2.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO64155.1 - 0.03 14.0 0.5 2.2 7.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_16 PF00722.16 AEO64156.1 - 2.4e-44 150.8 0.6 2.4e-44 150.8 0.4 1.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Tyrosinase PF00264.15 AEO64157.1 - 9.3e-22 78.2 0.6 2.5e-21 76.8 0.4 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase DHDPS PF00701.17 AEO64158.1 - 2.3e-39 134.7 0.0 6.2e-29 100.4 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family HTH_29 PF13551.1 AEO64158.1 - 0.013 15.6 0.3 1.9 8.6 0.0 3.2 3 0 0 3 3 3 0 Winged helix-turn helix Sporozoite_P67 PF05642.6 AEO64158.1 - 0.094 10.5 1.1 0.094 10.5 0.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3439 PF11921.3 AEO64158.1 - 3.5 7.3 15.3 6.8 6.4 10.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 AEO64158.1 - 4.3 5.2 14.1 7 4.4 9.8 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dfp1_Him1_M PF08630.5 AEO64160.1 - 1.3e-42 144.5 0.0 3e-42 143.3 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 AEO64160.1 - 3.4e-25 87.4 0.5 5.8e-25 86.7 0.4 1.4 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 AEO64160.1 - 0.0049 16.9 0.0 0.022 14.8 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AEO64160.1 - 0.0058 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Peptidase_M24 PF00557.19 AEO64161.1 - 2.9e-48 164.1 0.1 4.4e-48 163.6 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 AEO64161.1 - 1.8e-34 117.9 0.0 3.8e-34 116.9 0.0 1.5 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain HLH PF00010.21 AEO64162.1 - 2.8e-16 58.9 0.0 2.2e-15 56.0 0.0 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain APG12 PF04110.8 AEO64163.1 - 3.7e-25 87.9 0.0 4.7e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 AEO64163.1 - 0.00021 21.2 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.10 AEO64164.1 - 1.3e-105 352.2 0.4 1.5e-105 352.0 0.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 AEO64164.1 - 3.8e-11 42.6 0.5 5.6e-11 42.1 0.3 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase UQ_con PF00179.21 AEO64165.1 - 1.1e-36 125.2 0.0 1.5e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AEO64165.1 - 0.086 12.7 0.1 0.16 11.9 0.1 1.7 1 1 0 1 1 1 0 RWD domain DUF572 PF04502.8 AEO64166.1 - 1.2e-49 169.2 0.0 1.4e-49 169.0 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF1778 PF08681.6 AEO64166.1 - 0.00067 19.4 0.2 0.0016 18.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1778) Glyco_hydro_43 PF04616.9 AEO64167.1 - 3.1e-69 233.2 7.0 3.8e-69 232.9 4.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PD40 PF07676.7 AEO64167.1 - 0.039 13.6 2.4 0.095 12.3 0.6 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat p450 PF00067.17 AEO64168.1 - 3e-29 101.8 0.0 4.1e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PT-TG PF14449.1 AEO64168.1 - 0.1 12.3 0.1 0.54 10.0 0.1 2.0 2 0 0 2 2 2 0 Pre-toxin TG Lactamase_B_2 PF12706.2 AEO64169.1 - 1.2e-10 41.2 0.0 3.4e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DRMBL PF07522.9 AEO64169.1 - 2.7e-06 27.3 0.0 6.4e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.22 AEO64169.1 - 0.00078 19.1 0.1 0.0021 17.7 0.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 AEO64169.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase Velvet PF11754.3 AEO64171.1 - 2.9e-51 173.9 0.8 7.2e-51 172.6 0.5 1.6 1 1 0 1 1 1 1 Velvet factor 7TM_GPCR_Sra PF02117.11 AEO64172.1 - 0.11 11.1 0.3 0.12 10.9 0.2 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra HET PF06985.6 AEO64174.1 - 6.9e-37 126.7 0.0 1.1e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) YTH PF04146.10 AEO64176.1 - 6.9e-41 139.1 0.0 1.1e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain Glyco_hydro_61 PF03443.9 AEO64177.1 - 8.6e-85 283.9 0.1 8.6e-85 283.9 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 F-box-like PF12937.2 AEO64178.1 - 6.1e-05 22.6 0.0 0.00018 21.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO64178.1 - 0.015 14.9 0.1 0.034 13.7 0.1 1.6 1 0 0 1 1 1 0 F-box domain DUF2456 PF10445.4 AEO64179.1 - 5.4e-08 32.6 0.7 1.2e-07 31.5 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) DUF2627 PF11118.3 AEO64179.1 - 0.18 11.9 5.4 0.24 11.5 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) Mannosyl_trans2 PF04188.8 AEO64180.1 - 5.3e-62 210.1 0.6 9.6e-62 209.3 0.4 1.4 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) SR-25 PF10500.4 AEO64182.1 - 0.16 11.4 4.3 0.24 10.8 3.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glyco_hydro_2_C PF02836.12 AEO64183.1 - 4.4e-101 337.6 0.0 6e-101 337.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 AEO64183.1 - 3.1e-49 167.4 0.0 4.7e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 AEO64183.1 - 2.7e-44 150.6 0.1 4.9e-44 149.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 AEO64183.1 - 6.4e-12 45.9 0.0 1.3e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 CBM_1 PF00734.13 AEO64184.1 - 4.4e-15 55.0 14.1 1.1e-14 53.7 9.8 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.15 AEO64184.1 - 6.2e-14 49.5 31.1 0.084 12.7 0.1 10.2 9 0 0 9 9 9 8 BNR/Asp-box repeat Hira PF07569.6 AEO64186.1 - 7.7e-85 283.5 0.0 1.7e-84 282.4 0.0 1.6 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 AEO64186.1 - 1.2e-39 132.7 25.5 7e-07 28.8 0.1 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat HIRA_B PF09453.5 AEO64186.1 - 9.6e-11 40.9 0.6 2e-10 39.9 0.4 1.6 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 AEO64186.1 - 0.00078 19.0 0.4 37 4.1 0.0 4.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 AEO64186.1 - 0.34 8.6 0.1 1.5 6.5 0.0 2.0 3 0 0 3 3 3 0 IKI3 family Acetyltransf_1 PF00583.19 AEO64189.1 - 1.2e-07 31.6 0.0 2.4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO64189.1 - 3.3e-06 27.1 0.0 5.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO64189.1 - 0.0005 20.1 0.1 0.00079 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO64189.1 - 0.0045 16.7 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 AEO64189.1 - 0.02 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FtsJ PF01728.14 AEO64190.1 - 2.8e-60 203.4 0.0 3.5e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.24 AEO64191.1 - 1.3e-41 141.8 0.2 4.6e-41 140.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO64191.1 - 2.7e-24 84.8 0.0 5.4e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AEO64191.1 - 0.00021 20.2 0.0 0.00032 19.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 AEO64191.1 - 0.082 13.0 0.0 0.34 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain Flavoprotein PF02441.14 AEO64193.1 - 8.8e-18 64.2 0.1 1.4e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein F-box-like PF12937.2 AEO64193.1 - 0.02 14.6 0.0 0.092 12.4 0.0 2.2 1 0 0 1 1 1 0 F-box-like Hexapep PF00132.19 AEO64194.1 - 1.1e-09 37.3 11.6 1.1e-05 24.6 3.4 3.8 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AEO64194.1 - 0.0018 17.7 12.3 2.3 7.8 3.2 3.7 2 1 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase DUF4440 PF14534.1 AEO64194.1 - 0.16 12.1 2.7 13 5.9 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4440) Ribosomal_60s PF00428.14 AEO64194.1 - 1.1 9.6 8.0 2.2 8.7 5.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Complex1_51K PF01512.12 AEO64195.1 - 5.1e-46 156.1 0.0 8.3e-46 155.4 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 AEO64195.1 - 1.9e-17 62.1 1.0 1.9e-17 62.1 0.7 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 AEO64195.1 - 1.1e-09 38.0 0.0 4.6e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 SLBB domain PDDEXK_1 PF12705.2 AEO64196.1 - 0.014 14.8 0.5 0.43 9.9 0.1 2.3 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily FdhE PF04216.7 AEO64196.1 - 0.14 11.8 3.2 0.26 10.9 2.2 1.4 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Nop14 PF04147.7 AEO64197.1 - 0.17 9.7 12.7 0.28 9.0 8.8 1.3 1 0 0 1 1 1 0 Nop14-like family PBP_sp32 PF07222.7 AEO64197.1 - 0.18 10.9 4.7 0.32 10.1 3.3 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pox_Ag35 PF03286.9 AEO64197.1 - 0.7 9.3 18.8 0.022 14.2 6.3 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CDC27 PF09507.5 AEO64197.1 - 0.83 8.8 23.3 0.13 11.4 6.3 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 PBP1_TM PF14812.1 AEO64197.1 - 3.5 8.0 27.3 0.32 11.3 3.7 3.0 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PGA2 PF07543.7 AEO64197.1 - 5.2 6.8 15.4 2.4 7.9 8.5 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 Dpy19 PF10034.4 AEO64199.1 - 0.23 9.6 1.2 0.26 9.4 0.8 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF1072 PF06380.6 AEO64200.1 - 0.15 11.7 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) SRP40_C PF05022.7 AEO64201.1 - 2.2e-26 92.1 0.6 6.4e-26 90.6 0.4 1.9 1 0 0 1 1 1 1 SRP40, C-terminal domain A_deaminase PF00962.17 AEO64202.1 - 1.1e-43 149.4 0.0 2.7e-40 138.3 0.0 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase A_deaminase_N PF08451.6 AEO64202.1 - 0.0029 17.6 0.3 0.026 14.5 0.2 2.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase N-terminal FliG_M PF14841.1 AEO64202.1 - 0.085 12.8 1.2 0.24 11.4 0.1 2.2 2 0 0 2 2 2 0 FliG middle domain FTA2 PF13095.1 AEO64203.1 - 1.6e-33 116.0 0.0 2e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 TPPK_C PF12555.3 AEO64204.1 - 0.2 11.4 7.8 0.26 11.0 5.4 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal bZIP_1 PF00170.16 AEO64205.1 - 1.1e-12 47.7 2.1 1.6e-12 47.1 1.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AEO64205.1 - 8.7e-06 25.4 8.6 1.4e-05 24.7 5.9 1.2 1 0 0 1 1 1 1 Basic region leucine zipper Ndc1_Nup PF09531.5 AEO64205.1 - 0.71 8.2 2.2 0.97 7.7 1.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ABC_tran PF00005.22 AEO64208.1 - 4.7e-50 169.4 0.6 1.3e-23 83.7 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 AEO64208.1 - 8.4e-21 73.6 6.6 8.4e-21 73.6 4.6 4.1 4 1 1 5 5 4 1 ABC transporter AAA_21 PF13304.1 AEO64208.1 - 1e-18 68.3 0.0 5.9e-05 23.1 0.0 4.5 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 AEO64208.1 - 2.6e-10 39.8 6.3 0.00078 18.7 0.0 4.6 5 0 0 5 5 4 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 AEO64208.1 - 2.7e-09 37.8 0.5 0.0033 18.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 AEO64208.1 - 3.3e-07 30.6 1.3 0.013 15.8 0.0 3.6 5 0 0 5 5 3 2 AAA domain MMR_HSR1 PF01926.18 AEO64208.1 - 5e-07 29.6 0.0 0.0044 16.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 AEO64208.1 - 1.1e-06 27.9 3.0 0.75 8.7 0.0 4.4 4 2 0 4 4 4 3 AAA ATPase domain Miro PF08477.8 AEO64208.1 - 1.4e-06 28.7 0.0 0.012 16.0 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 AEO64208.1 - 1.5e-06 27.6 0.1 0.017 14.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 AEO64208.1 - 4.3e-06 26.0 0.1 0.032 13.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 AEO64208.1 - 1.6e-05 25.0 0.1 0.25 11.4 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 AEO64208.1 - 2e-05 24.5 0.0 0.22 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AEO64208.1 - 2.9e-05 24.1 1.5 0.041 13.8 0.1 3.0 3 0 0 3 3 2 2 AAA ATPase domain MobB PF03205.9 AEO64208.1 - 4.5e-05 23.1 0.3 0.18 11.4 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 AEO64208.1 - 4.6e-05 23.2 2.3 0.7 9.6 0.0 4.1 4 1 0 4 4 4 2 Dynamin family ArgK PF03308.11 AEO64208.1 - 0.00024 19.9 0.4 0.68 8.6 0.0 2.6 2 0 0 2 2 2 2 ArgK protein AAA PF00004.24 AEO64208.1 - 0.00028 21.0 0.0 0.55 10.4 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 AEO64208.1 - 0.00029 20.8 4.4 0.036 14.0 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 AEO64208.1 - 0.0017 18.2 0.0 1.4 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 AEO64208.1 - 0.0018 17.7 0.5 3.9 6.8 0.0 3.8 4 0 0 4 4 4 1 AAA-like domain AAA_23 PF13476.1 AEO64208.1 - 0.0021 18.4 17.3 0.038 14.3 0.0 4.7 5 0 0 5 5 5 2 AAA domain NACHT PF05729.7 AEO64208.1 - 0.0022 17.7 0.6 2.6 7.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain NTPase_1 PF03266.10 AEO64208.1 - 0.0024 17.5 0.0 0.72 9.5 0.0 2.7 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.17 AEO64208.1 - 0.0041 17.2 0.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ATP-synt_ab PF00006.20 AEO64208.1 - 0.0064 16.0 0.1 0.7 9.3 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 AEO64208.1 - 0.0067 16.3 1.0 5.7 6.9 0.2 4.0 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.14 AEO64208.1 - 0.0078 15.6 0.5 1.5 8.2 0.3 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 AEO64208.1 - 0.01 14.7 0.0 2.1 7.1 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain T2SE PF00437.15 AEO64208.1 - 0.012 14.5 0.0 0.11 11.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.1 AEO64208.1 - 0.014 14.8 0.0 6.3 6.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.9 AEO64208.1 - 0.027 14.2 0.3 4.5 6.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 AEO64208.1 - 0.051 13.0 1.1 3.2 7.1 0.0 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 AEO64208.1 - 0.061 12.8 0.1 8.7 5.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 AEO64208.1 - 3.7 7.1 7.2 24 4.5 0.0 3.5 4 0 0 4 4 4 0 Archaeal ATPase Tubulin PF00091.20 AEO64209.1 - 2.7e-70 236.5 0.0 4.6e-70 235.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AEO64209.1 - 4.3e-49 165.7 0.1 6.5e-49 165.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 AEO64209.1 - 9.5e-06 25.6 0.0 2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 AEO64209.1 - 0.003 17.0 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain bZIP_1 PF00170.16 AEO64210.1 - 1.1e-05 25.3 6.9 1.7e-05 24.6 4.8 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AEO64210.1 - 0.0013 18.5 7.2 0.002 17.8 5.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper SR-25 PF10500.4 AEO64210.1 - 0.032 13.7 4.6 0.047 13.1 3.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein bZIP_Maf PF03131.12 AEO64210.1 - 0.076 13.3 3.2 0.11 12.8 2.2 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor SOBP PF15279.1 AEO64210.1 - 0.9 9.8 19.2 1.4 9.1 13.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein TPR_MLP1_2 PF07926.7 AEO64211.1 - 2.3e-30 105.0 31.7 2.3e-30 105.0 22.0 17.1 5 3 11 16 16 16 4 TPR/MLP1/MLP2-like protein CALCOCO1 PF07888.6 AEO64211.1 - 4.9e-05 21.8 29.9 4.9e-05 21.8 20.7 10.4 2 2 6 9 9 9 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4200 PF13863.1 AEO64211.1 - 0.0002 21.3 5.6 0.0002 21.3 3.9 20.5 9 4 9 20 20 20 3 Domain of unknown function (DUF4200) DUF1664 PF07889.7 AEO64211.1 - 0.0014 18.4 4.0 0.0014 18.4 2.8 16.3 9 4 9 19 19 19 4 Protein of unknown function (DUF1664) ADIP PF11559.3 AEO64211.1 - 0.0034 17.2 14.7 0.0034 17.2 10.2 19.9 7 5 12 20 20 20 5 Afadin- and alpha -actinin-Binding PAM2 PF07145.10 AEO64211.1 - 0.05 13.1 0.2 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region IL11 PF07400.6 AEO64211.1 - 0.86 9.1 4.5 10 5.6 0.0 4.3 3 1 0 3 3 3 0 Interleukin 11 DUF3948 PF13134.1 AEO64212.1 - 0.12 11.8 1.1 0.43 10.0 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) Squash PF00299.13 AEO64212.1 - 1.7 8.5 8.8 15 5.4 0.3 3.3 3 0 0 3 3 3 0 Squash family serine protease inhibitor DOPA_dioxygen PF08883.6 AEO64213.1 - 3.3e-31 107.4 0.0 4.1e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Terpene_synth_C PF03936.11 AEO64214.1 - 6.1e-15 55.1 0.0 1.5e-14 53.9 0.0 1.6 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain DUF697 PF05128.7 AEO64214.1 - 0.035 13.5 0.8 0.67 9.4 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF697) DUF3431 PF11913.3 AEO64214.1 - 0.049 13.0 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3431) CheZ PF04344.8 AEO64214.1 - 0.089 12.4 0.2 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ BHD_1 PF10403.4 AEO64215.1 - 0.048 13.1 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 WD40 PF00400.27 AEO64216.1 - 1.3e-49 164.3 23.7 5.8e-12 44.9 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 AEO64216.1 - 1e-05 25.3 13.6 0.0096 15.6 0.2 4.3 2 2 2 4 4 4 2 Transcription factor IIIC subunit delta N-term YmzC PF14157.1 AEO64216.1 - 0.0063 16.3 0.0 1.9 8.3 0.0 3.5 4 0 0 4 4 4 1 YmzC-like protein IKI3 PF04762.7 AEO64216.1 - 0.013 13.3 4.3 0.057 11.2 0.0 2.1 2 0 0 2 2 2 0 IKI3 family Kelch_6 PF13964.1 AEO64216.1 - 0.046 13.9 0.3 0.69 10.1 0.0 2.9 3 0 0 3 3 3 0 Kelch motif GSDH PF07995.6 AEO64217.1 - 4.9e-05 22.5 0.0 0.00011 21.3 0.0 1.7 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 AEO64217.1 - 0.004 16.5 0.0 0.0095 15.3 0.0 1.7 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region DGF-1_C PF11040.3 AEO64217.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.4 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DHDPS PF00701.17 AEO64218.1 - 1.4e-33 115.7 0.0 1.7e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family 5_3_exonuc_N PF02739.11 AEO64218.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain DUF1604 PF07713.8 AEO64220.1 - 9e-40 134.3 2.0 2.7e-39 132.8 1.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 AEO64220.1 - 8.4e-06 25.4 0.4 8.4e-06 25.4 0.3 2.5 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.2 AEO64220.1 - 0.0033 17.2 0.1 0.0033 17.2 0.1 3.0 3 2 0 3 3 3 1 DExH-box splicing factor binding site Pkinase PF00069.20 AEO64221.1 - 4.1e-68 229.3 0.0 6.4e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO64221.1 - 2.1e-35 122.0 0.0 7.9e-35 120.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 AEO64221.1 - 1.6e-17 62.6 0.1 2.9e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 AEO64221.1 - 6.9e-07 28.5 0.1 1.2e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AEO64221.1 - 0.00011 21.2 0.0 0.00017 20.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO64221.1 - 0.00036 20.3 0.1 0.001 18.8 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 AEO64221.1 - 0.0078 15.4 0.1 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 AEO64221.1 - 0.025 13.9 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 AEO64221.1 - 0.026 13.8 0.1 0.057 12.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 AEO64221.1 - 0.051 13.1 0.1 0.089 12.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1180 PF06679.7 AEO64222.1 - 0.0009 19.1 0.3 0.00097 19.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) UvrD_C PF13361.1 AEO64223.1 - 3.3e-72 243.8 0.0 4.5e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 AEO64223.1 - 3.7e-63 213.7 0.1 1.7e-61 208.2 0.0 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 AEO64223.1 - 1.1e-13 51.2 0.0 4.2e-13 49.3 0.0 2.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 AEO64223.1 - 9.4e-12 44.5 1.7 3.3e-11 42.7 0.7 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 AEO64223.1 - 4.3e-07 29.7 0.8 0.00014 21.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 AEO64223.1 - 0.00019 21.0 0.0 1.9 7.9 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 AEO64223.1 - 0.00053 19.4 0.0 0.011 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 AEO64223.1 - 0.024 14.1 0.0 0.13 11.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain SAP18 PF06487.7 AEO64223.1 - 0.077 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) DUF2014 PF09427.5 AEO64225.1 - 8.1e-111 369.3 3.2 1.2e-110 368.7 2.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 AEO64225.1 - 2.8e-17 62.1 0.6 5.5e-17 61.2 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PBP1_TM PF14812.1 AEO64225.1 - 0.53 10.6 5.6 1.4 9.2 3.9 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 AEO64225.1 - 1.2 7.0 6.0 1.9 6.4 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Glucosamine_iso PF01182.15 AEO64226.1 - 2.3e-26 92.7 0.0 4e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_2 PF03727.11 AEO64227.1 - 3.2e-32 111.6 0.0 2.7e-26 92.2 0.0 2.3 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 AEO64227.1 - 2.3e-28 98.9 0.0 3.3e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase NDT80_PhoG PF05224.7 AEO64228.1 - 1.1e-33 116.8 0.0 1.8e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF605 PF04652.11 AEO64228.1 - 0.06 12.7 12.8 0.078 12.3 8.9 1.2 1 0 0 1 1 1 0 Vta1 like Glyco_hydro_3 PF00933.16 AEO64229.1 - 4.6e-54 183.4 0.0 7e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fe_hyd_SSU PF02256.12 AEO64229.1 - 0.00017 21.5 0.3 0.043 13.8 0.0 3.1 3 0 0 3 3 3 1 Iron hydrogenase small subunit Acetyltransf_1 PF00583.19 AEO64229.1 - 0.0017 18.3 0.0 0.01 15.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.17 AEO64229.1 - 0.0033 16.9 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_7 PF13508.1 AEO64229.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Amidohydro_4 PF13147.1 AEO64230.1 - 3.1e-14 53.6 0.6 9.8e-06 25.7 0.0 2.5 1 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 AEO64230.1 - 3e-09 36.9 0.0 1.1e-08 35.1 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 AEO64230.1 - 3.4e-07 29.8 0.0 2e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 AEO64230.1 - 1.7e-05 24.5 0.0 5.4e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase Ceramidase_alk PF04734.8 AEO64231.1 - 2.9e-287 954.0 0.0 3.3e-287 953.9 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase MFS_1 PF07690.11 AEO64232.1 - 2.1e-45 154.9 42.1 2.1e-45 154.9 29.2 2.3 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO64232.1 - 2.1e-18 65.8 11.7 5.2e-18 64.5 8.1 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 AEO64232.1 - 5.1e-12 45.1 14.0 5.1e-12 45.1 9.7 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Pkinase PF00069.20 AEO64234.1 - 4.4e-24 85.0 0.0 6e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO64234.1 - 6.5e-20 71.2 0.0 8.6e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO64234.1 - 0.00022 20.3 0.0 0.00031 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AEO64234.1 - 0.00023 20.2 0.0 0.00048 19.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO64234.1 - 0.00046 19.9 0.4 0.018 14.7 0.1 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 AEO64234.1 - 0.0027 17.0 0.0 0.0078 15.5 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Rcd1 PF04078.8 AEO64235.1 - 2.4e-131 436.3 5.2 2.9e-131 436.0 3.6 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like OSCP PF00213.13 AEO64235.1 - 0.097 12.5 1.1 1.6 8.5 0.0 2.6 3 0 0 3 3 3 0 ATP synthase delta (OSCP) subunit V-ATPase_H_N PF03224.9 AEO64235.1 - 0.3 10.1 3.4 11 5.0 2.1 2.9 1 1 0 1 1 1 0 V-ATPase subunit H DnaJ_CXXCXGXG PF00684.14 AEO64236.1 - 0.031 14.3 9.2 2.4 8.2 0.9 4.3 2 1 3 5 5 5 0 DnaJ central domain HTH_psq PF05225.11 AEO64238.1 - 1.1e-05 24.8 0.0 2.2e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain Na_H_Exchanger PF00999.16 AEO64239.1 - 6.5e-56 189.4 46.4 1.7e-54 184.7 32.2 2.0 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Med21 PF11221.3 AEO64239.1 - 0.82 9.6 1.6 3.1 7.7 0.7 2.0 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Pyr_redox_2 PF07992.9 AEO64240.1 - 8.1e-32 110.7 0.0 2.5e-31 109.1 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.17 AEO64240.1 - 9.4e-30 103.0 0.0 1.9e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.22 AEO64240.1 - 1.2e-18 67.2 5.2 1.1e-17 64.1 0.2 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 AEO64240.1 - 1.4e-15 57.0 2.1 1.2e-12 47.6 2.3 2.8 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.1 AEO64240.1 - 1.2e-12 47.4 0.0 3.1e-05 23.6 0.0 2.9 3 0 0 3 3 3 2 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.12 AEO64240.1 - 4.5e-10 39.0 0.0 9.3e-10 37.9 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.21 AEO64240.1 - 1.3e-09 37.5 0.5 7.8e-09 34.9 0.1 2.6 2 1 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 AEO64240.1 - 3.9e-07 30.3 0.0 0.00054 20.0 0.0 3.2 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO64240.1 - 5e-05 23.1 0.3 1.1 9.0 0.0 3.5 2 1 1 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 AEO64240.1 - 0.00037 19.5 8.6 0.63 8.8 0.0 5.0 5 1 1 6 6 6 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 AEO64240.1 - 0.00071 18.5 0.0 0.0037 16.2 0.0 2.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 AEO64240.1 - 0.0016 18.6 0.2 0.53 10.5 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.9 AEO64240.1 - 0.0032 15.9 0.1 2.6 6.4 0.0 3.5 3 1 0 4 4 4 1 HI0933-like protein NAD_binding_8 PF13450.1 AEO64240.1 - 0.088 12.8 1.4 0.32 11.0 0.2 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 AEO64240.1 - 0.21 11.6 0.8 15 5.6 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain Pyridox_ox_2 PF12900.2 AEO64242.1 - 9.2e-40 135.7 0.0 1.3e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Spermine_synth PF01564.12 AEO64243.1 - 3.8e-08 32.5 0.0 5.6e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 AEO64243.1 - 1.1e-05 25.3 1.2 2.8e-05 24.0 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO64243.1 - 0.0028 17.4 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO64243.1 - 0.0096 16.4 0.0 0.023 15.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PEMT PF04191.8 AEO64244.1 - 1.3e-30 105.6 4.4 1.3e-30 105.6 3.0 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 AEO64244.1 - 0.12 12.0 0.7 0.46 10.2 0.1 1.9 1 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase Nramp PF01566.13 AEO64245.1 - 2.2e-87 293.2 17.5 3.9e-87 292.3 12.1 1.4 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Piwi PF02171.12 AEO64246.1 - 9.3e-50 169.2 0.0 1.3e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 AEO64246.1 - 3.6e-12 45.4 0.0 7.5e-12 44.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 AEO64246.1 - 5.9e-07 28.8 0.0 1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ESSS PF10183.4 AEO64247.1 - 1.5e-26 92.8 2.5 3e-26 91.8 1.7 1.5 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Aminotran_4 PF01063.14 AEO64248.1 - 1.2e-30 106.7 0.0 1.4e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 AEO64249.1 - 3.4e-16 59.1 0.0 8.6e-16 57.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO64249.1 - 4.5e-07 29.2 0.0 2.2e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase SIR2 PF02146.12 AEO64250.1 - 1.8e-60 203.7 0.0 2.7e-60 203.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 AEO64250.1 - 0.00012 21.6 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 AEO64250.1 - 0.043 13.5 0.1 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain E1-E2_ATPase PF00122.15 AEO64251.1 - 1.5e-57 194.3 1.8 1.5e-57 194.3 1.2 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AEO64251.1 - 3e-42 144.1 4.7 3e-42 144.1 3.3 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AEO64251.1 - 1.3e-30 107.3 0.1 6.1e-30 105.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO64251.1 - 3.8e-20 71.6 0.0 7.6e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AEO64251.1 - 1.3e-18 67.8 0.0 2.3e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AEO64251.1 - 1.3e-07 31.0 3.0 2.4e-07 30.1 0.0 3.0 4 0 0 4 4 4 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AEO64251.1 - 1.6e-06 27.9 0.4 5.8e-06 26.0 0.4 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase YjgP_YjgQ PF03739.9 AEO64251.1 - 0.0041 15.8 3.0 0.0041 15.8 2.1 2.0 2 0 0 2 2 2 1 Predicted permease YjgP/YjgQ family DUF2976 PF11190.3 AEO64251.1 - 0.015 14.7 3.1 1.6 8.3 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF202 PF02656.10 AEO64251.1 - 0.018 15.2 0.6 0.44 10.7 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF202) DevR PF01905.11 AEO64251.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 TTL PF03133.10 AEO64252.1 - 1.5e-53 181.6 0.0 2.5e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 AEO64252.1 - 4.3e-40 137.1 0.0 1.8e-39 135.0 0.0 2.0 1 1 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 AEO64252.1 - 0.00057 19.6 0.0 0.077 12.7 0.0 2.7 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 AEO64252.1 - 0.00087 18.1 0.0 0.0041 15.9 0.0 1.9 2 0 0 2 2 2 1 YheC/D like ATP-grasp KdpA PF03814.10 AEO64252.1 - 0.13 10.2 0.0 0.19 9.7 0.0 1.1 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit Nro1 PF12753.2 AEO64252.1 - 0.16 10.8 0.5 0.27 10.1 0.4 1.4 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 DASH_Duo1 PF08651.5 AEO64254.1 - 4.3e-32 109.5 0.3 6.4e-32 108.9 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF3340 PF11818.3 AEO64254.1 - 0.0047 16.8 0.9 0.0047 16.8 0.6 1.4 2 0 0 2 2 2 1 C-terminal domain of tail specific protease (DUF3340) DUF1682 PF07946.9 AEO64254.1 - 0.093 11.5 5.3 0.13 11.0 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Macoilin PF09726.4 AEO64254.1 - 9.2 4.4 12.7 1 7.5 6.1 1.4 1 1 0 1 1 1 0 Transmembrane protein RNase_H2-Ydr279 PF09468.5 AEO64255.1 - 2.2e-68 230.7 0.4 4.9e-50 170.4 0.0 2.1 1 1 0 2 2 2 2 Ydr279p protein family (RNase H2 complex component) zf-primase PF09329.6 AEO64256.1 - 7e-18 63.9 1.4 1.2e-17 63.2 1.0 1.4 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 AEO64256.1 - 0.017 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain APH PF01636.18 AEO64257.1 - 1.8e-10 40.9 1.5 7.4e-09 35.6 0.1 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO64257.1 - 5.8e-05 22.7 0.0 8.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 AEO64258.1 - 2.6e-17 63.3 0.4 3.6e-17 62.9 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO64258.1 - 0.0039 16.8 0.0 0.013 15.0 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.6 AEO64258.1 - 0.022 13.4 0.0 0.47 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Dna2 PF08696.6 AEO64259.1 - 9.1e-71 237.4 0.0 1.8e-70 236.5 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 AEO64259.1 - 3e-36 124.6 0.0 5.1e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.12 AEO64259.1 - 4.5e-09 36.4 0.1 2.5e-07 30.7 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 AEO64259.1 - 7.5e-09 35.3 0.0 1.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF911 PF06023.7 AEO64259.1 - 0.013 14.7 0.1 0.028 13.6 0.1 1.5 1 1 0 1 1 1 0 Archaeal protein of unknown function (DUF911) COX5B PF01215.14 AEO64259.1 - 0.07 12.7 0.5 7.6 6.2 0.1 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Vb Gryzun PF07919.7 AEO64260.1 - 2.8e-103 346.1 0.0 3.6e-103 345.8 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 AEO64260.1 - 5e-77 258.7 1.2 5e-74 248.9 0.8 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 AEO64260.1 - 0.00024 20.8 0.0 0.00061 19.5 0.0 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking T2SL PF05134.8 AEO64260.1 - 0.38 9.8 7.6 0.13 11.3 0.9 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein L DUF3210 PF11489.3 AEO64261.1 - 2.4e-236 786.8 75.4 2.4e-236 786.8 52.3 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3210) Cg6151-P PF10233.4 AEO64262.1 - 4.4e-39 132.9 15.3 5.3e-39 132.6 10.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P PRA1 PF03208.14 AEO64262.1 - 8.6 5.6 13.3 13 5.1 9.2 1.3 1 0 0 1 1 1 0 PRA1 family protein NTF2 PF02136.15 AEO64263.1 - 3.6e-30 104.7 0.1 4e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 AEO64263.1 - 0.0012 17.9 0.1 0.0023 17.0 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) Mtr2 PF10429.4 AEO64263.1 - 0.094 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Seipin PF06775.9 AEO64265.1 - 2.2e-45 154.6 0.0 2.6e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Imm19 PF15567.1 AEO64265.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 19 FCH PF00611.18 AEO64266.1 - 7.5e-23 80.5 0.1 2.7e-22 78.7 0.1 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 AEO64266.1 - 7.1e-14 50.9 0.0 1.3e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AEO64266.1 - 1.4e-11 43.7 0.0 4.5e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 AEO64266.1 - 1.9e-10 40.1 0.0 3.5e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain UPF0029 PF01205.14 AEO64267.1 - 8.9e-24 83.2 0.0 1.6e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 CHAT PF12770.2 AEO64268.1 - 2.1e-39 135.4 0.2 3.5e-39 134.6 0.2 1.3 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 AEO64268.1 - 2.7e-22 78.4 9.7 0.00021 21.1 0.1 7.2 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 AEO64268.1 - 8.9e-21 73.3 10.8 4.7e-08 32.5 1.8 6.3 3 1 4 7 7 7 5 TPR repeat TPR_2 PF07719.12 AEO64268.1 - 4.6e-08 32.3 14.1 0.81 9.7 0.0 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 AEO64268.1 - 7.2e-06 26.1 29.1 0.31 11.7 0.9 8.7 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 AEO64268.1 - 0.0049 17.5 21.0 0.063 13.9 1.7 6.1 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.1 AEO64268.1 - 0.022 14.6 0.3 0.022 14.6 0.2 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_19 PF14559.1 AEO64268.1 - 0.031 14.6 16.0 1.6 9.1 0.1 6.0 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO64268.1 - 0.055 13.1 21.4 1.2 8.9 0.1 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_15 PF13429.1 AEO64268.1 - 0.061 12.3 8.7 0.21 10.6 0.4 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF892 PF05974.7 AEO64268.1 - 0.07 12.9 0.4 0.37 10.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF892) DUF4404 PF14357.1 AEO64268.1 - 0.081 13.3 2.7 8 6.9 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) TPR_7 PF13176.1 AEO64268.1 - 2.4 8.1 8.6 9.6 6.2 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat Methyltransf_23 PF13489.1 AEO64269.1 - 4.9e-11 42.6 0.0 5.4e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO64269.1 - 0.002 18.5 0.0 2 8.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 AEO64269.1 - 0.0032 17.9 0.0 0.15 12.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO64269.1 - 0.022 15.3 0.0 0.079 13.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Gag_p15 PF08723.5 AEO64269.1 - 0.035 14.0 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 Gag protein p15 Not1 PF04054.10 AEO64271.1 - 2.1e-112 375.7 0.0 6.7e-112 374.0 0.0 1.9 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 AEO64271.1 - 1e-47 161.5 0.6 2.9e-47 160.0 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CorA PF01544.13 AEO64272.1 - 2.9e-12 46.2 7.4 1.1e-11 44.3 0.4 2.3 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein ETF_QO PF05187.8 AEO64273.1 - 1.5e-44 150.4 0.0 2.7e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 AEO64273.1 - 3.4e-08 32.7 0.7 0.00021 20.3 0.1 2.8 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO64273.1 - 2.1e-07 30.8 0.0 7.2e-07 29.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 AEO64273.1 - 2.9e-05 23.2 0.0 0.0059 15.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 AEO64273.1 - 7.3e-05 22.7 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO64273.1 - 7.5e-05 21.9 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AEO64273.1 - 9.7e-05 20.9 0.3 0.00014 20.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 AEO64273.1 - 0.00022 20.2 0.2 0.0021 16.9 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 AEO64273.1 - 0.001 18.8 0.2 0.0044 16.8 0.1 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 AEO64273.1 - 0.0011 18.1 0.1 0.0021 17.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.2 AEO64273.1 - 0.0024 18.2 1.1 0.0075 16.6 0.8 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox_3 PF13738.1 AEO64273.1 - 0.0026 17.8 0.0 0.0057 16.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 AEO64273.1 - 0.0029 16.2 0.0 0.29 9.7 0.0 2.2 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 AEO64273.1 - 0.012 15.9 0.2 5 7.5 0.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO64273.1 - 0.016 14.1 0.2 0.026 13.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 AEO64273.1 - 0.072 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_10 PF13237.1 AEO64273.1 - 0.11 12.3 0.9 0.31 10.8 0.7 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain RTA1 PF04479.8 AEO64274.1 - 4.5e-39 134.2 5.7 6.5e-39 133.7 4.0 1.1 1 0 0 1 1 1 1 RTA1 like protein NB PF04159.8 AEO64274.1 - 0.018 14.7 1.0 0.028 14.1 0.1 1.8 2 0 0 2 2 2 0 NB glycoprotein DUF485 PF04341.7 AEO64274.1 - 0.025 14.2 0.8 0.025 14.2 0.5 3.2 3 1 1 4 4 4 0 Protein of unknown function, DUF485 Exonuc_V_gamma PF04257.9 AEO64275.1 - 0.019 13.0 0.3 0.02 12.9 0.2 1.0 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit RVT_1 PF00078.22 AEO64275.1 - 0.088 12.1 0.6 0.1 11.9 0.4 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Plasmodium_Vir PF05795.6 AEO64275.1 - 0.16 11.1 2.1 0.21 10.7 1.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Zn_clus PF00172.13 AEO64276.1 - 0.00044 20.0 11.6 0.00096 19.0 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SURF2 PF05477.6 AEO64276.1 - 0.066 12.3 0.0 0.36 9.9 0.0 2.0 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) MFS_1 PF07690.11 AEO64277.1 - 9e-30 103.5 93.5 2.5e-28 98.8 43.1 3.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO64277.1 - 1.1e-09 37.4 10.7 1.1e-09 37.4 7.4 3.2 1 1 0 3 3 3 2 Sugar (and other) transporter TBP PF00352.16 AEO64279.1 - 2.3e-70 231.9 0.2 3.3e-35 119.2 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 AEO64279.1 - 0.00021 21.2 0.0 0.77 9.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 AEO64279.1 - 0.014 15.7 0.4 0.02 15.2 0.3 1.3 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) DAO PF01266.19 AEO64280.1 - 5.8e-51 173.4 0.6 8.8e-51 172.8 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 AEO64280.1 - 1.1e-08 34.9 0.4 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 AEO64280.1 - 5.5e-06 25.4 0.1 3.8e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 AEO64280.1 - 3.6e-05 22.5 0.1 0.022 13.4 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 AEO64280.1 - 8.5e-05 22.5 0.0 0.097 12.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO64280.1 - 0.00016 21.6 0.0 0.0012 18.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 AEO64280.1 - 0.0072 16.7 0.0 0.024 15.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO64280.1 - 0.0074 15.2 0.1 0.28 10.0 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 AEO64280.1 - 0.0077 15.3 0.2 0.26 10.3 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.19 AEO64280.1 - 0.014 14.2 4.9 0.66 8.7 3.4 2.2 1 1 0 1 1 1 0 FAD binding domain Saccharop_dh PF03435.13 AEO64280.1 - 0.022 13.7 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DivIC PF04977.10 AEO64280.1 - 0.026 13.9 0.0 5.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Septum formation initiator Surp PF01805.15 AEO64281.1 - 3e-17 62.0 0.0 8.3e-17 60.5 0.0 1.8 1 0 0 1 1 1 1 Surp module RRM_6 PF14259.1 AEO64281.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Methyltransf_16 PF10294.4 AEO64284.1 - 7.5e-08 32.0 0.0 7.7e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 AEO64284.1 - 3.3e-05 24.4 0.0 0.0002 21.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 AEO64284.1 - 0.0021 17.2 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.10 AEO64284.1 - 0.027 13.5 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MTS PF05175.9 AEO64284.1 - 0.031 13.6 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DUF2730 PF10805.3 AEO64286.1 - 0.12 12.0 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) EMP70 PF02990.11 AEO64286.1 - 0.56 8.5 6.4 0.082 11.3 1.4 1.7 2 0 0 2 2 2 0 Endomembrane protein 70 SNF2_N PF00176.18 AEO64287.1 - 1.4e-76 257.1 0.3 2e-69 233.6 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO64287.1 - 7.8e-09 35.2 0.0 1.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD_2 PF06733.10 AEO64287.1 - 0.05 13.0 0.3 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 DEAD_2 MFS_1 PF07690.11 AEO64289.1 - 2.4e-29 102.1 43.6 4.9e-29 101.1 29.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 AEO64289.1 - 0.0026 17.1 6.2 0.61 9.6 0.0 4.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1049) COX6C PF02937.10 AEO64289.1 - 0.043 13.7 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc Ran-binding PF05508.6 AEO64290.1 - 1.3e-105 352.6 0.0 1.6e-105 352.3 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein ING PF12998.2 AEO64290.1 - 0.022 15.0 0.1 0.052 13.8 0.1 1.6 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Nop14 PF04147.7 AEO64290.1 - 1.3 6.8 6.1 1.8 6.3 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family GTP_EFTU PF00009.22 AEO64291.1 - 9.1e-44 149.1 0.0 1.7e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AEO64291.1 - 2e-20 72.7 0.4 5.2e-20 71.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AEO64291.1 - 1.5e-06 28.1 0.1 4.7e-06 26.6 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AEO64291.1 - 0.00011 22.1 0.0 0.00032 20.6 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 AEO64291.1 - 0.13 11.8 0.0 0.58 9.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mitofilin PF09731.4 AEO64291.1 - 4 5.9 18.7 5.8 5.4 13.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein adh_short PF00106.20 AEO64292.1 - 3.1e-21 75.9 4.4 3e-20 72.8 3.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO64292.1 - 1.8e-15 57.4 0.0 6.7e-15 55.5 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO64292.1 - 5.7e-09 35.8 0.5 5.7e-09 35.8 0.3 1.6 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 AEO64292.1 - 0.034 14.2 0.1 0.052 13.6 0.1 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Phosphoprotein PF00922.12 AEO64293.1 - 1.4 8.0 5.5 1.7 7.7 3.8 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Mito_carr PF00153.22 AEO64294.1 - 8.7e-54 179.2 4.7 5.8e-18 64.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SecE PF00584.15 AEO64294.1 - 0.004 16.6 0.1 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex UCH_1 PF13423.1 AEO64295.1 - 1.2e-54 185.8 0.0 1.7e-54 185.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 AEO64295.1 - 1.3e-26 93.8 0.0 2.4e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 AEO64295.1 - 2.4e-06 26.8 0.0 5.1e-05 22.5 0.0 2.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4242 PF14026.1 AEO64296.1 - 0.098 12.7 0.8 0.41 10.7 0.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) RHINO PF15319.1 AEO64296.1 - 0.9 9.2 5.5 0.23 11.2 1.2 1.8 1 1 0 2 2 2 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein 5_3_exonuc PF01367.15 AEO64296.1 - 9.9 6.4 10.5 1.9 8.7 0.9 3.2 1 1 2 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold HET PF06985.6 AEO64297.1 - 2.4e-29 102.2 0.0 9.1e-29 100.3 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nup96 PF12110.3 AEO64298.1 - 1.7e-63 214.4 0.0 2.5e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 AEO64298.1 - 5.7e-43 146.1 0.0 8.8e-43 145.4 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 AEO64298.1 - 9.9e-20 70.8 317.0 1.9e-09 37.7 28.6 10.8 4 2 7 11 11 11 6 Nucleoporin FG repeat region HNH_2 PF13391.1 AEO64299.1 - 1.6e-18 66.2 0.0 2.7e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease ENTH PF01417.15 AEO64300.1 - 2.8e-50 169.3 0.1 4.4e-50 168.7 0.1 1.3 1 0 0 1 1 1 1 ENTH domain DUF4264 PF14084.1 AEO64300.1 - 0.0088 15.3 0.1 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) UIM PF02809.15 AEO64300.1 - 0.052 13.1 6.3 0.043 13.3 0.8 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif VHS PF00790.14 AEO64300.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 VHS domain DUF1510 PF07423.6 AEO64300.1 - 8.8 5.6 18.1 1.8 7.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) MOZ_SAS PF01853.13 AEO64301.1 - 2.2e-80 268.3 0.1 3.1e-80 267.8 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family ATP_bind_3 PF01171.15 AEO64303.1 - 3.6e-18 65.6 0.0 6.3e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 AEO64303.1 - 0.00046 20.4 0.0 0.00084 19.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) RecR PF02132.10 AEO64303.1 - 0.00047 19.5 0.9 0.00047 19.5 0.7 2.9 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.11 AEO64303.1 - 0.0031 16.1 0.0 0.0049 15.4 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase zf-UBR PF02207.15 AEO64303.1 - 0.13 11.9 5.8 0.54 10.0 0.2 2.8 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) ThiI PF02568.9 AEO64303.1 - 0.14 11.5 0.0 0.61 9.5 0.0 1.9 1 1 1 2 2 2 0 Thiamine biosynthesis protein (ThiI) DUF3970 PF13113.1 AEO64303.1 - 0.2 11.3 1.0 0.46 10.2 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) DZR PF12773.2 AEO64303.1 - 3.8 7.3 10.0 8.5 6.2 0.4 3.3 3 0 0 3 3 3 0 Double zinc ribbon Ribosomal_L7Ae PF01248.21 AEO64304.1 - 2.2e-22 78.3 0.9 3.9e-22 77.5 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pro_CA PF00484.14 AEO64305.1 - 7e-46 155.9 1.0 8.3e-46 155.7 0.7 1.1 1 0 0 1 1 1 1 Carbonic anhydrase OCD_Mu_crystall PF02423.10 AEO64306.1 - 5e-07 28.7 6.8 0.01 14.6 2.5 3.2 3 1 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family MOZART1 PF12554.3 AEO64306.1 - 0.052 13.0 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated TRAUB PF08164.7 AEO64307.1 - 1.9e-31 108.0 1.0 6.4e-31 106.3 0.0 2.4 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 AEO64307.1 - 4.8e-31 107.6 2.3 4.8e-31 107.6 1.6 2.9 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor ParA PF10609.4 AEO64308.1 - 1.2e-30 105.2 0.1 2.2e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 AEO64308.1 - 3.8e-15 55.7 0.0 5.4e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 AEO64308.1 - 3.7e-07 30.1 0.0 1.8e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 AEO64308.1 - 2.6e-05 23.4 0.0 5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.13 AEO64308.1 - 0.00021 20.5 0.0 0.2 10.8 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.1 AEO64308.1 - 0.00028 20.5 0.1 0.052 13.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.10 AEO64308.1 - 0.0008 18.5 0.2 0.0015 17.6 0.0 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 AEO64308.1 - 0.011 15.2 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain YhjQ PF06564.7 AEO64308.1 - 0.033 13.5 0.7 0.058 12.7 0.2 1.5 2 0 0 2 2 2 0 YhjQ protein ArgK PF03308.11 AEO64308.1 - 0.072 11.8 0.8 0.1 11.3 0.0 1.5 2 0 0 2 2 2 0 ArgK protein DUF4537 PF15057.1 AEO64309.1 - 0.0094 15.7 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF2360 PF10152.4 AEO64309.1 - 3.5 7.9 14.0 2.9 8.1 3.0 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) TCO89 PF10452.4 AEO64310.1 - 0.024 13.5 17.1 0.053 12.4 0.1 3.2 3 0 0 3 3 3 0 TORC1 subunit TCO89 Thiolase_N PF00108.18 AEO64311.1 - 2e-79 266.3 4.3 2.9e-79 265.7 3.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AEO64311.1 - 1.6e-44 150.2 0.2 4.8e-44 148.7 0.0 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 AEO64311.1 - 0.0069 16.3 0.0 0.023 14.6 0.0 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FBPase PF00316.15 AEO64312.1 - 1.3e-123 411.9 0.0 1.5e-123 411.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase F-box-like PF12937.2 AEO64313.1 - 1e-05 25.1 0.7 1e-05 25.1 0.5 2.9 4 0 0 4 4 4 1 F-box-like F-box PF00646.28 AEO64313.1 - 0.0023 17.5 2.0 0.0023 17.5 1.4 2.5 3 0 0 3 3 3 1 F-box domain p450 PF00067.17 AEO64314.1 - 2.8e-45 154.6 0.0 1.6e-41 142.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Sugar_tr PF00083.19 AEO64315.1 - 6.5e-33 113.9 33.5 5.1e-21 74.7 8.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 AEO64315.1 - 5.7e-19 68.0 50.1 5.1e-15 55.0 15.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Chal_sti_synt_N PF00195.14 AEO64316.1 - 1.6e-19 70.0 0.1 2.6e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 AEO64316.1 - 8.1e-19 68.0 0.0 1.3e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.7 AEO64316.1 - 5.7e-06 25.6 0.0 8e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.5 AEO64316.1 - 0.00013 21.5 0.0 0.00034 20.1 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 AEO64316.1 - 0.00055 19.8 0.0 0.0021 18.0 0.0 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal PEX11 PF05648.9 AEO64317.1 - 7.6e-69 231.3 0.2 8.5e-69 231.2 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) NMO PF03060.10 AEO64318.1 - 1.6e-63 214.8 0.0 2.2e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 AEO64318.1 - 4.6e-11 42.2 0.0 1.2e-05 24.3 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 AEO64318.1 - 0.0082 15.0 0.1 0.014 14.2 0.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.9 AEO64318.1 - 0.053 12.4 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DND1_DSRM PF14709.1 AEO64319.1 - 0.032 14.5 0.0 0.18 12.0 0.0 2.3 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Ribosomal_S7 PF00177.16 AEO64321.1 - 6.3e-24 84.2 0.0 8.7e-24 83.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Usp PF00582.21 AEO64322.1 - 2.5e-23 82.8 0.8 1.1e-14 54.8 0.1 2.9 2 0 0 2 2 2 2 Universal stress protein family Baculo_PEP_C PF04513.7 AEO64323.1 - 1.3 8.8 5.3 1.3 8.8 0.3 3.3 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus RRM_1 PF00076.17 AEO64324.1 - 1.6e-85 280.7 5.0 7.6e-24 83.1 0.3 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO64324.1 - 4.3e-55 183.5 0.7 1.4e-15 56.9 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO64324.1 - 1.1e-41 140.5 0.2 3.2e-10 39.7 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 AEO64324.1 - 9.3e-29 98.9 2.8 5.6e-28 96.4 1.9 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 AEO64324.1 - 9.7e-06 25.2 1.4 6.3 6.6 0.1 4.9 4 1 0 4 4 4 2 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 AEO64324.1 - 0.00039 20.5 0.6 5.3 7.3 0.0 4.0 4 0 0 4 4 4 1 Cobalamin biosynthesis central region YflT PF11181.3 AEO64324.1 - 0.029 14.5 4.8 0.48 10.5 0.2 3.3 3 0 0 3 3 3 0 Heat induced stress protein YflT OB_RNB PF08206.6 AEO64324.1 - 0.069 12.6 2.2 7.6 6.1 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain HECT PF00632.20 AEO64325.1 - 4e-84 282.4 0.0 5.5e-84 282.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 AEO64325.1 - 0.0018 17.7 3.9 0.0058 16.1 2.7 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif Glyco_hydro_92 PF07971.7 AEO64326.1 - 1.2e-168 561.9 0.0 1.4e-168 561.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 PTPA PF03095.10 AEO64327.1 - 8e-34 117.1 0.0 9.9e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Rad4 PF03835.10 AEO64328.1 - 2.2e-28 98.4 0.0 5.5e-28 97.1 0.0 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 AEO64328.1 - 7.7e-26 89.6 0.1 1.3e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 AEO64328.1 - 5e-20 70.7 0.0 1e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 AEO64328.1 - 1.1e-11 44.8 0.0 3.7e-11 43.1 0.0 2.0 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 AEO64328.1 - 0.00025 21.2 0.0 0.0013 18.9 0.0 2.2 1 1 0 1 1 1 1 Transglutaminase-like superfamily SET PF00856.23 AEO64328.1 - 0.0079 16.5 0.0 0.57 10.4 0.0 3.3 3 1 0 3 3 3 1 SET domain DUF3439 PF11921.3 AEO64328.1 - 1.1 9.0 5.0 2.6 7.8 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) COX15-CtaA PF02628.10 AEO64329.1 - 2.1e-96 322.3 8.6 2.6e-96 322.0 6.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF3285 PF11688.3 AEO64329.1 - 0.062 12.9 1.7 0.31 10.6 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3285) Zip PF02535.17 AEO64330.1 - 1.8e-47 161.8 0.0 3.2e-47 161.0 0.0 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Pkinase PF00069.20 AEO64331.1 - 0.0026 16.9 0.0 0.018 14.1 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain ODC_AZ PF02100.12 AEO64331.1 - 0.036 13.5 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Ornithine decarboxylase antizyme OrfB_Zn_ribbon PF07282.6 AEO64331.1 - 0.32 10.6 2.4 0.9 9.2 1.2 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Robl_LC7 PF03259.12 AEO64332.1 - 0.019 14.5 0.4 0.019 14.5 0.3 1.8 2 0 0 2 2 2 0 Roadblock/LC7 domain LEA_3 PF03242.8 AEO64332.1 - 1.2 9.3 4.2 0.73 10.1 0.1 2.3 2 1 1 3 3 3 0 Late embryogenesis abundant protein 2-Hacid_dh_C PF02826.14 AEO64333.1 - 3e-53 179.6 0.0 4.5e-53 179.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AEO64333.1 - 5.1e-33 113.3 0.1 9.3e-33 112.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 AEO64333.1 - 2.7e-05 24.0 0.1 5.2e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.1 AEO64333.1 - 0.0088 16.3 0.0 0.026 14.8 0.0 1.9 1 0 0 1 1 1 1 XdhC Rossmann domain AlaDh_PNT_C PF01262.16 AEO64333.1 - 3 7.4 6.2 0.61 9.6 1.6 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Glyoxalase PF00903.20 AEO64334.1 - 3e-40 137.1 0.0 1.3e-20 73.6 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 AEO64334.1 - 1.2e-32 112.7 0.0 6.9e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 AEO64334.1 - 1.7e-18 66.6 0.0 1.3e-08 34.7 0.0 3.8 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 AEO64334.1 - 2.3e-05 24.3 0.0 0.15 11.9 0.0 3.0 3 1 1 4 4 4 2 Glyoxalase-like domain DUF4105 PF13387.1 AEO64334.1 - 0.049 12.8 0.0 12 5.0 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4105) PRT_C PF08372.5 AEO64334.1 - 0.11 12.0 0.0 6.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal DUF21 PF01595.15 AEO64335.1 - 5.9e-32 110.4 0.0 1e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 AEO64335.1 - 0.00037 20.2 0.2 0.019 14.7 0.0 2.6 2 0 0 2 2 2 1 CBS domain Filament PF00038.16 AEO64337.1 - 0.0018 17.8 164.5 0.041 13.3 25.6 7.2 1 1 4 6 6 6 4 Intermediate filament protein TMF_DNA_bd PF12329.3 AEO64337.1 - 0.0027 17.4 6.4 0.0027 17.4 4.4 17.0 4 3 10 16 16 16 5 TATA element modulatory factor 1 DNA binding Bap31 PF05529.7 AEO64337.1 - 0.0059 16.0 0.3 0.0059 16.0 0.2 12.3 3 2 5 8 8 8 1 B-cell receptor-associated protein 31-like Zn_clus PF00172.13 AEO64339.1 - 2.7e-07 30.3 11.3 4.1e-07 29.8 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO64339.1 - 5.1e-06 25.5 0.0 9.1e-06 24.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ApbA PF02558.11 AEO64342.1 - 6.6e-32 110.0 0.0 9.5e-32 109.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 AEO64342.1 - 7.1e-23 80.9 0.0 1.2e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pyr_redox PF00070.22 AEO64342.1 - 0.066 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FRQ PF09421.5 AEO64344.1 - 0.0015 16.4 0.7 0.0019 16.0 0.5 1.2 1 0 0 1 1 1 1 Frequency clock protein DUF2461 PF09365.5 AEO64345.1 - 6e-68 228.4 0.0 7.5e-68 228.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) PhyH PF05721.8 AEO64346.1 - 7.6e-12 45.7 0.0 8.3e-11 42.3 0.0 2.2 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.11 AEO64346.1 - 0.013 15.1 0.0 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family Pectate_lyase_3 PF12708.2 AEO64347.1 - 1.7e-89 299.8 20.3 8.5e-70 235.3 5.7 3.0 2 1 1 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 AEO64347.1 - 1.6e-07 30.6 1.5 0.0064 15.9 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Fungal_trans PF04082.13 AEO64348.1 - 1.2e-15 57.1 1.6 1.2e-15 57.1 1.1 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 AEO64348.1 - 2.4e-07 30.6 11.6 0.0026 17.9 2.4 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO64348.1 - 1.1e-06 28.6 11.9 3.4e-05 23.9 0.9 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO64348.1 - 6e-06 26.2 14.2 0.0011 19.0 2.6 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO64348.1 - 0.045 13.9 0.7 0.61 10.3 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Gly_kinase PF02595.10 AEO64348.1 - 0.098 11.3 0.0 0.49 9.0 0.0 1.8 2 0 0 2 2 2 0 Glycerate kinase family PyrI_C PF02748.10 AEO64348.1 - 0.22 10.9 0.1 0.41 10.1 0.0 1.4 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain VHS PF00790.14 AEO64349.1 - 1.7e-37 128.1 0.1 4e-37 126.9 0.1 1.6 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 AEO64349.1 - 2.4e-16 59.0 0.2 4.7e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AEO64349.1 - 4.3e-16 58.0 0.0 8.6e-16 57.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AEO64349.1 - 2.6e-14 52.4 0.1 4.9e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 AEO64349.1 - 0.034 14.0 1.4 0.12 12.3 1.0 1.9 1 0 0 1 1 1 0 GAT domain UIM PF02809.15 AEO64349.1 - 0.16 11.6 5.6 0.37 10.4 3.9 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif TIR PF01582.15 AEO64349.1 - 0.19 11.1 0.4 0.44 9.9 0.3 1.5 1 0 0 1 1 1 0 TIR domain HEAT_2 PF13646.1 AEO64349.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.2 3 0 0 3 3 3 0 HEAT repeats DUF4220 PF13968.1 AEO64349.1 - 0.58 9.1 1.2 1.7 7.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) DUF445 PF04286.7 AEO64349.1 - 5.3 6.4 6.8 0.26 10.7 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Phage_holin PF04688.8 AEO64350.1 - 0.0039 16.6 1.8 0.0074 15.7 1.2 1.4 1 0 0 1 1 1 1 Phage lysis protein, holin p450 PF00067.17 AEO64353.1 - 5.6e-42 143.8 0.0 6.9e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_2b PF00587.20 AEO64354.1 - 4.2e-42 143.6 0.0 7.3e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AEO64354.1 - 3.6e-21 74.9 0.0 1e-20 73.4 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain ATG13 PF10033.4 AEO64355.1 - 1.4e-70 237.3 0.0 2.3e-70 236.6 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 RCC1 PF00415.13 AEO64356.1 - 2.1e-22 79.0 0.4 1.7e-06 28.1 0.1 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 AEO64356.1 - 9.7e-12 44.8 0.0 1.5e-07 31.4 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 AEO64356.1 - 6.7e-10 39.2 0.2 2.3e-09 37.5 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (many copies) RCC1_2 PF13540.1 AEO64356.1 - 5e-08 32.3 6.1 7.3e-07 28.6 0.9 3.7 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 AEO64356.1 - 2.6e-06 27.1 0.4 0.041 14.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 AEO64356.1 - 0.00015 21.9 0.1 0.00051 20.3 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 AEO64356.1 - 0.012 15.4 0.2 0.061 13.1 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.1 AEO64356.1 - 0.037 14.2 0.2 0.25 11.6 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (many copies) RTA1 PF04479.8 AEO64358.1 - 2.9e-33 115.2 1.4 4.3e-33 114.6 1.0 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF2244 PF10003.4 AEO64358.1 - 1.1 8.6 11.1 0.039 13.3 1.3 2.7 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) Mito_carr PF00153.22 AEO64359.1 - 3.4e-68 225.4 3.0 1.4e-24 85.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Nop14 PF04147.7 AEO64360.1 - 0.46 8.3 46.4 0.071 11.0 17.6 2.2 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.5 AEO64361.1 - 1e-70 239.0 57.4 2.3e-68 231.2 39.8 2.7 1 1 0 1 1 1 1 BUD22 EF-hand_1 PF00036.27 AEO64362.1 - 2.7e-21 73.1 6.4 1.3e-07 30.4 0.1 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 AEO64362.1 - 5.5e-20 71.2 1.0 4.9e-12 45.8 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 AEO64362.1 - 1.2e-19 69.6 3.5 9e-10 38.0 0.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 AEO64362.1 - 2e-19 67.6 6.6 1.4e-07 30.7 0.3 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 AEO64362.1 - 7.2e-13 47.2 9.6 2.2e-05 23.5 0.4 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 AEO64362.1 - 3e-05 23.8 0.0 0.00084 19.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain Caleosin PF05042.8 AEO64362.1 - 0.0089 15.5 0.0 0.41 10.1 0.0 2.0 2 0 0 2 2 2 1 Caleosin related protein EFhand_Ca_insen PF08726.5 AEO64362.1 - 0.025 14.5 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 Ca2+ insensitive EF hand EF-hand_4 PF12763.2 AEO64362.1 - 0.058 13.1 0.1 0.6 9.8 0.0 2.2 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Polysacc_synt_3 PF13440.1 AEO64363.1 - 0.041 13.3 3.4 0.063 12.7 2.3 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein p450 PF00067.17 AEO64364.1 - 7.2e-47 159.9 0.0 1.1e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PEPCK_ATP PF01293.15 AEO64365.1 - 9e-217 720.1 0.0 1.1e-216 719.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 AEO64365.1 - 0.035 14.3 0.1 6.1 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 AEO64365.1 - 0.084 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 AEO64365.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AEO64365.1 - 0.18 11.3 0.5 0.44 10.1 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cupin_8 PF13621.1 AEO64366.1 - 7.2e-21 74.8 0.0 8.8e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 AEO64366.1 - 0.002 18.3 0.0 0.0051 17.0 0.0 1.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase CK_II_beta PF01214.13 AEO64367.1 - 3.4e-77 258.1 0.0 5.7e-77 257.3 0.0 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 AEO64367.1 - 0.017 15.7 12.2 0.069 13.7 3.8 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Sporozoite_P67 PF05642.6 AEO64367.1 - 0.3 8.8 2.9 0.24 9.2 0.1 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Myc_N PF01056.13 AEO64367.1 - 0.89 8.6 5.8 0.34 10.0 1.4 2.0 2 0 0 2 2 2 0 Myc amino-terminal region LZ_Tnp_IS66 PF13007.2 AEO64367.1 - 0.95 10.1 8.9 0.46 11.1 0.2 2.5 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain FAM176 PF14851.1 AEO64367.1 - 1.1 8.9 6.7 0.33 10.6 1.0 2.1 2 0 0 2 2 2 0 FAM176 family RRN3 PF05327.6 AEO64367.1 - 6.9 4.6 5.8 0.46 8.5 0.5 1.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Nucleoplasmin PF03066.10 AEO64367.1 - 7.3 6.1 14.6 0.98 8.9 4.5 2.1 2 0 0 2 2 2 0 Nucleoplasmin ABC2_membrane PF01061.19 AEO64368.1 - 4e-80 267.9 53.7 5.6e-41 140.0 13.0 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 AEO64368.1 - 2.1e-35 122.0 0.0 3.8e-17 62.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 AEO64368.1 - 1.5e-27 95.2 3.8 2.5e-24 84.9 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 AEO64368.1 - 7.5e-09 35.5 0.0 2.7e-08 33.7 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 AEO64368.1 - 5.5e-06 26.3 2.4 0.0023 17.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain cobW PF02492.14 AEO64368.1 - 7.5e-06 25.4 0.9 0.0037 16.7 0.4 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 AEO64368.1 - 7.6e-06 26.7 0.0 0.017 15.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AEO64368.1 - 8.6e-06 25.2 0.2 0.0042 16.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 AEO64368.1 - 1.3e-05 25.2 0.0 0.053 13.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 AEO64368.1 - 2.2e-05 24.5 0.0 0.23 11.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain ABC2_membrane_3 PF12698.2 AEO64368.1 - 3.8e-05 22.8 37.3 0.004 16.2 7.1 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 AEO64368.1 - 7.2e-05 22.8 0.1 0.014 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 AEO64368.1 - 0.0001 21.7 0.3 0.0048 16.4 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain UPF0079 PF02367.12 AEO64368.1 - 0.0003 20.3 0.9 0.6 9.7 0.1 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 AEO64368.1 - 0.00034 20.6 3.0 0.03 14.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 AEO64368.1 - 0.00066 19.3 0.5 0.63 9.8 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain DUF258 PF03193.11 AEO64368.1 - 0.002 17.3 0.0 0.0094 15.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 AEO64368.1 - 0.0036 16.9 0.5 2 8.0 0.0 2.5 2 0 0 2 2 2 2 NACHT domain SMC_N PF02463.14 AEO64368.1 - 0.007 15.6 0.0 0.71 9.0 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 AEO64368.1 - 0.0091 16.2 3.3 0.31 11.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.13 AEO64368.1 - 0.02 14.3 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 AEO64368.1 - 0.04 14.4 0.0 7.6 7.0 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 AEO64368.1 - 0.046 13.1 0.4 2.7 7.3 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain PduV-EutP PF10662.4 AEO64368.1 - 0.064 12.7 1.0 2.2 7.7 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 AEO64368.1 - 0.08 13.1 0.2 14 5.9 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 AEO64368.1 - 0.15 12.3 0.5 0.58 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 AEO64368.1 - 0.15 11.6 0.1 13 5.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 AEO64368.1 - 0.17 11.3 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.1 AEO64368.1 - 0.65 8.9 0.0 4 6.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain RRM_6 PF14259.1 AEO64369.1 - 4.8e-09 36.0 0.0 1.2e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO64369.1 - 7.4e-08 31.9 0.0 1.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NPBW PF15180.1 AEO64369.1 - 0.072 12.7 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Neuropeptides B and W Leu_zip PF15294.1 AEO64371.1 - 0.00062 18.9 0.3 0.00095 18.3 0.2 1.2 1 0 0 1 1 1 1 Leucine zipper Zip PF02535.17 AEO64371.1 - 0.013 14.4 11.7 0.28 10.1 1.3 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter PV-1 PF06637.6 AEO64371.1 - 0.019 13.5 1.9 0.039 12.5 1.3 1.4 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Striatin PF08232.7 AEO64371.1 - 0.46 10.7 7.6 1.1 9.5 1.7 2.3 2 0 0 2 2 2 0 Striatin family SPX PF03105.14 AEO64371.1 - 9.3 5.9 8.0 29 4.3 2.7 2.4 1 1 0 2 2 2 0 SPX domain Zn_clus PF00172.13 AEO64372.1 - 0.36 10.7 11.3 0.63 9.9 7.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP1 PF07218.6 AEO64372.1 - 2.5 6.0 3.7 3.4 5.6 2.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) adh_short PF00106.20 AEO64373.1 - 2.9e-25 89.0 1.7 3.8e-25 88.7 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO64373.1 - 1e-21 77.8 0.0 1.2e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO64373.1 - 3.7e-09 36.4 0.7 5.3e-09 35.9 0.5 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 AEO64373.1 - 2e-06 27.2 0.1 3e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO64373.1 - 0.00034 20.6 0.1 0.00052 20.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 AEO64373.1 - 0.008 15.3 0.0 0.37 9.8 0.0 2.1 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 AEO64373.1 - 0.062 12.7 0.1 0.12 11.7 0.0 1.6 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 AEO64373.1 - 0.1 11.4 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.10 AEO64373.1 - 0.11 12.1 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PQQ_3 PF13570.1 AEO64375.1 - 0.018 15.3 0.1 0.1 12.9 0.0 2.4 1 0 0 1 1 1 0 PQQ-like domain WD40 PF00400.27 AEO64375.1 - 3.1 7.8 6.8 8.9 6.3 0.0 4.1 5 0 0 5 5 5 0 WD domain, G-beta repeat HgmA PF04209.8 AEO64378.1 - 3.3e-173 575.9 0.0 3.9e-173 575.7 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Methyltransf_23 PF13489.1 AEO64379.1 - 1.6e-24 86.4 0.0 2.5e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO64379.1 - 3.5e-14 52.6 0.0 1.4e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO64379.1 - 1e-12 48.3 0.0 5.1e-12 46.1 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO64379.1 - 2e-12 47.4 0.0 5.1e-12 46.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO64379.1 - 2e-12 47.6 0.0 1.9e-11 44.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO64379.1 - 1e-07 32.2 0.0 2.9e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 AEO64379.1 - 6.5e-06 25.6 0.0 3e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 AEO64379.1 - 0.00058 19.1 0.0 0.00081 18.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_26 PF13659.1 AEO64379.1 - 0.00066 19.6 0.0 0.0025 17.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO64379.1 - 0.00067 18.8 0.0 0.0035 16.5 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 AEO64379.1 - 0.0009 18.4 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 AEO64379.1 - 0.001 19.1 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.7 AEO64379.1 - 0.025 13.9 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 AEO64379.1 - 0.032 13.2 0.0 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.4 AEO64379.1 - 0.066 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DAO PF01266.19 AEO64380.1 - 8.5e-59 199.2 5.2 1.1e-58 198.9 3.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AEO64380.1 - 2.1e-05 24.6 0.4 0.0028 17.7 0.3 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO64380.1 - 0.0011 18.8 0.3 0.0038 17.2 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 AEO64380.1 - 0.0013 18.4 0.3 0.0059 16.3 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding DUF3716 PF12511.3 AEO64381.1 - 6.3e-05 22.5 4.9 0.00011 21.7 3.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) TFIIF_alpha PF05793.7 AEO64381.1 - 0.038 12.3 8.6 0.048 12.0 6.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Methyltransf_16 PF10294.4 AEO64385.1 - 9.4e-27 93.5 0.0 2.4e-26 92.2 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 AEO64385.1 - 5.7e-05 23.6 0.0 9.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO64385.1 - 0.0034 17.1 0.0 0.0058 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO64385.1 - 0.0066 15.8 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 AEO64385.1 - 0.045 14.2 0.0 0.09 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 AEO64385.1 - 0.24 10.9 0.1 0.36 10.4 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase domain RCC1 PF00415.13 AEO64387.1 - 2.3e-58 194.1 6.9 5.4e-09 36.1 0.0 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AEO64387.1 - 5.8e-37 124.5 19.9 4e-07 29.4 0.2 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 AEO64387.1 - 0.0067 15.8 1.2 1.1 8.8 0.0 2.7 2 0 0 2 2 2 2 Putative carbohydrate binding domain Yip1 PF04893.12 AEO64388.1 - 0.00014 21.4 19.1 0.0076 15.7 6.7 2.6 2 1 1 3 3 3 2 Yip1 domain Pam16 PF03656.8 AEO64389.1 - 3.8e-34 117.2 0.2 4.6e-34 116.9 0.2 1.0 1 0 0 1 1 1 1 Pam16 BPL_N PF09825.4 AEO64392.1 - 2.7e-143 477.2 0.0 3.2e-143 476.9 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 AEO64392.1 - 1.3e-20 73.7 0.0 5.6e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family DUF2757 PF10955.3 AEO64392.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) Mgm101p PF06420.7 AEO64393.1 - 3.8e-90 299.7 0.0 4.8e-90 299.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 TB2_DP1_HVA22 PF03134.14 AEO64394.1 - 5e-31 106.2 7.8 7.6e-31 105.7 5.4 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family ALMS_motif PF15309.1 AEO64394.1 - 0.029 14.2 0.7 0.087 12.6 0.2 1.8 2 0 0 2 2 2 0 ALMS motif PetM PF08041.6 AEO64395.1 - 0.011 15.1 6.9 0.041 13.3 2.0 2.7 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 DUF3169 PF11368.3 AEO64395.1 - 0.042 13.0 0.2 0.042 13.0 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) Cu_amine_oxid PF01179.15 AEO64396.1 - 2e-135 451.7 0.0 2.5e-135 451.3 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 AEO64396.1 - 3.7e-20 71.8 0.1 6.3e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Peptidase_A4 PF01828.12 AEO64397.1 - 1e-54 184.8 0.0 1.1e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase A4 family 4HBT PF03061.17 AEO64398.1 - 2.1e-10 40.5 0.2 3.9e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 AEO64398.1 - 0.12 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Tfb2 PF03849.9 AEO64399.1 - 4.4e-137 456.6 0.0 5.9e-137 456.1 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 AEO64399.1 - 4.9e-07 29.5 0.0 1.1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SinI PF08671.5 AEO64399.1 - 0.16 11.3 0.4 0.75 9.2 0.0 2.3 2 0 0 2 2 2 0 Anti-repressor SinI NRDE PF05742.7 AEO64401.1 - 1.4e-34 119.6 0.0 4.5e-29 101.6 0.0 3.0 2 1 0 2 2 2 2 NRDE protein HMGL-like PF00682.14 AEO64402.1 - 5.8e-70 235.6 0.2 1.3e-69 234.4 0.1 1.6 2 0 0 2 2 2 1 HMGL-like MFS_1 PF07690.11 AEO64405.1 - 1.5e-13 50.2 57.8 4.6e-07 28.8 14.1 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 AEO64405.1 - 2.8e-07 29.1 21.6 4.7e-07 28.3 15.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zip PF02535.17 AEO64405.1 - 0.063 12.2 2.0 0.16 10.9 1.4 1.8 1 0 0 1 1 1 0 ZIP Zinc transporter RNase_H PF00075.19 AEO64406.1 - 5.4e-07 30.0 0.0 2.5e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 RNase H FAA_hydrolase PF01557.13 AEO64407.1 - 2.3e-52 177.5 0.0 3.1e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 AEO64407.1 - 1.4e-24 86.1 0.0 2.2e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Fungal_trans PF04082.13 AEO64408.1 - 5.6e-15 54.9 0.3 1.4e-14 53.6 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO64408.1 - 1.8e-08 34.1 9.1 3e-08 33.4 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CPDase PF07823.6 AEO64410.1 - 6.5e-20 71.4 0.0 7.6e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein Cupin_3 PF05899.7 AEO64410.1 - 0.071 12.4 0.2 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) EcsB PF05975.7 AEO64412.1 - 0.05 12.0 0.1 0.05 12.0 0.1 1.9 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB TRP PF06011.7 AEO64412.1 - 0.38 9.2 4.6 0.53 8.8 3.2 1.2 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF3429 PF11911.3 AEO64412.1 - 0.66 9.9 11.3 1.7 8.5 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3429) DUF2306 PF10067.4 AEO64412.1 - 0.8 9.8 11.2 0.062 13.4 2.5 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) DUF202 PF02656.10 AEO64412.1 - 2 8.7 11.1 0.59 10.3 3.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF805 PF05656.9 AEO64412.1 - 2.3 8.0 7.3 16 5.3 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF805) dCMP_cyt_deam_1 PF00383.17 AEO64413.1 - 2.8e-12 46.1 0.0 1.1e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region WD40 PF00400.27 AEO64413.1 - 2.2e-08 33.6 1.1 0.085 12.7 0.5 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat NACHT PF05729.7 AEO64413.1 - 1.2e-06 28.2 0.0 2.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.8 AEO64413.1 - 1.8e-06 27.7 0.1 3.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 AEO64413.1 - 0.00026 20.3 0.0 0.00047 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 AEO64413.1 - 0.00092 19.1 0.2 0.0053 16.6 0.1 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO64413.1 - 0.0045 16.5 0.0 0.009 15.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 AEO64413.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Cutinase LCAT PF02450.10 AEO64413.1 - 0.0092 14.9 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 AEO64413.1 - 0.032 13.9 2.2 0.19 11.4 0.1 3.3 4 1 0 4 4 4 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 AEO64413.1 - 0.035 13.6 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) AAA_16 PF13191.1 AEO64413.1 - 0.042 13.8 0.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF915 PF06028.6 AEO64413.1 - 0.052 12.6 0.0 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF3089 PF11288.3 AEO64413.1 - 0.092 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF2075 PF09848.4 AEO64413.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Torsin PF06309.6 AEO64413.1 - 0.14 12.0 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 Torsin AAA PF00004.24 AEO64413.1 - 0.15 12.2 0.0 2.8 8.1 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Gly-zipper_Omp PF13488.1 AEO64414.1 - 0.021 14.4 0.9 0.021 14.4 0.6 3.2 2 1 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.1 AEO64414.1 - 2.4 7.7 21.3 0.22 11.0 1.2 3.3 2 2 0 2 2 2 0 YMGG-like Gly-zipper Fructosamin_kin PF03881.9 AEO64415.1 - 1.7e-43 148.6 0.0 2.2e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 AEO64415.1 - 1.4e-10 41.2 0.1 2.1e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Cu-oxidase_2 PF07731.9 AEO64417.1 - 9.5e-41 138.5 8.0 7.7e-40 135.5 0.3 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 AEO64417.1 - 1.7e-39 134.1 2.4 1.7e-39 134.1 1.7 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 AEO64417.1 - 2.1e-36 125.2 0.8 4.3e-35 120.9 0.1 2.4 2 0 0 2 2 2 1 Multicopper oxidase Herpes_U34 PF04541.8 AEO64419.1 - 0.014 14.3 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus virion protein U34 AAA_12 PF13087.1 AEO64419.1 - 0.02 14.2 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Pribosyltran PF00156.22 AEO64420.1 - 1.4e-09 37.7 0.3 9.9e-09 34.9 0.2 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DUF2031 PF09592.5 AEO64420.1 - 0.16 11.1 0.1 0.24 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) DPM3 PF08285.6 AEO64422.1 - 1.4e-33 114.6 0.1 1.5e-33 114.4 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) LRR_4 PF12799.2 AEO64423.1 - 1.4e-36 123.4 30.7 1.5e-07 30.8 3.2 10.8 8 2 1 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO64423.1 - 1.6e-27 95.0 32.4 1.3e-07 31.2 4.4 9.4 5 2 4 11 11 11 8 Leucine rich repeat LRR_1 PF00560.28 AEO64423.1 - 5.6e-20 68.3 33.7 0.0034 17.2 0.6 14.6 14 2 0 14 14 14 6 Leucine Rich Repeat LRR_7 PF13504.1 AEO64423.1 - 2.2e-10 38.9 47.0 0.81 10.1 0.4 13.9 14 0 0 14 14 14 6 Leucine rich repeat LRR_6 PF13516.1 AEO64423.1 - 2.6e-09 36.1 31.9 1 9.6 0.0 11.9 12 0 0 12 12 12 3 Leucine Rich repeat LRR_9 PF14580.1 AEO64423.1 - 0.00092 18.8 7.0 3.9 6.9 0.0 5.1 2 2 3 5 5 5 1 Leucine-rich repeat Period_C PF12114.3 AEO64423.1 - 2.6 7.6 7.7 5.6 6.5 5.3 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Zn_clus PF00172.13 AEO64424.1 - 0.017 14.9 14.4 0.032 14.1 10.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SSFA2_C PF14723.1 AEO64424.1 - 0.097 12.3 0.1 0.32 10.6 0.0 1.9 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus MFS_1 PF07690.11 AEO64425.1 - 0.00023 19.9 15.7 0.00023 19.9 10.9 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily AF-4 PF05110.8 AEO64426.1 - 3.7 5.2 12.9 4.8 4.9 8.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Mito_fiss_reg PF05308.6 AEO64426.1 - 6.8 5.9 8.8 9.2 5.5 6.1 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DAHP_synth_1 PF00793.15 AEO64427.1 - 5.3e-101 336.8 0.1 6.1e-101 336.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.1 AEO64429.1 - 1e-17 63.4 0.3 1e-17 63.4 0.2 2.0 2 0 0 2 2 2 1 Cytochrome oxidase c assembly Ribosomal_L50 PF10501.4 AEO64430.1 - 8.8e-20 70.7 0.0 1.9e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal subunit 39S Ribosomal_L13e PF01294.13 AEO64431.1 - 6.7e-65 217.9 4.8 8.9e-65 217.5 3.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Thiolase_N PF00108.18 AEO64433.1 - 3.8e-73 245.7 0.2 5.7e-73 245.1 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AEO64433.1 - 7.5e-40 135.1 1.3 1.7e-39 134.0 0.9 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain DUF972 PF06156.8 AEO64434.1 - 0.031 14.6 8.4 0.63 10.4 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 AEO64434.1 - 0.12 12.8 14.0 1.7 9.1 5.8 3.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 AEO64434.1 - 3.9 6.4 10.8 7.4 5.5 7.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Cep57_CLD_2 PF14197.1 AEO64434.1 - 5.4 7.0 14.0 0.037 13.9 2.2 2.9 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 Cu-oxidase PF00394.17 AEO64435.1 - 4.1e-29 101.5 0.0 7.9e-27 94.1 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 AEO64435.1 - 6.6e-25 87.2 5.2 4.6e-22 78.0 1.7 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 AEO64435.1 - 1.4e-20 73.2 0.2 2.7e-19 69.0 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase PXB PF12828.2 AEO64436.1 - 2.1e-32 111.5 0.0 4.1e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 PX-associated DUF3818 PF12825.2 AEO64436.1 - 9.3e-15 54.1 0.0 1.3e-08 33.8 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) DUF3944 PF13099.1 AEO64436.1 - 0.046 13.2 0.6 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) IL10 PF00726.12 AEO64436.1 - 0.25 10.6 0.1 0.46 9.7 0.0 1.4 1 0 0 1 1 1 0 Interleukin 10 Pex24p PF06398.6 AEO64440.1 - 1.2e-102 343.3 0.0 1.5e-102 343.0 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin HsbA PF12296.3 AEO64441.1 - 0.037 13.8 5.7 0.052 13.4 3.5 1.7 1 1 0 1 1 1 0 Hydrophobic surface binding protein A YscJ_FliF_C PF08345.6 AEO64441.1 - 0.048 13.6 2.7 0.07 13.1 1.9 1.2 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal PAN_4 PF14295.1 AEO64443.1 - 0.00033 20.2 0.2 0.0011 18.5 0.1 1.8 1 1 0 1 1 1 1 PAN domain Peptidase_C28 PF05408.6 AEO64443.1 - 0.028 13.8 0.2 0.037 13.5 0.1 1.1 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase Acetyltransf_1 PF00583.19 AEO64444.1 - 1.8e-07 31.1 0.1 3.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 AEO64444.1 - 0.00063 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO64444.1 - 0.0016 18.5 0.1 0.0037 17.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO64444.1 - 0.0017 18.0 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 AEO64444.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Glyco_hydro_3 PF00933.16 AEO64446.1 - 2.2e-83 279.7 0.0 4.2e-83 278.7 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO64446.1 - 8.1e-45 153.0 0.0 1.2e-44 152.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO64446.1 - 2.8e-23 81.6 0.4 5e-23 80.8 0.3 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain CobU PF02283.11 AEO64448.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase CorA PF01544.13 AEO64452.1 - 2.7e-09 36.5 1.4 5.4e-09 35.5 1.0 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein YlqD PF11068.3 AEO64452.1 - 0.0022 18.0 0.8 0.0045 17.0 0.5 1.4 1 0 0 1 1 1 1 YlqD protein Transpeptidase PF00905.17 AEO64453.1 - 0.052 12.5 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Penicillin binding protein transpeptidase domain CAP_N PF01213.14 AEO64455.1 - 2.7 7.1 10.5 0.28 10.4 2.5 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PAT1 PF09770.4 AEO64455.1 - 3.8 5.6 8.1 4.2 5.4 5.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sugar_tr PF00083.19 AEO64456.1 - 9.3e-79 265.0 16.8 1.1e-78 264.8 11.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO64456.1 - 3.9e-30 104.7 13.8 6.2e-30 104.1 9.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO64456.1 - 4.8e-11 41.5 2.7 1.1e-10 40.3 0.4 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 AEO64456.1 - 5.1e-09 35.0 12.8 2.9e-08 32.5 1.6 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein Folate_carrier PF01770.13 AEO64456.1 - 0.00012 20.7 3.0 0.027 12.9 0.3 2.1 2 0 0 2 2 2 2 Reduced folate carrier Abhydrolase_6 PF12697.2 AEO64458.1 - 4.8e-09 36.4 3.2 5.6e-08 32.9 1.4 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO64458.1 - 2.4e-05 24.1 0.1 2.9e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AEO64458.1 - 0.0073 16.1 0.0 0.02 14.7 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Fungal_trans_2 PF11951.3 AEO64459.1 - 6.2e-08 31.6 0.8 5.2e-07 28.6 0.2 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO64459.1 - 7.1e-06 25.8 5.9 1.2e-05 25.1 4.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Chorion_S16 PF05836.7 AEO64459.1 - 0.044 13.6 0.2 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Chorion protein S16 adh_short PF00106.20 AEO64460.1 - 4.7e-22 78.6 0.1 6e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO64460.1 - 1.1e-08 35.1 0.0 1.6e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO64460.1 - 2e-07 30.8 0.2 4e-07 29.8 0.1 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO64460.1 - 9.3e-05 22.4 0.2 0.00022 21.2 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 AEO64460.1 - 0.022 14.8 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 AEO64460.1 - 0.031 13.2 0.6 0.045 12.7 0.4 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase ApbA PF02558.11 AEO64460.1 - 0.043 13.2 0.1 0.068 12.6 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.11 AEO64461.1 - 9.6e-47 159.3 42.3 9.6e-47 159.3 29.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO64461.1 - 7.1e-16 57.8 6.0 7.1e-16 57.8 4.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 AEO64461.1 - 1.1 7.2 12.4 0.015 13.4 3.0 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector DIM PF08194.7 AEO64462.1 - 0.11 12.4 0.1 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 DIM protein UFD1 PF03152.9 AEO64463.1 - 9.7e-24 83.4 0.0 6.9e-19 67.6 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 zf-C2H2 PF00096.21 AEO64463.1 - 3 8.3 8.5 1.5 9.3 0.3 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-AN1 PF01428.11 AEO64465.1 - 0.0021 17.8 3.7 0.0028 17.4 2.6 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger DUF326 PF03860.11 AEO64465.1 - 0.25 11.1 2.3 0.44 10.4 1.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) Peptidase_A4 PF01828.12 AEO64466.1 - 1.1e-38 132.4 1.4 1.4e-38 132.1 0.9 1.1 1 0 0 1 1 1 1 Peptidase A4 family Serglycin PF04360.7 AEO64466.1 - 0.092 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Serglycin Sugar_tr PF00083.19 AEO64467.1 - 2.5e-78 263.7 21.5 3.1e-78 263.3 14.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO64467.1 - 1.1e-18 67.1 58.0 7.9e-16 57.7 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ldh_2 PF02615.9 AEO64468.1 - 3.5e-97 325.1 0.0 4e-97 324.9 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Actin PF00022.14 AEO64469.1 - 6.4e-103 344.2 0.0 7.8e-103 343.9 0.0 1.0 1 0 0 1 1 1 1 Actin PAP_assoc PF03828.14 AEO64470.1 - 1.5e-14 53.6 0.1 2.9e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 AEO64470.1 - 1.9e-08 34.4 0.0 4.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4611 PF15387.1 AEO64470.1 - 0.24 11.5 5.3 3.4 7.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DUF3597 PF12200.3 AEO64470.1 - 1 9.7 0.0 1 9.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3597) Sugar_tr PF00083.19 AEO64471.1 - 5.6e-107 358.1 20.0 7.4e-107 357.7 13.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO64471.1 - 3.2e-23 82.0 21.8 3.2e-23 82.0 15.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF554 PF04474.7 AEO64471.1 - 0.013 14.6 3.0 0.013 14.6 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF554) YrhK PF14145.1 AEO64471.1 - 0.022 14.4 0.2 0.022 14.4 0.1 3.1 3 1 0 3 3 3 0 YrhK-like protein Glyco_hydro_2_N PF02837.13 AEO64472.1 - 2.8e-07 30.2 0.0 6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 AEO64472.1 - 6.2e-06 25.3 0.1 1.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 AEO64472.1 - 0.0015 18.9 0.0 0.0055 17.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Aldo_ket_red PF00248.16 AEO64473.1 - 1.4e-68 230.7 0.0 1.8e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ABC_tran PF00005.22 AEO64474.1 - 1.9e-64 216.0 0.0 5.1e-32 111.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AEO64474.1 - 9.5e-49 166.2 28.6 1.8e-43 148.9 12.6 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 AEO64474.1 - 1.4e-17 63.6 4.7 3.4e-07 29.7 1.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AEO64474.1 - 2.8e-15 57.0 0.1 0.0041 17.1 0.0 4.3 2 2 1 3 3 3 3 AAA domain AAA_22 PF13401.1 AEO64474.1 - 9.2e-10 38.7 2.6 0.0041 17.2 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 AEO64474.1 - 4.6e-09 35.6 2.7 0.00019 20.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 AEO64474.1 - 1e-08 34.8 0.5 0.00062 19.2 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_17 PF13207.1 AEO64474.1 - 1.2e-08 35.7 0.9 0.0047 17.7 0.0 2.8 2 2 0 2 2 2 2 AAA domain AAA_23 PF13476.1 AEO64474.1 - 2e-08 34.8 1.4 0.0021 18.4 0.0 2.5 2 1 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 AEO64474.1 - 8.2e-08 31.2 3.4 0.004 15.7 0.0 4.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class DUF258 PF03193.11 AEO64474.1 - 2.2e-07 30.1 0.0 0.02 14.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 AEO64474.1 - 3e-07 30.6 1.5 0.016 15.1 0.3 3.4 3 1 0 3 3 3 2 AAA ATPase domain SbcCD_C PF13558.1 AEO64474.1 - 1e-06 28.5 0.7 0.0023 17.7 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 AEO64474.1 - 2.4e-06 27.8 0.1 0.039 14.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.1 AEO64474.1 - 1.6e-05 24.6 0.4 0.15 11.6 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_10 PF12846.2 AEO64474.1 - 1.7e-05 24.4 1.4 0.45 9.8 0.0 3.7 4 0 0 4 4 4 2 AAA-like domain AAA_33 PF13671.1 AEO64474.1 - 2.2e-05 24.3 0.1 0.32 10.8 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 AEO64474.1 - 3.8e-05 23.3 0.0 0.27 11.0 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain MobB PF03205.9 AEO64474.1 - 4.8e-05 23.0 0.1 0.12 12.0 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 AEO64474.1 - 0.0004 19.9 0.2 1.9 7.9 0.0 3.3 3 0 0 3 3 3 2 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 AEO64474.1 - 0.0004 20.3 0.1 0.32 10.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 AEO64474.1 - 0.00043 20.4 0.6 5.5 7.1 0.0 4.3 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AEO64474.1 - 0.0012 18.5 0.0 2.7 7.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AEO64474.1 - 0.0013 18.6 0.0 5.3 6.9 0.0 3.7 4 0 0 4 4 3 0 AAA domain ATP-synt_ab PF00006.20 AEO64474.1 - 0.0023 17.4 0.0 0.23 10.9 0.0 2.8 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.17 AEO64474.1 - 0.003 17.0 0.9 4.8 6.5 0.0 3.6 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_15 PF13175.1 AEO64474.1 - 0.0038 16.3 0.0 0.12 11.3 0.0 2.3 3 0 0 3 3 2 1 AAA ATPase domain DUF87 PF01935.12 AEO64474.1 - 0.0045 16.8 0.3 1.1 8.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_11 PF13086.1 AEO64474.1 - 0.0048 16.5 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 AEO64474.1 - 0.0071 16.5 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase DUF3987 PF13148.1 AEO64474.1 - 0.0087 14.6 0.0 2 6.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_24 PF13479.1 AEO64474.1 - 0.0087 15.6 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 AEO64474.1 - 0.011 15.6 0.1 7.7 6.5 0.0 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase NB-ARC PF00931.17 AEO64474.1 - 0.012 14.4 1.2 1.9 7.2 0.0 2.7 3 0 0 3 3 2 0 NB-ARC domain IstB_IS21 PF01695.12 AEO64474.1 - 0.013 14.8 0.3 4.2 6.7 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein KaiC PF06745.8 AEO64474.1 - 0.016 14.3 1.8 0.57 9.2 0.0 2.9 3 0 0 3 3 3 0 KaiC Rad17 PF03215.10 AEO64474.1 - 0.027 13.1 0.0 4.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NACHT PF05729.7 AEO64474.1 - 0.04 13.5 0.0 9.6 5.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.13 AEO64474.1 - 0.047 13.1 0.0 10 5.5 0.0 2.8 3 0 0 3 3 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 AEO64474.1 - 0.052 12.6 0.4 2.1 7.3 0.0 2.8 3 0 0 3 3 2 0 Zeta toxin APS_kinase PF01583.15 AEO64474.1 - 0.053 13.1 0.1 7.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase cobW PF02492.14 AEO64474.1 - 0.07 12.5 0.0 8.3 5.8 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.13 AEO64474.1 - 0.081 12.4 0.0 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.10 AEO64474.1 - 0.15 11.7 3.5 14 5.3 0.0 3.8 4 0 0 4 4 4 0 NTPase Arch_ATPase PF01637.13 AEO64474.1 - 0.18 11.5 0.7 3.9 7.0 0.0 2.8 3 0 0 3 3 3 0 Archaeal ATPase Pox_A32 PF04665.7 AEO64474.1 - 0.47 9.7 2.3 8.3 5.6 0.0 2.9 3 0 0 3 3 3 0 Poxvirus A32 protein FSH1 PF03959.8 AEO64475.1 - 4.7e-33 114.4 0.0 1.3e-32 113.0 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PE-PPE PF08237.6 AEO64475.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain ketoacyl-synt PF00109.21 AEO64476.1 - 4.7e-61 206.4 0.3 2.1e-33 115.9 0.0 2.9 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 AEO64476.1 - 2e-59 200.3 4.2 3.1e-59 199.6 0.5 2.8 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 AEO64476.1 - 2.1e-57 194.8 0.0 3.3e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 AEO64476.1 - 4.4e-47 160.0 0.8 4.4e-47 160.0 0.5 2.4 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 AEO64476.1 - 7.5e-46 156.6 0.1 1.3e-45 155.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 AEO64476.1 - 4.4e-23 81.3 0.1 1.3e-21 76.6 0.0 2.8 1 1 1 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 AEO64476.1 - 1.4e-15 56.9 0.0 9.4e-15 54.3 0.0 2.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO64476.1 - 5e-13 50.0 0.0 2e-12 48.1 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO64476.1 - 4.9e-07 29.4 0.1 1.7e-06 27.7 0.1 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 AEO64476.1 - 3.4e-05 24.0 1.2 0.002 18.3 0.2 2.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site Shikimate_DH PF01488.15 AEO64476.1 - 0.028 14.5 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 AEO64476.1 - 0.81 8.8 2.2 0.57 9.3 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family MFS_1 PF07690.11 AEO64477.1 - 1.2e-23 83.4 36.2 1.2e-23 83.4 25.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO64477.1 - 1.8e-12 46.5 6.1 1.8e-12 46.5 4.3 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter ESSS PF10183.4 AEO64477.1 - 0.11 12.9 0.2 2.2 8.7 0.2 2.8 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) UQ_con PF00179.21 AEO64478.1 - 5.2e-26 90.7 0.1 7.1e-26 90.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.18 AEO64479.1 - 8.4e-37 127.3 0.0 1.2e-36 126.8 0.0 1.2 1 0 0 1 1 1 1 Surface antigen ABC2_membrane PF01061.19 AEO64480.1 - 1.7e-96 321.3 59.7 3.4e-50 170.1 15.2 3.0 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.7 AEO64480.1 - 8.2e-38 128.2 1.8 2e-34 117.3 0.1 3.4 4 0 0 4 4 2 2 CDR ABC transporter ABC_tran PF00005.22 AEO64480.1 - 4.5e-35 120.9 0.0 2.8e-16 60.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 AEO64480.1 - 6.1e-23 80.7 0.1 1.5e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 AEO64480.1 - 8.7e-08 31.7 0.0 0.0003 20.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AEO64480.1 - 7.2e-07 29.3 0.1 7.9e-05 22.7 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 AEO64480.1 - 1.2e-06 28.4 0.0 0.019 14.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 AEO64480.1 - 2.4e-06 26.8 0.1 0.00014 21.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 AEO64480.1 - 8.3e-05 21.7 40.3 0.0019 17.2 8.5 3.2 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.1 AEO64480.1 - 0.0001 21.7 0.6 0.027 14.0 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 AEO64480.1 - 0.00055 20.0 0.0 0.88 9.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 AEO64480.1 - 0.00075 18.9 0.1 0.022 14.2 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 AEO64480.1 - 0.00086 19.3 0.0 1.6 8.5 0.0 3.0 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 AEO64480.1 - 0.0009 20.0 0.0 1.2 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AEO64480.1 - 0.0043 16.7 0.2 4.5 7.1 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain SMC_N PF02463.14 AEO64480.1 - 0.0052 16.0 0.0 1.6 7.9 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 AEO64480.1 - 0.0064 16.1 0.2 1.1 8.9 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 AEO64480.1 - 0.026 14.8 0.0 0.84 9.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 AEO64480.1 - 0.067 12.8 0.2 4.1 7.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 AEO64480.1 - 0.07 13.0 0.1 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AEO64480.1 - 0.094 12.1 0.6 7.5 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 AEO64480.1 - 0.15 12.4 0.4 0.39 11.0 0.0 1.9 3 0 0 3 3 1 0 AAA domain AAA_14 PF13173.1 AEO64480.1 - 0.2 11.5 0.0 25 4.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 AEO64480.1 - 0.27 10.7 0.0 4.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Peptidase_S49_N PF08496.5 AEO64482.1 - 0.058 13.1 1.5 0.12 12.1 1.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rtf2 PF04641.7 AEO64482.1 - 0.12 11.5 2.3 0.26 10.4 1.6 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger Aldo_ket_red PF00248.16 AEO64483.1 - 1.2e-45 155.5 0.0 2.8e-45 154.3 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.19 AEO64485.1 - 1.5e-93 313.8 17.1 1.7e-93 313.6 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO64485.1 - 1.2e-29 103.1 54.9 3.7e-27 94.9 22.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 AEO64485.1 - 0.0046 16.7 2.0 2.2 8.1 0.0 3.3 3 0 0 3 3 3 2 MFS_1 like family CBM-like PF14683.1 AEO64486.1 - 6.7e-10 38.8 0.3 1.8e-05 24.4 0.1 2.0 1 1 1 2 2 2 2 Polysaccharide lyase family 4, domain III Ribosomal_S28e PF01200.13 AEO64487.1 - 1.1e-32 111.5 2.1 1.2e-32 111.4 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e ABC1 PF03109.11 AEO64489.1 - 1.2e-26 93.0 0.0 2.6e-17 62.8 0.0 2.4 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 AEO64489.1 - 0.0099 15.6 0.5 0.066 12.9 0.4 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Cyto_heme_lyase PF01265.12 AEO64490.1 - 5.9e-77 258.7 0.0 6.9e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Methyltransf_23 PF13489.1 AEO64491.1 - 1.2e-11 44.5 0.0 2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO64491.1 - 6.5e-05 23.3 0.0 0.0004 20.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO64491.1 - 0.00056 19.5 0.0 0.0049 16.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO64491.1 - 0.0021 18.5 0.0 0.0044 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO64491.1 - 0.02 15.4 0.0 0.2 12.2 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain DbpA PF03880.10 AEO64492.1 - 0.067 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 DbpA RNA binding domain VPEP PF07589.6 AEO64493.1 - 2.5 8.1 8.9 0.29 11.0 2.0 2.4 1 1 1 2 2 2 0 PEP-CTERM motif GCIP PF13324.1 AEO64496.1 - 0.00076 18.7 0.0 0.0019 17.4 0.0 1.6 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting NEMO PF11577.3 AEO64496.1 - 0.084 12.6 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO PRKCSH-like PF12999.2 AEO64497.1 - 3.7e-41 140.6 7.1 4.6e-25 88.1 0.5 3.0 3 1 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 AEO64497.1 - 1.7e-31 108.7 0.7 1.7e-31 108.7 0.5 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 AEO64497.1 - 3e-10 40.7 1.4 1e-09 39.0 1.0 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein WXG100 PF06013.7 AEO64497.1 - 0.005 16.8 2.3 11 6.0 0.0 3.4 3 0 0 3 3 3 0 Proteins of 100 residues with WXG NPV_P10 PF05531.7 AEO64497.1 - 0.011 15.9 1.2 0.34 11.1 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF684 PF05075.9 AEO64497.1 - 0.027 13.0 0.4 0.027 13.0 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF684) Fib_alpha PF08702.5 AEO64497.1 - 0.033 14.3 4.4 0.54 10.3 0.1 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.1 AEO64497.1 - 0.076 13.3 4.5 0.19 12.0 0.1 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DFF-C PF09033.5 AEO64497.1 - 0.091 12.5 5.3 0.029 14.2 1.4 1.8 1 1 1 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain GAS PF13851.1 AEO64497.1 - 0.11 11.6 15.1 2.1 7.4 6.9 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 AEO64497.1 - 0.14 11.8 7.0 2.6 7.8 4.7 2.4 1 1 1 2 2 2 0 Laminin Domain II OmpH PF03938.9 AEO64497.1 - 0.62 9.9 12.1 0.43 10.5 3.0 2.9 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) BLOC1_2 PF10046.4 AEO64497.1 - 0.86 9.7 5.1 13 5.9 0.3 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.1 AEO64497.1 - 0.96 8.3 12.4 1.3 7.8 7.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF948 PF06103.6 AEO64497.1 - 1 9.2 2.6 14 5.5 0.3 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Prefoldin_2 PF01920.15 AEO64497.1 - 1.1 9.0 21.9 1.9 8.2 0.1 3.7 4 0 0 4 4 4 0 Prefoldin subunit DUF3373 PF11853.3 AEO64497.1 - 1.7 7.0 6.6 1.6 7.1 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) Spc24 PF08286.6 AEO64497.1 - 1.8 8.2 13.4 0.24 11.0 1.3 3.1 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 DUF4047 PF13256.1 AEO64497.1 - 2.1 8.3 9.8 14 5.6 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) PilJ PF13675.1 AEO64497.1 - 3.1 8.1 8.1 8.2 6.7 0.2 3.1 2 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term FlaC_arch PF05377.6 AEO64497.1 - 5.2 7.0 6.5 15 5.5 0.3 3.1 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) PspB PF06667.7 AEO64497.1 - 6.7 6.7 9.0 0.22 11.4 0.2 2.4 2 1 0 2 2 2 0 Phage shock protein B HR1 PF02185.11 AEO64497.1 - 9.5 6.0 16.3 2.4 7.9 0.3 2.8 3 0 0 3 3 3 0 Hr1 repeat Rtf2 PF04641.7 AEO64498.1 - 2.1e-48 164.7 0.0 3.1e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.1 AEO64498.1 - 0.00018 21.1 0.1 0.00027 20.5 0.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 AEO64498.1 - 0.00024 20.7 0.4 0.00053 19.6 0.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 AEO64498.1 - 0.0041 16.9 0.1 0.0095 15.7 0.1 1.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AEO64498.1 - 0.021 14.4 0.1 0.035 13.7 0.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO64498.1 - 0.038 14.0 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.4 AEO64498.1 - 1.3 8.7 5.1 11 5.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 FAT PF02259.18 AEO64499.1 - 2.7e-125 418.0 2.3 7.4e-125 416.5 1.6 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 AEO64499.1 - 3.2e-61 206.8 0.4 9.2e-61 205.2 0.3 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 AEO64499.1 - 2.3e-57 193.3 2.3 6.4e-56 188.7 0.0 4.0 4 1 1 5 5 5 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 AEO64499.1 - 6.2e-43 144.9 1.8 1.4e-42 143.8 0.1 2.7 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 AEO64499.1 - 4.4e-16 58.9 7.9 0.0028 17.9 0.1 7.5 5 2 1 7 7 7 3 HEAT repeats HEAT PF02985.17 AEO64499.1 - 2.3e-15 55.2 14.0 0.012 15.6 0.0 10.1 10 1 0 10 10 9 5 HEAT repeat FATC PF02260.15 AEO64499.1 - 2.3e-15 55.6 0.1 7.4e-15 54.0 0.1 2.0 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 AEO64499.1 - 5.3e-09 36.2 17.5 0.0055 17.1 0.1 11.3 10 3 3 13 13 11 2 HEAT-like repeat Adaptin_N PF01602.15 AEO64499.1 - 2.3e-07 29.5 5.0 0.0073 14.6 0.2 4.1 3 1 1 4 4 4 3 Adaptin N terminal region UME PF08064.8 AEO64499.1 - 1.5e-05 24.9 0.2 0.87 9.5 0.0 4.4 4 0 0 4 4 4 2 UME (NUC010) domain Cnd1 PF12717.2 AEO64499.1 - 1.8e-05 24.6 5.0 0.099 12.4 0.1 6.1 4 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 AEO64499.1 - 0.00058 20.2 0.7 1.8e+02 2.6 0.0 6.7 5 1 2 7 7 7 0 Vacuolar 14 Fab1-binding region RVT_1 PF00078.22 AEO64500.1 - 0.0062 15.9 0.2 0.0083 15.5 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exonuc_V_gamma PF04257.9 AEO64500.1 - 0.16 9.9 0.2 0.17 9.8 0.1 1.0 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit RVT_1 PF00078.22 AEO64501.1 - 2.2e-05 23.9 0.2 2.9e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 AEO64502.1 - 0.0033 16.8 0.3 0.0045 16.3 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ACT PF01842.20 AEO64502.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 ACT domain 4HBT_2 PF13279.1 AEO64504.1 - 2.3e-06 28.0 0.0 2.9e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 AEO64504.1 - 0.00028 20.9 0.0 0.00037 20.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 AEO64504.1 - 0.00035 19.6 1.1 0.00047 19.1 0.8 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase Exo5 PF09810.4 AEO64504.1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease PseudoU_synth_2 PF00849.17 AEO64505.1 - 1.6e-29 102.8 0.0 2.7e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 AEO64505.1 - 0.00023 20.5 0.1 0.0006 19.2 0.0 1.7 2 0 0 2 2 2 1 S4 domain Ub-Mut7C PF14451.1 AEO64505.1 - 0.044 13.3 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin WASH_WAHD PF11945.3 AEO64506.1 - 0.00055 19.3 0.0 0.0008 18.7 0.0 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex LUC7 PF03194.10 AEO64506.1 - 0.0011 18.5 2.1 0.0014 18.2 1.5 1.1 1 0 0 1 1 1 1 LUC7 N_terminus bZIP_1 PF00170.16 AEO64506.1 - 0.058 13.3 13.3 0.27 11.2 9.2 1.9 1 1 0 1 1 1 0 bZIP transcription factor Mei5 PF10376.4 AEO64506.1 - 0.45 10.0 9.2 0.63 9.5 6.4 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein bZIP_2 PF07716.10 AEO64506.1 - 0.72 9.7 16.5 5.1 7.0 6.9 2.1 2 0 0 2 2 2 0 Basic region leucine zipper HemX PF04375.9 AEO64506.1 - 1.1 7.7 8.7 1.6 7.2 6.0 1.1 1 0 0 1 1 1 0 HemX DUF3435 PF11917.3 AEO64506.1 - 1.4 7.5 6.0 1.8 7.1 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF4570 PF15134.1 AEO64506.1 - 4.1 7.3 9.5 6 6.7 6.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) MFS_1 PF07690.11 AEO64507.1 - 3.6e-21 75.2 21.9 3.6e-21 75.2 15.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO64507.1 - 0.001 17.7 2.4 0.001 17.7 1.7 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 AEO64507.1 - 0.0051 15.2 9.6 0.043 12.2 2.2 2.8 3 1 0 3 3 3 2 MFS/sugar transport protein Ureidogly_hydro PF04115.7 AEO64508.1 - 4.1e-52 175.8 0.0 5.2e-52 175.5 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase SNF2_N PF00176.18 AEO64509.1 - 4.1e-16 58.6 0.0 1.4e-14 53.6 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain DNA_methylase PF00145.12 AEO64509.1 - 1.1e-12 47.8 0.0 3.6e-11 42.7 0.0 2.5 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase DUF4311 PF14188.1 AEO64509.1 - 0.38 10.2 0.2 1 8.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) ResIII PF04851.10 AEO64509.1 - 0.59 9.9 0.0 1.2 8.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-RING_5 PF14634.1 AEO64509.1 - 2.9 7.7 22.7 0.024 14.3 7.4 2.6 2 0 0 2 2 2 0 zinc-RING finger domain RasGAP PF00616.14 AEO64511.1 - 1.1e-45 155.6 0.0 4.2e-45 153.8 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 AEO64511.1 - 0.0026 17.5 0.0 0.0092 15.8 0.0 1.8 2 0 0 2 2 2 1 C2 domain Pro_isomerase PF00160.16 AEO64512.1 - 9e-48 162.3 0.3 1.3e-47 161.8 0.2 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 AEO64512.1 - 1.3e-11 43.9 8.9 4.9e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 AEO64512.1 - 5.3e-07 29.0 3.2 4.4e-05 23.0 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO64512.1 - 0.00014 21.4 1.6 0.00021 20.8 0.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 AEO64512.1 - 0.00022 21.1 1.1 0.0011 18.8 0.3 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 AEO64512.1 - 0.00075 19.9 3.8 0.0016 18.9 1.7 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 AEO64512.1 - 0.0012 18.3 0.9 0.0051 16.3 0.1 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 AEO64512.1 - 0.0022 18.3 0.9 0.01 16.2 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 AEO64512.1 - 0.74 10.5 10.1 0.5 11.1 0.6 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.11 AEO64513.1 - 2.4e-46 157.3 0.1 2.7e-46 157.1 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.10 AEO64514.1 - 1.2e-100 335.6 25.6 1.9e-100 334.9 17.8 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 AEO64514.1 - 8.4e-42 142.2 10.8 2.2e-41 140.8 7.5 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Snapin_Pallidin PF14712.1 AEO64514.1 - 0.0026 18.0 11.7 0.015 15.6 0.6 2.5 2 0 0 2 2 2 2 Snapin/Pallidin DUF2373 PF10180.4 AEO64514.1 - 0.0069 15.9 3.2 0.015 14.8 2.2 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 AEO64514.1 - 0.014 15.3 1.5 0.014 15.3 1.0 3.4 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF1192 PF06698.6 AEO64514.1 - 0.017 14.9 2.1 0.017 14.9 1.5 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) Osmo_CC PF08946.5 AEO64514.1 - 0.023 14.6 0.2 0.023 14.6 0.1 2.8 2 1 0 2 2 1 0 Osmosensory transporter coiled coil Sec5 PF15469.1 AEO64514.1 - 0.071 12.8 12.0 0.19 11.4 1.7 2.4 2 0 0 2 2 2 0 Exocyst complex component Sec5 Poty_PP PF08440.5 AEO64514.1 - 0.095 11.7 4.9 0.065 12.2 1.3 2.0 2 0 0 2 2 2 0 Potyviridae polyprotein Syntaxin_2 PF14523.1 AEO64514.1 - 0.38 10.7 10.4 0.13 12.3 3.9 2.4 2 0 0 2 2 2 0 Syntaxin-like protein CorA PF01544.13 AEO64514.1 - 6.6 5.6 8.7 0.69 8.8 1.3 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein zf-C2H2 PF00096.21 AEO64515.1 - 0.012 15.8 13.3 0.074 13.4 0.0 4.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO64515.1 - 0.032 14.5 18.9 0.036 14.4 0.1 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger Iso_dh PF00180.15 AEO64516.1 - 8.2e-71 238.7 0.0 9.7e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ino80_Iec3 PF14612.1 AEO64517.1 - 1.2e-66 225.0 5.0 9.7e-35 120.6 1.0 2.1 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling HTH_28 PF13518.1 AEO64517.1 - 0.027 14.4 0.3 13 5.8 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain UPF0160 PF03690.8 AEO64518.1 - 6.6e-123 410.1 0.0 7.4e-123 410.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Endosulfine PF04667.12 AEO64519.1 - 1.2e-20 73.2 0.0 1.2e-20 73.2 0.0 2.3 2 1 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region Spt20 PF12090.3 AEO64519.1 - 0.069 12.5 1.2 0.07 12.4 0.8 1.2 1 0 0 1 1 1 0 Spt20 family ERF PF04404.7 AEO64519.1 - 2.6 7.5 10.9 4.7 6.7 7.6 1.4 1 0 0 1 1 1 0 ERF superfamily DUF1793 PF08760.6 AEO64520.1 - 8.9e-64 214.4 0.1 1.9e-63 213.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) PGAP1 PF07819.8 AEO64521.1 - 5.1e-09 36.0 0.0 8.6e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 AEO64521.1 - 3.1e-08 33.8 0.3 5.4e-08 33.0 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 AEO64521.1 - 8.4e-06 25.0 0.0 1.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 AEO64521.1 - 0.00018 20.8 0.1 0.00041 19.7 0.1 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 AEO64521.1 - 0.0017 17.9 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 AEO64521.1 - 0.0033 17.6 0.0 0.0059 16.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 AEO64521.1 - 0.012 15.3 0.1 0.026 14.2 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Lipase_2 PF01674.13 AEO64521.1 - 0.016 14.5 0.0 0.055 12.7 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 2) DUF915 PF06028.6 AEO64521.1 - 0.027 13.5 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.7 AEO64521.1 - 0.033 13.5 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.8 AEO64521.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase RTA1 PF04479.8 AEO64522.1 - 6.4e-13 48.7 14.4 9.3e-13 48.1 10.0 1.2 1 0 0 1 1 1 1 RTA1 like protein Neisseria_TspB PF05616.8 AEO64522.1 - 0.34 9.2 1.4 0.5 8.6 1.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein CENP-F_leu_zip PF10473.4 AEO64523.1 - 7.9e-06 25.7 1.0 1.3e-05 25.0 0.7 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HR1 PF02185.11 AEO64523.1 - 0.00011 21.8 0.6 0.0066 16.1 0.2 2.5 1 1 2 3 3 3 1 Hr1 repeat TMF_DNA_bd PF12329.3 AEO64523.1 - 0.002 17.9 1.2 0.018 14.8 0.2 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Filament PF00038.16 AEO64523.1 - 0.0025 17.3 0.2 0.0036 16.8 0.2 1.2 1 0 0 1 1 1 1 Intermediate filament protein Seryl_tRNA_N PF02403.17 AEO64523.1 - 0.0045 16.9 2.2 0.3 11.1 0.3 2.2 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.6 AEO64523.1 - 0.0065 16.3 0.3 0.056 13.3 0.1 2.2 2 1 0 2 2 2 1 Flagella accessory protein C (FlaC) IncA PF04156.9 AEO64523.1 - 0.0082 15.7 5.3 0.0082 15.7 3.7 1.9 2 1 0 2 2 1 1 IncA protein DUF2968 PF11180.3 AEO64523.1 - 0.0087 15.4 3.3 0.014 14.8 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Spc7 PF08317.6 AEO64523.1 - 0.0089 14.7 0.1 0.013 14.1 0.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4164 PF13747.1 AEO64523.1 - 0.011 15.8 2.7 0.011 15.8 1.9 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4164) Atg14 PF10186.4 AEO64523.1 - 0.013 14.4 0.2 0.02 13.8 0.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Nsp1_C PF05064.8 AEO64523.1 - 0.018 14.6 1.2 0.035 13.7 0.2 1.8 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF869 PF05911.6 AEO64523.1 - 0.02 13.1 0.7 0.026 12.7 0.5 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) V_ATPase_I PF01496.14 AEO64523.1 - 0.022 12.6 0.0 0.033 12.0 0.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.7 AEO64523.1 - 0.023 13.1 3.8 0.027 12.9 2.2 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family APG6 PF04111.7 AEO64523.1 - 0.028 13.4 0.5 0.041 12.9 0.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Laminin_II PF06009.7 AEO64523.1 - 0.037 13.7 0.3 0.055 13.2 0.2 1.2 1 0 0 1 1 1 0 Laminin Domain II bZIP_2 PF07716.10 AEO64523.1 - 0.046 13.5 3.7 9.4 6.1 0.0 2.7 2 1 1 3 3 3 0 Basic region leucine zipper TBPIP PF07106.8 AEO64523.1 - 0.059 12.9 1.5 0.55 9.7 0.4 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 AEO64523.1 - 0.066 11.6 0.1 0.091 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PspA_IM30 PF04012.7 AEO64523.1 - 0.068 12.5 8.8 1.2 8.3 2.9 2.2 1 1 1 2 2 2 0 PspA/IM30 family Med9 PF07544.8 AEO64523.1 - 0.081 12.6 2.8 1.1 9.0 2.0 2.2 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Syntaphilin PF15290.1 AEO64523.1 - 0.088 12.2 1.2 0.14 11.6 0.9 1.3 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp CCDC-167 PF15188.1 AEO64523.1 - 0.094 12.6 3.0 0.47 10.4 0.8 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Rho_Binding PF08912.6 AEO64523.1 - 0.096 12.9 2.3 0.099 12.9 0.3 1.8 2 0 0 2 2 2 0 Rho Binding IFT57 PF10498.4 AEO64523.1 - 0.11 11.2 0.1 0.21 10.2 0.0 1.4 2 0 0 2 2 1 0 Intra-flagellar transport protein 57 Prefoldin_2 PF01920.15 AEO64523.1 - 0.11 12.2 3.5 0.31 10.8 1.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit Troponin PF00992.15 AEO64523.1 - 0.17 11.9 2.5 1.1 9.3 1.5 2.0 1 1 1 2 2 2 0 Troponin DUF972 PF06156.8 AEO64523.1 - 0.22 11.8 0.8 0.92 9.8 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ATG16 PF08614.6 AEO64523.1 - 0.24 11.2 3.3 0.46 10.2 2.3 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) YscO PF07321.7 AEO64523.1 - 0.26 11.1 6.2 0.7 9.7 4.4 1.6 1 1 0 1 1 1 0 Type III secretion protein YscO HALZ PF02183.13 AEO64523.1 - 0.27 10.9 5.4 8.1 6.2 1.5 2.7 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF3584 PF12128.3 AEO64523.1 - 0.28 8.4 2.3 0.37 8.0 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Cob_adeno_trans PF01923.13 AEO64523.1 - 0.37 10.5 4.0 1.1 8.9 0.2 2.4 2 1 0 2 2 2 0 Cobalamin adenosyltransferase SlyX PF04102.7 AEO64523.1 - 0.52 10.7 3.4 6.6 7.1 0.1 2.7 2 1 0 2 2 2 0 SlyX Tropomyosin_1 PF12718.2 AEO64523.1 - 0.52 10.1 5.7 7.9 6.3 4.2 2.1 1 1 1 2 2 2 0 Tropomyosin like DUF4200 PF13863.1 AEO64523.1 - 0.6 10.0 5.0 4.4 7.2 3.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) ADIP PF11559.3 AEO64523.1 - 0.74 9.7 4.0 0.86 9.4 1.4 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 AEO64523.1 - 1.4 8.4 10.7 0.065 12.7 0.5 2.5 3 0 0 3 3 2 0 Septum formation initiator CENP-Q PF13094.1 AEO64523.1 - 1.8 8.5 8.7 0.83 9.6 2.9 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4140 PF13600.1 AEO64523.1 - 2.1 8.8 9.3 2.2 8.7 2.9 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TPR_MLP1_2 PF07926.7 AEO64523.1 - 6 6.6 7.0 6.1 6.5 1.8 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HrpB7 PF09486.5 AEO64523.1 - 6.6 6.6 10.2 0.27 11.1 0.7 2.5 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) NAD_binding_6 PF08030.7 AEO64524.1 - 1.6e-20 73.6 0.0 2.4e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 AEO64524.1 - 3.3e-13 49.3 0.0 6.5e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 AEO64524.1 - 1e-10 41.7 11.5 1.8e-10 40.9 8.0 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 AEO64524.1 - 0.00044 20.7 0.0 0.15 12.6 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain CBM_48 PF02922.13 AEO64525.1 - 0.022 14.7 0.2 0.055 13.5 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) zf-C3HC4_2 PF13923.1 AEO64526.1 - 1e-07 31.8 8.6 1.9e-07 30.9 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO64526.1 - 1.1e-07 31.3 7.5 2e-07 30.5 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO64526.1 - 1.4e-07 31.1 6.5 2.7e-07 30.3 4.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AEO64526.1 - 2.9e-07 30.0 5.7 5.2e-07 29.2 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO64526.1 - 2.8e-06 26.9 5.4 5.2e-06 26.0 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AEO64526.1 - 6.5e-05 22.7 7.1 0.00043 20.0 5.0 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 AEO64526.1 - 0.006 16.2 7.3 0.015 15.0 5.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger TerY-C PF15616.1 AEO64526.1 - 0.3 11.0 3.4 1.2 9.0 2.3 1.9 1 1 0 1 1 1 0 TerY-C metal binding domain zf-MIZ PF02891.15 AEO64526.1 - 0.76 9.3 9.7 3.8 7.0 7.0 2.0 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger FYVE PF01363.16 AEO64526.1 - 1.4 8.8 4.1 3.5 7.5 2.8 1.6 1 1 0 1 1 1 0 FYVE zinc finger NUFIP2 PF15293.1 AEO64527.1 - 0.11 11.2 5.6 0.14 10.8 3.9 1.0 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 DUF1180 PF06679.7 AEO64528.1 - 0.51 10.2 9.6 0.061 13.2 3.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) CFEM PF05730.6 AEO64528.1 - 1.4 8.8 13.0 3.1 7.6 8.8 1.8 1 1 0 1 1 1 0 CFEM domain Ion_trans PF00520.26 AEO64529.1 - 2e-08 33.7 6.1 2e-08 33.7 4.2 1.4 2 0 0 2 2 2 1 Ion transport protein bZIP_1 PF00170.16 AEO64529.1 - 0.0039 17.1 0.1 0.0081 16.0 0.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AEO64529.1 - 0.0046 16.7 1.9 0.011 15.5 1.3 1.6 1 0 0 1 1 1 1 Basic region leucine zipper DUF1122 PF06557.6 AEO64529.1 - 0.056 12.6 0.2 0.086 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) ELMO_CED12 PF04727.8 AEO64529.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 ELMO/CED-12 family Herpes_BLRF2 PF05812.7 AEO64529.1 - 0.12 12.2 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF4588 PF15251.1 AEO64530.1 - 2e-05 24.7 4.6 5.5e-05 23.2 3.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) SNF2_N PF00176.18 AEO64531.1 - 1.1e-82 277.1 0.2 1.7e-82 276.5 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 AEO64531.1 - 3.5e-46 155.7 3.4 1.2e-45 153.9 2.2 2.2 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 AEO64531.1 - 9.1e-38 129.1 3.7 9.1e-38 129.1 2.6 3.5 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 AEO64531.1 - 4e-15 55.4 0.0 2.2e-14 53.0 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 AEO64531.1 - 3.3e-08 32.7 0.0 8e-08 31.4 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 AEO64531.1 - 4.7e-08 33.0 0.2 1.2e-06 28.5 0.0 3.3 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AEO64531.1 - 2e-05 24.1 0.0 5.7e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 AEO64531.1 - 0.033 13.5 0.1 0.077 12.3 0.1 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 AEO64531.1 - 0.042 13.7 0.1 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 AEO64532.1 - 3.9e-32 108.9 0.2 2.1e-11 43.2 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 AEO64532.1 - 4.5e-05 21.7 0.0 6.2e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AEO64532.1 - 0.00023 20.0 0.0 0.0051 15.6 0.0 2.1 1 1 1 2 2 2 1 Nup133 N terminal like Coatomer_WDAD PF04053.9 AEO64532.1 - 0.00027 19.8 0.1 0.16 10.7 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 AEO64532.1 - 0.00043 20.0 0.2 0.75 9.4 0.0 3.3 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 AEO64532.1 - 0.12 11.7 0.8 1.4 8.2 0.4 2.0 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain FTHFS PF01268.14 AEO64533.1 - 2.1e-259 861.2 0.1 2.7e-259 860.8 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 AEO64533.1 - 1.3e-67 225.8 0.8 1.3e-67 225.8 0.5 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 AEO64533.1 - 1.1e-39 135.1 0.2 2.2e-39 134.1 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain zf-C2H2 PF00096.21 AEO64534.1 - 4.3e-09 36.1 9.8 7e-05 22.9 1.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 AEO64534.1 - 5.4e-09 35.3 0.7 0.0001 21.2 0.0 2.8 3 0 0 3 3 3 2 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 AEO64534.1 - 3.1e-07 30.2 9.5 0.0013 18.9 0.8 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO64534.1 - 1.9 8.9 11.8 0.036 14.3 0.7 2.9 3 0 0 3 3 3 0 Zinc-finger double domain CTP_transf_2 PF01467.21 AEO64535.1 - 4.3e-23 82.1 0.0 7.4e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase F-box-like PF12937.2 AEO64536.1 - 0.032 13.9 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 F-box-like Tctex-1 PF03645.8 AEO64537.1 - 1.8e-32 111.1 0.0 2.2e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.10 AEO64538.1 - 1.1e-13 51.2 5.4 1.2e-13 51.0 2.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF983 PF06170.7 AEO64538.1 - 0.16 12.1 1.1 7.6 6.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF983) DUF2615 PF11027.3 AEO64538.1 - 1.6 8.6 3.5 3.3 7.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) 7TMR-DISM_7TM PF07695.6 AEO64538.1 - 1.7 8.2 9.0 6.6 6.3 6.3 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling Alba PF01918.16 AEO64539.1 - 6.9e-06 25.5 0.0 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Alba Nop14 PF04147.7 AEO64540.1 - 1.2 7.0 9.2 1.7 6.4 6.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 AEO64540.1 - 6.1 4.7 7.2 8.6 4.2 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Plus-3 PF03126.13 AEO64541.1 - 6e-35 119.5 0.0 1.3e-34 118.4 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain COQ7 PF03232.8 AEO64542.1 - 8.2e-62 207.6 0.0 9.8e-62 207.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 AEO64542.1 - 0.0066 16.7 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Rubrerythrin Pex14_N PF04695.8 AEO64542.1 - 0.045 13.8 4.7 0.07 13.1 3.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.4 AEO64542.1 - 0.052 13.0 6.6 0.078 12.4 4.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF605 PF04652.11 AEO64542.1 - 0.088 12.1 4.9 0.096 12.0 3.4 1.1 1 0 0 1 1 1 0 Vta1 like CAF-1_p150 PF11600.3 AEO64542.1 - 4.2 6.7 8.8 6 6.1 6.1 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MSA-2c PF12238.3 AEO64542.1 - 6.2 6.4 6.4 10 5.6 4.5 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c PLDc PF00614.17 AEO64543.1 - 2.4e-16 58.9 0.9 8.5e-08 31.7 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 AEO64543.1 - 5.6e-12 45.5 0.1 1.4e-07 31.3 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PX PF00787.19 AEO64543.1 - 1.6e-07 31.0 0.0 2.4e-06 27.3 0.0 2.5 1 1 0 1 1 1 1 PX domain Tubulin PF00091.20 AEO64544.1 - 2.2e-74 249.8 0.0 3.1e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AEO64544.1 - 7.9e-46 155.1 0.3 1.6e-45 154.1 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 AEO64544.1 - 3.9e-08 33.3 0.0 7.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 AEO64544.1 - 0.056 12.8 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Tubulin domain Oxidored_q6 PF01058.17 AEO64545.1 - 3.8e-22 78.3 0.0 5.4e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Mpp10 PF04006.7 AEO64546.1 - 4.4e-92 309.3 81.5 3.1e-84 283.4 19.7 2.8 1 1 1 2 2 2 2 Mpp10 protein SPX PF03105.14 AEO64547.1 - 1.8e-21 77.1 1.9 3e-12 46.9 0.0 3.2 2 2 1 3 3 3 2 SPX domain Ribosomal_S2 PF00318.15 AEO64547.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S2 CcmD PF04995.9 AEO64547.1 - 1.7 8.4 6.8 1.2 8.8 0.1 2.6 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) NMO PF03060.10 AEO64548.1 - 8.5e-46 156.6 10.8 2.9e-37 128.5 5.3 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 AEO64548.1 - 1.5e-08 33.9 4.2 0.00093 18.1 6.8 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 AEO64548.1 - 1.2e-07 30.8 11.3 1.8e-07 30.3 7.8 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 AEO64548.1 - 6.6e-05 21.9 7.0 9.7e-05 21.4 4.9 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Amidohydro_3 PF07969.6 AEO64549.1 - 1.3e-53 182.6 0.4 1.7e-53 182.3 0.3 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 AEO64549.1 - 0.0026 17.4 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family HECT PF00632.20 AEO64550.1 - 1.9e-92 309.8 0.0 2.7e-92 309.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 AEO64550.1 - 8.3e-34 115.0 18.6 7.7e-12 44.8 2.4 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 AEO64550.1 - 3.2e-17 62.1 0.2 1.1e-16 60.4 0.1 1.9 1 0 0 1 1 1 1 C2 domain RRM_6 PF14259.1 AEO64551.1 - 2.4e-16 59.4 0.4 5.8e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO64551.1 - 2.7e-16 58.9 0.0 4.3e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO64551.1 - 6.7e-07 29.0 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.6 AEO64551.1 - 0.0054 17.1 14.4 0.0054 17.1 10.0 1.8 2 1 0 2 2 2 1 Glycine rich protein family V_ATPase_I PF01496.14 AEO64551.1 - 0.019 12.8 0.4 0.021 12.7 0.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Filament PF00038.16 AEO64551.1 - 0.034 13.6 3.3 0.046 13.1 2.3 1.1 1 0 0 1 1 1 0 Intermediate filament protein IncA PF04156.9 AEO64551.1 - 0.04 13.5 1.3 0.051 13.1 0.9 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 AEO64551.1 - 0.21 10.5 1.3 0.24 10.3 0.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 AEO64551.1 - 0.43 10.0 4.5 0.64 9.5 3.1 1.2 1 0 0 1 1 1 0 Septum formation initiator WD40 PF00400.27 AEO64553.1 - 3.5e-50 166.1 24.7 1.9e-08 33.8 0.2 11.3 12 0 0 12 12 12 9 WD domain, G-beta repeat Nup160 PF11715.3 AEO64553.1 - 0.0016 16.7 0.5 0.0068 14.5 0.1 2.1 2 1 0 3 3 3 1 Nucleoporin Nup120/160 PD40 PF07676.7 AEO64553.1 - 0.014 15.0 0.1 5 6.9 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Lactonase PF10282.4 AEO64553.1 - 0.031 13.3 0.0 0.099 11.7 0.0 1.9 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Glyco_tran_28_C PF04101.11 AEO64554.1 - 1.7e-13 50.5 0.0 4.3e-13 49.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain CHCH PF06747.8 AEO64554.1 - 0.08 12.8 0.1 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 CHCH domain DAGK_cat PF00781.19 AEO64554.1 - 0.11 11.9 0.7 0.34 10.3 0.2 1.9 1 1 1 2 2 2 0 Diacylglycerol kinase catalytic domain MRP-S28 PF10213.4 AEO64555.1 - 9.3e-49 164.7 0.5 2.1e-48 163.5 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein DUF3106 PF11304.3 AEO64555.1 - 0.13 12.6 0.1 0.13 12.6 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) Aldedh PF00171.17 AEO64556.1 - 1.3e-81 274.2 0.0 1.6e-81 274.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ECR1_N PF14382.1 AEO64557.1 - 1.4e-11 43.4 0.1 3.1e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 AEO64557.1 - 0.0024 17.7 0.1 0.017 15.0 0.0 2.3 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 AEO64557.1 - 0.0074 16.3 1.3 3.1 7.9 0.0 3.7 4 1 0 4 4 4 2 S1 RNA binding domain Acyl_transf_1 PF00698.16 AEO64558.1 - 1.3e-19 70.7 0.1 1.3e-13 50.9 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain Glyco_transf_90 PF05686.7 AEO64559.1 - 1.9e-21 76.2 0.0 3.7e-19 68.7 0.0 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 90 Nucleoporin_C PF03177.9 AEO64561.1 - 2.4e-106 356.5 13.4 3.4e-106 356.0 9.3 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 AEO64561.1 - 2.1e-92 310.0 0.0 2.8e-92 309.6 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.20 AEO64562.1 - 1.8e-36 125.6 0.0 2.5e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO64562.1 - 3.4e-14 52.5 0.0 4.6e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO64562.1 - 0.014 15.1 0.0 0.47 10.1 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF605 PF04652.11 AEO64562.1 - 3.9 6.7 11.2 5.1 6.3 7.8 1.2 1 0 0 1 1 1 0 Vta1 like EMP24_GP25L PF01105.19 AEO64563.1 - 2.1e-51 174.2 0.0 2.4e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4140 PF13600.1 AEO64563.1 - 0.013 15.9 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Shugoshin_N PF07558.6 AEO64563.1 - 0.12 12.0 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region HEAT_2 PF13646.1 AEO64567.1 - 0.049 13.9 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 HEAT repeats Hexapep PF00132.19 AEO64568.1 - 2.1e-14 52.2 21.4 8.8e-11 40.8 1.7 3.8 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AEO64568.1 - 1.2e-13 50.3 21.0 2.4e-09 36.5 0.9 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 AEO64568.1 - 1.1e-11 44.5 0.0 1.9e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Adap_comp_sub PF00928.16 AEO64570.1 - 1.7e-66 223.9 0.0 3.3e-66 223.0 0.0 1.4 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AEO64570.1 - 0.00026 20.7 0.0 0.00039 20.1 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SNO PF01174.14 AEO64570.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family DUF4536 PF15055.1 AEO64571.1 - 9.1e-05 22.4 3.1 0.00013 21.9 2.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) NAD_binding_8 PF13450.1 AEO64571.1 - 0.0027 17.7 0.7 0.0038 17.2 0.5 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF4190 PF13828.1 AEO64571.1 - 0.57 9.7 3.2 0.15 11.6 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Glyco_hydro_6 PF01341.12 AEO64572.1 - 1.2e-100 336.8 0.3 1.5e-100 336.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 adh_short PF00106.20 AEO64575.1 - 3.1e-31 108.5 0.6 4.6e-31 107.9 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO64575.1 - 4.4e-20 72.4 0.0 6.1e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO64575.1 - 4.5e-11 42.7 0.2 6.7e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO64575.1 - 1.7e-08 34.7 0.7 2.4e-08 34.1 0.5 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 AEO64575.1 - 3.3e-07 29.8 0.1 1.3e-06 27.9 0.4 1.6 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 AEO64575.1 - 1e-05 25.0 0.1 2.8e-05 23.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 AEO64575.1 - 0.0066 15.3 0.1 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.5 AEO64575.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) QRPTase_C PF01729.14 AEO64575.1 - 0.035 13.6 0.1 0.054 13.0 0.1 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Eno-Rase_NADH_b PF12242.3 AEO64575.1 - 0.044 13.5 0.2 0.098 12.4 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CpcD PF01383.16 AEO64575.1 - 0.071 13.2 0.9 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 CpcD/allophycocyanin linker domain Ribosomal_L18e PF00828.14 AEO64576.1 - 6.3e-27 94.4 0.4 6.3e-27 94.4 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 FtsJ PF01728.14 AEO64577.1 - 3.1e-58 196.7 0.0 4.1e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 AEO64577.1 - 0.00022 21.7 0.1 0.0019 18.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO64577.1 - 0.0042 16.8 0.0 0.011 15.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO64577.1 - 0.019 14.5 0.0 4.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 AEO64577.1 - 0.03 14.3 0.0 0.066 13.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Cortex-I_coil PF09304.5 AEO64578.1 - 0.0055 16.7 2.8 0.0069 16.4 1.9 1.2 1 0 0 1 1 1 1 Cortexillin I, coiled coil CENP-F_leu_zip PF10473.4 AEO64578.1 - 0.024 14.5 2.9 0.031 14.1 2.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Synaptobrevin PF00957.16 AEO64578.1 - 0.11 12.0 1.4 0.19 11.3 0.8 1.5 1 1 0 1 1 1 0 Synaptobrevin IncA PF04156.9 AEO64578.1 - 0.55 9.7 3.6 0.75 9.3 2.5 1.2 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 AEO64578.1 - 1 8.9 5.6 1.7 8.2 3.6 1.6 1 1 0 1 1 1 0 Septum formation initiator OST3_OST6 PF04756.8 AEO64579.1 - 2.1e-21 76.1 0.3 3e-21 75.6 0.2 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 AEO64579.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin 7TMR-DISM_7TM PF07695.6 AEO64579.1 - 0.27 10.8 8.7 3 7.4 6.1 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Abi PF02517.11 AEO64579.1 - 5.8 7.1 7.7 21 5.3 5.5 1.8 1 1 0 1 1 1 0 CAAX protease self-immunity Mito_carr PF00153.22 AEO64580.1 - 5.9e-75 247.0 1.7 2.8e-24 84.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.11 AEO64580.1 - 0.034 14.0 0.2 16 5.3 0.0 3.1 4 0 0 4 4 4 0 Colicin V production protein Mito_fiss_reg PF05308.6 AEO64580.1 - 4.6 6.5 9.9 6.5 6.0 6.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator APH PF01636.18 AEO64582.1 - 0.016 14.9 1.0 0.03 14.0 0.7 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Asp_Arg_Hydrox PF05118.10 AEO64582.1 - 0.027 14.3 0.2 0.08 12.7 0.0 1.8 2 0 0 2 2 2 0 Aspartyl/Asparaginyl beta-hydroxylase AsiA PF09010.5 AEO64582.1 - 0.12 12.2 0.2 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 Anti-Sigma Factor A RRM_1 PF00076.17 AEO64583.1 - 6e-12 45.0 0.0 8e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO64583.1 - 8.1e-08 32.1 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO64583.1 - 1.1e-07 31.6 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO64583.1 - 0.00034 20.3 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MBOAT PF03062.14 AEO64584.1 - 1.9e-25 89.6 22.3 8.6e-25 87.5 13.9 2.3 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 AEO64584.1 - 1.3e-06 28.3 4.1 3.6e-06 26.9 2.9 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family tRNA-synt_1b PF00579.20 AEO64585.1 - 2.6e-58 197.4 0.0 3.3e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) SPACA7 PF15307.1 AEO64585.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Sperm acrosome-associated protein 7 CH PF00307.26 AEO64586.1 - 3.5e-58 194.3 0.0 1.2e-15 57.5 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 AEO64586.1 - 3.2e-06 27.1 0.2 6e-05 23.0 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 AEO64586.1 - 0.0026 16.9 1.1 0.35 10.2 0.1 3.4 3 0 0 3 3 3 1 EF hand CAMSAP_CH PF11971.3 AEO64586.1 - 0.037 13.6 0.0 26 4.5 0.0 3.3 3 0 0 3 3 3 0 CAMSAP CH domain EF-hand_6 PF13405.1 AEO64586.1 - 0.053 13.4 3.5 0.16 11.9 0.1 3.0 3 0 0 3 3 3 0 EF-hand domain Rieske PF00355.21 AEO64588.1 - 8.8e-11 41.2 0.0 1.3e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 AEO64588.1 - 9.5e-05 22.0 0.0 0.00021 20.9 0.0 1.5 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain MFS_1 PF07690.11 AEO64589.1 - 2.5e-31 108.7 35.1 1e-28 100.0 16.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 AEO64590.1 - 1.1e-15 57.1 0.0 2.5e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 DUF1772 PF08592.6 AEO64591.1 - 0.00091 18.9 8.0 0.0013 18.4 5.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF606 PF04657.8 AEO64591.1 - 0.85 9.6 3.7 0.35 10.9 0.7 1.7 2 1 0 2 2 2 0 Protein of unknown function, DUF606 Tannase PF07519.6 AEO64592.1 - 2.5e-113 379.2 1.6 3.2e-113 378.9 1.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 AEO64592.1 - 1.9e-05 24.4 0.1 0.035 13.8 0.0 2.5 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO64592.1 - 0.00022 21.1 0.0 0.00057 19.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO64592.1 - 0.0011 18.5 0.6 0.0039 16.7 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AEO64592.1 - 0.031 13.5 0.1 1.8 7.7 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Glyco_hydro_61 PF03443.9 AEO64593.1 - 1.2e-49 169.1 0.8 1.4e-49 168.8 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TMEM171 PF15471.1 AEO64594.1 - 0.78 8.4 3.1 1.4 7.6 2.1 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Fungal_trans_2 PF11951.3 AEO64595.1 - 4.9e-11 41.8 0.9 1.4e-08 33.7 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO64595.1 - 1.2e-06 28.3 11.2 1.2e-06 28.3 7.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_15 PF00723.16 AEO64596.1 - 6e-109 364.5 0.3 7.6e-109 364.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 AEO64596.1 - 5.3e-32 109.3 0.1 1.3e-31 108.0 0.1 1.7 1 0 0 1 1 1 1 Starch binding domain Cu-oxidase_3 PF07732.10 AEO64597.1 - 3.4e-12 46.1 0.0 7.4e-08 32.1 0.1 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 AEO64597.1 - 2e-06 27.3 0.1 0.013 14.9 0.1 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.1 AEO64597.1 - 0.019 14.8 0.0 1.4 8.8 0.0 2.4 2 1 0 2 2 2 0 Cupredoxin-like domain zf-C3HC4_4 PF15227.1 AEO64598.1 - 0.0039 17.0 2.3 0.0084 15.9 1.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 AEO64598.1 - 0.011 15.4 8.0 0.025 14.4 5.6 1.6 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 AEO64598.1 - 1 9.4 7.6 0.19 11.8 2.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 AEO64598.1 - 1 8.9 5.0 0.14 11.7 0.7 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 AEO64598.1 - 7.1 6.3 6.9 22 4.8 4.8 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DDHD PF02862.12 AEO64599.1 - 5.5e-77 258.6 9.1 1.8e-75 253.6 1.1 3.3 2 1 0 2 2 2 1 DDHD domain DUF2305 PF10230.4 AEO64599.1 - 0.024 14.0 0.0 0.071 12.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 AEO64599.1 - 0.052 13.3 0.0 0.31 10.7 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family FKBP_N PF01346.13 AEO64599.1 - 5.9 6.9 19.0 0.88 9.6 2.2 3.1 2 1 1 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase RNA_pol_Rpb1_5 PF04998.12 AEO64600.1 - 1.4e-87 293.5 0.1 2.4e-87 292.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 AEO64600.1 - 6.5e-83 278.7 0.0 1e-82 278.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 AEO64600.1 - 2.9e-67 225.7 0.0 7e-67 224.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 AEO64600.1 - 9.9e-35 119.6 0.0 2.4e-34 118.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 AEO64600.1 - 9.8e-34 115.3 0.1 3.6e-33 113.5 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF159 PF02586.9 AEO64601.1 - 5.6e-55 186.0 0.0 7.9e-55 185.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 GMC_oxred_N PF00732.14 AEO64604.1 - 2.3e-23 82.7 0.0 5.5e-23 81.5 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO64604.1 - 5.2e-22 78.7 0.1 9.5e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 AEO64604.1 - 8.2e-08 31.5 0.0 0.00019 20.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 AEO64604.1 - 2.5e-06 26.6 0.3 6.8e-05 21.9 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO64604.1 - 6.7e-05 22.8 0.0 0.0002 21.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DOMON PF03351.12 AEO64604.1 - 0.00023 21.1 0.0 0.00061 19.7 0.0 1.7 1 0 0 1 1 1 1 DOMON domain Pyr_redox_2 PF07992.9 AEO64604.1 - 0.0003 20.7 0.1 0.00053 19.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO64604.1 - 0.00087 19.4 0.3 0.0019 18.3 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO64604.1 - 0.001 17.6 0.1 0.0014 17.1 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 AEO64604.1 - 0.0011 18.0 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 AEO64604.1 - 0.0029 16.7 0.1 0.059 12.4 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 AEO64604.1 - 0.029 13.2 0.3 0.071 12.0 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 AEO64604.1 - 0.052 13.9 0.0 0.3 11.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 AEO64604.1 - 0.075 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.17 AEO64604.1 - 0.076 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyco_hydro_61 PF03443.9 AEO64605.1 - 1.6e-41 142.5 0.1 1.9e-41 142.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 KR PF08659.5 AEO64607.1 - 1.2e-12 47.8 0.0 1.8e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 AEO64607.1 - 2.8e-07 30.6 0.0 4.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase SH3_3 PF08239.6 AEO64608.1 - 2.5e-07 30.7 0.1 5.3e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.8 AEO64608.1 - 0.027 13.9 0.1 0.17 11.4 0.0 2.3 4 0 0 4 4 4 0 Bacterial SH3 domain DUF4419 PF14388.1 AEO64609.1 - 5.7e-77 258.8 0.0 7.6e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) GTP_cyclohydroI PF01227.17 AEO64611.1 - 1.3e-73 246.1 0.2 1.5e-73 245.9 0.1 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 AEO64611.1 - 0.0021 17.9 0.1 0.0044 16.9 0.0 1.6 2 0 0 2 2 2 1 QueF-like protein Pribosyltran PF00156.22 AEO64612.1 - 2.9e-19 68.9 0.0 5.8e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.18 AEO64612.1 - 2.5e-12 46.4 9.8 2.5e-12 46.4 6.8 2.2 2 0 0 2 2 2 1 FAD binding domain P-mevalo_kinase PF04275.9 AEO64612.1 - 4.2e-07 29.6 0.0 6.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Phosphomevalonate kinase BBE PF08031.7 AEO64612.1 - 1.2e-05 25.0 0.0 2.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like UPRTase PF14681.1 AEO64612.1 - 3.8e-05 22.9 0.0 6.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_22 PF13401.1 AEO64612.1 - 0.00014 22.0 0.0 0.0099 16.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Methyltransf_23 PF13489.1 AEO64612.1 - 0.00024 20.8 0.0 0.0006 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TRAPPC10 PF12584.3 AEO64612.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 adh_short PF00106.20 AEO64613.1 - 6.8e-10 39.1 0.1 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO64613.1 - 6.4e-07 29.2 0.0 1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 AEO64613.1 - 0.0029 16.5 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Aldedh PF00171.17 AEO64614.1 - 2.1e-135 451.6 0.0 2.6e-135 451.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 AEO64614.1 - 0.033 12.9 0.0 0.069 11.8 0.0 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) APH PF01636.18 AEO64615.1 - 6.9e-13 48.8 1.3 6.9e-13 48.8 0.9 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family APH PF01636.18 AEO64616.1 - 4.8e-20 72.3 0.3 8.2e-20 71.5 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO64616.1 - 6e-06 25.9 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 AEO64616.1 - 0.0013 18.1 0.0 0.69 9.2 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Pkinase_Tyr PF07714.12 AEO64616.1 - 0.0029 16.7 0.0 0.0045 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4542 PF15075.1 AEO64617.1 - 0.045 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) DUF1996 PF09362.5 AEO64618.1 - 8.2e-86 287.4 3.4 1.1e-85 287.1 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Gly_transf_sug PF04488.10 AEO64619.1 - 2.1e-06 28.0 0.0 6.7e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 AEO64619.1 - 0.0086 14.6 0.0 0.014 13.9 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain COesterase PF00135.23 AEO64622.1 - 6.7e-77 259.4 0.0 3.1e-69 234.1 0.0 2.0 1 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO64622.1 - 4.8e-08 32.8 0.2 9.9e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 AEO64622.1 - 0.00034 19.9 0.0 0.00077 18.7 0.0 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 AEO64622.1 - 0.0019 17.9 2.1 0.0024 17.6 0.4 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO64622.1 - 0.0088 15.2 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Gly-zipper_OmpA PF13436.1 AEO64623.1 - 0.23 11.1 4.4 0.36 10.5 3.1 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain SH3_3 PF08239.6 AEO64624.1 - 7.3e-05 22.8 0.6 0.00018 21.5 0.1 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_4 PF06347.8 AEO64624.1 - 0.0039 16.6 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain NLPC_P60 PF00877.14 AEO64624.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 NlpC/P60 family HET PF06985.6 AEO64625.1 - 6.9e-22 78.1 0.2 2.3e-21 76.3 0.1 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 AEO64626.1 - 8.3e-06 25.1 0.0 2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 AEO64627.1 - 1.5e-05 24.2 0.0 0.00013 21.2 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO64627.1 - 0.0029 16.7 0.0 0.18 10.8 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase IstB_IS21_ATP PF08483.6 AEO64629.1 - 0.02 14.5 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding N-terminal DUF4064 PF13273.1 AEO64630.1 - 0.011 15.8 0.9 5.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) CAP59_mtransfer PF11735.3 AEO64631.1 - 2.1e-63 213.7 0.0 2.7e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Methyltransf_2 PF00891.13 AEO64633.1 - 1.5e-27 96.3 0.1 2.7e-27 95.5 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Glyco_transf_25 PF01755.12 AEO64634.1 - 4.6e-11 42.7 0.0 4.4e-10 39.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) HET PF06985.6 AEO64635.1 - 8.8e-22 77.7 4.7 2.1e-18 66.8 0.5 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MIT PF04212.13 AEO64636.1 - 3.2e-10 39.7 0.8 8.1e-10 38.4 0.5 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain GTP_EFTU PF00009.22 AEO64637.1 - 8.4e-47 159.0 0.0 1.4e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 AEO64637.1 - 2.7e-38 130.1 5.2 4.4e-38 129.4 3.6 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 AEO64637.1 - 5.1e-19 67.9 0.0 1e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AEO64637.1 - 1.9e-06 27.8 0.3 4.2e-06 26.7 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 AEO64637.1 - 1.2e-05 25.0 0.0 8.6e-05 22.3 0.0 2.4 2 1 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 AEO64637.1 - 0.00039 20.3 0.0 0.00095 19.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 AEO64637.1 - 0.0036 16.6 0.0 0.01 15.2 0.0 1.7 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 AEO64637.1 - 0.11 11.7 0.0 0.26 10.4 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Glyco_hydro_10 PF00331.15 AEO64638.1 - 6.3e-104 347.4 0.4 7.2e-104 347.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase-like PF12876.2 AEO64638.1 - 0.042 14.2 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 Sugar-binding cellulase-like DUF4339 PF14237.1 AEO64638.1 - 0.053 13.1 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) Phage_holin PF04688.8 AEO64639.1 - 0.008 15.6 1.8 0.045 13.2 0.1 2.5 2 0 0 2 2 2 1 Phage lysis protein, holin Fungal_trans PF04082.13 AEO64640.1 - 2e-16 59.6 0.2 3.5e-16 58.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO64640.1 - 5.6e-08 32.5 8.5 1.1e-07 31.6 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 AEO64641.1 - 3.5e-24 85.3 0.0 4.3e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO64641.1 - 6.2e-17 62.1 1.8 1e-16 61.5 1.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO64641.1 - 5e-05 22.8 0.0 0.0002 20.8 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO64641.1 - 0.011 14.7 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein NAD_binding_3 PF03447.11 AEO64641.1 - 0.015 15.7 0.3 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 AEO64641.1 - 0.025 13.4 0.1 0.042 12.7 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Saccharop_dh PF03435.13 AEO64641.1 - 0.036 13.0 0.2 0.062 12.2 0.1 1.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase HHH_5 PF14520.1 AEO64641.1 - 0.064 13.4 2.1 16 5.7 0.8 2.9 2 2 0 2 2 2 0 Helix-hairpin-helix domain DapB_N PF01113.15 AEO64641.1 - 0.079 12.8 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Colicin_Ia PF11504.3 AEO64642.1 - 0.024 14.5 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Colicin Ia MFS_1 PF07690.11 AEO64644.1 - 1.1e-28 99.9 71.5 2.1e-21 76.0 31.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO64644.1 - 0.00013 20.5 26.3 0.0013 17.1 7.1 2.8 1 1 1 2 2 2 2 MFS/sugar transport protein DUF1228 PF06779.9 AEO64644.1 - 0.00022 21.1 15.5 0.011 15.6 0.5 4.0 4 1 0 4 4 4 3 Protein of unknown function (DUF1228) Fungal_trans_2 PF11951.3 AEO64645.1 - 2e-42 145.1 2.4 2.8e-42 144.6 1.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 AEO64646.1 - 2.1e-13 50.5 0.0 1.2e-12 48.0 0.0 2.2 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO64646.1 - 0.00029 20.6 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO64646.1 - 0.0008 19.1 0.0 0.0024 17.5 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 AEO64646.1 - 0.0014 18.0 0.0 0.057 12.8 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO64646.1 - 0.012 14.5 0.0 0.098 11.5 0.0 2.2 2 1 0 2 2 2 0 Male sterility protein zf-C2H2 PF00096.21 AEO64647.1 - 7.6e-09 35.4 14.2 0.0001 22.4 0.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO64647.1 - 7.7e-08 32.1 15.2 9.9e-05 22.4 0.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO64647.1 - 0.0036 17.4 2.2 0.0062 16.6 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 AEO64647.1 - 0.0089 16.2 19.8 0.6 10.4 1.6 4.6 4 1 0 4 4 4 3 Zinc-finger double domain zf-H2C2_5 PF13909.1 AEO64647.1 - 0.03 14.5 0.0 0.03 14.5 0.0 3.4 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2HC PF01530.13 AEO64647.1 - 0.36 10.5 3.0 0.55 9.9 0.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2HC type zf-BED PF02892.10 AEO64647.1 - 0.82 9.4 13.4 0.92 9.3 0.2 3.4 3 0 0 3 3 3 0 BED zinc finger Methyltransf_23 PF13489.1 AEO64649.1 - 9.1e-11 41.7 0.0 1.5e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO64649.1 - 1.4e-10 41.7 0.0 2.6e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO64649.1 - 2.7e-09 36.7 0.0 3.5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO64649.1 - 1.1e-08 35.4 0.0 2.1e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO64649.1 - 4.9e-07 30.1 0.0 9.3e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO64649.1 - 6.9e-07 29.3 0.0 1.4e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO64649.1 - 1.1e-06 28.9 0.0 1.8e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 AEO64649.1 - 0.00016 20.9 0.0 0.00023 20.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 AEO64649.1 - 0.00029 20.2 0.0 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 AEO64649.1 - 0.0025 17.8 0.0 0.025 14.5 0.0 2.0 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 AEO64649.1 - 0.0081 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AEO64649.1 - 0.038 13.0 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MFS_1 PF07690.11 AEO64651.1 - 1.5e-30 106.1 27.3 2.2e-30 105.6 18.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.8 AEO64652.1 - 6e-77 258.9 0.4 7e-77 258.7 0.3 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Chorismate_bind PF00425.13 AEO64654.1 - 1.8e-81 273.2 0.0 4.9e-80 268.5 0.0 2.6 2 1 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 AEO64654.1 - 1.5e-32 112.5 0.1 8.4e-28 97.1 0.0 3.2 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region Bac_luciferase PF00296.15 AEO64655.1 - 1.4e-23 83.5 4.3 1.8e-23 83.1 3.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 AEO64656.1 - 2.5e-08 33.0 35.9 9.7e-08 31.1 24.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 AEO64656.1 - 9.1e-06 25.2 4.3 9.1e-06 25.2 3.0 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Pyr_redox_3 PF13738.1 AEO64657.1 - 2.3e-20 73.5 0.0 5.5e-20 72.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AEO64657.1 - 2e-11 42.8 0.0 4.9e-11 41.5 0.0 1.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 AEO64657.1 - 2.4e-08 33.8 0.0 1.8e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 AEO64657.1 - 2.3e-06 26.7 0.1 7.9e-06 25.0 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 AEO64657.1 - 0.0021 17.9 0.0 0.0077 16.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO64657.1 - 0.0026 17.5 0.1 3.2 7.5 0.0 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 AEO64657.1 - 0.0083 15.0 0.0 0.22 10.3 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Podoplanin PF05808.6 AEO64659.1 - 0.045 13.3 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Podoplanin Gly-zipper_YMGG PF13441.1 AEO64659.1 - 0.051 13.0 0.8 0.17 11.4 0.5 1.9 1 0 0 1 1 1 0 YMGG-like Gly-zipper BTB PF00651.26 AEO64660.1 - 0.00018 21.4 0.0 0.025 14.5 0.0 2.5 2 1 0 2 2 2 2 BTB/POZ domain COesterase PF00135.23 AEO64661.1 - 1.4e-99 334.2 0.0 1.2e-91 308.0 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO64661.1 - 1.7e-13 50.6 0.1 3.4e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO64661.1 - 2.6e-05 23.9 0.1 4.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_62 PF03664.8 AEO64662.1 - 1.6e-150 499.6 9.7 1.9e-150 499.4 6.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Nucleoplasmin PF03066.10 AEO64665.1 - 0.0043 16.5 6.6 0.0067 15.9 4.6 1.3 1 0 0 1 1 1 1 Nucleoplasmin TRAP_alpha PF03896.11 AEO64665.1 - 0.052 12.5 0.3 0.086 11.8 0.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 AEO64665.1 - 0.099 11.1 3.2 0.13 10.7 2.2 1.2 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 AEO64665.1 - 0.23 9.2 1.7 0.32 8.8 1.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2722 PF10846.3 AEO64665.1 - 0.27 10.1 1.1 0.41 9.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CDC45 PF02724.9 AEO64665.1 - 0.28 9.1 2.6 0.4 8.6 1.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 AEO64665.1 - 1.6 6.5 9.7 2.3 6.0 6.7 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_RNA_Pol_19 PF05320.7 AEO64665.1 - 1.8 8.3 5.7 3.1 7.5 3.9 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit RXT2_N PF08595.6 AEO64665.1 - 5.8 6.6 6.7 10 5.9 4.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Glyco_hydro_45 PF02015.11 AEO64667.1 - 4.4e-94 314.2 20.7 4.4e-94 314.2 14.3 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 45 CBM_1 PF00734.13 AEO64667.1 - 1.7e-14 53.1 10.0 1.7e-14 53.1 6.9 3.2 4 0 0 4 4 4 1 Fungal cellulose binding domain RNA_pol_Rpb2_6 PF00562.23 AEO64668.1 - 5.7e-125 417.0 0.0 9.9e-125 416.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AEO64668.1 - 4.1e-54 182.6 0.0 6.6e-54 181.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 AEO64668.1 - 5.3e-46 156.4 0.0 1.2e-45 155.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 AEO64668.1 - 2e-30 104.8 0.0 4.9e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 AEO64668.1 - 3.1e-24 84.6 0.0 9e-24 83.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 AEO64668.1 - 6.8e-23 80.1 0.1 1.9e-22 78.7 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 AEO64668.1 - 3.9e-20 71.4 0.2 1e-19 70.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 V-ATPase_G PF03179.10 AEO64670.1 - 5.5e-32 110.1 16.3 6.2e-32 110.0 11.3 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF87 PF01935.12 AEO64670.1 - 0.11 12.3 0.9 0.13 12.0 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF2203 PF09969.4 AEO64670.1 - 0.19 11.9 4.3 0.24 11.6 3.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) TPR_16 PF13432.1 AEO64670.1 - 0.2 12.3 6.1 0.36 11.5 4.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Vfa1 PF08432.5 AEO64670.1 - 0.21 11.6 8.1 0.24 11.4 5.6 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HrpE PF06188.7 AEO64670.1 - 0.35 10.5 11.2 2.2 7.9 1.4 2.0 1 1 1 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF3552 PF12072.3 AEO64670.1 - 0.59 9.3 21.0 0.079 12.1 9.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Asp-B-Hydro_N PF05279.6 AEO64670.1 - 0.61 9.8 10.3 0.69 9.7 7.1 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ATP11 PF06644.6 AEO64670.1 - 0.63 9.4 6.2 0.71 9.3 4.3 1.0 1 0 0 1 1 1 0 ATP11 protein ATP-synt_B PF00430.13 AEO64670.1 - 0.64 9.8 21.8 0.044 13.5 7.1 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) OmpH PF03938.9 AEO64670.1 - 0.95 9.3 11.9 1.2 9.1 8.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Potyvirid-P3 PF13608.1 AEO64670.1 - 1.9 7.5 5.1 2.2 7.3 3.5 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein RRF PF01765.14 AEO64670.1 - 7.2 6.0 11.1 9.3 5.6 7.7 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Atg14 PF10186.4 AEO64670.1 - 7.4 5.4 8.7 8.3 5.2 6.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 vATP-synt_E PF01991.13 AEO64670.1 - 9.8 5.3 20.6 4.6 6.4 8.3 2.1 1 1 0 2 2 2 0 ATP synthase (E/31 kDa) subunit CTNNBL PF08216.6 AEO64671.1 - 1.9e-31 107.8 0.0 2.1e-30 104.4 0.0 2.7 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Ank_2 PF12796.2 AEO64672.1 - 2e-38 130.5 0.5 1e-15 57.8 0.0 4.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 AEO64672.1 - 1.6e-32 109.6 3.7 0.00021 20.9 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.1 AEO64672.1 - 7.2e-26 87.6 1.2 0.032 14.4 0.0 9.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 AEO64672.1 - 5.4e-22 77.7 0.0 0.023 15.1 0.0 7.1 1 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO64672.1 - 1.9e-16 59.7 6.5 0.037 14.2 0.0 8.0 4 2 4 8 8 8 6 Ankyrin repeats (many copies) NACHT PF05729.7 AEO64672.1 - 3.2e-08 33.3 0.0 8e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 AEO64672.1 - 0.00036 20.5 0.2 0.00036 20.5 0.1 3.4 3 2 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 AEO64672.1 - 0.0055 16.8 0.0 0.025 14.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 AEO64672.1 - 0.041 12.8 0.6 0.45 9.4 0.1 2.3 1 1 0 2 2 2 0 KAP family P-loop domain AAA_19 PF13245.1 AEO64672.1 - 0.049 13.3 0.0 0.17 11.6 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Shigella_OspC PF06128.6 AEO64672.1 - 0.21 11.0 0.0 4.1 6.8 0.0 2.5 2 1 0 3 3 3 0 Shigella flexneri OspC protein DUF4149 PF13664.1 AEO64673.1 - 8.5e-19 67.4 1.6 8.6e-19 67.4 0.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) MFS_1 PF07690.11 AEO64674.1 - 2.2e-14 52.9 30.8 2.2e-14 52.9 21.3 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily FAD_binding_4 PF01565.18 AEO64675.1 - 4.1e-16 58.7 2.0 7.3e-16 57.9 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO64675.1 - 4.3e-05 23.3 0.2 8.8e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF1996 PF09362.5 AEO64676.1 - 6.3e-88 294.4 1.7 7.8e-88 294.0 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF3712 PF12505.3 AEO64677.1 - 0.026 14.5 0.1 0.033 14.2 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3712) MFS_1 PF07690.11 AEO64679.1 - 9.5e-36 123.2 50.8 3.9e-34 117.9 34.1 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO64679.1 - 1.1e-10 40.4 12.6 1.7e-10 39.7 8.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 AEO64679.1 - 0.00019 20.1 14.8 0.00019 20.1 10.3 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter NmrA PF05368.8 AEO64680.1 - 5.7e-37 127.2 0.1 7.4e-37 126.8 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO64680.1 - 2.9e-11 43.6 1.0 4.8e-11 42.9 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 AEO64680.1 - 4.4e-06 25.6 0.0 5.9e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AEO64680.1 - 5.9e-05 22.6 0.5 0.00011 21.7 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 AEO64680.1 - 0.0012 19.0 0.2 0.0047 17.2 0.1 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 AEO64680.1 - 0.0063 16.4 0.6 0.0063 16.4 0.4 2.2 2 0 0 2 2 2 1 short chain dehydrogenase DapB_N PF01113.15 AEO64680.1 - 0.018 14.9 0.2 0.035 14.0 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.15 AEO64680.1 - 0.043 13.9 0.1 0.073 13.1 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KR PF08659.5 AEO64680.1 - 0.07 12.7 1.7 0.12 12.0 0.1 2.0 2 0 0 2 2 2 0 KR domain RmlD_sub_bind PF04321.12 AEO64680.1 - 0.086 11.7 3.2 0.032 13.1 0.5 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain Peptidase_S28 PF05577.7 AEO64682.1 - 1.7e-47 161.9 1.9 6.8e-38 130.3 0.1 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 AEO64682.1 - 5e-06 26.5 0.3 1e-05 25.5 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 AEO64682.1 - 0.00063 19.2 0.5 0.0013 18.2 0.4 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 AEO64682.1 - 0.013 14.7 0.1 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO64682.1 - 0.031 14.0 0.1 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family TauD PF02668.11 AEO64683.1 - 1.3e-31 110.1 0.1 1.8e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 AEO64683.1 - 0.023 13.5 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 CsiD AA_permease_2 PF13520.1 AEO64684.1 - 3.5e-72 243.2 34.4 4.3e-72 242.9 23.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO64684.1 - 5.2e-16 58.0 31.4 7.7e-16 57.4 21.8 1.2 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 AEO64686.1 - 1.7e-39 135.5 41.9 1.7e-39 135.5 29.0 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO64686.1 - 1.3e-15 56.9 13.0 1.3e-15 56.9 9.0 2.0 3 0 0 3 3 3 1 Sugar (and other) transporter ComA PF02679.10 AEO64687.1 - 1.3e-71 240.4 0.0 1.6e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) Peptidase_M10 PF00413.19 AEO64688.1 - 0.0028 17.4 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.1 AEO64688.1 - 0.0029 17.6 0.0 0.0042 17.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.8 AEO64688.1 - 0.0037 16.8 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin PF01421.14 AEO64688.1 - 0.0046 16.5 0.0 0.0063 16.1 0.0 1.1 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.1 AEO64688.1 - 0.0046 17.4 0.1 0.0091 16.5 0.1 1.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 AEO64688.1 - 0.0098 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 AEO64688.1 - 0.013 14.7 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_5 PF13688.1 AEO64688.1 - 0.015 15.1 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.4 AEO64688.1 - 0.23 10.3 0.4 0.31 9.8 0.3 1.1 1 0 0 1 1 1 0 Peptidase M66 Peptidase_MA_2 PF13485.1 AEO64688.1 - 0.28 11.2 2.5 0.93 9.5 0.4 2.1 1 1 1 2 2 2 0 Peptidase MA superfamily SLT PF01464.15 AEO64690.1 - 4.8e-08 32.5 0.3 1.4e-07 31.0 0.2 1.6 1 1 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.1 AEO64690.1 - 0.00034 20.1 2.8 0.00072 19.0 1.9 1.4 1 1 0 1 1 1 1 Lysozyme-like CAF-1_p150 PF11600.3 AEO64693.1 - 0.0058 16.0 24.3 0.0088 15.4 16.8 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2217 PF10265.4 AEO64693.1 - 0.8 8.3 4.3 1.1 7.9 3.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Corona_nucleoca PF00937.13 AEO64693.1 - 1.5 7.6 13.5 2.5 6.9 9.4 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Pap_E4 PF02711.9 AEO64693.1 - 5.9 7.7 8.2 5 8.0 0.9 2.6 2 0 0 2 2 2 0 E4 protein IDO PF01231.13 AEO64694.1 - 7.9e-170 564.8 0.0 9.1e-170 564.6 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UEV PF05743.8 AEO64695.1 - 6e-39 132.4 0.1 8.8e-39 131.9 0.1 1.2 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 AEO64695.1 - 2.7e-24 84.5 2.0 2.1e-23 81.7 0.0 2.4 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.21 AEO64695.1 - 0.002 17.5 0.2 0.0037 16.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF566 PF04484.7 AEO64697.1 - 6.1 6.2 7.6 7.3 5.9 5.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) STE2 PF02116.10 AEO64698.1 - 8.8e-33 113.5 14.0 9.9e-33 113.3 9.7 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR UPF0182 PF03699.8 AEO64698.1 - 8.7 4.1 7.5 14 3.5 5.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Aldo_ket_red PF00248.16 AEO64699.1 - 9.3e-53 178.8 0.0 1e-52 178.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GXWXG PF14231.1 AEO64699.1 - 0.028 14.0 0.0 0.49 10.0 0.0 2.3 2 0 0 2 2 2 0 GXWXG protein CN_hydrolase PF00795.17 AEO64700.1 - 3.1e-25 88.5 0.0 7.7e-25 87.3 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Lipase_GDSL_2 PF13472.1 AEO64701.1 - 1.3e-13 51.4 0.1 1.6e-13 51.1 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO64701.1 - 2.9e-10 40.3 0.1 1.3e-09 38.2 0.1 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Herpes_UL92 PF03048.9 AEO64701.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 UL92 family Abhydrolase_4 PF08386.5 AEO64702.1 - 7.3e-19 67.5 0.1 3.1e-18 65.5 0.0 2.1 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 AEO64702.1 - 0.014 14.9 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Fungal_trans PF04082.13 AEO64704.1 - 1.6e-23 82.9 0.0 2.2e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MR_MLE_C PF13378.1 AEO64705.1 - 9.6e-22 77.0 0.0 4.2e-21 75.0 0.0 1.9 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 AEO64705.1 - 1.3e-13 51.2 0.0 4e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 AEO64705.1 - 0.00028 20.8 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short PF00106.20 AEO64706.1 - 4.8e-24 85.1 1.5 6.2e-24 84.7 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO64706.1 - 1.4e-19 70.8 0.0 1.7e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO64706.1 - 2.9e-09 36.8 0.3 4.2e-09 36.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 AEO64706.1 - 0.032 13.9 0.2 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GST_N PF02798.15 AEO64707.1 - 6.6e-12 45.4 0.1 3.8e-11 42.9 0.0 2.3 4 0 0 4 4 4 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 AEO64707.1 - 1.6e-11 44.2 0.0 3.1e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO64707.1 - 4.8e-10 39.3 0.0 1.4e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 AEO64707.1 - 7e-10 38.7 0.0 1.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 AEO64707.1 - 1.7e-08 34.1 0.5 3.1e-08 33.3 0.3 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AEO64707.1 - 6.2e-07 29.8 0.4 1e-06 29.1 0.3 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4531 PF15041.1 AEO64707.1 - 0.071 12.8 0.1 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4531) bZIP_1 PF00170.16 AEO64709.1 - 0.00079 19.3 6.1 0.00079 19.3 4.2 3.7 4 0 0 4 4 3 1 bZIP transcription factor Tropomyosin_1 PF12718.2 AEO64709.1 - 0.00098 18.9 33.8 0.0015 18.3 12.1 2.8 1 1 2 3 3 3 2 Tropomyosin like DUF3584 PF12128.3 AEO64709.1 - 0.0017 15.7 20.7 0.0027 15.1 14.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF904 PF06005.7 AEO64709.1 - 0.012 15.9 7.3 0.012 15.9 5.1 3.6 3 1 0 3 3 2 0 Protein of unknown function (DUF904) ATG16 PF08614.6 AEO64709.1 - 0.046 13.5 32.0 0.066 13.0 10.5 3.5 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Striatin PF08232.7 AEO64709.1 - 0.13 12.5 27.4 0.021 15.1 8.6 2.8 1 1 1 2 2 2 0 Striatin family IncA PF04156.9 AEO64709.1 - 0.15 11.6 36.2 1.2e+03 -1.1 25.1 3.0 1 1 0 1 1 1 0 IncA protein DUF972 PF06156.8 AEO64709.1 - 0.23 11.8 20.2 0.39 11.0 4.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 AEO64709.1 - 0.77 9.5 5.9 0.3 10.8 1.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4618 PF15397.1 AEO64709.1 - 0.83 8.9 22.8 0.32 10.3 13.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DivIVA PF05103.8 AEO64709.1 - 0.97 9.4 29.7 0.86 9.6 4.6 3.2 2 1 1 3 3 3 0 DivIVA protein AAA_13 PF13166.1 AEO64709.1 - 3.1 6.1 17.2 0.69 8.2 3.9 2.1 1 1 1 2 2 2 0 AAA domain Phage_GP20 PF06810.6 AEO64709.1 - 4 6.8 15.8 0.71 9.3 0.9 3.0 1 1 0 2 2 2 0 Phage minor structural protein GP20 Fmp27_WPPW PF10359.4 AEO64709.1 - 4.4 5.6 20.8 3.9 5.7 6.0 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain HALZ PF02183.13 AEO64709.1 - 4.8 6.9 14.0 9.1 6.0 4.0 3.8 3 1 1 4 4 4 0 Homeobox associated leucine zipper ADIP PF11559.3 AEO64709.1 - 4.8 7.0 31.7 0.048 13.5 7.3 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 AEO64709.1 - 6 6.7 29.6 0.23 11.2 8.2 3.2 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 AEO64709.1 - 6.2 6.3 23.7 0.046 13.2 3.8 3.6 1 1 0 2 2 2 0 Septum formation initiator FlxA PF14282.1 AEO64709.1 - 7.6 6.5 17.4 0.17 11.8 2.4 3.2 2 1 1 3 3 3 0 FlxA-like protein GTP_EFTU_D4 PF14578.1 AEO64710.1 - 9e-10 38.0 11.1 5.3 6.7 0.0 8.3 9 0 0 9 9 9 6 Elongation factor Tu domain 4 Antimicrobial_2 PF08023.7 AEO64710.1 - 0.2 11.9 18.8 50 4.3 0.0 9.0 10 0 0 10 10 10 0 Frog antimicrobial peptide RAB3GAP2_N PF14655.1 AEO64710.1 - 0.29 10.0 1.8 0.24 10.3 0.2 1.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus NACHT PF05729.7 AEO64711.1 - 6.5e-09 35.6 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 AEO64711.1 - 1.5e-05 25.0 0.0 5e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 AEO64711.1 - 0.0043 16.9 0.0 0.054 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 AEO64711.1 - 0.024 13.6 0.0 0.044 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 AEO64711.1 - 0.038 14.1 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AEO64711.1 - 0.089 13.6 0.5 0.55 11.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 AEO64711.1 - 0.14 12.4 0.0 0.43 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 AEO64711.1 - 0.24 10.2 0.0 0.48 9.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Hce2 PF14856.1 AEO64712.1 - 3.4e-12 46.1 0.0 4.5e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Toprim_2 PF13155.1 AEO64712.1 - 0.032 14.5 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 Toprim-like Methyltransf_11 PF08241.7 AEO64713.1 - 1.1e-09 38.6 0.0 2.1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO64713.1 - 3.1e-09 37.3 0.4 5.6e-09 36.5 0.3 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO64713.1 - 1.6e-07 31.3 1.8 1.6e-07 31.3 1.2 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO64713.1 - 6.7e-07 29.0 0.0 3.6e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO64713.1 - 9e-06 25.4 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO64713.1 - 8.8e-05 22.9 0.1 0.00035 20.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO64713.1 - 0.00026 21.3 0.0 0.00049 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 AEO64713.1 - 0.0013 18.6 0.2 0.0028 17.5 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Tyrosinase PF00264.15 AEO64714.1 - 8.1e-40 137.3 0.0 1.4e-39 136.5 0.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase HLH PF00010.21 AEO64715.1 - 0.0035 17.0 0.0 0.013 15.1 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain adh_short PF00106.20 AEO64716.1 - 5.2e-27 94.7 2.0 7.1e-27 94.3 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO64716.1 - 5.6e-17 62.3 0.0 7.8e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO64716.1 - 6.8e-08 32.3 0.8 9.9e-08 31.8 0.6 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 AEO64716.1 - 3.4e-07 29.7 0.0 0.0093 15.1 0.0 3.0 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 AEO64716.1 - 7.2e-05 22.8 0.3 0.00014 21.9 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO64716.1 - 0.00045 19.7 0.1 0.0046 16.4 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 AEO64716.1 - 0.0068 15.6 0.0 0.017 14.3 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family PAE PF03283.8 AEO64716.1 - 0.01 14.5 0.1 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 Pectinacetylesterase RmlD_sub_bind PF04321.12 AEO64716.1 - 0.014 14.2 0.1 0.3 9.9 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 AEO64716.1 - 0.037 13.8 0.1 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 AEO64716.1 - 0.043 13.4 0.3 0.084 12.4 0.0 1.5 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Methyltransf_11 PF08241.7 AEO64718.1 - 6.9e-26 90.5 0.0 1.2e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO64718.1 - 1e-25 90.0 0.0 1.5e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO64718.1 - 6.4e-18 65.0 0.0 1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO64718.1 - 4.8e-17 61.8 0.0 7.1e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 AEO64718.1 - 4e-15 55.8 0.0 5.7e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO64718.1 - 4e-15 56.3 0.1 9.4e-15 55.1 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO64718.1 - 1.6e-14 54.1 0.0 3.6e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO64718.1 - 2e-12 46.8 0.0 3.1e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 AEO64718.1 - 8.1e-12 45.2 2.1 1.6e-11 44.2 1.5 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AEO64718.1 - 2.6e-07 30.3 0.0 3.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 AEO64718.1 - 6.2e-07 28.9 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.13 AEO64718.1 - 1.7e-06 27.4 0.0 0.009 15.3 0.0 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_29 PF03141.11 AEO64718.1 - 5.8e-06 24.9 0.4 1.4e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 AEO64718.1 - 3.1e-05 23.1 0.0 4.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 AEO64718.1 - 4.6e-05 22.5 0.0 8.3e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.7 AEO64718.1 - 0.00011 21.7 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) DREV PF05219.7 AEO64718.1 - 0.00013 20.9 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase GCD14 PF08704.5 AEO64718.1 - 0.00016 21.2 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.8 AEO64718.1 - 0.00026 20.2 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 AEO64718.1 - 0.00075 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.6 AEO64718.1 - 0.0044 15.7 0.0 0.0084 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 AEO64718.1 - 0.0051 16.5 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 AEO64718.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.10 AEO64718.1 - 0.074 12.6 0.0 0.16 11.6 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase CMAS PF02353.15 AEO64718.1 - 0.14 11.2 0.0 0.23 10.4 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Pkinase PF00069.20 AEO64721.1 - 1.8e-15 56.8 0.0 2.8e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO64721.1 - 3.6e-12 45.9 0.0 9.8e-12 44.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO64721.1 - 0.011 14.7 0.0 0.03 13.2 0.0 1.7 1 1 0 1 1 1 0 Kinase-like RRM_1 PF00076.17 AEO64722.1 - 1.1e-44 149.9 0.1 2.4e-15 55.9 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO64722.1 - 1.5e-43 146.5 0.1 5e-15 55.2 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO64722.1 - 7.4e-23 80.1 0.2 3.7e-08 33.1 0.0 4.9 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO64722.1 - 2.5e-08 33.5 0.0 0.0006 19.5 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 AEO64722.1 - 0.026 14.3 0.1 0.38 10.6 0.0 3.0 3 0 0 3 3 3 0 RNA binding motif Lsm_interact PF05391.6 AEO64722.1 - 0.027 13.8 0.0 0.079 12.4 0.0 1.8 1 0 0 1 1 1 0 Lsm interaction motif adh_short PF00106.20 AEO64725.1 - 2e-17 63.5 13.2 1.1e-16 61.1 9.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO64725.1 - 1.6e-06 27.9 5.3 2.7e-06 27.1 3.7 1.5 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 AEO64725.1 - 0.13 12.0 2.0 0.68 9.7 1.2 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fructosamin_kin PF03881.9 AEO64727.1 - 5.6e-29 101.0 0.0 6.7e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 AEO64727.1 - 0.023 14.4 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family PGAP1 PF07819.8 AEO64728.1 - 1.8e-06 27.6 0.0 1.5e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 AEO64728.1 - 3e-06 27.2 0.0 7.6e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 AEO64728.1 - 0.00038 19.8 0.0 0.0014 17.9 0.0 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 AEO64728.1 - 0.0031 17.2 0.0 0.016 14.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 AEO64728.1 - 0.021 13.7 0.0 0.11 11.4 0.0 1.8 1 1 1 2 2 2 0 Lecithin:cholesterol acyltransferase Abhydrolase_2 PF02230.11 AEO64728.1 - 0.16 11.4 0.0 1.6 8.0 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase MFS_1 PF07690.11 AEO64729.1 - 4.4e-18 65.1 24.6 5.6e-10 38.4 4.4 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO64729.1 - 0.00061 18.4 0.7 0.00061 18.4 0.5 3.5 3 1 1 4 4 4 1 Sugar (and other) transporter MFS_1_like PF12832.2 AEO64729.1 - 0.2 11.4 3.8 0.65 9.8 0.2 3.0 2 1 1 3 3 3 0 MFS_1 like family Glyco_transf_8 PF01501.15 AEO64730.1 - 0.00021 20.7 0.7 0.00052 19.4 0.5 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 AEO64730.1 - 0.0015 17.9 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative DUF4360 PF14273.1 AEO64732.1 - 3.1e-62 209.4 0.4 3.6e-62 209.2 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) HA2 PF04408.18 AEO64734.1 - 3.8e-17 62.1 0.0 1e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AEO64734.1 - 2e-12 46.8 0.1 4.6e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AEO64734.1 - 1.5e-10 40.8 0.0 3.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AEO64734.1 - 1.1e-07 31.9 1.8 2.6e-07 30.8 0.1 2.5 3 0 0 3 3 2 1 AAA domain OB_NTP_bind PF07717.11 AEO64734.1 - 2.2e-06 27.4 0.0 5.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_29 PF13555.1 AEO64734.1 - 0.0014 18.1 0.0 0.0046 16.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 AEO64734.1 - 0.015 15.5 0.0 0.039 14.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 AEO64734.1 - 0.066 12.1 0.0 0.19 10.6 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein KaiC PF06745.8 AEO64734.1 - 0.1 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF258 PF03193.11 AEO64734.1 - 0.15 11.2 0.0 0.39 9.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 AEO64734.1 - 0.33 11.2 0.0 0.33 11.2 0.0 2.7 4 0 0 4 4 4 0 AAA domain DUF3554 PF12074.3 AEO64735.1 - 1.4e-90 304.1 1.9 1.4e-90 304.1 1.3 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF3554) HEAT PF02985.17 AEO64735.1 - 3.2e-30 101.4 41.4 0.057 13.5 0.0 21.9 22 0 0 22 22 21 8 HEAT repeat HEAT_2 PF13646.1 AEO64735.1 - 3.9e-27 94.3 58.5 8.4e-06 25.9 2.4 16.9 12 3 4 16 16 16 10 HEAT repeats HEAT_EZ PF13513.1 AEO64735.1 - 2.4e-21 75.5 77.2 0.0029 18.0 0.0 22.9 18 5 7 26 26 25 8 HEAT-like repeat ParcG PF10274.4 AEO64735.1 - 7.8e-13 48.7 2.0 2.6e-05 24.1 0.0 6.8 6 1 2 8 8 8 2 Parkin co-regulated protein CLASP_N PF12348.3 AEO64735.1 - 2.8e-12 46.5 0.0 0.00024 20.5 0.0 5.9 5 1 1 6 6 6 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 AEO64735.1 - 3e-12 46.7 0.0 22 5.5 0.0 9.8 8 2 2 10 10 9 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 AEO64735.1 - 1.4e-10 41.2 0.5 3.2 7.5 0.1 9.0 8 3 3 11 11 10 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 AEO64735.1 - 6.5e-08 31.3 1.9 0.43 8.8 0.0 7.4 5 2 2 7 7 7 3 Adaptin N terminal region UME PF08064.8 AEO64735.1 - 1.8e-05 24.6 0.0 12 5.8 0.0 6.7 6 1 2 8 8 8 0 UME (NUC010) domain Ipi1_N PF12333.3 AEO64735.1 - 8.1e-05 22.5 0.2 0.057 13.3 0.0 5.1 5 0 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation DUF3535 PF12054.3 AEO64735.1 - 0.00049 18.8 1.8 0.007 15.0 0.0 3.7 5 0 0 5 5 5 1 Domain of unknown function (DUF3535) Cohesin_HEAT PF12765.2 AEO64735.1 - 1.1 9.2 13.3 8.3 6.4 0.0 6.0 7 0 0 7 7 6 0 HEAT repeat associated with sister chromatid cohesion RIX1 PF08167.7 AEO64735.1 - 2.3 7.8 8.6 4.5 6.9 0.2 5.8 8 0 0 8 8 8 0 rRNA processing/ribosome biogenesis Ribosomal_L19e PF01280.15 AEO64736.1 - 3.2e-61 205.4 8.0 3.2e-61 205.4 5.5 2.0 1 1 1 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 AEO64736.1 - 0.031 13.4 0.7 0.032 13.4 0.5 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Atg14 PF10186.4 AEO64736.1 - 1.6 7.5 8.3 2.9 6.7 5.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3043 PF11241.3 AEO64736.1 - 5.5 6.5 13.7 11 5.5 9.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) SHMT PF00464.14 AEO64737.1 - 2.5e-197 655.0 0.0 2.9e-197 654.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 AEO64737.1 - 0.0059 15.7 0.0 0.015 14.4 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Isochorismatase PF00857.15 AEO64738.1 - 8.6e-28 97.4 0.1 3.4e-27 95.4 0.1 2.0 1 1 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.1 AEO64738.1 - 3e-25 89.1 0.0 5.2e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C_3 PF14497.1 AEO64738.1 - 0.0012 19.2 0.0 0.0034 17.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 AEO64738.1 - 2.6 8.0 15.9 8.3 6.3 11.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LRR_4 PF12799.2 AEO64739.1 - 1.4e-16 59.6 0.5 0.00042 19.8 0.1 5.1 2 2 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO64739.1 - 8.1e-14 51.1 1.2 6.2e-07 29.0 0.1 3.8 1 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 AEO64739.1 - 3.9e-09 35.2 1.1 0.13 12.3 0.1 6.0 6 1 0 6 6 6 2 Leucine Rich Repeat Pkinase_Tyr PF07714.12 AEO64739.1 - 1.9e-06 27.1 0.0 0.03 13.4 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase LRR_7 PF13504.1 AEO64739.1 - 2.3e-05 23.8 6.6 2.3 8.7 0.0 5.7 5 0 0 5 5 5 2 Leucine rich repeat Pkinase PF00069.20 AEO64739.1 - 0.00021 20.5 0.0 0.036 13.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.9 AEO64739.1 - 0.024 13.7 0.1 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.1 AEO64739.1 - 0.24 11.5 1.7 51 4.3 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat Bromo_TP PF07524.8 AEO64740.1 - 1e-15 57.2 0.0 1.5e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 AEO64740.1 - 1.4e-12 47.4 1.3 2.3e-06 27.5 0.8 2.9 3 0 0 3 3 3 2 Transcription factor TFIID complex subunit 8 C-term WD40 PF00400.27 AEO64741.1 - 1.5e-62 205.3 25.6 9.2e-12 44.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 AEO64741.1 - 9.4e-06 24.0 4.9 0.059 11.5 0.1 3.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 AEO64741.1 - 0.034 12.4 0.0 3.9 5.6 0.1 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain P12 PF12669.2 AEO64742.1 - 0.022 14.9 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 Virus attachment protein p12 family Chorion_2 PF03964.10 AEO64742.1 - 0.031 14.8 0.1 0.033 14.7 0.0 1.1 1 0 0 1 1 1 0 Chorion family 2 Ketoacyl-synt_2 PF13723.1 AEO64743.1 - 0.031 13.5 0.0 0.8 8.9 0.0 2.2 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain DUF3112 PF11309.3 AEO64744.1 - 3.1e-49 166.8 16.0 1e-47 161.9 5.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) Mucin PF01456.12 AEO64745.1 - 5e-05 23.1 22.7 5e-05 23.1 15.7 2.3 1 1 1 2 2 2 1 Mucin-like glycoprotein SKG6 PF08693.5 AEO64745.1 - 0.051 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PIH1 PF08190.7 AEO64745.1 - 3.1 7.1 7.7 5.1 6.4 5.3 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Tim54 PF11711.3 AEO64745.1 - 3.8 6.0 7.4 6.3 5.2 5.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ribosomal_L22 PF00237.14 AEO64746.1 - 1.1e-15 57.4 0.3 2e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e GnsAB PF08178.6 AEO64746.1 - 0.061 12.9 0.2 0.16 11.6 0.2 1.7 1 0 0 1 1 1 0 GnsA/GnsB family Ribosomal_60s PF00428.14 AEO64746.1 - 0.11 12.9 3.1 0.32 11.4 2.1 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein INT_SG_DDX_CT_C PF15300.1 AEO64746.1 - 0.15 11.5 0.9 1.6 8.2 0.0 2.5 2 1 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus DUF3439 PF11921.3 AEO64746.1 - 0.21 11.3 3.7 0.39 10.4 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CFEM PF05730.6 AEO64748.1 - 5.1e-13 48.6 7.5 9.3e-13 47.8 5.2 1.4 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.5 AEO64748.1 - 0.0072 15.6 0.5 0.0072 15.6 0.3 2.5 3 0 0 3 3 3 1 Transmembrane alpha-helix domain DUF566 PF04484.7 AEO64748.1 - 1.8 7.9 7.8 2.3 7.6 5.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Peptidase_M74 PF03411.8 AEO64750.1 - 0.041 13.0 0.2 0.073 12.2 0.1 1.3 1 1 0 1 1 1 0 Penicillin-insensitive murein endopeptidase NDUFA12 PF05071.11 AEO64750.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 Hydrolase_6 PF13344.1 AEO64751.1 - 2.7e-23 81.7 0.0 5.5e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO64751.1 - 6.6e-11 41.7 0.0 3.3e-10 39.5 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 AEO64751.1 - 0.00079 19.6 0.0 1.2 9.3 0.1 2.8 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase DUF1237 PF06824.6 AEO64752.1 - 1.4e-175 583.9 0.0 1.7e-175 583.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) PHAT PF09246.5 AEO64752.1 - 0.037 13.6 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 PHAT HET PF06985.6 AEO64754.1 - 3.8e-21 75.7 0.0 4.2e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DPM3 PF08285.6 AEO64755.1 - 0.1 12.4 0.5 0.16 11.8 0.3 1.2 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Gemini_mov PF01708.11 AEO64755.1 - 0.35 10.4 2.2 0.41 10.2 0.4 1.9 2 0 0 2 2 2 0 Geminivirus putative movement protein CDC45 PF02724.9 AEO64755.1 - 1.9 6.3 12.8 2.7 5.9 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 AEO64756.1 - 1.6e-55 183.1 8.3 1.9e-09 37.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 AEO64756.1 - 0.0037 16.0 2.0 0.82 8.3 0.3 3.5 1 1 1 2 2 2 2 Nup133 N terminal like Gmad1 PF10647.4 AEO64756.1 - 0.085 12.2 0.5 0.82 9.0 0.1 2.7 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain TRAPP PF04051.11 AEO64757.1 - 1.3e-36 125.4 0.0 1.5e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.1 AEO64757.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) E7 PF00527.13 AEO64758.1 - 3.6 7.8 6.7 0.75 9.9 1.5 2.1 1 1 1 2 2 2 0 E7 protein, Early protein LisH PF08513.6 AEO64759.1 - 0.25 11.1 0.2 0.46 10.3 0.1 1.4 1 0 0 1 1 1 0 LisH Glyco_hydro_16 PF00722.16 AEO64760.1 - 8.1e-16 57.8 0.0 1.7e-15 56.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 AEO64760.1 - 0.00097 17.4 0.1 0.64 8.1 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.4 AEO64760.1 - 0.08 12.4 0.1 0.28 10.6 0.0 1.6 1 1 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) Peptidase_S8 PF00082.17 AEO64762.1 - 4.3e-47 160.6 12.6 5.9e-47 160.1 8.7 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 AEO64762.1 - 3e-12 46.9 0.0 5.2e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 CCSMST1 PF15013.1 AEO64763.1 - 0.03 14.2 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 CCSMST1 family Glycophorin_A PF01102.13 AEO64764.1 - 0.019 14.7 0.1 0.041 13.6 0.1 1.5 1 0 0 1 1 1 0 Glycophorin A DUF1517 PF07466.6 AEO64764.1 - 0.08 11.9 3.6 0.17 10.8 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Syndecan PF01034.15 AEO64764.1 - 0.22 11.2 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DUF3328 PF11807.3 AEO64766.1 - 5.8e-28 98.0 0.0 7.5e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Amidase PF01425.16 AEO64767.1 - 1.4e-52 179.0 0.4 7e-50 170.1 0.3 2.2 2 0 0 2 2 2 2 Amidase p450 PF00067.17 AEO64768.1 - 8.8e-20 70.6 0.0 5.2e-19 68.1 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.19 AEO64769.1 - 4.2e-06 26.6 0.0 6.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO64769.1 - 6.8e-05 22.9 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO64769.1 - 0.11 12.6 0.1 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Aa_trans PF01490.13 AEO64770.1 - 3.7e-67 226.5 23.5 4.4e-67 226.3 16.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Lyase_1 PF00206.15 AEO64771.1 - 5.2e-89 298.5 0.0 6.7e-89 298.1 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 AEO64771.1 - 3.4e-28 97.5 0.1 1.2e-27 95.7 0.1 2.0 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Abhydrolase_6 PF12697.2 AEO64772.1 - 7.2e-10 39.1 6.8 1.1e-08 35.2 4.7 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO64772.1 - 1.7e-08 34.3 0.0 2.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO64772.1 - 2.5e-05 24.0 0.1 0.00027 20.7 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family NifU_N PF01592.11 AEO64774.1 - 1.3e-52 177.0 0.0 1.7e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain DUF3888 PF13027.1 AEO64774.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) UCH PF00443.24 AEO64775.1 - 3.7e-42 144.2 0.0 5.2e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 AEO64775.1 - 9.2e-27 92.9 8.6 4.2e-20 71.6 1.3 3.2 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 AEO64775.1 - 1e-18 66.5 0.4 3.9e-08 32.9 0.1 3.0 3 0 0 3 3 3 2 UBA/TS-N domain UCH_1 PF13423.1 AEO64775.1 - 5e-18 65.5 0.0 3.3e-16 59.6 0.0 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HORMA PF02301.13 AEO64776.1 - 1.9e-41 141.8 0.0 2.3e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 HORMA domain DUF2411 PF10304.4 AEO64776.1 - 0.027 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) Alba PF01918.16 AEO64776.1 - 0.1 12.1 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Alba Epimerase PF01370.16 AEO64777.1 - 4.1e-24 85.3 0.0 4.9e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO64777.1 - 1.3e-12 47.2 0.0 4e-11 42.3 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 AEO64777.1 - 6.4e-12 45.8 0.5 1.9e-11 44.3 0.3 1.8 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 AEO64777.1 - 2.3e-10 39.6 0.0 4.5e-10 38.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 AEO64777.1 - 2.1e-06 27.7 0.3 2e-05 24.5 0.2 2.5 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 AEO64777.1 - 2.4e-05 23.7 0.1 5.2e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 AEO64777.1 - 0.0011 18.7 0.2 0.023 14.3 0.2 2.4 1 1 0 1 1 1 1 KR domain p450 PF00067.17 AEO64778.1 - 3.3e-44 151.1 0.0 1.4e-33 116.1 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 GFA PF04828.9 AEO64779.1 - 1e-17 63.8 0.1 1.4e-17 63.4 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 AEO64779.1 - 0.032 14.0 3.4 1 9.2 2.5 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 AEO64779.1 - 0.47 9.7 0.1 0.47 9.7 0.1 2.5 3 0 0 3 3 3 0 zinc-ribbon domain Syndecan PF01034.15 AEO64780.1 - 0.0079 15.8 0.6 0.017 14.7 0.4 1.4 1 0 0 1 1 1 1 Syndecan domain PAGK PF15284.1 AEO64780.1 - 0.028 14.1 1.2 0.066 12.9 0.9 1.6 1 0 0 1 1 1 0 Phage-encoded virulence factor NfeD PF01957.13 AEO64780.1 - 0.13 12.4 1.5 0.31 11.1 1.0 1.6 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding TRP PF06011.7 AEO64781.1 - 8.7e-145 482.6 34.3 1.1e-144 482.3 23.7 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 AEO64781.1 - 3.5e-40 137.3 0.3 5.4e-40 136.6 0.2 1.3 1 0 0 1 1 1 1 ML-like domain DUF1049 PF06305.6 AEO64781.1 - 0.12 11.8 0.1 0.12 11.8 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) Cauli_VI PF01693.11 AEO64782.1 - 1.5e-33 114.5 4.9 5.7e-17 61.4 0.2 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 AEO64782.1 - 7.6e-30 103.9 0.0 1.6e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 RNase H Aldolase_II PF00596.16 AEO64785.1 - 1.2e-21 77.1 0.2 1.6e-21 76.7 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain HET PF06985.6 AEO64787.1 - 5.5e-36 123.7 0.0 9.4e-36 123.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Rft-1 PF04506.8 AEO64788.1 - 1.4e-88 297.6 0.3 1.8e-88 297.2 0.2 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.12 AEO64788.1 - 5.7e-05 22.5 13.4 0.00011 21.5 5.0 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein DEAD PF00270.24 AEO64789.1 - 9.5e-47 158.6 0.0 5.5e-44 149.6 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO64789.1 - 1.5e-29 101.6 0.1 1.1e-28 98.9 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 AEO64789.1 - 0.043 12.2 0.0 0.043 12.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) FAM60A PF15396.1 AEO64789.1 - 0.16 11.7 13.3 0.34 10.6 9.2 1.7 1 0 0 1 1 1 0 Protein Family FAM60A CMS1 PF14617.1 AEO64789.1 - 0.8 8.7 0.0 0.8 8.7 0.0 3.0 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit MIP-T3 PF10243.4 AEO64789.1 - 2.5 6.4 48.3 3.5 5.9 33.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 AEO64789.1 - 5.3 5.4 27.9 7.5 4.9 19.3 1.1 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 AEO64789.1 - 5.7 5.8 13.3 9.8 5.0 9.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SOBP PF15279.1 AEO64789.1 - 7 6.9 16.1 12 6.1 11.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein K_trans PF02705.11 AEO64790.1 - 4.2e-179 596.3 19.3 4.9e-179 596.1 13.3 1.0 1 0 0 1 1 1 1 K+ potassium transporter adh_short PF00106.20 AEO64791.1 - 2.1e-23 83.0 0.1 2.6e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO64791.1 - 1.1e-14 54.7 0.0 1.5e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO64791.1 - 3.4e-09 36.6 0.0 5.1e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO64791.1 - 1.3e-06 28.5 0.0 2.1e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO64791.1 - 5e-05 22.8 0.0 8e-05 22.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 AEO64791.1 - 0.0045 15.9 0.0 0.0079 15.1 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 AEO64791.1 - 0.0057 16.4 0.2 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2292 PF10055.4 AEO64791.1 - 0.15 11.4 0.3 0.25 10.6 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2292) ADH_N PF08240.7 AEO64792.1 - 1.9e-26 91.9 1.4 3.6e-26 91.0 1.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 AEO64792.1 - 6.7e-08 32.0 0.3 6.7e-08 32.0 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 AEO64792.1 - 1.5e-05 24.5 0.4 0.0095 15.4 0.1 3.0 2 1 0 2 2 2 2 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 AEO64792.1 - 0.027 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PDZ_2 PF13180.1 AEO64792.1 - 0.16 11.9 0.7 0.29 11.0 0.1 1.7 2 0 0 2 2 2 0 PDZ domain HET PF06985.6 AEO64793.1 - 5.6e-05 23.3 0.2 0.027 14.6 0.0 3.1 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) MARVEL PF01284.18 AEO64795.1 - 0.007 16.1 21.3 0.013 15.3 14.8 1.5 1 1 0 1 1 1 1 Membrane-associating domain Ycf9 PF01737.12 AEO64795.1 - 1 8.8 9.3 0.98 8.9 1.8 2.5 2 0 0 2 2 2 0 YCF9 FAD_binding_3 PF01494.14 AEO64796.1 - 2.3e-65 220.9 0.0 3.5e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain EI24 PF07264.6 AEO64797.1 - 0.011 15.1 3.2 0.013 14.9 2.2 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF4131 PF13567.1 AEO64797.1 - 0.11 11.8 1.3 0.16 11.4 0.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) p450 PF00067.17 AEO64799.1 - 5.1e-56 190.1 0.0 7.7e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.9 AEO64799.1 - 7.4e-27 94.5 2.4 1.2e-26 93.8 1.7 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO64799.1 - 2.4e-12 47.0 3.0 1.6e-11 44.4 0.4 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO64799.1 - 7.7e-06 26.1 0.2 0.00072 19.6 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 AEO64799.1 - 3.6e-05 23.9 0.1 0.00011 22.3 0.1 1.9 1 0 0 1 1 1 1 Reductase C-terminal Dodecin PF07311.7 AEO64799.1 - 0.18 11.8 2.1 2.2 8.3 0.1 2.5 2 0 0 2 2 2 0 Dodecin NAD_binding_7 PF13241.1 AEO64799.1 - 0.26 11.5 0.7 6.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 AEO64799.1 - 0.56 9.9 3.7 8 6.2 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Abhydrolase_3 PF07859.8 AEO64801.1 - 5.7e-14 52.1 0.0 6.5e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans PF04082.13 AEO64802.1 - 7.6e-15 54.4 0.0 1.3e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 AEO64803.1 - 2.4e-36 125.2 41.9 2.4e-36 125.2 29.0 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO64803.1 - 3.5e-15 55.5 2.6 3.5e-15 55.5 1.8 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 AEO64803.1 - 0.00036 18.8 7.8 0.00047 18.4 5.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 AEO64803.1 - 0.0015 16.7 7.5 0.002 16.3 5.2 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector adh_short PF00106.20 AEO64804.1 - 6.9e-07 29.3 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO64804.1 - 0.0013 18.5 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO64804.1 - 0.0093 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.17 AEO64805.1 - 5.5e-33 113.3 0.0 1.4e-32 112.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 AEO64805.1 - 4.5e-29 101.6 0.1 3e-23 82.5 0.0 2.7 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 AEO64805.1 - 1.3e-28 100.2 0.0 2.5e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 AEO64805.1 - 2.6e-23 82.2 0.0 4.8e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 AEO64805.1 - 1.2e-13 51.4 0.0 3e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO64805.1 - 2.8e-09 36.9 0.0 1.3e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO64805.1 - 5.3e-09 35.8 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 AEO64805.1 - 8.4e-09 35.5 0.1 2.3e-08 34.1 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 AEO64805.1 - 2.2e-06 27.6 0.1 1.9e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_18 PF12847.2 AEO64805.1 - 3.3e-06 27.6 0.0 1.6e-05 25.4 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO64805.1 - 7.7e-06 26.3 0.0 2.2e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 AEO64805.1 - 3.6e-05 23.3 0.0 8.2e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 AEO64805.1 - 0.00012 21.8 0.0 0.00092 18.9 0.0 2.5 2 0 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.12 AEO64805.1 - 0.0005 19.0 0.0 0.95 8.2 0.0 2.5 2 0 0 2 2 2 2 RmlD substrate binding domain RrnaAD PF00398.15 AEO64805.1 - 0.0019 17.2 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 AEO64805.1 - 0.0031 16.6 0.0 0.014 14.5 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AEO64805.1 - 0.0068 16.4 0.0 0.028 14.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 AEO64805.1 - 0.029 14.0 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 AEO64805.1 - 0.043 12.6 0.0 0.071 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 AEO64805.1 - 0.26 11.1 0.0 0.72 9.7 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Transferase PF02458.10 AEO64806.1 - 1.3e-21 76.5 0.0 1.8e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Transferase family adh_short PF00106.20 AEO64807.1 - 5.9e-19 68.5 2.0 9.2e-19 67.9 1.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO64807.1 - 3.2e-09 36.8 0.2 8e-09 35.6 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 AEO64807.1 - 1.5e-06 28.3 0.2 2.3e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 AEO64807.1 - 1.1e-05 25.1 1.3 0.00013 21.6 1.6 2.3 2 1 0 2 2 2 1 KR domain NmrA PF05368.8 AEO64807.1 - 0.00052 19.3 0.1 0.00085 18.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.12 AEO64807.1 - 0.0028 18.0 0.1 0.0057 17.0 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 AEO64807.1 - 0.021 14.2 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 AEO64807.1 - 0.027 13.3 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.10 AEO64807.1 - 0.066 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF1776 PF08643.5 AEO64807.1 - 0.098 11.7 0.0 0.61 9.1 0.0 1.9 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) PAE PF03283.8 AEO64807.1 - 0.18 10.4 0.1 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase ADH_zinc_N PF00107.21 AEO64808.1 - 8.9e-09 34.9 1.2 1.5e-08 34.2 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO64808.1 - 7.2e-08 32.1 0.0 2.1e-07 30.6 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 AEO64808.1 - 0.091 12.6 0.4 0.17 11.8 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase rve PF00665.21 AEO64809.1 - 0.00015 21.8 0.0 0.00016 21.7 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Cu-oxidase_3 PF07732.10 AEO64812.1 - 7.1e-43 145.0 6.0 7.8e-42 141.7 1.8 3.4 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 AEO64812.1 - 5.9e-33 113.3 5.8 5.3e-32 110.1 0.0 3.0 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 AEO64812.1 - 1.7e-29 102.7 0.0 3.3e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase FUSC PF04632.7 AEO64813.1 - 0.012 14.0 1.6 0.018 13.5 0.0 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family ADH_zinc_N PF00107.21 AEO64814.1 - 1.5e-12 47.2 0.2 3.1e-12 46.1 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO64814.1 - 3.2e-05 23.6 0.0 5.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Tri3 PF07428.6 AEO64815.1 - 0.18 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 FAD_binding_3 PF01494.14 AEO64816.1 - 1.4e-18 67.1 3.3 1.3e-17 63.9 2.3 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO64816.1 - 4.4e-07 29.1 3.0 3.6e-05 22.8 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 AEO64816.1 - 0.00013 21.7 0.3 0.0036 17.0 0.1 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 AEO64816.1 - 0.0011 19.0 1.1 0.0031 17.5 0.1 2.2 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 AEO64816.1 - 0.0018 17.0 1.5 0.27 9.8 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 AEO64816.1 - 0.0056 17.0 1.6 0.016 15.6 1.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO64816.1 - 0.014 15.4 0.4 0.042 13.8 0.3 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 AEO64816.1 - 0.027 13.2 0.0 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.9 AEO64816.1 - 0.028 14.2 1.1 0.077 12.8 0.8 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 AEO64816.1 - 0.054 13.1 0.2 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AEO64816.1 - 0.13 12.6 0.5 0.35 11.3 0.4 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_4 PF01565.18 AEO64817.1 - 1.4e-15 57.0 1.5 2.4e-15 56.2 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO64817.1 - 7.1e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 AEO64818.1 - 1.9e-25 89.3 40.0 1.9e-25 89.3 27.7 3.1 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO64818.1 - 8.6e-06 24.2 11.5 6.2e-05 21.3 7.9 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ferritin_2 PF13668.1 AEO64820.1 - 5.6e-07 29.5 0.4 1e-06 28.7 0.3 1.4 1 0 0 1 1 1 1 Ferritin-like domain MFS_1 PF07690.11 AEO64821.1 - 5e-34 117.5 34.6 5e-34 117.5 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_membrane PF00664.18 AEO64822.1 - 1.1e-58 198.8 30.4 1.6e-30 106.4 5.2 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AEO64822.1 - 1.1e-48 164.9 0.1 2.6e-27 95.7 0.1 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AEO64822.1 - 1.8e-07 31.3 1.3 0.17 11.8 0.6 4.1 2 2 0 2 2 2 1 AAA domain Miro PF08477.8 AEO64822.1 - 2.7e-06 27.8 0.1 0.037 14.5 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein SMC_N PF02463.14 AEO64822.1 - 3.4e-05 23.1 3.6 1.4 8.0 0.0 3.9 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 AEO64822.1 - 0.0001 22.2 0.0 0.35 10.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 AEO64822.1 - 0.00014 22.2 0.1 0.29 11.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 AEO64822.1 - 0.00016 21.1 1.7 0.47 10.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 AEO64822.1 - 0.00023 21.2 0.2 0.034 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 AEO64822.1 - 0.00024 20.5 0.1 0.079 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 AEO64822.1 - 0.0019 17.7 0.0 0.17 11.3 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.1 AEO64822.1 - 0.0032 17.6 0.1 4.3 7.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 AEO64822.1 - 0.0034 16.5 0.5 0.88 8.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 AEO64822.1 - 0.0044 16.1 0.7 0.9 8.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 AEO64822.1 - 0.0071 17.1 0.2 1.8 9.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 AEO64822.1 - 0.018 14.8 4.6 0.042 13.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 AEO64822.1 - 0.03 13.7 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 AEO64822.1 - 0.032 13.6 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.9 AEO64822.1 - 0.059 13.0 0.2 6.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 AEO64822.1 - 0.067 12.8 0.2 1.2 8.7 0.0 2.6 3 0 0 3 3 2 0 Archaeal ATPase NACHT PF05729.7 AEO64822.1 - 0.071 12.7 0.4 0.53 9.9 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.1 AEO64822.1 - 0.096 11.7 0.0 0.97 8.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 AEO64822.1 - 0.13 11.7 1.4 12 5.1 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.14 AEO64822.1 - 0.13 11.7 3.6 0.24 10.8 0.1 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.4 AEO64822.1 - 0.14 10.7 1.1 4.8 5.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 AEO64822.1 - 0.17 11.4 1.7 10 5.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 AEO64822.1 - 0.19 11.3 0.7 0.46 10.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Dynamin_N PF00350.18 AEO64822.1 - 0.37 10.5 3.4 1.5 8.6 0.3 2.4 2 0 0 2 2 2 0 Dynamin family Zn_clus PF00172.13 AEO64823.1 - 3.9e-09 36.2 8.2 3.9e-09 36.2 5.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO64823.1 - 2.5e-06 26.5 0.5 3.8e-06 25.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 AEO64825.1 - 1e-19 70.4 39.9 1e-19 70.4 27.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 AEO64825.1 - 0.0075 16.0 0.0 0.028 14.2 0.0 2.0 1 0 0 1 1 1 1 MFS_1 like family Sugar_tr PF00083.19 AEO64826.1 - 2.1e-79 267.2 24.6 2.4e-79 267.0 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO64826.1 - 1.1e-15 57.2 39.0 5e-11 41.9 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_11 PF13414.1 AEO64827.1 - 2e-13 49.7 10.2 1.6e-07 30.8 0.0 5.9 5 1 1 6 6 6 3 TPR repeat TPR_2 PF07719.12 AEO64827.1 - 3.5e-09 35.8 12.6 0.0017 18.0 0.0 8.2 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 AEO64827.1 - 5.5e-08 33.0 7.1 0.0099 16.1 0.1 6.1 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 AEO64827.1 - 3.8e-07 29.4 7.1 0.0012 18.3 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 AEO64827.1 - 2.7e-06 27.1 16.3 0.028 14.3 0.6 5.9 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 AEO64827.1 - 3.8e-06 26.2 0.1 1.3 9.0 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 AEO64827.1 - 5.5e-06 26.4 4.7 5.7 7.6 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 AEO64827.1 - 7.1e-06 26.2 25.5 1.2 10.0 0.1 9.0 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO64827.1 - 0.00016 21.2 0.2 0.53 10.2 0.0 5.3 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 AEO64827.1 - 0.0002 21.9 41.0 0.0073 16.9 0.1 7.9 9 2 1 10 10 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 AEO64827.1 - 0.009 16.1 3.1 27 5.2 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TOM20_plant PF06552.7 AEO64827.1 - 0.096 12.2 0.1 22 4.6 0.0 2.9 3 0 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_4 PF07721.9 AEO64827.1 - 0.31 11.5 0.1 0.31 11.5 0.1 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat MFS_1 PF07690.11 AEO64828.1 - 5.4e-35 120.7 8.4 1.1e-34 119.7 5.8 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO64828.1 - 1.1e-11 44.0 3.7 1e-10 40.7 3.0 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 AEO64828.1 - 1.3e-05 23.8 5.3 0.0049 15.3 3.4 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 AEO64828.1 - 0.00099 17.4 0.6 0.0014 16.9 0.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.14 AEO64828.1 - 0.019 13.5 0.4 0.019 13.5 0.3 1.5 2 0 0 2 2 2 0 LacY proton/sugar symporter MFS_1_like PF12832.2 AEO64828.1 - 0.082 12.7 0.7 0.27 11.0 0.0 2.3 2 0 0 2 2 2 0 MFS_1 like family Formyl_trans_N PF00551.14 AEO64829.1 - 3.4e-37 127.7 0.1 4.3e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 AEO64829.1 - 1e-08 34.4 0.0 2.6e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 AEO64829.1 - 0.0011 18.6 0.0 0.003 17.2 0.0 1.8 1 0 0 1 1 1 1 ACT domain Acetyltransf_1 PF00583.19 AEO64830.1 - 1.6e-10 40.8 0.3 3.7e-10 39.6 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO64830.1 - 3.9e-08 33.3 0.0 7.4e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO64830.1 - 4.4e-06 26.5 0.0 4.1e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO64830.1 - 4.8e-06 26.6 0.1 0.00067 19.7 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO64830.1 - 6e-05 22.7 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 AEO64830.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SSF PF00474.12 AEO64831.1 - 1.6e-18 66.5 29.0 2.4e-18 66.0 20.1 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Glyco_hydro_3 PF00933.16 AEO64832.1 - 7.2e-93 310.8 0.0 1e-92 310.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO64832.1 - 2.8e-54 184.0 0.3 5.6e-53 179.7 0.0 2.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO64832.1 - 1.3e-22 79.5 0.2 2.6e-22 78.5 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain ABC_tran PF00005.22 AEO64833.1 - 1.3e-40 138.8 0.0 2.4e-21 76.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AEO64833.1 - 1.3e-35 123.1 20.2 3.2e-23 82.5 7.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.1 AEO64833.1 - 6.6e-10 39.2 3.4 2.9e-05 24.1 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 AEO64833.1 - 2.3e-09 36.8 0.7 4.6e-05 22.7 0.0 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SE PF00437.15 AEO64833.1 - 8e-09 34.7 0.0 0.0008 18.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 AEO64833.1 - 5.1e-08 32.3 0.2 0.0058 16.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 AEO64833.1 - 1e-07 32.1 0.0 0.0066 16.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 AEO64833.1 - 1.2e-07 31.0 0.4 0.041 12.9 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin AAA_21 PF13304.1 AEO64833.1 - 1.4e-06 28.4 1.0 0.092 12.6 0.0 4.4 4 1 1 5 5 5 2 AAA domain AAA_23 PF13476.1 AEO64833.1 - 1.7e-06 28.5 0.0 0.041 14.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 AEO64833.1 - 4.2e-06 26.0 0.1 0.019 14.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 AEO64833.1 - 8.3e-06 26.2 0.0 0.024 15.1 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 AEO64833.1 - 9.6e-06 26.4 0.6 0.19 12.5 0.2 2.6 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 AEO64833.1 - 3.1e-05 23.5 0.0 0.017 14.5 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Arch_ATPase PF01637.13 AEO64833.1 - 3.6e-05 23.5 0.1 0.21 11.2 0.0 3.1 3 0 0 3 3 3 1 Archaeal ATPase AAA_18 PF13238.1 AEO64833.1 - 6.1e-05 23.3 0.1 0.44 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 AEO64833.1 - 6.5e-05 22.8 0.0 0.1 12.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AEO64833.1 - 8.4e-05 22.0 0.2 0.5 9.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 AEO64833.1 - 0.00011 22.0 0.1 0.56 10.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 AEO64833.1 - 0.00012 21.6 0.8 0.26 10.6 0.1 2.6 2 0 0 2 2 2 2 AAA-like domain AAA_19 PF13245.1 AEO64833.1 - 0.00013 21.6 1.1 0.024 14.3 0.0 3.6 3 0 0 3 3 3 1 Part of AAA domain cobW PF02492.14 AEO64833.1 - 0.00018 20.9 0.8 0.057 12.8 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 AEO64833.1 - 0.00052 19.9 0.0 3 7.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 AEO64833.1 - 0.00069 19.4 1.3 0.5 10.1 0.1 2.3 2 0 0 2 2 2 2 Dynamin family NACHT PF05729.7 AEO64833.1 - 0.00073 19.2 0.4 0.13 11.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Adeno_IVa2 PF02456.10 AEO64833.1 - 0.0013 17.4 0.0 0.49 8.9 0.0 2.3 2 0 0 2 2 2 1 Adenovirus IVa2 protein MobB PF03205.9 AEO64833.1 - 0.0019 17.9 0.1 2.2 8.0 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 AEO64833.1 - 0.0026 17.2 0.2 0.99 8.8 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 AEO64833.1 - 0.0046 16.6 0.2 1.1 8.9 0.0 2.3 2 0 0 2 2 2 1 NTPase PIF1 PF05970.9 AEO64833.1 - 0.0058 15.6 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 1 PIF1-like helicase AAA PF00004.24 AEO64833.1 - 0.0066 16.6 0.1 1.1 9.4 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 AEO64833.1 - 0.0072 15.9 0.4 0.23 11.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 TrwB_AAD_bind PF10412.4 AEO64833.1 - 0.011 14.4 0.4 2.3 6.7 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.16 AEO64833.1 - 0.014 14.6 0.1 1.1 8.4 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 AEO64833.1 - 0.014 14.3 0.3 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 AEO64833.1 - 0.015 14.8 0.1 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AEO64833.1 - 0.029 14.5 0.0 12 6.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.12 AEO64833.1 - 0.095 12.2 0.1 5.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SbcCD_C PF13558.1 AEO64833.1 - 0.11 12.4 5.9 0.59 10.0 0.4 3.7 4 1 0 4 4 2 0 Putative exonuclease SbcCD, C subunit Guanylate_kin PF00625.16 AEO64833.1 - 0.12 11.7 0.3 3.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase AAA_28 PF13521.1 AEO64833.1 - 0.13 12.2 0.2 12 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 AEO64833.1 - 0.13 11.7 0.0 4.9 6.6 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase Pox_A32 PF04665.7 AEO64833.1 - 0.15 11.3 0.4 2.6 7.2 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein DUF2075 PF09848.4 AEO64833.1 - 0.23 10.3 0.1 12 4.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA12 PF10443.4 AEO64833.1 - 0.38 9.1 0.2 2.6 6.4 0.0 2.0 2 0 0 2 2 2 0 RNA12 protein NB-ARC PF00931.17 AEO64833.1 - 0.42 9.4 1.9 12 4.7 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain DUF87 PF01935.12 AEO64833.1 - 0.5 10.1 1.1 5.7 6.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 DAP3 PF10236.4 AEO64833.1 - 4.7 6.0 5.6 6.3 5.6 0.1 2.5 3 0 0 3 3 2 0 Mitochondrial ribosomal death-associated protein 3 Cofilin_ADF PF00241.15 AEO64834.1 - 3.2e-16 59.3 0.0 3.6e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein adh_short PF00106.20 AEO64835.1 - 1.8e-15 57.2 0.1 3e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO64835.1 - 6.8e-06 25.8 0.3 1.1e-05 25.1 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO64835.1 - 4.3e-05 23.5 0.1 9.2e-05 22.5 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO64835.1 - 6e-05 22.6 0.0 7.7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Chitin_bind_1 PF00187.14 AEO64837.1 - 2.2e-17 62.7 75.9 3.6e-08 33.2 12.9 4.7 3 2 1 4 4 4 3 Chitin recognition protein Mucin PF01456.12 AEO64837.1 - 0.29 10.9 56.1 0.11 12.2 14.1 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Conotoxin PF02950.12 AEO64837.1 - 3.2 8.6 19.0 2.2 9.1 0.9 3.7 3 0 0 3 3 3 0 Conotoxin LRR_4 PF12799.2 AEO64838.1 - 0.056 13.0 0.4 23 4.7 0.2 3.8 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) Iron_permease PF04120.7 AEO64842.1 - 2.8e-06 26.9 6.1 4.6e-05 23.0 0.1 2.3 2 1 0 2 2 2 2 Low affinity iron permease PBP PF01161.15 AEO64843.1 - 1.4e-18 67.1 0.0 1.7e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ABC_tran PF00005.22 AEO64844.1 - 8.8e-50 168.5 0.0 5.5e-30 104.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AEO64844.1 - 2.5e-38 132.0 26.2 1.1e-29 103.7 8.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 AEO64844.1 - 9.7e-13 47.8 0.7 7.5e-05 22.0 0.1 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AEO64844.1 - 1.4e-10 41.6 0.0 0.00043 20.3 0.0 4.0 3 1 0 4 4 4 2 AAA domain AAA_22 PF13401.1 AEO64844.1 - 6.5e-07 29.5 1.2 0.044 13.9 0.4 3.3 2 1 0 2 2 2 2 AAA domain T2SE PF00437.15 AEO64844.1 - 3e-06 26.3 0.0 0.025 13.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 AEO64844.1 - 6.2e-06 26.3 0.9 0.041 13.8 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 AEO64844.1 - 1.3e-05 25.6 0.4 0.068 13.6 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 AEO64844.1 - 1.4e-05 24.4 0.4 0.042 13.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.1 AEO64844.1 - 4.5e-05 23.3 0.4 0.05 13.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 AEO64844.1 - 0.00013 21.1 0.3 0.15 11.2 0.0 2.5 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 AEO64844.1 - 0.00051 20.4 0.1 0.29 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AEO64844.1 - 0.0007 19.0 0.1 0.47 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 AEO64844.1 - 0.00081 19.5 0.3 0.29 11.3 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 AEO64844.1 - 0.0011 18.9 0.0 1.7 8.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 AEO64844.1 - 0.0016 18.1 1.1 1.7 8.3 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 AEO64844.1 - 0.0016 17.9 0.0 0.1 12.0 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 AEO64844.1 - 0.0025 17.3 1.3 1.3 8.3 0.1 2.8 3 0 0 3 3 3 1 AAA-like domain Arch_ATPase PF01637.13 AEO64844.1 - 0.0025 17.5 0.0 0.34 10.5 0.0 2.7 3 0 0 3 3 2 1 Archaeal ATPase PduV-EutP PF10662.4 AEO64844.1 - 0.0026 17.2 0.8 0.4 10.1 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 AEO64844.1 - 0.0028 18.4 0.5 5 7.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 AEO64844.1 - 0.0076 16.0 1.1 0.99 9.2 0.1 2.7 3 0 0 3 3 2 1 Dynamin family cobW PF02492.14 AEO64844.1 - 0.012 15.0 2.1 1.6 8.1 0.1 2.8 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 AEO64844.1 - 0.013 15.1 2.2 1.4 8.5 0.1 3.0 3 0 0 3 3 2 0 NACHT domain Viral_helicase1 PF01443.13 AEO64844.1 - 0.017 14.6 0.1 1.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Septin PF00735.13 AEO64844.1 - 0.027 13.5 0.1 2.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Septin Zeta_toxin PF06414.7 AEO64844.1 - 0.028 13.5 1.2 5.8 5.9 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin SbcCD_C PF13558.1 AEO64844.1 - 0.031 14.1 0.2 0.48 10.3 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 AEO64844.1 - 0.033 14.3 0.0 7.4 6.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 AEO64844.1 - 0.04 12.7 0.4 6.3 5.5 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain AAA_14 PF13173.1 AEO64844.1 - 0.045 13.6 0.4 2.9 7.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 AEO64844.1 - 0.05 13.9 0.3 16 5.8 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 AEO64844.1 - 0.055 13.0 0.1 0.9 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 AEO64844.1 - 0.1 12.3 0.9 13 5.4 0.1 2.6 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.12 AEO64844.1 - 0.22 11.0 0.7 9.8 5.6 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 AEO64844.1 - 0.22 11.2 1.6 15 5.3 0.1 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DEAD PF00270.24 AEO64844.1 - 0.28 10.6 3.2 1.5 8.3 0.7 2.6 2 1 0 2 2 1 0 DEAD/DEAH box helicase AMP-binding PF00501.23 AEO64845.1 - 0 1420.5 7.6 7.1e-89 298.0 0.5 5.3 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 AEO64845.1 - 0 1222.2 0.0 1e-50 172.3 0.0 11.8 12 2 0 12 12 12 10 Condensation domain PP-binding PF00550.20 AEO64845.1 - 6.1e-75 247.4 1.2 4.5e-13 49.2 0.0 7.9 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 AEO64845.1 - 1.2e-22 80.5 4.6 0.00065 20.5 0.0 6.4 5 0 0 5 5 5 5 AMP-binding enzyme C-terminal domain AATase PF07247.7 AEO64845.1 - 3.5e-06 25.8 0.0 0.2 10.1 0.0 3.7 3 0 0 3 3 3 2 Alcohol acetyltransferase Transferase PF02458.10 AEO64845.1 - 6.1e-06 24.9 0.0 1.3 7.3 0.0 3.6 3 0 0 3 3 3 3 Transferase family DDE_Tnp_1_2 PF13586.1 AEO64845.1 - 0.012 15.7 0.6 0.44 10.7 0.0 3.4 3 0 0 3 3 3 0 Transposase DDE domain RHH_3 PF12651.2 AEO64845.1 - 0.057 13.1 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix domain RAB3GAP2_C PF14656.1 AEO64845.1 - 3 5.8 0.0 43 2.0 0.0 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF1481 PF07356.7 AEO64845.1 - 8.7 5.7 2.2 29 4.0 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1481) Phage_cap_E PF03864.10 AEO64845.1 - 9.3 5.0 0.1 19 4.0 0.0 1.4 1 0 0 1 1 1 0 Phage major capsid protein E ABC2_membrane PF01061.19 AEO64846.1 - 1.4e-91 305.3 47.1 7e-47 159.3 8.4 2.5 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 AEO64846.1 - 2.6e-38 131.4 0.1 4.2e-20 72.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 AEO64846.1 - 3.7e-31 106.8 0.0 7.7e-26 89.7 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 AEO64846.1 - 2.7e-07 30.5 0.2 7.1e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 AEO64846.1 - 2.4e-06 27.4 0.1 0.095 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 AEO64846.1 - 4.2e-06 26.0 29.0 0.0041 16.1 7.6 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 AEO64846.1 - 8e-06 25.3 0.2 0.055 12.8 0.0 3.7 5 0 0 5 5 5 2 AAA domain AAA_21 PF13304.1 AEO64846.1 - 6.6e-05 23.0 0.2 0.06 13.3 0.3 3.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AEO64846.1 - 0.00013 22.1 0.2 0.66 10.1 0.1 3.7 3 1 0 3 3 3 1 AAA domain cobW PF02492.14 AEO64846.1 - 0.00013 21.4 0.0 0.023 14.1 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 AEO64846.1 - 0.00015 21.3 0.0 0.49 9.8 0.0 2.7 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 AEO64846.1 - 0.00015 20.9 0.0 0.0013 17.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 AEO64846.1 - 0.00019 21.7 0.0 0.03 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AEO64846.1 - 0.00033 20.1 0.4 0.16 11.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 AEO64846.1 - 0.0012 18.8 0.1 0.12 12.3 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 AEO64846.1 - 0.0014 18.6 5.9 0.078 12.9 0.6 3.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.1 AEO64846.1 - 0.0017 18.3 0.1 0.0053 16.7 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO64846.1 - 0.0031 18.3 0.0 0.12 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 AEO64846.1 - 0.0072 16.0 0.2 1.1 8.9 0.2 2.5 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 AEO64846.1 - 0.014 15.0 0.4 0.21 11.1 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 AEO64846.1 - 0.017 14.3 0.1 0.29 10.3 0.0 2.7 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 AEO64846.1 - 0.024 14.0 0.8 6.1 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.1 AEO64846.1 - 0.038 13.5 0.2 0.27 10.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 AEO64846.1 - 0.054 14.0 0.1 3.7 8.0 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein PduV-EutP PF10662.4 AEO64846.1 - 0.094 12.1 0.1 0.32 10.4 0.2 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 AEO64846.1 - 0.14 11.1 0.1 0.37 9.7 0.1 1.6 2 0 0 2 2 2 0 Septin NB-ARC PF00931.17 AEO64846.1 - 0.15 10.9 0.4 4 6.2 0.2 2.4 3 0 0 3 3 2 0 NB-ARC domain T2SE PF00437.15 AEO64846.1 - 0.2 10.5 0.0 6.8 5.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.17 AEO64846.1 - 0.23 11.6 0.0 20 5.4 0.1 2.6 2 0 0 2 2 2 0 RNA helicase bZIP_1 PF00170.16 AEO64847.1 - 2.7e-10 40.0 12.7 3.3e-10 39.7 8.8 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AEO64847.1 - 1.3e-08 34.5 17.0 2.6e-08 33.5 10.4 1.9 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.12 AEO64847.1 - 3.1e-05 24.1 9.3 3.6e-05 23.9 6.4 1.0 1 0 0 1 1 1 1 bZIP Maf transcription factor Takusan PF04822.8 AEO64847.1 - 0.00018 21.2 6.4 0.00024 20.7 4.4 1.5 1 1 0 1 1 1 1 Takusan TMF_DNA_bd PF12329.3 AEO64847.1 - 0.024 14.4 6.5 0.028 14.1 4.5 1.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HAUS2 PF15003.1 AEO64847.1 - 0.032 13.3 0.9 0.032 13.3 0.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 Kinetocho_Slk19 PF12709.2 AEO64847.1 - 0.04 13.9 3.8 0.047 13.7 2.7 1.2 1 0 0 1 1 1 0 Central kinetochore-associated Peptidase_A21 PF03566.8 AEO64847.1 - 0.058 11.5 2.4 0.063 11.3 1.7 1.0 1 0 0 1 1 1 0 Peptidase family A21 Seryl_tRNA_N PF02403.17 AEO64847.1 - 0.096 12.7 6.4 0.12 12.3 4.4 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TPD52 PF04201.10 AEO64847.1 - 0.097 12.3 3.7 0.11 12.1 2.6 1.2 1 1 0 1 1 1 0 Tumour protein D52 family DUF4140 PF13600.1 AEO64847.1 - 0.1 13.0 6.1 0.12 12.8 4.2 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF2312 PF10073.4 AEO64847.1 - 0.1 11.9 4.5 0.13 11.6 3.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) MCC-bdg_PDZ PF10506.4 AEO64847.1 - 0.11 12.3 7.7 0.35 10.7 0.9 2.0 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF3450 PF11932.3 AEO64847.1 - 0.12 11.6 5.0 0.14 11.4 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Med9 PF07544.8 AEO64847.1 - 0.13 12.0 2.8 0.5 10.1 1.8 2.0 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 WD40_alt PF14077.1 AEO64847.1 - 0.22 11.1 6.1 0.83 9.3 0.3 2.1 1 1 1 2 2 2 0 Alternative WD40 repeat motif Vac_Fusion PF02346.11 AEO64847.1 - 0.25 10.7 3.3 0.34 10.3 2.3 1.3 1 0 0 1 1 1 0 Chordopoxvirus fusion protein APG6 PF04111.7 AEO64847.1 - 0.27 10.2 5.5 0.28 10.1 3.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1192 PF06698.6 AEO64847.1 - 0.27 11.0 9.0 2.4 8.0 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DUF972 PF06156.8 AEO64847.1 - 0.3 11.4 1.9 0.32 11.3 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3529 PF12046.3 AEO64847.1 - 0.32 10.0 2.7 0.35 9.8 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) DUF4349 PF14257.1 AEO64847.1 - 0.43 9.7 3.5 0.41 9.8 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) IncA PF04156.9 AEO64847.1 - 0.44 10.1 5.6 0.45 10.0 3.9 1.0 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 AEO64847.1 - 0.61 9.6 7.6 1.3 8.5 5.2 1.7 1 1 0 1 1 1 0 Septum formation initiator GrpE PF01025.14 AEO64847.1 - 0.83 9.1 5.5 0.93 9.0 3.8 1.1 1 0 0 1 1 1 0 GrpE CENP-H PF05837.7 AEO64847.1 - 1.3 9.2 6.4 1.5 8.9 4.4 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Med21 PF11221.3 AEO64847.1 - 1.6 8.7 5.7 1.8 8.5 3.9 1.2 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Atg14 PF10186.4 AEO64847.1 - 1.6 7.5 10.3 1.7 7.5 7.1 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF724 PF05266.9 AEO64847.1 - 2.4 7.7 7.6 2.5 7.6 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DASH_Spc19 PF08287.6 AEO64848.1 - 2.8e-39 134.2 0.0 4.3e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Spc19 SH3_1 PF00018.23 AEO64849.1 - 2e-09 36.6 0.1 3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AEO64849.1 - 5e-07 29.1 0.0 8.5e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 AEO64849.1 - 5e-06 25.9 0.0 9.4e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF4404 PF14357.1 AEO64851.1 - 0.0071 16.7 1.5 0.74 10.2 0.4 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4404) Med17 PF10156.4 AEO64851.1 - 0.0093 14.2 0.1 0.012 13.8 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DUF4140 PF13600.1 AEO64851.1 - 0.32 11.4 5.7 2 8.8 0.7 2.5 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) zf-C2H2_4 PF13894.1 AEO64852.1 - 5.5e-06 26.3 8.5 0.0027 17.9 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO64852.1 - 0.00011 22.3 6.0 0.29 11.5 0.0 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 AEO64852.1 - 0.00076 19.6 12.7 0.12 12.7 0.0 3.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-FCS PF06467.9 AEO64852.1 - 0.0061 16.1 0.8 0.33 10.6 0.1 2.3 2 0 0 2 2 2 1 MYM-type Zinc finger with FCS sequence motif zf-ribbon_3 PF13248.1 AEO64852.1 - 0.03 13.5 0.2 0.066 12.4 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-Di19 PF05605.7 AEO64852.1 - 0.11 12.6 6.2 1 9.5 1.0 3.0 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 AEO64852.1 - 0.12 12.5 3.4 0.35 11.0 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF3505 PF12013.3 AEO64852.1 - 0.84 9.9 3.5 5.6 7.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3505) Aa_trans PF01490.13 AEO64853.1 - 9e-80 268.1 11.6 1.2e-79 267.6 8.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 AEO64853.1 - 0.0017 17.1 2.7 0.0035 16.0 1.9 1.5 1 0 0 1 1 1 1 Spore germination protein Ribosomal_S16 PF00886.14 AEO64854.1 - 4.6e-26 90.2 0.2 7.8e-26 89.5 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein S16 YjeF_N PF03853.10 AEO64855.1 - 1e-35 122.8 0.0 1.2e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Glyco_hydro_16 PF00722.16 AEO64856.1 - 4.4e-39 133.6 1.5 7.4e-39 132.9 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF605 PF04652.11 AEO64856.1 - 0.017 14.5 13.2 0.022 14.1 9.2 1.1 1 0 0 1 1 1 0 Vta1 like RNase_T PF00929.19 AEO64857.1 - 9.2e-16 58.5 0.0 1.2e-15 58.2 0.0 1.1 1 0 0 1 1 1 1 Exonuclease F-box-like PF12937.2 AEO64860.1 - 0.00012 21.7 0.0 0.00027 20.5 0.0 1.7 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 AEO64860.1 - 0.0015 18.0 0.2 1.2 8.8 0.2 2.7 2 0 0 2 2 2 2 F-box domain Clr5 PF14420.1 AEO64862.1 - 7.5e-20 70.5 3.6 1.2e-19 69.9 2.5 1.3 1 0 0 1 1 1 1 Clr5 domain FSH1 PF03959.8 AEO64864.1 - 9.6e-58 195.1 0.0 1.2e-57 194.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 AEO64864.1 - 6e-07 29.3 0.2 1e-06 28.5 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO64864.1 - 1.1e-05 25.4 2.9 0.052 13.4 0.7 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 AEO64864.1 - 0.0051 16.2 0.3 3.2 7.1 0.1 3.0 4 0 0 4 4 4 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 AEO64864.1 - 0.024 14.1 0.7 0.72 9.3 0.3 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.13 AEO64864.1 - 0.03 13.6 0.1 3.4 6.9 0.2 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2048 PF09752.4 AEO64864.1 - 0.17 10.7 0.7 0.25 10.1 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) ATP-synt_J PF04911.7 AEO64865.1 - 1.2e-27 95.0 1.5 1.4e-27 94.8 1.1 1.1 1 0 0 1 1 1 1 ATP synthase j chain NIPSNAP PF07978.8 AEO64866.1 - 1.5e-36 124.4 0.2 1.1e-28 99.1 0.1 2.4 2 0 0 2 2 2 2 NIPSNAP DUF566 PF04484.7 AEO64866.1 - 1.2 8.6 8.7 1.7 8.1 6.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) SR-25 PF10500.4 AEO64866.1 - 1.2 8.5 7.2 1.9 7.9 5.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rogdi_lz PF10259.4 AEO64867.1 - 1.9e-85 286.3 0.0 2.2e-85 286.1 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rpp20 PF12328.3 AEO64868.1 - 4e-21 75.1 0.6 5.8e-21 74.6 0.4 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 AEO64868.1 - 1.9e-12 46.6 0.1 2.6e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Alba Chorion_3 PF05387.6 AEO64868.1 - 0.0073 15.7 0.7 0.0083 15.5 0.5 1.1 1 0 0 1 1 1 1 Chorion family 3 K_channel_TID PF07941.6 AEO64868.1 - 0.65 10.2 6.9 2.8 8.2 5.1 1.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Phage_lysis PF03245.8 AEO64868.1 - 0.68 9.9 3.5 1.1 9.2 2.4 1.4 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Pectate_lyase_3 PF12708.2 AEO64870.1 - 3.1e-63 213.9 5.5 2.5e-54 184.7 0.5 2.7 3 0 0 3 3 3 2 Pectate lyase superfamily protein Beta-lactamase PF00144.19 AEO64873.1 - 8.5e-38 130.1 3.2 1.2e-37 129.6 2.2 1.1 1 0 0 1 1 1 1 Beta-lactamase Adeno_VII PF03228.9 AEO64874.1 - 0.18 12.4 4.2 0.21 12.1 1.0 2.0 2 0 0 2 2 2 0 Adenoviral core protein VII V-SNARE PF05008.10 AEO64874.1 - 0.76 9.9 4.8 1.7 8.8 3.2 1.6 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Neisseria_TspB PF05616.8 AEO64874.1 - 1.3 7.3 7.3 1.8 6.8 5.1 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Nucleoporin_FG PF13634.1 AEO64874.1 - 5.9 7.1 15.9 16 5.8 11.0 1.7 1 1 0 1 1 1 0 Nucleoporin FG repeat region RRM_1 PF00076.17 AEO64875.1 - 1e-16 60.3 0.0 1.1e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO64875.1 - 1.4e-13 50.6 0.0 1.5e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO64875.1 - 4.7e-09 35.9 0.0 5.8e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO64875.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 AEO64875.1 - 0.026 14.3 0.0 0.043 13.6 0.0 1.4 1 1 0 1 1 1 0 RNA binding motif ABC_tran PF00005.22 AEO64877.1 - 8.4e-50 168.6 0.0 4.2e-27 95.1 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AEO64877.1 - 3.9e-16 59.8 2.7 4e-06 27.0 0.1 3.6 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 AEO64877.1 - 4.1e-13 49.0 0.2 0.00075 18.7 0.0 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AEO64877.1 - 1.9e-08 34.8 0.1 0.00072 19.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 AEO64877.1 - 8.3e-08 31.6 0.5 0.0081 15.6 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 AEO64877.1 - 5e-07 30.5 0.1 0.012 16.3 0.0 3.2 3 0 0 3 3 2 2 AAA domain Chromo PF00385.19 AEO64877.1 - 7.3e-07 28.7 0.0 1.6e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.18 AEO64877.1 - 1.9e-06 27.8 0.0 0.0094 15.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 AEO64877.1 - 2.6e-06 26.7 0.0 0.36 9.8 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 AEO64877.1 - 5.4e-06 25.6 0.0 0.017 14.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 AEO64877.1 - 9.4e-06 25.4 2.2 0.083 12.8 0.0 3.5 3 1 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 AEO64877.1 - 1.1e-05 25.6 0.1 0.25 11.4 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 AEO64877.1 - 6.3e-05 22.5 2.5 0.3 10.4 0.1 3.5 3 0 0 3 3 3 2 AAA-like domain Miro PF08477.8 AEO64877.1 - 6.6e-05 23.3 0.0 0.078 13.4 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 AEO64877.1 - 0.00025 20.5 0.0 0.36 10.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 AEO64877.1 - 0.00055 19.9 0.0 0.031 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 AEO64877.1 - 0.00059 19.9 0.1 1.8 8.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 AEO64877.1 - 0.00075 19.3 0.0 0.93 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 AEO64877.1 - 0.00076 19.1 0.2 0.56 9.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.12 AEO64877.1 - 0.00077 19.3 0.1 0.24 11.2 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 AEO64877.1 - 0.0013 18.4 0.1 0.35 10.5 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 AEO64877.1 - 0.0014 17.4 0.3 0.55 8.9 0.0 2.4 2 0 0 2 2 2 2 ArgK protein Dynamin_N PF00350.18 AEO64877.1 - 0.0025 17.6 0.1 0.25 11.1 0.0 3.3 3 1 0 3 3 2 1 Dynamin family AAA_18 PF13238.1 AEO64877.1 - 0.0044 17.3 0.1 0.31 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain HEAT_2 PF13646.1 AEO64877.1 - 0.0071 16.6 0.2 0.24 11.7 0.0 3.2 3 0 0 3 3 3 1 HEAT repeats AAA_30 PF13604.1 AEO64877.1 - 0.01 15.4 0.1 8.4 5.9 0.0 3.2 4 0 0 4 4 2 0 AAA domain AAA PF00004.24 AEO64877.1 - 0.01 16.0 0.0 5 7.3 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.1 AEO64877.1 - 0.017 13.6 0.1 4.9 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 AEO64877.1 - 0.018 14.9 0.0 4 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 AEO64877.1 - 0.018 14.4 0.1 2.5 7.5 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 AEO64877.1 - 0.023 14.4 0.1 8.3 6.0 0.0 3.1 3 0 0 3 3 3 0 Archaeal ATPase PduV-EutP PF10662.4 AEO64877.1 - 0.024 14.1 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 AEO64877.1 - 0.04 12.8 0.1 2.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 AEO64877.1 - 0.048 13.6 0.4 2 8.3 0.1 3.1 3 0 0 3 3 2 0 AAA ATPase domain HEAT PF02985.17 AEO64877.1 - 0.074 13.1 1.0 39 4.7 0.0 4.5 5 0 0 5 5 3 0 HEAT repeat DUF3584 PF12128.3 AEO64877.1 - 0.079 10.2 0.3 2.7 5.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) MutS_V PF00488.16 AEO64877.1 - 0.14 11.5 0.1 5.8 6.2 0.0 2.3 2 0 0 2 2 2 0 MutS domain V NTPase_1 PF03266.10 AEO64877.1 - 0.73 9.5 3.5 17 5.0 0.2 2.9 3 0 0 3 3 2 0 NTPase Glyco_trans_2_3 PF13632.1 AEO64878.1 - 1.5e-47 161.8 5.2 1.5e-47 161.8 3.6 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AEO64878.1 - 1.5e-07 31.4 0.0 3.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 AEO64878.1 - 1.2e-06 28.2 0.0 6.1e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 AEO64878.1 - 0.0053 16.0 0.0 0.014 14.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 AEO64879.1 - 1.1e-18 67.1 0.1 1.5e-17 63.4 0.0 2.3 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Arabinose_trans PF04602.7 AEO64879.1 - 0.055 11.6 0.0 0.081 11.0 0.0 1.1 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein TaqI_C PF12950.2 AEO64879.1 - 0.1 12.3 0.1 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 TaqI-like C-terminal specificity domain Peptidase_C2 PF00648.16 AEO64880.1 - 5.7e-05 22.2 0.0 0.00028 20.0 0.0 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease LIME1 PF15332.1 AEO64880.1 - 0.06 12.5 0.0 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Lck-interacting transmembrane adapter 1 CAP PF00188.21 AEO64881.1 - 1.4e-17 64.3 2.6 2.1e-17 63.7 1.8 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family FAP PF07174.6 AEO64881.1 - 0.024 13.9 22.7 0.038 13.2 15.8 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) TFIIA PF03153.8 AEO64881.1 - 1.9 8.3 7.0 2.4 7.9 4.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 AEO64881.1 - 3.4 6.9 25.5 4.6 6.5 17.6 1.1 1 0 0 1 1 1 0 Vta1 like CHCH PF06747.8 AEO64882.1 - 3.3e-09 36.4 15.4 2.6e-08 33.5 3.7 2.6 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 AEO64882.1 - 2.8e-05 23.7 11.0 0.018 14.7 2.6 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.6 AEO64882.1 - 0.1 12.7 0.5 0.1 12.7 0.4 2.2 1 1 1 2 2 2 0 GCK domain Pet191_N PF10203.4 AEO64882.1 - 0.15 12.1 8.2 0.9 9.6 5.0 2.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.11 AEO64882.1 - 4.7 7.2 7.0 8.1 6.4 3.5 2.3 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Nup54 PF13874.1 AEO64883.1 - 8.8e-44 148.6 0.2 8.8e-44 148.6 0.1 3.1 3 1 0 3 3 3 1 Nucleoporin complex subunit 54 Pex14_N PF04695.8 AEO64883.1 - 0.29 11.2 7.4 0.64 10.0 5.1 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FlaC_arch PF05377.6 AEO64883.1 - 0.46 10.4 2.7 3.5 7.5 0.3 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) RAB3GAP2_N PF14655.1 AEO64883.1 - 1.3 7.9 6.2 2.3 7.1 4.3 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4407 PF14362.1 AEO64883.1 - 1.6 7.6 9.0 5.7 5.7 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Suf PF05843.9 AEO64883.1 - 5.4 6.6 9.5 1.4 8.5 3.9 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) GDC-P PF02347.11 AEO64884.1 - 1e-170 568.1 0.0 4.3e-158 526.5 0.0 3.4 4 0 0 4 4 4 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 AEO64884.1 - 3e-07 29.8 0.1 5.3e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 AEO64884.1 - 2e-06 26.7 0.0 1.4e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V B12-binding PF02310.14 AEO64884.1 - 0.13 12.1 0.2 2.5 8.0 0.0 3.0 4 0 0 4 4 4 0 B12 binding domain WD40 PF00400.27 AEO64885.1 - 4.2e-33 112.0 6.1 3.7e-06 26.6 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 AEO64885.1 - 0.004 16.6 0.0 5 6.7 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain AMP-binding PF00501.23 AEO64886.1 - 2.9e-69 233.4 0.2 5.1e-68 229.3 0.1 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO64886.1 - 3.6e-12 47.0 0.0 1e-11 45.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Toxin_52 PF15605.1 AEO64887.1 - 0.023 14.5 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Putative toxin 52 Gln-synt_C PF00120.19 AEO64888.1 - 2.4e-63 213.6 0.0 3e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Flavodoxin_3 PF12641.2 AEO64889.1 - 0.27 10.6 3.5 5.9 6.2 0.1 2.2 1 1 1 2 2 2 0 Flavodoxin domain Citrate_synt PF00285.16 AEO64890.1 - 2e-101 339.3 0.0 2.4e-101 339.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase DUF4360 PF14273.1 AEO64891.1 - 1.3e-75 253.0 5.1 1.5e-75 252.8 3.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) hGDE_N PF14699.1 AEO64891.1 - 0.11 12.3 0.1 0.22 11.4 0.1 1.6 1 1 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme Thioredox_DsbH PF03190.10 AEO64895.1 - 4.3e-59 198.8 0.0 7e-59 198.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 AEO64895.1 - 7.4e-05 22.6 0.0 0.0026 17.7 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin-like DUF1680 PF07944.7 AEO64895.1 - 0.32 9.1 0.1 2.4 6.2 0.0 2.0 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) DLIC PF05783.6 AEO64896.1 - 9.4e-33 113.5 0.1 1.3e-29 103.1 0.0 2.3 3 0 0 3 3 3 2 Dynein light intermediate chain (DLIC) Phage_tail_2 PF06199.6 AEO64896.1 - 0.004 17.2 0.2 0.0077 16.2 0.1 1.4 1 0 0 1 1 1 1 Phage major tail protein 2 Bax1-I PF01027.15 AEO64897.1 - 2.6e-48 164.3 26.4 3.1e-48 164.1 18.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spore_YhaL PF14147.1 AEO64897.1 - 0.065 12.6 0.1 0.27 10.7 0.0 2.1 1 0 0 1 1 1 0 Sporulation protein YhaL Orbi_NS3 PF01616.11 AEO64897.1 - 0.37 9.7 1.5 2.2 7.2 0.2 2.2 2 0 0 2 2 2 0 Orbivirus NS3 7TMR-DISM_7TM PF07695.6 AEO64897.1 - 4.4 6.9 28.1 12 5.5 9.9 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Septin PF00735.13 AEO64898.1 - 3e-106 354.5 0.1 6.6e-106 353.4 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 AEO64898.1 - 4.3e-05 23.4 0.0 8.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AEO64898.1 - 0.0015 18.3 4.0 0.66 9.7 0.0 3.0 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 AEO64898.1 - 0.0017 17.5 0.2 0.0045 16.1 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 AEO64898.1 - 0.0086 16.8 3.2 0.046 14.5 0.1 2.8 2 2 0 2 2 2 1 AAA domain AAA_24 PF13479.1 AEO64898.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 AEO64898.1 - 0.019 15.4 0.4 0.053 14.0 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 AEO64898.1 - 0.023 14.1 0.2 0.068 12.5 0.1 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain IIGP PF05049.8 AEO64898.1 - 0.062 12.1 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Ribosomal_60s PF00428.14 AEO64898.1 - 0.064 13.6 5.5 0.18 12.2 3.8 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein AIG1 PF04548.11 AEO64898.1 - 0.065 12.3 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_22 PF13401.1 AEO64898.1 - 0.077 13.1 0.8 0.21 11.7 0.1 2.1 2 2 0 2 2 2 0 AAA domain V_ATPase_I PF01496.14 AEO64898.1 - 1.8 6.3 3.6 2.8 5.6 2.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FtsK_SpoIIIE PF01580.13 AEO64898.1 - 2.1 7.7 6.3 0.25 10.7 0.1 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family WD40 PF00400.27 AEO64899.1 - 3.5e-10 39.3 1.9 0.0024 17.6 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Nbas_N PF15492.1 AEO64899.1 - 0.044 12.8 0.0 0.32 10.0 0.0 2.0 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal BBE PF08031.7 AEO64899.1 - 0.093 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Berberine and berberine like Gmad1 PF10647.4 AEO64899.1 - 0.28 10.5 2.0 8 5.7 0.1 2.8 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain RRM_1 PF00076.17 AEO64900.1 - 2.1e-16 59.3 0.0 2e-15 56.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO64900.1 - 1.7e-09 37.5 0.0 3.4e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO64900.1 - 8.1e-06 25.5 0.0 2.1e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRAM_LAG1_CLN8 PF03798.11 AEO64901.1 - 5.8e-47 159.8 13.5 8.5e-47 159.2 9.4 1.2 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 AEO64901.1 - 1.1e-18 66.4 0.0 2.6e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein Lipase_GDSL_2 PF13472.1 AEO64902.1 - 5.7e-11 42.8 0.8 8.8e-11 42.2 0.6 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO64902.1 - 1.4e-09 38.1 0.1 2.3e-09 37.4 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Fungal_trans PF04082.13 AEO64903.1 - 7e-09 34.9 0.0 1e-07 31.0 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain zf-C2H2_jaz PF12171.3 AEO64904.1 - 0.0013 18.8 2.6 0.0019 18.2 1.8 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 AEO64904.1 - 0.013 15.8 0.3 0.021 15.1 0.2 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.2 AEO64904.1 - 0.032 14.4 0.5 0.05 13.8 0.3 1.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type RVT_1 PF00078.22 AEO64905.1 - 0.0071 15.7 0.5 0.0071 15.7 0.3 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HlyIII PF03006.15 AEO64905.1 - 0.12 11.7 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Haemolysin-III related DUF1691 PF07950.6 AEO64906.1 - 6.6e-38 129.0 7.7 6.9e-25 87.1 1.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Herpes_US9 PF06072.6 AEO64906.1 - 0.0011 18.7 1.0 0.0027 17.5 0.7 1.6 1 0 0 1 1 1 1 Alphaherpesvirus tegument protein US9 DUF2562 PF10814.3 AEO64906.1 - 0.028 14.3 1.9 0.096 12.6 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) GCV_T_C PF08669.6 AEO64906.1 - 0.029 14.3 0.9 8.7 6.4 0.2 2.8 3 0 0 3 3 3 0 Glycine cleavage T-protein C-terminal barrel domain ATP-grasp_4 PF13535.1 AEO64907.1 - 0.0092 15.7 0.0 0.037 13.7 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain Grp1_Fun34_YaaH PF01184.14 AEO64908.1 - 8.3e-18 64.4 15.3 9.9e-18 64.1 10.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3096 PF11295.3 AEO64908.1 - 0.07 12.6 0.4 0.07 12.6 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) DUF485 PF04341.7 AEO64908.1 - 7.2 6.3 18.6 2.7 7.7 0.2 3.3 2 1 2 4 4 4 0 Protein of unknown function, DUF485 adh_short_C2 PF13561.1 AEO64909.1 - 1.4e-19 70.8 0.4 2.7e-19 69.9 0.3 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AEO64909.1 - 5.6e-19 68.6 8.2 3.8e-18 65.9 5.7 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO64909.1 - 1.7e-09 37.5 0.5 1.7e-09 37.5 0.3 2.1 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 AEO64909.1 - 0.00028 20.9 0.1 0.00061 19.8 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 AEO64909.1 - 0.00057 19.9 4.4 0.044 13.7 3.1 2.5 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 AEO64909.1 - 0.0011 17.9 0.2 0.0022 16.9 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 AEO64909.1 - 0.013 14.9 0.4 0.028 13.8 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 AEO64909.1 - 0.02 14.3 0.0 0.093 12.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_7 PF13241.1 AEO64909.1 - 0.088 13.0 0.4 0.28 11.4 0.1 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding SWIRM PF04433.12 AEO64910.1 - 6.7e-17 61.4 0.1 1.5e-14 53.8 0.0 2.3 2 0 0 2 2 2 2 SWIRM domain RTA1 PF04479.8 AEO64912.1 - 5.2e-09 35.9 6.2 2.3e-08 33.8 4.3 1.9 1 1 0 1 1 1 1 RTA1 like protein SepZ PF06066.6 AEO64912.1 - 0.074 13.0 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 SepZ Fungal_trans_2 PF11951.3 AEO64913.1 - 9.9e-11 40.8 0.1 3e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain P19Arf_N PF07392.7 AEO64913.1 - 0.36 11.0 0.1 0.36 11.0 0.1 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus Zn_clus PF00172.13 AEO64914.1 - 9.2e-05 22.2 9.5 0.00012 21.8 6.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SGL PF08450.7 AEO64915.1 - 2e-26 92.8 0.3 7e-26 91.1 0.2 2.0 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 AEO64915.1 - 5.7e-06 26.2 0.0 8.8e-05 22.4 0.0 2.4 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 AEO64915.1 - 0.00024 21.0 0.1 0.0027 17.6 0.0 2.4 2 0 0 2 2 2 1 Arylesterase NHL PF01436.16 AEO64915.1 - 0.00043 20.1 1.8 0.042 13.8 0.0 3.8 4 0 0 4 4 4 1 NHL repeat HET PF06985.6 AEO64916.1 - 2.2e-21 76.4 0.3 3.1e-21 76.0 0.2 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NADH-u_ox-rdase PF10785.4 AEO64917.1 - 4.5e-37 126.1 0.5 7.1e-37 125.5 0.4 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 AEO64917.1 - 3.1e-31 106.9 0.0 4.5e-31 106.4 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Swi3 PF07962.7 AEO64918.1 - 1.5e-28 98.1 0.2 2.6e-28 97.4 0.1 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 ICL PF00463.16 AEO64919.1 - 2.1e-194 646.6 0.1 2.4e-194 646.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 AEO64919.1 - 3.5e-13 49.3 0.1 7.5e-11 41.6 0.0 2.3 2 0 0 2 2 2 2 Phosphoenolpyruvate phosphomutase adh_short PF00106.20 AEO64920.1 - 4.9e-27 94.8 1.8 6.8e-27 94.4 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO64920.1 - 5.9e-18 65.5 0.0 7.1e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO64920.1 - 9.9e-10 38.3 0.8 1.5e-09 37.8 0.6 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 AEO64920.1 - 3.8e-05 23.4 0.2 6.5e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_12 PF08242.7 AEO64920.1 - 0.0017 18.7 0.1 0.0062 16.9 0.1 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO64920.1 - 0.0051 17.3 0.1 0.025 15.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain THF_DHG_CYH_C PF02882.14 AEO64920.1 - 0.0076 15.3 0.2 0.02 13.9 0.0 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UDPG_MGDP_dh_N PF03721.9 AEO64920.1 - 0.03 13.6 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Polysacc_synt_2 PF02719.10 AEO64920.1 - 0.045 12.6 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_11 PF08241.7 AEO64920.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_10 PF13460.1 AEO64920.1 - 0.07 13.1 1.2 0.19 11.7 0.3 2.0 1 1 0 2 2 2 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 AEO64920.1 - 0.28 10.9 2.6 0.97 9.2 0.5 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DSHCT PF08148.7 AEO64921.1 - 2.1e-61 206.2 0.9 4.2e-61 205.3 0.6 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 AEO64921.1 - 9.2e-21 74.0 0.0 2.4e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO64921.1 - 3.5e-06 26.7 1.0 1.3e-05 24.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 AEO64921.1 - 9.6e-05 21.6 0.1 0.0025 17.0 0.0 2.3 2 0 0 2 2 2 1 rRNA-processing arch domain Snf7 PF03357.16 AEO64922.1 - 2.8e-05 23.5 12.9 4.3e-05 22.9 8.9 1.2 1 0 0 1 1 1 1 Snf7 XLF PF09302.6 AEO64922.1 - 0.022 14.5 0.2 0.055 13.2 0.0 1.7 1 1 1 2 2 2 0 XLF (XRCC4-like factor) DUF427 PF04248.7 AEO64923.1 - 1.4e-19 69.5 0.1 2e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) bZIP_2 PF07716.10 AEO64924.1 - 7.6e-07 28.8 16.0 7.6e-07 28.8 11.1 2.4 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 AEO64924.1 - 0.00065 19.6 13.9 0.0014 18.5 9.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 AEO64924.1 - 0.099 12.9 10.0 0.3 11.4 6.9 1.8 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF1680 PF07944.7 AEO64925.1 - 3e-108 362.3 0.0 3.6e-108 362.1 0.0 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Sugar_tr PF00083.19 AEO64926.1 - 3.9e-75 253.1 16.0 4.5e-75 252.9 11.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO64926.1 - 1.2e-29 103.1 46.2 3.1e-24 85.3 18.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRAM_LAG1_CLN8 PF03798.11 AEO64927.1 - 1.9e-33 115.7 14.7 1.9e-33 115.7 10.2 1.6 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 AEO64927.1 - 1.1e-21 76.0 0.0 3.1e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein GMC_oxred_N PF00732.14 AEO64928.1 - 2.9e-77 259.7 0.0 3.9e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO64928.1 - 9.7e-38 129.6 0.0 3.9e-37 127.7 0.0 2.0 2 1 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 AEO64928.1 - 6.1e-05 22.0 1.1 0.023 13.5 0.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 AEO64928.1 - 0.0015 17.4 0.1 0.0024 16.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 AEO64928.1 - 0.0077 15.1 0.1 2 7.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 AEO64928.1 - 0.13 11.3 0.1 0.36 9.8 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Pex16 PF08610.5 AEO64929.1 - 3.7e-102 341.7 0.0 4.3e-102 341.5 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) GST_N_3 PF13417.1 AEO64930.1 - 2e-18 66.3 0.1 4e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO64930.1 - 1.3e-14 53.8 0.0 2.5e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 AEO64930.1 - 9.7e-11 41.6 0.0 1.8e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 AEO64930.1 - 5e-06 26.4 0.0 7.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 AEO64930.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AEO64930.1 - 0.076 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CBM-like PF14683.1 AEO64931.1 - 1.2e-12 47.8 0.0 2.2e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 AEO64931.1 - 3.6e-10 39.8 0.5 8.9e-10 38.5 0.4 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II p450 PF00067.17 AEO64932.1 - 1.2e-36 126.2 0.0 2.5e-36 125.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_11 PF08241.7 AEO64933.1 - 8.8e-24 83.8 0.0 1.4e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO64933.1 - 3.9e-23 81.7 0.0 5e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO64933.1 - 1.8e-17 63.2 0.0 4.3e-17 62.0 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 AEO64933.1 - 8.6e-17 61.4 0.0 1.3e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO64933.1 - 3.5e-15 56.1 0.0 6e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO64933.1 - 2.1e-14 54.0 0.0 3.8e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO64933.1 - 3e-13 49.7 0.0 4.2e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO64933.1 - 7.6e-10 38.8 0.6 1.5e-09 37.9 0.4 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 AEO64933.1 - 6.7e-08 31.3 0.0 9.8e-08 30.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 AEO64933.1 - 1.3e-06 27.8 0.0 2.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 AEO64933.1 - 5.3e-06 26.1 0.0 7.6e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 AEO64933.1 - 7.8e-06 25.3 0.0 1.7e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 AEO64933.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 AEO64933.1 - 0.0022 18.0 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase DREV PF05219.7 AEO64933.1 - 0.0028 16.5 0.0 0.0058 15.5 0.0 1.6 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_PK PF05891.7 AEO64933.1 - 0.005 16.1 0.0 0.007 15.6 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_8 PF05148.10 AEO64933.1 - 0.012 15.2 0.0 0.039 13.5 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase GCD14 PF08704.5 AEO64933.1 - 0.014 14.9 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_19 PF04672.7 AEO64933.1 - 0.028 13.6 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase Methyltransf_20 PF12147.3 AEO64933.1 - 0.049 12.5 0.0 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.13 AEO64933.1 - 0.086 12.4 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 p450 PF00067.17 AEO64934.1 - 1.3e-33 116.2 0.0 1.4e-28 99.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF4091 PF13320.1 AEO64935.1 - 0.066 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) Acetyltransf_7 PF13508.1 AEO64936.1 - 1.7e-08 34.5 0.0 2.5e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO64936.1 - 1.1e-07 31.7 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AEO64936.1 - 0.00041 20.4 0.0 0.00058 19.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO64936.1 - 0.001 18.7 0.1 0.002 17.8 0.1 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 AEO64936.1 - 0.028 14.2 0.1 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Kelch_5 PF13854.1 AEO64937.1 - 1e-09 38.0 0.7 1.2e-06 28.2 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 AEO64937.1 - 2.5e-05 24.3 9.7 0.93 9.7 0.0 5.7 5 0 0 5 5 5 3 Galactose oxidase, central domain HLH PF00010.21 AEO64939.1 - 1.3e-16 59.9 0.0 2.2e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Herpes_TAF50 PF03326.8 AEO64939.1 - 0.003 16.5 10.5 0.0038 16.2 7.2 1.2 1 0 0 1 1 1 1 Herpesvirus transcription activation factor (transactivator) bZIP_2 PF07716.10 AEO64939.1 - 0.18 11.6 1.6 0.78 9.6 0.1 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Abhydrolase_6 PF12697.2 AEO64940.1 - 0.00078 19.3 0.0 0.00088 19.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO64940.1 - 0.04 13.4 0.0 0.043 13.3 0.0 1.0 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2296 PF10058.4 AEO64943.1 - 1.1e-19 69.8 0.1 2e-19 69.0 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF3611 PF12263.3 AEO64943.1 - 0.036 13.4 0.1 0.059 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) DUF2839 PF10999.3 AEO64943.1 - 0.07 13.1 0.1 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) zf-RanBP PF00641.13 AEO64943.1 - 0.21 10.7 2.4 1.3 8.2 0.2 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others GRIP PF01465.15 AEO64944.1 - 8.8e-16 57.1 0.1 1.7e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 GRIP domain IncA PF04156.9 AEO64944.1 - 2.7e-07 30.3 153.7 0.0053 16.3 16.9 7.6 2 2 6 8 8 8 6 IncA protein Reo_sigmaC PF04582.7 AEO64944.1 - 3.1e-07 29.9 42.3 0.024 13.8 4.4 6.8 5 2 2 7 7 7 4 Reovirus sigma C capsid protein GAS PF13851.1 AEO64944.1 - 9.1e-06 25.0 137.6 0.008 15.3 16.8 9.0 3 2 5 9 9 9 8 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 AEO64944.1 - 0.00023 20.8 22.5 0.00023 20.8 15.6 8.9 3 2 5 8 8 7 1 TPR/MLP1/MLP2-like protein DUF3584 PF12128.3 AEO64944.1 - 0.0004 17.8 25.3 0.0004 17.8 17.5 4.7 2 2 3 5 5 5 4 Protein of unknown function (DUF3584) ATG16 PF08614.6 AEO64944.1 - 0.0023 17.7 21.6 0.0023 17.7 15.0 9.5 3 2 4 8 8 8 3 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.6 AEO64944.1 - 0.0033 16.8 6.7 0.0033 16.8 4.6 10.4 3 2 8 11 11 10 2 Phage minor structural protein GP20 DivIC PF04977.10 AEO64944.1 - 0.0069 15.8 1.6 0.0069 15.8 1.1 14.9 8 3 6 15 15 14 6 Septum formation initiator HOOK PF05622.7 AEO64944.1 - 0.012 13.5 123.9 0.088 10.5 12.8 6.1 3 1 3 6 6 6 0 HOOK protein CENP-F_leu_zip PF10473.4 AEO64944.1 - 0.12 12.2 157.2 0.11 12.3 6.6 9.2 3 2 7 10 10 9 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 AEO64944.1 - 0.35 9.2 100.5 0.07 11.5 16.9 5.2 2 2 2 5 5 5 0 AAA domain Myosin_tail_1 PF01576.14 AEO64944.1 - 1.3 6.6 157.7 0.063 11.0 27.5 5.8 3 1 2 5 5 5 0 Myosin tail Baculo_PEP_C PF04513.7 AEO64944.1 - 1.4 8.7 40.5 0.49 10.2 2.3 7.6 5 2 3 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 AEO64944.1 - 5.6 6.3 135.4 0.54 9.6 36.2 8.1 2 2 4 6 6 6 0 Intermediate filament protein Xan_ur_permease PF00860.15 AEO64945.1 - 2.2e-22 79.1 22.6 7.9e-21 73.9 15.6 2.2 1 1 0 1 1 1 1 Permease family Sulfate_transp PF00916.15 AEO64945.1 - 5.3e-05 22.3 3.8 5.3e-05 22.3 2.7 2.3 2 1 1 3 3 3 1 Sulfate transporter family GFA PF04828.9 AEO64946.1 - 3e-16 59.1 16.8 4.2e-09 36.2 1.5 3.9 5 0 0 5 5 4 3 Glutathione-dependent formaldehyde-activating enzyme PPP4R2 PF09184.6 AEO64946.1 - 0.01 15.3 6.1 0.015 14.9 4.2 1.1 1 0 0 1 1 1 0 PPP4R2 NOB1_Zn_bind PF08772.6 AEO64946.1 - 0.026 14.3 2.3 4.1 7.2 0.4 3.1 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Ribosomal_S27 PF01599.14 AEO64946.1 - 0.03 14.1 3.4 0.28 11.0 0.1 2.7 2 0 0 2 2 2 0 Ribosomal protein S27a DDHD PF02862.12 AEO64946.1 - 0.059 13.1 5.3 0.093 12.5 3.7 1.3 1 0 0 1 1 1 0 DDHD domain Suf PF05843.9 AEO64946.1 - 0.13 11.9 11.9 0.2 11.3 8.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) IncA PF04156.9 AEO64946.1 - 0.39 10.3 11.4 0.6 9.6 7.9 1.2 1 0 0 1 1 1 0 IncA protein Ycf1 PF05758.7 AEO64946.1 - 0.72 7.4 6.6 0.9 7.1 4.6 1.0 1 0 0 1 1 1 0 Ycf1 Spc7_N PF15402.1 AEO64946.1 - 0.94 7.4 15.8 1.4 6.8 10.9 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 AvrE PF11725.3 AEO64946.1 - 2.1 5.2 9.9 2.6 4.9 6.9 1.0 1 0 0 1 1 1 0 Pathogenicity factor Zip PF02535.17 AEO64946.1 - 2.8 6.8 6.5 4.2 6.2 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDK5_activator PF03261.10 AEO64946.1 - 3.1 7.0 8.7 4.6 6.4 6.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Neur_chan_memb PF02932.11 AEO64946.1 - 3.4 7.5 6.2 6.1 6.6 4.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1510 PF07423.6 AEO64946.1 - 5.3 6.3 16.7 7.9 5.7 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDRGK PF09756.4 AEO64946.1 - 5.8 6.2 22.2 8.8 5.6 15.4 1.1 1 0 0 1 1 1 0 DDRGK domain BTV_NS2 PF04514.7 AEO64946.1 - 8.8 5.0 10.1 13 4.5 7.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Spore_coat_CotO PF14153.1 AEO64946.1 - 10 5.5 21.8 15 4.9 15.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO dCMP_cyt_deam_1 PF00383.17 AEO64947.1 - 8.7e-22 76.7 0.0 2.8e-21 75.0 0.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 AEO64947.1 - 0.0015 18.4 0.0 0.0082 15.9 0.0 2.2 1 1 1 2 2 2 1 Bd3614-like deaminase APOBEC_N PF08210.6 AEO64947.1 - 0.14 11.7 0.0 0.49 9.9 0.0 1.7 1 1 0 1 1 1 0 APOBEC-like N-terminal domain Zn_clus PF00172.13 AEO64948.1 - 0.03 14.2 8.6 0.062 13.2 5.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PXPV PF12778.2 AEO64948.1 - 2 8.1 11.8 12 5.6 0.5 3.4 2 0 0 2 2 2 0 PXPV repeat (3 copies) DUF2439 PF10382.4 AEO64950.1 - 5.6e-26 90.5 0.1 9.7e-26 89.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Drf_GBD PF06371.8 AEO64950.1 - 0.34 10.2 0.1 0.84 8.9 0.1 1.6 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain Glyco_hydro_43 PF04616.9 AEO64951.1 - 5.6e-34 117.5 6.5 7.5e-34 117.1 4.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 LSR PF05624.9 AEO64952.1 - 5 6.9 7.5 10 5.9 5.2 1.6 1 1 0 1 1 1 0 Lipolysis stimulated receptor (LSR) CBM_1 PF00734.13 AEO64954.1 - 8e-15 54.2 11.0 2.5e-14 52.6 7.6 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.1 AEO64954.1 - 1.4e-14 54.6 4.7 3.2e-14 53.4 3.3 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO64954.1 - 3.5e-09 36.8 0.2 6.3e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 AEO64954.1 - 0.013 15.2 0.0 0.032 13.9 0.0 1.7 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family BAR PF03114.13 AEO64955.1 - 8.1e-14 51.6 0.6 1.4e-13 50.9 0.4 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 AEO64955.1 - 8.5e-14 50.8 0.1 2.1e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AEO64955.1 - 2.3e-11 42.9 0.3 5.6e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 AEO64955.1 - 4.2e-10 38.9 0.2 1.3e-09 37.3 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain Fer2_4 PF13510.1 AEO64956.1 - 0.14 11.9 0.1 2.1 8.2 0.1 2.5 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain MARVEL PF01284.18 AEO64957.1 - 0.00056 19.7 9.8 0.00056 19.7 6.8 2.1 1 1 0 2 2 2 1 Membrane-associating domain Choline_transpo PF04515.7 AEO64957.1 - 0.17 10.6 6.8 0.22 10.2 4.0 1.7 1 1 0 1 1 1 0 Plasma-membrane choline transporter DUF4349 PF14257.1 AEO64957.1 - 7.5 5.6 7.3 27 3.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) zf-RanBP PF00641.13 AEO64959.1 - 0.92 8.6 8.4 0.26 10.4 3.7 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Y_phosphatase3 PF13350.1 AEO64960.1 - 1.7e-43 148.7 0.0 2.4e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 AEO64960.1 - 5.2e-17 61.7 0.2 1.2e-16 60.5 0.1 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 AEO64960.1 - 0.00013 21.3 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 AEO64960.1 - 0.00042 19.7 0.0 0.00068 19.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 AEO64960.1 - 0.007 15.9 0.0 0.018 14.6 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 AEO64960.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Bot1p PF12298.3 AEO64961.1 - 3.2e-51 173.6 5.7 5.1e-51 173.0 4.0 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Response_reg PF00072.19 AEO64962.1 - 5.7e-21 74.6 0.0 3e-14 52.9 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain AAA_10 PF12846.2 AEO64963.1 - 1.2e-08 34.7 0.0 6e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 AEO64963.1 - 0.0022 17.4 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_16 PF13191.1 AEO64963.1 - 0.0076 16.2 0.0 0.29 11.0 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.12 AEO64963.1 - 0.063 13.0 0.0 0.59 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 AEO64963.1 - 0.071 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF2052 PF09747.4 AEO64964.1 - 3.9e-36 124.6 2.1 6.1e-36 124.0 1.5 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Gag_spuma PF03276.9 AEO64965.1 - 0.4 8.9 2.4 0.5 8.6 1.6 1.1 1 0 0 1 1 1 0 Spumavirus gag protein SKG6 PF08693.5 AEO64966.1 - 0.014 14.6 0.3 0.028 13.7 0.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Shisa PF13908.1 AEO64966.1 - 0.055 13.6 17.2 0.033 14.3 0.8 2.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator PepSY_2 PF13670.1 AEO64966.1 - 0.18 11.7 5.4 0.73 9.7 3.7 2.1 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF533 PF04391.7 AEO64966.1 - 0.8 9.0 14.9 2 7.7 6.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Hamartin PF04388.7 AEO64966.1 - 3.8 6.0 7.8 4.9 5.6 5.4 1.1 1 0 0 1 1 1 0 Hamartin protein RskA PF10099.4 AEO64966.1 - 4.5 6.9 21.8 0.29 10.8 5.1 3.2 2 1 0 3 3 3 0 Anti-sigma-K factor rskA Glyco_hydro_43 PF04616.9 AEO64967.1 - 4.5e-28 98.1 3.0 1e-26 93.7 2.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Acetyltransf_1 PF00583.19 AEO64968.1 - 2.3e-11 43.5 0.1 5.1e-11 42.4 0.1 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO64968.1 - 1.6e-09 37.7 0.0 2.8e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.2 AEO64969.1 - 9.2e-12 45.3 0.4 2e-11 44.1 0.1 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO64969.1 - 3.4e-11 43.0 0.0 5.5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 AEO64969.1 - 1.9e-07 30.0 0.0 3.3e-07 29.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 AEO64969.1 - 1.3e-06 27.7 0.0 2.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 AEO64969.1 - 0.00067 18.9 0.0 0.0017 17.6 0.0 1.6 2 0 0 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.15 AEO64969.1 - 0.00069 19.1 0.0 0.0023 17.4 0.0 1.9 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 AEO64969.1 - 0.0083 15.7 0.3 0.075 12.5 0.2 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 AEO64969.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) adh_short PF00106.20 AEO64970.1 - 2.6e-32 112.0 0.9 3.9e-32 111.4 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO64970.1 - 2.5e-23 83.1 0.0 3.5e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO64970.1 - 6.5e-16 58.5 0.9 1.6e-15 57.2 0.6 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO64970.1 - 7.2e-06 25.6 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 AEO64970.1 - 0.00038 20.1 0.5 0.00079 19.1 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 AEO64970.1 - 0.022 13.6 0.3 0.043 12.6 0.1 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.1 AEO64970.1 - 0.054 13.4 2.5 0.18 11.7 0.9 2.2 2 1 0 2 2 2 0 NADH(P)-binding NmrA PF05368.8 AEO64970.1 - 0.11 11.7 1.2 0.65 9.2 0.4 2.2 2 1 0 2 2 2 0 NmrA-like family DUF1815 PF08844.5 AEO64970.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) ADH_N PF08240.7 AEO64971.1 - 1.2e-29 102.2 0.4 2.4e-29 101.2 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO64971.1 - 8.7e-15 54.4 0.4 1.8e-14 53.4 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aldo_ket_red PF00248.16 AEO64972.1 - 6.8e-53 179.3 0.0 8.5e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SNARE PF05739.14 AEO64973.1 - 1.1e-17 63.4 0.8 1.1e-17 63.4 0.6 2.9 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 AEO64973.1 - 5e-13 49.1 0.2 5e-13 49.1 0.2 2.5 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 AEO64973.1 - 0.0073 15.8 1.4 0.0073 15.8 1.0 2.1 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 AEO64973.1 - 0.051 13.3 1.5 2 8.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 AEO64973.1 - 0.1 12.7 2.3 1.3 9.2 0.1 2.7 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ApoLp-III PF07464.6 AEO64973.1 - 0.11 12.5 2.6 5.2 7.0 0.1 2.5 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Spc7 PF08317.6 AEO64973.1 - 0.21 10.1 6.4 0.081 11.5 0.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Sec2p PF06428.6 AEO64976.1 - 1.1e-27 95.8 14.7 1.1e-27 95.8 10.2 2.4 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p zf-Di19 PF05605.7 AEO64976.1 - 0.015 15.3 0.4 0.029 14.5 0.3 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding FUSC PF04632.7 AEO64976.1 - 0.21 9.9 9.0 0.34 9.2 6.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3584 PF12128.3 AEO64976.1 - 6.9 3.8 25.8 9.7 3.3 17.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PMT PF02366.13 AEO64977.1 - 6e-73 245.2 18.8 1.2e-72 244.1 13.0 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 AEO64977.1 - 6.9e-56 188.8 0.0 1.1e-55 188.1 0.0 1.3 1 0 0 1 1 1 1 MIR domain PRP21_like_P PF12230.3 AEO64978.1 - 8.1e-59 198.8 23.5 5.1e-58 196.2 16.3 2.0 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 AEO64978.1 - 9e-36 121.3 0.5 7.7e-17 60.6 0.0 2.4 2 0 0 2 2 2 2 Surp module PX PF00787.19 AEO64979.1 - 3.6e-24 84.7 0.0 4.6e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.22 AEO64980.1 - 5.6e-78 256.7 1.5 1.9e-25 88.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_6 PF14259.1 AEO64981.1 - 7.9e-07 28.9 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ARPC4 PF05856.7 AEO64982.1 - 1.2e-76 255.8 3.8 1.3e-76 255.7 2.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.24 AEO64983.1 - 4.3e-56 189.9 0.0 5.3e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO64983.1 - 2.8e-21 76.2 0.0 7.9e-21 74.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 AEO64983.1 - 3.3e-11 42.4 0.2 6.6e-11 41.4 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF3510 PF12022.3 AEO64983.1 - 0.25 11.4 1.8 20 5.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Vfa1 PF08432.5 AEO64983.1 - 1.6 8.7 12.5 2.9 7.8 8.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4140 PF13600.1 AEO64984.1 - 0.042 14.2 2.4 0.042 14.2 1.6 1.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2162 PF09930.4 AEO64984.1 - 0.078 12.1 0.1 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Predicted transporter (DUF2162) DUF2674 PF10879.3 AEO64984.1 - 0.08 12.6 0.2 0.15 11.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2674) FTR1 PF03239.9 AEO64984.1 - 0.13 11.2 0.2 0.13 11.1 0.2 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family NAM-associated PF14303.1 AEO64984.1 - 0.2 11.9 3.2 0.26 11.5 2.3 1.3 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF2077 PF09850.4 AEO64984.1 - 0.42 9.9 3.6 0.12 11.7 0.5 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) CR6_interact PF10147.4 AEO64984.1 - 2 7.6 7.6 0.21 10.8 2.1 1.6 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 His_Phos_1 PF00300.17 AEO64985.1 - 2.3e-30 105.7 0.0 2.7e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Methyltransf_23 PF13489.1 AEO64986.1 - 1.3e-16 60.7 0.1 1.9e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO64986.1 - 7e-13 48.8 0.0 1.3e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO64986.1 - 1.8e-12 47.8 0.0 3.9e-12 46.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO64986.1 - 1.1e-11 44.5 0.0 2.2e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO64986.1 - 8.1e-10 39.0 0.0 1.8e-09 37.9 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO64986.1 - 6.1e-09 36.1 0.0 1.7e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO64986.1 - 5.1e-07 29.0 0.0 1.1e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AEO64986.1 - 1.3e-06 28.4 1.7 1.7e-06 28.0 0.5 1.7 2 1 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 AEO64986.1 - 0.0014 17.7 0.0 0.0031 16.6 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 AEO64986.1 - 0.0026 17.4 0.0 0.0066 16.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 AEO64986.1 - 0.011 15.1 0.2 0.023 14.0 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_19 PF04672.7 AEO64986.1 - 0.014 14.6 0.0 0.03 13.6 0.0 1.4 2 0 0 2 2 2 0 S-adenosyl methyltransferase Zn_clus PF00172.13 AEO64987.1 - 7.5e-08 32.1 8.4 1.2e-07 31.5 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GAT PF03127.9 AEO64988.1 - 2.8e-18 65.7 0.2 6.3e-18 64.6 0.1 1.6 1 0 0 1 1 1 1 GAT domain UBA_4 PF14555.1 AEO64989.1 - 1.5e-10 40.4 0.0 3.3e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 AEO64989.1 - 0.0003 20.7 0.0 0.00081 19.4 0.0 1.7 1 0 0 1 1 1 1 UBX domain SUFU_C PF12470.3 AEO64989.1 - 0.041 13.4 0.1 0.066 12.8 0.1 1.3 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain NYD-SP28 PF14772.1 AEO64989.1 - 0.57 10.2 11.8 0.53 10.3 6.3 2.1 2 0 0 2 2 2 0 Sperm tail PV-1 PF06637.6 AEO64989.1 - 4.8 5.6 9.3 7.2 5.0 6.4 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Acetyltransf_6 PF13480.1 AEO64989.1 - 5.1 7.0 11.5 17 5.3 5.5 2.8 3 1 0 3 3 3 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 AEO64990.1 - 1.5e-05 24.3 0.0 2.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO64990.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase PTCB-BRCT PF12738.2 AEO64990.1 - 0.094 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain LSM PF01423.17 AEO64991.1 - 4.3e-18 64.6 0.2 5.6e-18 64.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain SET PF00856.23 AEO64992.1 - 1.6e-20 74.0 0.9 7.3e-20 71.8 0.6 2.3 1 0 0 1 1 1 1 SET domain Rep_fac-A_C PF08646.5 AEO64993.1 - 0.038 13.6 1.8 0.041 13.5 1.3 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain gp32 PF08804.5 AEO64993.1 - 0.17 12.0 0.7 0.19 11.8 0.5 1.2 1 0 0 1 1 1 0 gp32 DNA binding protein like PHD PF00628.24 AEO64993.1 - 4.6 7.0 10.5 1.1 9.0 0.7 2.3 1 1 1 2 2 2 0 PHD-finger zf-B_box PF00643.19 AEO64993.1 - 7.2 6.6 10.0 20 5.1 7.0 1.8 1 1 0 1 1 1 0 B-box zinc finger zf-DHHC PF01529.15 AEO64994.1 - 3.5e-30 104.6 1.5 3.5e-30 104.6 1.0 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF2079 PF09852.4 AEO64994.1 - 0.13 10.9 3.0 0.065 11.9 0.3 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2079) DUF2177 PF09945.4 AEO64994.1 - 1.6 8.7 7.1 0.16 11.9 1.2 1.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2177) DUF485 PF04341.7 AEO64994.1 - 5.6 6.7 8.2 19 5.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF485 IMS PF00817.15 AEO64995.1 - 4.4e-33 114.1 0.0 7.4e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 AEO64995.1 - 2.3e-15 56.6 0.0 4.6e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 AEO64995.1 - 0.0022 17.9 0.0 0.0049 16.8 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif IBN_N PF03810.14 AEO64998.1 - 1.2e-13 50.8 3.4 9.2e-10 38.3 0.0 4.7 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.5 AEO64998.1 - 1.4e-07 30.4 0.2 3.2e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.7 AEO64998.1 - 2.9e-06 27.2 3.1 0.00017 21.5 0.2 4.2 4 0 0 4 4 4 1 Exportin 1-like protein DUF2435 PF10363.4 AEO64998.1 - 0.019 14.8 0.3 0.061 13.2 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) HEAT_2 PF13646.1 AEO64998.1 - 0.15 12.3 10.1 2.3 8.5 0.1 3.9 5 0 0 5 5 5 0 HEAT repeats Pkinase PF00069.20 AEO64999.1 - 1.4e-55 188.2 0.0 2e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO64999.1 - 2.7e-25 88.9 0.0 7.6e-25 87.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO64999.1 - 0.054 12.4 0.1 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Acyl-CoA_dh_2 PF08028.6 AEO65000.1 - 0.13 12.4 4.9 0.066 13.4 1.6 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain ISN1 PF06437.6 AEO65001.1 - 3.9e-191 635.1 0.0 4.4e-191 634.9 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase PV-1 PF06637.6 AEO65001.1 - 0.17 10.4 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF2404 PF10296.4 AEO65003.1 - 2.8e-33 113.9 0.0 1.9e-32 111.2 0.0 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 AEO65003.1 - 0.1 12.7 0.0 0.4 10.9 0.0 2.0 1 0 0 1 1 1 0 PH domain Ribosomal_L21e PF01157.13 AEO65004.1 - 1.3e-40 137.1 5.5 1.8e-40 136.7 3.5 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e DUF3865 PF12981.2 AEO65004.1 - 0.061 13.1 0.1 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) Ribosomal_S4 PF00163.14 AEO65005.1 - 3.6e-27 94.5 0.8 3.6e-27 94.5 0.6 2.1 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 AEO65005.1 - 4.7e-14 51.5 1.5 4.7e-14 51.5 1.1 2.2 3 0 0 3 3 3 1 S4 domain Slu7 PF11708.3 AEO65006.1 - 1.8e-69 234.1 13.0 2.4e-69 233.7 9.0 1.1 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 AEO65006.1 - 0.00025 20.6 0.1 0.00047 19.7 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 AEO65006.1 - 0.0019 18.0 3.3 0.0033 17.2 2.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 AEO65006.1 - 0.051 13.2 3.0 0.12 12.0 2.1 1.6 1 0 0 1 1 1 0 Zinc knuckle DNA_pol_B PF00136.16 AEO65007.1 - 5.2e-95 318.9 0.0 7.6e-95 318.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 AEO65007.1 - 9.8e-22 77.2 0.0 5.4e-12 45.2 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 AEO65007.1 - 4e-19 68.3 1.5 4e-19 68.3 1.0 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Mcp5_PH PF12814.2 AEO65008.1 - 1e-43 148.1 0.9 2.5e-43 146.9 0.0 2.1 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology DUF1202 PF06717.6 AEO65008.1 - 5.1 6.2 7.8 0.26 10.5 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1202) zf-CCCH PF00642.19 AEO65009.1 - 4.1e-08 32.7 2.0 8.5e-08 31.6 1.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 AEO65009.1 - 1.1e-07 31.4 3.9 1.7e-07 30.7 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO65009.1 - 4.1e-07 29.8 8.6 7.1e-07 29.1 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO65009.1 - 5.4e-07 29.2 6.2 8.8e-07 28.5 4.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AEO65009.1 - 2.5e-06 27.0 6.6 4.3e-06 26.2 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO65009.1 - 6.3e-06 25.9 6.0 9.9e-06 25.2 4.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 AEO65009.1 - 0.005 16.5 1.2 0.013 15.2 0.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AEO65009.1 - 0.015 15.1 7.0 0.033 14.0 4.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Harakiri PF15196.1 AEO65009.1 - 0.15 12.3 4.7 0.18 12.1 1.2 2.3 2 0 0 2 2 2 0 Activator of apoptosis harakiri Cript PF10235.4 AEO65009.1 - 3.7 7.9 5.8 2.4 8.5 1.5 2.4 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Autophagy_N PF03986.8 AEO65010.1 - 9.1e-45 152.0 0.6 1.2e-44 151.6 0.0 1.5 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 AEO65010.1 - 1.5e-23 82.7 0.6 1.5e-22 79.5 0.2 2.3 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 AEO65010.1 - 1.8e-14 52.4 0.5 3.3e-14 51.6 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal ANTH PF07651.11 AEO65011.1 - 4.1e-80 268.4 0.2 1.8e-79 266.3 0.0 2.2 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 AEO65011.1 - 1.2e-63 213.5 8.8 1.2e-63 213.5 6.1 5.1 6 1 0 6 6 6 1 I/LWEQ domain ENTH PF01417.15 AEO65011.1 - 0.00053 19.8 0.0 0.0018 18.1 0.0 2.0 1 0 0 1 1 1 1 ENTH domain TP6A_N PF04406.9 AEO65011.1 - 0.0064 16.1 0.0 4.1 7.1 0.0 3.0 2 0 0 2 2 2 2 Type IIB DNA topoisomerase Reo_sigmaC PF04582.7 AEO65011.1 - 1.7 7.7 17.2 0.055 12.6 0.3 4.0 3 1 1 5 5 5 0 Reovirus sigma C capsid protein MAT_Alpha1 PF04769.7 AEO65012.1 - 6e-57 192.2 0.0 9.2e-57 191.6 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG_box PF00505.14 AEO65014.1 - 1.2e-17 63.8 0.0 1.9e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box Exo_endo_phos_2 PF14529.1 AEO65015.1 - 8.1e-17 60.9 0.0 8.6e-16 57.6 0.0 2.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 AEO65015.1 - 1.3e-16 61.2 0.0 2.4e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 AEO65015.1 - 2.8e-05 23.9 1.1 9.9e-05 22.1 0.8 2.0 1 0 0 1 1 1 1 GRF zinc finger COX6A PF02046.10 AEO65016.1 - 1.7e-38 131.0 2.0 1.9e-38 130.9 1.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF2984 PF11203.3 AEO65016.1 - 0.086 12.9 2.3 0.14 12.3 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2984) Apc5 PF12862.2 AEO65017.1 - 1.7e-30 104.7 2.3 9.3e-30 102.3 0.8 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_14 PF13428.1 AEO65017.1 - 0.011 16.3 15.4 2.8 8.8 0.1 7.1 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 AEO65017.1 - 0.029 14.7 3.2 18 6.1 0.3 4.8 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RING_2 PF13639.1 AEO65018.1 - 4.5e-14 52.0 5.7 7.2e-14 51.3 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 AEO65018.1 - 4.1e-12 45.6 0.0 8e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 AEO65018.1 - 3.9e-09 36.3 5.2 6.3e-09 35.7 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO65018.1 - 7.9e-09 35.4 1.9 1.5e-08 34.5 1.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 AEO65018.1 - 3.3e-08 33.0 3.0 5.3e-08 32.3 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO65018.1 - 8.7e-08 31.7 4.0 1.3e-07 31.1 2.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO65018.1 - 2.4e-07 30.3 2.8 3.7e-07 29.7 2.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 AEO65018.1 - 0.0012 18.6 1.0 0.0022 17.7 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 AEO65018.1 - 0.028 14.1 2.5 0.065 12.9 1.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 AEO65018.1 - 0.087 12.8 2.3 0.28 11.1 1.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 AEO65018.1 - 0.098 12.7 3.8 0.2 11.7 2.6 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 AEO65018.1 - 0.15 11.9 3.4 0.54 10.1 2.5 1.8 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Baculo_RING PF05883.6 AEO65018.1 - 0.3 10.9 0.1 0.5 10.2 0.1 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 AEO65018.1 - 0.49 10.0 3.0 0.88 9.2 2.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 AEO65018.1 - 1.9 8.5 3.6 3.5 7.7 2.5 1.4 1 0 0 1 1 1 0 RING-like domain tRNA-synt_1 PF00133.17 AEO65019.1 - 1.5e-225 749.7 0.0 1.4e-224 746.6 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AEO65019.1 - 9.4e-36 122.8 0.0 2.4e-35 121.5 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AEO65019.1 - 8.6e-17 60.8 0.4 0.00023 19.9 0.0 4.8 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 AEO65019.1 - 2.9e-10 39.7 5.8 7e-08 31.9 0.0 3.1 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 AEO65019.1 - 0.00065 18.9 0.0 0.014 14.5 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.4 AEO65019.1 - 0.0039 17.2 4.5 0.0039 17.2 3.2 2.8 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm DOR PF14839.1 AEO65019.1 - 1 9.0 7.6 2.3 7.8 5.2 1.5 1 0 0 1 1 1 0 DOR family Ribosomal_L37e PF01907.14 AEO65020.1 - 1.2e-25 89.0 13.3 1.9e-25 88.3 9.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 AEO65020.1 - 0.00067 19.4 2.1 0.0012 18.6 1.4 1.4 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 AEO65020.1 - 0.0079 15.8 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 SelR domain Ogr_Delta PF04606.7 AEO65020.1 - 0.34 10.6 4.8 2.2 7.9 0.2 3.2 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zf-ribbon_3 PF13248.1 AEO65020.1 - 0.41 9.9 3.3 1.2 8.4 2.3 1.8 1 1 0 1 1 1 0 zinc-ribbon domain DUF2348 PF09807.4 AEO65021.1 - 8.3e-06 25.0 0.0 0.0052 15.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) AAA_25 PF13481.1 AEO65021.1 - 0.072 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Phostensin_N PF13916.1 AEO65021.1 - 0.71 9.8 5.0 0.25 11.3 0.9 2.2 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal MFS_1 PF07690.11 AEO65022.1 - 3.3e-40 137.8 37.0 6.1e-29 100.8 10.8 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO65022.1 - 1.4e-10 40.3 14.6 1.4e-10 40.3 10.1 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter Thioredoxin PF00085.15 AEO65023.1 - 2.1e-06 27.3 0.0 2.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 AEO65023.1 - 0.013 15.0 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.1 AEO65023.1 - 0.065 12.8 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.1 AEO65023.1 - 0.12 12.5 0.0 2.4 8.4 0.0 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain AAA_13 PF13166.1 AEO65024.1 - 0.0086 14.5 5.6 0.022 13.2 0.2 2.1 1 1 1 2 2 2 1 AAA domain Spc7 PF08317.6 AEO65024.1 - 0.027 13.1 3.1 0.12 10.9 1.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3726 PF12525.3 AEO65024.1 - 0.048 13.4 0.8 0.73 9.6 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3726) Cluap1 PF10234.4 AEO65024.1 - 0.049 12.8 7.9 0.57 9.3 0.9 2.6 1 1 1 2 2 2 0 Clusterin-associated protein-1 HALZ PF02183.13 AEO65024.1 - 0.47 10.2 2.9 2.6 7.8 0.1 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper SlyX PF04102.7 AEO65024.1 - 0.47 10.8 6.4 1.2 9.6 0.5 3.5 1 1 3 4 4 4 0 SlyX ADIP PF11559.3 AEO65024.1 - 0.65 9.8 11.4 0.47 10.3 1.1 3.4 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.7 AEO65024.1 - 0.85 9.3 6.3 0.39 10.4 0.5 2.6 2 1 0 3 3 3 0 Plant protein of unknown function (DUF641) COG2 PF06148.6 AEO65024.1 - 1.9 8.3 6.4 25 4.7 1.5 2.9 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.4 AEO65024.1 - 2.4 7.9 13.3 2.4 7.9 2.9 2.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 AEO65024.1 - 3.2 7.3 9.4 7.8 6.0 2.4 2.2 1 1 0 2 2 2 0 IncA protein DivIC PF04977.10 AEO65024.1 - 4.1 6.9 15.1 5.1 6.6 0.2 3.7 3 0 0 3 3 3 0 Septum formation initiator Pox_A_type_inc PF04508.7 AEO65024.1 - 4.6 7.2 7.0 37 4.4 0.2 3.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat TMF_DNA_bd PF12329.3 AEO65024.1 - 4.8 7.0 19.2 0.33 10.7 0.8 3.9 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding JmjC PF02373.17 AEO65025.1 - 9e-18 64.5 0.0 1.6e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase SET PF00856.23 AEO65025.1 - 7.6e-09 36.0 0.0 2.2e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 SET domain HTH_31 PF13560.1 AEO65026.1 - 0.0046 17.1 0.7 0.0083 16.3 0.5 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain CPSase_L_D3 PF02787.14 AEO65026.1 - 0.06 13.1 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_3 PF01381.17 AEO65026.1 - 0.069 13.0 0.3 0.16 11.8 0.2 1.7 1 1 0 1 1 1 0 Helix-turn-helix CIA30 PF08547.7 AEO65027.1 - 3.8e-45 153.5 0.0 6.2e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) RRM_1 PF00076.17 AEO65028.1 - 5.8e-20 70.6 0.1 2.2e-10 40.0 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO65028.1 - 1.3e-16 60.2 0.5 4.9e-08 32.8 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO65028.1 - 2.4e-13 49.6 0.1 2.6e-06 27.1 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SSF PF00474.12 AEO65029.1 - 4.1e-08 32.2 26.4 7.3e-07 28.1 18.3 2.4 1 1 0 1 1 1 1 Sodium:solute symporter family Tim44 PF04280.10 AEO65030.1 - 9.1e-07 28.9 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.6 AEO65030.1 - 2.9e-05 23.0 0.0 3.8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 MBA1-like protein EOS1 PF12326.3 AEO65031.1 - 1.4e-28 99.4 10.8 1.2e-23 83.3 3.1 2.2 1 1 1 2 2 2 2 N-glycosylation protein DUF4396 PF14342.1 AEO65031.1 - 0.04 14.0 1.6 0.41 10.7 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) DUF2142 PF09913.4 AEO65031.1 - 0.12 10.9 4.9 0.16 10.5 3.4 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2142) SUI1 PF01253.17 AEO65032.1 - 3.2e-29 100.5 3.0 4.8e-29 100.0 2.1 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Ocnus PF05005.10 AEO65032.1 - 0.077 12.8 0.8 0.12 12.3 0.2 1.5 2 0 0 2 2 2 0 Janus/Ocnus family (Ocnus) DUF2575 PF10837.3 AEO65032.1 - 0.078 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) Cas_Csa5 PF09702.5 AEO65032.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) AdoMet_MTase PF07757.8 AEO65033.1 - 4e-38 129.9 0.0 7e-38 129.1 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 AEO65033.1 - 0.0019 17.9 0.0 0.0043 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 AEO65033.1 - 0.021 14.4 0.2 0.27 10.9 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 AEO65033.1 - 0.041 14.4 0.0 0.078 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Dioxygenase_C PF00775.16 AEO65034.1 - 7.9e-38 129.5 0.0 8.6e-38 129.4 0.0 1.0 1 0 0 1 1 1 1 Dioxygenase CarboxypepD_reg PF13620.1 AEO65034.1 - 2.9e-06 27.2 0.0 6.4e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.11 AEO65034.1 - 0.017 14.9 0.0 0.029 14.2 0.0 1.4 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 1) DUF824 PF05688.6 AEO65034.1 - 0.025 14.2 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) DUF4480 PF13715.1 AEO65034.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4480) TRP PF06011.7 AEO65036.1 - 2.5e-98 329.5 12.4 3.3e-98 329.1 8.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 AEO65036.1 - 3.3e-25 88.7 0.0 4.9e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Protocadherin PF08374.6 AEO65036.1 - 0.51 9.9 1.5 42 3.6 1.6 2.2 2 0 0 2 2 2 0 Protocadherin ATP-sulfurylase PF01747.12 AEO65038.1 - 8.7e-89 296.4 0.1 1.2e-88 296.0 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 AEO65038.1 - 2.1e-59 199.7 0.0 3.1e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 AEO65038.1 - 1.5e-52 177.2 0.0 2.7e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.5 AEO65038.1 - 0.084 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CPT PF07931.7 AEO65038.1 - 0.14 11.7 0.0 0.6 9.7 0.0 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Nucleoplasmin PF03066.10 AEO65039.1 - 0.26 10.8 5.0 0.23 10.9 3.5 1.1 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 AEO65039.1 - 0.47 10.7 3.6 0.48 10.7 2.5 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 AEO65039.1 - 1.8 8.8 6.5 1.9 8.7 4.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain EI24 PF07264.6 AEO65040.1 - 5.6e-07 29.2 5.4 1.6e-06 27.7 3.6 1.9 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) UPF0016 PF01169.14 AEO65041.1 - 2.4e-43 146.1 26.4 2.8e-22 78.6 5.2 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 vMSA PF00695.14 AEO65041.1 - 0.037 13.2 1.6 0.43 9.7 0.2 2.1 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus PmbA_TldD PF01523.11 AEO65042.1 - 0.22 10.7 0.8 0.39 9.9 0.5 1.3 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Adaptin_N PF01602.15 AEO65043.1 - 4.4e-116 388.2 0.4 5.6e-116 387.9 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 AEO65043.1 - 8.2e-58 194.5 2.5 1.7e-57 193.5 1.7 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 AEO65043.1 - 1.5e-14 53.9 1.4 2.6e-05 24.4 0.1 5.8 2 1 4 6 6 6 5 HEAT repeats HEAT_PBS PF03130.11 AEO65043.1 - 0.00034 20.8 0.0 0.98 10.0 0.0 4.3 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat CLASP_N PF12348.3 AEO65043.1 - 0.0022 17.4 1.8 0.024 14.0 0.0 2.8 2 1 1 3 3 3 1 CLASP N terminal HEAT_EZ PF13513.1 AEO65043.1 - 0.17 12.4 3.2 0.8 10.2 0.7 3.0 2 0 0 2 2 2 0 HEAT-like repeat HEAT PF02985.17 AEO65043.1 - 0.18 11.9 7.3 2 8.7 0.2 4.4 4 0 0 4 4 4 0 HEAT repeat CDP-OH_P_transf PF01066.16 AEO65044.1 - 3.9e-16 59.1 3.6 3.9e-16 59.1 2.5 2.9 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase bZIP_1 PF00170.16 AEO65045.1 - 7.4e-08 32.2 15.1 1.3e-07 31.5 10.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AEO65045.1 - 0.016 15.0 17.7 0.087 12.6 11.0 2.2 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.12 AEO65045.1 - 0.022 15.0 14.3 0.033 14.4 9.9 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF972 PF06156.8 AEO65045.1 - 0.041 14.2 1.6 0.084 13.2 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) PA26 PF04636.8 AEO65045.1 - 0.15 10.6 1.9 0.19 10.3 1.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) V_ATPase_I PF01496.14 AEO65045.1 - 0.17 9.7 0.6 0.2 9.4 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.9 AEO65045.1 - 0.25 10.9 4.1 0.37 10.3 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PAT1 PF09770.4 AEO65045.1 - 0.3 9.2 13.4 0.39 8.8 9.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IncA PF04156.9 AEO65045.1 - 0.67 9.5 6.3 1 8.9 4.4 1.2 1 0 0 1 1 1 0 IncA protein ADIP PF11559.3 AEO65045.1 - 0.76 9.6 11.2 5.1 6.9 8.6 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.3 AEO65045.1 - 3 5.0 12.4 3.8 4.6 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NUP50 PF08911.6 AEO65046.1 - 0.031 14.6 3.4 0.095 13.0 0.3 2.6 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) SUR7 PF06687.7 AEO65047.1 - 1.5e-26 93.2 13.9 1.9e-26 92.9 9.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family 7TM_GPCR_Srd PF10317.4 AEO65047.1 - 0.14 11.0 5.0 0.25 10.2 3.4 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd NfeD PF01957.13 AEO65047.1 - 0.39 10.8 9.3 0.023 14.8 1.8 2.2 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding ABC1 PF03109.11 AEO65048.1 - 2.2e-08 34.1 0.0 5.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 AEO65048.1 - 0.065 12.9 0.1 0.17 11.5 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Septin PF00735.13 AEO65049.1 - 9.7e-31 106.8 0.0 9.5e-12 44.5 0.0 3.2 3 0 0 3 3 3 3 Septin AAA_23 PF13476.1 AEO65049.1 - 0.002 18.4 0.0 0.0043 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 AEO65049.1 - 0.0028 17.1 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family G-alpha PF00503.15 AEO65049.1 - 0.011 14.4 0.0 0.016 13.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.18 AEO65049.1 - 0.011 15.7 0.1 0.029 14.3 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.1 AEO65049.1 - 0.011 16.5 0.0 0.029 15.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 AEO65049.1 - 0.018 15.5 0.0 0.044 14.2 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 AEO65049.1 - 0.067 13.0 0.1 0.26 11.1 0.1 2.0 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 AEO65049.1 - 0.1 12.8 0.2 0.35 11.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 AEO65049.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Zeta_toxin PF06414.7 AEO65049.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.9 AEO65049.1 - 0.15 11.7 0.6 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B zf-MYND PF01753.13 AEO65050.1 - 0.042 13.7 17.4 0.41 10.5 0.1 3.4 3 0 0 3 3 3 0 MYND finger HisKA PF00512.20 AEO65050.1 - 0.077 12.9 3.1 0.2 11.6 0.0 3.2 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain Ecl1 PF12855.2 AEO65050.1 - 0.62 9.3 7.9 1.9 7.8 2.1 2.7 2 0 0 2 2 2 0 Life-span regulatory factor FliD_N PF02465.13 AEO65050.1 - 9.1 6.7 8.7 1.9 8.9 1.1 2.7 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus MAGE PF01454.14 AEO65051.1 - 9.3e-47 158.8 0.0 1.2e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 MAGE family LZ_Tnp_IS66 PF13007.2 AEO65051.1 - 0.0088 16.6 3.7 0.0088 16.6 2.6 2.4 2 0 0 2 2 2 1 Transposase C of IS166 homeodomain DUF4572 PF15139.1 AEO65051.1 - 0.036 13.9 0.1 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) SLS PF14611.1 AEO65052.1 - 9e-42 142.8 0.2 2.9e-41 141.1 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator GTP_EFTU PF00009.22 AEO65053.1 - 1.5e-57 194.0 0.0 2.1e-57 193.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AEO65053.1 - 1.2e-36 124.8 0.0 3e-36 123.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AEO65053.1 - 2e-17 63.0 1.0 2e-17 63.0 0.7 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 AEO65053.1 - 0.00016 21.2 0.2 0.00042 19.8 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 AEO65053.1 - 0.0013 18.6 0.2 0.0036 17.2 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase HAD PF12710.2 AEO65054.1 - 2.8e-18 66.7 0.0 4.2e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AEO65054.1 - 4.7e-11 43.5 0.8 3.2e-09 37.5 0.5 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AEO65054.1 - 5.5e-09 35.9 0.6 3.8e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AEO65054.1 - 9.7e-07 29.1 0.0 3.3e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 AEO65054.1 - 0.0015 17.6 0.1 0.0021 17.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) DUF809 PF05663.6 AEO65054.1 - 0.014 15.3 0.1 0.025 14.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF809) DUF4620 PF15399.1 AEO65054.1 - 0.027 14.6 1.9 0.067 13.3 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) TIP39 PF14980.1 AEO65054.1 - 0.089 12.4 0.1 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 TIP39 peptide Put_Phosphatase PF06888.7 AEO65054.1 - 0.092 11.8 0.1 3.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase Acid_PPase PF12689.2 AEO65054.1 - 0.14 11.7 0.0 0.35 10.4 0.0 1.6 2 0 0 2 2 2 0 Acid Phosphatase PAPS_reduct PF01507.14 AEO65055.1 - 7e-44 149.6 0.0 9.1e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family TYW3 PF02676.9 AEO65056.1 - 4.9e-62 208.7 0.0 9.9e-62 207.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase TYW3 Fasciclin PF02469.17 AEO65056.1 - 5.9e-45 152.4 5.5 2.3e-25 89.0 0.3 2.3 2 0 0 2 2 2 2 Fasciclin domain DUF1690 PF07956.6 AEO65057.1 - 4.3e-33 114.2 0.7 5e-33 114.0 0.5 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) ApoL PF05461.6 AEO65057.1 - 0.013 14.7 0.5 0.016 14.4 0.3 1.2 1 0 0 1 1 1 0 Apolipoprotein L OmpH PF03938.9 AEO65057.1 - 0.46 10.4 5.1 0.63 9.9 3.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FUSC PF04632.7 AEO65057.1 - 0.51 8.7 4.5 0.59 8.4 3.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HSCB_C PF07743.8 AEO65057.1 - 0.81 10.1 8.8 7.4 7.1 3.0 3.1 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain BLOC1_2 PF10046.4 AEO65057.1 - 1.6 8.8 6.0 0.61 10.2 0.8 2.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ferric_reduct PF01794.14 AEO65058.1 - 1.9e-20 73.1 9.3 1.9e-20 73.1 6.5 2.3 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 AEO65058.1 - 3.2e-19 69.3 0.0 2.2e-17 63.4 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 AEO65058.1 - 3e-11 43.1 0.0 2.5e-10 40.1 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain HMGL-like PF00682.14 AEO65059.1 - 7.6e-66 222.1 0.0 1.3e-65 221.4 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 AEO65059.1 - 6.3e-24 84.2 0.0 2e-23 82.6 0.0 1.8 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain HEAT_2 PF13646.1 AEO65060.1 - 5.5e-14 52.2 16.8 2.7e-05 24.3 0.0 7.9 2 1 7 9 9 9 7 HEAT repeats HEAT PF02985.17 AEO65060.1 - 9.6e-14 50.1 10.6 0.00078 19.3 0.0 10.4 12 0 0 12 12 12 3 HEAT repeat HEAT_EZ PF13513.1 AEO65060.1 - 3.6e-12 46.3 12.7 1.4e-06 28.5 0.0 8.3 7 2 2 9 9 9 1 HEAT-like repeat IBN_N PF03810.14 AEO65060.1 - 5e-08 32.7 5.2 1.5e-07 31.2 1.5 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 AEO65060.1 - 0.0014 17.9 3.7 2.3 7.5 0.1 4.6 4 2 2 6 6 6 2 CLASP N terminal Cse1 PF08506.5 AEO65060.1 - 0.0059 15.2 0.0 0.13 10.7 0.1 2.9 3 0 0 3 3 3 1 Cse1 Arm PF00514.18 AEO65060.1 - 0.0061 16.3 0.3 37 4.3 0.0 5.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF1548 PF07579.6 AEO65060.1 - 0.54 10.3 2.4 16 5.5 0.0 3.8 4 1 0 4 4 4 0 Domain of Unknown Function (DUF1548) Troponin-I_N PF11636.3 AEO65061.1 - 3.1 7.5 21.2 0.29 10.8 3.2 2.8 3 0 0 3 3 3 0 Troponin I residues 1-32 Fungal_trans PF04082.13 AEO65062.1 - 6.8e-11 41.5 0.1 1.2e-10 40.6 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_60s PF00428.14 AEO65062.1 - 8 6.9 14.0 7.8 6.9 8.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Complex1_LYR_1 PF13232.1 AEO65063.1 - 7.1e-25 86.9 3.2 9.3e-25 86.6 2.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 AEO65063.1 - 2.5e-23 81.6 3.9 3.5e-23 81.1 2.7 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 AEO65063.1 - 0.038 14.4 3.2 0.077 13.4 2.2 1.5 1 1 1 2 2 2 0 Complex1_LYR-like Toxin_43 PF15604.1 AEO65063.1 - 0.069 13.1 2.0 0.077 13.0 1.4 1.1 1 0 0 1 1 1 0 Putative toxin 43 zf-DHHC PF01529.15 AEO65065.1 - 3.9e-40 137.0 0.4 8.8e-40 135.9 0.3 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase Yip1 PF04893.12 AEO65065.1 - 0.0014 18.1 4.6 0.0019 17.7 0.1 2.1 2 0 0 2 2 2 1 Yip1 domain CBFD_NFYB_HMF PF00808.18 AEO65067.1 - 9e-17 60.8 0.4 1.7e-16 59.9 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AEO65067.1 - 8.8e-06 25.7 0.0 1.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Spidroin_MaSp PF11260.3 AEO65067.1 - 0.023 14.7 0.8 0.042 13.9 0.4 1.5 1 1 1 2 2 2 0 Major ampullate spidroin 1 and 2 adh_short PF00106.20 AEO65068.1 - 1.6e-33 115.9 4.3 2.2e-33 115.5 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO65068.1 - 1.2e-18 67.7 0.2 1.5e-18 67.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO65068.1 - 2.3e-15 56.7 3.0 3.3e-15 56.1 2.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO65068.1 - 3.5e-07 30.4 0.4 6.1e-07 29.6 0.3 1.4 1 1 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 AEO65068.1 - 0.0016 18.8 0.5 0.0048 17.2 0.0 1.9 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 AEO65068.1 - 0.0025 17.2 0.2 0.0061 16.0 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CoA_binding_2 PF13380.1 AEO65068.1 - 0.0075 16.4 0.3 0.066 13.3 0.1 2.3 1 1 0 2 2 2 1 CoA binding domain ADH_zinc_N PF00107.21 AEO65068.1 - 0.01 15.3 0.2 0.027 14.0 0.1 1.9 2 1 0 2 2 2 0 Zinc-binding dehydrogenase TrkA_N PF02254.13 AEO65068.1 - 0.024 14.6 0.0 0.082 12.9 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain HAD PF12710.2 AEO65068.1 - 0.087 12.9 0.4 7.8 6.6 0.0 2.6 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase 3HCDH_N PF02737.13 AEO65068.1 - 0.11 12.1 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PP2C_2 PF13672.1 AEO65068.1 - 0.13 11.6 0.3 0.22 10.9 0.2 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C DAO PF01266.19 AEO65069.1 - 1.2e-37 129.7 4.1 2e-37 128.9 2.9 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO65069.1 - 1.8e-05 25.0 0.0 0.0036 17.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO65069.1 - 0.00046 20.1 0.1 0.0018 18.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 AEO65069.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 AEO65069.1 - 0.024 14.5 0.0 4 7.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ferric_reduct PF01794.14 AEO65070.1 - 3.6e-15 56.1 7.7 9.5e-15 54.7 5.3 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 AEO65070.1 - 1.2e-14 54.0 0.0 6.4e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 AEO65070.1 - 1.4e-13 51.0 0.0 2.5e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 AEO65070.1 - 9.2e-06 26.1 0.0 0.0029 18.1 0.0 2.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain CAP_N PF01213.14 AEO65070.1 - 0.18 11.0 0.6 0.5 9.6 0.4 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ribosomal_60s PF00428.14 AEO65070.1 - 5.4 7.4 6.5 2.2 8.7 1.7 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein LigB PF02900.13 AEO65071.1 - 7.7e-53 179.2 0.0 8.8e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Abhydrolase_2 PF02230.11 AEO65072.1 - 3.6e-61 206.3 0.0 4.3e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 AEO65072.1 - 7e-12 45.3 0.0 1.7e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO65072.1 - 1.6e-06 28.2 0.3 0.003 17.4 0.5 2.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 AEO65072.1 - 2.6e-06 27.0 0.0 1.6e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 AEO65072.1 - 2e-05 23.8 0.6 0.0017 17.6 0.0 2.6 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 AEO65072.1 - 0.019 14.5 0.0 0.21 11.1 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.13 AEO65072.1 - 0.021 14.0 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Cutinase PF01083.17 AEO65072.1 - 0.13 12.0 0.0 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 Cutinase Abhydrolase_1 PF00561.15 AEO65072.1 - 0.15 11.6 0.1 3.1 7.2 0.1 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold Herpes_LMP2 PF07415.6 AEO65075.1 - 1.8 7.0 5.8 3.2 6.2 4.0 1.4 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein p450 PF00067.17 AEO65076.1 - 7.3e-59 199.4 0.0 9.1e-59 199.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EAF PF09816.4 AEO65077.1 - 6e-22 77.6 0.0 1e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor MSP1_C PF07462.6 AEO65077.1 - 0.36 9.1 1.8 0.54 8.5 1.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DNA_methylase PF00145.12 AEO65078.1 - 6.1e-40 137.3 0.0 2.5e-30 105.7 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase HhH-GPD PF00730.20 AEO65079.1 - 4e-10 39.9 0.0 8.2e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Rubi_NSP_C PF12601.3 AEO65079.1 - 0.036 13.9 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 Rubivirus non-structural protein SEN1_N PF12726.2 AEO65080.1 - 3.3e-195 650.2 1.5 4.2e-195 649.9 1.1 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 AEO65080.1 - 9.3e-69 231.5 0.1 9.3e-69 231.5 0.1 2.3 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 AEO65080.1 - 2.8e-63 212.9 0.0 5e-63 212.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO65080.1 - 1.1e-10 41.1 0.8 4e-10 39.3 0.6 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 AEO65080.1 - 9e-09 35.1 0.2 4.9e-06 26.2 0.1 2.7 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 AEO65080.1 - 4.7e-06 26.1 5.8 0.0021 17.3 0.0 3.9 3 1 1 4 4 4 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 AEO65080.1 - 5.3e-05 22.8 1.4 0.013 15.0 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 AEO65080.1 - 0.019 14.3 0.1 0.081 12.3 0.1 2.1 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 AEO65080.1 - 0.43 10.4 0.0 0.43 10.4 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF904 PF06005.7 AEO65080.1 - 0.99 9.7 8.8 1.1 9.6 0.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Amidase PF01425.16 AEO65082.1 - 2.3e-79 267.3 1.3 3e-79 266.9 0.9 1.1 1 0 0 1 1 1 1 Amidase NAD_synthase PF02540.12 AEO65082.1 - 0.19 10.5 0.1 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Malate_synthase PF01274.17 AEO65083.1 - 3.3e-238 790.9 0.0 3.7e-238 790.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Lyase_1 PF00206.15 AEO65084.1 - 2.3e-110 368.6 0.0 3.4e-110 368.1 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 AEO65084.1 - 2.1e-22 78.9 0.1 4.6e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus Pkinase PF00069.20 AEO65085.1 - 1.7e-74 250.2 0.0 2.6e-74 249.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO65085.1 - 3.5e-37 127.8 0.3 8.2e-35 120.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AEO65085.1 - 1.2e-05 24.4 0.0 2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AEO65085.1 - 0.0014 17.7 0.0 0.0033 16.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO65085.1 - 0.0025 17.5 1.1 0.0054 16.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO65085.1 - 0.0029 17.2 0.2 0.0059 16.2 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase SMC_N PF02463.14 AEO65086.1 - 1.2e-27 96.6 0.0 1.8e-26 92.7 0.0 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AEO65086.1 - 1.3e-12 48.4 21.5 1.3e-12 48.4 14.9 5.5 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 AEO65086.1 - 8.6e-07 29.1 0.0 0.00012 22.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AEO65086.1 - 0.0028 17.1 0.0 0.0055 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 AEO65086.1 - 0.025 13.6 0.1 0.025 13.6 0.0 3.3 2 2 0 2 2 2 0 AAA ATPase domain PilN PF05137.8 AEO65086.1 - 0.063 13.1 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) Glyco_hydro_4 PF02056.11 AEO65086.1 - 0.1 11.9 1.0 1.7 7.8 0.0 3.2 3 0 0 3 3 3 0 Family 4 glycosyl hydrolase AAA_25 PF13481.1 AEO65086.1 - 0.41 10.0 5.4 0.58 9.5 0.0 3.3 2 1 0 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 AEO65086.1 - 3.4 6.7 11.6 9 5.3 0.0 4.0 2 2 1 4 4 4 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 AEO65086.1 - 6.1 7.1 13.8 1.1 9.5 1.6 4.2 2 2 0 2 2 2 0 ABC transporter Glycoprotein_B PF00606.13 AEO65087.1 - 0.0022 16.1 0.7 0.0025 15.9 0.5 1.0 1 0 0 1 1 1 1 Herpesvirus Glycoprotein B ERCC4 PF02732.10 AEO65088.1 - 1.6e-26 92.7 0.0 3.6e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.1 AEO65088.1 - 0.014 15.5 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain WH1 PF00568.18 AEO65090.1 - 5.2e-29 100.1 0.2 7.1e-29 99.7 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 AEO65090.1 - 0.00048 19.6 0.2 0.0011 18.5 0.1 1.6 1 0 0 1 1 1 1 WH2 motif eIF-1a PF01176.14 AEO65091.1 - 6.7e-28 95.8 0.2 9.3e-28 95.4 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DFP PF04127.10 AEO65093.1 - 2.3e-13 50.1 0.0 8.1e-05 22.3 0.0 3.1 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein PTCB-BRCT PF12738.2 AEO65094.1 - 8.9e-12 44.6 0.0 1.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 AEO65094.1 - 2.4e-10 40.4 0.0 3.9e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Nucleo_P87 PF07267.6 AEO65094.1 - 1.1 7.8 6.0 1.4 7.5 4.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Totivirus_coat PF05518.6 AEO65094.1 - 2.6 5.7 6.2 3.6 5.2 4.3 1.1 1 0 0 1 1 1 0 Totivirus coat protein SRP-alpha_N PF04086.8 AEO65094.1 - 6.3 6.0 8.6 25 4.1 6.0 1.7 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal MFS_1 PF07690.11 AEO65095.1 - 9e-41 139.7 46.1 2.1e-38 131.9 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 AEO65095.1 - 0.023 14.4 3.5 0.48 10.2 0.0 2.9 2 0 0 2 2 2 0 MFS_1 like family Glyco_hydro_47 PF01532.15 AEO65097.1 - 2.1e-161 537.5 0.0 2.5e-161 537.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1191 PF06697.7 AEO65098.1 - 0.023 13.5 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) CENP-O PF09496.5 AEO65099.1 - 1.7e-22 79.4 0.0 3e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Pox_A_type_inc PF04508.7 AEO65099.1 - 0.14 11.9 2.2 0.68 9.8 0.2 2.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Acatn PF13000.2 AEO65100.1 - 5.4e-150 500.5 19.4 2.2e-75 254.2 4.7 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DEAD PF00270.24 AEO65101.1 - 1e-42 145.4 0.0 2.5e-42 144.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO65101.1 - 2.8e-20 71.9 1.4 3.6e-20 71.6 0.0 1.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AEO65101.1 - 2.7e-05 23.1 0.0 3.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 AEO65101.1 - 0.036 14.0 0.0 0.094 12.6 0.0 1.7 2 0 0 2 2 2 0 Helicase C-terminal domain DUF1253 PF06862.7 AEO65101.1 - 0.039 12.3 0.1 3.4 5.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) Thioredoxin_8 PF13905.1 AEO65101.1 - 0.084 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Ipi1_N PF12333.3 AEO65102.1 - 1.1e-26 92.7 0.0 2.9e-26 91.4 0.0 1.8 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation Robl_LC7 PF03259.12 AEO65103.1 - 4.7e-10 38.8 0.0 2.5e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Pyrid_oxidase_2 PF13883.1 AEO65105.1 - 5.2e-41 140.2 0.0 1.4e-40 138.7 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ribosomal_S30 PF04758.9 AEO65106.1 - 1.6e-29 101.4 8.0 1.9e-29 101.1 5.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 CorA PF01544.13 AEO65108.1 - 1.7e-13 50.2 1.0 2.7e-13 49.6 0.7 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Sipho_Gp157 PF05565.6 AEO65108.1 - 0.13 11.8 4.0 1.1 8.8 0.4 2.2 2 0 0 2 2 2 0 Siphovirus Gp157 Cyclin PF08613.6 AEO65109.1 - 1.2e-12 48.4 0.0 3e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AEO65109.1 - 0.033 13.7 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain DEAD PF00270.24 AEO65110.1 - 6.8e-38 129.8 0.0 1.1e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO65110.1 - 8.6e-25 86.4 0.0 2.3e-23 81.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO65110.1 - 1.3e-06 28.4 0.0 3.7e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 AEO65110.1 - 0.048 12.7 0.0 0.34 9.9 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Rpr2 PF04032.11 AEO65111.1 - 2e-20 72.4 0.1 3.3e-20 71.7 0.1 1.3 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DASH_Hsk3 PF08227.6 AEO65112.1 - 2.4e-20 72.4 6.1 3e-20 72.1 4.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like YPEB PF14620.1 AEO65112.1 - 0.029 13.3 0.1 0.031 13.2 0.1 1.0 1 0 0 1 1 1 0 YpeB sporulation BBS2_C PF14782.1 AEO65112.1 - 0.081 11.4 0.0 0.09 11.3 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal ApbA PF02558.11 AEO65114.1 - 1.9e-24 85.8 0.0 2.8e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 AEO65114.1 - 3.5e-21 75.4 0.0 5.6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DUF3475 PF11961.3 AEO65114.1 - 0.11 12.3 0.3 0.22 11.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3475) MFS_1 PF07690.11 AEO65115.1 - 2.3e-31 108.8 45.4 2.3e-31 108.8 31.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 AEO65115.1 - 0.0034 17.1 3.6 0.011 15.4 0.2 2.7 2 0 0 2 2 2 1 MFS_1 like family Wbp11 PF09429.5 AEO65116.1 - 4.4e-23 81.0 14.7 4.4e-23 81.0 10.2 2.2 2 0 0 2 2 2 1 WW domain binding protein 11 DUF2294 PF10057.4 AEO65116.1 - 0.02 14.5 0.1 0.034 13.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) Lipoprotein_7 PF01540.11 AEO65116.1 - 0.023 13.7 5.6 0.032 13.2 3.9 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein DUF3450 PF11932.3 AEO65116.1 - 0.21 10.8 3.8 0.35 10.0 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Pkinase PF00069.20 AEO65117.1 - 1.6e-58 197.9 0.0 1e-57 195.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO65117.1 - 2.1e-28 99.1 0.2 3.1e-20 72.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 AEO65117.1 - 4e-07 30.4 0.2 1e-06 29.1 0.1 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 AEO65117.1 - 0.00058 18.9 0.7 0.0022 17.0 0.0 2.1 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 AEO65117.1 - 0.0061 16.3 0.2 0.082 12.6 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family CFEM PF05730.6 AEO65118.1 - 0.00085 19.0 5.5 0.0017 18.1 3.8 1.4 1 0 0 1 1 1 1 CFEM domain GATA PF00320.22 AEO65119.1 - 1.7e-16 59.2 1.9 3.4e-16 58.3 1.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 AEO65119.1 - 1.6e-11 43.5 1.6 3.1e-11 42.6 1.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) vMSA PF00695.14 AEO65119.1 - 0.14 11.2 1.0 0.4 9.8 0.7 1.7 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Aldedh PF00171.17 AEO65120.1 - 8.2e-115 383.7 0.0 9.7e-115 383.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family E1-E2_ATPase PF00122.15 AEO65121.1 - 2.9e-14 52.6 0.0 5.9e-13 48.3 0.0 3.0 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 AEO65121.1 - 6.2e-13 49.3 0.0 2e-12 47.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO65121.1 - 8.6e-13 48.0 0.0 2.6e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 AEO65121.1 - 2.2e-11 44.6 2.2 1.1e-09 39.0 1.6 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AEO65121.1 - 0.021 14.3 0.6 0.059 12.9 0.2 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Mito_fiss_reg PF05308.6 AEO65122.1 - 0.96 8.7 9.2 2.3 7.5 6.4 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator vATP-synt_E PF01991.13 AEO65123.1 - 2.3e-45 154.3 9.8 2.5e-45 154.1 6.8 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF2255 PF10012.4 AEO65123.1 - 0.034 14.1 0.7 0.034 14.1 0.5 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2255) MRP-63 PF14978.1 AEO65123.1 - 0.23 11.9 2.2 0.42 11.0 1.3 1.7 1 1 1 2 2 2 0 Mitochondrial ribosome protein 63 Gluconate_2-dh3 PF13618.1 AEO65123.1 - 2.6 8.1 6.3 4.2 7.5 2.6 2.4 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Mg_trans_NIPA PF05653.9 AEO65124.1 - 2.6e-16 59.4 4.6 4.3e-16 58.7 3.2 1.3 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 AEO65124.1 - 4.8e-06 26.6 11.0 0.00046 20.2 0.3 2.5 2 0 0 2 2 2 2 EamA-like transporter family Multi_Drug_Res PF00893.14 AEO65124.1 - 1.9 9.0 7.6 11 6.6 0.2 2.9 3 0 0 3 3 3 0 Small Multidrug Resistance protein IncA PF04156.9 AEO65124.1 - 3.9 7.0 7.4 16 5.0 0.0 3.2 3 0 0 3 3 3 0 IncA protein Tetraspannin PF00335.15 AEO65125.1 - 1.3e-08 34.4 9.7 1.7e-08 34.0 6.7 1.1 1 0 0 1 1 1 1 Tetraspanin family UPF0220 PF05255.6 AEO65125.1 - 0.23 10.7 4.8 0.19 10.9 2.1 1.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0220) GWT1 PF06423.7 AEO65125.1 - 0.36 10.9 3.4 0.31 11.1 1.2 1.8 2 1 0 2 2 2 0 GWT1 DUF1282 PF06930.7 AEO65125.1 - 0.37 10.4 12.3 0.94 9.1 8.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) DUF1772 PF08592.6 AEO65125.1 - 1 9.0 7.3 0.23 11.1 2.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF202 PF02656.10 AEO65125.1 - 9.5 6.5 9.7 75 3.6 6.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) SRF-TF PF00319.13 AEO65126.1 - 8.4e-24 82.5 0.4 1.2e-23 82.1 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3246 PF11596.3 AEO65126.1 - 0.092 12.0 0.1 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Ctr PF04145.10 AEO65127.1 - 1.5e-29 102.9 0.3 1.8e-29 102.6 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF1517 PF07466.6 AEO65127.1 - 0.088 11.7 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) zf-H2C2_2 PF13465.1 AEO65130.1 - 6e-09 35.7 6.8 0.00015 21.9 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 AEO65130.1 - 7.1e-07 29.1 10.2 0.00018 21.6 1.5 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO65130.1 - 0.00025 21.1 6.9 0.012 15.9 1.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger BolA PF01722.13 AEO65130.1 - 0.00026 20.8 0.3 0.22 11.5 0.1 2.3 2 0 0 2 2 2 2 BolA-like protein X8 PF07983.8 AEO65132.1 - 0.028 14.9 2.3 0.068 13.6 1.6 1.6 1 0 0 1 1 1 0 X8 domain Mid2 PF04478.7 AEO65133.1 - 9.4e-08 31.6 0.7 2.6e-07 30.1 0.5 1.7 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF533 PF04391.7 AEO65133.1 - 0.025 13.9 1.6 0.1 11.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF533) DUF605 PF04652.11 AEO65133.1 - 0.66 9.3 23.6 0.93 8.8 16.4 1.2 1 0 0 1 1 1 0 Vta1 like DUF572 PF04502.8 AEO65133.1 - 1.4 8.0 8.4 1.9 7.6 5.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) TFIIA PF03153.8 AEO65133.1 - 2.2 8.1 8.1 2.5 7.8 5.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2413 PF10310.4 AEO65133.1 - 2.7 6.6 10.0 3.5 6.3 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF566 PF04484.7 AEO65133.1 - 6.8 6.1 18.3 11 5.4 12.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Glyco_hydro_18 PF00704.23 AEO65134.1 - 7.7e-19 68.3 3.3 4.1e-18 65.9 2.3 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 AEO65134.1 - 4.7e-10 39.1 0.0 1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 LysM domain Myb_DNA-binding PF00249.26 AEO65135.1 - 3.5e-15 55.7 0.2 4.8e-08 32.9 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO65135.1 - 2.6e-12 46.6 0.1 8.8e-05 22.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 AEO65135.1 - 0.14 12.0 0.0 0.44 10.3 0.0 1.9 1 0 0 1 1 1 0 Rap1 Myb domain Ribosomal_S4e PF00900.15 AEO65136.1 - 3.4e-32 109.9 0.5 7.1e-32 108.9 0.3 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 AEO65136.1 - 5.9e-19 67.6 4.9 1.2e-18 66.6 3.4 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 AEO65136.1 - 2.7e-06 26.7 0.1 4.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 AEO65136.1 - 0.00031 20.3 1.3 0.00031 20.3 0.9 3.1 4 0 0 4 4 4 1 KOW motif FAD-oxidase_C PF02913.14 AEO65137.1 - 1.2e-61 208.2 0.3 2.6e-61 207.0 0.1 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 AEO65137.1 - 1.6e-35 121.5 0.0 3.2e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 AEO65137.1 - 0.047 12.1 0.0 0.075 11.4 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) RdRP PF05183.7 AEO65138.1 - 6.5e-179 596.3 0.0 9.1e-179 595.8 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 AEO65138.1 - 0.0013 18.6 0.0 0.0094 15.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO65138.1 - 0.0051 16.4 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO65138.1 - 0.09 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif 2OG-FeII_Oxy_4 PF13661.1 AEO65139.1 - 1e-05 25.0 0.1 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 AEO65139.1 - 0.00025 21.5 0.0 0.00041 20.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily E1-N PF14463.1 AEO65140.1 - 0.088 12.3 0.1 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 E1 N-terminal domain AWPM-19 PF05512.6 AEO65140.1 - 0.094 12.7 0.1 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 AWPM-19-like family Cupin_2 PF07883.6 AEO65141.1 - 0.0053 16.2 1.0 0.0082 15.6 0.7 1.4 1 1 0 1 1 1 1 Cupin domain PI-PLC-X PF00388.14 AEO65143.1 - 1.2e-57 193.4 0.0 1.6e-56 189.7 0.0 2.4 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 AEO65143.1 - 4.4e-34 116.9 0.0 6.9e-34 116.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Zn_Tnp_IS1595 PF12760.2 AEO65144.1 - 0.0017 18.1 0.6 0.0025 17.5 0.4 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF35_N PF12172.3 AEO65144.1 - 0.017 14.9 6.0 0.67 9.9 1.3 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-tcix PF14952.1 AEO65144.1 - 0.4 10.0 5.8 0.3 10.4 0.7 2.1 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Pox_A3L PF05288.6 AEO65144.1 - 0.98 9.1 2.9 3.3 7.5 0.0 2.0 1 1 1 2 2 2 0 Poxvirus A3L Protein Zn-ribbon_8 PF09723.5 AEO65144.1 - 1.1 9.3 4.4 2.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Zinc ribbon domain DUF2387 PF09526.5 AEO65144.1 - 1.2 9.1 3.6 2.2 8.2 2.5 1.5 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) CMS1 PF14617.1 AEO65145.1 - 1.1e-99 332.5 1.4 1.3e-99 332.3 1.0 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 AEO65145.1 - 6.9e-08 32.1 0.0 7.4e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Med19 PF10278.4 AEO65145.1 - 1.6 8.4 8.5 3.4 7.3 5.7 1.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 PQ-loop PF04193.9 AEO65146.1 - 1.1e-16 60.0 7.6 1.6e-13 49.9 0.2 3.2 2 1 1 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 AEO65146.1 - 0.0075 16.1 1.0 0.53 10.1 0.1 2.6 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange DUF4535 PF15054.1 AEO65146.1 - 0.046 13.1 0.2 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) ABC2_membrane_5 PF13346.1 AEO65146.1 - 0.96 8.7 7.5 4.9 6.3 2.3 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Ras PF00071.17 AEO65147.1 - 1.2e-52 177.5 0.0 1.4e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO65147.1 - 3.2e-18 66.3 0.1 6.5e-18 65.3 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AEO65147.1 - 1.5e-09 37.3 0.0 1.8e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AEO65147.1 - 4e-06 26.4 0.1 0.00011 21.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AEO65147.1 - 0.00094 19.1 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 AEO65147.1 - 0.009 16.0 1.2 0.3 11.0 0.8 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AEO65147.1 - 0.025 14.7 0.8 0.82 9.8 0.1 2.8 1 1 1 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 AEO65147.1 - 0.025 13.7 0.0 0.033 13.3 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Septin PF00735.13 AEO65147.1 - 0.078 11.9 0.0 0.17 10.9 0.0 1.5 2 0 0 2 2 2 0 Septin NB-ARC PF00931.17 AEO65147.1 - 0.12 11.2 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain EGF_2 PF07974.8 AEO65148.1 - 3.6 7.8 11.2 7.1 6.8 7.8 1.5 1 0 0 1 1 1 0 EGF-like domain PepSY_2 PF13670.1 AEO65149.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain RRM_6 PF14259.1 AEO65150.1 - 1.1e-10 41.3 0.0 2.1e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO65150.1 - 2.3e-10 39.9 0.0 5.1e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO65150.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TEX19 PF15553.1 AEO65150.1 - 0.66 9.8 9.0 0.094 12.5 3.2 1.8 2 0 0 2 2 2 0 Testis-expressed protein 19 MIP-T3 PF10243.4 AEO65150.1 - 5.3 5.3 44.4 0.36 9.2 18.6 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 DUF4604 PF15377.1 AEO65150.1 - 8.2 6.6 48.8 0.87 9.7 24.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Ras PF00071.17 AEO65151.1 - 8.2e-53 178.1 0.0 9.4e-53 177.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO65151.1 - 1.2e-17 64.5 0.0 1.6e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO65151.1 - 1.3e-05 24.5 0.0 1.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family CENP-T PF15511.1 AEO65152.1 - 1.8e-118 396.4 15.1 3.2e-118 395.5 10.4 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 AEO65152.1 - 8.8e-11 41.8 0.0 1.5e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 AEO65152.1 - 3.9e-06 26.9 0.0 8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AEO65152.1 - 2e-05 24.5 0.0 3.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SURF1 PF02104.10 AEO65153.1 - 1.3e-65 221.1 0.1 1.7e-65 220.7 0.1 1.1 1 0 0 1 1 1 1 SURF1 family UBX PF00789.15 AEO65154.1 - 1.1e-14 54.2 0.0 1.8e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 UBX domain DUF2763 PF10961.3 AEO65154.1 - 0.04 14.3 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) DUF4064 PF13273.1 AEO65154.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) UPF0560 PF10577.4 AEO65154.1 - 0.9 7.7 13.4 0.73 8.0 8.5 1.4 1 1 0 1 1 1 0 Uncharacterised protein family UPF0560 CAF-1_p150 PF11600.3 AEO65154.1 - 1.1 8.5 26.0 1.8 7.8 18.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Fmp27_WPPW PF10359.4 AEO65154.1 - 3.2 6.0 8.1 4.5 5.5 5.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Borrelia_P83 PF05262.6 AEO65154.1 - 3.4 5.8 14.4 4.6 5.3 10.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TFIIA PF03153.8 AEO65154.1 - 3.8 7.3 17.3 6.2 6.6 12.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.1 AEO65154.1 - 4.5 6.1 17.4 8.8 5.1 12.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2076 PF09849.4 AEO65155.1 - 9.9e-11 42.1 7.8 1.2e-10 41.8 5.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 AEO65155.1 - 0.00055 19.7 2.8 0.00076 19.3 1.9 1.2 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 AEO65155.1 - 0.082 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 GCK domain DUF605 PF04652.11 AEO65155.1 - 1.6 8.0 11.9 1.9 7.7 8.2 1.1 1 0 0 1 1 1 0 Vta1 like Sas10_Utp3 PF04000.10 AEO65156.1 - 4.9e-19 68.3 0.6 4.9e-19 68.3 0.4 1.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family NPV_P10 PF05531.7 AEO65156.1 - 0.28 11.4 1.6 23 5.3 0.0 3.0 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TATR PF03430.8 AEO65156.1 - 1.3 7.5 5.2 1.5 7.3 3.6 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Toxin_43 PF15604.1 AEO65156.1 - 2.7 8.0 8.3 3.3 7.7 4.2 2.1 2 0 0 2 2 2 0 Putative toxin 43 ApbA_C PF08546.6 AEO65157.1 - 2.2e-16 59.9 0.0 4.3e-16 59.0 0.0 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 AEO65157.1 - 2.7e-16 59.3 0.0 4.1e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TniQ PF06527.6 AEO65157.1 - 0.069 13.3 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 TniQ dsDNA_bind PF01984.15 AEO65158.1 - 1.7e-26 92.2 6.4 2e-26 92.0 4.4 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 AEO65158.1 - 0.0021 18.3 0.3 0.0023 18.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4615) Coq4 PF05019.8 AEO65159.1 - 5.4e-80 267.4 0.0 6.2e-80 267.2 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SET PF00856.23 AEO65160.1 - 3.2e-16 60.0 0.0 5.1e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 SET domain RRM_6 PF14259.1 AEO65161.1 - 2.5e-06 27.3 0.0 4.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO65161.1 - 0.0012 18.3 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO65161.1 - 0.05 13.4 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 AEO65162.1 - 4.2e-23 80.3 14.5 8.3e-09 34.9 1.2 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_3 PF13570.1 AEO65162.1 - 0.002 18.3 2.7 3.3 8.1 0.1 3.7 3 0 0 3 3 3 2 PQQ-like domain PD40 PF07676.7 AEO65162.1 - 0.048 13.3 0.9 0.25 11.0 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Pkinase PF00069.20 AEO65163.1 - 4.6e-40 137.3 0.0 5.7e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO65163.1 - 6.1e-22 77.9 0.0 8e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO65163.1 - 0.0013 18.5 0.7 0.16 11.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family FHA PF00498.21 AEO65163.1 - 0.024 14.7 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 FHA domain DUF1616 PF07760.6 AEO65163.1 - 0.027 13.5 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Pox_ser-thr_kin PF05445.6 AEO65163.1 - 0.14 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MmgE_PrpD PF03972.9 AEO65164.1 - 6.3e-150 499.2 0.0 7.2e-150 499.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family PRP38 PF03371.10 AEO65167.1 - 7.1e-62 208.0 0.0 8.6e-62 207.7 0.0 1.1 1 0 0 1 1 1 1 PRP38 family DUF1509 PF07420.6 AEO65167.1 - 0.0055 16.0 11.9 0.0077 15.5 8.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1509) Corona_nucleoca PF00937.13 AEO65167.1 - 0.1 11.5 15.0 0.15 11.0 10.4 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Transformer PF06495.6 AEO65167.1 - 3.2 7.6 19.6 0.32 10.8 10.1 1.8 2 0 0 2 2 2 0 Fruit fly transformer protein Amidase PF01425.16 AEO65168.1 - 1.8e-91 307.2 11.2 4.3e-88 296.0 7.8 3.0 1 1 0 1 1 1 1 Amidase DUF4336 PF14234.1 AEO65169.1 - 6.5e-13 48.5 0.0 4.2e-08 32.7 0.0 2.5 2 1 0 3 3 3 2 Domain of unknown function (DUF4336) ApoO PF09769.4 AEO65170.1 - 2.6 7.7 6.6 2.6 7.7 0.2 3.1 3 0 0 3 3 3 0 Apolipoprotein O Syntaxin-6_N PF09177.6 AEO65170.1 - 6.2 7.3 29.7 4 7.8 0.4 5.8 5 0 0 5 5 5 0 Syntaxin 6, N-terminal Nse4_C PF08743.5 AEO65171.1 - 1.6e-36 124.2 0.0 3e-36 123.2 0.0 1.5 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 AEO65171.1 - 2.4e-18 65.6 0.0 7.2e-18 64.1 0.0 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE UPF0302 PF08864.5 AEO65171.1 - 0.081 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 UPF0302 domain CAP59_mtransfer PF11735.3 AEO65172.1 - 1.7e-56 191.1 0.0 2.2e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 PI3Ka PF00613.15 AEO65173.1 - 2.7e-58 196.1 0.3 5.1e-58 195.3 0.2 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 AEO65173.1 - 8.5e-44 149.7 0.1 1.3e-42 145.8 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 AEO65173.1 - 1.4e-34 118.9 0.0 2.2e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.1 AEO65173.1 - 0.0015 18.1 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins ADH_zinc_N PF00107.21 AEO65174.1 - 5.6e-12 45.3 0.0 9.9e-12 44.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO65174.1 - 0.0048 17.7 0.0 0.013 16.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 AEO65174.1 - 0.02 14.7 0.3 0.044 13.6 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase ACC_epsilon PF13822.1 AEO65174.1 - 0.033 14.5 0.3 0.033 14.5 0.2 2.1 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit UQ_con PF00179.21 AEO65176.1 - 8.5e-47 158.1 0.0 9.8e-47 157.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO65176.1 - 7.5e-05 22.5 0.0 9.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 AEO65176.1 - 0.0085 15.7 0.1 0.015 14.9 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 AEO65176.1 - 0.05 13.4 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.27 AEO65177.1 - 7.7e-10 38.2 11.8 3.3e-07 29.9 0.8 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat RWD PF05773.17 AEO65177.1 - 0.00096 19.0 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 AEO65177.1 - 0.073 12.9 6.1 0.2 11.5 4.2 1.7 1 0 0 1 1 1 0 Ring finger domain Rav1p_C PF12234.3 AEO65177.1 - 0.69 8.0 0.1 1 7.4 0.1 1.2 1 0 0 1 1 1 0 RAVE protein 1 C terminal DLH PF01738.13 AEO65178.1 - 1.5e-16 60.3 0.0 1.7e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AEO65178.1 - 0.00034 20.3 0.0 0.00047 19.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family NUDIX PF00293.23 AEO65179.1 - 1.8e-14 53.5 0.3 9e-14 51.2 0.2 1.8 1 1 0 1 1 1 1 NUDIX domain zf-C4H2 PF10146.4 AEO65179.1 - 0.05 13.6 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Zinc finger-containing protein Acyl-CoA_dh_1 PF00441.19 AEO65180.1 - 9.1e-43 145.9 3.0 1.7e-42 145.0 2.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 AEO65180.1 - 2.4e-29 102.2 0.2 5.3e-29 101.0 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 AEO65180.1 - 2.1e-19 68.7 0.1 4.3e-19 67.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 AEO65180.1 - 5.5e-15 55.7 1.5 5.5e-15 55.7 1.0 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 AEO65180.1 - 7.9e-05 22.1 0.6 0.00033 20.1 0.4 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.17 AEO65181.1 - 3e-140 467.8 0.1 3.9e-140 467.4 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 AEO65181.1 - 0.0042 16.3 0.1 0.39 9.8 0.0 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) adh_short_C2 PF13561.1 AEO65182.1 - 3.3e-22 79.4 0.3 1.5e-15 57.6 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AEO65182.1 - 4.3e-14 52.7 3.1 2.9e-13 50.0 0.2 2.1 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO65182.1 - 3.2e-08 33.4 0.3 5.7e-08 32.6 0.2 1.4 1 0 0 1 1 1 1 KR domain PHD PF00628.24 AEO65186.1 - 1.8e-09 37.1 2.1 1.8e-09 37.1 1.4 2.1 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.1 AEO65186.1 - 0.043 13.1 2.9 0.076 12.3 2.0 1.4 1 0 0 1 1 1 0 PHD-finger MMR_HSR1 PF01926.18 AEO65187.1 - 1.1e-10 41.4 0.0 2.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AEO65187.1 - 0.00025 20.9 0.2 0.026 14.3 0.0 2.4 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 AEO65187.1 - 0.0039 16.4 0.5 0.025 13.7 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 AEO65187.1 - 0.0096 15.9 0.7 0.025 14.5 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 AEO65187.1 - 0.0097 15.4 0.6 0.0097 15.4 0.4 1.9 2 0 0 2 2 2 1 AAA domain Arf PF00025.16 AEO65187.1 - 0.041 13.1 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family FeoB_N PF02421.13 AEO65187.1 - 0.044 13.0 0.1 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_17 PF13207.1 AEO65187.1 - 0.064 14.0 0.4 0.25 12.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 AEO65187.1 - 0.082 12.4 0.0 0.23 10.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 AEO65187.1 - 0.12 12.6 0.1 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Abhydro_lipase PF04083.11 AEO65188.1 - 1.8e-22 78.4 0.1 4e-22 77.3 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 AEO65188.1 - 4.6e-20 72.1 0.2 7.2e-20 71.5 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AEO65188.1 - 3.9e-08 33.4 0.1 6.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO65188.1 - 2e-05 24.4 0.0 0.00014 21.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 AEO65188.1 - 0.00045 19.7 0.0 0.8 9.1 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 AEO65188.1 - 0.089 12.2 0.1 14 5.0 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pet191_N PF10203.4 AEO65189.1 - 1.4e-27 95.5 3.8 1.8e-27 95.1 2.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 AEO65189.1 - 0.94 9.2 4.2 6 6.7 0.4 2.6 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Metallophos_2 PF12850.2 AEO65190.1 - 1.9e-08 34.2 1.3 3.6e-08 33.4 0.9 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AEO65190.1 - 2.8e-05 23.6 0.1 2.8e-05 23.6 0.1 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Ribosomal_60s PF00428.14 AEO65190.1 - 0.017 15.4 7.5 0.017 15.4 5.2 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Transaldolase PF00923.14 AEO65191.1 - 6.9e-95 317.4 1.0 7.9e-95 317.2 0.7 1.0 1 0 0 1 1 1 1 Transaldolase SNase PF00565.12 AEO65192.1 - 7.4e-73 241.7 2.2 2.9e-21 75.7 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 AEO65192.1 - 2e-24 85.7 0.0 9e-24 83.6 0.0 2.1 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 AEO65192.1 - 1.2e-08 34.4 0.0 2.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Sod_Cu PF00080.15 AEO65193.1 - 3e-46 157.1 4.7 3.5e-46 156.8 3.2 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CNH PF00780.17 AEO65194.1 - 4.2e-68 229.7 0.0 6.3e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 AEO65194.1 - 3.6e-30 105.1 0.0 5.4e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 AEO65194.1 - 5.8e-09 35.9 0.3 1.3e-07 31.5 0.0 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 AEO65194.1 - 0.00011 22.3 0.0 0.00087 19.4 0.0 2.5 2 1 0 2 2 2 1 PH domain GPI2 PF06432.6 AEO65196.1 - 2e-127 424.3 0.0 3.5e-127 423.5 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF1049 PF06305.6 AEO65196.1 - 3.2 7.2 5.1 7.5 6.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF912 PF06024.7 AEO65197.1 - 0.038 14.0 1.0 0.15 12.1 0.7 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Annexin PF00191.15 AEO65199.1 - 7.4e-21 73.8 0.3 9.8e-06 25.3 0.0 4.7 4 1 0 4 4 4 4 Annexin Zn_clus PF00172.13 AEO65200.1 - 1.4e-08 34.5 11.9 2.3e-08 33.8 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.4 AEO65200.1 - 3.4 6.2 6.9 3.8 6.0 4.2 1.4 1 1 0 1 1 1 0 RAM signalling pathway protein CFEM PF05730.6 AEO65201.1 - 0.00013 21.7 2.8 0.00013 21.7 2.0 3.1 2 0 0 2 2 2 1 CFEM domain Ank_5 PF13857.1 AEO65202.1 - 1.6e-05 24.9 0.5 3.5e-05 23.8 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 AEO65202.1 - 0.0056 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 AEO65202.1 - 0.01 15.5 0.6 0.025 14.3 0.4 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.1 AEO65202.1 - 0.082 13.1 0.1 0.42 10.9 0.1 2.2 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.1 AEO65202.1 - 0.097 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Acetyltransf_3 PF13302.1 AEO65203.1 - 0.053 13.6 0.1 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NDUF_B7 PF05676.8 AEO65203.1 - 2.6 7.5 4.8 2.7 7.4 0.5 2.3 1 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pirin PF02678.11 AEO65205.1 - 2.5e-24 85.2 0.6 9e-23 80.1 0.4 2.3 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 AEO65205.1 - 4.6e-05 22.8 3.9 0.00034 20.0 0.5 3.2 2 1 0 2 2 2 1 Cupin domain AMP-binding PF00501.23 AEO65206.1 - 1.3e-83 280.7 0.0 1.7e-83 280.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO65206.1 - 3.1e-17 63.2 0.6 3.1e-17 63.2 0.4 2.9 3 1 0 3 3 3 1 AMP-binding enzyme C-terminal domain 2OG-FeII_Oxy_2 PF13532.1 AEO65207.1 - 3.2e-21 76.0 0.0 6.5e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ATP12 PF07542.6 AEO65208.1 - 9.8e-29 99.7 0.5 1.7e-28 98.9 0.0 1.7 2 0 0 2 2 2 1 ATP12 chaperone protein FAD_binding_4 PF01565.18 AEO65212.1 - 1.5e-21 76.2 1.0 1.5e-21 76.2 0.7 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 AEO65212.1 - 1.3e-10 41.0 0.0 2.5e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF2786 PF10979.3 AEO65212.1 - 0.039 13.6 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Metal_resist PF13801.1 AEO65212.1 - 0.96 9.4 5.3 0.24 11.4 0.3 2.4 2 0 0 2 2 2 0 Heavy-metal resistance Peptidase_S8 PF00082.17 AEO65214.1 - 2.3e-52 177.9 9.9 3.5e-52 177.3 6.8 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 AEO65214.1 - 1e-22 80.5 0.4 2.5e-22 79.2 0.3 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beach PF02138.13 AEO65215.1 - 2.7e-109 364.8 0.0 4.6e-109 364.0 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 AEO65215.1 - 8.2e-12 44.9 0.2 5.7e-11 42.2 0.0 2.4 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 AEO65215.1 - 7.4e-10 39.2 0.0 2.4e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 AEO65215.1 - 1.2e-05 24.9 3.5 0.076 12.9 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat DDOST_48kD PF03345.9 AEO65217.1 - 1.5e-158 527.7 0.0 1.9e-158 527.4 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Isy1 PF06246.7 AEO65218.1 - 7.7e-85 284.3 0.3 1.4e-84 283.5 0.2 1.4 1 1 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 AEO65218.1 - 0.065 13.0 0.1 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 YolD-like protein Metallophos PF00149.23 AEO65219.1 - 2.8e-07 30.1 5.5 6.9e-07 28.8 3.8 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SR-25 PF10500.4 AEO65222.1 - 9.6e-05 21.9 3.8 9.6e-05 21.9 2.6 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein ATP-synt_C PF00137.16 AEO65223.1 - 1.4e-25 88.9 29.0 6e-15 54.8 4.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Polysacc_synt_3 PF13440.1 AEO65223.1 - 0.0071 15.8 0.7 0.0071 15.8 0.5 2.1 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein CNH PF00780.17 AEO65224.1 - 1.8e-80 270.2 0.0 5.5e-80 268.7 0.0 1.7 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 AEO65224.1 - 7.2e-45 152.2 0.0 1.5e-44 151.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 AEO65224.1 - 5.7e-37 127.3 0.0 3e-36 124.9 0.0 2.1 2 0 0 2 2 2 1 RhoGEF domain DEP PF00610.16 AEO65224.1 - 7.8e-15 54.3 0.1 1.5e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.24 AEO65224.1 - 0.013 15.7 0.0 0.13 12.4 0.0 2.6 2 1 0 2 2 2 0 PH domain SH3_1 PF00018.23 AEO65225.1 - 1.3e-13 50.0 0.1 2.1e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AEO65225.1 - 6.1e-11 41.7 0.1 9.3e-11 41.1 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AEO65225.1 - 8.7e-09 34.7 0.0 1.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Pex14_N PF04695.8 AEO65225.1 - 0.046 13.7 4.6 0.085 12.9 3.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2360 PF10152.4 AEO65225.1 - 2.9 8.1 12.1 0.25 11.6 5.3 1.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 AEO65225.1 - 8 5.7 15.3 13 5.1 10.6 1.2 1 0 0 1 1 1 0 Vta1 like IBR PF01485.16 AEO65226.1 - 1.8e-12 46.8 31.1 8.4e-07 28.7 3.1 3.7 3 0 0 3 3 3 2 IBR domain POP1 PF06978.6 AEO65227.1 - 1.1e-65 220.8 17.8 2.1e-65 219.9 12.3 1.5 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 AEO65227.1 - 1.3e-29 101.8 0.0 4.2e-29 100.2 0.0 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain NT-C2 PF10358.4 AEO65228.1 - 5.5e-16 58.3 0.0 2.7e-15 56.1 0.0 1.9 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins MRI PF15325.1 AEO65228.1 - 0.5 11.3 2.2 2.6 9.0 0.2 2.4 2 0 0 2 2 2 0 Modulator of retrovirus infection CENP-T PF15511.1 AEO65229.1 - 0.0046 16.2 9.9 0.0056 15.9 6.9 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T zf-C3HC4_2 PF13923.1 AEO65229.1 - 0.011 15.7 0.5 0.011 15.7 0.3 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO65229.1 - 0.072 12.7 4.9 0.68 9.6 0.2 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 AEO65229.1 - 0.35 10.4 5.7 0.16 11.5 0.6 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.20 AEO65229.1 - 0.52 10.0 0.1 0.52 10.0 0.0 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO65229.1 - 5 7.0 8.4 0.82 9.5 0.4 2.5 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 AEO65229.1 - 8.8 6.1 8.3 2.4 7.9 0.2 2.6 3 0 0 3 3 3 0 zinc-RING finger domain HSP70 PF00012.15 AEO65230.1 - 5.7e-77 259.0 1.1 5.7e-77 259.0 0.8 1.8 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 AEO65230.1 - 1.9e-05 23.4 0.3 3.5e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 MreB/Mbl protein Nucleoplasmin PF03066.10 AEO65230.1 - 0.12 11.8 6.4 0.24 10.9 4.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin Gar1 PF04410.9 AEO65230.1 - 0.26 10.7 3.1 0.54 9.6 2.1 1.5 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region Sigma70_ner PF04546.8 AEO65230.1 - 0.71 9.4 9.1 0.83 9.2 5.1 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Daxx PF03344.10 AEO65230.1 - 0.84 8.0 7.9 1.3 7.4 5.5 1.2 1 0 0 1 1 1 0 Daxx Family DUF2890 PF11081.3 AEO65230.1 - 1.3 9.0 8.0 2.9 7.9 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 AEO65230.1 - 5.6 4.7 9.8 3.4 5.4 5.1 1.6 2 0 0 2 2 2 0 Nop14-like family BSP_II PF05432.6 AEO65230.1 - 6.8 5.8 14.7 0.14 11.4 4.8 2.1 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) zf-C2H2_4 PF13894.1 AEO65232.1 - 4.7e-05 23.4 17.2 0.014 15.7 0.6 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO65232.1 - 0.00072 19.7 20.8 0.058 13.7 0.9 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_Tnp_IS1595 PF12760.2 AEO65232.1 - 0.37 10.6 3.8 0.73 9.6 2.6 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Gly-zipper_Omp PF13488.1 AEO65232.1 - 0.88 9.2 4.2 1.9 8.2 2.9 1.4 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 AEO65232.1 - 1 8.9 4.5 2.1 7.9 3.1 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Fasciclin PF02469.17 AEO65233.1 - 9.9e-41 138.7 0.0 1.7e-25 89.4 0.0 3.5 2 1 0 2 2 2 2 Fasciclin domain Rad51 PF08423.6 AEO65234.1 - 0.05 12.4 0.0 0.78 8.5 0.0 2.4 2 0 0 2 2 2 0 Rad51 Pal1 PF08316.6 AEO65235.1 - 6.2e-46 156.3 0.4 6.2e-46 156.3 0.2 2.0 2 0 0 2 2 2 1 Pal1 cell morphology protein Pkinase PF00069.20 AEO65236.1 - 1.2e-38 132.7 0.0 1.8e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO65236.1 - 8.5e-14 51.2 0.0 1.3e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO65236.1 - 1.5e-05 24.8 0.3 0.0014 18.3 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Exo_endo_phos PF03372.18 AEO65237.1 - 8.5e-13 48.8 2.6 9.6e-08 32.2 1.1 2.2 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 AEO65238.1 - 3.1e-63 213.3 0.0 3.6e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO65238.1 - 1.8e-27 96.0 0.0 2.3e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO65238.1 - 1.7e-06 27.2 0.0 2.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO65238.1 - 0.00013 21.7 0.6 0.032 13.9 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AEO65238.1 - 0.0076 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 DUF2346 PF09803.4 AEO65238.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) RabGAP-TBC PF00566.13 AEO65240.1 - 2e-45 154.8 0.0 2.9e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 AEO65240.1 - 1.4e-05 24.5 1.1 0.0035 17.1 0.2 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 AEO65240.1 - 0.00043 20.3 1.9 0.0068 16.5 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 AEO65240.1 - 0.00055 19.0 0.1 0.033 13.4 0.2 3.1 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 AEO65240.1 - 0.01 15.1 0.5 0.04 13.2 0.3 2.1 1 0 0 1 1 1 0 EF hand GRAM PF02893.15 AEO65240.1 - 0.11 11.9 0.0 0.28 10.7 0.0 1.7 1 1 0 1 1 1 0 GRAM domain HET PF06985.6 AEO65242.1 - 5.8e-20 71.8 0.0 1e-19 71.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UPF0139 PF03669.8 AEO65244.1 - 8.6e-05 22.0 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) PQ-loop PF04193.9 AEO65246.1 - 4.6e-22 77.3 8.1 1.3e-20 72.6 0.1 2.8 3 0 0 3 3 3 2 PQ loop repeat Zip PF02535.17 AEO65246.1 - 0.00069 18.7 5.6 0.0012 17.9 3.9 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter S1-P1_nuclease PF02265.11 AEO65247.1 - 1.5e-71 240.9 0.0 1.7e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Pkinase PF00069.20 AEO65252.1 - 0.0015 17.7 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 AEO65252.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C3HC4 PF00097.20 AEO65253.1 - 3.7e-05 23.2 5.5 3.7e-05 23.2 3.8 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO65253.1 - 0.00014 21.8 7.1 0.00014 21.8 4.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO65253.1 - 0.00015 21.5 11.2 0.00033 20.4 7.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AEO65253.1 - 0.00081 19.0 7.5 0.0017 17.9 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO65253.1 - 0.0052 16.8 6.9 0.019 15.0 4.8 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-dskA_traR PF01258.12 AEO65253.1 - 0.045 13.4 2.4 2.5 7.9 0.1 3.3 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger eIF-5a PF01287.15 AEO65254.1 - 2.8e-06 27.1 0.1 6.6e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RCR PF12273.3 AEO65254.1 - 0.011 16.3 0.8 0.011 16.3 0.6 2.6 1 1 1 2 2 2 0 Chitin synthesis regulation, resistance to Congo red FbpA PF05833.6 AEO65255.1 - 3.2e-38 131.4 10.8 3.2e-38 131.4 7.5 2.2 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 AEO65255.1 - 1.5e-34 117.9 0.1 5.3e-34 116.2 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 AEO65255.1 - 1.1e-24 86.1 0.0 2.3e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Pol_alpha_B_N PF08418.5 AEO65255.1 - 0.95 8.9 17.7 4 6.8 12.3 2.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal PCI PF01399.22 AEO65256.1 - 1e-20 73.9 0.0 3.4e-20 72.2 0.0 1.9 1 0 0 1 1 1 1 PCI domain Asp_Glu_race_2 PF14669.1 AEO65256.1 - 3.3e-05 23.3 1.9 0.01 15.1 0.1 2.4 2 0 0 2 2 2 2 Putative aspartate racemase Cas_DxTHG PF09455.5 AEO65256.1 - 0.034 13.2 2.9 0.069 12.2 1.9 1.6 2 0 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family Neur_chan_memb PF02932.11 AEO65256.1 - 0.095 12.5 0.6 6.7 6.5 0.1 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Methyltransf_23 PF13489.1 AEO65257.1 - 1.3e-21 77.0 0.0 1.9e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO65257.1 - 4.8e-11 42.9 0.0 8.9e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO65257.1 - 9.9e-10 38.1 0.0 2.2e-08 33.8 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO65257.1 - 1.3e-09 38.6 0.0 1.2e-08 35.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO65257.1 - 3.6e-09 36.9 0.0 2.4e-08 34.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO65257.1 - 1.1e-05 25.6 0.0 2.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AEO65257.1 - 0.0045 16.0 0.0 0.014 14.4 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 AEO65257.1 - 0.009 16.0 0.0 0.067 13.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 AEO65257.1 - 0.018 15.0 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 AEO65257.1 - 0.038 13.0 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 AEO65259.1 - 2e-34 118.8 0.0 3.2e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 AEO65259.1 - 2.3e-05 24.9 0.0 5.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Spore_YhcN_YlaJ PF09580.5 AEO65259.1 - 0.08 13.0 0.5 0.18 11.9 0.3 1.5 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Tmemb_185A PF10269.4 AEO65260.1 - 0.0068 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein DUF1049 PF06305.6 AEO65260.1 - 4 6.9 5.5 1.2 8.6 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Pkinase PF00069.20 AEO65261.1 - 3.1e-33 115.0 0.0 4.4e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO65261.1 - 8.1e-17 61.1 0.0 1.2e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO65261.1 - 0.0013 17.7 0.0 0.94 8.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 AEO65261.1 - 0.018 14.1 0.0 0.055 12.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO65261.1 - 0.044 13.5 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 AEO65261.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Polyketide_cyc2 PF10604.4 AEO65263.1 - 0.0057 16.8 3.9 0.052 13.7 0.1 2.5 2 1 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport Dabb PF07876.7 AEO65264.1 - 4.7e-11 42.9 0.0 5.5e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain HATPase_c PF02518.21 AEO65266.1 - 1.6e-23 82.5 0.0 3.5e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 AEO65266.1 - 4.6e-21 75.1 0.0 1.5e-07 31.7 0.0 3.9 4 0 0 4 4 4 3 PAS domain PAS_8 PF13188.1 AEO65266.1 - 3e-13 49.0 0.0 1.8e-05 24.4 0.0 4.4 4 0 0 4 4 4 3 PAS domain Response_reg PF00072.19 AEO65266.1 - 1.8e-12 47.2 0.3 6.4e-12 45.4 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.5 AEO65266.1 - 1.5e-08 34.6 0.2 1 9.4 0.0 5.2 5 0 0 5 5 5 3 PAS fold HisKA PF00512.20 AEO65266.1 - 1.8e-08 34.2 0.2 1.8e-07 31.0 0.0 2.9 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 AEO65266.1 - 1.1e-07 31.8 0.0 3e-05 24.0 0.0 3.4 2 1 0 2 2 2 1 PAS fold PAS PF00989.19 AEO65266.1 - 4.2e-07 29.7 0.0 0.0039 16.9 0.0 3.6 4 1 0 4 4 4 2 PAS fold zf-CCHC_4 PF14392.1 AEO65267.1 - 0.34 10.5 5.8 5.1 6.8 0.3 3.0 3 0 0 3 3 3 0 Zinc knuckle GILT PF03227.11 AEO65267.1 - 0.35 10.7 2.7 5.1 6.9 0.1 2.4 2 1 0 2 2 2 0 Gamma interferon inducible lysosomal thiol reductase (GILT) C1_1 PF00130.17 AEO65267.1 - 0.64 9.7 7.5 3.5 7.4 0.2 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.1 AEO65267.1 - 1.2 8.4 4.6 12 5.2 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain TNFR_c6 PF00020.13 AEO65267.1 - 1.2 9.3 12.6 0.71 9.9 0.9 2.6 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region zf-H2C2_5 PF13909.1 AEO65267.1 - 1.3 9.3 6.7 11 6.4 0.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Fer4_17 PF13534.1 AEO65267.1 - 2 8.7 10.9 9.4 6.6 7.5 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.2 AEO65267.1 - 4.4 7.8 12.4 1.6 9.2 0.9 2.5 3 0 0 3 3 3 0 4Fe-4S binding domain PhnA_Zn_Ribbon PF08274.7 AEO65267.1 - 8 6.3 9.8 1.9 8.3 0.4 2.7 3 0 0 3 3 3 0 PhnA Zinc-Ribbon PT PF04886.7 AEO65268.1 - 0.0038 16.5 5.5 0.0038 16.5 3.8 3.9 4 1 0 4 4 4 1 PT repeat ENOD93 PF03386.9 AEO65268.1 - 0.16 11.7 4.4 3.4 7.4 0.3 3.1 3 0 0 3 3 3 0 Early nodulin 93 ENOD93 protein G-patch PF01585.18 AEO65271.1 - 1e-12 47.5 0.9 2.2e-12 46.5 0.6 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.17 AEO65271.1 - 4.2e-08 32.7 0.5 0.00076 19.0 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO65271.1 - 1.5e-07 31.3 0.2 0.023 14.6 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 AEO65271.1 - 1.5e-07 30.3 2.0 3.9e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.2 AEO65271.1 - 6.1e-05 22.7 5.1 0.00015 21.5 1.8 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site RRM_5 PF13893.1 AEO65271.1 - 6.4e-05 22.7 0.0 0.37 10.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 AEO65271.1 - 0.63 9.9 5.7 0.91 9.3 2.4 2.1 2 0 0 2 2 2 0 Double zinc ribbon Mucin PF01456.12 AEO65271.1 - 1.6 8.5 15.8 0.64 9.7 7.5 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein zf-ribbon_3 PF13248.1 AEO65271.1 - 1.6 8.0 3.6 13 5.1 1.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain RED_N PF07808.8 AEO65271.1 - 1.7 7.8 7.1 0.076 12.2 0.7 1.9 2 1 0 2 2 2 0 RED-like protein N-terminal region Dicty_REP PF05086.7 AEO65271.1 - 3.3 5.3 3.7 4.7 4.8 2.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MoaE PF02391.12 AEO65272.1 - 2.7e-32 111.0 0.0 3.2e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 MoaE protein OPT PF03169.10 AEO65273.1 - 2.1e-182 607.8 53.3 2.4e-182 607.6 37.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4181 PF13789.1 AEO65273.1 - 0.33 10.8 6.0 15 5.5 0.1 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4181) E1-E2_ATPase PF00122.15 AEO65273.1 - 0.44 9.5 1.8 5.3 5.9 0.1 2.4 2 0 0 2 2 2 0 E1-E2 ATPase Hydrolase_6 PF13344.1 AEO65274.1 - 5.8e-26 90.3 0.0 9.8e-26 89.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO65274.1 - 5.6e-14 51.6 0.0 6e-13 48.3 0.0 2.7 2 1 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 AEO65274.1 - 4.8e-06 27.1 0.0 0.06 13.7 0.0 3.3 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AEO65274.1 - 0.00092 19.4 0.1 0.071 13.3 0.0 3.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF2866 PF11065.3 AEO65274.1 - 0.05 13.5 0.7 0.1 12.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2866) HemY_N PF07219.8 AEO65275.1 - 7.5 6.1 11.2 0.07 12.6 1.2 2.4 2 0 0 2 2 2 0 HemY protein N-terminus DUF3433 PF11915.3 AEO65277.1 - 2.7e-27 94.7 2.6 2.7e-27 94.7 1.8 3.9 6 0 0 6 6 6 2 Protein of unknown function (DUF3433) Choline_kinase PF01633.15 AEO65278.1 - 2.6e-60 203.6 0.2 7e-60 202.2 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 AEO65278.1 - 1.6e-22 78.7 0.0 2.6e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 AEO65278.1 - 3.4e-06 26.9 0.4 3.4e-06 26.9 0.3 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Med15 PF09606.5 AEO65278.1 - 0.77 7.8 11.0 1.5 6.9 7.6 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3682 PF12446.3 AEO65278.1 - 6.2 7.1 22.4 12 6.1 9.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) SCO1-SenC PF02630.9 AEO65280.1 - 2.3e-58 196.6 0.0 3.2e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 AEO65280.1 - 0.00027 20.5 0.0 0.00059 19.5 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 AEO65280.1 - 0.00048 20.1 0.0 0.003 17.6 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 AEO65280.1 - 0.048 13.2 0.0 1.5 8.3 0.0 2.8 2 1 0 2 2 2 0 Redoxin PHD PF00628.24 AEO65281.1 - 3.7e-12 45.7 7.6 3.7e-12 45.7 5.3 2.2 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 AEO65281.1 - 1.1 9.1 6.0 2.3 8.1 4.2 1.6 1 0 0 1 1 1 0 Ring finger domain SMP_2 PF10144.4 AEO65282.1 - 0.0064 15.6 0.2 0.0082 15.2 0.1 1.2 1 0 0 1 1 1 1 Bacterial virulence factor haemolysin DUF2365 PF10157.4 AEO65282.1 - 0.018 14.9 0.2 0.028 14.2 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) Rnk_N PF14760.1 AEO65282.1 - 0.021 14.9 1.3 0.052 13.6 0.9 1.7 1 0 0 1 1 1 0 Rnk N-terminus Ssu72 PF04722.8 AEO65282.1 - 0.067 12.4 0.3 0.092 12.0 0.2 1.1 1 0 0 1 1 1 0 Ssu72-like protein UreE_C PF05194.7 AEO65282.1 - 0.38 10.8 6.2 0.15 12.1 1.9 2.0 3 0 0 3 3 3 0 UreE urease accessory protein, C-terminal domain zf-C2H2 PF00096.21 AEO65283.1 - 2.6e-09 36.8 11.0 0.00036 20.7 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO65283.1 - 4.9e-07 29.7 9.3 8.2e-07 29.0 0.6 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO65283.1 - 2.4e-05 24.3 9.1 0.0061 16.8 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 AEO65283.1 - 0.011 15.9 3.4 0.036 14.2 1.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AEO65283.1 - 0.063 13.4 0.7 0.063 13.4 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 AEO65283.1 - 8.6 6.2 8.7 11 5.8 0.4 2.8 1 1 2 3 3 3 0 BED zinc finger Pkinase PF00069.20 AEO65285.1 - 3.4e-57 193.5 0.0 5.3e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO65285.1 - 5.6e-35 120.6 0.0 5.5e-24 84.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase NCA2 PF08637.5 AEO65285.1 - 0.0072 15.2 0.0 0.026 13.4 0.0 1.8 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Kinase-like PF14531.1 AEO65285.1 - 0.019 13.9 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APG6 PF04111.7 AEO65285.1 - 1.6 7.6 10.3 2.9 6.8 7.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 BTB PF00651.26 AEO65286.1 - 9.9e-29 99.5 0.1 7.1e-14 51.7 0.2 3.1 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.2 AEO65286.1 - 7.5e-10 39.0 0.0 2.2e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 AEO65286.1 - 1e-09 37.6 0.4 0.00015 21.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 AEO65286.1 - 1.4e-06 28.6 0.1 3.4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO65286.1 - 6.4e-06 25.9 0.0 0.0077 16.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 AEO65286.1 - 1.4e-05 25.1 0.0 4.2e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TrmB PF01978.14 AEO65287.1 - 0.17 11.6 1.9 0.61 9.8 1.3 2.1 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2101 PF09874.4 AEO65288.1 - 1.1 8.6 12.5 1.3 8.4 8.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) RVT_1 PF00078.22 AEO65289.1 - 0.0023 17.3 0.5 0.0032 16.8 0.4 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ALO PF04030.9 AEO65290.1 - 9.4e-94 313.8 0.7 1.1e-93 313.5 0.5 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 AEO65290.1 - 2.3e-30 104.9 0.4 3.3e-30 104.3 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain APH PF01636.18 AEO65291.1 - 7.4e-09 35.6 0.1 1.2e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Rad21_Rec8 PF04824.11 AEO65292.1 - 6.8e-10 37.9 0.0 2.3e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N PF04825.8 AEO65292.1 - 0.0022 17.9 0.1 0.081 12.8 0.1 2.3 1 1 1 2 2 2 2 N terminus of Rad21 / Rec8 like protein SDA1 PF05285.7 AEO65292.1 - 0.023 13.9 4.1 0.039 13.2 2.8 1.3 1 0 0 1 1 1 0 SDA1 GDI PF00996.13 AEO65293.1 - 1.6e-41 142.0 0.0 2.1e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor RNase_PH PF01138.16 AEO65294.1 - 2.4e-14 53.7 0.0 2.6e-13 50.4 0.0 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AEO65294.1 - 0.0032 17.3 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Abhydrolase_6 PF12697.2 AEO65295.1 - 1.1e-22 81.0 15.8 3.9e-22 79.2 11.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO65295.1 - 2.7e-13 49.8 0.4 1.6e-12 47.3 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO65295.1 - 9.2e-06 25.3 0.0 0.00056 19.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 AEO65295.1 - 0.00024 20.8 0.0 0.0016 18.2 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase BAAT_C PF08840.6 AEO65295.1 - 0.0094 15.6 0.0 0.78 9.4 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.15 AEO65295.1 - 0.013 15.6 0.2 0.013 15.6 0.2 2.2 2 1 0 2 2 2 0 Thioesterase domain DLH PF01738.13 AEO65295.1 - 0.027 13.7 0.9 0.47 9.7 0.0 2.7 3 1 0 3 3 3 0 Dienelactone hydrolase family Esterase PF00756.15 AEO65295.1 - 0.028 13.8 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 Putative esterase UPF0542 PF15086.1 AEO65295.1 - 0.043 13.5 0.2 9.4 6.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 L51_S25_CI-B8 PF05047.11 AEO65297.1 - 1.3e-11 44.0 0.0 1.7e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.8 AEO65298.1 - 9.9e-41 138.4 0.9 1.3e-40 138.0 0.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Fumble PF03630.9 AEO65299.1 - 7.1e-130 432.8 0.2 1.1e-128 428.8 0.1 2.4 1 1 0 1 1 1 1 Fumble SelP_N PF04592.9 AEO65299.1 - 0.049 12.9 2.0 0.1 11.9 1.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pex14_N PF04695.8 AEO65299.1 - 0.15 12.0 3.4 0.37 10.8 2.4 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RGS PF00615.14 AEO65300.1 - 0.00032 20.7 0.0 0.022 14.8 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain MARVEL PF01284.18 AEO65300.1 - 0.73 9.6 6.2 0.36 10.6 2.1 2.1 2 1 0 2 2 2 0 Membrane-associating domain RVT_1 PF00078.22 AEO65301.1 - 0.38 10.0 1.8 1.1 8.6 0.5 1.8 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) FTA2 PF13095.1 AEO65303.1 - 1.7e-09 37.6 0.0 3.3e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 PPO1_DWL PF12142.3 AEO65305.1 - 8.3e-05 22.0 1.9 0.038 13.5 0.0 3.5 3 0 0 3 3 3 2 Polyphenol oxidase middle domain Nop14 PF04147.7 AEO65305.1 - 4.2 5.1 6.5 5.6 4.7 4.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1348 PF07080.6 AEO65306.1 - 1.2e-56 190.4 7.2 1.5e-56 190.2 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 AEO65306.1 - 3.2e-08 33.8 1.0 4.6e-08 33.3 0.7 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 AEO65306.1 - 1.5e-06 28.3 0.2 2.3e-06 27.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 AEO65306.1 - 0.029 13.9 0.1 0.048 13.2 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Redoxin PF08534.5 AEO65307.1 - 2.4e-36 124.4 0.0 2.6e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 AEO65307.1 - 5.4e-09 35.7 0.0 6.9e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF295 PF03478.13 AEO65307.1 - 0.051 12.9 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF295) DUF2226 PF09987.4 AEO65307.1 - 0.069 12.2 0.0 0.085 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) Laminin_G_3 PF13385.1 AEO65307.1 - 0.072 13.3 0.1 0.86 9.8 0.1 2.0 1 1 1 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily Ribosomal_L24e PF01246.15 AEO65308.1 - 5.8e-31 106.1 0.3 5.8e-31 106.1 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e A_deamin PF02137.13 AEO65309.1 - 3.1e-59 201.0 0.0 3.9e-58 197.4 0.0 1.9 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF1426 PF07234.6 AEO65309.1 - 0.17 11.5 0.1 0.38 10.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) NAC PF01849.13 AEO65310.1 - 8.5e-22 76.4 0.7 2.6e-21 74.8 0.2 1.9 2 0 0 2 2 2 1 NAC domain CBP4 PF07960.6 AEO65311.1 - 2.1e-39 134.0 1.7 2.5e-39 133.8 1.2 1.0 1 0 0 1 1 1 1 CBP4 Succ_CoA_lig PF13607.1 AEO65311.1 - 0.0071 15.9 0.9 0.0095 15.5 0.6 1.1 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain DUF2852 PF11014.3 AEO65311.1 - 0.024 14.5 1.3 0.025 14.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) DUF1491 PF07372.7 AEO65311.1 - 0.086 12.7 2.1 0.42 10.5 1.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1491) YdfA_immunity PF12127.3 AEO65311.1 - 1.3 7.8 5.3 1.5 7.6 3.7 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial Sel1 PF08238.7 AEO65312.1 - 3.4e-45 151.4 20.0 3.7e-08 33.7 0.0 7.8 7 0 0 7 7 7 7 Sel1 repeat RRM_1 PF00076.17 AEO65313.1 - 8.8e-06 25.2 0.0 3.9e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO65313.1 - 5e-05 23.1 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO65313.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2201_N PF13203.1 AEO65314.1 - 0.28 10.3 7.4 0.33 10.0 5.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Spore_coat_CotO PF14153.1 AEO65314.1 - 2.6 7.4 9.8 3.4 7.0 6.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Peptidase_S49_N PF08496.5 AEO65314.1 - 2.8 7.6 7.6 3.2 7.5 0.6 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal NPR3 PF03666.8 AEO65314.1 - 8.8 4.7 6.1 9.9 4.5 4.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1687 PF07955.6 AEO65315.1 - 1.1e-18 67.4 0.1 4.4e-18 65.5 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.10 AEO65315.1 - 0.018 15.1 0.0 0.33 11.0 0.0 2.2 1 1 0 1 1 1 0 ArsC family DUF2868 PF11067.3 AEO65315.1 - 0.05 12.7 0.9 0.062 12.4 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Amidohydro_1 PF01979.15 AEO65316.1 - 9.9e-17 61.5 0.3 2.4e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 AEO65316.1 - 6.8e-13 49.2 6.7 1.4e-12 48.2 4.6 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 AEO65316.1 - 1.7e-09 37.3 0.1 1.2e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 AEO65316.1 - 0.0044 16.3 5.7 0.0087 15.3 0.1 2.6 2 1 0 2 2 2 1 Amidohydrolase family MR_MLE_C PF13378.1 AEO65316.1 - 0.065 13.2 0.3 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 Enolase C-terminal domain-like Glyco_hydro_35 PF01301.14 AEO65317.1 - 3.5e-82 276.2 0.0 4.6e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 AEO65317.1 - 4.8e-43 146.6 0.1 8.7e-43 145.7 0.1 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 AEO65317.1 - 6.3e-43 145.5 3.3 3.3e-21 75.6 1.1 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 AEO65317.1 - 3.2e-18 64.8 0.0 6e-18 64.0 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Arg_repressor_C PF02863.13 AEO65317.1 - 0.064 12.7 0.0 15 5.1 0.0 2.5 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain NicO PF03824.11 AEO65318.1 - 0.52 9.5 3.1 0.87 8.8 2.2 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein zf-C2H2 PF00096.21 AEO65319.1 - 1.3e-24 84.9 32.2 1.5e-05 25.0 0.6 7.6 6 1 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO65319.1 - 1.1e-23 82.2 25.5 6e-07 29.4 0.1 6.2 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2_6 PF13912.1 AEO65319.1 - 2.9e-13 49.1 16.0 0.0023 17.7 0.1 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_4 PF13894.1 AEO65319.1 - 1.5e-12 46.9 45.5 0.0024 18.0 0.9 7.8 8 0 0 8 8 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO65319.1 - 1.8e-11 43.7 13.1 0.051 13.7 0.0 5.8 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO65319.1 - 0.00013 22.0 20.7 0.32 11.2 0.2 6.0 5 1 1 6 6 6 3 Zinc-finger of C2H2 type zf-Di19 PF05605.7 AEO65319.1 - 0.00052 20.0 22.7 0.13 12.3 1.3 5.4 5 1 0 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 AEO65319.1 - 0.021 14.4 10.7 4.1 7.1 0.2 4.8 4 0 0 4 4 4 0 zinc-finger of a C2HC-type NADH-G_4Fe-4S_3 PF10588.4 AEO65319.1 - 0.034 13.3 5.6 1.3 8.3 0.1 3.7 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-C2H2_2 PF12756.2 AEO65319.1 - 0.16 12.1 19.6 0.55 10.3 0.6 5.1 3 1 3 6 6 5 0 C2H2 type zinc-finger (2 copies) zf-RING_3 PF14369.1 AEO65319.1 - 0.46 10.5 12.7 1.7 8.7 0.1 4.6 4 0 0 4 4 4 0 zinc-finger DUF2225 PF09986.4 AEO65319.1 - 9.4 5.6 5.9 22 4.3 0.3 2.9 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) DEAD PF00270.24 AEO65321.1 - 9e-46 155.4 0.0 1.3e-43 148.4 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO65321.1 - 8.1e-24 83.2 0.0 1.7e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO65321.1 - 0.002 17.9 0.0 0.0064 16.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 AEO65321.1 - 0.0021 16.9 0.0 0.0037 16.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HMG_box PF00505.14 AEO65322.1 - 3.7e-09 36.7 0.7 3.3e-06 27.2 0.1 3.6 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 AEO65322.1 - 1.4e-06 28.5 10.4 0.0012 19.1 0.1 3.4 3 0 0 3 3 3 2 HMG-box domain HMG_box_5 PF14887.1 AEO65322.1 - 0.017 14.8 0.1 0.017 14.8 0.0 2.9 3 1 0 3 3 3 0 HMG (high mobility group) box 5 DDHD PF02862.12 AEO65322.1 - 2.1 8.0 4.5 2.4 7.9 1.7 1.9 2 0 0 2 2 2 0 DDHD domain 3Beta_HSD PF01073.14 AEO65324.1 - 5.2e-68 228.7 0.0 6.2e-68 228.5 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AEO65324.1 - 7.1e-33 113.9 1.3 1.1e-32 113.4 0.2 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO65324.1 - 1.5e-17 63.3 2.2 6.2e-15 54.7 1.5 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 AEO65324.1 - 9.5e-16 57.5 0.2 1.2e-15 57.1 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 AEO65324.1 - 3.6e-13 49.9 0.1 5.1e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 AEO65324.1 - 1.7e-08 33.7 0.9 1.6e-07 30.5 0.3 2.5 2 2 1 3 3 3 1 Polysaccharide biosynthesis protein adh_short PF00106.20 AEO65324.1 - 5.9e-08 32.7 0.2 1.4e-07 31.6 0.2 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO65324.1 - 1.8e-05 24.4 1.3 5.8e-05 22.8 0.9 1.8 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 AEO65324.1 - 0.00035 19.9 0.0 0.00055 19.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 AEO65324.1 - 0.00051 20.0 0.9 0.00063 19.7 0.1 1.6 2 0 0 2 2 2 1 TrkA-N domain Saccharop_dh PF03435.13 AEO65324.1 - 0.0011 18.0 0.3 0.002 17.1 0.2 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 AEO65324.1 - 0.0034 17.2 0.1 0.019 14.8 0.1 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.11 AEO65324.1 - 0.0041 17.4 0.0 0.0088 16.4 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF2934 PF11154.3 AEO65324.1 - 0.062 12.6 0.2 0.14 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) RhoGAP PF00620.22 AEO65325.1 - 8.2e-37 126.1 0.1 1.6e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 AEO65325.1 - 1.9e-29 101.4 34.6 1.3e-11 44.3 4.0 4.9 5 0 0 5 5 5 4 LIM domain DUF2417 PF10329.4 AEO65326.1 - 8.9e-81 270.6 3.5 1.3e-80 270.1 2.4 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 AEO65326.1 - 0.00016 21.6 1.2 0.00035 20.5 0.8 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family GSu_C4xC__C2xCH PF09698.5 AEO65326.1 - 1.2 9.3 3.4 1.4 9.1 0.9 2.2 2 0 0 2 2 2 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) DUF2890 PF11081.3 AEO65328.1 - 0.078 13.0 2.0 0.14 12.2 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 AEO65328.1 - 0.15 9.9 2.3 0.18 9.6 1.6 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 AEO65328.1 - 1.2 7.0 3.4 1.6 6.6 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 AEO65328.1 - 1.9 6.7 8.6 2.7 6.2 5.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UQ_con PF00179.21 AEO65329.1 - 7.4e-16 57.8 0.1 1.3e-08 34.4 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO65329.1 - 0.025 14.3 0.0 0.058 13.1 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B AAA PF00004.24 AEO65330.1 - 6.4e-16 58.7 0.0 2.1e-15 57.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 AEO65330.1 - 3.9e-13 49.3 0.0 1.2e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 AEO65330.1 - 4.6e-11 42.5 0.0 1e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 AEO65330.1 - 6.4e-11 41.6 0.0 1.2e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 AEO65330.1 - 5.5e-07 29.7 0.1 0.00029 20.9 0.0 3.2 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AEO65330.1 - 6e-07 28.7 0.0 2.4e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AEO65330.1 - 8.1e-06 25.5 0.0 3.4e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 AEO65330.1 - 1.9e-05 24.7 0.2 0.00099 19.1 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_11 PF13086.1 AEO65330.1 - 2.3e-05 24.0 0.0 3.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 AEO65330.1 - 0.00014 21.1 0.0 0.009 15.1 0.0 2.7 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 AEO65330.1 - 0.00014 21.7 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 AEO65330.1 - 0.0025 16.8 0.0 0.0038 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.1 AEO65330.1 - 0.0027 17.2 0.0 0.15 11.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AEO65330.1 - 0.0028 18.4 0.0 0.0086 16.8 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.1 AEO65330.1 - 0.0035 16.9 0.3 0.0081 15.7 0.2 1.7 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 AEO65330.1 - 0.0049 16.3 0.1 0.042 13.3 0.0 2.2 2 1 0 2 2 2 1 FtsK/SpoIIIE family DUF2075 PF09848.4 AEO65330.1 - 0.0054 15.7 0.0 0.0098 14.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 AEO65330.1 - 0.0067 16.1 0.2 0.046 13.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 AEO65330.1 - 0.0079 15.6 0.6 0.036 13.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 AEO65330.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit TMP_2 PF06791.8 AEO65330.1 - 0.015 14.9 0.3 0.03 13.9 0.2 1.5 1 0 0 1 1 1 0 Prophage tail length tape measure protein AAA_18 PF13238.1 AEO65330.1 - 0.022 15.0 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AEO65330.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AEO65330.1 - 0.031 14.1 0.0 0.14 12.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.6 AEO65330.1 - 0.077 12.5 0.0 0.45 10.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 AEO65330.1 - 0.096 12.1 0.3 1.6 8.1 0.0 2.4 2 1 0 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 AEO65330.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 AEO65330.1 - 0.14 10.8 0.0 2.8 6.6 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain ResIII PF04851.10 AEO65330.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit Exonuc_VII_S PF02609.11 AEO65331.1 - 0.36 10.6 0.1 0.36 10.6 0.1 2.8 2 0 0 2 2 2 0 Exonuclease VII small subunit MerR-DNA-bind PF09278.6 AEO65331.1 - 5.8 7.3 15.9 3.8 7.9 0.1 4.0 4 0 0 4 4 4 0 MerR, DNA binding Sec63 PF02889.11 AEO65332.1 - 2e-196 651.4 0.2 3.3e-109 364.9 0.0 2.6 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 AEO65332.1 - 2e-53 180.3 0.0 1.2e-31 109.4 0.0 3.9 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 AEO65332.1 - 7.3e-17 61.7 0.0 2.7e-09 37.0 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AEO65332.1 - 2.3e-11 43.3 0.0 1.5e-09 37.6 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AEO65332.1 - 2.8e-07 30.7 0.0 0.004 17.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain T2SE PF00437.15 AEO65332.1 - 3.8e-05 22.7 0.0 0.11 11.3 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 AEO65332.1 - 0.00031 20.2 0.0 1.3 8.3 0.0 3.8 4 0 0 4 4 4 2 AAA-like domain AAA_19 PF13245.1 AEO65332.1 - 0.001 18.7 0.0 0.07 12.8 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 AEO65332.1 - 0.0014 17.9 0.0 0.7 9.0 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.16 AEO65332.1 - 0.0058 15.9 0.0 1.4 8.1 0.0 2.7 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF3335 PF11814.3 AEO65332.1 - 0.011 14.9 0.3 4.6 6.3 0.0 3.3 3 0 0 3 3 3 0 Peptidase_C39 like family FtsK_SpoIIIE PF01580.13 AEO65332.1 - 0.014 14.8 0.0 7.5 5.9 0.0 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family PWWP PF00855.12 AEO65333.1 - 2.6e-11 43.5 0.0 2.6e-11 43.5 0.0 2.7 3 0 0 3 3 3 1 PWWP domain ORC3_N PF07034.6 AEO65334.1 - 7.5e-32 110.5 0.1 8.4e-31 107.1 0.1 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Spore_SspJ PF09575.5 AEO65334.1 - 0.14 12.4 0.0 0.46 10.7 0.0 1.9 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) Sec66 PF09802.4 AEO65336.1 - 5.1e-82 273.8 0.1 5.9e-82 273.6 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF4456 PF14644.1 AEO65336.1 - 0.055 12.6 0.3 0.085 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) FUSC PF04632.7 AEO65336.1 - 2.8 6.2 5.2 0.55 8.5 0.8 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF3649 PF12365.3 AEO65336.1 - 7 6.2 7.3 5.6 6.5 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) NPL4 PF05021.10 AEO65337.1 - 1.3e-129 431.8 0.0 1.6e-129 431.4 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 AEO65337.1 - 4.5e-73 243.7 0.1 8.9e-73 242.7 0.1 1.5 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 AEO65337.1 - 0.00022 21.4 0.0 0.00074 19.7 0.0 1.9 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 CPSase_L_D2 PF02786.12 AEO65339.1 - 1.8e-111 370.4 0.1 1.5e-84 282.4 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 AEO65339.1 - 4.9e-42 142.5 0.1 1.2e-41 141.2 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 AEO65339.1 - 2e-40 138.4 0.1 7.2e-23 81.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 AEO65339.1 - 2e-35 121.2 0.0 4e-17 62.2 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 AEO65339.1 - 1.2e-24 86.7 0.0 2.3e-08 33.1 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AEO65339.1 - 6.3e-23 80.9 0.1 1.4e-10 40.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AEO65339.1 - 2.3e-18 66.3 0.8 1e-08 34.8 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 AEO65339.1 - 5.6e-09 35.7 0.1 9.8e-06 25.1 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 AEO65339.1 - 2.1e-07 30.9 0.2 0.023 14.5 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 AEO65339.1 - 3.4e-07 30.0 0.3 0.02 14.4 0.0 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 AEO65339.1 - 0.00018 20.7 0.1 0.074 12.2 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain DUF1746 PF08508.5 AEO65340.1 - 7.3e-39 132.3 1.2 1e-38 131.8 0.9 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RTC_insert PF05189.8 AEO65341.1 - 4.3e-32 110.1 0.4 4.6e-31 106.8 0.1 2.4 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 AEO65341.1 - 2.2e-31 108.3 0.1 3.4e-31 107.8 0.1 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase PPR_2 PF13041.1 AEO65342.1 - 1.2e-13 50.8 0.0 3.7e-08 33.1 0.0 5.5 6 0 0 6 6 6 2 PPR repeat family PPR_3 PF13812.1 AEO65342.1 - 1.1e-06 28.3 7.0 0.13 12.5 0.0 7.5 9 0 0 9 9 9 2 Pentatricopeptide repeat domain PPR PF01535.15 AEO65342.1 - 8.9e-06 25.3 1.8 0.00097 18.9 0.0 5.0 5 0 0 5 5 5 1 PPR repeat TPR_16 PF13432.1 AEO65342.1 - 0.022 15.4 0.6 18 6.1 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO65342.1 - 0.03 14.9 4.7 2.9 8.7 0.0 5.5 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO65342.1 - 0.11 12.9 1.1 45 4.8 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_1 PF12854.2 AEO65342.1 - 0.11 11.9 0.0 0.66 9.5 0.0 2.4 1 0 0 1 1 1 0 PPR repeat TPR_7 PF13176.1 AEO65342.1 - 0.37 10.6 1.9 3.7 7.5 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4187 PF13821.1 AEO65343.1 - 2.2e-19 68.7 1.0 8.8e-19 66.8 0.7 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 AEO65343.1 - 5.8e-06 26.0 7.4 0.00087 19.0 2.4 2.7 2 0 0 2 2 2 2 G-patch domain zf-C2H2 PF00096.21 AEO65345.1 - 7.6e-13 47.9 11.0 3.6e-06 26.9 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO65345.1 - 2.1e-10 40.1 9.4 7.1e-05 22.8 2.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO65345.1 - 1.5e-08 34.4 12.1 2.3e-07 30.7 3.2 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 AEO65345.1 - 1.2e-06 28.5 4.0 0.0001 22.3 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AEO65345.1 - 2.2e-06 27.6 5.4 0.0004 20.4 0.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AEO65345.1 - 0.00017 21.3 8.1 0.0054 16.6 0.2 2.7 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 AEO65345.1 - 0.62 10.1 3.5 15 5.7 0.3 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) LIM PF00412.17 AEO65345.1 - 0.76 9.8 3.4 1.6 8.8 2.4 1.5 1 0 0 1 1 1 0 LIM domain zf-C2HC_2 PF13913.1 AEO65345.1 - 1.2 8.8 7.1 3.3 7.4 1.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 AEO65345.1 - 5.7 6.7 6.4 6.5 6.6 1.4 2.3 1 1 1 2 2 2 0 BED zinc finger ATP_bind_4 PF01902.12 AEO65346.1 - 1.2e-18 67.2 0.0 2.5e-16 59.7 0.0 2.7 2 1 0 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 AEO65346.1 - 1.3e-06 28.1 0.1 0.0067 16.1 0.0 3.6 3 1 0 3 3 3 2 Endoribonuclease L-PSP COesterase PF00135.23 AEO65347.1 - 7.7e-82 275.6 0.0 9.6e-82 275.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO65347.1 - 0.00039 20.0 1.1 0.00075 19.1 0.8 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO65347.1 - 0.0051 16.5 0.2 0.0088 15.7 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DAGAT PF03982.8 AEO65349.1 - 3.7e-93 311.4 0.0 4.8e-93 311.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase zf-H2C2_2 PF13465.1 AEO65350.1 - 5.5e-15 54.8 19.1 1e-08 35.0 1.4 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 AEO65350.1 - 2.8e-10 39.8 24.1 0.0038 17.4 4.9 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO65350.1 - 2.6e-07 30.4 21.5 0.0077 16.4 4.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO65350.1 - 0.0013 18.7 10.9 0.7 10.1 2.3 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.4 AEO65350.1 - 0.022 14.5 5.0 1.4 8.8 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger domain zf-Di19 PF05605.7 AEO65350.1 - 0.078 13.1 12.2 0.36 11.0 4.8 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 AEO65350.1 - 0.098 12.5 11.8 0.83 9.6 0.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Rad50_zn_hook PF04423.9 AEO65350.1 - 0.16 11.4 2.5 1.4 8.4 0.3 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF2225 PF09986.4 AEO65350.1 - 0.36 10.2 3.1 1 8.7 0.8 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DZR PF12773.2 AEO65350.1 - 0.46 10.3 7.0 6.5 6.6 4.8 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 AEO65350.1 - 0.67 10.0 8.1 7.6 6.6 0.1 3.0 2 1 1 3 3 3 0 zinc-finger Macoilin PF09726.4 AEO65350.1 - 0.69 8.1 12.6 22 3.1 8.7 2.3 1 1 0 1 1 1 0 Transmembrane protein PyrI_C PF02748.10 AEO65350.1 - 0.86 9.0 3.0 0.55 9.7 0.6 1.8 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.5 AEO65350.1 - 1.1 9.2 10.5 6 6.9 2.7 3.0 1 1 2 3 3 3 0 Zinc ribbon domain zf-CHY PF05495.7 AEO65350.1 - 1.7 8.8 8.7 3.7 7.7 6.1 1.6 1 0 0 1 1 1 0 CHY zinc finger zinc_ribbon_5 PF13719.1 AEO65350.1 - 1.7 8.2 4.9 38 3.9 0.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 AEO65350.1 - 1.8 8.3 6.0 11 5.8 0.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GAGA PF09237.6 AEO65350.1 - 2.6 7.7 7.5 2.4 7.8 0.8 2.9 1 1 2 3 3 3 0 GAGA factor zinc_ribbon_4 PF13717.1 AEO65350.1 - 4.8 6.9 6.2 50 3.7 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 AEO65350.1 - 7.5 6.7 12.6 2.2 8.4 1.6 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 AEO65350.1 - 7.8 6.2 7.4 0.42 10.3 0.3 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type SUN PF03856.8 AEO65351.1 - 6.7e-84 281.0 13.5 9e-84 280.6 9.4 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) BNR PF02012.15 AEO65352.1 - 1.9e-16 57.1 38.4 0.093 12.6 0.2 12.3 12 0 0 12 12 12 7 BNR/Asp-box repeat Tom5 PF10642.4 AEO65352.1 - 0.17 11.5 0.1 0.41 10.3 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase DUF1484 PF07363.6 AEO65352.1 - 0.46 10.8 0.0 0.87 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) LAM_C PF12544.3 AEO65354.1 - 9.1e-05 22.5 0.0 0.00022 21.2 0.0 1.6 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.16 AEO65354.1 - 0.0061 16.7 0.1 0.056 13.6 0.0 2.5 2 1 0 2 2 2 1 Radical SAM superfamily Cypo_polyhedrin PF05865.6 AEO65354.1 - 0.098 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Cypovirus polyhedrin protein MFS_1 PF07690.11 AEO65355.1 - 2e-18 66.2 36.2 8e-10 37.9 18.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 AEO65355.1 - 0.00091 17.4 1.9 0.0018 16.4 1.3 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family CYTH PF01928.16 AEO65356.1 - 0.23 11.0 1.9 9.4 5.8 0.1 2.1 1 1 1 2 2 2 0 CYTH domain SHS2_Rpb7-N PF03876.12 AEO65357.1 - 3e-15 56.1 0.0 4.6e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 AEO65357.1 - 1.4e-07 31.4 0.0 2.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.6 AEO65358.1 - 8e-26 89.7 0.8 1.1e-25 89.2 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Apq12 PF12716.2 AEO65359.1 - 1.8e-08 33.9 9.6 2.9e-08 33.2 6.6 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis TM_helix PF05552.7 AEO65359.1 - 0.00078 19.0 2.2 0.00078 19.0 1.5 1.9 2 0 0 2 2 2 1 Conserved TM helix Caps_synth_CapC PF14102.1 AEO65359.1 - 0.044 13.9 2.0 0.061 13.4 1.4 1.2 1 0 0 1 1 1 0 Capsule biosynthesis CapC DUF2651 PF10852.3 AEO65359.1 - 0.28 11.5 6.6 0.22 11.8 2.8 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2651) ATP_bind_1 PF03029.12 AEO65360.1 - 8.7e-72 241.4 0.1 1.1e-71 241.1 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 AEO65360.1 - 3.4e-05 24.6 0.0 0.00011 23.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AEO65360.1 - 0.00015 21.6 0.0 0.00073 19.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 AEO65360.1 - 0.00031 20.8 0.0 0.00068 19.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase MobB PF03205.9 AEO65360.1 - 0.0014 18.3 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 AEO65360.1 - 0.0042 17.2 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 AEO65360.1 - 0.0058 16.1 0.0 0.018 14.5 0.0 2.0 1 1 0 1 1 1 1 AAA-like domain AAA_33 PF13671.1 AEO65360.1 - 0.0058 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 AEO65360.1 - 0.01 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_24 PF13479.1 AEO65360.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 AEO65360.1 - 0.024 14.5 0.0 0.048 13.6 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 AEO65360.1 - 0.025 14.5 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 AEO65360.1 - 0.031 14.5 0.0 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 AEO65360.1 - 0.032 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TRADD_N PF09034.5 AEO65360.1 - 0.037 14.0 0.1 0.067 13.1 0.1 1.4 1 0 0 1 1 1 0 TRADD, N-terminal domain ArsA_ATPase PF02374.10 AEO65360.1 - 0.038 13.0 0.0 0.069 12.1 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_29 PF13555.1 AEO65360.1 - 0.041 13.4 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 AEO65360.1 - 0.045 12.9 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRP54 PF00448.17 AEO65360.1 - 0.046 13.1 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_31 PF13614.1 AEO65360.1 - 0.048 13.5 0.1 0.28 11.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 AEO65360.1 - 0.051 12.9 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.12 AEO65360.1 - 0.054 12.1 0.0 0.089 11.3 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase AAA_5 PF07728.9 AEO65360.1 - 0.056 13.1 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 AEO65360.1 - 0.069 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hpr_kinase_C PF07475.7 AEO65360.1 - 0.072 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain CbiA PF01656.18 AEO65360.1 - 0.082 12.3 0.0 0.19 11.1 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.12 AEO65360.1 - 0.096 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Miro PF08477.8 AEO65360.1 - 0.11 13.0 0.0 1.6 9.2 0.0 2.7 3 0 0 3 3 3 0 Miro-like protein Collagen PF01391.13 AEO65361.1 - 1.9 8.1 4.1 16 5.1 0.1 2.8 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) S-AdoMet_synt_C PF02773.11 AEO65362.1 - 1e-76 255.2 0.3 2e-76 254.3 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 AEO65362.1 - 1.8e-46 156.9 0.0 3.1e-46 156.2 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 AEO65362.1 - 4.5e-42 142.3 0.6 1e-41 141.2 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain DUF2312 PF10073.4 AEO65362.1 - 0.11 11.8 0.1 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) THF_DHG_CYH PF00763.18 AEO65365.1 - 2.5e-20 72.6 0.1 3.6e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 AEO65365.1 - 1e-14 53.9 0.0 1.8e-08 33.6 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.17 AEO65365.1 - 0.0078 15.0 0.1 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle MMS19_N PF14500.1 AEO65366.1 - 8.4e-42 143.2 0.0 2e-41 141.9 0.0 1.6 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 AEO65366.1 - 3.8e-13 48.9 2.8 7.9e-11 41.3 0.1 4.0 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal SPC25 PF06703.6 AEO65367.1 - 9.1e-53 178.1 0.0 1.1e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF106 PF01956.11 AEO65368.1 - 9.9e-57 191.1 1.3 1.4e-56 190.6 0.9 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 RNA_pol_Rbc25 PF08292.7 AEO65369.1 - 4.5e-37 126.9 0.6 6.6e-37 126.4 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 AEO65369.1 - 7.1e-15 54.8 0.0 1e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1_2 PF13509.1 AEO65369.1 - 0.029 14.2 0.0 0.087 12.7 0.0 1.7 1 1 1 2 2 2 0 S1 domain NUFIP1 PF10453.4 AEO65370.1 - 2.7e-11 42.8 1.8 8.7e-11 41.1 1.3 1.9 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 AEO65370.1 - 0.0017 18.0 5.3 0.0041 16.7 3.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HPPK PF01288.15 AEO65370.1 - 0.12 12.0 0.2 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Ax_dynein_light PF10211.4 AEO65370.1 - 0.31 10.8 5.8 0.67 9.7 4.0 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain DUF972 PF06156.8 AEO65370.1 - 0.63 10.4 3.5 1.5 9.1 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 AEO65370.1 - 0.66 9.5 4.4 0.97 8.9 3.0 1.2 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 AEO65370.1 - 1.1 8.8 6.1 2 7.9 4.2 1.4 1 0 0 1 1 1 0 Septum formation initiator CAML PF14963.1 AEO65370.1 - 1.2 8.4 5.3 2.1 7.6 3.7 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand V-ATPase_H_N PF03224.9 AEO65371.1 - 0.065 12.3 0.0 0.081 12.0 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit H DUF4574 PF15141.1 AEO65372.1 - 0.052 13.2 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4574) SET PF00856.23 AEO65373.1 - 1.9e-10 41.2 0.0 4.7e-09 36.7 0.0 2.6 1 1 0 1 1 1 1 SET domain Ribosomal_S19 PF00203.16 AEO65374.1 - 5.1e-35 118.9 0.3 7.7e-35 118.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Glyco_hydro_53 PF07745.8 AEO65375.1 - 2.8e-121 404.3 1.0 3.1e-121 404.2 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 ADH_zinc_N PF00107.21 AEO65376.1 - 5.4e-07 29.2 0.0 1.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO65376.1 - 5.6e-05 22.8 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glutaredoxin PF00462.19 AEO65377.1 - 1.6e-12 47.2 0.0 1.6e-12 47.2 0.0 2.1 3 0 0 3 3 3 1 Glutaredoxin OTCace PF00185.19 AEO65377.1 - 0.086 12.7 0.1 2.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain dCMP_cyt_deam_2 PF08211.6 AEO65377.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region F-box PF00646.28 AEO65378.1 - 0.014 15.0 0.7 0.026 14.1 0.5 1.4 1 0 0 1 1 1 0 F-box domain Ferric_reduct PF01794.14 AEO65379.1 - 8.4e-20 71.1 13.6 8.4e-20 71.1 9.4 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 AEO65379.1 - 1.1e-07 31.6 0.0 0.00065 19.5 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 AEO65379.1 - 9.1e-06 25.6 0.0 0.0023 17.8 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 AEO65379.1 - 0.018 15.6 0.1 0.041 14.4 0.1 1.6 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Octopine_DH PF02317.12 AEO65380.1 - 3e-36 124.3 0.0 4.4e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.18 AEO65380.1 - 1.4e-11 44.3 0.0 2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 AEO65380.1 - 2.9e-06 27.6 0.0 7.7e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.1 AEO65380.1 - 1.4e-05 24.9 0.4 3.2e-05 23.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 AEO65380.1 - 0.00024 20.5 0.1 0.00067 19.1 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 AEO65380.1 - 0.0011 18.1 0.1 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 AEO65380.1 - 0.0023 16.4 0.0 0.006 15.0 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 AEO65380.1 - 0.0049 16.7 0.1 0.011 15.6 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AEO65380.1 - 0.016 14.0 0.3 0.022 13.6 0.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A MazG-like PF12643.2 AEO65380.1 - 0.044 13.7 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 MazG-like family HDPD PF02924.9 AEO65380.1 - 0.049 13.4 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage lambda head decoration protein D Lycopene_cycl PF05834.7 AEO65380.1 - 0.089 11.6 0.1 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 AEO65380.1 - 0.094 11.5 0.3 0.13 11.1 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 AEO65380.1 - 0.31 10.0 1.5 0.26 10.3 0.1 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase MFS_1 PF07690.11 AEO65381.1 - 2.7e-51 174.3 34.7 2.7e-51 174.3 24.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO65381.1 - 7.7e-18 64.3 12.9 1.6e-17 63.2 8.9 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 AEO65381.1 - 0.00013 20.2 3.0 0.00018 19.8 2.1 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.15 AEO65381.1 - 0.0053 14.8 12.2 0.037 12.0 0.4 2.5 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Nucleos_tra2_C PF07662.8 AEO65381.1 - 0.11 11.9 8.3 0.081 12.3 1.1 2.4 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter C-terminus Methyltransf_11 PF08241.7 AEO65382.1 - 6.8e-26 90.5 0.0 1.1e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO65382.1 - 1.5e-22 79.7 0.0 2.2e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO65382.1 - 8.8e-19 67.7 0.0 1.3e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO65382.1 - 2.7e-18 66.5 0.0 4.7e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO65382.1 - 7e-18 64.9 0.0 1.2e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO65382.1 - 1.5e-15 57.3 0.0 2.4e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO65382.1 - 4.6e-15 55.3 0.0 2.4e-14 53.0 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AEO65382.1 - 7.6e-14 51.7 0.1 1.3e-13 51.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO65382.1 - 1.2e-10 41.0 0.0 1.8e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 AEO65382.1 - 2e-10 40.5 0.0 3e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 AEO65382.1 - 1.4e-08 34.3 0.0 2.5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 AEO65382.1 - 6.3e-08 33.3 0.0 1.4e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 AEO65382.1 - 1.8e-06 26.6 0.0 2.4e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.15 AEO65382.1 - 6.4e-06 25.4 0.0 8.3e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 AEO65382.1 - 0.00011 20.9 0.0 0.0002 20.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.14 AEO65382.1 - 0.00012 22.1 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Nol1_Nop2_Fmu PF01189.12 AEO65382.1 - 0.0024 17.3 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_4 PF02390.12 AEO65382.1 - 0.0024 16.9 0.0 0.012 14.7 0.0 1.9 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_3 PF01596.12 AEO65382.1 - 0.0034 16.4 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_32 PF13679.1 AEO65382.1 - 0.005 16.5 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain GCD14 PF08704.5 AEO65382.1 - 0.011 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit TehB PF03848.9 AEO65382.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.8 AEO65382.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ADH_zinc_N PF00107.21 AEO65382.1 - 0.023 14.2 0.0 0.28 10.7 0.0 2.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase RrnaAD PF00398.15 AEO65382.1 - 0.031 13.3 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Fibrillarin PF01269.12 AEO65382.1 - 0.058 12.3 0.0 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin p450 PF00067.17 AEO65383.1 - 3e-70 237.0 0.0 3.9e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L21p PF00829.16 AEO65384.1 - 0.0019 18.2 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Suf PF05843.9 AEO65384.1 - 0.044 13.5 2.0 0.055 13.1 1.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 AEO65384.1 - 2.1 8.1 6.8 2.6 7.8 4.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.20 AEO65385.1 - 1.9e-44 151.7 0.0 2.8e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO65385.1 - 2.1e-19 69.6 0.0 3.8e-19 68.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO65385.1 - 0.00097 18.9 0.3 0.059 13.0 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 AEO65385.1 - 0.006 15.5 0.0 0.028 13.3 0.0 1.9 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 AEO65385.1 - 0.085 12.1 0.2 0.24 10.7 0.1 1.7 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 AEO65385.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PsaA_PsaB PF00223.14 AEO65385.1 - 0.11 10.5 0.1 0.16 10.0 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Ribosomal_60s PF00428.14 AEO65386.1 - 3.5e-28 97.8 13.4 4.1e-28 97.6 9.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein GHMP_kinases_N PF00288.21 AEO65386.1 - 0.0066 16.4 2.9 0.016 15.2 2.0 1.6 1 1 0 1 1 1 1 GHMP kinases N terminal domain DUF3824 PF12868.2 AEO65386.1 - 2.1 9.2 5.3 3 8.7 3.7 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) SPT2 PF08243.6 AEO65387.1 - 3.4e-07 30.5 26.2 3.4e-07 30.5 18.1 2.6 2 1 0 2 2 2 1 SPT2 chromatin protein Merozoite_SPAM PF07133.6 AEO65387.1 - 5.4 6.8 15.7 11 5.8 10.9 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Ribosomal_S8e PF01201.17 AEO65388.1 - 2.6e-36 124.6 9.2 5.4e-36 123.6 6.4 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e DUF2390 PF09523.5 AEO65388.1 - 6 7.0 6.6 12 6.0 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Tim17 PF02466.14 AEO65389.1 - 1.1e-29 103.0 0.2 1.6e-29 102.5 0.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CM_2 PF01817.16 AEO65389.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Chorismate mutase type II Zn_clus PF00172.13 AEO65390.1 - 1.5e-09 37.6 11.1 2.5e-09 36.8 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO65390.1 - 9.3e-09 34.5 0.3 1.5e-08 33.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HAP1_N PF04849.8 AEO65390.1 - 0.12 11.3 0.2 0.64 8.9 0.0 1.9 2 0 0 2 2 2 0 HAP1 N-terminal conserved region FAD_binding_3 PF01494.14 AEO65391.1 - 3.1e-23 82.4 0.0 4.3e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO65391.1 - 2.2e-11 43.2 0.4 3.8e-06 26.0 0.2 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO65391.1 - 3.5e-06 27.3 0.2 4.4e-05 23.8 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO65391.1 - 0.00018 21.4 0.1 0.00073 19.5 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 AEO65391.1 - 0.00083 18.8 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 AEO65391.1 - 0.0012 17.7 0.3 0.0038 16.1 0.2 1.7 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 AEO65391.1 - 0.0036 17.2 0.0 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 AEO65391.1 - 0.017 14.1 0.0 0.32 10.0 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 AEO65391.1 - 0.042 12.4 0.1 0.071 11.7 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_10 PF13460.1 AEO65391.1 - 0.046 13.7 0.1 0.094 12.7 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 AEO65391.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 AEO65392.1 - 2.4e-17 63.6 0.0 3.5e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO65392.1 - 0.00011 21.9 0.3 0.055 13.2 0.1 2.9 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 AEO65392.1 - 0.00024 21.0 0.0 0.0015 18.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO65392.1 - 0.0011 17.9 0.0 0.047 12.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) WSC PF01822.14 AEO65393.1 - 3.2e-75 248.1 62.6 9.4e-21 73.5 8.3 4.1 4 0 0 4 4 4 4 WSC domain zf-C2H2 PF00096.21 AEO65394.1 - 0.017 15.4 0.4 0.017 15.4 0.3 4.6 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO65394.1 - 0.24 11.8 13.6 0.42 11.0 0.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger MCPsignal PF00015.16 AEO65395.1 - 0.2 11.1 1.4 0.32 10.5 0.7 1.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CEP170_C PF15308.1 AEO65395.1 - 0.6 8.3 3.6 0.62 8.2 2.5 1.3 1 1 0 1 1 1 0 CEP170 C-terminus AHH PF14412.1 AEO65395.1 - 1 9.3 6.0 0.18 11.8 1.6 1.6 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH HLH PF00010.21 AEO65397.1 - 1.4e-12 47.0 0.6 1.4e-12 47.0 0.4 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain RRM_1 PF00076.17 AEO65398.1 - 1.5e-35 120.6 0.0 1.1e-17 63.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO65398.1 - 2.1e-25 88.4 0.1 1.3e-13 50.6 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO65398.1 - 5.8e-13 48.4 0.0 5.1e-08 32.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AEO65398.1 - 0.0061 16.2 0.0 1.7 8.4 0.0 2.6 2 0 0 2 2 2 2 Limkain b1 TPR_1 PF00515.23 AEO65399.1 - 1.8e-26 90.5 3.8 7.7e-09 34.7 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 AEO65399.1 - 5.3e-25 86.8 9.6 1.2e-10 40.8 0.5 4.3 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 AEO65399.1 - 2.7e-24 83.0 10.7 1.3e-07 30.9 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 AEO65399.1 - 1.1e-17 62.8 14.8 1.1e-05 25.6 0.0 7.3 5 2 4 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 AEO65399.1 - 8.1e-17 59.9 6.7 0.0013 18.7 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 AEO65399.1 - 1.9e-16 60.2 15.7 8.8e-07 29.4 1.3 4.9 5 1 1 6 6 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 AEO65399.1 - 7.9e-15 53.4 0.2 3.2e-05 23.3 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 AEO65399.1 - 1.3e-13 49.6 2.4 0.0074 16.0 0.0 6.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 AEO65399.1 - 8e-13 48.1 9.1 1.1e-07 31.6 0.2 4.5 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 AEO65399.1 - 8e-13 48.5 11.3 0.00013 22.2 3.4 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 AEO65399.1 - 1.7e-10 40.5 3.0 0.0016 18.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 AEO65399.1 - 1.3e-08 34.7 9.4 0.0089 16.1 0.1 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 AEO65399.1 - 1.4e-05 25.2 9.0 2.7 8.6 0.0 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 AEO65399.1 - 0.00013 21.1 2.7 0.13 11.3 0.5 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat NatB_MDM20 PF09797.4 AEO65399.1 - 0.038 12.7 0.1 0.073 11.7 0.0 1.4 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit CRISPR_Cse2 PF09485.5 AEO65399.1 - 0.041 13.9 0.9 0.17 11.9 0.2 2.2 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) TPR_3 PF07720.7 AEO65399.1 - 0.1 12.4 0.1 14 5.6 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1641 PF07849.6 AEO65399.1 - 0.12 11.9 0.2 0.37 10.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) TOM20_plant PF06552.7 AEO65399.1 - 0.26 10.8 2.9 9.1 5.8 0.1 4.0 4 1 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 IncA PF04156.9 AEO65399.1 - 0.26 10.8 3.1 0.54 9.8 2.1 1.5 1 0 0 1 1 1 0 IncA protein RNase_T PF00929.19 AEO65400.1 - 4.1e-23 82.4 0.0 7.6e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 AEO65400.1 - 0.017 14.5 0.0 0.042 13.3 0.0 1.6 1 1 0 1 1 1 0 3'-5' exonuclease Yippee-Mis18 PF03226.9 AEO65401.1 - 1.9e-06 27.8 0.3 3.8e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Myosin_tail_1 PF01576.14 AEO65401.1 - 0.0002 19.2 1.7 0.021 12.5 0.1 1.9 1 1 1 2 2 2 2 Myosin tail WEMBL PF05701.6 AEO65401.1 - 0.0002 19.9 5.7 0.00031 19.3 4.0 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 AEO65401.1 - 0.0002 20.6 1.8 0.3 10.2 0.1 2.0 1 1 1 2 2 2 2 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 AEO65401.1 - 0.00059 19.7 1.0 0.0013 18.6 0.2 1.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 AEO65401.1 - 0.0015 18.3 2.7 0.018 14.8 2.1 2.3 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Spc7 PF08317.6 AEO65401.1 - 0.0017 17.0 2.4 0.0077 14.9 1.7 2.1 1 1 0 1 1 1 1 Spc7 kinetochore protein FlaC_arch PF05377.6 AEO65401.1 - 0.0024 17.7 0.9 2.6 8.0 0.0 3.9 2 1 0 3 3 3 1 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 AEO65401.1 - 0.0025 17.9 0.1 0.011 15.8 0.0 2.0 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family DUF2422 PF10337.4 AEO65401.1 - 0.0043 15.8 0.5 0.0084 14.9 0.3 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF2422) Filament PF00038.16 AEO65401.1 - 0.0061 16.0 3.4 0.19 11.1 0.8 2.2 1 1 0 1 1 1 1 Intermediate filament protein DUF972 PF06156.8 AEO65401.1 - 0.0063 16.8 0.7 0.1 12.9 0.2 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF972) ADIP PF11559.3 AEO65401.1 - 0.0083 16.0 2.3 1.8 8.4 0.1 2.4 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 AEO65401.1 - 0.019 14.7 0.4 0.86 9.4 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Fez1 PF06818.10 AEO65401.1 - 0.025 14.6 3.5 0.025 14.5 1.6 1.6 1 1 1 2 2 2 0 Fez1 TMF_TATA_bd PF12325.3 AEO65401.1 - 0.027 14.2 0.2 0.08 12.6 0.0 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.7 AEO65401.1 - 0.028 14.2 0.1 0.23 11.2 0.0 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF904 PF06005.7 AEO65401.1 - 0.028 14.6 2.8 4.2 7.7 0.4 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF904) IncA PF04156.9 AEO65401.1 - 0.029 13.9 1.1 0.059 12.9 0.7 1.7 1 1 0 1 1 1 0 IncA protein Laminin_II PF06009.7 AEO65401.1 - 0.034 13.9 2.9 1.7 8.4 0.3 2.4 2 0 0 2 2 2 0 Laminin Domain II TPR_MLP1_2 PF07926.7 AEO65401.1 - 0.041 13.6 2.8 0.56 9.9 0.3 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Macoilin PF09726.4 AEO65401.1 - 0.042 12.1 0.9 0.073 11.3 0.6 1.4 1 1 0 1 1 1 0 Transmembrane protein FAM72 PF14976.1 AEO65401.1 - 0.044 13.6 0.9 0.075 12.8 0.6 1.4 1 0 0 1 1 1 0 FAM72 protein TBPIP PF07106.8 AEO65401.1 - 0.046 13.2 0.5 0.34 10.4 0.0 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 AEO65401.1 - 0.061 12.5 0.5 6.8 5.8 0.4 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding COG2 PF06148.6 AEO65401.1 - 0.062 13.1 2.8 0.65 9.8 0.3 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 EIF4E-T PF10477.4 AEO65401.1 - 0.069 11.9 0.1 0.084 11.6 0.1 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Ax_dynein_light PF10211.4 AEO65401.1 - 0.074 12.8 1.0 0.44 10.3 0.2 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain Atg14 PF10186.4 AEO65401.1 - 0.089 11.7 4.3 0.8 8.5 3.1 2.1 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CCDC144C PF14915.1 AEO65401.1 - 0.09 11.6 2.6 0.15 10.9 0.7 2.0 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region DivIVA PF05103.8 AEO65401.1 - 0.096 12.7 1.6 0.58 10.2 0.1 2.3 2 0 0 2 2 2 0 DivIVA protein Cortex-I_coil PF09304.5 AEO65401.1 - 0.1 12.6 3.4 0.17 11.9 0.6 2.4 1 1 1 2 2 2 0 Cortexillin I, coiled coil WXG100 PF06013.7 AEO65401.1 - 0.12 12.3 1.2 1.8 8.6 0.3 2.7 2 1 1 3 3 2 0 Proteins of 100 residues with WXG AAA_13 PF13166.1 AEO65401.1 - 0.13 10.6 0.3 0.34 9.3 0.2 1.5 1 1 0 1 1 1 0 AAA domain Lzipper-MIP1 PF14389.1 AEO65401.1 - 0.19 11.8 2.3 1.1 9.3 0.7 2.9 2 2 1 3 3 2 0 Leucine-zipper of ternary complex factor MIP1 BRE1 PF08647.6 AEO65401.1 - 0.21 11.5 2.8 15 5.5 0.4 2.7 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Mnd1 PF03962.10 AEO65401.1 - 0.22 11.1 1.8 2.3 7.8 1.0 2.3 1 1 0 1 1 1 0 Mnd1 family Spectrin PF00435.16 AEO65401.1 - 0.23 11.7 3.0 3.9 7.8 0.5 2.9 1 1 1 3 3 3 0 Spectrin repeat DUF641 PF04859.7 AEO65401.1 - 0.25 11.0 1.8 2.4 7.9 0.3 2.3 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF1515 PF07439.6 AEO65401.1 - 0.26 11.0 5.0 2.1 8.1 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Prefoldin_2 PF01920.15 AEO65401.1 - 0.32 10.7 4.1 12 5.6 0.0 3.2 3 1 2 5 5 4 0 Prefoldin subunit DUF4140 PF13600.1 AEO65401.1 - 2.3 8.7 7.7 1.8 9.0 0.3 3.3 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF4200 PF13863.1 AEO65401.1 - 3.3 7.6 6.6 32 4.4 0.1 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4200) SET PF00856.23 AEO65402.1 - 2.8e-10 40.7 0.0 8.6e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.13 AEO65402.1 - 4.4e-08 32.8 9.9 4.4e-08 32.8 6.9 2.6 3 1 0 3 3 3 1 MYND finger Prefoldin PF02996.12 AEO65403.1 - 1.6e-27 95.5 0.1 2.4e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 AEO65403.1 - 0.0056 16.4 0.6 2 8.2 0.0 2.2 2 0 0 2 2 2 2 Prefoldin subunit Cep57_MT_bd PF06657.8 AEO65403.1 - 0.011 15.6 0.3 0.023 14.6 0.2 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF1192 PF06698.6 AEO65403.1 - 0.26 11.1 3.6 0.22 11.3 0.4 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) AAA PF00004.24 AEO65405.1 - 5.2e-14 52.5 0.0 9e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AEO65405.1 - 4.7e-11 43.0 0.5 1.1e-09 38.5 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AEO65405.1 - 2.7e-08 34.0 0.0 5.9e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain BAH PF01426.13 AEO65405.1 - 5e-07 29.4 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_17 PF13207.1 AEO65405.1 - 0.00031 21.5 0.0 0.0016 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AEO65405.1 - 0.0012 18.5 0.4 0.0046 16.6 0.3 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 AEO65405.1 - 0.012 15.5 0.0 0.098 12.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 AEO65405.1 - 0.016 15.5 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 AEO65405.1 - 0.023 13.7 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zot PF05707.7 AEO65405.1 - 0.037 13.5 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_11 PF13086.1 AEO65405.1 - 0.038 13.5 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.1 AEO65405.1 - 0.058 12.0 0.0 0.093 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AEO65405.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 AEO65405.1 - 0.11 12.2 0.0 0.49 10.0 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase WD40 PF00400.27 AEO65406.1 - 1.2e-51 170.8 13.3 5.4e-10 38.7 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 AEO65406.1 - 0.066 11.3 4.3 15 3.5 0.1 3.9 1 1 2 4 4 4 0 Nucleoporin Nup120/160 DUF1814 PF08843.6 AEO65406.1 - 0.081 12.6 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF1814) TMF_TATA_bd PF12325.3 AEO65407.1 - 6.6e-39 132.3 10.0 6.6e-39 132.3 6.9 5.9 3 2 2 5 5 5 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 AEO65407.1 - 1e-19 70.0 9.0 1e-19 70.0 6.2 8.8 5 3 3 8 8 8 1 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 AEO65407.1 - 0.5 9.5 21.1 1.5 7.8 0.3 4.9 3 1 1 5 5 5 0 Reovirus sigma C capsid protein Fungal_trans_2 PF11951.3 AEO65407.1 - 1.6 7.2 4.3 2 6.9 1.2 2.3 1 1 1 2 2 2 0 Fungal specific transcription factor domain Ceramidase PF05875.7 AEO65408.1 - 3.8e-93 311.4 11.6 4.4e-93 311.2 8.0 1.0 1 0 0 1 1 1 1 Ceramidase Prefoldin_2 PF01920.15 AEO65409.1 - 3.9e-22 78.0 1.6 4.8e-22 77.7 1.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.3 AEO65409.1 - 0.0012 18.5 4.7 0.0062 16.2 0.0 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.7 AEO65409.1 - 0.0012 18.5 1.2 0.0017 18.1 0.9 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein CENP-Q PF13094.1 AEO65409.1 - 0.013 15.5 3.4 0.042 13.8 0.0 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF16 PF01519.11 AEO65409.1 - 0.038 14.2 3.8 0.11 12.7 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 GP41 PF00517.12 AEO65409.1 - 0.13 11.8 0.1 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 Retroviral envelope protein RtcR PF06956.6 AEO65409.1 - 0.13 11.5 0.1 0.22 10.8 0.0 1.3 1 1 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase Tropomyosin PF00261.15 AEO65409.1 - 0.18 10.8 0.1 0.18 10.8 0.1 2.0 2 0 0 2 2 2 0 Tropomyosin IncA PF04156.9 AEO65409.1 - 0.52 9.8 5.2 2.1 7.8 3.6 1.8 1 1 0 1 1 1 0 IncA protein ADIP PF11559.3 AEO65409.1 - 0.62 9.9 8.5 4.8 7.0 1.5 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding COG2 PF06148.6 AEO65409.1 - 0.7 9.7 4.2 7.3 6.4 0.6 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TBPIP PF07106.8 AEO65409.1 - 0.84 9.1 4.9 1.2 8.6 0.2 2.0 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 AEO65409.1 - 0.97 9.5 4.1 6.6 6.8 0.1 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.7 AEO65409.1 - 1.4 9.3 5.6 6.8 7.1 0.1 2.3 2 0 0 2 2 2 0 SlyX Sec2p PF06428.6 AEO65409.1 - 1.5 8.7 4.9 2.2 8.1 0.1 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p FlxA PF14282.1 AEO65409.1 - 1.5 8.7 9.2 7.9 6.4 2.8 2.2 2 0 0 2 2 2 0 FlxA-like protein Myosin_tail_1 PF01576.14 AEO65409.1 - 1.5 6.4 7.1 0.78 7.3 0.3 1.7 1 1 0 1 1 1 0 Myosin tail DivIC PF04977.10 AEO65409.1 - 4 7.0 5.6 1.8 8.1 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 AEO65409.1 - 7.6 6.4 7.7 0.69 9.7 0.5 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Dzip-like_N PF13815.1 AEO65409.1 - 8.7 6.1 7.1 11 5.8 0.3 2.1 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Mito_carr PF00153.22 AEO65411.1 - 9.5e-51 169.4 3.4 7.3e-19 67.2 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Dor1 PF04124.7 AEO65412.1 - 8.5e-67 225.0 5.7 5.9e-62 209.0 2.3 3.8 2 2 0 2 2 2 2 Dor1-like family Cellulase-like PF12876.2 AEO65412.1 - 0.062 13.7 0.0 0.37 11.2 0.0 2.3 1 0 0 1 1 1 0 Sugar-binding cellulase-like Latarcin PF10279.4 AEO65412.1 - 0.1 12.8 0.0 0.72 10.0 0.0 2.1 2 0 0 2 2 2 0 Latarcin precursor TRAM_LAG1_CLN8 PF03798.11 AEO65413.1 - 5.4e-49 166.4 8.6 7.9e-49 165.9 6.0 1.2 1 0 0 1 1 1 1 TLC domain SH3_1 PF00018.23 AEO65414.1 - 1.2e-38 130.2 5.6 7.3e-13 47.6 0.2 4.4 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.1 AEO65414.1 - 9.2e-37 124.3 7.6 1.3e-13 50.2 0.2 4.4 4 0 0 4 4 4 4 Variant SH3 domain SHD1 PF03983.7 AEO65414.1 - 5.3e-36 122.1 0.0 9.6e-36 121.2 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.12 AEO65414.1 - 2.4e-24 84.5 0.3 2.6e-08 33.1 0.0 4.3 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 AEO65414.1 - 6.6e-07 29.4 4.2 0.27 11.4 0.4 3.5 3 0 0 3 3 3 3 Bacterial SH3 domain DUF1720 PF08226.6 AEO65414.1 - 0.0057 16.6 43.3 0.0057 16.6 30.0 6.5 2 1 3 5 5 5 2 Domain of unknown function (DUF1720) A_deaminase PF00962.17 AEO65415.1 - 3.4e-110 368.0 0.1 4.7e-110 367.5 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.6 AEO65416.1 - 1.2e-100 336.3 2.4 1.4e-100 336.0 1.7 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 AEO65416.1 - 1e-05 24.8 3.6 2.2e-05 23.6 0.3 2.2 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 AEO65416.1 - 0.0005 19.7 0.5 0.0005 19.7 0.3 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 AEO65416.1 - 0.01 15.9 2.5 0.01 15.9 1.7 3.7 2 1 1 3 3 3 0 EamA-like transporter family EmrE PF13536.1 AEO65416.1 - 0.021 15.0 2.2 0.021 15.0 1.5 3.5 3 1 1 4 4 4 0 Multidrug resistance efflux transporter UPF0546 PF10639.4 AEO65416.1 - 0.15 11.8 5.6 2.8 7.7 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 Sybindin PF04099.7 AEO65417.1 - 1.9e-52 176.7 0.0 2.2e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 AEO65417.1 - 4.7e-09 36.2 0.0 9.3e-09 35.2 0.0 1.4 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region VWA_2 PF13519.1 AEO65418.1 - 5.6e-14 52.6 0.0 8.4e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 AEO65418.1 - 1.1e-07 31.6 0.1 1.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 AEO65418.1 - 2.4e-05 24.1 0.2 3.3e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 AEO65418.1 - 0.00032 20.0 1.3 0.00096 18.5 0.9 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.4 AEO65419.1 - 6.5e-23 79.8 2.8 1.1e-22 79.0 1.9 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal SUI1 PF01253.17 AEO65420.1 - 3.8e-23 81.0 1.0 6.6e-23 80.3 0.3 1.7 1 1 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 AEO65420.1 - 0.072 12.9 0.8 0.087 12.7 0.1 1.4 2 0 0 2 2 2 0 Transposon-encoded protein TnpV Methyltransf_11 PF08241.7 AEO65421.1 - 1.3e-11 44.8 0.0 3.4e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO65421.1 - 0.0056 16.4 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO65421.1 - 0.013 14.6 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 AEO65421.1 - 0.021 15.3 0.0 0.051 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 AEO65421.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 AEO65421.1 - 0.1 13.1 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain zf-C2H2_4 PF13894.1 AEO65422.1 - 0.00041 20.4 26.3 0.068 13.5 0.0 5.7 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AEO65422.1 - 0.021 14.7 0.5 0.88 9.5 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO65422.1 - 0.62 10.5 27.6 1.7 9.1 0.5 6.1 6 0 0 6 6 6 0 Zinc finger, C2H2 type Glyco_hydro_11 PF00457.12 AEO65424.1 - 2e-67 226.0 22.6 2.4e-67 225.8 15.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF4267 PF14087.1 AEO65427.1 - 5.3e-20 71.1 4.1 6e-20 70.9 2.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Metallophos PF00149.23 AEO65428.1 - 6.6e-08 32.1 3.5 1.3e-07 31.2 2.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CDC45 PF02724.9 AEO65428.1 - 0.031 12.3 3.6 0.058 11.4 2.5 1.3 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 AEO65428.1 - 0.29 11.4 14.4 0.023 14.9 4.1 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 AEO65428.1 - 0.52 9.4 8.9 0.36 9.9 4.0 1.9 2 0 0 2 2 2 0 Myc amino-terminal region DUF3381 PF11861.3 AEO65428.1 - 0.86 9.0 15.6 0.26 10.7 5.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) TIMELESS_C PF05029.8 AEO65428.1 - 0.94 8.3 15.1 0.17 10.7 6.4 2.0 2 0 0 2 2 2 0 Timeless protein C terminal region NST1 PF13945.1 AEO65428.1 - 1 9.4 13.5 1.9 8.4 0.1 2.8 3 0 0 3 3 3 0 Salt tolerance down-regulator HSP90 PF00183.13 AEO65428.1 - 1 7.6 16.9 0.03 12.7 5.7 2.1 2 0 0 2 2 2 0 Hsp90 protein NOA36 PF06524.7 AEO65428.1 - 1.5 7.9 8.8 3.1 6.9 6.1 1.4 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.1 AEO65428.1 - 2.7 7.6 4.7 6.6 6.4 3.3 1.6 1 0 0 1 1 1 0 FAM176 family Daxx PF03344.10 AEO65428.1 - 3.4 6.0 10.3 5.9 5.2 7.1 1.3 1 0 0 1 1 1 0 Daxx Family EBV-NA3 PF05009.7 AEO65428.1 - 3.5 6.7 6.2 1.1 8.4 0.9 2.3 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Sigma70_ner PF04546.8 AEO65428.1 - 7.7 6.0 14.3 1.3 8.5 6.4 2.1 3 0 0 3 3 3 0 Sigma-70, non-essential region Polysacc_deac_1 PF01522.16 AEO65429.1 - 1.7e-23 82.5 0.2 1.6e-21 76.1 0.2 2.2 1 1 0 1 1 1 1 Polysaccharide deacetylase Ank_5 PF13857.1 AEO65430.1 - 0.021 15.0 0.2 0.11 12.7 0.1 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO65430.1 - 0.06 13.8 0.0 0.45 11.1 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Cys_Met_Meta_PP PF01053.15 AEO65431.1 - 1.4e-56 191.5 0.0 3.1e-56 190.3 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Ofd1_CTDD PF10637.4 AEO65433.1 - 1.1e-103 345.9 0.0 1.6e-95 319.2 0.0 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 AEO65433.1 - 1.7e-14 54.1 0.0 4.9e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 AEO65433.1 - 0.072 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aminotran_5 PF00266.14 AEO65434.1 - 4.8e-49 167.0 0.0 6e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 AEO65434.1 - 1.3e-05 23.7 0.0 1.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Ribul_P_3_epim PF00834.14 AEO65435.1 - 7.8e-65 217.7 0.0 1.1e-63 213.9 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 AEO65435.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF4243 PF14027.1 AEO65436.1 - 5.6e-84 282.4 1.3 7.4e-84 282.0 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Rad17 PF03215.10 AEO65437.1 - 3.1e-58 197.7 0.0 4.8e-58 197.1 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 AEO65437.1 - 0.00071 19.2 0.1 0.0038 16.9 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 AEO65437.1 - 0.0023 18.0 0.0 0.0054 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO65437.1 - 0.0048 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 AEO65437.1 - 0.0081 15.7 0.0 0.024 14.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AEO65437.1 - 0.012 14.5 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 AEO65437.1 - 0.014 15.0 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 AEO65437.1 - 0.024 14.8 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AEO65437.1 - 0.041 14.6 0.0 0.095 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AEO65437.1 - 0.056 12.5 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 AEO65437.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 AEO65437.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AEO65437.1 - 0.25 11.2 0.0 0.57 10.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 AEO65437.1 - 0.26 10.9 0.0 0.5 10.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 APH PF01636.18 AEO65438.1 - 1.1e-45 156.2 0.6 2.3e-45 155.1 0.4 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 AEO65438.1 - 1.7e-05 24.1 0.0 2.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 AEO65438.1 - 0.015 14.6 0.0 2.6 7.3 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Fructosamin_kin PF03881.9 AEO65438.1 - 0.017 14.1 0.0 0.7 8.8 0.0 2.3 1 1 0 1 1 1 0 Fructosamine kinase DUF3446 PF11928.3 AEO65438.1 - 1.1 9.5 19.8 0.71 10.1 3.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) SR-25 PF10500.4 AEO65438.1 - 2.6 7.4 28.5 0.48 9.8 5.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ACC_epsilon PF13822.1 AEO65438.1 - 6.9 7.1 0.0 6.9 7.1 0.0 4.2 3 1 1 4 4 4 0 Acyl-CoA carboxylase epsilon subunit zf-RING_2 PF13639.1 AEO65439.1 - 2.6e-12 46.3 3.7 2.6e-12 46.3 2.6 1.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 AEO65439.1 - 2.3e-11 43.6 0.7 4.4e-11 42.7 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AEO65439.1 - 7.2e-07 29.1 3.9 1.3e-06 28.3 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AEO65439.1 - 7.4e-07 28.9 0.5 1.7e-06 27.7 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 AEO65439.1 - 1.3e-05 24.7 2.4 2.2e-05 24.0 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AEO65439.1 - 3e-05 23.5 2.8 5.1e-05 22.8 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO65439.1 - 0.00014 21.4 1.5 0.00024 20.7 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AEO65439.1 - 0.00034 20.2 1.6 0.001 18.7 1.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Baculo_RING PF05883.6 AEO65439.1 - 0.014 15.2 0.1 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain FANCL_C PF11793.3 AEO65439.1 - 0.015 15.2 4.0 0.23 11.4 2.8 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.3 AEO65439.1 - 0.14 11.7 2.1 0.32 10.5 1.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 AEO65439.1 - 1.7 8.5 4.8 6.2 6.7 3.5 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Cullin PF00888.17 AEO65442.1 - 1.2e-53 182.5 0.0 2.3e-53 181.6 0.0 1.3 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 AEO65442.1 - 6.4e-21 74.3 0.0 1.3e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 FeoC PF09012.5 AEO65442.1 - 0.00031 20.3 0.8 0.00061 19.4 0.0 1.9 2 0 0 2 2 2 1 FeoC like transcriptional regulator zf-C2H2 PF00096.21 AEO65443.1 - 0.0011 19.2 3.7 0.2 12.0 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO65443.1 - 0.0012 19.0 4.6 0.24 11.8 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO65443.1 - 0.0035 17.5 0.6 0.032 14.5 0.0 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-ribbon_3 PF13248.1 AEO65443.1 - 0.028 13.6 0.3 0.05 12.8 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 AEO65443.1 - 0.041 13.7 2.5 4.7 7.2 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 AEO65443.1 - 2.8 7.9 4.4 0.7 9.8 0.2 2.1 2 0 0 2 2 2 0 Zinc ribbon domain DDRGK PF09756.4 AEO65445.1 - 0.31 10.4 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 DDRGK domain Pkr1 PF08636.5 AEO65446.1 - 1.9e-34 117.5 4.2 2.8e-34 116.9 2.9 1.2 1 0 0 1 1 1 1 ER protein Pkr1 LSM PF01423.17 AEO65447.1 - 1e-15 57.0 0.0 1.3e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AEO65447.1 - 2.9e-05 23.8 0.0 4.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF3247 PF11607.3 AEO65447.1 - 0.11 12.7 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) Methyltransf_26 PF13659.1 AEO65448.1 - 1.3e-16 60.6 1.4 2.8e-16 59.5 0.9 1.6 1 1 0 1 1 1 1 Methyltransferase domain eIF-4B PF06273.6 AEO65448.1 - 0.0055 15.5 7.9 0.012 14.4 5.5 1.5 1 0 0 1 1 1 1 Plant specific eukaryotic initiation factor 4B Dicty_REP PF05086.7 AEO65448.1 - 0.19 9.4 0.5 0.24 9.1 0.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med3 PF11593.3 AEO65448.1 - 1.7 7.7 18.8 3 6.9 13.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal M157 PF11624.3 AEO65449.1 - 0.28 10.2 0.2 0.44 9.6 0.1 1.2 1 0 0 1 1 1 0 MHC class I-like protein M157 DLIC PF05783.6 AEO65449.1 - 0.42 9.2 0.4 1.1 7.8 0.1 1.8 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Mt_ATP-synt_B PF05405.9 AEO65450.1 - 4.9e-54 182.1 9.6 6e-54 181.8 6.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) OSCP PF00213.13 AEO65450.1 - 0.15 11.9 7.2 0.23 11.3 5.0 1.3 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Rep_trans PF02486.14 AEO65450.1 - 0.27 10.7 3.7 0.28 10.6 1.9 1.5 1 1 0 1 1 1 0 Replication initiation factor CBF PF03914.12 AEO65451.1 - 3.2e-44 150.2 0.0 7.8e-44 149.0 0.0 1.7 1 0 0 1 1 1 1 CBF/Mak21 family bZIP_Maf PF03131.12 AEO65454.1 - 2.4e-06 27.7 11.8 7.5e-06 26.1 8.2 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.16 AEO65454.1 - 3.9e-05 23.5 20.9 0.00014 21.7 10.5 2.5 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 AEO65454.1 - 0.0011 18.7 13.7 0.0011 18.7 9.5 2.7 1 1 2 3 3 3 1 Basic region leucine zipper Endotoxin_N PF03945.9 AEO65454.1 - 0.055 12.8 4.4 0.1 11.9 3.1 1.4 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Med6 PF04934.9 AEO65454.1 - 0.079 12.4 0.1 0.079 12.4 0.1 2.1 2 0 0 2 2 2 0 MED6 mediator sub complex component DUF342 PF03961.8 AEO65454.1 - 2.3 6.5 13.2 3.4 5.9 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Exonuc_VII_L PF02601.10 AEO65454.1 - 2.4 7.2 12.2 0.54 9.3 6.2 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Sel1 PF08238.7 AEO65455.1 - 1.1e-16 60.8 5.2 1.2e-06 28.9 0.8 4.5 4 0 0 4 4 4 3 Sel1 repeat WD40 PF00400.27 AEO65456.1 - 2.7e-68 223.6 19.7 5.4e-09 35.5 0.1 12.7 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.7 AEO65456.1 - 6e-19 67.9 0.9 1.1e-18 67.1 0.6 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 AEO65456.1 - 9.5e-05 20.7 4.9 0.0017 16.5 0.3 4.1 4 2 0 5 5 5 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AEO65456.1 - 0.00014 20.7 3.3 0.82 8.3 0.1 5.5 2 2 2 7 7 7 1 Nup133 N terminal like eIF2A PF08662.6 AEO65456.1 - 0.055 13.1 0.0 1.8 8.2 0.0 3.5 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A P34-Arc PF04045.9 AEO65457.1 - 1.9e-100 335.1 0.2 2.3e-100 334.8 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Radical_SAM PF04055.16 AEO65457.1 - 0.16 12.1 0.5 4.5 7.4 0.0 2.2 1 1 0 2 2 2 0 Radical SAM superfamily Pyr_redox_3 PF13738.1 AEO65458.1 - 6.7e-27 94.8 0.0 1.3e-26 93.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AEO65458.1 - 5.6e-15 54.5 0.0 5.3e-14 51.3 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 AEO65458.1 - 9.1e-11 41.2 0.0 4.5e-08 32.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 AEO65458.1 - 1.9e-08 34.2 0.0 4.7e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AEO65458.1 - 4e-06 26.8 0.0 3.9e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO65458.1 - 7.1e-05 22.6 0.1 0.00067 19.4 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 AEO65458.1 - 0.015 14.3 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 AEO65458.1 - 0.081 11.3 0.1 0.12 10.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 AEO65458.1 - 0.084 11.7 0.0 0.76 8.6 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase zf-CCCH PF00642.19 AEO65459.1 - 1.5e-09 37.3 28.3 1.1e-05 25.0 0.4 5.4 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HeLo PF14479.1 AEO65459.1 - 0.015 15.0 1.2 0.023 14.4 0.8 1.2 1 0 0 1 1 1 0 Prion-inhibition and propagation TFIIF_beta PF02270.10 AEO65460.1 - 7.5e-73 245.6 3.2 9.4e-73 245.3 2.2 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Tau95 PF09734.4 AEO65460.1 - 0.021 14.1 0.6 0.029 13.6 0.4 1.3 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit PapG_N PF03627.8 AEO65460.1 - 0.14 11.5 0.1 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 PapG carbohydrate binding domain Hydrolase_3 PF08282.7 AEO65461.1 - 0.012 15.1 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.2 AEO65461.1 - 0.038 14.1 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AEO65461.1 - 0.11 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase SNase PF00565.12 AEO65463.1 - 1.8e-22 79.6 0.0 2.5e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Rax2 PF12768.2 AEO65464.1 - 1.9e-88 296.3 4.4 1.7e-80 270.2 0.0 4.9 4 1 0 5 5 5 3 Cortical protein marker for cell polarity Kelch_6 PF13964.1 AEO65464.1 - 0.00061 19.8 10.0 2 8.7 0.2 5.9 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 AEO65464.1 - 0.0078 15.7 0.3 0.33 10.5 0.1 3.6 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 AEO65464.1 - 0.0099 15.6 8.2 0.24 11.1 0.1 4.9 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.10 AEO65464.1 - 0.08 12.7 1.6 7.8 6.4 0.0 4.1 5 0 0 5 5 5 0 Kelch motif Kelch_3 PF13415.1 AEO65464.1 - 3 8.1 22.0 0.11 12.6 0.5 5.8 6 0 0 6 6 6 0 Galactose oxidase, central domain zf-H2C2_2 PF13465.1 AEO65466.1 - 8.7e-11 41.5 11.0 3.8e-05 23.7 0.1 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 AEO65466.1 - 3.5e-10 39.6 10.0 2e-05 24.6 3.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO65466.1 - 1.6e-07 31.1 7.1 0.00021 21.3 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AEO65466.1 - 6.2e-06 25.9 6.2 0.0041 16.9 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 AEO65466.1 - 7e-06 26.0 1.5 2e-05 24.5 1.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AEO65466.1 - 3.6e-05 23.7 4.0 0.00012 22.0 1.4 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 AEO65466.1 - 0.052 13.6 0.3 0.052 13.6 0.2 1.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PAP2 PF01569.16 AEO65466.1 - 1.1 8.9 6.2 0.45 10.2 1.8 2.3 2 1 0 2 2 2 0 PAP2 superfamily SF3b1 PF08920.5 AEO65469.1 - 1.1e-36 126.0 2.3 2.8e-36 124.7 0.0 2.3 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 AEO65469.1 - 1.2e-15 57.5 2.3 0.01 16.1 0.0 7.7 6 3 2 8 8 8 6 HEAT repeats HEAT_EZ PF13513.1 AEO65469.1 - 8.4e-11 42.0 1.4 0.33 11.5 0.0 7.4 6 1 1 7 7 7 2 HEAT-like repeat HEAT PF02985.17 AEO65469.1 - 3.4e-10 39.1 10.1 0.95 9.7 0.0 9.6 10 0 0 10 10 10 3 HEAT repeat Vac14_Fab1_bd PF12755.2 AEO65469.1 - 6.8e-06 26.3 0.8 0.66 10.4 0.0 5.3 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 AEO65469.1 - 0.00012 20.5 0.6 0.016 13.5 0.1 3.1 2 2 1 3 3 3 1 Adaptin N terminal region UPF0236 PF06782.6 AEO65469.1 - 0.0029 16.1 0.1 0.006 15.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0236) CLASP_N PF12348.3 AEO65469.1 - 0.0064 15.8 0.1 1.3 8.3 0.0 3.7 4 0 0 4 4 4 1 CLASP N terminal NUC173 PF08161.7 AEO65469.1 - 0.011 15.1 1.0 6.7 6.0 0.0 4.1 5 0 0 5 5 5 0 NUC173 domain Cnd1 PF12717.2 AEO65469.1 - 0.07 12.9 0.2 62 3.3 0.0 4.3 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HECT_2 PF09814.4 AEO65470.1 - 2e-67 227.4 0.0 2.3e-67 227.2 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding F-box-like PF12937.2 AEO65471.1 - 0.0011 18.6 0.6 0.0029 17.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 AEO65471.1 - 0.0034 17.0 0.2 0.0077 15.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain OGG_N PF07934.7 AEO65472.1 - 1.3e-36 125.0 0.0 2.4e-36 124.2 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 AEO65472.1 - 6.5e-15 55.3 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 AEO65472.1 - 0.0056 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.17 AEO65473.1 - 3.5e-26 90.6 0.1 1e-12 47.4 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO65473.1 - 7.3e-18 64.3 0.0 2.3e-07 30.6 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO65473.1 - 6.7e-14 51.4 0.0 3.7e-05 23.4 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.10 AEO65473.1 - 0.13 12.2 0.0 6.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Smg-4/UPF3 family Ribosomal_S13_N PF08069.7 AEO65474.1 - 1.3e-30 104.9 0.1 2.6e-30 104.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 AEO65474.1 - 6.2e-23 80.3 0.0 1.1e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 AEO65474.1 - 0.014 15.0 0.1 0.036 13.7 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain Dpy-30 PF05186.8 AEO65475.1 - 2.4e-13 49.3 0.0 3.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif DUF605 PF04652.11 AEO65475.1 - 4 6.7 18.5 2.6 7.3 12.0 1.3 2 0 0 2 2 2 0 Vta1 like VRR_NUC PF08774.6 AEO65476.1 - 2.3e-17 62.8 0.0 4.9e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain CDC45 PF02724.9 AEO65477.1 - 0.1 10.5 2.4 0.1 10.5 1.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 AEO65477.1 - 0.18 9.4 0.5 0.22 9.2 0.4 1.0 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 AEO65477.1 - 0.32 10.7 3.3 0.48 10.1 2.3 1.3 1 0 0 1 1 1 0 DDHD domain CAF-1_p150 PF11600.3 AEO65477.1 - 0.47 9.7 17.0 0.8 9.0 11.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Tim54 PF11711.3 AEO65477.1 - 0.56 8.7 6.9 0.84 8.1 4.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF601 PF04642.7 AEO65477.1 - 1.2 8.4 20.0 2.3 7.5 13.6 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF601 Nop14 PF04147.7 AEO65477.1 - 4 5.2 13.8 5.4 4.8 9.5 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.2 AEO65477.1 - 5.1 4.6 6.1 6.4 4.3 4.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CBFB_NFYA PF02045.10 AEO65481.1 - 6.6e-30 103.4 4.3 1.4e-29 102.3 3.0 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B LSM PF01423.17 AEO65482.1 - 1.2e-15 56.8 0.9 1.6e-15 56.4 0.6 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AEO65482.1 - 0.0034 17.2 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.3 AEO65482.1 - 0.026 14.2 0.0 0.059 13.1 0.0 1.5 1 1 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Glutaredoxin2_C PF04399.8 AEO65482.1 - 0.1 12.1 0.1 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain HTH_25 PF13413.1 AEO65482.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.6 1 1 1 2 2 2 0 Helix-turn-helix domain DRMBL PF07522.9 AEO65483.1 - 2.5e-26 91.8 0.0 5.8e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 AEO65483.1 - 1.2e-12 47.7 0.0 2.4e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.10 AEO65483.1 - 0.46 9.3 0.0 19 4.0 0.0 2.1 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II eIF-3_zeta PF05091.7 AEO65484.1 - 4.4e-201 668.9 0.0 5.2e-201 668.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 AEO65484.1 - 0.0099 15.3 0.1 0.026 13.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF569) NUDIX_4 PF14815.1 AEO65484.1 - 0.16 11.4 0.0 4.1 6.8 0.0 2.4 2 0 0 2 2 2 0 NUDIX domain bZIP_1 PF00170.16 AEO65485.1 - 0.0012 18.7 7.9 0.0028 17.5 5.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor Med3 PF11593.3 AEO65485.1 - 0.019 14.2 5.2 5.4 6.1 3.8 2.4 2 1 0 2 2 2 0 Mediator complex subunit 3 fungal Totivirus_coat PF05518.6 AEO65485.1 - 1.6 6.4 5.1 0.33 8.7 0.8 1.7 2 0 0 2 2 2 0 Totivirus coat protein Pkinase PF00069.20 AEO65486.1 - 8.2e-64 215.2 0.0 1.1e-39 136.1 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO65486.1 - 5.2e-28 97.8 0.0 9.3e-21 74.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 AEO65486.1 - 6.3e-10 39.0 0.0 1.4e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 AEO65486.1 - 2.8e-08 33.0 0.0 5.7e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 AEO65486.1 - 7.1e-06 25.9 0.0 0.0029 17.3 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family PAS_9 PF13426.1 AEO65486.1 - 0.002 18.4 0.0 0.0057 17.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain Kdo PF06293.9 AEO65486.1 - 0.015 14.3 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS PF00989.19 AEO65486.1 - 0.019 14.7 0.1 0.088 12.6 0.0 2.2 2 0 0 2 2 2 0 PAS fold Seadorna_VP7 PF07387.6 AEO65486.1 - 0.12 11.1 0.1 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Serglycin PF04360.7 AEO65486.1 - 0.24 11.1 8.0 0.038 13.7 2.5 1.9 2 0 0 2 2 2 0 Serglycin Sugar_tr PF00083.19 AEO65487.1 - 1.5e-23 83.0 23.4 7.3e-13 47.8 6.1 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.13 AEO65488.1 - 8.3e-10 37.9 0.1 3.6e-09 35.8 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO65488.1 - 3.3e-09 36.5 13.9 7.7e-09 35.3 9.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Senescence PF06911.7 AEO65489.1 - 4.2 7.0 25.9 14 5.3 3.4 3.6 1 1 0 2 2 2 0 Senescence-associated protein SNF2_N PF00176.18 AEO65491.1 - 1.4e-32 112.7 0.0 2.6e-30 105.2 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.10 AEO65491.1 - 0.0051 16.6 0.0 0.66 9.7 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AEO65492.1 - 0.022 14.5 0.5 0.049 13.5 0.0 1.8 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Phage_GPD PF05954.6 AEO65494.1 - 0.0048 16.1 0.3 0.0079 15.4 0.2 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) LRR_8 PF13855.1 AEO65494.1 - 0.0049 16.5 2.1 0.15 11.8 0.8 2.8 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 AEO65494.1 - 0.011 15.3 2.9 0.98 9.1 1.9 3.4 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 AEO65494.1 - 1.1 9.4 3.2 5.1 7.4 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 AEO65494.1 - 1.7 9.1 4.4 9.9 6.8 0.0 3.8 4 1 1 5 5 5 0 Leucine rich repeat HSCB_C PF07743.8 AEO65495.1 - 2.2e-17 63.2 3.3 2.2e-17 63.2 2.3 2.3 2 1 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 AEO65495.1 - 4.9e-06 26.1 0.9 5.6e-05 22.7 0.6 2.3 1 1 0 1 1 1 1 DnaJ domain NCD2 PF04905.8 AEO65495.1 - 0.23 11.2 3.1 0.3 10.8 0.1 2.3 2 0 0 2 2 2 0 NAB conserved region 2 (NCD2) DUF3129 PF11327.3 AEO65496.1 - 4.7e-61 205.8 10.7 5.8e-61 205.5 7.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) PCI PF01399.22 AEO65497.1 - 2.6e-12 46.9 0.0 1.7e-11 44.3 0.0 2.2 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 AEO65497.1 - 4.8e-05 22.7 0.1 0.0001 21.7 0.0 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.1 AEO65497.1 - 0.054 13.8 0.4 0.76 10.1 0.1 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Lipase_GDSL_2 PF13472.1 AEO65498.1 - 1.3e-23 84.0 0.0 1.7e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO65498.1 - 6.6e-08 32.6 0.0 1e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Consortin_C PF15281.1 AEO65498.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Consortin C-terminus FMN_dh PF01070.13 AEO65499.1 - 1.4e-88 297.1 0.1 1.9e-88 296.6 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 AEO65499.1 - 6.5e-26 89.9 0.0 1.5e-25 88.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 AEO65499.1 - 6.2e-07 28.6 0.0 9e-07 28.1 0.0 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 AEO65499.1 - 6.9e-07 28.4 0.0 0.0009 18.2 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain ATP11 PF06644.6 AEO65499.1 - 0.00052 19.5 0.0 0.00077 19.0 0.0 1.2 1 0 0 1 1 1 1 ATP11 protein His_biosynth PF00977.16 AEO65499.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.10 AEO65499.1 - 0.084 12.0 0.1 0.16 11.1 0.1 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase DUF3712 PF12505.3 AEO65500.1 - 4.2e-27 94.6 1.7 8.2e-27 93.7 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) DUF2140 PF09911.4 AEO65500.1 - 0.019 14.1 0.3 0.035 13.2 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) WBP-1 PF11669.3 AEO65500.1 - 0.034 14.2 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF4330 PF14221.1 AEO65500.1 - 0.04 13.7 3.5 0.054 13.3 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) HCNGP PF07818.8 AEO65501.1 - 3.1e-13 49.5 0.0 2.2e-05 24.4 0.0 3.1 3 0 0 3 3 3 3 HCNGP-like protein Proteasome PF00227.21 AEO65502.1 - 1e-24 86.9 0.0 2.5e-24 85.6 0.0 1.6 1 1 0 1 1 1 1 Proteasome subunit DUF2567 PF10821.3 AEO65502.1 - 0.017 14.6 0.1 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) Phosphonate-bd PF12974.2 AEO65502.1 - 0.084 12.2 0.2 0.41 9.9 0.0 1.9 1 1 1 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein SIS PF01380.17 AEO65503.1 - 2.3e-56 188.9 0.1 5.9e-30 103.5 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 AEO65503.1 - 9.5e-28 96.9 0.0 8.3e-19 67.5 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 AEO65503.1 - 2e-20 73.1 0.0 4.5e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 AEO65503.1 - 5.7e-11 42.2 0.0 1.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 AEO65503.1 - 8.2e-07 27.9 0.0 1.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 AEO65503.1 - 0.018 14.7 0.0 0.32 10.7 0.0 2.5 2 0 0 2 2 2 0 SIS domain AAA PF00004.24 AEO65504.1 - 4.2e-43 146.7 0.0 8.8e-43 145.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AEO65504.1 - 7.2e-08 32.6 0.0 4.5e-06 26.7 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 AEO65504.1 - 1.4e-06 28.1 0.1 3.7e-05 23.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AEO65504.1 - 2.6e-06 27.4 0.0 7.7e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AEO65504.1 - 2.8e-06 27.4 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 AEO65504.1 - 7.1e-06 25.2 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 AEO65504.1 - 0.00019 20.4 0.0 0.00054 18.9 0.0 1.8 3 0 0 3 3 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 AEO65504.1 - 0.00035 20.2 0.0 0.00079 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 AEO65504.1 - 0.00067 20.4 0.5 0.0023 18.7 0.1 2.2 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 AEO65504.1 - 0.001 18.9 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO65504.1 - 0.0012 19.1 0.3 0.0081 16.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 AEO65504.1 - 0.0015 17.3 0.0 0.0031 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 AEO65504.1 - 0.0016 18.2 0.0 0.0063 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 AEO65504.1 - 0.0024 17.3 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 AEO65504.1 - 0.0032 16.6 0.0 0.0069 15.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 AEO65504.1 - 0.0045 17.1 0.0 0.0096 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 AEO65504.1 - 0.0047 16.0 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_11 PF13086.1 AEO65504.1 - 0.0048 16.5 0.9 0.25 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 AEO65504.1 - 0.0072 15.8 0.0 0.026 13.9 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 AEO65504.1 - 0.0093 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 AEO65504.1 - 0.011 15.2 0.1 0.061 12.7 0.1 2.1 1 1 1 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 AEO65504.1 - 0.016 14.6 0.1 1.4 8.2 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase AAA_24 PF13479.1 AEO65504.1 - 0.017 14.6 0.1 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 AEO65504.1 - 0.022 14.6 0.0 0.062 13.1 0.0 1.8 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.1 AEO65504.1 - 0.022 14.8 0.0 0.064 13.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF4200 PF13863.1 AEO65504.1 - 0.022 14.6 4.1 0.052 13.4 2.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) AAA_28 PF13521.1 AEO65504.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AEO65504.1 - 0.026 14.2 0.3 0.13 11.9 0.0 2.3 2 1 0 2 2 2 0 Archaeal ATPase PhoH PF02562.11 AEO65504.1 - 0.028 13.6 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 AEO65504.1 - 0.032 13.3 0.8 0.11 11.5 0.0 2.3 3 0 0 3 3 3 0 KaiC NACHT PF05729.7 AEO65504.1 - 0.039 13.6 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 AEO65504.1 - 0.046 13.3 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 AEO65504.1 - 0.062 12.1 0.2 0.41 9.4 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.1 AEO65504.1 - 0.081 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain eIF-1a PF01176.14 AEO65504.1 - 0.095 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Parvo_NS1 PF01057.12 AEO65504.1 - 0.096 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 AEO65504.1 - 0.4 10.9 9.4 2.9 8.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain Lactamase_B_2 PF12706.2 AEO65505.1 - 4e-06 26.4 0.1 0.016 14.7 0.0 2.1 1 1 1 2 2 2 2 Beta-lactamase superfamily domain Protoglobin PF11563.3 AEO65506.1 - 3.9e-57 192.3 0.0 4.6e-57 192.1 0.0 1.0 1 0 0 1 1 1 1 Protoglobin Aldedh PF00171.17 AEO65507.1 - 5e-149 496.5 0.0 5.7e-149 496.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Gln-synt_C PF00120.19 AEO65509.1 - 2.3e-63 213.7 0.0 2.8e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 AEO65509.1 - 1.6e-19 69.2 0.0 2.7e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain E1-E2_ATPase PF00122.15 AEO65510.1 - 1e-46 158.8 5.4 1.7e-46 158.1 3.8 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AEO65510.1 - 1.1e-26 94.6 0.0 2e-26 93.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AEO65510.1 - 3.3e-14 53.4 0.0 1e-13 51.9 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AEO65510.1 - 0.00017 21.2 0.1 0.013 15.1 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 AEO65510.1 - 0.00062 19.8 0.0 0.00062 19.8 0.0 2.5 3 0 0 3 3 3 1 Heavy-metal-associated domain S6PP PF05116.8 AEO65510.1 - 0.045 13.0 0.0 18 4.5 0.0 3.0 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase Peptidase_S10 PF00450.17 AEO65510.1 - 0.37 9.9 0.0 0.56 9.2 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase Toxin_12 PF07740.7 AEO65512.1 - 0.00028 21.3 3.7 0.00037 20.9 2.5 1.2 1 0 0 1 1 1 1 Ion channel inhibitory toxin CX PF01705.14 AEO65512.1 - 0.098 12.6 1.2 0.13 12.3 0.8 1.1 1 0 0 1 1 1 0 CX module Toxin_27 PF08099.6 AEO65512.1 - 0.38 10.6 3.0 0.59 10.0 2.1 1.3 1 0 0 1 1 1 0 Scorpion calcine family 3Beta_HSD PF01073.14 AEO65514.1 - 7.3e-25 87.2 0.0 4.5e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AEO65514.1 - 2.3e-14 53.4 0.0 5e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO65514.1 - 1.8e-08 33.6 0.0 6.6e-06 25.2 0.0 2.5 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 AEO65514.1 - 6.4e-08 32.8 0.1 2.6e-05 24.2 0.1 2.7 2 1 0 2 2 2 2 NADH(P)-binding Polysacc_synt_2 PF02719.10 AEO65514.1 - 2.2e-05 23.5 0.0 4.9e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 AEO65514.1 - 0.0001 22.2 0.2 0.00055 19.8 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO65514.1 - 0.0047 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 AEO65514.1 - 0.031 13.1 0.0 0.18 10.6 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain MFS_1 PF07690.11 AEO65515.1 - 4.9e-39 134.0 51.7 3.1e-36 124.8 34.3 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 AEO65515.1 - 8.3e-16 57.2 27.1 1.7e-15 56.2 18.8 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3522 PF12036.3 AEO65515.1 - 1.5 8.6 5.5 0.26 11.0 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3522) Ank_5 PF13857.1 AEO65516.1 - 5.2e-09 36.0 2.2 0.0002 21.5 0.0 5.2 4 1 1 5 5 5 2 Ankyrin repeats (many copies) AAA_16 PF13191.1 AEO65516.1 - 9.3e-09 35.5 4.2 2.9e-08 33.9 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 AEO65516.1 - 1.2e-06 28.6 0.1 8.4e-06 25.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain Ank_2 PF12796.2 AEO65516.1 - 1.5e-05 25.2 0.0 0.00044 20.5 0.0 3.0 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) NACHT PF05729.7 AEO65516.1 - 0.00016 21.3 0.1 0.00054 19.6 0.0 1.9 1 1 0 1 1 1 1 NACHT domain Ank_4 PF13637.1 AEO65516.1 - 0.00026 21.4 2.4 0.29 11.6 0.0 4.3 4 0 0 4 4 3 1 Ankyrin repeats (many copies) Ank PF00023.25 AEO65516.1 - 0.0024 17.6 0.1 23 5.0 0.1 4.7 5 0 0 5 5 5 0 Ankyrin repeat AAA PF00004.24 AEO65516.1 - 0.0028 17.8 0.0 0.0072 16.5 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ank_3 PF13606.1 AEO65516.1 - 0.011 15.8 0.0 25 5.4 0.0 4.7 4 0 0 4 4 3 0 Ankyrin repeat KAP_NTPase PF07693.9 AEO65516.1 - 0.027 13.4 0.1 0.059 12.3 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.1 AEO65516.1 - 0.032 13.9 0.1 0.82 9.4 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain KaiC PF06745.8 AEO65516.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 KaiC MFS_1 PF07690.11 AEO65517.1 - 1.1e-40 139.4 50.1 4.9e-40 137.3 34.9 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO65517.1 - 7.9e-12 44.1 24.4 1.2e-11 43.5 16.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) VWA_3 PF13768.1 AEO65518.1 - 1.5e-29 102.6 0.0 3.6e-29 101.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 AEO65518.1 - 5.1e-19 68.0 0.0 9.7e-19 67.2 0.0 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.1 AEO65518.1 - 3.4e-10 39.2 0.0 1.4e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 AEO65518.1 - 1.5e-09 38.1 0.0 7.5e-09 35.9 0.0 2.2 2 1 1 3 3 3 1 von Willebrand factor type A domain VWA PF00092.23 AEO65518.1 - 0.00017 21.3 0.0 0.0013 18.4 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain PAP2_3 PF14378.1 AEO65519.1 - 1.8e-21 76.5 15.4 3e-19 69.2 2.6 2.9 3 1 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.16 AEO65519.1 - 0.012 15.3 4.6 0.028 14.0 3.0 1.9 1 1 0 1 1 1 0 PAP2 superfamily AreA_N PF07573.6 AEO65519.1 - 0.17 12.4 1.4 11 6.6 0.0 2.5 2 0 0 2 2 2 0 Nitrogen regulatory protein AreA N terminus PAP2_C PF14360.1 AEO65519.1 - 0.39 11.0 2.6 0.4 10.9 0.1 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Daxx PF03344.10 AEO65521.1 - 0.037 12.5 33.8 0.056 11.9 23.5 1.3 1 0 0 1 1 1 0 Daxx Family Tim54 PF11711.3 AEO65521.1 - 9.7 4.6 8.0 17 3.8 5.5 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 HMG_box_2 PF09011.5 AEO65522.1 - 0.0011 19.2 0.1 0.0024 18.1 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 AEO65522.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box DUF1049 PF06305.6 AEO65523.1 - 0.029 13.8 0.1 0.074 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) RskA PF10099.4 AEO65523.1 - 0.1 12.3 0.5 0.16 11.6 0.4 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Asn_synthase PF00733.16 AEO65524.1 - 8.1e-52 176.2 0.0 1.3e-51 175.5 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 AEO65524.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Glyco_hydro_2_N PF02837.13 AEO65527.1 - 2e-28 99.0 0.0 4.5e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 AEO65527.1 - 1.3e-14 53.8 0.0 2.5e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 AEO65527.1 - 5.5e-10 39.6 0.1 1.5e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 AEO65527.1 - 0.0034 17.6 0.2 0.01 16.0 0.1 1.8 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Ank_2 PF12796.2 AEO65528.1 - 3.4e-15 56.1 0.0 3.7e-08 33.5 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 AEO65528.1 - 7.8e-11 41.8 0.3 1.3e-06 28.4 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO65528.1 - 2.1e-10 40.8 0.0 2.1e-05 24.8 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 AEO65528.1 - 1.4e-07 31.0 0.1 4.8e-05 22.9 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 AEO65528.1 - 4.3e-06 26.4 0.0 0.0053 16.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat FAD_binding_3 PF01494.14 AEO65529.1 - 3.2e-18 65.9 0.1 3.2e-11 42.8 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 AEO65529.1 - 8.5e-07 28.1 1.0 1.5e-06 27.3 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AEO65529.1 - 1.8e-06 28.0 0.4 7.2e-06 26.0 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO65529.1 - 3.1e-05 22.6 0.1 0.064 11.7 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.19 AEO65529.1 - 3.5e-05 22.8 4.2 0.0069 15.3 1.1 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 AEO65529.1 - 4.8e-05 22.3 0.4 7e-05 21.8 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 AEO65529.1 - 7.1e-05 22.7 0.8 0.00043 20.2 0.8 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 AEO65529.1 - 9.6e-05 22.7 0.0 0.015 15.6 0.3 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 AEO65529.1 - 0.00038 19.2 0.7 0.094 11.3 0.0 2.4 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 AEO65529.1 - 0.005 16.9 0.2 0.015 15.3 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO65529.1 - 0.007 15.4 2.1 0.046 12.8 1.8 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 AEO65529.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 AEO65529.1 - 0.098 11.5 1.6 0.98 8.2 1.1 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 AEO65529.1 - 0.15 11.4 1.8 0.58 9.5 0.7 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 AEO65529.1 - 0.37 10.6 3.2 1.8 8.3 0.5 2.6 3 0 0 3 3 3 0 ThiF family FAD-oxidase_C PF02913.14 AEO65530.1 - 4.3e-20 72.0 0.0 5.4e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 AEO65530.1 - 1e-18 67.1 0.0 1.8e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain zf-C2H2 PF00096.21 AEO65531.1 - 0.0038 17.4 16.8 0.015 15.5 0.3 4.5 3 1 1 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO65531.1 - 0.0066 16.6 2.1 0.0066 16.6 1.5 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AEO65531.1 - 0.036 14.2 3.9 0.61 10.3 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn_clus PF00172.13 AEO65531.1 - 0.24 11.3 17.6 0.36 10.7 6.9 3.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 AEO65531.1 - 2.2 8.7 29.8 0.12 12.7 0.8 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger Glyco_hydro_61 PF03443.9 AEO65532.1 - 3.2e-44 151.3 0.2 5.2e-44 150.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 AEO65532.1 - 4.3e-13 48.6 17.1 4.3e-13 48.6 11.9 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain TPR_12 PF13424.1 AEO65533.1 - 1.4e-09 37.7 11.0 0.0049 16.7 0.3 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 AEO65533.1 - 3.3e-08 32.8 9.7 1.1 9.3 0.1 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 AEO65533.1 - 1.1e-05 24.8 1.3 0.87 9.5 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 AEO65533.1 - 3.5e-05 23.3 7.9 0.015 14.8 0.1 4.4 2 1 2 4 4 4 2 TPR repeat TPR_16 PF13432.1 AEO65533.1 - 0.00013 22.5 11.0 0.00052 20.6 0.2 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat FIST_C PF10442.4 AEO65533.1 - 0.0003 20.7 0.3 0.0033 17.3 0.2 2.5 2 0 0 2 2 2 1 FIST C domain TPR_14 PF13428.1 AEO65533.1 - 0.00096 19.5 19.8 0.23 12.1 0.1 7.5 6 1 1 7 7 6 1 Tetratricopeptide repeat Ank_2 PF12796.2 AEO65533.1 - 0.0017 18.6 0.0 0.0052 17.0 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) TPR_19 PF14559.1 AEO65533.1 - 0.0019 18.4 6.3 0.16 12.3 0.0 4.1 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 AEO65533.1 - 0.0025 17.4 4.8 0.21 11.5 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat Ank_4 PF13637.1 AEO65533.1 - 0.0036 17.7 0.0 0.015 15.8 0.0 2.0 2 0 0 2 2 1 1 Ankyrin repeats (many copies) HET PF06985.6 AEO65533.1 - 0.0073 16.4 0.1 0.036 14.2 0.0 2.2 2 1 0 3 3 2 1 Heterokaryon incompatibility protein (HET) TPR_1 PF00515.23 AEO65533.1 - 0.017 14.7 7.8 1.5 8.5 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Ank_5 PF13857.1 AEO65533.1 - 0.04 14.1 0.1 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) TPR_17 PF13431.1 AEO65533.1 - 0.046 13.9 0.7 1e+02 3.4 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO65533.1 - 0.12 12.8 11.3 15 6.3 0.1 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 AEO65533.1 - 1.6 9.3 13.6 7 7.3 0.2 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF1668 PF07893.8 AEO65534.1 - 0.018 14.1 1.0 0.15 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) Zn_clus PF00172.13 AEO65535.1 - 8.2e-05 22.4 6.7 0.039 13.8 2.0 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Polyketide_cyc2 PF10604.4 AEO65537.1 - 6.1e-11 42.6 0.0 7.7e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport IRK PF01007.15 AEO65537.1 - 0.12 11.0 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Inward rectifier potassium channel CBM-like PF14683.1 AEO65538.1 - 2.6e-35 121.5 0.0 4.3e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 AEO65538.1 - 2.5e-22 78.7 0.1 1.2e-21 76.5 0.1 2.3 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 AEO65538.1 - 1.9e-07 31.0 0.7 5e-07 29.6 0.3 1.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 AEO65538.1 - 0.0053 16.7 0.1 0.014 15.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) Anp1 PF03452.9 AEO65538.1 - 0.23 10.5 0.6 0.31 10.1 0.4 1.1 1 0 0 1 1 1 0 Anp1 Lsm_C PF14894.1 AEO65539.1 - 0.34 10.4 1.5 2 8.0 0.1 2.1 2 0 0 2 2 2 0 Lsm C-terminal Glyco_hydro_17 PF00332.13 AEO65540.1 - 2e-10 40.2 0.1 7.5e-08 31.7 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Serglycin PF04360.7 AEO65540.1 - 3.9 7.1 7.6 11 5.7 5.3 1.7 1 0 0 1 1 1 0 Serglycin Amidoligase_2 PF12224.3 AEO65541.1 - 2.7e-12 46.8 0.0 2.7e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 Putative amidoligase enzyme MFS_1 PF07690.11 AEO65543.1 - 1.7e-23 82.9 46.0 1.7e-23 82.9 31.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO65543.1 - 1.5e-21 76.2 27.3 2e-21 75.8 18.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3759 PF12585.3 AEO65544.1 - 1.7e-37 127.2 4.7 2.1e-37 126.9 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) AKAP_110 PF05716.8 AEO65544.1 - 0.03 12.3 0.1 0.031 12.2 0.1 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) Mor PF08765.6 AEO65544.1 - 0.093 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Mor transcription activator family DUF1275 PF06912.6 AEO65546.1 - 2.1e-38 131.6 14.7 2.7e-38 131.2 10.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) NYAP_C PF15452.1 AEO65546.1 - 0.031 13.2 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter AAA PF00004.24 AEO65547.1 - 1.4e-18 67.3 0.0 2.8e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AEO65547.1 - 8e-05 23.4 0.0 8e-05 23.4 0.0 3.2 3 1 1 4 4 3 1 AAA domain RuvB_N PF05496.7 AEO65547.1 - 0.00069 18.7 0.0 0.0017 17.4 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AEO65547.1 - 0.0013 18.7 0.0 0.0036 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AEO65547.1 - 0.0018 18.4 0.3 0.011 15.9 0.0 2.2 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 AEO65547.1 - 0.0083 16.4 0.0 0.0083 16.4 0.0 3.0 2 1 0 2 2 1 1 AAA domain SR-25 PF10500.4 AEO65547.1 - 0.017 14.6 17.2 0.03 13.8 11.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_19 PF13245.1 AEO65547.1 - 0.021 14.5 0.1 0.051 13.3 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 AEO65547.1 - 0.032 13.9 0.1 0.089 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ResIII PF04851.10 AEO65547.1 - 0.065 13.0 1.8 39 3.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.1 AEO65547.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 AEO65547.1 - 0.12 11.9 2.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain RR_TM4-6 PF06459.7 AEO65547.1 - 1.8 8.4 12.8 3 7.6 8.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.5 AEO65547.1 - 8.3 6.3 16.9 18 5.3 11.7 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 zf-RING_2 PF13639.1 AEO65548.1 - 8.3e-09 35.1 4.2 8.3e-09 35.1 2.9 2.3 3 0 0 3 3 3 1 Ring finger domain FANCL_C PF11793.3 AEO65548.1 - 4e-05 23.4 7.8 0.00014 21.7 5.4 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.2 AEO65548.1 - 0.0097 15.9 2.3 0.0097 15.9 1.6 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 AEO65548.1 - 0.022 14.4 4.2 0.022 14.4 2.9 2.0 2 0 0 2 2 2 0 zinc-RING finger domain SWIM PF04434.12 AEO65548.1 - 0.031 13.7 0.3 0.071 12.5 0.2 1.6 1 0 0 1 1 1 0 SWIM zinc finger RINGv PF12906.2 AEO65548.1 - 0.088 12.8 5.8 0.2 11.7 4.0 1.6 1 0 0 1 1 1 0 RING-variant domain zf-Apc11 PF12861.2 AEO65548.1 - 0.29 10.9 8.8 0.24 11.2 3.6 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 AEO65548.1 - 1.5 8.8 11.3 0.054 13.5 3.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1996 PF09362.5 AEO65549.1 - 8.1e-86 287.4 4.4 9.3e-86 287.2 3.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AAA_12 PF13087.1 AEO65550.1 - 3.8e-36 124.3 0.0 6.9e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 AEO65550.1 - 3e-25 89.1 3.0 3.4e-25 88.9 0.2 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AEO65550.1 - 1.2e-09 37.8 0.3 3.9e-09 36.1 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 AEO65550.1 - 2.6e-08 33.6 0.2 1.8e-05 24.3 0.0 3.3 2 1 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 AEO65550.1 - 0.0035 16.9 0.0 0.28 10.6 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Herpes_U30 PF04523.8 AEO65550.1 - 0.0091 13.5 0.0 0.014 12.8 0.0 1.2 1 0 0 1 1 1 1 Herpes virus tegument protein U30 PhoH PF02562.11 AEO65550.1 - 0.021 14.0 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 AEO65550.1 - 0.087 11.7 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.27 AEO65551.1 - 1.3e-21 75.6 1.5 0.00059 19.6 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat SAPS PF04499.10 AEO65551.1 - 0.73 8.4 1.7 1.2 7.7 1.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 AEO65551.1 - 1.8 6.4 11.5 2.3 6.1 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 AEO65552.1 - 4.4e-33 111.9 2.2 3.6e-12 45.6 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat PUL PF08324.6 AEO65553.1 - 3.7e-54 183.3 0.0 4.9e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 AEO65553.1 - 1.6e-43 147.4 0.2 3.7e-43 146.2 0.1 1.7 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 AEO65553.1 - 1.8e-36 122.6 15.5 1.3e-07 31.1 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 AEO65553.1 - 0.005 16.6 0.1 5.3 6.8 0.0 4.1 4 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region SRR1 PF07985.7 AEO65555.1 - 0.0005 19.9 0.0 0.0008 19.2 0.0 1.3 1 0 0 1 1 1 1 SRR1 CDC45 PF02724.9 AEO65557.1 - 0.17 9.8 3.3 0.15 10.0 2.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Dsh_C PF12316.3 AEO65557.1 - 6.7 6.7 8.0 7.8 6.5 5.6 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal PAN_4 PF14295.1 AEO65558.1 - 4.2e-05 23.1 3.4 9.7e-05 22.0 2.3 1.6 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 AEO65558.1 - 0.024 14.4 2.7 0.039 13.7 1.9 1.3 1 0 0 1 1 1 0 PAN-like domain Epimerase PF01370.16 AEO65559.1 - 4.2e-08 32.9 0.0 6.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO65559.1 - 4.4e-08 33.3 0.0 8.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 AEO65559.1 - 0.00019 20.4 0.0 0.00035 19.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 AEO65559.1 - 0.00046 20.4 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 AEO65559.1 - 0.0088 14.7 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 AEO65559.1 - 0.021 14.7 0.0 0.088 12.7 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 AEO65559.1 - 0.074 11.9 0.0 0.23 10.2 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.8 AEO65559.1 - 0.094 11.9 0.0 0.19 10.9 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family Polysacc_synt_2 PF02719.10 AEO65559.1 - 0.18 10.6 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Myb_DNA-binding PF00249.26 AEO65561.1 - 8.7e-31 105.7 4.2 1.2e-12 47.6 0.2 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO65561.1 - 1.1e-30 105.4 3.8 6.6e-16 58.1 0.1 3.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 AEO65561.1 - 0.0077 16.4 0.9 0.99 9.6 0.1 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like MFS_1 PF07690.11 AEO65563.1 - 1.9e-26 92.6 33.8 7.5e-23 80.7 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RNase_H2-Ydr279 PF09468.5 AEO65565.1 - 0.43 9.7 2.0 0.72 8.9 1.4 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) zf-met PF12874.2 AEO65566.1 - 0.00055 20.0 1.8 0.12 12.5 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AEO65566.1 - 0.0028 17.7 5.3 0.89 9.7 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 AEO65566.1 - 0.018 15.3 0.8 0.018 15.3 0.6 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Herpes_capsid PF06112.6 AEO65566.1 - 0.43 10.6 6.1 0.61 10.1 4.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein zf-C2H2 PF00096.21 AEO65566.1 - 1.2 9.6 12.0 2 8.9 0.4 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Mut7-C PF01927.11 AEO65566.1 - 1.4 8.8 4.8 0.69 9.8 1.8 1.7 1 1 0 1 1 1 0 Mut7-C RNAse domain zf-C2H2_4 PF13894.1 AEO65566.1 - 1.8 9.1 15.9 0.64 10.4 0.8 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger DUF1610 PF07754.6 AEO65566.1 - 5.7 7.1 12.1 0.2 11.8 2.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Fungal_trans PF04082.13 AEO65567.1 - 2.1e-25 89.0 2.1 3.5e-25 88.3 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO65567.1 - 5.5e-08 32.6 13.1 1.1e-07 31.6 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brr6_like_C_C PF10104.4 AEO65568.1 - 2.2e-41 140.5 0.0 2.8e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Med26 PF08711.6 AEO65569.1 - 1.9e-13 49.7 0.0 3.3e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pkinase PF00069.20 AEO65570.1 - 1e-42 146.0 0.3 3.2e-25 88.7 0.1 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO65570.1 - 6.6e-15 54.8 0.2 2.4e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.1 AEO65572.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 CutA1 PF03091.10 AEO65572.1 - 0.076 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Tyrosinase PF00264.15 AEO65574.1 - 4.1e-49 167.7 0.0 5e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Serglycin PF04360.7 AEO65574.1 - 0.03 14.0 3.8 0.068 12.9 2.7 1.5 1 0 0 1 1 1 0 Serglycin DnaJ PF00226.26 AEO65575.1 - 5.5e-19 67.6 2.1 5.5e-19 67.6 1.5 2.5 2 0 0 2 2 2 1 DnaJ domain Atg14 PF10186.4 AEO65575.1 - 8.6 5.2 13.5 17 4.2 9.4 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RRM_1 PF00076.17 AEO65576.1 - 7.9e-11 41.4 0.0 1.3e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO65576.1 - 2.2e-09 37.0 0.0 4.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO65576.1 - 4.3e-07 29.8 0.0 7.8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO65576.1 - 0.0013 18.4 0.1 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 AEO65576.1 - 0.023 14.5 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif Sterol_MT_C PF08498.5 AEO65577.1 - 3.3e-29 100.6 0.4 5.5e-29 99.9 0.3 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 AEO65577.1 - 4e-22 78.5 0.0 8.6e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO65577.1 - 1.2e-18 67.1 0.0 1.7e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO65577.1 - 2.1e-14 53.7 0.0 4.1e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO65577.1 - 2.9e-14 53.0 0.0 4.9e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AEO65577.1 - 3.7e-14 52.4 0.0 5.7e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 AEO65577.1 - 2.8e-13 50.1 0.1 9.8e-13 48.4 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO65577.1 - 5.5e-12 46.2 0.0 2.1e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO65577.1 - 1.8e-11 43.6 0.0 3.9e-11 42.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AEO65577.1 - 7e-11 42.1 0.0 2.1e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO65577.1 - 2.1e-06 27.2 0.0 4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 AEO65577.1 - 9.1e-05 21.7 0.0 0.00021 20.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 AEO65577.1 - 0.00023 20.7 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 AEO65577.1 - 0.00062 19.3 0.0 0.0015 18.1 0.0 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.7 AEO65577.1 - 0.0016 17.8 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.15 AEO65577.1 - 0.0023 17.0 0.0 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 AEO65577.1 - 0.0036 18.1 0.0 0.015 16.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 AEO65577.1 - 0.01 15.0 0.4 0.019 14.1 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_29 PF03141.11 AEO65577.1 - 0.013 13.8 0.0 0.023 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.1 AEO65577.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 AEO65577.1 - 0.019 14.5 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 IF3_N PF05198.11 AEO65577.1 - 0.022 14.6 0.1 0.056 13.3 0.0 1.6 2 0 0 2 2 1 0 Translation initiation factor IF-3, N-terminal domain TehB PF03848.9 AEO65577.1 - 0.12 11.5 0.0 0.31 10.1 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB Transket_pyr PF02779.19 AEO65578.1 - 1.5e-45 154.8 0.0 2.1e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 AEO65578.1 - 8.1e-36 122.6 0.1 2.2e-35 121.2 0.1 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Aminotran_5 PF00266.14 AEO65578.1 - 0.077 11.7 0.0 0.18 10.4 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class-V Glyco_hydro_61 PF03443.9 AEO65580.1 - 6.9e-51 173.1 0.1 7.8e-51 172.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Parecho_VpG PF06344.6 AEO65580.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Parechovirus Genome-linked protein GSu_C4xC__C2xCH PF09698.5 AEO65580.1 - 0.28 11.3 4.4 0.55 10.4 0.4 2.9 2 0 0 2 2 2 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) TYA PF01021.14 AEO65581.1 - 0.3 11.3 7.3 0.66 10.1 5.0 1.6 1 0 0 1 1 1 0 TYA transposon protein Mucin PF01456.12 AEO65581.1 - 4.4 7.0 17.6 0.36 10.6 8.8 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF914 PF06027.7 AEO65582.1 - 9.3e-99 330.4 16.0 1.2e-98 330.0 11.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 AEO65582.1 - 1.9e-05 24.7 25.1 0.00024 21.1 4.8 2.4 2 1 0 2 2 2 2 EamA-like transporter family FUSC-like PF12805.2 AEO65582.1 - 0.0016 17.4 0.7 0.0016 17.4 0.5 2.2 2 0 0 2 2 2 1 FUSC-like inner membrane protein yccS TPT PF03151.11 AEO65582.1 - 5.5 6.6 23.8 0.56 9.8 1.0 2.7 3 0 0 3 3 3 0 Triose-phosphate Transporter family Golgin_A5 PF09787.4 AEO65584.1 - 0.61 8.5 2.0 0.77 8.2 1.4 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 PAP_assoc PF03828.14 AEO65585.1 - 1.6e-16 60.0 0.2 3.1e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 AEO65585.1 - 3.7e-06 27.1 0.0 7.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Abhydrolase_1 PF00561.15 AEO65587.1 - 3e-17 62.9 0.1 6.4e-17 61.8 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AEO65587.1 - 9.5e-11 42.0 9.5 3.4e-09 36.9 6.6 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 AEO65587.1 - 0.00047 19.6 0.0 0.00074 19.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase MFS_1 PF07690.11 AEO65589.1 - 2e-14 53.0 58.6 8.3e-13 47.7 17.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NUDIX PF00293.23 AEO65591.1 - 9.1e-05 22.1 0.4 0.00016 21.2 0.3 1.4 1 0 0 1 1 1 1 NUDIX domain Ribosomal_60s PF00428.14 AEO65591.1 - 0.042 14.2 1.4 0.11 12.9 1.0 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3042 PF11240.3 AEO65593.1 - 0.06 13.1 1.4 0.16 11.8 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) SKG6 PF08693.5 AEO65593.1 - 0.28 10.5 5.1 0.82 9.0 3.5 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PBP1_TM PF14812.1 AEO65593.1 - 2.2 8.6 4.4 2.8 8.2 0.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GST_N_3 PF13417.1 AEO65594.1 - 3.7e-24 84.7 0.2 3.5e-23 81.6 0.1 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO65594.1 - 6.2e-18 64.5 0.0 1.4e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO65594.1 - 2.3e-08 33.8 0.5 8.1e-08 32.0 0.3 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AEO65594.1 - 1.2e-05 25.3 0.0 0.0026 17.9 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 AEO65594.1 - 0.0015 18.4 0.0 0.0043 16.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SR-25 PF10500.4 AEO65594.1 - 4.8 6.5 6.8 7.6 5.9 4.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SIR2 PF02146.12 AEO65595.1 - 1.9e-54 184.0 0.0 2.6e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 AEO65595.1 - 0.0042 16.8 0.2 0.084 12.6 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain HTH_Tnp_1 PF01527.15 AEO65595.1 - 0.026 14.4 0.5 0.052 13.5 0.3 1.5 1 0 0 1 1 1 0 Transposase DMPK_coil PF08826.5 AEO65595.1 - 0.081 12.8 0.3 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 DMPK coiled coil domain like zf-LYAR PF08790.6 AEO65595.1 - 0.15 11.8 0.3 0.36 10.5 0.2 1.6 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Podoplanin PF05808.6 AEO65597.1 - 0.0004 19.9 3.5 0.00063 19.3 2.4 1.3 1 0 0 1 1 1 1 Podoplanin cEGF PF12662.2 AEO65597.1 - 1.7 8.3 14.2 4.4 7.0 1.0 3.5 3 0 0 3 3 3 0 Complement Clr-like EGF-like Lamp PF01299.12 AEO65597.1 - 8 5.5 16.8 0.31 10.1 0.1 2.6 2 1 1 3 3 3 0 Lysosome-associated membrane glycoprotein (Lamp) FHA PF00498.21 AEO65598.1 - 1.6e-16 60.1 0.0 4.2e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 FHA domain XhlA PF10779.4 AEO65598.1 - 5.2 7.0 7.9 18 5.3 2.8 2.8 2 0 0 2 2 2 0 Haemolysin XhlA Romo1 PF10247.4 AEO65599.1 - 2e-29 101.5 11.5 2.5e-29 101.2 8.0 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Spore_YabQ PF09578.5 AEO65599.1 - 0.36 10.8 3.6 0.69 9.9 0.5 2.0 1 1 1 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) Cu-oxidase_3 PF07732.10 AEO65600.1 - 6.1e-42 142.0 7.9 1.6e-41 140.7 0.3 3.1 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 AEO65600.1 - 1e-33 116.5 0.1 6.4e-32 110.6 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 AEO65600.1 - 2.3e-31 108.1 1.7 2.3e-31 108.1 1.2 3.5 3 1 0 3 3 3 1 Multicopper oxidase TP_methylase PF00590.15 AEO65601.1 - 2e-43 148.5 0.0 7.1e-43 146.7 0.0 2.0 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.1 AEO65601.1 - 6e-08 31.8 0.2 3e-06 26.4 0.0 2.6 3 0 0 3 3 3 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.1 AEO65601.1 - 1.3e-06 28.5 0.0 3.6e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 AEO65601.1 - 0.00015 20.6 0.0 0.00027 19.8 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Ras PF00071.17 AEO65602.1 - 2.3e-54 183.1 0.0 2.7e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO65602.1 - 3.7e-16 59.7 0.0 5.2e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO65602.1 - 3e-09 36.3 0.0 5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AEO65602.1 - 0.0005 19.2 0.0 0.00057 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 AEO65602.1 - 0.0045 16.2 0.0 0.0063 15.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AEO65602.1 - 0.0097 15.8 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 AEO65602.1 - 0.01 14.5 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.22 AEO65602.1 - 0.089 13.0 0.0 0.15 12.3 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 AEO65602.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase CWC25 PF12542.3 AEO65603.1 - 1.4e-27 95.9 0.6 1.4e-27 95.9 0.4 3.9 4 2 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 AEO65603.1 - 4.7e-10 39.3 4.3 4.7e-10 39.3 3.0 4.8 4 1 2 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR PCI PF01399.22 AEO65604.1 - 6.4e-17 61.7 0.7 2.5e-16 59.8 0.0 2.3 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 AEO65604.1 - 2.7e-06 27.2 0.9 7.8e-06 25.7 0.6 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_10 PF13374.1 AEO65604.1 - 0.00038 20.2 2.5 1.7 8.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 AEO65604.1 - 0.15 11.7 2.1 1.7 8.3 0.3 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 AEO65604.1 - 0.15 12.0 8.1 0.49 10.3 0.2 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 AEO65604.1 - 0.24 11.2 5.4 4.3 7.3 0.2 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 AEO65604.1 - 0.58 10.0 4.9 0.28 11.0 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 AEO65604.1 - 1.6 8.7 9.2 0.47 10.4 0.3 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 AEO65604.1 - 8 7.2 8.3 26 5.6 0.0 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Peptidase_C65 PF10275.4 AEO65607.1 - 9.8e-72 241.2 0.0 1.3e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain BPL_LplA_LipB PF03099.14 AEO65608.1 - 1.2e-05 25.3 0.0 4e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Rsm22 PF09243.5 AEO65609.1 - 1.6e-32 112.6 0.0 1.2e-31 109.7 0.0 2.3 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 AEO65609.1 - 0.00019 21.1 0.0 0.00039 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO65609.1 - 0.015 15.8 0.6 0.095 13.2 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 AEO65609.1 - 0.037 14.4 0.0 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Thioredoxin PF00085.15 AEO65610.1 - 7.1e-14 51.3 0.0 9e-14 51.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AEO65610.1 - 0.0016 18.6 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.6 AEO65610.1 - 0.044 13.6 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF2763 PF10961.3 AEO65610.1 - 0.15 12.4 0.0 0.15 12.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2763) Na_Ala_symp PF01235.12 AEO65610.1 - 0.96 7.9 3.7 1.3 7.5 2.5 1.1 1 0 0 1 1 1 0 Sodium:alanine symporter family Methyltrn_RNA_3 PF02598.12 AEO65611.1 - 1.8e-85 286.8 0.0 2e-85 286.6 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 AEO65611.1 - 0.00049 19.9 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 2 SpoU rRNA Methylase family Fungal_trans_2 PF11951.3 AEO65613.1 - 7.9e-39 133.3 1.0 1e-38 132.9 0.7 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 AEO65614.1 - 8.5e-15 55.2 1.1 1.4e-14 54.5 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO65614.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 AEO65614.1 - 4.8e-05 23.0 0.0 6.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 AEO65614.1 - 6.9e-05 22.5 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AEO65614.1 - 0.00049 19.3 0.0 0.012 14.8 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 AEO65614.1 - 0.084 11.3 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) HET PF06985.6 AEO65615.1 - 3.9e-33 114.5 0.4 6.6e-33 113.8 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Epimerase PF01370.16 AEO65616.1 - 3.9e-09 36.3 0.2 0.0013 18.2 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO65616.1 - 0.00055 18.7 0.1 0.0015 17.2 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 AEO65616.1 - 0.0033 16.6 0.2 0.0085 15.3 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 AEO65616.1 - 0.006 16.6 0.7 0.063 13.2 0.5 2.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 AEO65616.1 - 0.0075 15.2 0.4 0.21 10.4 0.0 2.4 2 1 0 3 3 3 1 Male sterility protein Polyketide_cyc2 PF10604.4 AEO65617.1 - 6.2e-06 26.4 0.0 1.2e-05 25.5 0.0 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 AEO65617.1 - 1.2e-05 25.3 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport 4HBT PF03061.17 AEO65619.1 - 0.0072 16.4 0.3 0.026 14.6 0.0 2.1 2 0 0 2 2 2 1 Thioesterase superfamily RVP PF00077.15 AEO65620.1 - 0.08 12.8 0.0 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Retroviral aspartyl protease Antimicrobial_8 PF08103.6 AEO65620.1 - 0.13 12.2 0.3 0.31 11.0 0.2 1.6 1 0 0 1 1 1 0 Uperin family Pkinase PF00069.20 AEO65621.1 - 4.4e-17 62.0 0.0 3e-11 42.9 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO65621.1 - 1.4e-09 37.3 0.0 9e-07 28.2 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase TFIIA PF03153.8 AEO65622.1 - 0.097 12.5 14.0 0.2 11.5 9.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit API5 PF05918.6 AEO65622.1 - 0.48 8.8 3.2 0.69 8.3 2.2 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) CPSase_L_D2 PF02786.12 AEO65623.1 - 1.3e-74 250.0 0.0 2e-74 249.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 AEO65623.1 - 3.4e-35 120.2 0.0 6.5e-35 119.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 AEO65623.1 - 4.6e-34 116.8 0.0 1e-33 115.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 AEO65623.1 - 1.4e-19 70.5 0.2 4.1e-19 69.0 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AEO65623.1 - 2.1e-14 53.0 0.0 3.5e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 AEO65623.1 - 2.9e-08 33.3 0.0 6.1e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 AEO65623.1 - 5.6e-08 32.3 0.0 9.9e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 AEO65623.1 - 4.8e-06 26.5 0.0 8.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 AEO65623.1 - 0.014 14.8 0.0 0.33 10.3 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.1 AEO65623.1 - 0.082 12.5 0.0 0.29 10.8 0.0 2.0 1 0 0 1 1 1 0 Biotin-lipoyl like ATPgrasp_ST PF14397.1 AEO65623.1 - 0.19 10.8 0.0 0.65 9.0 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Pyridox_oxidase PF01243.15 AEO65624.1 - 1.3e-13 50.7 0.0 2.8e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Gpi16 PF04113.9 AEO65624.1 - 0.021 12.8 0.1 0.026 12.5 0.0 1.0 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component Pyridox_ox_2 PF12900.2 AEO65624.1 - 0.08 12.7 0.0 0.17 11.7 0.0 1.5 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Mem_trans PF03547.13 AEO65625.1 - 5.5e-42 143.4 0.0 5e-35 120.5 0.0 2.2 2 0 0 2 2 2 2 Membrane transport protein Pkinase PF00069.20 AEO65626.1 - 8.1e-50 169.3 0.0 1.1e-46 159.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO65626.1 - 2.8e-30 105.2 0.0 1.1e-28 99.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO65626.1 - 0.00092 18.2 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 AEO65626.1 - 0.0017 17.2 0.1 0.0028 16.5 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Phostensin_N PF13916.1 AEO65626.1 - 0.0028 17.5 2.9 0.036 14.0 0.2 2.5 2 0 0 2 2 2 1 PP1-regulatory protein, Phostensin N-terminal Pox_ser-thr_kin PF05445.6 AEO65626.1 - 0.092 11.5 0.1 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SUR7 PF06687.7 AEO65627.1 - 1.1e-26 93.7 5.2 2.2e-26 92.7 3.6 1.5 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 AEO65627.1 - 0.0006 19.5 9.0 0.0006 19.5 6.2 1.5 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Trp_oprn_chp PF09534.5 AEO65627.1 - 1.5 8.3 15.7 3.6 7.1 10.9 1.6 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Laminin_EGF PF00053.19 AEO65628.1 - 0.31 10.9 6.7 0.71 9.8 4.7 1.5 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) Zn_clus PF00172.13 AEO65628.1 - 5.5 6.9 12.4 9.6 6.2 8.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Serglycin PF04360.7 AEO65628.1 - 6.5 6.4 6.5 13 5.4 4.5 1.4 1 0 0 1 1 1 0 Serglycin MFS_1 PF07690.11 AEO65629.1 - 3.4e-44 150.9 42.3 3.4e-44 150.9 29.3 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 AEO65629.1 - 0.0021 16.2 1.4 0.0021 16.2 1.0 2.4 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family ACPS PF01648.15 AEO65630.1 - 9.3e-07 28.6 0.0 3.9e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily COX17 PF05051.8 AEO65630.1 - 0.045 13.7 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Peptidase_A22B PF04258.8 AEO65631.1 - 2.8e-46 158.3 10.0 6.7e-45 153.8 6.9 2.6 1 1 0 1 1 1 1 Signal peptide peptidase SSP160 PF06933.6 AEO65631.1 - 0.57 8.1 21.5 0.87 7.4 14.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 AEO65631.1 - 3.7 5.2 9.4 4.9 4.7 6.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 AEO65631.1 - 5.4 6.8 15.4 13 5.5 10.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Med31 PF05669.7 AEO65632.1 - 1.9e-36 123.9 0.7 2.1e-36 123.7 0.5 1.0 1 0 0 1 1 1 1 SOH1 TFIIS_C PF01096.13 AEO65633.1 - 1.6e-12 46.8 0.4 1.6e-12 46.8 0.3 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 AEO65633.1 - 0.011 15.3 0.6 0.029 14.0 0.0 1.9 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-C2HC PF01530.13 AEO65633.1 - 0.44 10.3 0.3 0.44 10.3 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C2HC type Ank_2 PF12796.2 AEO65634.1 - 2.8e-16 59.6 0.0 1e-08 35.3 0.0 2.3 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AEO65634.1 - 1e-10 41.8 0.0 4.4e-06 27.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 AEO65634.1 - 1.1e-09 37.6 0.3 0.0077 15.9 0.0 4.0 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 AEO65634.1 - 3.6e-08 32.8 0.1 0.08 13.2 0.0 3.9 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 AEO65634.1 - 6.9e-08 32.4 0.1 0.19 12.0 0.0 4.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) DUF2090 PF09863.4 AEO65634.1 - 0.034 13.0 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) BRI3BP PF14965.1 AEO65635.1 - 0.0028 17.0 0.0 0.0036 16.6 0.0 1.1 1 0 0 1 1 1 1 Negative regulator of p53/TP53 HSP70 PF00012.15 AEO65636.1 - 1.2e-09 36.6 0.1 1.2e-09 36.6 0.1 2.3 3 0 0 3 3 3 2 Hsp70 protein zf-SAP30 PF13866.1 AEO65636.1 - 0.0043 16.6 0.1 0.0098 15.5 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 AEO65636.1 - 0.033 12.7 0.1 0.16 10.5 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein NPCBM_assoc PF10633.4 AEO65637.1 - 0.063 13.3 0.5 1.8 8.7 0.1 2.3 1 1 1 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Hexokinase_1 PF00349.16 AEO65638.1 - 2e-65 219.9 0.0 3e-65 219.3 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 AEO65638.1 - 3.8e-63 212.9 0.0 6.6e-63 212.1 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Acetyltransf_1 PF00583.19 AEO65639.1 - 2.7e-05 24.1 0.0 4.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Sgf11 PF08209.6 AEO65641.1 - 2.7 7.3 7.9 0.2 10.9 2.2 1.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Pro_isomerase PF00160.16 AEO65642.1 - 8e-51 172.3 0.0 9.6e-51 172.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.20 AEO65643.1 - 1.1e-05 24.7 0.0 1.2e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain DUF1876 PF08962.6 AEO65643.1 - 0.036 13.8 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) SOBP PF15279.1 AEO65644.1 - 0.6 10.4 4.7 0.53 10.6 3.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Oxysterol_BP PF01237.13 AEO65645.1 - 9.3e-129 428.9 0.0 2.5e-128 427.5 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 AEO65645.1 - 8.1e-19 67.7 0.0 2.8e-12 46.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AEO65645.1 - 1.1e-17 62.8 0.1 1.9e-06 27.3 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 AEO65645.1 - 2.1e-17 63.1 0.5 2.9e-08 33.9 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO65645.1 - 2.3e-17 62.6 0.6 6.4e-10 38.9 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO65645.1 - 3.6e-15 54.5 0.2 3.4e-05 23.6 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.24 AEO65645.1 - 7.6e-12 45.3 0.3 1.4e-11 44.4 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 AEO65645.1 - 6.6e-10 39.2 1.0 1.7e-09 37.9 0.7 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 AEO65645.1 - 7.4e-08 32.3 0.6 1.7e-07 31.1 0.4 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain 4HBT_3 PF13622.1 AEO65646.1 - 8.3e-50 169.8 4.4 1.3e-49 169.2 3.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 AEO65646.1 - 6e-22 77.6 0.0 1.8e-11 43.8 0.0 3.6 3 1 0 3 3 3 3 Acyl-CoA thioesterase 4HBT PF03061.17 AEO65646.1 - 0.012 15.7 0.1 0.25 11.4 0.1 2.3 2 0 0 2 2 2 0 Thioesterase superfamily zf-C3H1 PF10650.4 AEO65647.1 - 2.2e-08 33.3 3.7 3.5e-08 32.7 2.6 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain Gly-zipper_OmpA PF13436.1 AEO65648.1 - 0.029 14.0 3.3 0.031 13.9 2.3 1.2 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain HR1 PF02185.11 AEO65648.1 - 0.068 12.9 2.4 0.089 12.5 1.7 1.2 1 0 0 1 1 1 0 Hr1 repeat DUF3886 PF13025.1 AEO65648.1 - 0.18 11.8 10.3 0.23 11.4 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) TMF_DNA_bd PF12329.3 AEO65648.1 - 0.19 11.5 5.2 0.25 11.1 3.6 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.3 AEO65648.1 - 0.22 10.7 1.5 0.27 10.4 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF591 PF04569.9 AEO65648.1 - 0.26 11.3 11.1 0.33 11.0 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function Pox_A_type_inc PF04508.7 AEO65648.1 - 2.8 7.9 9.4 5.2 7.1 4.0 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Atrophin-1 PF03154.10 AEO65648.1 - 3.2 5.7 4.5 3.4 5.6 3.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family EST1_DNA_bind PF10373.4 AEO65649.1 - 7.5e-17 61.4 0.0 3.4e-15 56.0 0.0 2.2 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain Gly_transf_sug PF04488.10 AEO65653.1 - 1.9e-13 50.6 0.0 3.5e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif AMP-binding PF00501.23 AEO65654.1 - 1.7e-85 286.9 0.0 2.1e-85 286.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO65654.1 - 5.2e-16 59.3 0.0 1.9e-15 57.5 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 AEO65656.1 - 1e-34 119.8 2.7 1.4e-34 119.4 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO65656.1 - 6.2e-17 62.1 0.1 7.8e-17 61.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO65656.1 - 9.7e-13 48.1 0.6 1.5e-12 47.5 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO65656.1 - 4.3e-06 26.3 0.0 7.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 AEO65656.1 - 2.9e-05 23.7 0.4 4.6e-05 23.1 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 AEO65656.1 - 0.00032 19.7 0.1 0.00043 19.2 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 AEO65656.1 - 0.00047 19.8 1.3 0.0015 18.2 0.5 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.14 AEO65656.1 - 0.00048 18.9 0.0 0.00065 18.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 AEO65656.1 - 0.00059 19.8 0.4 0.00097 19.1 0.3 1.4 1 0 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 AEO65656.1 - 0.0028 16.8 0.1 0.0048 16.0 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 AEO65656.1 - 0.004 16.0 0.0 0.0061 15.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 AEO65656.1 - 0.009 16.0 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain DFP PF04127.10 AEO65656.1 - 0.012 15.2 0.5 0.021 14.4 0.4 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NmrA PF05368.8 AEO65656.1 - 0.015 14.5 0.5 0.036 13.3 0.4 1.6 1 0 0 1 1 1 0 NmrA-like family F420_oxidored PF03807.12 AEO65656.1 - 0.027 14.8 0.1 0.054 13.9 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.14 AEO65656.1 - 0.033 13.2 0.1 0.087 11.8 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Urocanase PF01175.13 AEO65656.1 - 0.038 12.0 0.2 0.061 11.3 0.2 1.3 1 0 0 1 1 1 0 Urocanase AdoHcyase_NAD PF00670.16 AEO65656.1 - 0.042 13.6 0.8 0.096 12.5 0.4 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DapB_N PF01113.15 AEO65656.1 - 0.049 13.5 0.1 0.46 10.4 0.1 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ThiF PF00899.16 AEO65657.1 - 7.3e-35 119.7 0.0 1.3e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.1 AEO65657.1 - 0.0095 16.1 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Glyco_hydro_17 PF00332.13 AEO65657.1 - 0.063 12.3 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 TrkA_N PF02254.13 AEO65657.1 - 0.082 12.9 0.2 0.37 10.8 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Saccharop_dh PF03435.13 AEO65657.1 - 0.1 11.5 0.7 0.65 8.9 0.5 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase ApbA PF02558.11 AEO65657.1 - 0.16 11.4 0.4 0.33 10.3 0.3 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RTC PF01137.16 AEO65658.1 - 1.2e-39 135.4 0.0 1.7e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase DUF3486 PF11985.3 AEO65660.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3486) QRPTase_C PF01729.14 AEO65661.1 - 2.1e-55 186.8 0.2 2.5e-55 186.5 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 AEO65661.1 - 5.6e-23 80.5 0.0 1.7e-22 79.0 0.0 1.9 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain B12-binding PF02310.14 AEO65661.1 - 0.021 14.6 0.1 0.037 13.8 0.1 1.3 1 0 0 1 1 1 0 B12 binding domain IGPS PF00218.16 AEO65661.1 - 0.095 11.7 0.2 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase RCC1 PF00415.13 AEO65662.1 - 5.1e-56 186.6 9.1 7.1e-14 51.7 0.1 7.8 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AEO65662.1 - 7.8e-39 130.4 28.1 2.1e-09 36.7 0.9 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.6 AEO65662.1 - 0.016 14.3 0.1 3.2 6.8 0.0 3.1 4 0 0 4 4 4 0 TUP1-like enhancer of split DUF1811 PF08838.5 AEO65662.1 - 0.1 12.5 0.0 2.9 7.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) DUF619 PF04768.8 AEO65663.1 - 2.6e-48 163.6 0.1 4.4e-48 162.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 AEO65663.1 - 1.1e-30 106.4 0.0 4.5e-30 104.4 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 AEO65663.1 - 7.4e-29 100.9 0.0 1.4e-28 100.0 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 AEO65663.1 - 0.03 14.2 0.0 0.073 12.9 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.16 AEO65664.1 - 2.4e-24 84.7 2.0 2.9e-24 84.4 1.4 1.1 1 0 0 1 1 1 1 Synaptobrevin LOH1CR12 PF10158.4 AEO65664.1 - 0.042 13.6 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Tumour suppressor protein UPF0184 PF03670.8 AEO65664.1 - 0.056 13.6 0.4 0.093 12.9 0.3 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) DUF883 PF05957.8 AEO65664.1 - 0.07 13.5 0.4 0.12 12.7 0.2 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Radical_SAM PF04055.16 AEO65665.1 - 4.5e-16 59.4 0.0 6.4e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Ribosomal_S14 PF00253.16 AEO65666.1 - 5.3e-18 64.1 0.5 1.2e-17 63.0 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Arb2 PF09757.4 AEO65667.1 - 4.8e-20 71.7 0.0 7.1e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain WD40 PF00400.27 AEO65669.1 - 6.4e-14 51.2 14.0 2.6e-06 27.0 0.3 6.0 5 1 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.1 AEO65669.1 - 0.0031 17.7 0.1 2.4 8.5 0.0 3.4 3 0 0 3 3 3 2 PQQ-like domain Fungal_trans_2 PF11951.3 AEO65671.1 - 0.00016 20.3 0.1 0.00033 19.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRM_1 PF00076.17 AEO65672.1 - 8e-19 67.0 0.0 2.3e-13 49.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO65672.1 - 3.3e-13 49.3 0.0 2e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO65672.1 - 0.024 14.5 0.0 5 7.0 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 AEO65673.1 - 1e-22 80.8 0.5 4.1e-13 49.5 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 AEO65673.1 - 6.7e-11 42.1 0.1 1.7e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 AEO65673.1 - 1.4e-05 24.9 0.1 0.0046 16.7 0.0 2.6 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 AEO65673.1 - 0.059 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 AEO65673.1 - 0.067 12.6 0.1 0.86 8.9 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Atrophin-1 PF03154.10 AEO65673.1 - 2.9 5.9 9.8 4 5.4 6.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family Semialdhyde_dhC PF02774.13 AEO65674.1 - 1.6e-40 138.8 0.0 2.1e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 AEO65674.1 - 2.9e-28 98.5 0.0 7.8e-28 97.2 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 AEO65674.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 AEO65674.1 - 0.099 13.1 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold RhoGAP PF00620.22 AEO65675.1 - 3.3e-49 166.3 0.0 8.9e-49 164.9 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 AEO65675.1 - 1.8e-16 60.0 0.8 4e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4407 PF14362.1 AEO65675.1 - 1.7 7.5 9.5 4 6.3 6.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1620 PF07774.8 AEO65676.1 - 3e-67 226.0 0.0 4.4e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 AEO65676.1 - 7.3e-13 48.5 8.9 2.6e-10 40.1 2.4 3.1 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 AEO65676.1 - 7.2e-06 25.2 0.9 0.01 15.3 0.0 4.2 4 0 0 4 4 4 1 PQQ enzyme repeat LRR_8 PF13855.1 AEO65677.1 - 3.4e-12 45.9 12.8 2e-07 30.6 2.5 2.3 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 AEO65677.1 - 2.4e-10 39.8 8.6 7.6e-09 35.0 1.3 3.1 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AEO65677.1 - 1.6e-06 27.3 7.2 0.91 9.8 0.0 4.6 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 AEO65677.1 - 0.0011 18.8 3.3 10 6.8 0.0 4.2 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 AEO65677.1 - 1.2 9.4 4.8 5.7 7.3 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeat TFIIF_alpha PF05793.7 AEO65678.1 - 9.8 4.4 11.2 14 3.9 7.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) tRNA-synt_2 PF00152.15 AEO65679.1 - 2e-74 250.4 0.0 2.6e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AEO65679.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Borrelia_P83 PF05262.6 AEO65679.1 - 0.2 9.9 7.0 0.29 9.3 4.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein NARP1 PF12569.3 AEO65679.1 - 0.23 10.1 7.3 0.34 9.5 5.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF885 PF05960.6 AEO65679.1 - 0.52 9.3 6.0 1.1 8.3 2.9 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) DUF2058 PF09831.4 AEO65679.1 - 1.1 9.0 10.9 1.9 8.3 7.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) SIP1 PF04938.7 AEO65680.1 - 2.5e-05 23.7 0.1 0.021 14.2 0.0 3.1 3 0 0 3 3 3 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) RNR_inhib PF08591.5 AEO65681.1 - 1.3e-22 80.5 2.1 1.5e-22 80.2 0.1 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor Ribosomal_S27e PF01667.12 AEO65682.1 - 2.2e-28 97.5 7.4 2.7e-28 97.2 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 AEO65682.1 - 0.011 15.5 1.4 0.013 15.3 1.0 1.2 1 0 0 1 1 1 0 IBR domain TF_Zn_Ribbon PF08271.7 AEO65682.1 - 0.29 10.4 3.3 0.41 10.0 2.3 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Phosducin PF02114.11 AEO65683.1 - 6.7e-13 47.9 0.0 9.4e-13 47.4 0.0 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 AEO65683.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin DUF3503 PF12011.3 AEO65683.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3503) Raptor_N PF14538.1 AEO65684.1 - 2.3e-64 215.8 0.0 4.5e-64 214.9 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 AEO65684.1 - 1.6e-09 37.2 1.1 1.3 8.9 0.0 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 AEO65684.1 - 8.5e-06 25.5 0.2 0.0072 16.0 0.1 2.5 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.17 AEO65684.1 - 4.4e-05 23.2 0.1 1.3 9.2 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 AEO65684.1 - 0.0042 17.3 0.5 1.2 9.4 0.0 3.4 3 1 0 3 3 3 1 HEAT repeats Atx10homo_assoc PF09759.4 AEO65684.1 - 0.074 12.7 0.1 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Cnd1 PF12717.2 AEO65684.1 - 0.19 11.5 0.2 15 5.3 0.0 3.3 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Kelch_4 PF13418.1 AEO65685.1 - 4e-12 45.7 0.1 0.00011 21.9 0.0 2.6 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.1 AEO65685.1 - 4.7e-11 42.3 0.2 0.00038 20.3 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 AEO65685.1 - 7e-10 38.8 7.3 9.7e-08 31.9 0.1 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 AEO65685.1 - 1.2e-09 37.5 0.0 7.9e-05 22.1 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 AEO65685.1 - 2.9e-05 24.0 0.0 0.35 11.1 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 AEO65685.1 - 3e-05 23.5 0.0 0.064 13.0 0.0 2.6 2 0 0 2 2 2 2 Kelch motif SlyX PF04102.7 AEO65685.1 - 0.13 12.6 0.1 0.13 12.6 0.1 8.4 7 2 0 8 8 8 0 SlyX Mpv17_PMP22 PF04117.7 AEO65686.1 - 1.5e-12 46.9 0.5 1.5e-12 46.9 0.4 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family YIF1 PF03878.10 AEO65687.1 - 9.7e-74 247.5 2.0 1.2e-73 247.1 1.4 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 AEO65687.1 - 0.00017 21.1 4.9 0.00017 21.1 3.4 1.5 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.8 AEO65688.1 - 1.4e-77 260.7 0.0 1.9e-77 260.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 AEO65688.1 - 3.5e-07 30.2 0.1 1.8e-06 27.9 0.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CinA PF02464.12 AEO65688.1 - 0.0022 17.4 0.3 0.0046 16.4 0.2 1.4 1 0 0 1 1 1 1 Competence-damaged protein PI3_PI4_kinase PF00454.22 AEO65689.1 - 6.1e-50 169.8 0.0 1.2e-49 168.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 AEO65689.1 - 2.6e-41 141.8 1.0 5e-41 140.8 0.4 1.7 2 0 0 2 2 2 1 FAT domain SRP54 PF00448.17 AEO65689.1 - 3.4e-32 111.5 0.0 6.8e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UME PF08064.8 AEO65689.1 - 4.5e-31 106.9 0.1 2.5e-30 104.5 0.0 2.4 2 0 0 2 2 2 1 UME (NUC010) domain zf-PARP PF00645.13 AEO65689.1 - 8.7e-19 67.5 0.4 2.1e-18 66.3 0.3 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region ArgK PF03308.11 AEO65689.1 - 0.00075 18.3 0.1 0.0016 17.2 0.0 1.5 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 AEO65689.1 - 0.012 15.0 0.1 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 AEO65689.1 - 0.062 13.0 0.3 0.44 10.2 0.0 2.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 AEO65689.1 - 0.15 12.0 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Med17 PF10156.4 AEO65691.1 - 7.9e-88 294.7 0.0 9e-88 294.5 0.0 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.15 AEO65692.1 - 1.3e-162 539.4 0.4 2.9e-119 397.2 0.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.14 AEO65692.1 - 0.0051 16.2 0.3 0.016 14.6 0.2 1.9 1 0 0 1 1 1 1 UvrB/uvrC motif DUF4381 PF14316.1 AEO65693.1 - 0.065 13.3 0.2 0.076 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RVT_1 PF00078.22 AEO65694.1 - 0.003 16.9 0.2 0.0032 16.8 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exonuc_V_gamma PF04257.9 AEO65694.1 - 0.02 12.8 1.2 0.024 12.6 0.8 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit VSP PF03302.8 AEO65695.1 - 0.0094 14.6 0.8 0.014 14.0 0.5 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.6 AEO65695.1 - 0.01 15.3 0.2 0.02 14.4 0.2 1.4 1 0 0 1 1 1 0 Podoplanin Rax2 PF12768.2 AEO65695.1 - 0.018 14.2 0.0 0.039 13.1 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.5 AEO65695.1 - 0.1 11.9 0.6 0.23 10.8 0.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SNF2_N PF00176.18 AEO65696.1 - 4.1e-65 219.5 0.2 6.5e-65 218.8 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO65696.1 - 2.1e-12 46.7 0.0 5.2e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 AEO65696.1 - 4.9e-09 35.7 4.4 8e-09 35.0 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO65696.1 - 1e-06 28.4 7.0 1.8e-06 27.6 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AEO65696.1 - 5.7e-06 25.8 7.1 1e-05 25.0 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO65696.1 - 8.1e-06 25.7 7.6 1.5e-05 24.9 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 AEO65696.1 - 7.5e-05 22.2 0.1 0.00024 20.6 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 AEO65696.1 - 0.0001 22.1 3.3 0.0006 19.6 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.1 AEO65696.1 - 0.00035 20.2 6.9 0.00063 19.4 4.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AEO65696.1 - 0.0078 16.0 8.7 0.017 14.9 6.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 AEO65696.1 - 0.19 11.4 0.4 0.39 10.4 0.3 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_UBOX PF13445.1 AEO65696.1 - 0.3 10.8 4.3 0.66 9.7 3.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 AEO65696.1 - 0.85 9.2 6.6 2.3 7.8 4.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Phosphodiest PF01663.17 AEO65697.1 - 7.5e-92 308.4 0.9 9.5e-92 308.1 0.6 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 AEO65697.1 - 0.0081 15.3 0.3 0.64 9.1 0.2 2.3 1 1 0 1 1 1 1 Sulfatase PglZ PF08665.7 AEO65697.1 - 0.033 13.8 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 PglZ domain DUF4106 PF13388.1 AEO65697.1 - 0.57 9.0 2.4 0.97 8.3 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Ribosomal_L14e PF01929.12 AEO65699.1 - 2.6e-29 101.3 2.7 3.7e-29 100.8 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 NAC PF01849.13 AEO65700.1 - 1.8e-25 88.2 0.4 1.8e-24 85.0 0.1 2.5 2 0 0 2 2 2 1 NAC domain Mt_ATP-synt_D PF05873.7 AEO65700.1 - 1.5e-18 66.9 1.2 2.5e-18 66.2 0.5 1.5 1 1 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) UBA PF00627.26 AEO65700.1 - 0.0017 18.1 0.1 0.0053 16.5 0.1 2.0 1 0 0 1 1 1 1 UBA/TS-N domain T2SM_b PF10741.4 AEO65700.1 - 0.13 11.8 1.6 2.2 7.9 0.0 2.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b COX16 PF14138.1 AEO65701.1 - 4e-32 110.2 0.1 5.6e-32 109.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Peptidase_M49 PF03571.10 AEO65702.1 - 1.7e-221 736.1 0.0 2e-221 735.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Glucosamine_iso PF01182.15 AEO65702.1 - 0.036 13.7 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SKI PF01202.17 AEO65703.1 - 8.8e-15 54.9 0.0 1.2e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 AEO65703.1 - 6.6e-12 45.4 0.0 9.2e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO65703.1 - 6.3e-11 43.1 0.0 8.5e-11 42.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO65703.1 - 1.9e-09 37.9 0.0 3.4e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 AEO65703.1 - 2.4e-05 24.5 0.0 9.3e-05 22.6 0.0 1.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO65703.1 - 9.9e-05 22.4 0.0 0.00017 21.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 AEO65703.1 - 0.00022 20.0 0.0 0.00031 19.5 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 AEO65703.1 - 0.00044 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 AEO65703.1 - 0.00051 20.0 0.0 0.001 19.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 AEO65703.1 - 0.0012 19.0 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 AEO65703.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 AEO65703.1 - 0.004 17.4 0.0 0.0069 16.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_5 PF07728.9 AEO65703.1 - 0.0045 16.7 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 AEO65703.1 - 0.0061 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AEO65703.1 - 0.0073 16.1 0.0 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 AEO65703.1 - 0.008 15.3 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.1 AEO65703.1 - 0.0087 15.9 0.0 0.079 12.8 0.0 2.1 1 1 0 1 1 1 1 Cytidylate kinase-like family ANF_receptor PF01094.23 AEO65703.1 - 0.0091 14.8 0.0 0.014 14.1 0.0 1.4 1 1 0 1 1 1 1 Receptor family ligand binding region Viral_helicase1 PF01443.13 AEO65703.1 - 0.013 15.0 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 AEO65703.1 - 0.014 14.5 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 AEO65703.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase APS_kinase PF01583.15 AEO65703.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.1 AEO65703.1 - 0.019 14.5 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 AEO65703.1 - 0.02 13.7 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 AEO65703.1 - 0.025 14.1 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CoaE PF01121.15 AEO65703.1 - 0.03 13.7 0.0 0.088 12.2 0.0 1.8 2 0 0 2 2 2 0 Dephospho-CoA kinase PRK PF00485.13 AEO65703.1 - 0.031 13.8 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.10 AEO65703.1 - 0.035 13.8 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 AEO65703.1 - 0.043 12.6 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.1 AEO65703.1 - 0.044 13.3 0.0 0.044 13.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 AEO65703.1 - 0.063 12.6 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ADK PF00406.17 AEO65703.1 - 0.073 12.9 0.1 2.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase Thymidylate_kin PF02223.12 AEO65703.1 - 0.081 12.2 0.0 5.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase DUF2075 PF09848.4 AEO65703.1 - 0.086 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 AEO65703.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain CobU PF02283.11 AEO65703.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase MobB PF03205.9 AEO65703.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RuvB_N PF05496.7 AEO65703.1 - 0.13 11.2 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus 2-oxoacid_dh PF00198.18 AEO65704.1 - 7.2e-72 241.3 0.0 1.9e-71 239.9 0.0 1.7 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 AEO65704.1 - 1.6e-17 62.8 0.1 2.8e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 AEO65704.1 - 6.4e-13 48.1 0.0 2.5e-12 46.2 0.0 2.1 1 0 0 1 1 1 1 e3 binding domain ATP-synt_10 PF05176.9 AEO65705.1 - 3.6e-88 295.1 0.0 4.5e-88 294.7 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein V-SNARE_C PF12352.3 AEO65706.1 - 8.9e-11 41.7 0.1 8.9e-11 41.7 0.1 2.7 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus STAT_alpha PF01017.15 AEO65706.1 - 0.028 14.1 4.0 0.18 11.5 1.8 2.4 2 1 0 2 2 2 0 STAT protein, all-alpha domain Adaptin_binding PF10199.4 AEO65706.1 - 0.13 12.5 2.0 0.2 11.9 1.4 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 SATase_N PF06426.9 AEO65706.1 - 0.31 11.2 3.9 0.61 10.3 0.9 2.4 1 1 0 2 2 2 0 Serine acetyltransferase, N-terminal APG6 PF04111.7 AEO65706.1 - 0.38 9.7 7.5 0.31 10.0 4.4 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Adeno_PIX PF03955.9 AEO65706.1 - 2.3 8.8 7.9 4.2 7.9 1.6 2.4 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) FTCD_C PF04961.7 AEO65706.1 - 2.8 7.3 6.5 3 7.2 0.7 2.1 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase CorA PF01544.13 AEO65706.1 - 6.9 5.6 11.2 3.6 6.5 4.1 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Mod_r PF07200.8 AEO65706.1 - 7.5 6.4 10.1 3.3 7.6 1.5 2.6 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Ribosomal_L6e PF01159.14 AEO65707.1 - 2.6e-37 127.3 0.2 4.1e-37 126.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Gmx_para_CXXCG PF09535.5 AEO65707.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) Ribosomal_L29 PF00831.18 AEO65708.1 - 1.2e-17 63.3 1.6 1.2e-17 63.3 1.1 1.9 2 1 1 3 3 3 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 AEO65708.1 - 0.008 16.4 0.3 0.0095 16.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Cortex-I_coil PF09304.5 AEO65708.1 - 0.019 14.9 1.0 0.019 14.9 0.7 1.6 2 0 0 2 2 2 0 Cortexillin I, coiled coil Snapin_Pallidin PF14712.1 AEO65708.1 - 1.3 9.3 4.9 0.49 10.7 1.4 1.7 1 1 1 2 2 2 0 Snapin/Pallidin STT3 PF02516.9 AEO65709.1 - 1.3e-130 436.6 36.6 1.5e-125 419.9 24.6 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT PF02366.13 AEO65709.1 - 0.00026 20.4 14.7 0.00026 20.4 10.2 2.9 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Cytomega_TRL10 PF06084.6 AEO65709.1 - 0.2 11.4 1.3 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Pkinase PF00069.20 AEO65710.1 - 1e-66 224.7 0.0 1.7e-66 224.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO65710.1 - 4.4e-30 104.6 0.0 8e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 AEO65710.1 - 1.1e-10 41.4 0.0 8.6e-09 35.4 0.0 2.6 2 0 0 2 2 2 1 FHA domain APH PF01636.18 AEO65710.1 - 0.0012 18.6 0.2 0.62 9.7 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family KfrA_N PF11740.3 AEO65710.1 - 0.0019 18.6 1.1 0.43 11.0 0.0 3.1 3 0 0 3 3 3 1 Plasmid replication region DNA-binding N-term Kinase-like PF14531.1 AEO65710.1 - 0.0039 16.2 0.0 0.0087 15.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 AEO65710.1 - 0.0084 15.1 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TraF_2 PF13729.1 AEO65710.1 - 0.1 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Pox_ser-thr_kin PF05445.6 AEO65710.1 - 0.66 8.7 0.1 1.1 8.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SpoIIE PF07228.7 AEO65712.1 - 0.00043 20.0 0.2 0.0086 15.8 0.0 2.3 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 AEO65712.1 - 0.0011 18.3 0.0 0.0027 17.1 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Fcf1 PF04900.7 AEO65713.1 - 2e-21 75.9 0.0 3.1e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Fcf1 DUF726 PF05277.7 AEO65714.1 - 4.9e-127 423.5 2.5 6.8e-127 423.0 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Integrin_alpha PF00357.15 AEO65714.1 - 1.1 9.2 3.2 2.6 8.0 2.3 1.7 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region V-ATPase_H_N PF03224.9 AEO65715.1 - 9.9e-73 244.9 0.0 1.3e-72 244.6 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 AEO65715.1 - 1.5e-38 131.4 0.0 3.7e-38 130.0 0.0 1.7 1 0 0 1 1 1 1 V-ATPase subunit H TMEM51 PF15345.1 AEO65716.1 - 0.12 12.0 3.0 6.5 6.3 0.1 2.2 1 1 1 2 2 2 0 Transmembrane protein 51 DUF1469 PF07332.6 AEO65716.1 - 1.7 8.4 0.0 1.7 8.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Ribosomal_L6 PF00347.18 AEO65717.1 - 2.8e-26 91.8 8.1 9.1e-14 51.7 2.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Vps26 PF03643.10 AEO65718.1 - 4.1e-131 435.7 0.6 4.8e-131 435.5 0.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 AEO65718.1 - 6.2e-05 22.8 0.0 0.19 11.5 0.0 3.5 1 1 1 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Nup160 PF11715.3 AEO65719.1 - 7.8e-157 522.6 0.0 1.5e-156 521.7 0.0 1.4 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Strep_SA_rep PF06696.6 AEO65719.1 - 0.053 13.3 0.2 2.8 7.8 0.1 2.7 2 0 0 2 2 2 0 Streptococcal surface antigen repeat DIOX_N PF14226.1 AEO65722.1 - 0.0049 17.3 0.0 0.0068 16.9 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal EF-hand_1 PF00036.27 AEO65724.1 - 2.3e-27 92.1 5.8 1.1e-06 27.5 0.1 5.4 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 AEO65724.1 - 1.2e-24 86.1 8.0 6e-10 39.1 0.6 3.6 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 AEO65724.1 - 5.5e-22 75.6 7.0 7.9e-05 22.2 0.1 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 AEO65724.1 - 1.4e-20 72.5 11.3 1.2e-09 37.6 0.0 5.1 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 AEO65724.1 - 1.7e-18 65.0 8.1 2.8e-05 23.2 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 AEO65724.1 - 0.033 14.1 0.5 0.3 11.0 0.0 2.7 3 1 0 3 3 3 0 EF-hand domain EF-hand_10 PF14788.1 AEO65724.1 - 0.095 12.3 0.2 9.9 5.9 0.0 3.1 2 1 1 3 3 3 0 EF hand EF-hand_2 PF09068.6 AEO65724.1 - 0.13 12.2 0.0 73 3.4 0.0 3.6 3 1 1 4 4 4 0 EF hand ChaC PF04752.7 AEO65725.1 - 9.7e-52 175.5 0.0 1.4e-51 174.9 0.0 1.3 1 0 0 1 1 1 1 ChaC-like protein HpcH_HpaI PF03328.9 AEO65728.1 - 9.7e-39 132.5 0.5 8.7e-38 129.4 0.1 2.0 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 AEO65728.1 - 9.6e-16 57.5 0.0 3.5e-07 29.3 0.1 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF846 PF05832.7 AEO65729.1 - 1.5e-52 177.0 9.2 1.8e-52 176.8 6.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) YwiC PF14256.1 AEO65729.1 - 0.1 12.6 10.2 0.47 10.5 1.3 2.2 2 0 0 2 2 2 0 YwiC-like protein DUF4191 PF13829.1 AEO65729.1 - 4.9 6.2 10.4 4.9 6.1 1.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) BPD_transp_1 PF00528.17 AEO65729.1 - 6.1 6.3 14.9 0.29 10.6 4.3 2.2 2 0 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component SKG6 PF08693.5 AEO65730.1 - 1.1e-05 24.6 1.1 2.5e-05 23.4 0.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.8 AEO65730.1 - 0.0031 16.1 0.2 0.0045 15.6 0.2 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Rax2 PF12768.2 AEO65730.1 - 0.0051 16.0 0.0 0.0079 15.4 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Herpes_gE PF02480.11 AEO65730.1 - 0.03 12.6 0.0 0.049 11.9 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Hep_59 PF07052.6 AEO65731.1 - 1.3e-17 64.0 0.4 1.3e-17 64.0 0.3 2.7 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 WD40 PF00400.27 AEO65734.1 - 1.1e-22 78.9 9.5 1.1e-06 28.3 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 AEO65734.1 - 0.00041 18.6 0.4 0.0022 16.2 0.3 2.0 2 1 0 2 2 2 1 Nucleoporin Nup120/160 NST1 PF13945.1 AEO65734.1 - 0.41 10.6 9.8 0.34 10.9 1.8 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator GCV_T PF01571.16 AEO65735.1 - 1.9e-61 207.1 0.0 2.6e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 AEO65735.1 - 1.2e-21 76.4 0.5 2.6e-21 75.4 0.3 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Choline_kinase PF01633.15 AEO65736.1 - 4.8e-55 186.4 0.0 4.2e-54 183.3 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 AEO65736.1 - 4.1e-13 49.6 1.3 3.5e-12 46.5 0.9 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 AEO65736.1 - 0.036 13.2 0.0 0.12 11.4 0.0 1.8 1 1 0 1 1 1 0 Ecdysteroid kinase NPR3 PF03666.8 AEO65737.1 - 7.7e-149 496.0 0.0 9.9e-149 495.7 0.0 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 SecA_PP_bind PF01043.15 AEO65737.1 - 0.1 12.9 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 SecA preprotein cross-linking domain NPR2 PF06218.6 AEO65737.1 - 0.11 11.1 0.1 0.22 10.1 0.0 1.4 1 0 0 1 1 1 0 Nitrogen permease regulator 2 HLH PF00010.21 AEO65738.1 - 1.9e-12 46.6 0.0 5e-12 45.3 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_60s PF00428.14 AEO65738.1 - 0.58 10.5 3.7 2.4 8.6 0.1 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Got1 PF04178.7 AEO65739.1 - 3.4e-28 98.1 14.3 4.4e-28 97.7 9.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 AEO65739.1 - 0.081 11.8 0.0 0.14 11.0 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M50 Claudin_2 PF13903.1 AEO65739.1 - 9.3 5.9 11.6 53 3.4 5.4 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction La PF05383.12 AEO65740.1 - 5.2e-17 61.3 0.0 9e-17 60.6 0.0 1.4 1 0 0 1 1 1 1 La domain Corona_nucleoca PF00937.13 AEO65741.1 - 0.0031 16.5 5.0 0.0031 16.5 3.5 4.7 3 1 0 4 4 4 3 Coronavirus nucleocapsid protein TPR_14 PF13428.1 AEO65742.1 - 1.4e-27 93.6 23.4 1e-05 25.7 0.1 12.6 8 2 6 14 14 13 6 Tetratricopeptide repeat TPR_19 PF14559.1 AEO65742.1 - 1.1e-24 86.5 1.8 3e-07 30.6 0.0 7.5 6 1 0 7 7 7 4 Tetratricopeptide repeat HAT PF02184.11 AEO65742.1 - 5.4e-22 77.2 67.1 2e-10 40.2 0.8 12.9 14 0 0 14 14 14 4 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 AEO65742.1 - 2.4e-20 72.6 22.7 0.0034 18.0 0.0 9.2 10 1 0 10 10 8 6 Tetratricopeptide repeat Suf PF05843.9 AEO65742.1 - 1.5e-16 60.9 12.1 7.2e-05 22.6 0.0 6.6 3 1 1 5 5 5 4 Suppressor of forked protein (Suf) TPR_15 PF13429.1 AEO65742.1 - 2e-09 36.9 10.8 0.00076 18.6 0.5 5.7 2 1 3 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 AEO65742.1 - 2.5e-09 36.9 13.8 0.034 14.0 0.0 8.6 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.1 AEO65742.1 - 5.6e-08 32.3 11.5 0.026 14.1 0.2 6.3 7 0 0 7 7 7 3 TPR repeat TPR_6 PF13174.1 AEO65742.1 - 5.8e-08 32.6 17.1 0.18 12.3 0.0 9.5 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_17 PF13431.1 AEO65742.1 - 2.9e-07 30.1 8.3 0.18 12.1 0.0 7.5 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 AEO65742.1 - 7.9e-06 25.4 23.3 0.0076 16.0 0.1 8.8 10 0 0 10 10 10 2 Tetratricopeptide repeat U3_assoc_6 PF08640.6 AEO65742.1 - 3.4e-05 23.5 15.6 0.024 14.3 1.5 5.9 3 2 1 5 5 5 2 U3 small nucleolar RNA-associated protein 6 Fis1_TPR_C PF14853.1 AEO65742.1 - 0.00038 20.2 16.0 0.47 10.3 0.0 6.3 7 0 0 7 7 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 AEO65742.1 - 0.00056 19.5 0.0 12 5.9 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 AEO65742.1 - 0.0022 17.7 5.7 0.87 9.4 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 AEO65742.1 - 0.0054 16.2 5.9 3.1 7.5 0.0 5.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 AEO65742.1 - 0.1 12.4 16.6 13 5.8 0.0 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.5 AEO65742.1 - 0.11 12.6 2.4 2.6 8.2 0.1 3.7 3 0 0 3 3 3 0 c-SKI Smad4 binding domain NRDE-2 PF08424.5 AEO65742.1 - 0.84 8.4 32.6 0.44 9.3 0.0 5.9 4 2 1 6 6 6 0 NRDE-2, necessary for RNA interference Prp31_C PF09785.4 AEO65743.1 - 2.2e-42 144.3 0.4 5.1e-42 143.2 0.3 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 AEO65743.1 - 1.5e-40 137.9 0.5 2.5e-40 137.1 0.0 1.6 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 AEO65743.1 - 3.9e-22 77.7 0.1 5.5e-21 74.1 0.0 2.2 2 0 0 2 2 2 1 NOSIC (NUC001) domain HLH PF00010.21 AEO65744.1 - 0.00019 21.0 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain zf-C2H2_4 PF13894.1 AEO65745.1 - 7e-05 22.8 4.0 0.00032 20.8 0.2 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO65745.1 - 0.00058 20.0 5.8 0.0048 17.1 0.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO65745.1 - 0.0011 19.1 1.7 0.0011 19.1 1.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain Integrin_B_tail PF07965.7 AEO65745.1 - 0.049 14.0 0.0 0.1 13.0 0.0 1.5 1 1 0 1 1 1 0 Integrin beta tail domain Acetate_kinase PF00871.12 AEO65746.1 - 1.7e-84 283.6 0.0 2.3e-84 283.2 0.0 1.2 1 0 0 1 1 1 1 Acetokinase family Transformer PF06495.6 AEO65747.1 - 0.0046 16.8 3.2 0.0087 15.9 2.2 1.4 1 0 0 1 1 1 1 Fruit fly transformer protein Peptidase_C37 PF05416.7 AEO65747.1 - 0.068 11.4 0.4 0.46 8.7 0.2 1.9 2 0 0 2 2 2 0 Southampton virus-type processing peptidase Sugar_tr PF00083.19 AEO65748.1 - 4.3e-33 114.5 27.0 4.3e-21 75.0 3.4 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 AEO65748.1 - 3.6e-23 81.8 18.7 2.8e-17 62.4 7.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily HTH_23 PF13384.1 AEO65748.1 - 6.7e-07 28.7 1.4 1.9e-06 27.3 0.4 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 AEO65748.1 - 4.1e-06 26.9 0.9 4.1e-06 26.9 0.6 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_AsnC-type PF13404.1 AEO65748.1 - 0.0013 18.2 1.0 0.0035 16.8 0.7 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_38 PF13936.1 AEO65748.1 - 0.0018 17.7 0.3 0.0018 17.7 0.2 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 AEO65748.1 - 0.031 13.7 0.1 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 Phage_int_SAM_4 PF13495.1 AEO65748.1 - 0.11 12.8 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_holin_1 PF04531.8 AEO65748.1 - 0.17 12.0 1.8 0.31 11.1 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage holin Fungal_trans PF04082.13 AEO65749.1 - 7.7e-23 80.6 0.1 1.7e-22 79.5 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO65749.1 - 2e-08 33.9 8.7 2e-08 33.9 6.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 AEO65750.1 - 1e-26 91.7 5.9 2.6e-07 30.2 0.2 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 AEO65750.1 - 0.00022 19.5 0.1 0.0066 14.6 0.0 2.6 3 0 0 3 3 3 1 Nucleoporin Nup120/160 eIF2A PF08662.6 AEO65750.1 - 0.015 15.0 0.1 23 4.6 0.0 3.7 2 2 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.6 AEO65750.1 - 0.043 12.7 0.0 0.85 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) RIC1 PF07064.8 AEO65751.1 - 1.9e-87 293.0 0.0 2.6e-87 292.5 0.0 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 AEO65751.1 - 5.4e-06 26.0 0.4 0.14 12.0 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat GST_N_3 PF13417.1 AEO65752.1 - 2.4e-21 75.7 0.0 4.3e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO65752.1 - 3.8e-15 55.6 0.0 7.3e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 AEO65752.1 - 6.4e-07 29.4 0.0 1.9e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain FAR1 PF03101.10 AEO65752.1 - 0.027 14.9 0.6 0.055 13.9 0.4 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain Glutaredoxin PF00462.19 AEO65752.1 - 0.06 13.3 0.0 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin GST_C_2 PF13410.1 AEO65753.1 - 6e-06 26.0 0.6 9e-06 25.4 0.4 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AEO65753.1 - 0.0048 16.8 0.0 0.0067 16.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CK_II_beta PF01214.13 AEO65754.1 - 1.1e-71 240.1 0.1 1.5e-71 239.7 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Nucleoplasmin PF03066.10 AEO65754.1 - 0.11 12.0 2.1 0.17 11.4 1.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin PAP2 PF01569.16 AEO65755.1 - 4.8e-19 68.3 5.1 4.8e-19 68.3 3.5 2.7 2 2 0 2 2 2 1 PAP2 superfamily Rhomboid PF01694.17 AEO65755.1 - 1.7 8.6 8.6 4.5 7.2 0.0 3.3 3 0 0 3 3 3 0 Rhomboid family Ribosomal_L2_C PF03947.13 AEO65756.1 - 1.2e-46 157.6 4.1 7.2e-46 155.2 2.8 2.2 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 AEO65756.1 - 1.4e-28 98.6 0.3 2.7e-28 97.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.18 AEO65757.1 - 9.3e-43 144.8 0.0 3.5e-42 142.9 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AEO65757.1 - 6.9e-32 109.8 0.0 1.3e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain ORC6 PF05460.8 AEO65759.1 - 0.034 13.2 2.0 0.038 13.1 1.4 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ion_trans PF00520.26 AEO65760.1 - 1.4e-109 363.9 72.3 1.9e-35 121.9 2.4 5.2 4 1 0 4 4 4 4 Ion transport protein DUF3366 PF11846.3 AEO65760.1 - 0.016 15.0 0.4 0.016 15.0 0.2 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3366) EF-hand_1 PF00036.27 AEO65760.1 - 0.045 13.0 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 EF hand JSRP PF15312.1 AEO65760.1 - 0.076 12.9 0.1 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein PHD PF00628.24 AEO65761.1 - 4e-08 32.8 9.7 7.8e-08 31.8 6.7 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 AEO65761.1 - 0.043 13.1 6.0 0.085 12.1 4.2 1.5 1 0 0 1 1 1 0 PHD-finger HMG_box PF00505.14 AEO65762.1 - 6.3e-10 39.1 2.8 1.4e-09 38.0 1.9 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AEO65762.1 - 0.0094 16.2 1.1 0.021 15.1 0.8 1.6 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 AEO65762.1 - 0.013 14.8 0.1 0.013 14.8 0.1 1.7 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 MMgT PF10270.4 AEO65763.1 - 1.2e-35 122.1 0.0 1.4e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter MutS_V PF00488.16 AEO65764.1 - 6.8e-51 172.9 0.0 1.1e-50 172.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AEO65764.1 - 2.1e-21 76.6 1.5 2.1e-21 76.6 1.1 1.9 2 0 0 2 2 2 1 MutS domain III AAA_29 PF13555.1 AEO65764.1 - 0.12 11.8 0.3 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain TPR_12 PF13424.1 AEO65765.1 - 3.1e-07 30.2 8.8 0.0014 18.5 1.9 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 AEO65765.1 - 6.1e-06 25.6 0.8 0.026 14.3 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 AEO65765.1 - 1.5e-05 24.5 5.5 0.029 14.2 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 AEO65765.1 - 0.0001 21.8 3.6 0.32 10.6 0.8 3.5 4 0 0 4 4 4 2 TPR repeat TPR_19 PF14559.1 AEO65765.1 - 0.00071 19.8 15.7 0.0025 18.1 0.3 4.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO65765.1 - 0.0019 18.8 19.1 0.004 17.7 3.2 4.5 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO65765.1 - 0.0026 17.3 0.0 0.25 11.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 AEO65765.1 - 0.0034 17.4 1.4 1.7 8.8 0.1 3.6 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 AEO65765.1 - 0.016 14.4 0.1 0.065 12.4 0.0 2.1 2 0 0 2 2 2 0 SHNi-TPR TPR_14 PF13428.1 AEO65765.1 - 0.018 15.6 17.9 2.1 9.1 0.0 6.5 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO65765.1 - 0.032 13.8 0.0 0.43 10.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 AEO65765.1 - 0.13 12.2 6.9 5.2 7.1 0.0 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF2681 PF10883.3 AEO65765.1 - 0.16 12.1 0.2 0.16 12.1 0.1 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF2681) TPR_9 PF13371.1 AEO65765.1 - 0.36 10.6 0.1 0.36 10.6 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 AEO65765.1 - 5.5 7.7 18.6 1.5 9.4 0.1 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO65765.1 - 10 6.8 10.0 89 3.8 0.0 5.5 6 1 0 6 6 6 0 Tetratricopeptide repeat RWD PF05773.17 AEO65766.1 - 3.6e-23 81.6 0.6 5.6e-23 80.9 0.4 1.3 1 0 0 1 1 1 1 RWD domain CPL PF08144.6 AEO65767.1 - 8.4e-19 67.8 0.0 3.2e-18 66.0 0.0 2.0 1 0 0 1 1 1 1 CPL (NUC119) domain CTI PF06934.6 AEO65767.1 - 0.05 11.8 0.1 0.075 11.2 0.0 1.1 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) RNA_pol_Rpb4 PF03874.11 AEO65768.1 - 6.2e-28 97.1 2.8 7.3e-28 96.9 2.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Spexin PF15171.1 AEO65768.1 - 0.091 12.7 0.1 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin WD40 PF00400.27 AEO65769.1 - 1.2e-13 50.3 1.0 0.88 9.5 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Imm42 PF15601.1 AEO65770.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 42 TRP PF06011.7 AEO65772.1 - 5.4e-93 311.9 23.7 2.1e-92 310.0 16.4 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 AEO65772.1 - 3.8e-32 111.2 0.2 5.7e-32 110.6 0.1 1.2 1 0 0 1 1 1 1 ML-like domain HATPase_c_3 PF13589.1 AEO65773.1 - 8.2e-12 44.9 0.0 2.6e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 AEO65773.1 - 5.6e-10 38.7 0.0 1.1e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 AEO65773.1 - 7.7e-10 38.4 0.1 1.5e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DMRL_synthase PF00885.14 AEO65774.1 - 1.1e-48 164.5 0.1 1.6e-29 102.4 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Nucleoplasmin PF03066.10 AEO65775.1 - 2.4 7.6 6.1 8.6 5.8 4.3 1.9 1 0 0 1 1 1 0 Nucleoplasmin Cation_efflux PF01545.16 AEO65776.1 - 5.6e-35 120.8 11.8 6.4e-35 120.6 8.2 1.0 1 0 0 1 1 1 1 Cation efflux family PI3_PI4_kinase PF00454.22 AEO65777.1 - 3.3e-40 138.0 0.0 9.2e-40 136.5 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 AEO65777.1 - 2.5e-22 78.9 0.0 5.1e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Sad1_UNC PF07738.8 AEO65777.1 - 0.27 11.0 0.0 0.55 10.0 0.0 1.4 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Proteasome PF00227.21 AEO65778.1 - 1.5e-29 102.6 0.1 3.5e-29 101.4 0.1 1.7 1 1 0 1 1 1 1 Proteasome subunit YTH PF04146.10 AEO65779.1 - 1e-56 190.3 0.0 1.4e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain RRM_6 PF14259.1 AEO65779.1 - 0.0052 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO65779.1 - 0.052 13.1 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO65779.1 - 0.22 11.4 0.1 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RVT_1 PF00078.22 AEO65780.1 - 0.00022 20.6 0.3 0.00026 20.4 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSP20 PF00011.16 AEO65781.1 - 9e-16 57.6 0.0 1.4e-11 44.1 0.0 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family LSM PF01423.17 AEO65782.1 - 1.3e-20 72.6 0.0 1.6e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AEO65782.1 - 0.00017 21.4 0.1 0.00019 21.2 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain AATase PF07247.7 AEO65785.1 - 9.3e-19 67.3 0.0 2.9e-18 65.6 0.0 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 AEO65785.1 - 0.002 17.0 0.1 0.07 11.9 0.0 2.2 2 0 0 2 2 2 2 Condensation domain WES_acyltransf PF03007.11 AEO65785.1 - 0.007 15.9 2.0 0.024 14.2 1.4 1.8 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Ribosomal_L9_N PF01281.14 AEO65786.1 - 7.6e-09 34.6 0.0 1.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 AEO65786.1 - 0.01 15.8 0.0 0.057 13.5 0.0 2.2 2 1 0 2 2 2 0 Ribosomal protein L9, C-terminal domain UCR_14kD PF02271.11 AEO65786.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit ATG11 PF10377.4 AEO65787.1 - 3.8e-42 143.2 0.1 3.8e-41 139.9 0.0 2.9 2 0 0 2 2 2 1 Autophagy-related protein 11 Tropomyosin PF00261.15 AEO65787.1 - 0.00014 21.0 8.6 0.00014 21.0 6.0 6.9 3 1 1 5 5 5 2 Tropomyosin Spectrin PF00435.16 AEO65787.1 - 0.0052 17.0 6.4 0.0052 17.0 4.5 9.4 5 3 5 11 11 11 2 Spectrin repeat MtrG PF04210.8 AEO65787.1 - 0.13 11.9 1.4 1.5 8.5 0.0 2.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G IncA PF04156.9 AEO65787.1 - 9.4 5.7 83.3 0.052 13.1 8.6 7.1 2 1 3 6 6 6 0 IncA protein Tropomyosin_1 PF12718.2 AEO65787.1 - 9.5 6.0 77.0 1.3 8.8 9.6 7.1 6 2 0 6 6 6 0 Tropomyosin like CENP-H PF05837.7 AEO65788.1 - 4.9e-20 71.6 0.2 1.1e-19 70.5 0.0 1.7 2 0 0 2 2 2 1 Centromere protein H (CENP-H) DUF2580 PF10824.3 AEO65788.1 - 0.029 14.6 2.0 0.04 14.2 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) AATF-Che1 PF13339.1 AEO65788.1 - 0.66 10.1 3.8 5.7 7.0 0.2 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor HMG_box PF00505.14 AEO65789.1 - 1.5e-25 89.2 1.1 2e-25 88.8 0.8 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AEO65789.1 - 8.1e-19 67.7 2.2 8.1e-19 67.7 1.5 1.5 1 1 1 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 AEO65789.1 - 0.00081 19.1 0.8 0.0015 18.3 0.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 AEO65789.1 - 0.023 14.8 0.2 0.086 13.0 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) DEADboxA PF12343.3 AEO65789.1 - 0.12 12.6 3.1 0.82 9.9 1.6 2.1 1 1 1 2 2 2 0 Cold shock protein DEAD box A PGM_PMM_I PF02878.11 AEO65791.1 - 1.2e-32 112.2 0.0 1.8e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 AEO65791.1 - 2.3e-24 85.5 0.0 4.1e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 AEO65791.1 - 4.3e-15 55.9 0.0 1e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 AEO65791.1 - 8.7e-10 38.4 0.0 1.9e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.19 AEO65792.1 - 9.2e-24 84.5 0.0 2.5e-23 83.1 0.0 1.6 1 1 1 2 2 2 1 Exonuclease GFO_IDH_MocA PF01408.17 AEO65793.1 - 5.8e-14 52.6 0.0 2.1e-13 50.8 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 AEO65793.1 - 1.5e-05 24.7 0.0 3.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain FhuF PF06276.7 AEO65793.1 - 0.06 13.3 0.0 2.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Ferric iron reductase FhuF-like transporter Oxysterol_BP PF01237.13 AEO65794.1 - 3.7e-91 305.2 0.0 4.3e-91 305.0 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein UCH PF00443.24 AEO65795.1 - 3.8e-40 137.6 0.0 5.6e-34 117.4 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO65795.1 - 9.8e-13 48.1 0.0 2.1e-08 33.9 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PIF1 PF05970.9 AEO65796.1 - 1.7e-15 56.8 0.0 1.8e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase tRNA-synt_2b PF00587.20 AEO65797.1 - 1.9e-34 118.7 0.0 2.7e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AEO65797.1 - 2.8e-06 27.1 0.0 4.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain CBF PF03914.12 AEO65798.1 - 2.8e-46 156.9 0.0 9.4e-46 155.2 0.0 2.0 2 0 0 2 2 2 1 CBF/Mak21 family APS_kinase PF01583.15 AEO65800.1 - 2e-70 235.4 0.0 2.9e-70 234.9 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase 4HBT PF03061.17 AEO65800.1 - 1.2e-08 34.9 0.0 2.4e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily AAA_33 PF13671.1 AEO65800.1 - 3e-07 30.4 0.0 8.3e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AEO65800.1 - 1.7e-05 25.6 0.0 2.9e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO65800.1 - 9e-05 22.7 0.0 0.00026 21.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 AEO65800.1 - 0.0011 18.2 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 AEO65800.1 - 0.042 13.3 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain V-ATPase_C PF03223.10 AEO65801.1 - 1e-115 386.6 0.0 1.1e-115 386.5 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C CENP-Q PF13094.1 AEO65801.1 - 0.13 12.3 1.0 0.26 11.3 0.7 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit F-box PF00646.28 AEO65803.1 - 7e-06 25.5 0.3 1.7e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 AEO65803.1 - 0.0014 18.3 0.6 0.0052 16.4 0.1 2.3 3 0 0 3 3 3 1 F-box-like Mod_r PF07200.8 AEO65805.1 - 2.4e-12 47.0 0.6 4.4e-12 46.1 0.4 1.4 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein SH3_9 PF14604.1 AEO65806.1 - 3.8e-31 106.4 2.9 8e-15 54.1 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 AEO65806.1 - 6.6e-26 89.4 4.8 3e-12 45.7 0.2 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 AEO65806.1 - 1.4e-16 59.6 0.0 6.4e-08 31.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 AEO65806.1 - 3.5e-12 46.3 0.0 5.4e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CYSTM PF12734.2 AEO65807.1 - 8 6.6 89.8 0.21 11.6 36.1 5.0 2 1 1 3 3 3 0 Cysteine-rich TM module stress tolerance Glutaredoxin PF00462.19 AEO65808.1 - 3.1e-17 62.3 0.0 1e-15 57.4 0.0 2.6 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 AEO65808.1 - 3.5e-16 58.7 0.0 8.3e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AEO65808.1 - 0.0001 22.5 0.1 0.039 14.1 0.0 3.3 1 1 2 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AEO65808.1 - 0.0024 17.9 0.0 1.4 9.0 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.1 AEO65808.1 - 0.005 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin domain Phosducin PF02114.11 AEO65808.1 - 0.035 12.8 0.0 0.052 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosducin Fungal_trans PF04082.13 AEO65809.1 - 5e-21 74.7 1.0 7.7e-21 74.1 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Alpha-amylase PF00128.19 AEO65810.1 - 9.5e-62 209.1 0.0 1.3e-61 208.7 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 AEO65810.1 - 1.5e-32 111.5 1.5 2.6e-31 107.5 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) CBM_20 PF00686.14 AEO65810.1 - 1.1e-29 101.8 0.4 2.5e-29 100.7 0.3 1.6 1 0 0 1 1 1 1 Starch binding domain F-box-like PF12937.2 AEO65812.1 - 0.0018 17.9 0.1 0.0043 16.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO65812.1 - 0.0019 17.8 0.0 0.005 16.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain Dynamin_M PF01031.15 AEO65813.1 - 1.4e-114 381.9 0.0 3.8e-114 380.4 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 AEO65813.1 - 1.8e-56 190.5 0.2 5.6e-56 188.9 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 AEO65813.1 - 2.8e-31 107.2 2.8 2.8e-31 107.2 1.9 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 AEO65813.1 - 0.00062 19.7 0.2 0.0034 17.3 0.1 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 AEO65813.1 - 0.02 15.3 0.0 0.056 13.9 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein MFS_1 PF07690.11 AEO65814.1 - 3.7e-28 98.2 95.9 3.4e-23 81.9 40.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO65814.1 - 1.8e-07 29.9 32.7 3.3e-06 25.7 11.1 2.2 1 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 AEO65814.1 - 0.001 18.8 0.0 0.0047 16.6 0.0 2.2 1 0 0 1 1 1 1 MFS_1 like family LIM PF00412.17 AEO65815.1 - 2.9e-26 91.3 21.4 6.6e-09 35.7 0.8 3.4 3 0 0 3 3 3 3 LIM domain DUF2321 PF10083.4 AEO65815.1 - 0.053 13.0 0.3 0.053 13.0 0.2 2.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-dskA_traR PF01258.12 AEO65815.1 - 0.074 12.8 0.3 0.074 12.8 0.2 4.9 6 0 0 6 6 6 0 Prokaryotic dksA/traR C4-type zinc finger DUF678 PF05077.7 AEO65815.1 - 1.1 9.3 5.0 8.5 6.4 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF678) Nudix_N_2 PF14803.1 AEO65815.1 - 4.4 7.0 15.9 1.4 8.6 0.5 4.9 5 0 0 5 5 5 0 Nudix N-terminal Rad60-SLD PF11976.3 AEO65816.1 - 2.1e-19 68.9 0.2 2.5e-19 68.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 AEO65816.1 - 1.5e-08 33.9 0.1 1.8e-08 33.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family HH_signal PF01085.13 AEO65816.1 - 0.0062 16.1 0.0 0.0064 16.0 0.0 1.0 1 0 0 1 1 1 1 Hedgehog amino-terminal signalling domain DUF1903 PF08991.5 AEO65817.1 - 1.5e-26 92.3 5.8 1.7e-26 92.1 4.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) zf-C4 PF00105.13 AEO65817.1 - 0.029 14.5 1.2 0.029 14.5 0.8 1.8 1 1 1 2 2 2 0 Zinc finger, C4 type (two domains) Cmc1 PF08583.5 AEO65817.1 - 0.034 13.9 1.7 0.034 13.9 1.2 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 AEO65817.1 - 0.11 12.4 7.3 0.084 12.8 4.1 1.6 2 0 0 2 2 2 0 CHCH domain Nup84_Nup100 PF04121.8 AEO65818.1 - 2.7e-62 210.5 0.0 5.3e-61 206.2 0.0 2.6 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 FMN_dh PF01070.13 AEO65819.1 - 1.8e-96 323.1 0.8 8e-96 320.9 0.5 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 AEO65819.1 - 0.00013 21.0 0.7 0.0014 17.6 0.2 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 AEO65819.1 - 0.00017 20.6 0.1 0.00025 20.0 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 AEO65819.1 - 0.0006 19.0 0.7 0.00089 18.5 0.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 AEO65819.1 - 0.0036 16.4 0.4 0.026 13.6 0.1 2.0 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG IGPS PF00218.16 AEO65819.1 - 0.01 14.8 0.1 0.022 13.7 0.1 1.5 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase His_biosynth PF00977.16 AEO65819.1 - 0.037 13.2 0.1 0.15 11.3 0.0 1.8 1 1 1 2 2 2 0 Histidine biosynthesis protein Pro_isomerase PF00160.16 AEO65820.1 - 1.5e-50 171.4 0.1 5.8e-50 169.5 0.1 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 AEO65820.1 - 9.1e-16 57.0 0.6 1e-07 31.5 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat DAHP_synth_1 PF00793.15 AEO65821.1 - 6.5e-98 326.7 0.0 7.8e-98 326.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Mu-like_Pro PF10123.4 AEO65821.1 - 0.048 13.1 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein Cytochrom_C1 PF02167.10 AEO65822.1 - 1.6e-82 276.3 0.0 2e-82 276.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 AEO65822.1 - 0.0066 16.5 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III HhH-GPD PF00730.20 AEO65823.1 - 1.1e-09 38.4 0.0 1.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein CVNH PF08881.5 AEO65824.1 - 3.6e-08 33.5 0.1 5.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 CVNH domain adh_short PF00106.20 AEO65825.1 - 1.2e-24 87.1 0.0 1.5e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO65825.1 - 1.2e-23 84.1 0.0 1.6e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO65825.1 - 5e-09 36.0 0.0 6.7e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 AEO65825.1 - 0.0057 16.4 0.1 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ABC_tran PF00005.22 AEO65826.1 - 2.8e-49 166.9 0.0 2.8e-30 105.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AEO65826.1 - 1.5e-22 80.2 30.4 6.3e-17 61.8 13.2 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 AEO65826.1 - 6.4e-09 35.3 0.0 0.0086 15.3 0.0 4.1 4 1 1 5 5 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 AEO65826.1 - 3.3e-07 29.9 0.3 0.12 11.7 0.0 3.5 3 0 0 3 3 3 3 AAA domain AAA_29 PF13555.1 AEO65826.1 - 8.4e-06 25.2 1.0 0.057 12.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 AEO65826.1 - 1e-05 25.6 0.7 0.15 12.0 0.2 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 AEO65826.1 - 1.9e-05 25.0 0.2 0.017 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AEO65826.1 - 6.8e-05 21.9 0.0 0.017 14.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_21 PF13304.1 AEO65826.1 - 9.4e-05 22.5 0.1 14 5.5 0.0 4.0 3 1 1 4 4 4 0 AAA domain AAA_10 PF12846.2 AEO65826.1 - 0.00023 20.7 0.2 4.1 6.7 0.0 3.3 3 0 0 3 3 3 1 AAA-like domain AAA_22 PF13401.1 AEO65826.1 - 0.00025 21.1 0.6 2.1 8.5 0.1 3.8 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 AEO65826.1 - 0.00033 20.5 4.6 0.022 14.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF258 PF03193.11 AEO65826.1 - 0.00094 18.3 0.1 0.34 10.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 AEO65826.1 - 0.00097 19.0 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 AEO65826.1 - 0.0013 19.5 0.1 0.4 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 AEO65826.1 - 0.0014 17.4 0.5 0.17 10.6 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_18 PF13238.1 AEO65826.1 - 0.013 15.8 0.2 6.2 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 AEO65826.1 - 0.013 15.9 0.1 9.8 6.7 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 AEO65826.1 - 0.027 14.1 1.2 2.8 7.5 0.4 2.7 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.1 AEO65826.1 - 0.04 13.8 0.0 4.5 7.2 0.0 3.4 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 AEO65826.1 - 0.059 12.4 0.2 11 5.0 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.21 AEO65826.1 - 0.068 12.6 0.1 11 5.4 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 AEO65826.1 - 0.1 12.0 0.0 6.4 6.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 AEO65826.1 - 0.11 11.5 0.1 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 AEO65826.1 - 0.17 10.8 1.5 0.81 8.5 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 AEO65826.1 - 0.3 9.9 1.1 3.3 6.4 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain DUF1673 PF07895.6 AEO65826.1 - 1.9 7.9 11.1 19 4.6 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) zf-B_box PF00643.19 AEO65827.1 - 0.0046 16.8 6.7 0.0082 16.0 4.6 1.4 1 0 0 1 1 1 1 B-box zinc finger Myb_DNA-bind_6 PF13921.1 AEO65828.1 - 1.5e-05 25.0 0.3 2.6e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO65828.1 - 0.00072 19.5 0.5 0.0015 18.5 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cut8_N PF14482.1 AEO65828.1 - 0.029 14.3 2.3 0.029 14.3 1.6 2.7 2 0 0 2 2 2 0 Cut8 proteasome-binding domain PBP1_TM PF14812.1 AEO65828.1 - 0.52 10.6 7.2 0.22 11.8 3.1 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal p450 PF00067.17 AEO65829.1 - 2.7e-74 250.3 0.0 3.3e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Prenyltrans_2 PF13249.1 AEO65829.1 - 0.052 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Prenyltransferase-like Acetyltransf_1 PF00583.19 AEO65830.1 - 4.6e-11 42.5 0.0 7.4e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO65830.1 - 4.9e-08 33.0 0.1 1.1e-07 31.9 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO65830.1 - 9e-07 29.0 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AEO65830.1 - 0.004 17.1 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AEO65830.1 - 0.012 15.8 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AEO65830.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 AEO65830.1 - 0.038 13.8 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO65830.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Ribonuc_L-PSP PF01042.16 AEO65832.1 - 1.8e-41 140.6 0.0 2e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP PMT PF02366.13 AEO65833.1 - 6.1e-81 271.3 17.3 6.1e-81 271.3 12.0 1.5 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 AEO65833.1 - 5.3e-19 68.4 0.5 4.4e-18 65.4 0.2 2.1 1 1 1 2 2 2 2 MIR domain zf-C2H2 PF00096.21 AEO65834.1 - 0.016 15.5 2.6 0.016 15.5 1.8 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO65834.1 - 0.9 10.0 18.7 0.099 13.0 1.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Helicase_C PF00271.26 AEO65838.1 - 6.5e-21 73.9 0.2 3.4e-20 71.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 AEO65838.1 - 1.4e-20 73.4 0.0 3.4e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 AEO65838.1 - 6.7e-20 71.6 0.0 1.3e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AEO65838.1 - 0.00021 21.4 0.0 0.00088 19.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_10 PF12846.2 AEO65838.1 - 0.057 12.8 0.2 3.7 6.8 0.0 3.2 2 2 1 3 3 3 0 AAA-like domain PhoH PF02562.11 AEO65838.1 - 0.12 11.6 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein LRR_4 PF12799.2 AEO65839.1 - 3.1e-11 42.6 5.6 9.9e-07 28.2 0.2 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) TAP_C PF03943.8 AEO65839.1 - 6.5e-11 41.4 0.0 1.2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain LRR_8 PF13855.1 AEO65839.1 - 0.00016 21.3 0.1 0.00038 20.1 0.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 AEO65839.1 - 0.00033 20.2 0.4 0.033 14.1 0.1 3.3 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_7 PF13504.1 AEO65839.1 - 0.0028 17.5 1.1 0.17 12.1 0.2 3.1 2 0 0 2 2 2 1 Leucine rich repeat NTF2 PF02136.15 AEO65839.1 - 0.093 13.1 0.0 0.25 11.7 0.0 1.7 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Herpes_gE PF02480.11 AEO65840.1 - 0.00014 20.3 0.1 0.00023 19.5 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Kelch_4 PF13418.1 AEO65840.1 - 0.0022 17.7 6.8 0.11 12.2 0.0 3.7 4 1 0 4 4 4 2 Galactose oxidase, central domain Alpha_GJ PF03229.8 AEO65840.1 - 0.0076 16.5 10.8 0.0076 16.5 7.5 3.4 5 0 0 5 5 5 1 Alphavirus glycoprotein J Pex14_N PF04695.8 AEO65840.1 - 2.7 8.0 15.0 0.88 9.6 1.4 3.7 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HLH PF00010.21 AEO65841.1 - 1.2e-18 66.5 0.7 6.6e-18 64.1 0.0 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain MSC PF09402.5 AEO65842.1 - 2.8e-109 364.8 0.0 3.8e-109 364.4 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 AEO65842.1 - 6.3e-18 64.0 0.1 1.7e-17 62.6 0.0 1.8 2 0 0 2 2 2 1 HeH/LEM domain Thymopoietin PF08198.6 AEO65842.1 - 0.0069 15.8 0.1 0.018 14.5 0.0 1.7 1 0 0 1 1 1 1 Thymopoietin protein DUF3350 PF11830.3 AEO65842.1 - 0.03 14.3 1.3 4.4 7.4 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) HisG PF01634.13 AEO65843.1 - 2.1e-48 163.9 0.6 3.2e-46 156.8 0.2 2.5 2 1 0 2 2 2 1 ATP phosphoribosyltransferase HisG_C PF08029.6 AEO65843.1 - 1e-28 99.0 0.5 1.9e-28 98.2 0.3 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain MFS_2 PF13347.1 AEO65844.1 - 4.4e-10 38.5 1.1 4.4e-10 38.5 0.7 3.2 3 1 1 4 4 4 2 MFS/sugar transport protein Nuc_H_symport PF03825.11 AEO65844.1 - 0.012 14.4 3.5 0.035 12.8 1.0 2.4 2 0 0 2 2 2 0 Nucleoside H+ symporter MFS_1_like PF12832.2 AEO65844.1 - 0.24 11.2 3.7 0.39 10.5 0.0 3.1 3 0 0 3 3 3 0 MFS_1 like family Abi PF02517.11 AEO65844.1 - 5.7 7.1 8.4 27 4.9 0.9 3.1 2 2 0 2 2 2 0 CAAX protease self-immunity Sel1 PF08238.7 AEO65845.1 - 9e-37 124.6 30.8 5e-05 23.7 0.1 7.5 7 0 0 7 7 7 7 Sel1 repeat Na_trans_assoc PF06512.8 AEO65845.1 - 0.5 10.3 4.5 0.85 9.5 3.1 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Chitin_synth_2 PF03142.10 AEO65846.1 - 2.5e-295 979.9 0.2 3.7e-295 979.3 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 AEO65846.1 - 1.6e-18 67.0 4.1 8e-18 64.8 2.9 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AEO65846.1 - 7.1e-15 55.4 0.1 1.8e-13 50.8 0.0 2.5 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 AEO65846.1 - 9.3e-13 47.7 0.0 1.7e-10 40.5 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 AEO65846.1 - 0.00012 21.4 0.0 0.00062 19.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 AEO65846.1 - 0.038 13.6 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 WD40 PF00400.27 AEO65847.1 - 9.9e-08 31.5 3.6 4.7e-06 26.2 0.4 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF2415 PF10313.4 AEO65847.1 - 0.032 13.8 0.0 0.54 9.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) TFIIIC_delta PF12657.2 AEO65847.1 - 0.088 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Glyco_hydro_17 PF00332.13 AEO65848.1 - 0.1 11.6 0.6 0.2 10.6 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 RNB PF00773.14 AEO65849.1 - 1.1e-67 228.6 0.0 1.8e-67 227.9 0.0 1.4 1 0 0 1 1 1 1 RNB domain CRIC_ras_sig PF10534.4 AEO65849.1 - 0.014 15.4 0.0 0.057 13.4 0.0 2.1 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras Sec10 PF07393.6 AEO65850.1 - 2.9e-229 762.9 1.1 3.4e-229 762.6 0.8 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Prenyltransf PF01255.14 AEO65851.1 - 1.1e-08 34.4 0.1 1.5e-07 30.8 0.0 2.0 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase Met_10 PF02475.11 AEO65852.1 - 8.3e-74 247.5 0.0 1.1e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein DUF1752 PF08550.5 AEO65854.1 - 2.4e-08 33.4 1.6 4.5e-08 32.5 1.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) PBP1_TM PF14812.1 AEO65854.1 - 0.19 12.0 13.1 1.2 9.4 1.6 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spt5_N PF11942.3 AEO65854.1 - 3.9 8.1 14.1 1.4 9.5 0.4 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Proteasome PF00227.21 AEO65855.1 - 2.1e-48 164.1 0.2 2.5e-48 163.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 AEO65855.1 - 0.0072 15.5 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF554) Peptidase_M22 PF00814.20 AEO65856.1 - 4.6e-40 137.8 0.0 1.1e-21 77.6 0.2 3.7 2 1 0 2 2 2 2 Glycoprotease family UPF0016 PF01169.14 AEO65856.1 - 0.67 10.1 1.8 0.59 10.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 Glyco_transf_34 PF05637.7 AEO65857.1 - 2.5e-66 223.5 0.5 3.3e-66 223.2 0.3 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_hydro_16 PF00722.16 AEO65858.1 - 4.6e-08 32.5 0.1 2.7e-07 30.0 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Adeno_shaft PF00608.12 AEO65858.1 - 0.041 13.4 0.6 0.094 12.3 0.4 1.7 1 0 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) AIP3 PF03915.8 AEO65859.1 - 0.0002 20.3 4.5 0.0002 20.3 3.1 2.2 1 1 2 3 3 3 1 Actin interacting protein 3 AAA_13 PF13166.1 AEO65859.1 - 0.0029 16.1 5.0 0.004 15.6 3.5 1.1 1 0 0 1 1 1 1 AAA domain TIP120 PF08623.5 AEO65859.1 - 0.0087 15.6 1.5 0.016 14.8 1.0 1.5 1 0 0 1 1 1 1 TATA-binding protein interacting (TIP20) Mnd1 PF03962.10 AEO65859.1 - 0.0091 15.6 15.2 0.02 14.5 5.2 2.8 1 1 1 2 2 2 1 Mnd1 family DUF3584 PF12128.3 AEO65859.1 - 0.01 13.2 12.3 0.013 12.8 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LemA PF04011.7 AEO65859.1 - 0.011 14.9 2.6 0.022 13.8 1.8 1.6 1 0 0 1 1 1 0 LemA family DUF904 PF06005.7 AEO65859.1 - 0.018 15.3 14.6 0.032 14.5 1.2 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF904) NPV_P10 PF05531.7 AEO65859.1 - 0.023 14.9 8.3 0.093 12.9 2.3 3.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Sugarporin_N PF11471.3 AEO65859.1 - 0.024 14.2 2.3 0.024 14.2 1.6 2.9 2 1 1 3 3 2 0 Maltoporin periplasmic N-terminal extension Spc7 PF08317.6 AEO65859.1 - 0.024 13.3 12.8 0.007 15.0 4.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein MCPsignal PF00015.16 AEO65859.1 - 0.037 13.5 6.7 0.06 12.8 4.6 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2935 PF11155.3 AEO65859.1 - 0.05 13.7 1.8 1.1 9.3 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) ApoLp-III PF07464.6 AEO65859.1 - 0.076 13.0 7.8 0.11 12.4 3.8 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) APG6 PF04111.7 AEO65859.1 - 0.086 11.8 14.0 0.03 13.3 3.7 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 FUSC PF04632.7 AEO65859.1 - 0.096 11.0 17.8 0.17 10.3 12.3 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tropomyosin_1 PF12718.2 AEO65859.1 - 0.11 12.3 14.7 1 9.2 1.3 2.4 1 1 1 2 2 2 0 Tropomyosin like Prefoldin_2 PF01920.15 AEO65859.1 - 0.17 11.6 10.8 1.5 8.6 0.3 3.5 2 1 1 3 3 3 0 Prefoldin subunit DUF1664 PF07889.7 AEO65859.1 - 0.18 11.5 4.6 0.23 11.2 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 AEO65859.1 - 0.27 11.3 7.8 4.5 7.3 3.3 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2937 PF11157.3 AEO65859.1 - 0.28 10.5 12.4 0.58 9.4 3.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) CCDC-167 PF15188.1 AEO65859.1 - 0.31 11.0 6.4 0.25 11.3 1.7 2.5 3 0 0 3 3 2 0 Coiled-coil domain-containing protein 167 Baculo_PEP_C PF04513.7 AEO65859.1 - 0.38 10.5 10.1 0.78 9.5 3.6 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lectin_N PF03954.9 AEO65859.1 - 0.49 9.7 5.9 6.6 6.1 0.4 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Reo_sigmaC PF04582.7 AEO65859.1 - 0.53 9.4 4.9 0.52 9.4 2.2 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein GAS PF13851.1 AEO65859.1 - 0.58 9.3 10.4 4.7 6.3 2.9 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FH2 PF02181.18 AEO65859.1 - 0.58 8.9 4.9 0.26 10.1 1.2 1.9 1 1 1 2 2 2 0 Formin Homology 2 Domain Fmp27_WPPW PF10359.4 AEO65859.1 - 0.73 8.1 5.7 0.24 9.7 1.8 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Sec34 PF04136.10 AEO65859.1 - 0.99 9.0 4.9 8.9 5.9 0.6 2.3 1 1 1 2 2 2 0 Sec34-like family IFT57 PF10498.4 AEO65859.1 - 1 8.0 8.7 0.29 9.8 2.6 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 HR1 PF02185.11 AEO65859.1 - 1.2 8.9 11.4 2 8.1 0.2 3.8 2 2 1 3 3 3 0 Hr1 repeat Hemerythrin PF01814.18 AEO65859.1 - 1.2 9.2 9.7 2 8.5 3.3 2.7 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain DUF148 PF02520.12 AEO65859.1 - 1.4 8.7 4.8 0.98 9.2 1.2 2.3 2 1 1 3 3 2 0 Domain of unknown function DUF148 SlyX PF04102.7 AEO65859.1 - 2.2 8.7 15.8 6.9 7.1 0.1 4.6 2 1 1 3 3 3 0 SlyX DUF3450 PF11932.3 AEO65859.1 - 2.2 7.4 13.5 2.5 7.3 8.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HrpB7 PF09486.5 AEO65859.1 - 2.5 7.9 24.6 4.1 7.3 8.6 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) TMF_DNA_bd PF12329.3 AEO65859.1 - 2.6 7.9 13.8 85 3.0 6.0 3.6 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.6 AEO65859.1 - 2.7 7.7 11.7 2.4 7.8 0.4 3.0 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 CorA PF01544.13 AEO65859.1 - 2.8 6.9 8.3 1.2 8.0 3.6 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Striatin PF08232.7 AEO65859.1 - 2.9 8.2 11.6 0.53 10.6 1.1 2.9 1 1 2 3 3 3 0 Striatin family Syntaxin-6_N PF09177.6 AEO65859.1 - 3 8.3 8.4 1.4 9.4 1.3 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.7 AEO65859.1 - 3.7 7.3 17.2 52 3.5 11.4 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CDC37_N PF03234.9 AEO65859.1 - 4.9 7.4 7.2 14 5.9 0.2 2.7 1 1 2 3 3 3 0 Cdc37 N terminal kinase binding PspB PF06667.7 AEO65859.1 - 6.3 6.8 5.8 15 5.6 0.3 2.9 1 1 1 2 2 2 0 Phage shock protein B Spectrin PF00435.16 AEO65859.1 - 6.6 7.0 16.2 1.3 9.3 2.8 3.2 1 1 2 3 3 3 0 Spectrin repeat Kinetocho_Slk19 PF12709.2 AEO65859.1 - 6.7 6.8 6.7 20 5.3 0.3 3.5 2 1 0 3 3 3 0 Central kinetochore-associated DUF1515 PF07439.6 AEO65859.1 - 7 6.5 7.4 4.2 7.2 0.8 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) COG2 PF06148.6 AEO65859.1 - 8.2 6.3 10.0 26 4.6 4.0 3.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Abhydrolase_2 PF02230.11 AEO65860.1 - 1.6e-24 86.5 0.0 5.9e-17 61.8 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 AEO65860.1 - 8.2e-07 29.1 0.6 2.8e-06 27.3 0.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO65860.1 - 1.9e-05 24.4 0.1 3.2e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO65860.1 - 2.6e-05 23.5 0.0 0.00011 21.4 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 AEO65860.1 - 7.2e-05 22.3 0.0 0.00034 20.1 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 AEO65860.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 AEO65860.1 - 0.11 11.2 0.1 0.18 10.4 0.1 1.3 1 0 0 1 1 1 0 Carboxylesterase family ABM PF03992.11 AEO65861.1 - 4.2e-06 26.6 0.2 0.0002 21.3 0.0 2.5 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF3500 PF12006.3 AEO65862.1 - 8.5e-103 343.5 0.0 1e-102 343.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Med16 PF11635.3 AEO65863.1 - 7e-114 381.4 0.0 9.6e-114 380.9 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 TFIIIC_delta PF12657.2 AEO65863.1 - 0.007 16.0 1.1 0.48 10.1 0.0 3.4 4 0 0 4 4 4 1 Transcription factor IIIC subunit delta N-term SIR2 PF02146.12 AEO65864.1 - 4.6e-26 91.6 0.0 1.3e-25 90.1 0.0 1.7 1 1 0 1 1 1 1 Sir2 family SNF2_N PF00176.18 AEO65865.1 - 9.9e-65 218.2 0.0 1.7e-64 217.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 AEO65865.1 - 3.5e-29 100.2 3.7 1.4e-16 59.9 0.3 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 AEO65865.1 - 7.6e-15 54.5 0.0 2.4e-14 52.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain POR PF01558.13 AEO65865.1 - 0.023 14.6 0.1 0.26 11.1 0.0 2.4 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase ABC_tran PF00005.22 AEO65866.1 - 3.5e-34 118.0 0.0 7.1e-16 58.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AEO65866.1 - 3.1e-14 53.6 12.5 2.6e-05 24.3 0.0 4.7 3 2 2 5 5 5 4 AAA domain SMC_N PF02463.14 AEO65866.1 - 9.7e-10 38.0 2.1 0.0048 16.1 0.0 3.5 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 AEO65866.1 - 2e-07 30.3 0.1 0.89 8.5 0.0 4.5 5 0 0 5 5 5 2 AAA ATPase domain AAA_17 PF13207.1 AEO65866.1 - 1.3e-06 29.2 0.2 0.047 14.5 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 AEO65866.1 - 1.5e-06 28.4 0.1 0.006 16.7 0.1 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 AEO65866.1 - 7.2e-06 26.3 0.1 0.2 11.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 AEO65866.1 - 8.9e-06 25.8 0.0 0.0097 16.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 AEO65866.1 - 0.00021 20.5 0.0 0.41 9.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 AEO65866.1 - 0.00046 19.9 2.0 0.042 13.5 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 AEO65866.1 - 0.00061 20.1 0.1 0.1 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 AEO65866.1 - 0.00066 19.1 2.2 0.039 13.3 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 AEO65866.1 - 0.00067 19.8 0.1 0.36 11.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase VirE PF05272.6 AEO65866.1 - 0.0012 18.3 0.1 1.8 7.9 0.0 2.7 2 0 0 2 2 2 2 Virulence-associated protein E AAA_16 PF13191.1 AEO65866.1 - 0.0013 18.7 0.8 0.28 11.1 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain UPF0079 PF02367.12 AEO65866.1 - 0.0015 18.1 0.3 0.016 14.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 AEO65866.1 - 0.0016 18.1 1.3 0.3 10.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Thymidylate_kin PF02223.12 AEO65866.1 - 0.003 16.9 0.3 1.2 8.4 0.1 2.9 3 0 0 3 3 3 1 Thymidylate kinase AAA_28 PF13521.1 AEO65866.1 - 0.0036 17.2 0.2 0.32 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AEO65866.1 - 0.0039 17.0 0.4 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AEO65866.1 - 0.0045 16.4 1.9 1.8 8.1 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 AEO65866.1 - 0.012 16.1 0.1 1.2 9.6 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_5 PF07728.9 AEO65866.1 - 0.012 15.3 0.3 1.3 8.7 0.0 3.0 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.1 AEO65866.1 - 0.015 13.7 0.0 0.015 13.7 0.0 2.1 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.10 AEO65866.1 - 0.015 13.9 0.1 0.13 10.8 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 AEO65866.1 - 0.016 14.0 0.0 0.95 8.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 AEO65866.1 - 0.021 14.1 0.8 4.2 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 AEO65866.1 - 0.078 12.8 2.2 11 5.9 0.0 3.5 2 2 1 3 3 3 0 AAA domain SbcCD_C PF13558.1 AEO65866.1 - 0.1 12.4 0.1 7.1 6.6 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 AEO65866.1 - 0.13 11.8 0.2 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 AEO65866.1 - 0.19 10.8 0.5 0.49 9.4 0.1 1.9 2 0 0 2 2 1 0 KaiC NTPase_1 PF03266.10 AEO65866.1 - 0.2 11.3 2.5 6.7 6.3 0.1 2.6 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 AEO65866.1 - 0.22 11.0 0.1 0.22 11.0 0.1 2.9 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 AEO65866.1 - 0.33 9.8 1.9 2.1 7.1 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_24 PF13479.1 AEO65866.1 - 0.84 9.1 3.0 2.8 7.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain FF PF01846.14 AEO65867.1 - 4e-51 170.7 12.9 2.9e-14 52.7 0.0 7.3 7 1 0 7 7 7 6 FF domain WW PF00397.21 AEO65867.1 - 4.7e-19 67.9 16.7 2.3e-10 40.1 3.3 2.5 2 0 0 2 2 2 2 WW domain Trs65 PF12735.2 AEO65868.1 - 4.5e-87 292.2 0.0 6.9e-87 291.6 0.0 1.3 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 SLD3 PF08639.5 AEO65869.1 - 4.1e-131 438.0 0.7 4.1e-131 438.0 0.5 2.1 2 0 0 2 2 2 1 DNA replication regulator SLD3 Pkinase PF00069.20 AEO65870.1 - 2.5e-68 230.0 0.0 7.9e-68 228.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO65870.1 - 2.1e-37 128.6 0.0 3.6e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO65870.1 - 1.1e-06 27.8 0.0 2.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO65870.1 - 0.022 14.4 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AEO65870.1 - 0.091 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 MSA-2c PF12238.3 AEO65870.1 - 5.1 6.6 9.2 35 3.9 0.1 2.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c Homeobox PF00046.24 AEO65871.1 - 2.9e-15 55.6 1.7 5.7e-15 54.6 1.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 AEO65871.1 - 0.00033 20.2 0.1 0.00077 19.1 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain HAD_2 PF13419.1 AEO65872.1 - 4.1e-16 59.6 0.0 5.7e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO65872.1 - 7.4e-10 38.4 0.1 1.5e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 AEO65872.1 - 5.1e-08 33.5 0.0 6e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AEO65872.1 - 0.062 13.4 0.0 0.09 12.9 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase GN3L_Grn1 PF08701.6 AEO65873.1 - 3e-25 87.9 17.3 6.3e-25 86.8 12.0 1.5 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 AEO65873.1 - 6.4e-20 71.2 0.3 2.3e-13 50.0 0.1 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 AEO65873.1 - 2.4e-07 30.7 3.3 0.0052 16.6 0.1 3.7 3 1 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 AEO65873.1 - 9.1e-07 28.4 0.0 0.011 15.1 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 AEO65873.1 - 0.00099 18.4 0.1 0.022 14.0 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 AEO65873.1 - 0.0025 17.0 0.2 0.0044 16.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 AEO65873.1 - 0.012 16.1 0.1 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein ArgK PF03308.11 AEO65873.1 - 0.11 11.2 0.0 0.11 11.2 0.0 1.9 2 0 0 2 2 2 0 ArgK protein DUF3439 PF11921.3 AEO65873.1 - 0.12 12.1 5.1 0.27 10.9 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) AAA_16 PF13191.1 AEO65873.1 - 0.29 11.1 5.3 0.48 10.3 0.1 3.0 2 1 0 2 2 2 0 AAA ATPase domain DUF1675 PF07897.6 AEO65873.1 - 0.3 10.9 5.0 0.54 10.0 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) RNB PF00773.14 AEO65874.1 - 1.3e-94 317.1 0.0 1.9e-94 316.6 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 AEO65874.1 - 1.2e-09 38.3 2.0 2.2e-09 37.5 0.1 2.4 2 1 0 2 2 2 1 PIN domain OB_RNB PF08206.6 AEO65874.1 - 0.11 11.9 0.0 0.45 10.0 0.0 2.1 1 0 0 1 1 1 0 Ribonuclease B OB domain CRC_subunit PF08624.5 AEO65877.1 - 1.4e-53 180.4 0.0 2.1e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CBFD_NFYB_HMF PF00808.18 AEO65878.1 - 2.4e-09 37.1 0.1 4.4e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AEO65878.1 - 9.4e-05 22.4 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Mito_fiss_reg PF05308.6 AEO65878.1 - 5.5 6.2 12.4 0.76 9.0 4.1 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator PBP1_TM PF14812.1 AEO65878.1 - 6.2 7.1 12.3 1.7 8.9 3.0 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal tRNA_int_end_N2 PF12928.2 AEO65879.1 - 0.17 11.3 0.3 0.3 10.5 0.2 1.3 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term PIRT PF15099.1 AEO65879.1 - 0.19 10.9 0.3 0.34 10.1 0.2 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Aldedh PF00171.17 AEO65880.1 - 4.1e-109 364.9 0.0 5.3e-109 364.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HLH PF00010.21 AEO65881.1 - 1.3e-13 50.3 1.3 3.9e-13 48.8 0.3 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PhoD PF09423.5 AEO65883.1 - 4.2e-08 32.1 0.0 1.3e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Rhomboid PF01694.17 AEO65884.1 - 1.7e-23 83.3 7.3 1.7e-23 83.3 5.0 1.5 2 0 0 2 2 2 1 Rhomboid family 7TM-7TMR_HD PF07698.6 AEO65884.1 - 0.22 10.9 8.1 0.64 9.4 0.1 2.5 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Med2 PF11214.3 AEO65884.1 - 0.31 11.1 2.9 0.52 10.3 2.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 DinB_2 PF12867.2 AEO65885.1 - 0.0087 16.4 0.8 0.036 14.4 0.2 2.0 2 0 0 2 2 2 1 DinB superfamily Dicty_REP PF05086.7 AEO65885.1 - 0.24 9.1 0.1 0.29 8.8 0.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF607 PF04678.8 AEO65887.1 - 2.5 8.0 4.8 1.2 9.0 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF607 IU_nuc_hydro PF01156.14 AEO65888.1 - 6.7e-59 199.6 0.0 2.8e-47 161.4 0.0 2.1 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase LSM PF01423.17 AEO65889.1 - 5.5e-16 57.8 0.1 6.9e-16 57.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain HpcH_HpaI PF03328.9 AEO65890.1 - 2.6e-34 118.0 0.0 3.1e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 AEO65890.1 - 0.0063 15.7 0.7 9.9 5.2 0.0 3.4 3 1 1 4 4 4 3 Phosphoenolpyruvate phosphomutase DUF2156 PF09924.4 AEO65890.1 - 0.0073 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) DUF836 PF05768.9 AEO65891.1 - 3e-14 53.0 0.0 3.5e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 AEO65891.1 - 0.00064 19.6 0.1 0.0016 18.3 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_2 PF13098.1 AEO65891.1 - 0.0088 16.2 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain CHORD PF04968.7 AEO65892.1 - 1.1e-51 172.9 18.2 3.3e-26 91.2 3.0 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 AEO65892.1 - 3.1e-13 50.0 0.0 5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 CS domain TALPID3 PF15324.1 AEO65892.1 - 3.3 4.9 7.1 4.8 4.3 4.9 1.2 1 0 0 1 1 1 0 Hedgehog signalling target WH2 PF02205.15 AEO65894.1 - 9.2e-12 44.1 0.3 9.2e-12 44.1 0.2 2.6 3 0 0 3 3 3 1 WH2 motif RRM_1 PF00076.17 AEO65897.1 - 1e-41 140.3 0.3 1.5e-20 72.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO65897.1 - 9.7e-35 118.3 0.0 7.4e-18 64.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO65897.1 - 2.9e-20 71.8 0.0 4.9e-11 42.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDUFB10 PF10249.4 AEO65898.1 - 0.00056 20.0 0.1 0.0006 19.9 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.9 AEO65898.1 - 0.058 13.8 0.0 0.088 13.2 0.0 1.2 1 0 0 1 1 1 0 HWE histidine kinase Ribosomal_L37 PF08561.5 AEO65899.1 - 4.7e-32 109.4 6.0 8.6e-25 86.1 0.3 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L37 TAFII55_N PF04658.8 AEO65900.1 - 1.3e-48 164.5 0.2 2.8e-48 163.4 0.0 1.7 2 0 0 2 2 2 1 TAFII55 protein conserved region Serglycin PF04360.7 AEO65900.1 - 0.3 10.8 1.3 0.6 9.8 0.9 1.4 1 0 0 1 1 1 0 Serglycin Nop14 PF04147.7 AEO65900.1 - 2.4 5.9 22.4 3.9 5.2 15.5 1.3 1 0 0 1 1 1 0 Nop14-like family Bromo_TP PF07524.8 AEO65901.1 - 1.1e-05 25.0 0.0 2.8e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated DUF2281 PF10047.4 AEO65901.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) Glyco_hydro_15 PF00723.16 AEO65902.1 - 1.9e-53 181.6 0.0 3.4e-51 174.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 TPT PF03151.11 AEO65903.1 - 6.7e-32 110.2 9.7 6.7e-32 110.2 6.7 2.2 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 AEO65903.1 - 0.0029 16.5 17.2 0.0029 16.5 11.9 2.0 1 1 1 2 2 2 1 UAA transporter family EamA PF00892.15 AEO65903.1 - 0.01 15.9 34.3 0.13 12.3 7.0 3.4 2 2 0 2 2 2 0 EamA-like transporter family RRM_1 PF00076.17 AEO65904.1 - 7.1e-18 64.0 0.1 1.1e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO65904.1 - 9.8e-13 47.8 0.0 1.7e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO65904.1 - 3e-05 23.7 0.1 4.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 AEO65904.1 - 0.1 12.1 0.2 0.2 11.2 0.2 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain 6PGD PF00393.14 AEO65905.1 - 7.9e-135 448.6 0.0 1e-134 448.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 AEO65905.1 - 1.4e-45 155.0 0.0 2e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ub-Mut7C PF14451.1 AEO65905.1 - 0.12 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin NAD_binding_11 PF14833.1 AEO65905.1 - 0.14 12.2 0.0 0.42 10.6 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase SWI-SNF_Ssr4 PF08549.5 AEO65906.1 - 1.9e-219 730.4 23.0 5e-121 405.1 10.7 2.0 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1750) Ribosomal_S17 PF00366.15 AEO65907.1 - 4.6e-31 106.6 1.0 7.5e-31 105.9 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.1 AEO65908.1 - 2e-291 969.3 71.5 2.6e-265 882.9 40.5 2.4 2 1 1 3 3 3 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 AEO65908.1 - 3.5e-112 374.2 6.5 7.6e-112 373.1 4.5 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein IncA PF04156.9 AEO65908.1 - 0.0013 18.3 13.5 0.0013 18.3 9.4 2.9 3 0 0 3 3 3 1 IncA protein Laminin_II PF06009.7 AEO65908.1 - 0.031 14.0 4.9 2.4 7.9 1.0 2.7 2 0 0 2 2 2 0 Laminin Domain II DUF1140 PF06600.6 AEO65908.1 - 1.6 8.8 4.3 0.38 10.9 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) Spc7_C2 PF15577.1 AEO65909.1 - 1.7e-13 49.9 0.0 2.5e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Spc7_C2 Atg14 PF10186.4 AEO65911.1 - 1.3e-85 286.9 0.0 1.5e-85 286.7 0.0 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 HAUS-augmin3 PF14932.1 AEO65911.1 - 0.052 12.7 0.6 0.085 12.0 0.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 MAP7 PF05672.6 AEO65912.1 - 0.064 12.6 2.4 0.23 10.8 0.6 2.0 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family DUF488 PF04343.8 AEO65912.1 - 0.2 12.0 3.4 0.36 11.2 0.3 2.1 1 1 0 2 2 2 0 Protein of unknown function, DUF488 DUF3807 PF12720.2 AEO65913.1 - 1.4e-48 165.3 8.1 1.6e-48 165.1 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) GAGA_bind PF06217.7 AEO65913.1 - 0.025 14.5 0.3 0.026 14.4 0.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family NAD_binding_1 PF00175.16 AEO65914.1 - 1.4e-30 106.0 0.0 2.7e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AEO65914.1 - 5.8e-22 77.6 0.0 1.1e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AEO65914.1 - 1.5e-08 34.6 0.0 0.00038 20.3 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 AEO65914.1 - 0.0022 17.9 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain SH3_9 PF14604.1 AEO65915.1 - 1.4e-08 34.1 0.2 2.6e-08 33.3 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AEO65915.1 - 2.3e-08 33.3 0.0 3.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AEO65915.1 - 1.4e-05 24.5 0.0 2.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ssu72 PF04722.8 AEO65916.1 - 2.2e-83 278.4 0.0 2.5e-83 278.2 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein GIT_SHD PF08518.6 AEO65917.1 - 1.3e-22 78.7 6.7 3.6e-14 51.8 1.5 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT APG6 PF04111.7 AEO65917.1 - 0.15 11.0 38.4 0.037 13.0 10.2 2.7 2 1 1 3 3 3 0 Autophagy protein Apg6 AAA_13 PF13166.1 AEO65917.1 - 0.3 9.5 22.9 0.078 11.4 13.3 1.8 2 0 0 2 2 2 0 AAA domain DUF4407 PF14362.1 AEO65917.1 - 1.7 7.5 27.0 0.22 10.4 12.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Rad50_zn_hook PF04423.9 AEO65917.1 - 3.6 7.1 7.7 4.6 6.8 0.8 2.9 2 0 0 2 2 2 0 Rad50 zinc hook motif MARVEL PF01284.18 AEO65918.1 - 3.9e-13 49.4 9.8 5.2e-13 49.0 6.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain Pox_I5 PF04713.7 AEO65918.1 - 0.022 14.4 0.7 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 Poxvirus protein I5 TFR_dimer PF04253.10 AEO65919.1 - 2.5e-22 78.7 0.0 4.5e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 AEO65919.1 - 4.4e-15 55.8 0.0 1.3e-14 54.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 AEO65919.1 - 4.9e-08 32.5 0.4 1.9e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 AEO65919.1 - 0.0064 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 AEO65919.1 - 0.015 14.5 0.1 0.041 13.1 0.0 1.6 2 0 0 2 2 2 0 Nicastrin MFS_1 PF07690.11 AEO65920.1 - 9.6e-33 113.3 36.2 7.6e-25 87.3 5.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily RasGAP_C PF03836.10 AEO65921.1 - 1.8e-50 170.3 3.7 5.1e-50 168.8 2.6 1.9 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 AEO65921.1 - 3.7e-42 144.2 0.0 8.3e-42 143.0 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 AEO65921.1 - 3.5e-18 63.4 45.5 0.031 13.9 2.7 13.6 14 0 0 14 14 14 8 IQ calmodulin-binding motif CH PF00307.26 AEO65921.1 - 4.8e-09 36.2 0.0 1.3e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain IMPDH PF00478.20 AEO65922.1 - 3.3e-134 447.2 3.0 3.9e-134 446.9 2.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 AEO65922.1 - 1.6e-16 59.7 0.1 4.2e-08 32.8 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 AEO65922.1 - 8.2e-10 38.3 2.8 0.00018 20.7 1.7 2.5 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 AEO65922.1 - 1.9e-08 33.5 1.5 1.8e-07 30.3 0.4 2.3 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 AEO65922.1 - 0.0012 18.1 2.3 0.064 12.5 0.1 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.9 AEO65922.1 - 0.041 12.9 1.1 0.079 12.0 0.2 1.8 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG B12-binding PF02310.14 AEO65922.1 - 0.075 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain AlaDh_PNT_N PF05222.10 AEO65923.1 - 3.2e-30 104.9 0.0 4.8e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 AEO65923.1 - 8.8e-17 61.1 0.0 1.3e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.13 AEO65924.1 - 2.9e-08 32.9 1.5 4.8e-08 32.1 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO65924.1 - 3.3e-08 33.2 10.3 5.7e-08 32.5 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3395 PF11875.3 AEO65925.1 - 0.00037 20.1 0.2 0.0009 18.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DUF1183 PF06682.7 AEO65925.1 - 0.00085 19.0 2.3 0.0054 16.3 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1183) SelP_N PF04592.9 AEO65925.1 - 0.088 12.1 3.5 0.14 11.5 2.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 AEO65925.1 - 0.18 10.8 0.8 0.26 10.2 0.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pex14_N PF04695.8 AEO65925.1 - 2.9 7.9 11.8 5.6 7.0 8.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dicty_REP PF05086.7 AEO65925.1 - 6.4 4.3 13.6 8.9 3.9 9.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Menin PF05053.8 AEO65925.1 - 7.3 4.6 11.0 13 3.7 7.6 1.3 1 0 0 1 1 1 0 Menin Pkinase PF00069.20 AEO65926.1 - 4.4e-61 206.3 0.1 5.1e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO65926.1 - 4.9e-20 71.6 0.0 6.8e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO65926.1 - 1.7e-08 34.5 0.0 8.2e-06 25.7 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO65926.1 - 0.0091 15.5 0.1 0.023 14.2 0.1 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 AEO65926.1 - 0.058 12.4 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AEO65926.1 - 0.065 12.5 0.3 0.13 11.5 0.2 1.4 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 AEO65926.1 - 0.082 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Scm3 PF10384.4 AEO65927.1 - 2.6e-21 74.8 0.1 5.2e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 V-SNARE PF05008.10 AEO65928.1 - 3.4e-23 81.5 2.5 3.4e-23 81.5 1.7 2.1 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 AEO65928.1 - 1.3e-14 53.9 2.9 1.3e-14 53.9 2.0 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Fusion_gly PF00523.13 AEO65928.1 - 0.011 13.7 2.2 0.11 10.5 0.3 2.2 2 0 0 2 2 2 0 Fusion glycoprotein F0 Spc7 PF08317.6 AEO65928.1 - 0.012 14.3 1.3 0.93 8.0 0.0 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Unstab_antitox PF09720.5 AEO65928.1 - 0.033 13.8 0.6 0.084 12.5 0.4 1.7 1 0 0 1 1 1 0 Putative addiction module component Sec20 PF03908.8 AEO65928.1 - 0.039 13.6 0.5 0.1 12.2 0.3 1.7 1 0 0 1 1 1 0 Sec20 Use1 PF09753.4 AEO65928.1 - 0.042 13.2 4.0 0.1 12.0 0.0 2.4 1 1 1 2 2 2 0 Membrane fusion protein Use1 Myosin_tail_1 PF01576.14 AEO65928.1 - 0.072 10.8 10.4 0.059 11.0 0.6 2.1 2 0 0 2 2 2 0 Myosin tail Mg296 PF09644.5 AEO65928.1 - 0.095 12.5 0.0 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 Mg296 protein YqjK PF13997.1 AEO65928.1 - 0.39 10.9 8.5 0.53 10.5 0.3 3.4 3 1 0 3 3 3 0 YqjK-like protein Synaptobrevin PF00957.16 AEO65928.1 - 2.2 7.9 5.0 6.1 6.5 3.4 1.9 1 1 0 1 1 1 0 Synaptobrevin APG6 PF04111.7 AEO65929.1 - 4.3e-129 430.0 0.0 5.2e-129 429.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 MIS13 PF08202.6 AEO65929.1 - 0.0062 15.6 10.1 0.0095 15.0 7.0 1.1 1 0 0 1 1 1 1 Mis12-Mtw1 protein family DUF342 PF03961.8 AEO65929.1 - 0.0071 14.8 1.7 0.01 14.3 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF342) DUF972 PF06156.8 AEO65929.1 - 0.053 13.8 3.8 0.043 14.1 1.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF3450 PF11932.3 AEO65929.1 - 0.1 11.8 8.1 0.19 10.9 4.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CCDC155 PF14662.1 AEO65929.1 - 0.12 11.9 13.8 0.22 11.1 9.2 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 BBS2_C PF14782.1 AEO65929.1 - 0.19 10.2 2.9 0.29 9.6 2.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal MAD PF05557.8 AEO65929.1 - 0.22 9.5 16.1 0.6 8.1 7.0 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein CENP-F_leu_zip PF10473.4 AEO65929.1 - 0.44 10.3 15.4 0.2 11.5 8.0 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.14 AEO65929.1 - 0.54 8.0 5.2 0.75 7.5 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.1 AEO65929.1 - 0.57 10.5 6.2 0.18 12.1 1.9 1.9 2 0 0 2 2 2 0 Snapin/Pallidin IncA PF04156.9 AEO65929.1 - 0.68 9.4 18.9 0.53 9.8 11.7 1.7 1 1 0 1 1 1 0 IncA protein Cep57_CLD_2 PF14197.1 AEO65929.1 - 1 9.3 20.5 0.085 12.8 6.8 2.7 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 TBPIP PF07106.8 AEO65929.1 - 1 8.9 8.1 3.3 7.2 5.6 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2968 PF11180.3 AEO65929.1 - 1.2 8.4 15.8 0.38 10.1 7.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF904 PF06005.7 AEO65929.1 - 2.5 8.4 9.9 0.81 10.0 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) CCDC-167 PF15188.1 AEO65929.1 - 3.4 7.6 9.2 20 5.1 0.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Mnd1 PF03962.10 AEO65929.1 - 4.3 6.9 14.2 38 3.8 9.9 2.1 1 1 0 1 1 1 0 Mnd1 family Microtub_bind PF13931.1 AEO65929.1 - 4.6 7.3 6.3 1.9 8.6 2.5 1.7 1 1 1 2 2 2 0 Kinesin-associated microtubule-binding Prefoldin_2 PF01920.15 AEO65929.1 - 5 6.9 11.3 0.94 9.2 4.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit TMF_DNA_bd PF12329.3 AEO65929.1 - 5 7.0 15.3 1 9.2 3.9 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1635 PF07795.6 AEO65929.1 - 5.1 6.4 6.6 8.2 5.7 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Seryl_tRNA_N PF02403.17 AEO65929.1 - 5.5 7.0 10.9 7.3 6.6 6.8 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.1 AEO65929.1 - 5.7 6.0 14.2 26 3.9 9.8 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4164 PF13747.1 AEO65929.1 - 6.6 6.9 19.0 5.4 7.2 8.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) ERM PF00769.14 AEO65929.1 - 7.7 5.9 21.0 3.3 7.1 12.6 1.7 2 1 0 2 2 1 0 Ezrin/radixin/moesin family Glyco_hydro_45 PF02015.11 AEO65930.1 - 3.3e-91 304.8 22.0 3.9e-91 304.5 15.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Het-C PF07217.6 AEO65931.1 - 6.7e-266 883.3 0.0 8.8e-266 882.9 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C LCE PF14672.1 AEO65931.1 - 0.12 12.8 1.1 0.31 11.5 0.7 1.7 1 0 0 1 1 1 0 Late cornified envelope HMG_box PF00505.14 AEO65932.1 - 1.6e-06 28.2 0.0 4.6e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AEO65932.1 - 0.00011 22.4 0.2 0.0011 19.3 0.0 2.6 2 0 0 2 2 2 1 HMG-box domain Amidohydro_1 PF01979.15 AEO65933.1 - 2e-62 211.7 2.3 2.7e-62 211.3 1.6 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 AEO65933.1 - 6e-56 187.7 5.8 3e-54 182.3 1.9 2.3 2 0 0 2 2 2 2 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 AEO65933.1 - 4.1e-39 132.4 0.2 7e-39 131.7 0.1 1.4 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 AEO65933.1 - 1.4e-11 44.2 0.0 2.8e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 AEO65933.1 - 4.4e-06 26.4 4.6 1.4e-05 24.7 3.2 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 AEO65933.1 - 9.9e-06 25.0 1.5 0.00069 18.9 0.1 2.8 2 1 0 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.9 AEO65933.1 - 0.0015 18.1 0.2 0.0086 15.6 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase DUF148 PF02520.12 AEO65934.1 - 0.26 11.0 1.7 15 5.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF148 tRNA-synt_2b PF00587.20 AEO65935.1 - 1.5e-49 167.9 0.0 2.8e-49 167.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Maf PF02545.9 AEO65935.1 - 6e-40 136.4 0.0 1.5e-39 135.1 0.0 1.6 1 1 0 1 1 1 1 Maf-like protein HGTP_anticodon PF03129.15 AEO65935.1 - 4e-06 26.6 0.0 8.2e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Glyco_hydro_47 PF01532.15 AEO65936.1 - 2.8e-13 49.3 0.1 3.2e-13 49.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Utp11 PF03998.8 AEO65937.1 - 3.2e-59 200.6 26.3 3.7e-59 200.4 18.2 1.0 1 0 0 1 1 1 1 Utp11 protein Med9 PF07544.8 AEO65937.1 - 0.0057 16.3 1.4 0.0057 16.3 1.0 2.8 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 FliD_N PF02465.13 AEO65937.1 - 0.063 13.6 2.2 1.4 9.3 0.6 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus CENP-Q PF13094.1 AEO65937.1 - 3.5 7.6 18.6 2.8 7.9 7.8 2.5 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2892 PF11127.3 AEO65938.1 - 3.7 7.4 5.3 8.6 6.2 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) DAO PF01266.19 AEO65939.1 - 4.4e-09 35.7 0.0 4.4e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AEO65939.1 - 4.3e-07 30.0 0.0 4.5e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO65939.1 - 5.6e-07 29.8 0.0 5.9e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO65939.1 - 7.6e-06 25.0 0.1 8.4e-06 24.8 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 AEO65939.1 - 1.9e-05 24.5 1.0 2.7e-05 24.1 0.7 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 AEO65939.1 - 2.2e-05 24.1 0.1 2.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 AEO65939.1 - 4.6e-05 22.8 0.0 4.6e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 AEO65939.1 - 7.1e-05 22.0 0.4 9.3e-05 21.6 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 AEO65939.1 - 0.00081 18.3 0.0 0.00081 18.3 0.0 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 AEO65939.1 - 0.00092 17.7 0.4 0.0011 17.5 0.3 1.0 1 0 0 1 1 1 1 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 AEO65939.1 - 0.0013 18.1 0.8 0.0016 17.8 0.6 1.1 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 AEO65939.1 - 0.0017 18.6 0.0 0.0017 18.5 0.0 1.1 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 AEO65939.1 - 0.0018 17.8 0.6 0.0022 17.6 0.4 1.3 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 AEO65939.1 - 0.0022 17.7 0.0 0.0022 17.7 0.0 1.0 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 AEO65939.1 - 0.0061 15.6 0.1 0.0075 15.3 0.1 1.1 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 AEO65939.1 - 0.0079 16.2 0.0 0.0079 16.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.14 AEO65939.1 - 0.011 14.7 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.13 AEO65939.1 - 0.014 15.3 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.10 AEO65939.1 - 0.016 15.0 0.0 0.018 14.8 0.0 1.0 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ldh_1_N PF00056.18 AEO65939.1 - 0.019 14.7 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 AEO65939.1 - 0.028 13.3 0.1 0.031 13.1 0.1 1.0 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_10 PF13460.1 AEO65939.1 - 0.03 14.3 0.0 0.032 14.2 0.0 1.0 1 0 0 1 1 1 0 NADH(P)-binding Glyco_transf_4 PF13439.1 AEO65939.1 - 0.037 13.7 0.0 0.04 13.6 0.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase Family 4 XdhC_C PF13478.1 AEO65939.1 - 0.039 14.2 0.0 0.04 14.2 0.0 1.1 1 0 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.12 AEO65939.1 - 0.064 13.6 0.0 0.066 13.6 0.0 1.1 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 AEO65939.1 - 0.067 12.3 0.0 0.07 12.2 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 AEO65939.1 - 0.086 12.9 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CPSase_L_chain PF00289.17 AEO65939.1 - 0.1 12.6 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain CTP_synth_N PF06418.9 AEO65939.1 - 0.11 11.5 0.0 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 CTP synthase N-terminus Amino_oxidase PF01593.19 AEO65939.1 - 0.13 11.3 0.1 0.16 10.9 0.1 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 AEO65939.1 - 0.31 10.0 1.2 0.37 9.8 0.9 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.19 AEO65940.1 - 6e-11 41.8 0.4 1e-10 41.0 0.3 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Cmc1 PF08583.5 AEO65941.1 - 3.1e-17 62.1 4.1 3.1e-17 62.1 2.8 1.9 3 0 0 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 AEO65941.1 - 0.0016 18.3 3.5 0.19 11.7 0.2 2.4 2 0 0 2 2 2 2 CHCH domain Cys_rich_FGFR PF00839.12 AEO65941.1 - 0.06 13.2 0.3 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Cysteine rich repeat CAF-1_p150 PF11600.3 AEO65941.1 - 0.51 9.6 13.1 0.67 9.2 9.1 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3128 PF11326.3 AEO65941.1 - 6.1 7.0 8.5 1.1e+02 2.9 5.9 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) fn3 PF00041.16 AEO65942.1 - 8.9e-10 38.5 0.7 1.8e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain AAA_13 PF13166.1 AEO65942.1 - 5.5 5.3 35.9 0.24 9.8 14.6 2.3 2 1 0 2 2 2 0 AAA domain LNS2 PF08235.8 AEO65943.1 - 6.8e-71 236.9 0.0 1e-70 236.3 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 AEO65943.1 - 3e-39 133.0 0.0 1.3e-38 131.0 0.0 2.0 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 AEO65943.1 - 0.0069 15.7 0.0 0.16 11.3 0.0 2.5 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) AF1Q PF15017.1 AEO65943.1 - 0.081 12.8 0.2 0.081 12.8 0.1 3.0 2 1 0 2 2 2 0 Drug resistance and apoptosis regulator TFIID-31kDa PF02291.10 AEO65944.1 - 6.5e-27 93.8 0.0 2.4e-26 92.0 0.0 1.8 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histidinol_dh PF00815.15 AEO65945.1 - 1.4e-180 600.3 6.3 1.8e-180 599.9 4.4 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 AEO65945.1 - 1.8e-25 88.3 0.1 3.4e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 AEO65945.1 - 4.6e-10 39.6 0.1 4.6e-10 39.6 0.1 2.7 4 0 0 4 4 4 1 Phosphoribosyl-ATP pyrophosphohydrolase PLA2_B PF01735.13 AEO65946.1 - 2.7e-180 599.7 0.0 3.1e-180 599.5 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain BAF1_ABF1 PF04684.8 AEO65948.1 - 3.3 6.4 7.5 5.1 5.8 4.7 1.6 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Cation_efflux PF01545.16 AEO65950.1 - 2.1e-76 256.7 3.4 1.2e-75 254.2 2.3 1.8 1 1 0 1 1 1 1 Cation efflux family GST_N_3 PF13417.1 AEO65952.1 - 3.4e-12 46.4 0.0 6.4e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 AEO65952.1 - 6.3e-11 42.2 0.0 9.8e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO65952.1 - 6.9e-11 41.9 0.0 1.8e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 AEO65952.1 - 1.9e-06 27.7 0.0 3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AEO65952.1 - 0.0082 16.6 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 AEO65952.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain F-box-like PF12937.2 AEO65953.1 - 1.3e-11 44.0 0.3 2.7e-11 43.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO65953.1 - 0.0023 17.5 0.8 0.0051 16.4 0.6 1.6 1 0 0 1 1 1 1 F-box domain MttA_Hcf106 PF02416.11 AEO65953.1 - 0.13 11.4 0.1 0.35 9.9 0.0 1.7 1 0 0 1 1 1 0 mttA/Hcf106 family MIT PF04212.13 AEO65953.1 - 0.14 12.0 0.1 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain MBOAT PF03062.14 AEO65954.1 - 4.2e-40 137.8 13.8 4.2e-40 137.8 9.5 1.8 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family ESSS PF10183.4 AEO65954.1 - 0.003 17.9 0.0 0.0092 16.3 0.0 1.8 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Far-17a_AIG1 PF04750.9 AEO65955.1 - 1.6e-06 27.4 12.7 2.4e-06 26.8 8.8 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Prefoldin_3 PF13758.1 AEO65958.1 - 9.2e-33 111.9 0.5 2.8e-32 110.4 0.3 1.9 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 AEO65958.1 - 7.1e-25 87.7 9.5 1.8e-19 70.4 0.0 5.1 5 1 0 5 5 5 2 Domain of unknown function (DUF3835) MIS13 PF08202.6 AEO65958.1 - 0.004 16.2 0.7 0.009 15.1 0.5 1.5 1 0 0 1 1 1 1 Mis12-Mtw1 protein family BTV_NS2 PF04514.7 AEO65958.1 - 0.0082 15.0 4.6 0.015 14.1 3.2 1.4 1 0 0 1 1 1 1 Bluetongue virus non-structural protein NS2 CS PF04969.11 AEO65959.1 - 2.4e-18 66.4 0.1 7.4e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 CS domain MAT1 PF06391.8 AEO65960.1 - 8.5e-30 103.8 4.6 1.1e-29 103.4 3.2 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 AEO65960.1 - 0.0011 18.5 5.5 0.0026 17.3 3.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO65960.1 - 0.0015 18.1 6.6 0.0023 17.5 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO65960.1 - 0.0058 16.3 10.0 0.064 12.9 7.3 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 AEO65960.1 - 0.011 15.5 6.8 0.051 13.4 4.9 1.9 1 1 1 2 2 2 0 Ring finger domain MRP-S26 PF14943.1 AEO65960.1 - 0.012 15.2 15.0 0.018 14.6 10.4 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 zf-C3HC4_2 PF13923.1 AEO65960.1 - 0.016 15.2 8.3 0.056 13.4 5.9 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) eIF-3_zeta PF05091.7 AEO65960.1 - 0.058 12.0 4.2 0.076 11.6 2.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Atg14 PF10186.4 AEO65960.1 - 0.059 12.3 2.9 0.086 11.7 2.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zf-RING_4 PF14570.1 AEO65960.1 - 0.37 10.4 9.9 6.3 6.4 7.5 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 AEO65960.1 - 0.44 10.4 8.0 2.2 8.2 5.7 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING OmpH PF03938.9 AEO65960.1 - 2.8 7.8 7.5 4.6 7.1 5.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Oxidored-like PF09791.4 AEO65960.1 - 4.1 6.9 6.2 4.3 6.8 2.8 2.1 1 1 1 2 2 2 0 Oxidoreductase-like protein, N-terminal DUF4407 PF14362.1 AEO65960.1 - 5.5 5.8 12.0 8.7 5.1 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ANTH PF07651.11 AEO65961.1 - 7.6e-72 241.3 0.7 1e-71 240.9 0.5 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 AEO65961.1 - 4.7e-08 32.9 0.0 8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 ENTH domain tRNA-synt_2 PF00152.15 AEO65962.1 - 2.3e-99 332.3 0.0 3.1e-99 331.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 AEO65962.1 - 0.086 12.4 0.0 6.7 6.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) MIP-T3 PF10243.4 AEO65963.1 - 0.14 10.6 16.3 0.2 10.0 11.3 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 p450 PF00067.17 AEO65965.1 - 8.3e-75 252.0 0.0 9.8e-75 251.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 AEO65966.1 - 3.4e-41 141.1 50.0 3.9e-41 140.9 33.9 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TFIIS_M PF07500.9 AEO65967.1 - 5e-25 87.8 0.8 1.1e-23 83.5 0.0 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 AEO65967.1 - 2.4e-18 65.4 8.5 4.4e-18 64.6 5.8 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 AEO65967.1 - 3.9e-14 51.8 3.4 5.8e-14 51.3 0.3 2.6 3 0 0 3 3 3 1 TFIIS helical bundle-like domain ATP-synt_B PF00430.13 AEO65967.1 - 0.22 11.2 7.2 0.41 10.4 2.1 2.4 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) MRP-S31 PF15433.1 AEO65967.1 - 2.4 7.5 6.9 0.52 9.6 1.1 2.0 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 PALP PF00291.20 AEO65968.1 - 3.1e-53 181.0 1.0 3.9e-53 180.6 0.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.12 AEO65969.1 - 3.4e-37 128.2 0.0 5e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 AEO65969.1 - 0.011 14.6 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase tRNA-synt_2c PF01411.14 AEO65970.1 - 8.8e-213 707.5 0.2 3e-212 705.8 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 AEO65970.1 - 3.2e-16 58.9 0.4 8.7e-16 57.5 0.3 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 AEO65970.1 - 0.0053 16.4 0.3 0.02 14.5 0.2 2.1 1 0 0 1 1 1 1 DHHA1 domain RCR PF12273.3 AEO65972.1 - 6.7e-12 46.0 6.0 8.1e-12 45.8 4.1 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SpoIIE PF07228.7 AEO65973.1 - 1.4e-10 41.2 0.3 2.2e-09 37.3 0.1 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 AEO65973.1 - 2e-10 40.5 0.0 0.00013 21.4 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 AEO65973.1 - 5.5e-07 29.2 0.0 9.1e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C DUF4614 PF15391.1 AEO65974.1 - 0.44 10.3 17.3 0.76 9.5 12.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Spc7_N PF15402.1 AEO65974.1 - 1.4 6.8 17.1 1.7 6.5 11.8 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Herpes_TAF50 PF03326.8 AEO65974.1 - 1.4 7.7 15.7 1.5 7.6 10.9 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF605 PF04652.11 AEO65974.1 - 1.6 8.0 15.4 1.8 7.8 10.7 1.1 1 0 0 1 1 1 0 Vta1 like Sec3_C PF09763.4 AEO65974.1 - 1.8 6.5 5.3 2.1 6.3 3.6 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF572 PF04502.8 AEO65974.1 - 6.5 5.8 7.1 8 5.5 4.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Period_C PF12114.3 AEO65974.1 - 7.2 6.1 18.2 10 5.7 12.6 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Macoilin PF09726.4 AEO65974.1 - 7.4 4.7 14.0 8.8 4.4 9.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Pyr_redox_3 PF13738.1 AEO65976.1 - 1.1e-20 74.5 0.0 4.3e-20 72.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AEO65976.1 - 1.1e-10 40.3 0.0 9.7e-10 37.2 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 AEO65976.1 - 1e-08 35.0 0.0 2.7e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 AEO65976.1 - 8.7e-07 28.1 0.0 0.00062 18.7 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 AEO65976.1 - 0.00012 21.9 0.0 0.01 15.7 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO65976.1 - 0.00047 19.9 0.0 0.11 12.2 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.17 AEO65976.1 - 0.091 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Complex1_LYR PF05347.10 AEO65977.1 - 4.7e-08 32.7 0.2 1.2e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AEO65977.1 - 2e-06 27.9 0.2 3.5e-06 27.1 0.1 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 AEO65977.1 - 3.2e-05 24.3 0.2 4.3e-05 23.9 0.1 1.3 1 1 0 1 1 1 1 Complex1_LYR-like HA2 PF04408.18 AEO65978.1 - 2.4e-18 66.0 0.0 4.9e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AEO65978.1 - 1.2e-15 57.3 0.0 2.8e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AEO65978.1 - 6e-14 51.6 0.0 1.4e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AEO65978.1 - 2e-06 27.3 0.0 1.1e-05 24.9 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AEO65978.1 - 8.4e-05 22.7 0.0 0.00022 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO65978.1 - 0.0087 16.0 0.8 0.62 10.0 0.0 3.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 AEO65978.1 - 0.022 14.2 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 AEO65978.1 - 0.071 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 AEO65978.1 - 0.091 13.0 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 AEO65978.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SNARE PF05739.14 AEO65979.1 - 0.0071 16.0 11.1 0.22 11.2 4.5 2.8 2 0 0 2 2 2 2 SNARE domain GARS_C PF02843.11 AEO65979.1 - 0.026 14.6 0.6 0.058 13.5 0.4 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain GTP_EFTU PF00009.22 AEO65980.1 - 1.3e-08 34.5 0.0 5.4e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 AEO65980.1 - 0.019 14.4 0.3 0.045 13.2 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 AEO65980.1 - 0.33 10.4 0.8 14 5.0 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Rab5ip PF07019.7 AEO65981.1 - 7.7e-24 83.6 3.6 1.1e-23 83.1 2.5 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Vezatin PF12632.2 AEO65982.1 - 1.2e-61 208.0 0.1 1.8e-61 207.4 0.1 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes PCNA_N PF00705.13 AEO65983.1 - 6.6e-56 187.2 3.5 6.6e-56 187.2 2.5 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 AEO65983.1 - 4.1e-51 172.2 0.2 1.5e-50 170.4 0.0 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 AEO65983.1 - 4.2e-10 39.1 0.1 5.1e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 AEO65983.1 - 4.4e-06 25.6 1.0 0.00025 19.8 0.7 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 AEO65983.1 - 0.00017 20.6 0.4 0.0025 16.8 0.1 2.0 1 1 1 2 2 2 1 Hus1-like protein IL12p40_C PF10420.4 AEO65983.1 - 0.08 13.0 0.1 0.38 10.8 0.0 2.1 3 0 0 3 3 3 0 Cytokine interleukin-12p40 C-terminus Phos_pyr_kin PF08543.7 AEO65984.1 - 8.6e-11 41.4 0.0 2.4e-10 40.0 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 AEO65984.1 - 7.2e-08 31.9 0.0 7.3e-07 28.6 0.0 2.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase dUTPase PF00692.14 AEO65985.1 - 7.2e-45 151.5 0.0 9e-45 151.2 0.0 1.1 1 0 0 1 1 1 1 dUTPase CENP-K PF11802.3 AEO65986.1 - 1.1e-11 44.4 1.3 2.5e-07 30.2 0.0 2.4 2 1 0 2 2 2 2 Centromere-associated protein K Syntaxin_2 PF14523.1 AEO65986.1 - 0.035 14.1 2.5 0.25 11.3 0.3 2.8 3 1 0 3 3 3 0 Syntaxin-like protein T2SF PF00482.18 AEO65986.1 - 0.14 12.0 0.3 0.14 12.0 0.2 2.5 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein F GSH_synthase PF03199.10 AEO65986.1 - 0.2 11.7 1.5 0.26 11.3 0.2 1.8 2 0 0 2 2 2 0 Eukaryotic glutathione synthase K-box PF01486.12 AEO65986.1 - 0.26 11.0 0.1 0.26 11.0 0.1 3.1 2 1 1 3 3 3 0 K-box region OmpH PF03938.9 AEO65986.1 - 0.67 9.8 22.2 1.3 8.9 7.0 3.0 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF904 PF06005.7 AEO65986.1 - 1 9.7 12.3 5.6 7.3 5.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Exonuc_VII_L PF02601.10 AEO65986.1 - 1 8.4 5.5 4.7 6.2 3.8 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit GldM_N PF12081.3 AEO65986.1 - 1.6 8.1 5.8 2.2 7.7 0.0 2.8 3 1 0 3 3 3 0 GldM N-terminal domain COG2 PF06148.6 AEO65986.1 - 5.6 6.8 11.2 14 5.5 0.2 3.0 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6 PF04111.7 AEO65986.1 - 9.2 5.2 13.1 2.3 7.1 4.6 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 KH_1 PF00013.24 AEO65987.1 - 1.7e-40 136.4 8.2 1.5e-16 59.7 1.0 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 AEO65987.1 - 2.7e-31 106.6 12.5 2.6e-11 42.8 2.8 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 AEO65987.1 - 7.2e-13 47.8 5.5 0.0028 17.1 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 AEO65987.1 - 0.00011 21.7 2.6 0.95 9.1 0.1 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 AEO65987.1 - 0.0051 16.5 6.7 0.79 9.5 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain Peptidase_C12 PF01088.16 AEO65989.1 - 1.2e-11 44.2 0.0 1.7e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Nucleo_P87 PF07267.6 AEO65990.1 - 0.011 14.4 0.1 0.013 14.1 0.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2383 PF09537.5 AEO65990.1 - 0.028 14.6 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) SBF PF01758.11 AEO65991.1 - 1.9e-45 154.5 12.5 6.1e-45 152.9 8.0 2.1 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF1765 PF08578.5 AEO65992.1 - 2.5e-49 166.5 0.5 4e-49 165.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Period_C PF12114.3 AEO65992.1 - 0.54 9.8 4.7 1.7 8.2 3.2 1.8 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Cys_Met_Meta_PP PF01053.15 AEO65993.1 - 1.6e-106 355.8 0.0 1.9e-106 355.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 AEO65993.1 - 1.3e-05 24.1 0.4 3.8e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 AEO65993.1 - 5.9e-05 22.1 0.1 9.9e-05 21.4 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.11 AEO65993.1 - 0.0088 14.7 0.1 0.0088 14.7 0.1 1.6 2 0 0 2 2 2 1 Glycine cleavage system P-protein Zn_clus PF00172.13 AEO65995.1 - 3.2e-08 33.3 10.1 6.3e-08 32.3 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO65995.1 - 4.9e-06 25.4 0.6 8.7e-06 24.5 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Brix PF04427.13 AEO65996.1 - 8e-37 126.7 0.0 1.3e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Brix domain MFS_1 PF07690.11 AEO65998.1 - 4.8e-30 104.4 42.3 5.2e-29 101.0 13.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MOZART2 PF12926.2 AEO65998.1 - 0.16 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF1275 PF06912.6 AEO66000.1 - 6.6e-44 149.6 17.5 8e-44 149.3 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Helicase_C PF00271.26 AEO66002.1 - 1.8e-21 75.7 0.0 6.8e-18 64.3 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 AEO66002.1 - 9.5e-19 67.5 0.0 3.3e-18 65.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.5 AEO66002.1 - 1.8e-06 27.6 0.0 4.1e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 RQC domain ResIII PF04851.10 AEO66002.1 - 0.00093 19.0 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HRDC PF00570.18 AEO66002.1 - 0.0025 17.4 0.0 0.0091 15.6 0.0 2.0 1 0 0 1 1 1 1 HRDC domain SNF2_N PF00176.18 AEO66002.1 - 0.035 12.8 0.2 0.066 11.9 0.0 1.5 2 0 0 2 2 2 0 SNF2 family N-terminal domain KAR9 PF08580.5 AEO66004.1 - 4.1e-150 501.2 1.6 4.1e-150 501.2 1.1 2.1 2 0 0 2 2 2 1 Yeast cortical protein KAR9 DUF3829 PF12889.2 AEO66004.1 - 0.0016 17.7 4.6 0.11 11.6 0.1 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3829) Syntaxin-6_N PF09177.6 AEO66004.1 - 0.012 15.9 9.9 0.18 12.2 0.4 4.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF4618 PF15397.1 AEO66004.1 - 3.1 7.0 9.0 0.1 11.8 0.6 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) DUF1282 PF06930.7 AEO66006.1 - 9.8e-05 22.0 0.1 0.0001 22.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) Yip1 PF04893.12 AEO66006.1 - 0.012 15.1 0.2 0.013 15.0 0.2 1.1 1 0 0 1 1 1 0 Yip1 domain AA_permease_2 PF13520.1 AEO66006.1 - 0.022 13.3 0.1 0.026 13.0 0.1 1.0 1 0 0 1 1 1 0 Amino acid permease DUF4064 PF13273.1 AEO66006.1 - 0.065 13.3 1.6 0.41 10.7 1.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2298 PF10060.4 AEO66006.1 - 0.12 11.1 0.1 0.15 10.9 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) SVM_signal PF12113.3 AEO66006.1 - 7.2 6.5 7.2 0.36 10.7 1.2 1.6 2 0 0 2 2 2 0 SVM protein signal sequence Sod_Cu PF00080.15 AEO66007.1 - 3.3e-14 53.2 0.0 7.5e-14 52.0 0.0 1.7 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Aminotran_5 PF00266.14 AEO66009.1 - 6e-17 61.4 0.0 8.6e-09 34.5 0.0 3.6 2 1 0 2 2 2 2 Aminotransferase class-V Zn_clus PF00172.13 AEO66011.1 - 3e-07 30.2 7.4 4.5e-07 29.6 5.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF202 PF02656.10 AEO66012.1 - 0.00046 20.3 3.1 0.0015 18.6 1.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DAD PF02109.11 AEO66013.1 - 1.9e-26 92.3 0.0 2.6e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 DAD family DUF1180 PF06679.7 AEO66013.1 - 6.8 6.5 11.3 25 4.7 7.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) GRASP55_65 PF04495.9 AEO66014.1 - 4e-48 162.9 0.0 3.8e-47 159.7 0.0 2.0 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain Methyltransf_15 PF09445.5 AEO66015.1 - 4.2e-45 153.2 0.0 5.5e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 AEO66015.1 - 1.6e-08 34.5 0.1 2.5e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO66015.1 - 1.1e-07 32.3 0.0 2e-07 31.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 AEO66015.1 - 1e-06 28.5 0.0 1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 AEO66015.1 - 7e-06 25.5 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 RrnaAD PF00398.15 AEO66015.1 - 1.5e-05 24.1 0.0 1.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase UPF0020 PF01170.13 AEO66015.1 - 2.3e-05 24.0 0.0 5.1e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 MTS PF05175.9 AEO66015.1 - 0.00066 19.1 0.0 0.0009 18.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.12 AEO66015.1 - 0.00082 18.4 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 AEO66015.1 - 0.013 15.1 0.0 0.048 13.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 AEO66015.1 - 0.019 13.6 0.0 0.019 13.6 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DNA_methylase PF00145.12 AEO66015.1 - 0.046 12.8 0.1 0.058 12.5 0.0 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase MethyltransfD12 PF02086.10 AEO66015.1 - 0.078 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase PrmA PF06325.8 AEO66015.1 - 0.11 11.5 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Mon1 PF03164.9 AEO66017.1 - 7.3e-113 377.2 0.0 1.4e-112 376.3 0.0 1.4 1 1 0 1 1 1 1 Trafficking protein Mon1 Thioredoxin PF00085.15 AEO66019.1 - 2.8e-61 203.6 9.6 9.4e-32 108.8 0.2 4.1 4 1 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 AEO66019.1 - 5.6e-54 182.7 4.3 1.1e-38 132.8 0.6 3.4 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 AEO66019.1 - 4.9e-12 45.7 0.8 0.00019 21.3 0.0 4.0 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_8 PF13905.1 AEO66019.1 - 5.9e-12 45.5 0.1 0.00016 21.6 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 AEO66019.1 - 4e-11 43.0 5.6 0.00027 21.0 0.1 4.7 2 2 1 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.5 AEO66019.1 - 2e-10 40.3 4.7 0.00065 19.2 0.0 3.5 3 0 0 3 3 3 3 Redoxin AhpC-TSA PF00578.16 AEO66019.1 - 2.7e-10 39.9 2.9 0.002 17.7 0.1 3.7 3 0 0 3 3 3 3 AhpC/TSA family Calsequestrin PF01216.12 AEO66019.1 - 3.3e-08 32.7 2.2 5.7e-08 31.9 1.5 1.4 1 0 0 1 1 1 1 Calsequestrin ERp29_N PF07912.8 AEO66019.1 - 3.9e-05 23.5 3.7 2.4 8.1 0.1 4.7 4 1 0 4 4 4 2 ERp29, N-terminal domain Thioredoxin_4 PF13462.1 AEO66019.1 - 0.0082 16.1 6.0 0.72 9.8 0.5 3.7 3 2 0 3 3 3 2 Thioredoxin DSBA PF01323.15 AEO66019.1 - 0.011 15.3 0.7 0.83 9.1 0.1 3.3 3 1 0 3 3 3 0 DSBA-like thioredoxin domain DUF1215 PF06744.7 AEO66019.1 - 0.11 12.1 0.4 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1215) zf-HIT PF04438.11 AEO66021.1 - 1.7e-09 37.1 4.5 2.5e-09 36.6 3.1 1.3 1 0 0 1 1 1 1 HIT zinc finger WLM PF08325.5 AEO66023.1 - 6.3e-53 179.4 0.1 1.5e-52 178.1 0.0 1.6 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 AEO66023.1 - 2.2e-08 34.1 0.5 5.7e-08 32.8 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 CHGN PF05679.11 AEO66023.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase Ribosomal_60s PF00428.14 AEO66023.1 - 0.2 12.0 6.4 0.41 11.0 4.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4110 PF13422.1 AEO66024.1 - 6.8e-28 96.3 0.3 6.8e-28 96.3 0.2 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 AEO66024.1 - 1.3e-27 95.2 12.2 5.4e-09 35.9 0.0 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 AEO66024.1 - 7.3e-20 70.4 17.6 0.00016 21.3 0.0 6.4 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 AEO66024.1 - 7.5e-19 67.2 1.8 9.7e-07 28.6 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 AEO66024.1 - 1.4e-14 53.3 0.1 4e-06 26.2 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 AEO66024.1 - 9.7e-14 50.8 1.7 0.00047 20.2 0.1 5.5 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 AEO66024.1 - 1.6e-13 49.8 0.6 0.02 14.6 0.0 6.0 5 1 0 5 5 5 3 Kelch motif DUF2763 PF10961.3 AEO66024.1 - 0.15 12.4 6.4 0.61 10.5 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) SRP-alpha_N PF04086.8 AEO66024.1 - 9.1 5.5 24.1 0.2 11.0 5.2 2.5 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Peptidase_M1 PF01433.15 AEO66025.1 - 4.2e-140 467.2 0.0 6.5e-140 466.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 AEO66025.1 - 2.3e-96 322.8 0.0 4.1e-96 322.0 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 AEO66025.1 - 2.7e-20 72.7 0.2 5.4e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Pkinase PF00069.20 AEO66027.1 - 4.9e-23 81.6 0.0 2.1e-22 79.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO66027.1 - 8.1e-09 34.9 0.0 1.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO66027.1 - 0.065 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RVT_1 PF00078.22 AEO66028.1 - 0.00064 19.1 0.4 0.00065 19.1 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 AEO66029.1 - 0.021 14.1 0.9 0.025 13.9 0.3 1.3 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ycf54 PF10674.4 AEO66029.1 - 0.023 14.7 0.1 0.033 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) Enolase_C PF00113.17 AEO66030.1 - 2.2e-154 512.7 0.0 2.9e-154 512.3 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 AEO66030.1 - 7.6e-58 194.1 0.2 1.4e-57 193.2 0.1 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 AEO66030.1 - 0.017 14.0 0.2 0.83 8.5 0.1 2.7 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 AEO66030.1 - 0.026 15.0 0.0 0.054 14.0 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Mad3_BUB1_I PF08311.7 AEO66031.1 - 1.2e-44 151.0 0.1 2.7e-44 150.0 0.1 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 AEO66031.1 - 1.3e-09 37.6 0.0 5.5e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO66031.1 - 0.019 14.0 0.0 0.061 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase AP_endonuc_2 PF01261.19 AEO66032.1 - 1.3e-32 112.8 0.4 1.9e-32 112.2 0.2 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel F-box-like PF12937.2 AEO66033.1 - 3.7e-05 23.3 0.0 0.0001 21.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like DUF2415 PF10313.4 AEO66033.1 - 0.027 14.1 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) F-box PF00646.28 AEO66033.1 - 0.067 12.8 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 F-box domain RRM_1 PF00076.17 AEO66034.1 - 4.3e-17 61.5 0.0 2.4e-16 59.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO66034.1 - 6e-12 45.3 0.0 1.1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO66034.1 - 2e-05 24.3 0.0 4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 AEO66034.1 - 0.0026 18.1 33.8 0.0026 18.1 14.8 4.3 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 GRP PF07172.6 AEO66034.1 - 4.5 7.8 14.4 9.1 6.8 10.0 1.5 1 0 0 1 1 1 0 Glycine rich protein family DEAD PF00270.24 AEO66035.1 - 2.1e-44 150.9 2.2 2.8e-44 150.5 0.9 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO66035.1 - 1.2e-27 95.5 0.3 6.2e-27 93.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO66035.1 - 0.0012 18.7 0.0 0.003 17.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 AEO66035.1 - 0.0022 17.6 0.1 0.0063 16.1 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AEO66035.1 - 0.0066 16.5 0.1 0.02 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO66035.1 - 0.022 14.5 0.1 0.077 12.7 0.0 1.9 1 1 0 1 1 1 0 Part of AAA domain CMS1 PF14617.1 AEO66035.1 - 0.044 12.8 0.0 0.092 11.8 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.9 AEO66035.1 - 0.08 12.7 0.1 0.35 10.6 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain Fanconi_A PF03511.9 AEO66035.1 - 0.11 12.3 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Fanconi anaemia group A protein Cupin_8 PF13621.1 AEO66036.1 - 6.1e-18 65.2 0.0 7.3e-17 61.6 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 AEO66036.1 - 2.2e-10 40.8 0.0 5.9e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 AEO66036.1 - 7.5e-07 28.7 0.5 1.8e-06 27.5 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO66036.1 - 2.8e-05 23.6 0.3 7.2e-05 22.3 0.2 1.8 1 0 0 1 1 1 1 F-box domain Cupin_4 PF08007.7 AEO66036.1 - 0.025 13.8 0.0 0.071 12.3 0.0 1.7 2 0 0 2 2 2 0 Cupin superfamily protein DUF1771 PF08590.5 AEO66037.1 - 5.8e-14 51.8 10.5 1.9e-13 50.2 7.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 AEO66037.1 - 1.3e-09 38.1 1.3 4.9e-09 36.2 0.0 2.8 4 0 0 4 4 4 1 Smr domain zf-CCCH PF00642.19 AEO66037.1 - 8.5e-08 31.7 1.7 0.0035 16.9 0.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 AEO66037.1 - 0.0012 18.9 0.3 0.023 14.7 0.0 2.4 2 0 0 2 2 2 1 HBS1 N-terminus SNARE_assoc PF09335.6 AEO66038.1 - 4.9e-14 52.5 9.0 4.9e-14 52.5 6.2 2.2 1 1 1 2 2 2 1 SNARE associated Golgi protein TMF_DNA_bd PF12329.3 AEO66039.1 - 0.036 13.8 1.4 4.1 7.2 0.1 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Abhydrolase_6 PF12697.2 AEO66040.1 - 2.5e-17 63.5 4.8 1.1e-16 61.3 3.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO66040.1 - 1.1e-12 48.0 0.3 1.8e-12 47.2 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO66040.1 - 2.6e-09 36.9 0.0 5.2e-08 32.7 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.7 AEO66040.1 - 0.0053 15.3 0.0 0.0074 14.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Esterase PF00756.15 AEO66040.1 - 0.023 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase BTB PF00651.26 AEO66041.1 - 1.5e-06 28.2 0.0 2.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RasGEF_N_2 PF14663.1 AEO66041.1 - 0.065 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DEAD PF00270.24 AEO66042.1 - 2.3e-20 72.7 0.0 8.1e-20 70.9 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO66042.1 - 6.1e-07 29.2 0.0 1.7e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 AEO66042.1 - 2.7e-05 24.2 0.1 9.4e-05 22.5 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain ResIII PF04851.10 AEO66042.1 - 2.8e-05 24.0 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HTH_psq PF05225.11 AEO66042.1 - 0.019 14.5 0.0 0.086 12.4 0.0 2.1 2 0 0 2 2 2 0 helix-turn-helix, Psq domain zf-HC5HC2H_2 PF13832.1 AEO66043.1 - 8.8e-19 67.5 1.3 8.8e-19 67.5 0.9 4.3 3 1 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 AEO66043.1 - 4.4e-17 61.9 2.2 4.4e-17 61.9 1.5 4.8 5 0 0 5 5 5 1 PHD-like zinc-binding domain BAH PF01426.13 AEO66043.1 - 6.4e-17 61.3 0.0 1.2e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 AEO66043.1 - 5.7e-11 41.9 61.7 5.4e-07 29.1 4.0 6.4 7 0 0 7 7 7 3 PHD-finger PHD_2 PF13831.1 AEO66043.1 - 1.4e-09 37.0 4.2 1.4e-09 37.0 2.9 5.7 7 0 0 7 7 7 2 PHD-finger C1_1 PF00130.17 AEO66043.1 - 0.0013 18.4 1.1 0.0013 18.4 0.7 5.7 5 1 1 6 6 6 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Myb_DNA-binding PF00249.26 AEO66043.1 - 0.0019 18.1 0.9 0.011 15.7 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Prok-RING_1 PF14446.1 AEO66043.1 - 0.39 10.4 50.3 0.071 12.8 1.4 4.8 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 DnaJ PF00226.26 AEO66044.1 - 1.1e-26 92.2 1.4 2.3e-26 91.3 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AEO66044.1 - 8e-21 73.7 0.0 7.9e-18 64.1 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AEO66044.1 - 1.1e-13 50.9 16.6 1.1e-13 50.9 11.5 1.7 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.14 AEO66044.1 - 0.0071 16.0 8.8 0.21 11.3 1.3 2.3 1 1 1 2 2 2 2 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 AEO66044.1 - 0.22 11.3 5.6 4.1 7.2 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbons zf-RING_3 PF14369.1 AEO66044.1 - 1.3 9.1 6.8 25 4.9 0.0 3.6 4 0 0 4 4 4 0 zinc-finger DUF2614 PF11023.3 AEO66044.1 - 2.3 8.0 5.5 12 5.7 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) Lar_restr_allev PF14354.1 AEO66044.1 - 2.5 8.4 8.6 36 4.7 6.1 2.6 1 1 0 1 1 1 0 Restriction alleviation protein Lar Opy2 PF09463.5 AEO66044.1 - 3.2 7.9 5.9 13 6.0 0.5 3.1 3 0 0 3 3 3 0 Opy2 protein WD40 PF00400.27 AEO66045.1 - 3.4e-06 26.7 0.0 0.0024 17.7 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat CPSF_A PF03178.10 AEO66045.1 - 0.008 15.2 0.0 0.016 14.2 0.0 1.5 2 0 0 2 2 2 1 CPSF A subunit region Ribosomal_L10 PF00466.15 AEO66046.1 - 3.2e-25 87.9 0.1 8e-25 86.6 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 AEO66046.1 - 2.4e-18 66.3 6.8 2.4e-18 66.3 4.7 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein VirE_N PF08800.5 AEO66046.1 - 0.067 12.9 0.0 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 VirE N-terminal domain MutS_V PF00488.16 AEO66047.1 - 7.5e-79 264.4 0.0 1.2e-78 263.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AEO66047.1 - 2.1e-27 96.2 0.0 3.9e-26 92.1 0.0 2.4 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.15 AEO66047.1 - 6.6e-20 71.2 0.0 9.3e-19 67.5 0.0 2.5 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 AEO66047.1 - 3.5e-08 33.5 0.0 9.8e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 AEO66047.1 - 0.0074 15.7 0.0 0.023 14.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 AEO66047.1 - 0.023 14.8 0.4 0.23 11.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 AEO66047.1 - 0.29 11.4 0.1 1.1 9.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain HemX PF04375.9 AEO66048.1 - 0.043 12.4 0.5 0.064 11.8 0.4 1.2 1 0 0 1 1 1 0 HemX zf-C4H2 PF10146.4 AEO66048.1 - 5.8 6.8 5.3 9.7 6.1 3.7 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Glyco_hydro_38 PF01074.17 AEO66050.1 - 9.2e-93 310.4 0.1 1.8e-92 309.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 AEO66050.1 - 5.1e-75 253.0 0.0 9.6e-75 252.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 AEO66050.1 - 1.5e-27 95.6 0.0 3.7e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Nop14 PF04147.7 AEO66051.1 - 1.3e-267 890.1 20.4 1.5e-267 889.8 14.1 1.0 1 0 0 1 1 1 1 Nop14-like family HEAT_2 PF13646.1 AEO66052.1 - 0.034 14.4 0.5 0.22 11.8 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats CAP_GLY PF01302.20 AEO66054.1 - 8.3e-18 63.8 0.0 4.4e-17 61.5 0.1 2.3 3 0 0 3 3 2 1 CAP-Gly domain AAA_13 PF13166.1 AEO66054.1 - 0.0014 17.1 5.9 0.0014 17.1 4.1 2.6 1 1 0 3 3 3 1 AAA domain Med4 PF10018.4 AEO66054.1 - 0.006 16.0 17.2 0.01 15.2 0.3 3.1 3 0 0 3 3 3 2 Vitamin-D-receptor interacting Mediator subunit 4 Fez1 PF06818.10 AEO66054.1 - 0.0066 16.4 29.8 0.013 15.4 10.1 3.2 3 0 0 3 3 3 1 Fez1 BLOC1_2 PF10046.4 AEO66054.1 - 0.011 15.8 1.6 0.011 15.8 1.1 3.5 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 AEO66054.1 - 0.016 15.4 8.6 0.57 10.4 1.6 3.3 3 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.6 AEO66054.1 - 0.056 12.8 14.5 0.047 13.1 1.1 3.2 4 0 0 4 4 4 0 Phage minor structural protein GP20 APG17 PF04108.7 AEO66054.1 - 0.46 9.2 10.9 0.067 11.9 4.6 1.7 2 0 0 2 2 2 0 Autophagy protein Apg17 Seryl_tRNA_N PF02403.17 AEO66054.1 - 0.62 10.1 25.5 2.3 8.2 4.6 4.5 4 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Nsp1_C PF05064.8 AEO66054.1 - 0.73 9.4 10.3 1.3 8.6 0.0 2.8 3 0 0 3 3 3 0 Nsp1-like C-terminal region Zn_ribbon_2 PF12674.2 AEO66054.1 - 1 9.7 2.8 4.3 7.7 0.0 2.9 3 0 0 3 3 2 0 Putative zinc ribbon domain TPR_MLP1_2 PF07926.7 AEO66054.1 - 1.8 8.3 28.2 0.058 13.1 7.9 3.7 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 AEO66054.1 - 2 7.5 6.3 3.5 6.7 0.3 2.7 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 AEO66054.1 - 2.2 6.8 26.7 0.71 8.4 5.7 3.3 1 1 2 4 4 4 0 Spc7 kinetochore protein Cauli_AT PF03233.8 AEO66054.1 - 2.7 7.6 4.6 1.3 8.6 0.6 2.3 2 0 0 2 2 2 0 Aphid transmission protein Pkip-1 PF06878.6 AEO66054.1 - 2.9 7.7 6.2 8.4 6.2 0.2 2.3 1 1 1 2 2 2 0 Pkip-1 protein Mod_r PF07200.8 AEO66054.1 - 3.2 7.6 18.0 0.29 11.0 3.8 3.2 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein CENP-F_leu_zip PF10473.4 AEO66054.1 - 8.2 6.2 38.9 1.7 8.4 6.3 3.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EMP24_GP25L PF01105.19 AEO66054.1 - 8.3 6.0 5.5 2.4 7.8 0.8 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Baculo_PEP_C PF04513.7 AEO66054.1 - 9.5 6.0 9.9 1.3 8.8 0.9 2.7 3 0 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.20 AEO66055.1 - 3.5e-35 121.4 0.0 1.1e-20 73.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO66055.1 - 7.6e-13 48.1 0.0 0.00028 20.0 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 AEO66055.1 - 8.9e-07 28.8 0.0 2.8e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 AEO66055.1 - 0.0023 16.9 0.0 0.96 8.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like IU_nuc_hydro PF01156.14 AEO66056.1 - 6.5e-79 265.3 0.0 7.6e-79 265.1 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.8 AEO66057.1 - 1.6e-09 37.3 8.8 1.6e-09 37.3 6.1 2.3 3 0 0 3 3 3 1 RED-like protein N-terminal region IMS PF00817.15 AEO66058.1 - 7.6e-42 142.6 0.0 1.7e-41 141.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 AEO66058.1 - 1.2e-16 60.7 0.0 2.7e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 AEO66058.1 - 1.6e-14 53.7 3.2 1.1e-07 31.7 0.1 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 AEO66058.1 - 0.0003 20.6 2.0 0.001 18.9 0.1 2.9 3 0 0 3 3 3 1 IMS family HHH motif HHH_5 PF14520.1 AEO66058.1 - 0.0027 17.8 0.8 0.022 14.9 0.1 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain MgtE_N PF03448.12 AEO66058.1 - 0.02 15.1 0.1 30 5.0 0.0 3.9 3 0 0 3 3 3 0 MgtE intracellular N domain WSC PF01822.14 AEO66059.1 - 6.7e-16 57.9 5.5 1.2e-15 57.1 3.8 1.4 1 0 0 1 1 1 1 WSC domain adh_short PF00106.20 AEO66060.1 - 7.2e-21 74.8 4.2 7.2e-21 74.8 2.9 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO66060.1 - 3.2e-12 46.4 2.1 5.2e-12 45.8 1.4 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO66060.1 - 1.6e-05 24.4 0.0 2.9e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO66060.1 - 0.001 19.1 0.7 0.0016 18.4 0.5 1.4 1 0 0 1 1 1 1 NADH(P)-binding Peptidase_M3 PF01432.15 AEO66061.1 - 6.3e-118 394.7 0.0 9e-118 394.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 AEO66061.1 - 0.016 14.6 0.1 0.025 13.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Reprolysin_2 PF13574.1 AEO66061.1 - 0.26 11.3 0.0 0.73 9.8 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like ApoO PF09769.4 AEO66062.1 - 5.4e-52 175.6 2.2 5.4e-52 175.6 1.6 2.7 3 1 0 3 3 3 1 Apolipoprotein O PRCC PF10253.4 AEO66062.1 - 0.32 11.6 2.0 0.48 11.0 1.4 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Mito_carr PF00153.22 AEO66063.1 - 1.2e-68 226.8 2.0 1.5e-22 79.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tail_P2_I PF09684.5 AEO66063.1 - 0.18 11.3 0.2 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Phage tail protein (Tail_P2_I) Chorion_3 PF05387.6 AEO66063.1 - 0.95 8.8 5.8 1.4 8.2 4.0 1.2 1 0 0 1 1 1 0 Chorion family 3 Sod_Fe_C PF02777.13 AEO66065.1 - 5.6e-11 42.2 0.0 0.00022 21.0 0.0 2.5 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Fungal_trans_2 PF11951.3 AEO66066.1 - 1.8e-73 247.3 0.0 2.2e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO66066.1 - 8.4e-08 32.0 5.6 1.4e-07 31.3 3.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_2 PF07647.12 AEO66067.1 - 0.0002 21.1 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 AEO66067.1 - 0.00098 19.2 0.1 0.0076 16.4 0.1 2.3 1 1 0 1 1 1 1 PH domain SAM_1 PF00536.25 AEO66067.1 - 0.0018 18.4 0.0 0.0039 17.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_9 PF15410.1 AEO66067.1 - 0.13 12.4 0.0 0.69 10.0 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Syndecan PF01034.15 AEO66068.1 - 0.0009 18.8 0.2 0.0017 18.0 0.2 1.3 1 0 0 1 1 1 1 Syndecan domain SKG6 PF08693.5 AEO66068.1 - 0.0022 17.2 2.0 0.0039 16.4 1.4 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.1 AEO66068.1 - 0.08 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Plasmodium_Vir PF05795.6 AEO66068.1 - 0.085 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1517 PF07466.6 AEO66068.1 - 0.25 10.2 1.1 0.51 9.2 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) CD99L2 PF12301.3 AEO66068.1 - 0.97 9.0 5.6 0.2 11.3 1.1 1.9 2 0 0 2 2 2 0 CD99 antigen like protein 2 Granulin PF00396.13 AEO66068.1 - 3.9 7.6 27.9 4.3 7.5 4.5 3.4 2 1 1 3 3 3 0 Granulin SHR3_chaperone PF08229.6 AEO66069.1 - 1.1e-65 220.2 0.1 1.7e-65 219.6 0.1 1.3 1 1 0 1 1 1 1 ER membrane protein SH3 DUF4131 PF13567.1 AEO66069.1 - 0.19 11.1 2.9 1 8.7 0.8 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) Aldo_ket_red PF00248.16 AEO66070.1 - 1.9e-57 194.2 0.0 2.2e-57 194.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF202 PF02656.10 AEO66071.1 - 2.6e-25 88.4 1.5 2.6e-25 88.4 1.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) AAA_11 PF13086.1 AEO66072.1 - 1.6e-58 198.0 0.2 6.8e-58 196.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 AEO66072.1 - 1.3e-55 187.8 0.0 6.7e-55 185.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AEO66072.1 - 4.5e-13 48.7 0.0 4.5e-13 48.7 0.0 3.0 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 AEO66072.1 - 4.9e-11 42.5 0.0 3.5e-09 36.5 0.0 2.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 AEO66072.1 - 5.5e-08 32.8 0.0 1.2e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 AEO66072.1 - 8.3e-07 28.6 0.0 0.00022 20.6 0.0 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 AEO66072.1 - 9.6e-07 28.5 0.0 0.078 12.4 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 AEO66072.1 - 2.1e-06 26.9 0.1 1.9e-05 23.8 0.1 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 AEO66072.1 - 4.5e-05 23.5 0.1 0.00092 19.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 AEO66072.1 - 0.00032 20.2 0.0 0.0049 16.3 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 AEO66072.1 - 0.0005 19.0 0.0 0.00093 18.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 AEO66072.1 - 0.00071 19.6 0.2 0.0027 17.6 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.9 AEO66072.1 - 0.00084 19.0 0.1 0.026 14.1 0.0 2.4 1 1 0 1 1 1 1 Helicase AAA_10 PF12846.2 AEO66072.1 - 0.002 17.6 0.0 0.013 14.9 0.0 2.1 1 1 1 2 2 2 1 AAA-like domain AAA_25 PF13481.1 AEO66072.1 - 0.002 17.5 0.2 0.056 12.8 0.0 2.8 2 1 0 3 3 3 1 AAA domain UvrD_C PF13361.1 AEO66072.1 - 0.0028 17.1 0.0 0.86 8.9 0.0 2.9 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 AEO66072.1 - 0.0035 16.6 0.0 0.038 13.2 0.0 2.5 3 0 0 3 3 3 1 PhoH-like protein Zot PF05707.7 AEO66072.1 - 0.0036 16.8 0.0 0.03 13.8 0.0 2.4 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) TrwB_AAD_bind PF10412.4 AEO66072.1 - 0.0092 14.6 0.0 0.016 13.8 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Flavi_DEAD PF07652.9 AEO66072.1 - 0.0093 15.7 0.0 0.033 13.9 0.0 1.9 2 0 0 2 2 2 1 Flavivirus DEAD domain FtsK_SpoIIIE PF01580.13 AEO66072.1 - 0.017 14.5 0.1 0.06 12.8 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 AEO66072.1 - 0.022 14.9 0.0 0.099 12.8 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AEO66072.1 - 0.026 14.2 0.0 0.084 12.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 AEO66072.1 - 0.03 13.7 0.0 0.075 12.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein 4HB_MCP_1 PF12729.2 AEO66072.1 - 0.032 13.5 0.1 0.056 12.7 0.1 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AAA_33 PF13671.1 AEO66072.1 - 0.033 14.0 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 AEO66072.1 - 0.058 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 AEO66072.1 - 0.095 12.5 0.0 0.77 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.1 AEO66072.1 - 0.1 12.7 0.0 5 7.3 0.0 2.7 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_17 PF13207.1 AEO66072.1 - 0.29 11.9 2.5 1.2 10.0 0.8 2.8 2 1 0 2 2 2 0 AAA domain Lzipper-MIP1 PF14389.1 AEO66073.1 - 0.12 12.4 1.0 0.29 11.2 0.1 2.1 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 MbeD_MobD PF04899.7 AEO66073.1 - 0.25 11.2 1.0 0.59 10.0 0.2 1.9 2 0 0 2 2 2 0 MbeD/MobD like PBP1_TM PF14812.1 AEO66073.1 - 0.47 10.7 6.5 2.2 8.6 2.0 3.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HATPase_c PF02518.21 AEO66074.1 - 4.6e-28 97.1 0.2 7.2e-28 96.5 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 AEO66074.1 - 5.5e-25 87.5 0.1 9.3e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 AEO66074.1 - 7.3e-05 22.6 0.3 0.00016 21.5 0.2 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 AEO66074.1 - 0.02 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Aldedh PF00171.17 AEO66077.1 - 3.8e-136 454.1 0.1 4.2e-136 453.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Asp PF00026.18 AEO66078.1 - 4e-70 236.5 0.5 4.8e-70 236.3 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO66078.1 - 1.4e-05 25.0 0.4 3.2e-05 23.9 0.3 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO66078.1 - 0.00012 22.5 2.6 0.013 16.0 0.4 3.4 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 AEO66078.1 - 0.13 11.8 0.2 0.68 9.4 0.0 2.4 3 1 0 3 3 3 0 Xylanase inhibitor C-terminal WLM PF08325.5 AEO66079.1 - 4e-46 157.2 0.0 6e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 AEO66079.1 - 0.0017 17.3 3.5 0.0017 17.3 2.5 3.6 3 1 1 4 4 4 1 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 AEO66079.1 - 0.0055 16.2 13.1 0.36 10.4 0.1 3.4 2 1 1 3 3 3 3 Sec23/Sec24 zinc finger DZR PF12773.2 AEO66079.1 - 0.018 14.8 7.6 0.058 13.2 5.3 1.8 1 1 0 1 1 1 0 Double zinc ribbon SprT-like PF10263.4 AEO66079.1 - 0.098 12.3 0.0 0.098 12.3 0.0 2.9 3 1 0 3 3 3 0 SprT-like family DUF45 PF01863.12 AEO66079.1 - 0.43 10.3 5.4 0.077 12.7 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF45 APC_CDC26 PF10471.4 AEO66080.1 - 5.3e-12 46.2 0.3 5.3e-12 46.2 0.2 4.3 3 1 1 4 4 4 1 Anaphase-promoting complex APC subunit 1 Nucleoplasmin PF03066.10 AEO66080.1 - 0.14 11.7 4.1 0.16 11.4 0.4 2.1 2 0 0 2 2 2 0 Nucleoplasmin DUF605 PF04652.11 AEO66080.1 - 4.6 6.5 31.7 8.6 5.6 22.0 1.5 1 0 0 1 1 1 0 Vta1 like Peptidase_M1 PF01433.15 AEO66081.1 - 1.2e-07 31.1 0.0 0.023 13.7 0.0 3.3 3 0 0 3 3 3 3 Peptidase family M1 HEAT PF02985.17 AEO66081.1 - 0.12 12.4 0.1 9.6 6.5 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat IBR PF01485.16 AEO66082.1 - 9.3e-08 31.8 4.6 9.3e-08 31.8 3.2 4.5 3 2 0 3 3 3 2 IBR domain SAS4 PF15460.1 AEO66083.1 - 2.9e-33 113.7 0.0 1e-32 111.9 0.0 2.0 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Nop14 PF04147.7 AEO66083.1 - 0.88 7.4 26.4 1.3 6.8 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family VPS9 PF02204.13 AEO66085.1 - 2e-20 72.7 0.0 5.1e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 AEO66085.1 - 2.5e-14 52.9 0.2 2.9e-10 40.0 0.0 5.1 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO66085.1 - 5.7e-10 39.4 0.2 0.00036 20.9 0.0 4.8 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 AEO66085.1 - 6.4e-10 39.2 0.1 0.0026 18.0 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AEO66085.1 - 6.2e-07 29.0 0.0 0.75 10.2 0.0 6.0 6 0 0 6 6 6 1 Ankyrin repeat PX PF00787.19 AEO66085.1 - 7.9e-05 22.4 0.6 0.00024 20.8 0.0 2.0 2 0 0 2 2 2 1 PX domain Ank PF00023.25 AEO66085.1 - 0.00058 19.5 0.2 0.21 11.4 0.0 4.3 4 1 0 4 4 4 1 Ankyrin repeat MCPsignal PF00015.16 AEO66085.1 - 0.034 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain YchF-GTPase_C PF06071.8 AEO66086.1 - 3.9e-34 116.2 0.1 1.2e-33 114.7 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 AEO66086.1 - 5.5e-12 45.6 0.0 1.2e-11 44.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO66086.1 - 0.00032 20.0 0.0 0.00063 19.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 AEO66086.1 - 0.00051 19.8 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 TGS domain PPAK PF02818.10 AEO66086.1 - 0.022 14.6 0.6 0.06 13.2 0.4 1.8 1 0 0 1 1 1 0 PPAK motif MobB PF03205.9 AEO66086.1 - 0.085 12.5 0.3 4 7.1 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 AEO66086.1 - 0.11 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AEO66086.1 - 0.45 10.7 2.1 5.1 7.4 0.2 2.5 2 1 0 2 2 2 0 ABC transporter Peptidase_C97 PF05903.9 AEO66087.1 - 2e-31 108.7 0.0 2.6e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 AEO66087.1 - 0.0029 17.5 0.0 0.0047 16.8 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF3534 PF12053.3 AEO66087.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3534) 3Beta_HSD PF01073.14 AEO66088.1 - 1.7e-24 85.9 0.0 1.3e-23 83.0 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AEO66088.1 - 1.8e-12 47.2 0.0 3.6e-12 46.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO66088.1 - 2.4e-08 33.2 0.0 8.6e-08 31.4 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 AEO66088.1 - 2.1e-07 31.0 0.1 3.9e-06 27.0 0.1 2.8 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 AEO66088.1 - 0.00024 21.0 1.5 0.001 19.0 1.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO66088.1 - 0.0014 18.3 0.4 0.0045 16.6 0.3 1.8 1 1 0 1 1 1 1 KR domain DUF3933 PF13069.1 AEO66088.1 - 0.02 14.5 0.0 0.098 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) TrkA_N PF02254.13 AEO66088.1 - 0.13 12.2 0.1 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Herpes_capsid PF06112.6 AEO66089.1 - 5.3 7.0 18.6 0.48 10.4 9.7 1.6 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein RVT_1 PF00078.22 AEO66091.1 - 0.0095 15.3 0.3 0.012 14.9 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exonuc_V_gamma PF04257.9 AEO66091.1 - 0.011 13.7 0.8 0.012 13.7 0.6 1.0 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit Filament PF00038.16 AEO66092.1 - 0.0043 16.5 32.3 0.0043 16.5 22.4 6.2 3 2 2 5 5 5 4 Intermediate filament protein Ammonium_transp PF00909.16 AEO66093.1 - 5.1e-117 390.7 22.3 5.9e-117 390.5 15.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DNA_pol_B_palm PF14792.1 AEO66094.1 - 5e-33 113.4 0.0 8.9e-33 112.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 AEO66094.1 - 8.6e-23 79.8 0.1 4.2e-22 77.6 0.1 2.2 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 AEO66094.1 - 1.7e-18 65.9 0.0 3.3e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 AEO66094.1 - 1.2e-16 60.6 0.1 7.2e-16 58.1 0.2 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 AEO66094.1 - 0.011 15.8 0.1 0.13 12.4 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 AEO66094.1 - 0.013 15.8 0.1 0.036 14.3 0.1 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain FAR1 PF03101.10 AEO66094.1 - 0.22 12.0 1.2 1 9.8 0.2 2.3 2 0 0 2 2 2 0 FAR1 DNA-binding domain Mob1_phocein PF03637.12 AEO66095.1 - 2.4e-38 131.5 1.5 4.7e-22 78.4 0.1 2.1 2 0 0 2 2 2 2 Mob1/phocein family PRMT5 PF05185.11 AEO66096.1 - 2.8e-11 42.9 0.0 3.7e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PGM_PMM_I PF02878.11 AEO66097.1 - 2.7e-20 72.2 0.1 3.1e-09 36.4 0.0 3.1 3 0 0 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 AEO66097.1 - 1.5e-15 57.4 0.1 6.3e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 AEO66097.1 - 1.4e-10 41.0 0.6 3.6e-10 39.6 0.4 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 AEO66097.1 - 0.042 13.8 0.0 0.15 12.1 0.0 2.0 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III ERCC4 PF02732.10 AEO66098.1 - 6.7e-32 110.2 0.0 1.1e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 AEO66098.1 - 8.9e-05 22.5 0.0 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain Lum_binding PF00677.12 AEO66099.1 - 1e-34 118.2 0.0 3.9e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain Glyco_transf_17 PF04724.8 AEO66100.1 - 2e-48 165.2 0.0 2.9e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 Peptidase_C15 PF01470.12 AEO66101.1 - 1.4e-12 47.8 0.1 0.00045 20.1 0.0 3.0 3 0 0 3 3 3 3 Pyroglutamyl peptidase Oxidored_FMN PF00724.15 AEO66102.1 - 4.8e-72 242.7 0.0 2e-71 240.7 0.0 1.8 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DIT1_PvcA PF05141.7 AEO66102.1 - 0.12 11.6 0.1 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein MliC PF09864.4 AEO66103.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Amidoligase_2 PF12224.3 AEO66104.1 - 0.0071 15.9 0.0 1 8.9 0.0 2.8 3 0 0 3 3 3 2 Putative amidoligase enzyme DUF2401 PF10287.4 AEO66105.1 - 3.9e-72 242.5 0.1 2.7e-38 131.7 0.1 2.4 2 1 1 3 3 3 2 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 AEO66105.1 - 6.6e-26 90.2 0.1 1.2e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) XPG_N PF00752.12 AEO66106.1 - 4.1e-33 113.6 0.0 9.9e-33 112.4 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 AEO66106.1 - 5.9e-26 90.3 0.0 1.3e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 XPG I-region UIM PF02809.15 AEO66106.1 - 0.0034 16.8 5.4 0.0061 16.0 1.0 3.6 2 0 0 2 2 2 1 Ubiquitin interaction motif 5_3_exonuc PF01367.15 AEO66106.1 - 0.084 13.1 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold LSM PF01423.17 AEO66107.1 - 4.8e-08 32.4 0.0 1.1e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AEO66107.1 - 0.084 12.8 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Ataxin 2 SM domain Trs65 PF12735.2 AEO66107.1 - 0.18 11.0 1.5 0.23 10.7 1.0 1.2 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 MSP1_C PF07462.6 AEO66107.1 - 0.24 9.7 3.4 0.27 9.5 2.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Pil1 PF13805.1 AEO66108.1 - 1.6e-154 512.8 0.6 2e-154 512.5 0.4 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 AEO66108.1 - 0.047 13.0 3.0 0.16 11.2 2.1 1.8 1 1 0 1 1 1 0 FAM92 protein SET PF00856.23 AEO66109.1 - 8.9e-22 78.1 0.7 4.4e-21 75.8 0.5 2.3 1 1 0 1 1 1 1 SET domain WD40 PF00400.27 AEO66110.1 - 1.3e-31 107.2 14.3 1.8e-09 37.0 0.1 10.3 11 1 0 11 11 11 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 AEO66110.1 - 0.00044 19.1 0.0 12 4.5 0.0 4.9 4 1 0 4 4 4 3 Nup133 N terminal like Lgl_C PF08596.5 AEO66110.1 - 0.0032 15.9 0.0 0.029 12.8 0.0 2.0 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal SUR7 PF06687.7 AEO66111.1 - 1.9e-33 115.8 10.3 2.3e-33 115.5 7.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Metallophos PF00149.23 AEO66113.1 - 8.3e-39 133.0 0.1 1.1e-38 132.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_transf_22 PF03901.12 AEO66114.1 - 1e-43 149.9 23.8 1.3e-43 149.5 16.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family F_actin_cap_B PF01115.12 AEO66115.1 - 6.3e-108 359.5 0.0 7.3e-108 359.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Epimerase PF01370.16 AEO66116.1 - 5.2e-23 81.7 0.0 7.5e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 AEO66116.1 - 3.5e-09 35.9 0.0 5.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 AEO66116.1 - 3.4e-06 27.0 0.0 1.5e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 AEO66116.1 - 1.4e-05 25.1 0.0 3.6e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 AEO66116.1 - 0.0066 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 AEO66116.1 - 0.0095 14.9 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 AEO66116.1 - 0.014 14.1 0.0 0.042 12.5 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 AEO66116.1 - 0.018 13.9 0.0 0.03 13.2 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Ldh_1_N PF00056.18 AEO66116.1 - 0.14 11.9 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain CBS PF00571.23 AEO66118.1 - 0.00032 20.4 0.0 0.22 11.3 0.0 2.6 2 1 0 2 2 2 2 CBS domain Spindle_Spc25 PF08234.7 AEO66118.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 Chromosome segregation protein Spc25 DUF4350 PF14258.1 AEO66118.1 - 0.11 12.7 0.4 1.2 9.4 0.0 2.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4350) Mito_carr PF00153.22 AEO66119.1 - 1.5e-51 172.0 9.6 3e-19 68.5 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_transf_28 PF03033.15 AEO66120.1 - 1.4e-22 79.9 0.5 5e-21 74.9 0.1 3.0 2 1 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 AEO66120.1 - 0.00017 20.2 0.1 0.00026 19.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 AEO66120.1 - 0.076 12.6 0.0 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain Cwf_Cwc_15 PF04889.7 AEO66120.1 - 2.8 7.5 16.4 3.3 7.3 6.3 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein UIM PF02809.15 AEO66120.1 - 7.6 6.3 20.1 4.4 7.1 2.2 4.2 3 0 0 3 3 3 0 Ubiquitin interaction motif NAD_binding_10 PF13460.1 AEO66121.1 - 2e-18 67.0 0.1 1e-09 38.6 0.2 2.3 1 1 1 2 2 2 2 NADH(P)-binding NmrA PF05368.8 AEO66121.1 - 9.2e-09 34.8 0.0 3.6e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 NmrA-like family Epimerase PF01370.16 AEO66121.1 - 9.9e-07 28.4 0.0 0.0045 16.4 0.0 2.9 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 AEO66121.1 - 6.7e-05 23.1 0.0 0.00013 22.2 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 AEO66121.1 - 0.0066 16.3 2.0 0.016 15.1 0.0 2.4 2 1 0 3 3 3 1 short chain dehydrogenase F420_oxidored PF03807.12 AEO66121.1 - 0.044 14.2 0.7 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ribosomal_60s PF00428.14 AEO66121.1 - 0.14 12.5 14.0 0.38 11.1 9.7 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein PAF-AH_p_II PF03403.8 AEO66122.1 - 2.3e-39 134.7 0.0 1.2e-20 73.2 0.0 3.6 4 0 0 4 4 4 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 AEO66122.1 - 1.8e-12 47.1 0.1 1.6e-11 44.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO66122.1 - 9.5e-07 28.9 0.2 4.8e-06 26.6 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 AEO66122.1 - 0.00089 18.2 0.0 0.018 13.9 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 AEO66122.1 - 0.0011 17.8 0.0 0.0063 15.3 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 AEO66122.1 - 0.067 13.0 0.1 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Putative lysophospholipase Mito_carr PF00153.22 AEO66124.1 - 3.2e-59 196.6 3.2 2.1e-20 72.2 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein Ribosomal_60s PF00428.14 AEO66124.1 - 4.6 7.7 17.0 0.52 10.7 7.0 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF1708 PF08101.6 AEO66125.1 - 3.2e-64 217.3 0.0 4.1e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) UDG PF03167.14 AEO66126.1 - 6.6e-26 90.5 0.1 1e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily CDC27 PF09507.5 AEO66126.1 - 0.081 12.1 0.4 0.15 11.2 0.3 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Lectin_legB PF00139.14 AEO66126.1 - 0.15 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Legume lectin domain Metallophos PF00149.23 AEO66127.1 - 4.1e-18 65.5 0.4 7.2e-18 64.7 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_3 PF00933.16 AEO66128.1 - 2.5e-85 286.0 0.0 3.6e-85 285.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO66128.1 - 1.2e-75 253.9 0.5 9.2e-74 247.7 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO66128.1 - 4.3e-23 81.0 0.1 9e-23 80.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 AEO66128.1 - 5.4e-22 78.0 0.0 1e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 PA14 domain RRF PF01765.14 AEO66130.1 - 6.5e-25 87.5 0.1 8.3e-25 87.1 0.1 1.1 1 0 0 1 1 1 1 Ribosome recycling factor Peripla_BP_1 PF00532.16 AEO66130.1 - 0.053 12.7 0.0 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family LLC1 PF14945.1 AEO66130.1 - 2.5 8.4 5.1 0.26 11.6 0.3 1.8 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein BAH PF01426.13 AEO66131.1 - 4e-06 26.5 0.1 7.1e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 AEO66131.1 - 0.0035 16.9 2.3 0.0088 15.7 1.6 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.6 AEO66131.1 - 0.057 13.4 0.3 0.15 12.0 0.2 1.6 1 0 0 1 1 1 0 RING-like domain Herpes_LMP1 PF05297.6 AEO66131.1 - 3.5 6.4 9.8 5.7 5.7 6.8 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) ATG22 PF11700.3 AEO66132.1 - 3.1e-201 669.0 14.9 3.6e-201 668.7 10.3 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 AEO66132.1 - 6.7e-05 21.7 45.5 0.042 12.5 5.5 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF3602 PF12223.3 AEO66133.1 - 3.8e-14 52.8 14.2 5.4e-13 49.1 4.9 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) FAA_hydrolase PF01557.13 AEO66134.1 - 2.5e-65 219.9 0.0 3.3e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Complex1_LYR PF05347.10 AEO66135.1 - 8e-18 63.9 2.6 9.9e-18 63.6 1.8 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AEO66135.1 - 4.3e-15 55.6 2.1 5e-15 55.4 1.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Vicilin_N PF04702.7 AEO66135.1 - 0.055 13.0 0.5 0.058 13.0 0.3 1.1 1 0 0 1 1 1 0 Vicilin N terminal region MutS_V PF00488.16 AEO66136.1 - 2.8e-77 259.3 0.0 1.2e-76 257.1 0.0 2.0 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AEO66136.1 - 4.8e-38 131.0 2.0 7.8e-38 130.3 1.4 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 AEO66136.1 - 2.9e-29 101.3 0.0 6.7e-29 100.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 AEO66136.1 - 1.7e-09 37.8 0.0 4.4e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 AEO66136.1 - 1.1e-06 28.6 0.0 2.8e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV Prenyltrans PF00432.16 AEO66138.1 - 1.4e-54 181.2 8.0 5.9e-12 44.9 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 AEO66138.1 - 1.1e-34 119.1 0.0 3.6e-14 53.1 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 AEO66138.1 - 7.7e-10 38.7 0.0 0.00061 19.7 0.0 2.5 1 1 1 2 2 2 2 Prenyltransferase-like RhoGAP PF00620.22 AEO66139.1 - 6.4e-29 100.5 0.0 1e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.7 AEO66140.1 - 3.5e-57 192.4 0.9 4e-57 192.2 0.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.4 AEO66141.1 - 5e-94 314.7 0.0 6e-94 314.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 AEO66141.1 - 0.0045 16.9 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain MCM PF00493.18 AEO66142.1 - 1.8e-132 441.1 0.0 3.7e-132 440.1 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AEO66142.1 - 4e-27 95.0 1.1 2e-26 92.8 0.4 2.4 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 AEO66142.1 - 2.5e-07 30.0 0.0 2e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AEO66142.1 - 1.2e-06 28.2 0.0 4.1e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 AEO66142.1 - 0.002 18.4 0.8 0.008 16.5 0.4 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AEO66142.1 - 0.032 13.8 0.0 0.11 12.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PBP1_TM PF14812.1 AEO66142.1 - 1.1 9.5 6.6 12 6.3 0.1 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA PF00004.24 AEO66143.1 - 5.7e-58 194.8 0.0 1.3e-43 148.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 AEO66143.1 - 4e-28 97.2 0.0 8.5e-28 96.2 0.0 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 AEO66143.1 - 1.9e-11 44.2 4.4 6.1e-06 26.3 0.1 4.2 2 2 0 3 3 3 2 AAA ATPase domain NACHT PF05729.7 AEO66143.1 - 2.8e-08 33.5 0.4 6.5e-05 22.6 0.0 3.5 3 1 0 3 3 3 1 NACHT domain AAA_2 PF07724.9 AEO66143.1 - 5.9e-08 32.8 0.0 0.002 18.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 AEO66143.1 - 2.9e-06 27.3 0.0 0.0014 18.6 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 AEO66143.1 - 4.9e-06 26.3 0.4 0.029 14.1 0.1 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 AEO66143.1 - 5.2e-06 26.1 0.0 0.031 14.0 0.0 3.5 2 0 0 2 2 2 2 Part of AAA domain Zeta_toxin PF06414.7 AEO66143.1 - 5.8e-06 25.5 0.0 0.017 14.2 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.1 AEO66143.1 - 6.2e-06 26.3 3.7 0.39 10.8 0.1 4.6 2 2 0 3 3 3 2 AAA domain AAA_17 PF13207.1 AEO66143.1 - 6.2e-06 27.0 0.3 0.12 13.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.7 AEO66143.1 - 6.3e-06 25.3 0.0 0.012 14.7 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 AEO66143.1 - 1.1e-05 25.3 0.5 0.3 10.9 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 AEO66143.1 - 1.1e-05 25.3 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 AEO66143.1 - 3e-05 23.5 0.1 0.066 12.6 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 AEO66143.1 - 3.6e-05 23.2 5.6 1.5 8.1 0.1 4.7 3 2 2 5 5 4 2 AAA domain AAA_18 PF13238.1 AEO66143.1 - 0.00038 20.7 0.2 0.24 11.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 AEO66143.1 - 0.00067 18.4 0.1 0.92 8.1 0.0 2.4 3 0 0 3 3 2 2 TIP49 C-terminus AAA_28 PF13521.1 AEO66143.1 - 0.00072 19.5 0.1 0.29 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 AEO66143.1 - 0.00072 18.6 0.2 0.81 8.6 0.0 2.5 1 1 1 2 2 2 2 KAP family P-loop domain RNA_helicase PF00910.17 AEO66143.1 - 0.00095 19.3 0.0 2.8 8.1 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Sigma54_activat PF00158.21 AEO66143.1 - 0.0012 18.3 0.0 0.076 12.4 0.0 2.7 3 0 0 3 3 3 1 Sigma-54 interaction domain NB-ARC PF00931.17 AEO66143.1 - 0.0013 17.6 0.1 0.31 9.8 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Mg_chelatase PF01078.16 AEO66143.1 - 0.0043 16.2 0.2 0.7 9.0 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 AEO66143.1 - 0.0067 16.1 0.0 0.18 11.5 0.0 2.6 2 0 0 2 2 2 1 NTPase KaiC PF06745.8 AEO66143.1 - 0.0071 15.4 0.0 1.7 7.7 0.0 2.4 2 0 0 2 2 2 1 KaiC ABC_tran PF00005.22 AEO66143.1 - 0.0087 16.3 0.1 5.3 7.3 0.0 2.9 3 0 0 3 3 2 0 ABC transporter UPF0079 PF02367.12 AEO66143.1 - 0.01 15.4 0.0 0.23 11.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 AEO66143.1 - 0.026 14.0 0.1 0.22 11.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 AEO66143.1 - 0.033 13.7 0.0 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 AEO66143.1 - 0.037 13.5 0.7 7 6.1 0.2 2.9 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.4 AEO66143.1 - 0.042 12.8 0.0 7.1 5.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.8 AEO66143.1 - 0.049 12.5 0.0 0.83 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 AEO66143.1 - 0.068 12.8 0.0 13 5.3 0.0 3.2 2 1 1 3 3 3 0 Archaeal ATPase SKI PF01202.17 AEO66143.1 - 0.1 12.4 0.2 5.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase T2SE PF00437.15 AEO66143.1 - 0.13 11.1 0.1 0.73 8.6 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein CobU PF02283.11 AEO66143.1 - 0.16 11.3 0.0 0.16 11.3 0.0 2.0 3 0 0 3 3 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase APS_kinase PF01583.15 AEO66143.1 - 0.16 11.5 0.3 0.82 9.3 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase Cytidylate_kin2 PF13189.1 AEO66143.1 - 0.21 11.4 0.0 2.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family KTI12 PF08433.5 AEO66143.1 - 0.23 10.6 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PduV-EutP PF10662.4 AEO66143.1 - 0.33 10.4 0.2 5.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Parvo_NS1 PF01057.12 AEO66143.1 - 0.35 9.6 0.0 24 3.6 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Ank_2 PF12796.2 AEO66144.1 - 1.1e-06 28.9 0.0 4.1e-06 27.0 0.0 2.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) CBM_11 PF03425.8 AEO66144.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) Ank_5 PF13857.1 AEO66144.1 - 0.023 14.9 0.3 0.72 10.1 0.1 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.25 AEO66144.1 - 0.04 13.7 0.1 1.2 9.0 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat VTC PF09359.5 AEO66145.1 - 6.3e-102 340.4 0.0 9.9e-102 339.7 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 AEO66145.1 - 6e-30 104.9 3.0 1.7e-16 60.8 0.2 2.6 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 AEO66145.1 - 1.3e-11 44.4 6.4 2e-11 43.9 3.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TrmB PF01978.14 AEO66145.1 - 0.0031 17.1 0.3 0.032 13.9 0.1 2.5 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.1 AEO66145.1 - 0.023 14.8 0.5 0.27 11.4 0.1 2.8 2 1 1 3 3 3 0 Winged helix-turn helix Fe_dep_repress PF01325.14 AEO66145.1 - 0.063 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Host_attach PF10116.4 AEO66145.1 - 4.9 7.3 8.2 0.42 10.8 1.6 2.2 2 0 0 2 2 2 0 Protein required for attachment to host cells Cys_Met_Meta_PP PF01053.15 AEO66146.1 - 1.5e-26 92.6 0.0 2.1e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 AEO66146.1 - 0.00046 19.2 0.0 0.00069 18.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AEO66146.1 - 0.1 11.7 0.0 1.1 8.3 0.0 2.1 1 1 0 1 1 1 0 Beta-eliminating lyase Hexokinase_2 PF03727.11 AEO66147.1 - 6.3e-87 290.7 0.0 8.7e-87 290.3 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 AEO66147.1 - 1.8e-74 249.5 0.0 8.1e-73 244.1 0.0 2.1 2 0 0 2 2 2 2 Hexokinase Ribophorin_I PF04597.9 AEO66148.1 - 4.4e-155 516.4 0.0 5.1e-155 516.2 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Pil1 PF13805.1 AEO66149.1 - 3.5e-109 364.1 4.1 4.4e-109 363.8 2.9 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 MCM PF00493.18 AEO66150.1 - 1.6e-140 467.6 0.0 2.1e-140 467.2 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AEO66150.1 - 1.1e-26 93.6 0.0 4.5e-26 91.7 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 AEO66150.1 - 1.7e-06 27.8 0.1 8.7e-06 25.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 AEO66150.1 - 8.6e-06 25.0 0.0 0.00035 19.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AEO66150.1 - 0.0023 17.5 0.0 0.009 15.6 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) EAP30 PF04157.11 AEO66150.1 - 0.069 12.2 0.8 0.18 10.9 0.2 2.0 2 0 0 2 2 2 0 EAP30/Vps36 family Elf1 PF05129.8 AEO66150.1 - 0.15 11.7 2.3 0.24 11.1 0.8 1.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Clat_adaptor_s PF01217.15 AEO66151.1 - 8.3e-15 54.7 0.2 9.9e-14 51.2 0.2 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain zf-C4H2 PF10146.4 AEO66151.1 - 0.021 14.8 0.0 0.028 14.4 0.0 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Sua5_yciO_yrdC PF01300.13 AEO66152.1 - 3.8e-50 169.5 0.0 5.1e-49 165.9 0.0 2.0 1 1 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 AEO66152.1 - 2.5e-26 92.2 0.0 4.4e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Pkinase PF00069.20 AEO66153.1 - 2.9e-56 190.5 0.0 4.1e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO66153.1 - 4.9e-42 143.8 0.0 7.5e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO66153.1 - 0.012 14.5 0.0 0.037 12.9 0.0 1.8 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 AEO66153.1 - 0.045 12.8 0.0 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ECH PF00378.15 AEO66153.1 - 0.15 11.1 0.1 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family FAD_binding_3 PF01494.14 AEO66155.1 - 2e-21 76.4 0.4 2.2e-19 69.7 0.3 2.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO66155.1 - 2.4e-06 26.7 0.0 0.026 13.4 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 AEO66155.1 - 0.00022 20.2 0.1 0.0044 16.0 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein SE PF08491.5 AEO66155.1 - 0.0005 18.9 0.0 0.00078 18.3 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.1 AEO66155.1 - 0.0041 16.9 0.0 0.0077 16.0 0.0 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 AEO66155.1 - 0.021 14.7 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO66155.1 - 0.049 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 AEO66155.1 - 0.055 12.0 0.0 2 6.9 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase K_oxygenase PF13434.1 AEO66155.1 - 0.065 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 AEO66155.1 - 0.073 12.1 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Complex1_49kDa PF00346.14 AEO66157.1 - 9.4e-132 438.0 0.0 1.2e-131 437.6 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit RNA_pol_A_bac PF01000.21 AEO66158.1 - 1.6e-26 92.6 0.0 4.3e-26 91.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 AEO66158.1 - 3.2e-13 48.5 0.0 4.1e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.16 AEO66159.1 - 7.8e-39 132.6 0.4 1.4e-38 131.7 0.1 1.5 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 AEO66159.1 - 2.1e-29 101.1 0.0 3.5e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 AEO66159.1 - 4e-25 87.1 0.1 7.1e-25 86.3 0.1 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 AEO66159.1 - 9e-16 56.9 1.9 2.1e-15 55.8 1.3 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 AEO66159.1 - 0.00028 21.0 0.1 0.00053 20.0 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.1 AEO66159.1 - 0.00065 19.7 0.0 0.01 15.8 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 AEO66159.1 - 0.024 14.9 0.0 0.058 13.6 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding MoeZ_MoeB PF05237.8 AEO66159.1 - 0.095 12.3 0.1 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 MoeZ/MoeB domain DAO PF01266.19 AEO66159.1 - 0.13 11.1 0.0 0.27 10.0 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.13 AEO66159.1 - 0.14 12.1 0.1 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.22 AEO66159.1 - 0.15 12.4 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-IS66 PF13005.2 AEO66159.1 - 0.19 11.7 1.5 0.48 10.4 0.0 2.4 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Ecm33 PF12454.3 AEO66159.1 - 0.34 10.8 2.4 0.74 9.7 1.7 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Telomere_reg-2 PF10193.4 AEO66161.1 - 9.1e-40 135.4 0.0 1.7e-39 134.6 0.0 1.5 1 0 0 1 1 1 1 Telomere length regulation protein COX17 PF05051.8 AEO66162.1 - 1.8e-20 72.6 6.6 2.1e-20 72.4 4.6 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) GPW_gp25 PF04965.9 AEO66163.1 - 0.27 10.8 2.0 9.5 5.8 0.1 2.3 1 1 1 2 2 2 0 Gene 25-like lysozyme DIT1_PvcA PF05141.7 AEO66163.1 - 0.29 10.4 3.7 0.36 10.0 2.6 1.1 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein SlyX PF04102.7 AEO66163.1 - 0.75 10.2 2.8 0.46 10.8 0.2 2.0 2 1 0 2 2 2 0 SlyX G-patch PF01585.18 AEO66164.1 - 7.8e-06 25.5 0.0 7.4e-05 22.4 0.0 2.8 2 1 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 AEO66164.1 - 0.00027 20.7 0.2 0.00027 20.7 0.1 4.2 4 1 0 4 4 4 1 DExH-box splicing factor binding site Med19 PF10278.4 AEO66164.1 - 0.2 11.3 39.2 0.2 11.3 8.7 2.9 3 0 0 3 3 3 0 Mediator of RNA pol II transcription subunit 19 vMSA PF00695.14 AEO66166.1 - 0.14 11.3 0.7 0.24 10.5 0.5 1.4 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Fungal_trans PF04082.13 AEO66167.1 - 5.2e-08 32.0 0.0 8.4e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO66167.1 - 5e-05 23.1 10.8 9.5e-05 22.2 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGAP PF00620.22 AEO66168.1 - 1.1e-44 151.6 0.4 7.7e-44 148.9 0.1 2.3 3 0 0 3 3 3 1 RhoGAP domain PH PF00169.24 AEO66168.1 - 6.4e-11 42.3 0.0 1.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 AEO66168.1 - 3.1e-06 27.4 0.0 7.3e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 AEO66168.1 - 0.0087 16.1 0.2 0.072 13.1 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain DUF3450 PF11932.3 AEO66168.1 - 0.027 13.7 3.9 0.053 12.7 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PX PF00787.19 AEO66168.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 PX domain Totivirus_coat PF05518.6 AEO66171.1 - 5.8 4.6 7.7 7.4 4.2 5.3 1.1 1 0 0 1 1 1 0 Totivirus coat protein PITH PF06201.8 AEO66174.1 - 9.1e-44 148.8 0.0 1.3e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 AEO66174.1 - 1.7e-24 85.4 0.0 3.3e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AEO66174.1 - 2.2e-07 30.8 0.1 3.3e-06 27.1 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 AEO66174.1 - 2.3e-06 27.7 0.1 9e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 AEO66174.1 - 0.0014 18.1 0.3 0.015 14.8 0.2 2.1 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 AEO66174.1 - 0.0024 17.5 0.1 0.024 14.2 0.1 2.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 AEO66174.1 - 0.0079 16.1 0.1 0.023 14.7 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 AEO66174.1 - 0.0087 15.6 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.11 AEO66174.1 - 0.06 12.8 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 HyaE PF07449.6 AEO66174.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE MFS_1 PF07690.11 AEO66176.1 - 8.5e-26 90.4 39.6 8.5e-26 90.4 27.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO66176.1 - 1.3e-13 50.3 5.8 1.3e-13 50.3 4.0 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 AEO66176.1 - 5.1e-05 21.6 0.7 8.4e-05 20.9 0.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Corona_NS4 PF03905.8 AEO66176.1 - 0.031 14.0 0.0 0.097 12.4 0.0 1.8 1 0 0 1 1 1 0 Coronavirus non-structural protein NS4 PRA1 PF03208.14 AEO66177.1 - 1.5e-37 128.2 0.9 1.8e-37 128.0 0.6 1.1 1 0 0 1 1 1 1 PRA1 family protein Ni_hydr_CYTB PF01292.15 AEO66177.1 - 0.023 14.0 0.2 0.028 13.8 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4282 PF14110.1 AEO66177.1 - 1.8 8.8 7.2 0.33 11.1 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Zip PF02535.17 AEO66178.1 - 1.8 7.4 4.2 2.7 6.9 2.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter YbjQ_1 PF01906.12 AEO66181.1 - 5.5e-28 97.4 0.3 6.3e-28 97.2 0.2 1.0 1 0 0 1 1 1 1 Putative heavy-metal-binding DPPIV_N PF00930.16 AEO66182.1 - 3e-109 364.8 0.2 4e-109 364.4 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 AEO66182.1 - 5e-54 182.7 1.8 8.7e-54 181.9 1.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO66182.1 - 2e-08 34.0 0.6 1e-07 31.7 0.1 2.5 3 0 0 3 3 3 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 AEO66182.1 - 1.1e-06 28.2 1.6 3.7e-05 23.2 0.7 2.4 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 AEO66182.1 - 6.6e-06 26.1 0.1 0.00014 21.8 0.1 2.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 AEO66182.1 - 0.032 13.5 0.6 0.46 9.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family PAF-AH_p_II PF03403.8 AEO66182.1 - 0.055 11.7 0.0 0.086 11.1 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II ATP-synt_ab PF00006.20 AEO66186.1 - 1.5e-70 237.0 0.0 2.6e-70 236.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AEO66186.1 - 7.3e-27 94.0 0.3 3e-26 92.0 0.2 2.1 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AEO66186.1 - 9.8e-16 57.7 2.8 3.3e-15 56.0 2.0 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 AEO66186.1 - 0.0052 16.6 1.0 0.013 15.3 0.5 1.9 2 0 0 2 2 2 1 HAS barrel domain Carb_kinase PF01256.12 AEO66187.1 - 1.9e-54 184.5 0.1 2.4e-54 184.1 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 AEO66187.1 - 0.00052 19.2 0.0 0.0008 18.6 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 AEO66187.1 - 0.0051 16.0 0.0 0.0099 15.0 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 AEO66187.1 - 0.053 12.6 0.0 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 pfkB family carbohydrate kinase Surfac_D-trimer PF09006.6 AEO66188.1 - 0.085 12.5 0.2 0.24 11.1 0.1 1.7 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Ribosomal_L5_C PF00673.16 AEO66189.1 - 9.9e-23 79.6 0.0 1.4e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 AEO66189.1 - 2.5e-21 75.2 0.1 7e-21 73.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 AEO66190.1 - 7.3e-18 63.8 0.0 1e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.8 AEO66191.1 - 3.1e-34 117.4 0.1 3.8e-34 117.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MtN3_slv PF03083.11 AEO66191.1 - 0.033 14.0 0.2 0.045 13.6 0.2 1.3 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange CPSase_L_D2 PF02786.12 AEO66192.1 - 2.9e-81 271.7 0.2 4.6e-81 271.1 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 AEO66192.1 - 6.1e-67 224.8 0.0 1.1e-66 224.0 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 AEO66192.1 - 1.9e-35 121.3 0.0 3.8e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 AEO66192.1 - 2.5e-33 114.2 0.0 6.7e-33 112.8 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 AEO66192.1 - 6.5e-26 91.4 0.0 1.3e-25 90.4 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 AEO66192.1 - 1.3e-19 70.6 0.1 3.3e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 AEO66192.1 - 1.1e-18 66.6 0.8 1.1e-18 66.6 0.5 2.0 2 0 0 2 2 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 AEO66192.1 - 2.7e-16 59.2 0.0 2.5e-15 56.0 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 AEO66192.1 - 1.1e-10 41.2 0.0 2.1e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 AEO66192.1 - 1.8e-09 37.1 1.2 6.1e-06 25.7 0.0 3.1 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.17 AEO66192.1 - 3.6e-08 32.9 0.0 7.2e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 AEO66192.1 - 7.8e-07 28.7 0.0 3.9e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 AEO66192.1 - 2e-05 24.5 0.0 4.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 AEO66192.1 - 0.00032 20.1 0.1 0.0086 15.4 0.0 2.4 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 AEO66192.1 - 0.0018 18.5 0.1 6.1 7.2 0.0 3.4 3 0 0 3 3 3 1 HlyD family secretion protein HlyD_2 PF12700.2 AEO66192.1 - 0.016 14.3 0.0 0.78 8.8 0.0 2.2 1 1 1 2 2 2 0 HlyD family secretion protein DUF2118 PF09891.4 AEO66192.1 - 0.018 14.7 0.1 0.064 12.9 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) GARS_A PF01071.14 AEO66192.1 - 0.026 14.0 0.0 0.078 12.5 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Nitroreductase PF00881.19 AEO66192.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Nitroreductase family Clathrin PF00637.15 AEO66194.1 - 1.6e-201 659.9 39.9 7.9e-35 119.5 1.0 7.7 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 AEO66194.1 - 1.2e-33 114.8 0.7 4.5e-33 112.9 0.5 2.1 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 AEO66194.1 - 1.2e-30 103.6 0.1 4.5e-06 26.5 0.0 7.6 7 0 0 7 7 7 7 Clathrin propeller repeat TPR_7 PF13176.1 AEO66194.1 - 0.00016 21.1 6.1 4.8 7.2 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 AEO66194.1 - 0.033 14.8 19.1 11 6.9 0.1 9.7 10 1 2 12 12 12 0 Tetratricopeptide repeat Ank_3 PF13606.1 AEO66194.1 - 0.044 14.0 0.2 0.94 9.9 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeat Clathrin-link PF09268.5 AEO66194.1 - 2.8 7.0 9.7 3 6.9 0.2 3.1 3 0 0 3 3 3 0 Clathrin, heavy-chain linker Nol1_Nop2_Fmu PF01189.12 AEO66195.1 - 1.4e-100 336.3 0.0 2.2e-100 335.6 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 AEO66195.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 AEO66195.1 - 0.028 14.4 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 AEO66195.1 - 0.032 14.7 0.2 0.24 12.0 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain DUF1640 PF07798.6 AEO66196.1 - 7.5e-66 221.5 7.6 8.8e-66 221.2 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Syntaxin PF00804.20 AEO66196.1 - 0.014 15.4 4.8 0.014 15.4 3.3 2.3 1 1 1 2 2 2 0 Syntaxin CLAMP PF14769.1 AEO66196.1 - 0.1 12.7 0.1 0.2 11.7 0.1 1.6 1 1 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Exonuc_V_gamma PF04257.9 AEO66200.1 - 0.0096 13.9 0.3 0.0096 13.9 0.2 1.2 1 0 0 1 1 1 1 Exodeoxyribonuclease V, gamma subunit RVT_1 PF00078.22 AEO66200.1 - 0.14 11.4 0.6 0.18 11.1 0.4 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cullin PF00888.17 AEO66201.1 - 1.8e-126 423.0 0.3 2.5e-126 422.6 0.2 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 AEO66201.1 - 6.3e-27 93.1 1.4 1.3e-26 92.1 0.2 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain zf-DNL PF05180.7 AEO66202.1 - 1.1e-26 92.2 0.0 1.5e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 AEO66202.1 - 0.023 14.1 0.3 0.04 13.4 0.2 1.3 1 0 0 1 1 1 0 CSL zinc finger HypA PF01155.14 AEO66202.1 - 0.04 13.6 0.6 0.22 11.1 0.6 1.8 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-GRF PF06839.7 AEO66202.1 - 0.33 10.8 2.4 0.58 10.1 1.7 1.4 1 0 0 1 1 1 0 GRF zinc finger DRIM PF07539.7 AEO66203.1 - 5.6e-43 145.7 0.1 2.8e-42 143.4 0.0 2.3 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.17 AEO66203.1 - 9e-10 37.8 3.6 1.2 9.4 0.0 8.1 8 0 0 8 8 8 3 HEAT repeat CwfJ_C_1 PF04677.10 AEO66204.1 - 3e-26 91.4 0.0 8.6e-26 89.9 0.0 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 AEO66204.1 - 1.1e-23 83.5 0.1 2.7e-23 82.3 0.1 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Rhodanese PF00581.15 AEO66205.1 - 3.2e-12 46.7 0.0 6.3e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DNA_pol_phi PF04931.8 AEO66206.1 - 2.3e-45 154.6 25.8 4e-36 124.1 17.9 3.1 2 1 0 2 2 2 2 DNA polymerase phi Uteroglobin PF01099.12 AEO66206.1 - 0.059 13.1 0.0 0.24 11.2 0.0 2.1 1 0 0 1 1 1 0 Uteroglobin family Proteasome PF00227.21 AEO66207.1 - 4.2e-45 153.3 0.3 3.4e-30 104.7 0.0 2.8 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.4 AEO66207.1 - 1.2e-11 43.7 0.9 1.6e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF2630 PF10944.3 AEO66208.1 - 0.043 13.9 0.7 0.12 12.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) DnaJ PF00226.26 AEO66210.1 - 1.8e-19 69.2 1.0 2.9e-19 68.5 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain MgtE_N PF03448.12 AEO66210.1 - 0.06 13.6 0.1 1.6 9.1 0.0 2.2 2 0 0 2 2 2 0 MgtE intracellular N domain SseB_C PF14581.1 AEO66210.1 - 0.061 13.1 0.0 5.8 6.8 0.0 2.2 2 0 0 2 2 2 0 SseB protein C-terminal domain DUF456 PF04306.8 AEO66210.1 - 0.18 11.8 4.3 0.39 10.7 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DnaJ PF00226.26 AEO66211.1 - 1.3e-11 44.0 0.8 2.3e-11 43.2 0.6 1.5 1 1 0 1 1 1 1 DnaJ domain RNA_ligase PF09414.5 AEO66214.1 - 4.9e-26 91.6 0.0 7e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 RNA ligase S1-P1_nuclease PF02265.11 AEO66216.1 - 3e-74 249.8 0.0 3.4e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Zn_clus PF00172.13 AEO66218.1 - 1.2e-07 31.5 6.7 2.3e-07 30.5 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO66218.1 - 0.0011 17.7 0.9 0.0015 17.1 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TrbC PF04956.8 AEO66219.1 - 0.15 12.1 2.1 0.33 11.0 1.1 1.8 1 1 1 2 2 2 0 TrbC/VIRB2 family hDGE_amylase PF14701.1 AEO66220.1 - 2.9e-176 586.5 0.0 3.7e-176 586.1 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 AEO66220.1 - 1.2e-112 376.3 0.0 2.9e-112 375.0 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 AEO66220.1 - 2.1e-87 292.6 0.0 6.2e-87 291.0 0.0 1.8 2 0 0 2 2 2 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 AEO66220.1 - 6.7e-27 93.1 0.0 1.5e-26 91.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 AEO66220.1 - 0.00019 20.9 0.0 0.68 9.2 0.0 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain RVT_1 PF00078.22 AEO66221.1 - 0.00034 20.0 0.0 0.00049 19.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Prothymosin PF03247.9 AEO66223.1 - 0.037 14.1 9.2 0.048 13.8 6.4 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family CENP-B_dimeris PF09026.5 AEO66223.1 - 0.12 12.5 3.4 0.19 12.0 2.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DTHCT PF08070.6 AEO66223.1 - 0.22 12.2 5.5 0.18 12.5 3.0 1.4 1 1 0 1 1 1 0 DTHCT (NUC029) region Spore_coat_CotO PF14153.1 AEO66223.1 - 0.32 10.3 2.7 0.36 10.2 1.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Nucleoplasmin PF03066.10 AEO66223.1 - 0.48 9.9 5.7 0.54 9.7 4.0 1.1 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 AEO66223.1 - 0.93 9.0 7.0 0.97 9.0 4.8 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 AEO66223.1 - 1.1 9.6 8.8 1.6 9.0 6.1 1.5 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-CCHC PF00098.18 AEO66224.1 - 1.3e-13 50.1 15.4 5.5e-05 22.8 0.2 3.4 3 0 0 3 3 3 3 Zinc knuckle Retrotrans_gag PF03732.12 AEO66224.1 - 2.4e-07 30.7 0.0 4.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_4 PF14392.1 AEO66224.1 - 4.3e-05 23.0 12.4 0.11 12.1 0.3 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.1 AEO66224.1 - 0.15 11.7 7.7 0.49 10.1 0.6 3.3 2 1 1 3 3 3 0 Zinc knuckle UBN2 PF14223.1 AEO66224.1 - 0.2 11.4 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RNA_pol_N PF01194.12 AEO66224.1 - 0.39 10.7 4.8 0.34 10.9 0.7 2.4 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit zf-CCHC_2 PF13696.1 AEO66224.1 - 1.7 8.2 13.7 0.94 9.0 1.3 3.7 2 1 1 3 3 3 0 Zinc knuckle ADH_N PF08240.7 AEO66225.1 - 1.1e-10 41.2 0.0 2.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO66225.1 - 1.5e-06 27.8 0.5 3.1e-06 26.7 0.4 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 AEO66226.1 - 4.2e-09 36.5 0.0 4.3e-08 33.2 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO66226.1 - 1.7e-06 27.8 0.0 2.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 AEO66226.1 - 0.089 11.7 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Fungal_trans_2 PF11951.3 AEO66227.1 - 3.5e-06 25.8 0.4 6.1e-06 25.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3328 PF11807.3 AEO66229.1 - 1.7e-17 63.8 0.7 5e-17 62.3 0.3 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) Chitin_bind_1 PF00187.14 AEO66230.1 - 1.5e-09 37.6 14.9 1.5e-09 37.6 10.3 2.6 2 1 0 2 2 2 1 Chitin recognition protein TEX19 PF15553.1 AEO66231.1 - 0.099 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 SH3_9 PF14604.1 AEO66232.1 - 3.5e-14 52.1 3.5 3.2e-09 36.2 0.2 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 AEO66232.1 - 4.4e-05 22.8 0.2 4.4e-05 22.8 0.2 1.9 2 0 0 2 2 2 1 Variant SH3 domain KGG PF10685.4 AEO66233.1 - 2.8e-28 97.2 20.5 2.4e-12 46.4 1.5 3.2 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif Peptidase_S8 PF00082.17 AEO66235.1 - 1.2e-25 90.2 0.0 1.9e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Dicty_CAR PF05462.6 AEO66238.1 - 3.9e-11 42.3 10.9 3.9e-11 42.3 7.6 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 AEO66238.1 - 9.6e-10 38.3 11.1 9.6e-10 38.3 7.7 1.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 AEO66238.1 - 4.1e-09 35.9 0.7 6.8e-09 35.2 0.5 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 AEO66238.1 - 0.19 10.8 12.2 0.3 10.2 8.4 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Mannitol_dh_C PF08125.8 AEO66239.1 - 1e-45 155.8 0.1 1.3e-45 155.4 0.1 1.1 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 AEO66239.1 - 3.7e-21 75.6 0.4 1.9e-20 73.3 0.0 2.2 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.9 AEO66239.1 - 0.00023 20.5 0.6 0.00057 19.3 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 AEO66239.1 - 0.0019 17.8 0.7 0.007 16.0 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2293 PF10056.4 AEO66239.1 - 0.077 12.9 1.3 0.22 11.5 0.9 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) NAD_Gly3P_dh_N PF01210.18 AEO66239.1 - 0.14 11.8 0.4 0.59 9.8 0.1 2.3 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Coatomer_WDAD PF04053.9 AEO66240.1 - 2.4e-174 580.3 0.0 1.6e-172 574.2 0.0 2.1 2 0 0 2 2 2 2 Coatomer WD associated region WD40 PF00400.27 AEO66240.1 - 1.4e-46 154.7 7.3 9.5e-10 37.9 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 AEO66240.1 - 1e-06 27.1 3.1 0.0074 14.4 0.0 4.7 2 1 3 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 AEO66240.1 - 0.00015 21.5 0.0 0.21 11.3 0.0 3.6 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region YmzC PF14157.1 AEO66240.1 - 0.023 14.5 0.2 10 6.0 0.1 3.9 5 0 0 5 5 5 0 YmzC-like protein Apc4_WD40 PF12894.2 AEO66240.1 - 0.12 11.8 0.0 4.1 6.9 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain CRAL_TRIO PF00650.15 AEO66241.1 - 5.5e-24 84.4 0.0 8.7e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AEO66241.1 - 1.7e-10 40.8 0.1 3.9e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Acid_PPase PF12689.2 AEO66242.1 - 2.5e-52 176.9 0.0 3e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 AEO66242.1 - 0.003 17.7 0.1 0.23 11.6 0.0 2.7 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Glyoxalase PF00903.20 AEO66243.1 - 1.1e-07 31.8 7.6 1.6e-05 24.8 2.7 2.8 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FMN_red PF03358.10 AEO66244.1 - 1.7e-28 99.0 0.0 2.1e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 AEO66244.1 - 6.3e-08 32.3 0.3 6.2e-07 29.1 0.2 1.9 1 1 1 2 2 2 1 Flavodoxin-like fold DUF4109 PF13397.1 AEO66244.1 - 0.14 12.5 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4109) ketoacyl-synt PF00109.21 AEO66245.1 - 9.6e-72 241.4 0.1 3e-71 239.8 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 AEO66245.1 - 6.3e-54 183.4 0.6 1.5e-51 175.6 0.0 2.3 2 0 0 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.17 AEO66245.1 - 5.9e-33 113.2 2.9 6.9e-33 113.0 0.4 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 AEO66245.1 - 4.6e-12 46.0 0.2 3.6e-11 43.1 0.1 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 AEO66245.1 - 0.00046 19.2 0.0 0.00088 18.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain TALPID3 PF15324.1 AEO66245.1 - 4.2 4.5 7.2 6.5 3.9 5.0 1.2 1 0 0 1 1 1 0 Hedgehog signalling target DEC-1_N PF04625.8 AEO66245.1 - 9.2 4.8 18.9 17 3.9 13.1 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region AflR PF08493.5 AEO66247.1 - 9.9e-12 44.4 0.0 9.9e-12 44.4 0.0 2.8 1 1 0 3 3 3 1 Aflatoxin regulatory protein Zn_clus PF00172.13 AEO66247.1 - 4.1e-08 32.9 12.4 7.6e-08 32.1 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4243 PF14027.1 AEO66249.1 - 1.8e-82 277.4 0.1 2.4e-82 277.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) NAD_binding_10 PF13460.1 AEO66250.1 - 1.6e-15 57.5 0.2 3.4e-15 56.5 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 AEO66250.1 - 3.1e-05 23.3 0.0 4.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 AEO66250.1 - 0.0012 18.3 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO66250.1 - 0.038 12.9 0.0 0.11 11.4 0.0 1.8 1 1 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.10 AEO66250.1 - 0.052 12.4 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 AEO66250.1 - 0.085 13.1 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 AEO66250.1 - 0.11 11.2 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Lactamase_B PF00753.22 AEO66251.1 - 3.3e-27 95.3 3.0 5.4e-27 94.7 2.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AEO66251.1 - 1.4e-07 31.2 0.2 2.3e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AEO66251.1 - 0.00014 21.5 0.1 0.00023 20.9 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF1772 PF08592.6 AEO66252.1 - 2.7e-20 72.5 1.9 2.7e-20 72.5 1.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Cytochrom_B_N PF00033.14 AEO66252.1 - 0.37 10.1 7.8 0.025 13.9 0.9 2.0 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Cu-oxidase_3 PF07732.10 AEO66253.1 - 1.2e-39 134.7 6.9 1.8e-37 127.6 3.9 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 AEO66253.1 - 6.9e-39 132.5 6.3 3.2e-36 123.8 0.2 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 AEO66253.1 - 1.4e-31 109.5 0.0 3e-30 105.2 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase AA_permease PF00324.16 AEO66254.1 - 4.1e-123 411.2 41.1 5.1e-123 410.9 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO66254.1 - 3e-33 114.9 45.7 3.6e-33 114.7 31.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3129 PF11327.3 AEO66255.1 - 4.9e-68 228.5 11.4 5.9e-68 228.3 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) PBP PF01161.15 AEO66257.1 - 2e-21 76.3 0.0 2.3e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FAP PF07174.6 AEO66257.1 - 0.0093 15.3 2.8 0.012 14.9 2.0 1.1 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) Pectinesterase PF01095.14 AEO66258.1 - 6.9e-51 172.5 7.3 9.4e-51 172.1 5.0 1.0 1 0 0 1 1 1 1 Pectinesterase Glyco_hydro_2 PF00703.16 AEO66261.1 - 2e-07 31.4 0.0 4.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4217 PF13959.1 AEO66261.1 - 0.015 14.7 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) Asp PF00026.18 AEO66262.1 - 3.8e-80 269.4 6.8 4.5e-80 269.2 4.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO66262.1 - 1.2e-08 35.0 0.6 1e-07 32.0 0.1 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO66262.1 - 2.3e-05 24.7 1.1 0.37 11.3 0.2 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 AEO66262.1 - 0.02 14.4 0.0 0.053 13.0 0.0 1.9 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Glyco_hydro_16 PF00722.16 AEO66263.1 - 3.3e-15 55.8 2.5 1.1e-14 54.0 1.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 AEO66263.1 - 5.2e-06 24.9 6.6 0.0022 16.2 0.3 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Abhydrolase_6 PF12697.2 AEO66264.1 - 7.2e-20 71.8 0.4 7.2e-20 71.8 0.3 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO66264.1 - 5.1e-09 36.0 0.1 0.0026 17.4 0.0 2.7 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO66264.1 - 2.8e-07 30.3 0.0 7.7e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3808 PF10300.4 AEO66265.1 - 3e-125 418.4 0.0 3.8e-125 418.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_10 PF13374.1 AEO66265.1 - 0.077 12.9 2.7 0.43 10.5 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 AEO66265.1 - 0.34 11.2 6.0 1.6 9.1 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DSS1_SEM1 PF05160.8 AEO66266.1 - 1e-25 89.2 13.1 1e-25 89.2 9.1 1.4 2 0 0 2 2 2 1 DSS1/SEM1 family PGK PF00162.14 AEO66267.1 - 4.3e-153 509.4 0.3 4.9e-153 509.2 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.6 AEO66267.1 - 0.07 12.5 0.4 7.5 5.9 0.1 3.2 3 1 1 4 4 4 0 Propionate catabolism activator FIVAR PF07554.8 AEO66267.1 - 0.32 11.2 6.0 2.2 8.6 0.0 3.7 4 0 0 4 4 4 0 Uncharacterised Sugar-binding Domain Mpv17_PMP22 PF04117.7 AEO66268.1 - 2.5e-23 81.4 0.2 7.1e-23 80.0 0.1 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF746 PF05344.6 AEO66268.1 - 0.099 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Mpv17_PMP22 PF04117.7 AEO66271.1 - 9.5e-17 60.3 0.5 9.5e-17 60.3 0.4 2.3 1 1 1 2 2 2 1 Mpv17 / PMP22 family DHO_dh PF01180.16 AEO66272.1 - 1.2e-65 221.4 0.0 4.9e-65 219.3 0.0 1.8 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 AEO66272.1 - 0.00018 20.8 0.7 0.24 10.6 0.1 2.2 2 0 0 2 2 2 2 PcrB family Cleaved_Adhesin PF07675.6 AEO66272.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Cleaved Adhesin Domain FMN_dh PF01070.13 AEO66272.1 - 0.15 10.9 1.8 0.2 10.4 0.2 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Lipase_GDSL_2 PF13472.1 AEO66272.1 - 0.23 11.6 3.7 1.7 8.7 0.2 3.1 2 1 1 3 3 3 0 GDSL-like Lipase/Acylhydrolase family PsbT PF01405.12 AEO66273.1 - 2.1 7.9 11.9 5.2 6.7 1.2 3.0 2 0 0 2 2 2 0 Photosystem II reaction centre T protein Glyco_hydro_61 PF03443.9 AEO66274.1 - 3.9e-70 236.0 0.1 4.7e-70 235.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 FAD_binding_3 PF01494.14 AEO66275.1 - 9.8e-13 47.8 0.5 3.9e-06 26.1 0.3 2.7 2 1 1 3 3 3 2 FAD binding domain RVT_1 PF00078.22 AEO66276.1 - 0.0001 21.7 0.1 0.00015 21.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pox_Ag35 PF03286.9 AEO66277.1 - 0.0047 16.4 8.7 0.0068 15.9 6.0 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein PBP_sp32 PF07222.7 AEO66277.1 - 0.056 12.6 4.0 0.074 12.2 2.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF3246 PF11596.3 AEO66277.1 - 0.058 12.6 0.3 0.068 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Glypican PF01153.14 AEO66277.1 - 0.068 11.7 0.7 0.082 11.5 0.5 1.1 1 0 0 1 1 1 0 Glypican Na_trans_assoc PF06512.8 AEO66277.1 - 0.09 12.7 3.1 0.1 12.5 2.2 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated PBP1_TM PF14812.1 AEO66277.1 - 0.1 12.9 22.6 0.094 13.0 3.3 2.3 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 AEO66277.1 - 0.16 9.8 13.4 0.19 9.6 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 AEO66277.1 - 0.24 10.3 12.9 0.32 9.9 8.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TFIIF_alpha PF05793.7 AEO66277.1 - 0.29 9.4 17.6 0.37 9.1 12.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PGA2 PF07543.7 AEO66277.1 - 0.45 10.3 12.0 0.75 9.5 8.3 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF2201_N PF13203.1 AEO66277.1 - 0.83 8.7 6.2 1.2 8.2 4.3 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain Tom22 PF04281.8 AEO66277.1 - 0.91 9.0 6.6 0.28 10.6 0.7 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Daxx PF03344.10 AEO66277.1 - 0.94 7.8 10.1 1.3 7.3 7.0 1.3 1 0 0 1 1 1 0 Daxx Family AF1Q PF15017.1 AEO66277.1 - 1 9.3 8.6 9.5 6.2 0.1 2.2 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator RNase_H2_suC PF08615.6 AEO66277.1 - 1.1 9.0 5.0 26 4.6 3.5 2.0 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) eIF3_subunit PF08597.5 AEO66277.1 - 1.7 8.1 19.9 2.4 7.6 13.8 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1510 PF07423.6 AEO66277.1 - 2.1 7.6 12.8 2.6 7.3 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2151 PF10221.4 AEO66277.1 - 3.5 5.6 5.9 3.9 5.5 4.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator ANAPC15 PF15243.1 AEO66277.1 - 4.4 7.4 15.1 5.7 7.0 5.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 eIF-3c_N PF05470.7 AEO66277.1 - 5.1 5.0 9.1 6.1 4.8 6.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus COesterase PF00135.23 AEO66278.1 - 3.3e-82 276.9 0.0 5.5e-82 276.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO66278.1 - 3.8e-14 52.7 0.1 1.7e-13 50.6 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AEO66278.1 - 0.0042 16.3 0.2 0.0078 15.4 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO66278.1 - 0.027 14.2 0.2 0.058 13.1 0.1 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family DZR PF12773.2 AEO66280.1 - 0.0022 17.7 12.5 0.46 10.3 3.1 2.9 1 1 2 3 3 3 3 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 AEO66280.1 - 0.0027 17.3 12.8 0.42 10.2 0.2 3.9 3 1 1 4 4 4 2 Putative transposase DNA-binding domain DUF2709 PF10915.3 AEO66280.1 - 0.022 13.7 0.1 0.79 8.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2709) Terminase_GpA PF05876.7 AEO66280.1 - 1 7.6 4.9 1.3 7.3 3.4 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Fer4_10 PF13237.1 AEO66280.1 - 1.9 8.3 11.6 2.9 7.7 3.5 2.8 1 1 2 3 3 3 0 4Fe-4S dicluster domain DUF1272 PF06906.6 AEO66280.1 - 7.8 6.4 11.8 6.2 6.7 0.5 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1272) LysM PF01476.15 AEO66281.1 - 7.3e-14 51.3 0.0 1.8e-05 24.5 0.0 3.0 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.14 AEO66281.1 - 2.8e-05 23.9 22.0 2.8e-05 23.9 15.2 2.9 2 1 1 3 3 3 1 Chitin recognition protein p450 PF00067.17 AEO66282.1 - 2.8e-63 214.0 0.0 3.7e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rsm1 PF08600.5 AEO66282.1 - 0.075 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Rsm1-like Ribosomal_L1 PF00687.16 AEO66283.1 - 4.4e-59 199.4 0.1 7.5e-59 198.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Palm_thioest PF02089.10 AEO66285.1 - 6.1e-59 199.2 0.0 7.8e-59 198.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.6 AEO66285.1 - 0.033 13.2 0.0 0.077 12.0 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) adh_short PF00106.20 AEO66286.1 - 1.5e-27 96.5 1.1 2.1e-27 96.0 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO66286.1 - 1.2e-17 64.5 0.0 1.4e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO66286.1 - 1.3e-07 31.4 0.5 2.5e-07 30.5 0.4 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO66286.1 - 2e-05 24.6 0.1 6.4e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 AEO66286.1 - 0.0047 16.4 0.5 0.015 14.8 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NmrA PF05368.8 AEO66286.1 - 0.13 11.5 0.0 0.26 10.4 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family Form_Nir_trans PF01226.12 AEO66287.1 - 1.4e-54 184.6 18.4 2.5e-36 124.8 7.2 2.0 1 1 1 2 2 2 2 Formate/nitrite transporter B12D PF06522.6 AEO66287.1 - 0.043 13.5 0.0 0.043 13.5 0.0 2.1 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit UPF0016 PF01169.14 AEO66287.1 - 1.3 9.1 8.8 0.85 9.8 0.3 3.0 3 0 0 3 3 3 0 Uncharacterized protein family UPF0016 Collagen PF01391.13 AEO66288.1 - 0.056 12.9 8.5 0.12 11.9 5.9 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Vpu PF00558.14 AEO66288.1 - 0.17 11.4 0.2 0.3 10.6 0.1 1.2 1 0 0 1 1 1 0 Vpu protein zf-RING_2 PF13639.1 AEO66291.1 - 9.4e-10 38.1 7.2 2.2e-09 36.9 5.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AEO66291.1 - 7.3e-09 35.6 3.3 1.7e-08 34.4 2.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 AEO66291.1 - 6.3e-07 29.1 2.5 1.6e-06 27.8 1.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 AEO66291.1 - 2.9e-06 27.1 4.8 8.8e-06 25.6 3.3 1.9 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 AEO66291.1 - 7.8e-05 22.2 7.8 0.00015 21.3 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 AEO66291.1 - 0.00023 21.1 5.6 0.00049 20.0 3.9 1.6 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4_3 PF13920.1 AEO66291.1 - 0.00073 19.1 3.8 0.0012 18.4 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO66291.1 - 0.0026 17.7 8.4 0.0051 16.8 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 AEO66291.1 - 0.039 13.6 1.2 0.078 12.7 0.8 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.1 AEO66291.1 - 0.08 12.6 7.6 0.14 11.9 5.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.3 AEO66291.1 - 0.33 10.4 4.0 0.65 9.5 2.8 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 AEO66291.1 - 0.45 10.5 7.0 0.84 9.6 4.8 1.5 1 0 0 1 1 1 0 RING-like domain SKG6 PF08693.5 AEO66292.1 - 0.017 14.3 0.5 0.054 12.8 0.4 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain APH PF01636.18 AEO66293.1 - 2.1e-09 37.4 1.1 3.8e-09 36.6 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family FAR1 PF03101.10 AEO66294.1 - 1.4e-08 35.1 0.2 1.4e-08 35.1 0.1 3.4 3 1 0 3 3 3 1 FAR1 DNA-binding domain zf-C2H2_4 PF13894.1 AEO66295.1 - 0.0001 22.3 5.7 0.0072 16.5 0.6 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO66295.1 - 0.00011 22.3 5.0 0.0092 16.2 0.6 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 AEO66295.1 - 0.002 18.2 5.5 0.021 15.0 0.0 3.2 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-Di19 PF05605.7 AEO66295.1 - 0.0048 16.9 1.0 0.039 14.0 0.3 2.2 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-U11-48K PF05253.7 AEO66295.1 - 0.045 13.4 0.3 0.045 13.4 0.2 3.0 3 0 0 3 3 3 0 U11-48K-like CHHC zinc finger zf-ribbon_3 PF13248.1 AEO66295.1 - 0.22 10.7 2.6 8 5.8 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain CCAP PF11105.3 AEO66295.1 - 0.29 10.8 1.4 0.34 10.6 0.5 1.5 1 1 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a DUF2946 PF11162.3 AEO66295.1 - 2.2 8.4 7.4 5.5 7.2 5.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) UPF0547 PF10571.4 AEO66295.1 - 5.8 6.6 6.4 5.9 6.6 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 OTT_1508_deam PF14441.1 AEO66297.1 - 5.6e-19 68.3 0.0 2e-18 66.5 0.0 1.8 2 0 0 2 2 2 1 OTT_1508-like deaminase SNO PF01174.14 AEO66298.1 - 2.3e-51 174.0 0.0 5.7e-50 169.5 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 AEO66298.1 - 2.7e-10 40.0 0.2 1.9e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain DUF4066 PF13278.1 AEO66298.1 - 0.0016 17.7 0.1 0.0026 17.0 0.1 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 AEO66298.1 - 0.0025 17.2 0.1 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 AEO66298.1 - 0.0036 16.7 0.0 0.37 10.2 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Peptidase_S51 PF03575.12 AEO66298.1 - 0.0098 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 SOR_SNZ PF01680.12 AEO66299.1 - 2.5e-103 344.1 7.9 3.4e-103 343.6 5.5 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 AEO66299.1 - 2.3e-06 26.8 12.6 0.00048 19.2 0.9 2.9 1 1 2 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 AEO66299.1 - 0.00012 21.3 0.5 0.014 14.6 0.0 2.3 2 0 0 2 2 2 2 Histidine biosynthesis protein Dus PF01207.12 AEO66299.1 - 0.00016 20.6 0.2 0.19 10.5 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 AEO66299.1 - 0.01 14.8 2.0 0.091 11.7 0.0 2.8 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Trp_syntA PF00290.15 AEO66299.1 - 0.041 12.4 0.0 0.077 11.5 0.0 1.4 1 0 0 1 1 1 0 Tryptophan synthase alpha chain IGPS PF00218.16 AEO66299.1 - 0.08 11.9 0.4 0.38 9.7 0.0 2.3 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase NMO PF03060.10 AEO66299.1 - 0.35 9.9 13.9 0.02 14.0 2.7 2.5 2 1 0 2 2 2 0 Nitronate monooxygenase Sin_N PF04801.8 AEO66301.1 - 4.6e-19 68.5 0.0 1.4e-18 66.9 0.0 1.6 1 1 0 1 1 1 1 Sin-like protein conserved region PAT1 PF09770.4 AEO66302.1 - 9.4e-238 791.5 9.7 1.1e-237 791.3 6.7 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.11 AEO66303.1 - 5.1e-145 482.5 5.4 6.2e-145 482.2 3.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CDI PF02234.14 AEO66303.1 - 0.22 11.3 3.7 0.3 10.9 0.8 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor Ribosom_S12_S23 PF00164.20 AEO66304.1 - 5.8e-40 135.5 0.9 7.1e-40 135.2 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acyl-CoA_dh_1 PF00441.19 AEO66305.1 - 3.5e-42 144.0 5.0 5.1e-42 143.5 3.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 AEO66305.1 - 5.8e-28 97.7 0.3 3.6e-27 95.1 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 AEO66305.1 - 6.6e-17 62.0 1.3 9.7e-17 61.4 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 AEO66305.1 - 8.4e-17 60.4 0.0 1.5e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.3 AEO66305.1 - 0.0061 15.9 0.1 0.032 13.6 0.1 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HR1 PF02185.11 AEO66306.1 - 3.6e-26 90.6 26.2 5e-16 58.1 4.1 2.7 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.17 AEO66306.1 - 1e-20 73.1 25.6 3e-12 46.0 6.5 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.20 AEO66306.1 - 1.5e-14 53.8 0.1 2.8e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO66306.1 - 3e-08 33.0 0.1 3e-08 33.0 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase DUF605 PF04652.11 AEO66306.1 - 5.2 6.3 39.1 0.6 9.4 15.1 3.3 3 0 0 3 3 3 0 Vta1 like She9_MDM33 PF05546.6 AEO66307.1 - 7e-81 270.7 3.7 9.5e-81 270.3 2.6 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family ADIP PF11559.3 AEO66307.1 - 0.13 12.1 5.0 0.074 12.9 2.0 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding PsbH PF00737.15 AEO66307.1 - 0.14 11.7 0.4 0.24 11.0 0.3 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Nup54 PF13874.1 AEO66307.1 - 0.16 11.6 3.7 0.054 13.1 0.5 1.8 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 FAD-SLDH PF12318.3 AEO66307.1 - 0.36 10.5 5.0 0.55 9.8 2.4 2.1 1 1 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Spectrin PF00435.16 AEO66307.1 - 1.3 9.3 6.7 3.1 8.1 1.2 2.9 2 1 1 3 3 3 0 Spectrin repeat Tropomyosin_1 PF12718.2 AEO66307.1 - 1.9 8.3 11.7 0.046 13.5 2.9 2.1 2 1 0 2 2 2 0 Tropomyosin like DUF4140 PF13600.1 AEO66307.1 - 4.2 7.8 12.7 0.58 10.6 1.0 3.3 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) CobT PF06213.7 AEO66308.1 - 3.3 6.7 5.9 4.9 6.1 4.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Dicty_REP PF05086.7 AEO66308.1 - 7.8 4.1 5.2 10 3.7 3.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HAD PF12710.2 AEO66309.1 - 8e-16 58.7 0.0 1.1e-15 58.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AEO66309.1 - 3.9e-05 23.9 0.0 0.0001 22.5 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 AEO66309.1 - 0.00063 19.1 0.0 0.0009 18.6 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.7 AEO66309.1 - 0.0079 15.3 0.1 0.087 11.9 0.1 2.2 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.21 AEO66309.1 - 0.015 15.7 0.0 0.3 11.4 0.0 2.3 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase eIF-1a PF01176.14 AEO66310.1 - 1.3e-13 50.1 0.0 1.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.8 AEO66311.1 - 1.2e-142 475.5 21.5 3.4e-142 474.0 14.9 1.6 1 1 0 1 1 1 1 ALG3 protein DAO PF01266.19 AEO66312.1 - 2.1e-20 72.9 1.6 2.4e-20 72.7 1.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Ribonuclease PF00545.15 AEO66314.1 - 6.7e-06 26.0 0.1 2e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 ribonuclease Ribonuclease PF00545.15 AEO66315.1 - 1.6e-05 24.8 0.3 0.00057 19.9 0.1 2.5 2 0 0 2 2 2 1 ribonuclease Thioredoxin PF00085.15 AEO66316.1 - 7.6e-25 86.6 0.0 9.6e-25 86.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AEO66316.1 - 8.8e-07 29.1 0.0 1.7e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AEO66316.1 - 2.2e-06 27.7 0.0 0.00086 19.3 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 AEO66316.1 - 0.001 18.6 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 AEO66316.1 - 0.0021 18.0 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 AEO66316.1 - 0.0033 16.9 0.2 0.16 11.5 0.1 2.1 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 AEO66316.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA family HyaE PF07449.6 AEO66316.1 - 0.054 13.3 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DcpS_C PF11969.3 AEO66317.1 - 1.7e-13 50.8 3.0 9.8e-13 48.3 2.1 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 AEO66317.1 - 3.5e-12 46.6 0.0 1e-11 45.2 0.0 1.8 1 1 0 1 1 1 1 HIT domain DUF1814 PF08843.6 AEO66318.1 - 7.4e-07 29.1 0.0 1.4e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) Rrp15p PF07890.7 AEO66321.1 - 2.3 8.2 10.2 0.22 11.5 2.9 2.2 2 0 0 2 2 2 0 Rrp15p Methyltransf_3 PF01596.12 AEO66324.1 - 4.9e-30 104.1 0.0 6.1e-30 103.8 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 AEO66324.1 - 2.7e-14 53.8 0.0 5.2e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO66324.1 - 3.8e-09 37.0 0.0 6.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO66324.1 - 5.8e-06 25.7 0.0 8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 AEO66324.1 - 1.6e-05 24.9 0.0 2.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO66324.1 - 0.00017 21.1 0.0 0.00034 20.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain DUF633 PF04816.7 AEO66324.1 - 0.0016 17.8 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF633) UPF0020 PF01170.13 AEO66324.1 - 0.013 15.0 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PCMT PF01135.14 AEO66324.1 - 0.02 14.3 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 AEO66324.1 - 0.029 14.7 0.0 0.086 13.2 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain CmcI PF04989.7 AEO66324.1 - 0.033 13.4 0.0 0.044 13.0 0.0 1.1 1 0 0 1 1 1 0 Cephalosporin hydroxylase PLA2G12 PF06951.6 AEO66326.1 - 1.6e-11 44.1 8.0 1.6e-11 44.1 5.5 1.9 2 0 0 2 2 2 1 Group XII secretory phospholipase A2 precursor (PLA2G12) CBM_4_9 PF02018.12 AEO66326.1 - 0.029 14.3 0.0 0.093 12.7 0.0 1.9 1 1 0 1 1 1 0 Carbohydrate binding domain DUF2382 PF09557.5 AEO66326.1 - 0.049 13.5 0.1 0.095 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2382) Nuf2 PF03800.9 AEO66327.1 - 7.5e-44 149.2 0.0 2.2e-43 147.7 0.0 1.8 1 0 0 1 1 1 1 Nuf2 family MscS_porin PF12795.2 AEO66327.1 - 0.48 9.6 44.0 0.21 10.8 18.5 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 AEO66327.1 - 0.72 8.9 11.7 1.1 8.3 3.5 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 AEO66327.1 - 0.95 9.3 44.7 0.71 9.7 3.8 3.8 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Adaptin_N PF01602.15 AEO66329.1 - 1.7e-98 330.2 0.0 2e-98 330.0 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 AEO66329.1 - 3e-13 49.8 5.5 6.2e-06 26.4 0.0 4.9 3 1 0 3 3 3 3 HEAT repeats HEAT PF02985.17 AEO66329.1 - 2.5e-10 39.5 0.3 0.047 13.7 0.0 5.9 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 AEO66329.1 - 2.5e-06 27.8 8.3 0.0012 19.2 0.0 5.7 5 0 0 5 5 5 1 HEAT-like repeat Cnd1 PF12717.2 AEO66329.1 - 0.0053 16.6 0.0 0.069 12.9 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 AEO66329.1 - 0.0099 15.8 1.7 0.62 10.0 0.0 3.2 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Nop14 PF04147.7 AEO66329.1 - 0.01 13.8 22.0 0.015 13.2 15.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 AEO66329.1 - 0.068 12.4 18.5 0.1 11.8 12.8 1.2 1 0 0 1 1 1 0 SDA1 zf-CCHC PF00098.18 AEO66331.1 - 0.0081 16.0 2.2 0.019 14.8 1.5 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 AEO66331.1 - 0.42 10.4 2.4 0.93 9.2 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle Metallophos PF00149.23 AEO66332.1 - 3.6e-42 144.0 0.7 4.4e-42 143.7 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 AEO66333.1 - 6.2e-56 188.9 0.0 6.7e-56 188.8 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor E1_DerP2_DerF2 PF02221.10 AEO66333.1 - 0.019 15.2 0.0 0.049 13.8 0.0 1.8 1 1 0 1 1 1 0 ML domain Syndecan PF01034.15 AEO66333.1 - 0.86 9.2 3.1 2.4 7.8 0.4 2.5 2 0 0 2 2 2 0 Syndecan domain KilA-N PF04383.8 AEO66334.1 - 0.056 13.0 0.0 0.37 10.4 0.0 2.1 1 1 0 1 1 1 0 KilA-N domain NAD_binding_2 PF03446.10 AEO66335.1 - 2.2e-37 128.3 0.1 3.5e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 AEO66335.1 - 2.6e-32 111.4 0.0 5.5e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 AEO66335.1 - 4.3e-07 30.2 0.6 1.2e-06 28.7 0.0 2.0 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 AEO66335.1 - 4.5e-06 25.6 0.1 6.6e-06 25.0 0.1 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.17 AEO66335.1 - 0.0014 19.1 0.1 0.0029 18.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 AEO66335.1 - 0.0044 17.3 0.0 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 AEO66335.1 - 0.0097 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 AEO66335.1 - 0.016 14.9 0.0 0.054 13.1 0.0 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 AEO66335.1 - 0.04 13.6 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RTA1 PF04479.8 AEO66336.1 - 1e-35 123.3 1.1 1.4e-35 122.8 0.8 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3040 PF11239.3 AEO66336.1 - 0.7 9.9 5.7 0.82 9.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Peptidase_S49_N PF08496.5 AEO66337.1 - 0.26 11.0 3.5 0.38 10.5 2.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4139 PF13598.1 AEO66337.1 - 3.6 6.8 12.2 0.24 10.6 3.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4139) RhoGEF PF00621.15 AEO66338.1 - 4.1e-27 95.2 1.1 8.2e-27 94.2 0.0 1.9 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.3 AEO66338.1 - 0.038 13.4 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) IncA PF04156.9 AEO66338.1 - 3.1 7.3 18.5 90 2.5 0.1 3.2 2 1 0 2 2 2 0 IncA protein AAA_13 PF13166.1 AEO66338.1 - 4.9 5.4 9.6 11 4.3 6.7 1.5 1 0 0 1 1 1 0 AAA domain HORMA PF02301.13 AEO66339.1 - 2.5e-14 53.2 0.0 3e-13 49.7 0.0 2.1 2 1 0 2 2 2 1 HORMA domain IBN_N PF03810.14 AEO66340.1 - 1.2e-11 44.3 0.1 2.8e-10 39.9 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain YccJ PF13993.1 AEO66340.1 - 6e-05 23.0 0.3 0.00019 21.4 0.2 1.8 1 0 0 1 1 1 1 YccJ-like protein CAS_CSE1 PF03378.10 AEO66340.1 - 0.00072 17.9 0.0 0.0022 16.3 0.0 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Xpo1 PF08389.7 AEO66340.1 - 0.052 13.4 0.0 0.51 10.2 0.0 2.8 3 0 0 3 3 3 0 Exportin 1-like protein PI31_Prot_N PF11566.3 AEO66341.1 - 8.6e-36 122.8 0.0 1e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 AEO66341.1 - 3.5e-14 53.1 31.5 3.5e-14 53.1 21.8 3.7 3 2 0 3 3 3 1 PI31 proteasome regulator DUF2036 PF09724.4 AEO66343.1 - 3.8e-10 39.4 0.0 4.2e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) IBR PF01485.16 AEO66344.1 - 0.0012 18.6 2.3 0.0012 18.6 1.6 4.1 3 1 0 3 3 3 2 IBR domain Rad4 PF03835.10 AEO66345.1 - 3.8e-29 100.9 0.0 1.3e-28 99.2 0.0 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 AEO66345.1 - 5.2e-26 90.1 0.1 1.1e-25 89.1 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 AEO66345.1 - 3.1e-21 74.6 0.1 6.7e-21 73.5 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 AEO66345.1 - 4.1e-14 52.6 0.1 4.1e-14 52.6 0.0 3.9 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 AEO66345.1 - 0.00029 21.0 0.0 0.0014 18.8 0.0 2.3 2 1 0 2 2 2 1 Transglutaminase-like superfamily zf-AN1 PF01428.11 AEO66346.1 - 3.8e-26 90.6 19.6 6.9e-14 51.4 5.1 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 AEO66346.1 - 0.0008 19.2 13.3 0.033 14.0 1.4 2.4 2 0 0 2 2 2 2 IBR domain Transp_Tc5_C PF04236.10 AEO66346.1 - 0.0034 17.5 15.0 0.15 12.3 3.7 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain HypA PF01155.14 AEO66346.1 - 6.2 6.5 8.7 0.75 9.5 0.4 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family MTP18 PF10558.4 AEO66347.1 - 1.2e-68 229.7 0.0 1.5e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF935 PF06074.7 AEO66347.1 - 0.15 10.7 0.0 0.69 8.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF935) DUF2611 PF11022.3 AEO66348.1 - 1.8e-27 95.2 0.1 2.3e-27 94.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) Lzipper-MIP1 PF14389.1 AEO66349.1 - 0.057 13.5 0.6 0.21 11.7 0.1 1.9 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF2282 PF10048.4 AEO66350.1 - 0.14 12.0 0.1 0.14 12.0 0.1 2.9 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2282) Pkinase PF00069.20 AEO66351.1 - 8.7e-05 21.7 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 AEO66351.1 - 0.00074 19.3 0.1 0.00074 19.3 0.1 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 AEO66351.1 - 0.011 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase EAP30 PF04157.11 AEO66353.1 - 2e-57 193.9 0.0 2.5e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 AEO66353.1 - 3.6e-27 93.9 0.0 5.9e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 AEO66353.1 - 0.00024 20.5 0.0 0.00042 19.7 0.0 1.4 1 0 0 1 1 1 1 GRAM domain zf-Sec23_Sec24 PF04810.10 AEO66353.1 - 0.0021 17.5 5.0 0.011 15.3 0.3 2.4 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 AEO66353.1 - 0.0061 15.6 1.1 0.0061 15.6 0.8 2.6 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 AEO66353.1 - 0.047 13.5 0.3 0.047 13.5 0.2 2.2 2 1 0 2 2 2 0 Double zinc ribbon SAC3_GANP PF03399.11 AEO66354.1 - 1.6e-63 213.9 0.9 2.1e-63 213.5 0.6 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 AEO66354.1 - 0.0079 15.9 0.1 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SH3_1 PF00018.23 AEO66355.1 - 2.8e-27 93.8 0.0 9.1e-14 50.5 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 AEO66355.1 - 5.5e-17 61.0 0.2 3.9e-08 32.7 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 AEO66355.1 - 1.3e-14 53.9 0.0 2.4e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 AEO66355.1 - 1.9e-12 46.4 0.0 1.1e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 AEO66355.1 - 5.1e-12 45.3 0.1 9.2e-12 44.4 0.1 1.4 1 0 0 1 1 1 1 PB1 domain HTH_Tnp_Tc5 PF03221.11 AEO66356.1 - 7.9e-17 60.8 2.5 1.7e-15 56.5 0.1 3.4 3 1 1 4 4 4 1 Tc5 transposase DNA-binding domain HTH_29 PF13551.1 AEO66356.1 - 2.7 8.1 7.3 0.19 11.8 0.2 2.6 3 0 0 3 3 3 0 Winged helix-turn helix adh_short PF00106.20 AEO66359.1 - 1.4e-15 57.6 1.6 2.5e-15 56.7 1.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO66359.1 - 7.1e-08 32.5 0.0 1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO66359.1 - 4.4e-05 23.2 1.0 4.4e-05 23.2 0.7 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 AEO66359.1 - 8.5e-05 22.0 0.1 0.00011 21.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO66359.1 - 0.038 14.0 0.9 0.25 11.3 0.3 2.1 2 0 0 2 2 2 0 NADH(P)-binding Fungal_trans PF04082.13 AEO66360.1 - 6e-18 64.6 0.0 2.2e-17 62.8 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3716 PF12511.3 AEO66362.1 - 1.4e-15 56.6 1.0 2.6e-15 55.7 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF3048 PF11258.3 AEO66362.1 - 0.2 10.7 0.0 2.2 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3048) DUF629 PF04780.7 AEO66362.1 - 1 7.8 0.1 13 4.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) MAD PF05557.8 AEO66363.1 - 2.7e-53 181.2 48.6 3.2e-53 180.9 33.7 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Mmp37 PF09139.6 AEO66364.1 - 4e-134 446.7 0.0 5.2e-134 446.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Pmp3 PF01679.12 AEO66366.1 - 5.3e-19 67.6 2.3 5.8e-19 67.5 1.6 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RseC_MucC PF04246.7 AEO66366.1 - 0.12 11.9 0.1 0.15 11.6 0.1 1.0 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC BIR PF00653.16 AEO66367.1 - 9.4e-40 134.8 3.0 2.7e-19 69.3 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain AT_hook PF02178.14 AEO66367.1 - 0.0016 17.8 10.6 0.34 10.7 2.9 3.9 2 0 0 2 2 2 2 AT hook motif p450 PF00067.17 AEO66368.1 - 8.2e-36 123.4 0.0 3.4e-32 111.5 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Aa_trans PF01490.13 AEO66370.1 - 4.1e-56 190.2 36.8 4.7e-56 190.0 25.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_M3 PF01432.15 AEO66371.1 - 3.7e-157 524.0 0.0 4.8e-157 523.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 AEO66371.1 - 0.036 14.1 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 Effector protein EF-hand_7 PF13499.1 AEO66372.1 - 3.3e-13 49.5 0.1 2e-10 40.6 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.1 AEO66372.1 - 1.2e-11 44.3 0.0 1.4e-05 24.8 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.1 AEO66372.1 - 3.1e-10 39.0 0.5 0.01 15.6 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 AEO66372.1 - 2.7e-09 36.5 0.3 0.00031 20.2 0.0 3.5 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 AEO66372.1 - 1.3e-07 30.3 0.9 0.011 15.0 0.0 4.3 4 1 0 4 4 4 3 EF hand EF-hand_5 PF13202.1 AEO66372.1 - 0.078 12.3 1.9 2 7.8 0.7 3.2 3 0 0 3 3 3 0 EF hand CoA_binding_2 PF13380.1 AEO66373.1 - 4.4e-26 91.3 0.0 5.5e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain DUF1425 PF07233.7 AEO66373.1 - 0.004 16.6 0.0 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1425) GTP1_OBG PF01018.17 AEO66373.1 - 0.083 12.5 0.2 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 GTP1/OBG muHD PF10291.4 AEO66375.1 - 1.1e-72 244.3 0.0 1.7e-72 243.7 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 AEO66375.1 - 4.5e-11 42.7 0.5 2e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain NUFIP1 PF10453.4 AEO66375.1 - 0.041 13.3 0.3 0.32 10.5 0.1 2.4 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) PAS_10 PF13596.1 AEO66375.1 - 0.41 10.9 1.7 1.5 9.1 0.1 2.4 2 0 0 2 2 2 0 PAS domain Pkinase PF00069.20 AEO66376.1 - 4.8e-31 107.8 0.0 6.9e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO66376.1 - 1.3e-09 37.5 0.0 1.8e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO66376.1 - 0.08 12.6 1.3 5.2 6.7 0.3 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family GMP_synt_C PF00958.17 AEO66377.1 - 2.5e-38 129.6 0.1 6.8e-38 128.2 0.0 1.8 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 AEO66377.1 - 5.9e-28 97.6 0.0 1.1e-27 96.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 AEO66377.1 - 8.8e-10 37.8 0.1 4e-06 25.9 0.1 2.2 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.11 AEO66377.1 - 0.00015 20.4 0.1 0.00035 19.2 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 AEO66377.1 - 0.00079 18.9 0.0 0.0025 17.3 0.0 1.8 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.14 AEO66377.1 - 0.00098 18.2 0.1 0.0015 17.6 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase ATP_bind_3 PF01171.15 AEO66377.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.16 AEO66377.1 - 0.0022 17.5 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase Peptidase_C26 PF07722.8 AEO66377.1 - 0.0034 16.8 0.0 0.0073 15.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 PAPS_reduct PF01507.14 AEO66377.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family QueC PF06508.8 AEO66377.1 - 0.022 14.0 0.0 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Fungal_trans_2 PF11951.3 AEO66378.1 - 1.8e-27 95.9 0.0 5.2e-22 77.9 0.1 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO66378.1 - 0.017 15.0 6.7 0.038 13.9 4.6 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 AEO66380.1 - 0.017 14.9 8.1 7.6 6.5 0.1 5.3 6 0 0 6 6 6 0 WD domain, G-beta repeat PQ-loop PF04193.9 AEO66381.1 - 4.6e-23 80.5 15.5 1.3e-12 47.1 1.7 3.0 3 0 0 3 3 3 2 PQ loop repeat DUF3796 PF12676.2 AEO66381.1 - 0.086 13.0 2.8 0.08 13.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) DUF1345 PF07077.6 AEO66381.1 - 0.62 9.5 7.4 13 5.2 2.9 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1345) DUF3328 PF11807.3 AEO66381.1 - 2.6 7.6 7.1 12 5.4 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3328) PAN_1 PF00024.21 AEO66382.1 - 4.6e-12 45.5 3.8 2.2e-07 30.5 0.5 2.4 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.1 AEO66382.1 - 1.8e-09 37.1 5.7 8.9e-06 25.3 0.7 2.4 2 0 0 2 2 2 2 PAN domain MANEC PF07502.9 AEO66382.1 - 0.037 14.0 2.6 0.23 11.4 0.1 2.3 2 0 0 2 2 2 0 MANEC domain PAN_3 PF08277.7 AEO66382.1 - 0.048 13.2 3.4 0.23 11.1 0.6 2.3 2 0 0 2 2 2 0 PAN-like domain R3H-assoc PF13902.1 AEO66383.1 - 3.5e-19 69.0 1.8 7.1e-19 68.0 1.2 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 AEO66383.1 - 0.0039 16.8 0.2 0.013 15.1 0.0 1.9 2 0 0 2 2 2 1 R3H domain UCR_TM PF02921.9 AEO66385.1 - 2.5e-18 66.0 1.8 2.5e-18 66.0 1.3 1.8 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 AEO66385.1 - 1.1e-17 63.4 0.0 1.7e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain MMS1_N PF10433.4 AEO66386.1 - 6.1e-102 341.3 0.0 8.3e-102 340.9 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 AEO66386.1 - 4.4e-56 190.2 0.0 7.7e-55 186.2 0.0 2.9 2 2 0 2 2 2 1 CPSF A subunit region PQQ_3 PF13570.1 AEO66386.1 - 0.035 14.3 0.1 35 4.8 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain Tannase PF07519.6 AEO66387.1 - 2.7e-73 247.2 1.0 1.3e-71 241.7 0.7 2.0 1 1 0 1 1 1 1 Tannase and feruloyl esterase Asp PF00026.18 AEO66389.1 - 2.3e-28 99.3 0.1 1.6e-27 96.5 0.1 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 AEO66389.1 - 0.00052 20.4 0.1 1.3 9.5 0.0 3.2 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 AEO66389.1 - 0.0012 18.4 0.0 0.0083 15.6 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal DUF4402 PF14352.1 AEO66389.1 - 0.031 14.7 0.1 0.064 13.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) Glyco_hydro_35 PF01301.14 AEO66390.1 - 9.7e-97 324.1 0.0 1.4e-96 323.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 AEO66390.1 - 8e-62 207.8 1.6 1.4e-61 207.0 1.1 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 AEO66390.1 - 2.9e-55 185.2 4.1 1.4e-32 112.2 1.4 2.9 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 AEO66390.1 - 1e-21 76.0 0.1 2.3e-21 74.9 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 DJ-1_PfpI PF01965.19 AEO66391.1 - 1e-28 99.6 1.2 2.1e-28 98.6 0.8 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 AEO66391.1 - 2.1e-20 71.9 0.2 4.2e-20 70.9 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family MIP PF00230.15 AEO66393.1 - 6e-29 101.1 8.9 8.5e-29 100.6 6.2 1.2 1 0 0 1 1 1 1 Major intrinsic protein Cellulase PF00150.13 AEO66394.1 - 1.2e-22 80.4 2.7 1.5e-22 80.1 1.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 AEO66394.1 - 1.7e-05 23.8 0.1 5.2e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 AEO66394.1 - 0.00027 20.1 0.2 0.00066 18.8 0.2 1.6 1 0 0 1 1 1 1 Beta-galactosidase Cellulase-like PF12876.2 AEO66394.1 - 0.0014 19.0 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_10 PF00331.15 AEO66394.1 - 0.016 14.2 0.3 0.029 13.4 0.2 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 10 PKD_channel PF08016.7 AEO66395.1 - 2.3e-06 26.3 8.2 0.002 16.6 0.8 2.2 1 1 1 2 2 2 2 Polycystin cation channel Ion_trans PF00520.26 AEO66395.1 - 4.1e-06 26.1 12.6 4.1e-06 26.1 8.7 2.7 2 1 0 2 2 2 1 Ion transport protein Mto2_bdg PF12808.2 AEO66395.1 - 0.033 14.2 0.1 0.088 12.9 0.0 1.8 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF3814 PF12769.2 AEO66395.1 - 0.055 13.6 0.2 0.14 12.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3814) HET PF06985.6 AEO66396.1 - 7.2e-05 22.9 0.3 0.0015 18.6 0.0 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Trns_repr_metal PF02583.12 AEO66396.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor APH PF01636.18 AEO66399.1 - 5.5e-20 72.1 0.1 1.2e-19 71.0 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 AEO66399.1 - 0.0046 15.9 0.0 0.017 14.1 0.0 1.8 2 0 0 2 2 2 1 Fructosamine kinase Choline_kinase PF01633.15 AEO66399.1 - 0.084 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-C2H2_4 PF13894.1 AEO66400.1 - 0.0014 18.8 13.3 0.038 14.3 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO66400.1 - 0.19 12.0 5.6 0.2 12.0 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AEO66400.1 - 0.33 11.1 1.6 73 3.6 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO66400.1 - 4.3 7.6 6.2 1.9 8.8 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Acyl_transf_3 PF01757.17 AEO66401.1 - 2.4e-32 112.0 32.4 3.2e-32 111.7 22.4 1.2 1 0 0 1 1 1 1 Acyltransferase family Gly_transf_sug PF04488.10 AEO66402.1 - 8e-12 45.4 2.8 8.6e-12 45.3 0.1 2.3 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Acetyltransf_6 PF13480.1 AEO66402.1 - 0.071 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SprA-related PF12118.3 AEO66402.1 - 0.18 11.1 21.5 0.25 10.6 14.9 1.2 1 0 0 1 1 1 0 SprA-related family Pilt PF15453.1 AEO66402.1 - 2.1 7.9 19.1 2.9 7.4 13.3 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions GAGA_bind PF06217.7 AEO66402.1 - 3.1 7.6 17.4 5.4 6.8 12.1 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 AEO66402.1 - 4.6 6.9 18.0 3 7.5 11.3 1.5 2 0 0 2 2 2 0 DDHD domain CAF-1_p150 PF11600.3 AEO66402.1 - 8.1 5.7 59.6 12 5.1 41.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Oxidored_FMN PF00724.15 AEO66404.1 - 2.3e-92 309.6 0.0 2.6e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Mod_r PF07200.8 AEO66405.1 - 0.03 14.2 2.5 0.063 13.1 1.8 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein zf-CCHC_4 PF14392.1 AEO66405.1 - 0.047 13.3 6.1 0.054 13.1 0.8 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 AEO66405.1 - 0.059 13.3 6.3 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 Zinc knuckle DUF913 PF06025.7 AEO66405.1 - 0.21 10.2 0.7 0.37 9.4 0.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1682 PF07946.9 AEO66405.1 - 8.2 5.1 8.3 17 4.1 5.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1682) CAP59_mtransfer PF11735.3 AEO66406.1 - 7.4e-87 290.5 0.0 9.9e-87 290.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 HD_3 PF13023.1 AEO66407.1 - 1.3e-47 161.5 0.0 1.7e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 HD domain PLRV_ORF5 PF01690.12 AEO66409.1 - 6.4 5.7 8.8 11 5.0 6.1 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein AA_permease PF00324.16 AEO66410.1 - 1.9e-100 336.4 41.0 2.2e-100 336.2 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO66410.1 - 2.4e-25 88.9 42.9 3.2e-25 88.5 29.7 1.2 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_75 PF07335.6 AEO66412.1 - 3.4e-44 150.4 0.1 4.7e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Nucleoporin_C PF03177.9 AEO66414.1 - 2.2e-142 475.6 1.3 2.9e-142 475.1 0.9 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 AEO66414.1 - 1e-92 311.1 0.3 1.4e-92 310.6 0.2 1.2 1 0 0 1 1 1 1 Nup133 N terminal like adh_short PF00106.20 AEO66415.1 - 6.6e-24 84.7 0.0 9.4e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO66415.1 - 3.8e-13 49.7 0.0 5.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO66415.1 - 2e-08 34.1 0.0 4.4e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO66415.1 - 0.00071 19.6 0.2 0.002 18.1 0.0 1.9 2 1 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 AEO66415.1 - 0.057 12.3 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 AEO66415.1 - 0.1 12.6 0.2 0.28 11.2 0.0 1.8 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 AEO66415.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Erg28 PF03694.8 AEO66416.1 - 3.3e-43 146.2 0.1 4e-43 145.9 0.1 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.17 AEO66417.1 - 1.2e-69 234.0 0.6 8.9e-69 231.1 0.2 2.1 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 AEO66417.1 - 1.8e-57 193.5 0.0 3.1e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 AEO66417.1 - 0.00018 22.0 0.0 0.0012 19.2 0.0 2.2 2 0 0 2 2 2 1 HIT domain SWIRM PF04433.12 AEO66418.1 - 2.6e-12 46.6 0.0 9e-12 44.9 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 AEO66418.1 - 3.5e-10 39.2 5.8 6.2e-10 38.4 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 AEO66418.1 - 2.4e-07 30.6 0.1 1.1e-06 28.5 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain SHOCT PF09851.4 AEO66418.1 - 0.017 14.5 0.5 0.063 12.7 0.4 2.0 1 0 0 1 1 1 0 Short C-terminal domain zf-C3HC4_2 PF13923.1 AEO66418.1 - 0.11 12.5 2.2 0.28 11.2 1.5 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.20 AEO66419.1 - 0.012 15.5 0.3 0.012 15.5 0.2 1.9 2 0 0 2 2 2 0 short chain dehydrogenase Mg_trans_NIPA PF05653.9 AEO66420.1 - 2.6e-90 302.4 22.2 3.5e-90 301.9 15.4 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 AEO66420.1 - 1.9e-08 34.4 3.8 1.9e-08 34.4 2.6 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 AEO66420.1 - 7.7e-06 25.9 6.8 7.7e-06 25.9 4.7 2.9 2 1 0 2 2 2 1 EamA-like transporter family DUF914 PF06027.7 AEO66420.1 - 0.0026 16.6 1.7 0.0026 16.6 1.2 2.1 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) YbhQ PF11076.3 AEO66420.1 - 0.11 12.0 3.2 0.27 10.8 2.2 1.6 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ Ras PF00071.17 AEO66421.1 - 6.6e-18 64.6 0.0 1.6e-05 24.3 0.0 4.1 4 0 0 4 4 4 4 Ras family Miro PF08477.8 AEO66421.1 - 1.9e-05 25.1 0.0 0.0038 17.7 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein U-box PF04564.10 AEO66422.1 - 1.5e-18 66.5 0.0 2.6e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 AEO66422.1 - 1.4e-10 40.6 3.1 3.2e-10 39.4 2.2 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 AEO66422.1 - 1.9e-07 30.4 2.4 0.0033 17.2 1.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 AEO66422.1 - 9.3e-07 28.2 1.6 0.0034 16.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO66422.1 - 2e-05 25.1 1.1 5.6e-05 23.6 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 AEO66422.1 - 0.00021 21.1 11.8 0.0035 17.2 2.0 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO66422.1 - 0.0033 17.1 0.4 2.3 8.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 AEO66422.1 - 0.013 15.6 1.2 0.025 14.6 0.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 AEO66422.1 - 0.037 14.6 0.7 4.5 8.1 0.3 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat LUC7 PF03194.10 AEO66422.1 - 0.083 12.4 1.8 0.13 11.7 1.2 1.3 1 1 0 1 1 1 0 LUC7 N_terminus TPR_7 PF13176.1 AEO66422.1 - 0.11 12.3 0.8 25 5.0 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat SH3_9 PF14604.1 AEO66425.1 - 1.6e-10 40.4 0.0 2.9e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AEO66425.1 - 5.6e-06 25.6 0.0 9.3e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AEO66425.1 - 0.0001 21.7 0.0 0.00022 20.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain IncA PF04156.9 AEO66425.1 - 0.027 14.0 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 IncA protein Plasmodium_Vir PF05795.6 AEO66425.1 - 0.061 12.5 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TMEM154 PF15102.1 AEO66425.1 - 0.064 12.9 0.2 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.1 AEO66425.1 - 0.065 11.7 0.0 0.092 11.2 0.0 1.1 1 0 0 1 1 1 0 Amnionless Mid2 PF04478.7 AEO66425.1 - 0.08 12.3 2.1 0.083 12.2 0.3 1.9 2 1 0 2 2 2 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.1 AEO66425.1 - 0.19 12.1 0.0 0.38 11.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gar1 PF04410.9 AEO66426.1 - 1.7e-47 160.7 0.2 1.7e-47 160.7 0.2 2.8 4 0 0 4 4 4 1 Gar1/Naf1 RNA binding region Glyco_transf_22 PF03901.12 AEO66427.1 - 9.3e-88 295.0 19.4 1.1e-87 294.7 13.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family F-box-like PF12937.2 AEO66428.1 - 0.00031 20.4 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 F-box-like Exo5 PF09810.4 AEO66429.1 - 3.3e-112 374.8 0.0 4.5e-112 374.4 0.0 1.2 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 AEO66429.1 - 2.4e-06 27.1 1.0 2.2e-05 23.9 0.0 2.6 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily tRNA-synt_2b PF00587.20 AEO66430.1 - 4e-21 75.3 0.0 7.6e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 AEO66430.1 - 1.3e-20 73.0 0.2 2.9e-20 71.9 0.1 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 AEO66430.1 - 4.4e-16 58.5 0.0 9.7e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Cpn60_TCP1 PF00118.19 AEO66431.1 - 5.1e-145 483.8 12.5 5.8e-145 483.6 8.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_int_SAM_1 PF02899.12 AEO66431.1 - 0.13 12.4 0.1 0.65 10.1 0.0 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Acetyltransf_7 PF13508.1 AEO66432.1 - 3.1e-07 30.4 0.0 8.3e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO66432.1 - 0.00013 21.9 0.4 0.00083 19.3 0.1 2.5 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 AEO66432.1 - 0.00021 21.1 0.2 0.0015 18.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO66432.1 - 0.047 13.8 1.8 0.16 12.1 0.1 2.6 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AEO66432.1 - 0.084 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase tRNA-synt_1 PF00133.17 AEO66433.1 - 2.8e-153 511.1 0.2 1.8e-86 290.4 0.0 2.0 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 AEO66433.1 - 1.2e-08 34.0 0.7 6.4e-05 21.7 0.0 3.0 3 1 0 3 3 3 2 tRNA synthetases class I (M) DUF3545 PF12065.3 AEO66433.1 - 0.038 13.7 0.1 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) AFG1_ATPase PF03969.11 AEO66434.1 - 1e-96 323.9 0.0 2.8e-91 306.0 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 AEO66434.1 - 2.7e-06 27.5 0.4 0.0053 16.7 0.0 3.2 2 1 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 AEO66434.1 - 0.00037 20.4 0.0 0.00086 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO66434.1 - 0.00071 19.3 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 AEO66434.1 - 0.00076 19.6 0.0 0.029 14.5 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO66434.1 - 0.0047 17.0 0.0 0.021 14.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 AEO66434.1 - 0.0094 15.6 0.1 0.35 10.4 0.0 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein Sigma54_activ_2 PF14532.1 AEO66434.1 - 0.019 15.0 0.0 0.075 13.0 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 AEO66434.1 - 0.056 13.7 0.0 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 AEO66434.1 - 0.096 12.8 0.0 0.28 11.3 0.0 1.9 1 1 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 AEO66434.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase Peptidase_M28 PF04389.12 AEO66435.1 - 3.6e-26 91.9 0.0 5.8e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 AEO66435.1 - 9.4e-07 28.5 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 AEO66435.1 - 0.1 11.3 0.1 1.7 7.3 0.0 2.1 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase PLDc_2 PF13091.1 AEO66436.1 - 2.7e-16 59.4 0.0 8e-08 32.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 AEO66436.1 - 0.00053 19.7 0.1 0.47 10.3 0.0 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 AEO66436.1 - 0.0024 16.8 0.1 0.97 8.3 0.0 2.7 3 0 0 3 3 3 2 Archaeal transcriptional regulator TrmB Cu_bind_like PF02298.12 AEO66437.1 - 0.028 14.1 0.4 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Plastocyanin-like domain DUF605 PF04652.11 AEO66438.1 - 0.06 12.7 26.0 0.089 12.1 18.0 1.3 1 0 0 1 1 1 0 Vta1 like NUC153 PF08159.7 AEO66439.1 - 2.6e-14 52.4 7.6 2.9e-14 52.3 0.3 3.6 3 0 0 3 3 3 1 NUC153 domain OPT PF03169.10 AEO66440.1 - 2.9e-81 273.7 35.0 1.6e-41 142.5 1.4 2.1 1 1 1 2 2 2 2 OPT oligopeptide transporter protein NB-ARC PF00931.17 AEO66441.1 - 5.9e-07 28.6 0.0 2.8e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 AEO66441.1 - 7.9e-07 28.9 0.4 0.054 13.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_16 PF13191.1 AEO66441.1 - 0.0012 18.8 0.0 0.0045 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AEO66441.1 - 0.0029 17.7 0.0 0.011 15.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain Ubie_methyltran PF01209.13 AEO66442.1 - 1.3e-11 44.1 0.0 1.8e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AEO66442.1 - 4.7e-11 43.0 0.0 1.5e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO66442.1 - 1.6e-09 37.5 0.0 3.3e-09 36.4 0.0 1.5 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO66442.1 - 4.1e-09 36.4 0.0 7.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO66442.1 - 1.9e-07 31.4 0.0 4.8e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO66442.1 - 6.7e-07 29.6 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO66442.1 - 2.9e-05 23.4 0.0 7.4e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.1 AEO66442.1 - 0.00051 19.8 0.0 0.00081 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO66442.1 - 0.0014 19.1 0.0 0.0028 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cyt-b5 PF00173.23 AEO66444.1 - 3.7e-15 55.4 0.0 8.3e-12 44.7 0.0 3.3 2 1 1 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Neisseria_TspB PF05616.8 AEO66446.1 - 0.092 11.1 1.4 0.1 10.9 1.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF3275 PF11679.3 AEO66448.1 - 0.14 11.7 0.5 0.23 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Cyclin_N PF00134.18 AEO66449.1 - 1.5e-09 37.4 0.0 2.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain NmrA PF05368.8 AEO66450.1 - 1.7e-52 178.0 0.0 2e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO66450.1 - 1.6e-15 57.5 0.2 2.2e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 AEO66450.1 - 1.1e-05 25.3 0.0 2e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 AEO66450.1 - 0.00022 20.0 0.0 0.00029 19.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 AEO66450.1 - 0.029 13.3 0.1 0.039 12.9 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase TPR_19 PF14559.1 AEO66454.1 - 0.00032 20.9 0.3 2.6 8.4 0.2 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat Glyco_hydro_18 PF00704.23 AEO66455.1 - 6.8e-19 68.5 0.6 5.3e-18 65.5 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 CBM_1 PF00734.13 AEO66455.1 - 2.1e-09 36.8 16.1 8.8e-09 34.8 11.2 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Phage_min_cap2 PF06152.6 AEO66457.1 - 0.063 12.2 5.1 0.08 11.9 3.5 1.0 1 0 0 1 1 1 0 Phage minor capsid protein 2 RskA PF10099.4 AEO66457.1 - 0.065 12.9 2.3 0.073 12.8 1.6 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Brix PF04427.13 AEO66458.1 - 6.8e-58 195.4 0.0 9.2e-58 195.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain DEAD PF00270.24 AEO66459.1 - 2.6e-48 163.6 0.0 5.9e-48 162.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO66459.1 - 1.4e-26 92.1 0.0 2.4e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO66459.1 - 9.8e-06 25.5 0.0 4.2e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 AEO66459.1 - 0.018 14.7 1.1 0.042 13.5 0.1 2.1 2 1 0 2 2 2 0 Part of AAA domain Flavi_DEAD PF07652.9 AEO66459.1 - 0.13 12.0 0.0 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain CwfJ_C_1 PF04677.10 AEO66460.1 - 2.3e-24 85.3 0.0 4.1e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 AEO66460.1 - 2.5e-24 85.6 0.1 9e-24 83.8 0.1 2.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 MIP-T3 PF10243.4 AEO66460.1 - 2.6 6.4 31.2 3.7 5.9 21.6 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Metaviral_G PF09595.5 AEO66461.1 - 1.1 8.8 3.8 2.2 7.8 2.7 1.4 1 1 0 1 1 1 0 Metaviral_G glycoprotein ATP_bind_1 PF03029.12 AEO66462.1 - 3.2e-74 249.4 0.0 4.7e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 AEO66462.1 - 5.7e-08 32.4 0.4 8.9e-07 28.5 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 AEO66462.1 - 3.9e-06 25.8 0.1 0.04 12.6 0.0 2.2 2 0 0 2 2 2 2 ArgK protein AAA_33 PF13671.1 AEO66462.1 - 0.00011 22.1 1.1 0.00029 20.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AEO66462.1 - 0.00011 22.3 0.0 0.00032 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 AEO66462.1 - 0.00038 20.3 0.0 0.0011 18.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 AEO66462.1 - 0.00059 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_10 PF12846.2 AEO66462.1 - 0.00086 18.8 0.8 0.0045 16.4 0.6 2.1 1 1 0 1 1 1 1 AAA-like domain Miro PF08477.8 AEO66462.1 - 0.00097 19.6 0.0 0.53 10.7 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 AEO66462.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.14 AEO66462.1 - 0.0017 17.8 0.0 0.016 14.6 0.0 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 AEO66462.1 - 0.0026 17.1 0.2 0.0051 16.2 0.0 1.6 2 0 0 2 2 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.13 AEO66462.1 - 0.0038 16.7 1.2 0.011 15.2 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 AEO66462.1 - 0.0038 16.9 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 AEO66462.1 - 0.0054 15.9 0.0 1.4 8.0 0.0 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_19 PF13245.1 AEO66462.1 - 0.0057 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 AEO66462.1 - 0.0066 16.1 0.1 0.034 13.8 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase DUF87 PF01935.12 AEO66462.1 - 0.0072 16.1 0.3 0.16 11.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 FeoB_N PF02421.13 AEO66462.1 - 0.0082 15.4 0.0 0.16 11.2 0.0 2.5 3 0 0 3 3 2 1 Ferrous iron transport protein B SRP54 PF00448.17 AEO66462.1 - 0.0086 15.5 0.0 0.049 13.0 0.0 2.2 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain NB-ARC PF00931.17 AEO66462.1 - 0.01 14.6 0.0 0.021 13.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 AEO66462.1 - 0.015 15.1 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF89 PF01937.14 AEO66462.1 - 0.017 13.9 0.3 0.025 13.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF89 AAA_17 PF13207.1 AEO66462.1 - 0.024 15.4 3.7 0.051 14.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain Arf PF00025.16 AEO66462.1 - 0.029 13.6 0.0 7.3 5.8 0.0 3.0 2 1 0 2 2 2 0 ADP-ribosylation factor family UPF0079 PF02367.12 AEO66462.1 - 0.032 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 AEO66462.1 - 0.04 13.4 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 AEO66462.1 - 0.043 13.3 0.1 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.9 AEO66462.1 - 0.046 13.4 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) LpxK PF02606.9 AEO66462.1 - 0.065 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase Pox_A32 PF04665.7 AEO66462.1 - 0.11 11.7 0.0 0.39 9.9 0.0 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein RNA_helicase PF00910.17 AEO66462.1 - 0.12 12.5 0.1 0.47 10.6 0.0 2.0 2 0 0 2 2 1 0 RNA helicase G-alpha PF00503.15 AEO66462.1 - 0.13 10.9 1.1 1.3 7.6 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit PduV-EutP PF10662.4 AEO66462.1 - 0.15 11.5 0.2 1.8 8.0 0.0 2.6 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 AEO66462.1 - 0.18 11.1 0.9 2.1 7.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain Thymidylate_kin PF02223.12 AEO66462.1 - 0.23 10.8 0.0 0.23 10.8 0.0 2.4 3 0 0 3 3 2 0 Thymidylate kinase AAA_23 PF13476.1 AEO66462.1 - 0.24 11.7 1.8 16 5.7 0.8 2.3 2 0 0 2 2 2 0 AAA domain UPF0149 PF03695.8 AEO66462.1 - 0.31 10.9 9.0 0.77 9.6 6.3 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0149) AAA_18 PF13238.1 AEO66462.1 - 2.2 8.5 0.0 2.2 8.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain eIF-3c_N PF05470.7 AEO66462.1 - 3.5 5.5 8.3 5.2 5.0 5.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DNA_RNApol_7kD PF03604.8 AEO66463.1 - 3.2e-15 55.2 2.8 4.2e-15 54.9 2.0 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 AEO66463.1 - 0.012 15.4 0.3 0.017 14.8 0.2 1.2 1 0 0 1 1 1 0 Double zinc ribbon GFA PF04828.9 AEO66463.1 - 0.014 15.3 0.1 1.4 8.9 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn-ribbon_8 PF09723.5 AEO66463.1 - 0.049 13.5 0.6 0.076 12.9 0.4 1.3 1 0 0 1 1 1 0 Zinc ribbon domain HypA PF01155.14 AEO66463.1 - 0.12 12.0 0.3 0.16 11.7 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family HIT PF01230.18 AEO66464.1 - 1.6e-16 60.6 0.0 2.7e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 AEO66464.1 - 1.8e-06 28.1 0.0 2.5e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 AEO66464.1 - 0.0062 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Strep_his_triad PF04270.8 AEO66464.1 - 0.036 13.7 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Streptococcal histidine triad protein Aldo_ket_red PF00248.16 AEO66465.1 - 1.1e-50 172.0 0.0 1.3e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ChAPs PF09295.5 AEO66466.1 - 2.5e-161 536.9 0.0 3.1e-161 536.5 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 AEO66466.1 - 5.5e-07 29.6 2.7 0.44 11.3 0.3 5.2 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 AEO66466.1 - 5.2e-05 23.0 0.3 0.043 13.6 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 AEO66466.1 - 0.00011 21.8 0.4 0.077 12.9 0.5 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 AEO66466.1 - 0.00042 19.8 3.9 0.58 9.8 0.0 3.6 4 0 0 4 4 4 2 TPR repeat TPR_7 PF13176.1 AEO66466.1 - 0.00061 19.4 1.8 1.3 8.9 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 AEO66466.1 - 0.0007 19.8 0.3 2.2 8.6 0.0 3.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO66466.1 - 0.001 18.6 0.1 1.6 8.7 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO66466.1 - 0.0055 17.3 0.8 5.1 7.9 0.4 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 AEO66466.1 - 0.016 14.8 0.1 8.2 6.2 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 AEO66466.1 - 0.034 14.0 0.3 6.5 6.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO66466.1 - 0.035 14.5 0.3 32 5.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 AEO66466.1 - 0.059 13.5 3.5 3.7 7.7 0.0 3.5 4 0 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1967 PF09269.6 AEO66467.1 - 0.0017 17.9 0.2 0.022 14.4 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1967) TPR_17 PF13431.1 AEO66467.1 - 0.022 14.9 0.4 13 6.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1786 PF08735.5 AEO66467.1 - 0.027 13.6 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) TPR_11 PF13414.1 AEO66467.1 - 0.23 11.1 10.6 39 3.9 0.2 5.5 5 0 0 5 5 5 0 TPR repeat UQ_con PF00179.21 AEO66468.1 - 2.9e-40 136.9 0.0 3.3e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO66468.1 - 0.00014 21.6 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AEO66468.1 - 0.06 13.2 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain RabGAP-TBC PF00566.13 AEO66469.1 - 3.4e-36 124.7 0.0 1.4e-35 122.7 0.0 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Utp14 PF04615.8 AEO66470.1 - 5.6 5.0 34.0 6 4.9 23.6 1.0 1 0 0 1 1 1 0 Utp14 protein NmrA PF05368.8 AEO66471.1 - 8.7e-18 64.4 0.0 1.5e-17 63.6 0.0 1.4 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 AEO66471.1 - 7.6e-14 52.1 0.9 1.3e-13 51.3 0.6 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 AEO66471.1 - 1.1e-08 34.4 0.1 1.4e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 AEO66471.1 - 9.2e-05 21.2 0.1 0.00013 20.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AEO66471.1 - 0.00012 21.5 0.1 0.00018 21.0 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 AEO66471.1 - 0.00014 22.1 0.2 0.00044 20.5 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 AEO66471.1 - 0.002 17.1 0.2 0.0032 16.4 0.1 1.4 1 0 0 1 1 1 1 Male sterility protein F420_oxidored PF03807.12 AEO66471.1 - 0.0097 16.3 0.3 0.022 15.1 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 AEO66471.1 - 0.012 15.5 0.1 0.026 14.4 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 AEO66471.1 - 0.028 14.0 0.4 0.067 12.8 0.3 1.7 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 AEO66471.1 - 0.061 13.2 1.9 0.091 12.6 0.5 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Ldh_1_N PF00056.18 AEO66471.1 - 0.34 10.7 2.3 1.3 8.8 1.6 1.9 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain HLH PF00010.21 AEO66472.1 - 1.1e-10 41.0 0.0 2.7e-09 36.5 0.0 2.3 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Orbi_VP6 PF01516.11 AEO66472.1 - 0.16 10.9 4.8 0.25 10.3 3.3 1.3 1 0 0 1 1 1 0 Orbivirus helicase VP6 Claudin_3 PF06653.6 AEO66473.1 - 0.0094 15.6 1.1 0.014 15.1 0.7 1.2 1 0 0 1 1 1 1 Tight junction protein, Claudin-like MARVEL PF01284.18 AEO66473.1 - 3.6 7.3 6.7 9.7 6.0 4.6 1.7 1 1 0 1 1 1 0 Membrane-associating domain Peptidase_S24 PF00717.18 AEO66474.1 - 2.3e-07 30.3 0.0 3.5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like BTB PF00651.26 AEO66476.1 - 5.4e-08 32.8 0.0 1.3e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 AEO66476.1 - 0.0027 17.7 0.0 0.18 11.8 0.0 2.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF1349 PF07081.6 AEO66477.1 - 3.6e-13 49.2 0.0 8.3e-12 44.8 0.0 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) TFIIB PF00382.14 AEO66478.1 - 3.4e-29 100.4 4.0 5.6e-15 54.9 0.4 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 AEO66478.1 - 2e-20 72.7 0.2 2e-20 72.7 0.1 4.4 5 0 0 5 5 5 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 AEO66478.1 - 0.00067 19.2 0.3 0.021 14.3 0.0 2.3 1 1 1 2 2 2 1 Cyclin, N-terminal domain APH PF01636.18 AEO66481.1 - 2.7e-08 33.8 1.2 2.7e-08 33.8 0.9 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO66481.1 - 5.6e-05 22.8 0.0 8.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 AEO66481.1 - 0.11 11.6 0.0 12 4.9 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain EcKinase PF02958.15 AEO66481.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF2076 PF09849.4 AEO66482.1 - 0.00013 22.1 1.5 0.00019 21.5 1.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) SKG6 PF08693.5 AEO66482.1 - 0.0068 15.6 0.3 0.012 14.8 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DAP10 PF07213.6 AEO66482.1 - 0.009 15.7 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 DAP10 membrane protein DUF2615 PF11027.3 AEO66482.1 - 0.024 14.5 0.1 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) DUF1517 PF07466.6 AEO66482.1 - 0.1 11.5 0.9 0.19 10.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF3329 PF11808.3 AEO66482.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) Lipase_GDSL_2 PF13472.1 AEO66483.1 - 3.2e-15 56.7 0.3 4.6e-15 56.2 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO66483.1 - 4e-13 49.7 0.1 5.5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 AEO66483.1 - 2e-06 27.6 0.0 3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PrgH PF09480.5 AEO66483.1 - 0.09 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) Methyltransf_25 PF13649.1 AEO66484.1 - 2.1e-08 34.4 0.1 3.4e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.11 AEO66485.1 - 7.1e-19 67.7 46.5 8.9e-19 67.3 25.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO66485.1 - 1.9e-07 30.0 5.7 1.9e-07 30.0 3.9 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter DUF2975 PF11188.3 AEO66486.1 - 0.0079 15.9 1.4 0.022 14.4 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2975) Prokineticin PF06607.6 AEO66486.1 - 0.054 13.5 0.2 0.39 10.8 0.1 2.3 2 1 0 2 2 2 0 Prokineticin E1-E2_ATPase PF00122.15 AEO66487.1 - 3.8e-20 71.9 0.0 6.7e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AEO66487.1 - 5.8e-16 59.5 0.1 2e-11 44.7 0.0 3.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 AEO66487.1 - 2.8e-11 43.9 0.0 4.2e-10 40.0 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO66487.1 - 2.5e-10 40.1 0.0 8.5e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AEO66487.1 - 0.0032 17.1 0.0 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase UDPG_MGDP_dh_N PF03721.9 AEO66488.1 - 3.9e-40 137.2 0.0 1.5e-21 76.6 0.1 3.2 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 AEO66488.1 - 1.5e-29 102.0 0.0 3.2e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 AEO66488.1 - 5e-24 84.4 0.0 2.4e-18 66.2 0.0 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Saccharop_dh PF03435.13 AEO66488.1 - 0.00028 20.0 0.0 0.00083 18.4 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 AEO66488.1 - 0.00042 20.0 0.2 0.26 11.0 0.1 2.8 3 0 0 3 3 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 AEO66488.1 - 0.01 15.5 0.0 0.056 13.0 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain BcrAD_BadFG PF01869.15 AEO66488.1 - 0.02 14.2 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family F420_oxidored PF03807.12 AEO66488.1 - 0.047 14.1 0.3 4.9 7.6 0.1 3.4 3 1 1 4 4 4 0 NADP oxidoreductase coenzyme F420-dependent Glycos_transf_1 PF00534.15 AEO66489.1 - 3.2e-35 121.0 0.0 5.2e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AEO66489.1 - 4.8e-15 55.9 0.1 1.2e-14 54.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 AEO66489.1 - 2.2e-14 53.9 0.6 2.2e-14 53.9 0.4 2.4 2 1 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 AEO66489.1 - 1e-12 48.1 0.0 2e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 AEO66489.1 - 2.1e-06 27.6 0.0 8e-06 25.6 0.0 2.1 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Flavoprotein PF02441.14 AEO66489.1 - 0.0015 18.1 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein muHD PF10291.4 AEO66489.1 - 0.042 13.0 0.2 0.068 12.3 0.1 1.2 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain DUF718 PF05336.8 AEO66490.1 - 7.3e-36 122.1 0.1 8.8e-36 121.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF718) FPN1 PF06963.7 AEO66491.1 - 3.8e-124 414.3 10.4 4.4e-124 414.1 7.2 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Sulfatase PF00884.18 AEO66492.1 - 7.2e-45 153.4 0.0 2.4e-42 145.2 0.0 2.7 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 AEO66492.1 - 8.2e-08 31.9 0.0 1.9e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 AEO66492.1 - 0.0059 15.5 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Sulfatase_C PF14707.1 AEO66492.1 - 0.0083 16.4 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 AEO66492.1 - 0.049 12.0 0.0 0.061 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Glyco_hydro_28 PF00295.12 AEO66493.1 - 1.6e-31 109.4 0.5 2.1e-31 109.1 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 AEO66493.1 - 2.4e-07 31.1 8.1 0.00015 22.0 5.6 2.4 1 1 0 1 1 1 1 Pectate lyase superfamily protein MFS_1 PF07690.11 AEO66494.1 - 1.2e-15 57.1 15.6 1.7e-15 56.6 10.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2417 PF10329.4 AEO66494.1 - 0.2 11.0 2.8 3.3 7.0 0.4 2.7 3 0 0 3 3 3 0 Region of unknown function (DUF2417) Dynamin_N PF00350.18 AEO66496.1 - 4.9e-15 55.7 0.0 1.1e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 AEO66496.1 - 1.9e-11 43.2 0.0 3.9e-08 32.4 0.0 2.1 1 1 1 2 2 2 2 Dynamin central region T_hemolysin PF12261.3 AEO66496.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Thermostable hemolysin adh_short_C2 PF13561.1 AEO66497.1 - 3.6e-36 125.1 2.4 4e-36 124.9 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AEO66497.1 - 4.8e-25 88.3 7.3 8.1e-25 87.6 5.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO66497.1 - 2.4e-08 33.8 2.1 3.5e-08 33.3 1.5 1.2 1 0 0 1 1 1 1 KR domain Virul_Fac PF10139.4 AEO66497.1 - 0.077 10.9 0.0 0.11 10.4 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor AdoHcyase_NAD PF00670.16 AEO66497.1 - 0.078 12.8 3.3 0.14 11.9 2.3 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain VWA_2 PF13519.1 AEO66497.1 - 0.27 11.3 5.8 1.7 8.7 4.0 2.1 1 1 0 1 1 1 0 von Willebrand factor type A domain CoA_binding_2 PF13380.1 AEO66497.1 - 0.3 11.2 2.5 2.2 8.5 0.3 2.6 2 2 0 2 2 2 0 CoA binding domain Vps35 PF03635.12 AEO66499.1 - 0 1027.8 0.0 0 1027.6 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 TFR_dimer PF04253.10 AEO66500.1 - 9.1e-24 83.4 0.0 1.6e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 AEO66500.1 - 4e-11 42.9 0.0 7.1e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 AEO66500.1 - 2.9e-05 23.6 0.0 6.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 PA domain Repressor_Mnt PF11423.3 AEO66500.1 - 7.4 5.9 7.1 3.8 6.8 2.0 2.5 2 0 0 2 2 2 0 Regulatory protein Mnt Sigma70_r4_2 PF08281.7 AEO66501.1 - 2.8e-06 26.6 0.2 3.9e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.1 AEO66501.1 - 0.0037 16.8 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.1 AEO66501.1 - 0.045 13.1 0.1 0.065 12.6 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_29 PF13551.1 AEO66501.1 - 0.09 12.9 0.1 0.14 12.3 0.0 1.4 1 1 0 1 1 1 0 Winged helix-turn helix TENA_THI-4 PF03070.11 AEO66502.1 - 1.7e-08 34.4 0.0 4.5e-07 29.8 0.0 2.6 2 0 0 2 2 2 1 TENA/THI-4/PQQC family AAA PF00004.24 AEO66502.1 - 0.058 13.5 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SM_b PF10741.4 AEO66502.1 - 0.059 13.0 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b CorA PF01544.13 AEO66502.1 - 0.059 12.4 0.0 0.2 10.6 0.0 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein FAM180 PF15173.1 AEO66503.1 - 0.0061 16.3 0.4 0.49 10.1 0.0 2.1 1 1 1 2 2 2 2 FAM180 family GFA PF04828.9 AEO66506.1 - 5.1e-15 55.1 0.1 7.4e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Guanylate_kin PF00625.16 AEO66507.1 - 3e-62 209.3 0.0 3.4e-62 209.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 AEO66507.1 - 2.7e-08 33.7 0.0 8.1e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO66507.1 - 2.2e-05 24.7 0.0 7.5e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AEO66507.1 - 0.0004 20.5 0.0 0.0018 18.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AEO66507.1 - 0.00096 19.9 0.1 0.002 18.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AEO66507.1 - 0.0022 17.1 0.0 0.005 16.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Tail_tube PF10618.4 AEO66507.1 - 0.0091 15.7 0.1 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Phage tail tube protein AAA_16 PF13191.1 AEO66507.1 - 0.011 15.7 0.0 0.015 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 AEO66507.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 AEO66507.1 - 0.029 13.9 0.0 0.068 12.7 0.0 1.5 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 AEO66507.1 - 0.042 14.1 0.0 0.047 13.9 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 AEO66507.1 - 0.067 13.1 0.2 0.51 10.2 0.0 2.2 1 1 1 2 2 2 0 AAA domain TBP PF00352.16 AEO66508.1 - 5.6e-55 182.6 0.0 8.7e-28 95.5 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 AEO66508.1 - 0.0012 18.9 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF1308 PF07000.6 AEO66508.1 - 0.02 13.5 0.0 0.026 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) DUF3353 PF11833.3 AEO66508.1 - 0.034 13.6 0.1 0.048 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Tmemb_cc2 PF10267.4 AEO66509.1 - 6.2 5.3 6.7 23 3.4 4.6 1.8 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein UDPGT PF00201.13 AEO66510.1 - 7.8e-06 24.6 0.0 1.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 AEO66510.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Ricin_B_lectin PF00652.17 AEO66511.1 - 9.8e-13 48.2 1.4 9.3e-12 45.0 1.0 1.9 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 AEO66511.1 - 1.5e-07 31.7 0.7 1.3e-05 25.5 0.3 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_76 PF03663.9 AEO66512.1 - 1.6e-118 396.2 5.0 2e-118 395.9 3.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 TRAPPC-Trs85 PF12739.2 AEO66512.1 - 0.059 12.0 1.0 0.089 11.4 0.7 1.2 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit APH PF01636.18 AEO66513.1 - 2.5e-17 63.4 0.2 2.6e-17 63.3 0.2 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO66513.1 - 5.2e-07 29.4 0.0 6.8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 AEO66513.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Gln-synt_C PF00120.19 AEO66514.1 - 2.9e-58 197.0 0.0 3.6e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 AEO66514.1 - 2.1e-20 72.0 0.0 3.6e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RNase_H PF00075.19 AEO66515.1 - 6.1e-09 36.3 0.0 1.4e-08 35.0 0.0 1.6 2 0 0 2 2 2 1 RNase H Abhydrolase_2 PF02230.11 AEO66516.1 - 4.7e-23 81.7 0.0 7.9e-22 77.7 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 AEO66516.1 - 2.9e-06 27.3 8.5 0.021 14.7 4.1 2.1 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO66516.1 - 3.4e-05 23.6 0.0 6.2e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO66516.1 - 0.065 12.4 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family LIP PF03583.9 AEO66516.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase HA2 PF04408.18 AEO66517.1 - 2.4e-29 101.3 0.1 5.1e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AEO66517.1 - 1.2e-27 96.0 0.0 2.2e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AEO66517.1 - 3.7e-12 45.9 0.0 8.4e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF482 PF04339.7 AEO66517.1 - 0.084 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF482 DEAD PF00270.24 AEO66517.1 - 0.087 12.3 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Pmp3 PF01679.12 AEO66518.1 - 2e-19 69.0 4.1 2.6e-19 68.6 2.8 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Arb1 PF09692.5 AEO66519.1 - 5.4e-119 397.5 0.0 1.1e-118 396.6 0.0 1.4 1 1 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.11 AEO66520.1 - 9.9e-57 191.7 0.0 1.3e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Clp1 PF06807.9 AEO66521.1 - 5.1e-25 88.3 0.0 7.7e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.12 AEO66521.1 - 1.5e-06 27.9 0.1 4.8e-06 26.2 0.1 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MobB PF03205.9 AEO66521.1 - 7.4e-06 25.7 0.0 1.7e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 AEO66521.1 - 1.7e-05 24.8 0.0 5.8e-05 23.1 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain AAA_19 PF13245.1 AEO66521.1 - 4.2e-05 23.2 2.7 4.2e-05 23.2 1.9 2.4 2 1 0 2 2 1 1 Part of AAA domain AAA_33 PF13671.1 AEO66521.1 - 0.00014 21.7 0.2 0.00031 20.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 AEO66521.1 - 0.00015 21.2 0.1 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_17 PF13207.1 AEO66521.1 - 0.00023 21.9 0.1 0.00084 20.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_10 PF12846.2 AEO66521.1 - 0.00078 18.9 0.1 0.0016 17.9 0.0 1.5 2 0 0 2 2 2 1 AAA-like domain MMR_HSR1 PF01926.18 AEO66521.1 - 0.00096 19.0 0.0 0.0078 16.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AEO66521.1 - 0.0012 18.6 0.0 0.054 13.3 0.0 2.3 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.1 AEO66521.1 - 0.0015 18.6 0.0 0.004 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 AEO66521.1 - 0.0015 17.9 0.1 0.0057 16.1 0.0 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain KTI12 PF08433.5 AEO66521.1 - 0.0021 17.3 0.1 0.012 14.8 0.0 1.9 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA PF00004.24 AEO66521.1 - 0.0026 17.9 0.4 0.0094 16.1 0.1 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 AEO66521.1 - 0.0029 17.2 0.5 0.027 14.0 0.0 2.5 2 1 1 3 3 3 1 AAA domain ArgK PF03308.11 AEO66521.1 - 0.003 16.3 0.4 0.006 15.4 0.3 1.4 1 0 0 1 1 1 1 ArgK protein AAA_28 PF13521.1 AEO66521.1 - 0.0032 17.4 0.1 0.0082 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO66521.1 - 0.0034 17.6 0.0 0.0068 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 AEO66521.1 - 0.0036 16.7 0.1 0.016 14.6 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 AEO66521.1 - 0.0075 15.9 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 AEO66521.1 - 0.02 15.1 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 AEO66521.1 - 0.044 12.8 0.3 0.33 10.0 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.10 AEO66521.1 - 0.045 13.4 0.1 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 NTPase Mg_chelatase PF01078.16 AEO66521.1 - 0.052 12.6 0.3 0.11 11.6 0.1 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 AEO66521.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.18 AEO66521.1 - 0.069 12.5 0.5 0.36 10.1 0.1 1.9 1 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 AEO66521.1 - 0.092 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Miro PF08477.8 AEO66521.1 - 0.1 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 AEO66521.1 - 0.11 12.1 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.7 AEO66521.1 - 0.13 11.3 0.4 1.2 8.1 0.1 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 AEO66521.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.10 AEO66521.1 - 0.22 10.1 0.1 0.34 9.5 0.1 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NmrA PF05368.8 AEO66522.1 - 1.5e-32 112.7 0.0 1.8e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO66522.1 - 5.3e-20 72.1 0.0 7.1e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 AEO66522.1 - 0.0036 17.2 0.0 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 AEO66522.1 - 0.0045 16.4 0.0 0.12 11.7 0.0 2.7 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO66522.1 - 0.14 10.8 0.0 0.34 9.5 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family VIT1 PF01988.14 AEO66523.1 - 9.6e-12 44.8 1.8 1.2e-11 44.5 1.2 1.0 1 0 0 1 1 1 1 VIT family Phosphoesterase PF04185.9 AEO66524.1 - 2.3e-32 112.6 2.6 1.5e-31 109.9 1.7 1.9 1 1 0 1 1 1 1 Phosphoesterase family Polysacc_deac_1 PF01522.16 AEO66524.1 - 0.012 15.2 0.1 0.2 11.3 0.0 2.7 3 0 0 3 3 3 0 Polysaccharide deacetylase PI3K_rbd PF00794.13 AEO66524.1 - 0.016 15.0 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain Sulfatase PF00884.18 AEO66524.1 - 0.025 13.7 0.1 0.037 13.2 0.1 1.4 1 0 0 1 1 1 0 Sulfatase Git3 PF11710.3 AEO66526.1 - 5.8e-64 215.3 16.0 3.5e-62 209.5 11.3 2.1 2 0 0 2 2 2 2 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 AEO66526.1 - 5.1e-25 87.0 1.2 6.6e-24 83.4 0.0 2.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 AEO66526.1 - 4.6e-05 22.6 5.9 0.00023 20.3 3.3 2.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GATase PF00117.23 AEO66527.1 - 6.6e-11 42.0 0.0 8.7e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Acetyltransf_6 PF13480.1 AEO66527.1 - 0.1 12.5 0.9 0.28 11.1 0.3 2.0 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain DHHA2 PF02833.9 AEO66528.1 - 2.5e-19 69.7 0.0 4.5e-10 39.8 0.0 2.2 2 0 0 2 2 2 2 DHHA2 domain DHH PF01368.15 AEO66528.1 - 4.1e-09 36.2 0.0 7.3e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 DHH family DUF2968 PF11180.3 AEO66528.1 - 0.016 14.5 4.7 0.029 13.7 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Orthopox_F8 PF05886.6 AEO66528.1 - 0.2 11.5 1.0 0.39 10.5 0.7 1.5 1 0 0 1 1 1 0 Orthopoxvirus F8 protein Oligomerisation PF02410.10 AEO66529.1 - 0.0016 18.4 0.0 0.015 15.3 0.0 2.4 1 1 0 1 1 1 1 Oligomerisation domain PPR_3 PF13812.1 AEO66529.1 - 0.0036 17.4 0.1 0.59 10.5 0.0 3.5 3 0 0 3 3 3 1 Pentatricopeptide repeat domain RNA_pol PF00940.14 AEO66530.1 - 5.6e-165 548.7 0.0 8e-165 548.2 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 AEO66530.1 - 5e-78 262.5 1.0 5e-78 262.5 0.7 2.2 3 0 0 3 3 3 1 DNA-directed RNA polymerase N-terminal tRNA_bind PF01588.15 AEO66532.1 - 8.9e-24 83.1 0.6 8.8e-23 79.9 0.4 2.2 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 AEO66532.1 - 1.6e-06 28.4 0.6 3.7e-06 27.3 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 AEO66532.1 - 7.2e-05 22.5 0.1 0.00016 21.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AEO66532.1 - 0.015 15.2 1.7 0.023 14.6 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Rotamase_2 PF13145.1 AEO66532.1 - 8.7 7.0 14.2 1.3 9.6 5.9 2.3 2 0 0 2 2 2 0 PPIC-type PPIASE domain SNF2_N PF00176.18 AEO66533.1 - 2.2e-71 240.1 0.2 4.2e-71 239.1 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO66533.1 - 3.7e-17 61.9 0.2 1.6e-16 59.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO66533.1 - 1.7e-06 27.9 0.0 9.5e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ribosomal_60s PF00428.14 AEO66535.1 - 4 7.9 15.1 0.23 11.8 4.3 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Sld5 PF05916.6 AEO66536.1 - 7.1e-23 80.9 0.0 1.3e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Ribosomal_60s PF00428.14 AEO66536.1 - 2 8.8 11.6 0.23 11.9 2.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-C2H2 PF00096.21 AEO66537.1 - 1.3e-08 34.6 6.9 3.2e-05 23.9 1.0 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO66537.1 - 1e-07 31.7 7.8 0.00075 19.6 1.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 AEO66537.1 - 7.7e-07 29.1 0.9 0.0061 16.6 0.1 2.1 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 AEO66537.1 - 0.011 15.9 0.5 0.52 10.5 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 AEO66537.1 - 0.021 14.9 1.1 2.2 8.4 0.2 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Lar_restr_allev PF14354.1 AEO66537.1 - 0.023 15.0 0.1 0.03 14.6 0.1 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF968 PF06147.6 AEO66537.1 - 0.031 14.2 3.8 2.7 7.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF968) zf-BED PF02892.10 AEO66537.1 - 0.071 12.8 1.7 0.071 12.8 1.2 2.6 2 1 0 2 2 2 0 BED zinc finger zf-ribbon_3 PF13248.1 AEO66537.1 - 0.092 11.9 0.7 5.2 6.4 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-DBF PF07535.7 AEO66537.1 - 0.19 11.4 1.3 2.8 7.6 0.1 2.2 2 0 0 2 2 2 0 DBF zinc finger UPF0547 PF10571.4 AEO66537.1 - 0.21 11.2 2.2 13 5.6 0.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 ADK_lid PF05191.9 AEO66537.1 - 0.3 10.7 3.9 0.59 9.8 0.8 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid FYVE PF01363.16 AEO66537.1 - 0.69 9.8 3.2 3.1 7.7 2.2 1.9 1 1 0 1 1 1 0 FYVE zinc finger zf-C2HC_2 PF13913.1 AEO66537.1 - 0.93 9.2 8.5 2 8.1 0.2 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-met2 PF12907.2 AEO66537.1 - 0.97 9.4 6.8 6.4 6.8 0.1 2.8 2 1 0 2 2 2 0 Zinc-binding DUF4448 PF14610.1 AEO66539.1 - 1.8e-20 73.2 0.0 4.6e-20 71.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Rhodanese PF00581.15 AEO66542.1 - 6.2e-15 55.5 0.1 2.1e-11 44.1 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain UPF0121 PF03661.8 AEO66544.1 - 1.7e-12 47.1 0.2 2.8e-12 46.3 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) YGGT PF02325.12 AEO66544.1 - 0.089 12.7 0.4 0.089 12.7 0.3 3.0 3 1 1 4 4 4 0 YGGT family FA_desaturase PF00487.19 AEO66544.1 - 6.4 6.1 12.3 13 5.1 7.3 2.2 1 1 0 1 1 1 0 Fatty acid desaturase DSPc PF00782.15 AEO66545.1 - 3.7e-10 39.5 0.0 7.4e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AEO66545.1 - 0.018 14.4 0.4 0.048 12.9 0.1 1.7 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 AEO66545.1 - 0.028 14.6 0.3 0.053 13.7 0.2 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Pribosyltran_N PF13793.1 AEO66546.1 - 4.8e-43 145.5 0.9 5.3e-42 142.2 0.1 2.7 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 AEO66546.1 - 1.5e-40 138.9 2.8 6e-36 123.9 0.2 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 AEO66546.1 - 6.3e-13 48.5 0.3 2.1e-12 46.8 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AEO66546.1 - 0.0023 17.1 0.7 0.0042 16.3 0.2 1.6 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase DUF218 PF02698.12 AEO66546.1 - 0.071 12.6 0.1 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 DUF218 domain AF2331-like PF14556.1 AEO66546.1 - 0.1 12.9 0.6 4.5 7.6 0.0 2.9 3 0 0 3 3 3 0 AF2331-like Alpha_kinase PF02816.13 AEO66547.1 - 1.6e-40 138.8 0.0 1.9e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Ank_2 PF12796.2 AEO66549.1 - 7.9e-33 112.6 0.0 8e-22 77.3 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AEO66549.1 - 6.1e-32 109.4 3.5 1.8e-11 44.2 0.7 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO66549.1 - 2.2e-28 97.6 2.9 3.4e-09 36.6 0.2 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 AEO66549.1 - 2.3e-24 83.9 0.0 9.2e-07 28.3 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 AEO66549.1 - 3.2e-24 82.5 0.0 2.3e-06 27.2 0.1 5.2 5 0 0 5 5 5 4 Ankyrin repeat DUF3734 PF12536.3 AEO66549.1 - 0.078 13.0 0.0 6.4 6.9 0.0 2.6 1 1 2 3 3 3 0 Patatin phospholipase APH PF01636.18 AEO66552.1 - 1.1e-13 51.4 0.1 2.9e-11 43.5 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO66552.1 - 1.7e-09 37.5 0.0 2.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 AEO66552.1 - 0.0099 14.8 0.0 0.029 13.3 0.0 1.6 2 0 0 2 2 2 1 Fructosamine kinase EcKinase PF02958.15 AEO66552.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Gal-3-0_sulfotr PF06990.6 AEO66553.1 - 0.14 10.8 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase DUF566 PF04484.7 AEO66554.1 - 1.3 8.4 4.4 1.9 7.9 3.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) MRI PF15325.1 AEO66554.1 - 2 9.4 13.9 0.95 10.4 0.5 2.7 2 1 1 3 3 3 0 Modulator of retrovirus infection DUF3474 PF11960.3 AEO66554.1 - 2.5 8.1 6.7 2.4 8.1 0.7 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF3474) DUF3464 PF11947.3 AEO66554.1 - 4.5 6.7 9.0 7.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Abhydrolase_3 PF07859.8 AEO66555.1 - 8.7e-21 74.4 1.1 2.6e-20 72.8 0.8 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO66555.1 - 1.1e-08 34.9 0.1 1.6e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO66555.1 - 2.5e-06 27.5 5.7 4.5e-06 26.7 4.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 AEO66555.1 - 9.4e-05 21.3 0.1 0.00079 18.2 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase PF07224.6 AEO66555.1 - 0.00015 20.7 0.0 0.00023 20.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 AEO66555.1 - 0.00023 20.1 0.1 0.00037 19.4 0.1 1.3 1 1 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.15 AEO66555.1 - 0.00025 20.5 0.1 0.0006 19.3 0.0 1.8 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.7 AEO66555.1 - 0.00049 18.7 0.1 0.24 9.8 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 AEO66555.1 - 0.00066 18.9 0.0 0.034 13.3 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 AEO66555.1 - 0.0026 17.0 0.0 0.22 10.7 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF2305 PF10230.4 AEO66555.1 - 0.18 11.1 0.0 4.5 6.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) DUF4238 PF14022.1 AEO66556.1 - 8.1e-35 120.3 0.1 1.1e-34 119.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Cytochrom_B561 PF03188.11 AEO66557.1 - 3.5e-05 23.6 7.3 7.5e-05 22.5 5.1 1.5 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF805 PF05656.9 AEO66557.1 - 0.079 12.7 15.9 0.24 11.2 3.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF805) Ni_hydr_CYTB PF01292.15 AEO66557.1 - 0.15 11.3 12.9 1.1 8.6 9.1 2.0 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF3816 PF12822.2 AEO66557.1 - 0.16 11.8 6.4 0.21 11.4 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) NfeD PF01957.13 AEO66557.1 - 0.3 11.2 7.4 0.26 11.4 2.4 2.4 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding YtpI PF14007.1 AEO66557.1 - 0.53 10.2 3.0 0.41 10.5 0.1 2.2 2 1 0 2 2 2 0 YtpI-like protein DUF2306 PF10067.4 AEO66557.1 - 1.8 8.7 16.0 0.059 13.4 2.3 2.9 1 1 1 3 3 3 0 Predicted membrane protein (DUF2306) DUF2427 PF10348.4 AEO66557.1 - 2.9 7.5 16.7 0.92 9.1 2.0 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF2427) DUF202 PF02656.10 AEO66557.1 - 3.8 7.8 15.1 2.4 8.4 2.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Prok-RING_2 PF14445.1 AEO66558.1 - 0.044 13.7 0.5 0.044 13.7 0.3 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 DUF2072 PF09845.4 AEO66558.1 - 0.049 13.5 0.6 0.076 12.9 0.3 1.3 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Glyco_hydro_72 PF03198.9 AEO66559.1 - 2.7e-116 387.9 4.0 3.8e-116 387.4 2.8 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 AEO66559.1 - 7.4e-07 28.6 0.8 1.6e-06 27.5 0.6 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HAUS6_N PF14661.1 AEO66561.1 - 6.4e-63 212.3 1.1 6.4e-63 212.3 0.7 1.6 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Herpes_capsid PF06112.6 AEO66561.1 - 4 7.4 11.4 0.5 10.3 2.6 2.8 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Ribosomal_S21 PF01165.15 AEO66562.1 - 4.1e-09 35.7 4.5 6.6e-09 35.0 3.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 PWI PF01480.12 AEO66563.1 - 3.2e-09 36.7 0.3 6.9e-09 35.6 0.2 1.6 1 0 0 1 1 1 1 PWI domain Sensor PF13796.1 AEO66563.1 - 1.7 8.2 3.2 4.6 6.8 2.2 1.7 1 0 0 1 1 1 0 Putative sensor ECH PF00378.15 AEO66564.1 - 1.6e-33 115.8 0.2 7e-32 110.4 0.2 2.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Serglycin PF04360.7 AEO66566.1 - 2 8.1 6.8 2.7 7.6 4.7 1.3 1 0 0 1 1 1 0 Serglycin AAA PF00004.24 AEO66567.1 - 5.2e-41 139.9 0.0 1.1e-40 138.8 0.0 1.5 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 AEO66567.1 - 2.9e-19 68.6 0.2 3.2e-18 65.3 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 AEO66567.1 - 1.6e-07 31.5 0.1 0.0015 18.6 0.0 2.9 1 1 2 3 3 3 2 AAA domain RuvB_N PF05496.7 AEO66567.1 - 4.3e-07 29.2 0.0 1.8e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AEO66567.1 - 1.8e-06 28.0 0.7 0.0001 22.3 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 AEO66567.1 - 3.9e-06 27.6 0.0 7.5e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO66567.1 - 4.8e-06 26.3 0.0 9.5e-05 22.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 AEO66567.1 - 7.4e-06 25.5 0.1 0.017 14.5 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_14 PF13173.1 AEO66567.1 - 1.1e-05 25.3 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AEO66567.1 - 4.7e-05 22.8 0.0 0.00012 21.5 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF815 PF05673.8 AEO66567.1 - 4.8e-05 22.4 0.0 7.8e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 AEO66567.1 - 6.4e-05 21.8 0.0 9.7e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 AEO66567.1 - 0.00045 20.1 0.0 0.00077 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) KaiC PF06745.8 AEO66567.1 - 0.00051 19.2 0.0 0.14 11.2 0.0 2.3 1 1 1 2 2 2 1 KaiC Zeta_toxin PF06414.7 AEO66567.1 - 0.00063 18.9 0.0 0.0015 17.7 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 AEO66567.1 - 0.00077 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 AEO66567.1 - 0.0015 18.4 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 AEO66567.1 - 0.0025 16.7 0.0 0.0041 16.0 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_18 PF13238.1 AEO66567.1 - 0.0061 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 AEO66567.1 - 0.0072 15.9 0.0 0.25 11.0 0.0 2.3 1 1 1 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 AEO66567.1 - 0.0078 15.9 0.1 0.2 11.3 0.0 2.2 1 1 1 2 2 2 1 Archaeal ATPase AAA_24 PF13479.1 AEO66567.1 - 0.009 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO66567.1 - 0.01 15.5 1.6 0.024 14.4 0.0 2.3 2 1 0 2 2 2 0 Part of AAA domain Mg_chelatase PF01078.16 AEO66567.1 - 0.011 14.9 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 AEO66567.1 - 0.015 15.3 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 AEO66567.1 - 0.025 13.7 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein PPV_E1_C PF00519.12 AEO66567.1 - 0.038 12.6 0.0 0.046 12.3 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AAA_30 PF13604.1 AEO66567.1 - 0.053 13.1 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 AEO66567.1 - 0.068 12.6 0.0 0.28 10.6 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain T2SE PF00437.15 AEO66567.1 - 0.099 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Peptidase_M28 PF04389.12 AEO66567.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M28 AAA_28 PF13521.1 AEO66567.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 AEO66567.1 - 0.15 11.9 0.1 2.4 8.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 AEO66567.1 - 0.17 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase KAP_NTPase PF07693.9 AEO66567.1 - 0.17 10.8 0.1 7.3 5.4 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain Mito_carr PF00153.22 AEO66568.1 - 3.7e-57 190.0 6.4 1.2e-19 69.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIIC_delta PF12657.2 AEO66569.1 - 3.1e-17 62.8 0.0 2.4e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 AEO66569.1 - 1.1e-09 38.0 0.5 2.3e-09 37.0 0.3 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Peptidase_C13 PF01650.13 AEO66570.1 - 9.9e-42 142.9 0.1 1.4e-41 142.5 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Spc24 PF08286.6 AEO66570.1 - 0.4 10.3 4.3 0.77 9.4 3.0 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 His_Phos_1 PF00300.17 AEO66571.1 - 4.1e-08 33.4 0.0 7.6e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.11 AEO66572.1 - 3.8e-11 42.3 31.6 3.8e-11 42.3 21.9 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily F-box-like PF12937.2 AEO66573.1 - 0.0071 16.0 0.2 0.019 14.6 0.0 1.8 2 0 0 2 2 2 1 F-box-like Acetyltransf_1 PF00583.19 AEO66574.1 - 7.6e-05 22.6 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AEO66574.1 - 0.0093 16.0 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO66574.1 - 0.07 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Baculo_ME53 PF06061.6 AEO66575.1 - 0.0022 17.0 0.3 0.0037 16.2 0.2 1.3 1 0 0 1 1 1 1 Baculoviridae ME53 Gly_transf_sug PF04488.10 AEO66576.1 - 3e-09 37.1 0.0 4.7e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Ank_2 PF12796.2 AEO66577.1 - 1.9e-53 178.7 4.5 5.8e-14 52.2 0.0 5.9 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 AEO66577.1 - 1.2e-36 122.7 18.5 1e-08 34.5 0.1 10.0 10 0 0 10 10 10 6 Ankyrin repeat Ank_3 PF13606.1 AEO66577.1 - 1.8e-30 101.9 8.0 3e-05 23.8 0.0 9.4 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 AEO66577.1 - 4.6e-28 97.0 5.5 3.6e-07 30.5 0.0 8.8 4 3 5 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO66577.1 - 5.2e-26 90.0 10.9 8.1e-10 38.6 0.2 8.1 4 4 4 8 8 8 4 Ankyrin repeats (many copies) SPRY PF00622.23 AEO66577.1 - 1.5e-13 50.8 0.0 2.8e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 SPRY domain NACHT PF05729.7 AEO66577.1 - 5.8e-07 29.3 0.0 2.9e-06 27.0 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 AEO66577.1 - 1.5e-05 25.0 1.4 9e-05 22.5 0.2 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AEO66577.1 - 0.027 14.6 0.0 0.098 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 AEO66577.1 - 0.081 12.5 0.1 13 5.3 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.17 AEO66577.1 - 0.26 11.5 0.0 0.52 10.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 AEO66577.1 - 0.27 10.0 0.0 0.58 8.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Cation_efflux PF01545.16 AEO66578.1 - 9.8e-63 211.8 0.6 1.3e-62 211.4 0.4 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 AEO66578.1 - 0.0049 15.9 36.2 0.0096 14.9 11.0 2.9 2 1 0 2 2 2 2 ZIP Zinc transporter ESSS PF10183.4 AEO66578.1 - 6 7.3 14.1 8 6.9 1.7 3.9 3 1 1 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) UQ_con PF00179.21 AEO66579.1 - 3.2e-37 127.0 0.0 3.8e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO66579.1 - 0.0012 18.6 0.1 0.0028 17.3 0.1 1.6 1 1 1 2 2 2 1 Prokaryotic E2 family B Nop14 PF04147.7 AEO66580.1 - 0.15 9.9 12.1 0.25 9.2 8.4 1.3 1 0 0 1 1 1 0 Nop14-like family PBP_sp32 PF07222.7 AEO66580.1 - 0.16 11.1 4.1 0.28 10.3 2.9 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pox_Ag35 PF03286.9 AEO66580.1 - 0.68 9.4 19.2 0.021 14.3 6.5 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF3246 PF11596.3 AEO66580.1 - 1.6 7.9 4.7 0.22 10.7 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) PBP1_TM PF14812.1 AEO66580.1 - 2.8 8.3 26.8 0.19 12.0 3.2 3.0 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC27 PF09507.5 AEO66580.1 - 2.8 7.0 25.2 0.31 10.2 7.2 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 PGA2 PF07543.7 AEO66580.1 - 5.1 6.8 14.9 2.3 7.9 8.1 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 zf-C2H2_jaz PF12171.3 AEO66581.1 - 6e-07 29.4 0.3 1e-06 28.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1777 PF08648.7 AEO66581.1 - 1.2e-05 25.1 13.3 1.2e-05 25.1 9.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-met PF12874.2 AEO66581.1 - 3.9e-05 23.6 0.4 6.7e-05 22.9 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 AEO66581.1 - 0.031 13.9 0.1 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 DBF zinc finger DUF3268 PF11672.3 AEO66581.1 - 0.13 12.3 0.8 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) DUF3332 PF11810.3 AEO66581.1 - 0.21 11.2 1.3 0.44 10.1 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) AKAP95 PF04988.7 AEO66581.1 - 0.54 10.0 0.0 0.54 10.0 0.0 2.3 1 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Pyridox_oxidase PF01243.15 AEO66582.1 - 4.2e-07 29.8 0.0 6.7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Glyco_hydro_92 PF07971.7 AEO66584.1 - 7.9e-170 565.7 0.0 9.7e-170 565.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 TP_methylase PF00590.15 AEO66585.1 - 7.2e-13 48.7 0.0 1.3e-12 47.8 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PAS_9 PF13426.1 AEO66586.1 - 1.2e-13 51.3 0.0 6.4e-13 48.9 0.0 2.2 3 0 0 3 3 3 1 PAS domain RGS PF00615.14 AEO66586.1 - 3e-05 24.0 0.0 5.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS PF00989.19 AEO66586.1 - 3.9e-05 23.4 0.0 0.00091 18.9 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.5 AEO66586.1 - 0.008 16.1 0.2 2.1 8.4 0.0 2.9 3 0 0 3 3 3 2 PAS fold Lactamase_B_2 PF12706.2 AEO66587.1 - 2.8e-41 141.2 0.0 3.6e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AEO66587.1 - 2.6e-10 40.2 0.0 4.9e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AEO66587.1 - 2.6e-06 27.2 0.7 3.2e-05 23.6 0.2 2.6 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Polyketide_cyc2 PF10604.4 AEO66589.1 - 4.3e-06 26.9 0.5 5.1e-06 26.7 0.4 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport TAT_signal PF10518.4 AEO66589.1 - 0.12 12.4 0.1 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Glycophorin_A PF01102.13 AEO66590.1 - 0.0014 18.3 1.1 0.0031 17.2 0.7 1.6 1 0 0 1 1 1 1 Glycophorin A Podoplanin PF05808.6 AEO66590.1 - 0.0041 16.6 12.2 0.0069 15.9 8.4 1.4 1 1 0 1 1 1 1 Podoplanin DUF1275 PF06912.6 AEO66590.1 - 0.006 15.7 5.6 0.01 15.0 3.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) SKG6 PF08693.5 AEO66590.1 - 0.015 14.6 0.3 0.048 12.9 0.2 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain IncA PF04156.9 AEO66590.1 - 0.02 14.5 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 IncA protein Sporozoite_P67 PF05642.6 AEO66590.1 - 0.11 10.3 10.7 0.15 9.9 7.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Syndecan PF01034.15 AEO66590.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Pex14_N PF04695.8 AEO66590.1 - 0.96 9.5 10.6 0.32 11.0 5.1 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 AEO66590.1 - 4.8 5.3 9.9 6.5 4.9 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein ABC_tran PF00005.22 AEO66591.1 - 1.4e-43 148.5 0.3 6.1e-25 88.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 AEO66591.1 - 2.5e-38 132.0 12.3 4e-22 78.9 5.9 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 AEO66591.1 - 3.1e-10 39.6 0.4 0.00042 19.6 0.0 4.0 2 2 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AEO66591.1 - 5.4e-08 33.0 1.0 0.0083 16.1 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.1 AEO66591.1 - 3.5e-07 30.4 0.0 1.4 8.8 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 AEO66591.1 - 4.1e-07 30.1 0.4 0.0048 17.0 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 AEO66591.1 - 1.6e-05 24.4 0.2 0.0065 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 AEO66591.1 - 2.2e-05 24.1 0.1 0.034 13.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain T2SE PF00437.15 AEO66591.1 - 3.3e-05 22.9 0.1 0.061 12.2 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 AEO66591.1 - 5.6e-05 22.5 1.9 0.0069 15.8 0.3 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain DUF258 PF03193.11 AEO66591.1 - 7.6e-05 21.9 0.1 0.026 13.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 AEO66591.1 - 0.00019 21.9 0.1 0.049 14.1 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 AEO66591.1 - 0.0002 20.9 0.5 0.12 11.8 0.0 3.4 3 0 0 3 3 3 1 AAA-like domain FtsK_SpoIIIE PF01580.13 AEO66591.1 - 0.00055 19.4 0.1 0.025 14.0 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 AEO66591.1 - 0.00064 20.1 3.9 0.084 13.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.10 AEO66591.1 - 0.0022 17.7 0.8 1.2 8.7 0.1 2.8 2 0 0 2 2 2 1 NTPase MobB PF03205.9 AEO66591.1 - 0.023 14.3 0.4 3 7.5 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 AEO66591.1 - 0.027 14.1 0.0 0.58 9.8 0.0 2.7 3 0 0 3 3 3 0 Archaeal ATPase SbcCD_C PF13558.1 AEO66591.1 - 0.029 14.3 0.0 8.9 6.3 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 AEO66591.1 - 0.029 15.2 0.1 0.3 11.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 AEO66591.1 - 0.057 13.2 0.1 0.18 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 AEO66591.1 - 0.064 13.2 0.0 3 7.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.24 AEO66591.1 - 0.064 13.4 0.0 5 7.3 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 AEO66591.1 - 0.074 13.3 1.2 1.2 9.4 0.4 2.8 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.1 AEO66591.1 - 0.081 12.6 3.4 3.5 7.4 0.4 3.2 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 AEO66591.1 - 0.098 12.8 0.1 28 4.9 0.0 2.8 3 0 0 3 3 2 0 RNA helicase DUF2075 PF09848.4 AEO66591.1 - 0.1 11.5 0.4 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 AEO66591.1 - 0.16 11.3 2.6 1.9 7.9 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 AEO66591.1 - 0.23 11.0 2.6 1.6 8.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 AEO66591.1 - 0.31 10.3 0.3 5.5 6.2 0.1 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein IstB_IS21 PF01695.12 AEO66591.1 - 0.35 10.2 3.3 2.5 7.5 0.2 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein Dynamin_N PF00350.18 AEO66591.1 - 0.63 9.8 5.5 5.3 6.8 0.1 3.0 3 0 0 3 3 3 0 Dynamin family Hid1 PF12722.2 AEO66591.1 - 1.9 6.0 5.4 2.8 5.4 3.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM196 PF15265.1 AEO66592.1 - 0.5 9.5 18.2 0.58 9.3 12.6 1.1 1 0 0 1 1 1 0 FAM196 family Hid1 PF12722.2 AEO66592.1 - 0.72 7.4 11.7 0.95 7.0 8.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.8 AEO66592.1 - 7.4 6.3 12.9 10 5.8 8.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit p450 PF00067.17 AEO66593.1 - 2.7e-51 174.5 0.0 3.8e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LIP PF03583.9 AEO66594.1 - 2.1e-64 217.5 0.5 3e-64 217.0 0.3 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.16 AEO66594.1 - 0.056 12.6 0.4 0.11 11.6 0.2 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pkinase PF00069.20 AEO66595.1 - 4.9e-71 238.9 0.0 6.7e-71 238.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO66595.1 - 9.2e-34 116.6 0.0 1.3e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 AEO66595.1 - 1.1e-06 29.0 0.5 1.1e-06 29.0 0.3 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 AEO66595.1 - 0.0011 18.0 0.0 0.0022 17.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AEO66595.1 - 0.054 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PGI PF00342.14 AEO66596.1 - 2.1e-209 695.9 0.2 2.4e-209 695.7 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase CUE PF02845.11 AEO66597.1 - 4.9e-06 25.9 0.0 7.5e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain Imm45 PF15603.1 AEO66598.1 - 0.11 12.6 0.0 3.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 45 NUDE_C PF04880.8 AEO66599.1 - 1.5 9.1 5.8 8.6 6.6 3.2 2.1 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region DUF515 PF04415.7 AEO66599.1 - 4.9 5.2 5.4 6.6 4.8 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) GMC_oxred_N PF00732.14 AEO66600.1 - 1.5e-37 129.3 0.0 2e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO66600.1 - 3.5e-28 98.7 0.1 7.7e-28 97.6 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Cyt-b5 PF00173.23 AEO66601.1 - 4.4e-13 48.8 0.0 5.6e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FoP_duplication PF13865.1 AEO66602.1 - 0.46 10.9 2.2 0.3 11.5 0.3 1.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 SMAP PF15477.1 AEO66602.1 - 1.3 9.3 4.8 1.7 8.9 3.3 1.5 1 1 0 1 1 1 0 Small acidic protein family Ank_2 PF12796.2 AEO66603.1 - 1e-05 25.7 0.0 0.00016 21.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AEO66603.1 - 6.1e-05 22.6 0.1 0.08 12.7 0.2 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 AEO66603.1 - 0.02 15.4 0.0 0.15 12.6 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) MOZART1 PF12554.3 AEO66603.1 - 0.082 12.3 0.1 0.75 9.3 0.0 2.1 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated Ank_5 PF13857.1 AEO66603.1 - 0.13 12.5 0.1 2.4 8.5 0.1 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) VPS9 PF02204.13 AEO66604.1 - 4.1e-31 107.0 0.1 1e-30 105.7 0.1 1.7 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 AEO66604.1 - 5.7e-10 38.4 0.0 3.8e-08 32.6 0.0 3.2 3 0 0 3 3 3 1 CUE domain BRCA-2_helical PF09169.5 AEO66605.1 - 0.084 12.4 0.6 0.12 11.9 0.4 1.2 1 0 0 1 1 1 0 BRCA2, helical Avl9 PF09794.4 AEO66605.1 - 0.087 11.2 0.1 0.21 9.9 0.0 1.6 2 0 0 2 2 2 0 Transport protein Avl9 Asn_synthase PF00733.16 AEO66606.1 - 8.7e-57 192.5 0.0 1.1e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 AEO66606.1 - 7.8e-08 32.0 0.0 5.8e-07 29.2 0.0 2.4 2 2 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 AEO66606.1 - 7.8e-05 22.6 0.0 0.00021 21.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain Glyco_hydro_18 PF00704.23 AEO66607.1 - 6.5e-43 147.4 0.0 2.5e-42 145.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 AEO66607.1 - 3.5e-12 46.0 0.6 7.4e-06 25.7 0.4 3.1 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.14 AEO66607.1 - 4.3e-05 23.4 3.4 4.3e-05 23.4 2.4 3.0 3 0 0 3 3 3 1 Chitin recognition protein DUF3142 PF11340.3 AEO66607.1 - 0.00028 20.5 0.0 0.00055 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) DUF543 PF04418.7 AEO66609.1 - 0.087 12.7 0.2 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Herpes_gE PF02480.11 AEO66610.1 - 2.7e-05 22.6 0.0 3.8e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E RELT PF12606.3 AEO66610.1 - 0.004 16.2 0.5 0.0071 15.4 0.3 1.3 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 EphA2_TM PF14575.1 AEO66610.1 - 0.018 15.3 0.0 0.032 14.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SCIMP PF15050.1 AEO66610.1 - 0.027 14.3 0.7 0.054 13.3 0.5 1.6 1 1 0 1 1 1 0 SCIMP protein DUF1191 PF06697.7 AEO66610.1 - 0.032 13.0 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Orthoreo_P10 PF07204.6 AEO66610.1 - 0.04 13.6 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Ly49 PF08391.5 AEO66610.1 - 0.064 13.3 0.7 0.089 12.9 0.5 1.4 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region CD34_antigen PF06365.7 AEO66610.1 - 0.074 12.6 0.2 0.13 11.9 0.1 1.4 1 1 0 1 1 1 0 CD34/Podocalyxin family TRP PF06011.7 AEO66610.1 - 0.091 11.3 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel IncA PF04156.9 AEO66610.1 - 0.44 10.1 6.9 1.6 8.3 4.6 1.8 1 1 0 1 1 1 0 IncA protein TMEM51 PF15345.1 AEO66610.1 - 0.49 10.0 3.3 0.13 11.9 0.3 1.7 1 1 0 1 1 1 0 Transmembrane protein 51 TFIIB PF00382.14 AEO66611.1 - 1e-35 121.3 0.7 6.6e-20 70.6 0.2 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AEO66611.1 - 1.6e-14 52.9 0.7 2.7e-14 52.2 0.5 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 AEO66611.1 - 0.0079 16.1 0.0 0.13 12.1 0.0 2.4 1 1 1 2 2 2 1 Cyclin, C-terminal domain Lipoprotein_6 PF01441.14 AEO66611.1 - 0.0092 15.8 1.0 0.015 15.1 0.7 1.3 1 0 0 1 1 1 1 Lipoprotein zf-ribbon_3 PF13248.1 AEO66611.1 - 1.1 8.5 3.5 0.67 9.2 0.6 2.0 2 0 0 2 2 2 0 zinc-ribbon domain CRC_subunit PF08624.5 AEO66612.1 - 3.5e-59 198.7 0.0 4.8e-59 198.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Nop14 PF04147.7 AEO66612.1 - 4.2 5.1 7.8 6.9 4.4 5.4 1.2 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.22 AEO66614.1 - 4.6e-05 22.8 0.3 4.6e-05 22.8 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Plasmod_dom_1 PF09715.5 AEO66614.1 - 1.1 9.2 5.4 0.19 11.7 0.6 2.1 2 1 1 3 3 3 0 Plasmodium protein of unknown function (Plasmod_dom_1) Cyclin PF08613.6 AEO66615.1 - 2.7e-14 53.8 0.0 4e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin DUF221 PF02714.10 AEO66615.1 - 0.0054 15.6 0.0 0.008 15.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 Cyclin_N PF00134.18 AEO66615.1 - 0.048 13.2 0.2 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Cyclin, N-terminal domain Nefa_Nip30_N PF10187.4 AEO66616.1 - 6.5e-23 80.8 13.0 1.7e-22 79.4 9.0 1.7 1 1 1 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Med3 PF11593.3 AEO66616.1 - 0.082 12.1 3.1 0.12 11.5 2.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Dicty_REP PF05086.7 AEO66616.1 - 0.43 8.2 2.0 0.53 7.9 1.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tim54 PF11711.3 AEO66617.1 - 2.5e-127 424.6 0.8 4e-127 423.9 0.6 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.20 AEO66618.1 - 2.9e-56 190.4 0.2 8.5e-40 136.5 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO66618.1 - 9e-27 93.7 0.1 6.4e-21 74.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AEO66618.1 - 0.00011 21.3 0.0 0.00022 20.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO66618.1 - 0.00014 21.6 0.2 0.019 14.6 0.1 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO66618.1 - 0.00064 18.8 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 AEO66618.1 - 0.033 14.7 0.5 0.12 12.9 0.4 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 AEO66618.1 - 0.039 12.7 0.1 0.061 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 AEO66618.1 - 0.069 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 AEO66618.1 - 0.18 11.1 2.8 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 RIO1 family zf-met PF12874.2 AEO66619.1 - 5.4e-06 26.4 2.0 1.1e-05 25.4 1.1 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 AEO66619.1 - 0.00027 20.5 0.1 0.0004 19.9 0.1 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.6 AEO66619.1 - 0.056 12.7 0.9 0.099 11.9 0.6 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CoA_transf_3 PF02515.12 AEO66620.1 - 4.5e-58 195.6 0.0 8.2e-58 194.8 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III PHD PF00628.24 AEO66621.1 - 1.1e-08 34.6 7.3 1.8e-08 33.9 5.1 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 AEO66621.1 - 0.00056 19.2 3.0 0.0011 18.2 2.1 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Cut8_M PF14483.1 AEO66621.1 - 0.033 13.9 2.1 0.073 12.8 1.4 1.5 1 0 0 1 1 1 0 Cut8 dimerisation domain C1_1 PF00130.17 AEO66621.1 - 0.13 12.0 14.2 0.027 14.1 5.3 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 AEO66621.1 - 0.26 11.1 4.1 0.51 10.2 2.8 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger PHD_2 PF13831.1 AEO66621.1 - 2.1 7.7 10.2 0.69 9.2 3.3 2.6 2 1 0 2 2 2 0 PHD-finger Metal_resist PF13801.1 AEO66622.1 - 0.062 13.2 0.6 0.25 11.3 0.2 2.1 2 0 0 2 2 2 0 Heavy-metal resistance 3HCDH_N PF02737.13 AEO66623.1 - 1.6e-27 96.3 0.0 3.4e-27 95.2 0.0 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 AEO66623.1 - 7.8e-15 55.0 0.0 1.3e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.14 AEO66623.1 - 0.00029 20.0 0.0 0.00048 19.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 AEO66623.1 - 0.0045 16.7 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 AEO66623.1 - 0.0053 17.1 0.0 0.0093 16.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 AEO66623.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 AEO66623.1 - 0.042 14.1 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_2 PF03446.10 AEO66623.1 - 0.046 13.5 0.0 0.083 12.7 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 AEO66623.1 - 0.18 11.8 0.0 0.56 10.2 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 AEO66625.1 - 5.4e-07 29.8 0.2 9.3e-07 29.0 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 AEO66625.1 - 1.4e-05 24.4 0.0 3.2e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family ETF PF01012.16 AEO66625.1 - 0.004 16.8 2.3 0.0091 15.7 1.6 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein domain TIM PF00121.13 AEO66626.1 - 5e-50 169.8 0.0 5.7e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Rrf2 PF02082.15 AEO66626.1 - 0.092 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator LacAB_rpiB PF02502.13 AEO66627.1 - 7.3e-42 142.3 0.7 8.5e-42 142.1 0.5 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF3773 PF12608.3 AEO66627.1 - 0.0017 18.3 0.1 0.0041 17.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3773) Dak1 PF02733.12 AEO66628.1 - 1.5e-109 365.4 0.1 2.1e-109 365.0 0.1 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 AEO66628.1 - 4.6e-38 130.6 4.7 1e-37 129.4 3.2 1.6 1 0 0 1 1 1 1 DAK2 domain F_bP_aldolase PF01116.15 AEO66629.1 - 1.1e-84 283.9 0.1 1.2e-84 283.8 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II NAD_binding_11 PF14833.1 AEO66630.1 - 2.3e-37 127.7 4.4 6.7e-27 93.9 0.1 2.8 2 1 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 AEO66630.1 - 7.2e-33 113.7 0.0 1.4e-32 112.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AEO66630.1 - 9.7e-05 22.7 0.0 0.00029 21.1 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 AEO66630.1 - 0.00014 21.6 0.1 0.00043 19.9 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 AEO66630.1 - 0.0035 16.7 0.0 0.0065 15.9 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 AEO66630.1 - 0.3 10.8 1.7 4.3 7.0 0.1 2.9 2 1 1 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pre-SET PF05033.11 AEO66631.1 - 2.2e-22 79.2 7.6 5.9e-22 77.8 3.7 2.2 2 0 0 2 2 2 1 Pre-SET motif SET PF00856.23 AEO66631.1 - 1.6e-21 77.3 2.9 7.3e-21 75.1 0.0 3.0 2 2 1 3 3 3 1 SET domain Rad60-SLD_2 PF13881.1 AEO66632.1 - 0.00015 21.6 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AEO66632.1 - 0.0023 18.1 0.1 0.0053 16.9 0.1 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 AEO66632.1 - 0.0039 16.5 0.0 0.0072 15.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 AEO66632.1 - 0.028 14.0 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Adaptin_N PF01602.15 AEO66633.1 - 3e-94 316.2 2.2 4.8e-94 315.5 1.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 AEO66633.1 - 2.7e-62 208.2 0.0 8.1e-62 206.7 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 AEO66633.1 - 4.2e-62 207.9 0.6 8.3e-62 207.0 0.4 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 AEO66633.1 - 3.4e-10 40.0 8.6 1.5e-05 25.1 0.0 4.7 2 1 2 4 4 4 3 HEAT repeats Cnd1 PF12717.2 AEO66633.1 - 9.8e-06 25.5 3.8 0.00097 19.0 0.0 3.8 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 AEO66633.1 - 0.00059 19.7 0.1 0.84 9.8 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 AEO66633.1 - 0.038 14.4 1.6 4.6 7.8 0.0 3.8 3 0 0 3 3 3 0 HEAT-like repeat RE_Alw26IDE PF09665.5 AEO66633.1 - 0.1 11.2 2.0 1.5 7.4 0.1 3.0 2 1 1 3 3 3 0 Type II restriction endonuclease (RE_Alw26IDE) Mago_nashi PF02792.9 AEO66634.1 - 5.4e-76 253.1 0.3 6.3e-76 252.8 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein FlbT PF07378.6 AEO66634.1 - 0.087 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Flagellar protein FlbT Vac_ImportDeg PF09783.4 AEO66635.1 - 2e-70 235.8 2.3 2.7e-70 235.4 1.6 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein UPF0020 PF01170.13 AEO66636.1 - 2e-09 37.2 0.1 6.9e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 AEO66636.1 - 3.3e-06 27.1 0.0 7.6e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TylF PF05711.6 AEO66636.1 - 0.18 10.8 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Ribonuc_P_40 PF08584.6 AEO66637.1 - 1.2e-23 83.5 0.0 1.6e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Ank_5 PF13857.1 AEO66638.1 - 5.1e-13 48.8 0.4 1.7e-09 37.5 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO66638.1 - 1.4e-07 31.8 0.0 6.3e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 AEO66638.1 - 0.00052 19.6 0.0 0.0024 17.6 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 AEO66638.1 - 0.00053 19.9 0.1 0.0044 17.1 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 AEO66638.1 - 0.00067 19.9 0.1 0.0012 19.1 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Glyco_trans_1_2 PF13524.1 AEO66638.1 - 0.058 13.6 1.0 2.1 8.6 0.1 2.6 3 0 0 3 3 3 0 Glycosyl transferases group 1 DnaB_bind PF10410.4 AEO66638.1 - 0.45 10.5 0.2 0.45 10.5 0.1 2.3 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase Amidohydro_4 PF13147.1 AEO66640.1 - 1.3e-30 107.4 7.4 4.2e-15 56.5 0.9 2.1 1 1 1 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 AEO66640.1 - 1.2e-14 54.7 0.9 2.2e-14 53.8 0.6 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 AEO66640.1 - 6.5e-09 35.4 12.1 4.8e-07 29.3 5.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 AEO66640.1 - 2.7e-08 33.4 0.5 2.7e-08 33.4 0.3 1.9 2 0 0 2 2 2 1 Amidohydrolase tRNA_lig_CPD PF08302.6 AEO66641.1 - 2.9e-84 282.2 0.0 4e-84 281.8 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.5 AEO66641.1 - 8.2e-80 267.4 0.0 1.4e-79 266.7 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 AEO66641.1 - 1e-56 191.3 0.1 3.6e-56 189.6 0.0 1.9 2 0 0 2 2 2 1 tRNA ligase kinase domain Glycos_transf_3 PF00591.16 AEO66642.1 - 1.3e-58 198.3 0.0 2.8e-38 131.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 AEO66642.1 - 7.4e-10 38.2 0.0 2.2e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Lip_A_acyltrans PF03279.8 AEO66642.1 - 0.19 10.6 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase Ribosomal_L10 PF00466.15 AEO66643.1 - 0.0015 18.4 0.0 0.014 15.3 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L10 Phage-tail_3 PF13550.1 AEO66643.1 - 0.059 13.1 0.2 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Putative phage tail protein Tic20 PF09685.5 AEO66644.1 - 2.4e-07 30.7 1.4 3.3e-07 30.2 1.0 1.1 1 0 0 1 1 1 1 Tic20-like protein DUF3782 PF12644.2 AEO66644.1 - 0.038 13.7 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) AAA PF00004.24 AEO66645.1 - 1.7e-40 138.3 0.0 4.9e-40 136.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AEO66645.1 - 4.1e-05 23.3 0.4 0.00021 21.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AEO66645.1 - 9.6e-05 22.4 0.4 0.0077 16.2 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 AEO66645.1 - 0.00025 20.1 0.0 0.00062 18.8 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 AEO66645.1 - 0.00092 19.1 0.4 0.0084 16.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AEO66645.1 - 0.0055 16.8 4.6 0.019 15.0 0.0 3.0 3 1 1 4 4 3 1 AAA domain PhoH PF02562.11 AEO66645.1 - 0.0058 15.8 0.3 0.042 13.0 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 AEO66645.1 - 0.0083 15.3 0.1 0.026 13.7 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 AEO66645.1 - 0.0099 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 AEO66645.1 - 0.015 14.1 0.0 0.033 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 AEO66645.1 - 0.018 14.8 0.4 0.044 13.5 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 AEO66645.1 - 0.022 14.1 0.1 0.046 13.1 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 AEO66645.1 - 0.031 13.6 1.4 0.32 10.3 0.2 2.5 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 AEO66645.1 - 0.045 13.3 0.1 0.14 11.7 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AEO66645.1 - 0.095 13.5 0.1 0.095 13.5 0.1 2.9 2 2 0 2 2 2 0 AAA domain AAA_11 PF13086.1 AEO66645.1 - 0.38 10.2 3.6 0.61 9.6 0.0 2.5 2 2 0 2 2 2 0 AAA domain Clr5 PF14420.1 AEO66646.1 - 1.7e-23 82.2 3.2 3e-23 81.4 2.2 1.4 1 0 0 1 1 1 1 Clr5 domain Ish1 PF10281.4 AEO66647.1 - 8.9e-86 281.4 10.2 6.2e-13 48.5 0.0 8.4 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.22 AEO66647.1 - 3.4e-11 42.3 0.0 0.068 12.6 0.0 7.2 10 0 0 10 10 10 2 SAP domain Slx4 PF09494.5 AEO66647.1 - 1.4e-07 31.1 3.4 0.52 10.0 0.0 6.9 7 0 0 7 7 7 1 Slx4 endonuclease APC2 PF08672.6 AEO66647.1 - 1.6e-05 25.0 0.8 16 5.8 0.0 6.5 8 0 0 8 8 8 1 Anaphase promoting complex (APC) subunit 2 HeH PF12949.2 AEO66647.1 - 2.5e-05 23.7 0.0 6 6.5 0.0 5.6 6 0 0 6 6 6 1 HeH/LEM domain LEM PF03020.10 AEO66647.1 - 0.014 14.8 0.0 2.8 7.4 0.0 4.1 4 0 0 4 4 4 0 LEM domain TrbL PF04610.9 AEO66647.1 - 0.66 9.6 4.5 16 5.1 1.9 2.3 1 1 1 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein Tape_meas_lam_C PF09718.5 AEO66647.1 - 0.82 9.6 18.9 2.2 8.2 1.9 3.7 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF2795 PF11387.3 AEO66647.1 - 1.2 9.0 3.6 55 3.7 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF2795) SPOR PF05036.8 AEO66648.1 - 0.078 13.1 0.3 4.3 7.5 0.1 2.2 2 0 0 2 2 2 0 Sporulation related domain MFS_1 PF07690.11 AEO66649.1 - 2.2e-47 161.4 44.5 1.4e-44 152.2 30.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M56 PF05569.6 AEO66649.1 - 0.29 10.0 1.6 0.5 9.2 1.1 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF2207 PF09972.4 AEO66649.1 - 1.5 7.2 4.6 0.94 7.9 0.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.1 AEO66649.1 - 4.3 6.7 29.8 0.022 14.1 1.4 4.6 3 1 2 5 5 5 0 Domain of unknown function (DUF4131) HCBP_related PF06594.6 AEO66650.1 - 0.07 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain Serglycin PF04360.7 AEO66651.1 - 0.04 13.6 0.7 0.073 12.7 0.5 1.4 1 0 0 1 1 1 0 Serglycin Annexin PF00191.15 AEO66652.1 - 1.1e-65 217.4 4.6 3.5e-19 68.4 0.0 4.5 4 1 0 4 4 4 4 Annexin zf-C2H2 PF00096.21 AEO66653.1 - 2.6 8.5 11.6 0.29 11.5 1.6 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO66653.1 - 7.2 7.1 13.4 0.074 13.4 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger OPA3 PF07047.7 AEO66654.1 - 1.2 8.9 4.1 2.2 8.0 2.8 1.4 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) CHIPS PF11434.3 AEO66655.1 - 0.18 11.4 2.3 0.21 11.2 1.6 1.1 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS Git3 PF11710.3 AEO66657.1 - 2.3e-19 69.7 5.3 5e-19 68.6 3.7 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 AEO66657.1 - 2.4e-09 36.7 4.0 2.4e-09 36.7 2.8 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 AEO66657.1 - 0.0033 16.3 6.1 0.0053 15.6 4.2 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor DUF4381 PF14316.1 AEO66657.1 - 0.018 15.1 0.8 1.8 8.6 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF1180 PF06679.7 AEO66657.1 - 0.68 9.7 0.0 0.68 9.7 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) CDO_I PF05995.7 AEO66658.1 - 1.5e-40 138.2 0.0 1.9e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 AEO66658.1 - 0.01 15.2 0.2 0.016 14.5 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) Voltage_CLC PF00654.15 AEO66659.1 - 8e-89 298.1 29.9 8e-89 298.1 20.7 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 AEO66659.1 - 5.6e-14 51.6 0.5 4.5e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.18 AEO66660.1 - 2.6e-11 43.4 0.2 4.4e-11 42.6 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AEO66660.1 - 0.032 14.3 0.1 0.047 13.8 0.1 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 LRR_9 PF14580.1 AEO66661.1 - 4.1e-49 166.5 0.2 8.9e-49 165.3 0.0 1.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 AEO66661.1 - 1.9e-11 43.3 9.0 2.6e-07 30.1 0.4 4.4 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO66661.1 - 4.5e-08 32.7 4.1 2.2e-07 30.5 0.1 3.4 4 1 0 4 4 4 1 Leucine rich repeat LRR_7 PF13504.1 AEO66661.1 - 0.003 17.4 4.5 1.6 9.2 0.2 4.6 4 0 0 4 4 4 1 Leucine rich repeat DUF4349 PF14257.1 AEO66661.1 - 0.018 14.3 1.9 0.029 13.5 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) LRR_1 PF00560.28 AEO66661.1 - 0.071 13.1 6.4 95 3.6 0.0 5.6 5 1 0 5 5 5 0 Leucine Rich Repeat PspB PF06667.7 AEO66661.1 - 0.59 10.1 3.2 0.85 9.5 1.0 2.1 2 0 0 2 2 2 0 Phage shock protein B LRR_6 PF13516.1 AEO66661.1 - 1 9.6 5.2 14 6.0 0.3 4.1 5 0 0 5 5 5 0 Leucine Rich repeat Pkinase PF00069.20 AEO66662.1 - 5.5e-26 91.2 0.0 9.4e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 AEO66662.1 - 3.1e-16 58.5 6.9 5.2e-10 38.8 0.1 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.17 AEO66662.1 - 4.1e-10 38.8 9.9 0.059 13.4 0.3 6.5 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 AEO66662.1 - 4e-07 30.3 3.2 0.0019 18.6 0.5 4.7 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.1 AEO66662.1 - 4.2e-07 30.1 2.7 0.027 14.7 0.2 4.4 1 1 2 3 3 3 3 HEAT repeats Pkinase_Tyr PF07714.12 AEO66662.1 - 3.8e-05 22.9 0.0 5.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_9 PF14604.1 AEO66663.1 - 9.7e-07 28.2 0.2 2.1e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AEO66663.1 - 0.0023 17.2 0.3 0.0047 16.2 0.2 1.5 1 0 0 1 1 1 1 SH3 domain Metallophos PF00149.23 AEO66664.1 - 3e-44 150.8 1.0 3.8e-44 150.4 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Vps51 PF08700.6 AEO66665.1 - 2.2e-17 62.6 3.2 2.2e-17 62.6 2.2 3.0 3 1 0 3 3 3 1 Vps51/Vps67 COG2 PF06148.6 AEO66665.1 - 0.00014 21.7 3.5 0.0069 16.2 0.0 2.8 2 1 1 3 3 3 2 COG (conserved oligomeric Golgi) complex component, COG2 DUF2383 PF09537.5 AEO66665.1 - 0.0029 17.8 5.0 0.024 14.8 0.6 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2383) Laminin_B PF00052.13 AEO66665.1 - 0.013 15.0 2.9 0.036 13.6 0.7 2.5 2 1 0 2 2 2 0 Laminin B (Domain IV) Sec5 PF15469.1 AEO66665.1 - 0.025 14.2 7.1 0.86 9.3 0.1 2.7 3 0 0 3 3 3 0 Exocyst complex component Sec5 DASH_Dam1 PF08653.5 AEO66665.1 - 0.058 13.1 0.4 6.8 6.5 0.0 3.0 2 1 1 3 3 3 0 DASH complex subunit Dam1 V_ATPase_I PF01496.14 AEO66665.1 - 2.6 5.8 12.6 0.34 8.6 0.5 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family MAS20 PF02064.10 AEO66666.1 - 1.3e-18 67.0 1.1 3e-18 65.8 0.8 1.5 1 1 0 1 1 1 1 MAS20 protein import receptor RskA PF10099.4 AEO66666.1 - 0.037 13.7 0.8 0.046 13.4 0.5 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3365 PF11845.3 AEO66666.1 - 0.09 12.6 0.6 0.12 12.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) DUF4381 PF14316.1 AEO66666.1 - 0.094 12.8 0.1 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Trp_oprn_chp PF09534.5 AEO66666.1 - 0.48 10.0 3.1 0.65 9.5 2.1 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3987 PF13148.1 AEO66666.1 - 1.9 6.9 5.7 2.5 6.5 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Wyosine_form PF08608.7 AEO66667.1 - 6.9e-24 83.7 0.0 1.7e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 AEO66667.1 - 9.4e-23 81.1 0.1 2e-22 80.1 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.20 AEO66667.1 - 2.4e-09 37.3 0.0 3.5e-08 33.5 0.0 2.5 1 1 0 1 1 1 1 Flavodoxin EmrE PF13536.1 AEO66668.1 - 8.8e-05 22.6 6.0 8.8e-05 22.6 4.2 2.0 1 1 1 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 AEO66668.1 - 0.0011 18.9 10.8 0.0028 17.6 7.5 1.7 1 1 1 2 2 2 1 EamA-like transporter family UPF0546 PF10639.4 AEO66668.1 - 0.012 15.4 3.4 0.018 14.8 2.3 1.4 1 1 0 1 1 1 0 Uncharacterised protein family UPF0546 Tox-MPTase5 PF15641.1 AEO66668.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Metallopeptidase toxin 5 TPT PF03151.11 AEO66668.1 - 1.6 8.3 7.6 3.1 7.4 4.7 1.8 1 1 1 2 2 2 0 Triose-phosphate Transporter family TFIIA_gamma_C PF02751.9 AEO66669.1 - 5.1e-26 90.2 1.3 7e-26 89.7 0.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 AEO66669.1 - 2.8e-24 84.4 0.2 3.9e-24 83.9 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain ATP-synt_C PF00137.16 AEO66670.1 - 9.7e-27 92.6 30.0 1.3e-16 60.2 5.9 2.9 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.19 AEO66670.1 - 4.8 6.8 7.3 6.3 6.4 3.2 2.4 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MoCF_biosynth PF00994.19 AEO66671.1 - 2.6e-56 189.0 1.6 3.3e-31 107.6 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 AEO66671.1 - 8.3e-32 109.7 5.9 1.5e-31 108.9 4.1 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 AEO66671.1 - 8.1e-16 57.7 0.0 4.3e-15 55.4 0.0 2.3 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) Zip PF02535.17 AEO66671.1 - 0.014 14.4 4.0 0.02 13.8 2.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Innate_immun PF12782.2 AEO66671.1 - 1.6 7.8 17.5 2.7 7.1 12.1 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family SelP_N PF04592.9 AEO66671.1 - 3.5 6.9 17.4 5.4 6.3 12.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region BAF1_ABF1 PF04684.8 AEO66671.1 - 3.5 6.3 16.8 5.3 5.7 11.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RNase_P_Rpp14 PF01900.14 AEO66673.1 - 2.3e-09 37.0 0.0 2.9e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.12 AEO66674.1 - 5.1e-66 222.6 0.0 6.7e-66 222.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein WD40 PF00400.27 AEO66675.1 - 1.1e-21 75.7 2.4 5.8e-05 22.8 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat WD40 PF00400.27 AEO66677.1 - 2.1e-38 128.8 9.2 7e-10 38.4 0.2 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 AEO66677.1 - 1.4e-05 23.4 11.4 0.04 12.0 0.4 4.6 2 2 3 5 5 5 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 AEO66677.1 - 0.041 13.3 0.7 0.39 10.1 0.0 2.5 2 1 0 3 3 3 0 PQQ-like domain IncA PF04156.9 AEO66677.1 - 0.093 12.3 3.1 0.12 11.9 1.4 1.7 2 0 0 2 2 2 0 IncA protein APG6 PF04111.7 AEO66677.1 - 0.095 11.7 5.4 0.15 11.0 3.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS-augmin3 PF14932.1 AEO66677.1 - 1.6 7.8 5.3 3 6.9 3.7 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Seryl_tRNA_N PF02403.17 AEO66677.1 - 5.7 7.0 8.7 23 5.0 4.0 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CM_2 PF01817.16 AEO66678.1 - 3.5e-07 30.2 0.0 0.00021 21.2 0.0 2.9 2 1 0 2 2 2 2 Chorismate mutase type II BCIP PF13862.1 AEO66679.1 - 9.3e-66 221.0 0.1 1.2e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein UPF0184 PF03670.8 AEO66679.1 - 0.24 11.5 2.4 0.8 9.9 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) COPI_assoc PF08507.5 AEO66680.1 - 2.2e-46 156.9 6.0 2.5e-46 156.8 4.2 1.0 1 0 0 1 1 1 1 COPI associated protein ExoD PF06055.7 AEO66680.1 - 0.012 14.7 5.1 0.038 13.1 0.9 2.1 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD UCR_Fe-S_N PF10399.4 AEO66680.1 - 0.085 12.0 0.1 0.17 11.0 0.1 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal GATA PF00320.22 AEO66681.1 - 4.1e-32 109.2 16.4 6.9e-17 60.5 2.1 2.7 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 AEO66681.1 - 2.1e-07 30.1 2.4 0.0011 18.1 0.0 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 AEO66681.1 - 0.00035 20.1 0.3 0.00035 20.1 0.2 2.9 3 0 0 3 3 3 2 Putative transposase DNA-binding domain RRN7 PF11781.3 AEO66681.1 - 0.00051 19.4 7.6 0.018 14.5 0.4 2.5 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 AEO66681.1 - 0.001 18.9 2.2 0.79 9.7 0.1 2.8 2 0 0 2 2 2 2 Zinc ribbon domain zf-ribbon_3 PF13248.1 AEO66681.1 - 0.0013 17.9 6.3 0.28 10.4 0.2 2.8 2 1 0 2 2 2 2 zinc-ribbon domain Auto_anti-p27 PF06677.7 AEO66681.1 - 0.017 14.8 3.8 0.45 10.3 0.2 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ArfGap PF01412.13 AEO66681.1 - 0.024 14.4 2.9 3.8 7.3 0.2 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DZR PF12773.2 AEO66681.1 - 0.16 11.8 15.7 22 4.9 4.9 3.2 1 1 1 2 2 2 0 Double zinc ribbon Elf1 PF05129.8 AEO66681.1 - 0.97 9.1 3.0 22 4.8 0.6 2.9 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like eIF-5_eIF-2B PF01873.12 AEO66681.1 - 1.6 8.3 10.1 3.8 7.1 0.4 3.1 3 0 0 3 3 3 0 Domain found in IF2B/IF5 HypA PF01155.14 AEO66681.1 - 1.6 8.4 7.0 0.64 9.7 0.1 2.7 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1595 PF12760.2 AEO66681.1 - 2.6 7.9 6.4 7 6.5 0.7 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_3 PF13878.1 AEO66681.1 - 6.3 6.4 10.9 6.8 6.3 0.3 4.1 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO zf-Sec23_Sec24 PF04810.10 AEO66681.1 - 9.9 5.8 14.4 0.12 11.9 0.3 3.0 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger AAA-ATPase_like PF09820.4 AEO66682.1 - 0.19 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Predicted AAA-ATPase SAP PF02037.22 AEO66683.1 - 2.1e-14 52.5 0.1 4.2e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 SAP domain RRM_1 PF00076.17 AEO66683.1 - 0.11 12.1 0.0 0.36 10.4 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HeH PF12949.2 AEO66683.1 - 0.16 11.5 0.2 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 HeH/LEM domain RRM_5 PF13893.1 AEO66683.1 - 0.24 11.2 0.0 0.46 10.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GATase PF00117.23 AEO66684.1 - 1.1e-46 158.7 0.0 1.5e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 AEO66684.1 - 1.4e-46 157.2 0.0 2.1e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 AEO66684.1 - 1.9e-06 27.4 0.2 0.0015 18.0 0.1 2.7 1 1 1 2 2 2 2 Peptidase C26 ETF PF01012.16 AEO66685.1 - 7.9e-38 129.7 0.4 9.5e-38 129.4 0.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ArfGap PF01412.13 AEO66686.1 - 3.4e-32 110.6 0.1 5.9e-32 109.8 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TarH PF02203.10 AEO66686.1 - 0.064 13.0 1.2 0.11 12.3 0.9 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue RRM_1 PF00076.17 AEO66687.1 - 5.4e-30 102.8 0.0 1.7e-14 53.1 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO66687.1 - 1.2e-23 82.8 0.0 3.9e-12 45.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO66687.1 - 1e-08 34.8 0.0 0.0026 17.5 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 AEO66687.1 - 0.0015 17.0 4.5 0.0025 16.3 3.1 1.2 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) DbpA PF03880.10 AEO66687.1 - 0.034 13.8 0.2 3.8 7.2 0.0 2.6 3 0 0 3 3 3 0 DbpA RNA binding domain SPDY PF03771.11 AEO66687.1 - 1.9 8.0 7.1 0.13 11.7 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF317) RVT_1 PF00078.22 AEO66688.1 - 3.5e-05 23.2 0.4 4.8e-05 22.8 0.3 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Plasmod_dom_1 PF09715.5 AEO66688.1 - 1.2 9.1 5.5 0.25 11.3 0.4 2.3 1 1 1 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) Flavodoxin_1 PF00258.20 AEO66689.1 - 7.7e-27 94.0 0.0 1.2e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 AEO66689.1 - 4.1e-21 75.4 0.0 6.4e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 AEO66689.1 - 3.5e-11 43.6 0.0 2.6e-08 34.3 0.0 2.7 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 AEO66689.1 - 0.0072 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_5 PF12724.2 AEO66689.1 - 0.045 13.7 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin domain Asp PF00026.18 AEO66690.1 - 9e-11 41.5 0.3 2.5e-10 40.1 0.2 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease CCSMST1 PF15013.1 AEO66690.1 - 0.11 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 CCSMST1 family F-box-like PF12937.2 AEO66693.1 - 3e-09 36.4 0.1 5.2e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO66693.1 - 2.7e-06 26.8 0.0 5.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 F-box domain UIM PF02809.15 AEO66693.1 - 0.00034 19.9 16.8 0.01 15.3 2.1 3.9 3 0 0 3 3 3 2 Ubiquitin interaction motif Siva PF05458.7 AEO66695.1 - 0.62 9.6 18.8 0.27 10.8 2.3 3.1 3 0 0 3 3 3 0 Cd27 binding protein (Siva) FYVE_2 PF02318.11 AEO66695.1 - 1.1 9.1 24.2 3.1 7.7 0.2 3.6 4 0 0 4 4 4 0 FYVE-type zinc finger DUF3279 PF11682.3 AEO66695.1 - 3.8 7.1 18.2 0.44 10.1 1.3 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3279) Clr2 PF10383.4 AEO66696.1 - 2.7e-23 82.4 0.0 1.2e-22 80.3 0.0 2.0 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 Pex14_N PF04695.8 AEO66696.1 - 0.057 13.4 4.2 0.1 12.6 2.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 AEO66696.1 - 3.3 7.3 6.3 4.9 6.7 4.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 AEO66696.1 - 4.7 5.3 19.1 8.6 4.4 13.1 1.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 AIG2 PF06094.7 AEO66698.1 - 1.1e-05 25.8 0.0 1.9e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family Nop14 PF04147.7 AEO66699.1 - 0.17 9.7 12.7 0.28 9.0 8.8 1.3 1 0 0 1 1 1 0 Nop14-like family PBP_sp32 PF07222.7 AEO66699.1 - 0.18 10.9 4.7 0.32 10.1 3.3 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pox_Ag35 PF03286.9 AEO66699.1 - 0.7 9.3 18.8 0.022 14.2 6.3 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CDC27 PF09507.5 AEO66699.1 - 0.83 8.8 23.3 0.13 11.4 6.3 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 PBP1_TM PF14812.1 AEO66699.1 - 3.5 8.0 27.3 0.32 11.3 3.7 3.0 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PGA2 PF07543.7 AEO66699.1 - 5.2 6.8 15.4 2.4 7.9 8.5 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 SUN PF03856.8 AEO66700.1 - 1.1e-76 257.4 8.7 1.5e-76 256.9 6.0 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) TPR_12 PF13424.1 AEO66701.1 - 0.069 13.0 1.9 1.3 9.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 AEO66701.1 - 0.1 12.5 1.0 0.57 10.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Thiolase_N PF00108.18 AEO66702.1 - 1.8e-92 309.0 0.3 2.8e-92 308.4 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AEO66702.1 - 1.7e-38 130.8 0.8 4.3e-38 129.5 0.6 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 AEO66702.1 - 0.00027 20.4 2.1 0.00041 19.9 0.3 2.1 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain UQ_con PF00179.21 AEO66703.1 - 7.6e-52 174.4 0.0 8.6e-52 174.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO66703.1 - 8.5e-07 28.7 0.0 9.8e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AEO66703.1 - 0.026 14.3 0.2 0.054 13.4 0.1 1.6 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.18 AEO66704.1 - 2.4e-113 378.2 0.7 5.3e-113 377.1 0.5 1.6 1 0 0 1 1 1 1 Kinesin motor domain adh_short PF00106.20 AEO66706.1 - 1.8e-13 50.7 0.0 1.9e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO66706.1 - 0.0025 17.6 0.0 0.0029 17.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO66706.1 - 0.14 11.7 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 KR domain LCM PF04072.9 AEO66707.1 - 1.1e-25 90.2 0.0 1e-24 87.1 0.0 2.0 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase TFIID-18kDa PF02269.11 AEO66709.1 - 3.8e-25 87.5 0.5 6.8e-24 83.4 0.0 2.6 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Myc_N PF01056.13 AEO66709.1 - 0.046 12.8 0.6 0.067 12.3 0.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region LigT_PEase PF02834.11 AEO66709.1 - 0.055 13.4 0.2 0.96 9.4 0.0 2.8 3 0 0 3 3 3 0 LigT like Phosphoesterase Ist1 PF03398.9 AEO66710.1 - 1.9e-64 216.0 1.9 2.4e-64 215.6 1.3 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway zf-CCHC_2 PF13696.1 AEO66711.1 - 0.0037 16.7 1.2 0.0037 16.7 0.9 2.5 1 1 1 2 2 2 1 Zinc knuckle eIF3g PF12353.3 AEO66711.1 - 0.045 13.6 0.3 0.045 13.6 0.2 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Clat_adaptor_s PF01217.15 AEO66712.1 - 4.2e-57 191.8 2.0 4.6e-57 191.7 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MFS_1 PF07690.11 AEO66713.1 - 4.1e-20 71.7 22.4 6e-20 71.2 14.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 AEO66713.1 - 6.5e-11 41.9 3.4 6.5e-11 41.9 2.4 1.8 2 0 0 2 2 2 1 Nodulin-like Serinc PF03348.10 AEO66714.1 - 1.9e-177 590.3 4.4 2.3e-177 590.0 3.0 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Cys_Met_Meta_PP PF01053.15 AEO66715.1 - 1.2e-139 464.9 0.0 1.4e-139 464.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 AEO66715.1 - 8.2e-07 28.0 0.0 1.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 AEO66715.1 - 2.6e-06 26.6 0.0 4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 AEO66715.1 - 2.2e-05 23.6 0.1 0.00011 21.3 0.1 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.6 AEO66715.1 - 0.00011 20.6 0.1 0.0003 19.1 0.0 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 AEO66715.1 - 0.0002 20.2 0.1 0.00038 19.2 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 AEO66715.1 - 0.002 17.3 0.1 0.0048 16.0 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase AAA PF00004.24 AEO66716.1 - 4.5e-38 130.4 0.0 7.4e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AEO66716.1 - 8.6e-07 29.1 0.1 4.1e-05 23.6 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 AEO66716.1 - 1.1e-05 25.5 0.1 0.0019 18.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 AEO66716.1 - 1.4e-05 24.2 0.0 2.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 AEO66716.1 - 1.6e-05 24.6 0.1 0.00019 21.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AEO66716.1 - 1.8e-05 24.6 0.0 3.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO66716.1 - 3.6e-05 24.5 0.1 0.00016 22.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 AEO66716.1 - 8.4e-05 22.5 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 AEO66716.1 - 0.00067 19.1 3.1 0.11 11.9 0.1 3.7 3 2 1 4 4 4 1 AAA domain AAA_33 PF13671.1 AEO66716.1 - 0.00087 19.1 0.0 0.0023 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AEO66716.1 - 0.00095 18.6 0.2 0.0023 17.3 0.1 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 AEO66716.1 - 0.0012 18.5 0.7 0.0066 16.1 0.2 2.3 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 AEO66716.1 - 0.0014 17.8 0.1 0.0026 16.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 AEO66716.1 - 0.003 17.6 0.0 0.0077 16.2 0.0 1.7 2 0 0 2 2 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 AEO66716.1 - 0.006 15.6 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 AEO66716.1 - 0.0078 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 AEO66716.1 - 0.0081 16.3 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.8 AEO66716.1 - 0.0095 14.8 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 AEO66716.1 - 0.016 14.7 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AEO66716.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 AEO66716.1 - 0.024 14.1 0.0 0.054 12.9 0.0 1.5 2 0 0 2 2 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 AEO66716.1 - 0.028 13.2 0.0 0.059 12.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 AEO66716.1 - 0.034 13.8 0.0 0.17 11.5 0.0 1.9 1 1 1 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 AEO66716.1 - 0.037 14.3 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 AEO66716.1 - 0.067 12.6 0.0 0.33 10.3 0.0 2.1 2 1 0 2 2 2 0 Guanylate kinase TIP49 PF06068.8 AEO66716.1 - 0.069 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Parvo_NS1 PF01057.12 AEO66716.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 AEO66716.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein Csm1 PF12539.3 AEO66717.1 - 3.9e-26 91.3 0.0 1e-25 90.0 0.0 1.7 2 0 0 2 2 1 1 Chromosome segregation protein Csm1/Pcs1 Cast PF10174.4 AEO66717.1 - 0.0039 15.3 8.4 0.0056 14.8 5.8 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone AAA_13 PF13166.1 AEO66717.1 - 0.004 15.7 4.2 0.0055 15.2 2.9 1.1 1 0 0 1 1 1 1 AAA domain Laps PF10169.4 AEO66717.1 - 0.014 15.6 2.7 0.014 15.6 1.9 2.0 2 0 0 2 2 1 0 Learning-associated protein ADIP PF11559.3 AEO66717.1 - 0.02 14.8 8.9 0.038 13.8 6.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.7 AEO66717.1 - 0.061 13.5 1.3 0.14 12.3 0.9 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Fmp27_WPPW PF10359.4 AEO66717.1 - 0.091 11.1 2.4 0.14 10.5 1.7 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spc7 PF08317.6 AEO66717.1 - 0.091 11.4 9.9 0.13 10.8 6.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Bap31 PF05529.7 AEO66717.1 - 0.1 12.0 5.6 0.21 11.0 3.9 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Matrilin_ccoil PF10393.4 AEO66717.1 - 0.11 11.8 9.2 1.4 8.3 2.1 3.4 2 1 2 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF1664 PF07889.7 AEO66717.1 - 0.12 12.1 1.9 0.24 11.2 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.10 AEO66717.1 - 0.14 11.6 3.4 0.41 10.1 2.3 1.9 1 0 0 1 1 1 0 Septum formation initiator Atg14 PF10186.4 AEO66717.1 - 0.16 10.9 7.1 0.24 10.3 5.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 AEO66717.1 - 0.23 11.4 7.4 0.56 10.2 5.2 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 AEO66717.1 - 0.28 10.7 13.5 1.1 8.7 9.4 1.9 1 1 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 AEO66717.1 - 0.35 8.6 1.3 0.46 8.2 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 AEO66717.1 - 0.4 9.6 10.1 0.64 9.0 7.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3373 PF11853.3 AEO66717.1 - 0.94 7.9 3.1 1.3 7.5 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Fib_alpha PF08702.5 AEO66717.1 - 1.1 9.3 5.5 3.6 7.7 3.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FliD_N PF02465.13 AEO66717.1 - 2.6 8.4 12.5 7.8 6.9 8.4 2.1 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Val_tRNA-synt_C PF10458.4 AEO66717.1 - 5.4 7.1 12.7 0.47 10.5 1.3 2.8 2 1 1 3 3 2 0 Valyl tRNA synthetase tRNA binding arm PGAP1 PF07819.8 AEO66718.1 - 1.3e-88 296.3 0.0 1.8e-88 295.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 AEO66718.1 - 9.8e-07 28.6 0.1 2.2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO66718.1 - 7.6e-06 25.9 0.8 1.9e-05 24.6 0.6 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO66718.1 - 0.0071 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 AEO66718.1 - 0.066 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF676 PF05057.9 AEO66718.1 - 0.067 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) MutL_C PF08676.6 AEO66719.1 - 9.8e-23 80.3 0.1 2.9e-22 78.8 0.1 1.8 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 AEO66719.1 - 1.4e-17 63.2 0.0 3.6e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 AEO66719.1 - 5.4e-13 48.7 0.0 3.9e-12 46.0 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AEO66719.1 - 2e-11 43.6 0.0 5.1e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyr_redox_3 PF13738.1 AEO66721.1 - 3.1e-05 24.1 0.0 0.0012 18.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO66721.1 - 6.7e-05 22.8 0.0 0.00043 20.2 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO66721.1 - 0.0054 16.7 0.0 0.018 15.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 AEO66721.1 - 0.05 12.0 0.0 0.11 10.9 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein ETF PF01012.16 AEO66722.1 - 5e-41 140.1 1.3 5.2e-41 140.0 0.2 1.5 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 AEO66722.1 - 2e-36 123.4 0.3 5e-36 122.1 0.2 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain SWIRM PF04433.12 AEO66723.1 - 1.5e-35 121.1 0.1 2.8e-35 120.2 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 AEO66723.1 - 8.5e-08 32.1 0.0 1.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO66723.1 - 4.1e-05 23.5 0.5 8.5e-05 22.5 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 AEO66723.1 - 0.02 14.4 3.3 0.04 13.4 2.3 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type DUF1019 PF06254.6 AEO66723.1 - 0.3 11.2 2.1 0.59 10.3 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1019) Carn_acyltransf PF00755.15 AEO66725.1 - 2.5e-177 590.5 0.0 2.8e-177 590.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CAP_N PF01213.14 AEO66726.1 - 2.8e-87 292.9 12.1 2.8e-87 292.9 8.4 1.4 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 AEO66726.1 - 7.8e-52 174.8 3.2 1.1e-51 174.3 2.2 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 AEO66726.1 - 0.17 11.2 0.7 0.34 10.3 0.3 1.6 2 0 0 2 2 2 0 Tubulin binding cofactor C PfkB PF00294.19 AEO66727.1 - 1.4e-11 44.0 0.4 2.8e-10 39.8 0.2 2.0 2 0 0 2 2 2 2 pfkB family carbohydrate kinase MCM PF00493.18 AEO66728.1 - 8.7e-131 435.6 0.4 1.5e-130 434.8 0.2 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AEO66728.1 - 8.1e-18 65.0 0.1 7.2e-17 62.0 0.0 2.4 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 AEO66728.1 - 2.7e-07 29.9 0.0 3.3e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AEO66728.1 - 0.0028 17.2 0.0 0.0074 15.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AEO66728.1 - 0.0089 15.5 0.0 0.026 14.0 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain TFIIF_alpha PF05793.7 AEO66728.1 - 0.39 9.0 17.9 0.68 8.2 12.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3801 PF12687.2 AEO66728.1 - 2.6 7.5 9.7 6.4 6.2 1.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3801) Aminotran_3 PF00202.16 AEO66730.1 - 4.6e-84 282.1 0.0 5.5e-84 281.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Exo70 PF03081.10 AEO66731.1 - 8.9e-72 241.9 0.0 1.5e-71 241.2 0.0 1.4 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Syntaxin PF00804.20 AEO66731.1 - 0.095 12.8 8.2 1.7 8.8 0.1 3.4 3 0 0 3 3 3 0 Syntaxin Apolipoprotein PF01442.13 AEO66731.1 - 0.3 10.5 0.1 0.3 10.5 0.0 2.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 AEO66731.1 - 0.34 10.7 3.0 40 4.0 0.1 3.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.4 AEO66731.1 - 8.6 6.2 10.3 8 6.3 0.4 3.3 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FtsK_SpoIIIE PF01580.13 AEO66733.1 - 0.019 14.4 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family DXP_reductoisom PF02670.11 AEO66733.1 - 0.066 13.7 0.2 0.11 13.0 0.1 1.4 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase FAA_hydrolase PF01557.13 AEO66734.1 - 2.8e-50 170.7 0.0 3.9e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF1237 PF06824.6 AEO66735.1 - 2.1e-179 596.6 0.0 2.4e-179 596.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) CDC27 PF09507.5 AEO66736.1 - 1.2e-102 344.4 20.9 1.3e-102 344.2 14.5 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 PigN PF04987.9 AEO66737.1 - 2.9e-167 556.7 24.3 4.6e-167 556.1 16.8 1.3 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 AEO66737.1 - 9.9e-10 38.2 0.7 4.5e-08 32.8 0.5 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 AEO66737.1 - 2e-09 37.1 0.0 3.3e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 AEO66737.1 - 0.0012 18.3 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Fungal_trans PF04082.13 AEO66738.1 - 3.5e-36 124.4 0.0 1.7e-35 122.1 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO66738.1 - 5.5e-08 32.5 8.3 1e-07 31.7 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dna2 PF08696.6 AEO66738.1 - 0.015 14.5 1.0 0.029 13.6 0.7 1.3 1 0 0 1 1 1 0 DNA replication factor Dna2 Anoctamin PF04547.7 AEO66738.1 - 0.22 10.1 2.5 0.39 9.3 1.7 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel BRO1 PF03097.13 AEO66739.1 - 5e-134 446.7 0.5 5e-134 446.7 0.4 2.6 2 1 2 4 4 4 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 AEO66739.1 - 2.3e-93 312.4 20.8 4.4e-93 311.4 14.4 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV FlaC_arch PF05377.6 AEO66739.1 - 0.028 14.3 0.2 0.2 11.5 0.0 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1539 PF07560.6 AEO66739.1 - 0.049 13.4 3.8 0.83 9.5 0.0 3.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) DUF4407 PF14362.1 AEO66739.1 - 1.3 7.8 19.6 0.68 8.8 7.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) COG2 PF06148.6 AEO66739.1 - 1.6 8.5 8.4 0.24 11.2 0.4 3.3 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 APC_crr PF05923.7 AEO66740.1 - 0.031 13.8 0.2 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 APC cysteine-rich region FSH1 PF03959.8 AEO66741.1 - 1.1e-34 119.7 0.0 3.4e-34 118.1 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 AEO66741.1 - 2.7e-10 40.5 0.2 3.6e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 AEO66741.1 - 0.00012 21.5 0.1 0.26 10.7 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase CC PF04942.9 AEO66743.1 - 0.0077 16.0 1.0 0.0077 16.0 0.7 1.9 2 0 0 2 2 2 1 CC domain Syja_N PF02383.13 AEO66744.1 - 2.5e-90 302.5 0.0 4.7e-90 301.5 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Vac7 PF12751.2 AEO66744.1 - 5.6 5.7 9.5 10 4.8 6.6 1.5 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Zip PF02535.17 AEO66744.1 - 6.6 5.6 22.9 13 4.6 15.9 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2454 PF10521.4 AEO66745.1 - 4.7e-74 248.9 0.0 7.9e-74 248.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) HEAT_EZ PF13513.1 AEO66745.1 - 4.6 7.8 11.5 6.2 7.4 0.1 4.5 4 0 0 4 4 4 0 HEAT-like repeat PolyA_pol PF01743.15 AEO66746.1 - 6.1e-24 84.6 0.0 1.5e-23 83.3 0.0 1.7 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 AEO66746.1 - 2.2e-09 36.7 0.0 5.5e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 AEO66746.1 - 0.0025 17.6 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative MFS_1 PF07690.11 AEO66747.1 - 5.5e-42 143.7 62.4 2.2e-41 141.7 43.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO66747.1 - 1.2e-15 56.7 20.4 1.7e-15 56.2 14.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 AEO66747.1 - 2.3e-11 42.9 15.3 2.3e-11 42.9 10.6 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter DUF3377 PF11857.3 AEO66747.1 - 5.3 6.7 5.6 1.8 8.2 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) SSF PF00474.12 AEO66748.1 - 1.5e-16 60.0 22.3 2.2e-16 59.4 15.4 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Bac_luciferase PF00296.15 AEO66749.1 - 5.2e-64 216.2 6.6 7.3e-64 215.8 4.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Sec7 PF01369.15 AEO66750.1 - 2.1e-60 203.6 0.0 3.4e-60 202.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 AEO66750.1 - 6.8e-18 64.6 0.3 2.7e-10 39.9 0.0 3.7 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Anp1 PF03452.9 AEO66751.1 - 1.8e-121 404.4 0.2 1.4e-119 398.2 0.0 2.1 2 0 0 2 2 2 2 Anp1 DUF4229 PF14012.1 AEO66751.1 - 0.02 14.7 0.5 0.037 13.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Med5 PF08689.5 AEO66751.1 - 2.6 5.6 7.8 3.7 5.1 5.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 APC_CDC26 PF10471.4 AEO66751.1 - 4.7 8.0 9.4 5.1 7.9 5.6 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF1446 PF07287.6 AEO66752.1 - 2.1e-136 454.1 0.0 2.5e-136 453.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) CoA_transf_3 PF02515.12 AEO66754.1 - 2.7e-18 65.8 0.1 8.3e-13 48.0 0.0 3.2 2 1 1 3 3 3 3 CoA-transferase family III RNase_PH PF01138.16 AEO66755.1 - 2e-26 92.8 0.0 3e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 GDA1_CD39 PF01150.12 AEO66756.1 - 2e-105 352.8 0.0 2.6e-105 352.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family NUDIX PF00293.23 AEO66757.1 - 2.5e-07 30.3 0.0 4.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.10 AEO66758.1 - 8e-22 77.9 0.0 8.8e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.6 AEO66759.1 - 2.9e-102 342.2 0.0 3.2e-102 342.0 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.12 AEO66760.1 - 2.4e-15 56.0 0.0 5.2e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain RNF111_N PF15303.1 AEO66760.1 - 0.001 18.6 3.2 0.0017 17.9 2.2 1.4 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase Arkadia N-terminus Mei4 PF13971.1 AEO66760.1 - 0.056 12.3 0.6 0.074 11.9 0.4 1.1 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 DUF755 PF05501.6 AEO66760.1 - 0.1 12.6 7.5 0.15 12.1 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) zf-C3HC4_3 PF13920.1 AEO66761.1 - 5.5e-08 32.3 12.7 9.3e-08 31.6 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FAM24 PF15193.1 AEO66761.1 - 2.1 8.5 9.0 4.4 7.5 6.2 1.5 1 0 0 1 1 1 0 FAM24 family RRM_1 PF00076.17 AEO66762.1 - 7.1e-26 89.6 0.5 1.2e-11 44.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO66762.1 - 5.9e-16 58.1 0.1 1.7e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO66762.1 - 9.9e-15 54.1 0.1 2.8e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.1 AEO66762.1 - 0.087 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) ATP-synt_D PF01813.12 AEO66763.1 - 3.9e-62 209.3 4.1 4.8e-62 209.0 2.8 1.1 1 0 0 1 1 1 1 ATP synthase subunit D GAS PF13851.1 AEO66763.1 - 0.066 12.3 5.4 0.43 9.7 0.0 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Viral_P18 PF04521.8 AEO66763.1 - 4.6 6.7 5.7 4.8 6.6 0.2 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein TPR_12 PF13424.1 AEO66764.1 - 4.2e-12 45.8 0.8 0.22 11.5 0.0 7.2 6 1 1 7 7 7 3 Tetratricopeptide repeat Suf PF05843.9 AEO66764.1 - 5e-10 39.5 10.2 0.049 13.3 3.5 5.8 3 2 2 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 AEO66764.1 - 7.1e-09 35.5 14.7 1.4 9.7 0.0 10.6 11 2 2 13 13 10 2 Tetratricopeptide repeat TPR_11 PF13414.1 AEO66764.1 - 2.5e-07 30.2 4.9 0.56 9.9 0.0 6.5 8 0 0 8 8 8 2 TPR repeat Mad3_BUB1_I PF08311.7 AEO66764.1 - 4e-05 23.3 9.0 0.98 9.2 0.1 6.4 7 0 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_15 PF13429.1 AEO66764.1 - 6.5e-05 22.1 14.7 0.00023 20.3 0.7 5.0 4 2 2 6 6 6 2 Tetratricopeptide repeat RPN7 PF10602.4 AEO66764.1 - 0.00034 20.0 0.9 0.0035 16.7 0.1 3.1 4 1 0 4 4 4 1 26S proteasome subunit RPN7 TPR_8 PF13181.1 AEO66764.1 - 0.00053 19.5 3.3 0.87 9.5 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 AEO66764.1 - 0.00097 19.7 13.0 0.06 14.0 0.0 6.9 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 AEO66764.1 - 0.0022 17.6 5.4 0.89 9.5 0.0 6.4 8 0 0 8 8 7 1 Tetratricopeptide repeat NRDE-2 PF08424.5 AEO66764.1 - 0.0024 16.8 12.7 0.11 11.3 0.2 5.6 2 2 3 5 5 5 2 NRDE-2, necessary for RNA interference TPR_2 PF07719.12 AEO66764.1 - 0.012 15.4 23.6 0.17 11.8 0.0 7.0 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 AEO66764.1 - 0.021 15.2 0.3 0.85 10.2 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 AEO66764.1 - 0.069 13.3 5.0 15 6.0 0.0 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat PPR_3 PF13812.1 AEO66764.1 - 0.086 13.1 0.0 1.4 9.4 0.0 3.2 2 0 0 2 2 1 0 Pentatricopeptide repeat domain TPR_6 PF13174.1 AEO66764.1 - 0.77 10.3 7.5 30 5.3 0.0 6.3 5 1 1 6 6 6 0 Tetratricopeptide repeat adh_short PF00106.20 AEO66766.1 - 1.6e-35 122.4 1.3 3.1e-35 121.5 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO66766.1 - 5.4e-14 52.2 0.0 9.6e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO66766.1 - 1.2e-13 51.4 0.0 1.6e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Lin0512_fam PF09585.5 AEO66766.1 - 0.013 15.0 0.1 0.036 13.6 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) Eno-Rase_NADH_b PF12242.3 AEO66766.1 - 0.031 14.0 0.1 0.075 12.8 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MFS_1 PF07690.11 AEO66767.1 - 3e-11 42.6 34.1 2.5e-09 36.3 21.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4245 PF14030.1 AEO66767.1 - 0.04 13.6 0.4 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) Pox_A14 PF05767.7 AEO66767.1 - 0.16 11.9 0.4 2 8.3 0.0 2.6 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 PrgI PF12666.2 AEO66767.1 - 1.5 9.0 0.0 1.5 9.0 0.0 3.7 4 0 0 4 4 4 0 PrgI family protein Fungal_trans PF04082.13 AEO66768.1 - 4e-29 101.2 0.1 7.7e-29 100.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO66768.1 - 3.2e-07 30.1 12.6 5.5e-07 29.3 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3129 PF11327.3 AEO66772.1 - 1.3e-61 207.6 12.0 1.5e-61 207.4 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) PEMT PF04191.8 AEO66773.1 - 4.8e-57 190.5 10.0 5.7e-36 122.8 1.3 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase TPR_MLP1_2 PF07926.7 AEO66774.1 - 0.037 13.7 5.5 0.055 13.2 3.8 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein eIF3g PF12353.3 AEO66775.1 - 1.6e-45 154.1 1.1 2.6e-45 153.4 0.7 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 AEO66775.1 - 3.4e-16 58.6 0.1 5.9e-16 57.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO66775.1 - 3.2e-13 49.4 0.1 6e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO66775.1 - 1.5e-07 31.1 0.1 3.6e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2046 PF09755.4 AEO66778.1 - 0.00069 18.5 3.0 0.00069 18.5 2.1 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Syntaxin_2 PF14523.1 AEO66778.1 - 0.0077 16.2 4.6 0.13 12.2 0.5 2.2 2 0 0 2 2 2 1 Syntaxin-like protein IncA PF04156.9 AEO66778.1 - 0.01 15.4 7.8 0.76 9.3 1.7 2.2 2 0 0 2 2 2 0 IncA protein MerR-DNA-bind PF09278.6 AEO66778.1 - 0.019 15.3 1.4 0.019 15.3 1.0 2.4 2 0 0 2 2 2 0 MerR, DNA binding FlxA PF14282.1 AEO66778.1 - 0.097 12.6 12.1 0.099 12.5 1.8 2.8 2 1 0 2 2 2 0 FlxA-like protein DUF972 PF06156.8 AEO66778.1 - 0.13 12.6 5.1 2.8 8.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Tropomyosin_1 PF12718.2 AEO66778.1 - 0.13 12.1 6.7 0.41 10.4 0.2 2.3 2 0 0 2 2 2 0 Tropomyosin like DivIVA PF05103.8 AEO66778.1 - 0.16 12.0 9.0 0.11 12.5 0.5 2.2 2 0 0 2 2 2 0 DivIVA protein Striatin PF08232.7 AEO66778.1 - 0.42 10.9 8.7 3.1 8.0 1.2 2.4 2 0 0 2 2 2 0 Striatin family Pox_A_type_inc PF04508.7 AEO66778.1 - 0.46 10.4 7.8 0.37 10.7 0.7 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat SlyX PF04102.7 AEO66778.1 - 1.4 9.3 8.0 4.1 7.8 1.9 2.5 2 0 0 2 2 2 0 SlyX Spc24 PF08286.6 AEO66778.1 - 2.2 7.9 6.9 8.2 6.1 0.2 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TBPIP PF07106.8 AEO66778.1 - 3.8 7.0 7.0 5.8 6.4 0.1 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1049 PF06305.6 AEO66778.1 - 4.5 6.8 7.8 7 6.2 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DivIC PF04977.10 AEO66778.1 - 4.5 6.8 8.4 3 7.3 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator DAO PF01266.19 AEO66779.1 - 1.1e-51 175.8 8.3 1.2e-51 175.7 5.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO66779.1 - 1.8e-05 24.6 1.3 4.1e-05 23.5 0.9 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AEO66779.1 - 3.2e-05 24.0 0.6 0.00067 19.7 0.4 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO66779.1 - 0.065 13.0 0.4 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO66779.1 - 0.067 12.2 0.1 0.15 11.0 0.1 1.5 1 0 0 1 1 1 0 Thi4 family DUF2415 PF10313.4 AEO66780.1 - 7.5e-15 54.3 0.0 1.6e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) AKAP7_RIRII_bdg PF10470.4 AEO66780.1 - 0.21 11.4 1.6 0.68 9.7 0.9 1.9 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein HSP70 PF00012.15 AEO66781.1 - 3.3e-268 890.5 17.0 3.9e-268 890.3 11.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AEO66781.1 - 3.4e-15 55.4 5.2 2.7e-13 49.2 1.3 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 AEO66781.1 - 4.1e-06 26.5 0.4 0.00014 21.5 0.0 2.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 AEO66781.1 - 0.00032 20.5 5.7 19 5.1 3.9 4.6 1 1 0 1 1 1 1 Cell division protein FtsA UVR PF02151.14 AEO66781.1 - 0.0057 16.1 0.4 0.016 14.7 0.3 1.8 1 0 0 1 1 1 1 UvrB/uvrC motif Hydantoinase_A PF01968.13 AEO66781.1 - 2.6 7.0 9.3 1.8 7.6 0.0 3.4 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase PPR_2 PF13041.1 AEO66783.1 - 1e-13 51.0 0.4 0.00011 22.1 0.0 5.6 3 2 2 5 5 5 3 PPR repeat family PPR_3 PF13812.1 AEO66783.1 - 1.2e-13 50.1 2.3 0.036 14.3 0.0 7.2 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.15 AEO66783.1 - 2.3e-13 49.1 0.2 0.015 15.2 0.0 6.9 6 0 0 6 6 6 3 PPR repeat TPR_14 PF13428.1 AEO66783.1 - 8.7e-07 29.0 17.4 0.094 13.3 0.0 8.0 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO66783.1 - 4.6e-05 23.9 6.6 0.00071 20.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR_1 PF12854.2 AEO66783.1 - 0.0001 21.7 0.0 1.6 8.2 0.0 4.5 4 0 0 4 4 4 1 PPR repeat TPR_19 PF14559.1 AEO66783.1 - 0.0079 16.5 8.8 0.15 12.4 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 AEO66783.1 - 0.035 13.7 0.1 0.58 9.8 0.0 3.1 2 0 0 2 2 2 0 TPR repeat TPR_7 PF13176.1 AEO66783.1 - 0.039 13.7 0.9 7.7 6.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 AEO66783.1 - 0.08 13.0 0.2 3.9 7.6 0.0 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 AEO66783.1 - 0.11 12.4 7.2 11 6.1 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat RRM_6 PF14259.1 AEO66784.1 - 1.5e-12 47.2 0.1 4.7e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO66784.1 - 1.3e-08 34.5 0.1 4.8e-08 32.7 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO66784.1 - 5e-08 32.4 0.8 2.7e-07 30.1 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 AEO66784.1 - 3.9e-07 30.0 0.0 8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.19 AEO66784.1 - 0.00011 21.7 2.6 0.00019 21.0 1.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1330 PF07045.6 AEO66784.1 - 0.0072 16.1 0.1 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1330) Nup35_RRM_2 PF14605.1 AEO66784.1 - 0.02 14.6 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif AAA_23 PF13476.1 AEO66784.1 - 0.045 14.0 2.1 0.053 13.8 0.7 1.6 2 0 0 2 2 2 0 AAA domain TMCO5 PF14992.1 AEO66784.1 - 0.33 10.0 10.1 0.51 9.4 7.0 1.1 1 0 0 1 1 1 0 TMCO5 family Borrelia_P83 PF05262.6 AEO66784.1 - 4.3 5.4 10.0 6.2 4.9 6.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Mucin PF01456.12 AEO66784.1 - 8.6 6.1 26.1 25 4.6 18.1 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein MTHFR PF02219.12 AEO66785.1 - 2.1e-112 374.8 0.0 3.3e-112 374.2 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF676 PF05057.9 AEO66786.1 - 4.5e-44 150.3 0.0 1.4e-28 99.6 0.0 3.2 2 1 0 3 3 3 3 Putative serine esterase (DUF676) Lipase_3 PF01764.20 AEO66786.1 - 0.026 14.1 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.6 AEO66786.1 - 0.091 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) zf-BED PF02892.10 AEO66787.1 - 0.033 13.9 0.3 0.033 13.9 0.2 2.3 2 0 0 2 2 2 0 BED zinc finger Zn_clus PF00172.13 AEO66787.1 - 0.1 12.4 7.9 0.25 11.3 5.5 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_6 PF13912.1 AEO66787.1 - 0.23 11.4 5.1 0.068 13.1 0.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Sec5 PF15469.1 AEO66788.1 - 4.1e-35 121.1 0.0 1e-34 119.8 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 AEO66788.1 - 0.00023 20.9 2.8 0.0012 18.6 0.0 3.3 3 1 0 3 3 3 1 Vps51/Vps67 Iso_dh PF00180.15 AEO66789.1 - 4.6e-99 331.6 0.0 5.5e-99 331.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Amidase PF01425.16 AEO66790.1 - 7.4e-05 21.7 0.0 8.5e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Amidase TPR_12 PF13424.1 AEO66791.1 - 3.9e-23 81.1 15.3 6.9e-10 38.7 0.2 4.8 3 1 2 5 5 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 AEO66791.1 - 3.3e-15 54.9 12.2 5.4e-05 22.6 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 AEO66791.1 - 5.2e-15 54.0 12.0 0.00035 20.2 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 AEO66791.1 - 7.5e-13 47.9 10.9 3.6e-06 26.5 0.5 4.3 2 2 2 4 4 4 4 TPR repeat TPR_7 PF13176.1 AEO66791.1 - 1.3e-09 37.1 3.5 0.012 15.3 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO66791.1 - 1.7e-09 36.7 9.6 0.0079 15.9 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.1 AEO66791.1 - 4.8e-09 35.8 24.1 0.052 13.5 0.1 6.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 AEO66791.1 - 2.5e-06 27.7 2.4 3.1 8.1 0.0 4.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO66791.1 - 3.1e-05 24.5 11.4 2 9.1 0.0 5.2 2 2 3 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 AEO66791.1 - 0.00026 21.0 1.1 0.2 11.7 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 AEO66791.1 - 0.0003 20.7 7.2 0.5 10.6 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 AEO66791.1 - 0.00037 20.7 15.3 3.3 8.3 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 AEO66791.1 - 0.0025 18.3 11.3 17 6.4 0.0 6.0 4 2 2 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.4 AEO66791.1 - 0.019 14.3 1.0 11 5.3 0.1 4.0 2 1 1 3 3 3 0 26S proteasome subunit RPN7 DUF4398 PF14346.1 AEO66791.1 - 0.021 14.8 0.4 0.021 14.8 0.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4398) MIT PF04212.13 AEO66791.1 - 0.027 14.3 1.4 34 4.4 0.0 4.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain PPR PF01535.15 AEO66791.1 - 0.91 9.6 3.6 4.6 7.4 0.1 3.6 4 0 0 4 4 4 0 PPR repeat F-box-like PF12937.2 AEO66792.1 - 0.00047 19.8 0.1 0.001 18.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO66792.1 - 0.058 13.0 0.1 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 F-box domain SR-25 PF10500.4 AEO66793.1 - 0.06 12.8 10.5 0.061 12.7 7.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hamartin PF04388.7 AEO66793.1 - 0.37 9.4 6.1 0.37 9.4 4.2 1.0 1 0 0 1 1 1 0 Hamartin protein BSP PF04450.7 AEO66795.1 - 2.5e-78 262.2 0.0 3e-78 262.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 AEO66795.1 - 6.8e-08 32.6 0.6 7.8e-05 22.7 0.0 2.3 1 1 1 2 2 2 2 Peptidase MA superfamily SprT-like PF10263.4 AEO66795.1 - 0.054 13.1 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 SprT-like family CLASP_N PF12348.3 AEO66796.1 - 1.8e-136 452.7 0.7 1e-87 293.3 0.0 2.6 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 AEO66796.1 - 1.4e-05 24.7 0.0 3.5 7.9 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 AEO66796.1 - 0.00034 20.8 4.5 0.11 12.7 0.1 4.5 3 1 1 4 4 4 2 HEAT repeats UME PF08064.8 AEO66796.1 - 0.013 15.4 0.1 0.55 10.2 0.0 3.4 3 0 0 3 3 3 0 UME (NUC010) domain Adaptin_N PF01602.15 AEO66796.1 - 0.027 12.7 0.1 0.2 9.9 0.0 2.2 2 1 0 3 3 3 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 AEO66796.1 - 0.09 13.1 0.0 42 4.6 0.0 3.3 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region RhoGAP PF00620.22 AEO66797.1 - 3.6e-46 156.5 4.2 4.1e-46 156.3 0.0 2.6 2 1 0 2 2 2 1 RhoGAP domain LIM PF00412.17 AEO66797.1 - 1e-13 51.0 18.5 5.3e-09 36.0 1.6 2.4 2 0 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.5 AEO66797.1 - 1.1 9.2 17.0 0.72 9.8 0.8 3.9 4 0 0 4 4 4 0 Zinc ribbon domain SlyX PF04102.7 AEO66797.1 - 8.2 6.8 11.3 0.1 12.9 1.3 2.7 2 1 1 3 3 3 0 SlyX rRNA_processing PF08524.6 AEO66798.1 - 0.012 15.3 35.6 6.5 6.5 13.8 2.9 1 1 1 2 2 2 0 rRNA processing PAT1 PF09770.4 AEO66798.1 - 0.42 8.7 33.3 0.47 8.6 23.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC27 PF09507.5 AEO66798.1 - 1.1 8.3 34.0 1.6 7.8 23.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.8 AEO66798.1 - 1.9 8.2 25.2 2.3 8.0 17.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4210 PF13915.1 AEO66799.1 - 2.2e-25 88.7 0.1 4e-25 87.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 AEO66799.1 - 5.5e-20 71.0 1.4 1.1e-19 69.9 1.0 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis GTP_EFTU PF00009.22 AEO66800.1 - 9.1e-63 211.0 0.1 1.3e-62 210.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 AEO66800.1 - 6e-37 125.8 0.0 2e-36 124.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 AEO66800.1 - 3.6e-22 78.0 0.0 1.5e-21 76.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AEO66800.1 - 3e-13 49.6 1.4 1.1e-12 47.8 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 AEO66800.1 - 2.5e-12 46.4 0.0 6.8e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 AEO66800.1 - 1.6e-05 24.8 0.1 3.2e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Solute_trans_a PF03619.11 AEO66801.1 - 4e-106 354.3 7.1 4.8e-106 354.0 4.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF373 PF04123.8 AEO66801.1 - 1.6 7.6 4.0 0.52 9.2 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Frizzled PF01534.12 AEO66802.1 - 3.3 6.4 1.8 5.6 5.6 1.3 1.3 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region Na_Ca_ex PF01699.19 AEO66803.1 - 6.7e-41 139.1 34.5 7.8e-22 77.3 8.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein ASFV_J13L PF05568.6 AEO66803.1 - 0.0045 16.5 2.0 0.0099 15.4 1.4 1.6 1 0 0 1 1 1 1 African swine fever virus J13L protein DUF3608 PF12257.3 AEO66804.1 - 4.8e-75 252.0 0.0 7.8e-75 251.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 AEO66804.1 - 6.6e-30 102.6 0.1 1.5e-29 101.5 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Cation_efflux PF01545.16 AEO66805.1 - 5.6e-72 242.2 5.1 6.7e-72 241.9 3.5 1.0 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.11 AEO66805.1 - 0.0025 16.8 1.5 0.0025 16.8 1.0 1.7 2 1 0 2 2 2 1 Branched-chain amino acid transport system / permease component FNIP_N PF14636.1 AEO66807.1 - 1.4e-31 109.6 0.1 1.4e-31 109.6 0.0 4.1 4 2 0 4 4 4 1 Folliculin-interacting protein N-terminus zf-CGNR PF11706.3 AEO66807.1 - 0.075 12.5 0.6 0.16 11.4 0.4 1.5 1 0 0 1 1 1 0 CGNR zinc finger FNIP_C PF14638.1 AEO66807.1 - 0.079 12.3 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus FNIP_M PF14637.1 AEO66807.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain Lactonase PF10282.4 AEO66808.1 - 3.3e-80 269.7 0.0 3.7e-80 269.5 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Fungal_trans PF04082.13 AEO66809.1 - 1.3e-09 37.3 0.1 2.2e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO66809.1 - 4e-09 36.2 7.9 4e-09 36.2 5.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 AEO66812.1 - 3e-46 156.9 0.0 1.8e-45 154.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBP10CT PF08147.7 AEO66812.1 - 7.3e-23 80.1 0.6 1.8e-22 78.9 0.4 1.7 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 AEO66812.1 - 2.1e-22 78.7 0.1 8.5e-22 76.8 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO66812.1 - 0.0035 17.1 0.0 0.012 15.4 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DnaJ PF00226.26 AEO66813.1 - 4.8e-15 55.0 1.3 1.2e-14 53.8 0.3 2.1 2 0 0 2 2 2 1 DnaJ domain Arm PF00514.18 AEO66814.1 - 0.015 15.0 0.7 4 7.4 0.2 3.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Daxx PF03344.10 AEO66814.1 - 0.64 8.4 6.9 1.1 7.6 4.8 1.3 1 0 0 1 1 1 0 Daxx Family COPI_C PF06957.6 AEO66814.1 - 2.3 6.6 11.2 3.6 6.0 7.8 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Nop14 PF04147.7 AEO66814.1 - 4.6 5.0 9.5 13 3.5 6.6 1.7 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 AEO66814.1 - 5.7 5.9 12.0 1.9 7.5 5.9 1.8 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Dsl1_C PF11989.3 AEO66815.1 - 0.16 11.0 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal Transglut_core3 PF13471.1 AEO66816.1 - 0.07 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily zf-C2H2_4 PF13894.1 AEO66816.1 - 4.8 7.7 12.4 3 8.3 0.1 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 AEO66817.1 - 0.16 12.3 6.8 2.6 8.5 0.8 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger PT PF04886.7 AEO66818.1 - 9.1e-13 47.2 81.5 1.6e-09 36.9 23.3 4.3 3 1 2 5 5 5 2 PT repeat zf-C2H2_2 PF12756.2 AEO66818.1 - 0.0006 19.8 3.2 0.0066 16.5 0.2 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Fzo_mitofusin PF04799.8 AEO66818.1 - 0.0065 15.8 2.2 0.01 15.2 1.5 1.2 1 0 0 1 1 1 1 fzo-like conserved region zf-C2H2 PF00096.21 AEO66818.1 - 0.025 14.8 3.1 0.025 14.8 2.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF342 PF03961.8 AEO66818.1 - 0.028 12.8 0.9 0.034 12.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 AEO66818.1 - 0.048 13.3 3.6 0.073 12.7 2.5 1.2 1 0 0 1 1 1 0 Mnd1 family CENP-F_leu_zip PF10473.4 AEO66818.1 - 0.05 13.4 2.7 0.071 12.9 1.8 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Transposase_22 PF02994.9 AEO66818.1 - 0.063 11.7 3.1 0.11 10.9 2.2 1.3 1 0 0 1 1 1 0 L1 transposable element DUF848 PF05852.6 AEO66818.1 - 0.077 12.8 1.0 0.16 11.8 0.7 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4106 PF13388.1 AEO66818.1 - 0.083 11.8 23.6 0.0078 15.2 13.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) DUF4201 PF13870.1 AEO66818.1 - 0.095 12.1 4.2 0.13 11.6 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) IncA PF04156.9 AEO66818.1 - 0.12 11.9 3.5 0.15 11.6 1.9 1.5 2 0 0 2 2 2 0 IncA protein DivIC PF04977.10 AEO66818.1 - 0.12 11.8 10.4 0.31 10.5 2.5 2.2 1 1 1 2 2 2 0 Septum formation initiator Cluap1 PF10234.4 AEO66818.1 - 0.13 11.4 3.9 0.2 10.8 2.7 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF972 PF06156.8 AEO66818.1 - 0.14 12.5 2.2 0.29 11.4 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 AEO66818.1 - 0.15 12.0 8.5 0.06 13.3 1.8 2.2 1 1 1 2 2 2 0 bZIP transcription factor HALZ PF02183.13 AEO66818.1 - 0.16 11.6 6.0 0.21 11.3 1.0 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Ax_dynein_light PF10211.4 AEO66818.1 - 0.2 11.4 5.4 0.29 10.9 3.8 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain ADIP PF11559.3 AEO66818.1 - 0.22 11.4 5.9 0.45 10.4 4.1 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Med28 PF11594.3 AEO66818.1 - 0.24 11.6 1.5 0.42 10.8 1.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 28 Kinetocho_Slk19 PF12709.2 AEO66818.1 - 0.25 11.4 4.0 3.2 7.8 0.4 2.2 2 0 0 2 2 2 0 Central kinetochore-associated zf-C2H2_4 PF13894.1 AEO66818.1 - 0.3 11.4 14.7 2.7 8.5 1.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AEO66818.1 - 0.39 10.7 16.9 0.11 12.4 2.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger IFP_35_N PF07334.8 AEO66818.1 - 0.39 10.7 4.2 0.3 11.0 0.1 2.2 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Kinesin-relat_1 PF12711.2 AEO66818.1 - 0.39 11.1 2.7 0.9 9.9 0.8 1.9 1 1 1 2 2 2 0 Kinesin motor bZIP_2 PF07716.10 AEO66818.1 - 0.57 10.0 7.7 0.46 10.3 1.9 2.1 2 0 0 2 2 2 0 Basic region leucine zipper AAA_13 PF13166.1 AEO66818.1 - 0.68 8.3 6.5 0.085 11.3 1.5 1.6 2 0 0 2 2 2 0 AAA domain DUF904 PF06005.7 AEO66818.1 - 0.81 10.0 9.8 0.8 10.0 2.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) THOC7 PF05615.8 AEO66818.1 - 0.88 9.8 7.2 8.3 6.6 5.0 2.1 1 1 0 1 1 1 0 Tho complex subunit 7 Cep57_CLD_2 PF14197.1 AEO66818.1 - 1.8 8.5 5.3 9.7 6.2 0.4 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 TMF_DNA_bd PF12329.3 AEO66818.1 - 4.6 7.1 10.9 2.6 7.8 1.9 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Neisseria_TspB PF05616.8 AEO66818.1 - 6.2 5.0 11.2 8.4 4.6 7.8 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Lon_C PF05362.8 AEO66819.1 - 8.4e-68 227.7 0.1 1.5e-67 226.8 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 AEO66819.1 - 4.2e-27 95.1 0.0 9.3e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 AEO66819.1 - 1.3e-22 80.3 0.0 4.7e-22 78.6 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AEO66819.1 - 5.3e-09 35.9 0.0 1.9e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 AEO66819.1 - 2.1e-08 33.6 0.0 6.3e-08 32.1 0.0 1.9 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase IstB_IS21 PF01695.12 AEO66819.1 - 7.5e-06 25.4 0.0 1.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 AEO66819.1 - 2.3e-05 23.9 0.2 0.0025 17.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AEO66819.1 - 7.7e-05 22.7 1.4 0.0002 21.3 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_3 PF07726.6 AEO66819.1 - 0.00018 21.1 0.0 0.00039 20.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AEO66819.1 - 0.00026 21.7 0.8 0.0011 19.8 0.0 2.5 3 0 0 3 3 1 1 AAA domain RuvB_N PF05496.7 AEO66819.1 - 0.00038 19.5 0.1 0.0018 17.3 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AEO66819.1 - 0.0021 17.7 0.0 0.0081 15.8 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_2 PF07724.9 AEO66819.1 - 0.0021 17.9 0.0 0.0057 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AEO66819.1 - 0.0023 18.0 0.0 0.02 15.0 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_14 PF13173.1 AEO66819.1 - 0.0027 17.5 0.0 0.0066 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 AEO66819.1 - 0.0042 15.8 0.1 0.012 14.3 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 AEO66819.1 - 0.0086 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 AEO66819.1 - 0.017 15.4 0.0 0.017 15.4 0.0 2.5 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.7 AEO66819.1 - 0.025 13.6 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 AEO66819.1 - 0.033 14.5 0.0 0.099 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AEO66819.1 - 0.035 13.7 0.0 0.079 12.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 AEO66819.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 AEO66819.1 - 0.054 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_PrkA PF08298.6 AEO66819.1 - 0.066 11.8 0.0 0.82 8.2 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain AAA_24 PF13479.1 AEO66819.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 AEO66819.1 - 0.094 11.8 0.1 0.21 10.6 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 AEO66819.1 - 0.095 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 AEO66819.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 AEO66819.1 - 0.14 11.5 0.9 0.6 9.4 0.0 2.3 3 0 0 3 3 3 0 AAA-like domain DNA_mis_repair PF01119.14 AEO66823.1 - 4.1e-35 119.8 0.1 8.2e-35 118.8 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 AEO66823.1 - 3.8e-13 49.2 0.0 7.1e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AEO66823.1 - 1.4e-11 44.1 0.0 2.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Npa1 PF11707.3 AEO66825.1 - 1.9e-81 273.6 0.1 5.6e-81 272.0 0.0 1.8 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Arm PF00514.18 AEO66825.1 - 0.073 12.9 0.9 0.49 10.3 0.0 2.6 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat MatE PF01554.13 AEO66826.1 - 4.8e-44 149.8 19.7 1.4e-24 86.5 6.1 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 AEO66826.1 - 3.2 7.5 30.7 0.017 14.9 7.9 3.6 3 1 1 4 4 4 0 Polysaccharide biosynthesis C-terminal domain NUDIX PF00293.23 AEO66827.1 - 1e-28 99.6 0.0 1.5e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_7 PF13508.1 AEO66828.1 - 6.9e-10 38.9 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO66828.1 - 3.4e-08 33.3 0.0 7.3e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 AEO66828.1 - 5.5e-07 29.4 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO66828.1 - 8.2e-05 22.7 0.1 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO66828.1 - 0.004 16.8 0.0 0.0084 15.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 AEO66828.1 - 0.019 14.8 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase RPA_C PF08784.6 AEO66829.1 - 4e-12 46.4 0.3 6.3e-12 45.7 0.2 1.3 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 AEO66829.1 - 3.9e-08 33.0 0.1 6e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4657 PF15552.1 AEO66829.1 - 1.2 8.3 3.1 1.8 7.7 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) DUF202 PF02656.10 AEO66830.1 - 4e-19 68.5 1.2 7.6e-19 67.7 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) LtrA PF06772.6 AEO66830.1 - 0.017 14.0 0.1 0.021 13.7 0.1 1.1 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) DUF373 PF04123.8 AEO66830.1 - 0.019 14.0 0.4 0.023 13.7 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) COX4_pro_2 PF07835.7 AEO66830.1 - 0.024 14.6 1.0 0.072 13.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV Tetraspannin PF00335.15 AEO66830.1 - 0.084 12.1 1.2 0.27 10.4 0.7 1.8 2 0 0 2 2 2 0 Tetraspanin family 7TM-7TMR_HD PF07698.6 AEO66830.1 - 0.13 11.7 4.8 5.3 6.4 0.4 2.8 1 1 2 3 3 3 0 7TM receptor with intracellular HD hydrolase MARVEL PF01284.18 AEO66830.1 - 0.26 11.1 2.7 0.39 10.5 1.8 1.3 1 1 0 1 1 1 0 Membrane-associating domain MOR2-PAG1_N PF14222.1 AEO66832.1 - 9e-222 737.6 0.0 1.3e-221 737.0 0.0 1.2 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 AEO66832.1 - 4.2e-94 315.1 1.0 1.2e-93 313.6 0.7 1.9 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 AEO66832.1 - 7.4e-37 126.5 3.9 3.4e-14 51.4 0.0 3.8 2 1 1 3 3 3 3 Cell morphogenesis central region Cnd1 PF12717.2 AEO66832.1 - 0.086 12.6 2.2 0.44 10.3 0.0 3.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 FAD_binding_1 PF00667.15 AEO66833.1 - 8.9e-61 205.1 0.0 1.2e-60 204.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 AEO66833.1 - 1.5e-34 119.0 0.1 2.7e-34 118.1 0.1 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 AEO66833.1 - 3.5e-09 37.2 0.0 3.9e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 AEO66833.1 - 0.0045 17.0 0.2 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin domain RRM_1 PF00076.17 AEO66834.1 - 3e-25 87.6 0.0 6.4e-12 44.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO66834.1 - 9.3e-17 60.7 0.0 4e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO66834.1 - 1.4e-08 34.4 0.1 0.0023 17.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4586 PF15239.1 AEO66834.1 - 0.03 13.8 0.3 0.082 12.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4586) RIO1 PF01163.17 AEO66835.1 - 1.5e-40 138.5 0.0 1e-27 96.7 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 AEO66835.1 - 1.3e-32 111.6 0.0 2.4e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 AEO66835.1 - 4.6e-09 36.3 1.0 1.7e-05 24.7 0.2 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 AEO66835.1 - 9.7e-06 24.7 0.1 0.00052 19.1 0.1 2.6 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_27 PF13463.1 AEO66835.1 - 0.011 15.9 0.0 0.048 13.9 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain PC_rep PF01851.17 AEO66836.1 - 7.7e-23 79.3 21.8 1.6e-07 31.1 0.0 9.5 10 0 0 10 10 10 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 AEO66836.1 - 7e-09 35.8 1.9 0.00011 22.4 0.1 4.3 5 1 0 5 5 5 2 HEAT repeats HEAT PF02985.17 AEO66836.1 - 0.0053 16.7 0.0 31 5.0 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 AEO66836.1 - 0.022 15.2 0.7 0.65 10.5 0.0 3.5 2 1 1 3 3 3 0 HEAT-like repeat TPR_5 PF12688.2 AEO66836.1 - 0.032 14.2 0.5 5.4 7.0 0.0 3.2 2 1 1 3 3 3 0 Tetratrico peptide repeat Sec1 PF00995.18 AEO66837.1 - 1.1e-134 450.1 0.0 1.3e-134 449.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Transp_cyt_pur PF02133.10 AEO66838.1 - 4.4e-28 98.0 32.7 3.4e-27 95.1 22.6 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3938 PF13074.1 AEO66838.1 - 6.2 6.7 11.7 3.7 7.4 0.7 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF3938) RibD_C PF01872.12 AEO66839.1 - 2.9e-32 111.8 0.0 3.5e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Methyltransf_23 PF13489.1 AEO66840.1 - 1.5e-17 63.7 0.0 2.1e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO66840.1 - 4.8e-09 36.5 0.0 9.7e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO66840.1 - 3.9e-08 33.8 0.0 8.7e-07 29.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO66840.1 - 1.8e-07 30.9 0.0 4.4e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO66840.1 - 2.8e-06 27.7 0.0 2e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO66840.1 - 2.9e-05 24.3 0.0 0.00024 21.4 0.0 2.5 3 1 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO66840.1 - 0.0053 15.9 0.0 0.065 12.3 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 AEO66840.1 - 0.0065 15.9 0.0 0.014 14.8 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 AEO66840.1 - 0.011 15.7 1.7 0.1 12.5 1.2 2.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 AEO66840.1 - 0.024 14.0 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 AEO66840.1 - 0.024 13.6 0.0 0.064 12.2 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 AEO66840.1 - 0.068 12.2 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 AEO66840.1 - 0.077 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) CYSTM PF12734.2 AEO66841.1 - 0.62 10.1 70.0 1.5e+04 -12.6 48.5 4.8 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance FAD_binding_3 PF01494.14 AEO66842.1 - 2.4e-16 59.7 0.1 7.6e-16 58.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 AEO66842.1 - 2.5e-06 27.3 0.1 6e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO66842.1 - 0.0014 17.5 0.1 0.0025 16.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AEO66842.1 - 0.0061 16.4 0.6 0.015 15.2 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO66842.1 - 0.0066 15.3 1.2 0.021 13.6 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain ThiF PF00899.16 AEO66842.1 - 0.0076 16.0 0.2 0.41 10.4 0.1 2.4 2 0 0 2 2 2 1 ThiF family Pyr_redox PF00070.22 AEO66842.1 - 0.0098 16.2 0.1 0.036 14.4 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 AEO66842.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.9 AEO66842.1 - 0.018 13.6 0.3 0.03 12.9 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 AEO66842.1 - 0.03 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO66842.1 - 0.033 13.2 0.2 0.064 12.3 0.1 1.5 1 0 0 1 1 1 0 Thi4 family DUF221 PF02714.10 AEO66843.1 - 2e-102 342.3 28.9 4.6e-102 341.2 20.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AEO66843.1 - 3e-36 124.3 0.5 3e-36 124.3 0.4 2.9 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 AEO66843.1 - 6.5e-16 58.0 0.0 1.7e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 AEO66843.1 - 6.7e-10 39.3 3.5 0.00026 21.4 0.5 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) PepSY_TM_2 PF13703.1 AEO66844.1 - 0.31 11.2 2.5 0.81 9.9 0.9 2.0 2 0 0 2 2 2 0 PepSY-associated TM helix Hamartin PF04388.7 AEO66846.1 - 2.6e-38 132.2 8.2 1.1e-37 130.0 5.6 1.9 1 1 0 1 1 1 1 Hamartin protein Rad9 PF04139.8 AEO66846.1 - 0.037 13.1 5.6 0.18 10.9 0.6 2.2 1 1 0 2 2 2 0 Rad9 HJURP_C PF12347.3 AEO66846.1 - 0.13 11.8 1.6 0.76 9.3 0.0 2.8 3 0 0 3 3 3 0 Holliday junction regulator protein family C-terminal repeat TPR_MLP1_2 PF07926.7 AEO66846.1 - 2.3 7.9 37.7 22 4.7 12.8 3.8 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein EHN PF06441.7 AEO66846.1 - 2.9 7.8 7.7 0.36 10.7 0.3 2.5 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Prominin PF05478.6 AEO66846.1 - 4.6 4.6 10.9 6.6 4.1 7.6 1.1 1 0 0 1 1 1 0 Prominin DUF4066 PF13278.1 AEO66847.1 - 3.3e-21 75.2 0.7 5e-20 71.4 0.5 2.0 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 AEO66847.1 - 0.0028 17.1 0.0 0.0086 15.5 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family Metallophos_2 PF12850.2 AEO66847.1 - 0.028 14.2 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Peptidase_S51 PF03575.12 AEO66847.1 - 0.056 13.1 0.0 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 Peptidase family S51 Ribosomal_L23 PF00276.15 AEO66848.1 - 9.7e-12 44.6 0.0 1.5e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 MT-A70 PF05063.9 AEO66849.1 - 1.7e-27 96.0 0.0 2.2e-17 63.1 0.0 2.2 2 0 0 2 2 2 2 MT-A70 Methyltransf_26 PF13659.1 AEO66849.1 - 0.00032 20.6 0.1 0.0005 20.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Mito_carr PF00153.22 AEO66850.1 - 1.1e-60 201.2 0.6 3.2e-21 74.8 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein FAD_binding_1 PF00667.15 AEO66850.1 - 0.014 14.8 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain PHD_2 PF13831.1 AEO66852.1 - 7.5e-14 50.7 2.3 1.5e-13 49.8 1.6 1.5 1 0 0 1 1 1 1 PHD-finger PHD PF00628.24 AEO66852.1 - 1.9e-11 43.4 6.4 3.3e-11 42.7 4.4 1.4 1 0 0 1 1 1 1 PHD-finger AAA_16 PF13191.1 AEO66852.1 - 1.2e-10 41.7 0.4 2.9e-10 40.4 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain C1_1 PF00130.17 AEO66852.1 - 0.001 18.7 0.3 0.002 17.8 0.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 AEO66852.1 - 0.0013 18.6 0.7 0.0028 17.5 0.5 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Arch_ATPase PF01637.13 AEO66852.1 - 0.0017 18.0 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase KAP_NTPase PF07693.9 AEO66852.1 - 0.002 17.1 0.0 0.0036 16.3 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain DUF815 PF05673.8 AEO66852.1 - 0.0024 16.8 0.0 0.004 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NB-ARC PF00931.17 AEO66852.1 - 0.0025 16.7 0.0 0.0037 16.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.22 AEO66852.1 - 0.0034 17.6 0.2 0.0097 16.2 0.0 1.8 2 0 0 2 2 1 1 ABC transporter AAA PF00004.24 AEO66852.1 - 0.0058 16.8 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 AEO66852.1 - 0.0059 16.5 0.0 0.0099 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AEO66852.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 AEO66852.1 - 0.016 14.7 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Prok-RING_1 PF14446.1 AEO66852.1 - 0.022 14.5 2.5 0.046 13.4 1.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 AAA_29 PF13555.1 AEO66852.1 - 0.023 14.1 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 AEO66852.1 - 0.029 14.3 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 AEO66852.1 - 0.033 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 AEO66852.1 - 0.036 13.4 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 AEO66852.1 - 0.044 13.4 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 AEO66852.1 - 0.063 12.7 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 AEO66852.1 - 0.067 14.0 0.0 0.19 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 AEO66852.1 - 0.069 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin Miro PF08477.8 AEO66852.1 - 0.07 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Viral_helicase1 PF01443.13 AEO66852.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PIF1 PF05970.9 AEO66852.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Med3 PF11593.3 AEO66852.1 - 0.55 9.4 9.6 1 8.4 6.7 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DZR PF12773.2 AEO66852.1 - 2.8 7.8 6.7 15 5.5 4.6 2.1 1 1 0 1 1 1 0 Double zinc ribbon ORC4_C PF14629.1 AEO66853.1 - 2.8e-42 144.4 0.0 3.1e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus HGTP_anticodon2 PF12745.2 AEO66854.1 - 0.046 12.8 0.1 0.059 12.5 0.1 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs RGS PF00615.14 AEO66856.1 - 1.5e-37 128.2 1.0 6e-37 126.3 0.0 2.4 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 AEO66856.1 - 1.8e-24 85.2 0.2 3.7e-20 71.4 0.0 3.1 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HTH_3 PF01381.17 AEO66856.1 - 0.094 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix CDC73 PF05179.9 AEO66858.1 - 8.5e-41 140.1 0.0 1.8e-40 139.0 0.0 1.5 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Bystin PF05291.6 AEO66859.1 - 1.1e-124 415.3 0.0 1.4e-124 414.9 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF383 PF04063.9 AEO66860.1 - 1.4e-68 230.2 0.0 2.9e-68 229.2 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 AEO66860.1 - 6.7e-26 89.6 0.2 1.5e-25 88.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF384) DUF2674 PF10879.3 AEO66860.1 - 0.0097 15.6 0.1 2.6 7.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2674) Sugar_tr PF00083.19 AEO66861.1 - 1.8e-42 145.4 20.1 2.3e-42 145.1 13.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO66861.1 - 7.4e-19 67.6 25.0 1.1e-18 67.1 17.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily tRNA-Thr_ED PF08915.6 AEO66861.1 - 0.1 12.5 0.1 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase Fungal_trans PF04082.13 AEO66862.1 - 1.3e-27 96.3 0.0 1.9e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO66862.1 - 3.2e-09 36.5 9.4 5.1e-09 35.9 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 AEO66863.1 - 2.2e-27 95.7 29.8 8.3e-27 93.8 16.8 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO66863.1 - 2.5e-10 39.5 1.0 2.5e-10 39.5 0.7 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 AEO66863.1 - 0.0007 18.1 2.5 0.0007 18.1 1.7 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein DUF1014 PF06244.7 AEO66864.1 - 9.5e-23 80.7 7.3 2.2e-22 79.5 5.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Fzo_mitofusin PF04799.8 AEO66864.1 - 0.023 14.0 0.1 0.037 13.4 0.1 1.2 1 0 0 1 1 1 0 fzo-like conserved region UQ_con PF00179.21 AEO66865.1 - 2.6e-11 43.1 0.0 4.1e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AEO66865.1 - 0.087 12.7 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 RWD domain Hairy_orange PF07527.8 AEO66865.1 - 0.11 12.2 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Hairy Orange 2OG-FeII_Oxy_2 PF13532.1 AEO66867.1 - 2e-33 115.8 0.0 2.7e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 AEO66867.1 - 7.5e-09 35.3 2.8 1.3e-08 34.6 1.9 1.4 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.11 AEO66867.1 - 0.00069 19.0 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 CUE domain 2OG-FeII_Oxy PF03171.15 AEO66867.1 - 0.013 15.7 0.1 0.24 11.7 0.0 2.6 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 AEO66868.1 - 1.1e-27 94.8 14.0 1.4e-10 40.6 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat DEAD PF00270.24 AEO66869.1 - 2.9e-42 144.0 0.0 5.4e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO66869.1 - 2.1e-21 75.5 0.5 6.7e-21 73.9 0.2 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO66869.1 - 0.0092 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AEO66869.1 - 0.067 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3315 PF11776.3 AEO66869.1 - 1.8 8.1 4.1 1.9 8.0 1.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3315) CUE PF02845.11 AEO66870.1 - 5.4e-11 41.7 0.0 8.8e-11 41.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain Secretin_N PF03958.12 AEO66870.1 - 0.11 12.7 0.2 0.11 12.7 0.2 1.9 2 1 0 2 2 2 0 Bacterial type II/III secretion system short domain NOT2_3_5 PF04153.13 AEO66871.1 - 4.1e-32 110.8 0.5 6.3e-32 110.2 0.4 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family cobW PF02492.14 AEO66872.1 - 9.9e-45 152.1 0.3 1.2e-44 151.8 0.2 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 AEO66872.1 - 9.5e-06 25.2 0.0 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 AEO66872.1 - 0.003 17.0 0.8 0.012 15.0 0.5 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AEO66872.1 - 0.011 15.6 0.4 0.047 13.6 0.3 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 AEO66872.1 - 0.013 15.8 0.1 0.025 14.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 AEO66872.1 - 0.013 15.2 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Miro PF08477.8 AEO66872.1 - 0.027 14.9 0.6 0.19 12.2 0.0 2.3 2 1 1 3 3 3 0 Miro-like protein AAA_23 PF13476.1 AEO66872.1 - 0.037 14.3 0.1 0.062 13.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 AEO66872.1 - 0.045 12.5 1.3 1.5 7.5 0.1 2.7 3 0 0 3 3 3 0 ArgK protein AAA_10 PF12846.2 AEO66872.1 - 0.045 13.1 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 AEO66872.1 - 0.055 13.1 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 AEO66872.1 - 0.075 12.5 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 AEO66872.1 - 0.088 12.3 1.0 0.54 9.7 0.7 2.0 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 AEO66872.1 - 0.09 12.9 0.1 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 AEO66872.1 - 0.11 12.4 0.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 AEO66872.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 AEO66872.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Mob1_phocein PF03637.12 AEO66873.1 - 1.8e-25 89.6 0.2 2.8e-25 88.9 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family Fungal_trans_2 PF11951.3 AEO66874.1 - 7.1e-10 38.0 1.3 6.3e-09 34.9 0.9 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain MOSC PF03473.12 AEO66876.1 - 4.9e-13 48.7 0.0 8.3e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 AEO66876.1 - 9.8e-12 44.6 0.0 1.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain SMC_N PF02463.14 AEO66877.1 - 1.6e-71 240.0 1.5 6.2e-70 234.8 1.1 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AEO66877.1 - 1.6e-23 82.9 1.3 1.7e-22 79.6 0.2 3.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 AEO66877.1 - 1e-13 51.8 2.3 5.2e-06 26.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 AEO66877.1 - 1.8e-11 44.7 19.3 1.8e-11 44.7 13.3 6.5 3 2 2 5 5 5 1 AAA domain AAA_29 PF13555.1 AEO66877.1 - 8.3e-05 22.0 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.2 AEO66877.1 - 0.0021 17.3 27.0 0.0021 17.3 18.7 7.7 4 2 3 7 7 7 2 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 AEO66877.1 - 0.0042 16.3 39.4 0.03 13.5 1.1 6.9 3 2 5 8 8 8 4 Reovirus sigma C capsid protein GAS PF13851.1 AEO66877.1 - 0.0046 16.1 6.2 0.0046 16.1 4.3 8.1 4 2 3 7 7 7 2 Growth-arrest specific micro-tubule binding AAA_15 PF13175.1 AEO66877.1 - 3.1 6.7 32.4 0.37 9.7 8.5 4.2 3 1 0 3 3 3 0 AAA ATPase domain Arv1 PF04161.8 AEO66878.1 - 1.3e-44 152.6 0.0 1.7e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family ATP_synt_H PF05493.8 AEO66879.1 - 1.8e-26 92.0 2.9 2e-26 91.8 2.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Bax1-I PF01027.15 AEO66879.1 - 0.03 13.9 0.2 0.033 13.8 0.1 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 YfhO PF09586.5 AEO66879.1 - 0.034 12.1 0.2 0.035 12.1 0.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Git3 PF11710.3 AEO66879.1 - 0.041 13.4 0.1 0.042 13.4 0.1 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 ABC2_membrane_4 PF12730.2 AEO66879.1 - 0.05 12.7 4.3 0.063 12.4 3.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4131 PF13567.1 AEO66879.1 - 0.089 12.1 1.3 0.089 12.1 0.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1129 PF06570.6 AEO66879.1 - 0.093 12.0 0.2 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) NAD_binding_2 PF03446.10 AEO66880.1 - 5.3e-20 71.8 0.0 7.4e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 AEO66880.1 - 3.1e-09 36.9 0.0 5.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 AEO66880.1 - 0.051 13.6 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 AEO66880.1 - 0.072 12.4 0.1 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF619 PF04768.8 AEO66881.1 - 2.6e-50 170.1 0.0 7.7e-50 168.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF619) BAR_2 PF10455.4 AEO66882.1 - 4.4e-60 203.0 0.1 6.2e-60 202.5 0.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 AEO66882.1 - 8.2e-21 74.5 0.6 6.9e-20 71.5 0.4 2.0 1 1 0 1 1 1 1 BAR domain EIF4E-T PF10477.4 AEO66882.1 - 0.0038 16.1 1.7 0.0041 15.9 0.6 1.4 1 1 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E LSM PF01423.17 AEO66883.1 - 4.4e-15 54.9 0.0 6e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain RAM PF15320.1 AEO66883.1 - 0.53 10.5 8.0 0.74 10.1 5.6 1.2 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein PPR_3 PF13812.1 AEO66884.1 - 5.2e-14 51.2 3.9 0.0096 16.1 0.0 8.8 9 0 0 9 9 9 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 AEO66884.1 - 2.4e-10 40.2 0.0 0.0049 16.8 0.0 5.9 5 1 1 6 6 6 2 PPR repeat family PPR PF01535.15 AEO66884.1 - 2.8e-07 30.0 0.4 4.7 7.3 0.0 6.9 8 0 0 8 8 8 1 PPR repeat TPR_14 PF13428.1 AEO66884.1 - 0.00064 20.1 0.0 1.7 9.4 0.0 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat PPR_1 PF12854.2 AEO66884.1 - 0.0032 16.8 0.2 8.1 6.0 0.0 3.9 3 0 0 3 3 3 1 PPR repeat TPR_12 PF13424.1 AEO66884.1 - 0.005 16.7 0.2 0.2 11.6 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Fungal_trans PF04082.13 AEO66886.1 - 1.7e-44 151.6 0.0 2.6e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO66886.1 - 2.1e-08 33.9 7.0 4.5e-08 32.8 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_Ag35 PF03286.9 AEO66887.1 - 0.014 14.9 5.2 0.017 14.6 3.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein G6B PF15096.1 AEO66887.1 - 0.069 12.6 0.6 0.074 12.5 0.4 1.1 1 0 0 1 1 1 0 G6B family BSP_II PF05432.6 AEO66887.1 - 0.085 12.1 1.2 0.1 11.8 0.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Pyocin_S PF06958.7 AEO66887.1 - 0.099 13.0 0.6 0.13 12.5 0.4 1.2 1 0 0 1 1 1 0 S-type Pyocin FAM176 PF14851.1 AEO66887.1 - 0.12 11.9 0.3 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 FAM176 family TAF4 PF05236.9 AEO66887.1 - 0.21 10.8 3.9 0.15 11.2 2.0 1.3 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family TT_ORF2 PF02957.10 AEO66887.1 - 1.8 9.2 5.1 2.7 8.6 3.5 1.3 1 1 0 1 1 1 0 TT viral ORF2 DUF2413 PF10310.4 AEO66887.1 - 2.4 6.8 8.2 2.9 6.6 5.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Med3 PF11593.3 AEO66887.1 - 2.8 7.0 5.9 3 6.9 4.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HIT PF01230.18 AEO66888.1 - 2.7e-20 72.7 0.0 4.8e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 HIT domain DUF2201_N PF13203.1 AEO66888.1 - 0.0014 17.8 3.8 0.0024 17.0 2.7 1.3 1 0 0 1 1 1 1 Putative metallopeptidase domain DcpS_C PF11969.3 AEO66888.1 - 0.0026 17.9 0.3 0.04 14.1 0.2 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding TFIIA PF03153.8 AEO66888.1 - 0.011 15.6 8.2 0.013 15.4 5.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.17 AEO66888.1 - 0.063 12.2 2.5 0.075 12.0 1.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pex14_N PF04695.8 AEO66888.1 - 0.08 12.9 5.7 0.42 10.6 1.8 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 AEO66888.1 - 0.26 11.0 3.0 0.31 10.7 2.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FimP PF09766.4 AEO66888.1 - 0.33 9.9 7.0 0.21 10.6 3.9 1.3 2 0 0 2 2 2 0 Fms-interacting protein UPF0560 PF10577.4 AEO66888.1 - 0.6 8.2 6.0 0.81 7.8 4.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 BRF1 PF07741.8 AEO66888.1 - 1.2 9.3 6.1 2.7 8.2 4.2 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF4557 PF15101.1 AEO66888.1 - 1.9 8.2 7.4 3.3 7.5 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) MRI PF15325.1 AEO66888.1 - 3.7 8.5 8.0 8.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Modulator of retrovirus infection MFS_1 PF07690.11 AEO66889.1 - 2.2e-28 99.0 26.7 3e-20 72.2 9.4 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO66889.1 - 1.8e-06 26.7 3.0 1.8e-06 26.7 2.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter ATG22 PF11700.3 AEO66889.1 - 0.0088 14.5 0.1 0.0088 14.5 0.1 3.0 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like Ferrochelatase PF00762.14 AEO66890.1 - 1.3e-93 313.4 0.0 1.5e-93 313.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.11 AEO66891.1 - 1.6e-38 132.1 0.0 3.2e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 AEO66891.1 - 1.2e-35 123.0 0.0 1.7e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 AEO66891.1 - 3.6e-14 53.0 0.1 1.2e-13 51.3 0.0 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 AEO66891.1 - 1.2e-10 40.6 0.3 3.2e-10 39.2 0.2 1.8 2 0 0 2 2 2 1 SAP domain HeH PF12949.2 AEO66891.1 - 5e-05 22.7 0.7 0.00015 21.2 0.5 1.9 1 1 0 1 1 1 1 HeH/LEM domain VWA_2 PF13519.1 AEO66891.1 - 0.0011 19.0 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 AEO66891.1 - 0.0077 15.9 0.0 0.019 14.6 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain Zn_clus PF00172.13 AEO66892.1 - 3.3e-06 26.8 8.9 5.8e-06 26.1 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain La PF05383.12 AEO66893.1 - 6.7e-17 61.0 0.0 1.1e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 AEO66893.1 - 2.5e-08 33.7 0.0 5.6e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO66893.1 - 3.6e-06 26.5 0.1 9.5e-06 25.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO66893.1 - 0.00027 20.7 0.0 0.00057 19.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S4 PF01479.20 AEO66894.1 - 4.3e-16 58.0 0.0 7.9e-16 57.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 AEO66894.1 - 0.0011 18.4 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 S4 domain CDC45 PF02724.9 AEO66894.1 - 2.4 6.0 9.5 3.3 5.6 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Septin PF00735.13 AEO66895.1 - 5.7e-121 402.8 0.1 5.7e-121 402.8 0.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 AEO66895.1 - 2.6e-07 30.5 0.0 6.4e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AEO66895.1 - 4e-05 23.1 2.6 0.00055 19.4 0.0 3.0 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 AEO66895.1 - 5.8e-05 22.3 0.5 0.00049 19.3 0.3 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 AEO66895.1 - 6.2e-05 23.3 0.7 0.015 15.5 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_10 PF12846.2 AEO66895.1 - 0.00027 20.4 1.0 0.0016 17.9 0.1 2.2 2 1 0 2 2 2 1 AAA-like domain AIG1 PF04548.11 AEO66895.1 - 0.00071 18.7 1.8 0.0016 17.5 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 AEO66895.1 - 0.0011 18.8 3.3 0.47 10.2 0.0 3.8 4 0 0 4 4 4 1 Dynamin family AAA_16 PF13191.1 AEO66895.1 - 0.0012 18.8 0.3 0.011 15.6 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain Miro PF08477.8 AEO66895.1 - 0.0017 18.8 0.0 0.0091 16.4 0.0 2.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 AEO66895.1 - 0.0024 17.2 0.6 0.027 13.8 0.0 2.7 3 0 0 3 3 3 1 Ras family AAA_22 PF13401.1 AEO66895.1 - 0.004 17.3 0.0 0.023 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AEO66895.1 - 0.0064 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 AEO66895.1 - 0.011 15.2 1.9 0.017 14.5 0.0 2.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family Exonuc_VII_L PF02601.10 AEO66895.1 - 0.041 13.0 5.6 0.072 12.2 3.9 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.12 AEO66895.1 - 0.041 13.4 2.6 2.4 7.6 0.0 3.2 3 2 1 4 4 3 0 Conserved hypothetical ATP binding protein AAA_32 PF13654.1 AEO66895.1 - 0.046 12.3 9.5 0.39 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 AEO66895.1 - 0.064 12.6 0.0 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 AEO66895.1 - 0.066 12.9 2.2 0.2 11.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 AEO66895.1 - 0.084 12.4 1.1 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AEO66895.1 - 0.086 13.0 1.1 0.43 10.7 0.0 2.5 3 0 0 3 3 2 0 RNA helicase Strep_SA_rep PF06696.6 AEO66895.1 - 0.15 11.8 5.1 0.16 11.7 0.8 2.4 1 1 1 2 2 2 0 Streptococcal surface antigen repeat YlqD PF11068.3 AEO66895.1 - 0.23 11.4 10.7 0.44 10.5 7.4 1.5 1 0 0 1 1 1 0 YlqD protein V_ATPase_I PF01496.14 AEO66895.1 - 0.86 7.3 8.7 1.4 6.6 6.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 AEO66895.1 - 1.5 8.3 8.4 2.4 7.6 5.8 1.3 1 0 0 1 1 1 0 IncA protein DUF87 PF01935.12 AEO66895.1 - 4.4 7.0 7.6 2.6 7.7 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 PLA2_B PF01735.13 AEO66896.1 - 3.8e-28 97.9 0.0 7.9e-28 96.8 0.0 1.4 1 1 0 1 1 1 1 Lysophospholipase catalytic domain RE_NgoPII PF09521.5 AEO66896.1 - 0.025 13.3 0.0 0.037 12.7 0.0 1.1 1 0 0 1 1 1 0 NgoPII restriction endonuclease Patatin PF01734.17 AEO66896.1 - 0.27 11.1 1.9 3.5 7.4 0.4 2.4 2 0 0 2 2 2 0 Patatin-like phospholipase Ribonucleas_3_3 PF14622.1 AEO66897.1 - 3.4e-09 36.7 0.0 0.00071 19.5 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 AEO66897.1 - 1.4e-07 31.9 0.0 4.3e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 AEO66897.1 - 0.00035 21.0 0.0 0.00071 20.0 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribosomal_S5_C PF03719.10 AEO66897.1 - 0.11 11.8 0.0 14 5.0 0.0 3.2 3 0 0 3 3 3 0 Ribosomal protein S5, C-terminal domain Ashwin PF15323.1 AEO66898.1 - 0.12 12.3 0.6 0.15 12.0 0.4 1.1 1 0 0 1 1 1 0 Developmental protein zf-RING_2 PF13639.1 AEO66899.1 - 8e-10 38.3 0.7 8e-10 38.3 0.5 2.9 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 AEO66899.1 - 1.9e-07 31.0 1.9 2.7e-07 30.6 0.3 2.0 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AEO66899.1 - 1.6e-06 28.0 2.7 3.5e-06 26.9 0.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO66899.1 - 1.2e-05 24.8 4.5 1.8e-05 24.2 1.1 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO66899.1 - 0.00019 21.0 0.1 0.00019 21.0 0.1 3.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AEO66899.1 - 0.00035 20.2 0.3 0.00035 20.2 0.2 2.4 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 AEO66899.1 - 0.0005 19.7 0.2 0.0005 19.7 0.1 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AEO66899.1 - 0.0024 17.6 3.1 0.0033 17.2 0.3 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 AEO66899.1 - 0.018 14.8 0.1 0.042 13.6 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 AEO66899.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.2 3 0 0 3 3 2 0 RING/Ubox like zinc-binding domain DUF3446 PF11928.3 AEO66899.1 - 0.16 12.1 15.6 0.34 11.1 10.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Metallophos PF00149.23 AEO66900.1 - 1.6e-36 125.5 0.5 1.2e-29 103.1 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase TFIIA PF03153.8 AEO66901.1 - 0.46 10.3 8.9 0.56 10.0 6.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cyclin_N PF00134.18 AEO66903.1 - 0.00058 19.4 0.1 0.0092 15.5 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain CPSase_L_D2 PF02786.12 AEO66907.1 - 1.2e-112 374.3 0.1 2.1e-83 278.7 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 AEO66907.1 - 9.9e-44 149.0 0.0 2e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 AEO66907.1 - 1.1e-43 147.8 0.0 2.6e-43 146.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 AEO66907.1 - 1.2e-41 141.6 0.0 2.7e-41 140.5 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 AEO66907.1 - 1.6e-40 137.6 0.0 3.8e-40 136.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 AEO66907.1 - 3.4e-40 136.5 0.0 1.2e-19 70.4 0.0 3.0 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 AEO66907.1 - 6.7e-37 126.9 0.0 1.2e-23 83.8 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain OTCace PF00185.19 AEO66907.1 - 1.2e-30 106.4 0.0 2.8e-30 105.2 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.17 AEO66907.1 - 2.7e-22 78.5 0.0 1.4e-21 76.2 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain ATPgrasp_Ter PF15632.1 AEO66907.1 - 7.9e-22 77.4 0.0 9.6e-12 44.2 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AEO66907.1 - 1.5e-16 60.2 0.0 1e-08 34.7 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AEO66907.1 - 6.5e-16 58.3 0.2 1.2e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 AEO66907.1 - 1.7e-06 27.9 0.2 0.017 14.9 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 AEO66907.1 - 1.1e-05 25.0 0.6 0.00031 20.2 0.4 2.4 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.14 AEO66907.1 - 0.013 15.1 0.0 6.7 6.2 0.0 3.0 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.19 AEO66907.1 - 0.074 12.5 0.1 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family Ion_trans PF00520.26 AEO66909.1 - 0.051 12.8 28.8 0.62 9.2 17.9 2.6 1 1 0 1 1 1 0 Ion transport protein BAF1_ABF1 PF04684.8 AEO66909.1 - 0.4 9.4 13.1 0.88 8.3 9.1 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor HET PF06985.6 AEO66911.1 - 1.1e-24 87.1 0.0 2.9e-24 85.8 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-MYND PF01753.13 AEO66912.1 - 1.1e-05 25.2 9.2 1.6e-05 24.6 6.4 1.3 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 AEO66912.1 - 0.15 11.4 3.0 0.25 10.6 2.1 1.4 1 0 0 1 1 1 0 Life-span regulatory factor zf-Mss51 PF13824.1 AEO66912.1 - 0.37 10.6 6.7 0.71 9.7 4.7 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.11 AEO66912.1 - 2.4 7.8 6.2 4 7.1 4.3 1.3 1 0 0 1 1 1 0 HIT zinc finger TAP42 PF04177.7 AEO66914.1 - 2.9e-105 351.9 0.0 3.2e-105 351.8 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family KBP_C PF12309.3 AEO66914.1 - 0.077 11.9 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 KIF-1 binding protein C terminal RNA_pol_Rpb5_C PF01191.14 AEO66914.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain PNPOx_C PF10590.4 AEO66915.1 - 9.6e-21 73.0 3.2 3.4e-20 71.2 2.2 2.0 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 AEO66915.1 - 3.4e-12 46.2 0.1 2.1e-11 43.6 0.1 2.1 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 AEO66915.1 - 0.062 13.6 0.0 0.13 12.5 0.0 1.6 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Ribonuclease_3 PF00636.21 AEO66916.1 - 5.4e-40 136.4 0.0 6.5e-19 68.4 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 AEO66916.1 - 8.1e-22 77.5 0.0 8.2e-09 35.4 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.9 AEO66916.1 - 1.2e-20 73.1 4.2 7.5e-20 70.5 0.0 3.3 3 0 0 3 3 3 1 Dicer dimerisation domain Helicase_C PF00271.26 AEO66916.1 - 3e-14 52.6 0.0 7e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO66916.1 - 2.3e-10 40.5 0.0 4.9e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AEO66916.1 - 5.6e-09 35.7 0.0 1.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.20 AEO66916.1 - 4.8e-05 23.8 0.3 0.0048 17.4 0.6 2.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif AAA_22 PF13401.1 AEO66916.1 - 0.0072 16.4 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arylsulfotrans PF05935.6 AEO66916.1 - 0.18 10.3 0.0 0.28 9.6 0.0 1.2 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) SDA1 PF05285.7 AEO66917.1 - 1.1 8.5 11.5 1.7 7.8 8.0 1.2 1 0 0 1 1 1 0 SDA1 Peptidase_C12 PF01088.16 AEO66918.1 - 6.1e-57 192.2 0.0 7.3e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 CesT PF05932.8 AEO66918.1 - 0.029 14.2 0.1 0.076 12.8 0.0 1.7 2 0 0 2 2 2 0 Tir chaperone protein (CesT) family PGG PF13962.1 AEO66919.1 - 1.6 8.3 6.2 2.6 7.7 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function FA_desaturase PF00487.19 AEO66919.1 - 8.3 5.7 10.5 12 5.2 6.9 1.5 1 1 0 1 1 1 0 Fatty acid desaturase FAD_binding_4 PF01565.18 AEO66920.1 - 1e-18 67.1 2.4 3.7e-14 52.3 0.4 2.4 2 0 0 2 2 2 2 FAD binding domain Lamprin PF06403.6 AEO66920.1 - 0.019 14.6 1.6 0.19 11.4 0.3 2.4 2 0 0 2 2 2 0 Lamprin SUV3_C PF12513.3 AEO66921.1 - 6.2e-16 57.5 0.5 1.3e-15 56.5 0.3 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 AEO66921.1 - 1e-08 34.8 0.0 2.5e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TK PF00265.13 AEO66921.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase Synaptobrevin PF00957.16 AEO66922.1 - 1.2e-29 101.7 0.0 1.6e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 AEO66922.1 - 2.2e-19 68.8 0.0 3.4e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain adh_short PF00106.20 AEO66923.1 - 2e-13 50.6 0.0 2e-13 50.6 0.0 2.6 3 1 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 AEO66923.1 - 5.3e-09 35.9 0.9 2e-08 34.1 0.0 2.1 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 AEO66923.1 - 0.00032 20.2 0.0 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO66923.1 - 0.0023 17.9 0.1 0.0046 16.9 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding E1-N PF14463.1 AEO66923.1 - 0.0065 16.0 0.1 0.014 14.9 0.1 1.6 1 0 0 1 1 1 1 E1 N-terminal domain Peptidase_S30 PF01577.11 AEO66923.1 - 6.3 6.1 10.8 9.4 5.5 7.5 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease G-patch PF01585.18 AEO66924.1 - 1.5e-07 31.0 0.1 2.5e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 AEO66924.1 - 0.022 14.5 0.1 0.071 12.9 0.1 1.9 1 0 0 1 1 1 0 DExH-box splicing factor binding site zf-HC5HC2H_2 PF13832.1 AEO66924.1 - 0.077 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 PHD-zinc-finger like domain DUF2360 PF10152.4 AEO66924.1 - 0.27 11.5 3.2 1.7 8.9 0.3 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Sec63 PF02889.11 AEO66925.1 - 2.3e-144 480.4 0.0 2.2e-96 322.8 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 AEO66925.1 - 4.6e-52 175.9 0.1 1e-27 96.7 0.2 3.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO66925.1 - 3.1e-16 59.0 0.0 6.7e-07 29.0 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 AEO66925.1 - 3.9e-15 56.1 0.0 1.6e-06 28.0 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AEO66925.1 - 4.1e-08 33.4 0.0 0.016 15.3 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 AEO66925.1 - 5e-07 29.3 0.4 0.024 14.3 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain SNF2_N PF00176.18 AEO66925.1 - 7.2e-06 25.0 0.1 0.079 11.7 0.1 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_30 PF13604.1 AEO66925.1 - 0.00016 21.3 0.0 0.1 12.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 AEO66925.1 - 0.00043 20.4 0.0 0.92 9.7 0.0 4.4 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 AEO66925.1 - 0.018 14.4 0.0 18 4.7 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 AEO66925.1 - 0.026 13.5 0.1 1.4 7.9 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin NCA2 PF08637.5 AEO66926.1 - 1.4e-89 299.8 0.2 2.1e-89 299.2 0.1 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.8 AEO66927.1 - 4.5e-16 59.2 16.9 4.5e-16 59.2 11.7 2.4 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Pterin_4a PF01329.14 AEO66928.1 - 2.9e-28 97.4 0.0 4.5e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase DUF2076 PF09849.4 AEO66928.1 - 0.0066 16.5 10.8 0.0093 16.0 7.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Calpain_inhib PF00748.14 AEO66928.1 - 0.066 13.5 4.9 0.1 12.9 3.4 1.3 1 0 0 1 1 1 0 Calpain inhibitor CPSF73-100_C PF11718.3 AEO66928.1 - 0.12 11.6 1.0 0.16 11.3 0.7 1.1 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Agouti PF05039.7 AEO66928.1 - 0.35 11.2 4.1 0.6 10.4 2.8 1.3 1 0 0 1 1 1 0 Agouti protein Dishevelled PF02377.10 AEO66928.1 - 6.3 7.0 7.2 14 5.9 5.0 1.6 1 0 0 1 1 1 0 Dishevelled specific domain bZIP_1 PF00170.16 AEO66929.1 - 1.4e-07 31.3 9.2 1.5e-06 28.0 6.4 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AEO66929.1 - 0.015 15.0 9.6 5.7 6.8 6.6 2.3 1 1 0 1 1 1 0 Basic region leucine zipper HALZ PF02183.13 AEO66929.1 - 0.039 13.6 0.1 0.062 13.0 0.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF3158 PF11358.3 AEO66929.1 - 0.062 12.7 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) dsrm PF00035.20 AEO66929.1 - 0.34 11.5 2.3 0.61 10.6 0.8 2.1 2 0 0 2 2 2 0 Double-stranded RNA binding motif Adeno_PIX PF03955.9 AEO66929.1 - 1.5 9.4 5.9 0.16 12.4 0.8 1.9 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Actin PF00022.14 AEO66930.1 - 6.1e-56 189.5 0.0 1.3e-33 116.0 0.0 2.1 2 0 0 2 2 2 2 Actin IR1-M PF12185.3 AEO66930.1 - 0.038 13.7 0.4 0.16 11.7 0.3 2.0 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain DASH_Dad4 PF08650.5 AEO66931.1 - 9.6e-29 99.1 7.3 1e-28 98.9 5.1 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 AEO66931.1 - 0.036 13.7 3.6 0.046 13.4 2.5 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 GM_CSF PF01109.12 AEO66931.1 - 0.083 12.8 0.5 0.095 12.6 0.4 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor V-SNARE_C PF12352.3 AEO66931.1 - 0.25 11.4 1.7 0.38 10.8 0.7 1.6 1 1 1 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus YL1_C PF08265.6 AEO66932.1 - 4e-16 58.2 0.0 6e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF3580 PF12117.3 AEO66932.1 - 0.0032 17.4 0.4 0.0056 16.6 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3580) Got1 PF04178.7 AEO66934.1 - 3.8e-18 65.6 10.8 4.3e-18 65.5 7.5 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 AEO66934.1 - 0.031 13.9 4.0 0.089 12.4 2.8 1.8 1 0 0 1 1 1 0 YrhK-like protein Profilin PF00235.14 AEO66935.1 - 3e-39 133.8 0.3 3.4e-39 133.6 0.2 1.0 1 0 0 1 1 1 1 Profilin DUF2233 PF09992.4 AEO66935.1 - 0.046 13.7 0.1 0.05 13.6 0.0 1.1 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2233) AAA PF00004.24 AEO66938.1 - 9.2e-52 174.7 0.0 3.2e-37 127.6 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AEO66938.1 - 1.5e-09 38.0 0.1 2.1e-05 24.5 0.2 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 AEO66938.1 - 1.5e-07 31.0 3.6 0.07 12.5 0.3 3.9 2 2 2 4 4 4 2 AAA domain AAA_28 PF13521.1 AEO66938.1 - 8.8e-07 29.0 0.0 0.00011 22.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AEO66938.1 - 3.6e-05 22.9 0.0 0.0088 15.1 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 AEO66938.1 - 5.1e-05 23.0 0.2 0.11 12.1 0.0 3.2 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 AEO66938.1 - 9.5e-05 22.0 3.0 0.076 12.7 0.0 4.1 4 1 0 4 4 3 2 Part of AAA domain AAA_14 PF13173.1 AEO66938.1 - 0.00027 20.8 0.0 0.5 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 AEO66938.1 - 0.00096 19.3 5.8 0.51 10.4 1.1 4.0 3 2 1 4 4 3 1 AAA domain RNA_helicase PF00910.17 AEO66938.1 - 0.0012 18.9 0.0 1.9 8.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 AEO66938.1 - 0.0018 17.9 3.9 0.046 13.3 0.2 3.3 2 1 1 3 3 3 1 NACHT domain AAA_2 PF07724.9 AEO66938.1 - 0.003 17.5 0.0 0.25 11.2 0.0 2.9 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 AEO66938.1 - 0.0097 15.3 0.0 4.8 6.5 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Vps4_C PF09336.5 AEO66938.1 - 0.013 15.4 0.0 0.14 12.0 0.0 2.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.16 AEO66938.1 - 0.013 14.6 0.3 0.68 9.0 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 AEO66938.1 - 0.02 15.1 0.0 0.062 13.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 AEO66938.1 - 0.03 14.6 0.7 0.16 12.2 0.3 2.0 2 1 0 2 2 1 0 ABC transporter AAA_33 PF13671.1 AEO66938.1 - 0.049 13.4 0.0 3.8 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 AEO66938.1 - 0.074 13.1 0.0 12 5.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 AEO66938.1 - 0.096 12.1 0.0 3 7.2 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.8 AEO66938.1 - 0.11 11.2 0.0 0.83 8.2 0.0 2.0 2 0 0 2 2 2 0 TIP49 C-terminus AFG1_ATPase PF03969.11 AEO66938.1 - 0.12 11.1 0.0 0.82 8.4 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase Bac_DnaA PF00308.13 AEO66938.1 - 0.16 11.6 0.3 0.78 9.3 0.2 2.2 1 1 0 1 1 1 0 Bacterial dnaA protein Arch_ATPase PF01637.13 AEO66938.1 - 0.18 11.4 0.1 3.6 7.2 0.1 2.6 2 1 0 2 2 2 0 Archaeal ATPase Rad17 PF03215.10 AEO66938.1 - 0.34 9.5 0.0 0.52 8.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein KAP_NTPase PF07693.9 AEO66938.1 - 0.61 9.0 1.3 6.9 5.5 0.2 2.2 2 0 0 2 2 2 0 KAP family P-loop domain SMK-1 PF04802.10 AEO66939.1 - 6.6e-77 257.4 0.2 6.6e-77 257.4 0.2 2.2 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Arm PF00514.18 AEO66939.1 - 0.023 14.5 0.0 2.2 8.2 0.0 3.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat TFIIF_alpha PF05793.7 AEO66939.1 - 9.8 4.4 12.7 19 3.4 8.8 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4071 PF13281.1 AEO66942.1 - 0.0053 15.6 0.0 0.0092 14.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4071) PPR_3 PF13812.1 AEO66942.1 - 0.017 15.3 3.3 0.71 10.3 0.0 4.9 5 0 0 5 5 5 0 Pentatricopeptide repeat domain Mito_carr PF00153.22 AEO66943.1 - 8.6e-63 208.0 0.1 1.3e-19 69.6 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S26 PF10502.4 AEO66944.1 - 8.8e-05 22.0 0.1 0.0004 19.9 0.1 1.9 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 AEO66944.1 - 0.024 14.2 0.1 0.05 13.2 0.0 1.5 2 0 0 2 2 2 0 Peptidase S24-like EIF_2_alpha PF07541.7 AEO66945.1 - 1.2e-37 128.1 0.0 2.3e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 AEO66945.1 - 3.1e-13 49.6 0.7 5.2e-13 48.8 0.5 1.4 1 0 0 1 1 1 1 S1 RNA binding domain cNMP_binding PF00027.24 AEO66946.1 - 1.1e-39 134.0 0.6 8.4e-20 70.3 0.0 5.1 5 1 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.17 AEO66946.1 - 2.9e-19 69.8 2.3 1.2e-18 67.8 1.6 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase DUF1625 PF07787.7 AEO66946.1 - 4.6 6.4 7.7 8.6 5.5 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) Pyridoxal_deC PF00282.14 AEO66947.1 - 1.6e-106 355.8 0.0 2.2e-47 161.3 0.0 3.1 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain Anoctamin PF04547.7 AEO66948.1 - 1.5e-123 412.8 1.4 1.9e-123 412.5 1.0 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel FA_desaturase PF00487.19 AEO66948.1 - 2.3 7.5 15.1 0.041 13.3 1.6 3.1 3 0 0 3 3 3 0 Fatty acid desaturase FMN_dh PF01070.13 AEO66949.1 - 3.2e-122 407.8 1.2 4e-122 407.4 0.8 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 AEO66949.1 - 2.1e-24 85.1 0.0 4.3e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 AEO66949.1 - 2.8e-07 29.8 0.0 4.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 AEO66949.1 - 0.00085 18.5 0.2 0.0014 17.8 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 AEO66949.1 - 0.0011 17.9 2.4 0.0017 17.3 0.2 2.2 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 AEO66949.1 - 0.0029 16.8 0.5 0.53 9.5 0.0 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.9 AEO66949.1 - 0.077 12.0 0.0 5.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.7 AEO66949.1 - 0.18 10.7 0.0 2.1 7.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF561) Ras PF00071.17 AEO66950.1 - 1.8e-38 131.4 0.0 2.2e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO66950.1 - 4.2e-19 69.2 0.0 5.2e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO66950.1 - 7.3e-11 41.6 0.0 9.4e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 AEO66950.1 - 0.0027 17.6 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 AEO66950.1 - 0.0043 16.9 0.0 0.0054 16.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 AEO66950.1 - 0.0045 16.1 0.0 0.0051 15.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 AEO66950.1 - 0.0047 16.1 0.0 0.0063 15.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 AEO66950.1 - 0.011 15.6 0.1 0.018 15.0 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 AEO66950.1 - 0.018 15.0 0.4 0.11 12.4 0.3 2.1 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 AEO66950.1 - 0.03 13.5 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2411 PF10304.4 AEO66950.1 - 0.03 13.8 0.1 0.063 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) AAA_5 PF07728.9 AEO66950.1 - 0.049 13.3 0.1 0.071 12.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AEO66950.1 - 0.055 13.6 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 AEO66950.1 - 0.059 12.9 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain HTH_Tnp_Tc5 PF03221.11 AEO66951.1 - 1.3e-16 60.1 3.0 2e-05 24.3 0.0 6.0 5 1 0 5 5 5 4 Tc5 transposase DNA-binding domain Homeobox_KN PF05920.6 AEO66951.1 - 1.6e-14 53.3 0.4 4.4e-14 51.8 0.3 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 AEO66951.1 - 2.6e-06 26.9 0.9 6.3e-06 25.7 0.6 1.7 1 0 0 1 1 1 1 Homeobox domain zf-C2H2 PF00096.21 AEO66951.1 - 0.00023 21.2 12.3 0.019 15.2 2.6 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO66951.1 - 0.0003 20.9 18.5 0.012 15.8 2.9 4.4 3 1 0 3 3 3 2 C2H2-type zinc finger TF_Zn_Ribbon PF08271.7 AEO66951.1 - 1.7 7.9 8.2 2.9 7.3 1.0 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding Sensor PF13796.1 AEO66953.1 - 0.0044 16.6 4.1 0.0081 15.7 2.8 1.4 1 0 0 1 1 1 1 Putative sensor PsaN PF05479.6 AEO66953.1 - 1.1 9.2 7.0 2.6 8.0 4.8 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) DUF3439 PF11921.3 AEO66954.1 - 1.9 8.2 7.2 3.5 7.3 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Nipped-B_C PF12830.2 AEO66955.1 - 9.8e-47 159.0 5.4 1e-46 158.9 0.7 3.1 3 1 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 AEO66955.1 - 5.1e-11 42.2 1.0 5.1e-11 42.2 0.7 3.8 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 AEO66955.1 - 3.9e-07 29.6 4.4 0.21 11.7 0.0 5.1 5 0 0 5 5 5 3 HEAT repeat Cnd1 PF12717.2 AEO66955.1 - 8.8e-06 25.6 2.1 0.032 14.0 0.0 4.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 TFIIS_C PF01096.13 AEO66956.1 - 9.4e-13 47.5 1.2 9.4e-13 47.5 0.8 3.0 4 0 0 4 4 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 AEO66956.1 - 2.6e-07 30.2 3.0 2.6e-07 30.2 2.1 2.5 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit C1_1 PF00130.17 AEO66956.1 - 0.0069 16.0 5.4 0.012 15.2 0.8 2.3 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.1 AEO66956.1 - 0.013 14.9 12.4 0.97 9.0 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-ISL3 PF14690.1 AEO66956.1 - 0.044 13.8 9.0 0.41 10.7 0.1 3.1 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DZR PF12773.2 AEO66956.1 - 0.056 13.2 9.2 0.27 11.0 2.0 2.4 1 1 1 2 2 2 0 Double zinc ribbon Zn_ribbon_recom PF13408.1 AEO66956.1 - 0.17 12.1 10.4 6.2 7.1 0.1 3.2 1 1 2 3 3 3 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.5 AEO66956.1 - 0.17 11.8 0.5 0.17 11.8 0.3 3.2 3 2 0 3 3 2 0 Zinc ribbon domain Rubredoxin PF00301.15 AEO66956.1 - 0.2 11.5 3.9 25 4.8 0.0 3.1 2 1 1 3 3 3 0 Rubredoxin DUF2072 PF09845.4 AEO66956.1 - 0.27 11.1 4.3 2.3 8.1 0.1 2.2 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) HypA PF01155.14 AEO66956.1 - 0.36 10.5 8.2 1.4 8.5 0.5 2.2 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 AEO66956.1 - 0.48 10.7 10.0 1.4 9.2 0.3 3.1 2 1 0 2 2 2 0 Restriction alleviation protein Lar NOB1_Zn_bind PF08772.6 AEO66956.1 - 0.51 10.2 4.1 13 5.7 0.1 2.9 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like TerY-C PF15616.1 AEO66956.1 - 0.71 9.8 5.1 0.81 9.6 0.1 2.2 2 0 0 2 2 2 0 TerY-C metal binding domain OrfB_Zn_ribbon PF07282.6 AEO66956.1 - 0.77 9.4 11.5 0.88 9.2 1.1 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain IBR PF01485.16 AEO66956.1 - 1.2 9.0 9.5 0.46 10.4 0.7 2.3 2 1 0 2 2 2 0 IBR domain DUF1922 PF09082.5 AEO66956.1 - 8.9 6.4 7.8 11 6.2 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1922) HEAT_2 PF13646.1 AEO66957.1 - 4e-29 100.7 7.9 2.2e-15 56.7 0.2 4.0 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.11 AEO66957.1 - 4.6e-20 70.0 11.9 0.00031 20.9 0.1 6.6 6 1 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.17 AEO66957.1 - 4.1e-06 26.4 5.1 1.2 9.4 0.0 6.2 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 AEO66957.1 - 4.2e-06 27.0 15.0 0.00048 20.5 0.1 5.5 3 2 2 5 5 5 1 HEAT-like repeat Cohesin_HEAT PF12765.2 AEO66957.1 - 0.054 13.4 0.1 0.74 9.8 0.0 2.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion RuvA_C PF07499.8 AEO66957.1 - 0.076 13.1 2.7 16 5.7 0.0 3.8 3 0 0 3 3 3 0 RuvA, C-terminal domain TPR_11 PF13414.1 AEO66957.1 - 0.095 12.3 1.8 3.1 7.5 0.9 2.5 2 0 0 2 2 2 0 TPR repeat TPR_19 PF14559.1 AEO66957.1 - 7.8 6.9 7.5 4.7 7.6 0.6 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO66957.1 - 9.3 7.1 13.4 5.7 7.8 1.4 4.7 2 2 3 5 5 5 0 Tetratricopeptide repeat XPG_I_2 PF12813.2 AEO66958.1 - 4.6e-63 212.9 0.0 7e-63 212.3 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing Pribosyltran_N PF13793.1 AEO66959.1 - 9.1e-43 144.6 0.0 6.2e-41 138.7 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 AEO66959.1 - 2.1e-33 115.6 0.3 2.4e-28 99.1 0.0 2.7 3 0 0 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 AEO66959.1 - 1.1e-05 25.1 0.1 0.0068 16.1 0.0 2.9 3 0 0 3 3 3 2 Phosphoribosyl transferase domain PAP_assoc PF03828.14 AEO66960.1 - 1.9e-17 62.9 0.0 1.4e-12 47.3 0.0 2.5 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 AEO66960.1 - 0.008 16.4 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF2360 PF10152.4 AEO66960.1 - 1.9 8.7 9.3 3.7 7.8 2.1 2.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) TFIIF_alpha PF05793.7 AEO66961.1 - 0.45 8.8 52.5 6.9e+02 -1.7 36.1 2.7 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bud13 PF09736.4 AEO66962.1 - 1.1e-39 135.9 1.0 4.4e-39 134.0 0.0 2.2 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex EppA_BapA PF07268.6 AEO66963.1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Exported protein precursor (EppA/BapA) ABC_membrane PF00664.18 AEO66964.1 - 2.4e-26 92.7 24.8 2.8e-26 92.5 6.0 2.8 2 1 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 AEO66964.1 - 2.7e-19 69.8 0.0 5e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AEO66964.1 - 2.8e-07 30.8 0.0 0.0001 22.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 AEO66964.1 - 0.00037 19.8 0.1 0.099 11.8 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 AEO66964.1 - 0.0016 19.2 0.0 0.0034 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AEO66964.1 - 0.0019 17.6 0.2 0.0082 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AEO66964.1 - 0.0028 17.6 0.0 0.0078 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 AEO66964.1 - 0.0035 16.2 0.0 0.0062 15.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 AEO66964.1 - 0.0057 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 AEO66964.1 - 0.0079 16.3 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AEO66964.1 - 0.0082 16.0 0.2 0.022 14.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 AEO66964.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Dynamin family DUF258 PF03193.11 AEO66964.1 - 0.022 13.9 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 AEO66964.1 - 0.027 13.9 0.1 0.077 12.4 0.1 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 AEO66964.1 - 0.036 13.7 0.1 0.14 11.9 0.1 2.0 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 AEO66964.1 - 0.04 13.6 0.1 0.079 12.6 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 AEO66964.1 - 0.043 14.1 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 AEO66964.1 - 0.051 13.0 0.2 0.1 12.0 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 AEO66964.1 - 0.07 13.4 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 AEO66964.1 - 0.099 12.5 0.3 0.5 10.3 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.24 AEO66964.1 - 0.14 12.3 0.1 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Guanylate_kin PF00625.16 AEO66964.1 - 0.15 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase cobW PF02492.14 AEO66964.1 - 0.19 11.1 0.2 0.34 10.3 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.10 AEO66964.1 - 0.41 9.2 0.0 0.67 8.5 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein SMC_N PF02463.14 AEO66965.1 - 0.0043 16.2 0.4 0.012 14.8 0.3 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Zn_clus PF00172.13 AEO66967.1 - 9.4e-07 28.6 11.2 1.5e-06 27.9 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.10 AEO66968.1 - 2.2e-29 102.7 0.0 4.8e-29 101.6 0.0 1.5 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.17 AEO66968.1 - 1.2e-20 73.9 0.0 2.2e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.6 AEO66968.1 - 1.6e-14 53.6 0.1 4.6e-14 52.2 0.1 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 AEO66968.1 - 2.4e-13 50.3 0.1 6.6e-13 48.9 0.1 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase K_channel_TID PF07941.6 AEO66968.1 - 0.0029 17.7 6.9 0.0071 16.5 4.8 1.6 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain ThiF PF00899.16 AEO66968.1 - 0.051 13.3 0.1 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 ThiF family PhdYeFM_antitox PF02604.14 AEO66968.1 - 0.085 12.4 0.0 0.26 10.8 0.0 1.8 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system F420_oxidored PF03807.12 AEO66968.1 - 0.11 12.9 1.5 0.27 11.6 0.3 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TPPK_C PF12555.3 AEO66969.1 - 0.14 11.9 1.1 5.5 6.8 0.1 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal DUF1814 PF08843.6 AEO66971.1 - 0.012 15.4 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF1814) CW_binding_1 PF01473.15 AEO66971.1 - 1.9 8.7 7.1 0.26 11.4 1.6 2.1 2 0 0 2 2 2 0 Putative cell wall binding repeat Cyd_oper_YbgE PF09600.5 AEO66972.1 - 0.11 12.7 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Metallophos_2 PF12850.2 AEO66973.1 - 1.2e-08 34.9 0.0 3.6e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AEO66973.1 - 4.5e-05 22.9 0.2 0.0002 20.8 0.2 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase 2_5_RNA_ligase2 PF13563.1 AEO66975.1 - 9.4e-31 106.5 0.1 2.3e-30 105.3 0.0 1.7 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 AEO66975.1 - 2.6e-23 82.1 0.0 4.9e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.18 AEO66975.1 - 6.6e-13 49.1 0.0 1.2e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF504 PF04457.7 AEO66975.1 - 4.2e-10 39.6 0.0 8.8e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF504) NTP_transf_2 PF01909.18 AEO66975.1 - 0.00027 21.2 0.0 0.00069 19.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain SGT1 PF07093.6 AEO66976.1 - 0.047 12.0 0.2 0.048 12.0 0.2 1.1 1 0 0 1 1 1 0 SGT1 protein ResIII PF04851.10 AEO66977.1 - 2.3e-24 86.2 0.0 5e-24 85.1 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AEO66977.1 - 4.6e-15 55.2 0.1 1.4e-14 53.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AEO66977.1 - 2.3e-14 53.2 0.0 5.9e-14 51.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 AEO66977.1 - 0.0023 16.9 0.0 0.0048 15.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 AEO66977.1 - 0.022 14.8 0.1 0.06 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain Transglut_core PF01841.14 AEO66977.1 - 0.12 12.6 0.1 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 Transglutaminase-like superfamily BAF1_ABF1 PF04684.8 AEO66979.1 - 0.062 12.1 1.5 0.069 11.9 1.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PI3_PI4_kinase PF00454.22 AEO66980.1 - 6.3e-41 140.3 0.0 8.9e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Methyltransf_23 PF13489.1 AEO66981.1 - 3.6e-13 49.5 0.0 5.2e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO66981.1 - 1.3e-10 41.6 0.0 4e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO66981.1 - 3.3e-08 33.2 0.0 7.3e-07 28.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO66981.1 - 1.1e-06 29.0 0.0 2.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO66981.1 - 2.4e-06 28.0 0.0 4.5e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AEO66981.1 - 0.00019 20.5 0.0 0.00033 19.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 AEO66981.1 - 0.00028 20.9 0.0 0.00068 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO66981.1 - 0.0035 17.6 0.0 0.025 14.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 AEO66981.1 - 0.0092 15.9 0.0 0.037 14.0 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 AEO66981.1 - 0.02 14.0 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_29 PF03141.11 AEO66981.1 - 0.068 11.4 0.0 0.14 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 AEO66981.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain YqeY PF09424.5 AEO66982.1 - 4.6e-18 65.4 6.3 4.6e-18 65.4 4.3 1.3 1 1 0 1 1 1 1 Yqey-like protein HWE_HK PF07536.9 AEO66982.1 - 0.67 10.4 4.7 89 3.6 2.4 3.1 2 1 0 2 2 2 0 HWE histidine kinase Gly-zipper_OmpA PF13436.1 AEO66983.1 - 0.00041 20.0 3.4 0.00041 20.0 2.3 1.8 2 1 0 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain DUF4150 PF13665.1 AEO66983.1 - 0.28 11.0 8.5 1.2 9.0 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4150) REV PF00424.13 AEO66983.1 - 0.84 9.5 0.1 0.84 9.5 0.0 2.6 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) SNF2_N PF00176.18 AEO66984.1 - 2.4e-70 236.6 0.0 3.5e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO66984.1 - 1.4e-09 37.7 0.0 2.8e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 AEO66984.1 - 3.7e-06 26.8 0.0 9.9e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 HIRAN domain DEAD PF00270.24 AEO66984.1 - 6.6e-06 25.7 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 AEO66984.1 - 0.037 13.7 7.8 0.073 12.8 5.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 AEO66984.1 - 0.49 10.0 6.5 1.1 8.9 4.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cyt-b5 PF00173.23 AEO66985.1 - 2e-17 62.7 0.0 5.6e-17 61.3 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 AEO66985.1 - 8.5e-17 61.4 10.9 8.5e-17 61.4 7.6 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Pkinase PF00069.20 AEO66986.1 - 4.1e-14 52.3 0.0 8.2e-13 48.0 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO66986.1 - 1.4e-13 50.5 0.0 1.1e-12 47.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.22 AEO66987.1 - 0.0024 17.2 0.4 0.0024 17.2 0.3 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3414 PF11894.3 AEO66987.1 - 0.11 9.3 0.1 0.11 9.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3414) Plasmod_dom_1 PF09715.5 AEO66987.1 - 1.8 8.5 6.2 0.22 11.4 0.5 2.3 2 1 1 3 3 3 0 Plasmodium protein of unknown function (Plasmod_dom_1) Lon_C PF05362.8 AEO66989.1 - 6.9e-65 218.1 0.0 1.5e-64 217.0 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 AEO66989.1 - 1.3e-37 129.4 0.0 4.2e-37 127.8 0.0 1.9 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 AEO66989.1 - 3.5e-22 79.0 0.0 9.9e-22 77.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 AEO66989.1 - 7.8e-09 35.0 0.0 2.1e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 AEO66989.1 - 4.7e-07 29.6 0.0 8.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AEO66989.1 - 1.9e-06 27.8 0.0 4.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AEO66989.1 - 2e-05 24.7 0.0 0.00031 20.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 AEO66989.1 - 3.4e-05 22.6 0.0 6.7e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 AEO66989.1 - 8.7e-05 23.3 0.0 0.00032 21.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AEO66989.1 - 8.9e-05 21.6 0.0 0.001 18.2 0.0 2.5 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AEO66989.1 - 0.0032 17.4 3.8 0.0091 15.9 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 AEO66989.1 - 0.0081 16.4 0.3 0.029 14.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 AEO66989.1 - 0.0092 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 AEO66989.1 - 0.032 14.1 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase IstB_IS21 PF01695.12 AEO66989.1 - 0.034 13.5 0.1 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein MobB PF03205.9 AEO66989.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 AEO66989.1 - 0.043 12.9 0.0 0.099 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 AEO66989.1 - 0.044 13.9 0.0 0.16 12.1 0.0 2.1 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 AEO66989.1 - 0.063 12.9 0.1 1 9.0 0.0 2.4 1 1 1 2 2 2 0 NTPase AAA_25 PF13481.1 AEO66989.1 - 0.064 12.6 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hamartin PF04388.7 AEO66990.1 - 0.046 12.3 8.5 0.051 12.2 5.9 1.0 1 0 0 1 1 1 0 Hamartin protein eIF3_subunit PF08597.5 AEO66990.1 - 0.39 10.2 14.2 0.3 10.5 0.1 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF605 PF04652.11 AEO66990.1 - 1.1 8.6 20.0 1.2 8.4 13.9 1.0 1 0 0 1 1 1 0 Vta1 like FAM176 PF14851.1 AEO66990.1 - 2.2 7.9 5.3 20 4.8 1.3 2.1 2 0 0 2 2 2 0 FAM176 family DUF2034 PF10356.4 AEO66991.1 - 1.9e-27 95.6 0.0 1.8e-26 92.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Pex14_N PF04695.8 AEO66991.1 - 0.029 14.4 4.6 0.053 13.5 3.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mrr_cat PF04471.7 AEO66991.1 - 0.032 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease DUF605 PF04652.11 AEO66991.1 - 0.6 9.4 7.4 0.74 9.1 5.1 1.1 1 0 0 1 1 1 0 Vta1 like Med21 PF11221.3 AEO66992.1 - 4.9e-39 133.5 4.9 5.4e-39 133.4 3.4 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 AEO66992.1 - 0.0056 16.3 5.6 0.0068 16.1 0.9 2.7 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 GAS PF13851.1 AEO66992.1 - 0.026 13.7 2.7 0.052 12.7 1.8 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PhoU_div PF01865.11 AEO66992.1 - 0.048 12.8 1.5 0.055 12.6 1.0 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF47 Fib_alpha PF08702.5 AEO66992.1 - 0.05 13.7 0.2 0.083 13.0 0.1 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family LemA PF04011.7 AEO66992.1 - 0.1 11.7 1.6 0.15 11.1 0.9 1.5 1 1 1 2 2 2 0 LemA family APG6 PF04111.7 AEO66992.1 - 0.12 11.3 2.4 0.15 11.0 1.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 HAD_2 PF13419.1 AEO66993.1 - 9.2e-36 123.6 0.3 1.1e-35 123.3 0.2 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AEO66993.1 - 9.4e-10 39.2 0.0 1.6e-09 38.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO66993.1 - 1.5e-07 31.0 0.0 2.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.13 AEO66993.1 - 0.00027 20.6 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.2 AEO66993.1 - 0.0053 16.9 0.0 0.0063 16.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 AEO66993.1 - 0.014 15.0 0.1 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 Acid Phosphatase Rrn6 PF10214.4 AEO66994.1 - 0.26 9.3 4.0 0.45 8.5 2.8 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor KH_1 PF00013.24 AEO66995.1 - 5e-27 93.3 0.4 1.6e-07 30.8 0.1 6.6 6 0 0 6 6 6 6 KH domain KH_3 PF13014.1 AEO66995.1 - 1.5e-24 85.1 3.5 8.8e-06 25.2 0.0 5.9 6 0 0 6 6 6 5 KH domain Spc97_Spc98 PF04130.8 AEO66996.1 - 7.6e-130 433.7 0.2 1.4e-129 432.8 0.2 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family Proteasome PF00227.21 AEO66997.1 - 4.5e-57 192.4 0.1 5.5e-57 192.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AEO66997.1 - 1e-13 50.2 0.0 2.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 AEO66997.1 - 0.013 15.1 0.1 0.31 10.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) Fungal_trans_2 PF11951.3 AEO66998.1 - 8.6e-18 64.0 0.0 6.7e-14 51.2 0.0 2.7 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO66998.1 - 2e-09 37.2 10.0 3.3e-09 36.5 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO66998.1 - 3.1e-06 26.2 0.4 3.2e-05 22.9 0.3 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain YgbA_NO PF11756.3 AEO66998.1 - 0.97 9.4 5.6 13 5.8 0.1 2.5 2 0 0 2 2 2 0 Nitrous oxide-stimulated promoter Methyltransf_8 PF05148.10 AEO66999.1 - 3.2e-57 193.6 0.0 4.3e-56 189.9 0.0 2.6 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 AEO66999.1 - 4.2e-08 33.5 0.2 2.4e-07 31.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO66999.1 - 0.0002 20.9 0.7 0.75 9.3 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain NST1 PF13945.1 AEO66999.1 - 0.011 15.8 6.6 0.011 15.8 4.6 3.0 3 1 0 3 3 3 0 Salt tolerance down-regulator Methyltransf_32 PF13679.1 AEO66999.1 - 0.019 14.6 0.2 0.16 11.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain UBA PF00627.26 AEO67000.1 - 1.7e-08 34.0 0.0 2.3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 AEO67000.1 - 1.3e-05 24.6 0.1 1.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain HTH_8 PF02954.14 AEO67000.1 - 0.077 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family XPC-binding PF09280.6 AEO67001.1 - 0.086 12.3 2.8 1.4 8.4 0.0 3.1 3 1 0 3 3 3 0 XPC-binding domain Acetyltransf_1 PF00583.19 AEO67002.1 - 1.1e-08 34.9 0.0 2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO67002.1 - 2.2e-06 27.7 0.0 4.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO67002.1 - 0.0015 18.6 0.1 0.0047 17.0 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO67002.1 - 0.0035 17.2 0.0 2.5 7.9 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Pribosyltran PF00156.22 AEO67003.1 - 3e-16 59.2 1.0 5.4e-16 58.4 0.7 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Met_synt_B12 PF02965.12 AEO67003.1 - 0.048 12.8 0.1 0.45 9.6 0.0 2.0 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain NOGCT PF08155.6 AEO67004.1 - 8.6e-29 99.0 3.2 1.7e-28 98.0 2.2 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 AEO67004.1 - 3.7e-28 97.1 1.7 9e-28 95.9 0.3 2.3 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 AEO67004.1 - 9.7e-15 54.5 0.0 2.2e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO67004.1 - 3.5e-09 36.1 0.0 6.1e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 AEO67004.1 - 0.00044 20.7 0.0 0.0029 18.1 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 AEO67004.1 - 0.055 12.9 0.1 0.055 12.9 0.1 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain GDI PF00996.13 AEO67005.1 - 1.6e-184 613.3 0.0 2.1e-184 612.8 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 AEO67005.1 - 0.027 14.5 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain zf-UDP PF14569.1 AEO67005.1 - 0.064 13.0 0.1 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger MRP-L47 PF06984.8 AEO67006.1 - 7.6e-23 80.2 0.4 1.2e-22 79.6 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Fungal_trans PF04082.13 AEO67008.1 - 2.6e-18 65.8 0.1 4.5e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Spc97_Spc98 PF04130.8 AEO67009.1 - 1.6e-78 264.3 0.0 2.1e-78 264.0 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Eaf7 PF07904.8 AEO67010.1 - 3.8e-28 97.2 0.0 8.5e-28 96.1 0.0 1.5 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 SLD3 PF08639.5 AEO67010.1 - 0.17 10.4 3.7 0.26 9.8 2.5 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 Daxx PF03344.10 AEO67010.1 - 0.52 8.7 12.9 0.82 8.0 8.9 1.2 1 0 0 1 1 1 0 Daxx Family CDC27 PF09507.5 AEO67010.1 - 4.4 6.4 14.7 9 5.3 10.2 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PPP4R2 PF09184.6 AEO67010.1 - 6.2 6.2 11.0 9.3 5.6 7.6 1.2 1 0 0 1 1 1 0 PPP4R2 DASH_Ask1 PF08655.5 AEO67011.1 - 6e-33 112.4 0.1 1e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 p450 PF00067.17 AEO67012.1 - 1e-51 175.9 0.0 1.5e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rhodanese PF00581.15 AEO67013.1 - 4e-16 59.3 0.0 9.8e-16 58.1 0.0 1.6 2 0 0 2 2 2 1 Rhodanese-like domain Yip1 PF04893.12 AEO67014.1 - 1.3e-13 50.7 16.9 1.3e-13 50.7 11.7 1.6 1 1 0 1 1 1 1 Yip1 domain NADH_dh_m_C1 PF15088.1 AEO67014.1 - 2.9 7.4 4.5 3.5 7.1 0.1 3.0 3 0 0 3 3 3 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial ubiquitin PF00240.18 AEO67015.1 - 3.6e-35 119.1 0.9 4e-35 119.0 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 AEO67015.1 - 1e-18 66.7 0.4 1.1e-18 66.6 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AEO67015.1 - 2.4e-06 27.7 0.1 9.8e-06 25.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 AEO67015.1 - 0.00095 18.8 0.0 0.0011 18.7 0.0 1.0 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 AEO67015.1 - 0.0037 17.1 0.1 0.0078 16.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AEO67015.1 - 0.0094 16.1 0.1 0.011 15.8 0.1 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 AEO67015.1 - 0.058 13.4 0.0 0.17 11.9 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 AEO67015.1 - 0.18 10.0 0.6 3.1 6.0 0.2 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Tash_PEST PF07708.6 AEO67015.1 - 0.33 10.9 1.8 0.64 10.0 1.2 1.4 1 0 0 1 1 1 0 Tash protein PEST motif eIF-5a PF01287.15 AEO67017.1 - 1.7e-25 88.7 1.0 2.4e-25 88.2 0.7 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 AEO67017.1 - 2.9e-05 23.6 0.8 5.8e-05 22.6 0.6 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 AEO67017.1 - 0.019 14.7 0.3 0.048 13.5 0.0 1.8 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.7 AEO67018.1 - 2.2e-122 409.2 0.0 2.6e-122 408.9 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 AEO67018.1 - 6.5e-05 21.2 1.3 0.00011 20.4 0.9 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec3 Mer2 PF09074.5 AEO67018.1 - 0.0029 17.5 0.0 0.0075 16.2 0.0 1.7 1 0 0 1 1 1 1 Mer2 DUF1664 PF07889.7 AEO67018.1 - 0.0093 15.7 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) GAS PF13851.1 AEO67018.1 - 0.034 13.3 0.1 0.1 11.7 0.1 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 AEO67018.1 - 0.12 12.2 1.7 0.37 10.6 0.2 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 AEO67018.1 - 0.15 12.2 0.7 1.5 9.1 0.0 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RabGAP-TBC PF00566.13 AEO67019.1 - 9.6e-26 90.5 0.0 1.2e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMS1_N PF10433.4 AEO67020.1 - 6.5e-98 328.0 0.0 3.4e-97 325.6 0.0 2.1 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF3245 PF11595.3 AEO67020.1 - 1.3 9.2 2.2 2.4 8.4 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) GTP_EFTU PF00009.22 AEO67021.1 - 1e-32 113.0 0.0 3.9e-32 111.2 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 AEO67021.1 - 4.9e-18 65.0 0.0 1.4e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 AEO67021.1 - 6.7e-11 42.1 2.6 1.3e-07 31.5 0.1 3.4 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AEO67021.1 - 9.2e-07 28.8 0.0 4.8e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 AEO67021.1 - 0.0027 18.1 0.8 0.01 16.3 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein ATP_bind_1 PF03029.12 AEO67021.1 - 0.0052 16.3 0.0 0.014 14.9 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU_D4 PF14578.1 AEO67021.1 - 0.0088 15.6 0.1 0.039 13.5 0.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 4 AAA_22 PF13401.1 AEO67021.1 - 0.011 15.8 0.1 0.13 12.4 0.1 2.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AEO67021.1 - 0.096 12.6 0.0 0.096 12.6 0.0 4.0 3 1 1 4 4 4 0 AAA ATPase domain HSP70 PF00012.15 AEO67022.1 - 2.3e-166 554.2 1.6 2.3e-166 554.2 1.1 2.2 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 AEO67022.1 - 7.8e-12 44.4 0.0 4.4e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 AEO67022.1 - 0.0079 16.0 9.9 0.35 10.7 0.3 4.6 3 2 0 3 3 3 2 Cell division protein FtsA Trans_reg_C PF00486.23 AEO67022.1 - 0.078 12.9 0.2 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal IncA PF04156.9 AEO67022.1 - 0.37 10.3 9.5 2.3 7.7 0.7 2.6 2 0 0 2 2 2 0 IncA protein Chitin_synth_2 PF03142.10 AEO67023.1 - 4.8e-25 87.9 4.1 5.3e-22 77.9 2.2 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 AEO67023.1 - 2.4e-19 70.0 0.0 4.4e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 AEO67023.1 - 5.8e-19 68.5 7.4 1.9e-18 66.9 5.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 AEO67023.1 - 0.0092 15.6 0.1 4.1 7.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 MIF4G PF02854.14 AEO67024.1 - 3.1e-62 209.7 0.0 3.3e-31 108.3 0.0 3.3 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 AEO67024.1 - 9.4e-51 171.9 13.6 9.4e-51 171.9 9.4 1.9 2 0 0 2 2 2 1 Up-frameshift suppressor 2 Mo-co_dimer PF03404.11 AEO67025.1 - 1.6e-54 183.0 0.0 2.8e-54 182.2 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 AEO67025.1 - 1.9e-53 180.3 0.0 3e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Cyt-b5 PF00173.23 AEO67025.1 - 2.2e-18 65.8 0.0 4.6e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ETC_C1_NDUFA5 PF04716.9 AEO67026.1 - 5.9e-21 73.7 0.4 5.9e-21 73.7 0.3 2.2 3 0 0 3 3 3 1 ETC complex I subunit conserved region RNA_pol_I_TF PF04090.7 AEO67027.1 - 0.00017 20.9 0.0 0.39 9.9 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor Sigma70_ner PF04546.8 AEO67027.1 - 2.4 7.7 24.8 0.06 12.9 4.0 3.5 3 0 0 3 3 3 0 Sigma-70, non-essential region WD40 PF00400.27 AEO67028.1 - 9e-18 63.4 11.3 1.3e-09 37.5 0.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat PAS_3 PF08447.6 AEO67029.1 - 2.7e-14 52.9 0.0 1e-08 35.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 AEO67029.1 - 1.2e-10 41.6 0.0 0.00031 21.0 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 AEO67029.1 - 8.3e-09 35.2 0.0 0.00043 20.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 AEO67029.1 - 1.2e-05 25.2 0.0 0.011 15.7 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 AEO67029.1 - 0.00015 21.6 0.0 0.00049 20.0 0.0 1.8 2 0 0 2 2 2 1 PAS domain Na_Ca_ex PF01699.19 AEO67030.1 - 1.5e-22 79.7 20.8 1.9e-13 50.1 4.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein 7tm_7 PF08395.7 AEO67030.1 - 0.0054 15.7 0.9 0.0091 15.0 0.1 1.7 2 0 0 2 2 2 1 7tm Chemosensory receptor DEAD PF00270.24 AEO67031.1 - 7.7e-25 87.3 0.0 1.3e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 AEO67031.1 - 5.3e-12 46.1 0.5 1.5e-11 44.6 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 AEO67031.1 - 5.9e-09 35.6 0.0 1.8e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Terminase_GpA PF05876.7 AEO67031.1 - 0.033 12.5 0.0 0.049 11.9 0.0 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Ran_BP1 PF00638.13 AEO67032.1 - 4.2e-13 49.3 0.9 2.3e-05 24.4 0.1 2.5 2 0 0 2 2 2 2 RanBP1 domain Bac_GDH PF05088.7 AEO67032.1 - 0.0069 13.8 0.7 0.0094 13.4 0.5 1.1 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase REV PF00424.13 AEO67033.1 - 0.13 12.1 3.1 0.41 10.5 2.2 1.8 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) zf-RING_2 PF13639.1 AEO67034.1 - 7.8e-15 54.4 17.2 8.4e-14 51.1 4.8 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 AEO67034.1 - 1.1e-11 44.1 8.5 5.3e-09 35.5 1.6 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO67034.1 - 1.2e-06 28.0 15.8 7.1e-05 22.3 4.2 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO67034.1 - 1.4e-06 28.3 2.2 1.4e-06 28.3 1.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AEO67034.1 - 8.3e-06 25.7 15.8 2.9e-05 24.0 5.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO67034.1 - 7.8e-05 22.3 11.7 0.00018 21.1 2.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_3 PF14369.1 AEO67034.1 - 0.00024 21.0 8.4 0.00034 20.5 3.4 2.4 2 0 0 2 2 2 1 zinc-finger HypA PF01155.14 AEO67034.1 - 0.0021 17.7 0.3 0.0021 17.7 0.2 2.0 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family zf-Apc11 PF12861.2 AEO67034.1 - 0.0082 15.9 6.9 0.025 14.3 1.5 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger GCC2_GCC3 PF07699.8 AEO67034.1 - 0.016 14.7 0.2 0.016 14.7 0.1 1.8 2 0 0 2 2 1 0 GCC2 and GCC3 zf-P11 PF03854.9 AEO67034.1 - 0.019 14.4 3.1 0.041 13.3 2.2 1.6 1 0 0 1 1 1 0 P-11 zinc finger PhnA_Zn_Ribbon PF08274.7 AEO67034.1 - 0.051 13.3 2.4 3.8 7.3 0.2 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DUF2318 PF10080.4 AEO67034.1 - 0.17 11.6 0.2 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Prok-RING_4 PF14447.1 AEO67034.1 - 0.23 11.0 2.9 0.69 9.4 2.0 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Baculo_RING PF05883.6 AEO67034.1 - 0.25 11.1 4.3 0.62 9.8 0.6 2.3 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-FPG_IleRS PF06827.9 AEO67034.1 - 0.53 9.9 5.2 22 4.8 0.1 3.4 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS DZR PF12773.2 AEO67034.1 - 0.57 10.0 5.9 0.24 11.2 0.5 2.3 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_5 PF13719.1 AEO67034.1 - 1.3 8.6 8.4 7 6.3 0.0 3.7 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AEO67034.1 - 1.4 8.6 8.4 19 5.0 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-RING_4 PF14570.1 AEO67034.1 - 4.1 7.0 12.3 5.9 6.5 1.9 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.7 AEO67034.1 - 6.2 6.6 6.8 2.7 7.8 0.7 2.5 3 0 0 3 3 2 0 zinc-ribbons PHD PF00628.24 AEO67034.1 - 6.6 6.5 16.7 0.98 9.1 3.8 2.7 2 1 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 AEO67034.1 - 8.2 6.2 16.3 0.66 9.7 1.3 3.6 2 2 1 3 3 3 0 Prokaryotic RING finger family 1 Fis1_TPR_C PF14853.1 AEO67035.1 - 4.3e-26 90.5 1.2 6.1e-26 90.0 0.8 1.2 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 AEO67035.1 - 2.3e-16 58.7 0.0 3.7e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 AEO67035.1 - 0.0015 18.3 1.8 0.0026 17.5 1.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 AEO67035.1 - 0.046 14.4 0.1 0.078 13.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Spc24 PF08286.6 AEO67036.1 - 8.5e-39 131.9 0.0 1.1e-37 128.2 0.0 2.0 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Streptin-Immun PF11083.3 AEO67036.1 - 0.012 15.5 0.2 0.37 10.8 0.0 2.2 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein Reo_sigmaC PF04582.7 AEO67036.1 - 0.016 14.3 1.0 0.021 14.0 0.7 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1633 PF07794.6 AEO67036.1 - 0.016 13.1 0.1 0.022 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) AAA_27 PF13514.1 AEO67036.1 - 0.047 11.3 7.6 0.06 11.0 5.2 1.1 1 0 0 1 1 1 0 AAA domain MAGSP PF03082.9 AEO67036.1 - 0.055 12.8 0.2 0.073 12.4 0.2 1.2 1 0 0 1 1 1 0 Male accessory gland secretory protein Nsp1_C PF05064.8 AEO67036.1 - 0.097 12.3 2.2 1.6 8.3 0.4 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region HTH_WhiA PF02650.9 AEO67036.1 - 0.16 12.3 1.0 0.4 11.1 0.1 1.9 1 1 1 2 2 2 0 WhiA C-terminal HTH domain APG6 PF04111.7 AEO67036.1 - 0.2 10.7 2.6 0.28 10.2 1.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 AEO67036.1 - 0.31 10.8 4.7 0.9 9.3 1.2 2.2 1 1 1 2 2 2 0 Prefoldin subunit TMF_DNA_bd PF12329.3 AEO67036.1 - 0.39 10.5 5.7 1.1 9.0 1.8 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.1 AEO67036.1 - 0.46 10.4 3.1 0.55 10.1 1.4 1.7 1 1 0 1 1 1 0 FlxA-like protein DUF4164 PF13747.1 AEO67036.1 - 0.5 10.5 10.5 1.6 8.8 7.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Viral_P18 PF04521.8 AEO67036.1 - 0.6 9.5 6.9 0.57 9.6 0.5 2.3 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein GAS PF13851.1 AEO67036.1 - 1 8.5 3.9 1.4 8.1 0.9 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding SlyX PF04102.7 AEO67036.1 - 1.3 9.4 4.7 5.2 7.5 0.7 2.6 1 1 0 2 2 2 0 SlyX ADIP PF11559.3 AEO67036.1 - 3.4 7.5 8.9 2.2 8.1 2.8 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TatD_DNase PF01026.16 AEO67038.1 - 1.8e-29 102.7 0.0 2.9e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Fungal_trans PF04082.13 AEO67039.1 - 7.1e-26 90.6 0.4 1e-25 90.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nol1_Nop2_Fmu PF01189.12 AEO67040.1 - 4.2e-30 105.0 0.0 9.6e-20 71.1 0.0 4.5 4 1 1 5 5 5 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 AEO67040.1 - 0.0012 18.8 0.9 0.0021 18.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 AEO67040.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase GTP1_OBG PF01018.17 AEO67041.1 - 5.3e-38 130.1 2.2 9.3e-28 96.8 2.8 2.5 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 AEO67041.1 - 2.8e-21 75.6 0.0 4.1e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO67041.1 - 1.2e-06 27.9 0.1 3.7e-06 26.3 0.1 1.8 3 0 0 3 3 3 1 Ferrous iron transport protein B ABC_tran PF00005.22 AEO67041.1 - 0.039 14.2 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Arf PF00025.16 AEO67041.1 - 0.043 13.0 0.0 0.45 9.7 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family ArgK PF03308.11 AEO67041.1 - 0.048 12.4 0.1 0.53 9.0 0.0 2.2 2 1 0 2 2 2 0 ArgK protein GTP_EFTU PF00009.22 AEO67041.1 - 0.081 12.3 0.0 13 5.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 AEO67041.1 - 0.13 12.1 0.8 0.93 9.3 0.1 2.7 3 1 0 3 3 3 0 AAA domain EzrA PF06160.7 AEO67043.1 - 0.0011 17.2 13.3 0.0011 17.2 9.2 3.1 2 1 1 3 3 3 2 Septation ring formation regulator, EzrA GAS PF13851.1 AEO67043.1 - 0.0075 15.4 9.6 0.0075 15.4 6.6 4.3 2 1 2 4 4 4 1 Growth-arrest specific micro-tubule binding DUF4041 PF13250.1 AEO67043.1 - 0.11 12.0 3.2 0.25 10.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) Reo_sigmaC PF04582.7 AEO67043.1 - 0.14 11.3 2.8 1.4 8.0 0.3 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4239 PF14023.1 AEO67043.1 - 0.29 10.4 16.3 1.3 8.3 4.4 3.4 2 2 2 4 4 4 0 Protein of unknown function (DUF4239) Baculo_PEP_C PF04513.7 AEO67043.1 - 7 6.4 8.8 5.7e+02 0.2 5.2 3.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Occludin_ELL PF07303.8 AEO67043.1 - 8.8 7.1 35.8 0.049 14.3 3.9 4.1 3 2 1 4 4 4 0 Occludin homology domain RNA_pol_Rpb5_C PF01191.14 AEO67044.1 - 1.4e-35 120.7 0.2 2.4e-35 119.9 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 AEO67044.1 - 9.4e-32 109.2 0.0 1.4e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 AEO67044.1 - 0.037 13.8 0.0 0.095 12.5 0.0 1.7 2 0 0 2 2 2 0 Restriction endonuclease AAA_3 PF07726.6 AEO67044.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Metallophos PF00149.23 AEO67045.1 - 2.3e-14 53.2 1.3 4e-14 52.4 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AEO67045.1 - 8e-07 29.0 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pex2_Pex12 PF04757.9 AEO67046.1 - 1.3e-54 185.0 2.1 1.8e-54 184.6 1.5 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 AEO67046.1 - 0.0011 18.9 2.7 0.0019 18.1 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO67046.1 - 0.028 14.2 1.7 0.045 13.5 1.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 AEO67046.1 - 0.11 12.2 1.1 0.17 11.5 0.8 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 4HBT PF03061.17 AEO67047.1 - 7.3e-12 45.2 0.0 1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 AEO67047.1 - 0.0077 15.9 0.1 0.012 15.3 0.1 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily F-box-like PF12937.2 AEO67048.1 - 5e-10 38.9 0.2 1.2e-09 37.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO67048.1 - 4.1e-08 32.6 0.3 1.7e-07 30.6 0.1 2.1 2 0 0 2 2 2 1 F-box domain Fungal_trans PF04082.13 AEO67049.1 - 2.3e-62 210.1 0.1 3.3e-62 209.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 AEO67049.1 - 2.4e-06 27.5 9.3 0.00017 21.7 0.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO67049.1 - 1.3e-05 25.1 10.9 0.00043 20.4 0.7 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO67049.1 - 0.33 11.3 11.6 0.24 11.7 0.6 3.1 3 0 0 3 3 3 0 Zinc-finger double domain SAP30_Sin3_bdg PF13867.1 AEO67050.1 - 4.4e-13 48.8 1.0 1.6e-11 43.8 0.1 2.3 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Glypican PF01153.14 AEO67050.1 - 0.11 11.0 0.9 0.27 9.7 0.5 1.6 2 0 0 2 2 2 0 Glypican Tombus_movement PF05318.7 AEO67050.1 - 0.47 11.1 2.8 0.98 10.0 2.0 1.6 1 0 0 1 1 1 0 Tombusvirus movement protein CTDII PF01556.13 AEO67051.1 - 5e-30 103.2 0.6 1.6e-21 75.9 0.0 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 AEO67051.1 - 1.8e-26 91.6 1.6 3.5e-26 90.7 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 AEO67051.1 - 2.8e-11 43.2 20.0 5.4e-11 42.3 13.9 1.5 1 0 0 1 1 1 1 DnaJ central domain DUF2318 PF10080.4 AEO67051.1 - 4.2 7.1 6.4 1.7 8.4 2.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) HypA PF01155.14 AEO67051.1 - 5.2 6.7 8.5 35 4.1 0.7 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 AEO67051.1 - 8.6 6.4 8.1 9.3 6.3 0.5 3.3 2 1 1 3 3 3 0 Zinc ribbon domain MFS_1 PF07690.11 AEO67052.1 - 7.4e-33 113.7 60.2 5e-32 110.9 38.9 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO67052.1 - 3.8e-08 32.3 41.3 1.9e-07 30.0 11.1 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 AEO67052.1 - 6.2e-08 31.2 20.4 2.7e-07 29.1 14.1 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 AEO67053.1 - 4.8e-10 38.7 0.0 8e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain She2p PF11435.3 AEO67053.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 RNA binding protein She2p PHD PF00628.24 AEO67054.1 - 1e-07 31.4 8.7 2.5e-07 30.2 6.1 1.7 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 AEO67054.1 - 6.9e-05 23.2 1.2 0.00022 21.5 0.0 2.4 3 0 0 3 3 3 1 SET domain E1_DerP2_DerF2 PF02221.10 AEO67055.1 - 5.1e-26 91.5 0.2 5.9e-26 91.2 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 AEO67055.1 - 0.0011 18.9 0.1 0.0052 16.8 0.1 1.8 1 1 0 1 1 1 1 ML-like domain CopC PF04234.7 AEO67055.1 - 0.028 15.0 0.0 0.052 14.1 0.0 1.4 1 0 0 1 1 1 0 CopC domain ATP-synt_F PF01990.12 AEO67056.1 - 1.1e-32 112.2 0.1 1.3e-32 111.9 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF2418 PF10332.4 AEO67057.1 - 5.6e-36 122.8 1.2 1e-35 122.0 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Aconitase PF00330.15 AEO67059.1 - 1.7e-184 613.6 0.0 2.1e-184 613.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AEO67059.1 - 2.1e-43 147.5 0.0 4.4e-43 146.5 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Cupin_8 PF13621.1 AEO67060.1 - 3.7e-28 98.6 0.0 7.9e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 AEO67060.1 - 1.2e-08 34.6 0.0 2.5e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 AEO67060.1 - 0.0028 17.9 0.0 0.061 13.5 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Metallophos_3 PF14582.1 AEO67060.1 - 0.23 10.5 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Methyltransf_23 PF13489.1 AEO67061.1 - 7.1e-18 64.8 0.0 1e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO67061.1 - 3.2e-09 36.5 0.0 4.2e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO67061.1 - 6.8e-09 36.2 0.1 1.9e-07 31.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO67061.1 - 6.7e-08 32.9 0.0 1.1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO67061.1 - 1.3e-05 25.5 0.0 6.7e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO67061.1 - 3.2e-05 24.2 0.0 7.2e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 AEO67061.1 - 0.0018 18.3 0.1 0.0039 17.2 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 AEO67061.1 - 0.028 13.5 0.0 0.26 10.3 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 AEO67061.1 - 0.07 12.1 0.0 0.13 11.3 0.0 1.4 1 1 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 AEO67061.1 - 0.099 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CDC45 PF02724.9 AEO67062.1 - 1.9e-230 766.1 0.0 2.2e-230 765.9 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein EF-hand_1 PF00036.27 AEO67063.1 - 4.9e-25 84.8 10.5 3.9e-08 32.0 0.2 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 AEO67063.1 - 4.2e-23 79.1 3.4 1.5e-06 27.6 0.1 5.1 4 1 1 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 AEO67063.1 - 4.1e-21 74.8 4.7 9.9e-14 51.2 0.4 2.9 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 AEO67063.1 - 1.5e-17 62.0 13.8 2e-05 23.7 0.6 4.5 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 AEO67063.1 - 3.5e-16 58.5 10.3 4.1e-07 29.5 0.3 3.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 AEO67063.1 - 1.6e-08 34.2 6.5 0.0043 16.7 0.1 3.9 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 AEO67063.1 - 0.0002 21.2 1.0 0.0025 17.7 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 AEO67063.1 - 0.00031 20.7 1.8 0.38 10.7 0.1 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 AEO67063.1 - 0.0014 18.2 1.0 0.65 9.7 0.0 3.6 4 0 0 4 4 4 1 EF hand EF-hand_2 PF09068.6 AEO67063.1 - 0.0052 16.8 0.2 1 9.4 0.0 3.2 3 1 0 3 3 3 1 EF hand AMP-binding PF00501.23 AEO67064.1 - 6.1e-83 278.5 0.0 9.1e-83 277.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CdhD PF03599.11 AEO67064.1 - 0.012 14.1 0.0 0.019 13.5 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Methyltransf_16 PF10294.4 AEO67065.1 - 5.9e-12 45.3 0.0 1.7e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_12 PF08242.7 AEO67065.1 - 0.037 14.4 0.0 2.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Transglut_core PF01841.14 AEO67066.1 - 1.3e-10 41.4 0.1 2.6e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 AEO67066.1 - 0.079 12.2 0.0 0.99 8.6 0.0 2.3 2 1 0 2 2 2 0 Transglutaminase-like domain tRNA-synt_1c PF00749.16 AEO67067.1 - 2e-81 273.0 0.0 2.9e-81 272.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 AEO67067.1 - 2.1e-31 108.9 0.0 7.8e-31 107.0 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain RVT_1 PF00078.22 AEO67068.1 - 8.9e-07 28.4 0.0 1e-06 28.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 AEO67069.1 - 2e-05 24.6 0.0 2.5e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 AEO67069.1 - 0.13 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain Pox_Ag35 PF03286.9 AEO67070.1 - 0.0065 16.0 5.1 0.009 15.5 3.5 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein DUF4337 PF14235.1 AEO67070.1 - 0.016 15.0 1.9 0.02 14.7 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Glypican PF01153.14 AEO67070.1 - 0.017 13.7 0.2 0.02 13.5 0.1 1.0 1 0 0 1 1 1 0 Glypican TEBP_beta PF07404.6 AEO67070.1 - 0.019 14.1 7.4 0.023 13.8 5.1 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) DUF4448 PF14610.1 AEO67070.1 - 0.03 13.8 0.2 0.035 13.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Ribosomal_60s PF00428.14 AEO67070.1 - 0.034 14.5 11.6 0.06 13.7 8.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF912 PF06024.7 AEO67070.1 - 0.08 12.9 2.3 1.1 9.4 0.0 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FLO_LFY PF01698.11 AEO67070.1 - 0.18 10.6 2.5 0.19 10.5 1.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2413 PF10310.4 AEO67070.1 - 0.23 10.2 5.3 0.27 10.0 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RNA_polI_A34 PF08208.6 AEO67070.1 - 0.57 9.8 13.0 0.63 9.6 9.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 PBP_sp32 PF07222.7 AEO67070.1 - 1.4 8.0 5.5 2.1 7.4 3.8 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 YqfQ PF14181.1 AEO67070.1 - 2.2 8.2 7.6 3 7.8 5.3 1.2 1 0 0 1 1 1 0 YqfQ-like protein DUF1510 PF07423.6 AEO67070.1 - 2.8 7.2 12.4 4 6.7 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NARP1 PF12569.3 AEO67070.1 - 3.5 6.2 9.1 4.1 6.0 6.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PBP1_TM PF14812.1 AEO67070.1 - 8.1 6.8 17.0 3.7 7.9 0.5 2.2 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RVT_1 PF00078.22 AEO67071.1 - 0.012 15.0 0.1 0.015 14.6 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) F-box-like PF12937.2 AEO67073.1 - 2.3e-07 30.4 0.1 4.8e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO67073.1 - 2.4e-06 27.0 0.1 5.7e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain IncA PF04156.9 AEO67073.1 - 0.004 16.7 0.4 0.0086 15.6 0.3 1.6 1 0 0 1 1 1 1 IncA protein F-box-like_2 PF13013.1 AEO67073.1 - 0.0046 16.6 0.1 0.016 14.8 0.0 1.9 2 0 0 2 2 2 1 F-box-like domain Fungal_trans_2 PF11951.3 AEO67074.1 - 0.002 16.7 0.0 0.0027 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glycos_transf_4 PF00953.16 AEO67075.1 - 8.6e-33 113.3 10.4 8.6e-33 113.3 7.2 2.3 2 1 0 2 2 2 1 Glycosyl transferase family 4 WD40 PF00400.27 AEO67076.1 - 4.2e-17 61.3 4.0 1.3e-05 24.8 0.0 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat GRA6 PF05084.8 AEO67077.1 - 0.13 11.7 1.5 0.22 11.0 1.1 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) MFS_1 PF07690.11 AEO67078.1 - 1.6e-06 27.0 6.4 2.2e-06 26.6 4.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CDC45 PF02724.9 AEO67078.1 - 2.6 5.9 5.6 3.5 5.5 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 AEO67078.1 - 9.9 4.4 7.7 13 4.1 5.3 1.0 1 0 0 1 1 1 0 Daxx Family AIG2 PF06094.7 AEO67081.1 - 9.9e-09 35.6 0.1 1.9e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family CAP_N PF01213.14 AEO67081.1 - 3.7 6.7 4.9 6 6.0 3.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FKBP_C PF00254.23 AEO67082.1 - 5.3e-23 80.8 0.0 6.2e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ThiF PF00899.16 AEO67083.1 - 7e-52 174.8 0.0 3e-33 114.5 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 AEO67083.1 - 2.5e-37 127.8 0.0 1.1e-35 122.5 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 AEO67083.1 - 3.3e-37 125.8 4.3 5.2e-27 93.2 0.1 2.8 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 AEO67083.1 - 3.4e-24 83.9 1.9 4.4e-21 73.9 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site E3_binding PF02817.12 AEO67083.1 - 0.019 14.5 0.9 0.26 10.9 0.2 2.4 2 0 0 2 2 2 0 e3 binding domain NMU PF02070.10 AEO67083.1 - 0.16 11.5 1.3 4.6 6.8 0.1 2.5 2 0 0 2 2 2 0 Neuromedin U GST_N_2 PF13409.1 AEO67084.1 - 2.1e-23 82.1 0.0 8e-23 80.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO67084.1 - 8e-15 54.4 0.2 2.4e-14 52.9 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 AEO67084.1 - 2.2e-05 24.5 0.1 0.0017 18.5 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 AEO67084.1 - 7.2e-05 22.7 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AEO67084.1 - 0.0036 17.7 0.1 0.0075 16.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Chitin_synth_2 PF03142.10 AEO67085.1 - 4.2e-258 857.0 1.3 6.5e-258 856.4 0.9 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 AEO67085.1 - 5.9e-166 553.4 0.0 7.7e-166 553.0 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 AEO67085.1 - 1.5e-18 66.2 0.1 9.7e-18 63.6 0.1 2.2 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 AEO67085.1 - 1.8e-16 59.6 0.0 3e-11 42.9 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 AEO67085.1 - 1.8e-15 57.1 4.5 1.8e-15 57.1 3.1 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AEO67085.1 - 2.4e-15 56.9 0.1 5.1e-12 46.0 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 AEO67085.1 - 9.2e-06 25.4 0.0 0.0017 18.0 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_16 PF13191.1 AEO67085.1 - 0.0004 20.4 0.4 0.0014 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Glyco_transf_21 PF13506.1 AEO67085.1 - 0.0023 17.2 0.0 0.0086 15.3 0.0 2.0 2 1 0 2 2 2 1 Glycosyl transferase family 21 AAA_22 PF13401.1 AEO67085.1 - 0.0035 17.4 0.3 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 AEO67085.1 - 0.033 12.8 0.0 0.062 11.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF1353 PF07087.6 AEO67085.1 - 0.055 12.9 0.0 0.4 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) MobB PF03205.9 AEO67085.1 - 0.067 12.8 0.1 0.29 10.8 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 AEO67085.1 - 0.15 10.6 0.0 0.96 8.0 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit SRPRB PF09439.5 AEO67085.1 - 0.23 10.6 0.3 1.1 8.4 0.3 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Chitin_synth_2 PF03142.10 AEO67086.1 - 6.7e-229 760.6 0.0 9e-229 760.2 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 AEO67086.1 - 2.2e-57 194.5 0.0 1.7e-56 191.6 0.0 2.2 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 AEO67086.1 - 9.3e-20 70.2 0.0 1.1e-13 50.7 0.0 2.6 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 AEO67086.1 - 3.1e-18 66.2 4.2 3.1e-18 66.2 2.9 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AEO67086.1 - 3.4e-16 59.7 0.0 1.6e-13 51.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DEK_C PF08766.6 AEO67086.1 - 4.7e-15 55.1 2.0 8.8e-14 51.0 1.8 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glyco_transf_21 PF13506.1 AEO67086.1 - 5.2e-07 29.1 0.0 1.9e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 AEO67086.1 - 0.00079 19.1 0.0 0.055 13.1 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 BCDHK_Adom3 PF10436.4 AEO67087.1 - 5e-45 152.9 0.0 7e-45 152.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 AEO67087.1 - 9e-17 60.7 0.0 1.1e-15 57.2 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.11 AEO67088.1 - 6.2e-13 49.1 0.2 7.3e-13 48.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 RVT_1 PF00078.22 AEO67090.1 - 0.12 11.7 0.7 0.12 11.7 0.5 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 AEO67091.1 - 0.12 11.7 0.7 0.12 11.7 0.5 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF663 PF04950.7 AEO67092.1 - 1.8e-90 302.9 0.0 1.8e-90 302.9 0.0 1.5 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 AEO67092.1 - 6.3e-28 96.1 0.0 4e-26 90.3 0.0 2.5 2 0 0 2 2 2 1 AARP2CN (NUC121) domain AAA_16 PF13191.1 AEO67092.1 - 9.8e-06 25.6 0.0 3.3e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AEO67092.1 - 9.8e-06 25.7 0.0 2.9e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 AEO67092.1 - 1.3e-05 24.6 0.0 0.0018 17.7 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA PF00004.24 AEO67092.1 - 0.00037 20.7 0.0 0.00085 19.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 AEO67092.1 - 0.00063 19.4 0.0 0.0013 18.3 0.0 1.6 1 1 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 AEO67092.1 - 0.00083 19.2 0.0 0.0023 17.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 AEO67092.1 - 0.00087 19.6 0.9 0.0032 17.7 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_17 PF13207.1 AEO67092.1 - 0.00096 19.9 0.0 0.00096 19.9 0.0 4.6 3 1 1 4 4 3 1 AAA domain AAA_10 PF12846.2 AEO67092.1 - 0.00099 18.6 0.0 0.0022 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 AEO67092.1 - 0.0014 18.3 1.0 0.0031 17.2 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain Miro PF08477.8 AEO67092.1 - 0.0016 18.9 0.0 0.005 17.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 AEO67092.1 - 0.0018 18.0 0.0 0.0046 16.6 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 AEO67092.1 - 0.0023 17.4 0.0 0.0086 15.5 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 AEO67092.1 - 0.0024 17.2 0.0 0.0064 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AEO67092.1 - 0.0028 17.5 0.0 0.0068 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AEO67092.1 - 0.0043 16.9 0.5 0.013 15.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 AEO67092.1 - 0.0046 17.2 0.0 0.0046 17.2 0.0 4.3 4 2 0 4 4 3 1 AAA domain NB-ARC PF00931.17 AEO67092.1 - 0.01 14.7 0.1 0.026 13.3 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.14 AEO67092.1 - 0.012 15.0 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 AEO67092.1 - 0.015 15.0 0.1 0.015 15.0 0.1 1.8 2 0 0 2 2 1 0 NTPase AAA_24 PF13479.1 AEO67092.1 - 0.016 14.7 0.1 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AEO67092.1 - 0.022 14.9 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 AEO67092.1 - 0.031 13.4 0.0 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_11 PF13086.1 AEO67092.1 - 0.34 10.4 3.7 2.7 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 AEO67092.1 - 1.1 8.7 6.0 2.3 7.6 0.0 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 AEO67092.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.6 3 1 0 3 3 2 0 AAA domain AAA_21 PF13304.1 AEO67092.1 - 1.4 8.8 0.0 1.4 8.8 0.0 3.1 4 0 0 4 4 3 0 AAA domain F-box-like PF12937.2 AEO67093.1 - 0.017 14.8 0.3 0.05 13.3 0.0 2.0 2 0 0 2 2 2 0 F-box-like APH PF01636.18 AEO67094.1 - 0.00022 21.0 0.0 0.00022 21.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_39 PF01229.12 AEO67095.1 - 0.0053 15.1 0.0 0.0072 14.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Yae1_N PF09811.4 AEO67096.1 - 0.13 11.8 1.1 1.7 8.2 0.6 2.2 2 0 0 2 2 2 0 Essential protein Yae1, N terminal Radical_SAM PF04055.16 AEO67098.1 - 3.9e-08 33.6 0.0 7.9e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.1 AEO67098.1 - 4.6e-05 23.5 0.0 8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 AEO67098.1 - 0.0015 18.5 0.1 0.0034 17.3 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF1681 PF07933.9 AEO67099.1 - 2.1e-51 173.6 0.0 2.7e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) IF-2B PF01008.12 AEO67100.1 - 1.8e-35 122.3 0.0 2.4e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family P22_CoatProtein PF11651.3 AEO67100.1 - 0.012 14.1 0.2 0.019 13.5 0.1 1.2 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 Ribosomal_S18 PF01084.15 AEO67100.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S18 4_1_CTD PF05902.8 AEO67100.1 - 0.032 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) GARS_N PF02844.10 AEO67100.1 - 0.099 13.1 0.1 1 9.8 0.0 2.5 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, N domain Methyltransf_33 PF10017.4 AEO67101.1 - 1e-30 106.2 0.2 2.5e-30 104.9 0.0 1.8 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent DinB_2 PF12867.2 AEO67101.1 - 1.7e-08 34.8 0.4 4.6e-08 33.4 0.3 1.8 1 0 0 1 1 1 1 DinB superfamily FGE-sulfatase PF03781.11 AEO67101.1 - 0.00019 20.8 0.0 0.00098 18.5 0.0 2.0 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 GFA PF04828.9 AEO67103.1 - 3.4e-18 65.3 3.2 7.7e-09 35.3 0.0 2.8 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 AEO67103.1 - 0.03 14.1 1.7 2.1 8.2 0.0 2.9 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Rsm1 PF08600.5 AEO67103.1 - 0.082 12.7 1.7 1.9 8.3 0.1 2.5 2 1 0 2 2 2 0 Rsm1-like zf-CSL PF05207.8 AEO67103.1 - 0.17 11.4 7.1 2.3 7.8 0.5 2.8 3 0 0 3 3 3 0 CSL zinc finger zf-ribbon_3 PF13248.1 AEO67103.1 - 5.9 6.2 10.6 2.6 7.3 0.0 4.1 4 0 0 4 4 4 0 zinc-ribbon domain PfkB PF00294.19 AEO67104.1 - 1.6e-17 63.6 0.8 4.6e-08 32.5 0.5 2.0 2 0 0 2 2 2 2 pfkB family carbohydrate kinase eIF3_subunit PF08597.5 AEO67106.1 - 3.3e-69 233.1 23.6 3.7e-69 233.0 16.4 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PRP4 PF08799.6 AEO67106.1 - 0.73 9.1 4.7 1.5 8.1 3.3 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Spore_coat_CotO PF14153.1 AEO67106.1 - 4 6.8 17.7 0.2 11.0 7.4 2.1 2 0 0 2 2 2 0 Spore coat protein CotO DDHD PF02862.12 AEO67106.1 - 4.7 6.9 16.2 3.8 7.2 0.1 2.3 2 0 0 2 2 2 0 DDHD domain MDM31_MDM32 PF08118.6 AEO67107.1 - 3.3e-185 616.3 0.2 8.4e-138 459.9 0.0 2.0 2 0 0 2 2 2 2 Yeast mitochondrial distribution and morphology (MDM) proteins DUF3825 PF12873.2 AEO67107.1 - 0.0064 15.6 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) TraH_2 PF06871.6 AEO67107.1 - 0.0092 15.4 0.1 0.023 14.1 0.1 1.6 1 0 0 1 1 1 1 TraH_2 Mito_fiss_reg PF05308.6 AEO67107.1 - 0.89 8.8 6.2 0.18 11.1 0.6 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator KH_1 PF00013.24 AEO67108.1 - 3e-05 23.5 1.1 6e-05 22.6 0.4 1.7 2 0 0 2 2 2 1 KH domain Rad60-SLD PF11976.3 AEO67109.1 - 5.9e-13 48.2 0.0 5.1e-12 45.3 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like RVT_1 PF00078.22 AEO67110.1 - 0.00063 19.1 0.2 0.00098 18.5 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) G-gamma PF00631.17 AEO67110.1 - 0.15 11.8 0.1 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 GGL domain Pox_Ag35 PF03286.9 AEO67111.1 - 0.0047 16.4 8.7 0.0068 15.9 6.0 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein PBP_sp32 PF07222.7 AEO67111.1 - 0.056 12.6 4.0 0.074 12.2 2.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF3246 PF11596.3 AEO67111.1 - 0.058 12.6 0.3 0.068 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Glypican PF01153.14 AEO67111.1 - 0.068 11.7 0.7 0.082 11.5 0.5 1.1 1 0 0 1 1 1 0 Glypican Na_trans_assoc PF06512.8 AEO67111.1 - 0.09 12.7 3.1 0.1 12.5 2.2 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated PBP1_TM PF14812.1 AEO67111.1 - 0.1 12.9 22.6 0.094 13.0 3.3 2.3 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 AEO67111.1 - 0.16 9.8 13.4 0.19 9.6 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 AEO67111.1 - 0.24 10.3 12.9 0.32 9.9 8.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TFIIF_alpha PF05793.7 AEO67111.1 - 0.29 9.4 17.6 0.37 9.1 12.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PGA2 PF07543.7 AEO67111.1 - 0.45 10.3 12.0 0.75 9.5 8.3 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF2201_N PF13203.1 AEO67111.1 - 0.83 8.7 6.2 1.2 8.2 4.3 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain Tom22 PF04281.8 AEO67111.1 - 0.91 9.0 6.6 0.28 10.6 0.7 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Daxx PF03344.10 AEO67111.1 - 0.94 7.8 10.1 1.3 7.3 7.0 1.3 1 0 0 1 1 1 0 Daxx Family AF1Q PF15017.1 AEO67111.1 - 1 9.3 8.6 9.5 6.2 0.1 2.2 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator RNase_H2_suC PF08615.6 AEO67111.1 - 1.1 9.0 5.0 26 4.6 3.5 2.0 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) eIF3_subunit PF08597.5 AEO67111.1 - 1.7 8.1 19.9 2.4 7.6 13.8 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1510 PF07423.6 AEO67111.1 - 2.1 7.6 12.8 2.6 7.3 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2151 PF10221.4 AEO67111.1 - 3.5 5.6 5.9 3.9 5.5 4.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator ANAPC15 PF15243.1 AEO67111.1 - 4.4 7.4 15.1 5.7 7.0 5.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 eIF-3c_N PF05470.7 AEO67111.1 - 5.1 5.0 9.1 6.1 4.8 6.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus adh_short PF00106.20 AEO67112.1 - 2.3e-21 76.4 5.9 4e-21 75.6 4.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO67112.1 - 6e-17 62.2 0.1 8.7e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO67112.1 - 8.5e-09 35.3 4.0 2.9e-08 33.5 2.8 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO67112.1 - 0.00025 20.5 0.4 0.0036 16.7 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 AEO67112.1 - 0.0051 17.2 0.6 0.012 16.0 0.4 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 AEO67112.1 - 0.043 12.7 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 AEO67113.1 - 5.6e-32 110.8 31.0 5.6e-32 110.8 21.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO67113.1 - 0.0009 17.9 5.7 0.0009 17.9 4.0 4.3 4 1 1 5 5 5 3 Sugar (and other) transporter CFEM PF05730.6 AEO67114.1 - 4.5e-11 42.3 10.3 4.5e-11 42.3 7.1 1.5 2 0 0 2 2 2 1 CFEM domain HET PF06985.6 AEO67116.1 - 1.9e-26 92.8 0.0 3.2e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glycos_transf_2 PF00535.21 AEO67117.1 - 4.6e-34 117.5 0.0 5.5e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AEO67117.1 - 1e-13 51.6 0.0 2e-13 50.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 AEO67117.1 - 2.8e-08 33.2 0.0 3.6e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 AEO67117.1 - 1.3e-05 24.6 0.0 1.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 AEO67117.1 - 0.017 15.4 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF221 PF02714.10 AEO67121.1 - 1.9e-96 322.7 19.5 2.8e-96 322.1 13.5 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AEO67121.1 - 3.9e-39 133.7 1.8 1.4e-38 131.9 1.2 2.0 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 AEO67121.1 - 2.4e-15 56.8 0.2 4.4e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) TMA7 PF09072.5 AEO67122.1 - 2.2e-25 88.8 19.4 2.4e-25 88.7 13.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 DUF3486 PF11985.3 AEO67122.1 - 0.074 13.1 2.7 0.072 13.1 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) Pkinase PF00069.20 AEO67123.1 - 3.5e-52 177.1 0.0 4.6e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO67123.1 - 4.5e-22 78.3 0.0 1.2e-21 76.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 AEO67123.1 - 0.042 12.6 0.0 0.062 12.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 AEO67123.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Glyco_transf_25 PF01755.12 AEO67124.1 - 6.2e-16 58.6 0.0 2.4e-11 43.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Pkinase PF00069.20 AEO67126.1 - 3.1e-59 200.2 0.0 4.1e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO67126.1 - 2.1e-31 108.9 0.0 3e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO67126.1 - 6.7e-06 25.2 0.0 1.6e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AEO67126.1 - 0.003 16.6 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO67126.1 - 0.02 14.6 0.0 0.02 14.6 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family UL11 PF11094.3 AEO67126.1 - 0.037 13.8 0.0 0.095 12.5 0.0 1.7 1 0 0 1 1 1 0 Membrane-associated tegument protein YrbL-PhoP_reg PF10707.4 AEO67126.1 - 0.064 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 AEO67126.1 - 0.07 11.9 0.3 0.11 11.2 0.0 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase AAA_19 PF13245.1 AEO67127.1 - 0.0036 17.0 0.4 2.8 7.7 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain BLOC1_2 PF10046.4 AEO67127.1 - 0.032 14.3 3.1 2.1 8.5 0.1 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WEMBL PF05701.6 AEO67127.1 - 0.22 9.9 2.5 6.1 5.1 0.1 2.0 2 0 0 2 2 2 0 Weak chloroplast movement under blue light HlyIII PF03006.15 AEO67128.1 - 4e-56 189.9 14.3 4.9e-56 189.6 9.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4231 PF14015.1 AEO67128.1 - 1.8 8.5 4.8 18 5.3 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) WD40 PF00400.27 AEO67129.1 - 0.0048 16.7 12.3 1.7 8.6 0.4 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat SDA1 PF05285.7 AEO67129.1 - 0.29 10.3 13.1 1.1 8.4 1.2 2.1 2 0 0 2 2 2 0 SDA1 Cornifin PF02389.10 AEO67131.1 - 0.032 14.0 2.1 0.062 13.0 1.5 1.4 1 1 0 1 1 1 0 Cornifin (SPRR) family FAD_binding_3 PF01494.14 AEO67132.1 - 3.3e-29 102.0 0.0 1.3e-28 100.0 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO67132.1 - 2.6e-06 26.5 0.0 0.022 13.6 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 AEO67132.1 - 6.9e-06 25.3 0.0 0.013 14.5 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 AEO67132.1 - 0.00058 19.9 0.0 0.0013 18.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO67132.1 - 0.0017 18.3 0.0 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain EF1G PF00647.14 AEO67132.1 - 0.002 17.7 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain Lycopene_cycl PF05834.7 AEO67132.1 - 0.036 12.9 0.0 0.41 9.5 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 AEO67132.1 - 0.068 12.0 0.2 0.18 10.5 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain adh_short PF00106.20 AEO67133.1 - 8.1e-07 29.1 0.1 1.1e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 AEO67133.1 - 0.036 14.0 0.2 0.051 13.5 0.2 1.4 1 0 0 1 1 1 0 NADH(P)-binding F420_oxidored PF03807.12 AEO67133.1 - 0.095 13.1 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HK97-gp10_like PF04883.7 AEO67134.1 - 0.12 13.3 0.1 0.21 12.5 0.1 1.4 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component MreB_Mbl PF06723.8 AEO67134.1 - 0.16 10.5 0.0 0.18 10.3 0.0 1.0 1 0 0 1 1 1 0 MreB/Mbl protein p47_phox_C PF08944.6 AEO67135.1 - 1.7 8.9 5.0 5 7.4 3.4 1.9 1 1 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain CFEM PF05730.6 AEO67136.1 - 8.2e-13 47.9 11.9 1.1e-12 47.5 8.2 1.1 1 0 0 1 1 1 1 CFEM domain Clr5 PF14420.1 AEO67137.1 - 3.1e-08 33.3 0.4 9.2e-08 31.8 0.0 2.1 3 0 0 3 3 3 1 Clr5 domain TauD PF02668.11 AEO67138.1 - 8e-54 183.0 0.8 9.7e-54 182.7 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_7 PF00840.15 AEO67140.1 - 6.6e-143 476.1 10.4 8.1e-143 475.8 7.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Mucin PF01456.12 AEO67142.1 - 0.061 13.0 21.3 0.1 12.3 14.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Antimicrobial_4 PF08024.6 AEO67143.1 - 3e-06 26.9 4.8 0.025 14.3 0.3 2.2 2 0 0 2 2 2 2 Ant antimicrobial peptide Antimicrobial15 PF08110.7 AEO67143.1 - 0.064 13.2 6.5 3.1 7.9 0.5 2.5 2 0 0 2 2 2 0 Ocellatin family Peptidase_S41 PF03572.13 AEO67143.1 - 0.12 11.8 0.1 1.4 8.3 0.1 2.0 1 1 0 1 1 1 0 Peptidase family S41 Homez PF11569.3 AEO67143.1 - 0.43 9.6 2.0 6 6.0 0.0 2.8 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez Radical_SAM PF04055.16 AEO67144.1 - 1.8e-12 47.7 0.0 3.4e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 AEO67144.1 - 5.8e-08 32.7 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 AEO67144.1 - 1.5e-07 31.6 0.0 2.5e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain ADK PF00406.17 AEO67145.1 - 1.6e-27 96.2 0.0 2.1e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 AEO67145.1 - 9.8e-11 41.7 0.0 1.3e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO67145.1 - 2.2e-09 38.1 0.0 2.7e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO67145.1 - 6.4e-08 32.9 0.0 9.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 AEO67145.1 - 0.0024 17.2 0.0 0.73 9.1 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase SKI PF01202.17 AEO67145.1 - 0.025 14.4 0.0 0.055 13.3 0.0 1.5 2 0 0 2 2 2 0 Shikimate kinase Zeta_toxin PF06414.7 AEO67145.1 - 0.039 13.0 0.0 0.1 11.6 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin AAA PF00004.24 AEO67145.1 - 0.067 13.3 0.0 0.082 13.1 0.0 1.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.1 AEO67145.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_28 PF13521.1 AEO67145.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain CYTH PF01928.16 AEO67146.1 - 8.4e-16 58.1 0.3 1.2e-15 57.6 0.2 1.2 1 0 0 1 1 1 1 CYTH domain NAD_binding_1 PF00175.16 AEO67148.1 - 3.3e-27 95.2 0.0 4.6e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AEO67148.1 - 3.3e-14 52.7 0.0 5.7e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AEO67148.1 - 9.8e-09 35.3 0.0 0.00038 20.3 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NMT1_2 PF13379.1 AEO67148.1 - 0.026 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family DEAD PF00270.24 AEO67149.1 - 6.6e-41 139.6 0.1 1.1e-40 138.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO67149.1 - 9e-16 57.5 0.0 1.9e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 AEO67149.1 - 7.9e-14 50.9 0.0 1.6e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 AEO67149.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PLRV_ORF5 PF01690.12 AEO67150.1 - 1.1 8.3 16.0 1.4 7.9 11.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Ndc1_Nup PF09531.5 AEO67150.1 - 4 5.7 9.3 4.7 5.4 6.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CytochromB561_N PF09786.4 AEO67150.1 - 4.2 5.7 12.9 5.2 5.3 8.9 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal PLDc PF00614.17 AEO67151.1 - 2.6e-15 55.6 5.2 6.5e-08 32.1 0.0 2.8 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.1 AEO67151.1 - 8.2e-11 41.7 0.0 4e-05 23.3 0.0 3.7 3 0 0 3 3 3 3 PLD-like domain GLTP PF08718.6 AEO67152.1 - 7.4e-47 159.1 0.2 1.9e-46 157.8 0.0 1.6 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) Ank_2 PF12796.2 AEO67153.1 - 3.6e-57 190.6 14.2 4.4e-14 52.5 1.6 8.7 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 AEO67153.1 - 3.8e-51 168.4 29.0 9.9e-10 37.7 0.1 13.9 13 1 0 13 13 13 10 Ankyrin repeat Ank_4 PF13637.1 AEO67153.1 - 3.4e-41 138.9 18.7 2.8e-06 27.6 0.0 9.8 8 1 1 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO67153.1 - 4.6e-41 134.7 24.6 1.6e-07 30.8 0.1 14.4 15 0 0 15 15 15 8 Ankyrin repeat Ank_5 PF13857.1 AEO67153.1 - 3e-29 100.3 27.4 3.6e-07 30.2 0.0 9.9 9 2 2 11 11 11 5 Ankyrin repeats (many copies) F-box-like PF12937.2 AEO67153.1 - 0.00057 19.5 0.2 0.0015 18.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO67153.1 - 0.001 18.6 0.3 0.0022 17.5 0.2 1.6 1 0 0 1 1 1 1 F-box domain Fungal_trans PF04082.13 AEO67154.1 - 5.1e-16 58.3 0.0 7.7e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO67154.1 - 4e-07 29.8 11.5 7.6e-07 28.9 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 AEO67155.1 - 7e-32 110.4 51.6 7e-32 110.4 35.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO67155.1 - 5e-06 25.3 13.6 5e-06 25.3 9.4 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter peroxidase PF00141.18 AEO67156.1 - 5.2e-90 300.9 0.0 9.3e-49 165.9 0.0 2.3 2 0 0 2 2 2 2 Peroxidase EthD PF07110.6 AEO67156.1 - 0.012 16.5 0.1 0.038 14.9 0.0 1.9 2 0 0 2 2 2 0 EthD domain MFS_1 PF07690.11 AEO67157.1 - 1.6e-25 89.5 30.7 2e-25 89.2 21.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CsbD PF05532.7 AEO67158.1 - 1.3e-10 40.8 1.7 3e-06 26.7 0.1 2.1 2 0 0 2 2 2 2 CsbD-like BNR_2 PF13088.1 AEO67159.1 - 0.00058 19.2 0.1 0.0074 15.6 0.0 2.2 1 1 1 2 2 2 2 BNR repeat-like domain Collagen PF01391.13 AEO67159.1 - 0.021 14.3 8.8 0.021 14.3 6.1 1.9 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Glyco_hydro_12 PF01670.11 AEO67160.1 - 5.1e-43 146.5 2.2 8.7e-43 145.7 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 APH PF01636.18 AEO67161.1 - 4.6e-19 69.1 0.1 8.2e-19 68.2 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 AEO67161.1 - 0.062 12.2 0.0 0.092 11.6 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase ABC_tran PF00005.22 AEO67162.1 - 8.4e-50 168.6 0.2 4.4e-24 85.3 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AEO67162.1 - 3.6e-16 59.9 0.4 0.00082 19.4 0.0 4.3 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 AEO67162.1 - 1e-15 57.5 0.2 9.5e-06 24.9 0.0 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AEO67162.1 - 3e-10 39.4 0.0 0.00098 18.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 AEO67162.1 - 9e-09 35.9 8.7 0.00029 21.2 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_17 PF13207.1 AEO67162.1 - 3.3e-08 34.3 0.0 0.0059 17.4 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 AEO67162.1 - 4e-08 33.4 0.0 0.00079 19.5 0.0 3.4 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 AEO67162.1 - 4.1e-08 32.5 0.1 0.00045 19.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 AEO67162.1 - 3.6e-07 30.1 0.0 0.0039 17.1 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 AEO67162.1 - 7.2e-07 29.3 0.1 0.026 14.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 AEO67162.1 - 1.6e-06 28.0 0.0 0.098 12.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 AEO67162.1 - 1.9e-06 27.2 1.4 0.13 11.3 0.0 4.5 3 2 1 4 4 4 1 AAA ATPase domain AAA_10 PF12846.2 AEO67162.1 - 2.3e-06 27.2 0.1 0.26 10.6 0.0 3.9 4 1 0 4 4 4 2 AAA-like domain Miro PF08477.8 AEO67162.1 - 2.4e-06 28.0 0.0 0.014 15.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 AEO67162.1 - 2.7e-06 27.3 0.2 0.00061 19.6 0.0 3.0 3 0 0 3 3 2 1 Dynamin family Adaptin_N PF01602.15 AEO67162.1 - 5.7e-06 24.9 0.4 1e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 Adaptin N terminal region AAA_18 PF13238.1 AEO67162.1 - 6.6e-06 26.4 0.3 0.12 12.6 0.0 3.6 3 0 0 3 3 2 2 AAA domain ArgK PF03308.11 AEO67162.1 - 1.2e-05 24.2 0.4 0.12 11.1 0.0 2.9 3 0 0 3 3 2 2 ArgK protein AAA PF00004.24 AEO67162.1 - 1.8e-05 24.9 0.0 0.49 10.6 0.0 4.3 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 AEO67162.1 - 1.9e-05 24.4 0.0 0.025 14.5 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 AEO67162.1 - 2.1e-05 24.2 0.0 0.24 11.0 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B HEAT_2 PF13646.1 AEO67162.1 - 4.3e-05 23.7 4.7 0.065 13.5 3.8 3.3 1 1 1 2 2 2 1 HEAT repeats PduV-EutP PF10662.4 AEO67162.1 - 6.9e-05 22.3 0.1 0.087 12.3 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 AEO67162.1 - 7.6e-05 22.8 0.0 0.62 10.2 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_16 PF13191.1 AEO67162.1 - 0.00011 22.2 0.5 0.72 9.8 0.0 4.1 5 0 0 5 5 4 1 AAA ATPase domain NACHT PF05729.7 AEO67162.1 - 0.0002 21.0 0.0 0.098 12.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 AEO67162.1 - 0.00022 20.9 0.0 0.75 9.4 0.0 2.9 2 0 0 2 2 2 2 Archaeal ATPase AAA_14 PF13173.1 AEO67162.1 - 0.00031 20.6 0.0 1.7 8.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain HEAT PF02985.17 AEO67162.1 - 0.00039 20.2 0.8 1 9.6 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat cobW PF02492.14 AEO67162.1 - 0.0012 18.3 0.2 1.7 8.0 0.0 3.4 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain ParcG PF10274.4 AEO67162.1 - 0.0015 18.4 1.3 2 8.2 0.1 3.2 1 1 2 3 3 3 1 Parkin co-regulated protein ATP-synt_ab PF00006.20 AEO67162.1 - 0.0017 17.9 0.1 1.6 8.1 0.0 2.7 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 AEO67162.1 - 0.0032 17.0 0.2 6.2 6.3 0.0 3.6 4 0 0 4 4 4 0 AAA domain Septin PF00735.13 AEO67162.1 - 0.0074 15.3 0.5 1.1 8.2 0.0 2.9 3 0 0 3 3 3 1 Septin AAA_25 PF13481.1 AEO67162.1 - 0.008 15.5 0.0 7.5 5.8 0.0 3.2 3 0 0 3 3 2 0 AAA domain MutS_V PF00488.16 AEO67162.1 - 0.0089 15.4 0.2 0.72 9.2 0.0 2.4 2 0 0 2 2 2 1 MutS domain V ATP_bind_1 PF03029.12 AEO67162.1 - 0.012 15.1 0.1 7.2 6.0 0.0 2.9 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein T2SE PF00437.15 AEO67162.1 - 0.019 13.8 0.1 1.9 7.2 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Rad17 PF03215.10 AEO67162.1 - 0.021 13.5 0.0 1.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein FtsK_SpoIIIE PF01580.13 AEO67162.1 - 0.026 13.9 0.1 3.9 6.8 0.0 2.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Cnd1 PF12717.2 AEO67162.1 - 0.03 14.1 0.0 0.42 10.4 0.0 2.5 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 AEO67162.1 - 0.037 14.5 7.9 2.9 8.4 0.2 5.2 5 1 1 6 6 3 0 HEAT-like repeat PRK PF00485.13 AEO67162.1 - 0.037 13.5 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.16 AEO67162.1 - 0.042 12.9 0.1 3.1 6.9 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_13 PF13166.1 AEO67162.1 - 0.084 11.3 14.6 1.4 7.3 0.0 4.7 4 1 0 5 5 5 0 AAA domain DUF87 PF01935.12 AEO67162.1 - 0.085 12.6 7.5 0.76 9.5 0.0 3.9 6 0 0 6 6 3 0 Domain of unknown function DUF87 V-ATPase_H_C PF11698.3 AEO67162.1 - 0.19 11.6 2.5 0.43 10.5 1.0 2.1 2 0 0 2 2 1 0 V-ATPase subunit H Macro PF01661.16 AEO67163.1 - 7.7e-38 129.0 0.0 1.1e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Macro domain tRNA-synt_1c PF00749.16 AEO67164.1 - 3.9e-99 331.2 0.0 5.9e-99 330.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 AEO67164.1 - 2.8e-34 118.2 0.0 9.5e-34 116.5 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain NARP1 PF12569.3 AEO67164.1 - 4 6.0 10.8 6.3 5.4 7.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Barttin PF15462.1 AEO67165.1 - 0.19 11.3 2.2 0.23 11.0 1.5 1.1 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Ubiq_cyt_C_chap PF03981.7 AEO67166.1 - 0.14 12.0 0.3 0.25 11.2 0.2 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone HAMP PF00672.20 AEO67167.1 - 0.031 14.4 2.5 1.4 9.2 0.1 2.6 2 0 0 2 2 2 0 HAMP domain Sporozoite_P67 PF05642.6 AEO67167.1 - 0.8 7.5 17.2 1.1 7.0 11.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4139 PF13598.1 AEO67168.1 - 9.4e-59 199.2 11.4 5.1e-57 193.5 1.6 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.1 AEO67168.1 - 9e-11 42.1 0.0 9e-11 42.1 0.0 4.5 4 1 0 4 4 4 2 N-terminal domain of unknown function (DUF4140) Sigma70_ner PF04546.8 AEO67168.1 - 0.0063 16.1 2.7 0.0063 16.1 1.9 2.3 2 0 0 2 2 2 1 Sigma-70, non-essential region PLRV_ORF5 PF01690.12 AEO67168.1 - 3.2 6.7 8.1 5.4 6.0 5.6 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Exo_endo_phos PF03372.18 AEO67169.1 - 1.2e-08 35.2 9.2 2.7e-08 34.0 6.4 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 AEO67169.1 - 0.0028 17.2 0.0 0.063 12.8 0.0 2.3 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase RNA_ligase PF09414.5 AEO67170.1 - 1.1e-11 44.8 0.0 2.5e-11 43.6 0.0 1.6 1 1 0 1 1 1 1 RNA ligase SNF5 PF04855.7 AEO67171.1 - 3e-83 279.0 0.0 4.5e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 AEO67171.1 - 5.5e-06 25.6 1.7 1.2e-05 24.4 1.2 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF2763 PF10961.3 AEO67171.1 - 2.2 8.7 6.6 4.6 7.6 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) Glyco_hydro_7 PF00840.15 AEO67172.1 - 2.6e-220 731.2 25.3 3.3e-220 730.8 17.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 AEO67172.1 - 6.2e-16 57.7 9.5 6.2e-16 57.7 6.6 4.8 4 1 0 4 4 4 1 Fungal cellulose binding domain Sporozoite_P67 PF05642.6 AEO67172.1 - 0.36 8.6 4.9 0.56 8.0 3.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NMT1 PF09084.6 AEO67173.1 - 1.2e-12 47.9 0.0 2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 AEO67173.1 - 3.6e-05 23.1 0.0 5.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.2 AEO67173.1 - 0.0026 17.1 0.1 0.0046 16.3 0.1 1.6 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Methyltransf_2 PF00891.13 AEO67174.1 - 2.4e-26 92.4 0.0 3.6e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase DUF433 PF04255.9 AEO67174.1 - 0.087 12.2 0.0 0.27 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Methyltransf_25 PF13649.1 AEO67174.1 - 0.097 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.13 AEO67175.1 - 1.8e-19 69.6 0.1 2.6e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO67175.1 - 6.6e-08 32.3 13.8 1.1e-07 31.6 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO67176.1 - 6.8e-16 57.9 0.0 1.1e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO67176.1 - 5.6e-07 29.3 10.3 9.7e-07 28.6 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.23 AEO67176.1 - 0.01 15.5 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain TPR_11 PF13414.1 AEO67177.1 - 0.0019 17.7 0.2 0.18 11.4 0.0 3.0 3 0 0 3 3 3 1 TPR repeat TPR_9 PF13371.1 AEO67177.1 - 0.013 15.3 0.0 0.013 15.3 0.0 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Lamp PF01299.12 AEO67177.1 - 0.16 11.0 0.1 0.34 10.0 0.0 1.5 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Cytochrom_B561 PF03188.11 AEO67178.1 - 1.2e-05 25.1 1.3 1.2e-05 25.1 0.9 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 GpcrRhopsn4 PF10192.4 AEO67178.1 - 0.009 15.2 0.2 0.013 14.6 0.2 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain EphA2_TM PF14575.1 AEO67178.1 - 0.022 15.1 0.0 0.16 12.4 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.3 AEO67178.1 - 0.057 13.9 2.3 0.091 13.3 0.3 2.1 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF3169 PF11368.3 AEO67178.1 - 0.15 11.2 0.2 4.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Cytochrom_B_N PF00033.14 AEO67178.1 - 0.36 10.1 14.1 0.14 11.4 6.5 2.5 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 AEO67178.1 - 0.47 9.8 10.6 0.51 9.7 5.1 2.3 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 AA_permease PF00324.16 AEO67178.1 - 0.69 8.1 7.5 0.041 12.2 0.3 1.9 1 1 1 2 2 2 0 Amino acid permease DUF3382 PF11862.3 AEO67178.1 - 0.91 9.4 6.2 0.73 9.7 2.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) DUF1049 PF06305.6 AEO67178.1 - 2.4 7.6 5.5 19 4.8 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) PepSY_TM_2 PF13703.1 AEO67178.1 - 6.4 7.0 11.2 0.53 10.4 3.1 2.6 2 1 1 3 3 3 0 PepSY-associated TM helix Cellulase PF00150.13 AEO67179.1 - 1.8e-53 181.5 0.0 2.1e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TOBE_3 PF12857.2 AEO67179.1 - 0.059 13.2 0.0 11 6.0 0.0 2.3 2 0 0 2 2 2 0 TOBE-like domain MFS_1 PF07690.11 AEO67180.1 - 1e-13 50.7 34.5 7.7e-11 41.3 18.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PPR_2 PF13041.1 AEO67182.1 - 2.3e-47 158.7 6.7 2.2e-09 37.1 0.0 15.1 11 3 7 18 18 18 11 PPR repeat family PPR PF01535.15 AEO67182.1 - 8.4e-26 88.1 26.8 0.00019 21.1 0.0 14.2 18 0 0 18 18 18 7 PPR repeat PPR_3 PF13812.1 AEO67182.1 - 3.1e-25 86.3 33.0 6.8e-05 22.8 0.0 16.3 17 1 1 18 18 18 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 AEO67182.1 - 8.1e-23 79.6 0.4 1.8e-08 33.6 0.0 9.1 10 0 0 10 10 10 5 PPR repeat RPM2 PF08579.6 AEO67182.1 - 1.8e-05 24.8 0.0 0.0013 18.8 0.0 3.8 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.2 AEO67182.1 - 0.00036 19.8 0.1 0.17 11.2 0.0 3.6 3 0 0 3 3 3 1 Mitochondrial ATPase expression TPR_7 PF13176.1 AEO67182.1 - 3.5 7.6 8.1 11 6.0 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.21 AEO67183.1 - 7.7e-15 54.7 2.3 8.5e-15 54.5 0.4 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AEO67183.1 - 7.1e-07 29.3 0.0 1.5e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Aldedh PF00171.17 AEO67185.1 - 5.8e-135 450.2 0.0 6.4e-135 450.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 AEO67185.1 - 1.8e-09 36.8 0.0 2.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 AEO67185.1 - 0.05 12.8 0.1 0.51 9.5 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) RRM_6 PF14259.1 AEO67186.1 - 9.4e-09 35.1 0.0 2.8e-08 33.6 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO67186.1 - 2.5e-08 33.4 0.2 6.1e-06 25.7 0.0 2.9 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO67186.1 - 0.0001 22.0 0.1 0.0015 18.3 0.1 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Colicin-DNase PF12639.2 AEO67186.1 - 0.082 13.1 0.3 1.5 9.0 0.0 2.9 2 1 2 4 4 4 0 DNase/tRNase domain of colicin-like bacteriocin NMD3 PF04981.8 AEO67188.1 - 3.9e-71 238.9 1.8 5.5e-71 238.4 1.3 1.2 1 0 0 1 1 1 1 NMD3 family DUF35_N PF12172.3 AEO67188.1 - 0.0089 15.9 1.4 0.25 11.3 0.1 2.7 2 0 0 2 2 2 1 Rubredoxin-like zinc ribbon domain (DUF35_N) TPR_11 PF13414.1 AEO67189.1 - 3.9e-12 45.6 6.8 1.1e-11 44.2 1.2 2.6 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 AEO67189.1 - 0.00022 21.0 0.8 0.00022 21.0 0.5 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 AEO67189.1 - 0.00062 19.2 5.2 0.72 9.5 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 AEO67189.1 - 0.019 14.8 12.0 0.26 11.3 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 AEO67189.1 - 0.028 14.2 0.7 0.32 10.9 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 AEO67189.1 - 0.1 12.7 0.9 0.22 11.7 0.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Phage_GPD PF05954.6 AEO67189.1 - 0.36 9.9 5.3 0.072 12.2 1.3 1.5 2 0 0 2 2 2 0 Phage late control gene D protein (GPD) HAD_2 PF13419.1 AEO67190.1 - 1.1e-13 51.7 0.0 4.4e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO67190.1 - 0.00017 21.2 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 AEO67190.1 - 0.00022 21.6 0.0 0.0095 16.3 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sporozoite_P67 PF05642.6 AEO67190.1 - 2.9 5.6 5.6 3.8 5.2 3.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen WD40 PF00400.27 AEO67191.1 - 6.7e-21 73.3 0.3 0.0013 18.4 0.0 6.3 6 1 0 6 6 6 5 WD domain, G-beta repeat TFIIA PF03153.8 AEO67191.1 - 7 6.4 10.8 10 5.9 7.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MBD_C PF14048.1 AEO67191.1 - 7.9 7.1 7.9 0.16 12.6 0.6 1.8 2 0 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 Fungal_trans_2 PF11951.3 AEO67192.1 - 3.4e-08 32.4 0.0 4.3e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO67192.1 - 1.6e-06 27.9 14.1 2e-06 27.6 7.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2486 PF10667.4 AEO67192.1 - 2.1 8.8 5.1 2.4 8.6 2.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2486) Acyltransferase PF01553.16 AEO67193.1 - 2.9e-19 68.8 0.0 6.9e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase UPF0086 PF01868.11 AEO67194.1 - 7.9e-24 83.1 0.0 1.3e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Milton PF12448.3 AEO67194.1 - 0.13 12.3 2.6 0.24 11.6 1.8 1.4 1 0 0 1 1 1 0 Kinesin associated protein Pantoate_ligase PF02569.10 AEO67195.1 - 3.2e-82 275.4 0.0 5.8e-82 274.5 0.0 1.4 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Peptidase_S10 PF00450.17 AEO67196.1 - 2.2e-56 191.8 0.0 2.8e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF1772 PF08592.6 AEO67198.1 - 7.4e-05 22.4 4.0 0.045 13.4 2.2 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF1772) PUA PF01472.15 AEO67199.1 - 6.6e-13 48.1 0.3 1.3e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 PUA domain Inhibitor_I78 PF11720.3 AEO67200.1 - 1.2e-11 44.1 0.0 1.4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 AEO67200.1 - 0.0022 18.0 0.0 0.0032 17.5 0.0 1.2 1 0 0 1 1 1 1 Potato inhibitor I family DUF1049 PF06305.6 AEO67201.1 - 0.15 11.5 0.4 0.39 10.2 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) NST1 PF13945.1 AEO67202.1 - 6.1e-62 209.0 4.8 6.1e-62 209.0 3.3 4.7 3 1 1 4 4 4 1 Salt tolerance down-regulator Ras PF00071.17 AEO67203.1 - 5.3e-49 165.7 0.0 6.1e-49 165.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO67203.1 - 2.1e-15 57.2 0.0 2.8e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO67203.1 - 4.7e-06 25.9 0.0 6.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_21 PF13304.1 AEO67203.1 - 0.033 14.1 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 AEO67203.1 - 0.041 13.0 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 AEO67203.1 - 0.045 13.2 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 AEO67203.1 - 0.059 12.5 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MRP-L28 PF09812.4 AEO67204.1 - 2.4e-10 40.4 0.4 3e-10 40.1 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 GATase_5 PF13507.1 AEO67205.1 - 1.4e-98 328.9 0.0 2e-98 328.3 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 AEO67205.1 - 2.1e-40 138.2 1.1 1.4e-21 77.0 0.0 2.6 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 AEO67205.1 - 1.7e-24 85.8 0.1 1e-23 83.3 0.0 2.4 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain TPR_11 PF13414.1 AEO67206.1 - 2e-18 65.7 12.1 1.8e-15 56.2 6.2 2.7 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 AEO67206.1 - 4e-15 54.6 8.4 6.2e-08 31.9 0.7 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 AEO67206.1 - 3.1e-13 48.5 12.1 3.4e-06 26.5 0.7 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 AEO67206.1 - 6.6e-08 33.0 16.1 2.2e-05 24.9 3.8 3.1 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 AEO67206.1 - 4.4e-07 29.5 5.9 0.0013 18.7 0.2 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AEO67206.1 - 1.5e-06 28.2 10.3 0.011 16.2 0.3 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 AEO67206.1 - 9e-06 25.1 2.0 0.013 15.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 AEO67206.1 - 4.2e-05 23.3 8.8 0.014 15.3 0.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 AEO67206.1 - 0.00022 21.4 5.0 0.00022 21.4 3.4 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 AEO67206.1 - 0.00089 18.8 9.1 0.35 10.7 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.12 AEO67206.1 - 0.002 18.4 3.2 0.66 10.2 0.4 2.6 1 1 1 2 2 2 2 Bacterial transcriptional activator domain XPC-binding PF09280.6 AEO67206.1 - 0.015 14.7 3.1 0.027 13.9 1.9 1.6 2 0 0 2 2 1 0 XPC-binding domain TPR_9 PF13371.1 AEO67206.1 - 0.018 14.8 4.9 0.018 14.8 1.7 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat U79_P34 PF03064.11 AEO67206.1 - 0.047 13.2 0.5 0.094 12.2 0.4 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TPR_10 PF13374.1 AEO67206.1 - 0.047 13.6 7.0 0.77 9.7 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO67206.1 - 0.28 11.7 11.2 1.5 9.4 0.2 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat RINGv PF12906.2 AEO67207.1 - 6.3e-05 22.9 5.9 0.0001 22.2 4.1 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 AEO67207.1 - 0.0002 21.1 6.1 0.0003 20.5 4.2 1.3 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 AEO67207.1 - 0.00071 19.4 4.5 0.0014 18.5 3.1 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 AEO67207.1 - 0.03 13.9 4.3 0.049 13.3 3.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CopD PF05425.8 AEO67207.1 - 0.03 14.5 4.3 1.3 9.3 0.8 2.7 2 0 0 2 2 2 0 Copper resistance protein D zf-RING_4 PF14570.1 AEO67207.1 - 0.13 11.8 4.5 0.25 10.9 3.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TPP_enzyme_N PF02776.13 AEO67208.1 - 2.4e-57 193.1 0.1 7.3e-57 191.5 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 AEO67208.1 - 1.1e-49 167.9 1.1 2.1e-48 163.7 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 AEO67208.1 - 5.3e-36 123.3 2.5 1.5e-35 121.8 0.3 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Reg_prop PF07494.6 AEO67210.1 - 0.12 12.4 0.1 9.9 6.5 0.1 2.5 2 0 0 2 2 2 0 Two component regulator propeller DUF3659 PF12396.3 AEO67212.1 - 2e-16 59.3 0.4 8.8e-12 44.5 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) Borrelia_P83 PF05262.6 AEO67212.1 - 0.022 13.0 0.6 0.027 12.7 0.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Scm3 PF10384.4 AEO67212.1 - 0.1 12.1 0.0 0.3 10.5 0.0 1.8 1 0 0 1 1 1 0 Centromere protein Scm3 DUF3987 PF13148.1 AEO67212.1 - 0.85 8.1 10.0 1.3 7.5 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF3449 PF11931.3 AEO67212.1 - 1.8 8.0 5.5 2.9 7.3 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF3659 PF12396.3 AEO67213.1 - 3.3e-104 340.5 53.5 6.1e-23 80.2 1.4 5.9 6 0 0 6 6 6 5 Protein of unknown function (DUF3659) Trypan_PARP PF05887.6 AEO67213.1 - 0.022 14.5 1.1 0.022 14.5 0.8 3.5 4 0 0 4 4 4 0 Procyclic acidic repetitive protein (PARP) SNF2_N PF00176.18 AEO67215.1 - 1.9e-71 240.3 0.0 2.8e-71 239.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 AEO67215.1 - 1.3e-16 60.4 0.0 2.6e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 AEO67215.1 - 5.9e-11 42.0 0.0 1.7e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 AEO67215.1 - 1.7e-10 40.3 12.0 1.6e-09 37.2 6.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO67215.1 - 5.1e-10 39.0 11.5 5.1e-10 39.0 8.0 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO67215.1 - 5.7e-09 35.8 18.9 7e-09 35.5 9.5 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO67215.1 - 2.2e-08 33.5 14.2 2.2e-08 33.5 9.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO67215.1 - 2.5e-06 27.0 11.7 2.5e-06 27.0 8.1 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AEO67215.1 - 4.5e-06 26.4 10.9 9.9e-06 25.3 7.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 AEO67215.1 - 0.00081 19.4 9.9 0.0028 17.7 6.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 AEO67215.1 - 0.0014 18.3 5.6 0.0042 16.8 3.9 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 AEO67215.1 - 0.0027 17.4 10.0 0.0027 17.4 6.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-P11 PF03854.9 AEO67215.1 - 0.015 14.7 6.7 0.62 9.5 2.3 2.6 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.1 AEO67215.1 - 0.015 14.8 8.0 0.033 13.7 5.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 AEO67215.1 - 0.089 12.6 4.9 0.24 11.2 3.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-Apc11 PF12861.2 AEO67215.1 - 0.11 12.3 6.5 0.31 10.9 4.5 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 AEO67215.1 - 0.2 11.1 9.6 0.71 9.4 6.6 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Cpn10 PF00166.16 AEO67216.1 - 4.1e-28 97.1 0.0 4.6e-28 96.9 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase PF00069.20 AEO67217.1 - 2.5e-59 200.5 0.0 4.9e-59 199.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO67217.1 - 9.6e-22 77.2 0.0 1.8e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO67217.1 - 0.0039 16.9 0.1 0.0094 15.6 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ribosomal_L11_N PF03946.9 AEO67218.1 - 3.5e-26 90.4 0.2 6e-26 89.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 AEO67218.1 - 5.5e-25 87.3 1.2 1.5e-24 85.9 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Svf1 PF08622.5 AEO67219.1 - 3.7e-133 443.5 0.0 4.4e-133 443.2 0.0 1.1 1 0 0 1 1 1 1 Svf1-like Histone PF00125.19 AEO67220.1 - 2e-09 37.4 0.6 2.8e-09 36.9 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AEO67220.1 - 0.0023 17.9 0.5 0.004 17.1 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PCP_red PF08369.5 AEO67220.1 - 0.016 15.0 1.3 0.15 11.9 0.1 2.2 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Diphtheria_T PF02764.9 AEO67220.1 - 0.062 13.0 0.0 0.084 12.6 0.0 1.1 1 0 0 1 1 1 0 Diphtheria toxin, T domain DUF4095 PF13338.1 AEO67220.1 - 0.1 12.7 0.8 0.17 12.0 0.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4095) Acetyltransf_7 PF13508.1 AEO67221.1 - 0.02 15.0 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO67221.1 - 0.028 14.4 0.2 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Pho86 PF11124.3 AEO67221.1 - 0.053 12.4 0.0 0.068 12.1 0.0 1.1 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 DUF2955 PF11168.3 AEO67221.1 - 0.057 13.0 0.7 0.079 12.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) AOX PF01786.12 AEO67222.1 - 6.3e-89 296.8 0.0 7.6e-89 296.5 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase zf-H2C2_2 PF13465.1 AEO67223.1 - 3.2e-14 52.4 8.6 5.4e-08 32.7 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 AEO67223.1 - 1.8e-12 46.8 12.7 8.3e-06 25.8 1.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO67223.1 - 7.2e-11 41.6 12.6 4e-05 23.6 1.8 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO67223.1 - 1.2e-07 31.6 1.6 0.031 14.4 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO67223.1 - 7.4e-05 22.8 2.3 0.014 15.5 0.2 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 AEO67223.1 - 0.077 13.2 0.7 0.15 12.3 0.5 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.7 AEO67223.1 - 0.12 12.4 2.1 0.25 11.4 1.5 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.17 AEO67223.1 - 1 9.4 3.9 6.6 6.8 2.7 2.1 1 1 1 2 2 2 0 LIM domain zf-C2H2_6 PF13912.1 AEO67223.1 - 3.5 7.6 10.2 11 6.0 0.4 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger ADH_zinc_N PF00107.21 AEO67224.1 - 2.6e-12 46.4 0.0 1.6e-11 43.8 0.0 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO67224.1 - 5.5e-07 29.3 1.2 1.5e-06 27.9 0.6 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 AEO67227.1 - 2.2e-49 168.0 17.5 2.2e-49 168.0 12.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO67227.1 - 3.6e-09 35.7 9.7 3.6e-09 35.7 6.8 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter DUF4381 PF14316.1 AEO67227.1 - 3.2 7.8 5.9 22 5.1 0.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Syntaxin-18_N PF10496.4 AEO67228.1 - 5e-16 58.3 0.1 1.5e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus DAGK_cat PF00781.19 AEO67229.1 - 5.1e-28 97.1 0.0 8.5e-28 96.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Nop52 PF05997.7 AEO67230.1 - 3.1e-42 144.4 0.1 3.9e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.3 AEO67230.1 - 0.072 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Aminotran_1_2 PF00155.16 AEO67231.1 - 9.8e-84 281.3 0.0 1.1e-83 281.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II NARP1 PF12569.3 AEO67232.1 - 9.2e-193 641.6 23.2 3.2e-188 626.7 10.0 3.4 2 2 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 AEO67232.1 - 1.3e-25 89.4 35.8 3.5e-06 27.5 0.0 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 AEO67232.1 - 1.5e-22 79.0 33.1 1.7e-06 27.5 0.1 8.0 7 1 0 8 8 8 4 TPR repeat TPR_14 PF13428.1 AEO67232.1 - 9.6e-18 63.0 34.9 0.00022 21.5 0.6 11.2 8 3 4 12 12 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 AEO67232.1 - 1.4e-17 63.7 33.3 1.3e-05 25.4 0.1 7.3 6 2 2 8 8 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 AEO67232.1 - 1.9e-16 58.5 44.5 0.00055 19.6 0.1 11.7 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_9 PF13371.1 AEO67232.1 - 4e-13 49.0 20.5 0.00076 19.2 0.0 7.3 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 AEO67232.1 - 5.6e-13 47.9 19.8 0.0039 17.2 0.0 9.4 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_1 PF00515.23 AEO67232.1 - 9.1e-12 44.0 34.9 1.7e-05 24.1 0.1 10.1 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.1 AEO67232.1 - 2.9e-08 33.5 33.4 0.0027 17.5 0.2 8.7 7 3 1 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO67232.1 - 6.8e-08 31.7 19.4 0.0029 17.2 0.0 8.5 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_15 PF13429.1 AEO67232.1 - 2.4e-06 26.8 19.7 0.0023 17.0 3.4 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AEO67232.1 - 0.0012 18.7 9.0 1.8 8.5 0.1 5.4 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat PPTA PF01239.17 AEO67232.1 - 0.0059 15.9 0.2 1.7 8.1 0.0 3.6 3 0 0 3 3 3 1 Protein prenyltransferase alpha subunit repeat BTAD PF03704.12 AEO67232.1 - 0.011 15.9 0.6 0.011 15.9 0.4 3.4 2 1 1 3 3 2 0 Bacterial transcriptional activator domain TPR_7 PF13176.1 AEO67232.1 - 0.025 14.3 23.6 1.7 8.6 0.3 8.4 9 1 1 10 10 9 0 Tetratricopeptide repeat TPR_3 PF07720.7 AEO67232.1 - 0.031 14.0 4.5 0.5 10.2 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Mgr1 PF08602.5 AEO67232.1 - 0.16 10.9 1.0 0.33 9.8 0.3 1.8 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit TPR_10 PF13374.1 AEO67232.1 - 0.2 11.6 0.1 0.2 11.6 0.1 7.8 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO67232.1 - 1.1 9.8 37.6 0.2 12.1 0.2 9.3 11 0 0 11 11 9 0 Tetratricopeptide repeat TPR_4 PF07721.9 AEO67232.1 - 5.6 7.6 24.3 7.2 7.3 0.1 7.4 8 0 0 8 8 6 0 Tetratricopeptide repeat Cid2 PF09774.4 AEO67233.1 - 2.1e-49 167.5 0.0 2.5e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Zn_clus PF00172.13 AEO67234.1 - 8.8e-08 31.9 11.0 1.4e-07 31.3 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 AEO67235.1 - 3.2e-57 192.5 0.0 4.2e-57 192.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AEO67235.1 - 2.1e-20 72.5 0.0 2.8e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AEO67235.1 - 2e-06 27.7 0.1 3.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AEO67235.1 - 0.035 14.5 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 AEO67235.1 - 0.036 13.4 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 AEO67235.1 - 0.077 13.0 0.1 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AdoHcyase PF05221.12 AEO67236.1 - 1e-140 467.2 0.3 1.2e-140 467.0 0.2 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 AEO67236.1 - 1.1e-83 279.0 2.9 1.8e-83 278.2 2.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 AEO67236.1 - 1.3e-06 27.6 0.9 2e-06 27.0 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 AEO67236.1 - 0.0081 15.5 0.2 0.015 14.6 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TMEM107 PF14995.1 AEO67236.1 - 0.016 15.3 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein TrkA_N PF02254.13 AEO67236.1 - 0.018 15.0 0.1 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ig PF00047.20 AEO67236.1 - 0.019 15.0 0.0 2.7 8.1 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin domain ELFV_dehydrog PF00208.16 AEO67236.1 - 0.08 12.5 1.5 0.096 12.2 0.3 1.8 2 1 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase JAB PF01398.16 AEO67237.1 - 1.3e-07 31.3 0.2 2.9e-06 26.9 0.2 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Rad60-SLD PF11976.3 AEO67239.1 - 1.1e-07 31.4 0.4 1.2e-07 31.2 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like LAGLIDADG_1 PF00961.14 AEO67239.1 - 0.07 13.6 0.9 0.077 13.5 0.6 1.1 1 0 0 1 1 1 0 LAGLIDADG endonuclease DUF2460 PF09343.5 AEO67239.1 - 0.088 12.1 0.0 0.095 12.0 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) SRP9-21 PF05486.7 AEO67239.1 - 0.15 11.8 1.2 0.31 10.8 0.7 1.6 1 1 1 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) GalKase_gal_bdg PF10509.4 AEO67240.1 - 3e-20 71.2 0.0 7.2e-20 70.0 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 AEO67240.1 - 2e-13 50.1 2.2 8.2e-13 48.2 1.4 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AEO67240.1 - 7.5e-12 45.2 0.0 1.9e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r4_2 PF08281.7 AEO67240.1 - 0.031 13.7 0.0 0.076 12.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 TauD PF02668.11 AEO67241.1 - 6.3e-43 147.3 0.0 7.4e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Plasmod_MYXSPDY PF07981.6 AEO67241.1 - 0.14 11.8 1.3 0.31 10.7 0.9 1.6 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY MFS_1 PF07690.11 AEO67242.1 - 1.8e-16 59.8 13.0 2.2e-16 59.5 9.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CBM_2 PF00553.14 AEO67242.1 - 0.034 14.2 0.4 0.063 13.3 0.3 1.4 1 0 0 1 1 1 0 Cellulose binding domain DUF308 PF03729.8 AEO67242.1 - 1.2 9.2 16.0 0.12 12.3 4.6 3.3 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Rib_5-P_isom_A PF06026.9 AEO67243.1 - 4.8e-41 139.9 0.0 1.7e-38 131.6 0.0 2.1 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 AEO67243.1 - 0.048 13.3 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain Fungal_trans PF04082.13 AEO67244.1 - 1.6e-11 43.5 0.0 2.8e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO67244.1 - 8.4e-06 25.5 7.5 1.5e-05 24.7 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO67244.1 - 0.00035 19.3 0.7 0.0016 17.1 0.5 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain PKD_channel PF08016.7 AEO67245.1 - 4.4e-05 22.0 17.1 0.0023 16.4 6.5 2.2 2 0 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.26 AEO67245.1 - 0.0004 19.7 17.6 0.04 13.1 12.2 2.3 1 1 0 1 1 1 1 Ion transport protein Sec2p PF06428.6 AEO67245.1 - 0.072 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF843 PF05814.6 AEO67245.1 - 1.3 8.8 5.6 2.1 8.2 0.2 2.8 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) AAA PF00004.24 AEO67246.1 - 4.9e-15 55.9 0.0 1.2e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 AEO67246.1 - 0.00013 21.6 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 AEO67246.1 - 0.0088 15.7 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 AEO67246.1 - 0.011 16.5 0.6 0.047 14.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 AEO67246.1 - 0.03 14.4 0.8 0.03 14.4 0.6 2.8 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 AEO67246.1 - 0.08 12.9 3.6 0.14 12.0 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain Methyltransf_10 PF05971.7 AEO67248.1 - 3.5e-64 216.8 0.0 4.6e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 AEO67248.1 - 7.4e-06 25.9 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO67248.1 - 2.5e-05 23.7 0.0 4.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 AEO67248.1 - 0.00019 21.9 0.0 0.00041 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AEO67248.1 - 0.0072 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 AEO67248.1 - 0.076 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_31 PF13847.1 AEO67248.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 AEO67248.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 XAP5 PF04921.9 AEO67249.1 - 2.6e-82 275.9 0.0 4.5e-82 275.2 0.0 1.4 2 0 0 2 2 2 1 XAP5, circadian clock regulator NAD_binding_10 PF13460.1 AEO67250.1 - 2.8e-07 30.7 0.0 7.1e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO67250.1 - 0.00011 21.7 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO67250.1 - 0.00075 18.4 0.1 0.002 17.1 0.1 1.8 1 1 2 3 3 3 1 Male sterility protein DapB_N PF01113.15 AEO67250.1 - 0.019 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 AEO67250.1 - 0.057 13.3 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 AEO67250.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 AEO67250.1 - 0.18 10.5 0.0 0.32 9.6 0.1 1.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1423 PF07227.6 AEO67251.1 - 0.14 10.7 5.1 0.21 10.1 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) V_ATPase_I PF01496.14 AEO67251.1 - 2.4 5.9 4.7 3.2 5.4 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dynamin_N PF00350.18 AEO67252.1 - 1e-32 113.2 0.0 1.9e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 AEO67252.1 - 1.5e-16 60.0 0.1 5.6e-14 51.6 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 AEO67252.1 - 4.5e-05 23.3 0.0 0.00023 21.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 AEO67252.1 - 0.00033 20.4 0.7 0.028 14.2 0.0 3.6 4 0 0 4 4 4 1 Dynamin GTPase effector domain Miro PF08477.8 AEO67252.1 - 0.001 19.5 0.0 0.0066 16.9 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein AAA_21 PF13304.1 AEO67252.1 - 0.023 14.6 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AEO67252.1 - 0.12 12.6 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 AEO67252.1 - 0.13 11.7 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ADH_zinc_N_2 PF13602.1 AEO67253.1 - 1.4e-23 84.1 0.1 3e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 AEO67253.1 - 3.3e-15 55.7 0.0 8.2e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO67253.1 - 1.3e-07 31.3 0.4 0.00036 20.2 0.0 3.7 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Esterase_phd PF10503.4 AEO67255.1 - 2.7e-24 85.6 0.1 3.6e-24 85.2 0.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 AEO67255.1 - 2.4e-09 36.7 0.8 3.8e-09 36.0 0.6 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO67255.1 - 2.7e-07 30.4 0.1 3.6e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 AEO67255.1 - 1.5e-05 23.9 1.8 3.3e-05 22.8 0.2 1.9 2 0 0 2 2 2 1 Carboxylesterase family Esterase PF00756.15 AEO67255.1 - 5.5e-05 22.7 0.6 9.4e-05 21.9 0.4 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 AEO67255.1 - 0.0003 20.7 0.0 0.00044 20.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO67255.1 - 0.0027 17.3 0.0 0.0044 16.6 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 AEO67255.1 - 0.0065 16.0 0.0 0.0085 15.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Eno-Rase_NADH_b PF12242.3 AEO67255.1 - 0.039 13.7 0.1 0.071 12.9 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase BAAT_C PF08840.6 AEO67255.1 - 0.057 13.1 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal WLM PF08325.5 AEO67256.1 - 0.049 13.5 3.4 0.071 12.9 2.3 1.3 1 0 0 1 1 1 0 WLM domain U6-snRNA_bdg PF10596.4 AEO67256.1 - 0.12 11.7 0.8 0.19 11.1 0.5 1.6 1 1 0 1 1 1 0 U6-snRNA interacting domain of PrP8 DUF4615 PF15393.1 AEO67256.1 - 0.29 11.3 8.1 0.7 10.1 5.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) Amidase PF01425.16 AEO67256.1 - 0.37 9.5 5.4 0.43 9.3 3.7 1.1 1 0 0 1 1 1 0 Amidase ARGLU PF15346.1 AEO67256.1 - 0.66 9.7 31.0 0.079 12.7 17.4 1.9 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 DUF948 PF06103.6 AEO67256.1 - 0.86 9.4 2.8 18 5.2 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SprA-related PF12118.3 AEO67256.1 - 1.6 7.9 14.2 1.7 7.8 9.8 1.1 1 0 0 1 1 1 0 SprA-related family RR_TM4-6 PF06459.7 AEO67256.1 - 2.9 7.7 10.9 3.4 7.4 7.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S46 PF10459.4 AEO67256.1 - 4.5 5.5 12.4 5.3 5.3 8.6 1.0 1 0 0 1 1 1 0 Peptidase S46 DDHD PF02862.12 AEO67256.1 - 8.4 6.1 7.9 9.2 5.9 5.5 1.2 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 AEO67256.1 - 9.3 3.8 9.4 8.9 3.8 6.5 1.1 1 0 0 1 1 1 0 Ycf1 F-box-like PF12937.2 AEO67257.1 - 0.00011 21.8 0.7 0.00027 20.5 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO67257.1 - 0.0022 17.5 0.3 0.0061 16.1 0.2 1.7 1 0 0 1 1 1 1 F-box domain Myosin_tail_1 PF01576.14 AEO67259.1 - 2.5e-05 22.2 67.6 0.0093 13.7 14.1 2.5 1 1 1 2 2 2 2 Myosin tail Tropomyosin PF00261.15 AEO67259.1 - 4.5e-05 22.6 11.3 4.5e-05 22.6 7.9 3.4 1 1 2 3 3 2 2 Tropomyosin Spc7 PF08317.6 AEO67259.1 - 9e-05 21.2 20.2 9e-05 21.2 14.0 3.0 1 1 2 3 3 3 1 Spc7 kinetochore protein Reo_sigmaC PF04582.7 AEO67259.1 - 0.0008 18.6 19.0 0.00083 18.6 3.4 3.0 1 1 2 3 3 3 1 Reovirus sigma C capsid protein IncA PF04156.9 AEO67259.1 - 0.0014 18.2 21.5 0.0014 18.2 14.9 3.7 1 1 3 4 4 4 2 IncA protein ADIP PF11559.3 AEO67259.1 - 0.0016 18.3 8.9 0.0016 18.3 6.2 4.6 1 1 3 4 4 3 2 Afadin- and alpha -actinin-Binding DUF1474 PF07342.6 AEO67259.1 - 0.0024 18.0 1.1 0.0096 16.1 0.8 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1474) Filament PF00038.16 AEO67259.1 - 0.0031 17.0 14.5 0.0031 17.0 10.1 3.0 1 1 1 2 2 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.4 AEO67259.1 - 0.0083 15.9 15.4 0.0083 15.9 10.7 4.5 1 1 3 4 4 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 AEO67259.1 - 0.0085 15.9 14.5 0.0085 15.9 10.0 3.7 1 1 1 3 3 3 2 Autophagy protein 16 (ATG16) DUF641 PF04859.7 AEO67259.1 - 0.0099 15.6 3.1 0.0099 15.6 2.2 4.3 1 1 3 4 4 3 1 Plant protein of unknown function (DUF641) Fib_alpha PF08702.5 AEO67259.1 - 0.012 15.7 9.8 0.012 15.7 6.8 3.5 2 1 1 4 4 3 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.3 AEO67259.1 - 0.012 15.3 15.7 0.012 15.3 10.9 4.7 1 1 3 4 4 3 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.7 AEO67259.1 - 0.013 15.9 7.6 0.013 15.9 5.3 5.4 3 1 2 5 5 3 0 SlyX M_domain PF12938.2 AEO67259.1 - 0.014 15.2 1.7 0.014 15.2 1.2 2.3 2 1 0 2 2 2 0 M domain of GW182 GAS PF13851.1 AEO67259.1 - 0.023 13.8 55.4 0.015 14.4 10.4 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 AEO67259.1 - 0.027 14.3 68.5 0.015 15.1 5.2 4.7 1 1 3 4 4 3 0 Tropomyosin like DUF812 PF05667.6 AEO67259.1 - 0.029 12.9 47.8 0.16 10.4 33.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Tektin PF03148.9 AEO67259.1 - 0.055 11.9 46.7 0.22 10.0 16.9 3.3 1 1 2 3 3 3 0 Tektin family Troponin PF00992.15 AEO67259.1 - 0.16 12.0 58.8 0.091 12.8 9.2 6.3 1 1 4 5 5 5 0 Troponin Tup_N PF08581.5 AEO67259.1 - 0.19 11.9 35.7 0.079 13.1 0.3 5.5 2 2 2 5 5 5 0 Tup N-terminal DUF4200 PF13863.1 AEO67259.1 - 1.9 8.4 60.2 0.014 15.3 9.0 4.6 1 1 4 5 5 4 0 Domain of unknown function (DUF4200) zf-C4H2 PF10146.4 AEO67259.1 - 2.8 7.8 41.3 0.083 12.9 10.3 2.6 1 1 0 2 2 2 0 Zinc finger-containing protein AAA_13 PF13166.1 AEO67259.1 - 3.2 6.0 52.2 0.013 13.9 10.5 2.6 1 1 1 2 2 1 0 AAA domain HrpB7 PF09486.5 AEO67259.1 - 5.1 7.0 62.8 0.43 10.4 3.8 5.4 2 1 3 6 6 6 0 Bacterial type III secretion protein (HrpB7) HOOK PF05622.7 AEO67259.1 - 7.3 4.2 52.3 68 1.0 35.3 2.1 1 1 0 1 1 1 0 HOOK protein RTBV_P46 PF06216.6 AEO67259.1 - 7.6 5.2 11.5 3.1 6.5 0.5 3.1 2 1 1 3 3 3 0 Rice tungro bacilliform virus P46 protein ERM PF00769.14 AEO67259.1 - 9.5 5.6 69.4 0.2 11.1 13.6 3.6 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Atg14 PF10186.4 AEO67259.1 - 9.9 5.0 48.3 0.45 9.4 10.7 3.4 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_M20 PF01546.23 AEO67260.1 - 1.2e-25 90.1 0.1 2.1e-25 89.3 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AEO67260.1 - 1.3e-13 50.6 0.0 4.4e-13 48.9 0.0 2.0 2 1 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 AEO67260.1 - 0.0002 21.1 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PspB PF06667.7 AEO67261.1 - 0.0014 18.5 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Phage shock protein B TMEM154 PF15102.1 AEO67261.1 - 0.0087 15.7 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF1183 PF06682.7 AEO67261.1 - 0.0089 15.6 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) DUF4448 PF14610.1 AEO67261.1 - 0.02 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SKG6 PF08693.5 AEO67261.1 - 0.099 11.9 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GFA PF04828.9 AEO67262.1 - 6.3e-07 29.2 4.7 6.3e-07 29.2 3.2 2.0 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Abhydrolase_3 PF07859.8 AEO67264.1 - 1.9e-32 112.5 0.0 3.9e-32 111.5 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO67264.1 - 1.8e-06 27.7 0.0 2.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 AEO67264.1 - 4.6e-06 25.6 0.0 1.4e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.2 AEO67264.1 - 4.6e-06 26.6 1.8 6.4e-06 26.2 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 AEO67264.1 - 3.3e-05 22.5 0.0 6.1e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Thioesterase PF00975.15 AEO67264.1 - 0.00054 20.2 0.0 0.00084 19.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.16 AEO67264.1 - 0.00059 19.1 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 AEO67264.1 - 0.022 14.2 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Glyco_hydro_31 PF01055.21 AEO67265.1 - 4.7e-91 305.8 2.5 6.1e-91 305.4 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Clr5 PF14420.1 AEO67266.1 - 9.4e-22 76.6 0.5 3.1e-21 75.0 0.6 1.7 2 0 0 2 2 2 1 Clr5 domain Hydrolase_6 PF13344.1 AEO67269.1 - 3.2e-23 81.5 0.0 5.6e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO67269.1 - 6.6e-18 64.1 0.0 3.3e-17 61.9 0.0 2.2 2 1 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 AEO67269.1 - 0.00011 22.5 0.0 0.18 12.0 0.0 2.7 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AEO67269.1 - 0.012 16.0 0.0 0.067 13.5 0.0 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.16 AEO67271.1 - 2.4e-57 193.9 0.0 2.7e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.8 AEO67272.1 - 7.2e-19 67.9 0.0 9.5e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO67272.1 - 3e-10 40.4 0.1 5.3e-10 39.5 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding DUF3394 PF11874.3 AEO67272.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) SchA_CurD PF04486.7 AEO67272.1 - 0.077 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 SchA/CurD like domain Mem_trans PF03547.13 AEO67273.1 - 1.9e-24 85.7 0.3 2.4e-24 85.3 0.2 1.1 1 0 0 1 1 1 1 Membrane transport protein NAD_binding_10 PF13460.1 AEO67274.1 - 1.9e-12 47.6 0.2 2.5e-12 47.1 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding DUF605 PF04652.11 AEO67278.1 - 0.085 12.2 31.8 0.1 11.9 22.0 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 AEO67278.1 - 8.9 6.1 11.8 11 5.8 8.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Abhydrolase_6 PF12697.2 AEO67280.1 - 2e-25 89.9 0.0 2.5e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO67280.1 - 4.2e-20 72.3 0.0 5.7e-19 68.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO67280.1 - 2.1e-09 37.3 0.0 2.1e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 AEO67280.1 - 8.4e-06 24.4 0.0 1.2e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Ndr family FAD_binding_4 PF01565.18 AEO67281.1 - 7.7e-28 96.7 0.1 1.5e-27 95.7 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 AEO67281.1 - 8.8e-22 77.6 0.1 1.4e-21 76.9 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain DUF4660 PF15559.1 AEO67282.1 - 4.8 7.3 9.0 0.76 9.8 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) Ank_2 PF12796.2 AEO67283.1 - 2.4e-38 130.3 6.4 8.1e-15 54.9 0.0 5.3 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 AEO67283.1 - 7.8e-33 110.6 10.9 4.2e-05 23.1 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 AEO67283.1 - 3.4e-23 81.1 10.1 6.4e-06 26.2 0.1 7.5 7 1 1 8 8 8 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO67283.1 - 1e-22 80.0 7.3 1.8e-05 25.1 0.1 6.9 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO67283.1 - 1.3e-20 71.4 10.0 0.0071 16.4 0.0 9.0 9 0 0 9 9 9 5 Ankyrin repeat F-box-like PF12937.2 AEO67283.1 - 0.0032 17.1 0.0 0.007 16.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like Fip1 PF05182.8 AEO67284.1 - 1.8e-21 75.1 1.0 3.2e-21 74.2 0.7 1.5 1 0 0 1 1 1 1 Fip1 motif Nucleoporin_FG PF13634.1 AEO67285.1 - 2.4e-22 79.2 89.9 1e-13 51.4 32.4 3.2 2 1 1 3 3 3 2 Nucleoporin FG repeat region Serglycin PF04360.7 AEO67285.1 - 0.00078 19.2 0.1 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Serglycin DUF3584 PF12128.3 AEO67285.1 - 0.0059 14.0 1.2 0.36 8.1 0.1 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3584) AbiH PF14253.1 AEO67285.1 - 0.038 13.6 0.0 0.091 12.3 0.0 1.5 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH HrpB7 PF09486.5 AEO67285.1 - 0.1 12.5 0.5 23 4.9 0.0 2.8 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Prominin PF05478.6 AEO67285.1 - 0.47 7.9 1.1 1 6.8 0.1 1.7 2 0 0 2 2 2 0 Prominin RNA_pol_3_Rpc31 PF11705.3 AEO67286.1 - 4.9e-23 82.2 39.3 2.1e-21 76.9 27.2 2.0 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF1470 PF07336.6 AEO67286.1 - 0.061 13.6 1.2 0.11 12.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) Autophagy_N PF03986.8 AEO67286.1 - 5.1 6.8 8.7 8.5 6.1 6.0 1.3 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain DAZAP2 PF11029.3 AEO67287.1 - 0.044 14.2 0.1 5 7.5 0.0 2.4 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) Sec7 PF01369.15 AEO67288.1 - 1.7e-64 216.9 4.3 1.8e-64 216.9 0.2 2.9 3 1 1 4 4 4 1 Sec7 domain DUF1981 PF09324.5 AEO67288.1 - 5.4e-32 109.1 4.4 1.2e-31 108.0 0.1 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Sec7_N PF12783.2 AEO67288.1 - 4e-16 58.8 4.9 7.6e-16 57.9 0.1 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal 2-oxoacid_dh PF00198.18 AEO67289.1 - 4.4e-76 255.1 0.0 5.7e-76 254.8 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 AEO67289.1 - 1e-18 66.7 1.5 2.4e-18 65.5 1.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 AEO67289.1 - 7.2e-12 44.7 0.4 2.7e-11 42.8 0.3 2.0 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.3 AEO67289.1 - 0.0025 18.1 0.1 0.0045 17.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3614) AATase PF07247.7 AEO67289.1 - 0.22 10.0 0.0 8.8 4.7 0.0 2.5 3 0 0 3 3 3 0 Alcohol acetyltransferase Fungal_trans PF04082.13 AEO67291.1 - 8.9e-16 57.5 0.0 1.3e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO67291.1 - 1.3e-08 34.6 11.5 3.1e-08 33.3 7.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 AEO67291.1 - 3.5 7.8 9.3 7.6 6.7 6.4 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region p450 PF00067.17 AEO67292.1 - 3.3e-41 141.2 0.0 4.5e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AAA_13 PF13166.1 AEO67294.1 - 0.017 13.6 2.1 0.024 13.1 1.5 1.2 1 0 0 1 1 1 0 AAA domain Filament PF00038.16 AEO67294.1 - 0.11 11.9 13.7 0.06 12.7 1.8 2.5 1 1 1 2 2 2 0 Intermediate filament protein DUF1664 PF07889.7 AEO67294.1 - 0.21 11.3 0.3 0.6 9.9 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 AEO67294.1 - 0.25 10.4 2.4 3.6 6.6 0.5 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF972 PF06156.8 AEO67294.1 - 1.8 8.9 12.6 5.2 7.4 1.5 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF972) APG6 PF04111.7 AEO67294.1 - 3.1 6.7 10.2 4.3 6.2 6.2 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 ERM PF00769.14 AEO67294.1 - 7 6.1 21.1 0.26 10.7 9.5 2.3 2 1 0 2 2 2 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.14 AEO67294.1 - 9.7 3.8 4.8 17 3.1 3.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SET PF00856.23 AEO67295.1 - 0.0011 19.2 0.0 0.0043 17.3 0.0 2.0 3 0 0 3 3 3 1 SET domain Ank_2 PF12796.2 AEO67296.1 - 0.0014 18.9 0.0 0.056 13.7 0.0 2.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AEO67296.1 - 0.12 12.6 1.4 25 5.4 0.1 4.1 4 0 0 4 4 4 0 Ankyrin repeat Ferritin_2 PF13668.1 AEO67297.1 - 3e-17 62.8 0.0 5.2e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain p450 PF00067.17 AEO67298.1 - 3.7e-51 174.0 0.0 5.2e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 2-Hacid_dh_C PF02826.14 AEO67299.1 - 6.4e-42 142.7 0.0 6.3e-25 87.3 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AEO67299.1 - 0.0097 15.3 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Oxidored_nitro PF00148.14 AEO67299.1 - 0.026 13.1 0.0 0.029 12.9 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase RHS_repeat PF05593.9 AEO67299.1 - 0.038 14.1 0.6 0.12 12.6 0.4 1.8 1 0 0 1 1 1 0 RHS Repeat 3HCDH_N PF02737.13 AEO67299.1 - 0.051 13.2 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 AEO67299.1 - 0.14 11.7 0.2 0.29 10.6 0.1 1.5 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase zf-PHD-like PF15446.1 AEO67300.1 - 0.035 13.3 0.3 0.055 12.7 0.2 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Glyco_hydro_18 PF00704.23 AEO67301.1 - 9.6e-99 331.0 7.7 1.1e-98 330.8 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Fungal_trans PF04082.13 AEO67302.1 - 7e-20 70.9 0.5 1.4e-19 69.9 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO67302.1 - 6.2e-09 35.6 10.4 1e-08 34.9 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 AEO67303.1 - 3e-74 249.7 2.6 2.8e-73 246.5 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 AEO67303.1 - 4.2e-55 186.1 1.6 1.5e-54 184.4 0.1 2.8 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 AEO67303.1 - 1.9e-52 178.6 0.5 3.4e-52 177.7 0.4 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 AEO67303.1 - 3.8e-49 167.4 0.4 3.8e-49 167.4 0.3 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase adh_short PF00106.20 AEO67303.1 - 1.4e-43 148.6 3.6 8.5e-42 142.9 0.2 3.7 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 AEO67303.1 - 8.9e-42 141.7 0.1 9.4e-41 138.3 0.0 2.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 AEO67303.1 - 9e-21 73.7 0.1 9e-21 73.7 0.1 4.1 5 0 0 5 5 4 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 AEO67303.1 - 4.3e-19 68.8 0.0 1e-17 64.4 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 AEO67303.1 - 1.1e-15 58.6 0.0 9.1e-15 55.6 0.0 2.7 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 AEO67303.1 - 5.9e-12 45.6 0.0 1.5e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO67303.1 - 1.3e-07 32.1 0.0 7.8e-07 29.6 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO67303.1 - 2.1e-07 31.3 0.0 1.1e-06 29.0 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO67303.1 - 2e-06 27.1 0.0 7.3e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 AEO67303.1 - 3.4e-06 26.7 0.0 1.3e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 AEO67303.1 - 6.6e-06 26.3 0.1 1.7e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 AEO67303.1 - 3.6e-05 24.0 0.0 0.00016 22.0 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Saccharop_dh PF03435.13 AEO67303.1 - 0.00022 20.3 0.7 0.0005 19.1 0.1 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase Thiolase_N PF00108.18 AEO67303.1 - 0.00023 20.2 0.0 0.00052 19.0 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.16 AEO67303.1 - 0.00028 20.4 0.2 0.028 13.8 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_N PF08240.7 AEO67303.1 - 0.0014 18.3 0.1 0.0034 17.1 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CoA_trans PF01144.18 AEO67303.1 - 0.0024 17.0 0.0 1.1 8.4 0.0 2.4 2 0 0 2 2 2 1 Coenzyme A transferase Polysacc_synt_2 PF02719.10 AEO67303.1 - 0.013 14.4 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 AEO67303.1 - 0.016 15.0 0.0 0.075 12.7 0.0 2.0 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 AEO67303.1 - 0.03 13.0 0.1 0.052 12.2 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 AEO67303.1 - 0.059 13.4 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_8 PF05148.10 AEO67303.1 - 0.36 10.4 0.0 0.68 9.5 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase adh_short PF00106.20 AEO67304.1 - 8.7e-08 32.2 0.2 2e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO67304.1 - 2.2e-05 24.2 0.1 5e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 AEO67304.1 - 0.16 10.8 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3716 PF12511.3 AEO67305.1 - 7.6e-15 54.2 8.0 1.2e-14 53.6 5.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF2724 PF10893.3 AEO67305.1 - 0.12 12.2 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) MIP-T3 PF10243.4 AEO67305.1 - 1.1 7.6 6.7 1.3 7.4 4.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 zf-C2HC5 PF06221.8 AEO67306.1 - 3.2e-22 78.0 3.6 5e-22 77.4 2.5 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type SIR2 PF02146.12 AEO67307.1 - 7e-30 104.0 0.0 8e-09 35.4 0.0 3.3 3 0 0 3 3 3 3 Sir2 family Peptidase_S8 PF00082.17 AEO67310.1 - 0.00021 20.5 0.7 0.00031 19.9 0.5 1.4 1 1 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.6 AEO67311.1 - 4.2e-31 107.9 0.0 8.2e-31 106.9 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain DUF605 PF04652.11 AEO67312.1 - 0.16 11.3 11.2 0.18 11.2 7.8 1.1 1 0 0 1 1 1 0 Vta1 like Tachystatin_B PF11478.3 AEO67313.1 - 0.33 10.7 4.1 0.84 9.4 2.8 1.7 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B HemY_N PF07219.8 AEO67314.1 - 0.47 10.0 0.0 0.47 10.0 0.0 4.3 4 1 0 4 4 4 0 HemY protein N-terminus AAA_12 PF13087.1 AEO67316.1 - 4.4e-23 81.7 0.0 7.3e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 AEO67316.1 - 1.3e-07 31.4 0.0 5.5e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 AEO67316.1 - 0.00013 21.9 0.0 0.0003 20.9 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 AEO67316.1 - 0.0045 16.7 0.0 0.18 11.6 0.0 3.0 3 0 0 3 3 3 1 Part of AAA domain Viral_helicase1 PF01443.13 AEO67316.1 - 0.0045 16.5 0.1 0.025 14.0 0.0 2.1 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 AEO67316.1 - 0.0086 15.4 0.0 0.027 13.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain HAUS-augmin3 PF14932.1 AEO67316.1 - 0.13 11.4 0.0 1 8.5 0.0 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Nop14 PF04147.7 AEO67317.1 - 0.025 12.5 0.3 0.028 12.3 0.2 1.0 1 0 0 1 1 1 0 Nop14-like family Lactamase_B_2 PF12706.2 AEO67318.1 - 6.8e-21 74.7 0.0 2.2e-20 73.0 0.0 1.7 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AEO67318.1 - 1.1e-10 41.4 0.0 1.9e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AEO67318.1 - 0.015 14.9 15.4 0.15 11.7 4.5 3.6 1 1 1 2 2 2 0 Metallo-beta-lactamase superfamily HET PF06985.6 AEO67319.1 - 1.1e-23 83.9 0.7 1.8e-23 83.2 0.5 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ldh_1_N PF00056.18 AEO67320.1 - 2.3e-44 150.6 0.0 4.6e-44 149.6 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 AEO67320.1 - 3e-43 147.5 0.0 4.4e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 AEO67320.1 - 1.4e-05 23.9 0.0 2.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 AEO67320.1 - 0.084 13.1 0.6 0.39 11.0 0.0 2.3 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Hydrolase PF00702.21 AEO67321.1 - 5.2e-24 85.8 0.0 2e-23 83.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 AEO67321.1 - 7.2e-23 80.8 0.0 2e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 AEO67321.1 - 8.1e-20 71.8 0.0 1.9e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO67321.1 - 7.9e-06 25.7 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AEO67321.1 - 0.0012 18.4 0.1 0.029 13.9 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AEO67321.1 - 0.029 13.6 0.3 1.3 8.2 0.0 2.9 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase Whi5 PF08528.6 AEO67324.1 - 1.7e-10 40.2 0.0 3e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Whi5 like AA_permease_2 PF13520.1 AEO67325.1 - 9.5e-81 271.5 29.3 1.2e-80 271.1 20.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO67325.1 - 1.1e-16 60.3 27.7 3.6e-16 58.5 19.2 1.8 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 AEO67325.1 - 0.0028 16.1 9.2 0.011 14.3 6.4 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Tyrosinase PF00264.15 AEO67326.1 - 3.5e-30 105.8 0.2 4.9e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase V-SNARE_C PF12352.3 AEO67327.1 - 1.1e-14 54.2 0.8 4.2e-14 52.3 0.1 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 AEO67327.1 - 0.00018 21.1 0.0 0.00056 19.5 0.0 1.8 2 0 0 2 2 2 1 Sec20 Sigma70_r4 PF04545.11 AEO67327.1 - 0.0069 15.6 0.1 0.017 14.3 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 CHASE3 PF05227.8 AEO67327.1 - 0.022 14.4 5.6 0.05 13.2 3.9 1.5 1 0 0 1 1 1 0 CHASE3 domain Mito_fiss_reg PF05308.6 AEO67327.1 - 0.11 11.8 1.6 0.15 11.3 0.9 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator AJAP1_PANP_C PF15298.1 AEO67327.1 - 0.4 10.5 3.6 1 9.2 0.1 2.2 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Cortex-I_coil PF09304.5 AEO67327.1 - 0.68 10.0 4.0 3.5 7.7 1.3 2.4 2 1 0 2 2 2 0 Cortexillin I, coiled coil FlgN PF05130.7 AEO67327.1 - 1.4 9.1 8.2 0.77 9.9 4.1 1.7 2 0 0 2 2 2 0 FlgN protein DivIC PF04977.10 AEO67327.1 - 5.6 6.5 9.1 4.4 6.8 0.0 2.8 3 0 0 3 3 3 0 Septum formation initiator TPK_B1_binding PF04265.9 AEO67328.1 - 5.4e-23 80.4 0.0 8.5e-23 79.8 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 AEO67328.1 - 9.6e-23 80.0 0.1 3.1e-22 78.4 0.1 1.7 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TSA PF03249.8 AEO67328.1 - 7.3 5.0 7.4 9.9 4.5 5.1 1.1 1 0 0 1 1 1 0 Type specific antigen CHCH PF06747.8 AEO67329.1 - 1.4e-06 28.0 6.4 2.2e-06 27.4 4.4 1.3 1 0 0 1 1 1 1 CHCH domain DUF1510 PF07423.6 AEO67330.1 - 0.093 12.0 6.5 0.12 11.6 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CAF-1_p150 PF11600.3 AEO67330.1 - 0.1 11.9 11.3 0.16 11.3 7.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1682 PF07946.9 AEO67330.1 - 0.25 10.1 2.1 0.29 9.9 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Daxx PF03344.10 AEO67330.1 - 0.28 9.6 7.0 0.34 9.3 4.8 1.2 1 0 0 1 1 1 0 Daxx Family Macoilin PF09726.4 AEO67330.1 - 0.33 9.1 3.2 0.4 8.9 2.2 1.2 1 0 0 1 1 1 0 Transmembrane protein CT47 PF15623.1 AEO67330.1 - 0.89 9.2 19.0 1.2 8.7 13.2 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 G0-G1_switch_2 PF15103.1 AEO67330.1 - 6.4 7.0 7.1 11 6.3 2.3 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 Fungal_trans_2 PF11951.3 AEO67331.1 - 0.026 13.1 0.0 0.026 13.1 0.0 1.0 1 0 0 1 1 1 0 Fungal specific transcription factor domain Oxidored_FMN PF00724.15 AEO67332.1 - 2.5e-68 230.5 0.0 3e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 AEO67332.1 - 7.8e-06 24.9 0.4 0.00061 18.7 0.0 2.2 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) Mannosyl_trans3 PF11051.3 AEO67333.1 - 6.5e-38 130.6 0.1 5.8e-37 127.5 0.1 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative Pkinase PF00069.20 AEO67335.1 - 2.6e-25 89.0 0.0 4.9e-25 88.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO67335.1 - 2.1e-13 49.9 0.0 3.2e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO67335.1 - 0.00087 18.4 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO67335.1 - 0.0032 17.2 0.1 0.0065 16.2 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 AEO67335.1 - 0.059 12.1 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase adh_short PF00106.20 AEO67337.1 - 6.1e-15 55.5 4.7 1.2e-14 54.6 3.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO67337.1 - 3.4e-07 30.1 1.9 5.4e-07 29.4 1.3 1.3 1 0 0 1 1 1 1 KR domain SWIM PF04434.12 AEO67338.1 - 0.26 10.8 1.2 0.57 9.7 0.8 1.6 1 0 0 1 1 1 0 SWIM zinc finger Myb_DNA-bind_3 PF12776.2 AEO67339.1 - 9.2e-20 71.0 0.6 9.2e-20 71.0 0.4 2.1 2 0 0 2 2 1 1 Myb/SANT-like DNA-binding domain Suf PF05843.9 AEO67339.1 - 0.045 13.4 11.3 0.074 12.7 7.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4175 PF13779.1 AEO67339.1 - 0.063 10.9 20.3 0.08 10.6 14.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) BAF1_ABF1 PF04684.8 AEO67339.1 - 0.18 10.6 18.0 0.27 10.0 12.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CDK2AP PF09806.4 AEO67339.1 - 0.29 11.3 18.3 0.61 10.2 12.7 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein EPL1 PF10513.4 AEO67339.1 - 0.53 10.5 8.9 2.5 8.3 5.0 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like UPF0560 PF10577.4 AEO67339.1 - 0.67 8.1 11.6 0.93 7.6 8.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PAT1 PF09770.4 AEO67339.1 - 0.84 7.7 40.9 1.1 7.3 28.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ctr PF04145.10 AEO67339.1 - 1.1 9.2 3.3 3.4 7.7 2.3 1.8 1 0 0 1 1 1 0 Ctr copper transporter family FAM60A PF15396.1 AEO67339.1 - 2.5 7.8 5.9 5.4 6.6 4.1 1.5 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.7 AEO67339.1 - 3 7.6 10.4 6.2 6.6 7.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 AEO67339.1 - 3 5.3 7.6 4 4.9 5.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BRF1 PF07741.8 AEO67339.1 - 4.2 7.6 13.7 0.29 11.3 3.5 3.0 3 0 0 3 3 3 0 Brf1-like TBP-binding domain DUF4557 PF15101.1 AEO67339.1 - 7 6.4 13.7 14 5.4 9.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Asp PF00026.18 AEO67340.1 - 3e-63 213.9 0.8 3.5e-63 213.7 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO67340.1 - 5.6e-07 29.6 0.0 6.7e-06 26.1 0.0 2.6 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO67340.1 - 0.0006 20.2 1.9 0.42 11.1 0.3 3.0 2 1 0 2 2 2 2 Aspartyl protease Glyco_hydro_3 PF00933.16 AEO67341.1 - 1.6e-89 299.8 0.0 2.7e-89 299.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO67341.1 - 3.7e-58 196.7 1.4 3.7e-58 196.7 0.9 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO67341.1 - 3.2e-25 87.8 0.0 7e-25 86.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Zn_clus PF00172.13 AEO67342.1 - 2e-09 37.1 35.3 0.00012 21.8 7.8 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.14 AEO67342.1 - 2.2 8.7 10.9 4.6 7.7 7.5 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4206 PF13901.1 AEO67342.1 - 2.8 7.4 13.6 4.6 6.7 9.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4206) Peptidase_M54 PF07998.6 AEO67345.1 - 1.2e-09 38.2 0.6 2e-09 37.4 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M54 Reprolysin_2 PF13574.1 AEO67345.1 - 0.017 15.1 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 AEO67345.1 - 0.048 13.1 0.0 0.1 12.1 0.0 1.5 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 AEO67345.1 - 0.06 13.2 0.1 0.21 11.4 0.1 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 AEO67345.1 - 0.089 13.3 0.0 0.2 12.1 0.0 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.14 AEO67345.1 - 0.22 11.1 1.2 0.35 10.4 0.7 1.4 1 1 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Aminotran_5 PF00266.14 AEO67346.1 - 3.2e-21 75.5 0.0 5.1e-21 74.8 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V AAA_18 PF13238.1 AEO67347.1 - 1.4e-11 44.7 0.0 2.3e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AEO67347.1 - 3.1e-11 43.3 0.2 1.4e-10 41.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO67347.1 - 2.1e-10 41.4 0.0 3.3e-10 40.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 AEO67347.1 - 1.5e-09 37.8 0.0 1.2e-05 25.2 0.0 2.1 2 0 0 2 2 2 2 Shikimate kinase AAA_28 PF13521.1 AEO67347.1 - 0.00023 21.1 0.0 0.0012 18.8 0.0 1.9 1 1 0 2 2 2 1 AAA domain AAA PF00004.24 AEO67347.1 - 0.00038 20.6 0.0 0.0013 18.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 AEO67347.1 - 0.00044 20.1 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AEO67347.1 - 0.0025 16.9 0.0 0.0053 15.8 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin Rad17 PF03215.10 AEO67347.1 - 0.0033 16.1 0.0 0.0049 15.6 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 AEO67347.1 - 0.0034 17.3 0.1 0.013 15.5 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 AEO67347.1 - 0.0065 16.1 0.0 0.009 15.7 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase CoaE PF01121.15 AEO67347.1 - 0.012 14.9 0.0 0.039 13.3 0.0 1.9 2 0 0 2 2 2 0 Dephospho-CoA kinase Cytidylate_kin2 PF13189.1 AEO67347.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.6 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_22 PF13401.1 AEO67347.1 - 0.047 13.8 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 AEO67347.1 - 0.054 13.1 0.0 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_25 PF13481.1 AEO67347.1 - 0.054 12.8 3.3 0.91 8.8 0.3 3.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AEO67347.1 - 0.057 13.6 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA helicase PRK PF00485.13 AEO67347.1 - 0.064 12.8 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family IPT PF01745.11 AEO67347.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Isopentenyl transferase RhoGAP PF00620.22 AEO67348.1 - 9.7e-14 51.2 0.0 1.4e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Epimerase PF01370.16 AEO67349.1 - 7e-11 42.0 2.9 3.5e-05 23.3 0.3 3.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO67349.1 - 6.9e-07 28.4 0.0 0.024 13.5 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 AEO67349.1 - 7.7e-06 24.7 0.0 0.00063 18.5 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 AEO67349.1 - 0.00067 19.7 0.0 0.012 15.6 0.0 2.6 2 1 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 AEO67349.1 - 0.03 14.2 0.0 2.1 8.2 0.0 2.4 1 1 1 2 2 2 0 short chain dehydrogenase KR PF08659.5 AEO67349.1 - 0.043 13.4 0.0 0.69 9.5 0.0 2.1 1 1 1 2 2 2 0 KR domain NmrA PF05368.8 AEO67349.1 - 0.076 12.2 0.0 0.23 10.6 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family FAD_binding_3 PF01494.14 AEO67350.1 - 1e-13 51.1 4.4 6.6e-06 25.4 0.9 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 AEO67350.1 - 0.00015 20.7 0.1 0.0005 19.0 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 AEO67350.1 - 0.0012 18.6 0.0 0.0035 17.1 0.0 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 AEO67350.1 - 0.0085 16.4 0.9 0.0085 16.4 0.6 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO67350.1 - 0.012 15.5 0.3 0.035 14.1 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AEO67350.1 - 0.051 13.6 0.1 0.41 10.6 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 AEO67350.1 - 0.15 10.8 0.1 5.2 5.8 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Methyltransf_23 PF13489.1 AEO67352.1 - 3.4e-18 65.8 0.0 5.3e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO67352.1 - 2.5e-08 33.6 0.0 1.8e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO67352.1 - 4.1e-08 33.7 0.0 8.8e-07 29.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO67352.1 - 6.1e-05 23.4 0.0 0.00014 22.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 AEO67352.1 - 0.01 15.8 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 AEO67352.1 - 0.045 13.7 0.0 0.15 12.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 AEO67352.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 AEO67352.1 - 0.18 10.9 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MFS_1 PF07690.11 AEO67353.1 - 1.8e-29 102.5 25.1 1.8e-29 102.5 17.4 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Defensin_2 PF01097.13 AEO67354.1 - 1e-05 25.1 1.8 1e-05 25.1 1.2 2.9 2 1 0 2 2 2 1 Arthropod defensin Gamma-thionin PF00304.15 AEO67354.1 - 0.072 13.1 23.6 0.14 12.2 3.0 2.8 2 1 0 2 2 2 0 Gamma-thionin family SLR1-BP PF07333.7 AEO67354.1 - 0.54 10.5 19.4 1.2 9.4 2.5 2.5 2 1 0 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) DUF2667 PF10868.3 AEO67354.1 - 2.3 8.6 17.4 0.27 11.6 5.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2667) Toxin_3 PF00537.13 AEO67354.1 - 5.1 7.0 17.4 4.7 7.1 1.5 2.3 2 0 0 2 2 2 0 Scorpion toxin-like domain Macin PF14865.1 AEO67354.1 - 6.3 6.9 18.5 0.51 10.4 2.6 2.6 2 0 0 2 2 2 0 Macin FAD_binding_4 PF01565.18 AEO67355.1 - 8.6e-18 64.1 3.3 1e-17 63.9 1.2 2.0 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.7 AEO67355.1 - 3.1e-11 42.9 0.0 5.7e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Pkinase PF00069.20 AEO67357.1 - 1.6e-07 30.7 0.0 2.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 AEO67357.1 - 5.5e-06 25.6 0.0 1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO67357.1 - 8.4e-05 22.4 0.4 0.00019 21.2 0.3 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 AEO67357.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.12 AEO67357.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase TPR_11 PF13414.1 AEO67361.1 - 8.6e-15 54.1 2.8 4e-10 39.1 0.5 4.5 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 AEO67361.1 - 1.6e-14 52.5 6.6 5.5e-05 22.7 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 AEO67361.1 - 3.2e-13 48.6 6.2 0.00044 19.7 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 AEO67361.1 - 1.5e-11 44.0 2.4 0.013 15.3 0.0 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 AEO67361.1 - 1e-09 38.8 1.2 1e-09 38.8 0.8 5.5 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 AEO67361.1 - 5e-09 35.2 0.3 0.0078 15.9 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 AEO67361.1 - 1e-07 32.1 0.2 0.00036 20.8 0.1 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 AEO67361.1 - 1.9e-06 27.2 4.0 0.00063 19.3 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 AEO67361.1 - 2.3e-06 27.7 0.9 0.0011 19.3 0.2 6.6 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 AEO67361.1 - 0.00017 21.5 0.4 0.038 14.1 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 AEO67361.1 - 0.0025 18.1 1.9 12 6.5 0.2 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 AEO67361.1 - 0.056 13.5 0.3 0.25 11.4 0.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 AEO67361.1 - 0.14 11.5 0.4 1.3 8.3 0.2 2.4 1 1 1 2 2 2 0 26S proteasome subunit RPN7 GYF PF02213.11 AEO67362.1 - 1.1e-17 63.3 0.0 2.1e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 GYF domain SnoaL PF07366.7 AEO67363.1 - 4.1e-06 26.3 0.0 8.4e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 AEO67363.1 - 0.0018 18.6 0.1 0.0038 17.6 0.1 1.5 1 0 0 1 1 1 1 SnoaL-like domain Abhydrolase_5 PF12695.2 AEO67363.1 - 0.0058 16.3 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3982 PF13138.1 AEO67363.1 - 0.013 15.3 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3982) Ribosomal_L6e_N PF03868.10 AEO67363.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L6, N-terminal domain 5_nucleotid_C PF02872.13 AEO67366.1 - 3.5e-38 131.0 0.0 7e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 AEO67366.1 - 2.2e-06 27.2 0.0 3.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AEO67366.1 - 0.061 13.1 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pox_A_type_inc PF04508.7 AEO67366.1 - 0.068 12.9 1.0 0.17 11.7 0.7 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Acetyltransf_1 PF00583.19 AEO67367.1 - 3.4e-13 49.4 0.1 5.7e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 AEO67367.1 - 6.4e-09 35.4 0.0 1.1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 AEO67367.1 - 0.00011 22.2 0.1 0.00034 20.7 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO67367.1 - 0.00015 21.8 0.0 0.00025 21.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AEO67367.1 - 0.00021 21.4 0.1 0.0008 19.5 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AEO67367.1 - 0.03 14.2 0.0 0.76 9.7 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.10 AEO67368.1 - 6.4e-08 32.2 3.4 1.8e-07 30.8 2.4 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AEO67368.1 - 6.8e-07 29.4 3.1 1.6e-06 28.2 2.2 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Med4 PF10018.4 AEO67368.1 - 0.035 13.5 1.4 0.055 12.8 0.9 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Ank_2 PF12796.2 AEO67369.1 - 1.2e-16 60.8 0.4 1e-05 25.7 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AEO67369.1 - 3e-16 59.4 4.0 3.6e-08 33.6 0.1 4.8 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO67369.1 - 3.9e-13 49.1 0.4 1.2e-05 25.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 AEO67369.1 - 4.4e-13 48.3 1.2 8e-06 25.4 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 AEO67369.1 - 6.1e-12 44.5 0.7 0.00031 20.6 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 AEO67369.1 - 2.5e-05 23.8 0.1 0.00015 21.3 0.1 2.4 1 1 0 1 1 1 1 KilA-N domain Hrs_helical PF12210.3 AEO67369.1 - 0.0014 18.7 3.5 0.0014 18.7 2.4 2.2 3 0 0 3 3 3 1 Hepatocyte growth factor-regulated tyrosine kinase substrate NAD_binding_7 PF13241.1 AEO67370.1 - 1.2e-33 115.4 0.0 1.6e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 AEO67370.1 - 8.1e-22 76.3 0.0 1.2e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 AEO67370.1 - 2e-14 52.2 0.1 3.2e-14 51.5 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central TrkA_N PF02254.13 AEO67370.1 - 0.012 15.6 0.2 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.16 AEO67370.1 - 0.017 14.9 1.1 0.028 14.2 0.0 1.7 1 1 1 2 2 2 0 ThiF family Shikimate_DH PF01488.15 AEO67370.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FYVE PF01363.16 AEO67371.1 - 1.6e-19 69.5 25.9 8.6e-15 54.3 4.6 2.9 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.3 AEO67371.1 - 5.1e-05 22.7 0.9 5.1e-05 22.7 0.6 2.1 2 0 0 2 2 2 1 Rabenosyn Rab binding domain zf-AN1 PF01428.11 AEO67371.1 - 0.0027 17.5 2.8 0.0027 17.5 1.9 3.5 4 0 0 4 4 4 1 AN1-like Zinc finger zf-Di19 PF05605.7 AEO67371.1 - 0.026 14.6 11.0 0.056 13.5 0.1 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding CK_II_beta PF01214.13 AEO67371.1 - 0.1 12.0 0.5 0.33 10.4 0.3 1.8 1 0 0 1 1 1 0 Casein kinase II regulatory subunit MerR-DNA-bind PF09278.6 AEO67371.1 - 6.8 7.1 14.4 0.23 11.9 0.2 3.8 4 1 0 4 4 4 0 MerR, DNA binding CENP-L PF13092.1 AEO67372.1 - 1.1e-51 174.8 0.0 2.3e-51 173.7 0.0 1.5 2 0 0 2 2 2 1 Kinetochore complex Sim4 subunit Fta1 zf-RING_2 PF13639.1 AEO67373.1 - 8.6e-08 31.8 1.4 5.6e-07 29.2 0.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO67373.1 - 0.00014 21.7 0.1 0.00014 21.7 0.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO67373.1 - 0.00034 20.6 0.6 0.0024 17.9 0.4 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 AEO67373.1 - 0.0019 17.8 1.4 0.0035 17.0 0.0 2.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 AEO67373.1 - 0.0028 17.3 1.0 0.016 14.8 0.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) CDC37_C PF08564.5 AEO67373.1 - 0.0055 16.5 10.9 0.01 15.6 7.6 1.4 1 0 0 1 1 1 1 Cdc37 C terminal domain zf-C3HC4 PF00097.20 AEO67373.1 - 0.013 15.1 1.0 0.025 14.2 0.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO67373.1 - 0.024 14.3 0.6 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.1 AEO67373.1 - 0.031 13.8 0.6 0.07 12.7 0.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_5 PF13719.1 AEO67373.1 - 0.059 12.9 0.2 10 5.8 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain UPF0547 PF10571.4 AEO67373.1 - 0.095 12.4 2.7 5 6.9 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_4 PF13717.1 AEO67373.1 - 0.095 12.4 0.4 20 4.9 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-C3HC4_4 PF15227.1 AEO67373.1 - 0.1 12.5 2.4 0.23 11.3 0.3 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 AEO67373.1 - 0.11 12.4 0.2 0.45 10.3 0.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RNA_pol_3_Rpc31 PF11705.3 AEO67373.1 - 0.98 9.3 12.6 1.3 8.9 8.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Ribosomal_60s PF00428.14 AEO67373.1 - 6.3 7.2 17.4 13 6.3 12.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Myc_N PF01056.13 AEO67373.1 - 8.9 5.3 9.7 12 4.9 6.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region UIM PF02809.15 AEO67374.1 - 0.2 11.2 4.0 0.63 9.7 2.8 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif p450 PF00067.17 AEO67375.1 - 2.4e-64 217.5 0.0 3.4e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 AEO67376.1 - 3.9e-21 75.1 0.1 1.7e-09 36.7 0.1 3.1 3 0 0 3 3 3 3 Cytochrome P450 DUF3350 PF11830.3 AEO67376.1 - 0.11 12.4 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3350) HpaP PF09483.5 AEO67378.1 - 0.07 13.0 3.7 0.24 11.3 0.0 2.5 1 1 1 2 2 2 0 Type III secretion protein (HpaP) DnaJ_CXXCXGXG PF00684.14 AEO67378.1 - 0.077 13.0 0.4 0.14 12.2 0.3 1.4 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC PF00098.18 AEO67378.1 - 0.3 11.0 5.0 4.4 7.3 0.7 2.4 2 0 0 2 2 2 0 Zinc knuckle adh_short PF00106.20 AEO67380.1 - 7.1e-15 55.3 0.3 1.1e-14 54.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO67380.1 - 6e-07 29.2 0.3 9.5e-07 28.6 0.2 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO67380.1 - 6.2e-05 22.8 0.0 9.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AEO67380.1 - 0.00063 19.2 0.1 0.002 17.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO67380.1 - 0.011 15.7 0.3 0.026 14.5 0.1 1.6 2 0 0 2 2 2 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 AEO67380.1 - 0.013 14.6 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_4 PF07993.7 AEO67380.1 - 0.015 14.2 0.2 0.026 13.4 0.2 1.4 1 1 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.15 AEO67380.1 - 0.042 13.9 0.1 0.073 13.1 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TIR-like PF10137.4 AEO67380.1 - 0.12 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Cutinase PF01083.17 AEO67382.1 - 1.1e-54 184.8 9.5 1.3e-54 184.6 6.6 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 AEO67382.1 - 2.5e-06 27.0 0.1 3.6e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 AEO67382.1 - 0.00065 19.3 0.4 0.0059 16.1 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AEO67382.1 - 0.008 16.0 0.0 0.0099 15.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.6 AEO67382.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) ADP_ribosyl_GH PF03747.9 AEO67383.1 - 1.5e-58 198.8 6.1 2.9e-58 197.9 4.2 1.5 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Sulfate_transp PF00916.15 AEO67383.1 - 1.2e-51 175.4 0.7 1.2e-51 175.4 0.5 1.6 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 AEO67383.1 - 1.2e-26 92.2 3.9 1.2e-26 92.2 2.7 2.6 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 AEO67383.1 - 4.6e-15 55.0 0.0 8.7e-15 54.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 AEO67383.1 - 0.0031 17.5 0.0 0.015 15.2 0.0 2.3 1 1 0 1 1 1 1 STAS domain SKG6 PF08693.5 AEO67384.1 - 0.26 10.6 2.6 0.48 9.7 1.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3636 PF12331.3 AEO67385.1 - 9e-44 148.6 0.0 1.8e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Asp_Arg_Hydrox PF05118.10 AEO67385.1 - 0.035 13.9 0.1 0.9 9.3 0.1 2.2 2 0 0 2 2 2 0 Aspartyl/Asparaginyl beta-hydroxylase CTP_transf_1 PF01148.15 AEO67386.1 - 8.4e-78 261.6 28.3 1.1e-77 261.2 19.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Thiolase_N PF00108.18 AEO67387.1 - 3.1e-71 239.4 0.0 5.4e-71 238.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AEO67387.1 - 2.3e-40 136.8 0.4 2.3e-40 136.8 0.3 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 AEO67387.1 - 0.02 14.5 0.3 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Glyco_hydro_cc PF11790.3 AEO67388.1 - 1.7e-67 227.3 0.1 2e-67 227.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core EF1G PF00647.14 AEO67388.1 - 0.021 14.4 0.1 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain DUF456 PF04306.8 AEO67389.1 - 1.8e-05 24.7 0.7 2.1e-05 24.5 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF456) MFS_1 PF07690.11 AEO67389.1 - 0.15 10.7 10.0 0.17 10.5 7.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Polysacc_synt_C PF14667.1 AEO67389.1 - 1.7 8.4 6.3 2.3 8.0 4.4 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Glyco_hydro_43 PF04616.9 AEO67390.1 - 1.5e-104 349.0 0.0 3e-104 348.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 MARVEL PF01284.18 AEO67391.1 - 9.7e-05 22.2 13.5 0.00071 19.4 9.4 2.0 1 1 0 1 1 1 1 Membrane-associating domain Srg PF02118.16 AEO67391.1 - 0.031 13.7 0.8 0.042 13.2 0.6 1.1 1 0 0 1 1 1 0 Srg family chemoreceptor CorA PF01544.13 AEO67392.1 - 0.0047 16.0 2.6 0.015 14.3 1.8 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SUR7 PF06687.7 AEO67392.1 - 0.066 12.7 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 SUR7/PalI family DBINO PF13892.1 AEO67392.1 - 0.13 12.3 1.8 0.44 10.5 0.1 2.3 2 1 0 2 2 2 0 DNA-binding domain T2SF PF00482.18 AEO67392.1 - 3.5 7.5 5.9 1.2 9.0 0.2 2.8 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F p450 PF00067.17 AEO67393.1 - 9.3e-76 255.1 0.0 1.2e-75 254.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 AEO67393.1 - 7.8e-35 120.2 0.0 1.2e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 AEO67393.1 - 2.9e-25 88.9 0.1 7.7e-25 87.5 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 AEO67393.1 - 7.9e-11 42.4 0.0 2.4e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF2376 PF09550.5 AEO67393.1 - 0.045 13.9 1.8 2.3 8.4 0.0 3.6 3 0 0 3 3 3 0 Conserved hypothetical phage protein (DUF2376) Flavodoxin_5 PF12724.2 AEO67393.1 - 0.14 12.1 0.0 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain Peptidase_S10 PF00450.17 AEO67394.1 - 7.5e-82 275.7 0.3 1.2e-81 275.0 0.2 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_61 PF03443.9 AEO67395.1 - 2.2e-58 197.6 0.1 3.2e-58 197.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 AEO67395.1 - 1e-08 34.6 17.0 1e-08 34.6 11.8 3.9 4 1 0 4 4 4 1 Fungal cellulose binding domain NPCBM_assoc PF10633.4 AEO67395.1 - 0.035 14.1 0.0 0.45 10.6 0.0 2.4 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Glyco_hydro_61 PF03443.9 AEO67396.1 - 1.1e-43 149.6 0.0 1.7e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SE PF08491.5 AEO67397.1 - 1.5e-84 283.1 0.0 2e-84 282.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 AEO67397.1 - 5.3e-13 48.7 0.0 2.5e-12 46.5 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO67397.1 - 8.7e-09 34.7 2.3 4e-08 32.5 0.8 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 AEO67397.1 - 0.00011 21.4 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 AEO67397.1 - 0.00011 22.1 0.3 0.00029 20.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 AEO67397.1 - 0.00014 20.9 0.8 0.036 13.0 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.17 AEO67397.1 - 0.00016 20.6 0.0 0.0021 16.9 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 AEO67397.1 - 0.00031 19.7 0.6 0.00057 18.8 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 AEO67397.1 - 0.0007 19.6 0.0 0.0019 18.3 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 AEO67397.1 - 0.0012 17.9 0.1 0.0022 17.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 AEO67397.1 - 0.0017 18.0 0.1 0.0028 17.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 AEO67397.1 - 0.0031 16.9 0.1 0.0054 16.1 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 AEO67397.1 - 0.0035 17.2 0.1 0.0055 16.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 AEO67397.1 - 0.0084 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 AEO67397.1 - 0.0086 16.4 0.2 0.0086 16.4 0.1 2.0 3 0 0 3 3 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 AEO67397.1 - 0.06 13.1 0.6 0.13 12.1 0.4 1.5 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.9 AEO67397.1 - 0.15 10.4 0.1 0.22 9.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Zip PF02535.17 AEO67398.1 - 5.6e-57 193.1 4.9 1.7e-56 191.5 3.4 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Gly-zipper_Omp PF13488.1 AEO67398.1 - 9.6 5.9 17.4 0.16 11.6 3.5 3.4 3 0 0 3 3 3 0 Glycine zipper ketoacyl-synt PF00109.21 AEO67399.1 - 6.4e-72 242.0 0.3 1.6e-71 240.8 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 AEO67399.1 - 1e-31 109.2 0.0 2.3e-31 108.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 AEO67399.1 - 8.5e-30 104.1 0.0 2.1e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 AEO67399.1 - 1.4e-24 86.3 0.0 2.5e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 AEO67399.1 - 1.9e-13 50.4 2.5 8.1e-13 48.4 0.9 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 AEO67399.1 - 1.3e-12 47.9 0.0 4.7e-12 46.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO67399.1 - 6.9e-08 32.8 0.0 2.9e-07 30.8 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO67399.1 - 3e-07 30.1 0.0 8.2e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 AEO67399.1 - 7.6e-07 28.8 0.0 1.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 AEO67399.1 - 7.7e-07 29.1 1.2 2.1e-06 27.7 0.8 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_23 PF13489.1 AEO67399.1 - 2.1e-06 27.5 0.0 1.5e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO67399.1 - 2.2e-05 24.9 0.0 0.00011 22.7 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 AEO67399.1 - 0.0004 19.4 0.1 0.00074 18.5 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain KR PF08659.5 AEO67399.1 - 0.00068 19.3 0.1 0.0019 17.9 0.0 1.8 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 AEO67399.1 - 0.00086 18.2 0.0 0.54 9.0 0.0 2.5 2 0 0 2 2 2 2 RmlD substrate binding domain Methyltransf_25 PF13649.1 AEO67399.1 - 0.00093 19.5 0.0 0.0037 17.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO67399.1 - 0.0032 17.4 0.1 0.02 14.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 AEO67399.1 - 0.0083 15.0 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RrnaAD PF00398.15 AEO67399.1 - 0.065 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase 3Beta_HSD PF01073.14 AEO67399.1 - 0.13 10.9 0.1 0.56 8.8 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DREV PF05219.7 AEO67399.1 - 0.63 8.8 0.0 1.1 8.1 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase p450 PF00067.17 AEO67400.1 - 2.4e-57 194.5 0.0 3e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4265 PF14085.1 AEO67400.1 - 0.17 11.6 0.0 20 4.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) NmrA PF05368.8 AEO67401.1 - 1.2e-52 178.5 0.1 1.4e-52 178.2 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO67401.1 - 2.8e-13 50.2 0.2 3.8e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 AEO67401.1 - 8.8e-05 21.3 0.0 0.00012 20.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 AEO67401.1 - 0.00022 21.1 0.1 0.00037 20.4 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 AEO67401.1 - 0.0014 17.6 0.1 0.0033 16.4 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase KR PF08659.5 AEO67401.1 - 0.018 14.6 0.4 0.055 13.1 0.2 1.8 1 1 0 1 1 1 0 KR domain adh_short PF00106.20 AEO67401.1 - 0.7 9.7 5.2 0.16 11.8 0.3 2.3 4 0 0 4 4 4 0 short chain dehydrogenase Aldedh PF00171.17 AEO67402.1 - 5.3e-107 358.0 2.9 6.3e-107 357.7 2.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 AEO67402.1 - 4.3e-07 29.0 0.0 5.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) FSH1 PF03959.8 AEO67403.1 - 1.5e-28 99.7 0.0 1.9e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 AEO67403.1 - 1.4e-05 24.8 0.3 2.9e-05 23.8 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO67403.1 - 5.7e-05 23.1 7.7 0.0031 17.4 5.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 AEO67403.1 - 0.052 12.9 1.9 13 5.1 0.3 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase MFS_1 PF07690.11 AEO67404.1 - 4.7e-28 97.9 77.1 1.6e-23 83.0 35.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 AEO67404.1 - 0.00053 19.7 0.8 0.00053 19.7 0.5 2.5 3 0 0 3 3 3 1 MFS_1 like family Sugar_tr PF00083.19 AEO67404.1 - 0.061 11.8 43.6 0.16 10.5 12.5 3.3 1 1 2 3 3 3 0 Sugar (and other) transporter Methyltransf_2 PF00891.13 AEO67405.1 - 1.3e-30 106.3 0.0 3.9e-30 104.8 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 AEO67405.1 - 0.061 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain NAD_binding_8 PF13450.1 AEO67406.1 - 3.2e-15 55.8 0.1 7.1e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 AEO67406.1 - 6.6e-08 32.0 0.3 3e-07 29.8 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AEO67406.1 - 2.9e-07 29.3 0.3 4.7e-07 28.6 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 AEO67406.1 - 1.5e-06 27.5 0.0 2.6e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 AEO67406.1 - 5.5e-06 25.4 0.4 8.4e-06 24.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 AEO67406.1 - 1.6e-05 25.1 0.5 0.00015 22.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AEO67406.1 - 3.8e-05 22.7 1.6 8.3e-05 21.6 0.6 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AEO67406.1 - 0.00025 21.1 0.3 0.00065 19.8 0.1 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO67406.1 - 0.00077 19.3 0.1 0.0015 18.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.7 AEO67406.1 - 0.0017 17.7 0.1 0.0031 16.9 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain FAD_binding_3 PF01494.14 AEO67406.1 - 0.0018 17.3 0.2 0.0029 16.7 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 AEO67406.1 - 0.0059 15.5 0.3 0.0084 15.0 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 AEO67406.1 - 0.0059 15.7 0.3 0.012 14.7 0.2 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.1 AEO67406.1 - 0.011 16.0 0.2 0.073 13.3 0.1 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.11 AEO67406.1 - 0.016 14.6 0.1 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 AEO67406.1 - 0.068 12.0 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 AEO67406.1 - 0.08 12.9 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.9 AEO67406.1 - 0.12 10.9 0.1 0.29 9.7 0.2 1.5 2 0 0 2 2 2 0 Tryptophan halogenase Sugar_tr PF00083.19 AEO67407.1 - 6.8e-81 272.1 21.8 8.1e-81 271.8 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO67407.1 - 1e-17 63.9 47.8 1.3e-12 47.1 14.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ketoacyl-synt PF00109.21 AEO67408.1 - 1.8e-62 211.0 0.2 3.8e-62 210.0 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 AEO67408.1 - 9.2e-54 181.8 3.3 9.2e-54 181.8 2.3 3.0 4 0 0 4 4 4 1 KR domain PS-DH PF14765.1 AEO67408.1 - 1.2e-52 178.9 1.3 3.4e-52 177.4 0.9 1.8 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 AEO67408.1 - 5e-50 170.6 0.2 1.2e-49 169.3 0.2 1.7 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 AEO67408.1 - 3.4e-43 147.4 3.4 3.4e-43 147.4 2.3 4.4 6 0 0 6 6 5 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 AEO67408.1 - 2.3e-37 127.4 0.0 1.1e-36 125.3 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 AEO67408.1 - 7.2e-22 77.3 1.2 2.4e-21 75.6 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO67408.1 - 1.1e-12 48.9 2.4 3e-11 44.3 0.0 4.4 5 0 0 5 5 3 1 Zinc-binding dehydrogenase PP-binding PF00550.20 AEO67408.1 - 1.3e-06 28.5 0.2 3.2e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 AEO67408.1 - 0.025 13.9 0.1 0.06 12.7 0.1 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 AEO67408.1 - 0.073 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Collagen_bind_2 PF12904.2 AEO67408.1 - 0.18 11.5 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase Shikimate_DH PF01488.15 AEO67408.1 - 0.19 11.8 0.5 0.8 9.8 0.0 2.3 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase Kinesin-related PF06548.6 AEO67408.1 - 2.1 6.8 0.4 3.3 6.1 0.3 1.1 1 0 0 1 1 1 0 Kinesin-related GMC_oxred_N PF00732.14 AEO67409.1 - 5.7e-60 202.9 0.1 7.6e-60 202.5 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO67409.1 - 3.3e-37 127.9 0.8 5.1e-37 127.3 0.5 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 AEO67409.1 - 1.8e-07 30.3 2.5 0.0023 16.8 0.9 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 AEO67409.1 - 1.2e-05 24.4 4.6 0.00017 20.5 1.9 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO67409.1 - 9.4e-05 22.3 0.6 9.4e-05 22.3 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AEO67409.1 - 0.00021 21.2 1.6 0.00061 19.7 0.9 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO67409.1 - 0.00036 19.5 0.3 0.00062 18.7 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 AEO67409.1 - 0.0014 18.7 1.9 1.4 8.9 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO67409.1 - 0.0032 16.6 0.3 0.0065 15.5 0.2 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 AEO67409.1 - 0.019 13.4 0.3 0.03 12.8 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 AEO67409.1 - 0.037 13.0 2.2 0.045 12.8 0.6 1.7 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 AEO67409.1 - 0.062 11.9 2.3 0.092 11.3 1.6 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 AEO67409.1 - 0.091 12.5 0.6 0.21 11.3 0.4 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 AEO67409.1 - 1 9.8 3.9 0.72 10.2 1.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ketoacyl-synt PF00109.21 AEO67410.1 - 1.1e-75 254.3 1.0 2.2e-75 253.4 0.7 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 AEO67410.1 - 1.1e-38 131.6 0.3 2.9e-38 130.3 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 AEO67410.1 - 5.2e-28 98.0 0.3 9e-28 97.2 0.2 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 AEO67410.1 - 4.6e-19 68.7 0.1 2.1e-18 66.6 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Abhydrolase_3 PF07859.8 AEO67410.1 - 5.9e-18 65.2 0.0 8.5e-14 51.6 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold PP-binding PF00550.20 AEO67410.1 - 3.8e-14 52.6 0.1 8.8e-14 51.5 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 AEO67410.1 - 1.5e-13 50.7 0.0 8.9e-13 48.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO67410.1 - 1.1e-11 44.5 0.0 3e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_5 PF12695.2 AEO67410.1 - 7.5e-11 41.9 0.0 4.3e-10 39.5 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO67410.1 - 6.4e-10 38.6 0.0 9.8e-08 31.4 0.0 2.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Methyltransf_11 PF08241.7 AEO67410.1 - 5.9e-09 36.2 0.0 1.9e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO67410.1 - 4.8e-08 33.5 0.0 8.7e-07 29.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO67410.1 - 6.6e-07 29.6 0.1 1.2e-05 25.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Acyl_transf_1 PF00698.16 AEO67410.1 - 1.3e-06 27.9 0.1 4.4e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Acyl transferase domain DLH PF01738.13 AEO67410.1 - 2.8e-06 26.7 0.0 2e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Thiolase_N PF00108.18 AEO67410.1 - 6.2e-05 22.1 0.1 0.00011 21.2 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 AEO67410.1 - 7.8e-05 22.1 0.0 0.00034 20.0 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_28 PF02636.12 AEO67410.1 - 0.00058 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Abhydrolase_2 PF02230.11 AEO67410.1 - 0.0012 18.3 0.0 0.021 14.2 0.0 2.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Methyltransf_26 PF13659.1 AEO67410.1 - 0.0014 18.6 0.0 0.0094 15.9 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 AEO67410.1 - 0.0017 17.9 0.0 0.0045 16.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_PK PF05891.7 AEO67410.1 - 0.0022 17.3 0.0 0.0044 16.3 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Ubie_methyltran PF01209.13 AEO67410.1 - 0.0031 16.6 0.0 0.006 15.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 AEO67410.1 - 0.068 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase p450 PF00067.17 AEO67411.1 - 5.4e-58 196.6 0.0 6.7e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lactamase_B PF00753.22 AEO67412.1 - 2.1e-09 37.3 5.7 3.8e-09 36.4 4.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AEO67412.1 - 6.9e-05 22.4 0.3 0.00013 21.5 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AEO67412.1 - 0.0075 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Myb_DNA-binding PF00249.26 AEO67413.1 - 4e-32 110.0 7.1 4.7e-16 58.5 0.0 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO67413.1 - 7.1e-27 93.2 2.7 1.5e-11 44.2 0.0 3.0 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 AEO67413.1 - 0.0029 17.7 3.0 1.1 9.4 0.1 3.7 3 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 AEO67413.1 - 0.047 13.5 1.9 2.3 8.1 0.1 2.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.5 AEO67413.1 - 0.11 12.1 0.0 3.5 7.3 0.0 2.3 1 1 1 2 2 2 0 SLIDE Fungal_trans PF04082.13 AEO67414.1 - 6.4e-14 51.4 0.0 1e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO67414.1 - 8.7e-06 25.5 9.2 1.9e-05 24.4 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 AEO67415.1 - 1.5e-16 60.7 0.1 2.9e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO67415.1 - 8e-09 35.4 0.0 1.5e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO67415.1 - 2.8e-05 23.6 0.0 4.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO67415.1 - 0.0017 17.1 0.2 0.0024 16.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 AEO67415.1 - 0.0031 16.4 0.0 0.0055 15.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Transferase PF02458.10 AEO67416.1 - 4.3e-13 48.5 0.0 2.7e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 Transferase family p450 PF00067.17 AEO67417.1 - 9.3e-48 162.8 0.0 1.2e-47 162.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 AEO67418.1 - 2.7e-30 105.3 0.0 6.2e-30 104.1 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase FAD_binding_3 PF01494.14 AEO67419.1 - 6.7e-22 78.0 3.6 1.2e-20 73.9 2.1 2.6 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.19 AEO67419.1 - 2.1e-14 53.2 10.6 4.1e-08 32.5 0.3 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO67419.1 - 2.2e-08 33.4 2.9 4.8e-08 32.2 2.0 1.6 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 AEO67419.1 - 8.3e-08 31.5 2.3 0.0021 17.0 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 AEO67419.1 - 1.4e-06 28.1 2.1 3.9e-06 26.7 1.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 AEO67419.1 - 3.3e-06 26.0 1.5 0.0054 15.4 0.2 2.3 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.9 AEO67419.1 - 3.3e-06 25.8 3.9 4.3e-05 22.1 1.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 AEO67419.1 - 1.8e-05 24.9 0.0 3.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO67419.1 - 2e-05 24.5 1.6 6.7e-05 22.8 1.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AEO67419.1 - 5.9e-05 22.1 2.8 0.00017 20.5 1.4 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 AEO67419.1 - 0.0012 18.0 0.5 0.0021 17.2 0.3 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 AEO67419.1 - 0.0013 17.9 5.9 0.17 10.9 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 AEO67419.1 - 0.0026 16.9 5.2 0.0045 16.1 3.6 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO67419.1 - 0.018 15.4 4.6 0.094 13.1 1.4 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 AEO67419.1 - 0.022 14.3 2.4 0.068 12.7 0.4 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 AEO67419.1 - 0.89 9.3 5.0 7.2 6.3 0.4 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding COesterase PF00135.23 AEO67420.1 - 5.9e-91 305.7 0.0 8.1e-91 305.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO67420.1 - 5.5e-05 22.8 0.1 0.00043 19.9 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_7 PF00840.15 AEO67421.1 - 1.8e-134 448.4 18.9 4.7e-133 443.7 13.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 AEO67421.1 - 6.3e-15 54.5 7.2 6.3e-15 54.5 5.0 3.6 5 0 0 5 5 5 1 Fungal cellulose binding domain Fer4_20 PF14691.1 AEO67421.1 - 0.56 9.8 4.6 8.9 5.9 0.2 2.3 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Sporozoite_P67 PF05642.6 AEO67421.1 - 1.4 6.6 9.4 2.3 5.9 6.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-CCCH PF00642.19 AEO67423.1 - 1.3e-10 40.6 7.6 3.9e-05 23.1 1.3 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AEO67423.1 - 0.025 14.5 16.4 0.033 14.1 2.7 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type PP-binding PF00550.20 AEO67424.1 - 4e-12 46.2 0.2 5.2e-12 45.8 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 AEO67424.1 - 1.4e-05 24.9 0.2 1.7e-05 24.7 0.2 1.2 1 0 0 1 1 1 1 Acyl-carrier AFOR_C PF01314.13 AEO67424.1 - 0.12 11.0 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 Fer4 PF00037.22 AEO67425.1 - 1.4e-13 49.8 16.5 5.3e-08 32.1 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 AEO67425.1 - 6.9e-12 45.5 10.6 1.1e-11 44.8 7.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 AEO67425.1 - 6e-10 39.2 8.3 1.1e-09 38.3 5.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 AEO67425.1 - 9.8e-10 39.0 7.3 0.00021 21.9 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 AEO67425.1 - 2e-09 37.1 21.9 6.9e-08 32.1 8.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 AEO67425.1 - 8.3e-09 35.1 32.3 1.1e-05 25.1 8.7 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 AEO67425.1 - 1.1e-07 31.3 14.7 0.00043 20.0 1.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 AEO67425.1 - 1.3e-07 31.5 20.6 2.3e-05 24.3 8.1 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 AEO67425.1 - 2.3e-07 30.3 17.1 0.0012 18.6 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 AEO67425.1 - 5.2e-06 26.3 12.7 0.00057 20.0 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 AEO67425.1 - 9.8e-06 25.8 10.1 0.00097 19.4 7.9 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 AEO67425.1 - 4.8e-05 23.6 9.5 0.014 15.7 0.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 AEO67425.1 - 0.0093 16.3 15.3 0.3 11.5 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 AEO67425.1 - 0.01 16.3 12.7 0.21 12.1 1.1 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 AEO67425.1 - 0.07 13.7 16.9 0.16 12.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 AEO67425.1 - 0.11 12.5 4.8 0.26 11.4 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Acyl_transf_1 PF00698.16 AEO67427.1 - 1.8e-68 231.2 0.0 3.3e-68 230.3 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 AEO67427.1 - 1.8e-65 220.9 0.0 3.4e-65 220.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 AEO67427.1 - 4.2e-58 195.9 2.0 4.7e-58 195.8 0.1 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 AEO67427.1 - 2.9e-50 170.4 0.2 9.2e-50 168.8 0.1 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 AEO67427.1 - 2.1e-33 114.6 0.0 5.3e-33 113.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 AEO67427.1 - 9.3e-33 113.6 4.2 2.3e-30 105.7 2.9 2.6 1 1 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 AEO67427.1 - 9.6e-13 47.8 0.2 3.2e-11 42.9 0.2 3.3 4 0 0 4 4 4 1 Zinc-binding dehydrogenase PP-binding PF00550.20 AEO67427.1 - 7.4e-08 32.5 0.5 1.6e-07 31.5 0.3 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 AEO67427.1 - 7.9e-05 21.7 0.0 0.00024 20.1 0.0 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.1 AEO67427.1 - 0.00025 20.9 0.0 0.00054 19.8 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AEO67427.1 - 0.00048 19.6 0.0 0.0009 18.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 AEO67427.1 - 0.0063 15.4 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ACP_syn_III PF08545.5 AEO67427.1 - 0.021 14.4 0.2 0.15 11.7 0.1 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Shikimate_DH PF01488.15 AEO67427.1 - 0.044 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 AEO67427.1 - 0.055 13.2 0.3 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 ThiF family NAD_binding_10 PF13460.1 AEO67427.1 - 0.16 11.9 3.2 0.47 10.4 0.0 3.0 3 0 0 3 3 3 0 NADH(P)-binding OKR_DC_1 PF01276.15 AEO67427.1 - 1.2 7.6 0.0 1.8 6.9 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain FSH1 PF03959.8 AEO67428.1 - 1.6e-24 86.5 0.0 2.1e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 AEO67428.1 - 0.0015 18.4 0.0 0.032 14.0 0.0 2.2 1 1 0 2 2 2 1 Alpha/beta hydrolase family PE-PPE PF08237.6 AEO67428.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 PE-PPE domain EF-hand_7 PF13499.1 AEO67428.1 - 0.11 12.6 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair GEMIN8 PF15348.1 AEO67429.1 - 0.57 10.2 8.0 0.85 9.6 5.6 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 BAF1_ABF1 PF04684.8 AEO67429.1 - 2.4 6.9 14.0 2.7 6.7 9.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ripply PF14998.1 AEO67429.1 - 9.1 6.4 8.8 16 5.6 6.1 1.6 1 1 0 1 1 1 0 Transcription Regulator MHYT PF03707.11 AEO67430.1 - 1e-10 41.5 21.4 2.4e-05 24.3 1.0 4.9 4 0 0 4 4 4 2 Bacterial signalling protein N terminal repeat PLAC8 PF04749.12 AEO67430.1 - 6.3 7.4 8.0 3.9 8.0 0.9 3.4 4 0 0 4 4 4 0 PLAC8 family Sugar_tr PF00083.19 AEO67433.1 - 2.3e-72 243.9 25.7 2.7e-72 243.7 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO67433.1 - 1.8e-23 82.8 36.6 3.2e-23 82.0 22.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_4 PF07993.7 AEO67434.1 - 6.1e-30 103.9 0.0 2.3e-29 102.0 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 AEO67434.1 - 3.9e-29 101.2 0.0 9.1e-29 100.0 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 AEO67434.1 - 8.6e-11 41.7 0.0 1.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 AEO67434.1 - 9.5e-07 28.9 0.0 2.1e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 AEO67434.1 - 0.0062 16.4 0.0 0.034 14.0 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 AEO67434.1 - 0.024 13.5 0.0 0.23 10.3 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain UreF PF01730.11 AEO67434.1 - 0.083 13.0 0.2 0.21 11.7 0.2 1.6 1 0 0 1 1 1 0 UreF Hce2 PF14856.1 AEO67435.1 - 1.9e-11 43.7 0.2 5.7e-05 22.9 0.0 2.2 1 1 1 2 2 2 2 Pathogen effector; putative necrosis-inducing factor DUF423 PF04241.10 AEO67436.1 - 6.3e-24 83.7 2.1 1.4e-23 82.6 1.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Bax1-I PF01027.15 AEO67436.1 - 0.024 14.2 1.8 0.029 13.9 1.2 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Trep_Strep PF09605.5 AEO67436.1 - 0.14 11.8 1.2 0.44 10.1 0.2 1.9 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF3325 PF11804.3 AEO67436.1 - 8.7 6.3 9.3 6 6.8 3.8 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3325) SH3BP5 PF05276.9 AEO67438.1 - 0.003 16.9 5.5 0.0033 16.7 3.8 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) TPR_MLP1_2 PF07926.7 AEO67438.1 - 0.0055 16.4 17.7 0.071 12.8 12.2 2.0 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein FUSC PF04632.7 AEO67438.1 - 0.062 11.7 6.4 0.069 11.5 4.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family LPP PF04728.8 AEO67438.1 - 0.08 12.7 0.4 0.19 11.5 0.2 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper T2SI PF02501.12 AEO67438.1 - 0.16 11.9 0.4 0.16 11.9 0.3 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein I Spc7 PF08317.6 AEO67438.1 - 0.18 10.4 11.5 0.21 10.2 8.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Mod_r PF07200.8 AEO67438.1 - 0.65 9.9 16.3 1.2 9.0 11.2 1.6 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein AAA_23 PF13476.1 AEO67438.1 - 0.92 9.8 10.1 1 9.6 7.0 1.1 1 0 0 1 1 1 0 AAA domain bZIP_2 PF07716.10 AEO67438.1 - 1.2 8.9 20.8 0.2 11.5 3.3 2.6 1 1 0 2 2 2 0 Basic region leucine zipper APG6 PF04111.7 AEO67438.1 - 2.8 6.8 12.8 3.4 6.6 8.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 AEO67438.1 - 3.6 5.3 9.0 4 5.1 6.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WXG100 PF06013.7 AEO67438.1 - 4 7.5 10.6 4.2 7.4 1.6 2.4 2 1 0 2 2 2 0 Proteins of 100 residues with WXG THOC7 PF05615.8 AEO67438.1 - 4.8 7.4 14.6 24 5.1 0.2 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 DUF972 PF06156.8 AEO67438.1 - 4.9 7.5 15.5 30 5.0 9.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF342 PF03961.8 AEO67438.1 - 5.9 5.1 9.7 7.1 4.9 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2196 PF09962.4 AEO67439.1 - 1.4e-23 82.3 0.7 2.4e-23 81.6 0.5 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) TOBE_2 PF08402.5 AEO67439.1 - 0.0098 15.8 0.2 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 TOBE domain COX1 PF00115.15 AEO67440.1 - 0.63 8.5 10.0 0.23 10.0 3.3 2.0 1 1 1 2 2 2 0 Cytochrome C and Quinol oxidase polypeptide I Amidase PF01425.16 AEO67441.1 - 2.7e-29 102.3 0.2 1.1e-28 100.2 0.1 1.8 1 1 0 1 1 1 1 Amidase PTS_EIIB PF00367.15 AEO67441.1 - 0.025 13.8 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 phosphotransferase system, EIIB MFS_1 PF07690.11 AEO67442.1 - 2.5e-40 138.2 44.5 2.5e-40 138.2 30.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO67442.1 - 2.6e-17 62.5 6.6 2.6e-17 62.5 4.6 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 AEO67442.1 - 9.3e-05 20.8 14.5 9.3e-05 20.8 10.1 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2189 PF09955.4 AEO67442.1 - 0.0026 17.6 0.0 0.0026 17.6 0.0 4.9 4 1 0 5 5 5 1 Predicted integral membrane protein (DUF2189) TM_helix PF05552.7 AEO67442.1 - 0.73 9.5 6.2 12 5.6 0.0 3.6 3 0 0 3 3 3 0 Conserved TM helix NB-ARC PF00931.17 AEO67445.1 - 4.7e-09 35.5 0.0 4.6e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 AEO67445.1 - 5.3e-06 26.2 0.3 0.00015 21.6 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Polyoma_agno PF01736.11 AEO67445.1 - 0.013 15.0 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Polyomavirus agnoprotein AAA_22 PF13401.1 AEO67445.1 - 0.02 15.0 0.0 0.081 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.12 AEO67445.1 - 0.035 14.0 0.1 0.16 11.9 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO67445.1 - 0.049 13.2 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat CorA PF01544.13 AEO67446.1 - 1.4e-07 30.8 0.0 2.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein GMC_oxred_N PF00732.14 AEO67447.1 - 3e-47 161.2 0.0 3.8e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO67447.1 - 6.8e-32 110.7 0.1 1.2e-31 109.9 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 AEO67447.1 - 0.0055 15.6 0.0 0.22 10.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 AEO67447.1 - 0.057 12.3 0.1 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 AEO67447.1 - 0.062 13.3 0.1 0.21 11.6 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 AEO67447.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 AEO67447.1 - 0.14 11.9 0.0 0.44 10.3 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 AEO67447.1 - 0.17 10.4 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Glyco_transf_54 PF04666.8 AEO67452.1 - 0.035 12.8 0.0 1.2 7.7 0.0 2.3 2 1 0 2 2 2 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DIM PF08194.7 AEO67453.1 - 8.6 6.4 7.1 30 4.6 0.1 3.2 3 0 0 3 3 3 0 DIM protein p450 PF00067.17 AEO67454.1 - 3.5e-53 180.7 0.0 4.2e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 AEO67455.1 - 8.7e-05 22.3 8.8 0.00015 21.5 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO67455.1 - 0.00019 20.1 2.6 0.00027 19.6 1.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hemerythrin PF01814.18 AEO67456.1 - 4.1e-17 62.5 0.1 6.7e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF1031 PF06275.6 AEO67456.1 - 0.027 14.4 0.1 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Glyco_hydro_10 PF00331.15 AEO67457.1 - 3.1e-103 345.1 0.0 3.7e-103 344.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 AEO67457.1 - 6.1e-15 54.5 12.0 1.6e-14 53.1 8.3 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Herpes_capsid PF06112.6 AEO67457.1 - 1.3 9.0 7.2 2.8 7.9 5.0 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Sporozoite_P67 PF05642.6 AEO67457.1 - 2.1 6.0 10.7 4.1 5.1 7.4 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen DNA_binding_1 PF01035.15 AEO67458.1 - 0.29 10.9 0.0 0.29 10.9 0.0 2.5 3 0 0 3 3 3 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Conotoxin PF02950.12 AEO67459.1 - 0.44 11.3 5.0 0.13 13.0 1.1 1.8 2 0 0 2 2 2 0 Conotoxin Cutinase PF01083.17 AEO67461.1 - 1.3e-52 178.1 10.3 1.6e-52 177.8 7.2 1.1 1 0 0 1 1 1 1 Cutinase CBM_1 PF00734.13 AEO67461.1 - 1.9e-10 40.2 18.6 1.9e-10 40.2 12.9 5.1 6 1 1 7 7 7 1 Fungal cellulose binding domain PE-PPE PF08237.6 AEO67461.1 - 4.6e-06 26.2 0.2 7.1e-06 25.5 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.2 AEO67461.1 - 0.00061 19.7 0.0 0.00074 19.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO67461.1 - 0.0013 18.2 0.1 0.004 16.7 0.1 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Toxin_7 PF05980.7 AEO67461.1 - 0.0016 18.4 6.4 0.0016 18.4 4.4 2.7 2 0 0 2 2 2 1 Toxin 7 VirJ PF06057.6 AEO67461.1 - 0.022 14.5 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DHDPS PF00701.17 AEO67463.1 - 7.3e-25 87.1 0.0 9.6e-25 86.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF818 PF05677.7 AEO67463.1 - 0.2 10.3 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Isochorismatase PF00857.15 AEO67464.1 - 4.4e-24 85.3 0.0 5.1e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family NUDIX_4 PF14815.1 AEO67465.1 - 1.1e-16 60.3 0.0 3.1e-16 58.7 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.20 AEO67465.1 - 1.7e-12 47.5 0.0 4.8e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 AEO67465.1 - 0.00059 19.4 0.1 0.002 17.7 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 AEO67465.1 - 0.0092 16.1 0.1 0.092 12.9 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain AIM24 PF01987.12 AEO67466.1 - 2.9e-48 164.1 0.0 3.7e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 AEO67466.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) Kinesin PF00225.18 AEO67467.1 - 1.5e-82 276.9 0.1 2.6e-82 276.2 0.0 1.4 2 0 0 2 2 2 1 Kinesin motor domain HHH_3 PF12836.2 AEO67467.1 - 0.099 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif TFIIA PF03153.8 AEO67467.1 - 0.19 11.5 14.8 0.34 10.7 10.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC_membrane PF00664.18 AEO67468.1 - 1.5e-37 129.4 13.4 1.9e-37 129.1 9.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 AEO67468.1 - 1.4e-31 109.5 0.0 2.4e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 AEO67468.1 - 7e-07 29.4 0.0 3.4e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 AEO67468.1 - 1.7e-05 24.1 0.0 0.0075 15.5 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AEO67468.1 - 8e-05 22.7 0.0 0.095 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 AEO67468.1 - 0.00017 21.7 0.0 0.0029 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AEO67468.1 - 0.00018 21.3 0.0 0.0017 18.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AEO67468.1 - 0.00024 21.9 0.0 0.00047 20.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AEO67468.1 - 0.00058 19.0 0.0 0.0014 17.7 0.0 1.6 2 0 0 2 2 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 AEO67468.1 - 0.0022 17.4 0.0 0.0098 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 AEO67468.1 - 0.0026 17.2 0.0 0.0066 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 AEO67468.1 - 0.0038 16.6 0.0 0.012 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 AEO67468.1 - 0.0048 16.8 0.0 0.016 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 AEO67468.1 - 0.0055 16.9 0.0 0.049 13.8 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 AEO67468.1 - 0.014 15.2 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 AEO67468.1 - 0.025 14.5 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 AEO67468.1 - 0.026 14.8 0.0 0.083 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain MobB PF03205.9 AEO67468.1 - 0.031 13.9 0.0 0.076 12.7 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 AEO67468.1 - 0.033 14.6 0.0 0.096 13.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Zeta_toxin PF06414.7 AEO67468.1 - 0.046 12.8 0.0 0.14 11.2 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 AEO67468.1 - 0.048 13.3 0.1 0.2 11.2 0.0 2.1 3 0 0 3 3 3 0 NACHT domain DUF87 PF01935.12 AEO67468.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 AEO67468.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 AEO67468.1 - 0.089 12.7 0.4 0.69 9.8 0.3 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.1 AEO67468.1 - 0.13 11.7 0.3 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 AEO67468.1 - 0.16 10.5 0.1 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MFS_1 PF07690.11 AEO67469.1 - 9.2e-29 100.2 26.0 9.2e-29 100.2 18.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO67469.1 - 9.7e-12 44.1 20.8 8e-11 41.1 14.2 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter FAD_binding_3 PF01494.14 AEO67470.1 - 4e-22 78.7 0.0 7.2e-22 77.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.6 AEO67470.1 - 8.4e-11 41.6 0.1 3e-10 39.8 0.1 1.7 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) DAO PF01266.19 AEO67470.1 - 7.9e-08 31.5 1.0 1.5e-07 30.6 0.3 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO67470.1 - 1.2e-07 31.5 0.2 2.8e-07 30.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 AEO67470.1 - 3.7e-06 26.0 1.0 7.3e-06 25.0 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AEO67470.1 - 7.6e-06 25.9 0.1 1.5e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO67470.1 - 5.7e-05 23.4 0.2 0.00017 21.9 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 AEO67470.1 - 5.9e-05 22.3 0.5 0.21 10.6 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 AEO67470.1 - 0.00016 20.4 0.1 0.0026 16.4 0.1 2.4 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.9 AEO67470.1 - 0.00061 18.3 0.1 0.00093 17.7 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 AEO67470.1 - 0.00089 18.2 0.3 0.0013 17.7 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 AEO67470.1 - 0.0012 17.8 0.4 0.77 8.6 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein ApbA PF02558.11 AEO67470.1 - 0.002 17.5 0.3 0.0037 16.7 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 AEO67470.1 - 0.0025 17.4 0.1 0.0045 16.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 AEO67470.1 - 0.0025 16.9 0.0 0.0043 16.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 AEO67470.1 - 0.007 15.4 0.2 0.012 14.7 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF1344 PF07076.6 AEO67470.1 - 0.032 13.8 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Pyr_redox_3 PF13738.1 AEO67470.1 - 0.041 13.9 0.1 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO67470.1 - 0.07 12.9 0.4 0.3 10.8 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 AEO67470.1 - 0.083 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 AEO67470.1 - 0.087 12.4 0.1 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 AEO67470.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Zn_clus PF00172.13 AEO67471.1 - 1.2e-06 28.3 8.4 1.2e-06 28.3 5.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 AEO67471.1 - 0.035 14.4 2.2 0.083 13.2 0.7 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type LigB PF02900.13 AEO67472.1 - 2.7e-24 85.6 0.1 3.3e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Peptidase_S15 PF02129.13 AEO67473.1 - 5.4e-43 147.3 0.7 7.3e-43 146.9 0.5 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 AEO67473.1 - 7.7e-41 140.3 1.4 1.2e-40 139.7 1.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 AEO67473.1 - 6.4e-06 26.2 0.2 1.8e-05 24.7 0.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO67473.1 - 0.0008 19.1 0.3 0.0023 17.6 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Amidase PF01425.16 AEO67473.1 - 0.01 14.7 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 0 Amidase Hydrolase_4 PF12146.3 AEO67473.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase FAA_hydrolase PF01557.13 AEO67474.1 - 2.1e-48 164.6 0.1 2.9e-48 164.2 0.1 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 AEO67474.1 - 2.1e-16 59.8 0.0 1.1e-15 57.5 0.0 2.0 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Cupin_2 PF07883.6 AEO67475.1 - 1.7e-09 37.0 0.0 5.1e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 AEO67475.1 - 0.016 14.5 0.0 0.05 12.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Aldedh PF00171.17 AEO67476.1 - 1.4e-16 59.9 0.0 8e-16 57.4 0.0 2.0 2 1 0 2 2 2 1 Aldehyde dehydrogenase family DUF1996 PF09362.5 AEO67479.1 - 1.3e-85 286.8 5.2 1.3e-85 286.8 1.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Sporozoite_P67 PF05642.6 AEO67480.1 - 0.45 8.3 3.2 0.44 8.3 2.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CorA PF01544.13 AEO67484.1 - 3.9e-06 26.1 0.1 5.5e-06 25.6 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein E1-E2_ATPase PF00122.15 AEO67487.1 - 3.9e-59 199.4 0.9 8.4e-59 198.3 0.7 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AEO67487.1 - 6.3e-43 146.4 4.0 6.3e-43 146.4 2.8 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AEO67487.1 - 2.2e-28 100.1 0.0 1.5e-27 97.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO67487.1 - 1.7e-18 66.3 0.0 3.3e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AEO67487.1 - 3.3e-15 56.7 0.0 7.5e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AEO67487.1 - 7.9e-09 34.8 0.3 3.8e-08 32.6 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AEO67487.1 - 5e-07 29.5 0.3 4.3e-05 23.2 0.2 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase GMC_oxred_N PF00732.14 AEO67488.1 - 1.6e-50 171.9 0.0 4.1e-50 170.6 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO67488.1 - 5.6e-36 123.9 0.0 1.1e-35 123.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 AEO67488.1 - 1.1e-09 37.6 0.0 3.9e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO67488.1 - 6.2e-09 35.1 5.6 0.00027 19.8 3.6 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 AEO67488.1 - 2.9e-06 27.4 0.1 0.024 14.6 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO67488.1 - 8.2e-05 22.5 1.7 0.00025 20.9 1.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AEO67488.1 - 0.00018 21.4 0.1 0.00045 20.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO67488.1 - 0.0037 16.3 4.8 0.02 14.0 3.4 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO67488.1 - 0.0055 17.0 2.8 0.061 13.7 1.6 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO67488.1 - 0.0074 14.7 1.9 0.012 14.0 1.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 AEO67488.1 - 0.011 14.6 1.1 0.024 13.5 0.7 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 AEO67488.1 - 0.039 12.9 1.8 0.067 12.2 0.9 1.6 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 AEO67488.1 - 0.16 11.0 0.4 0.32 10.0 0.3 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 AEO67488.1 - 0.32 9.7 5.8 0.58 8.9 2.3 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A CTD PF12815.2 AEO67490.1 - 0.034 14.5 0.3 0.041 14.3 0.2 1.2 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 XFP_N PF09364.5 AEO67491.1 - 7.1e-148 492.1 0.0 9.5e-148 491.7 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 AEO67491.1 - 9.4e-70 233.8 0.0 1.4e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 AEO67491.1 - 9.2e-60 201.5 0.0 1.4e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 AEO67491.1 - 0.0014 18.2 0.2 0.0099 15.4 0.1 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fungal_trans_2 PF11951.3 AEO67492.1 - 0.0004 19.0 0.1 0.00062 18.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 AEO67493.1 - 1.7e-37 129.0 0.7 2.3e-37 128.6 0.5 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF2678 PF10856.3 AEO67493.1 - 0.037 13.7 0.2 0.13 11.9 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) DUF3040 PF11239.3 AEO67493.1 - 2.9 8.0 9.9 11 6.0 0.3 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) BNR PF02012.15 AEO67494.1 - 0.0039 16.7 7.7 0.47 10.4 0.1 3.6 3 0 0 3 3 3 2 BNR/Asp-box repeat COG5 PF10392.4 AEO67495.1 - 9.1e-32 109.7 0.6 2.6e-31 108.2 0.0 2.0 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF2434 PF10361.4 AEO67496.1 - 2.9e-131 436.9 7.7 3.8e-131 436.5 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) zf-C2H2_4 PF13894.1 AEO67497.1 - 3.2e-06 27.0 12.7 0.00058 20.0 1.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO67497.1 - 6.4e-06 26.1 4.0 6.4e-06 26.1 2.8 3.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 AEO67497.1 - 1.4e-05 25.1 11.4 0.0065 16.7 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Ecl1 PF12855.2 AEO67498.1 - 0.72 9.1 4.8 1.9 7.8 3.4 1.7 1 1 0 1 1 1 0 Life-span regulatory factor zf-MYND PF01753.13 AEO67498.1 - 0.95 9.3 6.4 2 8.3 4.4 1.6 1 0 0 1 1 1 0 MYND finger Colipase PF01114.13 AEO67499.1 - 0.0072 15.7 4.2 0.012 15.0 2.9 1.3 1 0 0 1 1 1 1 Colipase, N-terminal domain Gamma-thionin PF00304.15 AEO67499.1 - 1.1 9.3 7.4 1.5 8.9 5.1 1.3 1 0 0 1 1 1 0 Gamma-thionin family MR_MLE_C PF13378.1 AEO67500.1 - 3.9e-36 123.3 0.7 8e-36 122.3 0.2 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 AEO67500.1 - 6.6e-16 58.3 0.0 1.3e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 AEO67500.1 - 3.8e-09 36.9 0.0 1.2e-08 35.3 0.0 1.9 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain p450 PF00067.17 AEO67502.1 - 2.3e-70 237.4 0.0 3e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 AEO67503.1 - 1.5e-16 60.4 0.0 2e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SNARE_assoc PF09335.6 AEO67504.1 - 8.7e-18 64.7 9.8 2.4e-17 63.2 6.2 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein WBP-1 PF11669.3 AEO67504.1 - 0.0054 16.7 0.8 0.63 10.1 0.0 2.7 2 0 0 2 2 2 1 WW domain-binding protein 1 DUF1469 PF07332.6 AEO67504.1 - 0.0067 16.1 12.0 0.11 12.2 1.1 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF1469) FtsL PF04999.8 AEO67504.1 - 0.1 12.3 0.3 21 4.9 0.0 2.7 2 0 0 2 2 2 0 Cell division protein FtsL DUF3278 PF11683.3 AEO67504.1 - 0.17 11.9 0.1 0.17 11.9 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) DUF3671 PF12420.3 AEO67504.1 - 0.29 11.1 11.6 2.1 8.3 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function CFEM PF05730.6 AEO67508.1 - 2.7e-12 46.3 10.6 5.3e-12 45.3 7.4 1.5 1 0 0 1 1 1 1 CFEM domain DUF1857 PF08982.6 AEO67509.1 - 1.5e-35 121.9 0.0 1.9e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) DUF4535 PF15054.1 AEO67509.1 - 0.15 11.4 0.1 0.15 11.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) MFS_1 PF07690.11 AEO67511.1 - 7.7e-32 110.3 19.8 7.7e-32 110.3 13.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_3 PF00933.16 AEO67512.1 - 2.7e-58 197.3 0.0 4.2e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO67512.1 - 1.1e-50 172.3 0.2 1.5e-50 171.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain WSC PF01822.14 AEO67512.1 - 1.4e-16 60.1 6.2 3.1e-16 59.0 4.3 1.6 1 0 0 1 1 1 1 WSC domain Fn3-like PF14310.1 AEO67512.1 - 2e-07 30.8 0.0 7.8e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF3866 PF12982.2 AEO67512.1 - 0.18 10.7 0.3 0.3 10.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) Zn_clus PF00172.13 AEO67514.1 - 1.3e-08 34.6 10.4 2.5e-08 33.7 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO67514.1 - 0.0038 15.8 0.1 0.0049 15.5 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 AEO67517.1 - 2.7e-24 85.5 64.1 3.9e-20 71.8 26.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Omptin PF01278.15 AEO67517.1 - 0.025 13.6 0.0 2.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Omptin family Tenui_NS4 PF03300.8 AEO67517.1 - 0.24 10.4 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Tenuivirus non-structural protein NS4 Ribonuclease_T2 PF00445.13 AEO67518.1 - 9.8e-40 136.1 1.3 2e-39 135.1 0.9 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family DUF538 PF04398.7 AEO67518.1 - 0.054 13.7 0.1 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF538 DUF2628 PF10947.3 AEO67519.1 - 0.59 9.9 5.6 1 9.2 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) OPA3 PF07047.7 AEO67520.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) RVT_1 PF00078.22 AEO67521.1 - 0.0073 15.6 0.4 0.0073 15.6 0.3 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EI24 PF07264.6 AEO67524.1 - 6.2e-06 25.8 0.9 6.2e-06 25.8 0.6 2.1 2 0 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) DUF805 PF05656.9 AEO67524.1 - 3 7.6 9.5 2.4 7.9 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF805) DUF2417 PF10329.4 AEO67524.1 - 7.2 5.9 8.1 4.7 6.5 4.0 1.8 2 0 0 2 2 2 0 Region of unknown function (DUF2417) GMC_oxred_N PF00732.14 AEO67525.1 - 1.9e-55 188.1 0.0 3.5e-55 187.2 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO67525.1 - 1.3e-40 138.9 0.0 2.1e-40 138.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 AEO67525.1 - 1.9e-07 30.2 0.0 0.0023 16.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 AEO67525.1 - 0.00018 20.5 0.4 0.0018 17.2 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO67525.1 - 0.00068 19.6 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 AEO67525.1 - 0.00098 18.1 1.5 0.0012 17.8 0.4 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 AEO67525.1 - 0.0021 17.1 0.1 0.0032 16.5 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 AEO67525.1 - 0.039 13.8 0.0 0.094 12.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 AEO67525.1 - 0.27 9.8 0.2 0.39 9.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MFS_1 PF07690.11 AEO67526.1 - 1.5e-42 145.6 44.1 1.5e-42 145.6 30.6 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2919 PF11143.3 AEO67526.1 - 0.034 13.9 2.5 0.059 13.1 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) Phage_holin_2 PF04550.7 AEO67526.1 - 1.9 8.6 6.0 0.6 10.2 1.1 2.4 2 0 0 2 2 2 0 Phage holin family 2 SecE PF00584.15 AEO67526.1 - 9.9 5.8 8.5 0.97 9.0 1.5 2.7 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex GFA PF04828.9 AEO67527.1 - 9.1e-13 47.9 0.1 9.1e-13 47.9 0.0 1.4 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 AEO67527.1 - 0.01 15.5 0.4 0.01 15.5 0.3 2.4 3 0 0 3 3 3 0 Nudix N-terminal YiaAB PF05360.9 AEO67527.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 yiaA/B two helix domain Cys_rich_CWC PF14375.1 AEO67527.1 - 1.8 8.5 8.2 0.14 12.0 2.5 1.6 2 0 0 2 2 2 0 Cysteine-rich CWC 2-Hacid_dh_C PF02826.14 AEO67528.1 - 9.6e-43 145.3 0.0 1.2e-28 99.4 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 AEO67528.1 - 0.00047 20.2 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 AEO67528.1 - 0.0019 18.5 0.0 0.014 15.8 0.0 2.5 4 0 0 4 4 4 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 AEO67528.1 - 0.04 13.7 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 AEO67528.1 - 0.074 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AEO67528.1 - 0.089 12.2 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 AEO67528.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.7 1 1 0 1 1 1 0 XdhC Rossmann domain NACHT PF05729.7 AEO67529.1 - 3.1e-10 39.9 0.0 1.3e-09 37.9 0.0 2.1 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 AEO67529.1 - 9.4e-07 29.0 0.6 8.9e-05 22.6 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_10 PF12846.2 AEO67529.1 - 0.0018 17.8 0.3 0.045 13.1 0.0 2.8 3 0 0 3 3 3 1 AAA-like domain ABC_tran PF00005.22 AEO67529.1 - 0.0024 18.1 0.0 0.012 15.8 0.0 2.2 2 1 0 2 2 2 1 ABC transporter AAA_17 PF13207.1 AEO67529.1 - 0.0066 17.2 0.0 0.029 15.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 AEO67529.1 - 0.011 15.2 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 AEO67529.1 - 0.014 15.7 0.0 0.046 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Vps39_1 PF10366.4 AEO67529.1 - 0.02 14.8 0.4 0.049 13.6 0.3 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 RNA_helicase PF00910.17 AEO67529.1 - 0.035 14.2 0.1 0.31 11.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 AEO67529.1 - 0.047 13.8 0.0 0.47 10.6 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 AEO67529.1 - 0.076 12.7 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 NTPase Arch_ATPase PF01637.13 AEO67529.1 - 0.096 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 AEO67529.1 - 0.11 11.3 0.0 0.29 9.9 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.1 AEO67529.1 - 0.2 11.9 0.2 1.5 9.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain PPDK_N PF01326.14 AEO67530.1 - 1.9e-88 296.6 0.0 3.6e-88 295.7 0.0 1.4 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.13 AEO67530.1 - 3.2e-61 206.7 0.0 5.3e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.18 AEO67530.1 - 1.5e-24 85.3 1.2 4.6e-24 83.7 0.9 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Ldh_1_N PF00056.18 AEO67531.1 - 2.6e-26 92.1 0.2 3.7e-26 91.6 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 AEO67531.1 - 1.1e-24 87.0 0.0 1.6e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ThiF PF00899.16 AEO67531.1 - 0.00019 21.2 0.4 0.00033 20.4 0.3 1.5 1 0 0 1 1 1 1 ThiF family F420_oxidored PF03807.12 AEO67531.1 - 0.002 18.5 0.7 0.0059 17.0 0.5 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Malic_M PF03949.10 AEO67531.1 - 0.0039 16.7 0.0 0.0085 15.6 0.0 1.6 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain Glyco_hydro_4 PF02056.11 AEO67531.1 - 0.0047 16.2 0.1 0.013 14.8 0.0 1.6 1 1 0 1 1 1 1 Family 4 glycosyl hydrolase Glyoxalase_2 PF12681.2 AEO67534.1 - 3e-08 34.2 0.1 3.9e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AEO67534.1 - 0.00015 21.7 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2580 PF10824.3 AEO67534.1 - 1.3 9.4 5.6 0.66 10.3 2.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2580) RVT_2 PF07727.9 AEO67535.1 - 2.5e-12 46.2 2.6 2.7e-12 46.1 1.8 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.7 AEO67538.1 - 0.15 9.9 12.1 0.25 9.2 8.4 1.3 1 0 0 1 1 1 0 Nop14-like family PBP_sp32 PF07222.7 AEO67538.1 - 0.16 11.1 4.1 0.28 10.3 2.9 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pox_Ag35 PF03286.9 AEO67538.1 - 0.68 9.4 19.2 0.021 14.3 6.5 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF3246 PF11596.3 AEO67538.1 - 1.6 7.9 4.7 0.22 10.7 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) PBP1_TM PF14812.1 AEO67538.1 - 2.8 8.3 26.8 0.19 12.0 3.2 3.0 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC27 PF09507.5 AEO67538.1 - 2.8 7.0 25.2 0.31 10.2 7.2 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 PGA2 PF07543.7 AEO67538.1 - 5.1 6.8 14.9 2.3 7.9 8.1 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 Asp PF00026.18 AEO67539.1 - 1.5e-60 205.1 3.3 2e-60 204.6 2.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO67539.1 - 3.7e-11 43.2 2.6 4.7e-11 42.9 0.1 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 AEO67539.1 - 1.1e-05 25.1 0.0 0.0047 16.7 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 AEO67539.1 - 0.0028 18.0 0.8 6.3 7.3 0.2 3.3 2 1 0 2 2 2 2 Aspartyl protease Saccharop_dh PF03435.13 AEO67542.1 - 1.8e-97 326.7 0.0 2.2e-97 326.4 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 AEO67542.1 - 1.9e-05 24.7 0.3 3.3e-05 23.9 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF2325 PF10087.4 AEO67542.1 - 0.1 12.4 0.1 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Glyco_hydro_28 PF00295.12 AEO67543.1 - 2.5e-89 299.4 5.2 5.6e-89 298.3 3.6 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectinesterase PF01095.14 AEO67543.1 - 7.8e-41 139.5 1.2 7.8e-41 139.5 0.8 2.3 3 0 0 3 3 3 1 Pectinesterase Beta_helix PF13229.1 AEO67543.1 - 0.55 9.9 38.4 0.012 15.3 15.5 4.0 2 1 1 3 3 3 0 Right handed beta helix region zf-CCHC PF00098.18 AEO67545.1 - 1.3e-13 50.1 15.4 5.5e-05 22.8 0.2 3.4 3 0 0 3 3 3 3 Zinc knuckle Retrotrans_gag PF03732.12 AEO67545.1 - 2.4e-07 30.7 0.0 4.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_4 PF14392.1 AEO67545.1 - 4.3e-05 23.0 12.4 0.11 12.1 0.3 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.1 AEO67545.1 - 0.15 11.7 7.7 0.49 10.1 0.6 3.3 2 1 1 3 3 3 0 Zinc knuckle UBN2 PF14223.1 AEO67545.1 - 0.2 11.4 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RNA_pol_N PF01194.12 AEO67545.1 - 0.39 10.7 4.8 0.34 10.9 0.7 2.4 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit zf-CCHC_2 PF13696.1 AEO67545.1 - 1.7 8.2 13.7 0.94 9.0 1.3 3.7 2 1 1 3 3 3 0 Zinc knuckle Prothymosin PF03247.9 AEO67546.1 - 0.037 14.1 9.2 0.048 13.8 6.4 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family CENP-B_dimeris PF09026.5 AEO67546.1 - 0.12 12.5 3.4 0.19 12.0 2.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DTHCT PF08070.6 AEO67546.1 - 0.22 12.2 5.5 0.18 12.5 3.0 1.4 1 1 0 1 1 1 0 DTHCT (NUC029) region Spore_coat_CotO PF14153.1 AEO67546.1 - 0.32 10.3 2.7 0.36 10.2 1.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Nucleoplasmin PF03066.10 AEO67546.1 - 0.48 9.9 5.7 0.54 9.7 4.0 1.1 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 AEO67546.1 - 0.93 9.0 7.0 0.97 9.0 4.8 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 AEO67546.1 - 1.1 9.6 8.8 1.6 9.0 6.1 1.5 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3716 PF12511.3 AEO67547.1 - 2.1e-14 52.8 4.1 2.7e-14 52.4 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Cytochrome_C7 PF14522.1 AEO67547.1 - 0.013 15.1 1.8 0.018 14.6 1.3 1.2 1 0 0 1 1 1 0 Cytochrome c7 BTB PF00651.26 AEO67548.1 - 1.3e-13 50.9 0.0 2.4e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain GFA PF04828.9 AEO67549.1 - 1.6e-07 31.1 2.3 1.6e-07 31.1 1.6 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_2 PF00891.13 AEO67550.1 - 1.6e-08 34.0 0.0 4e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase Glyco_transf_20 PF00982.16 AEO67551.1 - 7.5e-150 499.5 0.0 1e-149 499.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 AEO67551.1 - 6.4e-72 241.2 0.0 1.2e-71 240.3 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_trans_1_4 PF13692.1 AEO67551.1 - 0.026 14.6 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 MFS_1 PF07690.11 AEO67552.1 - 3.5e-23 81.8 30.6 2.8e-12 46.0 9.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO67552.1 - 1.1e-06 27.5 6.9 1.9e-06 26.7 4.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 AEO67552.1 - 1.2e-06 27.2 17.1 0.0017 16.8 3.5 3.0 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 AEO67552.1 - 0.12 12.1 12.0 0.5 10.2 0.4 3.1 3 0 0 3 3 3 0 MFS_1 like family OATP PF03137.15 AEO67552.1 - 0.14 10.1 1.5 0.29 9.1 0.4 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.14 AEO67553.1 - 8.5e-15 54.6 0.3 2.7e-14 53.0 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain Cys_Met_Meta_PP PF01053.15 AEO67554.1 - 1.1e-26 93.0 0.0 6.5e-26 90.5 0.0 2.2 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 AEO67554.1 - 0.17 10.8 0.0 1.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class I and II PI3K_1B_p101 PF10486.4 AEO67555.1 - 0.81 7.1 1.5 1.2 6.6 1.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4229 PF14012.1 AEO67556.1 - 0.097 12.5 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Mito_carr PF00153.22 AEO67557.1 - 1.8e-54 181.3 3.7 1.1e-21 76.3 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DND1_DSRM PF14709.1 AEO67557.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 TruB-C_2 PF09157.6 AEO67558.1 - 0.12 12.2 0.3 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal DUF2370 PF10176.4 AEO67559.1 - 2.2e-84 282.4 0.0 3.9e-84 281.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 AEO67559.1 - 0.089 13.0 0.2 0.49 10.6 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) PCMT PF01135.14 AEO67560.1 - 1.6e-49 168.3 0.0 1.9e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 AEO67560.1 - 1.6e-05 25.4 0.0 2.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO67560.1 - 2.6e-05 23.9 0.0 3.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO67560.1 - 0.00033 20.6 0.1 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO67560.1 - 0.00053 19.5 0.0 0.00094 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 AEO67560.1 - 0.0016 18.0 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FAD_binding_3 PF01494.14 AEO67561.1 - 4e-08 32.7 0.4 3e-07 29.8 0.3 2.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 AEO67561.1 - 5.3e-07 29.9 0.1 4e-05 23.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AEO67561.1 - 2.6e-06 26.6 2.9 2.4e-05 23.3 0.0 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO67561.1 - 1.3e-05 25.0 0.0 4.1e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 AEO67561.1 - 0.0011 17.8 0.3 0.0019 17.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AEO67561.1 - 0.0019 18.0 0.3 0.0045 16.8 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO67561.1 - 0.002 17.2 1.9 0.0028 16.7 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.11 AEO67561.1 - 0.0075 15.7 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 AEO67561.1 - 0.0079 15.1 0.3 0.011 14.5 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 AEO67561.1 - 0.0094 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 AEO67561.1 - 0.011 15.8 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 AEO67561.1 - 0.15 11.5 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 AEO67561.1 - 0.22 9.9 0.1 0.31 9.4 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans PF04082.13 AEO67562.1 - 7.1e-16 57.8 0.1 1.1e-15 57.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO67562.1 - 1.1e-08 34.7 13.6 1.1e-08 34.7 9.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos PF00149.23 AEO67564.1 - 0.0001 21.7 0.1 0.00019 20.8 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AEO67564.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF2204 PF09970.4 AEO67565.1 - 0.0016 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) ADH_N PF08240.7 AEO67566.1 - 0.32 10.7 5.7 1.4 8.6 0.9 2.9 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain AAA_13 PF13166.1 AEO67569.1 - 0.0011 17.5 64.6 0.035 12.5 10.8 3.7 1 1 3 4 4 4 4 AAA domain Myosin_tail_1 PF01576.14 AEO67569.1 - 0.3 8.7 92.2 0.091 10.4 2.3 2.8 2 1 0 2 2 2 0 Myosin tail DAO PF01266.19 AEO67570.1 - 2.3e-41 141.9 6.8 2.8e-41 141.6 4.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.21 AEO67570.1 - 1.9e-13 49.7 0.1 4.5e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.1 AEO67570.1 - 1.3e-07 31.4 1.5 3.5e-07 30.1 1.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 AEO67570.1 - 6e-06 25.5 6.2 0.00014 21.0 4.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO67570.1 - 2.2e-05 23.5 0.7 4.1e-05 22.6 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AEO67570.1 - 3.5e-05 23.7 0.2 0.0001 22.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AEO67570.1 - 8.7e-05 21.5 1.8 0.00012 21.0 0.7 1.6 1 1 1 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 AEO67570.1 - 0.00012 21.2 0.0 0.00022 20.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 AEO67570.1 - 0.00029 19.9 1.7 0.00065 18.8 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 AEO67570.1 - 0.00039 19.0 0.1 0.00054 18.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 AEO67570.1 - 0.00042 20.6 0.2 0.0014 19.0 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO67570.1 - 0.00083 19.4 0.3 0.0083 16.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO67570.1 - 0.0014 17.6 1.4 0.002 17.1 0.2 1.8 2 1 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.13 AEO67570.1 - 0.0048 16.5 0.2 0.0084 15.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 AEO67570.1 - 0.0073 15.4 1.8 0.014 14.5 0.5 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 AEO67570.1 - 0.072 12.8 0.1 0.56 9.9 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NCU-G1 PF15065.1 AEO67572.1 - 0.0044 15.7 0.6 0.0044 15.7 0.4 1.8 2 0 0 2 2 2 1 Lysosomal transcription factor, NCU-G1 Mid2 PF04478.7 AEO67572.1 - 0.011 15.1 0.0 0.029 13.8 0.0 1.7 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.5 AEO67572.1 - 0.33 10.3 3.0 1 8.7 2.1 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3042 PF11240.3 AEO67572.1 - 2.9 7.7 7.3 1.2 8.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) DUF1996 PF09362.5 AEO67575.1 - 1.2e-81 273.8 3.5 1.4e-81 273.5 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Tyrosinase PF00264.15 AEO67576.1 - 1.4e-25 90.7 0.0 2.8e-25 89.8 0.0 1.4 1 1 0 1 1 1 1 Common central domain of tyrosinase Fructosamin_kin PF03881.9 AEO67577.1 - 2.1e-48 164.8 0.0 2.4e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 AEO67577.1 - 5.5e-05 23.0 0.0 0.00031 20.5 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 AEO67577.1 - 0.00049 19.3 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Aldo_ket_red PF00248.16 AEO67578.1 - 1.6e-17 63.2 0.0 2e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 AEO67579.1 - 4e-20 71.8 0.0 6.2e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family PGAP1 PF07819.8 AEO67579.1 - 9.2e-08 31.9 0.0 1.8e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein WD40 PF00400.27 AEO67579.1 - 4.2e-05 23.2 0.1 0.11 12.4 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat Abhydrolase_5 PF12695.2 AEO67579.1 - 0.00018 21.2 2.2 0.00031 20.5 0.1 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 AEO67579.1 - 0.00076 18.8 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.1 AEO67579.1 - 0.0079 16.3 0.1 0.44 10.6 0.0 3.2 2 1 1 3 3 3 1 AAA domain Abhydrolase_1 PF00561.15 AEO67579.1 - 0.021 14.3 0.1 0.062 12.8 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 AEO67579.1 - 0.021 14.4 0.0 0.055 13.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.10 AEO67579.1 - 0.026 13.5 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase NACHT PF05729.7 AEO67579.1 - 0.029 14.0 0.1 0.074 12.7 0.1 1.7 1 0 0 1 1 1 0 NACHT domain DUF3312 PF11768.3 AEO67579.1 - 0.094 10.9 0.0 0.15 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Cutinase PF01083.17 AEO67579.1 - 0.13 11.9 0.0 0.39 10.4 0.0 1.7 2 0 0 2 2 2 0 Cutinase DUF2974 PF11187.3 AEO67579.1 - 0.25 10.6 0.0 0.46 9.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) MMS1_N PF10433.4 AEO67579.1 - 0.3 9.1 0.0 0.57 8.2 0.0 1.3 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Pectate_lyase_3 PF12708.2 AEO67580.1 - 1.2e-29 104.0 5.9 3e-18 66.7 2.6 2.9 2 1 0 2 2 2 2 Pectate lyase superfamily protein Beta_helix PF13229.1 AEO67580.1 - 0.00025 20.8 5.5 0.00046 19.9 3.4 1.7 1 1 0 1 1 1 1 Right handed beta helix region CDP-OH_P_tran_2 PF08009.6 AEO67581.1 - 5.8 6.7 9.4 0.75 9.5 0.6 2.7 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 Pkinase PF00069.20 AEO67582.1 - 1e-26 93.6 0.0 1.3e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO67582.1 - 0.0016 17.6 0.1 0.013 14.5 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO67582.1 - 0.0022 17.7 1.5 2.6 7.7 0.0 2.9 2 1 0 3 3 3 2 Phosphotransferase enzyme family OprB PF04966.7 AEO67583.1 - 0.064 12.3 0.3 0.084 11.9 0.2 1.1 1 0 0 1 1 1 0 Carbohydrate-selective porin, OprB family Sugar_tr PF00083.19 AEO67584.1 - 6.7e-67 226.0 27.1 7.7e-67 225.8 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO67584.1 - 1.5e-10 40.3 37.8 1.5e-10 40.3 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO67584.1 - 0.043 12.2 28.0 0.044 12.1 9.5 2.9 2 1 0 2 2 2 0 MFS/sugar transport protein adh_short_C2 PF13561.1 AEO67585.1 - 0.0013 18.5 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AflR PF08493.5 AEO67586.1 - 3.3e-17 62.4 5.5 3.3e-17 62.4 3.8 2.3 1 1 1 2 2 2 1 Aflatoxin regulatory protein DUF605 PF04652.11 AEO67586.1 - 9.1 5.5 14.0 14 4.9 9.7 1.2 1 0 0 1 1 1 0 Vta1 like RPE65 PF03055.10 AEO67587.1 - 4e-126 421.4 0.0 4.6e-126 421.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SnoaL_4 PF13577.1 AEO67588.1 - 3.1e-15 56.2 0.5 4.1e-15 55.8 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain RNase_H PF00075.19 AEO67590.1 - 9.7e-05 22.7 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 RNase H Molybdopterin PF00384.17 AEO67593.1 - 4.5e-69 233.2 0.0 6.6e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.16 AEO67593.1 - 4.1e-26 90.9 0.0 9.2e-26 89.8 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.11 AEO67593.1 - 4.1e-13 48.9 0.3 1e-12 47.6 0.2 1.7 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain MoeA_N PF03453.12 AEO67594.1 - 1.4e-35 122.0 0.3 2.3e-35 121.3 0.2 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.19 AEO67594.1 - 1.3e-26 92.7 0.0 1.9e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.10 AEO67594.1 - 0.017 15.0 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 MoeA C-terminal region (domain IV) DMRL_synthase PF00885.14 AEO67594.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase NTP_transf_3 PF12804.2 AEO67595.1 - 2.8e-26 92.5 2.3 7.5e-26 91.1 1.6 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain DUF605 PF04652.11 AEO67595.1 - 5.8 6.2 7.5 6.7 5.9 5.2 1.0 1 0 0 1 1 1 0 Vta1 like DUF3237 PF11578.3 AEO67596.1 - 2.3e-38 130.8 0.0 3.5e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Fungal_trans PF04082.13 AEO67597.1 - 1e-05 24.5 0.1 2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain YjeF_N PF03853.10 AEO67598.1 - 0.11 12.0 0.1 0.43 10.1 0.0 1.8 1 1 1 2 2 2 0 YjeF-related protein N-terminus Pyr_redox_2 PF07992.9 AEO67599.1 - 0.00015 21.6 0.0 0.0024 17.7 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO67599.1 - 0.00095 19.2 0.1 0.0074 16.3 0.1 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO67599.1 - 0.0015 18.2 0.0 0.017 14.9 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 AEO67599.1 - 0.0027 16.6 0.0 0.0049 15.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Malic_M PF03949.10 AEO67599.1 - 0.046 13.2 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Epimerase PF01370.16 AEO67600.1 - 6.5e-17 61.7 0.0 2.3e-16 59.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO67600.1 - 5.7e-11 42.7 0.2 1.4e-10 41.4 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 AEO67600.1 - 1e-10 41.0 0.0 1.6e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 AEO67600.1 - 6.1e-08 31.7 0.0 1.4e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 AEO67600.1 - 2.6e-05 24.1 3.2 6.4e-05 22.9 0.1 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO67600.1 - 0.0024 17.5 0.6 0.0052 16.4 0.1 1.9 2 0 0 2 2 2 1 KR domain NmrA PF05368.8 AEO67600.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Pkinase PF00069.20 AEO67602.1 - 0.0062 15.7 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Clr5 PF14420.1 AEO67604.1 - 9.5e-10 38.2 0.1 9.5e-10 38.2 0.1 1.7 2 0 0 2 2 2 1 Clr5 domain Abhydrolase_6 PF12697.2 AEO67605.1 - 1e-25 90.9 0.1 1.2e-25 90.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO67605.1 - 1.1e-15 57.8 0.1 1.6e-14 54.0 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO67605.1 - 2.1e-08 34.0 0.0 4.7e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 AEO67605.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3328 PF11807.3 AEO67606.1 - 1.7e-33 116.1 4.0 2e-33 115.9 2.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) AA_permease_2 PF13520.1 AEO67607.1 - 5.5e-48 163.5 53.3 6.9e-48 163.2 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO67607.1 - 1.2e-21 76.6 48.8 2.7e-21 75.4 33.9 1.5 1 1 0 1 1 1 1 Amino acid permease Abhydrolase_5 PF12695.2 AEO67608.1 - 1.3e-15 57.4 0.0 2e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 AEO67608.1 - 2.3e-10 39.3 0.0 0.00016 20.0 0.0 2.6 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 AEO67608.1 - 2.6e-09 37.2 2.0 4.5e-09 36.5 1.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 AEO67608.1 - 0.00026 19.9 0.0 0.00068 18.6 0.0 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.20 AEO67608.1 - 0.0077 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 AEO67608.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.8 AEO67608.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Zn_clus PF00172.13 AEO67609.1 - 9.8e-06 25.3 7.4 9.8e-06 25.3 5.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 AEO67610.1 - 2.7e-21 75.4 0.0 4.9e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO67610.1 - 8.9e-08 33.0 0.0 1.7e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-LITAF-like PF10601.4 AEO67611.1 - 2.9e-22 78.3 5.0 3.7e-22 77.9 3.5 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain NOB1_Zn_bind PF08772.6 AEO67611.1 - 1.4 8.7 6.9 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like FAD_binding_3 PF01494.14 AEO67613.1 - 1e-45 156.3 0.0 1.4e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO67613.1 - 0.00014 20.8 0.0 0.067 12.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO67613.1 - 0.0004 20.3 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 AEO67613.1 - 0.0017 17.4 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 AEO67613.1 - 0.0034 15.9 0.0 0.0056 15.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 AEO67613.1 - 0.029 14.7 0.0 3.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO67613.1 - 0.033 13.1 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 AEO67613.1 - 0.035 14.1 0.0 0.14 12.2 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SH3_3 PF08239.6 AEO67613.1 - 0.041 14.0 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain FAD_binding_2 PF00890.19 AEO67613.1 - 0.092 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 AEO67613.1 - 0.093 11.5 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pkinase_Tyr PF07714.12 AEO67614.1 - 2.4e-18 66.1 0.0 9.4e-18 64.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 AEO67614.1 - 4e-17 62.2 0.0 5.4e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 AEO67614.1 - 0.00079 18.5 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Caleosin PF05042.8 AEO67615.1 - 2.3e-54 183.5 0.0 2.9e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.1 AEO67615.1 - 0.00026 20.5 0.3 0.45 10.5 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 AEO67615.1 - 0.0013 17.8 0.0 1.7 8.1 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 AEO67615.1 - 0.0033 17.5 0.0 0.41 10.8 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 AEO67615.1 - 0.044 13.1 0.1 20 4.7 0.0 3.3 3 0 0 3 3 3 0 EF hand Glyco_hydro_2 PF00703.16 AEO67616.1 - 9.4e-10 38.9 0.0 2.1e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 AEO67616.1 - 1.9e-06 27.5 0.1 4.8e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain ADH_zinc_N PF00107.21 AEO67617.1 - 1.8e-32 111.6 0.4 2.7e-32 111.0 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO67617.1 - 2.6e-15 57.4 0.1 7.1e-15 56.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO67617.1 - 1e-12 47.7 0.0 2.2e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 AEO67617.1 - 0.00031 20.7 0.0 0.00077 19.4 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 AEO67617.1 - 0.0016 17.9 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_kinase PF01513.16 AEO67617.1 - 0.042 12.6 0.1 0.059 12.1 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase ELFV_dehydrog PF00208.16 AEO67617.1 - 0.056 13.0 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Aminotran_1_2 PF00155.16 AEO67617.1 - 0.12 11.3 0.0 3.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Aminotransferase class I and II CLAMP PF14769.1 AEO67617.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 SE PF08491.5 AEO67618.1 - 1e-80 270.5 0.0 1.3e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 AEO67618.1 - 3.1e-09 36.3 0.4 1.9e-08 33.8 0.3 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO67618.1 - 1.4e-08 34.0 2.0 6e-07 28.6 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO67618.1 - 8.7e-08 31.4 1.2 4.1e-05 22.6 1.7 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 AEO67618.1 - 2.9e-07 29.7 1.5 0.004 16.1 0.3 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.17 AEO67618.1 - 1.2e-05 24.4 0.3 0.0011 17.9 1.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 AEO67618.1 - 9.4e-05 22.3 0.9 0.00026 20.9 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 AEO67618.1 - 0.00019 20.6 3.4 0.00034 19.8 2.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO67618.1 - 0.00023 21.4 0.4 0.0005 20.4 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 AEO67618.1 - 0.00031 20.4 0.2 0.00054 19.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 AEO67618.1 - 0.001 19.1 0.3 0.0029 17.6 0.1 1.8 2 0 0 2 2 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 AEO67618.1 - 0.0011 18.9 0.0 0.0056 16.5 0.4 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 AEO67618.1 - 0.0016 16.8 0.0 0.0023 16.3 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Thi4 PF01946.12 AEO67618.1 - 0.0017 17.4 0.1 0.0044 16.1 0.0 1.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 AEO67618.1 - 0.0065 14.9 0.1 0.0099 14.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 AEO67618.1 - 0.017 13.7 0.1 0.057 12.0 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase ThiF PF00899.16 AEO67618.1 - 0.052 13.3 0.1 0.094 12.5 0.1 1.3 1 0 0 1 1 1 0 ThiF family ApbA PF02558.11 AEO67618.1 - 0.066 12.6 0.2 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 AEO67618.1 - 0.084 12.6 0.1 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.1 AEO67618.1 - 0.1 12.6 0.2 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3938 PF13074.1 AEO67619.1 - 0.0076 16.0 0.5 0.017 14.9 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3938) Abhydrolase_6 PF12697.2 AEO67620.1 - 3.1e-14 53.3 0.0 5.2e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO67620.1 - 2.9e-07 30.3 0.0 6.2e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO67620.1 - 0.046 12.9 0.0 0.47 9.6 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family ADP_ribosyl_GH PF03747.9 AEO67621.1 - 1.1e-13 51.6 0.1 1.2e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase ADP_ribosyl_GH PF03747.9 AEO67622.1 - 3.4e-29 102.5 1.3 4.7e-29 102.0 0.9 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase FKBP_N PF01346.13 AEO67622.1 - 0.097 12.7 0.4 0.16 12.0 0.3 1.3 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase CC PF04942.9 AEO67623.1 - 0.0064 16.3 1.5 0.0064 16.3 1.0 3.9 4 0 0 4 4 4 1 CC domain DUF2678 PF10856.3 AEO67623.1 - 0.11 12.2 0.1 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) Phosphoprotein PF00922.12 AEO67623.1 - 1.5 7.9 5.0 2.5 7.2 3.4 1.3 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein DAP10 PF07213.6 AEO67623.1 - 5.7 6.7 10.1 0.32 10.7 1.2 2.9 2 1 1 3 3 3 0 DAP10 membrane protein p450 PF00067.17 AEO67625.1 - 9.3e-49 166.1 0.0 3.1e-48 164.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 PCI_Csn8 PF10075.4 AEO67626.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 HTH_3 PF01381.17 AEO67626.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix MIP-T3 PF10243.4 AEO67627.1 - 0.12 10.7 33.4 0.18 10.2 23.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Aminotran_3 PF00202.16 AEO67628.1 - 6.8e-55 186.2 0.0 1e-54 185.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III SSP160 PF06933.6 AEO67632.1 - 0.01 13.8 1.3 0.015 13.3 0.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Trypan_PARP PF05887.6 AEO67633.1 - 0.41 10.4 5.9 0.64 9.8 4.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Herpes_capsid PF06112.6 AEO67633.1 - 9.8 6.2 9.0 13 5.8 6.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein WD40 PF00400.27 AEO67635.1 - 8e-12 44.5 8.3 0.0015 18.2 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat GRAM PF02893.15 AEO67636.1 - 6e-26 89.7 0.0 1.3e-14 53.4 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 AEO67636.1 - 1.2e-25 89.8 0.0 2.7e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 AEO67636.1 - 5.6e-12 45.7 0.0 1.3e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 AEO67636.1 - 2.7e-05 24.1 0.1 6.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 AEO67636.1 - 0.00013 21.8 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 AEO67636.1 - 0.0002 21.6 1.9 0.0023 18.1 1.3 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.13 AEO67636.1 - 0.012 14.2 0.0 0.025 13.1 0.0 1.4 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase PH_9 PF15410.1 AEO67636.1 - 0.035 14.2 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain NIF PF03031.13 AEO67637.1 - 3.8e-29 101.3 0.1 1e-28 99.9 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 AEO67637.1 - 1.2e-05 25.0 0.0 3.1e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 AEO67637.1 - 0.0006 19.9 0.0 0.0016 18.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl PF00364.17 AEO67637.1 - 0.011 15.3 0.1 0.53 9.9 0.0 3.0 3 0 0 3 3 3 0 Biotin-requiring enzyme GRIM-19 PF06212.7 AEO67638.1 - 2.1e-22 79.1 0.0 4.1e-22 78.2 0.0 1.4 1 1 0 1 1 1 1 GRIM-19 protein DUF4283 PF14111.1 AEO67638.1 - 0.087 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) TGF_beta_GS PF08515.7 AEO67639.1 - 0.21 10.9 2.5 0.57 9.5 1.7 1.6 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Cnd1_N PF12922.2 AEO67640.1 - 7e-61 204.7 0.1 7e-61 204.7 0.1 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 AEO67640.1 - 7.7e-56 188.7 1.1 1.3e-52 178.2 0.2 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 AEO67640.1 - 8.4e-11 42.0 6.8 2.3e-05 24.5 0.0 6.5 5 3 0 5 5 5 2 HEAT repeats HEAT PF02985.17 AEO67640.1 - 1.3e-08 34.2 13.0 0.042 13.9 0.0 7.2 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.1 AEO67640.1 - 8e-07 29.3 5.3 0.012 16.0 0.1 5.7 5 0 0 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.15 AEO67640.1 - 0.00013 20.4 3.7 0.0077 14.5 0.2 3.6 3 1 0 3 3 3 2 Adaptin N terminal region DUF2435 PF10363.4 AEO67640.1 - 0.00074 19.3 0.0 0.83 9.5 0.0 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF2435) Cnd3 PF12719.2 AEO67640.1 - 0.0021 17.1 3.2 0.0046 16.0 0.2 3.1 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Ald_Xan_dh_C2 PF02738.13 AEO67640.1 - 0.025 12.9 0.0 0.04 12.2 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase Cohesin_HEAT PF12765.2 AEO67640.1 - 0.06 13.3 0.0 6.7 6.7 0.0 3.5 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Pkinase PF00069.20 AEO67641.1 - 7.9e-41 139.9 0.0 1.8e-37 128.8 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO67641.1 - 6.9e-13 48.2 0.0 1.3e-06 27.7 0.0 3.8 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.18 AEO67641.1 - 8e-05 22.4 0.1 0.013 15.2 0.0 2.9 2 2 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 AEO67641.1 - 0.0011 17.9 0.0 0.057 12.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like ResIII PF04851.10 AEO67642.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 AEO67642.1 - 1.8 8.3 4.7 22 4.9 3.3 2.3 1 1 0 1 1 1 0 Part of AAA domain Helicase_C_2 PF13307.1 AEO67643.1 - 1.4e-57 194.2 0.0 2.3e-57 193.5 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain SUZ PF12752.2 AEO67643.1 - 0.16 12.4 1.6 0.74 10.3 1.1 2.1 1 0 0 1 1 1 0 SUZ domain zf-DBF PF07535.7 AEO67644.1 - 0.098 12.3 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 DBF zinc finger FAD_binding_3 PF01494.14 AEO67645.1 - 2.7e-17 62.8 2.4 1e-09 37.9 0.3 2.7 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 AEO67645.1 - 1.3e-05 25.0 0.1 5.3e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 AEO67645.1 - 0.00018 21.3 0.1 0.00041 20.1 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 AEO67645.1 - 0.0032 16.3 0.0 0.0051 15.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO67645.1 - 0.0054 15.6 0.6 0.034 13.0 0.0 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AEO67645.1 - 0.0095 16.0 0.1 0.02 14.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO67645.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO67645.1 - 0.029 12.8 0.1 0.044 12.2 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 AEO67645.1 - 0.04 12.5 0.1 0.06 11.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.7 AEO67645.1 - 0.043 12.7 0.1 0.072 11.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 AEO67645.1 - 0.068 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 AEO67645.1 - 0.14 12.5 0.0 0.46 10.9 0.0 1.9 2 1 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AEO67645.1 - 0.22 10.3 0.2 0.29 9.9 0.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Macoilin PF09726.4 AEO67647.1 - 0.23 9.7 0.7 0.29 9.3 0.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Gly-zipper_OmpA PF13436.1 AEO67647.1 - 0.35 10.5 16.9 0.83 9.3 11.7 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain PAT1 PF09770.4 AEO67647.1 - 3.6 5.6 14.4 4.6 5.3 10.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Bestrophin PF01062.16 AEO67648.1 - 1.5 7.6 6.7 1 8.2 1.0 2.2 1 1 1 2 2 2 0 Bestrophin, RFP-TM, chloride channel SET PF00856.23 AEO67650.1 - 1e-14 55.1 0.1 2.7e-13 50.5 0.0 2.1 1 1 0 1 1 1 1 SET domain Aa_trans PF01490.13 AEO67651.1 - 4e-22 78.2 29.3 2.1e-21 75.9 20.3 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein F-box PF00646.28 AEO67652.1 - 0.0026 17.3 0.3 0.0053 16.3 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 AEO67652.1 - 0.0044 16.7 0.1 0.0091 15.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like SNAPc19 PF15497.1 AEO67654.1 - 0.056 13.6 0.3 0.26 11.5 0.0 2.3 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Allexi_40kDa PF05549.6 AEO67654.1 - 0.25 10.6 3.5 9.4 5.4 1.5 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein Ribosomal_60s PF00428.14 AEO67656.1 - 0.05 13.9 5.4 0.11 12.9 3.8 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3375 PF11855.3 AEO67656.1 - 0.063 12.0 0.1 0.15 10.7 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3375) Herpes_DNAp_acc PF04929.7 AEO67656.1 - 0.32 9.9 2.6 0.41 9.5 1.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Sigma70_ner PF04546.8 AEO67656.1 - 0.46 10.0 5.5 6.3 6.3 4.1 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region PRCC PF10253.4 AEO67658.1 - 5.3 7.6 20.1 8.1 7.0 4.8 2.5 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Nop14 PF04147.7 AEO67658.1 - 5.7 4.7 13.7 10 3.9 9.5 1.3 1 0 0 1 1 1 0 Nop14-like family CTP_transf_2 PF01467.21 AEO67659.1 - 3.2e-06 27.2 0.0 1.6e-05 25.0 0.0 2.1 2 1 0 2 2 2 1 Cytidylyltransferase Mito_carr PF00153.22 AEO67660.1 - 1e-16 60.3 4.4 1.7e-11 43.7 0.2 4.2 4 0 0 4 4 4 3 Mitochondrial carrier protein NPP1 PF05630.6 AEO67661.1 - 9.1e-79 263.9 0.7 1.1e-78 263.7 0.5 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF946 PF06101.6 AEO67661.1 - 0.0047 14.9 0.4 0.0065 14.5 0.3 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) PepSY_2 PF13670.1 AEO67661.1 - 4 7.4 6.0 3.6 7.5 1.6 2.5 2 1 0 2 2 2 0 Peptidase propeptide and YPEB domain Glyco_hydro_61 PF03443.9 AEO67662.1 - 1.4e-54 185.2 0.0 1.7e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 AEO67662.1 - 0.02 14.9 0.0 1.8 8.6 0.0 2.7 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase SH3_3 PF08239.6 AEO67662.1 - 0.069 13.3 1.9 1 9.6 0.6 2.6 2 1 0 2 2 2 0 Bacterial SH3 domain MFS_1 PF07690.11 AEO67664.1 - 3.9e-09 35.6 5.7 3.9e-09 35.6 4.0 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO67664.1 - 7.8e-07 28.0 2.2 1.7e-06 26.8 1.5 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 AEO67664.1 - 0.00086 17.8 7.0 0.022 13.1 0.4 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein Fructosamin_kin PF03881.9 AEO67665.1 - 1.7e-32 112.5 0.0 2.2e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase NACHT PF05729.7 AEO67667.1 - 1.6e-06 27.9 0.1 3.5e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.27 AEO67667.1 - 3.6e-06 26.6 4.8 0.036 13.9 0.1 5.2 4 1 1 5 5 5 2 WD domain, G-beta repeat AAA_16 PF13191.1 AEO67667.1 - 2.2e-05 24.5 0.4 0.00012 22.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AEO67667.1 - 0.00036 20.6 0.0 0.0011 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO67667.1 - 0.0013 18.4 0.0 0.0048 16.6 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 AEO67667.1 - 0.0048 15.8 0.0 0.018 13.9 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_17 PF13207.1 AEO67667.1 - 0.0093 16.7 0.0 0.046 14.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AEO67667.1 - 0.011 15.6 0.2 0.037 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 AEO67667.1 - 0.015 15.4 0.0 0.049 13.8 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 AEO67667.1 - 0.049 13.0 0.0 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 AEO67667.1 - 0.31 9.7 0.0 0.82 8.3 0.0 1.6 1 0 0 1 1 1 0 ArgK protein DUF2697 PF10906.3 AEO67668.1 - 0.0011 18.8 0.1 0.0016 18.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2697) AAA_16 PF13191.1 AEO67669.1 - 2.3e-08 34.2 1.1 1.8e-07 31.3 0.0 3.1 4 0 0 4 4 4 1 AAA ATPase domain RrnaAD PF00398.15 AEO67669.1 - 3.3e-05 23.0 0.0 0.00015 20.8 0.0 2.1 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase AAA_22 PF13401.1 AEO67669.1 - 0.00025 21.2 0.0 0.0009 19.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 AEO67669.1 - 0.00098 18.8 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 AEO67669.1 - 0.051 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 AEO67669.1 - 0.077 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Arteri_nucleo PF01481.11 AEO67669.1 - 0.18 11.8 0.0 8.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Arterivirus nucleocapsid protein Rad17 PF03215.10 AEO67669.1 - 0.61 8.6 0.0 0.96 8.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Glyco_transf_90 PF05686.7 AEO67670.1 - 8.1e-12 44.5 0.1 1.9e-06 26.8 0.0 3.4 3 0 0 3 3 3 3 Glycosyl transferase family 90 SR-25 PF10500.4 AEO67670.1 - 9.7 5.5 13.8 21 4.5 9.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Arginase PF00491.16 AEO67671.1 - 3.5e-77 259.4 0.3 4.2e-77 259.1 0.2 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.18 AEO67672.1 - 2e-07 30.9 15.9 2.8e-07 30.4 11.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain HTH_28 PF13518.1 AEO67673.1 - 0.011 15.6 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.1 AEO67673.1 - 0.076 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Pyocin_S PF06958.7 AEO67673.1 - 0.16 12.3 2.6 0.32 11.3 1.8 1.5 1 0 0 1 1 1 0 S-type Pyocin Microtub_assoc PF07989.6 AEO67674.1 - 1.3e-19 69.7 8.4 1.3e-19 69.7 5.9 8.9 7 2 1 10 10 10 1 Microtubule associated Mto2_bdg PF12808.2 AEO67674.1 - 1.8e-10 40.7 16.1 1.8e-10 40.7 11.2 14.0 14 3 1 15 15 15 2 Micro-tubular organiser Mto1 C-term Mto2-binding region DegS PF05384.6 AEO67674.1 - 0.00043 19.5 2.3 0.00043 19.5 1.6 8.7 4 1 4 9 9 9 1 Sensor protein DegS IncA PF04156.9 AEO67674.1 - 0.005 16.4 20.2 0.005 16.4 14.0 9.4 4 2 3 8 8 8 3 IncA protein NPV_P10 PF05531.7 AEO67674.1 - 0.061 13.5 0.1 0.061 13.5 0.1 6.9 5 1 0 6 6 6 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 AEO67674.1 - 0.092 11.9 37.2 0.014 14.5 3.2 5.3 5 1 1 6 6 6 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 AEO67674.1 - 0.37 10.9 68.9 0.22 11.6 2.3 7.4 4 2 3 7 7 7 0 Fibrinogen alpha/beta chain family Sec7 PF01369.15 AEO67675.1 - 1.2e-43 149.0 0.0 2.3e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 AEO67675.1 - 1.4e-16 60.6 0.0 3.6e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain adh_short PF00106.20 AEO67676.1 - 0.00049 20.0 0.1 0.0036 17.2 0.0 2.2 1 1 1 2 2 2 1 short chain dehydrogenase DUF4331 PF14224.1 AEO67676.1 - 0.0098 15.0 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4331) adh_short PF00106.20 AEO67680.1 - 2.1e-24 86.2 4.8 1.1e-23 83.9 3.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO67680.1 - 1.9e-10 40.9 0.1 3.2e-10 40.2 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO67680.1 - 1.3e-08 34.6 1.3 2.4e-08 33.8 0.9 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO67680.1 - 0.00024 20.5 0.3 0.00049 19.5 0.2 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_8 PF13450.1 AEO67680.1 - 0.019 15.0 0.2 0.038 14.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_trans_4_4 PF13579.1 AEO67680.1 - 0.082 13.0 1.1 0.14 12.3 0.8 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Thi4 PF01946.12 AEO67680.1 - 0.099 11.7 1.0 0.19 10.7 0.4 1.7 2 0 0 2 2 2 0 Thi4 family Eno-Rase_NADH_b PF12242.3 AEO67680.1 - 0.39 10.5 5.3 0.45 10.3 0.8 2.8 2 1 1 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 AEO67680.1 - 0.43 10.5 5.2 3.3 7.6 3.0 2.5 2 1 0 2 2 2 0 NADH(P)-binding Sel1 PF08238.7 AEO67681.1 - 3.5e-21 75.1 24.3 6.9e-08 32.8 0.1 7.3 7 0 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.23 AEO67681.1 - 0.04 13.5 2.4 0.092 12.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 AEO67681.1 - 0.18 11.4 2.8 0.92 9.2 0.0 2.9 3 0 0 3 3 3 0 TPR repeat TPR_6 PF13174.1 AEO67681.1 - 9.1 6.9 7.7 7.4 7.2 0.0 4.1 5 1 0 5 5 5 0 Tetratricopeptide repeat Metallophos PF00149.23 AEO67682.1 - 9.8e-12 44.6 0.1 1.6e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SAC3_GANP PF03399.11 AEO67683.1 - 2.9e-22 79.2 0.0 4e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 AEO67683.1 - 1.8e-18 66.7 0.0 2.7e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Coatomer_WDAD PF04053.9 AEO67684.1 - 3.5e-148 494.0 0.0 5e-148 493.5 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 AEO67684.1 - 7.5e-88 294.8 0.0 1.1e-87 294.4 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 AEO67684.1 - 1.3e-49 164.3 11.9 1.6e-09 37.2 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 AEO67684.1 - 0.0017 16.6 9.3 0.2 9.7 0.1 4.0 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Clathrin PF00637.15 AEO67684.1 - 0.11 12.1 0.7 0.5 9.9 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS UDP-g_GGTase PF06427.6 AEO67685.1 - 6e-62 208.6 0.0 4.5e-60 202.5 0.0 2.3 2 0 0 2 2 2 2 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 AEO67685.1 - 0.00034 20.0 1.2 0.00091 18.6 0.8 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 SNF2_N PF00176.18 AEO67686.1 - 6.6e-69 231.9 0.0 8.9e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 AEO67686.1 - 2.8e-64 216.5 1.8 1e-63 214.6 1.6 1.7 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 AEO67686.1 - 4.2e-13 48.9 0.0 1.5e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 AEO67686.1 - 6.8e-06 25.1 0.0 2.2e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 AEO67686.1 - 0.00075 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Citrate_ly_lig PF08218.6 AEO67686.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain AAA_22 PF13401.1 AEO67686.1 - 0.083 13.0 0.1 0.76 9.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain Mito_carr PF00153.22 AEO67687.1 - 1.5e-46 155.9 2.6 2.3e-20 72.1 0.2 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein NYN PF01936.13 AEO67688.1 - 0.055 13.7 0.0 0.31 11.3 0.0 2.1 1 1 0 1 1 1 0 NYN domain CD24 PF14984.1 AEO67689.1 - 7 6.5 6.4 3.9 7.3 0.2 2.1 2 0 0 2 2 2 0 CD24 protein Bromodomain PF00439.20 AEO67690.1 - 1.1e-43 147.0 0.6 1.1e-21 76.5 0.2 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 AEO67690.1 - 9.5e-18 64.0 0.3 2e-17 63.0 0.2 1.6 1 0 0 1 1 1 1 BAH domain Sigma70_ner PF04546.8 AEO67690.1 - 0.0053 16.4 7.1 0.0053 16.4 4.9 4.0 4 0 0 4 4 4 1 Sigma-70, non-essential region AT_hook PF02178.14 AEO67690.1 - 3.6 7.5 13.8 0.17 11.6 0.7 3.3 2 0 0 2 2 2 0 AT hook motif OTU PF02338.14 AEO67691.1 - 7.4e-08 33.0 0.0 1.4e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.3 AEO67691.1 - 0.026 14.8 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 FmdA_AmdA PF03069.10 AEO67692.1 - 8.7e-154 511.6 0.0 1e-153 511.4 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family EI24 PF07264.6 AEO67693.1 - 5.3e-07 29.2 8.4 3.9e-06 26.4 5.8 2.0 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.2 AEO67694.1 - 2.6e-36 124.4 0.0 6.4e-36 123.1 0.0 1.7 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 CBS PF00571.23 AEO67695.1 - 1.4e-18 66.4 2.7 0.00022 20.9 0.1 5.3 5 0 0 5 5 5 5 CBS domain HEAT_2 PF13646.1 AEO67696.1 - 9.7e-25 86.6 21.0 1.6e-09 37.9 0.2 8.3 2 2 8 10 10 10 9 HEAT repeats HEAT PF02985.17 AEO67696.1 - 5.3e-22 75.8 22.0 0.0013 18.6 0.0 12.0 13 0 0 13 13 11 6 HEAT repeat HEAT_EZ PF13513.1 AEO67696.1 - 3.8e-18 65.4 25.3 1.9e-08 34.5 0.1 11.2 7 2 7 14 14 13 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 AEO67696.1 - 3.4e-13 49.7 0.2 0.012 15.9 0.0 7.4 3 2 5 8 8 8 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 AEO67696.1 - 7.2e-10 38.1 0.2 4.1e-06 25.7 0.0 4.1 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal RIX1 PF08167.7 AEO67696.1 - 4.7e-09 36.1 0.0 0.0043 16.7 0.0 5.4 4 1 1 5 5 5 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 AEO67696.1 - 1.3e-07 31.1 1.9 0.066 12.5 0.0 6.2 5 2 2 7 7 7 1 CLASP N terminal Adaptin_N PF01602.15 AEO67696.1 - 1.8e-06 26.6 2.3 0.0045 15.3 0.1 4.7 4 1 1 5 5 5 1 Adaptin N terminal region Xpo1 PF08389.7 AEO67696.1 - 1.1e-05 25.3 1.1 0.00089 19.1 0.1 3.8 3 2 1 4 4 3 1 Exportin 1-like protein Proteasom_PSMB PF10508.4 AEO67696.1 - 0.00025 19.4 0.0 0.012 13.9 0.0 2.9 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit DUF4042 PF13251.1 AEO67696.1 - 0.0003 20.3 0.0 3.6 7.0 0.0 4.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4042) Arm PF00514.18 AEO67696.1 - 0.00041 20.0 15.1 0.084 12.7 0.0 6.3 8 0 0 8 8 7 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 AEO67696.1 - 0.0059 16.4 0.1 0.1 12.5 0.0 3.4 2 1 0 2 2 2 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.10 AEO67696.1 - 0.013 13.8 1.2 0.6 8.3 0.0 3.7 5 0 0 5 5 5 0 CAS/CSE protein, C-terminus Sec23_helical PF04815.10 AEO67696.1 - 0.022 14.1 0.6 0.85 9.0 0.0 3.2 3 0 0 3 3 3 0 Sec23/Sec24 helical domain TFCD_C PF12612.3 AEO67696.1 - 0.03 13.7 1.8 0.93 8.8 0.0 3.7 3 2 0 3 3 3 0 Tubulin folding cofactor D C terminal UME PF08064.8 AEO67696.1 - 0.043 13.7 0.1 19 5.2 0.0 4.5 4 1 1 5 5 5 0 UME (NUC010) domain Dopey_N PF04118.9 AEO67696.1 - 0.19 10.4 1.2 1.3 7.7 0.0 2.8 3 1 1 4 4 4 0 Dopey, N-terminal PAS_9 PF13426.1 AEO67697.1 - 2.4e-27 95.3 0.0 2.6e-18 66.2 0.0 3.3 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 AEO67697.1 - 1.1e-18 67.0 0.0 1e-11 44.7 0.0 3.3 3 0 0 3 3 3 3 PAS fold GATA PF00320.22 AEO67697.1 - 1.6e-14 52.9 3.2 3.1e-14 52.0 2.2 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 AEO67697.1 - 1.5e-12 47.3 0.0 2.7e-05 23.9 0.0 3.6 3 1 0 3 3 3 3 PAS fold PAS_4 PF08448.5 AEO67697.1 - 3.7e-08 33.3 0.0 0.11 12.5 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.1 AEO67697.1 - 1.9e-06 27.8 0.0 0.02 14.8 0.0 2.5 2 0 0 2 2 2 2 PAS domain RTA1 PF04479.8 AEO67699.1 - 1.5e-17 63.8 1.6 3.5e-17 62.6 1.1 1.5 1 1 0 1 1 1 1 RTA1 like protein Rsa3 PF14615.1 AEO67700.1 - 2.7e-22 77.7 1.3 3.6e-22 77.3 0.9 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 KfrA_N PF11740.3 AEO67700.1 - 0.074 13.4 0.5 0.092 13.1 0.4 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF2410 PF10307.4 AEO67702.1 - 1.1e-81 272.9 0.0 1.5e-81 272.5 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) zf-C2H2_jaz PF12171.3 AEO67703.1 - 1.6e-09 37.5 0.4 3e-09 36.7 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Aconitase PF00330.15 AEO67704.1 - 3.9e-170 566.3 0.0 8.7e-170 565.1 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AEO67704.1 - 2.7e-45 153.6 0.0 4.5e-45 152.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Gaa1 PF04114.9 AEO67705.1 - 1.5e-100 337.3 4.2 2.9e-100 336.3 2.9 1.5 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.17 AEO67705.1 - 5.4e-13 49.1 9.5 5.4e-13 49.1 6.6 3.1 3 1 0 3 3 3 1 Rhomboid family PCI PF01399.22 AEO67706.1 - 3.8e-09 36.8 0.0 9e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 PCI domain NmrA PF05368.8 AEO67707.1 - 3.4e-18 65.7 0.0 4.2e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO67707.1 - 1e-17 64.7 0.0 1.5e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO67707.1 - 9.3e-15 54.6 0.0 2.3e-14 53.4 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO67707.1 - 2e-09 36.5 0.0 4e-09 35.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AEO67707.1 - 2.4e-08 33.2 0.0 1.3e-06 27.4 0.0 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 AEO67707.1 - 0.0001 22.2 0.0 0.001 19.0 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 AEO67707.1 - 0.00011 21.2 0.4 0.036 12.9 0.3 3.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 AEO67707.1 - 0.0017 18.0 0.0 0.22 11.1 0.0 2.5 3 0 0 3 3 3 1 KR domain Polysacc_synt_2 PF02719.10 AEO67707.1 - 0.0022 16.9 0.0 0.0039 16.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 AEO67707.1 - 0.0056 15.6 0.0 0.0089 15.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_synthase PF02540.12 AEO67707.1 - 0.0085 15.0 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 NAD synthase DDE_Tnp_1_3 PF13612.1 AEO67707.1 - 0.059 13.1 0.0 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain NAD_binding_2 PF03446.10 AEO67707.1 - 0.089 12.6 0.0 0.45 10.3 0.0 2.1 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 AEO67707.1 - 0.15 11.4 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA N6-adenineMlase PF10237.4 AEO67708.1 - 8.4e-54 181.5 0.1 1.1e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase UCH PF00443.24 AEO67709.1 - 2.8e-56 190.6 5.5 2.8e-56 190.6 3.8 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO67709.1 - 2.8e-34 118.8 3.1 4.8e-34 118.1 2.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 AEO67709.1 - 0.0009 19.3 0.1 0.0009 19.3 0.1 2.7 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Ribosomal_L34e PF01199.13 AEO67709.1 - 0.03 14.5 0.1 0.13 12.5 0.0 2.1 1 1 1 2 2 2 0 Ribosomal protein L34e Lactamase_B PF00753.22 AEO67710.1 - 2.2e-23 82.9 3.1 3.5e-23 82.2 2.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AEO67710.1 - 2e-05 24.2 0.0 3.4e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AEO67710.1 - 0.0054 16.4 0.0 0.0076 15.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ytp1 PF10355.4 AEO67711.1 - 5.5e-114 379.9 7.4 8.3e-114 379.3 5.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 AEO67711.1 - 1.5e-33 114.5 3.5 1.5e-33 114.5 2.4 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF3481 PF11980.3 AEO67711.1 - 0.15 11.9 0.3 2.5 7.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3481) Transglut_core2 PF13369.1 AEO67712.1 - 3e-15 56.0 0.0 5.4e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 AEO67712.1 - 1.4e-08 34.3 0.9 3.5e-08 33.0 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO67712.1 - 2.5e-08 33.3 0.7 2.5e-08 33.3 0.5 2.2 2 0 0 2 2 2 1 F-box domain YccV-like PF08755.6 AEO67712.1 - 5.9e-06 26.1 0.1 2.5e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Elongin_A PF06881.6 AEO67712.1 - 0.0005 20.4 0.2 0.001 19.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A tRNA-synt_2b PF00587.20 AEO67713.1 - 2.6e-44 150.8 0.7 4.3e-44 150.1 0.5 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AEO67713.1 - 1.3e-20 73.1 0.3 2.4e-20 72.2 0.2 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 AEO67713.1 - 5.6e-12 45.3 0.0 1.4e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 AEO67713.1 - 9.3e-10 38.1 0.0 1.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain Pro-NT_NN PF07421.6 AEO67713.1 - 0.067 12.6 0.1 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor CDP-OH_P_transf PF01066.16 AEO67714.1 - 8.5e-14 51.6 1.8 1.6e-13 50.8 1.2 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Peptidase_C12 PF01088.16 AEO67715.1 - 2.1e-57 193.7 0.0 4.3e-57 192.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF1918 PF08940.6 AEO67716.1 - 0.0022 17.2 0.5 18 4.7 0.0 4.9 4 0 0 4 4 4 2 Domain of unknown function (DUF1918) I-set PF07679.11 AEO67716.1 - 0.0025 17.6 0.0 23 4.9 0.0 4.9 5 0 0 5 5 5 2 Immunoglobulin I-set domain DDE_3 PF13358.1 AEO67718.1 - 5.3e-14 52.1 1.1 6.4e-14 51.9 0.7 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HSF_DNA-bind PF00447.12 AEO67719.1 - 3.4e-38 129.9 0.2 6.5e-38 129.0 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 AEO67719.1 - 1.7e-18 66.6 0.2 3.9e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain CENP-H PF05837.7 AEO67719.1 - 0.023 14.8 6.9 0.04 14.0 4.8 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF972 PF06156.8 AEO67719.1 - 0.045 14.1 1.5 0.097 13.0 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 AEO67719.1 - 0.085 12.4 2.5 0.13 11.8 1.8 1.2 1 0 0 1 1 1 0 IncA protein W2 PF02020.13 AEO67720.1 - 1.2e-13 50.8 15.2 1.2e-13 50.8 10.5 2.7 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 AEO67720.1 - 1.9e-07 30.2 11.2 0.015 14.7 2.3 4.0 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 AEO67720.1 - 5.2e-06 25.9 0.0 8.9e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 AEO67720.1 - 0.0071 16.4 0.0 0.021 14.9 0.0 1.9 1 0 0 1 1 1 1 MobA-like NTP transferase domain Pneumo_phosprot PF02478.11 AEO67720.1 - 0.57 9.6 11.0 0.19 11.2 5.7 1.6 2 0 0 2 2 2 0 Pneumovirus phosphoprotein Hexapep_2 PF14602.1 AEO67720.1 - 2.7 7.6 7.7 6.2 6.4 0.3 3.7 3 1 2 5 5 5 0 Hexapeptide repeat of succinyl-transferase Metallopep PF12044.3 AEO67721.1 - 2.7e-164 546.6 0.0 3.6e-164 546.2 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M66 PF10462.4 AEO67721.1 - 0.14 10.9 0.7 0.63 8.8 0.3 1.9 2 0 0 2 2 2 0 Peptidase M66 Reprolysin_3 PF13582.1 AEO67721.1 - 0.15 12.6 0.4 0.38 11.2 0.2 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Whi5 PF08528.6 AEO67722.1 - 3.9e-09 35.8 0.5 7e-09 35.0 0.3 1.4 1 0 0 1 1 1 1 Whi5 like DUF885 PF05960.6 AEO67722.1 - 0.0023 17.1 0.1 0.0031 16.7 0.1 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Peptidase_C14 PF00656.17 AEO67723.1 - 5.1e-74 249.0 0.0 6.3e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 AEO67723.1 - 0.049 13.4 0.6 0.68 9.7 0.0 2.5 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Tir_receptor_N PF07490.6 AEO67723.1 - 0.16 11.5 0.8 4.5 6.8 0.1 2.1 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) N-terminus RHS_repeat PF05593.9 AEO67724.1 - 0.06 13.5 0.0 0.082 13.1 0.0 1.2 1 0 0 1 1 1 0 RHS Repeat SKG6 PF08693.5 AEO67726.1 - 0.011 15.0 2.3 0.035 13.4 1.6 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Vac14_Fig4_bd PF11916.3 AEO67728.1 - 3.8e-83 277.1 8.7 3.8e-83 277.1 6.0 1.8 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 AEO67728.1 - 4e-46 155.3 0.0 8.9e-43 144.6 0.0 4.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 AEO67728.1 - 9.4e-10 37.7 0.8 0.00011 21.9 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 AEO67728.1 - 1.5e-07 31.6 3.9 0.00067 20.0 0.1 5.5 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.1 AEO67728.1 - 1.8e-06 28.1 1.5 0.016 15.4 0.0 4.6 5 0 0 5 5 5 2 HEAT repeats Arm PF00514.18 AEO67728.1 - 0.00069 19.3 0.0 0.7 9.8 0.0 4.2 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Fiji_64_capsid PF05880.6 AEO67728.1 - 0.13 10.6 0.2 0.2 9.9 0.1 1.2 1 0 0 1 1 1 0 Fijivirus 64 kDa capsid protein RAP1 PF07218.6 AEO67729.1 - 0.94 7.4 13.5 0.97 7.4 9.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FA_desaturase PF00487.19 AEO67730.1 - 4.5e-38 131.1 26.2 4.5e-38 131.1 18.1 2.0 2 1 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 AEO67731.1 - 5.7e-08 32.4 0.0 6.6e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_dim PF02852.17 AEO67732.1 - 3.6e-39 133.1 0.0 1.2e-38 131.4 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 AEO67732.1 - 2.7e-36 125.3 16.5 1.8e-35 122.6 10.7 3.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO67732.1 - 1.8e-27 95.5 10.5 7.3e-23 80.7 0.9 3.6 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO67732.1 - 1.3e-12 47.5 2.1 2.5e-06 27.3 0.3 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AEO67732.1 - 2.5e-10 40.7 0.9 2.8e-05 24.3 0.2 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO67732.1 - 2.9e-10 39.8 5.1 1.6e-09 37.3 0.3 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO67732.1 - 6.2e-10 38.5 5.2 6.9e-07 28.4 1.9 3.3 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 AEO67732.1 - 2e-09 36.8 17.4 0.00013 20.9 1.7 4.1 3 1 0 4 4 4 3 FAD dependent oxidoreductase GIDA PF01134.17 AEO67732.1 - 1.1e-08 34.4 8.8 4.7e-07 29.0 2.2 2.9 2 2 1 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.9 AEO67732.1 - 9.1e-07 27.6 11.3 7.5e-05 21.3 1.2 4.0 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_3 PF01494.14 AEO67732.1 - 3.6e-06 26.2 6.8 0.077 12.0 0.9 3.3 3 0 0 3 3 3 3 FAD binding domain AlaDh_PNT_C PF01262.16 AEO67732.1 - 6.4e-06 25.8 1.2 0.039 13.5 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 AEO67732.1 - 8.1e-06 25.0 1.1 7.8e-05 21.8 0.0 2.3 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 AEO67732.1 - 1.4e-05 24.2 0.1 0.18 10.7 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 AEO67732.1 - 0.00032 20.8 0.8 1 9.6 0.0 2.7 2 0 0 2 2 2 2 Putative NAD(P)-binding Trp_halogenase PF04820.9 AEO67732.1 - 0.0086 14.7 3.3 0.044 12.4 0.4 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 AEO67732.1 - 0.015 14.2 3.8 0.041 12.8 0.4 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 AEO67732.1 - 0.045 12.8 0.3 8.2 5.5 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 AEO67732.1 - 0.069 12.7 0.2 0.069 12.7 0.2 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 AEO67732.1 - 0.21 10.9 3.4 2.1 7.6 0.1 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FMO-like PF00743.14 AEO67732.1 - 0.52 8.4 1.9 0.82 7.7 0.3 1.8 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like MIF4G PF02854.14 AEO67733.1 - 1.2e-20 73.7 0.0 1.3e-18 67.1 0.0 2.3 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.12 AEO67733.1 - 1.7e-14 53.4 0.1 1.5e-13 50.4 0.0 2.7 3 0 0 3 3 3 1 MA3 domain SRP14 PF02290.10 AEO67734.1 - 3.9e-27 94.0 0.0 5.5e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Tir_receptor_C PF07489.6 AEO67734.1 - 0.0094 15.7 0.3 0.013 15.2 0.2 1.2 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) C-terminus GRAM PF02893.15 AEO67734.1 - 0.06 12.8 0.1 0.094 12.2 0.1 1.3 1 0 0 1 1 1 0 GRAM domain Vps36_ESCRT-II PF11605.3 AEO67734.1 - 0.11 12.3 0.3 0.34 10.7 0.1 1.7 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 RRM_1 PF00076.17 AEO67735.1 - 9e-54 179.0 0.0 1.3e-17 63.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO67735.1 - 6.6e-43 144.5 0.0 2.1e-14 53.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO67735.1 - 4e-24 84.2 0.0 8.3e-07 28.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AEO67735.1 - 2.7e-07 30.3 0.0 0.2 11.5 0.0 3.4 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 AEO67735.1 - 1.9e-06 27.5 0.1 0.21 11.3 0.0 4.3 3 2 0 3 3 3 2 Limkain b1 ATP-grasp_2 PF08442.5 AEO67735.1 - 0.0014 18.0 0.0 0.039 13.3 0.0 2.8 3 0 0 3 3 3 1 ATP-grasp domain PknH_C PF14032.1 AEO67735.1 - 0.087 12.3 0.3 44 3.5 0.0 3.5 4 0 0 4 4 4 0 PknH-like extracellular domain GARS_A PF01071.14 AEO67735.1 - 0.14 11.6 0.0 4.9 6.6 0.1 2.8 2 1 1 3 3 3 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain THRAP3_BCLAF1 PF15440.1 AEO67735.1 - 3.8 6.0 18.5 5.4 5.5 12.9 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family COQ9 PF08511.6 AEO67736.1 - 1.9e-27 94.5 0.2 4.8e-27 93.2 0.0 1.7 2 0 0 2 2 2 1 COQ9 SMC_N PF02463.14 AEO67737.1 - 1.6e-24 86.3 6.4 1.3e-23 83.4 4.4 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AEO67737.1 - 1.1e-15 58.5 11.6 1.1e-15 58.5 8.1 4.7 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 AEO67737.1 - 1.3e-06 28.6 0.1 0.00035 20.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 AEO67737.1 - 2.2e-05 24.2 0.3 0.00011 22.0 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 AEO67737.1 - 0.00014 21.0 0.1 0.00014 21.0 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 AEO67737.1 - 0.0014 18.1 0.0 0.0033 16.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 AEO67737.1 - 0.0059 16.9 13.1 0.12 12.6 0.0 4.9 3 1 0 3 3 3 1 ABC transporter SGT1 PF07093.6 AEO67738.1 - 2.3e-152 508.4 17.1 3.3e-151 504.6 11.8 1.9 1 1 0 1 1 1 1 SGT1 protein DDHD PF02862.12 AEO67738.1 - 0.36 10.5 6.5 0.62 9.8 4.5 1.3 1 0 0 1 1 1 0 DDHD domain DUF572 PF04502.8 AEO67738.1 - 1.4 8.0 14.9 2.1 7.4 10.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DHHW PF14286.1 AEO67738.1 - 9.9 5.3 8.3 3.2 6.9 3.8 1.5 1 1 0 1 1 1 0 DHHW protein THUMP PF02926.12 AEO67740.1 - 9.2e-09 35.3 0.9 2.5e-06 27.4 0.0 2.5 3 0 0 3 3 3 2 THUMP domain Bindin PF02084.10 AEO67740.1 - 0.44 10.5 4.3 0.41 10.6 0.4 2.1 2 0 0 2 2 2 0 Bindin TPP_enzyme_N PF02776.13 AEO67741.1 - 1.9e-34 118.5 0.0 3.2e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 AEO67741.1 - 2e-29 102.0 0.0 4.1e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 AEO67741.1 - 1.6e-15 56.9 0.4 7.8e-15 54.7 0.0 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 AEO67741.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Evr1_Alr PF04777.8 AEO67742.1 - 3.8e-30 103.6 1.9 3.8e-30 103.6 1.3 1.9 2 0 0 2 2 2 1 Erv1 / Alr family Bd3614-deam PF14439.1 AEO67742.1 - 0.0069 16.2 0.3 0.66 9.8 0.1 2.1 2 0 0 2 2 2 2 Bd3614-like deaminase HEM4 PF02602.10 AEO67743.1 - 3.4e-40 137.7 0.0 4.4e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD CBM_X PF06204.6 AEO67743.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative carbohydrate binding domain TLD PF07534.11 AEO67744.1 - 3.5e-26 91.8 0.0 6.2e-15 55.4 0.0 2.2 2 0 0 2 2 2 2 TLD Pkinase PF00069.20 AEO67745.1 - 8.5e-75 251.2 0.0 1.1e-74 250.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO67745.1 - 4.8e-32 111.0 0.0 6.3e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO67745.1 - 0.00052 19.0 0.0 0.00097 18.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AEO67745.1 - 0.0022 17.0 0.1 0.0037 16.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO67745.1 - 0.014 15.1 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Gag_p6 PF08705.6 AEO67745.1 - 0.018 15.0 0.1 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Gag protein p6 Seadorna_VP7 PF07387.6 AEO67745.1 - 0.041 12.7 0.1 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 S_100 PF01023.14 AEO67745.1 - 0.062 12.6 0.2 0.22 10.8 0.2 1.9 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Sec23_trunk PF04811.10 AEO67746.1 - 1.3e-69 234.2 0.0 2.5e-69 233.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 AEO67746.1 - 3.5e-24 84.1 0.0 4.8e-23 80.5 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 AEO67746.1 - 7.3e-18 63.8 5.3 1.2e-17 63.1 3.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 AEO67746.1 - 5.9e-17 61.9 0.0 1.2e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 AEO67746.1 - 1.8e-10 40.3 0.0 3.5e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Epiglycanin_C PF14654.1 AEO67747.1 - 0.035 14.1 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region TMEMspv1-c74-12 PF11044.3 AEO67747.1 - 0.16 11.5 1.4 0.25 10.9 1.0 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein CDK2AP PF09806.4 AEO67749.1 - 0.017 15.3 0.0 0.017 15.3 0.0 2.3 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein Fungal_trans_2 PF11951.3 AEO67749.1 - 0.018 13.6 2.4 0.028 13.0 0.0 2.3 1 1 1 2 2 2 0 Fungal specific transcription factor domain Mito_fiss_reg PF05308.6 AEO67749.1 - 0.65 9.3 18.2 1.2 8.3 12.6 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Xpo1 PF08389.7 AEO67750.1 - 7.8e-07 29.1 0.1 3.3e-05 23.8 0.0 2.9 2 0 0 2 2 2 1 Exportin 1-like protein WD40 PF00400.27 AEO67751.1 - 1.4e-05 24.7 0.3 1 9.3 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF1917 PF08939.5 AEO67752.1 - 9.6e-73 244.9 0.0 1.1e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Acetyltransf_1 PF00583.19 AEO67753.1 - 1.6e-17 63.2 0.0 2.5e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AEO67753.1 - 1e-09 38.5 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO67753.1 - 2.1e-08 33.8 0.0 3.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 AEO67753.1 - 6.3e-08 32.6 0.0 9.1e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AEO67753.1 - 1.6e-07 31.5 0.0 2.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AEO67753.1 - 2.8e-05 24.0 0.0 3.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO67753.1 - 3.6e-05 23.6 0.1 5.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AEO67753.1 - 0.0016 18.3 0.0 0.0027 17.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AEO67753.1 - 0.014 15.3 0.1 0.031 14.1 0.1 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase LCAT PF02450.10 AEO67754.1 - 3.1e-96 322.7 0.0 4.2e-96 322.2 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF3673 PF12425.3 AEO67754.1 - 0.097 12.5 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) DUF2013 PF09431.5 AEO67755.1 - 8.3e-52 174.6 1.0 8.3e-52 174.6 0.7 2.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2013) Pathogen_betaC1 PF09593.5 AEO67755.1 - 0.066 12.9 0.3 0.21 11.3 0.1 1.8 2 0 0 2 2 2 0 Beta-satellite pathogenicity beta C1 protein Ribosomal_S17 PF00366.15 AEO67756.1 - 7.4e-08 32.3 0.2 1.1e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 DUF503 PF04456.7 AEO67756.1 - 0.22 11.1 1.1 12 5.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF503) AAA PF00004.24 AEO67757.1 - 2.2e-38 131.4 0.0 6.4e-38 129.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO67757.1 - 1.8e-05 24.8 0.1 0.0002 21.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO67757.1 - 2.9e-05 24.1 0.8 0.008 16.1 0.1 3.6 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 AEO67757.1 - 5.1e-05 22.4 0.0 9.1e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 AEO67757.1 - 0.00053 18.8 0.1 0.00086 18.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 AEO67757.1 - 0.0017 17.7 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 AEO67757.1 - 0.0017 18.0 0.1 0.0067 16.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 AEO67757.1 - 0.0018 17.8 0.1 0.0052 16.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 AEO67757.1 - 0.0033 16.6 0.1 0.0081 15.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 AEO67757.1 - 0.0037 16.9 0.1 0.028 14.1 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_2 PF07724.9 AEO67757.1 - 0.0046 16.8 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 AEO67757.1 - 0.0099 15.7 0.0 0.033 14.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 AEO67757.1 - 0.01 14.7 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 AEO67757.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 AEO67757.1 - 0.018 14.4 0.7 0.22 10.9 0.1 2.6 1 1 2 3 3 3 0 AAA domain AAA_17 PF13207.1 AEO67757.1 - 0.019 15.7 0.0 0.11 13.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 AEO67757.1 - 0.032 13.8 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AEO67757.1 - 0.051 13.5 0.8 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 AEO67757.1 - 0.062 12.9 0.0 0.25 11.0 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 AEO67757.1 - 0.09 12.4 0.0 0.4 10.3 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase Guanylate_kin PF00625.16 AEO67757.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase PhoH PF02562.11 AEO67757.1 - 0.16 11.1 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 AEO67757.1 - 0.18 11.2 0.0 0.47 9.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain COG6 PF06419.6 AEO67758.1 - 5e-224 745.0 6.9 5.7e-224 744.8 4.8 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DASH_Dad3 PF08656.5 AEO67758.1 - 0.0002 21.0 0.2 0.051 13.2 0.0 3.2 2 0 0 2 2 2 1 DASH complex subunit Dad3 DUF1612 PF07756.7 AEO67758.1 - 0.056 13.5 3.3 11 6.1 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) Seryl_tRNA_N PF02403.17 AEO67758.1 - 0.076 13.0 5.9 0.025 14.5 1.1 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.6 AEO67758.1 - 0.076 12.8 4.7 0.1 12.4 0.4 3.0 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 APG9 PF04109.11 AEO67759.1 - 2.6e-156 520.1 2.8 3.3e-156 519.8 1.9 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF3894 PF13033.1 AEO67759.1 - 0.65 10.0 5.1 0.17 11.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3894) Mito_carr PF00153.22 AEO67760.1 - 2.3e-72 238.7 6.3 9.6e-25 86.1 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.26 AEO67761.1 - 8e-24 83.1 1.9 8e-24 83.1 1.3 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 AEO67761.1 - 1e-20 73.1 12.5 4.2e-07 29.5 0.0 5.0 3 1 2 5 5 5 5 TPR repeat TPR_2 PF07719.12 AEO67761.1 - 9.8e-18 62.5 19.8 0.011 15.6 0.2 8.9 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 AEO67761.1 - 8.7e-17 61.3 8.3 0.00095 19.7 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 AEO67761.1 - 2.9e-15 55.1 8.1 0.00051 19.5 0.0 7.7 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 AEO67761.1 - 6.7e-14 51.1 10.5 0.39 11.4 0.0 8.2 4 2 5 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 AEO67761.1 - 3.2e-11 42.1 7.6 0.0094 15.6 0.0 7.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 AEO67761.1 - 3.9e-11 42.6 1.4 4.6e-05 23.1 0.6 3.9 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 AEO67761.1 - 1e-07 31.9 12.4 0.21 12.1 0.0 7.9 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 AEO67761.1 - 2.4e-07 30.3 3.1 0.015 15.4 0.0 5.6 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 AEO67761.1 - 4.6e-07 30.0 12.4 0.0096 16.2 0.0 5.5 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 AEO67761.1 - 0.00013 21.5 8.4 0.22 11.4 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 AEO67761.1 - 0.00023 21.0 18.9 0.00057 19.7 0.0 6.0 3 2 4 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 AEO67761.1 - 0.0049 15.9 6.6 6.1 5.8 0.0 4.7 3 2 1 4 4 4 2 Tetratricopeptide repeat BAR PF03114.13 AEO67761.1 - 0.0096 15.4 2.5 0.27 10.7 0.2 2.5 2 0 0 2 2 2 1 BAR domain Type_III_YscG PF09477.5 AEO67761.1 - 0.027 14.5 0.3 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) BTAD PF03704.12 AEO67761.1 - 0.039 14.2 9.7 0.043 14.1 0.0 4.0 3 1 1 4 4 4 0 Bacterial transcriptional activator domain SLS PF14611.1 AEO67761.1 - 0.11 11.8 0.1 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator UPF0150 PF03681.10 AEO67761.1 - 0.38 10.4 2.6 0.44 10.2 0.7 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0150) HemY_N PF07219.8 AEO67761.1 - 3.8 7.0 7.2 4.5 6.8 2.9 2.7 2 0 0 2 2 2 0 HemY protein N-terminus Gar1 PF04410.9 AEO67762.1 - 4.9e-43 146.2 0.3 4.9e-43 146.2 0.2 1.8 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region Prominin PF05478.6 AEO67763.1 - 0.0023 15.5 0.4 0.0031 15.1 0.2 1.2 1 0 0 1 1 1 1 Prominin EMG1 PF03587.9 AEO67765.1 - 4.4e-77 257.9 0.0 5e-77 257.7 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Gly-zipper_OmpA PF13436.1 AEO67766.1 - 0.14 11.8 2.0 0.32 10.6 1.4 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Cys_Met_Meta_PP PF01053.15 AEO67767.1 - 2.3e-34 118.3 0.0 3.2e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 AEO67767.1 - 0.00055 18.9 0.0 0.0034 16.3 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II SPX PF03105.14 AEO67768.1 - 2.9e-36 125.6 0.0 3.8e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.20 AEO67768.1 - 1.4e-06 27.8 13.6 2.3e-06 27.1 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO67768.1 - 2.3e-05 24.1 13.5 4e-05 23.3 9.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AEO67768.1 - 2.7e-05 23.7 10.6 4.1e-05 23.1 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AEO67768.1 - 0.00017 21.4 13.4 0.00029 20.6 9.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 AEO67768.1 - 0.00045 19.8 11.7 0.00077 19.1 8.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO67768.1 - 0.0018 18.2 14.9 0.0033 17.4 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) NIR_SIR PF01077.17 AEO67768.1 - 0.076 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain zf-RING_6 PF14835.1 AEO67768.1 - 0.24 11.2 5.0 0.57 9.9 3.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 AEO67768.1 - 0.3 10.8 9.1 0.78 9.5 6.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.2 AEO67768.1 - 2.7 7.8 6.7 5.1 6.9 4.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon DnaJ PF00226.26 AEO67769.1 - 2e-25 88.2 0.6 2e-25 88.2 0.4 2.5 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 AEO67769.1 - 7.2e-11 41.9 2.1 7.2e-11 41.9 1.5 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO67769.1 - 1e-10 41.4 7.8 1.7e-09 37.5 1.5 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 AEO67769.1 - 3.6e-08 33.4 5.3 5.6e-05 23.1 1.5 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 AEO67769.1 - 1e-05 25.5 5.0 0.064 13.6 0.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 AEO67769.1 - 1.1e-05 25.1 6.1 0.0066 16.3 0.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 AEO67769.1 - 0.00084 19.5 4.8 0.13 12.6 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger RPT PF13446.1 AEO67769.1 - 0.0094 15.3 0.1 0.057 12.8 0.0 2.3 2 0 0 2 2 2 1 A repeated domain in UCH-protein zf-H2C2_2 PF13465.1 AEO67769.1 - 0.12 12.7 0.6 4.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double domain CpXC PF14353.1 AEO67769.1 - 0.15 12.0 7.4 0.23 11.4 1.1 3.1 2 1 1 3 3 3 0 CpXC protein Tmemb_55A PF09788.4 AEO67769.1 - 0.86 8.6 3.5 2.2 7.3 0.6 2.2 2 0 0 2 2 2 0 Transmembrane protein 55A DUF2387 PF09526.5 AEO67769.1 - 1.3 8.9 7.9 0.38 10.6 2.5 2.4 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Peptidase_C54 PF03416.14 AEO67770.1 - 6.7e-97 323.9 0.0 8.1e-97 323.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_M14 PF00246.19 AEO67770.1 - 0.096 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Zinc carboxypeptidase G-patch PF01585.18 AEO67771.1 - 1.4e-11 43.9 2.3 3.5e-11 42.7 1.6 1.7 1 0 0 1 1 1 1 G-patch domain R3H PF01424.17 AEO67771.1 - 8e-11 41.4 0.2 2.4e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 R3H domain TIP_N PF12457.3 AEO67771.1 - 0.001 19.1 0.6 0.001 19.1 0.4 3.4 4 0 0 4 4 4 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.2 AEO67771.1 - 0.0061 16.3 2.8 0.0087 15.8 0.7 2.3 2 0 0 2 2 2 1 DExH-box splicing factor binding site Histone PF00125.19 AEO67772.1 - 9.5e-22 76.9 0.2 1.3e-21 76.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AEO67772.1 - 4.2e-05 23.5 0.0 9.9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 AEO67772.1 - 0.00021 21.4 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 AEO67772.1 - 0.0076 14.9 1.5 0.0094 14.6 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein RP-C PF03428.8 AEO67772.1 - 0.023 14.1 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 AEO67772.1 - 0.028 14.9 0.4 0.038 14.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Glyco_hydro_53 PF07745.8 AEO67772.1 - 0.064 12.0 0.0 0.075 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Histone PF00125.19 AEO67773.1 - 8.4e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AEO67773.1 - 1.3e-05 25.2 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.10 AEO67774.1 - 7.3e-11 41.6 2.3 1e-10 41.2 1.6 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AEO67774.1 - 2.2e-08 34.1 1.2 3.3e-08 33.6 0.8 1.3 1 0 0 1 1 1 1 Complex1_LYR-like 2-oxoacid_dh PF00198.18 AEO67775.1 - 4.3e-81 271.5 0.1 5.9e-81 271.1 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 AEO67775.1 - 8.6e-19 66.9 2.0 1.5e-18 66.1 1.4 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 AEO67775.1 - 0.00023 20.4 0.4 0.0037 16.4 0.1 2.5 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 AEO67775.1 - 0.0014 18.2 0.9 0.045 13.4 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 AEO67775.1 - 0.024 14.9 0.3 7.1 7.0 0.0 2.4 1 1 1 2 2 2 0 HlyD family secretion protein DUF3614 PF12267.3 AEO67775.1 - 0.2 11.9 4.1 1.5 9.0 0.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3614) Trypan_PARP PF05887.6 AEO67775.1 - 0.38 10.5 17.9 0.65 9.8 12.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ndc1_Nup PF09531.5 AEO67775.1 - 0.44 8.8 5.0 0.58 8.5 3.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2397 PF09660.5 AEO67775.1 - 1.1 7.8 3.7 1.6 7.2 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) AA_permease PF00324.16 AEO67776.1 - 9e-24 83.6 12.5 3.5e-23 81.7 8.7 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO67776.1 - 1.2e-09 37.2 6.6 1.6e-09 36.8 4.6 1.2 1 0 0 1 1 1 1 Amino acid permease DUF4212 PF13937.1 AEO67776.1 - 0.1 12.6 1.4 0.28 11.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) VirB3 PF05101.8 AEO67776.1 - 0.47 10.4 4.6 0.38 10.7 0.1 2.7 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein AA_permease PF00324.16 AEO67777.1 - 0.0012 17.2 0.1 0.0013 17.1 0.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO67778.1 - 3.7e-21 75.0 7.6 4.5e-21 74.7 5.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO67778.1 - 3.3e-06 25.9 7.1 4e-06 25.6 5.0 1.1 1 0 0 1 1 1 1 Amino acid permease Fig1 PF12351.3 AEO67778.1 - 0.0017 18.2 3.0 0.002 18.0 2.1 1.0 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF2795 PF11387.3 AEO67779.1 - 0.39 10.6 2.1 8 6.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2795) Pyr_redox_3 PF13738.1 AEO67780.1 - 2.1e-21 76.9 0.0 3.7e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AEO67780.1 - 1.5e-12 46.4 0.1 1.5e-08 33.3 0.1 3.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 AEO67780.1 - 6.3e-10 38.9 0.0 1.6e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 AEO67780.1 - 2e-05 24.4 0.0 0.0028 17.4 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 AEO67780.1 - 0.019 13.8 0.0 3.7 6.3 0.0 3.0 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 AEO67780.1 - 0.058 13.2 0.0 0.24 11.2 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO67780.1 - 0.14 11.2 0.0 0.45 9.5 0.0 1.7 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 AEO67780.1 - 0.21 10.0 0.0 0.32 9.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein RVT_1 PF00078.22 AEO67781.1 - 9.7e-05 21.8 0.5 0.00014 21.2 0.3 1.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PALP PF00291.20 AEO67782.1 - 6.5e-74 248.9 0.6 8.3e-74 248.5 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 AEO67782.1 - 3.1e-39 132.4 0.0 6.9e-20 70.4 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.8 AEO67783.1 - 3.6e-24 84.2 1.0 7.2e-24 83.2 0.7 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2611 PF11022.3 AEO67783.1 - 0.014 15.4 2.5 0.58 10.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2611) DUF1310 PF07006.6 AEO67783.1 - 0.067 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) PRTP PF01366.13 AEO67783.1 - 0.076 10.9 1.4 0.095 10.6 1.0 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein SpaB_C PF14028.1 AEO67783.1 - 0.24 10.9 7.9 0.3 10.6 5.5 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain SHR3_chaperone PF08229.6 AEO67783.1 - 2.2 7.2 5.1 0.61 9.0 1.4 1.6 1 1 1 2 2 2 0 ER membrane protein SH3 UPF0561 PF10573.4 AEO67783.1 - 3.1 7.6 7.4 1.6 8.5 3.7 1.6 1 1 0 1 1 1 0 Uncharacterised protein family UPF0561 OmpH PF03938.9 AEO67783.1 - 3.9 7.3 12.1 5.7 6.8 8.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.1 AEO67783.1 - 5.7 5.8 9.5 8.2 5.2 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Selenoprotein_S PF06936.6 AEO67783.1 - 6.2 6.3 13.3 2.5 7.6 7.1 1.7 1 1 1 2 2 2 0 Selenoprotein S (SelS) TLD PF07534.11 AEO67784.1 - 8.2e-29 100.3 0.0 3e-28 98.5 0.0 1.8 1 1 0 1 1 1 1 TLD MUG2_C PF08593.5 AEO67784.1 - 9.3e-17 61.0 0.2 2.9e-16 59.4 0.1 1.9 2 0 0 2 2 2 1 Meiotically up-regulated glycoproteins C-terminal RPEL PF02755.10 AEO67786.1 - 2.8e-19 67.7 5.2 4e-11 41.8 0.1 2.7 3 0 0 3 3 3 2 RPEL repeat FKBP_C PF00254.23 AEO67788.1 - 3.9e-32 110.1 0.0 5.6e-32 109.6 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cytomega_UL20A PF05984.7 AEO67788.1 - 0.049 13.8 0.0 0.092 12.9 0.0 1.4 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein TrkH PF02386.11 AEO67789.1 - 3.3e-93 312.0 4.5 3.4e-89 298.8 0.2 2.1 2 0 0 2 2 2 2 Cation transport protein IMS PF00817.15 AEO67790.1 - 2.3e-43 147.5 0.1 5.3e-43 146.3 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 AEO67790.1 - 2.1e-16 60.0 0.1 5.7e-16 58.6 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 AEO67790.1 - 2.3e-05 24.1 0.0 6.1e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif FYVE PF01363.16 AEO67791.1 - 0.0037 17.1 4.5 0.01 15.7 3.2 1.7 1 1 0 1 1 1 1 FYVE zinc finger DZR PF12773.2 AEO67791.1 - 0.13 12.0 4.3 2 8.3 3.0 2.2 1 1 0 1 1 1 0 Double zinc ribbon IBR PF01485.16 AEO67791.1 - 0.7 9.8 5.7 1.9 8.4 4.0 1.8 1 1 0 1 1 1 0 IBR domain zf-RanBP PF00641.13 AEO67791.1 - 1.4 8.1 8.2 0.12 11.5 0.5 2.6 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others FYVE_2 PF02318.11 AEO67791.1 - 1.7 8.5 4.0 0.52 10.2 0.7 1.6 2 0 0 2 2 2 0 FYVE-type zinc finger Memo PF01875.12 AEO67792.1 - 6e-74 248.3 0.0 7.1e-74 248.1 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein SNARE PF05739.14 AEO67793.1 - 1.5e-10 40.5 14.7 7.9e-10 38.2 5.9 3.4 3 0 0 3 3 3 1 SNARE domain Rifin_STEVOR PF02009.11 AEO67793.1 - 2.9e-05 23.8 1.5 5e-05 23.0 1.1 1.4 1 0 0 1 1 1 1 Rifin/stevor family Syntaxin PF00804.20 AEO67793.1 - 0.002 18.2 10.2 0.028 14.5 7.1 2.6 1 1 0 1 1 1 1 Syntaxin DUF912 PF06024.7 AEO67793.1 - 0.0021 18.0 0.7 0.0052 16.8 0.5 1.7 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1510 PF07423.6 AEO67793.1 - 0.0045 16.3 0.1 0.0082 15.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) PDR_CDR PF06422.7 AEO67793.1 - 0.013 15.1 0.2 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 CDR ABC transporter Foamy_virus_ENV PF03408.9 AEO67793.1 - 0.019 12.4 1.5 0.027 12.0 1.0 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein DUF1634 PF07843.6 AEO67793.1 - 0.025 14.1 0.2 0.05 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) MLANA PF14991.1 AEO67793.1 - 0.036 14.0 1.1 0.2 11.6 0.1 2.2 2 0 0 2 2 2 0 Protein melan-A MSC PF09402.5 AEO67793.1 - 0.054 12.2 2.0 0.091 11.4 1.4 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF2370 PF10176.4 AEO67793.1 - 0.06 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) YlqD PF11068.3 AEO67793.1 - 0.069 13.1 17.9 2 8.4 0.8 2.9 1 1 1 2 2 2 0 YlqD protein Wzy_C PF04932.10 AEO67793.1 - 0.097 12.4 0.1 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 O-Antigen ligase YniB PF14002.1 AEO67793.1 - 0.19 11.1 2.0 0.58 9.5 0.2 2.5 2 1 0 2 2 2 0 YniB-like protein Serine_rich PF08824.5 AEO67793.1 - 0.4 10.3 8.1 0.2 11.3 0.2 2.4 1 1 0 2 2 2 0 Serine rich protein interaction domain Kinetocho_Slk19 PF12709.2 AEO67793.1 - 0.75 9.9 4.3 0.2 11.7 0.1 2.1 2 1 1 3 3 2 0 Central kinetochore-associated DUF4446 PF14584.1 AEO67793.1 - 2.1 8.1 11.0 2.4 7.9 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4446) zf-Apc11 PF12861.2 AEO67795.1 - 2e-45 152.5 11.6 2.3e-45 152.3 8.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 AEO67795.1 - 3.4e-33 113.5 11.1 3.9e-33 113.3 7.7 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 AEO67795.1 - 8.7e-09 35.0 16.5 5.5e-08 32.5 11.4 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AEO67795.1 - 6.1e-05 22.5 13.8 0.00024 20.6 9.5 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO67795.1 - 7.6e-05 22.2 12.1 0.0018 17.9 8.4 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO67795.1 - 0.00023 21.1 14.2 0.0016 18.4 9.8 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AEO67795.1 - 0.00036 20.3 4.4 0.00036 20.3 3.0 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 AEO67795.1 - 0.0013 18.3 3.1 0.0013 18.3 2.1 2.3 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 AEO67795.1 - 0.014 15.3 17.0 0.3 11.0 11.8 3.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.1 AEO67795.1 - 0.015 14.9 16.2 0.34 10.6 11.6 2.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.3 AEO67795.1 - 0.031 13.7 5.9 0.058 12.9 4.1 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HIT PF04438.11 AEO67795.1 - 0.034 13.7 4.9 0.055 13.1 0.7 2.4 2 0 0 2 2 2 0 HIT zinc finger Opy2 PF09463.5 AEO67795.1 - 0.26 11.3 10.8 1.9 8.6 4.5 2.3 2 0 0 2 2 2 0 Opy2 protein DUF2256 PF10013.4 AEO67795.1 - 0.27 11.0 0.3 0.27 11.0 0.2 3.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING-like PF08746.6 AEO67795.1 - 1.8 8.6 14.1 9.5 6.3 9.8 2.1 1 1 0 1 1 1 0 RING-like domain RINGv PF12906.2 AEO67795.1 - 2.8 8.0 12.8 8 6.6 8.6 2.1 1 1 0 1 1 1 0 RING-variant domain zf-HC5HC2H_2 PF13832.1 AEO67795.1 - 3.6 7.6 10.3 3 7.8 4.4 2.2 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 AEO67795.1 - 3.7 7.7 11.1 2 8.6 4.3 2.3 1 1 1 2 2 2 0 PHD-like zinc-binding domain DUF329 PF03884.9 AEO67795.1 - 3.8 7.1 8.2 1.6 8.3 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF329) DZR PF12773.2 AEO67795.1 - 4.1 7.3 12.5 11 5.9 4.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon Elf1 PF05129.8 AEO67795.1 - 4.9 6.9 7.0 0.55 9.9 0.2 2.3 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zinc-ribbons_6 PF07191.7 AEO67795.1 - 7 6.5 10.2 5.4 6.8 0.1 2.6 1 1 2 3 3 3 0 zinc-ribbons zf-RING_UBOX PF13445.1 AEO67795.1 - 9.8 5.9 10.6 1.4 8.7 4.2 2.1 2 1 1 3 3 2 0 RING-type zinc-finger Rhodanese PF00581.15 AEO67796.1 - 4.3e-21 75.3 0.0 6.4e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain GMC_oxred_N PF00732.14 AEO67797.1 - 8.5e-57 192.5 0.0 1.1e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO67797.1 - 3.8e-30 105.0 0.0 6.8e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 AEO67797.1 - 9.2e-05 21.5 0.6 0.0012 17.8 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO67797.1 - 0.00079 19.3 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 AEO67797.1 - 0.0032 16.3 0.0 0.16 10.7 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 AEO67797.1 - 0.013 14.4 0.1 0.021 13.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Glyco_hydro_18 PF00704.23 AEO67798.1 - 1.1e-46 159.9 0.0 1.3e-46 159.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 WD40 PF00400.27 AEO67799.1 - 2.1e-05 24.2 3.7 0.044 13.6 0.4 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Nucleoplasmin PF03066.10 AEO67799.1 - 0.0074 15.8 3.7 0.013 15.0 2.5 1.4 1 0 0 1 1 1 1 Nucleoplasmin CDC45 PF02724.9 AEO67799.1 - 0.043 11.8 4.2 0.057 11.4 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein PQQ_3 PF13570.1 AEO67799.1 - 0.055 13.7 1.5 16 5.9 0.3 3.9 3 1 0 3 3 3 0 PQQ-like domain PBP1_TM PF14812.1 AEO67799.1 - 0.23 11.7 10.5 0.52 10.6 7.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIF_alpha PF05793.7 AEO67799.1 - 0.37 9.0 10.5 0.59 8.4 7.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nucleo_P87 PF07267.6 AEO67799.1 - 4.4 5.8 4.5 5.8 5.4 3.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Inositol_P PF00459.20 AEO67800.1 - 7.4e-80 268.1 0.0 8.7e-80 267.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DHquinase_II PF01220.14 AEO67801.1 - 7.6e-58 193.7 0.1 1.2e-57 193.1 0.0 1.3 1 1 0 1 1 1 1 Dehydroquinase class II AP_endonuc_2 PF01261.19 AEO67802.1 - 2.1e-33 115.3 0.0 3e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Shikimate_dh_N PF08501.6 AEO67803.1 - 6.8e-20 70.9 0.0 1.1e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 AEO67803.1 - 2.6e-16 59.9 0.0 4.2e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 AEO67803.1 - 0.0076 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Saccharop_dh PF03435.13 AEO67803.1 - 0.06 12.3 0.0 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Sugar_tr PF00083.19 AEO67804.1 - 8.7e-135 449.7 22.5 9.9e-135 449.5 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO67804.1 - 2.3e-27 95.6 65.0 2e-26 92.5 24.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DHquinase_I PF01487.10 AEO67805.1 - 1.2e-41 142.8 0.0 2.3e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 AEO67805.1 - 7.1e-22 77.2 0.2 1.5e-21 76.2 0.1 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 AEO67805.1 - 7.3e-15 55.1 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 AEO67805.1 - 1.3e-11 44.7 0.1 2.8e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 AEO67805.1 - 0.0061 17.3 0.0 0.014 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AEO67805.1 - 0.016 14.3 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.24 AEO67805.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Fungal_trans PF04082.13 AEO67806.1 - 1.7e-10 40.2 0.0 2.6e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO67806.1 - 2.4e-06 27.3 10.3 4.6e-06 26.4 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_2 PF00890.19 AEO67807.1 - 9.8e-57 192.6 8.1 1.4e-56 192.1 5.6 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO67807.1 - 1.3e-09 37.4 1.0 3.7e-09 35.9 0.7 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO67807.1 - 6.1e-08 32.5 0.6 2.8e-07 30.4 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AEO67807.1 - 4.3e-06 26.9 0.2 7.4e-06 26.1 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO67807.1 - 5.1e-06 25.8 1.5 8.3e-06 25.1 1.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 AEO67807.1 - 1.2e-05 24.3 3.9 0.00046 19.1 0.2 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.9 AEO67807.1 - 8.8e-05 21.1 5.2 0.0026 16.2 0.3 3.3 4 0 0 4 4 4 1 HI0933-like protein Pyr_redox_2 PF07992.9 AEO67807.1 - 0.001 18.9 0.7 0.0077 16.1 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO67807.1 - 0.0028 16.8 0.8 0.011 14.8 0.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 AEO67807.1 - 0.0043 16.1 1.3 0.0046 16.0 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 AEO67807.1 - 0.039 12.8 0.4 0.066 12.1 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 AEO67807.1 - 0.047 14.0 0.7 0.35 11.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Grp1_Fun34_YaaH PF01184.14 AEO67808.1 - 2.5e-87 291.5 15.5 3e-87 291.3 10.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Ribosomal_S5 PF00333.15 AEO67809.1 - 2.2e-28 97.8 2.1 2.2e-28 97.8 1.4 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 AEO67809.1 - 3.1e-20 71.2 0.0 3.1e-20 71.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S30 PF04758.9 AEO67810.1 - 5.1e-26 90.1 4.1 6e-26 89.9 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 MARVEL PF01284.18 AEO67811.1 - 5.6e-11 42.4 19.2 6.5e-11 42.2 13.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain UPF0233 PF06781.7 AEO67811.1 - 3.4 7.3 6.0 4.6 6.9 3.4 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0233) Abhydrolase_4 PF08386.5 AEO67812.1 - 4.9e-16 58.4 0.4 1.1e-15 57.3 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 AEO67812.1 - 7.6e-10 38.7 0.1 4.8e-07 29.5 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AEO67812.1 - 4.6e-07 29.9 11.6 1e-06 28.8 4.9 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO67812.1 - 0.00014 21.6 0.1 0.002 17.9 0.0 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family FHA PF00498.21 AEO67813.1 - 4.4e-10 39.5 0.1 7.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 AEO67813.1 - 0.00084 19.4 0.1 0.015 15.4 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AEO67813.1 - 0.03 14.1 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain Nbs1_C PF08599.5 AEO67813.1 - 0.04 13.8 2.4 0.042 13.7 0.0 2.3 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 Cyt-b5 PF00173.23 AEO67814.1 - 6.7e-15 54.6 0.0 1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Microtub_bind PF13931.1 AEO67815.1 - 0.21 11.7 5.6 0.55 10.3 0.2 2.4 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding Tnp_P_element PF12017.3 AEO67815.1 - 2.2 7.4 3.1 5.9 6.0 0.1 2.1 2 0 0 2 2 2 0 Transposase protein DnaJ-X PF14308.1 AEO67816.1 - 1.9e-68 229.7 3.5 1.9e-68 229.7 2.4 1.8 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 AEO67816.1 - 6.1e-27 93.1 0.9 1.3e-26 92.0 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain PspB PF06667.7 AEO67816.1 - 0.29 11.1 1.4 0.69 9.8 1.0 1.6 1 0 0 1 1 1 0 Phage shock protein B RmlD_sub_bind PF04321.12 AEO67817.1 - 3.6e-14 52.3 0.0 9.2e-14 50.9 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 AEO67817.1 - 9.5e-14 51.4 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 AEO67817.1 - 9.4e-05 21.4 0.0 0.00021 20.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 AEO67817.1 - 0.0038 17.1 0.0 0.0089 15.9 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase SQS_PSY PF00494.14 AEO67818.1 - 5.8e-40 137.2 0.0 1.7e-39 135.7 0.0 1.7 2 0 0 2 2 2 1 Squalene/phytoene synthase Peptidase_S8 PF00082.17 AEO67819.1 - 2.4e-44 151.6 18.5 3.2e-44 151.1 12.8 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 AEO67819.1 - 0.045 14.3 0.1 0.11 13.1 0.1 1.7 1 0 0 1 1 1 0 Peptidase inhibitor I9 F-box-like PF12937.2 AEO67821.1 - 0.00044 19.9 1.2 0.0023 17.6 0.1 2.5 2 0 0 2 2 2 1 F-box-like Mannosyl_trans PF05007.8 AEO67822.1 - 3e-49 168.0 0.8 3.4e-48 164.5 0.6 2.1 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 AEO67822.1 - 3.1e-13 49.3 1.1 5.3e-13 48.5 0.7 1.4 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 AEO67822.1 - 3.7e-05 23.3 11.2 3.7e-05 23.3 7.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2029) Translin PF01997.11 AEO67823.1 - 4.7e-63 212.4 0.0 5.6e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Translin family EF1_GNE PF00736.14 AEO67824.1 - 2.5e-33 113.6 2.4 4.3e-33 112.8 1.7 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 AEO67824.1 - 1.7e-14 53.6 9.0 1.7e-14 53.6 6.2 2.6 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 AEO67824.1 - 0.0016 18.8 0.3 0.0041 17.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AEO67824.1 - 0.0068 16.3 0.1 0.0068 16.3 0.1 2.2 2 2 0 2 2 2 1 Glutathione S-transferase, C-terminal domain MRP-S26 PF14943.1 AEO67824.1 - 0.15 11.5 4.4 0.048 13.2 1.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 DNA_pol3_a_NII PF11490.3 AEO67824.1 - 7.3 6.2 10.2 0.81 9.3 0.1 2.3 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II WD40 PF00400.27 AEO67825.1 - 1.4e-21 75.5 10.6 1.5e-08 34.1 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat CTP_transf_2 PF01467.21 AEO67826.1 - 0.00025 21.1 0.9 0.0038 17.2 0.6 2.6 1 1 0 1 1 1 1 Cytidylyltransferase ADH_zinc_N PF00107.21 AEO67827.1 - 2.9e-12 46.2 0.0 3.8e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO67827.1 - 0.0035 18.2 0.0 0.0052 17.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NmrA PF05368.8 AEO67828.1 - 9.2e-05 21.8 0.0 0.0001 21.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Ribosomal_L36 PF00444.13 AEO67829.1 - 4.9e-22 77.6 10.1 7.6e-22 77.0 7.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Med3 PF11593.3 AEO67829.1 - 0.18 11.0 9.2 0.19 10.9 6.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Complex1_LYR_1 PF13232.1 AEO67830.1 - 3.4e-17 62.4 0.7 3.4e-17 62.4 0.5 2.0 1 1 1 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 AEO67830.1 - 1.9e-16 59.6 1.2 1.9e-16 59.6 0.9 1.9 2 1 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 AEO67830.1 - 0.066 13.6 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Complex1_LYR-like Put_Phosphatase PF06888.7 AEO67832.1 - 0.0096 15.1 0.2 0.018 14.2 0.1 1.5 1 0 0 1 1 1 1 Putative Phosphatase Acetyltransf_1 PF00583.19 AEO67834.1 - 1.5e-11 44.1 0.0 2.5e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO67834.1 - 4e-05 23.6 0.0 7.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO67834.1 - 4.2e-05 23.6 0.0 6.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO67834.1 - 0.0006 19.5 0.0 0.0022 17.7 0.0 1.9 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.1 AEO67834.1 - 0.0044 17.1 0.0 0.031 14.4 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain p450 PF00067.17 AEO67835.1 - 5.5e-17 61.4 0.0 1.7e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 PIG-S PF10510.4 AEO67836.1 - 1.2e-152 509.2 0.1 1.4e-152 509.0 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein AMP-binding PF00501.23 AEO67837.1 - 4.8e-63 212.9 0.0 5.9e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO67837.1 - 3.5e-11 43.8 0.4 7.7e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AhpC-TSA PF00578.16 AEO67838.1 - 2.8e-32 111.0 0.0 3.7e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 AEO67838.1 - 8.7e-13 47.6 0.2 1.8e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 AEO67838.1 - 2.9e-11 43.0 0.0 3.9e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin Kelch_3 PF13415.1 AEO67839.1 - 2e-20 72.3 2.5 1.2e-10 41.2 0.0 5.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 AEO67839.1 - 4.1e-20 71.2 1.1 8.6e-10 38.2 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 AEO67839.1 - 3.3e-14 52.4 3.7 3.1e-06 26.9 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 AEO67839.1 - 4.8e-12 45.2 0.1 0.00025 20.5 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 AEO67839.1 - 4e-11 42.5 1.5 0.00071 19.6 0.1 4.9 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.10 AEO67839.1 - 1e-08 34.5 0.5 0.0014 18.3 0.0 4.7 5 1 0 5 5 5 2 Kelch motif BTB PF00651.26 AEO67839.1 - 0.0024 17.8 0.0 0.043 13.8 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain MFS_1 PF07690.11 AEO67840.1 - 1.1e-24 86.8 31.2 3.4e-24 85.2 21.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO67840.1 - 0.0075 14.8 16.8 0.068 11.7 3.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Sulfatase PF00884.18 AEO67841.1 - 1.7e-65 221.2 0.2 2.3e-65 220.8 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 AEO67841.1 - 0.00091 18.6 0.6 0.0066 15.8 0.5 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 AEO67841.1 - 0.086 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) MFS_1 PF07690.11 AEO67842.1 - 9.5e-28 96.9 25.3 1.2e-27 96.5 17.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 AEO67842.1 - 2.8 8.0 10.3 0.19 11.7 0.6 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) adh_short PF00106.20 AEO67843.1 - 4.6e-22 78.7 1.6 6.7e-22 78.1 1.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO67843.1 - 1.1e-21 77.7 0.0 1.4e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DLH PF01738.13 AEO67843.1 - 1.6e-20 73.3 0.0 2.4e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AEO67843.1 - 2.9e-05 23.8 0.1 0.00034 20.4 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family KR PF08659.5 AEO67843.1 - 0.00035 20.2 0.4 0.00058 19.5 0.3 1.3 1 0 0 1 1 1 1 KR domain Peptidase_S9 PF00326.16 AEO67843.1 - 0.046 12.9 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family 3HCDH_N PF02737.13 AEO67843.1 - 0.16 11.6 0.3 0.51 9.9 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.13 AEO67844.1 - 1.6e-22 79.6 0.6 7.1e-21 74.2 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Pyr_redox PF00070.22 AEO67845.1 - 3.2e-10 40.2 0.3 6.3e-07 29.7 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 AEO67845.1 - 0.0068 15.4 0.1 0.36 9.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 AEO67845.1 - 0.022 14.6 0.0 0.3 10.9 0.0 2.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO67845.1 - 0.031 14.3 0.0 2.5 8.1 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 AEO67846.1 - 5.7e-29 101.1 0.1 8.7e-29 100.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO67846.1 - 2.3e-11 43.6 0.0 3.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO67846.1 - 7.2e-06 25.5 0.0 9.9e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 AEO67846.1 - 7.1e-05 22.6 0.0 9.6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PALP PF00291.20 AEO67846.1 - 0.033 13.4 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF3336 PF11815.3 AEO67847.1 - 4.4e-39 133.2 2.0 1e-38 132.1 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 AEO67847.1 - 1.7e-22 80.3 0.1 4.8e-22 78.8 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase Abhydrolase_5 PF12695.2 AEO67848.1 - 3.5e-07 30.0 0.0 4.3e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO67848.1 - 0.0054 15.9 0.0 0.023 13.9 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF3445 PF11927.3 AEO67850.1 - 5.3e-55 186.5 0.0 7.8e-55 185.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF377 PF04041.8 AEO67857.1 - 0.11 11.2 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF377) RVT_1 PF00078.22 AEO67859.1 - 2.6e-06 26.9 0.4 3e-06 26.7 0.3 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF713 PF05218.9 AEO67861.1 - 0.096 12.4 1.4 0.12 12.1 0.9 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF713) Sugar_tr PF00083.19 AEO67862.1 - 7.6e-86 288.4 27.1 9.6e-86 288.1 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO67862.1 - 3.1e-14 52.4 46.6 6.2e-09 35.0 8.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclin PF08613.6 AEO67863.1 - 1e-38 133.0 0.6 9.2e-23 81.3 0.1 2.4 2 0 0 2 2 2 2 Cyclin Proteasome PF00227.21 AEO67864.1 - 2.9e-48 163.7 0.1 3.3e-48 163.5 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Evr1_Alr PF04777.8 AEO67865.1 - 2.5e-27 94.6 0.0 3.5e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family Toxin-deaminase PF14424.1 AEO67865.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases TT_ORF2a PF08197.6 AEO67866.1 - 1.8 8.3 9.3 0.76 9.5 1.1 2.9 1 1 1 2 2 2 0 pORF2a truncated protein Pkinase PF00069.20 AEO67867.1 - 4.2e-13 49.0 0.0 6.4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 AEO67867.1 - 0.0026 16.7 0.0 0.004 16.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 AEO67867.1 - 0.0053 15.8 0.0 0.0081 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Inhibitor_I10 PF12559.3 AEO67867.1 - 0.6 10.4 2.6 5.9 7.2 0.1 3.0 3 0 0 3 3 3 0 Serine endopeptidase inhibitors C2 PF00168.25 AEO67869.1 - 2.8e-06 27.0 0.0 5.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF2360 PF10152.4 AEO67869.1 - 2.5 8.3 5.4 1.9 8.7 1.6 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) TRAPPC10 PF12584.3 AEO67870.1 - 2.3e-20 72.6 0.0 4.3e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Serglycin PF04360.7 AEO67870.1 - 0.034 13.8 1.6 0.3 10.7 0.3 2.5 2 0 0 2 2 2 0 Serglycin Foie-gras_1 PF11817.3 AEO67870.1 - 0.041 13.3 0.1 0.073 12.5 0.1 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 Apc3 PF12895.2 AEO67870.1 - 0.12 12.5 0.2 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 IF-2B PF01008.12 AEO67871.1 - 1.7e-71 240.5 0.2 2e-71 240.2 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Prenyltrans PF00432.16 AEO67872.1 - 1.4e-33 114.0 17.5 4.9e-11 41.9 0.1 6.7 7 1 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 AEO67872.1 - 2.4e-19 69.7 0.0 1e-12 48.4 0.0 3.5 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 AEO67872.1 - 1.8e-09 37.5 0.1 0.00091 19.2 0.0 3.9 3 1 0 3 3 3 2 Prenyltransferase-like A2M_comp PF07678.9 AEO67872.1 - 0.052 12.7 0.0 16 4.6 0.0 3.0 3 0 0 3 3 3 0 A-macroglobulin complement component Ilm1 PF10311.4 AEO67873.1 - 9.7e-54 181.3 0.1 1.6e-53 180.5 0.1 1.3 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 NatB_MDM20 PF09797.4 AEO67874.1 - 3.4e-91 305.6 0.0 6.9e-91 304.6 0.0 1.5 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 AEO67874.1 - 1.5 9.2 8.2 0.52 10.6 0.2 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1903 PF08991.5 AEO67875.1 - 5.1e-06 26.5 1.8 6.8e-06 26.1 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 AEO67875.1 - 0.00013 21.7 1.7 0.00041 20.1 1.1 1.8 1 1 1 2 2 2 1 CHCH domain COX6B PF02297.12 AEO67875.1 - 0.00073 19.5 5.3 0.0014 18.6 3.6 1.6 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb UPF0203 PF05254.7 AEO67875.1 - 0.012 15.4 3.8 0.049 13.4 2.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 AEO67875.1 - 0.13 12.3 2.2 0.26 11.3 1.5 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 SlyX PF04102.7 AEO67876.1 - 0.0048 17.2 6.1 0.028 14.7 0.0 3.7 3 1 1 4 4 4 1 SlyX DUF3584 PF12128.3 AEO67876.1 - 0.011 13.0 2.6 0.015 12.7 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Macoilin PF09726.4 AEO67876.1 - 0.056 11.7 8.4 0.068 11.4 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein KdpC PF02669.10 AEO67876.1 - 0.096 12.3 0.9 0.19 11.4 0.6 1.6 1 0 0 1 1 1 0 K+-transporting ATPase, c chain DUF1515 PF07439.6 AEO67876.1 - 0.11 12.2 2.3 1.8 8.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Glyco_hydro_76 PF03663.9 AEO67877.1 - 2.5e-135 451.6 9.3 3.1e-135 451.3 6.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Lipase3_N PF03893.11 AEO67877.1 - 0.1 12.3 0.4 0.75 9.6 0.0 2.4 2 0 0 2 2 2 0 Lipase 3 N-terminal region FUSC PF04632.7 AEO67878.1 - 0.0019 16.7 2.5 0.0027 16.2 1.7 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein family GRP PF07172.6 AEO67878.1 - 0.018 15.4 4.3 0.018 15.4 3.0 2.0 2 0 0 2 2 2 0 Glycine rich protein family APC_CDC26 PF10471.4 AEO67878.1 - 0.019 15.6 0.2 0.019 15.6 0.2 4.7 4 1 1 5 5 5 0 Anaphase-promoting complex APC subunit 1 TSA PF03249.8 AEO67878.1 - 0.62 8.5 5.6 1.1 7.7 3.9 1.3 1 0 0 1 1 1 0 Type specific antigen Fungal_trans PF04082.13 AEO67879.1 - 6.3e-13 48.1 0.0 8.6e-13 47.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF604 PF04646.7 AEO67880.1 - 3.2e-09 36.4 0.0 9.3e-09 34.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF604 Fringe PF02434.11 AEO67880.1 - 7.4e-06 25.3 0.0 1.4e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Fringe-like RabGAP-TBC PF00566.13 AEO67881.1 - 7.9e-31 107.2 0.0 1.6e-30 106.1 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain FTO_NTD PF12933.2 AEO67881.1 - 0.034 13.2 0.3 0.057 12.5 0.2 1.2 1 0 0 1 1 1 0 FTO catalytic domain CVNH PF08881.5 AEO67882.1 - 2.1e-15 56.8 0.0 2.6e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 CVNH domain FA_desaturase PF00487.19 AEO67883.1 - 7.4e-27 94.4 21.3 1.1e-26 93.8 14.8 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 AEO67883.1 - 1.2e-08 35.0 0.0 2.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Syntaxin PF00804.20 AEO67884.1 - 0.0037 17.4 1.7 0.0089 16.1 1.1 1.6 1 0 0 1 1 1 1 Syntaxin ING PF12998.2 AEO67884.1 - 0.02 15.1 5.6 1.8 8.8 4.1 2.4 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding eIF2A PF08662.6 AEO67885.1 - 5e-39 134.0 3.5 6.8e-37 127.0 0.3 3.8 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 AEO67885.1 - 0.00016 21.3 0.2 0.48 10.3 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat RRM_5 PF13893.1 AEO67885.1 - 0.0002 21.1 0.0 0.0005 19.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO67885.1 - 0.00027 20.8 0.0 0.00074 19.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO67885.1 - 0.00028 20.4 0.0 0.00063 19.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cpn60_TCP1 PF00118.19 AEO67886.1 - 1.6e-134 449.1 9.1 1.9e-134 448.9 6.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PAD_M PF08527.5 AEO67886.1 - 0.015 14.6 0.1 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain BID PF06393.6 AEO67887.1 - 0.026 13.8 0.1 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 BH3 interacting domain (BID) CENP-B_dimeris PF09026.5 AEO67887.1 - 3.7 7.8 11.1 9.6 6.5 7.7 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_M28 PF04389.12 AEO67889.1 - 3.7e-22 78.9 0.0 1.4e-21 76.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 AEO67889.1 - 1.7e-07 30.9 0.0 2.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Ank_2 PF12796.2 AEO67890.1 - 2.7e-24 85.3 0.2 6.3e-16 58.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 AEO67890.1 - 6.4e-21 73.9 7.1 8e-10 38.6 0.2 3.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 AEO67890.1 - 2.4e-20 71.2 7.4 5.4e-08 32.2 0.0 5.1 4 1 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 AEO67890.1 - 1.7e-16 60.2 0.4 5.4e-08 33.1 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO67890.1 - 4.6e-15 54.2 0.3 0.007 16.4 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat DUF4129 PF13559.1 AEO67890.1 - 5.6 6.9 7.4 6 6.9 0.4 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4129) FAD_binding_3 PF01494.14 AEO67891.1 - 7.7e-14 51.4 0.2 6.2e-09 35.3 0.1 2.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 AEO67891.1 - 1.6e-13 50.3 0.6 1.1e-05 24.5 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 AEO67891.1 - 1.3e-09 37.0 0.2 7.2e-09 34.6 0.1 1.9 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 AEO67891.1 - 2.2e-09 37.5 0.1 5.5e-09 36.2 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO67891.1 - 1.2e-08 34.2 0.2 1.2e-08 34.2 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 AEO67891.1 - 4.8e-06 26.5 0.1 1.7e-05 24.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 AEO67891.1 - 1.8e-05 25.0 0.3 0.048 14.0 0.1 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO67891.1 - 3.4e-05 23.1 0.1 7e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 AEO67891.1 - 3.4e-05 22.8 0.2 5.1e-05 22.3 0.1 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 AEO67891.1 - 4.7e-05 22.4 0.2 0.00012 21.1 0.1 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 AEO67891.1 - 0.00023 19.9 0.5 0.43 9.1 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 AEO67891.1 - 0.00025 21.1 0.1 0.00087 19.4 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO67891.1 - 0.0027 16.8 0.1 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_Gly3P_dh_N PF01210.18 AEO67891.1 - 0.072 12.8 0.1 3.7 7.2 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AP2 PF00847.15 AEO67891.1 - 0.3 11.2 2.3 0.29 11.3 0.2 2.0 2 0 0 2 2 2 0 AP2 domain SWIB PF02201.13 AEO67892.1 - 2.3e-26 91.2 0.4 1.2e-25 88.9 0.1 2.1 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 AEO67892.1 - 7.5e-15 54.4 2.0 1.6e-14 53.3 1.4 1.6 1 0 0 1 1 1 1 DEK C terminal domain DUF1762 PF08574.5 AEO67892.1 - 0.04 14.3 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1762) Myc_N PF01056.13 AEO67892.1 - 0.094 11.8 3.8 0.12 11.4 2.6 1.1 1 0 0 1 1 1 0 Myc amino-terminal region BTV_NS2 PF04514.7 AEO67892.1 - 0.82 8.4 5.8 1.5 7.6 4.0 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FLO_LFY PF01698.11 AEO67892.1 - 3.9 6.2 6.3 6.8 5.4 4.4 1.5 1 1 0 1 1 1 0 Floricaula / Leafy protein zf-C3HC4_3 PF13920.1 AEO67893.1 - 2e-06 27.3 9.2 2e-06 27.3 6.4 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO67893.1 - 0.00086 18.9 10.9 0.00086 18.9 7.6 2.7 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO67893.1 - 0.0053 16.7 11.8 0.0053 16.7 8.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO67893.1 - 0.013 15.1 11.6 0.013 15.1 8.0 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) GDE_C PF06202.9 AEO67894.1 - 0.0036 16.0 0.0 0.071 11.8 0.0 2.2 2 0 0 2 2 2 2 Amylo-alpha-1,6-glucosidase Sugar_tr PF00083.19 AEO67895.1 - 2.1e-69 234.2 18.7 2.6e-69 233.9 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO67895.1 - 6.1e-25 87.6 23.6 1.9e-22 79.4 11.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO67895.1 - 1.1e-05 24.1 3.0 1.1e-05 24.1 2.1 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein LacY_symp PF01306.14 AEO67895.1 - 0.0018 16.9 9.0 0.0025 16.4 0.1 2.8 2 1 0 2 2 2 1 LacY proton/sugar symporter HET PF06985.6 AEO67896.1 - 9e-22 77.7 0.0 1.5e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 AEO67897.1 - 9.9e-45 152.7 0.0 1.4e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 AEO67897.1 - 2.2e-44 150.4 0.0 3.7e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 AEO67897.1 - 3.1e-23 82.1 0.0 3.9e-22 78.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 AEO67897.1 - 7.1e-07 28.4 1.0 0.0011 18.4 0.0 2.9 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.1 AEO67897.1 - 1.6e-05 24.4 0.3 9.1e-05 22.0 0.2 1.8 1 1 0 1 1 1 1 PQQ-like domain Kdo PF06293.9 AEO67897.1 - 0.00071 18.7 0.0 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Acyl-CoA_dh_1 PF00441.19 AEO67898.1 - 5.2e-31 107.7 0.6 7.5e-31 107.2 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 AEO67898.1 - 1.1e-18 66.4 1.3 2.2e-18 65.5 0.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 AEO67898.1 - 1.9e-09 38.0 1.0 6.2e-09 36.4 0.7 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 AEO67898.1 - 6.8e-05 23.1 0.3 0.00012 22.3 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SprB PF13573.1 AEO67899.1 - 0.065 12.8 0.5 0.11 12.1 0.3 1.3 1 0 0 1 1 1 0 SprB repeat Porin_4 PF13609.1 AEO67899.1 - 0.11 11.9 1.4 0.14 11.6 1.0 1.1 1 0 0 1 1 1 0 Gram-negative porin DUF2397 PF09660.5 AEO67899.1 - 0.87 8.1 5.1 1.3 7.5 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) DUF605 PF04652.11 AEO67899.1 - 2.1 7.6 15.0 2.5 7.4 10.4 1.1 1 0 0 1 1 1 0 Vta1 like PepSY_2 PF13670.1 AEO67899.1 - 3.8 7.4 5.6 1.7 8.5 1.3 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Clr5 PF14420.1 AEO67900.1 - 6.7e-21 73.9 1.0 1.3e-20 72.9 0.7 1.5 1 0 0 1 1 1 1 Clr5 domain SR-25 PF10500.4 AEO67900.1 - 0.011 15.2 6.7 0.026 13.9 4.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SNF2_N PF00176.18 AEO67901.1 - 2.1e-10 39.9 0.0 0.00027 19.8 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO67901.1 - 0.0018 18.1 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain adh_short PF00106.20 AEO67902.1 - 7.8e-13 48.6 0.1 1.4e-12 47.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO67902.1 - 2.8e-12 46.9 0.0 3.4e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO67902.1 - 0.00019 21.1 0.2 0.00026 20.6 0.1 1.2 1 0 0 1 1 1 1 KR domain HNH_2 PF13391.1 AEO67903.1 - 2.8e-05 23.8 0.0 0.00013 21.6 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease MFS_1 PF07690.11 AEO67904.1 - 8.3e-30 103.6 26.9 8.3e-30 103.6 18.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily VIT1 PF01988.14 AEO67906.1 - 0.00069 19.1 0.0 0.00089 18.8 0.0 1.2 1 0 0 1 1 1 1 VIT family LRS4 PF10422.4 AEO67906.1 - 0.051 12.9 2.2 0.074 12.3 1.5 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF751 PF05421.6 AEO67906.1 - 0.15 12.3 4.0 0.21 11.8 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF751) Cellulase PF00150.13 AEO67907.1 - 9e-22 77.5 3.2 1.5e-21 76.8 2.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 AEO67907.1 - 2.3e-12 46.3 12.0 2.3e-12 46.3 8.3 3.3 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.12 AEO67907.1 - 0.00018 20.5 0.1 0.00041 19.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 AEO67907.1 - 0.0024 17.0 0.1 0.0075 15.4 0.1 1.7 2 0 0 2 2 2 1 Beta-galactosidase Cellulase-like PF12876.2 AEO67907.1 - 0.004 17.5 0.0 0.012 16.0 0.0 1.9 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_10 PF00331.15 AEO67907.1 - 0.0066 15.5 0.5 0.014 14.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 10 CTP_synth_N PF06418.9 AEO67908.1 - 3.8e-105 350.9 0.0 5.6e-105 350.3 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus Tannase PF07519.6 AEO67908.1 - 3.5e-87 293.1 0.0 1.6e-86 290.9 0.0 1.8 1 1 0 1 1 1 1 Tannase and feruloyl esterase GATase PF00117.23 AEO67908.1 - 1.2e-50 171.6 0.0 1.8e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AEO67908.1 - 0.0011 18.4 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 F-box-like PF12937.2 AEO67909.1 - 0.00038 20.1 1.1 0.00097 18.8 0.7 1.7 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.11 AEO67911.1 - 4e-39 134.3 64.0 1.8e-38 132.1 41.2 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO67911.1 - 5.9e-08 31.3 24.9 1.1e-07 30.4 17.2 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ESSS PF10183.4 AEO67911.1 - 6.5 7.2 11.1 13 6.2 0.3 4.0 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) NDUF_B8 PF05821.6 AEO67913.1 - 4.9e-06 26.3 0.1 6e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.18 AEO67914.1 - 3.2e-75 252.7 0.4 5.6e-75 251.9 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO67914.1 - 5.3e-14 51.8 0.0 1.3e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO67914.1 - 6.3e-09 35.9 0.0 1.3e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 AEO67914.1 - 9.3e-05 21.3 0.1 0.27 10.0 0.0 2.5 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 AEO67914.1 - 0.00021 20.8 0.0 0.0004 19.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 AEO67914.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 HSA PF07529.8 AEO67914.1 - 0.39 10.5 13.4 0.024 14.4 4.2 2.5 1 1 1 2 2 2 0 HSA CHORD PF04968.7 AEO67918.1 - 0.026 14.7 0.1 0.026 14.7 0.1 2.5 2 1 0 2 2 2 0 CHORD BTK PF00779.14 AEO67918.1 - 0.41 10.2 6.3 0.39 10.3 1.5 2.6 2 0 0 2 2 2 0 BTK motif NAD_binding_10 PF13460.1 AEO67920.1 - 3.3e-14 53.3 0.4 5.2e-14 52.6 0.3 1.4 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 AEO67920.1 - 3e-12 46.3 0.0 3.7e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 AEO67920.1 - 8.8e-10 38.0 0.0 1.2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 AEO67920.1 - 0.00047 19.6 0.0 0.0049 16.3 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 AEO67920.1 - 0.0013 19.1 0.2 0.0027 18.1 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 AEO67920.1 - 0.0035 17.2 0.1 0.007 16.2 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO67920.1 - 0.0066 16.1 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 KR domain GFO_IDH_MocA PF01408.17 AEO67920.1 - 0.011 16.2 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 AEO67920.1 - 0.015 15.6 0.1 0.033 14.4 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 AEO67920.1 - 0.035 14.0 0.1 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 AEO67920.1 - 0.13 12.0 0.5 0.3 10.9 0.3 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain GMC_oxred_N PF00732.14 AEO67921.1 - 1.3e-29 103.3 0.0 1.6e-28 99.7 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO67921.1 - 1.2e-27 96.9 0.0 2.9e-27 95.7 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 AEO67921.1 - 0.00066 19.6 0.1 0.0019 18.1 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO67921.1 - 0.0016 17.4 0.0 0.017 14.0 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 AEO67921.1 - 0.0019 17.1 1.1 0.4 9.5 0.2 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO67921.1 - 0.015 15.3 0.1 0.041 13.9 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 AEO67921.1 - 0.019 13.9 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HHH_5 PF14520.1 AEO67921.1 - 0.024 14.7 0.2 2.5 8.3 0.0 3.5 3 0 0 3 3 3 0 Helix-hairpin-helix domain FAD_binding_3 PF01494.14 AEO67921.1 - 0.041 12.9 0.0 0.092 11.7 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 AEO67921.1 - 0.13 11.0 0.1 0.35 9.6 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Abhydrolase_6 PF12697.2 AEO67922.1 - 1.5e-29 103.5 7.0 7.6e-29 101.2 4.9 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO67922.1 - 2.4e-06 27.3 0.0 4.7e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO67922.1 - 1.7e-05 24.6 0.0 3.2e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 AEO67922.1 - 0.0003 20.2 0.1 0.00052 19.5 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 AEO67922.1 - 0.012 14.8 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pkinase PF00069.20 AEO67923.1 - 2.7e-26 92.2 0.0 4.4e-26 91.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO67923.1 - 1.6e-05 24.1 0.0 2e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO67923.1 - 0.0078 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2101 PF09874.4 AEO67924.1 - 2.9 7.3 9.7 0.36 10.2 1.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) Myb_DNA-bind_6 PF13921.1 AEO67927.1 - 0.14 12.3 0.5 0.27 11.3 0.3 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-NADH-PPase PF09297.6 AEO67927.1 - 0.47 10.0 3.9 2.1 7.9 2.7 2.0 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Hydrolase_6 PF13344.1 AEO67928.1 - 2.8e-14 52.8 0.0 2.9e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AEO67928.1 - 0.011 16.1 0.0 0.012 16.0 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DEK_C PF08766.6 AEO67928.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 DEK C terminal domain HyaE PF07449.6 AEO67928.1 - 0.13 12.2 0.0 0.33 10.8 0.0 1.7 1 1 1 2 2 2 0 Hydrogenase-1 expression protein HyaE PSII_Ycf12 PF05969.6 AEO67929.1 - 0.17 11.5 4.1 0.71 9.5 2.9 2.1 1 0 0 1 1 1 0 Photosystem II complex subunit Ycf12 COesterase PF00135.23 AEO67930.1 - 6.5e-87 292.4 0.2 5.9e-79 266.1 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO67930.1 - 1.4e-13 50.9 0.4 2.3e-13 50.1 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO67930.1 - 0.00021 21.0 0.9 0.00049 19.8 0.3 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO67930.1 - 0.28 10.3 1.8 0.23 10.6 0.2 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Pheromone PF08015.6 AEO67932.1 - 0.019 15.8 3.3 0.019 15.8 2.3 4.5 4 1 0 4 4 4 0 Fungal mating-type pheromone GatB_N PF02934.10 AEO67933.1 - 1e-96 323.1 0.0 1.4e-96 322.8 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 AEO67933.1 - 2.9e-08 33.5 0.0 6.8e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 GatB domain Asp PF00026.18 AEO67934.1 - 4.4e-17 62.3 0.0 3.6e-15 56.0 0.0 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO67934.1 - 8e-06 25.8 0.1 3.5e-05 23.8 0.1 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO67934.1 - 0.0025 18.2 0.1 0.22 12.0 0.0 2.8 2 1 0 2 2 2 1 Aspartyl protease CRAL_TRIO PF00650.15 AEO67935.1 - 1.3e-14 54.0 0.0 1.9e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AEO67935.1 - 0.00037 20.5 0.0 0.001 19.1 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Mitofilin PF09731.4 AEO67935.1 - 0.77 8.3 14.7 0.98 7.9 10.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TFIIA PF03153.8 AEO67935.1 - 1.1 9.1 10.8 1.2 8.9 7.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit adh_short PF00106.20 AEO67936.1 - 2.2e-18 66.7 0.4 2.8e-18 66.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO67936.1 - 7.1e-10 38.8 0.1 8.8e-10 38.5 0.1 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO67936.1 - 5.6e-06 26.3 0.0 6.8e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AEO67936.1 - 8.3e-05 22.1 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO67936.1 - 0.00021 21.3 0.5 0.00039 20.4 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 AEO67936.1 - 0.014 14.7 0.1 0.018 14.3 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family FAD_binding_4 PF01565.18 AEO67938.1 - 1.1e-22 80.0 7.4 1.2e-22 79.9 2.3 2.6 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.7 AEO67938.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like CBM_1 PF00734.13 AEO67939.1 - 7.1e-15 54.3 11.4 1.8e-14 53.0 7.9 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Baculo_LEF5_C PF11792.3 AEO67940.1 - 0.11 11.9 1.5 0.29 10.5 1.0 1.7 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Cu_amine_oxid PF01179.15 AEO67942.1 - 9.6e-160 531.8 0.0 1.1e-159 531.6 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Myb_DNA-bind_6 PF13921.1 AEO67944.1 - 2.7e-17 62.5 16.0 5.4e-14 52.0 1.0 4.4 5 0 0 5 5 5 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO67944.1 - 1.2e-16 60.4 16.0 4.8e-10 39.3 0.4 4.4 5 0 0 5 5 5 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 AEO67944.1 - 0.079 13.0 7.4 0.038 14.1 0.6 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 AEO67944.1 - 0.22 11.7 3.6 4.7 7.4 0.1 3.5 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like AAA_16 PF13191.1 AEO67946.1 - 2.2e-06 27.8 1.5 8.6e-05 22.5 1.0 2.7 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 AEO67946.1 - 9.2e-05 22.2 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 AEO67946.1 - 0.0029 17.0 0.6 0.023 14.0 0.3 2.5 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 AEO67946.1 - 0.0087 16.2 0.1 0.023 14.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 AEO67946.1 - 0.062 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF3918 PF13056.1 AEO67946.1 - 0.066 12.5 0.1 0.18 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Miro PF08477.8 AEO67946.1 - 0.17 12.4 0.0 8.4 6.9 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein DUF3618 PF12277.3 AEO67946.1 - 0.2 11.7 2.0 5 7.2 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Fungal_trans_2 PF11951.3 AEO67947.1 - 9.9e-32 109.9 0.0 1.2e-17 63.5 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO67947.1 - 2e-08 33.9 11.5 3.3e-08 33.3 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSDC PF12588.3 AEO67948.1 - 4.6e-48 162.4 0.0 6.6e-48 161.9 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 AEO67948.1 - 1.3e-34 119.2 0.0 2.2e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 AEO67948.1 - 0.001 18.7 0.0 0.44 10.2 0.0 2.6 2 0 0 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.1 AEO67948.1 - 0.12 12.1 0.0 15 5.3 0.0 2.6 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain DsrD PF08679.6 AEO67948.1 - 0.19 11.7 0.2 0.63 10.0 0.1 1.9 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) zf-C2H2_3 PF13878.1 AEO67949.1 - 4.8e-06 26.0 0.1 1.2e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO Vma12 PF11712.3 AEO67950.1 - 2e-40 137.7 0.0 2.6e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1469 PF07332.6 AEO67950.1 - 0.29 10.8 3.4 0.46 10.2 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) polyprenyl_synt PF00348.12 AEO67951.1 - 3.8e-55 186.5 0.1 3.6e-51 173.5 0.0 2.2 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 AEO67951.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 ADH_zinc_N PF00107.21 AEO67952.1 - 6.6e-23 80.6 0.7 9.7e-23 80.1 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO67952.1 - 9.7e-08 32.9 0.2 2.9e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Aldo_ket_red PF00248.16 AEO67952.1 - 0.065 12.0 0.0 0.095 11.5 0.0 1.1 1 0 0 1 1 1 0 Aldo/keto reductase family AlaDh_PNT_C PF01262.16 AEO67952.1 - 0.082 12.4 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PhoH PF02562.11 AEO67952.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Amidohydro_1 PF01979.15 AEO67953.1 - 2.6e-20 73.3 1.5 7.2e-11 42.3 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 AEO67953.1 - 1.6e-17 64.4 9.7 3.8e-16 59.9 6.7 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 AEO67953.1 - 1.1e-09 38.0 0.5 3.2e-06 26.6 0.1 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 AEO67953.1 - 1.2e-09 37.8 0.0 2.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase PIP5K PF01504.13 AEO67954.1 - 2.2e-87 292.3 0.1 3.1e-87 291.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase COX6B PF02297.12 AEO67955.1 - 3.2e-20 71.9 0.6 4.1e-20 71.5 0.4 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb SYS1 PF09801.4 AEO67956.1 - 3.9e-49 166.3 1.5 4.5e-49 166.1 1.1 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network CHD5 PF04420.9 AEO67956.1 - 0.016 14.8 0.3 0.022 14.4 0.2 1.2 1 0 0 1 1 1 0 CHD5-like protein TrbE PF11100.3 AEO67956.1 - 0.16 11.8 1.0 0.32 10.8 0.6 1.6 1 1 0 1 1 1 0 Conjugal transfer protein TrbE Acyl-CoA_dh_1 PF00441.19 AEO67957.1 - 5.3e-25 88.2 0.7 9.3e-25 87.4 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 AEO67957.1 - 1.9e-24 86.4 0.2 4.6e-24 85.1 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 AEO67957.1 - 1.7e-14 53.0 0.0 7.1e-14 51.0 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 AEO67957.1 - 7.6e-08 32.6 1.1 1.3e-07 31.9 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 AEO67957.1 - 0.13 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal UQ_con PF00179.21 AEO67958.1 - 4.5e-53 178.4 0.0 5.1e-53 178.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO67958.1 - 0.00025 20.7 0.0 0.0003 20.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AEO67958.1 - 0.0013 18.5 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 AEO67958.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain NAD_binding_6 PF08030.7 AEO67959.1 - 9.2e-33 113.3 0.0 1.6e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 AEO67959.1 - 3e-22 78.4 0.0 9.6e-22 76.8 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 AEO67959.1 - 1.1e-17 64.2 17.6 1.3e-16 60.8 6.9 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 AEO67959.1 - 2.4e-05 24.3 0.0 5.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 AEO67959.1 - 0.12 12.9 0.0 0.75 10.3 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain XPG_I PF00867.13 AEO67960.1 - 8.1e-31 105.9 0.0 1.9e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 AEO67960.1 - 6.6e-19 68.0 0.0 2.2e-18 66.3 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 AEO67960.1 - 2e-05 24.7 0.5 0.00014 22.0 0.0 2.5 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold TniB PF05621.6 AEO67960.1 - 0.051 12.3 0.0 0.072 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Acyl-CoA_dh_1 PF00441.19 AEO67961.1 - 1.9e-41 141.6 0.6 2.6e-41 141.1 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 AEO67961.1 - 2.8e-21 74.7 0.2 5.2e-21 73.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 AEO67961.1 - 5e-20 71.0 0.1 8.5e-20 70.3 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 AEO67961.1 - 4.5e-18 65.8 0.0 1.1e-17 64.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 AEO67961.1 - 3.3e-08 33.8 0.0 1.3e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Cys_rich_VLP PF14194.1 AEO67961.1 - 0.037 13.7 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 Cysteine-rich VLP Tim17 PF02466.14 AEO67962.1 - 2.6e-12 46.8 2.7 4.8e-12 46.0 1.9 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2231 PF09990.4 AEO67962.1 - 0.0024 18.1 0.4 0.0052 17.0 0.3 1.6 1 1 0 1 1 1 1 Predicted membrane protein (DUF2231) DUF606 PF04657.8 AEO67962.1 - 0.07 13.2 1.8 0.096 12.7 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF606 UCH PF00443.24 AEO67963.1 - 3.7e-13 49.2 0.0 9.8e-13 47.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 AEO67963.1 - 1.6e-09 37.0 0.0 0.023 14.0 0.0 3.7 3 0 0 3 3 3 3 A repeated domain in UCH-protein UCH_1 PF13423.1 AEO67963.1 - 5.6e-07 29.2 0.2 0.00054 19.4 0.4 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.5 AEO67963.1 - 0.00056 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 PUB domain MutS_V PF00488.16 AEO67964.1 - 2.8e-98 328.0 0.0 4.2e-98 327.4 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AEO67964.1 - 4.3e-41 140.9 1.1 1.1e-40 139.6 0.8 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 AEO67964.1 - 6e-20 71.7 0.5 1.8e-19 70.1 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.15 AEO67964.1 - 1.9e-18 66.5 0.0 9.9e-18 64.2 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 AEO67964.1 - 1.6e-17 63.4 0.4 1.6e-17 63.4 0.3 2.9 4 0 0 4 4 4 1 MutS family domain IV Peptidase_M16 PF00675.15 AEO67964.1 - 0.042 13.5 0.2 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) AAA_22 PF13401.1 AEO67964.1 - 0.084 13.0 0.1 1 9.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain tRNA_m1G_MT PF01746.16 AEO67965.1 - 2e-30 105.7 1.8 1.1e-22 80.4 0.0 2.7 3 0 0 3 3 3 2 tRNA (Guanine-1)-methyltransferase NARP1 PF12569.3 AEO67965.1 - 0.35 9.5 9.8 0.71 8.5 6.8 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Hex_IIIa PF02455.11 AEO67965.1 - 7 5.2 7.6 12 4.4 5.3 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DNA_primase_S PF01896.14 AEO67966.1 - 5.2e-55 185.2 0.0 9.1e-55 184.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Cellulase PF00150.13 AEO67967.1 - 7.5e-14 51.5 2.7 4.4e-08 32.6 0.6 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 AEO67967.1 - 0.053 12.6 0.3 5.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Beta-galactosidase MFS_1 PF07690.11 AEO67968.1 - 2.6e-47 161.2 53.0 1.9e-40 138.7 23.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.14 AEO67968.1 - 5.7e-05 21.8 0.3 0.00057 18.5 0.0 2.3 2 0 0 2 2 2 1 LacY proton/sugar symporter Haem_oxygenas_2 PF14518.1 AEO67969.1 - 1.8e-06 28.0 0.0 3.5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Iron-containing redox enzyme Arginosuc_synth PF00764.14 AEO67969.1 - 0.0016 17.5 0.3 0.0023 17.0 0.2 1.1 1 0 0 1 1 1 1 Arginosuccinate synthase Pkinase PF00069.20 AEO67970.1 - 4.8e-66 222.5 0.0 7.5e-66 221.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO67970.1 - 7.3e-49 166.1 0.0 1.2e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO67970.1 - 6.7e-09 35.1 0.0 7.2e-07 28.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 AEO67970.1 - 0.0099 14.9 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_47 PF01532.15 AEO67971.1 - 1.6e-174 580.8 0.0 3e-174 579.9 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 Fig1 PF12351.3 AEO67972.1 - 1.1e-56 191.5 4.8 1.1e-56 191.5 3.3 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 AEO67972.1 - 1.1e-08 34.8 8.9 1.5e-08 34.4 6.2 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 AEO67972.1 - 0.00086 18.2 6.7 0.00086 18.2 4.7 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF202 PF02656.10 AEO67972.1 - 0.28 11.4 10.5 0.3 11.3 0.4 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF202) MLTD_N PF06474.7 AEO67972.1 - 2 8.6 6.4 1.5 9.0 1.9 2.5 2 0 0 2 2 2 0 MltD lipid attachment motif ODV-E18 PF10717.4 AEO67972.1 - 4.6 6.7 11.3 0.91 9.0 0.8 3.3 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 DUF4131 PF13567.1 AEO67972.1 - 6.3 6.1 14.1 0.11 11.8 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) APH PF01636.18 AEO67973.1 - 1.3e-05 25.0 0.2 3.5e-05 23.6 0.2 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO67973.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase DSBA PF01323.15 AEO67974.1 - 2.3e-42 144.7 0.0 2.6e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 AEO67974.1 - 8.8e-06 25.8 0.0 2.6e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 AEO67974.1 - 0.00057 19.6 0.0 0.066 13.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin domain DASH_Spc34 PF08657.5 AEO67975.1 - 4.7e-51 173.9 0.0 5.2e-50 170.5 0.0 1.9 1 1 0 1 1 1 1 DASH complex subunit Spc34 Sporozoite_P67 PF05642.6 AEO67976.1 - 0.5 8.1 7.1 0.78 7.5 4.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFIID_20kDa PF03847.8 AEO67977.1 - 5.2e-18 65.0 0.0 8.9e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Pex16 PF08610.5 AEO67977.1 - 0.1 11.6 4.1 0.3 10.0 2.8 1.8 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Mod_r PF07200.8 AEO67977.1 - 2.8 7.8 25.3 0.17 11.7 2.3 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2284 PF10050.4 AEO67977.1 - 2.9 7.4 4.2 1.2 8.6 0.5 1.9 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) Band_3_cyto PF07565.8 AEO67977.1 - 3.7 6.9 9.1 3.6 7.0 3.8 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Rpn3_C PF08375.6 AEO67978.1 - 2.9e-24 85.2 1.4 2.9e-24 85.2 1.0 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 AEO67978.1 - 5.4e-20 71.6 0.4 3.7e-19 68.9 0.0 2.5 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.12 AEO67978.1 - 0.016 15.0 0.1 0.049 13.5 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-RING_2 PF13639.1 AEO67979.1 - 7.8e-09 35.2 12.7 1.3e-08 34.5 8.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO67979.1 - 6.7e-07 29.2 8.6 1.1e-06 28.5 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO67979.1 - 5.2e-06 26.0 7.6 8.3e-06 25.3 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO67979.1 - 5.8e-06 25.8 8.1 8.9e-06 25.2 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO67979.1 - 0.00087 19.3 11.1 0.0024 17.9 7.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger Drc1-Sld2 PF11719.3 AEO67980.1 - 3.9e-62 210.7 21.9 5.5e-62 210.2 15.2 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein DNA_methylase PF00145.12 AEO67982.1 - 3.2e-33 115.2 0.0 1.2e-25 90.4 0.0 2.1 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase BAH PF01426.13 AEO67982.1 - 9.1e-06 25.4 0.0 0.02 14.6 0.0 2.6 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.3 AEO67982.1 - 0.028 14.0 0.1 0.066 12.9 0.1 1.5 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain MOZ_SAS PF01853.13 AEO67983.1 - 2.9e-47 160.3 0.0 5.1e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family ATP-synt_C PF00137.16 AEO67984.1 - 5.5e-10 38.9 7.3 1.2e-09 37.9 5.1 1.6 1 0 0 1 1 1 1 ATP synthase subunit C Inhibitor_I36 PF03995.8 AEO67984.1 - 0.034 14.5 0.0 0.052 13.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase inhibitor family I36 iPGM_N PF06415.8 AEO67985.1 - 2.8e-74 249.2 0.0 3.8e-74 248.7 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 AEO67985.1 - 1.6e-69 234.1 0.0 1.8e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 AEO67985.1 - 1.4e-06 27.9 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 AEO67985.1 - 9.5e-06 25.0 0.0 0.00017 20.8 0.0 2.3 1 1 0 1 1 1 1 Sulfatase Med9 PF07544.8 AEO67986.1 - 4.5e-10 39.1 0.0 9.1e-10 38.1 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DUF605 PF04652.11 AEO67986.1 - 0.52 9.6 21.1 0.63 9.3 14.6 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 AEO67986.1 - 2 8.2 11.9 2.2 8.0 8.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TBCC PF07986.7 AEO67987.1 - 2.5e-30 104.3 0.0 4.1e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF3580 PF12117.3 AEO67987.1 - 1.4 8.9 5.6 0.48 10.3 1.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3580) DUF1180 PF06679.7 AEO67987.1 - 1.5 8.6 6.0 2.9 7.7 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Gpi1 PF05024.10 AEO67988.1 - 3.6e-66 222.4 7.6 3.6e-66 222.4 5.3 2.0 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) 7tm_1 PF00001.16 AEO67988.1 - 0.00018 20.7 0.0 0.00032 19.9 0.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Tom37_C PF11801.3 AEO67988.1 - 0.16 11.8 3.0 5.1 6.9 0.4 3.1 3 0 0 3 3 3 0 Tom37 C-terminal domain DUF3333 PF11812.3 AEO67988.1 - 0.19 11.7 0.7 0.33 10.9 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) UPF0203 PF05254.7 AEO67989.1 - 2.8e-26 91.1 1.3 3.6e-26 90.7 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 AEO67989.1 - 0.0021 17.7 4.1 0.097 12.4 0.1 2.6 1 1 2 3 3 3 3 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 AEO67989.1 - 0.01 15.8 0.5 0.05 13.6 0.3 2.0 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) COX6B PF02297.12 AEO67989.1 - 2.6 8.1 7.3 3.1 7.8 0.9 2.2 1 1 0 2 2 2 0 Cytochrome oxidase c subunit VIb DNA_pol_A_exo1 PF01612.15 AEO67990.1 - 1.5e-40 138.5 0.4 2.3e-40 137.9 0.3 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 AEO67990.1 - 2.4e-26 91.8 0.1 5.9e-26 90.5 0.1 1.7 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 AEO67990.1 - 2.1e-14 52.9 0.0 5.2e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 HRDC domain Asp PF00026.18 AEO67991.1 - 1.1e-110 369.8 0.1 1.3e-110 369.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO67991.1 - 1.4e-12 47.9 0.1 6e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO67991.1 - 1.2e-06 28.9 0.3 0.044 14.2 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 AEO67991.1 - 0.00081 18.9 0.0 0.0056 16.2 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Prefoldin PF02996.12 AEO67992.1 - 6.4e-36 122.6 0.0 9.5e-36 122.0 0.0 1.3 1 0 0 1 1 1 1 Prefoldin subunit HR1 PF02185.11 AEO67992.1 - 0.0048 16.6 0.2 0.046 13.4 0.0 2.2 2 0 0 2 2 2 1 Hr1 repeat Filament PF00038.16 AEO67992.1 - 0.0076 15.7 0.6 0.93 8.8 0.0 2.0 2 0 0 2 2 2 2 Intermediate filament protein Prefoldin_2 PF01920.15 AEO67992.1 - 0.012 15.3 3.8 0.045 13.5 0.0 2.6 3 0 0 3 3 3 0 Prefoldin subunit DUF2353 PF09789.4 AEO67992.1 - 0.093 11.9 2.0 0.22 10.7 1.4 1.6 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) KLRAQ PF10205.4 AEO67992.1 - 0.13 12.2 1.7 1.5 8.8 0.1 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4201 PF13870.1 AEO67992.1 - 0.24 10.7 3.0 0.38 10.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) SlyX PF04102.7 AEO67992.1 - 0.52 10.7 3.1 4.9 7.6 0.1 2.7 3 0 0 3 3 3 0 SlyX CRAL_TRIO PF00650.15 AEO67993.1 - 6.4e-37 126.4 0.0 9.5e-37 125.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AEO67993.1 - 9.4e-10 38.4 1.3 4.1e-09 36.4 0.2 2.5 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AEO67993.1 - 0.00047 20.0 0.0 0.0023 17.8 0.0 1.9 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Mis14 PF08641.7 AEO67994.1 - 2.7e-05 24.2 0.6 4e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Kinetochore protein Mis14 like CALCOCO1 PF07888.6 AEO67994.1 - 0.085 11.1 0.2 0.13 10.5 0.0 1.3 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like SR-25 PF10500.4 AEO67995.1 - 0.06 12.8 5.9 0.084 12.3 4.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 AEO67995.1 - 1.5 8.1 4.2 1.9 7.8 2.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RVT_1 PF00078.22 AEO67996.1 - 0.055 12.8 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AAA PF00004.24 AEO67997.1 - 1.5e-45 154.6 0.5 5e-45 152.9 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AEO67997.1 - 6.9e-09 35.5 0.4 2.9e-08 33.5 0.1 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AEO67997.1 - 3.9e-08 33.4 0.0 8.1e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 AEO67997.1 - 4.6e-07 29.9 0.0 1.5e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AEO67997.1 - 6.8e-07 29.4 0.6 0.001 19.1 0.0 2.8 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 AEO67997.1 - 2.6e-06 26.5 0.0 5.8e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 AEO67997.1 - 0.00018 21.3 0.0 0.00073 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AEO67997.1 - 0.00037 19.6 0.0 0.00086 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 AEO67997.1 - 0.0004 20.3 0.0 0.00081 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO67997.1 - 0.00062 20.5 0.1 0.0023 18.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 AEO67997.1 - 0.00065 19.4 1.4 0.059 13.0 0.0 3.3 3 1 0 4 4 4 1 NACHT domain Zeta_toxin PF06414.7 AEO67997.1 - 0.0011 18.1 0.1 0.0038 16.3 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin TIP49 PF06068.8 AEO67997.1 - 0.0011 17.7 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 AEO67997.1 - 0.0013 18.4 0.2 0.0035 17.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 AEO67997.1 - 0.0018 18.4 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 AEO67997.1 - 0.0031 17.2 0.0 0.01 15.5 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_3 PF07726.6 AEO67997.1 - 0.0037 16.8 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 AEO67997.1 - 0.0043 16.6 0.4 0.016 14.7 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_23 PF13476.1 AEO67997.1 - 0.0046 17.3 0.2 0.83 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AEO67997.1 - 0.0049 16.7 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 AEO67997.1 - 0.0054 16.3 0.0 0.043 13.4 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 AEO67997.1 - 0.0065 15.6 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 AEO67997.1 - 0.0075 15.9 0.5 0.059 13.0 0.0 2.5 2 1 1 3 3 3 1 Archaeal ATPase AAA_30 PF13604.1 AEO67997.1 - 0.0077 15.8 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AEO67997.1 - 0.0089 15.4 0.6 0.024 14.0 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 AEO67997.1 - 0.0097 16.2 0.0 0.028 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 AEO67997.1 - 0.011 15.3 0.5 0.03 13.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 AEO67997.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.1 AEO67997.1 - 0.021 14.2 3.0 0.069 12.5 0.1 2.6 2 1 1 3 3 3 0 AAA domain Viral_Hsp90 PF03225.9 AEO67997.1 - 0.027 12.7 0.0 0.044 12.0 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue KaiC PF06745.8 AEO67997.1 - 0.034 13.2 1.0 0.45 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.21 AEO67997.1 - 0.048 13.1 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.11 AEO67997.1 - 0.054 12.2 0.0 0.13 11.0 0.0 1.6 2 0 0 2 2 2 0 AFG1-like ATPase Cast PF10174.4 AEO67997.1 - 0.055 11.5 2.2 0.096 10.7 0.9 1.7 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Sigma54_activ_2 PF14532.1 AEO67997.1 - 0.061 13.3 0.1 0.35 10.9 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 AEO67997.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 AEO67997.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Folliculin PF11704.3 AEO67998.1 - 3.7e-25 88.4 0.0 1.2e-24 86.7 0.0 1.9 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Y_phosphatase PF00102.22 AEO67999.1 - 7.3e-47 159.6 0.0 3.8e-38 131.1 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 AEO67999.1 - 0.0019 18.2 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 AEO67999.1 - 0.017 14.7 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 AEO67999.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family RCC1 PF00415.13 AEO68000.1 - 2.7e-31 107.5 3.8 4.6e-06 26.7 0.0 7.2 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AEO68000.1 - 2.1e-14 52.6 24.8 3.9e-09 35.8 0.0 7.5 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Sec34 PF04136.10 AEO68002.1 - 2.2e-31 108.6 0.2 4.4e-31 107.7 0.1 1.4 1 0 0 1 1 1 1 Sec34-like family IncA PF04156.9 AEO68002.1 - 0.0038 16.8 3.3 0.0038 16.8 2.3 1.9 2 0 0 2 2 2 1 IncA protein Mito_carr PF00153.22 AEO68003.1 - 2.2e-55 184.3 9.9 4e-22 77.7 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein RINT1_TIP1 PF04437.8 AEO68004.1 - 4.2e-98 329.0 0.0 5.7e-98 328.6 0.0 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family ALIX_LYPXL_bnd PF13949.1 AEO68004.1 - 0.018 14.0 5.2 0.043 12.7 3.6 1.6 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV ADIP PF11559.3 AEO68004.1 - 0.022 14.6 4.1 0.071 13.0 2.9 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding COG2 PF06148.6 AEO68004.1 - 0.06 13.2 0.5 0.34 10.7 0.3 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Myosin_tail_1 PF01576.14 AEO68004.1 - 0.12 10.0 10.6 0.014 13.1 3.5 1.8 2 0 0 2 2 2 0 Myosin tail TPR_MLP1_2 PF07926.7 AEO68004.1 - 0.18 11.5 9.7 0.052 13.2 2.2 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 AEO68004.1 - 9.2 5.8 15.1 33 4.0 10.4 1.9 1 1 0 1 1 1 0 IncA protein DUF155 PF02582.9 AEO68005.1 - 5.9e-42 143.5 0.0 8.5e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SHMT PF00464.14 AEO68008.1 - 1.2e-211 702.1 0.0 1.4e-211 701.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 AEO68008.1 - 0.00029 20.0 0.0 0.00085 18.5 0.0 1.8 1 1 1 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.14 AEO68008.1 - 0.00084 18.1 0.0 0.0014 17.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Bromodomain PF00439.20 AEO68009.1 - 8.4e-20 70.4 0.4 2.1e-19 69.2 0.3 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 AEO68009.1 - 1e-09 37.9 0.0 3.8e-09 36.1 0.0 2.0 1 1 0 1 1 1 1 Bromodomain associated VanZ PF04892.7 AEO68010.1 - 2.7e-13 50.0 1.8 3.6e-13 49.6 1.3 1.2 1 0 0 1 1 1 1 VanZ like family DUF4401 PF14351.1 AEO68010.1 - 0.0032 16.4 0.7 0.0046 15.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) NAD_binding_6 PF08030.7 AEO68011.1 - 7.2e-17 61.7 0.0 1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 AEO68011.1 - 2.9e-16 59.6 12.3 2.9e-16 59.6 8.5 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 AEO68011.1 - 3.5e-06 27.5 0.1 0.076 13.5 0.0 2.3 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.7 AEO68011.1 - 8e-05 22.4 0.0 0.00042 20.1 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain VWA_CoxE PF05762.9 AEO68011.1 - 0.031 13.4 0.6 0.068 12.2 0.4 1.6 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Glycos_transf_4 PF00953.16 AEO68011.1 - 0.18 11.6 4.2 0.32 10.7 2.9 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 4 Git3 PF11710.3 AEO68012.1 - 1.7e-17 63.6 12.7 4.9e-17 62.1 8.8 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 AEO68012.1 - 1.4e-11 44.0 4.0 1.6e-11 43.8 2.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 AEO68012.1 - 1.6e-07 31.0 0.1 1.6e-07 31.0 0.0 2.4 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term LETM1 PF07766.8 AEO68013.1 - 6.4e-11 41.7 1.7 9.9e-10 37.8 0.2 2.1 2 0 0 2 2 2 2 LETM1-like protein B12-binding PF02310.14 AEO68013.1 - 0.05 13.4 0.2 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 B12 binding domain Spc7_N PF15402.1 AEO68013.1 - 4.2 5.2 7.1 6 4.7 4.9 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 RRM_1 PF00076.17 AEO68014.1 - 1.2e-08 34.4 0.0 1.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO68014.1 - 3e-05 23.8 0.0 5.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO68014.1 - 0.009 15.8 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.15 AEO68015.1 - 1.7e-13 50.3 0.7 2.3e-13 49.9 0.5 1.2 1 0 0 1 1 1 1 RF-1 domain GNAT_acetyltr_2 PF13718.1 AEO68016.1 - 7e-81 270.2 0.0 1.1e-80 269.5 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 AEO68016.1 - 5.8e-65 218.2 0.0 2.2e-64 216.3 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 AEO68016.1 - 6.1e-40 134.8 0.1 1.4e-39 133.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 AEO68016.1 - 5.5e-34 116.3 0.6 1.8e-33 114.6 0.4 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_22 PF13401.1 AEO68016.1 - 0.0047 17.0 0.1 0.26 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain Acetyltransf_7 PF13508.1 AEO68016.1 - 0.0056 16.8 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.20 AEO68017.1 - 1.8e-68 230.4 0.0 2.3e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO68017.1 - 2.8e-29 101.9 0.0 3.7e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO68017.1 - 1.1e-06 27.8 0.0 1.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AEO68017.1 - 0.00024 20.2 0.0 0.00042 19.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO68017.1 - 0.00056 19.7 0.1 0.00056 19.7 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 AEO68017.1 - 0.024 13.9 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF605 PF04652.11 AEO68017.1 - 0.25 10.7 22.7 0.37 10.1 15.8 1.2 1 0 0 1 1 1 0 Vta1 like PAP2 PF01569.16 AEO68018.1 - 4.5e-14 52.2 3.8 4.5e-14 52.2 2.7 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 AEO68018.1 - 2.1e-08 33.9 7.5 6e-08 32.4 5.2 1.8 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 AEO68018.1 - 1.3 9.3 7.0 0.62 10.3 1.4 2.6 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Clp1 PF06807.9 AEO68022.1 - 0.004 16.9 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 AEO68022.1 - 0.0047 16.6 0.0 0.0089 15.7 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 AEO68022.1 - 0.014 16.2 0.0 0.025 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AEO68022.1 - 0.017 15.4 0.0 0.076 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 AEO68022.1 - 0.039 13.8 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Glyco_hydro_61 PF03443.9 AEO68023.1 - 3.2e-59 200.3 0.1 5.2e-59 199.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 AEO68023.1 - 9.2e-14 50.8 12.9 4e-13 48.7 8.9 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain MFS_1 PF07690.11 AEO68025.1 - 3.9e-40 137.6 33.8 5.5e-40 137.1 23.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_3 PF00933.16 AEO68026.1 - 3.8e-83 278.9 0.0 1.6e-78 263.7 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO68026.1 - 2.3e-55 187.5 0.1 4.7e-55 186.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO68026.1 - 2.9e-16 59.1 0.1 6.9e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Lgl_C PF08596.5 AEO68027.1 - 2.1e-118 395.2 0.0 3e-118 394.7 0.0 1.2 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 AEO68027.1 - 0.0022 17.8 10.6 0.2 11.6 0.1 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat PQQ_2 PF13360.1 AEO68027.1 - 0.019 14.4 0.3 7.1 6.0 0.0 3.2 3 1 0 3 3 3 0 PQQ-like domain Piwi PF02171.12 AEO68028.1 - 2.9e-77 259.6 0.0 5.1e-77 258.8 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 AEO68028.1 - 4.1e-13 48.8 0.1 1.1e-12 47.4 0.1 1.7 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 AEO68028.1 - 1.3e-07 30.8 0.0 2.6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Suf PF05843.9 AEO68029.1 - 6.4e-86 288.5 11.2 7.1e-85 285.1 0.0 3.9 4 2 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 AEO68029.1 - 7.7e-05 23.2 2.3 0.00051 20.6 0.1 3.3 2 2 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 AEO68029.1 - 0.00079 19.8 4.9 0.0028 18.1 1.0 3.9 4 1 1 5 5 5 1 Tetratricopeptide repeat HAT PF02184.11 AEO68029.1 - 0.0024 17.6 0.1 0.056 13.1 0.0 2.6 2 0 0 2 2 2 1 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 AEO68029.1 - 0.0045 17.2 0.1 0.15 12.4 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 AEO68029.1 - 0.042 14.3 2.4 0.24 11.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 AEO68029.1 - 0.098 12.5 0.5 17 5.5 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat ASF1_hist_chap PF04729.8 AEO68030.1 - 3.3e-67 224.9 0.0 4.4e-67 224.5 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nrap PF03813.9 AEO68031.1 - 0 1121.9 0.0 0 1121.7 0.0 1.0 1 0 0 1 1 1 1 Nrap protein TPR_11 PF13414.1 AEO68032.1 - 2.5e-45 151.9 47.3 7.9e-09 35.0 0.0 12.2 9 3 4 13 13 13 11 TPR repeat TPR_16 PF13432.1 AEO68032.1 - 1.1e-40 137.5 65.5 1.6e-07 31.7 0.1 14.1 12 3 2 14 14 13 8 Tetratricopeptide repeat TPR_14 PF13428.1 AEO68032.1 - 4.9e-31 104.3 54.0 0.00028 21.2 0.0 16.6 12 6 6 18 18 17 8 Tetratricopeptide repeat TPR_2 PF07719.12 AEO68032.1 - 9.2e-30 100.1 51.0 0.00019 21.1 0.0 16.5 16 0 0 16 16 15 8 Tetratricopeptide repeat TPR_19 PF14559.1 AEO68032.1 - 2.3e-29 101.4 34.6 2e-05 24.8 0.3 11.5 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.23 AEO68032.1 - 2.7e-25 86.8 38.1 1.2e-05 24.7 0.0 14.4 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_17 PF13431.1 AEO68032.1 - 9.8e-23 78.4 21.2 0.12 12.6 0.0 15.5 18 0 0 18 18 16 5 Tetratricopeptide repeat TPR_12 PF13424.1 AEO68032.1 - 2.3e-21 75.5 50.3 0.00028 20.7 0.1 13.5 9 4 5 14 14 14 6 Tetratricopeptide repeat TPR_8 PF13181.1 AEO68032.1 - 4e-19 66.9 30.1 0.028 14.1 0.0 14.2 13 2 2 15 15 15 4 Tetratricopeptide repeat TPR_7 PF13176.1 AEO68032.1 - 2.5e-13 48.7 33.0 0.012 15.3 0.0 14.2 14 0 0 14 14 14 3 Tetratricopeptide repeat TPR_6 PF13174.1 AEO68032.1 - 1.7e-11 43.7 39.1 0.098 13.1 0.0 14.1 15 0 0 15 15 13 2 Tetratricopeptide repeat Apc3 PF12895.2 AEO68032.1 - 1.9e-05 24.6 26.3 0.035 14.2 0.0 8.8 8 1 1 9 9 9 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AEO68032.1 - 4e-05 23.3 24.7 0.0011 18.7 0.1 9.5 9 2 1 10 10 10 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AEO68032.1 - 0.00048 19.9 4.5 1.7 8.5 0.1 5.9 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.5 AEO68032.1 - 0.0031 16.3 3.9 5.6 5.6 0.0 4.7 5 0 0 5 5 5 1 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_WDAD PF04053.9 AEO68032.1 - 0.022 13.5 0.0 0.041 12.6 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region Endonuc-FokI_C PF09254.6 AEO68032.1 - 0.13 11.3 0.3 0.24 10.4 0.2 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal FlgN PF05130.7 AEO68032.1 - 0.15 12.3 0.1 0.15 12.3 0.1 2.6 3 0 0 3 3 2 0 FlgN protein TPR_20 PF14561.1 AEO68032.1 - 0.91 9.6 25.7 4.2 7.5 0.0 7.6 8 2 0 8 8 7 0 Tetratricopeptide repeat DUF1767 PF08585.7 AEO68033.1 - 3.3e-06 27.2 0.0 5.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Vps51 PF08700.6 AEO68034.1 - 5.3e-22 77.4 0.1 7.6e-22 76.9 0.0 1.2 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 AEO68034.1 - 0.0042 15.6 0.7 0.0054 15.2 0.5 1.1 1 0 0 1 1 1 1 Dor1-like family Fes1 PF08609.5 AEO68034.1 - 0.056 13.9 0.0 0.11 12.9 0.0 1.5 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 DUF605 PF04652.11 AEO68034.1 - 0.36 10.1 14.4 0.43 9.9 10.0 1.1 1 0 0 1 1 1 0 Vta1 like NIF3 PF01784.13 AEO68035.1 - 1.2e-59 201.7 0.0 1.5e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF3280 PF11684.3 AEO68035.1 - 0.058 13.5 0.0 0.098 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2380) BolA PF01722.13 AEO68036.1 - 8.6e-22 76.8 0.0 1.1e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Pkinase PF00069.20 AEO68037.1 - 1.9e-22 79.6 0.0 1.1e-21 77.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO68037.1 - 0.0036 16.4 0.0 0.038 13.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase CPSF100_C PF13299.1 AEO68038.1 - 1e-41 142.8 0.0 4.7e-41 140.6 0.0 2.0 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 AEO68038.1 - 1.7e-28 99.0 0.0 7e-28 97.0 0.0 2.0 1 1 1 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 AEO68038.1 - 1.7e-07 30.8 0.0 3.8e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 AEO68038.1 - 4.6e-05 23.1 0.4 0.00015 21.4 0.3 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AEO68038.1 - 0.002 17.7 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sec23_trunk PF04811.10 AEO68039.1 - 5.2e-54 183.1 0.0 7e-53 179.4 0.0 2.4 2 1 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 AEO68039.1 - 4.5e-23 80.6 0.2 7.9e-23 79.8 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 AEO68039.1 - 3.1e-18 66.0 0.0 5.7e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 AEO68039.1 - 1e-17 63.4 4.2 2.2e-17 62.3 2.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 AEO68039.1 - 2.2e-05 24.0 0.0 4.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF2263 PF10021.4 AEO68040.1 - 5.7e-13 49.1 0.0 1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) tRNA-synt_2 PF00152.15 AEO68042.1 - 4.9e-68 229.3 0.0 5.8e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 AEO68042.1 - 0.049 12.8 0.0 4.3 6.4 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) FRG1 PF06229.7 AEO68042.1 - 0.15 11.4 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 FRG1-like family Gti1_Pac2 PF09729.4 AEO68043.1 - 3.3e-48 163.7 0.7 2.4e-46 157.6 0.5 2.2 1 1 0 1 1 1 1 Gti1/Pac2 family Linker_histone PF00538.14 AEO68044.1 - 4.5e-25 87.5 0.1 9.5e-25 86.4 0.0 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family FliE PF02049.13 AEO68044.1 - 0.29 11.1 0.1 0.29 11.1 0.1 2.9 3 1 0 3 3 3 0 Flagellar hook-basal body complex protein FliE ELYS PF13934.1 AEO68046.1 - 7.8e-62 208.9 0.0 9.7e-62 208.6 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly PolyA_pol_arg_C PF12626.2 AEO68046.1 - 0.081 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus CVNH PF08881.5 AEO68047.1 - 6.2e-06 26.3 0.3 1.5e-05 25.1 0.2 1.7 1 1 0 1 1 1 1 CVNH domain OMP_b-brl PF13505.1 AEO68047.1 - 0.24 11.3 0.7 0.43 10.5 0.5 1.7 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain RPAP1_C PF08620.5 AEO68048.1 - 3.2e-29 100.5 0.0 5.5e-29 99.8 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 AEO68048.1 - 1.4e-16 59.8 1.1 2.3e-16 59.0 0.7 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal HUN PF08729.5 AEO68049.1 - 8.7e-14 51.1 0.6 1.8e-13 50.1 0.4 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain MFS_1 PF07690.11 AEO68050.1 - 3e-32 111.7 47.8 2.8e-31 108.5 30.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MMPL PF03176.10 AEO68050.1 - 0.011 14.4 5.8 1 8.0 0.1 2.5 2 0 0 2 2 2 0 MMPL family Glyco_hydro_43 PF04616.9 AEO68051.1 - 1.4e-16 60.4 3.2 2.2e-16 59.7 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RasGAP PF00616.14 AEO68053.1 - 2.6e-55 187.1 0.6 1.3e-54 184.8 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 AEO68053.1 - 3.9e-29 101.1 4.7 3.9e-29 101.1 3.3 2.3 2 0 0 2 2 2 1 RasGAP C-terminus MeMO_Hyd_G PF02964.11 AEO68053.1 - 0.1 12.5 0.2 0.1 12.5 0.1 1.7 2 0 0 2 2 2 0 Methane monooxygenase, hydrolase gamma chain DUF972 PF06156.8 AEO68053.1 - 6.4 7.1 12.9 7.3 6.9 1.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF972) XFP_N PF09364.5 AEO68055.1 - 5.4e-178 591.3 0.0 6.9e-178 590.9 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 AEO68055.1 - 7.6e-83 276.4 0.0 1.3e-82 275.6 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 AEO68055.1 - 5.1e-81 270.9 0.0 6.9e-81 270.5 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 AEO68055.1 - 0.2 11.1 0.2 0.74 9.3 0.1 2.0 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PUF PF00806.14 AEO68056.1 - 9.7e-13 46.8 0.0 0.19 11.2 0.0 6.7 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Herpes_capsid PF06112.6 AEO68056.1 - 1 9.4 8.1 1.1 9.3 0.6 3.1 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein HAD_2 PF13419.1 AEO68057.1 - 2.7e-25 89.5 0.0 3.6e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO68057.1 - 0.00039 20.0 0.0 0.00074 19.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 AEO68057.1 - 0.0081 16.5 0.0 0.049 14.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HNH PF01844.18 AEO68058.1 - 0.00025 20.8 0.4 0.00047 19.9 0.3 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.1 AEO68058.1 - 0.02 14.6 0.3 0.041 13.6 0.2 1.5 1 0 0 1 1 1 0 HNH endonuclease Big_3_2 PF12245.3 AEO68060.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) AMMECR1 PF01871.12 AEO68061.1 - 4.2e-45 152.9 0.0 2.1e-44 150.6 0.0 1.8 2 0 0 2 2 2 1 AMMECR1 ATP-synt_B PF00430.13 AEO68061.1 - 0.089 12.5 0.3 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) SR-25 PF10500.4 AEO68061.1 - 0.46 9.9 8.0 0.67 9.3 5.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ras PF00071.17 AEO68062.1 - 3.9e-38 130.3 0.0 1.7e-24 86.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 AEO68062.1 - 1.6e-11 44.7 0.0 3.3e-11 43.7 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 AEO68062.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AEO68062.1 - 0.063 12.7 0.0 1.2 8.4 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PRK PF00485.13 AEO68062.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF2964 PF11177.3 AEO68063.1 - 0.0097 15.8 0.5 0.021 14.7 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2964) Pyridoxal_deC PF00282.14 AEO68065.1 - 1.4e-72 244.2 0.0 2.8e-64 216.8 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 AEO68065.1 - 8.3e-06 25.1 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 AEO68065.1 - 0.00069 18.4 0.0 0.001 17.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 AEO68065.1 - 0.004 15.6 0.0 0.0059 15.1 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Thi4 PF01946.12 AEO68066.1 - 9.4e-100 332.4 0.1 1.1e-99 332.1 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 AEO68066.1 - 2.4e-08 33.2 0.9 5.2e-07 28.9 0.6 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO68066.1 - 2.9e-05 24.0 0.5 7.3e-05 22.7 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 AEO68066.1 - 4e-05 22.6 0.4 0.00014 20.8 0.2 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 AEO68066.1 - 0.00037 20.4 0.1 0.00055 19.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO68066.1 - 0.0004 20.1 1.4 0.00088 19.0 0.1 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 AEO68066.1 - 0.0021 16.9 1.3 0.0097 14.7 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 AEO68066.1 - 0.0084 16.1 0.1 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO68066.1 - 0.0098 15.0 0.2 0.016 14.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 AEO68066.1 - 0.025 13.2 0.2 0.036 12.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 AEO68066.1 - 0.026 13.0 0.3 0.038 12.4 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 AEO68066.1 - 0.12 12.7 0.2 0.35 11.3 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4243 PF14027.1 AEO68068.1 - 5.1e-17 62.3 0.0 7.1e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF3262 PF11660.3 AEO68068.1 - 1.4 9.0 4.2 0.65 10.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) LCCL PF03815.14 AEO68069.1 - 3.7e-21 74.9 0.0 5.2e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 LCCL domain MAM33 PF02330.11 AEO68070.1 - 5.2e-31 108.0 1.2 1.6e-30 106.3 0.8 1.7 1 1 0 1 1 1 1 Mitochondrial glycoprotein DUF2962 PF11176.3 AEO68072.1 - 4.2e-42 143.3 4.3 4.8e-42 143.1 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) RRP7 PF12923.2 AEO68072.1 - 0.1 12.6 0.6 0.1 12.6 0.4 2.5 2 1 1 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) DUF2031 PF09592.5 AEO68072.1 - 0.28 10.3 1.9 3.4 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) BAR_2 PF10455.4 AEO68072.1 - 1.6 7.5 5.1 2.1 7.2 3.5 1.3 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking XPG_I PF00867.13 AEO68073.1 - 2.6e-25 88.3 0.0 5.5e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 AEO68073.1 - 3.9e-23 81.6 0.0 9.2e-23 80.4 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 AEO68073.1 - 0.0005 19.6 0.0 0.00098 18.6 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 AEO68073.1 - 0.033 14.4 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold SURF6 PF04935.7 AEO68074.1 - 2e-48 164.4 45.9 2e-48 164.4 31.8 4.0 2 1 0 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 AEO68074.1 - 1e-16 60.7 0.2 1e-16 60.7 0.2 7.2 5 2 1 6 6 6 1 60S ribosome biogenesis protein Rrp14 GPP34 PF05719.6 AEO68075.1 - 2.9e-65 220.2 0.1 3.4e-65 219.9 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Oxysterol_BP PF01237.13 AEO68076.1 - 3e-53 180.5 0.0 1e-41 142.6 0.0 2.5 2 1 0 2 2 2 2 Oxysterol-binding protein CP2 PF04516.10 AEO68077.1 - 1.3e-85 286.2 0.0 1.8e-85 285.7 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor CG-1 PF03859.11 AEO68077.1 - 0.0051 16.3 0.6 0.83 9.2 0.1 2.7 3 0 0 3 3 3 1 CG-1 domain Tektin PF03148.9 AEO68077.1 - 0.0051 15.4 0.1 0.0083 14.7 0.1 1.2 1 0 0 1 1 1 1 Tektin family DUF2681 PF10883.3 AEO68077.1 - 0.021 15.0 0.4 0.04 14.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Phage_G PF02306.10 AEO68077.1 - 0.028 14.0 0.1 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Major spike protein (G protein) CDI PF02234.14 AEO68077.1 - 0.035 13.9 0.2 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor TMF_DNA_bd PF12329.3 AEO68077.1 - 0.073 12.8 0.3 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding eIF2A PF08662.6 AEO68079.1 - 2.8e-77 258.8 0.0 2.6e-76 255.6 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 AEO68079.1 - 2.2e-06 27.3 1.7 0.24 11.3 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat CDV3 PF15359.1 AEO68079.1 - 0.011 15.8 0.3 0.011 15.8 0.2 2.7 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 DUF605 PF04652.11 AEO68079.1 - 0.62 9.4 11.0 0.88 8.9 7.6 1.1 1 0 0 1 1 1 0 Vta1 like PP28 PF10252.4 AEO68081.1 - 2.8e-26 91.3 11.3 2.8e-26 91.3 7.9 2.3 2 0 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 WBS28 PF15164.1 AEO68082.1 - 0.071 12.1 1.1 0.13 11.3 0.7 1.3 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue GTP_EFTU PF00009.22 AEO68083.1 - 2.2e-40 138.1 1.7 1.2e-39 135.6 1.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 AEO68083.1 - 8.7e-24 83.5 0.0 2.2e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 AEO68083.1 - 1.6e-15 56.9 2.1 1.6e-08 34.5 0.0 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF2_N PF04760.10 AEO68083.1 - 1.4e-09 37.4 0.0 2.4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 AEO68083.1 - 7.1e-08 32.4 0.1 1.5e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AEO68083.1 - 1.4e-06 28.7 0.1 2.7e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 AEO68083.1 - 9.2e-06 25.1 0.1 2e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 AEO68083.1 - 1.1e-05 24.8 0.0 1.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 AEO68083.1 - 0.00039 19.7 0.3 0.00083 18.6 0.2 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 AEO68083.1 - 0.0025 17.0 0.2 0.0059 15.8 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ArgK PF03308.11 AEO68083.1 - 0.036 12.8 1.6 0.081 11.6 0.9 1.7 1 1 0 1 1 1 0 ArgK protein GTP_EFTU_D4 PF14578.1 AEO68083.1 - 0.055 13.1 6.0 0.15 11.7 1.6 2.5 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.18 AEO68083.1 - 0.97 9.2 7.1 4.7 7.0 0.0 3.5 3 1 1 4 4 4 0 Dynamin family DUF367 PF04034.8 AEO68084.1 - 6e-46 155.1 0.0 8.1e-46 154.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 AEO68084.1 - 1.7e-11 43.4 0.6 3e-11 42.7 0.4 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI VHS PF00790.14 AEO68085.1 - 2.3e-43 147.2 0.0 9.4e-43 145.2 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 AEO68085.1 - 2.4e-24 85.2 0.3 5.5e-24 84.0 0.2 1.6 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 AEO68085.1 - 1.2e-19 70.7 0.1 1.2e-19 70.7 0.0 2.5 2 0 0 2 2 2 1 Adaptin C-terminal domain AAA_16 PF13191.1 AEO68086.1 - 1.8e-07 31.3 0.2 1e-06 28.8 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.9 AEO68086.1 - 0.00097 18.4 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 AEO68086.1 - 0.0032 17.0 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein FHA PF00498.21 AEO68088.1 - 2.5e-16 59.5 0.0 4.6e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain MIP-T3 PF10243.4 AEO68088.1 - 5.1 5.4 29.9 6.9 5.0 20.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 IBR PF01485.16 AEO68089.1 - 4.3e-23 80.9 44.8 9.4e-13 47.8 4.5 4.5 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 AEO68089.1 - 9.9e-06 25.4 7.4 9.9e-06 25.4 5.1 4.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO68089.1 - 3e-05 23.5 41.3 0.00018 21.0 3.3 4.6 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO68089.1 - 0.00048 19.8 44.5 0.00064 19.5 4.9 3.6 2 1 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 AEO68089.1 - 0.013 15.2 7.7 0.013 15.2 5.4 3.8 3 1 0 3 3 3 0 zinc-RING finger domain CoA_trans PF01144.18 AEO68090.1 - 9.6e-99 328.9 1.1 1.2e-58 197.8 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 AEO68090.1 - 0.0021 17.7 0.1 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Redoxin PF08534.5 AEO68091.1 - 7.3e-26 90.4 0.0 9.1e-26 90.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin DUF948 PF06103.6 AEO68092.1 - 1.1 9.1 4.3 3.4 7.6 0.1 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) GAGA_bind PF06217.7 AEO68092.1 - 2.2 8.1 6.8 0.64 9.9 2.5 1.6 2 0 0 2 2 2 0 GAGA binding protein-like family DUF167 PF02594.11 AEO68093.1 - 8.1e-17 60.9 0.2 9.8e-17 60.6 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 DASH_Dam1 PF08653.5 AEO68094.1 - 1.5e-27 95.0 1.0 2.2e-27 94.5 0.7 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.15 AEO68095.1 - 4.6e-43 146.4 0.0 8.1e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AEO68095.1 - 7.5e-15 54.7 1.9 5.8e-14 51.9 0.0 2.8 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AEO68095.1 - 8.8e-11 41.9 0.0 1.9e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HIT PF01230.18 AEO68096.1 - 6.7e-22 77.8 0.0 1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 AEO68096.1 - 4.4e-14 52.7 0.1 1.3e-13 51.2 0.0 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 AEO68096.1 - 4.3e-05 23.1 0.1 6.9e-05 22.4 0.1 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Mog1 PF04603.7 AEO68097.1 - 5.3e-19 68.5 0.0 8.5e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Ran-interacting Mog1 protein SprT-like PF10263.4 AEO68098.1 - 6.8e-48 162.2 1.9 9.1e-48 161.8 1.4 1.2 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.14 AEO68098.1 - 0.01 16.0 0.1 0.01 16.0 0.1 2.7 3 0 0 3 3 3 0 HMG (high mobility group) box Zn-ribbon_8 PF09723.5 AEO68098.1 - 0.019 14.9 0.4 0.048 13.6 0.1 1.8 2 0 0 2 2 2 0 Zinc ribbon domain Peptidase_MA_2 PF13485.1 AEO68098.1 - 0.024 14.6 0.1 0.11 12.5 0.0 2.0 1 1 1 2 2 2 0 Peptidase MA superfamily YABBY PF04690.8 AEO68098.1 - 0.06 13.5 0.1 0.06 13.5 0.1 2.2 2 1 0 2 2 2 0 YABBY protein Glucan_synthase PF02364.10 AEO68099.1 - 0 1458.0 0.0 0 1457.0 0.0 1.5 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 AEO68099.1 - 3.4e-40 136.6 0.6 8.4e-40 135.3 0.4 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.16 AEO68100.1 - 1.6e-40 139.2 0.0 1.9e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 AEO68100.1 - 0.017 13.3 0.0 0.025 12.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Xan_ur_permease PF00860.15 AEO68101.1 - 5.9e-65 219.2 31.1 1.2e-63 214.9 21.5 2.1 1 1 0 1 1 1 1 Permease family SET PF00856.23 AEO68102.1 - 5.8e-12 46.2 0.0 3.2e-10 40.5 0.0 2.8 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 AEO68102.1 - 1.4e-10 40.6 3.8 3.1e-05 23.5 0.8 2.6 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 AEO68102.1 - 5.5e-07 29.0 5.9 5.7e-05 22.7 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 AEO68102.1 - 0.0024 17.7 5.3 0.0027 17.6 1.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 AEO68102.1 - 0.0029 17.9 0.2 0.015 15.6 0.1 2.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 AEO68102.1 - 0.0031 17.0 6.9 0.015 14.8 0.1 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 AEO68102.1 - 0.037 14.7 0.1 0.037 14.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 AEO68102.1 - 0.062 13.1 2.3 0.13 12.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 AEO68102.1 - 0.14 12.0 1.3 1.1 9.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO68102.1 - 0.39 11.4 0.0 0.39 11.4 0.0 4.2 5 1 0 5 5 5 0 Tetratricopeptide repeat HemY_N PF07219.8 AEO68105.1 - 0.031 13.8 3.8 0.95 9.0 0.0 2.2 2 0 0 2 2 2 0 HemY protein N-terminus MARVEL PF01284.18 AEO68105.1 - 0.041 13.6 12.1 0.053 13.3 8.4 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF4282 PF14110.1 AEO68105.1 - 0.063 13.4 4.5 2.1 8.5 2.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) UNC-50 PF05216.8 AEO68105.1 - 0.13 11.3 4.0 0.1 11.7 1.6 1.6 2 0 0 2 2 2 0 UNC-50 family Myc_target_1 PF15179.1 AEO68105.1 - 0.15 11.6 8.1 0.03 13.9 1.7 2.0 2 0 0 2 2 2 0 Myc target protein 1 7TMR-DISM_7TM PF07695.6 AEO68105.1 - 0.23 11.1 14.5 2.9 7.5 6.8 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF1003 PF06210.6 AEO68105.1 - 0.23 11.3 1.1 0.96 9.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) DUF4131 PF13567.1 AEO68105.1 - 0.36 10.2 4.0 0.57 9.5 1.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CTP_transf_1 PF01148.15 AEO68105.1 - 0.61 9.7 9.2 1.4 8.4 6.5 1.6 1 1 0 1 1 1 0 Cytidylyltransferase family DUF4018 PF13210.1 AEO68105.1 - 1.1 8.6 6.1 0.11 11.9 1.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4018) DUF1469 PF07332.6 AEO68105.1 - 1.2 8.8 5.4 4.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Ubie_methyltran PF01209.13 AEO68106.1 - 8.8e-08 31.5 0.0 2.5e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AEO68106.1 - 5.7e-07 29.9 0.0 8.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO68106.1 - 1.6e-06 28.1 0.1 2.8e-06 27.3 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO68106.1 - 1.4e-05 25.4 0.0 2.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO68106.1 - 1.7e-05 24.4 0.0 2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO68106.1 - 7.2e-05 23.3 0.0 0.00011 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO68106.1 - 9.4e-05 22.7 0.0 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO68106.1 - 0.00046 19.9 0.0 0.0017 18.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 AEO68106.1 - 0.17 10.8 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DUF605 PF04652.11 AEO68107.1 - 8.8 5.6 14.0 10 5.3 9.7 1.2 1 0 0 1 1 1 0 Vta1 like H2TH PF06831.9 AEO68108.1 - 0.093 12.4 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain Mucin PF01456.12 AEO68108.1 - 0.38 10.5 24.1 1.2 8.9 16.7 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein MFS_1 PF07690.11 AEO68110.1 - 4.5e-31 107.8 28.9 4.5e-31 107.8 20.0 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily vMSA PF00695.14 AEO68110.1 - 0.45 9.6 3.8 0.12 11.5 0.2 1.7 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus CoA_trans PF01144.18 AEO68111.1 - 1.2e-90 302.4 0.2 2.3e-58 196.9 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 AEO68111.1 - 0.00067 19.3 0.3 0.0014 18.3 0.2 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mito_carr PF00153.22 AEO68113.1 - 4.7e-09 35.8 0.3 3.6e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Zn_clus PF00172.13 AEO68114.1 - 2.4e-05 24.1 8.5 4.2e-05 23.3 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO68114.1 - 0.00086 18.2 0.3 0.003 16.4 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain MutS_V PF00488.16 AEO68115.1 - 2.3e-80 269.3 0.0 4.3e-80 268.4 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AEO68115.1 - 8.1e-50 169.4 0.1 1.5e-49 168.6 0.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 AEO68115.1 - 4e-32 110.5 0.1 1.1e-31 109.1 0.0 1.8 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 AEO68115.1 - 2.7e-15 56.6 0.0 1e-14 54.7 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 AEO68115.1 - 5.2e-14 52.1 0.5 1.1e-13 51.1 0.4 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 AEO68115.1 - 0.0029 17.9 0.1 0.0029 17.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AEO68115.1 - 0.012 15.1 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 AEO68115.1 - 0.041 13.8 1.4 0.082 12.8 0.2 2.0 2 0 0 2 2 2 0 AAA domain FAD_binding_3 PF01494.14 AEO68116.1 - 8.6e-23 80.9 0.2 3.6e-22 78.9 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 AEO68116.1 - 2.1e-07 30.2 0.0 1e-06 27.9 0.0 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 AEO68116.1 - 1.4e-06 27.5 0.0 6e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO68116.1 - 1.2e-05 25.2 0.1 4.4e-05 23.4 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AEO68116.1 - 3.1e-05 24.1 0.1 8.3e-05 22.7 0.0 1.8 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO68116.1 - 0.00015 21.5 0.1 0.0044 16.8 0.1 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.9 AEO68116.1 - 0.00019 20.0 0.3 0.00038 19.0 0.2 1.4 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 AEO68116.1 - 0.00037 20.4 0.2 0.00061 19.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO68116.1 - 0.00045 19.1 0.2 0.00084 18.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 AEO68116.1 - 0.00063 18.9 1.0 0.0011 18.1 0.5 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 AEO68116.1 - 0.00099 18.0 0.1 0.0013 17.6 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 AEO68116.1 - 0.0013 19.0 0.1 0.011 16.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO68116.1 - 0.0025 16.9 0.0 0.0046 16.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 AEO68116.1 - 0.017 14.2 0.0 4.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 AEO68116.1 - 0.027 14.1 0.3 0.043 13.4 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 AEO68116.1 - 0.068 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ImcF-related_N PF14331.1 AEO68116.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain Med3 PF11593.3 AEO68117.1 - 4.9 6.2 6.0 4.9 6.2 4.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MFS_1 PF07690.11 AEO68118.1 - 3.1e-31 108.3 55.7 1.6e-20 73.1 23.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO68118.1 - 5.3e-11 41.7 37.3 4.9e-08 31.9 8.0 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 AEO68118.1 - 5.4e-06 25.0 24.2 1.2e-05 23.8 13.8 2.2 1 1 0 1 1 1 1 MFS/sugar transport protein Diphthamide_syn PF01866.12 AEO68119.1 - 2.6e-51 174.6 0.0 3.7e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein COesterase PF00135.23 AEO68120.1 - 4.6e-92 309.4 0.1 6.3e-92 308.9 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO68120.1 - 3e-08 33.5 0.1 1.1e-07 31.6 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold HET PF06985.6 AEO68123.1 - 1.8e-19 70.2 0.0 2.1e-18 66.8 0.0 2.6 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 AEO68123.1 - 3.6e-19 68.9 0.0 6.4e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 AEO68123.1 - 0.0032 17.2 0.1 0.6 9.8 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 AEO68124.1 - 2.8e-21 75.8 0.0 5.3e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO68124.1 - 9.7e-11 41.2 0.0 1.7e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Mucin PF01456.12 AEO68125.1 - 0.4 10.4 13.4 0.5 10.1 9.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Fasciclin PF02469.17 AEO68126.1 - 5e-38 129.9 0.1 4e-23 81.8 0.0 2.9 2 1 0 2 2 2 2 Fasciclin domain SR-25 PF10500.4 AEO68126.1 - 0.23 10.8 12.6 0.34 10.3 8.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pro_CA PF00484.14 AEO68127.1 - 2.4e-48 163.9 0.1 3.1e-48 163.6 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Pkinase PF00069.20 AEO68128.1 - 2.4e-05 23.6 0.0 5e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 AEO68128.1 - 0.00016 21.5 0.0 0.00042 20.1 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 AEO68128.1 - 0.057 12.4 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF2713 PF10897.3 AEO68128.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) Cupin_2 PF07883.6 AEO68129.1 - 0.04 13.4 0.0 0.071 12.6 0.0 1.5 1 1 0 1 1 1 0 Cupin domain NMT1 PF09084.6 AEO68131.1 - 1.5e-75 253.5 0.0 1.9e-75 253.1 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 AEO68131.1 - 2e-08 33.9 0.3 0.016 14.6 0.0 3.6 2 1 2 4 4 4 2 NMT1-like family PBP_like PF12727.2 AEO68131.1 - 0.067 12.1 0.0 0.75 8.7 0.0 2.1 2 0 0 2 2 2 0 PBP superfamily domain Tannase PF07519.6 AEO68132.1 - 2.7e-100 336.3 0.1 3.4e-100 336.0 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 AEO68132.1 - 0.029 14.1 0.1 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Collagen PF01391.13 AEO68133.1 - 0.00022 20.7 0.0 0.0026 17.2 0.0 2.1 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Rab5ip PF07019.7 AEO68133.1 - 1.3 9.2 20.4 66 3.7 0.0 3.2 2 1 0 2 2 2 0 Rab5-interacting protein (Rab5ip) zf-U1 PF06220.7 AEO68134.1 - 2.1 8.0 3.8 0.99 9.0 1.0 1.7 1 1 0 1 1 1 0 U1 zinc finger GFA PF04828.9 AEO68135.1 - 3.3e-11 42.9 0.4 3.2e-08 33.4 0.0 3.1 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 AEO68135.1 - 0.035 13.3 0.1 0.035 13.3 0.0 4.2 5 1 0 5 5 5 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AEO68135.1 - 0.069 12.6 0.2 0.069 12.6 0.1 4.1 7 0 0 7 7 7 0 zinc-ribbon domain Plant_zn_clust PF10533.4 AEO68135.1 - 0.68 9.6 5.0 1.8 8.2 0.2 2.7 2 0 0 2 2 2 0 Plant zinc cluster domain UPF0547 PF10571.4 AEO68135.1 - 0.98 9.1 0.0 0.98 9.1 0.0 3.6 6 0 0 6 6 6 0 Uncharacterised protein family UPF0547 DZR PF12773.2 AEO68135.1 - 1.7 8.5 0.0 1.7 8.5 0.0 3.9 5 0 0 5 5 5 0 Double zinc ribbon RNA_POL_M_15KD PF02150.11 AEO68135.1 - 9.9 5.9 8.2 4.9 6.9 0.1 3.2 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit zf-C2H2_4 PF13894.1 AEO68137.1 - 1.1e-12 47.3 33.8 0.027 14.7 1.8 7.3 7 0 0 7 7 7 5 C2H2-type zinc finger zf-met PF12874.2 AEO68137.1 - 5e-11 42.3 34.2 9.2e-06 25.6 1.1 6.8 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 AEO68137.1 - 7.5e-11 42.0 31.8 0.01 15.9 0.6 6.8 2 2 5 7 7 7 4 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 AEO68137.1 - 8.2e-11 41.7 34.5 8.6e-05 22.5 0.2 6.9 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 AEO68137.1 - 9.2e-10 38.2 41.9 0.0066 16.7 1.8 7.3 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 AEO68137.1 - 1.2e-06 28.2 22.0 0.022 14.6 0.5 6.1 6 0 0 6 6 6 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO68137.1 - 8.3e-06 25.8 35.7 0.57 10.5 0.3 7.1 7 0 0 7 7 7 5 Zinc-finger double domain zf-Di19 PF05605.7 AEO68137.1 - 0.098 12.8 0.2 0.098 12.8 0.2 4.7 4 2 2 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding AKAP95 PF04988.7 AEO68137.1 - 0.17 11.6 15.2 0.17 11.6 0.9 3.3 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Calcipressin PF04847.7 AEO68138.1 - 2.1 7.9 6.5 0.45 10.0 0.2 2.2 2 0 0 2 2 2 0 Calcipressin FAD_binding_3 PF01494.14 AEO68139.1 - 1.9e-19 69.9 0.0 4.7e-19 68.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 AEO68139.1 - 1e-05 25.8 0.0 0.00027 21.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO68139.1 - 0.00044 20.2 0.1 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO68139.1 - 0.002 17.1 0.0 0.0062 15.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AEO68139.1 - 0.0032 15.9 0.0 0.0049 15.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.5 AEO68139.1 - 0.0038 16.1 0.0 0.0078 15.0 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.9 AEO68139.1 - 0.0088 15.9 0.0 0.018 14.9 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AEO68139.1 - 0.027 13.3 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 AEO68139.1 - 0.04 13.0 0.1 0.2 10.6 0.1 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Peptidase_M24 PF00557.19 AEO68140.1 - 2.5e-46 157.8 0.2 3.1e-46 157.5 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 AEO68140.1 - 4.2e-05 23.3 5.9 0.00011 22.0 4.1 1.7 1 0 0 1 1 1 1 MYND finger Cornichon PF03311.9 AEO68141.1 - 1.8e-54 183.2 8.9 2.1e-54 183.1 6.2 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.27 AEO68142.1 - 2.8e-34 115.7 3.2 1.5e-09 37.3 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ADH_N PF08240.7 AEO68143.1 - 2.5e-05 24.0 0.1 9.9e-05 22.0 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO68143.1 - 0.13 11.8 2.2 0.29 10.6 1.5 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase OsmC PF02566.14 AEO68143.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 OsmC-like protein Macoilin PF09726.4 AEO68144.1 - 0.015 13.6 10.6 0.018 13.3 7.3 1.2 1 0 0 1 1 1 0 Transmembrane protein PAP1 PF08601.5 AEO68144.1 - 0.11 12.1 17.3 0.19 11.3 12.0 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 MFS_1 PF07690.11 AEO68145.1 - 5.1e-24 84.6 24.9 1.7e-23 82.9 17.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO68145.1 - 1.5e-08 33.6 9.8 1.5e-08 33.6 6.8 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 AEO68145.1 - 3.1e-05 22.3 1.2 4.1e-05 21.9 0.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 AEO68145.1 - 0.037 12.4 17.7 0.012 14.0 2.7 3.0 2 1 1 3 3 3 0 MFS/sugar transport protein FA_desaturase PF00487.19 AEO68145.1 - 0.69 9.2 6.4 3 7.2 1.4 2.3 2 0 0 2 2 2 0 Fatty acid desaturase Pam17 PF08566.5 AEO68145.1 - 8.4 6.0 6.0 22 4.6 0.2 2.8 2 1 0 3 3 3 0 Mitochondrial import protein Pam17 DUF1748 PF08520.5 AEO68146.1 - 9.3e-36 121.3 0.2 1.1e-35 121.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.16 AEO68147.1 - 6.2e-170 564.3 5.2 8.3e-170 563.9 3.6 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 AEO68147.1 - 3.6e-31 107.1 0.0 1e-30 105.6 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 AEO68147.1 - 6.2e-05 21.9 1.3 0.00017 20.5 0.7 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 AEO68147.1 - 0.016 14.1 0.3 0.16 10.8 0.0 2.2 2 1 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DUF3439 PF11921.3 AEO68148.1 - 0.17 11.6 7.3 0.27 10.9 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) HET PF06985.6 AEO68149.1 - 3.9e-18 65.9 0.0 8.4e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Subtilosin_A PF11420.3 AEO68149.1 - 2.4 8.2 4.4 29 4.8 0.0 3.1 3 0 0 3 3 3 0 Bacteriocin subtilosin A Fungal_trans PF04082.13 AEO68150.1 - 3.4e-18 65.4 0.0 5.8e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO68150.1 - 3.4e-05 23.6 8.8 6.3e-05 22.7 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 AEO68153.1 - 8.5e-44 149.6 0.0 4.2e-43 147.3 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO68153.1 - 7e-31 107.2 0.0 1e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO68153.1 - 0.0036 16.4 0.0 0.097 11.7 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 AEO68153.1 - 0.24 10.1 0.0 0.4 9.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RAP-1 PF03085.10 AEO68154.1 - 1.8 7.8 3.9 1.8 7.8 2.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Glyco_hydro_61 PF03443.9 AEO68157.1 - 3.2e-53 180.7 0.6 3.7e-53 180.5 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Spt5-NGN PF03439.8 AEO68159.1 - 5.3e-25 86.9 0.0 8.9e-25 86.2 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.2 AEO68159.1 - 1.4e-22 80.4 46.5 2e-20 73.4 24.2 4.7 2 1 2 4 4 4 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.3 AEO68159.1 - 3.2e-18 66.1 10.7 3.2e-18 66.1 7.4 4.5 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 AEO68159.1 - 0.00023 20.7 22.7 0.037 13.7 1.9 5.8 6 1 0 6 6 6 2 KOW motif IER PF05760.7 AEO68159.1 - 0.16 11.8 5.5 0.39 10.6 3.8 1.6 1 0 0 1 1 1 0 Immediate early response protein (IER) Glyco_hydro_28 PF00295.12 AEO68160.1 - 7.7e-56 189.4 5.4 1.2e-55 188.8 3.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Abhydrolase_6 PF12697.2 AEO68162.1 - 5.8e-14 52.5 4.1 8.5e-14 51.9 2.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO68162.1 - 7.5e-12 45.2 0.6 1.1e-11 44.6 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO68162.1 - 0.00013 21.5 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 AEO68162.1 - 0.019 14.5 2.0 0.025 14.1 0.7 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 AEO68162.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase NMT_C PF02799.10 AEO68164.1 - 2.4e-78 261.9 0.0 3.4e-78 261.4 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 AEO68164.1 - 6.3e-67 224.2 0.0 9.7e-67 223.6 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 AEO68164.1 - 6.1e-06 26.1 0.0 1.9e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO68164.1 - 0.017 15.2 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain INO80_Ies4 PF08193.6 AEO68164.1 - 0.085 12.7 7.7 0.15 11.9 5.3 1.3 1 0 0 1 1 1 0 INO80 complex subunit Ies4 Abhydrolase_6 PF12697.2 AEO68165.1 - 2.4e-21 76.6 2.4 6e-21 75.3 1.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO68165.1 - 1.1e-11 44.6 0.0 4.8e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO68165.1 - 3.3e-08 33.3 0.1 0.0003 20.4 0.0 3.0 2 1 0 2 2 2 2 alpha/beta hydrolase fold DUF2048 PF09752.4 AEO68165.1 - 0.0089 14.9 0.2 0.015 14.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) UPF0227 PF05728.7 AEO68165.1 - 0.0095 15.6 0.0 3.3 7.3 0.0 2.5 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0227) Abhydrolase_4 PF08386.5 AEO68165.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Hydrolase_4 PF12146.3 AEO68165.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 AEO68165.1 - 0.14 11.5 0.0 5.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Tannase PF07519.6 AEO68166.1 - 4e-68 230.2 0.3 4.9e-34 117.8 0.3 2.0 2 0 0 2 2 2 2 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 AEO68166.1 - 6.8e-05 22.8 5.5 0.00018 21.4 3.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO68166.1 - 0.0022 17.2 0.1 1.6 7.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO68166.1 - 0.013 15.2 0.8 0.23 11.2 0.6 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO68166.1 - 0.03 13.8 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_114 PF03537.8 AEO68168.1 - 8.1e-09 35.1 0.1 1.6e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Polysacc_synt_4 PF04669.8 AEO68170.1 - 5.3e-27 94.4 1.0 2.6e-26 92.1 0.7 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Elongin_A PF06881.6 AEO68170.1 - 0.0044 17.3 1.6 0.0044 17.3 1.1 1.8 2 1 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Peroxin-22 PF12827.2 AEO68170.1 - 0.057 13.1 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Peroxisomal biogenesis protein family RNA_ligase PF09414.5 AEO68170.1 - 0.064 13.0 0.0 5.9 6.6 0.0 2.2 1 1 0 2 2 2 0 RNA ligase DUF2491 PF10679.4 AEO68170.1 - 0.07 12.1 0.7 0.079 11.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) ABC_tran PF00005.22 AEO68171.1 - 5.2e-57 191.9 0.0 4.7e-28 98.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AEO68171.1 - 2.3e-53 181.4 29.6 2.3e-28 99.4 8.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 AEO68171.1 - 1e-13 51.9 0.0 0.021 14.8 0.0 4.3 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 AEO68171.1 - 1e-11 44.4 0.2 5.1e-05 22.6 0.0 5.0 5 0 0 5 5 5 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AEO68171.1 - 3.7e-08 33.5 2.3 0.0027 17.6 0.4 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 AEO68171.1 - 2.3e-07 30.2 0.5 0.0099 15.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 AEO68171.1 - 2.3e-07 31.0 0.1 0.11 12.6 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 AEO68171.1 - 3.1e-07 31.2 0.1 0.045 14.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 AEO68171.1 - 8.9e-07 28.6 0.0 0.051 12.9 0.2 3.5 2 1 1 3 3 3 1 AAA-like domain DUF258 PF03193.11 AEO68171.1 - 1.4e-06 27.5 0.0 0.039 13.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 AEO68171.1 - 4.6e-06 26.1 1.5 0.17 11.2 0.0 4.1 4 0 0 4 4 4 2 AAA domain ABC_ATPase PF09818.4 AEO68171.1 - 4.7e-05 22.1 0.1 0.0011 17.5 0.1 2.8 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_18 PF13238.1 AEO68171.1 - 0.0001 22.6 0.5 0.5 10.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 AEO68171.1 - 0.0003 20.7 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 AEO68171.1 - 0.00059 19.7 0.1 0.23 11.3 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 AEO68171.1 - 0.00082 19.2 0.5 1.8 8.4 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_23 PF13476.1 AEO68171.1 - 0.002 18.4 0.6 2.4 8.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 AEO68171.1 - 0.0051 16.3 0.1 6.6 6.1 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_5 PF07728.9 AEO68171.1 - 0.0098 15.6 0.0 1.7 8.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) DUF87 PF01935.12 AEO68171.1 - 0.01 15.6 0.7 0.95 9.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 AEO68171.1 - 0.016 15.3 0.0 4.1 7.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 AEO68171.1 - 0.025 14.2 0.1 4 7.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MTH865 PF07747.6 AEO68171.1 - 0.043 13.4 0.2 1.3 8.6 0.0 2.8 3 0 0 3 3 2 0 MTH865-like family Mg_chelatase PF01078.16 AEO68171.1 - 0.044 12.9 0.0 0.71 8.9 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF3987 PF13148.1 AEO68171.1 - 0.045 12.3 0.0 3.6 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_14 PF13173.1 AEO68171.1 - 0.078 12.8 0.0 3.4 7.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain Miro PF08477.8 AEO68171.1 - 0.08 13.4 0.2 24 5.4 0.0 2.7 3 0 0 3 3 2 0 Miro-like protein APS_kinase PF01583.15 AEO68171.1 - 0.11 12.1 0.1 11 5.6 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase KaiC PF06745.8 AEO68171.1 - 0.15 11.1 0.8 39 3.2 0.1 3.5 4 0 0 4 4 4 0 KaiC NB-ARC PF00931.17 AEO68171.1 - 0.16 10.7 0.1 7.6 5.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_13 PF13166.1 AEO68171.1 - 0.73 8.2 0.0 9.5 4.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain DUF463 PF04317.7 AEO68173.1 - 0.01 14.4 0.0 0.013 14.0 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 AXE1 PF05448.7 AEO68173.1 - 0.2 10.1 0.1 0.33 9.3 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) MFS_1 PF07690.11 AEO68174.1 - 5.1e-27 94.5 38.3 1.6e-25 89.5 15.5 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 AEO68174.1 - 6.4e-06 24.6 3.6 1.2e-05 23.7 2.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1769 PF08588.5 AEO68175.1 - 1.5e-28 98.4 1.0 3.3e-28 97.3 0.3 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1769) PC_rep PF01851.17 AEO68176.1 - 2.5e-38 128.1 24.8 8.9e-09 35.1 0.0 10.3 11 0 0 11 11 11 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 AEO68176.1 - 5.7e-19 68.1 2.5 2.9e-12 46.7 0.0 6.1 4 1 2 7 7 7 3 HEAT repeats HEAT PF02985.17 AEO68176.1 - 2.7e-08 33.2 2.7 0.75 10.0 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 AEO68176.1 - 5e-07 30.0 5.0 0.0001 22.6 0.0 5.1 5 1 0 5 5 5 1 HEAT-like repeat mRNA_triPase PF02940.10 AEO68177.1 - 2.3e-58 197.4 0.0 3e-58 197.1 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Peptidase_M75 PF09375.5 AEO68178.1 - 0.0072 15.6 0.8 0.065 12.5 0.0 2.1 2 0 0 2 2 2 1 Imelysin FAD_binding_3 PF01494.14 AEO68179.1 - 2.2e-18 66.4 0.4 3e-12 46.2 0.3 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 AEO68179.1 - 0.0011 18.9 0.1 0.0079 16.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 AEO68179.1 - 0.23 10.2 0.0 0.79 8.5 0.0 1.9 2 1 0 2 2 2 0 Squalene epoxidase p450 PF00067.17 AEO68180.1 - 6.7e-48 163.3 0.0 8.5e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 AEO68181.1 - 0.00095 18.3 0.0 0.0029 16.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO68181.1 - 0.0088 15.1 0.0 0.053 12.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 AEO68182.1 - 0.076 12.1 0.0 0.091 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.12 AEO68182.1 - 0.077 12.0 0.0 0.094 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 AEO68183.1 - 6.5e-29 100.8 0.0 7.1e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO68183.1 - 2e-17 63.1 0.0 2.2e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 AEO68183.1 - 0.011 14.5 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 AEO68183.1 - 0.012 14.7 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO68183.1 - 0.016 14.9 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 AEO68183.1 - 0.043 12.7 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like WD40 PF00400.27 AEO68184.1 - 1.1e-73 240.6 21.6 1.1e-14 53.5 0.4 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 AEO68184.1 - 9.2e-12 43.8 13.5 0.0025 16.0 0.3 4.8 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AEO68184.1 - 0.00023 20.0 0.9 3.7 6.2 0.0 4.1 2 1 3 5 5 5 3 Nup133 N terminal like PD40 PF07676.7 AEO68184.1 - 0.034 13.8 0.5 6.9 6.4 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat APH PF01636.18 AEO68185.1 - 5.2e-19 68.9 2.6 5.2e-19 68.9 1.8 2.3 2 1 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO68185.1 - 0.0089 15.6 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 AEO68185.1 - 0.021 14.2 0.1 2.4 7.4 0.0 2.8 3 0 0 3 3 3 0 RIO1 family NmrA PF05368.8 AEO68186.1 - 8.5e-25 87.3 0.1 1e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO68186.1 - 6.2e-15 55.6 0.8 1.7e-14 54.2 0.2 1.9 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 AEO68186.1 - 8e-07 28.7 0.1 1.3e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 AEO68186.1 - 0.0085 16.0 2.5 0.014 15.3 0.2 2.1 2 0 0 2 2 2 1 short chain dehydrogenase F420_oxidored PF03807.12 AEO68186.1 - 0.012 15.9 0.1 0.037 14.4 0.1 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 AEO68186.1 - 0.014 14.4 0.1 0.019 13.9 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 AEO68186.1 - 0.072 12.9 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.14 AEO68186.1 - 0.074 11.7 0.0 0.3 9.7 0.0 1.9 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DFP PF04127.10 AEO68186.1 - 0.08 12.5 0.1 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Amidohydro_4 PF13147.1 AEO68186.1 - 0.51 10.3 5.2 0.39 10.7 0.1 2.1 1 1 0 2 2 2 0 Amidohydrolase zf-C2H2 PF00096.21 AEO68187.1 - 2.1e-06 27.6 3.4 0.0071 16.6 0.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO68187.1 - 0.0001 22.3 2.0 0.015 15.5 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO68187.1 - 0.0079 16.3 2.1 2.9 8.1 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 AEO68187.1 - 0.055 13.5 1.4 5.6 7.1 0.8 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.17 AEO68187.1 - 0.059 13.4 0.7 0.13 12.3 0.5 1.5 1 1 0 1 1 1 0 LIM domain zf-C2H2_6 PF13912.1 AEO68187.1 - 0.61 10.0 3.1 4.3 7.3 0.0 2.3 1 1 1 2 2 2 0 C2H2-type zinc finger DUF605 PF04652.11 AEO68187.1 - 0.77 9.0 10.7 0.9 8.8 7.4 1.2 1 0 0 1 1 1 0 Vta1 like DUF1804 PF08822.6 AEO68188.1 - 0.021 14.5 0.2 0.042 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Kinesin PF00225.18 AEO68189.1 - 2.7e-114 381.3 0.1 4.6e-114 380.5 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain AAA PF00004.24 AEO68189.1 - 0.019 15.1 0.5 0.6 10.3 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TMF_TATA_bd PF12325.3 AEO68189.1 - 0.15 11.8 6.5 0.24 11.1 2.4 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Sugar_tr PF00083.19 AEO68190.1 - 6.9e-117 390.7 26.6 1.1e-116 390.1 18.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO68190.1 - 6.2e-25 87.6 44.9 5.2e-19 68.1 9.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO68190.1 - 0.0001 20.8 39.8 0.00077 17.9 8.5 3.4 2 2 1 3 3 3 2 MFS/sugar transport protein Lysis_S PF04971.7 AEO68190.1 - 0.0078 15.8 0.6 0.032 13.9 0.4 2.1 1 0 0 1 1 1 1 Lysis protein S Myb_DNA-bind_6 PF13921.1 AEO68191.1 - 7.3e-07 29.1 0.8 9.8e-06 25.5 0.1 2.3 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO68191.1 - 0.0016 18.4 0.1 0.0038 17.2 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain UbiA PF01040.13 AEO68192.1 - 5.1e-31 107.8 25.9 7.7e-31 107.2 18.0 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Transaldolase PF00923.14 AEO68193.1 - 1.9e-48 165.0 0.1 2.1e-48 164.9 0.1 1.1 1 0 0 1 1 1 1 Transaldolase Mo-co_dimer PF03404.11 AEO68195.1 - 1.2e-24 86.4 0.1 1.9e-14 53.4 0.0 3.2 3 0 0 3 3 3 2 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 AEO68195.1 - 1.6e-14 53.4 0.0 2.6e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3506 PF12014.3 AEO68196.1 - 4.9e-46 155.9 0.0 1.7e-44 150.9 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 AEO68196.1 - 6.9e-07 28.8 0.5 1.8e-06 27.5 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO68196.1 - 0.00051 19.6 0.1 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 AEO68196.1 - 0.03 14.6 0.0 0.063 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A SDA1 PF05285.7 AEO68196.1 - 5.7 6.1 13.0 8.2 5.6 9.0 1.1 1 0 0 1 1 1 0 SDA1 Fungal_trans PF04082.13 AEO68197.1 - 2e-13 49.8 1.3 3.3e-13 49.1 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO68197.1 - 6.5e-09 35.5 9.3 1.3e-08 34.5 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phosphoprotein PF00922.12 AEO68197.1 - 1.5 7.9 3.1 1.7 7.8 0.9 1.9 2 0 0 2 2 2 0 Vesiculovirus phosphoprotein Cupin_2 PF07883.6 AEO68198.1 - 6.5e-05 22.3 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 AEO68198.1 - 0.027 14.1 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_3 PF05899.7 AEO68198.1 - 0.088 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_2 PF07883.6 AEO68199.1 - 1.2e-07 31.1 0.3 2.1e-07 30.3 0.2 1.5 1 1 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 AEO68199.1 - 0.016 14.9 0.1 0.023 14.3 0.1 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_3 PF05899.7 AEO68199.1 - 0.04 13.3 0.0 0.07 12.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF861) AIP3 PF03915.8 AEO68200.1 - 0.0042 16.0 16.1 0.084 11.7 0.1 2.4 2 0 0 2 2 2 2 Actin interacting protein 3 Fmp27_WPPW PF10359.4 AEO68200.1 - 0.011 14.2 12.1 1 7.7 0.0 2.4 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Spc7 PF08317.6 AEO68200.1 - 0.012 14.3 0.1 0.012 14.3 0.0 2.7 3 0 0 3 3 3 0 Spc7 kinetochore protein Sugarporin_N PF11471.3 AEO68200.1 - 0.015 14.8 0.4 0.015 14.8 0.3 2.9 2 0 0 2 2 1 0 Maltoporin periplasmic N-terminal extension TMF_TATA_bd PF12325.3 AEO68200.1 - 0.047 13.4 0.2 0.047 13.4 0.1 3.5 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 AEO68200.1 - 0.063 13.6 14.9 1.3 9.4 0.3 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 AEO68200.1 - 0.3 10.9 19.0 3 7.7 9.2 3.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 AEO68200.1 - 0.42 9.7 8.1 12 4.9 0.9 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Bap31 PF05529.7 AEO68200.1 - 0.51 9.7 14.4 0.64 9.4 0.3 3.1 3 0 0 3 3 3 0 B-cell receptor-associated protein 31-like Folliculin PF11704.3 AEO68200.1 - 0.74 9.3 10.7 1.6 8.3 2.3 2.9 3 0 0 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport IncA PF04156.9 AEO68200.1 - 2.8 7.4 31.7 1.1 8.8 1.3 3.2 1 1 1 2 2 2 0 IncA protein Prefoldin_2 PF01920.15 AEO68200.1 - 2.9 7.7 0.0 2.9 7.7 0.0 4.2 4 1 0 4 4 2 0 Prefoldin subunit SpoVR PF04293.8 AEO68200.1 - 4.1 5.6 9.9 2.5 6.3 5.2 1.8 2 0 0 2 2 2 0 SpoVR like protein FlxA PF14282.1 AEO68200.1 - 6.5 6.7 47.9 13 5.7 0.0 3.9 3 0 0 3 3 3 0 FlxA-like protein V_ATPase_I PF01496.14 AEO68200.1 - 6.7 4.4 12.3 15 3.2 0.0 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 AEO68200.1 - 7.3 6.3 17.9 39 3.9 0.4 3.6 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 F-box-like_2 PF13013.1 AEO68201.1 - 0.042 13.5 3.0 0.86 9.3 0.0 2.9 3 0 0 3 3 3 0 F-box-like domain DUF1423 PF07227.6 AEO68201.1 - 2.7 6.5 4.8 3.9 6.0 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) TMF_DNA_bd PF12329.3 AEO68202.1 - 0.00012 21.7 31.2 0.00014 21.6 0.3 6.7 5 2 2 7 7 6 1 TATA element modulatory factor 1 DNA binding Spc42p PF11544.3 AEO68202.1 - 0.0045 16.8 6.7 4.1 7.4 0.0 5.0 5 0 0 5 5 5 1 Spindle pole body component Spc42p FlaC_arch PF05377.6 AEO68202.1 - 0.017 15.0 2.7 3.6 7.5 0.0 4.2 5 0 0 5 5 4 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.3 AEO68202.1 - 0.019 14.7 26.9 0.32 10.7 0.9 5.2 3 1 2 5 5 5 0 TATA element modulatory factor 1 TATA binding TBPIP PF07106.8 AEO68202.1 - 0.024 14.1 11.2 4.2 6.8 0.9 4.4 3 1 0 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2031 PF09592.5 AEO68202.1 - 0.026 13.6 0.3 0.21 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) GAS PF13851.1 AEO68202.1 - 0.027 13.6 20.9 1.6 7.8 1.0 4.5 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 AEO68202.1 - 0.042 13.9 5.1 12 6.0 0.0 4.7 3 2 1 5 5 5 0 Fibrinogen alpha/beta chain family ERM PF00769.14 AEO68202.1 - 0.055 13.0 40.5 0.081 12.4 8.3 4.1 3 1 1 4 4 4 0 Ezrin/radixin/moesin family Geminin PF07412.7 AEO68202.1 - 0.057 13.1 8.0 0.056 13.1 1.5 2.5 2 0 0 2 2 2 0 Geminin DUF972 PF06156.8 AEO68202.1 - 0.077 13.3 12.7 0.8 10.0 0.1 5.0 3 1 1 4 4 4 0 Protein of unknown function (DUF972) ATG16 PF08614.6 AEO68202.1 - 0.09 12.5 30.6 0.11 12.3 2.0 4.6 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) SlyX PF04102.7 AEO68202.1 - 0.15 12.4 29.0 0.26 11.6 1.6 6.6 3 1 2 6 6 6 0 SlyX AAA_13 PF13166.1 AEO68202.1 - 0.26 9.6 10.7 0.77 8.1 0.0 3.0 2 1 1 3 3 3 0 AAA domain Reo_sigmaC PF04582.7 AEO68202.1 - 1.2 8.2 15.0 0.48 9.5 1.4 4.1 3 2 1 4 4 4 0 Reovirus sigma C capsid protein Spc7 PF08317.6 AEO68202.1 - 1.2 7.6 20.8 0.13 10.8 1.9 4.0 3 1 1 4 4 4 0 Spc7 kinetochore protein Mnd1 PF03962.10 AEO68202.1 - 1.7 8.2 25.0 0.27 10.8 1.0 4.5 3 1 1 4 4 4 0 Mnd1 family Baculo_PEP_C PF04513.7 AEO68202.1 - 1.9 8.3 12.9 8.1 6.2 0.7 4.3 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bap31 PF05529.7 AEO68202.1 - 2.2 7.6 9.5 1.5 8.2 0.4 3.3 2 1 1 3 3 3 0 B-cell receptor-associated protein 31-like DUF342 PF03961.8 AEO68202.1 - 3.2 6.0 9.6 7.6 4.8 0.3 3.6 3 1 2 5 5 5 0 Protein of unknown function (DUF342) DUF904 PF06005.7 AEO68202.1 - 4.3 7.7 23.8 0.42 10.9 0.3 5.9 4 2 1 5 5 5 0 Protein of unknown function (DUF904) Phage_GP20 PF06810.6 AEO68202.1 - 6.9 6.0 15.7 0.15 11.4 1.4 3.5 3 1 1 4 4 4 0 Phage minor structural protein GP20 DUF3584 PF12128.3 AEO68202.1 - 7.9 3.6 33.9 0.76 7.0 13.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) V-SNARE PF05008.10 AEO68202.1 - 8.2 6.6 23.3 0.1 12.7 0.7 6.2 5 2 2 7 7 7 0 Vesicle transport v-SNARE protein N-terminus Filament PF00038.16 AEO68202.1 - 8.4 5.7 32.3 1 8.7 1.0 4.7 3 2 2 5 5 5 0 Intermediate filament protein Nudix_N_2 PF14803.1 AEO68203.1 - 1.1 8.9 4.7 4 7.2 0.2 3.4 3 0 0 3 3 3 0 Nudix N-terminal DnaJ PF00226.26 AEO68205.1 - 1.9e-10 40.2 0.3 3.5e-10 39.4 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DEAD PF00270.24 AEO68206.1 - 2.6e-43 147.4 0.0 4e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO68206.1 - 1.4e-23 82.5 0.1 1.4e-23 82.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Suf PF05843.9 AEO68206.1 - 0.53 9.9 4.9 0.88 9.2 3.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 AEO68206.1 - 9.5 4.3 28.6 13 3.8 19.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WD40 PF00400.27 AEO68207.1 - 0.078 12.9 0.2 0.99 9.4 0.1 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Cupin_5 PF06172.6 AEO68210.1 - 1.4e-41 141.6 0.0 1.6e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Cupin_5 PF06172.6 AEO68211.1 - 1e-32 112.9 0.0 1.7e-31 109.0 0.0 2.0 1 1 0 1 1 1 1 Cupin superfamily (DUF985) Fungal_trans PF04082.13 AEO68212.1 - 1.6e-06 27.2 0.0 2.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1479 PF07350.7 AEO68213.1 - 4.3e-152 506.4 0.0 5.5e-152 506.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 AEO68213.1 - 0.002 18.1 0.1 0.23 11.4 0.1 2.5 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Peptidase_S31 PF05578.7 AEO68213.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 DUF1993 PF09351.5 AEO68214.1 - 5.7e-46 156.3 0.0 6.5e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Glyco_hydro_30 PF02055.11 AEO68216.1 - 8.6e-53 179.2 1.7 1.2e-52 178.7 1.2 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 AEO68216.1 - 0.0025 16.7 0.0 0.0044 16.0 0.0 1.3 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF3050 PF11251.3 AEO68216.1 - 0.0061 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) Ank_2 PF12796.2 AEO68218.1 - 8.2e-10 38.8 0.0 0.00012 22.3 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 AEO68218.1 - 1.4e-08 34.1 0.6 0.26 11.1 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 AEO68218.1 - 2.5e-08 33.3 0.0 0.1 12.8 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 AEO68218.1 - 8.9e-07 29.2 0.3 0.01 16.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO68218.1 - 0.0088 16.2 0.1 1.7 8.9 0.1 3.3 2 1 0 2 2 2 1 Ankyrin repeats (many copies) CBM_19 PF03427.8 AEO68219.1 - 0.00076 19.2 8.8 0.015 15.0 0.7 2.5 2 1 0 2 2 2 2 Carbohydrate binding domain (family 19) p450 PF00067.17 AEO68221.1 - 2.1e-30 105.6 0.0 1.1e-16 60.4 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 PYRIN PF02758.11 AEO68221.1 - 0.06 13.0 0.5 0.14 11.9 0.3 1.6 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain Glyco_hydro_10 PF00331.15 AEO68222.1 - 3.1e-103 345.1 4.0 3.8e-103 344.8 2.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 AEO68222.1 - 1.7e-13 49.9 13.5 5.7e-13 48.2 9.4 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain adh_short PF00106.20 AEO68223.1 - 1.1e-13 51.4 0.1 2.8e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO68223.1 - 6.3e-05 22.7 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO68223.1 - 0.0044 16.8 0.0 0.0061 16.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Amidase02_C PF12123.3 AEO68223.1 - 0.021 14.4 0.0 1.5 8.5 0.0 2.4 1 1 1 2 2 2 0 N-acetylmuramoyl-l-alanine amidase NAD_binding_10 PF13460.1 AEO68223.1 - 0.051 13.5 0.1 0.22 11.5 0.1 2.0 1 1 0 1 1 1 0 NADH(P)-binding Beta-lactamase PF00144.19 AEO68224.1 - 3.4e-38 131.5 0.0 6.2e-38 130.6 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 AEO68224.1 - 0.00023 20.5 0.0 0.00039 19.7 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase DUF2263 PF10021.4 AEO68225.1 - 4.2e-15 56.0 0.0 9.4e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) DUF4222 PF13973.1 AEO68226.1 - 0.12 11.7 0.2 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4222) Pkinase PF00069.20 AEO68227.1 - 4.9e-25 88.1 0.0 7.9e-25 87.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO68227.1 - 5.9e-08 32.0 0.0 0.0005 19.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 AEO68227.1 - 0.052 12.3 0.1 0.073 11.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1996 PF09362.5 AEO68228.1 - 1.5e-91 306.2 0.4 1.9e-91 305.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) zf-C2H2_4 PF13894.1 AEO68229.1 - 2.7e-06 27.3 22.9 0.17 12.2 0.4 5.7 4 1 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 AEO68229.1 - 0.0012 18.9 4.8 23 5.3 0.4 4.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 AEO68229.1 - 0.1 12.9 0.2 0.1 12.9 0.1 4.8 5 1 1 6 6 6 0 Zinc finger, C2H2 type zf-CSL PF05207.8 AEO68229.1 - 0.24 10.9 0.8 0.87 9.1 0.1 2.1 2 0 0 2 2 2 0 CSL zinc finger zf-C2H2_2 PF12756.2 AEO68229.1 - 0.48 10.5 9.6 11 6.2 1.6 3.8 4 1 0 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 AEO68229.1 - 0.98 9.4 6.7 0.58 10.1 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO68229.1 - 3.9 7.7 9.4 12 6.1 0.2 4.5 4 1 1 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 AEO68229.1 - 3.9 7.6 14.0 1 9.5 0.7 4.0 4 1 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding Nop PF01798.13 AEO68230.1 - 7.3e-56 187.6 0.1 1.2e-55 186.9 0.1 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 AEO68230.1 - 9.8e-22 76.5 0.0 2.2e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 AEO68230.1 - 5.7e-20 71.2 0.0 2.6e-19 69.1 0.0 2.2 1 0 0 1 1 1 1 NOP5NT (NUC127) domain PcfK PF14058.1 AEO68230.1 - 0.0041 17.2 9.3 0.0076 16.3 6.4 1.4 1 0 0 1 1 1 1 PcfK-like protein Topoisom_I_N PF02919.10 AEO68230.1 - 0.56 9.4 12.2 0.91 8.7 8.4 1.3 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment RNA_polI_A34 PF08208.6 AEO68230.1 - 3 7.4 32.2 5.1 6.7 22.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 YqfQ PF14181.1 AEO68230.1 - 8 6.4 11.7 18 5.3 8.1 1.6 1 0 0 1 1 1 0 YqfQ-like protein AAA PF00004.24 AEO68231.1 - 5e-43 146.4 0.0 9.2e-43 145.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 AEO68231.1 - 8.2e-28 96.0 0.1 5e-27 93.5 0.1 2.4 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 AEO68231.1 - 3.2e-21 74.9 4.9 8.4e-21 73.6 3.0 2.1 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 AEO68231.1 - 3.8e-06 27.7 0.7 3.4e-05 24.6 0.0 2.8 3 2 0 3 3 2 1 AAA domain AAA_25 PF13481.1 AEO68231.1 - 5.6e-06 25.8 1.0 0.13 11.6 0.1 3.3 1 1 2 3 3 3 2 AAA domain RuvB_N PF05496.7 AEO68231.1 - 9.6e-06 24.8 0.0 1.9e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AEO68231.1 - 1.4e-05 25.2 0.1 0.0016 18.6 0.1 2.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AEO68231.1 - 2.3e-05 23.9 0.0 5.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 AEO68231.1 - 3.3e-05 23.6 0.0 0.00023 20.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AEO68231.1 - 3.3e-05 23.7 0.0 7.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 AEO68231.1 - 4.9e-05 23.4 0.0 0.011 15.9 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 AEO68231.1 - 7.7e-05 22.7 0.2 0.0014 18.6 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 AEO68231.1 - 0.00015 20.6 0.0 0.00025 19.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 AEO68231.1 - 0.00021 21.1 0.0 0.00069 19.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 AEO68231.1 - 0.00041 19.3 0.0 0.0014 17.6 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 AEO68231.1 - 0.0011 18.8 0.0 0.0051 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 AEO68231.1 - 0.0044 16.1 0.2 0.15 11.0 0.1 2.8 2 1 0 2 2 2 1 Zeta toxin AAA_24 PF13479.1 AEO68231.1 - 0.0062 16.1 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO68231.1 - 0.01 16.1 0.1 0.033 14.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 AEO68231.1 - 0.015 14.9 0.0 0.37 10.4 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Torsin PF06309.6 AEO68231.1 - 0.024 14.4 0.1 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Torsin Mg_chelatase PF01078.16 AEO68231.1 - 0.025 13.7 0.0 0.065 12.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 AEO68231.1 - 0.033 13.8 0.4 0.2 11.3 0.0 2.3 2 1 1 3 3 2 0 Archaeal ATPase ResIII PF04851.10 AEO68231.1 - 0.041 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 AEO68231.1 - 0.043 13.0 0.0 0.099 11.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 AEO68231.1 - 0.057 12.2 0.0 0.099 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.1 AEO68231.1 - 0.065 12.9 0.0 0.065 12.9 0.0 2.2 2 0 0 2 2 1 0 Part of AAA domain AAA_21 PF13304.1 AEO68231.1 - 0.076 12.9 0.2 3.3 7.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 AEO68231.1 - 0.1 12.5 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain CPT PF07931.7 AEO68231.1 - 0.11 12.0 0.0 0.55 9.8 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Peptidase_M28 PF04389.12 AEO68231.1 - 0.11 12.1 0.0 0.88 9.2 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M28 Guanylate_kin PF00625.16 AEO68231.1 - 0.12 11.8 0.0 0.41 10.0 0.0 2.0 1 0 0 1 1 1 0 Guanylate kinase Sigma54_activat PF00158.21 AEO68231.1 - 0.13 11.7 0.6 0.39 10.1 0.0 2.2 2 1 0 2 2 1 0 Sigma-54 interaction domain KaiC PF06745.8 AEO68231.1 - 0.13 11.3 0.1 5.6 5.9 0.0 2.7 2 1 1 3 3 3 0 KaiC Prefoldin_2 PF01920.15 AEO68232.1 - 2.4e-21 75.5 14.2 2.9e-21 75.2 9.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 AEO68232.1 - 0.0018 17.9 12.2 0.0078 15.8 1.7 2.2 2 0 0 2 2 2 2 Prefoldin subunit Prefoldin_3 PF13758.1 AEO68232.1 - 0.0086 15.8 4.9 0.012 15.3 3.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF1732 PF08340.6 AEO68232.1 - 0.0098 15.6 1.1 0.19 11.5 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1732) YgaB PF14182.1 AEO68232.1 - 0.021 15.0 3.7 0.021 15.0 2.6 2.3 2 1 0 2 2 2 0 YgaB-like protein Atg14 PF10186.4 AEO68232.1 - 0.025 13.5 9.6 0.036 13.0 6.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 AEO68232.1 - 0.033 14.0 14.1 0.29 10.9 3.1 2.1 2 0 0 2 2 2 0 Tropomyosin like Lzipper-MIP1 PF14389.1 AEO68232.1 - 0.045 13.8 6.9 0.45 10.6 1.6 2.2 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF4201 PF13870.1 AEO68232.1 - 0.054 12.9 9.7 0.45 9.9 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) IncA PF04156.9 AEO68232.1 - 0.065 12.8 15.2 0.91 9.0 10.5 2.0 1 1 0 1 1 1 0 IncA protein DUF2702 PF10863.3 AEO68232.1 - 0.079 12.6 4.4 0.11 12.2 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2702) DivIC PF04977.10 AEO68232.1 - 0.08 12.4 15.8 0.49 9.9 4.3 3.2 2 2 0 2 2 2 0 Septum formation initiator Val_tRNA-synt_C PF10458.4 AEO68232.1 - 0.096 12.7 0.7 0.096 12.7 0.5 3.2 2 1 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Vac_Fusion PF02346.11 AEO68232.1 - 0.11 11.9 0.8 5.1 6.6 0.1 2.4 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Spc7 PF08317.6 AEO68232.1 - 0.12 11.0 10.5 0.13 10.8 7.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein BRE1 PF08647.6 AEO68232.1 - 0.21 11.6 7.6 3.6 7.6 0.3 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Nup54 PF13874.1 AEO68232.1 - 0.21 11.2 7.8 3.2 7.3 2.2 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF4164 PF13747.1 AEO68232.1 - 0.24 11.5 5.4 5.6 7.1 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Occludin_ELL PF07303.8 AEO68232.1 - 0.29 11.8 7.1 0.51 11.1 3.3 2.0 1 1 1 2 2 2 0 Occludin homology domain Uds1 PF15456.1 AEO68232.1 - 0.34 10.9 4.7 0.67 9.9 3.2 1.6 1 1 0 1 1 1 0 Up-regulated During Septation Sas10_Utp3 PF04000.10 AEO68232.1 - 0.43 10.8 6.0 0.59 10.3 1.2 2.3 2 1 0 2 2 2 0 Sas10/Utp3/C1D family ERp29 PF07749.7 AEO68232.1 - 0.44 11.2 6.5 4.1 8.1 4.5 2.2 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF737 PF05300.6 AEO68232.1 - 0.49 10.3 11.1 1.5 8.7 7.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF737) GAS PF13851.1 AEO68232.1 - 0.56 9.3 13.2 7.2 5.7 8.8 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF677 PF05055.7 AEO68232.1 - 0.56 8.8 6.8 1.5 7.3 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF677) Mnd1 PF03962.10 AEO68232.1 - 0.63 9.6 12.1 1.1 8.8 1.2 2.0 1 1 1 2 2 2 0 Mnd1 family Tektin PF03148.9 AEO68232.1 - 0.65 8.4 11.5 1.5 7.2 2.0 2.0 2 0 0 2 2 2 0 Tektin family COG2 PF06148.6 AEO68232.1 - 0.75 9.6 5.8 4.7 7.0 0.6 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Fib_alpha PF08702.5 AEO68232.1 - 0.99 9.5 6.4 1.5 8.9 0.3 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 AEO68232.1 - 1 9.6 5.1 1 9.6 1.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-Q PF13094.1 AEO68232.1 - 1.3 9.0 9.3 2.1 8.3 6.4 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CASP_C PF08172.7 AEO68232.1 - 1.8 7.4 6.0 5.1 6.0 0.2 2.1 2 0 0 2 2 2 0 CASP C terminal Cob_adeno_trans PF01923.13 AEO68232.1 - 2.7 7.7 6.6 3.4 7.4 0.2 2.0 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Spc24 PF08286.6 AEO68232.1 - 3.2 7.4 11.0 2.8 7.6 3.3 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Fez1 PF06818.10 AEO68232.1 - 3.3 7.6 12.1 0.28 11.2 0.5 2.2 1 1 1 2 2 2 0 Fez1 YlqD PF11068.3 AEO68232.1 - 4.3 7.3 18.6 0.19 11.7 2.4 2.1 1 1 1 2 2 2 0 YlqD protein Cut12 PF11500.3 AEO68232.1 - 5.4 6.6 7.7 5.8 6.5 0.7 2.2 2 1 0 2 2 2 0 Spindle pole body formation-associated protein FlaC_arch PF05377.6 AEO68232.1 - 5.6 6.9 5.7 22 5.0 0.3 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF3847 PF12958.2 AEO68232.1 - 5.6 6.7 10.9 2.5 7.9 2.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) DUF4140 PF13600.1 AEO68232.1 - 6.2 7.3 8.1 8.1 6.9 1.4 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Allexi_40kDa PF05549.6 AEO68232.1 - 6.2 6.0 5.6 8.1 5.6 0.3 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF972 PF06156.8 AEO68232.1 - 6.7 7.1 9.4 10 6.5 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) JAB PF01398.16 AEO68234.1 - 4.1e-16 58.7 0.0 6.8e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 AEO68234.1 - 3.9e-06 26.3 0.0 1.4e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.6 AEO68234.1 - 0.0024 17.8 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain HET PF06985.6 AEO68236.1 - 8.7e-15 55.0 4.5 2.5e-14 53.5 1.5 2.9 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) DMA PF03474.9 AEO68236.1 - 0.41 10.5 2.4 0.35 10.7 0.1 2.0 2 0 0 2 2 2 0 DMRTA motif GMC_oxred_N PF00732.14 AEO68237.1 - 1.3e-50 172.2 0.9 3.3e-50 170.9 0.2 1.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO68237.1 - 2.6e-28 99.0 0.0 5.6e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 AEO68237.1 - 8.2e-05 21.6 7.9 0.00055 18.9 5.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO68237.1 - 0.0015 18.5 0.4 0.0042 17.0 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AEO68237.1 - 0.038 13.8 0.4 2.2 8.1 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO68237.1 - 0.18 10.6 0.1 0.28 10.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 AEO68237.1 - 0.72 8.6 7.1 1.8 7.3 4.9 1.6 1 1 0 1 1 1 0 FAD binding domain adh_short PF00106.20 AEO68238.1 - 0.0042 17.0 0.2 0.006 16.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase OPT PF03169.10 AEO68239.1 - 6.9e-184 612.7 47.2 7.9e-184 612.5 32.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein adh_short PF00106.20 AEO68240.1 - 1.1e-14 54.7 0.0 1.6e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO68240.1 - 9.9e-07 28.5 0.0 1.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO68240.1 - 0.002 17.9 0.0 0.0029 17.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 AEO68240.1 - 0.006 16.6 0.0 0.022 14.7 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO68240.1 - 0.0082 15.6 0.0 0.019 14.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 AEO68240.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_31 PF13847.1 AEO68241.1 - 2.4e-26 92.1 0.0 4.4e-26 91.2 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO68241.1 - 1e-24 86.7 0.1 2.3e-24 85.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO68241.1 - 4.8e-18 65.1 0.0 7e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 AEO68241.1 - 1.1e-16 61.3 0.0 1.9e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO68241.1 - 1.6e-16 60.4 0.0 2.5e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO68241.1 - 9.3e-16 58.1 0.0 1.6e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO68241.1 - 7.5e-14 51.7 0.5 1.5e-13 50.7 0.4 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO68241.1 - 2.9e-13 49.8 0.0 3.8e-13 49.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AEO68241.1 - 1.2e-12 47.7 0.0 1.8e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 AEO68241.1 - 6.2e-09 35.4 0.0 9.8e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 AEO68241.1 - 9.4e-09 34.9 0.1 2.5e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW GCD14 PF08704.5 AEO68241.1 - 2e-08 34.0 0.0 3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_24 PF13578.1 AEO68241.1 - 1.7e-07 32.0 0.6 3.5e-07 31.0 0.1 1.7 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 AEO68241.1 - 2.5e-07 30.1 0.0 4.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.12 AEO68241.1 - 1.7e-06 27.2 0.0 2.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.15 AEO68241.1 - 3.4e-06 26.3 0.0 4.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.15 AEO68241.1 - 5.6e-06 25.5 0.0 9.1e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.11 AEO68241.1 - 2.1e-05 23.0 0.0 3.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.6 AEO68241.1 - 6.4e-05 21.7 0.0 9.2e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 AEO68241.1 - 0.00022 20.9 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 AEO68241.1 - 0.00025 21.1 0.2 0.00064 19.7 0.1 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase UPF0020 PF01170.13 AEO68241.1 - 0.00044 19.8 0.0 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 AEO68241.1 - 0.00047 19.2 0.0 0.00089 18.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_15 PF09445.5 AEO68241.1 - 0.001 18.6 0.0 0.002 17.6 0.0 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TehB PF03848.9 AEO68241.1 - 0.0016 17.6 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_19 PF04672.7 AEO68241.1 - 0.003 16.8 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl methyltransferase ADH_zinc_N PF00107.21 AEO68241.1 - 0.0046 16.4 0.3 0.012 15.1 0.2 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FmrO PF07091.6 AEO68241.1 - 0.0099 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) TrkA_N PF02254.13 AEO68241.1 - 0.013 15.5 0.1 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain FumaraseC_C PF10415.4 AEO68241.1 - 0.014 15.4 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 Fumarase C C-terminus Methyltransf_16 PF10294.4 AEO68241.1 - 0.019 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Met_10 PF02475.11 AEO68241.1 - 0.034 13.7 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_20 PF12147.3 AEO68241.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_8 PF05148.10 AEO68241.1 - 0.082 12.5 0.0 0.5 9.9 0.0 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase Peroxidase_2 PF01328.12 AEO68242.1 - 1.4e-45 155.3 0.2 1.8e-45 154.9 0.2 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 ARGLU PF15346.1 AEO68247.1 - 0.56 9.9 34.4 0.6 9.8 23.9 1.0 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Borrelia_P83 PF05262.6 AEO68247.1 - 2 6.5 16.8 2.4 6.2 11.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2361 PF10153.4 AEO68247.1 - 5.4 7.2 17.7 2.3 8.4 5.3 2.2 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2361) Exonuc_VII_L PF02601.10 AEO68247.1 - 6.7 5.7 10.2 7.3 5.6 7.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_13 PF13166.1 AEO68247.1 - 7.2 4.9 10.8 9.1 4.5 7.5 1.2 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 AEO68248.1 - 2.3e-23 82.4 51.6 8.6e-17 60.8 17.9 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 AEO68248.1 - 1.5e-05 23.4 25.3 2.2e-05 22.8 17.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 AEO68248.1 - 0.42 10.6 5.6 0.28 11.1 1.0 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 RVT_1 PF00078.22 AEO68249.1 - 0.13 11.5 0.6 0.2 11.0 0.4 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_2 PF12796.2 AEO68252.1 - 8.6e-32 109.3 15.4 4.2e-15 55.8 0.9 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 AEO68252.1 - 4.1e-21 73.6 11.8 2.9e-07 29.9 0.3 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 AEO68252.1 - 1.1e-20 73.5 12.7 2.3e-09 37.5 0.2 4.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO68252.1 - 2.7e-16 59.2 13.6 5.5e-07 29.6 0.7 4.5 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO68252.1 - 3.3e-16 57.7 9.3 0.00022 21.1 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Fungal_trans PF04082.13 AEO68254.1 - 5e-36 123.9 0.0 1.1e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO68254.1 - 3.3e-08 33.2 6.4 6.8e-08 32.3 4.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NPV_P10 PF05531.7 AEO68255.1 - 0.087 13.0 0.0 0.96 9.7 0.0 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein His_Phos_1 PF00300.17 AEO68257.1 - 2.5e-20 73.1 0.0 3.4e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Tetraspannin PF00335.15 AEO68258.1 - 0.019 14.2 8.6 0.24 10.6 6.0 2.0 1 1 0 1 1 1 0 Tetraspanin family GWT1 PF06423.7 AEO68258.1 - 0.021 14.9 4.4 0.031 14.3 3.1 1.4 1 0 0 1 1 1 0 GWT1 FUSC-like PF12805.2 AEO68258.1 - 0.044 12.7 2.6 0.073 11.9 1.8 1.4 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DctQ PF04290.7 AEO68258.1 - 0.11 12.2 7.3 0.69 9.6 0.4 2.8 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component CytochromB561_N PF09786.4 AEO68258.1 - 0.21 9.9 0.3 0.29 9.5 0.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Claudin_3 PF06653.6 AEO68258.1 - 0.55 9.9 7.8 0.27 10.9 1.0 2.3 2 1 0 2 2 2 0 Tight junction protein, Claudin-like DUF2069 PF09842.4 AEO68258.1 - 1.2 9.1 5.8 2.3 8.2 3.9 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2069) Adeno_E3_14_5 PF04834.7 AEO68258.1 - 1.5 9.2 0.0 1.5 9.2 0.0 2.8 4 0 0 4 4 3 0 Early E3 14.5 kDa protein DUF1282 PF06930.7 AEO68258.1 - 1.6 8.3 11.4 2.3 7.8 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) NfeD PF01957.13 AEO68258.1 - 1.9 8.5 7.2 1.3 9.1 0.3 2.2 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding DUF4583 PF15190.1 AEO68258.1 - 2.2 7.9 6.3 1.4 8.5 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4583) OAD_gamma PF04277.8 AEO68260.1 - 0.027 14.8 7.0 0.027 14.8 4.9 1.5 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF1510 PF07423.6 AEO68260.1 - 0.09 12.1 10.2 0.11 11.8 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TEBP_beta PF07404.6 AEO68260.1 - 0.14 11.2 7.6 0.17 10.9 5.3 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Ribosomal_60s PF00428.14 AEO68260.1 - 0.19 12.1 9.0 0.32 11.4 6.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein YqfQ PF14181.1 AEO68260.1 - 0.63 10.0 6.4 0.71 9.9 4.4 1.2 1 0 0 1 1 1 0 YqfQ-like protein PPP4R2 PF09184.6 AEO68260.1 - 0.66 9.4 9.1 0.88 9.0 6.3 1.1 1 0 0 1 1 1 0 PPP4R2 RNA_polI_A34 PF08208.6 AEO68260.1 - 0.99 9.0 15.4 1.1 8.9 10.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.12 AEO68260.1 - 1.4 8.6 4.4 1.7 8.4 3.1 1.1 1 0 0 1 1 1 0 DDHD domain Sec62 PF03839.11 AEO68260.1 - 4.2 6.7 7.3 5.2 6.4 5.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Tom22 PF04281.8 AEO68260.1 - 9.6 5.7 7.9 17 4.9 5.5 1.6 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 AAA_11 PF13086.1 AEO68261.1 - 1.3e-08 34.7 0.0 2.2e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.1 AEO68261.1 - 3.9e-08 32.9 0.0 2.8e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 AEO68261.1 - 0.00022 20.8 0.1 0.00072 19.1 0.0 1.9 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 AEO68261.1 - 0.0065 16.0 0.1 0.081 12.4 0.0 2.6 2 1 2 4 4 4 1 AAA domain zf-CCHC PF00098.18 AEO68262.1 - 0.0064 16.3 2.3 0.0064 16.3 1.6 5.5 5 1 1 6 6 6 2 Zinc knuckle zf-CCHC_4 PF14392.1 AEO68262.1 - 0.27 10.9 0.2 0.27 10.9 0.1 4.0 3 1 1 4 4 4 0 Zinc knuckle Kelch_4 PF13418.1 AEO68263.1 - 6.8e-15 54.5 14.9 0.00018 21.2 0.2 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 AEO68263.1 - 5.6e-11 42.1 12.2 0.0043 16.9 0.1 5.6 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 AEO68263.1 - 5e-09 35.9 7.6 0.014 15.5 0.0 5.8 5 1 1 6 6 6 2 Kelch motif Kelch_2 PF07646.10 AEO68263.1 - 2.1e-06 27.2 11.1 0.056 13.2 0.2 5.8 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.1 AEO68263.1 - 4.3e-05 23.5 19.3 0.02 15.0 0.3 6.9 8 0 0 8 8 8 2 Galactose oxidase, central domain Kelch_1 PF01344.20 AEO68263.1 - 0.013 15.0 1.0 4.2 6.9 0.0 4.1 4 0 0 4 4 4 0 Kelch motif PQQ_3 PF13570.1 AEO68263.1 - 0.05 13.8 7.6 0.085 13.1 0.1 4.0 3 1 0 3 3 3 0 PQQ-like domain MARVEL PF01284.18 AEO68264.1 - 1.3e-08 34.7 3.7 2.1e-08 34.1 2.6 1.3 1 1 0 1 1 1 1 Membrane-associating domain Serinc PF03348.10 AEO68264.1 - 0.099 11.3 0.1 0.099 11.3 0.1 1.9 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF2975 PF11188.3 AEO68264.1 - 5.9 6.6 9.3 7.7 6.2 2.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) adh_short PF00106.20 AEO68265.1 - 2.1e-29 102.5 2.5 3.2e-29 102.0 1.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO68265.1 - 4.3e-26 92.1 0.1 5.1e-26 91.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO68265.1 - 1.5e-13 50.8 1.0 2.1e-13 50.3 0.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO68265.1 - 5.2e-05 22.7 0.5 0.0033 16.8 0.3 2.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.16 AEO68265.1 - 0.018 14.8 0.4 0.048 13.5 0.1 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Saccharop_dh PF03435.13 AEO68265.1 - 0.071 12.0 0.3 0.098 11.6 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase THF_DHG_CYH_C PF02882.14 AEO68265.1 - 0.076 12.0 0.1 0.21 10.6 0.1 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2507 PF10702.4 AEO68265.1 - 0.13 11.9 0.1 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2507) zf-C2H2 PF00096.21 AEO68266.1 - 6.3e-10 38.7 18.7 0.00024 21.2 3.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO68266.1 - 6.4e-08 32.5 12.1 0.00014 21.9 0.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO68266.1 - 0.0011 19.1 17.8 0.6 10.5 0.2 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger Bunya_G2 PF03563.8 AEO68266.1 - 0.77 8.5 3.1 1.1 8.0 2.2 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-C2H2_6 PF13912.1 AEO68266.1 - 1.6 8.7 9.3 0.27 11.2 0.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Fructosamin_kin PF03881.9 AEO68267.1 - 1e-33 116.5 0.1 1.2e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 AEO68267.1 - 0.00015 21.6 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 AEO68267.1 - 0.066 12.3 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase PGAP1 PF07819.8 AEO68268.1 - 2.7e-06 27.1 0.0 7.4e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.7 AEO68268.1 - 3.3e-06 26.8 0.0 6.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.9 AEO68268.1 - 2.9e-05 23.4 0.0 6.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 AEO68268.1 - 8.3e-05 22.5 0.1 0.00029 20.7 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_16 PF13191.1 AEO68268.1 - 0.003 17.5 0.1 0.012 15.5 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_5 PF12695.2 AEO68268.1 - 0.0048 16.6 0.0 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family WD40 PF00400.27 AEO68268.1 - 0.038 13.8 0.8 21 5.2 0.0 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat AAA_22 PF13401.1 AEO68268.1 - 0.16 12.1 0.0 1.1 9.3 0.0 2.5 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 AEO68268.1 - 0.37 9.5 0.0 0.7 8.6 0.0 1.3 1 0 0 1 1 1 0 ArgK protein zf-MYND PF01753.13 AEO68269.1 - 4e-10 39.3 10.8 8.5e-10 38.3 7.5 1.6 1 0 0 1 1 1 1 MYND finger DUF4470 PF14737.1 AEO68269.1 - 4.2e-08 32.8 0.5 5e-06 26.1 0.3 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) WSC PF01822.14 AEO68270.1 - 1e-12 47.8 10.4 1e-12 47.8 7.2 1.8 2 0 0 2 2 2 1 WSC domain DUF4448 PF14610.1 AEO68270.1 - 0.00034 20.1 0.0 0.00056 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Podoplanin PF05808.6 AEO68270.1 - 0.0046 16.5 0.5 0.0075 15.8 0.3 1.2 1 0 0 1 1 1 1 Podoplanin CSF-1 PF05337.6 AEO68270.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) ECH PF00378.15 AEO68271.1 - 2e-45 154.8 0.0 5.4e-43 146.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family PNMA PF14893.1 AEO68271.1 - 0.11 11.5 1.0 0.17 10.8 0.7 1.2 1 0 0 1 1 1 0 PNMA CsbD PF05532.7 AEO68272.1 - 0.0098 15.5 23.1 0.051 13.2 13.3 3.5 1 1 1 2 2 2 1 CsbD-like ISG65-75 PF11727.3 AEO68272.1 - 0.02 13.9 7.7 0.033 13.2 5.3 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF883 PF05957.8 AEO68272.1 - 0.042 14.2 6.4 0.12 12.8 2.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 AEO68272.1 - 0.15 12.4 8.4 29 5.1 5.8 2.7 1 1 0 1 1 1 0 YtxH-like protein LEA_4 PF02987.11 AEO68272.1 - 0.86 9.5 23.8 0.4 10.5 5.1 3.5 3 1 1 4 4 4 0 Late embryogenesis abundant protein ketoacyl-synt PF00109.21 AEO68274.1 - 2.1e-72 243.6 0.1 6.2e-72 242.1 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 AEO68274.1 - 4.4e-64 216.8 0.4 9.4e-64 215.7 0.3 1.6 1 0 0 1 1 1 1 Acyl transferase domain Carn_acyltransf PF00755.15 AEO68274.1 - 7.2e-59 199.3 0.0 1e-58 198.9 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PS-DH PF14765.1 AEO68274.1 - 1.7e-49 168.5 9.6 1.7e-49 168.5 6.7 2.5 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.5 AEO68274.1 - 3.6e-39 134.3 0.1 3.6e-39 134.3 0.1 3.4 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 AEO68274.1 - 7.4e-34 117.0 0.3 7.4e-34 117.0 0.2 4.0 4 0 0 4 4 4 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 AEO68274.1 - 4.8e-33 113.5 0.3 4.8e-33 113.5 0.2 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 AEO68274.1 - 9e-06 25.8 0.0 4.2e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 AEO68274.1 - 2.1e-05 24.9 0.1 8.4e-05 22.9 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO68274.1 - 0.00082 19.9 1.6 0.0038 17.7 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 AEO68274.1 - 0.0036 16.7 0.0 0.041 13.3 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_23 PF13489.1 AEO68274.1 - 0.0076 15.9 0.0 0.084 12.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO68274.1 - 0.54 9.3 0.0 1.2 8.2 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MFS_1 PF07690.11 AEO68276.1 - 1e-36 126.3 53.9 1.5e-35 122.5 27.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 AEO68276.1 - 2.4e-13 49.1 5.8 4.2e-13 48.3 4.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NapE PF06796.6 AEO68276.1 - 3.2 7.1 7.2 1.3 8.3 2.2 2.4 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE DUF4131 PF13567.1 AEO68276.1 - 8.1 5.8 21.4 7.6 5.9 0.1 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) NAD_binding_4 PF07993.7 AEO68277.1 - 1.2e-33 116.0 0.0 1.9e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 AEO68277.1 - 1.1e-32 112.9 0.0 1.8e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 AEO68277.1 - 1.2e-11 44.7 0.0 2.7e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 AEO68277.1 - 7.8e-11 41.8 0.0 1.7e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_deac_1 PF01522.16 AEO68279.1 - 8e-18 64.2 0.0 1.3e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase SET PF00856.23 AEO68280.1 - 2.6e-16 60.3 0.0 2.9e-15 56.9 0.0 2.0 1 1 0 1 1 1 1 SET domain Glyco_hydro_18 PF00704.23 AEO68282.1 - 3.9e-98 329.0 0.0 4.4e-98 328.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AP_endonuc_2 PF01261.19 AEO68282.1 - 0.0074 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Ribosomal_S26e PF01283.14 AEO68283.1 - 1.4e-51 173.5 9.6 1.6e-51 173.3 6.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 AEO68283.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Zn_ribbon_2 PF12674.2 AEO68283.1 - 0.047 14.0 0.3 6.6 7.1 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_7 PF12838.2 AEO68283.1 - 0.085 13.2 2.2 1.2 9.6 0.4 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain Ank PF00023.25 AEO68284.1 - 1e-42 141.8 10.1 1.4e-08 34.1 0.0 9.8 10 0 0 10 10 10 6 Ankyrin repeat Ank_2 PF12796.2 AEO68284.1 - 6.1e-41 138.6 0.0 7.1e-10 39.0 0.0 6.9 4 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AEO68284.1 - 1.2e-32 108.6 9.7 0.00018 21.4 0.0 10.3 12 0 0 12 12 12 6 Ankyrin repeat Ank_4 PF13637.1 AEO68284.1 - 1.1e-25 89.5 7.9 4.2e-07 30.2 0.0 7.7 8 1 0 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO68284.1 - 1.5e-23 82.2 10.6 3.5e-05 23.8 0.2 8.5 6 2 2 8 8 8 5 Ankyrin repeats (many copies) F-box-like PF12937.2 AEO68284.1 - 3e-07 30.0 0.0 1e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO68284.1 - 0.00038 20.0 0.0 0.003 17.1 0.0 2.5 2 0 0 2 2 2 1 F-box domain Dicty_CAD PF05720.7 AEO68284.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Cell-cell adhesion domain Cpn60_TCP1 PF00118.19 AEO68285.1 - 3.2e-143 477.8 3.7 3.7e-143 477.6 2.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Acetyltransf_1 PF00583.19 AEO68286.1 - 5.9e-05 23.0 0.0 9.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 AEO68286.1 - 8.3e-05 22.5 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AEO68286.1 - 0.0017 18.5 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO68286.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S2 PF00318.15 AEO68287.1 - 3.6e-49 166.8 0.0 6.9e-49 165.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S2 CBS PF00571.23 AEO68287.1 - 1e-38 130.8 10.3 3.4e-10 39.5 0.0 5.6 6 0 0 6 6 6 4 CBS domain PB1 PF00564.19 AEO68287.1 - 2.1e-08 33.7 0.0 7.7e-08 31.8 0.0 2.0 2 0 0 2 2 2 1 PB1 domain DUF1191 PF06697.7 AEO68288.1 - 2.2e-06 26.6 0.0 2.9e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 AEO68288.1 - 0.0092 16.3 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 AEO68288.1 - 0.021 14.5 0.0 0.025 14.3 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family Lysis_S PF04971.7 AEO68288.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Lysis protein S MFS_1 PF07690.11 AEO68289.1 - 7.3e-22 77.5 6.6 8.3e-22 77.3 4.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO68289.1 - 9.4e-06 24.4 2.4 1.1e-05 24.2 1.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.3 AEO68289.1 - 0.0019 16.7 0.5 0.23 9.8 0.0 2.0 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like zf-CCCH PF00642.19 AEO68290.1 - 6.8e-07 28.8 12.9 0.00044 19.8 0.5 3.5 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SpoIISB_antitox PF14185.1 AEO68290.1 - 0.011 15.4 0.2 0.025 14.3 0.1 1.6 1 0 0 1 1 1 0 Antitoxin SpoIISB, type II toxin-antitoxin system IncA PF04156.9 AEO68290.1 - 4.7 6.7 6.4 6.9 6.2 4.4 1.2 1 0 0 1 1 1 0 IncA protein DUF1744 PF08490.7 AEO68291.1 - 1.6e-157 524.1 0.0 2.3e-157 523.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 AEO68291.1 - 4.8e-65 219.5 0.1 7.8e-65 218.8 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 AEO68291.1 - 3.3e-21 75.6 0.1 1e-20 73.9 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 AEO68291.1 - 1.8e-09 37.4 0.2 4.3e-09 36.2 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 AEO68291.1 - 2.6e-05 24.1 0.0 8.9e-05 22.3 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily DUF3767 PF12597.3 AEO68292.1 - 2.1e-39 133.8 0.0 4.5e-39 132.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) Pex14_N PF04695.8 AEO68292.1 - 0.0032 17.4 3.6 0.0032 17.4 2.5 1.8 1 1 1 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IDO PF01231.13 AEO68292.1 - 0.034 12.6 1.5 0.049 12.0 1.0 1.1 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase DUF533 PF04391.7 AEO68292.1 - 0.053 12.8 0.3 0.053 12.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF533) DUF4337 PF14235.1 AEO68292.1 - 3.8 7.3 6.1 7.3 6.3 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) F-box PF00646.28 AEO68294.1 - 0.00053 19.5 0.5 0.032 13.9 0.1 3.3 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 AEO68294.1 - 0.0024 17.5 0.1 0.015 14.9 0.0 2.4 2 0 0 2 2 2 1 F-box-like Glyco_hydro_12 PF01670.11 AEO68296.1 - 5e-54 182.3 1.5 5e-54 182.3 1.0 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 PAN_3 PF08277.7 AEO68297.1 - 0.027 14.1 0.6 0.069 12.7 0.1 1.9 2 0 0 2 2 2 0 PAN-like domain AAL_decarboxy PF03306.8 AEO68299.1 - 2.7e-75 252.1 0.5 3.1e-75 251.9 0.3 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase DUF1917 PF08939.5 AEO68300.1 - 4.3e-56 190.3 0.0 4.9e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) DUF3359 PF11839.3 AEO68301.1 - 0.004 17.4 2.0 0.004 17.4 1.4 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3359) Med9 PF07544.8 AEO68301.1 - 0.12 12.0 1.7 0.3 10.8 1.2 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Herpes_BLRF2 PF05812.7 AEO68301.1 - 0.16 11.8 3.1 0.52 10.1 2.1 1.9 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Arfaptin PF06456.8 AEO68302.1 - 0.021 14.2 0.2 0.029 13.7 0.1 1.2 1 0 0 1 1 1 0 Arfaptin-like domain YqcI_YcgG PF08892.6 AEO68302.1 - 0.06 12.8 0.2 0.094 12.2 0.2 1.2 1 0 0 1 1 1 0 YqcI/YcgG family GED PF02212.13 AEO68302.1 - 0.12 12.2 0.5 0.19 11.6 0.4 1.4 1 0 0 1 1 1 0 Dynamin GTPase effector domain OxoDH_E1alpha_N PF12573.3 AEO68304.1 - 0.1 12.1 0.2 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal DNA_ligase_A_M PF01068.16 AEO68305.1 - 1e-50 171.9 0.1 3.9e-48 163.5 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 AEO68305.1 - 6.5e-39 133.5 0.0 1.1e-38 132.7 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 AEO68305.1 - 5.4e-20 71.6 0.0 1.3e-18 67.2 0.0 3.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region PCI_Csn8 PF10075.4 AEO68306.1 - 3.4e-39 133.8 0.0 5.9e-39 133.1 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 AEO68306.1 - 7.4e-23 81.1 0.1 9.6e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Cpn60_TCP1 PF00118.19 AEO68307.1 - 2.2e-151 504.8 0.2 2.5e-151 504.6 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Prenylcys_lyase PF07156.9 AEO68308.1 - 6e-29 101.0 0.0 8.4e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 AEO68308.1 - 2e-13 50.1 0.3 1e-12 47.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 AEO68308.1 - 6.7e-06 25.4 0.0 1.4e-05 24.4 0.0 1.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 AEO68308.1 - 6.4e-05 22.0 0.1 0.00026 20.0 0.0 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AEO68308.1 - 7.6e-05 22.6 0.1 0.016 15.0 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO68308.1 - 0.00018 21.6 0.0 0.0015 18.6 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO68308.1 - 0.0082 15.9 0.0 0.026 14.2 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Malic_M PF03949.10 AEO68308.1 - 0.064 12.7 0.1 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Pyr_redox PF00070.22 AEO68308.1 - 0.085 13.2 0.0 0.47 10.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 AEO68308.1 - 0.1 11.2 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase VID27 PF08553.5 AEO68309.1 - 0 1153.9 0.0 0 1153.8 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Nop14 PF04147.7 AEO68309.1 - 0.14 10.0 11.2 0.22 9.4 7.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 AEO68309.1 - 8.1 4.3 10.8 13 3.6 7.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Thioredoxin_2 PF13098.1 AEO68316.1 - 0.044 13.9 0.0 0.044 13.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain DUF2945 PF11160.3 AEO68316.1 - 0.065 13.0 0.9 0.14 12.0 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2945) E1-E2_ATPase PF00122.15 AEO68317.1 - 5.8e-57 192.3 1.6 1.2e-56 191.3 1.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AEO68317.1 - 2.8e-28 99.8 0.0 1.2e-27 97.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 AEO68317.1 - 2.5e-24 85.8 15.2 4.7e-19 68.6 0.8 3.2 3 1 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 AEO68317.1 - 5.8e-20 71.0 0.0 1.5e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AEO68317.1 - 1.4e-13 51.4 0.0 2.8e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AEO68317.1 - 2.4e-13 49.3 0.1 9.6e-13 47.3 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AEO68317.1 - 0.0001 22.0 0.7 0.016 14.8 0.3 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GET2 PF08690.5 AEO68317.1 - 0.073 12.2 0.1 0.15 11.2 0.1 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 Pox_A14 PF05767.7 AEO68317.1 - 0.66 9.9 4.7 0.19 11.7 0.1 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 MFS_1 PF07690.11 AEO68318.1 - 9.1e-29 100.2 58.9 1.8e-26 92.7 14.3 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4535 PF15054.1 AEO68318.1 - 5.3 6.5 5.4 30 4.1 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) Glyco_transf_20 PF00982.16 AEO68319.1 - 4.3e-198 658.5 0.0 4.9e-198 658.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 AEO68319.1 - 0.09 12.2 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain NB-ARC PF00931.17 AEO68321.1 - 0.00039 19.3 0.0 0.00091 18.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 AEO68321.1 - 0.0013 18.7 1.2 0.0094 15.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain FliG_C PF01706.11 AEO68321.1 - 0.016 15.1 1.0 0.075 13.0 0.1 2.6 3 0 0 3 3 3 0 FliG C-terminal domain AAA_11 PF13086.1 AEO68321.1 - 0.02 14.4 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 AEO68321.1 - 0.034 12.7 0.0 0.11 11.0 0.0 1.9 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DAP3 PF10236.4 AEO68321.1 - 0.048 12.5 0.0 0.14 11.0 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2115 PF09888.4 AEO68321.1 - 0.065 13.3 0.6 1 9.4 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) AAA_22 PF13401.1 AEO68321.1 - 0.078 13.1 0.6 0.36 10.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain PIF1 PF05970.9 AEO68321.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase SNF2_N PF00176.18 AEO68322.1 - 1.7e-60 204.3 0.0 2.4e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 AEO68322.1 - 0.0018 18.1 0.0 0.0079 16.0 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Cerato-platanin PF07249.7 AEO68325.1 - 5.1e-06 26.4 0.1 1.3e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 Cerato-platanin F-box PF00646.28 AEO68326.1 - 0.00015 21.3 0.0 0.00036 20.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 AEO68326.1 - 0.0011 18.6 0.1 0.005 16.5 0.0 2.2 2 0 0 2 2 2 1 F-box-like Asparaginase_2 PF01112.13 AEO68327.1 - 1.3e-80 270.5 0.1 1.5e-80 270.3 0.0 1.0 1 0 0 1 1 1 1 Asparaginase Adaptin_N PF01602.15 AEO68330.1 - 8.7e-150 499.4 3.6 1.2e-149 499.0 2.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 AEO68330.1 - 2.7e-26 92.5 0.3 1.8e-25 89.8 0.0 2.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 AEO68330.1 - 2.9e-18 65.9 0.2 1.3e-07 31.8 0.0 5.5 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 AEO68330.1 - 5.9e-11 41.4 5.6 0.0091 16.0 0.0 6.1 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 AEO68330.1 - 3.2e-05 24.2 0.3 1.9 9.0 0.0 5.3 4 1 0 4 4 4 1 HEAT-like repeat Arm PF00514.18 AEO68330.1 - 0.0018 18.0 3.3 3.5 7.5 0.0 5.8 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat UNC45-central PF11701.3 AEO68330.1 - 0.024 14.2 0.3 0.69 9.5 0.1 2.6 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central CLASP_N PF12348.3 AEO68330.1 - 0.039 13.2 0.1 2.2 7.5 0.0 3.2 2 1 1 3 3 3 0 CLASP N terminal AF0941-like PF14591.1 AEO68330.1 - 0.079 13.0 1.8 0.25 11.4 1.0 1.9 2 0 0 2 2 2 0 AF0941-like CAAP1 PF15335.1 AEO68330.1 - 0.1 12.8 0.6 0.89 9.7 0.1 2.7 3 0 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 Aldo_ket_red PF00248.16 AEO68331.1 - 9.3e-63 211.6 0.0 1.1e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_4 PF08386.5 AEO68333.1 - 1.3e-18 66.8 0.0 4.2e-18 65.1 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 AEO68333.1 - 1.9e-16 60.3 0.0 2e-12 47.1 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AEO68333.1 - 6.1e-12 45.8 0.2 1.8e-11 44.3 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO68333.1 - 4.1e-05 23.3 0.0 0.0003 20.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chromate_transp PF02417.10 AEO68334.1 - 3e-50 170.0 35.8 5.7e-28 97.6 9.6 2.4 3 0 0 3 3 3 2 Chromate transporter DPBB_1 PF03330.13 AEO68335.1 - 7.3e-11 41.9 0.2 1.3e-10 41.0 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 AEO68335.1 - 0.0013 18.4 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 AEO68335.1 - 0.096 12.6 0.1 0.27 11.2 0.0 1.8 2 1 1 3 3 3 0 Cerato-platanin DUF3237 PF11578.3 AEO68336.1 - 6.5e-10 38.5 0.0 7.7e-06 25.2 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3237) HET PF06985.6 AEO68337.1 - 7e-31 107.2 0.0 1.2e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.19 AEO68338.1 - 3.4e-117 391.7 34.4 4e-117 391.5 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO68338.1 - 7.7e-25 87.3 36.4 2.4e-22 79.1 15.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO68338.1 - 1.1e-08 33.9 32.7 0.00024 19.6 9.4 3.4 3 1 0 3 3 3 3 MFS/sugar transport protein Inositol_P PF00459.20 AEO68339.1 - 2.6e-31 108.9 0.2 1.1e-30 106.9 0.2 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family Cupin_2 PF07883.6 AEO68339.1 - 0.025 14.0 0.7 0.05 13.1 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Amidohydro_4 PF13147.1 AEO68340.1 - 1.4e-11 44.9 0.4 1.4e-11 44.9 0.3 4.1 2 2 1 3 3 3 1 Amidohydrolase Amidohydro_1 PF01979.15 AEO68340.1 - 8.6e-07 28.9 0.1 7.6e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 AEO68340.1 - 3e-05 23.7 0.1 8.8e-05 22.2 0.1 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 AEO68340.1 - 8e-05 22.0 2.3 0.00025 20.3 0.0 2.7 3 0 0 3 3 3 1 Amidohydrolase family Kinesin PF00225.18 AEO68342.1 - 7.3e-46 156.4 0.0 7.4e-36 123.5 0.0 2.2 1 1 1 2 2 2 2 Kinesin motor domain Ish1 PF10281.4 AEO68342.1 - 0.078 13.0 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein AA_permease PF00324.16 AEO68344.1 - 1.3e-135 452.4 39.6 1.8e-135 452.0 27.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO68344.1 - 9.7e-36 123.2 39.4 1.3e-35 122.7 27.3 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 AEO68344.1 - 0.092 11.1 0.1 0.15 10.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) Glyco_hydro_31 PF01055.21 AEO68345.1 - 3.5e-165 550.1 4.7 4.4e-165 549.7 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 AEO68345.1 - 2.2e-09 37.0 0.7 2.2e-09 37.0 0.5 1.9 2 0 0 2 2 2 1 Galactose mutarotase-like Sugar_tr PF00083.19 AEO68346.1 - 3.3e-119 398.4 16.0 3.8e-119 398.2 11.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO68346.1 - 9.2e-18 64.0 39.2 1.3e-17 63.5 24.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3154 PF11351.3 AEO68346.1 - 3.4 7.4 5.5 4.8 6.9 0.6 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3154) Dioxygenase_C PF00775.16 AEO68347.1 - 1.5e-14 53.6 1.9 6e-14 51.7 1.3 2.0 1 1 0 1 1 1 1 Dioxygenase PMI_typeI PF01238.16 AEO68349.1 - 1.1e-72 245.0 0.0 6.1e-71 239.3 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 AEO68349.1 - 1.7e-05 24.2 0.2 0.0016 17.8 0.1 2.5 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.14 AEO68349.1 - 4.4e-05 23.1 0.0 0.0014 18.3 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.7 AEO68349.1 - 0.0025 17.1 0.3 0.0058 15.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding_2 PF14525.1 AEO68349.1 - 0.0062 16.1 1.4 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 AraC-binding-like domain Cupin_6 PF12852.2 AEO68349.1 - 0.016 14.8 0.3 0.41 10.2 0.0 2.4 2 0 0 2 2 2 0 Cupin DUF3292 PF11696.3 AEO68350.1 - 4.2e-216 718.7 0.0 6.5e-216 718.1 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) PRT_C PF08372.5 AEO68350.1 - 0.2 11.1 0.5 0.55 9.7 0.1 1.8 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Oxidored_molyb PF00174.14 AEO68354.1 - 5.7e-40 136.4 0.0 1.5e-39 135.1 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 AEO68354.1 - 5.9e-39 132.7 0.9 1.2e-38 131.7 0.6 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.16 AEO68354.1 - 5.9e-20 71.8 0.1 3e-19 69.5 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 AEO68354.1 - 8.9e-17 60.6 0.1 2.4e-16 59.2 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 AEO68354.1 - 1e-15 57.6 0.0 9.9e-07 28.8 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain HTH_38 PF13936.1 AEO68354.1 - 0.077 12.5 0.1 1.6 8.3 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain AAA_12 PF13087.1 AEO68356.1 - 2.4e-33 115.1 0.0 3.8e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 AEO68356.1 - 9.6e-23 80.9 0.0 2e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO68356.1 - 2.5e-06 27.1 0.1 2.1e-05 24.1 0.0 2.6 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 AEO68356.1 - 6.2e-06 26.3 1.5 1.5e-05 25.0 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.4 AEO68356.1 - 1.3e-05 24.3 0.1 0.017 14.0 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 AEO68356.1 - 0.063 12.6 0.3 0.89 8.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain FlgN PF05130.7 AEO68356.1 - 0.14 12.4 3.4 0.12 12.6 0.1 2.4 2 0 0 2 2 2 0 FlgN protein UvrD_C_2 PF13538.1 AEO68356.1 - 0.2 11.7 0.0 0.42 10.7 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Peptidase_S8 PF00082.17 AEO68358.1 - 8.2e-06 25.1 22.1 7.2e-05 22.0 15.3 2.3 1 1 0 1 1 1 1 Subtilase family Hydrophobin PF01185.13 AEO68359.1 - 0.79 10.2 12.3 12 6.3 8.5 2.2 1 1 0 1 1 1 0 Fungal hydrophobin HTH_24 PF13412.1 AEO68360.1 - 0.02 14.2 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.1 AEO68360.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain Glyco_hydro_18 PF00704.23 AEO68361.1 - 1.5e-10 41.0 0.0 2.6e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HrpA_pilin PF09589.5 AEO68361.1 - 0.017 15.5 0.1 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 HrpA pilus formation protein APH PF01636.18 AEO68363.1 - 3e-17 63.1 1.9 3.9e-17 62.7 1.3 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 AEO68363.1 - 0.23 10.0 0.0 0.29 9.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) Pyr_redox_3 PF13738.1 AEO68364.1 - 2.5e-13 50.5 0.0 4.7e-12 46.3 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AEO68364.1 - 2.6e-13 49.0 0.0 1.7e-10 39.7 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 AEO68364.1 - 4.7e-08 32.3 0.0 2.6e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 AEO68364.1 - 3.6e-07 30.2 0.0 7.3e-05 22.7 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 AEO68364.1 - 0.069 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding ketoacyl-synt PF00109.21 AEO68365.1 - 5.9e-81 271.6 0.0 1.3e-80 270.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 AEO68365.1 - 2.9e-55 187.8 0.0 6e-55 186.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 AEO68365.1 - 7.1e-48 163.2 0.1 2.4e-47 161.5 0.0 2.1 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.5 AEO68365.1 - 2.7e-41 141.2 0.0 1e-40 139.3 0.0 2.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 AEO68365.1 - 1.1e-34 119.7 2.7 2e-34 118.9 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 AEO68365.1 - 2.3e-30 104.8 0.2 1.1e-29 102.6 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 AEO68365.1 - 1e-07 32.0 0.1 2.5e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 AEO68365.1 - 0.0083 15.1 0.2 0.024 13.6 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_18 PF12847.2 AEO68365.1 - 0.089 13.3 0.0 0.35 11.4 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain DUF3143 PF11341.3 AEO68365.1 - 0.12 12.2 0.2 1 9.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3143) Methyltransf_12 PF08242.7 AEO68365.1 - 0.22 12.0 0.0 0.67 10.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 AEO68365.1 - 0.37 10.3 0.0 1.2 8.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Globin PF00042.17 AEO68366.1 - 9.8e-09 35.5 0.0 1.7e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.19 AEO68366.1 - 1.4e-06 28.3 0.0 2.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.3 AEO68366.1 - 7.7e-06 25.6 0.1 1.4e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Protoglobin NAD_binding_1 PF00175.16 AEO68366.1 - 9.1e-05 22.9 0.0 0.00018 22.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 AEO68366.1 - 0.012 15.5 0.0 11 5.9 0.0 3.0 2 1 0 3 3 3 0 Ferric reductase NAD binding domain Bac_globin PF01152.16 AEO68366.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial-like globin Glyco_hydro_28 PF00295.12 AEO68367.1 - 6.3e-28 97.6 5.6 8.5e-28 97.2 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 CBM_1 PF00734.13 AEO68367.1 - 2.2e-12 46.3 9.0 1e-11 44.2 6.2 2.3 1 0 0 1 1 1 1 Fungal cellulose binding domain Thymidylat_synt PF00303.14 AEO68369.1 - 2.3e-112 374.3 0.0 2.7e-112 374.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Glycos_transf_1 PF00534.15 AEO68370.1 - 3.4e-24 85.1 0.0 9.7e-24 83.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AEO68370.1 - 2.5e-10 40.6 0.0 8.8e-10 38.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AEO68370.1 - 0.00016 21.8 0.0 0.00037 20.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Haem_bd PF14376.1 AEO68370.1 - 0.097 12.3 0.1 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Haem-binding domain Sod_Fe_C PF02777.13 AEO68371.1 - 1.1e-40 137.6 0.1 1.9e-40 136.9 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 AEO68371.1 - 5.7e-32 109.8 0.5 9.8e-32 109.0 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sld5 PF05916.6 AEO68372.1 - 2.9e-14 53.2 0.0 3.9e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein BATS PF06968.8 AEO68373.1 - 2.2e-30 104.3 0.1 1.2e-29 101.9 0.0 2.2 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 AEO68373.1 - 2.9e-17 63.3 0.1 5.7e-17 62.3 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily MTBP_C PF14920.1 AEO68373.1 - 0.07 12.6 0.1 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 MDM2-binding DUF3405 PF11885.3 AEO68374.1 - 8.2e-149 496.0 3.7 9.5e-149 495.8 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Aldose_epim PF01263.15 AEO68377.1 - 6.7e-52 176.4 0.1 7.7e-52 176.2 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase FA_hydroxylase PF04116.8 AEO68378.1 - 5.4e-16 59.0 23.0 5.4e-16 59.0 15.9 2.2 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily DUF3638 PF12340.3 AEO68380.1 - 9.4e-87 289.7 0.1 3.3e-86 288.0 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 AEO68380.1 - 1.7e-17 62.2 1.3 3.8e-17 61.1 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Dicty_CAR PF05462.6 AEO68381.1 - 3.2e-16 59.1 7.5 3.2e-16 59.1 5.2 1.6 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 AEO68381.1 - 2.8e-10 40.0 9.4 5e-10 39.2 6.5 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 AEO68381.1 - 1.3e-06 27.8 0.0 2.1e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glyco_transf_36 PF06165.6 AEO68382.1 - 3e-20 72.1 0.0 6.2e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 36 GT36_AF PF06205.6 AEO68382.1 - 6.9e-08 32.1 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase 36 associated family DUF608 PF04685.8 AEO68382.1 - 0.0029 16.3 0.3 0.005 15.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Bac_rhamnosid PF05592.6 AEO68382.1 - 0.025 12.7 0.0 0.043 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase Abhydrolase_6 PF12697.2 AEO68384.1 - 4.9e-20 72.3 0.3 6.3e-20 72.0 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO68384.1 - 3.3e-09 36.6 0.0 4.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 AEO68384.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein HET PF06985.6 AEO68385.1 - 1.3e-23 83.7 0.0 2.9e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) YL1_C PF08265.6 AEO68385.1 - 0.078 12.5 0.4 0.17 11.4 0.3 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain TPR_1 PF00515.23 AEO68385.1 - 0.099 12.2 2.0 0.73 9.5 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 AEO68385.1 - 0.11 12.3 0.3 13 5.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 AEO68385.1 - 0.12 12.3 2.0 1.5 8.9 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 AEO68385.1 - 0.5 10.0 6.2 1.6 8.4 0.0 3.2 3 1 0 3 3 3 0 TPR repeat TPR_12 PF13424.1 AEO68385.1 - 1.5 8.8 13.9 0.16 11.9 1.2 3.8 3 1 2 5 5 5 0 Tetratricopeptide repeat FAD_binding_3 PF01494.14 AEO68386.1 - 8.8e-16 57.8 0.4 5.2e-14 52.0 0.3 2.6 2 1 0 2 2 2 2 FAD binding domain CBM_1 PF00734.13 AEO68387.1 - 5.1e-14 51.6 10.3 5.1e-14 51.6 7.1 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Lipase_GDSL PF00657.17 AEO68387.1 - 2e-12 47.4 0.4 2.8e-12 46.9 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MSP1_C PF07462.6 AEO68387.1 - 1.1 7.6 4.5 1.6 7.0 3.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RGS PF00615.14 AEO68388.1 - 3.9e-07 30.1 0.0 9.3e-06 25.7 0.0 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain Skp1 PF01466.14 AEO68389.1 - 1.5e-27 95.4 0.3 2.5e-27 94.7 0.2 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 AEO68389.1 - 1.1e-05 25.4 0.0 2.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain MFS_1 PF07690.11 AEO68390.1 - 2.6e-33 115.1 38.5 3.8e-33 114.6 26.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SET PF00856.23 AEO68391.1 - 0.048 13.9 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 SET domain UDPGT PF00201.13 AEO68393.1 - 8.8e-08 31.1 0.0 1.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 AEO68393.1 - 0.00012 21.9 0.3 0.00021 21.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Strep_67kDa_ant PF06100.6 AEO68393.1 - 0.049 11.9 0.0 0.069 11.4 0.0 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Polysacc_deac_1 PF01522.16 AEO68394.1 - 3.5e-30 104.1 0.0 4.8e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 AEO68394.1 - 2.5e-06 26.6 0.0 5.2e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 Glyco_transf_34 PF05637.7 AEO68395.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.4 1 1 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Beta-lactamase PF00144.19 AEO68399.1 - 2.6e-35 122.0 3.1 4.2e-35 121.3 2.2 1.2 1 0 0 1 1 1 1 Beta-lactamase NmrA PF05368.8 AEO68400.1 - 4.7e-32 111.0 0.0 5.7e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO68400.1 - 1.8e-12 47.6 0.0 2.6e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO68400.1 - 0.0053 16.2 0.0 0.42 9.9 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family CABS1 PF15367.1 AEO68400.1 - 0.043 12.6 0.0 0.056 12.3 0.0 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 Snf7 PF03357.16 AEO68401.1 - 7.8e-43 145.8 11.9 9.5e-43 145.5 8.2 1.0 1 0 0 1 1 1 1 Snf7 DUF3508 PF12018.3 AEO68401.1 - 0.003 16.6 3.7 0.0049 15.8 2.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3508) Prefoldin_2 PF01920.15 AEO68401.1 - 0.0084 15.8 9.5 0.31 10.8 0.0 3.7 2 1 1 3 3 3 1 Prefoldin subunit DUF4201 PF13870.1 AEO68401.1 - 0.011 15.1 7.9 0.016 14.6 5.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) TBPIP PF07106.8 AEO68401.1 - 0.019 14.4 11.7 1.3 8.5 2.0 3.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Reo_sigmaC PF04582.7 AEO68401.1 - 0.023 13.9 4.4 0.27 10.3 0.4 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein RapA_C PF12137.3 AEO68401.1 - 0.025 13.4 5.2 0.034 12.9 3.6 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal AAA_13 PF13166.1 AEO68401.1 - 0.027 12.9 4.0 0.043 12.2 2.8 1.4 1 0 0 1 1 1 0 AAA domain OmpH PF03938.9 AEO68401.1 - 0.042 13.7 16.6 0.022 14.6 7.7 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FlxA PF14282.1 AEO68401.1 - 0.057 13.3 12.0 0.029 14.2 6.7 1.7 1 1 1 2 2 2 0 FlxA-like protein DUF150 PF02576.12 AEO68401.1 - 0.1 12.1 1.1 0.23 11.0 0.7 1.7 1 1 0 1 1 1 0 Uncharacterised BCR, YhbC family COG0779 NPV_P10 PF05531.7 AEO68401.1 - 0.11 12.8 6.4 8.1 6.7 0.0 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 AEO68401.1 - 0.14 12.2 13.6 1.4 8.9 2.2 2.9 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.4 AEO68401.1 - 0.21 11.7 10.0 0.22 11.7 1.7 2.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NuA4 PF09340.5 AEO68401.1 - 0.21 11.2 1.1 0.49 10.0 0.8 1.7 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 DUF342 PF03961.8 AEO68401.1 - 0.24 9.7 8.6 0.43 8.9 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 AEO68401.1 - 0.25 10.9 12.0 1.9 8.1 6.9 2.2 1 1 2 3 3 3 0 Mnd1 family DUF4140 PF13600.1 AEO68401.1 - 0.27 11.7 12.1 0.38 11.2 0.0 3.9 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF2205 PF10224.4 AEO68401.1 - 0.38 10.3 6.9 0.27 10.8 1.2 2.9 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) FliD_C PF07195.7 AEO68401.1 - 0.46 9.7 0.0 0.46 9.7 0.0 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus IncA PF04156.9 AEO68401.1 - 0.53 9.8 11.9 1.5 8.4 2.6 2.5 1 1 1 2 2 2 0 IncA protein DUF4337 PF14235.1 AEO68401.1 - 2 8.2 9.4 0.45 10.3 3.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF972 PF06156.8 AEO68401.1 - 4.3 7.7 9.7 17 5.7 0.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Mod_r PF07200.8 AEO68401.1 - 4.5 7.1 11.9 9.3 6.1 7.3 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein COG2 PF06148.6 AEO68401.1 - 4.7 7.0 10.5 3.7 7.4 3.8 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.3 AEO68401.1 - 5.3 6.9 13.5 2 8.2 3.0 3.5 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 AEO68401.1 - 5.5 5.9 12.1 1.3 8.0 6.1 1.6 1 1 1 2 2 2 0 Autophagy protein Apg6 FlaC_arch PF05377.6 AEO68401.1 - 8.9 6.3 7.2 8.5 6.3 0.0 3.4 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) WD40 PF00400.27 AEO68402.1 - 8.3e-35 117.4 15.1 6.2e-06 25.8 0.2 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 AEO68402.1 - 1.4e-13 50.3 4.6 3.6e-13 48.9 1.5 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 AEO68402.1 - 1.4e-07 30.9 2.2 1.5e-07 30.8 0.1 2.0 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 AEO68402.1 - 7.2e-07 27.7 1.1 0.0026 15.9 0.0 2.6 3 0 0 3 3 3 2 Nucleoporin Nup120/160 MgtE_N PF03448.12 AEO68402.1 - 0.09 13.1 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain Seadorna_VP6 PF07407.6 AEO68402.1 - 0.12 11.1 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein Nucleoporin_N PF08801.6 AEO68402.1 - 0.13 11.0 1.7 0.38 9.4 0.2 2.5 2 2 1 3 3 3 0 Nup133 N terminal like PH_10 PF15411.1 AEO68403.1 - 4e-46 155.9 0.2 7.4e-46 155.1 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 AEO68403.1 - 6.8e-33 112.5 0.0 1.3e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 AEO68403.1 - 1.5e-32 112.8 0.0 2.6e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 AEO68403.1 - 9.5e-11 41.2 0.0 1.9e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 AEO68403.1 - 0.054 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 PH domain FIVAR PF07554.8 AEO68403.1 - 0.9 9.8 3.6 1.8 8.9 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised Sugar-binding Domain FAD-oxidase_C PF02913.14 AEO68407.1 - 0.003 16.9 0.0 0.78 9.0 0.0 2.1 2 0 0 2 2 2 2 FAD linked oxidases, C-terminal domain DUF2029 PF09594.5 AEO68408.1 - 0.0011 18.4 0.2 0.0011 18.4 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2029) Mid2 PF04478.7 AEO68408.1 - 0.003 17.0 0.1 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 AEO68408.1 - 0.0053 16.0 0.1 0.0053 16.0 0.1 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain SAPS PF04499.10 AEO68409.1 - 1.2e-193 644.0 0.0 2.5e-193 643.0 0.0 1.5 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Acyl-CoA_dh_2 PF08028.6 AEO68410.1 - 8.9e-17 61.5 0.1 8.9e-17 61.5 0.1 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 AEO68410.1 - 2.9e-06 27.8 0.7 4.7e-06 27.1 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 AEO68410.1 - 0.00065 19.8 1.1 0.0035 17.4 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2190 PF09956.4 AEO68410.1 - 0.048 13.4 0.0 0.18 11.5 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) fn3 PF00041.16 AEO68411.1 - 1.7e-12 47.2 0.0 4.3e-08 33.1 0.0 3.4 3 0 0 3 3 3 2 Fibronectin type III domain Lipase_GDSL_2 PF13472.1 AEO68411.1 - 2.4e-09 37.5 4.2 7.7e-09 35.9 2.9 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO68411.1 - 4.8e-05 23.3 0.0 0.00027 20.8 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 AEO68411.1 - 0.0011 18.8 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family adh_short PF00106.20 AEO68412.1 - 6.5e-29 100.9 0.2 9.2e-29 100.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO68412.1 - 5.5e-26 91.8 0.0 6.8e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO68412.1 - 4.4e-15 55.8 0.1 6.2e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO68412.1 - 0.00011 22.2 0.6 0.00015 21.7 0.4 1.4 1 1 0 1 1 1 1 NADH(P)-binding DUF1372 PF07116.6 AEO68412.1 - 0.0071 16.2 0.3 0.014 15.3 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1372) ADH_zinc_N PF00107.21 AEO68412.1 - 0.0074 15.8 2.4 1.5 8.3 1.7 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 AEO68412.1 - 0.025 14.0 0.1 0.032 13.6 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 AEO68412.1 - 0.071 12.1 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lyase_aromatic PF00221.14 AEO68413.1 - 9e-157 522.2 9.0 1.2e-156 521.8 6.2 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase adh_short PF00106.20 AEO68414.1 - 4.8e-23 81.9 0.2 6.7e-23 81.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO68414.1 - 3.1e-10 40.2 0.0 3.8e-10 39.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO68414.1 - 2.1e-09 37.3 0.2 2.9e-09 36.8 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO68414.1 - 2e-07 30.6 0.0 2.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO68414.1 - 0.00065 19.7 0.2 0.00075 19.5 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 AEO68414.1 - 0.0089 15.8 0.2 0.021 14.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.14 AEO68414.1 - 0.0098 14.6 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 AEO68414.1 - 0.079 11.9 0.1 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NmrA PF05368.8 AEO68414.1 - 0.087 12.0 0.2 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Thioredoxin PF00085.15 AEO68414.1 - 0.091 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin EF-hand_1 PF00036.27 AEO68415.1 - 1.1e-36 121.2 10.3 5.1e-09 34.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 AEO68415.1 - 2.3e-33 114.1 9.0 2.5e-16 59.5 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AEO68415.1 - 2.7e-29 98.3 8.6 2.4e-08 33.1 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 AEO68415.1 - 5e-28 96.4 8.6 2.7e-13 49.3 0.4 3.6 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 AEO68415.1 - 5.6e-28 95.0 11.1 7.3e-08 31.4 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 AEO68415.1 - 8.4e-16 57.6 0.3 3.9e-08 33.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 AEO68415.1 - 2.5e-12 46.4 3.1 1.8e-05 24.4 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 AEO68415.1 - 8.5e-07 28.9 0.2 0.011 15.7 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 AEO68415.1 - 7.5e-06 25.7 0.7 0.16 11.7 0.1 2.9 1 1 2 3 3 3 2 Tellurite resistance protein TerB EFhand_Ca_insen PF08726.5 AEO68415.1 - 0.00019 21.3 0.3 0.0074 16.2 0.0 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 AEO68415.1 - 0.0069 15.9 0.0 3.2 7.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_10 PF14788.1 AEO68415.1 - 0.023 14.3 2.6 0.34 10.6 0.1 2.9 2 1 1 3 3 3 0 EF hand Adenine_glyco PF03352.8 AEO68415.1 - 0.038 13.5 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 Methyladenine glycosylase Toprim_2 PF13155.1 AEO68415.1 - 0.05 13.9 1.3 0.9 9.8 0.2 2.2 1 1 1 2 2 2 0 Toprim-like Caleosin PF05042.8 AEO68415.1 - 0.087 12.3 0.2 23 4.5 0.0 3.0 1 1 3 4 4 4 0 Caleosin related protein VCBS PF13517.1 AEO68415.1 - 0.51 10.7 2.8 2 8.8 0.1 2.3 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF4546 PF15079.1 AEO68415.1 - 0.87 8.6 4.9 0.16 11.0 0.2 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4546) GCFC PF07842.7 AEO68416.1 - 4e-79 265.8 4.4 4e-79 265.8 3.0 1.8 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 AEO68416.1 - 1.4e-15 57.2 12.6 1.4e-15 57.2 8.8 3.2 4 0 0 4 4 4 1 Tuftelin interacting protein N terminal G-patch PF01585.18 AEO68416.1 - 1.1e-13 50.7 2.6 1.1e-13 50.7 1.8 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 AEO68416.1 - 3.1e-07 30.1 1.1 3.1e-07 30.1 0.8 3.0 3 0 0 3 3 3 1 DExH-box splicing factor binding site FUSC PF04632.7 AEO68416.1 - 0.048 12.0 2.4 0.096 11.1 1.6 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Epimerase PF01370.16 AEO68417.1 - 5.9e-13 48.7 0.4 2.2e-12 46.9 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO68417.1 - 3.5e-12 46.6 2.9 2.4e-11 43.9 2.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 AEO68417.1 - 4.4e-10 38.7 0.0 6.4e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 AEO68417.1 - 2.4e-05 23.3 0.0 3.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 AEO68417.1 - 3.4e-05 23.2 1.4 0.00017 20.8 0.9 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 AEO68417.1 - 0.00012 21.1 0.0 0.017 14.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Auts2 PF15336.1 AEO68417.1 - 0.0056 16.7 0.6 0.0082 16.1 0.4 1.2 1 0 0 1 1 1 1 Autism susceptibility gene 2 protein Methyltransf_23 PF13489.1 AEO68418.1 - 5.4e-22 78.2 0.1 8.9e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO68418.1 - 7.6e-13 48.7 0.0 1.7e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO68418.1 - 3.3e-10 40.3 0.0 7.6e-09 35.9 0.0 3.0 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO68418.1 - 1.6e-09 37.5 0.0 8.7e-09 35.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO68418.1 - 6e-09 36.4 0.1 4.7e-08 33.5 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO68418.1 - 8.4e-06 25.0 0.0 0.00019 20.6 0.0 2.3 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 AEO68418.1 - 3.1e-05 24.2 0.0 0.0001 22.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 AEO68418.1 - 0.0019 17.4 0.0 0.017 14.3 0.0 2.0 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_26 PF13659.1 AEO68418.1 - 0.0023 17.9 0.0 0.088 12.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 AEO68418.1 - 0.0067 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 AEO68418.1 - 0.0087 15.1 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 AEO68418.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 AEO68418.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 AEO68418.1 - 0.062 13.2 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase PCMT PF01135.14 AEO68418.1 - 0.095 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.7 AEO68418.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF938) CMAS PF02353.15 AEO68418.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase GST_C PF00043.20 AEO68422.1 - 2.9e-12 46.4 0.0 4.3e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AEO68422.1 - 1.7e-10 40.9 0.0 3.3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO68422.1 - 3.2e-10 39.7 0.1 8.7e-10 38.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AEO68422.1 - 1.1e-06 29.0 0.0 1.9e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 AEO68422.1 - 2.9e-06 27.3 0.0 4.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO68422.1 - 0.00084 19.2 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Clathrin PF00637.15 AEO68423.1 - 1.2e-19 70.2 0.4 8.5e-19 67.5 0.1 2.2 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 AEO68423.1 - 8.8e-06 25.4 3.1 0.013 15.3 1.5 3.8 3 1 0 3 3 3 2 WD domain, G-beta repeat Vps39_1 PF10366.4 AEO68423.1 - 0.0044 17.0 0.1 0.015 15.3 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 zf-RING_2 PF13639.1 AEO68423.1 - 0.11 12.3 5.8 0.46 10.3 4.0 2.1 1 1 0 1 1 1 0 Ring finger domain BUD22 PF09073.5 AEO68423.1 - 1 8.3 10.8 0.16 10.9 4.6 1.7 2 0 0 2 2 2 0 BUD22 RXT2_N PF08595.6 AEO68423.1 - 1.9 8.2 6.2 4.5 7.0 4.3 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.7 AEO68423.1 - 3.2 5.5 17.3 5.3 4.8 12.0 1.2 1 0 0 1 1 1 0 Nop14-like family FGF-BP1 PF06473.7 AEO68423.1 - 4.2 6.9 7.3 0.18 11.3 0.1 2.2 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) zf-RING_5 PF14634.1 AEO68423.1 - 6.2 6.6 6.5 0.22 11.2 0.3 1.7 2 0 0 2 2 1 0 zinc-RING finger domain PPP4R2 PF09184.6 AEO68423.1 - 6.7 6.1 18.8 13 5.1 13.0 1.4 1 0 0 1 1 1 0 PPP4R2 VID27 PF08553.5 AEO68423.1 - 6.8 4.7 7.5 11 4.0 5.2 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Apc1 PF12859.2 AEO68424.1 - 9.4e-26 90.0 0.1 2.3e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 AEO68424.1 - 3.5e-11 42.6 1.3 0.0022 18.1 0.0 4.9 4 0 0 4 4 4 3 Proteasome/cyclosome repeat Pkinase PF00069.20 AEO68426.1 - 1.8e-25 89.5 0.0 1.1e-24 87.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO68426.1 - 2.8e-11 43.0 0.0 7.6e-11 41.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO68426.1 - 0.026 13.5 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PBP_GOBP PF01395.17 AEO68426.1 - 0.028 14.0 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 PBP/GOBP family APH PF01636.18 AEO68426.1 - 0.067 12.9 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1824 PF08854.5 AEO68426.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) eIF3_N PF09440.5 AEO68427.1 - 3.3e-51 172.9 6.3 6.7e-51 171.9 3.8 2.0 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 AEO68427.1 - 6.7e-16 58.5 1.0 1.5e-15 57.3 0.1 2.1 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 AEO68427.1 - 0.00065 19.4 0.1 0.0022 17.7 0.1 1.9 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 RPN7 PF10602.4 AEO68427.1 - 0.0048 16.2 0.1 0.0084 15.5 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 HTH_AsnC-type PF13404.1 AEO68427.1 - 0.0093 15.4 0.4 0.036 13.6 0.0 2.1 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain TPR_12 PF13424.1 AEO68427.1 - 0.035 14.0 0.2 0.3 11.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO68427.1 - 0.1 12.2 0.2 0.33 10.6 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat HTH_24 PF13412.1 AEO68427.1 - 0.16 11.3 0.7 0.65 9.4 0.0 2.4 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Img2 PF05046.9 AEO68428.1 - 6.7e-14 51.8 0.3 3e-13 49.7 0.2 1.9 1 1 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Mito_fiss_reg PF05308.6 AEO68428.1 - 1.1 8.5 8.5 2 7.7 5.9 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator ARID PF01388.16 AEO68429.1 - 3.7e-17 61.9 0.0 8.3e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain CDK5_activator PF03261.10 AEO68429.1 - 1.4 8.2 5.9 3.1 7.0 4.1 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein U3_assoc_6 PF08640.6 AEO68431.1 - 7.8e-25 86.4 0.1 1.7e-24 85.3 0.0 1.6 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 AEO68431.1 - 0.0096 16.4 0.6 0.0096 16.4 0.4 5.0 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 AEO68431.1 - 0.019 14.5 0.3 0.058 13.0 0.2 1.9 1 0 0 1 1 1 0 TPR repeat NRDE-2 PF08424.5 AEO68431.1 - 0.027 13.3 0.0 0.18 10.6 0.0 2.1 1 1 1 2 2 2 0 NRDE-2, necessary for RNA interference Frag1 PF10277.4 AEO68432.1 - 1.2e-41 142.6 8.9 1.2e-41 142.6 6.1 2.5 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 AEO68432.1 - 0.00058 19.8 0.0 0.0012 18.8 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ADH_N PF08240.7 AEO68433.1 - 1.2e-05 25.0 0.0 3.2e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain rve PF00665.21 AEO68437.1 - 0.00057 19.9 0.0 0.00065 19.8 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Pkinase PF00069.20 AEO68438.1 - 6.7e-11 41.8 0.1 1.6e-07 30.7 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO68438.1 - 3.7e-06 26.1 0.1 0.002 17.2 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 AEO68438.1 - 0.0024 17.6 0.1 0.01 15.5 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Cellulase PF00150.13 AEO68439.1 - 3.6e-18 65.7 0.1 1.2e-17 63.9 0.1 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mpv17_PMP22 PF04117.7 AEO68439.1 - 0.083 12.5 0.1 0.46 10.1 0.0 2.2 2 0 0 2 2 2 0 Mpv17 / PMP22 family p450 PF00067.17 AEO68440.1 - 5e-61 206.6 0.0 6.8e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3649 PF12365.3 AEO68440.1 - 0.23 11.0 2.6 0.6 9.6 1.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) zf-CCCH PF00642.19 AEO68441.1 - 3.4e-07 29.7 4.2 6.7e-07 28.8 2.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleoporin_FG PF13634.1 AEO68441.1 - 0.022 15.0 105.4 37 4.5 21.3 5.0 2 1 1 3 3 3 0 Nucleoporin FG repeat region CUE PF02845.11 AEO68442.1 - 3.4e-11 42.4 0.3 7.5e-11 41.3 0.1 1.7 2 0 0 2 2 2 1 CUE domain Ribosomal_S10 PF00338.17 AEO68443.1 - 4.3e-29 100.2 0.5 5.1e-29 99.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L17 PF01196.14 AEO68443.1 - 0.13 12.8 1.0 0.19 12.3 0.7 1.3 1 1 0 1 1 1 0 Ribosomal protein L17 TauD PF02668.11 AEO68444.1 - 9.1e-50 169.7 0.1 1.4e-49 169.1 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 AEO68444.1 - 0.00013 20.9 0.0 0.00022 20.2 0.0 1.2 1 0 0 1 1 1 1 CsiD 2OG-FeII_Oxy_3 PF13640.1 AEO68444.1 - 0.031 14.7 0.0 0.097 13.1 0.0 1.9 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF971 PF06155.7 AEO68444.1 - 0.073 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF971) DUF2823 PF11034.3 AEO68445.1 - 0.028 14.5 2.1 0.04 14.0 1.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2823) Ribosomal_L19e PF01280.15 AEO68445.1 - 0.094 12.4 5.5 0.1 12.3 3.8 1.1 1 0 0 1 1 1 0 Ribosomal protein L19e IATP PF04568.7 AEO68445.1 - 5.8 6.9 10.0 0.5 10.4 2.0 2.0 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP zf-C2H2_4 PF13894.1 AEO68447.1 - 2.6e-05 24.2 8.7 0.0078 16.4 0.3 3.4 2 1 1 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO68447.1 - 0.002 18.3 13.0 0.16 12.3 0.6 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 AEO68447.1 - 0.2 11.9 1.3 29 5.1 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain FAD_binding_3 PF01494.14 AEO68448.1 - 1.7e-47 162.1 0.0 2.1e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Metallophos PF00149.23 AEO68449.1 - 4.5e-39 133.9 1.2 7e-39 133.2 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 AEO68449.1 - 2.3e-12 46.7 0.1 6.3e-12 45.3 0.1 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 AEO68449.1 - 4.1e-10 38.8 0.9 1.6e-09 36.8 0.5 1.8 2 0 0 2 2 2 1 PhoD-like phosphatase fn3 PF00041.16 AEO68449.1 - 0.00087 19.3 0.1 0.0022 18.0 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Metallophos_2 PF12850.2 AEO68449.1 - 0.0047 16.7 0.0 0.027 14.2 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4233 PF14017.1 AEO68450.1 - 5.8 6.8 15.9 1.8 8.5 1.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4233) Asp PF00026.18 AEO68451.1 - 2.3e-57 194.6 0.0 2.7e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO68451.1 - 1.8e-05 24.7 0.2 0.0006 19.7 0.0 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 AEO68451.1 - 0.0053 16.3 0.1 0.094 12.2 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal HET PF06985.6 AEO68452.1 - 5.6e-06 26.5 0.0 0.0038 17.3 0.0 2.7 2 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) RicinB_lectin_2 PF14200.1 AEO68453.1 - 0.00052 20.3 0.1 0.41 11.0 0.0 2.2 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 AEO68453.1 - 0.0064 16.5 0.0 0.01 15.8 0.0 1.3 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain adh_short PF00106.20 AEO68454.1 - 6.9e-17 61.8 0.0 8.9e-16 58.2 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO68454.1 - 1e-10 41.5 0.1 2.4e-10 40.3 0.0 1.5 2 0 0 2 2 2 1 KR domain Fungal_trans PF04082.13 AEO68455.1 - 1.7e-16 59.8 0.1 3.4e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO68455.1 - 1.8e-05 24.5 12.0 1.8e-05 24.5 8.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 AEO68456.1 - 7.7e-08 31.9 0.5 1.6e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO68456.1 - 1.5e-07 31.1 0.1 4.6e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AEO68456.1 - 0.0039 18.0 0.0 0.012 16.5 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 AEO68456.1 - 0.062 12.2 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase Band_7 PF01145.20 AEO68458.1 - 3.1e-12 46.7 0.9 3.1e-12 46.7 0.6 3.6 2 2 0 2 2 2 1 SPFH domain / Band 7 family adh_short PF00106.20 AEO68459.1 - 1.4e-19 70.5 0.4 1.8e-19 70.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO68459.1 - 2.3e-08 34.1 0.0 3.1e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO68459.1 - 5.1e-07 29.5 0.3 1.2e-06 28.3 0.2 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO68459.1 - 5.8e-06 26.4 0.1 1.2e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 AEO68459.1 - 0.00095 18.6 0.4 0.0052 16.2 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 AEO68459.1 - 0.003 16.6 0.4 0.0052 15.8 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 AEO68459.1 - 0.0044 17.1 0.0 0.0064 16.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 AEO68459.1 - 0.05 13.0 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 AEO68459.1 - 0.088 12.6 0.1 0.2 11.4 0.0 1.6 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Eno-Rase_NADH_b PF12242.3 AEO68459.1 - 0.11 12.2 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase BRO1 PF03097.13 AEO68460.1 - 2.7e-113 378.5 0.5 4.5e-113 377.8 0.4 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 AEO68460.1 - 2.4e-77 259.8 7.5 2.6e-77 259.7 4.2 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV K-box PF01486.12 AEO68460.1 - 0.016 14.9 1.3 0.06 13.1 0.0 2.5 2 0 0 2 2 2 0 K-box region TMF_DNA_bd PF12329.3 AEO68460.1 - 0.071 12.9 3.5 0.34 10.7 2.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 AEO68460.1 - 0.38 10.3 8.2 1.9 8.0 5.7 2.2 1 0 0 1 1 1 0 IncA protein DUF605 PF04652.11 AEO68460.1 - 1.3 8.3 18.3 2 7.7 12.7 1.3 1 0 0 1 1 1 0 Vta1 like p450 PF00067.17 AEO68461.1 - 1.3e-53 182.1 0.0 7.6e-53 179.6 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Stirrup PF09061.1 AEO68461.1 - 0.075 12.9 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Stirrup ADH_zinc_N PF00107.21 AEO68462.1 - 4.8e-23 81.1 0.4 7.9e-23 80.4 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO68462.1 - 5.7e-21 74.3 0.0 9.2e-21 73.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AEO68462.1 - 8.6e-05 23.4 0.0 0.00019 22.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 AEO68462.1 - 0.011 15.2 0.4 0.025 14.1 0.3 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_11 PF08241.7 AEO68462.1 - 0.025 15.0 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 AEO68462.1 - 0.028 13.8 0.1 0.045 13.1 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 AEO68462.1 - 0.041 14.2 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 AEO68462.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF2961 PF11175.3 AEO68463.1 - 5.6e-84 281.1 3.6 7.3e-84 280.7 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2961) Zn_clus PF00172.13 AEO68464.1 - 1.1e-09 38.0 10.1 2.2e-09 37.0 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO68464.1 - 3.6e-07 29.3 0.0 5.9e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_32N PF00251.15 AEO68465.1 - 5.1e-44 150.8 0.0 2.3e-29 102.7 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 AEO68465.1 - 7.4e-11 42.2 0.0 1.4e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.1 AEO68465.1 - 8.5e-06 25.2 0.1 1.7e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 AEO68465.1 - 0.1 12.4 0.1 0.1 12.4 0.1 3.2 3 0 0 3 3 3 0 BNR/Asp-box repeat Sugar_tr PF00083.19 AEO68466.1 - 1.1e-71 241.7 19.1 1.5e-71 241.3 13.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO68466.1 - 3.6e-19 68.6 28.0 7.4e-19 67.6 18.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO68466.1 - 9.4e-06 24.0 0.6 9.4e-06 24.0 0.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) VIT1 PF01988.14 AEO68467.1 - 4.6e-69 232.1 2.9 5.3e-69 231.9 2.0 1.0 1 0 0 1 1 1 1 VIT family Periviscerokin PF08259.6 AEO68467.1 - 6.8 7.1 6.4 9.4 6.6 0.6 3.1 2 0 0 2 2 2 0 Periviscerokinin family Fringe PF02434.11 AEO68470.1 - 3.1e-06 26.5 0.0 6.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.7 AEO68470.1 - 2e-05 23.9 0.0 9e-05 21.8 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF604 DUF500 PF04366.7 AEO68471.1 - 3.1e-48 162.3 0.1 6e-48 161.4 0.0 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF500) Cu-oxidase_2 PF07731.9 AEO68473.1 - 2.6e-38 130.6 5.7 1.5e-35 121.7 0.1 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 AEO68473.1 - 5.8e-35 120.5 0.1 1.1e-34 119.5 0.1 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 AEO68473.1 - 1.3e-34 118.4 1.2 1.3e-34 118.4 0.8 2.6 4 0 0 4 4 4 1 Multicopper oxidase Condensation PF00668.15 AEO68475.1 - 2.2e-91 305.8 0.0 2.4e-33 115.2 0.0 3.9 3 1 0 3 3 3 3 Condensation domain AMP-binding PF00501.23 AEO68475.1 - 9.5e-41 139.5 0.0 1.6e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 AEO68475.1 - 2.3e-23 82.2 0.2 2.1e-08 34.3 0.0 5.1 5 0 0 5 5 5 3 Phosphopantetheine attachment site adh_short PF00106.20 AEO68476.1 - 8.7e-06 25.7 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO68476.1 - 6.1e-05 22.7 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Metallophos PF00149.23 AEO68477.1 - 0.006 16.0 1.5 0.018 14.4 0.1 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase CLASP_N PF12348.3 AEO68478.1 - 7.4e-09 35.2 0.2 1e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 CLASP N terminal HEAT_2 PF13646.1 AEO68478.1 - 3.6e-07 30.3 7.0 0.033 14.4 0.8 4.7 2 2 0 3 3 3 2 HEAT repeats HEAT PF02985.17 AEO68478.1 - 1.1e-06 28.2 5.4 0.84 9.8 0.1 6.4 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.15 AEO68478.1 - 7.8e-06 24.4 2.0 0.0095 14.3 0.2 3.0 2 2 1 3 3 3 2 Adaptin N terminal region APG6 PF04111.7 AEO68478.1 - 0.0028 16.7 10.3 0.0068 15.4 7.1 1.5 1 0 0 1 1 1 1 Autophagy protein Apg6 TAN PF11640.3 AEO68478.1 - 0.038 13.7 0.7 0.49 10.1 0.0 2.9 3 1 0 3 3 3 0 Telomere-length maintenance and DNA damage repair Cnd1 PF12717.2 AEO68478.1 - 0.045 13.6 2.1 0.52 10.1 0.1 2.5 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF2514 PF10721.4 AEO68478.1 - 0.19 11.4 14.1 0.014 15.0 5.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2514) T2SF PF00482.18 AEO68478.1 - 0.21 11.5 1.9 3.3 7.6 0.1 3.5 2 2 1 3 3 3 0 Type II secretion system (T2SS), protein F NYD-SP28_assoc PF14775.1 AEO68478.1 - 1.6 8.5 6.0 0.5 10.0 0.8 2.6 2 1 0 2 2 2 0 Sperm tail C-terminal domain DUF972 PF06156.8 AEO68478.1 - 4.2 7.7 7.3 53 4.2 0.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) WD40 PF00400.27 AEO68479.1 - 1.7e-74 243.2 19.6 1.6e-11 43.6 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 AEO68479.1 - 2.2e-10 39.3 2.3 9.4e-05 20.7 0.1 4.3 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AEO68479.1 - 0.0018 17.0 0.0 0.25 10.0 0.0 3.2 1 1 2 3 3 3 1 Nup133 N terminal like bZIP_1 PF00170.16 AEO68479.1 - 0.12 12.3 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 bZIP transcription factor DUF1162 PF06650.7 AEO68486.1 - 4e-86 288.6 0.0 3.3e-85 285.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 AEO68486.1 - 5.7e-42 141.9 0.1 1.6e-41 140.5 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 AEO68486.1 - 9.1e-06 25.7 0.4 6.4e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 ATG C terminal domain DUF3429 PF11911.3 AEO68487.1 - 8.3e-40 136.0 12.4 1.1e-39 135.6 8.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF1510 PF07423.6 AEO68487.1 - 0.00099 18.5 11.5 0.0013 18.1 8.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF4220 PF13968.1 AEO68487.1 - 0.0037 16.4 0.3 0.0054 15.8 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4220) DUF2881 PF11087.3 AEO68487.1 - 0.044 13.2 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2881) DUF4207 PF13904.1 AEO68487.1 - 0.058 12.7 17.4 0.09 12.1 12.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DUF4337 PF14235.1 AEO68487.1 - 0.81 9.5 8.9 1.9 8.3 6.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Paramyxo_ncap PF00973.14 AEO68487.1 - 7.7 5.0 7.9 11 4.6 5.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RicinB_lectin_2 PF14200.1 AEO68488.1 - 0.051 13.9 0.0 0.092 13.1 0.0 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like FAD_binding_3 PF01494.14 AEO68489.1 - 5.9e-14 51.8 0.0 1.2e-13 50.9 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO68489.1 - 2.3e-12 46.4 0.0 4.5e-08 32.3 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO68489.1 - 0.0011 19.3 0.0 1 9.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 AEO68489.1 - 0.0063 15.2 0.0 0.23 10.0 0.0 2.4 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.1 AEO68489.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 AEO68489.1 - 0.053 12.3 0.0 2.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.1 AEO68489.1 - 0.06 13.1 0.1 1 9.1 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Amino_oxidase PF01593.19 AEO68489.1 - 0.09 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase UPF0150 PF03681.10 AEO68490.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) DUF3201 PF11447.3 AEO68490.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) Zn_clus PF00172.13 AEO68491.1 - 3e-07 30.2 10.6 3e-07 30.2 7.3 2.6 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 AEO68491.1 - 0.035 14.4 2.8 0.035 14.4 2.0 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2797 PF10977.3 AEO68491.1 - 0.35 10.4 2.9 0.62 9.6 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) zf-C2H2_4 PF13894.1 AEO68491.1 - 7.6 7.1 10.7 0.085 13.2 1.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger GFO_IDH_MocA PF01408.17 AEO68492.1 - 3.5e-17 63.0 0.0 5e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 AEO68492.1 - 0.0073 16.7 0.2 0.013 15.8 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain UbiA PF01040.13 AEO68494.1 - 1.3e-23 83.5 36.0 2.5e-23 82.6 24.1 2.0 1 1 0 1 1 1 1 UbiA prenyltransferase family Glyco_transf_90 PF05686.7 AEO68497.1 - 3e-14 52.5 0.0 5.6e-10 38.4 0.0 3.2 3 1 0 3 3 3 2 Glycosyl transferase family 90 CAV_VP3 PF04771.7 AEO68498.1 - 0.17 11.8 1.4 2.7 7.9 0.2 2.2 1 1 1 2 2 2 0 Chicken anaemia virus VP-3 protein Zip PF02535.17 AEO68499.1 - 0.033 13.2 8.7 0.03 13.3 6.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 AEO68499.1 - 0.59 9.4 18.1 0.78 9.0 12.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1777 PF08648.7 AEO68499.1 - 8.5 6.0 14.6 11 5.7 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) TPR_19 PF14559.1 AEO68500.1 - 0.0058 16.9 1.9 0.038 14.3 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 AEO68500.1 - 0.032 14.9 0.8 0.099 13.3 0.6 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO68500.1 - 0.19 12.4 0.1 0.19 12.4 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat CAP_N PF01213.14 AEO68500.1 - 0.26 10.5 4.9 0.29 10.3 0.0 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal TPR_11 PF13414.1 AEO68500.1 - 0.33 10.6 1.5 19 4.9 0.1 2.4 2 0 0 2 2 2 0 TPR repeat APH PF01636.18 AEO68502.1 - 2.7e-21 76.3 1.4 3.5e-21 76.0 0.9 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO68502.1 - 2.9e-05 23.7 0.0 4.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 AEO68502.1 - 0.011 14.9 0.0 0.25 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain EcKinase PF02958.15 AEO68502.1 - 0.03 13.4 0.0 0.12 11.4 0.0 1.8 1 1 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.17 AEO68502.1 - 0.053 12.8 0.0 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 RIO1 family FA_hydroxylase PF04116.8 AEO68503.1 - 5e-18 65.5 11.2 5e-18 65.5 7.8 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily GFO_IDH_MocA_C PF02894.12 AEO68504.1 - 3.5e-17 62.2 0.2 2.7e-16 59.3 0.2 2.2 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 AEO68504.1 - 7.8e-15 55.4 0.0 1.4e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Cys_Met_Meta_PP PF01053.15 AEO68504.1 - 0.083 11.1 0.1 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme ADIP PF11559.3 AEO68505.1 - 0.0051 16.7 2.8 0.0057 16.5 2.0 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Lzipper-MIP1 PF14389.1 AEO68505.1 - 0.0077 16.3 2.6 0.0096 16.0 1.8 1.1 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 SKIP_SNW PF02731.10 AEO68505.1 - 0.025 14.0 5.0 0.029 13.8 3.4 1.1 1 0 0 1 1 1 0 SKIP/SNW domain IFP_35_N PF07334.8 AEO68505.1 - 0.03 14.2 1.9 0.039 13.9 1.3 1.2 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus OmpH PF03938.9 AEO68505.1 - 0.043 13.7 4.5 0.042 13.7 3.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.7 AEO68505.1 - 0.075 12.7 1.3 0.089 12.5 0.9 1.1 1 0 0 1 1 1 0 Laminin Domain II AAA_13 PF13166.1 AEO68505.1 - 0.075 11.4 1.7 0.08 11.3 1.1 1.0 1 0 0 1 1 1 0 AAA domain HlyD PF00529.15 AEO68505.1 - 0.077 12.2 5.7 0.09 12.0 4.0 1.0 1 0 0 1 1 1 0 HlyD family secretion protein Syntaxin-6_N PF09177.6 AEO68505.1 - 0.11 12.8 2.9 0.15 12.4 2.0 1.1 1 0 0 1 1 1 0 Syntaxin 6, N-terminal RPN7 PF10602.4 AEO68505.1 - 0.25 10.6 2.4 0.2 11.0 0.9 1.4 1 1 0 1 1 1 0 26S proteasome subunit RPN7 Mnd1 PF03962.10 AEO68505.1 - 0.36 10.4 4.2 0.43 10.2 2.9 1.1 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 AEO68505.1 - 0.38 10.3 3.2 0.44 10.1 2.2 1.1 1 0 0 1 1 1 0 IncA protein DUF2570 PF10828.3 AEO68505.1 - 0.56 9.8 3.3 0.7 9.5 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF2514 PF10721.4 AEO68505.1 - 0.71 9.5 8.3 0.79 9.4 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) XhlA PF10779.4 AEO68505.1 - 0.9 9.5 6.4 1.2 9.1 4.4 1.2 1 0 0 1 1 1 0 Haemolysin XhlA APG6 PF04111.7 AEO68505.1 - 1 8.3 4.3 1 8.3 3.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc24 PF08286.6 AEO68505.1 - 1.4 8.5 4.9 1.8 8.2 3.4 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 RNA_pol_3_Rpc31 PF11705.3 AEO68505.1 - 4.1 7.2 7.8 4.1 7.2 5.4 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2968 PF11180.3 AEO68506.1 - 0.0022 17.3 5.9 0.0054 16.1 4.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) DUF2383 PF09537.5 AEO68506.1 - 0.014 15.6 1.9 0.062 13.5 1.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Pilin_PilA PF14245.1 AEO68506.1 - 0.021 15.3 0.0 4.8 7.7 0.0 3.0 2 0 0 2 2 2 0 Type IV pilin PilA XisH PF08814.5 AEO68506.1 - 0.034 14.1 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 XisH protein DUF241 PF03087.9 AEO68506.1 - 0.068 12.6 0.7 0.17 11.3 0.1 1.8 2 0 0 2 2 2 0 Arabidopsis protein of unknown function DUF3610 PF12272.3 AEO68506.1 - 0.069 12.7 1.1 0.11 12.1 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3610) GED PF02212.13 AEO68506.1 - 0.3 11.0 2.7 8.3 6.3 0.4 2.6 2 0 0 2 2 2 0 Dynamin GTPase effector domain MFS_1 PF07690.11 AEO68507.1 - 2.7e-31 108.5 30.6 2.7e-31 108.5 21.2 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 AEO68508.1 - 1.7e-35 122.4 24.1 1.7e-35 122.4 16.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sars6 PF12133.3 AEO68508.1 - 0.056 13.1 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus zf-ribbon_3 PF13248.1 AEO68509.1 - 0.0025 16.9 6.6 0.26 10.5 0.1 2.5 2 0 0 2 2 2 2 zinc-ribbon domain Amb_V_allergen PF03913.8 AEO68509.1 - 0.53 10.0 4.1 6.1 6.6 0.4 2.8 2 0 0 2 2 2 0 Amb V Allergen Herpes_UL49_2 PF04823.7 AEO68509.1 - 0.6 10.1 5.4 1.2 9.1 0.9 2.7 2 0 0 2 2 2 0 Herpesvirus UL49 tegument protein EmrE PF13536.1 AEO68509.1 - 0.84 9.8 6.8 8.3 6.6 0.8 2.7 2 0 0 2 2 2 0 Multidrug resistance efflux transporter DZR PF12773.2 AEO68509.1 - 1.3 8.9 12.4 0.9 9.4 0.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon NOB1_Zn_bind PF08772.6 AEO68509.1 - 3.1 7.7 7.4 29 4.5 2.4 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like TerY-C PF15616.1 AEO68509.1 - 3.3 7.6 8.8 3.8 7.4 1.2 2.2 2 0 0 2 2 2 0 TerY-C metal binding domain adh_short PF00106.20 AEO68511.1 - 3.7e-15 56.2 1.4 5.2e-15 55.7 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO68511.1 - 1.1e-09 38.2 0.2 2.1e-09 37.3 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO68511.1 - 1.3e-08 34.5 0.0 1.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 AEO68511.1 - 4.4e-05 22.6 0.8 0.00018 20.5 0.3 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase 3HCDH_N PF02737.13 AEO68511.1 - 0.00062 19.4 0.1 0.001 18.7 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 AEO68511.1 - 0.017 15.1 2.6 0.041 13.8 1.8 1.9 1 1 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 AEO68511.1 - 0.018 15.1 0.3 0.057 13.5 0.1 1.9 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 AEO68511.1 - 0.054 12.3 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 AEO68511.1 - 0.11 11.5 0.1 0.53 9.3 0.1 2.2 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1479 PF07350.7 AEO68513.1 - 2e-160 533.8 0.0 2.7e-160 533.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Peptidase_M1 PF01433.15 AEO68515.1 - 5.9e-136 453.6 0.2 1.3e-135 452.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 AEO68515.1 - 2.1e-70 237.5 0.0 1.5e-69 234.7 0.0 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 AEO68515.1 - 1.4e-20 73.6 2.3 6.4e-20 71.4 0.1 2.4 1 1 1 2 2 2 1 Peptidase MA superfamily DUF45 PF01863.12 AEO68515.1 - 0.0034 17.1 0.1 0.016 15.0 0.1 2.0 2 1 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.4 AEO68515.1 - 0.026 14.1 0.0 0.077 12.6 0.0 1.8 2 0 0 2 2 2 0 SprT-like family Tcp11 PF05794.8 AEO68516.1 - 1.2e-42 146.1 0.0 1.2e-42 146.1 0.0 1.5 2 0 0 2 2 2 1 T-complex protein 11 DUF647 PF04884.9 AEO68516.1 - 0.16 11.1 3.3 0.34 10.0 2.3 1.5 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis RskA PF10099.4 AEO68517.1 - 0.0032 17.2 0.1 0.056 13.1 0.1 2.2 2 0 0 2 2 2 1 Anti-sigma-K factor rskA NPDC1 PF06809.6 AEO68517.1 - 0.042 12.6 0.3 0.074 11.8 0.2 1.4 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) Fringe PF02434.11 AEO68518.1 - 9.8e-06 24.9 1.6 8.5e-05 21.8 1.1 2.2 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 AEO68518.1 - 0.058 12.9 0.0 0.15 11.6 0.0 1.7 1 1 0 1 1 1 0 Galactosyltransferase Cellulase PF00150.13 AEO68519.1 - 3.2e-53 180.7 1.1 3.8e-53 180.5 0.7 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SAD_SRA PF02182.12 AEO68521.1 - 8.4e-21 73.8 0.0 1.5e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain Sugar_tr PF00083.19 AEO68522.1 - 2.2e-98 329.7 33.2 2.9e-98 329.3 23.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO68522.1 - 3.1e-21 75.4 38.9 6.4e-21 74.4 15.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO68522.1 - 0.0042 15.5 0.6 0.0042 15.5 0.4 3.8 2 2 2 4 4 4 2 MFS/sugar transport protein Alpha-L-AF_C PF06964.7 AEO68523.1 - 1.1e-34 119.7 0.0 1.9e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Sugar_tr PF00083.19 AEO68524.1 - 1.8e-97 326.7 17.5 2e-97 326.6 12.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO68524.1 - 9.5e-28 96.9 30.3 4e-19 68.5 11.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MatC_N PF07158.6 AEO68524.1 - 0.056 13.2 2.5 0.059 13.1 0.6 2.0 2 1 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus Oxysterol_BP PF01237.13 AEO68525.1 - 9.6e-61 205.2 0.0 7.2e-60 202.3 0.0 1.9 1 1 0 1 1 1 1 Oxysterol-binding protein Tyrosinase PF00264.15 AEO68527.1 - 2.4e-49 168.5 0.1 4.1e-49 167.7 0.0 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase DUF897 PF05982.7 AEO68527.1 - 0.18 10.5 0.5 0.31 9.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF897) FAD_binding_2 PF00890.19 AEO68528.1 - 2.5e-93 313.2 0.1 2.9e-93 313.0 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 AEO68528.1 - 3.1e-07 30.3 0.0 1.3e-06 28.2 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 AEO68528.1 - 6.3e-05 22.0 0.1 0.00013 20.9 0.1 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 AEO68528.1 - 6.8e-05 22.0 0.1 0.00018 20.6 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 AEO68528.1 - 7.2e-05 21.9 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AEO68528.1 - 0.00011 22.1 0.0 0.0017 18.2 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AEO68528.1 - 0.00018 20.5 0.7 0.0026 16.7 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AEO68528.1 - 0.00064 18.3 1.9 0.0034 15.9 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 AEO68528.1 - 0.003 17.6 0.0 0.0053 16.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO68528.1 - 0.0077 15.3 0.0 0.018 14.1 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 AEO68528.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 AEO68528.1 - 0.029 13.3 0.2 0.05 12.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.11 AEO68529.1 - 2e-26 92.5 26.8 2e-26 92.5 18.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily AAA_16 PF13191.1 AEO68530.1 - 4.7e-05 23.4 2.1 0.03 14.3 0.1 2.4 2 1 0 2 2 2 2 AAA ATPase domain UvrD-helicase PF00580.16 AEO68530.1 - 0.00043 19.6 0.3 0.00061 19.1 0.2 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 AEO68530.1 - 0.049 13.7 0.0 0.54 10.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 AEO68530.1 - 0.27 11.0 4.4 1.3 8.7 3.0 2.3 1 1 0 1 1 1 0 Part of AAA domain Pro-kuma_activ PF09286.6 AEO68531.1 - 2.6e-18 66.4 0.2 8.8e-11 42.0 0.0 3.0 2 1 1 3 3 3 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 AEO68531.1 - 7.4e-05 22.0 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Asp PF00026.18 AEO68532.1 - 1.5e-58 198.5 0.5 1.8e-58 198.2 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO68532.1 - 7.3e-10 39.0 1.0 1.1e-08 35.2 0.1 3.1 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO68532.1 - 4.1e-05 23.9 0.0 0.42 11.1 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 AEO68532.1 - 5.1e-05 22.8 0.0 0.0011 18.5 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 AEO68532.1 - 0.11 12.2 0.1 1.3 8.8 0.1 2.6 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease 2OG-FeII_Oxy_3 PF13640.1 AEO68533.1 - 0.00083 19.8 0.1 0.003 18.0 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 AEO68533.1 - 0.0017 18.5 0.0 0.043 14.1 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Thioredoxin_6 PF13848.1 AEO68534.1 - 4.1e-15 56.0 0.0 4.8e-12 46.0 0.0 2.0 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 AEO68534.1 - 4.5e-07 29.4 0.0 1.3e-05 24.8 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin Docking PF08990.6 AEO68534.1 - 0.051 12.8 0.4 0.27 10.4 0.1 2.3 2 0 0 2 2 2 0 Erythronolide synthase docking COesterase PF00135.23 AEO68535.1 - 8.4e-94 315.1 0.0 1.2e-93 314.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO68535.1 - 0.003 17.1 0.4 0.011 15.3 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold P21-Arc PF04062.9 AEO68537.1 - 2e-77 258.9 0.0 2.2e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.8 AEO68538.1 - 9.7e-77 258.0 0.0 1.4e-76 257.5 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family MFS_1 PF07690.11 AEO68539.1 - 5.5e-34 117.4 27.9 7.5e-34 116.9 19.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily E1-E2_ATPase PF00122.15 AEO68540.1 - 1.6e-46 158.2 4.1 1.6e-46 158.2 1.5 2.0 1 1 1 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AEO68540.1 - 9.6e-43 145.8 5.2 9.6e-43 145.8 3.6 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AEO68540.1 - 2e-30 106.8 0.0 6.4e-30 105.1 0.0 1.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO68540.1 - 2.7e-15 56.0 0.0 5e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 AEO68540.1 - 2e-13 49.5 0.0 5.3e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 AEO68540.1 - 1.3e-12 48.3 0.1 4.4e-12 46.5 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AEO68540.1 - 0.0054 16.3 0.5 0.01 15.3 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FUR PF01475.14 AEO68540.1 - 0.23 11.3 0.0 0.44 10.4 0.0 1.4 1 0 0 1 1 1 0 Ferric uptake regulator family DUF2207 PF09972.4 AEO68540.1 - 6 5.3 5.3 1.2 7.6 0.0 2.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) OPT PF03169.10 AEO68541.1 - 4.7e-148 494.3 50.8 5.5e-148 494.1 35.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TPR_16 PF13432.1 AEO68541.1 - 0.072 13.7 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2638 PF10937.3 AEO68544.1 - 8.5e-37 126.6 0.6 1e-36 126.3 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) Cyto_heme_lyase PF01265.12 AEO68545.1 - 9.2e-86 287.6 0.3 1.1e-85 287.3 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase TFIIA PF03153.8 AEO68545.1 - 5.4 6.8 12.5 6.7 6.4 8.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IpaD PF06511.6 AEO68545.1 - 6.7 5.6 9.7 9.2 5.1 6.7 1.2 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD DUF647 PF04884.9 AEO68546.1 - 5.4e-100 333.7 1.1 7e-100 333.3 0.7 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis GHMP_kinases_N PF00288.21 AEO68547.1 - 1.9e-10 40.6 4.0 3.6e-10 39.7 1.2 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain MARVEL PF01284.18 AEO68548.1 - 2.1e-06 27.5 8.5 3.3e-06 26.9 5.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain ABC2_membrane_5 PF13346.1 AEO68548.1 - 0.0047 16.2 2.2 0.0065 15.7 1.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein EmrE PF13536.1 AEO68548.1 - 0.19 11.9 7.4 0.37 11.0 5.1 1.6 1 1 0 1 1 1 0 Multidrug resistance efflux transporter ILVD_EDD PF00920.16 AEO68550.1 - 1.3e-157 525.4 1.8 1.5e-157 525.2 1.3 1.0 1 0 0 1 1 1 1 Dehydratase family Cluap1 PF10234.4 AEO68550.1 - 0.17 11.0 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 MFS_1 PF07690.11 AEO68551.1 - 1.2e-27 96.5 29.9 1.2e-27 96.5 20.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO68551.1 - 2.3e-10 39.6 14.5 4.6e-10 38.6 9.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter DUF554 PF04474.7 AEO68551.1 - 0.022 13.8 0.2 0.022 13.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF554) DUF1129 PF06570.6 AEO68551.1 - 0.74 9.0 3.0 0.61 9.3 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Hemerythrin PF01814.18 AEO68552.1 - 7.7e-07 29.3 5.4 1.5e-06 28.4 2.4 2.0 1 1 1 2 2 2 1 Hemerythrin HHE cation binding domain DUF3014 PF11219.3 AEO68552.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3014) Glyco_hydro_43 PF04616.9 AEO68554.1 - 1.6e-36 125.8 3.3 2e-36 125.5 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Nucleos_tra2_C PF07662.8 AEO68555.1 - 8.8e-66 221.3 0.2 8.8e-66 221.3 0.1 2.4 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 AEO68555.1 - 8.5e-21 74.0 2.6 8.5e-21 74.0 1.8 2.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 AEO68555.1 - 1.6 8.6 19.6 0.076 12.9 6.9 3.2 2 1 1 3 3 3 0 Nucleoside recognition PNK3P PF08645.6 AEO68556.1 - 1.3e-58 196.9 0.0 1.9e-58 196.3 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 AEO68556.1 - 1.1e-30 106.3 0.0 8e-30 103.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 AEO68556.1 - 0.002 17.2 0.0 0.021 13.9 0.0 2.2 1 1 1 2 2 2 1 Zeta toxin AAA_22 PF13401.1 AEO68556.1 - 0.0072 16.4 0.0 0.019 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO68556.1 - 0.024 14.9 0.4 9.7 6.5 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 AEO68556.1 - 0.034 14.9 0.1 0.11 13.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AEO68556.1 - 0.041 13.4 0.0 0.12 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.5 AEO68556.1 - 0.048 12.8 0.1 1.6 7.8 0.0 2.2 1 1 1 2 2 2 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 AEO68556.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 AEO68556.1 - 0.12 11.5 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CTV_P13 PF06922.6 AEO68556.1 - 0.16 11.8 0.0 22 4.9 0.0 2.8 3 0 0 3 3 3 0 Citrus tristeza virus P13 protein Sugar_tr PF00083.19 AEO68557.1 - 2e-103 346.3 19.2 4.6e-103 345.2 13.3 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO68557.1 - 1.3e-26 93.2 44.4 6.8e-26 90.8 17.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily 1-cysPrx_C PF10417.4 AEO68558.1 - 0.018 14.6 0.4 0.56 9.8 0.0 2.6 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin adh_short PF00106.20 AEO68559.1 - 6.5e-16 58.6 0.1 2.4e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO68559.1 - 9e-06 25.4 0.2 1.5e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO68559.1 - 5e-05 23.1 0.0 7.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ORC6 PF05460.8 AEO68560.1 - 0.029 13.4 6.1 0.046 12.8 4.2 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Acetyltransf_8 PF13523.1 AEO68561.1 - 4.8e-35 120.6 0.2 7.6e-35 120.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF607 PF04678.8 AEO68562.1 - 8.2e-41 139.9 0.8 8.2e-41 139.9 0.6 2.3 2 1 0 2 2 2 1 Protein of unknown function, DUF607 Vfa1 PF08432.5 AEO68563.1 - 6.8e-58 195.6 19.6 7.6e-58 195.5 13.6 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Ycf1 PF05758.7 AEO68563.1 - 1.7 6.2 16.1 2 6.0 11.2 1.0 1 0 0 1 1 1 0 Ycf1 Atg14 PF10186.4 AEO68563.1 - 2.5 6.9 8.2 3.9 6.3 5.7 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NPR3 PF03666.8 AEO68563.1 - 3.8 5.9 10.3 4.4 5.7 7.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Asp-B-Hydro_N PF05279.6 AEO68563.1 - 3.9 7.2 20.3 4.9 6.9 14.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CDC45 PF02724.9 AEO68563.1 - 6.4 4.6 21.6 7.8 4.3 15.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.1 AEO68563.1 - 6.6 5.6 15.5 8.3 5.2 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sporozoite_P67 PF05642.6 AEO68563.1 - 8.5 4.1 10.9 10 3.8 7.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DSPc PF00782.15 AEO68564.1 - 1.7e-17 63.2 0.0 2e-10 40.3 0.0 2.9 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 AEO68564.1 - 0.05 12.4 0.0 0.063 12.1 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 AEO68564.1 - 0.053 13.7 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 AEO68564.1 - 0.059 12.6 0.0 0.11 11.7 0.0 1.4 1 1 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 AEO68564.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate zf-LSD1 PF06943.7 AEO68564.1 - 0.54 9.9 3.2 2.3 7.8 0.1 2.6 2 0 0 2 2 2 0 LSD1 zinc finger zf-C2H2_4 PF13894.1 AEO68565.1 - 5.4e-06 26.3 18.7 0.026 14.8 0.8 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO68565.1 - 5.2e-05 23.3 22.8 0.016 15.4 0.7 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO68565.1 - 0.0042 17.3 0.2 0.0042 17.3 0.2 4.2 5 0 0 5 5 5 1 Zinc-finger double domain zf-CHCC PF10276.4 AEO68565.1 - 0.17 11.7 4.2 3.4 7.5 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger domain Rtt106 PF08512.7 AEO68566.1 - 3.5e-24 84.6 0.0 8.7e-24 83.3 0.0 1.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CVNH PF08881.5 AEO68567.1 - 4e-32 110.5 0.1 4.4e-32 110.4 0.1 1.0 1 0 0 1 1 1 1 CVNH domain CD4-extracel PF09191.5 AEO68567.1 - 0.094 12.7 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 CD4, extracellular Glyco_hydro_3 PF00933.16 AEO68568.1 - 1.4e-62 211.3 0.0 1.9e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO68568.1 - 2.7e-62 210.2 0.3 4.4e-62 209.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO68568.1 - 2.8e-24 84.8 0.3 2.8e-24 84.8 0.2 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain CARDB PF07705.6 AEO68568.1 - 0.025 14.6 0.1 0.072 13.1 0.1 1.7 1 0 0 1 1 1 0 CARDB Sugar-bind PF04198.8 AEO68568.1 - 0.07 12.0 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative sugar-binding domain Glyco_hydro_31 PF01055.21 AEO68569.1 - 1.4e-113 380.0 0.0 1.7e-113 379.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 AEO68569.1 - 1.3e-17 63.3 0.0 7.1e-17 61.0 0.0 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like Sugar_tr PF00083.19 AEO68570.1 - 1.3e-99 333.8 23.2 1.5e-99 333.6 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO68570.1 - 4.2e-29 101.3 24.7 4.2e-29 101.3 17.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO68570.1 - 6.1e-06 24.7 1.6 6.1e-06 24.7 1.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 AEO68570.1 - 0.00041 19.1 1.5 0.00041 19.1 1.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF791) Glyco_hydro_11 PF00457.12 AEO68571.1 - 4.5e-50 169.5 14.1 5.9e-50 169.1 9.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 W_rich_C PF07483.6 AEO68571.1 - 0.024 14.3 3.3 0.031 13.9 1.5 1.7 1 1 1 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain Fungal_trans PF04082.13 AEO68572.1 - 1.8e-16 59.8 0.0 2.5e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 AEO68573.1 - 3.6e-43 147.6 28.4 3.6e-43 147.6 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO68573.1 - 1.2e-08 34.0 10.1 1.2e-08 34.0 7.0 3.3 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 AEO68573.1 - 2.1e-05 22.9 5.6 3.2e-05 22.3 3.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 AEO68573.1 - 0.15 10.0 2.1 0.2 9.6 0.5 1.9 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family WD40 PF00400.27 AEO68574.1 - 1.5e-08 34.1 1.3 2.1e-06 27.4 0.1 4.0 3 0 0 3 3 3 1 WD domain, G-beta repeat PGAP1 PF07819.8 AEO68574.1 - 9.6e-06 25.3 0.0 6.4e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 AEO68574.1 - 2.5e-05 23.6 0.0 5.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 AEO68574.1 - 8.2e-05 22.5 0.1 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO68574.1 - 0.012 15.3 0.0 0.035 13.8 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family eIF2A PF08662.6 AEO68574.1 - 0.054 13.1 0.0 2.1 8.0 0.0 2.8 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Fructosamin_kin PF03881.9 AEO68575.1 - 8.3e-29 100.4 0.0 1e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 AEO68575.1 - 0.0085 15.8 0.0 0.021 14.5 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.11 AEO68576.1 - 6.6e-23 80.9 0.4 6.6e-23 80.9 0.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_61 PF03443.9 AEO68577.1 - 1.4e-46 159.0 0.0 1.6e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Aa_trans PF01490.13 AEO68578.1 - 1.5e-42 145.5 33.6 1.8e-42 145.2 23.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.1 AEO68578.1 - 5.3 6.7 11.5 0.2 11.3 2.0 3.1 3 1 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase MFS_1 PF07690.11 AEO68579.1 - 1.3e-33 116.1 33.2 1.3e-33 116.1 23.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO68579.1 - 2.7e-12 46.0 37.5 2.2e-10 39.7 9.0 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 AEO68579.1 - 3e-07 29.0 9.4 1.1e-06 27.2 4.0 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 AEO68579.1 - 0.0052 16.5 2.1 4.1 7.2 0.0 4.0 3 2 0 3 3 3 2 MFS_1 like family ketoacyl-synt PF00109.21 AEO68580.1 - 1.1e-73 247.8 0.0 1.2e-73 247.7 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 AEO68580.1 - 2.4e-06 26.7 0.0 3.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain MFS_1 PF07690.11 AEO68581.1 - 2.7e-39 134.8 46.5 6.1e-39 133.7 32.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO68581.1 - 4.1e-08 32.2 14.1 4.1e-08 32.2 9.8 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter ATG22 PF11700.3 AEO68581.1 - 3e-06 26.0 10.9 3e-06 26.0 7.5 3.4 3 1 1 4 4 4 2 Vacuole effluxer Atg22 like DUF3357 PF11837.3 AEO68581.1 - 0.26 11.1 1.5 15 5.4 0.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) Fungal_trans PF04082.13 AEO68582.1 - 6e-21 74.4 0.1 9.1e-21 73.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 AEO68583.1 - 1.1e-21 77.3 0.4 2.2e-09 36.8 0.2 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 AEO68583.1 - 2.5e-07 30.6 0.0 6.8e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO68583.1 - 0.0008 18.4 0.1 0.0029 16.5 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO68583.1 - 0.0013 17.6 0.0 0.0025 16.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 AEO68583.1 - 0.0016 18.8 0.1 0.019 15.3 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO68583.1 - 0.048 12.7 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 AEO68583.1 - 0.054 13.5 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO68583.1 - 0.057 13.3 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO68583.1 - 0.096 11.5 0.1 0.94 8.3 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein LANC_like PF05147.8 AEO68585.1 - 2.7e-21 75.5 0.0 1.4e-19 69.9 0.0 2.0 2 0 0 2 2 2 2 Lanthionine synthetase C-like protein Glyco_hydro_10 PF00331.15 AEO68586.1 - 1.1e-90 303.9 0.0 1.2e-90 303.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 MFS_1 PF07690.11 AEO68587.1 - 7.7e-19 67.6 22.3 7.7e-19 67.6 15.4 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO68587.1 - 3.8e-06 25.7 6.3 3.8e-06 25.7 4.4 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO68588.1 - 7.5e-46 156.4 55.0 9e-38 129.8 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO68588.1 - 1.4e-07 30.4 9.8 1.4e-07 30.4 6.8 2.5 2 2 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 AEO68588.1 - 8.4 4.3 9.5 4.8 5.1 1.8 2.9 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ADH_N PF08240.7 AEO68589.1 - 8.1e-10 38.4 0.0 3.4e-09 36.4 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO68589.1 - 9.8e-09 34.8 0.0 1.8e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_4 PF01565.18 AEO68590.1 - 4.3e-26 91.0 1.6 8.4e-26 90.0 0.9 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 AEO68590.1 - 1.9e-07 30.8 0.0 5.7e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 AEO68591.1 - 3.6e-35 121.3 41.1 1.8e-34 119.0 26.9 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 AEO68592.1 - 7.8e-25 87.7 2.4 1.2e-24 87.1 1.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO68592.1 - 3e-16 59.9 0.2 3.4e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO68592.1 - 1.1e-09 38.2 2.0 1.5e-09 37.7 0.9 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO68592.1 - 0.00034 20.6 0.1 0.0007 19.6 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 AEO68592.1 - 0.0044 16.3 0.0 0.0073 15.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 AEO68592.1 - 0.0062 15.9 0.0 0.0096 15.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 AEO68592.1 - 0.0088 16.4 0.1 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 AEO68592.1 - 0.011 14.7 0.1 0.021 13.6 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain DFP PF04127.10 AEO68592.1 - 0.064 12.8 0.2 0.13 11.8 0.2 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein ADH_zinc_N PF00107.21 AEO68592.1 - 0.08 12.4 0.3 0.22 11.0 0.1 1.8 1 1 1 2 2 2 0 Zinc-binding dehydrogenase p450 PF00067.17 AEO68593.1 - 8.2e-67 225.7 0.0 9.8e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 AEO68594.1 - 9.9e-14 50.6 0.0 1.8e-13 49.7 0.0 1.4 2 0 0 2 2 2 1 Transferase family GPP34 PF05719.6 AEO68594.1 - 0.072 13.1 0.4 0.17 11.9 0.1 1.7 2 0 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) FAD_binding_4 PF01565.18 AEO68595.1 - 2e-19 69.4 3.8 4e-19 68.4 2.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO68595.1 - 7.1e-08 32.2 0.0 1.8e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like INCENP_ARK-bind PF03941.10 AEO68595.1 - 0.0058 16.4 0.0 2.6 7.9 0.0 3.4 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region Fungal_trans PF04082.13 AEO68596.1 - 6.5e-15 54.7 0.1 8.9e-15 54.2 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO68596.1 - 8.6e-09 35.1 6.8 1.5e-08 34.4 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 AEO68597.1 - 3.5e-70 236.3 4.9 6.8e-69 232.1 0.4 3.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 AEO68597.1 - 6.5e-37 127.5 0.1 3.3e-34 118.6 0.0 2.3 2 0 0 2 2 2 2 Acyl transferase domain NAD_binding_4 PF07993.7 AEO68597.1 - 1.1e-31 109.6 0.0 1.7e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 AEO68597.1 - 1.3e-31 108.8 0.4 4e-31 107.3 0.0 2.1 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 AEO68597.1 - 1.2e-14 54.5 0.0 3.3e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 AEO68597.1 - 1.1e-11 44.7 0.1 3.2e-11 43.3 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 AEO68597.1 - 2.3e-07 30.6 0.0 1.6e-06 27.9 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO68597.1 - 8.5e-07 29.3 0.0 5e-06 26.9 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO68597.1 - 1.2e-06 28.1 0.0 2.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 AEO68597.1 - 4.7e-06 25.7 0.1 9.6e-06 24.7 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.16 AEO68597.1 - 9.9e-06 25.1 0.0 2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.1 AEO68597.1 - 1.1e-05 25.7 0.0 6.9e-05 23.1 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.20 AEO68597.1 - 2.1e-05 24.5 2.9 0.00013 21.9 0.3 2.9 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_18 PF12847.2 AEO68597.1 - 8.2e-05 23.1 0.0 0.00054 20.5 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain DXP_reductoisom PF02670.11 AEO68597.1 - 0.00082 19.9 0.4 0.026 15.0 0.0 3.1 3 0 0 3 3 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase KR PF08659.5 AEO68597.1 - 0.0011 18.6 0.1 0.0032 17.1 0.1 1.8 1 0 0 1 1 1 1 KR domain Ubie_methyltran PF01209.13 AEO68597.1 - 0.012 14.7 0.0 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Semialdhyde_dh PF01118.19 AEO68597.1 - 0.016 15.4 0.1 0.39 11.0 0.0 3.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 AEO68597.1 - 0.074 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ABC_trans_N PF14510.1 AEO68597.1 - 0.09 12.8 0.2 0.97 9.5 0.0 2.4 2 0 0 2 2 2 0 ABC-transporter extracellular N-terminal Polysacc_synt_2 PF02719.10 AEO68597.1 - 0.15 10.8 0.0 0.29 9.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 AEO68597.1 - 0.19 10.9 0.1 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family RrnaAD PF00398.15 AEO68597.1 - 0.63 9.0 0.0 1.2 8.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FSH1 PF03959.8 AEO68598.1 - 5e-31 107.8 0.0 6.6e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 AEO68598.1 - 0.00012 21.8 0.0 0.00026 20.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO68598.1 - 0.00066 19.6 7.3 0.0016 18.4 5.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 AEO68598.1 - 0.013 14.8 0.0 0.035 13.5 0.0 1.8 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 AEO68598.1 - 0.094 12.2 0.7 0.34 10.4 0.1 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold FAD_binding_3 PF01494.14 AEO68601.1 - 1.4e-17 63.7 2.7 1.1e-10 41.0 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 AEO68601.1 - 0.00011 22.0 0.0 0.0003 20.5 0.0 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 AEO68601.1 - 0.00012 21.1 1.7 0.00074 18.5 0.7 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO68601.1 - 0.012 15.6 0.2 0.038 13.9 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 AEO68601.1 - 0.13 11.0 0.0 3.3 6.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase DUF4516 PF14990.1 AEO68602.1 - 0.13 11.8 0.3 0.22 11.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) PEP_mutase PF13714.1 AEO68604.1 - 1.2e-58 198.1 5.1 1.4e-58 197.9 3.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Pilus_CpaD PF09476.5 AEO68604.1 - 0.053 12.9 1.1 0.072 12.5 0.2 1.7 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) Sugarporin_N PF11471.3 AEO68604.1 - 0.16 11.6 1.8 0.23 11.1 0.2 1.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension RdRP PF05183.7 AEO68606.1 - 1e-123 414.1 0.0 1.4e-123 413.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Fungal_trans PF04082.13 AEO68607.1 - 4.4e-19 68.3 3.0 7.3e-19 67.6 2.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO68607.1 - 3.9e-06 26.6 16.4 8.6e-06 25.5 11.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M14 PF00246.19 AEO68608.1 - 3.5e-69 233.5 0.0 4e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase 2OG-FeII_Oxy PF03171.15 AEO68609.1 - 0.00034 20.8 0.0 0.0006 20.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 AEO68609.1 - 0.00057 20.3 0.0 0.00092 19.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Pkinase PF00069.20 AEO68610.1 - 6.1e-08 32.1 0.0 9e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain FhuF PF06276.7 AEO68610.1 - 0.06 13.3 0.2 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter Cofilin_ADF PF00241.15 AEO68611.1 - 1.1e-22 80.3 0.0 1.5e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein NAD_binding_8 PF13450.1 AEO68613.1 - 1.1e-10 41.4 0.5 2.9e-10 40.0 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO68613.1 - 4.5e-08 32.3 0.1 8.3e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO68613.1 - 1.5e-07 30.6 1.7 3.3e-07 29.5 1.0 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 AEO68613.1 - 1.9e-05 23.3 0.7 3e-05 22.6 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 AEO68613.1 - 2.7e-05 24.3 0.2 0.00094 19.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO68613.1 - 3e-05 23.3 2.0 6.9e-05 22.1 1.4 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO68613.1 - 0.00013 22.3 0.3 0.0003 21.1 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 AEO68613.1 - 0.00018 20.6 0.7 0.00032 19.8 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AEO68613.1 - 0.00032 20.6 0.2 0.00095 19.0 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO68613.1 - 0.00066 18.8 0.2 0.0015 17.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family PepSY PF03413.14 AEO68613.1 - 0.009 16.6 0.2 0.1 13.2 0.0 2.3 2 0 0 2 2 2 1 Peptidase propeptide and YPEB domain Lycopene_cycl PF05834.7 AEO68613.1 - 0.011 14.6 0.2 0.017 14.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein IlvN PF07991.7 AEO68613.1 - 0.018 14.4 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Amino_oxidase PF01593.19 AEO68613.1 - 0.025 13.6 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GIDA PF01134.17 AEO68613.1 - 0.025 13.4 0.5 0.037 12.8 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.1 AEO68613.1 - 0.032 13.1 0.1 4.9 5.9 0.1 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 AEO68613.1 - 0.12 11.9 1.2 0.22 11.1 0.8 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 AEO68613.1 - 0.22 10.1 1.5 0.33 9.5 1.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Asp PF00026.18 AEO68614.1 - 8.6e-34 117.2 0.0 1.5e-33 116.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Serglycin PF04360.7 AEO68614.1 - 0.0032 17.2 4.6 0.0093 15.7 3.2 1.8 1 0 0 1 1 1 1 Serglycin Rax2 PF12768.2 AEO68614.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Peptidase_C2 PF00648.16 AEO68616.1 - 4.6e-52 176.8 0.7 8.6e-36 123.4 0.4 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease MFS_1 PF07690.11 AEO68617.1 - 5.9e-23 81.1 45.5 5.9e-23 81.1 31.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO68617.1 - 3.7e-08 32.3 8.2 3.7e-08 32.3 5.7 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter DUF4620 PF15399.1 AEO68617.1 - 0.7 10.0 3.6 1.1 9.4 0.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4620) DUF2614 PF11023.3 AEO68617.1 - 4.5 7.0 5.4 0.8 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) Ribosomal_S7e PF01251.13 AEO68618.1 - 3.7e-82 274.4 0.3 4.1e-82 274.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e NUDIX PF00293.23 AEO68620.1 - 1.8e-07 30.8 0.3 2.8e-07 30.2 0.2 1.3 1 0 0 1 1 1 1 NUDIX domain ADH_N PF08240.7 AEO68622.1 - 3.8e-25 87.7 3.2 6e-25 87.1 2.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO68622.1 - 2.5e-13 49.7 0.2 7.1e-13 48.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 AEO68622.1 - 1.4e-05 24.3 0.1 2.7e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dynactin_p62 PF05502.8 AEO68623.1 - 1.8e-183 610.7 0.0 2.2e-183 610.4 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family DUF2296 PF10058.4 AEO68623.1 - 2 8.2 0.0 2 8.2 0.0 3.5 4 0 0 4 4 4 0 Predicted integral membrane metal-binding protein (DUF2296) EBP PF05241.7 AEO68625.1 - 5.3e-06 25.5 2.9 1.1e-05 24.4 2.0 1.6 1 1 0 1 1 1 1 Emopamil binding protein TM140 PF14985.1 AEO68625.1 - 0.0036 17.0 0.6 0.0054 16.4 0.4 1.3 1 0 0 1 1 1 1 TM140 protein family BolA PF01722.13 AEO68626.1 - 8.1e-15 54.5 0.0 1.2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein Peptidase_S8 PF00082.17 AEO68627.1 - 2.1e-48 164.9 0.0 9e-47 159.5 0.0 2.5 2 1 0 2 2 2 1 Subtilase family DUF1034 PF06280.7 AEO68627.1 - 8.9e-16 58.2 0.2 2.8e-15 56.7 0.1 1.9 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 AEO68627.1 - 3.3e-13 49.1 0.4 1.5e-12 47.0 0.1 2.3 2 0 0 2 2 2 1 PA domain FlgD_ig PF13860.1 AEO68627.1 - 2.2e-05 24.0 0.0 6.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 FlgD Ig-like domain FAD_binding_8 PF08022.7 AEO68631.1 - 3.3e-15 55.8 0.0 6.3e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 AEO68631.1 - 6.6e-14 52.0 13.1 6.6e-14 52.0 9.1 2.3 1 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 AEO68631.1 - 9.6e-10 38.5 0.0 1.5e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.1 AEO68631.1 - 1.3 9.2 10.5 7.8 6.7 1.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) tRNA-synt_1d PF00750.14 AEO68632.1 - 4.4e-81 272.4 1.1 8.6e-81 271.4 0.8 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 AEO68632.1 - 1.1e-27 96.3 0.1 2.3e-27 95.3 0.1 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 AEO68632.1 - 0.0069 16.9 0.0 0.016 15.7 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain DUF2203 PF09969.4 AEO68632.1 - 0.04 14.1 2.4 0.33 11.1 1.1 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) tRNA-synt_1g PF09334.6 AEO68632.1 - 0.06 12.0 0.0 0.65 8.5 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (M) p450 PF00067.17 AEO68633.1 - 7.2e-56 189.6 0.0 1e-55 189.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SLAC1 PF03595.12 AEO68634.1 - 6.3e-55 186.1 24.2 7.6e-55 185.8 16.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF485 PF04341.7 AEO68634.1 - 0.023 14.3 0.7 0.023 14.3 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function, DUF485 RINGv PF12906.2 AEO68635.1 - 1.3e-16 60.3 7.6 2.1e-16 59.6 5.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 AEO68635.1 - 0.05 13.4 8.2 0.084 12.7 5.7 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 AEO68635.1 - 0.074 12.7 4.6 0.12 12.0 3.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AEO68635.1 - 0.4 10.5 2.8 1 9.2 1.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 AEO68635.1 - 8.6 6.0 6.6 14 5.3 4.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 AEO68635.1 - 8.9 6.3 6.6 16 5.5 4.6 1.4 1 0 0 1 1 1 0 RING-like domain ATG_C PF09333.6 AEO68636.1 - 2.5 8.2 11.2 6.3 7.0 2.0 3.7 2 2 1 3 3 3 0 ATG C terminal domain HeLo PF14479.1 AEO68637.1 - 4.6e-07 29.8 0.4 0.0022 17.7 0.1 2.8 2 1 1 3 3 3 2 Prion-inhibition and propagation PT PF04886.7 AEO68637.1 - 0.88 8.9 18.7 0.02 14.1 6.9 2.6 2 0 0 2 2 2 0 PT repeat SR-25 PF10500.4 AEO68638.1 - 0.17 11.3 11.2 0.28 10.6 7.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein UDPGT PF00201.13 AEO68639.1 - 7.3e-05 21.5 0.1 0.00013 20.6 0.1 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase COesterase PF00135.23 AEO68640.1 - 5.7e-87 292.6 0.1 7.5e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO68640.1 - 1.2e-06 28.2 0.3 6.8e-06 25.7 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Herpes_gE PF02480.11 AEO68641.1 - 0.00035 18.9 0.0 0.00047 18.5 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Shisa PF13908.1 AEO68641.1 - 0.035 14.2 0.0 0.075 13.1 0.0 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 AEO68641.1 - 0.088 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SLAC1 PF03595.12 AEO68641.1 - 0.095 11.3 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Voltage-dependent anion channel SIT PF15330.1 AEO68641.1 - 0.12 12.5 0.0 0.23 11.5 0.0 1.5 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT IncA PF04156.9 AEO68641.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 IncA protein DUF221 PF02714.10 AEO68642.1 - 4.7e-77 259.0 7.5 8.1e-77 258.2 5.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AEO68642.1 - 4.8e-42 143.1 1.9 4.8e-42 143.1 1.3 1.8 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 AEO68642.1 - 2.6e-12 47.0 0.0 6.5e-12 45.8 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 AEO68642.1 - 0.0032 17.4 0.0 0.0073 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO68642.1 - 0.0072 15.9 0.0 0.035 13.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO68642.1 - 0.016 15.0 0.0 0.087 12.6 0.0 2.2 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3779 PF12621.3 AEO68643.1 - 5.6e-26 90.2 0.0 6.4e-26 90.0 0.0 1.1 1 0 0 1 1 1 1 Phosphate metabolism protein CBM_21 PF03370.8 AEO68644.1 - 1.7e-36 124.6 0.7 3.1e-36 123.7 0.5 1.5 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit ADH_zinc_N_2 PF13602.1 AEO68645.1 - 3.9e-20 73.0 0.0 5e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 AEO68645.1 - 6.5e-19 67.7 0.0 1.1e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 AEO68645.1 - 0.0049 16.3 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 AEO68645.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DFP PF04127.10 AEO68645.1 - 0.021 14.4 0.0 0.078 12.5 0.0 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein NAD_binding_10 PF13460.1 AEO68645.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding APG17 PF04108.7 AEO68646.1 - 9.8e-105 350.7 0.9 1.3e-104 350.2 0.6 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF4358 PF14270.1 AEO68646.1 - 1.1 9.1 5.5 0.45 10.4 0.2 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4358) RIO1 PF01163.17 AEO68647.1 - 1.8e-69 232.8 0.4 3.9e-69 231.8 0.0 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 AEO68647.1 - 0.0001 22.1 3.1 0.013 15.2 0.3 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 AEO68647.1 - 0.0004 19.5 0.2 0.16 11.0 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Plasmod_dom_1 PF09715.5 AEO68648.1 - 2.1 8.3 7.3 0.21 11.5 1.0 2.3 2 1 1 3 3 3 0 Plasmodium protein of unknown function (Plasmod_dom_1) MFS_1 PF07690.11 AEO68651.1 - 1.9e-48 165.0 34.4 1.9e-48 165.0 23.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO68651.1 - 1.3e-16 60.2 7.5 1.3e-16 60.2 5.2 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 AEO68651.1 - 0.00012 20.4 1.2 0.00017 19.9 0.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 AEO68651.1 - 0.00099 17.2 3.0 0.00099 17.2 2.1 2.0 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family TMPIT PF07851.8 AEO68651.1 - 0.093 11.7 2.3 0.18 10.8 1.6 1.4 1 0 0 1 1 1 0 TMPIT-like protein Pkinase PF00069.20 AEO68653.1 - 7.5e-22 77.7 0.0 1e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO68653.1 - 0.00052 19.1 0.0 0.31 10.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 AEO68653.1 - 0.38 10.4 3.5 2.1 7.9 0.0 2.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family BNR PF02012.15 AEO68654.1 - 3.8e-07 28.9 1.8 0.4 10.6 0.0 3.8 3 0 0 3 3 3 3 BNR/Asp-box repeat BNR_2 PF13088.1 AEO68654.1 - 4.8e-07 29.3 0.0 0.0012 18.1 0.0 3.4 3 1 0 3 3 3 2 BNR repeat-like domain Med22 PF06179.7 AEO68655.1 - 3.5e-09 36.6 0.0 4.7e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PseudoU_synth_1 PF01416.15 AEO68656.1 - 9.9e-22 77.3 0.0 2e-10 41.0 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase MgtE_N PF03448.12 AEO68656.1 - 0.017 15.3 0.2 0.044 14.0 0.1 1.6 1 0 0 1 1 1 0 MgtE intracellular N domain DUF2344 PF10105.4 AEO68656.1 - 0.087 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) DUF3328 PF11807.3 AEO68657.1 - 7.7e-13 48.6 0.3 9.2e-13 48.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Catalase PF00199.14 AEO68659.1 - 4.7e-157 522.6 0.1 5.8e-157 522.2 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 AEO68659.1 - 9.5e-23 79.8 0.1 1.8e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 AEO68659.1 - 4.8e-09 35.8 0.1 8.8e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Fungal_trans PF04082.13 AEO68661.1 - 1.2e-06 27.6 0.0 2.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO68661.1 - 3.1e-05 23.7 7.1 5.6e-05 22.9 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 AEO68662.1 - 2.9e-16 59.1 55.0 3.7e-12 45.6 15.3 3.0 1 1 3 4 4 4 3 Major Facilitator Superfamily Cutinase PF01083.17 AEO68662.1 - 0.0036 17.0 0.3 0.034 13.9 0.2 2.1 1 1 1 2 2 2 2 Cutinase RVT_1 PF00078.22 AEO68663.1 - 6.3e-05 22.4 0.6 6.3e-05 22.4 0.4 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exonuc_V_gamma PF04257.9 AEO68663.1 - 0.19 9.6 0.5 0.25 9.2 0.3 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit RVT_1 PF00078.22 AEO68664.1 - 0.0079 15.5 0.2 0.012 14.9 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ACT PF01842.20 AEO68664.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 ACT domain TRIQK PF15168.1 AEO68665.1 - 0.067 13.1 0.0 0.085 12.7 0.0 1.2 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family DUF812 PF05667.6 AEO68666.1 - 4.4 5.6 7.1 0.38 9.1 1.8 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF812) SET PF00856.23 AEO68667.1 - 0.00029 21.1 0.0 0.0011 19.3 0.0 2.0 2 0 0 2 2 2 1 SET domain ArsA_ATPase PF02374.10 AEO68667.1 - 0.041 12.9 0.0 0.061 12.3 0.0 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase TPR_12 PF13424.1 AEO68667.1 - 0.055 13.3 0.8 0.091 12.7 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M24 PF00557.19 AEO68668.1 - 3.2e-54 183.6 0.1 4.2e-54 183.2 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 AEO68668.1 - 9.7e-26 89.7 0.0 1.9e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain CHZ PF09649.5 AEO68669.1 - 0.12 11.6 0.1 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Histone chaperone domain CHZ Con-6 PF10346.4 AEO68670.1 - 2.7e-32 109.8 4.4 6.5e-16 57.4 0.5 2.1 2 0 0 2 2 2 2 Conidiation protein 6 DUF4230 PF14014.1 AEO68670.1 - 0.028 14.3 1.4 0.28 11.0 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4230) MRP-L47 PF06984.8 AEO68670.1 - 0.053 13.4 0.1 0.1 12.4 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) SpoIIIAH PF12685.2 AEO68670.1 - 0.68 9.3 4.9 6.1 6.2 3.4 2.0 1 1 0 1 1 1 0 SpoIIIAH-like protein Cyclin PF08613.6 AEO68671.1 - 5.2e-40 137.2 0.0 8.1e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AEO68671.1 - 0.0073 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain TPP_enzyme_N PF02776.13 AEO68672.1 - 9.3e-40 135.9 0.3 7.1e-39 133.0 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 AEO68672.1 - 1.2e-22 80.1 0.0 2.5e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 AEO68672.1 - 1.2e-20 73.6 0.0 9.2e-20 70.7 0.0 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain NTP_transf_3 PF12804.2 AEO68672.1 - 0.0019 18.2 0.2 0.03 14.4 0.0 2.9 2 1 0 2 2 2 1 MobA-like NTP transferase domain Herpes_capsid PF06112.6 AEO68672.1 - 1.1 9.2 5.4 2.1 8.3 3.7 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein LysM PF01476.15 AEO68673.1 - 5.4e-29 99.8 0.9 1.9e-07 30.8 0.0 6.4 6 0 0 6 6 6 5 LysM domain DUF1153 PF06627.6 AEO68673.1 - 0.05 13.4 0.1 69 3.4 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1153) Lipase_GDSL_2 PF13472.1 AEO68674.1 - 3.9e-12 46.6 0.0 4.7e-11 43.1 0.0 2.3 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO68674.1 - 1.9e-06 27.8 4.4 8e-06 25.8 3.1 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase adh_short PF00106.20 AEO68675.1 - 5e-19 68.8 4.2 8e-19 68.1 2.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO68675.1 - 1.6e-09 37.6 0.4 2.6e-09 36.9 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO68675.1 - 0.0077 15.6 0.1 0.084 12.2 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 AEO68675.1 - 0.023 14.8 0.2 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Reprolysin_2 PF13574.1 AEO68676.1 - 0.00041 20.4 0.0 0.00075 19.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 AEO68676.1 - 0.00071 19.0 0.0 0.012 15.0 0.1 2.4 3 0 0 3 3 3 1 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.1 AEO68676.1 - 0.0056 16.6 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 AEO68676.1 - 0.0065 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 AEO68676.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.1 AEO68676.1 - 0.018 15.5 0.0 0.031 14.8 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 AEO68676.1 - 0.048 13.4 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Glyco_hydro_18 PF00704.23 AEO68677.1 - 5.4e-66 223.3 0.2 6.7e-66 223.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 AEO68677.1 - 4.9e-08 32.8 9.9 4.9e-08 32.8 6.9 2.8 2 1 0 2 2 2 1 Chitin recognition protein Lipase_GDSL_2 PF13472.1 AEO68681.1 - 9.3e-09 35.6 0.1 3.2e-08 33.9 0.1 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SchA_CurD PF04486.7 AEO68681.1 - 0.00062 19.5 0.1 0.0011 18.8 0.1 1.3 1 0 0 1 1 1 1 SchA/CurD like domain Alginate_lyase2 PF08787.6 AEO68682.1 - 5.1e-40 137.5 0.0 5.8e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase SH3_9 PF14604.1 AEO68683.1 - 0.038 13.5 0.1 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Variant SH3 domain HSP20 PF00011.16 AEO68685.1 - 5.7e-19 67.8 0.0 2.2e-12 46.6 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family DUF2360 PF10152.4 AEO68685.1 - 0.11 12.7 2.7 0.15 12.3 1.9 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) APH PF01636.18 AEO68686.1 - 4.7e-06 26.4 0.0 6.9e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Chitin_synth_1N PF08407.6 AEO68686.1 - 0.025 14.2 0.1 0.1 12.3 0.0 2.0 3 0 0 3 3 3 0 Chitin synthase N-terminal APH PF01636.18 AEO68687.1 - 0.047 13.4 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3328 PF11807.3 AEO68688.1 - 6e-53 179.7 1.8 8e-53 179.3 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 AEO68689.1 - 2.1e-27 96.2 2.0 6.9e-27 94.5 1.4 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 AEO68690.1 - 6.6e-48 163.2 0.0 8.9e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) tify PF06200.9 AEO68690.1 - 0.15 11.3 0.0 0.38 10.0 0.0 1.7 1 0 0 1 1 1 0 tify domain DUF3328 PF11807.3 AEO68691.1 - 9.2e-23 81.0 0.1 1.1e-22 80.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TPR_16 PF13432.1 AEO68692.1 - 0.056 14.1 3.9 7.9 7.2 1.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 AEO68692.1 - 0.065 13.6 2.8 6.1 7.5 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF3328 PF11807.3 AEO68693.1 - 2.2e-30 105.9 0.5 2.5e-30 105.7 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Cytochrom_B_N PF00033.14 AEO68693.1 - 0.084 12.2 0.4 0.12 11.6 0.3 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF3328 PF11807.3 AEO68694.1 - 9.3e-28 97.3 1.8 1.1e-27 97.1 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ank PF00023.25 AEO68695.1 - 6.4e-27 91.9 0.8 1.8e-08 33.7 0.1 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 AEO68695.1 - 5.9e-24 84.2 0.2 8.8e-24 83.6 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AEO68695.1 - 8.9e-18 62.6 0.2 0.00017 21.4 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 AEO68695.1 - 1.2e-17 63.5 2.1 3.3e-10 39.8 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO68695.1 - 3.9e-17 62.2 2.0 3.8e-07 30.4 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) SchA_CurD PF04486.7 AEO68695.1 - 0.013 15.2 0.1 0.02 14.7 0.1 1.4 1 0 0 1 1 1 0 SchA/CurD like domain DUF4573 PF15140.1 AEO68696.1 - 1.8e-29 102.5 2.6 1.8e-14 53.7 0.6 3.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) HTH_39 PF14090.1 AEO68696.1 - 0.00069 19.0 0.3 4.4 6.8 0.0 3.8 3 1 1 4 4 4 2 Helix-turn-helix domain SAF PF08666.7 AEO68696.1 - 0.011 16.1 0.2 64 4.0 0.0 5.0 3 1 1 4 4 4 0 SAF domain Abhydrolase_6 PF12697.2 AEO68697.1 - 7e-17 62.0 4.8 8.8e-17 61.7 3.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO68697.1 - 2.7e-06 27.1 0.0 0.00013 21.5 0.0 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO68697.1 - 0.00035 20.3 1.6 0.00062 19.5 1.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family ATP_transf PF09830.4 AEO68698.1 - 1.3e-16 60.1 0.2 2.1e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 AEO68698.1 - 0.12 12.9 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 HIT domain Myb_DNA-bind_6 PF13921.1 AEO68699.1 - 6.9e-06 26.0 0.3 1.1e-05 25.3 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO68699.1 - 0.00011 22.1 0.3 0.00025 21.0 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rap1_C PF11626.3 AEO68699.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Mito_fiss_reg PF05308.6 AEO68699.1 - 5 6.4 8.7 0.78 9.0 2.8 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator adh_short PF00106.20 AEO68702.1 - 3e-29 102.1 0.3 3.8e-29 101.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO68702.1 - 2.3e-16 60.3 0.0 3.2e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO68702.1 - 2.3e-16 59.9 0.1 3.4e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO68702.1 - 3e-06 27.3 0.0 6.3e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 AEO68702.1 - 0.0014 17.7 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) TilS PF09179.6 AEO68703.1 - 0.024 14.6 1.8 0.096 12.7 1.2 2.0 1 0 0 1 1 1 0 TilS substrate binding domain tRNA-synt_1d PF00750.14 AEO68704.1 - 7.1e-74 248.7 0.0 1.4e-73 247.7 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 AEO68704.1 - 1.3e-25 89.6 0.0 2.8e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain NmrA PF05368.8 AEO68707.1 - 2.8e-36 124.9 0.0 3.7e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO68707.1 - 2e-21 76.8 0.7 2.9e-21 76.3 0.5 1.2 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 AEO68707.1 - 0.00047 20.5 0.5 0.0015 18.8 0.1 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 AEO68707.1 - 0.00064 18.5 0.0 0.0014 17.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 AEO68707.1 - 0.0034 17.3 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain DUF1308 PF07000.6 AEO68708.1 - 4.1e-27 94.7 0.0 6.1e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Prok-RING_2 PF14445.1 AEO68708.1 - 1.2 9.1 4.5 1.5 8.8 0.3 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 2 DUF3484 PF11983.3 AEO68709.1 - 0.0037 18.0 1.5 0.0037 18.0 1.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3484) WTX PF09422.5 AEO68709.1 - 0.022 13.7 8.0 0.036 13.0 5.5 1.4 1 1 0 1 1 1 0 WTX protein Pinin_SDK_memA PF04696.8 AEO68709.1 - 0.039 13.5 6.5 0.069 12.7 4.5 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Herpes_UL6 PF01763.11 AEO68709.1 - 0.077 11.1 4.1 0.087 10.9 2.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like RapA_C PF12137.3 AEO68709.1 - 0.11 11.2 5.2 0.15 10.8 3.6 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal CDC37_N PF03234.9 AEO68709.1 - 0.13 12.5 4.5 0.16 12.3 3.1 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding HrpA_pilin PF09589.5 AEO68709.1 - 2.6 8.5 8.7 3.3 8.1 6.0 1.3 1 0 0 1 1 1 0 HrpA pilus formation protein DUF2383 PF09537.5 AEO68709.1 - 4.6 7.5 7.6 3.3 7.9 3.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) HSP9_HSP12 PF04119.7 AEO68709.1 - 6.4 6.9 9.2 0.83 9.7 3.0 2.0 2 0 0 2 2 2 0 Heat shock protein 9/12 PP_kinase_N PF13089.1 AEO68709.1 - 7.5 6.6 6.6 0.93 9.6 1.4 1.7 2 0 0 2 2 2 0 Polyphosphate kinase N-terminal domain Mannosyl_trans3 PF11051.3 AEO68710.1 - 2.9e-46 158.0 0.0 4.5e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative TPR_12 PF13424.1 AEO68712.1 - 2.1e-28 98.0 1.4 7.2e-13 48.2 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 AEO68712.1 - 7.9e-24 82.8 6.2 2.9e-06 27.0 0.0 6.4 6 1 1 7 7 7 4 Tetratricopeptide repeat NB-ARC PF00931.17 AEO68712.1 - 3.4e-10 39.2 0.0 7.3e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.1 AEO68712.1 - 6.8e-08 31.7 1.7 0.0094 15.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.1 AEO68712.1 - 4.1e-07 30.2 0.0 3.7e-06 27.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain TPR_14 PF13428.1 AEO68712.1 - 0.0048 17.4 1.3 9.8 7.1 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 AEO68712.1 - 0.0051 17.4 0.1 1.6 9.4 0.0 4.0 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 AEO68712.1 - 0.0068 16.2 0.4 3.6 7.7 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 AEO68712.1 - 0.011 15.9 1.0 3.3 8.1 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO68712.1 - 0.13 11.8 0.1 10 5.8 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 AEO68712.1 - 0.19 12.2 8.3 26 5.6 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 AEO68712.1 - 1.3 9.3 3.3 13 6.3 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat AA_permease PF00324.16 AEO68713.1 - 1.3e-101 340.3 43.3 1.6e-101 340.0 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO68713.1 - 1.1e-29 103.2 48.1 1.3e-29 102.9 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease NUDIX PF00293.23 AEO68714.1 - 3.5e-16 59.0 0.9 7e-16 58.1 0.2 1.7 2 0 0 2 2 2 1 NUDIX domain NUDE_C PF04880.8 AEO68715.1 - 1.3e-20 74.4 1.4 1.3e-20 74.4 1.0 4.7 1 1 1 2 2 2 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 AEO68715.1 - 0.00095 19.4 7.5 0.00095 19.4 5.2 3.7 2 1 2 4 4 4 1 Protein of unknown function (DUF904) WEMBL PF05701.6 AEO68715.1 - 0.041 12.3 27.9 0.061 11.7 19.3 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light IncA PF04156.9 AEO68715.1 - 0.08 12.5 31.1 0.17 11.4 14.0 2.7 2 1 1 3 3 3 0 IncA protein Chibby PF14645.1 AEO68715.1 - 0.24 11.2 9.9 0.37 10.6 0.3 2.6 1 1 1 2 2 2 0 Chibby family CENP-F_leu_zip PF10473.4 AEO68715.1 - 1 9.2 35.4 0.19 11.5 13.9 3.7 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC144C PF14915.1 AEO68715.1 - 1.3 7.8 25.1 35 3.1 17.2 2.5 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region Filament PF00038.16 AEO68715.1 - 2.2 7.6 28.5 6.5 6.1 17.7 2.5 2 1 0 2 2 2 0 Intermediate filament protein IFT57 PF10498.4 AEO68715.1 - 4.8 5.8 17.9 0.1 11.3 5.4 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 CENP-H PF05837.7 AEO68715.1 - 5.1 7.3 18.0 1.4 9.1 3.0 3.3 1 1 2 3 3 3 0 Centromere protein H (CENP-H) ACC_central PF08326.7 AEO68716.1 - 1e-253 843.6 0.0 1.3e-253 843.3 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 AEO68716.1 - 1e-175 584.8 0.0 1.4e-175 584.4 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 AEO68716.1 - 3.5e-53 180.0 0.0 6.6e-53 179.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 AEO68716.1 - 1.1e-23 83.4 0.1 2.2e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 AEO68716.1 - 1.6e-21 76.3 0.0 1.4e-18 66.7 0.0 2.9 2 0 0 2 2 2 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 AEO68716.1 - 2.1e-15 56.0 0.1 4.8e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 AEO68716.1 - 1.6e-11 44.2 0.0 4.3e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AEO68716.1 - 1.1e-05 24.9 0.0 2.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 AEO68716.1 - 0.0023 17.8 0.0 0.0068 16.2 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 AEO68716.1 - 0.072 12.7 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 Biotin-lipoyl like BTB PF00651.26 AEO68718.1 - 7.9e-05 22.6 0.0 0.00024 21.0 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain SET PF00856.23 AEO68719.1 - 1e-08 35.6 0.1 1.7e-07 31.7 0.0 2.5 1 1 2 3 3 3 1 SET domain XRCC4 PF06632.7 AEO68719.1 - 0.54 9.0 2.5 0.6 8.8 0.1 1.9 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Ribosomal_L14 PF00238.14 AEO68720.1 - 3.2e-45 152.8 3.8 3.6e-45 152.6 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PUA PF01472.15 AEO68720.1 - 0.099 12.3 1.9 0.18 11.5 0.6 1.8 2 0 0 2 2 2 0 PUA domain TFIIS_C PF01096.13 AEO68721.1 - 5.7e-16 57.8 5.5 5.7e-16 57.8 3.8 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 AEO68721.1 - 1.2e-09 37.7 4.3 1.2e-09 37.7 3.0 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DUF2981 PF11200.3 AEO68721.1 - 0.064 12.3 0.0 0.077 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) C1_4 PF07975.7 AEO68721.1 - 0.24 11.4 13.5 0.58 10.2 1.2 2.8 2 1 1 3 3 3 0 TFIIH C1-like domain FAM163 PF15069.1 AEO68721.1 - 0.31 11.6 4.9 1.3 9.6 2.9 1.9 1 1 1 2 2 2 0 FAM163 family Lar_restr_allev PF14354.1 AEO68721.1 - 0.63 10.3 11.2 0.11 12.8 1.3 2.4 2 1 0 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.2 AEO68721.1 - 0.67 9.8 17.2 0.066 13.0 1.7 2.7 2 1 0 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.1 AEO68721.1 - 2.1 8.0 13.5 1.3 8.7 1.4 3.5 3 1 0 3 3 3 0 Nudix N-terminal zf-NADH-PPase PF09297.6 AEO68721.1 - 2.3 7.7 6.7 16 5.1 0.3 3.2 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain A2L_zn_ribbon PF08792.5 AEO68721.1 - 3.3 7.2 16.8 1 8.8 2.9 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain DUF2296 PF10058.4 AEO68721.1 - 3.6 7.4 11.5 3.6 7.4 0.4 3.0 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) IBR PF01485.16 AEO68721.1 - 4.3 7.2 14.5 1.6e+03 -1.0 10.1 2.7 1 1 0 1 1 1 0 IBR domain Zn_Tnp_IS1595 PF12760.2 AEO68721.1 - 7.3 6.4 15.5 1 9.1 4.0 3.0 2 2 0 2 2 2 0 Transposase zinc-ribbon domain GFA PF04828.9 AEO68721.1 - 7.6 6.5 14.1 0.56 10.1 0.7 2.7 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Rotamase PF00639.16 AEO68722.1 - 3e-22 79.1 0.0 4.1e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 AEO68722.1 - 1.7e-15 57.3 0.0 2.2e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 AEO68722.1 - 4.5e-08 32.8 1.3 9.4e-08 31.7 0.9 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 AEO68722.1 - 0.00011 22.8 0.0 0.00016 22.2 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain MAM PF00629.18 AEO68722.1 - 0.039 13.7 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 MAM domain LrgB PF04172.11 AEO68723.1 - 6.4e-13 48.3 0.7 1.2e-05 24.6 0.3 2.6 2 0 0 2 2 2 2 LrgB-like family Hemerythrin PF01814.18 AEO68724.1 - 0.041 14.0 8.4 2.3 8.3 0.2 4.4 4 2 0 4 4 4 0 Hemerythrin HHE cation binding domain Prefoldin_2 PF01920.15 AEO68724.1 - 0.18 11.5 5.4 3.6 7.3 1.5 3.5 3 1 0 3 3 3 0 Prefoldin subunit DUF948 PF06103.6 AEO68724.1 - 0.32 10.8 6.7 1.6 8.6 0.3 4.6 6 0 0 6 6 6 0 Bacterial protein of unknown function (DUF948) TBPIP PF07106.8 AEO68724.1 - 5.8 6.4 10.5 26 4.3 2.7 3.8 3 1 2 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Epimerase PF01370.16 AEO68725.1 - 1.1e-20 74.0 0.1 1.8e-20 73.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO68725.1 - 9.4e-14 51.8 0.5 1.2e-13 51.5 0.3 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 AEO68725.1 - 8.3e-10 37.8 0.0 1.1e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AEO68725.1 - 5.4e-08 32.0 0.3 1.3e-07 30.8 0.1 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 AEO68725.1 - 0.0001 21.3 0.1 0.0012 17.8 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein NmrA PF05368.8 AEO68725.1 - 0.0008 18.7 1.1 0.0019 17.5 0.8 1.6 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 AEO68725.1 - 0.0011 17.9 0.7 0.0028 16.5 0.5 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 AEO68725.1 - 0.0017 18.3 4.7 0.0035 17.2 2.1 2.2 2 1 0 2 2 2 1 short chain dehydrogenase DFP PF04127.10 AEO68725.1 - 0.013 15.0 0.1 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DapB_N PF01113.15 AEO68725.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 AEO68725.1 - 0.068 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF3894 PF13033.1 AEO68726.1 - 1.8 8.5 4.7 0.76 9.8 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3894) Mito_carr PF00153.22 AEO68728.1 - 2e-65 216.5 1.2 1.1e-22 79.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 AEO68729.1 - 5.4e-40 133.8 9.5 7.8e-10 38.2 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat F-box-like PF12937.2 AEO68729.1 - 7.2e-11 41.6 0.1 3.2e-10 39.5 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 AEO68729.1 - 4.9e-09 35.6 0.0 5.3e-08 32.3 0.0 2.4 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.3 AEO68729.1 - 1.3e-05 23.5 3.0 0.37 8.8 0.0 3.1 1 1 1 3 3 3 3 Nucleoporin Nup120/160 PRANC PF09372.5 AEO68729.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Abhydrolase_3 PF07859.8 AEO68730.1 - 6.9e-20 71.5 0.4 3.2e-18 66.0 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AEO68730.1 - 3.1e-13 49.4 0.0 5.6e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO68730.1 - 2.1e-07 30.7 0.0 4e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO68730.1 - 4.6e-07 29.9 10.2 1.2e-06 28.6 7.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO68730.1 - 0.0089 15.6 0.1 0.015 14.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 AEO68730.1 - 0.069 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_4 PF08386.5 AEO68730.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Acyl_transf_3 PF01757.17 AEO68731.1 - 1.7e-23 83.0 17.9 2.9e-23 82.2 12.4 1.5 1 1 0 1 1 1 1 Acyltransferase family F-box-like PF12937.2 AEO68733.1 - 7.3e-05 22.4 2.7 0.00036 20.1 0.1 2.8 2 0 0 2 2 2 1 F-box-like HARE-HTH PF05066.8 AEO68734.1 - 0.056 13.7 0.0 0.097 13.0 0.0 1.3 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain FSH1 PF03959.8 AEO68735.1 - 1.3e-26 93.3 0.0 1.7e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 AEO68735.1 - 1.9e-10 41.0 2.4 9.1e-09 35.5 0.9 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO68735.1 - 3.9e-05 23.4 0.1 7.2e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 AEO68735.1 - 0.0012 18.3 0.2 0.012 15.0 0.1 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Nuc_sug_transp PF04142.10 AEO68736.1 - 4.1e-71 238.9 10.4 5.4e-71 238.5 7.2 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 AEO68736.1 - 2.4e-08 33.7 24.5 2.3e-07 30.5 3.4 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 AEO68736.1 - 4.2e-08 32.4 24.3 1.2e-06 27.7 9.7 1.6 1 1 1 2 2 2 2 UAA transporter family EmrE PF13536.1 AEO68736.1 - 3.1e-06 27.3 4.5 3.1e-06 27.3 3.2 2.7 3 0 0 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 AEO68736.1 - 1.2e-05 25.3 7.3 1.2e-05 25.3 5.0 3.0 2 2 0 2 2 2 1 EamA-like transporter family UPF0546 PF10639.4 AEO68736.1 - 0.55 10.0 7.0 0.57 10.0 0.6 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 Mito_morph_reg PF14972.1 AEO68736.1 - 1.6 8.0 5.3 4.3 6.7 0.6 2.3 2 0 0 2 2 2 0 Mitochondrial morphogenesis regulator PIG-L PF02585.12 AEO68737.1 - 2.6e-20 73.2 0.0 3.9e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Gly_transf_sug PF04488.10 AEO68738.1 - 1.2e-12 48.0 0.0 2.2e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif UPF0154 PF03672.8 AEO68738.1 - 0.17 11.4 0.5 0.4 10.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Tautomerase_3 PF14832.1 AEO68740.1 - 1.1e-47 161.4 0.0 1.2e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 AEO68740.1 - 0.00031 20.2 0.0 0.00088 18.8 0.0 1.8 2 0 0 2 2 2 1 Tautomerase enzyme WSC PF01822.14 AEO68742.1 - 3.3e-15 55.7 12.2 3.8e-15 55.5 8.5 1.1 1 0 0 1 1 1 1 WSC domain Toxin_34 PF08396.5 AEO68742.1 - 0.74 10.4 8.3 1.5 9.4 5.7 1.5 1 1 0 1 1 1 0 Spider toxin omega agatoxin/Tx1 family Tme5_EGF_like PF09064.5 AEO68742.1 - 1.1 8.9 7.9 2.7 7.6 1.6 2.4 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like Pectate_lyase_3 PF12708.2 AEO68743.1 - 1.3e-22 81.0 6.3 6.1e-17 62.4 0.2 3.6 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 AEO68743.1 - 0.0042 16.5 0.1 0.013 14.9 0.0 1.9 1 0 0 1 1 1 1 N terminal extension of bacteriophage endosialidase DUF1077 PF06417.7 AEO68744.1 - 5e-45 151.8 4.6 1.7e-44 150.2 3.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1077) EcKinase PF02958.15 AEO68746.1 - 4.1e-18 65.5 0.0 1.9e-17 63.3 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 AEO68746.1 - 3.8e-12 46.4 0.2 8.6e-12 45.3 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 AEO68746.1 - 1.4e-06 27.2 0.0 3.7e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) ATP_transf PF09830.4 AEO68748.1 - 2.4e-16 59.2 0.0 4.6e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase LAT PF15234.1 AEO68748.1 - 0.21 11.0 2.6 2.9 7.2 0.3 2.3 2 0 0 2 2 2 0 Linker for activation of T-cells Scs3p PF10261.4 AEO68749.1 - 4.4e-67 225.5 0.4 5.9e-67 225.1 0.3 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 AEO68749.1 - 0.013 15.1 2.7 0.019 14.6 0.0 2.3 1 1 0 2 2 2 0 PAP2 superfamily Pectate_lyase_3 PF12708.2 AEO68750.1 - 1.9e-89 299.6 23.8 7e-71 238.9 8.8 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 AEO68750.1 - 6.5e-07 28.7 3.2 0.0064 15.9 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Sperm_Ag_HE2 PF05324.8 AEO68751.1 - 0.033 14.0 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 Sperm antigen HE2 WD40 PF00400.27 AEO68752.1 - 1.9e-42 141.6 15.9 1e-09 37.8 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 AEO68752.1 - 5.2e-11 42.0 0.2 1.2e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO68752.1 - 2.2e-07 30.3 0.2 5.4e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 AEO68752.1 - 1.9e-05 22.9 2.7 0.41 8.7 0.0 4.0 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AEO68752.1 - 0.00013 20.9 0.0 0.14 10.8 0.0 2.6 2 1 0 2 2 2 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 AEO68752.1 - 0.0057 14.9 0.0 0.011 14.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 AEO68752.1 - 0.024 14.1 0.1 0.073 12.5 0.1 1.6 1 1 0 1 1 1 0 PQQ-like domain FlaG PF03646.10 AEO68752.1 - 0.14 12.3 0.0 1.4 9.1 0.0 2.6 4 0 0 4 4 4 0 FlaG protein Glyco_transf_25 PF01755.12 AEO68754.1 - 1.3e-11 44.4 0.0 5e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF1610 PF07754.6 AEO68756.1 - 0.47 10.6 0.1 0.47 10.6 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1610) MFS_1 PF07690.11 AEO68758.1 - 3.6e-35 121.3 26.1 3.6e-35 121.3 18.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO68758.1 - 2.4e-11 42.8 18.4 3.5e-11 42.3 12.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 AEO68758.1 - 0.0078 15.9 1.7 0.023 14.5 0.8 2.2 2 0 0 2 2 2 1 MFS_1 like family Nop14 PF04147.7 AEO68759.1 - 0.15 9.9 12.1 0.25 9.2 8.4 1.3 1 0 0 1 1 1 0 Nop14-like family PBP_sp32 PF07222.7 AEO68759.1 - 0.16 11.1 4.1 0.28 10.3 2.9 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pox_Ag35 PF03286.9 AEO68759.1 - 0.68 9.4 19.2 0.021 14.3 6.5 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF3246 PF11596.3 AEO68759.1 - 1.6 7.9 4.7 0.22 10.7 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) PBP1_TM PF14812.1 AEO68759.1 - 2.8 8.3 26.8 0.19 12.0 3.2 3.0 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC27 PF09507.5 AEO68759.1 - 2.8 7.0 25.2 0.31 10.2 7.2 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 PGA2 PF07543.7 AEO68759.1 - 5.1 6.8 14.9 2.3 7.9 8.1 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF397 PF04149.7 AEO68760.1 - 0.081 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF397) F-box-like PF12937.2 AEO68761.1 - 0.0081 15.8 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like Plasmod_dom_1 PF09715.5 AEO68762.1 - 0.18 11.7 2.5 0.3 11.0 0.4 2.3 1 1 1 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) Glyco_hydro_61 PF03443.9 AEO68763.1 - 1.5e-56 191.7 0.1 2.4e-56 190.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 OmdA PF13376.1 AEO68764.1 - 4.6e-23 80.6 0.9 4.6e-23 80.6 0.7 1.9 2 0 0 2 2 2 1 Bacteriocin-protection, YdeI or OmpD-Associated Zn_clus PF00172.13 AEO68765.1 - 2.6e-08 33.6 5.3 4.1e-08 33.0 3.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO68766.1 - 3.4e-15 55.6 0.4 3.9e-15 55.4 0.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4131 PF13567.1 AEO68766.1 - 0.12 11.8 0.8 0.22 10.9 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Tom22 PF04281.8 AEO68767.1 - 1.4e-40 138.0 0.1 1.6e-40 137.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 PP2C PF00481.16 AEO68769.1 - 1.6e-61 207.9 0.1 3.5e-50 170.7 0.2 3.3 2 1 1 3 3 3 3 Protein phosphatase 2C Snf7 PF03357.16 AEO68770.1 - 4.1e-34 117.4 16.6 6.5e-34 116.7 11.5 1.3 1 0 0 1 1 1 1 Snf7 V_ATPase_I PF01496.14 AEO68770.1 - 0.0059 14.5 2.4 0.0072 14.2 1.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4309 PF14172.1 AEO68770.1 - 0.045 13.7 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) DFF40 PF09230.5 AEO68770.1 - 0.17 11.1 3.8 0.22 10.8 2.7 1.2 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa Ist1 PF03398.9 AEO68770.1 - 0.5 9.7 5.5 0.92 8.8 3.8 1.5 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway PspA_IM30 PF04012.7 AEO68770.1 - 0.62 9.3 15.3 0.26 10.6 2.1 2.2 1 1 0 2 2 2 0 PspA/IM30 family CaMBD PF02888.11 AEO68770.1 - 8.2 6.3 8.5 0.83 9.5 2.1 2.0 1 1 1 2 2 2 0 Calmodulin binding domain Dynamin_N PF00350.18 AEO68771.1 - 3.2e-17 62.8 0.9 6.1e-17 61.9 0.0 1.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 AEO68771.1 - 3.5e-09 36.6 0.1 1.4e-08 34.6 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AEO68771.1 - 4.2e-07 29.5 0.5 5.9e-06 25.8 0.4 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.8 AEO68771.1 - 0.0019 17.0 0.0 0.0037 16.1 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) PMEI PF04043.10 AEO68771.1 - 0.0083 16.0 0.2 0.032 14.1 0.1 2.0 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor SF-assemblin PF06705.6 AEO68771.1 - 0.02 14.0 0.9 0.049 12.7 0.6 1.7 1 0 0 1 1 1 0 SF-assemblin/beta giardin GvpK PF05121.7 AEO68771.1 - 0.033 14.0 1.0 1.4 8.7 0.0 3.2 3 0 0 3 3 3 0 Gas vesicle protein K PduV-EutP PF10662.4 AEO68771.1 - 0.033 13.6 0.0 6.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 AEO68771.1 - 0.062 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 AEO68771.1 - 0.063 13.5 0.1 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 AEO68772.1 - 7.2e-48 158.8 21.1 9.1e-10 38.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 AEO68772.1 - 3.2e-05 23.7 0.0 0.031 13.9 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cluap1 PF10234.4 AEO68772.1 - 0.1 11.7 0.9 0.14 11.3 0.6 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Cep57_CLD_2 PF14197.1 AEO68772.1 - 0.11 12.3 1.0 0.21 11.5 0.7 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 tRNA-synt_1c PF00749.16 AEO68773.1 - 2.6e-96 321.9 0.0 3.4e-96 321.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 AEO68773.1 - 2.2e-35 121.8 0.0 3.4e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 AEO68773.1 - 0.00013 21.2 0.1 0.00027 20.1 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain GST_C_3 PF14497.1 AEO68773.1 - 0.0007 20.0 0.0 0.0023 18.3 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Phosducin PF02114.11 AEO68774.1 - 3.9e-11 42.1 0.0 9.5e-10 37.6 0.0 2.3 2 1 0 2 2 2 2 Phosducin Ran_BP1 PF00638.13 AEO68776.1 - 3.8e-47 159.3 0.9 7.7e-47 158.3 0.6 1.5 1 0 0 1 1 1 1 RanBP1 domain YEATS PF03366.11 AEO68776.1 - 2.3e-23 81.6 0.1 5.7e-23 80.4 0.1 1.7 1 0 0 1 1 1 1 YEATS family PS-DH PF14765.1 AEO68776.1 - 0.028 13.5 0.6 0.055 12.6 0.4 1.4 1 0 0 1 1 1 0 Polyketide synthase dehydratase Pox_P4A PF03395.9 AEO68778.1 - 0.15 9.5 1.9 0.17 9.4 1.3 1.0 1 0 0 1 1 1 0 Poxvirus P4A protein Zn_clus PF00172.13 AEO68782.1 - 6.1e-07 29.2 11.8 9.6e-07 28.6 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SHOCT PF09851.4 AEO68782.1 - 0.16 11.4 0.5 0.33 10.4 0.3 1.5 1 0 0 1 1 1 0 Short C-terminal domain AMP-binding PF00501.23 AEO68783.1 - 2.4e-43 148.1 0.0 2.9e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO68783.1 - 5.1e-06 27.3 0.5 6.2e-05 23.8 0.0 2.7 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain TGF_beta_GS PF08515.7 AEO68783.1 - 4.1 6.8 6.7 9.1 5.7 4.6 1.6 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Aminotran_1_2 PF00155.16 AEO68784.1 - 2.2e-59 201.2 0.0 2.8e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AEO68784.1 - 0.0014 17.8 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 AEO68784.1 - 0.0087 14.8 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF4211 PF13926.1 AEO68785.1 - 5.3e-30 103.8 0.6 2.2e-29 101.8 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) AF-4 PF05110.8 AEO68785.1 - 0.0043 15.0 20.1 0.0043 15.0 13.9 2.9 2 1 1 3 3 3 1 AF-4 proto-oncoprotein Ebola_NP PF05505.7 AEO68785.1 - 5.2 4.9 31.7 0.34 8.9 13.2 2.1 2 0 0 2 2 2 0 Ebola nucleoprotein SAM_2 PF07647.12 AEO68786.1 - 2e-16 59.5 0.0 4.1e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 AEO68786.1 - 1.6e-14 53.8 0.0 3.1e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 AEO68786.1 - 5.2e-14 52.5 0.0 1.1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain CAF-1_p150 PF11600.3 AEO68788.1 - 0.00063 19.1 11.3 0.001 18.4 7.9 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 AEO68788.1 - 5.9 6.7 9.2 8.9 6.1 6.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_S13 PF00416.17 AEO68789.1 - 2.9e-41 140.2 1.5 3.5e-41 139.9 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 AEO68789.1 - 0.0046 15.5 0.0 0.005 15.4 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 AEO68789.1 - 0.052 13.5 0.3 0.17 11.9 0.1 1.9 2 1 0 2 2 2 0 Helix-hairpin-helix motif SBDS_C PF09377.5 AEO68790.1 - 6.4e-52 174.4 0.2 1e-51 173.8 0.1 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 AEO68790.1 - 1.1e-29 102.0 0.1 1.8e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein TFIIA PF03153.8 AEO68790.1 - 0.01 15.7 18.5 0.013 15.3 12.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Menin PF05053.8 AEO68790.1 - 0.049 11.7 7.8 0.06 11.5 5.4 1.1 1 0 0 1 1 1 0 Menin Hid1 PF12722.2 AEO68790.1 - 0.18 9.4 3.1 0.22 9.1 2.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pex16 PF08610.5 AEO68790.1 - 0.44 9.4 4.1 1.2 8.0 2.6 1.8 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) PAT1 PF09770.4 AEO68790.1 - 1.1 7.4 16.3 1.3 7.1 11.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1840 PF08895.6 AEO68790.1 - 1.4 8.9 5.3 9.5 6.2 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) DUF4557 PF15101.1 AEO68790.1 - 4.8 6.9 8.3 0.98 9.2 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Peptidase_S10 PF00450.17 AEO68791.1 - 2.6e-130 435.3 0.8 3.2e-130 435.0 0.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 AEO68791.1 - 4.2e-05 23.5 0.1 0.00082 19.3 0.0 2.7 3 0 0 3 3 3 1 Alpha/beta hydrolase family Carbpep_Y_N PF05388.6 AEO68791.1 - 5.6e-05 23.2 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide PDEase_I PF00233.14 AEO68792.1 - 5e-47 160.6 1.6 3e-44 151.5 0.1 2.1 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase UCH PF00443.24 AEO68793.1 - 1.9e-73 246.9 0.0 3.1e-72 242.9 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO68793.1 - 1.5e-15 57.4 0.0 1e-07 31.7 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 AEO68793.1 - 8.2e-11 42.1 0.0 1.9e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 DUSP domain zf-FPG_IleRS PF06827.9 AEO68793.1 - 0.15 11.7 0.9 5.2 6.8 0.1 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Peptidase_M16_C PF05193.16 AEO68794.1 - 7e-38 130.1 0.1 2.3e-20 73.0 0.0 3.5 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AEO68794.1 - 9.1e-32 109.8 3.8 1.2e-31 109.4 0.2 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Period_C PF12114.3 AEO68795.1 - 0.82 9.2 3.0 1.1 8.7 2.1 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region zf-CHCC PF10276.4 AEO68796.1 - 1.4e-15 56.7 0.7 2.1e-15 56.2 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 AEO68796.1 - 0.01 15.4 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb Methyltransf_18 PF12847.2 AEO68799.1 - 6.4e-19 68.5 0.1 9.7e-19 68.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO68799.1 - 7.5e-12 45.0 0.0 1.5e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 AEO68799.1 - 1.7e-09 37.7 0.3 5.9e-09 35.9 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO68799.1 - 1.3e-07 31.9 0.0 8.8e-07 29.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO68799.1 - 3e-07 30.3 0.3 2e-06 27.5 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO68799.1 - 1e-06 29.1 0.4 4.7e-05 23.8 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO68799.1 - 1e-06 29.0 0.0 4.1e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 AEO68799.1 - 0.00015 21.5 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 AEO68799.1 - 0.00087 18.7 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 AEO68799.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain AdoMet_MTase PF07757.8 AEO68799.1 - 0.004 17.2 0.0 0.0071 16.4 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_4 PF02390.12 AEO68799.1 - 0.081 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 AEO68799.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 AEO68799.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Pox_MCEL PF03291.11 AEO68799.1 - 0.13 11.1 0.0 0.35 9.6 0.0 1.6 2 0 0 2 2 2 0 mRNA capping enzyme HEAT PF02985.17 AEO68800.1 - 9.9e-46 149.7 14.0 0.0091 16.0 0.0 13.2 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 AEO68800.1 - 2e-31 108.1 3.5 9.4e-07 29.0 0.0 7.6 3 3 4 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.2 AEO68800.1 - 9.9e-12 45.1 2.6 0.045 14.1 0.0 7.5 5 2 4 9 9 8 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 AEO68800.1 - 2.4e-10 40.5 14.3 0.14 12.7 0.0 9.8 7 3 5 12 12 12 2 HEAT-like repeat Adaptin_N PF01602.15 AEO68800.1 - 4e-09 35.3 7.0 0.00012 20.6 0.1 5.1 3 2 1 5 5 5 3 Adaptin N terminal region CLASP_N PF12348.3 AEO68800.1 - 1.5e-06 27.7 1.4 0.36 10.1 0.0 5.0 3 2 1 4 4 4 2 CLASP N terminal DUF2435 PF10363.4 AEO68800.1 - 0.00016 21.4 3.8 0.13 12.1 0.1 4.4 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Cnd3 PF12719.2 AEO68800.1 - 0.0018 17.3 0.3 0.029 13.3 0.1 2.7 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 AEO68800.1 - 0.0027 17.4 4.6 1.5 8.7 0.0 5.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat DNA_alkylation PF08713.6 AEO68800.1 - 0.0067 15.9 0.0 5 6.5 0.0 3.6 3 1 1 4 4 4 1 DNA alkylation repair enzyme Cnd1 PF12717.2 AEO68800.1 - 0.0076 16.1 9.6 0.39 10.5 0.2 5.9 5 1 2 8 8 8 1 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.7 AEO68800.1 - 0.058 13.3 0.2 0.66 9.8 0.0 2.8 2 1 0 2 2 2 0 Exportin 1-like protein RIX1 PF08167.7 AEO68800.1 - 0.068 12.8 0.4 1.4 8.5 0.0 3.1 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Proteasom_PSMB PF10508.4 AEO68800.1 - 0.18 10.0 2.9 0.52 8.5 0.0 2.6 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit MMS19_N PF14500.1 AEO68800.1 - 0.28 10.4 3.3 1 8.5 0.1 3.2 4 0 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II Myotub-related PF06602.9 AEO68801.1 - 1.2e-129 432.1 0.0 1.6e-129 431.7 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 AEO68801.1 - 0.0057 16.9 0.0 0.02 15.1 0.0 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 AEO68801.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_S3_C PF00189.15 AEO68802.1 - 1.3e-16 60.5 0.1 2.6e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 AEO68802.1 - 2.5e-12 46.1 0.1 4.6e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 AEO68802.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mg_trans_NIPA PF05653.9 AEO68803.1 - 5.4e-99 330.9 11.7 6.8e-99 330.6 8.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 AEO68803.1 - 2.3e-09 37.4 1.6 2.3e-09 37.4 1.1 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 AEO68803.1 - 2.4e-05 24.3 8.6 2.4e-05 24.3 6.0 3.0 2 1 1 3 3 3 1 EamA-like transporter family DUF1282 PF06930.7 AEO68803.1 - 3 7.4 17.0 2.4 7.7 4.2 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF1282) Adap_comp_sub PF00928.16 AEO68805.1 - 3.9e-18 65.5 0.1 6e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AEO68805.1 - 2.5e-08 33.7 0.1 4.2e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2628 PF10947.3 AEO68806.1 - 0.36 10.6 3.2 0.42 10.4 2.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) Apc4 PF12896.2 AEO68807.1 - 3.8e-62 209.3 0.2 6.6e-62 208.5 0.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 PH PF00169.24 AEO68808.1 - 0.0019 18.3 0.0 0.0058 16.8 0.0 1.8 1 0 0 1 1 1 1 PH domain MgpC PF05220.7 AEO68810.1 - 0.063 12.3 0.8 0.13 11.3 0.6 1.5 1 0 0 1 1 1 0 MgpC protein precursor SoxE PF06525.6 AEO68810.1 - 0.067 12.4 0.6 0.12 11.6 0.4 1.3 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Adenylsucc_synt PF00709.16 AEO68811.1 - 7.3e-153 509.1 0.0 8.2e-153 509.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase ELO PF01151.13 AEO68812.1 - 2.9e-83 279.0 2.9 3.5e-83 278.7 2.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family FYVE PF01363.16 AEO68813.1 - 1.4e-15 56.9 7.0 2.3e-15 56.2 4.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 AEO68813.1 - 4.1 7.3 15.9 0.21 11.4 7.2 1.7 2 0 0 2 2 2 0 AN1-like Zinc finger Synaptobrevin PF00957.16 AEO68814.1 - 8.7e-15 54.0 0.4 1.4e-14 53.4 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 AEO68814.1 - 1.7e-13 49.9 0.0 3e-13 49.1 0.0 1.5 1 1 0 1 1 1 1 Regulated-SNARE-like domain TFR_dimer PF04253.10 AEO68814.1 - 0.023 14.2 0.1 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain EzrA PF06160.7 AEO68814.1 - 0.029 12.5 0.5 0.048 11.8 0.3 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4191 PF13829.1 AEO68814.1 - 0.029 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) MoaC PF01967.16 AEO68815.1 - 3.7e-48 162.6 4.8 6e-24 84.2 0.0 2.3 2 0 0 2 2 2 2 MoaC family Mob_synth_C PF06463.8 AEO68815.1 - 2.3e-34 117.8 0.0 6.3e-34 116.4 0.0 1.7 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 AEO68815.1 - 3.7e-18 66.2 0.0 6.3e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 AEO68815.1 - 0.00015 21.8 0.0 0.00038 20.5 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 AEO68815.1 - 0.0003 20.7 0.0 0.0022 17.9 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Vps16_N PF04841.8 AEO68816.1 - 0.094 11.2 0.0 0.39 9.1 0.0 1.9 2 0 0 2 2 2 0 Vps16, N-terminal region IKI3 PF04762.7 AEO68816.1 - 0.14 9.9 0.0 5.6 4.6 0.0 2.6 2 1 0 2 2 2 0 IKI3 family RRM_1 PF00076.17 AEO68817.1 - 2.2e-12 46.4 0.0 1.4e-08 34.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO68817.1 - 8e-11 41.7 0.0 1e-07 31.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO68817.1 - 0.00039 20.2 0.0 0.00064 19.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3535 PF12054.3 AEO68818.1 - 4.4e-152 506.7 0.1 4.6e-151 503.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 AEO68818.1 - 1.4e-73 247.2 0.0 2.1e-73 246.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 AEO68818.1 - 1.1e-14 53.0 9.9 0.0072 16.3 0.0 9.8 10 0 0 10 10 10 4 HEAT repeat Helicase_C PF00271.26 AEO68818.1 - 2.8e-14 52.7 0.0 7.1e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_EZ PF13513.1 AEO68818.1 - 2.1e-06 28.0 7.2 13 6.4 0.0 8.4 7 0 0 7 7 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 AEO68818.1 - 2.2e-06 27.9 0.8 0.19 12.1 0.0 4.0 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 AEO68818.1 - 3.6e-06 27.1 16.5 0.011 15.9 0.0 7.3 7 2 1 8 8 8 1 HEAT repeats CLASP_N PF12348.3 AEO68818.1 - 0.017 14.4 0.3 4.3 6.6 0.1 3.0 3 0 0 3 3 3 0 CLASP N terminal SMC_N PF02463.14 AEO68819.1 - 1.3e-65 220.6 2.9 2.1e-65 220.0 2.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AEO68819.1 - 1e-25 90.0 0.4 5.3e-25 87.7 0.0 2.6 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 AEO68819.1 - 8.3e-16 58.7 1.6 3.4e-07 30.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 AEO68819.1 - 5.7e-08 33.3 47.3 5.7e-08 33.3 32.8 7.2 2 2 2 5 5 5 1 AAA domain AAA_15 PF13175.1 AEO68819.1 - 1.3e-06 27.7 31.0 3.4e-05 23.0 6.0 3.7 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 AEO68819.1 - 0.00042 19.7 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 AEO68819.1 - 0.35 11.1 0.0 0.35 11.1 0.0 6.7 3 2 0 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 AEO68819.1 - 1.4 8.0 28.0 0.35 9.9 1.8 4.8 3 2 1 5 5 5 0 Reovirus sigma C capsid protein CDC37_N PF03234.9 AEO68820.1 - 4.3e-59 199.7 5.1 4.3e-59 199.7 3.5 2.6 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 AEO68820.1 - 4.4e-46 156.5 0.0 1.5e-45 154.8 0.0 1.8 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 AEO68820.1 - 1e-26 92.6 2.2 1e-26 92.6 1.5 2.6 2 0 0 2 2 2 1 Cdc37 C terminal domain CR6_interact PF10147.4 AEO68820.1 - 0.017 14.4 0.8 0.017 14.4 0.5 2.1 3 0 0 3 3 3 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF1268 PF06896.6 AEO68820.1 - 0.037 14.3 0.3 0.037 14.3 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1268) DUF948 PF06103.6 AEO68820.1 - 0.12 12.2 1.0 0.39 10.6 0.7 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2762 PF10960.3 AEO68820.1 - 0.33 10.6 7.3 0.078 12.6 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2762) Striatin PF08232.7 AEO68820.1 - 0.33 11.2 9.1 0.21 11.9 0.4 2.9 3 0 0 3 3 3 0 Striatin family DUF155 PF02582.9 AEO68822.1 - 4.6e-55 186.2 0.3 6.4e-55 185.7 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 HMG_box PF00505.14 AEO68823.1 - 7.5e-09 35.7 0.3 3.4e-08 33.6 0.2 2.1 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AEO68823.1 - 4.9e-06 26.8 1.0 1.2e-05 25.5 0.2 2.1 2 0 0 2 2 2 1 HMG-box domain DUF3987 PF13148.1 AEO68823.1 - 0.43 9.0 11.5 0.02 13.4 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Cpn60_TCP1 PF00118.19 AEO68824.1 - 2.5e-138 461.7 6.2 2.8e-138 461.5 4.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PP1_inhibitor PF05361.7 AEO68824.1 - 0.0012 18.5 1.1 0.0038 16.9 0.6 1.9 1 1 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor Y_phosphatase3 PF13350.1 AEO68824.1 - 0.031 14.5 0.3 0.34 11.1 0.0 2.3 2 0 0 2 2 2 0 Tyrosine phosphatase family Nitro_FeMo-Co PF02579.12 AEO68824.1 - 0.071 13.1 0.0 0.38 10.8 0.0 2.3 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor PH_10 PF15411.1 AEO68827.1 - 7.5e-28 97.0 0.2 1.2e-27 96.4 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 AEO68827.1 - 9.5e-08 31.7 6.3 1.6e-07 31.0 4.3 1.4 1 0 0 1 1 1 1 Ring finger domain VWA_3 PF13768.1 AEO68827.1 - 5.5e-05 22.9 0.1 0.00011 21.8 0.1 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 AEO68827.1 - 0.00026 20.7 0.1 0.00043 20.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_5 PF14634.1 AEO68827.1 - 0.00076 19.1 5.7 0.0013 18.4 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 AEO68827.1 - 0.00089 18.8 2.7 0.0015 18.1 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO68827.1 - 0.0012 18.9 1.0 0.0025 17.8 0.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AEO68827.1 - 0.0075 16.2 5.2 0.014 15.4 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO68827.1 - 0.011 15.3 5.8 0.022 14.3 4.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C4_Topoisom PF01396.14 AEO68827.1 - 0.087 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger zf-RING-like PF08746.6 AEO68827.1 - 0.091 12.7 4.9 0.17 11.9 3.4 1.5 1 0 0 1 1 1 0 RING-like domain zf-UDP PF14569.1 AEO68827.1 - 0.11 12.1 0.8 0.27 11.0 0.5 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF4093 PF13331.1 AEO68827.1 - 0.12 12.6 0.7 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4093) DUF1272 PF06906.6 AEO68827.1 - 3.3 7.6 5.5 8 6.4 3.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) MFS_1 PF07690.11 AEO68829.1 - 4.7e-23 81.4 36.6 1.3e-22 80.0 25.0 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily INTS5_C PF14838.1 AEO68829.1 - 0.073 11.3 0.4 0.11 10.7 0.3 1.1 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus Saccharop_dh PF03435.13 AEO68830.1 - 7e-18 64.7 0.0 8.6e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 AEO68830.1 - 0.0071 16.6 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 AEO68830.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L37ae PF01780.14 AEO68831.1 - 3.8e-39 132.4 8.0 4.2e-39 132.3 5.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 AEO68831.1 - 0.005 16.6 3.3 0.0075 16.0 2.3 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 AEO68831.1 - 0.043 13.2 2.8 1.8 8.1 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 AEO68831.1 - 0.053 13.4 2.1 0.35 10.8 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1364 PF07102.7 AEO68831.1 - 0.064 13.1 0.6 0.093 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) NCD3G PF07562.9 AEO68831.1 - 0.088 12.5 1.2 0.14 11.9 0.8 1.3 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR OrfB_Zn_ribbon PF07282.6 AEO68831.1 - 0.088 12.4 1.3 0.13 11.9 0.9 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Sgf11 PF08209.6 AEO68831.1 - 0.11 11.8 0.8 0.73 9.1 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Elf1 PF05129.8 AEO68831.1 - 0.12 12.0 3.3 0.24 11.1 2.3 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Tnp_zf-ribbon_2 PF13842.1 AEO68831.1 - 0.15 12.4 3.1 0.39 11.1 1.9 1.9 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-BED PF02892.10 AEO68831.1 - 0.17 11.6 5.6 3.7 7.3 0.3 2.3 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.1 AEO68831.1 - 0.19 12.0 2.0 1.6 9.1 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 AEO68831.1 - 0.3 11.5 3.7 1.9 8.9 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-RING_2 PF13639.1 AEO68832.1 - 5.6e-10 38.8 18.8 9e-09 35.0 1.2 4.1 4 0 0 4 4 4 2 Ring finger domain PHD PF00628.24 AEO68832.1 - 2.5e-09 36.6 5.2 2.5e-09 36.6 3.6 2.7 2 1 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.2 AEO68832.1 - 2.1e-08 34.1 10.1 0.00015 21.7 3.8 3.2 2 1 0 2 2 2 2 RING-H2 zinc finger zf-Apc11 PF12861.2 AEO68832.1 - 2.7e-07 30.3 8.0 0.0012 18.6 1.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 AEO68832.1 - 2.8e-05 23.7 1.3 2.8e-05 23.7 0.9 3.4 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO68832.1 - 0.00015 21.7 1.0 0.00015 21.7 0.7 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO68832.1 - 0.00017 21.1 2.1 0.00017 21.1 1.4 3.5 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO68832.1 - 0.00034 20.2 1.0 0.00034 20.2 0.7 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 AEO68832.1 - 0.00042 19.5 2.3 0.00042 19.5 1.6 2.0 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 AEO68832.1 - 0.0017 18.0 1.5 0.0017 18.0 1.0 3.1 3 1 0 3 3 3 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 AEO68832.1 - 0.23 10.7 6.2 0.042 13.1 0.9 2.1 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_4 PF14570.1 AEO68832.1 - 0.3 10.6 3.9 0.32 10.6 0.5 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 AEO68832.1 - 0.81 9.6 7.9 0.094 12.6 0.3 2.5 2 0 0 2 2 2 0 FANCL C-terminal domain MRP-L46 PF11788.3 AEO68833.1 - 1.4e-30 106.1 0.1 2.3e-30 105.4 0.1 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 AEO68833.1 - 0.00032 20.3 0.3 0.00065 19.3 0.2 1.4 1 0 0 1 1 1 1 NUDIX domain CAF1 PF04857.15 AEO68834.1 - 6.3e-41 140.4 0.0 1.3e-40 139.3 0.0 1.5 1 1 0 1 1 1 1 CAF1 family ribonuclease RNase_T PF00929.19 AEO68834.1 - 0.17 12.1 0.0 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Exonuclease DUF3716 PF12511.3 AEO68835.1 - 0.00098 18.6 3.3 0.0019 17.7 2.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) TCL1_MTCP1 PF01840.12 AEO68835.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 TCL1/MTCP1 family HMG14_17 PF01101.13 AEO68837.1 - 2 9.1 9.9 3.3 8.4 6.9 1.4 1 0 0 1 1 1 0 HMG14 and HMG17 Cytochrom_B561 PF03188.11 AEO68840.1 - 1.6e-07 31.2 6.1 3e-07 30.3 4.2 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2076 PF09849.4 AEO68840.1 - 0.035 14.1 0.0 0.035 14.1 0.0 3.1 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2427 PF10348.4 AEO68840.1 - 0.07 12.7 3.3 0.16 11.5 2.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF1183 PF06682.7 AEO68840.1 - 0.16 11.5 11.1 1.1 8.8 3.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) Nnf1 PF03980.9 AEO68841.1 - 3.1e-30 104.3 1.5 5.7e-30 103.5 0.0 2.2 3 0 0 3 3 3 1 Nnf1 DUF948 PF06103.6 AEO68841.1 - 0.061 13.1 0.2 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) HAUS-augmin3 PF14932.1 AEO68841.1 - 0.12 11.5 1.4 0.2 10.8 1.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 PH_9 PF15410.1 AEO68842.1 - 2.7e-09 37.2 0.0 4.1e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain YonK PF09642.5 AEO68842.1 - 0.096 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 YonK protein PH PF00169.24 AEO68842.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 PH domain NTF2 PF02136.15 AEO68843.1 - 7.3e-25 87.6 0.1 1.2e-24 86.9 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 AEO68843.1 - 1.7e-08 33.9 0.1 2.7e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO68843.1 - 4.5e-06 26.5 0.2 9.7e-06 25.4 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AEO68843.1 - 0.00031 20.5 0.1 0.00094 18.9 0.0 1.8 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.1 AEO68843.1 - 0.00058 19.6 0.1 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.6 AEO68843.1 - 3 8.3 17.4 10 6.6 12.0 1.9 1 0 0 1 1 1 0 Glycine rich protein family Acyltransferase PF01553.16 AEO68845.1 - 4.4e-14 52.0 0.0 7.9e-14 51.2 0.0 1.4 1 1 0 1 1 1 1 Acyltransferase zf-C3HC4_2 PF13923.1 AEO68846.1 - 4.3e-09 36.2 15.7 1.7e-05 24.7 4.1 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO68846.1 - 1.8e-06 27.5 5.6 1.8e-06 27.5 3.9 3.0 2 2 1 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 AEO68846.1 - 2.9e-06 26.9 14.5 1.4e-05 24.7 2.7 2.8 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_3 PF13920.1 AEO68846.1 - 3.8e-06 26.4 13.5 1.2e-05 24.8 3.5 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO68846.1 - 1.4e-05 24.6 17.1 0.00044 19.8 3.0 2.8 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AEO68846.1 - 6.2e-05 22.6 1.0 6.2e-05 22.6 0.7 3.0 2 1 1 3 3 3 1 RING-type zinc-finger Rtf2 PF04641.7 AEO68846.1 - 8.1e-05 21.9 1.2 8.1e-05 21.9 0.8 2.8 2 1 1 3 3 3 1 Rtf2 RING-finger FYVE PF01363.16 AEO68846.1 - 0.0001 22.1 7.7 0.00037 20.3 1.3 2.7 2 0 0 2 2 2 1 FYVE zinc finger zf-C3HC4_4 PF15227.1 AEO68846.1 - 0.00029 20.6 14.9 0.001 18.9 3.9 2.7 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-TFIIIC PF12660.2 AEO68846.1 - 0.014 15.3 4.3 1.5 8.7 0.1 2.4 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex zinc-ribbons_6 PF07191.7 AEO68846.1 - 2.8 7.7 11.4 17 5.2 3.6 3.0 2 1 0 2 2 2 0 zinc-ribbons SCA7 PF08313.7 AEO68847.1 - 6e-33 112.2 0.5 1.6e-32 110.8 0.3 1.7 1 0 0 1 1 1 1 SCA7, zinc-binding domain DUF3128 PF11326.3 AEO68847.1 - 0.52 10.4 3.1 1.4 9.0 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) CDC45 PF02724.9 AEO68847.1 - 1.6 6.6 9.1 2.2 6.1 6.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3505 PF12013.3 AEO68847.1 - 7.2 6.8 8.1 5.1 7.3 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) DUF2457 PF10446.4 AEO68847.1 - 8.3 5.0 23.2 0.28 9.8 10.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Pkinase PF00069.20 AEO68848.1 - 6.4e-76 254.9 0.0 8.1e-76 254.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Peptidase_M28 PF04389.12 AEO68848.1 - 4.9e-40 137.1 0.0 8.4e-40 136.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Pkinase_Tyr PF07714.12 AEO68848.1 - 1.9e-37 128.7 0.0 2.7e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO68848.1 - 0.033 13.1 0.0 0.073 12.0 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.9 AEO68848.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAXIP1_C PF15364.1 AEO68849.1 - 1 9.2 5.3 3 7.7 3.7 1.8 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Dynamin_N PF00350.18 AEO68853.1 - 3.9e-16 59.3 0.0 6.4e-15 55.3 0.0 2.9 1 1 1 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 AEO68853.1 - 6.3e-05 22.9 0.0 0.02 14.8 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 AEO68853.1 - 0.0019 18.4 0.7 0.019 15.2 0.0 2.6 2 0 0 2 2 2 1 ABC transporter DUF4618 PF15397.1 AEO68853.1 - 0.0038 16.5 9.7 0.021 14.2 1.3 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) Zeta_toxin PF06414.7 AEO68853.1 - 0.0045 16.1 0.0 0.014 14.5 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin DUF258 PF03193.11 AEO68853.1 - 0.0055 15.8 0.0 0.031 13.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 RasGAP_C PF03836.10 AEO68853.1 - 0.021 14.5 0.9 0.021 14.5 0.6 2.9 3 0 0 3 3 3 0 RasGAP C-terminus Miro PF08477.8 AEO68853.1 - 0.028 14.9 0.0 0.089 13.2 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein IIGP PF05049.8 AEO68853.1 - 0.038 12.7 1.2 0.089 11.5 0.1 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AIG1 PF04548.11 AEO68853.1 - 0.07 12.2 0.8 0.2 10.7 0.0 2.2 3 0 0 3 3 3 0 AIG1 family AAA_17 PF13207.1 AEO68853.1 - 0.08 13.7 0.0 1.5 9.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 AEO68853.1 - 0.094 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1664 PF07889.7 AEO68853.1 - 0.31 10.8 2.4 13 5.5 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.17 AEO68853.1 - 0.32 11.0 11.5 2.4 8.2 0.2 3.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.1 AEO68853.1 - 0.74 9.7 13.9 0.42 10.5 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 AEO68853.1 - 1 9.0 18.6 0.34 10.6 0.2 3.6 4 0 0 4 4 3 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 AEO68853.1 - 1.4 8.5 25.3 1.6 8.2 3.7 3.0 1 1 1 2 2 2 0 IncA protein DivIC PF04977.10 AEO68853.1 - 1.5 8.3 11.9 1.4 8.4 1.9 2.9 2 0 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 AEO68853.1 - 4.9 7.0 17.7 0.22 11.3 2.0 3.3 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding AATF-Che1 PF13339.1 AEO68853.1 - 6.8 6.8 13.6 3.6 7.7 2.3 3.3 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor NUDIX_2 PF13869.1 AEO68854.1 - 1.7e-81 272.0 0.0 2e-81 271.8 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF4316 PF14195.1 AEO68854.1 - 0.084 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) UPF0047 PF01894.12 AEO68855.1 - 1e-40 138.2 0.0 1.2e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 ABC_membrane PF00664.18 AEO68856.1 - 2e-81 273.4 24.0 1.8e-44 152.2 7.9 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AEO68856.1 - 7.7e-52 175.2 0.0 9.7e-30 103.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 AEO68856.1 - 2.2e-08 33.6 4.2 0.0055 15.9 0.0 4.3 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AEO68856.1 - 2.9e-05 24.1 0.6 0.099 12.6 0.1 3.3 4 0 0 4 4 2 2 AAA ATPase domain DUF258 PF03193.11 AEO68856.1 - 6.7e-05 22.1 0.1 0.073 12.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 AEO68856.1 - 7.3e-05 22.7 0.1 0.57 10.1 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 AEO68856.1 - 8.4e-05 22.0 0.0 0.045 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 AEO68856.1 - 0.00026 20.4 0.1 0.98 8.9 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 AEO68856.1 - 0.00035 21.0 0.3 0.99 9.9 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 AEO68856.1 - 0.00098 19.4 0.9 0.18 12.0 0.0 2.9 4 0 0 4 4 3 1 AAA domain AAA_21 PF13304.1 AEO68856.1 - 0.0017 18.3 0.1 2.1 8.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 AEO68856.1 - 0.0065 16.2 1.6 0.37 10.5 0.1 2.5 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 AEO68856.1 - 0.0074 15.7 0.0 3.4 7.0 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 AEO68856.1 - 0.019 14.8 0.5 0.81 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_30 PF13604.1 AEO68856.1 - 0.021 14.3 0.7 5.3 6.5 0.0 3.4 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 AEO68856.1 - 0.057 13.0 0.2 0.36 10.4 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 AEO68856.1 - 0.087 13.6 0.1 5.4 7.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 AEO68856.1 - 0.11 12.6 0.8 15 5.6 0.0 3.1 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 AEO68856.1 - 0.14 11.2 0.0 7.9 5.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AIG1 PF04548.11 AEO68856.1 - 0.48 9.5 1.5 6.6 5.7 0.0 2.3 2 0 0 2 2 2 0 AIG1 family DUF2841 PF11001.3 AEO68857.1 - 4.5e-37 126.7 2.8 8.5e-37 125.8 1.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF3243 PF11588.3 AEO68857.1 - 0.0072 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3243) DUF2431 PF10354.4 AEO68858.1 - 1e-52 178.4 0.0 1.4e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Methyltransf_26 PF13659.1 AEO68858.1 - 0.0006 19.8 0.0 0.0016 18.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Sds3 PF08598.6 AEO68859.1 - 4.8e-05 22.9 1.6 4.8e-05 22.9 1.1 1.8 2 0 0 2 2 2 1 Sds3-like ThiF PF00899.16 AEO68860.1 - 2.6e-13 49.9 0.0 2.6e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 ThiF family Cornichon PF03311.9 AEO68860.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Cornichon protein eIF-6 PF01912.13 AEO68862.1 - 3.7e-82 274.2 0.8 4.7e-82 273.8 0.5 1.1 1 0 0 1 1 1 1 eIF-6 family Nop14 PF04147.7 AEO68863.1 - 0.17 9.7 12.7 0.28 9.0 8.8 1.3 1 0 0 1 1 1 0 Nop14-like family PBP_sp32 PF07222.7 AEO68863.1 - 0.18 10.9 4.7 0.32 10.1 3.3 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pox_Ag35 PF03286.9 AEO68863.1 - 0.7 9.3 18.8 0.022 14.2 6.3 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CDC27 PF09507.5 AEO68863.1 - 0.83 8.8 23.3 0.13 11.4 6.3 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 PBP1_TM PF14812.1 AEO68863.1 - 3.5 8.0 27.3 0.32 11.3 3.7 3.0 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PGA2 PF07543.7 AEO68863.1 - 5.2 6.8 15.4 2.4 7.9 8.5 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 Fib_alpha PF08702.5 AEO68864.1 - 0.14 12.2 0.8 0.38 10.8 0.3 1.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2570 PF10828.3 AEO68864.1 - 0.43 10.1 3.7 1.3 8.6 2.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Spc7 PF08317.6 AEO68864.1 - 0.58 8.7 4.5 0.96 8.0 3.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.1 AEO68864.1 - 1.2 8.3 6.0 1.7 7.7 4.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4527 PF15030.1 AEO68864.1 - 1.2 8.3 8.7 0.067 12.5 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4527) FUSC PF04632.7 AEO68864.1 - 1.5 7.1 13.1 2.3 6.5 9.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family IncA PF04156.9 AEO68864.1 - 2.4 7.6 9.8 5.3 6.5 6.8 1.5 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 AEO68864.1 - 3.6 6.4 7.5 6.8 5.5 5.2 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 AEO68864.1 - 7.7 5.4 6.4 11 4.8 4.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 NDUF_B12 PF08122.7 AEO68865.1 - 2.3e-16 59.2 2.1 4.2e-16 58.4 1.4 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family CAF1 PF04857.15 AEO68866.1 - 4.9e-68 229.2 0.0 7.5e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease RFX_DNA_binding PF02257.10 AEO68866.1 - 0.063 13.4 0.3 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 RFX DNA-binding domain DUF3371 PF11851.3 AEO68866.1 - 2 9.1 14.4 7 7.3 3.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) FCP1_C PF09309.5 AEO68866.1 - 8.5 5.5 9.2 10 5.3 2.2 2.2 2 0 0 2 2 2 0 FCP1, C-terminal CLTH PF10607.4 AEO68867.1 - 1.2e-37 128.8 0.1 1.9e-37 128.1 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 AEO68867.1 - 0.039 13.7 0.0 0.09 12.5 0.0 1.7 1 0 0 1 1 1 0 LisH HLH PF00010.21 AEO68868.1 - 3.1e-12 45.9 0.2 6.6e-12 44.9 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DivIC PF04977.10 AEO68868.1 - 0.057 12.9 1.7 0.12 11.9 1.2 1.5 1 0 0 1 1 1 0 Septum formation initiator AAA_32 PF13654.1 AEO68868.1 - 0.084 11.5 2.1 0.13 10.9 1.4 1.2 1 0 0 1 1 1 0 AAA domain TSC22 PF01166.13 AEO68868.1 - 0.13 12.2 0.4 0.13 12.2 0.3 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family Pox_A30L_A26L PF06086.7 AEO68868.1 - 0.19 11.1 0.1 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein Aminotran_3 PF00202.16 AEO68869.1 - 1e-99 333.6 0.0 1.2e-99 333.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 AEO68869.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II SET PF00856.23 AEO68870.1 - 3.3e-22 79.5 0.1 3.3e-22 79.5 0.1 3.1 2 2 0 2 2 2 1 SET domain SRI PF08236.6 AEO68870.1 - 2.1e-21 75.6 5.1 4.1e-21 74.7 3.5 1.5 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.21 AEO68870.1 - 3.6e-06 26.7 1.8 7.1e-06 25.7 1.3 1.5 1 0 0 1 1 1 1 WW domain Med26 PF08711.6 AEO68870.1 - 0.01 15.3 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Terpene_synth PF01397.16 AEO68870.1 - 0.027 13.8 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain CENP-O PF09496.5 AEO68870.1 - 0.093 12.9 0.1 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component AT_hook PF02178.14 AEO68871.1 - 6.2 6.8 10.3 0.41 10.4 2.6 2.7 2 0 0 2 2 2 0 AT hook motif XPC-binding PF09280.6 AEO68873.1 - 3.6e-24 83.9 12.9 6.7e-24 83.1 8.9 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 AEO68873.1 - 2.5e-18 65.3 4.2 1.2e-08 34.5 0.2 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 AEO68873.1 - 8e-18 63.6 0.4 1.3e-17 62.9 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 AEO68873.1 - 7.7e-10 38.3 0.5 1.4e-09 37.5 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MCM_N PF14551.1 AEO68873.1 - 0.00018 21.9 0.1 0.00043 20.7 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain UBA_3 PF09288.5 AEO68873.1 - 0.0027 17.2 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain DUF2407 PF10302.4 AEO68873.1 - 0.007 16.5 0.0 0.015 15.4 0.0 1.6 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 AEO68873.1 - 0.038 13.8 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like FAP PF07174.6 AEO68873.1 - 2.6 7.2 33.5 2.4 7.3 13.9 2.1 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) RuvA_C PF07499.8 AEO68873.1 - 9.4 6.4 8.7 15 5.8 0.0 3.1 3 0 0 3 3 3 0 RuvA, C-terminal domain Myb_DNA-binding PF00249.26 AEO68874.1 - 9.8e-10 38.3 0.0 1.8e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO68874.1 - 0.0045 17.0 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain BRE1 PF08647.6 AEO68875.1 - 7.8e-29 99.5 7.0 7.8e-29 99.5 4.9 6.0 4 1 0 5 5 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 AEO68875.1 - 6.6e-09 35.6 8.8 1.1e-08 34.8 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO68875.1 - 7.4e-09 35.1 7.5 1.3e-08 34.3 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO68875.1 - 1.1e-07 31.4 9.3 2.1e-07 30.5 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AEO68875.1 - 3e-07 29.9 7.6 5.6e-07 29.1 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO68875.1 - 5.9e-07 29.2 7.3 1e-06 28.4 5.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 AEO68875.1 - 0.00016 21.2 4.3 0.00042 19.9 3.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 AEO68875.1 - 0.00032 20.4 4.9 0.00082 19.1 3.4 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 AEO68875.1 - 0.0012 18.3 2.7 0.0024 17.3 1.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C2H2_6 PF13912.1 AEO68875.1 - 0.0031 17.3 1.0 0.25 11.2 0.0 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C3HC4_4 PF15227.1 AEO68875.1 - 0.0034 17.2 6.0 0.0076 16.1 4.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Reo_sigmaC PF04582.7 AEO68875.1 - 0.0059 15.8 24.8 0.0059 15.8 1.5 4.2 2 1 1 4 4 4 3 Reovirus sigma C capsid protein zf-RING_4 PF14570.1 AEO68875.1 - 0.067 12.7 6.1 0.27 10.8 4.4 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C2H2 PF00096.21 AEO68875.1 - 0.1 12.9 0.1 0.1 12.9 0.1 3.2 4 0 0 4 4 3 0 Zinc finger, C2H2 type DUF1183 PF06682.7 AEO68876.1 - 2.7e-77 260.4 7.1 4.3e-77 259.8 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) ABC_membrane PF00664.18 AEO68877.1 - 7.1e-94 314.2 41.0 4.8e-47 160.6 11.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AEO68877.1 - 1.4e-67 226.1 0.1 3.4e-33 114.8 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 AEO68877.1 - 4.1e-13 49.0 0.0 0.00029 20.1 0.0 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AEO68877.1 - 1.1e-09 38.7 0.7 0.27 11.1 0.1 4.3 2 2 1 3 3 3 3 AAA domain AAA_29 PF13555.1 AEO68877.1 - 5.9e-09 35.3 1.4 0.00035 20.0 0.2 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 AEO68877.1 - 1.3e-07 30.6 3.1 0.0081 14.7 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 AEO68877.1 - 5.9e-07 30.3 0.0 0.079 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AEO68877.1 - 1.7e-06 28.1 7.2 0.00088 19.3 0.1 3.8 3 1 1 4 4 4 2 AAA ATPase domain DUF258 PF03193.11 AEO68877.1 - 1e-05 24.8 0.1 0.13 11.3 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 AEO68877.1 - 1.5e-05 24.4 0.3 0.2 11.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 AEO68877.1 - 0.00053 19.8 1.9 1.2 9.0 0.1 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 AEO68877.1 - 0.0013 18.8 3.8 2 8.5 0.2 4.0 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 AEO68877.1 - 0.0033 17.3 0.4 4.2 7.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.1 AEO68877.1 - 0.0033 17.3 0.0 2.5 8.0 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 AEO68877.1 - 0.0035 17.6 0.0 3.6 7.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 AEO68877.1 - 0.0044 16.9 0.5 0.7 9.8 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 AEO68877.1 - 0.0083 15.8 0.1 8.6 6.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 AEO68877.1 - 0.009 14.7 0.0 0.87 8.2 0.0 2.4 2 1 0 2 2 2 1 G-protein alpha subunit AAA_10 PF12846.2 AEO68877.1 - 0.017 14.5 3.2 12 5.1 0.2 3.9 4 0 0 4 4 4 0 AAA-like domain MobB PF03205.9 AEO68877.1 - 0.029 14.0 1.6 14 5.3 0.0 3.9 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4181 PF13789.1 AEO68877.1 - 0.052 13.4 0.2 0.052 13.4 0.2 3.2 4 0 0 4 4 2 0 Domain of unknown function (DUF4181) ATP-synt_ab PF00006.20 AEO68877.1 - 0.058 12.8 1.1 7.2 6.0 0.0 3.0 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.12 AEO68877.1 - 0.064 13.0 5.1 6 6.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 AEO68877.1 - 0.093 12.9 0.1 16 5.7 0.0 3.5 4 0 0 4 4 2 0 RNA helicase MMR_HSR1 PF01926.18 AEO68877.1 - 0.094 12.6 0.0 12 5.8 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 AEO68877.1 - 0.13 12.6 1.9 7.8 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain Ribosomal_L10 PF00466.15 AEO68878.1 - 2.4e-21 75.4 0.0 3.4e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.3 AEO68879.1 - 2.5e-34 117.4 2.8 4.1e-34 116.7 2.0 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 AEO68879.1 - 4.5e-16 58.2 0.1 2.1e-15 56.1 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO68879.1 - 1.8e-10 40.6 0.0 3.5e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO68879.1 - 2.6e-08 33.5 0.0 6.1e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L51_S25_CI-B8 PF05047.11 AEO68880.1 - 4.3e-16 58.3 0.0 6.4e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF187 PF02638.10 AEO68880.1 - 0.014 14.2 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 TIM PF00121.13 AEO68881.1 - 7.7e-92 306.7 0.2 8.7e-92 306.5 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase U3_snoRNA_assoc PF08297.6 AEO68882.1 - 1.1e-11 44.8 1.0 1.1e-11 44.8 0.7 3.4 3 1 0 3 3 3 1 U3 snoRNA associated TPR_11 PF13414.1 AEO68883.1 - 5.9e-06 25.8 0.2 0.00032 20.2 0.0 2.5 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.1 AEO68883.1 - 7.1e-05 22.3 0.0 0.2 11.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 AEO68883.1 - 0.00012 21.7 1.2 0.25 11.3 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 AEO68883.1 - 0.002 18.0 2.5 1.7 8.6 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 AEO68883.1 - 0.017 14.7 0.1 0.47 10.1 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.2 AEO68883.1 - 0.064 13.5 0.1 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF4574 PF15141.1 AEO68883.1 - 0.067 12.9 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4574) Velvet PF11754.3 AEO68884.1 - 1.8e-55 187.7 0.0 3.5e-55 186.7 0.0 1.5 1 0 0 1 1 1 1 Velvet factor Cullin PF00888.17 AEO68886.1 - 2.1e-109 366.7 0.0 3e-109 366.2 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 AEO68886.1 - 1e-18 66.8 0.8 2e-18 65.9 0.5 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain PQ-loop PF04193.9 AEO68887.1 - 3.3e-41 138.6 8.6 3.2e-21 74.6 1.4 2.6 2 0 0 2 2 2 2 PQ loop repeat Cytochrom_C_asm PF01578.15 AEO68887.1 - 1.2 8.5 6.0 7 6.1 0.4 2.5 2 0 0 2 2 2 0 Cytochrome C assembly protein MFS_1 PF07690.11 AEO68888.1 - 7.6e-18 64.3 33.0 7.6e-18 64.3 22.9 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO68888.1 - 2.2e-05 23.0 30.4 0.00028 19.4 6.4 3.5 2 2 1 3 3 3 3 MFS/sugar transport protein ECH PF00378.15 AEO68890.1 - 1.5e-24 86.4 0.1 2.5e-22 79.1 0.1 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Vps51 PF08700.6 AEO68891.1 - 5.5e-09 35.7 0.0 1.6e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 DDE_Tnp_ISL3 PF01610.12 AEO68891.1 - 0.0091 15.6 0.2 0.023 14.2 0.1 1.7 2 0 0 2 2 2 1 Transposase NUDIX-like PF09296.6 AEO68892.1 - 1.3e-18 67.1 0.8 7.5e-18 64.6 0.4 2.3 3 0 0 3 3 3 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.23 AEO68892.1 - 6.9e-18 64.6 0.0 1.5e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 AEO68892.1 - 1.6e-09 37.1 1.3 2.8e-09 36.2 0.9 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Ribosomal_L1 PF00687.16 AEO68893.1 - 1.8e-54 184.4 0.8 2.2e-54 184.1 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ndr PF03096.9 AEO68893.1 - 0.053 11.9 0.0 0.078 11.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family SNF PF00209.13 AEO68893.1 - 0.075 11.4 0.1 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family Zn_clus PF00172.13 AEO68895.1 - 0.00066 19.5 10.8 0.0012 18.6 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.14 AEO68896.1 - 0.32 11.4 2.1 0.94 9.9 0.4 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-C2H2_4 PF13894.1 AEO68897.1 - 0.0018 18.4 12.8 0.0074 16.5 0.3 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO68897.1 - 0.0094 16.2 4.7 0.8 10.1 0.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type SET PF00856.23 AEO68898.1 - 4e-13 49.9 0.0 8.2e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 SET domain Kinetochor_Ybp2 PF08568.5 AEO68899.1 - 1.2e-112 377.2 0.0 1.6e-112 376.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin ATPgrasp_Ter PF15632.1 AEO68900.1 - 0.11 11.2 0.0 0.2 10.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Pkinase PF00069.20 AEO68900.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain COesterase PF00135.23 AEO68901.1 - 7.1e-78 262.6 0.0 1.4e-77 261.6 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO68901.1 - 9.9e-13 48.1 0.3 3.9e-12 46.1 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO68901.1 - 0.00085 19.0 0.6 0.0019 17.9 0.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO68901.1 - 0.0028 16.8 0.3 0.0048 16.1 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family HeLo PF14479.1 AEO68903.1 - 1e-51 175.7 3.7 2e-51 174.7 2.6 1.5 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 AEO68903.1 - 3e-05 23.2 0.2 0.00018 20.6 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 AEO68903.1 - 0.00039 19.6 0.0 0.0011 18.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 AEO68903.1 - 0.027 13.5 0.0 0.061 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Metal_resist PF13801.1 AEO68903.1 - 0.25 11.3 5.9 0.048 13.6 0.6 2.5 3 0 0 3 3 3 0 Heavy-metal resistance ABC_tran PF00005.22 AEO68904.1 - 2.6e-19 69.9 0.0 4.6e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 AEO68904.1 - 2.8e-15 56.0 19.4 5e-15 55.2 13.4 1.4 1 0 0 1 1 1 1 ABC-2 type transporter Zn_clus PF00172.13 AEO68904.1 - 1.1e-06 28.4 1.7 3e-06 27.0 1.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO68904.1 - 3e-06 26.3 0.0 8.2e-06 24.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain AAA_16 PF13191.1 AEO68904.1 - 0.00081 19.4 0.1 0.0032 17.4 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 AEO68904.1 - 0.0031 17.3 0.9 0.0088 15.9 0.1 2.2 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 AEO68904.1 - 0.0049 17.0 0.2 0.018 15.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain DUF258 PF03193.11 AEO68904.1 - 0.0089 15.2 0.1 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 AEO68904.1 - 0.01 15.8 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 AEO68904.1 - 0.015 14.7 0.1 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AEO68904.1 - 0.016 16.0 0.0 0.053 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AEO68904.1 - 0.019 14.4 0.0 0.053 13.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 AEO68904.1 - 0.046 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.7 AEO68904.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 AEO68904.1 - 0.1 12.2 0.1 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 AEO68904.1 - 0.15 11.5 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 AEO68904.1 - 0.25 11.3 0.1 0.54 10.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.16 AEO68904.1 - 0.32 10.2 0.3 0.6 9.3 0.2 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Miro PF08477.8 AEO68904.1 - 0.37 11.2 0.0 0.73 10.3 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Arch_ATPase PF01637.13 AEO68904.1 - 0.49 10.0 0.0 0.87 9.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase SRPRB PF09439.5 AEO68904.1 - 0.54 9.4 0.6 1.1 8.4 0.4 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Rad17 PF03215.10 AEO68904.1 - 1.9 7.0 0.1 2.8 6.5 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 AEO68904.1 - 2.4 8.0 5.2 2 8.3 1.6 2.3 2 0 0 2 2 2 0 AAA domain Corona_nucleoca PF00937.13 AEO68904.1 - 4.8 6.0 6.9 8.9 5.1 4.8 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein NDUFA12 PF05071.11 AEO68905.1 - 2.8e-07 30.9 3.5 5e-07 30.1 0.2 2.6 2 1 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 CH PF00307.26 AEO68906.1 - 2.7e-10 40.2 0.0 4.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain DNA_pol_A PF00476.15 AEO68907.1 - 1.6e-97 326.5 0.0 2.3e-97 326.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A zf-C3HC4_3 PF13920.1 AEO68908.1 - 7.6e-12 44.7 7.6 1e-11 44.2 5.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO68908.1 - 5.2e-11 42.1 9.3 7.5e-11 41.6 6.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO68908.1 - 9.7e-09 35.1 9.6 1.4e-08 34.5 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO68908.1 - 5e-08 32.4 10.0 7.7e-08 31.8 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO68908.1 - 5.5e-08 32.4 8.7 8.3e-08 31.8 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 AEO68908.1 - 9.6e-05 22.1 2.8 0.00016 21.4 2.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 AEO68908.1 - 0.00013 21.8 7.6 0.00023 20.9 5.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 AEO68908.1 - 0.0004 19.8 6.0 0.00068 19.1 4.1 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 AEO68908.1 - 0.002 17.8 2.8 0.002 17.8 2.0 2.4 2 0 0 2 2 2 1 RING-type zinc-finger TerY-C PF15616.1 AEO68908.1 - 0.0059 16.5 0.6 0.0072 16.2 0.4 1.2 1 0 0 1 1 1 1 TerY-C metal binding domain zf-rbx1 PF12678.2 AEO68908.1 - 0.053 13.6 7.3 0.15 12.2 5.1 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 AEO68908.1 - 0.056 13.0 9.0 0.38 10.3 6.3 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.6 AEO68908.1 - 0.15 11.8 2.1 0.21 11.3 1.5 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) RNHCP PF12647.2 AEO68908.1 - 0.17 11.6 3.6 0.28 11.0 2.5 1.3 1 0 0 1 1 1 0 RNHCP domain zf-RING_6 PF14835.1 AEO68908.1 - 0.25 11.1 3.4 0.43 10.4 2.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-CHY PF05495.7 AEO68908.1 - 0.27 11.4 6.1 0.42 10.8 4.2 1.2 1 0 0 1 1 1 0 CHY zinc finger PolC_DP2 PF03833.8 AEO68908.1 - 0.3 8.7 1.6 0.38 8.3 1.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 FYVE PF01363.16 AEO68908.1 - 0.81 9.6 7.0 2.2 8.2 4.8 1.8 1 1 0 1 1 1 0 FYVE zinc finger DZR PF12773.2 AEO68908.1 - 0.95 9.3 4.3 2.3 8.0 3.0 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-MIZ PF02891.15 AEO68908.1 - 2.1 7.9 8.4 5.4 6.6 5.8 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger DUF3414 PF11894.3 AEO68909.1 - 0 1470.4 0.0 0 1470.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) PI3_PI4_kinase PF00454.22 AEO68910.1 - 3.3e-44 151.1 0.0 6.4e-44 150.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 AEO68910.1 - 2.3e-41 141.0 0.3 8.9e-41 139.2 0.0 2.1 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FAT PF02259.18 AEO68910.1 - 1.7e-28 99.6 8.9 3.7e-28 98.5 6.2 1.6 1 0 0 1 1 1 1 FAT domain FATC PF02260.15 AEO68910.1 - 4.1e-11 42.1 0.1 1e-10 40.8 0.1 1.8 1 0 0 1 1 1 1 FATC domain SNF5 PF04855.7 AEO68911.1 - 2.1e-74 250.0 0.1 3.3e-74 249.4 0.1 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 PAT1 PF09770.4 AEO68911.1 - 0.9 7.6 5.7 1.9 6.6 4.0 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_M24 PF00557.19 AEO68912.1 - 3.2e-11 43.2 0.0 4.3e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 FAM176 PF14851.1 AEO68912.1 - 1.7 8.3 5.0 2.8 7.5 3.4 1.4 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 AEO68912.1 - 9 6.6 10.9 19 5.6 7.5 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PHD PF00628.24 AEO68913.1 - 1.2e-14 53.6 16.3 1.9e-08 33.8 5.4 2.3 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.1 AEO68913.1 - 0.00034 20.7 6.4 0.011 15.9 1.0 2.4 2 0 0 2 2 2 2 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 AEO68913.1 - 0.0019 17.9 1.6 0.0019 17.9 1.1 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.1 AEO68913.1 - 0.0098 15.8 2.7 0.16 12.0 0.1 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain C1_1 PF00130.17 AEO68913.1 - 0.037 13.7 13.2 0.12 12.0 0.3 2.6 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 AEO68913.1 - 0.055 12.7 10.3 0.33 10.2 1.9 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Atx10homo_assoc PF09759.4 AEO68913.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain IFT57 PF10498.4 AEO68913.1 - 0.79 8.4 2.0 1.3 7.6 1.4 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 PUF PF00806.14 AEO68914.1 - 8.7e-27 91.0 0.0 2.3e-05 23.6 0.0 5.8 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 AEO68914.1 - 2e-13 49.7 0.0 4.2e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO68914.1 - 7.4e-07 28.9 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO68914.1 - 1.5e-05 24.8 0.0 3.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) BAF1_ABF1 PF04684.8 AEO68914.1 - 1.1 8.0 8.9 2.2 7.0 6.2 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pkinase PF00069.20 AEO68916.1 - 1e-70 237.8 0.0 1.6e-70 237.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO68916.1 - 2.1e-52 177.7 0.0 3.4e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 AEO68916.1 - 9.4e-22 77.1 1.2 2.9e-21 75.6 0.1 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 AEO68916.1 - 5.8e-07 28.7 0.0 1.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 AEO68916.1 - 2.3e-06 27.7 0.0 4.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 AEO68916.1 - 0.0012 19.0 0.5 0.0055 16.9 0.3 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 AEO68916.1 - 0.0079 15.9 0.1 0.0079 15.9 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AEO68916.1 - 0.017 13.9 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 tRNA-synt_2b PF00587.20 AEO68917.1 - 2.1e-68 229.2 0.1 3.4e-68 228.6 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AEO68917.1 - 4.6e-24 84.1 0.2 1.6e-23 82.4 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain DUF818 PF05677.7 AEO68917.1 - 0.064 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Brix PF04427.13 AEO68918.1 - 1.5e-37 129.0 0.0 2.1e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain Cwf_Cwc_15 PF04889.7 AEO68918.1 - 0.11 12.1 16.8 0.23 11.1 11.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.6 AEO68918.1 - 0.12 10.2 2.9 0.17 9.7 2.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 AEO68918.1 - 1.2 6.9 19.5 1.6 6.5 13.5 1.1 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.8 AEO68918.1 - 1.8 7.1 13.9 0.53 8.9 7.7 1.5 1 1 0 1 1 1 0 Paf1 TPT PF03151.11 AEO68919.1 - 4.7e-11 42.5 5.8 4.7e-11 42.5 4.0 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family Mito_fiss_reg PF05308.6 AEO68919.1 - 0.78 9.0 4.6 1.4 8.2 3.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Epimerase PF01370.16 AEO68920.1 - 4.9e-56 189.8 0.0 6.5e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 AEO68920.1 - 9.4e-23 80.5 0.0 8.8e-22 77.3 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 AEO68920.1 - 2.8e-22 78.9 0.0 3.9e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 AEO68920.1 - 3.6e-22 78.4 0.0 1.9e-21 76.1 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 AEO68920.1 - 8.3e-21 73.9 0.0 1.1e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 AEO68920.1 - 9.8e-09 35.4 0.0 2.5e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 AEO68920.1 - 0.001 19.0 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.1 AEO68921.1 - 1.1e-15 57.7 0.1 2.8e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO68921.1 - 3.5e-07 29.9 0.0 1.2e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO68921.1 - 7.2e-07 29.6 0.0 2.5e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO68921.1 - 6.8e-06 26.6 0.2 0.001 19.6 0.0 3.5 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO68921.1 - 8.5e-05 22.9 0.0 0.00027 21.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 AEO68921.1 - 0.00035 20.6 0.0 0.013 15.4 0.0 2.4 1 1 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 AEO68921.1 - 0.00038 19.6 0.0 0.00092 18.3 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 AEO68921.1 - 0.0021 17.1 0.0 0.0036 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 AEO68921.1 - 0.028 13.5 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 AEO68921.1 - 0.068 13.5 0.0 0.29 11.5 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain Pep3_Vps18 PF05131.9 AEO68922.1 - 3.5e-48 162.7 0.0 1.1e-47 161.1 0.0 1.9 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 AEO68922.1 - 7.9e-10 38.4 3.7 2.2e-06 27.3 0.0 3.4 3 1 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 AEO68922.1 - 0.00019 21.1 1.2 0.00044 20.0 0.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 AEO68922.1 - 0.00073 19.2 0.9 0.0014 18.2 0.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DNA_pol3_theta PF06440.6 AEO68922.1 - 0.013 15.0 0.0 0.036 13.6 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III, theta subunit Vps39_2 PF10367.4 AEO68922.1 - 0.028 14.6 0.0 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 TPR_21 PF09976.4 AEO68922.1 - 0.033 14.1 0.7 0.033 14.1 0.5 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 AEO68922.1 - 0.035 14.4 3.0 1 9.7 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2175 PF09943.4 AEO68922.1 - 0.041 13.9 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) PPR_3 PF13812.1 AEO68922.1 - 0.096 13.0 0.0 6.8 7.2 0.0 3.4 3 0 0 3 3 3 0 Pentatricopeptide repeat domain zf-C3HC4_2 PF13923.1 AEO68922.1 - 0.26 11.3 1.0 0.67 10.0 0.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_7 PF13176.1 AEO68922.1 - 0.59 10.0 6.3 59 3.8 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 AEO68922.1 - 2 8.1 4.3 0.45 10.2 0.5 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ATP-synt_C PF00137.16 AEO68923.1 - 9.4e-28 95.9 26.0 3.2e-17 62.1 6.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ABA_GPCR PF12430.3 AEO68923.1 - 0.26 10.3 2.6 4.7 6.3 0.2 2.2 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor TCR_zetazeta PF11628.3 AEO68923.1 - 0.26 10.7 1.6 6.1 6.3 0.1 2.5 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain Asp PF00026.18 AEO68924.1 - 2.7e-66 223.9 1.1 3.3e-66 223.7 0.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO68924.1 - 1.5e-12 47.7 0.3 1.5e-12 47.7 0.2 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO68924.1 - 1.1e-06 29.0 1.6 0.0058 17.1 0.3 3.6 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 AEO68924.1 - 0.00013 21.5 0.0 0.00043 19.8 0.0 1.9 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal NmrA PF05368.8 AEO68925.1 - 2.7e-15 56.2 0.0 1.1e-14 54.2 0.0 2.1 2 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 AEO68925.1 - 4.7e-14 52.7 0.2 2.3e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 AEO68925.1 - 2.8e-07 29.8 0.0 3.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 AEO68925.1 - 8.9e-05 22.0 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.17 AEO68925.1 - 0.00087 19.8 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold KR PF08659.5 AEO68925.1 - 0.0018 18.0 0.1 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 AEO68925.1 - 0.0024 17.8 0.9 0.0036 17.2 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase DapB_N PF01113.15 AEO68925.1 - 0.0098 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 AEO68925.1 - 0.018 15.4 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CoA_binding_2 PF13380.1 AEO68925.1 - 0.022 14.9 0.1 0.062 13.4 0.0 1.8 2 0 0 2 2 2 0 CoA binding domain TrkA_N PF02254.13 AEO68925.1 - 0.025 14.5 0.1 0.071 13.1 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain 3Beta_HSD PF01073.14 AEO68925.1 - 0.072 11.7 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AEO68925.1 - 0.087 11.6 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Semialdhyde_dh PF01118.19 AEO68925.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain WD40 PF00400.27 AEO68926.1 - 1.5e-27 94.4 7.4 3.1e-09 36.3 0.0 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_3 PF13570.1 AEO68926.1 - 0.0026 17.9 0.1 1 9.7 0.0 3.4 3 0 0 3 3 3 2 PQQ-like domain Apc4_WD40 PF12894.2 AEO68926.1 - 0.023 14.1 0.0 0.84 9.1 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PUF PF00806.14 AEO68927.1 - 6.5e-55 179.6 1.3 1.6e-07 30.3 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat MepB PF08877.5 AEO68928.1 - 0.0055 16.2 0.7 2 7.9 0.2 2.9 2 1 1 3 3 3 2 MepB protein ISK_Channel PF02060.10 AEO68929.1 - 0.019 14.5 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Slow voltage-gated potassium channel NS3_envE PF02723.9 AEO68929.1 - 0.17 11.7 1.0 0.29 11.0 0.7 1.3 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E DUF2909 PF11137.3 AEO68929.1 - 0.18 11.5 3.9 0.33 10.7 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) Phosphodiest PF01663.17 AEO68930.1 - 3.4e-15 56.2 0.3 6e-15 55.4 0.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 AEO68930.1 - 0.00087 18.5 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 AEO68930.1 - 0.0041 16.5 0.8 0.0069 15.7 0.5 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF2721 PF11026.3 AEO68930.1 - 0.033 13.8 0.1 0.033 13.8 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) Meth_synt_2 PF01717.13 AEO68931.1 - 1.8e-140 467.4 0.0 5.8e-135 449.4 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 AEO68931.1 - 1e-124 415.8 0.0 1.7e-113 379.0 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 AEO68931.1 - 0.084 11.7 0.0 7.9 5.2 0.0 2.5 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) EF-hand_4 PF12763.2 AEO68932.1 - 3.4e-27 94.1 0.0 9.6e-15 54.2 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 AEO68932.1 - 2.3e-05 24.4 0.1 0.029 14.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 AEO68932.1 - 0.0003 19.8 0.0 0.54 9.6 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 AEO68932.1 - 0.0005 19.7 0.0 1.1 9.2 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain DUF1720 PF08226.6 AEO68932.1 - 0.0024 17.9 23.4 0.0024 17.9 16.2 7.5 5 2 2 7 7 7 2 Domain of unknown function (DUF1720) EF-hand_8 PF13833.1 AEO68932.1 - 0.11 12.1 0.1 22 4.7 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain pair Fork_head PF00250.13 AEO68933.1 - 6.2e-34 115.9 0.4 1.7e-33 114.4 0.3 1.7 2 0 0 2 2 2 1 Fork head domain DUF1649 PF07855.7 AEO68934.1 - 2.8e-62 209.1 0.0 3.9e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) CDK2AP PF09806.4 AEO68934.1 - 0.053 13.7 0.9 0.077 13.2 0.6 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Peroxin-3 PF04882.7 AEO68935.1 - 2.1e-137 458.3 0.0 2.5e-137 458.1 0.0 1.1 1 0 0 1 1 1 1 Peroxin-3 Sybindin PF04099.7 AEO68936.1 - 1.9e-23 82.7 0.0 2.3e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Ribosomal_60s PF00428.14 AEO68936.1 - 0.85 10.0 5.9 1.3 9.4 4.1 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pkinase PF00069.20 AEO68937.1 - 5.6e-57 192.8 0.0 1.1e-56 191.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO68937.1 - 3e-33 114.9 0.0 9.6e-32 110.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO68937.1 - 7.9e-09 34.8 0.0 3.8e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AEO68937.1 - 0.00013 21.8 1.1 0.00071 19.3 0.0 2.6 2 2 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 AEO68938.1 - 3.6e-64 216.4 0.0 2.5e-63 213.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO68938.1 - 1.7e-26 92.8 0.0 2.3e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO68938.1 - 0.0058 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AEO68938.1 - 0.011 14.7 0.0 0.022 13.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 AEO68938.1 - 0.077 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family RNA_pol_L_2 PF13656.1 AEO68940.1 - 2e-05 23.9 0.0 3.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 AEO68940.1 - 0.0016 17.5 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TRAP_alpha PF03896.11 AEO68940.1 - 0.0032 16.5 3.9 0.0036 16.3 2.7 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit YL1 PF05764.8 AEO68940.1 - 0.041 13.4 5.6 0.044 13.3 3.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Spore_coat_CotO PF14153.1 AEO68940.1 - 0.12 11.7 2.6 0.13 11.6 1.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO PBP1_TM PF14812.1 AEO68940.1 - 0.19 12.0 4.7 0.26 11.6 3.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Di19_C PF14571.1 AEO68940.1 - 0.34 11.2 4.5 0.48 10.7 3.1 1.2 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal Nop14 PF04147.7 AEO68940.1 - 1.7 6.4 9.7 1.9 6.3 6.7 1.0 1 0 0 1 1 1 0 Nop14-like family PTRF_SDPR PF15237.1 AEO68940.1 - 1.9 7.8 6.1 2.3 7.5 4.2 1.1 1 0 0 1 1 1 0 PTRF/SDPR family Myc_N PF01056.13 AEO68940.1 - 2.6 7.1 7.9 3.3 6.8 5.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region RRN3 PF05327.6 AEO68940.1 - 3.7 5.5 5.2 4.2 5.3 3.6 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 AEO68940.1 - 4 5.3 6.8 4.3 5.2 4.7 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 AEO68940.1 - 7 5.8 12.0 8.3 5.5 8.3 1.0 1 0 0 1 1 1 0 SDA1 IFT57 PF10498.4 AEO68940.1 - 7.2 5.2 7.5 8.6 4.9 5.2 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Daxx PF03344.10 AEO68940.1 - 9.2 4.6 15.7 11 4.3 10.9 1.0 1 0 0 1 1 1 0 Daxx Family Complex1_LYR PF05347.10 AEO68941.1 - 5e-07 29.4 0.2 1.2e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AEO68941.1 - 1.7e-05 24.9 0.4 3e-05 24.1 0.3 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 AEO68941.1 - 0.00053 20.4 0.1 0.00063 20.1 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like G10 PF01125.12 AEO68942.1 - 3e-61 205.2 2.6 3.4e-61 205.0 1.8 1.0 1 0 0 1 1 1 1 G10 protein zf-C2H2_4 PF13894.1 AEO68943.1 - 0.017 15.4 6.1 0.5 10.8 0.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO68943.1 - 0.061 13.6 5.8 0.23 11.8 0.6 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Lamp PF01299.12 AEO68943.1 - 0.096 11.8 1.7 0.12 11.5 1.2 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) EST1_DNA_bind PF10373.4 AEO68944.1 - 2.4e-51 174.6 0.0 3.5e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 AEO68944.1 - 6.8e-27 94.0 0.5 1.1e-26 93.3 0.3 1.3 1 0 0 1 1 1 1 Telomerase activating protein Est1 DEC-1_C PF04626.8 AEO68944.1 - 0.054 13.6 6.8 0.14 12.3 0.7 2.5 2 0 0 2 2 2 0 Dec-1 protein, C terminal region Cob_adeno_trans PF01923.13 AEO68944.1 - 0.1 12.4 0.4 0.24 11.1 0.3 1.5 1 0 0 1 1 1 0 Cobalamin adenosyltransferase PfkB PF00294.19 AEO68945.1 - 3.8e-68 229.8 0.0 4.4e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 AEO68945.1 - 0.0061 15.7 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Ribosomal_L2_C PF03947.13 AEO68946.1 - 4.6e-39 133.1 3.2 8e-39 132.4 2.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 AEO68946.1 - 5.1e-15 55.1 0.2 1e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM1 PF15612.1 AEO68947.1 - 2e-05 24.3 0.0 5.3e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Nop14 PF04147.7 AEO68947.1 - 0.062 11.2 13.9 0.091 10.6 9.7 1.3 1 0 0 1 1 1 0 Nop14-like family DUF1770 PF08589.5 AEO68948.1 - 2.3e-28 98.7 0.3 3.4e-28 98.1 0.2 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) eRF1_2 PF03464.10 AEO68949.1 - 1.7e-47 161.1 0.1 3.4e-47 160.0 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 AEO68949.1 - 5.3e-40 136.2 0.6 1.1e-39 135.1 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 AEO68949.1 - 2.2e-28 98.4 0.0 4.7e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 GMP_PDE_delta PF05351.6 AEO68949.1 - 0.076 12.8 0.3 0.22 11.3 0.2 1.7 1 0 0 1 1 1 0 GMP-PDE, delta subunit PDT PF00800.13 AEO68950.1 - 1.8e-57 193.8 0.0 2.5e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 AEO68950.1 - 0.00069 19.0 0.0 0.0045 16.4 0.0 2.4 3 0 0 3 3 3 1 ACT domain LRR_6 PF13516.1 AEO68952.1 - 0.00068 19.4 1.1 11 6.4 0.0 6.1 7 0 0 7 7 7 1 Leucine Rich repeat Pkinase PF00069.20 AEO68953.1 - 1.5e-68 230.7 0.0 3.5e-68 229.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO68953.1 - 2.4e-50 171.0 0.0 4.3e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 AEO68953.1 - 1.1e-29 102.4 0.1 4e-29 100.6 0.0 2.0 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 AEO68953.1 - 2.3e-16 59.3 0.1 6.4e-16 57.9 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 AEO68953.1 - 3.7e-15 55.8 0.0 6.7e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 AEO68953.1 - 2.1e-13 50.5 0.0 4.4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 AEO68953.1 - 2.7e-08 33.1 0.0 4.1e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.11 AEO68953.1 - 0.036 13.8 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Sas10 PF09368.5 AEO68955.1 - 1e-29 102.5 6.9 1e-29 102.5 4.8 3.0 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 AEO68955.1 - 3.7e-14 52.6 0.2 1.2e-12 47.8 0.0 3.2 3 0 0 3 3 3 1 Sas10/Utp3/C1D family adh_short PF00106.20 AEO68956.1 - 3.9e-18 65.9 0.4 3.9e-18 65.9 0.3 2.3 2 0 0 2 2 2 1 short chain dehydrogenase DUF3716 PF12511.3 AEO68956.1 - 4.6e-16 58.1 8.3 7.6e-16 57.4 5.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) KR PF08659.5 AEO68956.1 - 1.4e-06 28.1 0.1 4.3e-06 26.5 0.1 1.9 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO68956.1 - 0.00056 19.7 0.0 0.00097 18.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 AEO68956.1 - 0.00096 18.8 0.1 0.0027 17.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PAT1 PF09770.4 AEO68956.1 - 0.027 12.7 18.5 0.038 12.2 12.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.17 AEO68956.1 - 0.069 12.1 2.5 0.12 11.3 1.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Ndc1_Nup PF09531.5 AEO68956.1 - 1.4 7.2 3.6 2.5 6.4 2.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup G-alpha PF00503.15 AEO68957.1 - 5.8e-134 446.6 0.9 7.3e-134 446.3 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 AEO68957.1 - 3.8e-15 55.5 1.5 3.6e-10 39.3 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 AEO68957.1 - 0.0002 20.8 0.0 0.00089 18.7 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.7 AEO68957.1 - 0.0045 16.1 2.5 0.29 10.2 0.0 2.5 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region Miro PF08477.8 AEO68957.1 - 0.0045 17.4 0.1 3.3 8.2 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 AEO68957.1 - 0.014 14.9 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 AEO68957.1 - 0.039 13.3 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 AEO68957.1 - 0.075 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Fungal_trans_2 PF11951.3 AEO68958.1 - 1.2e-06 27.3 0.8 2.8e-05 22.9 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain adh_short PF00106.20 AEO68959.1 - 2e-15 57.1 0.5 2e-15 57.1 0.4 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO68959.1 - 7.1e-07 29.0 0.4 7.1e-07 29.0 0.3 1.9 2 0 0 2 2 2 1 KR domain DUF1180 PF06679.7 AEO68959.1 - 0.082 12.7 0.3 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Shikimate_DH PF01488.15 AEO68959.1 - 0.097 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1771 PF08590.5 AEO68960.1 - 1.6e-22 79.2 8.2 1.6e-22 79.2 5.7 2.1 3 1 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.16 AEO68960.1 - 8.4e-16 57.9 0.3 8.4e-16 57.9 0.2 2.3 2 0 0 2 2 2 1 Smr domain FimP PF09766.4 AEO68960.1 - 0.0067 15.5 10.1 0.0067 15.5 7.0 1.6 2 0 0 2 2 2 1 Fms-interacting protein MDFI PF15316.1 AEO68960.1 - 0.022 14.7 4.4 0.022 14.7 3.0 1.7 2 0 0 2 2 2 0 MyoD family inhibitor FNIP_N PF14636.1 AEO68960.1 - 0.1 13.0 9.4 0.063 13.7 4.5 1.9 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Pex14_N PF04695.8 AEO68960.1 - 1.6 8.8 14.7 0.91 9.5 8.4 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.5 AEO68960.1 - 5.7 5.0 36.2 8 4.5 25.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal KfrA_N PF11740.3 AEO68960.1 - 6.5 7.2 20.2 0.35 11.3 5.8 3.1 2 1 2 4 4 4 0 Plasmid replication region DNA-binding N-term DUF3984 PF13136.1 AEO68960.1 - 7.1 5.7 15.7 0.99 8.5 7.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) DUF912 PF06024.7 AEO68961.1 - 0.0051 16.8 0.0 0.0091 16.0 0.0 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4448 PF14610.1 AEO68961.1 - 0.034 13.6 0.1 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Herpes_gE PF02480.11 AEO68961.1 - 0.11 10.7 0.4 0.14 10.4 0.3 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Pex14_N PF04695.8 AEO68961.1 - 0.13 12.3 0.4 0.19 11.7 0.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RCR PF12273.3 AEO68961.1 - 0.14 12.7 2.1 0.21 12.1 0.0 2.0 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.1 AEO68961.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF543 PF04418.7 AEO68962.1 - 8.9e-30 102.4 0.0 9.7e-30 102.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF2456 PF10445.4 AEO68962.1 - 0.066 13.1 0.0 0.081 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) Urb2 PF10441.4 AEO68963.1 - 3.7e-52 177.1 0.0 9.2e-52 175.8 0.0 1.7 1 0 0 1 1 1 1 Urb2/Npa2 family D123 PF07065.9 AEO68964.1 - 1.9e-71 240.6 0.0 1.5e-59 201.5 0.0 3.1 2 1 0 2 2 2 2 D123 Sigma70_ner PF04546.8 AEO68964.1 - 0.79 9.2 20.8 5.6 6.5 2.2 4.1 4 0 0 4 4 4 0 Sigma-70, non-essential region cwf21 PF08312.7 AEO68965.1 - 2.5e-18 65.6 10.6 2.5e-18 65.6 7.3 1.9 2 0 0 2 2 2 1 cwf21 domain RasGEF PF00617.14 AEO68966.1 - 5.9e-63 212.0 0.4 9.6e-63 211.3 0.3 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 AEO68966.1 - 2.1e-26 92.0 0.4 4.5e-26 90.9 0.3 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 AEO68966.1 - 4.2e-16 58.0 0.1 9.9e-16 56.8 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AEO68966.1 - 4.8e-14 51.6 0.2 1e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AEO68966.1 - 1.4e-13 50.0 0.1 3.6e-13 48.7 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 AEO68966.1 - 2.4e-05 24.1 0.0 5.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 WW domain Ser_hydrolase PF06821.8 AEO68966.1 - 0.13 11.8 0.3 0.24 10.9 0.2 1.3 1 0 0 1 1 1 0 Serine hydrolase Fungal_trans PF04082.13 AEO68967.1 - 4.3e-15 55.2 2.1 4.3e-15 55.2 1.5 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 AEO68967.1 - 2.1e-08 34.0 12.2 1.7e-05 24.8 4.1 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 AEO68967.1 - 0.00025 21.2 14.7 0.035 14.4 4.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO68967.1 - 0.00038 20.5 16.0 0.0041 17.3 3.6 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 AEO68967.1 - 1.2 9.4 4.0 4.9 7.4 1.7 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Glyco_hydro_16 PF00722.16 AEO68968.1 - 3.3e-06 26.5 0.0 4.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HEAT_2 PF13646.1 AEO68969.1 - 4.7e-05 23.5 5.4 0.0017 18.6 0.1 5.3 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.17 AEO68969.1 - 7.1e-05 22.5 6.0 2 8.7 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat NatB_MDM20 PF09797.4 AEO68969.1 - 0.0078 14.9 1.8 0.015 14.0 0.8 1.8 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit HEAT_EZ PF13513.1 AEO68969.1 - 0.096 13.2 8.9 0.38 11.2 0.0 5.7 7 0 0 7 7 7 0 HEAT-like repeat mRNA_cap_enzyme PF01331.14 AEO68971.1 - 1.2e-50 171.9 0.2 1.7e-50 171.3 0.2 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 AEO68971.1 - 8.5e-22 77.4 0.0 2.4e-21 76.0 0.0 1.8 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 AEO68971.1 - 8.9e-09 35.0 2.1 2e-07 30.5 0.0 2.8 2 1 0 2 2 2 1 ATP dependent DNA ligase domain TSA PF03249.8 AEO68971.1 - 0.0085 14.6 8.1 0.012 14.1 5.6 1.1 1 0 0 1 1 1 1 Type specific antigen PX PF00787.19 AEO68972.1 - 1.3e-18 66.8 0.0 4.9e-18 64.9 0.0 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 AEO68972.1 - 2e-14 53.4 12.6 4.5e-08 32.6 0.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3_WASP_bdg PF10456.4 AEO68972.1 - 0.0011 18.3 0.1 0.011 15.0 0.4 2.1 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein RNA_polI_A14 PF08203.6 AEO68972.1 - 0.39 10.9 4.7 0.61 10.3 0.4 2.8 2 1 1 3 3 3 0 Yeast RNA polymerase I subunit RPA14 TPR_1 PF00515.23 AEO68973.1 - 1.2e-35 119.6 20.0 5e-05 22.7 0.0 12.4 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_11 PF13414.1 AEO68973.1 - 7.8e-33 111.9 33.5 6.7e-09 35.2 0.2 11.8 9 3 5 14 14 14 8 TPR repeat TPR_2 PF07719.12 AEO68973.1 - 3.4e-32 107.7 26.5 0.0013 18.4 0.0 13.3 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_8 PF13181.1 AEO68973.1 - 1e-30 103.1 22.0 1.1e-05 24.8 0.1 12.3 12 1 0 12 12 11 6 Tetratricopeptide repeat TPR_12 PF13424.1 AEO68973.1 - 9.1e-24 83.1 37.1 7.4e-08 32.2 0.1 11.0 8 3 3 11 11 11 7 Tetratricopeptide repeat TPR_7 PF13176.1 AEO68973.1 - 6.5e-21 72.4 22.3 0.0003 20.3 0.0 11.8 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 AEO68973.1 - 1.1e-19 70.5 32.7 5.5e-07 29.8 0.5 10.3 9 3 2 11 11 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 AEO68973.1 - 1.4e-16 60.7 46.0 0.00018 22.0 0.1 11.6 9 3 2 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 AEO68973.1 - 2.7e-16 58.6 42.6 0.00019 21.7 0.0 14.4 13 6 5 18 18 16 5 Tetratricopeptide repeat TPR_17 PF13431.1 AEO68973.1 - 3.2e-14 51.8 11.0 0.09 13.0 0.1 10.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_6 PF13174.1 AEO68973.1 - 5.1e-13 48.5 20.5 0.0008 19.7 0.0 11.2 12 0 0 12 12 10 3 Tetratricopeptide repeat Apc3 PF12895.2 AEO68973.1 - 4e-07 30.0 20.4 0.0027 17.8 0.7 7.4 7 1 0 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 AEO68973.1 - 0.00022 21.0 19.9 0.12 12.4 0.0 8.9 10 0 0 10 10 9 2 Tetratricopeptide repeat PPR PF01535.15 AEO68973.1 - 0.03 14.2 0.2 46 4.3 0.0 5.0 5 0 0 5 5 5 0 PPR repeat PrpF PF04303.8 AEO68975.1 - 2.1e-60 204.4 2.4 3.3e-58 197.2 0.9 2.1 1 1 1 2 2 2 2 PrpF protein Serglycin PF04360.7 AEO68975.1 - 0.15 11.7 0.3 0.28 10.8 0.2 1.3 1 0 0 1 1 1 0 Serglycin DUF3246 PF11596.3 AEO68975.1 - 0.23 10.7 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Glyco_hydro_47 PF01532.15 AEO68975.1 - 0.32 9.6 0.0 0.48 9.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 AAA_2 PF07724.9 AEO68976.1 - 8.5e-48 162.4 0.0 2.7e-46 157.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 AEO68976.1 - 1.9e-27 96.0 0.0 7.6e-15 55.2 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 AEO68976.1 - 1.8e-21 75.8 1.3 1.8e-21 75.8 0.9 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 AEO68976.1 - 1.6e-16 60.8 13.6 3.7e-06 27.0 0.0 6.8 3 3 2 6 6 5 2 AAA ATPase domain AAA_5 PF07728.9 AEO68976.1 - 4.6e-16 58.7 0.0 5.1e-10 39.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AEO68976.1 - 1.1e-13 51.4 0.3 4.5e-05 23.5 0.0 4.1 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 AEO68976.1 - 1.4e-09 37.6 0.0 6.4e-06 25.7 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 AEO68976.1 - 4.2e-08 34.0 4.8 0.01 16.6 0.0 3.7 2 2 0 2 2 2 2 AAA domain Clp_N PF02861.15 AEO68976.1 - 4.4e-08 32.9 2.1 0.00057 19.7 0.0 4.0 3 0 0 3 3 3 2 Clp amino terminal domain IstB_IS21 PF01695.12 AEO68976.1 - 1.6e-07 30.9 0.0 0.015 14.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 AEO68976.1 - 2.5e-07 31.0 0.1 0.015 15.5 0.0 3.4 3 0 0 3 3 2 2 AAA domain Arch_ATPase PF01637.13 AEO68976.1 - 6.5e-07 29.2 5.4 0.0082 15.8 0.1 4.9 5 1 0 5 5 4 1 Archaeal ATPase AAA_19 PF13245.1 AEO68976.1 - 1.7e-06 27.6 3.4 0.031 14.0 0.1 3.5 3 0 0 3 3 2 2 Part of AAA domain Mg_chelatase PF01078.16 AEO68976.1 - 4.1e-06 26.1 0.1 0.091 11.9 0.1 3.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 AEO68976.1 - 2.1e-05 24.5 0.0 0.27 11.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 AEO68976.1 - 4e-05 22.6 0.1 0.0053 15.6 0.0 2.7 2 1 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.17 AEO68976.1 - 5.4e-05 23.3 0.0 0.4 10.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 AEO68976.1 - 7.7e-05 22.6 0.0 0.21 11.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 AEO68976.1 - 8.6e-05 22.1 0.0 0.65 9.6 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 AEO68976.1 - 0.0002 21.6 0.4 0.45 10.8 0.0 3.3 3 0 0 3 3 2 1 ABC transporter MobB PF03205.9 AEO68976.1 - 0.00025 20.7 0.0 0.61 9.7 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 AEO68976.1 - 0.0003 20.2 1.9 1.8 7.9 0.0 3.9 3 1 0 4 4 4 2 AAA domain ResIII PF04851.10 AEO68976.1 - 0.00031 20.6 0.0 0.18 11.5 0.0 3.5 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_29 PF13555.1 AEO68976.1 - 0.00046 19.6 0.0 0.39 10.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 AEO68976.1 - 0.00049 19.3 0.0 0.25 10.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 AEO68976.1 - 0.00072 19.0 6.8 0.14 11.5 0.1 5.1 5 1 0 5 5 5 1 AAA-like domain Torsin PF06309.6 AEO68976.1 - 0.0014 18.4 0.0 0.0055 16.5 0.0 1.9 2 0 0 2 2 1 1 Torsin NTPase_1 PF03266.10 AEO68976.1 - 0.0016 18.1 0.0 0.18 11.4 0.0 3.4 3 0 0 3 3 3 1 NTPase AAA_24 PF13479.1 AEO68976.1 - 0.0017 17.9 0.0 1.7 8.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 AEO68976.1 - 0.0023 17.6 0.0 0.28 10.8 0.0 2.8 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 AEO68976.1 - 0.017 14.7 0.0 6.4 6.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 AEO68976.1 - 0.017 14.5 0.0 4.8 6.5 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_21 PF13304.1 AEO68976.1 - 0.018 15.0 0.3 2.4 8.0 0.0 2.9 4 0 0 4 4 2 0 AAA domain MMR_HSR1 PF01926.18 AEO68976.1 - 0.057 13.3 0.2 2.6 8.0 0.0 3.5 3 1 0 3 3 3 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 AEO68976.1 - 0.066 12.6 0.0 6.2 6.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 AEO68976.1 - 0.069 11.9 0.0 0.69 8.7 0.0 2.4 3 0 0 3 3 3 0 NB-ARC domain ATP_bind_1 PF03029.12 AEO68976.1 - 0.076 12.5 0.0 9.8 5.6 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 AEO68976.1 - 0.12 12.9 0.0 2.6 8.5 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein Peptidase_M16 PF00675.15 AEO68976.1 - 0.19 11.4 1.3 6.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) IncA PF04156.9 AEO68976.1 - 0.51 9.9 6.4 1.5 8.3 4.4 1.9 1 0 0 1 1 1 0 IncA protein Snapin_Pallidin PF14712.1 AEO68976.1 - 0.52 10.6 7.6 4.2 7.7 1.8 2.9 2 0 0 2 2 2 0 Snapin/Pallidin V_ATPase_I PF01496.14 AEO68976.1 - 1.2 6.9 3.5 2 6.1 2.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 AEO68976.1 - 1.9 8.7 14.8 2.3 8.5 0.0 3.8 3 1 0 3 3 2 0 AAA domain Macoilin PF09726.4 AEO68976.1 - 2.1 6.5 9.4 3.5 5.8 6.5 1.2 1 0 0 1 1 1 0 Transmembrane protein Mhr1 PF12829.2 AEO68977.1 - 1.7e-26 91.8 0.0 2.6e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination LEA_3 PF03242.8 AEO68977.1 - 3 8.1 7.4 1.1 9.5 1.0 2.4 2 0 0 2 2 2 0 Late embryogenesis abundant protein Sulfotransfer_3 PF13469.1 AEO68978.1 - 0.00037 21.4 0.0 0.0012 19.7 0.0 1.9 1 1 1 2 2 2 1 Sulfotransferase family SR-25 PF10500.4 AEO68978.1 - 4.2 6.7 7.8 0.78 9.1 2.8 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PIG-X PF08320.7 AEO68979.1 - 1.4e-64 217.2 0.0 1.8e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 PIG-X / PBN1 Homeobox PF00046.24 AEO68980.1 - 3.4e-10 39.3 0.0 1e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 Homeobox domain Rhodanese PF00581.15 AEO68980.1 - 7.7e-09 35.9 0.0 1.8e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain DUF4372 PF14294.1 AEO68980.1 - 0.0083 15.9 0.4 0.02 14.7 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4372) Cyclase PF04199.8 AEO68980.1 - 0.049 13.3 0.6 7.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Putative cyclase Homeobox_KN PF05920.6 AEO68981.1 - 0.00044 19.8 0.6 0.00084 18.9 0.4 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 AEO68981.1 - 0.0012 18.3 1.2 0.0027 17.2 0.8 1.7 1 0 0 1 1 1 1 Homeobox domain BTV_NS2 PF04514.7 AEO68981.1 - 5.6 5.7 12.0 7 5.4 8.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Tropomyosin_1 PF12718.2 AEO68982.1 - 0.00042 20.1 6.9 0.019 14.8 0.8 2.5 1 1 1 2 2 2 2 Tropomyosin like TMF_TATA_bd PF12325.3 AEO68982.1 - 0.0013 18.4 8.2 0.055 13.1 0.1 2.7 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding HALZ PF02183.13 AEO68982.1 - 0.0019 17.8 6.8 0.83 9.4 0.3 4.2 3 1 1 4 4 4 1 Homeobox associated leucine zipper ERM PF00769.14 AEO68982.1 - 0.0037 16.8 0.9 0.0037 16.8 0.6 2.3 2 1 0 3 3 3 1 Ezrin/radixin/moesin family Rootletin PF15035.1 AEO68982.1 - 0.0083 16.1 0.3 0.0083 16.1 0.2 2.4 1 1 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.4 AEO68982.1 - 0.023 14.5 8.6 1.3 8.8 1.2 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 AEO68982.1 - 0.072 11.7 7.4 0.12 11.0 5.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 AEO68982.1 - 0.075 12.0 5.2 0.14 11.1 3.6 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Sipho_Gp157 PF05565.6 AEO68982.1 - 0.13 11.7 1.7 2.3 7.7 0.3 2.3 1 1 1 2 2 2 0 Siphovirus Gp157 DUF972 PF06156.8 AEO68982.1 - 0.45 10.8 7.4 1.7 9.0 0.1 3.2 2 1 2 4 4 3 0 Protein of unknown function (DUF972) GAS PF13851.1 AEO68982.1 - 0.65 9.1 6.6 1.8 7.7 4.0 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CCDC155 PF14662.1 AEO68982.1 - 0.81 9.2 13.2 0.36 10.4 6.0 2.3 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 Striatin PF08232.7 AEO68982.1 - 1.1 9.5 5.3 0.89 9.8 0.2 2.6 2 0 0 2 2 2 0 Striatin family BLOC1_2 PF10046.4 AEO68982.1 - 1.5 8.9 8.0 6.9 6.8 0.8 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF904 PF06005.7 AEO68982.1 - 2.7 8.3 12.3 3.7 7.9 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF904) 2OG-FeII_Oxy_3 PF13640.1 AEO68983.1 - 0.013 15.9 0.1 3.3 8.2 0.0 2.5 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 AEO68983.1 - 0.026 14.8 0.0 0.68 10.2 0.0 2.3 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.13 AEO68984.1 - 1.8e-10 40.5 11.0 2.6e-10 40.0 7.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO68984.1 - 4.3e-08 32.3 0.0 1e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_6 PF00970.19 AEO68985.1 - 2.5e-27 94.8 0.0 3.8e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 AEO68985.1 - 8.3e-22 77.8 0.0 2e-21 76.5 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 AEO68985.1 - 3.2e-05 23.8 0.0 0.0016 18.3 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 AEO68985.1 - 0.033 14.1 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF3605 PF12239.3 AEO68986.1 - 4.6e-56 189.0 0.0 5.6e-56 188.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) DUF788 PF05620.6 AEO68987.1 - 4.4e-45 153.5 0.0 4.9e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) DUF2955 PF11168.3 AEO68987.1 - 0.002 17.8 0.7 0.53 9.9 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2955) FA_desaturase PF00487.19 AEO68987.1 - 1.3 8.4 9.6 4.2 6.7 6.7 1.6 1 1 1 2 2 2 0 Fatty acid desaturase TPR_11 PF13414.1 AEO68988.1 - 1.7e-38 130.0 24.8 1.2e-13 50.4 3.5 7.3 5 2 2 7 7 7 6 TPR repeat TPR_1 PF00515.23 AEO68988.1 - 4.2e-36 121.0 22.1 1.2e-07 30.9 0.1 9.4 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 AEO68988.1 - 7e-35 116.1 27.6 2.7e-06 26.8 0.1 10.3 10 0 0 10 10 10 7 Tetratricopeptide repeat Apc3 PF12895.2 AEO68988.1 - 7.9e-32 109.2 19.3 1.3e-21 76.4 0.1 4.7 5 0 0 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 AEO68988.1 - 4.7e-26 88.5 6.4 3.6e-05 23.2 0.1 9.4 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 AEO68988.1 - 2.3e-25 88.3 21.7 5.4e-09 35.8 0.1 6.7 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 AEO68988.1 - 1.6e-22 79.6 26.0 2.4e-07 31.2 0.4 7.9 5 3 2 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 AEO68988.1 - 1.3e-21 75.0 15.2 0.017 15.7 0.1 9.7 5 1 5 10 10 9 6 Tetratricopeptide repeat TPR_17 PF13431.1 AEO68988.1 - 2.4e-20 70.9 11.8 0.0062 16.6 0.2 8.4 10 0 0 10 10 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 AEO68988.1 - 8.9e-20 70.8 13.1 2.1e-07 31.1 1.7 6.5 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 AEO68988.1 - 5.2e-19 66.4 9.5 0.0018 17.9 0.0 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 AEO68988.1 - 1.5e-12 47.0 10.1 0.12 12.9 0.0 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 AEO68988.1 - 3.3e-05 23.6 8.7 0.046 13.5 0.2 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF2225 PF09986.4 AEO68988.1 - 0.00016 21.2 0.9 0.08 12.3 0.3 3.1 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_15 PF13429.1 AEO68988.1 - 0.00062 18.9 11.1 0.017 14.2 0.4 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AEO68988.1 - 0.0038 17.0 10.4 2.8 7.8 0.3 5.2 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 AEO68988.1 - 0.0081 16.4 1.0 1.2e+02 3.6 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat Metaviral_G PF09595.5 AEO68988.1 - 0.06 12.9 1.9 0.12 12.0 1.3 1.4 1 0 0 1 1 1 0 Metaviral_G glycoprotein APP_E2 PF12925.2 AEO68988.1 - 0.32 10.5 3.8 6.7 6.2 0.0 3.0 1 1 0 2 2 2 0 E2 domain of amyloid precursor protein MIT PF04212.13 AEO68988.1 - 0.37 10.7 8.3 2.3 8.1 0.0 4.2 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 AEO68988.1 - 2.1 8.4 15.7 17 5.5 0.0 6.3 6 1 1 7 7 5 0 Tetratricopeptide repeat Histone PF00125.19 AEO68989.1 - 1.6e-15 56.9 0.1 1.9e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 AEO68989.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 AEO68989.1 - 0.00011 22.3 0.1 0.00015 21.8 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AEO68989.1 - 0.00029 20.8 0.1 0.00053 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 AEO68989.1 - 0.012 15.3 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 AEO68989.1 - 0.02 14.1 0.0 0.02 14.1 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 AEO68989.1 - 0.15 11.8 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Sedlin_N PF04628.8 AEO68990.1 - 2.9e-43 146.8 0.0 3.3e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 AEO68990.1 - 3.8e-06 26.6 0.1 8.5e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family L31 PF09784.4 AEO68991.1 - 1.2e-48 163.4 2.5 1.3e-48 163.3 1.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Val_tRNA-synt_C PF10458.4 AEO68991.1 - 0.27 11.3 2.2 1.9 8.6 0.5 2.5 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm RRM_1 PF00076.17 AEO68992.1 - 5.3e-17 61.2 0.4 8.7e-17 60.5 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO68992.1 - 2.1e-13 50.0 0.0 4e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO68992.1 - 4.9e-09 35.9 0.1 8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup88 PF10168.4 AEO68993.1 - 3.5e-06 25.1 1.4 0.01 13.6 0.0 3.1 3 0 0 3 3 3 3 Nuclear pore component Nup160 PF11715.3 AEO68993.1 - 0.0099 14.0 0.1 0.015 13.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 FliT PF05400.8 AEO68993.1 - 0.023 15.0 1.3 0.023 15.0 0.9 3.1 3 0 0 3 3 3 0 Flagellar protein FliT Snapin_Pallidin PF14712.1 AEO68993.1 - 0.038 14.3 4.2 0.2 11.9 0.5 3.0 3 0 0 3 3 3 0 Snapin/Pallidin Alpha-2-MRAP_C PF06401.6 AEO68993.1 - 0.057 13.2 1.0 0.1 12.4 0.7 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain AATF-Che1 PF13339.1 AEO68993.1 - 2.3 8.3 7.5 98 3.1 5.2 2.4 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF972 PF06156.8 AEO68993.1 - 9 6.7 5.9 37 4.7 3.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Serglycin PF04360.7 AEO68994.1 - 1.8 8.2 8.0 1 9.0 0.1 2.9 3 0 0 3 3 3 0 Serglycin PAT1 PF09770.4 AEO68994.1 - 2.4 6.3 8.7 3.1 5.9 6.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 AEO68994.1 - 3.4 7.7 15.2 2.3 8.2 1.6 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SOG2 PF10428.4 AEO68994.1 - 3.9 6.0 10.3 5.5 5.5 7.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.4 AEO68994.1 - 8.7 4.4 8.3 11 4.1 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein PI3_PI4_kinase PF00454.22 AEO68995.1 - 7.2e-31 107.4 0.0 1.2e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 AEO68995.1 - 2.1e-18 65.8 0.0 4.5e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 Cep57_MT_bd PF06657.8 AEO68995.1 - 0.11 12.5 0.1 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 PI3Ka PF00613.15 AEO68995.1 - 0.19 10.8 0.3 0.35 10.0 0.2 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CBFD_NFYB_HMF PF00808.18 AEO68997.1 - 3.5e-12 46.1 0.8 5.6e-12 45.5 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AEO68997.1 - 0.00011 22.2 0.6 0.00019 21.4 0.4 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 F-box-like PF12937.2 AEO68998.1 - 3.5e-07 29.8 0.1 7.7e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO68998.1 - 0.0003 20.3 1.2 0.0004 19.9 0.1 1.8 2 0 0 2 2 2 1 F-box domain FGGY_C PF02782.11 AEO68999.1 - 3.2e-27 95.4 0.0 6.6e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 AEO68999.1 - 3.1e-22 79.0 0.0 4e-13 49.2 0.0 2.5 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Sad1_UNC PF07738.8 AEO69000.1 - 3.8e-36 123.8 0.0 6.1e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Muskelin_N PF06588.6 AEO69000.1 - 0.013 15.1 0.1 0.028 14.1 0.1 1.4 1 0 0 1 1 1 0 Muskelin N-terminus RRM_2 PF04059.7 AEO69001.1 - 4.2e-39 132.4 0.4 6.9e-39 131.7 0.3 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 AEO69001.1 - 0.089 12.4 0.1 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec15 PF04091.7 AEO69002.1 - 2.1e-112 375.4 0.5 2.1e-112 375.4 0.4 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.1 AEO69002.1 - 0.0016 17.8 3.7 0.0049 16.3 2.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) CBFD_NFYB_HMF PF00808.18 AEO69003.1 - 1.4e-19 69.8 0.6 2.5e-19 69.0 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AEO69003.1 - 2.1e-11 43.7 0.1 3.7e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 AEO69003.1 - 0.025 14.3 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X tRNA-synt_1b PF00579.20 AEO69004.1 - 4.6e-57 193.3 0.0 3.6e-28 98.5 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetases class I (W and Y) Fcf2 PF08698.6 AEO69004.1 - 2.7e-26 91.4 0.2 5.5e-26 90.4 0.2 1.5 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Ribosomal_S10 PF00338.17 AEO69004.1 - 9.9e-21 73.4 0.0 2e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Peptidase_M24 PF00557.19 AEO69006.1 - 5.5e-45 153.5 0.0 8e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 AEO69006.1 - 2.6e-25 89.4 0.3 6.9e-20 71.8 0.0 2.6 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain FUN14 PF04930.10 AEO69007.1 - 0.00013 22.2 3.8 0.0003 20.9 2.1 2.0 2 1 0 2 2 2 1 FUN14 family ATP-synt_B PF00430.13 AEO69008.1 - 2.3 8.0 12.9 0.38 10.5 5.6 2.1 3 0 0 3 3 3 0 ATP synthase B/B' CF(0) TIP41 PF04176.8 AEO69009.1 - 9.6e-64 213.9 0.0 1.3e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.20 AEO69010.1 - 2e-70 236.8 0.0 2.6e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO69010.1 - 1.8e-44 151.7 0.0 2.3e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO69010.1 - 3.3e-07 29.5 0.0 1.2e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AEO69010.1 - 0.00029 19.9 0.1 0.00048 19.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO69010.1 - 0.023 14.4 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 AEO69010.1 - 0.042 13.1 0.1 0.083 12.2 0.0 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_M76 PF09768.4 AEO69011.1 - 5.4e-33 113.8 0.0 6.9e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 AEO69011.1 - 0.0016 18.0 0.2 0.0016 18.0 0.1 1.7 2 1 0 2 2 2 1 SprT-like family Peptidase_MA_2 PF13485.1 AEO69011.1 - 0.018 15.0 0.3 0.04 13.9 0.1 1.6 2 0 0 2 2 2 0 Peptidase MA superfamily DUF2268 PF10026.4 AEO69011.1 - 0.053 12.8 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) AA_kinase PF00696.23 AEO69012.1 - 7e-40 137.0 1.8 1.1e-39 136.4 1.2 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 AEO69012.1 - 5.5e-11 42.0 12.6 8.6e-11 41.4 6.6 2.7 2 1 0 2 2 2 1 PUA domain UPF0113 PF03657.8 AEO69013.1 - 4.5e-07 29.6 0.0 6.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) EGF_MSP1_1 PF12946.2 AEO69013.1 - 0.033 13.9 0.5 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 MSP1 EGF domain 1 PUA PF01472.15 AEO69013.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 PUA domain GMC_oxred_C PF05199.8 AEO69014.1 - 4.2e-24 85.4 0.1 7.6e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 AEO69014.1 - 1.4e-21 76.9 0.0 2.9e-21 75.8 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.13 AEO69014.1 - 3.2e-11 42.6 11.8 1.1e-10 40.9 8.2 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.19 AEO69014.1 - 1.2e-08 34.2 0.8 0.00052 18.9 0.3 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 AEO69014.1 - 9.4e-07 28.0 0.8 0.00019 20.4 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AEO69014.1 - 8.4e-06 25.9 0.6 0.013 15.5 0.5 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO69014.1 - 0.00032 19.9 0.1 0.45 9.5 0.2 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase DOMON PF03351.12 AEO69014.1 - 0.00061 19.7 0.1 0.0019 18.1 0.1 1.8 1 0 0 1 1 1 1 DOMON domain NAD_binding_8 PF13450.1 AEO69014.1 - 0.0013 18.7 0.4 0.0038 17.2 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 AEO69014.1 - 0.0036 15.8 0.2 0.0058 15.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 AEO69014.1 - 0.016 15.0 0.1 0.034 14.0 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO69014.1 - 0.018 15.4 0.3 2.1 8.8 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO69014.1 - 0.018 14.1 0.2 0.033 13.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 AEO69014.1 - 0.07 12.1 0.2 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 AEO69014.1 - 0.2 10.5 0.2 0.35 9.7 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Acetyltransf_1 PF00583.19 AEO69015.1 - 0.00065 19.6 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Arf PF00025.16 AEO69016.1 - 1.1e-67 226.6 0.4 1.2e-67 226.4 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 AEO69016.1 - 3.8e-12 45.6 1.3 3.8e-07 29.1 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 AEO69016.1 - 5.1e-12 45.4 0.0 6e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO69016.1 - 5.4e-11 43.0 0.0 7.3e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 AEO69016.1 - 3.9e-10 39.2 0.0 4.7e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AEO69016.1 - 7e-09 35.6 0.0 8.8e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 AEO69016.1 - 2e-07 30.3 0.0 2.3e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 AEO69016.1 - 1.2e-05 24.8 0.0 0.00068 19.1 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 AEO69016.1 - 0.0033 18.2 0.2 0.0053 17.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 AEO69016.1 - 0.019 14.2 0.3 0.048 12.9 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.7 AEO69016.1 - 0.024 14.2 0.2 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.18 AEO69016.1 - 0.041 13.7 0.0 0.43 10.3 0.0 2.0 1 1 1 2 2 2 0 Dynamin family PduV-EutP PF10662.4 AEO69016.1 - 0.052 13.0 0.0 0.099 12.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.13 AEO69016.1 - 0.073 12.1 0.1 0.16 11.0 0.0 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase DUF4045 PF13254.1 AEO69017.1 - 6.2e-74 249.7 35.4 1.2e-44 153.2 16.2 5.4 3 3 2 5 5 5 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 AEO69017.1 - 5.6e-09 35.5 0.0 0.0056 16.3 0.0 3.0 2 0 0 2 2 2 2 Gelsolin repeat AmoC PF04896.7 AEO69017.1 - 1.5 7.8 0.0 2.4 7.1 0.0 1.2 1 0 0 1 1 1 0 Ammonia monooxygenase/methane monooxygenase, subunit C Med10 PF09748.4 AEO69018.1 - 1.3e-40 138.1 0.1 1.6e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Methyltransf_23 PF13489.1 AEO69019.1 - 1.2e-25 90.1 0.0 1.8e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO69019.1 - 8.3e-10 39.2 0.0 4.4e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO69019.1 - 1.4e-08 34.4 0.0 9.4e-08 31.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO69019.1 - 9.2e-08 32.4 0.0 1.6e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO69019.1 - 3.5e-06 27.4 0.0 6.9e-05 23.2 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO69019.1 - 0.0001 22.6 0.0 0.00023 21.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AEO69019.1 - 0.0012 18.0 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 AEO69019.1 - 0.0081 15.2 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 AEO69019.1 - 0.021 14.8 0.0 0.06 13.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 AEO69019.1 - 0.021 14.7 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 AEO69019.1 - 0.023 14.0 0.0 0.059 12.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 AEO69019.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase bZIP_1 PF00170.16 AEO69020.1 - 5.1e-05 23.1 8.4 5.1e-05 23.1 5.8 2.0 2 0 0 2 2 2 1 bZIP transcription factor Nop53 PF07767.6 AEO69020.1 - 0.18 10.7 8.1 0.25 10.2 5.6 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) GvpL_GvpF PF06386.6 AEO69020.1 - 0.19 11.2 2.5 0.3 10.6 1.7 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4407 PF14362.1 AEO69020.1 - 1.1 8.1 5.2 0.71 8.7 2.5 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.10 AEO69020.1 - 3.1 7.6 11.9 1.5 8.6 5.9 2.1 2 0 0 2 2 2 0 Basic region leucine zipper Stm1_N PF09598.5 AEO69021.1 - 1.2e-10 41.8 0.2 1.2e-10 41.8 0.2 4.6 3 2 1 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.10 AEO69021.1 - 6.4e-07 29.8 12.0 6.4e-07 29.8 8.3 2.3 3 0 0 3 3 3 1 Hyaluronan / mRNA binding family BTV_NS2 PF04514.7 AEO69021.1 - 0.18 10.6 2.9 0.23 10.3 2.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 MFS_1 PF07690.11 AEO69022.1 - 4.9e-14 51.8 41.9 4.9e-08 32.0 6.9 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 AEO69022.1 - 0.0017 16.8 9.4 0.0027 16.1 2.6 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Mtc PF03820.12 AEO69023.1 - 3.8e-105 350.9 0.0 7.8e-76 254.6 0.0 2.0 1 1 1 2 2 2 2 Tricarboxylate carrier Pkinase PF00069.20 AEO69024.1 - 3e-59 200.3 0.0 4.4e-59 199.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO69024.1 - 1.2e-19 70.4 0.0 5.8e-19 68.1 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 AEO69024.1 - 0.042 13.1 0.3 0.51 9.6 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Lactamase_B_2 PF12706.2 AEO69026.1 - 2.5e-33 115.2 0.0 7.9e-33 113.6 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 AEO69026.1 - 9.9e-26 89.0 0.0 2.1e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 AEO69026.1 - 3.4e-08 33.3 0.1 8.8e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF2183 PF09949.4 AEO69027.1 - 1.9e-30 104.7 0.0 3.5e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 AEO69027.1 - 0.016 14.7 0.0 0.058 12.9 0.0 1.8 1 1 1 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) DEAD PF00270.24 AEO69028.1 - 2.9e-44 150.5 0.0 6.2e-44 149.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO69028.1 - 1.3e-24 85.8 0.0 3.3e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 AEO69028.1 - 0.0049 15.3 0.5 0.032 12.6 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) ResIII PF04851.10 AEO69028.1 - 0.044 13.6 3.8 0.12 12.2 0.0 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Glyco_hydro_16 PF00722.16 AEO69030.1 - 2.3e-09 36.7 0.0 3.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Flavin_Reduct PF01613.13 AEO69031.1 - 2.6e-17 63.0 0.1 3.8e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain PDEase_II PF02112.10 AEO69032.1 - 1.6e-56 191.6 0.0 4.4e-50 170.4 0.0 2.4 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 AEO69032.1 - 2.7e-05 23.8 0.0 4.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AEO69032.1 - 0.0019 17.8 0.5 0.0088 15.7 0.3 2.1 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily DUF3693 PF12472.3 AEO69032.1 - 0.029 13.9 0.5 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 Phage related protein DUF1843 PF08898.5 AEO69033.1 - 0.26 11.3 6.2 6.3 6.9 1.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) PGA2 PF07543.7 AEO69033.1 - 3.6 7.3 8.9 9.4 6.0 1.3 2.8 4 0 0 4 4 4 0 Protein trafficking PGA2 zf-MYND PF01753.13 AEO69034.1 - 1.6e-11 43.9 15.6 2.8e-11 43.1 10.8 1.4 1 0 0 1 1 1 1 MYND finger AMP-binding PF00501.23 AEO69035.1 - 1.7e-59 201.3 0.6 5.2e-32 110.7 0.0 4.7 3 2 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.6 AEO69035.1 - 6.9e-12 45.9 0.1 2.5e-11 44.1 0.1 2.0 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 AEO69035.1 - 0.0036 17.0 1.0 0.0084 15.8 0.7 1.6 1 0 0 1 1 1 1 Gas vesicle protein G HET PF06985.6 AEO69036.1 - 1.4e-07 31.7 0.0 2.5e-05 24.4 0.0 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glu_syn_central PF04898.9 AEO69036.1 - 0.47 9.6 0.0 0.79 8.9 0.0 1.2 1 0 0 1 1 1 0 Glutamate synthase central domain PX PF00787.19 AEO69038.1 - 1.5e-13 50.4 0.0 2.6e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 AEO69038.1 - 0.00032 20.3 3.9 0.00063 19.3 2.7 1.5 1 0 0 1 1 1 1 SNARE domain NPV_P10 PF05531.7 AEO69038.1 - 0.21 11.8 1.1 0.37 11.0 0.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.11 AEO69038.1 - 0.41 10.8 2.3 0.77 10.0 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 FliJ PF02050.11 AEO69038.1 - 7.9 6.5 12.3 0.71 9.9 4.5 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein EB1 PF03271.12 AEO69040.1 - 3.8e-14 52.4 1.3 8.1e-14 51.3 0.9 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 AEO69040.1 - 2.9e-06 27.2 0.8 5.5e-06 26.3 0.5 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain Flavokinase PF01687.12 AEO69042.1 - 1e-08 35.0 0.0 2.5e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 Riboflavin kinase Glyco_hydro_61 PF03443.9 AEO69043.1 - 1.8e-25 90.0 0.0 2.3e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SHIPPO-rpt PF07004.7 AEO69043.1 - 1.3 10.0 4.5 29 5.7 0.1 3.7 3 0 0 3 3 3 0 Sperm-tail PG-rich repeat Glyco_hydro_61 PF03443.9 AEO69044.1 - 1.9e-61 207.6 0.1 2.8e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 AEO69044.1 - 6.8e-10 38.4 14.2 6.8e-10 38.4 9.9 3.2 3 1 0 3 3 3 1 Fungal cellulose binding domain Actino_peptide PF14408.1 AEO69045.1 - 0.26 11.2 0.1 0.26 11.2 0.1 3.3 3 0 0 3 3 3 0 Ribosomally synthesized peptide in actinomycetes SR-25 PF10500.4 AEO69045.1 - 0.72 9.2 15.0 0.42 10.0 1.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Man-6-P_recep PF02157.10 AEO69048.1 - 1.7e-10 40.4 0.0 2.4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 AEO69048.1 - 7.6e-07 28.9 0.4 0.0012 18.5 0.0 2.4 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 AEO69048.1 - 1.9e-06 27.3 0.2 1.9e-06 27.3 0.2 3.3 2 1 1 3 3 2 1 Autophagy-related protein 27 NrfD_2 PF14589.1 AEO69048.1 - 0.083 12.5 0.3 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 Polysulfide reductase DUF2722 PF10846.3 AEO69048.1 - 0.13 11.2 4.3 0.17 10.8 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Daxx PF03344.10 AEO69048.1 - 0.19 10.2 9.5 0.29 9.5 6.6 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 AEO69048.1 - 0.61 8.0 12.8 0.81 7.6 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 AEO69048.1 - 1.1 9.2 15.2 1.7 8.6 10.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Atrophin-1 PF03154.10 AEO69048.1 - 2.4 6.2 6.2 4.2 5.3 4.3 1.3 1 0 0 1 1 1 0 Atrophin-1 family FAM176 PF14851.1 AEO69048.1 - 3.2 7.4 6.2 12 5.5 4.3 2.0 1 0 0 1 1 1 0 FAM176 family YqfQ PF14181.1 AEO69048.1 - 6.5 6.7 7.2 12 5.8 5.0 1.4 1 0 0 1 1 1 0 YqfQ-like protein TRAP_alpha PF03896.11 AEO69048.1 - 7.6 5.4 8.5 13 4.6 5.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ERG4_ERG24 PF01222.12 AEO69049.1 - 8.2e-173 574.8 0.4 9.4e-173 574.6 0.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 AEO69049.1 - 5.5e-05 22.5 0.1 0.00016 21.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) LSM PF01423.17 AEO69050.1 - 9.7e-17 60.2 0.1 1.4e-16 59.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain Glyco_hydro_3 PF00933.16 AEO69052.1 - 8.4e-93 310.6 0.0 1.4e-92 309.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO69052.1 - 9.8e-57 192.0 1.3 2.3e-56 190.8 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO69052.1 - 1.2e-14 54.0 0.0 2.8e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Acetyltransf_9 PF13527.1 AEO69053.1 - 0.0089 15.8 0.1 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO69053.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CorA PF01544.13 AEO69054.1 - 2.6e-06 26.7 0.1 3.9e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CCSMST1 PF15013.1 AEO69054.1 - 0.0061 16.4 1.6 0.015 15.2 0.3 2.2 2 1 1 3 3 3 1 CCSMST1 family DUF4010 PF13194.1 AEO69054.1 - 0.012 14.9 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) DUF4557 PF15101.1 AEO69056.1 - 0.0068 16.2 0.4 0.008 16.0 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) Pkinase PF00069.20 AEO69058.1 - 4e-11 42.5 0.0 2.5e-10 39.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Nucleoplasmin PF03066.10 AEO69058.1 - 0.6 9.6 3.3 0.94 8.9 2.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin Baculo_PEP_C PF04513.7 AEO69059.1 - 0.047 13.5 0.1 0.17 11.7 0.1 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 AEO69059.1 - 0.054 13.7 0.2 0.18 12.0 0.1 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein HemX PF04375.9 AEO69059.1 - 0.068 11.7 0.3 0.093 11.3 0.2 1.3 1 0 0 1 1 1 0 HemX HR1 PF02185.11 AEO69059.1 - 0.089 12.5 0.4 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Hr1 repeat Spc7 PF08317.6 AEO69059.1 - 0.1 11.2 0.3 0.12 10.9 0.2 1.2 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF2730 PF10805.3 AEO69059.1 - 0.12 12.1 0.1 2.1 8.1 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) CCDC-167 PF15188.1 AEO69060.1 - 0.039 13.9 0.6 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Peptidase_M6 PF05547.6 AEO69061.1 - 8.8e-22 76.8 3.7 9.3e-22 76.8 0.6 2.1 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 MFS_1 PF07690.11 AEO69062.1 - 3.4e-18 65.4 16.6 3.4e-18 65.4 11.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily SID-1_RNA_chan PF13965.1 AEO69062.1 - 0.055 11.6 5.1 0.085 11.0 3.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SnoaL PF07366.7 AEO69063.1 - 9.5e-06 25.2 0.2 3.5e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 AEO69063.1 - 7.3e-05 23.1 0.1 0.00018 21.8 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain PIP5K PF01504.13 AEO69064.1 - 5.1e-32 110.9 0.0 6.9e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Motile_Sperm PF00635.21 AEO69065.1 - 0.0083 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PALP PF00291.20 AEO69066.1 - 8.5e-61 205.8 0.1 1.2e-60 205.3 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 AEO69066.1 - 2.7e-08 33.4 0.0 9.2e-06 25.3 0.0 2.7 2 0 0 2 2 2 2 CBS domain SRPRB PF09439.5 AEO69067.1 - 3.6e-22 78.4 0.0 3.9e-14 52.2 0.0 3.2 3 0 0 3 3 3 3 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AEO69067.1 - 0.00012 21.9 0.0 0.00023 21.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 AEO69067.1 - 0.0007 19.6 3.5 0.0083 16.1 2.4 2.3 1 1 0 1 1 1 1 AAA ATPase domain Arf PF00025.16 AEO69067.1 - 0.0064 15.7 0.0 0.55 9.4 0.0 2.5 2 1 0 2 2 2 1 ADP-ribosylation factor family SRP54 PF00448.17 AEO69067.1 - 0.021 14.2 0.0 0.042 13.2 0.0 1.4 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 AEO69067.1 - 0.034 14.2 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AEO69067.1 - 0.048 12.7 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF258 PF03193.11 AEO69067.1 - 0.049 12.8 0.1 0.15 11.2 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 AEO69067.1 - 0.054 13.0 0.1 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 AEO69067.1 - 0.054 13.7 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA PF00004.24 AEO69067.1 - 0.061 13.5 0.0 2.5 8.2 0.1 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 AEO69067.1 - 0.19 11.1 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ank PF00023.25 AEO69068.1 - 1.8e-37 125.2 0.2 2.6e-08 33.2 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat zf-DHHC PF01529.15 AEO69068.1 - 7.7e-36 123.0 10.7 1.5e-35 122.1 7.4 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_2 PF12796.2 AEO69068.1 - 1.8e-35 121.1 0.0 1.2e-17 63.9 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 AEO69068.1 - 1.4e-27 95.0 0.1 6.2e-08 32.6 0.0 5.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO69068.1 - 2.2e-26 91.6 4.8 2.2e-07 31.1 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO69068.1 - 5.5e-25 84.9 0.5 8.2e-08 31.7 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Rad51 PF08423.6 AEO69069.1 - 0.035 13.0 0.0 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Rad51 zf-CCCH PF00642.19 AEO69069.1 - 7.3 6.3 12.4 6 6.6 1.3 2.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4131 PF13567.1 AEO69070.1 - 0.042 13.2 0.2 0.66 9.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Acyl_transf_3 PF01757.17 AEO69071.1 - 1.9e-36 125.5 33.0 2.7e-36 125.0 22.9 1.2 1 0 0 1 1 1 1 Acyltransferase family adh_short PF00106.20 AEO69072.1 - 3.5e-16 59.5 0.2 5.4e-16 58.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO69072.1 - 2.8e-08 33.6 0.2 8.4e-07 28.8 0.0 2.1 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 AEO69072.1 - 2e-05 24.1 0.0 2.8e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3940 PF13076.1 AEO69072.1 - 0.032 13.7 0.3 0.06 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3940) NAD_binding_10 PF13460.1 AEO69072.1 - 0.033 14.1 0.1 0.15 12.0 0.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding Herpes_capsid PF06112.6 AEO69073.1 - 0.52 10.3 12.6 0.89 9.5 8.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF4614 PF15391.1 AEO69073.1 - 2 8.1 9.4 3.7 7.2 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) UDPG_MGDP_dh_N PF03721.9 AEO69078.1 - 5.8e-39 133.3 0.1 4.8e-33 114.0 0.0 2.3 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 AEO69078.1 - 2.3e-24 85.4 0.0 4.6e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 AEO69078.1 - 1.6e-21 76.4 0.0 3.3e-16 59.3 0.0 3.3 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 AEO69078.1 - 0.0068 16.1 0.1 0.06 13.0 0.1 2.4 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glyco_tranf_2_3 PF13641.1 AEO69079.1 - 3e-29 102.4 1.0 4.1e-29 101.9 0.7 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 AEO69079.1 - 5.9e-20 71.6 0.0 9.6e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 AEO69079.1 - 2.5e-18 65.9 0.0 4.1e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 AEO69079.1 - 3.2e-16 59.6 6.8 3.2e-16 59.6 4.7 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_hydro_12 PF01670.11 AEO69079.1 - 5.4e-12 45.7 0.2 1.1e-11 44.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Cellulose_synt PF03552.9 AEO69079.1 - 5.5e-05 21.6 0.2 0.018 13.3 0.0 2.3 2 0 0 2 2 2 2 Cellulose synthase Glyco_tranf_2_2 PF10111.4 AEO69079.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 FA_desaturase PF00487.19 AEO69079.1 - 0.81 9.0 9.8 0.61 9.4 0.1 2.7 2 1 0 2 2 2 0 Fatty acid desaturase Pkinase PF00069.20 AEO69081.1 - 6e-23 81.3 0.0 8e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO69081.1 - 1.9e-11 43.5 0.0 1.3e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 AEO69081.1 - 0.026 13.5 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PBP_GOBP PF01395.17 AEO69081.1 - 0.027 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 PBP/GOBP family APH PF01636.18 AEO69081.1 - 0.065 12.9 0.1 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family NicO PF03824.11 AEO69082.1 - 7.7e-62 209.1 5.3 2.3e-61 207.5 3.7 1.8 1 1 0 1 1 1 1 High-affinity nickel-transport protein Zn_clus PF00172.13 AEO69083.1 - 1.8e-07 30.9 6.9 1.8e-07 30.9 4.8 2.6 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 AEO69083.1 - 4.8e-06 26.5 19.9 0.0011 19.1 2.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO69083.1 - 4.5e-05 23.5 14.6 0.027 14.8 1.9 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO69083.1 - 0.00078 19.6 2.6 0.00078 19.6 1.8 3.2 3 0 0 3 3 3 1 Zinc-finger double domain Fungal_trans PF04082.13 AEO69083.1 - 0.0016 17.4 0.3 0.013 14.3 0.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Tmemb_55A PF09788.4 AEO69083.1 - 0.052 12.6 1.7 0.097 11.7 1.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 55A p450 PF00067.17 AEO69084.1 - 1.3e-63 215.1 0.0 2e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 AEO69086.1 - 1.1e-16 60.8 1.1 4.9e-08 32.4 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 AEO69086.1 - 0.025 14.6 0.1 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO69086.1 - 0.088 11.6 0.0 0.58 8.9 0.0 2.1 2 1 0 2 2 2 0 FAD dependent oxidoreductase TPR_12 PF13424.1 AEO69088.1 - 6.1e-55 183.1 12.0 1.8e-15 56.6 0.5 4.6 3 1 2 5 5 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 AEO69088.1 - 1.2e-50 168.0 14.1 2.4e-08 33.6 0.2 7.2 7 0 0 7 7 6 6 Tetratricopeptide repeat Patatin PF01734.17 AEO69088.1 - 2.7e-25 89.5 0.4 6.3e-25 88.3 0.1 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase TPR_1 PF00515.23 AEO69088.1 - 5.8e-23 79.4 4.5 0.00082 18.8 0.1 6.9 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 AEO69088.1 - 6.8e-17 60.8 1.0 6.1e-05 22.5 0.1 4.2 3 1 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 AEO69088.1 - 1.2e-15 56.0 4.9 0.012 15.4 0.1 7.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 AEO69088.1 - 5.2e-15 53.9 9.6 0.002 17.8 0.1 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 AEO69088.1 - 1.5e-09 37.6 20.3 0.048 14.3 0.2 7.7 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 AEO69088.1 - 2.3e-09 36.3 1.6 2.3 8.1 0.0 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 AEO69088.1 - 7.9e-09 35.1 0.1 1.5 9.4 0.0 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO69088.1 - 1.2e-08 35.4 8.3 0.088 13.5 0.9 6.4 3 2 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 AEO69088.1 - 1.3e-08 35.0 3.9 0.083 13.2 0.0 5.1 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 AEO69088.1 - 2.3e-06 27.3 1.4 2.5 8.5 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat NB-ARC PF00931.17 AEO69088.1 - 3.6e-05 22.7 0.0 9.2e-05 21.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain PPR PF01535.15 AEO69088.1 - 0.00016 21.4 0.5 5.7 7.1 0.0 5.5 6 0 0 6 6 6 1 PPR repeat AAA_16 PF13191.1 AEO69088.1 - 0.00021 21.3 2.4 0.0011 19.0 1.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AEO69088.1 - 0.00091 19.3 0.0 0.0037 17.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain Arch_ATPase PF01637.13 AEO69088.1 - 0.0031 17.2 0.0 0.0078 15.9 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase TPR_6 PF13174.1 AEO69088.1 - 0.27 11.7 19.1 11 6.7 0.1 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat adh_short PF00106.20 AEO69089.1 - 1.6e-26 93.1 1.1 2.5e-26 92.5 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO69089.1 - 4.5e-16 59.3 0.0 6.1e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO69089.1 - 1.2e-12 47.9 0.3 2.5e-12 46.8 0.1 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 AEO69089.1 - 2.4e-07 30.9 0.1 4.1e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 AEO69089.1 - 0.00023 20.4 0.0 0.0003 20.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 AEO69089.1 - 0.00048 19.8 0.0 0.0015 18.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RFX_DNA_binding PF02257.10 AEO69089.1 - 0.061 13.4 0.0 0.23 11.6 0.0 2.0 3 0 0 3 3 3 0 RFX DNA-binding domain F420_oxidored PF03807.12 AEO69089.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Nha1_C PF08619.5 AEO69090.1 - 1.5e-91 307.9 29.3 4e-87 293.2 10.8 2.7 2 1 0 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 AEO69090.1 - 3.3e-69 233.2 21.7 4e-69 232.9 15.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF21 PF01595.15 AEO69090.1 - 0.068 12.4 11.6 0.1 11.9 2.2 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF21 YjeF_N PF03853.10 AEO69091.1 - 5.9e-42 143.1 0.0 8.7e-42 142.5 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 AEO69091.1 - 8.6e-10 39.0 0.0 2.2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 FDF domain CAP59_mtransfer PF11735.3 AEO69092.1 - 2.6e-61 206.9 0.0 5.5e-61 205.8 0.0 1.5 2 0 0 2 2 2 1 Cryptococcal mannosyltransferase 1 Lactamase_B_2 PF12706.2 AEO69093.1 - 6.4e-11 42.1 0.0 8.5e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AEO69093.1 - 2e-07 30.8 0.7 3.9e-07 29.8 0.4 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Amidohydro_2 PF04909.9 AEO69093.1 - 0.0063 16.1 1.7 0.093 12.2 0.0 2.6 1 1 0 2 2 2 1 Amidohydrolase tRNA-synt_1g PF09334.6 AEO69094.1 - 2.1e-136 454.6 0.0 1.5e-135 451.8 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 AEO69094.1 - 5.5e-07 27.9 5.7 0.0019 16.2 0.0 4.3 4 1 1 5 5 5 4 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AEO69094.1 - 0.06 13.0 0.4 0.15 11.8 0.2 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA DUF1682 PF07946.9 AEO69094.1 - 0.7 8.6 12.0 1.1 8.0 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CRCB PF02537.10 AEO69096.1 - 1e-29 102.7 14.2 1.4e-16 60.3 8.3 3.3 3 0 0 3 3 3 3 CrcB-like protein UPRTase PF14681.1 AEO69097.1 - 6.8e-73 244.2 0.0 7.8e-73 244.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 AEO69097.1 - 1.7e-05 24.5 0.1 0.00011 21.9 0.1 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.12 AEO69097.1 - 0.089 11.9 0.3 0.44 9.6 0.1 1.9 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI DNA_ligase_A_M PF01068.16 AEO69098.1 - 3.5e-44 150.6 0.0 5.5e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 AEO69098.1 - 9.8e-36 123.2 0.0 1.8e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 AEO69098.1 - 5.6e-16 58.7 0.6 1.7e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 AEO69098.1 - 3.6e-08 33.4 0.0 6.4e-07 29.4 0.0 2.6 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 AEO69098.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 DNA ligase IV mRNA_cap_enzyme PF01331.14 AEO69098.1 - 0.029 14.0 0.0 0.45 10.1 0.0 2.5 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain DUF4449 PF14613.1 AEO69099.1 - 6e-64 214.9 0.0 6e-64 214.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Prp18 PF02840.10 AEO69099.1 - 0.06 13.1 0.7 3.5 7.4 0.0 2.6 1 1 1 2 2 2 0 Prp18 domain Lipin_N PF04571.9 AEO69099.1 - 0.087 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 lipin, N-terminal conserved region APH PF01636.18 AEO69100.1 - 6.5e-19 68.6 0.0 1.1e-18 67.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO69100.1 - 0.022 14.3 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DOT1 PF08123.8 AEO69101.1 - 1.6e-74 249.6 0.0 6.6e-74 247.6 0.0 1.8 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 AEO69101.1 - 1.9e-05 24.6 0.1 4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO69101.1 - 4.8e-05 23.0 0.0 7.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO69101.1 - 0.00014 22.3 0.2 0.00059 20.3 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain DUF1129 PF06570.6 AEO69101.1 - 0.16 11.2 0.1 0.26 10.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Nucleo_P87 PF07267.6 AEO69101.1 - 2 7.0 4.8 3 6.4 3.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ATG16 PF08614.6 AEO69102.1 - 1.6e-44 152.1 8.7 1.8e-44 151.9 6.0 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) SecD-TM1 PF13721.1 AEO69102.1 - 0.49 10.6 4.7 0.17 12.1 1.2 1.8 2 0 0 2 2 2 0 SecD export protein N-terminal TM region ALIX_LYPXL_bnd PF13949.1 AEO69102.1 - 0.52 9.2 15.8 6.3 5.6 8.6 2.7 2 1 0 2 2 2 0 ALIX V-shaped domain binding to HIV UPF0242 PF06785.6 AEO69102.1 - 1.9 7.0 7.1 2.6 6.6 5.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Atg14 PF10186.4 AEO69102.1 - 3.1 6.6 14.0 5.3 5.8 9.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4061 PF13270.1 AEO69102.1 - 3.5 7.7 9.6 2.2 8.4 2.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4061) DUF904 PF06005.7 AEO69102.1 - 4.6 7.6 19.4 5.2 7.4 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Vps16_N PF04841.8 AEO69103.1 - 4.1e-99 331.9 0.0 5.7e-99 331.4 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 AEO69103.1 - 5.2e-74 249.0 0.0 7.5e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region DUF4652 PF15525.1 AEO69103.1 - 0.088 12.2 0.0 5.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4652) FHA PF00498.21 AEO69104.1 - 3.5e-16 59.0 0.0 6.9e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 AEO69104.1 - 1.2e-05 25.0 12.3 1.9e-05 24.4 8.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AEO69104.1 - 0.00076 19.5 5.1 0.0013 18.7 3.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 AEO69104.1 - 0.09 12.4 12.6 0.14 11.8 8.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 AEO69104.1 - 0.092 12.4 7.3 0.16 11.6 5.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-Apc11 PF12861.2 AEO69104.1 - 0.16 11.7 2.5 0.28 11.0 1.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 AEO69104.1 - 0.63 9.8 9.9 1 9.1 6.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.6 AEO69104.1 - 0.76 9.8 8.2 1.3 9.1 5.7 1.3 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.1 AEO69104.1 - 3.7 7.6 14.2 6.1 6.9 9.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M16_C PF05193.16 AEO69105.1 - 3.1e-57 193.2 0.0 7.2e-57 192.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AEO69105.1 - 1.3e-42 145.0 0.0 2.6e-42 144.0 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) S1 PF00575.18 AEO69107.1 - 2.8e-101 331.7 30.4 4e-18 65.2 0.1 13.4 13 0 0 13 13 13 11 S1 RNA binding domain TPR_19 PF14559.1 AEO69107.1 - 8e-08 32.5 0.9 0.0051 17.1 0.0 4.0 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 AEO69107.1 - 1.3e-05 25.4 14.9 0.076 13.6 0.0 5.8 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO69107.1 - 5e-05 23.8 10.2 0.0019 18.8 0.0 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 AEO69107.1 - 0.00013 21.5 0.1 0.0051 16.4 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 AEO69107.1 - 0.00023 20.8 0.2 0.018 14.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 AEO69107.1 - 0.00026 20.8 0.6 0.0024 17.7 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 AEO69107.1 - 0.00041 20.6 2.1 0.78 10.3 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 AEO69107.1 - 0.0019 18.2 0.2 6.5 7.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 AEO69107.1 - 0.0026 17.4 0.0 0.065 13.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Suf PF05843.9 AEO69107.1 - 0.016 14.9 8.8 0.67 9.6 0.1 4.0 3 1 1 4 4 4 0 Suppressor of forked protein (Suf) NRDE-2 PF08424.5 AEO69107.1 - 0.018 13.9 0.4 0.68 8.7 0.3 2.6 2 1 1 3 3 3 0 NRDE-2, necessary for RNA interference Ras_bdg_2 PF14847.1 AEO69107.1 - 0.019 14.8 0.6 7.6 6.5 0.0 3.2 3 1 1 4 4 3 0 Ras-binding domain of Byr2 TPR_8 PF13181.1 AEO69107.1 - 0.05 13.4 0.1 0.22 11.3 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat PPR PF01535.15 AEO69107.1 - 0.25 11.4 0.0 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 PPR repeat MAP65_ASE1 PF03999.7 AEO69112.1 - 1e-72 245.7 8.4 2.6e-72 244.3 5.6 1.4 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) MFS_1 PF07690.11 AEO69113.1 - 1.3e-48 165.5 30.5 1.3e-48 165.5 21.2 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO69113.1 - 1.7e-11 43.3 32.2 4.2e-11 42.1 8.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 AEO69113.1 - 7.2e-05 21.0 5.7 7.2e-05 21.0 4.0 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector DUF3353 PF11833.3 AEO69113.1 - 9.2 5.6 17.2 0.11 11.8 5.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) EF-hand_4 PF12763.2 AEO69114.1 - 5.5e-06 26.0 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Lactococcin PF04369.8 AEO69116.1 - 4.1 7.4 5.8 0.84 9.5 0.2 2.6 3 0 0 3 3 3 0 Lactococcin-like family ABA_GPCR PF12430.3 AEO69117.1 - 6.4e-52 175.5 0.0 1.3e-51 174.5 0.0 1.5 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 AEO69117.1 - 5.1e-19 68.1 0.1 5.1e-18 64.8 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3735) Usp PF00582.21 AEO69118.1 - 1.7e-11 44.4 0.7 5.7e-11 42.7 0.0 2.2 2 1 0 2 2 2 1 Universal stress protein family Paf67 PF10255.4 AEO69119.1 - 2e-154 514.3 0.1 2.4e-154 514.1 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 AEO69119.1 - 0.014 15.2 0.3 0.11 12.4 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat GTP_EFTU PF00009.22 AEO69120.1 - 1.8e-32 112.3 0.0 2.7e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 AEO69120.1 - 3.4e-15 55.6 0.0 8.8e-15 54.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AEO69120.1 - 5.2e-10 39.2 0.0 1.4e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 AEO69120.1 - 4.2e-08 32.9 0.0 1.2e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 AEO69120.1 - 8e-08 31.8 0.0 7.5e-05 22.2 0.0 3.1 3 0 0 3 3 3 2 Elongation factor G, domain IV RRM_6 PF14259.1 AEO69121.1 - 1.4e-12 47.4 0.0 2.6e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO69121.1 - 3.1e-11 42.7 0.0 6.8e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO69121.1 - 0.00091 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.6 AEO69121.1 - 0.016 15.1 15.0 0.024 14.5 10.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Mitofilin PF09731.4 AEO69121.1 - 0.035 12.7 14.1 0.044 12.4 9.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HC2 PF07382.6 AEO69121.1 - 0.57 10.0 28.3 0.92 9.3 19.6 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 DUF1510 PF07423.6 AEO69121.1 - 5.6 6.2 14.7 8.7 5.6 10.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SAPS PF04499.10 AEO69121.1 - 7.1 5.1 5.6 9.4 4.7 3.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tim17 PF02466.14 AEO69122.1 - 0.25 11.3 5.4 1.4 8.9 3.7 2.0 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family DUF1183 PF06682.7 AEO69123.1 - 0.0036 16.9 2.0 0.0036 16.9 1.4 2.5 1 1 0 2 2 2 1 Protein of unknown function (DUF1183) Rax2 PF12768.2 AEO69123.1 - 0.041 13.0 0.1 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DNA_pol_viral_N PF00242.12 AEO69123.1 - 0.3 10.0 4.4 0.36 9.7 3.1 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 AEO69123.1 - 1.6 6.8 8.2 2 6.6 5.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Fmp27 PF10344.4 AEO69124.1 - 4.3e-246 818.8 0.0 5.9e-246 818.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 AEO69124.1 - 5.7e-174 579.2 0.0 1.1e-173 578.3 0.0 1.5 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 AEO69124.1 - 2.5e-152 507.6 0.0 1.2e-151 505.3 0.0 2.0 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 AEO69124.1 - 9.9e-56 187.9 0.0 2.1e-55 186.8 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 AEO69124.1 - 3.1e-54 183.0 0.2 7.8e-54 181.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 AEO69124.1 - 1e-33 115.8 0.0 3.7e-33 114.0 0.0 2.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain JAB PF01398.16 AEO69125.1 - 1.6e-22 79.4 0.0 2.5e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 AEO69125.1 - 2.4e-06 27.0 0.0 6.8e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain tRNA-synt_1c PF00749.16 AEO69127.1 - 2e-64 217.2 0.0 2.6e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ PF00226.26 AEO69128.1 - 7.4e-25 86.4 1.7 2.6e-24 84.7 1.3 1.9 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 AEO69128.1 - 6.1e-20 70.9 0.0 4.3e-18 64.9 0.0 2.6 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AEO69128.1 - 1.2e-13 50.9 15.0 1.8e-13 50.2 10.4 1.3 1 0 0 1 1 1 1 DnaJ central domain UreE_N PF02814.10 AEO69128.1 - 0.0013 18.1 0.1 0.0028 17.1 0.1 1.5 1 0 0 1 1 1 1 UreE urease accessory protein, N-terminal domain HypA PF01155.14 AEO69128.1 - 0.0015 18.2 3.3 0.36 10.5 0.5 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Val_tRNA-synt_C PF10458.4 AEO69128.1 - 0.063 13.3 0.4 0.16 12.1 0.2 1.7 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm DUF1356 PF07092.7 AEO69128.1 - 0.081 12.1 2.8 0.51 9.4 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) APP_E2 PF12925.2 AEO69128.1 - 0.095 12.2 0.5 0.15 11.6 0.4 1.2 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein DZR PF12773.2 AEO69128.1 - 1.2 9.0 8.9 2.8 7.8 0.9 2.5 2 0 0 2 2 2 0 Double zinc ribbon Ribosomal_L32e PF01655.13 AEO69129.1 - 5e-51 171.3 1.8 6.8e-51 170.9 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 Aminotran_5 PF00266.14 AEO69130.1 - 1.9e-13 49.9 0.0 7.9e-13 47.8 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 AEO69130.1 - 0.00022 19.6 0.2 0.0015 16.9 0.1 1.9 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 AEO69130.1 - 0.00046 19.3 0.0 0.00084 18.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 AEO69130.1 - 0.073 12.0 0.0 0.27 10.1 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class I and II RVT_1 PF00078.22 AEO69132.1 - 0.011 15.0 0.2 0.015 14.6 0.2 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_1 PF01344.20 AEO69132.1 - 0.11 12.1 0.0 0.38 10.3 0.0 1.9 2 0 0 2 2 2 0 Kelch motif ELFV_dehydrog PF00208.16 AEO69133.1 - 7.9e-61 205.7 0.0 1.6e-60 204.6 0.0 1.6 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 AEO69133.1 - 6e-23 80.3 0.0 3.3e-17 61.3 0.0 2.5 2 1 1 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 AEO69133.1 - 0.00026 20.5 0.1 0.0015 18.1 0.0 2.3 3 0 0 3 3 3 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF1325 PF07039.6 AEO69133.1 - 0.094 12.3 0.3 2.5 7.6 0.0 3.0 3 0 0 3 3 3 0 SGF29 tudor-like domain PDH PF02153.12 AEO69134.1 - 4.4e-17 61.8 0.0 6.2e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 AEO69134.1 - 6.2e-08 32.6 0.0 1.7e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AEO69134.1 - 2.1e-07 31.2 0.0 5.1e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 AEO69134.1 - 2.6e-05 23.4 0.0 5.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 AEO69134.1 - 0.0011 19.0 0.1 0.0024 17.9 0.0 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 AEO69134.1 - 0.0063 16.1 0.0 0.027 14.1 0.0 2.0 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.4 AEO69134.1 - 0.0072 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Rossmann-like domain ApbA PF02558.11 AEO69134.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 AEO69134.1 - 0.015 15.2 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain RCC1 PF00415.13 AEO69135.1 - 1.4e-29 102.0 25.4 8e-10 38.7 0.1 7.2 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AEO69135.1 - 4.8e-23 80.1 39.1 2.3e-08 33.4 0.6 6.8 9 0 0 9 9 9 4 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.8 AEO69136.1 - 2.2e-75 253.0 0.0 2.7e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 Rad9 Alk_phosphatase PF00245.15 AEO69138.1 - 6e-105 351.3 0.0 7.3e-105 351.0 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 AEO69138.1 - 0.00016 21.1 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Abhydrolase_6 PF12697.2 AEO69139.1 - 4.4e-25 88.8 2.1 7.1e-25 88.2 1.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO69139.1 - 4.3e-16 58.9 0.0 9e-16 57.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO69139.1 - 2.1e-10 40.5 0.0 7.3e-09 35.5 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.15 AEO69139.1 - 3.3e-10 39.6 0.0 6.8e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.15 AEO69139.1 - 4.2e-05 23.8 0.0 7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 AEO69139.1 - 0.003 17.1 0.4 0.008 15.7 0.1 1.8 1 1 1 2 2 2 1 Lipase (class 3) DUF2305 PF10230.4 AEO69139.1 - 0.0058 16.0 0.0 0.013 14.9 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 AEO69139.1 - 0.0086 15.6 0.2 0.06 12.9 0.2 2.0 1 1 0 1 1 1 1 PGAP1-like protein FSH1 PF03959.8 AEO69139.1 - 0.011 15.2 0.0 0.86 9.0 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) LCAT PF02450.10 AEO69139.1 - 0.015 14.2 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.8 AEO69139.1 - 0.016 14.7 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 AEO69139.1 - 0.023 14.1 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PTPlike_phytase PF14566.1 AEO69139.1 - 0.038 14.0 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 AEO69139.1 - 0.044 13.1 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF900 PF05990.7 AEO69139.1 - 0.13 11.5 0.0 0.35 10.1 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1640 PF07798.6 AEO69140.1 - 1.3e-12 48.1 1.7 1.7e-12 47.7 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HEAT_2 PF13646.1 AEO69141.1 - 3.7e-14 52.7 13.3 0.00046 20.4 0.0 8.0 6 2 2 8 8 8 5 HEAT repeats HEAT PF02985.17 AEO69141.1 - 3.1e-11 42.3 21.2 0.038 14.0 0.0 11.0 11 0 0 11 11 11 5 HEAT repeat Vac14_Fab1_bd PF12755.2 AEO69141.1 - 8e-09 35.7 0.4 0.027 14.8 0.0 5.5 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region ICMT PF04140.9 AEO69141.1 - 0.016 15.4 0.1 0.27 11.4 0.0 2.6 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Resolvase PF00239.16 AEO69141.1 - 0.31 10.8 0.9 10 5.9 0.0 3.3 3 0 0 3 3 3 0 Resolvase, N terminal domain Transcrip_reg PF01709.15 AEO69142.1 - 2e-62 210.3 0.3 2.3e-62 210.1 0.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator dCMP_cyt_deam_2 PF08211.6 AEO69142.1 - 0.0034 17.3 0.2 0.0063 16.5 0.1 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF2346 PF09803.4 AEO69143.1 - 0.00014 21.6 3.3 0.0003 20.5 2.3 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) Glyco_transf_22 PF03901.12 AEO69144.1 - 3.5e-51 174.5 7.8 1e-27 97.2 0.1 2.0 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family Skp1 PF01466.14 AEO69145.1 - 4.7e-40 135.4 2.1 8.3e-40 134.6 1.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 AEO69145.1 - 3e-21 75.2 0.0 7.5e-21 73.9 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain UPF0052 PF01933.13 AEO69145.1 - 0.0072 15.6 0.2 0.012 14.9 0.0 1.4 2 0 0 2 2 2 1 Uncharacterised protein family UPF0052 DUF4375 PF14300.1 AEO69145.1 - 0.037 14.0 0.9 0.068 13.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) BTB PF00651.26 AEO69145.1 - 0.081 12.9 0.0 1.2 9.1 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain Ribosomal_L39 PF00832.15 AEO69146.1 - 5.6e-22 76.9 10.1 6.4e-22 76.7 7.0 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Selenoprotein_S PF06936.6 AEO69146.1 - 0.12 11.8 0.8 0.14 11.6 0.5 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) Ribosomal_L13e PF01294.13 AEO69146.1 - 0.24 10.8 2.6 0.24 10.8 1.8 1.0 1 0 0 1 1 1 0 Ribosomal protein L13e Arf PF00025.16 AEO69147.1 - 4.3e-74 247.5 0.0 4.9e-74 247.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AEO69147.1 - 1.9e-12 46.7 0.0 2.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 AEO69147.1 - 1.6e-11 43.5 0.5 1.7e-07 30.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 AEO69147.1 - 2.7e-10 39.8 0.0 3.2e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO69147.1 - 8.5e-09 35.9 0.0 1.2e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 AEO69147.1 - 1.2e-08 34.4 0.0 1.6e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AEO69147.1 - 2.1e-06 27.6 0.0 2.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AEO69147.1 - 2e-05 24.1 0.1 0.0027 17.1 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 AEO69147.1 - 0.0015 17.3 0.4 0.0052 15.5 0.1 2.0 2 1 0 2 2 2 1 ArgK protein FeoB_N PF02421.13 AEO69147.1 - 0.023 13.9 0.9 0.12 11.6 0.6 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B tRNA-synt_2d PF01409.15 AEO69148.1 - 1.6e-85 286.2 0.0 8.9e-85 283.8 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 AEO69148.1 - 8.6e-09 34.6 0.5 0.0006 18.6 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 AEO69148.1 - 0.0003 20.4 0.0 0.005 16.4 0.0 2.4 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) WWbp PF10349.4 AEO69149.1 - 0.44 11.4 4.2 0.64 10.9 2.9 1.2 1 0 0 1 1 1 0 WW-domain ligand protein PTPLA PF04387.9 AEO69150.1 - 7.6e-28 96.9 16.4 1.8e-27 95.8 7.8 2.6 2 1 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA PGAP1 PF07819.8 AEO69151.1 - 6.3e-06 25.9 0.1 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 AEO69151.1 - 1.6e-05 24.6 0.7 4.4e-05 23.2 0.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO69151.1 - 0.00014 21.7 1.6 0.00023 21.1 1.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 AEO69151.1 - 0.00052 19.6 0.0 0.014 15.0 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 AEO69151.1 - 0.0037 17.5 0.0 0.0082 16.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.9 AEO69151.1 - 0.0045 16.3 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 AEO69151.1 - 0.0062 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.11 AEO69151.1 - 0.077 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2305 PF10230.4 AEO69151.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) PAP_central PF04928.12 AEO69152.1 - 3.4e-102 340.6 0.1 1.1e-101 338.8 0.0 1.8 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 AEO69152.1 - 1.5e-45 154.5 0.0 4.9e-45 152.8 0.0 1.8 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 AEO69152.1 - 2.5e-07 30.9 0.2 1.1e-06 28.9 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain Tubulin_3 PF14881.1 AEO69153.1 - 4.7e-64 215.1 0.0 8.7e-64 214.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 AEO69153.1 - 1.6e-39 134.5 0.0 3.4e-39 133.4 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 AEO69153.1 - 5.7e-07 29.5 0.0 0.0058 16.4 0.0 2.4 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Pyr_redox_2 PF07992.9 AEO69154.1 - 2.8e-26 92.6 0.0 2.5e-25 89.5 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO69154.1 - 2.5e-13 50.2 0.0 2e-12 47.3 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO69154.1 - 0.00039 20.5 0.1 1.4 8.9 0.1 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Herpes_capsid PF06112.6 AEO69156.1 - 3.5 7.6 6.8 4.2 7.4 4.7 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Na_H_Exchanger PF00999.16 AEO69157.1 - 1e-68 231.6 39.6 1.2e-68 231.3 27.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MFS_2 PF13347.1 AEO69158.1 - 2.1e-10 39.6 5.4 2.1e-10 39.6 3.7 3.1 3 0 0 3 3 3 3 MFS/sugar transport protein Polysacc_lyase PF14099.1 AEO69159.1 - 0.0043 16.7 5.9 0.0065 16.1 4.1 1.3 1 0 0 1 1 1 1 Polysaccharide lyase SH3_1 PF00018.23 AEO69160.1 - 0.0072 15.6 0.2 0.03 13.6 0.0 2.1 2 0 0 2 2 2 1 SH3 domain Serinc PF03348.10 AEO69160.1 - 5.7 5.5 9.6 10 4.6 6.6 1.4 1 1 0 1 1 1 0 Serine incorporator (Serinc) PalH PF08733.5 AEO69161.1 - 3.5e-110 368.1 0.0 4.2e-110 367.8 0.0 1.0 1 0 0 1 1 1 1 PalH/RIM21 SPC25 PF06703.6 AEO69161.1 - 1.2 8.7 3.8 4.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF765 PF05570.6 AEO69162.1 - 4.3 7.3 5.9 11 6.1 0.6 2.4 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF765) TRAM_LAG1_CLN8 PF03798.11 AEO69163.1 - 1.8e-34 119.0 19.4 1.8e-34 119.0 13.5 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 AEO69163.1 - 4.8e-24 83.6 0.0 1.3e-23 82.2 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein ABC_tran PF00005.22 AEO69164.1 - 5.1e-31 107.8 0.0 1.2e-30 106.5 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 AEO69164.1 - 2.9e-26 92.5 4.9 5.7e-26 91.5 3.4 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 AEO69164.1 - 0.0001 21.6 0.0 0.00055 19.2 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AEO69164.1 - 0.0061 16.5 0.0 0.38 10.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 AEO69164.1 - 0.012 15.5 0.1 0.14 12.0 0.1 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 AEO69164.1 - 0.015 14.4 0.0 0.044 12.9 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 AEO69164.1 - 0.025 14.1 0.1 0.058 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 AEO69167.1 - 1.6e-98 326.0 0.0 9e-48 161.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AEO69167.1 - 2.2e-19 69.1 1.3 5.5e-19 67.9 0.4 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 AEO69167.1 - 6.3e-14 51.5 0.0 3.5e-06 26.2 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 AEO69167.1 - 7.2e-14 52.0 0.0 1.8e-07 31.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 AEO69167.1 - 5e-13 48.9 0.5 9.3e-07 28.6 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AEO69167.1 - 1.6e-12 47.5 0.0 1.6e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 AEO69167.1 - 3.5e-12 46.5 0.3 0.00067 19.7 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AEO69167.1 - 8.3e-12 45.4 0.0 0.0003 20.8 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 AEO69167.1 - 2.7e-11 44.3 0.0 0.00033 21.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 AEO69167.1 - 2.7e-09 36.2 0.1 0.00085 18.1 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 AEO69167.1 - 4.4e-09 36.0 5.7 0.017 14.4 0.0 4.8 3 2 2 5 5 4 3 AAA domain AAA_14 PF13173.1 AEO69167.1 - 2e-08 34.2 0.0 0.0014 18.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 AEO69167.1 - 2.7e-08 33.4 0.0 0.0053 16.2 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 AEO69167.1 - 3.4e-08 33.1 1.8 0.0083 15.8 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain CDC48_2 PF02933.12 AEO69167.1 - 1.5e-07 30.9 0.0 4.3e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.16 AEO69167.1 - 1.7e-07 30.6 0.2 0.0057 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 AEO69167.1 - 1.9e-07 30.3 0.1 0.011 14.8 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin RNA_helicase PF00910.17 AEO69167.1 - 4.7e-07 29.9 0.0 0.026 14.6 0.0 2.9 3 0 0 3 3 2 2 RNA helicase KaiC PF06745.8 AEO69167.1 - 5.3e-07 28.9 0.8 0.22 10.5 0.0 3.5 2 1 1 3 3 3 2 KaiC DUF815 PF05673.8 AEO69167.1 - 1.1e-06 27.8 0.0 0.0059 15.5 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_18 PF13238.1 AEO69167.1 - 1.4e-06 28.6 0.0 0.086 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 AEO69167.1 - 2.2e-06 27.6 0.0 0.0021 17.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 AEO69167.1 - 2.2e-06 27.4 0.3 0.095 12.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 AEO69167.1 - 2.9e-06 27.3 0.1 0.089 12.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.12 AEO69167.1 - 7.7e-06 24.9 0.1 0.043 12.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 AEO69167.1 - 1e-05 25.6 0.0 0.045 13.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 AEO69167.1 - 1.2e-05 25.0 0.0 4.1 7.0 0.0 4.0 2 2 1 3 3 3 0 Archaeal ATPase Sigma54_activat PF00158.21 AEO69167.1 - 1.4e-05 24.6 0.1 0.16 11.4 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 AEO69167.1 - 1.5e-05 25.3 0.0 0.23 11.7 0.0 3.7 3 1 0 3 3 2 2 ABC transporter NACHT PF05729.7 AEO69167.1 - 1.5e-05 24.6 0.0 0.085 12.5 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Bac_DnaA PF00308.13 AEO69167.1 - 2.7e-05 23.9 0.0 0.15 11.6 0.0 3.0 3 0 0 3 3 3 2 Bacterial dnaA protein PhoH PF02562.11 AEO69167.1 - 0.00013 21.2 0.2 0.5 9.5 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 AEO69167.1 - 0.00017 21.1 0.0 0.57 9.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 AEO69167.1 - 0.00018 21.1 0.0 0.49 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 AEO69167.1 - 0.0003 20.4 0.0 0.59 9.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.5 AEO69167.1 - 0.00034 20.4 0.1 0.0014 18.4 0.0 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain NB-ARC PF00931.17 AEO69167.1 - 0.00048 19.0 0.1 0.55 9.0 0.0 2.8 3 0 0 3 3 2 2 NB-ARC domain NTPase_1 PF03266.10 AEO69167.1 - 0.00095 18.9 0.9 0.65 9.6 0.0 3.9 4 0 0 4 4 3 1 NTPase DUF2075 PF09848.4 AEO69167.1 - 0.0016 17.5 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 AEO69167.1 - 0.0054 15.7 0.3 1.1 8.2 0.0 3.5 2 2 1 4 4 4 1 KAP family P-loop domain Viral_helicase1 PF01443.13 AEO69167.1 - 0.0055 16.2 0.0 0.28 10.6 0.0 2.5 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase IPT PF01745.11 AEO69167.1 - 0.011 14.9 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 AEO69167.1 - 0.019 14.6 0.1 8.9 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 AEO69167.1 - 0.029 13.8 0.6 1.6 8.1 0.0 3.4 3 1 1 4 4 4 0 AAA-like domain T2SE PF00437.15 AEO69167.1 - 0.031 13.1 0.0 1.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Zot PF05707.7 AEO69167.1 - 0.038 13.4 0.1 13 5.2 0.1 3.9 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) AAA_23 PF13476.1 AEO69167.1 - 0.068 13.4 0.1 4.4 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 AEO69167.1 - 0.077 11.7 0.0 9.6 4.8 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase SKI PF01202.17 AEO69167.1 - 0.086 12.7 0.1 8.3 6.2 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase KTI12 PF08433.5 AEO69167.1 - 0.11 11.6 0.3 11 5.0 0.0 2.8 3 0 0 3 3 2 0 Chromatin associated protein KTI12 MobB PF03205.9 AEO69167.1 - 0.14 11.8 1.2 3.5 7.3 0.0 3.3 4 0 0 4 4 2 0 Molybdopterin guanine dinucleotide synthesis protein B RVT_1 PF00078.22 AEO69169.1 - 0.0087 15.4 0.8 0.011 15.0 0.6 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exonuc_V_gamma PF04257.9 AEO69169.1 - 0.095 10.6 0.9 0.11 10.4 0.6 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit Phosphoprotein PF00922.12 AEO69170.1 - 1.4 8.0 5.5 1.7 7.7 3.8 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein AhpC-TSA_2 PF13911.1 AEO69171.1 - 9.7e-08 31.9 0.0 1.9e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Fungal_trans_2 PF11951.3 AEO69171.1 - 1.4e-05 23.8 0.2 2.6e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_3 PF00202.16 AEO69172.1 - 6.9e-74 248.7 0.0 8.5e-74 248.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Fork_head PF00250.13 AEO69174.1 - 2.6e-33 113.9 0.2 4.4e-33 113.1 0.1 1.3 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 AEO69174.1 - 4e-06 26.8 0.0 7.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain CLU PF13236.1 AEO69175.1 - 2.5e-82 275.6 0.0 4.1e-82 274.8 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 AEO69175.1 - 1.7e-49 168.0 0.2 4.9e-49 166.5 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 AEO69175.1 - 6.8e-30 102.8 16.0 1.8e-10 40.5 0.1 3.6 1 1 3 4 4 4 4 Tetratricopeptide repeat CLU_N PF15044.1 AEO69175.1 - 2e-24 85.4 0.1 4.3e-24 84.4 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 AEO69175.1 - 3.3e-17 61.7 1.2 0.0007 19.4 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 AEO69175.1 - 1.7e-05 24.3 7.9 0.096 12.3 0.9 3.5 2 1 0 3 3 3 3 TPR repeat DUF727 PF05303.7 AEO69175.1 - 5.9e-05 22.8 0.0 0.00017 21.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.1 AEO69175.1 - 0.08 12.7 2.1 0.4 10.5 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 AEO69175.1 - 0.16 12.1 2.6 7.3 6.8 0.2 3.0 2 2 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 AEO69175.1 - 3 7.9 12.1 1.3 9.0 0.2 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF605 PF04652.11 AEO69176.1 - 0.72 9.1 17.8 0.99 8.7 12.4 1.2 1 0 0 1 1 1 0 Vta1 like SDA1 PF05285.7 AEO69176.1 - 7.4 5.7 8.8 16 4.6 6.1 1.5 1 0 0 1 1 1 0 SDA1 Ferric_reduct PF01794.14 AEO69177.1 - 1.7e-21 76.5 11.2 1.7e-21 76.5 7.8 2.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 AEO69177.1 - 3.3e-18 66.0 0.0 3e-10 40.2 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 AEO69177.1 - 1.8e-13 50.2 0.0 6.4e-13 48.4 0.0 1.9 1 1 0 1 1 1 1 FAD-binding domain Yippee-Mis18 PF03226.9 AEO69178.1 - 3.7e-24 84.5 0.2 4.3e-24 84.3 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.4 AEO69178.1 - 0.014 15.3 0.5 0.048 13.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) RIG-I_C-RD PF11648.3 AEO69178.1 - 0.027 14.3 1.2 0.055 13.3 0.8 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I Evr1_Alr PF04777.8 AEO69178.1 - 0.18 11.7 1.3 1.4 8.8 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family Nuc_sug_transp PF04142.10 AEO69179.1 - 1.7e-09 37.1 0.6 3.3e-09 36.2 0.2 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.6 AEO69179.1 - 5.2e-07 28.8 4.8 9.2e-07 28.0 3.3 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 AEO69179.1 - 8.9e-07 28.9 29.9 0.00039 20.4 4.0 3.8 3 1 1 4 4 4 3 EamA-like transporter family TPT PF03151.11 AEO69179.1 - 0.0097 15.5 18.6 0.31 10.6 5.6 3.1 3 1 0 3 3 3 2 Triose-phosphate Transporter family DUF2985 PF11204.3 AEO69180.1 - 3.7e-37 125.9 2.0 3.7e-37 125.9 1.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) DIM1 PF02966.11 AEO69181.1 - 8e-70 232.5 0.0 9e-70 232.3 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 AEO69181.1 - 0.055 13.5 0.2 0.089 12.9 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like Sen15 PF09631.5 AEO69182.1 - 9.4e-25 86.7 0.0 1.7e-24 85.9 0.0 1.4 1 1 0 1 1 1 1 Sen15 protein ADH_zinc_N PF00107.21 AEO69183.1 - 3.3e-17 62.2 0.0 4.8e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO69183.1 - 3.7e-05 23.4 0.2 6.3e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 AEO69183.1 - 0.046 14.2 0.0 0.075 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ADH_N PF08240.7 AEO69184.1 - 1.7e-18 66.3 0.5 2.2e-18 65.9 0.3 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 AEO69184.1 - 1.3e-07 31.1 0.4 2.3e-07 30.3 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated zf-C2H2 PF00096.21 AEO69185.1 - 1.7e-07 31.1 8.8 0.0055 16.9 1.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO69185.1 - 3.4e-07 30.1 10.2 0.00071 19.7 1.9 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO69185.1 - 0.00043 20.4 7.8 1.2 9.5 0.1 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-Di19 PF05605.7 AEO69185.1 - 1.9 8.6 7.8 0.38 10.9 0.6 2.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Peptidase_C2 PF00648.16 AEO69186.1 - 5.7e-30 104.3 0.0 9.1e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 AEO69186.1 - 6.2e-15 55.1 0.0 1.5e-06 27.8 0.0 3.2 3 0 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.13 AEO69186.1 - 0.11 12.4 2.2 0.21 11.4 1.5 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Mito_carr PF00153.22 AEO69187.1 - 4e-58 193.1 1.4 1.2e-20 73.0 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L29e PF01779.12 AEO69188.1 - 2.1e-23 81.8 8.6 3.3e-23 81.2 5.9 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family SAM_2 PF07647.12 AEO69189.1 - 3.9e-11 42.6 0.2 9.2e-11 41.4 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 AEO69189.1 - 5.4e-06 26.4 0.4 1.7e-05 24.8 0.2 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) IGR PF09597.5 AEO69189.1 - 0.025 14.4 0.4 0.068 13.0 0.2 1.7 1 0 0 1 1 1 0 IGR protein motif TPR_11 PF13414.1 AEO69190.1 - 1.6e-25 88.5 23.0 3.3e-08 33.0 0.0 8.4 8 0 0 8 8 8 5 TPR repeat TPR_12 PF13424.1 AEO69190.1 - 3e-13 49.4 22.8 0.0045 16.9 0.1 8.3 6 3 1 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 AEO69190.1 - 8.1e-13 47.3 14.5 0.0032 16.9 0.0 8.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 AEO69190.1 - 8.3e-13 47.1 23.9 0.038 13.9 0.0 11.2 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_8 PF13181.1 AEO69190.1 - 2.6e-11 42.4 5.8 0.81 9.6 0.0 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 AEO69190.1 - 2.7e-11 43.6 14.9 0.082 13.2 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 AEO69190.1 - 1.2e-08 35.3 54.1 1.4e-06 28.7 0.0 10.3 12 1 0 12 12 10 4 Tetratricopeptide repeat TPR_17 PF13431.1 AEO69190.1 - 0.0001 22.2 4.3 68 4.0 0.0 8.7 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.1 AEO69190.1 - 0.00049 19.7 24.5 1 9.3 0.1 8.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.1 AEO69190.1 - 0.0022 18.4 0.3 0.069 13.8 0.0 11.5 12 2 2 14 14 11 2 Tetratricopeptide repeat TPR_20 PF14561.1 AEO69190.1 - 0.0024 17.9 9.9 0.0067 16.5 0.0 4.8 5 1 1 6 6 5 1 Tetratricopeptide repeat Apc3 PF12895.2 AEO69190.1 - 0.0041 17.2 5.2 3.2 7.9 0.0 5.4 5 1 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 AEO69190.1 - 0.0043 17.4 12.7 4.1 8.0 0.1 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF1996 PF09362.5 AEO69191.1 - 6.2e-61 206.0 0.0 1.1e-60 205.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 AEO69191.1 - 1.2e-18 66.8 12.0 1.6e-18 66.3 6.4 2.4 2 0 0 2 2 2 1 WSC domain Nol1_Nop2_Fmu PF01189.12 AEO69192.1 - 2.1e-20 73.2 0.0 1.2e-15 57.6 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family EBP PF05241.7 AEO69193.1 - 9.4e-58 194.4 3.1 1.1e-57 194.1 2.1 1.0 1 0 0 1 1 1 1 Emopamil binding protein Cwf_Cwc_15 PF04889.7 AEO69194.1 - 4.8e-87 291.7 12.2 5.4e-87 291.5 8.4 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein GEMIN8 PF15348.1 AEO69194.1 - 0.19 11.7 5.3 0.25 11.3 3.7 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 OmpH PF03938.9 AEO69194.1 - 0.2 11.6 2.4 0.2 11.6 1.1 1.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SDA1 PF05285.7 AEO69194.1 - 0.34 10.1 21.6 0.45 9.7 15.0 1.2 1 0 0 1 1 1 0 SDA1 Glypican PF01153.14 AEO69194.1 - 0.47 9.0 5.0 0.52 8.8 3.5 1.1 1 0 0 1 1 1 0 Glypican Upf2 PF04050.9 AEO69194.1 - 4.4 7.0 18.6 8.5 6.1 12.9 1.5 1 0 0 1 1 1 0 Up-frameshift suppressor 2 CDC45 PF02724.9 AEO69194.1 - 4.8 5.0 20.1 6.6 4.6 13.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 AEO69194.1 - 6.8 6.6 16.4 7.4 6.5 10.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) TFIIF_alpha PF05793.7 AEO69194.1 - 8.8 4.5 24.2 12 4.1 16.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNase_PH PF01138.16 AEO69195.1 - 2.1e-22 79.8 0.0 3.5e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AEO69195.1 - 1.5e-07 31.2 0.0 2.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Arf PF00025.16 AEO69196.1 - 6.2e-40 136.2 0.0 8.9e-40 135.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 AEO69196.1 - 2.6e-15 55.9 0.0 1.5e-10 40.3 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 AEO69196.1 - 1.6e-09 37.2 0.0 1.9e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 AEO69196.1 - 1.7e-07 30.7 0.0 3.7e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 AEO69196.1 - 3.3e-07 29.7 0.0 7.4e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 AEO69196.1 - 3e-05 24.4 0.0 9.6e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 AEO69196.1 - 9.3e-05 21.9 0.0 0.00022 20.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AEO69196.1 - 0.0034 17.3 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AT_hook PF02178.14 AEO69197.1 - 0.045 13.4 16.3 0.69 9.7 2.2 2.7 2 0 0 2 2 2 0 AT hook motif DUF2834 PF11196.3 AEO69197.1 - 0.093 12.8 0.1 0.093 12.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2834) Adeno_terminal PF02459.10 AEO69197.1 - 4.4 5.3 6.0 6.2 4.8 4.2 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF77 PF01910.12 AEO69198.1 - 3.6e-32 109.8 1.8 4.2e-32 109.6 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Polysacc_deac_1 PF01522.16 AEO69198.1 - 0.0079 15.8 0.0 0.0093 15.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF1682 PF07946.9 AEO69199.1 - 3.7e-107 357.9 0.3 4.2e-107 357.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF2985 PF11204.3 AEO69199.1 - 0.08 12.7 0.1 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) DUF3635 PF12330.3 AEO69200.1 - 1.7e-06 28.0 0.0 1.7e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) Nucleoside_tran PF01733.13 AEO69201.1 - 5.9e-37 127.4 2.5 3.2e-24 85.6 0.0 2.5 2 0 0 2 2 2 2 Nucleoside transporter MFS_1 PF07690.11 AEO69201.1 - 5.8e-06 25.2 42.7 0.0051 15.5 5.9 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF1180 PF06679.7 AEO69201.1 - 0.75 9.6 2.5 1.2 9.0 1.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Ins_P5_2-kin PF06090.7 AEO69202.1 - 4.8e-15 55.4 0.0 5.6e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF2404 PF10296.4 AEO69203.1 - 0.00057 19.9 0.0 0.0018 18.3 0.0 1.8 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) YEATS PF03366.11 AEO69204.1 - 1.6e-29 101.4 0.2 2.5e-29 100.8 0.2 1.3 1 0 0 1 1 1 1 YEATS family Auts2 PF15336.1 AEO69204.1 - 0.033 14.2 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein NAD_binding_10 PF13460.1 AEO69205.1 - 8.7e-17 61.7 0.1 5.3e-15 55.9 0.1 2.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO69205.1 - 4.2e-07 29.6 0.0 1.3e-06 28.0 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO69205.1 - 2.7e-05 22.9 0.0 0.00015 20.5 0.0 2.0 2 1 1 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 AEO69205.1 - 0.0031 17.4 0.1 0.026 14.4 0.0 2.4 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_4 PF07993.7 AEO69205.1 - 0.0037 16.2 0.0 0.12 11.2 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 AEO69205.1 - 0.021 13.7 0.0 0.16 10.8 0.0 2.2 2 1 0 2 2 2 0 RmlD substrate binding domain SYF2 PF08231.7 AEO69206.1 - 1.1e-51 174.9 10.2 1.1e-51 174.9 7.0 1.7 2 0 0 2 2 2 1 SYF2 splicing factor DUF3729 PF12526.3 AEO69206.1 - 0.32 12.3 10.0 0.82 11.0 6.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) ARD PF03079.9 AEO69206.1 - 3.2 7.6 7.1 0.58 10.0 0.1 2.5 1 1 1 2 2 2 0 ARD/ARD' family DUF1179 PF06678.6 AEO69206.1 - 6.9 7.0 6.7 7.3 6.9 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1179) HEAT PF02985.17 AEO69207.1 - 5.4e-05 22.9 2.6 0.067 13.3 0.3 4.7 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 AEO69207.1 - 0.82 10.2 10.7 0.2 12.2 0.9 5.0 6 0 0 6 6 6 0 HEAT-like repeat AA_permease PF00324.16 AEO69209.1 - 1e-27 96.6 10.5 8.1e-25 87.1 7.3 2.0 1 1 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 AEO69210.1 - 3.9e-38 131.0 0.0 6.2e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO69210.1 - 6.5e-27 94.2 0.0 9.1e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO69210.1 - 0.073 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AEO69210.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF1749 PF08538.5 AEO69211.1 - 4.8e-83 278.5 0.0 6.7e-83 278.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 AEO69211.1 - 2.3e-13 50.5 2.0 3.5e-13 49.9 1.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO69211.1 - 6.4e-06 25.9 0.0 1.2e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO69211.1 - 0.047 13.2 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold p450 PF00067.17 AEO69214.1 - 2e-43 148.5 0.0 2.4e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF-5_eIF-2B PF01873.12 AEO69215.1 - 6.9e-40 135.5 0.0 1.3e-39 134.7 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 AEO69215.1 - 6.2e-27 93.3 0.5 1.7e-26 91.9 0.4 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Zn-ribbon_8 PF09723.5 AEO69215.1 - 0.21 11.5 1.2 0.52 10.3 0.8 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Herpes_LMP1 PF05297.6 AEO69216.1 - 1.1 8.0 17.6 1.2 7.9 12.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF605 PF04652.11 AEO69216.1 - 2.9 7.1 14.7 3.2 7.0 10.2 1.1 1 0 0 1 1 1 0 Vta1 like CoaE PF01121.15 AEO69217.1 - 1e-42 145.5 0.1 1.2e-41 142.1 0.0 2.0 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.1 AEO69217.1 - 8.1e-05 22.5 0.1 0.0011 18.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO69217.1 - 0.00029 21.6 0.5 0.0018 19.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AEO69217.1 - 0.0059 16.9 0.3 0.41 10.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain CcmH PF03918.9 AEO69217.1 - 0.064 12.2 0.8 0.11 11.5 0.5 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein FixP_N PF14715.1 AEO69217.1 - 0.15 11.5 2.5 0.25 10.7 1.7 1.3 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF4320 PF14208.1 AEO69219.1 - 0.08 12.8 0.0 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) Tim17 PF02466.14 AEO69220.1 - 8e-27 93.8 5.0 1.1e-26 93.4 3.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2428 PF10350.4 AEO69221.1 - 7.4e-69 231.6 0.0 5.8e-68 228.6 0.0 2.4 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 AEO69221.1 - 1.4e-10 40.3 18.6 0.077 13.1 0.0 8.5 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.1 AEO69221.1 - 3e-05 24.2 12.1 0.0056 16.9 0.2 6.0 6 0 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 AEO69221.1 - 6.3e-05 23.3 12.8 0.0061 17.0 0.3 6.0 5 0 0 5 5 5 2 HEAT-like repeat Arm PF00514.18 AEO69221.1 - 1.6 8.6 5.9 22 5.0 0.1 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF4231 PF14015.1 AEO69224.1 - 0.055 13.4 0.6 0.25 11.3 0.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Gtr1_RagA PF04670.7 AEO69226.1 - 3.4e-72 242.3 0.1 4.2e-72 242.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AEO69226.1 - 0.0004 20.8 0.0 0.0029 18.0 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AEO69226.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family MIF PF01187.13 AEO69227.1 - 4.6e-09 36.3 0.0 7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Sulfate_tra_GLY PF13792.1 AEO69228.1 - 0.06 13.0 3.5 0.22 11.2 0.0 2.9 3 0 0 3 3 3 0 Sulfate transporter N-terminal domain with GLY motif STAG PF08514.6 AEO69228.1 - 0.09 12.4 1.6 0.14 11.8 0.3 1.8 2 0 0 2 2 2 0 STAG domain Abhydrolase_6 PF12697.2 AEO69229.1 - 5.8e-05 23.0 0.9 5.8e-05 23.0 0.6 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.10 AEO69229.1 - 0.019 13.9 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 AEO69229.1 - 0.072 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) GST_N PF02798.15 AEO69230.1 - 1.7e-09 37.6 0.0 3.8e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 AEO69230.1 - 3.4e-08 33.5 0.0 6.5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO69230.1 - 7.7e-07 29.0 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 AEO69230.1 - 0.00013 21.9 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 AEO69230.1 - 0.00038 20.2 0.0 0.00061 19.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AEO69230.1 - 0.0095 16.3 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SAP18 PF06487.7 AEO69232.1 - 1e-34 118.9 0.0 1.3e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) DUF1039 PF06287.6 AEO69232.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1039) Prp18 PF02840.10 AEO69233.1 - 4.9e-51 172.3 1.0 5.3e-51 172.2 0.0 1.5 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 AEO69233.1 - 5.9e-12 44.6 0.2 5.9e-12 44.6 0.1 2.8 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like CAF-1_p150 PF11600.3 AEO69233.1 - 0.1 11.9 22.3 0.19 11.0 15.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MIP-T3 PF10243.4 AEO69233.1 - 0.13 10.7 12.9 0.18 10.2 8.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 AEO69233.1 - 0.24 9.2 10.0 0.31 8.9 6.9 1.1 1 0 0 1 1 1 0 Nop14-like family Borrelia_P83 PF05262.6 AEO69233.1 - 1.4 7.1 8.8 1.8 6.7 6.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Milton PF12448.3 AEO69233.1 - 6.8 6.8 15.1 2.2 8.4 6.7 2.5 1 1 1 2 2 2 0 Kinesin associated protein RPN7 PF10602.4 AEO69234.1 - 9.6e-50 168.3 0.3 1.8e-49 167.5 0.2 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 AEO69234.1 - 3.1e-14 53.1 0.0 2.2e-13 50.4 0.0 2.3 2 0 0 2 2 2 1 PCI domain KNOX1 PF03790.8 AEO69234.1 - 0.094 12.0 0.1 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 KNOX1 domain FeoC PF09012.5 AEO69234.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 FeoC like transcriptional regulator Fungal_trans PF04082.13 AEO69235.1 - 6.1e-20 71.1 0.0 1.1e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_M24 PF00557.19 AEO69236.1 - 5.7e-61 205.7 0.1 8e-61 205.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 AEO69236.1 - 6.7e-23 80.5 0.0 1.5e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Lectin_leg-like PF03388.8 AEO69237.1 - 3.3e-26 91.8 0.0 5.8e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Legume-like lectin family DUF3708 PF12501.3 AEO69237.1 - 0.0047 16.7 0.7 0.0047 16.7 0.5 2.0 1 1 1 2 2 2 1 Phosphate ATP-binding cassette transporter DUF2408 PF10303.4 AEO69237.1 - 1.5 8.9 6.0 0.1 12.7 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Alg6_Alg8 PF03155.10 AEO69238.1 - 3.7e-145 484.3 28.2 4.8e-145 483.9 19.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.4 AEO69239.1 - 2.3e-39 133.6 1.5 2.8e-39 133.3 0.0 2.0 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 AEO69239.1 - 1.2e-16 60.2 0.2 1.9e-16 59.5 0.2 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 AEO69239.1 - 3.7e-14 51.9 0.5 7.7e-14 50.9 0.3 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 AEO69239.1 - 0.00021 21.0 0.0 0.00067 19.4 0.0 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 AEO69239.1 - 0.013 15.2 0.0 0.037 13.7 0.0 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 3 DUF87 PF01935.12 AEO69239.1 - 0.34 10.6 1.8 0.78 9.5 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF4201 PF13870.1 AEO69239.1 - 1.8 7.9 15.9 2.7 7.4 6.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Nop53 PF07767.6 AEO69239.1 - 5 5.9 29.6 3 6.7 5.9 2.6 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Thioredoxin_6 PF13848.1 AEO69240.1 - 3.4e-08 33.5 0.0 3.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Zn_clus PF00172.13 AEO69241.1 - 0.013 15.3 7.0 0.028 14.3 4.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain P_C PF06640.6 AEO69242.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 P protein C-terminus Kelch_5 PF13854.1 AEO69243.1 - 5.3e-09 35.8 15.6 4.2e-08 32.9 0.4 5.8 6 0 0 6 6 6 1 Kelch motif Kelch_4 PF13418.1 AEO69243.1 - 4.5e-08 32.7 14.2 0.33 10.7 0.1 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.1 AEO69243.1 - 3.6e-05 23.7 20.9 0.17 12.1 0.2 5.8 5 1 1 6 6 6 3 Kelch motif Kelch_2 PF07646.10 AEO69243.1 - 0.011 15.4 9.7 0.82 9.5 0.0 4.5 5 0 0 5 5 5 0 Kelch motif Kelch_3 PF13415.1 AEO69243.1 - 0.028 14.5 9.8 1.8 8.8 0.4 4.8 4 0 0 4 4 4 0 Galactose oxidase, central domain tRNA_int_end_N2 PF12928.2 AEO69243.1 - 0.12 11.8 0.0 2.7 7.4 0.0 2.4 2 1 0 2 2 2 0 tRNA-splicing endonuclease subunit sen54 N-term Kelch_1 PF01344.20 AEO69243.1 - 9 5.9 16.5 28 4.3 0.1 5.4 6 0 0 6 6 6 0 Kelch motif Ecl1 PF12855.2 AEO69244.1 - 1.3e-11 43.5 2.3 2.2e-11 42.8 1.6 1.3 1 0 0 1 1 1 1 Life-span regulatory factor DUF581 PF04570.9 AEO69244.1 - 1.6e-05 24.0 1.1 2.8e-05 23.3 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF581) DUF329 PF03884.9 AEO69244.1 - 0.012 15.1 0.9 0.012 15.1 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF329) C1_1 PF00130.17 AEO69244.1 - 0.31 10.7 2.2 0.53 10.0 1.5 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) E1-E2_ATPase PF00122.15 AEO69245.1 - 3.9e-22 78.4 0.0 7.5e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 AEO69245.1 - 3.6e-21 76.2 0.0 9.1e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AEO69245.1 - 9.2e-17 62.1 3.2 1.1e-15 58.5 2.2 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO69245.1 - 1.1e-11 44.4 0.0 3.6e-11 42.8 0.0 1.9 1 1 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AEO69245.1 - 0.0012 18.4 0.4 0.013 15.0 0.1 2.1 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AEO69245.1 - 0.024 14.8 0.0 0.08 13.1 0.0 1.9 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Cript PF10235.4 AEO69246.1 - 6.2e-32 109.8 9.4 9.4e-32 109.2 6.5 1.3 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT DZR PF12773.2 AEO69246.1 - 0.0044 16.8 8.1 0.0044 16.8 5.6 2.4 2 1 0 2 2 2 1 Double zinc ribbon DUF2039 PF10217.4 AEO69246.1 - 0.17 11.9 13.6 0.031 14.3 4.8 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-ribbon_3 PF13248.1 AEO69246.1 - 0.33 10.2 10.3 0.33 10.2 1.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_5 PF14634.1 AEO69246.1 - 0.51 10.1 11.1 0.18 11.5 2.9 2.8 3 0 0 3 3 3 0 zinc-RING finger domain Ribosomal_L32p PF01783.18 AEO69246.1 - 2 8.6 13.8 0.96 9.6 2.5 3.1 2 1 1 3 3 3 0 Ribosomal L32p protein family zf-C3HC4_3 PF13920.1 AEO69246.1 - 3 7.6 14.0 0.32 10.7 2.7 2.9 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-FPG_IleRS PF06827.9 AEO69246.1 - 8.9 6.0 11.2 2.2 8.0 1.5 3.2 3 1 0 3 3 3 0 Zinc finger found in FPG and IleRS Abhydrolase_6 PF12697.2 AEO69247.1 - 2.4e-36 125.7 0.9 3.4e-36 125.2 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO69247.1 - 4.4e-16 59.1 0.0 4.7e-15 55.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO69247.1 - 7.6e-11 41.9 0.0 1.8e-10 40.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AEO69247.1 - 1.5e-06 27.9 0.0 2.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 AEO69247.1 - 0.0079 15.7 0.0 0.015 14.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 AEO69247.1 - 0.023 14.5 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Pinin_SDK_memA PF04696.8 AEO69248.1 - 1e-08 34.8 30.3 4.8e-08 32.6 12.2 3.1 2 1 1 3 3 3 2 pinin/SDK/memA/ protein conserved region PHF5 PF03660.9 AEO69249.1 - 1.6e-51 172.8 10.6 1.8e-51 172.6 7.3 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 AEO69249.1 - 0.97 9.2 15.7 17 5.3 10.0 2.8 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.1 AEO69249.1 - 1.4 8.7 15.7 2.9 7.6 0.5 3.0 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 AEO69249.1 - 4.5 4.8 5.8 4.5 4.8 4.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PHD PF00628.24 AEO69249.1 - 8.1 6.2 15.6 0.22 11.2 4.5 2.5 1 1 1 2 2 2 0 PHD-finger DUF1451 PF07295.6 AEO69250.1 - 0.93 9.2 4.8 1.7 8.4 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Caldesmon PF02029.10 AEO69250.1 - 8 4.7 19.9 15 3.8 13.8 1.3 1 0 0 1 1 1 0 Caldesmon BP28CT PF08146.7 AEO69251.1 - 4e-44 150.0 1.2 9.7e-44 148.7 0.0 2.3 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 AEO69251.1 - 2.5e-24 85.5 0.6 2.5e-24 85.5 0.4 6.3 6 0 0 6 6 6 2 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 AEO69251.1 - 7.5e-05 22.4 10.2 0.051 13.6 0.1 6.6 6 0 0 6 6 6 2 HEAT repeat NOC3p PF07540.6 AEO69252.1 - 1.4e-31 108.5 0.0 5.2e-31 106.7 0.0 2.0 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 AEO69252.1 - 3.9e-30 104.4 0.0 9.5e-30 103.2 0.0 1.7 1 0 0 1 1 1 1 CBF/Mak21 family DUF2201_N PF13203.1 AEO69252.1 - 1.8 7.6 11.0 0.79 8.8 4.1 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain STE PF02200.11 AEO69254.1 - 4.2e-62 207.1 0.2 6.8e-62 206.4 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 AEO69254.1 - 2.3e-12 46.4 11.8 1.4e-06 28.2 1.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO69254.1 - 1.2e-10 40.9 8.9 3.9e-05 23.6 0.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO69254.1 - 2.9e-09 36.7 4.5 2.9e-09 36.7 3.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AEO69254.1 - 0.00011 22.1 3.8 0.0047 17.0 0.1 3.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AEO69254.1 - 0.00025 20.8 4.0 0.00025 20.8 0.1 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-RING_3 PF14369.1 AEO69254.1 - 0.0056 16.6 0.1 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 zinc-finger zf-Di19 PF05605.7 AEO69254.1 - 0.045 13.8 0.2 0.045 13.8 0.2 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FYDLN_acid PF09538.5 AEO69254.1 - 0.046 14.2 0.1 0.11 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-TRAF PF02176.13 AEO69254.1 - 0.052 13.9 2.5 0.09 13.1 1.7 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2HC_2 PF13913.1 AEO69254.1 - 0.11 12.1 3.3 2.1 8.1 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.2 AEO69254.1 - 6.1 7.1 6.6 5.5 7.3 0.3 3.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF4602 PF15375.1 AEO69255.1 - 3.6e-06 27.0 8.7 3.6e-06 27.0 6.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4602) His_biosynth PF00977.16 AEO69256.1 - 1.6e-33 115.8 0.0 2e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 AEO69256.1 - 0.054 12.6 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.12 AEO69256.1 - 0.15 11.1 0.2 1.5 7.9 0.1 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI Anillin PF08174.6 AEO69257.1 - 3e-36 124.5 0.1 1.8e-34 118.7 0.0 3.0 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.24 AEO69257.1 - 5.1e-07 29.8 0.0 1.6e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 PH domain Pyr_redox_2 PF07992.9 AEO69258.1 - 1.2e-35 123.2 0.0 7.4e-35 120.6 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO69258.1 - 1e-11 45.0 0.0 3.4e-09 36.9 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO69258.1 - 0.0004 20.5 0.0 0.032 14.2 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO69258.1 - 0.06 13.3 0.0 16 5.5 0.0 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain CAP_N PF01213.14 AEO69258.1 - 0.1 11.8 1.6 4.5 6.4 0.1 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal RNase_P_pop3 PF08228.6 AEO69259.1 - 8.6e-08 32.1 0.0 1.2e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 RNase P subunit Pop3 UCH PF00443.24 AEO69260.1 - 1.6e-42 145.4 1.9 4.5e-42 144.0 1.2 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 AEO69260.1 - 1.4e-27 96.1 0.0 2.8e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH_1 PF13423.1 AEO69260.1 - 1.5e-19 70.5 1.0 3.2e-19 69.4 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PRCC PF10253.4 AEO69262.1 - 4.2e-31 109.0 10.1 4.2e-31 109.0 7.0 3.3 2 2 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting SIN1 PF05422.7 AEO69263.1 - 1.4e-42 145.9 0.0 1.3e-21 76.7 0.0 3.2 3 0 0 3 3 3 3 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 AEO69263.1 - 0.02 14.7 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Bindin PF02084.10 AEO69263.1 - 0.079 12.9 1.6 0.76 9.7 0.1 2.2 2 0 0 2 2 2 0 Bindin Baculo_PEP_C PF04513.7 AEO69264.1 - 0.024 14.4 0.6 0.037 13.8 0.4 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ACT_6 PF13740.1 AEO69264.1 - 0.072 12.8 2.4 0.34 10.6 0.1 2.7 2 1 1 3 3 3 0 ACT domain DUF883 PF05957.8 AEO69264.1 - 0.096 13.0 0.9 0.19 12.1 0.6 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) SseC PF04888.7 AEO69264.1 - 1.9 7.7 25.6 2.7 7.2 17.7 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family BRF1 PF07741.8 AEO69265.1 - 0.44 10.8 5.9 0.23 11.7 2.0 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain bZIP_1 PF00170.16 AEO69266.1 - 6.8e-06 25.9 21.6 7.1e-06 25.8 14.1 1.7 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 AEO69266.1 - 0.0001 22.0 24.7 0.00018 21.2 15.9 2.1 1 1 1 2 2 2 1 Basic region leucine zipper CENP-H PF05837.7 AEO69266.1 - 0.11 12.6 5.2 0.19 11.8 3.6 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) V_ATPase_I PF01496.14 AEO69266.1 - 0.14 10.0 4.2 0.19 9.5 2.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HlyD PF00529.15 AEO69266.1 - 0.17 11.1 5.2 0.31 10.3 3.6 1.4 1 0 0 1 1 1 0 HlyD family secretion protein GAS PF13851.1 AEO69266.1 - 0.19 10.8 8.8 0.28 10.3 6.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 AEO69266.1 - 0.68 9.5 10.5 1.2 8.7 7.3 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 AEO69266.1 - 1 8.3 9.8 1.5 7.7 6.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 AEO69266.1 - 5 6.6 9.0 5.5 6.5 5.5 1.5 1 1 0 1 1 1 0 Septum formation initiator Mnd1 PF03962.10 AEO69266.1 - 8.4 6.0 9.7 12 5.4 6.7 1.1 1 0 0 1 1 1 0 Mnd1 family SGL PF08450.7 AEO69268.1 - 4.8e-67 225.9 0.0 5.6e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 AEO69268.1 - 0.017 15.0 1.0 1.1 9.4 0.0 3.0 2 0 0 2 2 2 0 Two component regulator propeller PD40 PF07676.7 AEO69268.1 - 0.05 13.2 0.0 0.17 11.5 0.0 1.9 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Lactonase PF10282.4 AEO69268.1 - 0.08 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller WD40 PF00400.27 AEO69269.1 - 2.6e-71 233.1 22.6 1.5e-12 46.8 0.2 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 AEO69269.1 - 4e-06 25.2 3.8 0.00071 17.8 0.3 4.1 3 2 2 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AEO69269.1 - 0.0013 17.5 0.4 0.56 8.8 0.1 2.7 1 1 0 3 3 3 2 Nup133 N terminal like XkdW PF09636.5 AEO69269.1 - 0.048 13.5 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 XkdW protein DctQ PF04290.7 AEO69270.1 - 0.15 11.8 0.4 0.26 11.0 0.3 1.3 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component LMBR1 PF04791.11 AEO69271.1 - 5.9e-32 110.8 2.1 7.9e-32 110.4 1.5 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Aldedh PF00171.17 AEO69272.1 - 1.7e-185 616.8 0.7 1.9e-185 616.6 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 AEO69272.1 - 0.00032 19.9 0.1 0.16 11.1 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1487) Chitin_bind_1 PF00187.14 AEO69274.1 - 0.00011 22.1 20.7 0.0002 21.2 14.4 1.4 1 0 0 1 1 1 1 Chitin recognition protein Polysacc_deac_1 PF01522.16 AEO69275.1 - 1.2e-14 54.0 0.1 2.2e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 AEO69275.1 - 3e-05 23.8 20.5 3e-05 23.8 14.2 3.2 3 0 0 3 3 3 1 Chitin recognition protein DUF3800 PF12686.2 AEO69276.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) DUF3287 PF11690.3 AEO69276.1 - 0.25 11.4 2.7 0.6 10.2 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) TOH_N PF12549.3 AEO69277.1 - 4.6 6.9 6.3 0.48 10.0 0.3 2.5 3 0 0 3 3 3 0 Tyrosine hydroxylase N terminal Glyco_hydro_12 PF01670.11 AEO69278.1 - 0.071 12.8 0.0 0.076 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 12 Peptidase_C12 PF01088.16 AEO69279.1 - 9.5e-14 51.0 0.0 3.2e-08 33.0 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF3336 PF11815.3 AEO69282.1 - 5.4e-56 188.1 3.6 8.7e-56 187.4 2.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 AEO69282.1 - 9.8e-21 74.6 0.0 2.7e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase Arf PF00025.16 AEO69283.1 - 8.3e-67 223.7 0.0 9.3e-67 223.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 AEO69283.1 - 1.6e-10 40.2 0.1 7e-07 28.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 AEO69283.1 - 7.9e-08 31.8 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 AEO69283.1 - 8.6e-08 31.6 0.0 1.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 AEO69283.1 - 1.1e-07 32.3 0.0 1.5e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AEO69283.1 - 2e-07 30.9 0.0 2.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 AEO69283.1 - 9.8e-06 24.8 0.0 1.1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AEO69283.1 - 7e-05 22.3 0.0 0.0027 17.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.14 AEO69283.1 - 0.075 12.4 0.0 5.4 6.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 AEO69283.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF2457 PF10446.4 AEO69284.1 - 5e-150 500.2 42.9 5e-150 500.2 29.7 2.9 2 2 0 2 2 2 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 AEO69284.1 - 0.66 7.8 29.0 1 7.1 20.1 1.3 1 0 0 1 1 1 0 Nop14-like family GCD14_N PF14801.1 AEO69285.1 - 0.3 10.6 1.8 0.31 10.6 0.4 1.6 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term ATP-synt_DE_N PF02823.11 AEO69286.1 - 6.1e-19 67.5 0.0 9.1e-19 67.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Steroid_dh PF02544.11 AEO69287.1 - 2.1e-12 47.0 0.4 4.2e-12 46.0 0.3 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase 2OG-FeII_Oxy_2 PF13532.1 AEO69288.1 - 6.1e-15 55.5 0.0 1.6e-13 50.9 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 AEO69288.1 - 2.9e-05 24.2 0.0 0.00021 21.5 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TGS PF02824.16 AEO69290.1 - 5.2e-23 80.6 0.1 9.8e-23 79.7 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 AEO69290.1 - 9e-18 64.3 0.0 2.8e-17 62.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO69290.1 - 7.5e-09 35.0 0.0 4e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 AEO69290.1 - 2e-05 24.1 0.1 0.28 10.5 0.0 3.6 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 AEO69290.1 - 0.00017 21.4 0.0 0.038 13.8 0.0 2.4 2 0 0 2 2 2 2 Dynamin family ArgK PF03308.11 AEO69290.1 - 0.0068 15.2 0.2 0.024 13.4 0.1 1.9 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 AEO69290.1 - 0.03 14.8 0.0 0.37 11.2 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein DUF211 PF02680.9 AEO69290.1 - 0.1 12.4 0.5 0.34 10.7 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 AAA_28 PF13521.1 AEO69290.1 - 0.15 11.9 0.0 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain HTH_Tnp_Tc5 PF03221.11 AEO69292.1 - 2.2e-10 40.1 0.0 7.3e-10 38.5 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 AEO69292.1 - 6.5e-07 28.6 0.0 1.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.17 AEO69292.1 - 0.0037 16.9 0.0 0.044 13.4 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_Tnp_4 PF13613.1 AEO69292.1 - 0.022 14.2 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR_2 PF12802.2 AEO69292.1 - 0.06 13.0 0.1 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 MarR family HTH_38 PF13936.1 AEO69292.1 - 0.14 11.7 0.0 0.4 10.2 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 AEO69292.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 PXA PF02194.10 AEO69294.1 - 6.2e-42 143.2 0.1 1e-41 142.5 0.1 1.3 1 0 0 1 1 1 1 PXA domain zf-Mss51 PF13824.1 AEO69295.1 - 3.9e-27 93.8 8.4 9e-27 92.7 5.8 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 AEO69295.1 - 0.016 15.0 3.5 0.016 15.0 2.4 2.0 2 0 0 2 2 2 0 MYND finger CPSF_A PF03178.10 AEO69296.1 - 1.4e-99 333.2 0.0 4.5e-99 331.5 0.0 1.9 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 AEO69296.1 - 3.3e-65 220.1 0.0 5e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF1945 PF09178.5 AEO69296.1 - 0.012 15.4 0.1 0.072 12.9 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1945) WD40 PF00400.27 AEO69296.1 - 0.14 12.0 0.1 0.55 10.2 0.1 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat UBA_4 PF14555.1 AEO69297.1 - 0.023 14.2 0.1 0.038 13.5 0.1 1.3 1 0 0 1 1 1 0 UBA-like domain Pex14_N PF04695.8 AEO69297.1 - 4.7 7.2 7.6 7.3 6.6 0.1 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lipase_GDSL_2 PF13472.1 AEO69298.1 - 8.2e-19 68.4 0.0 1.1e-18 68.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO69298.1 - 6.3e-14 52.3 0.0 7.6e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Isochorismatase PF00857.15 AEO69301.1 - 6.6e-28 97.8 0.1 9.9e-28 97.2 0.1 1.3 1 0 0 1 1 1 1 Isochorismatase family Glyco_transf_4 PF13439.1 AEO69301.1 - 0.11 12.1 0.2 0.5 10.0 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase Family 4 HK PF02110.10 AEO69302.1 - 1.4e-77 260.1 0.7 2.2e-77 259.5 0.5 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 AEO69302.1 - 9.8e-60 200.7 0.5 1.7e-59 199.9 0.3 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 AEO69302.1 - 0.00016 20.9 0.1 0.00031 20.0 0.1 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.12 AEO69302.1 - 0.0013 18.0 0.3 0.0026 17.0 0.2 1.5 1 0 0 1 1 1 1 Carbohydrate kinase Lyase_1 PF00206.15 AEO69303.1 - 2.2e-25 89.5 0.2 3.1e-25 89.0 0.2 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 AEO69303.1 - 2.7e-15 56.1 0.0 8e-15 54.6 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF2360 PF10152.4 AEO69304.1 - 3.2 8.0 8.1 17 5.6 0.0 2.9 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) CHIPS PF11434.3 AEO69305.1 - 0.2 11.3 3.6 0.24 11.0 2.5 1.2 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS Aminotran_1_2 PF00155.16 AEO69306.1 - 4.8e-89 298.8 0.0 6.9e-89 298.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 AEO69306.1 - 5.8e-07 28.5 0.0 1.5e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 AEO69306.1 - 3.6e-06 25.5 0.0 6.1e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 AEO69306.1 - 0.0095 15.0 0.2 0.027 13.5 0.1 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SNF2_N PF00176.18 AEO69307.1 - 8e-48 162.7 0.1 1.3e-47 162.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO69307.1 - 2.6e-12 46.4 0.3 6.5e-12 45.1 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO69307.1 - 0.00098 18.9 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Arch_fla_DE PF04659.8 AEO69307.1 - 0.1 12.4 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Archaeal flagella protein HDA2-3 PF11496.3 AEO69307.1 - 0.11 11.2 0.2 0.33 9.7 0.0 1.7 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 GSH_synth_ATP PF03917.12 AEO69308.1 - 1.9e-70 237.3 0.0 4.5e-70 236.0 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 AEO69308.1 - 6.7e-31 106.4 0.0 1e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Sec1 PF00995.18 AEO69309.1 - 1.5e-152 509.1 0.0 1.7e-152 508.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF2404 PF10296.4 AEO69310.1 - 1.5e-07 31.4 0.0 2.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) MBOAT PF03062.14 AEO69311.1 - 2.7e-53 181.1 2.7 4.8e-53 180.3 1.9 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Abi PF02517.11 AEO69313.1 - 2.2e-13 50.1 4.9 2.2e-13 50.1 3.4 2.6 3 1 0 3 3 3 1 CAAX protease self-immunity TPT PF03151.11 AEO69314.1 - 1.4e-11 44.2 3.6 1.4e-11 44.2 2.5 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 AEO69314.1 - 3e-09 36.2 9.9 3.6e-09 35.9 6.9 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 AEO69314.1 - 2.2e-05 24.4 17.2 0.00019 21.4 2.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family PHO4 PF01384.15 AEO69314.1 - 0.0071 15.0 6.4 0.014 14.0 4.5 1.6 1 1 0 1 1 1 1 Phosphate transporter family Multi_Drug_Res PF00893.14 AEO69314.1 - 1.1 9.8 7.3 5.8 7.4 0.4 2.7 2 0 0 2 2 2 0 Small Multidrug Resistance protein PRA1 PF03208.14 AEO69314.1 - 5.6 6.2 10.2 0.38 10.0 0.1 3.0 1 1 1 3 3 3 0 PRA1 family protein adh_short PF00106.20 AEO69316.1 - 2.1e-19 70.0 0.0 3.2e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO69316.1 - 5.5e-11 42.4 0.0 9.2e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO69316.1 - 5.5e-08 32.5 0.0 9.4e-08 31.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO69316.1 - 0.00028 19.7 0.0 0.00041 19.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 AEO69316.1 - 0.00079 19.4 0.0 0.0016 18.4 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 AEO69316.1 - 0.01 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 AEO69316.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 AEO69316.1 - 0.065 12.4 0.1 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family SAPS PF04499.10 AEO69316.1 - 0.15 10.6 0.7 0.21 10.1 0.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CD99L2 PF12301.3 AEO69316.1 - 0.19 11.4 12.5 0.32 10.6 8.7 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 MIP-T3 PF10243.4 AEO69316.1 - 1.4 7.2 19.9 1.9 6.8 13.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2201_N PF13203.1 AEO69316.1 - 1.5 7.8 5.9 2.1 7.4 4.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Pox_Ag35 PF03286.9 AEO69316.1 - 4.9 6.6 14.2 8.3 5.8 9.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF1510 PF07423.6 AEO69316.1 - 6.8 5.9 19.4 9.7 5.4 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ARD PF03079.9 AEO69317.1 - 2.6e-44 150.9 0.0 3e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 AEO69317.1 - 2.3e-09 36.6 0.1 3.9e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 AEO69317.1 - 7.3e-07 28.9 0.0 9.5e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 AEO69317.1 - 0.0031 16.9 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Cupin DER1 PF04511.10 AEO69318.1 - 3e-53 180.2 3.6 3.4e-53 180.0 2.5 1.0 1 0 0 1 1 1 1 Der1-like family Histone PF00125.19 AEO69320.1 - 1.1e-28 99.0 0.7 1.9e-28 98.4 0.5 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 AEO69320.1 - 0.00027 21.0 0.0 0.00043 20.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AEO69320.1 - 0.039 14.0 0.1 0.083 12.9 0.1 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PBD PF00786.23 AEO69321.1 - 0.011 16.1 0.7 0.033 14.6 0.1 2.3 2 0 0 2 2 2 0 P21-Rho-binding domain RabGAP-TBC PF00566.13 AEO69324.1 - 3.8e-26 91.9 0.0 5.8e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain His_Phos_1 PF00300.17 AEO69326.1 - 1.3e-24 87.0 0.0 3.2e-24 85.8 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF1762 PF08574.5 AEO69328.1 - 5.4e-09 36.3 12.1 5.4e-09 36.3 8.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) Iso_dh PF00180.15 AEO69331.1 - 6.5e-130 433.1 0.0 7.6e-130 432.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PHD PF00628.24 AEO69332.1 - 2.2e-07 30.4 4.1 3.5e-07 29.8 2.8 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 AEO69332.1 - 0.025 13.8 1.8 0.042 13.1 1.3 1.4 1 0 0 1 1 1 0 PHD-finger DUF4451 PF14616.1 AEO69333.1 - 5.6e-35 119.8 0.4 1e-34 118.9 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) DUF605 PF04652.11 AEO69336.1 - 1.4 8.2 13.0 1.4 8.2 9.0 1.1 1 0 0 1 1 1 0 Vta1 like Actin PF00022.14 AEO69337.1 - 1.6e-27 95.9 0.0 4.9e-18 64.7 0.0 2.4 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 AEO69337.1 - 0.017 13.6 0.0 0.55 8.7 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein PI-PLC-X PF00388.14 AEO69339.1 - 7.5e-62 207.0 0.0 1.2e-61 206.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 AEO69339.1 - 7.6e-39 132.3 0.0 1.4e-38 131.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EspB PF05802.6 AEO69339.1 - 0.041 12.8 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein DUF2040 PF09745.4 AEO69340.1 - 9.4e-34 115.9 11.1 9.4e-34 115.9 7.7 3.5 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) zf-Tim10_DDP PF02953.10 AEO69341.1 - 2.7e-22 77.8 1.3 3.3e-22 77.5 0.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.3 AEO69341.1 - 0.0045 16.7 0.1 0.0066 16.2 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3398) Lectin_leg-like PF03388.8 AEO69342.1 - 7.6e-68 228.0 0.0 9.2e-68 227.8 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 AEO69342.1 - 0.00084 18.7 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain Pkinase PF00069.20 AEO69343.1 - 1.9e-71 240.2 0.1 4.1e-71 239.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO69343.1 - 1e-37 129.6 0.3 3.1e-37 128.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO69343.1 - 2.7e-08 33.1 0.2 4.6e-08 32.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AEO69343.1 - 0.048 13.3 4.3 0.19 11.4 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2252 PF10009.4 AEO69343.1 - 0.68 8.7 6.3 0.052 12.4 0.8 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) PAT1 PF09770.4 AEO69343.1 - 4.4 5.4 51.9 5.8 5.0 36.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CorA PF01544.13 AEO69344.1 - 2.2e-05 23.6 2.2 4.1e-05 22.7 0.1 2.2 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein EB1 PF03271.12 AEO69344.1 - 0.027 14.5 0.1 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 EB1-like C-terminal motif DUF2029 PF09594.5 AEO69344.1 - 0.028 13.9 0.1 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) DUF4381 PF14316.1 AEO69344.1 - 0.21 11.6 3.3 0.72 9.9 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DEAD PF00270.24 AEO69345.1 - 1.9e-32 112.0 0.0 3.5e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO69345.1 - 9e-18 63.9 0.0 1.8e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AEO69345.1 - 0.00013 20.9 0.0 0.00019 20.3 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 AEO69345.1 - 0.00064 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Aa_trans PF01490.13 AEO69346.1 - 1.7e-27 95.9 12.9 2.3e-27 95.5 9.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.13 AEO69347.1 - 1.2e-11 43.7 0.0 1.3e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase PF00069.20 AEO69349.1 - 4.6e-61 206.2 0.0 7.9e-61 205.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO69349.1 - 3.4e-33 114.8 0.0 5e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO69349.1 - 1.4e-12 47.1 0.0 1.7e-09 37.1 0.0 3.0 2 1 1 3 3 3 2 Kinase-like HAD_2 PF13419.1 AEO69350.1 - 8.1e-31 107.5 0.0 9.6e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO69350.1 - 0.00077 19.1 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF3321 PF11968.3 AEO69351.1 - 1.9e-92 308.8 0.0 2.4e-92 308.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 AEO69351.1 - 1.8e-05 24.4 0.0 2.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_L23eN PF03939.8 AEO69352.1 - 3e-19 68.7 9.9 3e-19 68.7 6.9 2.1 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 AEO69352.1 - 7.8e-16 57.8 1.6 7.8e-16 57.8 1.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L23 zf-Tim10_DDP PF02953.10 AEO69353.1 - 2.9e-20 71.3 1.0 3.8e-20 70.9 0.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Bclt PF15318.1 AEO69353.1 - 0.028 14.4 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative Bcl-2 like protein of testis CorA PF01544.13 AEO69354.1 - 2.9e-41 141.4 0.0 4e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SPC12 PF06645.8 AEO69355.1 - 5.7e-28 96.5 0.1 6.9e-28 96.2 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MerC PF03203.9 AEO69355.1 - 0.00073 19.8 0.1 0.00087 19.6 0.0 1.1 1 0 0 1 1 1 1 MerC mercury resistance protein PNRC PF15365.1 AEO69356.1 - 0.00012 22.0 6.4 0.00012 22.0 4.5 5.1 5 1 0 5 5 5 2 Proline-rich nuclear receptor coactivator Tyr-DNA_phospho PF06087.7 AEO69357.1 - 1.2e-70 238.4 0.0 1.4e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 AEO69357.1 - 9e-05 22.2 0.0 0.0019 17.9 0.0 2.3 2 0 0 2 2 2 1 PLD-like domain CDP-OH_P_transf PF01066.16 AEO69358.1 - 6.5e-16 58.4 6.0 6.5e-16 58.4 4.1 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GIDA PF01134.17 AEO69359.1 - 1.7e-154 514.4 0.0 2.2e-154 514.0 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 AEO69359.1 - 3.8e-17 62.1 0.1 9.3e-17 60.8 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 SSB PF00436.20 AEO69359.1 - 1.8e-15 56.6 0.0 3e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Single-strand binding protein family FAD_oxidored PF12831.2 AEO69359.1 - 7.6e-08 31.8 0.1 1.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AEO69359.1 - 3.2e-06 27.1 0.2 8.1e-06 25.8 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AEO69359.1 - 0.00034 19.6 0.9 0.7 8.7 0.5 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO69359.1 - 0.00082 18.3 1.7 0.00082 18.3 1.1 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 AEO69359.1 - 0.02 14.4 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 AEO69359.1 - 0.023 13.1 0.8 0.12 10.8 0.6 1.9 2 0 0 2 2 2 0 HI0933-like protein STE3 PF02076.10 AEO69360.1 - 4e-30 104.8 3.9 5e-30 104.5 2.7 1.0 1 0 0 1 1 1 1 Pheromone A receptor Pkinase PF00069.20 AEO69361.1 - 3.3e-58 196.8 0.0 4.6e-58 196.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO69361.1 - 3.4e-20 72.2 0.0 5.3e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO69361.1 - 5.8e-08 32.0 0.0 1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO69361.1 - 0.00042 20.1 1.1 0.00089 19.0 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 AEO69361.1 - 0.0024 17.2 0.1 0.005 16.2 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 AEO69361.1 - 0.0052 15.8 0.3 0.013 14.6 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 AEO69361.1 - 0.096 13.0 0.0 2 8.8 0.0 3.1 3 1 0 3 3 3 0 PAS domain IQ PF00612.22 AEO69362.1 - 0.28 10.9 7.8 38 4.2 0.1 4.6 4 0 0 4 4 4 0 IQ calmodulin-binding motif F-box-like PF12937.2 AEO69364.1 - 4.2e-10 39.1 0.5 2.3e-09 36.8 0.1 2.6 3 0 0 3 3 3 1 F-box-like LRR_6 PF13516.1 AEO69364.1 - 1.9e-08 33.5 1.0 0.056 13.5 0.0 6.1 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.28 AEO69364.1 - 1.6e-06 27.3 2.0 0.082 12.9 0.0 6.1 6 1 0 6 6 6 1 Leucine Rich Repeat F-box PF00646.28 AEO69364.1 - 1.5e-05 24.5 0.1 4.3e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 AEO69364.1 - 4.9e-05 22.8 4.3 1.6 8.4 0.0 5.4 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) CDK2AP PF09806.4 AEO69364.1 - 0.0083 16.3 3.1 0.0083 16.3 2.1 1.9 2 0 0 2 2 2 1 Cyclin-dependent kinase 2-associated protein LRR_7 PF13504.1 AEO69364.1 - 0.0088 16.0 5.5 3.2 8.3 0.1 5.8 6 0 0 6 6 6 1 Leucine rich repeat LRR_8 PF13855.1 AEO69364.1 - 0.011 15.4 1.7 0.092 12.5 0.1 3.2 4 1 0 4 4 4 0 Leucine rich repeat CAF-1_p150 PF11600.3 AEO69364.1 - 0.24 10.7 1.4 0.41 9.9 1.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 AEO69364.1 - 9.1 5.6 15.2 25 4.2 10.6 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein KH_1 PF00013.24 AEO69365.1 - 5.9e-39 131.5 12.0 8.6e-15 54.1 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 AEO69365.1 - 7.8e-30 102.0 13.2 6e-11 41.7 0.6 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 AEO69365.1 - 2.5e-10 39.7 9.1 0.004 16.6 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 AEO69365.1 - 1.6e-08 34.0 3.7 0.031 13.8 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 AEO69365.1 - 0.00062 19.5 5.1 0.64 9.8 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 AEO69365.1 - 0.0075 15.7 0.3 0.5 9.8 0.0 2.9 3 0 0 3 3 3 1 dUTPase UAA PF08449.6 AEO69366.1 - 1.4e-69 234.3 0.7 4.1e-69 232.8 0.5 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 AEO69366.1 - 2.5e-11 43.7 20.8 1.6e-06 28.1 3.1 3.6 4 0 0 4 4 4 3 EamA-like transporter family Nuc_sug_transp PF04142.10 AEO69366.1 - 1.7e-07 30.6 1.0 0.01 14.9 0.0 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 AEO69366.1 - 1.7e-06 28.1 19.5 0.00016 21.8 4.2 3.0 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 AEO69366.1 - 5.5e-05 22.8 3.9 5.5e-05 22.8 2.7 3.0 3 0 0 3 3 3 2 Triose-phosphate Transporter family DSPc PF00782.15 AEO69367.1 - 2.5e-25 88.5 0.0 7.4e-22 77.3 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AEO69367.1 - 0.0021 17.4 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TFIIIC_sub6 PF10419.4 AEO69367.1 - 0.29 10.6 0.5 2.4 7.6 0.1 2.3 2 0 0 2 2 2 0 TFIIIC subunit PTS_2-RNA PF01885.11 AEO69369.1 - 3e-65 219.0 0.0 3.7e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF3628 PF12300.3 AEO69369.1 - 4 7.4 11.2 8.7 6.3 7.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) Dicty_REP PF05086.7 AEO69370.1 - 1.4 6.5 3.6 1.8 6.2 2.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2361 PF10153.4 AEO69371.1 - 8e-30 103.3 21.7 8.1e-16 58.2 3.9 3.1 3 0 0 3 3 3 2 Uncharacterised conserved protein (DUF2361) zf-RING_2 PF13639.1 AEO69372.1 - 0.23 11.3 11.4 0.031 14.1 2.9 2.9 3 0 0 3 3 3 0 Ring finger domain zf-rbx1 PF12678.2 AEO69372.1 - 0.95 9.6 6.5 2.9 8.0 4.5 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AEO69372.1 - 1.1 9.2 11.3 0.059 13.4 1.3 3.0 2 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 AEO69373.1 - 6.3e-08 32.5 19.2 9.4e-06 25.6 2.3 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO69373.1 - 5.5e-05 23.2 2.8 5.5e-05 23.2 2.0 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO69373.1 - 6.6e-05 22.9 16.2 0.00075 19.6 0.4 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO69373.1 - 0.00055 19.9 6.7 0.00079 19.4 0.5 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AEO69373.1 - 0.0012 18.6 1.4 7.2 6.6 0.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 AEO69373.1 - 0.0094 16.1 2.4 0.083 13.1 0.5 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 AEO69373.1 - 5.4 7.1 11.8 10 6.3 5.1 3.1 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) C1_3 PF07649.7 AEO69375.1 - 6.9 6.8 8.5 9.8 6.3 5.9 1.2 1 0 0 1 1 1 0 C1-like domain Glyco_hydro_76 PF03663.9 AEO69376.1 - 1.2e-48 166.3 12.4 3.1e-48 165.0 8.5 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 AEO69376.1 - 7.9e-05 21.8 4.8 0.15 11.0 3.1 2.7 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 Pheromone PF08015.6 AEO69376.1 - 7 7.5 13.9 3.2 8.6 7.4 2.1 2 0 0 2 2 2 0 Fungal mating-type pheromone Glucosamine_iso PF01182.15 AEO69377.1 - 1.2e-61 207.8 0.0 1.5e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hydrolase_6 PF13344.1 AEO69378.1 - 7.9e-29 99.5 0.0 1.3e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AEO69378.1 - 2.3e-14 54.3 0.0 3.6e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO69378.1 - 5.1e-11 42.1 0.0 2.6e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 AEO69378.1 - 5.4e-07 29.9 0.0 0.00035 20.8 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Ribosomal_L7Ae PF01248.21 AEO69378.1 - 0.057 12.9 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Acid_phosphat_B PF03767.9 AEO69378.1 - 0.099 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) SET PF00856.23 AEO69379.1 - 9.2e-08 32.5 0.0 5.7e-06 26.7 0.0 2.7 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 AEO69379.1 - 0.23 11.1 2.7 5.1 6.8 1.7 2.4 2 0 0 2 2 2 0 TPR repeat zf-MYND PF01753.13 AEO69379.1 - 0.75 9.7 10.2 0.041 13.7 2.5 2.4 2 0 0 2 2 2 0 MYND finger DZR PF12773.2 AEO69379.1 - 1.5 8.7 10.8 0.16 11.8 3.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon Stb3 PF10330.4 AEO69380.1 - 8.1e-38 128.0 0.0 1.2e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein Topoisom_bac PF01131.15 AEO69382.1 - 4.7e-91 305.6 0.0 6.4e-86 288.7 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 AEO69382.1 - 4.7e-19 68.2 0.0 8.9e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain RdRP_1 PF00680.15 AEO69382.1 - 0.14 10.3 0.0 0.2 9.8 0.0 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase DUF1295 PF06966.7 AEO69383.1 - 2.2e-38 131.9 5.1 3.7e-38 131.1 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) TFIIA PF03153.8 AEO69384.1 - 0.85 9.4 3.2 0.93 9.3 2.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ashwin PF15323.1 AEO69384.1 - 0.95 9.4 7.8 1.7 8.6 5.4 1.3 1 0 0 1 1 1 0 Developmental protein Pneumo_att_G PF05539.6 AEO69384.1 - 8.2 5.6 19.4 10 5.3 13.4 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF4149 PF13664.1 AEO69385.1 - 7.8e-24 83.6 2.0 2.3e-23 82.1 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Receptor_IA-2 PF11548.3 AEO69385.1 - 0.12 12.3 0.1 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein-tyrosine phosphatase receptor IA-2 Ku_N PF03731.10 AEO69386.1 - 1.2e-25 90.2 0.0 1.9e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 AEO69386.1 - 1.6e-24 86.4 0.0 2.9e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 AEO69386.1 - 1.5e-15 57.1 0.0 3.6e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like VWA_2 PF13519.1 AEO69386.1 - 4.5e-05 23.6 0.0 0.00016 21.7 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 AEO69386.1 - 0.0054 16.4 0.1 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain DnaJ PF00226.26 AEO69388.1 - 1.6e-07 30.9 0.0 2.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 AEO69388.1 - 3.4e-06 26.8 0.0 3.7e-06 26.7 0.0 1.2 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.1 AEO69388.1 - 0.02 14.1 1.1 0.02 14.1 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) TMP_2 PF06791.8 AEO69388.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF3602 PF12223.3 AEO69389.1 - 3.6e-09 36.8 25.4 6.6e-05 23.2 1.8 3.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Mucin PF01456.12 AEO69389.1 - 1.7 8.4 11.9 2.4 7.9 8.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-C2H2 PF00096.21 AEO69391.1 - 0.017 15.4 3.4 0.043 14.1 2.3 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Rib_recp_KP_reg PF05104.7 AEO69391.1 - 0.024 15.1 0.1 0.055 13.9 0.1 1.6 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region zf-C2H2_4 PF13894.1 AEO69391.1 - 0.03 14.6 2.9 0.08 13.3 2.0 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO69391.1 - 0.098 12.9 2.3 13 6.3 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double domain DUF3005 PF11448.3 AEO69392.1 - 0.62 9.6 2.6 1.2 8.7 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3005) Bactofilin PF04519.8 AEO69393.1 - 0.0054 16.7 0.6 0.017 15.1 0.4 1.7 1 1 0 1 1 1 1 Polymer-forming cytoskeletal MinC_C PF03775.11 AEO69393.1 - 0.012 15.1 0.8 0.4 10.3 0.2 2.1 1 1 1 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain DUF342 PF03961.8 AEO69393.1 - 0.063 11.6 1.8 0.075 11.4 0.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) PHD PF00628.24 AEO69394.1 - 1.7e-09 37.2 5.9 2.6e-09 36.6 4.1 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 AEO69394.1 - 0.00093 19.4 0.0 0.0035 17.5 0.0 2.0 1 1 1 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding LMBR1 PF04791.11 AEO69394.1 - 0.91 8.0 0.4 2.3 6.6 0.1 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein SnoaL_4 PF13577.1 AEO69395.1 - 0.0002 21.2 0.1 0.0037 17.1 0.0 2.5 2 1 1 3 3 3 1 SnoaL-like domain DPM2 PF07297.7 AEO69397.1 - 1.6e-36 124.4 2.5 1.9e-36 124.1 1.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 AEO69397.1 - 5.9e-05 22.7 1.0 6.6e-05 22.5 0.7 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 AEO69397.1 - 0.0018 18.1 2.6 0.0018 18.1 1.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) COX14 PF14880.1 AEO69397.1 - 0.0068 16.0 2.7 0.029 14.0 0.0 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF1049 PF06305.6 AEO69397.1 - 0.025 14.0 0.6 0.025 14.0 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF4083 PF13314.1 AEO69397.1 - 0.029 14.1 1.9 0.032 14.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DiS_P_DiS PF06750.8 AEO69397.1 - 0.1 12.3 0.4 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Herpes_UL43 PF05072.8 AEO69397.1 - 2.4 6.8 6.0 0.13 11.0 0.7 1.3 2 0 0 2 2 2 0 Herpesvirus UL43 protein PspC PF04024.7 AEO69397.1 - 2.9 7.4 5.9 15 5.1 0.8 2.2 2 0 0 2 2 2 0 PspC domain TPPK_C PF12555.3 AEO69397.1 - 6.1 6.6 8.5 8 6.2 0.8 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal MIF4G PF02854.14 AEO69398.1 - 1.8e-24 86.3 0.7 1.8e-24 86.3 0.5 1.8 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 AEO69398.1 - 4.9e-22 77.7 0.0 9.2e-22 76.8 0.0 1.5 1 0 0 1 1 1 1 MA3 domain FAM176 PF14851.1 AEO69398.1 - 0.52 9.9 6.3 1.2 8.8 4.4 1.5 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.11 AEO69398.1 - 8.1 5.3 7.8 18 4.2 5.4 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Dus PF01207.12 AEO69399.1 - 3.1e-62 210.1 0.0 6.4e-62 209.1 0.0 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 AEO69399.1 - 0.14 11.1 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Pkinase PF00069.20 AEO69402.1 - 5e-19 68.4 0.0 1.1e-18 67.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO69402.1 - 5.5e-15 55.1 0.0 8.8e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO69402.1 - 1.6e-05 24.0 0.0 2.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO69402.1 - 0.037 13.7 0.6 0.18 11.5 0.3 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_16 PF00722.16 AEO69403.1 - 6.5e-12 45.1 1.9 1e-11 44.4 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WW PF00397.21 AEO69404.1 - 3.3 7.6 11.4 0.78 9.6 2.6 2.9 2 0 0 2 2 2 0 WW domain SSP160 PF06933.6 AEO69404.1 - 4.7 5.0 6.9 10 3.9 4.8 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RIX1 PF08167.7 AEO69405.1 - 5e-45 153.1 0.0 1e-44 152.0 0.0 1.6 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis TPR_8 PF13181.1 AEO69406.1 - 0.0064 16.1 1.2 0.055 13.2 0.0 3.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 AEO69406.1 - 0.0094 15.5 17.2 3.5 7.3 0.1 6.0 4 1 3 7 7 7 2 TPR repeat TPR_14 PF13428.1 AEO69406.1 - 0.011 16.3 1.2 0.011 16.3 0.8 9.4 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_19 PF14559.1 AEO69406.1 - 0.057 13.7 0.3 0.057 13.7 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 AEO69406.1 - 0.068 13.1 31.8 2.5 8.2 0.7 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.1 AEO69406.1 - 0.41 10.5 18.7 18 5.3 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO69406.1 - 2.1 8.0 13.5 43 3.9 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO69406.1 - 5.5 7.6 12.9 2 9.0 0.9 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DHFR_1 PF00186.14 AEO69407.1 - 2.2e-33 115.0 0.0 3.6e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase Ubiq_cyt_C_chap PF03981.7 AEO69408.1 - 1.5e-36 125.3 1.8 2.8e-36 124.4 1.3 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone DUF824 PF05688.6 AEO69408.1 - 0.046 13.3 0.2 0.098 12.3 0.2 1.5 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) ketoacyl-synt PF00109.21 AEO69409.1 - 4.4e-55 186.9 9.4 4.7e-53 180.2 2.7 3.0 2 1 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 AEO69409.1 - 6e-34 116.4 1.5 6e-34 116.4 1.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 AEO69409.1 - 1.8e-05 23.9 0.1 9.6e-05 21.4 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AEO69409.1 - 0.0003 20.2 3.5 0.0014 18.0 0.2 3.2 3 2 0 3 3 3 1 Thiolase, C-terminal domain OPT PF03169.10 AEO69410.1 - 3.4e-189 630.2 45.5 3.9e-189 630.0 31.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 AEO69410.1 - 0.16 11.0 0.8 0.6 9.1 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Dioxygenase_C PF00775.16 AEO69411.1 - 9.4e-54 181.4 0.0 1.3e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase CarboxypepD_reg PF13620.1 AEO69411.1 - 4.8e-05 23.3 0.0 0.0016 18.4 0.0 2.4 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain Fungal_trans PF04082.13 AEO69412.1 - 2.1e-25 89.1 0.0 4.5e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO69412.1 - 1.4e-05 24.9 15.6 2.6e-05 24.0 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mak10 PF04112.8 AEO69412.1 - 0.15 11.2 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Rsm1 PF08600.5 AEO69412.1 - 0.21 11.4 1.9 0.51 10.2 1.3 1.6 1 0 0 1 1 1 0 Rsm1-like CoA_transf_3 PF02515.12 AEO69413.1 - 6.7e-23 80.9 2.5 5.5e-22 77.9 0.5 2.2 2 0 0 2 2 2 2 CoA-transferase family III Biotin_lipoyl PF00364.17 AEO69414.1 - 3.5e-21 74.6 0.6 6.4e-21 73.7 0.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 AEO69414.1 - 6e-09 35.3 0.2 6.6e-08 32.0 0.0 2.8 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 AEO69414.1 - 5.6e-05 22.7 0.0 0.00074 19.1 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 AEO69414.1 - 0.019 14.1 0.2 0.21 10.7 0.2 2.0 1 1 0 1 1 1 0 HlyD family secretion protein HlyD_3 PF13437.1 AEO69414.1 - 0.038 14.3 0.4 1.6 9.1 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein QRPTase_N PF02749.11 AEO69414.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain LRR_4 PF12799.2 AEO69416.1 - 3.3e-16 58.5 4.0 8e-07 28.5 0.7 4.4 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO69416.1 - 2.1e-14 52.9 3.4 8e-09 35.1 2.6 2.8 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 AEO69416.1 - 8.4e-11 40.3 5.6 0.15 12.1 0.2 6.3 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.1 AEO69416.1 - 0.00024 20.8 1.8 34 4.9 0.4 5.2 4 1 1 5 5 5 0 Leucine Rich repeat LRR_7 PF13504.1 AEO69416.1 - 0.00025 20.7 9.3 26 5.6 0.2 5.8 5 0 0 5 5 5 0 Leucine rich repeat Ilar_coat PF01787.11 AEO69416.1 - 5.4 6.5 7.9 0.55 9.7 1.2 2.2 2 0 0 2 2 2 0 Ilarvirus coat protein zf-HC5HC2H_2 PF13832.1 AEO69417.1 - 9.9e-35 118.8 9.6 1.9e-34 117.9 6.6 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 AEO69417.1 - 3e-27 94.5 8.0 3e-27 94.5 5.5 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain GM_CSF PF01109.12 AEO69417.1 - 0.067 13.1 0.2 0.18 11.7 0.1 1.7 1 1 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor zf-RING-like PF08746.6 AEO69417.1 - 2.1 8.4 15.4 0.23 11.4 7.2 1.9 2 0 0 2 2 2 0 RING-like domain Metallophos PF00149.23 AEO69418.1 - 1.4e-44 151.8 0.2 1.7e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WSC PF01822.14 AEO69419.1 - 1.9e-33 114.2 28.6 2.3e-18 65.8 8.0 5.8 6 2 0 6 6 6 2 WSC domain SSP160 PF06933.6 AEO69419.1 - 1.7 6.5 35.2 0.014 13.4 6.4 2.2 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 PCI PF01399.22 AEO69420.1 - 1.6e-09 37.9 0.4 1.4e-08 35.0 0.0 2.7 2 0 0 2 2 2 1 PCI domain G-gamma PF00631.17 AEO69421.1 - 7.4e-27 92.8 0.0 9.4e-27 92.5 0.0 1.1 1 0 0 1 1 1 1 GGL domain Rdx PF10262.4 AEO69422.1 - 6.8e-29 99.7 0.0 8.9e-29 99.3 0.0 1.2 1 0 0 1 1 1 1 Rdx family MBOAT PF03062.14 AEO69423.1 - 9.7e-21 74.2 16.7 1.6e-20 73.5 11.6 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 AEO69423.1 - 9.1e-06 25.6 1.4 2.9e-05 24.0 1.0 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RNA_pol_Rpb6 PF01192.17 AEO69424.1 - 6.5e-23 80.2 0.2 1e-22 79.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.21 AEO69425.1 - 4.8e-28 95.7 40.9 0.00013 22.0 0.1 10.4 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO69425.1 - 3.2e-22 77.1 39.7 0.0041 17.3 0.2 10.2 10 0 0 10 10 10 7 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO69425.1 - 1.6e-14 53.3 48.4 2e-05 24.6 0.3 11.4 11 1 0 11 11 11 4 Zinc-finger double domain DUF4187 PF13821.1 AEO69425.1 - 0.0011 18.5 0.3 0.0074 15.8 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-C2H2_jaz PF12171.3 AEO69425.1 - 0.062 13.4 31.0 0.49 10.6 0.4 7.7 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO69425.1 - 0.13 12.5 27.3 0.29 11.3 0.2 6.7 8 0 0 8 8 8 0 Zinc-finger of C2H2 type SGT1 PF07093.6 AEO69426.1 - 0.00012 20.6 13.4 0.00012 20.6 9.3 1.1 1 0 0 1 1 1 1 SGT1 protein Ycf1 PF05758.7 AEO69426.1 - 5.1 4.6 7.2 5.2 4.6 5.0 1.0 1 0 0 1 1 1 0 Ycf1 Tmemb_170 PF10190.4 AEO69428.1 - 0.0049 16.9 4.6 0.006 16.6 3.2 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 DPM3 PF08285.6 AEO69428.1 - 0.25 11.2 2.0 0.3 10.9 0.4 1.9 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) FtsX PF02687.16 AEO69428.1 - 2.8 7.7 10.0 0.7 9.6 4.2 1.8 1 1 1 2 2 2 0 FtsX-like permease family ICMT PF04140.9 AEO69429.1 - 2.9e-28 97.8 0.1 6.8e-28 96.7 0.1 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 AEO69429.1 - 4.4e-13 49.2 0.8 4.4e-13 49.2 0.6 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 AEO69429.1 - 0.0035 15.9 0.3 0.0064 15.0 0.2 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family NnrU PF07298.6 AEO69429.1 - 0.0091 15.3 6.6 0.042 13.2 4.6 2.1 1 1 0 1 1 1 1 NnrU protein DUF1295 PF06966.7 AEO69429.1 - 0.032 13.5 0.3 0.032 13.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) WD40 PF00400.27 AEO69430.1 - 1.1e-47 158.2 26.7 2.1e-08 33.7 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 AEO69430.1 - 0.0051 15.6 0.0 0.023 13.4 0.0 2.1 2 1 0 2 2 2 1 Nup133 N terminal like eIF2A PF08662.6 AEO69430.1 - 0.1 12.3 0.0 2.3 7.8 0.0 2.4 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A OMP_b-brl PF13505.1 AEO69430.1 - 7.7 6.4 9.1 17 5.3 6.3 1.5 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Endonuclease_NS PF01223.18 AEO69431.1 - 2e-58 197.4 0.0 2.6e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Zip PF02535.17 AEO69432.1 - 3.5e-32 111.6 9.5 1.2e-31 109.9 6.6 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter SNF2_N PF00176.18 AEO69433.1 - 2.9e-84 282.3 1.2 2.9e-84 282.3 0.9 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 AEO69433.1 - 2.1e-20 72.3 0.0 6.8e-20 70.7 0.0 1.9 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 AEO69433.1 - 2.1e-17 63.0 0.8 2.1e-17 63.0 0.6 4.3 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex Helicase_C PF00271.26 AEO69433.1 - 2.3e-17 62.5 0.0 2.3e-17 62.5 0.0 4.4 5 0 0 5 5 5 1 Helicase conserved C-terminal domain HSA PF07529.8 AEO69433.1 - 1.9e-13 49.9 12.1 1.9e-13 49.9 8.4 3.7 4 0 0 4 4 4 1 HSA QLQ PF08880.6 AEO69433.1 - 1.2e-10 40.5 0.5 1.2e-10 40.5 0.3 2.5 2 0 0 2 2 2 1 QLQ WD40 PF00400.27 AEO69434.1 - 2.8e-23 80.8 7.2 6.8e-06 25.7 0.2 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat TFIIF_alpha PF05793.7 AEO69434.1 - 0.0011 17.5 8.4 0.018 13.4 3.7 2.1 2 0 0 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) eIF2A PF08662.6 AEO69434.1 - 0.0077 15.9 0.0 0.29 10.7 0.0 3.2 1 1 3 4 4 4 1 Eukaryotic translation initiation factor eIF2A Cwf_Cwc_15 PF04889.7 AEO69434.1 - 0.23 11.1 6.2 0.52 9.9 4.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Tom22 PF04281.8 AEO69434.1 - 0.48 9.9 4.0 0.95 8.9 2.8 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 BCNT PF07572.7 AEO69436.1 - 8.8e-25 86.4 0.9 1.7e-24 85.5 0.6 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development adh_short PF00106.20 AEO69438.1 - 0.084 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase RNA_pol_I_A49 PF06870.7 AEO69439.1 - 1.6e-80 270.5 0.1 1.9e-80 270.3 0.0 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Dak2 PF02734.12 AEO69439.1 - 0.015 15.0 0.5 0.026 14.1 0.4 1.3 1 0 0 1 1 1 0 DAK2 domain Tad PF13400.1 AEO69439.1 - 1.6 8.8 5.3 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like AAA PF00004.24 AEO69440.1 - 1.5e-51 174.0 0.0 1.8e-42 144.7 0.0 3.1 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 AEO69440.1 - 8.5e-07 28.5 0.0 6.1e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 AEO69440.1 - 1.2e-06 28.6 0.1 6.3e-05 23.0 0.1 3.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AEO69440.1 - 1.6e-05 25.0 0.1 0.001 19.1 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 AEO69440.1 - 2.3e-05 24.3 0.0 5.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 AEO69440.1 - 0.00011 21.9 0.2 0.0051 16.5 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AEO69440.1 - 0.00023 21.0 0.0 0.0096 15.7 0.0 3.3 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 AEO69440.1 - 0.0035 16.4 0.0 0.032 13.2 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 AEO69440.1 - 0.0049 16.7 0.0 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain Bromodomain PF00439.20 AEO69440.1 - 0.0055 16.6 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 Bromodomain AAA_17 PF13207.1 AEO69440.1 - 0.0056 17.4 1.9 0.027 15.2 0.0 3.3 4 0 0 4 4 1 1 AAA domain TIP49 PF06068.8 AEO69440.1 - 0.0061 15.3 0.0 0.015 14.0 0.0 1.5 2 0 0 2 2 2 1 TIP49 C-terminus Sigma54_activ_2 PF14532.1 AEO69440.1 - 0.0073 16.3 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.17 AEO69440.1 - 0.01 16.0 0.0 0.028 14.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 AEO69440.1 - 0.014 14.5 0.2 0.13 11.3 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 AEO69440.1 - 0.026 14.8 2.5 0.055 13.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 AEO69440.1 - 0.032 13.9 0.1 0.032 13.9 0.1 4.0 4 0 0 4 4 3 0 Part of AAA domain Parvo_NS1 PF01057.12 AEO69440.1 - 0.033 13.0 0.0 0.19 10.5 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 AEO69440.1 - 0.041 13.5 1.1 0.21 11.2 0.1 2.7 3 1 0 3 3 3 0 NACHT domain AAA_3 PF07726.6 AEO69440.1 - 0.044 13.3 0.0 0.35 10.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 AEO69440.1 - 0.046 13.1 0.1 0.15 11.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 AEO69440.1 - 0.05 13.0 0.0 3.4 7.1 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain Torsin PF06309.6 AEO69440.1 - 0.081 12.8 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Torsin AAA_5 PF07728.9 AEO69441.1 - 5.2e-16 58.6 0.0 3.8e-06 26.6 0.0 3.9 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AEO69441.1 - 0.00085 19.4 0.6 0.12 12.5 0.0 4.2 4 1 0 4 4 4 1 AAA domain Arch_ATPase PF01637.13 AEO69441.1 - 0.0018 18.0 0.0 0.0068 16.1 0.0 2.0 1 0 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 AEO69441.1 - 0.0045 16.4 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 AEO69441.1 - 0.011 15.6 0.0 0.055 13.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain Ribosomal_L12 PF00542.14 AEO69443.1 - 4.1e-20 71.5 6.3 4.5e-19 68.2 2.9 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 AEO69443.1 - 0.0019 18.5 7.8 0.0019 18.5 5.4 2.3 3 1 0 3 3 3 1 60s Acidic ribosomal protein CTK3 PF12243.3 AEO69444.1 - 3.5e-59 198.4 1.7 4.6e-59 198.0 1.1 1.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 AEO69444.1 - 8.5e-22 76.9 11.5 1.9e-21 75.8 7.9 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus P5CR_dimer PF14748.1 AEO69445.1 - 6.7e-35 119.3 2.7 7.2e-35 119.2 1.0 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 AEO69445.1 - 3.1e-14 53.1 3.1 2.4e-12 47.1 0.1 2.7 1 1 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.12 AEO69445.1 - 0.0049 15.7 0.1 0.019 13.8 0.0 1.8 1 1 0 1 1 1 1 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.18 AEO69445.1 - 0.2 11.3 3.1 0.63 9.7 2.1 1.9 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 AEO69445.1 - 0.34 10.3 0.0 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Hat1_N PF10394.4 AEO69446.1 - 1.9e-40 138.5 0.0 4.2e-40 137.4 0.0 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus ROKNT PF08067.6 AEO69446.1 - 3 7.7 6.3 0.91 9.4 2.1 1.9 1 1 1 2 2 2 0 ROKNT (NUC014) domain Zip PF02535.17 AEO69447.1 - 2.6e-33 115.4 2.1 5.4e-32 111.0 1.4 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter WD40 PF00400.27 AEO69449.1 - 5.3e-51 168.7 21.3 7.5e-11 41.4 0.4 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 AEO69449.1 - 1.2e-12 47.3 0.8 2.7e-12 46.2 0.5 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 AEO69449.1 - 7.1e-09 34.3 12.9 0.048 11.8 0.1 5.4 1 1 4 5 5 5 5 Nucleoporin Nup120/160 F-box PF00646.28 AEO69449.1 - 1.2e-05 24.7 1.6 2.5e-05 23.8 1.1 1.6 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 AEO69449.1 - 0.054 12.2 0.3 0.29 9.8 0.1 2.0 1 1 0 2 2 2 0 Nup133 N terminal like PQQ_3 PF13570.1 AEO69449.1 - 0.29 11.4 6.0 21 5.5 0.1 4.5 3 1 1 4 4 4 0 PQQ-like domain CAP_N PF01213.14 AEO69449.1 - 0.29 10.3 2.9 0.64 9.2 1.8 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal E1_dh PF00676.15 AEO69450.1 - 3.5e-113 377.2 0.2 4.5e-113 376.9 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 AEO69450.1 - 0.0015 17.5 0.0 0.0024 16.8 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DNA_ligase_A_M PF01068.16 AEO69451.1 - 3.8e-58 196.1 0.8 9.9e-47 158.9 0.2 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 AEO69451.1 - 7.9e-54 182.1 0.0 1.6e-53 181.1 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 AEO69451.1 - 3.4e-27 94.6 0.3 1e-26 93.1 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region FAD-oxidase_C PF02913.14 AEO69453.1 - 3.3e-61 206.7 0.0 4.6e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 AEO69453.1 - 1.2e-37 128.4 0.3 2e-37 127.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Proteasome PF00227.21 AEO69455.1 - 6.4e-56 188.6 0.1 9.8e-56 188.0 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AEO69455.1 - 1.8e-12 46.3 0.1 1.8e-12 46.3 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature zf-CHY PF05495.7 AEO69456.1 - 7.9e-14 51.5 18.0 9.8e-14 51.2 12.5 1.1 1 0 0 1 1 1 1 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 AEO69456.1 - 0.11 12.3 13.7 1.1 9.1 6.7 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Cytochrome_C7 PF14522.1 AEO69456.1 - 2.2 8.0 11.6 3.3 7.4 8.0 1.3 1 0 0 1 1 1 0 Cytochrome c7 zf-TFIIB PF13453.1 AEO69456.1 - 3.1 7.0 8.4 6.5 6.0 0.0 2.6 2 1 0 2 2 2 0 Transcription factor zinc-finger zf-ribbon_3 PF13248.1 AEO69456.1 - 3.9 6.8 12.2 3.9e+02 0.4 8.5 2.5 1 1 0 1 1 1 0 zinc-ribbon domain Tmemb_55A PF09788.4 AEO69456.1 - 3.9 6.5 8.0 4.6 6.2 5.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A Zn-ribbon_8 PF09723.5 AEO69456.1 - 4.5 7.3 19.3 1.9 8.5 5.7 2.4 2 1 0 2 2 2 0 Zinc ribbon domain HypA PF01155.14 AEO69456.1 - 4.7 6.9 12.2 56 3.4 8.5 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 AEO69456.1 - 6.8 6.3 11.1 2.2 7.8 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain DUF3797 PF12677.2 AEO69456.1 - 6.9 6.3 8.9 3.9 7.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) zf-RING_3 PF14369.1 AEO69456.1 - 7.5 6.6 16.3 1 9.4 5.1 2.8 2 1 1 3 3 3 0 zinc-finger Elf1 PF05129.8 AEO69456.1 - 8.2 6.1 11.1 67 3.2 7.7 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Helicase_C_3 PF13625.1 AEO69457.1 - 9.8e-27 93.2 0.0 7.6e-26 90.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO69457.1 - 4e-16 59.3 0.0 9.4e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AEO69457.1 - 4.9e-11 42.3 0.0 1.3e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AEO69457.1 - 4e-10 38.9 0.0 7e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1719 PF08224.6 AEO69457.1 - 0.028 13.4 0.0 0.32 10.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1719) DUF3045 PF11243.3 AEO69457.1 - 0.11 12.7 0.0 0.82 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3045) TrkH PF02386.11 AEO69458.1 - 8.1e-120 399.6 20.0 5.6e-118 393.5 7.0 2.1 2 0 0 2 2 2 2 Cation transport protein Ribosomal_L19 PF01245.15 AEO69459.1 - 3.7e-16 58.8 0.1 6.2e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 K_channel_TID PF07941.6 AEO69459.1 - 1.4 9.2 8.2 2.6 8.3 5.6 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain PALP PF00291.20 AEO69461.1 - 1.7e-60 204.8 0.0 2.3e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme YL1 PF05764.8 AEO69462.1 - 3.1e-59 200.4 30.1 3.1e-59 200.4 20.9 2.8 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 AEO69462.1 - 2.8e-15 55.5 1.2 4.6e-15 54.8 0.8 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.11 AEO69462.1 - 0.2 11.3 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 HIT zinc finger Mis12 PF05859.7 AEO69463.1 - 1.3e-32 112.5 0.0 3.9e-32 111.0 0.0 1.9 1 1 0 1 1 1 1 Mis12 protein PBP1_TM PF14812.1 AEO69463.1 - 0.41 10.9 6.8 0.29 11.4 0.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRM_6 PF14259.1 AEO69464.1 - 5.4e-41 138.4 0.0 1.2e-11 44.3 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO69464.1 - 1.4e-39 133.5 0.1 1e-12 47.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO69464.1 - 4.7e-21 74.3 0.1 8.4e-06 25.5 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 AEO69464.1 - 2.7e-13 49.2 5.8 2.7e-13 49.2 4.0 2.7 2 0 0 2 2 2 1 Putative RRM domain RRM_3 PF08777.6 AEO69464.1 - 0.00036 20.3 2.2 0.039 13.8 0.1 2.9 3 0 0 3 3 3 1 RNA binding motif DUF4523 PF15023.1 AEO69464.1 - 0.02 14.3 0.0 8.8 5.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) RNA_bind PF08675.6 AEO69464.1 - 0.026 14.4 0.0 0.3 11.1 0.0 2.6 2 1 0 2 2 2 0 RNA binding domain Nup35_RRM_2 PF14605.1 AEO69464.1 - 0.078 12.7 0.0 29 4.5 0.0 3.3 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif tRNA-synt_2 PF00152.15 AEO69465.1 - 3e-70 236.6 0.0 5.6e-70 235.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AEO69465.1 - 3.1e-05 23.7 0.0 5.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain XkdW PF09636.5 AEO69465.1 - 0.16 11.8 1.9 0.34 10.7 1.3 1.5 1 0 0 1 1 1 0 XkdW protein Ras PF00071.17 AEO69466.1 - 5.4e-53 178.6 0.0 6.3e-53 178.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO69466.1 - 5.1e-16 59.2 0.0 1.2e-15 58.0 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AEO69466.1 - 1.2e-05 24.6 0.0 1.7e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Hid1 PF12722.2 AEO69467.1 - 3.8 5.0 5.5 4.2 4.9 3.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.12 AEO69467.1 - 4.2 6.0 5.2 5.2 5.7 3.6 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.4 AEO69467.1 - 6.3 4.9 8.9 8 4.5 6.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Dicty_REP PF05086.7 AEO69467.1 - 6.9 4.2 6.7 9.3 3.8 4.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1675 PF07897.6 AEO69467.1 - 7.5 6.3 11.9 9.8 5.9 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) His_Phos_2 PF00328.17 AEO69468.1 - 2.8e-23 82.8 0.0 1.7e-21 76.9 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Chorion_S16 PF05836.7 AEO69468.1 - 0.091 12.6 0.3 0.45 10.4 0.1 2.2 3 0 0 3 3 3 0 Chorion protein S16 PPR_2 PF13041.1 AEO69469.1 - 1.9e-21 75.7 0.0 8.9e-05 22.3 0.0 6.5 5 1 1 6 6 6 4 PPR repeat family PPR_3 PF13812.1 AEO69469.1 - 1.7e-15 55.8 4.4 0.26 11.6 0.0 9.5 10 0 0 10 10 10 4 Pentatricopeptide repeat domain PPR PF01535.15 AEO69469.1 - 1.2e-14 53.2 0.0 0.21 11.6 0.0 6.2 5 0 0 5 5 5 5 PPR repeat PPR_1 PF12854.2 AEO69469.1 - 1.9e-05 23.9 7.8 0.075 12.5 0.0 5.4 6 0 0 6 6 6 2 PPR repeat TPR_19 PF14559.1 AEO69469.1 - 0.024 14.9 1.5 0.3 11.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO69469.1 - 2.9 8.7 22.3 6.4 7.7 0.7 6.5 9 0 0 9 9 9 0 Tetratricopeptide repeat FYDLN_acid PF09538.5 AEO69470.1 - 4.7 7.8 12.8 11 6.6 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) FA_hydroxylase PF04116.8 AEO69471.1 - 3.2e-15 56.5 11.5 3.2e-15 56.5 8.0 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TCTP PF00838.12 AEO69472.1 - 5.5e-68 228.1 4.4 6.2e-68 227.9 3.0 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein DUF1918 PF08940.6 AEO69472.1 - 0.03 13.6 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) GGGtGRT PF14057.1 AEO69472.1 - 0.08 11.7 0.2 0.097 11.4 0.2 1.2 1 0 0 1 1 1 0 GGGtGRT protein Voltage_CLC PF00654.15 AEO69473.1 - 1.3e-91 307.2 27.5 1.3e-91 307.2 19.1 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 AEO69473.1 - 1.2e-06 28.2 0.0 0.0025 17.5 0.0 2.9 2 1 1 3 3 3 2 CBS domain Neurochondrin PF05536.6 AEO69474.1 - 3.3e-118 395.3 0.0 3.7e-117 391.9 0.0 2.0 1 1 0 1 1 1 1 Neurochondrin Ric8 PF10165.4 AEO69474.1 - 0.01 14.7 0.1 4.7 5.9 0.0 2.7 3 0 0 3 3 3 2 Guanine nucleotide exchange factor synembryn RIX1 PF08167.7 AEO69474.1 - 0.075 12.7 1.1 0.58 9.8 0.1 3.1 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis Rotamase_3 PF13616.1 AEO69475.1 - 4.7e-19 68.7 0.0 6.6e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 AEO69475.1 - 7.8e-18 65.0 0.3 1.2e-17 64.4 0.0 1.4 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 AEO69475.1 - 3.9e-05 24.2 0.0 5.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain DUF1140 PF06600.6 AEO69475.1 - 0.015 15.4 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) Ribosomal_L7Ae PF01248.21 AEO69476.1 - 8.7e-29 98.8 0.7 1e-28 98.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 AEO69476.1 - 0.063 12.8 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Ribosomal_S8 PF00410.14 AEO69477.1 - 5.8e-26 90.8 0.0 7.8e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Glyco_transf_90 PF05686.7 AEO69478.1 - 1.7e-09 36.8 5.8 0.056 12.1 0.0 4.6 4 1 0 4 4 4 4 Glycosyl transferase family 90 Paf1 PF03985.8 AEO69479.1 - 2.2e-59 201.3 4.0 3.1e-59 200.8 2.8 1.2 1 1 0 1 1 1 1 Paf1 Cylicin_N PF15241.1 AEO69479.1 - 0.054 13.3 0.5 0.13 12.1 0.3 1.6 1 0 0 1 1 1 0 Cylicin N-terminus BTV_NS2 PF04514.7 AEO69479.1 - 2.4 6.9 11.8 3.9 6.2 8.1 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Rer1 PF03248.8 AEO69480.1 - 1.5e-79 265.6 6.3 1.7e-79 265.5 4.4 1.0 1 0 0 1 1 1 1 Rer1 family ECH PF00378.15 AEO69481.1 - 1.2e-68 230.8 0.1 1.5e-68 230.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 AEO69481.1 - 0.012 15.7 0.1 0.038 14.1 0.0 1.8 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region zf-C3HC4 PF00097.20 AEO69482.1 - 1.1e-07 31.3 3.1 1.1e-07 31.3 2.1 5.1 6 0 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO69482.1 - 2.7e-07 30.2 5.1 2.7e-07 30.2 3.5 4.3 5 0 0 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO69482.1 - 8.1e-06 25.7 2.8 8.1e-06 25.7 1.9 6.2 5 3 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO69482.1 - 6.1e-05 22.6 2.8 6.1e-05 22.6 1.9 5.5 6 0 0 6 6 6 1 zinc-RING finger domain zf-RING_6 PF14835.1 AEO69482.1 - 7.2e-05 22.4 0.4 7.2e-05 22.4 0.3 3.8 4 0 0 4 4 4 2 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 AEO69482.1 - 0.00022 21.0 4.4 0.00022 21.0 3.0 4.8 7 1 0 7 7 7 1 zinc finger of C3HC4-type, RING SH3_1 PF00018.23 AEO69482.1 - 0.0005 19.4 0.1 0.0012 18.1 0.0 1.7 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AEO69482.1 - 0.0012 18.3 0.2 0.0012 18.3 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain zf-RING_UBOX PF13445.1 AEO69482.1 - 0.0035 17.0 1.5 0.0087 15.7 1.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Lipase_3 PF01764.20 AEO69483.1 - 1e-06 28.4 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 AEO69483.1 - 0.043 13.5 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 AEO69483.1 - 0.24 11.1 0.0 0.44 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) VPS9 PF02204.13 AEO69484.1 - 3.8e-24 84.6 0.0 7.1e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CH PF00307.26 AEO69485.1 - 7.2e-40 135.3 0.5 2.8e-19 69.1 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 AEO69485.1 - 3.8e-27 94.0 0.1 1.3e-26 92.2 0.0 2.0 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 AEO69485.1 - 1.5e-12 46.9 1.0 2.1e-07 30.4 0.1 2.9 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 AEO69485.1 - 1.6e-05 24.3 0.3 0.0003 20.4 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain Spectrin PF00435.16 AEO69485.1 - 1.7e-05 25.0 3.6 0.0033 17.6 1.5 2.6 2 0 0 2 2 2 2 Spectrin repeat EF-hand_8 PF13833.1 AEO69485.1 - 9.3e-05 21.9 0.4 0.0014 18.1 0.0 2.8 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 AEO69485.1 - 0.00015 20.8 0.1 0.0013 17.8 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 AEO69485.1 - 0.0003 20.8 1.3 0.0016 18.4 0.9 2.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 AEO69485.1 - 0.043 13.1 0.0 0.11 11.8 0.0 1.8 1 0 0 1 1 1 0 EF hand DUF1943 PF09172.6 AEO69485.1 - 0.063 12.1 0.1 0.14 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) TruD PF01142.13 AEO69486.1 - 5.3e-53 180.0 0.0 1.8e-49 168.4 0.0 3.2 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) Pkinase PF00069.20 AEO69488.1 - 2.3e-60 203.9 0.0 2.8e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO69488.1 - 7.5e-35 120.2 0.0 9.8e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO69488.1 - 1.5e-08 33.9 0.0 2.3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 AEO69488.1 - 0.18 10.5 0.1 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 DEAD PF00270.24 AEO69489.1 - 5.5e-42 143.1 0.0 2e-41 141.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO69489.1 - 1.5e-27 95.2 0.1 3.1e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AEO69489.1 - 2.3e-05 23.3 0.0 3.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Med3 PF11593.3 AEO69489.1 - 1.2 8.3 10.3 1.8 7.7 7.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Amidohydro_2 PF04909.9 AEO69490.1 - 0.011 15.2 0.2 0.018 14.5 0.1 1.4 1 1 0 1 1 1 0 Amidohydrolase APH PF01636.18 AEO69491.1 - 1e-14 54.8 0.1 2.1e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO69491.1 - 0.0027 17.3 0.0 0.018 14.6 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase DnaJ PF00226.26 AEO69492.1 - 2.8e-12 46.1 0.4 9.3e-12 44.5 0.3 2.0 1 0 0 1 1 1 1 DnaJ domain Mucin PF01456.12 AEO69492.1 - 1 9.1 19.4 0.047 13.4 9.3 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF4207 PF13904.1 AEO69492.1 - 1.6 8.0 26.0 0.28 10.5 8.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4207) BBP1_C PF15272.1 AEO69492.1 - 1.7 8.1 12.8 0.028 13.9 1.5 2.4 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal DUF3439 PF11921.3 AEO69492.1 - 1.7 8.4 7.6 0.63 9.7 3.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 AEO69492.1 - 1.7 6.3 7.9 2.1 5.9 5.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein OrfB_IS605 PF01385.14 AEO69492.1 - 2.2 7.6 6.8 0.15 11.4 0.6 2.0 2 0 0 2 2 2 0 Probable transposase ARGLU PF15346.1 AEO69492.1 - 3.1 7.5 41.2 3.6 7.3 3.8 3.3 3 0 0 3 3 3 0 Arginine and glutamate-rich 1 GET2 PF08690.5 AEO69492.1 - 3.9 6.6 10.3 7 5.7 7.1 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Cwf_Cwc_15 PF04889.7 AEO69492.1 - 6.6 6.3 29.6 0.24 11.0 13.9 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GCV_T PF01571.16 AEO69493.1 - 1.3e-13 50.7 0.0 4.8e-13 48.9 0.0 1.9 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 AEO69493.1 - 0.039 13.9 0.0 0.098 12.6 0.0 1.7 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Pkinase PF00069.20 AEO69494.1 - 2.7e-29 102.1 0.0 3.9e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO69494.1 - 3.6e-10 39.3 0.1 5.9e-09 35.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO69494.1 - 0.053 13.2 2.3 0.37 10.4 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family BUD22 PF09073.5 AEO69495.1 - 1.3 8.0 16.0 2.1 7.3 11.1 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.7 AEO69495.1 - 1.8 7.7 15.3 2.4 7.3 10.6 1.2 1 0 0 1 1 1 0 SDA1 DUF3237 PF11578.3 AEO69496.1 - 3.9e-05 22.9 0.0 6.6e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) Pkinase PF00069.20 AEO69497.1 - 9.2e-14 51.2 0.0 1.1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 AEO69497.1 - 0.00045 19.2 0.0 0.00053 19.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 AEO69497.1 - 0.0039 16.2 0.0 0.0054 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO69497.1 - 0.005 16.6 0.2 0.053 13.2 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AEO69497.1 - 0.16 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Septin PF00735.13 AEO69498.1 - 4.5e-18 65.2 0.0 1.1e-16 60.6 0.0 2.7 2 1 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 AEO69498.1 - 8.9e-05 22.4 0.0 0.00043 20.2 0.0 2.2 1 1 1 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 AEO69498.1 - 0.00068 20.1 0.2 0.0021 18.5 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 AEO69498.1 - 0.005 17.0 0.1 0.014 15.6 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 AEO69498.1 - 0.0053 15.9 0.0 0.015 14.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 AEO69498.1 - 0.0073 16.4 0.2 0.026 14.6 0.1 2.0 2 0 0 2 2 1 1 AAA domain MCM PF00493.18 AEO69498.1 - 0.0083 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family AAA_29 PF13555.1 AEO69498.1 - 0.0094 15.4 0.3 0.043 13.3 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 AEO69498.1 - 0.013 15.0 0.1 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.1 AEO69498.1 - 0.015 14.9 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 AEO69498.1 - 0.022 14.5 0.6 0.082 12.7 0.0 2.3 2 1 0 2 2 2 0 Dynamin family AAA_16 PF13191.1 AEO69498.1 - 0.024 14.6 0.1 0.024 14.6 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain Gtr1_RagA PF04670.7 AEO69498.1 - 0.036 13.2 0.1 4.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF815 PF05673.8 AEO69498.1 - 0.049 12.5 0.1 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 AEO69498.1 - 0.075 13.3 0.2 0.26 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 AEO69498.1 - 0.081 12.5 0.1 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 AEO69498.1 - 0.092 12.4 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.22 AEO69498.1 - 0.11 12.8 0.0 0.11 12.8 0.0 2.1 3 0 0 3 3 2 0 ABC transporter MobB PF03205.9 AEO69498.1 - 0.15 11.7 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.21 AEO69498.1 - 0.19 11.2 0.0 0.39 10.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 AEO69498.1 - 0.19 12.5 0.2 0.44 11.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain DUF4603 PF15376.1 AEO69498.1 - 2.5 5.1 8.5 3.8 4.5 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) MIP-T3 PF10243.4 AEO69499.1 - 0.00033 19.2 55.8 0.00033 19.2 38.7 3.1 2 1 1 3 3 3 1 Microtubule-binding protein MIP-T3 zf-C3HC4_3 PF13920.1 AEO69499.1 - 0.0015 18.1 11.7 0.0024 17.4 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 AEO69499.1 - 0.053 13.3 6.9 0.086 12.6 4.8 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 AEO69499.1 - 1.2 8.9 13.3 1.8 8.3 9.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO69499.1 - 2.5 8.1 14.1 4 7.5 9.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ras PF00071.17 AEO69500.1 - 4.2e-58 195.2 0.0 5e-58 195.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO69500.1 - 3.4e-20 72.7 0.0 5.1e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO69500.1 - 3.3e-13 49.2 0.0 5.6e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AEO69500.1 - 4.5e-06 26.2 0.0 1.1e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AEO69500.1 - 2.7e-05 23.4 0.0 3.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AEO69500.1 - 0.00012 22.0 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 AEO69500.1 - 0.0083 16.1 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AEO69500.1 - 0.043 13.9 0.0 0.22 11.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain Kri1_C PF12936.2 AEO69501.1 - 9.5e-27 92.7 0.5 9.5e-27 92.7 0.3 4.1 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 AEO69501.1 - 2e-26 92.2 24.5 2e-26 92.2 17.0 5.3 6 1 0 6 6 6 1 KRI1-like family Fungal_trans PF04082.13 AEO69502.1 - 1.5e-28 99.4 0.0 6.7e-28 97.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO69502.1 - 2e-09 37.1 10.8 3.1e-09 36.5 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RVT_1 PF00078.22 AEO69503.1 - 0.069 12.4 0.1 0.084 12.2 0.1 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) GSH_synthase PF03199.10 AEO69504.1 - 0.097 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic glutathione synthase DUF4306 PF14154.1 AEO69504.1 - 0.18 11.7 1.3 1 9.3 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4306) adh_short PF00106.20 AEO69505.1 - 0.00016 21.6 0.0 0.00041 20.2 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO69505.1 - 0.004 16.8 0.0 0.0094 15.6 0.0 1.6 1 0 0 1 1 1 1 KR domain Zn_clus PF00172.13 AEO69506.1 - 0.0035 17.2 12.8 0.0064 16.3 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C50 PF03568.12 AEO69508.1 - 3.3e-102 342.0 0.0 1.1e-101 340.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 AEO69508.1 - 1.2e-08 34.7 35.5 8.6e-06 25.6 0.8 8.3 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 AEO69508.1 - 0.019 14.7 3.0 3.1 7.8 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4520 PF15016.1 AEO69508.1 - 0.027 14.0 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) TPR_8 PF13181.1 AEO69508.1 - 0.039 13.7 9.1 21 5.1 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO69508.1 - 0.12 12.0 5.6 63 3.4 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat RAMP4 PF06624.7 AEO69509.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 DUF2649 PF10854.3 AEO69509.1 - 0.074 13.1 0.3 0.1 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) SIR2 PF02146.12 AEO69510.1 - 5.3e-27 94.6 0.0 8.1e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Cation_efflux PF01545.16 AEO69511.1 - 2.7e-56 190.7 1.3 3.8e-56 190.2 0.9 1.1 1 0 0 1 1 1 1 Cation efflux family Voltage_CLC PF00654.15 AEO69512.1 - 4.2e-94 315.4 19.5 4.2e-94 315.4 13.5 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel NRDE-2 PF08424.5 AEO69513.1 - 2.8e-74 249.9 0.0 1.2e-71 241.2 0.0 2.7 2 1 0 2 2 2 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 AEO69513.1 - 0.01 16.3 15.4 6.8 7.6 0.1 7.0 5 1 0 5 5 5 0 Tetratricopeptide repeat Whi5 PF08528.6 AEO69514.1 - 1.8e-10 40.0 0.0 3.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Peptidase_M18 PF02127.10 AEO69516.1 - 7.5e-165 548.6 0.0 8.9e-165 548.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 AEO69516.1 - 1.8e-05 23.6 0.0 0.00019 20.2 0.0 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Xpo1 PF08389.7 AEO69518.1 - 1.4e-36 125.6 0.9 3.4e-35 121.1 0.0 3.5 4 1 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.17 AEO69518.1 - 0.021 14.8 1.3 54 4.2 0.0 5.0 4 0 0 4 4 4 0 HEAT repeat NAAA-beta PF15508.1 AEO69518.1 - 0.24 11.7 1.4 35 4.8 0.0 4.4 5 0 0 5 5 5 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase SSrecog PF03531.9 AEO69519.1 - 9.5e-75 250.7 0.1 3.8e-74 248.7 0.1 1.9 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 AEO69519.1 - 3.5e-25 87.8 0.1 2.3e-24 85.1 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF2201_N PF13203.1 AEO69519.1 - 0.17 10.9 0.1 0.17 10.9 0.0 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain TFIIA PF03153.8 AEO69519.1 - 4.1 7.2 16.3 10 5.9 11.4 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit GFA PF04828.9 AEO69520.1 - 0.0032 17.3 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 AEO69520.1 - 0.069 12.3 0.5 0.14 11.3 0.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain CD99L2 PF12301.3 AEO69520.1 - 0.086 12.5 3.0 0.1 12.3 0.8 1.8 1 1 1 2 2 2 0 CD99 antigen like protein 2 Glyco_hydro_1 PF00232.13 AEO69521.1 - 2.1e-153 510.7 0.0 2.5e-153 510.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Mg_trans_NIPA PF05653.9 AEO69522.1 - 1e-61 208.5 8.6 4.6e-59 199.8 3.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 AEO69522.1 - 0.0036 17.4 1.5 0.0036 17.4 1.0 3.9 4 1 0 4 4 4 1 Multidrug resistance efflux transporter DUF914 PF06027.7 AEO69522.1 - 0.028 13.2 5.4 0.29 9.9 0.4 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 AEO69522.1 - 3.8 7.5 24.5 0.28 11.2 2.3 3.9 3 1 1 4 4 4 0 EamA-like transporter family F-box PF00646.28 AEO69522.1 - 6.5 6.5 5.9 1.4 8.6 1.3 1.9 2 0 0 2 2 2 0 F-box domain RRM_1 PF00076.17 AEO69524.1 - 2.3e-59 196.9 0.0 2.9e-18 65.2 0.0 5.9 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO69524.1 - 2.4e-44 149.1 0.0 3.7e-13 49.2 0.0 6.2 6 0 0 6 6 6 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO69524.1 - 5.3e-19 67.8 0.4 5.3e-07 29.3 0.0 4.5 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SGT1 PF07093.6 AEO69524.1 - 0.00032 19.2 17.5 0.00049 18.6 12.1 1.4 1 0 0 1 1 1 1 SGT1 protein Cnd3 PF12719.2 AEO69525.1 - 7.9e-95 317.2 0.2 8.1e-94 313.9 0.0 2.5 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 AEO69525.1 - 3.5e-12 46.4 8.7 5.3e-06 26.6 0.8 4.9 2 1 2 4 4 4 4 HEAT repeats HEAT PF02985.17 AEO69525.1 - 2e-06 27.3 10.0 0.096 12.8 0.0 7.2 7 0 0 7 7 7 1 HEAT repeat DUF1546 PF07571.8 AEO69525.1 - 0.016 15.2 0.5 0.81 9.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) MMS19_N PF14500.1 AEO69525.1 - 0.024 13.9 0.4 0.34 10.1 0.0 2.8 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Phosphodiest PF01663.17 AEO69526.1 - 2.4e-17 63.3 1.1 1.7e-16 60.5 0.8 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 AEO69526.1 - 7.9e-06 25.2 0.0 0.00027 20.2 0.0 2.2 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 AEO69526.1 - 8.7e-06 25.3 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily PigN PF04987.9 AEO69526.1 - 0.00086 18.0 0.0 0.00086 18.0 0.0 3.1 2 1 0 3 3 3 1 Phosphatidylinositolglycan class N (PIG-N) DUF4611 PF15387.1 AEO69526.1 - 0.046 13.8 3.0 0.1 12.7 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF2423 PF10338.4 AEO69527.1 - 3.5e-18 65.3 4.1 3.5e-18 65.3 2.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) HMG14_17 PF01101.13 AEO69527.1 - 4.6 7.9 18.0 0.29 11.8 2.1 2.5 1 1 2 3 3 3 0 HMG14 and HMG17 PINIT PF14324.1 AEO69528.1 - 2.2e-45 154.2 0.1 3.8e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 AEO69528.1 - 7.1e-22 76.6 6.1 1.3e-21 75.8 4.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 AEO69528.1 - 1.9e-06 27.2 0.0 3.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 AEO69528.1 - 1.5e-05 24.4 1.4 3.5e-05 23.2 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.10 AEO69528.1 - 0.058 12.9 2.8 0.14 11.7 1.1 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-C3HC4_4 PF15227.1 AEO69528.1 - 0.13 12.1 5.0 0.27 11.1 3.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 AEO69528.1 - 0.48 10.2 3.4 0.93 9.2 2.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 AEO69528.1 - 1 9.2 4.9 1.9 8.3 3.4 1.5 1 0 0 1 1 1 0 Ring finger domain TRAPP PF04051.11 AEO69529.1 - 2.2e-44 150.6 0.0 2.4e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PorB PF11565.3 AEO69529.1 - 0.0016 18.5 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 Alpha helical Porin B Ldh_1_C PF02866.13 AEO69530.1 - 7.7e-45 152.7 0.0 1.1e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 AEO69530.1 - 3.6e-43 146.7 0.1 5.1e-43 146.2 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 AEO69530.1 - 0.00056 18.7 0.0 0.0017 17.1 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 AEO69530.1 - 0.065 12.5 0.1 3.7 6.8 0.0 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Ribosomal_L28e PF01778.12 AEO69531.1 - 1.5e-38 131.7 0.4 2.1e-38 131.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2015 PF09435.5 AEO69532.1 - 5e-49 165.3 0.0 5.6e-49 165.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) WD40 PF00400.27 AEO69533.1 - 1.5e-69 227.5 11.4 1.2e-10 40.8 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 AEO69533.1 - 1.1e-24 86.3 8.8 1.7e-24 85.7 6.1 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 AEO69533.1 - 0.00011 20.5 3.2 1.1 7.2 0.0 4.4 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AEO69533.1 - 0.0025 16.6 0.1 1.1 7.9 0.1 3.5 1 1 3 4 4 4 2 Nup133 N terminal like Nbas_N PF15492.1 AEO69533.1 - 0.081 12.0 0.0 7.6 5.5 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 AEO69533.1 - 0.11 11.9 1.0 22 4.4 0.2 3.0 2 1 1 3 3 3 0 PQQ-like domain IKI3 PF04762.7 AEO69533.1 - 0.24 9.1 0.0 0.37 8.5 0.0 1.2 1 0 0 1 1 1 0 IKI3 family PAT1 PF09770.4 AEO69533.1 - 5.1 5.2 43.4 7.8 4.5 30.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3829 PF12889.2 AEO69534.1 - 0.016 14.4 0.0 0.018 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Acyl-CoA_dh_1 PF00441.19 AEO69534.1 - 0.029 14.4 1.7 0.039 14.0 1.2 1.1 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain GLTSCR1 PF15249.1 AEO69534.1 - 0.12 12.5 0.5 0.17 12.0 0.4 1.2 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region DUF2347 PF09804.4 AEO69535.1 - 9.4e-107 356.4 0.0 1.3e-106 356.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 AEO69535.1 - 2e-47 161.5 0.0 1.3e-46 158.9 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 AEO69535.1 - 4e-06 26.5 0.0 7.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis NOA36 PF06524.7 AEO69535.1 - 1.7 7.8 5.0 2.7 7.1 3.5 1.2 1 0 0 1 1 1 0 NOA36 protein Acyltransferase PF01553.16 AEO69536.1 - 1.3e-32 111.9 0.0 1.9e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase GARS_A PF01071.14 AEO69537.1 - 1.3e-82 276.0 0.0 1.9e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 AEO69537.1 - 1.1e-34 118.8 0.0 3.2e-34 117.3 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 AEO69537.1 - 4.2e-33 114.5 0.0 8.8e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 AEO69537.1 - 9.2e-27 93.0 0.1 3e-26 91.4 0.0 2.0 2 0 0 2 2 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 AEO69537.1 - 3.4e-15 56.0 3.4 6e-15 55.2 1.5 2.1 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 AEO69537.1 - 6.4e-11 42.3 0.0 2.5e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AEO69537.1 - 1.3e-09 37.2 0.0 6.3e-09 35.0 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AEO69537.1 - 3.9e-05 23.0 0.0 6.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AEO69537.1 - 7.2e-05 22.1 0.0 0.00017 20.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 AEO69537.1 - 0.032 14.0 0.1 0.082 12.7 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain ATP-grasp_2 PF08442.5 AEO69537.1 - 0.088 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Pkinase PF00069.20 AEO69540.1 - 3e-28 98.6 0.0 5.4e-28 97.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO69540.1 - 3.3e-09 36.1 0.0 4e-08 32.6 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 AEO69540.1 - 0.013 15.2 2.6 0.12 12.0 1.8 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Esterase PF00756.15 AEO69542.1 - 4.6e-49 167.1 0.0 5.4e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 AEO69542.1 - 3e-07 30.2 0.0 4.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO69542.1 - 0.00019 21.3 0.0 0.0003 20.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO69542.1 - 0.00087 18.5 0.1 0.0016 17.7 0.1 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 AEO69542.1 - 0.019 13.8 0.0 0.082 11.7 0.0 1.9 1 1 0 1 1 1 0 Chlorophyllase enzyme Esterase_phd PF10503.4 AEO69542.1 - 0.024 13.9 0.7 0.067 12.4 0.5 1.8 1 1 0 1 1 1 0 Esterase PHB depolymerase PGAP1 PF07819.8 AEO69542.1 - 0.047 13.2 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase PF07224.6 AEO69542.1 - 0.13 11.0 0.0 2.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase DLH PF01738.13 AEO69542.1 - 0.28 10.4 1.7 4.8 6.4 1.2 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family Afi1 PF07792.7 AEO69543.1 - 8.3e-65 217.2 0.0 1.4e-64 216.4 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 AEO69543.1 - 6.6e-38 128.9 0.0 1.3e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 AEO69543.1 - 2.2e-08 33.0 0.2 0.02 13.4 0.0 3.9 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.4 AEO69543.1 - 0.0029 16.9 0.0 0.015 14.5 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) EF-hand_6 PF13405.1 AEO69546.1 - 2.6e-13 48.6 0.1 1.5e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 AEO69546.1 - 6.9e-11 40.6 2.1 0.00011 21.2 0.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 AEO69546.1 - 2.6e-09 37.0 0.0 0.00059 19.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 AEO69546.1 - 2.9e-08 32.6 3.2 0.00073 18.7 0.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 AEO69546.1 - 2e-05 24.0 0.3 0.17 11.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 AEO69546.1 - 0.00033 20.5 0.0 0.26 11.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain DUF566 PF04484.7 AEO69546.1 - 0.59 9.5 7.7 0.9 8.9 5.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Sec63 PF02889.11 AEO69547.1 - 1.5e-46 159.0 0.0 1.2e-45 156.1 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 AEO69547.1 - 2.4e-20 71.9 0.4 5.3e-20 70.9 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain VWA_CoxE PF05762.9 AEO69547.1 - 0.058 12.5 0.0 2 7.4 0.0 2.5 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein KTI12 PF08433.5 AEO69548.1 - 2.2e-65 220.5 0.0 4e-65 219.7 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 AEO69548.1 - 1.7e-05 25.6 1.0 4e-05 24.4 0.7 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AEO69548.1 - 0.00036 20.4 0.2 0.00096 19.0 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO69548.1 - 0.0056 16.9 3.4 0.018 15.3 1.5 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AEO69548.1 - 0.055 13.3 0.0 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AEO69548.1 - 0.097 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 AEO69548.1 - 0.11 12.2 0.2 0.99 9.2 0.0 2.5 3 0 0 3 3 3 0 Part of AAA domain 6PF2K PF01591.13 AEO69548.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Fe-S_biosyn PF01521.15 AEO69549.1 - 5.1e-11 42.5 0.0 9.3e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis Ribosomal_L30_N PF08079.7 AEO69550.1 - 7.7e-27 93.1 19.9 1.2e-26 92.5 13.8 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 AEO69550.1 - 3.8e-20 71.1 3.1 4.5e-20 70.9 0.8 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_S11 PF00411.14 AEO69551.1 - 1.1e-40 138.2 0.4 1.3e-40 137.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 AEO69551.1 - 0.029 13.2 0.0 0.037 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) eIF-3c_N PF05470.7 AEO69552.1 - 7.5e-176 585.7 22.2 7.5e-176 585.7 15.4 3.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 AEO69552.1 - 1.3e-14 54.3 0.2 1.7e-13 50.7 0.0 2.7 2 0 0 2 2 2 1 PCI domain DUF4051 PF13260.1 AEO69552.1 - 0.13 11.5 0.2 0.37 10.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) PROCN PF08083.6 AEO69553.1 - 5.8e-221 733.1 9.3 9.6e-221 732.4 6.4 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 AEO69553.1 - 7.8e-126 418.0 1.8 1.4e-125 417.1 1.2 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 AEO69553.1 - 5.6e-94 311.8 1.1 1.4e-93 310.5 0.8 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 AEO69553.1 - 1.1e-76 255.6 4.4 1.3e-76 255.4 1.8 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 AEO69553.1 - 6e-67 223.4 0.1 1.3e-66 222.3 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 AEO69553.1 - 2.5e-44 149.9 0.3 6.5e-44 148.6 0.0 1.9 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 AEO69553.1 - 8.5e-44 147.3 0.1 2.2e-43 146.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 DUF3753 PF12575.3 AEO69553.1 - 0.1 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Myb_DNA-bind_6 PF13921.1 AEO69554.1 - 3e-09 36.8 0.1 4.5e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO69554.1 - 3.5e-05 23.7 0.0 0.0001 22.2 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain SNF2_N PF00176.18 AEO69555.1 - 7.6e-70 235.0 0.0 1.1e-69 234.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO69555.1 - 3.7e-16 58.7 0.0 8.9e-16 57.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 AEO69555.1 - 6.2e-05 21.9 0.0 0.00022 20.1 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 AEO69555.1 - 0.0013 18.6 0.0 0.0041 16.9 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AEO69555.1 - 0.082 12.3 0.0 0.44 10.0 0.0 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase APG6 PF04111.7 AEO69555.1 - 3 6.8 9.0 5.9 5.8 6.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Hemerythrin PF01814.18 AEO69556.1 - 2e-10 40.9 7.3 5.5e-06 26.5 0.2 2.1 2 0 0 2 2 2 2 Hemerythrin HHE cation binding domain Mpv17_PMP22 PF04117.7 AEO69558.1 - 2.2e-12 46.3 2.9 2.1e-11 43.2 1.8 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family Serinc PF03348.10 AEO69558.1 - 0.047 12.4 2.7 0.064 11.9 1.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) EAP30 PF04157.11 AEO69559.1 - 8.9e-65 217.9 0.0 1.1e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family AAR2 PF05282.6 AEO69560.1 - 1.4e-42 145.9 0.0 2.8e-25 89.0 0.0 2.5 2 1 0 2 2 2 2 AAR2 protein DUF4604 PF15377.1 AEO69560.1 - 0.48 10.6 3.0 12 6.1 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) DUF3306 PF11748.3 AEO69561.1 - 0.18 12.4 7.2 0.49 11.0 5.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DEAD PF00270.24 AEO69563.1 - 4.4e-46 156.4 0.0 1e-44 152.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO69563.1 - 1.4e-28 98.5 0.0 2.9e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO69563.1 - 2.5e-05 24.1 0.0 0.00012 21.9 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2443 PF10398.4 AEO69563.1 - 0.013 15.3 0.1 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) DUF1253 PF06862.7 AEO69563.1 - 0.019 13.3 0.0 0.68 8.2 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 AEO69563.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain Glyoxalase_3 PF13468.1 AEO69563.1 - 0.052 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase-like domain Phos_pyr_kin PF08543.7 AEO69564.1 - 2.7e-79 265.8 0.5 1.3e-77 260.3 0.3 2.2 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 AEO69564.1 - 4.5e-43 147.4 0.0 6.7e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 AEO69564.1 - 7.8e-06 25.2 0.0 6.2e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 AEO69564.1 - 0.026 13.6 2.4 0.74 8.9 0.1 2.6 3 0 0 3 3 3 0 Hydroxyethylthiazole kinase family CbiK PF06180.6 AEO69564.1 - 0.15 11.0 0.1 0.3 10.1 0.1 1.4 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) RICTOR_N PF14664.1 AEO69565.1 - 1.8e-139 464.4 4.1 7.8e-138 459.0 1.3 2.6 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 AEO69565.1 - 2e-91 305.0 0.1 2.4e-90 301.5 0.0 2.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 AEO69565.1 - 1e-42 144.6 0.0 3.6e-41 139.6 0.0 3.0 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 AEO69565.1 - 9.5e-28 95.9 0.8 2.8e-26 91.2 0.1 3.5 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 AEO69565.1 - 8.1e-14 51.1 7.4 2.6e-13 49.5 5.1 2.0 1 0 0 1 1 1 1 Hr1 repeat PsiA PF06952.6 AEO69565.1 - 0.12 11.4 0.0 0.12 11.4 0.0 2.5 2 0 0 2 2 2 0 PsiA protein Methyltrn_RNA_4 PF09936.4 AEO69565.1 - 0.38 10.2 0.0 0.38 10.2 0.0 2.2 3 0 0 3 3 3 0 SAM-dependent RNA methyltransferase Uricase PF01014.13 AEO69566.1 - 1.8e-83 277.5 0.4 9.7e-46 155.2 0.2 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 AEO69566.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Plasmid recombination enzyme Ribosomal_L13 PF00572.13 AEO69567.1 - 9.3e-38 129.1 0.0 1.3e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 HMA PF00403.21 AEO69568.1 - 1.7e-15 56.9 0.0 3.1e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 AEO69568.1 - 3.8e-11 43.3 0.0 6.4e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TPR_11 PF13414.1 AEO69569.1 - 3e-21 74.8 11.1 5.8e-11 41.8 0.1 3.3 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 AEO69569.1 - 1.2e-17 62.7 10.2 5.1e-08 32.1 0.0 4.7 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 AEO69569.1 - 9.3e-16 56.4 5.1 1.3e-05 24.7 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 AEO69569.1 - 1.4e-12 47.3 1.1 2e-07 30.8 0.1 3.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 AEO69569.1 - 1.4e-12 46.4 3.9 2.8e-05 23.5 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 AEO69569.1 - 1.6e-08 34.4 2.0 0.068 13.6 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 AEO69569.1 - 5.8e-07 29.2 1.5 0.0027 17.7 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat PB1 PF00564.19 AEO69569.1 - 8.3e-07 28.5 0.1 1.6e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 PB1 domain TPR_7 PF13176.1 AEO69569.1 - 3.2e-06 26.4 0.4 0.00041 19.9 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 AEO69569.1 - 5.3e-06 26.9 1.2 0.0014 19.2 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 AEO69569.1 - 8.9e-06 25.4 0.4 0.044 13.6 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 AEO69569.1 - 0.00027 21.3 0.1 0.076 13.6 0.0 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 AEO69569.1 - 0.0014 18.7 1.3 0.027 14.6 0.1 2.6 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 AEO69569.1 - 0.013 15.8 0.2 0.085 13.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3808 PF10300.4 AEO69569.1 - 0.045 12.3 0.1 0.09 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) MIT PF04212.13 AEO69569.1 - 0.057 13.3 0.4 0.35 10.7 0.0 2.6 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Ribosomal_S21 PF01165.15 AEO69569.1 - 0.13 11.7 1.2 0.66 9.4 0.0 2.9 4 0 0 4 4 3 0 Ribosomal protein S21 PBP1_TM PF14812.1 AEO69569.1 - 2.1 8.7 13.4 0.66 10.3 0.4 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAR1 PF03101.10 AEO69570.1 - 4.9e-05 23.7 0.7 0.00012 22.5 0.5 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain HSBP1 PF06825.7 AEO69570.1 - 0.029 13.9 0.1 0.061 12.9 0.1 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 AEO69570.1 - 0.042 13.2 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin AFT PF08731.6 AEO69570.1 - 0.065 13.4 0.3 0.065 13.4 0.2 2.1 2 0 0 2 2 2 0 Transcription factor AFT FliD_N PF02465.13 AEO69571.1 - 0.026 14.8 0.2 0.87 9.9 0.1 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4254 PF14063.1 AEO69571.1 - 0.069 12.7 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) BLOC1_2 PF10046.4 AEO69571.1 - 0.14 12.3 0.2 4.3 7.5 0.1 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribosomal_L34e PF01199.13 AEO69572.1 - 4.2e-37 126.2 2.3 5.7e-37 125.8 1.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.3 AEO69572.1 - 0.21 11.2 3.7 2.5 7.8 0.2 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain DUF498 PF04430.9 AEO69573.1 - 4.9e-28 96.8 0.0 3.8e-27 94.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) CMAS PF02353.15 AEO69574.1 - 2.4e-61 207.2 0.0 3e-61 206.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 AEO69574.1 - 1.1e-13 51.2 0.0 2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO69574.1 - 5.4e-09 36.4 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO69574.1 - 0.00035 21.1 0.0 0.002 18.6 0.1 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO69574.1 - 0.00086 19.3 0.0 0.0021 18.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO69574.1 - 0.00095 19.5 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO69574.1 - 0.001 19.3 0.0 0.003 17.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO69574.1 - 0.0035 16.9 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AEO69574.1 - 0.022 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 AEO69574.1 - 0.034 13.4 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.9 AEO69574.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 AEO69574.1 - 0.2 11.3 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Alpha-amylase PF00128.19 AEO69575.1 - 1.9e-94 316.6 0.0 2.8e-94 316.0 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Cellulase PF00150.13 AEO69575.1 - 0.024 13.8 0.1 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) hDGE_amylase PF14701.1 AEO69575.1 - 0.086 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme G-patch_2 PF12656.2 AEO69576.1 - 2.6e-15 56.0 0.1 2.6e-15 56.0 0.1 2.5 3 0 0 3 3 3 1 DExH-box splicing factor binding site HSA PF07529.8 AEO69577.1 - 2e-17 62.7 0.4 2e-17 62.7 0.2 4.2 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 AEO69577.1 - 1.5e-13 50.5 0.1 4.7e-13 49.0 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO69577.1 - 0.0023 17.9 0.2 0.0052 16.8 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.27 AEO69578.1 - 3.4e-15 55.2 0.0 0.00059 19.6 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat INSIG PF07281.7 AEO69579.1 - 1.2e-51 174.8 0.5 1.8e-51 174.2 0.3 1.3 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) DUF2267 PF10025.4 AEO69580.1 - 0.12 12.4 1.2 0.21 11.6 0.6 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) efThoc1 PF11957.3 AEO69581.1 - 4.5e-164 546.5 1.1 5.7e-164 546.2 0.8 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 AEO69581.1 - 1.1e-20 73.8 0.0 2.1e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase PaO PF08417.7 AEO69581.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Pheophorbide a oxygenase AAA_11 PF13086.1 AEO69582.1 - 1.9e-24 86.5 0.0 5.2e-24 85.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.1 AEO69582.1 - 9.4e-13 47.9 0.0 1.6e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO69582.1 - 2e-09 37.0 0.1 6.7e-08 32.1 0.0 3.0 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 AEO69582.1 - 1.3e-07 31.4 0.0 0.0014 18.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 AEO69582.1 - 2.4e-05 24.2 0.0 4.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 AEO69582.1 - 0.0016 17.8 0.0 0.0041 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 AEO69582.1 - 0.0016 17.9 0.0 0.0072 15.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA PF00004.24 AEO69582.1 - 0.0019 18.3 0.0 0.0053 16.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO69582.1 - 0.0056 16.8 0.0 0.024 14.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO69582.1 - 0.013 15.5 0.5 0.062 13.2 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 AEO69582.1 - 0.016 14.3 0.0 0.039 13.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 AEO69582.1 - 0.024 15.4 0.0 0.8 10.5 0.0 3.2 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 AEO69582.1 - 0.034 13.1 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 AEO69582.1 - 0.063 12.1 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NB-ARC PF00931.17 AEO69582.1 - 0.071 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Adeno_IVa2 PF02456.10 AEO69582.1 - 0.086 11.4 0.1 0.14 10.7 0.1 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Arch_ATPase PF01637.13 AEO69582.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase RecA PF00154.16 AEO69582.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein UvrD-helicase PF00580.16 AEO69582.1 - 0.13 11.5 0.0 0.35 10.1 0.0 1.7 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain RNA_helicase PF00910.17 AEO69582.1 - 0.14 12.3 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 AEO69582.1 - 0.17 10.7 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MIF4G PF02854.14 AEO69583.1 - 7.7e-52 175.7 0.0 1.2e-51 175.1 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 AEO69583.1 - 2.9e-20 71.9 0.4 8.5e-20 70.4 0.3 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Eno-Rase_FAD_bd PF07055.7 AEO69583.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain DNA_pol_B PF00136.16 AEO69584.1 - 3.1e-109 365.8 0.2 4.7e-109 365.2 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 AEO69584.1 - 2.1e-61 206.5 0.0 4e-61 205.6 0.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 AEO69584.1 - 1.5e-41 142.3 0.0 2.6e-41 141.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 AEO69584.1 - 4.4e-24 84.0 9.5 4.4e-24 84.0 6.6 3.1 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal PPR_2 PF13041.1 AEO69585.1 - 8.4e-27 92.9 0.3 6.9e-16 57.9 0.0 5.4 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.1 AEO69585.1 - 4.3e-10 39.0 2.8 0.0018 18.4 0.0 5.6 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 AEO69585.1 - 1.7e-06 27.3 0.2 0.017 14.5 0.0 4.1 4 0 0 4 4 4 2 PPR repeat PPR PF01535.15 AEO69585.1 - 7.2e-06 25.6 3.7 0.0012 18.7 0.0 5.0 5 1 0 5 5 5 1 PPR repeat RRM_1 PF00076.17 AEO69588.1 - 0.0001 21.8 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO69588.1 - 0.00012 21.8 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO69588.1 - 0.0036 17.2 0.0 0.006 16.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 AEO69588.1 - 0.045 13.8 0.1 0.045 13.8 0.1 1.7 2 0 0 2 2 2 0 CASC3/Barentsz eIF4AIII binding Pkinase PF00069.20 AEO69589.1 - 5.5e-53 179.7 0.0 1.1e-52 178.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO69589.1 - 1.5e-23 83.1 0.0 3.1e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO69589.1 - 0.00053 19.8 0.1 0.00053 19.8 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 AEO69589.1 - 0.0035 16.7 0.2 0.011 15.1 0.1 1.6 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 AEO69589.1 - 0.047 13.7 0.1 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4430) RRM_1 PF00076.17 AEO69590.1 - 2.3e-61 203.3 0.0 3.7e-21 74.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO69590.1 - 4.9e-44 148.1 0.0 3.5e-15 55.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO69590.1 - 2.5e-31 107.2 0.0 1.6e-10 40.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO69590.1 - 1.3e-05 24.8 0.0 0.063 13.0 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 AEO69590.1 - 0.0045 16.9 0.0 4.1 7.4 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_3 PF08777.6 AEO69590.1 - 0.048 13.5 0.0 2.8 7.8 0.0 2.5 3 0 0 3 3 3 0 RNA binding motif Limkain-b1 PF11608.3 AEO69590.1 - 0.15 11.8 0.0 9.6 6.0 0.0 3.0 3 0 0 3 3 3 0 Limkain b1 TFIIA PF03153.8 AEO69592.1 - 0.0021 18.0 12.5 0.0028 17.6 8.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med2 PF11214.3 AEO69592.1 - 0.079 13.0 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 2 Cellulase PF00150.13 AEO69593.1 - 8.8e-22 77.6 0.1 2.1e-20 73.0 0.1 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TMEM220 PF15071.1 AEO69593.1 - 0.12 12.8 2.6 1.5 9.3 0.5 2.5 2 0 0 2 2 2 0 Transmembrane family 220, helix PH PF00169.24 AEO69594.1 - 3.2e-27 94.7 3.0 4.6e-17 62.1 0.5 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 AEO69594.1 - 8.2e-11 42.1 6.3 8.9e-06 25.9 0.2 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 AEO69594.1 - 1.7e-10 41.0 3.2 8.7e-07 29.1 0.7 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 AEO69594.1 - 0.0003 20.7 0.2 0.0006 19.8 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 AEO69594.1 - 0.0013 18.5 0.7 0.0052 16.6 0.3 2.0 2 0 0 2 2 2 1 PH domain Rota_VP2 PF05087.7 AEO69594.1 - 0.18 9.6 0.3 0.24 9.2 0.2 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein APH PF01636.18 AEO69595.1 - 4.6e-10 39.6 0.0 6.5e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 AEO69595.1 - 0.0032 16.6 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 AEO69595.1 - 0.0048 16.4 0.0 0.01 15.4 0.0 1.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 AEO69595.1 - 0.05 12.5 0.0 0.092 11.7 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase PLDc_N PF13396.1 AEO69596.1 - 0.34 10.6 7.7 1.2 8.8 5.3 1.9 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal DUF2392 PF10288.4 AEO69597.1 - 6.1e-16 58.6 0.0 4.8e-12 46.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 AEO69597.1 - 0.00014 21.4 0.0 0.04 13.4 0.0 2.3 2 0 0 2 2 2 2 PP-loop family Chorion_2 PF03964.10 AEO69597.1 - 0.026 15.0 0.8 0.026 15.0 0.6 2.4 3 0 0 3 3 3 0 Chorion family 2 SR-25 PF10500.4 AEO69597.1 - 5.4 6.4 11.9 8.5 5.7 8.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mito_carr PF00153.22 AEO69598.1 - 2.1e-60 200.4 1.4 5.3e-21 74.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 AEO69599.1 - 1.1e-16 59.9 1.9 1.4e-07 31.1 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat SRP9-21 PF05486.7 AEO69600.1 - 1.3e-23 82.4 6.0 1.3e-23 82.4 4.2 1.8 2 1 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) Suf PF05843.9 AEO69600.1 - 0.15 11.7 4.0 0.17 11.5 2.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 AEO69600.1 - 0.27 10.5 4.1 0.35 10.1 2.8 1.2 1 0 0 1 1 1 0 Spt20 family RR_TM4-6 PF06459.7 AEO69600.1 - 0.39 10.5 3.6 0.56 10.0 2.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PBP_sp32 PF07222.7 AEO69600.1 - 4 6.5 8.7 6 5.9 6.1 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Ribonuc_red_sm PF00268.16 AEO69601.1 - 4e-121 403.3 1.1 4.8e-121 403.0 0.8 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4112 PF13430.1 AEO69602.1 - 1.2e-34 118.4 0.1 1.6e-34 117.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF3099 PF11298.3 AEO69602.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) NUDIX PF00293.23 AEO69603.1 - 8.4e-15 54.5 0.0 1.9e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.8 AEO69603.1 - 2.3e-05 24.2 0.2 4.3e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Dcp2, box A domain TPR_20 PF14561.1 AEO69603.1 - 0.042 13.9 0.3 14 5.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SPO11_like PF03533.9 AEO69603.1 - 0.09 12.6 5.8 3.3 7.6 0.4 3.2 3 0 0 3 3 3 0 SPO11 homologue RRM_6 PF14259.1 AEO69604.1 - 0.019 14.9 0.2 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 AEO69606.1 - 1.5e-60 204.5 0.0 2.4e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO69606.1 - 5.1e-29 101.1 0.0 8.5e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO69606.1 - 0.00032 19.7 0.0 0.00052 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AEO69606.1 - 0.002 17.2 0.0 0.0036 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO69606.1 - 0.014 15.1 7.5 0.069 12.8 0.0 3.1 3 1 1 4 4 4 0 Phosphotransferase enzyme family DUF3987 PF13148.1 AEO69606.1 - 4.2 5.8 8.7 6.2 5.2 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4554 PF15091.1 AEO69606.1 - 5.2 5.6 6.2 7.2 5.2 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) PGBA_C PF15437.1 AEO69606.1 - 6.7 6.9 21.3 0.44 10.7 11.0 1.8 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal Rtf2 PF04641.7 AEO69606.1 - 9.7 5.2 10.6 17 4.4 7.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1900 PF08954.6 AEO69607.1 - 1.3e-49 167.2 0.0 6.2e-49 165.0 0.0 2.1 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 AEO69607.1 - 6.4e-35 118.6 0.0 1.2e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 AEO69607.1 - 2.4e-24 84.2 3.4 3.6e-07 29.8 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 AEO69607.1 - 0.0014 16.8 0.4 0.071 11.2 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 AEO69607.1 - 0.0057 16.3 0.0 0.052 13.2 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A HemX PF04375.9 AEO69607.1 - 0.038 12.5 11.1 0.054 12.0 7.7 1.2 1 0 0 1 1 1 0 HemX SlyX PF04102.7 AEO69607.1 - 1.4 9.3 10.5 1 9.7 5.0 2.2 2 0 0 2 2 2 0 SlyX Glyco_transf_22 PF03901.12 AEO69608.1 - 3.5e-72 243.7 16.1 4.8e-72 243.2 11.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family LigD_N PF13298.1 AEO69608.1 - 0.18 11.9 0.1 0.32 11.1 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) Aminotran_3 PF00202.16 AEO69609.1 - 5e-105 351.1 0.0 6e-105 350.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 AEO69609.1 - 0.00037 19.7 0.0 0.00073 18.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 AEO69609.1 - 0.035 13.0 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II RVT_1 PF00078.22 AEO69612.1 - 0.02 14.2 0.1 0.02 14.2 0.1 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1996 PF09362.5 AEO69613.1 - 4.1e-89 298.2 0.7 5.7e-89 297.8 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Mastoparan PF08249.6 AEO69613.1 - 0.54 10.9 2.2 1.1 9.9 1.5 1.5 1 0 0 1 1 1 0 Mastoparan protein DUF3543 PF12063.3 AEO69614.1 - 6.4e-95 316.8 0.4 6.4e-95 316.8 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 AEO69614.1 - 1.8e-60 204.3 0.0 3.7e-60 203.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO69614.1 - 3.7e-40 137.6 0.0 8.7e-40 136.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO69614.1 - 0.0094 15.7 0.1 0.1 12.3 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 AEO69614.1 - 0.26 10.0 0.0 0.37 9.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SRP-alpha_N PF04086.8 AEO69615.1 - 9.6 5.4 16.5 17 4.6 11.0 1.6 1 1 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Zeta_toxin PF06414.7 AEO69616.1 - 2.6e-31 108.3 0.3 2.4e-11 43.1 0.1 3.2 3 0 0 3 3 3 3 Zeta toxin AAA_16 PF13191.1 AEO69616.1 - 0.055 13.4 1.3 0.26 11.2 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain Sigma54_activat PF00158.21 AEO69616.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF87 PF01935.12 AEO69616.1 - 0.14 11.9 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 MFS_1 PF07690.11 AEO69617.1 - 5.5e-34 117.4 29.2 8.1e-34 116.8 19.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily SPC25 PF06703.6 AEO69617.1 - 8.5 5.9 7.2 0.43 10.1 0.5 2.2 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) RhoGAP PF00620.22 AEO69618.1 - 1.5e-38 131.8 0.0 2.5e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF290 PF01060.18 AEO69618.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Transthyretin-like family zf-Tim10_DDP PF02953.10 AEO69619.1 - 8.1e-20 69.8 0.5 1.1e-19 69.4 0.3 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 AEO69619.1 - 0.03 13.7 1.1 0.22 10.9 0.5 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) HATPase_c_5 PF14501.1 AEO69619.1 - 0.039 13.6 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 GHKL domain Thionin PF00321.12 AEO69619.1 - 0.078 13.2 0.9 0.12 12.6 0.6 1.3 1 0 0 1 1 1 0 Plant thionin Nup188 PF10487.4 AEO69620.1 - 1.7e-27 95.8 0.0 4.4e-21 74.6 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.16 AEO69621.1 - 1.6e-99 332.0 0.0 2.6e-99 331.4 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 AEO69621.1 - 7.9e-51 172.2 0.0 1.3e-50 171.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.17 AEO69621.1 - 2.4e-46 157.7 0.0 2.1e-43 148.1 0.0 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 AEO69621.1 - 4.4e-05 23.0 0.1 0.00013 21.4 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 AEO69621.1 - 0.0033 16.9 0.1 0.015 14.7 0.0 2.1 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain Use1 PF09753.4 AEO69623.1 - 3.9e-07 29.7 3.4 1.3e-06 28.0 2.3 1.8 1 1 0 1 1 1 1 Membrane fusion protein Use1 Snapin_Pallidin PF14712.1 AEO69623.1 - 0.019 15.2 0.6 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin Hid1 PF12722.2 AEO69623.1 - 0.79 7.3 5.1 1.1 6.8 3.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_BLLF1 PF05109.8 AEO69623.1 - 2.7 5.8 34.5 3.3 5.5 23.9 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF572 PF04502.8 AEO69623.1 - 6 5.9 9.2 2.7 7.1 4.9 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF572) Methyltransf_28 PF02636.12 AEO69624.1 - 4.6e-80 268.6 0.0 5.6e-80 268.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Lung_7-TM_R PF06814.8 AEO69625.1 - 2.2e-56 190.9 11.0 9.7e-46 156.0 7.3 2.1 1 1 1 2 2 2 2 Lung seven transmembrane receptor DUF1673 PF07895.6 AEO69625.1 - 0.098 12.1 3.5 0.2 11.1 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF4131 PF13567.1 AEO69625.1 - 0.22 10.8 9.0 0.018 14.4 1.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) GpcrRhopsn4 PF10192.4 AEO69625.1 - 0.58 9.2 9.5 1.3 8.1 6.6 1.5 1 1 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain PrgI PF12666.2 AEO69625.1 - 1.3 9.2 13.4 0.12 12.5 1.7 2.9 1 1 2 3 3 3 0 PrgI family protein DUF1980 PF09323.5 AEO69625.1 - 6.9 6.3 6.8 0.69 9.6 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Pro_isomerase PF00160.16 AEO69626.1 - 1.1e-44 152.4 0.0 1.8e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 AEO69626.1 - 8.4e-06 25.6 0.0 3.6e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 U-box domain Fungal_trans_2 PF11951.3 AEO69628.1 - 1.4e-10 40.3 0.0 7.9e-09 34.5 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO69628.1 - 6.1e-08 32.4 9.0 1.2e-07 31.5 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.4 AEO69628.1 - 0.068 11.4 5.2 0.093 11.0 3.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Pol_alpha_B_N PF08418.5 AEO69628.1 - 4.5 6.7 11.6 1.7 8.1 4.2 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Ricin_B_lectin PF00652.17 AEO69629.1 - 1.2e-15 57.6 3.4 1.4e-07 31.5 1.1 3.8 2 2 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 AEO69629.1 - 0.022 15.1 0.6 19 5.7 0.0 3.9 3 2 1 4 4 4 0 Ricin-type beta-trefoil lectin domain-like Ribosomal_S19e PF01090.14 AEO69630.1 - 4.6e-58 194.6 0.7 5.3e-58 194.4 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Prim-Pol PF09250.6 AEO69630.1 - 0.039 13.9 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Ank_5 PF13857.1 AEO69631.1 - 3.2e-10 39.9 0.0 2.3e-09 37.2 0.0 2.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 AEO69631.1 - 4.5e-10 38.8 0.0 8.8e-07 28.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 AEO69631.1 - 2.5e-09 37.3 0.0 3.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AEO69631.1 - 2.4e-08 34.2 0.0 4.9e-05 23.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO69631.1 - 0.0005 20.0 0.0 0.022 14.9 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat SSP160 PF06933.6 AEO69632.1 - 9.9 4.0 7.3 11 3.8 5.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Zip PF02535.17 AEO69633.1 - 7.9e-53 179.5 4.6 9.3e-53 179.2 3.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF3722 PF12519.3 AEO69634.1 - 2.3e-86 289.2 0.0 2.9e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 AEO69634.1 - 3.2e-05 23.3 0.0 0.0016 17.7 0.1 2.3 2 0 0 2 2 2 2 Eukaryotic porin Scytalone_dh PF02982.9 AEO69635.1 - 9.2e-88 291.8 0.5 1e-87 291.6 0.4 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 AEO69635.1 - 2.1e-06 27.6 0.1 3e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF2293 PF10056.4 AEO69636.1 - 8.1e-33 112.2 1.5 1.9e-32 111.0 1.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) FMO-like PF00743.14 AEO69637.1 - 1.3e-37 129.2 0.0 4.5e-18 64.7 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 AEO69637.1 - 6.1e-20 72.1 0.0 1.7e-12 47.8 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO69637.1 - 5.1e-10 39.2 0.3 6.4e-09 35.7 0.0 2.6 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO69637.1 - 1.2e-09 37.6 9.5 5.7e-08 32.0 2.4 3.5 3 2 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 AEO69637.1 - 3.3e-09 36.7 3.4 8.5e-06 25.6 0.1 3.9 4 0 0 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 AEO69637.1 - 1.2e-08 34.3 1.0 1.6e-05 24.0 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 AEO69637.1 - 1.9e-07 31.1 0.0 0.012 15.4 0.5 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO69637.1 - 6.6e-07 28.7 0.0 2.2e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 AEO69637.1 - 1.8e-05 23.9 0.4 5.5e-05 22.3 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.19 AEO69637.1 - 4.3e-05 22.7 0.5 0.0024 17.0 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 AEO69637.1 - 0.00056 20.2 7.5 0.0013 19.1 0.2 3.2 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 AEO69637.1 - 0.00076 19.5 0.2 0.056 13.5 0.1 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 AEO69637.1 - 0.0012 17.3 0.8 0.0026 16.2 0.6 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 AEO69637.1 - 0.0026 16.8 0.4 0.0055 15.8 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 AEO69637.1 - 0.003 16.4 1.4 0.003 16.4 0.9 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 AEO69637.1 - 0.0049 15.7 2.3 0.0097 14.8 0.7 2.1 3 0 0 3 3 3 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 AEO69637.1 - 0.0077 15.8 0.8 0.017 14.8 0.5 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 AEO69637.1 - 0.011 14.4 1.5 0.32 9.5 0.8 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.1 AEO69637.1 - 0.016 15.4 0.0 0.82 9.9 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_2 PF03446.10 AEO69637.1 - 0.03 14.1 0.1 0.063 13.1 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 AEO69637.1 - 0.059 12.8 1.2 0.14 11.5 0.8 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 AEO69637.1 - 0.11 12.5 1.1 0.21 11.5 0.7 1.5 1 0 0 1 1 1 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 AEO69637.1 - 0.2 10.8 0.3 1.1 8.4 0.1 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 AEO69637.1 - 0.24 10.9 3.1 0.44 10.0 0.4 2.3 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain TauD PF02668.11 AEO69638.1 - 2.1e-56 191.5 0.3 2.8e-56 191.0 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SNF2_N PF00176.18 AEO69639.1 - 9.2e-34 116.5 0.1 4.3e-30 104.5 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO69639.1 - 4e-08 32.9 0.0 1.1e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 AEO69639.1 - 3.7e-07 29.6 8.6 7.5e-07 28.7 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AEO69639.1 - 2.7e-06 27.1 7.1 6.6e-06 25.8 4.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DEAD PF00270.24 AEO69639.1 - 2.2e-05 24.0 0.0 0.00017 21.1 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 AEO69639.1 - 2.7e-05 24.0 0.0 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.1 AEO69639.1 - 0.0011 18.8 9.1 0.0025 17.7 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO69639.1 - 0.012 15.3 13.6 0.025 14.3 9.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain TFIIA PF03153.8 AEO69639.1 - 0.71 9.7 8.4 1.1 9.1 5.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_UBOX PF13445.1 AEO69639.1 - 1 9.1 7.4 2.3 8.0 5.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Nop14 PF04147.7 AEO69639.1 - 1.1 7.1 10.4 1.6 6.5 7.2 1.2 1 0 0 1 1 1 0 Nop14-like family zf-RING_2 PF13639.1 AEO69639.1 - 2 8.2 12.5 5 7.0 8.7 1.7 1 0 0 1 1 1 0 Ring finger domain CorA PF01544.13 AEO69640.1 - 1.2e-27 96.6 3.3 2.8e-23 82.4 1.0 2.4 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Carb_bind PF10645.4 AEO69641.1 - 1.3e-27 95.3 8.1 2.5e-27 94.4 5.6 1.5 1 0 0 1 1 1 1 Carbohydrate binding IGFL PF14653.1 AEO69641.1 - 0.42 10.6 3.7 1.2 9.2 1.9 2.0 1 1 1 2 2 2 0 Insulin growth factor-like family PAPS_reduct PF01507.14 AEO69642.1 - 1.6e-26 93.1 0.0 3.6e-18 65.9 0.0 2.3 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family rve PF00665.21 AEO69643.1 - 0.034 14.2 0.0 0.048 13.7 0.0 1.4 1 1 0 1 1 1 0 Integrase core domain SNF2_N PF00176.18 AEO69644.1 - 5.2e-71 238.8 0.0 7.5e-71 238.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 AEO69644.1 - 1.6e-26 92.2 0.0 3.6e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 AEO69644.1 - 1e-12 47.7 0.0 2.6e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 AEO69644.1 - 1e-06 28.6 9.4 2.2e-06 27.6 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO69644.1 - 0.00011 21.7 9.9 0.00021 20.8 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO69644.1 - 0.0037 16.9 7.9 0.0075 15.9 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO69644.1 - 0.0044 16.8 9.9 0.011 15.5 6.9 1.7 1 0 0 1 1 1 1 Ring finger domain ResIII PF04851.10 AEO69644.1 - 0.0061 16.4 0.0 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.1 AEO69644.1 - 0.17 11.6 8.7 0.37 10.5 6.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain SQS_PSY PF00494.14 AEO69645.1 - 8.4e-57 192.4 0.2 1.2e-56 191.9 0.1 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase LDB19 PF13002.2 AEO69646.1 - 2e-36 125.2 0.1 3.8e-36 124.3 0.1 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 AEO69646.1 - 2.2e-05 24.3 0.0 5.6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain GTP_EFTU PF00009.22 AEO69647.1 - 5e-21 75.0 0.0 1.2e-20 73.7 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AEO69647.1 - 4.4e-15 55.6 0.0 1.2e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AEO69647.1 - 2.3e-10 40.4 0.9 2.7e-09 37.0 0.6 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AEO69647.1 - 0.00096 19.0 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AEO69647.1 - 0.0023 18.4 0.1 0.03 14.8 0.1 2.7 2 1 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 AEO69647.1 - 0.0024 17.3 0.7 0.32 10.4 0.1 3.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 AEO69647.1 - 0.036 13.2 0.1 0.07 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 AEO69647.1 - 0.064 13.0 0.1 0.19 11.5 0.1 1.8 2 0 0 2 2 2 0 Dynamin family LSM PF01423.17 AEO69648.1 - 1.9e-17 62.5 0.2 2.4e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain Staphostatin_B PF09023.5 AEO69648.1 - 0.12 12.1 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Staphostatin B ATP13 PF12921.2 AEO69649.1 - 2.2e-21 75.5 0.0 4.6e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_3 PF13812.1 AEO69649.1 - 0.011 15.9 4.5 0.33 11.3 0.0 4.7 7 0 0 7 7 7 0 Pentatricopeptide repeat domain PIG-L PF02585.12 AEO69650.1 - 9.8e-27 93.9 0.0 1.4e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF202 PF02656.10 AEO69651.1 - 0.28 11.4 1.6 1.4 9.2 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Polysacc_deac_1 PF01522.16 AEO69652.1 - 2.3e-31 107.9 0.0 3.3e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Abhydrolase_6 PF12697.2 AEO69653.1 - 3.6e-21 76.0 2.6 4.5e-21 75.7 1.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO69653.1 - 4e-07 29.8 0.2 1.5e-06 27.9 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO69653.1 - 5e-05 23.0 0.0 8.6e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family MOSC_N PF03476.11 AEO69654.1 - 1.1e-12 47.7 0.0 3.2e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 AEO69654.1 - 3.2e-12 46.0 0.0 6.9e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Fungal_trans PF04082.13 AEO69655.1 - 7.9e-20 70.8 0.0 1.2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 AEO69655.1 - 1.3e-08 34.7 12.6 0.00068 19.8 2.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO69655.1 - 1.3e-06 28.3 6.4 1.3e-06 28.3 4.4 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO69655.1 - 0.00011 22.3 14.0 0.061 13.6 1.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 AEO69655.1 - 0.083 13.1 1.2 0.2 11.9 0.8 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AEO69655.1 - 0.16 12.1 3.3 0.8 9.9 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AEO69655.1 - 2.7 8.0 8.1 0.67 9.9 0.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger FA_desaturase PF00487.19 AEO69656.1 - 7e-13 48.6 2.9 8e-13 48.4 2.0 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF2422 PF10337.4 AEO69657.1 - 7.2e-106 354.7 0.0 7.2e-106 354.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 AEO69657.1 - 1.9e-17 63.3 17.2 1.9e-17 63.3 11.9 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 AEO69657.1 - 5.7e-09 35.9 0.0 5e-05 23.0 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2421) Pterin_bind PF00809.17 AEO69657.1 - 0.06 12.7 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Pterin binding enzyme ALMT PF11744.3 AEO69657.1 - 0.18 10.4 6.6 0.29 9.7 3.8 1.8 2 0 0 2 2 2 0 Aluminium activated malate transporter AAA PF00004.24 AEO69658.1 - 5.1e-06 26.7 0.2 3e-05 24.2 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 AEO69658.1 - 0.0003 19.5 0.0 0.0029 16.3 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 AEO69658.1 - 0.0012 18.9 0.0 0.0039 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO69658.1 - 0.0073 17.1 0.0 0.023 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO69658.1 - 0.031 14.2 0.0 0.09 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 AEO69658.1 - 0.097 12.5 0.0 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AEO69658.1 - 0.26 11.4 0.0 1.3 9.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 AEO69658.1 - 0.29 10.8 0.0 0.66 9.6 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase TIP49 PF06068.8 AEO69658.1 - 0.33 9.6 0.0 0.58 8.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus PRP38_assoc PF12871.2 AEO69660.1 - 0.0046 17.4 40.3 0.0046 17.4 28.0 6.0 4 3 1 5 5 5 2 Pre-mRNA-splicing factor 38-associated hydrophilic C-term PTCB-BRCT PF12738.2 AEO69661.1 - 6.1e-33 112.4 0.1 9.8e-21 73.3 0.0 3.3 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.21 AEO69661.1 - 2.9e-28 97.8 0.6 1.7e-13 50.5 0.0 3.7 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain NUDIX PF00293.23 AEO69662.1 - 2.1e-14 53.3 1.2 4e-14 52.4 0.8 1.6 1 1 0 1 1 1 1 NUDIX domain ADH_zinc_N_2 PF13602.1 AEO69663.1 - 9.3e-23 81.5 0.0 2.4e-22 80.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 AEO69663.1 - 1.1e-18 67.0 0.3 1.7e-18 66.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 AEO69663.1 - 0.0096 15.3 0.1 0.013 14.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.16 AEO69663.1 - 0.033 13.7 0.7 0.055 13.0 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 AEO69663.1 - 0.04 13.9 1.4 0.074 13.0 1.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Semialdhyde_dh PF01118.19 AEO69663.1 - 0.074 13.3 0.2 0.13 12.5 0.2 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain E1-N PF14463.1 AEO69663.1 - 0.36 10.4 9.8 0.2 11.2 3.0 2.6 1 1 2 3 3 3 0 E1 N-terminal domain Asp PF00026.18 AEO69664.1 - 3.7e-58 197.2 0.1 4.6e-58 196.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO69664.1 - 2.1e-12 47.3 0.5 1.5e-10 41.2 0.0 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 AEO69664.1 - 0.0094 15.5 0.0 0.27 10.7 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal PapD_N PF00345.15 AEO69664.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Asp_protease_2 PF13650.1 AEO69664.1 - 2.3 8.7 5.7 8.2 7.0 0.0 3.3 3 1 0 3 3 3 0 Aspartyl protease Hemerythrin PF01814.18 AEO69665.1 - 1.3e-12 47.9 0.0 1.9e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Glyco_hydro_17 PF00332.13 AEO69666.1 - 4.5e-08 32.4 1.2 8.5e-08 31.5 0.4 1.7 1 1 0 2 2 2 1 Glycosyl hydrolases family 17 DUF4246 PF14033.1 AEO69667.1 - 6.1e-161 536.4 0.0 1.8e-132 442.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) ABC2_membrane PF01061.19 AEO69668.1 - 8.3e-87 289.7 50.8 3.2e-46 157.1 9.8 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 AEO69668.1 - 2e-37 128.5 0.0 2e-17 63.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 AEO69668.1 - 3.3e-34 116.6 0.2 6e-28 96.5 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 AEO69668.1 - 6e-20 71.1 0.3 1.8e-19 69.5 0.0 2.0 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 AEO69668.1 - 5.7e-10 38.9 0.1 3.3e-05 23.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 AEO69668.1 - 1.6e-08 34.0 39.7 2.4e-06 26.8 11.1 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 AEO69668.1 - 4.5e-05 23.3 0.5 0.0055 16.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 AEO69668.1 - 7.5e-05 22.1 1.9 0.0084 15.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 AEO69668.1 - 8.4e-05 21.8 0.1 0.001 18.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 AEO69668.1 - 0.00015 22.5 0.0 0.067 14.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 AEO69668.1 - 0.0067 15.8 0.3 0.0067 15.8 0.2 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 AEO69668.1 - 0.008 16.4 0.1 0.086 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 AEO69668.1 - 0.0087 15.3 0.0 11 5.1 0.0 3.7 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 AEO69668.1 - 0.013 15.2 2.0 1.2 8.7 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 AEO69668.1 - 0.017 15.0 4.7 0.1 12.5 0.1 3.0 3 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 AEO69668.1 - 0.018 15.2 0.1 0.51 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 AEO69668.1 - 0.022 15.2 0.1 3.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 AEO69668.1 - 0.023 14.6 0.1 0.055 13.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 AEO69668.1 - 0.034 14.1 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AEO69668.1 - 0.065 12.6 0.2 8.6 5.7 0.0 2.7 3 0 0 3 3 2 0 AAA-like domain MMR_HSR1 PF01926.18 AEO69668.1 - 0.079 12.9 0.0 17 5.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 AEO69668.1 - 0.079 13.2 0.1 0.66 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 AEO69668.1 - 0.084 13.0 0.1 7.6 6.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ADK PF00406.17 AEO69668.1 - 0.12 12.1 0.5 14 5.5 0.0 2.3 2 0 0 2 2 2 0 Adenylate kinase UPF0079 PF02367.12 AEO69668.1 - 0.31 10.6 2.5 0.67 9.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF87 PF01935.12 AEO69668.1 - 4.1 7.1 4.1 32 4.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 Methyltransf_11 PF08241.7 AEO69669.1 - 1.6e-14 54.1 0.0 2.5e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO69669.1 - 7.7e-14 51.9 0.0 1.2e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO69669.1 - 3.2e-13 50.2 0.0 6.4e-13 49.2 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO69669.1 - 7.3e-12 45.2 0.0 9.5e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO69669.1 - 1.2e-10 41.6 0.0 2.1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO69669.1 - 2.9e-10 39.9 0.0 3.7e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO69669.1 - 6e-10 39.1 0.0 8.6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AEO69669.1 - 2.1e-08 33.5 0.0 2.6e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 AEO69669.1 - 0.0015 17.6 0.0 0.0022 17.1 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 AEO69669.1 - 0.023 14.0 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TPMT PF05724.6 AEO69669.1 - 0.03 13.7 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) TehB PF03848.9 AEO69669.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.14 AEO69669.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BCS1_N PF08740.6 AEO69670.1 - 1.3e-39 135.7 0.9 1.3e-39 135.7 0.6 1.5 2 0 0 2 2 1 1 BCS1 N terminal AAA PF00004.24 AEO69670.1 - 7.7e-17 61.7 0.2 1.1e-15 57.9 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AEO69670.1 - 0.00012 22.8 2.2 0.001 19.8 1.5 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO69670.1 - 0.00077 19.4 1.2 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 AEO69670.1 - 0.00095 18.8 0.2 0.0029 17.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO69670.1 - 0.00096 18.8 0.0 0.004 16.8 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 AEO69670.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 AEO69670.1 - 0.0022 17.4 0.0 0.0057 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO69670.1 - 0.011 15.5 0.0 0.032 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 AEO69670.1 - 0.014 14.7 0.0 0.063 12.6 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.1 AEO69670.1 - 0.02 14.7 0.0 0.058 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AEO69670.1 - 0.035 14.2 0.2 0.19 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 AEO69670.1 - 0.087 11.9 0.9 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.1 AEO69670.1 - 0.11 12.8 0.1 0.11 12.8 0.1 2.4 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.8 AEO69670.1 - 0.11 11.2 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus eRF1_1 PF03463.10 AEO69671.1 - 3.8e-26 91.2 0.2 8.3e-26 90.1 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 AEO69671.1 - 2.5e-23 82.8 0.1 4.5e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 AEO69671.1 - 2.2e-19 69.7 0.0 5.1e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 WD40 PF00400.27 AEO69672.1 - 1.3e-31 107.2 7.6 4.2e-10 39.1 0.0 7.6 7 1 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 AEO69672.1 - 0.13 12.0 0.2 3.2 7.5 0.0 3.0 3 2 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.11 AEO69672.1 - 0.15 10.3 0.2 3.9 5.6 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain IKI3 PF04762.7 AEO69672.1 - 0.28 8.9 0.1 9.1 3.9 0.1 2.1 1 1 1 2 2 2 0 IKI3 family Thioredoxin PF00085.15 AEO69673.1 - 9.6e-23 79.8 0.0 1.3e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AEO69673.1 - 1.9e-08 34.2 0.0 6.1e-06 26.2 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 AEO69673.1 - 1.6e-06 28.2 0.1 2.4e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 AEO69673.1 - 2.7e-06 27.0 0.0 5e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AEO69673.1 - 4.8e-06 26.1 0.0 6.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 AEO69673.1 - 7.5e-05 22.6 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 AEO69673.1 - 0.016 14.7 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.1 AEO69673.1 - 0.035 13.9 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain HyaE PF07449.6 AEO69673.1 - 0.056 13.3 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Dimer_Tnp_hAT PF05699.9 AEO69674.1 - 0.05 13.2 0.1 0.053 13.1 0.1 1.0 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Amidoligase_2 PF12224.3 AEO69675.1 - 1.1e-14 54.7 0.0 2.4e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Putative amidoligase enzyme DUF2708 PF10917.3 AEO69675.1 - 0.09 12.5 1.1 0.17 11.6 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2708) PaO PF08417.7 AEO69675.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Pheophorbide a oxygenase MFS_1 PF07690.11 AEO69676.1 - 1e-36 126.4 30.9 2.1e-36 125.4 21.4 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO69676.1 - 6.6e-08 31.2 4.9 6.6e-08 31.2 3.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 AEO69676.1 - 2.3e-07 29.7 13.3 2.3e-07 29.7 9.2 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Folate_carrier PF01770.13 AEO69676.1 - 0.00066 18.3 0.1 0.0011 17.6 0.1 1.2 1 0 0 1 1 1 1 Reduced folate carrier ATG22 PF11700.3 AEO69676.1 - 1.8 6.9 22.2 0.11 10.9 10.0 2.2 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like MFS_1 PF07690.11 AEO69677.1 - 2.3e-30 105.5 29.5 2.3e-30 105.5 20.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO69677.1 - 1.4e-11 43.6 24.0 5.5e-11 41.7 16.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 AEO69677.1 - 1.6e-08 33.2 3.1 1.6e-08 33.2 2.2 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Mating_C PF12737.2 AEO69678.1 - 0.12 11.2 14.3 0.15 10.9 9.9 1.0 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Fungal_trans PF04082.13 AEO69679.1 - 1.1e-09 37.5 0.0 1.5e-06 27.3 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO69679.1 - 6e-06 26.0 9.8 1.4e-05 24.8 6.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 AEO69679.1 - 0.0013 18.9 1.7 0.0013 18.9 1.2 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AEO69679.1 - 0.01 15.9 0.9 0.01 15.9 0.6 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 AEO69679.1 - 0.011 15.9 9.4 0.15 12.5 1.1 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 AEO69679.1 - 0.026 14.3 2.7 0.067 12.9 1.9 1.8 1 0 0 1 1 1 0 BED zinc finger zf-C2HC_2 PF13913.1 AEO69679.1 - 0.14 11.8 3.3 0.33 10.6 2.3 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 AEO69679.1 - 5.1 7.6 19.6 0.055 13.8 3.2 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Oxidored_q6 PF01058.17 AEO69680.1 - 7.5e-23 80.5 0.0 8.2e-23 80.4 0.0 1.0 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Cutinase PF01083.17 AEO69681.1 - 1e-48 165.4 4.7 1.6e-48 164.8 3.3 1.3 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 AEO69681.1 - 0.0031 17.2 0.7 0.0048 16.6 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 AEO69681.1 - 0.011 15.1 0.3 0.016 14.6 0.2 1.3 1 0 0 1 1 1 0 PE-PPE domain VirJ PF06057.6 AEO69681.1 - 0.032 14.0 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF1524 PF07510.6 AEO69683.1 - 2.5e-12 46.8 0.0 3.1e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) F-box-like PF12937.2 AEO69684.1 - 5.9e-05 22.7 0.1 0.0002 20.9 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO69684.1 - 0.00018 21.0 0.3 0.00058 19.4 0.0 2.1 2 0 0 2 2 2 1 F-box domain WD40 PF00400.27 AEO69686.1 - 5.8e-23 79.8 11.8 7e-11 41.5 0.2 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 AEO69686.1 - 7.3e-18 64.2 0.0 1.6e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nucleoporin_N PF08801.6 AEO69686.1 - 0.022 13.5 0.6 0.33 9.6 0.2 2.5 1 1 1 2 2 2 0 Nup133 N terminal like O-FucT PF10250.4 AEO69687.1 - 6.6e-09 35.3 0.0 2.4e-07 30.2 0.0 2.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyoxalase_2 PF12681.2 AEO69688.1 - 2.8e-13 50.3 0.0 3.6e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AEO69688.1 - 0.00013 21.8 0.0 0.00022 21.1 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 AEO69688.1 - 0.0035 17.3 0.0 0.005 16.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Abhydrolase_6 PF12697.2 AEO69689.1 - 1.4e-29 103.5 1.0 1.7e-29 103.3 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO69689.1 - 3.3e-16 59.3 0.0 7.6e-16 58.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO69689.1 - 2.8e-13 49.9 0.0 4.4e-11 42.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 AEO69689.1 - 0.00021 21.0 0.0 0.00072 19.3 0.0 2.0 1 1 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 AEO69689.1 - 0.00063 19.6 0.1 0.0014 18.4 0.0 1.6 2 0 0 2 2 2 1 TAP-like protein Peptidase_S9 PF00326.16 AEO69689.1 - 0.0022 17.2 0.0 0.0073 15.5 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 AEO69689.1 - 0.089 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family EHN PF06441.7 AEO69689.1 - 0.12 12.3 0.1 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 Epoxide hydrolase N terminus FAD_binding_4 PF01565.18 AEO69693.1 - 4.8e-24 84.4 1.8 7.7e-24 83.7 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO69693.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_C1 PF00112.18 AEO69694.1 - 1.8e-28 99.9 2.5 1.8e-28 99.9 1.7 2.1 2 0 0 2 2 2 1 Papain family cysteine protease Acetyltransf_1 PF00583.19 AEO69695.1 - 2e-17 62.9 0.0 2.8e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AEO69695.1 - 2.1e-10 40.7 0.0 2.5e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AEO69695.1 - 4.2e-06 26.7 0.0 5e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO69695.1 - 1e-05 25.6 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AEO69695.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO69695.1 - 5.6e-05 22.8 0.0 9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 AEO69695.1 - 0.00019 21.6 0.0 0.00022 21.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 AEO69695.1 - 0.042 13.5 0.0 0.086 12.5 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.1 AEO69695.1 - 0.15 11.9 0.0 0.55 10.0 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DLH PF01738.13 AEO69696.1 - 1.1e-24 86.9 0.0 1.5e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AEO69696.1 - 2.4e-06 27.3 0.0 3.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_2 PF12796.2 AEO69697.1 - 4.1e-25 87.9 0.4 3e-12 46.7 0.3 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AEO69697.1 - 6.3e-22 76.2 5.2 8.4e-06 25.3 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 AEO69697.1 - 6.8e-21 72.2 1.1 0.00017 21.5 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 AEO69697.1 - 1.2e-17 63.5 8.1 1.2e-05 25.3 0.0 5.5 2 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO69697.1 - 4.7e-14 52.4 5.2 2.9e-06 27.6 0.1 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) NACHT PF05729.7 AEO69697.1 - 1.6e-08 34.3 0.0 1.8e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 AEO69697.1 - 0.066 13.1 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Methyltransf_24 PF13578.1 AEO69698.1 - 2.6e-13 50.6 0.0 4.4e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 AEO69698.1 - 2.1e-06 26.9 0.0 5.7e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 AEO69698.1 - 0.035 14.6 0.0 0.074 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF3885 PF13021.1 AEO69698.1 - 0.041 13.5 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) IDO PF01231.13 AEO69699.1 - 1.5e-84 283.9 0.0 2.7e-57 194.1 0.0 2.0 1 1 1 2 2 2 2 Indoleamine 2,3-dioxygenase HPP PF04982.8 AEO69700.1 - 2.1e-36 124.4 10.5 2.1e-36 124.4 7.3 1.6 2 0 0 2 2 2 1 HPP family RskA PF10099.4 AEO69700.1 - 0.061 13.0 4.1 0.48 10.1 2.6 2.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Ion_trans_2 PF07885.11 AEO69700.1 - 2.4 7.9 6.2 0.49 10.1 0.1 2.6 3 0 0 3 3 3 0 Ion channel Methyltransf_11 PF08241.7 AEO69702.1 - 1.9e-16 60.3 0.0 3.2e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO69702.1 - 1.5e-11 44.6 0.0 2.4e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO69702.1 - 2.2e-11 43.7 0.0 3.2e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO69702.1 - 3.8e-11 42.8 0.0 5.9e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO69702.1 - 1.1e-10 42.0 0.0 2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO69702.1 - 7.5e-10 39.0 0.0 1.2e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO69702.1 - 4.6e-09 36.3 0.5 4.6e-09 36.3 0.3 2.1 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 AEO69702.1 - 0.0049 15.9 0.0 0.0086 15.1 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 AEO69702.1 - 0.039 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Glyco_hydro_31 PF01055.21 AEO69703.1 - 4e-130 434.5 0.3 5e-130 434.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 AEO69703.1 - 4.8e-05 23.1 0.0 0.00022 21.0 0.0 2.2 2 1 0 2 2 2 1 Galactose mutarotase-like Tat PF00539.13 AEO69704.1 - 0.019 14.5 4.7 0.025 14.1 3.3 1.3 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) TadE PF07811.7 AEO69705.1 - 1.5 8.7 5.7 0.15 11.9 0.6 1.9 2 0 0 2 2 2 0 TadE-like protein AflR PF08493.5 AEO69706.1 - 4.3e-11 42.3 0.0 4.3e-11 42.3 0.0 2.7 2 1 0 2 2 2 1 Aflatoxin regulatory protein Fungal_trans PF04082.13 AEO69707.1 - 3.7e-15 55.4 0.3 5.5e-15 54.9 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO69707.1 - 1.2e-08 34.7 7.2 1.2e-08 34.7 5.0 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 AEO69708.1 - 1.7e-46 158.5 42.1 1.7e-46 158.5 29.2 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 AEO69708.1 - 0.2 11.1 7.5 0.041 13.3 2.1 2.3 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 AEO69709.1 - 3.8e-35 121.2 29.8 1.5e-34 119.2 20.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 AEO69709.1 - 0.00013 22.2 0.3 0.00044 20.6 0.2 1.9 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glyco_transf_22 PF03901.12 AEO69710.1 - 0.38 9.6 8.0 0.073 12.0 1.2 2.2 1 1 0 2 2 2 0 Alg9-like mannosyltransferase family Methyltransf_31 PF13847.1 AEO69711.1 - 1.5e-14 53.8 0.0 2.2e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO69711.1 - 8.7e-14 51.7 0.0 1.8e-13 50.7 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO69711.1 - 1.2e-10 40.9 0.0 5.1e-10 38.8 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 AEO69711.1 - 6.9e-10 38.8 0.0 1e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO69711.1 - 2e-08 34.4 0.0 3.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO69711.1 - 2.9e-07 30.5 0.1 5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO69711.1 - 8.1e-06 26.3 0.0 2.7e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO69711.1 - 0.00012 22.4 0.0 0.00027 21.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 AEO69711.1 - 0.001 18.2 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.15 AEO69711.1 - 0.0027 16.8 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 AEO69711.1 - 0.025 14.0 0.0 0.058 12.9 0.0 1.7 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 AEO69711.1 - 0.082 12.1 0.0 0.17 11.1 0.0 1.5 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_8 PF05148.10 AEO69711.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase FAD_binding_3 PF01494.14 AEO69713.1 - 4.6e-14 52.2 0.5 4.3e-08 32.5 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 AEO69713.1 - 1.2e-05 24.4 0.0 0.05 12.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO69713.1 - 1.6e-05 24.8 0.2 3.3e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 AEO69713.1 - 0.00012 22.3 0.1 0.0034 17.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO69713.1 - 0.0047 15.9 0.1 1.2 8.0 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.12 AEO69713.1 - 0.028 13.5 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 AEO69713.1 - 0.052 12.1 0.3 4.9 5.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 AEO69713.1 - 0.094 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO69713.1 - 0.16 10.4 0.0 1.9 6.8 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.11 AEO69713.1 - 0.18 11.2 0.2 0.32 10.4 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 AEO69713.1 - 0.21 11.7 0.0 0.36 10.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Mito_fiss_reg PF05308.6 AEO69715.1 - 0.016 14.5 0.9 0.027 13.8 0.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Peptidase_C14 PF00656.17 AEO69715.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Caspase domain DUF1777 PF08648.7 AEO69715.1 - 5.7 6.6 19.7 0.31 10.7 8.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) zf-RING_5 PF14634.1 AEO69716.1 - 2e-05 24.2 2.0 7.8e-05 22.3 0.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO69716.1 - 0.00051 20.0 0.5 0.00051 20.0 0.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AEO69716.1 - 0.0017 18.0 0.1 0.003 17.2 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 AEO69716.1 - 0.0079 15.9 2.2 0.016 15.0 0.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 AEO69716.1 - 0.0095 15.7 0.7 0.059 13.2 0.2 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 AEO69716.1 - 0.014 15.0 4.6 0.077 12.6 2.0 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO69716.1 - 0.015 14.9 4.4 0.041 13.5 3.1 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 AEO69716.1 - 0.051 13.1 1.6 1.2 8.7 0.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 AEO69716.1 - 0.083 12.4 0.5 0.083 12.4 0.3 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FYVE PF01363.16 AEO69716.1 - 0.14 12.1 3.9 0.62 9.9 2.7 2.0 1 1 0 1 1 1 0 FYVE zinc finger zf-UDP PF14569.1 AEO69716.1 - 0.41 10.4 3.5 0.24 11.1 0.8 1.8 1 1 1 2 2 2 0 Zinc-binding RING-finger C1_4 PF07975.7 AEO69716.1 - 0.81 9.7 4.5 9.3 6.3 3.2 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain PhzC-PhzF PF02567.11 AEO69718.1 - 1.1e-36 126.5 1.9 4.2e-24 85.2 0.0 2.4 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein Prp19 PF08606.6 AEO69718.1 - 4.5e-31 106.3 1.3 1.1e-30 105.1 0.9 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 AEO69718.1 - 2e-10 40.1 0.8 0.0036 17.1 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.6 AEO69718.1 - 2.1e-05 24.3 0.0 0.02 14.6 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A zf-Nse PF11789.3 AEO69718.1 - 0.06 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit tRNA-synt_His PF13393.1 AEO69719.1 - 6.6e-37 127.2 0.0 9.6e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 AEO69719.1 - 1.4e-14 54.0 0.0 2.5e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AEO69719.1 - 7.9e-10 38.5 0.1 3.6e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 AEO69719.1 - 0.0032 16.2 0.3 0.19 10.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) PRANC PF09372.5 AEO69720.1 - 4.3e-05 23.3 0.5 6.3e-05 22.8 0.3 1.6 1 1 0 1 1 1 1 PRANC domain DnaJ PF00226.26 AEO69722.1 - 0.0025 17.5 0.1 0.16 11.7 0.1 2.4 1 1 0 1 1 1 1 DnaJ domain Glyco_transf_15 PF01793.11 AEO69723.1 - 7.9e-132 439.2 1.8 9.8e-132 438.8 1.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_hydro_16 PF00722.16 AEO69724.1 - 1.7e-43 148.1 2.4 2.9e-43 147.2 1.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 AEO69724.1 - 0.077 12.9 12.2 0.22 11.5 8.5 1.7 1 0 0 1 1 1 0 Chitin recognition protein Myb_DNA-binding PF00249.26 AEO69725.1 - 4.6e-12 45.7 2.2 1.1e-06 28.6 0.6 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO69725.1 - 2.7e-11 43.3 0.6 6.1e-06 26.2 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO69727.1 - 0.0009 19.2 0.2 0.0019 18.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO69727.1 - 0.077 13.0 0.4 0.23 11.5 0.3 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain ILVD_EDD PF00920.16 AEO69728.1 - 4.2e-171 569.9 1.3 5.6e-171 569.5 0.9 1.1 1 0 0 1 1 1 1 Dehydratase family InvH PF04741.7 AEO69728.1 - 0.19 11.5 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 InvH outer membrane lipoprotein Ank PF00023.25 AEO69729.1 - 2.3e-32 109.1 7.0 1e-07 31.4 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 AEO69729.1 - 3.2e-30 104.2 1.3 5.7e-14 52.2 0.3 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AEO69729.1 - 8.3e-23 78.2 0.9 4e-05 23.4 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 AEO69729.1 - 1.2e-21 76.6 2.3 1.9e-08 34.6 0.1 4.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO69729.1 - 2.9e-20 71.8 8.4 1.2e-07 31.7 0.2 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Clr5 PF14420.1 AEO69729.1 - 6.1e-18 64.4 1.4 1e-17 63.7 1.0 1.3 1 0 0 1 1 1 1 Clr5 domain DUF4604 PF15377.1 AEO69730.1 - 9.2e-34 116.9 9.1 1.9e-33 115.9 6.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) COX5B PF01215.14 AEO69731.1 - 5.7e-40 136.1 0.0 7.1e-40 135.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb ADK_lid PF05191.9 AEO69731.1 - 0.064 12.9 0.5 0.12 12.0 0.3 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.5 AEO69731.1 - 0.081 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Zinc ribbon domain 4HBT_3 PF13622.1 AEO69732.1 - 9.6e-41 140.2 8.0 1.3e-40 139.7 5.5 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Ribosomal_60s PF00428.14 AEO69732.1 - 0.0068 16.7 1.4 0.016 15.5 1.0 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein Senescence_reg PF04520.8 AEO69732.1 - 0.18 12.2 1.1 0.33 11.4 0.1 1.9 2 0 0 2 2 2 0 Senescence regulator CHIPS PF11434.3 AEO69733.1 - 0.07 12.7 1.5 0.08 12.5 1.1 1.1 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS OPT PF03169.10 AEO69734.1 - 1.2e-164 549.2 52.2 1.4e-164 549.0 36.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TraV PF09676.5 AEO69735.1 - 2.6 8.7 10.7 3.9 8.1 2.7 2.5 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) OHCU_decarbox PF09349.5 AEO69736.1 - 1.7e-38 132.4 4.0 6.3e-38 130.5 2.8 1.9 1 1 0 1 1 1 1 OHCU decarboxylase UPF0278 PF08745.6 AEO69736.1 - 0.12 11.6 0.1 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 UPF0278 family Aldo_ket_red PF00248.16 AEO69737.1 - 1.8e-65 220.5 0.0 2.1e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2235 PF09994.4 AEO69738.1 - 1.3e-67 228.1 0.0 2.1e-67 227.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 AEO69738.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ank_5 PF13857.1 AEO69739.1 - 4e-15 55.4 2.4 7.1e-10 38.8 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 AEO69739.1 - 1e-14 54.5 0.1 5e-08 33.1 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AEO69739.1 - 1.2e-12 47.9 2.0 1.3e-06 28.7 0.0 4.5 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 AEO69739.1 - 5.9e-10 38.4 0.6 3.4e-05 23.4 0.0 4.6 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 AEO69739.1 - 3.4e-07 29.8 3.7 0.0013 18.7 0.0 4.4 6 0 0 6 6 6 2 Ankyrin repeat DUF4394 PF14339.1 AEO69741.1 - 0.0013 18.0 0.8 0.096 11.9 0.0 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4394) SGL PF08450.7 AEO69741.1 - 0.0014 18.0 0.2 0.0085 15.4 0.1 2.3 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 AEO69741.1 - 0.011 15.6 0.5 3.1 7.9 0.1 3.1 3 0 0 3 3 3 0 NHL repeat WND PF07861.6 AEO69741.1 - 0.02 13.9 6.6 0.095 11.7 0.2 3.0 2 1 1 3 3 3 0 WisP family N-Terminal Region GST_N_3 PF13417.1 AEO69742.1 - 5.2e-10 39.4 0.0 7.9e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 AEO69742.1 - 8.5e-08 32.2 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO69742.1 - 1e-07 31.8 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NDUF_B7 PF05676.8 AEO69743.1 - 0.0002 20.6 2.0 0.00038 19.8 1.4 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Defensin_1 PF00323.14 AEO69743.1 - 1.2 9.6 3.8 11 6.5 0.2 2.4 2 0 0 2 2 2 0 Mammalian defensin Osmo_MPGsynth PF09488.5 AEO69746.1 - 1.1e-115 386.4 0.0 1.3e-115 386.0 0.0 1.1 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) NAD_binding_10 PF13460.1 AEO69747.1 - 2.8e-14 53.5 0.0 8.5e-10 38.9 0.0 3.3 1 1 1 2 2 2 2 NADH(P)-binding NmrA PF05368.8 AEO69747.1 - 0.036 13.3 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 AEO69747.1 - 0.092 12.6 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Abhydrolase_5 PF12695.2 AEO69749.1 - 7.3e-17 61.4 0.2 1.2e-16 60.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO69749.1 - 3.6e-08 33.5 6.8 1e-05 25.5 4.3 2.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO69749.1 - 4.2e-06 26.4 0.1 5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 AEO69749.1 - 0.00048 19.4 0.0 0.00076 18.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family PhoPQ_related PF10142.4 AEO69749.1 - 0.0042 15.6 0.0 0.43 8.9 0.1 2.1 2 0 0 2 2 2 2 PhoPQ-activated pathogenicity-related protein Abhydrolase_4 PF08386.5 AEO69749.1 - 0.021 14.6 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_2 PF02230.11 AEO69749.1 - 0.029 13.8 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 AEO69749.1 - 0.031 13.5 0.3 1.5 8.0 0.3 2.2 1 1 1 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.15 AEO69749.1 - 0.054 13.7 0.1 0.33 11.1 0.1 1.9 2 0 0 2 2 2 0 Thioesterase domain DUF915 PF06028.6 AEO69749.1 - 0.091 11.8 0.0 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Glyco_hydro_3 PF00933.16 AEO69750.1 - 1.6e-16 60.1 0.0 1.8e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PrgH PF09480.5 AEO69751.1 - 0.057 12.2 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) GST_N PF02798.15 AEO69752.1 - 1.8e-12 47.2 0.0 4.1e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 AEO69752.1 - 4.7e-09 36.3 0.0 9.5e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO69752.1 - 6.3e-08 32.3 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 AEO69752.1 - 6.6e-08 32.4 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 AEO69752.1 - 7.3e-07 29.6 0.0 1.3e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AEO69752.1 - 6.7e-05 22.7 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_L18e PF00828.14 AEO69753.1 - 5.8e-16 59.0 0.1 8.8e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 PX PF00787.19 AEO69754.1 - 1.2e-18 66.9 0.1 2.4e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 PX domain Cullin_binding PF03556.10 AEO69755.1 - 1.2e-18 67.3 0.0 1.7e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Cullin binding Ribosomal_S6 PF01250.12 AEO69756.1 - 3.6e-09 36.3 0.0 4.1e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 DUF3716 PF12511.3 AEO69757.1 - 1.6e-10 40.4 4.7 2.9e-10 39.6 3.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF4618 PF15397.1 AEO69757.1 - 0.13 11.5 1.2 0.22 10.8 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Chs3p PF12271.3 AEO69758.1 - 1.8e-139 463.7 14.1 2e-139 463.5 9.8 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3382 PF11862.3 AEO69758.1 - 4.9 7.1 13.2 0.16 11.9 3.1 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF3382) CRA_rpt PF07046.6 AEO69759.1 - 2.3 8.2 5.1 0.5 10.3 1.0 1.8 2 0 0 2 2 2 0 Cytoplasmic repetitive antigen (CRA) like repeat ADH_N PF08240.7 AEO69760.1 - 8e-29 99.5 2.1 1.7e-28 98.5 1.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO69760.1 - 5.3e-17 61.5 0.1 9.1e-17 60.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO69760.1 - 2.7e-05 25.0 0.0 4.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 AEO69760.1 - 0.0024 17.0 0.1 0.004 16.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Arrestin_C PF02752.17 AEO69761.1 - 1.6e-16 60.6 0.0 1.2e-15 57.7 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 AEO69761.1 - 3.7e-07 30.0 6.9 0.00067 19.5 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain RR_TM4-6 PF06459.7 AEO69761.1 - 0.38 10.6 4.0 0.66 9.8 2.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.6 AEO69761.1 - 4.5 6.8 17.2 11 5.6 11.9 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.12 AEO69761.1 - 7.6 6.2 7.3 44 3.7 5.2 2.0 2 0 0 2 2 2 0 DDHD domain Cyclin PF08613.6 AEO69762.1 - 2.8e-16 60.2 0.0 4.2e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AEO69762.1 - 0.00033 20.2 0.1 0.00063 19.3 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Filament PF00038.16 AEO69763.1 - 2.4e-07 30.5 24.3 2.4e-07 30.5 16.8 6.4 1 1 4 5 5 5 1 Intermediate filament protein CCDC155 PF14662.1 AEO69763.1 - 8.5e-07 28.7 7.3 8.5e-07 28.7 5.0 6.3 2 2 4 6 6 4 2 Coiled-coil region of CCDC155 Reo_sigmaC PF04582.7 AEO69763.1 - 9.8e-07 28.2 39.7 0.0016 17.6 6.3 4.8 2 1 2 5 5 4 3 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 AEO69763.1 - 1.5e-06 26.3 111.0 0.00014 19.8 20.4 3.9 1 1 0 2 2 1 1 Myosin tail ATG16 PF08614.6 AEO69763.1 - 6.4e-06 26.1 44.2 0.00015 21.6 19.1 6.3 2 1 4 7 7 5 2 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 AEO69763.1 - 1.5e-05 24.8 2.8 1.5e-05 24.8 1.9 7.4 1 1 6 7 7 6 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 AEO69763.1 - 1.6e-05 24.5 98.4 0.0018 17.9 18.5 6.6 1 1 3 5 5 4 4 IncA protein Cortex-I_coil PF09304.5 AEO69763.1 - 9.8e-05 22.3 9.0 9.8e-05 22.3 6.3 9.6 1 1 6 8 8 7 3 Cortexillin I, coiled coil Spc7 PF08317.6 AEO69763.1 - 0.00077 18.2 18.4 0.00077 18.2 12.8 6.1 1 1 5 6 6 6 3 Spc7 kinetochore protein AAA_13 PF13166.1 AEO69763.1 - 0.00084 17.9 74.1 0.011 14.2 19.3 4.5 1 1 4 5 5 5 3 AAA domain TMF_DNA_bd PF12329.3 AEO69763.1 - 0.0016 18.2 11.9 0.0016 18.2 8.3 11.1 4 1 8 12 12 11 4 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 AEO69763.1 - 0.0023 17.0 9.0 0.0023 17.0 6.2 6.2 1 1 5 6 6 6 5 Autophagy protein Apg6 MscS_porin PF12795.2 AEO69763.1 - 0.0036 16.6 21.2 0.0036 16.6 14.7 6.7 1 1 4 6 6 6 2 Mechanosensitive ion channel porin domain Baculo_PEP_C PF04513.7 AEO69763.1 - 0.01 15.6 47.8 0.011 15.5 8.2 6.3 3 2 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.1 AEO69763.1 - 0.026 13.7 84.4 0.011 14.9 3.1 5.5 1 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding AAA_27 PF13514.1 AEO69763.1 - 0.029 12.0 112.0 0.0011 16.7 52.0 2.5 1 1 1 2 2 2 0 AAA domain BLOC1_2 PF10046.4 AEO69763.1 - 0.18 11.9 0.1 0.18 11.9 0.1 7.8 4 3 4 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vac_Fusion PF02346.11 AEO69763.1 - 5.3 6.5 11.4 0.4 10.1 0.1 3.7 3 0 0 3 3 3 0 Chordopoxvirus fusion protein DUF4200 PF13863.1 AEO69763.1 - 6.4 6.7 108.8 2.2 8.2 0.2 8.0 1 1 3 7 7 7 0 Domain of unknown function (DUF4200) SnoaL_4 PF13577.1 AEO69764.1 - 6.2e-08 32.6 0.0 1.5e-07 31.3 0.0 1.8 1 1 1 2 2 2 1 SnoaL-like domain Thioredoxin PF00085.15 AEO69765.1 - 6.7e-26 89.9 0.0 8.5e-26 89.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AEO69765.1 - 1.7e-07 31.4 0.2 7.9e-06 26.0 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AEO69765.1 - 4.7e-07 29.8 0.0 6.6e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 AEO69765.1 - 1.9e-05 24.6 0.0 3.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 AEO69765.1 - 0.00018 21.1 0.1 0.002 17.7 0.1 2.0 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AEO69765.1 - 0.0039 16.7 0.2 0.57 9.7 0.0 2.2 1 1 1 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 AEO69765.1 - 0.01 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DIM1 PF02966.11 AEO69765.1 - 0.053 13.0 0.0 0.067 12.7 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 HyaE PF07449.6 AEO69765.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE PgaD PF13994.1 AEO69768.1 - 0.028 13.8 0.1 0.051 13.0 0.1 1.3 1 0 0 1 1 1 0 PgaD-like protein NicO PF03824.11 AEO69768.1 - 0.038 13.2 0.0 0.053 12.8 0.0 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein CDC27 PF09507.5 AEO69768.1 - 8.1 5.5 6.6 14 4.8 4.6 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Zn_clus PF00172.13 AEO69771.1 - 1e-09 38.1 8.0 1e-09 38.1 5.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO69771.1 - 1.1e-06 27.7 0.2 1.5e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ctr PF04145.10 AEO69772.1 - 1.3e-39 135.5 0.6 1.5e-39 135.3 0.4 1.1 1 0 0 1 1 1 1 Ctr copper transporter family YfhO PF09586.5 AEO69772.1 - 0.29 9.1 7.1 0.3 9.0 2.4 1.9 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Transgly_assoc PF04226.8 AEO69772.1 - 1.8 8.7 6.3 11 6.1 0.7 2.4 2 0 0 2 2 2 0 Transglycosylase associated protein Sensor PF13796.1 AEO69772.1 - 2.7 7.5 6.7 28 4.2 1.3 1.9 1 1 0 1 1 1 0 Putative sensor DUF1049 PF06305.6 AEO69772.1 - 9.5 5.7 6.1 35 3.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Zn_clus PF00172.13 AEO69773.1 - 2.7e-07 30.3 8.1 4.7e-07 29.5 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 AEO69774.1 - 1.9e-15 57.1 1.5 2.4e-15 56.8 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO69774.1 - 1.2e-09 38.1 0.3 1.7e-09 37.6 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO69774.1 - 0.00011 22.1 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 AEO69774.1 - 0.0051 16.5 0.2 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 AEO69774.1 - 0.04 12.8 0.1 0.056 12.3 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Arif-1 PF06770.6 AEO69775.1 - 1.3 8.3 8.4 4.1 6.7 0.5 2.4 2 0 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) 5_nucleotid_C PF02872.13 AEO69776.1 - 1.1e-07 31.8 0.0 2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 AEO69776.1 - 0.0051 16.2 0.1 0.0086 15.4 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase peroxidase PF00141.18 AEO69777.1 - 2.3e-88 295.5 0.0 8.4e-46 156.3 0.0 2.3 2 0 0 2 2 2 2 Peroxidase GST_C PF00043.20 AEO69777.1 - 0.036 14.0 0.0 5.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF2306 PF10067.4 AEO69780.1 - 3.2e-12 46.4 2.7 3.2e-12 46.4 1.8 2.1 3 0 0 3 3 3 1 Predicted membrane protein (DUF2306) PrgI PF12666.2 AEO69780.1 - 0.01 15.9 0.3 0.01 15.9 0.2 2.5 1 1 1 2 2 2 0 PrgI family protein adh_short PF00106.20 AEO69781.1 - 2.4e-26 92.6 2.1 2.8e-26 92.4 1.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO69781.1 - 2.3e-10 40.4 1.2 3e-10 40.0 0.8 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO69781.1 - 9.5e-10 38.6 0.0 1.1e-09 38.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 AEO69781.1 - 8.1e-05 22.7 0.5 0.00012 22.1 0.3 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO69781.1 - 0.0044 16.4 0.3 0.0054 16.2 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 AEO69781.1 - 0.018 13.9 0.1 0.028 13.3 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain p450 PF00067.17 AEO69782.1 - 5.4e-57 193.3 0.0 6.3e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Gram_pos_anchor PF00746.16 AEO69782.1 - 4.9 7.0 6.9 35 4.3 3.7 2.4 2 0 0 2 2 2 0 Gram positive anchor DUF2839 PF10999.3 AEO69783.1 - 4.3 7.4 7.0 11 6.0 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) RhoGAP PF00620.22 AEO69785.1 - 3e-16 59.4 0.0 5.3e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain HCMV_UL139 PF12507.3 AEO69785.1 - 0.03 14.4 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein Methyltransf_23 PF13489.1 AEO69786.1 - 0.0037 16.9 0.0 0.0046 16.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO69786.1 - 0.004 17.7 0.0 0.0058 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO69786.1 - 0.012 16.0 0.0 0.024 15.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PTS_2-RNA PF01885.11 AEO69787.1 - 1.5e-12 47.2 0.0 3.6e-12 45.9 0.0 1.6 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family 6PGD PF00393.14 AEO69788.1 - 3.8e-69 233.1 0.0 4.6e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 AEO69788.1 - 2e-31 109.0 0.0 4.3e-31 107.9 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 AEO69788.1 - 0.00049 19.3 0.1 0.0011 18.1 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 AEO69788.1 - 0.00088 18.9 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 AEO69788.1 - 0.0072 16.0 0.0 0.019 14.6 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_11 PF14833.1 AEO69788.1 - 0.053 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 AEO69788.1 - 0.08 13.3 0.0 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AP_endonuc_2 PF01261.19 AEO69789.1 - 1.3e-34 119.3 0.0 4e-34 117.7 0.0 1.8 2 1 0 2 2 2 1 Xylose isomerase-like TIM barrel MFS_1 PF07690.11 AEO69790.1 - 1.7e-44 152.0 54.7 4.4e-43 147.3 36.9 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO69790.1 - 6.4e-16 57.6 17.7 6.4e-16 57.6 12.3 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 AEO69790.1 - 7.9e-16 57.6 14.4 7.9e-16 57.6 10.0 3.4 1 1 3 4 4 4 2 Sugar (and other) transporter MFS_1_like PF12832.2 AEO69790.1 - 0.32 10.8 6.4 1.4 8.7 0.1 3.1 2 1 1 3 3 3 0 MFS_1 like family DUF3318 PF11780.3 AEO69790.1 - 1 8.8 5.9 0.19 11.3 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) DZR PF12773.2 AEO69791.1 - 8e-05 22.3 1.3 0.00015 21.5 0.9 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 AEO69791.1 - 0.00038 19.5 6.3 0.0014 17.7 4.4 1.9 1 1 0 1 1 1 1 zinc-ribbon domain DUF1469 PF07332.6 AEO69791.1 - 0.004 16.8 0.4 2.5 7.8 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1469) DUF1218 PF06749.7 AEO69791.1 - 0.012 16.0 2.2 0.038 14.4 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) zinc_ribbon_2 PF13240.1 AEO69791.1 - 0.026 14.0 8.1 0.2 11.2 5.7 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 AEO69791.1 - 0.055 12.9 10.1 0.35 10.4 0.8 2.4 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain CD34_antigen PF06365.7 AEO69791.1 - 0.11 12.1 0.3 0.14 11.7 0.2 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF805 PF05656.9 AEO69791.1 - 0.45 10.3 3.0 1.5 8.6 2.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Nudix_N_2 PF14803.1 AEO69791.1 - 0.46 10.2 8.4 0.94 9.2 0.7 2.4 1 1 1 2 2 2 0 Nudix N-terminal Syndecan PF01034.15 AEO69791.1 - 0.86 9.3 3.9 0.36 10.5 0.2 2.0 2 0 0 2 2 2 0 Syndecan domain ECF-ribofla_trS PF07155.7 AEO69791.1 - 3.9 7.1 6.6 32 4.1 4.6 2.0 1 1 0 1 1 1 0 ECF-type riboflavin transporter, S component HNH_2 PF13391.1 AEO69792.1 - 2.1e-09 37.0 0.4 6e-09 35.5 0.2 1.8 1 0 0 1 1 1 1 HNH endonuclease MFS_1 PF07690.11 AEO69793.1 - 8.9e-36 123.3 55.0 4.5e-35 120.9 38.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO69793.1 - 5e-11 41.5 27.8 1.9e-10 39.5 18.7 2.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NMO PF03060.10 AEO69794.1 - 3.5e-37 128.2 11.4 1.9e-35 122.5 7.9 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 AEO69794.1 - 1.1e-09 37.7 0.0 0.00025 20.0 2.7 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 AEO69794.1 - 2.6e-06 26.5 3.4 4.3e-06 25.8 2.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 AEO69794.1 - 0.12 11.2 1.0 0.24 10.2 0.7 1.4 1 1 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.16 AEO69794.1 - 0.95 8.3 3.3 0.37 9.6 0.6 1.5 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase NIF PF03031.13 AEO69796.1 - 1.3e-38 132.1 0.0 1.8e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF3749 PF12568.3 AEO69796.1 - 0.097 12.2 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Metallophos PF00149.23 AEO69798.1 - 1.1e-08 34.7 3.3 6.7e-08 32.1 2.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Fungal_trans PF04082.13 AEO69799.1 - 2.4e-14 52.8 0.0 3.5e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO69799.1 - 4.5e-08 32.8 7.3 1e-07 31.7 5.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF718 PF05336.8 AEO69799.1 - 0.073 12.8 0.4 12 5.7 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF718) CGI-121 PF08617.5 AEO69800.1 - 2.1e-42 144.5 0.0 2.4e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Pro_dh PF01619.13 AEO69801.1 - 7.6e-39 133.5 0.0 1.1e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase HTH_5 PF01022.15 AEO69801.1 - 0.061 13.0 0.1 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Gene66 PF02053.10 AEO69802.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Gene 66 (IR5) protein Tim17 PF02466.14 AEO69802.1 - 0.13 12.3 5.9 0.31 11.0 4.1 1.7 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Asp PF00026.18 AEO69804.1 - 8.4e-77 258.5 3.8 9.7e-77 258.3 2.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO69804.1 - 1.7e-07 31.3 0.0 2.7e-06 27.4 0.0 2.7 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO69804.1 - 7.5e-06 26.3 1.1 0.0007 20.0 0.2 2.8 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 AEO69804.1 - 0.042 13.4 0.1 0.13 11.7 0.0 1.9 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal Acyl_transf_3 PF01757.17 AEO69805.1 - 3.4e-33 114.8 21.8 1.2e-32 113.1 15.1 1.7 1 1 0 1 1 1 1 Acyltransferase family DUF418 PF04235.7 AEO69805.1 - 0.0015 18.2 3.0 0.0015 18.2 2.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF418) RseC_MucC PF04246.7 AEO69805.1 - 9.3 5.8 8.0 1.8 8.1 0.1 3.3 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC OPT PF03169.10 AEO69806.1 - 1.3e-83 281.5 46.5 1.6e-83 281.2 32.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Sugar_tr PF00083.19 AEO69807.1 - 1.1e-103 347.2 21.4 1.2e-103 347.0 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO69807.1 - 3.4e-22 78.6 27.5 4.6e-22 78.2 19.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO69807.1 - 0.00033 18.9 2.2 0.00033 18.9 1.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BNR PF02012.15 AEO69808.1 - 4 7.6 5.9 1.1 9.3 0.1 3.2 3 0 0 3 3 3 0 BNR/Asp-box repeat Zn_clus PF00172.13 AEO69809.1 - 5.6e-05 22.9 3.6 0.00013 21.8 2.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.19 AEO69810.1 - 1.4e-30 106.5 3.7 8.8e-30 103.8 0.4 2.8 2 1 0 2 2 2 2 Beta-lactamase Glyco_tranf_2_3 PF13641.1 AEO69811.1 - 1.3e-23 83.9 0.2 1.7e-23 83.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 AEO69811.1 - 9.7e-07 28.6 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 AEO69811.1 - 2.5e-06 26.9 0.1 1.5e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF3844 PF12955.2 AEO69813.1 - 6.1e-34 116.2 1.6 9.3e-34 115.6 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 AEO69813.1 - 2 8.6 7.9 0.45 10.7 1.9 2.3 2 0 0 2 2 2 0 EGF-like domain NTR2 PF15458.1 AEO69814.1 - 2.4e-76 256.3 10.5 4e-76 255.6 7.3 1.4 1 0 0 1 1 1 1 Nineteen complex-related protein 2 ASFV_J13L PF05568.6 AEO69814.1 - 0.22 11.0 1.7 0.52 9.8 1.2 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein LSM PF01423.17 AEO69815.1 - 1.4e-19 69.4 0.4 1.6e-19 69.2 0.3 1.0 1 0 0 1 1 1 1 LSM domain WW PF00397.21 AEO69816.1 - 8.9e-07 28.6 6.6 1.8e-06 27.7 4.6 1.5 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.4 AEO69816.1 - 1.6e-05 25.0 10.7 1.6e-05 25.0 7.4 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF1183 PF06682.7 AEO69816.1 - 0.005 16.4 11.4 0.005 16.4 7.9 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1183) SR-25 PF10500.4 AEO69816.1 - 0.0084 15.6 21.8 0.012 15.0 15.1 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Rick_17kDa_Anti PF05433.10 AEO69816.1 - 0.009 15.6 5.7 0.009 15.6 3.9 2.6 1 1 2 3 3 3 2 Glycine zipper 2TM domain DUF755 PF05501.6 AEO69816.1 - 0.029 14.4 14.7 0.063 13.3 10.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Daxx PF03344.10 AEO69816.1 - 0.99 7.8 41.2 1.2 7.4 28.5 1.1 1 0 0 1 1 1 0 Daxx Family Gly-zipper_OmpA PF13436.1 AEO69816.1 - 1.1 8.9 9.0 2.3 7.8 6.2 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain NPR3 PF03666.8 AEO69816.1 - 7.7 4.9 19.3 11 4.4 13.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_C14 PF00656.17 AEO69817.1 - 1e-68 231.7 0.0 1.3e-68 231.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain RGS PF00615.14 AEO69818.1 - 0.00076 19.5 0.0 0.024 14.7 0.0 2.2 2 0 0 2 2 2 1 Regulator of G protein signaling domain Serglycin PF04360.7 AEO69818.1 - 2.2 7.9 6.8 3.7 7.2 4.7 1.3 1 0 0 1 1 1 0 Serglycin AXE1 PF05448.7 AEO69819.1 - 0.046 12.2 0.0 0.086 11.3 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Zip PF02535.17 AEO69820.1 - 5.5e-49 166.8 0.5 7.2e-49 166.5 0.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF3357 PF11837.3 AEO69820.1 - 1.8 8.4 3.8 13 5.6 0.0 3.8 3 2 2 5 5 5 0 Domain of unknown function (DUF3357) DOMON PF03351.12 AEO69821.1 - 0.0026 17.6 0.0 0.0044 16.9 0.0 1.3 1 0 0 1 1 1 1 DOMON domain DXP_synthase_N PF13292.1 AEO69822.1 - 0.11 11.4 1.5 0.2 10.5 1.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DUF2413 PF10310.4 AEO69823.1 - 2.7e-149 497.7 0.0 3.1e-149 497.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 AEO69823.1 - 0.012 15.6 0.3 0.029 14.3 0.2 1.6 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain DUF605 PF04652.11 AEO69823.1 - 0.92 8.8 20.4 1.5 8.1 14.1 1.3 1 0 0 1 1 1 0 Vta1 like Med3 PF11593.3 AEO69823.1 - 1 8.5 7.2 1.3 8.1 5.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-MYND PF01753.13 AEO69825.1 - 0.0011 18.7 9.6 0.0023 17.7 6.6 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 AEO69825.1 - 0.51 10.0 5.4 1.2 8.8 3.8 1.6 1 0 0 1 1 1 0 HIT zinc finger Ribosomal_L14 PF00238.14 AEO69826.1 - 3.3e-32 110.8 0.0 3.7e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Malic_M PF03949.10 AEO69827.1 - 5.3e-80 268.6 0.1 6.9e-80 268.2 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 AEO69827.1 - 3.9e-65 218.8 0.0 6e-65 218.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Glyco_hydro_75 PF07335.6 AEO69828.1 - 9.8e-38 129.4 0.0 1.3e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 CFEM PF05730.6 AEO69829.1 - 9.9e-07 28.4 3.0 1.5e-06 27.8 2.1 1.3 1 0 0 1 1 1 1 CFEM domain HET PF06985.6 AEO69831.1 - 2.3e-18 66.6 0.1 3e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Colipase-like PF15083.1 AEO69832.1 - 0.0024 17.7 2.7 0.39 10.6 0.2 2.1 2 0 0 2 2 2 2 Colipase-like Colipase PF01114.13 AEO69832.1 - 0.38 10.2 9.9 0.63 9.5 1.0 2.3 2 0 0 2 2 2 0 Colipase, N-terminal domain AMP-binding PF00501.23 AEO69833.1 - 2.9e-73 246.6 0.0 6.7e-73 245.4 0.0 1.5 1 1 1 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO69833.1 - 7.8e-07 29.9 0.0 2.1e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pex14_N PF04695.8 AEO69833.1 - 0.0019 18.2 3.0 0.0042 17.1 2.1 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sporozoite_P67 PF05642.6 AEO69833.1 - 0.66 7.7 8.7 0.95 7.2 6.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Dicty_REP PF05086.7 AEO69833.1 - 0.67 7.6 8.4 0.9 7.2 5.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 AEO69833.1 - 3 5.6 17.0 4.5 5.1 11.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 AEO69833.1 - 4.3 7.1 26.0 8.1 6.2 18.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Cu-oxidase_3 PF07732.10 AEO69834.1 - 1.2e-42 144.3 0.7 1.2e-42 144.3 0.5 2.8 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 AEO69834.1 - 2.7e-28 98.2 10.2 1.4e-25 89.3 0.8 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 AEO69834.1 - 2.1e-19 69.9 0.0 1e-14 54.7 0.0 3.4 3 1 0 3 3 3 2 Multicopper oxidase Campylo_MOMP PF05538.6 AEO69834.1 - 0.1 10.9 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Campylobacter major outer membrane protein DUF1399 PF07173.7 AEO69838.1 - 8.2e-20 71.4 6.0 1.8e-15 57.4 0.2 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1399) DUF1045 PF06299.7 AEO69838.1 - 0.022 14.4 0.2 0.053 13.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) APH PF01636.18 AEO69839.1 - 0.012 15.3 1.7 0.012 15.3 1.2 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family APH PF01636.18 AEO69840.1 - 6.8e-08 32.5 0.0 8.6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family 2OG-FeII_Oxy PF03171.15 AEO69842.1 - 2.1e-13 50.3 0.0 3.3e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 AEO69842.1 - 4e-11 43.4 0.0 6.6e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal M20_dimer PF07687.9 AEO69844.1 - 2.9e-06 26.9 0.1 6.2e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 AEO69844.1 - 0.00034 20.1 6.6 0.00065 19.2 4.5 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3437 PF11919.3 AEO69844.1 - 0.064 12.9 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) DUF4360 PF14273.1 AEO69845.1 - 1.8e-40 138.5 0.2 2.2e-40 138.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) SKG6 PF08693.5 AEO69847.1 - 0.015 14.6 0.3 0.015 14.6 0.2 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF1191 PF06697.7 AEO69847.1 - 0.076 11.8 0.1 0.88 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) Granulin PF00396.13 AEO69847.1 - 1.2 9.2 7.0 1 9.4 1.8 2.4 2 0 0 2 2 2 0 Granulin Atg14 PF10186.4 AEO69848.1 - 1.3e-20 73.5 0.0 2.2e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 AEO69848.1 - 0.078 12.5 2.8 0.18 11.3 1.9 1.5 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 AEO69848.1 - 0.22 10.5 3.8 8.7 5.2 3.9 2.2 3 0 0 3 3 3 0 Autophagy protein Apg6 Spc7 PF08317.6 AEO69848.1 - 2.5 6.6 6.6 4.1 5.9 4.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ABC_tran_2 PF12848.2 AEO69848.1 - 5.4 6.9 8.5 11 5.9 5.9 1.5 1 0 0 1 1 1 0 ABC transporter LysM PF01476.15 AEO69849.1 - 6.1e-22 77.2 0.0 5.3e-07 29.4 0.0 3.2 3 0 0 3 3 3 3 LysM domain UPF0203 PF05254.7 AEO69849.1 - 0.037 13.8 0.2 0.62 9.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Glyco_hydro_18 PF00704.23 AEO69851.1 - 9.5e-53 179.8 0.6 5.4e-52 177.3 0.2 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.15 AEO69851.1 - 5.2e-09 35.8 0.1 0.0048 16.7 0.0 3.4 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.14 AEO69851.1 - 3.5e-05 23.6 5.7 3.5e-05 23.6 3.9 3.4 3 0 0 3 3 3 1 Chitin recognition protein DUF3142 PF11340.3 AEO69851.1 - 0.11 12.1 0.0 0.33 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3142) DUF3785 PF12653.2 AEO69851.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) Pyr_redox_2 PF07992.9 AEO69852.1 - 8.5e-22 78.0 0.1 1e-21 77.7 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO69852.1 - 9.1e-07 29.1 0.2 0.015 15.3 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO69852.1 - 9.4e-07 28.7 1.5 0.054 13.2 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.9 AEO69852.1 - 3.1e-06 25.9 0.2 0.0016 16.9 0.1 2.6 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.19 AEO69852.1 - 1.5e-05 24.0 6.5 0.00015 20.7 4.5 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 AEO69852.1 - 0.0001 21.5 0.2 0.00019 20.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 AEO69852.1 - 0.00019 21.4 0.3 0.00047 20.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO69852.1 - 0.00096 18.1 5.3 0.001 18.0 0.4 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 AEO69852.1 - 0.0016 17.5 0.2 0.0044 16.1 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 AEO69852.1 - 0.01 14.9 0.8 0.019 14.0 0.6 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 AEO69852.1 - 0.012 14.2 0.2 0.02 13.5 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.7 AEO69852.1 - 0.013 14.4 0.3 0.031 13.2 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 AEO69852.1 - 0.013 14.3 4.8 0.016 14.0 0.7 2.7 2 1 1 3 3 3 0 Glucose inhibited division protein A Pyr_redox PF00070.22 AEO69852.1 - 0.046 14.1 0.6 1.6 9.1 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO69852.1 - 0.15 10.9 0.1 10 4.8 0.1 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Fic PF02661.13 AEO69853.1 - 4.3e-20 72.2 0.0 1.2e-19 70.7 0.0 1.8 2 0 0 2 2 2 1 Fic/DOC family Parvo_NS1 PF01057.12 AEO69853.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Methyltransf_25 PF13649.1 AEO69857.1 - 7.2e-11 42.3 0.0 1.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO69857.1 - 8e-09 35.8 0.0 1.7e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO69857.1 - 9.2e-08 31.8 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO69857.1 - 2.4e-07 31.1 0.0 4.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO69857.1 - 0.00014 22.3 0.0 0.00039 20.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain AdoMet_MTase PF07757.8 AEO69857.1 - 0.064 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Ubie_methyltran PF01209.13 AEO69857.1 - 0.066 12.3 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ank_5 PF13857.1 AEO69858.1 - 1.3e-17 63.4 8.1 6.3e-09 35.7 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 AEO69858.1 - 1.2e-12 48.0 3.9 1.3e-06 28.6 0.5 3.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AEO69858.1 - 1.5e-11 43.3 3.9 0.0072 16.4 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 AEO69858.1 - 2.9e-10 40.3 6.8 0.0003 21.1 0.1 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 AEO69858.1 - 4.2e-09 35.7 8.7 0.0011 18.7 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat XLF PF09302.6 AEO69859.1 - 3.1e-38 131.2 0.0 5e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 XLF (XRCC4-like factor) Fork_head PF00250.13 AEO69861.1 - 3.2e-13 49.5 0.0 5.4e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Fork head domain Cactin_mid PF10312.4 AEO69862.1 - 4.4e-65 218.5 0.5 6e-65 218.0 0.3 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 AEO69862.1 - 8.1e-55 183.7 4.7 1.3e-54 183.0 3.2 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF1087 PF06465.8 AEO69862.1 - 0.00069 19.4 3.5 0.25 11.2 0.2 2.5 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1087) WD40 PF00400.27 AEO69863.1 - 6.4e-16 57.5 7.0 2e-07 30.6 0.4 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Ribosomal_L37ae PF01780.14 AEO69863.1 - 0.042 13.7 0.8 0.14 12.0 0.6 1.8 1 0 0 1 1 1 0 Ribosomal L37ae protein family Gemini_mov PF01708.11 AEO69864.1 - 0.039 13.5 0.0 0.039 13.5 0.0 2.9 4 0 0 4 4 4 0 Geminivirus putative movement protein DUF4083 PF13314.1 AEO69864.1 - 1.2 8.9 3.2 32 4.4 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF2267 PF10025.4 AEO69865.1 - 0.053 13.5 0.8 1.1 9.3 0.7 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) Bacteriocin_IId PF09221.5 AEO69865.1 - 0.13 12.2 2.0 0.21 11.5 0.9 1.7 1 1 1 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like RII_binding_1 PF10522.4 AEO69865.1 - 0.22 11.7 1.2 13 6.3 0.0 3.5 3 0 0 3 3 3 0 RII binding domain p450 PF00067.17 AEO69867.1 - 7e-66 222.6 0.0 8.9e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 AEO69868.1 - 1.5e-36 125.8 46.9 3.7e-36 124.5 32.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO69868.1 - 6.1e-20 70.9 12.4 9.9e-20 70.2 8.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 AEO69868.1 - 4e-10 38.8 12.4 4e-10 38.8 8.6 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter DUF1129 PF06570.6 AEO69868.1 - 0.16 11.2 5.9 0.39 9.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) AA_permease_2 PF13520.1 AEO69869.1 - 4.4e-57 193.5 48.4 5.5e-57 193.2 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO69869.1 - 1.6e-24 86.0 39.7 2.2e-24 85.6 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease PIRT PF15099.1 AEO69869.1 - 6.2 6.0 8.2 0.7 9.1 0.2 3.1 4 0 0 4 4 4 0 Phosphoinositide-interacting protein family Fructosamin_kin PF03881.9 AEO69870.1 - 1.1e-28 100.0 0.0 1.5e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 AEO69870.1 - 0.0002 21.1 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 AEO69870.1 - 0.039 13.0 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase adh_short PF00106.20 AEO69871.1 - 1.6e-27 96.4 0.1 2.3e-27 95.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO69871.1 - 1.8e-24 86.8 0.0 2.3e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO69871.1 - 2.2e-08 33.9 0.0 3.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO69871.1 - 0.00039 19.9 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 AEO69871.1 - 0.0024 17.6 0.1 0.0067 16.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 AEO69871.1 - 0.036 13.2 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2974 PF11187.3 AEO69871.1 - 0.097 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Ribosomal_S21e PF01249.13 AEO69872.1 - 5.2e-39 132.0 0.1 5.7e-39 131.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Slx4 PF09494.5 AEO69873.1 - 1.3e-24 85.7 0.0 2e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Slx4 endonuclease NUDIX PF00293.23 AEO69874.1 - 1.1e-09 38.0 0.0 1.4e-09 37.7 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain AAA PF00004.24 AEO69875.1 - 4.8e-15 55.9 0.0 9.2e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO69875.1 - 8e-05 22.7 1.4 0.029 14.4 0.0 3.3 1 1 1 3 3 3 1 AAA domain AAA_19 PF13245.1 AEO69875.1 - 0.00047 19.8 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 AEO69875.1 - 0.00068 19.6 1.3 0.0037 17.2 0.0 2.7 3 1 1 4 4 4 1 AAA ATPase domain AAA_17 PF13207.1 AEO69875.1 - 0.0022 18.7 0.3 0.55 11.0 0.0 3.3 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.9 AEO69875.1 - 0.0049 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 AEO69875.1 - 0.022 13.7 0.0 0.078 12.0 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 AEO69875.1 - 0.073 13.3 0.0 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 AEO69875.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 AEO69875.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AEO69876.1 - 6e-06 26.0 0.0 2.5e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 AEO69876.1 - 0.00026 21.1 0.0 0.00071 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO69876.1 - 0.00074 19.5 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 AEO69876.1 - 0.0013 19.0 0.0 0.0029 17.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.17 AEO69876.1 - 0.0038 16.1 0.0 0.0076 15.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 AEO69876.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 AEO69876.1 - 0.019 15.1 0.1 0.086 13.0 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.13 AEO69876.1 - 0.022 14.2 0.1 0.058 12.8 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF258 PF03193.11 AEO69876.1 - 0.079 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 AEO69876.1 - 0.1 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 AEO69876.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AEO69876.1 - 0.16 11.8 0.0 0.75 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 AEO69876.1 - 0.2 11.8 0.0 0.69 10.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Bax1-I PF01027.15 AEO69877.1 - 7.5e-32 110.6 9.5 1.1e-31 110.1 6.6 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 COX14 PF14880.1 AEO69877.1 - 0.42 10.2 2.5 5.2 6.7 1.2 2.8 2 0 0 2 2 2 0 Cytochrome oxidase c assembly cNMP_binding PF00027.24 AEO69878.1 - 2.6e-37 126.5 0.0 3.2e-18 65.3 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 AEO69878.1 - 4.7e-12 44.6 0.5 2.4 8.5 0.0 7.8 8 0 0 8 8 8 3 Leucine Rich repeat F-box-like PF12937.2 AEO69878.1 - 3.5e-07 29.8 1.3 1.3e-06 27.9 0.9 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO69878.1 - 3.5e-07 29.7 0.4 3.5e-07 29.7 0.3 2.8 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.28 AEO69878.1 - 2.6e-05 23.6 3.5 17 5.9 0.0 7.0 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.1 AEO69878.1 - 9.1e-05 22.1 0.5 0.97 9.2 0.0 3.9 2 1 1 3 3 3 1 Leucine rich repeat Fungal_trans PF04082.13 AEO69880.1 - 5.2e-21 74.6 0.0 7.6e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO69880.1 - 2.9e-09 36.6 11.0 5.7e-09 35.7 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3760 PF12586.3 AEO69880.1 - 0.0089 15.8 0.4 11 5.9 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3760) Glyco_hydro_63 PF03200.11 AEO69881.1 - 1e-191 638.8 0.0 2.5e-191 637.5 0.0 1.5 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 AEO69881.1 - 0.015 13.9 0.2 0.035 12.7 0.1 1.5 1 1 0 1 1 1 0 Trehalase DUF3632 PF12311.3 AEO69883.1 - 7.6e-14 51.9 1.5 1.1e-13 51.4 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) NUDIX PF00293.23 AEO69885.1 - 4.3e-08 32.8 0.1 4.9e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain CAP_N PF01213.14 AEO69887.1 - 4.5 6.4 4.7 9.7 5.3 3.2 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal GST_N_3 PF13417.1 AEO69888.1 - 6.1e-10 39.1 0.1 1.3e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO69888.1 - 1.1e-06 28.4 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO69888.1 - 0.00022 21.0 1.1 0.00042 20.1 0.8 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AEO69888.1 - 0.00041 20.7 0.1 0.00077 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AEO69888.1 - 0.034 14.3 0.0 0.1 12.7 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 AEO69888.1 - 0.094 12.7 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Velvet PF11754.3 AEO69889.1 - 0.012 15.1 0.1 0.22 11.0 0.0 2.0 1 1 1 2 2 2 0 Velvet factor Velvet PF11754.3 AEO69890.1 - 0.00056 19.5 0.1 0.0012 18.4 0.1 1.5 1 1 0 1 1 1 1 Velvet factor Aldo_ket_red PF00248.16 AEO69891.1 - 1.8e-67 227.1 0.0 2.3e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family L27 PF02828.11 AEO69892.1 - 0.22 11.2 1.9 0.54 9.9 0.1 2.2 2 0 0 2 2 2 0 L27 domain Pkinase PF00069.20 AEO69893.1 - 3.9e-35 121.2 0.0 5.1e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO69893.1 - 1.9e-15 56.6 0.0 3.2e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO69893.1 - 0.0093 15.7 2.6 3.4 7.3 0.0 3.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 AEO69893.1 - 0.048 12.6 0.0 0.2 10.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like ABC1 PF03109.11 AEO69893.1 - 0.056 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Neisseria_TspB PF05616.8 AEO69894.1 - 0.29 9.4 10.2 0.33 9.2 7.1 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF3936 PF13072.1 AEO69895.1 - 0.26 10.7 2.3 0.37 10.2 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3936) DUF566 PF04484.7 AEO69895.1 - 1.1 8.7 3.4 1.6 8.1 2.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ferritin_2 PF13668.1 AEO69897.1 - 8.1e-15 54.9 0.0 1.2e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain HXXEE PF13787.1 AEO69898.1 - 2.3e-15 56.9 2.1 2.3e-15 56.9 1.5 1.6 2 0 0 2 2 2 1 Protein of unknown function with HXXEE motif adh_short PF00106.20 AEO69900.1 - 7.5e-27 94.2 0.1 9.4e-27 93.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO69900.1 - 2e-13 50.6 0.0 2.5e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 AEO69900.1 - 8.7e-11 42.1 0.1 1.2e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 AEO69900.1 - 1.2e-10 41.3 0.0 1.6e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO69900.1 - 5.9e-06 25.8 0.1 1e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 AEO69900.1 - 1.5e-05 24.1 0.1 0.00011 21.3 0.1 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 AEO69900.1 - 0.00014 21.9 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 AEO69900.1 - 0.012 15.0 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 AEO69900.1 - 0.013 15.5 0.1 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain THF_DHG_CYH_C PF02882.14 AEO69900.1 - 0.022 13.8 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 AEO69900.1 - 0.024 15.0 0.0 0.075 13.4 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Wax2_C PF12076.3 AEO69900.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 WAX2 C-terminal domain NAD_binding_2 PF03446.10 AEO69900.1 - 0.029 14.1 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.12 AEO69900.1 - 0.05 12.4 0.0 0.076 11.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Ldh_1_N PF00056.18 AEO69900.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NmrA PF05368.8 AEO69901.1 - 9.5e-19 67.5 0.0 1.1e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO69901.1 - 6e-10 39.4 0.0 1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF1996 PF09362.5 AEO69903.1 - 7.8e-88 294.0 1.0 9.7e-88 293.7 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CopD PF05425.8 AEO69906.1 - 1.2 9.3 14.6 2.2 8.5 3.1 2.8 1 1 1 2 2 2 0 Copper resistance protein D Glyco_hydro_43 PF04616.9 AEO69907.1 - 2.8e-19 69.2 0.0 5.8e-19 68.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 p450 PF00067.17 AEO69909.1 - 1.1e-52 179.1 0.0 1.5e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cellulase PF00150.13 AEO69910.1 - 8.5e-59 199.0 2.9 1.2e-58 198.5 2.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 AEO69910.1 - 2e-12 46.5 11.0 2e-12 46.5 7.6 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain FAD_binding_4 PF01565.18 AEO69911.1 - 7.2e-24 83.8 0.0 9.9e-24 83.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 AEO69912.1 - 1.9e-14 53.5 0.3 2.6e-14 53.1 0.2 1.3 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain Pyr_redox_3 PF13738.1 AEO69913.1 - 1.1e-23 84.3 0.1 2.6e-23 83.1 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AEO69913.1 - 1.3e-14 53.3 0.0 5.7e-13 47.9 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 AEO69913.1 - 3.6e-09 36.5 0.0 3.5e-07 30.1 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 AEO69913.1 - 1.6e-07 30.5 0.4 1e-05 24.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 AEO69913.1 - 1.5e-06 27.4 0.1 4.3e-05 22.6 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.19 AEO69913.1 - 8.3e-06 24.9 4.2 0.0025 16.7 0.6 3.8 3 1 1 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.12 AEO69913.1 - 9.2e-05 21.6 0.4 0.0028 16.7 0.0 2.9 4 0 0 4 4 4 1 Thi4 family Pyr_redox_2 PF07992.9 AEO69913.1 - 0.0018 18.1 0.0 0.13 12.0 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO69913.1 - 0.0022 18.3 0.1 0.41 11.0 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AEO69913.1 - 0.019 13.8 1.0 2.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 AEO69913.1 - 0.044 13.5 0.6 30 4.3 0.0 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 AEO69913.1 - 0.06 12.1 1.2 0.16 10.7 0.0 2.2 3 0 0 3 3 3 0 FAD binding domain Pkinase_Tyr PF07714.12 AEO69914.1 - 1e-12 47.7 0.0 1.4e-11 43.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 AEO69914.1 - 2.2e-12 46.6 0.0 3e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 AEO69914.1 - 0.00041 20.1 0.0 0.0007 19.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO69914.1 - 0.0014 17.7 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AEO69914.1 - 0.022 13.7 0.0 0.044 12.7 0.0 1.5 1 1 0 1 1 1 0 Kinase-like DUF922 PF06037.6 AEO69918.1 - 0.16 11.2 0.2 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) GST_N_3 PF13417.1 AEO69919.1 - 2.3e-05 24.5 0.0 0.00011 22.3 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO69919.1 - 0.00017 21.4 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO69919.1 - 0.00064 19.5 0.3 0.0027 17.5 0.2 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Serglycin PF04360.7 AEO69919.1 - 0.024 14.3 0.1 5.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Serglycin adh_short_C2 PF13561.1 AEO69921.1 - 5.5e-20 72.1 0.0 6.4e-12 45.7 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AEO69921.1 - 1.6e-08 34.6 0.1 2.3e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 AEO69921.1 - 0.00049 20.1 0.8 0.00059 19.8 0.5 1.5 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 AEO69921.1 - 0.0031 17.2 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 AEO69921.1 - 0.015 15.0 3.6 0.024 14.4 1.7 1.9 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.1 AEO69921.1 - 0.03 14.5 0.0 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding TPR_12 PF13424.1 AEO69922.1 - 6e-05 22.9 8.5 0.0056 16.5 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TSA PF03249.8 AEO69922.1 - 0.088 11.3 0.0 0.088 11.3 0.0 3.2 2 1 1 3 3 3 0 Type specific antigen TPR_10 PF13374.1 AEO69922.1 - 0.76 9.8 11.6 18 5.4 1.1 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO69922.1 - 5.3 7.9 18.7 4.4 8.2 1.2 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF2254 PF10011.4 AEO69923.1 - 0.048 12.1 0.0 0.057 11.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) HemY_N PF07219.8 AEO69923.1 - 0.097 12.2 0.5 0.15 11.6 0.4 1.2 1 0 0 1 1 1 0 HemY protein N-terminus DUF3593 PF12159.3 AEO69923.1 - 0.12 12.1 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) HET PF06985.6 AEO69925.1 - 6.7e-37 126.7 0.0 7.8e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-U1 PF06220.7 AEO69926.1 - 0.033 13.7 5.2 0.11 12.1 0.2 2.6 2 0 0 2 2 2 0 U1 zinc finger zf-DBF PF07535.7 AEO69926.1 - 0.044 13.4 2.8 0.12 12.0 0.1 2.3 2 0 0 2 2 2 0 DBF zinc finger zf-C2H2_4 PF13894.1 AEO69926.1 - 0.63 10.4 6.0 0.77 10.2 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO69926.1 - 8.2 6.7 6.1 1 9.6 0.5 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding adh_short PF00106.20 AEO69927.1 - 3.4e-18 66.1 0.2 3.9e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO69927.1 - 1.7e-09 37.6 0.1 2.1e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 AEO69927.1 - 0.054 13.5 0.8 0.35 10.9 0.5 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 AEO69927.1 - 0.055 12.3 0.0 0.067 12.1 0.0 1.1 1 0 0 1 1 1 0 Male sterility protein Fungal_trans PF04082.13 AEO69928.1 - 5.2e-14 51.7 0.1 1.4e-13 50.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO69928.1 - 1.4e-06 28.0 13.1 2.5e-06 27.2 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2231 PF09990.4 AEO69929.1 - 3 8.2 7.9 73 3.7 0.0 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) MFS_1 PF07690.11 AEO69930.1 - 1.3e-30 106.3 28.2 1.3e-30 106.3 19.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.1 AEO69930.1 - 1.8 8.6 8.7 0.29 11.1 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Peptidase_A8 PF01252.13 AEO69930.1 - 6.1 6.4 12.5 2.6 7.6 0.5 3.3 3 0 0 3 3 3 0 Signal peptidase (SPase) II His_Phos_1 PF00300.17 AEO69931.1 - 4.1e-13 49.7 0.0 9e-13 48.6 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) 2-Hacid_dh_C PF02826.14 AEO69933.1 - 9.9e-45 151.8 0.1 4.3e-44 149.7 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AEO69933.1 - 2.9e-06 26.7 0.0 4.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain adh_short PF00106.20 AEO69935.1 - 8.8e-23 81.0 8.6 1.4e-22 80.3 6.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO69935.1 - 2.4e-12 46.9 5.7 5.1e-12 45.8 4.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO69935.1 - 7.3e-06 25.9 0.2 1.2e-05 25.2 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ras PF00071.17 AEO69936.1 - 8.2e-43 145.5 0.0 1.1e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO69936.1 - 7.2e-16 58.7 0.0 1e-15 58.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO69936.1 - 1.2e-10 40.9 0.0 6.7e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family PduV-EutP PF10662.4 AEO69936.1 - 0.00038 19.9 0.0 0.22 11.0 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 AEO69936.1 - 0.00083 18.5 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 AEO69936.1 - 0.0024 17.7 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 AEO69936.1 - 0.0032 17.4 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 AEO69936.1 - 0.0064 16.6 0.0 0.017 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 AEO69936.1 - 0.018 14.2 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 AEO69936.1 - 0.023 14.4 0.1 0.11 12.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 AEO69936.1 - 0.024 13.8 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 AEO69936.1 - 0.028 14.4 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 AEO69936.1 - 0.03 14.3 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AEO69936.1 - 0.03 13.9 0.0 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 AEO69936.1 - 0.037 13.7 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 AEO69936.1 - 0.078 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Glyco_hydro_2_N PF02837.13 AEO69937.1 - 2e-10 40.4 0.0 5e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 AEO69937.1 - 2.8e-10 40.6 0.2 1.6e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 AEO69937.1 - 2.9e-06 26.4 0.0 4.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF402 PF04167.8 AEO69937.1 - 0.16 11.8 2.4 1.6 8.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF402) ADH_N PF08240.7 AEO69938.1 - 5.3e-31 106.5 0.9 1.3e-30 105.3 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO69938.1 - 1.7e-24 85.8 0.8 3.5e-24 84.8 0.5 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO69938.1 - 2.8e-05 25.0 0.4 8.5e-05 23.4 0.1 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 AEO69938.1 - 0.00083 19.9 0.0 0.0019 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 AEO69938.1 - 0.0098 15.2 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 AEO69938.1 - 0.012 16.0 0.2 0.13 12.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 AEO69938.1 - 0.021 13.9 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 AEO69938.1 - 0.026 12.9 0.4 0.034 12.6 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein AdoHcyase_NAD PF00670.16 AEO69938.1 - 0.13 12.0 0.9 0.27 11.0 0.2 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Lycopene_cycl PF05834.7 AEO69938.1 - 1.7 7.4 3.7 9.2 5.0 0.7 2.1 1 1 1 2 2 2 0 Lycopene cyclase protein HNH_2 PF13391.1 AEO69939.1 - 1.4e-17 63.1 0.1 2.3e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF1479 PF07350.7 AEO69940.1 - 0.0079 14.7 0.4 0.013 13.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Mur_ligase_M PF08245.7 AEO69940.1 - 0.043 13.8 0.0 0.4 10.7 0.0 2.3 1 1 0 1 1 1 0 Mur ligase middle domain Mur_ligase_M PF08245.7 AEO69941.1 - 0.00017 21.6 0.3 0.77 9.7 0.9 2.5 2 0 0 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.16 AEO69941.1 - 0.053 13.5 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Mitofilin PF09731.4 AEO69942.1 - 5.9e-159 530.4 5.1 8.3e-159 529.9 3.5 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein 4HB_MCP_1 PF12729.2 AEO69942.1 - 0.02 14.2 7.5 0.04 13.2 5.2 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction HAUS6_N PF14661.1 AEO69942.1 - 0.46 9.7 9.6 0.9 8.8 6.6 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Ras PF00071.17 AEO69943.1 - 5e-59 198.3 0.4 5.7e-59 198.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO69943.1 - 3.9e-19 69.3 0.1 7.1e-19 68.4 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AEO69943.1 - 8.9e-16 57.6 0.1 1.1e-15 57.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AEO69943.1 - 1.8e-08 34.0 0.0 2.6e-08 33.5 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AEO69943.1 - 2.2e-08 33.5 0.0 2.6e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AEO69943.1 - 9.8e-06 25.5 0.0 1.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 AEO69943.1 - 0.014 14.6 0.2 0.07 12.3 0.0 2.1 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 AEO69943.1 - 0.038 14.1 0.1 1.5 8.9 0.1 2.5 1 1 0 1 1 1 0 AAA domain Carboxyl_trans PF01039.17 AEO69943.1 - 0.042 12.1 0.1 0.046 12.0 0.0 1.1 1 0 0 1 1 1 0 Carboxyl transferase domain G-alpha PF00503.15 AEO69943.1 - 0.12 11.0 0.3 9.6 4.7 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Syja_N PF02383.13 AEO69944.1 - 1.7e-91 306.3 0.0 2.1e-91 306.0 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain N_methyl_2 PF13544.1 AEO69945.1 - 0.034 13.6 0.1 0.12 11.9 0.1 2.0 1 0 0 1 1 1 0 Type IV pilin N-term methylation site GFxxxE DnaJ PF00226.26 AEO69946.1 - 6.6e-17 61.0 1.2 6.6e-17 61.0 0.9 2.3 2 0 0 2 2 2 1 DnaJ domain UPF0183 PF03676.9 AEO69947.1 - 1.6e-38 132.3 0.0 1.6e-22 79.6 0.0 5.2 4 1 0 4 4 4 4 Uncharacterised protein family (UPF0183) Kinesin PF00225.18 AEO69948.1 - 2.3e-112 375.0 1.4 2.3e-112 375.0 1.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 AEO69948.1 - 2.3e-07 31.0 0.2 2.3e-07 31.0 0.1 4.6 3 2 2 5 5 5 1 Kinesin-associated microtubule-binding HAD_2 PF13419.1 AEO69949.1 - 4.3e-27 95.4 0.0 6.1e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase RRN9 PF10680.4 AEO69950.1 - 1.2e-19 69.7 0.1 4.5e-17 61.5 0.0 2.8 2 0 0 2 2 2 2 RNA polymerase I specific transcription initiation factor zf-C2H2 PF00096.21 AEO69950.1 - 6.8e-05 22.9 7.9 0.023 14.9 0.1 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO69950.1 - 0.001 19.2 10.1 0.068 13.5 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 AEO69950.1 - 0.076 13.2 0.8 5.6 7.4 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain RVT_1 PF00078.22 AEO69951.1 - 9.9e-05 21.7 0.7 0.00013 21.4 0.5 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PQQ PF01011.16 AEO69952.1 - 0.088 12.3 0.1 0.38 10.3 0.1 2.1 2 0 0 2 2 2 0 PQQ enzyme repeat Pescadillo_N PF06732.6 AEO69954.1 - 5.4e-111 370.3 0.1 5.4e-111 370.3 0.0 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 AEO69954.1 - 3.9e-10 39.7 0.0 1.2e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PIG-U PF06728.8 AEO69955.1 - 2.5e-117 391.9 28.6 2.8e-117 391.7 19.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.8 AEO69955.1 - 5.5e-05 22.9 5.4 0.00016 21.4 3.7 1.7 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) GHMP_kinases_N PF00288.21 AEO69956.1 - 0.021 14.8 0.1 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases N terminal domain RVT_1 PF00078.22 AEO69957.1 - 0.00054 19.3 0.4 0.00068 19.0 0.3 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Plasmod_dom_1 PF09715.5 AEO69957.1 - 0.092 12.6 1.2 0.26 11.2 0.6 1.9 1 1 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) Plasmod_dom_1 PF09715.5 AEO69958.1 - 1.2 9.1 7.1 0.1 12.5 1.2 2.0 2 1 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) Tom37 PF10568.4 AEO69960.1 - 1.3e-16 60.6 0.6 1.9e-16 60.1 0.0 1.6 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein Tom37_C PF11801.3 AEO69960.1 - 5.6e-15 55.6 0.0 2e-14 53.7 0.0 1.8 1 1 0 1 1 1 1 Tom37 C-terminal domain tRNA-synt_1 PF00133.17 AEO69961.1 - 3.9e-132 441.3 0.0 5e-132 440.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AEO69961.1 - 6.8e-17 61.6 0.0 1.2e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AEO69961.1 - 2.3e-12 46.3 0.0 0.0064 15.1 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 AEO69961.1 - 0.00038 20.0 4.9 0.00073 19.1 3.4 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 AEO69961.1 - 0.19 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.20 AEO69961.1 - 0.26 10.3 0.1 1.4 7.9 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Methyltransf_12 PF08242.7 AEO69962.1 - 7.8e-16 58.3 0.0 1.2e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO69962.1 - 4.4e-14 52.5 0.0 6.1e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO69962.1 - 1.1e-07 32.2 0.0 2.4e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO69962.1 - 8.2e-07 29.3 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO69962.1 - 2e-06 27.4 0.0 2.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO69962.1 - 3e-06 27.2 0.5 1.2e-05 25.2 0.2 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO69962.1 - 0.00027 21.5 0.0 0.00048 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO69962.1 - 0.00031 19.9 0.0 0.0024 17.0 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.7 AEO69962.1 - 0.00053 19.6 0.0 0.0008 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Peptidase_S9 PF00326.16 AEO69963.1 - 3.2e-06 26.5 0.0 4e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO69963.1 - 0.00094 18.9 0.0 0.0014 18.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO69963.1 - 0.0077 16.1 0.4 0.0085 15.9 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 AEO69963.1 - 0.013 14.6 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase DEAD PF00270.24 AEO69964.1 - 9.2e-26 90.3 0.0 5.7e-14 51.9 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO69964.1 - 5.2e-23 80.7 0.0 1.4e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO69964.1 - 2.2e-05 24.4 0.4 0.00063 19.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PYC_OADA PF02436.13 AEO69964.1 - 0.061 12.7 1.2 0.12 11.7 0.8 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain TRAP_alpha PF03896.11 AEO69964.1 - 3.3 6.6 10.4 0.36 9.7 0.1 2.6 3 0 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.8 AEO69964.1 - 7.5 6.1 31.4 0.24 10.9 1.7 3.2 2 1 1 3 3 3 0 Sigma-70, non-essential region SPRY PF00622.23 AEO69965.1 - 0.0037 17.3 0.0 0.0076 16.3 0.0 1.5 1 1 0 1 1 1 1 SPRY domain Peptidase_S15 PF02129.13 AEO69966.1 - 5.4e-39 134.2 2.9 3e-34 118.6 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 AEO69966.1 - 4.8e-24 85.4 0.0 6.8e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 AEO69966.1 - 1.6e-08 34.6 0.8 6.1e-08 32.8 0.2 2.1 1 1 2 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AEO69966.1 - 0.068 13.0 0.1 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF1479 PF07350.7 AEO69967.1 - 2.7e-07 29.4 0.0 0.0018 16.8 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) PhyH PF05721.8 AEO69967.1 - 7.4e-06 26.1 0.1 6.9e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 AEO69967.1 - 0.048 13.9 0.0 0.098 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Fungal_trans PF04082.13 AEO69968.1 - 7.9e-14 51.1 0.0 1.3e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO69968.1 - 4.3e-10 39.3 6.1 1.1e-09 38.0 4.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 AEO69969.1 - 1.1e-18 67.1 30.1 1.6e-17 63.2 16.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO69969.1 - 3.9e-06 25.7 19.6 9.6e-06 24.4 13.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Na_Ca_ex PF01699.19 AEO69970.1 - 9.2e-39 132.2 34.8 8.6e-23 80.4 10.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Peptidase_C14 PF00656.17 AEO69971.1 - 0.059 13.0 0.0 0.084 12.5 0.0 1.1 1 0 0 1 1 1 0 Caspase domain PemK PF02452.12 AEO69972.1 - 0.02 15.0 0.0 0.051 13.7 0.0 1.6 1 1 0 1 1 1 0 PemK-like protein PhoD PF09423.5 AEO69973.1 - 0.00083 18.0 0.1 0.0012 17.4 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase Peptidase_S8 PF00082.17 AEO69974.1 - 4.7e-53 180.1 2.7 7.2e-53 179.5 1.8 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 AEO69974.1 - 1e-28 98.9 0.2 1.8e-28 98.1 0.2 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain Vps5 PF09325.5 AEO69975.1 - 1.4e-13 50.7 0.7 5.7e-08 32.2 0.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 AEO69975.1 - 1.4e-08 34.5 0.5 6.7e-08 32.3 0.4 1.8 1 1 0 1 1 1 1 BAR domain IncA PF04156.9 AEO69975.1 - 3e-05 23.7 0.6 0.00016 21.3 0.0 2.0 2 0 0 2 2 2 1 IncA protein PX PF00787.19 AEO69975.1 - 0.00018 21.2 0.0 0.00047 19.9 0.0 1.7 1 0 0 1 1 1 1 PX domain FlaC_arch PF05377.6 AEO69975.1 - 0.0092 15.8 0.1 0.17 11.7 0.0 2.4 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 AEO69975.1 - 0.022 13.9 0.8 0.029 13.5 0.1 1.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein eIF3_subunit PF08597.5 AEO69975.1 - 0.039 13.5 9.1 0.053 13.0 3.2 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF4404 PF14357.1 AEO69975.1 - 0.18 12.2 8.1 0.41 11.0 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Laminin_II PF06009.7 AEO69975.1 - 0.36 10.5 3.5 0.47 10.2 0.5 2.3 2 1 0 2 2 2 0 Laminin Domain II ADIP PF11559.3 AEO69975.1 - 0.98 9.3 5.1 6.1 6.7 0.1 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Prefoldin_2 PF01920.15 AEO69975.1 - 2.9 7.6 10.3 0.91 9.3 1.0 2.9 3 0 0 3 3 3 0 Prefoldin subunit Spc7 PF08317.6 AEO69975.1 - 4 6.0 6.7 5.2 5.6 2.3 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein LETM1 PF07766.8 AEO69976.1 - 1.1e-111 372.1 1.3 1.9e-111 371.4 0.9 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 AEO69976.1 - 1.4e-05 24.4 0.1 0.051 13.1 0.0 3.5 3 0 0 3 3 3 2 SAP domain ADK PF00406.17 AEO69977.1 - 5.4e-37 126.9 0.0 3.4e-21 75.7 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 AEO69977.1 - 3.1e-14 52.3 0.0 5.9e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 AEO69977.1 - 5.4e-05 23.5 0.0 0.00035 20.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO69977.1 - 0.00015 22.5 0.0 0.00027 21.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AEO69977.1 - 0.00016 21.5 0.1 0.00066 19.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO69977.1 - 0.05 13.3 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RVT_1 PF00078.22 AEO69978.1 - 0.077 12.3 0.1 0.096 12.0 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3414 PF11894.3 AEO69980.1 - 0.017 12.0 0.7 0.017 12.0 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3414) RVT_1 PF00078.22 AEO69980.1 - 0.08 12.2 1.0 0.098 12.0 0.7 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_76 PF03663.9 AEO69981.1 - 3.2e-18 66.2 8.0 1.3e-13 51.1 0.0 4.4 3 2 1 4 4 4 3 Glycosyl hydrolase family 76 Mucin PF01456.12 AEO69981.1 - 0.15 11.8 17.1 0.035 13.8 7.5 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Serglycin PF04360.7 AEO69981.1 - 1.2 8.8 9.4 20 4.9 0.0 2.3 2 0 0 2 2 2 0 Serglycin FAD-oxidase_C PF02913.14 AEO69982.1 - 4.5e-60 203.0 0.1 6.6e-60 202.4 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 AEO69982.1 - 1.1e-39 135.0 0.0 2.7e-39 133.8 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Clr5 PF14420.1 AEO69983.1 - 6.4e-20 70.8 1.3 3.8e-19 68.3 0.4 2.4 2 0 0 2 2 2 1 Clr5 domain DUF4187 PF13821.1 AEO69983.1 - 0.11 12.1 0.1 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Amidase PF01425.16 AEO69984.1 - 2.7e-68 230.8 1.0 2.7e-68 230.8 0.7 1.6 2 0 0 2 2 2 1 Amidase Troponin PF00992.15 AEO69985.1 - 0.033 14.2 13.5 0.96 9.5 5.4 2.2 2 0 0 2 2 2 0 Troponin Selenoprotein_S PF06936.6 AEO69985.1 - 0.036 13.5 1.4 0.063 12.8 1.0 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) Glyco_tranf_2_3 PF13641.1 AEO69988.1 - 2.8e-21 76.3 0.1 4e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 AEO69988.1 - 2.1e-08 33.6 0.0 4.6e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 AEO69988.1 - 6.7e-05 22.6 0.3 0.0014 18.3 0.1 3.3 3 1 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_64 PF09258.5 AEO69988.1 - 0.00014 21.1 0.1 0.00028 20.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain AAA_18 PF13238.1 AEO69990.1 - 0.055 13.7 0.0 0.56 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain GWT1 PF06423.7 AEO69992.1 - 1.2e-44 151.7 0.7 3.5e-44 150.2 0.5 1.9 1 0 0 1 1 1 1 GWT1 Pkinase PF00069.20 AEO69993.1 - 4.3e-64 216.1 0.0 8.2e-64 215.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO69993.1 - 1.7e-36 125.5 0.0 3.6e-31 108.1 0.1 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AEO69993.1 - 2.3e-05 23.4 0.0 0.025 13.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 AEO69993.1 - 0.00056 19.7 0.2 0.0068 16.1 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO69993.1 - 0.0068 15.4 0.1 0.013 14.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AEO69993.1 - 0.014 14.7 0.1 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family RRM_1 PF00076.17 AEO69994.1 - 2.9e-16 58.8 0.0 4.4e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO69994.1 - 4.2e-11 42.6 0.0 6.5e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO69994.1 - 2.5e-09 36.8 0.0 4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AEO69994.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Nop14 PF04147.7 AEO69995.1 - 0.17 9.7 12.7 0.28 9.0 8.8 1.3 1 0 0 1 1 1 0 Nop14-like family PBP_sp32 PF07222.7 AEO69995.1 - 0.18 10.9 4.7 0.32 10.1 3.3 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pox_Ag35 PF03286.9 AEO69995.1 - 0.7 9.3 18.8 0.022 14.2 6.3 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CDC27 PF09507.5 AEO69995.1 - 0.83 8.8 23.3 0.13 11.4 6.3 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 PBP1_TM PF14812.1 AEO69995.1 - 3.5 8.0 27.3 0.32 11.3 3.7 3.0 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PGA2 PF07543.7 AEO69995.1 - 5.2 6.8 15.4 2.4 7.9 8.5 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF3759 PF12585.3 AEO69996.1 - 0.0029 17.4 3.3 0.0029 17.4 2.3 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3759) DUF4196 PF13846.1 AEO69996.1 - 0.011 16.0 0.3 0.017 15.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) GATA PF00320.22 AEO69997.1 - 4.1e-16 58.0 5.4 7.4e-16 57.2 3.7 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 AEO69997.1 - 9.7e-13 48.0 0.0 1.7e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 AEO69997.1 - 1.1e-09 38.5 0.0 2.5e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 AEO69997.1 - 1.5e-07 31.1 0.0 4e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.1 AEO69997.1 - 4e-07 29.9 0.0 7.5e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 AEO69997.1 - 1.6e-06 28.0 0.0 3.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 AEO69997.1 - 0.0072 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 PAS domain TF_Zn_Ribbon PF08271.7 AEO69997.1 - 0.13 11.5 0.9 0.67 9.3 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4428 PF14471.1 AEO69997.1 - 1 9.1 4.4 0.34 10.6 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) tRNA-synt_2 PF00152.15 AEO69998.1 - 2.9e-12 46.0 0.0 3.7e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) SbcCD_C PF13558.1 AEO69999.1 - 4.8e-12 45.6 0.0 1.5e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 AEO69999.1 - 3.8e-09 37.1 116.7 1.5e+04 -20.2 80.9 7.5 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 AEO69999.1 - 1.2e-08 35.3 16.8 2e-06 28.0 1.2 4.3 4 2 0 4 4 4 2 AAA domain AAA_15 PF13175.1 AEO69999.1 - 1.2e-08 34.4 0.0 1.1e-05 24.6 0.0 5.8 5 2 0 5 5 5 2 AAA ATPase domain SMC_N PF02463.14 AEO69999.1 - 3.6e-07 29.6 0.0 3.6e-07 29.6 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 AEO69999.1 - 7.3e-07 28.0 0.3 0.00035 19.1 0.0 7.3 3 1 3 7 7 7 3 AAA domain AAA_29 PF13555.1 AEO69999.1 - 0.0015 18.0 0.0 0.0034 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 AEO69999.1 - 0.026 14.2 0.6 0.18 11.4 0.0 2.9 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF948 PF06103.6 AEO69999.1 - 0.28 11.0 21.7 0.28 11.0 0.4 6.0 5 2 1 6 6 6 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 AEO69999.1 - 2.6 7.7 63.8 0.066 12.9 4.9 7.8 4 2 3 7 7 7 0 Laminin Domain II PPP4R2 PF09184.6 AEO70000.1 - 1e-08 35.1 0.0 1e-08 35.1 0.0 2.9 4 0 0 4 4 4 2 PPP4R2 CRPA PF05745.6 AEO70001.1 - 0.11 12.2 6.9 0.9 9.3 0.0 2.9 2 1 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF4418 PF14387.1 AEO70001.1 - 9.3 6.0 15.8 2.9 7.6 0.4 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4418) CLTH PF10607.4 AEO70002.1 - 1.4e-29 102.6 0.0 3e-29 101.5 0.0 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 AEO70002.1 - 1.1e-15 57.0 2.5 2.3e-15 56.0 1.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 AEO70002.1 - 0.00029 20.6 1.6 0.00047 19.9 1.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO70002.1 - 0.0031 17.5 2.4 0.0051 16.8 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO70002.1 - 0.0037 16.9 1.5 0.006 16.2 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AEO70002.1 - 0.051 13.4 2.8 0.09 12.6 1.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 AEO70002.1 - 0.065 12.9 2.2 0.11 12.1 1.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO70002.1 - 0.1 12.3 1.5 0.17 11.6 1.1 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Flagellin_C PF00700.16 AEO70002.1 - 0.14 12.3 0.1 0.34 11.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region zf-MIZ PF02891.15 AEO70002.1 - 0.44 10.0 3.4 0.34 10.4 1.3 1.6 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger PG_binding_1 PF01471.13 AEO70003.1 - 0.00064 19.6 0.1 0.47 10.4 0.0 2.9 2 0 0 2 2 2 2 Putative peptidoglycan binding domain DUF1490 PF07371.7 AEO70003.1 - 0.038 13.9 0.8 0.11 12.4 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1490) AAA_13 PF13166.1 AEO70003.1 - 0.058 11.8 0.1 0.085 11.3 0.1 1.1 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.7 AEO70003.1 - 0.079 13.2 0.2 7.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Myosin_tail_1 PF01576.14 AEO70003.1 - 0.091 10.4 3.6 0.13 9.9 2.5 1.1 1 0 0 1 1 1 0 Myosin tail Tropomyosin_1 PF12718.2 AEO70003.1 - 0.23 11.3 3.4 0.14 11.9 0.4 2.0 2 0 0 2 2 2 0 Tropomyosin like DivIC PF04977.10 AEO70003.1 - 0.36 10.3 2.8 2.2 7.8 0.1 2.5 1 1 0 2 2 2 0 Septum formation initiator IncA PF04156.9 AEO70003.1 - 0.42 10.1 2.9 0.77 9.3 2.0 1.3 1 0 0 1 1 1 0 IncA protein zf-Tim10_DDP PF02953.10 AEO70004.1 - 1.6e-19 68.9 2.5 1.8e-19 68.7 1.7 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 AEO70004.1 - 0.008 15.6 1.4 0.011 15.1 1.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) tRNA-synt_2 PF00152.15 AEO70005.1 - 1.2e-68 231.3 0.0 2.6e-68 230.2 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AEO70005.1 - 5.9e-12 45.2 0.0 9.5e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AEO70005.1 - 5.1e-06 25.8 0.0 0.015 14.5 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) PH_6 PF15406.1 AEO70008.1 - 2.8e-46 156.1 3.1 2.8e-46 156.1 2.2 3.9 4 0 0 4 4 4 1 Pleckstrin homology domain PH PF00169.24 AEO70008.1 - 0.0029 17.7 0.0 0.0077 16.4 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_4 PF15404.1 AEO70008.1 - 0.68 9.4 0.0 0.68 9.4 0.0 3.6 4 0 0 4 4 4 0 Pleckstrin homology domain HATPase_c PF02518.21 AEO70009.1 - 1.7e-24 85.6 0.0 3.3e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 AEO70009.1 - 5.3e-15 55.3 0.0 1.5e-14 53.9 0.0 1.8 1 1 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 AEO70009.1 - 2.5e-12 47.0 0.0 7.5e-10 39.1 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 AEO70009.1 - 5e-12 45.8 0.2 1.1e-05 25.4 0.0 3.5 3 0 0 3 3 3 2 PAS fold HisKA PF00512.20 AEO70009.1 - 1e-07 31.8 0.0 2.7e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.1 AEO70009.1 - 0.00047 19.9 0.0 0.0083 15.9 0.0 3.0 3 0 0 3 3 3 1 PAS domain GAF_2 PF13185.1 AEO70009.1 - 0.0029 18.1 0.0 0.084 13.3 0.0 2.7 2 0 0 2 2 2 1 GAF domain PAS PF00989.19 AEO70009.1 - 0.0055 16.4 0.0 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 PAS fold GAF_3 PF13492.1 AEO70009.1 - 0.065 13.3 0.0 0.23 11.5 0.0 2.0 1 0 0 1 1 1 0 GAF domain Aldedh PF00171.17 AEO70012.1 - 9e-167 555.0 0.1 1e-166 554.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPR_10 PF13374.1 AEO70013.1 - 1.9e-47 157.9 8.2 1.5e-11 43.8 0.1 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 AEO70013.1 - 2.2e-40 136.4 16.6 7.7e-16 57.8 0.1 4.1 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 AEO70013.1 - 4.3e-10 38.7 4.0 0.045 13.3 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 AEO70013.1 - 4.9e-10 38.5 8.6 0.075 12.9 0.1 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 AEO70013.1 - 6.3e-10 38.4 0.1 1.4 9.3 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 AEO70013.1 - 2.2e-09 36.4 9.2 0.019 14.7 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.9 AEO70013.1 - 3.4e-09 36.2 1.3 0.019 15.3 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.7 AEO70013.1 - 4.6e-08 32.6 2.0 0.07 12.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO70013.1 - 2.1e-07 31.4 6.1 0.0046 17.5 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO70013.1 - 4.4e-07 29.2 5.1 0.13 12.1 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 AEO70013.1 - 2.4e-06 27.7 4.6 0.46 10.8 0.1 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 AEO70013.1 - 9.5e-06 25.6 6.2 0.027 14.5 0.1 4.3 1 1 3 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 AEO70013.1 - 5.9e-05 23.1 1.4 0.068 13.3 0.4 3.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 AEO70013.1 - 0.00017 21.1 4.5 0.0043 16.6 0.4 2.8 1 1 2 3 3 3 2 TPR repeat TPR_14 PF13428.1 AEO70013.1 - 0.00021 21.6 9.7 1.4 9.7 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 AEO70013.1 - 0.0018 18.6 9.6 7.5 7.2 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3773 PF12608.3 AEO70013.1 - 0.0051 16.8 0.0 4.8 7.2 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3773) Med28 PF11594.3 AEO70013.1 - 0.0062 16.7 4.3 0.7 10.1 0.4 3.7 2 2 1 3 3 3 1 Mediator complex subunit 28 Mad3_BUB1_II PF08171.6 AEO70013.1 - 0.026 14.3 2.9 4.8 7.1 0.1 3.8 3 1 1 4 4 4 0 Mad3/BUB1 homology region 2 Osmo_CC PF08946.5 AEO70013.1 - 0.079 12.9 6.0 44 4.2 0.0 4.6 5 0 0 5 5 4 0 Osmosensory transporter coiled coil Phage_Nu1 PF07471.7 AEO70013.1 - 0.095 12.1 3.6 0.43 10.0 0.1 2.7 1 1 1 3 3 3 0 Phage DNA packaging protein Nu1 Coatomer_E PF04733.9 AEO70013.1 - 0.11 11.6 1.6 3.9 6.5 0.0 2.8 1 1 2 3 3 3 0 Coatomer epsilon subunit DUF2179 PF10035.4 AEO70013.1 - 0.15 11.7 0.4 5.5 6.6 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2179) DUF1897 PF09005.5 AEO70013.1 - 2.4 7.6 4.7 0.35 10.3 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1897) zf-Sec23_Sec24 PF04810.10 AEO70014.1 - 0.01 15.3 0.5 0.78 9.3 0.0 2.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Flg_hook PF02120.11 AEO70014.1 - 0.015 14.9 0.1 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK zf-C2H2_4 PF13894.1 AEO70014.1 - 0.53 10.7 11.1 1.9 9.0 0.6 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Phage_GP20 PF06810.6 AEO70015.1 - 0.034 13.5 0.3 0.074 12.4 0.2 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 Rad1 PF02144.11 AEO70017.1 - 3.5e-87 291.6 0.0 4e-87 291.4 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 UPF0197 PF05251.7 AEO70018.1 - 0.03 14.6 6.3 0.19 12.0 4.4 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0197) Claudin_2 PF13903.1 AEO70018.1 - 0.37 10.4 4.7 0.48 10.0 3.3 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Bromodomain PF00439.20 AEO70019.1 - 1.5e-26 92.0 0.4 2.9e-26 91.1 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 AEO70019.1 - 9.7e-10 38.4 0.1 2.2e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO70019.1 - 3.5e-09 36.5 0.0 7.3e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 AEO70019.1 - 0.076 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO70019.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Trehalase PF01204.13 AEO70020.1 - 4.4e-117 391.8 0.2 3.4e-116 388.9 0.1 1.9 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.9 AEO70020.1 - 7.2e-05 21.6 0.7 0.00027 19.7 0.5 1.8 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Beta_elim_lyase PF01212.16 AEO70021.1 - 9.1e-70 235.0 0.0 1.1e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 AEO70021.1 - 3.1e-05 22.4 0.0 4.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 AEO70021.1 - 0.1 11.6 0.0 0.29 10.1 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.13 AEO70022.1 - 0.0043 15.9 0.7 0.011 14.5 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Cep57_MT_bd PF06657.8 AEO70023.1 - 4.7e-25 87.3 0.1 4.7e-25 87.3 0.1 7.3 6 3 1 8 8 8 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 AEO70023.1 - 1e-16 60.6 9.2 1e-16 60.6 6.4 7.8 5 1 2 7 7 7 3 Centrosome localisation domain of PPC89 MerR_2 PF13591.1 AEO70023.1 - 0.00062 19.3 2.0 0.00062 19.3 1.4 5.6 6 0 0 6 6 6 1 MerR HTH family regulatory protein DUF812 PF05667.6 AEO70023.1 - 0.0013 17.3 0.4 0.0013 17.3 0.3 4.7 1 1 3 5 5 5 1 Protein of unknown function (DUF812) ADIP PF11559.3 AEO70023.1 - 0.0028 17.5 13.8 0.0028 17.5 9.6 6.3 2 1 4 6 6 6 2 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 AEO70023.1 - 0.01 16.0 81.3 0.034 14.4 4.7 8.3 6 2 2 8 8 8 0 Protein of unknown function (DUF904) IncA PF04156.9 AEO70023.1 - 0.042 13.4 82.6 0.039 13.5 4.9 6.3 2 1 3 5 5 5 0 IncA protein Reo_sigmaC PF04582.7 AEO70023.1 - 2.7 7.1 11.9 0.61 9.2 2.3 3.4 2 1 1 4 4 4 0 Reovirus sigma C capsid protein Laminin_I PF06008.9 AEO70023.1 - 4.7 6.4 63.6 2.5 7.3 9.0 4.3 3 1 1 4 4 4 0 Laminin Domain I DUF972 PF06156.8 AEO70023.1 - 5.5 7.3 57.1 4.8 7.5 3.7 7.8 2 1 5 7 7 7 0 Protein of unknown function (DUF972) Ribophorin_II PF05817.9 AEO70024.1 - 4.9e-23 81.2 2.8 4.8e-22 77.9 1.9 1.9 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II CDP-OH_P_transf PF01066.16 AEO70026.1 - 8.5e-17 61.3 6.3 8.5e-17 61.3 4.4 2.6 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PX PF00787.19 AEO70027.1 - 1.7e-21 76.1 0.1 2.6e-21 75.5 0.1 1.3 1 0 0 1 1 1 1 PX domain Peptidase_M28 PF04389.12 AEO70028.1 - 3.9e-39 134.2 0.0 5.2e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 DUF3270 PF11674.3 AEO70028.1 - 0.13 12.3 0.2 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) Pol_alpha_B_N PF08418.5 AEO70029.1 - 0.3 10.5 5.0 0.48 9.9 3.5 1.4 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF3245 PF11595.3 AEO70029.1 - 0.56 10.4 5.1 0.15 12.3 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) ABC_tran PF00005.22 AEO70031.1 - 1.6e-33 115.8 0.0 3.3e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 AEO70031.1 - 1.8e-13 50.5 9.5 1.8e-13 50.5 6.6 2.4 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.14 AEO70031.1 - 2.2e-06 27.0 0.0 3.7e-05 23.0 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AEO70031.1 - 5.1e-06 26.6 0.0 0.0074 16.2 0.0 2.4 1 1 1 2 2 2 2 AAA domain DUF258 PF03193.11 AEO70031.1 - 0.00081 18.6 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 AEO70031.1 - 0.0023 18.7 0.0 0.0053 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AEO70031.1 - 0.0085 15.2 0.1 0.029 13.4 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin SbcCD_C PF13558.1 AEO70031.1 - 0.012 15.4 0.2 0.094 12.6 0.1 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 AEO70031.1 - 0.017 15.4 1.2 0.026 14.8 0.1 1.8 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.1 AEO70031.1 - 0.018 14.5 0.1 0.048 13.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PBP1_TM PF14812.1 AEO70031.1 - 0.02 15.2 1.4 0.71 10.2 0.4 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF815 PF05673.8 AEO70031.1 - 0.04 12.8 0.0 0.071 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 AEO70031.1 - 0.06 13.3 0.4 0.42 10.5 0.3 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 AEO70031.1 - 0.1 12.9 0.1 0.42 10.9 0.0 2.1 3 0 0 3 3 2 0 AAA domain CDC45 PF02724.9 AEO70031.1 - 1.2 7.0 9.8 1.9 6.3 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1768 PF08719.6 AEO70032.1 - 6.1e-53 178.7 0.0 8.2e-53 178.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Tim44 PF04280.10 AEO70033.1 - 8.6e-34 116.6 0.0 2.3e-33 115.2 0.0 1.8 1 0 0 1 1 1 1 Tim44-like domain Ribosomal_S11 PF00411.14 AEO70034.1 - 1.6e-11 44.3 0.1 2.6e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 DUF484 PF04340.7 AEO70034.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF484 BCS1_N PF08740.6 AEO70035.1 - 1.2e-45 155.4 0.0 1.7e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 AEO70035.1 - 3.7e-20 72.4 0.0 6e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AEO70035.1 - 1.5e-05 24.1 0.0 2.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 AEO70035.1 - 3e-05 24.8 0.0 0.0001 23.0 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 AEO70035.1 - 5.6e-05 23.2 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO70035.1 - 6.2e-05 22.7 0.0 0.00015 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AEO70035.1 - 0.00017 21.6 0.0 0.00051 20.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 AEO70035.1 - 0.0002 20.8 0.0 0.00083 18.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AEO70035.1 - 0.0011 18.7 0.3 0.018 14.7 0.2 2.9 1 1 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 AEO70035.1 - 0.002 17.9 0.0 0.0099 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 AEO70035.1 - 0.0042 16.0 0.0 0.0067 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 AEO70035.1 - 0.0057 16.2 0.0 0.0091 15.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 AEO70035.1 - 0.0088 15.6 0.4 0.028 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AEO70035.1 - 0.011 15.9 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AEO70035.1 - 0.021 14.7 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 AEO70035.1 - 0.024 14.0 0.0 0.055 12.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 AEO70035.1 - 0.028 14.6 0.0 0.067 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.10 AEO70035.1 - 0.028 13.1 0.0 0.041 12.5 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein KaiC PF06745.8 AEO70035.1 - 0.033 13.3 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.22 AEO70035.1 - 0.037 14.3 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 AEO70035.1 - 0.039 13.0 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_21 PF13304.1 AEO70035.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AEO70035.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 AEO70035.1 - 0.079 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_3 PF07726.6 AEO70035.1 - 0.088 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 AEO70035.1 - 0.11 12.2 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 AEO70035.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Mago-bind PF09282.5 AEO70036.1 - 2.9e-15 55.5 3.4 6.4e-15 54.3 2.4 1.6 1 0 0 1 1 1 1 Mago binding PV-1 PF06637.6 AEO70036.1 - 0.13 10.7 6.0 0.18 10.3 4.2 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) RR_TM4-6 PF06459.7 AEO70036.1 - 0.18 11.6 11.5 0.24 11.2 8.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UCR_UQCRX_QCR9 PF05365.7 AEO70037.1 - 1.2e-24 85.6 2.3 1.6e-24 85.2 1.6 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-UBR PF02207.15 AEO70038.1 - 1.4e-18 66.3 15.7 3.5e-18 65.0 10.9 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 AEO70038.1 - 0.00019 21.1 0.0 0.00056 19.5 0.0 1.8 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS zf-C3HC4_2 PF13923.1 AEO70038.1 - 0.007 16.3 0.6 0.007 16.3 0.4 3.8 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) CAP_N PF01213.14 AEO70038.1 - 2.7 7.1 3.9 5.4 6.2 2.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.20 AEO70039.1 - 1e-53 182.1 0.0 4e-35 121.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO70039.1 - 4.5e-26 91.4 0.0 1.8e-18 66.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF1851 PF08906.6 AEO70039.1 - 0.067 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1851) Kinase-like PF14531.1 AEO70039.1 - 0.081 11.8 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like FKBP_C PF00254.23 AEO70040.1 - 2.4e-32 110.8 0.0 5.5e-31 106.4 0.0 2.4 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4614 PF15391.1 AEO70040.1 - 1.8 8.2 6.7 0.34 10.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) DUF4066 PF13278.1 AEO70041.1 - 2.6e-12 46.3 0.0 3.7e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 AEO70041.1 - 6.5e-06 25.6 0.0 8.2e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Pox_Ag35 PF03286.9 AEO70043.1 - 0.0047 16.4 8.7 0.0068 15.9 6.0 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein PBP_sp32 PF07222.7 AEO70043.1 - 0.056 12.6 4.0 0.074 12.2 2.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF3246 PF11596.3 AEO70043.1 - 0.058 12.6 0.3 0.068 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Glypican PF01153.14 AEO70043.1 - 0.068 11.7 0.7 0.082 11.5 0.5 1.1 1 0 0 1 1 1 0 Glypican Na_trans_assoc PF06512.8 AEO70043.1 - 0.09 12.7 3.1 0.1 12.5 2.2 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated PBP1_TM PF14812.1 AEO70043.1 - 0.1 12.9 22.6 0.094 13.0 3.3 2.3 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 AEO70043.1 - 0.16 9.8 13.4 0.19 9.6 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 AEO70043.1 - 0.24 10.3 12.9 0.32 9.9 8.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TFIIF_alpha PF05793.7 AEO70043.1 - 0.29 9.4 17.6 0.37 9.1 12.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PGA2 PF07543.7 AEO70043.1 - 0.45 10.3 12.0 0.75 9.5 8.3 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF2201_N PF13203.1 AEO70043.1 - 0.83 8.7 6.2 1.2 8.2 4.3 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain Tom22 PF04281.8 AEO70043.1 - 0.91 9.0 6.6 0.28 10.6 0.7 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Daxx PF03344.10 AEO70043.1 - 0.94 7.8 10.1 1.3 7.3 7.0 1.3 1 0 0 1 1 1 0 Daxx Family AF1Q PF15017.1 AEO70043.1 - 1 9.3 8.6 9.5 6.2 0.1 2.2 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator RNase_H2_suC PF08615.6 AEO70043.1 - 1.1 9.0 5.0 26 4.6 3.5 2.0 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) eIF3_subunit PF08597.5 AEO70043.1 - 1.7 8.1 19.9 2.4 7.6 13.8 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1510 PF07423.6 AEO70043.1 - 2.1 7.6 12.8 2.6 7.3 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2151 PF10221.4 AEO70043.1 - 3.5 5.6 5.9 3.9 5.5 4.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator ANAPC15 PF15243.1 AEO70043.1 - 4.4 7.4 15.1 5.7 7.0 5.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 eIF-3c_N PF05470.7 AEO70043.1 - 5.1 5.0 9.1 6.1 4.8 6.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF3774 PF12609.3 AEO70044.1 - 0.97 10.3 6.9 0.54 11.1 0.2 2.3 2 0 0 2 2 2 0 Wound-induced protein Pox_Ag35 PF03286.9 AEO70045.1 - 0.0047 16.4 8.7 0.0068 15.9 6.0 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein PBP_sp32 PF07222.7 AEO70045.1 - 0.056 12.6 4.0 0.074 12.2 2.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF3246 PF11596.3 AEO70045.1 - 0.058 12.6 0.3 0.068 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Glypican PF01153.14 AEO70045.1 - 0.068 11.7 0.7 0.082 11.5 0.5 1.1 1 0 0 1 1 1 0 Glypican Na_trans_assoc PF06512.8 AEO70045.1 - 0.09 12.7 3.1 0.1 12.5 2.2 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated PBP1_TM PF14812.1 AEO70045.1 - 0.1 12.9 22.6 0.094 13.0 3.3 2.3 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 AEO70045.1 - 0.16 9.8 13.4 0.19 9.6 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 AEO70045.1 - 0.24 10.3 12.9 0.32 9.9 8.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TFIIF_alpha PF05793.7 AEO70045.1 - 0.29 9.4 17.6 0.37 9.1 12.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PGA2 PF07543.7 AEO70045.1 - 0.45 10.3 12.0 0.75 9.5 8.3 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF2201_N PF13203.1 AEO70045.1 - 0.83 8.7 6.2 1.2 8.2 4.3 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain Tom22 PF04281.8 AEO70045.1 - 0.91 9.0 6.6 0.28 10.6 0.7 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Daxx PF03344.10 AEO70045.1 - 0.94 7.8 10.1 1.3 7.3 7.0 1.3 1 0 0 1 1 1 0 Daxx Family AF1Q PF15017.1 AEO70045.1 - 1 9.3 8.6 9.5 6.2 0.1 2.2 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator RNase_H2_suC PF08615.6 AEO70045.1 - 1.1 9.0 5.0 26 4.6 3.5 2.0 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) eIF3_subunit PF08597.5 AEO70045.1 - 1.7 8.1 19.9 2.4 7.6 13.8 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1510 PF07423.6 AEO70045.1 - 2.1 7.6 12.8 2.6 7.3 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2151 PF10221.4 AEO70045.1 - 3.5 5.6 5.9 3.9 5.5 4.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator ANAPC15 PF15243.1 AEO70045.1 - 4.4 7.4 15.1 5.7 7.0 5.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 eIF-3c_N PF05470.7 AEO70045.1 - 5.1 5.0 9.1 6.1 4.8 6.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Glyco_trans_2_3 PF13632.1 AEO70046.1 - 2.9e-17 63.0 1.2 2.9e-17 63.0 0.8 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 THF_DHG_CYH_C PF02882.14 AEO70046.1 - 0.034 13.2 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FimP PF09766.4 AEO70047.1 - 1.2e-27 96.9 10.1 1.5e-27 96.5 7.0 1.1 1 0 0 1 1 1 1 Fms-interacting protein TSC22 PF01166.13 AEO70047.1 - 0.028 14.3 5.8 0.32 10.9 0.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.10 AEO70047.1 - 0.35 10.3 6.5 3.4 7.2 3.2 2.6 2 0 0 2 2 2 0 Septum formation initiator Phasin_2 PF09361.5 AEO70047.1 - 0.39 10.7 4.8 0.47 10.5 0.6 2.4 2 0 0 2 2 2 0 Phasin protein DUF4200 PF13863.1 AEO70047.1 - 0.87 9.5 13.9 2.2 8.2 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF972 PF06156.8 AEO70047.1 - 2.3 8.5 8.0 10 6.5 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) NinG PF05766.7 AEO70047.1 - 3.2 7.4 5.9 2.2 7.9 1.6 2.0 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein PP28 PF10252.4 AEO70047.1 - 6.3 6.9 12.8 1.2 9.2 4.2 2.7 3 0 0 3 3 3 0 Casein kinase substrate phosphoprotein PP28 HlyIII PF03006.15 AEO70048.1 - 1.1e-58 198.2 22.4 1.3e-58 197.9 15.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related RabGAP-TBC PF00566.13 AEO70049.1 - 2.1e-33 115.6 0.5 3.4e-27 95.3 0.0 2.5 3 0 0 3 3 3 2 Rab-GTPase-TBC domain PAT1 PF09770.4 AEO70049.1 - 1.3 7.2 25.8 1.7 6.7 17.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sulfate_transp PF00916.15 AEO70050.1 - 8.1e-72 241.5 11.3 1.5e-71 240.6 7.8 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 AEO70050.1 - 3.3e-30 103.5 2.7 3.3e-30 103.5 1.9 3.0 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 AEO70050.1 - 1.1e-07 31.2 0.0 2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 AEO70050.1 - 0.67 9.7 10.2 0.089 12.4 0.7 3.6 3 0 0 3 3 3 0 Stannin transmembrane Exo_endo_phos PF03372.18 AEO70051.1 - 2.3e-20 73.5 0.0 3.5e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Luciferase_cat PF10285.4 AEO70051.1 - 0.028 13.6 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain WD40 PF00400.27 AEO70052.1 - 6.6e-55 181.1 21.8 1.8e-11 43.4 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 AEO70052.1 - 8.1e-07 27.5 2.7 0.014 13.5 0.1 3.6 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AEO70052.1 - 0.00041 19.2 0.5 0.13 10.9 0.1 2.8 2 1 1 3 3 3 2 Nup133 N terminal like Apc4_WD40 PF12894.2 AEO70052.1 - 0.084 12.3 0.0 5.3 6.6 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3312 PF11768.3 AEO70052.1 - 0.22 9.7 0.0 2 6.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Pcc1 PF09341.5 AEO70053.1 - 2e-24 85.4 2.7 2.5e-24 85.1 1.8 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.1 AEO70054.1 - 5.4e-44 149.6 0.0 7.7e-41 139.3 0.0 3.2 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 AEO70054.1 - 3e-17 62.4 0.0 5.9e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AEO70054.1 - 5.7e-07 29.1 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 AEO70054.1 - 0.017 15.1 0.0 0.043 13.8 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 AEO70054.1 - 0.051 13.8 0.1 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 AEO70054.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family SWIM PF04434.12 AEO70055.1 - 0.056 12.9 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 SWIM zinc finger Pkinase PF00069.20 AEO70056.1 - 1e-06 28.1 0.0 2.9e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO70056.1 - 0.00066 18.8 0.0 0.0031 16.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Poty_coat PF00767.13 AEO70056.1 - 0.24 10.6 0.0 0.44 9.7 0.0 1.3 1 0 0 1 1 1 0 Potyvirus coat protein Zn_clus PF00172.13 AEO70057.1 - 0.0021 17.9 5.5 0.0044 16.9 3.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 AEO70059.1 - 5.6e-23 81.9 0.1 7.4e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 AEO70059.1 - 0.029 13.2 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 CsiD Pro-rich_19 PF15455.1 AEO70059.1 - 0.13 11.2 0.4 0.3 10.0 0.0 1.8 2 0 0 2 2 2 0 Proline-rich 19 7tm_2 PF00002.19 AEO70061.1 - 0.00016 20.8 11.6 0.00029 20.0 8.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 AEO70061.1 - 0.0016 17.4 5.0 0.0027 16.6 3.5 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor VirB8 PF04335.8 AEO70061.1 - 0.053 13.1 4.8 0.063 12.8 0.2 2.3 2 0 0 2 2 2 0 VirB8 protein Vma12 PF11712.3 AEO70061.1 - 4.7 6.9 8.7 12 5.5 1.8 3.2 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Cellulase PF00150.13 AEO70062.1 - 6.5e-40 137.1 0.1 7.6e-40 136.8 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) OppC_N PF12911.2 AEO70062.1 - 0.079 12.3 1.2 11 5.4 0.0 2.8 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C CRT10 PF08728.5 AEO70063.1 - 2.3e-16 59.0 0.0 1e-12 46.9 0.0 2.1 2 0 0 2 2 2 2 CRT10 Ammonium_transp PF00909.16 AEO70064.1 - 3.9e-114 381.2 28.0 4.5e-114 381.0 19.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF2207 PF09972.4 AEO70064.1 - 4 5.9 4.6 9.7 4.6 0.4 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Abhydrolase_6 PF12697.2 AEO70065.1 - 9.3e-25 87.8 5.8 1.8e-24 86.9 4.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO70065.1 - 1.3e-12 47.7 0.1 6.6e-12 45.4 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO70065.1 - 4e-08 33.1 0.0 1.2e-07 31.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 AEO70065.1 - 4.4e-05 23.2 0.0 8.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 AEO70065.1 - 0.018 14.6 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.7 AEO70065.1 - 0.051 13.2 0.0 0.92 9.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF676 PF05057.9 AEO70065.1 - 0.072 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DLH PF01738.13 AEO70065.1 - 0.12 11.6 0.0 0.26 10.5 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Gram_pos_anchor PF00746.16 AEO70065.1 - 0.14 11.9 1.5 0.38 10.6 1.0 1.7 1 0 0 1 1 1 0 Gram positive anchor Oxysterol_BP PF01237.13 AEO70066.1 - 2.3e-92 309.2 0.0 2.9e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein zf-CCCH PF00642.19 AEO70068.1 - 1.1e-08 34.5 17.3 3.2e-07 29.8 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 AEO70068.1 - 0.00027 20.7 0.0 0.00048 19.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO70068.1 - 0.0055 16.3 0.0 0.009 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SCRG1 PF15224.1 AEO70068.1 - 0.78 9.5 5.0 0.61 9.9 0.2 2.4 2 0 0 2 2 2 0 Scrapie-responsive protein 1 C2 PF00168.25 AEO70069.1 - 2.5e-74 245.1 3.9 1.8e-20 72.5 0.1 5.5 5 0 0 5 5 5 5 C2 domain NT-C2 PF10358.4 AEO70069.1 - 0.035 13.5 0.1 0.1 12.0 0.0 1.8 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins DUF2404 PF10296.4 AEO70069.1 - 0.16 12.1 0.0 0.69 10.0 0.0 2.2 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) B56 PF01603.15 AEO70069.1 - 0.19 10.3 0.1 0.32 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) ELMO_CED12 PF04727.8 AEO70070.1 - 1.4e-50 171.1 0.0 2.4e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 AEO70070.1 - 0.0026 17.4 0.0 0.39 10.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) zf-GRF PF06839.7 AEO70071.1 - 1.3e-08 34.5 4.5 2.2e-08 33.8 3.1 1.4 1 0 0 1 1 1 1 GRF zinc finger Striatin PF08232.7 AEO70071.1 - 0.0076 16.5 2.4 0.0076 16.5 1.7 2.4 2 0 0 2 2 2 1 Striatin family ATP-synt_D PF01813.12 AEO70071.1 - 0.026 14.0 1.3 0.04 13.4 0.9 1.3 1 0 0 1 1 1 0 ATP synthase subunit D FUSC PF04632.7 AEO70071.1 - 3.7 5.8 5.1 5.5 5.2 3.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Homeobox PF00046.24 AEO70072.1 - 3.7e-15 55.2 6.8 1e-14 53.9 4.7 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 AEO70072.1 - 0.047 13.4 0.5 0.16 11.6 0.3 1.9 1 0 0 1 1 1 0 Homeobox KN domain NAD_kinase PF01513.16 AEO70073.1 - 1.9e-72 243.4 0.0 2.5e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.16 AEO70074.1 - 3.4e-13 50.0 0.0 5e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PBP-Tp47_a PF14889.1 AEO70074.1 - 0.095 12.0 0.0 0.46 9.7 0.0 1.9 2 0 0 2 2 2 0 Penicillin-binding protein Tp47 domain a PTPA PF03095.10 AEO70075.1 - 5.8e-115 383.5 0.0 6.9e-115 383.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF4632 PF15451.1 AEO70075.1 - 3.2 7.7 6.3 0.51 10.3 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4632) R3H PF01424.17 AEO70077.1 - 1.4e-14 53.4 0.1 3e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 AEO70077.1 - 3.4e-06 26.8 60.1 2.2e-05 24.3 12.3 13.0 12 2 0 12 12 12 7 NF-X1 type zinc finger Abhydrolase_5 PF12695.2 AEO70078.1 - 6.9e-24 84.2 0.0 1.1e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO70078.1 - 1.5e-19 70.7 0.0 2.3e-18 66.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO70078.1 - 1.2e-08 34.7 0.1 0.00055 19.5 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 AEO70078.1 - 7.1e-06 24.7 0.1 0.4 9.1 0.0 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) DUF818 PF05677.7 AEO70078.1 - 0.00012 20.9 0.0 0.00018 20.3 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.8 AEO70078.1 - 0.00015 21.3 0.0 0.00054 19.4 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 AEO70078.1 - 0.00035 20.0 0.0 0.082 12.3 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 AEO70078.1 - 0.0053 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 AEO70078.1 - 0.0074 15.8 0.0 0.017 14.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 AEO70078.1 - 0.0088 15.7 0.0 0.067 12.8 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 AEO70078.1 - 0.01 15.1 0.0 0.94 8.7 0.0 2.6 3 0 0 3 3 3 0 Dienelactone hydrolase family Peptidase_S9 PF00326.16 AEO70078.1 - 0.013 14.7 0.0 0.1 11.7 0.0 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 AEO70078.1 - 0.044 13.2 0.0 8.1 5.7 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1749 PF08538.5 AEO70078.1 - 0.16 10.8 0.0 0.45 9.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) zf-LYAR PF08790.6 AEO70079.1 - 2.6e-14 52.6 2.4 6.1e-14 51.4 1.7 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger 3-PAP PF12578.3 AEO70079.1 - 3.2 7.6 6.0 1.7 8.4 1.8 2.1 2 0 0 2 2 2 0 Myotubularin-associated protein Pex2_Pex12 PF04757.9 AEO70080.1 - 1.9e-43 148.5 0.4 2.5e-43 148.1 0.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 AEO70080.1 - 9.3e-12 44.5 8.1 1.4e-11 44.0 5.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO70080.1 - 1.5e-11 44.1 7.4 2.2e-11 43.5 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO70080.1 - 1e-09 37.8 6.4 1.5e-09 37.3 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO70080.1 - 1.2e-09 37.7 6.3 1.8e-09 37.1 4.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO70080.1 - 1.9e-08 33.8 5.6 2.9e-08 33.3 3.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AEO70080.1 - 6.2e-07 29.1 7.4 9.7e-07 28.5 5.1 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 AEO70080.1 - 3.1e-05 23.6 2.5 6.2e-05 22.7 1.7 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 AEO70080.1 - 0.0001 22.3 7.4 0.00026 21.0 5.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 AEO70080.1 - 0.0009 18.9 4.5 0.0017 17.9 3.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 AEO70080.1 - 0.007 15.8 1.1 0.011 15.1 0.8 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 AEO70080.1 - 0.14 11.7 8.3 0.26 10.9 5.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TerY-C PF15616.1 AEO70080.1 - 0.14 12.0 2.8 0.25 11.2 1.9 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zf-Apc11 PF12861.2 AEO70080.1 - 0.19 11.5 4.0 0.41 10.5 2.8 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger IBR PF01485.16 AEO70080.1 - 2.3 8.1 6.9 6.3 6.7 4.8 1.6 1 1 0 1 1 1 0 IBR domain EXS PF03124.9 AEO70081.1 - 1.4e-99 333.3 3.2 1.6e-99 333.2 2.2 1.0 1 0 0 1 1 1 1 EXS family NUDIX PF00293.23 AEO70083.1 - 2e-12 46.9 0.1 4.8e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain SelB-wing_3 PF09107.6 AEO70083.1 - 0.016 14.5 0.2 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Bindin PF02084.10 AEO70083.1 - 0.068 13.2 0.9 0.11 12.4 0.6 1.3 1 0 0 1 1 1 0 Bindin Ctr PF04145.10 AEO70084.1 - 7.9e-14 51.9 0.1 9.8e-14 51.6 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Cas_Csy2 PF09614.5 AEO70084.1 - 0.071 12.3 0.0 0.071 12.3 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) 3-HAO PF06052.7 AEO70085.1 - 5.3e-63 210.9 0.0 6e-63 210.7 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 AEO70085.1 - 6.8e-06 25.4 0.0 1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 AEO70085.1 - 0.00053 19.6 0.0 0.00094 18.8 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 AEO70085.1 - 0.004 16.5 0.0 0.006 16.0 0.0 1.2 1 0 0 1 1 1 1 Cupin GPI PF06560.6 AEO70085.1 - 0.084 11.8 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) DZR PF12773.2 AEO70085.1 - 0.38 10.6 3.4 0.82 9.5 2.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon IBR PF01485.16 AEO70085.1 - 6 6.8 6.8 9.5 6.1 2.8 2.5 2 1 0 2 2 2 0 IBR domain bZIP_2 PF07716.10 AEO70086.1 - 5.7 6.8 8.3 0.42 10.4 2.3 1.7 2 0 0 2 2 2 0 Basic region leucine zipper PWI PF01480.12 AEO70087.1 - 3e-30 104.1 0.0 4.1e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 PWI domain NuA4 PF09340.5 AEO70088.1 - 5e-25 86.9 0.1 8e-25 86.3 0.0 1.3 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Med3 PF11593.3 AEO70088.1 - 0.29 10.3 14.9 0.35 10.0 10.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peptidase_S9 PF00326.16 AEO70089.1 - 5.6e-53 179.3 0.0 9.4e-53 178.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO70089.1 - 7.3e-11 42.0 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO70089.1 - 9.7e-10 38.7 0.4 1.9e-09 37.7 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 AEO70089.1 - 0.003 17.1 1.1 0.1 12.2 0.0 3.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat AXE1 PF05448.7 AEO70089.1 - 0.042 12.3 0.0 0.1 11.0 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Rad21_Rec8_N PF04825.8 AEO70090.1 - 5.9e-35 119.5 0.0 1e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 AEO70090.1 - 7.8e-08 31.3 1.3 9.8e-08 31.0 0.1 1.8 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 AEO70090.1 - 0.0002 21.0 0.1 0.042 13.4 0.0 2.3 2 0 0 2 2 2 2 ScpA/B protein E1-E2_ATPase PF00122.15 AEO70091.1 - 8.1e-73 244.2 0.0 1.4e-72 243.4 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AEO70091.1 - 1.1e-45 155.4 0.1 1.1e-45 155.4 0.0 1.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AEO70091.1 - 9.8e-27 94.7 0.0 1.5e-25 90.9 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AEO70091.1 - 1.8e-21 75.3 0.0 3.5e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 AEO70091.1 - 2.5e-13 49.7 0.0 4.8e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AEO70091.1 - 2.9e-13 50.4 0.0 1.2e-12 48.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AEO70091.1 - 4.7e-05 23.1 1.7 8.7e-05 22.2 1.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Dynamin_N PF00350.18 AEO70092.1 - 9.6e-30 103.6 0.0 2e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 AEO70092.1 - 1.8e-11 43.3 0.0 2.9e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Miro PF08477.8 AEO70092.1 - 0.0018 18.7 0.0 0.0039 17.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AEO70092.1 - 0.0038 17.1 0.0 0.055 13.4 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 AEO70092.1 - 0.0093 15.8 0.3 0.1 12.5 0.2 2.5 1 1 0 1 1 1 1 Dynamin GTPase effector domain AAA_21 PF13304.1 AEO70092.1 - 0.038 13.9 0.0 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 AEO70092.1 - 0.092 13.0 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter COG4 PF08318.7 AEO70093.1 - 7.3e-94 314.2 0.0 1e-93 313.7 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein ThiS PF02597.15 AEO70094.1 - 2.5e-07 31.0 0.1 5e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 ThiS family Dynamitin PF04912.9 AEO70095.1 - 2.1e-34 118.9 8.3 3.9e-17 62.1 0.1 2.9 2 1 0 2 2 2 2 Dynamitin FH2 PF02181.18 AEO70095.1 - 0.00032 19.6 7.1 0.16 10.8 0.2 3.1 3 0 0 3 3 3 2 Formin Homology 2 Domain Laminin_II PF06009.7 AEO70095.1 - 0.026 14.2 1.0 0.026 14.2 0.7 4.1 3 2 2 5 5 5 0 Laminin Domain II DivIC PF04977.10 AEO70095.1 - 0.027 13.9 0.9 0.027 13.9 0.6 3.4 3 0 0 3 3 3 0 Septum formation initiator DUF1515 PF07439.6 AEO70095.1 - 0.069 12.9 7.8 0.086 12.6 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) CENP-F_leu_zip PF10473.4 AEO70095.1 - 0.11 12.4 14.0 0.13 12.0 1.0 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CorA PF01544.13 AEO70095.1 - 0.17 10.9 8.2 0.094 11.7 2.1 2.6 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein DUF4337 PF14235.1 AEO70095.1 - 1.2 8.9 12.5 11 5.8 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) TBCA PF02970.11 AEO70095.1 - 1.3 9.1 13.6 0.97 9.5 1.5 3.2 3 0 0 3 3 3 0 Tubulin binding cofactor A APG6 PF04111.7 AEO70095.1 - 2.7 6.9 12.0 1.5 7.7 0.5 3.1 3 0 0 3 3 3 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 AEO70095.1 - 2.7 7.7 18.4 0.27 10.9 1.6 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.15 AEO70095.1 - 3.3 7.5 13.8 1.7 8.4 0.5 4.3 3 1 1 4 4 4 0 Prefoldin subunit TBPIP PF07106.8 AEO70095.1 - 3.4 7.1 8.6 3.1 7.3 0.4 3.1 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 AEO70095.1 - 3.9 6.6 8.3 7.2 5.7 0.2 3.1 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Dor1 PF04124.7 AEO70095.1 - 4.6 5.6 6.8 14 4.0 0.1 3.1 3 0 0 3 3 3 0 Dor1-like family Mnd1 PF03962.10 AEO70095.1 - 6.3 6.4 14.2 1.1 8.8 0.7 3.0 3 0 0 3 3 3 0 Mnd1 family DUF1192 PF06698.6 AEO70095.1 - 9.3 6.1 21.0 0.39 10.5 1.7 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) RTC4 PF14474.1 AEO70096.1 - 2.4e-34 117.9 0.0 3.7e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain Auxin_repressed PF05564.7 AEO70097.1 - 0.039 14.5 1.8 0.043 14.4 1.2 1.1 1 0 0 1 1 1 0 Dormancy/auxin associated protein PP2C PF00481.16 AEO70098.1 - 2.9e-61 207.0 0.0 4.7e-61 206.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 AEO70098.1 - 3.1e-50 167.0 57.6 1.6e-07 30.7 0.4 12.9 5 5 5 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO70098.1 - 1.7e-42 142.9 60.8 4.1e-11 42.4 0.9 10.6 7 4 5 12 12 11 9 Leucine rich repeat Guanylate_cyc PF00211.15 AEO70098.1 - 4.7e-27 94.5 0.0 1.1e-26 93.3 0.0 1.5 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 AEO70098.1 - 3.6e-25 84.1 52.3 0.06 13.3 0.0 19.8 20 1 0 20 20 20 8 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 AEO70098.1 - 4.1e-19 67.6 1.5 9.3e-19 66.5 1.0 1.7 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain RA PF00788.18 AEO70098.1 - 1.5e-09 38.2 0.0 4.1e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 AEO70098.1 - 1.1e-07 30.8 62.0 0.043 13.9 0.1 17.1 19 0 0 19 19 18 3 Leucine rich repeat LRR_6 PF13516.1 AEO70098.1 - 0.00011 21.9 45.4 5 7.5 0.0 15.4 18 0 0 18 18 17 2 Leucine Rich repeat PP2C_2 PF13672.1 AEO70098.1 - 0.0044 16.4 0.0 0.0085 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Baculo_PEP_N PF04512.7 AEO70098.1 - 0.065 13.2 0.0 45 4.1 0.0 3.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, N terminus LRR_9 PF14580.1 AEO70098.1 - 0.079 12.5 11.0 4.8 6.7 0.0 4.4 2 1 2 4 4 4 0 Leucine-rich repeat ABC_membrane_2 PF06472.10 AEO70099.1 - 7.6e-87 291.0 0.0 1.4e-86 290.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 AEO70099.1 - 9.3e-16 58.3 0.0 3.2e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 AEO70099.1 - 0.0015 18.5 0.0 0.048 13.6 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AEO70099.1 - 0.0059 17.4 0.1 0.061 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AEO70099.1 - 0.027 14.4 0.2 0.092 12.7 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain RuvB_N PF05496.7 AEO70099.1 - 0.033 13.2 0.0 0.097 11.6 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 AEO70099.1 - 0.037 13.1 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 AEO70099.1 - 0.044 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 AEO70099.1 - 0.046 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 AEO70099.1 - 0.079 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 AEO70099.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NIF PF03031.13 AEO70100.1 - 3.6e-51 172.9 0.2 4.8e-51 172.5 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sec61_beta PF03911.11 AEO70101.1 - 8.3e-21 73.5 1.5 1.1e-20 73.1 1.0 1.1 1 0 0 1 1 1 1 Sec61beta family DUF1180 PF06679.7 AEO70101.1 - 2.6 7.8 8.6 4.3 7.2 6.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) UCH PF00443.24 AEO70102.1 - 2.6e-50 171.0 0.0 2.6e-50 171.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO70102.1 - 2.1e-23 83.2 0.3 6.8e-23 81.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF4407 PF14362.1 AEO70102.1 - 0.19 10.6 8.4 0.47 9.3 5.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4192 PF13830.1 AEO70102.1 - 0.42 10.2 11.3 1 8.9 7.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Ycf1 PF05758.7 AEO70102.1 - 4.2 4.9 7.7 6 4.4 5.3 1.3 1 0 0 1 1 1 0 Ycf1 DUF3138 PF11336.3 AEO70102.1 - 8.8 4.3 7.4 17 3.4 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Yos1 PF08571.5 AEO70103.1 - 6.7e-29 99.8 0.9 7.4e-29 99.6 0.6 1.0 1 0 0 1 1 1 1 Yos1-like Aldo_ket_red PF00248.16 AEO70105.1 - 3e-48 164.0 0.0 3.4e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.2 AEO70106.1 - 1.4e-42 142.6 25.1 7.6e-11 41.3 0.1 6.6 4 1 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO70106.1 - 3.3e-30 103.6 46.5 1.9e-08 33.9 3.5 5.2 1 1 7 8 8 8 7 Leucine rich repeat LRR_7 PF13504.1 AEO70106.1 - 2.6e-12 44.8 15.8 2 8.9 0.0 9.0 8 0 0 8 8 8 4 Leucine rich repeat LRR_9 PF14580.1 AEO70106.1 - 4e-10 39.5 8.9 0.00047 19.7 1.8 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.28 AEO70106.1 - 2.2e-09 36.0 28.1 0.1 12.6 0.3 10.9 12 0 0 12 12 12 2 Leucine Rich Repeat LRR_6 PF13516.1 AEO70106.1 - 5.4e-09 35.2 20.9 0.34 11.1 0.1 9.5 7 4 3 10 10 10 4 Leucine Rich repeat Abhydrolase_5 PF12695.2 AEO70107.1 - 3.1e-08 33.4 0.0 4.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO70107.1 - 8.3e-06 25.8 0.3 3.5e-05 23.8 0.1 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family BTB PF00651.26 AEO70108.1 - 2.6e-10 40.2 0.1 9.1e-10 38.5 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.10 AEO70108.1 - 0.00084 19.3 0.0 0.035 14.1 0.0 2.3 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain PCI PF01399.22 AEO70110.1 - 2.7e-12 46.9 0.0 7.4e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 PCI domain Ribosomal_L18ae PF01775.12 AEO70111.1 - 2.2e-59 198.7 0.4 2.8e-59 198.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Acetyltransf_3 PF13302.1 AEO70112.1 - 1.8e-15 57.3 0.0 2.1e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AEO70112.1 - 0.018 14.8 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SinI PF08671.5 AEO70114.1 - 0.021 14.2 1.0 0.1 12.0 0.7 2.2 1 0 0 1 1 1 0 Anti-repressor SinI Ribosomal_60s PF00428.14 AEO70114.1 - 0.051 13.9 5.0 0.096 13.1 3.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF1656 PF07869.7 AEO70114.1 - 0.18 11.6 1.5 0.3 10.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) ATP-synt_E PF05680.7 AEO70115.1 - 3.5e-27 94.1 0.1 3.6e-27 94.1 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain DUF349 PF03993.7 AEO70115.1 - 0.011 15.9 0.2 0.015 15.4 0.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) ABC_trans_N PF14510.1 AEO70115.1 - 0.054 13.5 0.1 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal WD40 PF00400.27 AEO70116.1 - 6.8e-22 76.4 2.7 2.8e-07 30.1 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Dynein_IC2 PF11540.3 AEO70116.1 - 0.15 11.4 0.6 2.9 7.3 0.6 2.4 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 MRP-L46 PF11788.3 AEO70116.1 - 4.8 7.8 7.6 0.42 11.3 1.6 2.0 2 1 0 2 2 2 0 39S mitochondrial ribosomal protein L46 Aldo_ket_red PF00248.16 AEO70117.1 - 4e-58 196.4 0.0 4.5e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Flag1_repress PF03614.8 AEO70118.1 - 0.14 11.7 0.1 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Repressor of phase-1 flagellin MaoC_dehydratas PF01575.14 AEO70119.1 - 6.2e-23 80.5 0.0 1.1e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 AEO70119.1 - 2e-07 30.8 0.0 9.1e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase CAP_GLY PF01302.20 AEO70120.1 - 1.6e-19 69.3 0.0 3e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 AEO70120.1 - 1.8e-18 65.7 1.7 0.00019 20.9 0.0 5.3 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO70120.1 - 3.1e-10 39.6 1.3 0.00027 20.6 0.1 4.3 3 1 2 5 5 5 4 Leucine rich repeat LRR_6 PF13516.1 AEO70120.1 - 2.6e-07 30.0 0.8 5.2 7.4 0.0 6.3 6 1 1 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.28 AEO70120.1 - 2.6e-07 29.7 5.6 1.1 9.5 0.0 6.8 6 2 1 7 7 7 1 Leucine Rich Repeat LRR_9 PF14580.1 AEO70120.1 - 5e-06 26.1 0.0 0.00022 20.8 0.0 2.8 3 1 0 3 3 3 1 Leucine-rich repeat LRR_7 PF13504.1 AEO70120.1 - 0.0006 19.5 5.1 28 5.4 0.0 6.3 7 0 0 7 7 7 0 Leucine rich repeat TFIIA PF03153.8 AEO70121.1 - 7 6.4 10.2 11 5.8 7.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PI-PLC-X PF00388.14 AEO70123.1 - 1.1e-05 24.8 0.0 1.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain RNA_pol_Rpb1_6 PF04992.9 AEO70124.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 GPI-anchored PF10342.4 AEO70125.1 - 1.2e-17 64.0 0.0 1.2e-17 64.0 0.0 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Serglycin PF04360.7 AEO70125.1 - 0.0011 18.7 1.1 0.0021 17.8 0.8 1.5 1 0 0 1 1 1 1 Serglycin Tubulin PF00091.20 AEO70126.1 - 9.1e-65 218.4 0.0 1.2e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AEO70126.1 - 5.3e-43 146.0 0.0 8.6e-43 145.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 AEO70126.1 - 7.2e-05 22.3 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF3291 PF11695.3 AEO70126.1 - 0.15 11.4 0.1 18 4.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3291) RRM_1 PF00076.17 AEO70127.1 - 2e-12 46.5 0.0 1.3e-08 34.3 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO70127.1 - 2.7e-11 43.1 0.0 2.3e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO70127.1 - 1.5e-08 34.4 0.1 6.3e-05 22.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.6 AEO70128.1 - 1.5e-28 99.7 2.7 1.5e-28 99.7 1.9 3.4 2 2 0 2 2 2 1 Sds3-like Coiled-coil_56 PF09813.4 AEO70129.1 - 0.00031 20.6 0.0 0.00032 20.6 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.3 AEO70130.1 - 3e-71 239.6 0.0 5.1e-71 238.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) MFS_1 PF07690.11 AEO70133.1 - 3e-20 72.2 38.0 1.4e-12 47.0 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO70133.1 - 2.1e-16 59.5 20.8 4.8e-16 58.3 14.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1772 PF08592.6 AEO70135.1 - 4.8e-22 78.1 6.5 6.7e-22 77.7 4.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Pyr_redox_2 PF07992.9 AEO70137.1 - 1.6e-28 99.9 0.0 2.5e-28 99.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO70137.1 - 1.6e-19 70.0 2.5 2.5e-17 63.0 0.5 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO70137.1 - 6.6e-13 49.1 0.1 7.2e-09 35.9 0.0 3.2 2 2 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 AEO70137.1 - 1.8e-06 28.1 0.0 0.0024 18.1 0.0 2.7 2 2 0 2 2 2 2 Putative NAD(P)-binding DAO PF01266.19 AEO70137.1 - 2.6e-06 26.5 3.8 0.095 11.5 0.0 3.6 2 2 2 4 4 4 3 FAD dependent oxidoreductase Thi4 PF01946.12 AEO70137.1 - 5.9e-05 22.2 1.1 0.001 18.2 0.0 2.5 2 1 1 3 3 3 1 Thi4 family NAD_binding_8 PF13450.1 AEO70137.1 - 0.00011 22.1 0.1 0.05 13.6 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 AEO70137.1 - 0.00089 18.2 0.2 0.21 10.4 0.0 3.4 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 AEO70137.1 - 0.001 18.2 1.2 6.4 5.7 0.0 3.1 2 1 1 3 3 3 2 FAD binding domain Shikimate_DH PF01488.15 AEO70137.1 - 0.0012 18.9 0.3 0.62 10.1 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 AEO70137.1 - 0.0012 17.7 6.7 0.063 12.1 0.2 3.9 2 2 1 4 4 4 1 FAD binding domain GIDA PF01134.17 AEO70137.1 - 0.0039 16.1 5.8 0.54 9.0 0.2 3.9 3 2 0 4 4 4 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 AEO70137.1 - 0.0052 15.9 0.2 0.066 12.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AEO70137.1 - 0.02 13.3 0.4 1.3 7.3 0.1 3.0 2 1 1 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.9 AEO70137.1 - 0.084 11.4 0.1 0.42 9.1 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 AEO70137.1 - 0.092 12.5 0.2 19 5.0 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding ABC_tran PF00005.22 AEO70139.1 - 1e-49 168.3 0.0 2.1e-29 102.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AEO70139.1 - 1.8e-26 93.1 28.9 1.7e-15 57.1 7.0 4.0 4 1 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 AEO70139.1 - 1.4e-09 37.5 0.0 0.00055 19.2 0.0 4.2 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 AEO70139.1 - 5.8e-06 25.8 0.0 0.011 15.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 AEO70139.1 - 0.00019 20.8 0.8 0.61 9.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 AEO70139.1 - 0.00041 19.3 0.0 0.23 10.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.1 AEO70139.1 - 0.00048 20.5 0.1 0.035 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 AEO70139.1 - 0.0028 17.6 1.3 4.5 7.1 0.0 4.0 4 1 1 5 5 5 1 AAA domain AAA_30 PF13604.1 AEO70139.1 - 0.013 15.1 0.3 3.7 7.0 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 AEO70139.1 - 0.013 15.5 7.0 0.053 13.5 0.1 2.9 3 0 0 3 3 3 0 AAA ATPase domain DUF258 PF03193.11 AEO70139.1 - 0.014 14.6 1.8 4.2 6.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF258 Miro PF08477.8 AEO70139.1 - 0.023 15.1 0.2 5.7 7.4 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 AEO70139.1 - 0.024 14.6 0.5 0.44 10.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 AEO70139.1 - 0.032 13.6 0.0 0.8 9.0 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 AEO70139.1 - 0.033 14.3 0.0 23 5.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 AEO70139.1 - 0.037 13.9 0.0 4.8 7.1 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 AEO70139.1 - 0.067 13.0 3.1 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 IstB_IS21 PF01695.12 AEO70139.1 - 0.096 12.0 0.0 7.4 5.9 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.4 AEO70139.1 - 0.14 11.0 0.2 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 AEO70139.1 - 0.16 11.0 0.1 2.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin WD40 PF00400.27 AEO70140.1 - 4.9e-28 95.9 7.4 7.1e-08 32.0 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 AEO70140.1 - 0.0005 19.8 0.1 0.35 10.5 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 AEO70140.1 - 0.0019 17.7 1.1 0.0054 16.2 0.0 2.4 2 0 0 2 2 2 1 HIRA B motif Amidase PF01425.16 AEO70141.1 - 2.7e-83 280.2 0.0 3.3e-83 280.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Methyltransf_31 PF13847.1 AEO70142.1 - 3.8e-15 55.7 0.0 5.4e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO70142.1 - 6.9e-15 55.5 0.1 1.1e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO70142.1 - 1.3e-11 44.8 0.2 5.9e-11 42.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO70142.1 - 1.5e-10 41.1 0.3 2.7e-10 40.3 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO70142.1 - 5.8e-10 39.5 0.0 1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO70142.1 - 1.1e-09 38.1 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 AEO70142.1 - 6.7e-08 32.3 0.1 1e-07 31.7 0.1 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.9 AEO70142.1 - 2.9e-07 30.0 0.0 4.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 AEO70142.1 - 3.1e-07 30.1 0.0 5.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 AEO70142.1 - 1e-06 29.0 0.0 1.5e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 AEO70142.1 - 2.5e-05 23.9 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO70142.1 - 3.7e-05 22.9 0.0 5.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 AEO70142.1 - 6.2e-05 22.2 0.1 0.00011 21.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 AEO70142.1 - 0.00017 20.3 0.0 0.0002 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) RrnaAD PF00398.15 AEO70142.1 - 0.0033 16.4 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.5 AEO70142.1 - 0.021 14.4 0.0 0.064 12.8 0.0 1.7 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.12 AEO70142.1 - 0.037 13.0 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DREV PF05219.7 AEO70142.1 - 0.052 12.4 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase DUF3419 PF11899.3 AEO70142.1 - 0.14 10.8 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Methyltransf_3 PF01596.12 AEO70142.1 - 0.15 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase N6_Mtase PF02384.11 AEO70142.1 - 0.15 11.0 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase DUF1776 PF08643.5 AEO70143.1 - 1.3e-114 382.3 0.0 1.7e-114 381.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) zf-CCCH PF00642.19 AEO70144.1 - 8.2e-19 66.8 33.3 8.8e-07 28.4 0.2 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AEO70144.1 - 0.024 14.6 0.2 0.024 14.6 0.2 5.6 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type E_raikovi_mat PF06360.6 AEO70144.1 - 1.1 9.5 0.1 1.1 9.5 0.0 2.8 3 0 0 3 3 3 0 Euplotes raikovi mating pheromone ADH_zinc_N PF00107.21 AEO70145.1 - 5.9e-36 122.8 0.8 9.7e-36 122.1 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO70145.1 - 1.2e-11 45.5 0.8 2e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO70145.1 - 3.5e-07 29.9 0.0 1.9e-06 27.6 0.0 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 AEO70145.1 - 0.006 16.1 3.3 0.0093 15.5 1.2 1.9 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 AEO70145.1 - 0.027 14.4 0.1 0.05 13.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF1254 PF06863.7 AEO70145.1 - 0.032 14.0 0.1 0.088 12.6 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1254) F-box-like PF12937.2 AEO70146.1 - 3.5e-12 45.8 0.4 6.5e-12 44.9 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO70146.1 - 4.2e-12 45.3 0.2 1.4e-11 43.7 0.1 1.9 1 0 0 1 1 1 1 F-box domain SprT-like PF10263.4 AEO70147.1 - 3.5e-13 49.4 0.0 5.7e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 SprT-like family TraY PF05509.6 AEO70147.1 - 0.11 12.2 0.4 0.2 11.4 0.3 1.4 1 0 0 1 1 1 0 TraY domain Pkinase PF00069.20 AEO70148.1 - 3.5e-60 203.3 0.0 4.4e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO70148.1 - 4e-28 98.2 0.0 5.7e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO70148.1 - 1.2e-07 31.0 0.0 1.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO70148.1 - 9.5e-05 22.2 0.2 0.27 10.9 0.0 2.8 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 AEO70148.1 - 0.0097 14.9 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.21 AEO70149.1 - 2.4e-48 163.1 0.0 2.9e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO70149.1 - 2.9e-05 23.8 0.0 4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AEO70149.1 - 0.00089 19.1 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 AEO70149.1 - 0.0069 16.0 0.1 0.013 15.2 0.0 1.4 1 1 0 1 1 1 1 UEV domain RGS PF00615.14 AEO70150.1 - 7.2e-11 42.2 0.0 8.2e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain PCI PF01399.22 AEO70151.1 - 1.1e-06 28.8 0.0 2.8e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 PCI domain E1-E2_ATPase PF00122.15 AEO70152.1 - 2.2e-55 187.2 0.2 2.2e-55 187.2 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 AEO70152.1 - 1.2e-46 159.8 2.5 3.1e-46 158.5 1.8 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 AEO70152.1 - 2.3e-44 149.3 1.7 2.7e-11 43.4 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 AEO70152.1 - 2.5e-13 50.6 0.0 6.9e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AEO70152.1 - 4.2e-05 23.2 1.2 0.00023 20.8 0.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1656 PF07869.7 AEO70152.1 - 0.31 10.8 7.4 1 9.2 3.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) DUF4038 PF13204.1 AEO70152.1 - 0.41 9.9 0.0 0.71 9.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) UBA_4 PF14555.1 AEO70153.1 - 0.05 13.1 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 UBA-like domain LEDGF PF11467.3 AEO70153.1 - 0.075 12.7 0.1 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) MCLC PF05934.6 AEO70153.1 - 0.094 10.9 2.0 0.11 10.7 1.4 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) MgtE_N PF03448.12 AEO70153.1 - 0.32 11.3 3.1 1.7 8.9 0.3 2.2 1 1 1 2 2 2 0 MgtE intracellular N domain DAHP_synth_2 PF01474.11 AEO70154.1 - 1e-191 637.0 0.0 1.2e-191 636.8 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Aldose_epim PF01263.15 AEO70155.1 - 5.5e-36 124.2 0.0 6.9e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Rif1_N PF12231.3 AEO70156.1 - 4.4e-141 470.1 0.2 6.2e-141 469.6 0.1 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal DUF2605 PF10792.4 AEO70156.1 - 0.077 12.6 0.5 0.31 10.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2605) Ric8 PF10165.4 AEO70157.1 - 1.2e-129 433.0 0.0 1.3e-129 432.9 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn PUL PF08324.6 AEO70157.1 - 0.0059 15.4 0.0 1 8.0 0.0 2.7 3 0 0 3 3 3 2 PUL domain Chromo PF00385.19 AEO70158.1 - 0.00073 19.1 0.2 0.0013 18.3 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AT_hook PF02178.14 AEO70158.1 - 0.097 12.4 22.3 1 9.2 2.3 4.6 4 0 0 4 4 4 0 AT hook motif CytochromB561_N PF09786.4 AEO70158.1 - 0.69 8.2 4.8 0.87 7.9 3.3 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal PQ-loop PF04193.9 AEO70159.1 - 9.2e-24 82.7 7.4 1.2e-13 50.4 2.3 2.5 2 0 0 2 2 2 2 PQ loop repeat Sulfatase PF00884.18 AEO70160.1 - 1.8e-52 178.4 0.0 3.4e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 AEO70160.1 - 1.4e-25 88.8 2.1 2.4e-23 81.7 0.3 2.6 1 1 1 2 2 2 2 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 AEO70160.1 - 5.3e-10 39.1 0.1 9.6e-09 35.0 0.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 AEO70160.1 - 0.028 12.8 0.0 0.04 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 AEO70160.1 - 0.18 11.1 0.0 0.52 9.6 0.0 1.7 2 0 0 2 2 2 0 Metalloenzyme superfamily Med8 PF10232.4 AEO70161.1 - 8.3e-24 84.3 15.8 1.5e-22 80.1 10.9 2.0 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 FlxA PF14282.1 AEO70161.1 - 0.21 11.5 6.4 0.51 10.2 0.2 2.3 2 0 0 2 2 2 0 FlxA-like protein BTV_NS2 PF04514.7 AEO70161.1 - 0.22 10.3 6.5 0.3 9.9 4.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF972 PF06156.8 AEO70161.1 - 2 8.8 7.6 0.48 10.8 1.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Nucleoplasmin PF03066.10 AEO70161.1 - 6.3 6.3 14.1 0.21 11.0 4.8 2.0 2 0 0 2 2 2 0 Nucleoplasmin GFA PF04828.9 AEO70162.1 - 7.5e-13 48.2 5.9 5e-11 42.3 3.7 2.4 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 AEO70162.1 - 1.1 9.2 9.8 0.095 12.6 2.7 2.2 2 0 0 2 2 2 0 Cysteine-rich CWC RNase_P_p30 PF01876.11 AEO70164.1 - 1.4e-39 134.7 0.0 2.2e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 DUF3918 PF13056.1 AEO70164.1 - 0.1 11.8 1.1 0.22 10.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) DUF155 PF02582.9 AEO70166.1 - 3.7e-58 196.3 0.1 5.2e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 AT_hook PF02178.14 AEO70167.1 - 1.4 8.8 21.3 0.07 12.8 0.3 4.4 4 0 0 4 4 4 0 AT hook motif DUF2404 PF10296.4 AEO70168.1 - 0.00057 19.9 0.0 0.0031 17.6 0.0 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) VPS28 PF03997.7 AEO70169.1 - 5.2e-55 185.9 0.1 6.1e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 AEO70169.1 - 0.054 13.2 4.4 0.12 12.2 0.3 2.3 2 0 0 2 2 2 0 Gas vesicle protein G Noc2 PF03715.8 AEO70170.1 - 1.2e-122 408.4 0.0 4.4e-122 406.6 0.0 1.9 2 0 0 2 2 2 1 Noc2p family DUF726 PF05277.7 AEO70171.1 - 2.9e-112 374.9 0.4 2.9e-112 374.9 0.3 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 AEO70171.1 - 1e-05 25.5 0.8 6.1e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 AEO70171.1 - 2.8e-05 24.4 0.6 0.00029 21.1 0.0 2.5 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.2 AEO70171.1 - 0.00022 21.0 0.0 0.00073 19.3 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 AEO70171.1 - 0.021 14.2 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Lipase_3 PF01764.20 AEO70171.1 - 0.024 14.2 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) Cutinase PF01083.17 AEO70171.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Cutinase DUF900 PF05990.7 AEO70171.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Gly-zipper_OmpA PF13436.1 AEO70171.1 - 9.4 5.9 15.2 4.9 6.8 4.3 2.9 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain DUF605 PF04652.11 AEO70171.1 - 9.5 5.4 18.7 1.5 8.1 9.7 1.9 2 0 0 2 2 2 0 Vta1 like zf-RING_2 PF13639.1 AEO70172.1 - 5.3e-12 45.3 6.6 9.9e-12 44.5 4.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 AEO70172.1 - 1e-06 28.3 4.3 1.8e-06 27.5 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO70172.1 - 1.6e-06 27.9 6.9 3.3e-06 27.0 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO70172.1 - 4.5e-06 26.6 2.2 1.2e-05 25.3 1.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 AEO70172.1 - 9.4e-06 25.1 5.9 1.6e-05 24.4 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AEO70172.1 - 2.3e-05 24.1 0.5 4.9e-05 23.0 0.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 AEO70172.1 - 2.9e-05 23.6 3.3 5.1e-05 22.8 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AEO70172.1 - 0.014 15.1 1.2 0.014 15.1 0.8 2.4 2 0 0 2 2 2 0 RING-type zinc-finger DUF1049 PF06305.6 AEO70172.1 - 0.037 13.4 0.5 0.086 12.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) zf-RING_4 PF14570.1 AEO70172.1 - 0.078 12.5 3.0 0.14 11.7 2.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 AEO70172.1 - 0.13 12.1 7.3 0.24 11.2 5.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 AEO70172.1 - 0.22 11.0 3.9 0.45 10.0 2.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 AEO70172.1 - 0.27 11.3 2.9 0.47 10.5 2.0 1.4 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 AEO70172.1 - 0.33 10.9 3.4 1.5 8.7 2.4 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 AEO70172.1 - 0.63 9.7 3.2 1.2 8.8 2.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 AEO70172.1 - 1.8 8.6 3.7 3.7 7.6 2.5 1.6 1 0 0 1 1 1 0 RING-like domain Ada3 PF10198.4 AEO70173.1 - 4.2e-47 159.1 0.1 2.3e-46 156.7 0.0 2.2 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 DUF3419 PF11899.3 AEO70174.1 - 2.1e-160 533.6 0.0 2.7e-160 533.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 AEO70174.1 - 4.8e-08 32.8 0.0 1.6e-06 27.9 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO70174.1 - 8.5e-07 28.6 0.0 4.7e-05 23.0 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO70174.1 - 1.7e-06 28.4 0.0 2.7e-05 24.5 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO70174.1 - 3.7e-06 26.9 0.0 0.0036 17.3 0.0 3.9 3 2 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO70174.1 - 3.1e-05 24.5 0.0 0.00027 21.4 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO70174.1 - 0.00017 20.7 0.0 0.55 9.3 0.0 2.7 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AEO70174.1 - 0.00056 20.3 0.0 5.4 7.5 0.0 4.1 4 0 0 4 4 4 1 Methyltransferase domain PSGP PF07276.6 AEO70174.1 - 0.0019 18.2 0.6 0.0044 17.0 0.4 1.7 1 0 0 1 1 1 1 Apopolysialoglycoprotein (PSGP) Methyltransf_25 PF13649.1 AEO70174.1 - 0.033 14.5 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Fungal_trans PF04082.13 AEO70175.1 - 3.2e-11 42.6 0.1 4.5e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO70175.1 - 4.2e-07 29.7 13.7 7.2e-07 29.0 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CybS PF05328.7 AEO70176.1 - 1.7e-50 170.1 0.1 3.6e-50 169.0 0.0 1.5 2 0 0 2 2 2 1 CybS Sdh_cyt PF01127.17 AEO70176.1 - 0.011 15.5 0.4 0.061 13.1 0.3 1.9 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit tRNA-synt_1b PF00579.20 AEO70177.1 - 1.3e-80 270.6 0.0 2.1e-80 269.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NPR2 PF06218.6 AEO70178.1 - 7.4e-121 403.8 0.0 9.4e-121 403.4 0.0 1.1 1 0 0 1 1 1 1 Nitrogen permease regulator 2 Vps53_N PF04100.7 AEO70179.1 - 2.8e-101 339.0 0.3 4.8e-101 338.3 0.2 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 AEO70179.1 - 3.9e-06 25.9 3.0 7.4e-06 25.0 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 AEO70179.1 - 0.00056 18.1 2.1 0.00056 18.1 1.5 1.6 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Rbsn PF11464.3 AEO70179.1 - 0.029 13.9 0.3 0.096 12.2 0.2 1.9 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Spc7 PF08317.6 AEO70179.1 - 0.037 12.6 0.7 0.072 11.7 0.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2451 PF10474.4 AEO70179.1 - 0.046 13.4 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) FMN_red PF03358.10 AEO70180.1 - 1.1e-31 109.3 0.0 1.5e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 AEO70180.1 - 2.2e-08 33.8 0.0 2.7e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold EF-hand_1 PF00036.27 AEO70181.1 - 7.8e-11 40.4 2.3 5.9e-05 22.0 0.0 3.5 3 0 0 3 3 3 2 EF hand ZZ PF00569.12 AEO70181.1 - 2.2e-10 39.8 9.0 4.6e-10 38.8 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.1 AEO70181.1 - 6.6e-08 32.5 4.3 0.00094 19.2 0.1 3.7 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 AEO70181.1 - 2.5e-07 30.0 3.8 0.00047 19.8 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 AEO70181.1 - 3.6e-06 26.4 0.6 0.013 15.1 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair DUF1206 PF06724.6 AEO70181.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) FAM178 PF14816.1 AEO70181.1 - 0.73 8.4 1.2 1.1 7.8 0.9 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 C1_3 PF07649.7 AEO70181.1 - 1.1 9.3 9.4 2.2 8.4 6.5 1.5 1 0 0 1 1 1 0 C1-like domain SET PF00856.23 AEO70183.1 - 6.4e-07 29.8 0.0 6.9e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 SET domain NAD_binding_1 PF00175.16 AEO70184.1 - 4.2e-10 40.1 0.0 6.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AEO70184.1 - 1.1e-08 35.0 0.0 1.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AEO70184.1 - 0.031 14.1 0.1 0.14 12.0 0.0 2.0 1 1 1 2 2 2 0 Ferric reductase NAD binding domain adh_short PF00106.20 AEO70185.1 - 7.3e-28 97.5 4.9 9.5e-28 97.2 3.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO70185.1 - 8.4e-26 91.2 0.1 1.5e-25 90.3 0.0 1.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO70185.1 - 5.6e-15 55.4 2.8 8.3e-15 54.9 1.9 1.2 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.13 AEO70187.1 - 3.2e-08 32.7 0.2 6.8e-08 31.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO70187.1 - 3.1e-06 26.9 10.2 3.1e-06 26.9 7.1 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF718 PF05336.8 AEO70188.1 - 0.23 11.3 3.1 0.42 10.4 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF718) Glyco_hydro_47 PF01532.15 AEO70189.1 - 1.4e-135 452.5 0.0 1.6e-135 452.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pribosyltran PF00156.22 AEO70190.1 - 2.3e-16 59.6 0.0 3.8e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AEO70190.1 - 0.011 14.9 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Ribosomal_60s PF00428.14 AEO70191.1 - 0.071 13.5 5.7 0.11 12.8 3.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein AflR PF08493.5 AEO70192.1 - 6.9 5.6 6.6 7.4 5.5 4.6 1.0 1 0 0 1 1 1 0 Aflatoxin regulatory protein IBN_N PF03810.14 AEO70193.1 - 3.1e-15 55.8 0.3 2.9e-14 52.7 0.4 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 AEO70193.1 - 3.1e-06 27.1 1.2 0.00045 20.1 0.0 4.1 3 1 0 4 4 4 1 Exportin 1-like protein 3HCDH_N PF02737.13 AEO70194.1 - 1.2e-33 116.2 0.0 1.6e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 AEO70194.1 - 8e-14 51.8 0.0 1.4e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 AEO70194.1 - 1.1e-05 25.2 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 AEO70194.1 - 0.0013 18.5 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 AEO70194.1 - 0.022 13.8 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 AEO70194.1 - 0.035 13.4 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 AEO70194.1 - 0.064 13.6 0.0 0.24 11.8 0.0 1.9 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 AEO70194.1 - 0.16 11.3 0.0 0.54 9.6 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pex2_Pex12 PF04757.9 AEO70195.1 - 9.5e-40 136.4 0.4 1.6e-39 135.6 0.3 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 AEO70195.1 - 0.00067 19.4 4.1 0.0013 18.5 2.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 AEO70195.1 - 0.014 15.4 2.3 0.014 15.4 1.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ferric_reduct PF01794.14 AEO70195.1 - 0.056 13.5 1.8 0.11 12.5 1.3 1.4 1 0 0 1 1 1 0 Ferric reductase like transmembrane component zf-RING_UBOX PF13445.1 AEO70195.1 - 0.06 13.0 0.3 0.14 11.8 0.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger CDK2AP PF09806.4 AEO70195.1 - 0.13 12.4 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein tRNA-synt_1 PF00133.17 AEO70196.1 - 4.8e-31 107.4 0.0 2.3e-30 105.1 0.0 2.0 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AEO70196.1 - 3.5e-11 43.0 0.0 6.4e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AEO70196.1 - 5.6e-11 41.7 0.1 8.1e-10 37.9 0.0 2.6 4 0 0 4 4 4 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 AEO70196.1 - 6.5e-06 25.4 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain YchF-GTPase_C PF06071.8 AEO70196.1 - 0.021 14.5 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF933) FAD_binding_8 PF08022.7 AEO70197.1 - 3.9e-24 84.5 0.0 7.5e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 AEO70197.1 - 5.8e-23 81.5 0.0 9.4e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 AEO70197.1 - 1.1e-17 64.2 9.7 1.1e-17 64.2 6.7 1.9 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 AEO70197.1 - 2.9e-05 24.1 0.0 9.5e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 AEO70197.1 - 0.12 12.8 0.0 2.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Myosin_head PF00063.16 AEO70198.1 - 6.8e-233 774.6 1.4 1e-232 774.0 0.9 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 AEO70198.1 - 2.1e-39 134.9 0.0 5.2e-39 133.6 0.0 1.7 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 AEO70198.1 - 8.3e-13 47.5 0.2 1.6e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AEO70198.1 - 1.2e-10 40.8 0.1 2.7e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AEO70198.1 - 1.2e-08 34.3 0.0 4.8e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain IQ PF00612.22 AEO70198.1 - 0.0011 18.3 10.5 0.04 13.5 1.7 2.8 1 1 1 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 AEO70198.1 - 0.0051 16.9 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Hpr_kinase_C PF07475.7 AEO70198.1 - 0.017 14.4 0.2 2.9 7.1 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.7 AEO70198.1 - 0.019 14.0 0.0 0.046 12.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF552 PF04472.7 AEO70198.1 - 0.022 14.6 0.0 0.064 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF552) AAA_17 PF13207.1 AEO70198.1 - 0.052 14.3 0.0 0.19 12.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AEO70198.1 - 0.084 12.5 0.1 0.3 10.7 0.0 1.9 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.1 AEO70198.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-DHHC PF01529.15 AEO70199.1 - 2.5e-32 111.6 0.0 3.6e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 AEO70199.1 - 0.011 15.5 1.7 0.034 13.9 1.2 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily DZR PF12773.2 AEO70199.1 - 0.092 12.5 7.5 0.17 11.7 5.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon FYVE PF01363.16 AEO70199.1 - 2.9 7.8 14.5 8.7 6.3 10.0 1.7 1 1 0 1 1 1 0 FYVE zinc finger Glyco_transf_90 PF05686.7 AEO70200.1 - 6.9e-09 34.8 0.5 0.032 12.9 0.2 4.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 Lactamase_B PF00753.22 AEO70201.1 - 5e-08 32.8 0.0 7.3e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_hydro_18 PF00704.23 AEO70202.1 - 6.3e-61 206.7 0.0 7.1e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.18 AEO70203.1 - 8.1e-17 60.3 0.1 1.2e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 AEO70203.1 - 1.2e-09 37.7 0.0 4.4e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD_2 PF13881.1 AEO70203.1 - 0.00048 19.9 0.0 0.0022 17.8 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AEO70203.1 - 0.0025 17.9 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 AEO70203.1 - 0.0041 16.7 0.2 0.0061 16.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Mpv17_PMP22 PF04117.7 AEO70204.1 - 3.8e-26 90.5 1.9 6.7e-26 89.7 1.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family UDPGP PF01704.13 AEO70205.1 - 6.8e-52 176.3 0.0 9.4e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 AEO70205.1 - 0.0088 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fer4_20 PF14691.1 AEO70205.1 - 0.056 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster UDG PF03167.14 AEO70206.1 - 3.4e-24 85.0 0.0 5.3e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily zf-B_box PF00643.19 AEO70208.1 - 0.073 12.9 1.1 0.1 12.4 0.8 1.2 1 0 0 1 1 1 0 B-box zinc finger zf-C3HC4_2 PF13923.1 AEO70208.1 - 0.65 10.0 5.0 1.1 9.3 3.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LMBR1 PF04791.11 AEO70209.1 - 6.2e-17 61.3 0.1 6.2e-17 61.3 0.1 2.5 2 1 0 2 2 2 1 LMBR1-like membrane protein CPSF_A PF03178.10 AEO70210.1 - 4.5e-85 285.5 0.0 3.3e-84 282.7 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region PBP1_TM PF14812.1 AEO70210.1 - 0.68 10.2 3.7 2.2 8.6 2.6 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pal1 PF08316.6 AEO70211.1 - 5.8e-10 39.7 0.0 8.6e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Pal1 cell morphology protein HVSL PF09749.4 AEO70212.1 - 8.2e-67 224.7 0.0 9.2e-67 224.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein ERO1 PF04137.10 AEO70213.1 - 7.8e-138 459.3 0.0 4.7e-137 456.7 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Cytochrom_C_2 PF01322.15 AEO70213.1 - 2.6 8.6 6.4 0.55 10.7 1.5 2.0 2 1 0 2 2 2 0 Cytochrome C' CKS PF01111.14 AEO70214.1 - 9.4e-35 118.2 0.6 1.5e-34 117.6 0.4 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Bromodomain PF00439.20 AEO70215.1 - 3e-36 123.2 0.1 2.3e-19 69.1 0.3 2.3 2 0 0 2 2 2 2 Bromodomain zf-UBP PF02148.14 AEO70215.1 - 0.056 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein CLAMP PF14769.1 AEO70215.1 - 0.13 12.4 0.2 0.32 11.1 0.2 1.6 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Nop14 PF04147.7 AEO70215.1 - 4.7 4.9 10.4 6.2 4.6 7.2 1.2 1 0 0 1 1 1 0 Nop14-like family G-patch PF01585.18 AEO70217.1 - 0.17 11.7 1.2 0.92 9.3 0.8 2.2 1 1 0 1 1 1 0 G-patch domain CAF-1_p150 PF11600.3 AEO70217.1 - 0.43 9.9 29.1 0.59 9.4 20.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Dsh_C PF12316.3 AEO70217.1 - 2.3 8.3 15.6 3.3 7.7 10.8 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Thg1C PF14413.1 AEO70218.1 - 2e-52 175.9 0.1 2.7e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 AEO70218.1 - 7.8e-49 164.7 0.0 1.1e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase WD40 PF00400.27 AEO70219.1 - 3.4e-14 52.0 4.3 4.5e-06 26.3 0.3 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.6 AEO70219.1 - 1.7e-06 27.8 0.0 0.014 15.0 0.0 3.4 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 AEO70219.1 - 0.045 13.1 0.2 0.32 10.4 0.1 2.4 1 1 1 2 2 2 0 PQQ-like domain RNA_pol_Rpb1_1 PF04997.7 AEO70220.1 - 4.5e-111 371.3 0.0 8.9e-111 370.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 AEO70220.1 - 1.9e-100 335.7 0.1 4e-100 334.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 AEO70220.1 - 5.6e-70 234.5 0.0 1.2e-69 233.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 AEO70220.1 - 4.6e-60 202.5 3.3 1.1e-59 201.3 2.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 AEO70220.1 - 8.4e-46 155.5 0.0 2.3e-45 154.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 AEO70220.1 - 9.1e-45 151.6 8.3 1.4e-44 151.0 5.2 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 AEO70220.1 - 4.1e-38 129.4 0.1 9.7e-38 128.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Upf2 PF04050.9 AEO70220.1 - 0.013 15.2 1.1 0.034 13.9 0.7 1.6 1 0 0 1 1 1 0 Up-frameshift suppressor 2 zf-C4pol PF14260.1 AEO70220.1 - 0.19 11.7 0.1 0.48 10.4 0.0 1.6 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta RNA_pol_Rpb1_R PF05001.8 AEO70220.1 - 0.62 10.3 194.8 0.042 13.9 8.0 13.7 7 3 7 15 15 15 0 RNA polymerase Rpb1 C-terminal repeat HemY_N PF07219.8 AEO70222.1 - 0.033 13.7 0.1 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 HemY protein N-terminus F-box PF00646.28 AEO70223.1 - 0.34 10.6 0.1 0.34 10.6 0.1 2.0 2 0 0 2 2 2 0 F-box domain HSP70 PF00012.15 AEO70224.1 - 2.9e-236 785.0 8.2 3.3e-236 784.9 5.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AEO70224.1 - 2.9e-16 58.9 0.5 2.9e-15 55.6 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 AEO70224.1 - 0.0016 18.0 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 AEO70224.1 - 0.017 13.9 0.3 0.13 11.0 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.1 AEO70224.1 - 0.045 13.5 2.0 13 5.6 0.0 4.0 3 1 0 3 3 3 0 Cell division protein FtsA IF4E PF01652.13 AEO70225.1 - 1.5e-60 203.5 0.1 1.8e-60 203.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.23 AEO70226.1 - 2.5e-71 240.2 0.0 3.4e-71 239.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO70226.1 - 1.4e-09 38.7 0.2 3e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BolA PF01722.13 AEO70227.1 - 3.4e-29 100.5 0.5 4e-29 100.3 0.3 1.1 1 0 0 1 1 1 1 BolA-like protein PIP5K PF01504.13 AEO70229.1 - 3.2e-58 196.8 0.2 6.7e-58 195.7 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 AEO70229.1 - 9.1e-26 90.5 0.0 1.7e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 AEO70229.1 - 1.5e-13 50.4 9.5 1.5e-13 50.4 6.6 2.2 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.11 AEO70229.1 - 2.6 7.9 11.2 0.11 12.4 3.3 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger Ribosomal_60s PF00428.14 AEO70231.1 - 0.14 12.5 16.1 0.16 12.3 1.8 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein Cyclin_N PF00134.18 AEO70232.1 - 2.8e-38 130.3 0.1 2.8e-38 130.3 0.1 2.7 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AEO70232.1 - 1.3e-13 50.9 4.0 6.5e-13 48.6 0.1 2.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain PAT1 PF09770.4 AEO70232.1 - 0.0017 16.7 18.2 0.0022 16.3 12.6 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 AEO70232.1 - 0.21 10.9 13.1 0.29 10.4 9.1 1.1 1 0 0 1 1 1 0 Vta1 like Transglut_core PF01841.14 AEO70236.1 - 1.7e-15 57.1 2.7 3.9e-15 56.0 1.9 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.10 AEO70236.1 - 3.8e-15 55.5 4.6 6.5e-15 54.7 3.2 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain WD40 PF00400.27 AEO70237.1 - 1.6e-06 27.7 12.2 0.0025 17.6 0.0 7.6 8 0 0 8 8 8 2 WD domain, G-beta repeat NAPRTase PF04095.11 AEO70238.1 - 2.1e-51 174.5 0.6 2.7e-50 170.9 0.4 2.0 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Methyltransf_23 PF13489.1 AEO70239.1 - 4e-14 52.6 0.0 6.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO70239.1 - 3.7e-11 42.8 0.0 2.3e-10 40.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO70239.1 - 9.7e-09 35.6 0.0 2.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO70239.1 - 1.5e-08 35.2 0.1 2.3e-07 31.4 0.0 2.4 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO70239.1 - 2e-06 28.2 0.0 1.1e-05 25.8 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO70239.1 - 3.2e-05 24.2 0.0 0.00012 22.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 AEO70239.1 - 0.00055 19.3 0.0 0.00088 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 AEO70239.1 - 0.0037 16.3 0.0 0.014 14.4 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 AEO70239.1 - 0.0048 16.9 0.0 0.019 15.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 AEO70239.1 - 0.0053 16.2 0.0 0.0086 15.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 AEO70239.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase GidB PF02527.10 AEO70239.1 - 0.035 13.2 0.0 7.5 5.6 0.0 2.1 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G ATP-synt_G PF04718.10 AEO70240.1 - 6.7e-28 97.3 0.6 1.5e-26 92.9 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit MTBP_C PF14920.1 AEO70240.1 - 4.9 6.5 8.0 8.4 5.8 5.3 1.5 1 1 1 2 2 2 0 MDM2-binding ADH_N PF08240.7 AEO70241.1 - 3.8e-27 94.1 2.2 7.7e-27 93.2 1.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO70241.1 - 1.5e-15 56.8 0.0 2.4e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 AEO70241.1 - 0.009 15.7 0.1 0.46 10.2 0.0 2.6 2 0 0 2 2 2 1 S1-like ADH_zinc_N_2 PF13602.1 AEO70241.1 - 0.037 14.9 0.0 0.067 14.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Bap31 PF05529.7 AEO70242.1 - 1.7e-57 194.0 1.5 1.9e-57 193.8 1.0 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF465 PF04325.8 AEO70242.1 - 2.4 7.9 8.6 0.59 9.8 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF465) DivIC PF04977.10 AEO70242.1 - 2.5 7.6 10.6 0.29 10.6 1.0 3.2 3 1 1 4 4 4 0 Septum formation initiator DUF1479 PF07350.7 AEO70243.1 - 2.4e-146 487.4 0.0 3e-146 487.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) HHH PF00633.18 AEO70243.1 - 0.026 14.2 0.1 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif PhyH PF05721.8 AEO70243.1 - 0.057 13.4 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) zf-met2 PF12907.2 AEO70244.1 - 3.6e-14 52.4 2.1 5e-14 51.9 1.5 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 AEO70244.1 - 0.0028 18.3 8.7 0.0053 17.4 6.0 1.5 1 0 0 1 1 1 1 4F5 protein family DIOX_N PF14226.1 AEO70245.1 - 4.2e-32 111.1 0.0 4.1e-30 104.6 0.0 2.3 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 AEO70245.1 - 3.5e-14 52.9 0.0 6.4e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 AEO70246.1 - 2.4e-10 39.8 4.7 0.00012 21.8 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat RNA_pol_N PF01194.12 AEO70247.1 - 8.2e-29 99.4 1.3 1.1e-28 98.9 0.9 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 AEO70247.1 - 0.028 14.5 0.6 0.041 13.9 0.4 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DUF416 PF04222.7 AEO70248.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF416) Methyltransf_16 PF10294.4 AEO70250.1 - 2.8e-21 75.7 0.0 3.6e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 AEO70250.1 - 0.0017 18.9 0.0 0.003 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AEO70250.1 - 0.023 13.8 0.0 0.031 13.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 AEO70250.1 - 0.037 13.7 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 AEO70250.1 - 0.088 12.1 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Utp21 PF04192.7 AEO70251.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Dynein_light PF01221.13 AEO70253.1 - 3.7e-41 139.0 0.8 4.3e-41 138.8 0.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RRM_1 PF00076.17 AEO70254.1 - 4e-67 221.7 1.4 1.6e-16 59.6 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO70254.1 - 1.2e-61 204.5 0.9 2.7e-14 52.8 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO70254.1 - 2.5e-27 94.4 0.1 1.3e-06 28.1 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TEA PF01285.13 AEO70254.1 - 1.9e-08 33.9 0.0 1.9e-08 33.9 0.0 2.5 3 0 0 3 3 3 1 TEA/ATTS domain family Limkain-b1 PF11608.3 AEO70254.1 - 4.8e-05 23.0 1.9 0.14 11.8 0.0 4.2 4 1 0 4 4 4 2 Limkain b1 Nup35_RRM_2 PF14605.1 AEO70254.1 - 9e-05 22.1 0.0 5.3 6.8 0.0 4.3 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 AEO70254.1 - 0.054 13.3 0.0 3.7 7.4 0.0 3.4 3 0 0 3 3 3 0 RNA binding motif Nup35_RRM PF05172.8 AEO70254.1 - 0.31 10.8 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Pro_isomerase PF00160.16 AEO70256.1 - 1e-48 165.4 0.2 1.2e-48 165.2 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 AEO70256.1 - 0.086 12.6 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Dus PF01207.12 AEO70257.1 - 5.3e-40 137.1 0.0 4e-29 101.4 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 AEO70257.1 - 0.059 13.0 5.3 1.9 8.2 0.3 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Kelch_4 PF13418.1 AEO70258.1 - 1.3e-43 146.5 16.6 1.7e-09 37.2 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 AEO70258.1 - 6.2e-41 137.7 13.1 4.5e-07 29.6 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 AEO70258.1 - 1e-40 136.9 24.0 5.2e-09 36.0 0.0 7.2 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.20 AEO70258.1 - 7.7e-39 131.0 14.3 3.2e-08 32.9 1.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 AEO70258.1 - 1.2e-35 120.1 14.2 7.1e-07 29.1 0.0 6.7 6 1 1 7 7 7 6 Kelch motif Kelch_2 PF07646.10 AEO70258.1 - 2e-32 109.7 13.9 9.8e-09 34.6 0.3 6.5 6 0 0 6 6 6 6 Kelch motif HIG_1_N PF04588.8 AEO70259.1 - 1.6e-07 30.9 2.3 1.6e-07 30.9 1.6 2.5 3 0 0 3 3 3 1 Hypoxia induced protein conserved region DUF4079 PF13301.1 AEO70259.1 - 0.031 14.2 1.1 0.044 13.7 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF998 PF06197.8 AEO70259.1 - 0.059 12.6 4.4 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Romo1 PF10247.4 AEO70259.1 - 0.072 13.3 2.8 0.14 12.3 2.0 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 CbtA PF09490.5 AEO70259.1 - 0.098 11.9 3.8 0.049 12.9 0.9 1.8 1 1 1 2 2 2 0 Probable cobalt transporter subunit (CbtA) zf-H2C2_2 PF13465.1 AEO70260.1 - 4.6e-05 23.5 5.7 0.0054 16.9 0.3 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO70260.1 - 0.0054 16.9 15.1 0.049 13.9 0.3 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO70260.1 - 0.021 14.9 0.2 0.021 14.9 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AEO70260.1 - 0.023 14.6 0.8 0.023 14.6 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO70260.1 - 1.6 9.2 20.4 0.12 12.7 1.1 3.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type Kelch_4 PF13418.1 AEO70261.1 - 1.4e-27 95.1 7.0 1.3e-08 34.5 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 AEO70261.1 - 1.3e-23 82.4 5.7 6e-07 29.2 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 AEO70261.1 - 2.5e-22 78.0 4.3 0.00018 21.4 0.0 5.4 4 1 2 6 6 6 4 Kelch motif Kelch_1 PF01344.20 AEO70261.1 - 1.5e-21 75.6 0.6 4.9e-05 22.7 0.1 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.1 AEO70261.1 - 4.6e-21 74.4 8.1 3.2e-07 30.3 0.1 5.6 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_2 PF07646.10 AEO70261.1 - 3.7e-18 64.5 3.9 0.0016 18.1 0.0 5.0 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 AEO70261.1 - 3.4e-09 36.6 0.0 5.9e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Rax2 PF12768.2 AEO70261.1 - 0.17 11.0 0.0 0.61 9.2 0.0 1.8 1 1 1 2 2 2 0 Cortical protein marker for cell polarity WD40 PF00400.27 AEO70262.1 - 6e-21 73.4 20.7 1.8e-06 27.5 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 AEO70262.1 - 1.7e-06 27.8 0.4 5.7e-05 22.9 0.1 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 AEO70262.1 - 0.058 12.8 0.0 0.36 10.3 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Sulfate_transp PF00916.15 AEO70263.1 - 1e-34 119.8 0.9 2.9e-34 118.3 0.6 1.8 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 AEO70263.1 - 8.9e-14 51.0 0.0 1.8e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 AEO70263.1 - 2.5e-10 39.7 0.0 5.2e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain DUF2964 PF11177.3 AEO70263.1 - 0.051 13.5 3.0 1.3 9.0 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) TFIIA PF03153.8 AEO70264.1 - 1.3e-88 298.5 4.1 2.1e-88 297.7 2.9 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit YL1 PF05764.8 AEO70264.1 - 0.086 12.4 3.2 0.18 11.3 2.2 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 AEO70264.1 - 0.37 8.6 6.4 0.49 8.2 4.5 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 AEO70264.1 - 0.41 10.3 5.8 0.78 9.4 4.0 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.5 AEO70264.1 - 7.3 6.8 12.0 13 6.0 8.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peroxin-13_N PF04088.8 AEO70265.1 - 4.6e-57 192.4 0.0 7.3e-57 191.7 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 AEO70265.1 - 8.8e-08 31.5 0.0 1.6e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AEO70265.1 - 1.2e-05 24.5 0.1 2.8e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AEO70265.1 - 1.3e-05 24.7 0.0 2.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Med3 PF11593.3 AEO70265.1 - 3.2 6.8 20.9 0.19 10.9 9.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF4349 PF14257.1 AEO70265.1 - 6.3 5.9 7.5 68 2.5 4.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) HSP70 PF00012.15 AEO70266.1 - 7.7e-84 281.7 0.0 9.6e-52 175.7 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein p450 PF00067.17 AEO70267.1 - 4.7e-69 233.0 0.0 6.1e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 YjgP_YjgQ PF03739.9 AEO70267.1 - 0.29 9.8 1.3 0.55 8.9 0.9 1.4 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Glyco_transf_11 PF01531.11 AEO70268.1 - 0.063 12.2 0.0 0.14 11.1 0.0 1.4 2 0 0 2 2 2 0 Glycosyl transferase family 11 Kinesin PF00225.18 AEO70269.1 - 7.9e-99 330.5 0.0 1.2e-98 329.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Stk19 PF10494.4 AEO70270.1 - 1.8e-34 119.2 0.0 1.9e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Sld5 PF05916.6 AEO70271.1 - 1.4e-12 47.8 0.0 2e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein AAA_2 PF07724.9 AEO70272.1 - 2.5e-44 151.2 0.0 4e-43 147.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 AEO70272.1 - 3.4e-24 84.5 0.2 1.1e-23 82.9 0.1 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 AEO70272.1 - 2.6e-19 69.7 0.1 3.5e-10 40.1 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AEO70272.1 - 2.9e-11 43.2 0.0 1.7e-08 34.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AEO70272.1 - 2e-08 34.4 14.0 0.0064 16.4 0.1 5.2 4 2 2 6 6 5 3 AAA ATPase domain AAA_22 PF13401.1 AEO70272.1 - 2.2e-08 34.2 0.6 0.0097 16.0 0.0 3.6 2 2 1 3 3 2 2 AAA domain Sigma54_activat PF00158.21 AEO70272.1 - 1.3e-06 27.9 0.4 0.00046 19.6 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 AEO70272.1 - 3e-06 27.1 0.0 0.097 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 AEO70272.1 - 9e-06 25.5 7.9 0.016 14.8 0.2 4.6 3 2 0 3 3 3 1 Archaeal ATPase NACHT PF05729.7 AEO70272.1 - 2.6e-05 23.9 0.2 0.19 11.3 0.1 2.9 2 1 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 AEO70272.1 - 0.00021 21.5 3.2 0.15 12.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 AEO70272.1 - 0.00026 21.8 6.2 0.027 15.2 0.3 4.3 4 1 0 4 4 3 1 AAA domain IstB_IS21 PF01695.12 AEO70272.1 - 0.00028 20.3 0.0 0.26 10.7 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF258 PF03193.11 AEO70272.1 - 0.0013 17.9 0.1 1 8.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 AEO70272.1 - 0.0014 18.3 0.1 0.27 10.9 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 AEO70272.1 - 0.0034 17.5 0.0 0.99 9.6 0.0 2.9 2 1 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 AEO70272.1 - 0.0043 17.0 0.7 6.5 6.6 0.0 3.8 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.22 AEO70272.1 - 0.0046 17.2 1.3 0.27 11.5 0.0 3.1 3 0 0 3 3 3 1 ABC transporter AAA_33 PF13671.1 AEO70272.1 - 0.0047 16.8 0.0 5.6 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 AEO70272.1 - 0.0054 16.4 0.0 0.84 9.4 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain IncA PF04156.9 AEO70272.1 - 0.0081 15.7 8.4 0.0098 15.4 4.9 1.8 2 0 0 2 2 1 1 IncA protein SRP54 PF00448.17 AEO70272.1 - 0.0088 15.5 0.0 0.47 9.8 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ERM PF00769.14 AEO70272.1 - 0.014 14.8 8.9 0.026 14.0 6.1 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AAA_25 PF13481.1 AEO70272.1 - 0.015 14.6 0.4 4.1 6.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain ResIII PF04851.10 AEO70272.1 - 0.017 14.9 0.8 12 5.6 0.0 3.8 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.4 AEO70272.1 - 0.018 13.6 0.0 1.3 7.5 0.0 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Seryl_tRNA_N PF02403.17 AEO70272.1 - 0.028 14.4 14.4 0.031 14.3 8.4 2.4 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain AAA_10 PF12846.2 AEO70272.1 - 0.036 13.4 0.1 0.71 9.2 0.0 3.0 2 2 1 3 3 2 0 AAA-like domain Mg_chelatase PF01078.16 AEO70272.1 - 0.044 12.9 0.2 2.5 7.2 0.0 2.9 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI OEP PF02321.13 AEO70272.1 - 0.048 13.2 10.1 0.11 12.0 7.0 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein PduV-EutP PF10662.4 AEO70272.1 - 0.065 12.7 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation APG6 PF04111.7 AEO70272.1 - 0.067 12.2 5.8 0.11 11.5 4.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Miro PF08477.8 AEO70272.1 - 0.074 13.5 0.1 5.1 7.6 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 AEO70272.1 - 0.081 12.5 0.0 2 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain V_ATPase_I PF01496.14 AEO70272.1 - 0.15 9.9 3.1 0.21 9.3 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATP_bind_1 PF03029.12 AEO70272.1 - 0.16 11.5 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GrpE PF01025.14 AEO70272.1 - 0.17 11.4 7.8 0.42 10.1 5.4 1.6 1 0 0 1 1 1 0 GrpE ADIP PF11559.3 AEO70272.1 - 0.66 9.8 10.3 1.3 8.8 7.2 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Mnd1 PF03962.10 AEO70272.1 - 1.1 8.8 11.2 2.1 7.9 7.7 1.4 1 0 0 1 1 1 0 Mnd1 family Atg14 PF10186.4 AEO70272.1 - 2.4 7.0 9.1 4.1 6.2 6.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Arf PF00025.16 AEO70273.1 - 2.2e-78 261.4 0.2 2.6e-78 261.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AEO70273.1 - 1.9e-13 50.0 0.0 2.5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AEO70273.1 - 6.4e-13 48.4 0.0 7e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 AEO70273.1 - 1.5e-12 46.9 1.1 5e-09 35.3 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 AEO70273.1 - 3.3e-11 42.7 0.0 3.9e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AEO70273.1 - 1.4e-08 35.2 0.0 2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AEO70273.1 - 9.7e-06 25.5 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 AEO70273.1 - 0.0024 16.9 0.1 0.0056 15.7 0.0 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 AEO70273.1 - 0.017 14.5 0.1 0.12 11.7 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 AEO70273.1 - 0.042 13.7 0.1 0.084 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain EMP24_GP25L PF01105.19 AEO70274.1 - 9.4e-45 152.5 0.0 1.1e-44 152.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dioxygenase_C PF00775.16 AEO70274.1 - 0.0097 15.1 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase SpoU_methylase PF00588.14 AEO70274.1 - 0.13 12.1 0.0 2.2 8.1 0.0 2.1 1 1 1 2 2 2 0 SpoU rRNA Methylase family DUF3405 PF11885.3 AEO70275.1 - 5.7e-214 710.9 0.1 5.7e-214 710.9 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) FAD_binding_2 PF00890.19 AEO70276.1 - 7.4e-125 417.0 3.6 9.1e-125 416.7 2.5 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 AEO70276.1 - 3.1e-48 162.8 0.5 4.6e-48 162.3 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 AEO70276.1 - 5.1e-07 29.7 0.0 0.0023 17.8 0.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO70276.1 - 1.1e-05 24.7 0.3 0.0081 15.2 0.0 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 AEO70276.1 - 2.4e-05 23.3 1.2 0.014 14.2 1.5 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 AEO70276.1 - 0.0011 17.9 0.2 0.0035 16.2 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AEO70276.1 - 0.0039 16.2 0.1 0.0076 15.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 AEO70276.1 - 0.035 14.1 1.4 1.1 9.2 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO70276.1 - 0.086 11.2 1.2 0.24 9.8 0.4 2.0 2 0 0 2 2 2 0 HI0933-like protein DUF3818 PF12825.2 AEO70277.1 - 1.3e-137 458.1 4.3 1.7e-137 457.6 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 AEO70277.1 - 9.7e-43 145.0 2.9 1.3e-42 144.6 1.1 1.9 2 0 0 2 2 2 1 PX-associated PX PF00787.19 AEO70277.1 - 1.6e-13 50.4 0.3 4.4e-12 45.8 0.0 3.3 3 1 0 3 3 3 1 PX domain HOOK PF05622.7 AEO70279.1 - 0.0014 16.5 0.1 0.0019 16.1 0.0 1.0 1 0 0 1 1 1 1 HOOK protein Spc7 PF08317.6 AEO70279.1 - 0.0046 15.6 2.0 0.0066 15.1 1.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF2077 PF09850.4 AEO70279.1 - 0.0061 15.9 0.2 0.016 14.6 0.1 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2077) CSF-1 PF05337.6 AEO70279.1 - 0.014 14.7 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) COG2 PF06148.6 AEO70279.1 - 0.014 15.2 1.7 1.1 9.1 0.2 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Reo_sigmaC PF04582.7 AEO70279.1 - 0.017 14.3 0.7 0.025 13.7 0.5 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein BBP1_C PF15272.1 AEO70279.1 - 0.024 14.2 0.9 0.041 13.4 0.7 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Med9 PF07544.8 AEO70279.1 - 0.024 14.3 3.5 0.21 11.3 1.3 2.7 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 AIP3 PF03915.8 AEO70279.1 - 0.027 13.3 0.6 0.042 12.7 0.4 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 Prominin PF05478.6 AEO70279.1 - 0.03 11.8 0.5 0.16 9.4 0.0 1.9 1 1 0 1 1 1 0 Prominin LUC7 PF03194.10 AEO70279.1 - 0.035 13.6 0.2 0.048 13.1 0.1 1.2 1 0 0 1 1 1 0 LUC7 N_terminus Snapin_Pallidin PF14712.1 AEO70279.1 - 0.036 14.3 0.9 0.17 12.1 0.2 2.2 1 1 1 2 2 2 0 Snapin/Pallidin FUSC PF04632.7 AEO70279.1 - 0.042 12.2 3.2 0.063 11.7 2.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF904 PF06005.7 AEO70279.1 - 0.061 13.6 0.7 1.8 8.9 0.5 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) HalX PF08663.5 AEO70279.1 - 0.065 13.2 10.1 3.6 7.6 1.9 4.0 1 1 3 4 4 4 0 HalX domain Matrilin_ccoil PF10393.4 AEO70279.1 - 0.075 12.4 0.0 0.3 10.4 0.0 2.0 2 0 0 2 2 1 0 Trimeric coiled-coil oligomerisation domain of matrilin SlyX PF04102.7 AEO70279.1 - 0.12 12.7 2.3 4.7 7.6 0.2 2.5 2 0 0 2 2 2 0 SlyX Seryl_tRNA_N PF02403.17 AEO70279.1 - 0.14 12.1 3.8 2.2 8.3 1.5 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.4 AEO70279.1 - 0.16 11.8 4.4 0.22 11.3 0.9 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.5 AEO70279.1 - 0.19 11.8 0.3 1.8 8.6 0.2 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.8 AEO70279.1 - 0.26 12.0 0.9 1.3 9.7 0.2 2.2 1 1 1 2 2 2 0 Occludin homology domain TBPIP PF07106.8 AEO70279.1 - 0.3 10.6 1.1 1 8.8 0.7 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 AEO70279.1 - 0.31 10.5 2.0 1.1 8.7 0.2 2.4 1 1 1 2 2 2 0 Septum formation initiator TMF_TATA_bd PF12325.3 AEO70279.1 - 0.34 10.6 2.1 0.98 9.1 0.1 2.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF2721 PF11026.3 AEO70279.1 - 0.38 10.3 3.1 3.4 7.3 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) EMP24_GP25L PF01105.19 AEO70279.1 - 0.41 10.3 2.2 1 9.0 1.5 1.7 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD IncA PF04156.9 AEO70279.1 - 0.41 10.2 11.8 0.76 9.3 6.5 2.3 1 1 0 1 1 1 0 IncA protein T2SF PF00482.18 AEO70279.1 - 0.42 10.5 2.1 16 5.3 0.0 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Syntaxin-6_N PF09177.6 AEO70279.1 - 0.78 10.1 6.5 0.55 10.6 0.2 2.7 2 1 1 3 3 2 0 Syntaxin 6, N-terminal Atg14 PF10186.4 AEO70279.1 - 1.3 7.9 5.0 3.8 6.3 3.4 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Cgr1 PF03879.9 AEO70280.1 - 1.3e-16 60.7 2.9 2e-16 60.1 2.0 1.3 1 0 0 1 1 1 1 Cgr1 family UQ_con PF00179.21 AEO70282.1 - 3.5e-29 101.0 0.0 4.1e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO70282.1 - 8.6e-05 22.3 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AEO70282.1 - 0.08 12.8 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain Anp1 PF03452.9 AEO70283.1 - 2.6e-108 361.2 0.0 3.3e-108 360.9 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 AEO70283.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Proteasom_Rpn13 PF04683.8 AEO70284.1 - 5.7e-27 93.6 0.0 9e-27 92.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RRM_6 PF14259.1 AEO70285.1 - 5.3e-12 45.5 0.1 5.1e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO70285.1 - 1.7e-11 43.6 0.1 3.7e-05 23.2 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO70285.1 - 2.2e-06 27.3 0.0 9e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AICARFT_IMPCHas PF01808.13 AEO70286.1 - 4.2e-110 367.7 0.0 5.5e-110 367.3 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 AEO70286.1 - 1.9e-23 82.1 0.0 3.7e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain DUF1237 PF06824.6 AEO70287.1 - 2.3e-179 596.4 0.0 2.8e-179 596.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Mucin PF01456.12 AEO70287.1 - 0.0039 16.9 9.6 0.31 10.8 1.1 2.4 2 0 0 2 2 2 2 Mucin-like glycoprotein Abhydro_lipase PF04083.11 AEO70288.1 - 1e-19 69.6 0.0 2.8e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 AEO70288.1 - 4.9e-05 23.3 4.9 4.9e-05 23.3 3.4 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO70288.1 - 0.0014 18.3 0.0 0.003 17.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family AAA PF00004.24 AEO70289.1 - 5.9e-50 168.8 0.0 1.6e-43 148.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 AEO70289.1 - 7.5e-05 22.2 0.0 0.00057 19.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO70289.1 - 0.00012 22.8 0.0 0.00045 21.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AEO70289.1 - 0.00023 20.3 0.0 0.00051 19.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AEO70289.1 - 0.00067 19.8 0.0 0.0048 17.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 AEO70289.1 - 0.00073 18.4 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.12 AEO70289.1 - 0.0012 18.3 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 AEO70289.1 - 0.0026 17.9 0.0 0.033 14.3 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 AEO70289.1 - 0.0027 17.6 3.6 0.023 14.7 0.0 3.5 3 1 1 4 4 4 1 AAA ATPase domain AAA_19 PF13245.1 AEO70289.1 - 0.0028 17.3 0.0 0.018 14.8 0.0 2.4 1 0 0 1 1 1 1 Part of AAA domain AAA_2 PF07724.9 AEO70289.1 - 0.0034 17.3 0.0 0.0077 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 AEO70289.1 - 0.011 14.5 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_5 PF07728.9 AEO70289.1 - 0.013 15.2 0.1 0.067 12.9 0.0 2.4 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 AEO70289.1 - 0.02 14.0 0.1 0.048 12.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 AEO70289.1 - 0.032 13.3 0.0 0.074 12.1 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 AEO70289.1 - 0.041 13.1 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 AEO70289.1 - 0.05 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AEO70289.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AEO70289.1 - 0.071 12.9 0.0 0.24 11.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 AEO70289.1 - 0.081 13.2 0.3 0.18 12.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.1 AEO70289.1 - 0.17 11.4 0.2 0.3 10.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 AEO70289.1 - 0.18 10.7 0.0 0.31 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PPV_E1_C PF00519.12 AEO70289.1 - 0.27 9.8 0.0 0.41 9.2 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase SH3BGR PF04908.10 AEO70290.1 - 4.4e-05 23.3 0.0 0.00012 21.9 0.0 1.8 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein DNA_pol_viral_N PF00242.12 AEO70290.1 - 9.5 5.1 12.5 15 4.4 8.7 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF3827 PF12877.2 AEO70291.1 - 0.017 13.2 5.9 0.02 13.0 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Zip PF02535.17 AEO70291.1 - 0.097 11.6 11.7 0.12 11.3 8.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Hepcidin PF06446.7 AEO70291.1 - 0.22 11.9 0.3 0.22 11.9 0.2 3.3 3 1 0 3 3 3 0 Hepcidin Macoilin PF09726.4 AEO70291.1 - 0.23 9.7 7.5 0.3 9.3 5.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Hid1 PF12722.2 AEO70291.1 - 1 6.9 7.0 1.3 6.5 4.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-RING_2 PF13639.1 AEO70293.1 - 1.8e-09 37.2 12.3 9e-09 35.0 3.7 2.4 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.20 AEO70293.1 - 5.9e-05 22.6 2.8 5.9e-05 22.6 1.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO70293.1 - 0.00037 20.4 8.7 0.0024 17.8 3.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO70293.1 - 0.0042 17.1 11.7 0.055 13.5 6.0 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger Rad50_zn_hook PF04423.9 AEO70293.1 - 0.014 14.8 0.1 0.014 14.8 0.1 1.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_5 PF14634.1 AEO70293.1 - 0.14 11.8 8.4 5.1 6.9 3.3 2.4 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 AEO70293.1 - 0.15 11.7 8.6 3 7.6 3.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AEO70293.1 - 0.16 11.8 7.3 0.082 12.7 1.9 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Vps39_2 PF10367.4 AEO70293.1 - 0.27 11.4 0.0 0.27 11.4 0.0 1.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.1 AEO70293.1 - 0.72 9.6 7.2 0.12 12.1 1.4 2.1 2 0 0 2 2 2 0 RING-type zinc-finger Zn-ribbon_8 PF09723.5 AEO70293.1 - 1.5 8.8 5.0 5.9 6.9 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain FANCL_C PF11793.3 AEO70293.1 - 3.4 7.6 8.9 7.4 6.6 4.1 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 AEO70293.1 - 3.6 7.7 8.9 6.7 6.8 4.5 2.3 2 0 0 2 2 2 0 RING-variant domain Prok-RING_1 PF14446.1 AEO70293.1 - 4.8 7.0 9.8 13 5.6 4.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 AEO70293.1 - 6.7 6.3 9.5 4.5 6.9 2.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain dCMP_cyt_deam_1 PF00383.17 AEO70294.1 - 2.9e-10 39.6 2.9 1.7e-09 37.2 2.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 AEO70294.1 - 1.7e-05 24.8 2.0 0.00069 19.6 0.4 2.8 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 AEO70294.1 - 0.0011 18.4 1.2 0.39 10.0 0.2 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases zf-SNAP50_C PF12251.3 AEO70294.1 - 0.05 12.9 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Macoilin PF09726.4 AEO70295.1 - 2.4 6.3 4.8 2.5 6.2 3.3 1.1 1 0 0 1 1 1 0 Transmembrane protein MGC-24 PF05283.6 AEO70295.1 - 3.8 7.2 21.0 6.1 6.5 14.5 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Opi1 PF08618.5 AEO70295.1 - 8.9 5.1 17.8 2.1 7.1 7.8 2.0 2 0 0 2 2 2 0 Transcription factor Opi1 Alpha_GJ PF03229.8 AEO70295.1 - 9.3 6.6 19.6 14 6.0 12.4 2.3 1 1 1 2 2 2 0 Alphavirus glycoprotein J Glyco_hydro_47 PF01532.15 AEO70296.1 - 3.2e-161 536.9 0.0 3.7e-161 536.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 AEO70296.1 - 0.059 11.6 0.0 0.67 8.1 0.0 2.2 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) ABC_membrane PF00664.18 AEO70297.1 - 1.5e-76 257.4 37.5 2.2e-40 138.7 6.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AEO70297.1 - 3.7e-61 205.3 0.3 1e-31 110.0 0.0 3.3 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AEO70297.1 - 5.2e-13 49.6 1.3 0.0094 15.9 0.1 4.3 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 AEO70297.1 - 2.1e-10 40.2 8.2 0.00017 20.9 1.6 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 AEO70297.1 - 9.5e-09 34.3 0.5 0.0041 15.7 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 AEO70297.1 - 2.5e-08 34.1 2.9 0.0002 21.3 0.0 3.8 4 0 0 4 4 3 2 AAA ATPase domain AAA_29 PF13555.1 AEO70297.1 - 7.7e-08 31.7 2.2 0.00098 18.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF3987 PF13148.1 AEO70297.1 - 9.9e-08 30.9 0.4 9.9e-07 27.6 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_17 PF13207.1 AEO70297.1 - 4.7e-07 30.6 0.3 0.059 14.1 0.1 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 AEO70297.1 - 7.1e-06 25.2 0.2 0.085 12.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 AEO70297.1 - 3.2e-05 24.0 1.0 0.38 10.8 0.1 3.8 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.1 AEO70297.1 - 6.8e-05 22.5 1.2 0.72 9.3 0.0 4.1 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.1 AEO70297.1 - 0.0001 22.1 1.7 0.18 11.7 0.1 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 AEO70297.1 - 0.00036 19.7 1.3 0.05 12.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 AEO70297.1 - 0.00036 20.0 1.7 0.021 14.2 0.0 3.4 3 0 0 3 3 3 1 AAA-like domain AAA_25 PF13481.1 AEO70297.1 - 0.00046 19.6 1.3 0.77 9.1 0.2 3.6 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 AEO70297.1 - 0.0012 19.1 0.4 2.4 8.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 AEO70297.1 - 0.0026 17.4 0.1 2.2 8.0 0.0 3.2 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AEO70297.1 - 0.004 17.0 0.4 0.55 10.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 AEO70297.1 - 0.0049 17.2 7.4 0.72 10.1 2.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.1 AEO70297.1 - 0.031 14.2 0.2 9.4 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain BLVR PF06375.6 AEO70297.1 - 0.032 14.0 3.7 0.066 13.0 2.5 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF87 PF01935.12 AEO70297.1 - 0.042 13.6 1.4 1.6 8.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 ATP_bind_1 PF03029.12 AEO70297.1 - 0.043 13.3 0.1 5 6.5 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.9 AEO70297.1 - 0.075 12.7 2.4 4.5 6.9 0.5 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 AEO70297.1 - 0.15 11.5 1.2 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family tRNA-synt_His PF13393.1 AEO70298.1 - 3.2e-41 141.3 0.0 5.6e-35 120.8 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 AEO70298.1 - 2.1e-18 66.4 0.0 3.6e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AEO70298.1 - 5.2e-13 48.7 0.0 9.1e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 AEO70298.1 - 2.5e-05 23.1 0.1 0.0028 16.4 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) Pkinase PF00069.20 AEO70300.1 - 1.6e-70 237.2 0.0 2.1e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO70300.1 - 7.5e-34 116.9 0.0 1.3e-33 116.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO70300.1 - 7.3e-05 21.8 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 AEO70300.1 - 0.0021 17.4 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 AEO70300.1 - 0.0024 16.9 0.2 0.0048 15.9 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO70300.1 - 0.032 13.9 0.5 0.42 10.2 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family UQ_con PF00179.21 AEO70301.1 - 9.6e-26 89.8 0.0 1.1e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO70301.1 - 8.7e-07 28.7 0.0 1.9e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AEO70301.1 - 0.0015 18.4 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 AEO70301.1 - 0.0063 16.1 0.1 0.0088 15.7 0.1 1.2 1 0 0 1 1 1 1 UEV domain UFC1 PF08694.6 AEO70301.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Sec1 PF00995.18 AEO70302.1 - 8.1e-140 467.1 0.0 9.2e-140 466.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family UPF0167 PF03691.9 AEO70302.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) zf-ZPR1 PF03367.8 AEO70302.1 - 0.15 11.2 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Amino_oxidase PF01593.19 AEO70303.1 - 1.6e-90 304.3 0.0 3.3e-90 303.3 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 AEO70303.1 - 1.8e-10 40.7 0.0 3.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain HMG_box PF00505.14 AEO70303.1 - 3.4e-07 30.4 6.2 3.7e-07 30.3 0.9 2.8 2 1 0 2 2 2 1 HMG (high mobility group) box NAD_binding_8 PF13450.1 AEO70303.1 - 5.4e-07 29.5 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box_2 PF09011.5 AEO70303.1 - 1.2e-05 25.5 0.5 1.2e-05 25.5 0.3 2.2 2 0 0 2 2 2 1 HMG-box domain DAO PF01266.19 AEO70303.1 - 0.0077 15.1 0.1 0.093 11.6 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Nucleo_P87 PF07267.6 AEO70303.1 - 0.028 13.1 4.4 0.044 12.4 3.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 AlaDh_PNT_C PF01262.16 AEO70303.1 - 0.035 13.6 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 AEO70303.1 - 0.048 13.5 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO70303.1 - 0.053 13.5 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cpn60_TCP1 PF00118.19 AEO70303.1 - 0.4 9.2 0.0 5 5.6 0.0 2.0 2 0 0 2 2 2 0 TCP-1/cpn60 chaperonin family HI0933_like PF03486.9 AEO70303.1 - 0.52 8.7 0.1 2.3 6.6 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein ATP-synt PF00231.14 AEO70304.1 - 1.7e-69 234.3 0.6 2e-69 234.1 0.4 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I_N PF02919.10 AEO70305.1 - 6.4e-100 332.8 3.9 6.4e-100 332.8 2.7 2.8 5 0 0 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 AEO70305.1 - 1.5e-85 286.0 6.3 3.4e-85 284.8 4.3 1.5 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core DUF2570 PF10828.3 AEO70305.1 - 0.053 13.1 0.4 0.37 10.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Glyco_hydro_16 PF00722.16 AEO70306.1 - 1.3e-44 151.6 0.7 2.8e-44 150.6 0.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Collagen PF01391.13 AEO70307.1 - 0.00019 20.8 2.6 0.036 13.6 0.2 3.1 3 0 0 3 3 3 2 Collagen triple helix repeat (20 copies) SLAC1 PF03595.12 AEO70308.1 - 0.0082 14.8 0.1 0.011 14.4 0.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Intg_mem_TP0381 PF09529.5 AEO70308.1 - 0.027 13.7 0.3 0.032 13.4 0.2 1.1 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) 7TMR-DISM_7TM PF07695.6 AEO70308.1 - 0.036 13.7 0.5 0.039 13.6 0.3 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF4131 PF13567.1 AEO70308.1 - 0.35 10.2 3.1 0.29 10.5 0.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF1275 PF06912.6 AEO70309.1 - 0.0044 16.2 5.8 0.0061 15.7 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF3784 PF12650.2 AEO70309.1 - 3.2 7.7 8.1 0.43 10.5 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) Aminotran_1_2 PF00155.16 AEO70310.1 - 2.6e-18 66.1 0.0 3.3e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 AEO70310.1 - 2e-07 29.9 0.0 3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase p450 PF00067.17 AEO70311.1 - 3.3e-61 207.2 0.0 4.9e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_20 PF00728.17 AEO70312.1 - 2.9e-85 286.5 0.0 3.5e-85 286.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 AEO70312.1 - 5.3e-26 91.7 0.0 9.2e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 AEO70312.1 - 3.8e-08 33.9 0.0 1.5e-07 31.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 zf-CCCH_2 PF14608.1 AEO70313.1 - 2.8e-06 27.0 57.9 3.6e-06 26.7 8.0 5.5 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Neur_chan_memb PF02932.11 AEO70313.1 - 4.8 6.9 5.8 1.2 9.0 1.9 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Amino_oxidase PF01593.19 AEO70314.1 - 8e-14 51.5 0.3 7.9e-07 28.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 AEO70314.1 - 5.8e-10 39.0 0.1 1.7e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO70314.1 - 1.4e-07 30.8 0.0 3.2e-06 26.3 0.0 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO70314.1 - 0.0018 18.6 0.0 0.096 13.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO70314.1 - 0.035 13.8 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 AEO70314.1 - 0.05 12.5 0.0 0.33 9.7 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Med14 PF08638.6 AEO70315.1 - 9.8e-69 230.5 0.0 1.6e-68 229.8 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 PAT1 PF09770.4 AEO70315.1 - 4.7 5.3 25.4 7.6 4.6 17.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 G6PD_C PF02781.11 AEO70316.1 - 1e-129 431.5 0.0 1.5e-129 431.0 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 AEO70316.1 - 2.8e-63 213.4 0.0 4.6e-63 212.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Ribosomal_L35Ae PF01247.13 AEO70317.1 - 2.3e-43 145.9 0.6 2.5e-43 145.7 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 AEO70317.1 - 0.00031 20.6 0.1 0.19 11.6 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF3703 PF12487.3 AEO70317.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3703) DUF2406 PF10295.4 AEO70318.1 - 1.1e-22 80.2 1.1 2.2e-22 79.3 0.1 2.0 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) VMA21 PF09446.5 AEO70319.1 - 1.3e-15 57.0 7.4 1.8e-15 56.5 5.1 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF4282 PF14110.1 AEO70319.1 - 3.1 8.0 6.3 4.4 7.5 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) SNF2_N PF00176.18 AEO70320.1 - 1.6e-58 197.8 0.0 2.2e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO70320.1 - 1.1e-14 54.0 0.1 2.2e-13 49.8 0.0 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF3336 PF11815.3 AEO70321.1 - 2.5e-34 117.8 0.0 2.4e-33 114.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 AEO70321.1 - 4.4e-14 52.9 0.0 8.1e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase SMN PF06003.7 AEO70322.1 - 2.3 7.2 6.7 4.4 6.3 4.5 1.6 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) Lipase_GDSL_2 PF13472.1 AEO70323.1 - 2.5e-17 63.6 3.2 2.5e-17 63.6 2.2 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO70323.1 - 1.9e-16 60.5 0.1 1.8e-15 57.4 0.1 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase BOP1NT PF08145.7 AEO70324.1 - 1.2e-103 346.4 8.7 1.8e-103 345.7 6.0 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 AEO70324.1 - 4.8e-28 96.0 5.6 1.3e-10 40.7 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat SURF4 PF02077.10 AEO70326.1 - 5.6e-97 324.2 7.2 6.4e-97 324.1 5.0 1.0 1 0 0 1 1 1 1 SURF4 family Halogen_Hydrol PF10112.4 AEO70326.1 - 1.5 8.1 6.3 4.4 6.6 0.4 3.1 3 1 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Peptidase_A24 PF01478.13 AEO70326.1 - 1.8 8.8 14.5 1.9 8.7 0.6 2.7 2 1 0 2 2 2 0 Type IV leader peptidase family FA_desaturase PF00487.19 AEO70326.1 - 4.4 6.6 9.2 6.9 6.0 5.3 2.0 1 1 0 1 1 1 0 Fatty acid desaturase VSP PF03302.8 AEO70327.1 - 0.26 9.8 2.3 0.44 9.1 1.6 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DAP10 PF07213.6 AEO70327.1 - 4.9 6.9 8.1 0.61 9.8 2.1 2.1 2 0 0 2 2 2 0 DAP10 membrane protein Yip1 PF04893.12 AEO70327.1 - 6.9 6.1 11.1 0.8 9.1 3.3 2.2 2 1 0 2 2 2 0 Yip1 domain Alg6_Alg8 PF03155.10 AEO70328.1 - 1.7e-130 436.0 24.1 4.6e-82 276.3 5.8 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family DUF2975 PF11188.3 AEO70328.1 - 7.4 6.2 18.6 1.6 8.4 4.6 3.5 3 2 1 4 4 4 0 Protein of unknown function (DUF2975) BRO1 PF03097.13 AEO70329.1 - 0.00015 20.6 0.1 0.00024 19.9 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain Serglycin PF04360.7 AEO70329.1 - 0.15 11.7 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Serglycin Leo1 PF04004.8 AEO70330.1 - 8e-32 110.2 0.0 8e-32 110.2 0.0 2.0 2 0 0 2 2 2 1 Leo1-like protein Mob1_phocein PF03637.12 AEO70331.1 - 7.3e-36 123.4 2.0 2.4e-17 63.1 0.5 2.2 2 0 0 2 2 2 2 Mob1/phocein family OSTMP1 PF09777.4 AEO70331.1 - 0.017 14.3 0.1 0.026 13.7 0.1 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor DUF3237 PF11578.3 AEO70332.1 - 8.7e-25 86.7 0.0 1e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) CorA PF01544.13 AEO70333.1 - 5.5e-41 140.5 1.5 5.8e-40 137.1 1.0 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CSTF2_hinge PF14327.1 AEO70334.1 - 4.7e-31 106.7 1.0 4.7e-31 106.7 0.7 1.6 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 AEO70334.1 - 1.3e-22 79.2 0.0 2.1e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO70334.1 - 1.6e-18 66.4 0.0 3.4e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO70334.1 - 6.6e-06 25.8 0.0 9.7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 AEO70334.1 - 4.9e-05 22.5 4.2 4.9e-05 22.5 2.9 2.7 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal DUF3135 PF11333.3 AEO70334.1 - 0.74 10.0 2.8 0.7 10.0 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) Band_7 PF01145.20 AEO70335.1 - 8.4e-26 90.9 1.6 1.2e-25 90.4 1.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family ubiquitin PF00240.18 AEO70336.1 - 1.8e-25 88.1 0.1 2e-25 87.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 AEO70336.1 - 3.7e-14 52.1 0.0 4.3e-14 51.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AEO70336.1 - 0.003 17.7 0.1 0.0075 16.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain Elongin_A PF06881.6 AEO70337.1 - 2e-15 57.1 0.5 2e-15 57.1 0.3 1.6 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ACC_epsilon PF13822.1 AEO70337.1 - 0.17 12.2 0.3 0.17 12.2 0.2 3.2 3 1 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit LAT PF15234.1 AEO70337.1 - 3.3 7.1 13.5 0.094 12.1 0.8 2.6 1 1 1 2 2 2 0 Linker for activation of T-cells THOC7 PF05615.8 AEO70338.1 - 5.4e-44 149.8 0.1 5.4e-44 149.8 0.0 2.0 2 0 0 2 2 2 1 Tho complex subunit 7 ATG16 PF08614.6 AEO70338.1 - 0.0013 18.6 6.2 0.3 10.9 0.3 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Methyltransf_26 PF13659.1 AEO70338.1 - 0.033 14.2 1.5 0.054 13.5 1.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RTBV_P46 PF06216.6 AEO70338.1 - 0.061 12.1 2.4 0.077 11.8 0.7 1.6 1 1 0 2 2 2 0 Rice tungro bacilliform virus P46 protein MSA-2c PF12238.3 AEO70338.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.2 2 0 0 2 2 2 0 Merozoite surface antigen 2c zf-C4H2 PF10146.4 AEO70338.1 - 0.21 11.5 8.8 0.39 10.7 0.5 2.8 1 1 1 3 3 3 0 Zinc finger-containing protein AAA_13 PF13166.1 AEO70338.1 - 0.85 7.9 2.7 2.4 6.5 1.9 1.6 1 1 0 1 1 1 0 AAA domain APG6 PF04111.7 AEO70338.1 - 1.6 7.7 5.7 2.7 6.9 3.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2664 PF10867.3 AEO70338.1 - 3.7 8.2 8.4 0.55 10.8 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) Mnd1 PF03962.10 AEO70338.1 - 4.8 6.7 8.3 4.4 6.9 0.3 2.3 1 1 2 3 3 3 0 Mnd1 family FUSC PF04632.7 AEO70338.1 - 6.8 4.9 18.1 9.7 4.4 12.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TBCA PF02970.11 AEO70339.1 - 1e-18 67.1 11.3 1.4e-18 66.7 7.6 1.4 1 1 0 1 1 1 1 Tubulin binding cofactor A Flagellin_C PF00700.16 AEO70339.1 - 0.04 14.0 0.3 0.54 10.4 0.0 2.3 2 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region CALCOCO1 PF07888.6 AEO70339.1 - 0.052 11.8 9.1 0.059 11.6 6.3 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2972 PF11186.3 AEO70339.1 - 0.068 13.0 3.2 0.13 12.1 2.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2972) DUF4404 PF14357.1 AEO70339.1 - 0.27 11.6 6.4 0.87 10.0 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) XhlA PF10779.4 AEO70339.1 - 0.42 10.5 10.4 1.9 8.4 2.1 2.3 1 1 1 2 2 2 0 Haemolysin XhlA Tropomyosin PF00261.15 AEO70339.1 - 0.52 9.3 16.8 0.77 8.8 5.8 2.0 1 1 1 2 2 2 0 Tropomyosin Plasmid_stabil PF05016.9 AEO70339.1 - 0.63 10.4 3.9 10 6.5 0.2 2.4 1 1 1 2 2 2 0 Plasmid stabilisation system protein IncA PF04156.9 AEO70339.1 - 0.84 9.1 9.5 1.1 8.7 6.6 1.1 1 0 0 1 1 1 0 IncA protein AAA_13 PF13166.1 AEO70339.1 - 1.9 6.8 11.0 2.9 6.2 7.6 1.3 1 1 0 1 1 1 0 AAA domain OmpH PF03938.9 AEO70339.1 - 2.3 8.1 14.4 8.7 6.2 9.9 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ADIP PF11559.3 AEO70339.1 - 3.5 7.5 13.0 2.5 8.0 1.5 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding RRF PF01765.14 AEO70339.1 - 4.8 6.6 9.7 0.25 10.7 1.8 1.9 1 1 1 2 2 2 0 Ribosome recycling factor TPR_MLP1_2 PF07926.7 AEO70339.1 - 6.5 6.5 14.6 3.4e+02 0.9 10.1 2.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein E1-E2_ATPase PF00122.15 AEO70340.1 - 7.4e-64 214.9 7.4 1.1e-62 211.1 4.4 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AEO70340.1 - 1.1e-45 155.3 6.6 1.1e-45 155.3 4.6 1.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AEO70340.1 - 2.2e-33 116.4 0.0 1.7e-32 113.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO70340.1 - 6.7e-23 80.4 0.0 1.3e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 AEO70340.1 - 5.2e-21 73.8 0.0 1.6e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 AEO70340.1 - 2.3e-18 67.0 0.0 6.6e-18 65.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AEO70340.1 - 1.5e-09 37.8 1.0 5.5e-06 26.1 0.7 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AEO70340.1 - 0.0023 18.1 0.0 0.0091 16.2 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Proteasome PF00227.21 AEO70341.1 - 1.7e-40 138.3 0.0 1.9e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.3 AEO70342.1 - 4.6e-25 87.3 0.1 1.3e-24 85.8 0.0 1.9 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBX PF00789.15 AEO70342.1 - 0.00012 22.0 0.0 0.0005 20.0 0.0 2.1 2 0 0 2 2 2 1 UBX domain RBD PF02196.10 AEO70342.1 - 0.015 15.0 0.2 0.042 13.5 0.2 1.7 1 0 0 1 1 1 0 Raf-like Ras-binding domain Chalcone PF02431.10 AEO70342.1 - 0.065 12.6 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 Chalcone-flavanone isomerase DUF3127 PF11325.3 AEO70342.1 - 0.1 12.6 0.0 0.43 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3127) Lipase_3 PF01764.20 AEO70344.1 - 1.6e-29 102.3 0.0 2.2e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 AEO70344.1 - 0.00037 20.2 0.0 0.00067 19.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO70344.1 - 0.00083 19.2 0.1 0.00083 19.2 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 AEO70344.1 - 0.051 12.9 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.3 AEO70344.1 - 0.063 12.6 0.3 0.53 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 AEO70344.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 AEO70344.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold 14-3-3 PF00244.15 AEO70345.1 - 1.5e-114 380.9 0.9 1.9e-114 380.6 0.6 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 AEO70345.1 - 0.0028 17.2 0.8 1.2 8.5 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF837) TPR_12 PF13424.1 AEO70345.1 - 0.035 14.0 0.5 10 6.1 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Syja_N PF02383.13 AEO70347.1 - 5.1e-85 285.0 0.0 8.2e-85 284.3 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 AEO70347.1 - 6.4e-26 91.7 0.1 1.1e-25 91.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_16 PF13432.1 AEO70348.1 - 1e-05 26.0 1.2 0.039 14.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Suf PF05843.9 AEO70348.1 - 0.0014 18.3 2.8 0.4 10.3 0.0 3.2 2 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 AEO70348.1 - 0.0018 18.7 3.8 0.29 11.8 0.1 5.2 5 1 1 6 6 6 1 Tetratricopeptide repeat HTS PF04204.11 AEO70348.1 - 0.04 12.6 5.7 0.052 12.2 0.5 2.4 2 0 0 2 2 2 0 Homoserine O-succinyltransferase peroxidase PF00141.18 AEO70349.1 - 1.6e-49 168.5 0.0 2.5e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Peroxidase ATP11 PF06644.6 AEO70350.1 - 4.1e-78 262.5 0.0 5.9e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 ATP11 protein AMP-binding PF00501.23 AEO70351.1 - 2.6e-93 312.6 0.0 3.2e-93 312.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO70351.1 - 1e-14 55.2 0.8 2.6e-14 53.9 0.5 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Med15 PF09606.5 AEO70353.1 - 0.12 10.5 18.4 0.19 9.9 12.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Cadherin_C PF01049.12 AEO70354.1 - 0.096 12.7 1.2 0.11 12.4 0.4 1.4 2 0 0 2 2 2 0 Cadherin cytoplasmic region PX PF00787.19 AEO70354.1 - 0.15 11.8 0.9 0.21 11.4 0.6 1.4 1 1 0 1 1 1 0 PX domain AA_permease PF00324.16 AEO70356.1 - 1.3e-123 412.8 31.3 3.3e-123 411.5 21.7 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO70356.1 - 3.4e-33 114.8 30.5 4.3e-33 114.4 21.2 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_47 PF01532.15 AEO70357.1 - 8.3e-160 532.3 0.0 1.1e-159 531.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.1 AEO70357.1 - 0.0041 16.5 0.1 0.0081 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) RRM_5 PF13893.1 AEO70360.1 - 5.9e-10 38.8 0.0 8.7e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO70360.1 - 9.4e-09 34.7 0.0 2.4e-08 33.4 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO70360.1 - 0.0001 22.2 0.0 0.0002 21.2 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 AEO70360.1 - 0.0005 19.7 0.0 0.00099 18.7 0.0 1.5 1 0 0 1 1 1 1 Calcipressin WD40 PF00400.27 AEO70361.1 - 1.7e-20 72.0 9.8 2.6e-08 33.4 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Rax2 PF12768.2 AEO70361.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity PD40 PF07676.7 AEO70361.1 - 0.048 13.3 0.0 20 4.9 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Carla_C4 PF01623.12 AEO70363.1 - 0.078 12.7 0.3 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein REV PF00424.13 AEO70363.1 - 4.5 7.2 10.1 0.19 11.6 0.6 2.1 1 1 1 2 2 2 0 REV protein (anti-repression trans-activator protein) Phosphoesterase PF04185.9 AEO70364.1 - 1.5e-36 126.4 4.7 4.3e-36 124.9 3.2 1.6 1 1 0 1 1 1 1 Phosphoesterase family Nse5 PF08691.5 AEO70364.1 - 0.093 11.2 0.1 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 Cu-oxidase_3 PF07732.10 AEO70365.1 - 1.1e-42 144.4 0.6 1.1e-42 144.4 0.4 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 AEO70365.1 - 3e-37 127.9 0.7 3e-37 127.9 0.5 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 AEO70365.1 - 6.5e-36 122.8 5.1 3.6e-32 110.7 0.1 3.7 3 1 0 3 3 3 2 Multicopper oxidase SBDS PF01172.13 AEO70366.1 - 6.8e-28 96.3 0.1 7.9e-28 96.0 0.0 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF2857 PF11198.3 AEO70366.1 - 0.089 12.3 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) RhoGEF PF00621.15 AEO70367.1 - 4.9e-16 59.1 0.0 8.1e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain GRASP55_65 PF04495.9 AEO70368.1 - 2.7e-06 27.4 0.0 6.6e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 AEO70368.1 - 5.9e-06 26.0 0.0 1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 AEO70368.1 - 0.00077 19.5 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Ras PF00071.17 AEO70369.1 - 2.1e-49 166.9 0.0 2.6e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO70369.1 - 8.6e-16 58.5 0.0 1.6e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO70369.1 - 1.5e-10 40.5 0.0 1.9e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 AEO70369.1 - 0.00075 19.6 0.1 0.0041 17.2 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 AEO70369.1 - 0.0015 17.6 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 AEO70369.1 - 0.025 13.8 0.1 0.043 13.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_33 PF13671.1 AEO70369.1 - 0.081 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 AEO70369.1 - 0.082 12.1 0.0 0.14 11.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 AEO70369.1 - 0.082 13.0 0.1 0.23 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 AEO70369.1 - 0.099 11.7 0.2 0.15 11.1 0.2 1.2 1 0 0 1 1 1 0 KaiC G-alpha PF00503.15 AEO70369.1 - 0.12 11.0 3.2 1.1 7.8 0.1 2.5 2 1 1 3 3 3 0 G-protein alpha subunit STAS PF01740.16 AEO70369.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 STAS domain WSC PF01822.14 AEO70370.1 - 4.5e-91 298.8 86.9 8.8e-19 67.2 8.9 5.3 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.6 AEO70370.1 - 9.5e-25 87.0 0.0 1.8e-23 82.9 0.0 2.7 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 AEO70370.1 - 4e-20 71.7 0.0 7.9e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) bZIP_1 PF00170.16 AEO70371.1 - 0.00065 19.6 6.8 0.00065 19.6 4.7 2.0 1 1 1 2 2 2 1 bZIP transcription factor HALZ PF02183.13 AEO70371.1 - 0.013 15.2 0.2 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Spt5_N PF11942.3 AEO70371.1 - 0.41 11.2 3.1 0.58 10.8 2.1 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal bZIP_Maf PF03131.12 AEO70371.1 - 0.42 10.9 7.5 0.62 10.3 5.2 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor PV-1 PF06637.6 AEO70371.1 - 1.1 7.7 6.7 1.5 7.3 4.6 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) RRN3 PF05327.6 AEO70372.1 - 6.8e-158 526.2 0.0 6.8e-158 526.2 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 CBFD_NFYB_HMF PF00808.18 AEO70373.1 - 3.2e-29 100.7 1.0 4.2e-29 100.3 0.7 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AEO70373.1 - 3.3e-07 30.3 0.1 5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 AEO70373.1 - 0.0012 18.6 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 AEO70373.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 AEO70373.1 - 0.048 13.9 0.0 0.083 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.15 AEO70374.1 - 3.6e-26 90.9 6.0 4.1e-26 90.8 4.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF2205 PF10224.4 AEO70374.1 - 0.003 17.0 6.6 0.14 11.7 0.4 2.1 2 0 0 2 2 2 2 Predicted coiled-coil protein (DUF2205) Prefoldin PF02996.12 AEO70374.1 - 0.02 14.5 5.6 0.33 10.5 0.1 2.1 1 1 2 3 3 3 0 Prefoldin subunit Mnd1 PF03962.10 AEO70374.1 - 0.04 13.5 2.3 0.068 12.8 1.6 1.4 1 1 0 1 1 1 0 Mnd1 family p25-alpha PF05517.7 AEO70374.1 - 0.04 14.1 0.7 2.3 8.4 0.0 2.0 2 0 0 2 2 2 0 p25-alpha DUF148 PF02520.12 AEO70374.1 - 0.047 13.4 4.2 0.32 10.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 DUF641 PF04859.7 AEO70374.1 - 0.063 13.0 2.7 0.17 11.6 0.2 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TPR_MLP1_2 PF07926.7 AEO70374.1 - 0.065 12.9 6.8 0.23 11.2 0.1 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3166 PF11365.3 AEO70374.1 - 0.066 13.6 2.1 5.4 7.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) HrpB7 PF09486.5 AEO70374.1 - 0.075 12.9 1.5 3.3 7.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) IncA PF04156.9 AEO70374.1 - 0.085 12.4 4.5 0.19 11.2 3.1 1.5 1 1 0 1 1 1 0 IncA protein Tho2 PF11262.3 AEO70374.1 - 0.086 11.8 0.5 0.67 8.9 0.4 1.9 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF2956 PF11169.3 AEO70374.1 - 0.088 12.7 0.7 0.088 12.7 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Syntaxin-6_N PF09177.6 AEO70374.1 - 0.12 12.7 1.3 11 6.5 0.2 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF4200 PF13863.1 AEO70374.1 - 0.18 11.7 4.4 0.52 10.2 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FliJ PF02050.11 AEO70374.1 - 0.19 11.7 6.7 2.9 7.9 1.2 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Snf7 PF03357.16 AEO70374.1 - 0.2 11.0 3.6 1 8.7 0.3 2.1 2 0 0 2 2 2 0 Snf7 GAS PF13851.1 AEO70374.1 - 0.26 10.4 6.9 0.7 9.0 4.8 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 AEO70374.1 - 0.31 9.9 2.7 0.42 9.5 1.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc24 PF08286.6 AEO70374.1 - 0.4 10.3 5.2 1.4 8.6 0.6 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Cytochrom_B562 PF07361.6 AEO70374.1 - 0.46 10.9 4.7 1.3 9.5 0.6 2.1 2 0 0 2 2 2 0 Cytochrome b562 DASH_Dad3 PF08656.5 AEO70374.1 - 0.49 10.1 4.2 0.46 10.2 1.1 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 TMF_DNA_bd PF12329.3 AEO70374.1 - 0.91 9.3 7.0 1 9.2 1.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_Maf PF03131.12 AEO70374.1 - 1.5 9.1 5.8 6.8 7.0 0.1 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor Rho_Binding PF08912.6 AEO70374.1 - 9.6 6.5 8.5 1.3 9.3 1.1 2.3 2 0 0 2 2 2 0 Rho Binding Cmc1 PF08583.5 AEO70375.1 - 6.8e-16 57.7 3.2 8.5e-16 57.4 2.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like MobA_MobL PF03389.10 AEO70375.1 - 0.065 12.6 0.6 0.079 12.3 0.4 1.0 1 0 0 1 1 1 0 MobA/MobL family zf-C2H2 PF00096.21 AEO70376.1 - 2.4e-06 27.5 20.3 0.00094 19.3 0.2 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO70376.1 - 0.018 15.3 0.7 0.018 15.3 0.5 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger TRP PF06011.7 AEO70377.1 - 5.6e-134 447.0 22.3 7.4e-134 446.6 15.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 AEO70377.1 - 7.4e-40 136.2 5.2 1.3e-39 135.4 3.6 1.4 1 0 0 1 1 1 1 ML-like domain Abhydrolase_6 PF12697.2 AEO70378.1 - 3e-16 59.9 6.0 9.1e-16 58.4 4.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO70378.1 - 0.00018 21.2 0.1 0.00046 19.9 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO70378.1 - 0.082 12.4 0.0 4.4 6.7 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Dus PF01207.12 AEO70379.1 - 2.4e-41 141.5 1.4 2.5e-40 138.2 1.0 2.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) FCP1_C PF09309.5 AEO70379.1 - 0.015 14.5 6.6 0.045 13.0 4.8 1.5 2 0 0 2 2 2 0 FCP1, C-terminal GAGA_bind PF06217.7 AEO70379.1 - 0.091 12.7 3.9 0.13 12.1 2.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2201_N PF13203.1 AEO70379.1 - 0.12 11.5 6.2 0.23 10.5 4.3 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain DDHD PF02862.12 AEO70379.1 - 0.94 9.2 3.9 1.4 8.6 2.7 1.2 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 AEO70379.1 - 1.9 8.3 8.3 2.9 7.7 5.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 AEO70379.1 - 3.6 5.1 3.9 4.7 4.7 2.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2058 PF09831.4 AEO70379.1 - 4.9 6.9 14.5 7.6 6.3 10.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Med19 PF10278.4 AEO70379.1 - 8.4 6.0 11.6 13 5.4 8.0 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Macoilin PF09726.4 AEO70380.1 - 0.12 10.6 2.1 0.12 10.6 1.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Zip PF02535.17 AEO70380.1 - 1.8 7.5 3.6 1.8 7.4 2.5 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Gyro_capsid PF04162.7 AEO70380.1 - 7.4 4.6 9.3 7.9 4.5 6.4 1.0 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) HAMP PF00672.20 AEO70382.1 - 1.5e-49 166.0 16.7 2.9e-10 40.1 0.2 7.4 6 1 1 7 7 7 6 HAMP domain HATPase_c PF02518.21 AEO70382.1 - 2.4e-29 101.3 0.9 6.1e-29 99.9 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 AEO70382.1 - 4.9e-27 94.1 0.5 3.5e-26 91.4 0.2 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 AEO70382.1 - 4.1e-18 65.1 0.5 4.1e-18 65.1 0.4 4.3 5 0 0 5 5 5 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.1 AEO70382.1 - 0.0017 16.9 19.5 0.075 11.4 0.1 3.9 1 1 3 4 4 4 4 AAA domain NAAA-beta PF15508.1 AEO70382.1 - 0.16 12.3 5.0 9.2 6.6 0.1 5.6 4 2 3 7 7 7 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF2365 PF10157.4 AEO70382.1 - 0.21 11.4 15.6 3.7 7.4 0.0 6.8 6 1 2 8 8 8 0 Uncharacterized conserved protein (DUF2365) DUF883 PF05957.8 AEO70382.1 - 5.8 7.3 25.6 0.98 9.8 0.1 6.7 6 1 1 7 7 7 0 Bacterial protein of unknown function (DUF883) HMG_box PF00505.14 AEO70383.1 - 8.2e-16 58.0 0.1 1.8e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AEO70383.1 - 4.5e-14 52.5 0.1 9.1e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 AEO70383.1 - 1.2e-11 44.6 0.0 2.2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 AEO70383.1 - 1.9e-09 37.1 0.0 3.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) OEP PF02321.13 AEO70384.1 - 0.035 13.6 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein PNRC PF15365.1 AEO70384.1 - 0.11 12.5 0.5 0.16 11.9 0.3 1.4 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator Cnd2 PF05786.9 AEO70385.1 - 8.7e-215 715.4 2.0 1.2e-214 714.9 1.4 1.2 1 0 0 1 1 1 1 Condensin complex subunit 2 Na_Ca_ex PF01699.19 AEO70386.1 - 3e-45 153.2 34.4 5e-23 81.2 3.4 3.3 2 1 1 3 3 3 3 Sodium/calcium exchanger protein PMM PF03332.8 AEO70387.1 - 8.1e-103 342.7 0.1 9.5e-103 342.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 AEO70387.1 - 0.0059 16.2 0.0 0.12 11.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase LGFP PF08310.6 AEO70387.1 - 0.088 12.4 1.0 22 4.8 0.1 3.2 2 2 0 2 2 2 0 LGFP repeat WW PF00397.21 AEO70388.1 - 9.1e-10 38.2 0.4 3.2e-09 36.4 0.1 2.2 2 0 0 2 2 2 1 WW domain PhoD PF09423.5 AEO70388.1 - 0.093 11.2 1.3 0.28 9.7 0.6 1.8 2 0 0 2 2 2 0 PhoD-like phosphatase MFS_1 PF07690.11 AEO70389.1 - 1.7e-08 33.5 14.2 1.7e-08 33.5 8.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO70389.1 - 0.088 11.3 5.0 0.2 10.1 3.5 1.6 1 1 0 1 1 1 0 Sugar (and other) transporter DUF1218 PF06749.7 AEO70389.1 - 5.6 7.4 11.0 2.7 8.5 0.8 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1218) Hist_deacetyl PF00850.14 AEO70390.1 - 1.4e-79 267.6 0.2 2e-79 267.1 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain ING PF12998.2 AEO70391.1 - 1.5e-23 83.0 5.9 2.3e-23 82.4 4.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 AEO70391.1 - 1.2e-07 31.2 9.3 2e-07 30.6 6.4 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 AEO70391.1 - 0.033 14.3 0.1 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain UDPGP PF01704.13 AEO70392.1 - 2.9e-185 615.7 0.1 3.4e-185 615.5 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Phage_prot_Gp6 PF05133.9 AEO70392.1 - 0.031 12.8 0.3 0.051 12.1 0.2 1.2 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like SSDP PF04503.8 AEO70393.1 - 0.14 11.9 0.2 0.15 11.8 0.2 1.2 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP DUF3605 PF12239.3 AEO70394.1 - 5.3e-57 192.0 0.5 6.5e-57 191.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) PLRV_ORF5 PF01690.12 AEO70396.1 - 5.2 6.1 15.3 7.8 5.5 10.6 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein HAUS-augmin3 PF14932.1 AEO70397.1 - 0.0021 17.2 12.9 0.043 12.9 8.9 2.2 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 3 Spc7 PF08317.6 AEO70397.1 - 0.0084 14.8 6.3 0.017 13.7 4.3 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein TACC PF05010.9 AEO70397.1 - 0.019 14.7 12.2 0.035 13.8 8.4 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) NEMO PF11577.3 AEO70397.1 - 0.055 13.2 4.9 0.95 9.2 0.3 2.7 1 1 1 2 2 2 0 NF-kappa-B essential modulator NEMO AAA_13 PF13166.1 AEO70397.1 - 0.14 10.6 9.2 0.19 10.1 6.3 1.1 1 0 0 1 1 1 0 AAA domain DUF812 PF05667.6 AEO70397.1 - 0.16 10.4 16.1 0.23 9.9 10.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF4407 PF14362.1 AEO70397.1 - 0.18 10.6 12.2 0.34 9.8 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gp58 PF07902.6 AEO70397.1 - 0.21 9.7 1.7 0.3 9.2 1.2 1.2 1 0 0 1 1 1 0 gp58-like protein XLF PF09302.6 AEO70397.1 - 0.36 10.5 2.9 0.3 10.8 0.3 2.0 2 0 0 2 2 2 0 XLF (XRCC4-like factor) Phage_GP20 PF06810.6 AEO70397.1 - 0.83 9.0 6.7 2.1 7.7 0.4 2.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 ATG16 PF08614.6 AEO70397.1 - 0.91 9.3 21.3 0.079 12.7 5.6 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GED PF02212.13 AEO70397.1 - 1.7 8.6 5.3 25 4.8 0.7 2.8 1 1 1 2 2 2 0 Dynamin GTPase effector domain Spc24 PF08286.6 AEO70397.1 - 1.8 8.3 8.0 2 8.1 0.1 2.7 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 TBPIP PF07106.8 AEO70397.1 - 4.7 6.7 10.1 15 5.0 3.2 3.1 2 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 AEO70397.1 - 9.3 5.8 19.9 2.8 7.5 2.1 4.0 3 1 1 4 4 4 0 Septum formation initiator Telomerase_RBD PF12009.3 AEO70398.1 - 1.6e-14 53.9 0.1 3.2e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RhoGEF PF00621.15 AEO70399.1 - 2.9e-34 118.5 0.1 6.3e-34 117.4 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 AEO70399.1 - 4.5e-09 36.1 6.0 8.5e-09 35.2 3.0 2.2 1 1 1 2 2 2 1 BAR domain DUF896 PF05979.7 AEO70399.1 - 0.035 13.7 0.3 0.12 11.9 0.2 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) Velvet PF11754.3 AEO70400.1 - 4.5e-49 166.8 0.0 6.5e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Velvet factor DUF3602 PF12223.3 AEO70401.1 - 8.5e-14 51.7 3.5 8.5e-09 35.6 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) Acetyltransf_1 PF00583.19 AEO70402.1 - 0.00021 21.2 0.3 0.0011 18.9 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family FR47 PF08445.5 AEO70402.1 - 0.05 13.3 0.1 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_10 PF13673.1 AEO70402.1 - 0.055 13.5 0.1 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain URO-D PF01208.12 AEO70403.1 - 8.4e-122 406.3 0.0 9.5e-122 406.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Zn_clus PF00172.13 AEO70405.1 - 1e-07 31.6 10.0 2e-07 30.7 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MBOAT_2 PF13813.1 AEO70406.1 - 1.1e-15 57.3 7.1 2.3e-15 56.3 0.8 3.6 4 0 0 4 4 4 1 Membrane bound O-acyl transferase family MOSC_N PF03476.11 AEO70407.1 - 1.3e-23 82.9 0.0 3.1e-23 81.7 0.0 1.7 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.14 AEO70407.1 - 2.5e-19 69.2 0.0 7e-19 67.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V MOSC PF03473.12 AEO70407.1 - 4.4e-19 68.2 0.0 8.7e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 MOSC domain AAA_22 PF13401.1 AEO70408.1 - 2.4e-12 47.1 0.0 6.1e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO70408.1 - 1.5e-11 44.6 2.4 1.2e-10 41.6 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 AEO70408.1 - 1.5e-08 34.9 0.0 3.3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.6 AEO70408.1 - 0.00028 20.5 0.0 0.00086 18.9 0.0 1.8 1 0 0 1 1 1 1 CDC6, C terminal NACHT PF05729.7 AEO70408.1 - 0.00034 20.3 0.0 0.00079 19.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 AEO70408.1 - 0.00088 18.2 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_5 PF07728.9 AEO70408.1 - 0.0045 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 AEO70408.1 - 0.019 14.7 5.9 0.056 13.2 0.0 4.1 4 1 0 4 4 4 0 Part of AAA domain Arch_ATPase PF01637.13 AEO70408.1 - 0.027 14.1 0.0 0.055 13.1 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 AEO70408.1 - 0.041 14.0 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Miro PF08477.8 AEO70408.1 - 0.099 13.1 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein DUF815 PF05673.8 AEO70408.1 - 0.11 11.4 0.0 0.26 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Aldedh PF00171.17 AEO70409.1 - 3.2e-135 451.0 0.5 3.7e-135 450.8 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Calreticulin PF00262.13 AEO70410.1 - 5e-163 541.9 20.9 6.5e-163 541.6 14.5 1.1 1 0 0 1 1 1 1 Calreticulin family GvpK PF05121.7 AEO70410.1 - 0.21 11.4 0.1 0.4 10.5 0.1 1.4 1 0 0 1 1 1 0 Gas vesicle protein K Aldolase_II PF00596.16 AEO70411.1 - 1.3e-40 138.9 0.0 1.7e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Pollen_allerg_2 PF01620.11 AEO70412.1 - 0.044 14.0 8.1 0.075 13.3 5.6 1.3 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) TIL PF01826.12 AEO70412.1 - 9.7 6.3 10.7 3.3e+02 1.4 7.4 2.3 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Sld5 PF05916.6 AEO70413.1 - 5.1e-08 33.1 0.2 9.4e-08 32.3 0.2 1.5 1 0 0 1 1 1 1 GINS complex protein Arrestin_N PF00339.24 AEO70414.1 - 1.1e-17 64.1 0.0 2.3e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain MFS_1 PF07690.11 AEO70416.1 - 1.6e-47 161.9 50.5 2.3e-45 154.8 34.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO70416.1 - 2.6e-16 59.2 0.0 2.6e-16 59.2 0.0 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 AEO70416.1 - 3.4e-16 58.5 22.3 3.5e-16 58.5 13.9 1.9 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 AEO70416.1 - 0.006 14.7 0.7 0.006 14.7 0.5 2.5 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family F-box-like PF12937.2 AEO70417.1 - 7.4e-07 28.7 2.0 3e-06 26.8 0.6 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 AEO70417.1 - 5.9e-06 25.7 1.6 1.6e-05 24.4 1.1 1.8 1 0 0 1 1 1 1 F-box domain HET PF06985.6 AEO70418.1 - 2e-21 76.6 5.8 7.6e-18 65.0 0.5 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 AEO70418.1 - 2.2e-18 66.3 0.0 8.6e-10 38.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AEO70418.1 - 5.9e-17 60.5 0.1 1.1e-06 28.1 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 AEO70418.1 - 2.9e-16 59.4 0.1 8e-07 29.4 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO70418.1 - 9.6e-11 40.8 0.0 2.9e-05 23.8 0.0 3.4 3 0 0 3 3 2 2 Ankyrin repeat Ank_5 PF13857.1 AEO70418.1 - 1.1e-07 31.8 0.0 0.00011 22.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) CALCOCO1 PF07888.6 AEO70418.1 - 0.032 12.5 4.3 0.048 11.9 3.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like LEA_1 PF03760.10 AEO70418.1 - 0.27 11.4 2.5 0.65 10.1 1.7 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant (LEA) group 1 Atg14 PF10186.4 AEO70418.1 - 0.53 9.1 4.6 0.83 8.5 3.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 AEO70418.1 - 1.1 8.7 6.5 1.9 8.0 4.5 1.3 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 AEO70418.1 - 1.6 8.2 5.4 3.4 7.2 3.8 1.4 1 0 0 1 1 1 0 Septum formation initiator FAD_binding_3 PF01494.14 AEO70419.1 - 1.5e-53 182.1 0.0 1.9e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 AEO70419.1 - 4.1e-32 111.1 0.0 7.2e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Indigoidine_A PF04227.7 AEO70420.1 - 4.3e-75 252.6 0.1 8.1e-75 251.7 0.0 1.5 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 AEO70420.1 - 8.2e-23 80.9 0.0 8e-21 74.4 0.0 2.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Ins_P5_2-kin PF06090.7 AEO70420.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase WD40 PF00400.27 AEO70423.1 - 2.4e-10 39.8 2.4 0.15 11.9 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF2583 PF10762.4 AEO70423.1 - 0.0071 16.4 0.9 0.015 15.4 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2583) Sec20 PF03908.8 AEO70426.1 - 2e-15 56.2 0.2 5.3e-15 54.8 0.0 1.8 2 0 0 2 2 2 1 Sec20 MRP_L53 PF10780.4 AEO70427.1 - 3.3e-22 78.2 0.1 5.9e-22 77.3 0.1 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Pyrophosphatase PF00719.14 AEO70428.1 - 4.3e-52 175.6 0.1 5.4e-52 175.3 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Membr_traf_MHD PF10540.4 AEO70429.1 - 6.4e-23 81.0 0.2 1.6e-22 79.8 0.2 1.7 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 AEO70429.1 - 6.2e-18 64.4 0.0 1.5e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain TPR_12 PF13424.1 AEO70430.1 - 1.1e-05 25.2 0.1 4.7e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 AEO70430.1 - 0.00017 21.4 3.1 0.035 14.0 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 AEO70430.1 - 0.00022 21.5 0.1 0.087 13.1 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 AEO70430.1 - 0.0054 17.0 8.7 0.77 10.3 2.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 AEO70430.1 - 0.01 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 AEO70430.1 - 0.048 14.3 2.9 0.44 11.2 1.2 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 AEO70430.1 - 0.095 12.6 0.1 20 5.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PSK_trans_fac PF07704.6 AEO70430.1 - 0.87 10.3 4.4 1.1 9.9 1.4 2.4 2 1 0 2 2 2 0 Rv0623-like transcription factor TPR_14 PF13428.1 AEO70430.1 - 9 7.2 8.3 22 6.0 0.6 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat ArfGap PF01412.13 AEO70432.1 - 5.7e-33 113.1 1.7 8.9e-33 112.5 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 AEO70432.1 - 9.3e-14 51.5 0.1 2.5e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF4200 PF13863.1 AEO70432.1 - 0.011 15.6 3.0 0.011 15.6 2.1 3.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) EMP24_GP25L PF01105.19 AEO70432.1 - 0.069 12.8 4.3 3.9 7.1 1.2 2.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD PilJ PF13675.1 AEO70432.1 - 0.14 12.5 7.7 0.047 14.0 0.5 2.9 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term PH_9 PF15410.1 AEO70432.1 - 0.35 11.0 4.1 0.31 11.2 0.3 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain Syntaxin_2 PF14523.1 AEO70432.1 - 2.3 8.2 8.8 2.5 8.2 0.4 3.1 2 1 0 2 2 2 0 Syntaxin-like protein FAD_binding_3 PF01494.14 AEO70433.1 - 5.3e-13 48.7 0.7 1.2e-05 24.6 0.0 2.4 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 AEO70433.1 - 4.6e-07 29.0 0.1 0.014 14.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO70433.1 - 0.0019 17.1 0.3 0.0076 15.1 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 AEO70433.1 - 0.0073 16.6 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 AEO70434.1 - 2.5e-73 246.4 0.0 3.4e-73 245.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO70434.1 - 2.9e-38 131.4 0.0 4.5e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 AEO70434.1 - 2.4e-16 59.6 0.2 5.5e-16 58.4 0.1 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 AEO70434.1 - 1e-08 34.4 0.0 5.4e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AEO70434.1 - 0.00013 21.0 0.0 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 AEO70434.1 - 0.017 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PCI PF01399.22 AEO70435.1 - 1.1e-15 57.8 0.2 3.7e-14 52.9 0.1 2.9 3 0 0 3 3 3 1 PCI domain BCAS2 PF05700.6 AEO70435.1 - 0.027 13.9 0.5 0.049 13.0 0.3 1.4 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Nucleopor_Nup85 PF07575.8 AEO70435.1 - 0.03 12.5 0.0 0.046 11.9 0.0 1.3 1 0 0 1 1 1 0 Nup85 Nucleoporin ADK PF00406.17 AEO70436.1 - 2.7e-44 150.7 0.0 3.9e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 AEO70436.1 - 1.6e-06 28.8 0.0 2.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO70436.1 - 2.3e-06 27.9 0.0 3.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AEO70436.1 - 1.1e-05 25.3 0.9 6.1e-05 22.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 AEO70436.1 - 0.0003 20.2 0.0 0.017 14.5 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase PAS_7 PF12860.2 AEO70436.1 - 0.14 12.2 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 PAS fold DUF3329 PF11808.3 AEO70437.1 - 0.13 12.3 0.4 0.72 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) DUF202 PF02656.10 AEO70437.1 - 0.17 12.1 6.0 0.17 12.1 0.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF3446 PF11928.3 AEO70437.1 - 7.1 6.8 18.2 4.3 7.6 4.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) GTP_EFTU PF00009.22 AEO70439.1 - 2.7e-39 134.5 0.0 4.7e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 AEO70439.1 - 1.8e-37 127.2 0.4 3.7e-37 126.2 0.3 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 AEO70439.1 - 1.5e-09 37.7 0.1 3.4e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AEO70439.1 - 0.0089 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Nsp1_C PF05064.8 AEO70441.1 - 4.8e-42 142.2 0.4 1.1e-41 141.0 0.2 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 AEO70441.1 - 3e-13 49.9 218.6 0.00021 21.4 28.2 6.4 1 1 2 3 3 1 1 Nucleoporin FG repeat region Myosin_tail_1 PF01576.14 AEO70441.1 - 0.0044 14.8 6.0 0.41 8.2 2.5 1.9 2 0 0 2 2 2 2 Myosin tail AAA_13 PF13166.1 AEO70441.1 - 0.018 13.5 1.3 0.034 12.6 0.2 1.7 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 AEO70441.1 - 0.029 13.9 0.3 0.064 12.8 0.2 1.6 1 1 0 1 1 1 0 IncA protein Spc7 PF08317.6 AEO70441.1 - 0.13 10.8 6.5 1.7 7.2 0.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 AEO70441.1 - 0.17 11.7 0.9 1.6 8.5 0.1 2.2 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_porin PF12795.2 AEO70441.1 - 0.22 10.8 10.5 2.6 7.3 2.7 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain EzrA PF06160.7 AEO70441.1 - 0.35 8.9 5.2 5.2 5.1 1.4 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF972 PF06156.8 AEO70441.1 - 0.35 11.2 1.4 2.5 8.5 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) ApoLp-III PF07464.6 AEO70441.1 - 1.4 8.9 6.4 3.3 7.7 3.3 2.2 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Fib_alpha PF08702.5 AEO70441.1 - 2 8.5 3.3 21 5.1 0.2 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.1 AEO70441.1 - 4 7.3 9.6 0.77 9.7 3.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Laminin_II PF06009.7 AEO70441.1 - 7.8 6.2 6.4 4.6 6.9 0.5 2.7 2 1 0 2 2 2 0 Laminin Domain II IATP PF04568.7 AEO70442.1 - 3.1e-22 78.4 0.8 3.7e-22 78.2 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP MutS_III PF05192.13 AEO70442.1 - 0.034 13.9 0.1 0.039 13.7 0.0 1.1 1 0 0 1 1 1 0 MutS domain III DUF489 PF04356.7 AEO70442.1 - 0.038 13.5 0.5 0.048 13.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Atg14 PF10186.4 AEO70442.1 - 0.049 12.5 0.5 0.048 12.5 0.3 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 AEO70442.1 - 0.052 13.1 0.6 0.049 13.2 0.4 1.1 1 0 0 1 1 1 0 IncA protein DUF1003 PF06210.6 AEO70442.1 - 0.056 13.3 2.4 0.076 12.9 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) NPV_P10 PF05531.7 AEO70442.1 - 0.061 13.5 0.7 0.094 12.9 0.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1352 PF07086.7 AEO70442.1 - 0.071 12.7 0.1 0.086 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1352) DivIC PF04977.10 AEO70442.1 - 0.11 11.9 3.3 0.17 11.3 2.3 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.10 AEO70442.1 - 7.3 6.5 11.3 0.63 9.9 4.7 1.5 2 0 0 2 2 2 0 Basic region leucine zipper adh_short_C2 PF13561.1 AEO70443.1 - 0.045 13.5 0.0 0.046 13.4 0.0 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 14-3-3 PF00244.15 AEO70444.1 - 1.5e-116 387.4 1.7 1.8e-116 387.2 1.2 1.0 1 0 0 1 1 1 1 14-3-3 protein zf-CSL PF05207.8 AEO70445.1 - 5.4e-14 51.4 0.3 1.1e-13 50.3 0.0 1.6 2 0 0 2 2 2 1 CSL zinc finger DnaJ PF00226.26 AEO70445.1 - 1.2e-09 37.7 2.6 3e-09 36.4 1.8 1.7 1 1 0 1 1 1 1 DnaJ domain DEAD PF00270.24 AEO70446.1 - 2.1e-41 141.2 0.0 2.2e-40 137.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO70446.1 - 1.2e-25 89.1 0.0 2.7e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3334 PF11813.3 AEO70446.1 - 0.002 17.6 0.4 0.033 13.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3334) DUF2986 PF11661.3 AEO70446.1 - 0.017 15.4 3.1 0.017 15.4 2.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2986) ResIII PF04851.10 AEO70446.1 - 0.042 13.6 0.0 0.12 12.1 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Collagen PF01391.13 AEO70446.1 - 1.5 8.3 13.4 2 8.0 6.3 2.8 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) Mito_carr PF00153.22 AEO70447.1 - 2.9e-61 203.1 0.1 2.4e-21 75.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein KfrA_N PF11740.3 AEO70447.1 - 0.056 13.8 0.2 0.056 13.8 0.1 1.8 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term TspO_MBR PF03073.10 AEO70448.1 - 2.3e-36 124.5 8.6 3.4e-36 123.9 6.0 1.2 1 0 0 1 1 1 1 TspO/MBR family DUF3546 PF12066.3 AEO70449.1 - 1.5e-27 95.8 1.1 1.5e-27 95.8 0.8 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 AEO70449.1 - 4.8e-23 80.4 0.0 1.3e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 AEO70449.1 - 9.4e-13 48.8 3.3 2.7e-12 47.3 2.3 1.8 1 0 0 1 1 1 1 Arsenite-resistance protein 2 NBP1 PF08537.5 AEO70449.1 - 4.3 6.4 13.0 4.3 6.4 0.7 2.2 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 Cpn60_TCP1 PF00118.19 AEO70451.1 - 1.7e-137 459.0 13.7 2.1e-137 458.6 9.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 AEO70451.1 - 0.027 13.9 0.0 0.078 12.4 0.0 1.7 1 0 0 1 1 1 0 Phage Tail Protein X AAA PF00004.24 AEO70452.1 - 9.8e-41 139.0 0.0 1.7e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO70452.1 - 4.7e-06 26.7 0.0 0.00059 19.9 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 AEO70452.1 - 2.8e-05 23.8 0.1 0.00024 20.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AEO70452.1 - 0.00024 21.0 0.0 0.00071 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 AEO70452.1 - 0.00024 21.1 0.1 0.001 19.0 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain DUF815 PF05673.8 AEO70452.1 - 0.0022 16.9 0.0 0.0039 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 AEO70452.1 - 0.0044 17.8 0.1 0.013 16.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AEO70452.1 - 0.0085 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AEO70452.1 - 0.0097 15.6 0.2 0.022 14.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 AEO70452.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 AEO70452.1 - 0.025 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 AEO70452.1 - 0.028 14.0 0.0 0.6 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 AEO70452.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AEO70452.1 - 0.043 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 AEO70452.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 AEO70452.1 - 0.068 13.2 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 AEO70452.1 - 0.073 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 AEO70452.1 - 0.093 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 AEO70452.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 AEO70452.1 - 0.13 11.9 0.3 11 5.6 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase Mg_chelatase PF01078.16 AEO70452.1 - 0.14 11.2 0.0 0.33 10.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RRM_1 PF00076.17 AEO70454.1 - 5.7e-19 67.5 0.3 1.9e-18 65.8 0.1 1.8 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO70454.1 - 3.5e-13 49.3 0.0 5.5e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO70454.1 - 1.8e-09 37.3 0.1 2.8e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3661 PF12400.3 AEO70455.1 - 2.6e-43 147.2 4.8 3.7e-43 146.6 3.3 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein Tyrosinase PF00264.15 AEO70456.1 - 2e-59 201.4 1.5 3.9e-59 200.5 1.1 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase RNA_pol_Rpb2_6 PF00562.23 AEO70457.1 - 6.1e-116 387.3 0.0 7.8e-116 386.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AEO70457.1 - 4e-29 101.0 0.0 5.9e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 AEO70457.1 - 3.6e-25 88.4 0.0 7.8e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 AEO70457.1 - 4.6e-25 87.1 0.0 9.7e-25 86.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 AEO70457.1 - 6e-24 83.7 0.0 1.5e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 AEO70457.1 - 6.2e-15 55.2 0.0 2.9e-14 53.0 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 AEO70457.1 - 4.4e-05 23.3 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Rpr2 PF04032.11 AEO70457.1 - 0.14 12.0 0.3 0.28 11.0 0.2 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Arf PF00025.16 AEO70458.1 - 1.4e-43 148.1 0.0 1.7e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 AEO70458.1 - 4.6e-19 68.3 0.0 5.2e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO70458.1 - 3e-09 37.4 0.0 6.6e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein G-alpha PF00503.15 AEO70458.1 - 1.3e-07 30.7 0.0 2.8e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.7 AEO70458.1 - 7.6e-07 28.5 0.0 8.9e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 AEO70458.1 - 1.8e-05 24.0 0.0 2.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AEO70458.1 - 2.1e-05 24.4 0.0 4e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AEO70458.1 - 8.2e-05 22.1 0.0 0.0022 17.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 AEO70458.1 - 0.0024 17.1 0.4 0.0098 15.1 0.3 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AEO70458.1 - 0.024 14.4 0.1 0.14 11.9 0.1 1.9 1 1 1 2 2 2 0 Dynamin family PduV-EutP PF10662.4 AEO70458.1 - 0.04 13.3 0.0 0.28 10.6 0.0 2.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_S9 PF00380.14 AEO70459.1 - 4e-35 120.6 0.2 4.6e-35 120.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 RCR PF12273.3 AEO70460.1 - 4.7e-23 82.1 5.5 6.2e-23 81.7 3.8 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red GP41 PF00517.12 AEO70460.1 - 0.0022 17.5 0.0 0.0027 17.3 0.0 1.1 1 0 0 1 1 1 1 Retroviral envelope protein WBP-1 PF11669.3 AEO70460.1 - 0.022 14.8 1.4 0.022 14.8 1.0 1.8 2 1 0 2 2 2 0 WW domain-binding protein 1 DUF4131 PF13567.1 AEO70460.1 - 0.029 13.8 1.2 0.039 13.3 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) BatD PF13584.1 AEO70460.1 - 0.19 10.2 0.3 0.25 9.9 0.2 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF2140 PF09911.4 AEO70460.1 - 0.2 10.8 0.2 0.25 10.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF4381 PF14316.1 AEO70460.1 - 0.45 10.6 3.9 0.73 9.9 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Corona_S2 PF01601.11 AEO70461.1 - 1.1 7.2 20.8 1.5 6.7 14.4 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Methyltransf_23 PF13489.1 AEO70463.1 - 1.8e-20 73.2 0.0 2.9e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO70463.1 - 5.2e-10 39.6 0.0 1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO70463.1 - 9.9e-08 32.5 0.0 1.1e-06 29.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO70463.1 - 2.9e-06 27.6 0.0 1.3e-05 25.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO70463.1 - 6.4e-06 25.8 0.0 0.0041 16.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.13 AEO70463.1 - 0.00017 20.8 0.0 0.0012 18.0 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 AEO70463.1 - 0.00066 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 AEO70463.1 - 0.0038 17.2 0.7 0.037 14.0 0.5 2.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 AEO70463.1 - 0.0072 16.6 0.0 0.025 14.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AEO70463.1 - 0.0077 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 AEO70463.1 - 0.01 15.8 0.0 0.082 12.9 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 AEO70463.1 - 0.042 12.8 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 AEO70463.1 - 0.053 12.8 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DUF938 PF06080.7 AEO70463.1 - 0.17 11.4 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) AmoC PF04896.7 AEO70465.1 - 0.06 12.3 0.0 9.5 5.1 0.0 2.1 2 0 0 2 2 2 0 Ammonia monooxygenase/methane monooxygenase, subunit C Ppx-GppA PF02541.11 AEO70467.1 - 3e-29 102.0 0.0 3e-28 98.8 0.0 2.0 1 1 0 1 1 1 1 Ppx/GppA phosphatase family Per1 PF04080.8 AEO70469.1 - 2.6e-100 335.2 5.1 3.3e-100 334.9 3.5 1.1 1 0 0 1 1 1 1 Per1-like Acetyltransf_3 PF13302.1 AEO70470.1 - 1.3e-29 103.1 0.0 1.5e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AEO70470.1 - 3.9e-05 23.6 0.0 6.1e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AEO70470.1 - 0.00011 22.0 0.0 0.00016 21.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO70470.1 - 0.0049 16.8 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family COPIIcoated_ERV PF07970.7 AEO70471.1 - 1.9e-72 243.5 0.0 9.1e-71 238.0 0.0 2.2 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 AEO70471.1 - 9e-36 121.7 0.1 2.5e-35 120.3 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sel1 PF08238.7 AEO70472.1 - 2.2e-15 56.7 10.7 0.00026 21.5 0.0 4.4 4 0 0 4 4 4 3 Sel1 repeat Proteasome PF00227.21 AEO70473.1 - 5.1e-46 156.3 0.1 6.5e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 AEO70473.1 - 7.4e-13 47.5 0.3 1.5e-12 46.5 0.2 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal DUF342 PF03961.8 AEO70474.1 - 0.036 12.4 0.3 0.057 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3708 PF12501.3 AEO70474.1 - 0.28 11.0 2.7 0.69 9.7 1.8 1.7 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter AAA_13 PF13166.1 AEO70474.1 - 0.91 7.9 1.2 1.3 7.3 0.8 1.1 1 0 0 1 1 1 0 AAA domain Nucleoporin_FG PF13634.1 AEO70474.1 - 3.6 7.8 104.6 6.8 6.9 19.2 5.6 2 1 1 3 3 3 0 Nucleoporin FG repeat region ER_lumen_recept PF00810.13 AEO70475.1 - 1.5e-36 126.0 12.8 2.2e-36 125.5 8.9 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 AEO70475.1 - 0.061 12.8 0.1 0.061 12.8 0.1 3.0 3 0 0 3 3 3 0 PQ loop repeat LicD PF04991.8 AEO70476.1 - 9.9e-19 68.2 0.1 1.1e-16 61.5 0.1 2.0 1 1 0 1 1 1 1 LicD family Cmc1 PF08583.5 AEO70477.1 - 0.012 15.3 1.1 0.054 13.2 0.8 2.2 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pex14_N PF04695.8 AEO70477.1 - 0.13 12.3 7.8 0.26 11.3 5.4 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_hydro_18 PF00704.23 AEO70479.1 - 1.3e-97 327.3 0.5 1.5e-97 327.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Acyl_transf_3 PF01757.17 AEO70480.1 - 1.3 7.7 11.1 1.6 7.4 7.7 1.1 1 0 0 1 1 1 0 Acyltransferase family LRR_6 PF13516.1 AEO70481.1 - 1e-12 46.6 9.1 0.0031 17.4 0.0 7.1 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.2 AEO70481.1 - 3.5e-10 39.2 7.0 0.0023 17.5 0.0 5.3 4 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AEO70481.1 - 5e-06 25.8 6.6 5.1 7.5 0.0 6.0 6 1 1 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.1 AEO70481.1 - 0.00012 21.7 10.2 0.49 10.1 0.0 4.3 3 2 0 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 AEO70481.1 - 0.0022 17.8 5.8 21 5.8 0.0 5.5 5 0 0 5 5 5 1 Leucine rich repeat LETM1 PF07766.8 AEO70481.1 - 0.046 12.7 0.0 0.046 12.7 0.0 2.3 3 0 0 3 3 3 0 LETM1-like protein LKAAEAR PF15478.1 AEO70481.1 - 8.4 6.6 7.7 13 6.0 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function with LKAAEAR motif zf-H2C2_2 PF13465.1 AEO70482.1 - 3.5e-06 27.0 1.0 3.5e-06 27.0 0.7 3.8 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO70482.1 - 2.3e-05 24.3 4.2 0.00061 19.9 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO70482.1 - 0.00019 21.6 0.3 0.00019 21.6 0.2 3.8 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 AEO70482.1 - 4.6 7.5 7.8 4.4 7.5 0.3 3.3 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Fe_hyd_lg_C PF02906.9 AEO70484.1 - 7.5e-61 205.8 0.0 2.3e-60 204.3 0.0 1.7 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SUZ PF12752.2 AEO70485.1 - 2.1e-07 31.3 3.8 2.1e-07 31.3 2.7 2.8 2 1 0 2 2 2 1 SUZ domain Utp21 PF04192.7 AEO70485.1 - 0.0099 15.0 3.2 0.016 14.3 2.2 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain DUF1754 PF08555.5 AEO70485.1 - 0.098 13.2 9.0 3.8 8.1 2.6 2.9 3 0 0 3 3 3 0 Eukaryotic family of unknown function (DUF1754) ARGLU PF15346.1 AEO70485.1 - 0.19 11.4 14.4 0.025 14.3 3.9 2.1 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Cmyb_C PF09316.5 AEO70485.1 - 6.7 6.3 9.9 0.38 10.4 2.6 1.9 1 1 1 2 2 2 0 C-myb, C-terminal Pkinase PF00069.20 AEO70487.1 - 4.1e-71 239.1 0.0 5.5e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO70487.1 - 5.2e-31 107.6 0.0 7.3e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 AEO70487.1 - 2.2e-14 53.6 1.4 8e-14 51.8 1.0 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 AEO70487.1 - 3.4e-09 36.0 0.0 6.4e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AEO70487.1 - 0.024 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 AEO70487.1 - 0.052 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 AEO70487.1 - 0.088 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ATP_sub_h PF10775.4 AEO70488.1 - 4e-25 87.3 1.0 6.5e-25 86.6 0.7 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h DUF2427 PF10348.4 AEO70489.1 - 5.2e-06 25.9 0.8 5.2e-06 25.9 0.6 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF2427) 7TMR-DISM_7TM PF07695.6 AEO70489.1 - 0.12 12.0 6.1 0.064 12.9 2.3 2.0 1 1 0 1 1 1 0 7TM diverse intracellular signalling EI24 PF07264.6 AEO70489.1 - 0.76 9.1 9.4 0.89 8.9 0.5 2.2 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Tetraspannin PF00335.15 AEO70489.1 - 1.1 8.4 7.6 1.3 8.1 4.1 2.1 2 1 0 2 2 2 0 Tetraspanin family DUF373 PF04123.8 AEO70489.1 - 6.8 5.6 6.9 25 3.7 4.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Pkinase PF00069.20 AEO70490.1 - 1.8e-66 223.9 0.0 2.3e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO70490.1 - 2.3e-29 102.2 0.0 3.1e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 AEO70490.1 - 0.0078 16.7 0.3 0.021 15.3 0.2 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 AEO70490.1 - 0.012 14.6 0.1 0.028 13.3 0.0 1.5 1 1 1 2 2 2 0 Kinase-like APH PF01636.18 AEO70490.1 - 0.03 14.0 0.7 0.65 9.6 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF515 PF04415.7 AEO70490.1 - 1.1 7.3 3.0 1.7 6.8 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) WD40 PF00400.27 AEO70491.1 - 1.3e-50 167.5 21.5 5.1e-10 38.8 0.8 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 AEO70491.1 - 7.5e-16 57.1 3.3 1.3e-15 56.3 2.3 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 AEO70491.1 - 0.016 14.8 0.0 2.2 7.9 0.0 3.5 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 AEO70491.1 - 0.027 13.5 0.1 1.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 AEO70491.1 - 0.13 10.9 0.7 7.7 5.1 0.1 2.2 1 1 1 2 2 2 0 Nup133 N terminal like Ribosomal_60s PF00428.14 AEO70491.1 - 1.1 9.6 14.3 4.3 7.8 9.9 2.0 1 1 0 1 1 1 0 60s Acidic ribosomal protein Cyclin_N PF00134.18 AEO70492.1 - 4.3e-10 39.2 0.0 8.9e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Dus PF01207.12 AEO70493.1 - 6.7e-26 90.8 0.0 1e-22 80.4 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) AIRC PF00731.15 AEO70494.1 - 1.6e-58 196.2 0.3 3.3e-58 195.2 0.2 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 AEO70494.1 - 7.9e-49 165.3 0.0 1.5e-48 164.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 AEO70494.1 - 9.2e-13 48.3 0.2 2.5e-12 46.9 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AEO70494.1 - 1.7e-05 24.2 0.0 4.6e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus XdhC_C PF13478.1 AEO70494.1 - 6.5e-05 23.2 0.1 0.1 12.9 0.0 2.8 3 0 0 3 3 3 2 XdhC Rossmann domain DUF1180 PF06679.7 AEO70494.1 - 0.0003 20.7 0.9 0.00077 19.3 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) CPSase_L_D2 PF02786.12 AEO70494.1 - 0.0042 16.3 0.1 0.26 10.5 0.0 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PrpR_N PF06506.6 AEO70494.1 - 0.0043 16.4 0.1 0.034 13.5 0.0 2.3 2 0 0 2 2 2 1 Propionate catabolism activator 2-Hacid_dh_C PF02826.14 AEO70494.1 - 0.011 14.9 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATPgrasp_Ter PF15632.1 AEO70494.1 - 0.11 11.1 0.0 0.63 8.7 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon Fer2_3 PF13085.1 AEO70496.1 - 2.5e-33 114.1 0.0 4.1e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 AEO70496.1 - 2.9e-09 37.1 6.1 2.9e-09 37.1 4.2 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 AEO70496.1 - 3.7e-09 36.4 4.4 3.7e-09 36.4 3.1 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 AEO70496.1 - 0.00017 21.3 4.1 0.00017 21.3 2.9 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 AEO70496.1 - 0.00019 21.5 4.2 0.032 14.4 0.5 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 AEO70496.1 - 0.00023 21.5 1.4 0.00023 21.5 1.0 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.22 AEO70496.1 - 0.0049 16.5 0.4 0.0049 16.5 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DNA_pol3_tau_4 PF12168.3 AEO70496.1 - 0.33 11.3 3.8 0.46 10.9 0.6 2.2 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_7 PF12838.2 AEO70496.1 - 1.6 9.1 14.5 0.038 14.3 4.3 2.5 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 AEO70496.1 - 2.6 8.6 6.3 1 9.9 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain GRP PF07172.6 AEO70497.1 - 0.015 15.7 5.3 0.015 15.7 3.7 2.8 3 0 0 3 3 3 0 Glycine rich protein family Mei5 PF10376.4 AEO70497.1 - 0.17 11.3 0.3 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 Double-strand recombination repair protein DUF605 PF04652.11 AEO70497.1 - 0.59 9.4 19.9 0.83 8.9 13.8 1.2 1 0 0 1 1 1 0 Vta1 like Sel1 PF08238.7 AEO70498.1 - 9.9e-43 143.6 52.6 9.3e-07 29.2 0.1 12.5 14 1 1 15 15 15 10 Sel1 repeat WD40 PF00400.27 AEO70499.1 - 1.3e-11 43.8 0.7 0.0017 18.1 0.0 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Thiolase_N PF00108.18 AEO70500.1 - 4.3e-93 311.0 0.4 4.3e-93 311.0 0.3 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AEO70500.1 - 1.3e-47 160.2 0.3 3.2e-47 158.9 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 AEO70500.1 - 8.9e-05 22.0 0.8 0.00022 20.8 0.6 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 AEO70500.1 - 0.075 12.6 3.9 0.58 9.8 0.1 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.22 AEO70501.1 - 2.6e-44 150.9 0.0 3.7e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 AEO70501.1 - 3.4e-28 97.6 0.0 9.4e-28 96.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 AEO70501.1 - 1.8e-18 66.2 0.0 6e-18 64.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AEO70501.1 - 6.3e-10 39.0 0.1 1.6e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 AEO70501.1 - 3.8e-06 26.6 0.0 8.5e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 AEO70501.1 - 5.2e-06 26.3 0.1 9.6e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AEO70501.1 - 0.00056 20.3 0.1 0.0015 18.9 0.1 1.8 1 0 0 1 1 1 1 Miro-like protein DUF59 PF01883.14 AEO70502.1 - 5.5e-05 23.0 0.1 0.00024 21.0 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function DUF59 Mmp37 PF09139.6 AEO70502.1 - 0.061 12.3 0.0 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial matrix Mmp37 Fungal_trans PF04082.13 AEO70504.1 - 8.6e-12 44.4 0.1 1.4e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO70504.1 - 1.1e-06 28.3 9.6 1.1e-06 28.3 6.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAH PF02671.16 AEO70506.1 - 3e-41 138.7 2.7 2e-17 62.5 0.6 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 AEO70506.1 - 2e-39 133.4 0.0 4.3e-39 132.3 0.0 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor HEPN PF05168.9 AEO70506.1 - 0.013 15.4 0.1 0.037 13.9 0.1 1.8 1 0 0 1 1 1 0 HEPN domain Fasciclin PF02469.17 AEO70506.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Fasciclin domain FAD_binding_2 PF00890.19 AEO70507.1 - 5.7e-85 285.6 1.2 7.2e-85 285.3 0.8 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 AEO70507.1 - 1.8e-21 75.7 0.3 1.8e-20 72.5 0.0 2.8 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 AEO70507.1 - 3.2e-12 46.0 1.9 1.6e-11 43.7 1.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 AEO70507.1 - 1.1e-10 41.1 0.4 4.4e-10 39.2 0.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO70507.1 - 3.6e-08 33.2 2.2 4.8e-07 29.7 0.3 3.0 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AEO70507.1 - 2e-07 31.1 0.0 1.9e-05 24.6 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO70507.1 - 6.8e-07 28.1 0.4 0.0047 15.4 0.0 3.3 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 AEO70507.1 - 4.5e-05 22.6 1.6 0.0069 15.5 0.4 2.6 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.17 AEO70507.1 - 0.00023 20.1 1.1 0.11 11.2 0.4 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 AEO70507.1 - 0.00074 18.7 0.2 0.14 11.1 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 AEO70507.1 - 0.0035 16.4 3.1 0.012 14.6 2.1 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 AEO70507.1 - 0.022 14.8 1.0 0.072 13.1 0.7 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO70507.1 - 0.22 11.9 2.2 1.6 9.1 0.3 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Nop14 PF04147.7 AEO70508.1 - 0.15 9.9 12.1 0.25 9.2 8.4 1.3 1 0 0 1 1 1 0 Nop14-like family PBP_sp32 PF07222.7 AEO70508.1 - 0.16 11.1 4.1 0.28 10.3 2.9 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pox_Ag35 PF03286.9 AEO70508.1 - 0.68 9.4 19.2 0.021 14.3 6.5 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF3246 PF11596.3 AEO70508.1 - 1.6 7.9 4.7 0.22 10.7 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) PBP1_TM PF14812.1 AEO70508.1 - 2.8 8.3 26.8 0.19 12.0 3.2 3.0 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC27 PF09507.5 AEO70508.1 - 2.8 7.0 25.2 0.31 10.2 7.2 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 PGA2 PF07543.7 AEO70508.1 - 5.1 6.8 14.9 2.3 7.9 8.1 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 Sugar_tr PF00083.19 AEO70509.1 - 1.8e-123 412.5 21.3 2.1e-123 412.2 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO70509.1 - 3.4e-21 75.3 38.5 8.2e-16 57.6 9.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha_L_fucos PF01120.12 AEO70509.1 - 0.24 10.2 0.5 0.38 9.6 0.3 1.2 1 0 0 1 1 1 0 Alpha-L-fucosidase Glyco_hydro_31 PF01055.21 AEO70510.1 - 2.2e-162 540.9 2.6 2.8e-162 540.5 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Rotavirus_VP7 PF05868.6 AEO70510.1 - 0.0011 18.2 0.1 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 Rotavirus major outer capsid protein VP7 DUF4448 PF14610.1 AEO70511.1 - 4e-36 124.2 0.0 5.8e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3304 PF11745.3 AEO70511.1 - 0.27 11.4 1.8 19 5.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3304) 2OG-FeII_Oxy PF03171.15 AEO70512.1 - 0.032 14.5 0.0 0.074 13.3 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FRG1 PF06229.7 AEO70513.1 - 1.5e-58 197.3 0.1 2.3e-58 196.8 0.0 1.3 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 AEO70513.1 - 0.013 15.5 0.0 0.042 13.9 0.0 1.9 2 0 0 2 2 2 0 Fascin domain Frataxin_Cyay PF01491.11 AEO70513.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Frataxin-like domain SRF-TF PF00319.13 AEO70514.1 - 4.1e-24 83.5 0.2 5.9e-24 83.0 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) VCBS PF13517.1 AEO70515.1 - 1e-23 83.4 32.4 1.9e-08 34.5 0.5 6.8 2 2 5 7 7 7 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.1 AEO70515.1 - 1e-16 61.5 0.1 2.8e-16 60.1 0.1 1.8 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO70515.1 - 2.7e-12 47.0 0.1 4.9e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FG-GAP PF01839.18 AEO70515.1 - 1.2e-08 34.3 32.4 0.0013 18.3 0.3 6.2 7 0 0 7 7 7 4 FG-GAP repeat TcdB_toxin_midN PF12256.3 AEO70515.1 - 2e-05 24.1 11.6 0.25 10.7 0.0 5.5 3 2 3 6 6 6 3 Insecticide toxin TcdB middle/N-terminal region DUF3591 PF12157.3 AEO70516.1 - 1.1e-185 617.3 0.0 1.1e-185 617.3 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 AEO70516.1 - 0.0053 16.3 1.9 0.013 15.1 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 AEO70516.1 - 0.015 15.1 0.9 0.026 14.4 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle D-ser_dehydrat PF14031.1 AEO70517.1 - 3.9e-24 84.6 0.0 7.8e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 AEO70517.1 - 3e-05 23.6 0.1 9.9e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain Actin PF00022.14 AEO70518.1 - 1.2e-137 458.5 0.0 1.3e-137 458.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AEO70518.1 - 0.032 12.8 0.0 3.5 6.1 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein PIG-P PF08510.7 AEO70519.1 - 8.8e-44 148.1 0.0 1.7e-43 147.2 0.0 1.5 1 0 0 1 1 1 1 PIG-P CDC45 PF02724.9 AEO70519.1 - 0.0069 14.4 0.7 0.0075 14.3 0.5 1.1 1 0 0 1 1 1 1 CDC45-like protein Pex14_N PF04695.8 AEO70519.1 - 0.19 11.7 1.0 5.6 7.0 0.7 2.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nop14 PF04147.7 AEO70519.1 - 0.41 8.5 7.1 0.53 8.1 4.9 1.0 1 0 0 1 1 1 0 Nop14-like family DPM2 PF07297.7 AEO70519.1 - 4.8 7.5 10.5 7.7 6.8 7.3 1.2 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Vps8 PF12816.2 AEO70520.1 - 1.3e-73 246.4 0.0 2.7e-73 245.3 0.0 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 AEO70520.1 - 1e-05 25.1 0.1 0.25 10.9 0.0 3.6 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 AEO70520.1 - 0.00045 19.9 0.1 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO70520.1 - 0.0018 18.2 0.0 0.0048 16.9 0.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO70520.1 - 0.023 14.4 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.2 AEO70520.1 - 0.082 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 AEO70520.1 - 0.088 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF3752 PF12572.3 AEO70521.1 - 8.9e-43 146.0 6.2 1.9e-42 144.9 4.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) zf-RING_2 PF13639.1 AEO70522.1 - 3.9e-14 52.2 6.8 6.2e-14 51.5 4.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AEO70522.1 - 1.5e-08 34.6 4.3 3e-08 33.6 3.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 AEO70522.1 - 3.3e-08 33.0 4.4 5.4e-08 32.3 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO70522.1 - 1.1e-06 28.2 4.1 1.7e-06 27.6 2.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO70522.1 - 1.4e-05 25.0 5.5 2.3e-05 24.3 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO70522.1 - 5.1e-05 22.8 2.4 7.8e-05 22.2 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AEO70522.1 - 0.00024 20.8 2.6 0.00052 19.7 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 AEO70522.1 - 0.01 15.4 6.8 0.017 14.6 4.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 AEO70522.1 - 0.02 14.6 0.4 0.063 13.0 0.1 2.0 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AEO70522.1 - 0.049 13.5 4.6 0.1 12.4 3.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.24 AEO70522.1 - 0.091 12.4 5.7 0.17 11.5 3.9 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 AEO70522.1 - 0.24 11.3 3.5 0.64 10.0 2.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 AEO70522.1 - 0.32 11.0 5.8 0.63 10.1 4.0 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 AEO70522.1 - 1 9.1 8.7 0.068 12.9 1.1 2.1 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 APH PF01636.18 AEO70523.1 - 1e-16 61.3 0.2 1.6e-12 47.6 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF1679 PF07914.6 AEO70523.1 - 0.00086 18.0 0.0 0.0011 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 AEO70523.1 - 0.0083 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 AEO70523.1 - 0.022 13.9 0.0 0.049 12.7 0.0 1.6 1 1 0 1 1 1 0 Protein kinase domain EcKinase PF02958.15 AEO70523.1 - 0.039 13.0 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Carbpep_Y_N PF05388.6 AEO70523.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide Peptidase_M16 PF00675.15 AEO70524.1 - 1.5e-57 193.5 0.5 3.8e-57 192.2 0.3 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 AEO70524.1 - 2.6e-39 134.7 0.0 3.2e-38 131.2 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain F-actin_cap_A PF01267.12 AEO70524.1 - 0.059 12.4 0.0 0.14 11.2 0.0 1.4 1 1 0 1 1 1 0 F-actin capping protein alpha subunit Raffinose_syn PF05691.7 AEO70525.1 - 9.1e-49 165.6 0.4 2.3e-44 151.1 0.2 3.0 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 AEO70525.1 - 9.2e-05 21.3 1.7 0.00021 20.1 1.2 1.4 2 0 0 2 2 2 1 Melibiase Glyco_hydro_31 PF01055.21 AEO70525.1 - 0.0001 21.3 0.1 0.00015 20.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF1713 PF08213.6 AEO70526.1 - 8.7e-12 44.4 22.3 1.6e-11 43.5 15.5 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) EF_assoc_1 PF08355.7 AEO70526.1 - 0.13 11.5 0.6 0.25 10.6 0.4 1.5 1 0 0 1 1 1 0 EF hand associated Thioredoxin_4 PF13462.1 AEO70527.1 - 0.00015 21.7 0.0 0.02 14.8 0.0 2.5 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 AEO70527.1 - 0.13 11.8 6.5 1.4 8.4 2.5 2.8 2 1 0 2 2 2 0 DSBA-like thioredoxin domain NGP1NT PF08153.7 AEO70529.1 - 3.3e-49 166.1 1.1 5.4e-49 165.4 0.7 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 AEO70529.1 - 3.9e-20 71.9 0.0 3.6e-16 59.1 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO70529.1 - 6.6e-06 25.4 0.1 4.5e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AEO70529.1 - 2.8e-05 24.0 0.4 0.2 11.4 0.0 3.5 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 AEO70529.1 - 0.0005 19.2 0.0 0.00099 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 AEO70529.1 - 0.0076 15.7 0.0 0.82 9.0 0.0 3.0 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.16 AEO70529.1 - 0.023 13.9 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AviRa PF11599.3 AEO70530.1 - 0.032 13.2 0.7 0.051 12.6 0.5 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Nitroreductase PF00881.19 AEO70530.1 - 0.077 12.8 2.3 0.12 12.1 1.6 1.3 1 0 0 1 1 1 0 Nitroreductase family SPT16 PF08644.6 AEO70530.1 - 0.13 12.0 1.2 0.18 11.6 0.1 1.7 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) ABC2_membrane PF01061.19 AEO70531.1 - 1.3e-38 132.3 22.3 2.3e-38 131.4 15.4 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 AEO70531.1 - 1.9e-24 86.5 0.0 3.7e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AEO70531.1 - 4.1e-09 36.8 0.0 3.2e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 AEO70531.1 - 1e-08 34.6 22.9 1e-08 34.6 15.9 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein hEGF PF12661.2 AEO70531.1 - 3.5e-05 23.5 20.0 0.0056 16.6 1.4 4.0 3 0 0 3 3 3 2 Human growth factor-like EGF AAA_25 PF13481.1 AEO70531.1 - 5e-05 22.7 0.0 0.01 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 AEO70531.1 - 0.001 18.1 0.0 0.55 9.2 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 AEO70531.1 - 0.0067 15.9 0.1 0.015 14.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 AEO70531.1 - 0.02 14.0 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 AEO70531.1 - 0.023 15.0 0.0 0.056 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AEO70531.1 - 0.035 14.1 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.14 AEO70531.1 - 0.042 13.0 0.0 0.39 9.9 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 AEO70531.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 AEO70531.1 - 0.055 13.7 0.1 0.095 13.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AEO70531.1 - 0.066 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 AEO70531.1 - 0.1 12.5 0.0 0.33 10.9 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 AEO70531.1 - 0.11 13.3 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AEO70531.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AEO70531.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain U79_P34 PF03064.11 AEO70531.1 - 0.14 11.6 1.7 0.29 10.6 1.1 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 EGF_2 PF07974.8 AEO70531.1 - 0.61 10.3 21.3 0.22 11.7 0.7 3.7 3 0 0 3 3 3 0 EGF-like domain ABC2_membrane_2 PF12679.2 AEO70531.1 - 3.5 6.4 22.4 0.061 12.1 5.5 2.3 1 1 0 2 2 2 0 ABC-2 family transporter protein Aminotran_1_2 PF00155.16 AEO70532.1 - 9.8e-41 139.8 0.0 1.2e-40 139.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AEO70532.1 - 2.8e-08 33.2 0.0 4.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 AEO70532.1 - 5.7e-06 24.8 0.0 8.5e-06 24.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 AEO70532.1 - 8.3e-06 24.7 0.0 1.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_MocR PF12897.2 AEO70532.1 - 5.8e-05 21.8 0.0 7.3e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Alliinase_C PF04864.8 AEO70532.1 - 0.0041 15.8 0.0 0.0066 15.1 0.0 1.3 1 0 0 1 1 1 1 Allinase DegT_DnrJ_EryC1 PF01041.12 AEO70532.1 - 0.013 14.5 0.1 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Asp PF00026.18 AEO70533.1 - 5.6e-64 216.3 7.0 7.3e-64 215.9 4.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO70533.1 - 1.1e-07 31.8 1.2 6.9e-07 29.3 0.5 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 AEO70533.1 - 0.005 16.4 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 AEO70533.1 - 0.016 15.6 0.3 26 5.4 0.0 3.6 3 0 0 3 3 3 0 Aspartyl protease GTP_EFTU PF00009.22 AEO70534.1 - 4.5e-58 195.7 0.0 1.1e-57 194.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 AEO70534.1 - 4.9e-33 113.2 0.0 1.2e-32 111.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 AEO70534.1 - 1.2e-32 111.5 0.0 2.3e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 AEO70534.1 - 6.2e-22 77.2 0.0 1.5e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AEO70534.1 - 5.4e-14 52.0 0.0 1.3e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF442 PF04273.8 AEO70534.1 - 0.0054 16.5 1.2 0.24 11.2 0.0 3.4 3 0 0 3 3 3 1 Putative phosphatase (DUF442) Iso_dh PF00180.15 AEO70535.1 - 1.8e-96 323.1 0.0 2.9e-96 322.4 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase FTA2 PF13095.1 AEO70537.1 - 3e-28 98.8 0.0 3.9e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Ribosomal_S8 PF00410.14 AEO70539.1 - 4.1e-24 84.8 0.0 4.9e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Yae1_N PF09811.4 AEO70541.1 - 1.2e-12 47.1 3.9 2.5e-12 46.1 2.7 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Flavodoxin_1 PF00258.20 AEO70542.1 - 6.7e-09 35.8 0.1 1.4e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 AEO70542.1 - 6.3e-08 32.2 0.0 9.6e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 AEO70542.1 - 6.5e-06 25.7 0.0 8.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 AEO70542.1 - 0.048 13.6 0.0 0.3 11.0 0.0 2.0 1 1 1 2 2 2 0 Flavodoxin domain Flavodoxin_4 PF12682.2 AEO70542.1 - 0.055 12.8 0.0 0.21 10.9 0.0 1.9 1 1 0 1 1 1 0 Flavodoxin MFS_1 PF07690.11 AEO70543.1 - 4.5e-21 74.9 63.7 1.1e-13 50.6 22.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_fiss_reg PF05308.6 AEO70543.1 - 4.1 6.6 4.4 5.9 6.1 3.1 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Protocadherin PF08374.6 AEO70544.1 - 0.012 15.2 2.0 0.075 12.6 0.0 2.2 2 0 0 2 2 2 0 Protocadherin HAUS6_N PF14661.1 AEO70544.1 - 2.4 7.4 11.8 1.8 7.8 6.9 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Asp-B-Hydro_N PF05279.6 AEO70544.1 - 3 7.6 8.9 4.4 7.0 6.2 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CAF-1_p150 PF11600.3 AEO70544.1 - 3.6 6.9 16.4 5.5 6.3 11.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal APG6 PF04111.7 AEO70544.1 - 9.3 5.1 7.4 14 4.5 5.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Methyltransf_6 PF03737.10 AEO70545.1 - 1.3e-29 103.1 0.0 1.6e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase DUF2917 PF11142.3 AEO70545.1 - 0.027 13.6 0.1 0.075 12.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) MFS_1 PF07690.11 AEO70546.1 - 1e-24 86.9 49.8 1e-24 86.9 34.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 AEO70547.1 - 1.1e-11 44.1 0.1 1.5e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain APH PF01636.18 AEO70548.1 - 1.1e-17 64.5 0.0 1.7e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 AEO70548.1 - 4.1e-05 22.4 0.0 6e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 AEO70548.1 - 0.0012 18.0 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 AEO70548.1 - 0.0029 17.2 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Abhydrolase_6 PF12697.2 AEO70549.1 - 5.4e-10 39.5 0.5 0.00071 19.5 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO70549.1 - 0.00029 20.6 0.0 0.00051 19.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 AEO70550.1 - 1.5e-10 40.3 10.8 1.5e-10 40.3 7.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MerC PF03203.9 AEO70550.1 - 0.23 11.8 2.7 2.2 8.6 1.8 2.5 1 1 0 1 1 1 0 MerC mercury resistance protein DUF3112 PF11309.3 AEO70550.1 - 0.63 9.8 6.9 1.4 8.7 0.1 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3112) NfeD PF01957.13 AEO70550.1 - 9 6.4 8.8 0.21 11.7 0.2 2.3 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding adh_short PF00106.20 AEO70552.1 - 3.9e-20 72.4 0.6 5.6e-20 71.9 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO70552.1 - 3.6e-16 59.6 0.0 4.2e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO70552.1 - 3.3e-11 43.1 0.4 4.6e-11 42.7 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO70552.1 - 1.8e-07 30.8 0.1 4.9e-07 29.4 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 AEO70552.1 - 5.3e-07 29.0 0.0 0.00051 19.2 0.0 2.4 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 AEO70552.1 - 8.8e-06 25.8 0.4 0.0001 22.3 0.3 2.3 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 AEO70552.1 - 0.078 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Sod_Cu PF00080.15 AEO70553.1 - 3.6e-12 46.6 0.2 6.8e-12 45.7 0.1 1.4 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Ribosomal_L44 PF00935.14 AEO70554.1 - 3e-35 120.0 10.8 4.3e-35 119.5 7.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 NOB1_Zn_bind PF08772.6 AEO70554.1 - 0.014 15.2 1.2 0.014 15.2 0.8 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF3433 PF11915.3 AEO70555.1 - 2.4e-20 72.4 29.8 4.4e-12 45.9 0.4 6.1 5 1 0 5 5 5 3 Protein of unknown function (DUF3433) GFO_IDH_MocA PF01408.17 AEO70556.1 - 5.6e-19 68.8 0.0 8.8e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 AEO70556.1 - 1.6e-09 37.5 0.0 3.6e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 AEO70556.1 - 0.00057 20.2 0.0 0.00098 19.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AAA_33 PF13671.1 AEO70556.1 - 0.0047 16.8 0.0 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain bZIP_1 PF00170.16 AEO70557.1 - 0.00012 21.9 6.4 0.00012 21.9 4.4 1.8 2 0 0 2 2 2 1 bZIP transcription factor Ebola_NP PF05505.7 AEO70557.1 - 0.4 8.6 2.3 0.56 8.1 1.6 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein RRM_1 PF00076.17 AEO70558.1 - 5.2e-14 51.6 0.0 1.1e-13 50.6 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO70558.1 - 6.7e-12 45.2 0.0 1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO70558.1 - 4.9e-07 29.5 0.0 7.7e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_3 PF00933.16 AEO70559.1 - 4.4e-55 186.7 0.0 6e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO70559.1 - 5.6e-41 140.5 0.0 1.7e-40 138.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO70559.1 - 5.4e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain ADH_zinc_N PF00107.21 AEO70560.1 - 1.3e-07 31.2 0.2 2.2e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO70560.1 - 7.7e-06 25.6 0.0 2.6e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 AEO70560.1 - 0.012 15.1 0.7 0.022 14.3 0.4 1.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 AEO70560.1 - 0.034 13.7 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NmrA PF05368.8 AEO70560.1 - 0.12 11.6 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family MFS_1 PF07690.11 AEO70561.1 - 2.6e-38 131.6 63.9 2.6e-38 131.6 44.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO70561.1 - 4.8e-16 58.0 23.6 6.3e-16 57.6 16.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 AEO70561.1 - 8.9e-14 50.9 10.9 8.9e-14 50.9 7.5 3.3 2 1 0 3 3 3 2 Sugar (and other) transporter Pex14_N PF04695.8 AEO70561.1 - 0.015 15.3 0.8 3.4 7.7 0.3 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HMG-CoA_red PF00368.13 AEO70562.1 - 3e-157 523.0 6.4 3.9e-157 522.6 4.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 AEO70562.1 - 1.9e-44 151.0 0.7 3.2e-44 150.2 0.5 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 AEO70562.1 - 1.3e-11 44.1 5.3 1e-10 41.2 3.7 2.2 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 AEO70562.1 - 5.9e-05 21.2 3.7 9.8e-05 20.4 2.6 1.3 1 0 0 1 1 1 1 Patched family Lig_chan PF00060.21 AEO70562.1 - 0.14 11.9 1.1 2.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Ligand-gated ion channel LysM PF01476.15 AEO70563.1 - 2.6e-38 129.6 0.3 2.2e-06 27.4 0.0 5.3 5 0 0 5 5 5 5 LysM domain LRRNT_2 PF08263.7 AEO70563.1 - 0.41 10.6 24.4 2.5 8.1 0.3 4.7 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain RCC_reductase PF06405.6 AEO70563.1 - 0.95 8.3 3.1 56 2.5 0.0 3.6 4 0 0 4 4 4 0 Red chlorophyll catabolite reductase (RCC reductase) Med3 PF11593.3 AEO70563.1 - 0.99 8.5 10.7 1.6 7.9 7.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CBM_14 PF01607.19 AEO70563.1 - 5.1 7.1 17.3 17 5.4 0.1 6.1 8 0 0 8 8 8 0 Chitin binding Peritrophin-A domain Glyco_hydro_18 PF00704.23 AEO70565.1 - 1e-47 163.2 0.9 1.9e-47 162.4 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.1 AEO70565.1 - 5e-31 106.4 2.0 5e-31 106.4 1.4 3.4 3 0 0 3 3 3 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.15 AEO70565.1 - 1.2e-08 34.7 0.4 0.0011 18.7 0.0 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 AEO70565.1 - 0.00085 19.2 5.0 0.00085 19.2 3.5 4.3 5 0 0 5 5 5 1 Chitin recognition protein Isochorismatase PF00857.15 AEO70566.1 - 8.1e-30 104.0 0.0 1.6e-29 103.0 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family TPR_11 PF13414.1 AEO70567.1 - 0.0011 18.5 0.1 0.0013 18.3 0.0 1.1 1 0 0 1 1 1 1 TPR repeat p450 PF00067.17 AEO70569.1 - 1.9e-25 89.3 0.0 2.6e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 AEO70570.1 - 1.2e-32 113.0 21.8 1.2e-32 113.0 15.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_pol_Rpc34 PF05158.7 AEO70571.1 - 2e-115 385.4 0.0 4.1e-100 335.1 0.0 2.0 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit RPA_C PF08784.6 AEO70571.1 - 3e-05 24.3 0.7 0.022 15.1 0.0 3.1 3 1 0 3 3 3 2 Replication protein A C terminal HTH_34 PF13601.1 AEO70571.1 - 0.002 18.1 0.0 0.0058 16.6 0.0 1.8 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_36 PF13730.1 AEO70571.1 - 0.015 15.3 0.1 0.054 13.6 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain B-block_TFIIIC PF04182.7 AEO70571.1 - 0.045 13.5 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC MarR PF01047.17 AEO70571.1 - 0.086 12.5 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 MarR family Ribosomal_S25 PF03297.10 AEO70571.1 - 0.12 12.3 0.0 0.74 9.8 0.0 2.0 2 0 0 2 2 2 0 S25 ribosomal protein DUF3944 PF13099.1 AEO70571.1 - 0.35 10.3 0.1 0.35 10.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) Pro_isomerase PF00160.16 AEO70572.1 - 1.2e-41 142.4 0.2 1.5e-41 142.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.15 AEO70573.1 - 4e-49 165.6 0.4 5.4e-49 165.1 0.3 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 AEO70573.1 - 0.0002 20.2 0.2 0.00026 19.8 0.1 1.1 1 0 0 1 1 1 1 ANTH domain BAR PF03114.13 AEO70573.1 - 0.45 9.9 3.7 16 4.9 3.3 2.1 1 1 0 1 1 1 0 BAR domain GRP PF07172.6 AEO70573.1 - 9.7 6.7 25.1 0.058 13.8 11.3 1.8 2 0 0 2 2 2 0 Glycine rich protein family GILT PF03227.11 AEO70574.1 - 0.17 11.7 1.9 12 5.7 0.1 2.2 2 0 0 2 2 2 0 Gamma interferon inducible lysosomal thiol reductase (GILT) Fer4_4 PF12800.2 AEO70574.1 - 0.85 10.1 11.7 3 8.4 0.8 2.6 3 0 0 3 3 3 0 4Fe-4S binding domain TNFR_c6 PF00020.13 AEO70574.1 - 1.6 8.8 12.0 1.5 8.9 0.7 2.5 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region EndIII_4Fe-2S PF10576.4 AEO70574.1 - 2.8 8.2 10.8 4.2 7.7 0.6 3.1 3 0 0 3 3 3 0 Iron-sulfur binding domain of endonuclease III Fer4_17 PF13534.1 AEO70574.1 - 7.1 7.0 10.2 33 4.9 7.1 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain PT PF04886.7 AEO70575.1 - 1.5 8.2 13.3 0.1 11.9 2.5 2.6 3 0 0 3 3 3 0 PT repeat Fungal_trans_2 PF11951.3 AEO70578.1 - 7.9e-53 179.4 0.6 1e-52 179.0 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO70578.1 - 1.2e-08 34.7 4.6 1.2e-08 34.7 3.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EH_Signature PF15611.1 AEO70578.1 - 0.029 13.4 0.3 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 EH_Signature domain Hemerythrin PF01814.18 AEO70579.1 - 1.2e-09 38.4 0.6 1.8e-09 37.8 0.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain NACHT PF05729.7 AEO70580.1 - 9.2e-11 41.6 0.0 2.1e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 AEO70580.1 - 9.8e-08 32.1 1.7 1.2e-06 28.7 0.7 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AEO70580.1 - 1.1e-06 28.8 0.0 6.4e-06 26.3 0.0 2.3 3 0 0 3 3 3 1 AAA domain Acetyltransf_1 PF00583.19 AEO70580.1 - 5.5e-05 23.1 0.0 0.001 19.0 0.0 3.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AEO70580.1 - 0.00017 21.7 0.4 0.0045 17.0 0.0 3.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO70580.1 - 0.0014 18.7 0.0 0.0041 17.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NB-ARC PF00931.17 AEO70580.1 - 0.0062 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.4 AEO70580.1 - 0.0066 15.4 0.1 0.018 14.0 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DUF550 PF04447.7 AEO70580.1 - 0.012 15.2 0.2 0.098 12.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF550) RNA_helicase PF00910.17 AEO70580.1 - 0.056 13.6 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase BAR_3_WASP_bdg PF10456.4 AEO70580.1 - 0.16 11.1 0.1 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein AAA PF00004.24 AEO70580.1 - 0.17 12.1 0.0 0.6 10.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SET PF00856.23 AEO70581.1 - 7.4e-15 55.6 0.0 2.6e-13 50.6 0.0 2.5 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 AEO70581.1 - 7.8e-12 44.6 14.8 2.6e-07 30.2 1.4 3.5 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 AEO70581.1 - 9.9e-08 31.3 13.0 0.0047 16.7 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 AEO70581.1 - 0.037 14.3 8.2 3.5 8.0 0.1 3.6 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO70581.1 - 0.18 12.5 19.4 4 8.3 0.4 6.5 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 AEO70581.1 - 1.3 9.0 9.4 12 5.9 0.1 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 AEO70581.1 - 7.6 7.0 5.9 84 3.7 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat SET PF00856.23 AEO70584.1 - 5.6e-13 49.5 0.1 4e-12 46.7 0.1 2.3 1 1 0 1 1 1 1 SET domain SAF PF08666.7 AEO70584.1 - 0.028 14.8 0.0 3.7 8.0 0.0 2.4 2 0 0 2 2 2 0 SAF domain SUR7 PF06687.7 AEO70585.1 - 6.8e-16 58.4 5.7 8.2e-16 58.2 4.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family Tic20 PF09685.5 AEO70585.1 - 3.6 7.6 14.6 0.63 10.0 5.7 2.4 2 1 0 2 2 2 0 Tic20-like protein AMP-binding PF00501.23 AEO70586.1 - 3.7e-77 259.4 0.0 6.8e-77 258.6 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 AEO70586.1 - 8.4e-68 227.9 0.0 1.3e-67 227.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 AEO70586.1 - 3.7e-13 49.4 0.0 7.4e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 AEO70586.1 - 2.6e-12 46.8 0.0 5.2e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 AEO70586.1 - 6.9e-09 34.7 0.1 1.9e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 AEO70586.1 - 3.2e-08 34.4 0.0 2.3e-07 31.6 0.0 2.6 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 AEO70586.1 - 0.00021 21.2 2.3 0.0013 18.7 0.7 2.8 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 AEO70586.1 - 0.0015 17.5 0.0 0.0042 16.0 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 AEO70586.1 - 0.011 14.6 0.1 0.19 10.5 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.5 AEO70586.1 - 0.057 13.0 0.4 0.26 10.9 0.3 2.1 1 1 0 1 1 1 0 KR domain Peptidase_S28 PF05577.7 AEO70587.1 - 2e-42 145.3 0.1 3.3e-42 144.5 0.1 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 AEO70587.1 - 8.2e-05 22.5 1.6 0.00011 22.1 0.3 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Pkinase PF00069.20 AEO70589.1 - 1.2e-72 244.2 0.0 1.9e-72 243.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO70589.1 - 1e-35 123.0 0.0 2.7e-35 121.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO70589.1 - 0.00037 19.5 0.3 0.84 8.5 0.0 2.6 2 0 0 2 2 2 2 Kinase-like Peptidase_S8 PF00082.17 AEO70591.1 - 6.2e-15 55.0 0.1 1.4e-14 53.9 0.0 1.5 1 1 0 1 1 1 1 Subtilase family Dynamin_N PF00350.18 AEO70592.1 - 1e-29 103.5 0.0 1.8e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 AEO70592.1 - 1.1e-15 57.1 0.0 3.7e-15 55.4 0.0 1.8 3 0 0 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.18 AEO70592.1 - 0.00012 21.9 0.0 0.0016 18.3 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Phage_tail_X PF05489.7 AEO70592.1 - 0.0016 17.9 0.0 0.0089 15.4 0.0 2.3 3 0 0 3 3 3 1 Phage Tail Protein X GED PF02212.13 AEO70592.1 - 0.011 15.6 0.8 0.033 14.0 0.1 2.2 2 0 0 2 2 2 0 Dynamin GTPase effector domain FtsK_SpoIIIE PF01580.13 AEO70592.1 - 0.012 15.1 0.0 0.046 13.1 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family FeoB_N PF02421.13 AEO70592.1 - 0.019 14.2 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B BMFP PF04380.8 AEO70592.1 - 0.042 13.9 1.4 0.22 11.6 0.3 2.7 2 0 0 2 2 2 0 Membrane fusogenic activity AAA_21 PF13304.1 AEO70592.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 AEO70592.1 - 0.048 14.1 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 AEO70592.1 - 0.059 12.9 1.1 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zn_clus PF00172.13 AEO70593.1 - 1.3e-06 28.1 7.7 3.3e-06 26.8 5.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO70593.1 - 3.7e-06 25.8 1.8 5.7e-06 25.1 1.3 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 AEO70594.1 - 1.2e-76 257.2 0.0 1.4e-76 257.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.7 AEO70595.1 - 9.5e-08 31.7 0.0 9.3e-07 28.5 0.0 2.5 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO70595.1 - 1.6e-05 24.4 1.9 0.00042 19.8 1.3 2.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO70595.1 - 2.2e-05 25.3 0.2 7.6e-05 23.6 0.1 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FMN_dh PF01070.13 AEO70595.1 - 0.028 13.2 0.3 0.041 12.7 0.2 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase AlaDh_PNT_C PF01262.16 AEO70595.1 - 0.064 12.8 0.3 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2OG-FeII_Oxy_3 PF13640.1 AEO70596.1 - 0.0016 18.8 0.1 0.0031 18.0 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 AEO70596.1 - 0.032 14.5 0.0 0.48 10.7 0.0 2.2 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.9 AEO70597.1 - 7.9e-39 133.8 2.1 1.2e-38 133.2 1.5 1.2 1 0 0 1 1 1 1 Amidohydrolase Aldedh PF00171.17 AEO70598.1 - 1.8e-142 474.9 0.0 2.3e-142 474.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sec5 PF15469.1 AEO70598.1 - 0.22 11.2 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 Ribonuc_L-PSP PF01042.16 AEO70599.1 - 7.4e-18 64.4 0.0 1.1e-17 63.9 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP Methyltransf_3 PF01596.12 AEO70600.1 - 3e-17 62.3 0.0 4.1e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 AEO70600.1 - 1.6e-12 48.2 0.0 2.3e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO70600.1 - 0.019 14.9 0.0 0.048 13.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain ketoacyl-synt PF00109.21 AEO70601.1 - 3.6e-71 239.6 0.0 9e-71 238.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 AEO70601.1 - 4.3e-47 160.9 0.0 6.5e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Thioesterase PF00975.15 AEO70601.1 - 3.4e-33 115.7 0.0 1.8e-32 113.3 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 AEO70601.1 - 4.1e-31 107.2 0.2 9.3e-31 106.1 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 AEO70601.1 - 5.8e-20 71.6 0.7 1.7e-19 70.1 0.5 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 AEO70601.1 - 1.9e-09 37.6 0.0 5.3e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 AEO70601.1 - 3.5e-08 33.3 0.1 0.00066 19.4 0.0 3.1 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO70601.1 - 3.9e-07 30.1 0.1 0.00088 19.2 0.0 3.0 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 AEO70601.1 - 2.8e-05 23.2 0.0 5.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_3 PF07859.8 AEO70601.1 - 0.0081 15.7 0.0 1.2 8.6 0.0 3.3 3 0 0 3 3 3 1 alpha/beta hydrolase fold Pro_CA PF00484.14 AEO70602.1 - 1.8e-19 70.2 0.0 2.2e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase HGD-D PF06050.8 AEO70602.1 - 0.13 11.0 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component NmrA PF05368.8 AEO70603.1 - 6.7e-18 64.7 0.0 8.6e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO70603.1 - 7.9e-12 45.5 0.0 1.2e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 AEO70603.1 - 0.0011 18.0 0.0 0.0018 17.3 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase Fungal_trans PF04082.13 AEO70604.1 - 4e-09 35.7 0.0 6.1e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO70604.1 - 1.8e-07 30.9 11.3 4e-07 29.8 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 AEO70605.1 - 3.7e-31 108.1 48.8 2.4e-21 75.8 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 AEO70606.1 - 2.9e-07 30.2 8.2 6.7e-07 29.1 5.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CPSF100_C PF13299.1 AEO70606.1 - 0.26 11.4 3.1 0.2 11.8 0.2 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Mucin PF01456.12 AEO70606.1 - 0.3 10.8 34.1 0.77 9.5 15.1 2.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Pol_alpha_B_N PF08418.5 AEO70606.1 - 1.5 8.2 14.0 0.74 9.3 2.2 2.5 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal FAD_binding_3 PF01494.14 AEO70607.1 - 9e-18 64.4 0.6 1.7e-16 60.2 0.4 2.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO70607.1 - 5.1e-09 35.5 2.0 6.4e-08 31.8 0.9 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO70607.1 - 1e-07 31.8 0.3 2.6e-07 30.5 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 AEO70607.1 - 3.3e-06 26.2 0.9 4.9e-06 25.6 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AEO70607.1 - 4e-06 26.8 0.2 7.4e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ADC PF06314.6 AEO70607.1 - 2.4e-05 23.7 0.0 3.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Trp_halogenase PF04820.9 AEO70607.1 - 2.6e-05 23.0 0.9 0.00015 20.5 0.1 2.0 1 1 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 AEO70607.1 - 0.00025 21.4 0.2 0.00083 19.7 0.1 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO70607.1 - 0.00076 18.6 0.1 0.0015 17.6 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 AEO70607.1 - 0.0014 17.5 0.3 0.0021 16.9 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 AEO70607.1 - 0.0016 16.9 0.3 0.0024 16.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.16 AEO70607.1 - 0.002 17.7 0.4 0.0041 16.7 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 AEO70607.1 - 0.0022 16.9 0.2 1.3 7.8 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.12 AEO70607.1 - 0.008 15.2 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 AEO70607.1 - 0.0085 15.2 0.2 0.039 13.0 0.1 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase ApbA PF02558.11 AEO70607.1 - 0.013 14.9 0.3 0.024 14.0 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 AEO70607.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 AEO70607.1 - 0.22 10.8 0.1 0.72 9.1 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 AEO70607.1 - 0.29 10.7 0.9 0.47 10.0 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AA_permease PF00324.16 AEO70608.1 - 4.1e-121 404.6 40.6 4.6e-121 404.4 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO70608.1 - 7.3e-28 97.2 45.4 9.9e-28 96.8 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF668 PF05003.7 AEO70609.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF668) DUF4599 PF15371.1 AEO70609.1 - 0.14 12.2 1.0 0.37 10.8 0.0 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4599) Amidoligase_2 PF12224.3 AEO70610.1 - 6.7e-15 55.3 0.0 8.9e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme Peptidase_A4 PF01828.12 AEO70613.1 - 1.8e-60 203.5 3.5 2.2e-60 203.3 2.5 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF1212 PF06738.7 AEO70614.1 - 4.8e-53 179.5 1.3 1.6e-51 174.5 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 AEO70614.1 - 7.5e-19 67.9 29.2 5.1e-11 42.6 0.7 3.6 3 1 0 3 3 3 3 Protein of unknown function (DUF3815) DUF2301 PF10063.4 AEO70614.1 - 0.3 11.3 4.6 0.75 10.0 3.2 1.6 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) SSP160 PF06933.6 AEO70614.1 - 0.74 7.7 14.6 1.2 7.0 10.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Hist_deacetyl PF00850.14 AEO70615.1 - 5.3e-77 259.1 0.0 9.4e-77 258.3 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.16 AEO70616.1 - 1e-35 121.9 0.2 2.4e-35 120.6 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 AEO70616.1 - 3.5e-27 94.7 0.8 6.9e-27 93.8 0.5 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 AEO70616.1 - 7.6e-09 35.0 0.0 1.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Chordopox_A13L PF05961.6 AEO70616.1 - 0.064 13.1 0.2 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Methyltransf_18 PF12847.2 AEO70618.1 - 1.3e-11 45.0 0.1 1.9e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO70618.1 - 4.4e-08 33.0 0.0 5.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO70618.1 - 2e-06 28.1 0.0 4.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO70618.1 - 2.9e-06 27.6 0.0 4.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO70618.1 - 7.8e-06 25.9 0.1 1.6e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO70618.1 - 0.0001 21.9 0.0 0.00016 21.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO70618.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 AEO70618.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 1 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 AEO70618.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 AEO70618.1 - 0.17 11.0 0.0 10 5.2 0.0 2.3 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G DUF605 PF04652.11 AEO70620.1 - 9e-87 291.9 30.3 4.2e-58 197.5 13.2 2.0 2 0 0 2 2 2 2 Vta1 like FKBP_N PF01346.13 AEO70620.1 - 0.12 12.4 1.4 0.23 11.5 1.0 1.4 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Thioredoxin PF00085.15 AEO70621.1 - 7.4e-31 105.9 0.1 1.3e-24 85.8 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 AEO70621.1 - 4.8e-09 36.2 0.0 4e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AEO70621.1 - 3.1e-06 27.2 0.1 0.0046 17.0 0.0 4.5 3 2 2 5 5 5 1 Thioredoxin-like Thioredoxin_2 PF13098.1 AEO70621.1 - 3.5e-06 27.1 6.7 3.4e-05 23.9 1.3 3.2 2 1 0 2 2 2 1 Thioredoxin-like domain FAIM1 PF06905.8 AEO70621.1 - 0.0049 16.0 0.1 0.0088 15.2 0.0 1.3 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) Thioredoxin_7 PF13899.1 AEO70621.1 - 0.01 15.8 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like RNase_PH PF01138.16 AEO70622.1 - 1.2e-26 93.6 2.5 6.5e-14 52.3 0.1 2.3 1 1 1 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AEO70622.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 MFS_1 PF07690.11 AEO70627.1 - 1.6e-12 46.8 33.4 4.5e-11 42.0 23.1 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 AEO70627.1 - 4.4e-05 21.7 13.3 0.0029 15.7 1.1 2.8 2 1 1 3 3 3 2 Transmembrane secretion effector DUF3370 PF11850.3 AEO70628.1 - 0.076 11.4 0.0 0.094 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3370) RPE65 PF03055.10 AEO70629.1 - 1.7e-103 346.7 0.0 2e-103 346.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Glycophorin_A PF01102.13 AEO70630.1 - 0.00063 19.4 1.1 0.0013 18.4 0.7 1.5 1 0 0 1 1 1 1 Glycophorin A Adeno_E3_CR2 PF02439.10 AEO70630.1 - 0.0054 16.2 0.3 0.011 15.2 0.2 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 AEO70630.1 - 0.024 15.0 0.1 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4328 PF14219.1 AEO70630.1 - 0.043 13.1 0.0 0.094 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF1517 PF07466.6 AEO70630.1 - 0.071 12.0 3.3 0.1 11.5 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF1180 PF06679.7 AEO70630.1 - 0.072 12.9 2.4 0.13 12.1 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SCF PF02404.10 AEO70630.1 - 0.12 11.5 2.1 0.17 11.0 1.4 1.2 1 0 0 1 1 1 0 Stem cell factor CAP59_mtransfer PF11735.3 AEO70631.1 - 1.8e-62 210.6 0.0 2.4e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Sugar_tr PF00083.19 AEO70632.1 - 1e-99 334.2 24.9 1.2e-99 333.9 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO70632.1 - 1.4e-25 89.7 31.1 2.8e-17 62.4 6.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily IlvC PF01450.14 AEO70632.1 - 0.16 11.9 0.0 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain adh_short PF00106.20 AEO70635.1 - 1.4e-07 31.6 0.3 1.8e-07 31.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 AEO70635.1 - 2.5e-05 24.3 1.2 3.8e-05 23.7 0.8 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 AEO70635.1 - 0.0013 18.4 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 AEO70635.1 - 0.0031 16.8 1.8 0.0047 16.2 1.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 AEO70635.1 - 0.097 12.0 0.6 0.16 11.3 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 AEO70636.1 - 1.8e-31 109.7 0.1 2.2e-31 109.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AEO70636.1 - 3.3e-30 105.2 5.4 4.1e-30 104.8 3.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO70636.1 - 1.6e-15 57.2 3.2 2.4e-15 56.6 2.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO70636.1 - 6.8e-07 28.9 0.3 3.2e-06 26.7 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 AEO70636.1 - 1.5e-05 24.0 0.4 2e-05 23.6 0.3 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 AEO70636.1 - 0.00092 19.2 3.1 0.0022 18.0 2.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 AEO70636.1 - 0.0052 15.5 0.2 0.0078 14.9 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 AEO70636.1 - 0.045 13.5 0.7 0.09 12.5 0.5 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase VWA_2 PF13519.1 AEO70636.1 - 0.046 13.8 0.3 0.23 11.5 0.2 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain F420_oxidored PF03807.12 AEO70636.1 - 0.059 13.8 0.5 0.12 12.7 0.4 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.14 AEO70636.1 - 0.059 12.4 0.1 0.12 11.4 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 AEO70636.1 - 0.11 11.5 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF4235 PF14019.1 AEO70636.1 - 0.18 11.6 0.2 0.18 11.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) AdoHcyase_NAD PF00670.16 AEO70636.1 - 0.37 10.6 2.2 0.75 9.6 1.5 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ETF PF01012.16 AEO70636.1 - 5.6 6.6 8.1 1.3 8.7 2.1 2.3 2 1 1 3 3 3 0 Electron transfer flavoprotein domain MFS_1 PF07690.11 AEO70637.1 - 3.6e-32 111.4 37.2 6.8e-32 110.5 25.8 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2205 PF10224.4 AEO70638.1 - 1.4e-31 107.8 3.1 1.8e-31 107.5 2.2 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF4200 PF13863.1 AEO70638.1 - 0.0032 17.4 1.0 0.0041 17.0 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) AAA_32 PF13654.1 AEO70638.1 - 0.0057 15.3 0.3 0.0066 15.1 0.2 1.0 1 0 0 1 1 1 1 AAA domain Terpene_synth_C PF03936.11 AEO70638.1 - 0.047 12.9 0.1 0.054 12.7 0.0 1.1 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain AA_permease_2 PF13520.1 AEO70639.1 - 1.5e-59 201.6 38.0 1.8e-59 201.4 26.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO70639.1 - 1e-25 90.0 40.8 1.4e-24 86.3 28.3 2.0 1 1 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.19 AEO70640.1 - 1.7e-81 274.1 18.6 1.9e-81 273.9 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO70640.1 - 3.1e-30 105.0 19.7 4.5e-30 104.5 13.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO70640.1 - 0.00044 18.5 2.1 0.00058 18.1 0.9 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 AEO70640.1 - 0.00098 17.6 19.2 0.011 14.1 6.8 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 AEO70640.1 - 0.023 12.8 9.2 0.014 13.5 0.8 2.9 2 1 0 2 2 2 0 Transmembrane secretion effector Na_Ca_ex PF01699.19 AEO70642.1 - 3e-40 137.0 36.0 1.8e-21 76.2 9.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1707 PF08044.6 AEO70643.1 - 0.0082 15.8 0.1 0.017 14.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) WD40 PF00400.27 AEO70644.1 - 9.1e-48 158.5 16.6 2.7e-16 58.7 0.4 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 AEO70644.1 - 4.2e-05 21.9 0.2 0.36 8.9 0.0 3.1 1 1 1 3 3 3 2 Nucleoporin Nup120/160 NLE PF08154.7 AEO70644.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 NLE (NUC135) domain eIF2A PF08662.6 AEO70644.1 - 0.014 15.1 0.0 0.27 10.9 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Glyco_transf_20 PF00982.16 AEO70645.1 - 6e-164 546.0 0.0 8.4e-164 545.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 AEO70645.1 - 1.6e-44 151.5 0.0 2.6e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 AEO70645.1 - 0.0025 17.3 0.3 0.0052 16.3 0.2 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain DUF4295 PF14128.1 AEO70645.1 - 0.02 14.5 0.7 0.039 13.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4295) Aminotran_4 PF01063.14 AEO70646.1 - 2.4e-23 82.8 0.0 3.3e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV MutS_V PF00488.16 AEO70647.1 - 1.8e-70 237.0 0.0 3e-70 236.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AEO70647.1 - 4.1e-28 98.5 0.5 1.3e-27 96.9 0.4 1.8 1 1 0 1 1 1 1 MutS domain III MutS_II PF05188.12 AEO70647.1 - 0.0077 16.2 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain II DUF2765 PF10963.3 AEO70647.1 - 0.12 12.3 0.1 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2765) DUF221 PF02714.10 AEO70648.1 - 2.1e-93 312.7 13.6 3.1e-93 312.1 9.4 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AEO70648.1 - 5.4e-42 143.0 0.2 5.4e-42 143.0 0.2 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 AEO70648.1 - 2.6e-16 59.8 0.0 4.9e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) 2-Hacid_dh_C PF02826.14 AEO70649.1 - 3.1e-55 186.0 0.0 4.6e-55 185.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AEO70649.1 - 3.5e-28 97.7 0.0 4.3e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AEO70649.1 - 5.3e-05 23.1 0.0 9.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 AEO70649.1 - 7.3e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 AEO70649.1 - 0.0024 17.2 0.0 0.016 14.5 0.0 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain CoA_binding_2 PF13380.1 AEO70649.1 - 0.015 15.4 0.1 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain MFS_1 PF07690.11 AEO70651.1 - 1.2e-34 119.6 32.4 1.7e-34 119.0 22.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 AEO70652.1 - 8e-15 55.4 0.0 2.4e-14 53.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AEO70652.1 - 5.3e-14 51.3 0.0 1.7e-13 49.6 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 AEO70652.1 - 3e-10 39.9 2.2 4.4e-09 36.2 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 AEO70652.1 - 3.2e-09 36.7 0.2 9.2e-08 32.0 0.1 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 AEO70652.1 - 7.1e-07 29.3 0.0 4.5e-06 26.6 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO70652.1 - 3.5e-05 22.8 0.0 0.0012 17.8 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 AEO70652.1 - 0.00017 20.6 0.0 0.00038 19.4 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 AEO70652.1 - 0.00068 18.8 0.0 0.029 13.4 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 AEO70652.1 - 0.0032 17.8 0.4 5.5 7.4 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO70652.1 - 0.0073 15.4 0.0 0.02 13.9 0.0 1.7 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 AEO70652.1 - 0.022 13.2 0.0 0.037 12.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 AEO70652.1 - 0.029 13.4 0.5 0.069 12.1 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Dicty_CAR PF05462.6 AEO70653.1 - 3.6e-09 35.9 7.0 5.8e-09 35.2 4.8 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.3 AEO70653.1 - 1.6e-07 31.0 10.8 2.6e-07 30.3 7.5 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 TMEM190 PF15431.1 AEO70653.1 - 0.0032 17.3 1.0 0.24 11.3 0.3 2.3 1 1 1 2 2 2 1 Transmembrane protein 190 Med3 PF11593.3 AEO70653.1 - 0.52 9.4 8.6 0.68 9.1 6.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CD20 PF04103.10 AEO70653.1 - 7.9 6.3 11.9 0.09 12.7 2.2 2.2 3 0 0 3 3 3 0 CD20-like family Alpha-amylase PF00128.19 AEO70654.1 - 6.5e-98 328.0 0.0 8.6e-98 327.6 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.3 AEO70654.1 - 0.001 19.1 0.1 0.0027 17.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) hDGE_amylase PF14701.1 AEO70654.1 - 0.0022 16.9 0.0 0.0038 16.1 0.0 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Glyoxalase_2 PF12681.2 AEO70654.1 - 0.092 13.3 0.0 0.3 11.7 0.0 1.8 1 0 0 1 1 1 0 Glyoxalase-like domain Steroid_dh PF02544.11 AEO70655.1 - 3.4e-15 56.0 0.4 3.4e-15 56.0 0.3 1.8 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 AEO70655.1 - 7.8e-05 22.0 5.6 0.00019 20.8 3.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 AEO70655.1 - 0.016 15.2 0.1 0.016 15.2 0.1 2.5 2 0 0 2 2 2 0 Phospholipid methyltransferase Serglycin PF04360.7 AEO70656.1 - 0.41 10.3 0.0 0.41 10.3 0.0 2.8 1 1 1 2 2 2 0 Serglycin Erv26 PF04148.8 AEO70657.1 - 3.1e-91 304.4 1.5 3.5e-91 304.2 1.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF3377 PF11857.3 AEO70657.1 - 0.088 12.4 0.0 0.088 12.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Claudin_2 PF13903.1 AEO70657.1 - 0.27 10.8 5.7 0.083 12.5 1.0 1.9 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction WBS_methylT PF12589.3 AEO70658.1 - 4.5e-18 65.5 6.3 7.8e-18 64.7 4.4 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 AEO70658.1 - 2.9e-10 40.5 0.0 5.5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO70658.1 - 4.8e-07 30.0 0.0 1e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO70658.1 - 9.7e-06 25.2 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AEO70658.1 - 8.8e-05 22.1 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 AEO70658.1 - 0.00012 22.6 0.0 0.00029 21.3 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO70658.1 - 0.00012 21.8 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO70658.1 - 0.00016 22.0 0.0 0.00043 20.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AEO70658.1 - 0.0014 17.7 0.0 0.013 14.6 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 AEO70658.1 - 0.0017 18.3 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO70658.1 - 0.01 14.9 0.0 0.023 13.8 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Tyrosinase PF00264.15 AEO70659.1 - 9.1e-58 196.0 1.5 9.1e-58 196.0 1.1 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase Iso_dh PF00180.15 AEO70660.1 - 4.9e-81 272.3 0.0 5.7e-81 272.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pkinase PF00069.20 AEO70664.1 - 2e-69 233.6 0.0 2.9e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO70664.1 - 2.6e-50 170.9 0.0 3.9e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO70664.1 - 0.00051 19.0 0.0 0.0032 16.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like PAT1 PF09770.4 AEO70664.1 - 0.44 8.7 18.7 0.62 8.2 13.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Thioredoxin_7 PF13899.1 AEO70665.1 - 4.2e-15 55.5 0.1 9.4e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 AEO70665.1 - 2.1e-08 33.5 0.5 4.7e-08 32.4 0.3 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 AEO70665.1 - 3.5e-08 33.3 0.0 7.2e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.10 AEO70665.1 - 0.0041 16.8 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 ELL PF10390.4 AEO70665.1 - 0.033 13.4 0.1 3 6.9 0.0 2.2 1 1 0 2 2 2 0 RNA polymerase II elongation factor ELL Thioredoxin_2 PF13098.1 AEO70665.1 - 0.038 14.2 0.1 0.13 12.5 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Ecm29 PF13001.2 AEO70666.1 - 9.8e-70 235.4 0.0 1.7e-69 234.6 0.0 1.4 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 AEO70666.1 - 0.00019 21.2 5.4 1 9.6 0.0 6.9 7 0 0 7 7 7 1 HEAT repeat RRM_1 PF00076.17 AEO70667.1 - 1.9e-44 149.1 0.0 1.4e-16 59.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO70667.1 - 4.4e-25 87.4 0.0 5.7e-10 39.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO70667.1 - 1.7e-20 72.5 0.0 1.2e-08 34.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AEO70667.1 - 2.1e-06 27.5 0.0 0.00014 21.6 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 AEO70667.1 - 5.8e-05 22.7 0.1 0.0032 17.2 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif IncA PF04156.9 AEO70671.1 - 0.039 13.5 0.2 0.039 13.5 0.1 1.7 2 0 0 2 2 2 0 IncA protein Senescence PF06911.7 AEO70672.1 - 0.17 11.5 6.1 0.21 11.2 4.2 1.1 1 0 0 1 1 1 0 Senescence-associated protein Acyl_transf_3 PF01757.17 AEO70674.1 - 2.7e-24 85.6 31.4 4.8e-24 84.8 21.7 1.5 1 1 0 1 1 1 1 Acyltransferase family DUF4360 PF14273.1 AEO70676.1 - 1.7e-16 60.3 1.0 2.3e-16 59.9 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CytochromB561_N PF09786.4 AEO70677.1 - 0.1 11.0 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal KfrA_N PF11740.3 AEO70678.1 - 1.2 9.5 9.2 0.17 12.3 3.1 2.0 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Cellulase PF00150.13 AEO70679.1 - 2e-51 174.8 2.1 2.6e-51 174.4 1.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 AEO70679.1 - 8e-14 51.0 14.3 8e-14 51.0 9.9 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain MFS_1 PF07690.11 AEO70680.1 - 3.2e-42 144.5 35.5 3.2e-42 144.5 24.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO70680.1 - 3.5e-08 32.1 2.8 5e-08 31.6 1.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 AEO70680.1 - 1.4e-07 30.4 29.4 3.4e-07 29.2 20.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2178 PF09946.4 AEO70680.1 - 8.1e-05 22.3 0.6 8.1e-05 22.3 0.4 2.3 2 0 0 2 2 2 1 Predicted membrane protein (DUF2178) DUF1669 PF07894.7 AEO70681.1 - 0.34 10.0 1.6 0.43 9.7 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) DUF3237 PF11578.3 AEO70682.1 - 1.7e-36 124.7 0.0 2.5e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 AEO70682.1 - 1.2e-06 28.1 5.4 0.0092 15.7 0.3 2.4 2 0 0 2 2 2 2 BED zinc finger Herpes_capsid PF06112.6 AEO70682.1 - 0.0015 18.5 2.0 0.003 17.6 0.9 1.9 2 0 0 2 2 2 1 Gammaherpesvirus capsid protein zf-C2H2_2 PF12756.2 AEO70682.1 - 0.055 13.5 5.2 3.2 7.9 0.3 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) MGC-24 PF05283.6 AEO70682.1 - 0.11 12.2 6.2 0.28 10.9 4.3 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) PDT PF00800.13 AEO70682.1 - 0.63 9.5 4.9 1.1 8.7 3.4 1.3 1 0 0 1 1 1 0 Prephenate dehydratase TraV PF09676.5 AEO70682.1 - 0.96 10.1 12.5 0.55 10.9 3.2 2.6 3 0 0 3 3 3 0 Type IV conjugative transfer system lipoprotein (TraV) Med3 PF11593.3 AEO70682.1 - 1.7 7.7 4.9 2.1 7.4 3.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Zn_Tnp_IS1595 PF12760.2 AEO70682.1 - 4.5 7.1 8.5 21 5.0 0.3 3.5 3 0 0 3 3 3 0 Transposase zinc-ribbon domain HLH PF00010.21 AEO70684.1 - 1.1e-09 37.7 0.2 3.1e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAT1 PF09770.4 AEO70685.1 - 0.00037 18.9 38.1 0.00041 18.7 26.4 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 AEO70685.1 - 0.002 18.0 22.0 0.0025 17.7 15.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Suf PF05843.9 AEO70685.1 - 0.0047 16.7 14.5 0.0058 16.3 10.1 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) SR-25 PF10500.4 AEO70685.1 - 0.011 15.2 9.6 0.016 14.7 6.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MIP-T3 PF10243.4 AEO70685.1 - 0.015 13.7 18.3 0.019 13.4 12.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF4557 PF15101.1 AEO70685.1 - 0.056 13.2 19.9 0.087 12.6 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4175 PF13779.1 AEO70685.1 - 0.079 10.6 34.2 0.1 10.2 23.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) zf-DHHC PF01529.15 AEO70685.1 - 0.12 11.8 1.6 0.15 11.4 1.1 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Med15 PF09606.5 AEO70685.1 - 0.13 10.4 44.1 0.18 9.9 30.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AvrE PF11725.3 AEO70685.1 - 0.19 8.6 14.8 0.22 8.5 10.3 1.0 1 0 0 1 1 1 0 Pathogenicity factor SRP-alpha_N PF04086.8 AEO70685.1 - 0.28 10.5 15.6 0.41 9.9 10.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Band_3_cyto PF07565.8 AEO70685.1 - 0.29 10.5 9.4 0.39 10.2 6.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Baculo_PP31 PF05311.6 AEO70685.1 - 0.33 10.1 10.1 0.46 9.7 7.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CDC45 PF02724.9 AEO70685.1 - 0.33 8.9 7.6 0.4 8.6 5.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF566 PF04484.7 AEO70685.1 - 0.35 10.3 14.2 0.49 9.8 9.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Neur_chan_memb PF02932.11 AEO70685.1 - 0.47 10.2 8.2 0.62 9.9 5.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 AEO70685.1 - 0.48 8.0 12.4 0.57 7.8 8.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RNA_pol_Rpb1_2 PF00623.15 AEO70685.1 - 0.54 10.2 4.3 0.87 9.5 3.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 Ndc1_Nup PF09531.5 AEO70685.1 - 0.68 8.2 14.2 0.84 7.9 9.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ycf1 PF05758.7 AEO70685.1 - 0.7 7.5 10.5 0.89 7.1 7.3 1.0 1 0 0 1 1 1 0 Ycf1 Plasmodium_Vir PF05795.6 AEO70685.1 - 0.7 9.0 4.6 0.92 8.6 3.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM176 PF14851.1 AEO70685.1 - 0.72 9.5 7.3 1.1 8.8 5.1 1.2 1 0 0 1 1 1 0 FAM176 family Mitofilin PF09731.4 AEO70685.1 - 0.83 8.2 16.7 1.1 7.8 11.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RR_TM4-6 PF06459.7 AEO70685.1 - 0.9 9.3 12.3 1.3 8.9 8.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 AEO70685.1 - 1.1 8.2 7.1 1.5 7.7 4.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter AUX_IAA PF02309.11 AEO70685.1 - 1.1 8.8 10.3 1.6 8.4 7.1 1.2 1 0 0 1 1 1 0 AUX/IAA family CDK5_activator PF03261.10 AEO70685.1 - 1.3 8.3 13.1 1.6 7.9 9.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DDHD PF02862.12 AEO70685.1 - 1.8 8.2 11.2 2.6 7.7 7.8 1.2 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.7 AEO70685.1 - 2 6.9 15.2 2.7 6.4 10.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PIH1 PF08190.7 AEO70685.1 - 2 7.7 21.2 3.1 7.1 14.7 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 FLO_LFY PF01698.11 AEO70685.1 - 2.2 7.0 8.9 3.2 6.5 6.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Tim54 PF11711.3 AEO70685.1 - 2.3 6.7 10.8 3.1 6.2 7.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.1 AEO70685.1 - 2.4 8.3 11.6 3.7 7.7 8.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Serinc PF03348.10 AEO70685.1 - 2.5 6.7 9.2 3.3 6.3 6.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.12 AEO70685.1 - 2.8 6.6 4.3 3.2 6.4 3.0 1.2 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.1 AEO70685.1 - 3 7.5 10.0 4.4 6.9 6.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Herpes_TAF50 PF03326.8 AEO70685.1 - 3.1 6.6 31.7 4 6.2 22.0 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) NARP1 PF12569.3 AEO70685.1 - 3.8 6.1 11.9 5 5.7 8.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4407 PF14362.1 AEO70685.1 - 4.6 6.0 11.9 6.4 5.6 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_U57 PF05582.7 AEO70685.1 - 4.9 6.0 6.3 6.7 5.5 4.4 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Gti1_Pac2 PF09729.4 AEO70685.1 - 6.4 6.6 8.8 7.4 6.4 5.1 1.7 2 0 0 2 2 2 0 Gti1/Pac2 family BRF1 PF07741.8 AEO70685.1 - 7.3 6.8 13.8 13 6.0 9.6 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Peptidase_S49_N PF08496.5 AEO70685.1 - 7.8 6.2 9.4 13 5.5 6.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Nucleo_P87 PF07267.6 AEO70685.1 - 8.1 4.9 14.8 10 4.6 10.3 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NAD_binding_10 PF13460.1 AEO70686.1 - 1.2e-06 28.6 0.0 1.8e-06 28.0 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 AEO70686.1 - 0.0035 17.2 0.0 0.0072 16.2 0.0 1.5 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 AEO70686.1 - 0.006 16.0 0.0 0.013 14.9 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 AEO70686.1 - 0.044 13.7 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_4 PF07993.7 AEO70686.1 - 0.089 11.6 0.0 0.21 10.5 0.0 1.6 1 0 0 1 1 1 0 Male sterility protein NmrA PF05368.8 AEO70686.1 - 0.16 11.1 0.0 0.37 10.0 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family DHDPS PF00701.17 AEO70687.1 - 4e-43 147.0 0.0 5.2e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Chromo PF00385.19 AEO70688.1 - 8.5e-10 38.1 1.7 1.8e-09 37.1 1.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ThiF PF00899.16 AEO70689.1 - 3.1e-39 133.8 0.0 4.8e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 AEO70689.1 - 1.8e-15 56.2 2.4 2.1e-14 52.8 1.6 2.2 1 1 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 AEO70689.1 - 1.6e-11 44.5 0.0 4.9e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.15 AEO70689.1 - 0.00055 20.0 0.2 0.0021 18.1 0.1 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 AEO70689.1 - 0.0053 17.0 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding SLX9 PF15341.1 AEO70690.1 - 7.2e-35 120.0 6.1 7.2e-35 120.0 4.2 2.2 2 1 0 2 2 2 1 Ribosome biogenesis protein SLX9 Adeno_E1B_55K_N PF04623.7 AEO70690.1 - 0.057 13.9 7.8 0.21 12.1 5.4 2.0 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus MSA-2c PF12238.3 AEO70690.1 - 0.96 9.0 4.8 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 Merozoite surface antigen 2c DUF4510 PF14971.1 AEO70690.1 - 7.1 6.7 12.4 0.17 12.0 2.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4510) Peptidase_C48 PF02902.14 AEO70691.1 - 2.1e-15 56.9 0.6 3.3e-14 53.0 0.4 2.3 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AIG2_2 PF13772.1 AEO70693.1 - 2.6e-06 27.4 0.1 6.7e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 AIG2-like family NAD_Gly3P_dh_N PF01210.18 AEO70694.1 - 3.7e-47 159.9 0.1 9.5e-47 158.6 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 AEO70694.1 - 3.1e-37 127.5 0.0 4.7e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus DUF4190 PF13828.1 AEO70694.1 - 4 7.0 6.0 38 3.9 1.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) Sugar_tr PF00083.19 AEO70695.1 - 5.9e-51 173.4 13.2 6.8e-50 169.9 9.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO70695.1 - 2.5e-08 33.0 21.2 2.5e-08 33.0 14.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Amastin PF07344.6 AEO70695.1 - 0.055 13.0 7.8 1.9 8.1 4.2 2.4 1 1 1 2 2 2 0 Amastin surface glycoprotein Mem_trans PF03547.13 AEO70695.1 - 1.5 7.0 8.2 5.5 5.1 5.2 1.9 1 1 1 2 2 2 0 Membrane transport protein RseC_MucC PF04246.7 AEO70695.1 - 6.5 6.3 7.2 1.2 8.6 0.2 2.5 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Prothymosin PF03247.9 AEO70696.1 - 0.037 14.1 9.2 0.048 13.8 6.4 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family CENP-B_dimeris PF09026.5 AEO70696.1 - 0.12 12.5 3.4 0.19 12.0 2.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DTHCT PF08070.6 AEO70696.1 - 0.22 12.2 5.5 0.18 12.5 3.0 1.4 1 1 0 1 1 1 0 DTHCT (NUC029) region Spore_coat_CotO PF14153.1 AEO70696.1 - 0.32 10.3 2.7 0.36 10.2 1.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Nucleoplasmin PF03066.10 AEO70696.1 - 0.48 9.9 5.7 0.54 9.7 4.0 1.1 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 AEO70696.1 - 0.93 9.0 7.0 0.97 9.0 4.8 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 AEO70696.1 - 1.1 9.6 8.8 1.6 9.0 6.1 1.5 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zn_clus PF00172.13 AEO70698.1 - 3.7e-09 36.3 9.2 6e-09 35.6 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 AEO70698.1 - 1.9 8.6 10.0 3.1 8.0 6.9 1.3 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region CHIPS PF11434.3 AEO70699.1 - 0.027 14.0 2.0 0.032 13.8 1.4 1.2 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS Pkinase PF00069.20 AEO70700.1 - 8.7e-17 61.1 0.0 1.2e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO70700.1 - 5e-08 32.3 0.0 7e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO70700.1 - 1.7e-05 24.6 0.0 2.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 AEO70700.1 - 0.00013 21.3 0.0 0.00028 20.2 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 AEO70700.1 - 0.00014 21.0 0.0 0.0002 20.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 AEO70700.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 AEO70700.1 - 0.021 13.7 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Glyco_hydro_71 PF03659.9 AEO70702.1 - 1e-05 24.2 0.0 1.4e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Fungal_trans PF04082.13 AEO70702.1 - 0.0062 15.4 0.1 0.0084 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain RVT_1 PF00078.22 AEO70703.1 - 0.058 12.7 0.1 0.066 12.5 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Bac_rhodopsin PF01036.13 AEO70704.1 - 8.8e-21 74.2 15.8 1e-20 74.0 10.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein MerC PF03203.9 AEO70704.1 - 0.25 11.7 7.7 0.15 12.4 3.8 1.7 1 1 1 2 2 2 0 MerC mercury resistance protein DUF4059 PF13268.1 AEO70704.1 - 7.8 6.7 6.2 1.2 9.4 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) Pyr_redox_3 PF13738.1 AEO70705.1 - 7e-20 71.9 0.0 1.3e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AEO70705.1 - 9.7e-16 57.0 0.0 8e-15 54.0 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 AEO70705.1 - 3.8e-08 33.4 0.0 0.0092 15.8 0.2 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO70705.1 - 1.8e-06 27.0 0.0 4.2e-05 22.6 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 AEO70705.1 - 2.1e-06 27.6 2.0 8e-06 25.7 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO70705.1 - 4.9e-06 25.6 0.1 4.9e-06 25.6 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO70705.1 - 2.3e-05 24.6 4.6 0.0061 16.9 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 AEO70705.1 - 4.1e-05 23.6 0.1 0.0049 16.9 0.0 2.4 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 AEO70705.1 - 0.0047 16.5 0.1 0.0096 15.5 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 AEO70705.1 - 0.017 14.9 4.2 0.21 11.3 0.5 3.0 2 1 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 AEO70705.1 - 0.047 13.9 0.0 0.49 10.6 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 AEO70705.1 - 0.05 12.0 3.3 0.71 8.2 0.4 2.3 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 AEO70705.1 - 0.061 12.1 6.6 0.075 11.8 1.0 2.1 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.16 AEO70705.1 - 0.4 10.2 1.4 4.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 AEO70705.1 - 3.3 6.4 5.4 2.1 7.1 0.5 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A EMP70 PF02990.11 AEO70706.1 - 8.2e-196 651.4 4.8 1e-195 651.1 3.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 PIRT PF15099.1 AEO70706.1 - 0.15 11.2 1.2 0.38 9.9 0.9 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF3406 PF11886.3 AEO70706.1 - 0.18 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3406) Med4 PF10018.4 AEO70708.1 - 1.7e-42 144.9 16.2 3.2e-42 144.0 11.2 1.5 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 ARGLU PF15346.1 AEO70708.1 - 0.0024 17.6 19.0 0.0024 17.6 13.2 2.1 2 0 0 2 2 2 1 Arginine and glutamate-rich 1 MAP7 PF05672.6 AEO70708.1 - 0.0067 15.8 24.8 0.013 14.9 17.2 1.4 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family Nop25 PF09805.4 AEO70708.1 - 0.051 13.6 16.2 0.12 12.5 11.2 1.7 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Caldesmon PF02029.10 AEO70708.1 - 0.062 11.7 20.8 0.096 11.0 14.5 1.2 1 0 0 1 1 1 0 Caldesmon TFIIA PF03153.8 AEO70708.1 - 0.21 11.4 9.0 0.25 11.1 6.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2058 PF09831.4 AEO70708.1 - 0.92 9.3 8.4 2.9 7.7 5.9 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF2098 PF09871.4 AEO70708.1 - 7.9 6.4 8.4 21 5.1 5.8 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) DIE2_ALG10 PF04922.7 AEO70709.1 - 9.9e-77 258.5 13.5 9.8e-70 235.4 4.6 2.4 2 1 0 2 2 2 2 DIE2/ALG10 family PAT1 PF09770.4 AEO70710.1 - 3 5.9 6.9 3.3 5.8 4.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Methyltransf_11 PF08241.7 AEO70712.1 - 2.2e-22 79.3 0.0 4e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO70712.1 - 3.9e-22 78.4 0.0 5.1e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO70712.1 - 9.8e-17 61.5 0.0 2.2e-16 60.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO70712.1 - 3.6e-16 59.3 0.0 8.5e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO70712.1 - 5.5e-16 58.7 0.0 8.5e-16 58.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO70712.1 - 4.5e-15 55.9 0.0 9.1e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO70712.1 - 2e-14 53.6 0.1 3.6e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO70712.1 - 3.1e-13 49.3 0.0 4.7e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 AEO70712.1 - 7e-09 35.2 0.0 1.1e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.11 AEO70712.1 - 2.8e-07 29.2 0.0 3.9e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.12 AEO70712.1 - 2.5e-05 23.4 0.0 0.00011 21.2 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 AEO70712.1 - 4.4e-05 23.1 0.0 5.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.13 AEO70712.1 - 5.5e-05 22.5 0.0 0.01 15.1 0.0 2.3 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain MetW PF07021.7 AEO70712.1 - 0.00018 20.9 0.0 0.00049 19.5 0.0 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 AEO70712.1 - 0.00023 19.9 0.0 0.00035 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 AEO70712.1 - 0.00082 19.0 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 AEO70712.1 - 0.00086 19.3 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 AEO70712.1 - 0.00098 18.2 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FmrO PF07091.6 AEO70712.1 - 0.0021 17.1 0.0 0.0032 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) RrnaAD PF00398.15 AEO70712.1 - 0.0053 15.8 0.0 0.0077 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.7 AEO70712.1 - 0.0057 15.9 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase NodS PF05401.6 AEO70712.1 - 0.0071 15.7 0.0 0.02 14.2 0.0 1.6 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.10 AEO70712.1 - 0.013 15.1 0.0 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase DUF938 PF06080.7 AEO70712.1 - 0.036 13.6 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) UPF0020 PF01170.13 AEO70712.1 - 0.038 13.5 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.8 AEO70712.1 - 0.15 11.1 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ank_2 PF12796.2 AEO70713.1 - 1.3e-28 99.1 0.9 7.4e-14 51.8 0.3 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AEO70713.1 - 1.6e-18 64.9 1.0 0.00025 20.9 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.25 AEO70713.1 - 3.7e-17 61.1 8.0 0.00014 21.4 0.0 6.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 AEO70713.1 - 1.2e-16 60.2 1.3 4.3e-07 29.9 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO70713.1 - 3.4e-15 56.0 0.1 1e-08 35.4 0.0 3.8 1 1 0 3 3 3 2 Ankyrin repeats (many copies) NACHT PF05729.7 AEO70713.1 - 3.2e-09 36.6 0.0 6.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 AEO70713.1 - 8.4e-07 29.1 1.4 1.6e-06 28.2 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AEO70713.1 - 3.3e-06 27.2 0.0 1.1e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 AEO70713.1 - 0.0038 17.4 0.0 0.021 15.0 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 AEO70713.1 - 0.091 11.7 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ank_2 PF12796.2 AEO70714.1 - 2.4e-63 210.4 26.7 2.6e-09 37.2 0.0 14.5 9 4 4 14 14 14 12 Ankyrin repeats (3 copies) Ank PF00023.25 AEO70714.1 - 1.8e-26 90.5 45.2 0.00015 21.3 0.0 20.9 20 2 1 21 21 21 10 Ankyrin repeat Ank_4 PF13637.1 AEO70714.1 - 3.4e-25 87.9 11.9 8.6e-05 22.9 0.0 14.5 15 3 2 17 17 17 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO70714.1 - 8.8e-22 75.0 15.8 0.033 14.4 0.0 18.4 19 1 0 19 19 19 4 Ankyrin repeat Ank_5 PF13857.1 AEO70714.1 - 8e-16 57.7 34.6 2.8e-06 27.3 0.0 15.1 14 2 2 16 16 16 3 Ankyrin repeats (many copies) Amidase PF01425.16 AEO70715.1 - 3.4e-90 303.0 0.0 4.1e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 Amidase ADH_zinc_N PF00107.21 AEO70716.1 - 3.1e-27 94.6 0.8 4.9e-27 94.0 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO70716.1 - 4.3e-18 66.4 1.5 9.9e-18 65.2 0.4 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO70716.1 - 6.5e-11 41.9 0.1 7.5e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 AEO70717.1 - 5.6e-45 153.6 0.0 7.8e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 AEO70717.1 - 5.1e-25 87.1 0.0 9.1e-25 86.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 AEO70717.1 - 9.9e-15 53.9 0.0 2e-14 52.9 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 AEO70717.1 - 2.3e-14 53.0 0.0 3.9e-12 45.6 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 AEO70717.1 - 7.5e-14 51.2 0.0 1.2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 AEO70717.1 - 9.7e-13 48.3 0.0 1.5e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 AEO70717.1 - 3.6e-09 35.9 0.0 3.1e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 AEO70717.1 - 5.8e-09 36.1 0.0 1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 AEO70717.1 - 9.7e-09 35.1 0.0 1.9e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 AEO70717.1 - 0.0085 15.1 0.1 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 AEO70717.1 - 0.0086 15.3 0.0 0.046 12.9 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 AEO70717.1 - 0.012 14.9 0.2 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 AEO70717.1 - 0.024 15.2 0.0 2.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain DAO PF01266.19 AEO70717.1 - 0.1 11.4 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Sad1_UNC PF07738.8 AEO70719.1 - 5e-11 42.5 0.0 0.00039 20.2 0.0 3.1 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal SGT1 PF07093.6 AEO70719.1 - 0.0051 15.2 1.4 0.0071 14.7 1.0 1.1 1 0 0 1 1 1 1 SGT1 protein GPP34 PF05719.6 AEO70719.1 - 0.16 12.0 4.9 0.46 10.5 0.2 3.1 3 1 0 3 3 3 0 Golgi phosphoprotein 3 (GPP34) Prefoldin_2 PF01920.15 AEO70719.1 - 0.17 11.6 5.4 0.26 11.0 0.1 3.2 4 0 0 4 4 4 0 Prefoldin subunit Fib_alpha PF08702.5 AEO70719.1 - 2.8 8.0 5.6 8.2 6.5 0.7 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DEAD PF00270.24 AEO70720.1 - 2.3e-43 147.5 0.0 5.1e-43 146.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 AEO70720.1 - 7.9e-25 86.1 0.1 1.8e-24 85.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 AEO70720.1 - 7.7e-22 76.9 0.0 1.5e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO70720.1 - 0.046 13.5 0.0 0.046 13.5 0.0 2.9 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit Pectinesterase PF01095.14 AEO70721.1 - 5.9e-25 87.4 0.0 1.6e-21 76.1 0.0 2.1 2 0 0 2 2 2 2 Pectinesterase Transp_cyt_pur PF02133.10 AEO70722.1 - 9.4e-152 505.5 35.9 1.1e-151 505.3 24.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SNF2_N PF00176.18 AEO70725.1 - 2.1e-47 161.3 0.0 3.1e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO70725.1 - 1.8e-11 43.6 0.0 4e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2255 PF10012.4 AEO70725.1 - 0.11 12.5 0.4 0.52 10.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2255) MFS_1 PF07690.11 AEO70726.1 - 2.3e-29 102.2 50.4 2.3e-29 102.2 34.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily PQQ PF01011.16 AEO70727.1 - 2.6e-12 45.6 7.3 0.093 12.2 0.0 6.6 6 0 0 6 6 6 4 PQQ enzyme repeat PQQ_2 PF13360.1 AEO70727.1 - 3.8e-10 39.6 11.0 0.0033 16.9 0.2 5.1 1 1 3 4 4 4 4 PQQ-like domain PQQ_3 PF13570.1 AEO70727.1 - 2.3e-08 34.0 27.0 0.0018 18.4 2.4 7.3 8 1 0 8 8 8 4 PQQ-like domain SNF2_N PF00176.18 AEO70728.1 - 1.4e-39 135.7 0.0 5.2e-39 133.8 0.0 2.0 2 1 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 AEO70728.1 - 1e-08 34.7 5.8 1.8e-08 33.9 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO70728.1 - 5e-08 32.8 9.4 1e-07 31.8 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO70728.1 - 1.1e-07 31.3 9.5 2e-07 30.5 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO70728.1 - 3.6e-07 29.7 7.4 6.4e-07 28.9 5.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.26 AEO70728.1 - 7.3e-07 28.9 0.0 1.7e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 AEO70728.1 - 1.4e-06 27.9 8.4 2.7e-06 27.1 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AEO70728.1 - 0.0002 21.3 2.2 0.0005 20.1 1.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger DUF2255 PF10012.4 AEO70728.1 - 0.016 15.1 0.1 0.035 14.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) zf-RING_UBOX PF13445.1 AEO70728.1 - 0.023 14.3 1.9 0.057 13.1 1.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AEO70728.1 - 0.037 13.9 9.8 0.08 12.8 6.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING HTH_AsnC-type PF13404.1 AEO70728.1 - 0.054 13.0 0.0 0.26 10.8 0.0 2.2 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain zf-RING_4 PF14570.1 AEO70728.1 - 0.23 11.0 8.3 0.58 9.7 5.8 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Phage_B PF02304.10 AEO70729.1 - 0.0099 16.1 2.6 0.013 15.7 1.2 1.6 1 1 0 1 1 1 1 Scaffold protein B V-SNARE PF05008.10 AEO70729.1 - 0.024 14.8 4.4 0.53 10.4 0.1 2.4 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus GCN5L1 PF06320.8 AEO70729.1 - 0.041 13.7 4.9 0.06 13.1 3.4 1.2 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Sec8_exocyst PF04048.9 AEO70729.1 - 0.058 13.0 0.7 0.1 12.2 0.5 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain TMF_DNA_bd PF12329.3 AEO70729.1 - 0.059 13.1 4.2 0.64 9.8 0.4 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 AEO70729.1 - 0.061 13.1 5.4 0.082 12.7 3.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) MTBP_C PF14920.1 AEO70729.1 - 0.074 12.5 4.8 0.095 12.1 3.3 1.1 1 0 0 1 1 1 0 MDM2-binding CAF-1_p150 PF11600.3 AEO70729.1 - 0.077 12.3 5.5 0.1 11.9 3.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Prefoldin_2 PF01920.15 AEO70729.1 - 0.1 12.3 5.1 0.64 9.7 3.6 1.9 1 1 0 1 1 1 0 Prefoldin subunit LMP PF04778.7 AEO70729.1 - 0.13 11.9 0.8 0.18 11.5 0.5 1.2 1 0 0 1 1 1 0 LMP repeated region Atg14 PF10186.4 AEO70729.1 - 0.22 10.4 3.8 0.26 10.2 2.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3584 PF12128.3 AEO70729.1 - 0.24 8.7 6.3 0.26 8.5 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4200 PF13863.1 AEO70729.1 - 0.37 10.7 9.5 0.55 10.1 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4404 PF14357.1 AEO70729.1 - 0.56 10.6 8.6 0.58 10.6 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) APG6 PF04111.7 AEO70729.1 - 0.76 8.7 6.0 0.94 8.4 4.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Lge1 PF11488.3 AEO70729.1 - 1.1 9.4 4.0 0.91 9.7 0.3 2.1 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 WXG100 PF06013.7 AEO70729.1 - 1.4 8.9 6.2 4.3 7.4 0.3 2.6 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Mnd1 PF03962.10 AEO70729.1 - 2.5 7.6 5.6 3.6 7.2 3.9 1.2 1 0 0 1 1 1 0 Mnd1 family DUF4140 PF13600.1 AEO70729.1 - 3 8.3 11.3 0.53 10.7 1.4 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) OEP PF02321.13 AEO70729.1 - 6.9 6.2 9.4 0.87 9.1 0.8 2.1 1 1 1 2 2 2 0 Outer membrane efflux protein FUSC PF04632.7 AEO70729.1 - 7.8 4.7 13.0 9.7 4.4 9.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Acetyltransf_1 PF00583.19 AEO70730.1 - 2.5e-09 37.0 0.1 3.3e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO70730.1 - 4.3e-08 33.1 0.0 1e-07 32.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO70730.1 - 7.6e-08 32.4 0.0 3.1e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO70730.1 - 1.4e-06 27.9 0.0 2.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 AEO70730.1 - 0.00017 21.4 0.0 0.00043 20.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AEO70730.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase OPT PF03169.10 AEO70731.1 - 5.7e-124 414.8 42.4 6.6e-124 414.6 29.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1980 PF09323.5 AEO70731.1 - 4.1 7.1 6.8 0.22 11.2 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Na_H_Exchanger PF00999.16 AEO70732.1 - 5e-26 91.1 49.4 7.8e-16 57.5 16.4 2.4 2 1 0 2 2 2 2 Sodium/hydrogen exchanger family Fst_toxin PF13955.1 AEO70732.1 - 0.041 13.5 1.0 0.041 13.5 0.7 4.6 6 0 0 6 6 6 0 Toxin Fst, type I toxin-antitoxin system HLH PF00010.21 AEO70734.1 - 3.3e-08 33.0 0.1 1.1e-07 31.4 0.1 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Herpes_UL6 PF01763.11 AEO70734.1 - 0.085 11.0 0.0 0.13 10.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Sulfate_transp PF00916.15 AEO70735.1 - 1.1e-82 277.1 10.6 1.7e-82 276.6 7.4 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 AEO70735.1 - 1.9e-29 101.1 3.3 1.9e-29 101.1 2.3 2.8 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif DUF1700 PF08006.6 AEO70735.1 - 6.4 6.0 8.7 9.1 5.5 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) AAA PF00004.24 AEO70736.1 - 1.9e-11 44.2 0.0 3.7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO70736.1 - 1.3e-06 28.5 0.0 4.2e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AEO70736.1 - 4.4e-05 22.6 0.0 8.5e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AEO70736.1 - 6.3e-05 22.6 0.7 0.00071 19.2 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 AEO70736.1 - 0.00029 20.7 0.0 0.00092 19.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO70736.1 - 0.00061 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AEO70736.1 - 0.0027 17.7 0.3 0.057 13.3 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 AEO70736.1 - 0.0036 17.1 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO70736.1 - 0.0041 17.9 0.0 0.015 16.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.10 AEO70736.1 - 0.006 15.3 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 AEO70736.1 - 0.014 14.4 0.2 0.039 13.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.17 AEO70736.1 - 0.015 14.1 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 AEO70736.1 - 0.023 13.8 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DNA_pol3_delta PF06144.8 AEO70736.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit IstB_IS21 PF01695.12 AEO70736.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein eIF3g PF12353.3 AEO70737.1 - 0.088 12.7 0.3 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G DUF1772 PF08592.6 AEO70738.1 - 2.1e-11 43.7 10.0 1.2e-08 34.8 0.6 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) CsoSCA PF08936.5 AEO70738.1 - 0.077 11.3 0.1 0.088 11.1 0.1 1.0 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase MARVEL PF01284.18 AEO70739.1 - 0.00042 20.1 14.4 0.0069 16.2 10.5 2.0 2 0 0 2 2 2 1 Membrane-associating domain Shisa PF13908.1 AEO70739.1 - 3.1 7.9 7.8 1.2 9.3 3.5 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Amidohydro_1 PF01979.15 AEO70740.1 - 8.5e-39 134.1 0.0 1.1e-38 133.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 AEO70740.1 - 1.2e-05 25.0 0.0 4.4e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 AEO70740.1 - 0.0021 17.3 13.9 0.0097 15.1 5.3 2.5 1 1 0 2 2 2 2 Amidohydrolase family KaiC PF06745.8 AEO70740.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 KaiC ketoacyl-synt PF00109.21 AEO70741.1 - 3.3e-21 75.9 0.8 5.4e-21 75.2 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 AEO70741.1 - 3.1e-16 59.8 0.0 6.9e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 AEO70741.1 - 1.3e-10 41.1 0.0 2.6e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 AEO70741.1 - 0.00033 20.6 0.0 0.0014 18.5 0.0 2.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO70741.1 - 0.023 14.3 0.0 0.11 12.1 0.0 2.1 1 0 0 1 1 1 0 KR domain Acyl_transf_1 PF00698.16 AEO70742.1 - 1.9e-79 267.3 0.0 8e-78 261.9 0.0 3.3 4 0 0 4 4 4 1 Acyl transferase domain MaoC_dehydratas PF01575.14 AEO70742.1 - 5.5e-38 129.1 0.1 1.3e-37 127.9 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 AEO70742.1 - 1.1e-31 108.3 0.5 7.3e-31 105.7 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 AEO70742.1 - 1e-22 80.3 0.2 4.2e-22 78.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 AEO70742.1 - 0.0011 18.1 0.1 0.25 10.4 0.0 2.6 3 0 0 3 3 3 2 Nitronate monooxygenase SH3_1 PF00018.23 AEO70744.1 - 2.6e-11 42.7 0.2 8.3e-11 41.1 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 AEO70744.1 - 2.5e-09 36.5 0.0 2.2e-08 33.5 0.1 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 AEO70744.1 - 9.1e-09 34.6 0.0 3.8e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain RPAP2_Rtr1 PF04181.8 AEO70745.1 - 2.5e-15 56.3 0.0 5.2e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family AAA_16 PF13191.1 AEO70745.1 - 0.065 13.2 0.5 0.16 11.9 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain Ribosomal_S17e PF00833.13 AEO70746.1 - 2.1e-58 195.3 0.1 2.5e-58 195.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 AEO70746.1 - 0.095 13.4 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Mit_ribos_Mrp51 PF11709.3 AEO70747.1 - 1.2e-96 323.5 0.0 1.5e-96 323.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit TGT PF01702.13 AEO70748.1 - 5e-86 287.8 0.0 6.1e-86 287.5 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Pkinase PF00069.20 AEO70750.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Hist_deacetyl PF00850.14 AEO70752.1 - 6.8e-64 216.1 0.1 1e-63 215.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF940 PF06082.6 AEO70752.1 - 0.64 8.5 2.8 0.99 7.8 1.9 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Abhydrolase_6 PF12697.2 AEO70753.1 - 2.3e-29 102.9 2.5 1e-28 100.7 1.7 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO70753.1 - 6.3e-18 65.1 0.1 3.8e-16 59.3 0.0 3.1 2 2 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO70753.1 - 5.5e-12 45.6 0.0 1.3e-10 41.1 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 AEO70753.1 - 8.5e-07 28.3 0.0 1.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 AEO70753.1 - 3.7e-05 23.2 0.0 7.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 AEO70753.1 - 0.0012 19.1 0.0 0.0044 17.2 0.0 2.0 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.11 AEO70753.1 - 0.0029 17.0 0.0 2.7 7.3 0.0 2.7 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 AEO70753.1 - 0.026 14.1 0.2 0.095 12.2 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 AEO70753.1 - 0.03 13.9 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.3 AEO70753.1 - 0.032 14.0 0.0 0.082 12.7 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase PGAP1 PF07819.8 AEO70753.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.2 AEO70753.1 - 0.078 11.8 0.0 0.16 10.8 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF2305 PF10230.4 AEO70753.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Spo7 PF03907.8 AEO70754.1 - 3.7e-69 232.4 0.1 5e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein DSPc PF00782.15 AEO70755.1 - 3.6e-11 42.7 0.0 1.5e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AEO70755.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF3313 PF11769.3 AEO70755.1 - 0.091 12.1 1.3 0.35 10.2 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3313) Abhydrolase_1 PF00561.15 AEO70756.1 - 2.2e-44 151.7 0.0 3e-23 82.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AEO70756.1 - 2.3e-13 50.5 2.1 2.5e-12 47.1 1.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO70756.1 - 0.0024 17.6 0.1 0.033 13.9 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 AEO70756.1 - 0.039 13.8 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Tho2 PF11262.3 AEO70757.1 - 8.2e-89 297.5 0.4 1.2e-88 297.0 0.3 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 AEO70757.1 - 7.4e-28 96.1 0.1 1.6e-27 95.0 0.1 1.6 1 0 0 1 1 1 1 Transcription- and export-related complex subunit PAE PF03283.8 AEO70757.1 - 2.2 6.8 0.0 3.4 6.1 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase WSC PF01822.14 AEO70758.1 - 4.7e-13 48.8 6.0 4.7e-13 48.8 4.2 1.9 2 0 0 2 2 2 1 WSC domain Podoplanin PF05808.6 AEO70758.1 - 0.00019 21.0 5.9 0.00029 20.4 4.1 1.2 1 0 0 1 1 1 1 Podoplanin Adeno_E3_CR2 PF02439.10 AEO70758.1 - 0.0012 18.3 0.0 0.0027 17.1 0.0 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Mid2 PF04478.7 AEO70758.1 - 0.0035 16.7 0.5 0.006 16.0 0.4 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Glycophorin_A PF01102.13 AEO70758.1 - 0.01 15.5 0.9 0.019 14.7 0.6 1.5 1 0 0 1 1 1 0 Glycophorin A SKG6 PF08693.5 AEO70758.1 - 2.4 7.5 7.3 0.13 11.5 0.7 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain SKG6 PF08693.5 AEO70759.1 - 0.0001 21.5 0.0 0.00024 20.3 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4381 PF14316.1 AEO70759.1 - 0.014 15.5 0.1 0.031 14.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) GAPT PF11770.3 AEO70759.1 - 0.21 11.2 0.0 0.43 10.2 0.0 1.4 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) DUF221 PF02714.10 AEO70761.1 - 6.7e-107 357.0 21.9 6.7e-107 357.0 15.2 2.4 4 0 0 4 4 4 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AEO70761.1 - 9e-44 148.7 1.2 9e-44 148.7 0.8 2.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 AEO70761.1 - 9.6e-31 105.5 0.0 2.1e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 AEO70761.1 - 2.4e-24 85.6 0.4 3.9e-24 84.9 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) MFS_1 PF07690.11 AEO70762.1 - 3.1e-39 134.7 47.4 5.3e-39 133.9 32.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4006 PF13179.1 AEO70762.1 - 0.78 9.3 3.9 0.61 9.6 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF4006) ATP-synt_8 PF00895.15 AEO70763.1 - 0.011 15.9 0.1 0.014 15.5 0.1 1.2 1 0 0 1 1 1 0 ATP synthase protein 8 Amnionless PF14828.1 AEO70763.1 - 0.13 10.6 0.1 0.15 10.5 0.1 1.0 1 0 0 1 1 1 0 Amnionless DUF4131 PF13567.1 AEO70763.1 - 0.27 10.6 4.4 0.27 10.6 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3317 PF11779.3 AEO70763.1 - 0.29 10.6 2.2 0.42 10.0 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) Fungal_trans PF04082.13 AEO70764.1 - 3.3e-17 62.2 0.0 6.9e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO70764.1 - 1.5e-09 37.5 8.9 2.8e-09 36.7 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hid1 PF12722.2 AEO70764.1 - 0.24 9.0 1.8 0.32 8.6 1.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4557 PF15101.1 AEO70764.1 - 0.5 10.1 12.8 0.83 9.4 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) RIC3 PF15361.1 AEO70764.1 - 1.4 9.1 9.4 3.2 7.9 6.5 1.6 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 PAT1 PF09770.4 AEO70764.1 - 1.8 6.7 30.7 2.5 6.2 21.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 AEO70764.1 - 2.1 8.0 10.1 3.5 7.2 7.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 AEO70764.1 - 3.9 6.7 29.6 6.6 6.0 20.5 1.3 1 0 0 1 1 1 0 Vta1 like Senescence PF06911.7 AEO70765.1 - 3.6e-47 160.3 1.9 5.8e-47 159.6 1.3 1.3 1 0 0 1 1 1 1 Senescence-associated protein Spc97_Spc98 PF04130.8 AEO70766.1 - 6.9e-71 239.1 0.0 8.2e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF4200 PF13863.1 AEO70767.1 - 0.0017 18.2 7.9 0.0031 17.4 5.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Not3 PF04065.10 AEO70767.1 - 0.0027 17.0 2.6 0.0035 16.6 1.8 1.1 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Spc7 PF08317.6 AEO70767.1 - 0.0059 15.3 2.9 0.0088 14.7 2.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Apolipoprotein PF01442.13 AEO70767.1 - 0.0076 15.7 0.6 0.0098 15.4 0.4 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Prefoldin_2 PF01920.15 AEO70767.1 - 0.02 14.6 4.5 0.039 13.7 3.1 1.4 1 0 0 1 1 1 0 Prefoldin subunit DUF262 PF03235.9 AEO70767.1 - 0.03 14.2 1.2 0.035 14.0 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Angiomotin_C PF12240.3 AEO70767.1 - 0.03 13.8 2.1 0.044 13.2 1.5 1.2 1 0 0 1 1 1 0 Angiomotin C terminal DUF1319 PF07028.6 AEO70767.1 - 0.042 14.0 3.4 0.055 13.6 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) TPD52 PF04201.10 AEO70767.1 - 0.044 13.4 1.0 0.066 12.9 0.7 1.4 1 0 0 1 1 1 0 Tumour protein D52 family RelA_SpoT PF04607.12 AEO70767.1 - 0.052 13.5 0.2 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Region found in RelA / SpoT proteins COG2 PF06148.6 AEO70767.1 - 0.061 13.2 1.1 0.14 12.0 0.7 1.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Seryl_tRNA_N PF02403.17 AEO70767.1 - 0.081 12.9 3.6 0.098 12.6 1.7 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PIN_4 PF13638.1 AEO70767.1 - 0.084 12.9 1.0 0.17 11.9 0.7 1.5 1 0 0 1 1 1 0 PIN domain Ran-binding PF05508.6 AEO70767.1 - 0.099 11.5 1.0 0.14 11.0 0.7 1.2 1 0 0 1 1 1 0 RanGTP-binding protein IncA PF04156.9 AEO70767.1 - 0.1 12.1 1.5 0.11 12.0 1.1 1.3 1 0 0 1 1 1 0 IncA protein DUF883 PF05957.8 AEO70767.1 - 0.12 12.7 0.9 0.23 11.9 0.6 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Med21 PF11221.3 AEO70767.1 - 0.15 12.0 7.5 1.9 8.4 0.1 2.1 1 1 1 2 2 2 0 Subunit 21 of Mediator complex Fib_alpha PF08702.5 AEO70767.1 - 0.22 11.6 2.6 0.27 11.3 1.3 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ATG16 PF08614.6 AEO70767.1 - 0.35 10.6 6.3 0.42 10.4 4.0 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TBPIP PF07106.8 AEO70767.1 - 0.5 9.8 5.9 0.65 9.5 3.5 1.6 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Med9 PF07544.8 AEO70767.1 - 0.74 9.5 10.5 0.65 9.7 5.4 2.2 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF4404 PF14357.1 AEO70767.1 - 1.2 9.6 6.0 37 4.8 2.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) DHC_N1 PF08385.7 AEO70768.1 - 8.4e-195 648.4 1.5 8.4e-195 648.4 1.1 4.6 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 AEO70768.1 - 3.7e-130 434.1 6.3 3.7e-130 434.1 4.4 5.3 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 AEO70768.1 - 2.5e-103 346.4 1.8 3e-103 346.2 0.0 2.0 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 AEO70768.1 - 1.2e-77 260.5 0.0 3e-77 259.2 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 AEO70768.1 - 1.3e-42 145.1 0.1 4.3e-42 143.5 0.0 1.9 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 AEO70768.1 - 4.4e-41 140.6 0.4 7.5e-40 136.5 0.1 2.7 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 AEO70768.1 - 3.5e-40 137.8 11.2 3.5e-40 137.8 7.8 2.4 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 AEO70768.1 - 1.7e-31 108.8 0.0 5.1e-12 45.6 0.0 6.2 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 AEO70768.1 - 3.9e-21 75.3 0.0 6.4e-20 71.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 AEO70768.1 - 3.3e-15 56.3 2.3 0.015 15.3 0.0 6.6 7 0 0 7 7 4 3 AAA domain AAA PF00004.24 AEO70768.1 - 2.4e-13 50.4 0.0 0.0019 18.3 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AEO70768.1 - 1.5e-10 41.9 0.1 0.031 15.1 0.0 6.0 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.1 AEO70768.1 - 1.2e-09 38.1 1.5 0.36 10.6 0.0 5.6 5 0 0 5 5 4 3 AAA domain AAA_18 PF13238.1 AEO70768.1 - 5.1e-08 33.2 3.5 0.024 14.9 0.0 5.5 6 0 0 6 6 5 2 AAA domain AAA_14 PF13173.1 AEO70768.1 - 1.8e-07 31.1 0.1 0.21 11.4 0.0 6.2 6 0 0 6 6 5 1 AAA domain T2SE PF00437.15 AEO70768.1 - 3.7e-07 29.3 0.0 0.018 13.9 0.0 4.0 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_16 PF13191.1 AEO70768.1 - 8.5e-07 29.1 28.7 0.083 12.8 0.0 10.0 8 2 3 11 11 11 2 AAA ATPase domain AAA_29 PF13555.1 AEO70768.1 - 1.4e-06 27.7 0.0 0.2 11.1 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_19 PF13245.1 AEO70768.1 - 1.1e-05 25.0 0.1 0.89 9.3 0.0 5.0 5 0 0 5 5 5 1 Part of AAA domain Mg_chelatase PF01078.16 AEO70768.1 - 5.4e-05 22.4 0.6 0.5 9.4 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 AEO70768.1 - 0.00023 21.4 0.1 3.9 7.7 0.0 4.5 3 0 0 3 3 3 1 ABC transporter Zeta_toxin PF06414.7 AEO70768.1 - 0.0013 17.8 3.7 0.97 8.4 0.0 4.4 4 0 0 4 4 3 2 Zeta toxin RNA_helicase PF00910.17 AEO70768.1 - 0.01 15.9 0.1 37 4.5 0.0 4.6 4 0 0 4 4 4 0 RNA helicase MobB PF03205.9 AEO70768.1 - 0.033 13.8 0.1 12 5.5 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 AEO70768.1 - 0.099 12.0 5.0 0.31 10.4 0.0 3.7 4 0 0 4 4 3 0 AAA domain BRE1 PF08647.6 AEO70768.1 - 2.1 8.3 25.6 0.0047 16.8 3.3 3.8 2 0 0 2 2 1 0 BRE1 E3 ubiquitin ligase ERM PF00769.14 AEO70768.1 - 3.7 6.9 32.0 8.9 5.7 3.7 3.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family PHP PF02811.14 AEO70769.1 - 5.7e-10 39.2 0.0 8.4e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 PHP domain DSBA PF01323.15 AEO70769.1 - 0.13 11.8 0.2 0.41 10.1 0.1 1.8 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Ribosomal_60s PF00428.14 AEO70769.1 - 2.8 8.4 8.7 0.058 13.7 1.3 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein ACPS PF01648.15 AEO70770.1 - 1e-05 25.3 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily RVT_1 PF00078.22 AEO70771.1 - 0.02 14.2 0.4 0.02 14.2 0.3 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Exonuc_V_gamma PF04257.9 AEO70771.1 - 0.15 10.0 0.4 0.15 9.9 0.3 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit RVT_1 PF00078.22 AEO70772.1 - 0.025 13.9 0.5 0.025 13.9 0.3 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Clr5 PF14420.1 AEO70774.1 - 2.1e-05 24.2 0.0 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Clr5 domain Fungal_trans PF04082.13 AEO70777.1 - 5.5e-30 104.1 0.0 1.2e-29 102.9 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO70777.1 - 1.1e-08 34.7 8.6 1.9e-08 34.0 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO70777.1 - 0.056 12.0 0.1 0.13 10.7 0.0 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain DUF4306 PF14154.1 AEO70777.1 - 0.15 12.0 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Cyclin_N PF00134.18 AEO70778.1 - 0.064 12.8 0.0 0.25 10.8 0.0 2.0 2 1 0 2 2 2 0 Cyclin, N-terminal domain Dynamin_N PF00350.18 AEO70779.1 - 3.6e-16 59.4 0.1 6.3e-15 55.3 0.0 2.9 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 AEO70779.1 - 0.00048 20.0 0.1 0.012 15.5 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 AEO70779.1 - 0.0042 17.3 0.2 0.024 14.9 0.0 2.5 3 0 0 3 3 2 1 ABC transporter Miro PF08477.8 AEO70779.1 - 0.0071 16.8 0.0 0.028 14.9 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 AEO70779.1 - 0.016 16.0 0.7 0.096 13.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain Adeno_IVa2 PF02456.10 AEO70779.1 - 0.026 13.2 0.0 0.047 12.3 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF258 PF03193.11 AEO70779.1 - 0.062 12.4 0.0 0.4 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 AEO70779.1 - 0.069 13.2 0.6 1.1 9.4 0.0 3.3 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.1 AEO70779.1 - 0.09 12.7 0.0 0.09 12.7 0.0 4.3 6 0 0 6 6 6 0 AAA ATPase domain IncA PF04156.9 AEO70779.1 - 0.097 12.2 21.2 0.078 12.5 0.2 4.3 4 0 0 4 4 4 0 IncA protein DUF1319 PF07028.6 AEO70779.1 - 0.58 10.3 6.1 3.9 7.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1319) Prefoldin_2 PF01920.15 AEO70779.1 - 5.5 6.8 11.6 1.1 9.0 2.4 3.6 3 0 0 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.5 AEO70779.1 - 7 6.7 13.7 2.9 7.9 0.0 4.9 6 0 0 6 6 6 0 Fibrinogen alpha/beta chain family TPR_2 PF07719.12 AEO70780.1 - 6e-10 38.2 4.1 0.027 14.3 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 AEO70780.1 - 8.7e-10 37.7 2.3 0.018 14.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 AEO70780.1 - 1.9e-09 37.0 12.1 0.0006 19.4 0.1 3.6 2 1 2 4 4 4 4 TPR repeat TPR_16 PF13432.1 AEO70780.1 - 5.8e-05 23.6 1.4 5.8e-05 23.6 1.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AEO70780.1 - 0.0022 17.8 0.5 0.27 11.1 0.0 2.7 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 AEO70780.1 - 0.0041 17.4 0.2 0.0041 17.4 0.1 2.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 AEO70780.1 - 0.12 12.6 0.4 1.6 9.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO70780.1 - 0.18 12.5 0.3 0.18 12.5 0.2 4.3 3 2 1 4 4 4 0 Tetratricopeptide repeat DNA_topoisoIV PF00521.15 AEO70781.1 - 1.4e-124 416.1 0.1 2.6e-124 415.3 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 AEO70781.1 - 1.4e-32 112.3 1.3 3.3e-32 111.0 0.9 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 AEO70781.1 - 2.8e-12 46.4 0.2 1.7e-11 43.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 AEO70781.1 - 1.1e-09 38.0 0.0 2.9e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reticulon PF02453.12 AEO70782.1 - 2.4e-39 134.6 4.2 3.3e-39 134.2 2.9 1.2 1 0 0 1 1 1 1 Reticulon RabGAP-TBC PF00566.13 AEO70783.1 - 5.8e-48 163.1 0.3 1.7e-47 161.6 0.0 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain IncA PF04156.9 AEO70783.1 - 0.001 18.7 25.5 0.02 14.5 5.7 3.5 3 0 0 3 3 3 2 IncA protein ADIP PF11559.3 AEO70783.1 - 0.0066 16.3 10.6 0.0066 16.3 7.3 4.0 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding Myosin_tail_1 PF01576.14 AEO70783.1 - 0.017 12.8 31.6 0.0095 13.7 17.7 2.7 2 1 0 2 2 2 0 Myosin tail DUF1664 PF07889.7 AEO70783.1 - 0.11 12.3 6.0 0.042 13.6 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 AEO70783.1 - 0.27 11.1 24.0 0.023 14.5 6.0 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 AEO70783.1 - 0.31 10.7 10.3 0.021 14.5 1.6 2.8 3 0 0 3 3 3 0 Laminin Domain II Prominin PF05478.6 AEO70783.1 - 3.6 4.9 11.5 1.2 6.5 5.0 2.1 1 1 1 2 2 2 0 Prominin TBPIP PF07106.8 AEO70783.1 - 4 6.9 14.6 0.29 10.6 3.0 3.2 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Snapin_Pallidin PF14712.1 AEO70783.1 - 6 7.2 19.3 2 8.7 4.2 3.2 3 0 0 3 3 3 0 Snapin/Pallidin DUF4071 PF13281.1 AEO70783.1 - 6.3 5.5 10.3 7.8 5.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4071) Lipase_GDSL PF00657.17 AEO70785.1 - 1.3e-12 48.0 0.1 1.7e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 AEO70785.1 - 2.3e-05 24.6 6.3 0.00017 21.8 4.4 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Aminotran_1_2 PF00155.16 AEO70786.1 - 1.8e-59 201.5 0.0 2.1e-59 201.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_76 PF03663.9 AEO70787.1 - 1e-131 439.7 1.6 1.3e-131 439.3 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF1680 PF07944.7 AEO70787.1 - 0.092 10.9 0.2 0.19 9.9 0.0 1.5 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) zf-BED PF02892.10 AEO70789.1 - 0.0001 22.0 1.5 0.00019 21.0 1.0 1.5 1 0 0 1 1 1 1 BED zinc finger MscL PF01741.13 AEO70789.1 - 0.021 14.9 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL C1_1 PF00130.17 AEO70789.1 - 0.075 12.7 1.1 0.075 12.7 0.8 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF898 PF05987.8 AEO70790.1 - 0.62 8.8 11.1 0.091 11.6 5.1 1.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) NMO PF03060.10 AEO70792.1 - 2.4e-72 243.8 0.3 3.4e-72 243.3 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 AEO70792.1 - 2.4e-10 39.8 0.2 5.1e-10 38.7 0.1 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 AEO70792.1 - 2.1e-08 33.4 1.1 3.2e-08 32.8 0.7 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 AEO70792.1 - 0.0017 17.3 0.3 0.0029 16.6 0.2 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 AEO70792.1 - 0.0025 16.8 0.1 0.0047 15.8 0.1 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NanE PF04131.9 AEO70792.1 - 0.01 14.8 0.1 0.026 13.5 0.1 1.7 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Pterin_bind PF00809.17 AEO70793.1 - 4.8e-63 212.3 0.0 9.8e-63 211.3 0.0 1.5 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 AEO70793.1 - 2.1e-39 134.1 0.0 3.4e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NDT80_PhoG PF05224.7 AEO70795.1 - 2.8e-46 157.8 0.0 4.3e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family rve PF00665.21 AEO70796.1 - 0.049 13.7 0.0 0.073 13.1 0.0 1.4 1 1 0 1 1 1 0 Integrase core domain RVT_1 PF00078.22 AEO70797.1 - 0.0078 15.5 0.2 0.01 15.2 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ArfGap PF01412.13 AEO70798.1 - 3e-36 123.7 0.8 5.6e-36 122.8 0.1 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf TIM21 PF08294.6 AEO70799.1 - 1.6e-42 144.5 0.1 2.3e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 AEO70799.1 - 1.7e-07 30.7 0.0 3e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 BTB PF00651.26 AEO70800.1 - 0.00089 19.2 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PRKCSH PF07915.8 AEO70801.1 - 0.024 15.4 0.0 0.036 14.8 0.0 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein zf-H2C2_2 PF13465.1 AEO70804.1 - 1e-07 31.8 21.1 2.3e-06 27.6 2.0 3.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 AEO70804.1 - 1.9e-07 30.9 14.9 0.0016 18.6 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO70804.1 - 5.4e-05 23.2 12.8 0.0055 16.9 1.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO70804.1 - 1.4 9.1 4.9 1.7 8.8 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AAA_25 PF13481.1 AEO70806.1 - 4.4e-06 26.2 0.3 2.2e-05 23.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 AEO70806.1 - 4.8e-05 22.5 0.0 0.00021 20.4 0.0 1.8 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_19 PF13245.1 AEO70806.1 - 0.00014 21.5 0.1 0.00033 20.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain Rad51 PF08423.6 AEO70806.1 - 0.00024 20.1 0.0 0.0017 17.2 0.0 2.3 2 1 0 2 2 2 1 Rad51 KaiC PF06745.8 AEO70806.1 - 0.00038 19.6 0.0 0.001 18.2 0.0 1.7 2 0 0 2 2 2 1 KaiC DnaB_C PF03796.10 AEO70806.1 - 0.0071 15.2 0.0 1.4 7.6 0.0 2.2 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain AAA_28 PF13521.1 AEO70806.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 AEO70806.1 - 0.086 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 AEO70806.1 - 0.14 11.5 0.1 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.11 AEO70806.1 - 0.18 10.9 0.0 0.44 9.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Pex14_N PF04695.8 AEO70807.1 - 0.24 11.4 5.3 0.43 10.6 3.7 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tachystatin_B PF11478.3 AEO70807.1 - 0.61 9.8 4.2 1.6 8.5 2.9 1.7 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B Sporozoite_P67 PF05642.6 AEO70807.1 - 0.64 7.8 14.0 0.77 7.5 9.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen EcKinase PF02958.15 AEO70809.1 - 0.11 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Sugar_tr PF00083.19 AEO70810.1 - 6.9e-114 380.8 27.0 7.9e-114 380.6 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO70810.1 - 5.4e-19 68.1 50.3 7.2e-14 51.2 18.7 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily PUCC PF03209.10 AEO70810.1 - 0.00035 19.4 4.8 0.00035 19.4 3.4 1.8 2 0 0 2 2 2 1 PUCC protein DUF3154 PF11351.3 AEO70810.1 - 2.8 7.7 6.0 1.4 8.6 1.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3154) ABC_tran PF00005.22 AEO70811.1 - 1.2e-40 138.9 1.1 1.6e-18 67.2 0.1 3.8 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 AEO70811.1 - 7.8e-14 52.3 0.6 0.0076 16.2 0.0 4.2 4 0 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 AEO70811.1 - 1.5e-09 37.6 7.8 5.9e-09 35.6 5.4 2.1 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.14 AEO70811.1 - 5.8e-07 28.9 0.8 0.016 14.4 0.0 4.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AEO70811.1 - 9.5e-07 28.2 1.0 0.019 14.4 0.0 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 AEO70811.1 - 2.3e-05 24.3 0.1 0.07 13.0 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 AEO70811.1 - 5.5e-05 23.9 0.7 0.44 11.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 AEO70811.1 - 0.00062 19.6 0.3 0.56 10.0 0.0 3.3 3 0 0 3 3 3 1 Dynamin family AAA_33 PF13671.1 AEO70811.1 - 0.00067 19.5 0.5 0.58 10.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 AEO70811.1 - 0.001 18.7 0.3 0.99 9.1 0.0 3.1 4 0 0 4 4 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 AEO70811.1 - 0.0017 18.5 5.1 2.1 8.4 0.0 4.5 3 2 1 4 4 3 1 AAA domain AAA_28 PF13521.1 AEO70811.1 - 0.0028 17.6 6.5 0.65 9.9 0.1 3.6 3 1 0 3 3 2 2 AAA domain Miro PF08477.8 AEO70811.1 - 0.0041 17.6 0.0 0.68 10.4 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 AEO70811.1 - 0.005 17.1 11.3 0.78 10.0 0.0 3.8 4 0 0 4 4 4 2 AAA domain DUF258 PF03193.11 AEO70811.1 - 0.0072 15.5 0.0 1.5 7.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 AEO70811.1 - 0.0074 16.5 2.9 0.84 9.9 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 AEO70811.1 - 0.009 16.0 1.1 0.009 16.0 0.8 3.6 2 1 1 3 3 3 1 AAA ATPase domain DUF87 PF01935.12 AEO70811.1 - 0.013 15.3 5.2 3.4 7.4 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function DUF87 ArgK PF03308.11 AEO70811.1 - 0.028 13.1 0.5 0.5 9.1 0.1 2.4 2 0 0 2 2 2 0 ArgK protein AAA_10 PF12846.2 AEO70811.1 - 0.037 13.4 0.2 5.5 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA-like domain DUF2877 PF11392.3 AEO70811.1 - 0.049 13.8 1.2 0.21 11.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) Thymidylate_kin PF02223.12 AEO70811.1 - 0.05 12.9 1.4 11 5.3 0.0 3.2 3 0 0 3 3 3 0 Thymidylate kinase Viral_helicase1 PF01443.13 AEO70811.1 - 0.12 11.8 0.2 19 4.7 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Gypsy PF07253.6 AEO70811.1 - 0.21 9.8 0.0 0.34 9.1 0.0 1.2 1 0 0 1 1 1 0 Gypsy protein AAA_13 PF13166.1 AEO70811.1 - 0.34 9.3 7.3 11 4.3 0.0 3.4 4 0 0 4 4 4 0 AAA domain NACHT PF05729.7 AEO70811.1 - 0.47 10.0 0.0 0.47 10.0 0.0 3.4 4 1 0 4 4 2 0 NACHT domain DAGK_cat PF00781.19 AEO70812.1 - 1.6e-09 37.2 0.1 5.6e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain TP_methylase PF00590.15 AEO70812.1 - 0.077 12.6 0.1 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases TRM PF02005.11 AEO70813.1 - 3.3e-107 358.6 0.0 4e-94 315.6 0.0 2.1 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 AEO70813.1 - 0.0012 18.8 0.4 0.0036 17.3 0.3 1.9 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.11 AEO70814.1 - 2e-35 122.1 24.6 1.5e-28 99.5 2.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO70814.1 - 2.8e-10 39.3 2.6 2.8e-10 39.3 1.8 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 AEO70814.1 - 0.00074 18.0 4.0 0.00074 18.0 2.8 2.8 3 1 1 4 4 4 1 MFS/sugar transport protein Inositol_P PF00459.20 AEO70815.1 - 1.1e-61 208.5 0.0 1.3e-61 208.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family His_Phos_2 PF00328.17 AEO70817.1 - 2.7e-59 201.2 0.0 3.1e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3357 PF11837.3 AEO70817.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Sec62 PF03839.11 AEO70819.1 - 1.1e-54 185.2 0.2 1.1e-54 185.2 0.2 1.4 2 0 0 2 2 2 1 Translocation protein Sec62 Zip PF02535.17 AEO70819.1 - 0.001 18.1 0.2 0.015 14.2 0.4 2.1 2 0 0 2 2 2 1 ZIP Zinc transporter SelP_N PF04592.9 AEO70819.1 - 0.046 13.1 10.7 0.096 12.0 7.4 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PAP2_3 PF14378.1 AEO70819.1 - 0.6 9.6 4.0 7.8 5.9 0.4 2.2 1 1 1 2 2 2 0 PAP2 superfamily NST1 PF13945.1 AEO70819.1 - 1.2 9.1 7.5 0.2 11.6 0.8 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator APC_CDC26 PF10471.4 AEO70819.1 - 4.3 8.1 12.3 2.6 8.8 2.7 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Glyco_hydro_43 PF04616.9 AEO70820.1 - 3.8e-55 187.0 3.9 4.8e-55 186.6 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PLDc_2 PF13091.1 AEO70821.1 - 2.5e-12 46.6 0.0 1.1e-05 25.1 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.17 AEO70821.1 - 3.3e-11 42.6 1.7 1.9e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif FR47 PF08445.5 AEO70822.1 - 1.5e-07 31.0 0.0 2.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 AEO70822.1 - 1.5e-07 31.3 0.1 2.3e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AEO70822.1 - 1.2e-05 25.3 0.1 1.9e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO70822.1 - 0.0018 18.3 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO70822.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Thioredoxin PF00085.15 AEO70823.1 - 8.8e-43 144.2 0.1 6.5e-27 93.2 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 AEO70823.1 - 2.4e-13 50.2 0.0 0.00015 21.6 0.0 3.6 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 AEO70823.1 - 2.9e-11 43.5 2.8 2.1e-06 27.8 0.1 4.1 4 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AEO70823.1 - 6.4e-11 42.2 0.9 0.00066 19.7 0.0 5.2 4 1 0 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 AEO70823.1 - 1e-06 28.6 0.1 0.00028 20.8 0.0 2.9 2 0 0 2 2 2 1 Thioredoxin-like HyaE PF07449.6 AEO70823.1 - 4.9e-05 23.1 0.0 0.33 10.8 0.0 4.0 5 0 0 5 5 5 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 AEO70823.1 - 0.0011 18.6 0.1 0.025 14.4 0.0 3.0 4 0 0 4 4 4 1 Thioredoxin domain AhpC-TSA PF00578.16 AEO70823.1 - 0.0028 17.3 3.2 0.55 9.9 0.1 4.0 3 1 0 4 4 4 1 AhpC/TSA family TrbC_Ftype PF09673.5 AEO70823.1 - 0.11 12.1 0.0 7.3 6.2 0.0 3.1 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin assembly protein Thioredoxin_4 PF13462.1 AEO70823.1 - 3 7.8 7.6 5.1 7.0 0.3 3.0 3 0 0 3 3 3 0 Thioredoxin Tyr-DNA_phospho PF06087.7 AEO70824.1 - 3.9e-132 441.0 0.0 4.6e-132 440.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 AEO70824.1 - 0.00069 19.3 0.0 0.2 11.4 0.0 2.7 3 0 0 3 3 3 2 PLD-like domain ACBP PF00887.14 AEO70825.1 - 3.5e-21 74.6 1.9 8.3e-20 70.2 1.3 2.0 1 1 0 1 1 1 1 Acyl CoA binding protein DUF573 PF04504.9 AEO70825.1 - 0.054 13.7 0.0 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Pyr_redox_2 PF07992.9 AEO70826.1 - 7.6e-17 61.8 0.0 1.3e-16 61.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO70826.1 - 3.9e-10 39.9 5.9 7.1e-08 32.7 1.2 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO70826.1 - 3.7e-08 33.6 1.2 0.0002 21.4 0.2 3.1 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO70826.1 - 3.9e-06 26.0 0.2 0.00044 19.2 0.1 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 AEO70826.1 - 0.0073 16.0 1.2 3.4 7.4 0.0 3.7 3 1 1 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 AEO70826.1 - 0.0099 14.8 7.9 4.2 6.1 0.0 3.5 3 1 1 4 4 4 3 FAD dependent oxidoreductase HI0933_like PF03486.9 AEO70826.1 - 0.032 12.6 0.1 7.6 4.8 0.0 3.1 3 1 0 3 3 3 0 HI0933-like protein NAD_binding_8 PF13450.1 AEO70826.1 - 0.075 13.0 3.6 0.78 9.8 0.0 3.4 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 AEO70826.1 - 0.11 11.4 1.2 0.3 9.9 0.0 2.2 2 1 0 2 2 2 0 Lycopene cyclase protein End3 PF12761.2 AEO70827.1 - 1.3e-72 243.6 3.4 1.7e-72 243.1 2.3 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 AEO70827.1 - 3.5e-50 168.0 0.0 6.8e-49 163.9 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 AEO70827.1 - 9.1e-07 27.7 0.2 2.2e-06 26.5 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 AEO70827.1 - 4.1e-06 26.8 0.0 5.9e-05 23.1 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 AEO70827.1 - 4.5e-06 26.1 0.1 1.2e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 AEO70827.1 - 0.00015 21.3 0.1 0.0051 16.5 0.2 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 AEO70827.1 - 0.0058 15.9 0.2 0.017 14.4 0.1 1.8 1 0 0 1 1 1 1 EF hand MDMPI_N PF11716.3 AEO70827.1 - 0.11 12.9 0.0 0.11 12.9 0.0 3.0 2 1 0 3 3 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain DUF641 PF04859.7 AEO70827.1 - 0.26 11.0 5.0 0.073 12.8 1.1 1.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) COG2 PF06148.6 AEO70827.1 - 0.49 10.2 2.4 0.88 9.4 0.2 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PilJ PF13675.1 AEO70827.1 - 0.65 10.3 8.4 0.85 9.9 0.8 3.4 2 2 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Mnd1 PF03962.10 AEO70827.1 - 0.89 9.1 6.7 2.9 7.5 4.7 1.8 1 1 0 1 1 1 0 Mnd1 family TPR_MLP1_2 PF07926.7 AEO70827.1 - 1.9 8.2 7.5 6.8 6.4 0.2 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Med9 PF07544.8 AEO70827.1 - 3.1 7.5 7.4 0.77 9.5 1.9 2.3 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.10 AEO70827.1 - 3.6 7.1 6.4 3.2 7.3 0.2 3.0 3 0 0 3 3 3 0 Septum formation initiator MerR-DNA-bind PF09278.6 AEO70827.1 - 7.7 6.9 16.4 0.52 10.7 1.2 3.5 3 0 0 3 3 3 0 MerR, DNA binding DUF3148 PF11347.3 AEO70828.1 - 0.13 11.9 0.1 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) CENP-Q PF13094.1 AEO70830.1 - 0.028 14.4 1.5 0.028 14.4 1.0 3.3 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4201 PF13870.1 AEO70830.1 - 0.1 12.0 6.2 1.5 8.2 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Cep57_MT_bd PF06657.8 AEO70830.1 - 0.11 12.4 4.6 1.9 8.5 0.1 3.4 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF2205 PF10224.4 AEO70830.1 - 1.5 8.4 5.3 3.3 7.3 0.8 2.5 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 AEO70830.1 - 4.2 7.7 9.8 6.1 7.2 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF972) GRAM PF02893.15 AEO70831.1 - 7.6e-17 60.6 0.0 1.3e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 GRAM domain OPT PF03169.10 AEO70832.1 - 1.1e-209 697.9 29.6 1.3e-209 697.7 20.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein 5-FTHF_cyc-lig PF01812.15 AEO70833.1 - 4.4e-18 65.7 0.0 5.3e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.17 AEO70834.1 - 4e-14 51.8 0.5 4.9e-14 51.6 0.3 1.1 1 0 0 1 1 1 1 LSM domain DUF777 PF05606.6 AEO70834.1 - 0.051 12.7 0.1 0.065 12.4 0.1 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) Xpo1 PF08389.7 AEO70835.1 - 1.4e-26 93.1 0.1 6.1e-26 91.0 0.1 2.2 1 0 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.14 AEO70835.1 - 1.4e-05 24.8 0.9 0.0001 22.1 0.0 2.8 2 1 1 3 3 3 1 Importin-beta N-terminal domain HEAT_EZ PF13513.1 AEO70835.1 - 0.01 16.3 1.0 5.7 7.5 0.0 5.3 5 0 0 5 5 5 0 HEAT-like repeat Dioxygenase_C PF00775.16 AEO70837.1 - 5.2e-12 45.4 1.4 1.3e-11 44.0 0.9 1.7 1 1 0 1 1 1 1 Dioxygenase DUF4360 PF14273.1 AEO70839.1 - 8.1e-38 129.9 0.7 1.4e-37 129.0 0.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) Pyr_redox_2 PF07992.9 AEO70840.1 - 5.8e-14 52.4 0.0 9.7e-10 38.6 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO70840.1 - 2.9e-05 23.1 0.3 0.00011 21.3 0.0 1.8 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 AEO70840.1 - 0.00018 21.3 4.6 0.012 15.3 0.1 2.3 1 1 1 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 AEO70840.1 - 0.00031 20.8 4.4 0.0084 16.1 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AEO70840.1 - 1.4 7.6 4.8 7.2 5.3 0.1 2.0 1 1 1 2 2 2 0 Glucose inhibited division protein A adh_short PF00106.20 AEO70842.1 - 7.1e-17 61.8 0.0 9.2e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO70842.1 - 4.2e-09 36.3 0.0 5.3e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO70842.1 - 0.00075 19.3 0.0 0.00092 19.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AEO70842.1 - 0.046 13.1 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO70842.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding ADH_zinc_N PF00107.21 AEO70843.1 - 5.2e-18 64.8 0.0 7.7e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO70843.1 - 1.1e-06 29.5 0.1 4e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 AEO70843.1 - 0.0028 16.8 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 AEO70843.1 - 0.0068 16.0 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CoA_binding PF02629.14 AEO70843.1 - 0.017 15.5 0.1 2 8.9 0.0 2.5 2 1 0 2 2 2 0 CoA binding domain NAD_binding_10 PF13460.1 AEO70843.1 - 0.024 14.6 0.1 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding AlaDh_PNT_C PF01262.16 AEO70843.1 - 0.05 13.1 0.1 0.083 12.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CPSase_L_chain PF00289.17 AEO70843.1 - 0.093 12.8 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Glyco_transf_9 PF01075.12 AEO70843.1 - 0.1 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) TrkA_N PF02254.13 AEO70843.1 - 0.11 12.4 0.1 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain ADH_N PF08240.7 AEO70844.1 - 1.9e-11 43.7 0.5 2.4e-11 43.3 0.3 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 AEO70845.1 - 8.6e-27 93.7 57.4 1.4e-25 89.7 39.7 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily NADH_dh_m_C1 PF15088.1 AEO70845.1 - 0.053 13.0 0.4 0.18 11.3 0.3 1.9 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Fungal_trans PF04082.13 AEO70848.1 - 4.8e-26 91.2 0.1 7.1e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO70848.1 - 7.9e-07 28.8 9.4 1.3e-06 28.1 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_76 PF03663.9 AEO70851.1 - 8.4e-139 463.0 9.3 1.1e-138 462.7 6.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Pkinase PF00069.20 AEO70852.1 - 3.8e-25 88.5 0.0 7.9e-25 87.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO70852.1 - 1.6e-05 24.0 0.1 0.0071 15.4 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase NPR3 PF03666.8 AEO70853.1 - 0.028 12.9 17.8 0.029 12.8 12.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BSP_II PF05432.6 AEO70853.1 - 0.04 13.1 16.0 0.045 13.0 11.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2413 PF10310.4 AEO70853.1 - 0.061 12.1 20.0 0.06 12.1 13.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) BUD22 PF09073.5 AEO70853.1 - 0.12 11.4 32.6 0.13 11.3 22.6 1.0 1 0 0 1 1 1 0 BUD22 POM121 PF15229.1 AEO70853.1 - 0.15 11.4 15.6 0.17 11.2 10.8 1.0 1 0 0 1 1 1 0 POM121 family FAM60A PF15396.1 AEO70853.1 - 0.21 11.3 16.0 0.22 11.2 11.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A FLO_LFY PF01698.11 AEO70853.1 - 0.22 10.3 26.3 0.26 10.1 18.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Ctr PF04145.10 AEO70853.1 - 0.25 11.3 3.6 0.31 11.0 2.5 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Pox_Ag35 PF03286.9 AEO70853.1 - 0.4 10.1 32.7 0.46 9.9 22.7 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Myc_N PF01056.13 AEO70853.1 - 0.45 9.6 9.9 0.48 9.5 6.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Rtf2 PF04641.7 AEO70853.1 - 0.5 9.5 28.7 0.7 9.0 19.9 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1510 PF07423.6 AEO70853.1 - 0.61 9.4 29.2 0.73 9.1 20.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 AEO70853.1 - 1.3 8.3 26.8 1.6 8.1 18.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF3807 PF12720.2 AEO70853.1 - 1.5 8.9 22.5 1.7 8.7 15.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Hom_end_hint PF05203.11 AEO70853.1 - 2.1 7.9 11.8 2.1 8.0 8.2 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Raftlin PF15250.1 AEO70853.1 - 2.4 6.5 13.4 2.4 6.6 9.3 1.1 1 0 0 1 1 1 0 Raftlin Gti1_Pac2 PF09729.4 AEO70853.1 - 3.1 7.6 14.3 4 7.2 9.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family CDC27 PF09507.5 AEO70853.1 - 3.1 6.9 33.2 3.4 6.7 23.0 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SAPS PF04499.10 AEO70853.1 - 3.5 6.1 12.1 3.4 6.2 8.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.17 AEO70853.1 - 3.7 6.4 10.5 3.5 6.5 7.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Otopetrin PF03189.8 AEO70853.1 - 4 6.3 7.4 3.9 6.3 5.1 1.0 1 0 0 1 1 1 0 Otopetrin U79_P34 PF03064.11 AEO70853.1 - 4.2 6.8 26.7 4.4 6.7 18.5 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1168 PF06658.7 AEO70853.1 - 5.1 6.5 43.6 6.1 6.3 30.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) NCKAP5 PF15246.1 AEO70853.1 - 5.2 6.3 28.1 5.7 6.2 19.5 1.0 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Pilt PF15453.1 AEO70853.1 - 6 6.4 14.6 6.3 6.3 10.1 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Folate_carrier PF01770.13 AEO70853.1 - 6.2 5.2 10.5 6.6 5.1 7.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier AUX_IAA PF02309.11 AEO70853.1 - 6.4 6.4 18.1 7.7 6.1 12.5 1.1 1 0 0 1 1 1 0 AUX/IAA family TT_ORF2 PF02957.10 AEO70853.1 - 6.8 7.4 11.4 8.9 7.0 7.9 1.2 1 0 0 1 1 1 0 TT viral ORF2 DUF3353 PF11833.3 AEO70853.1 - 7.1 6.0 11.0 41 3.5 7.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) eIF-3_zeta PF05091.7 AEO70853.1 - 7.1 5.1 17.2 8 4.9 11.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2151 PF10221.4 AEO70853.1 - 7.9 4.5 14.9 7.6 4.5 10.3 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Tim54 PF11711.3 AEO70853.1 - 8.4 4.8 17.7 10 4.6 12.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Vfa1 PF08432.5 AEO70853.1 - 8.7 6.3 36.5 9.9 6.1 25.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Paramyxo_ncap PF00973.14 AEO70853.1 - 8.9 4.8 13.0 9 4.8 9.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3513 PF12026.3 AEO70853.1 - 9.3 5.7 15.5 10 5.5 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Cupin_2 PF07883.6 AEO70854.1 - 1.1e-08 34.4 1.8 4.3e-08 32.5 1.0 2.2 1 1 1 2 2 2 1 Cupin domain DUF3328 PF11807.3 AEO70855.1 - 2.6e-34 118.8 0.4 3.4e-34 118.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_28 PF00295.12 AEO70856.1 - 4.2e-31 108.1 7.6 5.3e-31 107.7 5.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 AEO70856.1 - 4.8e-10 39.9 10.4 1.4e-09 38.4 7.1 1.9 1 1 0 1 1 1 1 Pectate lyase superfamily protein CX PF01705.14 AEO70856.1 - 0.11 12.4 0.1 0.49 10.3 0.1 2.0 1 1 0 1 1 1 0 CX module SMC_Nse1 PF07574.8 AEO70857.1 - 1.4e-40 139.1 0.0 2.4e-40 138.2 0.0 1.4 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 AEO70857.1 - 1.3e-10 41.0 7.5 1.9e-10 40.5 5.2 1.3 1 0 0 1 1 1 1 RING-like domain PBP1_TM PF14812.1 AEO70857.1 - 2 8.7 6.0 0.49 10.7 0.3 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DZR PF12773.2 AEO70857.1 - 4.5 7.1 8.4 17 5.3 5.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon SPRY PF00622.23 AEO70858.1 - 1.2e-08 35.0 0.0 1.8e-07 31.2 0.0 2.6 3 0 0 3 3 3 1 SPRY domain Myb_Cef PF11831.3 AEO70859.1 - 2.2e-62 210.3 12.2 2.2e-62 210.3 8.4 3.1 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.1 AEO70859.1 - 1.5e-21 76.2 8.8 5.2e-15 55.2 2.2 3.7 3 1 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO70859.1 - 1.4e-20 73.1 4.2 2.3e-09 37.1 0.2 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.3 AEO70859.1 - 0.012 15.4 1.5 0.69 9.8 0.0 3.6 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain EAV_GS PF01309.13 AEO70860.1 - 0.024 14.1 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein Hexokinase_2 PF03727.11 AEO70861.1 - 2.2e-20 72.9 0.0 4.7e-20 71.8 0.0 1.5 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.16 AEO70861.1 - 6e-18 64.9 0.0 1.1e-17 64.0 0.0 1.4 1 1 0 1 1 1 1 Hexokinase GILT PF03227.11 AEO70862.1 - 2.1e-14 53.2 0.2 3.3e-14 52.6 0.1 1.4 1 1 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DcpS_C PF11969.3 AEO70863.1 - 3.7e-29 101.2 0.0 5.6e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 AEO70863.1 - 4.1e-27 94.7 0.0 6.5e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal CHASE3 PF05227.8 AEO70864.1 - 1.3 8.7 7.6 0.43 10.2 0.1 3.0 3 0 0 3 3 3 0 CHASE3 domain TFCD_C PF12612.3 AEO70865.1 - 3.5e-36 124.4 1.0 3.5e-36 124.4 0.7 1.9 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 AEO70865.1 - 0.057 13.5 13.9 0.12 12.5 0.0 6.7 6 1 1 7 7 7 0 HEAT repeat Cnd1 PF12717.2 AEO70865.1 - 0.18 11.6 0.3 1e+02 2.6 0.0 4.0 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Glyco_hydro_76 PF03663.9 AEO70866.1 - 9.1e-49 166.7 12.1 1.2e-48 166.3 8.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 AEO70866.1 - 0.0012 17.9 3.5 0.076 12.0 0.0 2.9 1 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 zf-MIZ PF02891.15 AEO70867.1 - 0.036 13.5 1.6 0.036 13.5 1.1 2.3 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger zf-B_box PF00643.19 AEO70867.1 - 9.6 6.1 10.3 21 5.1 5.6 2.4 2 1 0 2 2 2 0 B-box zinc finger His_Phos_2 PF00328.17 AEO70869.1 - 2.8e-130 434.6 1.1 3.7e-130 434.3 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 AEO70869.1 - 8.3e-08 31.9 0.0 1.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 AEO70870.1 - 3e-78 262.1 0.0 4.1e-78 261.7 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 AEO70870.1 - 1.8e-26 91.0 21.0 3.6e-05 23.4 0.5 8.5 8 0 0 8 8 8 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 AEO70870.1 - 5.8e-05 21.5 0.0 0.00011 20.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.3 AEO70870.1 - 0.00029 19.0 0.8 8.8 4.3 0.0 3.9 2 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AEO70870.1 - 0.002 16.9 0.2 1.2 7.7 0.0 2.9 2 1 0 3 3 3 2 Nup133 N terminal like JAB PF01398.16 AEO70871.1 - 8.2e-10 38.4 0.0 1.8e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Enamelin PF15362.1 AEO70871.1 - 0.14 10.1 1.8 0.36 8.8 0.5 1.9 2 0 0 2 2 2 0 Enamelin ADH_N PF08240.7 AEO70873.1 - 2.2e-27 94.9 1.7 4.9e-27 93.8 1.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO70873.1 - 7.9e-16 57.7 0.7 1.8e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 AEO70873.1 - 0.016 14.5 0.2 0.054 12.8 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 AEO70873.1 - 0.022 14.8 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 AEO70873.1 - 0.022 14.8 0.0 0.059 13.4 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 AEO70873.1 - 0.032 13.1 0.1 0.046 12.6 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.16 AEO70873.1 - 0.04 13.7 0.8 0.081 12.7 0.6 1.4 1 0 0 1 1 1 0 ThiF family NAD_binding_8 PF13450.1 AEO70873.1 - 0.043 13.8 0.2 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 AEO70873.1 - 0.07 12.5 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA zf-C2H2 PF00096.21 AEO70873.1 - 0.42 11.0 2.2 1.1 9.7 1.5 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Vps5 PF09325.5 AEO70875.1 - 1.4e-14 53.9 0.9 2e-14 53.4 0.6 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 AEO70875.1 - 2.5e-08 33.6 0.0 5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 PX domain PAT1 PF09770.4 AEO70875.1 - 0.76 7.9 20.7 1.3 7.1 14.3 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GTP_EFTU PF00009.22 AEO70876.1 - 6.2e-51 172.5 0.0 1e-50 171.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 AEO70876.1 - 5e-23 80.7 0.0 1.1e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 AEO70876.1 - 1.5e-09 37.6 0.0 0.0019 18.0 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus MMR_HSR1 PF01926.18 AEO70876.1 - 0.03 14.2 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Lipase_GDSL_2 PF13472.1 AEO70878.1 - 1.7e-15 57.6 0.4 2.1e-15 57.3 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO70878.1 - 2.2e-09 37.5 0.4 4.2e-08 33.2 0.3 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HTH_35 PF13693.1 AEO70878.1 - 0.022 14.5 0.0 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sulf_transp PF04143.9 AEO70879.1 - 1.6e-14 53.6 34.4 6.2e-09 35.7 7.3 4.3 2 1 1 3 3 3 2 Sulphur transport DUF4341 PF14241.1 AEO70879.1 - 0.0014 18.2 8.8 0.0014 18.2 6.1 5.8 4 2 0 4 4 4 1 Domain of unknown function (DUF4341) Lactamase_B PF00753.22 AEO70880.1 - 2.2e-17 63.3 0.8 2.7e-17 63.0 0.6 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AEO70880.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Kelch_5 PF13854.1 AEO70882.1 - 1.8e-15 56.4 5.5 9.9e-14 50.9 0.4 4.6 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 AEO70882.1 - 4.6e-06 26.3 1.3 0.097 12.4 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 AEO70882.1 - 9.3e-06 25.6 8.5 0.0002 21.4 0.1 5.7 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_1 PF01344.20 AEO70882.1 - 9.9e-06 25.0 1.6 0.94 9.0 0.1 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 AEO70882.1 - 1.6e-05 24.8 6.9 0.18 12.0 0.1 5.9 6 1 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 AEO70882.1 - 0.0034 17.0 1.3 8.4 6.3 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Ribonuc_L-PSP PF01042.16 AEO70883.1 - 5.7e-27 93.8 0.2 6.4e-27 93.7 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Actin PF00022.14 AEO70884.1 - 4.4e-19 68.1 0.0 1.4e-15 56.6 0.0 2.1 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.8 AEO70884.1 - 2.3e-05 23.1 0.0 0.0019 16.8 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein IBR PF01485.16 AEO70885.1 - 1.1e-06 28.3 5.0 1.1e-06 28.3 3.5 5.6 6 2 0 6 6 6 2 IBR domain FdtA PF05523.6 AEO70885.1 - 0.22 11.0 0.0 0.39 10.2 0.0 1.3 1 0 0 1 1 1 0 WxcM-like, C-terminal DAP10 PF07213.6 AEO70886.1 - 0.00049 19.7 0.5 0.00079 19.1 0.4 1.3 1 0 0 1 1 1 1 DAP10 membrane protein PDGLE PF13190.1 AEO70886.1 - 0.027 14.1 2.6 0.039 13.6 1.8 1.4 1 0 0 1 1 1 0 PDGLE domain DUF4145 PF13643.1 AEO70889.1 - 0.17 11.7 0.2 0.17 11.7 0.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) DUF500 PF04366.7 AEO70890.1 - 7.7e-31 106.1 0.0 1.3e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) PBP1_TM PF14812.1 AEO70890.1 - 1.1 9.6 5.9 1.5 9.1 2.6 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal adh_short PF00106.20 AEO70891.1 - 3.1e-63 212.6 8.4 1.6e-31 109.4 0.6 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 AEO70891.1 - 2.1e-31 108.9 2.6 4.8e-15 55.6 0.2 2.6 3 0 0 3 3 3 2 KR domain MaoC_dehydratas PF01575.14 AEO70891.1 - 9.2e-30 102.5 0.0 2.2e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 AEO70891.1 - 9.6e-11 41.5 0.0 2.9e-09 36.8 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Epimerase PF01370.16 AEO70891.1 - 7.2e-05 22.3 4.5 0.0044 16.4 0.1 2.9 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 AEO70891.1 - 8.5e-05 21.6 1.2 0.0011 18.1 0.3 2.3 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4161 PF13722.1 AEO70891.1 - 0.19 12.0 0.5 22 5.3 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) 3HCDH_N PF02737.13 AEO70891.1 - 1.1 8.8 7.7 2.8 7.5 0.6 2.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_17 PF13207.1 AEO70892.1 - 4.3e-07 30.7 0.0 5.4e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 AEO70892.1 - 8.7e-07 28.5 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 AEO70892.1 - 1.2e-05 25.3 0.2 3.5e-05 23.8 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain PRK PF00485.13 AEO70892.1 - 3.8e-05 23.3 0.0 0.00016 21.3 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family ArgK PF03308.11 AEO70892.1 - 0.00037 19.3 0.0 0.00071 18.4 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_18 PF13238.1 AEO70892.1 - 0.00045 20.5 0.0 0.00088 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 AEO70892.1 - 0.0014 17.7 0.0 0.0014 17.6 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain NACHT PF05729.7 AEO70892.1 - 0.0014 18.2 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain MobB PF03205.9 AEO70892.1 - 0.0019 17.8 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 AEO70892.1 - 0.0019 17.6 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 AEO70892.1 - 0.0065 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AEO70892.1 - 0.0067 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 AEO70892.1 - 0.0099 15.6 1.3 0.067 12.9 0.0 2.7 3 0 0 3 3 2 1 Part of AAA domain AAA PF00004.24 AEO70892.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 AEO70892.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_31 PF13614.1 AEO70892.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 AEO70892.1 - 0.015 14.6 0.1 0.089 12.1 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase AAA_33 PF13671.1 AEO70892.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 AEO70892.1 - 0.016 14.9 0.1 0.025 14.3 0.1 1.2 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.1 AEO70892.1 - 0.027 14.6 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AEO70892.1 - 0.04 13.8 0.2 0.097 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 AEO70892.1 - 0.041 13.4 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 AEO70892.1 - 0.053 13.0 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 AEO70892.1 - 0.077 11.8 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain ECM11 PF15463.1 AEO70893.1 - 2.3e-42 144.6 0.3 2.3e-42 144.6 0.2 3.7 4 0 0 4 4 4 1 Extracellular mutant protein 11 TMEM247 PF15444.1 AEO70893.1 - 0.84 9.4 7.6 2 8.1 5.3 1.6 1 0 0 1 1 1 0 Transmembrane protein 247 ParA PF10609.4 AEO70894.1 - 7.6e-35 118.6 0.0 1.5e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 AEO70894.1 - 1.7e-15 56.9 0.0 2.6e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 AEO70894.1 - 3.1e-05 23.1 0.0 5.9e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 AEO70894.1 - 6.1e-05 22.9 0.0 0.00022 21.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 AEO70894.1 - 0.00014 21.0 0.0 0.0067 15.5 0.0 2.3 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 AEO70894.1 - 0.00025 20.4 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 AEO70894.1 - 0.0038 16.4 0.0 0.0067 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_26 PF13500.1 AEO70894.1 - 0.0045 16.6 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AEO70894.1 - 0.0068 16.1 0.3 0.11 12.2 0.2 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 AEO70894.1 - 0.055 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AEO70894.1 - 0.074 13.2 0.0 0.18 12.0 0.0 1.6 1 1 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 AEO70894.1 - 0.08 13.7 0.0 0.13 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 AEO70894.1 - 0.081 11.7 0.1 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 AEO70894.1 - 0.088 12.7 0.1 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 AEO70894.1 - 0.16 11.5 0.1 0.31 10.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cofilin_ADF PF00241.15 AEO70895.1 - 0.00022 21.0 0.0 0.00024 20.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Csm1 PF12539.3 AEO70895.1 - 0.081 13.4 0.1 0.098 13.1 0.0 1.2 1 0 0 1 1 1 0 Chromosome segregation protein Csm1/Pcs1 NUMOD1 PF07453.8 AEO70895.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 NUMOD1 domain MoCF_biosynth PF00994.19 AEO70896.1 - 1.1e-34 118.8 0.0 1.8e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain PcrB PF01884.12 AEO70896.1 - 0.12 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 PcrB family Ras PF00071.17 AEO70897.1 - 7.4e-59 197.7 0.3 8.7e-59 197.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO70897.1 - 3e-19 69.6 0.0 4.5e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO70897.1 - 1.7e-09 37.2 0.0 1.9e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AEO70897.1 - 1.2e-07 31.3 0.1 6.8e-07 28.9 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 AEO70897.1 - 0.00021 20.6 0.2 0.00052 19.3 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 AEO70897.1 - 0.0011 18.8 0.0 0.0018 18.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 AEO70897.1 - 0.0093 15.1 0.2 0.016 14.3 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 AEO70897.1 - 0.023 14.2 2.7 0.17 11.3 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 AEO70897.1 - 0.12 11.8 0.5 0.72 9.2 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.1 AEO70897.1 - 0.15 11.4 0.2 0.24 10.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 AEO70897.1 - 0.17 11.0 0.7 0.36 10.0 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function, DUF258 ADH_zinc_N PF00107.21 AEO70899.1 - 2.1e-19 69.3 0.4 3.7e-19 68.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO70899.1 - 7.1e-10 39.8 1.1 1.4e-09 38.8 0.1 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO70899.1 - 0.00035 20.3 0.1 0.00079 19.1 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain KH_1 PF00013.24 AEO70900.1 - 0.02 14.5 0.1 0.083 12.5 0.0 2.0 2 0 0 2 2 2 0 KH domain KH_4 PF13083.1 AEO70900.1 - 0.036 13.6 0.1 0.092 12.4 0.1 1.7 1 0 0 1 1 1 0 KH domain Pfg27 PF09216.5 AEO70900.1 - 0.076 12.6 0.1 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Pfg27 Ribosomal_60s PF00428.14 AEO70900.1 - 0.47 10.8 7.4 0.99 9.8 5.1 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein BRF1 PF07741.8 AEO70900.1 - 0.81 9.9 9.7 2.5 8.3 6.8 1.9 1 0 0 1 1 1 0 Brf1-like TBP-binding domain GATA PF00320.22 AEO70901.1 - 1.1e-15 56.6 3.0 1.9e-15 55.9 2.1 1.4 1 0 0 1 1 1 1 GATA zinc finger Macoilin PF09726.4 AEO70901.1 - 0.0051 15.1 4.3 0.0059 14.9 3.0 1.2 1 0 0 1 1 1 1 Transmembrane protein TF_Zn_Ribbon PF08271.7 AEO70901.1 - 0.006 15.8 0.5 0.01 15.1 0.4 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding DUF2051 PF09738.4 AEO70901.1 - 0.0073 15.6 8.6 0.0073 15.6 6.0 1.6 1 1 0 1 1 1 1 Double stranded RNA binding protein (DUF2051) DZR PF12773.2 AEO70901.1 - 0.021 14.6 0.4 0.047 13.5 0.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon ATG16 PF08614.6 AEO70901.1 - 0.087 12.6 16.7 0.046 13.5 9.6 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF3220 PF11516.3 AEO70901.1 - 0.12 12.3 1.2 0.84 9.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3120) ArfGap PF01412.13 AEO70901.1 - 0.17 11.6 1.4 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf PilJ PF13675.1 AEO70901.1 - 0.19 12.0 13.8 0.072 13.4 5.8 2.6 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4164 PF13747.1 AEO70901.1 - 0.21 11.7 14.1 0.42 10.7 9.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DDE_Tnp_IS66 PF03050.9 AEO70901.1 - 0.22 10.7 6.4 0.4 9.8 4.4 1.3 1 0 0 1 1 1 0 Transposase IS66 family Tho2 PF11262.3 AEO70901.1 - 0.26 10.2 5.7 0.45 9.5 3.9 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF3584 PF12128.3 AEO70901.1 - 0.43 7.8 15.8 0.72 7.1 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF342 PF03961.8 AEO70901.1 - 0.48 8.7 9.2 0.71 8.2 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) zf-ribbon_3 PF13248.1 AEO70901.1 - 0.57 9.4 3.0 1.5 8.0 2.1 1.7 1 1 0 1 1 1 0 zinc-ribbon domain APG6 PF04111.7 AEO70901.1 - 0.72 8.8 15.5 1.1 8.1 10.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Striatin PF08232.7 AEO70901.1 - 0.75 10.1 19.2 0.29 11.4 3.7 2.7 2 1 1 3 3 3 0 Striatin family HlyD PF00529.15 AEO70901.1 - 1 8.6 20.6 0.15 11.3 11.2 1.7 2 0 0 2 2 2 0 HlyD family secretion protein IncA PF04156.9 AEO70901.1 - 1.1 8.8 16.8 2.3 7.7 11.2 1.8 2 0 0 2 2 2 0 IncA protein Phlebovirus_NSM PF07246.6 AEO70901.1 - 2.2 7.3 7.0 4.6 6.3 4.8 1.5 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Fmp27_WPPW PF10359.4 AEO70901.1 - 2.7 6.3 10.6 4.6 5.5 7.3 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HlyD_2 PF12700.2 AEO70901.1 - 3.5 6.6 6.8 5.5 6.0 4.7 1.2 1 0 0 1 1 1 0 HlyD family secretion protein IFP_35_N PF07334.8 AEO70901.1 - 5.9 6.9 9.9 0.42 10.5 0.9 3.0 1 1 2 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ATAD4 PF15321.1 AEO70901.1 - 9.4 7.3 8.4 7 7.7 3.7 2.2 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 BAF1_ABF1 PF04684.8 AEO70902.1 - 0.38 9.5 14.1 0.15 10.8 5.1 2.1 1 1 1 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 AEO70902.1 - 2.7 6.9 4.7 4.5 6.1 3.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Mit_KHE1 PF10173.4 AEO70903.1 - 4.1e-69 232.1 1.7 6e-69 231.6 1.2 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Sensor PF13796.1 AEO70903.1 - 0.036 13.6 1.5 0.058 12.9 1.0 1.3 1 0 0 1 1 1 0 Putative sensor Cullin PF00888.17 AEO70905.1 - 3.4e-205 683.0 4.0 4.6e-205 682.5 2.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 AEO70905.1 - 2.8e-26 91.1 3.8 2.8e-26 91.1 2.7 2.9 4 0 0 4 4 4 1 Cullin protein neddylation domain Avl9 PF09794.4 AEO70906.1 - 4.4e-124 413.8 0.0 5.8e-124 413.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 AEO70906.1 - 4.3e-07 29.6 0.0 0.00017 21.2 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 AEO70906.1 - 0.00069 18.9 0.2 0.0047 16.2 0.1 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Pkinase PF00069.20 AEO70907.1 - 4.1e-72 242.4 0.0 5e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO70907.1 - 2.4e-31 108.7 0.0 3e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO70907.1 - 2.8e-05 23.2 0.0 9.4e-05 21.5 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AEO70907.1 - 0.00041 19.4 0.0 0.032 13.1 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 AEO70907.1 - 0.00059 19.6 0.1 0.0018 18.0 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 AEO70907.1 - 0.042 13.1 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Phosphorylase PF00343.15 AEO70908.1 - 0 1070.5 0.0 0 1070.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.1 AEO70908.1 - 0.032 13.9 0.0 0.099 12.3 0.0 1.8 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Fringe PF02434.11 AEO70908.1 - 0.041 13.0 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 Fringe-like G-alpha PF00503.15 AEO70909.1 - 1.2e-124 416.0 0.0 1.4e-124 415.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 AEO70909.1 - 1.1e-15 57.3 0.3 5.9e-10 38.6 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AEO70909.1 - 2.9e-05 23.3 0.2 0.12 11.4 0.1 2.4 1 1 1 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 AEO70909.1 - 0.0014 19.0 0.0 0.9 10.0 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 AEO70909.1 - 0.056 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Aspzincin_M35 PF14521.1 AEO70911.1 - 3.3e-05 24.4 0.1 7.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase 3A PF00803.13 AEO70911.1 - 0.015 14.3 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 3A/RNA2 movement protein family Pectate_lyase_3 PF12708.2 AEO70912.1 - 5.2e-68 229.5 29.5 3.1e-58 197.5 11.2 3.1 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 AEO70912.1 - 0.027 13.9 0.9 0.31 10.5 0.3 2.5 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Sporozoite_P67 PF05642.6 AEO70912.1 - 0.31 8.8 23.8 0.65 7.7 16.5 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PDZ_1 PF12812.2 AEO70915.1 - 3.5e-56 187.0 0.0 1.1e-34 118.1 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 AEO70915.1 - 9.4e-16 57.8 0.2 2.9e-13 49.8 0.0 2.7 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.1 AEO70915.1 - 3.1e-15 55.8 0.5 7.4e-06 25.7 0.0 4.5 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.19 AEO70915.1 - 2e-08 34.2 0.0 0.00086 19.4 0.0 3.9 4 0 0 4 4 4 1 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 AEO70915.1 - 0.00019 21.0 0.0 0.00058 19.5 0.0 1.7 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 AEO70915.1 - 0.0065 16.2 0.1 0.3 10.8 0.0 3.3 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 AEO70915.1 - 0.15 11.4 0.1 0.34 10.3 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 AEO70915.1 - 0.36 9.2 0.1 0.68 8.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase S46 DUF31 PF01732.11 AEO70915.1 - 0.54 9.5 0.4 0.82 8.9 0.3 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) DnaJ PF00226.26 AEO70916.1 - 7.4e-20 70.4 0.8 1.3e-19 69.6 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain INCENP_ARK-bind PF03941.10 AEO70917.1 - 7.7e-19 67.2 0.0 2.1e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Borrelia_P83 PF05262.6 AEO70917.1 - 0.0011 17.3 0.0 0.0011 17.3 0.0 2.3 1 1 0 2 2 2 1 Borrelia P83/100 protein SAP PF02037.22 AEO70918.1 - 4.1e-09 35.7 0.2 8.5e-09 34.7 0.1 1.6 1 0 0 1 1 1 1 SAP domain zf-C3HC4 PF00097.20 AEO70918.1 - 1.2e-06 28.0 14.5 1.2e-06 28.0 10.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO70918.1 - 1.5e-06 28.1 15.4 1.5e-06 28.1 10.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO70918.1 - 5.5e-06 25.9 11.7 5.5e-06 25.9 8.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO70918.1 - 1.6e-05 24.5 17.8 1.6e-05 24.4 9.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 AEO70918.1 - 1.6e-05 24.6 18.7 2.3e-05 24.1 9.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 AEO70918.1 - 6.6e-05 22.6 4.6 6.6e-05 22.6 3.2 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein U-box PF04564.10 AEO70918.1 - 0.00038 20.3 0.0 0.00081 19.3 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.1 AEO70918.1 - 0.00046 19.8 6.1 0.00046 19.8 4.2 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AEO70918.1 - 0.0014 18.4 13.9 0.0014 18.4 9.6 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 AEO70918.1 - 0.017 14.6 5.1 0.017 14.6 3.5 3.1 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 AEO70918.1 - 0.028 14.4 7.1 0.028 14.4 4.9 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger Mob_synth_C PF06463.8 AEO70918.1 - 0.032 13.9 3.8 0.092 12.4 2.6 1.8 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-Apc11 PF12861.2 AEO70918.1 - 0.062 13.1 2.9 0.17 11.7 2.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PRP21_like_P PF12230.3 AEO70918.1 - 0.34 10.3 5.1 0.51 9.8 1.5 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-P11 PF03854.9 AEO70918.1 - 4.5 6.8 16.6 0.76 9.2 6.5 2.4 2 0 0 2 2 2 0 P-11 zinc finger Snf7 PF03357.16 AEO70919.1 - 5e-19 68.3 7.0 5e-19 68.3 4.9 1.9 1 1 1 2 2 2 1 Snf7 MutS_III PF05192.13 AEO70919.1 - 0.37 10.5 5.2 0.8 9.4 3.6 1.6 1 0 0 1 1 1 0 MutS domain III Phage_int_SAM_1 PF02899.12 AEO70919.1 - 0.5 10.5 5.2 0.44 10.7 1.3 2.7 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain YlqD PF11068.3 AEO70919.1 - 1.7 8.6 13.0 4 7.4 2.0 2.5 2 0 0 2 2 2 0 YlqD protein HrpA_pilin PF09589.5 AEO70919.1 - 8.8 6.7 9.8 55 4.2 6.9 2.1 1 1 0 1 1 1 0 HrpA pilus formation protein TRAPPC-Trs85 PF12739.2 AEO70920.1 - 4.6e-123 410.9 0.9 6.7e-123 410.3 0.6 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_12 PF13424.1 AEO70920.1 - 0.017 15.0 0.4 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 AEO70920.1 - 0.04 14.2 0.8 7.8 6.9 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Polysacc_deac_1 PF01522.16 AEO70921.1 - 1.4e-14 53.7 0.0 2.7e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 AEO70921.1 - 0.055 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) MCM PF00493.18 AEO70922.1 - 5.5e-139 462.5 2.4 6.2e-139 462.4 0.7 1.7 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 AEO70922.1 - 7e-20 71.7 0.1 3.3e-19 69.5 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 AEO70922.1 - 2.9e-07 29.8 0.0 7.7e-07 28.4 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 AEO70922.1 - 0.00061 19.3 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 AEO70922.1 - 0.0016 18.0 0.0 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AEO70922.1 - 0.0022 17.7 0.0 0.0061 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MOZ_SAS PF01853.13 AEO70923.1 - 7.1e-85 283.0 0.3 9.9e-85 282.5 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 AEO70923.1 - 3.9e-18 64.8 0.0 2.6e-17 62.2 0.0 2.3 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain DUF2316 PF10078.4 AEO70923.1 - 0.021 14.7 0.2 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Acetyltransf_7 PF13508.1 AEO70923.1 - 0.026 14.6 0.0 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO70923.1 - 0.043 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family He_PIG_assoc PF10632.4 AEO70923.1 - 0.15 11.4 0.1 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase DDRGK PF09756.4 AEO70923.1 - 0.74 9.1 0.0 0.74 9.1 0.0 2.6 3 0 0 3 3 3 0 DDRGK domain DUF1299 PF06975.6 AEO70923.1 - 1.7 8.5 5.4 0.64 9.9 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1299) RNase_T PF00929.19 AEO70924.1 - 1.8e-23 83.5 0.0 2.7e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 AEO70924.1 - 0.0061 16.0 0.0 0.026 14.0 0.0 2.1 1 1 0 1 1 1 1 3'-5' exonuclease RNase_H2_suC PF08615.6 AEO70925.1 - 1.2e-25 89.9 0.0 1.4e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Aminotran_1_2 PF00155.16 AEO70926.1 - 7.6e-17 61.3 0.0 6.7e-16 58.1 0.0 2.2 1 1 1 2 2 2 1 Aminotransferase class I and II RNase_Zc3h12a PF11977.3 AEO70926.1 - 0.044 13.6 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain F1F0-ATPsyn_F PF10791.4 AEO70927.1 - 9.6e-37 125.1 0.2 3.7e-36 123.2 0.2 2.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi CCDC144C PF14915.1 AEO70927.1 - 4.5 6.0 8.4 5.5 5.8 0.0 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region ETC_C1_NDUFA4 PF04800.7 AEO70928.1 - 2.8e-37 126.6 0.1 4.3e-37 126.0 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region CLTH PF10607.4 AEO70929.1 - 2.6e-29 101.7 0.2 3.8e-29 101.2 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 AEO70929.1 - 1.9e-09 36.9 0.0 3.7e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 LisH DNA_ligase_IV PF11411.3 AEO70929.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA ligase IV PRK PF00485.13 AEO70930.1 - 5.2e-57 192.5 0.0 7.4e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 AEO70930.1 - 3.5e-40 137.4 0.0 5.4e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 AEO70930.1 - 3.4e-09 37.5 0.1 9.7e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO70930.1 - 1.2e-06 28.8 0.0 2.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 AEO70930.1 - 9e-05 22.1 0.0 0.00035 20.2 0.0 2.0 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 AEO70930.1 - 0.00015 21.7 0.0 0.0013 18.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AEO70930.1 - 0.0046 16.4 0.3 0.015 14.7 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 AEO70930.1 - 0.0048 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.7 AEO70930.1 - 0.0067 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.17 AEO70930.1 - 0.0097 14.7 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain MobB PF03205.9 AEO70930.1 - 0.014 15.0 0.0 0.041 13.5 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 AEO70930.1 - 0.036 13.8 0.0 0.08 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_16 PF13191.1 AEO70930.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 AEO70930.1 - 0.05 12.4 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 AEO70930.1 - 0.13 11.4 0.0 0.29 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Pyr_redox_2 PF07992.9 AEO70931.1 - 1e-24 87.5 0.0 1.4e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO70931.1 - 1.9e-16 60.2 0.0 3.5e-11 43.3 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 AEO70931.1 - 1.8e-07 29.9 0.1 4.4e-07 28.7 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 AEO70931.1 - 6.8e-06 26.1 0.9 1.4e-05 25.1 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 AEO70931.1 - 1.1e-05 24.9 0.3 3.3e-05 23.4 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 AEO70931.1 - 0.00024 20.2 0.5 0.00061 19.0 0.4 1.6 1 0 0 1 1 1 1 EF hand Pyr_redox_3 PF13738.1 AEO70931.1 - 0.00095 19.2 0.0 1.6 8.7 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AEO70931.1 - 0.011 14.6 0.0 1.7 7.4 0.0 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase EF-hand_8 PF13833.1 AEO70931.1 - 0.013 15.1 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair FAD_binding_2 PF00890.19 AEO70931.1 - 0.022 13.5 0.1 5.6 5.6 0.0 2.9 3 0 0 3 3 3 0 FAD binding domain NAD_binding_8 PF13450.1 AEO70931.1 - 0.072 13.1 0.0 0.76 9.8 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PTPS PF01242.14 AEO70931.1 - 0.086 12.5 0.0 10 5.8 0.0 2.6 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase Ank_2 PF12796.2 AEO70932.1 - 6.7e-13 48.7 0.0 0.064 13.6 0.0 5.3 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) NACHT PF05729.7 AEO70932.1 - 2.7e-08 33.6 0.0 1.4e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 NACHT domain Ank PF00023.25 AEO70932.1 - 2.3e-06 27.0 5.2 0.0062 16.3 0.0 5.7 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.1 AEO70932.1 - 5e-06 26.8 3.3 6.8 7.3 0.0 7.1 8 0 0 8 8 8 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO70932.1 - 1.1e-05 25.5 2.1 6.9 7.0 0.0 6.2 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO70932.1 - 1.9e-05 24.4 0.0 1.2 9.5 0.0 5.4 5 0 0 5 5 5 1 Ankyrin repeat AAA_10 PF12846.2 AEO70932.1 - 0.0011 18.4 0.0 0.0042 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain AAA_19 PF13245.1 AEO70932.1 - 0.025 14.3 0.1 0.12 12.1 0.0 2.2 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 AEO70932.1 - 0.044 12.6 0.0 0.091 11.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain HET PF06985.6 AEO70934.1 - 3.4e-18 66.1 7.0 1.2e-16 61.1 0.6 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HTH_39 PF14090.1 AEO70934.1 - 0.073 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1056 PF06341.6 AEO70935.1 - 3.4 7.7 17.5 0.051 13.6 4.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) Nop53 PF07767.6 AEO70936.1 - 5.9e-108 361.3 32.7 7e-108 361.0 22.7 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF3394 PF11874.3 AEO70936.1 - 0.32 10.4 2.8 0.29 10.6 0.7 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3394) Ras PF00071.17 AEO70937.1 - 1.4e-59 200.0 0.3 1.9e-59 199.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO70937.1 - 4.8e-21 75.4 0.0 8.1e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO70937.1 - 7.1e-18 64.4 0.2 8.9e-18 64.1 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AEO70937.1 - 2e-08 33.8 0.0 8.9e-08 31.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AEO70937.1 - 1.9e-06 27.2 0.3 2.3e-06 26.9 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 AEO70937.1 - 9.3e-06 24.9 0.0 1.5e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AEO70937.1 - 9.5e-06 25.5 0.0 1.5e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 AEO70937.1 - 0.01 15.4 0.1 0.033 13.7 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 AEO70937.1 - 0.023 14.6 0.1 1.6 8.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 AEO70937.1 - 0.025 14.3 0.2 3 7.6 0.0 2.5 2 1 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 AEO70937.1 - 0.067 13.0 0.3 0.13 12.1 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AEO70937.1 - 0.11 12.6 0.0 1.1 9.4 0.0 2.4 1 1 0 1 1 1 0 AAA domain Glyco_hydro_3_C PF01915.17 AEO70937.1 - 0.14 11.6 0.7 0.33 10.4 0.4 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Ribosomal_L24e PF01246.15 AEO70938.1 - 3e-27 94.2 3.8 6.4e-27 93.2 2.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e SpoU_sub_bind PF08032.7 AEO70938.1 - 0.077 13.1 0.4 0.22 11.7 0.1 1.9 1 1 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding KIAA1430 PF13879.1 AEO70938.1 - 0.18 12.2 3.6 0.32 11.4 2.5 1.5 1 1 0 1 1 1 0 KIAA1430 homologue FAD_binding_4 PF01565.18 AEO70940.1 - 2.4e-18 65.9 1.8 4.3e-18 65.1 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO70940.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like adh_short PF00106.20 AEO70941.1 - 2.4e-16 60.0 0.3 5.8e-16 58.8 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO70941.1 - 3.6e-05 23.4 0.1 9.1e-05 22.1 0.1 1.6 2 0 0 2 2 2 1 KR domain Tissue_fac PF01108.12 AEO70941.1 - 0.029 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Tissue factor FAD_binding_4 PF01565.18 AEO70942.1 - 2.9e-29 101.3 1.5 5.2e-29 100.5 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO70942.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like YfaZ PF07437.6 AEO70942.1 - 0.024 14.0 0.5 0.024 14.0 0.4 1.7 2 0 0 2 2 2 0 YfaZ precursor DUF3937 PF13073.1 AEO70943.1 - 0.85 9.5 4.8 1.1 9.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3937) CorA PF01544.13 AEO70944.1 - 2.3e-05 23.5 0.0 2.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Prefoldin_2 PF01920.15 AEO70944.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Prefoldin subunit Prothymosin PF03247.9 AEO70946.1 - 0.037 14.1 9.2 0.048 13.8 6.4 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family CENP-B_dimeris PF09026.5 AEO70946.1 - 0.12 12.5 3.4 0.19 12.0 2.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DTHCT PF08070.6 AEO70946.1 - 0.22 12.2 5.5 0.18 12.5 3.0 1.4 1 1 0 1 1 1 0 DTHCT (NUC029) region Spore_coat_CotO PF14153.1 AEO70946.1 - 0.32 10.3 2.7 0.36 10.2 1.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Nucleoplasmin PF03066.10 AEO70946.1 - 0.48 9.9 5.7 0.54 9.7 4.0 1.1 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 AEO70946.1 - 0.93 9.0 7.0 0.97 9.0 4.8 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 AEO70946.1 - 1.1 9.6 8.8 1.6 9.0 6.1 1.5 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-CCHC PF00098.18 AEO70947.1 - 1.3e-13 50.1 15.4 5.5e-05 22.8 0.2 3.4 3 0 0 3 3 3 3 Zinc knuckle Retrotrans_gag PF03732.12 AEO70947.1 - 2.4e-07 30.7 0.0 4.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_4 PF14392.1 AEO70947.1 - 4.3e-05 23.0 12.4 0.11 12.1 0.3 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.1 AEO70947.1 - 0.15 11.7 7.7 0.49 10.1 0.6 3.3 2 1 1 3 3 3 0 Zinc knuckle UBN2 PF14223.1 AEO70947.1 - 0.2 11.4 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RNA_pol_N PF01194.12 AEO70947.1 - 0.39 10.7 4.8 0.34 10.9 0.7 2.4 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit zf-CCHC_2 PF13696.1 AEO70947.1 - 1.7 8.2 13.7 0.94 9.0 1.3 3.7 2 1 1 3 3 3 0 Zinc knuckle Kei1 PF08552.6 AEO70948.1 - 2.1e-52 177.5 0.2 2.5e-52 177.2 0.1 1.0 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 NIR_SIR PF01077.17 AEO70949.1 - 7e-56 187.9 0.2 4.9e-49 165.6 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 AEO70949.1 - 3.1e-31 106.8 0.1 6.9e-15 54.4 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 AEO70949.1 - 2.1e-28 99.1 0.0 4.8e-28 97.9 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 AEO70949.1 - 2.1e-08 33.9 0.4 1.3e-07 31.3 0.1 2.2 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Chitin_synth_1 PF01644.12 AEO70950.1 - 1.3e-85 285.2 0.3 1.9e-85 284.6 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 AEO70950.1 - 7.6e-33 112.0 0.1 1.6e-32 111.0 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 AEO70950.1 - 2.2e-23 82.4 3.9 1.1e-20 73.5 0.0 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 AEO70950.1 - 3.1e-10 40.0 0.5 3.1e-10 40.0 0.4 2.4 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AEO70950.1 - 1.3e-05 25.1 0.0 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 MARVEL PF01284.18 AEO70951.1 - 1.8e-23 82.9 0.3 2.1e-23 82.7 0.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain CD20 PF04103.10 AEO70951.1 - 0.11 12.3 4.4 0.18 11.7 3.0 1.5 1 1 0 1 1 1 0 CD20-like family Phage_holin_2 PF04550.7 AEO70951.1 - 0.57 10.3 7.1 5.3 7.2 4.7 2.1 1 1 0 1 1 1 0 Phage holin family 2 Macoilin PF09726.4 AEO70952.1 - 3.4 5.8 8.1 4.1 5.5 5.6 1.0 1 0 0 1 1 1 0 Transmembrane protein CCDC14 PF15254.1 AEO70952.1 - 3.8 5.7 9.6 4.4 5.5 6.7 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 Adaptin_N PF01602.15 AEO70953.1 - 2.7e-136 455.0 5.2 3.3e-136 454.7 3.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 AEO70953.1 - 2.4e-19 69.8 1.1 8.4e-19 68.0 0.0 2.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 AEO70953.1 - 3.6e-18 65.6 5.2 1.1e-11 44.7 0.1 4.7 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 AEO70953.1 - 6.8e-14 50.6 2.8 6.7e-05 22.6 0.0 5.1 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 AEO70953.1 - 6.3e-06 26.5 4.3 0.23 11.9 0.0 6.1 5 1 1 6 6 6 2 HEAT-like repeat CLASP_N PF12348.3 AEO70953.1 - 4e-05 23.0 0.9 0.045 13.0 0.0 3.3 3 1 0 3 3 3 2 CLASP N terminal Arm PF00514.18 AEO70953.1 - 0.00033 20.3 0.8 3.7 7.5 0.0 5.2 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 AEO70953.1 - 0.0039 17.0 1.1 0.13 12.1 0.0 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) Atx10homo_assoc PF09759.4 AEO70953.1 - 0.008 15.9 0.0 0.51 10.0 0.0 3.4 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Glyco_hydro_62 PF03664.8 AEO70954.1 - 3.6e-142 472.2 9.9 4.3e-142 472.0 6.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.13 AEO70954.1 - 7e-14 51.1 14.0 1.6e-13 50.0 9.7 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 AEO70954.1 - 0.87 9.6 3.6 1.6 8.7 2.5 1.4 1 0 0 1 1 1 0 Toxin 7 DUF1517 PF07466.6 AEO70954.1 - 1.6 7.6 7.8 4.2 6.2 5.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF1077 PF06417.7 AEO70955.1 - 1.3e-54 182.8 2.3 1.5e-54 182.6 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Galactosyl_T PF01762.16 AEO70956.1 - 5.4e-15 55.4 0.4 8.7e-15 54.8 0.3 1.3 1 0 0 1 1 1 1 Galactosyltransferase Glyco_trans_2_3 PF13632.1 AEO70956.1 - 0.11 12.2 1.1 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family group 2 UMP1 PF05348.6 AEO70958.1 - 5.5e-23 81.3 0.0 6.9e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 ABC_tran PF00005.22 AEO70959.1 - 1e-23 84.1 0.0 2.3e-10 40.9 0.0 3.5 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AEO70959.1 - 2.3e-09 37.6 0.3 0.0094 15.9 0.0 3.4 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 AEO70959.1 - 3.8e-08 34.1 0.0 0.0044 17.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 AEO70959.1 - 2.9e-06 27.1 0.0 0.013 15.4 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 AEO70959.1 - 1.8e-05 24.1 0.1 0.026 14.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 AEO70959.1 - 6.9e-05 23.2 0.1 0.072 13.4 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AEO70959.1 - 0.00029 20.8 0.2 0.33 10.8 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 AEO70959.1 - 0.0018 18.4 0.0 0.86 9.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 AEO70959.1 - 0.0019 17.6 0.0 2.8 7.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.1 AEO70959.1 - 0.0024 17.7 0.0 0.74 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AEO70959.1 - 0.0036 17.5 0.0 2.9 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 AEO70959.1 - 0.0039 17.6 0.0 0.2 12.1 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 AEO70959.1 - 0.008 15.8 0.0 2.7 7.6 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 AEO70959.1 - 0.01 15.2 0.0 3.6 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 AEO70959.1 - 0.017 15.0 0.0 3.6 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 AEO70959.1 - 0.025 14.5 0.0 10 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AEO70959.1 - 0.033 14.3 0.0 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.4 AEO70959.1 - 0.043 13.3 0.0 0.42 10.1 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 AEO70959.1 - 0.049 13.8 0.0 0.76 9.9 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 AEO70959.1 - 0.081 12.1 0.0 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 AEO70959.1 - 0.094 12.2 0.0 9.9 5.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 AEO70959.1 - 0.1 12.2 0.0 16 5.1 0.0 2.8 3 0 0 3 3 3 0 NACHT domain ATP-synt_ab PF00006.20 AEO70959.1 - 0.13 11.7 0.0 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SRPRB PF09439.5 AEO70959.1 - 0.22 10.6 0.0 13 4.9 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_13 PF13166.1 AEO70959.1 - 0.3 9.4 0.1 0.51 8.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 AEO70959.1 - 0.3 10.5 0.0 2.8 7.4 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Kinesin PF00225.18 AEO70961.1 - 6.7e-56 189.4 0.0 1.3e-55 188.4 0.0 1.5 1 1 0 1 1 1 1 Kinesin motor domain HALZ PF02183.13 AEO70961.1 - 0.043 13.5 0.3 0.043 13.5 0.2 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Herpes_BLRF2 PF05812.7 AEO70961.1 - 0.052 13.3 4.8 2 8.2 0.6 2.5 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein RIX1 PF08167.7 AEO70961.1 - 0.093 12.4 0.1 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis Kinetocho_Slk19 PF12709.2 AEO70961.1 - 0.35 10.9 4.0 2.4 8.2 0.2 2.4 2 0 0 2 2 2 0 Central kinetochore-associated DivIVA PF05103.8 AEO70961.1 - 0.6 10.1 3.4 12 5.9 0.0 2.4 2 0 0 2 2 2 0 DivIVA protein RXT2_N PF08595.6 AEO70962.1 - 2 8.2 7.4 5.6 6.7 5.1 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal LMWPc PF01451.16 AEO70963.1 - 0.0063 16.8 0.0 5.3 7.3 0.0 2.5 2 1 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase zf-C3HC4_2 PF13923.1 AEO70964.1 - 0.0087 16.0 0.6 0.0087 16.0 0.4 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO70964.1 - 0.013 15.1 6.8 0.081 12.6 2.2 3.0 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 AEO70964.1 - 0.047 13.4 1.0 0.047 13.4 0.7 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.20 AEO70964.1 - 0.46 10.1 6.3 0.15 11.7 1.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) EB PF01683.13 AEO70966.1 - 0.0078 16.2 14.5 0.15 12.1 5.3 2.5 2 1 0 2 2 2 2 EB module Nodulin_late PF07127.6 AEO70966.1 - 8.8 6.5 12.8 2 8.6 0.1 2.8 2 1 0 2 2 2 0 Late nodulin protein PLDc_N PF13396.1 AEO70967.1 - 3.1e-09 36.3 0.9 4.9e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal TMEM125 PF15109.1 AEO70967.1 - 0.028 14.5 2.1 0.9 9.6 0.8 2.0 2 0 0 2 2 2 0 TMEM125 protein family DUF21 PF01595.15 AEO70967.1 - 0.034 13.4 1.2 4 6.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF21 DUF2781 PF10914.3 AEO70967.1 - 0.036 13.8 0.3 0.049 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) RAMP4 PF06624.7 AEO70967.1 - 0.17 11.4 0.2 2.5 7.6 0.1 2.2 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Pkinase_Tyr PF07714.12 AEO70969.1 - 5.9e-18 64.8 0.0 3.2e-17 62.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 AEO70969.1 - 3.4e-17 62.4 0.0 4.4e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 AEO70969.1 - 0.0074 15.2 0.0 0.012 14.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like GMC_oxred_C PF05199.8 AEO70970.1 - 1.3e-14 54.6 0.0 1.4e-14 54.5 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Pkinase PF00069.20 AEO70971.1 - 1.1e-38 132.8 0.0 2.3e-38 131.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO70971.1 - 2.7e-23 82.3 0.0 3.8e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2781 PF10914.3 AEO70974.1 - 4.8e-34 117.2 8.1 5.5e-34 117.0 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) AAA PF00004.24 AEO70975.1 - 3.6e-17 62.7 0.0 6.2e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO70975.1 - 0.0046 17.0 0.0 0.018 15.1 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 AEO70975.1 - 0.016 14.9 0.0 0.057 13.1 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 AEO70975.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Abhydrolase_3 PF07859.8 AEO70976.1 - 8.3e-55 185.6 0.0 1e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO70976.1 - 3.1e-05 23.7 0.0 4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO70976.1 - 0.0054 15.9 0.0 0.24 10.5 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2424 PF10340.4 AEO70976.1 - 0.025 13.2 0.0 0.037 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Phage_base_V PF04717.7 AEO70976.1 - 0.031 14.2 0.2 0.77 9.7 0.0 2.6 2 0 0 2 2 2 0 Phage-related baseplate assembly protein APH PF01636.18 AEO70977.1 - 1.4e-32 113.3 0.3 2.6e-32 112.4 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2263 PF10021.4 AEO70978.1 - 2.5e-22 79.4 0.0 2.2e-21 76.4 0.0 2.2 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) adh_short PF00106.20 AEO70979.1 - 3.8e-16 59.4 0.0 5.1e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO70979.1 - 6.3e-08 32.6 0.0 7.3e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO70979.1 - 1.1e-06 28.4 0.1 1.3e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 KR domain BTG PF07742.7 AEO70979.1 - 0.029 13.8 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 BTG family RmlD_sub_bind PF04321.12 AEO70979.1 - 0.073 11.9 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Pyridox_oxidase PF01243.15 AEO70980.1 - 2.7e-05 24.1 0.0 6e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase zf-C2H2 PF00096.21 AEO70981.1 - 0.067 13.5 1.2 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type FAD_binding_3 PF01494.14 AEO70982.1 - 8.5e-14 51.3 0.4 1e-12 47.8 0.3 2.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 AEO70982.1 - 0.0028 17.6 0.0 0.008 16.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 AEO70982.1 - 0.029 13.2 0.0 1 8.2 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 AEO70982.1 - 0.072 12.9 0.0 1.8 8.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 7kD_coat PF02495.12 AEO70982.1 - 0.15 11.4 0.0 0.39 10.1 0.0 1.6 1 0 0 1 1 1 0 7kD viral coat protein Glyco_hydro_28 PF00295.12 AEO70983.1 - 3.4e-109 364.7 17.0 3.9e-109 364.5 11.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2111 PF09884.4 AEO70983.1 - 0.056 13.2 0.2 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) SET PF00856.23 AEO70984.1 - 5.8e-07 29.9 0.0 1.1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 SET domain TPR_12 PF13424.1 AEO70984.1 - 0.0053 16.6 0.0 0.03 14.2 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 AEO70984.1 - 0.017 14.7 0.0 0.042 13.4 0.0 1.6 1 0 0 1 1 1 0 TPR repeat FAA_hydrolase PF01557.13 AEO70985.1 - 9.4e-53 178.8 0.0 1.1e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family COesterase PF00135.23 AEO70986.1 - 6.2e-46 157.2 0.6 1.9e-27 96.2 0.1 3.0 1 1 2 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO70986.1 - 1.6e-08 34.4 0.2 2.1e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO70986.1 - 0.0016 18.2 0.1 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO70986.1 - 0.081 12.7 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family GMC_oxred_N PF00732.14 AEO70987.1 - 1.7e-28 99.6 0.0 1.7e-26 93.0 0.0 2.8 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO70987.1 - 1.4e-27 96.7 0.0 2.5e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 AEO70987.1 - 0.001 19.0 0.1 0.0033 17.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO70987.1 - 0.0026 17.7 0.1 0.0094 15.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 AEO70987.1 - 0.0036 16.2 0.1 0.016 14.1 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 AEO70987.1 - 0.0068 15.2 0.8 0.023 13.5 0.1 2.0 1 1 1 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 AEO70987.1 - 0.0074 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO70987.1 - 0.021 13.7 0.0 0.15 10.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AEO70987.1 - 0.037 14.0 0.0 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 AEO70987.1 - 0.24 11.0 0.0 0.44 10.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Bac_luciferase PF00296.15 AEO70988.1 - 8.1e-68 228.7 0.1 1e-67 228.4 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase HET PF06985.6 AEO70989.1 - 8.2e-27 94.0 0.0 1.7e-26 93.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GMC_oxred_C PF05199.8 AEO70990.1 - 2.4e-31 108.9 0.0 4e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 AEO70990.1 - 2.3e-29 102.5 0.0 3.9e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase HD PF01966.17 AEO70991.1 - 0.002 18.1 0.2 0.0032 17.4 0.1 1.3 1 0 0 1 1 1 1 HD domain AA_permease_2 PF13520.1 AEO70992.1 - 1.6e-96 323.4 36.1 2e-96 323.1 25.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO70992.1 - 5.1e-19 67.9 32.5 7.4e-19 67.4 22.5 1.2 1 0 0 1 1 1 1 Amino acid permease Vma12 PF11712.3 AEO70992.1 - 0.3 10.8 0.0 0.3 10.8 0.0 2.5 4 0 0 4 4 4 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PHO4 PF01384.15 AEO70994.1 - 1.2e-92 310.0 0.1 3e-92 308.7 0.1 1.6 1 1 0 1 1 1 1 Phosphate transporter family Syndecan PF01034.15 AEO70994.1 - 0.09 12.4 2.0 0.15 11.7 0.0 2.5 2 0 0 2 2 2 0 Syndecan domain DUF2985 PF11204.3 AEO70995.1 - 8.7e-30 102.3 2.1 3.3e-28 97.2 2.8 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) MatE PF01554.13 AEO70996.1 - 8.1e-43 145.8 36.6 5e-24 84.7 8.2 2.9 2 1 1 3 3 3 2 MatE AA_permease_2 PF13520.1 AEO70998.1 - 6.9e-44 150.0 51.4 8.8e-44 149.6 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO70998.1 - 5.1e-29 100.9 46.6 6.9e-29 100.5 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2490 PF10677.4 AEO70999.1 - 0.056 12.7 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2490) Chitin_bind_3 PF03067.10 AEO71000.1 - 7.7e-09 36.0 0.1 1e-08 35.6 0.1 1.2 1 0 0 1 1 1 1 Chitin binding domain EpsG PF14897.1 AEO71001.1 - 0.044 12.7 2.9 0.059 12.2 2.0 1.1 1 0 0 1 1 1 0 EpsG family DNA_ligase_aden PF01653.13 AEO71001.1 - 0.19 10.6 0.0 6.9 5.5 0.0 2.0 1 1 1 2 2 2 0 NAD-dependent DNA ligase adenylation domain DUF3902 PF13042.1 AEO71001.1 - 0.32 10.2 4.9 0.92 8.7 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3902) Abhydrolase_6 PF12697.2 AEO71002.1 - 1.8e-25 90.1 0.5 3.3e-25 89.3 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO71002.1 - 9.8e-09 35.1 0.0 2.4e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold EthD PF07110.6 AEO71002.1 - 0.00015 22.5 0.1 0.067 14.1 0.0 2.8 2 0 0 2 2 2 1 EthD domain Abhydrolase_5 PF12695.2 AEO71002.1 - 0.00029 20.5 0.0 0.00056 19.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 AEO71002.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Meth_synt_2 PF01717.13 AEO71003.1 - 2.3e-10 39.9 0.0 5.1e-09 35.5 0.0 2.5 2 1 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 AEO71003.1 - 0.00019 20.7 0.1 0.0019 17.5 0.0 2.5 3 1 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain Apyrase PF06079.6 AEO71003.1 - 0.084 12.0 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Apyrase RdRP PF05183.7 AEO71004.1 - 4.7e-160 534.0 0.0 5.9e-160 533.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Smg4_UPF3 PF03467.10 AEO71004.1 - 0.28 11.1 0.0 0.48 10.3 0.0 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family F-box PF00646.28 AEO71005.1 - 4.6e-09 35.7 0.2 1e-08 34.6 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 AEO71005.1 - 6.5e-08 32.1 0.4 1.6e-07 30.9 0.3 1.7 1 0 0 1 1 1 1 F-box-like SdpI PF13630.1 AEO71005.1 - 3.2 7.5 7.8 28 4.5 1.0 2.4 1 1 1 2 2 2 0 SdpI/YhfL protein family Histone PF00125.19 AEO71006.1 - 2.2e-22 78.9 0.1 2.8e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AEO71006.1 - 4.7e-05 23.3 0.0 6.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.17 AEO71007.1 - 1.4e-10 40.7 0.0 2.6e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 AEO71007.1 - 6.3e-08 32.4 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO71007.1 - 1.7e-07 30.7 0.0 2.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO71007.1 - 2.1e-05 24.2 0.0 3.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 AEO71007.1 - 0.029 14.3 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 Inositol_P PF00459.20 AEO71009.1 - 3.9e-35 121.4 0.2 2.4e-34 118.8 0.2 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family DUF1996 PF09362.5 AEO71010.1 - 7.7e-78 261.3 1.2 9.6e-78 261.0 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HIPIP PF01355.12 AEO71010.1 - 0.19 11.8 2.6 8.3 6.6 0.0 2.6 2 0 0 2 2 2 0 High potential iron-sulfur protein Na_Ca_ex PF01699.19 AEO71011.1 - 3.6e-33 114.1 20.7 3.2e-20 72.1 5.7 3.5 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 AEO71011.1 - 1.4e-14 54.2 14.0 1.4e-14 54.2 9.7 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF307) AAA PF00004.24 AEO71012.1 - 5.1e-44 149.6 0.0 8.5e-44 148.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AEO71012.1 - 3.1e-08 33.4 0.0 7.5e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AEO71012.1 - 1.2e-07 31.8 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 AEO71012.1 - 3.2e-06 27.2 0.0 1e-05 25.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AEO71012.1 - 4.6e-06 26.8 0.1 0.00025 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO71012.1 - 6.1e-05 23.8 0.0 0.00015 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AEO71012.1 - 7.6e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AEO71012.1 - 0.00014 21.5 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 AEO71012.1 - 0.00042 19.7 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 AEO71012.1 - 0.00089 18.0 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 AEO71012.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AEO71012.1 - 0.0018 18.2 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 AEO71012.1 - 0.0022 17.5 0.0 0.0074 15.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 AEO71012.1 - 0.0024 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 AEO71012.1 - 0.0037 17.2 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO71012.1 - 0.0068 16.7 0.0 0.028 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 AEO71012.1 - 0.0069 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 AEO71012.1 - 0.0074 15.4 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 AEO71012.1 - 0.017 14.5 0.1 0.075 12.4 0.0 2.0 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.8 AEO71012.1 - 0.018 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 AEO71012.1 - 0.019 14.4 0.0 0.085 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain PhoH PF02562.11 AEO71012.1 - 0.019 14.2 0.0 0.07 12.3 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 AEO71012.1 - 0.021 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AEO71012.1 - 0.028 14.5 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2072 PF09845.4 AEO71012.1 - 0.042 13.7 0.1 0.092 12.6 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Sigma54_activ_2 PF14532.1 AEO71012.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Histone PF00125.19 AEO71012.1 - 0.046 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Parvo_NS1 PF01057.12 AEO71012.1 - 0.051 12.4 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 AEO71012.1 - 0.076 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 AEO71012.1 - 0.099 12.2 0.0 0.53 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Y_phosphatase PF00102.22 AEO71013.1 - 8.9e-55 185.5 0.0 1.2e-30 106.5 0.0 4.1 4 0 0 4 4 4 4 Protein-tyrosine phosphatase Rhodanese PF00581.15 AEO71013.1 - 1.5e-11 44.6 0.0 4.5e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain HTH_29 PF13551.1 AEO71013.1 - 0.024 14.7 0.2 0.45 10.6 0.1 2.6 2 0 0 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.1 AEO71013.1 - 0.032 14.2 0.1 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Y_phosphatase3 PF13350.1 AEO71013.1 - 0.037 14.2 0.1 0.084 13.1 0.1 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 AEO71013.1 - 0.11 12.0 0.1 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain BC10 PF06726.7 AEO71014.1 - 1e-16 60.6 12.0 1.8e-16 59.9 8.3 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 RHD3 PF05879.7 AEO71015.1 - 0.21 9.4 6.1 0.51 8.1 4.2 1.5 1 1 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) COG2 PF06148.6 AEO71015.1 - 4.8 7.0 10.2 0.11 12.3 0.9 2.7 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Zip PF02535.17 AEO71015.1 - 5.1 6.0 9.0 11 4.9 6.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1515 PF07439.6 AEO71015.1 - 5.7 6.7 6.2 3.7 7.3 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) AAA PF00004.24 AEO71016.1 - 2.7e-19 69.6 0.0 4.5e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AEO71016.1 - 6.3e-05 22.7 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AEO71016.1 - 0.00016 21.7 0.0 0.00043 20.3 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_17 PF13207.1 AEO71016.1 - 0.0003 21.6 0.0 0.001 19.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO71016.1 - 0.0003 20.4 0.1 0.00089 18.9 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 AEO71016.1 - 0.0012 18.9 0.0 0.0069 16.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zot PF05707.7 AEO71016.1 - 0.0017 17.8 0.1 0.04 13.3 0.0 2.4 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.12 AEO71016.1 - 0.0035 16.7 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 AEO71016.1 - 0.0037 17.5 0.0 0.0099 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 AEO71016.1 - 0.0051 16.7 0.0 0.0096 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_30 PF13604.1 AEO71016.1 - 0.0055 16.3 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AEO71016.1 - 0.0063 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 AEO71016.1 - 0.016 14.3 0.1 0.041 12.9 0.1 1.6 1 1 0 1 1 1 0 KaiC Mg_chelatase PF01078.16 AEO71016.1 - 0.02 14.0 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 AEO71016.1 - 0.025 13.9 0.0 0.066 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AEO71016.1 - 0.029 14.3 0.1 0.15 11.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 AEO71016.1 - 0.044 13.6 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AEO71016.1 - 0.086 11.9 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.21 AEO71016.1 - 0.1 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.8 AEO71016.1 - 0.14 10.7 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus PhoH PF02562.11 AEO71016.1 - 0.16 11.1 0.2 0.4 9.8 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein RuvB_N PF05496.7 AEO71016.1 - 0.17 10.9 0.1 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF4306 PF14154.1 AEO71017.1 - 0.24 11.3 4.1 13 5.8 0.2 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4306) RVT_1 PF00078.22 AEO71018.1 - 0.1 11.9 0.6 0.1 11.9 0.4 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Bunya_G2 PF03563.8 AEO71018.1 - 1.3 7.7 4.4 1.5 7.6 3.1 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Ribosomal_S19 PF00203.16 AEO71019.1 - 1.5e-23 82.2 0.1 2.2e-23 81.6 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.8 AEO71020.1 - 1.3e-17 63.3 0.0 1.8e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 AEO71020.1 - 0.076 12.7 0.1 8.3 6.2 0.0 2.1 2 0 0 2 2 2 0 Bromodomain associated Chisel PF15355.1 AEO71020.1 - 2.2 8.3 4.0 0.75 9.8 0.5 1.8 2 0 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel Mre11_DNA_bind PF04152.9 AEO71021.1 - 2.7e-59 199.9 0.7 2.7e-59 199.9 0.5 1.8 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 AEO71021.1 - 3.9e-26 91.7 2.1 5.6e-26 91.1 1.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AEO71021.1 - 3.1e-06 27.1 0.1 8e-06 25.7 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain APC10 PF03256.11 AEO71022.1 - 2.2e-44 151.3 0.0 2.9e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 AEO71022.1 - 0.048 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain PITH PF06201.8 AEO71022.1 - 0.13 12.0 0.0 3.6 7.3 0.0 2.2 2 0 0 2 2 2 0 PITH domain CTP_transf_2 PF01467.21 AEO71023.1 - 0.0051 16.8 0.1 0.018 15.0 0.0 1.8 2 1 0 2 2 2 1 Cytidylyltransferase PTR2 PF00854.16 AEO71024.1 - 1.8e-26 92.8 2.5 1.2e-24 86.8 0.7 2.6 2 1 0 2 2 2 1 POT family Asp PF00026.18 AEO71025.1 - 7.9e-78 261.8 3.0 9.4e-78 261.6 2.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO71025.1 - 2.3e-10 40.6 0.0 2.3e-08 34.1 0.0 3.0 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO71025.1 - 1.4e-05 25.5 0.1 0.051 14.0 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease Striatin PF08232.7 AEO71026.1 - 5.1e-35 120.7 1.2 5.1e-35 120.7 0.9 2.3 2 0 0 2 2 2 1 Striatin family WD40 PF00400.27 AEO71026.1 - 1.2e-32 110.6 16.6 7.7e-08 31.9 0.0 7.5 7 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 AEO71026.1 - 0.093 12.4 0.0 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 AEO71026.1 - 0.18 10.0 0.0 0.34 9.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain XPA_C PF05181.7 AEO71027.1 - 3.6e-29 100.1 3.9 3.6e-29 100.1 2.7 2.1 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.13 AEO71027.1 - 1.7 8.4 9.8 0.26 10.9 3.8 1.9 2 0 0 2 2 2 0 XPA protein N-terminal Pho88 PF10032.4 AEO71028.1 - 5.4e-78 260.6 0.0 6e-78 260.4 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) GMC_oxred_N PF00732.14 AEO71029.1 - 1.6e-28 99.7 0.0 2.6e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO71029.1 - 2.1e-21 76.7 0.1 3.7e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 AEO71029.1 - 1.2e-09 37.5 0.1 0.00012 21.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 AEO71029.1 - 1.5e-07 30.6 0.1 0.00014 20.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AEO71029.1 - 2.8e-05 24.0 0.0 5.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO71029.1 - 4.3e-05 23.4 0.1 0.00018 21.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 AEO71029.1 - 0.0015 17.6 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 AEO71029.1 - 0.0025 16.9 0.0 0.17 10.9 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AEO71029.1 - 0.0047 15.4 0.0 0.0067 14.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 AEO71029.1 - 0.0054 16.8 0.0 0.03 14.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO71029.1 - 0.027 14.8 0.0 0.65 10.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO71029.1 - 0.081 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Glyco_hydro_61 PF03443.9 AEO71030.1 - 5.3e-53 180.0 0.1 6.2e-53 179.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 AEO71031.1 - 8.1e-54 182.7 0.6 9.3e-54 182.5 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HCV_NS4a PF01006.15 AEO71031.1 - 0.0044 16.5 1.0 0.019 14.5 0.2 2.4 2 1 0 2 2 2 1 Hepatitis C virus non-structural protein NS4a NPCBM_assoc PF10633.4 AEO71031.1 - 0.018 15.0 0.3 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF2945 PF11160.3 AEO71032.1 - 5.7e-22 77.3 0.1 6.4e-22 77.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) SpoIIIAH PF12685.2 AEO71034.1 - 0.079 12.4 0.2 0.1 12.0 0.1 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein Sporozoite_P67 PF05642.6 AEO71034.1 - 2 6.1 19.4 2.4 5.9 13.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2217 PF10265.4 AEO71034.1 - 7 5.2 7.5 7.5 5.1 5.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SSP160 PF06933.6 AEO71034.1 - 7.2 4.4 26.4 8.9 4.1 18.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3633 PF12315.3 AEO71034.1 - 7.2 5.8 5.5 9.5 5.4 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) TPR_12 PF13424.1 AEO71035.1 - 6.7e-13 48.3 0.2 2.9e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 AEO71035.1 - 0.00038 20.2 0.6 1.6 8.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AEO71035.1 - 0.0026 18.2 2.2 2.1 9.1 0.1 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat Clr5 PF14420.1 AEO71035.1 - 0.02 14.8 0.1 0.052 13.4 0.1 1.7 1 0 0 1 1 1 0 Clr5 domain TPR_11 PF13414.1 AEO71035.1 - 0.023 14.3 0.0 0.78 9.4 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_4 PF07721.9 AEO71035.1 - 0.044 14.2 1.9 0.33 11.4 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 AEO71035.1 - 0.045 13.6 0.4 0.57 10.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 AEO71035.1 - 0.05 14.3 0.3 6.6 7.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 AEO71035.1 - 0.053 13.3 0.1 4.4 7.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PetN PF03742.9 AEO71035.1 - 0.16 11.5 0.5 0.34 10.5 0.3 1.5 1 0 0 1 1 1 0 PetN DctQ PF04290.7 AEO71036.1 - 2.6 7.8 6.6 0.4 10.4 0.1 2.3 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF161 PF02588.10 AEO71036.1 - 3.7 7.9 6.2 7.5 6.9 0.8 2.8 1 1 1 2 2 2 0 Uncharacterized BCR, YitT family COG1284 HET PF06985.6 AEO71037.1 - 2e-19 70.1 0.0 3.6e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Amidohydro_1 PF01979.15 AEO71038.1 - 8.6e-34 117.6 0.1 1.2e-33 117.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 AEO71038.1 - 2.2e-09 37.0 0.9 1.9e-06 27.3 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 AEO71038.1 - 1.1e-08 35.4 2.9 8.5e-08 32.5 2.0 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 AEO71038.1 - 5.1e-05 23.0 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 AEO71038.1 - 0.0078 15.1 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase Med18 PF09637.5 AEO71039.1 - 0.00095 18.7 0.1 0.0011 18.6 0.1 1.0 1 0 0 1 1 1 1 Med18 protein Fructosamin_kin PF03881.9 AEO71040.1 - 6.8e-69 232.0 0.0 7.3e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 AEO71040.1 - 8.1e-06 25.7 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 AEO71041.1 - 1.3e-29 103.1 0.0 3.1e-29 101.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71041.1 - 8.8e-13 47.9 0.0 1.5e-12 47.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO71041.1 - 0.00053 19.7 0.8 0.0012 18.6 0.3 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 AEO71041.1 - 0.024 13.4 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RHD3 PF05879.7 AEO71042.1 - 0 1084.2 0.0 0 1083.9 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 AEO71042.1 - 2.1e-07 30.3 0.1 3.5e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 AEO71042.1 - 1.7e-06 27.9 0.0 3.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 AEO71042.1 - 0.0001 22.2 0.0 0.00032 20.6 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 AEO71042.1 - 0.00011 22.1 0.4 0.00058 19.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 AEO71042.1 - 0.0017 18.8 0.1 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 AEO71042.1 - 0.021 13.8 0.1 0.04 12.9 0.1 1.4 1 0 0 1 1 1 0 Septin Rota_NSP3 PF01665.11 AEO71042.1 - 0.15 10.9 1.6 0.55 9.1 0.2 2.2 2 0 0 2 2 2 0 Rotavirus non-structural protein NSP3 RNase_HII PF01351.13 AEO71043.1 - 1.3e-42 145.7 0.0 9.1e-39 133.1 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease HII Mif2_N PF15624.1 AEO71044.1 - 4.1e-40 137.5 0.5 4.1e-40 137.5 0.3 3.8 3 1 1 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 AEO71044.1 - 9.5e-33 112.0 0.5 1.5e-32 111.4 0.3 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 AEO71044.1 - 0.0002 20.7 0.0 0.00053 19.4 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 AEO71044.1 - 0.0053 16.3 1.0 0.063 12.8 0.0 2.9 3 1 0 3 3 3 1 Cupin DDE_5 PF13546.1 AEO71044.1 - 6.4 5.5 7.0 3.5 6.4 0.9 2.3 2 0 0 2 2 2 0 DDE superfamily endonuclease RNA12 PF10443.4 AEO71045.1 - 2.5e-161 536.9 0.1 1.1e-160 534.8 0.0 1.8 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.17 AEO71045.1 - 2e-05 24.1 0.0 7.1e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO71045.1 - 0.0065 16.2 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 AEO71045.1 - 0.0089 15.7 0.0 0.033 13.8 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase DUF2487 PF10673.4 AEO71045.1 - 0.016 15.0 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) RRM_6 PF14259.1 AEO71045.1 - 0.03 14.3 0.0 0.084 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3128 PF11326.3 AEO71046.1 - 5.8e-27 93.6 0.5 1.2e-26 92.6 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) ORC6 PF05460.8 AEO71046.1 - 0.0022 17.1 15.5 0.0033 16.5 10.7 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) HSP70 PF00012.15 AEO71047.1 - 2.7e-272 904.0 4.1 3.1e-272 903.9 2.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AEO71047.1 - 4.6e-17 61.6 0.0 7.3e-16 57.6 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 AEO71047.1 - 0.0029 17.2 0.0 0.0077 15.8 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 AEO71047.1 - 0.012 14.7 0.1 0.053 12.6 0.0 2.0 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.6 AEO71047.1 - 0.044 12.7 0.0 0.092 11.6 0.0 1.5 1 0 0 1 1 1 0 StbA protein FtsA PF14450.1 AEO71047.1 - 0.27 11.0 2.1 12 5.7 1.5 3.1 1 1 0 1 1 1 0 Cell division protein FtsA DUF4404 PF14357.1 AEO71047.1 - 0.89 10.0 6.9 0.86 10.0 1.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Pkinase PF00069.20 AEO71048.1 - 1.6e-28 99.6 0.0 3.4e-28 98.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71048.1 - 1.1e-07 31.2 0.0 1.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO71048.1 - 0.023 13.7 0.1 0.049 12.6 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 AEO71048.1 - 0.049 12.4 0.1 0.072 11.9 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 DLH PF01738.13 AEO71049.1 - 9.2e-28 97.0 0.0 1.2e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AEO71049.1 - 3.8e-07 29.9 0.1 5.5e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO71049.1 - 2.5e-05 24.2 0.4 0.00028 20.8 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 AEO71049.1 - 0.00015 21.5 0.0 0.0012 18.5 0.0 1.9 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 AEO71049.1 - 0.0078 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 AEO71049.1 - 0.021 13.3 0.0 0.043 12.3 0.0 1.5 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) MS_channel PF00924.13 AEO71050.1 - 3e-21 75.7 2.2 5.2e-21 74.9 1.5 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.1 AEO71050.1 - 0.0088 16.1 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 AEO71050.1 - 0.022 14.6 0.1 0.064 13.1 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.27 AEO71050.1 - 0.023 13.9 0.1 0.057 12.7 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.1 AEO71050.1 - 0.033 13.5 0.0 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 EF hand ODV-E18 PF10717.4 AEO71050.1 - 0.12 11.8 0.7 0.4 10.1 0.5 1.9 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 tRNA-synt_2b PF00587.20 AEO71051.1 - 3.6e-21 75.5 0.0 4.8e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 AEO71051.1 - 5.3e-12 45.7 2.4 2.5e-11 43.5 1.7 1.9 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Prp19 PF08606.6 AEO71051.1 - 0.088 12.5 0.3 0.26 11.0 0.1 1.9 2 0 0 2 2 2 0 Prp19/Pso4-like Ala_racemase_N PF01168.15 AEO71053.1 - 2.4e-44 151.5 0.0 2.9e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain F-box-like PF12937.2 AEO71054.1 - 3e-06 26.8 0.6 7.9e-06 25.4 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO71054.1 - 1.5 8.5 8.5 0.13 11.9 0.7 3.0 3 1 0 3 3 3 0 F-box domain Mo25 PF08569.6 AEO71055.1 - 8.1e-128 426.1 0.0 9.1e-128 425.9 0.0 1.0 1 0 0 1 1 1 1 Mo25-like GspL_C PF12693.2 AEO71055.1 - 0.059 13.1 0.4 0.097 12.4 0.3 1.2 1 0 0 1 1 1 0 GspL periplasmic domain KOW PF00467.24 AEO71056.1 - 1.4e-07 30.9 1.6 4.7e-07 29.2 1.1 1.9 2 0 0 2 2 2 1 KOW motif Sfi1 PF08457.5 AEO71057.1 - 2e-142 475.5 91.1 1.9e-137 459.1 58.3 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein tRNA-synt_1 PF00133.17 AEO71058.1 - 5.9e-224 744.5 0.0 9.4e-224 743.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AEO71058.1 - 1.4e-26 93.0 0.0 4.1e-26 91.5 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AEO71058.1 - 1.1e-19 70.3 0.4 2.2e-08 33.1 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 AEO71058.1 - 0.024 13.7 0.0 0.17 11.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain APC_CDC26 PF10471.4 AEO71061.1 - 0.057 14.1 0.7 0.15 12.8 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Pkinase PF00069.20 AEO71062.1 - 6.7e-70 235.1 0.0 8.9e-70 234.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71062.1 - 9.3e-35 119.9 0.0 1.5e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO71062.1 - 5.7e-05 22.2 0.4 0.0045 15.9 0.0 2.7 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 AEO71062.1 - 0.00031 19.8 0.0 0.00051 19.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO71062.1 - 0.0026 17.5 0.1 0.0096 15.6 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family SWIB PF02201.13 AEO71063.1 - 3.1e-13 49.2 0.0 6e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain XPG_I PF00867.13 AEO71064.1 - 1.1e-24 86.2 0.0 2.6e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 XPG I-region Actin PF00022.14 AEO71065.1 - 1.2e-16 60.1 0.0 3.5e-15 55.3 0.0 2.7 2 1 0 2 2 2 2 Actin SR-25 PF10500.4 AEO71067.1 - 0.00032 20.2 15.8 0.00039 19.9 6.6 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Apt1 PF10351.4 AEO71067.1 - 2.9 6.6 7.4 4.2 6.1 5.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Herpes_DNAp_acc PF04929.7 AEO71067.1 - 3.7 6.4 14.0 5.2 5.9 9.7 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Rrn6 PF10214.4 AEO71067.1 - 4 5.4 15.1 5.4 4.9 10.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Abp2 PF09441.5 AEO71068.1 - 2.1e-90 301.3 0.0 3.2e-90 300.7 0.0 1.2 1 0 0 1 1 1 1 ARS binding protein 2 Spore_coat_CotO PF14153.1 AEO71068.1 - 2.9 7.3 5.4 3.2 7.1 1.8 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Mito_carr PF00153.22 AEO71069.1 - 1.1e-54 182.1 1.0 5.3e-18 64.5 0.4 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 AEO71069.1 - 0.007 16.1 0.1 0.022 14.5 0.1 1.9 2 0 0 2 2 2 1 UcrQ family Sas10 PF09368.5 AEO71069.1 - 0.13 12.4 0.4 0.28 11.3 0.3 1.5 1 0 0 1 1 1 0 Sas10 C-terminal domain Mak10 PF04112.8 AEO71070.1 - 3.6e-20 71.8 0.0 3e-17 62.3 0.0 2.4 1 1 1 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.8 AEO71071.1 - 5.8e-21 73.7 2.7 5.8e-21 73.7 1.9 2.2 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Peptidase_M16 PF00675.15 AEO71071.1 - 3.3e-20 72.3 0.0 6.7e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 AEO71071.1 - 2.6e-14 53.3 0.0 9.4e-14 51.4 0.0 2.0 3 0 0 3 3 3 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.8 AEO71072.1 - 2.8e-67 226.9 0.0 5.4e-67 226.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 AEO71072.1 - 5e-06 26.2 0.4 0.012 15.4 0.0 3.4 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 AEO71072.1 - 0.0013 18.1 0.8 0.21 11.1 0.0 4.2 4 1 0 4 4 4 1 TFIIE alpha subunit DUF4611 PF15387.1 AEO71072.1 - 0.43 10.7 7.7 7.1 6.8 3.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 AEO71072.1 - 1.5 8.3 10.3 2.9 7.4 2.9 3.2 3 0 0 3 3 3 0 Sigma-70, non-essential region Mito_carr PF00153.22 AEO71073.1 - 4.8e-28 96.7 0.2 5.4e-14 51.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR_4 PF12799.2 AEO71074.1 - 0.0026 17.3 3.2 18 5.0 0.2 5.4 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 AEO71074.1 - 0.063 13.3 0.1 52 4.3 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat DUF4614 PF15391.1 AEO71074.1 - 0.13 12.0 1.6 0.22 11.3 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) LRR_1 PF00560.28 AEO71074.1 - 0.52 10.5 2.2 24 5.4 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat zf-H2C2_5 PF13909.1 AEO71075.1 - 0.0069 16.5 2.6 0.0069 16.5 1.8 2.9 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 AEO71075.1 - 0.023 14.9 15.4 0.15 12.4 2.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO71075.1 - 0.14 12.5 15.3 0.061 13.6 2.7 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 AEO71075.1 - 0.54 10.4 6.1 0.92 9.6 4.3 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Hexapep PF00132.19 AEO71076.1 - 3.2e-08 32.7 0.6 0.0048 16.3 0.0 2.9 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 AEO71076.1 - 2e-05 24.7 0.0 4.8e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 AEO71076.1 - 7.6e-05 22.1 0.0 0.00023 20.5 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep_2 PF14602.1 AEO71076.1 - 0.062 12.8 5.8 1.2 8.8 1.9 3.1 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 AEO71076.1 - 0.17 10.3 0.9 0.56 8.7 0.6 1.7 1 1 0 1 1 1 0 L-fucokinase Spt20 PF12090.3 AEO71078.1 - 1.1e-47 161.7 0.0 1.1e-47 161.7 0.0 6.7 3 2 1 5 5 5 1 Spt20 family ATG27 PF09451.5 AEO71079.1 - 1.1e-71 241.1 0.3 1.1e-70 238.0 0.2 2.0 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 AEO71079.1 - 0.0061 16.3 0.1 0.34 10.6 0.0 2.8 3 0 0 3 3 3 1 Cation-independent mannose-6-phosphate receptor repeat SSI PF00720.12 AEO71079.1 - 0.013 15.4 0.8 0.45 10.4 0.4 2.4 2 0 0 2 2 2 0 Subtilisin inhibitor-like SRP-alpha_N PF04086.8 AEO71079.1 - 0.28 10.5 4.6 0.36 10.1 3.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ECH PF00378.15 AEO71080.1 - 5.3e-17 61.7 0.0 7.3e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 AEO71080.1 - 0.0078 16.0 0.0 0.91 9.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 IPK PF03770.11 AEO71081.1 - 1.1e-55 188.3 0.0 3.8e-55 186.6 0.0 1.8 2 0 0 2 2 2 1 Inositol polyphosphate kinase Pam17 PF08566.5 AEO71081.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 DUF1676 PF07898.8 AEO71082.1 - 0.067 13.5 0.9 0.25 11.6 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF3525 PF12039.3 AEO71082.1 - 0.24 9.8 0.3 0.39 9.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) LRR_4 PF12799.2 AEO71083.1 - 1.1e-35 120.5 24.3 2.8e-09 36.3 0.5 8.3 7 1 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO71083.1 - 2.6e-22 78.3 33.5 3.3e-10 39.5 0.2 6.9 4 1 4 9 9 9 6 Leucine rich repeat LRR_1 PF00560.28 AEO71083.1 - 7.1e-13 46.6 26.3 0.48 10.6 0.1 11.8 10 2 0 10 10 10 5 Leucine Rich Repeat LRR_6 PF13516.1 AEO71083.1 - 1.4e-11 43.1 20.6 0.74 10.0 0.1 9.9 9 2 2 11 11 11 5 Leucine Rich repeat LRR_7 PF13504.1 AEO71083.1 - 2.1e-09 36.0 35.4 1.2 9.6 0.0 11.7 11 1 1 12 12 12 4 Leucine rich repeat LRR_9 PF14580.1 AEO71083.1 - 2.6e-09 36.8 8.6 0.0043 16.6 0.1 4.8 3 1 2 5 5 5 3 Leucine-rich repeat PRP38 PF03371.10 AEO71083.1 - 0.44 10.1 0.0 0.84 9.2 0.0 1.4 1 0 0 1 1 1 0 PRP38 family VWA_2 PF13519.1 AEO71084.1 - 3.4e-05 24.0 0.0 5.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 AEO71084.1 - 0.0038 16.9 0.0 0.0057 16.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 AEO71084.1 - 0.0083 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Aminotran_1_2 PF00155.16 AEO71085.1 - 1.7e-35 122.6 0.0 2e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AEO71085.1 - 0.087 11.9 0.0 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 Beta-eliminating lyase bZIP_2 PF07716.10 AEO71088.1 - 1.4e-12 47.2 9.4 2.9e-12 46.2 6.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 AEO71088.1 - 6.7e-05 22.7 9.1 6.7e-05 22.7 6.3 1.8 2 1 0 2 2 2 1 bZIP transcription factor XhlA PF10779.4 AEO71088.1 - 0.017 14.9 2.2 0.035 14.0 1.5 1.5 1 0 0 1 1 1 0 Haemolysin XhlA TSC22 PF01166.13 AEO71088.1 - 0.048 13.6 0.2 0.14 12.1 0.1 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family bZIP_Maf PF03131.12 AEO71088.1 - 0.17 12.1 4.6 0.36 11.1 3.2 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor UreE_C PF05194.7 AEO71088.1 - 0.41 10.7 3.1 3.7 7.6 1.3 2.5 2 0 0 2 2 2 0 UreE urease accessory protein, C-terminal domain Pkinase PF00069.20 AEO71089.1 - 1.9e-46 158.3 0.0 2.9e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71089.1 - 2.8e-24 85.5 0.0 3.7e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 AEO71089.1 - 2.5e-08 33.8 0.0 5.3e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 AEO71089.1 - 3.6e-05 22.8 0.0 7.8e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO71089.1 - 0.028 14.1 0.9 0.066 12.9 0.0 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family CENP-N PF05238.8 AEO71092.1 - 1.4e-120 403.0 0.0 1.8e-120 402.7 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like TatD_DNase PF01026.16 AEO71093.1 - 2e-43 148.4 0.0 1.5e-33 116.0 0.0 2.8 2 1 0 2 2 2 2 TatD related DNase MelC1 PF06236.6 AEO71093.1 - 6.4 6.7 8.4 0.7 9.8 1.8 2.2 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 Ribonuc_red_lgC PF02867.10 AEO71096.1 - 1.2e-220 733.6 0.0 1.6e-220 733.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 AEO71096.1 - 1.9e-23 82.0 0.0 5.7e-23 80.5 0.0 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 AEO71096.1 - 2.1e-17 63.3 0.1 7.2e-17 61.6 0.0 2.0 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 AEO71096.1 - 0.11 10.5 0.0 0.18 9.8 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase CFEM PF05730.6 AEO71097.1 - 1.2e-13 50.6 4.4 2e-13 49.9 3.1 1.4 1 0 0 1 1 1 1 CFEM domain Pkinase PF00069.20 AEO71098.1 - 8.8e-53 179.0 0.0 1.4e-37 129.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71098.1 - 6.2e-20 71.3 0.1 3.4e-18 65.6 0.1 3.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO71098.1 - 7.8e-05 21.7 0.0 0.0002 20.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 AEO71098.1 - 0.0035 17.1 0.7 0.0087 15.8 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Glycos_transf_1 PF00534.15 AEO71099.1 - 3.1e-32 111.3 0.0 1.8e-31 108.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 AEO71099.1 - 1.8e-09 37.5 0.4 9.1e-09 35.2 0.3 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 AEO71099.1 - 3.8e-09 36.8 9.6 3.8e-09 36.8 6.6 3.0 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 AEO71099.1 - 5.4e-08 33.0 0.6 3.9e-06 27.0 0.1 3.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AEO71099.1 - 5.1e-07 29.8 0.0 1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 TBPIP PF07106.8 AEO71100.1 - 0.016 14.8 0.6 0.016 14.8 0.4 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ThiS PF02597.15 AEO71100.1 - 0.091 13.1 0.4 0.19 12.1 0.3 1.6 1 0 0 1 1 1 0 ThiS family Filament PF00038.16 AEO71100.1 - 0.1 12.0 9.3 0.018 14.5 2.7 2.0 2 0 0 2 2 2 0 Intermediate filament protein Macoilin PF09726.4 AEO71100.1 - 0.61 8.2 7.5 0.027 12.7 1.1 1.6 2 0 0 2 2 2 0 Transmembrane protein IncA PF04156.9 AEO71100.1 - 0.89 9.1 6.2 2 7.9 4.3 1.5 1 0 0 1 1 1 0 IncA protein CENP-Q PF13094.1 AEO71100.1 - 3.2 7.7 12.5 0.19 11.7 4.5 1.9 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_TATA_bd PF12325.3 AEO71100.1 - 4 7.1 13.8 0.29 10.8 1.4 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Mnd1 PF03962.10 AEO71100.1 - 5.1 6.7 11.4 1.1 8.8 4.2 2.0 2 0 0 2 2 2 0 Mnd1 family DUF904 PF06005.7 AEO71100.1 - 8.4 6.7 9.1 0.37 11.1 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF904) RRM_1 PF00076.17 AEO71101.1 - 3.4e-42 141.9 1.6 8e-19 67.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO71101.1 - 3.8e-33 113.2 0.3 1.1e-17 63.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 AEO71101.1 - 2.4e-30 104.6 0.2 5.2e-30 103.5 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 AEO71101.1 - 1.2e-20 73.1 0.0 1.8e-08 34.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AEO71101.1 - 0.0071 16.1 1.0 0.17 11.7 0.0 2.9 3 1 0 3 3 3 1 RNA binding motif Cyt-b5 PF00173.23 AEO71102.1 - 2e-19 69.1 0.4 1e-18 66.9 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 AEO71102.1 - 6.5e-09 36.1 24.6 1.6e-08 34.9 15.8 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.1 AEO71102.1 - 0.049 13.2 0.9 0.13 11.8 0.1 2.1 2 0 0 2 2 2 0 Cytochrome oxidase c assembly LrgB PF04172.11 AEO71102.1 - 0.16 11.1 1.8 1.1 8.4 0.1 2.1 2 0 0 2 2 2 0 LrgB-like family Het-C PF07217.6 AEO71103.1 - 1.1e-290 965.0 0.0 1.4e-290 964.8 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C TctA PF01970.11 AEO71103.1 - 0.12 10.7 0.2 0.22 9.8 0.2 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family PP2C PF00481.16 AEO71104.1 - 1.4e-35 122.9 0.0 1e-29 103.7 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SR-25 PF10500.4 AEO71104.1 - 1.1 8.7 7.2 1.8 7.9 5.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MIP-T3 PF10243.4 AEO71104.1 - 2.5 6.4 4.6 3.7 5.9 3.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 BTB PF00651.26 AEO71105.1 - 0.00036 20.4 0.8 0.019 14.9 0.0 2.7 3 0 0 3 3 3 1 BTB/POZ domain ChaC PF04752.7 AEO71105.1 - 0.06 13.2 0.2 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 ChaC-like protein FTR1 PF03239.9 AEO71106.1 - 1.6e-79 267.0 9.7 1.8e-79 266.8 6.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF2232 PF09991.4 AEO71106.1 - 0.0023 16.9 4.3 0.0023 16.9 2.9 2.6 2 1 0 2 2 2 1 Predicted membrane protein (DUF2232) DUF4231 PF14015.1 AEO71106.1 - 0.028 14.4 1.0 0.028 14.4 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF3112 PF11309.3 AEO71106.1 - 0.057 13.2 9.0 0.18 11.6 6.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) YibE_F PF07907.6 AEO71106.1 - 1.8 7.6 11.1 0.15 11.2 1.8 2.3 2 0 0 2 2 2 0 YibE/F-like protein PepSY_TM_3 PF13706.1 AEO71106.1 - 8.3 5.9 13.3 0.58 9.6 4.9 2.4 2 0 0 2 2 2 0 PepSY-associated TM helix Cu-oxidase_3 PF07732.10 AEO71107.1 - 2.7e-46 156.1 4.6 8.8e-43 144.7 0.1 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 AEO71107.1 - 8.7e-43 145.1 3.1 2.3e-36 124.3 0.2 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 AEO71107.1 - 1.6e-40 138.6 0.1 1e-34 119.7 0.0 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 AEO71107.1 - 0.0018 18.1 0.0 11 5.9 0.0 3.7 3 1 0 3 3 3 2 Cupredoxin-like domain CDP-OH_P_transf PF01066.16 AEO71108.1 - 2.7e-16 59.7 1.6 2.7e-16 59.7 1.1 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase OMPdecase PF00215.19 AEO71109.1 - 1.1e-95 319.3 0.2 1.5e-95 318.9 0.2 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Na_trans_assoc PF06512.8 AEO71109.1 - 0.1 12.5 3.2 0.14 12.0 2.2 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated eIF-3_zeta PF05091.7 AEO71109.1 - 0.16 10.5 4.4 0.23 10.0 3.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Fungal_trans PF04082.13 AEO71110.1 - 5.3e-10 38.6 0.0 7.6e-09 34.8 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO71110.1 - 0.0049 16.7 2.7 0.0083 16.0 1.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Disintegrin PF00200.18 AEO71110.1 - 0.29 11.3 2.8 0.53 10.5 1.9 1.3 1 0 0 1 1 1 0 Disintegrin TRF PF08558.5 AEO71112.1 - 1.5e-51 175.1 0.0 2.3e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 AEO71112.1 - 6.2e-06 26.1 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO71112.1 - 0.019 15.0 0.0 0.043 13.9 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Aldedh PF00171.17 AEO71113.1 - 1.1e-190 633.8 0.1 1.2e-190 633.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HALZ PF02183.13 AEO71114.1 - 6.4e-05 22.5 21.3 0.066 12.9 0.3 4.8 5 0 0 5 5 5 2 Homeobox associated leucine zipper DUF812 PF05667.6 AEO71114.1 - 0.00083 17.9 4.8 0.00099 17.7 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) TMF_DNA_bd PF12329.3 AEO71114.1 - 0.0013 18.4 2.8 0.0013 18.4 1.9 3.1 3 0 0 3 3 3 1 TATA element modulatory factor 1 DNA binding Cep57_CLD_2 PF14197.1 AEO71114.1 - 0.0031 17.4 7.1 0.0031 17.4 4.9 3.2 2 1 0 2 2 2 1 Centrosome localisation domain of PPC89 CALCOCO1 PF07888.6 AEO71114.1 - 0.0032 15.8 5.9 0.0032 15.8 4.1 1.9 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like APG6 PF04111.7 AEO71114.1 - 0.0057 15.7 14.7 0.0076 15.3 10.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 bZIP_1 PF00170.16 AEO71114.1 - 0.0068 16.3 17.3 0.15 12.0 1.6 3.7 2 1 0 3 3 3 1 bZIP transcription factor Cep57_CLD PF14073.1 AEO71114.1 - 0.0082 15.9 15.0 0.015 15.1 10.4 1.5 1 1 0 1 1 1 1 Centrosome localisation domain of Cep57 DUF972 PF06156.8 AEO71114.1 - 0.017 15.4 14.0 0.63 10.4 1.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF4201 PF13870.1 AEO71114.1 - 0.019 14.3 15.7 0.072 12.5 10.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Jnk-SapK_ap_N PF09744.4 AEO71114.1 - 0.022 14.7 18.4 0.02 14.8 11.4 1.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4296 PF14129.1 AEO71114.1 - 0.034 14.2 0.3 0.16 12.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) MbeD_MobD PF04899.7 AEO71114.1 - 0.074 12.9 4.2 1.9 8.4 0.3 2.7 1 1 1 2 2 2 0 MbeD/MobD like Tropomyosin_1 PF12718.2 AEO71114.1 - 0.077 12.8 15.6 0.32 10.8 10.4 2.0 1 1 0 1 1 1 0 Tropomyosin like Laminin_II PF06009.7 AEO71114.1 - 0.083 12.6 3.2 0.097 12.4 1.7 1.5 1 1 1 2 2 1 0 Laminin Domain II GAS PF13851.1 AEO71114.1 - 0.092 11.9 16.8 0.11 11.7 5.9 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding MAD PF05557.8 AEO71114.1 - 0.12 10.4 19.0 0.02 13.0 5.4 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein Apolipo_F PF15148.1 AEO71114.1 - 0.14 11.4 3.9 0.13 11.5 1.9 1.6 1 1 1 2 2 2 0 Apolipoprotein F AAA_13 PF13166.1 AEO71114.1 - 0.16 10.4 8.0 0.2 10.0 5.6 1.2 1 0 0 1 1 1 0 AAA domain AKNA PF12443.3 AEO71114.1 - 0.17 11.8 3.6 0.069 13.1 0.6 1.8 2 0 0 2 2 1 0 AT-hook-containing transcription factor Fib_alpha PF08702.5 AEO71114.1 - 0.19 11.8 4.1 0.17 11.9 1.4 2.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF904 PF06005.7 AEO71114.1 - 0.41 10.9 21.1 12 6.2 4.3 3.6 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF342 PF03961.8 AEO71114.1 - 0.47 8.8 6.5 0.4 9.0 3.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) CENP-F_leu_zip PF10473.4 AEO71114.1 - 0.56 10.0 14.2 0.62 9.9 2.4 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin-6_N PF09177.6 AEO71114.1 - 0.6 10.5 11.5 1.6 9.1 0.8 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal IncA PF04156.9 AEO71114.1 - 0.76 9.3 19.6 14 5.2 13.6 2.0 1 1 0 1 1 1 0 IncA protein Lge1 PF11488.3 AEO71114.1 - 0.92 9.7 13.1 0.61 10.3 3.1 2.6 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Uds1 PF15456.1 AEO71114.1 - 1.2 9.1 17.9 0.45 10.5 7.1 2.2 1 1 1 2 2 2 0 Up-regulated During Septation BRE1 PF08647.6 AEO71114.1 - 1.4 8.9 13.0 2.4 8.2 3.9 3.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase V_ATPase_I PF01496.14 AEO71114.1 - 1.5 6.5 8.1 1.9 6.2 5.4 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 AEO71114.1 - 2 8.0 13.6 2.6 7.6 8.9 1.6 1 1 1 2 2 2 0 Mnd1 family DivIC PF04977.10 AEO71114.1 - 2 7.9 21.0 2.5 7.6 0.4 4.2 1 1 4 5 5 5 0 Septum formation initiator Seadorna_VP6 PF07407.6 AEO71114.1 - 2.3 6.8 4.8 1.5 7.4 1.4 1.9 1 1 0 2 2 2 0 Seadornavirus VP6 protein DUF3373 PF11853.3 AEO71114.1 - 2.3 6.6 5.1 5.4 5.4 3.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) PV-1 PF06637.6 AEO71114.1 - 3.5 6.0 13.0 5 5.5 9.0 1.4 1 0 0 1 1 1 0 PV-1 protein (PLVAP) ADIP PF11559.3 AEO71114.1 - 3.8 7.4 19.3 1.7 8.4 7.2 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 AEO71114.1 - 3.8 7.2 14.0 2.9 7.6 5.8 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin PF00804.20 AEO71114.1 - 3.9 7.7 7.5 16 5.7 5.1 2.0 1 1 0 1 1 1 0 Syntaxin EMP24_GP25L PF01105.19 AEO71114.1 - 3.9 7.1 6.8 0.61 9.7 0.9 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4407 PF14362.1 AEO71114.1 - 4.8 6.0 8.2 7.1 5.4 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Kinetocho_Slk19 PF12709.2 AEO71114.1 - 6.7 6.8 13.9 5.6 7.1 0.8 3.5 1 1 2 3 3 3 0 Central kinetochore-associated FliT PF05400.8 AEO71114.1 - 6.8 7.1 13.9 0.27 11.6 3.6 2.4 2 1 0 2 2 2 0 Flagellar protein FliT Atg14 PF10186.4 AEO71114.1 - 8.3 5.2 16.0 23 3.7 11.1 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Shugoshin_N PF07558.6 AEO71114.1 - 8.4 6.2 13.2 12 5.6 3.4 3.6 3 2 1 4 4 3 0 Shugoshin N-terminal coiled-coil region Prefoldin_2 PF01920.15 AEO71114.1 - 8.7 6.1 11.4 3.9 7.2 1.2 2.9 1 1 2 3 3 3 0 Prefoldin subunit Macoilin PF09726.4 AEO71114.1 - 9 4.4 15.3 11 4.1 10.6 1.1 1 0 0 1 1 1 0 Transmembrane protein CENP-Q PF13094.1 AEO71114.1 - 9.1 6.2 18.2 35 4.3 12.0 2.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Reo_sigmaC PF04582.7 AEO71115.1 - 0.011 14.9 2.8 0.016 14.4 1.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein WXG100 PF06013.7 AEO71115.1 - 0.46 10.5 5.5 1.3 9.0 0.4 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG IF-2B PF01008.12 AEO71115.1 - 0.58 9.0 3.2 0.96 8.3 2.2 1.3 1 0 0 1 1 1 0 Initiation factor 2 subunit family LMBR1 PF04791.11 AEO71115.1 - 3.8 5.9 10.1 4.9 5.6 7.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein SOBP PF15279.1 AEO71115.1 - 5.4 7.2 16.8 7.6 6.8 11.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein HOOK PF05622.7 AEO71115.1 - 9.4 3.9 35.2 12 3.5 24.4 1.0 1 0 0 1 1 1 0 HOOK protein Smg4_UPF3 PF03467.10 AEO71116.1 - 1.5e-33 116.2 0.0 4.6e-33 114.6 0.0 1.8 1 1 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.17 AEO71116.1 - 7.8e-10 38.2 0.8 2e-07 30.5 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO71116.1 - 1.2e-08 34.7 0.0 8.9e-07 28.8 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO71116.1 - 8.6e-05 22.3 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.23 AEO71117.1 - 8.7e-37 126.4 0.0 9.5e-32 110.0 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase NOSIC PF08060.8 AEO71117.1 - 0.14 12.0 0.0 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 NOSIC (NUC001) domain Thr_synth_N PF14821.1 AEO71118.1 - 1e-27 95.9 0.0 2.1e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 AEO71118.1 - 1.7e-19 70.1 0.0 1.6e-18 66.9 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DSPc PF00782.15 AEO71119.1 - 2.8e-24 85.1 0.0 3.2e-20 72.0 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AEO71119.1 - 0.00031 20.1 0.1 0.0042 16.4 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 AEO71119.1 - 0.051 13.6 0.3 0.97 9.4 0.1 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate WD40 PF00400.27 AEO71120.1 - 2e-06 27.4 0.5 0.0019 18.0 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat CPSF_A PF03178.10 AEO71120.1 - 0.014 14.4 0.0 13 4.6 0.0 3.1 3 0 0 3 3 3 0 CPSF A subunit region Adaptin_N PF01602.15 AEO71121.1 - 9.6e-86 288.1 2.8 1.1e-85 287.9 2.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 AEO71121.1 - 1e-38 131.7 0.0 3.4e-38 130.0 0.0 1.9 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 AEO71121.1 - 9.9e-20 70.9 0.0 1.7e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Xpo1 PF08389.7 AEO71121.1 - 0.26 11.1 3.2 2.9 7.7 0.1 2.8 3 1 0 3 3 3 0 Exportin 1-like protein Methyltransf_11 PF08241.7 AEO71123.1 - 2.6e-09 37.4 0.0 7.1e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO71123.1 - 9.1e-09 35.2 0.0 1.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO71123.1 - 1.4e-06 28.7 0.0 2.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO71123.1 - 4.3e-05 23.1 0.0 0.00015 21.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO71123.1 - 0.0098 15.0 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 AEO71123.1 - 0.039 14.5 0.0 0.43 11.1 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 AEO71123.1 - 0.048 14.0 0.0 0.11 12.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain TAF4 PF05236.9 AEO71125.1 - 7e-06 25.5 6.2 0.0033 16.7 3.1 3.8 3 1 0 3 3 3 2 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.3 AEO71126.1 - 4.2e-78 261.6 0.0 6.7e-76 254.4 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 AEO71126.1 - 5e-32 110.5 0.0 1.3e-31 109.2 0.0 1.7 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 AEO71126.1 - 1.2e-14 54.4 0.7 3.3e-14 52.9 0.5 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AEO71126.1 - 8.7e-12 44.9 0.6 1.7e-11 44.0 0.4 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 AEO71126.1 - 2.5e-07 30.3 0.1 4.8e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 AEO71126.1 - 1.5e-05 24.7 0.2 4.1e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF2360 PF10152.4 AEO71126.1 - 0.011 16.0 3.3 0.032 14.5 2.3 1.7 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF3446 PF11928.3 AEO71126.1 - 3.1 8.0 13.8 11 6.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Uds1 PF15456.1 AEO71127.1 - 1e-44 151.4 8.3 1e-44 151.4 5.7 8.7 3 2 5 8 8 8 1 Up-regulated During Septation HR1 PF02185.11 AEO71127.1 - 0.0015 18.2 4.0 0.0015 18.2 2.8 10.2 5 2 4 10 10 10 2 Hr1 repeat HOOK PF05622.7 AEO71127.1 - 0.0025 15.7 9.2 0.0025 15.7 6.4 5.3 3 1 1 5 5 5 2 HOOK protein MtrG PF04210.8 AEO71127.1 - 0.54 9.9 1.4 34 4.2 0.0 3.8 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF1751 PF08551.5 AEO71128.1 - 3e-05 24.2 0.8 5.6e-05 23.4 0.6 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 AEO71128.1 - 0.0033 17.4 1.9 0.0033 17.4 1.3 2.2 2 1 0 2 2 2 1 Rhomboid family Prenyltransf PF01255.14 AEO71129.1 - 4e-89 297.5 0.0 7.2e-89 296.7 0.0 1.3 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase PHD PF00628.24 AEO71130.1 - 3.9e-10 39.2 8.1 6.7e-10 38.4 5.6 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 AEO71130.1 - 4.4e-06 26.9 2.7 9.6e-06 25.8 0.1 2.7 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding SSP160 PF06933.6 AEO71130.1 - 0.78 7.6 27.5 0.98 7.3 14.7 2.3 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 LRR_6 PF13516.1 AEO71131.1 - 0.024 14.6 0.0 2.4 8.5 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.2 AEO71131.1 - 0.041 13.5 0.6 1 9.0 0.0 3.3 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 AEO71131.1 - 0.05 13.3 0.1 0.18 11.5 0.0 2.1 1 0 0 1 1 1 0 F-box-like LRR_1 PF00560.28 AEO71131.1 - 0.12 12.4 0.1 36 4.9 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat BCL9 PF11502.3 AEO71131.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein LRR_8 PF13855.1 AEO71131.1 - 0.14 11.9 1.1 5.2 6.9 0.0 3.7 4 0 0 4 4 4 0 Leucine rich repeat V_ATPase_I PF01496.14 AEO71132.1 - 9.5e-300 995.9 0.0 1.1e-299 995.7 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TACC PF05010.9 AEO71132.1 - 0.013 15.2 0.0 0.2 11.4 0.0 2.1 1 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) CheZ PF04344.8 AEO71132.1 - 0.029 14.0 0.6 0.39 10.3 0.0 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ AAA_13 PF13166.1 AEO71132.1 - 0.036 12.5 1.0 0.23 9.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain Filament PF00038.16 AEO71132.1 - 0.052 13.0 3.5 1.3 8.4 0.1 2.3 2 0 0 2 2 2 0 Intermediate filament protein DUF1515 PF07439.6 AEO71132.1 - 0.61 9.9 0.0 0.61 9.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) APH PF01636.18 AEO71133.1 - 7.8e-15 55.2 0.4 1.7e-14 54.1 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 AEO71133.1 - 0.0012 17.5 0.0 0.0018 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 AEO71133.1 - 0.0049 16.0 0.0 0.0075 15.4 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 AEO71133.1 - 0.022 14.3 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 AEO71133.1 - 0.024 13.8 0.0 5.7 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.17 AEO71133.1 - 0.081 12.2 0.0 0.46 9.8 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Tcp11 PF05794.8 AEO71134.1 - 3.6e-80 269.8 0.0 4.5e-76 256.3 0.0 2.1 2 0 0 2 2 2 2 T-complex protein 11 DUF1242 PF06842.7 AEO71135.1 - 7.6e-20 70.1 2.5 1e-19 69.6 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF3317 PF11779.3 AEO71135.1 - 0.34 10.3 1.8 0.62 9.5 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) TFIID-18kDa PF02269.11 AEO71136.1 - 1.5e-19 69.6 0.0 2.4e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 AEO71136.1 - 0.00012 21.6 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.1 AEO71136.1 - 0.00017 21.7 0.0 0.00036 20.6 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AEO71136.1 - 0.0018 18.2 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AEO71136.1 - 0.0028 17.7 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 AEO71136.1 - 0.046 14.0 0.1 0.1 12.8 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Macro PF01661.16 AEO71137.1 - 2.5e-18 66.1 0.0 5.5e-18 64.9 0.0 1.6 1 1 0 1 1 1 1 Macro domain EamA PF00892.15 AEO71138.1 - 7.6e-17 61.5 18.7 7.4e-11 42.1 1.6 2.9 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 AEO71138.1 - 7.6e-05 22.8 3.8 7.6e-05 22.8 2.6 3.2 2 1 0 3 3 3 2 Multidrug resistance efflux transporter DUF606 PF04657.8 AEO71138.1 - 0.00062 19.8 1.3 0.00062 19.8 0.9 2.7 2 1 0 2 2 2 1 Protein of unknown function, DUF606 Gemini_AC4_5_2 PF08464.5 AEO71138.1 - 0.019 14.6 0.4 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Geminivirus AC4/5 conserved region UAA PF08449.6 AEO71138.1 - 0.04 12.8 2.6 0.092 11.6 0.1 2.0 2 0 0 2 2 2 0 UAA transporter family Antimicrobial10 PF08105.6 AEO71138.1 - 0.16 11.6 1.0 0.73 9.4 0.5 2.2 2 0 0 2 2 2 0 Metchnikowin family TIP49 PF06068.8 AEO71139.1 - 7.6e-187 620.8 0.1 8.8e-187 620.6 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 AEO71139.1 - 8e-11 42.2 0.9 5.9e-07 29.7 0.1 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AEO71139.1 - 1.5e-10 40.5 1.1 4.4e-07 29.1 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AEO71139.1 - 2.9e-05 23.7 0.1 6.9e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 AEO71139.1 - 0.00022 21.2 0.0 0.08 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AEO71139.1 - 0.00023 21.2 0.1 0.82 9.8 0.1 2.5 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 AEO71139.1 - 0.0013 18.2 0.1 0.006 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 AEO71139.1 - 0.0021 18.0 0.2 0.0053 16.7 0.1 1.7 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 AEO71139.1 - 0.0048 16.6 0.1 0.1 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 AEO71139.1 - 0.0056 15.8 0.3 0.013 14.5 0.2 1.6 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 AEO71139.1 - 0.008 15.3 0.1 0.31 10.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 AEO71139.1 - 0.0095 15.3 0.2 0.022 14.1 0.1 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF2075 PF09848.4 AEO71139.1 - 0.014 14.3 0.0 0.068 12.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 AEO71139.1 - 0.029 13.2 0.0 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Sigma54_activat PF00158.21 AEO71139.1 - 0.03 13.8 0.1 0.73 9.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 AEO71139.1 - 0.039 14.2 0.1 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AEO71139.1 - 0.063 14.1 0.1 0.13 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain MinE PF03776.9 AEO71139.1 - 0.11 12.0 0.1 0.29 10.6 0.1 1.7 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE KaiC PF06745.8 AEO71139.1 - 0.12 11.4 0.8 0.49 9.4 0.1 2.1 2 0 0 2 2 2 0 KaiC AAA_33 PF13671.1 AEO71139.1 - 0.17 11.7 0.2 1.8 8.4 0.1 2.6 2 2 0 2 2 2 0 AAA domain HMG_box PF00505.14 AEO71140.1 - 1.5e-17 63.6 0.1 2.1e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AEO71140.1 - 1.3e-05 25.5 0.1 2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain DUF605 PF04652.11 AEO71141.1 - 3.4 6.9 10.3 4.4 6.5 7.1 1.1 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 AEO71142.1 - 1.4e-23 83.3 0.0 1.8e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71142.1 - 1.2e-11 44.1 0.0 1.3e-10 40.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO71143.1 - 1.3e-08 34.8 0.0 2.5e-08 33.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Dynactin PF12455.3 AEO71144.1 - 1.4e-91 306.2 8.3 1.4e-91 306.2 5.8 3.6 3 0 0 3 3 3 2 Dynein associated protein CAP_GLY PF01302.20 AEO71144.1 - 5.5e-23 80.4 0.4 9.1e-23 79.7 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain SRP19 PF01922.12 AEO71145.1 - 5.7e-27 94.1 0.0 1e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Myosin_tail_1 PF01576.14 AEO71146.1 - 0.0038 15.0 1.0 0.0046 14.7 0.7 1.0 1 0 0 1 1 1 1 Myosin tail Tropomyosin PF00261.15 AEO71146.1 - 0.0053 15.8 0.8 0.0072 15.4 0.5 1.1 1 0 0 1 1 1 1 Tropomyosin Striatin PF08232.7 AEO71146.1 - 0.0058 16.9 0.0 0.0072 16.6 0.0 1.2 1 0 0 1 1 1 1 Striatin family DUF1192 PF06698.6 AEO71146.1 - 0.019 14.7 1.1 0.05 13.4 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Cep57_CLD_2 PF14197.1 AEO71146.1 - 0.02 14.8 1.5 0.031 14.2 1.1 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Reo_sigmaC PF04582.7 AEO71146.1 - 0.12 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF2360 PF10152.4 AEO71146.1 - 1.1 9.5 4.4 2.3 8.4 3.0 1.6 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Methyltransf_31 PF13847.1 AEO71147.1 - 3.8e-28 97.9 0.0 5.2e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO71147.1 - 2.3e-17 63.2 0.0 4.5e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO71147.1 - 2.2e-14 53.5 0.0 3.2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO71147.1 - 9.9e-14 51.5 0.0 1.6e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO71147.1 - 5.5e-13 48.5 0.0 8.7e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 AEO71147.1 - 1.8e-11 44.3 0.0 2.7e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO71147.1 - 4.6e-11 43.3 0.0 8.1e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO71147.1 - 7.1e-10 38.9 0.1 1.3e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AEO71147.1 - 3.6e-06 26.6 0.0 6.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 AEO71147.1 - 4.5e-05 22.7 0.0 7.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 AEO71147.1 - 0.0036 16.7 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 AEO71147.1 - 0.0039 16.3 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase CheR PF01739.13 AEO71147.1 - 0.04 13.1 0.0 0.094 11.9 0.0 1.5 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain UPF0020 PF01170.13 AEO71147.1 - 0.057 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 AEO71147.1 - 0.072 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PemK PF02452.12 AEO71148.1 - 0.024 14.8 0.0 0.052 13.7 0.0 1.5 1 1 0 1 1 1 0 PemK-like protein Band_7 PF01145.20 AEO71149.1 - 8.4e-25 87.7 3.3 1.3e-24 87.1 2.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family AAA PF00004.24 AEO71150.1 - 3.3e-53 179.4 0.0 4.2e-39 133.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO71150.1 - 2.3e-11 43.9 0.1 0.00034 20.7 0.0 4.1 2 2 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 AEO71150.1 - 3e-09 36.3 0.4 5e-08 32.4 0.1 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 AEO71150.1 - 2e-08 34.2 0.0 0.0013 18.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 AEO71150.1 - 2.2e-08 33.2 0.0 0.0018 17.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 AEO71150.1 - 3.2e-08 33.7 0.0 0.0055 16.7 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.1 AEO71150.1 - 7.8e-08 31.9 0.3 0.019 14.6 0.0 2.9 3 0 0 3 3 2 2 Part of AAA domain AAA_17 PF13207.1 AEO71150.1 - 1.1e-07 32.7 0.0 0.014 16.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.13 AEO71150.1 - 4.8e-07 29.6 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 AEO71150.1 - 1.1e-06 27.8 0.9 0.032 13.2 0.0 2.9 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 AEO71150.1 - 1.3e-06 28.3 0.0 0.017 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 AEO71150.1 - 3.3e-06 27.4 0.1 0.036 14.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 AEO71150.1 - 3.5e-06 26.7 0.0 0.0016 18.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 AEO71150.1 - 1.2e-05 24.8 1.4 0.49 9.7 0.0 3.8 2 2 0 4 4 4 2 AAA domain AAA_2 PF07724.9 AEO71150.1 - 1.2e-05 25.2 0.0 0.00011 22.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 AEO71150.1 - 1.3e-05 24.4 0.8 0.0046 16.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 AEO71150.1 - 5.9e-05 22.2 0.0 0.079 12.0 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 AEO71150.1 - 6.8e-05 22.3 0.1 0.15 11.4 0.0 2.7 3 0 0 3 3 3 2 IstB-like ATP binding protein RNA_helicase PF00910.17 AEO71150.1 - 0.00015 21.8 0.0 0.078 13.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase KaiC PF06745.8 AEO71150.1 - 0.0002 20.5 0.1 0.022 13.8 0.2 2.4 2 0 0 2 2 2 1 KaiC Arch_ATPase PF01637.13 AEO71150.1 - 0.00086 19.0 0.1 25 4.4 0.0 3.9 2 2 2 4 4 4 0 Archaeal ATPase AAA_24 PF13479.1 AEO71150.1 - 0.0011 18.5 0.2 0.066 12.7 0.2 2.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 AEO71150.1 - 0.0013 18.3 0.1 1.5 8.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 AEO71150.1 - 0.0016 18.7 0.9 0.052 13.8 0.1 2.8 3 0 0 3 3 2 1 ABC transporter NACHT PF05729.7 AEO71150.1 - 0.0018 17.9 0.7 1.4 8.5 0.0 3.0 4 0 0 4 4 3 1 NACHT domain AAA_3 PF07726.6 AEO71150.1 - 0.0027 17.3 0.0 0.42 10.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 AEO71150.1 - 0.0028 17.6 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 AEO71150.1 - 0.004 16.6 0.1 1.2 8.5 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain PhoH PF02562.11 AEO71150.1 - 0.0052 16.0 0.0 2.1 7.5 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein KTI12 PF08433.5 AEO71150.1 - 0.0054 15.9 0.0 2.1 7.4 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Parvo_NS1 PF01057.12 AEO71150.1 - 0.0062 15.4 0.0 1.1 8.0 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 AEO71150.1 - 0.011 14.5 0.0 1.3 7.7 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain UPF0079 PF02367.12 AEO71150.1 - 0.018 14.6 0.0 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 AEO71150.1 - 0.07 12.7 0.0 0.46 10.0 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.4 AEO71150.1 - 0.071 12.0 0.0 0.5 9.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 AEO71150.1 - 0.076 12.5 0.0 1.4 8.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain DAP3 PF10236.4 AEO71150.1 - 0.22 10.4 0.0 3.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Cir_N PF10197.4 AEO71151.1 - 0.00032 20.6 2.0 0.00032 20.6 1.4 4.8 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Nop14 PF04147.7 AEO71153.1 - 0.035 12.0 6.0 0.039 11.8 4.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 AEO71153.1 - 0.32 8.9 4.6 0.37 8.7 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 AEO71153.1 - 0.33 10.5 8.5 0.072 12.6 3.5 1.5 1 1 1 2 2 2 0 YL1 nuclear protein DUF605 PF04652.11 AEO71153.1 - 2.4 7.4 22.4 3.3 7.0 15.5 1.3 1 0 0 1 1 1 0 Vta1 like Ebola_NP PF05505.7 AEO71153.1 - 2.6 6.0 10.4 3.3 5.6 7.2 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein BUD22 PF09073.5 AEO71153.1 - 5.3 5.9 9.8 8.1 5.3 6.8 1.4 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.7 AEO71153.1 - 5.8 6.5 10.1 9.1 5.9 7.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein KxDL PF10241.4 AEO71154.1 - 8.2e-34 115.3 1.9 1.1e-33 114.9 1.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein Mating_C PF12737.2 AEO71154.1 - 0.48 9.2 7.9 0.42 9.4 0.8 2.2 2 1 0 2 2 2 0 C-terminal domain of homeodomain 1 CTP_transf_1 PF01148.15 AEO71156.1 - 6.4e-17 62.0 6.5 4.4e-14 52.7 1.6 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family Gly-zipper_Omp PF13488.1 AEO71157.1 - 0.003 17.1 4.6 0.0078 15.8 3.5 1.5 1 1 1 2 2 2 2 Glycine zipper Gly-zipper_OmpA PF13436.1 AEO71157.1 - 0.0033 17.0 0.5 0.0039 16.8 0.4 1.1 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 AEO71157.1 - 0.012 15.0 3.3 0.018 14.5 2.3 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Romo1 PF10247.4 AEO71157.1 - 0.3 11.3 6.1 0.56 10.4 4.2 1.6 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Rick_17kDa_Anti PF05433.10 AEO71157.1 - 0.3 10.7 5.2 0.44 10.2 3.6 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain Transgly_assoc PF04226.8 AEO71157.1 - 0.35 10.9 8.8 44 4.2 6.1 2.6 1 1 0 1 1 1 0 Transglycosylase associated protein DUF1275 PF06912.6 AEO71157.1 - 2 7.5 6.8 2.3 7.3 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Bacteriocin_IIc PF10439.4 AEO71157.1 - 3.4 7.8 12.7 8 6.6 8.8 1.6 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DEAD PF00270.24 AEO71158.1 - 1.5e-33 115.6 0.0 3.5e-33 114.4 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 AEO71158.1 - 7e-20 70.3 0.0 1.4e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 AEO71158.1 - 7.8e-20 70.5 0.1 2.6e-19 68.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO71158.1 - 0.0032 17.3 0.0 0.012 15.4 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RasGEF PF00617.14 AEO71159.1 - 7.7e-49 165.9 0.1 1.2e-48 165.4 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 AEO71159.1 - 6e-14 52.0 0.4 1.1e-13 51.1 0.3 1.4 1 0 0 1 1 1 1 RasGEF N-terminal motif LRR_4 PF12799.2 AEO71160.1 - 0.013 15.1 0.0 18 5.0 0.0 3.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Ribosomal_S2 PF00318.15 AEO71161.1 - 2.1e-44 151.2 0.0 7.3e-22 77.6 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 vATP-synt_AC39 PF01992.11 AEO71162.1 - 2.5e-119 398.3 0.0 2.8e-119 398.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit SMC_Nse1 PF07574.8 AEO71162.1 - 0.11 12.0 0.0 0.4 10.2 0.0 1.8 2 0 0 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex DHHA1 PF02272.14 AEO71162.1 - 0.4 10.4 6.0 0.2 11.4 2.0 2.1 2 0 0 2 2 2 0 DHHA1 domain Nop PF01798.13 AEO71163.1 - 3e-53 179.1 0.6 5.4e-53 178.3 0.4 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 AEO71163.1 - 2e-25 88.3 0.0 4.7e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 AEO71163.1 - 9.3e-20 70.5 1.0 9.3e-20 70.5 0.7 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF1777 PF08648.7 AEO71164.1 - 1.7e-05 24.6 59.0 1.7e-05 24.6 40.9 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) ubiquitin PF00240.18 AEO71164.1 - 0.00025 20.3 0.0 0.00039 19.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family MIP-T3 PF10243.4 AEO71164.1 - 0.0087 14.5 29.4 0.0098 14.4 20.3 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Mucin PF01456.12 AEO71164.1 - 0.029 14.1 4.5 0.04 13.6 3.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein YukD PF08817.5 AEO71164.1 - 0.062 13.8 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Menin PF05053.8 AEO71164.1 - 8.5 4.4 6.9 12 3.9 4.8 1.2 1 0 0 1 1 1 0 Menin DNA_binding_1 PF01035.15 AEO71166.1 - 2.7e-24 84.7 0.0 3.7e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF3963 PF13124.1 AEO71167.1 - 0.055 13.2 0.2 0.091 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) CBFD_NFYB_HMF PF00808.18 AEO71168.1 - 4.1e-05 23.5 0.1 5.4e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Prefoldin_2 PF01920.15 AEO71169.1 - 1.4e-25 89.0 4.6 2.1e-25 88.5 3.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit MtrG PF04210.8 AEO71169.1 - 0.053 13.2 2.4 0.16 11.7 0.1 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF1319 PF07028.6 AEO71169.1 - 0.16 12.1 4.7 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) DUF2019 PF09450.5 AEO71169.1 - 0.23 11.3 1.3 4.4 7.2 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2019) Rho_Binding PF08912.6 AEO71169.1 - 0.58 10.5 0.1 0.58 10.5 0.1 2.8 2 1 1 3 3 3 0 Rho Binding Seryl_tRNA_N PF02403.17 AEO71169.1 - 0.72 9.8 9.1 4.3 7.4 0.1 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 AEO71169.1 - 0.74 9.3 7.7 5.4 6.5 0.0 2.1 2 0 0 2 2 2 0 IncA protein bZIP_1 PF00170.16 AEO71169.1 - 0.79 9.7 7.1 0.82 9.6 0.2 2.4 2 0 0 2 2 2 0 bZIP transcription factor AAA_23 PF13476.1 AEO71169.1 - 0.79 10.0 6.0 1.1 9.5 4.2 1.2 1 0 0 1 1 1 0 AAA domain Lipoprotein_20 PF13942.1 AEO71169.1 - 0.8 9.2 7.8 7.4 6.0 0.1 2.1 2 0 0 2 2 2 0 YfhG lipoprotein CENP-H PF05837.7 AEO71169.1 - 2.5 8.3 7.1 26 5.0 2.7 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF342 PF03961.8 AEO71169.1 - 4.5 5.5 6.8 7.4 4.8 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF342) Ead_Ea22 PF13935.1 AEO71169.1 - 7.8 6.8 10.2 3.5 7.9 3.4 2.0 1 1 0 2 2 2 0 Ead/Ea22-like protein DASH_Dad1 PF08649.5 AEO71170.1 - 6.5e-25 86.5 1.0 8.1e-25 86.2 0.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Glutaredoxin2_C PF04399.8 AEO71170.1 - 0.0072 15.9 0.1 0.0085 15.6 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain ATP-synt PF00231.14 AEO71170.1 - 0.02 14.2 0.1 0.023 14.0 0.1 1.0 1 0 0 1 1 1 0 ATP synthase WVELL PF14043.1 AEO71170.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 WVELL protein PilJ PF13675.1 AEO71170.1 - 0.089 13.1 0.2 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Ras PF00071.17 AEO71171.1 - 5.8e-48 162.3 0.0 7.7e-48 161.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO71171.1 - 2.3e-11 44.2 0.0 3.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO71171.1 - 1.3e-05 24.5 0.0 3e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Skp1_POZ PF03931.10 AEO71172.1 - 2.8e-14 52.9 0.0 3.9e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 AEO71172.1 - 0.015 15.3 0.0 0.02 14.8 0.0 1.3 1 1 0 1 1 1 0 BTB/POZ domain DBR1 PF05011.8 AEO71173.1 - 1.6e-47 161.0 0.0 2.8e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 AEO71173.1 - 5.4e-11 42.2 0.6 9.3e-11 41.4 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_6 PF13405.1 AEO71176.1 - 6.8e-09 34.8 1.7 0.002 17.8 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 AEO71176.1 - 6.7e-08 32.5 1.9 1.1e-07 31.8 1.3 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 AEO71176.1 - 1.2e-05 24.1 3.0 6.6e-05 21.9 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 AEO71176.1 - 0.00016 20.8 0.6 0.0018 17.5 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 AEO71176.1 - 0.00027 20.4 2.6 0.00027 20.4 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair Met_10 PF02475.11 AEO71177.1 - 5.6e-07 29.3 0.0 8.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 AEO71177.1 - 0.013 15.5 2.3 0.051 13.6 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 AEO71177.1 - 0.043 14.4 0.0 0.092 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PAT1 PF09770.4 AEO71177.1 - 5.6 5.0 9.6 6.9 4.7 6.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.11 AEO71178.1 - 1.1e-36 126.2 46.8 4.8e-36 124.2 19.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2470 PF10615.4 AEO71179.1 - 1.5e-14 53.9 0.0 2.6e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Fungal_trans PF04082.13 AEO71180.1 - 9e-15 54.2 3.7 1.8e-14 53.2 2.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO71180.1 - 9.6e-08 31.8 7.4 2e-07 30.7 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phosphoesterase PF04185.9 AEO71181.1 - 1.3e-22 80.4 0.3 3.4e-22 79.1 0.2 1.6 1 1 0 1 1 1 1 Phosphoesterase family DUF1777 PF08648.7 AEO71182.1 - 1.4 8.6 9.3 1.6 8.4 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Perilipin PF03036.11 AEO71183.1 - 7.8e-05 21.6 0.1 0.00017 20.5 0.0 1.6 1 1 1 2 2 2 1 Perilipin family Pirin PF02678.11 AEO71184.1 - 1.1e-30 105.6 0.0 2.2e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 AEO71184.1 - 1.7e-23 82.6 0.0 1.1e-22 80.0 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 AEO71184.1 - 1.1e-06 27.9 3.6 6.7e-06 25.5 0.4 2.4 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 AEO71184.1 - 0.0091 15.3 0.7 0.78 9.1 0.0 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF861) zf-HIT PF04438.11 AEO71185.1 - 1.3e-09 37.5 8.7 2e-09 36.9 6.0 1.3 1 0 0 1 1 1 1 HIT zinc finger AF-4 PF05110.8 AEO71185.1 - 1.5 6.6 28.7 3 5.6 19.9 1.5 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Cwf_Cwc_15 PF04889.7 AEO71185.1 - 2.5 7.7 7.7 5.9 6.5 5.3 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.5 AEO71185.1 - 4.4 6.2 18.6 8.6 5.3 12.9 1.4 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 AEO71185.1 - 4.5 5.0 13.8 6.3 4.5 9.6 1.1 1 0 0 1 1 1 0 Nop14-like family HeLo PF14479.1 AEO71187.1 - 0.00091 19.0 0.1 0.0046 16.7 0.0 1.9 2 0 0 2 2 2 1 Prion-inhibition and propagation Pkinase PF00069.20 AEO71188.1 - 2.5e-22 79.2 0.0 3.1e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71188.1 - 1e-11 44.4 0.0 1.2e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO71188.1 - 0.058 13.1 0.2 2.1 8.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.2 AEO71189.1 - 1.2e-07 31.9 0.0 1.8e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 AEO71189.1 - 4.8e-07 29.8 0.2 0.0033 17.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 AEO71189.1 - 1.3e-06 27.8 0.4 0.049 13.4 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 AEO71189.1 - 1.3e-05 25.5 1.4 0.0057 17.1 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO71189.1 - 1.4e-05 24.9 0.1 0.099 12.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 AEO71190.1 - 3.4e-16 58.9 1.3 5.1e-09 36.0 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 AEO71190.1 - 1e-15 56.6 0.5 4.9e-05 22.9 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 AEO71190.1 - 1e-15 57.7 0.1 6.9e-09 35.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AEO71190.1 - 1.1e-14 54.4 0.3 3e-07 30.7 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO71190.1 - 5e-13 47.9 0.1 0.0013 18.7 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat DENN PF02141.16 AEO71191.1 - 5.3e-40 137.1 0.0 9.3e-40 136.3 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 AEO71191.1 - 1.1e-05 25.2 0.2 4.9e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 uDENN domain Dfp1_Him1_M PF08630.5 AEO71191.1 - 0.03 14.0 1.6 0.28 10.9 1.0 2.2 2 0 0 2 2 2 0 Dfp1/Him1, central region Elongin_A PF06881.6 AEO71191.1 - 2 8.7 12.2 0.052 13.9 3.4 2.1 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2570 PF10828.3 AEO71191.1 - 5.4 6.6 11.8 4.4 6.9 6.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) LSM14 PF12701.2 AEO71192.1 - 2.8e-34 116.8 0.0 5.6e-34 115.8 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 AEO71192.1 - 7.9e-19 68.1 0.8 7.9e-19 68.1 0.5 2.0 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 AEO71192.1 - 3.3e-06 26.9 0.0 6.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain LPP PF04728.8 AEO71192.1 - 3.3 7.5 6.8 6.2 6.7 2.7 2.3 1 1 1 2 2 2 0 Lipoprotein leucine-zipper CcmH PF03918.9 AEO71193.1 - 0.12 11.3 1.0 0.37 9.7 0.2 2.0 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Tcf25 PF04910.9 AEO71194.1 - 2.3e-76 257.0 0.2 3.5e-76 256.5 0.2 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 BLVR PF06375.6 AEO71194.1 - 0.064 13.0 12.9 0.025 14.4 6.7 2.0 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) RNase_H2-Ydr279 PF09468.5 AEO71194.1 - 1 8.5 5.2 2 7.5 3.6 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) HMA PF00403.21 AEO71195.1 - 5.4e-16 58.4 0.5 1.3e-15 57.2 0.1 1.7 1 1 1 2 2 2 2 Heavy-metal-associated domain DUF2583 PF10762.4 AEO71196.1 - 0.22 11.6 1.1 0.26 11.4 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) Aminotran_1_2 PF00155.16 AEO71197.1 - 3e-64 217.2 0.0 3.4e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 AEO71197.1 - 3.1e-05 23.1 0.0 6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 AEO71197.1 - 0.00015 21.0 0.0 0.00025 20.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 AEO71197.1 - 0.0018 16.6 0.0 0.0035 15.7 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 AEO71197.1 - 0.012 14.3 0.0 0.025 13.3 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-V Ras PF00071.17 AEO71198.1 - 1.6e-15 56.8 0.0 2.1e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO71198.1 - 7.5e-08 32.8 0.0 1.2e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 AEO71198.1 - 0.0015 17.8 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AEO71198.1 - 0.081 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase IIGP PF05049.8 AEO71198.1 - 0.13 11.0 0.2 0.32 9.7 0.1 1.5 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.1 AEO71198.1 - 0.28 10.7 0.3 0.47 9.9 0.2 1.3 1 0 0 1 1 1 0 AAA domain DUF2407_C PF13373.1 AEO71199.1 - 1.1e-28 99.9 0.0 2.4e-28 98.7 0.0 1.5 1 1 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 AEO71199.1 - 1.7e-23 82.6 0.0 3.1e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 AEO71199.1 - 0.041 13.2 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family SSP160 PF06933.6 AEO71199.1 - 2.1 6.2 4.4 2.7 5.8 3.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 rRNA_proc-arch PF13234.1 AEO71200.1 - 2.8e-90 302.1 0.0 7e-90 300.8 0.0 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 AEO71200.1 - 4.1e-56 189.0 4.0 7.3e-56 188.2 2.8 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 AEO71200.1 - 1.9e-21 76.2 0.0 9.6e-21 74.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO71200.1 - 2.6e-08 33.5 0.0 6.5e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prp19 PF08606.6 AEO71200.1 - 0.0012 18.5 1.6 0.067 12.9 0.3 2.6 2 0 0 2 2 2 1 Prp19/Pso4-like ResIII PF04851.10 AEO71200.1 - 0.0039 17.0 0.0 0.046 13.5 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 AEO71200.1 - 0.025 13.4 0.0 0.13 11.0 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein F-box-like PF12937.2 AEO71201.1 - 5.7e-06 25.9 0.1 2e-05 24.2 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO71201.1 - 0.002 17.7 1.8 0.0053 16.3 0.0 2.5 3 0 0 3 3 3 1 F-box domain Steroid_dh PF02544.11 AEO71202.1 - 2.7e-22 79.1 0.1 6.4e-22 77.9 0.0 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 AEO71202.1 - 0.00012 22.1 0.2 0.00047 20.2 0.2 2.1 1 1 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 AEO71202.1 - 0.00014 21.2 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Autoind_bind PF03472.10 AEO71202.1 - 0.048 12.9 0.0 0.095 11.9 0.0 1.4 1 0 0 1 1 1 0 Autoinducer binding domain SOG2 PF10428.4 AEO71204.1 - 1.1e-115 386.8 0.6 1.1e-115 386.8 0.4 2.2 2 0 0 2 2 2 1 RAM signalling pathway protein LRR_8 PF13855.1 AEO71204.1 - 5e-18 64.5 5.5 4.4e-08 32.7 0.0 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 AEO71204.1 - 3.3e-14 52.1 1.1 3.5e-05 23.3 0.0 3.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AEO71204.1 - 6.7e-08 31.5 3.2 0.46 10.6 0.0 5.1 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 AEO71204.1 - 9.4e-05 22.0 0.9 8.5 7.0 0.0 4.9 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 AEO71204.1 - 0.29 11.3 1.4 41 4.6 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat DEAD PF00270.24 AEO71206.1 - 5.9e-18 64.9 0.0 1.4e-17 63.7 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO71206.1 - 2.8e-17 62.3 0.0 1.3e-15 57.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AEO71206.1 - 0.15 10.7 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Ydc2-catalyt PF09159.5 AEO71207.1 - 3.1e-64 217.0 0.0 3.7e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.22 AEO71207.1 - 5.7e-08 32.0 0.8 1.3e-07 30.9 0.6 1.6 1 0 0 1 1 1 1 SAP domain Auts2 PF15336.1 AEO71207.1 - 0.02 14.9 2.2 0.034 14.1 1.5 1.3 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Pyr_redox_2 PF07992.9 AEO71208.1 - 1.8e-41 142.2 0.7 3e-41 141.5 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 AEO71208.1 - 7.3e-33 112.8 0.0 3e-32 110.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 AEO71208.1 - 2e-19 69.7 1.8 1.7e-17 63.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO71208.1 - 1.2e-09 38.5 0.1 2.3e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO71208.1 - 0.00043 19.4 0.2 0.00074 18.7 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AEO71208.1 - 0.0011 17.4 5.2 0.7 8.2 1.2 3.0 2 1 1 3 3 3 2 HI0933-like protein K_oxygenase PF13434.1 AEO71208.1 - 0.0012 17.8 0.1 0.013 14.4 0.0 2.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 AEO71208.1 - 0.0039 16.7 0.3 2.7 7.5 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 AEO71208.1 - 0.0077 15.1 7.1 0.84 8.4 0.1 2.9 3 0 0 3 3 3 2 FAD binding domain Thi4 PF01946.12 AEO71208.1 - 0.019 14.0 0.4 0.04 13.0 0.3 1.5 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 AEO71208.1 - 0.021 13.7 3.0 0.18 10.6 1.6 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 AEO71208.1 - 0.022 13.6 4.3 0.088 11.6 2.7 2.2 3 1 0 3 3 3 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 AEO71208.1 - 0.1 11.7 0.1 0.81 8.8 0.0 2.2 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 AEO71208.1 - 0.16 11.9 1.4 0.44 10.6 1.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 AEO71208.1 - 0.23 11.0 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain COX7C PF02935.11 AEO71209.1 - 1.7e-14 53.3 0.2 2.3e-14 52.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Deltaretro_Tax PF05599.6 AEO71209.1 - 0.052 13.8 1.3 0.052 13.8 0.9 1.5 2 0 0 2 2 2 0 Deltaretrovirus Tax protein APH PF01636.18 AEO71211.1 - 2e-17 63.7 0.8 5.2e-17 62.3 0.3 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO71211.1 - 0.00086 18.9 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 AEO71211.1 - 0.0087 15.0 0.0 0.047 12.6 0.0 1.9 2 0 0 2 2 2 1 Fructosamine kinase RIO1 PF01163.17 AEO71211.1 - 0.079 12.2 0.0 0.33 10.2 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Sec6 PF06046.8 AEO71213.1 - 5.9e-162 539.6 6.9 8.3e-162 539.1 4.8 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 AEO71213.1 - 0.00053 18.8 3.0 0.00053 18.8 2.1 1.9 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF2450 PF10475.4 AEO71213.1 - 0.0081 15.0 6.4 0.0084 15.0 1.1 2.4 1 1 1 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) NPV_P10 PF05531.7 AEO71213.1 - 0.081 13.1 2.6 39 4.5 0.9 3.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DASH_Duo1 PF08651.5 AEO71213.1 - 0.23 11.0 3.5 0.75 9.4 0.2 3.5 4 0 0 4 4 4 0 DASH complex subunit Duo1 Retrotrans_gag PF03732.12 AEO71213.1 - 0.96 9.5 4.7 2.9 8.0 0.0 4.3 5 1 0 5 5 5 0 Retrotransposon gag protein DASH_Dam1 PF08653.5 AEO71213.1 - 5.6 6.8 5.8 38 4.1 0.1 4.7 4 1 2 6 6 6 0 DASH complex subunit Dam1 Zn_Tnp_IS1 PF03811.8 AEO71214.1 - 1.1 8.8 7.6 4.8 6.7 1.0 2.5 2 0 0 2 2 2 0 InsA N-terminal domain Ima1_N PF09779.4 AEO71215.1 - 1.2e-44 151.9 2.3 1.9e-44 151.2 1.6 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.2 AEO71215.1 - 0.022 14.5 5.9 0.14 11.9 0.3 2.6 2 1 0 2 2 2 0 Double zinc ribbon RNHCP PF12647.2 AEO71215.1 - 0.048 13.4 0.3 0.048 13.4 0.2 2.4 3 0 0 3 3 3 0 RNHCP domain OrfB_Zn_ribbon PF07282.6 AEO71215.1 - 0.076 12.6 2.7 0.14 11.8 0.5 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF1469 PF07332.6 AEO71216.1 - 2.8 7.6 5.0 3.5 7.3 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Alg14 PF08660.6 AEO71217.1 - 7.6e-48 162.7 0.0 8.8e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like MRP-S25 PF13741.1 AEO71218.1 - 4.2e-71 239.0 5.8 2e-69 233.5 4.0 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 PPR_2 PF13041.1 AEO71219.1 - 4.6e-19 68.1 0.0 5.3e-08 32.7 0.0 4.7 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.1 AEO71219.1 - 5.6e-13 48.0 7.3 0.041 14.1 0.0 7.2 7 0 0 7 7 7 5 Pentatricopeptide repeat domain PPR PF01535.15 AEO71219.1 - 2.5e-12 45.8 9.4 3.4e-05 23.5 0.0 5.8 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.2 AEO71219.1 - 3.3e-10 39.2 3.1 0.0005 19.4 0.1 5.3 5 0 0 5 5 5 2 PPR repeat PMP22_Claudin PF00822.15 AEO71220.1 - 0.00062 19.4 0.2 0.00062 19.4 0.1 2.0 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family DUF2835 PF11197.3 AEO71220.1 - 0.15 11.8 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) COX4_pro PF03626.9 AEO71220.1 - 3.2 7.9 7.9 27 4.9 5.5 2.5 1 1 0 1 1 1 0 Prokaryotic Cytochrome C oxidase subunit IV Tetraspannin PF00335.15 AEO71220.1 - 5.6 6.1 7.4 7.5 5.7 5.1 1.3 1 1 0 1 1 1 0 Tetraspanin family Thiolase_C PF02803.13 AEO71221.1 - 1.3e-09 37.5 1.4 4e-09 35.9 0.2 2.4 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 AEO71221.1 - 1.4e-07 31.1 0.6 8.2e-06 25.3 0.0 2.9 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 AEO71221.1 - 2.8e-05 23.2 0.0 2.8e-05 23.2 0.0 2.1 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 AEO71221.1 - 0.0075 15.7 0.2 0.0075 15.7 0.2 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 AEO71221.1 - 0.039 12.4 0.2 0.066 11.6 0.1 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.17 AEO71221.1 - 0.054 13.3 0.1 2.6 7.9 0.0 2.7 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain DUF3208 PF11482.3 AEO71221.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) 2OG-FeII_Oxy PF03171.15 AEO71222.1 - 1.2e-05 25.5 0.0 2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 AEO71222.1 - 0.00042 20.7 0.0 0.00071 20.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aldedh PF00171.17 AEO71223.1 - 2.4e-140 467.9 0.0 2.8e-140 467.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 AEO71223.1 - 0.00015 20.6 0.2 0.13 11.0 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) RVT_1 PF00078.22 AEO71225.1 - 0.14 11.4 0.1 0.16 11.3 0.1 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_30 PF02055.11 AEO71227.1 - 9.3e-19 66.9 1.0 1.6e-11 43.1 0.4 2.5 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 AEO71227.1 - 8.3e-14 51.3 0.0 1.7e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF1966 PF09260.6 AEO71227.1 - 0.053 13.6 0.5 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1966) Ufd2P_core PF10408.4 AEO71228.1 - 4.2e-205 682.7 3.0 4.9e-205 682.4 2.1 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 AEO71228.1 - 2.1e-25 88.4 0.9 7.4e-25 86.7 0.6 2.0 1 0 0 1 1 1 1 U-box domain zf-TRAF PF02176.13 AEO71229.1 - 6.5e-13 48.8 31.6 6.1e-06 26.5 8.4 3.6 2 1 1 3 3 3 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 AEO71229.1 - 2.9e-08 33.5 8.0 2.9e-08 33.5 5.6 4.2 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO71229.1 - 1.6e-07 30.8 2.8 1.6e-07 30.8 1.9 3.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO71229.1 - 6.7e-07 28.8 8.3 6.7e-07 28.8 5.7 4.1 3 2 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO71229.1 - 7.6e-07 28.8 7.7 7.6e-07 28.8 5.3 3.6 3 1 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.1 AEO71229.1 - 3.9e-06 26.4 5.3 3.9e-06 26.4 3.7 3.3 2 1 1 3 3 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AEO71229.1 - 0.00015 21.5 8.9 0.00015 21.5 6.2 3.3 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 AEO71229.1 - 0.00095 18.8 4.4 0.00095 18.8 3.0 2.5 2 1 0 2 2 2 1 RING-type zinc-finger XhlA PF10779.4 AEO71229.1 - 0.01 15.7 0.5 0.023 14.5 0.4 1.6 1 0 0 1 1 1 0 Haemolysin XhlA PspA_IM30 PF04012.7 AEO71229.1 - 0.012 15.0 0.8 0.021 14.1 0.6 1.3 1 0 0 1 1 1 0 PspA/IM30 family DUF4598 PF15370.1 AEO71229.1 - 0.012 15.9 0.4 0.022 15.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) zf-RING_6 PF14835.1 AEO71229.1 - 0.022 14.5 2.3 0.022 14.5 1.6 2.2 2 1 1 3 3 3 0 zf-RING of BARD1-type protein zf-P11 PF03854.9 AEO71229.1 - 6.1 6.3 14.5 0.21 11.1 1.1 3.2 2 1 1 3 3 3 0 P-11 zinc finger zf-DNA_Pol PF08996.5 AEO71229.1 - 7.4 5.8 16.4 4.9 6.4 3.7 2.5 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger SPO22 PF08631.5 AEO71230.1 - 5.7e-80 268.3 0.2 1.2e-79 267.3 0.1 1.6 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 AEO71230.1 - 5.4e-07 29.4 3.8 0.0018 18.1 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Zn_clus PF00172.13 AEO71230.1 - 8.1e-05 22.4 7.7 0.00016 21.4 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.12 AEO71230.1 - 0.0099 15.7 3.3 0.14 12.1 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 AEO71230.1 - 0.043 14.2 0.3 20 5.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PAS PF00989.19 AEO71230.1 - 0.11 12.2 0.0 0.52 10.1 0.0 2.2 2 0 0 2 2 2 0 PAS fold TPR_1 PF00515.23 AEO71230.1 - 0.13 11.9 1.4 0.63 9.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ald_Xan_dh_C2 PF02738.13 AEO71231.1 - 2.7e-194 646.5 0.1 3.7e-194 646.0 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 AEO71231.1 - 4.2e-49 166.2 0.0 7.8e-49 165.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 AEO71231.1 - 1.5e-31 108.7 0.0 3.6e-31 107.4 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 AEO71231.1 - 3.8e-31 107.0 0.1 3.8e-31 107.0 0.1 2.7 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 AEO71231.1 - 5.8e-29 99.8 0.0 1.2e-28 98.8 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 AEO71231.1 - 3.3e-08 33.1 1.9 4.3e-08 32.7 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.12 AEO71231.1 - 0.021 14.3 0.1 0.056 12.9 0.1 1.7 2 0 0 2 2 2 0 DUF218 domain DUF3712 PF12505.3 AEO71232.1 - 3.2e-26 91.7 0.1 6.1e-26 90.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) DHC_N1 PF08385.7 AEO71233.1 - 0.017 13.5 0.0 5.6 5.2 0.0 3.5 3 1 0 4 4 4 0 Dynein heavy chain, N-terminal region 1 Serglycin PF04360.7 AEO71233.1 - 0.024 14.3 0.5 0.042 13.5 0.4 1.3 1 0 0 1 1 1 0 Serglycin Ret_tiss PF10044.4 AEO71233.1 - 0.057 13.9 0.1 28 5.3 0.0 4.0 2 1 2 4 4 4 0 Retinal tissue protein Adaptin_N PF01602.15 AEO71233.1 - 0.32 9.2 1.3 11 4.1 0.0 3.3 2 1 0 3 3 3 0 Adaptin N terminal region CRAL_TRIO PF00650.15 AEO71234.1 - 1.6e-39 134.9 0.0 2.5e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AEO71234.1 - 5.3e-12 45.6 0.5 2.3e-11 43.6 0.3 2.2 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AEO71234.1 - 5.2e-09 36.1 0.0 8.4e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pyr_redox_3 PF13738.1 AEO71235.1 - 1.3e-27 97.2 0.0 2.3e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_3 PF07859.8 AEO71235.1 - 1.9e-23 83.1 0.5 3.3e-23 82.3 0.3 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold FMO-like PF00743.14 AEO71235.1 - 2.8e-12 45.6 0.0 9.9e-12 43.8 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like DUF2424 PF10340.4 AEO71235.1 - 8.5e-10 37.8 0.0 1.5e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) NAD_binding_8 PF13450.1 AEO71235.1 - 2.7e-09 36.9 0.0 1.9e-07 31.0 0.0 3.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 AEO71235.1 - 1.1e-05 24.6 0.0 0.0003 19.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 AEO71235.1 - 1.4e-05 24.2 0.0 0.00025 20.0 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Abhydrolase_5 PF12695.2 AEO71235.1 - 5.9e-05 22.8 0.6 0.00015 21.5 0.4 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DAO PF01266.19 AEO71235.1 - 0.00065 18.7 1.1 0.016 14.1 0.0 3.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO71235.1 - 0.0011 19.2 0.1 0.21 12.0 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 AEO71235.1 - 0.026 12.7 0.0 0.067 11.3 0.0 1.6 1 1 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.9 AEO71235.1 - 0.026 14.4 0.1 0.7 9.7 0.1 2.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO71235.1 - 0.026 13.3 0.1 0.13 11.0 0.0 2.2 3 0 0 3 3 3 0 FAD binding domain Shikimate_DH PF01488.15 AEO71235.1 - 0.068 13.2 0.0 2.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 AEO71235.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase COesterase PF00135.23 AEO71235.1 - 0.2 10.3 0.0 2.5 6.7 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family adh_short PF00106.20 AEO71236.1 - 6.8e-29 100.9 8.2 2.6e-28 99.0 4.0 2.2 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO71236.1 - 1.4e-10 41.3 0.1 2.2e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO71236.1 - 4.7e-09 36.1 7.8 1.6e-08 34.3 5.4 1.9 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 AEO71236.1 - 8.1e-05 21.4 0.1 0.00012 20.9 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AEO71236.1 - 0.00071 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO71236.1 - 0.00087 19.3 1.2 0.0022 18.0 0.8 1.8 1 1 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 AEO71236.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.5 AEO71236.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Fungal_trans_2 PF11951.3 AEO71237.1 - 2.4e-08 32.9 0.0 1.3e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4290 PF14123.1 AEO71237.1 - 0.19 10.8 0.4 1.3 8.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4290) p450 PF00067.17 AEO71238.1 - 1.4e-74 251.2 0.0 1.9e-74 250.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF4551 PF15087.1 AEO71238.1 - 0.11 10.7 0.1 0.16 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) IBR PF01485.16 AEO71239.1 - 1.4e-11 44.1 55.0 5.2e-07 29.4 2.5 4.9 4 1 0 4 4 4 3 IBR domain Epimerase PF01370.16 AEO71241.1 - 1.6e-21 76.8 0.0 2.1e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO71241.1 - 5.1e-15 54.9 0.0 8.1e-15 54.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 AEO71241.1 - 2e-13 49.8 0.0 2.9e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 AEO71241.1 - 2.3e-11 44.0 3.4 6.5e-11 42.5 2.3 1.8 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 AEO71241.1 - 3e-09 37.0 1.5 7e-09 35.8 1.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 AEO71241.1 - 2.8e-07 29.7 0.1 3.9e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 AEO71241.1 - 2.1e-06 27.5 0.3 3.2e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 AEO71241.1 - 5.1e-05 22.6 0.1 0.00042 19.6 0.2 2.0 2 0 0 2 2 2 1 NmrA-like family F420_oxidored PF03807.12 AEO71241.1 - 0.00015 22.0 0.2 0.00063 20.1 0.0 2.1 3 0 0 3 3 2 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 AEO71241.1 - 0.027 13.3 0.1 0.064 12.1 0.1 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain Methyltransf_26 PF13659.1 AEO71241.1 - 0.51 10.3 4.4 2.5 8.1 3.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_M41 PF01434.13 AEO71242.1 - 6.1e-67 225.2 1.5 9.8e-67 224.5 1.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 AEO71242.1 - 1.2e-42 145.1 0.0 3.4e-42 143.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 AEO71242.1 - 1.9e-05 23.5 0.0 3.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 AEO71242.1 - 6.7e-05 22.9 1.6 0.0008 19.4 0.1 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 AEO71242.1 - 8.1e-05 23.4 0.0 0.00022 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO71242.1 - 9.4e-05 22.1 0.0 0.0003 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 AEO71242.1 - 0.00028 20.3 0.9 0.05 12.9 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 AEO71242.1 - 0.0007 19.4 0.0 0.0025 17.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AEO71242.1 - 0.00072 19.7 0.1 0.023 14.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AEO71242.1 - 0.00094 18.2 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AEO71242.1 - 0.0014 18.3 0.3 0.0051 16.5 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 AEO71242.1 - 0.0031 16.9 0.2 0.007 15.8 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 AEO71242.1 - 0.0079 15.3 1.4 0.026 13.6 0.4 2.2 1 1 1 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 AEO71242.1 - 0.019 14.1 0.2 0.045 12.9 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.13 AEO71242.1 - 0.021 14.4 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 AEO71242.1 - 0.022 13.8 0.0 1.4 7.9 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.1 AEO71242.1 - 0.036 14.0 0.0 0.084 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 AEO71242.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 AEO71242.1 - 0.053 12.4 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 AEO71242.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AEO71242.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Beta_protein PF14350.1 AEO71242.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Beta protein NACHT PF05729.7 AEO71242.1 - 0.19 11.4 0.2 1.2 8.7 0.1 2.1 2 0 0 2 2 2 0 NACHT domain Steroid_dh PF02544.11 AEO71243.1 - 1.3e-21 76.8 0.1 1.1e-20 73.9 0.1 2.1 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 AEO71243.1 - 0.011 15.0 0.3 0.017 14.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) DUF544 PF04424.8 AEO71244.1 - 1.3e-14 54.0 0.0 2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF3439 PF11921.3 AEO71244.1 - 0.12 12.1 4.2 0.24 11.1 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DnaJ PF00226.26 AEO71245.1 - 3.6e-24 84.2 0.3 6.6e-24 83.4 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 AEO71245.1 - 2.9e-23 82.1 0.0 6.5e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DUF2416 PF10315.4 AEO71246.1 - 0.0042 17.3 0.1 0.0049 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) Y_phosphatase2 PF03162.8 AEO71247.1 - 9.9e-45 151.8 0.0 1.4e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 AEO71247.1 - 1.8e-09 38.0 0.0 4.5e-09 36.7 0.0 1.6 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 AEO71247.1 - 0.003 17.1 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AEO71247.1 - 0.0036 16.6 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase adh_short PF00106.20 AEO71248.1 - 4.3e-31 108.0 3.8 5.8e-31 107.6 2.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO71248.1 - 5.8e-28 98.2 0.4 7e-28 98.0 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO71248.1 - 9.4e-13 48.2 3.9 2.6e-12 46.8 2.7 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO71248.1 - 5.7e-06 25.9 0.2 7.1e-06 25.6 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PepSY_TM_2 PF13703.1 AEO71249.1 - 0.036 14.2 0.5 0.074 13.2 0.3 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix HET PF06985.6 AEO71250.1 - 1.1e-19 70.9 0.0 2.9e-19 69.5 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_5 PF12695.2 AEO71251.1 - 3e-17 62.7 0.5 4.8e-17 62.0 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO71251.1 - 7.4e-06 26.0 11.5 0.00037 20.4 7.3 2.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 AEO71251.1 - 0.0019 17.1 0.0 0.0036 16.2 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.8 AEO71251.1 - 0.002 16.5 0.1 0.083 11.1 0.0 2.3 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.16 AEO71251.1 - 0.0098 15.1 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase PF07224.6 AEO71251.1 - 0.039 12.7 0.2 0.11 11.2 0.1 1.6 1 1 0 1 1 1 0 Chlorophyllase PGAP1 PF07819.8 AEO71251.1 - 0.055 13.0 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 AEO71251.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Pkinase PF00069.20 AEO71252.1 - 9.4e-18 64.2 0.0 1.3e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71252.1 - 6.4e-09 35.2 0.0 8e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO71252.1 - 5.4e-07 28.8 0.0 7.3e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AEO71252.1 - 8.1e-05 21.7 0.0 0.00036 19.6 0.0 1.8 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AEO71252.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 AEO71252.1 - 0.025 14.3 0.4 0.052 13.2 0.2 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AEO71252.1 - 0.039 12.8 0.1 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Glyco_hydro_30 PF02055.11 AEO71253.1 - 6.2e-16 57.6 0.2 1.8e-15 56.1 0.1 1.6 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Alpha-L-AF_C PF06964.7 AEO71253.1 - 0.00017 21.3 0.0 0.00026 20.8 0.0 1.4 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Glyco_hydr_30_2 PF14587.1 AEO71253.1 - 0.0079 15.1 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Allantoicase PF03561.10 AEO71253.1 - 0.073 12.5 1.3 0.17 11.3 0.5 1.8 2 0 0 2 2 2 0 Allantoicase repeat RabGAP-TBC PF00566.13 AEO71254.1 - 4.3e-48 163.6 0.0 6.6e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HET PF06985.6 AEO71255.1 - 2.1e-27 95.9 0.0 2.5e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3463 PF11946.3 AEO71256.1 - 0.096 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) Rep-A_N PF04057.7 AEO71257.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain Zip PF02535.17 AEO71257.1 - 0.35 9.8 1.7 0.53 9.2 1.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Septin PF00735.13 AEO71258.1 - 7.2e-113 376.2 0.8 8.6e-113 376.0 0.5 1.0 1 0 0 1 1 1 1 Septin AIG1 PF04548.11 AEO71258.1 - 7.9e-07 28.4 0.0 1.5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 AEO71258.1 - 2.1e-06 27.6 0.0 3.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 AEO71258.1 - 2.6e-05 23.4 0.0 4.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 AEO71258.1 - 0.00012 21.5 0.3 0.0039 16.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 AEO71258.1 - 0.00066 19.5 0.4 0.86 9.4 0.1 2.5 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 AEO71258.1 - 0.0025 17.3 0.0 0.0025 17.3 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 AEO71258.1 - 0.0043 17.4 0.0 0.0064 16.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AEO71258.1 - 0.0058 16.7 0.0 0.013 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 AEO71258.1 - 0.014 15.6 0.7 0.021 15.0 0.3 1.6 1 1 0 1 1 1 0 ABC transporter T2SE PF00437.15 AEO71258.1 - 0.015 14.2 0.1 0.039 12.8 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Gtr1_RagA PF04670.7 AEO71258.1 - 0.018 14.1 0.1 0.069 12.2 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region NB-ARC PF00931.17 AEO71258.1 - 0.029 13.2 0.0 0.052 12.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 AEO71258.1 - 0.038 13.9 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 AEO71258.1 - 0.049 13.0 0.1 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ras PF00071.17 AEO71258.1 - 0.066 12.6 0.1 0.22 10.8 0.0 1.9 2 1 0 2 2 2 0 Ras family Ribosomal_L32p PF01783.18 AEO71259.1 - 2.3e-13 50.0 6.1 3.4e-13 49.5 4.3 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family PolC_DP2 PF03833.8 AEO71259.1 - 0.0049 14.6 0.8 0.0055 14.4 0.5 1.0 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.7 AEO71259.1 - 0.024 14.4 3.0 0.037 13.8 2.1 1.2 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.2 AEO71259.1 - 0.17 11.7 4.3 0.48 10.2 3.0 1.7 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 AEO71259.1 - 0.58 9.4 6.0 7 6.0 1.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 AEO71259.1 - 2.8 7.9 6.3 5.8 6.9 1.2 2.2 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 AEO71259.1 - 2.8 7.5 6.4 9.6 5.8 0.3 2.4 2 1 0 2 2 2 0 zinc-ribbon domain WD40 PF00400.27 AEO71260.1 - 5e-22 76.9 12.3 1.8e-08 33.9 0.1 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_2 PF13360.1 AEO71260.1 - 0.00021 20.8 1.5 0.0037 16.7 0.5 2.2 1 1 1 2 2 2 1 PQQ-like domain Hira PF07569.6 AEO71260.1 - 0.00053 19.2 0.1 0.016 14.4 0.0 2.3 2 0 0 2 2 2 1 TUP1-like enhancer of split PQQ_3 PF13570.1 AEO71260.1 - 0.00099 19.3 1.6 0.54 10.6 0.1 3.1 2 0 0 2 2 2 2 PQQ-like domain eIF2A PF08662.6 AEO71260.1 - 0.0039 16.9 0.0 0.24 11.0 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 AEO71260.1 - 0.0081 14.9 0.0 0.053 12.2 0.0 2.1 2 0 0 2 2 2 1 Nup133 N terminal like Nup160 PF11715.3 AEO71260.1 - 0.019 13.1 0.7 0.11 10.6 0.2 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 AEO71260.1 - 0.02 13.2 0.1 0.046 12.0 0.1 1.6 1 1 0 1 1 1 0 Cytochrome D1 heme domain Nbas_N PF15492.1 AEO71260.1 - 0.049 12.7 0.0 5.8 5.9 0.0 3.2 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal DNA_pol_delta_4 PF04081.8 AEO71261.1 - 1.2e-28 99.8 0.0 1.7e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF2376 PF09550.5 AEO71261.1 - 0.042 13.9 0.0 0.099 12.8 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical phage protein (DUF2376) DUF2419 PF10343.4 AEO71262.1 - 6.3e-133 442.4 0.0 7.7e-133 442.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) DUF1563 PF07599.6 AEO71262.1 - 0.076 12.9 0.3 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1563) Prothymosin PF03247.9 AEO71263.1 - 0.043 13.9 11.8 0.072 13.2 8.2 1.4 1 1 0 1 1 1 0 Prothymosin/parathymosin family ThiF PF00899.16 AEO71264.1 - 1.2e-41 141.7 0.1 2.3e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 AEO71264.1 - 2e-30 104.1 0.3 4.7e-30 102.9 0.2 1.7 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 AEO71264.1 - 6.9e-25 86.9 0.4 1.8e-24 85.6 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 AEO71264.1 - 1.5e-18 65.9 0.8 1.5e-18 65.9 0.6 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 AEO71264.1 - 0.00018 21.6 0.0 0.00046 20.4 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 AEO71264.1 - 0.0015 18.5 0.0 0.0042 17.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 AEO71264.1 - 0.098 13.0 0.1 0.98 9.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 AEO71265.1 - 1.4e-24 86.8 3.5 4.2e-24 85.3 2.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO71265.1 - 6.7e-09 35.8 0.0 8.7e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO71265.1 - 4.2e-08 33.0 4.4 2.8e-07 30.3 3.0 2.2 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO71265.1 - 2.2e-07 31.0 1.1 2.4e-05 24.4 0.4 2.1 1 1 1 2 2 2 2 NADH(P)-binding Epimerase PF01370.16 AEO71265.1 - 2.3e-05 23.9 0.0 3.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 AEO71265.1 - 5.6e-05 22.2 0.0 7.1e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3HCDH_N PF02737.13 AEO71265.1 - 0.00054 19.6 0.0 0.00075 19.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AEO71265.1 - 0.00073 19.9 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 AEO71265.1 - 0.0025 16.7 0.0 0.003 16.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 AEO71265.1 - 0.0038 17.3 0.0 0.011 15.8 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 AEO71265.1 - 0.0039 16.1 0.0 0.0097 14.8 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain ApbA PF02558.11 AEO71265.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_3 PF03447.11 AEO71265.1 - 0.025 14.9 0.3 0.13 12.6 0.0 2.2 2 1 0 2 2 1 0 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 AEO71265.1 - 0.047 12.8 0.0 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DFP PF04127.10 AEO71265.1 - 0.079 12.5 0.2 0.13 11.8 0.1 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PAP2 PF01569.16 AEO71266.1 - 1.4e-18 66.7 2.6 4.1e-18 65.2 1.8 1.8 1 0 0 1 1 1 1 PAP2 superfamily JmjC PF02373.17 AEO71267.1 - 4.2e-37 126.8 0.6 1.6e-36 125.0 0.5 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 AEO71267.1 - 2.1e-21 75.9 3.3 3.6e-21 75.2 2.3 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 AEO71267.1 - 5.5e-21 74.5 4.0 1.2e-20 73.4 2.7 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 AEO71267.1 - 3.7e-14 51.9 1.7 8e-14 50.8 1.2 1.6 1 0 0 1 1 1 1 jmjN domain CENP-B_dimeris PF09026.5 AEO71267.1 - 2.1 8.6 8.5 6.1 7.1 5.9 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase PF00069.20 AEO71269.1 - 5.4e-09 35.5 0.0 7.3e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71269.1 - 9.1e-08 31.4 0.0 1.7e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.22 AEO71270.1 - 5.8e-06 25.8 0.1 6.8e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Metallophos_2 PF12850.2 AEO71271.1 - 3e-07 30.3 0.0 6.7e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AEO71271.1 - 1.3e-05 24.6 0.7 0.00035 20.0 0.5 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4440 PF14534.1 AEO71272.1 - 1.9e-05 24.8 0.0 2.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) AA_permease PF00324.16 AEO71273.1 - 3.4e-137 457.6 42.8 4.3e-137 457.3 29.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO71273.1 - 2.1e-33 115.5 46.3 2.8e-33 115.0 32.1 1.1 1 0 0 1 1 1 1 Amino acid permease zf-RING_2 PF13639.1 AEO71276.1 - 6.1e-15 54.7 4.4 6.1e-15 54.7 3.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 AEO71276.1 - 1e-09 37.8 12.6 3.4e-08 33.0 2.2 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO71276.1 - 1.5e-08 34.4 16.4 5.1e-08 32.8 3.5 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO71276.1 - 3.3e-08 33.5 0.7 3.3e-08 33.5 0.5 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 AEO71276.1 - 4.5e-08 32.6 12.2 1.8e-07 30.7 1.9 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.20 AEO71276.1 - 1.8e-06 27.5 13.9 1.8e-05 24.3 2.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 AEO71276.1 - 0.00054 19.4 2.9 0.0017 17.8 2.0 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 AEO71276.1 - 0.0011 18.7 1.9 0.0011 18.7 1.4 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.14 AEO71276.1 - 0.0056 16.3 1.4 0.0056 16.3 1.0 2.1 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family Cytochrom_CIII PF02085.11 AEO71276.1 - 0.016 15.3 3.1 0.016 15.3 2.1 2.0 2 0 0 2 2 2 0 Class III cytochrome C family DZR PF12773.2 AEO71276.1 - 0.024 14.4 1.8 0.024 14.4 1.3 2.6 2 1 0 2 2 2 0 Double zinc ribbon DUF1178 PF06676.6 AEO71276.1 - 0.17 12.0 3.0 0.27 11.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) zf-RING_UBOX PF13445.1 AEO71276.1 - 0.2 11.3 0.2 0.2 11.3 0.1 3.0 2 1 1 3 3 3 0 RING-type zinc-finger zf-RING_4 PF14570.1 AEO71276.1 - 0.29 10.7 13.2 0.81 9.3 1.9 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Pox_F17 PF04767.7 AEO71276.1 - 0.3 11.3 2.6 0.32 11.2 0.1 2.3 2 0 0 2 2 2 0 DNA-binding 11 kDa phosphoprotein Prok-RING_1 PF14446.1 AEO71276.1 - 0.39 10.4 12.3 3.1 7.6 0.3 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zinc-ribbons_6 PF07191.7 AEO71276.1 - 1.2 9.0 7.9 2.8 7.8 1.7 2.6 3 0 0 3 3 2 0 zinc-ribbons zf-TFIIB PF13453.1 AEO71276.1 - 1.7 7.8 5.2 6 6.1 0.2 3.2 3 0 0 3 3 3 0 Transcription factor zinc-finger zf-C3HC4_4 PF15227.1 AEO71276.1 - 8.3 6.3 14.0 8.7 6.3 1.5 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Dynamin_N PF00350.18 AEO71277.1 - 4.9e-15 55.7 0.0 1.2e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 AEO71277.1 - 2.9e-06 27.2 0.0 0.0043 17.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran PF00005.22 AEO71277.1 - 4.8e-05 23.6 0.0 0.0003 21.1 0.0 2.4 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 AEO71277.1 - 0.00019 20.6 0.0 0.0025 17.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 AEO71277.1 - 0.0019 18.1 9.6 0.0045 17.0 0.0 4.4 4 1 1 5 5 5 1 AAA ATPase domain AAA_29 PF13555.1 AEO71277.1 - 0.028 13.9 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 AEO71277.1 - 0.063 13.7 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 AEO71277.1 - 0.076 12.4 0.0 8.8 5.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 AEO71277.1 - 0.21 11.0 6.5 1.8 7.9 0.1 3.6 3 1 0 4 4 4 0 AAA-like domain AAA_21 PF13304.1 AEO71277.1 - 0.37 10.6 0.0 0.7 9.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain APH PF01636.18 AEO71278.1 - 2.9e-07 30.4 6.2 3e-07 30.4 1.5 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family MFS_1 PF07690.11 AEO71279.1 - 1.2e-39 136.0 79.7 6.3e-28 97.4 31.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 AEO71279.1 - 3e-05 23.7 3.8 0.0073 16.0 2.0 3.4 3 0 0 3 3 3 2 MFS_1 like family Spore_YtfJ PF09579.5 AEO71279.1 - 5.6 6.8 5.9 68 3.4 1.1 3.2 2 1 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) Fungal_trans PF04082.13 AEO71280.1 - 1.3e-17 63.5 0.1 2.7e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO71280.1 - 1e-08 34.9 11.2 1.9e-08 34.0 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 AEO71280.1 - 3.3 7.9 11.2 6 7.1 7.8 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Peptidase_M49 PF03571.10 AEO71281.1 - 2.4e-174 580.4 0.0 2.8e-174 580.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Fn_bind PF02986.9 AEO71282.1 - 0.092 12.2 0.3 0.24 10.9 0.2 1.7 1 0 0 1 1 1 0 Fibronectin binding repeat DNase_NucA_NucB PF14040.1 AEO71283.1 - 2.2e-26 92.2 0.3 3e-26 91.8 0.2 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB NB-ARC PF00931.17 AEO71285.1 - 1.2e-23 83.3 0.0 1.9e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 AEO71285.1 - 1.2e-22 79.5 17.1 2e-08 34.0 0.1 5.6 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 AEO71285.1 - 6.8e-11 41.7 22.0 0.003 17.4 1.1 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat AAA_22 PF13401.1 AEO71285.1 - 6.6e-06 26.2 0.0 2.9e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain TPR_11 PF13414.1 AEO71285.1 - 9.3e-06 25.2 13.3 0.0003 20.3 3.3 4.5 3 1 2 5 5 5 2 TPR repeat TPR_4 PF07721.9 AEO71285.1 - 2.7e-05 24.1 5.5 0.066 13.6 0.1 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 AEO71285.1 - 0.00012 21.4 11.6 0.022 14.3 0.5 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 AEO71285.1 - 0.00024 20.6 6.2 1.5 8.8 0.0 4.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 AEO71285.1 - 0.0071 16.4 1.9 2.8 8.3 0.0 3.7 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 AEO71285.1 - 0.018 15.4 18.3 0.78 10.1 0.1 5.4 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 AEO71285.1 - 0.03 14.0 7.7 16 5.5 0.3 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat IstB_IS21 PF01695.12 AEO71285.1 - 0.034 13.5 0.0 0.1 12.0 0.0 1.8 1 1 0 1 1 1 0 IstB-like ATP binding protein TPR_2 PF07719.12 AEO71285.1 - 0.045 13.6 18.7 7.1 6.8 0.7 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO71285.1 - 0.065 13.8 18.5 0.51 11.1 0.0 6.7 5 1 2 7 7 6 0 Tetratricopeptide repeat ArsA_ATPase PF02374.10 AEO71285.1 - 0.075 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase KaiC PF06745.8 AEO71285.1 - 0.08 12.0 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 KaiC APH PF01636.18 AEO71286.1 - 2.5e-21 76.4 1.3 2.5e-21 76.4 0.9 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 AEO71286.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase p450 PF00067.17 AEO71289.1 - 0.00037 19.1 1.5 0.0012 17.4 1.1 1.9 1 1 0 1 1 1 1 Cytochrome P450 IBR PF01485.16 AEO71290.1 - 4.1e-10 39.3 26.2 4.6e-07 29.6 2.2 3.8 2 1 1 3 3 3 2 IBR domain RRM_6 PF14259.1 AEO71290.1 - 2.3e-05 24.2 0.0 0.00095 19.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) C1_4 PF07975.7 AEO71290.1 - 8.6 6.4 16.3 19 5.3 0.2 3.8 3 0 0 3 3 3 0 TFIIH C1-like domain DUF3716 PF12511.3 AEO71291.1 - 2.5e-16 59.0 2.4 3.8e-16 58.4 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) SNARE PF05739.14 AEO71292.1 - 4.8e-10 38.9 0.9 1.2e-09 37.6 0.6 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 AEO71292.1 - 0.012 15.7 0.9 0.11 12.6 0.1 2.3 2 0 0 2 2 2 0 Syntaxin CorA PF01544.13 AEO71292.1 - 0.076 12.0 0.1 0.076 12.0 0.1 2.3 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein WD40 PF00400.27 AEO71293.1 - 1.4e-05 24.7 4.1 0.091 12.6 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat PPTA PF01239.17 AEO71295.1 - 1.8e-32 109.2 10.1 5.3e-08 31.8 0.2 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Med3 PF11593.3 AEO71295.1 - 0.019 14.2 6.4 0.024 13.8 4.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sporozoite_P67 PF05642.6 AEO71295.1 - 3.7 5.2 6.1 4.6 4.9 4.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ATP_bind_3 PF01171.15 AEO71296.1 - 5.4e-40 136.8 0.0 4e-29 101.4 0.0 2.2 2 0 0 2 2 2 2 PP-loop family Asn_synthase PF00733.16 AEO71296.1 - 0.00025 20.6 0.0 0.0008 18.9 0.0 1.8 2 0 0 2 2 2 1 Asparagine synthase tRNA_Me_trans PF03054.11 AEO71296.1 - 0.39 9.2 0.1 1.9 6.9 0.0 1.8 2 0 0 2 2 2 0 tRNA methyl transferase Mito_carr PF00153.22 AEO71297.1 - 1.2e-48 162.6 6.1 1.7e-18 66.1 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3337 PF11816.3 AEO71298.1 - 1.2e-80 271.3 0.0 9.1e-77 258.6 1.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 AEO71298.1 - 1.5e-26 91.2 6.7 1.7e-07 30.8 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 AEO71298.1 - 0.012 13.7 0.5 0.031 12.4 0.1 1.7 1 1 1 2 2 2 0 Nucleoporin Nup120/160 SnoaL_4 PF13577.1 AEO71300.1 - 9.9e-14 51.3 0.0 1.2e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Mito_carr PF00153.22 AEO71302.1 - 1.8e-64 213.5 2.0 9.9e-26 89.2 0.1 4.4 4 1 0 4 4 4 4 Mitochondrial carrier protein EF-hand_1 PF00036.27 AEO71302.1 - 5.9e-20 68.9 6.5 1.6e-05 23.8 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 AEO71302.1 - 2e-19 69.5 3.4 4.2e-13 49.2 1.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 AEO71302.1 - 6.8e-17 59.9 10.3 2.8e-05 23.2 0.2 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 AEO71302.1 - 7.1e-16 56.6 4.2 1.3e-05 24.6 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 AEO71302.1 - 1.8e-13 49.8 5.0 0.00012 21.5 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 AEO71302.1 - 8.6e-05 22.5 0.0 0.0016 18.4 0.0 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 AEO71302.1 - 0.014 15.0 1.1 1.4 8.5 0.0 2.7 2 1 1 3 3 3 0 EF hand EF-hand_4 PF12763.2 AEO71302.1 - 0.038 13.7 0.4 9.7 5.9 0.0 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Cyclin_N PF00134.18 AEO71303.1 - 1.8e-11 43.6 0.2 4.9e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF3498 PF12004.3 AEO71303.1 - 0.022 13.8 5.5 0.032 13.3 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Herpes_LMP2 PF07415.6 AEO71303.1 - 0.15 10.5 3.2 0.23 9.9 2.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein BTB PF00651.26 AEO71305.1 - 5.9e-05 23.0 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF4452 PF14618.1 AEO71306.1 - 5.5e-76 253.9 15.1 7.4e-76 253.5 10.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) LAP1C PF05609.7 AEO71306.1 - 0.07 11.7 3.3 0.078 11.6 2.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF1490 PF07371.7 AEO71308.1 - 0.028 14.3 0.1 0.083 12.8 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1490) DUF4228 PF14009.1 AEO71308.1 - 0.098 12.7 1.3 0.12 12.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) JmjC PF02373.17 AEO71309.1 - 9.5e-10 38.7 0.1 2.6e-09 37.3 0.1 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 AEO71309.1 - 6.7e-06 26.1 8.3 6.7e-06 26.1 5.7 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 AEO71309.1 - 0.017 14.6 0.0 0.045 13.2 0.0 1.6 1 0 0 1 1 1 0 Cupin domain HNH_5 PF14279.1 AEO71309.1 - 0.11 12.4 5.4 0.13 12.2 2.6 2.0 2 0 0 2 2 2 0 HNH endonuclease UbiA PF01040.13 AEO71310.1 - 3.7e-35 121.3 25.3 5e-35 120.9 17.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosom_S12_S23 PF00164.20 AEO71311.1 - 8e-41 138.2 0.6 9.4e-41 138.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ADK PF00406.17 AEO71313.1 - 3.2e-60 202.3 0.0 4e-60 202.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 AEO71313.1 - 5.3e-15 54.7 0.0 1.7e-14 53.1 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 AEO71313.1 - 3.5e-07 31.0 0.1 8.6e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AEO71313.1 - 5.7e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO71313.1 - 0.0013 19.0 0.0 0.0033 17.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 AEO71313.1 - 0.0047 16.0 0.0 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin HOOK PF05622.7 AEO71314.1 - 2.1e-12 45.7 53.9 2.1e-12 45.7 37.4 2.3 1 1 1 2 2 2 2 HOOK protein CH PF00307.26 AEO71314.1 - 0.00018 21.5 0.0 0.00083 19.3 0.0 2.3 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF904 PF06005.7 AEO71314.1 - 0.003 17.8 5.5 0.003 17.8 3.8 9.4 5 2 1 6 6 6 2 Protein of unknown function (DUF904) CENP-F_leu_zip PF10473.4 AEO71314.1 - 0.56 10.0 97.8 0.039 13.8 6.8 5.9 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 AEO71314.1 - 5.1 6.1 26.9 0.025 13.7 2.0 4.2 1 1 3 5 5 5 0 Reovirus sigma C capsid protein Inhibitor_I9 PF05922.11 AEO71315.1 - 0.0024 18.3 0.1 0.0037 17.7 0.1 1.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 MitMem_reg PF13012.1 AEO71316.1 - 2.6e-39 133.8 0.2 5.8e-39 132.7 0.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 AEO71316.1 - 9.9e-29 99.4 0.0 2e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GRP PF07172.6 AEO71317.1 - 0.0068 16.8 9.5 0.012 16.0 6.6 1.4 1 0 0 1 1 1 1 Glycine rich protein family MRAP PF15183.1 AEO71317.1 - 0.063 12.8 0.1 0.099 12.2 0.1 1.3 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family ODV-E18 PF10717.4 AEO71317.1 - 0.11 11.9 0.7 0.19 11.2 0.5 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Defensin_propep PF00879.13 AEO71317.1 - 0.14 12.1 5.1 0.16 11.9 1.9 2.0 1 1 1 2 2 2 0 Defensin propeptide Coprogen_oxidas PF01218.13 AEO71318.1 - 8.7e-134 444.6 0.0 1e-133 444.4 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.11 AEO71319.1 - 7.8e-51 170.3 0.2 9.2e-51 170.1 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 AEO71319.1 - 4e-06 26.9 0.0 4.7e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 LIM_bind PF01803.11 AEO71320.1 - 1.9e-80 269.4 0.0 1.9e-80 269.4 0.0 4.4 3 1 0 4 4 4 1 LIM-domain binding protein HbrB PF08539.6 AEO71321.1 - 4.4e-60 202.1 0.0 7.5e-60 201.3 0.0 1.4 1 0 0 1 1 1 1 HbrB-like Gon7 PF08738.5 AEO71322.1 - 3.4e-17 62.3 3.6 1.2e-16 60.5 2.5 1.7 1 1 0 1 1 1 1 Gon7 family DP PF08781.5 AEO71322.1 - 0.032 13.9 0.1 0.048 13.3 0.1 1.3 1 0 0 1 1 1 0 Transcription factor DP DUF4611 PF15387.1 AEO71322.1 - 0.037 14.1 2.4 0.045 13.9 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Ribosomal_60s PF00428.14 AEO71322.1 - 0.26 11.7 7.4 0.32 11.4 5.1 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Vps39_1 PF10366.4 AEO71323.1 - 7.5e-32 109.5 0.0 3.7e-31 107.3 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 AEO71323.1 - 4.3e-30 104.0 0.0 1.5e-29 102.3 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 AEO71323.1 - 1.1e-19 70.9 0.0 3.7e-19 69.2 0.0 1.7 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 AEO71323.1 - 0.0022 17.5 2.0 0.083 12.4 0.1 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_19 PF14559.1 AEO71323.1 - 0.0033 17.7 0.3 2.5 8.4 0.0 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 AEO71323.1 - 0.078 12.6 5.1 0.95 9.1 0.3 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat CLTH PF10607.4 AEO71323.1 - 0.099 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain TPR_2 PF07719.12 AEO71323.1 - 0.1 12.5 0.9 34 4.6 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Na_sulph_symp PF00939.14 AEO71324.1 - 7.9e-33 114.0 37.3 1.4e-32 113.2 25.9 1.4 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.14 AEO71324.1 - 1.7e-19 70.6 0.1 2.3e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 SPX domain CitMHS PF03600.11 AEO71324.1 - 3.7e-13 48.7 43.0 5.6e-10 38.3 17.2 2.7 1 1 2 3 3 3 3 Citrate transporter RFX_DNA_binding PF02257.10 AEO71324.1 - 0.17 12.0 0.1 0.35 11.0 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain DUF3753 PF12575.3 AEO71324.1 - 4.6 7.1 0.0 4.6 7.1 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF3753) DUF4050 PF13259.1 AEO71325.1 - 4.3e-33 113.8 0.2 1.2e-32 112.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4050) Pex14_N PF04695.8 AEO71326.1 - 1.4e-25 89.9 0.7 1.9e-24 86.2 0.0 2.5 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2673 PF10880.3 AEO71326.1 - 0.39 10.8 2.9 0.82 9.7 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) PAPA-1 PF04795.7 AEO71327.1 - 2.5e-26 92.1 1.8 2.5e-26 92.1 1.2 4.0 4 1 1 5 5 5 1 PAPA-1-like conserved region Gp_dh_C PF02800.15 AEO71329.1 - 2.6e-76 254.4 0.0 3.8e-76 253.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 AEO71329.1 - 2.8e-59 199.4 0.0 4.2e-59 198.8 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 AEO71329.1 - 0.0051 16.7 0.0 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 AEO71329.1 - 0.048 12.8 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF904 PF06005.7 AEO71330.1 - 0.52 10.6 7.2 0.39 11.0 3.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF904) IncA PF04156.9 AEO71330.1 - 0.92 9.0 8.5 1.2 8.7 5.9 1.1 1 0 0 1 1 1 0 IncA protein Hist_deacetyl PF00850.14 AEO71332.1 - 1.2e-87 294.1 0.0 1.9e-87 293.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 AEO71332.1 - 1.1e-46 158.4 0.1 1.7e-46 157.8 0.1 1.3 1 0 0 1 1 1 1 Arb2 domain F-box-like PF12937.2 AEO71333.1 - 7.3e-06 25.6 0.2 2.3e-05 24.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO71333.1 - 0.00048 19.7 0.2 0.0014 18.2 0.1 1.8 1 0 0 1 1 1 1 F-box domain Brix PF04427.13 AEO71334.1 - 5e-39 133.9 0.0 7.2e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain Ras PF00071.17 AEO71335.1 - 2.7e-62 208.9 0.2 4e-62 208.3 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO71335.1 - 3e-21 76.0 0.1 4.3e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO71335.1 - 3.3e-12 46.0 0.1 4.1e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 AEO71335.1 - 1.2e-07 31.6 0.1 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AEO71335.1 - 5.8e-05 22.6 0.1 0.00021 20.8 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 AEO71335.1 - 0.00022 21.3 0.0 0.00057 20.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 AEO71335.1 - 0.00031 19.9 0.7 0.00039 19.5 0.5 1.1 1 0 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 AEO71335.1 - 0.00088 18.4 0.1 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 AEO71335.1 - 0.0011 18.1 0.2 0.003 16.7 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 AEO71335.1 - 0.0022 17.8 0.1 0.059 13.3 0.0 2.2 2 0 0 2 2 2 1 Stage III sporulation protein D AAA_14 PF13173.1 AEO71335.1 - 0.0098 15.7 0.1 0.02 14.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 AEO71335.1 - 0.015 15.5 0.1 0.025 14.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 AEO71335.1 - 0.02 14.1 0.1 0.077 12.2 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.1 AEO71335.1 - 0.025 14.1 0.1 0.079 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 AEO71335.1 - 0.027 13.6 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 AEO71335.1 - 0.059 13.3 0.1 0.096 12.6 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 AEO71335.1 - 0.097 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 AEO71335.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Chromo PF00385.19 AEO71336.1 - 7.5e-10 38.3 0.2 2e-09 37.0 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 AEO71336.1 - 0.0015 18.3 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 ATP-cone PF03477.11 AEO71336.1 - 0.22 11.9 0.2 0.51 10.8 0.1 1.6 1 0 0 1 1 1 0 ATP cone domain DUF4066 PF13278.1 AEO71337.1 - 6.5e-28 97.0 0.0 8.7e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 AEO71337.1 - 9.7e-09 34.8 0.0 1.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family cobW PF02492.14 AEO71338.1 - 6.9e-35 120.0 0.0 9.3e-35 119.6 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 AEO71338.1 - 8e-06 24.8 1.6 0.00011 21.1 1.1 2.0 1 1 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 AEO71338.1 - 0.0061 17.3 0.1 0.013 16.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AEO71338.1 - 0.012 15.0 0.0 0.035 13.5 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.1 AEO71338.1 - 0.021 15.1 0.0 0.041 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 AEO71338.1 - 0.04 13.6 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 AEO71338.1 - 0.041 13.5 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 AEO71338.1 - 0.045 13.4 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.8 AEO71338.1 - 0.075 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus AAA_16 PF13191.1 AEO71338.1 - 0.096 12.6 0.1 0.21 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 AEO71338.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 AEO71338.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 AEO71338.1 - 0.15 11.0 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain DUF663 PF04950.7 AEO71339.1 - 1.3e-104 349.3 0.0 2e-104 348.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 AEO71339.1 - 2.5e-19 68.5 0.0 5.1e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain BING4CT PF08149.6 AEO71340.1 - 1.1e-40 136.9 0.0 3.3e-38 129.0 0.0 3.0 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 AEO71340.1 - 6.3e-08 32.2 0.0 1.2e-05 25.0 0.0 3.8 5 0 0 5 5 5 1 WD domain, G-beta repeat Co_AT_N PF12557.3 AEO71340.1 - 1.7 8.5 11.4 0.52 10.2 3.7 2.9 2 0 0 2 2 2 0 Cob(I)alamin adenosyltransferase N terminal PTH2 PF01981.11 AEO71341.1 - 4e-47 158.6 0.3 5.2e-47 158.3 0.2 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 TBX PF12598.3 AEO71341.1 - 0.049 14.0 0.0 0.082 13.2 0.0 1.3 1 0 0 1 1 1 0 T-box transcription factor PulG PF11773.3 AEO71341.1 - 0.079 12.7 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin Complex1_LYR PF05347.10 AEO71341.1 - 0.12 12.1 1.3 0.16 11.8 0.3 1.6 2 0 0 2 2 2 0 Complex 1 protein (LYR family) AAA_17 PF13207.1 AEO71342.1 - 3.2e-07 31.1 0.4 7.2e-06 26.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain PRK PF00485.13 AEO71342.1 - 4e-06 26.5 0.0 0.0071 15.9 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 AEO71342.1 - 7.5e-05 23.0 0.0 0.006 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 AEO71342.1 - 0.00012 21.7 0.0 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 AEO71342.1 - 0.0062 16.5 0.1 0.041 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Glyco_hydro_15 PF00723.16 AEO71343.1 - 6.9e-99 331.4 0.1 8.1e-99 331.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 AEO71343.1 - 6.8e-24 83.3 0.0 1.7e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain HLH PF00010.21 AEO71344.1 - 0.0014 18.2 0.0 0.0032 17.1 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FoP_duplication PF13865.1 AEO71344.1 - 0.064 13.7 2.5 1 9.8 0.0 2.4 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 SART-1 PF03343.8 AEO71345.1 - 1.1e-165 552.5 49.0 1.2e-165 552.3 34.0 1.0 1 0 0 1 1 1 1 SART-1 family DUF3328 PF11807.3 AEO71346.1 - 0.092 12.4 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) C2 PF00168.25 AEO71347.1 - 2.7e-20 71.9 0.0 1.3e-13 50.5 0.0 2.5 2 0 0 2 2 2 2 C2 domain DrrA_P4M PF14860.1 AEO71351.1 - 0.038 13.7 1.1 0.043 13.5 0.8 1.2 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain COesterase PF00135.23 AEO71352.1 - 2.2e-85 287.4 0.0 3e-85 286.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO71352.1 - 3.7e-08 33.2 1.8 1.5e-07 31.2 0.4 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO71352.1 - 0.0052 16.5 0.3 0.013 15.2 0.2 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DASH_Dad2 PF08654.5 AEO71354.1 - 9.3e-35 118.7 0.6 1.1e-34 118.4 0.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.17 AEO71354.1 - 0.032 14.2 0.7 0.05 13.6 0.3 1.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.1 AEO71354.1 - 0.062 13.7 0.5 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Shugoshin_N PF07558.6 AEO71355.1 - 2.5e-15 55.8 4.2 5.4e-15 54.8 2.9 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 AEO71355.1 - 1.4e-10 40.4 6.7 1.4e-10 40.4 4.7 4.3 4 0 0 4 4 4 1 Shugoshin C terminus AKNA PF12443.3 AEO71355.1 - 0.92 9.5 6.7 0.086 12.8 0.7 2.2 2 0 0 2 2 2 0 AT-hook-containing transcription factor Metallophos_2 PF12850.2 AEO71356.1 - 3.2e-11 43.3 0.0 3.7e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AEO71356.1 - 0.041 13.2 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Aminotran_5 PF00266.14 AEO71357.1 - 7e-27 94.1 0.0 9.2e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DevR PF01905.11 AEO71358.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 CRM1_C PF08767.6 AEO71359.1 - 3.5e-131 436.8 2.3 3.5e-131 436.8 1.6 3.2 4 1 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 AEO71359.1 - 9.9e-42 142.3 7.1 9.9e-42 142.3 4.9 3.3 4 1 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 AEO71359.1 - 4.1e-13 49.0 0.2 2.6e-12 46.4 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 AEO71359.1 - 0.038 14.3 2.7 1.1 9.6 0.0 4.4 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region DUF3385 PF11865.3 AEO71359.1 - 0.053 13.4 3.8 0.16 11.9 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) C8 PF08742.6 AEO71359.1 - 0.12 12.6 1.2 1.4 9.1 0.0 3.1 3 0 0 3 3 3 0 C8 domain SKG6 PF08693.5 AEO71360.1 - 1.6e-08 33.7 1.8 1.6e-08 33.7 1.3 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 AEO71360.1 - 0.0034 16.8 0.0 0.0068 15.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) CcmD PF04995.9 AEO71360.1 - 0.0062 16.2 1.3 0.012 15.3 0.9 1.4 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) TMEM154 PF15102.1 AEO71360.1 - 0.83 9.3 21.7 2.4e+02 1.3 15.1 2.7 1 1 0 1 1 1 0 TMEM154 protein family CytochromB561_N PF09786.4 AEO71360.1 - 1.9 6.8 16.3 2.2 6.6 11.3 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal TFIIA PF03153.8 AEO71360.1 - 3.9 7.2 12.9 5.4 6.8 9.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cpn60_TCP1 PF00118.19 AEO71361.1 - 8.8e-163 542.3 0.3 1e-162 542.1 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 AEO71362.1 - 5.6e-24 84.2 0.0 6.9e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) His_Phos_1 PF00300.17 AEO71363.1 - 6.2e-32 110.8 0.5 1.3e-31 109.8 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 AEO71363.1 - 0.00022 20.6 0.0 0.00044 19.6 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MCPVI PF02993.9 AEO71364.1 - 0.27 11.3 4.1 0.39 10.8 2.8 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Ecl1 PF12855.2 AEO71365.1 - 1.9e-08 33.4 1.7 3.5e-08 32.5 1.2 1.4 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 AEO71365.1 - 0.027 14.3 2.8 0.057 13.2 2.0 1.5 1 0 0 1 1 1 0 MYND finger Exo_endo_phos PF03372.18 AEO71368.1 - 3.4e-11 43.5 0.0 5e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zinc_ribbon_6 PF14599.1 AEO71369.1 - 6e-25 86.8 1.2 6e-25 86.8 0.9 3.9 3 1 1 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 AEO71369.1 - 4.3e-15 55.6 22.0 4.3e-15 55.6 15.2 4.4 2 1 1 3 3 3 1 CHY zinc finger zf-C3HC4_2 PF13923.1 AEO71369.1 - 2.1e-08 34.0 9.9 2.1e-08 34.0 6.9 5.3 4 1 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO71369.1 - 3.8e-08 33.0 11.7 3.8e-08 33.0 8.1 4.7 4 1 1 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.20 AEO71369.1 - 8.7e-05 22.0 10.4 8.7e-05 22.0 7.2 5.3 5 2 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO71369.1 - 9.5e-05 22.0 11.1 9.5e-05 22.0 7.7 6.4 4 2 2 6 6 6 1 zinc-RING finger domain zf-rbx1 PF12678.2 AEO71369.1 - 0.0046 17.0 13.3 0.0046 17.0 9.2 3.9 2 1 1 3 3 3 1 RING-H2 zinc finger MOZART1 PF12554.3 AEO71370.1 - 1.8e-26 91.3 1.1 2.1e-26 91.0 0.8 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.2 AEO71370.1 - 0.097 12.2 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated TPR_10 PF13374.1 AEO71370.1 - 5.5 7.0 6.3 27 4.8 2.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Spindle_Spc25 PF08234.7 AEO71371.1 - 7.2e-22 77.1 0.1 2.5e-21 75.4 0.0 2.0 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Toxin_62 PF15540.1 AEO71371.1 - 0.079 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative toxin 62 Atg14 PF10186.4 AEO71371.1 - 0.099 11.5 9.0 0.17 10.7 6.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 AEO71371.1 - 1.2 7.4 7.7 1.5 7.1 5.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.3 AEO71371.1 - 3.5 7.5 18.3 7 6.5 9.2 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Mnd1 PF03962.10 AEO71371.1 - 7.2 6.2 13.7 2.1 7.9 4.6 2.3 1 1 1 2 2 2 0 Mnd1 family Rrn6 PF10214.4 AEO71372.1 - 1.1e-74 251.9 0.0 5.1e-71 239.8 0.0 2.8 1 1 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor PITH PF06201.8 AEO71373.1 - 2.2e-47 160.6 0.0 2.6e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 PITH domain PAZ_siRNAbind PF12212.3 AEO71374.1 - 0.06 12.9 0.1 0.13 11.9 0.1 1.5 1 1 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain DUF98 PF01947.11 AEO71374.1 - 0.12 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF98) Ribosomal_L3 PF00297.17 AEO71375.1 - 1.3e-30 106.6 0.2 3.5e-30 105.2 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein L3 YkyA PF10368.4 AEO71375.1 - 0.36 10.1 3.5 0.52 9.6 2.4 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Coa1 PF08695.5 AEO71376.1 - 6.6e-38 128.8 0.0 8.7e-38 128.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Tetraspannin PF00335.15 AEO71377.1 - 0.0029 16.9 0.8 0.0031 16.8 0.0 1.6 2 0 0 2 2 2 1 Tetraspanin family DUF1191 PF06697.7 AEO71377.1 - 0.093 11.5 0.0 0.15 10.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1191) CUE PF02845.11 AEO71379.1 - 1e-13 50.4 0.0 1.9e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain Snf7 PF03357.16 AEO71380.1 - 3.6e-35 120.8 5.2 4.4e-35 120.5 3.6 1.1 1 0 0 1 1 1 1 Snf7 DUF2520 PF10728.4 AEO71380.1 - 0.0092 15.4 1.7 0.0095 15.3 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2520) HSCB_C PF07743.8 AEO71380.1 - 4 7.9 10.5 1.2 9.6 2.3 2.8 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain LXG PF04740.7 AEO71380.1 - 5.1 6.8 7.4 13 5.4 0.3 2.8 3 1 1 4 4 4 0 LXG domain of WXG superfamily DUF2293 PF10056.4 AEO71381.1 - 2.5e-28 97.8 0.0 8.6e-28 96.1 0.0 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) OB_NTP_bind PF07717.11 AEO71382.1 - 3.9e-24 84.6 0.0 7.1e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 AEO71382.1 - 2.3e-21 75.7 0.1 5.3e-21 74.5 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AEO71382.1 - 6.9e-12 45.0 0.0 1.6e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AEO71382.1 - 1.6e-05 25.0 0.0 4.8e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 AEO71382.1 - 0.00047 19.6 0.0 0.001 18.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.1 AEO71382.1 - 0.025 14.0 0.0 0.076 12.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 AEO71382.1 - 0.033 14.1 0.1 5.7 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 AEO71382.1 - 0.044 12.8 1.2 0.2 10.7 0.1 2.5 2 1 1 3 3 3 0 Zeta toxin cobW PF02492.14 AEO71382.1 - 0.067 12.6 0.1 1 8.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 AEO71382.1 - 0.094 11.5 0.1 0.31 9.9 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.1 AEO71382.1 - 0.098 12.5 0.1 0.29 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain SKG6 PF08693.5 AEO71383.1 - 0.086 12.1 3.3 0.29 10.4 1.6 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain FAD_binding_3 PF01494.14 AEO71384.1 - 0.027 13.5 0.0 0.027 13.5 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain S10_plectin PF03501.10 AEO71385.1 - 3.5e-37 126.1 0.1 4.3e-37 125.8 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Telomere_Sde2 PF13019.1 AEO71386.1 - 2.7e-44 150.7 0.1 3e-44 150.5 0.1 1.0 1 0 0 1 1 1 1 Telomere stability and silencing BNIP3 PF06553.7 AEO71387.1 - 0.002 17.5 1.4 0.0028 17.0 1.0 1.2 1 0 0 1 1 1 1 BNIP3 Telomere_Sde2 PF13019.1 AEO71387.1 - 0.11 12.2 4.6 0.18 11.4 3.2 1.4 1 0 0 1 1 1 0 Telomere stability and silencing LacI PF00356.16 AEO71387.1 - 0.12 11.9 0.1 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family REV PF00424.13 AEO71387.1 - 0.46 10.4 6.5 0.089 12.7 2.1 1.7 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) OmdA PF13376.1 AEO71387.1 - 2.9 7.6 5.4 4.4 7.0 3.8 1.3 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Nucleoplasmin PF03066.10 AEO71387.1 - 3 7.3 9.6 0.48 9.9 2.9 2.0 2 0 0 2 2 2 0 Nucleoplasmin COX6B PF02297.12 AEO71388.1 - 3.2e-18 65.5 4.4 3.8e-18 65.2 3.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 AEO71388.1 - 0.0052 16.1 0.3 0.0076 15.6 0.2 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain ketoacyl-synt PF00109.21 AEO71388.1 - 0.014 14.8 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain B12D PF06522.6 AEO71389.1 - 1.7e-10 40.4 0.0 4.1e-10 39.2 0.0 1.6 2 0 0 2 2 2 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_6 PF14259.1 AEO71390.1 - 6.4e-17 61.3 0.0 9.6e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO71390.1 - 1.9e-16 59.4 0.0 3.4e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO71390.1 - 1.2e-10 41.0 0.0 2.3e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AEO71390.1 - 0.0089 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Limkain b1 Nup35_RRM_2 PF14605.1 AEO71390.1 - 0.018 14.8 0.1 0.036 13.8 0.0 1.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 AEO71390.1 - 0.085 12.7 0.0 0.79 9.5 0.0 2.1 1 1 0 1 1 1 0 RNA binding motif WD40 PF00400.27 AEO71391.1 - 4.7e-20 70.6 5.2 0.00022 21.0 0.0 7.2 6 1 1 7 7 7 4 WD domain, G-beta repeat SRA1 PF07304.6 AEO71391.1 - 9e-08 31.9 0.0 9e-08 31.9 0.0 2.8 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 AEO71391.1 - 7.6e-07 29.1 0.1 1.8e-06 27.9 0.1 1.6 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Ndc80_HEC PF03801.8 AEO71391.1 - 0.17 11.2 0.2 0.32 10.4 0.1 1.4 1 0 0 1 1 1 0 HEC/Ndc80p family GET2 PF08690.5 AEO71392.1 - 5.7e-18 65.2 0.0 9.2e-18 64.5 0.0 1.3 1 1 0 1 1 1 1 GET complex subunit GET2 HATPase_c PF02518.21 AEO71393.1 - 1.6e-23 82.5 0.2 2.9e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AEO71393.1 - 1.4e-21 76.2 0.1 4.2e-21 74.7 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 AEO71393.1 - 2.1e-20 72.6 1.0 1e-12 47.9 0.2 3.5 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 AEO71393.1 - 2.3e-13 50.4 0.0 9e-08 32.4 0.0 3.4 2 1 0 2 2 2 2 PAS domain PAS PF00989.19 AEO71393.1 - 6.1e-09 35.6 0.0 3.3e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 AEO71393.1 - 1.1e-08 35.1 0.1 2.8e-07 30.5 0.1 2.9 2 0 0 2 2 2 1 PAS fold Response_reg PF00072.19 AEO71393.1 - 0.0045 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_8 PF13188.1 AEO71393.1 - 0.054 13.3 0.0 12 5.9 0.0 2.6 2 0 0 2 2 2 0 PAS domain Ssl1 PF04056.9 AEO71394.1 - 1.2e-58 197.9 0.0 1.5e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 AEO71394.1 - 2e-08 34.5 0.0 3.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyoxalase PF00903.20 AEO71395.1 - 5e-22 78.2 0.1 1.3e-14 54.2 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 AEO71395.1 - 2.7e-13 50.4 0.0 2.1e-07 31.5 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 AEO71395.1 - 3.9e-13 49.3 0.1 2.4e-06 27.5 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 AEO71395.1 - 1.8e-05 24.7 0.1 0.05 13.5 0.0 3.0 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 AEO71395.1 - 0.0013 18.6 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF2283 PF10049.4 AEO71395.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) TPR_11 PF13414.1 AEO71396.1 - 0.0043 16.6 0.2 0.2 11.3 0.1 2.4 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.1 AEO71396.1 - 0.031 14.4 0.1 0.36 11.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 AEO71396.1 - 0.097 13.0 0.6 0.59 10.5 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 AEO71396.1 - 0.25 12.0 2.9 0.21 12.2 0.6 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L27e PF01777.13 AEO71397.1 - 2.1e-37 127.1 3.8 2.7e-37 126.7 2.6 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 AEO71397.1 - 0.013 15.1 0.2 0.04 13.6 0.1 1.8 1 0 0 1 1 1 0 KOW motif DUF1922 PF09082.5 AEO71397.1 - 0.083 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) ECM11 PF15463.1 AEO71397.1 - 0.22 11.8 1.5 0.24 11.6 0.2 1.6 2 0 0 2 2 2 0 Extracellular mutant protein 11 TPT PF03151.11 AEO71398.1 - 2.4e-30 105.2 15.5 2.4e-30 105.2 10.7 2.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 AEO71398.1 - 0.00086 18.3 27.2 0.021 13.7 5.4 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 AEO71398.1 - 0.036 14.1 39.8 0.17 11.9 10.8 2.9 3 0 0 3 3 3 0 EamA-like transporter family NAD_binding_8 PF13450.1 AEO71399.1 - 2.4e-09 37.0 0.0 5e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 AEO71399.1 - 3.2e-07 29.8 0.0 6.3e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 AEO71399.1 - 1.4e-05 25.2 0.1 3.1e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO71399.1 - 0.003 17.4 0.0 0.036 13.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 AEO71399.1 - 0.012 14.6 0.1 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 AEO71399.1 - 0.029 12.8 0.0 0.047 12.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 AEO71399.1 - 0.037 13.7 0.1 1.7 8.4 0.0 2.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 AEO71399.1 - 0.057 12.4 0.5 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Thi4 family DAO PF01266.19 AEO71399.1 - 0.083 11.7 0.0 0.31 9.8 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 AEO71399.1 - 0.1 11.4 0.3 0.21 10.4 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.2 AEO71399.1 - 0.12 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HATPase_c PF02518.21 AEO71400.1 - 1e-28 99.2 0.0 5.5e-28 96.9 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 AEO71400.1 - 3e-21 75.5 0.2 1.2e-20 73.5 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 AEO71400.1 - 1.3e-19 69.9 0.5 5e-19 68.0 0.3 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 AEO71400.1 - 5.4e-16 59.1 0.2 3e-15 56.6 0.1 2.4 1 0 0 1 1 1 1 AAA ATPase domain GAF_2 PF13185.1 AEO71400.1 - 5.9e-10 39.8 0.0 2e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 AEO71400.1 - 1.3e-09 38.2 0.0 3.1e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 AEO71400.1 - 8.3e-09 34.9 0.0 1.9e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71400.1 - 2.5e-05 23.4 0.0 4.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HATPase_c_3 PF13589.1 AEO71400.1 - 0.00011 21.8 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_11 PF13414.1 AEO71400.1 - 0.00097 18.7 11.6 0.0083 15.7 0.7 4.5 4 1 1 5 5 5 1 TPR repeat NACHT PF05729.7 AEO71400.1 - 0.0033 17.0 0.1 1.9 8.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 AEO71400.1 - 0.0036 17.4 0.0 1.5 8.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain TPR_12 PF13424.1 AEO71400.1 - 0.0057 16.5 10.8 0.22 11.4 0.7 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO71400.1 - 0.014 15.1 0.1 0.45 10.4 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat NB-ARC PF00931.17 AEO71400.1 - 0.13 11.1 0.0 0.4 9.4 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain TPR_2 PF07719.12 AEO71400.1 - 0.35 10.9 3.8 32 4.7 0.0 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat Zip PF02535.17 AEO71401.1 - 0.058 12.3 4.4 0.078 11.9 3.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter RabGAP-TBC PF00566.13 AEO71404.1 - 1.3e-32 113.0 0.0 1.3e-32 113.0 0.0 3.4 3 1 1 4 4 4 1 Rab-GTPase-TBC domain DIL PF01843.14 AEO71405.1 - 5.6e-21 74.3 1.6 8.1e-19 67.4 1.1 2.5 1 1 0 1 1 1 1 DIL domain Ank_2 PF12796.2 AEO71405.1 - 1.1e-18 67.3 0.3 3.1e-18 65.8 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AEO71405.1 - 1.5e-16 60.4 0.5 5.1e-07 30.0 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 AEO71405.1 - 7.8e-16 56.9 0.1 5.7e-06 25.8 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 AEO71405.1 - 1.2e-12 47.5 0.1 4.2e-08 33.1 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO71405.1 - 1.8e-09 36.9 0.1 0.033 14.4 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat DUF605 PF04652.11 AEO71405.1 - 0.00033 20.1 3.5 0.00063 19.2 2.4 1.5 1 0 0 1 1 1 1 Vta1 like Herpes_TAF50 PF03326.8 AEO71405.1 - 0.17 10.7 12.0 0.29 10.0 8.3 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Allantoicase PF03561.10 AEO71406.1 - 1.6e-109 362.0 0.1 2e-58 196.1 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Cytochrom_B561 PF03188.11 AEO71407.1 - 4.8e-17 62.0 4.2 8.7e-17 61.2 2.9 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.1 AEO71407.1 - 0.11 12.5 13.8 0.77 9.7 8.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) PepSY_TM_1 PF13172.1 AEO71407.1 - 0.15 11.8 0.4 0.15 11.8 0.2 2.9 3 0 0 3 3 3 0 PepSY-associated TM helix DUF588 PF04535.7 AEO71407.1 - 0.17 11.4 4.4 0.27 10.8 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF588) Ferric_reduct PF01794.14 AEO71407.1 - 4.9 7.2 12.9 0.82 9.7 5.4 2.1 2 1 0 2 2 2 0 Ferric reductase like transmembrane component Chs3p PF12271.3 AEO71408.1 - 1.4e-105 352.4 3.1 1.6e-105 352.2 2.2 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Sugar_tr PF00083.19 AEO71409.1 - 1.8e-94 316.8 9.2 2.3e-94 316.5 6.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO71409.1 - 1.9e-26 92.6 27.9 5.8e-19 68.0 4.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO71409.1 - 8.5e-10 37.5 16.9 4e-06 25.5 2.2 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein DUF791 PF05631.9 AEO71409.1 - 0.018 13.7 0.4 0.018 13.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF791) TRI12 PF06609.8 AEO71409.1 - 0.42 8.7 6.2 0.3 9.2 3.1 1.5 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Complex1_LYR PF05347.10 AEO71410.1 - 1e-05 25.1 0.6 1e-05 25.1 0.4 2.1 1 1 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AEO71410.1 - 0.026 14.7 3.4 0.04 14.1 2.3 1.6 1 1 0 1 1 1 0 Complex1_LYR-like Mito_carr PF00153.22 AEO71411.1 - 1.6e-45 152.7 7.2 5.8e-17 61.1 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein PTS_EIIC PF02378.13 AEO71411.1 - 0.05 12.4 0.8 1.9 7.2 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase system, EIIC SpoIIIAH PF12685.2 AEO71411.1 - 0.33 10.4 3.5 0.47 9.9 2.4 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein AAA PF00004.24 AEO71412.1 - 3.7e-86 286.0 0.0 2.4e-46 157.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AEO71412.1 - 2.3e-14 53.0 0.0 1.2e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 AEO71412.1 - 1.6e-10 40.8 0.8 3e-05 23.7 0.1 3.9 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AEO71412.1 - 8e-10 38.9 2.2 0.0045 17.1 0.0 4.8 3 2 0 3 3 2 2 AAA domain AAA_16 PF13191.1 AEO71412.1 - 1.2e-09 38.4 12.4 8.3e-05 22.6 0.0 5.0 4 2 0 4 4 4 2 AAA ATPase domain AAA_14 PF13173.1 AEO71412.1 - 4.6e-09 36.2 0.0 0.0038 17.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 AEO71412.1 - 6.6e-09 36.6 3.4 0.0011 19.7 0.0 3.9 2 1 1 3 3 2 2 AAA domain AAA_2 PF07724.9 AEO71412.1 - 8.2e-09 35.6 0.1 0.0003 20.7 0.0 3.7 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 AEO71412.1 - 7e-07 28.5 0.0 0.0037 16.3 0.0 2.9 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 AEO71412.1 - 7.9e-07 28.1 0.1 0.012 14.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 AEO71412.1 - 1.9e-06 27.8 11.1 0.00059 19.7 0.0 3.8 5 1 0 5 5 2 2 AAA domain RNA_helicase PF00910.17 AEO71412.1 - 1.9e-06 27.9 0.0 0.089 12.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 AEO71412.1 - 2.1e-06 28.0 0.1 0.042 14.1 0.0 3.1 2 1 1 3 3 2 2 ABC transporter IstB_IS21 PF01695.12 AEO71412.1 - 4e-06 26.3 0.8 0.061 12.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 AEO71412.1 - 4.1e-06 26.8 5.1 0.044 13.7 0.0 4.0 3 1 0 3 3 3 2 AAA domain Vps4_C PF09336.5 AEO71412.1 - 1.2e-05 25.0 0.0 0.00039 20.2 0.0 2.9 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.8 AEO71412.1 - 2.9e-05 23.1 0.0 0.014 14.3 0.0 2.6 3 0 0 3 3 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 AEO71412.1 - 5.4e-05 22.7 0.1 0.41 10.0 0.0 3.0 3 0 0 3 3 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.16 AEO71412.1 - 5.6e-05 22.3 0.5 0.094 11.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 AEO71412.1 - 6.4e-05 22.6 1.8 0.068 12.8 0.2 3.5 4 0 0 4 4 3 1 NACHT domain AAA_25 PF13481.1 AEO71412.1 - 0.00011 21.7 9.5 1.3 8.3 0.2 4.7 2 2 2 4 4 4 1 AAA domain NB-ARC PF00931.17 AEO71412.1 - 0.00011 21.2 0.1 0.15 10.9 0.1 2.4 2 0 0 2 2 2 2 NB-ARC domain Rad17 PF03215.10 AEO71412.1 - 0.00013 20.8 0.0 0.28 9.7 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 AEO71412.1 - 0.00014 22.1 9.1 0.22 11.8 0.0 4.0 4 0 0 4 4 3 2 AAA domain Sigma54_activ_2 PF14532.1 AEO71412.1 - 0.00019 21.4 0.2 0.16 12.0 0.0 3.1 4 0 0 4 4 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 AEO71412.1 - 0.00064 19.4 1.1 0.039 13.6 0.0 4.3 4 1 0 4 4 3 2 Part of AAA domain AAA_3 PF07726.6 AEO71412.1 - 0.001 18.6 0.0 1.8 8.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 AEO71412.1 - 0.0016 17.9 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain KaiC PF06745.8 AEO71412.1 - 0.0023 17.0 0.3 1.9 7.5 0.0 2.6 3 0 0 3 3 2 1 KaiC Viral_helicase1 PF01443.13 AEO71412.1 - 0.0025 17.3 0.0 0.57 9.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase SKI PF01202.17 AEO71412.1 - 0.0027 17.5 3.6 0.66 9.8 0.0 3.0 3 0 0 3 3 2 2 Shikimate kinase AAA_29 PF13555.1 AEO71412.1 - 0.003 17.0 0.0 0.11 12.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 AEO71412.1 - 0.0037 16.9 1.3 2.8 7.6 0.1 3.0 3 0 0 3 3 2 1 NTPase UPF0079 PF02367.12 AEO71412.1 - 0.0038 16.8 1.6 0.47 10.0 0.0 2.8 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 AEO71412.1 - 0.0038 16.9 0.0 5.2 6.6 0.0 3.1 2 1 1 3 3 3 0 Archaeal ATPase AAA_24 PF13479.1 AEO71412.1 - 0.0047 16.5 0.7 4.3 6.8 0.1 3.0 3 0 0 3 3 3 0 AAA domain Bac_DnaA PF00308.13 AEO71412.1 - 0.0068 16.0 0.1 1.6 8.3 0.0 2.9 3 0 0 3 3 2 1 Bacterial dnaA protein PduV-EutP PF10662.4 AEO71412.1 - 0.0097 15.3 0.0 0.6 9.5 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 AEO71412.1 - 0.019 14.1 0.7 14 4.8 0.0 3.2 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit ResIII PF04851.10 AEO71412.1 - 0.021 14.6 0.0 1.6 8.5 0.0 2.9 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 AEO71412.1 - 0.05 13.1 1.2 3.9 6.9 0.0 2.9 3 1 0 3 3 2 0 AAA domain Parvo_NS1 PF01057.12 AEO71412.1 - 0.12 11.2 0.3 4.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF258 PF03193.11 AEO71412.1 - 0.13 11.3 0.1 1.2 8.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 AEO71412.1 - 4.4 7.5 7.1 1.5 9.0 0.2 3.0 3 0 0 3 3 3 0 AAA domain Cytochrom_C PF00034.16 AEO71413.1 - 9.3e-11 42.4 0.1 1.4e-10 41.8 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 AEO71413.1 - 3e-09 36.8 2.9 1.5e-08 34.6 2.0 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 AEO71413.1 - 0.00042 19.7 0.2 0.0036 16.7 0.1 2.2 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.9 AEO71413.1 - 0.036 14.3 0.0 0.064 13.5 0.0 1.5 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase RNase_PH PF01138.16 AEO71415.1 - 3.1e-15 56.6 0.0 1.3e-14 54.6 0.0 2.1 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AEO71415.1 - 0.003 17.4 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF533 PF04391.7 AEO71415.1 - 1 8.6 10.6 0.79 9.0 5.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF533) Pex14_N PF04695.8 AEO71415.1 - 7.5 6.6 9.9 8.5 6.4 1.0 2.7 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 AEO71415.1 - 8 4.5 19.9 10 4.1 13.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PARP PF00644.15 AEO71416.1 - 1e-12 47.9 0.0 1.9e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 AEO71416.1 - 4.8e-08 32.5 0.0 9.7e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO71416.1 - 0.034 13.8 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic E2 family B DUF666 PF05006.7 AEO71416.1 - 0.088 12.7 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF666) COG5 PF10392.4 AEO71417.1 - 6.7e-05 22.8 1.3 0.00068 19.5 0.0 2.8 3 0 0 3 3 3 1 Golgi transport complex subunit 5 ATE_C PF04377.10 AEO71418.1 - 6.5e-43 145.8 0.0 1.1e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 AEO71418.1 - 3.5e-16 58.7 0.4 7e-16 57.8 0.3 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus NUDIX PF00293.23 AEO71419.1 - 2.9e-20 72.2 1.2 3.5e-20 72.0 0.9 1.1 1 0 0 1 1 1 1 NUDIX domain ATP-synt_8 PF00895.15 AEO71421.1 - 0.011 15.8 0.2 0.018 15.2 0.1 1.2 1 0 0 1 1 1 0 ATP synthase protein 8 DUF1189 PF06691.6 AEO71421.1 - 0.018 14.4 0.0 0.018 14.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Ribosomal_S5 PF00333.15 AEO71422.1 - 5.4e-12 45.2 0.3 9e-12 44.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DASH_Dad3 PF08656.5 AEO71423.1 - 1.3e-27 95.3 0.0 1.5e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 CorA PF01544.13 AEO71424.1 - 0.31 10.0 0.0 0.47 9.4 0.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.20 AEO71425.1 - 2.9e-71 239.6 0.0 5.6e-71 238.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71425.1 - 1.3e-30 106.3 0.0 2.7e-22 79.0 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AEO71425.1 - 9.7e-07 28.0 0.0 0.32 9.9 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.9 AEO71425.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO71425.1 - 0.053 13.2 0.0 1.2 8.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family SPX PF03105.14 AEO71426.1 - 0.0083 15.9 5.5 0.011 15.5 2.6 2.0 1 1 0 1 1 1 1 SPX domain zf-C2H2_4 PF13894.1 AEO71426.1 - 0.039 14.2 0.9 0.17 12.2 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short PF00106.20 AEO71427.1 - 7.6e-18 64.9 2.5 1.1e-17 64.4 1.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO71427.1 - 2.3e-08 34.1 0.0 2.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO71427.1 - 7.7e-08 32.1 0.4 1.2e-07 31.5 0.3 1.4 1 1 0 1 1 1 1 KR domain zf-CCCH PF00642.19 AEO71428.1 - 4.5e-06 26.2 0.9 4.5e-06 26.2 0.6 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AEO71428.1 - 0.13 12.3 9.5 0.32 11.0 0.1 2.9 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Ost4 PF10215.4 AEO71429.1 - 8.9e-18 63.4 0.8 1.1e-17 63.2 0.5 1.1 1 0 0 1 1 1 1 Oligosaccaryltransferase RRM_1 PF00076.17 AEO71430.1 - 2.1e-15 56.0 0.0 3.8e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO71430.1 - 1.4e-12 47.4 0.0 2.2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO71430.1 - 2e-07 30.7 0.0 3.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 AEO71430.1 - 1.1e-05 25.8 1.7 1.1e-05 25.8 1.2 3.0 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 FXR1P_C PF12235.3 AEO71430.1 - 0.59 10.2 11.3 2.8 8.0 0.8 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein C terminal Snf7 PF03357.16 AEO71431.1 - 4e-23 81.6 1.2 4e-23 81.6 0.8 2.0 2 0 0 2 2 2 1 Snf7 DUF3484 PF11983.3 AEO71431.1 - 1.2 9.9 5.5 0.49 11.2 1.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3484) CS PF04969.11 AEO71432.1 - 2.5e-09 37.5 0.0 4e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 CS domain SDA1 PF05285.7 AEO71432.1 - 0.39 9.9 9.9 0.54 9.4 6.8 1.2 1 0 0 1 1 1 0 SDA1 Mito_fiss_reg PF05308.6 AEO71433.1 - 3.5 6.9 6.9 4.1 6.6 4.8 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4472 PF14739.1 AEO71435.1 - 0.24 11.8 3.6 0.37 11.2 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) PIG-H PF10181.4 AEO71437.1 - 8.6e-21 73.3 0.0 1.7e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DUF1669 PF07894.7 AEO71437.1 - 7.8 5.5 5.9 4.2 6.4 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1669) PseudoU_synth_1 PF01416.15 AEO71438.1 - 9.1e-28 96.7 0.0 1.1e-20 73.9 0.0 2.7 2 1 0 2 2 2 2 tRNA pseudouridine synthase SAND PF01342.16 AEO71438.1 - 0.0039 16.8 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 SAND domain Rrn6 PF10214.4 AEO71438.1 - 8.8 4.2 8.9 12 3.8 6.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Ras PF00071.17 AEO71439.1 - 1.2e-14 54.0 0.0 4.2e-08 32.7 0.0 2.3 2 1 0 2 2 2 2 Ras family Miro PF08477.8 AEO71439.1 - 7.4e-05 23.2 0.0 0.00022 21.7 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arch_ATPase PF01637.13 AEO71439.1 - 0.019 14.6 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Arf PF00025.16 AEO71439.1 - 0.027 13.7 0.0 4 6.6 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family G-alpha PF00503.15 AEO71439.1 - 0.079 11.6 0.2 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 G-protein alpha subunit RNA_pol_Rpb4 PF03874.11 AEO71440.1 - 2.2e-26 92.1 0.6 2.5e-26 91.9 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Pribosyl_synth PF14572.1 AEO71441.1 - 5.4e-38 130.5 1.1 5.1e-33 114.3 0.3 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 AEO71441.1 - 1.9e-29 101.7 0.0 4.9e-29 100.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 AEO71441.1 - 2.7e-12 46.5 0.1 6.4e-12 45.2 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AEO71441.1 - 0.002 17.3 0.1 0.0034 16.6 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AviRa PF11599.3 AEO71441.1 - 0.047 12.7 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa SLAC1 PF03595.12 AEO71442.1 - 7.2e-49 166.2 34.1 8.1e-49 166.0 23.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3609 PF12259.3 AEO71442.1 - 0.21 10.1 0.0 0.37 9.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) RasGEF PF00617.14 AEO71443.1 - 3.1e-44 150.9 0.1 4.3e-44 150.4 0.1 1.2 1 0 0 1 1 1 1 RasGEF domain Miro PF08477.8 AEO71443.1 - 6.3e-15 55.7 0.0 1.4e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein RasGEF_N PF00618.15 AEO71443.1 - 3e-10 40.1 0.0 5.7e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.17 AEO71443.1 - 0.0012 18.2 0.0 0.031 13.6 0.0 2.5 2 1 0 2 2 2 1 Ras family FtsK_SpoIIIE PF01580.13 AEO71443.1 - 0.0018 17.7 0.0 0.21 11.0 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 AEO71443.1 - 0.005 16.9 0.0 0.11 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AEO71443.1 - 0.006 16.5 0.8 0.16 11.9 0.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 AEO71443.1 - 0.017 15.9 0.0 0.16 12.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 AEO71443.1 - 0.017 14.2 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IIGP PF05049.8 AEO71443.1 - 0.018 13.8 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_28 PF13521.1 AEO71443.1 - 0.038 13.9 0.2 0.091 12.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.18 AEO71443.1 - 0.049 13.5 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 AEO71443.1 - 0.058 13.2 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Dynamin family G-alpha PF00503.15 AEO71443.1 - 0.075 11.7 0.0 0.42 9.2 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.1 AEO71443.1 - 0.081 12.7 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 AEO71443.1 - 0.18 11.2 0.0 20 4.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 AEO71443.1 - 0.21 11.1 0.0 0.65 9.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 AEO71443.1 - 0.21 11.1 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AEO71443.1 - 0.21 11.8 0.0 0.99 9.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter MobB PF03205.9 AEO71443.1 - 0.32 10.7 0.0 0.74 9.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B zf-HIT PF04438.11 AEO71445.1 - 3.1e-12 45.9 10.7 4.8e-12 45.2 7.4 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 AEO71445.1 - 2e-05 24.3 7.3 3.5e-05 23.5 5.0 1.4 1 0 0 1 1 1 1 MYND finger YL1_C PF08265.6 AEO71445.1 - 0.11 12.0 1.0 0.2 11.2 0.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain zf-Mss51 PF13824.1 AEO71445.1 - 3.5 7.5 7.0 9.3 6.1 4.9 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Nfu_N PF08712.6 AEO71446.1 - 9.9e-30 102.0 0.0 2.2e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 AEO71446.1 - 5.4e-21 74.1 0.1 9.5e-21 73.3 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain PSP1 PF04468.7 AEO71448.1 - 2.2e-31 107.6 0.8 3.6e-31 106.9 0.5 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Rotavirus_VP3 PF06929.6 AEO71448.1 - 0.41 8.4 0.5 0.63 7.8 0.3 1.2 1 0 0 1 1 1 0 Rotavirus VP3 protein PMC2NT PF08066.7 AEO71449.1 - 0.018 15.2 0.1 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 PMC2NT (NUC016) domain DUF848 PF05852.6 AEO71449.1 - 0.23 11.3 2.9 0.57 10.0 0.1 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Ribosomal_L15e PF00827.12 AEO71450.1 - 2.1e-92 307.9 12.5 2.4e-92 307.7 8.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 PUF PF00806.14 AEO71451.1 - 4.1e-61 199.1 11.1 9.2e-08 31.1 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat TylF PF05711.6 AEO71451.1 - 0.051 12.6 0.1 0.099 11.7 0.1 1.4 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) RNA_pol_Rpb2_6 PF00562.23 AEO71453.1 - 3.6e-112 374.9 0.0 5e-112 374.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AEO71453.1 - 2.8e-32 111.3 0.0 5.3e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 AEO71453.1 - 1.5e-29 102.0 0.2 3.3e-29 100.9 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 AEO71453.1 - 2e-28 99.0 0.0 5.7e-28 97.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 AEO71453.1 - 2.8e-20 71.8 0.0 5.8e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 AEO71453.1 - 6.6e-20 70.6 0.0 1.6e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 AEO71453.1 - 9e-14 51.1 0.2 2.8e-13 49.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF3485 PF11984.3 AEO71455.1 - 0.056 12.5 0.1 0.056 12.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) Carn_acyltransf PF00755.15 AEO71457.1 - 2.6e-168 560.8 0.0 3.7e-152 507.4 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase SpaB_C PF14028.1 AEO71459.1 - 0.0042 16.6 2.1 0.0046 16.5 1.4 1.1 1 0 0 1 1 1 1 SpaB C-terminal domain SET PF00856.23 AEO71459.1 - 0.012 15.9 0.1 0.045 14.0 0.0 1.9 2 0 0 2 2 2 0 SET domain DUF3275 PF11679.3 AEO71459.1 - 0.032 13.8 2.2 0.044 13.3 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Ras PF00071.17 AEO71461.1 - 1.5e-65 219.4 0.5 1.8e-65 219.2 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO71461.1 - 1.2e-21 77.4 0.0 1.7e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO71461.1 - 2.8e-16 59.2 0.1 3.3e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AEO71461.1 - 1.3e-05 24.7 0.2 2.6e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AEO71461.1 - 1.7e-05 24.0 0.1 2.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AEO71461.1 - 7.1e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 AEO71461.1 - 0.00042 19.5 0.0 0.0007 18.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 AEO71461.1 - 0.00063 19.0 0.1 0.0045 16.2 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.24 AEO71461.1 - 0.0012 19.0 0.1 0.088 13.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO71461.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.6 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 AEO71461.1 - 0.0094 15.1 0.0 0.025 13.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 AEO71461.1 - 0.018 15.0 0.1 0.066 13.2 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 AEO71461.1 - 0.024 14.5 0.1 0.076 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AEO71461.1 - 0.038 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 AEO71461.1 - 0.044 12.7 0.0 0.21 10.5 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_5 PF07728.9 AEO71461.1 - 0.059 13.0 0.0 0.098 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 AEO71461.1 - 0.087 13.1 0.0 0.14 12.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 AEO71461.1 - 0.094 12.1 0.1 0.95 8.9 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PBP1_TM PF14812.1 AEO71462.1 - 5 7.5 7.4 0.93 9.8 2.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 AEO71463.1 - 4e-16 58.1 20.1 0.00011 21.9 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF627 PF04781.7 AEO71463.1 - 0.067 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Sigma70_r1_2 PF00140.15 AEO71463.1 - 0.079 12.6 0.4 0.14 11.8 0.3 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 WD40 PF00400.27 AEO71464.1 - 1e-23 82.2 5.4 1.3e-08 34.3 0.0 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat DUF3639 PF12341.3 AEO71464.1 - 1.1e-09 38.0 0.5 1.1e-09 38.0 0.4 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3639) eIF2A PF08662.6 AEO71464.1 - 4e-05 23.3 0.0 0.003 17.2 0.0 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 AEO71464.1 - 0.00052 18.9 0.0 0.0011 17.8 0.0 1.5 1 1 0 1 1 1 1 Coatomer WD associated region IKI3 PF04762.7 AEO71464.1 - 0.00053 17.9 0.0 0.001 17.0 0.0 1.4 1 0 0 1 1 1 1 IKI3 family Myc_N PF01056.13 AEO71464.1 - 0.0093 15.1 1.8 0.016 14.3 1.2 1.4 1 0 0 1 1 1 1 Myc amino-terminal region Pox_Ag35 PF03286.9 AEO71464.1 - 0.013 15.0 3.0 0.021 14.3 2.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PD40 PF07676.7 AEO71464.1 - 0.026 14.1 0.6 74 3.1 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat BUD22 PF09073.5 AEO71464.1 - 0.28 10.1 12.5 0.45 9.5 8.6 1.2 1 0 0 1 1 1 0 BUD22 Nucleoplasmin PF03066.10 AEO71464.1 - 1.5 8.3 10.2 0.049 13.1 2.0 2.2 2 0 0 2 2 2 0 Nucleoplasmin DUF1754 PF08555.5 AEO71464.1 - 1.6 9.4 8.3 2.9 8.5 5.8 1.4 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) FAM176 PF14851.1 AEO71464.1 - 1.7 8.3 3.8 3.2 7.3 2.7 1.4 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.8 AEO71464.1 - 2 8.0 8.4 4.1 6.9 5.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region HSF_DNA-bind PF00447.12 AEO71465.1 - 2.6e-36 123.9 0.4 4.8e-36 123.0 0.3 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding FTA2 PF13095.1 AEO71467.1 - 1.1e-38 132.9 0.0 1.5e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 MFS_1 PF07690.11 AEO71468.1 - 3.4e-36 124.6 53.5 3.4e-36 124.6 37.1 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO71468.1 - 2.2e-06 26.5 15.2 2.2e-06 26.5 10.5 3.3 3 0 0 3 3 3 2 Sugar (and other) transporter UNC-93 PF05978.11 AEO71468.1 - 2.2 7.7 12.1 0.023 14.1 1.4 2.9 3 1 0 3 3 3 0 Ion channel regulatory protein UNC-93 Fungal_trans PF04082.13 AEO71469.1 - 1.5e-12 46.9 0.1 2.6e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 AEO71470.1 - 1e-40 139.5 19.6 1e-40 139.5 13.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO71470.1 - 3.3e-11 42.4 19.1 6e-11 41.5 6.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 AEO71470.1 - 1.9e-08 33.0 3.8 1.9e-08 33.0 2.6 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fructosamin_kin PF03881.9 AEO71471.1 - 5.3e-26 91.2 0.0 6.6e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 AEO71471.1 - 0.0051 16.5 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family NACHT PF05729.7 AEO71472.1 - 9.2e-05 22.1 0.0 0.00023 20.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 AEO71472.1 - 0.00026 21.1 0.0 0.0012 19.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain WD40 PF00400.27 AEO71472.1 - 0.0043 16.8 2.1 12 5.9 0.1 5.6 5 0 0 5 5 5 1 WD domain, G-beta repeat AAA_16 PF13191.1 AEO71472.1 - 0.023 14.6 0.0 0.076 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain PQQ_2 PF13360.1 AEO71472.1 - 0.064 12.7 0.0 1.4 8.3 0.0 2.6 3 0 0 3 3 3 0 PQQ-like domain RNA_helicase PF00910.17 AEO71472.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF3074 PF11274.3 AEO71473.1 - 9.6e-36 123.1 0.0 3.1e-35 121.4 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) SAGA-Tad1 PF12767.2 AEO71473.1 - 0.0064 16.1 0.2 0.01 15.5 0.2 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit ATP-grasp_2 PF08442.5 AEO71474.1 - 7e-79 263.8 0.4 7e-79 263.8 0.3 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 AEO71474.1 - 1.1e-26 93.3 0.5 2e-26 92.4 0.3 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 AEO71474.1 - 1.7e-09 37.2 0.2 3.6e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 AEO71474.1 - 0.00042 19.9 0.7 0.0077 15.8 0.2 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 AEO71474.1 - 0.00097 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Peripla_BP_2 PF01497.13 AEO71474.1 - 0.027 13.6 0.1 0.051 12.6 0.1 1.4 1 0 0 1 1 1 0 Periplasmic binding protein RimK PF08443.6 AEO71474.1 - 0.054 12.9 0.0 0.6 9.5 0.0 2.4 1 1 2 3 3 3 0 RimK-like ATP-grasp domain DUF2034 PF10356.4 AEO71475.1 - 0.25 10.5 0.0 0.41 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) DUF1387 PF07139.6 AEO71476.1 - 1.3 8.5 6.2 1.6 8.2 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) RabGAP-TBC PF00566.13 AEO71477.1 - 3e-48 164.1 0.0 5.3e-46 156.7 0.0 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain CCDC155 PF14662.1 AEO71477.1 - 0.012 15.1 7.7 0.012 15.1 5.3 2.9 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 HALZ PF02183.13 AEO71477.1 - 0.019 14.6 28.1 0.14 11.8 0.2 5.1 4 1 1 5 5 5 0 Homeobox associated leucine zipper DUF972 PF06156.8 AEO71477.1 - 1.1 9.6 24.7 0.034 14.4 2.9 3.4 3 1 1 4 4 2 0 Protein of unknown function (DUF972) DUF1640 PF07798.6 AEO71477.1 - 2 8.4 15.0 9.1 6.2 10.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DivIVA PF05103.8 AEO71477.1 - 2.1 8.4 22.4 1.3 9.1 3.5 3.8 3 1 1 4 4 4 0 DivIVA protein IFP_35_N PF07334.8 AEO71477.1 - 2.1 8.3 13.3 3 7.8 1.7 3.1 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Cep57_CLD_2 PF14197.1 AEO71477.1 - 2.4 8.1 26.6 1.2 9.1 6.8 3.4 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 FUSC PF04632.7 AEO71477.1 - 2.6 6.3 7.9 5.2 5.3 5.5 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.3 AEO71477.1 - 4.8 7.0 33.7 0.049 13.5 5.5 3.4 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding DUF4201 PF13870.1 AEO71477.1 - 5.7 6.3 24.7 1.2 8.5 13.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) TBPIP PF07106.8 AEO71477.1 - 5.9 6.4 20.2 8 5.9 5.9 2.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Microtub_assoc PF07989.6 AEO71477.1 - 8.2 6.3 24.3 0.055 13.2 2.6 3.6 3 1 0 4 4 4 0 Microtubule associated Ribosomal_S8e PF01201.17 AEO71478.1 - 1.8e-48 164.0 0.9 2.1e-48 163.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e DUF913 PF06025.7 AEO71479.1 - 2.1e-119 398.6 0.0 2.1e-119 398.6 0.0 4.5 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) HECT PF00632.20 AEO71479.1 - 4e-99 331.7 0.1 4.9e-98 328.1 0.0 2.8 4 0 0 4 4 4 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 AEO71479.1 - 1.4e-93 313.8 0.0 1.4e-93 313.8 0.0 3.6 4 0 0 4 4 4 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 AEO71479.1 - 7.9e-33 112.6 10.4 7.9e-33 112.6 7.2 5.0 3 2 1 4 4 4 1 Domain of unknown function (DUF4414) Ribosomal_S6e PF01092.14 AEO71480.1 - 1.2e-62 209.1 0.1 2.6e-62 208.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e EF-1_beta_acid PF10587.4 AEO71480.1 - 1.1 9.4 4.3 2.8 8.1 3.0 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Diphthamide_syn PF01866.12 AEO71481.1 - 1.2e-111 372.8 0.0 1.4e-111 372.6 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Aldose_epim PF01263.15 AEO71482.1 - 2.8e-41 141.5 0.1 3.7e-41 141.1 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase ATP-synt_ab PF00006.20 AEO71483.1 - 3.6e-61 206.3 0.0 4.6e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AEO71483.1 - 2.4e-16 60.2 0.0 4.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AEO71483.1 - 3.3e-11 43.2 1.0 6.7e-11 42.2 0.7 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 AEO71483.1 - 0.00074 19.3 0.3 0.0016 18.2 0.2 1.6 1 0 0 1 1 1 1 HAS barrel domain Pro_isomerase PF00160.16 AEO71484.1 - 9.1e-40 136.4 0.0 1.8e-39 135.4 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HSF_DNA-bind PF00447.12 AEO71485.1 - 3.3e-28 97.9 0.2 8.3e-28 96.6 0.1 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding zf-Di19 PF05605.7 AEO71486.1 - 0.082 13.0 0.8 0.11 12.6 0.6 1.4 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Pro_isomerase PF00160.16 AEO71487.1 - 1.7e-45 154.9 0.0 2e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.17 AEO71488.1 - 3.1e-17 62.9 0.0 1.9e-15 57.1 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain tRNA_int_end_N2 PF12928.2 AEO71489.1 - 1.4e-11 43.6 0.9 5.5e-11 41.7 0.6 1.9 1 1 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 AEO71489.1 - 0.061 12.8 0.2 0.14 11.6 0.1 1.6 1 1 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain zf-ZPR1 PF03367.8 AEO71491.1 - 1.5e-104 346.0 0.3 5.4e-51 171.9 0.1 2.6 2 1 0 2 2 2 2 ZPR1 zinc-finger domain Ribosomal_60s PF00428.14 AEO71491.1 - 2.1 8.7 7.4 2.9 8.3 0.8 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein Rpr2 PF04032.11 AEO71492.1 - 4e-08 33.0 0.2 7.8e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.1 AEO71492.1 - 0.0049 16.5 4.6 0.49 10.1 0.2 2.4 2 0 0 2 2 2 2 Nudix N-terminal zf-FCS PF06467.9 AEO71492.1 - 0.074 12.7 0.6 7.9 6.2 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF866 PF05907.8 AEO71493.1 - 4.1e-45 153.1 0.1 4.6e-45 152.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF3716 PF12511.3 AEO71493.1 - 0.043 13.4 1.9 0.089 12.4 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) PHD PF00628.24 AEO71493.1 - 0.056 13.1 0.7 0.13 11.9 0.5 1.6 1 0 0 1 1 1 0 PHD-finger zinc_ribbon_4 PF13717.1 AEO71493.1 - 0.55 9.9 3.4 2.1 8.1 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AEO71493.1 - 0.56 9.8 3.4 1.9 8.1 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 AEO71493.1 - 2.1 8.2 5.3 7.6 6.4 3.7 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain PPR_2 PF13041.1 AEO71494.1 - 0.061 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 PPR repeat family GDPD PF03009.12 AEO71495.1 - 1.3e-68 231.2 0.0 2.9e-68 230.1 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 AEO71495.1 - 1.8e-33 114.7 0.9 1.7e-12 47.5 0.0 5.1 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AEO71495.1 - 7.9e-31 105.8 2.1 4.5e-11 42.9 0.1 5.7 5 0 0 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.14 AEO71495.1 - 2.4e-30 106.2 2.6 3e-16 60.0 0.4 3.7 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 AEO71495.1 - 6.3e-26 88.8 5.1 9.7e-08 31.4 0.1 7.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 AEO71495.1 - 8.5e-25 86.2 1.4 1.6e-07 31.3 0.0 5.9 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO71495.1 - 4e-14 51.3 4.6 0.00029 20.7 0.0 6.9 7 0 0 7 7 7 2 Ankyrin repeat TraD PF06412.6 AEO71495.1 - 0.046 13.3 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Conjugal transfer protein TraD WW PF00397.21 AEO71496.1 - 2.2e-07 30.5 0.3 4.4e-07 29.6 0.2 1.5 1 0 0 1 1 1 1 WW domain Pga1 PF10333.4 AEO71497.1 - 0.027 14.1 0.0 0.06 12.9 0.0 1.6 2 0 0 2 2 2 0 GPI-Mannosyltransferase II co-activator Fungal_trans_2 PF11951.3 AEO71497.1 - 0.053 12.1 0.0 0.094 11.2 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF2062 PF09835.4 AEO71497.1 - 0.059 12.9 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) ABC_membrane_2 PF06472.10 AEO71498.1 - 9.4e-101 336.6 1.5 1.5e-100 335.9 1.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 AEO71498.1 - 2.3e-17 63.5 0.0 4.5e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 AEO71498.1 - 0.01 15.3 0.0 0.15 11.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_21 PF13304.1 AEO71498.1 - 0.015 15.2 1.5 0.028 14.3 0.0 2.2 3 1 1 4 4 4 0 AAA domain AAA_16 PF13191.1 AEO71498.1 - 0.051 13.5 0.0 0.17 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 AEO71498.1 - 0.056 13.7 0.0 0.42 10.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 AEO71498.1 - 0.072 12.2 0.5 0.97 8.5 0.0 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.14 AEO71498.1 - 0.095 11.9 0.1 0.22 10.7 0.1 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain G_glu_transpept PF01019.16 AEO71500.1 - 3.7e-117 391.9 0.1 4.9e-117 391.5 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase ADH_N PF08240.7 AEO71501.1 - 2.5e-28 98.0 0.0 4.3e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO71501.1 - 8.2e-27 93.3 1.0 1.1e-26 92.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO71501.1 - 9.3e-05 23.3 0.1 0.00017 22.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 AEO71501.1 - 0.0012 18.0 0.1 0.0022 17.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1967 PF09269.6 AEO71501.1 - 0.093 12.4 0.2 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Glucokinase PF02685.11 AEO71501.1 - 0.1 11.3 2.1 0.27 9.9 1.0 1.8 1 1 1 2 2 2 0 Glucokinase Actin PF00022.14 AEO71502.1 - 1.9e-85 286.7 0.0 4.1e-85 285.5 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AEO71502.1 - 0.086 11.4 0.1 2.5 6.6 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.13 AEO71503.1 - 1e-31 109.8 4.4 6.7e-18 64.4 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.9 AEO71504.1 - 3e-83 279.2 4.2 6e-59 199.5 0.0 2.0 2 0 0 2 2 2 2 Transcription factor Tfb4 UNC45-central PF11701.3 AEO71505.1 - 2.5e-48 163.6 0.0 1.2e-47 161.4 0.0 2.2 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 AEO71505.1 - 0.00038 20.6 17.2 0.032 14.5 1.8 5.9 3 1 2 5 5 5 3 HEAT repeats Arm PF00514.18 AEO71505.1 - 0.0045 16.7 7.7 16 5.4 0.0 6.9 7 1 0 7 7 7 1 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.1 AEO71505.1 - 1.8 8.5 4.4 30 4.5 0.5 3.5 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain ERCC4 PF02732.10 AEO71506.1 - 6.9e-26 90.7 0.0 1.2e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain CAF-1_p150 PF11600.3 AEO71506.1 - 0.00047 19.6 14.2 0.001 18.4 9.8 1.6 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 AEO71506.1 - 0.076 12.8 8.2 0.15 11.9 5.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.3 AEO71506.1 - 2.9 6.5 14.3 4.4 5.9 9.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Kinesin PF00225.18 AEO71507.1 - 1.5e-92 309.9 0.0 1.5e-92 309.9 0.0 2.9 4 0 0 4 4 4 1 Kinesin motor domain AMP-binding PF00501.23 AEO71508.1 - 7.1e-93 311.2 0.2 8.6e-93 310.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO71508.1 - 9e-22 77.8 1.0 6.1e-21 75.1 0.4 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Reprolysin_5 PF13688.1 AEO71509.1 - 4.7e-60 202.8 6.3 4.7e-60 202.8 4.4 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 AEO71509.1 - 2.4e-47 161.1 0.7 5.6e-47 159.9 0.5 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 AEO71509.1 - 1.4e-46 158.6 1.6 1.4e-46 158.6 1.1 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 AEO71509.1 - 1.1e-18 67.1 29.7 1.1e-18 67.1 20.6 4.6 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.1 AEO71509.1 - 2.2e-18 66.9 0.0 2.2e-18 66.9 0.0 2.6 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.14 AEO71509.1 - 0.00013 21.7 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.14 AEO71509.1 - 0.00017 21.2 10.1 0.00017 21.2 7.0 3.6 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease DUF1191 PF06697.7 AEO71509.1 - 0.015 14.0 0.1 0.028 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) GP41 PF00517.12 AEO71509.1 - 0.016 14.7 0.6 0.039 13.5 0.4 1.5 1 0 0 1 1 1 0 Retroviral envelope protein Ribosomal_L3 PF00297.17 AEO71512.1 - 3.5e-118 393.7 9.5 4.2e-118 393.5 6.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.23 AEO71513.1 - 1.5e-56 185.8 31.0 4.8e-08 32.2 0.0 10.9 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.12 AEO71513.1 - 6.2e-51 166.2 25.8 4.6e-06 26.1 0.0 10.6 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 AEO71513.1 - 2.7e-50 167.8 49.6 1.4e-13 50.2 1.5 6.4 2 2 5 8 8 8 8 TPR repeat TPR_8 PF13181.1 AEO71513.1 - 7.8e-43 141.0 18.8 2.4e-06 26.8 0.5 10.3 8 1 2 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 AEO71513.1 - 1.6e-33 114.6 24.3 4.3e-07 30.4 0.1 7.4 4 2 5 9 9 8 8 Tetratricopeptide repeat TPR_14 PF13428.1 AEO71513.1 - 3e-33 111.2 16.3 0.00014 22.2 0.0 9.8 2 2 8 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 AEO71513.1 - 1.3e-31 108.3 23.8 1e-06 28.5 0.3 6.8 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 AEO71513.1 - 1.1e-29 100.1 19.0 0.00041 20.3 0.0 10.3 10 1 1 11 11 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 AEO71513.1 - 6.8e-25 87.2 18.1 0.00013 22.2 0.4 6.7 5 2 2 7 7 7 7 Tetratricopeptide repeat TPR_6 PF13174.1 AEO71513.1 - 1.6e-23 81.4 17.6 0.0057 17.0 0.0 10.3 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 AEO71513.1 - 9.6e-23 78.1 15.2 0.0031 17.2 0.0 9.8 8 2 1 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.1 AEO71513.1 - 2.1e-16 59.5 17.0 0.0012 18.6 0.3 7.3 1 1 6 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 AEO71513.1 - 2.5e-14 53.1 14.6 1.4e-08 34.7 1.2 4.5 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 AEO71513.1 - 9.8e-13 47.7 12.3 4e-05 22.8 0.9 4.7 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_20 PF14561.1 AEO71513.1 - 1.4e-05 25.1 3.1 0.23 11.5 0.0 5.1 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_21 PF09976.4 AEO71513.1 - 0.0012 18.8 16.4 0.11 12.4 0.0 4.7 3 3 1 4 4 4 3 Tetratricopeptide repeat MIT PF04212.13 AEO71513.1 - 0.072 12.9 17.8 1.8 8.5 1.0 5.8 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain GAS PF13851.1 AEO71513.1 - 0.091 11.9 0.3 0.47 9.6 0.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_3 PF07720.7 AEO71513.1 - 0.11 12.2 13.7 2.6 7.9 0.2 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPPII_N PF12583.3 AEO71513.1 - 0.12 12.5 0.9 7.6 6.6 0.1 2.7 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Coatomer_E PF04733.9 AEO71513.1 - 0.2 10.8 0.9 2.5 7.2 0.0 2.7 3 0 0 3 3 3 0 Coatomer epsilon subunit ChAPs PF09295.5 AEO71513.1 - 0.34 9.6 2.7 2.8 6.6 0.1 3.0 2 1 2 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.1 AEO71513.1 - 0.87 8.6 20.2 16 4.5 0.2 5.2 1 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP DUF1751 PF08551.5 AEO71514.1 - 9.4e-29 99.6 2.0 2.3e-28 98.4 1.4 1.7 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) RseC_MucC PF04246.7 AEO71514.1 - 0.27 10.8 2.5 2.5 7.6 0.1 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Rhomboid PF01694.17 AEO71514.1 - 1.4 8.9 10.2 3.3 7.7 7.1 1.6 1 0 0 1 1 1 0 Rhomboid family WD40 PF00400.27 AEO71515.1 - 8.4e-16 57.1 5.3 3.9e-05 23.3 0.0 6.6 6 0 0 6 6 6 3 WD domain, G-beta repeat LisH PF08513.6 AEO71515.1 - 7.4e-08 31.8 0.1 1.7e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 LisH Apc4_WD40 PF12894.2 AEO71515.1 - 0.0016 17.8 0.3 0.013 14.9 0.0 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 AEO71515.1 - 0.052 11.3 0.0 0.27 8.9 0.0 1.8 2 0 0 2 2 2 0 IKI3 family eIF2A PF08662.6 AEO71515.1 - 0.073 12.7 0.0 3.2 7.4 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A CDC45 PF02724.9 AEO71515.1 - 0.21 9.5 0.1 0.29 9.1 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4632 PF15451.1 AEO71515.1 - 0.32 10.9 2.7 0.42 10.5 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) Trypan_PARP PF05887.6 AEO71515.1 - 1.1 9.0 10.2 2.8 7.7 7.1 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MFS_1 PF07690.11 AEO71516.1 - 4.5e-34 117.7 49.9 4.5e-34 117.7 34.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO71516.1 - 1.2e-09 37.3 16.4 1.2e-09 37.3 11.4 2.1 2 2 0 2 2 2 1 Sugar (and other) transporter DUF1072 PF06380.6 AEO71516.1 - 0.11 12.2 0.4 0.44 10.2 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) Sugar_tr PF00083.19 AEO71517.1 - 2.7e-108 362.4 24.9 3.1e-108 362.2 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO71517.1 - 7.7e-23 80.7 34.5 7.7e-23 80.7 23.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 AEO71517.1 - 0.13 12.0 0.1 0.13 12.0 0.0 3.2 3 0 0 3 3 3 0 MFS_1 like family PspC PF04024.7 AEO71517.1 - 6.1 6.3 10.6 2 7.9 0.1 3.4 3 0 0 3 3 3 0 PspC domain adh_short PF00106.20 AEO71518.1 - 7.1e-28 97.6 1.6 1.3e-27 96.7 1.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO71518.1 - 6.5e-14 52.2 0.0 9.1e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO71518.1 - 6.1e-11 42.3 3.2 1.6e-09 37.7 2.3 2.7 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.1 AEO71518.1 - 0.019 15.0 0.4 0.24 11.3 0.1 2.1 2 0 0 2 2 2 0 NADH(P)-binding GHMP_kinases_N PF00288.21 AEO71518.1 - 0.058 13.4 0.0 0.15 12.1 0.0 1.8 1 1 0 1 1 1 0 GHMP kinases N terminal domain HI0933_like PF03486.9 AEO71518.1 - 0.092 11.1 0.2 0.13 10.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein adh_short PF00106.20 AEO71519.1 - 3.7e-10 39.9 0.0 6.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO71519.1 - 0.0015 18.1 0.0 0.0041 16.7 0.0 1.7 2 0 0 2 2 2 1 KR domain Beta-lactamase PF00144.19 AEO71520.1 - 5.5e-42 143.9 0.1 7.5e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 AEO71520.1 - 0.00048 19.4 0.1 0.00075 18.8 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Pkinase PF00069.20 AEO71521.1 - 2.4e-13 49.8 0.0 4.3e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71521.1 - 3e-08 33.0 0.0 5.7e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO71521.1 - 0.00071 18.6 0.0 0.0017 17.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like WD40 PF00400.27 AEO71524.1 - 5.8e-32 108.4 8.1 1.6e-08 34.1 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Sof1 PF04158.9 AEO71524.1 - 1e-31 108.7 15.1 1.8e-31 108.0 10.4 1.4 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 AEO71524.1 - 4.7e-05 23.1 0.1 0.32 10.7 0.0 4.0 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region DUF3022 PF11226.3 AEO71524.1 - 0.0053 16.6 0.5 0.01 15.7 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3022) PQQ_3 PF13570.1 AEO71524.1 - 0.14 12.4 1.0 12 6.2 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain AMP-binding PF00501.23 AEO71525.1 - 3e-09 35.7 0.0 3.2e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 AEO71526.1 - 1.1e-33 116.2 0.0 4.4e-33 114.2 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 AEO71526.1 - 4.4e-09 36.1 0.0 7.6e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 AEO71526.1 - 4.7e-09 36.3 0.0 1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 AEO71526.1 - 8.9e-06 25.7 3.5 4e-05 23.5 2.4 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO71526.1 - 5 6.7 9.7 0.54 9.9 1.5 3.0 3 1 0 3 3 3 0 KR domain PCI PF01399.22 AEO71527.1 - 2.5e-20 72.7 0.6 8.4e-20 71.0 0.1 2.2 3 0 0 3 3 3 1 PCI domain TPR_8 PF13181.1 AEO71527.1 - 1.2e-06 27.8 5.2 8.4 6.4 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 AEO71527.1 - 5.1e-06 25.8 6.5 0.56 10.1 0.4 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO71527.1 - 0.00049 20.6 15.4 1.8 9.3 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat DDRGK PF09756.4 AEO71527.1 - 0.0006 19.2 0.2 0.0006 19.2 0.1 1.7 2 0 0 2 2 2 1 DDRGK domain TPR_1 PF00515.23 AEO71527.1 - 0.0026 17.2 5.1 2.7 7.7 0.2 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 AEO71527.1 - 0.014 15.2 8.8 24 5.1 0.0 5.9 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 AEO71527.1 - 0.04 14.3 2.4 0.94 10.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 AEO71527.1 - 0.05 13.5 0.3 0.05 13.5 0.2 5.4 3 2 3 7 7 7 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 AEO71527.1 - 0.084 12.6 0.8 0.19 11.5 0.6 1.6 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Sds3 PF08598.6 AEO71529.1 - 2.9e-53 180.4 1.9 3.8e-53 180.0 1.3 1.3 1 0 0 1 1 1 1 Sds3-like Amidinotransf PF02274.12 AEO71529.1 - 0.0052 15.9 0.1 0.01 14.9 0.0 1.5 2 0 0 2 2 2 1 Amidinotransferase LSM PF01423.17 AEO71530.1 - 1.3e-13 50.2 0.0 2.3e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 LSM domain Glyco_hyd_65N_2 PF14498.1 AEO71531.1 - 0.044 13.4 0.0 0.089 12.4 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain PBD PF00786.23 AEO71531.1 - 0.14 12.5 0.5 0.42 11.0 0.4 1.8 1 0 0 1 1 1 0 P21-Rho-binding domain Mob1_phocein PF03637.12 AEO71532.1 - 2.6e-70 235.6 0.0 3.2e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.13 AEO71533.1 - 6.2e-40 136.8 0.3 7.7e-40 136.5 0.2 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Glyco_hydro_63 PF03200.11 AEO71534.1 - 3.9e-08 31.6 1.9 1.5e-05 23.0 0.1 3.1 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase PP2C PF00481.16 AEO71535.1 - 1.1e-41 142.9 0.0 1.8e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 AEO71535.1 - 0.00096 18.6 0.2 0.0031 16.9 0.1 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 AEO71535.1 - 0.0014 18.4 0.0 0.14 11.8 0.0 2.9 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) Molybdopterin PF00384.17 AEO71537.1 - 2.9e-76 256.9 0.0 1.3e-74 251.5 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 AEO71537.1 - 1.6e-19 69.4 0.2 4.7e-19 67.9 0.1 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 AEO71537.1 - 5.1e-19 67.2 0.1 1.5e-18 65.7 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 AEO71537.1 - 5.5e-15 55.2 0.0 1.4e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 AEO71537.1 - 3e-09 36.4 0.4 3e-09 36.4 0.3 2.6 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 AEO71537.1 - 0.00046 19.9 0.0 0.02 14.6 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Dabb PF07876.7 AEO71540.1 - 1.2e-25 89.8 0.0 1.3e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ACBP PF00887.14 AEO71541.1 - 5.9e-31 105.9 0.0 1.2e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Ribonuclease_3 PF00636.21 AEO71542.1 - 2.6e-16 60.1 0.0 5.5e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 AEO71542.1 - 3.5e-13 49.6 0.0 7.3e-13 48.5 0.0 1.5 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.20 AEO71542.1 - 0.0042 17.6 0.0 0.023 15.2 0.0 2.3 2 1 0 2 2 2 1 Double-stranded RNA binding motif MRP-S33 PF08293.6 AEO71543.1 - 1.1e-23 83.0 0.0 1.3e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PUF PF00806.14 AEO71544.1 - 1e-38 128.6 0.4 3.5e-06 26.1 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat ATG16 PF08614.6 AEO71544.1 - 0.028 14.2 4.1 0.047 13.5 2.9 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4140 PF13600.1 AEO71544.1 - 0.26 11.7 1.8 0.51 10.8 1.3 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) UPF0061 PF02696.9 AEO71545.1 - 1.9e-116 389.2 0.0 1.6e-110 369.7 0.0 2.0 2 0 0 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family SHMT PF00464.14 AEO71545.1 - 0.36 9.1 0.0 0.53 8.5 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase CAP_N PF01213.14 AEO71545.1 - 1 8.6 8.8 2.4 7.3 6.1 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Aldo_ket_red PF00248.16 AEO71546.1 - 2e-45 154.7 0.0 2.5e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family XRCC4 PF06632.7 AEO71547.1 - 5.2e-06 25.5 10.5 7.6e-06 25.0 6.5 1.7 1 1 1 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.3 AEO71547.1 - 0.0011 18.8 4.6 0.0019 18.0 3.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) LUC7 PF03194.10 AEO71547.1 - 0.0025 17.4 1.0 0.0035 16.9 0.7 1.3 1 0 0 1 1 1 1 LUC7 N_terminus DUF3584 PF12128.3 AEO71547.1 - 0.015 12.6 3.2 0.019 12.3 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HAUS6_N PF14661.1 AEO71547.1 - 0.063 12.6 3.2 0.09 12.1 2.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus IncA PF04156.9 AEO71547.1 - 0.082 12.5 2.8 0.12 11.9 1.9 1.2 1 0 0 1 1 1 0 IncA protein ERM PF00769.14 AEO71547.1 - 0.1 12.1 7.3 0.14 11.6 5.1 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AAA_23 PF13476.1 AEO71547.1 - 0.12 12.7 0.7 0.15 12.3 0.5 1.2 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 AEO71547.1 - 0.13 11.9 3.8 0.19 11.3 2.6 1.2 1 0 0 1 1 1 0 Mnd1 family Atg14 PF10186.4 AEO71547.1 - 0.23 10.3 3.7 0.32 9.8 2.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3573 PF12097.3 AEO71547.1 - 0.27 9.7 0.1 0.37 9.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Viral_P18 PF04521.8 AEO71547.1 - 0.3 10.5 2.0 0.5 9.8 1.2 1.5 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein HalX PF08663.5 AEO71547.1 - 0.3 11.0 5.6 0.91 9.5 3.9 1.8 1 0 0 1 1 1 0 HalX domain Blt1 PF12754.2 AEO71549.1 - 5.1e-39 134.7 0.0 1.7e-38 132.9 0.0 1.7 1 1 0 1 1 1 1 Cell-cycle control medial ring component ubiquitin PF00240.18 AEO71549.1 - 5.8e-05 22.4 0.0 0.0001 21.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Cofilin_ADF PF00241.15 AEO71550.1 - 6.5e-37 126.2 0.3 7.9e-37 125.9 0.2 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cys_Met_Meta_PP PF01053.15 AEO71550.1 - 0.047 11.9 0.0 0.066 11.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Cpn60_TCP1 PF00118.19 AEO71551.1 - 3.8e-119 398.4 9.0 4.4e-119 398.2 6.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pol_alpha_B_N PF08418.5 AEO71552.1 - 0.0052 16.3 2.6 0.0086 15.6 1.8 1.4 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal IER PF05760.7 AEO71552.1 - 0.34 10.7 5.9 0.62 9.9 4.1 1.4 1 0 0 1 1 1 0 Immediate early response protein (IER) Macoilin PF09726.4 AEO71552.1 - 0.9 7.7 6.0 1.2 7.3 4.2 1.0 1 0 0 1 1 1 0 Transmembrane protein Med3 PF11593.3 AEO71553.1 - 2.5 7.2 13.0 3.3 6.8 9.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RestrictionMunI PF11407.3 AEO71558.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II restriction enzyme MunI Herpes_capsid PF06112.6 AEO71558.1 - 8.5 6.4 9.7 2.9 7.9 4.6 1.7 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein p47_phox_C PF08944.6 AEO71560.1 - 3.5 7.9 13.0 2.6 8.2 7.6 1.9 1 1 1 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain TIP49 PF06068.8 AEO71561.1 - 8.2e-175 581.2 3.4 9.6e-175 581.0 2.4 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 AEO71561.1 - 1.6e-08 33.9 0.7 1.3e-05 24.3 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 AEO71561.1 - 1.9e-08 34.5 0.3 1.9e-05 24.8 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 AEO71561.1 - 8e-07 28.1 0.6 1.3e-06 27.4 0.4 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 AEO71561.1 - 6.7e-05 22.9 0.0 0.00067 19.6 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AEO71561.1 - 0.00026 21.1 0.0 0.39 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 AEO71561.1 - 0.0024 17.7 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 AEO71561.1 - 0.0024 17.3 0.1 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 AEO71561.1 - 0.0024 17.0 1.1 0.039 13.1 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 AEO71561.1 - 0.0044 16.5 0.1 1.4 8.3 0.1 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.9 AEO71561.1 - 0.011 15.4 0.2 1.6 8.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 AEO71561.1 - 0.013 15.2 0.1 0.037 13.7 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 AEO71561.1 - 0.026 14.5 0.1 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.1 AEO71561.1 - 0.051 12.2 0.2 0.14 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 AEO71561.1 - 0.064 12.8 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 AEO71561.1 - 0.086 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 GYF PF02213.11 AEO71562.1 - 4.2e-12 45.4 0.3 7.7e-12 44.6 0.2 1.5 1 0 0 1 1 1 1 GYF domain DUF2407_C PF13373.1 AEO71562.1 - 1.1 9.1 3.6 7.2 6.5 0.4 2.6 2 0 0 2 2 2 0 DUF2407 C-terminal domain Gluconate_2-dh3 PF13618.1 AEO71562.1 - 3.7 7.7 8.6 42 4.3 6.0 2.5 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 UFD1 PF03152.9 AEO71563.1 - 2.3e-61 205.9 0.0 2.9e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF3166 PF11365.3 AEO71564.1 - 0.098 13.1 0.4 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) VEFS-Box PF09733.4 AEO71565.1 - 3.2e-07 30.1 0.2 6.7e-07 29.0 0.2 1.5 1 0 0 1 1 1 1 VEFS-Box of polycomb protein PHD PF00628.24 AEO71565.1 - 0.017 14.7 12.1 0.015 14.9 7.0 1.9 2 0 0 2 2 2 0 PHD-finger LEA_5 PF00477.12 AEO71565.1 - 0.066 13.4 1.3 0.15 12.3 0.9 1.6 1 0 0 1 1 1 0 Small hydrophilic plant seed protein DUF2204 PF09970.4 AEO71566.1 - 0.0003 20.2 0.0 0.00049 19.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) TPR_14 PF13428.1 AEO71566.1 - 0.04 14.5 0.1 6.3 7.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ISK_Channel PF02060.10 AEO71566.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Slow voltage-gated potassium channel TauD PF02668.11 AEO71567.1 - 0.056 13.0 0.0 0.064 12.9 0.0 1.1 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family Metallophos PF00149.23 AEO71568.1 - 5.6e-08 32.4 3.3 3.8e-07 29.6 2.3 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AEO71568.1 - 3.5e-07 30.1 0.0 6.1e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF382 PF04037.8 AEO71569.1 - 4e-63 210.9 0.8 1.1e-62 209.6 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 AEO71569.1 - 1e-22 79.2 5.1 2.3e-22 78.1 3.5 1.6 1 0 0 1 1 1 1 PSP TPT PF03151.11 AEO71570.1 - 3.7e-36 124.0 1.0 3.7e-36 124.0 0.7 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 AEO71570.1 - 7.9e-08 31.5 9.5 2e-06 26.9 6.6 2.2 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 AEO71570.1 - 0.00037 20.5 31.6 0.00066 19.7 5.9 3.1 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 AEO71570.1 - 0.002 17.3 0.3 0.12 11.4 0.2 2.3 2 0 0 2 2 2 1 Nucleotide-sugar transporter Multi_Drug_Res PF00893.14 AEO71570.1 - 0.84 10.1 7.8 0.55 10.7 0.2 3.5 2 1 1 4 4 4 0 Small Multidrug Resistance protein ORC5_C PF14630.1 AEO71571.1 - 5.8e-77 258.7 0.0 7.8e-77 258.3 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 AEO71571.1 - 1.9e-13 50.8 0.1 5.7e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 AEO71571.1 - 0.051 12.9 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fungal_trans_2 PF11951.3 AEO71572.1 - 1.3e-06 27.3 0.1 2.2e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO71572.1 - 2e-06 27.5 10.1 3.5e-06 26.7 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-synt_ab PF00006.20 AEO71573.1 - 6.5e-62 208.8 0.0 9.6e-62 208.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AEO71573.1 - 4.1e-26 91.6 0.5 7.8e-26 90.7 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AEO71573.1 - 2.8e-25 88.3 0.5 2.4e-24 85.3 0.2 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.24 AEO71573.1 - 0.0065 16.6 0.0 0.35 11.0 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 AEO71573.1 - 0.0092 15.6 0.0 0.027 14.1 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase AAA_25 PF13481.1 AEO71573.1 - 0.011 15.2 0.6 0.065 12.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 AEO71573.1 - 0.016 14.3 0.1 0.027 13.5 0.1 1.4 1 0 0 1 1 1 0 KaiC MobB PF03205.9 AEO71573.1 - 0.016 14.8 0.2 1.1 9.0 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 AEO71573.1 - 0.021 14.0 0.1 0.039 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 AEO71573.1 - 0.029 14.0 0.2 0.078 12.6 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 AEO71573.1 - 0.031 14.2 0.3 0.28 11.1 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 AEO71573.1 - 0.045 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 AEO71573.1 - 0.11 11.3 0.9 0.55 9.0 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.1 AEO71573.1 - 0.13 12.4 0.0 0.5 10.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain Alpha-amylase_C PF02806.13 AEO71574.1 - 1.8e-25 88.8 0.0 4.9e-25 87.4 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 AEO71574.1 - 8.7e-19 68.0 0.1 2.5e-14 53.4 0.0 2.6 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 AEO71574.1 - 3.5e-15 55.7 0.0 9.1e-15 54.4 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Cellulase PF00150.13 AEO71574.1 - 0.068 12.3 0.0 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) hDGE_amylase PF14701.1 AEO71574.1 - 0.16 10.8 0.2 0.39 9.5 0.1 1.6 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme AAA_2 PF07724.9 AEO71575.1 - 6.4e-34 117.3 0.0 3.3e-33 115.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 AEO71575.1 - 3.2e-13 50.0 0.0 5.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 AEO71575.1 - 2.3e-08 33.8 0.0 5.5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 AEO71575.1 - 3.4e-08 33.3 0.0 6.8e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AEO71575.1 - 0.00018 21.3 0.1 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO71575.1 - 0.00024 21.9 0.0 0.00061 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain MCM PF00493.18 AEO71575.1 - 0.00025 19.9 0.0 0.00044 19.1 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family AAA_22 PF13401.1 AEO71575.1 - 0.00066 19.8 0.9 0.004 17.2 0.1 2.6 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 AEO71575.1 - 0.0016 17.9 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 AEO71575.1 - 0.0033 17.4 0.9 0.01 15.8 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 AEO71575.1 - 0.023 15.0 0.0 0.064 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 AEO71575.1 - 0.048 12.5 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.10 AEO71575.1 - 0.06 13.1 0.2 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 AEO71575.1 - 0.072 13.3 0.1 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 AEO71575.1 - 0.096 11.8 0.0 0.96 8.5 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 AEO71575.1 - 0.097 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 AEO71575.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 AEO71575.1 - 0.14 11.6 0.0 0.8 9.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DEAD PF00270.24 AEO71575.1 - 0.17 11.3 0.1 9.8 5.6 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_24 PF13479.1 AEO71575.1 - 0.17 11.4 0.1 0.33 10.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 AEO71576.1 - 1.8e-40 135.3 15.6 2.6e-11 42.9 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat DUF2844 PF11005.3 AEO71576.1 - 0.16 11.7 1.3 4.4 7.0 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2844) Transket_pyr PF02779.19 AEO71577.1 - 2e-64 216.3 0.0 4e-64 215.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 AEO71577.1 - 5.3e-56 189.5 0.0 8e-56 188.9 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TFIIH_BTF_p62_N PF08567.6 AEO71578.1 - 3.3e-27 93.9 0.0 9.2e-27 92.5 0.0 1.8 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.12 AEO71578.1 - 2.2e-25 88.1 13.3 2.9e-15 55.7 0.2 3.5 4 0 0 4 4 4 2 BSD domain AAA PF00004.24 AEO71579.1 - 1.6e-35 122.2 0.0 3.5e-35 121.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AEO71579.1 - 4.1e-06 26.8 3.5 0.0001 22.3 1.2 3.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AEO71579.1 - 9.1e-06 25.8 0.1 0.0072 16.4 0.0 3.5 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.7 AEO71579.1 - 6.3e-05 22.1 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 AEO71579.1 - 0.00017 22.3 0.1 0.00058 20.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO71579.1 - 0.0011 18.6 1.0 0.0081 15.8 0.0 2.8 3 0 0 3 3 2 1 Part of AAA domain AAA_33 PF13671.1 AEO71579.1 - 0.0012 18.7 0.0 0.0066 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 AEO71579.1 - 0.0017 17.7 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 AEO71579.1 - 0.0025 17.6 0.0 0.006 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO71579.1 - 0.0079 15.9 0.0 0.021 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 AEO71579.1 - 0.02 13.6 0.0 0.035 12.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 AEO71579.1 - 0.022 14.1 0.3 0.31 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 AEO71579.1 - 0.024 14.1 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 AEO71579.1 - 0.026 13.7 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 AEO71579.1 - 0.029 14.6 0.0 0.08 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AEO71579.1 - 0.031 14.4 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 AEO71579.1 - 0.034 14.1 0.0 0.089 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 AEO71579.1 - 0.06 12.9 0.2 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 AEO71579.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IPT PF01745.11 AEO71579.1 - 0.14 11.3 0.2 0.7 9.0 0.0 2.0 2 0 0 2 2 2 0 Isopentenyl transferase Sigma54_activat PF00158.21 AEO71579.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 AEO71579.1 - 0.22 10.7 0.2 0.62 9.2 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein Mus7 PF09462.5 AEO71580.1 - 2.5e-180 601.3 0.4 3.7e-180 600.8 0.3 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family COX4 PF02936.9 AEO71582.1 - 2.9e-54 182.6 0.1 3.3e-54 182.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV SRP19 PF01922.12 AEO71582.1 - 0.049 14.2 0.0 0.077 13.5 0.0 1.3 1 0 0 1 1 1 0 SRP19 protein DUF1104 PF06518.6 AEO71582.1 - 0.12 12.5 0.2 0.28 11.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DAO PF01266.19 AEO71583.1 - 1.3e-49 169.0 0.0 1.9e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 AEO71583.1 - 2e-07 30.4 0.1 5.9e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO71583.1 - 6.5e-07 28.5 0.0 1.2e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AEO71583.1 - 0.00013 21.9 0.1 0.00044 20.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AEO71583.1 - 0.0009 18.2 0.1 0.0042 15.9 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 AEO71583.1 - 0.0017 18.3 0.2 0.0054 16.7 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 AEO71583.1 - 0.0023 17.0 0.4 0.049 12.7 0.2 2.2 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.13 AEO71583.1 - 0.0028 17.3 0.1 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 AEO71583.1 - 0.0093 14.4 0.5 0.014 13.8 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 AEO71583.1 - 0.011 16.1 0.2 0.024 15.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO71583.1 - 0.017 14.0 0.0 0.14 11.0 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_10 PF13460.1 AEO71583.1 - 0.018 15.0 0.3 0.09 12.7 0.1 2.1 2 0 0 2 2 2 0 NADH(P)-binding GDI PF00996.13 AEO71583.1 - 0.063 11.5 0.1 0.66 8.2 0.0 2.0 2 0 0 2 2 2 0 GDP dissociation inhibitor Pyr_redox_3 PF13738.1 AEO71583.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 AEO71583.1 - 0.11 11.8 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RGS PF00615.14 AEO71585.1 - 1.1e-09 38.3 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_C48 PF02902.14 AEO71586.1 - 2.7e-17 63.1 0.0 4.7e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FKBP_N PF01346.13 AEO71586.1 - 8.3 6.4 5.6 16 5.5 3.9 1.4 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase MFS_1 PF07690.11 AEO71587.1 - 6.5e-25 87.5 59.5 6.4e-15 54.7 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Kelch_4 PF13418.1 AEO71588.1 - 3.4e-09 36.3 8.5 1e-07 31.6 0.1 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain LCM PF04072.9 AEO71588.1 - 1.7e-08 34.2 0.0 2.6e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_3 PF13415.1 AEO71588.1 - 0.00072 19.6 1.4 2.2 8.5 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 AEO71588.1 - 0.0011 19.0 1.3 0.12 12.5 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Cupin_8 PF13621.1 AEO71589.1 - 9.1e-22 77.7 0.0 1.1e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 AEO71589.1 - 1.1e-05 24.8 0.0 1.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Mito_carr PF00153.22 AEO71590.1 - 1.1e-45 153.2 10.7 1.3e-17 63.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 AEO71591.1 - 1.6e-16 59.9 33.0 1.7e-08 33.6 1.5 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Nodulin-like PF06813.8 AEO71591.1 - 4.5e-05 22.8 8.8 0.0037 16.5 0.4 3.3 3 0 0 3 3 3 3 Nodulin-like DUF2435 PF10363.4 AEO71592.1 - 2e-18 66.0 0.9 3.3e-17 62.1 0.0 3.2 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 AEO71592.1 - 2.4e-12 46.0 1.0 9.5e-12 44.1 0.7 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) PRMT5 PF05185.11 AEO71595.1 - 5e-144 480.5 0.0 1.2e-139 466.0 0.0 2.1 2 0 0 2 2 2 2 PRMT5 arginine-N-methyltransferase OB_NTP_bind PF07717.11 AEO71596.1 - 1.3e-27 95.9 0.6 5.1e-27 93.9 0.1 2.2 3 0 0 3 3 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 AEO71596.1 - 1.5e-22 79.4 0.0 3.4e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AEO71596.1 - 4e-11 42.6 0.0 1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AEO71596.1 - 1.8e-08 34.5 0.1 5.1e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 AEO71596.1 - 6.8e-08 32.1 0.9 1.7e-07 30.8 0.3 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase SRP54 PF00448.17 AEO71596.1 - 3.5e-05 23.3 0.2 0.00011 21.7 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 AEO71596.1 - 0.0014 17.5 0.0 0.0031 16.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 AEO71596.1 - 0.0017 18.2 0.0 0.35 10.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Response_reg PF00072.19 AEO71596.1 - 0.0033 17.4 0.5 0.16 11.9 0.1 3.0 3 0 0 3 3 3 1 Response regulator receiver domain Flavi_DEAD PF07652.9 AEO71596.1 - 0.0061 16.3 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA PF00004.24 AEO71596.1 - 0.01 16.0 0.2 0.15 12.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 AEO71596.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AEO71596.1 - 0.1 12.5 0.1 0.52 10.2 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 AEO71596.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Kelch_2 PF07646.10 AEO71597.1 - 0.17 11.7 0.3 0.23 11.3 0.2 1.3 1 1 0 1 1 1 0 Kelch motif DDHD PF02862.12 AEO71601.1 - 4.1e-38 131.4 0.0 1.8e-36 126.0 0.0 2.3 1 1 0 1 1 1 1 DDHD domain Abhydrolase_6 PF12697.2 AEO71601.1 - 0.0024 17.7 0.0 0.0024 17.7 0.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO71601.1 - 0.015 15.0 0.0 0.079 12.7 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO71601.1 - 0.18 11.3 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1227 PF06777.6 AEO71602.1 - 5.5e-62 207.7 0.1 1.3e-61 206.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 AEO71602.1 - 6.7e-52 175.4 0.5 1.2e-51 174.5 0.4 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 AEO71602.1 - 2.1e-44 151.4 0.1 6.7e-44 149.7 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain SNF2_N PF00176.18 AEO71602.1 - 1.9e-05 23.6 0.0 0.00015 20.7 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 AEO71602.1 - 0.00065 19.5 0.0 0.0023 17.7 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AEO71602.1 - 0.0012 18.3 0.0 0.38 10.2 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_11 PF13086.1 AEO71602.1 - 0.0012 18.4 0.0 0.004 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO71602.1 - 0.018 14.8 0.0 0.082 12.6 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 AEO71602.1 - 0.1 11.8 0.2 5.2 6.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein zf-C2H2 PF00096.21 AEO71603.1 - 2.8e-15 55.6 18.0 2.3e-05 24.4 0.9 3.8 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO71603.1 - 2.9e-11 42.8 19.5 0.00025 21.1 0.2 4.1 5 0 0 5 5 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO71603.1 - 5.7e-06 26.3 22.4 0.00051 20.2 1.2 4.4 4 1 1 5 5 5 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AEO71603.1 - 0.00022 21.2 10.7 0.035 14.2 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 AEO71603.1 - 0.0034 17.0 0.4 0.0034 17.0 0.3 2.1 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-BED PF02892.10 AEO71603.1 - 0.011 15.4 8.6 0.29 10.9 2.8 3.2 2 1 1 3 3 3 0 BED zinc finger zf-Di19 PF05605.7 AEO71603.1 - 0.39 10.8 4.1 6.7 6.9 0.1 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 AEO71603.1 - 0.49 10.5 7.5 0.69 10.0 1.7 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 AEO71603.1 - 0.88 9.5 11.0 0.071 13.0 1.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.2 AEO71603.1 - 1 9.6 7.0 48 4.3 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 AEO71603.1 - 1.1 9.6 11.6 3.8 7.9 4.7 2.9 1 1 2 3 3 3 0 TRAF-type zinc finger PRP3 PF08572.5 AEO71604.1 - 8.8e-71 237.8 8.3 1.3e-70 237.2 5.8 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 AEO71604.1 - 1.1e-38 131.7 0.1 2.7e-38 130.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF4230 PF14014.1 AEO71604.1 - 8.5 6.2 7.6 28 4.5 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4230) RNA_pol_Rpb1_5 PF04998.12 AEO71605.1 - 7.1e-88 294.4 0.0 1.6e-87 293.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 AEO71605.1 - 3.5e-64 215.7 0.3 9.6e-64 214.3 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 AEO71605.1 - 2.5e-31 109.1 1.5 1.5e-21 77.0 0.0 2.9 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 AEO71605.1 - 1e-29 103.2 0.0 2.5e-29 102.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 AEO71605.1 - 7.6e-18 64.2 0.0 4.8e-17 61.6 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 CDC45 PF02724.9 AEO71605.1 - 3.6 5.5 17.7 1.3 6.9 0.7 2.3 2 0 0 2 2 2 0 CDC45-like protein DSBA PF01323.15 AEO71606.1 - 2.2e-16 59.9 0.0 2.5e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Histone PF00125.19 AEO71607.1 - 3.6e-31 107.0 0.4 5.8e-31 106.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 AEO71607.1 - 4.1e-06 26.8 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AEO71607.1 - 0.004 17.1 0.3 0.0074 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 AEO71607.1 - 0.014 15.1 0.1 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 AEO71608.1 - 1.8e-15 56.7 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 AEO71608.1 - 0.00012 21.9 0.1 0.00017 21.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 AEO71608.1 - 0.00012 22.1 0.1 0.00017 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AEO71608.1 - 0.00033 20.6 0.1 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 AEO71608.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 AEO71608.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T GspH PF12019.3 AEO71609.1 - 0.18 11.9 1.0 0.4 10.8 0.1 1.8 2 0 0 2 2 2 0 Type II transport protein GspH Sugar_tr PF00083.19 AEO71610.1 - 1.1e-125 419.8 19.4 1.2e-125 419.6 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO71610.1 - 4.7e-19 68.3 30.8 1.7e-15 56.6 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 AEO71610.1 - 0.2 11.4 0.0 0.2 11.4 0.0 4.4 4 1 1 5 5 5 0 MFS_1 like family AA_permease PF00324.16 AEO71611.1 - 1.4e-132 442.4 42.1 1.7e-132 442.1 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO71611.1 - 2.6e-39 134.9 47.9 3.1e-39 134.7 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF445 PF04286.7 AEO71612.1 - 0.00056 19.5 3.2 0.0011 18.5 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF445) RVT_1 PF00078.22 AEO71612.1 - 0.0082 15.5 0.0 0.021 14.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EPSP_synthase PF00275.15 AEO71613.1 - 1.9e-126 421.8 0.0 3.8e-126 420.8 0.0 1.4 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 AEO71613.1 - 4.7e-99 330.5 0.0 8.6e-99 329.6 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 AEO71613.1 - 2.7e-62 210.3 0.0 4.6e-62 209.6 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 AEO71613.1 - 8.1e-38 129.7 0.0 1.3e-35 122.6 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 AEO71613.1 - 1.4e-24 85.9 0.0 3.2e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 AEO71613.1 - 1.6e-09 37.9 0.0 5.2e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 AEO71613.1 - 1.4e-08 34.3 0.0 3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 AEO71613.1 - 9.5e-05 23.2 0.0 0.00028 21.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain zf-C2H2 PF00096.21 AEO71614.1 - 1.6e-09 37.4 11.1 0.0065 16.7 0.8 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO71614.1 - 6.4e-06 26.1 18.7 0.0038 17.4 0.8 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger RasGAP PF00616.14 AEO71616.1 - 4.4e-47 160.3 0.1 1.3e-46 158.7 0.1 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 AEO71616.1 - 2.1e-09 37.4 0.0 4.8e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Uso1_p115_head PF04869.9 AEO71617.1 - 9.4e-113 376.0 0.0 2e-112 374.9 0.0 1.6 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 AEO71617.1 - 0.00046 20.1 13.4 0.00046 20.1 9.3 3.2 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Methyltransf_11 PF08241.7 AEO71619.1 - 5e-11 42.9 0.0 1.3e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO71619.1 - 9.7e-11 41.4 0.0 2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AEO71619.1 - 2.6e-10 39.9 0.0 4.7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 AEO71619.1 - 2e-09 37.4 0.1 6.3e-09 35.8 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO71619.1 - 2.6e-09 37.6 0.2 8.8e-09 35.9 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 AEO71619.1 - 5.4e-07 29.1 0.1 1e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 AEO71619.1 - 9.4e-07 28.6 0.0 2.3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO71619.1 - 2.6e-06 27.7 0.0 5.9e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO71619.1 - 0.00019 21.8 0.0 0.00051 20.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 AEO71619.1 - 0.0024 17.3 0.0 0.0051 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 AEO71619.1 - 0.013 15.4 0.0 0.03 14.3 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase CMAS PF02353.15 AEO71619.1 - 0.014 14.4 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 AEO71619.1 - 0.024 15.4 0.0 0.13 13.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 AEO71619.1 - 0.047 12.8 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TehB PF03848.9 AEO71619.1 - 0.051 12.7 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_9 PF08003.6 AEO71619.1 - 0.057 12.1 0.0 0.078 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PRMT5 PF05185.11 AEO71619.1 - 0.087 11.7 0.0 0.25 10.2 0.0 1.8 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase PCMT PF01135.14 AEO71619.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4407 PF14362.1 AEO71619.1 - 3.3 6.5 5.4 5 5.9 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OPT PF03169.10 AEO71620.1 - 2e-150 502.2 25.4 2.3e-150 502.0 17.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4212 PF13937.1 AEO71620.1 - 0.0042 17.0 0.6 0.0042 17.0 0.4 3.9 5 0 0 5 5 5 2 Domain of unknown function (DUF4212) Rav1p_C PF12234.3 AEO71621.1 - 4e-268 890.8 0.0 4.9e-268 890.5 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal LEA_2 PF03168.8 AEO71622.1 - 2.6e-08 34.1 1.1 0.00096 19.4 0.1 4.2 4 0 0 4 4 4 2 Late embryogenesis abundant protein DUF3712 PF12505.3 AEO71622.1 - 5.6e-08 32.8 0.0 3.9e-06 26.9 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Transglut_C PF00927.17 AEO71622.1 - 0.038 14.0 0.1 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain OTCace_N PF02729.16 AEO71623.1 - 3.5e-40 136.9 0.1 5e-40 136.4 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 AEO71623.1 - 2.6e-39 134.6 0.0 4.2e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ALS_ss_C PF10369.4 AEO71624.1 - 5.1e-19 67.7 0.0 6.5e-18 64.2 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 AEO71624.1 - 3.3e-13 48.8 0.1 6e-13 47.9 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 AEO71624.1 - 1.3e-09 37.7 0.0 2.2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 AEO71624.1 - 0.13 11.9 0.1 21 4.9 0.0 2.6 2 0 0 2 2 2 0 ACT domain KH_1 PF00013.24 AEO71625.1 - 3.1e-12 45.9 0.0 3.2e-08 33.0 0.0 2.6 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 AEO71625.1 - 1.4e-07 30.9 1.9 1e-05 25.0 0.0 3.1 3 0 0 3 3 3 2 KH domain DUF566 PF04484.7 AEO71625.1 - 6.2 6.2 7.6 9.3 5.6 5.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF974 PF06159.8 AEO71626.1 - 5e-82 275.1 0.0 6.2e-82 274.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DENN PF02141.16 AEO71627.1 - 6.9e-57 192.1 0.0 1.3e-56 191.2 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 AEO71627.1 - 5.8e-18 64.7 0.2 1e-17 63.9 0.2 1.4 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 AEO71627.1 - 3.9e-17 61.9 0.0 7.9e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 uDENN domain C1_1 PF00130.17 AEO71627.1 - 0.017 14.8 7.6 0.032 13.9 5.2 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SPA PF08616.5 AEO71627.1 - 0.065 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis PHD PF00628.24 AEO71627.1 - 0.19 11.4 6.7 0.45 10.2 4.6 1.7 1 0 0 1 1 1 0 PHD-finger C1_3 PF07649.7 AEO71627.1 - 3.5 7.7 5.5 6.9 6.7 3.8 1.5 1 0 0 1 1 1 0 C1-like domain PPI_Ypi1 PF07491.6 AEO71628.1 - 7.8e-08 31.8 11.7 1.2e-06 27.9 8.1 2.3 1 1 0 1 1 1 1 Protein phosphatase inhibitor Zip PF02535.17 AEO71628.1 - 0.25 10.3 8.2 0.25 10.3 5.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 AEO71628.1 - 1.1 8.5 15.5 0.13 11.6 7.8 1.6 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF726 PF05277.7 AEO71629.1 - 3.4e-101 338.5 0.2 3.4e-101 338.5 0.1 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Gly-zipper_OmpA PF13436.1 AEO71629.1 - 6.9 6.3 13.2 0.82 9.3 5.7 2.0 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Glu-tRNAGln PF02686.10 AEO71630.1 - 0.00051 19.7 0.0 0.0021 17.8 0.0 1.9 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit DUF605 PF04652.11 AEO71630.1 - 0.34 10.2 7.1 0.39 10.0 4.9 1.0 1 0 0 1 1 1 0 Vta1 like SNAP PF14938.1 AEO71631.1 - 1.4e-108 362.3 21.6 1.6e-108 362.1 15.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 AEO71631.1 - 4.7e-06 26.4 17.7 0.015 15.1 1.6 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 AEO71631.1 - 0.00012 21.7 23.4 0.19 11.7 0.4 6.8 5 2 1 6 6 6 2 Tetratricopeptide repeat DegS PF05384.6 AEO71631.1 - 0.0051 16.0 1.8 1.2 8.2 0.2 2.5 2 0 0 2 2 2 2 Sensor protein DegS TPR_7 PF13176.1 AEO71631.1 - 0.013 15.2 13.7 11 6.1 0.0 5.9 3 2 2 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 AEO71631.1 - 0.026 14.1 22.4 0.096 12.3 1.7 4.0 1 1 1 2 2 2 0 TPR repeat Thioesterase PF00975.15 AEO71631.1 - 0.069 13.3 1.2 0.093 12.9 0.2 1.7 2 0 0 2 2 2 0 Thioesterase domain TRAPPC-Trs85 PF12739.2 AEO71631.1 - 0.29 9.7 6.2 0.82 8.2 4.3 2.0 1 1 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit NUC173 PF08161.7 AEO71632.1 - 2.9e-79 265.0 0.0 2.7e-76 255.3 0.0 3.3 3 0 0 3 3 3 2 NUC173 domain HEAT PF02985.17 AEO71632.1 - 0.016 15.2 1.7 17 5.8 0.0 4.2 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.1 AEO71632.1 - 0.2 11.9 9.4 1.8 8.9 0.6 4.4 4 0 0 4 4 4 0 HEAT repeats MMS19_C PF12460.3 AEO71632.1 - 2.6 6.6 5.6 3.9 6.1 0.3 3.3 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal Aconitase PF00330.15 AEO71633.1 - 1.4e-70 238.0 0.0 4.7e-44 150.6 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AEO71633.1 - 4.2e-19 68.9 0.0 7.6e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain SR-25 PF10500.4 AEO71633.1 - 0.06 12.8 1.2 0.11 11.9 0.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 AEO71634.1 - 4.4e-52 176.8 0.0 6e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71634.1 - 4.9e-34 117.5 0.0 6.8e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO71634.1 - 1.7e-06 27.2 0.0 3.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA PF00498.21 AEO71634.1 - 3e-05 24.0 0.8 6e-05 23.0 0.5 1.5 1 0 0 1 1 1 1 FHA domain APH PF01636.18 AEO71634.1 - 0.0043 16.8 0.0 0.4 10.3 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 AEO71634.1 - 0.22 10.4 0.0 0.35 9.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Amino_oxidase PF01593.19 AEO71636.1 - 3.9e-16 59.1 0.2 3.2e-06 26.4 0.0 3.0 3 0 0 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 AEO71636.1 - 1.7e-13 50.3 0.0 4.2e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 AEO71636.1 - 1.7e-06 27.8 0.0 0.025 14.3 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 AEO71636.1 - 4.2e-06 25.8 0.1 0.0011 17.8 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AEO71636.1 - 6.4e-06 26.3 0.0 0.001 19.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO71636.1 - 0.0012 18.7 0.0 0.015 15.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO71636.1 - 0.013 14.3 0.1 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 AEO71636.1 - 0.018 13.5 0.0 0.67 8.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 AEO71636.1 - 0.039 14.3 0.1 0.58 10.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 AEO71636.1 - 0.054 13.0 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CtaG_Cox11 PF04442.9 AEO71637.1 - 6.7e-54 181.7 0.0 8.8e-54 181.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 MMR_HSR1 PF01926.18 AEO71638.1 - 7e-06 25.9 0.0 2.8e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase L51_S25_CI-B8 PF05047.11 AEO71639.1 - 2.5e-22 78.3 0.0 5.7e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Intimin_C PF07979.6 AEO71641.1 - 0.031 14.4 0.1 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Intimin C-type lectin domain Stc1 PF12898.2 AEO71642.1 - 8.6e-19 67.3 6.8 9.9e-19 67.1 4.7 1.0 1 0 0 1 1 1 1 Stc1 domain DSBA PF01323.15 AEO71643.1 - 0.00018 21.1 0.9 0.013 15.0 0.6 2.7 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Pkinase PF00069.20 AEO71644.1 - 8.9e-60 202.0 0.0 1.2e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71644.1 - 3.6e-32 111.4 0.0 6.7e-31 107.2 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 AEO71644.1 - 0.0078 15.0 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase DUF1387 PF07139.6 AEO71644.1 - 0.16 11.5 0.2 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) HSP70 PF00012.15 AEO71645.1 - 6.8e-09 34.1 0.5 6.5e-08 30.9 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein IKI3 PF04762.7 AEO71646.1 - 0 1070.4 0.0 0 1070.0 0.0 1.1 1 0 0 1 1 1 1 IKI3 family Clathrin PF00637.15 AEO71646.1 - 0.011 15.3 4.7 0.15 11.6 1.2 3.0 1 1 1 3 3 3 0 Region in Clathrin and VPS TPR_8 PF13181.1 AEO71646.1 - 0.24 11.2 0.9 1.5 8.7 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO71646.1 - 0.39 10.4 5.2 0.13 11.9 0.4 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 AEO71646.1 - 1.7 8.7 10.0 0.28 11.1 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 AEO71646.1 - 2.9 7.8 5.3 15 5.6 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Hpt PF01627.18 AEO71648.1 - 9.4e-13 47.9 0.2 3e-12 46.3 0.2 1.8 1 1 0 1 1 1 1 Hpt domain AKAP7_NLS PF10469.4 AEO71649.1 - 6.2e-13 48.9 0.0 8.2e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Lebercilin PF15619.1 AEO71650.1 - 0.0097 15.3 3.0 0.13 11.6 0.3 2.4 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Ribosomal_L9_C PF03948.9 AEO71650.1 - 0.058 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L9, C-terminal domain TMF_DNA_bd PF12329.3 AEO71650.1 - 0.19 11.5 5.0 0.84 9.4 0.6 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 AEO71650.1 - 1 9.0 4.2 2.7 7.7 0.4 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF605 PF04652.11 AEO71650.1 - 3.6 6.8 22.4 5.3 6.3 15.5 1.2 1 0 0 1 1 1 0 Vta1 like ADIP PF11559.3 AEO71650.1 - 7.5 6.4 7.8 1.2 8.9 1.3 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Peptidase_C31 PF05410.8 AEO71652.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.6 1 1 0 1 1 1 0 Porcine arterivirus-type cysteine proteinase alpha KOW PF00467.24 AEO71653.1 - 0.00044 19.8 0.7 0.001 18.7 0.5 1.7 1 0 0 1 1 1 1 KOW motif Histone_HNS PF00816.16 AEO71653.1 - 6 7.4 10.1 12 6.4 1.0 2.6 2 0 0 2 2 2 0 H-NS histone family Ras PF00071.17 AEO71654.1 - 9.5e-55 184.3 0.0 1.1e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO71654.1 - 1.1e-13 51.7 0.0 1.8e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO71654.1 - 4.7e-06 25.9 0.0 9.2e-06 25.0 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AEO71654.1 - 0.00032 19.9 0.0 0.0011 18.2 0.0 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 AEO71654.1 - 0.033 13.3 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AEO71654.1 - 0.055 12.8 0.0 0.4 10.1 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain zinc_ribbon_2 PF13240.1 AEO71655.1 - 0.00078 18.8 3.3 0.00078 18.8 2.3 1.9 2 0 0 2 2 2 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 AEO71655.1 - 0.003 16.7 6.0 0.003 16.7 4.1 2.3 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.2 AEO71655.1 - 0.013 15.3 6.8 0.033 14.0 4.7 1.6 1 1 0 1 1 1 0 Double zinc ribbon MSSP PF03940.8 AEO71655.1 - 0.16 11.3 7.6 0.27 10.6 5.2 1.4 1 0 0 1 1 1 0 Male specific sperm protein zf-NADH-PPase PF09297.6 AEO71655.1 - 0.45 10.0 4.6 16 5.1 3.2 2.4 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Lar_restr_allev PF14354.1 AEO71655.1 - 2.7 8.3 5.9 7.8 6.8 0.4 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar Auto_anti-p27 PF06677.7 AEO71655.1 - 2.8 7.7 8.4 2.1 8.1 0.5 2.8 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ADK_lid PF05191.9 AEO71655.1 - 4.1 7.1 6.1 14 5.3 0.3 2.6 2 0 0 2 2 2 0 Adenylate kinase, active site lid OrfB_Zn_ribbon PF07282.6 AEO71655.1 - 7.6 6.2 9.2 3 7.5 1.1 2.5 2 1 1 3 3 3 0 Putative transposase DNA-binding domain zf-tcix PF14952.1 AEO71655.1 - 8.4 5.8 10.3 3.4 7.0 0.8 2.5 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Aa_trans PF01490.13 AEO71656.1 - 1.5e-74 250.9 21.1 1.9e-74 250.6 14.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Asp PF00026.18 AEO71657.1 - 2.3e-67 227.4 4.6 2.9e-67 227.1 3.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO71657.1 - 2.4e-11 43.8 0.7 6.4e-11 42.4 0.5 1.8 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO71657.1 - 0.023 15.1 0.1 1 9.8 0.0 2.8 2 0 0 2 2 2 0 Aspartyl protease PPTA PF01239.17 AEO71658.1 - 2.2e-06 26.7 7.0 0.023 14.0 0.1 4.1 4 0 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat CHD5 PF04420.9 AEO71659.1 - 9.9e-63 210.6 0.3 1.5e-62 210.0 0.2 1.3 1 0 0 1 1 1 1 CHD5-like protein PV-1 PF06637.6 AEO71659.1 - 0.012 14.2 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Phlebovirus_NSM PF07246.6 AEO71659.1 - 0.12 11.5 0.4 0.17 11.0 0.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Bap31 PF05529.7 AEO71659.1 - 0.94 8.9 4.4 4.6 6.6 0.1 2.4 3 0 0 3 3 3 0 B-cell receptor-associated protein 31-like GRAB PF10375.4 AEO71661.1 - 1.6e-08 33.8 0.0 3e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Filament PF00038.16 AEO71661.1 - 0.00056 19.4 57.4 0.012 15.1 21.6 2.3 1 1 1 2 2 2 2 Intermediate filament protein CENP-F_leu_zip PF10473.4 AEO71661.1 - 0.0017 18.1 58.7 0.057 13.2 11.9 4.0 2 1 1 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 AEO71661.1 - 0.0098 15.1 9.9 0.31 10.1 2.0 2.8 1 1 1 2 2 2 2 Reovirus sigma C capsid protein MAD PF05557.8 AEO71661.1 - 3.6 5.5 56.2 1 7.3 18.9 2.8 1 1 0 2 2 2 0 Mitotic checkpoint protein Baculo_PEP_C PF04513.7 AEO71661.1 - 4.1 7.2 17.1 4.5 7.0 1.0 3.8 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 AEO71661.1 - 6.1 6.3 64.8 0.77 9.3 16.6 3.3 1 1 2 3 3 3 0 IncA protein NPV_P10 PF05531.7 AEO71661.1 - 7 6.9 18.4 6.8 7.0 0.9 4.8 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein RRM_1 PF00076.17 AEO71662.1 - 3.4e-14 52.2 0.1 8.3e-14 50.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO71662.1 - 2.3e-12 46.7 0.0 4.7e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO71662.1 - 1.5e-09 37.5 0.0 3.5e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APH PF01636.18 AEO71664.1 - 2.9e-05 23.9 1.1 6.3e-05 22.8 0.7 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Bac_rhodopsin PF01036.13 AEO71665.1 - 9.5e-28 97.0 27.1 1.2e-27 96.6 18.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein GWT1 PF06423.7 AEO71665.1 - 0.11 12.6 3.7 0.14 12.2 1.9 1.8 1 1 0 1 1 1 0 GWT1 Arm PF00514.18 AEO71666.1 - 2.5e-14 52.4 18.0 7.8e-05 22.3 0.1 9.6 11 0 0 11 11 11 4 Armadillo/beta-catenin-like repeat HEAT PF02985.17 AEO71666.1 - 0.00063 19.6 16.7 2.2 8.5 0.2 7.4 9 0 0 9 9 9 4 HEAT repeat Cyclin PF08613.6 AEO71667.1 - 5.7e-29 101.4 0.0 9.1e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AEO71667.1 - 3.1e-05 23.5 0.0 4.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain CHZ PF09649.5 AEO71669.1 - 5.1e-16 57.6 0.4 5.1e-16 57.6 0.3 2.6 3 0 0 3 3 3 1 Histone chaperone domain CHZ Apc15p PF05841.6 AEO71670.1 - 6e-22 78.7 0.1 6e-22 78.7 0.1 3.5 3 1 0 3 3 3 1 Apc15p protein Daxx PF03344.10 AEO71670.1 - 0.056 11.9 26.5 0.096 11.1 18.4 1.3 1 0 0 1 1 1 0 Daxx Family UPF0047 PF01894.12 AEO71670.1 - 1.3 8.9 3.9 0.93 9.3 1.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0047 Glu_synthase PF01645.12 AEO71671.1 - 1.4e-159 530.9 0.0 3.1e-159 529.7 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 AEO71671.1 - 2.7e-140 467.1 0.0 3.7e-140 466.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 AEO71671.1 - 7.5e-119 396.2 0.0 1.4e-118 395.3 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 AEO71671.1 - 4.6e-67 224.9 1.8 8.2e-67 224.1 1.3 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 AEO71671.1 - 1.5e-22 79.2 0.1 3.7e-22 78.0 0.1 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 AEO71671.1 - 1.3e-16 61.0 0.0 4.9e-16 59.2 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO71671.1 - 1.1e-11 45.1 0.4 2.2e-05 24.6 0.1 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO71671.1 - 6.1e-09 35.7 0.0 2.3e-08 33.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 AEO71671.1 - 1.6e-08 34.8 0.1 9.7e-06 25.9 0.0 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 AEO71671.1 - 3.8e-06 26.2 0.0 6.4e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 AEO71671.1 - 7.1e-06 25.1 0.3 6.3e-05 22.0 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AEO71671.1 - 3.8e-05 22.3 0.1 3.8e-05 22.3 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.1 AEO71671.1 - 6.4e-05 23.1 0.3 0.18 12.0 0.1 3.2 2 0 0 2 2 2 2 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 AEO71671.1 - 0.00011 21.7 0.2 0.003 17.1 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 AEO71671.1 - 0.00012 21.1 0.1 0.00045 19.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 AEO71671.1 - 0.00051 19.2 0.3 0.0031 16.6 0.1 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 AEO71671.1 - 0.00088 18.4 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_Gly3P_dh_N PF01210.18 AEO71671.1 - 0.0011 18.6 0.1 0.0032 17.2 0.0 1.8 2 0 0 2 2 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 AEO71671.1 - 0.0022 17.1 0.1 0.005 15.9 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FMO-like PF00743.14 AEO71671.1 - 0.012 13.8 0.1 1.9 6.5 0.0 2.7 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 AEO71671.1 - 0.02 15.0 0.3 12 5.9 0.0 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DJ-1_PfpI PF01965.19 AEO71671.1 - 0.028 13.8 0.5 0.63 9.4 0.0 2.4 1 1 1 2 2 2 0 DJ-1/PfpI family GIDA PF01134.17 AEO71671.1 - 0.068 12.0 1.7 0.14 10.9 0.0 2.2 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 AEO71671.1 - 0.072 12.8 0.0 0.25 11.1 0.0 2.0 1 0 0 1 1 1 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 AEO71671.1 - 0.073 12.2 0.4 0.54 9.3 0.0 2.4 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AEO71671.1 - 0.17 12.3 2.4 1.6 9.2 0.0 3.5 4 0 0 4 4 3 0 NADP oxidoreductase coenzyme F420-dependent FMN_dh PF01070.13 AEO71671.1 - 2.2 7.0 6.3 0.33 9.7 0.6 2.2 3 0 0 3 3 3 0 FMN-dependent dehydrogenase VTC PF09359.5 AEO71672.1 - 3.5e-98 328.0 1.2 6.2e-98 327.2 0.9 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 AEO71672.1 - 1.5e-16 61.0 23.6 6.1e-16 59.0 7.4 4.1 2 2 0 3 3 3 1 SPX domain DUF202 PF02656.10 AEO71672.1 - 1.8e-09 37.6 2.7 1.8e-09 37.6 1.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) BAR_2 PF10455.4 AEO71672.1 - 0.0027 16.6 2.1 0.0055 15.6 1.4 1.5 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking CorA PF01544.13 AEO71672.1 - 0.026 13.5 1.1 0.049 12.6 0.7 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Peptidase_C97 PF05903.9 AEO71673.1 - 1.1e-07 31.8 0.0 1.8e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 AEO71673.1 - 0.0048 16.8 1.2 0.059 13.3 0.8 2.4 1 1 0 1 1 1 1 Lecithin retinol acyltransferase DUF778 PF05608.7 AEO71673.1 - 0.058 13.3 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Velvet PF11754.3 AEO71674.1 - 1e-64 217.8 0.0 1.5e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 Velvet factor Ank PF00023.25 AEO71676.1 - 4.9e-17 60.8 1.4 2.5e-10 39.6 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 AEO71676.1 - 4.1e-16 59.1 0.1 7.7e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 AEO71676.1 - 1.1e-14 54.1 0.5 6.1e-12 45.3 0.2 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO71676.1 - 1.2e-12 47.9 1.1 2.3e-07 31.1 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) TIG PF01833.19 AEO71676.1 - 6.9e-11 41.9 0.0 1.4e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 IPT/TIG domain Ank_3 PF13606.1 AEO71676.1 - 3.3e-10 39.1 0.4 7.1e-06 25.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Na_H_Exchanger PF00999.16 AEO71677.1 - 2.9e-43 147.8 22.0 3.9e-43 147.4 15.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Vma12 PF11712.3 AEO71677.1 - 1.9 8.1 3.3 10 5.8 0.2 2.7 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase adh_short PF00106.20 AEO71678.1 - 1.2e-21 77.3 0.1 7e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 AEO71678.1 - 1.5e-07 31.4 0.0 6.6e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO71678.1 - 0.00011 21.9 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO71678.1 - 0.00021 20.8 0.0 0.00048 19.6 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Fe_hyd_lg_C PF02906.9 AEO71678.1 - 0.063 12.5 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain MFS_1 PF07690.11 AEO71679.1 - 1.5e-36 125.8 56.7 3.6e-36 124.6 34.6 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily dCMP_cyt_deam_1 PF00383.17 AEO71680.1 - 3.5e-10 39.4 0.2 6.2e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region 6PF2K PF01591.13 AEO71681.1 - 2.4e-66 222.9 0.0 1e-46 158.8 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 AEO71681.1 - 2.1e-26 92.9 0.0 5.8e-26 91.4 0.0 1.8 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 AEO71681.1 - 5e-07 29.6 0.0 5e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO71681.1 - 0.0094 16.7 0.1 0.069 13.9 0.0 2.4 2 2 0 2 2 2 1 AAA domain CARD PF00619.16 AEO71681.1 - 0.02 14.7 0.3 0.062 13.1 0.2 1.9 1 1 0 1 1 1 0 Caspase recruitment domain KTI12 PF08433.5 AEO71681.1 - 0.094 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 AEO71681.1 - 0.1 11.7 0.0 0.28 10.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Sigma70_r4_2 PF08281.7 AEO71681.1 - 0.14 11.6 0.3 3.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 Zn_clus PF00172.13 AEO71683.1 - 4.7e-08 32.8 9.0 8.2e-08 32.0 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO71683.1 - 0.00059 18.5 3.4 0.00095 17.8 2.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_cc PF11790.3 AEO71684.1 - 2.9e-61 206.9 1.4 4.1e-61 206.4 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF605 PF04652.11 AEO71684.1 - 0.16 11.2 5.2 0.27 10.5 3.6 1.4 1 0 0 1 1 1 0 Vta1 like zf-RING_2 PF13639.1 AEO71685.1 - 1.3e-13 50.5 5.8 2.2e-13 49.7 4.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AEO71685.1 - 2e-07 30.5 4.2 3.5e-07 29.7 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO71685.1 - 2.3e-07 30.8 1.7 4.5e-07 29.8 1.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 AEO71685.1 - 1.7e-06 27.6 2.3 2.8e-06 26.9 1.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO71685.1 - 3.8e-06 26.8 5.9 8.2e-06 25.7 4.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO71685.1 - 0.00016 21.2 1.8 0.00034 20.2 1.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AEO71685.1 - 0.0058 16.4 1.2 0.013 15.3 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 AEO71685.1 - 0.22 11.1 2.0 0.39 10.3 1.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CAP_GLY PF01302.20 AEO71687.1 - 5.8e-22 77.1 2.8 8.5e-22 76.6 2.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 AEO71687.1 - 7.9e-18 64.4 0.0 1.2e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 AEO71687.1 - 1.5e-05 24.2 0.0 3.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Myb_DNA-binding PF00249.26 AEO71688.1 - 1.6e-13 50.4 3.8 1.2e-09 38.0 0.2 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO71688.1 - 2.6e-09 37.0 3.6 9.9e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_Tnp_1 PF01527.15 AEO71688.1 - 0.034 14.1 0.3 11 6.0 0.2 3.1 3 0 0 3 3 3 0 Transposase Rabaptin PF03528.10 AEO71689.1 - 4 7.4 9.3 6.2 6.7 6.5 1.3 1 1 0 1 1 1 0 Rabaptin FNIP_N PF14636.1 AEO71689.1 - 4.5 7.7 9.5 5.6 7.4 6.6 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus SelP_N PF04592.9 AEO71689.1 - 5.4 6.3 13.4 6.2 6.1 9.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region BAF1_ABF1 PF04684.8 AEO71689.1 - 9 5.0 14.0 9.6 4.9 9.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Methyltransf_11 PF08241.7 AEO71690.1 - 4.7e-12 46.2 0.0 9.6e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO71690.1 - 2.2e-07 31.2 0.2 1.1e-06 28.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO71690.1 - 1.1e-06 29.1 0.3 2.4e-06 28.1 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO71690.1 - 1.7e-06 28.3 0.1 8.7e-06 26.0 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO71690.1 - 2.8e-06 27.1 0.0 4.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO71690.1 - 3.1e-06 26.8 0.0 0.00016 21.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO71690.1 - 1.7e-05 24.8 0.3 4.4e-05 23.4 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain GFO_IDH_MocA PF01408.17 AEO71691.1 - 1.3e-20 74.1 0.4 2.2e-20 73.3 0.3 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 AEO71691.1 - 0.00038 20.8 0.3 0.00064 20.1 0.2 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain OpuAC PF04069.7 AEO71691.1 - 0.0077 15.6 0.4 10 5.3 0.0 3.8 4 0 0 4 4 4 1 Substrate binding domain of ABC-type glycine betaine transport system Semialdhyde_dh PF01118.19 AEO71691.1 - 0.073 13.3 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Aldo_ket_red PF00248.16 AEO71692.1 - 1.3e-20 73.4 0.0 1.9e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Serglycin PF04360.7 AEO71693.1 - 0.015 15.0 3.0 0.017 14.8 2.1 1.2 1 0 0 1 1 1 0 Serglycin Gly-zipper_OmpA PF13436.1 AEO71693.1 - 1.8 8.2 9.4 2.1 8.0 6.5 1.2 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain CTD_bind PF04818.8 AEO71694.1 - 0.0012 19.0 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.14 AEO71694.1 - 0.14 11.8 0.1 0.49 10.0 0.0 1.9 2 1 0 2 2 2 0 VHS domain zf-C2H2_4 PF13894.1 AEO71694.1 - 0.43 11.0 2.4 1.4 9.4 1.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 AEO71694.1 - 0.87 9.3 4.4 0.41 10.3 1.1 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type 4F5 PF04419.9 AEO71696.1 - 5e-08 33.5 11.3 5e-08 33.5 7.8 1.9 1 1 1 2 2 2 1 4F5 protein family Histone_HNS PF00816.16 AEO71696.1 - 0.2 12.1 3.8 0.24 11.9 2.6 1.1 1 0 0 1 1 1 0 H-NS histone family SMN PF06003.7 AEO71698.1 - 1.1e-07 31.2 3.9 5.7e-05 22.3 0.2 2.3 1 1 0 2 2 2 2 Survival motor neuron protein (SMN) FGGY_C PF02782.11 AEO71699.1 - 2.5e-50 170.8 0.3 3.8e-50 170.2 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 AEO71699.1 - 3.6e-21 75.6 0.2 1.4e-12 47.4 0.0 3.1 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 AEO71699.1 - 0.0011 18.3 0.0 0.012 14.9 0.0 2.4 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family Nic96 PF04097.9 AEO71700.1 - 3.1e-216 719.2 0.0 3.9e-216 718.9 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 AEO71700.1 - 6.6e-10 39.2 102.3 2.6e-07 30.8 36.6 4.4 2 1 2 4 4 4 4 Nucleoporin FG repeat region DUF3425 PF11905.3 AEO71701.1 - 9.8e-22 77.3 0.2 2.9e-21 75.7 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) E1-E2_ATPase PF00122.15 AEO71703.1 - 3.9e-63 212.5 6.8 3.9e-63 212.5 4.7 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 AEO71703.1 - 4e-23 82.9 0.0 7.5e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AEO71703.1 - 3.9e-13 50.0 0.0 1e-12 48.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AEO71703.1 - 2.1e-10 39.9 0.0 4.9e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AEO71703.1 - 0.0012 18.5 0.1 0.0028 17.2 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO71703.1 - 0.029 14.3 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Mito_carr PF00153.22 AEO71704.1 - 8.5e-29 99.1 7.0 2.1e-12 46.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.16 AEO71705.1 - 1.3e-105 353.1 0.0 1.6e-105 352.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 AEO71705.1 - 0.0089 15.4 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 Eclosion hormone RRM_5 PF13893.1 AEO71706.1 - 2.1e-08 33.8 0.1 4.3e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO71706.1 - 2.8e-07 30.0 0.1 4.7e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO71706.1 - 7.1e-05 22.7 0.1 0.00021 21.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 AEO71706.1 - 0.0074 16.5 0.0 0.028 14.6 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase II-binding domain. WD40 PF00400.27 AEO71707.1 - 2.6e-05 23.9 11.7 0.34 10.8 0.1 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat AMP-binding PF00501.23 AEO71708.1 - 1e-78 264.6 0.0 1.2e-78 264.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MARVEL PF01284.18 AEO71710.1 - 5.7e-12 45.6 17.4 5.7e-11 42.4 12.0 1.9 1 1 0 1 1 1 1 Membrane-associating domain Cys_Met_Meta_PP PF01053.15 AEO71711.1 - 8.7e-151 501.5 0.0 1.4e-150 500.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF2012 PF09430.5 AEO71711.1 - 8.1e-21 74.1 0.0 1.5e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) DegT_DnrJ_EryC1 PF01041.12 AEO71711.1 - 2.9e-11 43.0 0.8 4.8e-11 42.2 0.5 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 AEO71711.1 - 3.3e-10 39.4 0.1 5.6e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 AEO71711.1 - 2.8e-08 32.8 0.2 6e-08 31.8 0.2 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AEO71711.1 - 4.4e-06 26.0 0.0 8.2e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 AEO71711.1 - 4.2e-05 22.0 0.2 6.1e-05 21.4 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 AEO71711.1 - 0.0038 15.9 0.1 0.0059 15.3 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein SelA PF03841.8 AEO71711.1 - 0.022 13.5 0.3 0.06 12.0 0.2 1.6 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase WW PF00397.21 AEO71712.1 - 7.7e-08 32.0 4.3 1.7e-07 30.9 3.0 1.6 1 0 0 1 1 1 1 WW domain Choline_transpo PF04515.7 AEO71713.1 - 9.1e-14 50.9 27.8 4.8e-12 45.2 13.8 2.8 3 0 0 3 3 3 2 Plasma-membrane choline transporter Ras PF00071.17 AEO71714.1 - 8.9e-48 161.7 0.0 1.3e-36 125.4 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 AEO71714.1 - 9.6e-16 58.3 0.0 1.6e-10 41.5 0.0 2.2 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 AEO71714.1 - 5.2e-09 35.5 0.0 7.7e-08 31.7 0.0 2.2 3 0 0 3 3 3 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AEO71714.1 - 9.7e-05 21.8 0.0 0.00049 19.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AEO71714.1 - 0.0012 17.9 0.0 0.0098 15.0 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AEO71714.1 - 0.0016 18.3 0.0 0.0047 16.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 AEO71714.1 - 0.022 14.8 0.0 0.086 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain NUDE_C PF04880.8 AEO71714.1 - 0.16 12.2 2.0 0.28 11.5 1.4 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region PMT PF02366.13 AEO71715.1 - 2.6e-79 266.0 16.7 2.6e-79 266.0 11.6 2.0 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 AEO71715.1 - 1.9e-37 128.6 0.2 2.6e-37 128.2 0.1 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.3 AEO71715.1 - 0.021 14.3 1.9 0.16 11.5 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Sugar_tr PF00083.19 AEO71716.1 - 2e-88 296.9 29.0 2.5e-88 296.6 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO71716.1 - 1.2e-20 73.5 62.0 4.8e-19 68.2 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavi_NS4A PF01350.12 AEO71716.1 - 0.11 12.0 1.0 8 6.0 0.1 3.2 3 0 0 3 3 3 0 Flavivirus non-structural protein NS4A SpoIIIAC PF06686.6 AEO71716.1 - 1.4 8.7 3.8 0.66 9.8 0.2 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family BCDHK_Adom3 PF10436.4 AEO71718.1 - 7.2e-70 233.7 0.0 1e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 AEO71718.1 - 8.4e-18 64.1 0.0 3.6e-17 62.0 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AEO71718.1 - 0.0077 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyridoxal_deC PF00282.14 AEO71719.1 - 8.9e-18 63.8 0.0 1.2e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 AEO71719.1 - 4.6e-07 28.9 0.0 9.4e-07 27.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 AEO71719.1 - 0.0079 15.2 0.0 0.023 13.7 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_transf_34 PF05637.7 AEO71720.1 - 1.4e-71 240.8 0.0 1.7e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 AEO71720.1 - 4.5e-05 22.8 0.0 0.23 10.7 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function, DUF273 RINGv PF12906.2 AEO71721.1 - 2.5e-09 37.0 4.0 7.7e-09 35.4 0.6 2.3 2 0 0 2 2 2 1 RING-variant domain zf-Sec23_Sec24 PF04810.10 AEO71721.1 - 0.011 15.3 0.5 5.4 6.6 0.1 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-RING_2 PF13639.1 AEO71721.1 - 0.011 15.5 1.2 0.011 15.5 0.9 2.3 3 0 0 3 3 3 0 Ring finger domain EIIC-GAT PF03611.9 AEO71721.1 - 0.063 12.0 0.2 1 8.0 0.0 2.0 2 0 0 2 2 2 0 PTS system sugar-specific permease component zf-C3HC4 PF00097.20 AEO71721.1 - 0.32 10.7 2.7 1.2 8.8 0.7 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 AEO71721.1 - 0.56 9.9 4.9 0.18 11.5 1.2 1.8 2 0 0 2 2 2 0 PHD-finger Acyl_transf_3 PF01757.17 AEO71721.1 - 1.8 7.3 10.0 8.1 5.1 6.9 1.9 1 1 0 1 1 1 0 Acyltransferase family Proteasome PF00227.21 AEO71722.1 - 7.6e-57 191.6 0.0 7.4e-33 113.4 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 AEO71722.1 - 2.1e-11 42.9 0.3 4.4e-11 41.8 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RCC1_2 PF13540.1 AEO71723.1 - 7.7e-17 60.4 13.5 2.4e-08 33.3 0.2 4.9 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 AEO71723.1 - 7.5e-13 48.4 0.1 0.008 16.3 0.0 5.3 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat CDC45 PF02724.9 AEO71723.1 - 0.15 10.0 5.1 0.24 9.4 3.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 AEO71723.1 - 0.24 9.8 11.7 0.35 9.3 8.1 1.2 1 0 0 1 1 1 0 Daxx Family UPF0515 PF15135.1 AEO71723.1 - 0.25 10.3 2.1 0.37 9.8 1.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 YqfQ PF14181.1 AEO71723.1 - 0.44 10.5 3.1 0.74 9.8 2.2 1.2 1 0 0 1 1 1 0 YqfQ-like protein CobT PF06213.7 AEO71723.1 - 1.4 8.0 12.6 2 7.4 8.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FimP PF09766.4 AEO71723.1 - 2.1 7.3 7.5 3.1 6.7 5.2 1.2 1 0 0 1 1 1 0 Fms-interacting protein Myc_N PF01056.13 AEO71723.1 - 2.7 7.0 6.6 4.8 6.2 4.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DUF912 PF06024.7 AEO71723.1 - 3.1 7.8 4.8 5.4 7.1 3.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TRAP_alpha PF03896.11 AEO71723.1 - 6.2 5.7 8.5 10 4.9 5.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 AEO71723.1 - 8.9 5.8 12.1 19 4.7 8.4 1.5 1 0 0 1 1 1 0 Nucleoplasmin Ribonuclease_3 PF00636.21 AEO71724.1 - 7.2e-33 113.4 0.0 6.9e-20 71.6 0.0 2.9 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 AEO71724.1 - 2.4e-18 66.3 0.0 1.9e-09 37.5 0.0 2.9 2 1 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 AEO71724.1 - 2.5e-16 59.2 0.0 4.8e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 AEO71724.1 - 3.8e-16 58.7 0.0 1.3e-15 57.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Rgp1 PF08737.5 AEO71726.1 - 1.5e-112 376.7 0.0 5.4e-112 374.9 0.0 2.0 1 1 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 AEO71726.1 - 0.046 13.5 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain LicD PF04991.8 AEO71727.1 - 2.3e-35 122.6 0.0 6.6e-34 117.8 0.0 2.1 1 1 0 1 1 1 1 LicD family ER_lumen_recept PF00810.13 AEO71729.1 - 3.2e-54 183.4 7.0 3.2e-54 183.4 4.9 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.9 AEO71729.1 - 0.0048 16.4 9.7 0.022 14.3 0.0 3.5 5 0 0 5 5 5 2 PQ loop repeat Rep_fac_C PF08542.6 AEO71730.1 - 2.1e-23 82.1 0.1 7.2e-23 80.3 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 AEO71730.1 - 6.5e-12 45.3 0.0 1.2e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 AEO71730.1 - 1.8e-06 28.1 0.1 4.2e-06 26.9 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO71730.1 - 8.6e-06 25.9 0.9 0.00012 22.2 0.2 2.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 AEO71730.1 - 1.3e-05 25.2 3.5 0.015 15.2 0.8 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 AEO71730.1 - 0.0013 18.6 0.1 0.0027 17.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 AEO71730.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_10 PF12846.2 AEO71730.1 - 0.019 14.4 0.2 1.4 8.3 0.0 2.4 1 1 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 AEO71730.1 - 0.029 14.0 0.1 0.078 12.6 0.1 1.8 1 1 0 1 1 1 0 Archaeal ATPase SNF2_N PF00176.18 AEO71730.1 - 0.029 13.1 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain T4SS-DNA_transf PF02534.9 AEO71730.1 - 0.031 12.8 0.1 0.12 10.9 0.0 1.8 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer DUF2861 PF11060.3 AEO71730.1 - 0.031 13.5 0.1 0.076 12.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2861) ABC_tran PF00005.22 AEO71730.1 - 0.079 13.2 0.1 0.16 12.2 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Ribosomal_L16 PF00252.13 AEO71731.1 - 1.4e-30 105.7 0.3 1.9e-30 105.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e 5-FTHF_cyc-lig PF01812.15 AEO71731.1 - 0.047 13.4 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family RFC1 PF08519.7 AEO71732.1 - 2e-57 193.2 0.0 4.1e-57 192.2 0.0 1.5 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 AEO71732.1 - 3.3e-13 49.5 0.0 8.8e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 AEO71732.1 - 3.6e-08 33.6 0.0 1.2e-07 31.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 AEO71732.1 - 4.2e-05 22.4 0.0 7e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 AEO71732.1 - 0.00012 22.9 2.7 0.00028 21.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 AEO71732.1 - 0.00026 21.1 0.0 0.002 18.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO71732.1 - 0.00044 19.9 0.1 0.0014 18.3 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_delta PF06144.8 AEO71732.1 - 0.001 18.5 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_18 PF13238.1 AEO71732.1 - 0.0045 17.2 0.1 0.0045 17.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AEO71732.1 - 0.005 16.8 0.4 0.058 13.3 0.0 2.8 1 1 1 3 3 3 1 AAA ATPase domain AAA_28 PF13521.1 AEO71732.1 - 0.0073 16.2 1.2 0.057 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 AEO71732.1 - 0.056 13.1 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 AEO71732.1 - 0.061 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 AEO71732.1 - 0.081 11.9 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 AEO71732.1 - 0.09 12.6 0.7 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain GrpE PF01025.14 AEO71733.1 - 2.4e-51 173.5 7.2 3.2e-51 173.1 5.0 1.1 1 0 0 1 1 1 1 GrpE IncA PF04156.9 AEO71733.1 - 0.059 12.9 5.1 0.075 12.6 3.6 1.3 1 0 0 1 1 1 0 IncA protein PfkB PF00294.19 AEO71733.1 - 0.077 12.1 0.1 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Peptidase_S49 PF01343.13 AEO71733.1 - 0.18 11.6 1.2 0.26 11.0 0.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 RNA_pol_A_bac PF01000.21 AEO71734.1 - 1.7e-32 111.9 0.0 2.5e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 AEO71734.1 - 5.8e-15 54.1 0.0 7.3e-15 53.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mito_carr PF00153.22 AEO71735.1 - 1e-59 198.2 0.5 2.9e-20 71.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Arginosuc_synth PF00764.14 AEO71736.1 - 5.6e-144 479.9 0.0 6.4e-144 479.7 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 AEO71736.1 - 0.01 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase QueC PF06508.8 AEO71736.1 - 0.063 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA-synt_2d PF01409.15 AEO71737.1 - 2.8e-45 154.4 0.2 1.8e-22 79.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 AEO71737.1 - 2.6e-25 88.4 0.0 5.8e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Calcipressin PF04847.7 AEO71738.1 - 2.5e-51 173.8 0.0 4.4e-51 173.0 0.0 1.4 1 0 0 1 1 1 1 Calcipressin Secretin_N PF03958.12 AEO71738.1 - 0.032 14.3 1.0 0.42 10.8 0.3 2.6 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain Neugrin PF06413.6 AEO71739.1 - 2.9e-12 46.9 0.2 2.9e-12 46.9 0.1 2.3 1 1 0 2 2 2 1 Neugrin MRP-L20 PF12824.2 AEO71739.1 - 0.0012 18.8 12.8 0.0029 17.5 8.8 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 YkuD PF03734.9 AEO71739.1 - 0.01 16.1 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain HTH_29 PF13551.1 AEO71739.1 - 0.026 14.6 0.0 0.095 12.8 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn helix Sigma70_r4 PF04545.11 AEO71739.1 - 0.097 12.0 0.0 0.28 10.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 DUF955 PF06114.8 AEO71739.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF955) GAGA_bind PF06217.7 AEO71739.1 - 0.18 11.7 10.7 0.26 11.2 7.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Hid1 PF12722.2 AEO71739.1 - 1.1 6.8 7.6 1.4 6.5 5.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.10 AEO71739.1 - 1.6 7.2 5.0 1.9 7.0 3.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Herpes_DNAp_acc PF04929.7 AEO71739.1 - 3.5 6.4 9.4 4.4 6.1 6.5 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Paramyxo_ncap PF00973.14 AEO71739.1 - 3.7 6.1 6.5 4.8 5.7 4.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1510 PF07423.6 AEO71739.1 - 8.7 5.6 16.9 16 4.7 11.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) WD40 PF00400.27 AEO71740.1 - 1.2e-17 63.0 9.0 2.4e-05 24.0 0.0 7.0 8 0 0 8 8 8 4 WD domain, G-beta repeat WLM PF08325.5 AEO71741.1 - 2.3e-49 167.7 0.0 3.5e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 AEO71741.1 - 0.00016 21.5 0.5 0.00047 20.0 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 AEO71741.1 - 0.0014 18.3 0.2 0.0021 17.7 0.1 1.4 1 0 0 1 1 1 1 SprT-like family Glyco_hydro_72 PF03198.9 AEO71742.1 - 2.4e-115 384.8 0.1 2.9e-115 384.6 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 AEO71742.1 - 0.00071 18.8 0.0 0.013 14.7 0.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Zn_clus PF00172.13 AEO71743.1 - 1.5e-06 28.0 10.2 2.4e-06 27.3 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 AEO71744.1 - 3.6e-41 140.8 0.0 1.1e-21 76.9 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family FBPase_glpX PF03320.8 AEO71744.1 - 0.091 11.3 0.0 0.21 10.1 0.0 1.5 2 0 0 2 2 2 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded ATP-grasp_2 PF08442.5 AEO71745.1 - 3.7e-08 33.0 0.0 5.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Citrate_synt PF00285.16 AEO71746.1 - 3.2e-19 68.9 0.0 1.4e-16 60.1 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 AEO71746.1 - 2.3e-18 66.4 0.0 5.9e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 AEO71746.1 - 8.8e-16 57.8 0.0 1.9e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 AEO71746.1 - 1.1e-05 25.0 0.0 0.0003 20.4 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain SBP_bac_11 PF13531.1 AEO71746.1 - 0.038 13.6 0.0 0.27 10.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein PBP_like_2 PF12849.2 AEO71746.1 - 0.13 11.6 0.2 1 8.7 0.0 2.1 1 1 0 2 2 2 0 PBP superfamily domain Ribosomal_L30 PF00327.15 AEO71747.1 - 1.3e-15 56.7 0.1 1.6e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Serglycin PF04360.7 AEO71747.1 - 0.048 13.3 0.1 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Serglycin MRG PF05712.8 AEO71748.1 - 7.1e-58 194.7 0.1 1.1e-57 194.1 0.1 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 AEO71748.1 - 7.1e-05 22.4 0.4 0.00013 21.6 0.3 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain ExoD PF06055.7 AEO71748.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Cnl2_NKP2 PF09447.5 AEO71749.1 - 4.6e-27 93.4 1.9 8.9e-27 92.5 1.3 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein APG6 PF04111.7 AEO71749.1 - 0.062 12.3 2.4 0.095 11.7 1.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 AEO71749.1 - 1.5 8.7 5.8 1.9 8.3 0.3 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FUSC PF04632.7 AEO71749.1 - 3.6 5.8 5.5 5.3 5.3 3.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ribosomal_60s PF00428.14 AEO71750.1 - 0.27 11.6 7.4 24 5.3 0.0 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein CENP-Q PF13094.1 AEO71751.1 - 2.3e-25 89.4 5.3 2.3e-25 89.4 3.7 3.0 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit HET PF06985.6 AEO71752.1 - 8.5e-23 81.0 0.0 1.2e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_31 PF13847.1 AEO71753.1 - 3.5e-07 29.9 0.0 6.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 AEO71753.1 - 2.8e-06 26.2 0.0 7.4e-05 21.6 0.0 2.7 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_18 PF12847.2 AEO71753.1 - 6.1e-05 23.5 0.0 0.00013 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO71753.1 - 0.00014 21.8 0.1 0.00037 20.5 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 AEO71753.1 - 0.00015 21.5 0.0 0.00041 20.0 0.0 1.7 1 0 0 1 1 1 1 TRAM domain PrmA PF06325.8 AEO71753.1 - 0.0012 17.9 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.11 AEO71753.1 - 0.058 12.2 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Glycos_transf_1 PF00534.15 AEO71754.1 - 1.1e-19 70.5 0.1 3.5e-18 65.5 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AEO71754.1 - 5e-08 33.1 0.1 2e-06 27.9 0.0 2.8 2 1 1 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 AEO71754.1 - 0.0016 18.2 0.1 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 60KD_IMP PF02096.15 AEO71755.1 - 7.9e-11 41.9 0.3 9.4e-11 41.7 0.2 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Syntaxin_2 PF14523.1 AEO71756.1 - 2.7e-27 94.7 0.6 2.7e-27 94.7 0.4 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 AEO71756.1 - 8.5e-16 57.3 7.8 9.7e-16 57.2 3.2 2.5 2 0 0 2 2 2 1 SNARE domain Vac_Fusion PF02346.11 AEO71756.1 - 0.0076 15.6 0.0 0.028 13.8 0.0 2.0 1 0 0 1 1 1 1 Chordopoxvirus fusion protein MMPL PF03176.10 AEO71756.1 - 0.01 14.6 0.6 0.01 14.6 0.4 2.0 2 1 0 2 2 2 1 MMPL family Gp-FAR-1 PF05823.7 AEO71756.1 - 0.028 14.3 1.6 0.036 14.0 0.1 1.7 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4407 PF14362.1 AEO71756.1 - 0.093 11.6 6.4 0.13 11.2 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Synaptobrevin PF00957.16 AEO71756.1 - 0.12 12.0 2.2 0.61 9.7 1.5 2.3 1 1 0 1 1 1 0 Synaptobrevin DUF883 PF05957.8 AEO71756.1 - 0.15 12.4 13.2 7.1 7.1 0.0 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.6 AEO71756.1 - 0.27 8.7 3.9 0.11 10.0 0.4 1.8 1 1 0 1 1 1 0 Prominin DUF3138 PF11336.3 AEO71756.1 - 0.63 8.1 3.5 0.81 7.7 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3450 PF11932.3 AEO71756.1 - 1.1 8.4 13.2 0.034 13.4 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ISG65-75 PF11727.3 AEO71756.1 - 1.5 7.7 9.6 0.37 9.7 2.9 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF1664 PF07889.7 AEO71756.1 - 2.2 8.0 6.0 7.1 6.4 0.9 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) Ndc1_Nup PF09531.5 AEO71757.1 - 1.9e-154 515.4 0.0 2.1e-154 515.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup IncA PF04156.9 AEO71757.1 - 0.071 12.6 0.1 0.3 10.6 0.0 2.0 2 0 0 2 2 2 0 IncA protein DUF2564 PF10819.3 AEO71757.1 - 0.083 13.0 0.4 0.19 11.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) DUF4129 PF13559.1 AEO71758.1 - 2.8e-05 23.9 0.7 8.2e-05 22.5 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Lsm_interact PF05391.6 AEO71758.1 - 0.013 14.8 0.1 0.051 13.0 0.1 2.0 1 0 0 1 1 1 0 Lsm interaction motif NICE-3 PF07406.6 AEO71758.1 - 0.081 12.4 0.2 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 NICE-3 protein Zip PF02535.17 AEO71759.1 - 0.028 13.4 5.2 0.17 10.8 4.5 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Rick_17kDa_Anti PF05433.10 AEO71759.1 - 0.053 13.1 0.3 0.053 13.1 0.2 3.4 3 0 0 3 3 3 0 Glycine zipper 2TM domain TAT_signal PF10518.4 AEO71759.1 - 0.2 11.7 0.2 0.2 11.7 0.2 3.6 4 1 1 5 5 5 0 TAT (twin-arginine translocation) pathway signal sequence BAF1_ABF1 PF04684.8 AEO71759.1 - 1.8 7.3 16.3 2.5 6.8 11.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Gly-zipper_OmpA PF13436.1 AEO71759.1 - 5.9 6.5 10.6 0.61 9.7 0.7 3.1 2 2 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain FAD_binding_3 PF01494.14 AEO71762.1 - 9.2e-75 251.8 0.0 1.2e-74 251.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 AEO71762.1 - 2e-43 147.9 0.0 3.3e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 AEO71762.1 - 0.00022 21.5 0.0 0.0035 17.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO71762.1 - 0.006 16.4 0.0 0.014 15.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO71762.1 - 0.013 14.6 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family XdhC_C PF13478.1 AEO71762.1 - 0.015 15.6 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_8 PF13450.1 AEO71762.1 - 0.025 14.5 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 AEO71762.1 - 0.031 13.2 0.0 0.07 12.0 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.19 AEO71762.1 - 0.054 12.3 0.0 0.28 10.0 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 AEO71762.1 - 0.055 11.9 0.0 0.088 11.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 AEO71762.1 - 0.098 12.0 0.1 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 AEO71762.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 ThiF family Fungal_trans PF04082.13 AEO71763.1 - 6.5e-24 84.1 0.0 1.9e-23 82.6 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO71763.1 - 2.8e-08 33.5 9.4 4.6e-08 32.8 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO71764.1 - 6.9e-50 169.7 0.0 4.5e-49 167.0 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain EphA2_TM PF14575.1 AEO71765.1 - 0.026 14.9 0.0 0.055 13.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4083 PF13314.1 AEO71765.1 - 0.064 13.1 0.2 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) TMEM154 PF15102.1 AEO71765.1 - 0.26 10.9 2.5 0.66 9.6 1.7 1.6 1 1 0 1 1 1 0 TMEM154 protein family IncA PF04156.9 AEO71765.1 - 1.1 8.8 3.6 0.26 10.8 0.2 1.6 2 0 0 2 2 2 0 IncA protein DUF2580 PF10824.3 AEO71766.1 - 0.071 13.4 0.5 0.9 9.9 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2580) Abhydrolase_3 PF07859.8 AEO71767.1 - 6.9e-34 117.2 0.0 1.8e-23 83.2 0.0 2.6 2 1 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 AEO71767.1 - 0.027 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) RAP1 PF07218.6 AEO71767.1 - 1.8 6.5 1.9 2.7 5.9 1.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Abhydrolase_5 PF12695.2 AEO71768.1 - 3.2e-07 30.2 0.4 7.8e-07 28.9 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 AEO71768.1 - 7.9e-06 25.5 0.4 1.6e-05 24.5 0.3 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 AEO71768.1 - 0.0072 15.9 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 AEO71768.1 - 0.032 14.1 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Fungal_trans PF04082.13 AEO71770.1 - 2.8e-27 95.2 0.1 5.2e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO71770.1 - 5.9e-08 32.4 12.7 1.2e-07 31.5 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABM PF03992.11 AEO71772.1 - 0.0041 17.1 0.1 0.012 15.6 0.0 1.8 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Pyridoxal_deC PF00282.14 AEO71774.1 - 6.3e-77 258.5 0.0 9.4e-77 257.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain ArdA PF07275.6 AEO71774.1 - 0.27 11.4 2.0 2.7 8.2 0.5 2.9 3 1 0 3 3 3 0 Antirestriction protein (ArdA) Aminotran_3 PF00202.16 AEO71775.1 - 6.2e-92 308.0 0.0 8.1e-92 307.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Chitin_bind_3 PF03067.10 AEO71776.1 - 0.046 13.9 1.4 0.43 10.8 0.0 2.5 2 1 0 2 2 2 0 Chitin binding domain LsmAD PF06741.8 AEO71777.1 - 3.4e-17 62.3 2.0 3.4e-17 62.3 1.4 2.0 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 AEO71777.1 - 3e-06 27.0 0.0 7e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain AIP3 PF03915.8 AEO71779.1 - 4.6e-163 543.0 7.5 7.2e-163 542.4 5.2 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.9 AEO71779.1 - 0.00081 18.8 2.7 0.00099 18.5 0.3 2.3 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain DUF1664 PF07889.7 AEO71779.1 - 0.14 11.9 4.1 2.5 7.9 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FliL PF03748.9 AEO71779.1 - 0.24 11.4 2.2 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL DivIC PF04977.10 AEO71779.1 - 1.3 8.5 11.1 1.8 8.1 0.3 4.5 4 1 1 5 5 5 0 Septum formation initiator Beta-lactamase PF00144.19 AEO71780.1 - 8.6e-10 38.1 0.2 1.2e-09 37.6 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase Myb_DNA-binding PF00249.26 AEO71781.1 - 1.4e-12 47.4 0.8 6.9e-05 22.8 0.0 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO71781.1 - 0.049 13.7 7.9 0.11 12.5 0.2 3.2 3 0 0 3 3 3 0 Myb-like DNA-binding domain DS PF01916.12 AEO71782.1 - 1.5e-142 474.0 0.0 1.9e-142 473.7 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase bZIP_1 PF00170.16 AEO71783.1 - 1.2e-08 34.7 11.7 1.2e-08 34.7 8.1 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 AEO71783.1 - 4.6e-08 32.7 9.7 4.6e-08 32.7 6.7 2.7 2 0 0 2 2 2 1 Basic region leucine zipper DUF4557 PF15101.1 AEO71783.1 - 0.084 12.7 19.1 0.16 11.7 13.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Suf PF05843.9 AEO71783.1 - 1.2 8.8 16.4 0.054 13.2 7.0 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Spore_coat_CotO PF14153.1 AEO71783.1 - 3.4 7.0 24.2 0.097 12.1 12.3 1.6 2 0 0 2 2 2 0 Spore coat protein CotO Ycf54 PF10674.4 AEO71785.1 - 0.12 12.5 0.1 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) zf-C2H2_4 PF13894.1 AEO71786.1 - 0.27 11.6 1.0 0.69 10.3 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3325 PF11804.3 AEO71786.1 - 0.27 11.1 3.9 0.72 9.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) SDA1 PF05285.7 AEO71787.1 - 5.6e-88 295.3 35.7 5.6e-88 295.3 24.7 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 AEO71787.1 - 5.4e-21 74.6 0.1 1.6e-20 73.1 0.0 1.9 1 0 0 1 1 1 1 NUC130/3NT domain Ank_2 PF12796.2 AEO71790.1 - 2.4e-08 34.1 0.8 0.00029 21.1 0.0 3.7 2 2 2 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 AEO71790.1 - 6.6e-08 31.9 2.2 3.8e-05 23.2 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 AEO71790.1 - 1e-07 31.9 4.2 0.0023 18.1 0.3 4.5 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO71790.1 - 7e-05 22.6 3.7 0.0052 16.8 0.0 3.9 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.1 AEO71790.1 - 0.0027 18.1 0.2 6.2 7.4 0.0 4.0 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Glyco_transf_90 PF05686.7 AEO71791.1 - 2.5e-12 46.2 0.0 8.3e-10 37.9 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 90 Mt_ATP-synt_D PF05873.7 AEO71791.1 - 0.12 12.0 0.1 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) HMGL-like PF00682.14 AEO71796.1 - 2.3e-40 138.7 0.5 4.8e-39 134.4 0.3 2.1 1 1 0 1 1 1 1 HMGL-like Tyrosinase PF00264.15 AEO71797.1 - 3.5e-28 99.3 1.2 5.2e-28 98.7 0.9 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Cytadhesin_P30 PF07271.6 AEO71797.1 - 0.32 10.2 2.5 0.48 9.6 1.7 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 DOCK-C2 PF14429.1 AEO71800.1 - 1.3e-25 90.1 0.0 2.1e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 AEO71800.1 - 8e-10 38.2 0.0 2e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 AEO71800.1 - 3.2e-05 23.2 0.0 6.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AEO71800.1 - 0.00013 21.4 0.0 0.001 18.5 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain Glyco_trans_2_3 PF13632.1 AEO71801.1 - 0.096 12.3 0.2 0.096 12.3 0.1 2.1 3 1 0 3 3 3 0 Glycosyl transferase family group 2 HSBP1 PF06825.7 AEO71802.1 - 0.0033 16.9 0.1 0.0077 15.7 0.1 1.6 1 0 0 1 1 1 1 Heat shock factor binding protein 1 FTA4 PF13093.1 AEO71802.1 - 0.031 13.7 0.2 0.058 12.8 0.1 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 AAA_32 PF13654.1 AEO71802.1 - 0.054 12.1 0.0 0.084 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain KfrA_N PF11740.3 AEO71802.1 - 0.3 11.5 2.0 1.1 9.7 0.1 2.5 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term DUF1547 PF07577.6 AEO71802.1 - 2.2 7.9 4.8 2.7 7.7 0.8 2.7 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1547) P5CR_dimer PF14748.1 AEO71803.1 - 0.017 15.0 0.0 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation CN_hydrolase PF00795.17 AEO71805.1 - 1.6e-19 69.9 0.0 2.8e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF2733 PF10813.3 AEO71805.1 - 0.06 12.9 0.2 2.1 7.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) HATPase_c_3 PF13589.1 AEO71807.1 - 3.8e-16 58.9 0.0 6.1e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 AEO71807.1 - 1.1e-08 34.7 0.1 1.5e-07 31.1 0.1 2.6 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 AEO71807.1 - 0.00099 18.8 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Clathrin PF00637.15 AEO71808.1 - 1.5e-24 86.1 1.2 8.5e-24 83.7 1.1 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.3 AEO71808.1 - 1.7e-21 75.7 0.2 7.7e-21 73.6 0.2 2.1 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 AEO71808.1 - 1.1e-05 25.0 0.1 3.8e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 AEO71808.1 - 0.00097 18.8 0.1 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.1 AEO71808.1 - 0.0017 17.9 0.2 0.025 14.2 0.0 2.7 2 0 0 2 2 2 1 TPR repeat zf-C3HC4 PF00097.20 AEO71808.1 - 0.01 15.4 0.4 0.01 15.4 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.1 AEO71808.1 - 0.016 15.7 1.7 17 6.4 0.0 4.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 AEO71808.1 - 0.03 14.6 4.3 3.3 8.0 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 AEO71808.1 - 0.051 13.6 7.0 0.32 11.0 2.9 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_8 PF13181.1 AEO71808.1 - 0.22 11.3 5.9 0.24 11.2 0.3 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 AEO71808.1 - 0.34 10.9 0.1 0.34 10.9 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 AEO71808.1 - 0.51 10.3 9.7 0.51 10.3 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat BPL_LplA_LipB PF03099.14 AEO71809.1 - 7.1e-11 42.2 0.0 3.2e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.16 AEO71810.1 - 2.3e-126 420.9 0.0 5.9e-126 419.6 0.0 1.6 1 1 0 1 1 1 1 Chorismate synthase Tetraspannin PF00335.15 AEO71811.1 - 0.00027 20.2 0.5 0.0022 17.3 0.0 2.0 2 0 0 2 2 2 1 Tetraspanin family SSP160 PF06933.6 AEO71811.1 - 0.043 11.8 4.0 0.062 11.2 2.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Phage_lysozyme PF00959.14 AEO71812.1 - 1.1e-14 54.6 0.0 5e-14 52.5 0.0 1.9 2 0 0 2 2 2 1 Phage lysozyme SH3_3 PF08239.6 AEO71812.1 - 0.00014 21.9 1.9 0.00085 19.4 0.3 2.4 2 0 0 2 2 2 1 Bacterial SH3 domain Ig_2 PF13895.1 AEO71812.1 - 0.019 15.1 1.0 1.4 9.0 0.1 2.4 2 0 0 2 2 2 0 Immunoglobulin domain Endotoxin_C PF03944.9 AEO71812.1 - 0.13 12.4 0.3 0.18 11.9 0.2 1.2 1 0 0 1 1 1 0 delta endotoxin CHAP PF05257.11 AEO71813.1 - 2.2e-19 69.3 9.3 2.2e-19 69.3 6.4 1.6 2 0 0 2 2 2 1 CHAP domain SH3_3 PF08239.6 AEO71813.1 - 0.0011 19.0 1.8 0.0012 19.0 0.2 1.9 2 0 0 2 2 2 1 Bacterial SH3 domain Pkinase PF00069.20 AEO71815.1 - 6.2e-18 64.8 0.0 8.7e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71815.1 - 1.3e-08 34.2 0.0 1.8e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO71815.1 - 6.3e-08 31.9 0.0 1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AEO71815.1 - 6.8e-05 22.0 0.0 9.5e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO71815.1 - 0.00013 21.7 0.3 0.0089 15.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 AEO71815.1 - 0.0099 15.2 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.6 AEO71815.1 - 0.015 14.1 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 zf-C2H2_6 PF13912.1 AEO71816.1 - 0.0055 16.5 0.3 0.054 13.4 0.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger Inhibitor_I53 PF11714.3 AEO71816.1 - 0.038 13.9 0.6 0.14 12.1 0.4 1.9 1 0 0 1 1 1 0 Thrombin inhibitor Madanin zf-C2H2_4 PF13894.1 AEO71816.1 - 0.1 12.9 11.2 1.3 9.4 0.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO71816.1 - 2.5 8.6 12.1 1.2 9.6 0.2 3.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type BTB PF00651.26 AEO71817.1 - 1.1e-06 28.5 0.1 8.3e-05 22.5 0.0 2.4 2 1 1 3 3 3 1 BTB/POZ domain RE_LlaJI PF09563.5 AEO71817.1 - 0.092 11.4 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 LlaJI restriction endonuclease adh_short PF00106.20 AEO71818.1 - 1.2e-17 64.3 3.7 1.8e-17 63.7 2.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO71818.1 - 1.6e-11 44.2 2.5 2.5e-11 43.5 1.7 1.3 1 0 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.3 AEO71819.1 - 6.9e-06 24.8 0.0 9.5e-06 24.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4446 PF14584.1 AEO71821.1 - 0.098 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2254 PF10011.4 AEO71821.1 - 0.12 10.7 0.0 0.13 10.7 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) TMEM52 PF14979.1 AEO71821.1 - 0.15 11.9 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Transmembrane 52 MFS_1 PF07690.11 AEO71822.1 - 7e-27 94.0 63.6 2.1e-21 76.0 28.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO71822.1 - 2.7e-14 52.6 27.3 3.9e-14 52.0 18.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter LacAB_rpiB PF02502.13 AEO71822.1 - 0.097 12.3 0.6 0.18 11.4 0.4 1.4 1 0 0 1 1 1 0 Ribose/Galactose Isomerase CBM_1 PF00734.13 AEO71823.1 - 1.2e-13 50.4 12.4 1.2e-13 50.4 8.6 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF3595 PF12166.3 AEO71823.1 - 0.13 11.0 0.3 0.18 10.6 0.1 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3595) AcetylCoA_hydro PF02550.10 AEO71824.1 - 7.4e-50 169.4 0.0 1.1e-49 168.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 AEO71824.1 - 1.5e-37 128.6 0.0 2.2e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain MFS_1 PF07690.11 AEO71825.1 - 9.7e-14 50.8 32.0 9.7e-14 50.8 22.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 AEO71825.1 - 7.5e-12 45.0 4.8 7.5e-12 45.0 3.3 3.0 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 Glyco_hydro_2_N PF02837.13 AEO71826.1 - 6.9e-34 116.8 0.1 2.8e-33 114.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 AEO71826.1 - 1.5e-29 102.8 0.0 2.9e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 AEO71826.1 - 3.8e-15 56.2 1.4 5.8e-15 55.7 0.2 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 DBB PF14545.1 AEO71826.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Dof, BCAP, and BANK (DBB) motif, Pkinase PF00069.20 AEO71827.1 - 8.1e-06 25.1 0.0 9e-05 21.7 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Zn_clus PF00172.13 AEO71828.1 - 0.0083 16.0 3.3 0.02 14.7 2.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 AEO71829.1 - 6.5e-27 94.8 0.0 8.4e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Amidase PF01425.16 AEO71830.1 - 7.7e-70 235.9 0.0 9.3e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Amidase RasGEF PF00617.14 AEO71833.1 - 4.6e-54 183.0 0.0 1e-53 181.9 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 AEO71833.1 - 1.1e-15 57.6 0.0 2.6e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 AEO71833.1 - 2e-06 27.2 0.0 4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AEO71833.1 - 3.8e-05 22.9 0.0 7.8e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AEO71833.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain MFS_1 PF07690.11 AEO71834.1 - 1.1e-28 100.0 23.1 1.1e-28 100.0 16.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO71834.1 - 4.3e-08 32.1 11.4 8.2e-08 31.2 3.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DNA_binding_1 PF01035.15 AEO71836.1 - 1.7e-19 69.2 0.1 2e-19 69.0 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain His_Phos_1 PF00300.17 AEO71837.1 - 3.3e-21 76.0 0.0 2.6e-20 73.1 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 AEO71837.1 - 5.8e-05 22.5 0.2 0.00011 21.6 0.1 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PAS_4 PF08448.5 AEO71837.1 - 0.069 13.1 1.6 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 PAS fold Asp PF00026.18 AEO71839.1 - 2.3e-07 30.3 0.0 7.8e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.5 AEO71839.1 - 0.35 10.2 4.6 0.94 8.8 3.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Nitrate_red_gam PF02665.9 AEO71839.1 - 0.4 9.9 1.2 0.77 9.0 0.8 1.4 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Bromodomain PF00439.20 AEO71841.1 - 9.5e-13 47.8 0.0 2.3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Aldo_ket_red PF00248.16 AEO71842.1 - 6.1e-09 35.1 0.0 6.8e-09 34.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Filament PF00038.16 AEO71844.1 - 0.00075 19.0 0.9 0.00075 19.0 0.6 1.9 2 0 0 2 2 2 1 Intermediate filament protein HCMV_UL139 PF12507.3 AEO71844.1 - 0.012 15.7 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein DUF1183 PF06682.7 AEO71844.1 - 0.014 15.0 4.5 0.019 14.5 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) SPX PF03105.14 AEO71844.1 - 0.022 14.5 4.5 0.026 14.2 3.1 1.0 1 0 0 1 1 1 0 SPX domain Cob_adeno_trans PF01923.13 AEO71844.1 - 0.031 14.0 0.2 0.031 14.0 0.2 1.4 2 0 0 2 2 2 0 Cobalamin adenosyltransferase PspA_IM30 PF04012.7 AEO71844.1 - 0.041 13.2 1.0 0.041 13.2 0.7 2.1 2 0 0 2 2 2 0 PspA/IM30 family Striatin PF08232.7 AEO71844.1 - 0.057 13.7 7.0 0.086 13.1 4.9 1.2 1 0 0 1 1 1 0 Striatin family SlyX PF04102.7 AEO71844.1 - 0.058 13.7 2.8 0.058 13.7 2.0 3.2 2 1 1 3 3 3 0 SlyX vMSA PF00695.14 AEO71844.1 - 0.095 11.8 8.0 0.11 11.7 5.5 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF2360 PF10152.4 AEO71844.1 - 0.3 11.3 9.2 0.43 10.8 6.4 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) AAA_23 PF13476.1 AEO71844.1 - 0.42 10.8 4.5 0.57 10.4 3.1 1.1 1 0 0 1 1 1 0 AAA domain Suf PF05843.9 AEO71844.1 - 0.51 10.0 10.0 0.63 9.7 6.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 AEO71844.1 - 0.74 9.1 17.3 0.85 8.9 12.0 1.1 1 0 0 1 1 1 0 Vta1 like DUF16 PF01519.11 AEO71844.1 - 0.78 9.9 8.8 0.16 12.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 Allexi_40kDa PF05549.6 AEO71844.1 - 1 8.6 6.0 2.3 7.4 4.1 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein ADIP PF11559.3 AEO71844.1 - 1.3 8.9 12.3 0.062 13.1 0.5 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 AEO71844.1 - 1.6 8.5 12.2 0.18 11.6 1.4 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Rtf2 PF04641.7 AEO71844.1 - 1.8 7.6 7.9 2.3 7.3 5.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Spc24 PF08286.6 AEO71844.1 - 1.9 8.1 8.0 0.24 11.1 0.2 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF2076 PF09849.4 AEO71844.1 - 2 8.3 17.7 3 7.8 12.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Uds1 PF15456.1 AEO71844.1 - 2.3 8.2 8.8 3.6 7.5 1.1 1.7 1 1 1 2 2 2 0 Up-regulated During Septation PAT1 PF09770.4 AEO71844.1 - 2.6 6.1 20.3 2.8 6.0 14.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 AEO71844.1 - 3.3 5.2 7.5 3.7 5.1 5.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Lin-8 PF03353.10 AEO71844.1 - 4.1 6.5 11.2 4.9 6.3 7.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Atg14 PF10186.4 AEO71844.1 - 7 5.4 9.6 0.26 10.1 0.5 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ERF PF04404.7 AEO71844.1 - 7.6 6.0 10.6 3.1 7.2 5.6 1.6 2 0 0 2 2 2 0 ERF superfamily Spc7 PF08317.6 AEO71844.1 - 8.4 4.9 9.9 0.079 11.6 1.3 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein MerR-DNA-bind PF09278.6 AEO71844.1 - 8.5 6.8 11.0 0.35 11.3 1.3 2.3 2 0 0 2 2 2 0 MerR, DNA binding Asp PF00026.18 AEO71845.1 - 4.2e-47 160.9 0.0 8.2e-47 159.9 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 AEO71845.1 - 2.6e-05 23.8 0.0 5.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 AEO71845.1 - 4.8e-05 23.3 0.1 0.00014 21.8 0.1 1.8 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal HSP70 PF00012.15 AEO71846.1 - 1.5e-54 185.0 37.3 1.4e-50 171.8 0.2 4.2 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 AEO71846.1 - 0.00095 17.8 0.1 0.014 14.0 0.0 2.6 3 0 0 3 3 3 1 MreB/Mbl protein DUF348 PF03990.9 AEO71846.1 - 0.035 13.6 1.3 2.3 7.8 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF348) PIG-L PF02585.12 AEO71846.1 - 0.46 10.9 0.0 0.46 10.9 0.0 2.6 3 0 0 3 3 3 0 GlcNAc-PI de-N-acetylase Pex14_N PF04695.8 AEO71846.1 - 6.3 6.8 37.0 5.6 7.0 13.9 4.1 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DEAD PF00270.24 AEO71847.1 - 1.3e-31 109.3 0.0 5.3e-15 55.3 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO71847.1 - 2.9e-21 75.1 0.1 6.1e-21 74.0 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO71847.1 - 1.7e-06 27.9 0.0 5e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 AEO71847.1 - 0.023 14.4 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain PIGA PF08288.7 AEO71848.1 - 6.7e-47 157.7 4.1 1.4e-46 156.8 1.1 2.5 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 AEO71848.1 - 9.2e-29 100.0 0.0 1.4e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 AEO71848.1 - 1e-18 67.6 1.2 2e-18 66.7 0.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 AEO71848.1 - 4.5e-17 62.6 0.0 8.7e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 AEO71848.1 - 6.2e-16 58.7 0.0 1e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 AEO71848.1 - 9.8e-08 31.9 0.3 1.7e-07 31.1 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 AEO71848.1 - 0.00044 20.4 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 AEO71848.1 - 0.078 12.4 0.1 0.25 10.8 0.1 1.9 1 1 0 1 1 1 0 Starch synthase catalytic domain Acetyltransf_1 PF00583.19 AEO71849.1 - 1.7e-10 40.8 0.1 7.3e-08 32.3 0.0 2.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO71849.1 - 2e-06 27.8 0.1 4.6e-05 23.5 0.1 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 AEO71849.1 - 6.3e-06 26.6 0.0 0.0037 17.8 0.0 2.3 1 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AEO71849.1 - 0.00022 21.0 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 AEO71849.1 - 0.013 15.6 0.0 0.047 13.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Sporozoite_P67 PF05642.6 AEO71849.1 - 0.089 10.6 2.4 0.11 10.3 1.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Acetyltransf_3 PF13302.1 AEO71849.1 - 0.1 12.7 0.0 0.66 10.1 0.0 2.1 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Mucin PF01456.12 AEO71849.1 - 0.38 10.5 22.9 0.68 9.7 15.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 AEO71849.1 - 8.2 4.2 20.8 11 3.8 14.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ribosomal_S7 PF00177.16 AEO71850.1 - 4.8e-41 139.7 1.0 6e-41 139.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S25 PF03297.10 AEO71851.1 - 4.8e-40 135.8 5.8 5.3e-40 135.7 4.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein RNA_pol_Rpc34 PF05158.7 AEO71851.1 - 0.0015 17.7 0.2 0.0023 17.1 0.1 1.3 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_24 PF13412.1 AEO71851.1 - 0.0033 16.7 0.1 0.0051 16.1 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 AEO71851.1 - 0.004 16.7 0.1 0.0053 16.4 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_DeoR PF08220.7 AEO71851.1 - 0.0041 16.6 0.1 0.0057 16.1 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.15 AEO71851.1 - 0.019 15.0 0.1 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.14 AEO71851.1 - 0.023 14.3 0.2 0.033 13.8 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 AEO71851.1 - 0.076 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 HTH domain HTH_IclR PF09339.5 AEO71851.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain FeoC PF09012.5 AEO71851.1 - 0.14 11.8 0.3 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator Mito_carr PF00153.22 AEO71852.1 - 1.1e-67 223.8 4.1 7.4e-24 83.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CENP-X PF09415.5 AEO71853.1 - 1.3e-27 95.4 0.3 2.3e-27 94.5 0.2 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X NYN PF01936.13 AEO71854.1 - 1.3e-07 31.9 0.0 0.00075 19.7 0.0 2.2 2 0 0 2 2 2 2 NYN domain zf-CCCH PF00642.19 AEO71854.1 - 0.0085 15.7 7.8 1.5 8.6 0.8 3.6 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF116 PF01976.12 AEO71854.1 - 0.54 9.7 4.0 0.47 9.9 1.3 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF116 zf-CCCH_2 PF14608.1 AEO71854.1 - 2 8.5 12.4 3.9 7.6 1.9 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DUF2981 PF11200.3 AEO71854.1 - 2.1 7.3 7.3 3 6.8 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Cupredoxin_1 PF13473.1 AEO71855.1 - 0.0075 16.1 0.1 0.016 15.0 0.0 1.6 1 1 0 1 1 1 1 Cupredoxin-like domain Cyt-b5 PF00173.23 AEO71856.1 - 2.4e-07 30.4 0.0 3.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Lebercilin PF15619.1 AEO71857.1 - 1.2 8.5 35.9 0.24 10.8 21.0 2.3 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease APG6 PF04111.7 AEO71858.1 - 0.002 17.2 8.2 0.0039 16.2 5.7 1.4 1 0 0 1 1 1 1 Autophagy protein Apg6 Cast PF10174.4 AEO71858.1 - 0.0047 15.0 13.2 0.0082 14.2 9.1 1.3 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Spc7 PF08317.6 AEO71858.1 - 0.014 14.1 12.6 0.03 13.0 8.7 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Herpes_UL6 PF01763.11 AEO71858.1 - 0.18 9.9 3.8 0.34 9.0 2.7 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like AAA_13 PF13166.1 AEO71858.1 - 0.27 9.6 8.9 0.5 8.7 6.1 1.3 1 0 0 1 1 1 0 AAA domain Seadorna_VP6 PF07407.6 AEO71858.1 - 0.36 9.5 1.3 0.71 8.5 0.8 1.4 1 1 0 1 1 1 0 Seadornavirus VP6 protein Reo_sigmaC PF04582.7 AEO71858.1 - 0.68 9.0 4.1 1.1 8.3 2.9 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 AEO71858.1 - 1.2 8.9 6.6 0.87 9.3 3.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF334 PF03904.8 AEO71858.1 - 3.2 7.0 8.5 7.9 5.7 5.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DivIC PF04977.10 AEO71858.1 - 7.5 6.1 13.3 5.6 6.5 2.4 3.0 1 1 2 3 3 3 0 Septum formation initiator TPR_MLP1_2 PF07926.7 AEO71858.1 - 9.2 6.0 26.1 2.9 7.6 13.5 3.1 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF812 PF05667.6 AEO71858.1 - 9.9 4.5 16.7 1.2 7.5 7.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) BTB_2 PF02214.17 AEO71859.1 - 3.9e-05 23.7 0.1 0.0055 16.8 0.0 2.6 3 0 0 3 3 3 2 BTB/POZ domain Tubulin PF00091.20 AEO71860.1 - 6e-70 235.4 0.0 8.5e-70 234.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AEO71860.1 - 1.5e-48 163.9 0.1 2.6e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 AEO71860.1 - 0.00019 20.9 0.0 0.00039 19.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain EF-hand_4 PF12763.2 AEO71861.1 - 3.4e-27 94.2 0.0 3.9e-13 49.0 0.0 3.3 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 AEO71861.1 - 5.6e-10 39.2 0.0 6.2e-07 29.4 0.2 3.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 AEO71861.1 - 2.1e-06 26.6 0.0 0.59 9.5 0.1 4.5 4 0 0 4 4 4 2 EF hand UBA PF00627.26 AEO71861.1 - 6.5e-06 25.8 0.7 2.2e-05 24.1 0.1 2.2 2 0 0 2 2 2 1 UBA/TS-N domain EF-hand_6 PF13405.1 AEO71861.1 - 7.7e-05 22.2 0.3 0.14 12.1 0.2 4.1 4 0 0 4 4 4 1 EF-hand domain Macoilin PF09726.4 AEO71861.1 - 0.00026 19.4 18.1 0.00026 19.4 12.6 3.7 3 1 0 3 3 2 1 Transmembrane protein WEMBL PF05701.6 AEO71861.1 - 0.0025 16.3 32.0 0.0054 15.2 22.2 1.4 1 0 0 1 1 1 1 Weak chloroplast movement under blue light GAS PF13851.1 AEO71861.1 - 0.051 12.7 36.3 0.65 9.1 15.6 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 AEO71861.1 - 0.057 13.2 35.1 0.08 12.8 10.2 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF960 PF06124.6 AEO71861.1 - 0.12 12.6 0.2 6.9 6.9 0.0 3.1 3 0 0 3 3 3 0 Staphylococcal protein of unknown function (DUF960) DUF1664 PF07889.7 AEO71861.1 - 0.15 11.8 15.4 0.025 14.3 4.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CALCOCO1 PF07888.6 AEO71861.1 - 0.31 9.2 23.9 0.61 8.3 16.5 1.5 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_27 PF13514.1 AEO71861.1 - 0.87 7.1 41.0 0.016 12.9 19.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 AEO71861.1 - 1.4 7.2 28.8 2.6 6.3 20.0 1.3 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 AEO71861.1 - 2 7.5 14.8 0.78 8.8 3.5 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein COG2 PF06148.6 AEO71861.1 - 3.4 7.5 16.3 0.13 12.1 2.7 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 AEO71861.1 - 4.1 5.9 33.3 2.3 6.7 6.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 AEO71861.1 - 6.1 6.6 30.4 8.7 6.0 3.2 3.7 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Filament PF00038.16 AEO71861.1 - 6.4 6.1 33.7 3.7 6.9 10.2 2.3 1 1 1 2 2 2 0 Intermediate filament protein FlaC_arch PF05377.6 AEO71861.1 - 9 6.2 18.3 2.8 7.8 0.6 4.1 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) zf-CSL PF05207.8 AEO71862.1 - 1.6e-24 85.1 1.9 2e-24 84.8 1.3 1.1 1 0 0 1 1 1 1 CSL zinc finger tRNA-synt_1 PF00133.17 AEO71863.1 - 1.9e-38 131.8 0.0 1.9e-27 95.5 0.0 3.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 AEO71863.1 - 4.9e-20 71.5 0.0 8.6e-12 44.4 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 AEO71863.1 - 1.1e-14 54.4 1.1 2.5e-14 53.2 0.3 1.9 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 AEO71863.1 - 5.1e-08 32.3 0.0 1.2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain BESS PF02944.15 AEO71864.1 - 0.12 11.9 0.2 0.32 10.5 0.1 1.7 1 0 0 1 1 1 0 BESS motif Clat_adaptor_s PF01217.15 AEO71865.1 - 5.6e-43 146.0 0.0 1e-42 145.2 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Frataxin_Cyay PF01491.11 AEO71866.1 - 1.1e-34 118.4 0.0 1.6e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Glyco_transf_15 PF01793.11 AEO71870.1 - 9e-119 396.2 0.0 1.1e-118 395.9 0.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PRESAN PF09687.5 AEO71871.1 - 0.063 13.3 0.3 0.088 12.8 0.2 1.2 1 0 0 1 1 1 0 Plasmodium RESA N-terminal DUF996 PF06195.8 AEO71871.1 - 0.12 12.3 5.6 0.16 11.9 3.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF996) WD40 PF00400.27 AEO71872.1 - 2.9e-97 315.4 48.1 1.5e-15 56.3 1.5 8.0 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 AEO71872.1 - 6.4e-18 64.1 24.8 0.005 15.0 0.4 7.0 1 1 6 7 7 7 7 Nucleoporin Nup120/160 Nbas_N PF15492.1 AEO71872.1 - 1.8e-10 40.4 19.3 0.0072 15.4 0.2 6.0 1 1 5 6 6 6 6 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 AEO71872.1 - 0.00017 20.0 0.6 2.3 6.4 0.0 3.1 1 1 0 3 3 3 3 Cytochrome D1 heme domain DUF1652 PF07865.6 AEO71872.1 - 0.00035 20.1 0.1 37 4.0 0.0 5.7 7 0 0 7 7 7 0 Protein of unknown function (DUF1652) Gp5_C PF06715.7 AEO71872.1 - 0.0028 17.4 0.6 74 3.5 0.0 5.5 6 0 0 6 6 6 0 Gp5 C-terminal repeat (3 copies) HARP PF07443.8 AEO71872.1 - 0.0084 15.4 0.6 11 5.5 0.0 4.1 4 0 0 4 4 4 1 HepA-related protein (HARP) IKI3 PF04762.7 AEO71872.1 - 7 4.3 15.4 6.8 4.3 0.1 4.3 2 2 1 5 5 5 0 IKI3 family zf-C2H2_4 PF13894.1 AEO71873.1 - 0.13 12.6 6.2 5 7.7 0.0 4.6 5 0 0 5 5 5 0 C2H2-type zinc finger Sulfotransfer_3 PF13469.1 AEO71876.1 - 0.037 14.9 10.8 0.075 13.9 7.4 1.6 1 1 0 1 1 1 0 Sulfotransferase family Epimerase PF01370.16 AEO71877.1 - 2.7e-13 49.9 0.0 3.1e-12 46.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO71877.1 - 3.6e-06 26.0 0.1 0.0011 17.9 0.1 2.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 AEO71877.1 - 2.9e-05 24.0 0.1 6.1e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 AEO71877.1 - 9.5e-05 21.4 0.0 0.049 12.5 0.0 2.4 1 1 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.14 AEO71877.1 - 0.0013 17.4 0.0 0.012 14.2 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 AEO71877.1 - 0.0088 16.0 0.0 0.044 13.7 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 AEO71877.1 - 0.02 13.8 0.0 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.5 AEO71877.1 - 0.024 14.2 0.0 0.094 12.3 0.0 1.9 2 0 0 2 2 2 0 KR domain Ldh_1_N PF00056.18 AEO71877.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ABM PF03992.11 AEO71880.1 - 0.0079 16.2 0.1 2.8 8.0 0.0 2.4 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Metallophos PF00149.23 AEO71882.1 - 1.5e-20 73.4 0.6 2.6e-20 72.6 0.4 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 AEO71882.1 - 1.7e-17 63.2 0.2 3.6e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 AEO71882.1 - 5.3e-08 31.8 0.8 3e-07 29.3 0.5 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 AEO71882.1 - 0.002 17.9 0.0 0.0049 16.7 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PsiB PF06290.6 AEO71882.1 - 0.013 14.9 0.1 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) CfAFP PF05264.6 AEO71882.1 - 0.022 14.5 1.0 0.047 13.4 0.7 1.5 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) Pkinase PF00069.20 AEO71884.1 - 3.9e-07 29.4 0.0 5.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71884.1 - 0.00018 20.6 0.0 0.00026 20.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 AEO71884.1 - 0.047 13.0 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HET PF06985.6 AEO71885.1 - 1.6e-26 93.0 0.0 2.7e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Helicase_C_3 PF13625.1 AEO71887.1 - 1.5e-28 99.1 0.0 4.3e-28 97.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO71887.1 - 1.3e-13 51.1 0.0 2.3e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AEO71887.1 - 8e-10 38.4 0.0 1.8e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AEO71887.1 - 1.8e-07 30.2 0.0 2.9e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 AEO71887.1 - 9.1e-06 25.2 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Aminotran_3 PF00202.16 AEO71888.1 - 6.9e-36 123.7 0.0 1e-17 64.0 0.0 3.0 3 1 0 3 3 3 2 Aminotransferase class-III AAA_26 PF13500.1 AEO71888.1 - 2.5e-35 121.8 0.0 4.4e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain CFEM PF05730.6 AEO71889.1 - 1.5e-06 27.8 6.8 2.4e-06 27.2 4.7 1.2 1 0 0 1 1 1 1 CFEM domain rve PF00665.21 AEO71891.1 - 0.00019 21.5 0.0 0.00022 21.3 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Dimer_Tnp_hAT PF05699.9 AEO71892.1 - 1.7e-07 30.7 0.2 1.9e-07 30.6 0.2 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3012 PF11216.3 AEO71892.1 - 0.23 11.1 1.0 0.3 10.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) Abhydrolase_6 PF12697.2 AEO71893.1 - 3.1e-26 92.6 0.7 3.8e-26 92.3 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO71893.1 - 4.1e-12 46.0 0.1 5.4e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 AEO71894.1 - 1.6e-86 291.1 0.0 1.2e-85 288.2 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO71894.1 - 1.1e-07 31.6 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AEO71894.1 - 0.019 14.1 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Metallophos PF00149.23 AEO71895.1 - 6.4e-17 61.6 0.1 8.8e-16 57.8 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 AEO71895.1 - 2.8e-12 46.5 0.0 7.3e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 AEO71895.1 - 9.2e-10 37.6 0.2 5.9e-09 35.0 0.1 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 AEO71895.1 - 0.0012 18.6 0.0 0.0024 17.7 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain fn3 PF00041.16 AEO71895.1 - 0.0033 17.5 2.6 0.0071 16.4 1.8 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Cupin_2 PF07883.6 AEO71895.1 - 0.054 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Cupin domain zf-MYND PF01753.13 AEO71896.1 - 1.3e-08 34.5 9.7 2.6e-08 33.6 6.7 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 AEO71896.1 - 0.034 13.9 3.4 0.075 12.8 2.3 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 APH PF01636.18 AEO71897.1 - 8.7e-13 48.5 0.0 1.6e-12 47.6 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 AEO71897.1 - 4.3e-05 22.9 0.0 0.027 13.8 0.0 2.1 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 AEO71897.1 - 8.4e-05 22.2 0.0 0.00027 20.5 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 AEO71897.1 - 0.048 12.7 0.0 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 AEO71897.1 - 0.053 12.6 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF3328 PF11807.3 AEO71899.1 - 1.7e-40 139.0 0.1 1.7e-40 139.0 0.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) DUF3139 PF11337.3 AEO71899.1 - 0.091 13.0 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) DUF1579 PF07617.6 AEO71900.1 - 0.25 10.9 2.8 3.5 7.2 0.1 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1579) DHquinase_II PF01220.14 AEO71900.1 - 0.27 10.5 2.4 23 4.3 0.0 4.1 1 1 3 5 5 5 0 Dehydroquinase class II Ribosomal_S16 PF00886.14 AEO71900.1 - 1.9 8.2 5.2 3.1 7.6 0.1 3.2 1 1 2 3 3 3 0 Ribosomal protein S16 Cellulase PF00150.13 AEO71901.1 - 2.3e-19 69.6 4.7 3.3e-19 69.1 3.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 AEO71901.1 - 4.4e-05 22.5 0.0 0.00071 18.5 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 AEO71901.1 - 0.00019 21.8 0.0 0.00056 20.3 0.0 1.8 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 AEO71901.1 - 0.0039 16.3 0.1 0.015 14.4 0.0 1.9 3 0 0 3 3 3 1 Beta-galactosidase FAD_binding_4 PF01565.18 AEO71902.1 - 3.1e-17 62.3 1.1 5.9e-17 61.4 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO71902.1 - 1.3e-07 31.3 0.1 2.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 AEO71902.1 - 1.2e-06 27.5 24.4 1.2e-06 27.5 16.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily F-box PF00646.28 AEO71903.1 - 6.4e-08 32.0 0.3 1.5e-07 30.9 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 AEO71903.1 - 9.1e-06 25.3 0.4 9.1e-06 25.3 0.3 2.2 3 0 0 3 3 3 1 F-box-like MFS_1 PF07690.11 AEO71904.1 - 4.4e-31 107.8 36.5 4.4e-31 107.8 25.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TMEM18 PF14770.1 AEO71904.1 - 0.0019 17.6 0.3 0.0097 15.4 0.2 2.4 1 1 0 1 1 1 1 Transmembrane protein 18 PDGLE PF13190.1 AEO71904.1 - 0.041 13.5 1.2 0.26 10.9 0.0 2.7 2 0 0 2 2 2 0 PDGLE domain ADH_N PF08240.7 AEO71905.1 - 1.1e-22 79.9 5.9 2e-22 79.0 4.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO71905.1 - 2.2e-17 62.8 0.0 3.6e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 AEO71905.1 - 0.005 16.9 0.0 0.0089 16.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 AEO71905.1 - 0.031 13.4 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CFEM PF05730.6 AEO71906.1 - 1.1e-09 37.9 9.5 1.9e-09 37.2 6.6 1.4 1 0 0 1 1 1 1 CFEM domain TIL PF01826.12 AEO71906.1 - 0.043 13.9 2.6 0.043 13.9 1.8 1.7 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Aminotran_1_2 PF00155.16 AEO71907.1 - 1.3e-92 310.5 0.0 1.6e-92 310.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Ribosomal_L28 PF00830.14 AEO71909.1 - 4.2e-19 68.1 1.1 6.5e-19 67.5 0.7 1.3 1 0 0 1 1 1 1 Ribosomal L28 family DUF3439 PF11921.3 AEO71909.1 - 3.1 7.5 6.5 5.1 6.8 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Trp_syntA PF00290.15 AEO71910.1 - 1.1e-94 315.7 0.0 1.9e-94 315.0 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 AEO71910.1 - 1.7e-44 152.3 0.4 3.1e-44 151.4 0.3 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PcrB PF01884.12 AEO71910.1 - 0.0064 15.7 0.2 0.85 8.8 0.1 2.3 2 0 0 2 2 2 2 PcrB family Sensor PF13796.1 AEO71911.1 - 0.009 15.6 0.1 0.009 15.6 0.1 3.3 3 1 0 3 3 3 1 Putative sensor Phasin PF05597.6 AEO71911.1 - 0.048 13.4 0.0 2.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Peptidase_C97 PF05903.9 AEO71912.1 - 2.8e-06 27.1 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 AEO71912.1 - 5.3e-05 23.1 0.0 9.9e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Lecithin retinol acyltransferase APH PF01636.18 AEO71913.1 - 2.2e-18 66.8 0.0 2.7e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO71913.1 - 2.5e-05 23.9 0.0 4.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase GFA PF04828.9 AEO71914.1 - 1.9e-14 53.3 0.0 2.7e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DEAD PF00270.24 AEO71915.1 - 3.2e-43 147.1 0.0 6.5e-43 146.1 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 AEO71915.1 - 1.7e-21 75.5 0.1 4.2e-21 74.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 AEO71915.1 - 1.4e-20 72.9 0.0 4e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MSP PF01716.13 AEO71915.1 - 0.33 9.9 1.8 2.8 6.9 0.3 2.1 2 0 0 2 2 2 0 Manganese-stabilising protein / photosystem II polypeptide Daxx PF03344.10 AEO71915.1 - 3.1 6.1 14.1 4.6 5.6 9.8 1.2 1 0 0 1 1 1 0 Daxx Family C1_4 PF07975.7 AEO71916.1 - 0.52 10.3 6.1 1.6 8.8 0.0 2.3 1 1 1 2 2 2 0 TFIIH C1-like domain 6PF2K PF01591.13 AEO71917.1 - 9.9e-79 263.5 0.0 1.4e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 AEO71917.1 - 2e-32 112.5 0.2 4.3e-32 111.4 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 AEO71917.1 - 2e-07 30.9 0.0 3.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO71917.1 - 0.00057 20.7 0.2 0.009 16.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 AEO71917.1 - 0.00065 19.0 0.0 0.00095 18.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 AEO71917.1 - 0.063 12.3 0.0 0.31 10.1 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Asp PF00026.18 AEO71918.1 - 3.9e-43 147.9 0.0 5.6e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 AEO71918.1 - 1.7e-07 31.6 0.0 0.91 10.0 0.0 3.4 3 0 0 3 3 3 3 Aspartyl protease TAXi_C PF14541.1 AEO71918.1 - 4.2e-07 29.6 0.1 8.7e-06 25.3 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 AEO71918.1 - 6.9e-06 25.7 0.0 0.049 13.4 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease KH_1 PF00013.24 AEO71919.1 - 1e-44 149.9 8.3 2.4e-16 59.1 0.5 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 AEO71919.1 - 1e-32 111.2 16.3 1.9e-12 46.5 0.7 4.2 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 AEO71919.1 - 3e-13 49.1 1.1 0.0096 15.4 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 AEO71919.1 - 6.7e-09 35.2 1.5 0.092 12.4 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 AEO71919.1 - 4.9e-05 23.0 0.7 0.094 12.5 0.0 3.2 3 0 0 3 3 3 2 NusA-like KH domain DUF829 PF05705.9 AEO71920.1 - 5.3e-33 114.6 0.0 2.7e-32 112.3 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Glycos_transf_N PF04413.11 AEO71920.1 - 0.15 11.1 0.4 0.26 10.4 0.3 1.3 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Kelch_3 PF13415.1 AEO71920.1 - 1.9 8.7 7.7 30 4.9 0.3 3.9 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF1272 PF06906.6 AEO71921.1 - 0.01 15.6 3.6 0.09 12.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-Di19 PF05605.7 AEO71921.1 - 0.047 13.8 2.2 0.18 11.9 1.5 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C4_Topoisom PF01396.14 AEO71921.1 - 0.057 12.9 0.4 12 5.4 0.0 2.5 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger TF_Zn_Ribbon PF08271.7 AEO71921.1 - 0.13 11.6 4.1 0.2 11.0 0.2 2.5 2 1 1 3 3 3 0 TFIIB zinc-binding zf-RanBP PF00641.13 AEO71921.1 - 0.3 10.2 2.3 3.7 6.7 0.1 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zinc-ribbons_6 PF07191.7 AEO71921.1 - 0.48 10.2 4.6 3.4 7.5 0.3 2.2 1 1 1 2 2 2 0 zinc-ribbons Lar_restr_allev PF14354.1 AEO71921.1 - 3.3 8.0 5.7 7.7 6.9 3.9 1.6 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-RING_3 PF14369.1 AEO71921.1 - 5.5 7.0 6.2 0.69 9.9 0.8 2.1 2 0 0 2 2 2 0 zinc-finger Pkinase PF00069.20 AEO71923.1 - 4.4e-14 52.2 0.0 6e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 AEO71923.1 - 8.7e-07 28.9 1.3 4.5e-06 26.5 0.7 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 AEO71923.1 - 1e-06 28.0 0.0 1.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO71923.1 - 2.9e-05 23.2 0.0 5.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 AEO71923.1 - 0.0013 18.4 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 AEO71923.1 - 0.049 12.9 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 AEO71923.1 - 0.073 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 AEO71923.1 - 0.16 10.7 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MFS_1 PF07690.11 AEO71924.1 - 7.7e-38 130.1 29.6 9.6e-38 129.7 20.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TOMM6 PF15184.1 AEO71924.1 - 0.092 12.0 0.1 0.28 10.5 0.1 1.9 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog p450 PF00067.17 AEO71925.1 - 1.3e-67 228.3 0.0 1.7e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 AEO71926.1 - 2.9e-19 69.6 0.1 5.1e-19 68.8 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO71926.1 - 1.9e-08 34.1 0.0 3.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO71926.1 - 2.6e-05 24.1 0.0 4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AEO71926.1 - 0.004 16.6 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 AEO71926.1 - 0.031 14.3 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 AEO71926.1 - 0.031 14.2 0.5 0.059 13.3 0.3 1.7 1 1 0 1 1 1 0 NADH(P)-binding Saccharop_dh PF03435.13 AEO71926.1 - 0.036 13.0 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Rep_fac_C PF08542.6 AEO71927.1 - 1.5e-18 66.5 0.1 4.2e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 AEO71927.1 - 5.9e-16 58.8 0.2 1.3e-15 57.7 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 AEO71927.1 - 2.4e-14 53.2 0.0 5.6e-14 52.1 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 AEO71927.1 - 1.7e-08 33.6 0.0 2.3e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 AEO71927.1 - 5e-07 29.9 0.2 4.4e-06 26.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AEO71927.1 - 1.5e-06 28.3 0.0 3e-05 24.0 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 AEO71927.1 - 1.6e-05 24.5 0.0 4.1e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_delta PF06144.8 AEO71927.1 - 2.5e-05 23.8 0.0 4.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.1 AEO71927.1 - 4e-05 23.2 0.0 7.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 AEO71927.1 - 4.2e-05 22.4 0.0 0.065 11.9 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_11 PF13086.1 AEO71927.1 - 5.3e-05 22.9 0.1 0.00067 19.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 AEO71927.1 - 6.8e-05 22.0 0.0 0.00032 19.8 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 AEO71927.1 - 8.7e-05 22.4 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO71927.1 - 0.00026 20.7 0.1 0.00066 19.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AEO71927.1 - 0.00027 20.5 0.5 0.0035 16.9 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 AEO71927.1 - 0.0003 19.7 0.0 0.0005 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.11 AEO71927.1 - 0.0012 18.1 0.3 0.84 8.8 0.0 2.6 1 1 1 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 AEO71927.1 - 0.0027 17.3 0.1 0.0069 15.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 AEO71927.1 - 0.0033 17.4 0.1 0.0078 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 AEO71927.1 - 0.0044 16.5 0.0 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain TK PF00265.13 AEO71927.1 - 0.005 16.4 0.0 0.012 15.1 0.0 1.6 2 0 0 2 2 1 1 Thymidine kinase AAA_25 PF13481.1 AEO71927.1 - 0.0087 15.4 0.1 0.039 13.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain DUF2075 PF09848.4 AEO71927.1 - 0.01 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 AEO71927.1 - 0.013 15.7 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AEO71927.1 - 0.015 16.0 0.0 0.032 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 AEO71927.1 - 0.017 14.6 0.3 0.23 10.9 0.0 2.5 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_10 PF12846.2 AEO71927.1 - 0.02 14.3 0.2 2.6 7.3 0.0 2.4 1 1 1 2 2 2 0 AAA-like domain Mg_chelatase PF01078.16 AEO71927.1 - 0.023 13.8 0.1 0.14 11.2 0.1 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.10 AEO71927.1 - 0.025 14.3 0.0 0.11 12.2 0.0 1.9 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 AEO71927.1 - 0.037 14.2 0.0 0.073 13.2 0.0 1.7 1 1 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 AEO71927.1 - 0.053 12.3 0.0 1.7 7.3 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain RPAP3_C PF13877.1 AEO71927.1 - 0.069 13.1 0.3 1.8 8.5 0.1 2.8 2 1 0 2 2 1 0 Potential Monad-binding region of RPAP3 IstB_IS21 PF01695.12 AEO71927.1 - 0.071 12.5 0.0 0.65 9.3 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.22 AEO71927.1 - 0.09 13.0 0.0 0.18 12.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter UDPGT PF00201.13 AEO71928.1 - 3e-10 39.2 0.1 8.1e-10 37.8 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Asp PF00026.18 AEO71929.1 - 1.3e-50 172.5 0.2 1.8e-50 172.0 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO71929.1 - 2.1e-06 27.7 0.5 2.1e-06 27.7 0.4 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 AEO71929.1 - 0.00044 19.8 0.0 0.0044 16.5 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal adh_short PF00106.20 AEO71931.1 - 1.5e-18 67.2 0.3 2.4e-18 66.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO71931.1 - 6e-07 29.3 0.2 3e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 AEO71931.1 - 0.057 12.3 0.1 0.14 11.0 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Microtub_assoc PF07989.6 AEO71932.1 - 3.6e-05 23.5 6.2 0.00011 22.0 4.3 1.8 1 0 0 1 1 1 1 Microtubule associated CENP-F_leu_zip PF10473.4 AEO71932.1 - 0.011 15.6 10.9 0.75 9.6 8.2 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.7 AEO71932.1 - 0.055 13.8 9.9 0.18 12.2 3.6 3.1 2 0 0 2 2 2 0 SlyX APG6 PF04111.7 AEO71932.1 - 0.27 10.2 3.8 0.42 9.6 2.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 AATF-Che1 PF13339.1 AEO71932.1 - 0.42 10.7 7.3 0.47 10.6 0.9 2.9 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor IncA PF04156.9 AEO71932.1 - 0.75 9.3 8.3 1.8 8.0 5.7 1.7 1 0 0 1 1 1 0 IncA protein EIAV_Rev PF11129.3 AEO71932.1 - 1.5 8.7 5.2 0.59 10.1 0.5 2.7 3 0 0 3 3 3 0 Rev protein of equine infectious anaemia virus NAD_binding_10 PF13460.1 AEO71933.1 - 1.9e-08 34.5 0.1 2.5e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 AEO71933.1 - 0.019 13.6 0.0 0.03 13.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AEO71933.1 - 0.023 14.1 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO71933.1 - 0.03 13.2 0.0 0.28 10.0 0.0 2.1 1 1 1 2 2 2 0 Male sterility protein Asp PF00026.18 AEO71934.1 - 0.0024 17.1 0.0 0.0038 16.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Choline_kinase PF01633.15 AEO71935.1 - 0.031 13.8 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-3CxxC PF13695.1 AEO71936.1 - 2.1e-24 85.6 0.3 2.5e-24 85.3 0.2 1.1 1 0 0 1 1 1 1 Zinc-binding domain zf-C3HC PF07967.8 AEO71936.1 - 0.56 9.9 3.0 1 9.0 0.4 2.1 1 1 1 2 2 2 0 C3HC zinc finger-like GMC_oxred_N PF00732.14 AEO71939.1 - 6.1e-56 189.7 0.0 1.1e-55 188.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO71939.1 - 8.1e-31 107.2 1.3 1.9e-30 106.0 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 AEO71939.1 - 1.1e-08 34.3 2.4 2.9e-05 23.1 0.0 3.0 4 0 0 4 4 4 2 FAD binding domain DAO PF01266.19 AEO71939.1 - 5e-07 28.9 9.9 1.5e-06 27.3 4.2 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 AEO71939.1 - 3.5e-06 26.1 0.2 6.7e-06 25.2 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 AEO71939.1 - 2.3e-05 24.3 0.0 0.00028 20.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO71939.1 - 5.3e-05 23.1 0.2 0.00016 21.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AEO71939.1 - 0.0011 19.1 0.4 0.62 10.0 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO71939.1 - 0.0012 19.1 1.0 0.0079 16.5 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO71939.1 - 0.0017 17.4 0.3 0.0036 16.4 0.2 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 AEO71939.1 - 0.0023 16.4 1.0 0.014 13.9 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein TrkA_N PF02254.13 AEO71939.1 - 0.0052 16.7 0.1 0.022 14.7 0.0 2.1 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_3 PF01494.14 AEO71939.1 - 0.0073 15.4 0.1 0.016 14.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 AEO71939.1 - 0.012 14.2 0.3 0.019 13.6 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 AEO71939.1 - 0.031 14.0 0.3 0.15 11.8 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.11 AEO71939.1 - 0.079 12.4 0.4 1.9 7.9 0.1 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA K_oxygenase PF13434.1 AEO71939.1 - 0.13 11.1 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) MFS_1 PF07690.11 AEO71940.1 - 8.5e-36 123.3 54.0 1.3e-35 122.7 35.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO71940.1 - 4.3e-11 42.0 10.8 4.3e-11 42.0 7.5 3.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 AEO71940.1 - 2.2e-09 36.1 23.0 2.9e-09 35.6 15.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TRAP-gamma PF07074.7 AEO71940.1 - 1.7 8.1 5.5 2.2 7.8 1.0 2.5 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) MFS_1 PF07690.11 AEO71942.1 - 1.8e-39 135.4 57.1 3e-38 131.4 39.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO71942.1 - 8.8e-14 50.9 40.8 1.3e-13 50.3 10.1 3.1 1 1 1 3 3 3 2 Sugar (and other) transporter 7tm_7 PF08395.7 AEO71942.1 - 1.7 7.6 9.9 0.21 10.5 0.8 3.1 2 1 0 3 3 3 0 7tm Chemosensory receptor DUF3923 PF13061.1 AEO71943.1 - 6.3 6.7 12.1 5.5 6.9 2.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3923) Pyr_redox_3 PF13738.1 AEO71944.1 - 5.7e-18 65.7 0.1 1.8e-17 64.0 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO71944.1 - 1.8e-07 31.2 0.0 2.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AEO71944.1 - 3.1e-07 28.9 0.0 5.1e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 AEO71944.1 - 3.9e-07 29.3 0.1 1.9e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 AEO71944.1 - 0.0017 18.3 0.3 0.0071 16.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO71944.1 - 0.0082 15.0 0.1 1.5 7.6 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase PRKCSH PF07915.8 AEO71945.1 - 1.8e-19 70.3 0.1 1.8e-19 70.3 0.1 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein HCV_NS4b PF01001.14 AEO71946.1 - 0.26 10.6 3.0 0.14 11.5 0.5 1.7 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4b DUF1635 PF07795.6 AEO71947.1 - 0.0025 17.2 0.1 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) Pkinase PF00069.20 AEO71948.1 - 1.5e-33 116.0 0.0 3.7e-33 114.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71948.1 - 1.7e-13 50.2 0.0 2.3e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 AEO71948.1 - 0.0068 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 AEO71948.1 - 0.013 15.2 0.1 0.18 11.5 0.0 2.4 2 1 0 3 3 3 0 Phosphotransferase enzyme family Melibiase PF02065.13 AEO71949.1 - 2.8e-18 65.8 0.9 3.6e-16 58.8 0.0 2.4 1 1 1 3 3 3 2 Melibiase MFS_1 PF07690.11 AEO71950.1 - 8.9e-28 97.0 27.3 3.1e-15 55.7 7.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO71950.1 - 2.5e-05 23.0 8.8 2.5e-05 23.0 6.1 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 AEO71950.1 - 0.029 14.1 0.2 0.029 14.1 0.1 2.8 3 0 0 3 3 3 0 MFS_1 like family OATP PF03137.15 AEO71950.1 - 1.8 6.5 4.2 16 3.3 0.1 3.1 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF1674 PF07896.7 AEO71951.1 - 6.9e-16 58.1 1.5 1.4e-15 57.2 1.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) TFIIA PF03153.8 AEO71951.1 - 6.8 6.4 5.8 7.7 6.3 4.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rxt3 PF08642.5 AEO71952.1 - 8.1e-30 103.4 0.3 2.7e-29 101.7 0.0 2.0 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 AEO71952.1 - 1.8e-05 24.6 0.0 0.00071 19.5 0.0 2.4 2 0 0 2 2 2 1 LCCL domain Pro-kuma_activ PF09286.6 AEO71953.1 - 5.9e-33 113.9 0.0 8.9e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 AEO71953.1 - 1e-09 37.9 1.9 1.6e-09 37.3 1.3 1.2 1 0 0 1 1 1 1 Subtilase family DoxX PF07681.7 AEO71955.1 - 0.62 10.5 3.4 2.1 8.8 0.3 2.2 2 0 0 2 2 2 0 DoxX Bromodomain PF00439.20 AEO71956.1 - 2e-37 126.9 0.1 2e-23 82.0 0.1 3.0 3 0 0 3 3 3 2 Bromodomain ApoO PF09769.4 AEO71956.1 - 6 6.5 7.3 6.8 6.3 0.4 2.6 2 0 0 2 2 2 0 Apolipoprotein O Syntaxin PF00804.20 AEO71956.1 - 8 6.6 14.6 2.3 8.4 2.7 2.6 2 0 0 2 2 2 0 Syntaxin Utp12 PF04003.7 AEO71957.1 - 1e-22 80.0 0.0 1.5e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family DUF2213 PF09979.4 AEO71957.1 - 0.014 15.0 0.2 0.031 13.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2213) SSP160 PF06933.6 AEO71959.1 - 0.075 11.0 0.0 0.091 10.7 0.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FAP PF07174.6 AEO71959.1 - 0.17 11.1 8.1 0.19 11.0 5.6 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) GPI-anchored PF10342.4 AEO71960.1 - 9.9e-17 61.2 1.0 1.4e-16 60.7 0.2 1.5 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_3_4 PF13754.1 AEO71960.1 - 0.066 13.5 1.4 1.3 9.4 0.0 3.0 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Pyrophosphatase PF00719.14 AEO71961.1 - 4e-49 166.0 0.0 6e-49 165.4 0.0 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase Pkinase PF00069.20 AEO71962.1 - 1.8e-29 102.6 0.0 3.4e-29 101.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO71962.1 - 1.3e-15 57.1 0.0 3.2e-15 55.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO71962.1 - 0.00017 21.3 0.3 0.24 11.1 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Competence PF03772.11 AEO71962.1 - 0.0054 15.8 0.0 0.0085 15.1 0.0 1.2 1 0 0 1 1 1 1 Competence protein Kdo PF06293.9 AEO71962.1 - 0.0057 15.7 0.0 0.0098 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family VWA_3 PF13768.1 AEO71963.1 - 3.1e-12 46.4 0.0 1.1e-06 28.4 0.0 2.6 1 1 1 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 AEO71963.1 - 3.6e-05 23.9 0.0 0.00036 20.6 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.5 AEO71963.1 - 5.3e-05 22.8 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 AEO71963.1 - 0.098 12.3 0.0 0.53 9.9 0.0 2.0 1 1 1 2 2 2 0 von Willebrand factor type A domain Peptidase_M13_N PF05649.8 AEO71964.1 - 1e-60 205.8 0.0 1.3e-60 205.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 AEO71964.1 - 3.4e-43 147.2 0.0 8.5e-43 145.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M13 CLN3 PF02487.12 AEO71965.1 - 1.5e-94 317.1 25.2 3.3e-52 177.6 0.8 3.3 2 1 0 2 2 2 2 CLN3 protein Cnd2 PF05786.9 AEO71968.1 - 2.4 6.5 5.2 3.9 5.8 3.6 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF1741 PF08427.5 AEO71969.1 - 1.1e-83 280.3 0.0 1.8e-83 279.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Fe-S_biosyn PF01521.15 AEO71970.1 - 3.3e-19 68.8 0.0 4.2e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF2890 PF11081.3 AEO71970.1 - 0.023 14.7 0.5 0.037 14.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) PAT1 PF09770.4 AEO71970.1 - 6.9 4.7 18.9 8.3 4.5 13.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MgsA_C PF12002.3 AEO71971.1 - 5.4e-60 201.9 0.1 1.1e-59 200.8 0.0 1.5 2 0 0 2 2 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 AEO71971.1 - 1.6e-12 47.7 0.0 3.1e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AEO71971.1 - 5e-11 42.1 0.0 4.6e-09 35.6 0.0 2.1 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 AEO71971.1 - 1e-05 25.0 0.0 0.0008 18.9 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 AEO71971.1 - 2.1e-05 24.6 4.7 0.0058 16.6 0.0 3.6 2 2 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 AEO71971.1 - 9.4e-05 22.0 0.3 0.00056 19.6 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 AEO71971.1 - 0.00016 21.8 0.6 0.0022 18.1 0.4 2.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO71971.1 - 0.0003 20.5 0.2 0.011 15.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AEO71971.1 - 0.00038 20.3 0.0 0.00069 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 AEO71971.1 - 0.00047 18.9 0.0 0.0035 16.1 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus Mg_chelatase PF01078.16 AEO71971.1 - 0.00053 19.2 0.0 0.21 10.7 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 AEO71971.1 - 0.0029 16.5 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 AEO71971.1 - 0.0039 17.9 0.0 0.0078 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.1 AEO71971.1 - 0.019 14.6 0.0 1.5 8.4 0.0 2.2 1 1 1 2 2 2 0 DNA polymerase III, delta subunit AAA_3 PF07726.6 AEO71971.1 - 0.023 14.2 0.0 0.086 12.4 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 AEO71971.1 - 0.024 14.4 0.2 4.9 6.9 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Rad17 PF03215.10 AEO71971.1 - 0.037 12.7 0.0 0.97 8.0 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 AEO71971.1 - 0.039 13.3 1.2 7.6 5.8 0.1 2.9 2 1 1 3 3 3 0 AAA-like domain SKI PF01202.17 AEO71971.1 - 0.063 13.1 0.1 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_28 PF13521.1 AEO71971.1 - 0.064 13.2 0.1 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AEO71971.1 - 0.12 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 AEO71971.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein zf-C2HC_2 PF13913.1 AEO71971.1 - 0.14 11.8 0.7 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TrwB_AAD_bind PF10412.4 AEO71971.1 - 0.22 10.1 0.0 0.33 9.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.17 AEO71971.1 - 0.27 10.0 0.0 0.44 9.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF427 PF04248.7 AEO71972.1 - 9.7e-30 102.1 1.1 1.1e-29 101.9 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) PEP_mutase PF13714.1 AEO71973.1 - 1.2e-05 24.6 0.0 0.00016 20.9 0.0 2.0 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF1992 PF09350.5 AEO71976.1 - 6.4e-26 89.9 0.5 1.5e-25 88.7 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Totivirus_coat PF05518.6 AEO71976.1 - 0.66 7.7 7.5 1 7.1 5.2 1.2 1 0 0 1 1 1 0 Totivirus coat protein